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Search of human proteins with 169217968
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|169217968 PREDICTED: similar to solute carrier family 16,
member 5 [Homo sapiens]
(453 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|169217968 PREDICTED: similar to solute carrier family 16, mem... 919 0.0
gi|4759116 solute carrier family 16, member 5 [Homo sapiens] 890 0.0
gi|109288010 solute carrier family 16, member 3 [Homo sapiens] 264 1e-70
gi|109288012 solute carrier family 16, member 3 [Homo sapiens] 264 1e-70
gi|4759112 solute carrier family 16, member 3 [Homo sapiens] 264 1e-70
gi|114796626 solute carrier family 16, member 8 [Homo sapiens] 256 4e-68
gi|24431958 solute carrier family 16, member 7 [Homo sapiens] 240 2e-63
gi|115583685 solute carrier family 16, member 1 [Homo sapiens] 191 1e-48
gi|157041233 solute carrier family 16 (monocarboxylic acid trans... 177 2e-44
gi|23503293 solute carrier family 16, member 11 [Homo sapiens] 158 8e-39
gi|42475555 monocarboxylate transporter 13 [Homo sapiens] 151 1e-36
gi|41327156 solute carrier family 16 (monocarboxylic acid transp... 130 3e-30
gi|5730045 solute carrier family 16, member 2 [Homo sapiens] 124 2e-28
gi|18699730 solute carrier family 16, member 10 [Homo sapiens] 123 3e-28
gi|40789261 solute carrier family 16, member 6 [Homo sapiens] 108 8e-24
gi|34916028 solute carrier family 16 (monocarboxylic acid transp... 96 7e-20
gi|4759114 solute carrier family 16, member 4 [Homo sapiens] 78 2e-14
gi|215272392 solute carrier family 18 (vesicular monoamine), mem... 37 0.028
gi|215272390 solute carrier family 18 (vesicular monoamine), mem... 37 0.028
gi|208879454 solute carrier family 18 (vesicular monoamine), mem... 37 0.028
gi|4506987 solute carrier family 18 (vesicular monoamine), membe... 37 0.028
gi|148743791 solute carrier family 17 (sodium phosphate), member... 35 0.11
gi|148728191 solute carrier family 17 (sodium phosphate), member... 35 0.11
gi|12232393 major facilitator superfamily domain containing 1 [H... 35 0.11
gi|42476325 solute carrier family 18 (vesicular monoamine), memb... 34 0.31
gi|122937193 DNB5 [Homo sapiens] 33 0.53
gi|38348211 golgi transport 1 homolog A [Homo sapiens] 33 0.69
gi|4885441 solute carrier family 17 (sodium phosphate), member 4... 32 0.91
gi|148664184 solute carrier family 22, member 10 [Homo sapiens] 32 1.5
gi|52353332 olfactory receptor, family 52, subfamily D, member 1... 32 1.5
>gi|169217968 PREDICTED: similar to solute carrier family 16, member
5 [Homo sapiens]
Length = 453
Score = 919 bits (2376), Expect = 0.0
Identities = 453/453 (100%), Positives = 453/453 (100%)
Query: 1 MRTHFPVPLVALSERPLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGF 60
MRTHFPVPLVALSERPLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGF
Sbjct: 1 MRTHFPVPLVALSERPLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGF 60
Query: 61 ITGLGMCFSFQSSITVLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTF 120
ITGLGMCFSFQSSITVLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTF
Sbjct: 61 ITGLGMCFSFQSSITVLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTF 120
Query: 121 LVFGGIFLHCCICGAIIRPVATSVAPETKECPPPPPETPALGCLAACGRTIQRHLAFDIL 180
LVFGGIFLHCCICGAIIRPVATSVAPETKECPPPPPETPALGCLAACGRTIQRHLAFDIL
Sbjct: 121 LVFGGIFLHCCICGAIIRPVATSVAPETKECPPPPPETPALGCLAACGRTIQRHLAFDIL 180
Query: 181 RHNTGYCVYILGVMWSVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFLRPLAG 240
RHNTGYCVYILGVMWSVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFLRPLAG
Sbjct: 181 RHNTGYCVYILGVMWSVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFLRPLAG 240
Query: 241 LMAGRPAFASHRKYLFSLALLLNGLTNLVCAASGDFWVLVGYCLAYSVSMSGIGALIFQV 300
LMAGRPAFASHRKYLFSLALLLNGLTNLVCAASGDFWVLVGYCLAYSVSMSGIGALIFQV
Sbjct: 241 LMAGRPAFASHRKYLFSLALLLNGLTNLVCAASGDFWVLVGYCLAYSVSMSGIGALIFQV 300
Query: 301 LMDIVPMDQFPRALGLFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMSSFFLISAALFM 360
LMDIVPMDQFPRALGLFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMSSFFLISAALFM
Sbjct: 301 LMDIVPMDQFPRALGLFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMSSFFLISAALFM 360
Query: 361 GGSFYALQKKEQGKQAVAADALERDLFLEAKDGPGKQRSPEIMCQSSRQPRPAGVNKHLW 420
GGSFYALQKKEQGKQAVAADALERDLFLEAKDGPGKQRSPEIMCQSSRQPRPAGVNKHLW
Sbjct: 361 GGSFYALQKKEQGKQAVAADALERDLFLEAKDGPGKQRSPEIMCQSSRQPRPAGVNKHLW 420
Query: 421 GCPASSRTSHEWLLWPKAVLQAKQTALGWNSPT 453
GCPASSRTSHEWLLWPKAVLQAKQTALGWNSPT
Sbjct: 421 GCPASSRTSHEWLLWPKAVLQAKQTALGWNSPT 453
>gi|4759116 solute carrier family 16, member 5 [Homo sapiens]
Length = 505
Score = 890 bits (2300), Expect = 0.0
Identities = 442/451 (98%), Positives = 443/451 (98%), Gaps = 2/451 (0%)
Query: 5 FPVPLVALSER--PLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFIT 62
