Guide to the Human Genome
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Search of human proteins with 169207592

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169207592 PREDICTED: zinc finger homeobox 2 [Homo sapiens]
         (2706 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169207592 PREDICTED: zinc finger homeobox 2 [Homo sapiens]        5604   0.0  
gi|169207014 PREDICTED: zinc finger homeobox 2 [Homo sapiens]        5604   0.0  
gi|169207217 PREDICTED: zinc finger homeobox 2 [Homo sapiens]        5598   0.0  
gi|118498345 AT-binding transcription factor 1 [Homo sapiens]         531   e-150
gi|126090663 zinc finger homeodomain 4 [Homo sapiens]                 500   e-141
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]         78   1e-13
gi|153792074 proline rich 12 [Homo sapiens]                            75   7e-13
gi|50083287 LIM homeobox 8 [Homo sapiens]                              73   3e-12
gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Ho...    73   4e-12
gi|152963644 paired-like homeodomain transcription factor 1 [Hom...    70   3e-11
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    69   5e-11
gi|134284361 LIM homeobox protein 6 isoform 2 [Homo sapiens]           69   6e-11
gi|134284359 LIM homeobox protein 6 isoform 1 [Homo sapiens]           69   6e-11
gi|4505007 LIM homeobox transcription factor 1, beta [Homo sapiens]    68   1e-10
gi|122937321 UNC homeobox [Homo sapiens]                               68   1e-10
gi|33569216 LIM homeobox 9 isoform 1 [Homo sapiens]                    68   1e-10
gi|62241033 LIM homeobox 9 isoform 2 [Homo sapiens]                    68   1e-10
gi|47132519 Ras association and pleckstrin homology domains 1 is...    67   2e-10
gi|12707580 paired-like homeobox 2b [Homo sapiens]                     66   4e-10
gi|169881277 PROP paired-like homeobox 1 [Homo sapiens]                66   5e-10
gi|156416026 zinc finger protein 219 [Homo sapiens]                    65   7e-10
gi|156415998 zinc finger protein 219 [Homo sapiens]                    65   7e-10
gi|156415996 zinc finger protein 219 [Homo sapiens]                    65   7e-10
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    65   1e-09
gi|148277064 cut-like homeobox 1 isoform a [Homo sapiens]              64   2e-09
gi|30023847 LIM homeobox protein 3 isoform a [Homo sapiens]            64   2e-09
gi|7657303 LIM homeobox protein 3 isoform b [Homo sapiens]             64   2e-09
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    63   3e-09
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    63   4e-09
gi|24497589 aristaless related homeobox [Homo sapiens]                 63   4e-09

>gi|169207592 PREDICTED: zinc finger homeobox 2 [Homo sapiens]
          Length = 2706

 Score = 5604 bits (14538), Expect = 0.0
 Identities = 2706/2706 (100%), Positives = 2706/2706 (100%)

Query: 1    MATLNSASTTGTTPSPGHNAPSLPSDTFSSSTPSDPVTKDPPAASSTSENMRSSEPGGQL 60
            MATLNSASTTGTTPSPGHNAPSLPSDTFSSSTPSDPVTKDPPAASSTSENMRSSEPGGQL
Sbjct: 1    MATLNSASTTGTTPSPGHNAPSLPSDTFSSSTPSDPVTKDPPAASSTSENMRSSEPGGQL 60

Query: 61   LESGCGLVPPKEIGEPQEGPDCGHFPPNDPGVEKDKEQEEEEEGLPPMDLSNHLFFTAGG 120
            LESGCGLVPPKEIGEPQEGPDCGHFPPNDPGVEKDKEQEEEEEGLPPMDLSNHLFFTAGG
Sbjct: 61   LESGCGLVPPKEIGEPQEGPDCGHFPPNDPGVEKDKEQEEEEEGLPPMDLSNHLFFTAGG 120

Query: 121  EAYLVAKLSLPGGSELLLPKGFPWGEAGIKEEPSLPFLAYPPPSHLTALHIQHGFDPIQG 180
            EAYLVAKLSLPGGSELLLPKGFPWGEAGIKEEPSLPFLAYPPPSHLTALHIQHGFDPIQG
Sbjct: 121  EAYLVAKLSLPGGSELLLPKGFPWGEAGIKEEPSLPFLAYPPPSHLTALHIQHGFDPIQG 180

Query: 181  FSSSDQILSHDTSAPSPAACEERHGAFWSYQLAPNPPGDPKDGPMGNSGGNHVAVFWLCL 240
            FSSSDQILSHDTSAPSPAACEERHGAFWSYQLAPNPPGDPKDGPMGNSGGNHVAVFWLCL
Sbjct: 181  FSSSDQILSHDTSAPSPAACEERHGAFWSYQLAPNPPGDPKDGPMGNSGGNHVAVFWLCL 240

Query: 241  LCRLGFSKPQAFMDHTQSHGVKLTPAQYQGLSGSPAVLQEGDEGCKALISFLEPKLPARP 300
            LCRLGFSKPQAFMDHTQSHGVKLTPAQYQGLSGSPAVLQEGDEGCKALISFLEPKLPARP
Sbjct: 241  LCRLGFSKPQAFMDHTQSHGVKLTPAQYQGLSGSPAVLQEGDEGCKALISFLEPKLPARP 300

Query: 301  SSDIPLDNSSTVNMEANVAQTEDGPPEAEVQALILLDEEVMALSPPSPPTATWDPSPTQA 360
            SSDIPLDNSSTVNMEANVAQTEDGPPEAEVQALILLDEEVMALSPPSPPTATWDPSPTQA
Sbjct: 301  SSDIPLDNSSTVNMEANVAQTEDGPPEAEVQALILLDEEVMALSPPSPPTATWDPSPTQA 360

Query: 361  KESPVAAGEAGPDWFPEGQEEDGGLCPPLNQSSPTSKEGGTLPAPVGSPEDPSDPPQPYR 420
            KESPVAAGEAGPDWFPEGQEEDGGLCPPLNQSSPTSKEGGTLPAPVGSPEDPSDPPQPYR
Sbjct: 361  KESPVAAGEAGPDWFPEGQEEDGGLCPPLNQSSPTSKEGGTLPAPVGSPEDPSDPPQPYR 420

Query: 421  LADDYTPAPAAFQGLSLSSHMSLLHSRNSCKTLKCPKCNWHYKYQQTLDVHMREKHPESN 480
            LADDYTPAPAAFQGLSLSSHMSLLHSRNSCKTLKCPKCNWHYKYQQTLDVHMREKHPESN
Sbjct: 421  LADDYTPAPAAFQGLSLSSHMSLLHSRNSCKTLKCPKCNWHYKYQQTLDVHMREKHPESN 480

Query: 481  SHCSYCSAGGAHPRLARGESYNCGYKPYRCDVCNYSTTTKGNLSIHMQSDKHLANLQGFQ 540
            SHCSYCSAGGAHPRLARGESYNCGYKPYRCDVCNYSTTTKGNLSIHMQSDKHLANLQGFQ
Sbjct: 481  SHCSYCSAGGAHPRLARGESYNCGYKPYRCDVCNYSTTTKGNLSIHMQSDKHLANLQGFQ 540

Query: 541  AGPGGQGSPPEASLPPSAGDKEPKTKSSWQCKVCSYETNISRNLRIHMTSEKHMQNVLML 600
            AGPGGQGSPPEASLPPSAGDKEPKTKSSWQCKVCSYETNISRNLRIHMTSEKHMQNVLML
Sbjct: 541  AGPGGQGSPPEASLPPSAGDKEPKTKSSWQCKVCSYETNISRNLRIHMTSEKHMQNVLML 600

Query: 601  HQGLPLGLPPGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRPDKPLEA 660
            HQGLPLGLPPGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRPDKPLEA
Sbjct: 601  HQGLPLGLPPGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRPDKPLEA 660

Query: 661  QLLLNGFHHVGAPARKFPTSAPGSLSPDAHLPPSQLLGSSSDSLPTSPPPDDSLSLKVFR 720
            QLLLNGFHHVGAPARKFPTSAPGSLSPDAHLPPSQLLGSSSDSLPTSPPPDDSLSLKVFR
Sbjct: 661  QLLLNGFHHVGAPARKFPTSAPGSLSPDAHLPPSQLLGSSSDSLPTSPPPDDSLSLKVFR 720

Query: 721  CLVCQAFSTDSLELLLYHCSIGRSLPEAEWKEVAGDTHRCKLCCYGTQLKANFQLHLKTD 780
            CLVCQAFSTDSLELLLYHCSIGRSLPEAEWKEVAGDTHRCKLCCYGTQLKANFQLHLKTD
Sbjct: 721  CLVCQAFSTDSLELLLYHCSIGRSLPEAEWKEVAGDTHRCKLCCYGTQLKANFQLHLKTD 780

Query: 781  KHAQKYQLAAHLREGGGAMGTPSPASLGDGAPYGSVSPLHLRCNICDFESNSKEKMQLHA 840
            KHAQKYQLAAHLREGGGAMGTPSPASLGDGAPYGSVSPLHLRCNICDFESNSKEKMQLHA
Sbjct: 781  KHAQKYQLAAHLREGGGAMGTPSPASLGDGAPYGSVSPLHLRCNICDFESNSKEKMQLHA 840

Query: 841  RGAAHEENSQIYKVRLGAELGLYHCLLCAWETPSRLAVLQHLRTPAHRDAQAQRRLQLLQ 900
            RGAAHEENSQIYKVRLGAELGLYHCLLCAWETPSRLAVLQHLRTPAHRDAQAQRRLQLLQ
Sbjct: 841  RGAAHEENSQIYKVRLGAELGLYHCLLCAWETPSRLAVLQHLRTPAHRDAQAQRRLQLLQ 900

Query: 901  NGPTTEEGLAALQSILSFSHGQLRTPAEVVPAEAGNSQPGTIDPEGTGEEPARGCQRLHL 960
            NGPTTEEGLAALQSILSFSHGQLRTPAEVVPAEAGNSQPGTIDPEGTGEEPARGCQRLHL
Sbjct: 901  NGPTTEEGLAALQSILSFSHGQLRTPAEVVPAEAGNSQPGTIDPEGTGEEPARGCQRLHL 960

Query: 961  KKKKKKKKEWGRASAASKGLCDGGSHPSLTLRPLPICSLQVYCCPYCSFLSPESSQVRAH 1020
            KKKKKKKKEWGRASAASKGLCDGGSHPSLTLRPLPICSLQVYCCPYCSFLSPESSQVRAH
Sbjct: 961  KKKKKKKKEWGRASAASKGLCDGGSHPSLTLRPLPICSLQVYCCPYCSFLSPESSQVRAH 1020

Query: 1021 TLSQHAVQPKYRCPLCQEQLVGRPALHFHLSHLHNVVPECVEKLLLVVSTGWVRTVQQDL 1080
            TLSQHAVQPKYRCPLCQEQLVGRPALHFHLSHLHNVVPECVEKLLLVVSTGWVRTVQQDL
Sbjct: 1021 TLSQHAVQPKYRCPLCQEQLVGRPALHFHLSHLHNVVPECVEKLLLVVSTGWVRTVQQDL 1080

Query: 1081 IRAVQEGRKRQGYSGRCMCWGQGAFRQVRVLAGWVRSGIGAVGGGGEATRLFLIAGYNCR 1140
            IRAVQEGRKRQGYSGRCMCWGQGAFRQVRVLAGWVRSGIGAVGGGGEATRLFLIAGYNCR
Sbjct: 1081 IRAVQEGRKRQGYSGRCMCWGQGAFRQVRVLAGWVRSGIGAVGGGGEATRLFLIAGYNCR 1140

Query: 1141 NDIYNQSAVCTHIKPSGQWPRTPHSWARAYTEQRPGSRKGDSMGQQGLKMTEAKVNCLGI 1200
            NDIYNQSAVCTHIKPSGQWPRTPHSWARAYTEQRPGSRKGDSMGQQGLKMTEAKVNCLGI
Sbjct: 1141 NDIYNQSAVCTHIKPSGQWPRTPHSWARAYTEQRPGSRKGDSMGQQGLKMTEAKVNCLGI 1200

Query: 1201 EWVGSGLNEVPSSLYFLLSPLEGPNLTPEASPDPLPEPPLASVEVPDKPSGSPGQPPSPA 1260
            EWVGSGLNEVPSSLYFLLSPLEGPNLTPEASPDPLPEPPLASVEVPDKPSGSPGQPPSPA
Sbjct: 1201 EWVGSGLNEVPSSLYFLLSPLEGPNLTPEASPDPLPEPPLASVEVPDKPSGSPGQPPSPA 1260

Query: 1261 PSPVPEPDAQAEDVAPPPTMAEEEEGTTGELRSAEPAPADSRHPLTYRKTTNFALDKFLD 1320
            PSPVPEPDAQAEDVAPPPTMAEEEEGTTGELRSAEPAPADSRHPLTYRKTTNFALDKFLD
Sbjct: 1261 PSPVPEPDAQAEDVAPPPTMAEEEEGTTGELRSAEPAPADSRHPLTYRKTTNFALDKFLD 1320

Query: 1321 PARPYKCTVCKESFTQKNILLVHYNSVSHLHKMKKAAIDPSAPARGEAGAPPTTTAATDK 1380
            PARPYKCTVCKESFTQKNILLVHYNSVSHLHKMKKAAIDPSAPARGEAGAPPTTTAATDK
Sbjct: 1321 PARPYKCTVCKESFTQKNILLVHYNSVSHLHKMKKAAIDPSAPARGEAGAPPTTTAATDK 1380

Query: 1381 PFKCTVCRVSYNQSSTLEIHMRSVLHQTRSRGTKTDSKIEGPERSQEEPKEGETEGEVGT 1440
            PFKCTVCRVSYNQSSTLEIHMRSVLHQTRSRGTKTDSKIEGPERSQEEPKEGETEGEVGT
Sbjct: 1381 PFKCTVCRVSYNQSSTLEIHMRSVLHQTRSRGTKTDSKIEGPERSQEEPKEGETEGEVGT 1440

Query: 1441 EKKGPDTSGFISGLPFLSPPPPPLDLHRFPAPLFTPPVLPPFPLVPESLLKLQQQQLLLP 1500
            EKKGPDTSGFISGLPFLSPPPPPLDLHRFPAPLFTPPVLPPFPLVPESLLKLQQQQLLLP
Sbjct: 1441 EKKGPDTSGFISGLPFLSPPPPPLDLHRFPAPLFTPPVLPPFPLVPESLLKLQQQQLLLP 1500

Query: 1501 FYLHDLKVGPKLTLAGPAPVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPSS 1560
            FYLHDLKVGPKLTLAGPAPVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPSS
Sbjct: 1501 FYLHDLKVGPKLTLAGPAPVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPSS 1560

Query: 1561 PPDPLPNEAARTAAKALLENFGFELVIQYNEGKQAVPPPPTPPPPEALGGGDKLACGACG 1620
            PPDPLPNEAARTAAKALLENFGFELVIQYNEGKQAVPPPPTPPPPEALGGGDKLACGACG
Sbjct: 1561 PPDPLPNEAARTAAKALLENFGFELVIQYNEGKQAVPPPPTPPPPEALGGGDKLACGACG 1620

Query: 1621 KLFSNMLILKTHEEHVHRRFLPFEALSRYAAQFRKSYDSLYPPLAEPPKPPDGSLDSPVP 1680
            KLFSNMLILKTHEEHVHRRFLPFEALSRYAAQFRKSYDSLYPPLAEPPKPPDGSLDSPVP
Sbjct: 1621 KLFSNMLILKTHEEHVHRRFLPFEALSRYAAQFRKSYDSLYPPLAEPPKPPDGSLDSPVP 1680

Query: 1681 HLGPPFLVPEPEAGGTRAPEERSRAGGHWPIEEEESSRGNLPPLVPAGRRFSRTKFTEFQ 1740
            HLGPPFLVPEPEAGGTRAPEERSRAGGHWPIEEEESSRGNLPPLVPAGRRFSRTKFTEFQ
Sbjct: 1681 HLGPPFLVPEPEAGGTRAPEERSRAGGHWPIEEEESSRGNLPPLVPAGRRFSRTKFTEFQ 1740

Query: 1741 TQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARKNACEGGSMPTGGGT 1800
            TQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARKNACEGGSMPTGGGT
Sbjct: 1741 TQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARKNACEGGSMPTGGGT 1800

Query: 1801 GGASGCRRCHATFSCVFELVRHLKKCYDDQTLEEEEEEAERGEEEEEVEEEEVEEEQGLE 1860
            GGASGCRRCHATFSCVFELVRHLKKCYDDQTLEEEEEEAERGEEEEEVEEEEVEEEQGLE
Sbjct: 1801 GGASGCRRCHATFSCVFELVRHLKKCYDDQTLEEEEEEAERGEEEEEVEEEEVEEEQGLE 1860

Query: 1861 PPAGPEGPLPEPPDGEELSQAEATKAGGKEPEEKATPSPSPAHTCDQCAISFSSQDLLTS 1920
            PPAGPEGPLPEPPDGEELSQAEATKAGGKEPEEKATPSPSPAHTCDQCAISFSSQDLLTS
Sbjct: 1861 PPAGPEGPLPEPPDGEELSQAEATKAGGKEPEEKATPSPSPAHTCDQCAISFSSQDLLTS 1920

Query: 1921 HRRLHFLPSLQPSAPPQLLDLPLLVFGERNPLVAATSPMPGPPLKRKHEDGSLSPTGSEA 1980
            HRRLHFLPSLQPSAPPQLLDLPLLVFGERNPLVAATSPMPGPPLKRKHEDGSLSPTGSEA
Sbjct: 1921 HRRLHFLPSLQPSAPPQLLDLPLLVFGERNPLVAATSPMPGPPLKRKHEDGSLSPTGSEA 1980

Query: 1981 GGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQ 2040
            GGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQ
Sbjct: 1981 GGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQ 2040

Query: 2041 NTRARERKGQFRSTPGGVPSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAF 2100
            NTRARERKGQFRSTPGGVPSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAF
Sbjct: 2041 NTRARERKGQFRSTPGGVPSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAF 2100

Query: 2101 PYPTATLASGPQPFLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESEACSLS 2160
            PYPTATLASGPQPFLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESEACSLS
Sbjct: 2101 PYPTATLASGPQPFLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESEACSLS 2160

Query: 2161 AGDLSDSSASSLAEPESPGAGGTSGGPGGGTGVPDGMGQRRYRTQMSSLQLKIMKACYEA 2220
            AGDLSDSSASSLAEPESPGAGGTSGGPGGGTGVPDGMGQRRYRTQMSSLQLKIMKACYEA
Sbjct: 2161 AGDLSDSSASSLAEPESPGAGGTSGGPGGGTGVPDGMGQRRYRTQMSSLQLKIMKACYEA 2220

Query: 2221 YRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAKLQGTAAGSTGGSSEGLLAAQRT 2280
            YRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAKLQGTAAGSTGGSSEGLLAAQRT
Sbjct: 2221 YRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAKLQGTAAGSTGGSSEGLLAAQRT 2280

Query: 2281 DCPYCDVKYDFYVSCRGHLFSRQHLAKLKEAVRAQLKSESKCYDLAPAPEAPPALKAPPA 2340
            DCPYCDVKYDFYVSCRGHLFSRQHLAKLKEAVRAQLKSESKCYDLAPAPEAPPALKAPPA
Sbjct: 2281 DCPYCDVKYDFYVSCRGHLFSRQHLAKLKEAVRAQLKSESKCYDLAPAPEAPPALKAPPA 2340

Query: 2341 TTPASMPLGAAPTLPRLAPVLLSGPALAQPPLGNLAPFNSGPAASSGLLGLATSVLPTTT 2400
            TTPASMPLGAAPTLPRLAPVLLSGPALAQPPLGNLAPFNSGPAASSGLLGLATSVLPTTT
Sbjct: 2341 TTPASMPLGAAPTLPRLAPVLLSGPALAQPPLGNLAPFNSGPAASSGLLGLATSVLPTTT 2400

Query: 2401 VVQTAGPGRPLPQRPMPDQTNTSTAGTTDPVPGPPTEPLGDKVSSERKPVAGPTSSSNDA 2460
            VVQTAGPGRPLPQRPMPDQTNTSTAGTTDPVPGPPTEPLGDKVSSERKPVAGPTSSSNDA
Sbjct: 2401 VVQTAGPGRPLPQRPMPDQTNTSTAGTTDPVPGPPTEPLGDKVSSERKPVAGPTSSSNDA 2460

Query: 2461 LKNLKALKTTVPALLGGQFLPFPLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNP 2520
            LKNLKALKTTVPALLGGQFLPFPLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNP
Sbjct: 2461 LKNLKALKTTVPALLGGQFLPFPLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNP 2520

Query: 2521 MIPQTLIGLLPNALLQPPPQPPEPTATAPPKPPELPAPGEGEAGEVDELLTGSTGISTVD 2580
            MIPQTLIGLLPNALLQPPPQPPEPTATAPPKPPELPAPGEGEAGEVDELLTGSTGISTVD
Sbjct: 2521 MIPQTLIGLLPNALLQPPPQPPEPTATAPPKPPELPAPGEGEAGEVDELLTGSTGISTVD 2580

Query: 2581 VTHRYLCRQCKMAFDGEAPATAHQRSFCFFGRGSGGSMPPPLRVPICTYHCLACEVLLSG 2640
            VTHRYLCRQCKMAFDGEAPATAHQRSFCFFGRGSGGSMPPPLRVPICTYHCLACEVLLSG
Sbjct: 2581 VTHRYLCRQCKMAFDGEAPATAHQRSFCFFGRGSGGSMPPPLRVPICTYHCLACEVLLSG 2640

Query: 2641 REALASHLRSSAHRRKAAPPQGGPPISITNAATAASAAVAFAKEEARLPHTDSNPKTTTT 2700
            REALASHLRSSAHRRKAAPPQGGPPISITNAATAASAAVAFAKEEARLPHTDSNPKTTTT
Sbjct: 2641 REALASHLRSSAHRRKAAPPQGGPPISITNAATAASAAVAFAKEEARLPHTDSNPKTTTT 2700

