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Search of human proteins with 169217736
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|169217736 PREDICTED: similar to PDZ domain containing 1
[Homo sapiens]
(227 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|169217736 PREDICTED: similar to PDZ domain containing 1 [Homo... 467 e-132
gi|21361142 PDZ domain containing 1 [Homo sapiens] 351 3e-97
gi|194018553 solute carrier family 9 isoform 3 regulator 2 isofo... 87 9e-18
gi|71897229 solute carrier family 9 isoform 3 regulator 2 isofor... 87 9e-18
gi|4759140 sodium/hydrogen exchanger regulatory factor 1 [Homo s... 82 3e-16
gi|21630285 PDZ domain containing 3 [Homo sapiens] 60 1e-09
gi|4557529 post-synaptic density protein 95 isoform 1 [Homo sapi... 60 2e-09
gi|192447426 post-synaptic density protein 95 isoform 2 [Homo sa... 60 2e-09
gi|119943106 synapse-associated protein 102 isoform a [Homo sapi... 57 1e-08
gi|31742501 sorting nexin family member 27 [Homo sapiens] 57 2e-08
gi|218156338 chapsyn-110 isoform 1 [Homo sapiens] 56 3e-08
gi|91199538 chapsyn-110 isoform 2 [Homo sapiens] 56 3e-08
gi|119943108 synapse-associated protein 102 isoform b [Homo sapi... 53 2e-07
gi|148539628 discs, large homolog 1 isoform 1 [Homo sapiens] 53 2e-07
gi|148539578 discs, large homolog 1 isoform 2 [Homo sapiens] 53 2e-07
gi|223278403 glutamate receptor, ionotropic, delta 2 (Grid2) int... 51 7e-07
gi|218156340 chapsyn-110 isoform 3 [Homo sapiens] 51 7e-07
gi|203097003 Rho GTPase activating protein 21 [Homo sapiens] 49 3e-06
gi|45120119 microtubule associated serine/threonine kinase 1 [Ho... 47 1e-05
gi|148612825 Rap GTPase interactor [Homo sapiens] 47 1e-05
gi|116875765 tight junction protein 1 isoform b [Homo sapiens] 47 2e-05
gi|116875767 tight junction protein 1 isoform a [Homo sapiens] 47 2e-05
gi|224458284 Rho GTPase activating protein 23 [Homo sapiens] 44 9e-05
gi|4506509 regulator of G-protein signalling 12 isoform 2 [Homo ... 44 9e-05
gi|38327601 regulator of G-protein signalling 12 isoform 1 [Homo... 44 9e-05
gi|47933392 cytohesin 1 interacting protein [Homo sapiens] 44 1e-04
gi|11545920 lin-7 homolog B [Homo sapiens] 44 1e-04
gi|18375650 protein tyrosine phosphatase, non-receptor type 13 i... 42 3e-04
gi|18375648 protein tyrosine phosphatase, non-receptor type 13 i... 42 3e-04
gi|18375646 protein tyrosine phosphatase, non-receptor type 13 i... 42 3e-04
>gi|169217736 PREDICTED: similar to PDZ domain containing 1 [Homo
sapiens]
Length = 227
Score = 467 bits (1201), Expect = e-132
Identities = 227/227 (100%), Positives = 227/227 (100%)
Query: 1 MSCDCQIQLAHFSPFLYYQSQELPNGSVKEAPAPTPTSLEVSSPPDTTEEEDHKPKLCRL 60
MSCDCQIQLAHFSPFLYYQSQELPNGSVKEAPAPTPTSLEVSSPPDTTEEEDHKPKLCRL
Sbjct: 1 MSCDCQIQLAHFSPFLYYQSQELPNGSVKEAPAPTPTSLEVSSPPDTTEEEDHKPKLCRL 60
Query: 61 AKGENGYGFHLNAIRGLPGSFIKEVQKGGPADLAGLEDEDVIIEVNGVNVLDEPYEKVVD 120
AKGENGYGFHLNAIRGLPGSFIKEVQKGGPADLAGLEDEDVIIEVNGVNVLDEPYEKVVD
Sbjct: 61 AKGENGYGFHLNAIRGLPGSFIKEVQKGGPADLAGLEDEDVIIEVNGVNVLDEPYEKVVD 120
Query: 121 RIQSSGKNVTLLVCGKKAYDYFQAKKIPIVSSLADPLDTPPDSKEGIVVESNHDSHMAKE 180
RIQSSGKNVTLLVCGKKAYDYFQAKKIPIVSSLADPLDTPPDSKEGIVVESNHDSHMAKE
Sbjct: 121 RIQSSGKNVTLLVCGKKAYDYFQAKKIPIVSSLADPLDTPPDSKEGIVVESNHDSHMAKE 180
Query: 181 RIIHSDLNASCDRIRFPNSIKNNIDGSLQRCRFLPWSILTITYYFKK 227
RIIHSDLNASCDRIRFPNSIKNNIDGSLQRCRFLPWSILTITYYFKK
Sbjct: 181 RIIHSDLNASCDRIRFPNSIKNNIDGSLQRCRFLPWSILTITYYFKK 227
>gi|21361142 PDZ domain containing 1 [Homo sapiens]
Length = 519
Score = 351 bits (901), Expect = 3e-97
Identities = 173/178 (97%), Positives = 174/178 (97%)
Query: 4 DCQIQLAHFSPFLYYQSQELPNGSVKEAPAPTPTSLEVSSPPDTTEEEDHKPKLCRLAKG 63