FP L A+ PLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFIT
Sbjct: 55 FPSILTAVLHMAGPLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFIT 114
Query: 63 GLGMCFSFQSSITVLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLV 122
GLGMCFSFQSSITVLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLV
Sbjct: 115 GLGMCFSFQSSITVLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLV 174
Query: 123 FGGIFLHCCICGAIIRPVATSVAPETKECPPPPPETPALGCLAACGRTIQRHLAFDILRH 182
FGGIFLHCCICGAIIRPVATSVAPETKECPPPPPETPALGCLAACGRTIQRHLAFDILRH
Sbjct: 175 FGGIFLHCCICGAIIRPVATSVAPETKECPPPPPETPALGCLAACGRTIQRHLAFDILRH 234
Query: 183 NTGYCVYILGVMWSVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFLRPLAGLM 242
NTGYCVYILGVMWSVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFLRPLAGLM
Sbjct: 235 NTGYCVYILGVMWSVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFLRPLAGLM 294
Query: 243 AGRPAFASHRKYLFSLALLLNGLTNLVCAASGDFWVLVGYCLAYSVSMSGIGALIFQVLM 302
AGRPAFASHRKYLFSLALLLNGLTNLVCAASGDFWVLVGYCLAYSVSMSGIGALIFQVLM
Sbjct: 295 AGRPAFASHRKYLFSLALLLNGLTNLVCAASGDFWVLVGYCLAYSVSMSGIGALIFQVLM 354
Query: 303 DIVPMDQFPRALGLFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMSSFFLISAALFMGG 362
DIVPMDQFPRALGLFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMSSFFLISAALFMGG
Sbjct: 355 DIVPMDQFPRALGLFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMSSFFLISAALFMGG 414
Query: 363 SFYALQKKEQGKQAVAADALERDLFLEAKDGPGKQRSPEIMCQSSRQPRPAGVNKHLWGC 422
SFYALQKKEQGKQAVAADALERDLFLEAKDGPGKQRSPEIMCQSSRQPRPAGVNKHLWGC
Sbjct: 415 SFYALQKKEQGKQAVAADALERDLFLEAKDGPGKQRSPEIMCQSSRQPRPAGVNKHLWGC 474
Query: 423 PASSRTSHEWLLWPKAVLQAKQTALGWNSPT 453
PASSRTSHEWLLWPKAVLQAKQTALGWNSPT
Sbjct: 475 PASSRTSHEWLLWPKAVLQAKQTALGWNSPT 505
>gi|109288010 solute carrier family 16, member 3 [Homo sapiens]
Length = 465
Score = 264 bits (674), Expect = 1e-70
Identities = 144/372 (38%), Positives = 221/372 (59%), Gaps = 19/372 (5%)
Query: 16 PLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCFSFQSSIT 75
PLCS+ V RFGCR +++GG+ ASLGMVA+SF ++ Q+Y T G ITGLG+ +FQ S+
Sbjct: 76 PLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLALNFQPSLI 135
Query: 76 VLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFLHCCICGA 135
+L YF +RR +AN LA+ G + + L + L + GWRG FL+ GG+ L+CC+C A
Sbjct: 136 MLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLLLNCCVCAA 195
Query: 136 IIRPVATSVAPETKECPPPPPETPALGCLAACGRTIQRHLAFDILRHNTGYCVYILGVMW 195
++RP+ + P + PP P +R L + R + G+ +Y +
Sbjct: 196 LMRPLVVTAQPGS---GPPRPS--------------RRLLDLSVFR-DRGFVLYAVAASV 237
Query: 196 SVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFLRPLAGLMAGRPAFASHRKYL 255
VLG +P VF+V YA V + +AA L++I+GF +IF RP AG +AG + YL
Sbjct: 238 MVLGLFVPPVFVVSYAKDLGVPDTKAAFLLTILGFIDIFARPAAGFVAGLGKVRPYSVYL 297
Query: 256 FSLALLLNGLTNLVCAASGDFWVLVGYCLAYSVSMSGIGALIFQVLMDIVPMDQFPRALG 315
FS ++ NGL +L + +GD+ LV +C+ + +S +GAL F+VLM IV +F A+G
Sbjct: 298 FSFSMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTHKFSSAIG 357
Query: 316 LFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMS-SFFLISAALFMGGSFYALQKKEQGK 374
L +++ +A L+ PP G LLDAT+ + YVF ++ + L S+ + + G+F+ ++KK +
Sbjct: 358 LVLLMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTSSLILLLGNFFCIRKKPKEP 417
Query: 375 QAVAADALERDL 386
Q A A E L
Sbjct: 418 QPEVAAAEEEKL 429
>gi|109288012 solute carrier family 16, member 3 [Homo sapiens]
Length = 465
Score = 264 bits (674), Expect = 1e-70
Identities = 144/372 (38%), Positives = 221/372 (59%), Gaps = 19/372 (5%)
Query: 16 PLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCFSFQSSIT 75
PLCS+ V RFGCR +++GG+ ASLGMVA+SF ++ Q+Y T G ITGLG+ +FQ S+
Sbjct: 76 PLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLALNFQPSLI 135
Query: 76 VLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFLHCCICGA 135
+L YF +RR +AN LA+ G + + L + L + GWRG FL+ GG+ L+CC+C A
Sbjct: 136 MLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLLLNCCVCAA 195
Query: 136 IIRPVATSVAPETKECPPPPPETPALGCLAACGRTIQRHLAFDILRHNTGYCVYILGVMW 195
++RP+ + P + PP P +R L + R + G+ +Y +
Sbjct: 196 LMRPLVVTAQPGS---GPPRPS--------------RRLLDLSVFR-DRGFVLYAVAASV 237
Query: 196 SVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFLRPLAGLMAGRPAFASHRKYL 255
VLG +P VF+V YA V + +AA L++I+GF +IF RP AG +AG + YL
Sbjct: 238 MVLGLFVPPVFVVSYAKDLGVPDTKAAFLLTILGFIDIFARPAAGFVAGLGKVRPYSVYL 297
Query: 256 FSLALLLNGLTNLVCAASGDFWVLVGYCLAYSVSMSGIGALIFQVLMDIVPMDQFPRALG 315
FS ++ NGL +L + +GD+ LV +C+ + +S +GAL F+VLM IV +F A+G
Sbjct: 298 FSFSMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTHKFSSAIG 357
Query: 316 LFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMS-SFFLISAALFMGGSFYALQKKEQGK 374
L +++ +A L+ PP G LLDAT+ + YVF ++ + L S+ + + G+F+ ++KK +