Query: 2701 STLLAL 2706
            STLLAL
Sbjct: 2701 STLLAL 2706


>gi|169207014 PREDICTED: zinc finger homeobox 2 [Homo sapiens]
          Length = 2706

 Score = 5604 bits (14538), Expect = 0.0
 Identities = 2706/2706 (100%), Positives = 2706/2706 (100%)

Query: 1    MATLNSASTTGTTPSPGHNAPSLPSDTFSSSTPSDPVTKDPPAASSTSENMRSSEPGGQL 60
            MATLNSASTTGTTPSPGHNAPSLPSDTFSSSTPSDPVTKDPPAASSTSENMRSSEPGGQL
Sbjct: 1    MATLNSASTTGTTPSPGHNAPSLPSDTFSSSTPSDPVTKDPPAASSTSENMRSSEPGGQL 60

Query: 61   LESGCGLVPPKEIGEPQEGPDCGHFPPNDPGVEKDKEQEEEEEGLPPMDLSNHLFFTAGG 120
            LESGCGLVPPKEIGEPQEGPDCGHFPPNDPGVEKDKEQEEEEEGLPPMDLSNHLFFTAGG
Sbjct: 61   LESGCGLVPPKEIGEPQEGPDCGHFPPNDPGVEKDKEQEEEEEGLPPMDLSNHLFFTAGG 120

Query: 121  EAYLVAKLSLPGGSELLLPKGFPWGEAGIKEEPSLPFLAYPPPSHLTALHIQHGFDPIQG 180
            EAYLVAKLSLPGGSELLLPKGFPWGEAGIKEEPSLPFLAYPPPSHLTALHIQHGFDPIQG
Sbjct: 121  EAYLVAKLSLPGGSELLLPKGFPWGEAGIKEEPSLPFLAYPPPSHLTALHIQHGFDPIQG 180

Query: 181  FSSSDQILSHDTSAPSPAACEERHGAFWSYQLAPNPPGDPKDGPMGNSGGNHVAVFWLCL 240
            FSSSDQILSHDTSAPSPAACEERHGAFWSYQLAPNPPGDPKDGPMGNSGGNHVAVFWLCL
Sbjct: 181  FSSSDQILSHDTSAPSPAACEERHGAFWSYQLAPNPPGDPKDGPMGNSGGNHVAVFWLCL 240

Query: 241  LCRLGFSKPQAFMDHTQSHGVKLTPAQYQGLSGSPAVLQEGDEGCKALISFLEPKLPARP 300
            LCRLGFSKPQAFMDHTQSHGVKLTPAQYQGLSGSPAVLQEGDEGCKALISFLEPKLPARP
Sbjct: 241  LCRLGFSKPQAFMDHTQSHGVKLTPAQYQGLSGSPAVLQEGDEGCKALISFLEPKLPARP 300

Query: 301  SSDIPLDNSSTVNMEANVAQTEDGPPEAEVQALILLDEEVMALSPPSPPTATWDPSPTQA 360
            SSDIPLDNSSTVNMEANVAQTEDGPPEAEVQALILLDEEVMALSPPSPPTATWDPSPTQA
Sbjct: 301  SSDIPLDNSSTVNMEANVAQTEDGPPEAEVQALILLDEEVMALSPPSPPTATWDPSPTQA 360

Query: 361  KESPVAAGEAGPDWFPEGQEEDGGLCPPLNQSSPTSKEGGTLPAPVGSPEDPSDPPQPYR 420
            KESPVAAGEAGPDWFPEGQEEDGGLCPPLNQSSPTSKEGGTLPAPVGSPEDPSDPPQPYR
Sbjct: 361  KESPVAAGEAGPDWFPEGQEEDGGLCPPLNQSSPTSKEGGTLPAPVGSPEDPSDPPQPYR 420

Query: 421  LADDYTPAPAAFQGLSLSSHMSLLHSRNSCKTLKCPKCNWHYKYQQTLDVHMREKHPESN 480
            LADDYTPAPAAFQGLSLSSHMSLLHSRNSCKTLKCPKCNWHYKYQQTLDVHMREKHPESN
Sbjct: 421  LADDYTPAPAAFQGLSLSSHMSLLHSRNSCKTLKCPKCNWHYKYQQTLDVHMREKHPESN 480

Query: 481  SHCSYCSAGGAHPRLARGESYNCGYKPYRCDVCNYSTTTKGNLSIHMQSDKHLANLQGFQ 540
            SHCSYCSAGGAHPRLARGESYNCGYKPYRCDVCNYSTTTKGNLSIHMQSDKHLANLQGFQ
Sbjct: 481  SHCSYCSAGGAHPRLARGESYNCGYKPYRCDVCNYSTTTKGNLSIHMQSDKHLANLQGFQ 540

Query: 541  AGPGGQGSPPEASLPPSAGDKEPKTKSSWQCKVCSYETNISRNLRIHMTSEKHMQNVLML 600
            AGPGGQGSPPEASLPPSAGDKEPKTKSSWQCKVCSYETNISRNLRIHMTSEKHMQNVLML
Sbjct: 541  AGPGGQGSPPEASLPPSAGDKEPKTKSSWQCKVCSYETNISRNLRIHMTSEKHMQNVLML 600

Query: 601  HQGLPLGLPPGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRPDKPLEA 660
            HQGLPLGLPPGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRPDKPLEA
Sbjct: 601  HQGLPLGLPPGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRPDKPLEA 660

Query: 661  QLLLNGFHHVGAPARKFPTSAPGSLSPDAHLPPSQLLGSSSDSLPTSPPPDDSLSLKVFR 720
            QLLLNGFHHVGAPARKFPTSAPGSLSPDAHLPPSQLLGSSSDSLPTSPPPDDSLSLKVFR
Sbjct: 661  QLLLNGFHHVGAPARKFPTSAPGSLSPDAHLPPSQLLGSSSDSLPTSPPPDDSLSLKVFR 720

Query: 721  CLVCQAFSTDSLELLLYHCSIGRSLPEAEWKEVAGDTHRCKLCCYGTQLKANFQLHLKTD 780
            CLVCQAFSTDSLELLLYHCSIGRSLPEAEWKEVAGDTHRCKLCCYGTQLKANFQLHLKTD
Sbjct: 721  CLVCQAFSTDSLELLLYHCSIGRSLPEAEWKEVAGDTHRCKLCCYGTQLKANFQLHLKTD 780

Query: 781  KHAQKYQLAAHLREGGGAMGTPSPASLGDGAPYGSVSPLHLRCNICDFESNSKEKMQLHA 840
            KHAQKYQLAAHLREGGGAMGTPSPASLGDGAPYGSVSPLHLRCNICDFESNSKEKMQLHA
Sbjct: 781  KHAQKYQLAAHLREGGGAMGTPSPASLGDGAPYGSVSPLHLRCNICDFESNSKEKMQLHA 840

Query: 841  RGAAHEENSQIYKVRLGAELGLYHCLLCAWETPSRLAVLQHLRTPAHRDAQAQRRLQLLQ 900
            RGAAHEENSQIYKVRLGAELGLYHCLLCAWETPSRLAVLQHLRTPAHRDAQAQRRLQLLQ
Sbjct: 841  RGAAHEENSQIYKVRLGAELGLYHCLLCAWETPSRLAVLQHLRTPAHRDAQAQRRLQLLQ 900

Query: 901  NGPTTEEGLAALQSILSFSHGQLRTPAEVVPAEAGNSQPGTIDPEGTGEEPARGCQRLHL 960
            NGPTTEEGLAALQSILSFSHGQLRTPAEVVPAEAGNSQPGTIDPEGTGEEPARGCQRLHL
Sbjct: 901  NGPTTEEGLAALQSILSFSHGQLRTPAEVVPAEAGNSQPGTIDPEGTGEEPARGCQRLHL 960

Query: 961  KKKKKKKKEWGRASAASKGLCDGGSHPSLTLRPLPICSLQVYCCPYCSFLSPESSQVRAH 1020
            KKKKKKKKEWGRASAASKGLCDGGSHPSLTLRPLPICSLQVYCCPYCSFLSPESSQVRAH
Sbjct: 961  KKKKKKKKEWGRASAASKGLCDGGSHPSLTLRPLPICSLQVYCCPYCSFLSPESSQVRAH 1020

Query: 1021 TLSQHAVQPKYRCPLCQEQLVGRPALHFHLSHLHNVVPECVEKLLLVVSTGWVRTVQQDL 1080
            TLSQHAVQPKYRCPLCQEQLVGRPALHFHLSHLHNVVPECVEKLLLVVSTGWVRTVQQDL
Sbjct: 1021 TLSQHAVQPKYRCPLCQEQLVGRPALHFHLSHLHNVVPECVEKLLLVVSTGWVRTVQQDL 1080

Query: 1081 IRAVQEGRKRQGYSGRCMCWGQGAFRQVRVLAGWVRSGIGAVGGGGEATRLFLIAGYNCR 1140
            IRAVQEGRKRQGYSGRCMCWGQGAFRQVRVLAGWVRSGIGAVGGGGEATRLFLIAGYNCR
Sbjct: 1081 IRAVQEGRKRQGYSGRCMCWGQGAFRQVRVLAGWVRSGIGAVGGGGEATRLFLIAGYNCR 1140

Query: 1141 NDIYNQSAVCTHIKPSGQWPRTPHSWARAYTEQRPGSRKGDSMGQQGLKMTEAKVNCLGI 1200
            NDIYNQSAVCTHIKPSGQWPRTPHSWARAYTEQRPGSRKGDSMGQQGLKMTEAKVNCLGI
Sbjct: 1141 NDIYNQSAVCTHIKPSGQWPRTPHSWARAYTEQRPGSRKGDSMGQQGLKMTEAKVNCLGI 1200

Query: 1201 EWVGSGLNEVPSSLYFLLSPLEGPNLTPEASPDPLPEPPLASVEVPDKPSGSPGQPPSPA 1260
            EWVGSGLNEVPSSLYFLLSPLEGPNLTPEASPDPLPEPPLASVEVPDKPSGSPGQPPSPA
Sbjct: 1201 EWVGSGLNEVPSSLYFLLSPLEGPNLTPEASPDPLPEPPLASVEVPDKPSGSPGQPPSPA 1260

Query: 1261 PSPVPEPDAQAEDVAPPPTMAEEEEGTTGELRSAEPAPADSRHPLTYRKTTNFALDKFLD 1320
            PSPVPEPDAQAEDVAPPPTMAEEEEGTTGELRSAEPAPADSRHPLTYRKTTNFALDKFLD
Sbjct: 1261 PSPVPEPDAQAEDVAPPPTMAEEEEGTTGELRSAEPAPADSRHPLTYRKTTNFALDKFLD 1320

Query: 1321 PARPYKCTVCKESFTQKNILLVHYNSVSHLHKMKKAAIDPSAPARGEAGAPPTTTAATDK 1380
            PARPYKCTVCKESFTQKNILLVHYNSVSHLHKMKKAAIDPSAPARGEAGAPPTTTAATDK
Sbjct: 1321 PARPYKCTVCKESFTQKNILLVHYNSVSHLHKMKKAAIDPSAPARGEAGAPPTTTAATDK 1380

Query: 1381 PFKCTVCRVSYNQSSTLEIHMRSVLHQTRSRGTKTDSKIEGPERSQEEPKEGETEGEVGT 1440
            PFKCTVCRVSYNQSSTLEIHMRSVLHQTRSRGTKTDSKIEGPERSQEEPKEGETEGEVGT
Sbjct: 1381 PFKCTVCRVSYNQSSTLEIHMRSVLHQTRSRGTKTDSKIEGPERSQEEPKEGETEGEVGT 1440

Query: 1441 EKKGPDTSGFISGLPFLSPPPPPLDLHRFPAPLFTPPVLPPFPLVPESLLKLQQQQLLLP 1500
            EKKGPDTSGFISGLPFLSPPPPPLDLHRFPAPLFTPPVLPPFPLVPESLLKLQQQQLLLP
Sbjct: 1441 EKKGPDTSGFISGLPFLSPPPPPLDLHRFPAPLFTPPVLPPFPLVPESLLKLQQQQLLLP 1500

Query: 1501 FYLHDLKVGPKLTLAGPAPVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPSS 1560
            FYLHDLKVGPKLTLAGPAPVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPSS
Sbjct: 1501 FYLHDLKVGPKLTLAGPAPVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPSS 1560

Query: 1561 PPDPLPNEAARTAAKALLENFGFELVIQYNEGKQAVPPPPTPPPPEALGGGDKLACGACG 1620
            PPDPLPNEAARTAAKALLENFGFELVIQYNEGKQAVPPPPTPPPPEALGGGDKLACGACG
Sbjct: 1561 PPDPLPNEAARTAAKALLENFGFELVIQYNEGKQAVPPPPTPPPPEALGGGDKLACGACG 1620

Query: 1621 KLFSNMLILKTHEEHVHRRFLPFEALSRYAAQFRKSYDSLYPPLAEPPKPPDGSLDSPVP 1680
            KLFSNMLILKTHEEHVHRRFLPFEALSRYAAQFRKSYDSLYPPLAEPPKPPDGSLDSPVP
Sbjct: 1621 KLFSNMLILKTHEEHVHRRFLPFEALSRYAAQFRKSYDSLYPPLAEPPKPPDGSLDSPVP 1680

Query: 1681 HLGPPFLVPEPEAGGTRAPEERSRAGGHWPIEEEESSRGNLPPLVPAGRRFSRTKFTEFQ 1740
            HLGPPFLVPEPEAGGTRAPEERSRAGGHWPIEEEESSRGNLPPLVPAGRRFSRTKFTEFQ
Sbjct: 1681 HLGPPFLVPEPEAGGTRAPEERSRAGGHWPIEEEESSRGNLPPLVPAGRRFSRTKFTEFQ 1740

Query: 1741 TQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARKNACEGGSMPTGGGT 1800
            TQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARKNACEGGSMPTGGGT
Sbjct: 1741 TQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARKNACEGGSMPTGGGT 1800

Query: 1801 GGASGCRRCHATFSCVFELVRHLKKCYDDQTLEEEEEEAERGEEEEEVEEEEVEEEQGLE 1860
            GGASGCRRCHATFSCVFELVRHLKKCYDDQTLEEEEEEAERGEEEEEVEEEEVEEEQGLE
Sbjct: 1801 GGASGCRRCHATFSCVFELVRHLKKCYDDQTLEEEEEEAERGEEEEEVEEEEVEEEQGLE 1860

Query: 1861 PPAGPEGPLPEPPDGEELSQAEATKAGGKEPEEKATPSPSPAHTCDQCAISFSSQDLLTS 1920
            PPAGPEGPLPEPPDGEELSQAEATKAGGKEPEEKATPSPSPAHTCDQCAISFSSQDLLTS
Sbjct: 1861 PPAGPEGPLPEPPDGEELSQAEATKAGGKEPEEKATPSPSPAHTCDQCAISFSSQDLLTS 1920

Query: 1921 HRRLHFLPSLQPSAPPQLLDLPLLVFGERNPLVAATSPMPGPPLKRKHEDGSLSPTGSEA 1980
            HRRLHFLPSLQPSAPPQLLDLPLLVFGERNPLVAATSPMPGPPLKRKHEDGSLSPTGSEA
Sbjct: 1921 HRRLHFLPSLQPSAPPQLLDLPLLVFGERNPLVAATSPMPGPPLKRKHEDGSLSPTGSEA 1980

Query: 1981 GGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQ 2040
            GGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQ
Sbjct: 1981 GGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQ 2040

Query: 2041 NTRARERKGQFRSTPGGVPSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAF 2100
            NTRARERKGQFRSTPGGVPSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAF
Sbjct: 2041 NTRARERKGQFRSTPGGVPSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAF 2100

Query: 2101 PYPTATLASGPQPFLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESEACSLS 2160
            PYPTATLASGPQPFLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESEACSLS
Sbjct: 2101 PYPTATLASGPQPFLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESEACSLS 2160

Query: 2161 AGDLSDSSASSLAEPESPGAGGTSGGPGGGTGVPDGMGQRRYRTQMSSLQLKIMKACYEA 2220
            AGDLSDSSASSLAEPESPGAGGTSGGPGGGTGVPDGMGQRRYRTQMSSLQLKIMKACYEA
Sbjct: 2161 AGDLSDSSASSLAEPESPGAGGTSGGPGGGTGVPDGMGQRRYRTQMSSLQLKIMKACYEA 2220

Query: 2221 YRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAKLQGTAAGSTGGSSEGLLAAQRT 2280
            YRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAKLQGTAAGSTGGSSEGLLAAQRT
Sbjct: 2221 YRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAKLQGTAAGSTGGSSEGLLAAQRT 2280

Query: 2281 DCPYCDVKYDFYVSCRGHLFSRQHLAKLKEAVRAQLKSESKCYDLAPAPEAPPALKAPPA 2340
            DCPYCDVKYDFYVSCRGHLFSRQHLAKLKEAVRAQLKSESKCYDLAPAPEAPPALKAPPA
Sbjct: 2281 DCPYCDVKYDFYVSCRGHLFSRQHLAKLKEAVRAQLKSESKCYDLAPAPEAPPALKAPPA 2340

Query: 2341 TTPASMPLGAAPTLPRLAPVLLSGPALAQPPLGNLAPFNSGPAASSGLLGLATSVLPTTT 2400
            TTPASMPLGAAPTLPRLAPVLLSGPALAQPPLGNLAPFNSGPAASSGLLGLATSVLPTTT
Sbjct: 2341 TTPASMPLGAAPTLPRLAPVLLSGPALAQPPLGNLAPFNSGPAASSGLLGLATSVLPTTT 2400

Query: 2401 VVQTAGPGRPLPQRPMPDQTNTSTAGTTDPVPGPPTEPLGDKVSSERKPVAGPTSSSNDA 2460
            VVQTAGPGRPLPQRPMPDQTNTSTAGTTDPVPGPPTEPLGDKVSSERKPVAGPTSSSNDA
Sbjct: 2401 VVQTAGPGRPLPQRPMPDQTNTSTAGTTDPVPGPPTEPLGDKVSSERKPVAGPTSSSNDA 2460

Query: 2461 LKNLKALKTTVPALLGGQFLPFPLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNP 2520
            LKNLKALKTTVPALLGGQFLPFPLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNP
Sbjct: 2461 LKNLKALKTTVPALLGGQFLPFPLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNP 2520

Query: 2521 MIPQTLIGLLPNALLQPPPQPPEPTATAPPKPPELPAPGEGEAGEVDELLTGSTGISTVD 2580
            MIPQTLIGLLPNALLQPPPQPPEPTATAPPKPPELPAPGEGEAGEVDELLTGSTGISTVD
Sbjct: 2521 MIPQTLIGLLPNALLQPPPQPPEPTATAPPKPPELPAPGEGEAGEVDELLTGSTGISTVD 2580

Query: 2581 VTHRYLCRQCKMAFDGEAPATAHQRSFCFFGRGSGGSMPPPLRVPICTYHCLACEVLLSG 2640
            VTHRYLCRQCKMAFDGEAPATAHQRSFCFFGRGSGGSMPPPLRVPICTYHCLACEVLLSG
Sbjct: 2581 VTHRYLCRQCKMAFDGEAPATAHQRSFCFFGRGSGGSMPPPLRVPICTYHCLACEVLLSG 2640

Query: 2641 REALASHLRSSAHRRKAAPPQGGPPISITNAATAASAAVAFAKEEARLPHTDSNPKTTTT 2700
            REALASHLRSSAHRRKAAPPQGGPPISITNAATAASAAVAFAKEEARLPHTDSNPKTTTT
Sbjct: 2641 REALASHLRSSAHRRKAAPPQGGPPISITNAATAASAAVAFAKEEARLPHTDSNPKTTTT 2700

Query: 2701 STLLAL 2706
            STLLAL
Sbjct: 2701 STLLAL 2706


>gi|169207217 PREDICTED: zinc finger homeobox 2 [Homo sapiens]
          Length = 2790

 Score = 5598 bits (14522), Expect = 0.0
 Identities = 2704/2706 (99%), Positives = 2704/2706 (99%)

Query: 1    MATLNSASTTGTTPSPGHNAPSLPSDTFSSSTPSDPVTKDPPAASSTSENMRSSEPGGQL 60
            MATLNSASTTGTTPSPGHNAPSLPSDTFSSSTPSD VTKDPPAASSTSENMRSSEPGGQL
Sbjct: 85   MATLNSASTTGTTPSPGHNAPSLPSDTFSSSTPSDSVTKDPPAASSTSENMRSSEPGGQL 144

Query: 61   LESGCGLVPPKEIGEPQEGPDCGHFPPNDPGVEKDKEQEEEEEGLPPMDLSNHLFFTAGG 120
            LESGCGLVPPKEIGEPQEGPDCGHFPPNDPGVEKDKEQEEEEEGLPPMDLSNHLFFTAGG
Sbjct: 145  LESGCGLVPPKEIGEPQEGPDCGHFPPNDPGVEKDKEQEEEEEGLPPMDLSNHLFFTAGG 204

Query: 121  EAYLVAKLSLPGGSELLLPKGFPWGEAGIKEEPSLPFLAYPPPSHLTALHIQHGFDPIQG 180
            EAYLVAKLSLPGGSELLLPKGFPWGEAGIKEEPSLPFLAYPPPSHLTALHIQHGFDPIQG
Sbjct: 205  EAYLVAKLSLPGGSELLLPKGFPWGEAGIKEEPSLPFLAYPPPSHLTALHIQHGFDPIQG 264

Query: 181  FSSSDQILSHDTSAPSPAACEERHGAFWSYQLAPNPPGDPKDGPMGNSGGNHVAVFWLCL 240
            FSSSDQILSHDTSAPSPAACEERHGAFWSYQLAPNPPGDPKDGPMGNSGGNHVAVFWLCL
Sbjct: 265  FSSSDQILSHDTSAPSPAACEERHGAFWSYQLAPNPPGDPKDGPMGNSGGNHVAVFWLCL 324