D +LAHFSPFLYYQSQELPNGSVKEAPAPTPTSLEVSSPPDTTEE DHKPKLCRLAKG
Sbjct: 325 DNMYRLAHFSPFLYYQSQELPNGSVKEAPAPTPTSLEVSSPPDTTEEVDHKPKLCRLAKG 384
Query: 64 ENGYGFHLNAIRGLPGSFIKEVQKGGPADLAGLEDEDVIIEVNGVNVLDEPYEKVVDRIQ 123
ENGYGFHLNAIRGLPGSFIKEVQKGGPADLAGLEDEDVIIEVNGVNVLDEPYEKVVDRIQ
Sbjct: 385 ENGYGFHLNAIRGLPGSFIKEVQKGGPADLAGLEDEDVIIEVNGVNVLDEPYEKVVDRIQ 444
Query: 124 SSGKNVTLLVCGKKAYDYFQAKKIPIVSSLADPLDTPPDSKEGIVVESNHDSHMAKER 181
SSGKNVTLLVCGKKAYDYFQAKKIPIVSSLADPLDTPPDSKEGIVVESNHDSHMAKER
Sbjct: 445 SSGKNVTLLVCGKKAYDYFQAKKIPIVSSLADPLDTPPDSKEGIVVESNHDSHMAKER 502
Score = 77.4 bits (189), Expect = 9e-15
Identities = 40/119 (33%), Positives = 66/119 (55%), Gaps = 11/119 (9%)
Query: 53 HKPKLCRLAKGENGYGFHLNAIRGLPGSFIKEVQKGGPADLAGLEDEDVIIEVNGVNVLD 112
H+P++ + KG NGYGF+L A G IK++ G PA+ AGL++ D+++ VNG +V
Sbjct: 239 HQPRIVEMKKGSNGYGFYLRAGSEQKGQIIKDIDSGSPAEEAGLKNNDLVVAVNGESVET 298
Query: 113 EPYEKVVDRIQSSGKNVTLLVCGKKA-----------YDYFQAKKIPIVSSLADPLDTP 160
++ VV+ I+ G +LLV K+ + Y+Q++++P S P TP
Sbjct: 299 LDHDSVVEMIRKGGDQTSLLVVDKETDNMYRLAHFSPFLYYQSQELPNGSVKEAPAPTP 357
Score = 67.4 bits (163), Expect = 1e-11
Identities = 35/87 (40%), Positives = 54/87 (62%), Gaps = 1/87 (1%)
Query: 55 PKLCRLAKGEN-GYGFHLNAIRGLPGSFIKEVQKGGPADLAGLEDEDVIIEVNGVNVLDE 113
P+ C+L+K E YGF L + G ++ V+K PA+ AGL+D D ++ +NGV V E
Sbjct: 7 PRECKLSKQEGQNYGFFLRIEKDTEGHLVRVVEKCSPAEKAGLQDGDRVLRINGVFVDKE 66
Query: 114 PYEKVVDRIQSSGKNVTLLVCGKKAYD 140
+ +VVD ++ SG +VTLLV +Y+
Sbjct: 67 EHMQVVDLVRKSGNSVTLLVLDGDSYE 93
Score = 65.9 bits (159), Expect = 3e-11
Identities = 32/84 (38%), Positives = 51/84 (60%)
Query: 54 KPKLCRLAKGENGYGFHLNAIRGLPGSFIKEVQKGGPADLAGLEDEDVIIEVNGVNVLDE 113
+P+LC L K YGF L ++G G ++ ++ G A AG+ +D +IEVNG NV D
Sbjct: 132 QPRLCYLVKEGGSYGFSLKTVQGKKGVYMTDITPQGVAMRAGVLADDHLIEVNGENVEDA 191
Query: 114 PYEKVVDRIQSSGKNVTLLVCGKK 137
+E+VV++++ SG V L+ K+
Sbjct: 192 SHEEVVEKVKKSGSRVMFLLVDKE 215
>gi|194018553 solute carrier family 9 isoform 3 regulator 2 isoform
a [Homo sapiens]
Length = 337
Score = 87.4 bits (215), Expect = 9e-18
Identities = 47/136 (34%), Positives = 73/136 (53%), Gaps = 4/136 (2%)
Query: 51 EDHKPKLCRLAKGENGYGFHLNAIRGLPGSFIKEVQKGGPADLAGLEDEDVIIEVNGVNV 110
E +P+LCRL +GE GYGFHL+ +G G FI+ V+ G PA+ A L D ++EVNGVNV
Sbjct: 5 EPLRPRLCRLVRGEQGYGFHLHGEKGRRGQFIRRVEPGSPAEAAALRAGDRLVEVNGVNV 64
Query: 111 LDEPYEKVVDRIQSSGKNVTLLVCGKKAYDYFQAKKIPIVSSLAD----PLDTPPDSKEG 166
E + +VV RI++ LLV ++ + + +++ +A P P + K
Sbjct: 65 EGETHHQVVQRIKAVEGQTRLLVVDQETDEELRRRQLTCTEEMAQRGLPPAHDPWEPKPD 124
Query: 167 IVVESNHDSHMAKERI 182
+H S K+ +
Sbjct: 125 WAHTGSHSSEAGKKDV 140
Score = 73.9 bits (180), Expect = 1e-13
Identities = 39/108 (36%), Positives = 62/108 (57%), Gaps = 1/108 (0%)
Query: 54 KPKLCRLAKGENGYGFHLNAIRGLPGSFIKEVQKGGPADLAGLEDEDVIIEVNGVNVLDE 113
+P+LC L KG GYGF+L++ + PG +I+ V G PA +GL +D +IEVNG NV
Sbjct: 148 RPRLCHLRKGPQGYGFNLHSDKSRPGQYIRSVDPGSPAARSGLRAQDRLIEVNGQNVEGL 207
Query: 114 PYEKVVDRIQSSGKNVTLLVCGKKAYDYFQAKKI-PIVSSLADPLDTP 160
+ +VV I++ LLV + ++F+ ++ P + PL +P
Sbjct: 208 RHAEVVASIKAREDEARLLVVDPETDEHFKRLRVTPTEEHVEGPLPSP 255
>gi|71897229 solute carrier family 9 isoform 3 regulator 2 isoform b
[Homo sapiens]
Length = 326
Score = 87.4 bits (215), Expect = 9e-18
Identities = 47/136 (34%), Positives = 73/136 (53%), Gaps = 4/136 (2%)
Query: 51 EDHKPKLCRLAKGENGYGFHLNAIRGLPGSFIKEVQKGGPADLAGLEDEDVIIEVNGVNV 110
E +P+LCRL +GE GYGFHL+ +G G FI+ V+ G PA+ A L D ++EVNGVNV
Sbjct: 5 EPLRPRLCRLVRGEQGYGFHLHGEKGRRGQFIRRVEPGSPAEAAALRAGDRLVEVNGVNV 64
Query: 111 LDEPYEKVVDRIQSSGKNVTLLVCGKKAYDYFQAKKIPIVSSLAD----PLDTPPDSKEG 166
E + +VV RI++ LLV ++ + + +++ +A P P + K
Sbjct: 65 EGETHHQVVQRIKAVEGQTRLLVVDQETDEELRRRQLTCTEEMAQRGLPPAHDPWEPKPD 124