Sbjct: 358 LVLLMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTSSLILLLGNFFCIRKKPKEP 417
Query: 375 QAVAADALERDL 386
Q A A E L
Sbjct: 418 QPEVAAAEEEKL 429
>gi|4759112 solute carrier family 16, member 3 [Homo sapiens]
Length = 465
Score = 264 bits (674), Expect = 1e-70
Identities = 144/372 (38%), Positives = 221/372 (59%), Gaps = 19/372 (5%)
Query: 16 PLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCFSFQSSIT 75
PLCS+ V RFGCR +++GG+ ASLGMVA+SF ++ Q+Y T G ITGLG+ +FQ S+
Sbjct: 76 PLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLALNFQPSLI 135
Query: 76 VLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFLHCCICGA 135
+L YF +RR +AN LA+ G + + L + L + GWRG FL+ GG+ L+CC+C A
Sbjct: 136 MLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLLLNCCVCAA 195
Query: 136 IIRPVATSVAPETKECPPPPPETPALGCLAACGRTIQRHLAFDILRHNTGYCVYILGVMW 195
++RP+ + P + PP P +R L + R + G+ +Y +
Sbjct: 196 LMRPLVVTAQPGS---GPPRPS--------------RRLLDLSVFR-DRGFVLYAVAASV 237
Query: 196 SVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFLRPLAGLMAGRPAFASHRKYL 255
VLG +P VF+V YA V + +AA L++I+GF +IF RP AG +AG + YL
Sbjct: 238 MVLGLFVPPVFVVSYAKDLGVPDTKAAFLLTILGFIDIFARPAAGFVAGLGKVRPYSVYL 297
Query: 256 FSLALLLNGLTNLVCAASGDFWVLVGYCLAYSVSMSGIGALIFQVLMDIVPMDQFPRALG 315
FS ++ NGL +L + +GD+ LV +C+ + +S +GAL F+VLM IV +F A+G
Sbjct: 298 FSFSMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTHKFSSAIG 357
Query: 316 LFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMS-SFFLISAALFMGGSFYALQKKEQGK 374
L +++ +A L+ PP G LLDAT+ + YVF ++ + L S+ + + G+F+ ++KK +
Sbjct: 358 LVLLMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTSSLILLLGNFFCIRKKPKEP 417
Query: 375 QAVAADALERDL 386
Q A A E L
Sbjct: 418 QPEVAAAEEEKL 429
>gi|114796626 solute carrier family 16, member 8 [Homo sapiens]
Length = 504
Score = 256 bits (653), Expect = 4e-68
Identities = 146/356 (41%), Positives = 201/356 (56%), Gaps = 12/356 (3%)
Query: 16 PLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCFSFQSSIT 75
P+ SILV RFGCR ++ GG+LAS GM+ +SF+ L +LY TAG +TGLG+ +FQ S+
Sbjct: 73 PVSSILVTRFGCRPVMLAGGLLASAGMILASFATRLLELYLTAGVLTGLGLALNFQPSLI 132
Query: 76 VLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFLHCCICGA 135
+LG YF RRR LAN LA+ G + ++ L + LLE GWRG FL+ GG+ LHCC CGA
Sbjct: 133 MLGLYFERRRPLANGLAAAGSPVFLSALSPLGQQLLERFGWRGGFLLLGGLLLHCCACGA 192
Query: 136 IIRPVATSVAPETKECPPPPPETPALGCLAACGRTIQRHLAFDILR-----------HNT 184
++RP P + A G A G +Q A +R +
Sbjct: 193 VMRP-PPGPGPRPRRDSAGDRAGDAPGEAEADGAGLQLREASPRVRPRRRLLDLAVCTDR 251
Query: 185 GYCVYILGVMWSVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFLRPLAGLMAG 244
+ VY + LG +P + LV YA V + AA L+SI+GF +I RP G +AG
Sbjct: 252 AFAVYAVTKFLMALGLFVPAILLVNYAKDAGVPDTDAAFLLSIVGFVDIVARPACGALAG 311
Query: 245 RPAFASHRKYLFSLALLLNGLTNLVCAASGDFWVLVGYCLAYSVSMSGIGALIFQVLMDI 304
H YLFSLALL NGLT+L A + + LV +C+A+ +S +GAL F+VLM
Sbjct: 312 LARLRPHVPYLFSLALLANGLTDLSSARARSYGALVAFCVAFGLSYGMVGALQFEVLMAA 371
Query: 305 VPMDQFPRALGLFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMSSFFLISAALFM 360
V +FP ALGL +++ A LI PP AG L+D N+ +FY++ + A +FM
Sbjct: 372 VGAPRFPSALGLVLLVEAAAVLIGPPSAGRLVDVLKNYEIIFYLAGSEVALAGVFM 427
>gi|24431958 solute carrier family 16, member 7 [Homo sapiens]
Length = 478
Score = 240 bits (612), Expect = 2e-63
Identities = 130/384 (33%), Positives = 220/384 (57%), Gaps = 10/384 (2%)
Query: 16 PLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCFSFQSSIT 75
P+ S+LV ++G R V+ GG+L LGMV +SFS ++ QLY T GFITGLG+ F+ Q ++T
Sbjct: 74 PVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFITGLGLAFNLQPALT 133
Query: 76 VLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFLHCCICGA 135
++G YF R+R +AN LA G + ++ ++YL GW+G+FL+ G + L+ C+ G+
Sbjct: 134 IIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLILGSLLLNACVAGS 193
Query: 136 IIRPVA---TSVAPETKECPPPPPETPA-LGCLAACGRTIQRHLAFDILRHNTGYCVYIL 191
++RP+ T+ + K +P + + + ++L F + +H G+ +Y+
Sbjct: 194 LMRPLGPNQTTSKSKNKTGKTEDDSSPKKIKTKKSTWEKVNKYLDFSLFKHR-GFLIYLS 252
Query: 192 GVMWSVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFLRPLAGLMAGRPAFASH 251
G + LGF P +FL PYA +DE AA L+S++ F ++F RP GL+A
Sbjct: 253 GNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMAFVDMFARPSVGLIANSKYIRPR 312
Query: 252 RKYLFSLALLLNGLTNLVCAASGDFWVLVGYCLAYSVSMSGIGALIFQVLMDIVPMDQFP 311
+Y FS A++ NG+ +L+C + D+ LV Y + + + + +++F+ LMD+V +F
Sbjct: 313 IQYFFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFGSVSSVLFETLMDLVGAPRFS 372
Query: 312 RALGLFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMSSFFLISAA---LFMGGSF-YAL 367
A+GL T+++ L+ PPLAG L+D T + Y+ YMS ++ AA L +G + Y L
Sbjct: 373 SAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYM-YMSCGAIVVAASVWLLIGNAINYRL 431
Query: 368 QKKEQGKQAVAADALERDLFLEAK 391
KE+ ++ E + ++K
Sbjct: 432 LAKERKEENARQKTRESEPLSKSK 455