Query: 241  LCRLGFSKPQAFMDHTQSHGVKLTPAQYQGLSGSPAVLQEGDEGCKALISFLEPKLPARP 300
            LCRLGFSKPQAFMDHTQSHGVKLTPAQYQGLSGSPAVLQEGDEGCKALISFLEPKLPARP
Sbjct: 325  LCRLGFSKPQAFMDHTQSHGVKLTPAQYQGLSGSPAVLQEGDEGCKALISFLEPKLPARP 384

Query: 301  SSDIPLDNSSTVNMEANVAQTEDGPPEAEVQALILLDEEVMALSPPSPPTATWDPSPTQA 360
            SSDIPLDNSSTVNMEANVAQTEDGPPEAEVQALILLDEEVMALSPPSPPTATWDPSPTQA
Sbjct: 385  SSDIPLDNSSTVNMEANVAQTEDGPPEAEVQALILLDEEVMALSPPSPPTATWDPSPTQA 444

Query: 361  KESPVAAGEAGPDWFPEGQEEDGGLCPPLNQSSPTSKEGGTLPAPVGSPEDPSDPPQPYR 420
            KESPVAAGEAGPDWFPEGQEEDGGLCPPLNQSSPTSKEGGTLPAPVGSPEDPSDPPQPYR
Sbjct: 445  KESPVAAGEAGPDWFPEGQEEDGGLCPPLNQSSPTSKEGGTLPAPVGSPEDPSDPPQPYR 504

Query: 421  LADDYTPAPAAFQGLSLSSHMSLLHSRNSCKTLKCPKCNWHYKYQQTLDVHMREKHPESN 480
            LADDYTPAPAAFQGLSLSSHMSLLHSRNSCKTLKCPKCNWHYKYQQTLDVHMREKHPESN
Sbjct: 505  LADDYTPAPAAFQGLSLSSHMSLLHSRNSCKTLKCPKCNWHYKYQQTLDVHMREKHPESN 564

Query: 481  SHCSYCSAGGAHPRLARGESYNCGYKPYRCDVCNYSTTTKGNLSIHMQSDKHLANLQGFQ 540
            SHCSYCSAGGAHPRLARGESYNCGYKPYRCDVCNYSTTTKGNLSIHMQSDKHLANLQGFQ
Sbjct: 565  SHCSYCSAGGAHPRLARGESYNCGYKPYRCDVCNYSTTTKGNLSIHMQSDKHLANLQGFQ 624

Query: 541  AGPGGQGSPPEASLPPSAGDKEPKTKSSWQCKVCSYETNISRNLRIHMTSEKHMQNVLML 600
            AGPGGQGSP EASLPPSAGDKEPKTKSSWQCKVCSYETNISRNLRIHMTSEKHMQNVLML
Sbjct: 625  AGPGGQGSPTEASLPPSAGDKEPKTKSSWQCKVCSYETNISRNLRIHMTSEKHMQNVLML 684

Query: 601  HQGLPLGLPPGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRPDKPLEA 660
            HQGLPLGLPPGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRPDKPLEA
Sbjct: 685  HQGLPLGLPPGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRPDKPLEA 744

Query: 661  QLLLNGFHHVGAPARKFPTSAPGSLSPDAHLPPSQLLGSSSDSLPTSPPPDDSLSLKVFR 720
            QLLLNGFHHVGAPARKFPTSAPGSLSPDAHLPPSQLLGSSSDSLPTSPPPDDSLSLKVFR
Sbjct: 745  QLLLNGFHHVGAPARKFPTSAPGSLSPDAHLPPSQLLGSSSDSLPTSPPPDDSLSLKVFR 804

Query: 721  CLVCQAFSTDSLELLLYHCSIGRSLPEAEWKEVAGDTHRCKLCCYGTQLKANFQLHLKTD 780
            CLVCQAFSTDSLELLLYHCSIGRSLPEAEWKEVAGDTHRCKLCCYGTQLKANFQLHLKTD
Sbjct: 805  CLVCQAFSTDSLELLLYHCSIGRSLPEAEWKEVAGDTHRCKLCCYGTQLKANFQLHLKTD 864

Query: 781  KHAQKYQLAAHLREGGGAMGTPSPASLGDGAPYGSVSPLHLRCNICDFESNSKEKMQLHA 840
            KHAQKYQLAAHLREGGGAMGTPSPASLGDGAPYGSVSPLHLRCNICDFESNSKEKMQLHA
Sbjct: 865  KHAQKYQLAAHLREGGGAMGTPSPASLGDGAPYGSVSPLHLRCNICDFESNSKEKMQLHA 924

Query: 841  RGAAHEENSQIYKVRLGAELGLYHCLLCAWETPSRLAVLQHLRTPAHRDAQAQRRLQLLQ 900
            RGAAHEENSQIYKVRLGAELGLYHCLLCAWETPSRLAVLQHLRTPAHRDAQAQRRLQLLQ
Sbjct: 925  RGAAHEENSQIYKVRLGAELGLYHCLLCAWETPSRLAVLQHLRTPAHRDAQAQRRLQLLQ 984

Query: 901  NGPTTEEGLAALQSILSFSHGQLRTPAEVVPAEAGNSQPGTIDPEGTGEEPARGCQRLHL 960
            NGPTTEEGLAALQSILSFSHGQLRTPAEVVPAEAGNSQPGTIDPEGTGEEPARGCQRLHL
Sbjct: 985  NGPTTEEGLAALQSILSFSHGQLRTPAEVVPAEAGNSQPGTIDPEGTGEEPARGCQRLHL 1044

Query: 961  KKKKKKKKEWGRASAASKGLCDGGSHPSLTLRPLPICSLQVYCCPYCSFLSPESSQVRAH 1020
            KKKKKKKKEWGRASAASKGLCDGGSHPSLTLRPLPICSLQVYCCPYCSFLSPESSQVRAH
Sbjct: 1045 KKKKKKKKEWGRASAASKGLCDGGSHPSLTLRPLPICSLQVYCCPYCSFLSPESSQVRAH 1104

Query: 1021 TLSQHAVQPKYRCPLCQEQLVGRPALHFHLSHLHNVVPECVEKLLLVVSTGWVRTVQQDL 1080
            TLSQHAVQPKYRCPLCQEQLVGRPALHFHLSHLHNVVPECVEKLLLVVSTGWVRTVQQDL
Sbjct: 1105 TLSQHAVQPKYRCPLCQEQLVGRPALHFHLSHLHNVVPECVEKLLLVVSTGWVRTVQQDL 1164

Query: 1081 IRAVQEGRKRQGYSGRCMCWGQGAFRQVRVLAGWVRSGIGAVGGGGEATRLFLIAGYNCR 1140
            IRAVQEGRKRQGYSGRCMCWGQGAFRQVRVLAGWVRSGIGAVGGGGEATRLFLIAGYNCR
Sbjct: 1165 IRAVQEGRKRQGYSGRCMCWGQGAFRQVRVLAGWVRSGIGAVGGGGEATRLFLIAGYNCR 1224

Query: 1141 NDIYNQSAVCTHIKPSGQWPRTPHSWARAYTEQRPGSRKGDSMGQQGLKMTEAKVNCLGI 1200
            NDIYNQSAVCTHIKPSGQWPRTPHSWARAYTEQRPGSRKGDSMGQQGLKMTEAKVNCLGI
Sbjct: 1225 NDIYNQSAVCTHIKPSGQWPRTPHSWARAYTEQRPGSRKGDSMGQQGLKMTEAKVNCLGI 1284

Query: 1201 EWVGSGLNEVPSSLYFLLSPLEGPNLTPEASPDPLPEPPLASVEVPDKPSGSPGQPPSPA 1260
            EWVGSGLNEVPSSLYFLLSPLEGPNLTPEASPDPLPEPPLASVEVPDKPSGSPGQPPSPA
Sbjct: 1285 EWVGSGLNEVPSSLYFLLSPLEGPNLTPEASPDPLPEPPLASVEVPDKPSGSPGQPPSPA 1344

Query: 1261 PSPVPEPDAQAEDVAPPPTMAEEEEGTTGELRSAEPAPADSRHPLTYRKTTNFALDKFLD 1320
            PSPVPEPDAQAEDVAPPPTMAEEEEGTTGELRSAEPAPADSRHPLTYRKTTNFALDKFLD
Sbjct: 1345 PSPVPEPDAQAEDVAPPPTMAEEEEGTTGELRSAEPAPADSRHPLTYRKTTNFALDKFLD 1404

Query: 1321 PARPYKCTVCKESFTQKNILLVHYNSVSHLHKMKKAAIDPSAPARGEAGAPPTTTAATDK 1380
            PARPYKCTVCKESFTQKNILLVHYNSVSHLHKMKKAAIDPSAPARGEAGAPPTTTAATDK
Sbjct: 1405 PARPYKCTVCKESFTQKNILLVHYNSVSHLHKMKKAAIDPSAPARGEAGAPPTTTAATDK 1464

Query: 1381 PFKCTVCRVSYNQSSTLEIHMRSVLHQTRSRGTKTDSKIEGPERSQEEPKEGETEGEVGT 1440
            PFKCTVCRVSYNQSSTLEIHMRSVLHQTRSRGTKTDSKIEGPERSQEEPKEGETEGEVGT
Sbjct: 1465 PFKCTVCRVSYNQSSTLEIHMRSVLHQTRSRGTKTDSKIEGPERSQEEPKEGETEGEVGT 1524

Query: 1441 EKKGPDTSGFISGLPFLSPPPPPLDLHRFPAPLFTPPVLPPFPLVPESLLKLQQQQLLLP 1500
            EKKGPDTSGFISGLPFLSPPPPPLDLHRFPAPLFTPPVLPPFPLVPESLLKLQQQQLLLP
Sbjct: 1525 EKKGPDTSGFISGLPFLSPPPPPLDLHRFPAPLFTPPVLPPFPLVPESLLKLQQQQLLLP 1584

Query: 1501 FYLHDLKVGPKLTLAGPAPVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPSS 1560
            FYLHDLKVGPKLTLAGPAPVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPSS
Sbjct: 1585 FYLHDLKVGPKLTLAGPAPVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPSS 1644

Query: 1561 PPDPLPNEAARTAAKALLENFGFELVIQYNEGKQAVPPPPTPPPPEALGGGDKLACGACG 1620
            PPDPLPNEAARTAAKALLENFGFELVIQYNEGKQAVPPPPTPPPPEALGGGDKLACGACG
Sbjct: 1645 PPDPLPNEAARTAAKALLENFGFELVIQYNEGKQAVPPPPTPPPPEALGGGDKLACGACG 1704

Query: 1621 KLFSNMLILKTHEEHVHRRFLPFEALSRYAAQFRKSYDSLYPPLAEPPKPPDGSLDSPVP 1680
            KLFSNMLILKTHEEHVHRRFLPFEALSRYAAQFRKSYDSLYPPLAEPPKPPDGSLDSPVP
Sbjct: 1705 KLFSNMLILKTHEEHVHRRFLPFEALSRYAAQFRKSYDSLYPPLAEPPKPPDGSLDSPVP 1764

Query: 1681 HLGPPFLVPEPEAGGTRAPEERSRAGGHWPIEEEESSRGNLPPLVPAGRRFSRTKFTEFQ 1740
            HLGPPFLVPEPEAGGTRAPEERSRAGGHWPIEEEESSRGNLPPLVPAGRRFSRTKFTEFQ
Sbjct: 1765 HLGPPFLVPEPEAGGTRAPEERSRAGGHWPIEEEESSRGNLPPLVPAGRRFSRTKFTEFQ 1824

Query: 1741 TQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARKNACEGGSMPTGGGT 1800
            TQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARKNACEGGSMPTGGGT
Sbjct: 1825 TQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARKNACEGGSMPTGGGT 1884

Query: 1801 GGASGCRRCHATFSCVFELVRHLKKCYDDQTLEEEEEEAERGEEEEEVEEEEVEEEQGLE 1860
            GGASGCRRCHATFSCVFELVRHLKKCYDDQTLEEEEEEAERGEEEEEVEEEEVEEEQGLE
Sbjct: 1885 GGASGCRRCHATFSCVFELVRHLKKCYDDQTLEEEEEEAERGEEEEEVEEEEVEEEQGLE 1944

Query: 1861 PPAGPEGPLPEPPDGEELSQAEATKAGGKEPEEKATPSPSPAHTCDQCAISFSSQDLLTS 1920
            PPAGPEGPLPEPPDGEELSQAEATKAGGKEPEEKATPSPSPAHTCDQCAISFSSQDLLTS
Sbjct: 1945 PPAGPEGPLPEPPDGEELSQAEATKAGGKEPEEKATPSPSPAHTCDQCAISFSSQDLLTS 2004

Query: 1921 HRRLHFLPSLQPSAPPQLLDLPLLVFGERNPLVAATSPMPGPPLKRKHEDGSLSPTGSEA 1980
            HRRLHFLPSLQPSAPPQLLDLPLLVFGERNPLVAATSPMPGPPLKRKHEDGSLSPTGSEA
Sbjct: 2005 HRRLHFLPSLQPSAPPQLLDLPLLVFGERNPLVAATSPMPGPPLKRKHEDGSLSPTGSEA 2064

Query: 1981 GGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQ 2040
            GGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQ
Sbjct: 2065 GGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQ 2124

Query: 2041 NTRARERKGQFRSTPGGVPSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAF 2100
            NTRARERKGQFRSTPGGVPSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAF
Sbjct: 2125 NTRARERKGQFRSTPGGVPSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAF 2184

Query: 2101 PYPTATLASGPQPFLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESEACSLS 2160
            PYPTATLASGPQPFLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESEACSLS
Sbjct: 2185 PYPTATLASGPQPFLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESEACSLS 2244

Query: 2161 AGDLSDSSASSLAEPESPGAGGTSGGPGGGTGVPDGMGQRRYRTQMSSLQLKIMKACYEA 2220
            AGDLSDSSASSLAEPESPGAGGTSGGPGGGTGVPDGMGQRRYRTQMSSLQLKIMKACYEA
Sbjct: 2245 AGDLSDSSASSLAEPESPGAGGTSGGPGGGTGVPDGMGQRRYRTQMSSLQLKIMKACYEA 2304

Query: 2221 YRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAKLQGTAAGSTGGSSEGLLAAQRT 2280
            YRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAKLQGTAAGSTGGSSEGLLAAQRT
Sbjct: 2305 YRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAKLQGTAAGSTGGSSEGLLAAQRT 2364

Query: 2281 DCPYCDVKYDFYVSCRGHLFSRQHLAKLKEAVRAQLKSESKCYDLAPAPEAPPALKAPPA 2340
            DCPYCDVKYDFYVSCRGHLFSRQHLAKLKEAVRAQLKSESKCYDLAPAPEAPPALKAPPA
Sbjct: 2365 DCPYCDVKYDFYVSCRGHLFSRQHLAKLKEAVRAQLKSESKCYDLAPAPEAPPALKAPPA 2424

Query: 2341 TTPASMPLGAAPTLPRLAPVLLSGPALAQPPLGNLAPFNSGPAASSGLLGLATSVLPTTT 2400
            TTPASMPLGAAPTLPRLAPVLLSGPALAQPPLGNLAPFNSGPAASSGLLGLATSVLPTTT
Sbjct: 2425 TTPASMPLGAAPTLPRLAPVLLSGPALAQPPLGNLAPFNSGPAASSGLLGLATSVLPTTT 2484

Query: 2401 VVQTAGPGRPLPQRPMPDQTNTSTAGTTDPVPGPPTEPLGDKVSSERKPVAGPTSSSNDA 2460
            VVQTAGPGRPLPQRPMPDQTNTSTAGTTDPVPGPPTEPLGDKVSSERKPVAGPTSSSNDA
Sbjct: 2485 VVQTAGPGRPLPQRPMPDQTNTSTAGTTDPVPGPPTEPLGDKVSSERKPVAGPTSSSNDA 2544

Query: 2461 LKNLKALKTTVPALLGGQFLPFPLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNP 2520
            LKNLKALKTTVPALLGGQFLPFPLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNP
Sbjct: 2545 LKNLKALKTTVPALLGGQFLPFPLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNP 2604

Query: 2521 MIPQTLIGLLPNALLQPPPQPPEPTATAPPKPPELPAPGEGEAGEVDELLTGSTGISTVD 2580
            MIPQTLIGLLPNALLQPPPQPPEPTATAPPKPPELPAPGEGEAGEVDELLTGSTGISTVD
Sbjct: 2605 MIPQTLIGLLPNALLQPPPQPPEPTATAPPKPPELPAPGEGEAGEVDELLTGSTGISTVD 2664

Query: 2581 VTHRYLCRQCKMAFDGEAPATAHQRSFCFFGRGSGGSMPPPLRVPICTYHCLACEVLLSG 2640
            VTHRYLCRQCKMAFDGEAPATAHQRSFCFFGRGSGGSMPPPLRVPICTYHCLACEVLLSG
Sbjct: 2665 VTHRYLCRQCKMAFDGEAPATAHQRSFCFFGRGSGGSMPPPLRVPICTYHCLACEVLLSG 2724

Query: 2641 REALASHLRSSAHRRKAAPPQGGPPISITNAATAASAAVAFAKEEARLPHTDSNPKTTTT 2700
            REALASHLRSSAHRRKAAPPQGGPPISITNAATAASAAVAFAKEEARLPHTDSNPKTTTT
Sbjct: 2725 REALASHLRSSAHRRKAAPPQGGPPISITNAATAASAAVAFAKEEARLPHTDSNPKTTTT 2784

Query: 2701 STLLAL 2706
            STLLAL
Sbjct: 2785 STLLAL 2790


>gi|118498345 AT-binding transcription factor 1 [Homo sapiens]
          Length = 3703

 Score =  531 bits (1369), Expect = e-150
 Identities = 325/851 (38%), Positives = 455/851 (53%), Gaps = 103/851 (12%)

Query: 279  QEGDEGCKALI-SFLEPKLPARPSSD--IPLDNSSTVNMEANVAQTEDGPPEAEVQALIL 335
            +E DEGCK L  S L+ +L  RP  +      +SS  ++  +     + P         L
Sbjct: 485  EEEDEGCKGLFPSELDEELEDRPHEEPGAAAGSSSKKDLALSNQSISNSP---------L 535

Query: 336  LDEEVMALSPPSPPTATWDPSP----------------TQAKESPVAAGEAGPDWFPEGQ 379
            +   +  LS  +  T++   S                 ++   + VA G    D+  E  
Sbjct: 536  MPNVLQTLSRGTASTSSNSASSFVVFDGANRRNRLSFNSEGVRANVAEGGRRLDFADESA 595

Query: 380  EEDGGLCPPLNQSSPTSKEGGTLP--------APVGSPEDPSDPPQPYRLADDYTPAPAA 431
             +D    P  N+S+    +GG +P          +G  E PS         D    +   
Sbjct: 596  NKDNATAPEPNESTE-GDDGGFVPHHQHAGSLCELGVGECPSGSGVECPKCDTVLGSSR- 653

Query: 432  FQGLSLSSHMSLLHSRNSCKTLKCPKCNWHYKYQQTLDVHMREKHPESNSHCSYCSAGGA 491
                SL  HM+++HSRNSCKTLKCPKCNWHYKYQQTL+ HM+EKHPE    C YC +G  
Sbjct: 654  ----SLGGHMTMMHSRNSCKTLKCPKCNWHYKYQQTLEAHMKEKHPEPGGSCVYCKSGQP 709

Query: 492  HPRLARGESYNCGYKPYRCDVCNYSTTTKGNLSIHMQSDKHLANLQGFQAGPGGQ----- 546
            HPRLARGESY CGYKP+RC+VCNYSTTTKGNLSIHMQSDKHL N+Q  Q G G Q     
Sbjct: 710  HPRLARGESYTCGYKPFRCEVCNYSTTTKGNLSIHMQSDKHLNNMQNLQNGGGEQVFSHT 769

Query: 547  ---------GSPPEASLPPSAG---DKEPKTKSSWQCKVCSYETNISRNLRIHMTSEKHM 594
                      +   A++  S G     +PKTK +W+C+VC YETN++RNLRIHMTSEKHM
Sbjct: 770  AGAAAAAVAAAAAAANISSSCGAPSPTKPKTKPTWRCEVCDYETNVARNLRIHMTSEKHM 829

Query: 595  QNVLMLHQGLPLGLPPGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRP 654
             N+++L Q +        +G G  P P     +  EL+QY+  Q +  P   +       
Sbjct: 830  HNMMLLQQNMTQIQHNRHLGLGSLPSP-----AEAELYQYYLAQNMNLPNLKM------D 878

Query: 655  DKPLEAQLLLNGFH--HVGAPARKFPTSAPGSLSPDAHLPPSQLLGSSSDSLPTSPPPDD 712
                +AQ +++GF     G  A   P    G +  D  L   QL+     +L  S    +
Sbjct: 879  SAASDAQFMMSGFQLDPAGPMAAMTPALVGGEIPLDMRLGGGQLVSEELMNLGESFIQTN 938

Query: 713  SLSLKVFRCLVCQAFSTDSLELLLYHCSIGRSLPEAEWKEVAGDTHRCKLCCYGTQLKAN 772
              SLK+F+C VC  F+TD+L++L  H ++ RSL E EWK V GD+++CKLC Y TQLKAN
Sbjct: 939  DPSLKLFQCAVCNKFTTDNLDMLGLHMNVERSLSEDEWKAVMGDSYQCKLCRYNTQLKAN 998

Query: 773  FQLHLKTDKHAQKYQLAAHLREGGGA-MGTPSPASLGDGAPYGSVSPLHLRCNICDFESN 831
            FQLH KTDKH QKYQL AH++EGG A        ++G        +P+HL+CN CD+ +N
Sbjct: 999  FQLHCKTDKHVQKYQLVAHIKEGGKANEWRLKCVAIG--------NPVHLKCNACDYYTN 1050