Query: 167 IVVESNHDSHMAKERI 182
+H S K+ +
Sbjct: 125 WAHTGSHSSEAGKKDV 140
Score = 73.9 bits (180), Expect = 1e-13
Identities = 39/108 (36%), Positives = 62/108 (57%), Gaps = 1/108 (0%)
Query: 54 KPKLCRLAKGENGYGFHLNAIRGLPGSFIKEVQKGGPADLAGLEDEDVIIEVNGVNVLDE 113
+P+LC L KG GYGF+L++ + PG +I+ V G PA +GL +D +IEVNG NV
Sbjct: 148 RPRLCHLRKGPQGYGFNLHSDKSRPGQYIRSVDPGSPAARSGLRAQDRLIEVNGQNVEGL 207
Query: 114 PYEKVVDRIQSSGKNVTLLVCGKKAYDYFQAKKI-PIVSSLADPLDTP 160
+ +VV I++ LLV + ++F+ ++ P + PL +P
Sbjct: 208 RHAEVVASIKAREDEARLLVVDPETDEHFKRLRVTPTEEHVEGPLPSP 255
>gi|4759140 sodium/hydrogen exchanger regulatory factor 1 [Homo
sapiens]
Length = 358
Score = 82.4 bits (202), Expect = 3e-16
Identities = 47/147 (31%), Positives = 79/147 (53%), Gaps = 5/147 (3%)
Query: 19 QSQELPNGSVKEAPAPTPTSLEVSSPPDTT----EEEDHKPKLCRLAKGENGYGFHLNAI 74
++QE P + A A + + P + E+ + +P+LC + KG +GYGF+L++
Sbjct: 112 RAQEAPGQAEPPAAAEVQGAGNENEPREADKSHPEQRELRPRLCTMKKGPSGYGFNLHSD 171
Query: 75 RGLPGSFIKEVQKGGPADLAGLEDEDVIIEVNGVNVLDEPYEKVVDRIQSSGKNVTLLVC 134
+ PG FI+ V PA+ +GL +D I+EVNGV + + + VV I++ G LLV
Sbjct: 172 KSKPGQFIRSVDPDSPAEASGLRAQDRIVEVNGVCMEGKQHGDVVSAIRAGGDETKLLVV 231
Query: 135 GKKAYDYF-QAKKIPIVSSLADPLDTP 160
++ ++F + + IP L PL P
Sbjct: 232 DRETDEFFKKCRVIPSQEHLNGPLPVP 258
Score = 79.3 bits (194), Expect = 2e-15
Identities = 43/116 (37%), Positives = 65/116 (56%)
Query: 55 PKLCRLAKGENGYGFHLNAIRGLPGSFIKEVQKGGPADLAGLEDEDVIIEVNGVNVLDEP 114
P+LC L KG NGYGFHL+ +G G +I+ V+ G PA+ AGL D ++EVNG NV E
Sbjct: 12 PRLCCLEKGPNGYGFHLHGEKGKLGQYIRLVEPGSPAEKAGLLAGDRLVEVNGENVEKET 71
Query: 115 YEKVVDRIQSSGKNVTLLVCGKKAYDYFQAKKIPIVSSLADPLDTPPDSKEGIVVE 170
+++VV RI+++ V LLV + + Q + + L + P ++ E
Sbjct: 72 HQQVVSRIRAALNAVRLLVVDPETDEQLQKLGVQVREELLRAQEAPGQAEPPAAAE 127
>gi|21630285 PDZ domain containing 3 [Homo sapiens]
Length = 491
Score = 60.5 bits (145), Expect = 1e-09
Identities = 42/127 (33%), Positives = 63/127 (49%), Gaps = 5/127 (3%)
Query: 54 KPKLCRLAKGENGYGFHLNAIRGL---PGSFIKEVQKGGPADLAGLEDEDVIIEVNGVNV 110
KP+ L KG G+GF L +GL PG F+ EV G PA AG++ D ++ V G +V
Sbjct: 246 KPRCLHLEKGPQGFGFLLREEKGLDGRPGQFLWEVDPGLPAKKAGMQAGDRLVAVAGESV 305
Query: 111 LDEPYEKVVDRIQSSGKNVTLLVCGKKAYDYFQAKKIPIVSSL--ADPLDTPPDSKEGIV 168
+E+ V RIQ G V+L V +A +F ++ + L + +P S +
Sbjct: 306 EGLGHEETVSRIQGQGSCVSLTVVDPEADRFFSMVRLSPLLFLENTEAPASPQGSSSASL 365
Query: 169 VESNHDS 175
VE+ S
Sbjct: 366 VETEDPS 372
Score = 55.1 bits (131), Expect = 5e-08
Identities = 34/93 (36%), Positives = 48/93 (51%), Gaps = 1/93 (1%)
Query: 54 KPKLCRLAKGEN-GYGFHLNAIRGLPGSFIKEVQKGGPADLAGLEDEDVIIEVNGVNVLD 112
+P+ C L+K E +GFHL G G + V G A GL++ D I+ VN V
Sbjct: 46 RPRFCLLSKEEGKSFGFHLQQELGRAGHVVCRVDPGTSAQRQGLQEGDRILAVNNDVVEH 105
Query: 113 EPYEKVVDRIQSSGKNVTLLVCGKKAYDYFQAK 145
E Y VV RI++S V L V + A+D +A+
Sbjct: 106 EDYAVVVRRIRASSPRVLLTVLARHAHDVARAQ 138
Score = 50.4 bits (119), Expect = 1e-06
Identities = 37/110 (33%), Positives = 51/110 (46%), Gaps = 15/110 (13%)
Query: 9 LAHFSPFLYYQSQELP-------NGSVKEAPAPTPTSLEVSSPPDTTEEEDHKPKLCRLA 61
+ SP L+ ++ E P + S+ E P+ V S P + + C L
Sbjct: 339 MVRLSPLLFLENTEAPASPQGSSSASLVETEDPSLEDTSVPSVPLGSRQ-------CFLY 391
Query: 62 KGENG-YGFHLNAIRGLPGSFIKEVQKGGPADLAGLEDEDVIIEVNGVNV 110
G G YGF L+ + P FI +V GG A AGL+ DVI+EVNG V
Sbjct: 392 PGPGGSYGFRLSCVASGPRLFISQVTPGGSAARAGLQVGDVILEVNGYPV 441
Score = 50.1 bits (118), Expect = 2e-06
Identities = 31/102 (30%), Positives = 50/102 (49%), Gaps = 16/102 (15%)
Query: 54 KPKLCRLAKGENGYGFHLNAIRGLPGSFIKEVQKGGPADLAGLEDEDVIIEVNGVNVLDE 113
+P+LC + K E G+GF + G G F + GG A+ AG+ ++EVNG
Sbjct: 154 RPRLCHIVKDEGGFGFSVT--HGNQGPFWLVLSTGGAAERAGVPPGARLLEVNG------ 205
Query: 114 PYEKVVDRIQSSGKNVTLLVCGKKAYDYFQAKKIPIVSSLAD 155
