BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|112734870 hypothetical protein LOC57648 [Homo sapiens] (1094 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 2209 0.0 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 164 6e-40 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 142 1e-33 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 140 7e-33 gi|163965366 nascent polypeptide-associated complex alpha subuni... 140 9e-33 gi|47132519 Ras association and pleckstrin homology domains 1 is... 129 1e-29 gi|160707881 formin 2 [Homo sapiens] 126 1e-28 gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 122 2e-27 gi|221139926 NHS-like 1 [Homo sapiens] 120 7e-27 gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 119 1e-26 gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 119 1e-26 gi|110349719 titin isoform N2-A [Homo sapiens] 114 5e-25 gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapi... 113 9e-25 gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 112 2e-24 gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 110 9e-24 gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 110 9e-24 gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 109 1e-23 gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 109 1e-23 gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 108 2e-23 gi|150170670 piccolo isoform 2 [Homo sapiens] 108 3e-23 gi|150378539 piccolo isoform 1 [Homo sapiens] 108 3e-23 gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens] 106 1e-22 gi|116284392 mucin 2 precursor [Homo sapiens] 105 2e-22 gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 104 5e-22 gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 104 5e-22 gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 101 4e-21 gi|55750053 atrophin-1 [Homo sapiens] 100 8e-21 gi|55750041 atrophin-1 [Homo sapiens] 100 8e-21 gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 100 8e-21 gi|153792074 proline rich 12 [Homo sapiens] 100 8e-21 >gi|112734870 hypothetical protein LOC57648 [Homo sapiens] Length = 1094 Score = 2209 bits (5723), Expect = 0.0 Identities = 1094/1094 (100%), Positives = 1094/1094 (100%) Query: 1 MAARAPPAAPAAEEPGNPGGPPRRKKSRSGASGLRRAFSWLRGKRRKKKAAGAEGAEPAA 60 MAARAPPAAPAAEEPGNPGGPPRRKKSRSGASGLRRAFSWLRGKRRKKKAAGAEGAEPAA Sbjct: 1 MAARAPPAAPAAEEPGNPGGPPRRKKSRSGASGLRRAFSWLRGKRRKKKAAGAEGAEPAA 60 Query: 61 PRAKKAEDKAKRAKGKGRGSAKAENDKHLSVGPGQGPGSAVDEHQDNVFFPSGRPPHLEE 120 PRAKKAEDKAKRAKGKGRGSAKAENDKHLSVGPGQGPGSAVDEHQDNVFFPSGRPPHLEE Sbjct: 61 PRAKKAEDKAKRAKGKGRGSAKAENDKHLSVGPGQGPGSAVDEHQDNVFFPSGRPPHLEE 120 Query: 121 LHTQAQEGLRSLQHQEKQKLNKGGWDHGDTQSIQSSRTGPDEDNISFCSQTTSYVAESST 180 LHTQAQEGLRSLQHQEKQKLNKGGWDHGDTQSIQSSRTGPDEDNISFCSQTTSYVAESST Sbjct: 121 LHTQAQEGLRSLQHQEKQKLNKGGWDHGDTQSIQSSRTGPDEDNISFCSQTTSYVAESST 180 Query: 181 AEDALSIRSEMIQRKGSTFRPHDSFPKSGKSGRRRRERRSTVLGLPQHVQKELGLRNERE 240 AEDALSIRSEMIQRKGSTFRPHDSFPKSGKSGRRRRERRSTVLGLPQHVQKELGLRNERE Sbjct: 181 AEDALSIRSEMIQRKGSTFRPHDSFPKSGKSGRRRRERRSTVLGLPQHVQKELGLRNERE 240 Query: 241 APGTPRAPGARDAVRIPTVDGRPRGTSGMGARVSLQALEAEAEAGAETEAMLQRHIDRVY 300 APGTPRAPGARDAVRIPTVDGRPRGTSGMGARVSLQALEAEAEAGAETEAMLQRHIDRVY Sbjct: 241 APGTPRAPGARDAVRIPTVDGRPRGTSGMGARVSLQALEAEAEAGAETEAMLQRHIDRVY 300 Query: 301 RDDTFVGRSTGTRAPPLTRPMSLAVPGLTGGAGPAEPLSPAMSISPQATYLSKLIPHAVL 360 RDDTFVGRSTGTRAPPLTRPMSLAVPGLTGGAGPAEPLSPAMSISPQATYLSKLIPHAVL Sbjct: 301 RDDTFVGRSTGTRAPPLTRPMSLAVPGLTGGAGPAEPLSPAMSISPQATYLSKLIPHAVL 360 Query: 361 PPTVDVVALGRCSLRTLSRCSLHSASPASVRSLGRFSSVSSPQPRSRHPSSSSDTWSHSQ 420 PPTVDVVALGRCSLRTLSRCSLHSASPASVRSLGRFSSVSSPQPRSRHPSSSSDTWSHSQ Sbjct: 361 PPTVDVVALGRCSLRTLSRCSLHSASPASVRSLGRFSSVSSPQPRSRHPSSSSDTWSHSQ 420 Query: 421 SSDTIVSDGSTLSSKGGSEGQPESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRS 480 SSDTIVSDGSTLSSKGGSEGQPESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRS Sbjct: 421 SSDTIVSDGSTLSSKGGSEGQPESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRS 480 Query: 481 SGQLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTG 540 SGQLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTG Sbjct: 481 SGQLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTG 540 Query: 541 GSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAG 600 GSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAG Sbjct: 541 GSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAG 600 Query: 601 PPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVI 660 PPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVI Sbjct: 601 PPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVI 660 Query: 661 PPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQES 720 PPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQES Sbjct: 661 PPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQES 720 Query: 721 PVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQ 780 PVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQ Sbjct: 721 PVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQ 780 Query: 781 DLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPP 840 DLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPP Sbjct: 781 DLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPP 840 Query: 841 APAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPT 900 APAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPT Sbjct: 841 APAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPT 900 Query: 901 PALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEP 960 PALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEP Sbjct: 901 PALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEP 960 Query: 961 RPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPK 1020 RPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPK Sbjct: 961 RPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPK 1020 Query: 1021 APPPVARKPSVGVPPPASPSYPRAEPLTAPPTNGLPHTQDRTKRELAENGGVLQLVGPEE 1080 APPPVARKPSVGVPPPASPSYPRAEPLTAPPTNGLPHTQDRTKRELAENGGVLQLVGPEE Sbjct: 1021 APPPVARKPSVGVPPPASPSYPRAEPLTAPPTNGLPHTQDRTKRELAENGGVLQLVGPEE 1080 Query: 1081 KMGLPGSDSQKELA 1094 KMGLPGSDSQKELA Sbjct: 1081 KMGLPGSDSQKELA 1094 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 164 bits (414), Expect = 6e-40 Identities = 285/1101 (25%), Positives = 400/1101 (36%), Gaps = 170/1101 (15%) Query: 2 AARAPPA-APAAEEPGNPGGPPRRKKSRSGASGLRRAFSWLRGKRRKKKAAGAEGAE--P 58 AAR P A AP P PG P A + A + K ++A G GA Sbjct: 13 AARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPE 72 Query: 59 AAPRA-------KKAEDKAKRAKGKGRGSAKAENDKHLSVGPGQGPGSAVDEHQDNVFFP 111 +APRA + + A R GRG +A K+ S GP PG A + Sbjct: 73 SAPRAGPTRSAGTSSRNPASRPPASGRGE-RAPPAKNTSPGPVSSPGRASGTTRPGPLGQ 131 Query: 112 SGRPPHLEELHTQAQEGLRSLQHQEKQKLNKGGWDHGDTQSIQSSRTGPDEDNISFCSQT 171 G EE + ++ + ++ L+ G DT S P + + ++ Sbjct: 132 KGLRISAEETVARG----KATEAPKRSALSAGA--RRDT-----SGPTPGTPSPAMARRS 180 Query: 172 TSYVAESSTAEDALSIR----SEMIQRKGSTFRPHDSFPKSGKSGRRRRERRSTVLGLPQ 227 + E A S R +E ++ S+ H + S + R R S GL + Sbjct: 181 RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAA----RRRPSAGGGLQR 236 Query: 228 HVQKELG---------LRNEREAPGTPRAPG--------ARDAVRIPTVDGRPRGTSGMG 270 + L R+ A GTPRAP A+R P V + + Sbjct: 237 PASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL 296 Query: 271 ARVSLQALEAEAEAGAETEAMLQRHIDRVYRDDTFVGRSTGTR--APPLTRPMSLAVPGL 328 +S L + +G + V D T +PPL P+ LA P Sbjct: 297 GPLSSSPLATPSPSGTKARP--------VPPPDNAATPLPATLPPSPPLATPLPLAPPS- 347 Query: 329 TGGAGPAEPLSPAMSISPQATYLSKLIPHAVLPPTVDVVALGRCSL----RTLSRCSLHS 384 P+ P S SP AT S+ P PP +L +L+ SL + Sbjct: 348 -----PSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQA 402 Query: 385 A-SPASVRSLGRFSSVSSPQPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPE 443 SP ++ SL +S+ SP ++ H S T S Q+ ++ S S+ S P Sbjct: 403 PPSPLALSSLQATTSLGSPTLQATH---SFLTMSPRQTQASLTSPSRPASTPPDSP--PL 457 Query: 444 SSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPPPPRR 503 + S PP Q SP+ + +++ L+ S PP Sbjct: 458 QAPLSLPASPPLQTSL---SPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLET 514 Query: 504 THSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAGA---------APCP--- 551 SL L P L PP + P L PP S APCP Sbjct: 515 QSSLAPPSLQTPPASLTTPPL---ENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQA 571 Query: 552 -PNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPP--ASPGKA 608 P+P + P + PP++P SP G P+ P LA PP A P A Sbjct: 572 PPSPLTTPPPETPSSIATPPPQAPPALASPPL-----QGLPSPPLSPLATPPPQAPPXLA 626 Query: 609 QPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPA 668 PP L++P + +S S ++ S AP+ + + P F PP P V A Sbjct: 627 LPP-------LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAP----FSPPPSPPVQA 675 Query: 669 PFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPP-----TPQTTLTPLQESPVI 723 PFSPP S P SP+ P+ A P++ P+ + P SPP TP P +P + Sbjct: 676 PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL 735 Query: 724 SKDQSPPPSPP--PSYHPP---PPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPE 778 SPP SPP PS PP PP P + V + PL P PP PPA Sbjct: 736 QVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKP--PPQAPPALA 793 Query: 779 EQDLSMADFPP---PEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQI--QPPGSP 833 L PP P +A FS ++ P P +P + P +A LQ+ PP SP Sbjct: 794 TPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVL---AAPLLQVPPSPPASP 850 Query: 834 --DPPPAPPAPAPASSAPG---HVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLL---- 884 P PP P P +S G +A P P PP + L P L Sbjct: 851 TLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP--------PPSRSPSSTLSGPDLAGHSS 902 Query: 885 ------QMVRLRSVGAPGGAPT------------PALGPSAPQKPLR-RALSGRASPVPA 925 + +R G GGA PA P PL R G P P Sbjct: 903 SATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWP- 961 Query: 926 PSSGLHAAVRLKACSLAASEGLSSAQP-NGPPEAEPRPPQSPASTASFIFSKGSRKLQLE 984 P++G +A L C++ +EG SA P G + P P S A+ + S + + Sbjct: 962 PATGPGSADGL--CTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQ 1019 Query: 985 RPVSPETQADLQRNLVAELRS 1005 + LQ ++V L S Sbjct: 1020 ARLGELPLGALQASVVQHLLS 1040 Score = 147 bits (371), Expect = 5e-35 Identities = 238/896 (26%), Positives = 319/896 (35%), Gaps = 136/896 (15%) Query: 241 APG--TPRAPGARDAVRIPTVDGRPRGTSGMGARVSLQALEAEAEAGAETEAMLQRHIDR 298 APG TPR PG+ P P +GA ++ AG A + R Sbjct: 21 APGLLTPRPPGSPR----PPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76 Query: 299 VYRDDTFVGRSTGTRAP-PLTRPMSLAVPGLTGGAGPAEPLSPAMSISPQATYLSKLIPH 357 RS GT + P +RP + +G E PA + SP Sbjct: 77 AGPT-----RSAGTSSRNPASRPPA---------SGRGERAPPAKNTSPGPVSSPGRASG 122 Query: 358 AVLPPTVDVVALGRCSLRTLSRCSLHSASPASVRSLGRFSSVSSPQPRSRHPSSSSDTWS 417 P + L + T++R A S S G S P P + P+ + Sbjct: 123 TTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMAR---- 178 Query: 418 HSQSSDTIVS---DGSTLSSKGGSEGQPES--STASNSVVPPPQGGSGRGSPSGGSTAEA 472 S+++ T V + + +EG +S S + +S P R S GG A Sbjct: 179 RSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPA 238 Query: 473 SDTLSIRSSGQLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQ-- 530 S +LS S+ LS + S + P P +GL P PP+ + Sbjct: 239 SRSLS-SSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALG 297 Query: 531 PQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGT 590 P P T G A P PP P N+ P L PP + L+P S Sbjct: 298 PLSSSPLATPSPSGTKARPVPP-PDNAATP-LPATLPPSPPLATPLPLAPPS-------- 347 Query: 591 PTLPP--KGLAGPPASPGKAQPPKP-----ERVTSLRS-PGASVSSSLTSLCSSSSDPAP 642 P+ PP + L PPA+P PP + SL++ P V SLTS S + P+P Sbjct: 348 PSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSP-SLQAPPSP 406 Query: 643 SDRSGPQILTPLGDRFVIPPH------PKVPAPFSPPPSKPRSPNPAAPALAAPAVVPG- 695 S Q T LG + H P+ PS+P S P +P L AP +P Sbjct: 407 LALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPAS 466 Query: 696 -PVSTT---DASPQSPP---------------TPQTTLTPLQESPVISKDQSPPPS--PP 734 P+ T+ SP S P +PQ L+ L P+ ++ PPS P Sbjct: 467 PPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTP 526 Query: 735 PSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNW--PPPPPPAPEEQDLSMADFPPPEE 792 P+ PP P + AP +TA PL P+ PP P P P + S PPPE Sbjct: 527 PASLTTPPLENLPSL---APPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPET 583 Query: 793 AFFSVASPEPAGPSG--------------SPELVSSPAASSSSATALQIQPPGSPDPPPA 838 S+A+P P P SP P A A PP P PP Sbjct: 584 PS-SIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPL 642 Query: 839 PPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGA 898 P P+ AP +A + P S PP + +P +P + S P A Sbjct: 643 SPLATPSPQAPNALAVHLLQAPF--SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLA 700 Query: 899 PTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLS-SAQPNGPPE 957 P P +P P +S A+P P L A S AS +S SA P PP Sbjct: 701 APPLQVPPSP--PASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATP--PPR 756 Query: 958 AEPR--------PPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQ 1009 P PP PAS +K P+ L + L S Sbjct: 757 VPPLLAAPPLQVPPSPPASLPMSPLAKPP----------PQAPPALATPPLQALPSPPAS 806 Query: 1010 RPPQAP-------KKSPKAPPPVARKPSVGVP----PPASPSYPRAEPLTAPPTNG 1054 P QAP SP A PP P + P PP+ P+ P + PPT G Sbjct: 807 FPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPG 862 Score = 138 bits (347), Expect = 3e-32 Identities = 204/759 (26%), Positives = 278/759 (36%), Gaps = 129/759 (16%) Query: 361 PPTVDVVALGRCSLRTLSRCSLHSASPASVRSLGRFSSVSSPQPRSRH-PSSSSDTWSHS 419 PP V AL R L P + R+ G + P+ R P+ S+ T S + Sbjct: 36 PPPVTPAAL-----RVLGAAGAVGRKPLAERA-GGIGGATIPESAPRAGPTRSAGTSSRN 89 Query: 420 QSSDTIVSDGSTLSSKGGSEGQPESSTASNSVVPPPQGGSG--RGSPSG--GSTAEASDT 475 +S S G E P + S V P SG R P G G A +T Sbjct: 90 PASRPPAS--------GRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEET 141 Query: 476 LS---IRSSGQLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLP-PKPERKQQP 531 ++ + + S S R+ P P + ++ +R A +GLP P P + Sbjct: 142 VARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGT-EVGLPRPAPSAR--- 197 Query: 532 QLPRPPTTGGSEGAGAAP----CPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQ 587 PRPPT G + +A P+PA P S GG + P S R+LS S+ + Sbjct: 198 --PRPPTEGPRKSVSSASEHSTTEPSPAARRRP--SAGGGLQRPAS--RSLSSSA---TP 248 Query: 588 SGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGAS-----VSSSLTSLCSSS-SDPA 641 +P G P +P PKP+ + +LR P + + +L L SS + P+ Sbjct: 249 LSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPS 308 Query: 642 PSDRSGPQILTPLGDRFVIPP-HPKVPAPFSPPPSKP-RSPNPAAPALAAPAVVPGPVST 699 PS R V PP + P P + PPS P +P P AP +P+ P + T Sbjct: 309 PSGTKA---------RPVPPPDNAATPLPATLPPSPPLATPLPLAPP--SPSAPPS-LQT 356 Query: 700 TDASPQSPPT---PQTTLTPLQESP---VISKDQSPPPSPPPSYHPPPPPTKKPEVVVEA 753 + P +PP+ P T P+Q P I Q P PS PP P + Sbjct: 357 LPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATT 416 Query: 754 PSASET--------------AEEPLQDPNWPPPPPP--APEEQDLSMADFPPPEEAFFSV 797 S T + L P+ P PP P + LS+ PP + + Sbjct: 417 SLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPA 476 Query: 798 ASPEPAGPSGSPELVSSPAASSSSATALQ--IQPPGSPDPPPAPPA--PAPASSAPGHVA 853 SP + + P S AS S L I PP APP+ PAS + Sbjct: 477 VSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLE 536 Query: 854 KLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAP-QKPL 912 LP P PP + APL TP L P AP P P +P P Sbjct: 537 NLPSLAP--------PPLQTASAPLTTPHLET--------PPCPAPCPLQAPPSPLTTPP 580 Query: 913 RRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPP-------EAEPRPPQS 965 S A+P P L A+ L+ L++ P PP +A P PP S Sbjct: 581 PETPSSIATPPPQAPPAL-ASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPAS 639 Query: 966 PA----STASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKA 1021 P +T S L+ P SP +Q PP +P SP A Sbjct: 640 PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF----------SPPASPPVSPSA 689 Query: 1022 PPPVARKPSVGVP----PPASPSYPRAEPLTAPPTNGLP 1056 PP PS+ P PP+ P+ P P PP P Sbjct: 690 TPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP 728 Score = 63.2 bits (152), Expect = 1e-09 Identities = 96/417 (23%), Positives = 136/417 (32%), Gaps = 68/417 (16%) Query: 662 PHPKVPAPFSP-PPSKPRSPNPAAPA---------------LAAPAVVPGPVSTTDASPQ 705 P + P +P PP PR P P PA LA A G + +++P+ Sbjct: 17 PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76 Query: 706 SPPTPQ---TTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEE 762 + PT ++ P P + + PP+ S P P + P + Sbjct: 77 AGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRI 136 Query: 763 PLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSA 822 ++ AP+ LS A + P P PS P + A+ + Sbjct: 137 SAEETVARGKATEAPKRSALSAG-------ARRDTSGPTPGTPS--PAMARRSRAAGTEV 187 Query: 823 TALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPS 882 + P P PP P + SSA H P GG + L + + Sbjct: 188 GLPRPAPSARPRPPTEGPRKS-VSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSA 246 Query: 883 LLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLA 942 RS + G P P+ P +P + L P P A A Sbjct: 247 TPLSSPARSGPSARGTPR---APAHPSQPKPKGLQALRPPQVTPPRKDAAP----ALGPL 299 Query: 943 ASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAE 1002 +S L++ P+G +A P PP A+T L P SP L Sbjct: 300 SSSPLATPSPSGT-KARPVPPPDNAATP----------LPATLPPSPPLATPL------- 341 Query: 1003 LRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEPLTAPPTNGLPHTQ 1059 P AP SP APP + PS PPA+P +T PP P Q Sbjct: 342 ---------PLAPP-SPSAPPSLQTLPS----PPATPPSQAPPSMTTPPMQAPPSLQ 384 Score = 62.0 bits (149), Expect = 3e-09 Identities = 109/480 (22%), Positives = 146/480 (30%), Gaps = 112/480 (23%) Query: 590 TPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSD------PAPS 643 TP GL P PG +PP P +LR GA+ + L + P + Sbjct: 16 TPAARAPGLL-TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESA 74 Query: 644 DRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNP-AAPALAAPAVVPGPVSTTDA 702 R+GP R P PP+K SP P ++P A+ PGP+ Sbjct: 75 PRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGL 134 Query: 703 SPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEE 762 + T E+P K + P P T P + + +A Sbjct: 135 RISAEET--VARGKATEAP---KRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGL 189 Query: 763 PLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAG---PSGSPELVSSPAASS 819 P P+ P PP + +S A + S P PA PS L PA+ S Sbjct: 190 PRPAPSARPRPPTEGPRKSVSSA-------SEHSTTEPSPAARRRPSAGGGL-QRPASRS 241 Query: 820 SSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLV 879 S++A P +PA S P G PR Sbjct: 242 LSSSAT--------------PLSSPARSGPS---------------ARGTPRAPAHPSQP 272 Query: 880 TPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSG-RASPVPAPSSGLHAAVRLKA 938 P LQ +R V P PALGP + + SG +A PVP P + Sbjct: 273 KPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDN---------- 322 Query: 939 CSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRN 998 A+ L + P PP A P P P+ Sbjct: 323 ----AATPLPATLPPSPPLATPLPLAPPS------------------------------- 347 Query: 999 LVAELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEPLTAPPTNGLPHT 1058 P AP P P A PS P +P L P +PH+ Sbjct: 348 -------------PSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHS 394 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 142 bits (359), Expect = 1e-33 Identities = 195/733 (26%), Positives = 277/733 (37%), Gaps = 97/733 (13%) Query: 313 RAPPLTRPMSLAVPGLTGGAGPAEPLSPAMSISPQATYLSKLIPHAVLPPTVDVVALGRC 372 R PP P +L V G G G +PL+ AT + + P A T A GR Sbjct: 34 RPPPPVTPAALRVLGAAGAVG-RKPLAERAGGIGGAT-IPESAPRAGPTRTSRPPASGRG 91 Query: 373 SLRTLSRCSLHSASPASVRSLGRFSSVSSPQPRSRHPS--SSSDTWSHSQSSD----TIV 426 ++ + SP V S GR S + P P + S+ +T + ++++ + + Sbjct: 92 ERAPPAK----NTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSAL 147 Query: 427 SDGSTLSSKGGSEGQPESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTL-SIRSSGQLS 485 S G+ + G + G P + A S + G R +PS S+ S+ + S Sbjct: 148 SAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHS 207 Query: 486 GRSVSLRKLKRPPP------PPRRTHSLHQRGLAVP--DGPL--GLPPKPERKQQP---- 531 S +RP P R+ S L+ P GP G P P QP Sbjct: 208 TTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKG 267 Query: 532 -QLPRPP--TTGGSEGAGA-APCPPNPANSWVPGLSPGGSRRPPRS--PERTLSPSSGYS 585 Q RPP T + A A P +P + P P S P P +P S + Sbjct: 268 LQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQAT 327 Query: 586 SQSGTPTLPPKG--LAGPPASPGKAQPPKPERVTSL---RSPGASVSSSLTSLCSSSSDP 640 + G+PTL L PP SP PP+ +L ++P + +S S ++ S Sbjct: 328 TSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQ 387 Query: 641 APSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTT 700 AP+ + + P F PP P V APFSPP S P SP+ P+ A P++ P+ Sbjct: 388 APNALAVHLLQAP----FSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP 443 Query: 701 DASPQSPPTPQTTLTPLQESPVISKD----QSPPPSPPPSYHPPP------PPTKKPEVV 750 + P SPP + P Q P ++ PPP PP+ PP PP P Sbjct: 444 PSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQA 503 Query: 751 VEAPSA----SETAEEPLQDP--------NWPPPPPPAPEEQDLSMADFPPPEEAF---- 794 +PSA S A P Q P PP PP +P Q P P+ + Sbjct: 504 PFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPR 563 Query: 795 --FSVASPEPAGPSGSP-ELVSSP--AASSSSATALQIQPPG---------SPDPPP--- 837 ++A P PS SP +S P A SSSAT+ + G + PPP Sbjct: 564 LTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAE 623 Query: 838 -----------APPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQM 886 P P APG P G + G E G TP+ + Sbjct: 624 LAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGAL 683 Query: 887 VRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEG 946 S G GG G A + ++A G P+ A + + + + LAA+EG Sbjct: 684 DPGPSPGTSGGKAAAGAGAGASSRSPKQARLGEL-PLGALQASVVQHLLSRTLLLAAAEG 742 Query: 947 LSSAQPNGPPEAE 959 + GP AE Sbjct: 743 AAGGSGGGPGGAE 755 Score = 123 bits (308), Expect = 1e-27 Identities = 187/683 (27%), Positives = 249/683 (36%), Gaps = 167/683 (24%) Query: 386 SPASVRSLGRFSSVSSPQPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPESS 445 +PA++R LG +V R T S G T +S+ + G+ E + Sbjct: 40 TPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRA-----GPTRTSRPPASGRGERA 94 Query: 446 TASNSVVPPPQGGSGRGS------PSG--GSTAEASDTLS---IRSSGQLSGRSVSLRKL 494 + + P P GR S P G G A +T++ + + S S R+ Sbjct: 95 PPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRD 154 Query: 495 KRPPPPPRRTHSLHQRGLAVPDGPLGLP-PKPERKQQPQLPRPPTTGGSEGAGAAP---- 549 P P + ++ +R A +GLP P P + PRPPT G + +A Sbjct: 155 TSGPTPGTPSPAMARRSRAAGT-EVGLPRPAPSAR-----PRPPTEGPRKSVSSASEHST 208 Query: 550 CPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQ 609 P+PA P S GG + P S R+LS S+ + +P G P +P Sbjct: 209 TEPSPAARRRP--SAGGGLQRPAS--RSLSSSA---TPLSSPARSGPSARGTPRAPAHPS 261 Query: 610 PPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAP 669 PKP+ + +LR P + D AP+ L PL + P P P Sbjct: 262 QPKPKGLQALRPP---------QVTPPRKDAAPA-------LGPLSSSPLATPSPSAPPS 305 Query: 670 FSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPT----PQTTLTPLQESPVISK 725 S PPS P+P PA P +T+ SP T P L+PL P Sbjct: 306 PSAPPSLQTLPSP-------PATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPP---- 354 Query: 726 DQSPPP-SPPPSYHPPPPPTKKPEVVVEAPSA---SETAEEPLQDPNWPPPPPPAPEEQD 781 Q+PP + PP PP PP P + PS + A LQ P PPP PP Sbjct: 355 PQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPV----- 409 Query: 782 LSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQI------QPPGSPDP 835 A F PP ASP P PS +P S A S +A LQ+ PP SP Sbjct: 410 --QAPFSPP-------ASP-PVSPSATPP---SQAPPSLAAPPLQVPPSPPASPPMSPSA 456 Query: 836 PPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAP 895 P P AP P ++ P +AK P + PP L TP L Q + P Sbjct: 457 TPPPQAPPPLAAPPLQLAKPPPQ---------APPA------LATPPL-QALPSPPASFP 500 Query: 896 GGAPTPALGPSA--PQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPN 953 G AP PSA P PL A+P P L A + Sbjct: 501 GQAP---FSPSASLPMSPL-------ATPPPQAPPVLAAPLL------------------ 532 Query: 954 GPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQ 1013 + P PP SP A RP +P S+S R Sbjct: 533 ---QVPPSPPASPTLQAP------------RRPPTPGPDT-----------SVSGPRLTL 566 Query: 1014 APKKSPKAPPPVARKPSVGVPPP 1036 A +P PPP +R PS + P Sbjct: 567 A--LAPGPPPPPSRSPSSTLSGP 587 Score = 92.8 bits (229), Expect = 2e-18 Identities = 128/513 (24%), Positives = 172/513 (33%), Gaps = 110/513 (21%) Query: 590 TPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSD------PAPS 643 TP GL P PG +PP P +LR GA+ + L + P + Sbjct: 16 TPAARAPGLL-TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESA 74 Query: 644 DRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNP-AAPALAAPAVVPGPVS---- 698 R+GP R PP PP+K SP P ++P A+ PGP+ Sbjct: 75 PRAGPT-------RTSRPPASGRGE--RAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGL 125 Query: 699 ------------TTDASPQSP-----------PTPQTTLTPLQESPVISKDQSPPPSPPP 735 T+A +S PTP T + + + P P P Sbjct: 126 RISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAP 185 Query: 736 SYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFF 795 S P PP T+ P V + S T E P PA + + P Sbjct: 186 SARPRPP-TEGPRKSVSSASEHSTTE-----------PSPAARRRPSAGGGLQRPASRSL 233 Query: 796 S-----VASPEPAGPS--GSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSA 848 S ++SP +GPS G+P + P+ P +P A PA P SS+ Sbjct: 234 SSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS 293 Query: 849 PGHVAKLPQKEPVGCSKGGGPPR-EDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSA 907 P L P PP + + +P TP S+G+P T + PS Sbjct: 294 P-----LATPSPSAPPSPSAPPSLQTLPSPPATPPSQATT---SLGSPTLQATHSFLPSP 345 Query: 908 PQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPA 967 P PL A+P P A L+ PP PP SP Sbjct: 346 PLSPL-------ATPPPQ-----------------APPALALPPLQAPPSPPASPPLSPL 381 Query: 968 STASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVAR 1027 +T S L+ P SP +Q PP +P SP A PP Sbjct: 382 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF----------SPPASPPVSPSATPPSQA 431 Query: 1028 KPSVGVP----PPASPSYPRAEPLTAPPTNGLP 1056 PS+ P PP+ P+ P P PP P Sbjct: 432 PPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP 464 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 140 bits (353), Expect = 7e-33 Identities = 193/722 (26%), Positives = 268/722 (37%), Gaps = 100/722 (13%) Query: 311 GTRAPPL--TRPMSLAVPGLTGGAGPAEPLSP-AMSISPQATYLSKLIPHAVLPPTVDVV 367 G RAPP T P ++ PG G PL + IS + T A P + Sbjct: 100 GERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEA---PKRSAL 156 Query: 368 ALGRCSLRTLSRCSLHSASPASVR---SLGRFSSVSSPQPRSR-HPSSSSDTWSHSQSSD 423 + G + R S + + SPA R + G + P P +R P + S S +S+ Sbjct: 157 SAG--ARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 214 Query: 424 TIVSDGSTLS----SKGGSEGQPESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIR 479 ++ S + S GG +P S + S+S P R PS T A S Sbjct: 215 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP--LSSPARSGPSARGTPRAPAHPS-- 270 Query: 480 SSGQLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQ---PQLPRP 536 + L+ L+ P P R + G + PL P Q P LP Sbjct: 271 -----QPKPKGLQALRPPQVTPPRKDAAPALG-PLSSSPLATPSPSAALQSQAPPTLPAT 324 Query: 537 PTTGGSEGAGAAPCP-PNPANSWVPGLS--PGGSRRPPRSPERTLSPSSGYSSQSGTPTL 593 P + A P P P+ S P L P PP +L + ++ S P+ Sbjct: 325 PHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSP 384 Query: 594 PPKGLAGPP--ASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQIL 651 P LA PP A P A PP L++P + +S S ++ S AP+ + + Sbjct: 385 PLSPLATPPPQAPPALALPP-------LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ 437 Query: 652 TPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQ 711 P F PP P V APFSPP S P SP+ P+ A P++ P+ + P SPP Sbjct: 438 AP----FSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP 493 Query: 712 TTLTPLQESPVISKD----QSPPPSPPPSYHPPP------PPTKKPEVVVEAPSA----S 757 + P Q P ++ PPP PP+ PP PP P +PSA S Sbjct: 494 SATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMS 553 Query: 758 ETAEEPLQDP--------NWPPPPPPAPEEQDLSMADFPPPEEAF------FSVASPEPA 803 A P Q P PP PP +P Q P P+ + ++A P Sbjct: 554 PLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 613 Query: 804 GPSGSP-ELVSSP--AASSSSATALQIQPPG---------SPDPPP-------------- 837 PS SP +S P A SSSAT+ + G + PPP Sbjct: 614 PPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSR 673 Query: 838 APPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGG 897 P P APG P G + G E G TP+ + S G GG Sbjct: 674 GPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGG 733 Query: 898 APTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPE 957 G A + ++A G P+ A + + + + LAA+EG + GP Sbjct: 734 KAAAGAGAGASSRSPKQARLGEL-PLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGG 792 Query: 958 AE 959 AE Sbjct: 793 AE 794 Score = 128 bits (322), Expect = 3e-29 Identities = 179/684 (26%), Positives = 249/684 (36%), Gaps = 128/684 (18%) Query: 429 GSTLSSKGGSEGQPESSTAS--NSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSG---- 482 G+T+ G S+ S N PP G G +P +T+ + R+SG Sbjct: 67 GATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP 126 Query: 483 -------------------------QLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDG 517 + S S R+ P P + ++ +R A Sbjct: 127 GPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAA-GT 185 Query: 518 PLGLP-PKPERKQQPQLPRPPTTGGSEGAGAA----PCPPNPANSWVPGLSPGGSRRPPR 572 +GLP P P + PRPPT G + +A P+PA P S GG + P Sbjct: 186 EVGLPRPAPSAR-----PRPPTEGPRKSVSSASEHSTTEPSPAARRRP--SAGGGLQRPA 238 Query: 573 SPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTS 632 S R+LS S ++ +P G P +P PKP+ + +LR P Sbjct: 239 S--RSLSSS---ATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPP---------Q 284 Query: 633 LCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPA--LAAP 690 + D AP+ L PL + P P PP+ P +P+ ++ LA P Sbjct: 285 VTPPRKDAAPA-------LGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATP 337 Query: 691 AVVPGPVSTTDAS----PQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKK 746 + P + S P P TP + T SP + S PSPP S PPP Sbjct: 338 LPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAP 397 Query: 747 PEVV---VEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPE----EAFFSVAS 799 P + ++AP S A PL P P P L A F PP +A FS + Sbjct: 398 PALALPPLQAP-PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA 456 Query: 800 PEPAGPSGSPELVSSPAASSSSATALQI------QPPGSPDPPPAPPAPAPASSAPGHVA 853 P PS +P S A S +A LQ+ PP SP P P AP P ++ P +A Sbjct: 457 SPPVSPSATP---PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLA 513 Query: 854 KLPQKEPVGCSKG-----GGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPA-----L 903 K P + P + PP G +PS + + P P A + Sbjct: 514 KPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQV 573 Query: 904 GPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPP 963 PS P P +A R P P P + + + L+ A GPP P P Sbjct: 574 PPSPPASPTLQA--PRRPPTPGPDTSV------------SGPRLTLALAPGPP---PPPS 616 Query: 964 QSPASTASFIFSKGSRKLQLERP-------VSPETQADLQRNLVAELRSISEQRPPQAPK 1016 +SP+ST S G P PE A AEL + P A Sbjct: 617 RSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACH----PAAWS 672 Query: 1017 KSPKAPPPVARKPSVGVPPPASPS 1040 + P PP+A + + G P P P+ Sbjct: 673 RGP--APPLAFRGAPGAPLPWPPA 694 Score = 98.2 bits (243), Expect = 4e-20 Identities = 125/517 (24%), Positives = 173/517 (33%), Gaps = 79/517 (15%) Query: 590 TPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSD------PAPS 643 TP GL P PG +PP P +LR GA+ + L + P + Sbjct: 16 TPAARAPGLL-TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESA 74 Query: 644 DRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNP-AAPALAAPAVVPGPVS---- 698 R+GP R P PP+K SP P ++P A+ PGP+ Sbjct: 75 PRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGL 134 Query: 699 ------------TTDASPQSP-----------PTPQTTLTPLQESPVISKDQSPPPSPPP 735 T+A +S PTP T + + + P P P Sbjct: 135 RISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAP 194 Query: 736 SYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFF 795 S P PP T+ P V + S T E P PA + + P Sbjct: 195 SARPRPP-TEGPRKSVSSASEHSTTE-----------PSPAARRRPSAGGGLQRPASRSL 242 Query: 796 S-----VASPEPAGPS--GSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSA 848 S ++SP +GPS G+P + P+ P +P A PA P SS+ Sbjct: 243 SSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS 302 Query: 849 PGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALG--PS 906 P L P + PP P + Q+ + P + P+L PS Sbjct: 303 P-----LATPSPSAALQSQAPPTLPA-TPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPS 356 Query: 907 APQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLA---ASEGLSSAQPNGPPEAEPRPP 963 P P +A + SP + + L + A L+ PP PP Sbjct: 357 PPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPP 416 Query: 964 QSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPP 1023 SP +T S L+ P SP +Q PP +P SP A P Sbjct: 417 LSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF----------SPPASPPVSPSATP 466 Query: 1024 PVARKPSVGVP----PPASPSYPRAEPLTAPPTNGLP 1056 P PS+ P PP+ P+ P P PP P Sbjct: 467 PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP 503 Score = 94.4 bits (233), Expect = 5e-19 Identities = 165/638 (25%), Positives = 220/638 (34%), Gaps = 139/638 (21%) Query: 472 ASDTLSIRSSGQLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQ-- 529 A+ T + R+ G L+ R + PPPP +L G A G +G P ER Sbjct: 13 AARTPAARAPGLLTPRPPGSPR----PPPPVTPAALRVLGAA---GAVGRKPLAERAGGI 65 Query: 530 -----QPQLPR--PPTTGGSEGAGAAPCPPN--------PANSWVPG--LSPG---GSRR 569 PR P + G+ A PP PA + PG SPG G+ R Sbjct: 66 GGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTR 125 Query: 570 PPRSPERTLSPSSGYSSQSGTPTLPPKGLA---GPPASPGKAQPPKPERVTSLRSPGASV 626 P ++ L S+ + G T PK A G P P + RS A Sbjct: 126 PGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGT 185 Query: 627 SSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPN----- 681 L PAPS R P P H P P+ R P+ Sbjct: 186 EVGLPR-------PAPSARPRPPTEGPRKSVSSASEHSTT----EPSPAARRRPSAGGGL 234 Query: 682 --PAAPALAAPAVVPGPVSTTDAS-PQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYH 738 PA+ +L++ A P+S+ S P + TP+ P Q P + PP PP Sbjct: 235 QRPASRSLSSSAT---PLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKD 291 Query: 739 PPPP--PTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFS 796 P P + +PSA+ ++ P P P P L+ P Sbjct: 292 AAPALGPLSSSPLATPSPSAALQSQAP-------PTLPATPHSSSLTCQLATP-----LP 339 Query: 797 VASPEPAGPSGSPELVSSPAASSSSATA------LQIQPPGSPDPPPAPPAPAPASSAPG 850 +A P P+ P L S PA S AT LQ P PP +P A P AP Sbjct: 340 LAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLA-TPPPQAPP 398 Query: 851 HVAKLPQKEPVGCSKGGGPPREDVGAPLVTPS--LLQMVRLRSVGAPGGAPTPALGPSAP 908 +A P + P PP +PL TPS + + + AP P P Sbjct: 399 ALALPPLQAPPS------PPASPPLSPLATPSPQAPNALAVHLLQAPFSPP--------P 444 Query: 909 QKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPAS 968 P++ S ASP +PS+ + A L++ PP PP SP++ Sbjct: 445 SPPVQAPFSPPASPPVSPSATPPSQ---------APPSLAAPPLQVPPSPPASPPMSPSA 495 Query: 969 TASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARK 1028 T P +P A P Q K P+APP +A Sbjct: 496 TPP--------------PQAPPPLA---------------APPLQLAKPPPQAPPALATP 526 Query: 1029 PSVGVP-PPAS-----PSYPRA----EPLTAPPTNGLP 1056 P +P PPAS P P A PL PP P Sbjct: 527 PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPP 564 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 140 bits (352), Expect = 9e-33 Identities = 201/809 (24%), Positives = 284/809 (35%), Gaps = 131/809 (16%) Query: 315 PPLTRPMSLAVPGLTGGAGPAEPLS-PAMSISPQAT-----------YLSKLIPHAVLP- 361 P P + P T P P S P+ S+ P T + S L P A P Sbjct: 709 PVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPK 768 Query: 362 --PTVDVVALGRCSLRTLSRCSLHSASPASVRSLGRFSSVSSPQPRSRHPSSSSDTWSHS 419 PT D A S + S SP LG S + +P ++ S+ DT + Sbjct: 769 ECPTEDSGASATASSKGTLTYLADSPSP-----LGVSVSPQTKRPPTKKGSAGPDTPIGN 823 Query: 420 QSSDTIVSDGSTLSSKGGS-EGQPESSTASNSVVPPPQGGSGRGSPSGGSTAEASD---T 475 SS + S L S +G +S ++S PP S +G+P+ + S T Sbjct: 824 LSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPP----SPKGAPTPSAVTPLSPKGVT 879 Query: 476 LSIRSSGQLSGRSVSLRKLKRPPPPPRR------THSLHQRGLAVPDGPLGLPPKPERKQ 529 L + + S ++ K P P++ T S ++ A P P G+P P K Sbjct: 880 LPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATP-APKGIPASPSPKG 938 Query: 530 QPQLPR--PPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQ 587 P P PP+ G P P+ W P P + P+ T SP + Sbjct: 939 APTPPAATPPSPKGG--------PATPSPKWAP-TPPAATPPSPKGGPATPSPKGAPTPP 989 Query: 588 SGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSG 647 + TP P G PA+P P P VT G+ ++ S+ P G Sbjct: 990 AATPPSPK----GGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKG 1045 Query: 648 PQILTPLGDRFVIPPHPKVPAPFSPP--PSKPRSPNPAA---------PALAAPAVVPGP 696 TPL P +P+P P PS +P P A PA +P P P Sbjct: 1046 SPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMP 1105 Query: 697 VSTTDASPQ----SPPTPQTTLTPLQESPVISKD-QSPPPSPPPSYHPPPPPTKKPEVVV 751 + T SP+ +PP TP P +PPP P+ PP+ K + Sbjct: 1106 PAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLAT 1165 Query: 752 EAPSASETAEEPLQDPNWPPPPP------PAPEEQDLSMADFPPPEEAFFSVASPE--PA 803 P + T P PP P P+P+ + A PP + + SP+ P Sbjct: 1166 PPPKGAPTT------PAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPT 1219 Query: 804 GPSGSPE------LVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQ 857 P+ +P SP + ++ A P G P PP AP P ++ P + Sbjct: 1220 TPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSL----- 1274 Query: 858 KEPVGCSKGGGPPREDVGAP---LVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRR 914 KGG GAP +VTP +P G P + AP P Sbjct: 1275 -------KGGLATPPHKGAPNPAVVTPP-----------SPKGGPATSPPKGAPTPPAAT 1316 Query: 915 ALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPN---GPPEAEPRP-PQSPASTA 970 S + SP P G + S + L + P+ GP + P PA+T Sbjct: 1317 PPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATP 1376 Query: 971 SFIFSKGSRKLQLER-PVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAP--PPVAR 1027 S +R P P + D V P +PKK+P P A Sbjct: 1377 SHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVI----------PLSPKKAPATPVTREGAA 1426 Query: 1028 KPSVG--VPPPASPSYPRAEPLTAPPTNG 1054 PS G PP +P + P T+ P G Sbjct: 1427 TPSKGDLTPPAVTPVSLKKAPATSAPKGG 1455 Score = 136 bits (342), Expect = 1e-31 Identities = 184/722 (25%), Positives = 250/722 (34%), Gaps = 80/722 (11%) Query: 386 SPASVRSLGRFSSVSSPQPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPE-- 443 SP + F +S P + PS + + +TL S G P Sbjct: 1018 SPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLK 1077 Query: 444 -SSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPPPPR 502 + T + P P+GG SP G A+ S + ++ K P P Sbjct: 1078 GAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGG-------LATPPHKGAPTTPA 1130 Query: 503 RTHSLHQRGLAVPDGPLGLPPKPER---KQQPQLPRPPTTGGSEGAGAAPCPPN-----P 554 T + GLA P P G P P + L PP G A P P P Sbjct: 1131 ATPPSPKGGLATPP-PKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATP 1189 Query: 555 ANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGP-----PASPGKAQ 609 + P +P + P+ T SP ++ + TP P GLA P P +P A Sbjct: 1190 SPKGAP-TTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA-AT 1247 Query: 610 PPKPERVTSLRSP-GASVSSSLT--SLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKV 666 PP P+ + P GA + T SL + P P ++TP + P Sbjct: 1248 PPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPK 1307 Query: 667 PAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVI--S 724 AP +PP + P SP +P P P P + T SP+ PT T + P S Sbjct: 1308 GAP-TPPAATPPSPK-GSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSS 1365 Query: 725 KDQSPPPSPPPSYHPPP---PPTKKPEVVVEAPSASETAEE--PLQDPNWPPPPPPAPEE 779 K+ PP+ PS+ P PP+ K + +P T+ PL P P Sbjct: 1366 KEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGA 1425 Query: 780 QDLSMADFPPPEEAFFSVA-SPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPA 838 S D PP S+ +P + P G P SS T + PP SP PPA Sbjct: 1426 ATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSS----KGDPTLPAVTPP-SPKEPPA 1480 Query: 839 P--------PAPAPASSAPGHVAKLPQKEPVGCSKGGGPP--REDVGAPLVT-------- 880 P P APA+ AP LP P + P R D AP T Sbjct: 1481 PKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPA 1540 Query: 881 ---PSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLK 937 P + +V +P P AP P + S + P+ G + L Sbjct: 1541 TLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELL 1600 Query: 938 ACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQR 997 S A P P P P + PA+ A KG+ PV+P + D Sbjct: 1601 IPPAVTSPSPKEA-PTPPAVTPPSPEKGPATPAP----KGT---PTSPPVTPSSLKDSPT 1652 Query: 998 NLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEPLTAPPTNGLPH 1057 + A + PQA K P P A K + P P S P+ PT P Sbjct: 1653 S-PASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPES------TPIITAPTRKGPQ 1705 Query: 1058 TQ 1059 T+ Sbjct: 1706 TK 1707 Score = 130 bits (327), Expect = 7e-30 Identities = 208/833 (24%), Positives = 297/833 (35%), Gaps = 129/833 (15%) Query: 311 GTRAPPLTRPMSLAVPGLTGGAGPAE--PLSP-AMSISPQATYLSKLI--------PHAV 359 G++ P T S P G P+ PLSP +++ P+ T ++ P Sbjct: 845 GSKDSPATTH-SPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATP 903 Query: 360 LPPTVDVVALGRCSLRTLSRCSLHSASPASVRSLGRFSSVSSPQPRSRH-PSSSSDTWSH 418 P +++ S + PAS G + ++ P + P++ S W+ Sbjct: 904 APKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAP 963 Query: 419 SQSSDTIVSDGSTLSSKGG-SEGQPESSTASNSVVPP-PQGGSGRGSPSGGSTAEASDTL 476 + + T S KGG + P+ + + PP P+GG SP G T A Sbjct: 964 TPPAAT------PPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPP 1017 Query: 477 SIRSSGQLSG--RSVSLRKLKRPPPP----------------PRRTHSLHQRGLAVPD-- 516 S + S + + S PP P P T + G A P Sbjct: 1018 SPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLK 1077 Query: 517 ----GPLGLPPKPERKQQPQLPR----PPTTGGSEGAGAAPCPPNPANSWVPGLSP---- 564 P PP P+ P+ PP G PP+ P +P Sbjct: 1078 GAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPK 1137 Query: 565 GGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGL-----AGPPASPGKAQPPKPERVTSL 619 GG PP T ++ S + G T PPKG A PP+ G P P+ + Sbjct: 1138 GGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPT- 1196 Query: 620 RSPGASVSSSLTSLCSSSSDPAP--------SDRSGPQILTPLG---DRFVIPPHPKVPA 668 +P A+ S L + S AP S + G +P G PP PK Sbjct: 1197 -TPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPK-GG 1254 Query: 669 PFSPPPSKPRSPNPAAP-----ALAAPAV--VPGPVSTTDASPQSPPT---PQTTLTPLQ 718 P +PPP +P A P LA P P P T SP+ P P+ TP Sbjct: 1255 PATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPA 1314 Query: 719 ESPVISKDQ--SPPP--SPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPP 774 +P K +PPP +P P PP P P + PS+ P P PP Sbjct: 1315 ATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTP-SSKEGPTPPA 1373 Query: 775 PAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPD 834 P + P P+ A P P G SP ++ S A A + G+ Sbjct: 1374 ATPSHKGGPAMTPPSPKRG---PAIPSPKGDPTSPAVIP---LSPKKAPATPVTREGAAT 1427 Query: 835 PPPA---PPAPAPASSAPGHVAKLPQKEPVGCSKGGGP--PREDVGAPLVTPSLLQMVRL 889 P PPA P S P+ P S G P P +P P+ Q+ Sbjct: 1428 PSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATS 1487 Query: 890 RS------VGAPGGAPT-PALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLA 942 S AP GAPT PA+ PS+P K + S R P+ AP++ L + + +LA Sbjct: 1488 SSPKKAPATPAPMGAPTLPAVIPSSP-KEVPATPSSRRDPI-APTATLLS--KKTPATLA 1543 Query: 943 ASEGL-----SSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQ--ADL 995 E L + P P A P P ++PA+ +S ++ V+P T A Sbjct: 1544 PKEALIPPAMTVPSPKKTP-AIPTPKEAPATPSS-------KEASSPPAVTPSTYKGAPS 1595 Query: 996 QRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEPLT 1048 + L+ I +PK++P P P G PA P + P+T Sbjct: 1596 PKELL-----IPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVT 1643 Score = 128 bits (322), Expect = 3e-29 Identities = 216/945 (22%), Positives = 322/945 (34%), Gaps = 138/945 (14%) Query: 160 PDEDNISFCSQTTSYVAESSTAEDALSIRSEMIQRKGSTFRPHDSFPKSGKSGRRRRERR 219 PD +++ + +S + + T +D ++ + + +G+ F P ++G + ++ Sbjct: 510 PDPEDLK--NLPSSVLVKFPTQKDLQTVPASL---EGAPFSP----AQAGLTTKKDPTVL 560 Query: 220 STVLGLPQHVQKELGLRNEREAPGTPRAPGARDAVRIPTVDGRPRG--TSGMGARVSLQA 277 V P++ + E P +P A A+ ++ P G+P TS +G S Sbjct: 561 PLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASV 620 Query: 278 LEAEAEAGAETEAMLQRH---------IDRVYRDDTFVGRSTGTRAPPLTRPMSLAVPGL 328 ++ ++ AG ++ L + D V +T T S + G Sbjct: 621 IKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGT 680 Query: 329 TGGAGPAEPLSPA-MSISPQATYLSKLIPHAVLP-----PTVDVVALGRCSLRTLSRCSL 382 A P+ ++ P S+ P A P P +V S Sbjct: 681 VSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLP 740 Query: 383 HSASPASVRSLGRFSSVSSPQPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQP 442 + +P + + S S+ P + SS + + + S TL+ S Sbjct: 741 PAGTPPGTKKVDGISHTSALAPVA---SSPKECPTEDSGASATASSKGTLTYLADSPSPL 797 Query: 443 ESSTASNSVVPPPQGGS-GRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPPPP 501 S + + PP + GS G +P G ++ S + L S+S + K P Sbjct: 798 GVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPV----EASFLPENSLSFQGSKDSPATT 853 Query: 502 RRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTG---GSEGAGAAPCPPNPANSW 558 +G P L PK + P P EG P PA Sbjct: 854 HSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEG------PATPAPKQ 907 Query: 559 VPGLSPGGSRRPPRSPERTLSPSSGYSSQS--GTPTLP---PKGLAGPPASPGKAQPPKP 613 P LS S P+ T +P +S S G PT P P G PA+P P P Sbjct: 908 APALSMTSSS--PKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTP 965 Query: 614 ERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLG---DRFVIPPHPK---VP 667 T G + S + + PS + GP +P G V PP PK Sbjct: 966 PAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAA 1025 Query: 668 APF-----SPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQS-PPTPQTTLTPLQESP 721 PF +PP + P SP + A P P + T SP+ P TP P + Sbjct: 1026 TPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAA 1085 Query: 722 VISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQD 781 + P +P P P PP P +P P P PP+P+ Sbjct: 1086 TPPSPKGGPATPSPKGAPMPPAATPP-----SPKGGLATPPHKGAPTTPAATPPSPKGGL 1140 Query: 782 LSMADFPPPEEAFFSVAS--PEPAGPSGSPELVSSPAASSSSATALQIQPPG---SPDPP 836 + PPP+ A + A+ P P G +P P + ++ A P G +P P Sbjct: 1141 AT----PPPKGAPTTPAATPPSPKGGLATPP----PKGAPTTPAATPPSPKGGLATPSPK 1192 Query: 837 PAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPG 896 AP PA +P P + + PP G L TPS P Sbjct: 1193 GAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGG--LATPS------------PK 1238 Query: 897 GAPT-PALGPSAPQKPLRRALSGRASPVP--APSSGLHAAVRLKACSLAASEGLSSAQPN 953 GAPT PA P +P+ G A+P P AP+ LK GL++ Sbjct: 1239 GAPTTPAATPPSPK-------GGPATPPPKGAPTPPAATPPSLKG-------GLATPPHK 1284 Query: 954 GPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQ 1013 G P P SP + KG+ P P P Sbjct: 1285 GAPNPAVVTPPSPKGGPATSPPKGA-------PTPPAAT-------------------PP 1318 Query: 1014 APKKSPKAPPPVARKPSVGVPPPASPSYPRAEPLTAPPTNGLPHT 1058 +PK SP PPP V PP+ P P T P + G P T Sbjct: 1319 SPKGSPGTPPPKGAPTPPAVTPPSPKGTPTL-PATTPSSKGGPTT 1362 Score = 124 bits (312), Expect = 4e-28 Identities = 211/860 (24%), Positives = 297/860 (34%), Gaps = 175/860 (20%) Query: 315 PPLTRPMSLAVPGLTGGAGPAEPLSPAMSISPQATYLSK---LIPHAVLPPTVDVVALGR 371 PP + A P G + P P+ SP AT L K P A LP G Sbjct: 1016 PPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKG----GP 1071 Query: 372 CSLRTLSRCSLHSASPASVRS-LGRFSSVSSPQPRSRHPSSSSDTWSHSQSSDTIVSDGS 430 + + +A+P S + S +P P + P S + + + Sbjct: 1072 ATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAA 1131 Query: 431 TLSS-KGG-SEGQPESSTASNSVVPP-PQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGR 487 T S KGG + P+ + + + PP P+GG P G T A+ S + Sbjct: 1132 TPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGG------ 1185 Query: 488 SVSLRKLKRPPPPPRRTHSLHQRGLAVPDG------PLGLPPKPERKQQPQLPR-PPTTG 540 ++ K P P T + GLA P P PP P+ P+ PTT Sbjct: 1186 -LATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1244 Query: 541 GS-----EGAGAAPCP---PNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPT 592 + +G A P P P P + P L GG PP + + S + G T Sbjct: 1245 AATPPSPKGGPATPPPKGAPTPPAATPPSLK-GGLATPPHKGAPNPAVVTPPSPKGGPAT 1303 Query: 593 LPPKGLAGPPA--------SPGKAQP---PKPERVTSLRSPGASVSSSLTSLCSSSSDPA 641 PPKG PPA SPG P P P VT SP + + T+ S Sbjct: 1304 SPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTP-PSPKGTPTLPATTPSSKGGPTT 1362 Query: 642 PSDRSGPQ--ILTPL--GDRFVIPPHPK----VPAPFSPPPSK---PRSPN--PAAPALA 688 PS + GP TP G + PP PK +P+P P S P SP PA P Sbjct: 1363 PSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTR 1422 Query: 689 APAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSP------------PPS 736 A P S D +P P T L+++P S + P +P PPS Sbjct: 1423 EGAATP---SKGDLTP-----PAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPS 1474 Query: 737 YHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMAD---------- 786 P PP K +P + P+ P P P +P+E + + Sbjct: 1475 --PKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTAT 1532 Query: 787 -------------------------------FPPPEEAFFSVASPEPAGP--------SG 807 P P+EA + +S E + P G Sbjct: 1533 LLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKG 1592 Query: 808 SP---ELVSSPAASSSSATALQIQP---PGSPDPPPAPPAPAPASSAPGHVAKLPQKEP- 860 +P EL+ PA +S S P P SP+ PA PAP ++P + P Sbjct: 1593 APSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPT 1652 Query: 861 ----VGCSKGGGPPREDVGAPLVT-PSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRA 915 V C G P+ G P P+ L+ V + AP TP + + P + Sbjct: 1653 SPASVTCKMGATVPQASKGLPAKKGPTALKEVLV----APAPESTPIITAPTRKGPQTKK 1708 Query: 916 LSGRASPV-PAPSSGLHAAVRLKACSLA--------ASEGLSSAQPNGPPEAEPRPPQSP 966 S + P+ P PS+ + L + A +S+ + P+ PP+S Sbjct: 1709 SSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESK 1768 Query: 967 ASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVA 1026 AST P T A ++ ++ + S S P P P AP PV Sbjct: 1769 AST-------------------PLTAAAFEK-VLPKPESASVSAAPSPPVSLPLAPSPVP 1808 Query: 1027 RKPSVGVPPPASPSYPRAEP 1046 P P+SP P Sbjct: 1809 TLPPKQQFLPSSPGLVLESP 1828 Score = 105 bits (262), Expect = 2e-22 Identities = 161/666 (24%), Positives = 220/666 (33%), Gaps = 121/666 (18%) Query: 433 SSKGGSEGQPESSTASNSVVPPP--QGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVS 490 S KGG P + +VV PP +GG P G T A+ S + S Sbjct: 1273 SLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGT------ 1326 Query: 491 LRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPR--PPTTGG----SEG 544 PPP+ P P PP P K P LP P + GG S Sbjct: 1327 --------PPPK----------GAPTPPAVTPPSP--KGTPTLPATTPSSKGGPTTPSSK 1366 Query: 545 AGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPAS 604 G P P++ P ++P +R P P SP +S + P P K A P Sbjct: 1367 EGPTPPAATPSHKGGPAMTPPSPKRGPAIP----SPKGDPTSPAVIPLSPKKAPATPVTR 1422 Query: 605 PGKAQPPK----PERVTSL---RSPGASVSSSLTSLCSSSSDPA------PSDRSGP--- 648 G A P K P VT + ++P S + SS DP PS + P Sbjct: 1423 EGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPK 1482 Query: 649 QILTPLGDRFVIPPHPKVPAPF----------SPPPSKPRSPNPAAPALAAPAVVPGPVS 698 Q+ T + P PAP S P P +P+ +A A + + Sbjct: 1483 QVATSSSPKKA----PATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKT 1538 Query: 699 TTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASE 758 +P+ P P + P+ P S PP P APS E Sbjct: 1539 PATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKE 1598 Query: 759 -------TAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPEL 811 T+ P + P P PP+PE+ A+P P G SP + Sbjct: 1599 LLIPPAVTSPSPKEAPTPPAVTPPSPEK----------------GPATPAPKGTPTSPPV 1642 Query: 812 VSSPAASSSSATALQIQPPGSPDPPPAPPAPA---PASSAPGHVAKLPQKEPV---GCSK 865 S S ++ A G+ P + PA P + VA P+ P+ K Sbjct: 1643 TPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRK 1702 Query: 866 GGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAP-QKPLRRALSGR----- 919 G + +P + P G+ G T A P P QK + G+ Sbjct: 1703 GPQTKKSSATSPPICPD-----PSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHS 1757 Query: 920 -----ASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIF 974 A P S+ L AA K S +S+A P+ P P P F Sbjct: 1758 PKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAA-PSPPVSLPLAPSPVPTLPPKQQF 1816 Query: 975 SKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQ--APKKSPKAPPPVARKPSVG 1032 S L LE P P AD EL + P P +S P + + Sbjct: 1817 LPSSPGLVLESPSKPLAPADED-----ELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIP 1871 Query: 1033 VPPPAS 1038 VP P++ Sbjct: 1872 VPTPSA 1877 Score = 89.0 bits (219), Expect = 2e-17 Identities = 179/793 (22%), Positives = 272/793 (34%), Gaps = 112/793 (14%) Query: 309 STGTRAPPLTRPM--SLAVPGLTGGAGPAEPLSPAMSISPQATYLSKLIPHAVLPPTVDV 366 S G+ PL + S+ + G TG + ++P +S+ +T S +V+PP Sbjct: 304 SLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPS- 362 Query: 367 VALGRCSLRTLSRCSLHSASPASVRSLGRFSSVSSPQPRSRHPSSSSDTWSHSQSSDTIV 426 R + + + +P+ + SS++ S + ++S +S S ++ I+ Sbjct: 363 ----RNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATS---FSLSPTTSLIL 415 Query: 427 SDGSTLSSKGGSEGQPESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSI-RSSGQLS 485 + Q S+ + + + +P+ +T E + +S SSG +S Sbjct: 416 KSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPT--TTFEVATCVSPPMSSGPIS 473 Query: 486 G-RSVSLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQ--LPRPPTT--- 539 S L P P+ + L +P P LP + K P L + PT Sbjct: 474 NIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSP-PLPDPEDLKNLPSSVLVKFPTQKDL 532 Query: 540 ----GGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPP 595 EGA +P P + P P SP + SS S TL Sbjct: 533 QTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAK 592 Query: 596 KGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGP----QIL 651 K L G P GK +S+ SP SS+ S + P D +GP ++ Sbjct: 593 KSL-GEPLPIGKP-------ASSMTSPLGVNSSASVIKTDSYAGP---DSAGPLLKSSLI 641 Query: 652 TPLGDRFVIPPHPKVPAPFSPPPSKPRSP--NPAAPALAAPAVVPGPVSTTDASPQSPPT 709 TP F P PA +P +K S A+P L T +P++ P Sbjct: 642 TPTVAAF--PLESADPAGVAPTTAKGTSTYTTTASPFLEG---------TVSLAPKNHPV 690 Query: 710 PQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNW 769 + TLT L P S++ PSP + P PE+ PS P P Sbjct: 691 KEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPS-------PSLPPAG 743 Query: 770 PPP--------------------PPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSP 809 PP P P E + A + SP P G S SP Sbjct: 744 TPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSP 803 Query: 810 ELVSSPAASSSSATALQIQPPGSPDPP----PAPPAPAPASSAPGHVAKLPQKEPVGCSK 865 + P S+ PD P +P +P AS P + + + Sbjct: 804 QTKRPPTKKGSA----------GPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATT 853 Query: 866 GGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPA 925 P GAP TPS + + + V P P PS P + +P A Sbjct: 854 HSPTPPSPKGAP--TPSAVTPLSPKGVTLP---PKETPTPSVVNLPFPKEGPATPAPKQA 908 Query: 926 PSSGLHAAVRLKACSLAASEGL-SSAQPNG---PPEAEPRPPQSPASTASFIFSKGSRKL 981 P+ + ++ KA + A +G+ +S P G PP A P P+ +T S ++ Sbjct: 909 PALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWA------ 962 Query: 982 QLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSY 1041 P P + A PP A SPK P PP +P Sbjct: 963 ----PTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPS 1018 Query: 1042 PRAEPLTAPPTNG 1054 P+ P P G Sbjct: 1019 PKGSPAATPFPKG 1031 Score = 55.5 bits (132), Expect = 3e-07 Identities = 115/506 (22%), Positives = 169/506 (33%), Gaps = 97/506 (19%) Query: 316 PLTRPMSLAVPGLTGGAGPAEPLSPAMSISPQATYLSKLIP------HAVLPPTVDVVAL 369 P+ P AV + PA P S I+P AT LSK P A++PP + V Sbjct: 1499 PMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVP-- 1556 Query: 370 GRCSLRTLSRCSLHSASPASVRSLGRFSSVSSPQPRSRHPSSSSDTWSHSQSSDTIVSDG 429 S + +PA+ S SSP P+ + T+ + S ++ Sbjct: 1557 ---SPKKTPAIPTPKEAPATPSS----KEASSP------PAVTPSTYKGAPSPKELLIPP 1603 Query: 430 STLSSKGGSEGQPESSTASNSVVPP-PQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRS 488 + S P+ + +V PP P+ G +P G T+ S++ S Sbjct: 1604 AVTSPS------PKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDS------- 1650 Query: 489 VSLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPK------------PERKQQPQLPRP 536 P P T + G VP GLP K P + P + P Sbjct: 1651 --------PTSPASVTCKM---GATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAP 1699 Query: 537 PTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPK 596 G +A PP + S G +P + S +++ + PK Sbjct: 1700 TRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPK 1759 Query: 597 GLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGD 656 G PP S KA P A+ L S+S APS P + PL Sbjct: 1760 GPLAPPES--KASTPLT---------AAAFEKVLPKPESASVSAAPS----PPVSLPLA- 1803 Query: 657 RFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTP 716 P P VP + PP + P+ L +P+ P + P PP P + P Sbjct: 1804 -----PSP-VP---TLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVP 1854 Query: 717 LQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPA 776 Q V P+P + P P P+ K V + ++ P Sbjct: 1855 FQSVLV------NMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDS--------DESVPE 1900 Query: 777 PEEQDLSMADFPPPEEAFFSVASPEP 802 EEQD + A + A + EP Sbjct: 1901 LEEQDSTQATTQQAQLAAAAEIDEEP 1926 Score = 48.9 bits (115), Expect = 3e-05 Identities = 137/607 (22%), Positives = 196/607 (32%), Gaps = 135/607 (22%) Query: 531 PQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGT 590 P LP P + + CP + AN P SP P S SSG + GT Sbjct: 43 PTLPPPCSPAPQQ------CPLSAANQASPFPSPSTIASTPLEVPFPQS-SSGTALPLGT 95 Query: 591 ----PTLPPKGLAGPPASPGKAQPPKPERVTSLR-SPGASVSSSLTSLC-----SSSSDP 640 PT P L GPP SP P +L+ +P +S +L +L SS+ P Sbjct: 96 APEAPTFLPN-LIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFP 154 Query: 641 APSDRSGPQILTPLGDRFVI------PPHPK-----VPAPFSPPPSKPRSP--------- 680 S P + + P PK VP+ P P SP Sbjct: 155 PNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPY 214 Query: 681 ---NPAAP-----------------ALAAPAVVPGPVSTTDASPQSPPT---------PQ 711 P A A+A+P V +S+ SPQ+P + P Sbjct: 215 HCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPA 274 Query: 712 TTLTPLQESPVISKDQ-SPPPSPPPSY-----------------------HPPPPPTKKP 747 Q PV++ Q + P+ PP + P P Sbjct: 275 ALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDP 334 Query: 748 EV-VVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPE-PAGP 805 V + +S A P Q PP P S + P A F V +P GP Sbjct: 335 TVKTISVDHSSTGASYPSQRSVIPPLP---------SRNEVVPATVAAFPVVAPSVDKGP 385 Query: 806 SGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPA----PAPASSAPGHVAKLPQKEPV 861 S + SP+ S + AT+ + P S +P A P A V P Sbjct: 386 STISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTN 445 Query: 862 GCSKGGGPPREDVGAPLVTPSL----LQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALS 917 C+ P A V+P + + + S A AP PS R Sbjct: 446 PCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPV 505 Query: 918 GRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGP-------------PEAEPRPPQ 964 P P L ++V +K + + + ++ P P P Sbjct: 506 SPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQA 565 Query: 965 SPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPP 1024 +P ++ SF + S ++ P+SPE A L + +S+ E P P S +P Sbjct: 566 APKNSPSFQSTSSSPEI----PLSPE--ATLAK------KSLGEPLPIGKPASSMTSPLG 613 Query: 1025 VARKPSV 1031 V SV Sbjct: 614 VNSSASV 620 Score = 48.1 bits (113), Expect = 4e-05 Identities = 69/301 (22%), Positives = 101/301 (33%), Gaps = 23/301 (7%) Query: 734 PPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEA 793 P + P P + V+ + + S TA P PPP PAP++ LS A+ P Sbjct: 10 PATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASP--- 66 Query: 794 FFSVASPEPAGPSGSPELVSSPAASSSSATALQIQP------PGSPDPPPAPPAPAPASS 847 P P+ + +P V P +SS +A L P P PP +P A A AS Sbjct: 67 -----FPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASP 121 Query: 848 APGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPT--PALGP 905 K + P + P+LL +V G T + P Sbjct: 122 MIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAP 181 Query: 906 SAPQKPLRRALS-------GRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEA 958 S P+ L + S G SP S+ + V A + L P Sbjct: 182 SEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAI 241 Query: 959 EPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKS 1018 + ++ I + L L+ PVSP L + + S + P P Sbjct: 242 ASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDF 301 Query: 1019 P 1019 P Sbjct: 302 P 302 Score = 47.4 bits (111), Expect = 8e-05 Identities = 90/401 (22%), Positives = 134/401 (33%), Gaps = 67/401 (16%) Query: 680 PNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHP 739 P P P +PA P+S + + P TPL+ + QS + P Sbjct: 41 PGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLE----VPFPQSSSGTALPLGTA 96 Query: 740 PPPPTKKPEVVVEAPSASETA-EEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFS-- 796 P PT P ++ S + A P+ P P + +++A + + F Sbjct: 97 PEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPN 156 Query: 797 -VASPE--PAGPSGSPELVSSPAASSSSATALQIQPPG-SPDPPPAPPAPAPASSAPGH- 851 + SP SGS +S+P A S T L P P+P P P S+ P H Sbjct: 157 LLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHC 216 Query: 852 ----------VAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTP 901 VA LPQ P + +P V + + V + Sbjct: 217 VTPMASIQSGVASLPQTTPTTTLA--------IASPQVKDTTISSVLI------------ 256 Query: 902 ALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPR 961 +PQ P +L G SP AA+ L SL ++S+Q P P Sbjct: 257 -----SPQNPGSLSLKGPVSP--------PAALSLSTQSLPV---VTSSQKTAGPNTPPD 300 Query: 962 PPQSPASTASFIFSKGSRKLQLERPVSPETQAD-LQRNLVAELRSISEQRP------PQA 1014 P S S + + +QL P +D + + + S P P Sbjct: 301 FPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPL 360 Query: 1015 PKKSPKAPPPVARKPSVGVPPPASPSYPRAEPLTAPPTNGL 1055 P ++ P VA P V PS +T P+ L Sbjct: 361 PSRNEVVPATVAAFPVVAPSVDKGPS--TISSITCSPSGSL 399 Score = 34.7 bits (78), Expect = 0.51 Identities = 62/287 (21%), Positives = 95/287 (33%), Gaps = 46/287 (16%) Query: 308 RSTGTRAPPLTRPMSLAVP----GLTGGAGPAEPLSPAMSISPQATYLSKLIPHAVLPPT 363 + + T +T M VP GL GP ++ +P++T + + PT Sbjct: 1648 KDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPI-------ITAPT 1700 Query: 364 VDVVALGRCSLRTLSRCSLHSASPASVRSLGRFSSVSSPQPRSRHPSSSSDTWSHSQSSD 423 + S + C SA S L S +P P SS T ++ D Sbjct: 1701 RKGPQTKKSSATSPPICPDPSAKNGSKGPL----STVAPAPLLPVQKDSSKT---AKGKD 1753 Query: 424 TIVSDGSTLSSKGGSEGQPESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQ 483 S L+ P ++ A V+P P+ S +PS Sbjct: 1754 ASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSP----------------- 1796 Query: 484 LSGRSVSLRKLKRPPP--PPRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGG 541 VSL P P PP++ GL + L P E + P +P P +GG Sbjct: 1797 ----PVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGG 1852 Query: 542 SEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQS 588 P P ++ +P +P + P + SG S S Sbjct: 1853 VPFQSVLVNMPTPKSAGIPVPTPSA-----KQPVTKNNKGSGTESDS 1894 Score = 32.3 bits (72), Expect = 2.5 Identities = 33/132 (25%), Positives = 45/132 (34%), Gaps = 18/132 (13%) Query: 926 PSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLER 985 P AV + +L+ + L P PP P P Q P S A+ Q Sbjct: 17 PQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAAN----------QASP 66 Query: 986 PVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPS-YPRA 1044 SP T A + S P ++P P + + PP SP+ A Sbjct: 67 FPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNL-------IGPPISPAALALA 119 Query: 1045 EPLTAPPTNGLP 1056 P+ AP G P Sbjct: 120 SPMIAPTLKGTP 131 >gi|47132519 Ras association and pleckstrin homology domains 1 isoform 1 [Homo sapiens] Length = 1250 Score = 129 bits (325), Expect = 1e-29 Identities = 172/695 (24%), Positives = 249/695 (35%), Gaps = 116/695 (16%) Query: 410 SSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPESSTASNSVVPPPQGGSGRGSPSGGST 469 SSS + S S S S+ S S G S+ QP S S+V + + G+ Sbjct: 531 SSSIKSGSSSSSIPESQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKR----GTQ 586 Query: 470 AEASDTLSIRSSGQLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQ 529 E S + S ++ SL P P ++ Q +P P PP P Sbjct: 587 LEESSKARMES---MNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPP---PPPPPPPP 640 Query: 530 QPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLS-----PGGSRRPPRSPERTLSPSSGY 584 P P PP S + + P S + L G +PP P Sbjct: 641 PPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVM-------- 692 Query: 585 SSQSGTPTL--PPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSS----- 637 SQS P + PP G+ PP P PP P +PG++++ + C+ S Sbjct: 693 QSQSVKPQILVPPNGVVPPPPPP----PPPP-------TPGSAMAQLKPAPCAPSLPQFS 741 Query: 638 SDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPV 697 + P P Q +T + PP P +PAP PP P P +P P Sbjct: 742 APPPPLKIHQVQHITQVAPP-TPPPPPPIPAPL--PPQAPPKPL---------VTIPAPT 789 Query: 698 STTDASP----QSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEA 753 ST +P +PPTP + P ++ P PP P P PPP K + Sbjct: 790 STKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAK 849 Query: 754 PSASETAEEP-----LQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGS 808 P S + P + PPP PPA E Q L ++ +V + PS Sbjct: 850 PPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSI 909 Query: 809 PELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAP-GHVAKLPQKEPVGCSKGG 867 P V SP + + PP P P PAPP P P +++P + P K+ S G Sbjct: 910 P--VPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPG 967 Query: 868 G---PPREDVGAPLVT-----------PSLLQMVRLRSVGAPGGAPTPAL--GPSAPQKP 911 G PP + + + PS+ +V + A G+P+ P+AP KP Sbjct: 968 GKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKP 1027 Query: 912 LRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTAS 971 + LSG V P V KA L+ S + PP PP P Sbjct: 1028 GKLNLSG----VNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPP----- 1078 Query: 972 FIFSKGSRKLQLERPVSP-ETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPP------ 1024 + E P+ P E A N ++ ++ Q + KAPPP Sbjct: 1079 ----------ETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRN 1128 Query: 1025 ---------VARKPSVGVPPPASPSYPRAEPLTAP 1050 ++ +P++ P P+ P++ P Sbjct: 1129 DSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQP 1163 Score = 93.2 bits (230), Expect = 1e-18 Identities = 117/457 (25%), Positives = 164/457 (35%), Gaps = 94/457 (20%) Query: 617 TSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSK 676 TSL S SS +S+ S S+ + SG P G + V + FS + Sbjct: 527 TSLSSSSIKSGSSSSSIPESQSNHSNQSDSGVSDTQPAGH---VRSQSIVSSVFSEAWKR 583 Query: 677 PRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPS 736 ++ A P SPQ P T T Q SP + PPP PPP Sbjct: 584 GTQLEESSKARMESMNRPYTSLVPPLSPQ--PKIVTPYTASQPSPPLPP---PPPPPPP- 637 Query: 737 YHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFS 796 PPPPP PPPPPP P + S P + + Sbjct: 638 --PPPPP--------------------------PPPPPPLPSQSAPSAGSAAPMFVKYST 669 Query: 797 VASPEPAGP-SGSPELVSSPAASSSSATALQIQPPGS---PDPPPAPPAPAPASSAPGHV 852 + + A SG+ +P S + QI P + P PPP PP P P S+ Sbjct: 670 ITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSA----- 724 Query: 853 AKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPA----LGPSAP 908 + Q +P C+ P AP + Q+ + V P P P L P AP Sbjct: 725 --MAQLKPAPCA----PSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAP 778 Query: 909 QKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPAS 968 KPL +PAP+S + + ++ A P P P + PA Sbjct: 779 PKPL--------VTIPAPTS-----------TKTVAPVVTQAAPPTPTPPVPPAKKQPAF 819 Query: 969 TASFIFSKGSRKLQLERPVSPETQ-ADLQRNLVAELRSISEQRPPQAPKKSPKAP-PPVA 1026 AS+I P SP T + + + +S + PP SP +P P V Sbjct: 820 PASYI------------PPSPPTPPVPVPPPTLPKQQSFCAKPPP-----SPLSPVPSVV 862 Query: 1027 RKPSVGVPPPASPSYPRAEPLTAPPTNGLPHTQDRTK 1063 ++ + PPP +P ++PL P N P + K Sbjct: 863 KQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVK 899 Score = 30.8 bits (68), Expect = 7.3 Identities = 17/59 (28%), Positives = 27/59 (45%) Query: 3 ARAPPAAPAAEEPGNPGGPPRRKKSRSGASGLRRAFSWLRGKRRKKKAAGAEGAEPAAP 61 A PP P A + G P +K S++ + G ++ + K ++GAE EP P Sbjct: 937 APPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRP 995 >gi|160707881 formin 2 [Homo sapiens] Length = 1722 Score = 126 bits (317), Expect = 1e-28 Identities = 156/567 (27%), Positives = 189/567 (33%), Gaps = 98/567 (17%) Query: 446 TASNSVVPPPQG---GSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPPPPR 502 T S S PPP +G+G P S +S + + PPP P Sbjct: 804 TQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPC 863 Query: 503 RTHSLHQRGLA-VPDGPLGLPPKP-ERKQQPQLPRPPTTGGSE----------GAGAAPC 550 S GL VP P LP +P+PP G+E GAG P Sbjct: 864 TESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPP 923 Query: 551 PPNPANSWVP--GLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKA 608 PP P +P L G PP P + P P LP G+ PP PG Sbjct: 924 PPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPP---------PPLPGAGIPLPPPLPGAG 974 Query: 609 QPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPA 668 PP P PGA + + P P +G PL + PP P A Sbjct: 975 IPPPPPL------PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA 1028 Query: 669 PFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQS 728 PPP P + P P L + P P P PP P + P P+ Sbjct: 1029 GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP--PPPLPGAGIP 1086 Query: 729 PPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFP 788 PPP P + PPPPP P V + P PL PPPPP L A P Sbjct: 1087 PPPPLPGAGIPPPPPL--PGVGIPPPP-------PLPGAGIPPPPP-------LPGAGIP 1130 Query: 789 PPEEAFFSVASPEPAGPS-GSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASS 847 PP + P P P G P P A L PG+ PPP PP P Sbjct: 1131 PPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPL----PGAGIPPP-PPLPGVGIP 1185 Query: 848 APGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALG-PS 906 P PP VG P P L G P P P +G P Sbjct: 1186 PP-------------------PPLPGVGIPPPPP-------LPGAGIPPPPPLPGMGIPP 1219 Query: 907 APQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSP 966 AP A P+P P +G+ L + S+ P PP P Sbjct: 1220 AP-----------APPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLP 1268 Query: 967 ASTASFIFS--KGSRKLQLE--RPVSP 989 + + KGSRK +E RP+ P Sbjct: 1269 SGLFGLGMNQDKGSRKQPIEPCRPMKP 1295 Score = 125 bits (315), Expect = 2e-28 Identities = 157/567 (27%), Positives = 190/567 (33%), Gaps = 96/567 (16%) Query: 323 LAVPGLTGGAGPAEPLSPAMSISPQATYLSKLIPHAVLPPTVDVVALGRCSLRTLSRCSL 382 L +P + G G P P PQ + S++ +V+ R S++ S Sbjct: 755 LTLPPVDGLPG-RPPCPPGAESGPQTKFCSEISL---------IVSPRRISVQLDSHQPT 804 Query: 383 HSAS-PASVRSLGRFSSVSSPQPRSRHPSSSSDTW--SHSQSSDTIVSDGSTLSSKGGSE 439 S S P SL S QP S+ P S S + SH S + + + S Sbjct: 805 QSISQPPPPPSL--LWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLP 862 Query: 440 GQPESSTASN-SVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPP 498 SS+ +VPPP P G T + +I L G + PP Sbjct: 863 CTESSSSMPGLGMVPPPP------PPLPGMTVPTLPSTAIPQPPPLQGTEML------PP 910 Query: 499 PPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSW 558 PPP P G+PP P LP PP G AG P PP P + Sbjct: 911 PPP-------------PLPGAGIPPPPPLPGAGILPLPPLPG----AGIPPPPPLPGAAI 953 Query: 559 VPG--LSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERV 616 P L G PP P + P P LP G+ PP PG PP P Sbjct: 954 PPPPPLPGAGIPLPPPLPGAGIPPP---------PPLPGAGIPPPPPLPGAGIPPPPPL- 1003 Query: 617 TSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSK 676 PGA + + P P +G PL + PP P A PPP Sbjct: 1004 -----PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1058 Query: 677 PRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPS 736 P + P P L + P P P PP P + P P + PPP P P Sbjct: 1059 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVG---IPPPPPLPG 1115 Query: 737 YHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPP----PAPEEQDLSMADFPPPEE 792 PPPP P A PL PPPPP P L A PPP Sbjct: 1116 AGIPPPPP--------LPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPP 1167 Query: 793 AFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPP----GSPDPPPAP-----PAPA 843 + P P P V P + PP G P PPP P PAPA Sbjct: 1168 LPGAGIPPPPPLPG-----VGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPA 1222 Query: 844 PASSAPGHVAKLPQKEPVGCSKGGGPP 870 P PG P PV GPP Sbjct: 1223 PPLPPPGTGIPPPPLLPV-----SGPP 1244 Score = 106 bits (265), Expect = 1e-22 Identities = 159/620 (25%), Positives = 194/620 (31%), Gaps = 158/620 (25%) Query: 452 VPPPQGGSGR-----GSPSGGSTAEASDTLSIRSSGQLSGRSVS---LRKLKRPPPPPRR 503 +PP G GR G+ SG T S+ I S ++S + S + + +PPPPP Sbjct: 757 LPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSL 816 Query: 504 THSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLS 563 S Q P PP + + + + P PP + Sbjct: 817 LWSAGQ------GQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSM 870 Query: 564 PGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQ-PPKPERVTSLRSP 622 PG PP P P G + PTLP + PP G PP P + P Sbjct: 871 PGLGMVPPPPP-----PLPGMT----VPTLPSTAIPQPPPLQGTEMLPPPPPPL-----P 916 Query: 623 GASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNP 682 GA + P P +G L PL + PP P A PPP P + P Sbjct: 917 GAGIPP-----------PPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIP 965 Query: 683 AAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPP 742 P L + P P P PP P + P P+ PPP P + PPPP Sbjct: 966 LPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP--PPPLPGAGIPPPPPLPGAGIPPPP 1023 Query: 743 PTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEP 802 P P A PL PPPPP L A PPP P Sbjct: 1024 PL---------PGAGIPPPPPLPGAGIPPPPP-------LPGAGIPPPP----------P 1057 Query: 803 AGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSA-PGHVAKLPQKEPV 861 +G P P A G P PPP P A P PG A +P P+ Sbjct: 1058 LPGAGIPPPPPLPGA-------------GIPPPPPLPGAGIPPPPPLPG--AGIPPPPPL 1102 Query: 862 -GCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRA 920 G PP G P P L G P P P G P PL R G Sbjct: 1103 PGVGIPPPPPLPGAGIPPPPP-------LPGAGIPPPPPLPGAG-IPPPPPLPRV--GIP 1152 Query: 921 SPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRK 980 P P P +G+ P PP P + Sbjct: 1153 PPPPLPGAGI-----------------------------PPPPPLPGAGIP--------- 1174 Query: 981 LQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPAS-P 1039 P P L + PP P PPP+ P G+PPP P Sbjct: 1175 -----PPPP-------------LPGVGIPPPPPLPGVGIPPPPPL---PGAGIPPPPPLP 1213 Query: 1040 SY---PRAEPLTAPPTNGLP 1056 P P PP G+P Sbjct: 1214 GMGIPPAPAPPLPPPGTGIP 1233 Score = 97.1 bits (240), Expect = 8e-20 Identities = 120/432 (27%), Positives = 144/432 (33%), Gaps = 76/432 (17%) Query: 431 TLSSKGGSEGQPESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSG-----QLS 485 TL S + P T PPP G+G P A + +G L Sbjct: 890 TLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLP 949 Query: 486 GRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDGPL---GLPPKPERKQQPQLPRPPTTGGS 542 G ++ PPPPP L G+ +P PL G+PP P P PP G Sbjct: 950 GAAI-------PPPPP-----LPGAGIPLPP-PLPGAGIPPPPPLPGAGIPPPPPLPGAG 996 Query: 543 -------EGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPP 595 GAG P PP P P G+ PP P P +G P LP Sbjct: 997 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP----LPGAGIPPP---PPLPG 1049 Query: 596 KGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLG 655 G+ PP PG PP P PGA + + P P +G PL Sbjct: 1050 AGIPPPPPLPGAGIPPPPPL------PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1103 Query: 656 DRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLT 715 + PP P A PPP P + P P L + P P P PP P + Sbjct: 1104 GVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIP 1163 Query: 716 P--------LQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDP 767 P + P + PPP P P PPPP P A PL P Sbjct: 1164 PPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPP--------PLPGAGIPPPPPL--P 1213 Query: 768 NWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQI 827 PP PAP PPP P P P P L+ P SS+ Q+ Sbjct: 1214 GMGIPPAPAP--------PLPPPGTGI----PPPPLLPVSGPPLL--PQVGSSTLPTPQV 1259 Query: 828 QPPGSPDPPPAP 839 PPP P Sbjct: 1260 ---CGFLPPPLP 1268 Score = 93.2 bits (230), Expect = 1e-18 Identities = 100/354 (28%), Positives = 120/354 (33%), Gaps = 42/354 (11%) Query: 440 GQPESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVS----LRKLK 495 G P + +PPP G G P A I L G + L Sbjct: 941 GIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAG----IPPPPPLPGAGIPPPPPLPGAG 996 Query: 496 RPPPPPRRTHSLHQRGLAVPDGP----LGLPPKPERKQQPQLPRPPTTGGS-------EG 544 PPPPP G +P P G+PP P P PP G G Sbjct: 997 IPPPPPLP-------GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1049 Query: 545 AGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPAS 604 AG P PP P P G+ PP P P +G P LP G+ PP Sbjct: 1050 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPP----LPGAGIPPP---PPLPGAGIPPPPPL 1102 Query: 605 PGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHP 664 PG PP P PGA + + P P +G PL R IPP P Sbjct: 1103 PGVGIPPPPPL------PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL-PRVGIPPPP 1155 Query: 665 KVP-APFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVI 723 +P A PPP P + P P L + P P P PP P + P P + Sbjct: 1156 PLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGM 1215 Query: 724 SKDQSP-PPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPA 776 +P PP PPP PPPP P + Q + PPP P+ Sbjct: 1216 GIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLPS 1269 Score = 48.9 bits (115), Expect = 3e-05 Identities = 90/348 (25%), Positives = 124/348 (35%), Gaps = 56/348 (16%) Query: 641 APSDRSGPQILTPLG-DRFVIPPHPKV-PAPFSPPPSKPRSPNPAAPALAAPAVVPGPVS 698 AP PQ LG DRF++ P AP SP + AL+A + +P ++ Sbjct: 234 APPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQ---------ALSALSDLPESLA 284 Query: 699 TTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAP--SA 756 PQ PP+P P+ E+P + Q P S P P E AP A Sbjct: 285 AEPREPQQPPSPGG--LPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGA 342 Query: 757 SETAEEPLQD-----PNWPPPPPPAPE-EQDLSMADFPPPEEAFFSVASPEPAGPSGSPE 810 +T EE +D P P APE +D PEE E GP +P Sbjct: 343 GDTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEE--------EAQGPD-APA 393 Query: 811 LVSSPAASSSSATALQIQPPGSP------DPPPAPPAPAPASSAPGHVAKLPQKEPVGCS 864 S P + + S + P +P + P +P S +P ++ ++ S Sbjct: 394 AASLPGSPAPSQRCFKPYPLITPCYIKTTTRQLSSPNHSP-SQSPNQSPRIKRRPEPSLS 452 Query: 865 KGGGPPREDVGAPLVTPS-----LLQMVRLRSVGAPGGAPTPALGPSA----------PQ 909 +G V AP + R GA TP +G SA Sbjct: 453 RGSRTALASVAAPAKKHRADGGLAAGLSRSADWTEELGARTPRVGGSAHLLERGVASDSG 512 Query: 910 KPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPE 957 + AL+ +AS PA + G E L S Q NGPPE Sbjct: 513 GGVSPALAAKASGAPAAADGFQNVF----TGRTLLEKLFSQQENGPPE 556 >gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] Length = 416 Score = 122 bits (306), Expect = 2e-27 Identities = 119/412 (28%), Positives = 143/412 (34%), Gaps = 78/412 (18%) Query: 493 KLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAGAAPCPP 552 K + PP PP + +G P GP PP P + Q P P GG++ G P Sbjct: 46 KPQGPPSPPGKPQGPPPQGGNQPQGP---PPPPGKPQGP-----PPQGGNKPQGPPP--- 94 Query: 553 NPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPK 612 PG + PP +++ SP S G P GPP PGK Q P Sbjct: 95 -----------PGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP 143 Query: 613 PERVTSLRSP------------GASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVI 660 P+ + P G + S S S P P + PQ P Sbjct: 144 PQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPP------P 197 Query: 661 PPHPKVPAPFS-------PPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTT 713 P P+ P P PPP KP+ P P + A P PQ PP PQ Sbjct: 198 PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSP------PGKPQGPP-PQGG 250 Query: 714 LTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPP- 772 P P K Q PPP PPPP K + S S ++ P P PPP Sbjct: 251 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQ 310 Query: 773 -------PPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATAL 825 PPP P PPP+ P P P G P P S S +A Sbjct: 311 GGNQPQGPPPPP-----GKPQGPPPQGGNKPQGPPPPGKPQGPP-----PQGGSKSRSAR 360 Query: 826 QIQPPGSPDPPPAPPAPAPASSAP--GHVAKLPQKEPVGCSKGGGPPREDVG 875 PPG P PP P P G + PQ P G + GPPR G Sbjct: 361 --SPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAG--QPQGPPRPPQG 408 Score = 113 bits (282), Expect = 1e-24 Identities = 122/471 (25%), Positives = 145/471 (30%), Gaps = 109/471 (23%) Query: 579 SPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSS 638 SPS + G P GPP+ PGK Q P P+ + P Sbjct: 28 SPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGP---------------- 71 Query: 639 DPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVS 698 P P GP PP PPP KP+ P P +P PG Sbjct: 72 PPPPGKPQGP------------PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPG--- 116 Query: 699 TTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASE 758 PQ PP PQ P P K Q PPP PPPP K + + S Sbjct: 117 ----KPQGPP-PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSR 171 Query: 759 TAEEPLQDPNWPPP--------PPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPE 810 ++ P P PPP PPP P + PPP+ P P P G P Sbjct: 172 SSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ-----GPPPQGGNKPQGPPPPGKPQGPPP 226 Query: 811 LVSSPAASSSSATALQIQPPGSPDPPPA---------PPAPAPASSAPGHVAKLPQKEPV 861 + + S+ S PPG P PP PP P P PQ P Sbjct: 227 QGDNKSQSARS-------PPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP 279 Query: 862 GCSKGGGPP---------REDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPL 912 G PP R G P P P G P P P KP Sbjct: 280 PGKPQGPPPQGGSKSRSSRSPPGKPQGPP-------------PQGGNQPQGPPPPPGKPQ 326 Query: 913 RRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASF 972 G P P G + S + S +P GPP+ E PQ P A Sbjct: 327 GPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPA-- 384 Query: 973 IFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPP 1023 G Q + P + + Q RPPQ + P PP Sbjct: 385 ----GGNPQQPQAPPAGQPQ--------------GPPRPPQGGR--PSRPP 415 Score = 90.5 bits (223), Expect = 8e-18 Identities = 95/354 (26%), Positives = 128/354 (36%), Gaps = 46/354 (12%) Query: 435 KGGSEGQPESSTASNSVVPPPQGGSGRGSPSG-----GSTAEASDTLSIRSS-GQLSGRS 488 +GG++ Q PPPQGG+ P G + + S RS G+ G Sbjct: 63 QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPP 122 Query: 489 VSL-RKLKRPPPPPRRTHSLHQRGLAVPDGP------LGLPPKPERKQQ-----PQLPR- 535 + + PPPPP + +G P GP G PP+ + K + P P+ Sbjct: 123 PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQG 182 Query: 536 PPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPP 595 PP GG++ G P P P G + PP P+ S + +P P Sbjct: 183 PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKP 242 Query: 596 KGLA--------GPPASPGKAQPPKPERVTSLRSP------------GASVSSSLTSLCS 635 +G GPP PGK Q P P+ + P G S S S S Sbjct: 243 QGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPG 302 Query: 636 SSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPP-SKPRSPNP-----AAPALAA 689 P P + PQ P + PP P PPP KP+ P P + A + Sbjct: 303 KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSP 362 Query: 690 PAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPP 743 P GP +PQ PP P ++P + Q PP PP P PP Sbjct: 363 PGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQG-PPRPPQGGRPSRPP 415 Score = 74.3 bits (181), Expect = 6e-13 Identities = 97/366 (26%), Positives = 111/366 (30%), Gaps = 120/366 (32%) Query: 704 PQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEP 763 PQ PP+P K Q PPP PPPP KP+ P Sbjct: 47 PQGPPSPP------------GKPQGPPPQGGNQPQGPPPPPGKPQ------------GPP 82 Query: 764 LQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSAT 823 Q N P PPP + Q PPP+ S P P G P+ P + Sbjct: 83 PQGGNKPQGPPPPGKPQG------PPPQ----GDKSRSPRSPPGKPQ---GPPPQGGN-- 127 Query: 824 ALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSL 883 QP G P PP P P P PQ P G PP+ D Sbjct: 128 ----QPQGPPPPPGKPQGPPPQGG------NKPQGPPPPGKPQGPPPQGDN--------- 168 Query: 884 LQMVRLRSVGAPGGAPT--PALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSL 941 + RS +P G P P G + PQ P P P G Sbjct: 169 ----KSRSSRSPPGKPQGPPPQGGNQPQGP---------PPPPGKPQG------------ 203 Query: 942 AASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLER-----PVSPETQADLQ 996 +P GPP P PQ P +G K Q R P P Q Q Sbjct: 204 --PPPQGGNKPQGPPP--PGKPQGPPP-------QGDNKSQSARSPPGKPQGPPPQGGNQ 252 Query: 997 RNLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEPLTAPPTNGLP 1056 Q PP P K P+ PPP G PPP P P PP G Sbjct: 253 -----------PQGPPPPPGK-PQGPPPQGGNKPQGPPPPGKPQGP-------PPQGGSK 293 Query: 1057 HTQDRT 1062 R+ Sbjct: 294 SRSSRS 299 Score = 54.7 bits (130), Expect = 5e-07 Identities = 69/285 (24%), Positives = 91/285 (31%), Gaps = 27/285 (9%) Query: 810 ELVSSPAASSSSATALQIQPPGSPDPPPAPPA-PAPASSAPGHVAKLPQKEPVGCSKGGG 868 E VS + S A Q PP + P PP+ P P PQ P K G Sbjct: 21 EDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQG 80 Query: 869 PPREDVGAPLVTP-------SLLQMVRLRSVGAPGGAP---------TPALGPSAPQKPL 912 PP + P P Q + RS +P G P P P P KP Sbjct: 81 PPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 140 Query: 913 RRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGP-------PEAEPRPPQS 965 G P P G + + + S +P GP P+ P PP Sbjct: 141 GPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGK 200 Query: 966 PASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPV 1025 P +K +P P Q D ++ A Q PP P+ PPP Sbjct: 201 PQGPPPQGGNKPQGPPPPGKPQGPPPQGD-NKSQSARSPPGKPQGPPPQGGNQPQGPPPP 259 Query: 1026 ARKPSVGVPPPASPSYPRAEPLTAPPTNGLPHTQDRTKRELAENG 1070 KP PPP + P+ P P P +++ + G Sbjct: 260 PGKPQ--GPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPG 302 Score = 50.4 bits (119), Expect = 9e-06 Identities = 57/215 (26%), Positives = 75/215 (34%), Gaps = 35/215 (16%) Query: 402 PQPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPESSTASNSVVPPPQGGSGR 461 P + + P D S S S G +GG++ Q PPPQGG+ Sbjct: 217 PPGKPQGPPPQGDNKSQSARSPPGKPQGPP--PQGGNQPQGPPPPPGKPQGPPPQGGNKP 274 Query: 462 ------GSPSGGSTAEASDTLSIRSS-GQLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAV 514 G P G S + S RS G+ G + PPPP Sbjct: 275 QGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPP------------- 321 Query: 515 PDGPLGLPP----KPERKQQPQLPR-PPTTGGSEGAGAAPCPPNPA--------NSWVPG 561 P P G PP KP+ P P+ PP GGS+ A P P N P Sbjct: 322 PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPP 381 Query: 562 LSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPK 596 GG+ + P++P Q G P+ PP+ Sbjct: 382 PPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPPQ 416 >gi|221139926 NHS-like 1 [Homo sapiens] Length = 1606 Score = 120 bits (301), Expect = 7e-27 Identities = 190/754 (25%), Positives = 274/754 (36%), Gaps = 136/754 (18%) Query: 383 HSASPASVRSLGRFSSVSSPQPRSRHPSSS-----SDTWSHSQSSDTIVSDGSTLSSKGG 437 H A+P SS S Q ++ + S D + S +D+ G+ +S G Sbjct: 569 HLATPGYSTPTSNMSSCSLDQTSNKEDAGSLYSEDHDGYCASVHTDSGHGSGNLCNSSDG 628 Query: 438 SEGQPESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRP 497 G P S + V GR + G + D + R++SL+K K+P Sbjct: 629 F-GNPRHSVINVFV--------GRAQKNQGDRSNYQD--------KSLSRNISLKKAKKP 671 Query: 498 PPPPRRTHSL------------------------HQRGLAVPDGPLGLPPKPER---KQQ 530 P PP RT SL H L++P G G P ++ Sbjct: 672 PLPPSRTDSLRRIPKKSSQCNGQVLNESLIATLQHSLQLSLP-GKSGSSPSQSPCSDLEE 730 Query: 531 PQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGT 590 P LPR + + P + G +P S E T P Y +G Sbjct: 731 PWLPRSRSQSTVSAGSSMTSATTPNVYSLCGATPSQSDTSSVKSEYT-DPWGYYIDYTGM 789 Query: 591 PTLPPKGLAGPPASPGKAQPPKP-------ERVTSLRSPGASVSSSLTSLCSSSSDPAPS 643 P G S G P R T + PG SV + S S +PS Sbjct: 790 QEDPGNPAGGCSTSSGVPTGNGPVRHVQEGSRATMPQVPGGSVKPKIMSPEKSHRVISPS 849 Query: 644 DRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDAS 703 Q TP + P P SP K + P P P + + +S++ S Sbjct: 850 SGYSSQSNTPTA----LTPVPVFLKSVSPANGKGK-PKPKVPERKSSLISSVSISSSSTS 904 Query: 704 PQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEP 763 S + + + T + P + +PPP P PS P P + P + P + P Sbjct: 905 LSSSTSTEGSGTMKKLDPAVGSPPAPPPPPVPSPPFPCPADRSPFLPPPPPVTDCSQGSP 964 Query: 764 L-QDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSA 822 L P +PPPPP A + F P + S P P+ SP L SP Sbjct: 965 LPHSPVFPPPPPEA-------LIPFCSPPDWCLS-----PPRPALSPILPDSP------- 1005 Query: 823 TALQIQPP--GSPDPPPAPP---------APAPASSAPGHVAKLPQKEPVGCSKGGGPPR 871 +L + PP S +PPPAPP P +S ++ + P + PP Sbjct: 1006 VSLPLPPPLLPSSEPPPAPPLDPKFMKDTRPPFTNSGQPESSRGSLRPPSTKEETSRPP- 1064 Query: 872 EDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLH 931 PL+T LQMV+LR V GA L Q+ + +PV AP L Sbjct: 1065 ----MPLITTEALQMVQLRPVRKNSGAEAAQLSERTAQE--------QRTPV-APQYHLK 1111 Query: 932 AAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLER--PVSP 989 + LK+ + + +E S +QP + P P +S S+G ER PVS Sbjct: 1112 PSAFLKSRN-STNEMESESQPASVTSSLPTPAKSS--------SQGDHGSAAERGGPVSR 1162 Query: 990 ETQADLQRNLVAELRSISEQRPPQAPKKSP-KAPPPVARKPS--VGVPPP-----ASPSY 1041 A AE R P P SP + PPP+++KP + VPPP P+ Sbjct: 1163 SPGAPSAGE--AEARPSPSTTP--LPDSSPSRKPPPISKKPKLFLVVPPPQKDFAVEPAE 1218 Query: 1042 PRAEPLTAPPT-----NGLPHTQDRTKRELAENG 1070 +E L A P+ G H+++ + A+ G Sbjct: 1219 NVSEALRAVPSPTTGEEGSVHSREAKESSAAQAG 1252 Score = 72.0 bits (175), Expect = 3e-12 Identities = 117/504 (23%), Positives = 185/504 (36%), Gaps = 93/504 (18%) Query: 399 VSSPQPRSR--HPSSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPESSTASNSVVPPPQ 456 + SP+ R PSS + S++ ++ T V S +G+P+ VP + Sbjct: 836 IMSPEKSHRVISPSSGYSSQSNTPTALTPVPVFLKSVSPANGKGKPKPK------VPERK 889 Query: 457 GGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPD 516 S+ S + S SG + ++ PPPPP VP Sbjct: 890 SSLISSVSISSSSTSLSSSTSTEGSGTMKKLDPAVGSPPAPPPPP------------VPS 937 Query: 517 GPLGLPPKPERKQQPQLPRPPTTGGSEGAG---AAPCPPNPANSWVPGLSPGG-SRRPPR 572 P P P + P PP T S+G+ + PP P + +P SP PPR Sbjct: 938 PPF---PCPADRSPFLPPPPPVTDCSQGSPLPHSPVFPPPPPEALIPFCSPPDWCLSPPR 994 Query: 573 SPERTLSPSSGYSSQSGTPTLP-----------PKGLAG----------PPASPGKAQPP 611 + P S S P LP PK + P +S G +PP Sbjct: 995 PALSPILPDSPVSLPLPPPLLPSSEPPPAPPLDPKFMKDTRPPFTNSGQPESSRGSLRPP 1054 Query: 612 KPERVTSLRSPGASVSSSLTSLC-------SSSSDPAP-SDRSGPQILTPLGDRFVIPPH 663 + TS R P +++ + +S ++ A S+R+ + TP+ ++ + P Sbjct: 1055 STKEETS-RPPMPLITTEALQMVQLRPVRKNSGAEAAQLSERTAQEQRTPVAPQYHLKPS 1113 Query: 664 PKVPAPFSP----PPSKPRSPNPAAPALA---------APAVVPGPVSTTDASP-----Q 705 + + S S+P S + P A + A GPVS + +P + Sbjct: 1114 AFLKSRNSTNEMESESQPASVTSSLPTPAKSSSQGDHGSAAERGGPVSRSPGAPSAGEAE 1173 Query: 706 SPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEV-VVEAPSASETAEEPL 764 + P+P TT P P PS PPP +KKP++ +V P + A EP Sbjct: 1174 ARPSPSTT---------------PLPDSSPS-RKPPPISKKPKLFLVVPPPQKDFAVEPA 1217 Query: 765 QDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATA 824 ++ + P+P + +E+ + A P G+ L A S S + Sbjct: 1218 ENVSEALRAVPSPTTGEEGSVHSREAKESSAAQAGSHATHP-GTSVLEGGAAGSMSPSRV 1276 Query: 825 LQIQPPGSPDPPPAPPAPAPASSA 848 P PD PAP PA ++ Sbjct: 1277 EANVPMVQPDVSPAPKQEEPAENS 1300 Score = 43.9 bits (102), Expect = 8e-04 Identities = 242/1122 (21%), Positives = 374/1122 (33%), Gaps = 238/1122 (21%) Query: 105 QDNVFFPSGRPPHLEELHTQAQEGLRSLQHQEKQKLNKGG------WDHGDTQSIQSS-- 156 Q+NVF P+ RPP +E+LH QA+ L+S+ +E KL G + G T + +S Sbjct: 41 QENVFLPTTRPPCVEDLHRQAKLNLKSVL-RECDKLRHDGYRSSQYYSQGPTFAANASPF 99 Query: 157 ---RTGPDEDNISFCSQTTSY----------------------------------VAESS 179 DE+ CS ++S E Sbjct: 100 CDDYQDEDEETDQKCSLSSSEEERFISIRRPKTPASSDFSDLNTQTNWTKSLPLPTPEEK 159 Query: 180 TAEDALSIRSEM--IQRKGSTFRPHDSFPKS----GKSGRRRR--ERRSTVLGLPQHVQK 231 + A ++++++ I G F S +S RR + +RR T+ G+P ++QK Sbjct: 160 MRQQAQTVQADVVPINITGENFDRQASLRRSLIYTDTLVRRPKKVKRRKTITGVPDNIQK 219 Query: 232 ELGLRNEREAPGTPRAPGARDAVRIPTVDGRPRGTSGMGARVSLQALEAEAEAGAETEAM 291 EL A GT G DA DG T + +L + AG +E Sbjct: 220 EL-------ASGT----GQDDA------DGHSVYTPDHYS--TLGRFNSCRSAGQRSET- 259 Query: 292 LQRHIDRVYRDDTFVGRSTGTRAPPLTRPMSLAVPGLTGGAGPAEPLSPAMSISPQATYL 351 RD + P + R + G+ G S MS+ + + Sbjct: 260 ---------RDSSCQTEDVKVVPPSMRRIRAQKGQGIAAQMGHFSGSSGNMSVLSDSAGI 310 Query: 352 SKLIPHAVLPPTVDVVALGRCSLRTLSRCSLHSASPASVRSLGRFSSVSSPQPRSR-HPS 410 V P +D A R+ +R ++ S P + +LG ++ R HP Sbjct: 311 -------VFPSRLDSDAGFHSLPRSGARANIQSLEP-RLGALGPAGDMNGTFLYQRGHPQ 362 Query: 411 SSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPES-------------STASNSVVPPPQG 457 + + +S T G+ L K ES +T S S++P Sbjct: 363 ADENLGHLGGASGT----GTLLRPKSQELRHFESENIMSPACVVSPHATYSTSIIPNATL 418 Query: 458 GSGR---GSPSGGSTAEASDTLSIRSSGQLSGRS--VSLRKLKRPPPPPRRTHSLHQRGL 512 S P+ S + S S ++ R +S +K P P R + + Sbjct: 419 SSSSEVIAIPTAQSAGQRESKSSGSSHARIKSRDHLISRHAVKGDPQSPGRHWNEGHATI 478 Query: 513 AVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPR 572 D P +P P + G+ P N N+ P + Sbjct: 479 LSQDLDPHSPGEPALLSLCDSAVPLNAPANRENGSQAMPYNCRNNLA---FPAHPQDVDG 535 Query: 573 SPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTS 632 E + S G+SS + + G+A P KP L +PG S +S S Sbjct: 536 KSESSYSGGGGHSSS--------EPWEYKSSGNGRASPLKPH----LATPGYSTPTSNMS 583 Query: 633 LCS----SSSDPAPSDRS----------------GPQILTPLGDRFVIPPH--------- 663 CS S+ + A S S G L D F P H Sbjct: 584 SCSLDQTSNKEDAGSLYSEDHDGYCASVHTDSGHGSGNLCNSSDGFGNPRHSVINVFVGR 643 Query: 664 -PKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTP---------QTT 713 K S K S N + P P P S TD+ + P ++ Sbjct: 644 AQKNQGDRSNYQDKSLSRNISLKKAKKP---PLPPSRTDSLRRIPKKSSQCNGQVLNESL 700 Query: 714 LTPLQESPVIS----KDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNW 769 + LQ S +S SP SP P P + + V A S+ +A PN Sbjct: 701 IATLQHSLQLSLPGKSGSSPSQSPCSDLEEPWLPRSRSQSTVSAGSSMTSA----TTPNV 756 Query: 770 PPPPPPAPEEQDLS--MADFPPPEEAF--FSVASPEPAGPSGSPELVSSPAASSSSATAL 825 P + D S +++ P + ++ +P P+G S + + Sbjct: 757 YSLCGATPSQSDTSSVKSEYTDPWGYYIDYTGMQEDPGNPAGGCSTSSGVPTGNGPVRHV 816 Query: 826 QIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQ 885 Q GS P P S P ++ P+K S G + +TP Sbjct: 817 Q---EGSRATMPQVPG---GSVKPKIMS--PEKSHRVISPSSGYSSQSNTPTALTP---V 865 Query: 886 MVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKAC-SLAAS 944 V L+SV +P G P+ P R++ + + + S+ L ++ + ++ Sbjct: 866 PVFLKSV-----SPANGKGKPKPKVPERKSSLISSVSISSSSTSLSSSTSTEGSGTMKKL 920 Query: 945 EGLSSAQPNGPPEAEPRPP-QSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAEL 1003 + + P PP P PP PA + F+ P P T D + Sbjct: 921 DPAVGSPPAPPPPPVPSPPFPCPADRSPFL-----------PPPPPVT--DCSQGSPLPH 967 Query: 1004 RSISEQRPPQA--PKKSPK----APPPVARKP-------SVGVPPPASPSYPRAEPLTAP 1050 + PP+A P SP +PP A P S+ +PPP PS +EP AP Sbjct: 968 SPVFPPPPPEALIPFCSPPDWCLSPPRPALSPILPDSPVSLPLPPPLLPS---SEPPPAP 1024 Query: 1051 PTNGLPHTQDRTKRELAENGGVLQLVGPEEKMGLPGSDSQKE 1092 P + P T+ +G PE G S KE Sbjct: 1025 PLD--PKFMKDTRPPFTNSG------QPESSRGSLRPPSTKE 1058 Score = 39.7 bits (91), Expect = 0.016 Identities = 96/403 (23%), Positives = 142/403 (35%), Gaps = 46/403 (11%) Query: 314 APPLT-RPMSLAVPGLTGGAGPAEPLSPAMSISPQATYLSKLIPHAVLPPTVDVVALGRC 372 APPL + M P T +P S S+ P +T P P + AL Sbjct: 1023 APPLDPKFMKDTRPPFTNSG---QPESSRGSLRPPSTKEETSRPPM---PLITTEALQMV 1076 Query: 373 SLRTLSRCSLHSASPASVRSLGRFSSVSSPQ----PRSRHPSSSSDTWSHSQSSDTIVSD 428 LR + + S A+ S R+ + +PQ P + S +S S+S V+ Sbjct: 1077 QLRPVRKNSGAEAAQLSERTAQEQRTPVAPQYHLKPSAFLKSRNSTNEMESESQPASVTS 1136 Query: 429 GSTLSSKGGSEGQPESSTASNSVVP----PPQGGSGRGSPSGGSTAEASDTLSIRSSGQL 484 +K S+G S+ V P G PS ST D+ R + Sbjct: 1137 SLPTPAKSSSQGDHGSAAERGGPVSRSPGAPSAGEAEARPSP-STTPLPDSSPSRKPPPI 1195 Query: 485 SGRSVSLRKLKRPPPPPRR------THSLHQRGLAVPD---GPLGLPPKPERKQQPQLPR 535 S + KL PPP++ ++ + AVP G G E K+ Sbjct: 1196 SKKP----KLFLVVPPPQKDFAVEPAENVSEALRAVPSPTTGEEGSVHSREAKESSAAQA 1251 Query: 536 P-----PTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGT 590 P T EG A P+ + VP + P S P + S +G +S Sbjct: 1252 GSHATHPGTSVLEGGAAGSMSPSRVEANVPMVQPDVSPAPKQEEPAENSADTGGDGESCL 1311 Query: 591 PTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQI 650 G AG P + A E L+ G + + ++ A RS ++ Sbjct: 1312 SQ--QDGAAGVPET--NAAGSSSEACDFLKEDGNDEVMTPSRPRTTEDLFAAIHRSKRKV 1367 Query: 651 LTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVV 693 L G R H + + PS P +P AAP+LA+P V Sbjct: 1368 L---GRRDSDDDHSR-----NHSPSPPVTPTGAAPSLASPKQV 1402 >gi|116284398 WAS/WASL interacting protein family, member 1 [Homo sapiens] Length = 503 Score = 119 bits (299), Expect = 1e-26 Identities = 122/420 (29%), Positives = 155/420 (36%), Gaps = 82/420 (19%) Query: 540 GGSEGAGAAPCPPNPANSWVPGL-------SPGGSRRPPRSPERTLSPSSGYSSQSGTPT 592 GGS G G P + +P L + G RPP P G S S P Sbjct: 89 GGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPP-------GGRSTSAKPF 141 Query: 593 LPPKGLAG-PPASPG-KAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQI 650 PP G P SPG ++ PP+P+R + P V S S+ P PS P+ Sbjct: 142 SPPSGPGRFPVPSPGHRSGPPEPQR-NRMPPPRPDVGSKPDSI----PPPVPST---PRP 193 Query: 651 LTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTP 710 + PP P P SP P+ P P AL ++ P+S++ PP P Sbjct: 194 IQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLP 253 Query: 711 QTTLTPLQESPVISKDQSPPPSPP----PSYH----PPPPPTKKPEVVVEAPSASETAEE 762 T L + P PPP PP PS H PPPPP V P S +++ Sbjct: 254 PTPSRALDDKP-------PPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQA 306 Query: 763 PLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSA 822 P PPPPPP+ PPP P +G +P L + SSS Sbjct: 307 P------PPPPPPS--------RPGPPP-------LPPSSSGNDETPRLPQRNLSLSSST 345 Query: 823 TALQIQPPGSPDPPPAPPA---PAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLV 879 L PG P P PP+ P P PG LP PV S+ G R Sbjct: 346 PPL--PSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPV--SRNGSTSR-------A 394 Query: 880 TPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKAC 939 P+ Q+ V +P P P L P P S A P P PS+ + + C Sbjct: 395 LPATPQLPSRSGVDSPRSGPRPPLPPDRP--------SAGAPPPPPPSTSIRNGFQDSPC 446 Score = 90.1 bits (222), Expect = 1e-17 Identities = 114/409 (27%), Positives = 151/409 (36%), Gaps = 79/409 (19%) Query: 390 VRSLGRFSSVSSPQPRSRHPSSSSDTWSHSQS-SDTIVSDGSTLSSKGGSEGQPE----S 444 V S G S PQ R+R P D S S + S + S + G P Sbjct: 152 VPSPGHRSGPPEPQ-RNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGP 210 Query: 445 STASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGR-------SVSLRKLKRP 497 S PPP G+ RG+ GG + S + SS S R S +L P Sbjct: 211 RQPSPGPTPPPFPGN-RGTALGGGSIRQSP---LSSSSPFSNRPPLPPTPSRALDDKPPP 266 Query: 498 PPPPRRTH-SLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPAN 556 PPPP S+H+ + P PP+ + P PRP S + A P PP P+ Sbjct: 267 PPPPVGNRPSIHREAVPPP------PPQNNKPPVPSTPRP-----SASSQAPPPPPPPSR 315 Query: 557 SWVPGLSPG--GSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPE 614 P L P G+ PR P+R LS SS TP LP G +GP P +PP P Sbjct: 316 PGPPPLPPSSSGNDETPRLPQRNLSLSSS------TPPLPSPGRSGPLPPPPSERPPPPV 369 Query: 615 RVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPP 674 R P RSGP +PP P V S Sbjct: 370 R-------------------------DPPGRSGP-----------LPPPPPVSRNGSTSR 393 Query: 675 SKPRSPN-PAAPALAAPAVVPGPVSTTD---ASPQSPPTPQTTL-TPLQESPVISKDQSP 729 + P +P P+ + +P P P D A PP P T++ Q+SP + +S Sbjct: 394 ALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESR 453 Query: 730 PPSPPPSYHPPPPP-TKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAP 777 P S PPP P + + + +E+ + PP PP P Sbjct: 454 FYFHPISDLPPPEPYVQTTKSYPSKLARNESRSGSNRRERGAPPLPPIP 502 Score = 89.0 bits (219), Expect = 2e-17 Identities = 118/419 (28%), Positives = 152/419 (36%), Gaps = 95/419 (22%) Query: 457 GGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKL----KRPPPPPRRTHSLHQRGL 512 GG G GS GG + +G RS + R RPP P S + Sbjct: 85 GGGGGGSFGGGGPPGLG---GLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPF 141 Query: 513 AVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPR 572 + P GP P +P P G PP P + +P P +P Sbjct: 142 SPPSGPGRFP----------VPSPGHRSG---------PPEPQRNRMPPPRPDVGSKPDS 182 Query: 573 SPE---RTLSPSSGYSSQSGTPTLPPKGLAGP-PASPGKAQPPKP-ERVTSLRSPGASVS 627 P T P G+P +P GP SPG PP P R T+L G S+ Sbjct: 183 IPPPVPSTPRPIQSSPHNRGSPPVP----GGPRQPSPGPTPPPFPGNRGTALG--GGSIR 236 Query: 628 SSLTSLCSSSSD-----PAPS---DRSGPQILTPLGDR-----FVIPPHP----KVPAPF 670 S S S S+ P PS D P P+G+R +PP P K P P Sbjct: 237 QSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPS 296 Query: 671 SPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPP 730 +P PS P P + P P P S++ + ++P PQ L+ +P + Sbjct: 297 TPRPSASSQAPPPPPPPSRPGPPPLPPSSS-GNDETPRLPQRNLSLSSSTPPLPSPGRSG 355 Query: 731 PSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPP 790 P PPP PPPP + P P S PL PPPPP S A Sbjct: 356 PLPPPPSERPPPPVRDP------PGRS----GPL------PPPPPVSRNGSTSRA----- 394 Query: 791 EEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPP--APPAPAPASS 847 A+P+ SG V SP + +PP PD P APP P P++S Sbjct: 395 -----LPATPQLPSRSG----VDSPRSGP--------RPPLPPDRPSAGAPPPPPPSTS 436 Score = 79.3 bits (194), Expect = 2e-14 Identities = 111/427 (25%), Positives = 144/427 (33%), Gaps = 102/427 (23%) Query: 623 GASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNP 682 G + + L S+++ S S P +L P G PFSPP R P P Sbjct: 101 GGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGG-------RSTSAKPFSPPSGPGRFPVP 153 Query: 683 AAPALAAPAV-----VPGPVSTTDASPQS-PPTPQTTLTPLQESPVISKDQSPPPSPPPS 736 + + P +P P + P S PP +T P+Q SP ++ P P P Sbjct: 154 SPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPH-NRGSPPVPGGPRQ 212 Query: 737 YHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFS 796 P P P P A + PL + PP P ++ D PPP Sbjct: 213 PSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPP----- 267 Query: 797 VASPEPAG--PSGSPELVSSPAASSSSATALQIQPPGSPDPP-PAPPAPAPASSAPGHVA 853 P P G PS E V P PP + PP P+ P P+ +S AP Sbjct: 268 ---PPPVGNRPSIHREAVPPP-------------PPQNNKPPVPSTPRPSASSQAPPPP- 310 Query: 854 KLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLR 913 PP G P + PS + G TP L PQ+ L Sbjct: 311 ---------------PPPSRPGPPPLPPS-----------SSGNDETPRL----PQRNL- 339 Query: 914 RALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFI 973 +LS P+P+P G S P P E P P + P Sbjct: 340 -SLSSSTPPLPSP-------------------GRSGPLPPPPSERPPPPVRDPPGR---- 375 Query: 974 FSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVGV 1033 S L PVS +L S S +P+ P+ P P R PS G Sbjct: 376 ----SGPLPPPPPVSRNGSTSRALPATPQLPSRSGV---DSPRSGPRPPLPPDR-PSAGA 427 Query: 1034 PPPASPS 1040 PPP PS Sbjct: 428 PPPPPPS 434 Score = 68.2 bits (165), Expect = 4e-11 Identities = 81/306 (26%), Positives = 112/306 (36%), Gaps = 61/306 (19%) Query: 754 PSASETAEEPLQDPNWPPP-PPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELV 812 P T+ +P P+ P P P+P + PPE + P P S P+ + Sbjct: 131 PGGRSTSAKPFSPPSGPGRFPVPSPGHRS------GPPEPQRNRMPPPRPDVGS-KPDSI 183 Query: 813 SSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPRE 872 P S+ GSP P P P+P + P P G + GGG R+ Sbjct: 184 PPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPP------PFPGNRGTALGGGSIRQ 237 Query: 873 DVGAPLVTPSLLQMVRLRSVGAPGGAPTPALG----PSAPQKPL--RRALSGRASPVPAP 926 +PL + S P PTP+ P P P+ R ++ A P P P Sbjct: 238 ---SPLSSSSPFS-------NRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPP 287 Query: 927 SSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERP 986 + + S S A P PP + P PP P S++ Sbjct: 288 QNN-----KPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSG--------------- 327 Query: 987 VSPETQADLQRNLVAELRSISEQRPP-QAPKKSPKAPPPVARKPSVGVPPPASPSYPRAE 1045 + ET QRNL S+S PP +P +S PPP + +P PPP R+ Sbjct: 328 -NDETPRLPQRNL-----SLSSSTPPLPSPGRSGPLPPPPSERP----PPPVRDPPGRSG 377 Query: 1046 PLTAPP 1051 PL PP Sbjct: 378 PLPPPP 383 Score = 53.9 bits (128), Expect = 8e-07 Identities = 73/295 (24%), Positives = 104/295 (35%), Gaps = 45/295 (15%) Query: 806 SGSPELVSSPAASSSSATALQ-IQPPGS------PDPPPAPPAPAPASSAPGHVAKLPQK 858 +G P+L S+ + S + + PPG P PP+ P P S PGH + P+ Sbjct: 106 AGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPS-PGHRSGPPEP 164 Query: 859 EPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSG 918 + PPR DVG+ P P P PS P +P++ + Sbjct: 165 Q----RNRMPPPRPDVGSK-----------------PDSIPPPV--PSTP-RPIQSSPHN 200 Query: 919 RASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGS 978 R SP P P + + G +A G P SP S + S Sbjct: 201 RGSP-PVPGGPRQPSPGPTPPPFPGNRG--TALGGGSIRQSPLSSSSPFSNRPPLPPTPS 257 Query: 979 RKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVG--VPPP 1036 R L + P P V SI + P P ++ K P P +PS PPP Sbjct: 258 RALDDKPPPPPPP--------VGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPP 309 Query: 1037 ASPSYPRAEPLTAPPTNGLPHTQDRTKRELAENGGVLQLVGPEEKMGLPGSDSQK 1091 P P P ++G T +R L+ + L P LP S++ Sbjct: 310 PPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSER 364 >gi|38373695 WAS/WASL interacting protein family, member 1 [Homo sapiens] Length = 503 Score = 119 bits (299), Expect = 1e-26 Identities = 122/420 (29%), Positives = 155/420 (36%), Gaps = 82/420 (19%) Query: 540 GGSEGAGAAPCPPNPANSWVPGL-------SPGGSRRPPRSPERTLSPSSGYSSQSGTPT 592 GGS G G P + +P L + G RPP P G S S P Sbjct: 89 GGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPP-------GGRSTSAKPF 141 Query: 593 LPPKGLAG-PPASPG-KAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQI 650 PP G P SPG ++ PP+P+R + P V S S+ P PS P+ Sbjct: 142 SPPSGPGRFPVPSPGHRSGPPEPQR-NRMPPPRPDVGSKPDSI----PPPVPST---PRP 193 Query: 651 LTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTP 710 + PP P P SP P+ P P AL ++ P+S++ PP P Sbjct: 194 IQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLP 253 Query: 711 QTTLTPLQESPVISKDQSPPPSPP----PSYH----PPPPPTKKPEVVVEAPSASETAEE 762 T L + P PPP PP PS H PPPPP V P S +++ Sbjct: 254 PTPSRALDDKP-------PPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQA 306 Query: 763 PLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSA 822 P PPPPPP+ PPP P +G +P L + SSS Sbjct: 307 P------PPPPPPS--------RPGPPP-------LPPSSSGNDETPRLPQRNLSLSSST 345 Query: 823 TALQIQPPGSPDPPPAPPA---PAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLV 879 L PG P P PP+ P P PG LP PV S+ G R Sbjct: 346 PPL--PSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPV--SRNGSTSR-------A 394 Query: 880 TPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKAC 939 P+ Q+ V +P P P L P P S A P P PS+ + + C Sbjct: 395 LPATPQLPSRSGVDSPRSGPRPPLPPDRP--------SAGAPPPPPPSTSIRNGFQDSPC 446 Score = 90.1 bits (222), Expect = 1e-17 Identities = 114/409 (27%), Positives = 151/409 (36%), Gaps = 79/409 (19%) Query: 390 VRSLGRFSSVSSPQPRSRHPSSSSDTWSHSQS-SDTIVSDGSTLSSKGGSEGQPE----S 444 V S G S PQ R+R P D S S + S + S + G P Sbjct: 152 VPSPGHRSGPPEPQ-RNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGP 210 Query: 445 STASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGR-------SVSLRKLKRP 497 S PPP G+ RG+ GG + S + SS S R S +L P Sbjct: 211 RQPSPGPTPPPFPGN-RGTALGGGSIRQSP---LSSSSPFSNRPPLPPTPSRALDDKPPP 266 Query: 498 PPPPRRTH-SLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPAN 556 PPPP S+H+ + P PP+ + P PRP S + A P PP P+ Sbjct: 267 PPPPVGNRPSIHREAVPPP------PPQNNKPPVPSTPRP-----SASSQAPPPPPPPSR 315 Query: 557 SWVPGLSPG--GSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPE 614 P L P G+ PR P+R LS SS TP LP G +GP P +PP P Sbjct: 316 PGPPPLPPSSSGNDETPRLPQRNLSLSSS------TPPLPSPGRSGPLPPPPSERPPPPV 369 Query: 615 RVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPP 674 R P RSGP +PP P V S Sbjct: 370 R-------------------------DPPGRSGP-----------LPPPPPVSRNGSTSR 393 Query: 675 SKPRSPN-PAAPALAAPAVVPGPVSTTD---ASPQSPPTPQTTL-TPLQESPVISKDQSP 729 + P +P P+ + +P P P D A PP P T++ Q+SP + +S Sbjct: 394 ALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESR 453 Query: 730 PPSPPPSYHPPPPP-TKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAP 777 P S PPP P + + + +E+ + PP PP P Sbjct: 454 FYFHPISDLPPPEPYVQTTKSYPSKLARNESRSGSNRRERGAPPLPPIP 502 Score = 89.0 bits (219), Expect = 2e-17 Identities = 118/419 (28%), Positives = 152/419 (36%), Gaps = 95/419 (22%) Query: 457 GGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKL----KRPPPPPRRTHSLHQRGL 512 GG G GS GG + +G RS + R RPP P S + Sbjct: 85 GGGGGGSFGGGGPPGLG---GLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPF 141 Query: 513 AVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPR 572 + P GP P +P P G PP P + +P P +P Sbjct: 142 SPPSGPGRFP----------VPSPGHRSG---------PPEPQRNRMPPPRPDVGSKPDS 182 Query: 573 SPE---RTLSPSSGYSSQSGTPTLPPKGLAGP-PASPGKAQPPKP-ERVTSLRSPGASVS 627 P T P G+P +P GP SPG PP P R T+L G S+ Sbjct: 183 IPPPVPSTPRPIQSSPHNRGSPPVP----GGPRQPSPGPTPPPFPGNRGTALG--GGSIR 236 Query: 628 SSLTSLCSSSSD-----PAPS---DRSGPQILTPLGDR-----FVIPPHP----KVPAPF 670 S S S S+ P PS D P P+G+R +PP P K P P Sbjct: 237 QSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPS 296 Query: 671 SPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPP 730 +P PS P P + P P P S++ + ++P PQ L+ +P + Sbjct: 297 TPRPSASSQAPPPPPPPSRPGPPPLPPSSS-GNDETPRLPQRNLSLSSSTPPLPSPGRSG 355 Query: 731 PSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPP 790 P PPP PPPP + P P S PL PPPPP S A Sbjct: 356 PLPPPPSERPPPPVRDP------PGRS----GPL------PPPPPVSRNGSTSRA----- 394 Query: 791 EEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPP--APPAPAPASS 847 A+P+ SG V SP + +PP PD P APP P P++S Sbjct: 395 -----LPATPQLPSRSG----VDSPRSGP--------RPPLPPDRPSAGAPPPPPPSTS 436 Score = 79.3 bits (194), Expect = 2e-14 Identities = 111/427 (25%), Positives = 144/427 (33%), Gaps = 102/427 (23%) Query: 623 GASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNP 682 G + + L S+++ S S P +L P G PFSPP R P P Sbjct: 101 GGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGG-------RSTSAKPFSPPSGPGRFPVP 153 Query: 683 AAPALAAPAV-----VPGPVSTTDASPQS-PPTPQTTLTPLQESPVISKDQSPPPSPPPS 736 + + P +P P + P S PP +T P+Q SP ++ P P P Sbjct: 154 SPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPH-NRGSPPVPGGPRQ 212 Query: 737 YHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFS 796 P P P P A + PL + PP P ++ D PPP Sbjct: 213 PSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPP----- 267 Query: 797 VASPEPAG--PSGSPELVSSPAASSSSATALQIQPPGSPDPP-PAPPAPAPASSAPGHVA 853 P P G PS E V P PP + PP P+ P P+ +S AP Sbjct: 268 ---PPPVGNRPSIHREAVPPP-------------PPQNNKPPVPSTPRPSASSQAPPPP- 310 Query: 854 KLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLR 913 PP G P + PS + G TP L PQ+ L Sbjct: 311 ---------------PPPSRPGPPPLPPS-----------SSGNDETPRL----PQRNL- 339 Query: 914 RALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFI 973 +LS P+P+P G S P P E P P + P Sbjct: 340 -SLSSSTPPLPSP-------------------GRSGPLPPPPSERPPPPVRDPPGR---- 375 Query: 974 FSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVGV 1033 S L PVS +L S S +P+ P+ P P R PS G Sbjct: 376 ----SGPLPPPPPVSRNGSTSRALPATPQLPSRSGV---DSPRSGPRPPLPPDR-PSAGA 427 Query: 1034 PPPASPS 1040 PPP PS Sbjct: 428 PPPPPPS 434 Score = 68.2 bits (165), Expect = 4e-11 Identities = 81/306 (26%), Positives = 112/306 (36%), Gaps = 61/306 (19%) Query: 754 PSASETAEEPLQDPNWPPP-PPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELV 812 P T+ +P P+ P P P+P + PPE + P P S P+ + Sbjct: 131 PGGRSTSAKPFSPPSGPGRFPVPSPGHRS------GPPEPQRNRMPPPRPDVGS-KPDSI 183 Query: 813 SSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPRE 872 P S+ GSP P P P+P + P P G + GGG R+ Sbjct: 184 PPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPP------PFPGNRGTALGGGSIRQ 237 Query: 873 DVGAPLVTPSLLQMVRLRSVGAPGGAPTPALG----PSAPQKPL--RRALSGRASPVPAP 926 +PL + S P PTP+ P P P+ R ++ A P P P Sbjct: 238 ---SPLSSSSPFS-------NRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPP 287 Query: 927 SSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERP 986 + + S S A P PP + P PP P S++ Sbjct: 288 QNN-----KPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSG--------------- 327 Query: 987 VSPETQADLQRNLVAELRSISEQRPP-QAPKKSPKAPPPVARKPSVGVPPPASPSYPRAE 1045 + ET QRNL S+S PP +P +S PPP + +P PPP R+ Sbjct: 328 -NDETPRLPQRNL-----SLSSSTPPLPSPGRSGPLPPPPSERP----PPPVRDPPGRSG 377 Query: 1046 PLTAPP 1051 PL PP Sbjct: 378 PLPPPP 383 Score = 53.9 bits (128), Expect = 8e-07 Identities = 73/295 (24%), Positives = 104/295 (35%), Gaps = 45/295 (15%) Query: 806 SGSPELVSSPAASSSSATALQ-IQPPGS------PDPPPAPPAPAPASSAPGHVAKLPQK 858 +G P+L S+ + S + + PPG P PP+ P P S PGH + P+ Sbjct: 106 AGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPS-PGHRSGPPEP 164 Query: 859 EPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSG 918 + PPR DVG+ P P P PS P +P++ + Sbjct: 165 Q----RNRMPPPRPDVGSK-----------------PDSIPPPV--PSTP-RPIQSSPHN 200 Query: 919 RASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGS 978 R SP P P + + G +A G P SP S + S Sbjct: 201 RGSP-PVPGGPRQPSPGPTPPPFPGNRG--TALGGGSIRQSPLSSSSPFSNRPPLPPTPS 257 Query: 979 RKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVG--VPPP 1036 R L + P P V SI + P P ++ K P P +PS PPP Sbjct: 258 RALDDKPPPPPPP--------VGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPP 309 Query: 1037 ASPSYPRAEPLTAPPTNGLPHTQDRTKRELAENGGVLQLVGPEEKMGLPGSDSQK 1091 P P P ++G T +R L+ + L P LP S++ Sbjct: 310 PPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSER 364 >gi|110349719 titin isoform N2-A [Homo sapiens] Length = 33423 Score = 114 bits (285), Expect = 5e-25 Identities = 132/498 (26%), Positives = 182/498 (36%), Gaps = 84/498 (16%) Query: 591 PTLPPKGLAGPPASPGKAQPPK--PERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGP 648 P PPKG P K PPK P +V + P A V + P + P Sbjct: 10436 PKAPPKG----PEISEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVP 10491 Query: 649 QILTP--LGDRFVIP----PHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDA 702 P L + V+P P P P +PPP P +P P P VP P Sbjct: 10492 PTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVP--VPPP-----K 10544 Query: 703 SPQSPPT--PQTTLTPLQESPVIS----KDQSPPPSPP-------PSYHPPPPPTKKPEV 749 P+ PPT P+ + E V K +SPPP P P P P KKPEV Sbjct: 10545 KPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEV 10604 Query: 750 V-VEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPP---PEEAFFSVASPEPAGP 805 V+ P E +E + + P PPP PE + + P PE+ P+P P Sbjct: 10605 TPVKVP---EAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESP 10661 Query: 806 SGSPELVSSP---AASSSSATALQIQPPGSPDPPPAPPA-PAPASSAPGHVAKLPQKEPV 861 PE+ P A A ++ P +P PP P P AP VAK P+ PV Sbjct: 10662 P--PEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPV 10719 Query: 862 GCSKGGGPPREDVGAPLVTPSL------------LQMVRLRSVGAPGGAPTP-ALGPSAP 908 + + PLV P ++V + V P P A P P Sbjct: 10720 KVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVP 10779 Query: 909 QKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPAS 968 +KP+ A PVP + V + +A E ++ + P AE P+ P Sbjct: 10780 KKPVLEEKP--AVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPP- 10836 Query: 969 TASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARK 1028 P PE + ++ E + ++P P K P+ P V K Sbjct: 10837 -----------------PAVPEEP----KKIIPEKKVPVIKKPEAPPPKEPE-PEKVIEK 10874 Query: 1029 PSVGV-PPPASPSYPRAE 1045 P + PPP P+ P+ + Sbjct: 10875 PKLKPRPPPPPPAPPKED 10892 Score = 97.8 bits (242), Expect = 5e-20 Identities = 144/583 (24%), Positives = 206/583 (35%), Gaps = 81/583 (13%) Query: 493 KLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAGAAPCPP 552 K+ P PP + + VP+ P + + E+ + P+ PR P T E P Sbjct: 10448 KIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVE-EKVRVPEEPRVPPTKVPEVLPPKEVVP 10506 Query: 553 NPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPP---------A 603 P P PP+ PE +P + P PPK PP A Sbjct: 10507 EKKVPVPPAKKPEAP--PPKVPE---APKEVVPEKK-VPVPPPKKPEVPPTKVPEVPKAA 10560 Query: 604 SPGK----AQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPA--PSDRSGPQILTPLGDR 657 P K A PPKPE SP V + + PA P + P + Sbjct: 10561 VPEKKVPEAIPPKPE------SPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPK 10614 Query: 658 FVIP----PHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTT 713 V+P P P P PP P P A P P +P P+SPP P+ Sbjct: 10615 EVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIP-------PKPESPP-PEVF 10666 Query: 714 LTPLQ---ESPVISKDQSPPPSPPPSYHPPP----PPTKKPEVVVEAPS-----ASETAE 761 P + E P + P P+ PP PP P K P VV + P E + Sbjct: 10667 EEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPK 10726 Query: 762 EPLQDPNWPPPPPPAPEEQDLSMADFPP---PEEAFFSVASPEPAGPSGSPELVSSPAAS 818 E + + P P PE + + P PE+ PE P+ PE+ P Sbjct: 10727 EVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPE-VPPAKVPEVPKKPVLE 10785 Query: 819 SSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPL 878 A + P + PP P AP +++PV ++ P +V P Sbjct: 10786 EKPAVPV----PERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEP---EVPPPA 10838 Query: 879 VTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKA 938 V +++ + V P P+K + + + P P P + V+ K Sbjct: 10839 VPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKL-KPRPPPPPPAPPKEDVKEKI 10897 Query: 939 CSLAA-SEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQR 997 L A + +P P + E P + P K RKL ER P+ + Sbjct: 10898 FQLKAIPKKKVPEKPQVPEKVELTPLKVPGG------EKKVRKLLPERKPEPKEEV---- 10947 Query: 998 NLVAELRSISEQRPPQA-PKKSPKAPPPVARKPSVGVPPPASP 1039 L+S+ +RP + PK PK V +KP+V PPP P Sbjct: 10948 ----VLKSVLRKRPEEEEPKVEPKKLEKV-KKPAVPEPPPPKP 10985 Score = 92.8 bits (229), Expect = 2e-18 Identities = 141/585 (24%), Positives = 198/585 (33%), Gaps = 106/585 (18%) Query: 495 KRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNP 554 K+P PP + + + + P +PPKPE P++P P E A P P Sbjct: 10544 KKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPE-SPPPEVPEAPKEVVPEKKVPAAPPKKP 10602 Query: 555 ANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPP--ASPGK----A 608 + V + P +P+ + P +PP + P A P K A Sbjct: 10603 EVTPV---------KVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEA 10653 Query: 609 QPPKPERVTSLRSPGASVSSSLTSLCSSSSDPA-----PSDRSGPQILTPLGDRFVIPPH 663 PPKPE SP V + + PA P + PQ+ P P Sbjct: 10654 IPPKPE------SPPPEVFEEPEEV-ALEEPPAEVVEEPEPAAPPQVTVPPKKPV---PE 10703 Query: 664 PKVPA-----PFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQ 718 K PA P PP P P P P VVP P++PP Sbjct: 10704 KKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVP-------KKPEAPPA--------- 10747 Query: 719 ESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPE 778 + P + K+ P P PP K PEV + P E P+ + PPP E Sbjct: 10748 KVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVP-KKPVLEEKPAVPVPERAESPPPEVYEE 10806 Query: 779 EQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPA 838 ++++ + PEE P P PE V PA +I P Sbjct: 10807 PEEIAPEEEIAPEEE-----KPVPVAEEEEPE-VPPPAVPEEPK---KIIPEKKVPVIKK 10857 Query: 839 PPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVT------------PSLLQM 886 P AP P P V + P+ +P PP+EDV + P + + Sbjct: 10858 PEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEK 10917 Query: 887 VRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAAS-E 945 V L + PGG +K +R+ L R P P L + +R + E Sbjct: 10918 VELTPLKVPGG-----------EKKVRKLLPER-KPEPKEEVVLKSVLRKRPEEEEPKVE 10965 Query: 946 GLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRS 1005 + P EP PP+ +K RK+ PE ++ Sbjct: 10966 PKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKI-------PEP---------TKVPE 11009 Query: 1006 ISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEPLTAP 1050 I P AP+ PK P A ++ PP P A P+T P Sbjct: 11010 IKPAIPLPAPEPKPK---PEAEVKTIKPPPVEPEPTPIAAPVTVP 11051 Score = 67.8 bits (164), Expect = 5e-11 Identities = 104/452 (23%), Positives = 152/452 (33%), Gaps = 60/452 (13%) Query: 660 IPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQE 719 +P K AP + P P+ P P L P P P+ P P P ++ Sbjct: 9965 VPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKV----PEVPKKP----VPEEK 10016 Query: 720 SPV-ISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPE 778 PV + K PP+ P P P KK V V AP E PP PE Sbjct: 10017 VPVPVPKKVEAPPAKVPEVPKKPVPEKK--VPVPAPKKVEA------------PPAKVPE 10062 Query: 779 EQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATAL---QIQPPGSPDP 835 + + P V +P P P E V P A L +I P P Sbjct: 10063 VPKKLIPEEKKPTPVPKKVEAPPPKVPK-KREPVPVPVALPQEEEVLFEEEIVPEEEVLP 10121 Query: 836 PPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPRED--------VGAPLVTPSLLQMV 887 P P LP++E + + PP E+ V V P + V Sbjct: 10122 EEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKV 10181 Query: 888 RLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGL 947 P AP P + +K + A P P + V K L E + Sbjct: 10182 -------PVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPE--VPKKVEEKRIILPKEEEV 10232 Query: 948 SSAQPNGPPEAEP----RPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAEL 1003 + PE EP P+ P S R ++ + PE + + + A Sbjct: 10233 LPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKKVEAPP 10292 Query: 1004 RSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEP---LTAPPTNGLPHTQD 1060 +S++ P + K P PV +K + PP P P+ P + P +P + Sbjct: 10293 AKVSKKIPEE------KVPVPVQKKEA---PPAKVPEVPKKVPEKKVLVPKKEAVPPAKG 10343 Query: 1061 RTKRELAENGGVLQLVGPEEKMGLPGSDSQKE 1092 RT E + Q V +E++ L +++ E Sbjct: 10344 RTVLEEKVSVAFRQEVVVKERLELEVVEAEVE 10375 Score = 64.3 bits (155), Expect = 6e-10 Identities = 95/386 (24%), Positives = 138/386 (35%), Gaps = 66/386 (17%) Query: 718 QESPVISKDQSPPPSPPPSYHPPPP--------PTKKPEVVVEAPSASETAEEPLQDPNW 769 +E V K ++PP P S PP P K+P V EE ++ P Sbjct: 10428 EEVEVFEKPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEE 10487 Query: 770 PPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAG--PSGSPELVSSPAASSSSATALQI 827 P PP + + PP+E P P P P V + + Sbjct: 10488 PRVPP-------TKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPV 10540 Query: 828 QPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMV 887 PP P+ PP P ++ P K+P+ P K PP E AP ++V Sbjct: 10541 PPPKKPEVPPTKVPEVPKAAVP--EKKVPEAIP---PKPESPPPEVPEAP------KEVV 10589 Query: 888 RLRSV-GAPGGAP--TPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAAS 944 + V AP P TP P AP + + + PVP P ++ A Sbjct: 10590 PEKKVPAAPPKKPEVTPVKVPEAP----KEVVPEKKVPVPPPKKPEVPPTKVPEVPKVA- 10644 Query: 945 EGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVS-----PETQADLQRNL 999 PEA P P+SP +F + ++ LE P + PE A Q + Sbjct: 10645 -----VPEKKVPEAIPPKPESPPPE---VFEE-PEEVALEEPPAEVVEEPEPAAPPQVTV 10695 Query: 1000 VAELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEPLTAPPTNGLPHTQ 1059 PP+ P KAP VA+KP +PP P P+ +P Sbjct: 10696 -----------PPKKPVPEKKAPAVVAKKPE--LPPVKVPEVPKEVVPEKKVPLVVPKKP 10742 Query: 1060 DRTKRELAENGGVLQLVGPEEKMGLP 1085 + ++ E V + V PE+K+ +P Sbjct: 10743 EAPPAKVPE---VPKEVVPEKKVAVP 10765 Score = 62.4 bits (150), Expect = 2e-09 Identities = 88/402 (21%), Positives = 137/402 (34%), Gaps = 49/402 (12%) Query: 495 KRPPPPPRRTHSLHQRGLAVPDGPLG----LPPKPERKQQPQLPRPPTTGGSEGAGAAPC 550 K+P P P++ + + VP P L PK E+ ++P P E P Sbjct: 9962 KKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPV 10021 Query: 551 P-----PNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSS-------QSGTPTLPPKGL 598 P P VP + P +P++ +P + + PT PK + Sbjct: 10022 PKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKV 10081 Query: 599 AGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRF 658 PP K + P P V + + P + P+ L + Sbjct: 10082 EAPPPKVPKKREPVPVPVALPQEEEVLFEEEI----------VPEEEVLPEEEEVLPEEE 10131 Query: 659 VIPPHPK--VPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSP---PTPQTT 713 + P + +P PP + P VP + P+ P P P+ Sbjct: 10132 EVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIK 10191 Query: 714 LTPLQESPVISKDQSPPPSPPPSYHPPPPPTK-----KPEVVVEAPSASETAEEPLQDPN 768 ++ VI K + PP+ P P K K E V+ E EEP+ + Sbjct: 10192 KKVTEKKVVIPKKEEAPPAKVPEV-PKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEE 10250 Query: 769 WPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQ 828 P PP E ++++ PP A PE P+ P+ V +P A S + Sbjct: 10251 IPEEPPSIEEVEEVA----PPRVPEVIKKAVPE--APTPVPKKVEAPPAKVSK------K 10298 Query: 829 PPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPP 870 P P P AP + P K+P+K+ + K PP Sbjct: 10299 IPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKEAVPP 10340 Score = 61.2 bits (147), Expect = 5e-09 Identities = 91/391 (23%), Positives = 123/391 (31%), Gaps = 62/391 (15%) Query: 663 HPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQES-- 720 H + PPP P P AP AP +P V P +P P+ P+ E Sbjct: 9275 HVAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKV-----EPPAPKVPEVPKKPVPEEKK 9329 Query: 721 --PVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPE 778 PV K+ + PP P P P K P V + A PP PE Sbjct: 9330 PVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEA---------------PPAKVPE 9374 Query: 779 EQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPA 838 Q + EE V E + P PE+ P + PP Sbjct: 9375 VQKGVVT-----EEKITIVTQREESPPPAVPEIPKKKVPEERKPV-----PRKEEEVPPP 9424 Query: 839 PPAPA-PASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGG 897 P PA P P + PV +K PPR +V V + + Sbjct: 9425 PKVPALPKKPVPEEKVAV----PVPVAKKAPPPRAEVSKKTVVEEKRFVAEEK------- 9473 Query: 898 APTPALGPSAPQK--PLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGP 955 L + PQ+ R +S S V + E A+ Sbjct: 9474 -----LSFAVPQRVEVTRHEVSAEEE---WSYSEEEEGVSISVYREEEREEEEEAEVT-E 9524 Query: 956 PEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAP 1015 E P + I SK E E + L+ + A++ + P+AP Sbjct: 9525 YEVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQEKKIVLKPKIPAKIEEPPPAKVPEAP 9584 Query: 1016 KK---SPKAPPPVARKPSVGVPPPASPSYPR 1043 KK K P PV +K VPPP P P+ Sbjct: 9585 KKIVPEKKVPAPVPKKEK--VPPPKVPEEPK 9613 Score = 53.9 bits (128), Expect = 8e-07 Identities = 100/439 (22%), Positives = 143/439 (32%), Gaps = 103/439 (23%) Query: 662 PHPKVPAPFSPPPSKPRSPNPAAPALAAP-AVVPGPVSTTDASPQSPPTPQTTLTPLQES 720 P P P P P P+KP++P A P VP P+ P P P+ +E Sbjct: 9792 PIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPI-PKKLKPPPPKVPEEPKKVFEEK 9850 Query: 721 PVIS--KDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPE 778 IS K + + P + P KP+ VV A E P ++ P P P+ Sbjct: 9851 IRISITKREKEQVTEPAAKVP-----MKPKRVV----AEEKVPVPRKEVAPPVRVPEVPK 9901 Query: 779 EQDLSMADFPPPEEAFFS---VASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDP 835 E + PEE F V E E + T ++ P Sbjct: 9902 ELE--------PEEVAFEEEVVTHVEEYLVEEEEEYIHE---EEEFITEEEVVPVIPVKV 9950 Query: 836 PPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAP 895 P P P P P V K + P + P E V P++ P + Sbjct: 9951 PEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKV--PVLIPKKEK---------- 9998 Query: 896 GGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGP 955 P PA P P+KP+ PVP P + P Sbjct: 9999 ---PPPAKVPEVPKKPVPE----EKVPVPVPK-----------------------KVEAP 10028 Query: 956 PEAEPRPPQSPASTASFIFSKGSRKLQLERP----VSPETQADLQRNLVAELRSISEQRP 1011 P P P+ P +K+ + P P ++ + L+ E E++P Sbjct: 10029 PAKVPEVPKKPVP---------EKKVPVPAPKKVEAPPAKVPEVPKKLIPE-----EKKP 10074 Query: 1012 PQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEPL-----TAPPTNGLPHTQDRTKREL 1066 PKK PP V +K P P + P+ E + P LP ++ E Sbjct: 10075 TPVPKKVEAPPPKVPKKRE---PVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEE- 10130 Query: 1067 AENGGVLQLVGPEEKMGLP 1085 + V PEE+ LP Sbjct: 10131 -------EEVLPEEEEVLP 10142 Score = 47.8 bits (112), Expect = 6e-05 Identities = 55/204 (26%), Positives = 77/204 (37%), Gaps = 45/204 (22%) Query: 640 PAPSDRSGPQILTPLG-DRFVIPPHPKVP-APFSP-PPSKPRSPNPAAPALAAPAV---- 692 P ++ P+ + P+ + V PP PKVP P P P K P P A P V Sbjct: 9289 PELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPPKVPEVP 9348 Query: 693 --------VPGPVSTTDASPQS--PPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPP 742 +P PV+ +P + P + +T + + V +++SPPP+ P P Sbjct: 9349 KKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEI-----P 9403 Query: 743 PTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEP 802 K PE P E PPPP P ++ P PEE VA P P Sbjct: 9404 KKKVPEERKPVPRKEEEV----------PPPPKVP-----ALPKKPVPEE---KVAVPVP 9445 Query: 803 AGPSGSPELVSSPAASSSSATALQ 826 P P A S T ++ Sbjct: 9446 VAKKAPP-----PRAEVSKKTVVE 9464 Score = 47.0 bits (110), Expect = 1e-04 Identities = 76/348 (21%), Positives = 107/348 (30%), Gaps = 103/348 (29%) Query: 724 SKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEE---------PLQDPNWPPPPP 774 S ++ P P PPPP K V+ + S EE + P P Sbjct: 9160 SHERKVPAKVPEKKAPPPPKVIKKPVIEKIEKTSRRMEEEKVQVTKVPEVSKKIVPQKPS 9219 Query: 775 PAPEEQDLSMADFPP--------PEEAFFSVASPEPAGPSGSPELVSSPAASSSSATAL- 825 P ++++ P EE F + E PE+ A+ Sbjct: 9220 RTPVQEEVIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKIHVAIS 9279 Query: 826 -QIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLL 884 +++PP P