Query: 832  SKEKMQLHARGAAHEENSQIYKVRLGAELGL------YHCLLCAWETPSRLAVLQHLRTP 885
            S EK++LH   + HE + ++YK     E G+      YHC+LC + T ++L ++QH+R+ 
Sbjct: 1051 SLEKLRLHTVNSRHEASLKLYKHLQQHESGVEGESCYYHCVLCNYSTKAKLNLIQHVRSM 1110

Query: 886  AHRDAQAQRRLQLLQNG-PTTEEGLAALQSILSFSHGQLRTPAEVVPAEAGNSQPGTIDP 944
             H+ +++ R+LQ LQ G P  +E L     I +        P E +    G S+    DP
Sbjct: 1111 KHQRSESLRKLQRLQKGLPEEDEDLG---QIFTIRRCPSTDPEEAIEDVEGPSETAA-DP 1166

Query: 945  EGTGEEPARGCQRLHLKKKKKKKKEWGRASAASKGLCDGGS--HPSLTLRPL---PICSL 999
            E   ++   G          + +KE   + A SK +   GS   P  + RP     I   
Sbjct: 1167 EELAKDQEGGA------SSSQAEKELTDSPATSKRISFPGSSESPLSSKRPKTAEEIKPE 1220

Query: 1000 QVYCCPYCSFLSPESSQVRAHTLSQHAVQPKYRCPLCQEQLVGRPALHFHLSHLHNVVPE 1059
            Q+Y CPYC + + + +++R H ++QH+VQP  RCPLCQ+ L  +  L  HL+HLH+V P+
Sbjct: 1221 QMYQCPYCKYSNADVNRLRVHAMTQHSVQPMLRCPLCQDMLNNKIHLQLHLTHLHSVAPD 1280

Query: 1060 CVEKLLLVVST 1070
            CVEKL++ V+T
Sbjct: 1281 CVEKLIMTVTT 1291



 Score =  256 bits (655), Expect = 2e-67
 Identities = 214/705 (30%), Positives = 297/705 (42%), Gaps = 192/705 (27%)

Query: 2162 GDLSDSSASSLAEPESPGAGGT-SGGPGGGTGVPDGMGQRRYRTQMSSLQLKIMKACYEA 2220
            G +  S  SSLA+P SP  G + S G  G +G  D  GQ+R+RTQM++LQLK++K+C+  
Sbjct: 2910 GTVDYSETSSLADPCSPSPGASGSAGKSGDSG--DRPGQKRFRTQMTNLQLKVLKSCFND 2967

Query: 2221 YRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAKLQGTAAGSTGGSSEGLLAAQRT 2280
            YRTPTM ECEVLG +IGLPKRV+QVWFQNARAKEKK+KL   +     G ++      +T
Sbjct: 2968 YRTPTMLECEVLGNDIGLPKRVVQVWFQNARAKEKKSKL---SMAKHFGINQTSYEGPKT 3024

Query: 2281 DCPYCDVKYDFYVSCRGHLFSRQHLAKLKEAVRAQLKSESKCYD------LAPAPEAPPA 2334
            +C  C +KY   +S R H+FS+QH++K+K+ + +QL  E + +D      L    E    
Sbjct: 3025 ECTLCGIKYSARLSVRDHIFSQQHISKVKDTIGSQLDKEKEYFDPATVRQLMAQQELDRI 3084

Query: 2335 LKAPPATTPASMPLG--------------AAPTLPRLAPVLLSGPALAQPPLGNLAPFNS 2380
             KA      A+   G              A P L  + PVLL  P L  P L    P N+
Sbjct: 3085 KKANEVLGLAAQQQGMFDNTPLQALNLPTAYPALQGIPPVLL--PGLNSPSLPGFTPSNT 3142

Query: 2381 G-PAASSGLLGLATSVLPTTTVVQTAGPGRPL-----------------PQRPMPDQTNT 2422
               +    L+GL ++ +P+  +  +  P +P                  PQ+P   Q   
Sbjct: 3143 ALTSPKPNLMGLPSTTVPSPGLPTSGLPNKPSSASLSSPTPAQATMAMGPQQPPQQQQQQ 3202

Query: 2423 STAGTTDPVPGPPTEPL-----------------GDKVSSERK-------PVAGPTSSSN 2458
                   P P P  +P                   +KV  + K       P+  P     
Sbjct: 3203 QQPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKVKEKEKAHKGKGEPLPVPKKEKG 3262

Query: 2459 DA-----------------------LKNLKALKTTVP-ALLGGQFLPFPLPPAGGTAPPA 2494
            +A                       L+ L+A  T+ P ALL  QFLP+ +P       P 
Sbjct: 3263 EAPTATAATISAPLPTMEYAVDPAQLQALQAALTSDPTALLTSQFLPYFVPGFSPYYAPQ 3322

Query: 2495 VFGPQLQGAYFQQLYGMKKGLFPMNPMIPQTLIGLLPNALLQ------------------ 2536
            + G  LQ  Y Q +YGM +GLFP +P + Q L+GL P +LLQ                  
Sbjct: 3323 IPG-ALQSGYLQPMYGM-EGLFPYSPALSQALMGLSPGSLLQQYQQYQQSLQEAIQQQQQ 3380

Query: 2537 -----------------------PP--PQPPEPTATAPPKP--------------PELPA 2557
                                   PP  P P +  A   PKP              P+LP 
Sbjct: 3381 RQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDPAKESPKPEEQKNTPREVSPLLPKLPE 3440

Query: 2558 PGEGEAGEVDELLTGSTGISTVDVTHRYLCRQCKMAFDGEAPATAHQRSFCFFGRGSGGS 2617
              E E+   D L           V ++ +CR+C+  F  E  A +H +S CFFG+     
Sbjct: 3441 EPEAESKSADSLY---DPFIVPKVQYKLVCRKCQAGFSDEEAARSHLKSLCFFGQSVVNL 3497

Query: 2618 MPPPLRVPI--------------------CTYHCLACEVLLSGREALASHLRSSAHRRKA 2657
                L VP                      +YHCLACE  L G EAL+ HL S+ H+ + 
Sbjct: 3498 QEMVLHVPTGGGGGGSGGGGGGGGGGGGGGSYHCLACESALCGEEALSQHLESALHKHR- 3556

Query: 2658 APPQGGPPISITNAATAASAAVAFAKEEARLPHTDSNPKTTTTST 2702
                     +IT AA  A       +  + LPH+   P  +T ST
Sbjct: 3557 ---------TITRAARNAK------EHPSLLPHSACFPDPSTAST 3586



 Score =  169 bits (427), Expect = 4e-41
 Identities = 179/722 (24%), Positives = 275/722 (38%), Gaps = 207/722 (28%)

Query: 1264 VPEPDAQAEDVAPPPTMAEEEEGTTGELRSAEPAPADSRHPLTYRKTTNFALDKFLDPAR 1323
            V E   +  D+    +    + G+  E   +EP  A     L +RK  NF ++KFLDP+R
Sbjct: 1489 VEEDKEEESDLEDKQSPTGSDSGSVQEDSGSEPKRA-----LPFRKGPNFTMEKFLDPSR 1543

Query: 1324 PYKCTV---------------------------------------------------CKE 1332
            PYKCTV                                                   C  
Sbjct: 1544 PYKCTVCKESFTQKNILLVHYNSVSHLHKLKRALQESATGQPEPTSSPDNKPFKCNTCNV 1603

Query: 1333 SFTQKNILLVHYNSVSHLHKMKKAAIDPSAPARGEAGAPPTTTAATDKPFKCTVCR---- 1388
            +++Q + L +H  SV H  K + A ++ ++ +    G   + + ++  P   +       
Sbjct: 1604 AYSQSSTLEIHMRSVLHQTKARAAKLEAASGSSNGTGNSSSISLSSSTPSPVSTSGSNTF 1663

Query: 1389 VSYNQSSTLEIHMRSVLHQTRSR-------GTKTDSKIEGPE----------------RS 1425
             + N SS       ++L Q  +        G    + I  P                 R 
Sbjct: 1664 TTSNPSSAGIAPSSNLLSQVPTESVGMPPLGNPIGANIASPSEPKEANRKKLADMIASRQ 1723

Query: 1426 QEEPKEGETEGEVGTEKKGPDTSGFISGLPFLSPPPPPLDLHRFPAPLFTPPVLPPFPLV 1485
            Q++ ++ + + +   +++    +   + +                + LF P +LP FP+ 
Sbjct: 1724 QQQQQQQQQQQQQQQQQQAQTLAQAQAQVQAHLQQELQQQAALIQSQLFNPTLLPHFPMT 1783

Query: 1486 PESLLKLQQQQ-LLLPFYLH--DLKVGPK---------LTLAGPAPVL--SLPAATPPPP 1531
             E+LL+LQQQQ LL PFY+   + ++ P+         LTL G  P L   L A    P 
Sbjct: 1784 TETLLQLQQQQHLLFPFYIPSAEFQLNPEVSLPVTSGALTLTGTGPGLLEDLKAQVQVPQ 1843

Query: 1532 -------PQPPKAELA--------------------------EREWERPPMAKEGNEAG- 1557
                   PQ  + +L+                          E+E +R   + EG E   
Sbjct: 1844 QSHQQILPQQQQNQLSIAQSHSALLQPSQHPEKKNKLVIKEKEKESQRERDSAEGGEGNT 1903

Query: 1558 -------------------------PSSPPDPLPNEAARTAAKALLENFGFELVIQYNEG 1592
                                     PS  P  + ++A   A KALLENFGFELVIQYNE 
Sbjct: 1904 GPKETLPDALKAKEKKELAPGGGSEPSMLPPRIASDARGNATKALLENFGFELVIQYNEN 1963

Query: 1593 KQAVPPPPTPPPP-EALGGGDKLACGACGKLFSNMLILKTHEEHVHRRFLPFEALSRYAA 1651
            KQ V          E L   +KL C +CGKLFSN+LILK+H+EHVH+ + PF+ L R+A 
Sbjct: 1964 KQKVQKKNGKTDQGENL---EKLECDSCGKLFSNILILKSHQEHVHQNYFPFKQLERFAK 2020

Query: 1652 QFRKSYDSLY---PPLAEPPKPPDGSLDSPVPHLGP-PFLVP------EPEAGGTRAPEE 1701
            Q+R  YD LY   P   EPP PP      P+P   P P   P       P    T AP +
Sbjct: 2021 QYRDHYDKLYPLRPQTPEPPPPPPPPPPPPLPAAPPQPASTPAIPASAPPITSPTIAPAQ 2080

Query: 1702 RSRAGGHWPIEEE--------------ESSRGNLPP-----------------------L 1724
             S       +  E              ++    LPP                       L
Sbjct: 2081 PSVPLTQLSMPMELPIFSPLMMQTMPLQTLPAQLPPQLGPVEPLPADLAQLYQHQLNPTL 2140

Query: 1725 VPAGRRFSRTKFTEFQTQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKA 1784
            +    +  RT+ T+ Q + L+ +F+ +  P + +++ +A   GL  +V+  WF+N   K 
Sbjct: 2141 LQQQNKRPRTRITDDQLRVLRQYFDINNSPSEEQIKEMADKSGLPQKVIKHWFRNTLFKE 2200

Query: 1785 RK 1786
            R+
Sbjct: 2201 RQ 2202



 Score =  169 bits (427), Expect = 4e-41
 Identities = 111/264 (42%), Positives = 150/264 (56%), Gaps = 40/264 (15%)

Query: 1829 DQTLEEEEEEAERGEEEEEVEEEEVEEEQGL----------EPPAG---PEGPLPEP-PD 1874
            +QT E++ +     +++E+ E++    +Q L          +PP     P+ PLP+  P 
Sbjct: 2441 NQTQEKQGQPKPELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPPPQAPPPQCPLPQSSPS 2500

Query: 1875 GEELSQAEATKAGGKEPEEKATPSPSPA-HTCDQCAISFSSQDLLTSHRRLHFLPSLQPS 1933
              +LS           P++ A   P    + CDQC ++F S +    H++LHFL +    
Sbjct: 2501 PSQLSHLPLKPLHTSTPQQLANLPPQLIPYQCDQCKLAFPSFEHWQEHQQLHFLSAQNQF 2560

Query: 1934 APPQLLD----LPLLVFGERNPLVAA-------------TSPMPGPP------LKRKHED 1970
              PQ LD    +P ++F   NPL+A+             ++  P  P      LKRK E+
Sbjct: 2561 IHPQFLDRSLDMPFMLFDPSNPLLASQLLSGAIPQIPASSATSPSTPTSTMNTLKRKLEE 2620

Query: 1971 -GSLSPTGSEAGGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVG 2029
              S SP  +++G GGE EP RDKRLRTTI PEQLEILY+ Y+ DSNPTRKMLD I+ EVG
Sbjct: 2621 KASASPGENDSGTGGE-EPQRDKRLRTTITPEQLEILYQKYLLDSNPTRKMLDHIAHEVG 2679

Query: 2030 LKKRVVQVWFQNTRARERKGQFRS 2053
            LKKRVVQVWFQNTRARERKGQFR+
Sbjct: 2680 LKKRVVQVWFQNTRARERKGQFRA 2703



 Score =  114 bits (284), Expect = 2e-24
 Identities = 129/504 (25%), Positives = 189/504 (37%), Gaps = 100/504 (19%)

Query: 1528 PPPPPQPPKAELAEREWERPPMAKEGNEAGPSSPPDPLPNEAARTAAKALLE-NFGFELV 1586
            PPPPP PP    A      PP          S+PP   P  A    +  L + +   EL 
Sbjct: 2042 PPPPPPPPPLPAA------PPQPASTPAIPASAPPITSPTIAPAQPSVPLTQLSMPMELP 2095

Query: 1587 IQYNEGKQAVPPPPTPPP-PEALGGGDKLACGACGKLFSNML---ILKTHEEHVHRRFLP 1642
            I      Q +P    P   P  LG  + L      +L+ + L   +L+   +    R   
Sbjct: 2096 IFSPLMMQTMPLQTLPAQLPPQLGPVEPLPADLA-QLYQHQLNPTLLQQQNKRPRTRITD 2154

Query: 1643 --FEALSRYAAQFRKSYDSLYPPLAEPPKPPDGSL----------------DSPVPHLGP 1684
                 L +Y        +     +A+    P   +                DSP     P
Sbjct: 2155 DQLRVLRQYFDINNSPSEEQIKEMADKSGLPQKVIKHWFRNTLFKERQRNKDSPYNFSNP 2214

Query: 1685 PFLVPEPEAGGTRAPEERSRAGGHWPIEEEESSRGNLPPLVPAGRRFSRTKFTEFQTQAL 1744
            P    E     +R P        +W                   +R SRT+FT++Q + L
Sbjct: 2215 PITSLEELKIDSRPPSPEPPKQEYW-----------------GSKRSSRTRFTDYQLRVL 2257

Query: 1745 QSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARKNACEGGSMPTGGGTGGAS 1804
            Q FF+ +AYPKD E E+L++LL L +RV+VVWFQNARQKARKN    G    G      +
Sbjct: 2258 QDFFDANAYPKDDEFEQLSNLLNLPTRVIVVWFQNARQKARKNYENQGEGKDGERRELTN 2317

Query: 1805 G-----------CRRCHATFSCVFELVRHLKK-CYDDQTLEEEEEEAERGEEEEEVEEEE 1852
                        C++C   F  +F+L++H KK CY D    E+EE  +  + E+ ++  E
Sbjct: 2318 DRYIRTSNLNYQCKKCSLVFQRIFDLIKHQKKLCYKD----EDEEGQDDSQNEDSMDAME 2373

Query: 1853 VEEEQGLE-----PPAGPEGPLPE------------PPDGEELSQAEA-TKAGGKEPEEK 1894
            +            P      P P               + EEL+   + T+AG ++P+  
Sbjct: 2374 ILTPTSSSCSTPMPSQAYSAPAPSANNTASSAFLQLTAEAEELATFNSKTEAGDEKPKLA 2433

Query: 1895 ATPSPSPAHTCDQCA--------------ISFSSQDLLTSHRRLHFLPSLQPSAPPQLLD 1940
              PS  P  T ++                 + + Q  L     L  LP   P APP    
Sbjct: 2434 EAPSAQPNQTQEKQGQPKPELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPPPQAPPPQCP 2493

Query: 1941 LPLLVFGERNPLVAATSPMPGPPL 1964
            LP     + +P  +  S +P  PL
Sbjct: 2494 LP-----QSSPSPSQLSHLPLKPL 2512



 Score = 76.6 bits (187), Expect = 3e-13
 Identities = 138/601 (22%), Positives = 205/601 (34%), Gaps = 139/601 (23%)

Query: 1520 VLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPSSPPDPLPNEAARTAAKALLE 1579
            ++SLP+  P PPPQ P           PP       +   S    LP +   T+    L 
Sbjct: 2474 LVSLPSL-PQPPPQAP-----------PPQCPLPQSSPSPSQLSHLPLKPLHTSTPQQLA 2521

Query: 1580 NFGFELVIQYNEGKQAVPPPPTPPPPEALGGGDKLACGACGKLFSNMLILKTHEE----H 1635
            N               +PP   P             C  C   F +    + H++     
Sbjct: 2522 N---------------LPPQLIP-----------YQCDQCKLAFPSFEHWQEHQQLHFLS 2555

Query: 1636 VHRRFLPFEALSRYAAQFRKSYDSLYPPLAEP------PKPPDGSLDSP-VPHLGPPFLV 1688
               +F+  + L R        +D   P LA        P+ P  S  SP  P      L 
Sbjct: 2556 AQNQFIHPQFLDRSLDMPFMLFDPSNPLLASQLLSGAIPQIPASSATSPSTPTSTMNTLK 2615

Query: 1689 PEPEAGGTRAPEER-SRAGGHWPIEEEESSRGNLPPLVPAGRRFSRTKFTEFQTQALQSF 1747
             + E   + +P E  S  GG  P  ++                  RT  T  Q + L   
Sbjct: 2616 RKLEEKASASPGENDSGTGGEEPQRDKRL----------------RTTITPEQLEILYQK 2659

Query: 1748 FETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARKNACEGGSMPTGGGTGGASGCR 1807
            +   + P    ++ +A  +GL  RVV VWFQN R + RK     G     G       C 
Sbjct: 2660 YLLDSNPTRKMLDHIAHEVGLKKRVVQVWFQNTRARERK-----GQFRAVGPAQAHRRCP 2714

Query: 1808 RCHATFSCVFELVRHLKKCYDDQTLEEEEEEAERGEEEEEVEEEEVEEEQGLE------- 1860
             C A F     L  H++             EA+R      +    ++ + GL+       
Sbjct: 2715 FCRALFKAKTALEAHIR--------SRHWHEAKRAGYNLTLSAMLLDCDGGLQMKGDIFD 2766

Query: 1861 -------PPAGPEG---PLPEPPDGEELS-----QAEATKAGGKEPEEKATPSPSPAH-- 1903
                   PP+  +G   PL       ELS        + K  G E  E  +PS S  +  
Sbjct: 2767 GTSFSHLPPSSSDGQGVPLSPVSKTMELSPRTLLSPSSIKVEGIEDFE--SPSMSSVNLN 2824

Query: 1904 ------TCDQC-AISFSSQDLLT-------SHRRLHFLPSLQPSAPPQ--LLDLPLLVFG 1947
                    D C +++ +  D  T       +          + S+ P   L    ++   
Sbjct: 2825 FDQTKLDNDDCSSVNTAITDTTTGDEGNADNDSATGIATETKSSSAPNEGLTKAAMMAMS 2884

Query: 1948 ERNPLVAATSPMPGPPLKRKHEDG----------------SLSP--TGSEAGGGGEGEPP 1989
            E    +++    P P    K  D                 S SP  +GS    G  G+ P
Sbjct: 2885 EYEDRLSSGLVSPAPSFYSKEYDNEGTVDYSETSSLADPCSPSPGASGSAGKSGDSGDRP 2944

Query: 1990 RDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQNTRARERKG 2049
              KR RT +   QL++L   +     PT    + +  ++GL KRVVQVWFQN RA+E+K 
Sbjct: 2945 GQKRFRTQMTNLQLKVLKSCFNDYRTPTMLECEVLGNDIGLPKRVVQVWFQNARAKEKKS 3004

Query: 2050 Q 2050
            +
Sbjct: 3005 K 3005



 Score = 71.2 bits (173), Expect = 1e-11
 Identities = 46/159 (28%), Positives = 72/159 (45%), Gaps = 12/159 (7%)

Query: 2150 ASPESEACSLSAGDLSDSSASSLAEPESPGAGGTSGGPGGGTGVPDGMGQRRYRTQMSSL 2209
            A P+  A S ++     S+ ++L       A  + G    GTG  +    +R RT ++  
Sbjct: 2592 AIPQIPASSATSPSTPTSTMNTLKRKLEEKASASPGENDSGTGGEEPQRDKRLRTTITPE 2651

Query: 2210 QLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAKLQGTAAGSTGG 2269
            QL+I+   Y     PT +  + +  E+GL KRV+QVWFQN RA+E+K + +         
Sbjct: 2652 QLEILYQKYLLDSNPTRKMLDHIAHEVGLKKRVVQVWFQNTRARERKGQFRAVGP----- 2706

Query: 2270 SSEGLLAAQRTDCPYCDVKYDFYVSCRGHLFSRQ-HLAK 2307
                  A     CP+C   +    +   H+ SR  H AK
Sbjct: 2707 ------AQAHRRCPFCRALFKAKTALEAHIRSRHWHEAK 2739



 Score = 58.2 bits (139), Expect = 1e-07
 Identities = 104/406 (25%), Positives = 147/406 (36%), Gaps = 55/406 (13%)

Query: 2199 QRRYRTQMSSLQLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAK 2258
            +R  RT+ +  QL++++  ++A   P   E E L   + LP RVI VWFQNAR K +K  
Sbjct: 2242 KRSSRTRFTDYQLRVLQDFFDANAYPKDDEFEQLSNLLNLPTRVIVVWFQNARQKARK-N 2300

Query: 2259 LQGTAAGSTGGSSEGLLAAQR--------TDCPYCDVKYDFYVSCRGHLFSRQHLAKLKE 2310
             +    G  G   E  L   R          C  C + +        H   ++ L    E
Sbjct: 2301 YENQGEGKDGERRE--LTNDRYIRTSNLNYQCKKCSLVFQRIFDLIKH---QKKLCYKDE 2355