+ SG+ VTLLV G + + + +P+ + LA+
Sbjct: 206 --------LWQSGQQVTLLVAGPEVEEQCRQLGLPLAAPLAE 239
>gi|4557529 post-synaptic density protein 95 isoform 1 [Homo
sapiens]
Length = 767
Score = 59.7 bits (143), Expect = 2e-09
Identities = 42/119 (35%), Positives = 65/119 (54%), Gaps = 6/119 (5%)
Query: 33 APTPTSLEVSSP--PDTTEEED--HKPKLCRLAKGENGYGFHLNAIRGLPGSFIKEVQKG 88
A TPTS SP D EED +P+ + +G G GF++ G FI + G
Sbjct: 328 AMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAG 387
Query: 89 GPADLAG-LEDEDVIIEVNGVNVLDEPYEKVVDRIQSSGKNVTLLVCGK-KAYDYFQAK 145
GPADL+G L D I+ VNGV++ + +E+ ++++G+ VT++ K + Y F+AK
Sbjct: 388 GPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAK 446
>gi|192447426 post-synaptic density protein 95 isoform 2 [Homo
sapiens]
Length = 721
Score = 59.7 bits (143), Expect = 2e-09
Identities = 42/119 (35%), Positives = 65/119 (54%), Gaps = 6/119 (5%)
Query: 33 APTPTSLEVSSP--PDTTEEED--HKPKLCRLAKGENGYGFHLNAIRGLPGSFIKEVQKG 88
A TPTS SP D EED +P+ + +G G GF++ G FI + G
Sbjct: 282 AMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAG 341
Query: 89 GPADLAG-LEDEDVIIEVNGVNVLDEPYEKVVDRIQSSGKNVTLLVCGK-KAYDYFQAK 145
GPADL+G L D I+ VNGV++ + +E+ ++++G+ VT++ K + Y F+AK
Sbjct: 342 GPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAK 400
>gi|119943106 synapse-associated protein 102 isoform a [Homo
sapiens]
Length = 817
Score = 57.4 bits (137), Expect = 1e-08
Identities = 38/119 (31%), Positives = 62/119 (52%), Gaps = 4/119 (3%)
Query: 31 APAPTPTSLEVSSPPDTTEEED--HKPKLCRLAKGENGYGFHLNAIRGLPGSFIKEVQKG 88
AP P + P EED +P+ L KG G GF++ G F+ + G
Sbjct: 358 APPQVPPTRYSPIPRHMLAEEDFTREPRKIILHKGSTGLGFNIVGGEDGEGIFVSFILAG 417
Query: 89 GPADLAG-LEDEDVIIEVNGVNVLDEPYEKVVDRIQSSGKNVTLLVCGK-KAYDYFQAK 145
GPADL+G L D I+ VNGVN+ + +E+ ++ +G++VT++ + + Y F++K
Sbjct: 418 GPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQSVTIVAQYRPEEYSRFESK 476
>gi|31742501 sorting nexin family member 27 [Homo sapiens]
Length = 528
Score = 56.6 bits (135), Expect = 2e-08
Identities = 40/125 (32%), Positives = 59/125 (47%), Gaps = 30/125 (24%)
Query: 55 PKLCRLAKGENGYGFH----------LNAIRG---LPGSFIKEVQKGGPADLAGLEDEDV 101
P++ R+ K E+GYGF+ L +I G P + V GG AD AG+ D
Sbjct: 41 PRVVRIVKSESGYGFNVRGQVSEGGQLRSINGELYAPLQHVSAVLPGGAADRAGVRKGDR 100
Query: 102 IIEVNGVNVLDEPYEKVVDRIQSSGKNVTLLV-----------------CGKKAYDYFQA 144
I+EVN VNV +++VVD I++ K + L V G+ YDY +
Sbjct: 101 ILEVNHVNVEGATHKQVVDLIRAGEKELILTVLSVPPHEADNLDPSDDSLGQSFYDYTEK 160
Query: 145 KKIPI 149
+ +PI
Sbjct: 161 QAVPI 165
>gi|218156338 chapsyn-110 isoform 1 [Homo sapiens]
Length = 975
Score = 55.8 bits (133), Expect = 3e-08
Identities = 38/147 (25%), Positives = 71/147 (48%), Gaps = 4/147 (2%)
Query: 1 MSCDCQIQLAHFSPFLYYQSQELPNGSVKEAPAPTPTSLEVSSPPDTTEEEDHKPKLCRL 60
+ CD L+ +P+ +Y LP+ + + + + S + +P+ L
Sbjct: 472 VECDKSFLLS--APYSHYHLGLLPDSEMTSHSQHSTATRQPSMTLQRAVSLEGEPRKVVL 529
Query: 61 AKGENGYGFHLNAIRGLPGSFIKEVQKGGPADLAG-LEDEDVIIEVNGVNVLDEPYEKVV 119
KG G GF++ G F+ + GGPADL+G L+ D I+ VNG+++ +E+
Sbjct: 530 HKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELQRGDQILSVNGIDLRGASHEQAA 589
Query: 120 DRIQSSGKNVTLLV-CGKKAYDYFQAK 145
++ +G+ VT++ + Y F+AK
Sbjct: 590 AALKGAGQTVTIIAQYQPEDYARFEAK 616
>gi|91199538 chapsyn-110 isoform 2 [Homo sapiens]
Length = 870
Score = 55.8 bits (133), Expect = 3e-08
Identities = 38/147 (25%), Positives = 71/147 (48%), Gaps = 4/147 (2%)
Query: 1 MSCDCQIQLAHFSPFLYYQSQELPNGSVKEAPAPTPTSLEVSSPPDTTEEEDHKPKLCRL 60
+ CD L+ +P+ +Y LP+ + + + + S + +P+ L
Sbjct: 367 VECDKSFLLS--APYSHYHLGLLPDSEMTSHSQHSTATRQPSMTLQRAVSLEGEPRKVVL 424
Query: 61 AKGENGYGFHLNAIRGLPGSFIKEVQKGGPADLAG-LEDEDVIIEVNGVNVLDEPYEKVV 119
KG G GF++ G F+ + GGPADL+G L+ D I+ VNG+++ +E+