>gi|115583685 solute carrier family 16, member 1 [Homo sapiens]
Length = 500
Score = 191 bits (485), Expect = 1e-48
Identities = 117/407 (28%), Positives = 205/407 (50%), Gaps = 30/407 (7%)
Query: 16 PLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCFSFQSSIT 75
P+ SILV ++G R+ +++GG L+ G++A+SF + + QLY G I GLG+ F+ ++T
Sbjct: 74 PISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIGGLGLAFNLNPALT 133
Query: 76 VLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFLHCCICGA 135
++G YF +RR LAN LA G + + L++ GWRG+FL+ GG+ L+CC+ GA
Sbjct: 134 MIGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLILGGLLLNCCVAGA 193
Query: 136 IIRPVATSVAPETKECPPPPPE---------------TPALGC-----LAACGRTIQRHL 175
++RP+ K+ E T +G + +TI + L
Sbjct: 194 LMRPIGPKPTKAGKDKSKASLEKAGKSGVKKDLHDANTDLIGRHPKQEKRSVFQTINQFL 253
Query: 176 AFDILRHNTGYCVYILGVMWSVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFL 235
+ H G+ +Y+ G + G P VFL Y +++A L+SI+ F ++
Sbjct: 254 DLTLFTHR-GFLLYLSGNVIMFFGLFAPLVFLSSYGKSQHYSSEKSAFLLSILAFVDMVA 312
Query: 236 RPLAGLMAGRPAFASHRKYLFSLALLLNGLTNLVCAASGDFWVLVGYCL---AYSVSMSG 292
RP GL+A +Y F+ +++ NG+ +++ S + VG+C+ + +
Sbjct: 313 RPSMGLVANTKPIRPRIQYFFAASVVANGVCHMLAPLSTTY---VGFCVYAGFFGFAFGW 369
Query: 293 IGALIFQVLMDIVPMDQFPRALGLFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMSSFF 352
+ +++F+ LMD+V +F A+GL T+++ L+ PPL G L D ++ Y ++
Sbjct: 370 LSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVV 429
Query: 353 LISAA--LFMG-GSFYALQKKEQGKQAVAADALERDLFLEAKDGPGK 396
LI + LF+G G Y L KEQ ++ E + ++ P +
Sbjct: 430 LIISGIYLFIGMGINYRLLAKEQKANEQKKESKEEETSIDVAGKPNE 476
>gi|157041233 solute carrier family 16 (monocarboxylic acid
transporters), member 12 [Homo sapiens]
Length = 486
Score = 177 bits (449), Expect = 2e-44
Identities = 116/394 (29%), Positives = 193/394 (48%), Gaps = 22/394 (5%)
Query: 4 HFPVPLVALSERPLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITG 63
H V V + PL S++ C+V +MLGG+LAS G++ SSF+ +L LY T G +TG
Sbjct: 61 HSIVDCVTMLCAPLGSVVSNHLSCQVGIMLGGLLASTGLILSSFATSLKHLYLTLGVLTG 120
Query: 64 LGMCFSFQSSITVLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVF 123
LG + +I ++G YF RR+ LA +A G +G + + + L+E WRG L+
Sbjct: 121 LGFALCYSPAIAMVGKYFSRRKALAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLIL 180
Query: 124 GGIFLHCCICGAIIRPVATS---VAPE-----------TKECPPPPPETP--ALGCLAAC 167
GG L+ C+CGA++RP+ PE K P T A CL C
Sbjct: 181 GGFVLNLCVCGALMRPITLKEDHTTPEQNHVCRTQKEDIKRVSPYSSLTKEWAQTCLCCC 240
Query: 168 GRTIQRHLAFDILRHNTGYCVYILGVMWSVLGFPLPQVFLVPYAMWHSVDEQQAALLISI 227
+Q+ +F ++ + + V + V++ G V+LVPYA+ V QQAA L+SI
Sbjct: 241 ---LQQEYSFLLM---SDFVVLAVSVLFMAYGCSPLFVYLVPYALSVGVSHQQAAFLMSI 294
Query: 228 IGFSNIFLRPLAGLMAGRPAFASHRKYLFSLALLLNGLTNLVCAASGDFWVLVGYCLAYS 287
+G +I G + R +++ + A+ ++GL L +LV + +
Sbjct: 295 LGVIDIIGNITFGWLTDRRCLKNYQYVCYLFAVGMDGLCYLCLPMLQSLPLLVPFSCTFG 354
Query: 288 VSMSGIGALIFQVLMDIVPMDQFPRALGLFTVLDGLAFLISPPLAGLLLDATNNFSYVFY 347
LI V +IV ALG+ L + +L+SPP+AG L+D T +++ F
Sbjct: 355 YFDGAYVTLIPVVTTEIVGTTSLSSALGVVYFLHAVPYLVSPPIAGRLVDTTGSYTAAFL 414
Query: 348 MSSFFLISAALFMGGSFYALQKKEQGKQAVAADA 381
+ F +I +++ +G + + ++ Q +A ++
Sbjct: 415 LCGFSMIFSSVLLGFARLIKRMRKTQLQFIAKES 448
>gi|23503293 solute carrier family 16, member 11 [Homo sapiens]
Length = 471
Score = 158 bits (400), Expect = 8e-39
Identities = 119/354 (33%), Positives = 170/354 (48%), Gaps = 30/354 (8%)
Query: 16 PLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCFSFQSSIT 75
P+ S L R+G R VM+GGVLASLG V S+F+ +L LY G + G G F ++
Sbjct: 93 PVGSALSTRWGARPVVMVGGVLASLGFVFSAFASDLLHLYLGLGLLAGFGWALVFAPALG 152
Query: 76 VLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFLHCCICGA 135
L YF RRRVLA LA G L + LL+ GWRG L+ G I LH CGA
Sbjct: 153 TLSRYFSRRRVLAVGLALTGNGASSLLLAPALQLLLDTFGWRGALLLLGAITLHLTPCGA 212
Query: 136 IIRPVATSVAPETKECPPPPPETPALGCLAACGRTIQRHLAFDILRHNTGYCVYILGVMW 195
++ P+ V P PP PP +P LAA G ++ AF I + LG
Sbjct: 213 LLLPL---VLPGD---PPAPPRSP----LAALGLSLFTRRAFSI---------FALGTAL 253
Query: 196 SVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFLRPLAGLMAGR-----PAFAS 250
G+ +P V L P+A+ + AAL++++ + R + G +A + P +
Sbjct: 254 VGGGYFVPYVHLAPHALDRGLGGYGAALVVAVAAMGDAGARLVCGWLADQGWVPLPRLLA 313
Query: 251 HRKYLFSLALLLNGLTNLVCAASGDFWVLVGYCLAYSVSMSGIGALIFQVLMDIVPMDQF 310
L L L + GL +V L+ +AY +S L+F VL +V +
Sbjct: 314 VFGALTGLGLWVVGLVPVVGGEESWGGPLLAAAVAYGLSAGSYAPLVFGVLPGLVGVGGV 373
Query: 311 PRALGLFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMSSFFLISAALFMGGSF 364
+A GL +L L L+ PPL+G L D T +F ++ FL+S +L + GSF
Sbjct: 374 VQATGLVMMLMSLGGLLGPPLSGFLRDETGDF------TASFLLSGSLILSGSF 421
>gi|42475555 monocarboxylate transporter 13 [Homo sapiens]
Length = 426
Score = 151 bits (382), Expect = 1e-36
Identities = 106/370 (28%), Positives = 174/370 (47%), Gaps = 26/370 (7%)