Query: 2311 AVRAQLKSESKCYDLAPAPE----APPALKAPPATTPASMPLGAAPTLPRLAPVLLSGPA 2366
                Q  S+++  D   A E       +   P  +   S P  +A      A + L+  A
Sbjct: 2356 DEEGQDDSQNE--DSMDAMEILTPTSSSCSTPMPSQAYSAPAPSANNTASSAFLQLTAEA 2413

Query: 2367 LAQPPLGNLAPFNSGPAA--SSGLLGLATSVLPTTTVVQTAGPGRPLPQRPMPDQ-TNTS 2423
                    LA FNS   A      L  A S  P  T  +   P   L Q+  P+Q TNT 
Sbjct: 2414 ------EELATFNSKTEAGDEKPKLAEAPSAQPNQTQEKQGQPKPELQQQEQPEQKTNTP 2467

Query: 2424 TAGTTDPV--PGPPTEPLGDKVSSERKPVAGPTSSSNDALKNLKALKTTVP---ALLGGQ 2478
                   V  P  P  P          P + P+ S    L  LK L T+ P   A L  Q
Sbjct: 2468 QQKLPQLVSLPSLPQPPPQAPPPQCPLPQSSPSPSQLSHLP-LKPLHTSTPQQLANLPPQ 2526

Query: 2479 FLPFPLPPAGGTAPPAVFGPQLQGAYF-------------QQLYGMKKGLF-PMNPMI-P 2523
             +P+         P      + Q  +F              +   M   LF P NP++  
Sbjct: 2527 LIPYQCDQCKLAFPSFEHWQEHQQLHFLSAQNQFIHPQFLDRSLDMPFMLFDPSNPLLAS 2586

Query: 2524 QTLIGLLPNALLQPPPQPPEPTATAPPKPPEL-----PAPGEGEAG 2564
            Q L G +P         P  PT+T      +L      +PGE ++G
Sbjct: 2587 QLLSGAIPQIPASSATSPSTPTSTMNTLKRKLEEKASASPGENDSG 2632



 Score = 53.5 bits (127), Expect = 3e-06
 Identities = 52/210 (24%), Positives = 97/210 (46%), Gaps = 35/210 (16%)

Query: 1862 PAGPEGPLPEPPDGEELSQAEATKAGGKEPEEKATPSPSPAHTCDQCAISFSSQDLLTSH 1921
            P  PE P P PP                 P   A P P PA T    AI  S+  + +  
Sbjct: 2034 PQTPEPPPPPPPP--------------PPPPLPAAP-PQPASTP---AIPASAPPITSPT 2075

Query: 1922 RRLHFLPSLQPSAPPQLLDLP--LLVFGERNPLVAATSPMPGPPLKRKHEDGSLSPTGSE 1979
                 +   QPS P   L +P  L +F   +PL+  T P+   P +   + G + P  ++
Sbjct: 2076 -----IAPAQPSVPLTQLSMPMELPIF---SPLMMQTMPLQTLPAQLPPQLGPVEPLPAD 2127

Query: 1980 AGGGGEGE------PPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKR 2033
                 + +        ++KR RT I  +QL +L +++  +++P+ + +  ++++ GL ++
Sbjct: 2128 LAQLYQHQLNPTLLQQQNKRPRTRITDDQLRVLRQYFDINNSPSEEQIKEMADKSGLPQK 2187

Query: 2034 VVQVWFQNTRARERKGQFRSTPGGVPSPAV 2063
            V++ WF+NT  +ER+ + + +P    +P +
Sbjct: 2188 VIKHWFRNTLFKERQ-RNKDSPYNFSNPPI 2216



 Score = 50.4 bits (119), Expect = 2e-05
 Identities = 40/171 (23%), Positives = 72/171 (42%), Gaps = 30/171 (17%)

Query: 2111 PQPFLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESEACSLSAGDLSDSSAS 2170
            P+P  PP      P P PPLP  PP P S    P   P  +  + A +  +  L+  S  
Sbjct: 2037 PEPPPPP-----PPPPPPPLPAAPPQPASTPAIPASAPPITSPTIAPAQPSVPLTQLSMP 2091

Query: 2171 SLAEPESPGAGGTSGGPGGGTGVPDGMG-------------------------QRRYRTQ 2205
                  SP    T         +P  +G                          +R RT+
Sbjct: 2092 MELPIFSPLMMQTMPLQTLPAQLPPQLGPVEPLPADLAQLYQHQLNPTLLQQQNKRPRTR 2151

Query: 2206 MSSLQLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKK 2256
            ++  QL++++  ++   +P+ ++ + + ++ GLP++VI+ WF+N   KE++
Sbjct: 2152 ITDDQLRVLRQYFDINNSPSEEQIKEMADKSGLPQKVIKHWFRNTLFKERQ 2202



 Score = 49.3 bits (116), Expect = 5e-05
 Identities = 31/105 (29%), Positives = 41/105 (39%), Gaps = 21/105 (20%)

Query: 1323 RPYKCTVCKESFTQKNILLVHYNSVSHLHKMKK---------------------AAIDPS 1361
            +P++C VC  S T K  L +H  S  HL+ M+                      AA   +
Sbjct: 724  KPFRCEVCNYSTTTKGNLSIHMQSDKHLNNMQNLQNGGGEQVFSHTAGAAAAAVAAAAAA 783

Query: 1362 APARGEAGAPPTTTAATDKPFKCTVCRVSYNQSSTLEIHMRSVLH 1406
            A      GAP  T   T   ++C VC    N +  L IHM S  H
Sbjct: 784  ANISSSCGAPSPTKPKTKPTWRCEVCDYETNVARNLRIHMTSEKH 828



 Score = 47.0 bits (110), Expect = 3e-04
 Identities = 32/89 (35%), Positives = 42/89 (47%), Gaps = 12/89 (13%)

Query: 506  KPYRCDVCNYSTTTKGNLSIHMQSDKHLANL-QGFQAGPGGQGSPPEASLPPSAGDKEPK 564
            +PY+C VC  S T K  L +H  S  HL  L +  Q    GQ   PE   P S+ D +P 
Sbjct: 1543 RPYKCTVCKESFTQKNILLVHYNSVSHLHKLKRALQESATGQ---PE---PTSSPDNKP- 1595

Query: 565  TKSSWQCKVCSYETNISRNLRIHMTSEKH 593
                ++C  C+   + S  L IHM S  H
Sbjct: 1596 ----FKCNTCNVAYSQSSTLEIHMRSVLH 1620



 Score = 45.1 bits (105), Expect = 0.001
 Identities = 72/308 (23%), Positives = 113/308 (36%), Gaps = 60/308 (19%)

Query: 23  LPSDTFSSSTPSDPVTKDPPAASSTSENMRSSEPGGQLLESGCGLVPPKEIGEPQEGPDC 82
           L   T S+  PS+P +K+    +  S +  S +     +E  C    P         P  
Sbjct: 61  LAESTASAGPPSEPASKEV-TCNECSASFASLQT---YMEHHCPSARPP--------PPL 108

Query: 83  GHFPPNDPGVEKDKEQEEEEEGLPPMDLSNHLFFTAGGEAYLVAKLSL---------PGG 133
                +D G E D+E + E       +L+  + +   G AY+V  LS           G 
Sbjct: 109 REESASDTGEEGDEESDVE-------NLAGEIVYQPDGSAYIVESLSQLTQGGGACGSGS 161

Query: 134 SELLLPKGF----PWGEAGIKEEPSLPFLAYPPPSHLTALHIQHGFD-----PIQGFSSS 184
               LP  F    P G  G + +PS     YP    +   HI   F      P Q F ++
Sbjct: 162 GSGPLPSLFLNSLP-GAGGKQGDPSCAAPVYP--QIINTFHIASSFGKWFEGPDQAFPNT 218

Query: 185 DQILSHDTSAPSPAACEERHGAFWSYQLAPNPPGDPKDGPMGNSGGNHVAV--------- 235
             +        S    + RH +   Y    N  G  K   +     N+V +         
Sbjct: 219 SALAGLSPVLHSFRVFDVRHKSNKDYL---NSDGSAKSSCVSKDVPNNVDLSKFDGFVLY 275

Query: 236 -----FWLCLLCRLGFSKPQAFMDH-TQSHGVKLTPAQYQGLSGS--PAVLQEGDEGCKA 287
                  +C LC+L F   ++F+ H    H + L+  + + LS     A++Q   +  + 
Sbjct: 276 GKRKPILMCFLCKLSFGYVRSFVTHAVHDHRMTLSEDERKILSNKNISAIIQGIGKDKEP 335

Query: 288 LISFLEPK 295
           L+SFLEPK
Sbjct: 336 LVSFLEPK 343



 Score = 45.1 bits (105), Expect = 0.001
 Identities = 81/389 (20%), Positives = 127/389 (32%), Gaps = 104/389 (26%)

Query: 1845 EEEVEEEEVEEEQGLEPPAGPEGPLPEPP----------DGEELSQAEATKAGGKE--PE 1892
            +++ ++++ + +Q   PPA    P P+ P          D E++ + E    G  E  P 
Sbjct: 3197 QQQQQQQQPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKVKEKEKAHKGKGEPLPV 3256

Query: 1893 EKATPSPSPAHTCDQCAISFSSQDLLTSHRRLHFLPSLQPSAPPQLLDLPLLVFGERNPL 1952
             K     +P  T    +    + +      +L  L +   S P  LL    L +      
Sbjct: 3257 PKKEKGEAPTATAATISAPLPTMEYAVDPAQLQALQAALTSDPTALLTSQFLPY-----F 3311

Query: 1953 VAATSPMPGPPLKRKHEDGSLSPTGSEAGGGGEGEPPRDKRLRTTIL---PEQLEILYRW 2009
            V   SP   P +    + G L P       G EG  P    L   ++   P  L   Y+ 
Sbjct: 3312 VPGFSPYYAPQIPGALQSGYLQPM-----YGMEGLFPYSPALSQALMGLSPGSLLQQYQQ 3366

Query: 2010 YMQDSNPTRKMLDCISEEVGLKKRVVQVWFQNTRARERKGQFRSTPGGVPSPAVKPPATA 2069
            Y Q       + + I ++   ++++ Q   Q  + ++ K      P G PSP        
Sbjct: 3367 YQQ------SLQEAIQQQ--QQRQLQQQQQQKVQQQQPKASQTPVPPGAPSP-------- 3410

Query: 2070 TPASLPKFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQPFLPPGKEATTPTP-EP 2128
                           D    +E+PK                      P ++  TP    P
Sbjct: 3411 ---------------DKDPAKESPK----------------------PEEQKNTPREVSP 3433

Query: 2129 PLPLLPPPPPSEEEG------PEEPPKASPESEACSLSAGDLSDSSASS----------- 2171
             LP LP  P +E +       P   PK   +       AG   + +A S           
Sbjct: 3434 LLPKLPEEPEAESKSADSLYDPFIVPKVQYKLVCRKCQAGFSDEEAARSHLKSLCFFGQS 3493

Query: 2172 --------LAEPESPGAGGTSGGPGGGTG 2192
                    L  P   G GG+ GG GGG G
Sbjct: 3494 VVNLQEMVLHVPTGGGGGGSGGGGGGGGG 3522



 Score = 40.4 bits (93), Expect = 0.024
 Identities = 25/62 (40%), Positives = 33/62 (53%), Gaps = 4/62 (6%)

Query: 1797 GGGTGGASGCRRCHATFSCVFELVRHLKKCYDDQTLEEEEEEAERGEEEEEVEEEEVEEE 1856
            G  +G A G ++      C  E V       +++  EEEEEE    EEEEE EEEE EE+
Sbjct: 433  GKDSGAAEGEKQEVGDGDCFSEKVEPA----EEEAEEEEEEEEAEEEEEEEEEEEEEEED 488

Query: 1857 QG 1858
            +G
Sbjct: 489  EG 490



 Score = 40.4 bits (93), Expect = 0.024
 Identities = 34/115 (29%), Positives = 42/115 (36%), Gaps = 26/115 (22%)

Query: 602  QGLPLGLPPGLMGPGPP--PPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLR----PD 655
            QG+P  L PGL  P  P   P     TSP        P  +G P T +  PGL     P+
Sbjct: 3119 QGIPPVLLPGLNSPSLPGFTPSNTALTSPK-------PNLMGLPSTTVPSPGLPTSGLPN 3171

Query: 656  KPLEAQLLLNGFHHVGAPARKFPTSAPGSLSPDAHLPPSQLLGSSSDSLPTSPPP 710
            KP  A L               PT A  +++     PP Q        +   PPP
Sbjct: 3172 KPSSASL-------------SSPTPAQATMAMGPQQPPQQQQQQQQPQVQQPPPP 3213



 Score = 40.0 bits (92), Expect = 0.031
 Identities = 25/53 (47%), Positives = 31/53 (58%), Gaps = 3/53 (5%)

Query: 1826 CYDDQTLEEEEEEAERGEEEEEVEEEE--VEEEQGLEPPAGPEGPLPEPPDGE 1876
            C+ ++ +E  EEEAE  EEEEE EEEE   EEE+  E   G +G  P   D E
Sbjct: 451  CFSEK-VEPAEEEAEEEEEEEEAEEEEEEEEEEEEEEEDEGCKGLFPSELDEE 502



 Score = 38.5 bits (88), Expect = 0.091
 Identities = 37/167 (22%), Positives = 56/167 (33%), Gaps = 14/167 (8%)

Query: 1253 PGQPPSPAPSPVPEPDAQAEDVAPPPTMAEEEEGTTGELRSAEPAPADSRHPLTYRKTTN 1312
            P    +P P   P PD      +P P   EE++ T  E+    P   +   P    K+ +
Sbjct: 3396 PKASQTPVPPGAPSPDKDPAKESPKP---EEQKNTPREVSPLLPKLPEE--PEAESKSAD 3450

Query: 1313 FALDKFLDPARPYK--CTVCKESFTQKNILLVHYNS-------VSHLHKMKKAAIDPSAP 1363
               D F+ P   YK  C  C+  F+ +     H  S       V +L +M          
Sbjct: 3451 SLYDPFIVPKVQYKLVCRKCQAGFSDEEAARSHLKSLCFFGQSVVNLQEMVLHVPTGGGG 3510

Query: 1364 ARGEAGAPPTTTAATDKPFKCTVCRVSYNQSSTLEIHMRSVLHQTRS 1410
                 G            + C  C  +      L  H+ S LH+ R+
Sbjct: 3511 GGSGGGGGGGGGGGGGGSYHCLACESALCGEEALSQHLESALHKHRT 3557



 Score = 37.4 bits (85), Expect = 0.20
 Identities = 23/97 (23%), Positives = 41/97 (42%), Gaps = 12/97 (12%)

Query: 758  HRCKLCCYGTQLKANFQLHLKTDKHAQKYQLAAHLREGGGAMGTPSPASLGDGAPYGSVS 817
            ++C +C      K    +H  +  H  K + A  L+E   A G P P S  D  P+    
Sbjct: 1545 YKCTVCKESFTQKNILLVHYNSVSHLHKLKRA--LQES--ATGQPEPTSSPDNKPF---- 1596

Query: 818  PLHLRCNICDFESNSKEKMQLHARGAAHEENSQIYKV 854
                +CN C+   +    +++H R   H+  ++  K+
Sbjct: 1597 ----KCNTCNVAYSQSSTLEIHMRSVLHQTKARAAKL 1629



 Score = 37.0 bits (84), Expect = 0.26
 Identities = 21/68 (30%), Positives = 33/68 (48%), Gaps = 6/68 (8%)

Query: 1987 EPPRD------KRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQ 2040
            EPP+       +  RT     QL +L  ++  ++ P     + +S  + L  RV+ VWFQ
Sbjct: 2232 EPPKQEYWGSKRSSRTRFTDYQLRVLQDFFDANAYPKDDEFEQLSNLLNLPTRVIVVWFQ 2291

Query: 2041 NTRARERK 2048
            N R + RK
Sbjct: 2292 NARQKARK 2299



 Score = 35.0 bits (79), Expect = 1.0
 Identities = 123/613 (20%), Positives = 197/613 (32%), Gaps = 136/613 (22%)

Query: 1877 ELSQAEATKAGGKEPEEKATPSPSPAHTCDQCAISFSSQDLLTSHRR--LHFLP------ 1928
            +L +A    A G +PE  ++P   P   C+ C +++S    L  H R  LH         
Sbjct: 1572 KLKRALQESATG-QPEPTSSPDNKP-FKCNTCNVAYSQSSTLEIHMRSVLHQTKARAAKL 1629

Query: 1929 ----------------SLQPSAPPQLLDLPLLVFGERNPLVAATSPMPGPPLKRKHEDGS 1972
                            SL  S P  +       F   NP  A  +P      +   E   
Sbjct: 1630 EAASGSSNGTGNSSSISLSSSTPSPVSTSGSNTFTTSNPSSAGIAPSSNLLSQVPTESVG 1689

Query: 1973 LSPTGSEAGGG----GEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEV 2028
            + P G+  G       E +    K+L   I   Q +   +   Q     ++    +++  
Sbjct: 1690 MPPLGNPIGANIASPSEPKEANRKKLADMIASRQQQQQQQQQQQQQQQQQQQAQTLAQAQ 1749

Query: 2029 GLKKRVVQVWFQNTRARERKGQFRSTPGGVPSPAVKPPATATPASLPKFNLLLGKVDDGT 2088
               +  +Q   Q   A  +   F                   P  LP F +        T
Sbjct: 1750 AQVQAHLQQELQQQAALIQSQLFN------------------PTLLPHFPMTTE-----T 1786

Query: 2089 GREAPKREAPAFPY--PTATLASGPQPFLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEE 2146
              +  +++   FP+  P+A     P+  LP    A T T   P  LL       +   + 
Sbjct: 1787 LLQLQQQQHLLFPFYIPSAEFQLNPEVSLPVTSGALTLTGTGP-GLLEDLKAQVQVPQQS 1845

Query: 2147 PPKASPESEACSLSAGDLSDSSASSLAEP---------------------ESPGAGGTSG 2185
              +  P+ +   LS       S S+L +P                     E   A G  G
Sbjct: 1846 HQQILPQQQQNQLSIAQ----SHSALLQPSQHPEKKNKLVIKEKEKESQRERDSAEGGEG 1901

Query: 2186 GPGGGTGVPDGMGQRRYR-------TQMSSLQLKIMKACYEAYRTPTMQECEVLGEEIGL 2238
              G    +PD +  +  +       ++ S L  +I     +A    T    E  G E+  
Sbjct: 1902 NTGPKETLPDALKAKEKKELAPGGGSEPSMLPPRIAS---DARGNATKALLENFGFEL-- 1956

Query: 2239 PKRVIQVWFQNARAKEKKAKLQGTAAGSTGGSSEGLLAAQRTDCPYCDVKYDFYVSCRGH 2298
               VIQ         E K K+Q     +  G +      ++ +C  C   +   +  + H
Sbjct: 1957 ---VIQY-------NENKQKVQKKNGKTDQGEN-----LEKLECDSCGKLFSNILILKSH 2001

Query: 2299 LFSRQHL-------AKLKEAVRAQLKSESKCYDLAPAPEAPPALKAPPATTPASMPLGAA 2351
               ++H+        +L+   +       K Y L P    PP    PP   P   PL AA
Sbjct: 2002 ---QEHVHQNYFPFKQLERFAKQYRDHYDKLYPLRPQTPEPP----PPPPPPPPPPLPAA 2054

Query: 2352 PTLPRLAPVL-LSGPALAQPPLGNLAPFNSGPAASSGL---LGLATSVLPTTTVVQT--- 2404
            P  P   P +  S P +  P +    P  S P     +   L + + ++  T  +QT   
Sbjct: 2055 PPQPASTPAIPASAPPITSPTIAPAQP--SVPLTQLSMPMELPIFSPLMMQTMPLQTLPA 2112

Query: 2405 -----AGPGRPLP 2412
                  GP  PLP
Sbjct: 2113 QLPPQLGPVEPLP 2125



 Score = 35.0 bits (79), Expect = 1.0
 Identities = 17/38 (44%), Positives = 19/38 (50%), Gaps = 5/38 (13%)

Query: 2520 PMIPQTLIGLLPNALLQPPPQPPEPTATAPPKPPELPA 2557
            P+ PQT     P     PPP PP P   APP+P   PA
Sbjct: 2031 PLRPQT-----PEPPPPPPPPPPPPLPAAPPQPASTPA 2063



 Score = 34.7 bits (78), Expect = 1.3
 Identities = 32/103 (31%), Positives = 45/103 (43%), Gaps = 9/103 (8%)

Query: 1843 EEEEEVEEEEVEEEQGLE---PPAGPEGPLPEPPDGEELSQAEATKAGGKEPEEKATPSP 1899
            E+   + EE+ EEE  LE    P G +    +   G E  +A   + G     EK    P
Sbjct: 1483 EDHTIIVEEDKEEESDLEDKQSPTGSDSGSVQEDSGSEPKRALPFRKGPNFTMEKFL-DP 1541

Query: 1900 SPAHTCDQCAISFSSQDLLTSH----RRLHFLP-SLQPSAPPQ 1937
            S  + C  C  SF+ +++L  H      LH L  +LQ SA  Q
Sbjct: 1542 SRPYKCTVCKESFTQKNILLVHYNSVSHLHKLKRALQESATGQ 1584



 Score = 33.9 bits (76), Expect = 2.2
 Identities = 52/233 (22%), Positives = 86/233 (36%), Gaps = 47/233 (20%)

Query: 1383 KCTVCRVSYNQSSTLEIHMRSVLHQTRSRGTKTDSKIEGPERSQEEP---KEGETEGEVG 1439
            +CT+C + Y+   ++  H+ S  H ++ + T   S+++  E+   +P   ++   + E+ 
Sbjct: 3025 ECTLCGIKYSARLSVRDHIFSQQHISKVKDT-IGSQLD-KEKEYFDPATVRQLMAQQELD 3082