Sbjct: 425 HKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELQRGDQILSVNGIDLRGASHEQAA 484
Query: 120 DRIQSSGKNVTLLV-CGKKAYDYFQAK 145
++ +G+ VT++ + Y F+AK
Sbjct: 485 AALKGAGQTVTIIAQYQPEDYARFEAK 511
>gi|119943108 synapse-associated protein 102 isoform b [Homo
sapiens]
Length = 512
Score = 53.1 bits (126), Expect = 2e-07
Identities = 31/94 (32%), Positives = 54/94 (57%), Gaps = 2/94 (2%)
Query: 54 KPKLCRLAKGENGYGFHLNAIRGLPGSFIKEVQKGGPADLAG-LEDEDVIIEVNGVNVLD 112
+P+ L KG G GF++ G F+ + GGPADL+G L D I+ VNGVN+ +
Sbjct: 46 EPRKIILHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRN 105
Query: 113 EPYEKVVDRIQSSGKNVTLLVCGK-KAYDYFQAK 145
+E+ ++ +G++VT++ + + Y F++K
Sbjct: 106 ATHEQAAAALKRAGQSVTIVAQYRPEEYSRFESK 139
>gi|148539628 discs, large homolog 1 isoform 1 [Homo sapiens]
Length = 904
Score = 52.8 bits (125), Expect = 2e-07
Identities = 37/124 (29%), Positives = 62/124 (50%), Gaps = 2/124 (1%)
Query: 24 PNGSVKEAPAPTPTSLEVSSPPDTTEEEDHKPKLCRLAKGENGYGFHLNAIRGLPGSFIK 83
P+ + + PA VS +E +P+ L +G G GF++ G FI
Sbjct: 433 PSSFLGQTPASPARYSPVSKAVLGDDEITREPRKVVLHRGSTGLGFNIVGGEDGEGIFIS 492
Query: 84 EVQKGGPADLAG-LEDEDVIIEVNGVNVLDEPYEKVVDRIQSSGKNVTLLVCGK-KAYDY 141
+ GGPADL+G L D II VN V++ +E+ ++++G+ VT++ + + Y
Sbjct: 493 FILAGGPADLSGELRKGDRIISVNSVDLRAASHEQAAAALKNAGQAVTIVAQYRPEEYSR 552
Query: 142 FQAK 145
F+AK
Sbjct: 553 FEAK 556
>gi|148539578 discs, large homolog 1 isoform 2 [Homo sapiens]
Length = 926
Score = 52.8 bits (125), Expect = 2e-07
Identities = 37/124 (29%), Positives = 62/124 (50%), Gaps = 2/124 (1%)
Query: 24 PNGSVKEAPAPTPTSLEVSSPPDTTEEEDHKPKLCRLAKGENGYGFHLNAIRGLPGSFIK 83
P+ + + PA VS +E +P+ L +G G GF++ G FI
Sbjct: 433 PSSFLGQTPASPARYSPVSKAVLGDDEITREPRKVVLHRGSTGLGFNIVGGEDGEGIFIS 492
Query: 84 EVQKGGPADLAG-LEDEDVIIEVNGVNVLDEPYEKVVDRIQSSGKNVTLLVCGK-KAYDY 141
+ GGPADL+G L D II VN V++ +E+ ++++G+ VT++ + + Y
Sbjct: 493 FILAGGPADLSGELRKGDRIISVNSVDLRAASHEQAAAALKNAGQAVTIVAQYRPEEYSR 552
Query: 142 FQAK 145
F+AK
Sbjct: 553 FEAK 556
>gi|223278403 glutamate receptor, ionotropic, delta 2 (Grid2)
interacting protein [Homo sapiens]
Length = 1211
Score = 51.2 bits (121), Expect = 7e-07
Identities = 45/159 (28%), Positives = 70/159 (44%), Gaps = 28/159 (17%)
Query: 20 SQELPNGSVKEAPAPTPTSLEVSSPPDTTEEEDHKP---------------KLCRLAKGE 64
+Q L +E P S S+PP +E + + R+ KG
Sbjct: 227 AQRLRRSRSEERPERLLVSTRASAPPRRPDEPPPRRASLLVGGLAGPGGARRTVRVYKGN 286
Query: 65 NGYGFHLNAIRGLPGSFIKEVQKGGPADLAGLEDEDVIIEVNGVNVLDEPYEKVVDRIQS 124
+GF L RG +I+ V G PAD A L+ D I+ +NG+++ + ++KVV +Q
Sbjct: 287 KSFGFTL---RGHGPVWIESVLPGSPADNAALKSGDRILFLNGLDMRNCSHDKVVSMLQG 343
Query: 125 SGKNVTLLVCGKKAYDYFQAKKIPIVSSLADPLDTPPDS 163
SG TL+V + +P S +D LD+P S
Sbjct: 344 SGAMPTLVV---------EEGLVPFASD-SDSLDSPNPS 372
Score = 30.4 bits (67), Expect = 1.3
Identities = 20/53 (37%), Positives = 26/53 (49%), Gaps = 3/53 (5%)
Query: 67 YGFHLNAIRGLPGSFIKEVQKGGPADLAGLEDEDVIIEVNGVNVLDEPYEKVV 119
+GF L G F+ EV KG A GL D I+EV G+ V E++V
Sbjct: 17 FGFRLG---GSGPCFVLEVAKGSSAHAGGLRPGDQILEVEGLAVGGLSRERLV 66
>gi|218156340 chapsyn-110 isoform 3 [Homo sapiens]
Length = 749
Score = 51.2 bits (121), Expect = 7e-07
Identities = 30/94 (31%), Positives = 52/94 (55%), Gaps = 2/94 (2%)
Query: 54 KPKLCRLAKGENGYGFHLNAIRGLPGSFIKEVQKGGPADLAG-LEDEDVIIEVNGVNVLD 112
+P+ L KG G GF++ G F+ + GGPADL+G L+ D I+ VNG+++
Sbjct: 315 EPRKVVLHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELQRGDQILSVNGIDLRG 374
Query: 113 EPYEKVVDRIQSSGKNVTLLV-CGKKAYDYFQAK 145
+E+ ++ +G+ VT++ + Y F+AK
Sbjct: 375 ASHEQAAAALKGAGQTVTIIAQYQPEDYARFEAK 408
>gi|203097003 Rho GTPase activating protein 21 [Homo sapiens]
Length = 1958
Score = 49.3 bits (116), Expect = 3e-06