Query: 16 PLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCFSFQSSIT 75
P+ S L +FG R VM GG+LA+LGM+ +SF+ +L+ LY + G ++G G +F ++
Sbjct: 68 PVGSALSTKFGPRPVVMTGGILAALGMLLASFATSLTHLYLSIGLLSGSGWALTFAPTLA 127
Query: 76 VLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFLHCCICGA 135
L YF RRR LA LA GV L + ++LL + WRG+ L+ + LH CGA
Sbjct: 128 CLSCYFSRRRSLATGLALTGVGLSSFTFAPFFQWLLSHYAWRGSLLLVSALSLHLVACGA 187
Query: 136 IIRPVATSVAPETKECPPPPPETPALGCLAACGRTIQRHLAFDILRHNTGYCVYILGVMW 195
++R PP E PA+G A L H+ + Y + +
Sbjct: 188 LLR-------------PPSLAEDPAVGGPRA---------QLTSLLHHGPFLRYTVALTL 225
Query: 196 SVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFLRPLAGLMAGRPAFASHRKYL 255
G+ +P + LV + D AA L+S++ S++ R ++G + A L
Sbjct: 226 INTGYFIPYLHLVAHLQDLDWDPLPAAFLLSVVAISDLVGRVVSGWLG--DAVPGPVTRL 283
Query: 256 FSLALLLNGLTNLVCAASGDFWVLVGYCLAYSVSMSGIGALIFQVLMDIVPMDQFPRALG 315
L L G++ + + LV +AY + + L F VL +++ + LG
Sbjct: 284 LMLWTTLTGVSLALFPVAQAPTALVALAVAYGFTSGALAPLAFSVLPELIGTRRIYCGLG 343
Query: 316 LFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMSSFFLISAA--LFMGGSFYALQKKEQG 373
L +++ + L+ PPL+G L D T N++ F ++ FL+S + L F+ G
Sbjct: 344 LLQMIESIGGLLGPPLSGYLRDVTGNYTASFVVAGAFLLSGSGILLTLPHFFCFSTTTSG 403
Query: 374 KQAVAADALE 383
Q + +AL+
Sbjct: 404 PQDLVTEALD 413
>gi|41327156 solute carrier family 16 (monocarboxylic acid
transporters), member 14 [Homo sapiens]
Length = 510
Score = 130 bits (326), Expect = 3e-30
Identities = 98/410 (23%), Positives = 171/410 (41%), Gaps = 62/410 (15%)
Query: 10 VALSERPLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCFS 69
+ L P + + GCR T ++GG++ SLG V S+++ N+ L+ T G GLG +
Sbjct: 82 ITLIVGPFIGLFINTCGCRQTAIIGGLVNSLGWVLSAYAANVHYLFITFGVAAGLGSGMA 141
Query: 70 FQSSITVLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFLH 129
+ ++ ++G YF +RR LA L++ G G L +L +YL GWR L+ G + L+
Sbjct: 142 YLPAVVMVGRYFQKRRALAQGLSTTGTGFGTFLMTVLLKYLCAEYGWRNAMLIQGAVSLN 201
Query: 130 CCICGAIIRPVATSVAP----ETKECPPPPPETPALGCLAACGRT--------------- 170
C+CGA++RP++ P E P T ++ GRT
Sbjct: 202 LCVCGALMRPLSPGKNPNDPGEKDVRGLPAHSTESVKSTGQQGRTEEKDGGLGNEETLCD 261
Query: 171 IQRHLAFDILRHNTGYC------------------------------------VYILGVM 194
+Q D H C +++ +
Sbjct: 262 LQAQECPDQAGHRKNMCALRILKTVSWLTMRVRKGFEDWYSGYFGTASLFTNRMFVAFIF 321
Query: 195 WSVL---GFPLPQVFLVPYAMWHSVDEQQAAL-LISIIGFSNIFLRPLAGLMAGRPAFAS 250
W++ F +P + L +++ EQ L SII +IF + + G++A P +
Sbjct: 322 WALFAYSSFVIPFIHLPEIVNLYNLSEQNDVFPLTSIIAIVHIFGKVILGVIADLPCISV 381
Query: 251 HRKYLFSLALLLNGLTNLVCAASGDFWVLVGYCLAYSVSMSGIGALIFQVLMDIVPMDQF 310
+L + L+ L+ + + L C S SG +L+ V D+V ++
Sbjct: 382 WNVFLLANFTLV--LSIFILPLMHTYAGLAVICALIGFS-SGYFSLMPVVTEDLVGIEHL 438
Query: 311 PRALGLFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMSSFFLISAALFM 360
A G+ +G++ L+ PP AG + D T + + FY+ + LF+
Sbjct: 439 ANAYGIIICANGISALLGPPFAGWIYDITQKYDFSFYICGLLYMIGILFL 488
>gi|5730045 solute carrier family 16, member 2 [Homo sapiens]
Length = 613
Score = 124 bits (310), Expect = 2e-28
Identities = 92/349 (26%), Positives = 160/349 (45%), Gaps = 17/349 (4%)
Query: 16 PLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCFSFQSSIT 75
P+ SI R GCR+T G +A +G+ SSF+ +LS YFT G + G G F+FQ S+
Sbjct: 233 PIVSIFTDRLGCRITATAGAAVAFIGLHTSSFTSSLSLRYFTYGILFGCGCSFAFQPSLV 292
Query: 76 VLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFLHCCICGA 135
+LG YF RR LAN + S G S+ +P L R L + + TF V +
Sbjct: 293 ILGHYFQRRLGLANGVVSAGSSIFSMSFPFLIRMLGDKIKLAQTFQVLSTFMFVLMLLSL 352
Query: 136 IIRPVATSVAPETKECPPPPPETPALGCLAACGR----TIQRHLAFDILRHNTGYCVYIL 191
RP+ P +TP+ + + ++++ + R T Y ++
Sbjct: 353 TYRPLL-----------PSSQDTPSKRGVRTLHQRFLAQLRKYFNMRVFRQRT-YRIWAF 400
Query: 192 GVMWSVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFLRPLAGLMAGRPAFASH 251
G+ + LG+ +P V L+ Y + ++ +L+ IG ++ R ++G ++
Sbjct: 401 GIAAAALGYFVPYVHLMKYVEEEFSEIKETWVLLVCIGATSGLGRLVSGHISDSIP-GLK 459
Query: 252 RKYLFSLALLLNGLTNLVCAASGDFWVLVGYCLAYSVSMSGIGALIFQVLMDIVPMDQFP 311
+ YL L+ LL GL +++ DF L+ CL + ++ + ++V Q
Sbjct: 460 KIYLQVLSFLLLGLMSMMIPLCRDFGGLIVVCLFLGLCDGFFITIMAPIAFELVGPMQAS 519
Query: 312 RALGLFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMSSFFLISAALFM 360
+A+G + L + PP+AGLL + ++ FY + I A+ +
Sbjct: 520 QAIGYLLGMMALPMIAGPPIAGLLRNCFGDYHVAFYFAGVPPIIGAVIL 568
>gi|18699730 solute carrier family 16, member 10 [Homo sapiens]
Length = 515
Score = 123 bits (309), Expect = 3e-28
Identities = 98/405 (24%), Positives = 177/405 (43%), Gaps = 36/405 (8%)
Query: 16 PLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCFSFQSSIT 75
P+ S+ FGCR T ++G + +G+++SSF ++ LY T G I G F++Q S+
Sbjct: 130 PIVSVFTDLFGCRKTAVVGAAVGFVGLMSSSFVSSIEPLYLTYGIIFACGCSFAYQPSLV 189
Query: 76 VLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFLHCCICGA 135
+LG YF +R L N + + G S+ L PLL R L++++G T V + G