Query: 1440 TEKKGPDTSGFISGLP--FLSPPPPPLDLHR-FPAPLFTPPVLPPFPLVPESLLKLQQQQ 1496
              KK  +  G  +     F + P   L+L   +PA    PPVL P    P          
Sbjct: 3083 RIKKANEVLGLAAQQQGMFDNTPLQALNLPTAYPALQGIPPVLLPGLNSPS--------- 3133

Query: 1497 LLLPFYLHDLKVGPKLTLAGPAP-VLSLPAATPPPPPQPPKA---ELAEREWERPPMAKE 1552
              LP +           L  P P ++ LP+ T P P  P      + +      P  A+ 
Sbjct: 3134 --LPGFTPS-----NTALTSPKPNLMGLPSTTVPSPGLPTSGLPNKPSSASLSSPTPAQA 3186

Query: 1553 GNEAGPSSPPDPLPNEAARTAAKALLENFGFELVIQYNEGKQAVPPPPTPPPP 1605
                GP  PP     +                   Q  + +Q  PPP   PPP
Sbjct: 3187 TMAMGPQQPPQQQQQQ-------------------QQPQVQQPPPPPAAQPPP 3220



 Score = 33.5 bits (75), Expect = 2.9
 Identities = 26/92 (28%), Positives = 34/92 (36%), Gaps = 13/92 (14%)

Query: 609  PPGLMGPGPPPP-------PGATPTSPPELFQYFGPQ-ALGQPQTPLAGPGLRPDKPLEA 660
            PP    P PPPP       P +TP  P        P  A  QP  PL    +  + P+ +
Sbjct: 2039 PPPPPPPPPPPPLPAAPPQPASTPAIPASAPPITSPTIAPAQPSVPLTQLSMPMELPIFS 2098

Query: 661  QLLLNGFHHVGAPARKFPTSAPGSLSPDAHLP 692
             L++        P +  P   P  L P   LP
Sbjct: 2099 PLMMQTM-----PLQTLPAQLPPQLGPVEPLP 2125



 Score = 32.7 bits (73), Expect = 5.0
 Identities = 53/242 (21%), Positives = 79/242 (32%), Gaps = 38/242 (15%)

Query: 815  SVSPLHLRCNICDFESNSKEKMQLHARGAAHEENSQIYKVRLGAELGLYHCLLCAWETPS 874
            SV P+ LRC +C    N+K  +QLH           + K            L+    TP 
Sbjct: 1247 SVQPM-LRCPLCQDMLNNKIHLQLHLTHLHSVAPDCVEK------------LIMTVTTPE 1293

Query: 875  RLAVLQHLRTPAHRDAQAQRRLQLLQNGPTTEEGLAALQSILSFSHGQLRTPAEVVPAEA 934
             +         A  D      L+     P T E L   ++IL  +  +          ++
Sbjct: 1294 MVMPSSMFLPAAVPDRDGNSNLEEAGKQPETSEDLG--KNILPSASTE----------QS 1341

Query: 935  GNSQPGTIDPEGTGEEPARGCQRLHLKKKKKKKKEWGRASAASKGLCDGGSHPSLTLRPL 994
            G+ +P   DP    E+    C           KK   +    S  L    +        L
Sbjct: 1342 GDLKPSPADPGSVREDSGFICW----------KKGCNQVFKTSAALQTHFNEVHAKRPQL 1391

Query: 995  PICSLQVYC--CPYCSFLSPESSQVRAHTLSQHAVQPKYRCPLCQEQLVGRPALHFHLSH 1052
            P+    VY   C  CS       +++ H+   H ++    C LCQ       AL  HL  
Sbjct: 1392 PVSDRHVYKYRCNQCSLAFKTIEKLQLHS-QYHVIRAATMCCLCQRSFRTFQALKKHLET 1450

Query: 1053 LH 1054
             H
Sbjct: 1451 SH 1452



 Score = 32.7 bits (73), Expect = 5.0
 Identities = 15/39 (38%), Positives = 18/39 (46%)

Query: 1227 TPEASPDPLPEPPLASVEVPDKPSGSPGQPPSPAPSPVP 1265
            TPE  P P P PP      P +P+ +P  P S  P   P
Sbjct: 2036 TPEPPPPPPPPPPPPLPAAPPQPASTPAIPASAPPITSP 2074



 Score = 32.3 bits (72), Expect = 6.5
 Identities = 25/76 (32%), Positives = 34/76 (44%), Gaps = 7/76 (9%)

Query: 2533 ALLQPPPQPPEPTATAPPKPPELPAPGEGEAGEVDELLTGSTGISTVDVTHR---YLCRQ 2589
            +L QPPPQ P P     P P   P+P +     +  L T ST     ++  +   Y C Q
Sbjct: 2479 SLPQPPPQAPPPQC---PLPQSSPSPSQLSHLPLKPLHT-STPQQLANLPPQLIPYQCDQ 2534

Query: 2590 CKMAFDGEAPATAHQR 2605
            CK+AF        HQ+
Sbjct: 2535 CKLAFPSFEHWQEHQQ 2550



 Score = 32.0 bits (71), Expect = 8.5
 Identities = 32/130 (24%), Positives = 48/130 (36%), Gaps = 9/130 (6%)

Query: 2579 VDVTHRYLCRQCKMAFDGEAPATAHQRSFCFFGR------GSGGSMPPPLRVPICT-YHC 2631
            +D +  Y C  CK +F  +     H  S     +       S    P P   P    + C
Sbjct: 1539 LDPSRPYKCTVCKESFTQKNILLVHYNSVSHLHKLKRALQESATGQPEPTSSPDNKPFKC 1598

Query: 2632 LACEVLLSGREALASHLRSSAHRRKAAPPQGGPPISITNAATAASAAVAFAKEEARLPHT 2691
              C V  S    L  H+RS  H+ KA   +       +N  T  S++++ +      P +
Sbjct: 1599 NTCNVAYSQSSTLEIHMRSVLHQTKARAAKLEAASGSSN-GTGNSSSISLSSSTPS-PVS 1656

Query: 2692 DSNPKTTTTS 2701
             S   T TTS
Sbjct: 1657 TSGSNTFTTS 1666



 Score = 32.0 bits (71), Expect = 8.5
 Identities = 45/141 (31%), Positives = 60/141 (42%), Gaps = 22/141 (15%)

Query: 2053 STPGGVPSPAVKPPA-TATPASLPKFNLLLGKVDD--------GTGREAPK-REAP-AFP 2101
            STP  +PS A   PA +A   +   F  L  + ++          G E PK  EAP A P
Sbjct: 2383 STP--MPSQAYSAPAPSANNTASSAFLQLTAEAEELATFNSKTEAGDEKPKLAEAPSAQP 2440

Query: 2102 YPTATLASGPQPFLPPGK--EATTPTPEPPLPLLP-----PPPPSEEEGPEEP-PKASPE 2153
              T      P+P L   +  E  T TP+  LP L      P PP +   P+ P P++SP 
Sbjct: 2441 NQTQEKQGQPKPELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPPPQAPPPQCPLPQSSPS 2500

Query: 2154 -SEACSLSAGDLSDSSASSLA 2173
             S+   L    L  S+   LA
Sbjct: 2501 PSQLSHLPLKPLHTSTPQQLA 2521


>gi|126090663 zinc finger homeodomain 4 [Homo sapiens]
          Length = 3571

 Score =  500 bits (1288), Expect = e-141
 Identities = 303/779 (38%), Positives = 403/779 (51%), Gaps = 98/779 (12%)

Query: 360  AKESPVAAGEAGPDWFPEGQEEDGGLCPPLNQSSPTSKEGGTLPAPVGSPEDPSDPPQPY 419
            A  S  +A  A P     G E+          SS T  + G  P+  G+P  P     P 
Sbjct: 562  ASASKDSATAAHPSEIARGDED----------SSATPHQHGFTPSTPGTP-GPGGDGSPG 610

Query: 420  RLADDYTPAPAAFQGLSLSSHMSLLHSRNSCKTLKCPKCNWHYKYQQTLDVHMREKHPES 479
               +            SL  HM+++HSRNSCKTLKCPKCNWHYKYQQTL+ HM+EKHPE 
Sbjct: 611  SGIECPKCDTVLGSSRSLGGHMTMMHSRNSCKTLKCPKCNWHYKYQQTLEAHMKEKHPEP 670

Query: 480  NSHCSYCSAGGAHPRLARGESYNCGYKPYRCDVCNYSTTTKGNLSIHMQSDKHLANLQGF 539
               C YC  G  HPRLARGESY CGYKP+RC+VCNYSTTTKGNLSIHMQSDKHL N+Q  
Sbjct: 671  GGSCVYCKTGQPHPRLARGESYTCGYKPFRCEVCNYSTTTKGNLSIHMQSDKHLNNVQNL 730

Query: 540  QAGPG----GQGSP-PEASLP--PSAGDKEPKTKSSWQCKVCSYETNISRNLRIHMTSEK 592
            Q G G    G  +P P  SL    +    +PK K +W+C+VC YETN++RNLRIHMTSEK
Sbjct: 731  QNGNGEQVFGHSAPAPNTSLSGCGTPSPSKPKQKPTWRCEVCDYETNVARNLRIHMTSEK 790

Query: 593  HMQNVLMLHQ-------GLPLGLPPGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQT 645
            HM N+++L Q        L LGL P                +  EL+QY+  Q +G    
Sbjct: 791  HMHNMMLLQQNMKQIQHNLHLGLAP----------------AEAELYQYYLAQNIGL--- 831

Query: 646  PLAGPGLRPDKPLEAQLLLNGFHHVGAPARKFPTSAPGSLSPDAHLPPSQLLGSSSDSLP 705
                 G++ + P + QL++N F    A A      APG             LG  S    
Sbjct: 832  ----TGMKLENPADPQLMINPFQLDPATAAAL---APG-------------LGELS---- 867

Query: 706  TSPPPDDSLSLKVFRCLVCQAFSTDSLELLLYHCSIGRSLPEAEWKEVAGDTHRCKLCCY 765
               P     +LK+F+C VC  F++DSLE L  H S  RSLPE EW+ V GD ++CKLC Y
Sbjct: 868  ---PYISDPALKLFQCAVCNKFTSDSLEALSVHVSSERSLPEEEWRAVIGDIYQCKLCNY 924

Query: 766  GTQLKANFQLHLKTDKHAQKYQLAAHLREGGGAMGTPSPA-SLGDGAPYGSVSPLHLRCN 824
             TQLKANFQLH KTDKH QKYQL AH++EGG +        ++G        +P+HL+CN
Sbjct: 925  NTQLKANFQLHCKTDKHMQKYQLVAHIKEGGKSNEWRLKCIAIG--------NPVHLKCN 976

Query: 825  ICDFESNSKEKMQLHARGAAHEENSQIYK------VRLGAELGLYHCLLCAWETPSRLAV 878
             CD+ +NS +K++LH     HE   ++YK        +  E   Y+C +C + T  +L +
Sbjct: 977  ACDYYTNSVDKLRLHTTNHRHEAALKLYKHLQKQEGAVNPESCYYYCAVCDYTTKVKLNL 1036

Query: 879  LQHLRTPAHRDAQAQRRLQLLQNGPTTEE-GLAALQSILSFSHGQLRTPA------EVVP 931
            +QH+R+  H+  +  R+LQL Q G   EE  L+ +  +      +L T +      +   
Sbjct: 1037 VQHVRSVKHQQTEGLRKLQLHQQGLAPEEDNLSEIFFVKDCPPNELETASLGARTCDDDL 1096

Query: 932  AEAGNSQPGTIDPEGTGEEPARGCQRLHLKKKKKKKKEWGRASAASKGLCDGGSHPSLTL 991
             E      G I P    E+  +        + K   K+    +  ++ L         T 
Sbjct: 1097 TEQHEEAEGAIKPTAVAEDDEKDTSERDNSEGKNSNKDSVSVAGGTQPLLLAKEEDVATK 1156

Query: 992  RPLP-----ICSLQVYCCPYCSFLSPESSQVRAHTLSQHAVQPKYRCPLCQEQLVGRPAL 1046
            R  P      C  Q Y CPYC++ S + S+++ H LSQH+VQP   CPLCQ+ L  +  L
Sbjct: 1157 RSKPTEDNKFCHEQFYQCPYCNYNSRDQSRIQMHVLSQHSVQPVICCPLCQDVLSNKMHL 1216

Query: 1047 HFHLSHLHNVVPECVEKLLLVVSTGWVRTVQQDLIRAVQEGRKRQGYSGRCMCWGQGAF 1105
              HL+HLH+V P+CVEKLL+ V    V      L+ A    +  +         G G +
Sbjct: 1217 QLHLTHLHSVSPDCVEKLLMTVPVPDVMMPNSMLLPAAASEKSERDTPAAVTAEGSGKY 1275



 Score =  270 bits (691), Expect = 1e-71
 Identities = 204/641 (31%), Positives = 283/641 (44%), Gaps = 140/641 (21%)

Query: 2167 SSASSLAEPESPGAGGTSGGPGGGTGVPDGMGQRRYRTQMSSLQLKIMKACYEAYRTPTM 2226
            S  SS+A+P SP   G+S      +   D  G +R+RTQMS+LQLK++KAC+  YRTPTM
Sbjct: 2854 SETSSIADPSSPNPFGSSNPFKSKSN--DRPGHKRFRTQMSNLQLKVLKACFSDYRTPTM 2911

Query: 2227 QECEVLGEEIGLPKRVIQVWFQNARAKEKKAKLQ-GTAAGSTGGSSEGLLAAQRTDCPYC 2285
            QECE+LG EIGLPKRV+QVWFQNARAKEKK K+  G       G +EG     + +C  C
Sbjct: 2912 QECEMLGNEIGLPKRVVQVWFQNARAKEKKFKINIGKPFMINQGGTEGT----KPECTLC 2967

Query: 2286 DVKYDFYVSCRGHLFSRQHLAKLKEAVRAQLKSES---------------------KCYD 2324
             VKY   +S R H+FS+QH++K++E V +QL  E                      K  D
Sbjct: 2968 GVKYSARLSIRDHIFSKQHISKVRETVGSQLDREKDYLAPTTVRQLMAQQELDRIKKASD 3027

Query: 2325 LAPAPEAPPALKAPPATTPASMPLGAAPTLPRLAPVLLSGPALAQPPLGNLAPFNSGPAA 2384
            +       P +    +    S+P  A P LP L PVLL G        G     N+    
Sbjct: 3028 VLGLTVQQPGMMDSSSLHGISLPT-AYPGLPGLPPVLLPGMNGPSSLPGFPQNSNTLTPP 3086

Query: 2385 SSGLLGLATSVLPTTTVVQTAGPGRPLPQRPMPDQTNTSTAGTTDPVPGPPTEPLGDKVS 2444
             +G+LG  TS   +  +  ++ P +PL Q P P            P P PP+  L  + +
Sbjct: 3087 GAGMLGFPTSATSSPALSLSSAPTKPLLQTPPPPPP---------PPPPPPSSSLSGQQT 3137

Query: 2445 SERKPVAGPTSSSNDALKNLKA--LKTTVP------------------------------ 2472
             ++   +    +  + +K +K   L+ T P                              
Sbjct: 3138 EQQNKESEKKQTKPNKVKKIKEEELEATKPEKHPKKEEKISSALSVLGKVVGETHVDPIQ 3197

Query: 2473 -------------ALLGGQFLPFPLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMN 2519
                         + +GGQFLP+ +P       P + G  +QG YF  + GM+  LFP  
Sbjct: 3198 LQALQNAIAGDPASFIGGQFLPYFIPGFASYFTPQLPGT-VQGGYFPPVCGMES-LFPYG 3255

Query: 2520 PMIPQTLIGLLPNALLQP-------------------PPQPPEPTATAPPKPPELPAPGE 2560
            P +PQTL GL P ALLQ                      Q  +P      K         
Sbjct: 3256 PTMPQTLAGLSPGALLQQYQQYQQNLQESLQKQQKQQQEQQQKPVQAKTSKVESDQPQNS 3315

Query: 2561 GEAGEVDELLTGSTGISTVD------------------VTHRYLCRQCKMAFDGEAPATA 2602
             +A E  E  + +T  +  +                  V + ++CR+C+M F  E  A  
Sbjct: 3316 NDASETKEDKSTATESTKEEPQLESKSADFSDTYVVPFVKYEFICRKCQMMFTDEDAAVN 3375

Query: 2603 HQRSFCFFGRGSGGSMPPPLRVPICTYHCLACEVLLSGREALASHLRSSAHRRKAAPPQG 2662
            HQ+SFC+FG+         LRVP+  Y CLAC+V +SG EAL+ HL+SS H+ K      
Sbjct: 3376 HQKSFCYFGQPLIDPQETVLRVPVSKYQCLACDVAISGNEALSQHLQSSLHKEK------ 3429

Query: 2663 GPPISITNAATAASAAVAFAKEEAR-LPHTDSNPKTTTTST 2702
                           A+  AKE  R LPH+  +P   TTST
Sbjct: 3430 -----------TIKQAMRNAKEHVRLLPHSVCSPNPNTTST 3459



 Score =  228 bits (581), Expect = 6e-59
 Identities = 211/738 (28%), Positives = 285/738 (38%), Gaps = 209/738 (28%)

Query: 1455 PFLSPPPPPLDLHRFPAPLFTPPVLPPFPLVPESLLKLQQQQLLLPFYLHDLKVGPKLTL 1514
            P   PPPPP            PP LPP P  P S+                   GP    
Sbjct: 1955 PETPPPPPP------------PPPLPPAPPQPSSM-------------------GPVKIP 1983

Query: 1515 AGPAPVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPSSPPDPLPNEAARTAA 1574
               +  L  P  TPPPPP PP           PP         P  PP P P+   +   
Sbjct: 1984 NTVSTPLQAPPPTPPPPPPPPP----------PP---------PPPPPPPPPSAPPQVQL 2024

Query: 1575 KALLENFGFELVIQYNEGKQAVPPPPTP--PPPEALGGGDKLACGACGKLFSNMLILKTH 1632
               L+   F  ++       A+PP      P  +AL       C     L  N L    H
Sbjct: 2025 PVSLDLPLFPSIMMQPVQHPALPPQLALQLPQMDALSADLTQLCQQQLGLDPNFL---RH 2081

Query: 1633 EEHVHRRFL----PFEALSRYAAQFRKSYDSLYPPLAEPP----------------KPPD 1672
             +    R        + L  Y        +     +AE                  K   
Sbjct: 2082 SQFKRPRTRITDDQLKILRAYFDINNSPSEEQIQEMAEKSGLSQKVIKHWFRNTLFKERQ 2141

Query: 1673 GSLDSPVPHLGPPFLVPEPEAGGTRAPEERSRAGGHWPIEEEESSRGNLPPLVPAGRRFS 1732
             + DSP     PP  V E                    I+ + +S  +        +R S
Sbjct: 2142 RNKDSPYNFSNPPITVLEDIR-----------------IDPQPTSLEHYKSDASFSKRSS 2184

Query: 1733 RTKFTEFQTQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARK---NAC 1789
            RT+FT++Q + LQ FF+T+AYPKD E+E+L+++L L +RV+VVWFQNARQKARK   N  
Sbjct: 2185 RTRFTDYQLRVLQDFFDTNAYPKDDEIEQLSTVLNLPTRVIVVWFQNARQKARKSYENQA 2244

Query: 1790 EGGSMPTGGGTGGAS--------GCRRCHATFSCVFELVRHLKK-CYDDQTLEEEEE--- 1837
            E         T             C++C+  F  +F+L+ H KK CY D+  + ++E   
Sbjct: 2245 ETKDNEKRELTNERYIRTSNMQYQCKKCNVVFPRIFDLITHQKKQCYKDEDDDAQDESQT 2304

Query: 1838 ------------------------------------------------EAERGEEEEEVE 1849
                                                            E E+   + E  
Sbjct: 2305 EDSMDATDQVVYKHCTVSGQTDAAKNAAAPAASSGSGTSTPLIPSPKPEPEKTSPKPEYP 2364

Query: 1850 EEEVEEEQGLEPPAGPEGPLPEPPDGEELSQAEATKAG------------GKEPEEKATP 1897
             E+ ++     P  G +  LP      +  QA   +              G+ P    TP
Sbjct: 2365 AEKPKQSDPSPPSQGTKPALPLASTSSDPPQASTAQPQPQPQPPKQPQLIGRPPSASQTP 2424

Query: 1898 SPSPA------------------HTCDQCAISFSSQDLLTSHRRLHFLPS----LQPSAP 1935
             PS                    + CDQC ++F + +L   H+ +HFL +    L     
Sbjct: 2425 VPSSPLQISMTSLQNSLPPQLLQYQCDQCTVAFPTLELWQEHQHMHFLAAQNQFLHSPFL 2484

Query: 1936 PQLLDLPLLVFGERNPLV---------------AATSPMPGPP-----LKRKHEDGSLSP 1975
             + +D+P ++F   NPL+               A++S    P      LKRK +D   + 
Sbjct: 2485 ERPMDMPYMIFDPNNPLMTGQLLGSSLTQMPPQASSSHTTAPTTVAASLKRKLDDKEDNN 2544

Query: 1976 TGSEAGGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVV 2035
               + GG    +  RDKRLRTTI PEQLEILY  Y+ DSNPTRKMLD I+ EVGLKKRVV
Sbjct: 2545 CSEKEGGNSGEDQHRDKRLRTTITPEQLEILYEKYLLDSNPTRKMLDHIAREVGLKKRVV 2604

Query: 2036 QVWFQNTRARERKGQFRS 2053
            QVWFQNTRARERKGQFR+
Sbjct: 2605 QVWFQNTRARERKGQFRA 2622



 Score =  186 bits (473), Expect = 2e-46
 Identities = 118/308 (38%), Positives = 158/308 (51%), Gaps = 65/308 (21%)

Query: 1275 APPPTMAEEEEGTTGELR---------SAEPAPADS-----------RHPLTYRKTTNFA 1314
            A   TM++++ G   E+           A P  +DS           +  L +RK  NF 
Sbjct: 1426 AESETMSQDDHGLEQEMEREYEVDHEGKASPVGSDSSSIPDDMGSEPKRTLPFRKGPNFT 1485