Identities = 33/95 (34%), Positives = 52/95 (54%), Gaps = 9/95 (9%)
Query: 44 PPDTTEEEDHKPKLCRLAKGENGY--GFHLNAIRGLPGSFIKEVQKGGPADLAGLEDEDV 101
PP++ + +K + ENG G N + + F+K+V++GGPA AGL D
Sbjct: 71 PPESAIQFSYKDE-------ENGNRGGKQRNRLEPMDTIFVKQVKEGGPAFEAGLCTGDR 123
Query: 102 IIEVNGVNVLDEPYEKVVDRIQSSGKNVTLLVCGK 136
II+VNG +V+ + Y +V+ IQ+S + L V K
Sbjct: 124 IIKVNGESVIGKTYSQVIALIQNSDTTLELSVMPK 158
>gi|45120119 microtubule associated serine/threonine kinase 1 [Homo
sapiens]
Length = 1570
Score = 47.4 bits (111), Expect = 1e-05
Identities = 40/123 (32%), Positives = 56/123 (45%), Gaps = 15/123 (12%)
Query: 24 PNGSVKEAPAPTPTSLEVS-SPPDTTEEEDHKPKLCRLA------KGENGYGFHLNAIRG 76
P+GS A +P SL + S D++ D+ P + L + YGF L AIR
Sbjct: 927 PHGSSPLASPMSPRSLSSNPSSRDSSPSRDYSPAVSGLRSPITIQRSGKKYGFTLRAIRV 986
Query: 77 LPGS--------FIKEVQKGGPADLAGLEDEDVIIEVNGVNVLDEPYEKVVDRIQSSGKN 128
G + V++GGPA AGL D+I VNG V + +VV+ I SG
Sbjct: 987 YMGDTDVYSVHHIVWHVEEGGPAQEAGLCAGDLITHVNGEPVHGMVHPEVVELILKSGNK 1046
Query: 129 VTL 131
V +
Sbjct: 1047 VAV 1049
>gi|148612825 Rap GTPase interactor [Homo sapiens]
Length = 1075
Score = 47.4 bits (111), Expect = 1e-05
Identities = 41/127 (32%), Positives = 55/127 (43%), Gaps = 13/127 (10%)
Query: 31 APAPTPTSLEVSSPPDTTEEEDHKPKLC-----RLAKGENGYGFHL----NAIRGLPGSF 81
AP +L SPP + C L +G +G G L + G PG +
Sbjct: 945 APEGDSAALAEESPPAPSSRSSSTEDFCYVFTVELERGPSGLGMGLIDGMHTHLGAPGLY 1004
Query: 82 IKEVQKGGPADLAG-LEDEDVIIEVNGVNVLDEPYEKVVDRIQSSGKNVTLLVCGKKAYD 140
I+ + G PA G L D I+EVNG ++L Y + VD I+ GK + LV D
Sbjct: 1005 IQTLLPGSPAAADGRLSLGDRILEVNGSSLLGLGYLRAVDLIRHGGKKMRFLVAKS---D 1061
Query: 141 YFQAKKI 147
AKKI
Sbjct: 1062 VETAKKI 1068
>gi|116875765 tight junction protein 1 isoform b [Homo sapiens]
Length = 1668
Score = 46.6 bits (109), Expect = 2e-05
Identities = 39/134 (29%), Positives = 64/134 (47%), Gaps = 18/134 (13%)
Query: 82 IKEVQKGGPADLAGLEDEDVIIEVNGVNVLDEPYEKVVDRIQSSGKNVTLLVCGKKAYDY 141
I +V KGGPA+ L++ D + VNGV++ + + V +++ SGKN + + K
Sbjct: 56 ISDVLKGGPAE-GQLQENDRVAMVNGVSMDNVEHAFAVQQLRKSGKNAKITIRRK----- 109
Query: 142 FQAKKIPIVSSLADPLDTPPDSKEGIVVESNHDSHMAK--------ERIIHSDLNASCDR 193
KK+ I S DP + D++E E HD + E+I D +AS +R
Sbjct: 110 ---KKVQIPVSRPDP-EPVSDNEEDSYDEEIHDPRSGRSGVVNRRSEKIWPRDRSASRER 165
Query: 194 IRFPNSIKNNIDGS 207
P S + ++ S
Sbjct: 166 SLSPRSDRRSVASS 179
Score = 34.7 bits (78), Expect = 0.069
Identities = 34/122 (27%), Positives = 49/122 (40%), Gaps = 16/122 (13%)
Query: 32 PAPTPTSLEVSSP-------------PDTTEEEDHKPKLCRLAKGENGYGFHLNAIRGLP 78
P P P +V P P++T E+ +L K G L G
Sbjct: 383 PEPKPVYAQVGQPDVDLPVSPSDGVLPNSTHEDGILRPSMKLVKFRKGDSVGLRLAGGND 442
Query: 79 -GSFIKEVQKGGPADLAGLEDEDVIIEVNGVNVLDEPYEKVVDRIQS--SGKNVTLLVCG 135
G F+ V + PA GLE+ D I+ VN V+ + E+ V + G+ VT+L
Sbjct: 443 VGIFVAGVLEDSPAAKEGLEEGDQILRVNNVDFTNIIREEAVLFLLDLPKGEEVTILAQK 502
Query: 136 KK 137
KK
Sbjct: 503 KK 504
>gi|116875767 tight junction protein 1 isoform a [Homo sapiens]
Length = 1748
Score = 46.6 bits (109), Expect = 2e-05
Identities = 39/134 (29%), Positives = 64/134 (47%), Gaps = 18/134 (13%)
Query: 82 IKEVQKGGPADLAGLEDEDVIIEVNGVNVLDEPYEKVVDRIQSSGKNVTLLVCGKKAYDY 141
I +V KGGPA+ L++ D + VNGV++ + + V +++ SGKN + + K
Sbjct: 56 ISDVLKGGPAE-GQLQENDRVAMVNGVSMDNVEHAFAVQQLRKSGKNAKITIRRK----- 109
Query: 142 FQAKKIPIVSSLADPLDTPPDSKEGIVVESNHDSHMAK--------ERIIHSDLNASCDR 193
KK+ I S DP + D++E E HD + E+I D +AS +R
Sbjct: 110 ---KKVQIPVSRPDP-EPVSDNEEDSYDEEIHDPRSGRSGVVNRRSEKIWPRDRSASRER 165
Query: 194 IRFPNSIKNNIDGS 207
P S + ++ S
Sbjct: 166 SLSPRSDRRSVASS 179
Score = 34.7 bits (78), Expect = 0.069
Identities = 34/122 (27%), Positives = 49/122 (40%), Gaps = 16/122 (13%)
Query: 32 PAPTPTSLEVSSP-------------PDTTEEEDHKPKLCRLAKGENGYGFHLNAIRGLP 78