Sbjct: 190 ILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLRVLIDSVGLFYTLRVLCIFMFVLFLAGF 249
Query: 136 IIRPVATSVAPET-----------KECPPPPPETPALGCLAACGRTIQRHLAFDILRHNT 184
RP+ATS + K+ PP + I F + T
Sbjct: 250 TYRPLATSTKDKESGGSGSSLFSRKKFSPP--------------KKIFNFAIFKV----T 291
Query: 185 GYCVYILGVMWSVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFLRPLAGLMAG 244
Y V+ +G+ ++ G+ +P V L+ + DE+ +++ IG ++ R L G +A
Sbjct: 292 AYAVWAVGIPLALFGYFVPYVHLMKHVNERFQDEKNKEVVLMCIGVTSGVGRLLFGRIAD 351
Query: 245 RPAFASHRKYLFSLALLLNGLTNLVCAASGDFWVLVGYCLAYSVSMSGIGALIFQVLMDI 304
+ YL L+ GL +++ F L+ CL + +++ + ++
Sbjct: 352 YVPGVK-KVYLQVLSFFFIGLMSMMIPLCSIFGALIAVCLIMGLFDGCFISIMAPIAFEL 410
Query: 305 VPMDQFPRALGLFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMSSF-FLISAALFMGGS 363
V +A+G + + PP+AGLL D ++ FY++ LI A+
Sbjct: 411 VGAQDVSQAIGFLLGFMSIPMTVGPPIAGLLRDKLGSYDVAFYLAGVPPLIGGAVLCFIP 470
Query: 364 FYALQKKEQGKQAVAADALERDL-----FLEAKDGPGKQRSPEIM 403
+ +K+ + + + +E+ L L + G K+ S I+
Sbjct: 471 WIHSKKQREISKTTGKEKMEKMLENQNSLLSSSSGMFKKESDSII 515
>gi|40789261 solute carrier family 16, member 6 [Homo sapiens]
Length = 523
Score = 108 bits (271), Expect = 8e-24
Identities = 55/125 (44%), Positives = 78/125 (62%)
Query: 16 PLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCFSFQSSIT 75
PL ++L RFG R+ VMLGG+L S GMVA+SFS +S +Y G I+GLG CFSF ++T
Sbjct: 79 PLATVLSNRFGHRLVVMLGGLLVSTGMVAASFSQEVSHMYVAIGIISGLGYCFSFLPTVT 138
Query: 76 VLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFLHCCICGA 135
+L YF +RR + A+AS G + + L E +GWR + L G + L+ I GA
Sbjct: 139 ILSQYFGKRRSIVTAVASTGECFAVFAFAPAIMALKERIGWRYSLLFVGLLQLNIVIFGA 198
Query: 136 IIRPV 140
++RP+
Sbjct: 199 LLRPI 203
Score = 77.8 bits (190), Expect = 2e-14
Identities = 48/186 (25%), Positives = 95/186 (51%), Gaps = 5/186 (2%)
Query: 175 LAFDILRHNTGYCVYILGVMWSVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIF 234
L F IL+ + C + G +++ LGF P ++++P + +D+ +AA L+S + + +F
Sbjct: 284 LDFSILKEKSFICYALFG-LFATLGFFAPSLYIIPLGISLGIDQDRAAFLLSTMAIAEVF 342
Query: 235 LRPLAGLMAGRPAFASHRKYLFSLALLLNGLTNLVCAASGDFWVLVGYCLAYSVSMSGIG 294
R AG + R + Y+ + ++L ++ + +FW L+ + + + IG
Sbjct: 343 GRIGAGFVLNREPI--RKIYIELICVILLTVSLFAFTFATEFWGLMSCSIFFGFMVGTIG 400
Query: 295 ALIFQVLM--DIVPMDQFPRALGLFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMSSFF 352
+L D+V +++ A G++ + +A L PPLAGLL+D + +S FY +
Sbjct: 401 GTHIPLLAEDDVVGIEKMSSAAGVYIFIQSIAGLAGPPLAGLLVDQSKIYSRAFYSCAAG 460
Query: 353 LISAAL 358
+ AA+
Sbjct: 461 MALAAV 466
>gi|34916028 solute carrier family 16 (monocarboxylic acid
transporters), member 9 [Homo sapiens]
Length = 509
Score = 95.9 bits (237), Expect = 7e-20
Identities = 50/144 (34%), Positives = 81/144 (56%)
Query: 10 VALSERPLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCFS 69
V L P+CS+ V FG R + G + + G++ SSF+ N+ L+F+ G + GLG
Sbjct: 61 VGLLASPVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLL 120
Query: 70 FQSSITVLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFLH 129
+ +++T+ YF RR LA L S G S+G+ ++ L R L+E G G L+ G + L+
Sbjct: 121 YTATVTITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALN 180
Query: 130 CCICGAIIRPVATSVAPETKECPP 153
CG+++RP+ +S P K+ P
Sbjct: 181 ILACGSLMRPLQSSDCPLPKKIAP 204
Score = 48.5 bits (114), Expect = 1e-05
Identities = 44/190 (23%), Positives = 83/190 (43%), Gaps = 13/190 (6%)
Query: 167 CGRTIQRHLAFDILRHNTGYCVYILGVMWSVLGFPLPQVFLVPYAMWHSVDEQQAAL-LI 225
CG T+ + ++ ++I +++ + GFP P + + A +V E++ + LI
Sbjct: 294 CGETVA------LFKNKVFSALFIAILLFDIGGFP-PSLLMEDVARSSNVKEEEFIMPLI 346
Query: 226 SIIGFSNIFLRPLAGLMAGRPAFASHRKYLFSLALLLNGLTNLVCAAS-GDFWVLVGYCL 284
SIIG + L G++A + YL+ L++ GL +CA +V +
Sbjct: 347 SIIGIMTAVGKLLLGILADFKWI--NTLYLYVATLIIMGLA--LCAIPFAKSYVTLALLS 402
Query: 285 AYSVSMSGIGALIFQVLMDIVPMDQFPRALGLFTVLDGLAFLISPPLAGLLLDATNNFSY 344
++G ++ V V +++ A G+ GL + PP+ G D T +
Sbjct: 403 GILGFLTGNWSIFPYVTTKTVGIEKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDI 462
Query: 345 VFYMSSFFLI 354
FY S F ++
Sbjct: 463 AFYFSGFCVL 472
>gi|4759114 solute carrier family 16, member 4 [Homo sapiens]
Length = 487
Score = 77.8 bits (190), Expect = 2e-14
Identities = 56/188 (29%), Positives = 93/188 (49%), Gaps = 10/188 (5%)
Query: 177 FDI-LRHNTGYCVYILGVMWSVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFL 235
FDI L N + ++ + S L + +P LV A +D A+ L+S+ G
Sbjct: 291 FDISLFRNPFFYIFTWSFLLSQLAYFIPTFHLVARAKTLGIDIMDASYLVSVAGILETVS 350
Query: 236 RPLAGLMAGR---PAFASHRKYLFSLALLLNGLTNLVCAASGDFWVLVGYCLAYSVSMSG 292
+ ++G +A + + H+ YL +L G+TNL+ + F +L+ Y + +++ G
Sbjct: 351 QIISGWVADQNWIKKYHYHKSYL-----ILCGITNLLAPLATTFPLLMTYTICFAIFAGG 405
Query: 293 IGALIFQVLMDIVPMDQFPRALGLFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMSSF- 351
ALI VL+D+ R LGL + G+A L PP+AG L D T ++ FY S