Query: 1315 LDKFLDPARPYKCTVCKESFTQKNILLVHYNSVSHLHKMKKAAIDPSAPARGEAGAPPTT 1374
            ++KFLDP+RPYKCTVCKESFTQKNILLVHYNSVSHLHK+KK   + S+P       P  T
Sbjct: 1486 MEKFLDPSRPYKCTVCKESFTQKNILLVHYNSVSHLHKLKKVLQEASSP------VPQET 1539

Query: 1375 TAATD-KPFKCTVCRVSYNQSSTLEIHMRSVLHQTRSRGTKTD------------SKIEG 1421
             + TD KP+KC++C V+Y+QSSTLEIHMRSVLHQT++R  K +            + +  
Sbjct: 1540 NSNTDNKPYKCSICNVAYSQSSTLEIHMRSVLHQTKARAAKLEPSGHVAGGHSIAANVNS 1599

Query: 1422 PERSQEE--------PKEGETEGEVGTEKKGPDTSGFISGLPFLSPPPPPLDLHR----- 1468
            P +   +         K+   + +   +K+ PD    IS  P   PP  P  +       
Sbjct: 1600 PGQGMLDSMSLAAVNSKDTHLDAKELNKKQTPD---LISAQPAHHPPQSPAQIQMQLQHE 1656

Query: 1469 -------FPAPLFTPPVLPPFPLVPESLLKLQQQQLLLPFYL--HDLKVGPKLTLAGPAP 1519
                   F      P  LP FP+ PE+LL+ QQ Q L PFY+   +  +GP L L G A 
Sbjct: 1657 LQQQAAFFQPQFLNPAFLPHFPMTPEALLQFQQPQFLFPFYIPGTEFSLGPDLGLPGSA- 1715

Query: 1520 VLSLPAAT 1527
               +P  T
Sbjct: 1716 TFGMPGMT 1723



 Score =  130 bits (328), Expect = 1e-29
 Identities = 79/177 (44%), Positives = 100/177 (56%), Gaps = 12/177 (6%)

Query: 1532 PQPPKAE-LAEREWERPPM-AKEGNEAGPSSPPDPLPNEAARTAAKALLENFGFELVIQY 1589
            P+ PK E ++E E  +     K+     PS PP  + + A   AAKALLENFGFELVIQY
Sbjct: 1820 PEKPKQEFISEGEGLKEGKDTKKQKSLEPSIPPPRIASGARGNAAKALLENFGFELVIQY 1879

Query: 1590 NEGKQAVPPPPTPPPPEALGGGDKLACGACGKLFSNMLILKTHEEHVHRRFLPFEALSRY 1649
            NE +Q V         E     DKL CG CGKLFSN+LILK+H+EHVH +F P+ AL ++
Sbjct: 1880 NENRQKVQKKGKSGEGE---NTDKLECGTCGKLFSNVLILKSHQEHVHGQFFPYAALEKF 1936

Query: 1650 AAQFRKSYDSLYP-----PLAEPPKPPDGSLD--SPVPHLGPPFLVPEPEAGGTRAP 1699
            A Q+R++YD LYP     P   PP PP   L    P P    P  +P   +   +AP
Sbjct: 1937 ARQYREAYDKLYPISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAP 1993



 Score = 65.1 bits (157), Expect = 9e-10
 Identities = 56/189 (29%), Positives = 82/189 (43%), Gaps = 41/189 (21%)

Query: 2147 PPKAS------PESEACSLSAGDLSDSSASSLAEPESPGAGGTSGGPGGGTGVPDGMGQR 2200
            PP+AS      P + A SL    L D   ++ +E E    GG SG         D    +
Sbjct: 2515 PPQASSSHTTAPTTVAASLKR-KLDDKEDNNCSEKE----GGNSG--------EDQHRDK 2561

Query: 2201 RYRTQMSSLQLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAKLQ 2260
            R RT ++  QL+I+   Y     PT +  + +  E+GL KRV+QVWFQN RA+E+K + +
Sbjct: 2562 RLRTTITPEQLEILYEKYLLDSNPTRKMLDHIAREVGLKKRVVQVWFQNTRARERKGQFR 2621

Query: 2261 GTAAGSTGGSSEGLLAAQRTDCPYCDVKYDFYVSCRGHLFSRQHLAKLKEAVRAQLKSES 2320
                           A     CP+C   +    +   H+ SR H  + K+A         
Sbjct: 2622 AVGP-----------AQSHKRCPFCRALFKAKSALESHIRSR-HWNEGKQA--------- 2660

Query: 2321 KCYDLAPAP 2329
              Y L P+P
Sbjct: 2661 -GYSLPPSP 2668



 Score = 60.1 bits (144), Expect = 3e-08
 Identities = 53/203 (26%), Positives = 85/203 (41%), Gaps = 18/203 (8%)

Query: 2054 TPGGVPSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQP 2113
            TP   P P   PPA   P+S+       G V        P +  P  P P       P P
Sbjct: 1957 TPPPPPPPPPLPPAPPQPSSM-------GPVKIPNTVSTPLQAPPPTPPPPPPPPPPPPP 2009

Query: 2114 FLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESEACSLSAGDLSDSSASSLA 2173
              PP   +  P  + P+ L  P  PS    P + P A P   A  L   D   +  + L 
Sbjct: 2010 PPPPPPPSAPPQVQLPVSLDLPLFPSIMMQPVQHP-ALPPQLALQLPQMDALSADLTQLC 2068

Query: 2174 EPESPGAGGTSGGPGGGTGVPDGMGQRRYRTQMSSLQLKIMKACYEAYRTPTMQECEVLG 2233
            + +           G           +R RT+++  QLKI++A ++   +P+ ++ + + 
Sbjct: 2069 QQQL----------GLDPNFLRHSQFKRPRTRITDDQLKILRAYFDINNSPSEEQIQEMA 2118

Query: 2234 EEIGLPKRVIQVWFQNARAKEKK 2256
            E+ GL ++VI+ WF+N   KE++
Sbjct: 2119 EKSGLSQKVIKHWFRNTLFKERQ 2141



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 31/78 (39%), Positives = 45/78 (57%), Gaps = 5/78 (6%)

Query: 1971 GSLSPTGSEAGGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGL 2030
            GS +P  S++      + P  KR RT +   QL++L   +     PT +  + +  E+GL
Sbjct: 2869 GSSNPFKSKSN-----DRPGHKRFRTQMSNLQLKVLKACFSDYRTPTMQECEMLGNEIGL 2923

Query: 2031 KKRVVQVWFQNTRARERK 2048
             KRVVQVWFQN RA+E+K
Sbjct: 2924 PKRVVQVWFQNARAKEKK 2941



 Score = 53.1 bits (126), Expect = 4e-06
 Identities = 41/135 (30%), Positives = 57/135 (42%), Gaps = 11/135 (8%)

Query: 1692 EAGGTRAPEERSRAGGHWPIEEEESSRGNLPPLVPAGRRFSRTKFTEFQTQALQSFFETS 1751
            E      P   +  G   P + + + R       P  +RF RT+ +  Q + L++ F   
Sbjct: 2855 ETSSIADPSSPNPFGSSNPFKSKSNDR-------PGHKRF-RTQMSNLQLKVLKACFSDY 2906

Query: 1752 AYPKDGEVERLASLLGLASRVVVVWFQNARQKARKNACEGGS--MPTGGGTGGAS-GCRR 1808
              P   E E L + +GL  RVV VWFQNAR K +K     G   M   GGT G    C  
Sbjct: 2907 RTPTMQECEMLGNEIGLPKRVVQVWFQNARAKEKKFKINIGKPFMINQGGTEGTKPECTL 2966

Query: 1809 CHATFSCVFELVRHL 1823
            C   +S    +  H+
Sbjct: 2967 CGVKYSARLSIRDHI 2981



 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 72/309 (23%), Positives = 116/309 (37%), Gaps = 46/309 (14%)

Query: 1773 VVVWFQNARQKARKNACEGGSMPTGGGTGGASGCRRCHATFSCVFELVRHLKKCYDDQTL 1832
            +V+ +   RQK +K    G      G       C  C   FS V  L  H +  +     
Sbjct: 1875 LVIQYNENRQKVQKKGKSGE-----GENTDKLECGTCGKLFSNVLILKSHQEHVHGQFFP 1929

Query: 1833 EEEEEEAERGEEEEEVEEEEVEEEQGLEPPAGPEGPL--PEPPDGEELSQAE-----ATK 1885
                E+  R   E   +   +       PP  P  P   P PP    +   +     +T 
Sbjct: 1930 YAALEKFARQYREAYDKLYPISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTP 1989

Query: 1886 AGGKEPEEKATPSPSPAHTCDQCAISFSSQDLLTSHRRLHFLPSLQPSAPPQL-----LD 1940
                 P     P P P                          P   PSAPPQ+     LD
Sbjct: 1990 LQAPPPTPPPPPPPPPPPPPPP--------------------PPPPPSAPPQVQLPVSLD 2029

Query: 1941 LPLLVFGERNPLVAATSPMPGPPLKRKHEDGSLSPTGSEAGGGGEGEPP------RDKRL 1994
            LPL       P+     P P   L+    D +LS   ++      G  P      + KR 
Sbjct: 2030 LPLFPSIMMQPVQHPALP-PQLALQLPQMD-ALSADLTQLCQQQLGLDPNFLRHSQFKRP 2087

Query: 1995 RTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQNTRARERKGQFRST 2054
            RT I  +QL+IL  ++  +++P+ + +  ++E+ GL ++V++ WF+NT  +ER+ + + +
Sbjct: 2088 RTRITDDQLKILRAYFDINNSPSEEQIQEMAEKSGLSQKVIKHWFRNTLFKERQ-RNKDS 2146

Query: 2055 PGGVPSPAV 2063
            P    +P +
Sbjct: 2147 PYNFSNPPI 2155



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 92/450 (20%), Positives = 146/450 (32%), Gaps = 73/450 (16%)

Query: 1382 FKCTVCRVSYNQSSTLEIHMRSVLHQTRSRGTKTDSKIEGPERSQEEP--KEGETEGEVG 1439
            ++C  C V + +   L  H +   ++      + +S+ E    + ++   K     G+  
Sbjct: 2267 YQCKKCNVVFPRIFDLITHQKKQCYKDEDDDAQDESQTEDSMDATDQVVYKHCTVSGQTD 2326

Query: 1440 TEKKGPD---TSGFISGLPFLSPPPPPLDLHRFPAPLFTPPVLPPFPLVPESLLKLQQQQ 1496
              K       +SG  +  P +  P P             P    P P  P    K     
Sbjct: 2327 AAKNAAAPAASSGSGTSTPLIPSPKPE------------PEKTSPKPEYPAEKPKQSD-- 2372

Query: 1497 LLLPFYLHDLKVGPKLTLAGPAPVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEA 1556
                         P     G  P L L A+T   PPQ   A+   +   +PP   +    
Sbjct: 2373 -------------PSPPSQGTKPALPL-ASTSSDPPQASTAQ--PQPQPQPPKQPQLIGR 2416

Query: 1557 GPSSPPDPLPNEAARTAAKALLENFGFELVIQYNEGKQAVPPPPTPPPPEALGGGDKLAC 1616
             PS+   P+P+   + +  +L  +                       PP+ L    +  C
Sbjct: 2417 PPSASQTPVPSSPLQISMTSLQNSL----------------------PPQLL----QYQC 2450

Query: 1617 GACGKLFSNMLILKTHEEHVHRRFLPFEALSRYAAQFRKSYDSLYPPLAEPPKP--PDGS 1674
              C   F     L+  +EH H  FL  +    ++    +  D  Y  + +P  P      
Sbjct: 2451 DQCTVAFPT---LELWQEHQHMHFLAAQNQFLHSPFLERPMDMPYM-IFDPNNPLMTGQL 2506

Query: 1675 LDSPVPHLGPPFLVPEPEAGGTRAPEERSRAGGHWPIEEEESSRGNLPPLVPAGRRFSRT 1734
            L S +  + P        A  T A   + +          E   GN        +R  RT
Sbjct: 2507 LGSSLTQMPPQASSSHTTAPTTVAASLKRKLDDKEDNNCSEKEGGNSGEDQHRDKRL-RT 2565

Query: 1735 KFTEFQTQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARKNACEGGSM 1794
              T  Q + L   +   + P    ++ +A  +GL  RVV VWFQN R + RK     G  
Sbjct: 2566 TITPEQLEILYEKYLLDSNPTRKMLDHIAREVGLKKRVVQVWFQNTRARERK-----GQF 2620

Query: 1795 PTGGGTGGASGCRRCHATFSCVFELVRHLK 1824
               G       C  C A F     L  H++
Sbjct: 2621 RAVGPAQSHKRCPFCRALFKAKSALESHIR 2650



 Score = 49.3 bits (116), Expect = 5e-05
 Identities = 88/377 (23%), Positives = 141/377 (37%), Gaps = 57/377 (15%)

Query: 2199 QRRYRTQMSSLQLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAK----- 2253
            +R  RT+ +  QL++++  ++    P   E E L   + LP RVI VWFQNAR K     
Sbjct: 2181 KRSSRTRFTDYQLRVLQDFFDTNAYPKDDEIEQLSTVLNLPTRVIVVWFQNARQKARKSY 2240

Query: 2254 EKKAKLQGTAAGSTGGSSEGLLAAQRTDCPYCDVKYDFYVSCRGHLFSR---------QH 2304
            E +A+ +               +  +  C  C+V +        H   +         Q 
Sbjct: 2241 ENQAETKDNEKRELTNERYIRTSNMQYQCKKCNVVFPRIFDLITHQKKQCYKDEDDDAQD 2300

Query: 2305 LAKLKEAVRAQLKSESKCYDLAPAPEAPPALKAPPATTPASMPLGAAPTLPRLAPVLLSG 2364
             ++ ++++ A  +   K   ++   +A     AP A++ +       P+ P+  P   S 
Sbjct: 2301 ESQTEDSMDATDQVVYKHCTVSGQTDAAKNAAAPAASSGSGTSTPLIPS-PKPEPEKTS- 2358

Query: 2365 PALAQPPLGNLAPFNSGPAASSGLLGLATSVLPTTTVVQTAGPGRPLPQRPMPDQTNTST 2424
                +P      P  S P+  S                Q   P  PL      D    ST
Sbjct: 2359 ---PKPEYPAEKPKQSDPSPPS----------------QGTKPALPLAS-TSSDPPQAST 2398

Query: 2425 AGTTDPVPGPPTEP--LGDKVSSERKPV-AGPTSSSNDALKNLKALKTTVPALLGGQ--- 2478
            A    P P PP +P  +G   S+ + PV + P   S  +L+N     +  P LL  Q   
Sbjct: 2399 A-QPQPQPQPPKQPQLIGRPPSASQTPVPSSPLQISMTSLQN-----SLPPQLLQYQCDQ 2452

Query: 2479 -FLPFPLPPAGGTAPPAVF----GPQLQGAYFQQLYGMKKGLF-PMNPMIPQTLIGLLPN 2532
              + FP            F       L   + ++   M   +F P NP++   L+G   +
Sbjct: 2453 CTVAFPTLELWQEHQHMHFLAAQNQFLHSPFLERPMDMPYMIFDPNNPLMTGQLLG---S 2509

Query: 2533 ALLQPPPQPPEPTATAP 2549
            +L Q PPQ      TAP
Sbjct: 2510 SLTQMPPQASSSHTTAP 2526



 Score = 47.4 bits (111), Expect = 2e-04
 Identities = 47/189 (24%), Positives = 71/189 (37%), Gaps = 23/189 (12%)

Query: 1323 RPYKCTVCKESFTQKNILLVHYNSVSHLHKMKKAAIDPSAPARGEAGAPPTT------TA 1376
            +P++C VC  S T K  L +H  S  HL+ ++           G +   P T      T 
Sbjct: 697  KPFRCEVCNYSTTTKGNLSIHMQSDKHLNNVQNLQNGNGEQVFGHSAPAPNTSLSGCGTP 756

Query: 1377 ATDKP-----FKCTVCRVSYNQSSTLEIHMRSVLHQTRSRGTKTDSK-IEGPERSQEEPK 1430
            +  KP     ++C VC    N +  L IHM S  H       + + K I+        P 
Sbjct: 757  SPSKPKQKPTWRCEVCDYETNVARNLRIHMTSEKHMHNMMLLQQNMKQIQHNLHLGLAPA 816

Query: 1431 EGETEGEVGTEKKGPDTSGFISGLPFLSPPPPPLDLHRFPAPLFTPPVLPP-----FPLV 1485
            E E       +  G      ++G+   +P  P L ++ F     T   L P      P +
Sbjct: 817  EAELYQYYLAQNIG------LTGMKLENPADPQLMINPFQLDPATAAALAPGLGELSPYI 870

Query: 1486 PESLLKLQQ 1494
             +  LKL Q
Sbjct: 871  SDPALKLFQ 879



 Score = 46.6 bits (109), Expect = 3e-04
 Identities = 71/323 (21%), Positives = 107/323 (33%), Gaps = 41/323 (12%)

Query: 380  EEDGGLCPPLNQSSPTSKEGGTLPAPVGSPEDPSDPPQPYRLADDYTPAPAAFQGLSLSS 439
            ++D GL   + +      EG    +PVGS  D S  P      DD    P          
Sbjct: 1433 QDDHGLEQEMEREYEVDHEGKA--SPVGS--DSSSIP------DDMGSEPKRTLPFRKGP 1482

Query: 440  HMSLLHSRNSCKTLKCPKCNWHYKYQQTLDVHMREKHPESNSHCSYCSAGGAHPRLARGE 499
            + ++    +  +  KC  C   +  +  L VH       S+ H        A   + +  
Sbjct: 1483 NFTMEKFLDPSRPYKCTVCKESFTQKNILLVHYNSV---SHLHKLKKVLQEASSPVPQET 1539

Query: 500  SYNCGYKPYRCDVCNYSTTTKGNLSIHMQSDKHLANLQGFQAGPGGQGSPPEASLPPSAG 559
            + N   KPY+C +CN + +    L IHM+S  H    +  +  P G  +   +       
Sbjct: 1540 NSNTDNKPYKCSICNVAYSQSSTLEIHMRSVLHQTKARAAKLEPSGHVAGGHSIAANVNS 1599

Query: 560  DKEPKTKSSWQCKVCSYETNI-SRNLRIHMTSEKHMQNVLMLHQGLPLGLPPGLMGPGPP 618
              +    S     V S +T++ ++ L    T                    P L+   P 
Sbjct: 1600 PGQGMLDSMSLAAVNSKDTHLDAKELNKKQT--------------------PDLISAQPA 1639

Query: 619  PPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRPDKPLEAQLLLNGFHHVGAPARKFP 678
              P  +P       Q+   Q     Q     P   P  P+  + LL        P   FP
Sbjct: 1640 HHPPQSPAQIQMQLQHELQQQAAFFQPQFLNPAFLPHFPMTPEALL----QFQQPQFLFP 1695

Query: 679  TSAPG---SLSPDAHLPPSQLLG 698
               PG   SL PD  LP S   G
Sbjct: 1696 FYIPGTEFSLGPDLGLPGSATFG 1718



 Score = 45.4 bits (106), Expect = 7e-04
 Identities = 60/226 (26%), Positives = 88/226 (38%), Gaps = 29/226 (12%)

Query: 1352 KMKKAAIDPSAPARGEAGAPPTTTAATDKPFKCTVCRVSYNQSSTLEIHMRSVLHQTRSR 1411
            K KK  I+   P     G    T     KP +CT+C V Y+   ++  H+ S  H ++ R
Sbjct: 2938 KEKKFKINIGKPFMINQGGTEGT-----KP-ECTLCGVKYSARLSIRDHIFSKQHISKVR 2991

Query: 1412 GTKTDSKIEGPERSQEEP---KEGETEGEVGTEKKGPDTSGFI---------SGLPFLSP 1459
             T   S+++  E+    P   ++   + E+   KK  D  G           S L  +S 
Sbjct: 2992 ET-VGSQLDR-EKDYLAPTTVRQLMAQQELDRIKKASDVLGLTVQQPGMMDSSSLHGISL 3049

Query: 1460 PPPPLDLHRFPAPLFT----PPVLPPFPLVPESLLKLQQQQLLLPFYLHDLKVGPKLTL- 1514
            P     L   P  L      P  LP FP    +L       L  P         P L+L 
Sbjct: 3050 PTAYPGLPGLPPVLLPGMNGPSSLPGFPQNSNTLTPPGAGMLGFPT---SATSSPALSLS 3106

Query: 1515 -AGPAPVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPS 1559
             A   P+L  P   PPPPP PP + L+ ++ E+     E  +  P+
Sbjct: 3107 SAPTKPLLQTPPPPPPPPPPPPSSSLSGQQTEQQNKESEKKQTKPN 3152



 Score = 35.8 bits (81), Expect = 0.59
 Identities = 21/65 (32%), Positives = 25/65 (38%), Gaps = 10/65 (15%)

Query: 1227 TPEASPDPLPEPPL----------ASVEVPDKPSGSPGQPPSPAPSPVPEPDAQAEDVAP 1276
            +PE  P P P PPL            V++P+  S     PP   P P P P        P
Sbjct: 1954 SPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPPPPPPP 2013

Query: 1277 PPTMA 1281
            PP  A
Sbjct: 2014 PPPSA 2018



 Score = 35.4 bits (80), Expect = 0.77
 Identities = 59/266 (22%), Positives = 102/266 (38%), Gaps = 43/266 (16%)

Query: 2120 EATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPE-----SEACSLSAGDLSDSSASSLAE 2174
            +AT P  +P      PPPP +++  +       E     S  C +     S   A  ++E
Sbjct: 1759 QATQPQLQPQKQQQQPPPPQQQQQQQASKLLKQEQSNIVSADCQIMKDVPSYKEAEDISE 1818