P P P +V P P++T E+ +L K G L G
Sbjct: 383 PEPKPVYAQVGQPDVDLPVSPSDGVLPNSTHEDGILRPSMKLVKFRKGDSVGLRLAGGND 442
Query: 79 -GSFIKEVQKGGPADLAGLEDEDVIIEVNGVNVLDEPYEKVVDRIQS--SGKNVTLLVCG 135
G F+ V + PA GLE+ D I+ VN V+ + E+ V + G+ VT+L
Sbjct: 443 VGIFVAGVLEDSPAAKEGLEEGDQILRVNNVDFTNIIREEAVLFLLDLPKGEEVTILAQK 502
Query: 136 KK 137
KK
Sbjct: 503 KK 504
>gi|224458284 Rho GTPase activating protein 23 [Homo sapiens]
Length = 1397
Score = 44.3 bits (103), Expect = 9e-05
Identities = 21/56 (37%), Positives = 35/56 (62%)
Query: 81 FIKEVQKGGPADLAGLEDEDVIIEVNGVNVLDEPYEKVVDRIQSSGKNVTLLVCGK 136
F+K V++ GPA AGL D +++VNG +V+ + Y +V+ IQ+S + L + K
Sbjct: 5 FVKNVKEDGPAHRAGLRTGDRLVKVNGESVIGKTYSQVIALIQNSDDTLELSIMPK 60
>gi|4506509 regulator of G-protein signalling 12 isoform 2 [Homo
sapiens]
Length = 1376
Score = 44.3 bits (103), Expect = 9e-05
Identities = 33/97 (34%), Positives = 42/97 (43%), Gaps = 17/97 (17%)
Query: 26 GSVKEAPAPTPTSLEVSSPPDTTEEEDHKPKLCRLAKGENGYGFHLNAIRGLPGSFIKEV 85
G + P P P SPP E +A+G GYGF L+ G + V
Sbjct: 5 GEASKRPLPGP------SPPRVRSVE--------VARGRAGYGFTLS---GQAPCVLSCV 47
Query: 86 QKGGPADLAGLEDEDVIIEVNGVNVLDEPYEKVVDRI 122
+G PAD GL D I+ VN +NV +E VV I
Sbjct: 48 MRGSPADFVGLRAGDQILAVNEINVKKASHEDVVKLI 84
>gi|38327601 regulator of G-protein signalling 12 isoform 1 [Homo
sapiens]
Length = 1447
Score = 44.3 bits (103), Expect = 9e-05
Identities = 33/97 (34%), Positives = 42/97 (43%), Gaps = 17/97 (17%)
Query: 26 GSVKEAPAPTPTSLEVSSPPDTTEEEDHKPKLCRLAKGENGYGFHLNAIRGLPGSFIKEV 85
G + P P P SPP E +A+G GYGF L+ G + V
Sbjct: 5 GEASKRPLPGP------SPPRVRSVE--------VARGRAGYGFTLS---GQAPCVLSCV 47
Query: 86 QKGGPADLAGLEDEDVIIEVNGVNVLDEPYEKVVDRI 122
+G PAD GL D I+ VN +NV +E VV I
Sbjct: 48 MRGSPADFVGLRAGDQILAVNEINVKKASHEDVVKLI 84
>gi|47933392 cytohesin 1 interacting protein [Homo sapiens]
Length = 359
Score = 43.9 bits (102), Expect = 1e-04
Identities = 29/85 (34%), Positives = 46/85 (54%), Gaps = 9/85 (10%)
Query: 56 KLCRLAKGENG-YGFHL--------NAIRGLPGSFIKEVQKGGPADLAGLEDEDVIIEVN 106
KL + K +N +GF + NA + I ++Q+ PA AGL+ DV+ +N
Sbjct: 76 KLVTVEKQDNETFGFEIQSYRPQNQNACSSEMFTLICKIQEDSPAHCAGLQAGDVLANIN 135
Query: 107 GVNVLDEPYEKVVDRIQSSGKNVTL 131
GV+ Y++VVD I+SSG +T+
Sbjct: 136 GVSTEGFTYKQVVDLIRSSGNLLTI 160
>gi|11545920 lin-7 homolog B [Homo sapiens]
Length = 207
Score = 43.5 bits (101), Expect = 1e-04
Identities = 29/89 (32%), Positives = 48/89 (53%), Gaps = 2/89 (2%)
Query: 47 TTEEEDHKPKLCRLAKGENGYGFHLNAIRGLPGS-FIKEVQKGGPADL-AGLEDEDVIIE 104
T E P++ L K + G GF++ + +I V GG AD GL+ D ++
Sbjct: 83 TASEGHAHPRVVELPKTDEGLGFNIMGGKEQNSPIYISRVIPGGVADRHGGLKRGDQLLS 142
Query: 105 VNGVNVLDEPYEKVVDRIQSSGKNVTLLV 133
VNGV+V E +EK V+ ++++ +V L+V
Sbjct: 143 VNGVSVEGEQHEKAVELLKAAQGSVKLVV 171
>gi|18375650 protein tyrosine phosphatase, non-receptor type 13
isoform 4 [Homo sapiens]
Length = 2490
Score = 42.4 bits (98), Expect = 3e-04
Identities = 27/113 (23%), Positives = 57/113 (50%), Gaps = 2/113 (1%)
Query: 79 GSFIKEVQKGGPADLAG-LEDEDVIIEVNGVNVLDEPYEKVVDRIQSSGKNVTLLVC-GK 136
G FI V GGPADL G L+ D +I VN V++ + ++ +Q++ ++VTL++ K
Sbjct: 1120 GIFISSVAPGGPADLDGCLKPGDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQPK 1179
Query: 137 KAYDYFQAKKIPIVSSLADPLDTPPDSKEGIVVESNHDSHMAKERIIHSDLNA 189
+ + + + + + + + ++ + S+ D H ++ + H N+
Sbjct: 1180 EKISKVPSTPVHLTNEMKNYMKKSSYMQDSAIDSSSKDHHWSRGTLRHISENS 1232
Score = 35.4 bits (80), Expect = 0.040
Identities = 44/174 (25%), Positives = 71/174 (40%), Gaps = 22/174 (12%)
Query: 30 EAPAPTPTSLEVSSPPDTTEEEDHKPKLCRLAKGENGYGFHL----NAIRGLPGSFIKEV 85
+ P + +V TEE + KL K +G GF N I + I V
Sbjct: 1482 QGPEKVKKTTQVKDYSFVTEENTFEVKLF---KNSSGLGFSFSREDNLIPEQINASIVRV 1538