Sbjct: 406 YLALILPVLVDLCRNSTVNRFLGLASFFAGMAVLSGPPIAGWLYDYTQTYNGSFYFSGIC 465
Query: 352 FLISAALF 359
+L+S+ F
Sbjct: 466 YLLSSVSF 473
Score = 68.6 bits (166), Expect = 1e-11
Identities = 38/125 (30%), Positives = 67/125 (53%), Gaps = 1/125 (0%)
Query: 16 PLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCFSFQSSIT 75
PL +I+ G + T +LG + + G + SS++ ++ L T G + GLG F +Q +
Sbjct: 75 PLVAIICDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLLPGLGSAFLYQVAAV 134
Query: 76 VLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFLHCCICGA 135
V YF +R L+ A+A G+ L L P +++L++ W G ++FG I L+
Sbjct: 135 VTTKYFKKRLALSTAIARSGMGLTFLLAP-FTKFLIDLYDWTGALILFGAIALNLVPSSM 193
Query: 136 IIRPV 140
++RP+
Sbjct: 194 LLRPI 198
>gi|215272392 solute carrier family 18 (vesicular monoamine), member
1 isoform c [Homo sapiens]
Length = 472
Score = 37.4 bits (85), Expect = 0.028
Identities = 37/150 (24%), Positives = 66/150 (44%), Gaps = 10/150 (6%)
Query: 9 LVALSERPLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCF 68
++ L P L R G + + G V+ L V +FS + L F A + G+G F
Sbjct: 148 VMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTYT-LLFVARTLQGIGSSF 206
Query: 69 SFQSSITVLGFYFV----RRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFG 124
S + + +L + R R + AL G++LG+ + + E +G FL+
Sbjct: 207 SSVAGLGMLASVYTDDHERGRAMGTALG--GLALGLLVGAPFGSVMYEFVGKSAPFLILA 264
Query: 125 GI-FLHCCICGAIIRPVATSVAPETKECPP 153
+ L + I++P + V+PE+ + P
Sbjct: 265 FLALLDGALQLCILQP--SKVSPESAKGTP 292
>gi|215272390 solute carrier family 18 (vesicular monoamine), member
1 isoform b [Homo sapiens]
Length = 493
Score = 37.4 bits (85), Expect = 0.028
Identities = 37/150 (24%), Positives = 66/150 (44%), Gaps = 10/150 (6%)
Query: 9 LVALSERPLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCF 68
++ L P L R G + + G V+ L V +FS + L F A + G+G F
Sbjct: 148 VMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTYT-LLFVARTLQGIGSSF 206
Query: 69 SFQSSITVLGFYFV----RRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFG 124
S + + +L + R R + AL G++LG+ + + E +G FL+
Sbjct: 207 SSVAGLGMLASVYTDDHERGRAMGTALG--GLALGLLVGAPFGSVMYEFVGKSAPFLILA 264
Query: 125 GI-FLHCCICGAIIRPVATSVAPETKECPP 153
+ L + I++P + V+PE+ + P
Sbjct: 265 FLALLDGALQLCILQP--SKVSPESAKGTP 292
>gi|208879454 solute carrier family 18 (vesicular monoamine), member
1 isoform a [Homo sapiens]
Length = 525
Score = 37.4 bits (85), Expect = 0.028
Identities = 37/150 (24%), Positives = 66/150 (44%), Gaps = 10/150 (6%)
Query: 9 LVALSERPLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCF 68
++ L P L R G + + G V+ L V +FS + L F A + G+G F
Sbjct: 148 VMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTYT-LLFVARTLQGIGSSF 206
Query: 69 SFQSSITVLGFYFV----RRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFG 124
S + + +L + R R + AL G++LG+ + + E +G FL+
Sbjct: 207 SSVAGLGMLASVYTDDHERGRAMGTALG--GLALGLLVGAPFGSVMYEFVGKSAPFLILA 264
Query: 125 GI-FLHCCICGAIIRPVATSVAPETKECPP 153
+ L + I++P + V+PE+ + P
Sbjct: 265 FLALLDGALQLCILQP--SKVSPESAKGTP 292
>gi|4506987 solute carrier family 18 (vesicular monoamine), member 1
isoform a [Homo sapiens]
Length = 525
Score = 37.4 bits (85), Expect = 0.028
Identities = 37/150 (24%), Positives = 66/150 (44%), Gaps = 10/150 (6%)
Query: 9 LVALSERPLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCF 68
++ L P L R G + + G V+ L V +FS + L F A + G+G F
Sbjct: 148 VMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTYT-LLFVARTLQGIGSSF 206
Query: 69 SFQSSITVLGFYFV----RRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFG 124
S + + +L + R R + AL G++LG+ + + E +G FL+
Sbjct: 207 SSVAGLGMLASVYTDDHERGRAMGTALG--GLALGLLVGAPFGSVMYEFVGKSAPFLILA 264
Query: 125 GI-FLHCCICGAIIRPVATSVAPETKECPP 153
+ L + I++P + V+PE+ + P
Sbjct: 265 FLALLDGALQLCILQP--SKVSPESAKGTP 292
>gi|148743791 solute carrier family 17 (sodium phosphate), member 3
isoform a [Homo sapiens]
Length = 498
Score = 35.4 bits (80), Expect = 0.11
Identities = 15/48 (31%), Positives = 26/48 (54%)
Query: 90 ALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFLHCCICGAII 137
++A G+ LG L+ ++ E LGW F +FGG+ CC+ ++
Sbjct: 204 SIALSGMLLGCFTAILIGGFISETLGWPFVFYIFGGVGCVCCLLWFVV 251
>gi|148728191 solute carrier family 17 (sodium phosphate), member 3
isoform b [Homo sapiens]
Length = 420
Score = 35.4 bits (80), Expect = 0.11
Identities = 15/48 (31%), Positives = 26/48 (54%)
Query: 90 ALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFLHCCICGAII 137
++A G+ LG L+ ++ E LGW F +FGG+ CC+ ++
Sbjct: 126 SIALSGMLLGCFTAILIGGFISETLGWPFVFYIFGGVGCVCCLLWFVV 173
>gi|12232393 major facilitator superfamily domain containing 1 [Homo
sapiens]
Length = 465
Score = 35.4 bits (80), Expect = 0.11
Identities = 42/199 (21%), Positives = 88/199 (44%), Gaps = 15/199 (7%)
Query: 186 YCVYILGVMWSVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFLRPLAGLMAGR 245