P P PAP AP + K + PP AP V Sbjct: 9280 KRVEPP--PKVPELPEKPAPEEVAPVPIPKKVE-----------PP-----APKV----- 9316 Query: 885 QMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAAS 944 P P+KP+ PVP P Sbjct: 9317 --------------------PEVPKKPVPE----EKKPVPVPKK---------------- 9336 Query: 945 EGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAE-- 1002 +P PP+ P P+ P +K E P P ++Q+ +V E Sbjct: 9337 ------EPAAPPKV-PEVPKKPVPEEKIPVPVAKKK---EAP--PAKVPEVQKGVVTEEK 9384 Query: 1003 ---LRSISEQRPPQAP----KKSPKAPPPVARKPSVGVPPPASPSYPR 1043 + E PP P KK P+ PV RK PPP P+ P+ Sbjct: 9385 ITIVTQREESPPPAVPEIPKKKVPEERKPVPRKEEEVPPPPKVPALPK 9432 Score = 43.5 bits (101), Expect = 0.001 Identities = 110/598 (18%), Positives = 171/598 (28%), Gaps = 125/598 (20%) Query: 521 LPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSP 580 +P K E ++P P E AP P VP PP+ PE P Sbjct: 9568 IPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEK---VP---------PPKVPEEPKKP 9615 Query: 581 SSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDP 640 +PPK + K + P P +VT L ++ + P Sbjct: 9616 VP-------EKKVPPKVI--------KMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPP 9660 Query: 641 APSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVS-- 698 P+ P + P + P + R ++ AP P P+ Sbjct: 9661 KARVPEEPKRAVPEEKVLKLKPKREEEPPAKVTEFRKRVVKEEKVSIEAPKREPQPIKEV 9720 Query: 699 TTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASE 758 T + T + +Q + + Y P + E E Sbjct: 9721 TIMEEKERAYTLEEEAVSVQREEEYEEYEEYDYKEFEEYEPTEEYDQYEEYEEREYERYE 9780 Query: 759 TAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAAS 818 EE + +P P P P PEE + PP + A PE P P+ + P Sbjct: 9781 EHEEYITEPEKPIPVKPVPEEPVPTKPKAPPAK--VLKKAVPEEKVPVPIPKKLKPP--- 9835 Query: 819 SSSATALQIQPPGSPDPP---------------PAPPAPAPASSAPGHVAKLPQKEPVGC 863 PP P+ P PA+ P ++ +E V Sbjct: 9836 ----------PPKVPEEPKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPV 9885 Query: 864 SKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPT----------------------- 900 PR++V P+ P + + + V T Sbjct: 9886 ------PRKEVAPPVRVPEVPKELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITE 9939 Query: 901 ----PALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPP 956 P + P+ P R+ + PVP P + PP Sbjct: 9940 EEVVPVIPVKVPEVP-RKPVPEEKKPVPVPK-----------------------KKEAPP 9975 Query: 957 EAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSIS--EQRPPQA 1014 P P+ P + K + + P P+ ++ V + + + P+ Sbjct: 9976 AKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEV 10035 Query: 1015 PKKS-PKAPPPVARKPSVGVPPPASPSYPR------AEPLTAPPTNGLPHTQDRTKRE 1065 PKK P+ PV V PP P P+ +P P P + KRE Sbjct: 10036 PKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKRE 10093 Score = 42.0 bits (97), Expect = 0.003 Identities = 32/105 (30%), Positives = 44/105 (41%), Gaps = 7/105 (6%) Query: 664 PKVPAPFS-PPPSK-PRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESP 721 PK+PA PPP+K P +P P PA P P P+ P P+ + + P Sbjct: 9566 PKIPAKIEEPPPAKVPEAPKKIVPEKKVPA--PVPKKEKVPPPKVPEEPKKPVPEKKVPP 9623 Query: 722 VISKDQSPPPSPPPSYHPPPPPTKKPEVVV---EAPSASETAEEP 763 + K + P P+ H +K V V EAP + EEP Sbjct: 9624 KVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEP 9668 Score = 38.1 bits (87), Expect = 0.046 Identities = 76/377 (20%), Positives = 124/377 (32%), Gaps = 55/377 (14%) Query: 531 PQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGT 590 P++P P E P P + P +P+ P + Sbjct: 9286 PKVPELPEKPAPEEVAPVPIP---------------KKVEPPAPKVPEVPKKPVPEEKKP 9330 Query: 591 PTLPPKGLAGPPASPGKAQPPKPER------VTSLRSPGASV---------SSSLTSLCS 635 +P K A PP P + P PE +P A V +T + Sbjct: 9331 VPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQ 9390 Query: 636 SSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPG 695 P P+ P+ P + P P+ PPP P P P VP Sbjct: 9391 REESPPPAVPEIPKKKVPEERK----PVPRKEEEVPPPPKVPALPKKPVP--EEKVAVPV 9444 Query: 696 PVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPS 755 PV+ P++ + +T ++E +++++ P + EV E Sbjct: 9445 PVAKKAPPPRAEVSKKTV---VEEKRFVAEEKL------SFAVPQRVEVTRHEVSAEEEW 9495 Query: 756 ASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSP 815 + EE + + EE++ + ++ EE V E S + + P Sbjct: 9496 SYSEEEEGVSISVY--REEEREEEEEAEVTEYEVMEEPEEYVV--EEKLHIISKRVEAEP 9551 Query: 816 AASSSSATALQIQPPGSP----DPPPAPPAPAPASSAPGH--VAKLPQKEPVGCSKGGGP 869 A + + P P +PPPA AP P A +P+KE V K Sbjct: 9552 AEVTERQEKKIVLKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEE 9611 Query: 870 PREDVGAPLVTPSLLQM 886 P++ V V P +++M Sbjct: 9612 PKKPVPEKKVPPKVIKM 9628 Score = 37.0 bits (84), Expect = 0.10 Identities = 35/107 (32%), Positives = 44/107 (41%), Gaps = 16/107 (14%) Query: 955 PPEAEPRPPQSPA--STASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPP 1012 PP P P+ PA A K K++ P PE + + V E E++P Sbjct: 9284 PPPKVPELPEKPAPEEVAPVPIPK---KVEPPAPKVPE----VPKKPVPE-----EKKPV 9331 Query: 1013 QAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEPLTAPPTNGLPHTQ 1059 PKK P APP V P VP P P A+ APP +P Q Sbjct: 9332 PVPKKEPAAPPKVPEVPKKPVPEEKIP-VPVAKKKEAPPAK-VPEVQ 9376 Score = 35.8 bits (81), Expect = 0.23 Identities = 38/115 (33%), Positives = 49/115 (42%), Gaps = 26/115 (22%) Query: 662 PHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESP 721 PH K P P PP K RSP P P++AA A + A QSP +P++ SP Sbjct: 250 PH-KTP-PRIPPKPKSRSPTP--PSIAAKAQL--------ARQQSP-------SPIRHSP 290 Query: 722 -VISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAP------SASETAEEPLQDPNW 769 + ++P PSP S P + P V +P AS A P P W Sbjct: 291 SPVRHVRAPTPSPVRSVSPAARISTSPIRSVRSPLLMRKTQASTVATGPEVPPPW 345 Score = 35.0 bits (79), Expect = 0.39 Identities = 28/105 (26%), Positives = 38/105 (36%), Gaps = 10/105 (9%) Query: 662 PHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPL---- 717 P +VP P P + P P A P ++P P + PP + +T Sbjct: 8938 PDSRVPIPTMPIRAVPPEEIPPVVAPPIPLLLPTP------EEKKPPPKRIEVTKKAVKK 8991 Query: 718 QESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEE 762 V++K + P PPPP T P E S AEE Sbjct: 8992 DAKKVVAKPKEMTPREEIVKKPPPPTTLIPAKAPEIIDVSSKAEE 9036 >gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapiens] Length = 673 Score = 113 bits (283), Expect = 9e-25 Identities = 165/717 (23%), Positives = 257/717 (35%), Gaps = 111/717 (15%) Query: 404 PRSRHPSSSSDTWSHSQSSDTIVSDGSTLS---SKGGSEGQPESSTASNSVVPPPQGGSG 460 P +R PS +S T + S +S T ++L+ S G P S AS + PP G Sbjct: 3 PPTRTPSRASPTRTPSTASLTGTPSRASLTGTPSTASLMGTP--SRASLTGTPPRASLKG 60 Query: 461 RGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDGPLG 520 S + + + +L+ S L R+ S+ LKR PP RT +L + L Sbjct: 61 TTSMASLMVSPSRASLTRMQSSSLLTRTPSMASLKRMPPRASRTRTLPRASLMRRPSTAS 120 Query: 521 LPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSP 580 L P R P + + AA P+ A+ +R PPR+ T++P Sbjct: 121 LTRSPSRASLTTTPSRASLSMTPSTAAALTMPSRASL---------TRTPPRA-SLTMTP 170 Query: 581 SSGYSSQSGTPTLPPKGLAGPPASPGKAQP---PKPERVTSLRSPGASVSSSLTSLCSSS 637 S+ +++ PP+ A P P + P P +T + S AS++ +L+ + Sbjct: 171 STASLTRT-----PPR--ASPTGMPSRTSPTGMPSTASLTKMDST-ASITRTLSRASPTG 222 Query: 638 SDPAPSDRSGPQ----ILTPLGDRFVIPPHPKVP---------------APFSPPPSKPR 678 + P S P + P + P P A + PS+P Sbjct: 223 TPPRASPTGSPPRASLSMMPSTALLIRTPPRASPTGMLSRTSLTKMDSTASITRTPSRPS 282 Query: 679 SPNP-AAPALAAPAVVPGPVS-----------------------TTDASPQSPPTPQTTL 714 + +P P+ A+ ++ P S +T + ++PP T Sbjct: 283 TASPTGTPSRASLSMTPSTASLMRMLPRASPTGMLSRTSLTKMDSTASISRTPPRASITR 342 Query: 715 TPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPP--- 771 TP + SP K + P+ PS P + + +AS T P P P Sbjct: 343 TPSRASPT-GKPSTASPTGTPSRASPTGSPSTASLTGLSSTASPTGTPPRASPTGTPSTA 401 Query: 772 ----PPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVS---SPAASSSSATA 824 PP A LS + +P A P+G+P S +P+ +S + T Sbjct: 402 SLTRKPPRASPTGMLSRTSITKMDSTASPTRTPPRASPTGTPPRASPTGTPSRASPTGTQ 461 Query: 825 LQIQPPGSPD--PPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPS 882 P GSP P P+ A + +P + +K E + TPS Sbjct: 462 STASPTGSPSTASPTGSPSTASPTGSPSRASLTRTPSRASLTK-----MESTASITRTPS 516 Query: 883 LLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPS-SGLHAAVRLKACSL 941 S +P G+P+ AL +P + RAS PS + L R Sbjct: 517 RASPTWTPSTASPTGSPSTALAMGSPSRAALTRTPSRASLTRTPSRASLTTPSRASLTRT 576 Query: 942 AASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVA 1001 ++ L+ P+ P P +S + +K + R Sbjct: 577 PSTVLLTRMPPSASPTGMPSRTSPTGMPSSALLTKMDSTASITR---------------T 621 Query: 1002 ELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASP--SYPRAEPLTAPPTNGLP 1056 R+ + PP+A SP PP R G PP ASP + PRA P T P+ P Sbjct: 622 PPRASPTETPPRA---SPTGTPP--RASPTGTPPRASPTGTPPRASP-TGTPSRASP 672 Score = 79.0 bits (193), Expect = 2e-14 Identities = 150/682 (21%), Positives = 232/682 (34%), Gaps = 70/682 (10%) Query: 234 GLRNEREAPGTPRAPGARDAVRIPTVDGRP-----RGTSGMGA------RVSLQALEAEA 282 G + GTP ++ G P +GT+ M + R SL +++ + Sbjct: 24 GTPSRASLTGTPSTASLMGTPSRASLTGTPPRASLKGTTSMASLMVSPSRASLTRMQSSS 83 Query: 283 E-AGAETEAMLQRHIDRVYRDDTFVGRSTGTRAPPLTRPMSLAVPGLTGGAGPAE----P 337 + A L+R R R T S R + S + LT A P Sbjct: 84 LLTRTPSMASLKRMPPRASRTRTLPRASLMRRPSTASLTRSPSRASLTTTPSRASLSMTP 143 Query: 338 LSPAMSISPQATYLSKLIPHAVLPPTVDVVALGRCSLRTLSRCSLHSASPASVRSLGRFS 397 + A P L++ P A L T +L R R SP + S + Sbjct: 144 STAAALTMPSRASLTRTPPRASLTMTPSTASLTRTPPRASPTGMPSRTSPTGMPSTASLT 203 Query: 398 SVSSPQPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSSKGGS--------EGQPESSTASN 449 + S +R S +S T + ++S T ++LS + P + Sbjct: 204 KMDSTASITRTLSRASPTGTPPRASPTGSPPRASLSMMPSTALLIRTPPRASPTGMLSRT 263 Query: 450 SVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPPPPRRTHSLHQ 509 S+ S +PS STA + T S S + +R L R P T L + Sbjct: 264 SLTKMDSTASITRTPSRPSTASPTGTPSRASLSMTPSTASLMRMLPRASP----TGMLSR 319 Query: 510 RGLAVPDGPLGL---PPKPERKQQPQLPRP---PTTGGSEGAGAAPCPP-NPANSWVPGL 562 L D + PP+ + P P P+T G + P +P+ + + GL Sbjct: 320 TSLTKMDSTASISRTPPRASITRTPSRASPTGKPSTASPTGTPSRASPTGSPSTASLTGL 379 Query: 563 SPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSP 622 S S P +P R +S +GTP+ A P +A P TS+ Sbjct: 380 SSTAS--PTGTPPR--------ASPTGTPS-----TASLTRKPPRASPTGMLSRTSITKM 424 Query: 623 GASVSSSLTSLCSS--SSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSP 680 ++ S + T +S + P S P +P G + P P+ SP S + Sbjct: 425 DSTASPTRTPPRASPTGTPPRASPTGTPSRASPTGTQSTASPTGS-PSTASPTGSPSTAS 483 Query: 681 NPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPP 740 +P+ A+ P S T + T T TP + SP + + P P + Sbjct: 484 PTGSPSRASLTRTPSRASLT----KMESTASITRTPSRASPTWTPSTASPTGSPSTALAM 539 Query: 741 PPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASP 800 P++ + PS + P + P + PP + P Sbjct: 540 GSPSR--AALTRTPSRASLTRTPSRASLTTPSRASLTRTPSTVLLTRMPPSAS--PTGMP 595 Query: 801 EPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEP 860 P+G P SS + +TA + P P PP +P + P P P Sbjct: 596 SRTSPTGMP---SSALLTKMDSTASITRTPPRASPTETPPRASPTGTPP---RASPTGTP 649 Query: 861 VGCSKGGGPPREDVGAPLVTPS 882 S G PPR +P TPS Sbjct: 650 PRASPTGTPPR---ASPTGTPS 668 Score = 62.0 bits (149), Expect = 3e-09 Identities = 102/418 (24%), Positives = 155/418 (37%), Gaps = 79/418 (18%) Query: 337 PLSPAMSISPQATYLSKLIPHAVLPPTVDVVALGRCSLRTLSRCSLHSASPASVRSLGRF 396 P ++S++P L +++P A PT L R SL + + S +P S+ R Sbjct: 290 PSRASLSMTPSTASLMRMLPRA--SPTG---MLSRTSLTKMDSTASISRTPPRA-SITRT 343 Query: 397 SSVSSPQPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPESSTASNSVVPPPQ 456 S +SP + PS++S T + S++S T ST S G SSTAS + PP Sbjct: 344 PSRASPTGK---PSTASPTGTPSRASPT--GSPSTASLTG------LSSTASPTGTPPR- 391 Query: 457 GGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPP--PPRRTHSLHQRGLAV 514 S G+PS S S +G LS S++ P PPR + Sbjct: 392 -ASPTGTPSTASLTRKPPRAS--PTGMLSRTSITKMDSTASPTRTPPRAS---------- 438 Query: 515 PDGPLGLPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPP--R 572 P G PP+ P P T + +P +P S G R R Sbjct: 439 ---PTGTPPRASPTGTPSRASPTGTQSTASPTGSPSTASPTGSPSTASPTGSPSRASLTR 495 Query: 573 SPER------------TLSPSSG---YSSQSGTPT-LPPKGLA-GPPA------------ 603 +P R T +PS ++ + +PT P LA G P+ Sbjct: 496 TPSRASLTKMESTASITRTPSRASPTWTPSTASPTGSPSTALAMGSPSRAALTRTPSRAS 555 Query: 604 ---SPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPA---PSDRSGPQILTPLGDR 657 +P +A P R + R+P + + + S + P+ P+ +LT + Sbjct: 556 LTRTPSRASLTTPSRASLTRTPSTVLLTRMPPSASPTGMPSRTSPTGMPSSALLTKMDST 615 Query: 658 FVIPPHPKVPAPFSPPP------SKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPT 709 I P +P PP + PR+ P A+P P S T ++ PT Sbjct: 616 ASITRTPPRASPTETPPRASPTGTPPRASPTGTPPRASPTGTPPRASPTGTPSRASPT 673 Score = 40.8 bits (94), Expect = 0.007 Identities = 113/502 (22%), Positives = 164/502 (32%), Gaps = 106/502 (21%) Query: 570 PPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSS 629 P R+P R SP+ S+ S T T L G P++ P +T P AS+ + Sbjct: 4 PTRTPSRA-SPTRTPSTASLTGTPSRASLTGTPSTASLMGTPSRASLTGT-PPRASLKGT 61 Query: 630 LTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAA 689 TS+ S P+ + + Q + L + ++P S + PR+ P+ A+ Sbjct: 62 -TSMASLMVSPSRASLTRMQSSSLLTRTPSMASLKRMPPRASRTRTLPRASLMRRPSTAS 120 Query: 690 PAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEV 749 P S T +P ++TP + + ++ PP + + Sbjct: 121 LTRSPSRASLTT----TPSRASLSMTPSTAAALTMPSRASLTRTPP----------RASL 166 Query: 750 VVEAPSASETAEEPLQDPNWPPP---PPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPS 806 + +AS T P P P P P L+ D S ASP P Sbjct: 167 TMTPSTASLTRTPPRASPTGMPSRTSPTGMPSTASLTKMDSTASITRTLSRASPTGTPPR 226 Query: 807 GSPELVSSPAASSSS--ATALQIQPPGSPDPPPAPPAPAPASS-----APGHVAKLPQKE 859 SP S P AS S +TAL I+ P P +P +S + + + P + Sbjct: 227 ASPT-GSPPRASLSMMPSTALLIRTP----PRASPTGMLSRTSLTKMDSTASITRTPSR- 280 Query: 860 PVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGR 919 P S G P R + +TPS ++R+ P +PT L ++ K A R Sbjct: 281 PSTASPTGTPSRASLS---MTPSTASLMRM----LPRASPTGMLSRTSLTKMDSTASISR 333 Query: 920 ASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSR 979 P + + S A P G P SP T S GS Sbjct: 334 TPP-----------------RASITRTPSRASPTGKPSTA-----SPTGTPSRASPTGS- 370 Query: 980 KLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASP 1039 P T A L +S P G PP Sbjct: 371 ---------PST---------ASLTGLSSTASP------------------TGTPP---- 390 Query: 1040 SYPRAEPLTAPPTNGLPHTQDR 1061 RA P P T L R Sbjct: 391 ---RASPTGTPSTASLTRKPPR 409 >gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo sapiens] Length = 5537 Score = 112 bits (279), Expect = 2e-24 Identities = 155/600 (25%), Positives = 222/600 (37%), Gaps = 84/600 (14%) Query: 466 GGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVP---DGPLG-- 520 G + + D L + GQ G V+ + K P P L + G+ + + PL Sbjct: 378 GDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEE 437 Query: 521 ---LPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPN-PANSWVPGLSPGGSRRPPRSPER 576 LPP E P PT+ E + +P P PA+ L SR SP Sbjct: 438 MPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHL--SRPLEESP-- 493 Query: 577 TLSPSSGYSSQSGTPTLPP-KGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCS 635 LSP S S P P L P SP + PP P T L P Sbjct: 494 -LSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPP------------P 540 Query: 636 SSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPG 695 +S +P P L+P + P P+ PP P SP P ++ P Sbjct: 541 EASPLSPPFEESP--LSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASR 598 Query: 696 PVSTTDASPQSPPTPQTTLTPLQESPVIS-KDQSPPPSPPPSYHPPPPPTKKPEV--VVE 752 + SP SPP ++ L+P E+ +S + P SPPP P PP PEV + Sbjct: 599 LFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPP---PEVSRLSP 655 Query: 753 APSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELV 812 P S + P + P PP PEE S PPPE S SP P SP Sbjct: 656 LPVVSRLSPPPEESPLSPP-----PEESPTS----PPPEA---SRLSPPPEDSPTSPPPE 703 Query: 813 SSPAASSSSATALQIQPPGSP-DPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPR 871 SPA+ + + + SP P P P P S P H++ P++ + PR Sbjct: 704 DSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGP-HLSPRPEEPHLS-------PR 755 Query: 872 EDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLH 931 + P ++P A P L P P++P A+ P + G H Sbjct: 756 PE--EPHLSPQ---------------AEEPHLSPQ-PEEPCLCAVPEEPHLSP-QAEGPH 796 Query: 932 AAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPET 991 + + + L+ + +P+ P E P SP S + + RP Sbjct: 797 LSPQPEELHLSP----QTEEPHLSPVPE-EPCLSPQPEESHLSPQSEEPCLSPRPEESHL 851 Query: 992 QADLQRNLVAELRSISEQRPPQ--APKKSPKAPPP--VARKPSVGVPPPASPSYPRAEPL 1047 +L++ ++ + P Q AP++ P PPP + P +G P + P P PL Sbjct: 852 SPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPL 911 Score = 109 bits (273), Expect = 1e-23 Identities = 163/655 (24%), Positives = 226/655 (34%), Gaps = 90/655 (13%) Query: 442 PESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPPPP 501 PE+S S PPP+ P + + + +S S + PPP Sbjct: 621 PEASRLS----PPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPE 676 Query: 502 RRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPG 561 S + P P P + P P P + S +P P P P Sbjct: 677 ESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEE---PQ 733 Query: 562 LSPG--GSRRPPRSPERTLSP---SSGYSSQSGTPTLPPKGLAGPPASPGK-AQPPKPER 615 L P G PR E LSP S Q+ P L P+ P P A P +P Sbjct: 734 LCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQ-----PEEPCLCAVPEEPHL 788 Query: 616 VTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPS 675 P S L + +P S L+P + + P + P P Sbjct: 789 SPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEE 848 Query: 676 KPRSPN----PAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPP 731 SP P +P P PG + P PP + +L+PL P +S+ PP Sbjct: 849 SHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPL 908 Query: 732 SPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPP- 790 SP P P P + EP P PP P P + A PP Sbjct: 909 SPLPEELPLSP-----------------SGEPSLSPQLMPPDPLPPPLSPIITAAAPPAL 951 Query: 791 ------EEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQP---------PGSPDP 835 E F + +P P +P ++ +P + A +P PGSP Sbjct: 952 SPLGELEYPFGAKGDSDPESPLAAP-ILETPISPPPEANCTDPEPVPPMILPPSPGSPVG 1010 Query: 836 PPAP----PAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRS 891 P +P P P S H P CS PP PL PS L + + Sbjct: 1011 PASPILMEPLPPQCSPLLQHSLVPQNSPPSQCS----PP----ALPLSVPSPLSPIG-KV 1061 Query: 892 VGAPGGAPTPALGPSAPQKPLRRALSGRA-SPVPAPSSGLHAAVRLKACSLAASEGL--S 948 VG A + +P AL A SP+P+P L A +L GL Sbjct: 1062 VGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGED 1121 Query: 949 SAQPNG--PPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSI 1006 +A +G P ++P P Q+P S AS + KGS L ++P T + + E + Sbjct: 1122 TAPLDGIDAPGSQPEPGQTPGSLASEL--KGSPVLLDPEELAPVTPME----VYPECKQT 1175 Query: 1007 SEQRPPQAPKKSPKAP----PPVARKPSVG------VPPPASPSYPRAEPLTAPP 1051 + Q P ++ P+AP PP K + AS S+P +EPL P Sbjct: 1176 AGQGSPCEEQEEPRAPVAPTPPTLIKSDIVNEISNLSQGDASASFPGSEPLLGSP 1230 Score = 86.7 bits (213), Expect = 1e-16 Identities = 178/736 (24%), Positives = 250/736 (33%), Gaps = 161/736 (21%) Query: 437 GSEGQPESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGR-SVSLRKLK 495 G+ G P + A + P +P+G ST+ +D +G + G S LK Sbjct: 2111 GALGSPPPAAAPTIFIGSPT------TPAGLSTS--ADGFLKPPAGSVPGPDSPGELFLK 2162 Query: 496 RPPPPPRRTHSLHQRGLA--------VPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAGA 547 PP P + S GLA P P PP P P +PP G S GA Sbjct: 2163 LPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPA--QPPMLGASSRPGA 2220 Query: 548 APCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGK 607 P ++ PG R P +P+ L P P P G G + P Sbjct: 2221 GQ--PGEFHT----TPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVG-GGKASEPLL 2273 Query: 608 AQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQI--------------LTP 653 + PP E +L + +S S + S SG + LTP Sbjct: 2274 SPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTP 2333 Query: 654 -----------LGDRFVIPP-----------HPKV------PAPFSPPPSKPRSPNPAAP 685 LG R PP HP + P++ PP PR P P P Sbjct: 2334 RASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPR-PQPPPP 2392 Query: 686 ----ALAAPAVVPGPVSTTDASPQSPPTPQTTLTP-------LQESPVISKDQSP----- 729 AL ++ P S ASPQS + Q+ LTP SPV + QSP Sbjct: 2393 ESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSR 2452 Query: 730 PPSPPPSYHP-----PPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSM 784 PPS P S P PP + PEV +A S + T+ L +P P Sbjct: 2453 PPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTS---LGAGGFPAALPAG-------- 2501 Query: 785 ADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQ---PPGSPDPPPAPPA 841 P E V S +P P V SP + T ++ P +P PP Sbjct: 2502 ----PAGELHAKVPSGQP------PNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPV 2551 Query: 842 PAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTP 901 P P LP + G GP +G P T + G+P G + Sbjct: 2552 PQPG---------LPPPHGINSHFGPGP---TLGKPQSTNYTVATGNFHPSGSPLGPSSG 2599 Query: 902 ALGPSAPQKPLRRALSGRASPVPAPSSGL----HAAVRLKACS--LAASEGLSSAQPNGP 955 + G S PLR P PAP L H A + + + E + + Sbjct: 2600 STGESYGLSPLR---PPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSL 2656 Query: 956 PEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQR----- 1010 AE Q P + ++ ++ Q +R + +QRN + + + + Sbjct: 2657 ATAELPGTQDP-GMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVG 2715 Query: 1011 PPQAPKKSPKAP---------PPVA----RKPSVGVPPP-------ASPSYPRAEPLTAP 1050 PP + P +P P A + VG+PP S+P + L+ P Sbjct: 2716 PPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRP 2775 Query: 1051 PTNGLPHTQDRTKREL 1066 P P + D R+L Sbjct: 2776 PPPATPSSMDVNSRQL 2791 Score = 83.6 bits (205), Expect = 1e-15 Identities = 116/430 (26%), Positives = 157/430 (36%), Gaps = 104/430 (24%) Query: 657 RFVIPPHPKVPAPFSPP-PSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLT 715 R V H V + FSPP P + P A +A G T P+ P Q Sbjct: 359 RSVAEQHTPVCSRFSPPEPGDTPTDEPDALYVACQGQPKGG-HVTSMQPKEPGPLQCEAK 417 Query: 716 PL----------------QESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASET 759 PL +E P++ + P SPPP P PP PE +P E Sbjct: 418 PLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPP---PEASRLSPPPEEL 474 Query: 760 AEEPLQD------PNWPPPPPPAPEEQDLSMADFPPPEEAFFS------VASPEPAGPSG 807 PL + P P P PEE LS PPPE + FS ++ PE + PS Sbjct: 475 PASPLPEALHLSRPLEESPLSPPPEESPLS----PPPESSPFSPLEESPLSPPEESPPSP 530 Query: 808 SPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGG 867 + E SP +S + + P SP P P +P P +S ++ P++ P+ Sbjct: 531 ALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEAS---RLSPPPEESPMS----- 582 Query: 868 GPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPS 927 PP E +P S L P +P L P + PL SP P Sbjct: 583 PPPEESPMSPPPEASRL---------FPPFEESP-LSPPPEESPL--------SPPP--- 621 Query: 928 SGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPV 987 +A L+ S P PPE P P S S L + + Sbjct: 622 ---------EASRLSPPPEDSPMSP--PPEESPMSPPPEVSRLS--------PLPVVSRL 662 Query: 988 SPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAE-- 1045 SP + S PP P++SP +PPP A + + PP SP+ P E Sbjct: 663 SPPPEE-------------SPLSPP--PEESPTSPPPEASR--LSPPPEDSPTSPPPEDS 705 Query: 1046 PLTAPPTNGL 1055 P + PP + L Sbjct: 706 PASPPPEDSL 715 Score = 70.9 bits (172), Expect = 6e-12 Identities = 167/717 (23%), Positives = 221/717 (30%), Gaps = 151/717 (21%) Query: 328 LTGGAGPAEPLSPAMSISPQATYLSKLIPHAVLPPTVDVVALGRCSLRTLSRCSLHSASP 387 LT A EP SP + + PQ PP +A S + R ++ P Sbjct: 2331 LTPRASQVEPQSPGLGLRPQE------------PPPAQALAPSPPSHPDIFRPGSYT-DP 2377 Query: 388 ASVRSLGRFSSVSSPQPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPESSTA 447 + L +P+P+ P S S SD P+S ++ Sbjct: 2378 YAQPPL-------TPRPQPPPPESCCALPPRSLPSDPF----------SRVPASPQSQSS 2420 Query: 448 SNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRS--VSLRKLKRPPPPPR--R 503 S S + P + PS + S R + R L K RP PP + Sbjct: 2421 SQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFK 2480 Query: 504 THSLHQRGLAVPDGPLGLPPKPERKQQPQLP--RPPTTGGSEGAGAAPCPPNPANSWVPG 561 SL L P LP P + ++P +PP S G GA P+P P Sbjct: 2481 AGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQ 2540 Query: 562 LSPGGSRRPPRSPERTLSPSSGYSSQ------------------------SGTPTLPPKG 597 S +PP P+ L P G +S SG+P P G Sbjct: 2541 AVGEPSLKPP-VPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSG 2599 Query: 598 LAG------PPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQIL 651 G P P PP P+ S GAS S +TS DP Sbjct: 2600 STGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPG---------- 2649 Query: 652 TPLGDRFVIPPHPKVPAPFSPPPS-----KPRSPNPAAPAL-----------------AA 689 T +G P P S K R L AA Sbjct: 2650 TGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAA 2709 Query: 690 PAVVPGPVSTTDASPQSPPTPQTTL--TPLQESPVISKDQSPPPSP-------PPSYHP- 739 A GP + A P SP Q + TP + S PPS P S+ Sbjct: 2710 AAGAVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSD 2769 Query: 740 -----PPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDL---SMADFPPPE 791 PPPP + V + ++ Q +P P ++Q L A Sbjct: 2770 DRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSM 2829 Query: 792 EAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAPGH 851 S P GP + + SP A S+ ++ PG P P PA PA Sbjct: 2830 RFAMSARFPSTPGPELGRQALGSPLAGIST----RLPGPGEPVPGPAGPA---------Q 2876 Query: 852 VAKLPQKEPVGCSKGG------GPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGP 905 +L G GG GPP+ P P RL AP G A+ Sbjct: 2877 FIELRHNVQKGLGPGGTPFPGQGPPQR----PRFYPVSEDPHRL----APEGLRGLAVSG 2928 Query: 906 SAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRP 962 PQKP A P P ++ LH K +L L + P+ P P Sbjct: 2929 LPPQKP-------SAPPAPELNNSLHPTPHTKGPTLPTGLELVNRPPSSTELGRPNP 2978 Score = 65.5 bits (158), Expect = 3e-10 Identities = 95/383 (24%), Positives = 136/383 (35%), Gaps = 84/383 (21%) Query: 733 PPPSYHPPPPPTKKPEVVVEAPSA----SETAEEPLQDPNWPPPPPPAPEEQDLSMADFP 788 P P PPP P + + +P+ S +A+ L+ P P P +P E L + P Sbjct: 2108 PQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKL---P 2164 Query: 789 PPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSA 848 P A V S +P G A A ++P PP PP P+P + A Sbjct: 2165 PQVPA--QVPSQDPFG----------------LAPAYPLEPRFPTAPPTYPPYPSP-TGA 2205 Query: 849 PGHVAKLPQKEPVGCSKGG-------GPPREDVGAPLV-----TPSLLQMVRLRSVGAPG 896 P L G + G G PR P PSL + S G G Sbjct: 2206 PAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGG 2265 Query: 897 GAPTPALGPSAPQKPLRRALS------GRASP---------VPAPSSGLH---------- 931 G + L P R+AL G +SP V +PSSG H Sbjct: 2266 GKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPD 2325 Query: 932 ---AAVRLKACSLAASEGLSSAQPNGPPEAE---PRPPQSPASTASFIFSKGS-RKLQLE 984 A + +A + +P PP A+ P PP P IF GS + Sbjct: 2326 VFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPD-----IFRPGSYTDPYAQ 2380 Query: 985 RPVSPETQADLQRNLVA----ELRSISEQRPPQAPKKSPKAPPPVARKP---SVGVPPPA 1037 P++P Q + A L S R P +P+ + P+ +P P P Sbjct: 2381 PPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPV 2440 Query: 1038 SPSYPRAEPLTAPPTNGLPHTQD 1060 +P + +P + PP+ P ++D Sbjct: 2441 TPRFQSPDPYSRPPSR--PQSRD 2461 Score = 52.8 bits (125), Expect = 2e-06 Identities = 170/712 (23%), Positives = 246/712 (34%), Gaps = 134/712 (18%) Query: 383 HSASPASVRSLGRFSSVSSPQPRSRHPSSSSD-TWSHSQSSDTIVSDGSTLSSKGGSEGQ 441 H +SP + LG ++ + + P+ SS+ T S ++ G+T S G+ Sbjct: 4008 HFSSPGA---LGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGE 4064 Query: 442 PESSTASNSVV------PPPQGGSGRGSPSGGSTAEASDTLSIR------SSGQLSGRSV 489 + S + +S + P PQ S + P + +S+ S GQL S Sbjct: 4065 VKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSS 4124 Query: 490 SLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAGAAP 549 S + P H L Q +++ D P + QQP L RP G P Sbjct: 4125 S--EASSVP------HLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPM----QNNTGPQP 4172 Query: 550 CPPNPANSWVPGLSPGGSRRPP-------------RSPE-RTLSPSSGYSSQSGTPTLPP 595 P P GL PG P ++P+ R LSP Q+ L Sbjct: 4173 PKPGPVLQSGQGL-PGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQA---LLMQ 4228 Query: 596 KGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSL-CSSSSDPAPSDRSGPQILTPL 654 + L A + PP E PG S L C P ++GP L L Sbjct: 4229 RQLQQSQAV--RQTPPYQE-------PGTQTSPLQGLLGCQPQLGGFPGPQTGP--LQEL 4277 Query: 655 GDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTL 714 G P P+ P PR P P P + P + +SPQ P P Sbjct: 4278 G----AGPRPQGP---------PRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLP 4324 Query: 715 TPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDP--NWPPP 772 +P + P ++ Q PP P P PT +P +P+A++ A+ W PP Sbjct: 4325 SPSSQLP--TEAQLPPTHPGTP--KPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPP 4380 Query: 773 PPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQI--QPP 830 A ++ + P + PE + S E P A + + + +P Sbjct: 4381 DNLAETQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREANGEPI 4440 Query: 831 GSPDPPPAPPAPAPASSAPGHVA--KLPQKEPVGCSKGGGPP--REDVGAPLVTPSLLQM 886 G+P P S A GH+ KL + + V S G G R ++ + S L Sbjct: 4441 GAPGTSNHLLLAGPRSEA-GHLLLQKLLRAKNVQLSTGRGSEGLRAEINGHI--DSKLAG 4497 Query: 887 VRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRL--------KA 938 + + G P +A +KPL P P A+ RL K Sbjct: 4498 LEQKLQGTPSNKED-----AAARKPL----------TPKPKRVQKASDRLVSSRKKLRKE 4542 Query: 939 CSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFI----FSKG---SRKLQLER------ 985 + ASE L E P PA TA+F F G + + QL Sbjct: 4543 DGVRASEALLKQLKQ---ELSLLPLTEPAITANFSLFAPFGSGCPVNGQSQLRGAFGSGA 4599 Query: 986 -PVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPP-VARKPSVGVPP 1035 P P+ + L L + PP P P PPP V +K GV P Sbjct: 4600 LPTGPDYYSQL-------LTKNNLSNPPTPPSSLPPTPPPSVQQKMVNGVTP 4644 Score = 46.2 bits (108), Expect = 2e-04 Identities = 85/389 (21%), Positives = 124/389 (31%), Gaps = 68/389 (17%) Query: 698 STTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSAS 757 S T SPQ Q L P + + SP P T K + V+ +S Sbjct: 3981 SRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLL-----TGKEQNTVDPAVSS 4035 Query: 758 ETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAA 817 E E P P PE SMA P PS Sbjct: 4036 EATEGPSTHQGGPLAIGTTPE----SMA------------TEPGEVKPS----------- 4068 Query: 818 SSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAP 877 S + L +QP P P P+ P PG + Q + + GG + G+ Sbjct: 4069 LSGDSQLLLVQP--QPQPQPSSLQLQPPLRLPGQQQQ--QVSLLHTAGGGSHGQLGSGSS 4124 Query: 878 LVTPSLLQMVRLRSVGA---PGGAPTPALGPSAPQKPLRRALSGRASPVPA-PSSGLHAA 933 S+ ++ SV PG LGP P L R + P P P L + Sbjct: 4125 SEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPM--LERPMQNNTGPQPPKPGPVLQSG 4182 Query: 934 VRLKACSLAASEGLSSAQPNGP----PEAEPRPPQSPASTASFIFSKGSRKLQLERPVSP 989 L + + G AQ G P+ PQ + + + ++ Q R P Sbjct: 4183 QGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPP 4242 Query: 990 ETQADLQRNLV------------------AELRSISEQRPPQAPKKSPKAPPPVARKPSV 1031 + Q + + L+ + PQ P + P P ++ P + Sbjct: 4243 YQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVL 4302 Query: 1032 G----VPPPASPSYPRAEPLTAPPTNGLP 1056 G PPP+SP P+ P++ LP Sbjct: 4303 GPVHPTPPPSSPQEPKRPSQLPSPSSQLP 4331 Score = 45.1 bits (105), Expect = 4e-04 Identities = 86/394 (21%), Positives = 132/394 (33%), Gaps = 79/394 (20%) Query: 720 SPVISKDQ-SPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPE 778 S +++K+ S PP+PP S P PPP+ + ++V + E E P A Sbjct: 4608 SQLLTKNNLSNPPTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKD----------AAS 4657 Query: 779 EQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPA 838 +D A E + + P P E V + S + P Sbjct: 4658 ARDSERALRDTSEVKSLDLLAALPTPPHNQTEDVRMESDEDSDS------------PDSI 4705 Query: 839 PPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGA 898 PA +P S + P G R + ++P + + R P Sbjct: 4706 VPASSPESILGEEAPRFPHL---------GSGRWEQEDRALSPVIPLIPRASIPVFPDTK 4756 Query: 899 PTPALGPSAPQK-PLRRALSGRASPVPAPSSGLHAAVR-LKACSLAASEGLSSAQPNG-- 954 P ALG P K P+ G+ S V + AA + L +A +E LS PN Sbjct: 4757 PYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNLNGVMVAVAELLSMKIPNSYE 4816 Query: 955 -------------PPEAEPRPP--------------------QSPASTASFIFSKGSRKL 981 P + E P Q A + L Sbjct: 4817 VLFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQLDIL 4876 Query: 982 QLERPVSPETQADLQRNLVAELRSISEQR----PPQ--APKKSPKAPPPVA--RKPSVGV 1033 L + SP + Q + + ++ ++ PP+ +P SP AP P + +P V + Sbjct: 4877 SLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVEL 4936 Query: 1034 P--PPASPSYPRAEPLTAPPTNGLPHTQDRTKRE 1065 P P A P P PL + P + P + R E Sbjct: 4937 PTEPLAEPPVPSPLPLASSPESARPKPRARPPEE 4970 Score = 43.5 bits (101), Expect = 0.001 Identities = 102/434 (23%), Positives = 147/434 (33%), Gaps = 87/434 (20%) Query: 315 PPLTRPMSLAVPGLTGGAGPA-EPLSPAMSISPQATYLSKLIPHAVLPPTVDVVALGRCS 373 P L +P S TG P+ PL P+ + ++ LS L P +VLPP +L S Sbjct: 2570 PTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLS 2629 Query: 374 LRTLSRCSLHSASPASVR---SLGRFSSVSSPQ-PRSRHPSSS--SDTWSHSQ------- 420 R + SP R G SS+++ + P ++ P S S T Q Sbjct: 2630 HGASQRSGI--TSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLR 2687 Query: 421 --------SSDTIVSDGSTLSSKGGSEGQPESSTASNSVVPPPQGGSGRGSPSGGSTAEA 472 +T+ + T ++ G+ G P S A S P RG T + Sbjct: 2688 ELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPS--SPAFEQLSRGQTPFAGTQDK 2745 Query: 473 SDTLSI---RSSGQL--SGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDG---------- 517 S + + + SG + G S +L RPPPP + S+ + G Sbjct: 2746 SSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPATPS-SMDVNSRQLVGGSQAFYQRAPY 2804 Query: 518 PLGLPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERT 577 P LP + +++Q Q + A +A P P P + Sbjct: 2805 PGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPG--------------PELGRQAL 2850 Query: 578 LSPSSGYSSQSGTPTLPPKGLAGP------------------PASPGKAQPPKPERVTSL 619 SP +G S++ P P G AGP PG+ P +P Sbjct: 2851 GSPLAGISTRLPGPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVS 2910 Query: 620 RSPGASVSSSLTSLCSSSSDP-APSDRSGPQILTPLGDRFVIPPHPKVPA------PFSP 672 P L L S P PS P++ L PH K P + Sbjct: 2911 EDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSLHP----TPHTKGPTLPTGLELVNR 2966 Query: 673 PPSKPR--SPNPAA 684 PPS PNP A Sbjct: 2967 PPSSTELGRPNPLA 2980 Score = 41.2 bits (95), Expect = 0.005 Identities = 86/409 (21%), Positives = 124/409 (30%), Gaps = 91/409 (22%) Query: 497 PPPPPRRTHSLHQRGLAVPDGPLGLPPKPE---RKQQPQLPRPPTTGGSEGAGAAPCPPN 553 PP PP G+ P LG PK R + L + A P PP+ Sbjct: 4627 PPTPPPSVQQKMVNGVT-PSEELGEHPKDAASARDSERALRDTSEVKSLDLLAALPTPPH 4685 Query: 554 ---------------PANSWVPGLSPGG--SRRPPRSP----------ERTLSPSSGYSS 586 +S VP SP PR P +R LSP Sbjct: 4686 NQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRFPHLGSGRWEQEDRALSPVIPLIP 4745 Query: 587 QSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRS 646 ++ P P P + G P K T + G+ VS LT +++ + + Sbjct: 4746 RASIPVFPD---TKPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNLNGVMVA 4802 Query: 647 GPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALA----APAVVPGPVSTTDA 702 ++L+ P+ PA P K + P +P P + DA Sbjct: 4803 VAELLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDA 4862 Query: 703 SPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEE 762 P TL + + K +SP P PP + + + AP E Sbjct: 4863 V-----LPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEE---- 4913 Query: 763 PLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSA 822 P PPP+P +P PA P P Sbjct: 4914 --------PSPPPSP--------------------LAPSPASPPTEP------------- 4932 Query: 823 TALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPR 871 ++ P P P P+P P +S+P P+ P + PPR Sbjct: 4933 ---LVELPTEPLAEPPVPSPLPLASSPESARPKPRARPPEEGEDSRPPR 4978 Score = 36.6 bits (83), Expect = 0.13 Identities = 86/370 (23%), Positives = 127/370 (34%), Gaps = 58/370 (15%) Query: 517 GPLGLPPKPERKQQ----PQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGS----- 567 G LP P+ Q L PPT S P PP+ V G++P Sbjct: 4596 GSGALPTGPDYYSQLLTKNNLSNPPTPPSS--LPPTP-PPSVQQKMVNGVTPSEELGEHP 4652 Query: 568 --RRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGAS 625 R ER L +S S LP PP + + + + E SP + Sbjct: 4653 KDAASARDSERALRDTSEVKSLDLLAALPT-----PPHN--QTEDVRMESDEDSDSPDSI 4705 Query: 626 V-SSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSP--PPSKPRSPNP 682 V +SS S+ + P SG DR + P P +P P P +KP Sbjct: 4706 VPASSPESILGEEAPRFPHLGSGRW---EQEDRALSPVIPLIPRASIPVFPDTKPYG--- 4759 Query: 683 AAPALAAPAVVPG--PVSTTDASPQSPPTPQTTLTPLQ----ESPVISKDQSPPPSPPPS 736 A VPG PV+T + S + T++ +++ + P S Sbjct: 4760 -----ALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNLNGVMVAVAELLSMKIPNS 4814 Query: 737 YH------PPPPPTKKPEVVVEAPSASETAEE---PLQDPNWPPPPPPAPEEQDLSMADF 787 Y P T+ + E P E E P P+W ++ D + + Sbjct: 4815 YEVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWL-------KQFDAVLPGY 4867 Query: 788 PPPEEA-FFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPAS 846 + S+ E P + + S+ L PP P PPP+P AP+PAS Sbjct: 4868 TLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPAS 4927 Query: 847 SAPGHVAKLP 856 + +LP Sbjct: 4928 PPTEPLVELP 4937 Score = 33.5 bits (75), Expect = 1.1 Identities = 31/107 (28%), Positives = 40/107 (37%), Gaps = 19/107 (17%) Query: 955 PPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQA 1014 PPE P P AS S E P SP +A + R + E Sbjct: 452 PPEESPTSPPPEASRLS--------PPPEELPASPLPEA------LHLSRPLEESPLSPP 497 Query: 1015 PKKSPKAPPPVAR-----KPSVGVPPPASPSYPRAEPLTAPPTNGLP 1056 P++SP +PPP + + S PP SP P E +PP P Sbjct: 498 PEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASP 544 >gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 110 bits (274), Expect = 9e-24 Identities = 173/713 (24%), Positives = 241/713 (33%), Gaps = 146/713 (20%) Query: 370 GRCSLRTLSRCSLHSASPASVRSLGRFSSVSSPQPRSRHPSSSSDTWSHSQSSDTIVSDG 429 GR ++ + C +H + + + V P + D S S T S G Sbjct: 522 GRENILLCTDCRIHFKKYGELPPIEK--PVDPPPFMFKPVKEEDDGLSGKHSMRTRRSRG 579 Query: 430 STLSSKGGSEGQPESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSV 489 S + + G + QP S S + SGR SPS ST SS +V Sbjct: 580 SMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAAST----------SSNDSKAETV 629 Query: 490 --SLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAGA 547 S +K+K P +++ QR D ++ + ++ RP Sbjct: 630 KKSAKKVKEEASSPLKSNK-RQREKVASDTEEADRTSSKKTKTQEISRPN---------- 678 Query: 548 APCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGK 607 SPS G S + ++ +G + P Sbjct: 679 -------------------------------SPSEGEGESSDSRSVNDEGSSDPK----- 702 Query: 608 AQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVP 667 + S S S+ S + SD SD S Q + + P P Sbjct: 703 ----------DIDQDNRSTSPSIPSPQDNESD---SDSSAQQQMLQAQPPALQAPTGVTP 749 Query: 668 APFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSP--PTPQTTLTPLQESPVISK 725 AP S PP P+ P P P +A AV P T +P P PT T +Q++P + Sbjct: 750 APSSAPPGTPQLPTPG-PTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHP 808 Query: 726 DQSPPPSPPPSYHPPPPPTKKPEV-VVEAPSASETAEEPLQDPNWPPPPPPAPEE-QDLS 783 + P P PPP HP P P +P PSA A+ PL PP P Q Sbjct: 809 QRPPSPHPPP--HPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG-----PPGPHSLQAGP 861 Query: 784 MADFPPPEEAFFSVASPEPAGPSGSPELVSSPAAS--------SSSATALQIQPPGSPDP 835 + P P + F P G L +SPAA+ +S +ALQ Q P P Sbjct: 862 LLQHPGPPQPF----GLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQP 917 Query: 836 -PPAPPA-----PAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRL 889 PPAP A P P + P A K P S GP + A L P L+ + Sbjct: 918 LPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLS---GPSPFSMNANLPPPPALKPLSS 974 Query: 890 RSVGAPGGAPTPALG--------PSAPQKPLRRALSGRASPVPA--PSSGLHAAVRLKAC 939 S P A P L PS+P +P S P PA P +GLH Sbjct: 975 LSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPF 1034 Query: 940 SLAASEGLSSAQPNGPPEAEP-------RPPQSPASTASFIFSKGSRKLQLERPVSPETQ 992 + P GPP P PP P ++A S + + Sbjct: 1035 AQ------HPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAA-----------SG 1077 Query: 993 ADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPS-----VGVPPPASPS 1040 + L ++ + + P++PPP R PS V P AS S Sbjct: 1078 GSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQS 1130 Score = 105 bits (263), Expect = 2e-22 Identities = 182/773 (23%), Positives = 259/773 (33%), Gaps = 148/773 (19%) Query: 370 GRCSLRTLSRCSLHSASPASVRSLGRFSSVSSPQPRS-----------RHPSSSSDTWSH 418 G+ S+RT S +++RS GR +SP R+ R+ S++ T S+ Sbjct: 568 GKHSMRTRRS----RGSMSTLRS-GRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSN 622 Query: 419 SQSSDTIVSDGSTLSSKGGSE------------GQPESSTASNSVVPPPQGGSGRGSPSG 466 ++T+ + + S E + ++S Q S SPS Sbjct: 623 DSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSE 682 Query: 467 GSTAEASDTLSIRSSGQLSGRSVSLRKLKRPP--PPPRRTHS---------LHQRGLAVP 515 G E+SD+ S+ G + + P P P+ S + Q Sbjct: 683 GE-GESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPAL 741 Query: 516 DGPLGLPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRS-- 573 P G+ P P P P+ PT G + A A P +P S P + P + Sbjct: 742 QAPTGVTPAPS-SAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHI 800 Query: 574 -------PERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASV 626 P+R SP P P G AG P++P AQPP L G Sbjct: 801 QQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPP-------LHGQGPPG 853 Query: 627 SSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPP--SKPRSPNPAA 684 SL ++GP + HP P PF PP S+ ++P + Sbjct: 854 PHSL--------------QAGPLL-----------QHPGPPQPFGLPPQASQGQAPLGTS 888 Query: 685 PALAAPAV-VPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPP 743 PA A P + P S + Q PP Q PL +P+ PPP+ P P P Sbjct: 889 PAAAYPHTSLQLPASQSALQSQQPPREQ----PLPPAPLAMPHIKPPPTTPIPQLPAPQA 944 Query: 744 TKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFP---PPEEAFFSVASP 800 K P + S A N PPPP P LS P PP + P Sbjct: 945 HKHPPHLSGPSPFSMNA-------NLPPPPALKPLSS-LSTHHPPSAHPPPLQLMPQSQP 996 Query: 801 EPAGPSGSPELVSS-----PAASSSSATALQIQP----------PGSPDP--PPAPPAPA 843 P+ P+ P L S P AS Q+ P PG P P PP P+ + Sbjct: 997 LPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTS 1056 Query: 844 PASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPAL 903 + PG A+ P G + GG PL T + + L P P P Sbjct: 1057 TPPAGPGTSAQPPCS---GAAASGGSIAGGSSCPLPTVQIKEEA-LDDAEEPESPPPPPR 1112 Query: 904 GPSAP----QKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAE 959 PS P + S R A L LA S+ L+ + +A+ Sbjct: 1113 SPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSK-LAKKREEAIEKAK 1171 Query: 960 PRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSP 1019 Q K + + E+ E + + +R AE + + + P Sbjct: 1172 REAEQ-----------KAREEREREKEKEKEREREREREREAERAAKASSSAHEGRLSDP 1220 Query: 1020 KAPPPVARKPSVGVPPPASPSYPRAEPLTAPPTNGL--------PHTQDRTKR 1064 + P +PS PP + P P P T L PH T R Sbjct: 1221 QLSGPGHMRPSFEPPPTTIAAVP---PYIGPDTPALRTLSEYARPHVMSPTNR 1270 Score = 57.8 bits (138), Expect = 6e-08 Identities = 105/433 (24%), Positives = 148/433 (34%), Gaps = 66/433 (15%) Query: 660 IPP--HPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDAS-PQSPPTPQTTLTP 716 +PP P P