Query: 86 QK---GGPADLAGLEDE-DVIIEVNGVNVLDEPYEKVVDRIQSSGKNVTLLVCGKKAYDY 141
+K G PA +G D DVI++VNG ++ ++V+ ++ + V LL+C
Sbjct: 1539 KKLFPGQPAAESGKIDVGDVILKVNGASLKGLSQQEVISALRGTAPEVFLLLCRPPP--- 1595
Query: 142 FQAKKIPIVSSLADPLDTPPDSKEGIVVESNHDSHMAK--ERIIHSDLNASCDR 193
++ + L TP S ++ S+ DS E+ SD N D+
Sbjct: 1596 ------GVLPEIDTALLTPLQSPAQVLPNSSKDSSQPSCVEQSTSSDENEMSDK 1643
>gi|18375648 protein tyrosine phosphatase, non-receptor type 13
isoform 3 [Homo sapiens]
Length = 2294
Score = 42.4 bits (98), Expect = 3e-04
Identities = 27/113 (23%), Positives = 57/113 (50%), Gaps = 2/113 (1%)
Query: 79 GSFIKEVQKGGPADLAG-LEDEDVIIEVNGVNVLDEPYEKVVDRIQSSGKNVTLLVC-GK 136
G FI V GGPADL G L+ D +I VN V++ + ++ +Q++ ++VTL++ K
Sbjct: 929 GIFISSVAPGGPADLDGCLKPGDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQPK 988
Query: 137 KAYDYFQAKKIPIVSSLADPLDTPPDSKEGIVVESNHDSHMAKERIIHSDLNA 189
+ + + + + + + + ++ + S+ D H ++ + H N+
Sbjct: 989 EKISKVPSTPVHLTNEMKNYMKKSSYMQDSAIDSSSKDHHWSRGTLRHISENS 1041
Score = 35.4 bits (80), Expect = 0.040
Identities = 44/174 (25%), Positives = 71/174 (40%), Gaps = 22/174 (12%)
Query: 30 EAPAPTPTSLEVSSPPDTTEEEDHKPKLCRLAKGENGYGFHL----NAIRGLPGSFIKEV 85
+ P + +V TEE + KL K +G GF N I + I V
Sbjct: 1286 QGPEKVKKTTQVKDYSFVTEENTFEVKLF---KNSSGLGFSFSREDNLIPEQINASIVRV 1342
Query: 86 QK---GGPADLAGLEDE-DVIIEVNGVNVLDEPYEKVVDRIQSSGKNVTLLVCGKKAYDY 141
+K G PA +G D DVI++VNG ++ ++V+ ++ + V LL+C
Sbjct: 1343 KKLFPGQPAAESGKIDVGDVILKVNGASLKGLSQQEVISALRGTAPEVFLLLCRPPP--- 1399
Query: 142 FQAKKIPIVSSLADPLDTPPDSKEGIVVESNHDSHMAK--ERIIHSDLNASCDR 193
++ + L TP S ++ S+ DS E+ SD N D+
Sbjct: 1400 ------GVLPEIDTALLTPLQSPAQVLPNSSKDSSQPSCVEQSTSSDENEMSDK 1447
>gi|18375646 protein tyrosine phosphatase, non-receptor type 13
isoform 1 [Homo sapiens]
Length = 2485
Score = 42.4 bits (98), Expect = 3e-04
Identities = 27/113 (23%), Positives = 57/113 (50%), Gaps = 2/113 (1%)
Query: 79 GSFIKEVQKGGPADLAG-LEDEDVIIEVNGVNVLDEPYEKVVDRIQSSGKNVTLLVC-GK 136
G FI V GGPADL G L+ D +I VN V++ + ++ +Q++ ++VTL++ K
Sbjct: 1120 GIFISSVAPGGPADLDGCLKPGDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQPK 1179
Query: 137 KAYDYFQAKKIPIVSSLADPLDTPPDSKEGIVVESNHDSHMAKERIIHSDLNA 189
+ + + + + + + + ++ + S+ D H ++ + H N+
Sbjct: 1180 EKISKVPSTPVHLTNEMKNYMKKSSYMQDSAIDSSSKDHHWSRGTLRHISENS 1232
Score = 35.4 bits (80), Expect = 0.040
Identities = 44/174 (25%), Positives = 71/174 (40%), Gaps = 22/174 (12%)
Query: 30 EAPAPTPTSLEVSSPPDTTEEEDHKPKLCRLAKGENGYGFHL----NAIRGLPGSFIKEV 85
+ P + +V TEE + KL K +G GF N I + I V
Sbjct: 1477 QGPEKVKKTTQVKDYSFVTEENTFEVKLF---KNSSGLGFSFSREDNLIPEQINASIVRV 1533
Query: 86 QK---GGPADLAGLEDE-DVIIEVNGVNVLDEPYEKVVDRIQSSGKNVTLLVCGKKAYDY 141
+K G PA +G D DVI++VNG ++ ++V+ ++ + V LL+C
Sbjct: 1534 KKLFPGQPAAESGKIDVGDVILKVNGASLKGLSQQEVISALRGTAPEVFLLLCRPPP--- 1590
Query: 142 FQAKKIPIVSSLADPLDTPPDSKEGIVVESNHDSHMAK--ERIIHSDLNASCDR 193
++ + L TP S ++ S+ DS E+ SD N D+
Sbjct: 1591 ------GVLPEIDTALLTPLQSPAQVLPNSSKDSSQPSCVEQSTSSDENEMSDK 1638
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.135 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,111,275
Number of Sequences: 37866
Number of extensions: 494348
Number of successful extensions: 1749
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 106
Number of HSP's successfully gapped in prelim test: 53
Number of HSP's that attempted gapping in prelim test: 1500
Number of HSP's gapped (non-prelim): 281
length of query: 227
length of database: 18,247,518
effective HSP length: 99
effective length of query: 128
effective length of database: 14,498,784
effective search space: 1855844352
effective search space used: 1855844352
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.