+ ++I+ V + V FP + V + Q A+ + S++ + + P+ GL+ +
Sbjct: 267 WLIFIICVCYYVAVFPFIGLGKVFFTEKFGFSSQAASAINSVVYVISAPMSPVFGLLVDK 326
Query: 246 PAFASHRKYLFSLALLLNGLTNLVCAASGDFWVLVGYCLAYSVSMSGIGALIFQVLMDIV 305
+ ++ L + L + + A + + CL +S S + ++ ++ +V
Sbjct: 327 TG----KNIIWVLCAVAATLVSHMMLAFTMWNPWIAMCLL-GLSYSLLACALWPMVAFVV 381
Query: 306 PMDQFPRALGLFTVLDGLAFLISPPLAGLLLDATNN-FSYVFYMS--SFFLISAALF--- 359
P Q A G + L I +AG++LD+ F VF+++ S L+S L
Sbjct: 382 PEHQLGTAYGFMQSIQNLGLAIISIIAGMILDSRGYLFLEVFFIACVSLSLLSVVLLYLV 441
Query: 360 ---MGGSF-YALQKKEQGK 374
GG+ Y+ +++E+ K
Sbjct: 442 NRAQGGNLNYSARQREEIK 460
>gi|42476325 solute carrier family 18 (vesicular monoamine), member
2 [Homo sapiens]
Length = 514
Score = 33.9 bits (76), Expect = 0.31
Identities = 33/147 (22%), Positives = 63/147 (42%), Gaps = 6/147 (4%)
Query: 10 VALSERPLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCFS 69
V L P +L R G + + G + + + +FS + + L A + G+G S
Sbjct: 141 VQLITNPFIGLLTNRIGYPIPIFAGFCIMFVSTIMFAFSSSYAFLLI-ARSLQGIGSSCS 199
Query: 70 FQSSITVLGFYFVRRRVLANAL--ASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGG-I 126
+ + +L + N + A G+++G+ + P L E +G FLV +
Sbjct: 200 SVAGMGMLASVYTDDEERGNVMGIALGGLAMGVLVGPPFGSVLYEFVGKTAPFLVLAALV 259
Query: 127 FLHCCICGAIIRPVATSVAPETKECPP 153
L I +++P + V PE+++ P
Sbjct: 260 LLDGAIQLFVLQP--SRVQPESQKGTP 284
>gi|122937193 DNB5 [Homo sapiens]
Length = 748
Score = 33.1 bits (74), Expect = 0.53
Identities = 31/133 (23%), Positives = 56/133 (42%), Gaps = 11/133 (8%)
Query: 146 PETKEC----PPPPPETPALGCLAACGRTIQRHLAFDILRHNTGYCVYILGVMWSVLGFP 201
P+ ++C PPPPP TP L G + ++L + C+ + G+ +S +
Sbjct: 50 PKRRKCIRPSPPPPPNTPCPLELVDFGDLHPQRSFRELLFNG---CI-LFGIEFS---YA 102
Query: 202 LPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFLRPLAGLMAGRPAFASHRKYLFSLALL 261
+ ++ P + + +Q +L+ I L+PL G + R R+ F L L
Sbjct: 103 METAYVTPVLLQMGLPDQLYSLVWFISPILGFLLQPLLGAWSDRCTSRFGRRRPFILVLA 162
Query: 262 LNGLTNLVCAASG 274
+ L L +G
Sbjct: 163 IGALLGLSLLLNG 175
>gi|38348211 golgi transport 1 homolog A [Homo sapiens]
Length = 132
Score = 32.7 bits (73), Expect = 0.69
Identities = 29/106 (27%), Positives = 46/106 (43%), Gaps = 15/106 (14%)
Query: 22 VGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCFSFQSSITVLGFYF 81
VG G + +L G L V +F + L F+TGL + + + F+F
Sbjct: 12 VGITGFGIFFILFGTLLYFDSVLLAFGNLL--------FLTGLSLIIGLRKTFW---FFF 60
Query: 82 VRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIF 127
R ++ + GV + + WPLL + LE G+ F +F G F
Sbjct: 61 QRHKLKGTSFLLGGVVIVLLRWPLLGMF-LETYGF---FSLFKGFF 102
>gi|4885441 solute carrier family 17 (sodium phosphate), member 4
[Homo sapiens]
Length = 497
Score = 32.3 bits (72), Expect = 0.91
Identities = 31/114 (27%), Positives = 46/114 (40%), Gaps = 4/114 (3%)
Query: 21 LVGRFGCRVTVMLGGVLASLGMVASSFSHNLS-QLYFTAGFITGLG--MCFSFQSSITVL 77
+ G FG + V G ++S + + N L + G+ M + Q SI V
Sbjct: 131 VAGIFGAKYVVGAGLFISSFLTLFIPLAANAGVALLIVLRIVQGIAQVMVLTGQYSIWVK 190
Query: 78 GFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFLHCC 131
+ R L +A G LG + L L + +GW F +FGGI CC
Sbjct: 191 WAPPLERSQLTT-IAGSGSMLGSFIVLLAGGLLCQTIGWPYVFYIFGGIGCACC 243
>gi|148664184 solute carrier family 22, member 10 [Homo sapiens]
Length = 541
Score = 31.6 bits (70), Expect = 1.5
Identities = 39/154 (25%), Positives = 60/154 (38%), Gaps = 26/154 (16%)
Query: 10 VALSERPLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCFS 69
VAL R L + + G R++ +L L L ++A++F Q A G+G +
Sbjct: 388 VALIVRCLALLTLNHMGRRISQILFMFLVGLSILANTFVPKEMQTLRVALACLGIGCSAA 447
Query: 70 FQSSITVLGFYFVR-----RRVLANALASMGVSLGITLWPLLS--RYLLENLGW--RGTF 120
SS+ V +F+ R A+ + +G L PLL L W G F
Sbjct: 448 TFSSVAV---HFIELIPTVLRARASGIDLTASRIGAALAPLLMTLTVFFTTLPWIIYGIF 504
Query: 121 LVFGGIFLHCCICGAIIRPVATSVAPETKECPPP 154
+ GG+ + + PETK P P
Sbjct: 505 PIIGGLIVF--------------LLPETKNLPLP 524
>gi|52353332 olfactory receptor, family 52, subfamily D, member 1
[Homo sapiens]
Length = 318
Score = 31.6 bits (70), Expect = 1.5
Identities = 13/39 (33%), Positives = 21/39 (53%)
Query: 265 LTNLVCAASGDFWVLVGYCLAYSVSMSGIGALIFQVLMD 303
LT + + FW+ + +C Y V++ G ALI + MD
Sbjct: 17 LTGIPGLEAAHFWIAIPFCAMYLVALVGNAALILVIAMD 55
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.328 0.141 0.452
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,972,738
Number of Sequences: 37866
Number of extensions: 831171
Number of successful extensions: 5455
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 5399
Number of HSP's gapped (non-prelim): 55
length of query: 453
length of database: 18,247,518
effective HSP length: 106
effective length of query: 347
effective length of database: 14,233,722
effective search space: 4939101534
effective search space used: 4939101534
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.