PF P K + G +ST + + P +P +P Sbjct: 542 LPPIEKPVDPPPFMFKPVKEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTSP 601 Query: 717 LQESPVISKDQSPPPSPPPSYHPPPPPTKKP--EVVVEAPS------------ASETAE- 761 + E S SP + S KK +V EA S AS+T E Sbjct: 602 INEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEA 661 Query: 762 ----------EPLQDPNWPPPPP-PAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPE 810 + + PN P + + + ++ P++ S P+ PS P+ Sbjct: 662 DRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPS--PQ 719 Query: 811 LVSSPAASSSSATALQIQPPGSPDPPPAPPAPA------PASSAPGHVAKLPQKEPVGCS 864 S + SS+ LQ QPP P PAP+ P PG P G Sbjct: 720 DNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSP 779 Query: 865 KGGGPPREDVG--APLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASP 922 P + AP+ + Q L P P P P P +PL +G A Sbjct: 780 TASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPL----TGSAGQ 835 Query: 923 VPAPSSGLHAAVRLKACSLAASEGLSSA---QPNGPPEAEPRPPQSPASTASFIFSKGSR 979 APS HA L L + Q GPP+ PPQ+ S+G Sbjct: 836 PSAPS---HAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQA---------SQGQA 883 Query: 980 KLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPAS- 1038 L P + LQ L A ++ Q+PP ++ P P P+A P + PP Sbjct: 884 PLGTS-PAAAYPHTSLQ--LPASQSALQSQQPP---REQPLPPAPLA-MPHIKPPPTTPI 936 Query: 1039 PSYPRAEPLTAPP 1051 P P + PP Sbjct: 937 PQLPAPQAHKHPP 949 Score = 43.9 bits (102), Expect = 8e-04 Identities = 43/172 (25%), Positives = 66/172 (38%), Gaps = 26/172 (15%) Query: 927 SSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERP 986 SS ++ + +L A G++ A + PP P P +A+ + +GS + P Sbjct: 727 SSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTAS-QAP 785 Query: 987 VSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEP 1046 P+ A + QAP P+ PP PPP +P +P Sbjct: 786 NQPQ----------APTAPVPHTHIQQAPALHPQRPPSPH-------PPPHPSPHPPLQP 828 Query: 1047 LT------APPTNGLP--HTQDRTKRELAENGGVLQLVGPEEKMGLPGSDSQ 1090 LT + P++ P H Q + G +LQ GP + GLP SQ Sbjct: 829 LTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQ 880 >gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 110 bits (274), Expect = 9e-24 Identities = 173/713 (24%), Positives = 241/713 (33%), Gaps = 146/713 (20%) Query: 370 GRCSLRTLSRCSLHSASPASVRSLGRFSSVSSPQPRSRHPSSSSDTWSHSQSSDTIVSDG 429 GR ++ + C +H + + + V P + D S S T S G Sbjct: 522 GRENILLCTDCRIHFKKYGELPPIEK--PVDPPPFMFKPVKEEDDGLSGKHSMRTRRSRG 579 Query: 430 STLSSKGGSEGQPESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSV 489 S + + G + QP S S + SGR SPS ST SS +V Sbjct: 580 SMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAAST----------SSNDSKAETV 629 Query: 490 --SLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAGA 547 S +K+K P +++ QR D ++ + ++ RP Sbjct: 630 KKSAKKVKEEASSPLKSNK-RQREKVASDTEEADRTSSKKTKTQEISRPN---------- 678 Query: 548 APCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGK 607 SPS G S + ++ +G + P Sbjct: 679 -------------------------------SPSEGEGESSDSRSVNDEGSSDPK----- 702 Query: 608 AQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVP 667 + S S S+ S + SD SD S Q + + P P Sbjct: 703 ----------DIDQDNRSTSPSIPSPQDNESD---SDSSAQQQMLQAQPPALQAPTGVTP 749 Query: 668 APFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSP--PTPQTTLTPLQESPVISK 725 AP S PP P+ P P P +A AV P T +P P PT T +Q++P + Sbjct: 750 APSSAPPGTPQLPTPG-PTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHP 808 Query: 726 DQSPPPSPPPSYHPPPPPTKKPEV-VVEAPSASETAEEPLQDPNWPPPPPPAPEE-QDLS 783 + P P PPP HP P P +P PSA A+ PL PP P Q Sbjct: 809 QRPPSPHPPP--HPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG-----PPGPHSLQAGP 861 Query: 784 MADFPPPEEAFFSVASPEPAGPSGSPELVSSPAAS--------SSSATALQIQPPGSPDP 835 + P P + F P G L +SPAA+ +S +ALQ Q P P Sbjct: 862 LLQHPGPPQPF----GLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQP 917 Query: 836 -PPAPPA-----PAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRL 889 PPAP A P P + P A K P S GP + A L P L+ + Sbjct: 918 LPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLS---GPSPFSMNANLPPPPALKPLSS 974 Query: 890 RSVGAPGGAPTPALG--------PSAPQKPLRRALSGRASPVPA--PSSGLHAAVRLKAC 939 S P A P L PS+P +P S P PA P +GLH Sbjct: 975 LSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPF 1034 Query: 940 SLAASEGLSSAQPNGPPEAEP-------RPPQSPASTASFIFSKGSRKLQLERPVSPETQ 992 + P GPP P PP P ++A S + + Sbjct: 1035 AQ------HPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAA-----------SG 1077 Query: 993 ADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPS-----VGVPPPASPS 1040 + L ++ + + P++PPP R PS V P AS S Sbjct: 1078 GSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQS 1130 Score = 105 bits (263), Expect = 2e-22 Identities = 182/773 (23%), Positives = 259/773 (33%), Gaps = 148/773 (19%) Query: 370 GRCSLRTLSRCSLHSASPASVRSLGRFSSVSSPQPRS-----------RHPSSSSDTWSH 418 G+ S+RT S +++RS GR +SP R+ R+ S++ T S+ Sbjct: 568 GKHSMRTRRS----RGSMSTLRS-GRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSN 622 Query: 419 SQSSDTIVSDGSTLSSKGGSE------------GQPESSTASNSVVPPPQGGSGRGSPSG 466 ++T+ + + S E + ++S Q S SPS Sbjct: 623 DSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSE 682 Query: 467 GSTAEASDTLSIRSSGQLSGRSVSLRKLKRPP--PPPRRTHS---------LHQRGLAVP 515 G E+SD+ S+ G + + P P P+ S + Q Sbjct: 683 GE-GESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPAL 741 Query: 516 DGPLGLPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRS-- 573 P G+ P P P P+ PT G + A A P +P S P + P + Sbjct: 742 QAPTGVTPAPS-SAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHI 800 Query: 574 -------PERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASV 626 P+R SP P P G AG P++P AQPP L G Sbjct: 801 QQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPP-------LHGQGPPG 853 Query: 627 SSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPP--SKPRSPNPAA 684 SL ++GP + HP P PF PP S+ ++P + Sbjct: 854 PHSL--------------QAGPLL-----------QHPGPPQPFGLPPQASQGQAPLGTS 888 Query: 685 PALAAPAV-VPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPP 743 PA A P + P S + Q PP Q PL +P+ PPP+ P P P Sbjct: 889 PAAAYPHTSLQLPASQSALQSQQPPREQ----PLPPAPLAMPHIKPPPTTPIPQLPAPQA 944 Query: 744 TKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFP---PPEEAFFSVASP 800 K P + S A N PPPP P LS P PP + P Sbjct: 945 HKHPPHLSGPSPFSMNA-------NLPPPPALKPLSS-LSTHHPPSAHPPPLQLMPQSQP 996 Query: 801 EPAGPSGSPELVSS-----PAASSSSATALQIQP----------PGSPDP--PPAPPAPA 843 P+ P+ P L S P AS Q+ P PG P P PP P+ + Sbjct: 997 LPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTS 1056 Query: 844 PASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPAL 903 + PG A+ P G + GG PL T + + L P P P Sbjct: 1057 TPPAGPGTSAQPPCS---GAAASGGSIAGGSSCPLPTVQIKEEA-LDDAEEPESPPPPPR 1112 Query: 904 GPSAP----QKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAE 959 PS P + S R A L LA S+ L+ + +A+ Sbjct: 1113 SPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSK-LAKKREEAIEKAK 1171 Query: 960 PRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSP 1019 Q K + + E+ E + + +R AE + + + P Sbjct: 1172 REAEQ-----------KAREEREREKEKEKEREREREREREAERAAKASSSAHEGRLSDP 1220 Query: 1020 KAPPPVARKPSVGVPPPASPSYPRAEPLTAPPTNGL--------PHTQDRTKR 1064 + P +PS PP + P P P T L PH T R Sbjct: 1221 QLSGPGHMRPSFEPPPTTIAAVP---PYIGPDTPALRTLSEYARPHVMSPTNR 1270 Score = 57.8 bits (138), Expect = 6e-08 Identities = 105/433 (24%), Positives = 148/433 (34%), Gaps = 66/433 (15%) Query: 660 IPP--HPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDAS-PQSPPTPQTTLTP 716 +PP P P PF P K + G +ST + + P +P +P Sbjct: 542 LPPIEKPVDPPPFMFKPVKEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTSP 601 Query: 717 LQESPVISKDQSPPPSPPPSYHPPPPPTKKP--EVVVEAPS------------ASETAE- 761 + E S SP + S KK +V EA S AS+T E Sbjct: 602 INEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEA 661 Query: 762 ----------EPLQDPNWPPPPP-PAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPE 810 + + PN P + + + ++ P++ S P+ PS P+ Sbjct: 662 DRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPS--PQ 719 Query: 811 LVSSPAASSSSATALQIQPPGSPDPPPAPPAPA------PASSAPGHVAKLPQKEPVGCS 864 S + SS+ LQ QPP P PAP+ P PG P G Sbjct: 720 DNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSP 779 Query: 865 KGGGPPREDVG--APLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASP 922 P + AP+ + Q L P P P P P +PL +G A Sbjct: 780 TASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPL----TGSAGQ 835 Query: 923 VPAPSSGLHAAVRLKACSLAASEGLSSA---QPNGPPEAEPRPPQSPASTASFIFSKGSR 979 APS HA L L + Q GPP+ PPQ+ S+G Sbjct: 836 PSAPS---HAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQA---------SQGQA 883 Query: 980 KLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPAS- 1038 L P + LQ L A ++ Q+PP ++ P P P+A P + PP Sbjct: 884 PLGTS-PAAAYPHTSLQ--LPASQSALQSQQPP---REQPLPPAPLA-MPHIKPPPTTPI 936 Query: 1039 PSYPRAEPLTAPP 1051 P P + PP Sbjct: 937 PQLPAPQAHKHPP 949 Score = 43.9 bits (102), Expect = 8e-04 Identities = 43/172 (25%), Positives = 66/172 (38%), Gaps = 26/172 (15%) Query: 927 SSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERP 986 SS ++ + +L A G++ A + PP P P +A+ + +GS + P Sbjct: 727 SSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTAS-QAP 785 Query: 987 VSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEP 1046 P+ A + QAP P+ PP PPP +P +P Sbjct: 786 NQPQ----------APTAPVPHTHIQQAPALHPQRPPSPH-------PPPHPSPHPPLQP 828 Query: 1047 LT------APPTNGLP--HTQDRTKRELAENGGVLQLVGPEEKMGLPGSDSQ 1090 LT + P++ P H Q + G +LQ GP + GLP SQ Sbjct: 829 LTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQ 880 >gi|189181720 proteoglycan 4 isoform B [Homo sapiens] Length = 1363 Score = 109 bits (273), Expect = 1e-23 Identities = 153/683 (22%), Positives = 240/683 (35%), Gaps = 79/683 (11%) Query: 412 SSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPESSTASN---------SVVPPPQGGSGRG 462 SS + S S SS TI S+ +S E Q + N + PP +G G Sbjct: 125 SSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSG 184 Query: 463 SPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPPP-PRRTHSLHQRGLAVPDGPLGL 521 +G DT + + + + ++ K P P P + + + L V Sbjct: 185 LDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTV-----NK 239 Query: 522 PPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGS--RRPPRSPERTLS 579 E K+ + +T G E +A + + L+P +P E T Sbjct: 240 ETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTK 299 Query: 580 PSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSD 639 + + + TPT P + PAS +P ++ +P ++ S ++ + Sbjct: 300 GPALTTPKEPTPTTPKE-----PASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKE 354 Query: 640 PAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPP--PSKPRSPNPAAPALAAPAVVPGPV 697 PAP+ P TP + P K PAP + P+ P+ P P P AP P Sbjct: 355 PAPTTTKEPAPTTP---KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA 411 Query: 698 STTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSAS 757 TT P +P TP+ P + P + + P P+ P P P K+P A Sbjct: 412 PTTPKEP-TPTTPKEP-APTTKEPAPTTPKEPAPTAPKK--PAPTTPKEPAPTTPKEPAP 467 Query: 758 ETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAA 817 T +EP P P P P + + P P + +P+ P+ + E +P Sbjct: 468 TTTKEP--SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKE--PAPTT 523 Query: 818 SSSSATALQIQPPGSPDPPPAPPAPA-PASSAPGHVAKLPQKEPVGCSKGGGPPREDVGA 876 A +P + PAP P PA + A KEP + P Sbjct: 524 PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTP--- 580 Query: 877 PLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRL 936 +TP+ + + + P L P+ P++P + PAP++ Sbjct: 581 KKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP-----TPTTPEEPAPTTP------- 628 Query: 937 KACSLAASEGLSSAQPNGPPEAEPRPPQSPASTA----SFIFSKGSRKLQLERPV--SPE 990 AA P P E P P+ PA T + KG+ L+ P +P+ Sbjct: 629 ---KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPK 685 Query: 991 TQA--DLQRNLVAELRSISEQRP---------PQAPKK----SPKAPPPVARKPSVGV-- 1033 A +L E S + +P P PK+ +PK P P K + Sbjct: 686 KPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTL 745 Query: 1034 --PPPASPSYPRAEPLTAPPTNG 1054 P P +P P + L T G Sbjct: 746 KEPAPTTPKKPAPKELAPTTTKG 768 Score = 102 bits (253), Expect = 3e-21 Identities = 153/726 (21%), Positives = 239/726 (32%), Gaps = 82/726 (11%) Query: 403 QPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPESSTASNSVVPPPQGGSGRG 462 +P S P + T S + +T S + +P +T P+ + Sbjct: 316 EPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTT 375 Query: 463 SPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPP--PPRRTHSLHQRGLAVPDGPLG 520 + T S + + + + + K P P P T + + P Sbjct: 376 TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAP 435 Query: 521 LPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSP 580 PK P+ P P T E A P P P + P S P+ P T + Sbjct: 436 TTPKEPAPTAPKKPAPTTP--KEPAPTTPKEPAPTTTKEP------SPTTPKEPAPTTTK 487 Query: 581 SSGYSSQSGTPTLPPKGLAGPPA-SPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSD 639 S+ +++ PT P SP + P P T+ + P + ++ + Sbjct: 488 SAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP---TTPKEPAPTTPKKPAP--TTPKE 542 Query: 640 PAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPN---PAAPALAAPAVVPGP 696 PAP+ P P + P PK PAP +P + P +P P P AP P Sbjct: 543 PAPTTPKEP---APTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKP 599 Query: 697 VSTT--DASPQSP--PTPQTT-----LTPLQESPVISKDQSP--PPSPPPSYHPPPPPTK 745 TT + +P +P PTP T TP +P K+ +P P P P+ P PT Sbjct: 600 APTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT 659 Query: 746 KPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFP----------------- 788 E P TA L++P P PAP+E + P Sbjct: 660 PKETAPTTPKG--TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA 717 Query: 789 ---PPEEAFFSVASPEPAGPSGS-PELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAP 844 P E A + P P P G+ P + PA ++ A + P + P + + P Sbjct: 718 PTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP 777 Query: 845 ASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALG 904 A + P A KEP + P P T + + +P + Sbjct: 778 APTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDEST- 836 Query: 905 PSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQ 964 P +P +AL P++ AA + + + A + + PE P+ Sbjct: 837 PELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTT-TAKDKTTERDLRTTPETTTAAPK 895 Query: 965 SPASTASFIFSKGSRKLQLERP-VSPETQADLQRNLVAELRSIS---------------- 1007 TA+ K+ V+ T D + L++ + Sbjct: 896 MTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTE 955 Query: 1008 ------EQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEP-LTAPPTNGLPHTQD 1060 E P+ + KA P +KP+ P S P+ P + P T P Sbjct: 956 IMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMT 1015 Query: 1061 RTKREL 1066 T EL Sbjct: 1016 STMPEL 1021 Score = 84.7 bits (208), Expect = 4e-16 Identities = 108/479 (22%), Positives = 171/479 (35%), Gaps = 59/479 (12%) Query: 400 SSPQPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPESSTASNSVVPPPQ--G 457 ++ +P P + T + S + T +T S + +P +T P+ Sbjct: 469 TTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPA 528 Query: 458 GSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDG 517 + P+ + E + T + + + + P P+ T P Sbjct: 529 PTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET---------APTT 579 Query: 518 PLGLPPKPERKQQPQLP-RPPTTGGSEGAGAAPCPPNPANSWVPG------LSPGGSRRP 570 P L P K P P +P T E A P P P P +P + P Sbjct: 580 PKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEP 639 Query: 571 ----PRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASV 626 P+ P T ++ T PKG A P + + P P++ + Sbjct: 640 APTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA--PTTLKEPAPTTPKKPAPKELAPTTT 697 Query: 627 SSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRS------- 679 ++ C PAP+ G TP + P PK PAP +P + P + Sbjct: 698 KEPTSTTCDK---PAPTTPKGTAPTTP---KEPAPTTPKEPAPTTPKGTAPTTLKEPAPT 751 Query: 680 -PNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTT--LTPLQESPVISKDQSP--PPSPP 734 P AP AP GP STT P +P TP+ T TP + +P K +P P +PP Sbjct: 752 TPKKPAPKELAPTTTKGPTSTTSDKP-APTTPKETAPTTPKEPAPTTPKKPAPTTPETPP 810 Query: 735 P--SYHPPPPPTKKPEVVVEAP--SASETAEEPL--------QDPNWPPPPPPAPEEQDL 782 P S P TK+P + ++P S E + EP ++P P PA + ++ Sbjct: 811 PTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEM 870 Query: 783 -SMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSS---ATALQIQPPGSPDPPP 837 + A E + A P + E ++ ++ S AT Q+ + D P Sbjct: 871 TTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTP 929 >gi|67190163 proteoglycan 4 isoform A [Homo sapiens] Length = 1404 Score = 109 bits (273), Expect = 1e-23 Identities = 153/683 (22%), Positives = 240/683 (35%), Gaps = 79/683 (11%) Query: 412 SSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPESSTASN---------SVVPPPQGGSGRG 462 SS + S S SS TI S+ +S E Q + N + PP +G G Sbjct: 166 SSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSG 225 Query: 463 SPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPPP-PRRTHSLHQRGLAVPDGPLGL 521 +G DT + + + + ++ K P P P + + + L V Sbjct: 226 LDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTV-----NK 280 Query: 522 PPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGS--RRPPRSPERTLS 579 E K+ + +T G E +A + + L+P +P E T Sbjct: 281 ETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTK 340 Query: 580 PSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSD 639 + + + TPT P + PAS +P ++ +P ++ S ++ + Sbjct: 341 GPALTTPKEPTPTTPKE-----PASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKE 395 Query: 640 PAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPP--PSKPRSPNPAAPALAAPAVVPGPV 697 PAP+ P TP + P K PAP + P+ P+ P P P AP P Sbjct: 396 PAPTTTKEPAPTTP---KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA 452 Query: 698 STTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSAS 757 TT P +P TP+ P + P + + P P+ P P P K+P A Sbjct: 453 PTTPKEP-TPTTPKEP-APTTKEPAPTTPKEPAPTAPKK--PAPTTPKEPAPTTPKEPAP 508 Query: 758 ETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAA 817 T +EP P P P P + + P P + +P+ P+ + E +P Sbjct: 509 TTTKEP--SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKE--PAPTT 564 Query: 818 SSSSATALQIQPPGSPDPPPAPPAPA-PASSAPGHVAKLPQKEPVGCSKGGGPPREDVGA 876 A +P + PAP P PA + A KEP + P Sbjct: 565 PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTP--- 621 Query: 877 PLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRL 936 +TP+ + + + P L P+ P++P + PAP++ Sbjct: 622 KKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP-----TPTTPEEPAPTTP------- 669 Query: 937 KACSLAASEGLSSAQPNGPPEAEPRPPQSPASTA----SFIFSKGSRKLQLERPV--SPE 990 AA P P E P P+ PA T + KG+ L+ P +P+ Sbjct: 670 ---KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPK 726 Query: 991 TQA--DLQRNLVAELRSISEQRP---------PQAPKK----SPKAPPPVARKPSVGV-- 1033 A +L E S + +P P PK+ +PK P P K + Sbjct: 727 KPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTL 786 Query: 1034 --PPPASPSYPRAEPLTAPPTNG 1054 P P +P P + L T G Sbjct: 787 KEPAPTTPKKPAPKELAPTTTKG 809 Score = 102 bits (253), Expect = 3e-21 Identities = 153/726 (21%), Positives = 239/726 (32%), Gaps = 82/726 (11%) Query: 403 QPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPESSTASNSVVPPPQGGSGRG 462 +P S P + T S + +T S + +P +T P+ + Sbjct: 357 EPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTT 416 Query: 463 SPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPP--PPRRTHSLHQRGLAVPDGPLG 520 + T S + + + + + K P P P T + + P Sbjct: 417 TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAP 476 Query: 521 LPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSP 580 PK P+ P P T E A P P P + P S P+ P T + Sbjct: 477 TTPKEPAPTAPKKPAPTTP--KEPAPTTPKEPAPTTTKEP------SPTTPKEPAPTTTK 528 Query: 581 SSGYSSQSGTPTLPPKGLAGPPA-SPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSD 639 S+ +++ PT P SP + P P T+ + P + ++ + Sbjct: 529 SAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP---TTPKEPAPTTPKKPAP--TTPKE 583 Query: 640 PAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPN---PAAPALAAPAVVPGP 696 PAP+ P P + P PK PAP +P + P +P P P AP P Sbjct: 584 PAPTTPKEP---APTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKP 640 Query: 697 VSTT--DASPQSP--PTPQTT-----LTPLQESPVISKDQSP--PPSPPPSYHPPPPPTK 745 TT + +P +P PTP T TP +P K+ +P P P P+ P PT Sbjct: 641 APTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT 700 Query: 746 KPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFP----------------- 788 E P TA L++P P PAP+E + P Sbjct: 701 PKETAPTTPKG--TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA 758 Query: 789 ---PPEEAFFSVASPEPAGPSGS-PELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAP 844 P E A + P P P G+ P + PA ++ A + P + P + + P Sbjct: 759 PTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP 818 Query: 845 ASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALG 904 A + P A KEP + P P T + + +P + Sbjct: 819 APTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDEST- 877 Query: 905 PSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQ 964 P +P +AL P++ AA + + + A + + PE P+ Sbjct: 878 PELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTT-TAKDKTTERDLRTTPETTTAAPK 936 Query: 965 SPASTASFIFSKGSRKLQLERP-VSPETQADLQRNLVAELRSIS---------------- 1007 TA+ K+ V+ T D + L++ + Sbjct: 937 MTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTE 996 Query: 1008 ------EQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEP-LTAPPTNGLPHTQD 1060 E P+ + KA P +KP+ P S P+ P + P T P Sbjct: 997 IMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMT 1056 Query: 1061 RTKREL 1066 T EL Sbjct: 1057 STMPEL 1062 Score = 84.7 bits (208), Expect = 4e-16 Identities = 108/479 (22%), Positives = 171/479 (35%), Gaps = 59/479 (12%) Query: 400 SSPQPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPESSTASNSVVPPPQ--G 457 ++ +P P + T + S + T +T S + +P +T P+ Sbjct: 510 TTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPA 569 Query: 458 GSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDG 517 + P+ + E + T + + + + P P+ T P Sbjct: 570 PTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET---------APTT 620 Query: 518 PLGLPPKPERKQQPQLP-RPPTTGGSEGAGAAPCPPNPANSWVPG------LSPGGSRRP 570 P L P K P P +P T E A P P P P +P + P Sbjct: 621 PKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEP 680 Query: 571 ----PRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASV 626 P+ P T ++ T PKG A P + + P P++ + Sbjct: 681 APTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA--PTTLKEPAPTTPKKPAPKELAPTTT 738 Query: 627 SSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRS------- 679 ++ C PAP+ G TP + P PK PAP +P + P + Sbjct: 739 KEPTSTTCDK---PAPTTPKGTAPTTP---KEPAPTTPKEPAPTTPKGTAPTTLKEPAPT 792 Query: 680 -PNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTT--LTPLQESPVISKDQSP--PPSPP 734 P AP AP GP STT P +P TP+ T TP + +P K +P P +PP Sbjct: 793 TPKKPAPKELAPTTTKGPTSTTSDKP-APTTPKETAPTTPKEPAPTTPKKPAPTTPETPP 851 Query: 735 P--SYHPPPPPTKKPEVVVEAP--SASETAEEPL--------QDPNWPPPPPPAPEEQDL 782 P S P TK+P + ++P S E + EP ++P P PA + ++ Sbjct: 852 PTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEM 911 Query: 783 -SMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSS---ATALQIQPPGSPDPPP 837 + A E + A P + E ++ ++ S AT Q+ + D P Sbjct: 912 TTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTP 970 >gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] Length = 1012 Score = 108 bits (271), Expect = 2e-23 Identities = 167/669 (24%), Positives = 227/669 (33%), Gaps = 144/669 (21%) Query: 414 DTWSHSQSSDTIVSDGSTLSSKGGSEGQPESSTASNSVVPPPQGGSGRGSPSGGSTAEAS 473 D S S T S GS + + G + QP S S + SGR SPS ST Sbjct: 10 DGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAAST---- 65 Query: 474 DTLSIRSSGQLSGRSV--SLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQP 531 SS +V S +K+K P +++ QR D ++ + Sbjct: 66 ------SSNDSKAETVKKSAKKVKEEASSPLKSNK-RQREKVASDTEEADRTSSKKTKTQ 118 Query: 532 QLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTP 591 ++ RP SPS G S + Sbjct: 119 EISRPN-----------------------------------------SPSEGEGESSDSR 137 Query: 592 TLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQIL 651 ++ +G + P + S S S+ S + SD SD S Q + Sbjct: 138 SVNDEGSSDPK---------------DIDQDNRSTSPSIPSPQDNESD---SDSSAQQQM 179 Query: 652 TPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSP--PT 709 + P PAP S PP P+ P P P +A AV P T +P P PT Sbjct: 180 LQAQPPALQAPTGVTPAPSSAPPGTPQLPTPG-PTPSATAVPPQGSPTASQAPNQPQAPT 238 Query: 710 PQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEV-VVEAPSASETAEEPLQDPN 768 T +Q++P + + P P PPP HP P P +P PSA A+ PL Sbjct: 239 APVPHTHIQQAPALHPQRPPSPHPPP--HPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296 Query: 769 WPPPPPPAPEE-QDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAAS--------S 819 PP P Q + P P + F P G L +SPAA+ Sbjct: 297 -----PPGPHSLQAGPLLQHPGPPQPF----GLPPQASQGQAPLGTSPAAAYPHTSLQLP 347 Query: 820 SSATALQIQPPGSPDP-PPAPPA-----PAPASSAPGHVAKLPQKEPVGCSKGGGPPRED 873 +S +ALQ Q P P PPAP A P P + P A K P S GP Sbjct: 348 ASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLS---GPSPFS 404 Query: 874 VGAPLVTPSLLQMVRLRSVGAPGGAPTPALG--------PSAPQKPLRRALSGRASPVPA 925 + A L P L+ + S P A P L PS+P +P S P PA Sbjct: 405 MNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPA 464 Query: 926 --PSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEP-------RPPQSPASTASFIFSK 976 P +GLH + P GPP P PP P ++A S Sbjct: 465 SHPPTGLHQVAPQPPFAQ------HPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSG 518 Query: 977 GSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPS-----V 1031 + + + L ++ + + P++PPP R PS V Sbjct: 519 AAA-----------SGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVV 567 Query: 1032 GVPPPASPS 1040 P AS S Sbjct: 568 DTPSHASQS 576 Score = 105 bits (263), Expect = 2e-22 Identities = 182/773 (23%), Positives = 259/773 (33%), Gaps = 148/773 (19%) Query: 370 GRCSLRTLSRCSLHSASPASVRSLGRFSSVSSPQPRS-----------RHPSSSSDTWSH 418 G+ S+RT S +++RS GR +SP R+ R+ S++ T S+ Sbjct: 14 GKHSMRTRRS----RGSMSTLRS-GRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSN 68 Query: 419 SQSSDTIVSDGSTLSSKGGSE------------GQPESSTASNSVVPPPQGGSGRGSPSG 466 ++T+ + + S E + ++S Q S SPS Sbjct: 69 DSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSE 128 Query: 467 GSTAEASDTLSIRSSGQLSGRSVSLRKLKRPP--PPPRRTHS---------LHQRGLAVP 515 G E+SD+ S+ G + + P P P+ S + Q Sbjct: 129 GE-GESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPAL 187 Query: 516 DGPLGLPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRS-- 573 P G+ P P P P+ PT G + A A P +P S P + P + Sbjct: 188 QAPTGVTPAPS-SAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHI 246 Query: 574 -------PERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASV 626 P+R SP P P G AG P++P AQPP L G Sbjct: 247 QQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPP-------LHGQGPPG 299 Query: 627 SSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPP--SKPRSPNPAA 684 SL ++GP + HP P PF PP S+ ++P + Sbjct: 300 PHSL--------------QAGPLL-----------QHPGPPQPFGLPPQASQGQAPLGTS 334 Query: 685 PALAAPAV-VPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPP 743 PA A P + P S + Q PP Q PL +P+ PPP+ P P P Sbjct: 335 PAAAYPHTSLQLPASQSALQSQQPPREQ----PLPPAPLAMPHIKPPPTTPIPQLPAPQA 390 Query: 744 TKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFP---PPEEAFFSVASP 800 K P + S A N PPPP P LS P PP + P Sbjct: 391 HKHPPHLSGPSPFSMNA-------NLPPPPALKPLSS-LSTHHPPSAHPPPLQLMPQSQP 442 Query: 801 EPAGPSGSPELVSS-----PAASSSSATALQIQP----------PGSPDP--PPAPPAPA 843 P+ P+ P L S P AS Q+ P PG P P PP P+ + Sbjct: 443 LPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTS 502 Query: 844 PASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPAL 903 + PG A+ P G + GG PL T + + L P P P Sbjct: 503 TPPAGPGTSAQPPCS---GAAASGGSIAGGSSCPLPTVQIKEEA-LDDAEEPESPPPPPR 558 Query: 904 GPSAP----QKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAE 959 PS P + S R A L LA S+ L+ + +A+ Sbjct: 559 SPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSK-LAKKREEAIEKAK 617 Query: 960 PRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSP 1019 Q K + + E+ E + + +R AE + + + P Sbjct: 618 REAEQ-----------KAREEREREKEKEKEREREREREREAERAAKASSSAHEGRLSDP 666 Query: 1020 KAPPPVARKPSVGVPPPASPSYPRAEPLTAPPTNGL--------PHTQDRTKR 1064 + P +PS PP + P P P T L PH T R Sbjct: 667 QLSGPGHMRPSFEPPPTTIAAVP---PYIGPDTPALRTLSEYARPHVMSPTNR 716 Score = 43.9 bits (102), Expect = 8e-04 Identities = 43/172 (25%), Positives = 66/172 (38%), Gaps = 26/172 (15%) Query: 927 SSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERP 986 SS ++ + +L A G++ A + PP P P +A+ + +GS + P Sbjct: 173 SSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTAS-QAP 231 Query: 987 VSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEP 1046 P+ A + QAP P+ PP PPP +P +P Sbjct: 232 NQPQ----------APTAPVPHTHIQQAPALHPQRPPSPH-------PPPHPSPHPPLQP 274 Query: 1047 LT------APPTNGLP--HTQDRTKRELAENGGVLQLVGPEEKMGLPGSDSQ 1090 LT + P++ P H Q + G +LQ GP + GLP SQ Sbjct: 275 LTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQ 326 >gi|150170670 piccolo isoform 2 [Homo sapiens] Length = 4935 Score = 108 bits (270), Expect = 3e-23 Identities = 177/783 (22%), Positives = 269/783 (34%), Gaps = 156/783 (19%) Query: 334 PAEPLSPAMSISPQA-TYLSKLIPHAVLPPTVDVV-ALGRCSLRTLSRCSLHSASPASVR 391 P P P +S S T+ S+ P T+ + + R L+ + S+ + V Sbjct: 102 PGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVN 161 Query: 392 SLGRFSSVSSPQPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPESSTASNSV 451 +L SSV + + D S S++S + + K +G+PE Sbjct: 162 ALSAVSSVVNK-------FNPFDLISDSEASQEETTKKQKVVQK--EQGKPEGIIKPPLQ 212 Query: 452 VPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPPPPRRTHSLHQRG 511 PP+ + P + SI S K+K PP G Sbjct: 213 QQPPKPIPKQQGPGRDPLQQDGTPKSISSQQP--------EKIKSQPP-----------G 253 Query: 512 LAVP-DGPLGLPPKPERKQ--QPQLPRPPTTGGS--EGAGAAPCPPNPANSWVPGLSPG- 565 P GP P K Q RP T G P P+P+ + +PG Sbjct: 254 TGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGK 313 Query: 566 -------------GSRRPPRSPERTLSPSSGYSSQSGT--PTLPPKGLAGPPASP-GKAQ 609 G +PP P P + Q GT P + P G PPA P G A+ Sbjct: 314 PPAQQPGHEKSQPGPAKPPAQPSGLTKP---LAQQPGTVKPPVQPPGTTKPPAQPLGPAK 370 Query: 610 PPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILT-PLGDRFVIPPHPKVPA 668 PP + + S+ S++ GP+ L P G V + P Sbjct: 371 PPAQQ---------------------TGSEKPSSEQPGPKALAQPPG---VGKTPAQQPG 406 Query: 669 PFSPPPSKPRSPNPAA--PALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKD 726 P PP + +P P A P L +PA PGP T P P P + Q P + Sbjct: 407 PAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKT----PVQQPGP-GKIPAQQAGPGKTSA 461 Query: 727 QSPPPSPPPSYHPPP--PPTKKPEVVVEAPSASETAEEPLQDPNWPPPPP-------PAP 777 Q P+ PPS P P PP ++P P +A+ P Q P PPP P+P Sbjct: 462 QQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSP 521 Query: 778 EEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQ--IQPPGSPDP 835 ++ + P A S P PA PS + P + + S LQ P + P Sbjct: 522 QQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQS--TKPVSQTGSGKPLQPPTVSPSAKQP 579 Query: 836 PP--APPAPAPASSAPGHVAKLPQK---------EPVGCSKGGGPPREDVGAPLVTPSLL 884 P P P + + +P+K + CS G P P L Sbjct: 580 PSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNP---------NPHLT 630 Query: 885 QMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAAS 944 ++ + ++RAL G +PVP+ +LK + + Sbjct: 631 EVKEWLCLNC----------------QMKRALGGDLAPVPSSPQ-----PKLKTAPVTTT 669 Query: 945 EGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADL-QRNLVAEL 1003 +S + P P + P+ +P K L + P+ L ++ + Sbjct: 670 SAVSKSSPQ-PQQTSPKKDAAP-------------KQDLSKAPEPKKPPPLVKQPTLHGS 715 Query: 1004 RSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEPLTAPPTNGLPHTQDRTK 1063 S ++PP+A S APP PS P + P+ + P T+ + + TK Sbjct: 716 PSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTK 775 Query: 1064 REL 1066 ++ Sbjct: 776 PDI 778 Score = 106 bits (264), Expect = 1e-22 Identities = 171/679 (25%), Positives = 235/679 (34%), Gaps = 134/679 (19%) Query: 429 GSTLSSKGGSEGQPESSTASNSVVPPPQGGSGRGSPS-----GGSTAEASDTLSIRSSGQ 483 G+ S +G EG PE A+ + G SG GSPS G A+ S LS Q Sbjct: 2 GNEASLEG--EGLPEGLAAAAAA---GGGASGAGSPSHTAIPAGMEADLSQ-LSEEERRQ 55 Query: 484 LSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGSE 543 ++ + L + PP S P RKQ+ PP G Sbjct: 56 IAAVMSRAQGLPKGSVPPAAAES----------------PSMHRKQELDSSHPPKQSGR- 98 Query: 544 GAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPA 603 PP+P PGLS + RS ++ LP + + Sbjct: 99 -------PPDPGRPAQPGLSKSRTTDTFRSEQK----------------LPGRSPSTISL 135 Query: 604 SPGKAQPPKPERVTSLRSPG-ASVSSSLTSLCSSSSDPAP----SDRSGPQILTPLGDRF 658 K++ E S PG S ++L+++ S + P SD Q T + Sbjct: 136 KESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKV 195 Query: 659 VIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQ 718 V K P PP + + P P P P P D +P+S + Q Q Sbjct: 196 VQKEQGK-PEGIIKPPLQQQPPKP-IPKQQGPGRDP---LQQDGTPKSISSQQPEKIKSQ 250 Query: 719 ESPVISKDQSPPPSPPPSYHPPP-------PPTKKPEVVVEAPSASETAEEPLQDPNWPP 771 Q P +P + P P TK+ ++V E+ + L P+ PP Sbjct: 251 PPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIV-----RGESVKPSLPSPSKPP 305 Query: 772 PPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPG 831 P P + PP ++ + P PA P P ++ P A +QPPG Sbjct: 306 IQQPTPGK--------PPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPG 357 Query: 832 SPDPPPAPPAPA-----------PASSAPG--------HVAKLPQKEPVGCSKGGGPPRE 872 + PP P PA P+S PG V K P ++P G +K PP + Sbjct: 358 TTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQP-GPAK---PPTQ 413 Query: 873 DVGAPLVTPSLLQMVRLRS-VGAPGGAPTPALGPSAPQKPLRRALSGRAS---------- 921 VG P L Q L+S APG TP P + P ++A G+ S Sbjct: 414 QVGTP---KPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPP 470 Query: 922 ---PVPAPSSGLHAAVRLKACSLAASEGLSSAQPNG--PPEAEPRP----PQSPASTASF 972 P PA S S QP PP +P P PQ P ST Sbjct: 471 SQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPP 530 Query: 973 IFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVG 1032 GS K ++P + A V++ S +P Q P SP A P PS G Sbjct: 531 SQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGS---GKPLQPPTVSPSAKQP----PSQG 583 Query: 1033 VPPPASPSYPRAEPLTAPP 1051 +P P E L P Sbjct: 584 LPKTICPLCNTTELLLHVP 602 Score = 99.0 bits (245), Expect = 2e-20 Identities = 236/1056 (22%), Positives = 363/1056 (34%), Gaps = 211/1056 (19%) Query: 112 SGRPPHLEELHTQAQEGLRSLQ----HQEKQKLNKGGWDHGDTQSIQSSRTGPDEDNISF 167 SGRPP + AQ GL + + +QKL T S++ S++ D Sbjct: 96 SGRPP---DPGRPAQPGLSKSRTTDTFRSEQKLPGRS---PSTISLKESKSRTDLKEEHK 149 Query: 168 CSQTTSYVAESSTAEDALSIRSEMIQRKGSTFRPHDSFPKSGKSGRRRRERRSTVL---- 223 S +++E + ALS S ++ + F P D S S +++ V Sbjct: 150 SSMMPGFLSEVN----ALSAVSSVVNK----FNPFDLISDSEASQEETTKKQKVVQKEQG 201 Query: 224 ---GL---------PQHVQKELGL-RNEREAPGTPRAPGARDAVRIPTVDGRPRGTSGMG 270 G+ P+ + K+ G R+ + GTP++ ++ +I + +P GT G Sbjct: 202 KPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKS---QPPGT-GKP 257 Query: 271 ARVSLQALEAEAEAGAETEAMLQRHIDR--VYRDDTFVGRSTGTRAP-PLTRPMSLAVPG 327 + Q + + + LQR R + D G S P P P+ PG Sbjct: 258 IQGPTQTPQTD-----HAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPG 312 Query: 328 LTGGAGPAEPLSPAMSISPQATYLSKLIPHAVLPPTVDVVALGRCSLRTLSRCSLHSASP 387 P S P A P A P TV + + ++ L A P Sbjct: 313 KPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQ-PLGPAKP 371 Query: 388 ASVRSLGRFSSVSSPQPRS-RHPSSSSDTWSH----SQSSDTIVSDGSTLSSKGGSEGQP 442 + ++ S P P++ P T + ++ V L+ + G + Sbjct: 372 PAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPA 431 Query: 443 ESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPPPPR 502 ++ + + V P G +G A T + QL G + +PPP Sbjct: 432 KAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPA-------KPPP--- 481 Query: 503 RTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGL 562 Q G A P KP QQP +PP + A P P P ++ P Sbjct: 482 -----QQPGPAKPPPQQPGSAKPP-SQQPGSTKPPP---QQPGPAKPSPQQPGSTKPPSQ 532 Query: 563 SPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPK---PERVTSL 619 PG ++ + P PS+ S++ + T K L P SP QPP P+ + L Sbjct: 533 QPGSAKPSAQQPSPA-KPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPL 591 Query: 620 RSPG---------------ASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHP 664 + +++ SLC + +P LT + + + Sbjct: 592 CNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPH---------LTEVKEWLCLNCQM 642 Query: 665 K--VPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPV 722 K + +P PS P+ P + PV+TT A +S P PQ T +P Sbjct: 643 KRALGGDLAPVPSSPQ-----------PKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPK 691 Query: 723 ISKDQSPPPSPPP---------------SYHPP-------PPPTKKPEVVVEAPSASETA 760 ++P P PP + PP P P K+P V E A Sbjct: 692 QDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVAD 751 Query: 761 EEPLQDPNWPPPP-----------PPAPEEQDLSMAD-----------------FPPPEE 792 ++P Q P P P + S A+ FPP E Sbjct: 752 DKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGE 811 Query: 793 A---FFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAP 849 F S A P PA S +++S P SS S Q+ P + P A +P Sbjct: 812 KVSPFDSKAIPRPASDS---KIISHPGPSSESKGQKQVDPVQKKE----EPKKAQTKMSP 864 Query: 850 GHVAKLPQKEPVGCSKGGGP---PREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPS 906 AK P G GP + V P +P + R S+ P P+ Sbjct: 865 KPDAK---PMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPT 921 Query: 907 APQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEG-LSSAQPNGPPEAEPRPPQS 965 PQ+ + L G + + + +S L S A G S + P P + P P Q Sbjct: 922 TPQETVTGKLFGFGASIFSQASNL--------ISTAGQPGPHSQSGPGAPMKQAPAPSQP 973 Query: 966 PASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKA--PP 1023 P S+G K + P +P +++ E + P A K PKA P Sbjct: 974 PT-------SQGPPKSTGQAPPAPAKSIPVKK----------ETKAPAAEKLEPKAEQAP 1016 Query: 1024 PVARKPSVGVPPPASPSYPRAEPLTAPPTNGLPHTQ 1059 V R + PPP S + LTA P + T+ Sbjct: 1017 TVKRTETEKKPPPIKDS----KSLTAEPQKAVLPTK 1048 Score = 56.2 bits (134), Expect = 2e-07 Identities = 92/356 (25%), Positives = 121/356 (33%), Gaps = 46/356 (12%) Query: 622 PGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPN 681 P + + S S+ S + P P RS D PP P P P PPP P P Sbjct: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSL------DISAQPPPPPPPPPPPPPPPPPPPPP 2425 Query: 682 PAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPP 741 P P + + T ASP + TP E+ + + P + + PPP Sbjct: 2426 PLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPP 2485 Query: 742 PPTKKPEVVVEAPSASETAEEPLQDPNWPP--PPPPAPEEQDLSM--ADFPPPEEAFFSV 797 P K + PS P +P+ PP P P P+ + D P Sbjct: 2486 VPPKPSSI----PSGLVFTHRP--EPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLT 2539 Query: 798 AS-------------PEPAGPSGSPELVSSPAASSS-SATALQIQPPGSPDPPPAPPAPA 843 +S P P P SSP S S + T + I P P P A Sbjct: 2540 SSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQ 2599 Query: 844 PASSAP-GHVAK-LPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTP 901 +S P G +K L EPV PP V P+ + + S + TP Sbjct: 2600 AITSWPLGSPSKDLVSVEPVFSVV---PPVTAVEIPISSEQTFYI----SGALQTFSATP 2652 Query: 902 ALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPE 957 PS+ Q + V S +A R S A S GLSS PPE Sbjct: 2653 VTAPSSFQAAPTSVTQFLTTEV---SKTEVSATR----STAPSVGLSSISITIPPE 2701 Score = 55.1 bits (131), Expect = 4e-07 Identities = 161/764 (21%), Positives = 236/764 (30%), Gaps = 156/764 (20%) Query: 381 SLHSASPASVRSLGRFSSVSSPQPRSRHPSSSSDTWSHSQSSDT-----IVSDGSTLSSK 435 +LH + A + S+S P P + PS S+ + D +V + L S Sbjct: 711 TLHGSPSAKAKQPPEADSLSKPAP-PKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSS 769 Query: 436 GGSEGQPE------SSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSV 489 + +P+ S A PP + S + S S T E ++ R Sbjct: 770 SSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIP----RPA 825 Query: 490 SLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAGAAP 549 S K+ P P S +G D P+ +P++ Q P+P +G+ P Sbjct: 826 SDSKIISHPGP-----SSESKGQKQVD-PVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPP 879 Query: 550 CPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQ 609 P A VP +P S +P R +S G+ T PK +Q Sbjct: 880 GPRPTAGQTVP--TPQQSPKPQEQSRR-------FSLNLGSITDAPK-----------SQ 919 Query: 610 PPKPERVTS--LRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPH---- 663 P P+ + L GAS+ S ++L S++ P P +SGP PP Sbjct: 920 PTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGP 979 Query: 664 PKV-----PAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPT--------- 709 PK PAP P K + PAA L A V T+ + PP Sbjct: 980 PKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAE 1039 Query: 710 PQTTLTP--LQESPVISKDQSPPP----------SPPPSYH----------------PPP 741 PQ + P L++SP K +S P PP+++ P P Sbjct: 1040 PQKAVLPTKLEKSP---KPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTP 1096 Query: 742 PPTKKPEVVVEAPSASETAEEPLQDPNWPPPPP--------PAPEEQDLSMADFPPP--- 790 T+ E + L D PP P P P E PP Sbjct: 1097 HLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKL 1156 Query: 791 -----------EEAFFSVASPEPAGPSGSPELVSSPAASSSS------ATALQIQPPGSP 833 E E P +V++ S A+ALQ + P Sbjct: 1157 VKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPE 1216 Query: 834 DPPPAP------------------PAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVG 875 + P P P P P+++ K E+ Sbjct: 1217 EKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKL 1276 Query: 876 APLVTPSLLQ---MVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHA 932 V P +Q + + G P G TP P K + P A + Sbjct: 1277 EGRVAPKTVQEGKQPQTKMEGLPSG--TPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEP 1334 Query: 933 AVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASF------------IFSKGSRK 980 S+ SS QP P S ++S KG +K Sbjct: 1335 GKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKK 1394 Query: 981 LQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPP 1024 + SP + +DL + L + Q A +KS K P Sbjct: 1395 DSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQP 1438 Score = 50.4 bits (119), Expect = 9e-06 Identities = 127/529 (24%), Positives = 182/529 (34%), Gaps = 110/529 (20%) Query: 595 PKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPL 654 P+GLA A+ G A T++ A + + L+ L + S Q L P Sbjct: 13 PEGLAAAAAAGGGASGAGSPSHTAIP---AGMEADLSQLSEEERRQIAAVMSRAQGL-PK 68 Query: 655 GDRFVIPP--------HPKVPAPFSPPPSKP-RSPNPAAPALAAPAVVPGPVSTTDASPQ 705 G +PP H K S PP + R P+P PA P + + T S Q Sbjct: 69 GS---VPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPA--QPGLSKSRTTDTFRSEQ 123 Query: 706 SPP--TPQTTLTPLQESPVISKDQSPPPSPPP----------------SYHP-------- 739 P +P T +S K++ P ++P Sbjct: 124 KLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSE 183 Query: 740 --PPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSV 797 TKK +VV + E +P P PP P P++Q Sbjct: 184 ASQEETTKKQKVVQKEQGKPEGIIKP---PLQQQPPKPIPKQQG---------------- 224 Query: 798 ASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDP---PPAPPAPAPASSAPGHVAK 854 +P G+P+ +SS ++ QPPG+ P P P A A Sbjct: 225 PGRDPLQQDGTPKSISSQQPEK-----IKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDAS 279 Query: 855 LPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRR 914 PQ + +G E V L +PS P PTP P A Q + Sbjct: 280 RPQTKQADIVRG-----ESVKPSLPSPSK----------PPIQQPTPGK-PPAQQPGHEK 323 Query: 915 ALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIF 974 + G A P PA SGL LA G + +P P +PP P A Sbjct: 324 SQPGPAKP-PAQPSGLTKP-------LAQQPG--TVKPPVQPPGTTKPPAQPLGPAKPPA 373 Query: 975 SK-GSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVGV 1033 + GS K E+P P+ A Q V + + + P + P + P P+A++P G+ Sbjct: 374 QQTGSEKPSSEQP-GPKALA--QPPGVGKTPA-QQPGPAKPPTQQVGTPKPLAQQP--GL 427 Query: 1034 PPPASPSYPRAEPLTAPPTNGLPHTQDRTKRELAENGGVL----QLVGP 1078 PA P P+ P +P Q + A+ G QL GP Sbjct: 428 QSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGP 476 Score = 45.4 bits (106), Expect = 3e-04 Identities = 72/313 (23%), Positives = 103/313 (32%), Gaps = 44/313 (14%) Query: 757 SETAEEPLQDPNWPPPPPPA---PEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVS 813 +E + L + + PP P ++ LS F E F P PSGSP + S Sbjct: 2328 AERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGET--FGQEKPASQLPSGSPSVSS 2385 Query: 814 SPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLP------------QKEPV 861 PA + + P PPP PP P P P LP +K V Sbjct: 2386 LPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTV 2445 Query: 862 GCSKGGGPPREDVGAPLVTPSLLQ-----MVRLRSVGAPGGAPTPALGPSA--------P 908 P D L T ++L+ + R+ + P P P+ PS P Sbjct: 2446 ASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEP 2505 Query: 909 QKP---LRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQS 965 KP + + + P+ L S ++SA P P P S Sbjct: 2506 SKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHS 2565 Query: 966 PASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPV 1025 S+ F S + + P P T D S + Q P SP + V Sbjct: 2566 NKSSPRFSKSLTETYVVITLPSEPGTPTD----------SSASQAITSWPLGSP-SKDLV 2614 Query: 1026 ARKPSVGVPPPAS 1038 + +P V PP + Sbjct: 2615 SVEPVFSVVPPVT 2627 Score = 42.4 bits (98), Expect = 0.002 Identities = 81/355 (22%), Positives = 123/355 (34%), Gaps = 83/355 (23%) Query: 479 RSSGQLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPT 538 + + QL S S+ L P P R+ SL P P PP P P P PP Sbjct: 2371 KPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPP 2430 Query: 539 TGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQ---------SG 589 T +P P + SP + P TL ++ S + Sbjct: 2431 T--------SPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTA 2482 Query: 590 TPTLPPKGLAGP----------PASPGKA-QPPKPERVTSLRSP--------GASVSSSL 630 P +PPK + P P+ P A +P P+ T+ + P G S++SS+ Sbjct: 2483 PPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSM 2542 Query: 631 TSLCSSSSD---PAP-------SDRSGPQILTPLGDRFVI---PPHPKVPA--------- 668 T +S+D P+P S++S P+ L + +V+ P P P Sbjct: 2543 TLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAIT 2602 Query: 669 --PFSPPPSKPRSPNP---AAPALAAPAV---------VPGPVSTTDASPQSPPT----P 710 P P S P P + A + + G + T A+P + P+ Sbjct: 2603 SWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAPSSFQAA 2662 Query: 711 QTTLTPLQESPVISKDQSPPPSPPP-------SYHPPPPPTKKPEVVVEAPSASE 758 T++T + V + S S P S PP P + +E P E Sbjct: 2663 PTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPPEPLALDNIHLEKPQYKE 2717 Score = 34.3 bits (77), Expect = 0.66 Identities = 35/165 (21%), Positives = 56/165 (33%), Gaps = 21/165 (12%) Query: 673 PPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPS 732 PP + P P ++ V + P+SP + ++PL + P Sbjct: 3586 PPKDKKRPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKALESAFVPYEK 3645 Query: 733 PPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEE 792 P P P P++ P++ +TA+ + + P P +P + S A F Sbjct: 3646 PLPD-DISPQKVLHPDMAKVPPASPKTAK--MMQRSMSDPKPLSPTADESSRAPF----- 3697 Query: 793 AFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPP 837 E GS + SS A T P+PPP Sbjct: 3698 -----QYTEGYTTKGSQTMTSSGAQKKVKRTL--------PNPPP 3729 Score = 32.3 bits (72), Expect = 2.5 Identities = 13/30 (43%), Positives = 15/30 (50%) Query: 1010 RPPQAPKKSPKAPPPVARKPSVGVPPPASP 1039 +PP P P PPP P +PPP SP Sbjct: 2404 QPPPPPPPPPPPPPPPPPPPPPPLPPPTSP 2433 Score = 30.8 bits (68), Expect = 7.3 Identities = 20/51 (39%), Positives = 21/51 (41%), Gaps = 12/51 (23%) Query: 1006 ISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEPLTAPPTNGLP 1056 IS Q PP P P PPP PPP P P P T+P LP Sbjct: 2401 ISAQPPPPPP---PPPPPP---------PPPPPPPPPPLPPPTSPKPTILP 2439 >gi|150378539 piccolo isoform 1 [Homo sapiens] Length = 5142 Score = 108 bits (270), Expect = 3e-23 Identities = 177/783 (22%), Positives = 269/783 (34%), Gaps = 156/783 (19%) Query: 334 PAEPLSPAMSISPQA-TYLSKLIPHAVLPPTVDVV-ALGRCSLRTLSRCSLHSASPASVR 391 P P P +S S T+ S+ P T+ + + R L+ + S+ + V Sbjct: 102 PGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVN 161 Query: 392 SLGRFSSVSSPQPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPESSTASNSV 451 +L SSV + + D S S++S + + K +G+PE Sbjct: 162 ALSAVSSVVNK-------FNPFDLISDSEASQEETTKKQKVVQK--EQGKPEGIIKPPLQ 212 Query: 452 VPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPPPPRRTHSLHQRG 511 PP+ + P + SI S K+K PP G Sbjct: 213 QQPPKPIPKQQGPGRDPLQQDGTPKSISSQQP--------EKIKSQPP-----------G 253 Query: 512 LAVP-DGPLGLPPKPERKQ--QPQLPRPPTTGGS--EGAGAAPCPPNPANSWVPGLSPG- 565 P GP P K Q RP T G P P+P+ + +PG Sbjct: 254 TGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGK 313 Query: 566 -------------GSRRPPRSPERTLSPSSGYSSQSGT--PTLPPKGLAGPPASP-GKAQ 609 G +PP P P + Q GT P + P G PPA P G A+ Sbjct: 314 PPAQQPGHEKSQPGPAKPPAQPSGLTKP---LAQQPGTVKPPVQPPGTTKPPAQPLGPAK 370 Query: 610 PPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILT-PLGDRFVIPPHPKVPA 668 PP + + S+ S++ GP+ L P G V + P Sbjct: 371 PPAQQ---------------------TGSEKPSSEQPGPKALAQPPG---VGKTPAQQPG 406 Query: 669 PFSPPPSKPRSPNPAA--PALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKD 726 P PP + +P P A P L +PA PGP T P P P + Q P + Sbjct: 407 PAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKT----PVQQPGP-GKIPAQQAGPGKTSA 461 Query: 727 QSPPPSPPPSYHPPP--PPTKKPEVVVEAPSASETAEEPLQDPNWPPPPP-------PAP 777 Q P+ PPS P P PP ++P P +A+ P Q P PPP P+P Sbjct: 462 QQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSP 521 Query: 778 EEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQ--IQPPGSPDP 835 ++ + P A S P PA PS + P + + S LQ P + P Sbjct: 522 QQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQS--TKPVSQTGSGKPLQPPTVSPSAKQP 579 Query: 836 PP--APPAPAPASSAPGHVAKLPQK---------EPVGCSKGGGPPREDVGAPLVTPSLL 884 P P P + + +P+K + CS G P P L Sbjct: 580 PSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNP---------NPHLT 630 Query: 885 QMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAAS 944 ++ + ++RAL G +PVP+ +LK + + Sbjct: 631 EVKEWLCLNC----------------QMKRALGGDLAPVPSSPQ-----PKLKTAPVTTT 669 Query: 945 EGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADL-QRNLVAEL 1003 +S + P P + P+ +P K L + P+ L ++ + Sbjct: 670 SAVSKSSPQ-PQQTSPKKDAAP-------------KQDLSKAPEPKKPPPLVKQPTLHGS 715 Query: 1004 RSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEPLTAPPTNGLPHTQDRTK 1063 S ++PP+A S APP PS P + P+ + P T+ + + TK Sbjct: 716 PSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTK 775 Query: 1064 REL 1066 ++ Sbjct: 776 PDI 778 Score = 106 bits (264), Expect = 1e-22 Identities = 171/679 (25%), Positives = 235/679 (34%), Gaps = 134/679 (19%) Query: 429 GSTLSSKGGSEGQPESSTASNSVVPPPQGGSGRGSPS-----GGSTAEASDTLSIRSSGQ 483 G+ S +G EG PE A+ + G SG GSPS G A+ S LS Q Sbjct: 2 GNEASLEG--EGLPEGLAAAAAA---GGGASGAGSPSHTAIPAGMEADLSQ-LSEEERRQ 55 Query: 484 LSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGSE 543 ++ + L + PP S P RKQ+ PP G Sbjct: 56 IAAVMSRAQGLPKGSVPPAAAES----------------PSMHRKQELDSSHPPKQSGR- 98 Query: 544 GAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPA 603 PP+P PGLS + RS ++ LP + + Sbjct: 99 -------PPDPGRPAQPGLSKSRTTDTFRSEQK----------------LPGRSPSTISL 135 Query: 604 SPGKAQPPKPERVTSLRSPG-ASVSSSLTSLCSSSSDPAP----SDRSGPQILTPLGDRF 658 K++ E S PG S ++L+++ S + P SD Q T + Sbjct: 136 KESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKV 195 Query: 659 VIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQ 718 V K P PP + + P P P P P D +P+S + Q Q Sbjct: 196 VQKEQGK-PEGIIKPPLQQQPPKP-IPKQQGPGRDP---LQQDGTPKSISSQQPEKIKSQ 250 Query: 719 ESPVISKDQSPPPSPPPSYHPPP-------PPTKKPEVVVEAPSASETAEEPLQDPNWPP 771 Q P +P + P P TK+ ++V E+ + L P+ PP Sbjct: 251 PPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIV-----RGESVKPSLPSPSKPP 305 Query: 772 PPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPG 831 P P + PP ++ + P PA P P ++ P A +QPPG Sbjct: 306 IQQPTPGK--------PPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPG 357 Query: 832 SPDPPPAPPAPA-----------PASSAPG--------HVAKLPQKEPVGCSKGGGPPRE 872 + PP P PA P+S PG V K P ++P G +K PP + Sbjct: 358 TTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQP-GPAK---PPTQ 413 Query: 873 DVGAPLVTPSLLQMVRLRS-VGAPGGAPTPALGPSAPQKPLRRALSGRAS---------- 921 VG P L Q L+S APG TP P + P ++A G+ S Sbjct: 414 QVGTP---KPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPP 470 Query: 922 ---PVPAPSSGLHAAVRLKACSLAASEGLSSAQPNG--PPEAEPRP----PQSPASTASF 972 P PA S S QP PP +P P PQ P ST Sbjct: 471 SQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPP 530 Query: 973 IFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVG 1032 GS K ++P + A V++ S +P Q P SP A P PS G Sbjct: 531 SQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGS---GKPLQPPTVSPSAKQP----PSQG 583 Query: 1033 VPPPASPSYPRAEPLTAPP 1051 +P P E L P Sbjct: 584 LPKTICPLCNTTELLLHVP 602 Score = 99.0 bits (245), Expect = 2e-20 Identities = 236/1056 (22%), Positives = 363/1056 (34%), Gaps = 211/1056 (19%) Query: 112 SGRPPHLEELHTQAQEGLRSLQ----HQEKQKLNKGGWDHGDTQSIQSSRTGPDEDNISF 167 SGRPP + AQ GL + + +QKL T S++ S++ D Sbjct: 96 SGRPP---DPGRPAQPGLSKSRTTDTFRSEQKLPGRS---PSTISLKESKSRTDLKEEHK 149 Query: 168 CSQTTSYVAESSTAEDALSIRSEMIQRKGSTFRPHDSFPKSGKSGRRRRERRSTVL---- 223 S +++E + ALS S ++ + F P D S S +++ V Sbjct: 150 SSMMPGFLSEVN----ALSAVSSVVNK----FNPFDLISDSEASQEETTKKQKVVQKEQG 201 Query: 224 ---GL---------PQHVQKELGL-RNEREAPGTPRAPGARDAVRIPTVDGRPRGTSGMG 270 G+ P+ + K+ G R+ + GTP++ ++ +I + +P GT G Sbjct: 202 KPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKS---QPPGT-GKP 257 Query: 271 ARVSLQALEAEAEAGAETEAMLQRHIDR--VYRDDTFVGRSTGTRAP-PLTRPMSLAVPG 327 + Q + + + LQR R + D G S P P P+ PG Sbjct: 258 IQGPTQTPQTD-----HAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPG 312 Query: 328 LTGGAGPAEPLSPAMSISPQATYLSKLIPHAVLPPTVDVVALGRCSLRTLSRCSLHSASP 387 P S P A P A P TV + + ++ L A P Sbjct: 313 KPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQ-PLGPAKP 371 Query: 388 ASVRSLGRFSSVSSPQPRS-RHPSSSSDTWSH----SQSSDTIVSDGSTLSSKGGSEGQP 442 + ++ S P P++ P T + ++ V L+ + G + Sbjct: 372 PAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPA 431 Query: 443 ESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPPPPR 502 ++ + + V P G +G A T + QL G + +PPP Sbjct: 432 KAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPA-------KPPP--- 481 Query: 503 RTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGL 562 Q G A P KP QQP +PP + A P P P ++ P Sbjct: 482 -----QQPGPAKPPPQQPGSAKPP-SQQPGSTKPPP---QQPGPAKPSPQQPGSTKPPSQ 532 Query: 563 SPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPK---PERVTSL 619 PG ++ + P PS+ S++ + T K L P SP QPP P+ + L Sbjct: 533 QPGSAKPSAQQPSPA-KPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPL 591 Query: 620 RSPG---------------ASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHP 664 + +++ SLC + +P LT + + + Sbjct: 592 CNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPH---------LTEVKEWLCLNCQM 642 Query: 665 K--VPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPV 722 K + +P PS P+ P + PV+TT A +S P PQ T +P Sbjct: 643 KRALGGDLAPVPSSPQ-----------PKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPK 691 Query: 723 ISKDQSPPPSPPP---------------SYHPP-------PPPTKKPEVVVEAPSASETA 760 ++P P PP + PP P P K+P V E A Sbjct: 692 QDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVAD 751 Query: 761 EEPLQDPNWPPPP-----------PPAPEEQDLSMAD-----------------FPPPEE 792 ++P Q P P P + S A+ FPP E Sbjct: 752 DKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGE 811 Query: 793 A---FFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAP 849 F S A P PA S +++S P SS S Q+ P + P A +P Sbjct: 812 KVSPFDSKAIPRPASDS---KIISHPGPSSESKGQKQVDPVQKKE----EPKKAQTKMSP 864 Query: 850 GHVAKLPQKEPVGCSKGGGP---PREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPS 906 AK P G GP + V P +P + R S+ P P+ Sbjct: 865 KPDAK---PMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPT 921 Query: 907 APQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEG-LSSAQPNGPPEAEPRPPQS 965 PQ+ + L G + + + +S L S A G S + P P + P P Q Sbjct: 922 TPQETVTGKLFGFGASIFSQASNL--------ISTAGQPGPHSQSGPGAPMKQAPAPSQP 973 Query: 966 PASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKA--PP 1023 P S+G K + P +P +++ E + P A K PKA P Sbjct: 974 PT-------SQGPPKSTGQAPPAPAKSIPVKK----------ETKAPAAEKLEPKAEQAP 1016 Query: 1024 PVARKPSVGVPPPASPSYPRAEPLTAPPTNGLPHTQ 1059 V R + PPP S + LTA P + T+ Sbjct: 1017 TVKRTETEKKPPPIKDS----KSLTAEPQKAVLPTK 1048 Score = 56.2 bits (134), Expect = 2e-07 Identities = 92/356 (25%), Positives = 121/356 (33%), Gaps = 46/356 (12%) Query: 622 PGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPN 681 P + + S S+ S + P P RS D PP P P P PPP P P Sbjct: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSL------DISAQPPPPPPPPPPPPPPPPPPPPP 2425 Query: 682 PAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPP 741 P P + + T ASP + TP E+ + + P + + PPP Sbjct: 2426 PLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPP 2485 Query: 742 PPTKKPEVVVEAPSASETAEEPLQDPNWPP--PPPPAPEEQDLSM--ADFPPPEEAFFSV 797 P K + PS P +P+ PP P P P+ + D P Sbjct: 2486 VPPKPSSI----PSGLVFTHRP--EPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLT 2539 Query: 798 AS-------------PEPAGPSGSPELVSSPAASSS-SATALQIQPPGSPDPPPAPPAPA 843 +S P P P SSP S S + T + I P P P A Sbjct: 2540 SSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQ 2599 Query: 844 PASSAP-GHVAK-LPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTP 901 +S P G +K L EPV PP V P+ + + S + TP Sbjct: 2600 AITSWPLGSPSKDLVSVEPVFSVV---PPVTAVEIPISSEQTFYI----SGALQTFSATP 2652 Query: 902 ALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPE 957 PS+ Q + V S +A R S A S GLSS PPE Sbjct: 2653 VTAPSSFQAAPTSVTQFLTTEV---SKTEVSATR----STAPSVGLSSISITIPPE 2701 Score = 55.1 bits (131), Expect = 4e-07 Identities = 161/764 (21%), Positives = 236/764 (30%), Gaps = 156/764 (20%) Query: 381 SLHSASPASVRSLGRFSSVSSPQPRSRHPSSSSDTWSHSQSSDT-----IVSDGSTLSSK 435 +LH + A + S+S P P + PS S+ + D +V + L S Sbjct: 711 TLHGSPSAKAKQPPEADSLSKPAP-PKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSS 769 Query: 436 GGSEGQPE------SSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSV 489 + +P+ S A PP + S + S S T E ++ R Sbjct: 770 SSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIP----RPA 825 Query: 490 SLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAGAAP 549 S K+ P P S +G D P+ +P++ Q P+P +G+ P Sbjct: 826 SDSKIISHPGP-----SSESKGQKQVD-PVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPP 879 Query: 550 CPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQ 609 P A VP +P S +P R +S G+ T PK +Q Sbjct: 880 GPRPTAGQTVP--TPQQSPKPQEQSRR-------FSLNLGSITDAPK-----------SQ 919 Query: 610 PPKPERVTS--LRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPH---- 663 P P+ + L GAS+ S ++L S++ P P +SGP PP Sbjct: 920 PTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGP 979 Query: 664 PKV-----PAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPT--------- 709 PK PAP P K + PAA L A V T+ + PP Sbjct: 980 PKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAE 1039 Query: 710 PQTTLTP--LQESPVISKDQSPPP----------SPPPSYH----------------PPP 741 PQ + P L++SP K +S P PP+++ P P Sbjct: 1040 PQKAVLPTKLEKSP---KPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTP 1096 Query: 742 PPTKKPEVVVEAPSASETAEEPLQDPNWPPPPP--------PAPEEQDLSMADFPPP--- 790 T+ E + L D PP P P P E PP Sbjct: 1097 HLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKL 1156 Query: 791 -----------EEAFFSVASPEPAGPSGSPELVSSPAASSSS------ATALQIQPPGSP 833 E E P +V++ S A+ALQ + P Sbjct: 1157 VKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPE 1216 Query: 834 DPPPAP------------------PAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVG 875 + P P P P P+++ K E+ Sbjct: 1217 EKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKL 1276 Query: 876 APLVTPSLLQ---MVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHA 932 V P +Q + + G P G TP P K + P A + Sbjct: 1277 EGRVAPKTVQEGKQPQTKMEGLPSG--TPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEP 1334 Query: 933 AVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASF------------IFSKGSRK 980 S+ SS QP P S ++S KG +K Sbjct: 1335 GKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKK 1394 Query: 981 LQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPP 1024 + SP + +DL + L + Q A +KS K P Sbjct: 1395 DSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQP 1438 Score = 50.4 bits (119), Expect = 9e-06 Identities = 127/529 (24%), Positives = 182/529 (34%), Gaps = 110/529 (20%) Query: 595 PKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPL 654 P+GLA A+ G A T++ A + + L+ L + S Q L P Sbjct: 13 PEGLAAAAAAGGGASGAGSPSHTAIP---AGMEADLSQLSEEERRQIAAVMSRAQGL-PK 68 Query: 655 GDRFVIPP--------HPKVPAPFSPPPSKP-RSPNPAAPALAAPAVVPGPVSTTDASPQ 705 G +PP H K S PP + R P+P PA P + + T S Q Sbjct: 69 GS---VPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPA--QPGLSKSRTTDTFRSEQ 123 Query: 706 SPP--TPQTTLTPLQESPVISKDQSPPPSPPP----------------SYHP-------- 739 P +P T +S K++ P ++P Sbjct: 124 KLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSE 183 Query: 740 --PPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSV 797 TKK +VV + E +P P PP P P++Q Sbjct: 184 ASQEETTKKQKVVQKEQGKPEGIIKP---PLQQQPPKPIPKQQG---------------- 224 Query: 798 ASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDP---PPAPPAPAPASSAPGHVAK 854 +P G+P+ +SS ++ QPPG+ P P P A A Sbjct: 225 PGRDPLQQDGTPKSISSQQPEK-----IKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDAS 279 Query: 855 LPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRR 914 PQ + +G E V L +PS P PTP P A Q + Sbjct: 280 RPQTKQADIVRG-----ESVKPSLPSPSK----------PPIQQPTPGK-PPAQQPGHEK 323 Query: 915 ALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIF 974 + G A P PA SGL LA G + +P P +PP P A Sbjct: 324 SQPGPAKP-PAQPSGLTKP-------LAQQPG--TVKPPVQPPGTTKPPAQPLGPAKPPA 373 Query: 975 SK-GSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVGV 1033 + GS K E+P P+ A Q V + + + P + P + P P+A++P G+ Sbjct: 374 QQTGSEKPSSEQP-GPKALA--QPPGVGKTPA-QQPGPAKPPTQQVGTPKPLAQQP--GL 427 Query: 1034 PPPASPSYPRAEPLTAPPTNGLPHTQDRTKRELAENGGVL----QLVGP 1078 PA P P+ P +P Q + A+ G QL GP Sbjct: 428 QSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGP 476 Score = 45.4 bits (106), Expect = 3e-04 Identities = 72/313 (23%), Positives = 103/313 (32%), Gaps = 44/313 (14%) Query: 757 SETAEEPLQDPNWPPPPPPA---PEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVS 813 +E + L + + PP P ++ LS F E F P PSGSP + S Sbjct: 2328 AERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGET--FGQEKPASQLPSGSPSVSS 2385 Query: 814 SPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLP------------QKEPV 861 PA + + P PPP PP P P P LP +K V Sbjct: 2386 LPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTV 2445 Query: 862 GCSKGGGPPREDVGAPLVTPSLLQ-----MVRLRSVGAPGGAPTPALGPSA--------P 908 P D L T ++L+ + R+ + P P P+ PS P Sbjct: 2446 ASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEP 2505 Query: 909 QKP---LRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQS 965 KP + + + P+ L S ++SA P P P S Sbjct: 2506 SKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHS 2565 Query: 966 PASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPV 1025 S+ F S + + P P T D S + Q P SP + V Sbjct: 2566 NKSSPRFSKSLTETYVVITLPSEPGTPTD----------SSASQAITSWPLGSP-SKDLV 2614 Query: 1026 ARKPSVGVPPPAS 1038 + +P V PP + Sbjct: 2615 SVEPVFSVVPPVT 2627 Score = 42.4 bits (98), Expect = 0.002 Identities = 81/355 (22%), Positives = 123/355 (34%), Gaps = 83/355 (23%) Query: 479 RSSGQLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPT 538 + + QL S S+ L P P R+ SL P P PP P P P PP Sbjct: 2371 KPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPP 2430 Query: 539 TGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQ---------SG 589 T +P P + SP + P TL ++ S + Sbjct: 2431 T--------SPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTA 2482 Query: 590 TPTLPPKGLAGP----------PASPGKA-QPPKPERVTSLRSP--------GASVSSSL 630 P +PPK + P P+ P A +P P+ T+ + P G S++SS+ Sbjct: 2483 PPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSM 2542 Query: 631 TSLCSSSSD---PAP-------SDRSGPQILTPLGDRFVI---PPHPKVPA--------- 668 T +S+D P+P S++S P+ L + +V+ P P P Sbjct: 2543 TLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAIT 2602 Query: 669 --PFSPPPSKPRSPNP---AAPALAAPAV---------VPGPVSTTDASPQSPPT----P 710 P P S P P + A + + G + T A+P + P+ Sbjct: 2603 SWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAPSSFQAA 2662 Query: 711 QTTLTPLQESPVISKDQSPPPSPPP-------SYHPPPPPTKKPEVVVEAPSASE 758 T++T + V + S S P S PP P + +E P E Sbjct: 2663 PTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPPEPLALDNIHLEKPQYKE 2717 Score = 34.3 bits (77), Expect = 0.66 Identities = 35/165 (21%), Positives = 56/165 (33%), Gaps = 21/165 (12%) Query: 673 PPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPS 732 PP + P P ++ V + P+SP + ++PL + P Sbjct: 3586 PPKDKKRPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKALESAFVPYEK 3645 Query: 733 PPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEE 792 P P P P++ P++ +TA+ + + P P +P + S A F Sbjct: 3646 PLPD-DISPQKVLHPDMAKVPPASPKTAK--MMQRSMSDPKPLSPTADESSRAPF----- 3697 Query: 793 AFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPP 837 E GS + SS A T P+PPP Sbjct: 3698 -----QYTEGYTTKGSQTMTSSGAQKKVKRTL--------PNPPP 3729 Score = 32.3 bits (72), Expect = 2.5 Identities = 13/30 (43%), Positives = 15/30 (50%) Query: 1010 RPPQAPKKSPKAPPPVARKPSVGVPPPASP 1039 +PP P P PPP P +PPP SP Sbjct: 2404 QPPPPPPPPPPPPPPPPPPPPPPLPPPTSP 2433 Score = 30.8 bits (68), Expect = 7.3 Identities = 20/51 (39%), Positives = 21/51 (41%), Gaps = 12/51 (23%) Query: 1006 ISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEPLTAPPTNGLP 1056 IS Q PP P P PPP PPP P P P T+P LP Sbjct: 2401 ISAQPPPPPP---PPPPPP---------PPPPPPPPPPLPPPTSPKPTILP 2439 >gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens] Length = 1003 Score = 106 bits (265), Expect = 1e-22 Identities = 153/553 (27%), Positives = 200/553 (36%), Gaps = 112/553 (20%) Query: 530 QPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSG 589 +P PPTT + G G+ P P + P L+ G PPR + PS G SS Sbjct: 146 RPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLADPV--PSGGSSS--- 200 Query: 590 TPTLPPKGLAGPPASPGKAQPPKPERVTSLRSP----GASVSSSLTSLCSSSSDPAPSDR 645 P P+G A PA PP P + SL +P GA++ SSL S PAP Sbjct: 201 -PRFLPRGNAPSPA------PPPPPAI-SLNAPSYNWGAALRSSLVP-SDLGSPPAPHAS 251 Query: 646 SGPQILTPL---GDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPV--STT 700 S P PL D PP P P+ P P S P + A +V GP+ + T Sbjct: 252 SSPPSDPPLFHCSDALTPPPLP--PSNNLPAHPGPASQPPVSSATMHLPLVLGPLGGAPT 309 Query: 701 DASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEA---PSAS 757 P +PP ++L +K Q PP PP + P + P + PS Sbjct: 310 VEGPGAPPFLASSLLS-----AAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSSLRPSQR 364 Query: 758 ETAEEPL----------QDPNWPPPPPPAPEEQDLSMAD----FPPPEEAFFSVASPEPA 803 P Q P P PAP Q S+ + P + + +P P+ Sbjct: 365 RPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPS 424 Query: 804 GPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGC 863 GS L+ S A T GSP P P P+ + G ++ +P Sbjct: 425 HSDGSFNLLGSDAHLPPPPTLSS----GSPPQPRHPIQPSLPGTTSGSLSSVP------- 473 Query: 864 SKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPV 923 G P AP+V +LQ S G GA GP+ P PL G A P Sbjct: 474 --GAPAPPAASKAPVVPSPVLQSP---SEGLGMGA-----GPACPLPPLA---GGEAFPF 520 Query: 924 PAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQL 983 P+P GL A S A G+ A P P + +PP SP Sbjct: 521 PSPEQGL-------ALSGAGFPGMLGALPL--PLSLGQPPPSPL---------------- 555 Query: 984 ERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPR 1043 L +L L Q PP+ P PPP P + P PS Sbjct: 556 -----------LNHSLFGVLTGGGGQPPPE-----PLLPPPGGPGPPLAPGEPEGPSLLV 599 Query: 1044 AEPLTAPPTNGLP 1056 A L PP++ LP Sbjct: 600 ASLLPPPPSDLLP 612 Score = 95.1 bits (235), Expect = 3e-19 Identities = 201/807 (24%), Positives = 273/807 (33%), Gaps = 174/807 (21%) Query: 310 TGTRAPPLTRPMSLAVPG--LTGGAGPAEPLSPAMSISPQATYLSKLIPHAVLPPTV--D 365 T + PP RP P L GG G P P++S + + P + PP + Sbjct: 137 TVSPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVS----QAFPTLAGPGGLFPPRLADP 192 Query: 366 VVALGRCSLRTLSRCSLHSASPASVRSLGRFSSVSSPQPRSRHPSSSSDTWSHSQSSDTI 425 V + G S R L R + S +P P P + ++ S W + S + Sbjct: 193 VPSGGSSSPRFLPRGNAPSPAP--------------PPPPAISLNAPSYNWGAALRSSLV 238 Query: 426 VSDGSTLSSKGGSEGQPESST---ASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSG 482 SD + + S P S+++ PPP S G ++ Sbjct: 239 PSDLGSPPAPHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQ----------- 287 Query: 483 QLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGS 542 PP + ++H L + GPLG P E P P + Sbjct: 288 -----------------PPVSSATMH---LPLVLGPLGGAPTVEG---PGAPPFLASSLL 324 Query: 543 EGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPP---KGLA 599 A A PP P S + G R PR+ + S SS P PP + L Sbjct: 325 SAAAKAQHPPLPPPSTLQG-------RRPRAQAPSASHSSSLRPSQRRPRRPPTVFRLLE 377 Query: 600 GP-PASPGKAQPPKPERVT---SLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLG 655 G P +P +++P P V SL P + S+ SL + P PS G L LG Sbjct: 378 GRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPT-PGPSHSDGSFNL--LG 434 Query: 656 DRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLT 715 +PP P + + P P P P+ P G +S+ P +P P + Sbjct: 435 SDAHLPPPPTLSSGSPPQPRHPIQPS-------LPGTTSGSLSSV---PGAPAPPAASKA 484 Query: 716 PLQESPVISKDQSP---------PPSP-PPSYHPPPPPTKKPEVVVEAPSAS---ETAEE 762 P+ SPV+ QSP P P PP P PE + A Sbjct: 485 PVVPSPVL---QSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGAL 541 Query: 763 PLQDPNWPPPPPPAPEEQDLSM----ADFPPPEEAFFSVASPEPAGPSGSPELVSSPAAS 818 PL PPP P + PPPE P P GP G P P Sbjct: 542 PLPLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLL-----PPPGGP-GPPLAPGEPEGP 595 Query: 819 SSSATALQIQPPGSPDPPP-APPAPAPASSAP----GHVAKLPQKEPVGCSKGGGPPRED 873 S +L PP PPP APP+ AS P G A + G G P Sbjct: 596 SLLVASLLPPPPSDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFSG 655 Query: 874 VG--APLVTPSLLQ---MVRLRS------VGAPGGAPTPALGPSAPQ------------- 909 +G +PL+ P L ++ L S + P G P SAPQ Sbjct: 656 LGDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAPQPGPPTSSVTTATT 715 Query: 910 ----KPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGL--SSAQPNGP-------- 955 L +A S P S L A++ SL +S G S QP GP Sbjct: 716 DPGASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSLLQPPGPLLSGQLGL 775 Query: 956 ---PEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPP 1012 P PP S AS+ + S ++ E+P +P + + P Sbjct: 776 QLLPGGGAPPPLSEASSPLACLLQ-SLQIPPEQPEAP---------------CLPPESPA 819 Query: 1013 QAPKKSPKAPPPVARKPSVGVPPPASP 1039 A + P PP A P G P P P Sbjct: 820 SALEPEPARPPLSALAPPHGSPDPPVP 846 Score = 78.6 bits (192), Expect = 3e-14 Identities = 123/492 (25%), Positives = 165/492 (33%), Gaps = 115/492 (23%) Query: 602 PASPGKAQ--PPKPERVTSL---RSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGD 656 P +PG A P E +T L R ++++ S+ ++ S +P + + PQ+ Sbjct: 81 PVTPGGAGVGPASEEDMTKLCNHRRKAVAMATLYRSMETTCSHSSPGEGASPQMF----- 135 Query: 657 RFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTP 716 V P P P PP+ P + P + + P P S + A P + P P Sbjct: 136 HTVSPGPPSARPPCRVPPTTPLNGGPGS-------LPPEPPSVSQAFP-TLAGPGGLFPP 187 Query: 717 LQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPS----------------ASETA 760 PV S S P P P P P P + + APS S A Sbjct: 188 RLADPVPSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPA 247 Query: 761 EEPLQDPNWPPP---------PPPAPEEQDLSM----ADFPPPEEAFFSVASPEPAGPSG 807 P PP PPP P +L A PP A + P GP G Sbjct: 248 PHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHL--PLVLGPLG 305 Query: 808 SPELVSSPAA-----SSSSATALQIQPPGSPDPPPA------PPAPAPASSAPGHVA--- 853 V P A SS + A + Q P P PPP+ P A AP++S + Sbjct: 306 GAPTVEGPGAPPFLASSLLSAAAKAQHP--PLPPPSTLQGRRPRAQAPSASHSSSLRPSQ 363 Query: 854 KLPQKEPV--GCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKP 911 + P++ P +G GP Q R AP P P P Q Sbjct: 364 RRPRRPPTVFRLLEGRGP---------------QTPRRSRPRAPAPVPQPFSLPEPSQPI 408 Query: 912 LRRALSGRASPVPAPSSGLHAAVRLKA-CSLAASEGLSSAQPNGPPEAEPRPPQSPASTA 970 L LS P P PS + L + L LSS P P P P P +T+ Sbjct: 409 LPSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSP--PQPRHPIQPSLPGTTS 466 Query: 971 SFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPS 1030 L S+ P A K+P P PV + PS Sbjct: 467 G------------------------------SLSSVPGAPAPPAASKAPVVPSPVLQSPS 496 Query: 1031 VGVPPPASPSYP 1042 G+ A P+ P Sbjct: 497 EGLGMGAGPACP 508 Score = 65.1 bits (157), Expect = 4e-10 Identities = 112/445 (25%), Positives = 154/445 (34%), Gaps = 68/445 (15%) Query: 397 SSVSSPQPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPESSTAS---NSVVP 453 SS S PQPR HP S + S S LSS G+ P +S A + V+ Sbjct: 446 SSGSPPQPR--HPIQPSLPGTTSGS----------LSSVPGAPAPPAASKAPVVPSPVLQ 493 Query: 454 PPQGGSGRGS-------PSGGSTA------EASDTLSIRSSGQLSGRSVSLRKLKRPPPP 500 P G G G+ P G A E LS + G L +PPP Sbjct: 494 SPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPS 553 Query: 501 PRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGS-EGAG---AAPCPPNPAN 556 P HSL V G G PP P P PP G EG A+ PP P++ Sbjct: 554 PLLNHSL----FGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVASLLPPPPSD 609 Query: 557 SWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQ------- 609 P +P + P L P++G S +G GP P Sbjct: 610 LLPPPSAPPSNLLASFLPLLALGPTAGDGEGSA------EGAGGPSGEPFSGLGDLSPLL 663 Query: 610 -PPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPA 668 PP T + A ++++L S + P P S PQ P P + Sbjct: 664 FPPLSAPPTLIALNSALLAATLDP--PSGTPPQPCVLSAPQPGPPTSSVTTATTDPGASS 721 Query: 669 PFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQS 728 P + R P +P L A + G +S+ +SP + P+ PL + + Sbjct: 722 LGKAPSNSGRPPQLLSPLLGASLL--GDLSSLTSSPGALPSLLQPPGPLLSGQLGLQLLP 779 Query: 729 PPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFP 788 +PPP + EA S + LQ P P P P E S + Sbjct: 780 GGGAPPP--------------LSEASSPLACLLQSLQIPPEQPEAPCLPPESPASALEPE 825 Query: 789 PPEEAFFSVASPEPAGPSGSPELVS 813 P ++A P + PEL++ Sbjct: 826 PARPPLSALAPPHGSPDPPVPELLT 850 Score = 34.7 bits (78), Expect = 0.51 Identities = 46/181 (25%), Positives = 64/181 (35%), Gaps = 14/181 (7%) Query: 441 QPESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPPP 500 +PE + S + PP G P T S R G L G + R + P Sbjct: 823 EPEPARPPLSALAPPHGSPDPPVPEL-LTGRGSGKRGRRGGGGLRGINGEARPARGRKPG 881 Query: 501 PRRTHSLHQRGLAVPDGPLG-----LPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPA 555 RR LA+ G G + P R Q GG+E P P+ Sbjct: 882 SRREPGR----LALKWGTRGGFNGQMERSPRRTHHWQHNGELAEGGAEPKDPPPPGPHSE 937 Query: 556 NSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPAS-PGKAQPPKPE 614 + VP PG R+ R R +P+ +S TL P A P +A+P +P Sbjct: 938 DLKVP---PGVVRKSRRGRRRKYNPTRNSNSSRQDITLEPSPTARAAVPLPPRARPGRPA 994 Query: 615 R 615 + Sbjct: 995 K 995 >gi|116284392 mucin 2 precursor [Homo sapiens] Length = 5179 Score = 105 bits (263), Expect = 2e-22 Identities = 96/381 (25%), Positives = 137/381 (35%), Gaps = 42/381 (11%) Query: 497 PPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPR----PPTTGGSEGAGAAPCPP 552 P PPP T +L P P P P + PPTT S PP Sbjct: 1406 PSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPP 1465 Query: 553 NPANSWVPGLSPGGSRRPPRSPERTLS---PSSGYSSQSGTP--------TLPPKGLAGP 601 P +P P P T + P++ S + TP TLPP P Sbjct: 1466 PTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSP 1525 Query: 602 PASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIP 661 P + PP +P +S+ T +++ P P+ + P T Sbjct: 1526 PTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTT 1585 Query: 662 PHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESP 721 P P +PPP+ SP P P P +TT P +PPT TTL P Sbjct: 1586 PSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTT---PITPPTSTTTLPP----- 1637 Query: 722 VISKDQSPPP----SPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAP 777 + SPPP +PPP+ P PP T P P + T P P+ P P+P Sbjct: 1638 --TTTPSPPPTTTTTPPPTTTPSPPTTTTP----SPPITTTTTPPPTTTPSSPITTTPSP 1691 Query: 778 EEQDLSM-ADFPPPEEAFFSVASP-EPAGPSGSPELVSSPAAS---SSSATALQIQPPGS 832 ++ + P + +P PS P +++P+ + S T + PP + Sbjct: 1692 PTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTT 1751 Query: 833 PDPP----PAPPAPAPASSAP 849 P P PP+ P + +P Sbjct: 1752 TSSPLTTTPLPPSITPPTFSP 1772 Score = 94.7 bits (234), Expect = 4e-19 Identities = 93/371 (25%), Positives = 144/371 (38%), Gaps = 51/371 (13%) Query: 564 PGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLA-GPPASPGKAQPPKPERVTSLRSP 622 P + PP + TL P++ S + T T PP PP + PP +P Sbjct: 1402 PTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPP-------TTTP 1454 Query: 623 GASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNP 682 +S++ T +++ P P+ P TP P P SPP + P +P P Sbjct: 1455 SPPISTTTTPPPTTTPSP-PTTTPSPPTTTPSPPTTTTTTPPPTTTP-SPPTTTPITP-P 1511 Query: 683 AAPALAAPAVVPGPVSTTDASPQSPPTPQ-TTLTPLQESPVISKDQSPP---PSPPPSYH 738 A+ P P P +TT +P TP T TP+ +P S PP PSPPP+ Sbjct: 1512 ASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPI--TPPTSTTTLPPTTTPSPPPTTT 1569 Query: 739 PPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPP-PPPAPEEQDLSMADFPPPEEAFFSV 797 PPPT P +P + T P PPP P+P + PPP Sbjct: 1570 TTPPPTTTP-----SPPTTTTPSPPTITTTTPPPTTTPSP---PTTTTTTPPP------- 1614 Query: 798 ASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQ 857 + P+ P+ +P ++ P ++++ + P +P PPP P ++ P Sbjct: 1615 -TTTPSPPTTTP--ITPPTSTTT------LPPTTTPSPPPTTTTTPPPTTTPSPPTTTTP 1665 Query: 858 KEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALS 917 P+ + PP +P+ T + + P+P PS+P S Sbjct: 1666 SPPI-TTTTTPPPTTTPSSPITTTPSPPTTTMTT-------PSPTTTPSSPITTTTTP-S 1716 Query: 918 GRASPVPAPSS 928 +P P P++ Sbjct: 1717 STTTPSPPPTT 1727 Score = 72.4 bits (176), Expect = 2e-12 Identities = 153/816 (18%), Positives = 271/816 (33%), Gaps = 104/816 (12%) Query: 304 TFVGRSTGTRAPPLTRPMSLAVPGLTGGAGPAE-PLSPAMSISPQATYLSKLIPHAVLPP 362 T G T T P T P TG P P++ +++P T P P Sbjct: 3499 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTP 3552 Query: 363 TVDVVALGRCSLRTLSRCSLHSASPASVRSLGRFSSVSSPQPRSRHPSSSSDTWSHSQSS 422 T + T + + + + + ++ +P P P+ + + ++ Sbjct: 3553 TTTPITTTTTVTPTPTPTGTQTPTTTPITT----TTTVTPTPT---PTGTQTPTTTPITT 3605 Query: 423 DTIVSDGSTLSSKGGSEGQPESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSG 482 T V+ T + P ++T + + P P G + +T + T + + Sbjct: 3606 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3665 Query: 483 QLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGS 542 + ++ P P P T + + + P P P + PTT Sbjct: 3666 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT---VTPTPT----PTGTQTPTTTPI 3718 Query: 543 EGAGAAPCPPNPANSWVPGLSPGGSRR---PPRSPERTLSPSSG--YSSQSGTPTLPPKG 597 P P + P +P + P +P T +P++ ++ + TPT P G Sbjct: 3719 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3778 Query: 598 LAGPPASP---GKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPL 654 P +P P P T ++P ++ +T+ + + P P+ P TP+ Sbjct: 3779 TQTPTTTPITTTTTVTPTPTP-TGTQTP---TTTPITTTTTVTPTPTPTGTQTPTT-TPI 3833 Query: 655 GDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTL 714 + P +P P+ ++P P V P P T +P + TP TT Sbjct: 3834 TTTTTVTP--------TPTPTGTQTPT-TTPITTTTTVTPTPTPTGTQTPTT--TPITTT 3882 Query: 715 TPLQESPVISKDQSPPPSP---PPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPP 771 T + +P + Q+P +P + P P PT + P + T P P Sbjct: 3883 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQ 3941 Query: 772 PPPPAPEEQDLSMADFPPPEEA---------FFSVASPEPAGPSGSPELVSSPAASSSSA 822 P P ++ P P + +P P P+G+ ++P ++++ Sbjct: 3942 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQTPTTTPITTTTTV 4000 Query: 823 TALQIQPPGSPDPPPAP--------PAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDV 874 T P G+ P P P P P + + P P+ + P Sbjct: 4001 TPTPT-PTGTQTPTTTPITTTTTVTPTPTPTGT------QTPTTTPITTTTTVTPTPTPT 4053 Query: 875 GAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAV 934 G TP+ + +V PTP P+ Q P ++ + P P+ Sbjct: 4054 GTQ--TPTTTPITTTTTV-----TPTPT--PTGTQTPTTTPITTTTTVTPTPTP-----T 4099 Query: 935 RLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQAD 994 + + ++ P P P +P +T + + + P +T Sbjct: 4100 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-------PTGTQTPTT 4152 Query: 995 LQRNLVAELRSISEQRPPQAPKKSP------KAPPPVARKPSVGVPPPASPSYPRAEPLT 1048 + Q P +P P P G PP + + P AE T Sbjct: 4153 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTG-PPTHTSTAPIAELTT 4211 Query: 1049 A--PPTNGLPHTQDRTKRELAENGGVLQLVGPEEKM 1082 + PP + P T T L E+ +L + P +M Sbjct: 4212 SNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEM 4247 Score = 67.8 bits (164), Expect = 5e-11 Identities = 161/768 (20%), Positives = 260/768 (33%), Gaps = 124/768 (16%) Query: 304 TFVGRSTGTRAPPLTRPMSLAVPGLTGGAGPAE-PLSPAMSISPQATYLSKLIPHAVLPP 362 T G T T P T P TG P P++ +++P T P P Sbjct: 3752 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTP 3805 Query: 363 TVDVVALGRCSLRTLSRCSLHSASPASVRSLGRFSSVSSPQPRSRHPSSSSDTWSHSQSS 422 T + T + + + + + ++ +P P P+ + + ++ Sbjct: 3806 TTTPITTTTTVTPTPTPTGTQTPTTTPITT----TTTVTPTPT---PTGTQTPTTTPITT 3858 Query: 423 DTIVSDGSTLSSKGGSEGQPESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSG 482 T V+ T + P ++T + + P P G + +T + T + + Sbjct: 3859 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3918 Query: 483 QLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGS 542 + ++ P P P T + + + P P P + PTT Sbjct: 3919 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT---VTPTPT----PTGTQTPTTTPI 3971 Query: 543 EGAGAAPCPPNPANSWVPGLSPGGSRR---PPRSPERTLSPSSG--YSSQSGTPTLPPKG 597 P P + P +P + P +P T +P++ ++ + TPT P G Sbjct: 3972 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 4031 Query: 598 LAGPPASP---GKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPL 654 P +P P P T ++P ++ +T+ + + P P+ P TP+ Sbjct: 4032 TQTPTTTPITTTTTVTPTPTP-TGTQTP---TTTPITTTTTVTPTPTPTGTQTPTT-TPI 4086 Query: 655 GDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPP-TPQTT 713 + P +P P+ ++P P V P P T +P + P T TT Sbjct: 4087 TTTTTVTP--------TPTPTGTQTPT-TTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 4137 Query: 714 LTPLQESPVISKDQSPPPSP---PPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWP 770 +TP +P + Q+P +P + P P PT + P + T P P Sbjct: 4138 VTP---TPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGT 4193 Query: 771 PPPPPAPEE----QDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQ 826 PP +L+ ++ PPPE ++P+ + + SP + S T L Sbjct: 4194 QTGPPTHTSTAPIAELTTSN-PPPES-----STPQTSRSTSSP--------LTESTTLLS 4239 Query: 827 IQPPGSPDPPPAPPA--PAPASSAPGHVAKLPQKEPVGCSKGGGPPREDV--GAPLVTPS 882 PP APP+ AP +++ GH P S G P R + TPS Sbjct: 4240 TLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTT--SPPGTPTRGTTTGSSSAPTPS 4297 Query: 883 LLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLA 942 +Q + A PTP PS + R P PSS L V L A Sbjct: 4298 TVQTT---TTSAWTPTPTPLSTPSIIRTTGLR---------PYPSSVLICCV-LNDTYYA 4344 Query: 943 ASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAE 1002 E + + + T F+ S L+ P T + Sbjct: 4345 PGEEVYNG--------------TYGDTCYFVNCSLSCTLEFYNWSCPSTPS--------- 4381 Query: 1003 LRSISEQRPPQAPKKS---PKAPPPVARKPSVGVPPPASPSY--PRAE 1045 P P KS P P KP+ G PP P + PR E Sbjct: 4382 --------PTPTPSKSTPTPSKPSSTPSKPTPGTKPPECPDFDPPRQE 4421 Score = 63.5 bits (153), Expect = 1e-09 Identities = 82/368 (22%), Positives = 117/368 (31%), Gaps = 121/368 (32%) Query: 694 PGPVSTTDASPQSPPTPQTTLTPLQE-SPVISKDQSPPP----SPPPSYHPPPPPTKKPE 748 P P +TT P PPT TTL P SP + +PPP SPP + PPPT P Sbjct: 1399 PSPPTTT---PSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPS 1455 Query: 749 VVVEAPSASETAEEPLQDPNWP---PPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGP 805 P ++ T P P+ P P PP + PPP + P+ P Sbjct: 1456 ----PPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPP--------TTTPSPP 1503 Query: 806 SGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSK 865 + +P ++ PA++++ + P +P PP P ++ P P P + Sbjct: 1504 TTTP--ITPPASTTT------LPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTT 1555 Query: 866 GGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPA 925 PP P T + P P PS P + P+ Sbjct: 1556 L--PPTTTPSPPPTTTT---------------TPPPTTTPSPP-----------TTTTPS 1587 Query: 926 PSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLER 985 P + +++ P PP P PP + +T Sbjct: 1588 PPT------------------ITTTTP--PPTTTPSPPTTTTTT---------------- 1611 Query: 986 PVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPS-VGVPPPASPSYPRA 1044 PP SP P+ S +PP +PS P Sbjct: 1612 -------------------------PPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPT 1646 Query: 1045 EPLTAPPT 1052 T PPT Sbjct: 1647 TTTTPPPT 1654 Score = 61.2 bits (147), Expect = 5e-09 Identities = 137/772 (17%), Positives = 240/772 (31%), Gaps = 87/772 (11%) Query: 304 TFVGRSTGTRAPPLTRPMSLAVPGLTGGAGPAE-PLSPAMSISPQATYLSKLIPHAVLPP 362 T G T T P T P TG P P++ +++P T P P Sbjct: 2073 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTP 2126 Query: 363 TVDVVALGRCSLRTLSRCSLHSASPASVRSLGRFSSVSSPQPRSRHPSSSSDTWSHSQSS 422 T + T + + + + + ++ +P P P+ + + ++ Sbjct: 2127 TTTPITTTTTVTPTPTPTGTQTPTTTPITT----TTTVTPTPT---PTGTQTPTTTPITT 2179 Query: 423 DTIVSDGSTLSSKGGSEGQPESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSG 482 T V+ T + P ++T + + P P G + +T + T + + Sbjct: 2180 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2239 Query: 483 QLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGS 542 + ++ P P P T + + + P P P + PTT Sbjct: 2240 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT---VTPTPT----PTGTQTPTTTPI 2292 Query: 543 EGAGAAPCPPNPANSWVPGLSPGGSRR---PPRSPERTLSPSSG--YSSQSGTPTLPPKG 597 P P + P +P + P +P T +P++ ++ + TPT P G Sbjct: 2293 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2352 Query: 598 LAGPPASP---GKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPL 654 P +P P P T ++P ++ +T+ + + P P+ P TP+ Sbjct: 2353 TQTPTTTPITTTTTVTPTPTP-TGTQTP---TTTPITTTTTVTPTPTPTGTQTPTT-TPI 2407 Query: 655 GDRFVIPPHPKVPAPFSPPPSKPRS------PNPAAPALAAPAVVPGPVSTTDASPQSPP 708 + P P P P + P + P P P P TT + P Sbjct: 2408 TTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTP 2463 Query: 709 TPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPN 768 TP T TP + +P P+P + P P V P+ + T Sbjct: 2464 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2523 Query: 769 WPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQ 828 P P P + +P P P+G+ ++P ++++ T Sbjct: 2524 TTTTVTPTPTPTGTQTPTTTPITTT--TTVTPTPT-PTGTQTPTTTPITTTTTVTPTP-T 2579 Query: 829 PPGSPDPPPAP--------PAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVT 880 P G+ P P P P P + + P P+ + P G T Sbjct: 2580 PTGTQTPTTTPITTTTTVTPTPTPTGT------QTPTTTPITTTTTVTPTPTPTGTQ--T 2631 Query: 881 PSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACS 940 P+ + +V PTP P+ Q P ++ + P P+ + + Sbjct: 2632 PTTTPITTTTTV-----TPTPT--PTGTQTPTTTPITTTTTVTPTPT-----PTGTQTPT 2679 Query: 941 LAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLV 1000 ++ P P P +P +T + + P T Sbjct: 2680 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-----------TPTPTPTGTQTPTTTP 2728 Query: 1001 AELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEPLTAPPT 1052 + P ++P P P P P P+T T Sbjct: 2729 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2780 Score = 61.2 bits (147), Expect = 5e-09 Identities = 137/772 (17%), Positives = 240/772 (31%), Gaps = 87/772 (11%) Query: 304 TFVGRSTGTRAPPLTRPMSLAVPGLTGGAGPAE-PLSPAMSISPQATYLSKLIPHAVLPP 362 T G T T P T P TG P P++ +++P T P P Sbjct: 2349 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTP 2402 Query: 363 TVDVVALGRCSLRTLSRCSLHSASPASVRSLGRFSSVSSPQPRSRHPSSSSDTWSHSQSS 422 T + T + + + + + ++ +P P P+ + + ++ Sbjct: 2403 TTTPITTTTTVTPTPTPTGTQTPTTTPITT----TTTVTPTPT---PTGTQTPTTTPITT 2455 Query: 423 DTIVSDGSTLSSKGGSEGQPESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSG 482 T V+ T + P ++T + + P P G + +T + T + + Sbjct: 2456 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2515 Query: 483 QLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGS 542 + ++ P P P T + + + P P P + PTT Sbjct: 2516 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT---VTPTPT----PTGTQTPTTTPI 2568 Query: 543 EGAGAAPCPPNPANSWVPGLSPGGSRR---PPRSPERTLSPSSG--YSSQSGTPTLPPKG 597 P P + P +P + P +P T +P++ ++ + TPT P G Sbjct: 2569 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2628 Query: 598 LAGPPASP---GKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPL 654 P +P P P T ++P ++ +T+ + + P P+ P TP+ Sbjct: 2629 TQTPTTTPITTTTTVTPTPTP-TGTQTP---TTTPITTTTTVTPTPTPTGTQTPTT-TPI 2683 Query: 655 GDRFVIPPHPKVPAPFSPPPSKPRS------PNPAAPALAAPAVVPGPVSTTDASPQSPP 708 + P P P P + P + P P P P TT + P Sbjct: 2684 TTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTP 2739 Query: 709 TPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPN 768 TP T TP + +P P+P + P P V P+ + T Sbjct: 2740 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2799 Query: 769 WPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQ 828 P P P + +P P P+G+ ++P ++++ T Sbjct: 2800 TTTTVTPTPTPTGTQTPTTTPITTT--TTVTPTPT-PTGTQTPTTTPITTTTTVTPTP-T 2855 Query: 829 PPGSPDPPPAP--------PAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVT 880 P G+ P P P P P + + P P+ + P G T Sbjct: 2856 PTGTQTPTTTPITTTTTVTPTPTPTGT------QTPTTTPITTTTTVTPTPTPTGTQ--T 2907 Query: 881 PSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACS 940 P+ + +V PTP P+ Q P ++ + P P+ + + Sbjct: 2908 PTTTPITTTTTV-----TPTPT--PTGTQTPTTTPITTTTTVTPTPT-----PTGTQTPT 2955 Query: 941 LAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLV 1000 ++ P P P +P +T + + P T Sbjct: 2956 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-----------TPTPTPTGTQTPTTTP 3004 Query: 1001 AELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEPLTAPPT 1052 + P ++P P P P P P+T T Sbjct: 3005 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3056 Score = 61.2 bits (147), Expect = 5e-09 Identities = 137/772 (17%), Positives = 240/772 (31%), Gaps = 87/772 (11%) Query: 304 TFVGRSTGTRAPPLTRPMSLAVPGLTGGAGPAE-PLSPAMSISPQATYLSKLIPHAVLPP 362 T G T T P T P TG P P++ +++P T P P Sbjct: 2625 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTP 2678 Query: 363 TVDVVALGRCSLRTLSRCSLHSASPASVRSLGRFSSVSSPQPRSRHPSSSSDTWSHSQSS 422 T + T + + + + + ++ +P P P+ + + ++ Sbjct: 2679 TTTPITTTTTVTPTPTPTGTQTPTTTPITT----TTTVTPTPT---PTGTQTPTTTPITT 2731 Query: 423 DTIVSDGSTLSSKGGSEGQPESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSG 482 T V+ T + P ++T + + P P G + +T + T + + Sbjct: 2732 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2791 Query: 483 QLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGS 542 + ++ P P P T + + + P P P + PTT Sbjct: 2792 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT---VTPTPT----PTGTQTPTTTPI 2844 Query: 543 EGAGAAPCPPNPANSWVPGLSPGGSRR---PPRSPERTLSPSSG--YSSQSGTPTLPPKG 597 P P + P +P + P +P T +P++ ++ + TPT P G Sbjct: 2845 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2904 Query: 598 LAGPPASP---GKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPL 654 P +P P P T ++P ++ +T+ + + P P+ P TP+ Sbjct: 2905 TQTPTTTPITTTTTVTPTPTP-TGTQTP---TTTPITTTTTVTPTPTPTGTQTPTT-TPI 2959 Query: 655 GDRFVIPPHPKVPAPFSPPPSKPRS------PNPAAPALAAPAVVPGPVSTTDASPQSPP 708 + P P P P + P + P P P P TT + P Sbjct: 2960 TTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTP 3015 Query: 709 TPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPN 768 TP T TP + +P P+P + P P V P+ + T Sbjct: 3016 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3075 Query: 769 WPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQ 828 P P P + +P P P+G+ ++P ++++ T Sbjct: 3076 TTTTVTPTPTPTGTQTPTTTPITTT--TTVTPTPT-PTGTQTPTTTPITTTTTVTPTP-T 3131 Query: 829 PPGSPDPPPAP--------PAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVT 880 P G+ P P P P P + + P P+ + P G T Sbjct: 3132 PTGTQTPTTTPITTTTTVTPTPTPTGT------QTPTTTPITTTTTVTPTPTPTGTQ--T 3183 Query: 881 PSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACS 940 P+ + +V PTP P+ Q P ++ + P P+ + + Sbjct: 3184 PTTTPITTTTTV-----TPTPT--PTGTQTPTTTPITTTTTVTPTPT-----PTGTQTPT 3231 Query: 941 LAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLV 1000 ++ P P P +P +T + + P T Sbjct: 3232 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-----------TPTPTPTGTQTPTTTP 3280 Query: 1001 AELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEPLTAPPT 1052 + P ++P P P P P P+T T Sbjct: 3281 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3332 Score = 61.2 bits (147), Expect = 5e-09 Identities = 137/772 (17%), Positives = 240/772 (31%), Gaps = 87/772 (11%) Query: 304 TFVGRSTGTRAPPLTRPMSLAVPGLTGGAGPAE-PLSPAMSISPQATYLSKLIPHAVLPP 362 T G T T P T P TG P P++ +++P T P P Sbjct: 2901 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTP 2954 Query: 363 TVDVVALGRCSLRTLSRCSLHSASPASVRSLGRFSSVSSPQPRSRHPSSSSDTWSHSQSS 422 T + T + + + + + ++ +P P P+ + + ++ Sbjct: 2955 TTTPITTTTTVTPTPTPTGTQTPTTTPITT----TTTVTPTPT---PTGTQTPTTTPITT 3007 Query: 423 DTIVSDGSTLSSKGGSEGQPESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSG 482 T V+ T + P ++T + + P P G + +T + T + + Sbjct: 3008 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3067 Query: 483 QLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGS 542 + ++ P P P T + + + P P P + PTT Sbjct: 3068 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT---VTPTPT----PTGTQTPTTTPI 3120 Query: 543 EGAGAAPCPPNPANSWVPGLSPGGSRR---PPRSPERTLSPSSG--YSSQSGTPTLPPKG 597 P P + P +P + P +P T +P++ ++ + TPT P G Sbjct: 3121 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3180 Query: 598 LAGPPASP---GKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPL 654 P +P P P T ++P ++ +T+ + + P P+ P TP+ Sbjct: 3181 TQTPTTTPITTTTTVTPTPTP-TGTQTP---TTTPITTTTTVTPTPTPTGTQTPTT-TPI 3235 Query: 655 GDRFVIPPHPKVPAPFSPPPSKPRS------PNPAAPALAAPAVVPGPVSTTDASPQSPP 708 + P P P P + P + P P P P TT + P Sbjct: 3236 TTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTP 3291 Query: 709 TPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPN 768 TP T TP + +P P+P + P P V P+ + T Sbjct: 3292 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3351 Query: 769 WPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQ 828 P P P + +P P P+G+ ++P ++++ T Sbjct: 3352 TTTTVTPTPTPTGTQTPTTTPITTT--TTVTPTPT-PTGTQTPTTTPITTTTTVTPTP-T 3407 Query: 829 PPGSPDPPPAP--------PAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVT 880 P G+ P P P P P + + P P+ + P G T Sbjct: 3408 PTGTQTPTTTPITTTTTVTPTPTPTGT------QTPTTTPITTTTTVTPTPTPTGTQ--T 3459 Query: 881 PSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACS 940 P+ + +V PTP P+ Q P ++ + P P+ + + Sbjct: 3460 PTTTPITTTTTV-----TPTPT--PTGTQTPTTTPITTTTTVTPTPT-----PTGTQTPT 3507 Query: 941 LAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLV 1000 ++ P P P +P +T + + P T Sbjct: 3508 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-----------TPTPTPTGTQTPTTTP 3556 Query: 1001 AELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEPLTAPPT 1052 + P ++P P P P P P+T T Sbjct: 3557 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3608 Score = 61.2 bits (147), Expect = 5e-09 Identities = 137/772 (17%), Positives = 240/772 (31%), Gaps = 87/772 (11%) Query: 304 TFVGRSTGTRAPPLTRPMSLAVPGLTGGAGPAE-PLSPAMSISPQATYLSKLIPHAVLPP 362 T G T T P T P TG P P++ +++P T P P Sbjct: 3177 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTP 3230 Query: 363 TVDVVALGRCSLRTLSRCSLHSASPASVRSLGRFSSVSSPQPRSRHPSSSSDTWSHSQSS 422 T + T + + + + + ++ +P P P+ + + ++ Sbjct: 3231 TTTPITTTTTVTPTPTPTGTQTPTTTPITT----TTTVTPTPT---PTGTQTPTTTPITT 3283 Query: 423 DTIVSDGSTLSSKGGSEGQPESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSG 482 T V+ T + P ++T + + P P G + +T + T + + Sbjct: 3284 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3343 Query: 483 QLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGS 542 + ++ P P P T + + + P P P + PTT Sbjct: 3344 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT---VTPTPT----PTGTQTPTTTPI 3396 Query: 543 EGAGAAPCPPNPANSWVPGLSPGGSRR---PPRSPERTLSPSSG--YSSQSGTPTLPPKG 597 P P + P +P + P +P T +P++ ++ + TPT P G Sbjct: 3397 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3456 Query: 598 LAGPPASP---GKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPL 654 P +P P P T ++P ++ +T+ + + P P+ P TP+ Sbjct: 3457 TQTPTTTPITTTTTVTPTPTP-TGTQTP---TTTPITTTTTVTPTPTPTGTQTPTT-TPI 3511 Query: 655 GDRFVIPPHPKVPAPFSPPPSKPRS------PNPAAPALAAPAVVPGPVSTTDASPQSPP 708 + P P P P + P + P P P P TT + P Sbjct: 3512 TTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTP 3567 Query: 709 TPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPN 768 TP T TP + +P P+P + P P V P+ + T Sbjct: 3568 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3627 Query: 769 WPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQ 828 P P P + +P P P+G+ ++P ++++ T Sbjct: 3628 TTTTVTPTPTPTGTQTPTTTPITTT--TTVTPTPT-PTGTQTPTTTPITTTTTVTPTP-T 3683 Query: 829 PPGSPDPPPAP--------PAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVT 880 P G+ P P P P P + + P P+ + P G T Sbjct: 3684 PTGTQTPTTTPITTTTTVTPTPTPTGT------QTPTTTPITTTTTVTPTPTPTGTQ--T 3735 Query: 881 PSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACS 940 P+ + +V PTP P+ Q P ++ + P P+ + + Sbjct: 3736 PTTTPITTTTTV-----TPTPT--PTGTQTPTTTPITTTTTVTPTPT-----PTGTQTPT 3783 Query: 941 LAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLV 1000 ++ P P P +P +T + + P T Sbjct: 3784 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-----------TPTPTPTGTQTPTTTP 3832 Query: 1001 AELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEPLTAPPT 1052 + P ++P P P P P P+T T Sbjct: 3833 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3884 Score = 58.5 bits (140), Expect = 3e-08 Identities = 99/533 (18%), Positives = 164/533 (30%), Gaps = 71/533 (13%) Query: 537 PTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPK 596 PT G++ P + P +P G++ P +P T + + TPT P Sbjct: 2026 PTPTGTQTPTTTPI--TTTTTVTPTPTPTGTQTPTTTPITTTT--------TVTPTPTPT 2075 Query: 597 GLAGPPASP---GKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTP 653 G P +P P P T ++P ++ +T+ + + P P+ P TP Sbjct: 2076 GTQTPTTTPITTTTTVTPTPTP-TGTQTP---TTTPITTTTTVTPTPTPTGTQTPTT-TP 2130 Query: 654 LGDRFVIPPHPKVPAPFSPPPSKPRS------PNPAAPALAAPAVVPGPVSTTDASPQSP 707 + + P P P P + P + P P P P TT + Sbjct: 2131 ITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP---ITTTTTVTPT 2186 Query: 708 PTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDP 767 PTP T TP + +P P+P + P P V P+ + T Sbjct: 2187 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2246 Query: 768 NWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQI 827 P P P + +P P P+G+ ++P ++++ T Sbjct: 2247 TTTTTVTPTPTPTGTQTPTTTPITTT--TTVTPTPT-PTGTQTPTTTPITTTTTVTPTP- 2302 Query: 828 QPPGSPDPPPAP--------PAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLV 879 P G+ P P P P P + + P P+ + P G Sbjct: 2303 TPTGTQTPTTTPITTTTTVTPTPTPTGT------QTPTTTPITTTTTVTPTPTPTGTQ-- 2354 Query: 880 TPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKAC 939 TP+ + +V PTP P+ Q P ++ + P P+ + Sbjct: 2355 TPTTTPITTTTTV-----TPTPT--PTGTQTPTTTPITTTTTVTPTPT-----PTGTQTP 2402 Query: 940 SLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNL 999 + ++ P P P +P +T + + P T Sbjct: 2403 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-----------TPTPTPTGTQTPTTT 2451 Query: 1000 VAELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEPLTAPPT 1052 + P ++P P P P P P+T T Sbjct: 2452 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2504 Score = 54.7 bits (130), Expect = 5e-07 Identities = 144/791 (18%), Positives = 236/791 (29%), Gaps = 98/791 (12%) Query: 309 STGTRAPPLTRPMSLAVPGLTGGAGPAEPLSPAMSISPQATYLSKLIPHAVLPPTVDVVA 368 +T T PP T P +T A L P + SP T + P P Sbjct: 1489 TTTTTPPPTTTPSPPTTTPITPPASTTT-LPPTTTPSPPTTTTTTPPPTTTPSPPTTTPI 1547 Query: 369 LGRCSLRTLSRCSLHSASPASVRSLGRFSSVSSPQPRSRHPSSSSDTW-------SHSQS 421 S TL + S P + + ++ S P + P + + T S + Sbjct: 1548 TPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTT 1607 Query: 422 SDTIVSDGSTLSSKGGSEGQPESSTAS------------NSVVPPPQGGSGRGSPSGGST 469 + T +T S + P +ST + + PPP +PS +T Sbjct: 1608 TTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTT-----TPSPPTT 1662 Query: 470 AEASDTLSIRSSGQLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQ 529 S ++ ++ + S + P PP T + P P+ P Sbjct: 1663 TTPSPPITTTTTPPPTTTPSS--PITTTPSPPTTTMTTPSP-TTTPSSPITTTTTPSSTT 1719 Query: 530 QPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGG----SRRPPRSPERTLSPSSGYS 585 P PPTT + P PP + +P + + PP T SP S + Sbjct: 1720 TPS--PPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFS--T 1775 Query: 586 SQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDP-APSD 644 + TP +P G S GK KP T L + C ++ P P Sbjct: 1776 TTPTTPCVPLCNWTGWLDS-GKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPDVPIG 1834 Query: 645 RSGPQILTPLGDRFVIPPHPKVPAPFSPPP---------------SKPRSPNPAAPALAA 689 + G ++ + + + P P ++P + Sbjct: 1835 QLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPT 1894 Query: 690 PAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEV 749 P +TT +P PTP T TP + +P P+P + P P Sbjct: 1895 PPTTTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 1952 Query: 750 VVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSP 809 V P+ + T P P P + +P P P+G+ Sbjct: 1953 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT--TTVTPTPT-PTGTQ 2009 Query: 810 ELVSSPAASSSSATALQIQPPGSPDPPPAP--------PAPAPASSAPGHVAKLPQKEPV 861 ++P ++++ T P G+ P P P P P + + P P+ Sbjct: 2010 TPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGT------QTPTTTPI 2062 Query: 862 GCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRAS 921 + P G TP+ + +V PTP P+ Q P ++ + Sbjct: 2063 TTTTTVTPTPTPTGTQ--TPTTTPITTTTTV-----TPTPT--PTGTQTPTTTPITTTTT 2113 Query: 922 PVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKL 981 P P+ + + ++ P P P +P +T + + Sbjct: 2114 VTPTPT-----PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-------- 2160 Query: 982 QLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSY 1041 P T + P ++P P P P Sbjct: 2161 ---TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2217 Query: 1042 PRAEPLTAPPT 1052 P P+T T Sbjct: 2218 PTTTPITTTTT 2228 Score = 37.4 bits (85), Expect = 0.078 Identities = 45/222 (20%), Positives = 65/222 (29%), Gaps = 45/222 (20%) Query: 832 SPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRS 891 +P PP P+P P S+ P P + PP P+ T + Sbjct: 1398 TPSPPTTTPSPPPTSTTTLPPTTTPS--PPTTTTTTPPPTTTPSPPITTTT--------- 1446 Query: 892 VGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQ 951 P P PS P +S +P P + + + ++ Sbjct: 1447 ------TPPPTTTPSPP-------ISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTT 1493 Query: 952 PNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRP 1011 P PP P PP + T P + L + + P Sbjct: 1494 P--PPTTTPSPPTTTPITP------------------PASTTTLPPTTTPSPPTTTTTTP 1533 Query: 1012 PQAPKKSPKAPPPVARKPS-VGVPPPASPSYPRAEPLTAPPT 1052 P SP P+ S +PP +PS P T PPT Sbjct: 1534 PPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPT 1575 Score = 36.6 bits (83), Expect = 0.13 Identities = 31/148 (20%), Positives = 50/148 (33%), Gaps = 8/148 (5%) Query: 911 PLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQS----- 965 P+ + ++ + P PS + L + + ++ P PP P PP + Sbjct: 1391 PMDKCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTP--PPTTTPSPPITTTTTP 1448 Query: 966 -PASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPP 1024 P +T S S + P P T + + + PP P P Sbjct: 1449 PPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPI 1508 Query: 1025 VARKPSVGVPPPASPSYPRAEPLTAPPT 1052 + +PP +PS P T PPT Sbjct: 1509 TPPASTTTLPPTTTPSPPTTTTTTPPPT 1536 >gi|189181724 proteoglycan 4 isoform D [Homo sapiens] Length = 1270 Score = 104 bits (259), Expect = 5e-22 Identities = 140/633 (22%), Positives = 222/633 (35%), Gaps = 70/633 (11%) Query: 453 PPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPPP-PRRTHSLHQRG 511 PP +G G +G DT + + + + ++ K P P P + + + Sbjct: 82 PPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETS 141 Query: 512 LAVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGS--RR 569 L V E K+ + +T G E +A + + L+P + Sbjct: 142 LTV-----NKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK 196 Query: 570 PPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSS 629 P E T + + + TPT P + PAS +P ++ +P ++ Sbjct: 197 PTPKAETTTKGPALTTPKEPTPTTPKE-----PASTTPKEPTPTTIKSAPTTPKEPAPTT 251 Query: 630 LTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPP--PSKPRSPNPAAPAL 687 S ++ +PAP+ P TP + P K PAP + P+ P+ P P P Sbjct: 252 TKSAPTTPKEPAPTTTKEPAPTTP---KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 308 Query: 688 AAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKP 747 AP P TT P +P TP+ P + P + + P P+ P P P K+P Sbjct: 309 PAPTTPKEPAPTTPKEP-TPTTPKEP-APTTKEPAPTTPKEPAPTAPKK--PAPTTPKEP 364 Query: 748 EVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSG 807 A T +EP P P P P + + P P + +P+ P+ Sbjct: 365 APTTPKEPAPTTTKEP--SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT 422 Query: 808 SPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPA-PASSAPGHVAKLPQKEPVGCSKG 866 + E +P A +P + PAP P PA + A KEP + Sbjct: 423 TKE--PAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPK 480 Query: 867 GGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAP 926 P +TP+ + + + P L P+ P++P + PAP Sbjct: 481 ETAPTTP---KKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP-----TPTTPEEPAP 532 Query: 927 SSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTA----SFIFSKGSRKLQ 982 ++ AA P P E P P+ PA T + KG+ Sbjct: 533 TTP----------KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTT 582 Query: 983 LERPV--SPETQA--DLQRNLVAELRSISEQRP---------PQAPKK----SPKAPPPV 1025 L+ P +P+ A +L E S + +P P PK+ +PK P P Sbjct: 583 LKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPT 642 Query: 1026 ARKPSVGV----PPPASPSYPRAEPLTAPPTNG 1054 K + P P +P P + L T G Sbjct: 643 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKG 675 Score = 102 bits (253), Expect = 3e-21 Identities = 153/726 (21%), Positives = 239/726 (32%), Gaps = 82/726 (11%) Query: 403 QPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPESSTASNSVVPPPQGGSGRG 462 +P S P + T S + +T S + +P +T P+ + Sbjct: 223 EPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTT 282 Query: 463 SPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPP--PPRRTHSLHQRGLAVPDGPLG 520 + T S + + + + + K P P P T + + P Sbjct: 283 TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAP 342 Query: 521 LPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSP 580 PK P+ P P T E A P P P + P S P+ P T + Sbjct: 343 TTPKEPAPTAPKKPAPTTP--KEPAPTTPKEPAPTTTKEP------SPTTPKEPAPTTTK 394 Query: 581 SSGYSSQSGTPTLPPKGLAGPPA-SPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSD 639 S+ +++ PT P SP + P P T+ + P + ++ + Sbjct: 395 SAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP---TTPKEPAPTTPKKPAP--TTPKE 449 Query: 640 PAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPN---PAAPALAAPAVVPGP 696 PAP+ P P + P PK PAP +P + P +P P P AP P Sbjct: 450 PAPTTPKEP---APTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKP 506 Query: 697 VSTT--DASPQSP--PTPQTT-----LTPLQESPVISKDQSP--PPSPPPSYHPPPPPTK 745 TT + +P +P PTP T TP +P K+ +P P P P+ P PT Sbjct: 507 APTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT 566 Query: 746 KPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFP----------------- 788 E P TA L++P P PAP+E + P Sbjct: 567 PKETAPTTPKG--TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA 624 Query: 789 ---PPEEAFFSVASPEPAGPSGS-PELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAP 844 P E A + P P P G+ P + PA ++ A + P + P + + P Sbjct: 625 PTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP 684 Query: 845 ASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALG 904 A + P A KEP + P P T + + +P + Sbjct: 685 APTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDEST- 743 Query: 905 PSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQ 964 P +P +AL P++ AA + + + A + + PE P+ Sbjct: 744 PELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTT-TAKDKTTERDLRTTPETTTAAPK 802 Query: 965 SPASTASFIFSKGSRKLQLERP-VSPETQADLQRNLVAELRSIS---------------- 1007 TA+ K+ V+ T D + L++ + Sbjct: 803 MTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTE 862 Query: 1008 ------EQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEP-LTAPPTNGLPHTQD 1060 E P+ + KA P +KP+ P S P+ P + P T P Sbjct: 863 IMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMT 922 Query: 1061 RTKREL 1066 T EL Sbjct: 923 STMPEL 928 Score = 84.7 bits (208), Expect = 4e-16 Identities = 108/479 (22%), Positives = 171/479 (35%), Gaps = 59/479 (12%) Query: 400 SSPQPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPESSTASNSVVPPPQ--G 457 ++ +P P + T + S + T +T S + +P +T P+ Sbjct: 376 TTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPA 435 Query: 458 GSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDG 517 + P+ + E + T + + + + P P+ T P Sbjct: 436 PTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET---------APTT 486 Query: 518 PLGLPPKPERKQQPQLP-RPPTTGGSEGAGAAPCPPNPANSWVPG------LSPGGSRRP 570 P L P K P P +P T E A P P P P +P + P Sbjct: 487 PKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEP 546 Query: 571 ----PRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASV 626 P+ P T ++ T PKG A P + + P P++ + Sbjct: 547 APTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA--PTTLKEPAPTTPKKPAPKELAPTTT 604 Query: 627 SSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRS------- 679 ++ C PAP+ G TP + P PK PAP +P + P + Sbjct: 605 KEPTSTTCDK---PAPTTPKGTAPTTP---KEPAPTTPKEPAPTTPKGTAPTTLKEPAPT 658 Query: 680 -PNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTT--LTPLQESPVISKDQSP--PPSPP 734 P AP AP GP STT P +P TP+ T TP + +P K +P P +PP Sbjct: 659 TPKKPAPKELAPTTTKGPTSTTSDKP-APTTPKETAPTTPKEPAPTTPKKPAPTTPETPP 717 Query: 735 P--SYHPPPPPTKKPEVVVEAP--SASETAEEPL--------QDPNWPPPPPPAPEEQDL 782 P S P TK+P + ++P S E + EP ++P P PA + ++ Sbjct: 718 PTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEM 777 Query: 783 -SMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSS---ATALQIQPPGSPDPPP 837 + A E + A P + E ++ ++ S AT Q+ + D P Sbjct: 778 TTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTP 836 Score = 42.4 bits (98), Expect = 0.002 Identities = 75/348 (21%), Positives = 107/348 (30%), Gaps = 65/348 (18%) Query: 743 PTKKPEVVVEAPSASETAEEPLQDPNWPP-------------------PPPPAPEEQDLS 783 PT KP VV EA S + + + P+ P P P D S Sbjct: 78 PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTS 137 Query: 784 -----MADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGS-----P 833 + E + + + G + S+ S T+ + P S P Sbjct: 138 KETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP 197 Query: 834 DPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVG 893 P PA + P KEP + P+E TP+ ++S Sbjct: 198 TPKAETTTKGPALTTPKEPTPTTPKEPASTT-----PKEP------TPT-----TIKSAP 241 Query: 894 APGGAPTPALGPSAPQKPLRRALSGRASPVP-APSSGLHAAVRLKACSLAASEGLSSAQP 952 P P SAP P A + P P P + A + S P Sbjct: 242 TTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKS------AP 295 Query: 953 NGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPP 1012 P E P P+ PA T K + P +P T + + ++ P Sbjct: 296 TTPKEPAPTTPKKPAPTT----PKEPAPTTPKEP-TPTTPKEPAPTTKEPAPTTPKEPAP 350 Query: 1013 QAPKK----SPKAPPPVARK----PSVGVPPPASPSYPRAEPLTAPPT 1052 APKK +PK P P K + P P +P P + PT Sbjct: 351 TAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPT 398 >gi|189181722 proteoglycan 4 isoform C [Homo sapiens] Length = 1311 Score = 104 bits (259), Expect = 5e-22 Identities = 140/633 (22%), Positives = 222/633 (35%), Gaps = 70/633 (11%) Query: 453 PPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPPP-PRRTHSLHQRG 511 PP +G G +G DT + + + + ++ K P P P + + + Sbjct: 123 PPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETS 182 Query: 512 LAVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGS--RR 569 L V E K+ + +T G E +A + + L+P + Sbjct: 183 LTV-----NKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK 237 Query: 570 PPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSS 629 P E T + + + TPT P + PAS +P ++ +P ++ Sbjct: 238 PTPKAETTTKGPALTTPKEPTPTTPKE-----PASTTPKEPTPTTIKSAPTTPKEPAPTT 292 Query: 630 LTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPP--PSKPRSPNPAAPAL 687 S ++ +PAP+ P TP + P K PAP + P+ P+ P P P Sbjct: 293 TKSAPTTPKEPAPTTTKEPAPTTP---KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 349 Query: 688 AAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKP 747 AP P TT P +P TP+ P + P + + P P+ P P P K+P Sbjct: 350 PAPTTPKEPAPTTPKEP-TPTTPKEP-APTTKEPAPTTPKEPAPTAPKK--PAPTTPKEP 405 Query: 748 EVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSG 807 A T +EP P P P P + + P P + +P+ P+ Sbjct: 406 APTTPKEPAPTTTKEP--SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT 463 Query: 808 SPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPA-PASSAPGHVAKLPQKEPVGCSKG 866 + E +P A +P + PAP P PA + A KEP + Sbjct: 464 TKE--PAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPK 521 Query: 867 GGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAP 926 P +TP+ + + + P L P+ P++P + PAP Sbjct: 522 ETAPTTP---KKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP-----TPTTPEEPAP 573 Query: 927 SSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTA----SFIFSKGSRKLQ 982 ++ AA P P E P P+ PA T + KG+ Sbjct: 574 TTP----------KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTT 623 Query: 983 LERPV--SPETQA--DLQRNLVAELRSISEQRP---------PQAPKK----SPKAPPPV 1025 L+ P +P+ A +L E S + +P P PK+ +PK P P Sbjct: 624 LKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPT 683 Query: 1026 ARKPSVGV----PPPASPSYPRAEPLTAPPTNG 1054 K + P P +P P + L T G Sbjct: 684 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKG 716 Score = 102 bits (253), Expect = 3e-21 Identities = 153/726 (21%), Positives = 239/726 (32%), Gaps = 82/726 (11%) Query: 403 QPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPESSTASNSVVPPPQGGSGRG 462 +P S P + T S + +T S + +P +T P+ + Sbjct: 264 EPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTT 323 Query: 463 SPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPP--PPRRTHSLHQRGLAVPDGPLG 520 + T S + + + + + K P P P T + + P Sbjct: 324 TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAP 383 Query: 521 LPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSP 580 PK P+ P P T E A P P P + P S P+ P T + Sbjct: 384 TTPKEPAPTAPKKPAPTTP--KEPAPTTPKEPAPTTTKEP------SPTTPKEPAPTTTK 435 Query: 581 SSGYSSQSGTPTLPPKGLAGPPA-SPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSD 639 S+ +++ PT P SP + P P T+ + P + ++ + Sbjct: 436 SAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP---TTPKEPAPTTPKKPAP--TTPKE 490 Query: 640 PAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPN---PAAPALAAPAVVPGP 696 PAP+ P P + P PK PAP +P + P +P P P AP P Sbjct: 491 PAPTTPKEP---APTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKP 547 Query: 697 VSTT--DASPQSP--PTPQTT-----LTPLQESPVISKDQSP--PPSPPPSYHPPPPPTK 745 TT + +P +P PTP T TP +P K+ +P P P P+ P PT Sbjct: 548 APTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT 607 Query: 746 KPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFP----------------- 788 E P TA L++P P PAP+E + P Sbjct: 608 PKETAPTTPKG--TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA 665 Query: 789 ---PPEEAFFSVASPEPAGPSGS-PELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAP 844 P E A + P P P G+ P + PA ++ A + P + P + + P Sbjct: 666 PTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP 725 Query: 845 ASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALG 904 A + P A KEP + P P T + + +P + Sbjct: 726 APTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDEST- 784 Query: 905 PSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQ 964 P +P +AL P++ AA + + + A + + PE P+ Sbjct: 785 PELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTT-TAKDKTTERDLRTTPETTTAAPK 843 Query: 965 SPASTASFIFSKGSRKLQLERP-VSPETQADLQRNLVAELRSIS---------------- 1007 TA+ K+ V+ T D + L++ + Sbjct: 844 MTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTE 903 Query: 1008 ------EQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEP-LTAPPTNGLPHTQD 1060 E P+ + KA P +KP+ P S P+ P + P T P Sbjct: 904 IMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMT 963 Query: 1061 RTKREL 1066 T EL Sbjct: 964 STMPEL 969 Score = 84.7 bits (208), Expect = 4e-16 Identities = 108/479 (22%), Positives = 171/479 (35%), Gaps = 59/479 (12%) Query: 400 SSPQPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPESSTASNSVVPPPQ--G 457 ++ +P P + T + S + T +T S + +P +T P+ Sbjct: 417 TTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPA 476 Query: 458 GSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDG 517 + P+ + E + T + + + + P P+ T P Sbjct: 477 PTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET---------APTT 527 Query: 518 PLGLPPKPERKQQPQLP-RPPTTGGSEGAGAAPCPPNPANSWVPG------LSPGGSRRP 570 P L P K P P +P T E A P P P P +P + P Sbjct: 528 PKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEP 587 Query: 571 ----PRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASV 626 P+ P T ++ T PKG A P + + P P++ + Sbjct: 588 APTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA--PTTLKEPAPTTPKKPAPKELAPTTT 645 Query: 627 SSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRS------- 679 ++ C PAP+ G TP + P PK PAP +P + P + Sbjct: 646 KEPTSTTCDK---PAPTTPKGTAPTTP---KEPAPTTPKEPAPTTPKGTAPTTLKEPAPT 699 Query: 680 -PNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTT--LTPLQESPVISKDQSP--PPSPP 734 P AP AP GP STT P +P TP+ T TP + +P K +P P +PP Sbjct: 700 TPKKPAPKELAPTTTKGPTSTTSDKP-APTTPKETAPTTPKEPAPTTPKKPAPTTPETPP 758 Query: 735 P--SYHPPPPPTKKPEVVVEAP--SASETAEEPL--------QDPNWPPPPPPAPEEQDL 782 P S P TK+P + ++P S E + EP ++P P PA + ++ Sbjct: 759 PTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEM 818 Query: 783 -SMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSS---ATALQIQPPGSPDPPP 837 + A E + A P + E ++ ++ S AT Q+ + D P Sbjct: 819 TTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTP 877 Score = 42.4 bits (98), Expect = 0.002 Identities = 75/348 (21%), Positives = 107/348 (30%), Gaps = 65/348 (18%) Query: 743 PTKKPEVVVEAPSASETAEEPLQDPNWPP-------------------PPPPAPEEQDLS 783 PT KP VV EA S + + + P+ P P P D S Sbjct: 119 PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTS 178 Query: 784 -----MADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGS-----P 833 + E + + + G + S+ S T+ + P S P Sbjct: 179 KETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP 238 Query: 834 DPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVG 893 P PA + P KEP + P+E TP+ ++S Sbjct: 239 TPKAETTTKGPALTTPKEPTPTTPKEPASTT-----PKEP------TPT-----TIKSAP 282 Query: 894 APGGAPTPALGPSAPQKPLRRALSGRASPVP-APSSGLHAAVRLKACSLAASEGLSSAQP 952 P P SAP P A + P P P + A + S P Sbjct: 283 TTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKS------AP 336 Query: 953 NGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPP 1012 P E P P+ PA T K + P +P T + + ++ P Sbjct: 337 TTPKEPAPTTPKKPAPTT----PKEPAPTTPKEP-TPTTPKEPAPTTKEPAPTTPKEPAP 391 Query: 1013 QAPKK----SPKAPPPVARK----PSVGVPPPASPSYPRAEPLTAPPT 1052 APKK +PK P P K + P P +P P + PT Sbjct: 392 TAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPT 439 >gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 preproprotein [Homo sapiens] Length = 331 Score = 101 bits (251), Expect = 4e-21 Identities = 101/372 (27%), Positives = 127/372 (34%), Gaps = 102/372 (27%) Query: 493 KLKRPPPPPRRTHSLHQRGLAVPDGP------LGLPPKPERKQQPQLPR-----PPTTGG 541 K + PPPPP + +G P GP G PP+ ++ + P+ P PP GG Sbjct: 46 KPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGG 105 Query: 542 SEGAGAAPCPPNPANSWVPGLSPGGSRRP--PRSPERTLSPSSGYSSQSGTPTLPPKG-- 597 ++ G P P P G P G RP P P + P PP+G Sbjct: 106 NQPQGPPPPPGKPQ-----GPPPQGGNRPQGPPPPGKPQGP-------------PPQGDK 147 Query: 598 LAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDR 657 P + PGK Q P P+ + P P P GP Sbjct: 148 SRSPRSPPGKPQGPPPQGGNQPQGP----------------PPPPGKPQGP--------- 182 Query: 658 FVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPL 717 PP PPP KP+ P P + PG PQ PP PQ P Sbjct: 183 ---PPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPG-------KPQGPP-PQGGNQPQ 231 Query: 718 QESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAP 777 P K Q PPP PPPP K + S S++A PP P P Sbjct: 232 GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARS-------PPGKPQGP 284 Query: 778 EEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPP 837 +Q+ + PPP PAG G+P+ +P P G P PP Sbjct: 285 PQQEGNNPQGPPP-----------PAG--GNPQQPQAP-------------PAGQPQGPP 318 Query: 838 APPAPAPASSAP 849 PP S P Sbjct: 319 RPPQGGRPSRPP 330 Score = 100 bits (248), Expect = 1e-20 Identities = 95/312 (30%), Positives = 109/312 (34%), Gaps = 43/312 (13%) Query: 579 SPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSS 638 SP G Q G P P K PP K Q P P P S S S Sbjct: 40 SPQGGNKPQ-GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQ 98 Query: 639 DPAPSDRSGPQILTPLGDRFVIPP-----HPKVPAPFSPPPSKPRSPNPAAPALAAPAVV 693 P P + PQ P + PP P+ P PPP KP+ P P +P Sbjct: 99 GPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGP----PPPGKPQGPPPQGDKSRSPRSP 154 Query: 694 PGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEA 753 PG PQ PP PQ P P K Q PPP PPPP KP+ Sbjct: 155 PG-------KPQGPP-PQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPP-GKPQGPPPQ 205 Query: 754 PSASETAEEPLQDPNWPPP--------PPPAPEEQDLSMADFPPPEEAFFSVASPEPAGP 805 S +++ P P PPP PPP P PPP+ P P P Sbjct: 206 GDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPP-----GKPQGPPPQGGNKPQGPPPPGKP 260 Query: 806 SGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAP--GHVAKLPQKEPVGC 863 G P S + S+ S PPG P PP P P G + PQ P G Sbjct: 261 QGPPAQGGSKSQSARS-------PPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAG- 312 Query: 864 SKGGGPPREDVG 875 + GPPR G Sbjct: 313 -QPQGPPRPPQG 323 Score = 91.7 bits (226), Expect = 3e-18 Identities = 95/353 (26%), Positives = 118/353 (33%), Gaps = 67/353 (18%) Query: 625 SVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPP-SKPRSPNPA 683 S S + + + P+P + PQ P + PP P PPP KP+ P P Sbjct: 24 SQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQ 83 Query: 684 APALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPS--------PPP 735 +P PG PQ PP PQ P P K Q PPP PPP Sbjct: 84 GDKSRSPRSPPG-------KPQGPP-PQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPP 135 Query: 736 SYHPPPPPTKKPEVVVEAPSASETAEEPL--QDPNWPPPPPPAPEEQDLSMADFPPPEEA 793 PPP +P P P PPPPP P+ PPP+ Sbjct: 136 GKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQG--------PPPQGG 187 Query: 794 FFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVA 853 P P P G P +S S Q PP + P PP P P Sbjct: 188 KKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP---- 243 Query: 854 KLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPAL--GPSAPQKP 911 P G +K GPP G P P A GG+ + + P PQ P Sbjct: 244 -----PPQGGNKPQGPP--PPGKPQGPP------------AQGGSKSQSARSPPGKPQGP 284 Query: 912 LRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQ 964 ++ + P P P+ G + A P G P+ PRPPQ Sbjct: 285 PQQEGNNPQGP-PPPAGG--------------NPQQPQAPPAGQPQGPPRPPQ 322 Score = 89.0 bits (219), Expect = 2e-17 Identities = 106/396 (26%), Positives = 128/396 (32%), Gaps = 98/396 (24%) Query: 637 SSDPAPSDRSG-PQILTPLGDRFVIPPHPKVPAPFSPPP---SKPRSPNPAAPALAAPAV 692 S + +PS +G PQ +P G P P P PPP +KP+ P P P Sbjct: 24 SQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP-- 81 Query: 693 VPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVE 752 P SP+SPP K Q PPP PPPP KP+ Sbjct: 82 ---PQGDKSRSPRSPP---------------GKPQGPPPQGGNQPQGPPPPPGKPQ---- 119 Query: 753 APSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELV 812 P Q N P PPP + Q PPP+ S P P G P+ Sbjct: 120 --------GPPPQGGNRPQGPPPPGKPQG------PPPQ----GDKSRSPRSPPGKPQ-- 159 Query: 813 SSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPRE 872 P + QP G P PP P P P K PQ P G PP+ Sbjct: 160 -GPPPQGGN------QPQGPPPPPGKPQGPPPQGG------KKPQGPPPPGKPQGPPPQG 206 Query: 873 DVGAPLVTPSLLQMVRLRSVGAPGGAPT-----PALGPSAPQKPLRRALSGRASPVPAPS 927 D +P G P G P P P P KP G P P Sbjct: 207 DKSRSSQSPP----------GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP 256 Query: 928 SGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPV 987 G + S + S +P GPP+ E PQ P A G Q + P Sbjct: 257 PGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPA------GGNPQQPQAPP 310 Query: 988 SPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPP 1023 + + Q RPPQ + P PP Sbjct: 311 AGQPQ--------------GPPRPPQGGR--PSRPP 330 Score = 80.1 bits (196), Expect = 1e-14 Identities = 93/375 (24%), Positives = 112/375 (29%), Gaps = 104/375 (27%) Query: 703 SPQSPPTPQTTLTPLQESPVISKDQSPPPS--------PPPSYHPPPPPTKKPEVVVEAP 754 +PQ P +PQ P P K Q PPP PPP PPP +P Sbjct: 35 NPQGP-SPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSP 93 Query: 755 SASETAEEPL--QDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELV 812 P P PPPPP P+ PPP+ P P P G P Sbjct: 94 PGKPQGPPPQGGNQPQGPPPPPGKPQG--------PPPQGGNRPQGPPPPGKPQGPPPQG 145 Query: 813 SSPAASSSSATALQIQPP-GSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPR 871 + S Q PP G P PP P P K PQ P G PP+ Sbjct: 146 DKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQ 205 Query: 872 EDVGAPLVTPSLLQMVRLRSVGAPGGAPT--PALGPSAPQKPLRRALSGRASPVPAPSSG 929 D + RS +P G P P G + PQ P P P Sbjct: 206 GD--------------KSRSSQSPPGKPQGPPPQGGNQPQ-----------GPPPPPG-- 238 Query: 930 LHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSP 989 +P GPP PQ P +P P Sbjct: 239 ---------------------KPQGPPPQGGNKPQGPPPPG--------------KPQGP 263 Query: 990 ETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPA--SPSYPRAEPL 1047 Q S+ + ++P P+ PP G PPPA +P P+A P Sbjct: 264 PAQGG------------SKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPA 311 Query: 1048 ------TAPPTNGLP 1056 PP G P Sbjct: 312 GQPQGPPRPPQGGRP 326 Score = 70.5 bits (171), Expect = 8e-12 Identities = 88/332 (26%), Positives = 104/332 (31%), Gaps = 95/332 (28%) Query: 718 QESPVISKDQSPPPSPPPSYHP--PPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPP 775 +ESP + PSP P PPPP KP+ P Q N P PPP Sbjct: 26 EESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQ------------GPPPQGGNKPQGPPP 73 Query: 776 APEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDP 835 + Q PPP+ S P P G P+ P + QP G P P Sbjct: 74 PGKPQG------PPPQ----GDKSRSPRSPPGKPQ---GPPPQGGN------QPQGPPPP 114 Query: 836 PPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAP 895 P P P P PQ P G PP+ D + RS +P Sbjct: 115 PGKPQGPPPQGG------NRPQGPPPPGKPQGPPPQGD--------------KSRSPRSP 154 Query: 896 GGAPT--PALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPN 953 G P P G + PQ P P P G +P Sbjct: 155 PGKPQGPPPQGGNQPQGP---------PPPPGKPQG--------------PPPQGGKKPQ 191 Query: 954 GPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQ 1013 GPP P PQ P S + +P P Q Q Q PP Sbjct: 192 GPPP--PGKPQGPPPQGD---KSRSSQSPPGKPQGPPPQGGNQ-----------PQGPPP 235 Query: 1014 APKKSPKAPPPVARKPSVGVPPPASPSYPRAE 1045 P K P+ PPP G PPP P P A+ Sbjct: 236 PPGK-PQGPPPQGGNKPQGPPPPGKPQGPPAQ 266 Score = 47.0 bits (110), Expect = 1e-04 Identities = 45/180 (25%), Positives = 65/180 (36%), Gaps = 30/180 (16%) Query: 435 KGGSEGQPESSTASNSVVPPPQGGSG----------RGSPSGGSTAEASDTLSIRSSGQL 484 +GG++ Q PPPQGG +G P G + +S + + G Sbjct: 164 QGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPP 223 Query: 485 SGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGSEG 544 + + PPPPP + +G P GP P P + Q P P GGS+ Sbjct: 224 PQGG---NQPQGPPPPPGKPQGPPPQGGNKPQGP----PPPGKPQGP-----PAQGGSKS 271 Query: 545 AGAAPCPPNPA--------NSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPK 596 A P P N P GG+ + P++P Q G P+ PP+ Sbjct: 272 QSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPPQ 331 >gi|55750053 atrophin-1 [Homo sapiens] Length = 1190 Score = 100 bits (249), Expect = 8e-21 Identities = 180/714 (25%), Positives = 236/714 (33%), Gaps = 153/714 (21%) Query: 453 PP--PQGG---SGRGSPSGGSTAEASDT-LSIRSSGQLSGRSVSLRKLKRPPPPPRRTHS 506 PP P+GG S G P+GG T +S+ SSG PP + + Sbjct: 231 PPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGA-------------PPTKPPT 277 Query: 507 LHQRGLAVPDGPLGLPPKPERKQQPQLPRPPT-------TGGSEGAGAAPCPPNPANSWV 559 G +P P PP P LP PP + G GA P P + + Sbjct: 278 TPVGGGNLPSAP---PPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHA 334 Query: 560 PGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSL 619 G GG P PE+ PTL P + PPAS PP +S Sbjct: 335 MGQGMGGL---PPGPEKG-------------PTLAPSPHSLPPASSSAPAPPMRFPYSSS 378 Query: 620 RSPGASVSSSLTSLCSSSSDPAPSDR---SGPQILTPLGDRFVIPPHPKVPAPFSPPPS- 675 S A+ SSS +S SSS+ P P+ + S P P V PK P P + Sbjct: 379 SSSSAAASSS-SSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAV 437 Query: 676 ---KPRSPNPAAPALAAPAVVPGPV-STTDASPQSPPTPQTTLTPLQESPVISKDQSPPP 731 P P P LA PGP +T A + P T Q+ + Q Sbjct: 438 WSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQ 497 Query: 732 SPPPSYH---PPPPPTKKPEVVVEAPS--ASETAEEPLQDPNWPPPPPPAPEEQDLSMAD 786 +H PPPP P + S A A P P PP P A Sbjct: 498 QQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGP---------AH 548 Query: 787 FPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAP-- 844 PPP S S AGP+G P SS ++SS+S + P P P P P Sbjct: 549 LPPPH----SQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPV 604 Query: 845 -----------------ASSAPGHVAKLPQKEP--------VGCSKGGGPPREDVGAPLV 879 ASS G+ P P G K PP G+P Sbjct: 605 PTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSP-- 662 Query: 880 TPSLLQMV--RLRSVGAPG-------GAPTPALGPSAPQKPLRRALSGRASPVPAPSSGL 930 PS R P G+PT GP P P L P AP+SG Sbjct: 663 -PSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGP--SGLPSLPPPPAAPASGP 719 Query: 931 H-AAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSP 989 +A ++K +E + + PP P PP S L+R + Sbjct: 720 PLSATQIKQ---EPAEEYETPESPVPPARSPSPPPKVVDVPSHASQSARFNKHLDRGFNS 776 Query: 990 ETQADL-------------QRNLVAELRSISEQRPPQAPKKSPKAPPPVARK-------- 1028 ++DL + +LV ++R +EQR + ++ + R+ Sbjct: 777 CARSDLYFVPLEGSKLAKKRADLVEKVRREAEQRAREEKEREREREREKEREREKERELE 836 Query: 1029 ---------------PSVGVPPPASPSYPRAEPLTAPPTNGLPHTQDRTKRELA 1067 PS+G P P P + T PP G RT E A Sbjct: 837 RSVKLAQEGRAPVECPSLGPVPHRPPFEPGSAVATVPPYLGPDTPALRTLSEYA 890 Score = 96.7 bits (239), Expect = 1e-19 Identities = 180/764 (23%), Positives = 257/764 (33%), Gaps = 149/764 (19%) Query: 373 SLRTLSRCSLHSASPASVRSLGRFSSVSSPQPRSRHPSSSSDTWSH----SQSSDTIVSD 428 S +T + + AS V GR +S + + + T SD D Sbjct: 50 SRQTAKKARVEEASTPKVNKQGRSEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLD 109 Query: 429 GSTLSSKGGSEGQP---ESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLS 485 G +L+ G S+ + ++ + S S+ P GS SD+ S S G Sbjct: 110 GRSLNDDGSSDPRDIDQDNRSTSPSIYSP------------GSVENDSDSSSGLSQGPAR 157 Query: 486 GRSVSLRKLKRPPPP---PRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLP--RPPT-- 538 P PP PR+ + + +V P +P + Q P PP Sbjct: 158 PYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHP 217 Query: 539 ---TGGSEGAGAAPCPPNP----ANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTP 591 GG+ G + P P P A S V G + G PP +P S + + + P Sbjct: 218 QLYPGGTGGVLSGP-PMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPP 276 Query: 592 TLPPKG----LAGPPASPGKAQP--PKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDR 645 T P G A PPA+ P P P + L + AS + P P Sbjct: 277 TTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGL-------GAQPLPGHL 329 Query: 646 SGPQILTP-LGDRFVIPPHPK-----VPAPFSPPPSKPRSPNP-------AAPALAAPAV 692 P + +G +PP P+ P+P S PP+ +P P ++ + +A A Sbjct: 330 PSPHAMGQGMGG---LPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAAS 386 Query: 693 VPGPVSTTDASP----QSPPT------PQTTLTPLQESPVISKDQSP--------PPSPP 734 S++ ASP Q+ P+ P T+L+ + P ++ P PP PP Sbjct: 387 SSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPP 446 Query: 735 P--------SYHPPP-PPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMA 785 P + HP P PP+ + P ++ Q ++Q Sbjct: 447 PYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGN 506 Query: 786 DFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPA 845 PPP AF P P G + P A S S +L+ PPG PP P + Sbjct: 507 SGPPPPGAF-----PHPL--EGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPP--PHSQVS 557 Query: 846 SSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGP 905 S G P PV S P PS Q P GAP P Sbjct: 558 YSQAG-----PNGPPVSSSSNSSSSTSQGSYPCSHPSPSQ--------GPQGAPYPF--- 601 Query: 906 SAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQS 965 PVP ++ + A ++ G +A P GPP R P Sbjct: 602 ---------------PPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAP-- 644 Query: 966 PASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPV 1025 S G+ K P + + R S PP P P V Sbjct: 645 ---------SPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTS---PPAGPGTFKPGSPTV 692 Query: 1026 ARKPSVGVPPPASPS-YPRAEPLTAPPTNGLPHTQDRTKRELAE 1068 P PPA PS P P A P +G P + + K+E AE Sbjct: 693 GPGPL----PPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAE 732 Score = 86.7 bits (213), Expect = 1e-16 Identities = 209/881 (23%), Positives = 290/881 (32%), Gaps = 172/881 (19%) Query: 23 RRKKSRSGASGLRRAFSWLRGKRRKKKAAGAEGAEPAAP--RAKKAEDKAKRAKGKGRGS 80 + K S S SG ++ R + R + A G ++ +A+K+ AK+A+ + + Sbjct: 5 QNKDSMSMRSGRKKEAPGPREELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVEEAST 64 Query: 81 AKAENDKHLSVGPGQGPGSAVDEHQ-DNVFFPSGRPPHLEELHTQAQEGLRSLQHQEKQK 139 K QG + E + + P E Q+ L SL + + Sbjct: 65 PKVNK---------QGRSEEISESESEETNAPKKTKTEQELPRPQSPSDLDSL---DGRS 112 Query: 140 LNKGGWDHGDTQSIQSSRTGPDEDNISFCSQTTSYVAESSTAEDALSIRSEMIQRKGSTF 199 LN G D + I D+DN S T+ + + E+ S + Q + Sbjct: 113 LNDDG--SSDPRDI-------DQDNRS----TSPSIYSPGSVENDSDSSSGLSQGPARPY 159 Query: 200 RPHDSFPKSGK---SGRRRRER----RSTVLGLPQHVQKELGLRNEREAP-GTPRA---- 247 P FP S + S R+ E +V H E +AP G P Sbjct: 160 HPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQL 219 Query: 248 -PGARDAVRIPTVDGRPRGTSGMGARVSLQALEAEAEAGAETEAMLQRHIDRVYRDDTFV 306 PG V + G P G G GA S+ Sbjct: 220 YPGGTGGV----LSGPPMGPKGGGAASSVG------------------------------ 245 Query: 307 GRSTGTRAPPLTRPMSLAVPGLTGGAGPAEPLSPA----MSISPQATYLSKLIPHAVLPP 362 G + G + PP T P+S++ G +G P +P + +P + P+ PP Sbjct: 246 GPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPP 305 Query: 363 TVDVVALGRCSLRTLSRCSL--HSASP-ASVRSLGRF------SSVSSPQPRSRHPSSSS 413 + + S L L H SP A + +G +P P S P+SSS Sbjct: 306 ALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSS 365 Query: 414 D-------TWSHSQSSDTIVSDGSTLSSKGGSEGQPESSTAS-NSVVPPPQGGSGRGSPS 465 +S S SS S S+ SS S + S PPP S P Sbjct: 366 APAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPP 425 Query: 466 GGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKP 525 T + + ++ S G PPPPP + R LA + G P P Sbjct: 426 -KYTQPSLPSQAVWSQGP-------------PPPPP------YGRLLANSNAHPG-PFPP 464 Query: 526 ERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYS 585 Q P +T G+ PP P P G S Sbjct: 465 STGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPP-PPGAFPHPLEGGS 523 Query: 586 SQSGTP-TLPPKGLAGPPASPGKAQPPKPERVTSL-----RSPGASVSSSLTSLCSSSSD 639 S P + P + P PG A P P S P S SS+ +S S S Sbjct: 524 SHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSY 583 Query: 640 PA--PSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPV 697 P PS GPQ P PF P P+ S + +A A P Sbjct: 584 PCSHPSPSQGPQ---------------GAPYPFPPVPTVTTSSATLSTVIATVASSPAGY 628 Query: 698 STTDASPQSPPTPQTTLTPLQESPVISKDQSPP---PSPPPSYHPPPPPTKKPEVVVEAP 754 T ASP PP P P SP K +PP P PPS+ PP + +P Sbjct: 629 KT--ASPPGPP-PYGKRAP---SPGAYKTATPPGYKPGSPPSFRTGTPPGYRG----TSP 678 Query: 755 SASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSS 814 A +P P P PPA + PPP PA P+ P L Sbjct: 679 PAGPGTFKPGSPTVGPGPLPPAGPS---GLPSLPPP-----------PAAPASGPPL--- 721 Query: 815 PAASSSSATALQIQPPGSPDPPPAPPAPAP-ASSAPGHVAK 854 A A + + P SP PP P+P P P H ++ Sbjct: 722 SATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHASQ 762 >gi|55750041 atrophin-1 [Homo sapiens] Length = 1190 Score = 100 bits (249), Expect = 8e-21 Identities = 180/714 (25%), Positives = 236/714 (33%), Gaps = 153/714 (21%) Query: 453 PP--PQGG---SGRGSPSGGSTAEASDT-LSIRSSGQLSGRSVSLRKLKRPPPPPRRTHS 506 PP P+GG S G P+GG T +S+ SSG PP + + Sbjct: 231 PPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGA-------------PPTKPPT 277 Query: 507 LHQRGLAVPDGPLGLPPKPERKQQPQLPRPPT-------TGGSEGAGAAPCPPNPANSWV 559 G +P P PP P LP PP + G GA P P + + Sbjct: 278 TPVGGGNLPSAP---PPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHA 334 Query: 560 PGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSL 619 G GG P PE+ PTL P + PPAS PP +S Sbjct: 335 MGQGMGGL---PPGPEKG-------------PTLAPSPHSLPPASSSAPAPPMRFPYSSS 378 Query: 620 RSPGASVSSSLTSLCSSSSDPAPSDR---SGPQILTPLGDRFVIPPHPKVPAPFSPPPS- 675 S A+ SSS +S SSS+ P P+ + S P P V PK P P + Sbjct: 379 SSSSAAASSS-SSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAV 437 Query: 676 ---KPRSPNPAAPALAAPAVVPGPV-STTDASPQSPPTPQTTLTPLQESPVISKDQSPPP 731 P P P LA PGP +T A + P T Q+ + Q Sbjct: 438 WSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQ 497 Query: 732 SPPPSYH---PPPPPTKKPEVVVEAPS--ASETAEEPLQDPNWPPPPPPAPEEQDLSMAD 786 +H PPPP P + S A A P P PP P A Sbjct: 498 QQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGP---------AH 548 Query: 787 FPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAP-- 844 PPP S S AGP+G P SS ++SS+S + P P P P P Sbjct: 549 LPPPH----SQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPV 604 Query: 845 -----------------ASSAPGHVAKLPQKEP--------VGCSKGGGPPREDVGAPLV 879 ASS G+ P P G K PP G+P Sbjct: 605 PTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSP-- 662 Query: 880 TPSLLQMV--RLRSVGAPG-------GAPTPALGPSAPQKPLRRALSGRASPVPAPSSGL 930 PS R P G+PT GP P P L P AP+SG Sbjct: 663 -PSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGP--SGLPSLPPPPAAPASGP 719 Query: 931 H-AAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSP 989 +A ++K +E + + PP P PP S L+R + Sbjct: 720 PLSATQIKQ---EPAEEYETPESPVPPARSPSPPPKVVDVPSHASQSARFNKHLDRGFNS 776 Query: 990 ETQADL-------------QRNLVAELRSISEQRPPQAPKKSPKAPPPVARK-------- 1028 ++DL + +LV ++R +EQR + ++ + R+ Sbjct: 777 CARSDLYFVPLEGSKLAKKRADLVEKVRREAEQRAREEKEREREREREKEREREKERELE 836 Query: 1029 ---------------PSVGVPPPASPSYPRAEPLTAPPTNGLPHTQDRTKRELA 1067 PS+G P P P + T PP G RT E A Sbjct: 837 RSVKLAQEGRAPVECPSLGPVPHRPPFEPGSAVATVPPYLGPDTPALRTLSEYA 890 Score = 96.7 bits (239), Expect = 1e-19 Identities = 180/764 (23%), Positives = 257/764 (33%), Gaps = 149/764 (19%) Query: 373 SLRTLSRCSLHSASPASVRSLGRFSSVSSPQPRSRHPSSSSDTWSH----SQSSDTIVSD 428 S +T + + AS V GR +S + + + T SD D Sbjct: 50 SRQTAKKARVEEASTPKVNKQGRSEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLD 109 Query: 429 GSTLSSKGGSEGQP---ESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLS 485 G +L+ G S+ + ++ + S S+ P GS SD+ S S G Sbjct: 110 GRSLNDDGSSDPRDIDQDNRSTSPSIYSP------------GSVENDSDSSSGLSQGPAR 157 Query: 486 GRSVSLRKLKRPPPP---PRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLP--RPPT-- 538 P PP PR+ + + +V P +P + Q P PP Sbjct: 158 PYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHP 217 Query: 539 ---TGGSEGAGAAPCPPNP----ANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTP 591 GG+ G + P P P A S V G + G PP +P S + + + P Sbjct: 218 QLYPGGTGGVLSGP-PMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPP 276 Query: 592 TLPPKG----LAGPPASPGKAQP--PKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDR 645 T P G A PPA+ P P P + L + AS + P P Sbjct: 277 TTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGL-------GAQPLPGHL 329 Query: 646 SGPQILTP-LGDRFVIPPHPK-----VPAPFSPPPSKPRSPNP-------AAPALAAPAV 692 P + +G +PP P+ P+P S PP+ +P P ++ + +A A Sbjct: 330 PSPHAMGQGMGG---LPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAAS 386 Query: 693 VPGPVSTTDASP----QSPPT------PQTTLTPLQESPVISKDQSP--------PPSPP 734 S++ ASP Q+ P+ P T+L+ + P ++ P PP PP Sbjct: 387 SSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPP 446 Query: 735 P--------SYHPPP-PPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMA 785 P + HP P PP+ + P ++ Q ++Q Sbjct: 447 PYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGN 506 Query: 786 DFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPA 845 PPP AF P P G + P A S S +L+ PPG PP P + Sbjct: 507 SGPPPPGAF-----PHPL--EGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPP--PHSQVS 557 Query: 846 SSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGP 905 S G P PV S P PS Q P GAP P Sbjct: 558 YSQAG-----PNGPPVSSSSNSSSSTSQGSYPCSHPSPSQ--------GPQGAPYPF--- 601 Query: 906 SAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQS 965 PVP ++ + A ++ G +A P GPP R P Sbjct: 602 ---------------PPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAP-- 644 Query: 966 PASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPV 1025 S G+ K P + + R S PP P P V Sbjct: 645 ---------SPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTS---PPAGPGTFKPGSPTV 692 Query: 1026 ARKPSVGVPPPASPS-YPRAEPLTAPPTNGLPHTQDRTKRELAE 1068 P PPA PS P P A P +G P + + K+E AE Sbjct: 693 GPGPL----PPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAE 732 Score = 86.7 bits (213), Expect = 1e-16 Identities = 209/881 (23%), Positives = 290/881 (32%), Gaps = 172/881 (19%) Query: 23 RRKKSRSGASGLRRAFSWLRGKRRKKKAAGAEGAEPAAP--RAKKAEDKAKRAKGKGRGS 80 + K S S SG ++ R + R + A G ++ +A+K+ AK+A+ + + Sbjct: 5 QNKDSMSMRSGRKKEAPGPREELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVEEAST 64 Query: 81 AKAENDKHLSVGPGQGPGSAVDEHQ-DNVFFPSGRPPHLEELHTQAQEGLRSLQHQEKQK 139 K QG + E + + P E Q+ L SL + + Sbjct: 65 PKVNK---------QGRSEEISESESEETNAPKKTKTEQELPRPQSPSDLDSL---DGRS 112 Query: 140 LNKGGWDHGDTQSIQSSRTGPDEDNISFCSQTTSYVAESSTAEDALSIRSEMIQRKGSTF 199 LN G D + I D+DN S T+ + + E+ S + Q + Sbjct: 113 LNDDG--SSDPRDI-------DQDNRS----TSPSIYSPGSVENDSDSSSGLSQGPARPY 159 Query: 200 RPHDSFPKSGK---SGRRRRER----RSTVLGLPQHVQKELGLRNEREAP-GTPRA---- 247 P FP S + S R+ E +V H E +AP G P Sbjct: 160 HPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQL 219 Query: 248 -PGARDAVRIPTVDGRPRGTSGMGARVSLQALEAEAEAGAETEAMLQRHIDRVYRDDTFV 306 PG V + G P G G GA S+ Sbjct: 220 YPGGTGGV----LSGPPMGPKGGGAASSVG------------------------------ 245 Query: 307 GRSTGTRAPPLTRPMSLAVPGLTGGAGPAEPLSPA----MSISPQATYLSKLIPHAVLPP 362 G + G + PP T P+S++ G +G P +P + +P + P+ PP Sbjct: 246 GPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPP 305 Query: 363 TVDVVALGRCSLRTLSRCSL--HSASP-ASVRSLGRF------SSVSSPQPRSRHPSSSS 413 + + S L L H SP A + +G +P P S P+SSS Sbjct: 306 ALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSS 365 Query: 414 D-------TWSHSQSSDTIVSDGSTLSSKGGSEGQPESSTAS-NSVVPPPQGGSGRGSPS 465 +S S SS S S+ SS S + S PPP S P Sbjct: 366 APAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPP 425 Query: 466 GGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKP 525 T + + ++ S G PPPPP + R LA + G P P Sbjct: 426 -KYTQPSLPSQAVWSQGP-------------PPPPP------YGRLLANSNAHPG-PFPP 464 Query: 526 ERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYS 585 Q P +T G+ PP P P G S Sbjct: 465 STGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPP-PPGAFPHPLEGGS 523 Query: 586 SQSGTP-TLPPKGLAGPPASPGKAQPPKPERVTSL-----RSPGASVSSSLTSLCSSSSD 639 S P + P + P PG A P P S P S SS+ +S S S Sbjct: 524 SHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSY 583 Query: 640 PA--PSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPV 697 P PS GPQ P PF P P+ S + +A A P Sbjct: 584 PCSHPSPSQGPQ---------------GAPYPFPPVPTVTTSSATLSTVIATVASSPAGY 628 Query: 698 STTDASPQSPPTPQTTLTPLQESPVISKDQSPP---PSPPPSYHPPPPPTKKPEVVVEAP 754 T ASP PP P P SP K +PP P PPS+ PP + +P Sbjct: 629 KT--ASPPGPP-PYGKRAP---SPGAYKTATPPGYKPGSPPSFRTGTPPGYRG----TSP 678 Query: 755 SASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSS 814 A +P P P PPA + PPP PA P+ P L Sbjct: 679 PAGPGTFKPGSPTVGPGPLPPAGPS---GLPSLPPP-----------PAAPASGPPL--- 721 Query: 815 PAASSSSATALQIQPPGSPDPPPAPPAPAP-ASSAPGHVAK 854 A A + + P SP PP P+P P P H ++ Sbjct: 722 SATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHASQ 762 >gi|122937496 WAS/WASL interacting protein family, member 3 [Homo sapiens] Length = 483 Score = 100 bits (249), Expect = 8e-21 Identities = 122/435 (28%), Positives = 160/435 (36%), Gaps = 93/435 (21%) Query: 497 PPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAG-AAPCPPNPA 555 PPPPP L P PLG PP P P + ++ G +A Sbjct: 6 PPPPP----------LPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQ 55 Query: 556 NSWVPGLSPGGSRRPPR--SPERTLSPSSGYSSQSGTPTLPPKG--LAG--PPASP---- 605 + + ++ R P+ S + T G ++ G T P G AG P P Sbjct: 56 GTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQR 115 Query: 606 ----GKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIP 661 GK R S R P ++S L P S R G G P Sbjct: 116 DVAGGKTGQGPGSRAPSPRLPNKTISGPLI--------PPASPRLG-NTSEAHGAARTAP 166 Query: 662 PHPKVPAPFSPPPSKPRSPNPAAPALAAPAVV-------PGPVSTTD----------ASP 704 P P VPAP PPP+ P P P P L + + + PGP++ + A P Sbjct: 167 PRPNVPAP--PPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPP 224 Query: 705 QSPPTPQTTLTPLQESPVIS-KDQSP-------PPSPPPSYHPPPPPTKKPEVVVEAPSA 756 PP P T PL + V+S K P PP PPP P PP P + E S Sbjct: 225 PPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPL--PLLPPCGYPGLKAEPASP 282 Query: 757 SETAEEPLQDPNWPPPPPPAPEEQDLS-MADFP-PPEEAFFSVASPEPAGPSGSPELVSS 814 ++ A+EP P PPPP P S A P PP S + P P SP + Sbjct: 283 AQDAQEP------PAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAP 336 Query: 815 PAASSSSATALQIQPPGSP------------------DPPPAPPAPAP----ASSAPGHV 852 P + + A PPGS +PPPAPPA +P +S + Sbjct: 337 PQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSPTTELSSKSQQAT 396 Query: 853 AKLPQKEPVGCSKGG 867 A P ++P G + G Sbjct: 397 AWTPTQQPGGQLRNG 411 Score = 77.8 bits (190), Expect = 5e-14 Identities = 118/456 (25%), Positives = 147/456 (32%), Gaps = 100/456 (21%) Query: 591 PTLPPKGLAGPPASPGKAQPPKPER------VTSLRSPGASVSSSLTSLCSSSSD----P 640 P PP L PP G PP P +SLR S+L + + Sbjct: 4 PPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRKVT 63 Query: 641 APSDRSGPQI-----------------------------------LTPLGDRFVI----- 660 +DRS PQI L P G R V Sbjct: 64 QINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAGGKTG 123 Query: 661 -PPHPKVPAPFSP---------PPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTP 710 P + P+P P PP+ PR N + AA P P P PP P Sbjct: 124 QGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPP 183 Query: 711 QTTLTPLQESPVISKDQSPPPSP----------------PPSYHPPPPPTKKPEVVVEAP 754 PL S I PP P PP PPPPPT P + A Sbjct: 184 PPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPP--LPPAS 241 Query: 755 SASETAEEPLQDP-NWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVS 813 S+ A +P P + PP PPP P + A PA P P S Sbjct: 242 VLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYAS 301 Query: 814 SPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPRED 873 +S A L S PPP PP +P+ AP PQK G PP Sbjct: 302 CSPRASLPAPPLPGVNSSSETPPPLPP-KSPSFQAP------PQK--AGAQALPAPP--- 349 Query: 874 VGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAA 933 AP + LQ R GA GG P P+ P + LS ++ A + Sbjct: 350 --APPGSQPFLQKKRHGRPGAGGGKLNPP--PAPPARSPTTELSSKSQQATAWTPTQQPG 405 Query: 934 VRLKACSLAASEGLSS-----AQPNGPPEAEPRPPQ 964 +L+ SL + S + + PP E +P Q Sbjct: 406 GQLRNGSLHIIDDFESKFTFHSVEDFPPPDEYKPCQ 441 Score = 70.5 bits (171), Expect = 8e-12 Identities = 104/391 (26%), Positives = 135/391 (34%), Gaps = 95/391 (24%) Query: 426 VSDGSTLSSKGGSEGQPE--SSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQ 483 V+ G T G P + T S ++PP SP G+T+EA + R++ Sbjct: 117 VAGGKTGQGPGSRAPSPRLPNKTISGPLIPP-------ASPRLGNTSEAHG--AARTAPP 167 Query: 484 LSGRSVSLRKLKRPPPPPRR----THSLHQRGLAVPDGPLG-------LPPKPERKQQPQ 532 PPPPP + S + L P GPL PP P P Sbjct: 168 RPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPP 227 Query: 533 LPRPPTTGGSEGAGAAPCPPNPANS---WVPGLSPGGSRRPPRSPERTLSPSSGYSSQSG 589 P PPT P PP S P L+P PP P L P GY Sbjct: 228 PPPPPTP--------PPLPPASVLSDKAVKPQLAP--LHLPPIPPPLPLLPPCGYPGLKA 277 Query: 590 TPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQ 649 P P + PPA P PP P + SP AS+ + +SSS+ Sbjct: 278 EPASPAQDAQEPPAPP----PPLPPYASC--SPRASLPAPPLPGVNSSSE---------- 321 Query: 650 ILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPT 709 +PPP P+SP+ AP A A A P +PP Sbjct: 322 ---------------------TPPPLPPKSPSFQAPPQKAGA---------QALP-APPA 350 Query: 710 PQTTLTPLQESPVISKDQSPPPSPPPSYHPPP-PPTKKPEVVVEAPSASETAEEPLQDPN 768 P + LQ+ K P + +PPP PP + P + + S TA P Q P Sbjct: 351 PPGSQPFLQK-----KRHGRPGAGGGKLNPPPAPPARSPTTELSSKSQQATAWTPTQQPG 405 Query: 769 WPPPPPPAPEEQDL-------SMADFPPPEE 792 D S+ DFPPP+E Sbjct: 406 GQLRNGSLHIIDDFESKFTFHSVEDFPPPDE 436 Score = 62.0 bits (149), Expect = 3e-09 Identities = 98/411 (23%), Positives = 130/411 (31%), Gaps = 61/411 (14%) Query: 660 IPPHPKVPAPFSPPP-SKPRSPNPAAPALAAPAVVPGPVSTTDASPQ--SPPTPQTTLTP 716 +PP P P P PPP P P P+AP PVST +S + P L Sbjct: 3 VPPPPPPPLPPPPPPLGAPPPPPPSAP----------PVSTDTSSLRRADPKGRSALLAD 52 Query: 717 LQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPA 776 +Q+ + K P K+ AS P PA Sbjct: 53 IQQGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPA 112 Query: 777 PEEQDLSMADFPPPEEAFFSVASPE-----PAGPSGSPELVSSPAASSSSATA-----LQ 826 + P S P P P SP L ++ A ++ TA + Sbjct: 113 GQRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVP 172 Query: 827 IQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQM 886 PP +P PPP P P SS+P K P P G G P P P Sbjct: 173 APPPPTPPPPPPPLPPPLPSSSP---IKTPLVSPPGPLTKGNLPVVAPPVPCAPPP---- 225 Query: 887 VRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRA-SPVPAPSSGLHAAVRLKACSLAASE 945 P P P+ P P LS +A P AP L Sbjct: 226 ------------PPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYP 273 Query: 946 GLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRS 1005 GL A+P P + PP P + + S + L P P + Sbjct: 274 GLK-AEPASPAQDAQEPPAPPPPLPPY--ASCSPRASLPAPPLPGVNS------------ 318 Query: 1006 ISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEPLTAPPTNGLP 1056 S + PP P KSP P + + +P P +P P ++P +G P Sbjct: 319 -SSETPPPLPPKSPSFQAPPQKAGAQALPAPPAP--PGSQPFLQKKRHGRP 366 Score = 48.5 bits (114), Expect = 3e-05 Identities = 54/224 (24%), Positives = 74/224 (33%), Gaps = 22/224 (9%) Query: 829 PPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVR 888 P P PPP PP P P + P P PV + G + + Q R Sbjct: 2 PVPPPPPPPLPPPPPPLGAPP---PPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTR 58 Query: 889 LRSVGAPGGAPTPALGPS-APQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGL 947 LR V P + S K + + R + P P+ G A A + Sbjct: 59 LRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTP-PTLGDLFAGGFPVLRPAGQRDV 117 Query: 948 SSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSIS 1007 + + P + P+ P T S L P SP + +E + Sbjct: 118 AGGKTGQGPGSRAPSPRLPNKTISG---------PLIPPASP------RLGNTSEAHGAA 162 Query: 1008 EQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEPLTAPP 1051 PP+ P PPP P +PPP S P PL +PP Sbjct: 163 RTAPPR--PNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPP 204 Score = 39.7 bits (91), Expect = 0.016 Identities = 51/193 (26%), Positives = 64/193 (33%), Gaps = 34/193 (17%) Query: 515 PDGPLGLPPKPERKQQPQLPRPPTTG-GSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRS 573 P P LPP + LP PP G S P PP + P G P Sbjct: 290 PAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALP--- 346 Query: 574 PERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSL 633 +P + SQ P L K P A GK PP P S ++ L+S Sbjct: 347 -----APPAPPGSQ---PFLQKKRHGRPGAGGGKLNPPP-------APPARSPTTELSSK 391 Query: 634 CSSSSDPAPSDRSGPQ-------ILTPLGDRFVI-------PPHPKVPAPFSPPPSKPRS 679 ++ P+ + G Q I+ +F PP P P PRS Sbjct: 392 SQQATAWTPTQQPGGQLRNGSLHIIDDFESKFTFHSVEDFPPPDEYKPCQKIYPSKIPRS 451 Query: 680 PNPAAPALAAPAV 692 P P L A AV Sbjct: 452 RTP-GPWLQAEAV 463 >gi|153792074 proline rich 12 [Homo sapiens] Length = 2036 Score = 100 bits (249), Expect = 8e-21 Identities = 154/643 (23%), Positives = 218/643 (33%), Gaps = 92/643 (14%) Query: 461 RGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAV----PD 516 +G GG T E T + L+K PPPP ++ GL + PD Sbjct: 730 KGPERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQPTPHGLLLEAGGPD 789 Query: 517 GPLGLPPKPERKQQPQLPRPPTTGGS--------------EGAGAAPCPPNPANSWVP-- 560 PL LPP P + L P+ S +GA P PP P +P Sbjct: 790 LPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQ 849 Query: 561 --------GLSPGGSRRPPRSPERTLSPSSGYSSQSGT----PTLPPKGLAGPPASPGKA 608 GL P P PE +L P G P P GPP S GK Sbjct: 850 LEAHLRSHGLEPAAPS-PRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGK- 907 Query: 609 QPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPA 668 P R S + A LTS+C S +RS + + + K Sbjct: 908 DPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKA-- 965 Query: 669 PFSPPPSKPRSPNPAAPALAAPAVVP-GPVSTTDASPQSPPTPQTTLTPLQESPVISKDQ 727 PP + A P PA P GP AS P TP L P + + S Sbjct: 966 --GPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVN 1023 Query: 728 SPP------------PSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPN------W 769 + P P PPP PPP P +P+ + +P T + L + Sbjct: 1024 AEPLGLIQSGPHQAAPPPPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRR 1083 Query: 770 PPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQP 829 PP P++ +F E+ V + P P+LVSS + + + P Sbjct: 1084 RDPPFQTPKKLYAQEYEFEADEDK-ADVPADIRLNPRRLPDLVSSCRSRPA------LSP 1136 Query: 830 PGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRL 889 G D P P P P + P K +K GPPR G P + P + + Sbjct: 1137 LGDIDFCP----PNPGPDGPRRRGRKPTK-----AKRDGPPRPR-GRPRIRP-----LEV 1181 Query: 890 RSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSS 949 + P A TP G P + R +A +++K A EGL + Sbjct: 1182 PTTAGPASASTPTDGAKKP-RGRGRGRGRKAEEAGGTRLEPLKPLKIKLSVPKAGEGLGT 1240 Query: 950 AQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQ 1009 + + + S S K K++ PE ++ + + L+S ++ Sbjct: 1241 SSGDAISGTDHNSLDS-----SLTREKIEAKIKEVEEKQPEMKSGFMASFLDFLKS-GKR 1294 Query: 1010 RPP------QAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEP 1046 PP P PK+ PP + PPA+P+ P P Sbjct: 1295 HPPLYQAGLTPPLSPPKSVPPSVPARGLQPQPPATPAVPHPPP 1337 Score = 79.0 bits (193), Expect = 2e-14 Identities = 164/676 (24%), Positives = 234/676 (34%), Gaps = 122/676 (18%) Query: 455 PQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPPPPR------------ 502 P+ G G G+ SG + + +D S+ SS +++++ P + Sbjct: 1232 PKAGEGLGTSSGDAIS-GTDHNSLDSSLTREKIEAKIKEVEEKQPEMKSGFMASFLDFLK 1290 Query: 503 ---RTHSLHQRGLAVP-DGPLGLPPK-PERKQQPQ------LPRPPTTGGSEGAGAAPCP 551 R L+Q GL P P +PP P R QPQ +P PP +G GA Sbjct: 1291 SGKRHPPLYQAGLTPPLSPPKSVPPSVPARGLQPQPPATPAVPHPPPSGAFGLGGALEA- 1349 Query: 552 PNPANSWVPGLS-PGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQP 610 A S GL P +R +R L +SS Sbjct: 1350 ---AESEGLGLGCPSPCKRLDEELKRNLETLPSFSSD----------------------- 1383 Query: 611 PKPERVTSLRSPGASVSSSLTSLCSSSSDP---APSDRSGPQILTPLGDRFVIPPHPKVP 667 + + V R S+SS++++L DP P D S P PL +P P +P Sbjct: 1384 -EEDSVAKNRDLQESISSAISAL----DDPPLAGPKDTSTPDG-PPLAPAAAVPGPPPLP 1437 Query: 668 APFSPPPSKPRSPNPAAPALAA-PAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKD 726 PS + P P L P P P T P PP P P V Sbjct: 1438 GL----PSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTP 1493 Query: 727 QSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMAD 786 SPPP P P PPPPP P+A+ A P + P P P+ + L +A Sbjct: 1494 SSPPPPPLP---PPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLA- 1549 Query: 787 FPPPEEAFFSVASPEPAGPSGSPELVSSP---AASSSSATALQIQPPGSPDPPPAPPAPA 843 E A + E AG SG + + +L++ +PPP Sbjct: 1550 -KKQETAAVCGETDEEAGESGGEGIFRERDEFVIRAEDIPSLKLALQTGREPPPIWRVQK 1608 Query: 844 PASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPAL 903 K Q++ S G G L + L +V A Sbjct: 1609 ALLQKFTPEIKDGQRQFCATSNYLG----YFGDAKNRYQRLYVKFLENVNKKDYVRVCAR 1664 Query: 904 GP-SAPQKPLRRALSGRA-SPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPR 961 P P P+RR SG+A +PV S G SSA P P A P Sbjct: 1665 KPWHRPPVPVRR--SGQAKNPV--------------------SAGGSSAPPPKAP-APPP 1701 Query: 962 PPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKA 1021 P++P T S + + + + P +PE + L+ V + + + + P + +A Sbjct: 1702 KPETPEKTTSEKPPEQTPETAMPEPPAPEKPSLLRP--VEKEKEKEKVTRGERPLRGERA 1759 Query: 1022 PPPVARKP--SVGVPPPASPSYPRAEPL---TAPPTNGLPHTQDRTKRELAENGGVLQLV 1076 +P S+ PA+ P+A P PP + K+ L E GG Sbjct: 1760 TSGRQTRPERSLATGQPATSRLPKARPTKVKAEPPPK-------KRKKWLKEAGGNATAG 1812 Query: 1077 GPEEKMGLPGSDSQKE 1092 G G PGS S E Sbjct: 1813 G-----GPPGSSSDSE 1823 Score = 70.1 bits (170), Expect = 1e-11 Identities = 208/892 (23%), Positives = 266/892 (29%), Gaps = 258/892 (28%) Query: 312 TRAPPLTRPMSLAVPGLTGGAGPAEPL-----SPAMSISPQATYLSKLIPHAVLPPTVDV 366 TR PP P S A P GPA S A QA S P +L P Sbjct: 404 TRPPP---PRSTATPKCQSLGGPAAAYATGKASGAGGAGGQA--YSPGQPQGLLGPQAYG 458 Query: 367 VALGRCSLRTLSRCSLHSASPASVRSLGRFSSVSSPQPRSRHPSSSSDTWSHSQSSDTIV 426 G + LS+ +S P PQP S P T S S D + Sbjct: 459 QGFGGGQAQDLSKAPSYSGGP--------------PQPPSGPPPPGLAT-CQSYSPDQLQ 503 Query: 427 SD----------GSTLSSKGGSEGQPESS--TASNSVVPPPQGGSGRGSPSGGSTAEASD 474 G S+G P S T + + GG G S GG A S Sbjct: 504 GQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTGHSPALSGHGGGWGPSSLGGGGEASPSH 563 Query: 475 TLSIRSSGQLSGRSVSLRKLKRP--------------PPPPRRTHSLHQRG--------- 511 + S +GR + P PP +++ G Sbjct: 564 IIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGDGSE 623 Query: 512 -LAVPDGPLGLPPKPER---KQQPQLPRPPTTGGSEGA----GAAPCPPNPANSWVPGLS 563 LA P GP + E + Q P PP T G++G GAA GL Sbjct: 624 LLAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDGAADASK--------GLG 675 Query: 564 PGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPER--VTSLRS 621 G G GPP +P + P+R + S+ Sbjct: 676 GSG------------------------------GAGGPPGTPYELAKEDPQRYHLQSVIR 705 Query: 622 PGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPN 681 AS+ T+ + GP+ Sbjct: 706 TSASLDEGATAALELGLGRLKEKKKGPE---------------------------RGGET 738 Query: 682 PAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPP 741 P A + G +SPP P T Q +P ++ P P PPP Sbjct: 739 PEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVL-PPP 797 Query: 742 PPTKKPEVVVEAPSASETA--------EEPLQD--PNWPPPPPPAPEEQDLSMADFPPPE 791 PP P V+ APS S +A E +D P PPPPPP P L + Sbjct: 798 PPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQL------- 850 Query: 792 EAFFSVASPEPAGPSGS---PELVSSPAASSSSATALQIQPPGSPDPPPAPPA-----PA 843 EA EPA PS E + P A AL+ PP D PP PA Sbjct: 851 EAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPA 910 Query: 844 PASSAPG-HVAKLPQKEPVGC---------------------SKGGGP--------PRED 873 A +P K P+ P+ GGG P ED Sbjct: 911 GAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPED 970 Query: 874 VGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPV----PAPSSG 929 G P G P G P A P P P R + +G +P P Sbjct: 971 EGDPKA-----------GAGPPPGPP--AYDPYGPYCPGRASGAGPETPGLGLDPNKPPE 1017 Query: 930 LHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPAS------TASFIFSKGSRKLQ- 982 L + V + L S +A P PP P PP +PAS T+ S +KL Sbjct: 1018 LPSTVNAEPLGLIQSGPHQAAPPPPPP---PPPPPAPASEPKGGLTSPIFCSTKPKKLLK 1074 Query: 983 ------LERPVSP-----------------ETQADLQRNL------VAELRSISEQRPPQ 1013 L R P E +AD+ ++ + +L S RP Sbjct: 1075 TSSFHLLRRRDPPFQTPKKLYAQEYEFEADEDKADVPADIRLNPRRLPDLVSSCRSRPAL 1134 Query: 1014 AP---------KKSPKAPPPVARKPSVGVP--PPASPSYPRAEPLTAPPTNG 1054 +P P P RKP+ PP PR PL P T G Sbjct: 1135 SPLGDIDFCPPNPGPDGPRRRGRKPTKAKRDGPPRPRGRPRIRPLEVPTTAG 1186 Score = 65.1 bits (157), Expect = 4e-10 Identities = 193/819 (23%), Positives = 257/819 (31%), Gaps = 135/819 (16%) Query: 384 SASP-ASVRSLGRFSSVSSPQPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQP 442 SA P ASV +L PQP S S S S + + L G G Sbjct: 81 SAGPDASVMNLISALESRGPQPGPSASSLLSQFRSPSWQTAMHTPGPTELFISGALPGSS 140 Query: 443 E--SSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPPP 500 SS+A ++ P GS R P S + S ++G LS V K + P Sbjct: 141 TFPSSSALSAYQHPASFGS-RPFPVPSSLSLQDPPFSPPANGLLSPHDVLHLKPSQAPTV 199 Query: 501 PRRTHSLHQRGLAVPDGPLGLPPK---PERKQQPQLPRPPT---------TGGSEGA--- 545 P G V GP GL P P R P P PP S A Sbjct: 200 PSSLGFERLAGGGVL-GPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAA 258 Query: 546 -----------GAAPCPPNPANSWVPGLS--------PGGSRRPPRSP-----ERTLSPS 581 GAAP PP P + +P P ++ PP P + LS Sbjct: 259 EQSSPQLYNFSGAAPGPPPPERA-LPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCG 317 Query: 582 SGYSSQSGTPTLPPKGLAGPPASPGKAQPPK--PERVTSLRSPGASVSSSLTSLCSSSSD 639 Y S L L G SPG +P K P T+ GAS ++ Sbjct: 318 GSYPSMGHRANLACSPLGGGEPSPGAGEPSKAGPSGATA----GASGRATGPEAAGGGGA 373 Query: 640 PAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVST 699 P I +P G + + + PP + P +L PA Sbjct: 374 GGGGGGYRPIIQSP-GYKTGKGGYGAAAGGATRPPPPRSTATPKCQSLGGPAAAYATGKA 432 Query: 700 TDA-----SPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYH--PPPPPT--KKPEVV 750 + A SP PQ L P Q+ S PSY PP PP+ P + Sbjct: 433 SGAGGAGGQAYSPGQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLA 492 Query: 751 VEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSG--S 808 + + + L P P PA Q L A P ++ + SP +G G Sbjct: 493 TCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTAS---PSLSYSTGHSPALSGHGGGWG 549 Query: 809 PELVSSPAASSSSATALQIQPPGSPDPPPAPPAP-APASSAPGHVAKLPQKEPVGCS--- 864 P + +S S +Q P + PP +P AP +A P P G Sbjct: 550 PSSLGGGGEASPSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSYA 609 Query: 865 ------KG-----------GGPPREDV-GAPLVTPSLLQMV------------------- 887 KG GGPP E + LLQ Sbjct: 610 AGAGGYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDGAAD 669 Query: 888 RLRSVGAPGGAPTPALGP--SAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASE 945 + +G GGA P P A + P R L + G AA+ L Sbjct: 670 ASKGLGGSGGAGGPPGTPYELAKEDPQRYHLQSVIRTSASLDEGATAALEL-------GL 722 Query: 946 GLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRK----LQLERPVSPETQADLQ---RN 998 G + GP P +T+ + G+++ LQ P P T Q Sbjct: 723 GRLKEKKKGPERGGETP--EGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQPTPHG 780 Query: 999 LVAE-----LRSISEQRPPQ-APKKSPKAPPPVARKPSVGV---PPPASPSYPRAEPLTA 1049 L+ E L + PPQ P AP P VGV P P+ P Sbjct: 781 LLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPP 840 Query: 1050 PPTNGLP-HTQDRTKRELAENGGVLQLVGPEEKMGLPGS 1087 PP +P + + E + PEE + PG+ Sbjct: 841 PPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGA 879 Score = 60.8 bits (146), Expect = 7e-09 Identities = 131/596 (21%), Positives = 184/596 (30%), Gaps = 124/596 (20%) Query: 315 PPLTRPMSLAVPGLTGGAGPAEPLSPAMSISPQATYLSKLIPHAVLPPTVDVVALGRCSL 374 PPL+ P S+ G P P +PA +PH PP LG Sbjct: 1305 PPLSPPKSVPPSVPARGLQPQPPATPA-------------VPH---PPPSGAFGLG---- 1344 Query: 375 RTLSRCSLHSASPASVRSLGRFSSVSSPQPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSS 434 + A LG + P P R + + ++ + SD + Sbjct: 1345 --------GALEAAESEGLG----LGCPSPCKR---LDEELKRNLETLPSFSSDEEDSVA 1389 Query: 435 KGGSEGQPESSTASNSVVPPPQGGSGRGSPSGGSTAEAS------DTLSIRSSGQLSGRS 488 K + SS S PP G +P G A A+ + S+ Sbjct: 1390 KNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPE 1449 Query: 489 VSLRKLKRPP-PPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAGA 547 L + K PP PPP T P PP P QP LP PP Sbjct: 1450 PPLLEEKPPPTPPPAPT-------------PQPQPPPPPPPPQPALPSPPPL-------V 1489 Query: 548 APCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGK 607 AP P +P +P P PP P +P LA PP P Sbjct: 1490 APTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAP-----------------LAAPPEEPAA 1532 Query: 608 AQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIP----PH 663 P PE + R + ++C + + A SG + + D FVI P Sbjct: 1533 PSPEDPE-LPDTRPLHLAKKQETAAVCGETDEEA--GESGGEGIFRERDEFVIRAEDIPS 1589 Query: 664 PKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDAS------PQSPPTPQTTLTPL 717 K+ P A P + G S + Q Sbjct: 1590 LKLALQTGREPPPIWRVQKALLQKFTPEIKDGQRQFCATSNYLGYFGDAKNRYQRLYVKF 1649 Query: 718 QESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAP 777 E+ V KD + P +H PP P ++ SA ++ P + P PPP P Sbjct: 1650 LEN-VNKKDYVRVCARKP-WHRPPVPVRRSGQAKNPVSAGGSSAPPPK----APAPPPKP 1703 Query: 778 EEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELV---------------SSPAASSSSA 822 E + + ++ PP + A PEP P P L+ P + Sbjct: 1704 ETPEKTTSEKPPEQTP--ETAMPEPPAPE-KPSLLRPVEKEKEKEKVTRGERPLRGERAT 1760 Query: 823 TALQIQP--------PGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPP 870 + Q +P P + P A P A P K ++ + GGGPP Sbjct: 1761 SGRQTRPERSLATGQPATSRLPKARPTKVKAEPPPKKRKKWLKEAGGNATAGGGPP 1816 Score = 50.1 bits (118), Expect = 1e-05 Identities = 128/551 (23%), Positives = 181/551 (32%), Gaps = 90/551 (16%) Query: 453 PPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPP-PPPRRTHSLHQRG 511 PPP + P GG T+ S + L S L + + PP P++ ++ Sbjct: 1044 PPPPPPAPASEPKGGLTSPIF--CSTKPKKLLKTSSFHLLRRRDPPFQTPKKLYAQEYEF 1101 Query: 512 LAVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAGAAP------CPPNPANSWVPGLSPG 565 A D P R +LP ++ S A +P CPPNP P Sbjct: 1102 EA--DEDKADVPADIRLNPRRLPDLVSSCRSRPA-LSPLGDIDFCPPNPG--------PD 1150 Query: 566 GSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPP-----KPE-----R 615 G RR R P T + G G P + P + A P A P KP R Sbjct: 1151 GPRRRGRKP--TKAKRDGPPRPRGRPRIRPLEVP-TTAGPASASTPTDGAKKPRGRGRGR 1207 Query: 616 VTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPP- 674 G + L L S P ++G + T GD H + + + Sbjct: 1208 GRKAEEAGGTRLEPLKPLKIKLSVP----KAGEGLGTSSGDAISGTDHNSLDSSLTREKI 1263 Query: 675 -SKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSP---- 729 +K + P + + + + + + PP Q LTP P P Sbjct: 1264 EAKIKEVEEKQPEMKS-GFMASFLDFLKSGKRHPPLYQAGLTPPLSPPKSVPPSVPARGL 1322 Query: 730 ---PPSPPPSYHPPPPPTKKPEVVVEA----------PSASETAEEPLQDPNWPPPPPPA 776 PP+ P HPPP +EA PS + +E L+ N P + Sbjct: 1323 QPQPPATPAVPHPPPSGAFGLGGALEAAESEGLGLGCPSPCKRLDEELKR-NLETLPSFS 1381 Query: 777 PEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPP 836 +E+D S+A +E+ S S P P+ S+P + A P PP Sbjct: 1382 SDEED-SVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAA------AVPGPP 1434 Query: 837 PAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGP-PREDVGAPLVTPSLLQMVRLRSVGAP 895 P P P+ S+ L +K P P P+ P P+L P Sbjct: 1435 PLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSP-------PP 1487 Query: 896 GGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGP 955 APTP+ P P P P P P+ A LA A P P Sbjct: 1488 LVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPA----------AAPLA-------APPEEP 1530 Query: 956 PEAEPRPPQSP 966 P P+ P Sbjct: 1531 AAPSPEDPELP 1541 Score = 42.4 bits (98), Expect = 0.002 Identities = 54/238 (22%), Positives = 83/238 (34%), Gaps = 33/238 (13%) Query: 478 IRSSGQLS------GRSVSLRKLKRPPP------------PPRRTHSLHQRGLAVPDGPL 519 +R SGQ G S K PPP PP +T P+ P Sbjct: 1674 VRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPEKPS 1733 Query: 520 GLPPKPERKQQPQLPRP--PTTGGSEGAGAAPCPPN------PANSWVPGLSPGGSRR-- 569 L P + K++ ++ R P G +G P PA S +P P + Sbjct: 1734 LLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLPKARPTKVKAEP 1793 Query: 570 PPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSS 629 PP+ ++ L + G ++ G P P +P + + P R+ R+ S Sbjct: 1794 PPKKRKKWLKEAGGNATAGGGPPGSSSDSESSPGAPSEDERAVPGRLLKTRAMREMYRSY 1853 Query: 630 LTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPAL 687 + L S++ DP Q L D +PP K+ + K +PAL Sbjct: 1854 VEMLVSTALDP-----DMIQALEDTHDELYLPPMRKIDGLLNEHKKKVLKRLSLSPAL 1906 Score = 36.6 bits (83), Expect = 0.13 Identities = 46/189 (24%), Positives = 64/189 (33%), Gaps = 22/189 (11%) Query: 672 PPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPP 731 PP RS P A + P P +P PP P+T P + + PP Sbjct: 1670 PPVPVRRSGQAKNPVSAGGSSAPPP-----KAPAPPPKPET--------PEKTTSEKPPE 1716 Query: 732 SPPPSYHPPPPPTKKPEVV--VEAPSASE---TAEEPLQDPNWPPPPPPAPEEQDLSMAD 786 P + P PP +KP ++ VE E E PL+ PE S+A Sbjct: 1717 QTPETAMPEPPAPEKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPER---SLAT 1773 Query: 787 FPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPAS 846 P + + + +ATA P S D +P AP+ Sbjct: 1774 GQPATSRLPKARPTKVKAEPPPKKRKKWLKEAGGNATAGGGPPGSSSDSESSPGAPSEDE 1833 Query: 847 SA-PGHVAK 854 A PG + K Sbjct: 1834 RAVPGRLLK 1842 Score = 33.9 bits (76), Expect = 0.86 Identities = 39/175 (22%), Positives = 57/175 (32%), Gaps = 45/175 (25%) Query: 640 PAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVST 699 P P RSG Q P+ P PK PAP P P P P P T Sbjct: 1671 PVPVRRSG-QAKNPVSAGGSSAPPPKAPAP-PPKPETPEKTTSEKP----------PEQT 1718 Query: 700 TDASPQSPPTPQ--TTLTPLQ---ESPVISKDQSP------------------------- 729 + + PP P+ + L P++ E +++ + P Sbjct: 1719 PETAMPEPPAPEKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPAT 1778 Query: 730 ---PPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQD 781 P + P PPP K+ + + EA + P + P AP E + Sbjct: 1779 SRLPKARPTKVKAEPPPKKRKKWLKEAGGNATAGGGPPGSSSDSESSPGAPSEDE 1833 Score = 30.8 bits (68), Expect = 7.3 Identities = 21/68 (30%), Positives = 30/68 (44%), Gaps = 2/68 (2%) Query: 15 PGNPGGPPRRKKSRSGASGLRRAFSWLRGKRRKKKAAGAEGAEPAAPRAKKAEDKAKRAK 74 P NPG R++ R R RG+ R + A PA+ A D AK+ + Sbjct: 1144 PPNPGPDGPRRRGRKPTKAKRDGPPRPRGRPRIRPLEVPTTAGPAS--ASTPTDGAKKPR 1201 Query: 75 GKGRGSAK 82 G+GRG + Sbjct: 1202 GRGRGRGR 1209 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.307 0.127 0.376 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 67,541,965 Number of Sequences: 37866 Number of extensions: 5285100 Number of successful extensions: 113619 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 1103 Number of HSP's successfully gapped in prelim test: 3122 Number of HSP's that attempted gapping in prelim test: 28044 Number of HSP's gapped (non-prelim): 37822 length of query: 1094 length of database: 18,247,518 effective HSP length: 113 effective length of query: 981 effective length of database: 13,968,660 effective search space: 13703255460 effective search space used: 13703255460 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.6 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.