Query: 2175 -PESPGAGGTSGGPGGGTGVPDGMGQRRYRTQMSSLQLKIMKACYEAYRTPTMQECEVLG 2233
             PE P     S G G    + +G   ++ ++   S+    + +             + L 
Sbjct: 1819 KPEKPKQEFISEGEG----LKEGKDTKKQKSLEPSIPPPRIASGARG------NAAKALL 1868

Query: 2234 EEIGLPKRVIQVWFQNARAKEKKAKLQGTAAGSTGGSSEGLLAAQRTDCPYCDVKYDFYV 2293
            E  G  + VIQ + +N +  +KK K          G  E      + +C  C   +   +
Sbjct: 1869 ENFGF-ELVIQ-YNENRQKVQKKGK---------SGEGEN---TDKLECGTCGKLFSNVL 1914

Query: 2294 SCRGHLFSRQHL-------AKLKEAVRAQLKSESKCYDLAPA-PEAPPALKAPPATTPAS 2345
              + H   ++H+       A L++  R   ++  K Y ++P+ PE PP    PP   P +
Sbjct: 1915 ILKSH---QEHVHGQFFPYAALEKFARQYREAYDKLYPISPSSPETPPP-PPPPPPLPPA 1970

Query: 2346 MPLGAAPTLPRLAPVLLSGPALAQPP 2371
             P  ++   P   P  +S P  A PP
Sbjct: 1971 PPQPSSMG-PVKIPNTVSTPLQAPPP 1995



 Score = 35.4 bits (80), Expect = 0.77
 Identities = 23/69 (33%), Positives = 28/69 (40%), Gaps = 10/69 (14%)

Query: 605  PLGLPPGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRPDKPLEAQLLL 664
            PL  PP    P PPPPP   P  PP       P A  Q Q P++      D PL   +++
Sbjct: 1989 PLQAPPPTPPPPPPPPPPPPPPPPPP-----PPSAPPQVQLPVS-----LDLPLFPSIMM 2038

Query: 665  NGFHHVGAP 673
                H   P
Sbjct: 2039 QPVQHPALP 2047



 Score = 35.0 bits (79), Expect = 1.0
 Identities = 23/87 (26%), Positives = 29/87 (33%), Gaps = 27/87 (31%)

Query: 1519 PVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPSSPPDPLPNEAARTAAKALL 1578
            P+      TPPPPP PP           PP   + +  GP   P+ +             
Sbjct: 1949 PISPSSPETPPPPPPPPPL---------PPAPPQPSSMGPVKIPNTVSTP---------- 1989

Query: 1579 ENFGFELVIQYNEGKQAVPPPPTPPPP 1605
                    +Q        PPPP PPPP
Sbjct: 1990 --------LQAPPPTPPPPPPPPPPPP 2008



 Score = 35.0 bits (79), Expect = 1.0
 Identities = 48/199 (24%), Positives = 71/199 (35%), Gaps = 21/199 (10%)

Query: 244  LGFSKPQ-AFMDHTQSHGVKLTPAQYQGLSGSPAVLQEGDEGCKALISFLEPKLPARPSS 302
            LG +  Q   MD +  HG+ L P  Y GL G P VL  G  G  +L  F +      P  
Sbjct: 3029 LGLTVQQPGMMDSSSLHGISL-PTAYPGLPGLPPVLLPGMNGPSSLPGFPQNSNTLTPPG 3087

Query: 303  ----DIPLDNSSTVNMEANVAQTEDGPPEAEVQALILLDEEVMALSPPSPPTATWDPSPT 358
                  P   +S+  +  + A T+           +L         PP PP+++     T
Sbjct: 3088 AGMLGFPTSATSSPALSLSSAPTKP----------LLQTPPPPPPPPPPPPSSSLSGQQT 3137

Query: 359  QAKESPVAAGEAGPDWFPEGQEEDGGLCPPLNQSSPTSKEGGTLPA---PVGSPEDPSDP 415
            + +       +  P+   + +EE+     P        K    L      VG  E   DP
Sbjct: 3138 EQQNKESEKKQTKPNKVKKIKEEELEATKPEKHPKKEEKISSALSVLGKVVG--ETHVDP 3195

Query: 416  PQPYRLADDYTPAPAAFQG 434
             Q   L +     PA+F G
Sbjct: 3196 IQLQALQNAIAGDPASFIG 3214



 Score = 34.7 bits (78), Expect = 1.3
 Identities = 21/61 (34%), Positives = 33/61 (54%), Gaps = 3/61 (4%)

Query: 238 LCLLCRLGFSKPQAFMDH-TQSHGVKLTPAQYQGLSGS--PAVLQEGDEGCKALISFLEP 294
           +C LC+L F   ++F+ H    H + L   + + LS     A++Q   +  + LISFLEP
Sbjct: 279 MCFLCKLSFGYIRSFVTHAVHDHRMTLNDEEQKLLSNKCVSAIIQGIGKDKEPLISFLEP 338

Query: 295 K 295
           K
Sbjct: 339 K 339



 Score = 34.7 bits (78), Expect = 1.3
 Identities = 24/79 (30%), Positives = 33/79 (41%), Gaps = 26/79 (32%)

Query: 2477 GQFLPFPLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNPMIPQTLIGLLPNALLQ 2536
            GQF P+        A    F  Q + AY +        L+P++P  P+T           
Sbjct: 1925 GQFFPY--------AALEKFARQYREAYDK--------LYPISPSSPET----------P 1958

Query: 2537 PPPQPPEPTATAPPKPPEL 2555
            PPP PP P   APP+P  +
Sbjct: 1959 PPPPPPPPLPPAPPQPSSM 1977



 Score = 34.7 bits (78), Expect = 1.3
 Identities = 19/51 (37%), Positives = 24/51 (47%), Gaps = 8/51 (15%)

Query: 1218 LSPLEGPNL--TPEASPDPLPEPPLASVEVPDKPSGSPGQPPSPAPSPVPE 1266
            + P++ PN   TP  +P P P PP      P  P   P  PP P PS  P+
Sbjct: 1977 MGPVKIPNTVSTPLQAPPPTPPPP------PPPPPPPPPPPPPPPPSAPPQ 2021



 Score = 34.3 bits (77), Expect = 1.7
 Identities = 33/107 (30%), Positives = 42/107 (39%), Gaps = 21/107 (19%)

Query: 2055 PGGVPSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAFPY-----PTATLAS 2109
            PG    P V  P    P+SLP F        +      P      FP      P  +L+S
Sbjct: 3054 PGLPGLPPVLLPGMNGPSSLPGFP------QNSNTLTPPGAGMLGFPTSATSSPALSLSS 3107

Query: 2110 GP-QPFLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESE 2155
             P +P L      T P P PP    PPPPPS     ++  + + ESE
Sbjct: 3108 APTKPLLQ-----TPPPPPPP----PPPPPSSSLSGQQTEQQNKESE 3145



 Score = 33.9 bits (76), Expect = 2.2
 Identities = 49/250 (19%), Positives = 90/250 (36%), Gaps = 26/250 (10%)

Query: 822  RCNICDFESNSKEKMQLHARGAAHEENSQIYKVRLGAELGLYHCLLCAWETPSRLAVLQH 881
            +C  C++ S  + ++Q+H   + H     I             C LC     +++ +  H
Sbjct: 1173 QCPYCNYNSRDQSRIQMHVL-SQHSVQPVIC------------CPLCQDVLSNKMHLQLH 1219

Query: 882  LRTPAHRDAQAQRRLQLLQNGPTTEEGLAALQSILSFSHGQLRTPAEVVPAEAG--NSQP 939
            L            +L +    P      + L    +    +  TPA V    +G  + + 
Sbjct: 1220 LTHLHSVSPDCVEKLLMTVPVPDVMMPNSMLLPAAASEKSERDTPAAVTAEGSGKYSGES 1279

Query: 940  GTIDPEGTGEEPARGCQRLHLKKKKKKKK-----EWGRASAASKGLCD---GGSHPSLTL 991
               D    G E ++    +  +++K  K+     EW + S+    + D      +     
Sbjct: 1280 PMDDKSMAGLEDSKANVEVKNEEQKPTKEPLEVSEWNKNSSKDVKIPDTLQDQLNEQQKR 1339

Query: 992  RPLPICSLQVYC--CPYCSFLSPESSQVRAHTLSQHAVQPKYRCPLCQEQLVGRPALHFH 1049
            +PL +    VY   C +CS       +++ H+   HA++    C LCQ       AL  H
Sbjct: 1340 QPLSVSDRHVYKYRCNHCSLAFKTMQKLQIHS-QYHAIRAATMCNLCQRSFRTFQALKKH 1398

Query: 1050 LSHLHNVVPE 1059
            L   H  + E
Sbjct: 1399 LEAGHPELSE 1408



 Score = 33.5 bits (75), Expect = 2.9
 Identities = 15/38 (39%), Positives = 17/38 (44%)

Query: 2521 MIPQTLIGLLPNALLQPPPQPPEPTATAPPKPPELPAP 2558
            M P  +   +   L  PPP PP P    PP PP  P P
Sbjct: 1977 MGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPPPPPPPP 2014



 Score = 32.7 bits (73), Expect = 5.0
 Identities = 14/34 (41%), Positives = 16/34 (47%)

Query: 2115 LPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPP 2148
            + P    T P P PP PL P PP     GP + P
Sbjct: 1950 ISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIP 1983



 Score = 32.3 bits (72), Expect = 6.5
 Identities = 37/147 (25%), Positives = 55/147 (37%), Gaps = 23/147 (15%)

Query: 815  SVSPLHL---RCNICDFESNSKEKMQLHARGAAHEENSQIYKVRLGAELGLYHCLLCAWE 871
            SVS  H+   RCN C     + +K+Q+H         SQ + +R         C LC   
Sbjct: 1343 SVSDRHVYKYRCNHCSLAFKTMQKLQIH---------SQYHAIRAAT-----MCNLCQRS 1388

Query: 872  TPSRLAVLQHLRTPAHRDAQAQRRLQLLQNGPTTEEGLAALQSILSFSHG-QLRTPAEVV 930
              +  A+ +HL    H +       QL  + P   E  A  +++    HG +     E  
Sbjct: 1389 FRTFQALKKHLEA-GHPELSEAELQQLYASLPVNGELWAESETMSQDDHGLEQEMEREYE 1447

Query: 931  PAEAGNSQPGTID----PEGTGEEPAR 953
                G + P   D    P+  G EP R
Sbjct: 1448 VDHEGKASPVGSDSSSIPDDMGSEPKR 1474



 Score = 32.3 bits (72), Expect = 6.5
 Identities = 23/75 (30%), Positives = 25/75 (33%), Gaps = 16/75 (21%)

Query: 2483 PLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNPMIPQTLIGLLPNALLQPPPQPP 2542
            P PP     PPA   P   G                   IP T+   L      PPP PP
Sbjct: 1959 PPPPPPPPLPPAPPQPSSMGPV----------------KIPNTVSTPLQAPPPTPPPPPP 2002

Query: 2543 EPTATAPPKPPELPA 2557
             P    PP PP  P+
Sbjct: 2003 PPPPPPPPPPPPPPS 2017



 Score = 32.0 bits (71), Expect = 8.5
 Identities = 30/138 (21%), Positives = 52/138 (37%), Gaps = 21/138 (15%)

Query: 1803 ASGCRRCHATFSCVFELVRHLKKCYDDQTLEEEEE-------------------EAERGE 1843
            A+ C  C  +F     L +HL+  + + +  E ++                   + + G 
Sbjct: 1379 ATMCNLCQRSFRTFQALKKHLEAGHPELSEAELQQLYASLPVNGELWAESETMSQDDHGL 1438

Query: 1844 EEEEVEEEEVEEEQGLEPPAGPEGPLPEPPDGEELSQAEATKAGGKEPEEKATPSPSPAH 1903
            E+E   E EV+ E    P       +P+   G E  +    + G     EK    PS  +
Sbjct: 1439 EQEMEREYEVDHEGKASPVGSDSSSIPDDM-GSEPKRTLPFRKGPNFTMEKFL-DPSRPY 1496

Query: 1904 TCDQCAISFSSQDLLTSH 1921
             C  C  SF+ +++L  H
Sbjct: 1497 KCTVCKESFTQKNILLVH 1514


>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
          Length = 1003

 Score = 78.2 bits (191), Expect = 1e-13
 Identities = 78/261 (29%), Positives = 103/261 (39%), Gaps = 25/261 (9%)

Query: 2313 RAQLKSESKCYDLAPA---PEAPPALKAPPATTPASMPLGAAPTLPRLAPVLLSGPALAQ 2369
            RAQ  S S    L P+   P  PP +           P  + P  P   P   S P  +Q
Sbjct: 347  RAQAPSASHSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQ 406

Query: 2370 PPLGNLAPF----NSGPAASSGLLGLATSV--LPTTTVVQTAGPGRPLPQRPMPDQTNTS 2423
            P L ++         GP+ S G   L  S   LP    + +  P  P P+ P+      +
Sbjct: 407  PILPSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSP--PQPRHPIQPSLPGT 464

Query: 2424 TAGTTDPVPGPPTEPLGDKVSSERKPVAGPTSSSNDALKNLKALKTTVPALLGGQFLPFP 2483
            T+G+   VPG P  P   K      PV     S ++ L         +P L GG+  PFP
Sbjct: 465  TSGSLSSVPGAPAPPAASKAPVVPSPVL---QSPSEGLGMGAGPACPLPPLAGGEAFPFP 521

Query: 2484 LPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNPMIPQTLIGLLPNALLQPPPQP-- 2541
             P  G     A F P + GA    L     G  P +P++  +L G+L     QPPP+P  
Sbjct: 522  SPEQGLALSGAGF-PGMLGALPLPL---SLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLL 577

Query: 2542 PEPTATAPPKPPELPAPGEGE 2562
            P P    PP      APGE E
Sbjct: 578  PPPGGPGPPL-----APGEPE 593



 Score = 48.1 bits (113), Expect = 1e-04
 Identities = 87/337 (25%), Positives = 117/337 (34%), Gaps = 58/337 (17%)

Query: 2065 PPATATPASLPKFN-LLLGKVDDGTGREAPKREAPAFPYPTATLASGPQPFLPPGKEATT 2123
            P +   P   P  N  L G +  G G+  P+   P  P P      GP P L PG+    
Sbjct: 544  PLSLGQPPPSPLLNHSLFGVLTGGGGQPPPE---PLLPPP-----GGPGPPLAPGE---- 591

Query: 2124 PTPEPPLPL---LPPPPPSEEEGPEEPPKASPESEACSLSAGDLSDSSASSLAEPESPGA 2180
              PE P  L   L PPPPS+      PP ++P S   +     L+    +   E  + GA
Sbjct: 592  --PEGPSLLVASLLPPPPSDLL----PPPSAPPSNLLASFLPLLALGPTAGDGEGSAEGA 645

Query: 2181 GGTSGGPGGGTG--VPDGMGQRRYRTQMSSLQLKIMKACYEAYRTPTMQECEVLGEEIGL 2238
            GG SG P  G G   P           + +L   ++ A  +       Q C +   + G 
Sbjct: 646  GGPSGEPFSGLGDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAPQPGP 705

Query: 2239 PKRVIQVWFQNARAKEKKAKLQGTAAGSTGGSSEGLLAAQRTDCPYCDVKYDFYVSCRGH 2298
            P   +                  TA    G SS G  A   +  P   +      S  G 
Sbjct: 706  PTSSVT-----------------TATTDPGASSLG-KAPSNSGRPPQLLSPLLGASLLGD 747

Query: 2299 LFSRQHLAKLKEAVRAQLKSESKCYDLAPAPEAPPALKAPPATTPASMPLGA-------- 2350
            L S   L     A+ + L+            +  P   APP  + AS PL          
Sbjct: 748  LSS---LTSSPGALPSLLQPPGPLLSGQLGLQLLPGGGAPPPLSEASSPLACLLQSLQIP 804

Query: 2351 -----APTLPRLAPVLLSGPALAQPPLGNLAPFNSGP 2382
                 AP LP  +P     P  A+PPL  LAP +  P
Sbjct: 805  PEQPEAPCLPPESPASALEPEPARPPLSALAPPHGSP 841



 Score = 44.7 bits (104), Expect = 0.001
 Identities = 114/462 (24%), Positives = 151/462 (32%), Gaps = 106/462 (22%)

Query: 9   TTGTTPSPGHN-APSLPSDTFSSSTPSDPVTKDPPAASSTSENMRSSEPGGQLLESGCGL 67
           ++G+ P P H   PSLP  T S S  S P    PPAAS                     +
Sbjct: 446 SSGSPPQPRHPIQPSLPGTT-SGSLSSVPGAPAPPAASKAP------------------V 486

Query: 68  VPPKEIGEPQEGPDCGHFPPNDPGVEKDKEQEEEEEGLPPMDLSNHLFFTAGGEAYLVAK 127
           VP   +  P EG   G  P                  LPP+         AGGEA+    
Sbjct: 487 VPSPVLQSPSEGLGMGAGPACP---------------LPPL---------AGGEAF---P 519

Query: 128 LSLPGGSELLLPKGFPWGEAGIKEEPSLPF-LAYPPPSHLTALHIQHGFDPIQGFSSSDQ 186
              P     L   GFP    G+     LP  L  PPPS L   H   G     G     +
Sbjct: 520 FPSPEQGLALSGAGFP----GMLGALPLPLSLGQPPPSPLLN-HSLFGVLTGGGGQPPPE 574

Query: 187 ILSHDTSAPSP--AACEERHGAFWSYQLAPNPPGD---PKDGPMGNSGGNHVAVFWLCLL 241
            L      P P  A  E    +     L P PP D   P   P  N     +   +L LL
Sbjct: 575 PLLPPPGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAPPSN-----LLASFLPLL 629

Query: 242 CRLGFSKPQAFMDHTQSHGV------------KLTPAQYQGLSGSPAVLQ---------- 279
             LG   P A      + G              L+P  +  LS  P ++           
Sbjct: 630 A-LG---PTAGDGEGSAEGAGGPSGEPFSGLGDLSPLLFPPLSAPPTLIALNSALLAATL 685

Query: 280 EGDEGCKALISFLEPKLPARPSSDIPLDNSSTVNMEANVAQTEDGPPEAEVQAL----IL 335
           +   G       L    P  P+S +    +         A +  G P   +  L    +L
Sbjct: 686 DPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLL 745

Query: 336 LDEEVMALSPPSPPTATWDPSPTQAKESPVAAGEAGPDWFPEGQEEDGGLCPPLNQ-SSP 394
            D   +  SP + P+    P        P+ +G+ G    P      GG  PPL++ SSP
Sbjct: 746 GDLSSLTSSPGALPSLLQPP-------GPLLSGQLGLQLLP-----GGGAPPPLSEASSP 793

Query: 395 TSKEGGTLPAPVGSPEDPSDPPQPYRLADDYTPAPAAFQGLS 436
            +    +L  P   PE P  PP+    A +  PA      L+
Sbjct: 794 LACLLQSLQIPPEQPEAPCLPPESPASALEPEPARPPLSALA 835



 Score = 42.4 bits (98), Expect = 0.006
 Identities = 131/641 (20%), Positives = 192/641 (29%), Gaps = 122/641 (19%)

Query: 2059 PSPAVKPPATATPASLPKFNLLLGKVDDGTGREAP------------KREAPAFPYPTAT 2106
            P PA +PP ++    LP     LG      G  AP            K + P  P P+  
Sbjct: 282  PGPASQPPVSSATMHLPLVLGPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTL 341

Query: 2107 LASGPQPFLPPGKEATTPTPEPPLPLLPPP--PPSEEEGPEEPPKASPESEACSLSAGDL 2164
                P+   P    +++  P    P  PP      E  GP+ P ++ P + A       L
Sbjct: 342  QGRRPRAQAPSASHSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSL 401

Query: 2165 SDSSASSLAEPESPGAGGTSGGPGGGTGVPDGMGQRRYRTQMSSLQLKIMKACYEAYRTP 2224
             + S     +P  P      G P  G    DG                            
Sbjct: 402  PEPS-----QPILPSVLSLLGLPTPGPSHSDG---------------------------- 428

Query: 2225 TMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAKLQGTAAGSTGGSSEGLLAAQRTDCPY 2284
                  +LG +  LP         +    + +  +Q +  G+T GS   L +      P 
Sbjct: 429  ---SFNLLGSDAHLPP---PPTLSSGSPPQPRHPIQPSLPGTTSGS---LSSVPGAPAPP 479

Query: 2285 CDVKYDFYVSCRGHLFSRQHLAKLKEAVRAQLKSESKCYDLAPAPEAPPAL--KAPPATT 2342
               K                 A +  +   Q  SE       PA   PP    +A P  +
Sbjct: 480  AASK-----------------APVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPS 522

Query: 2343 PASMPLGAAPTLPRLAPVLLSGPALAQPPLGNLAPFNSGPAASSGLLGLAT----SVLPT 2398
            P      +    P +   L    +L QPP          P  +  L G+ T       P 
Sbjct: 523  PEQGLALSGAGFPGMLGALPLPLSLGQPP--------PSPLLNHSLFGVLTGGGGQPPPE 574

Query: 2399 TTVVQTAGPGRPLPQRPMPDQTNTSTAGTTDPVPG----PPTEPLGDKVSSERKPVA-GP 2453
              +    GPG PL     P+  +   A    P P     PP+ P  + ++S    +A GP
Sbjct: 575  PLLPPPGGPGPPLAPGE-PEGPSLLVASLLPPPPSDLLPPPSAPPSNLLASFLPLLALGP 633

Query: 2454 TSSSNDALKNLKALKTTVPALLGGQFLPFPLPPAGGTAPPAVFGPQLQGAYFQQLYGMKK 2513
            T+   +         +  P    G   P   PP   +APP +    L  A          
Sbjct: 634  TAGDGEGSAEGAGGPSGEPFSGLGDLSPLLFPPL--SAPPTLIA--LNSALLAATLDPPS 689

Query: 2514 GLFPMNPMIPQTLIGLLPNALLQPPPQPPEPTATAPPKPPELPAPGE--GEAGEVDELLT 2571
            G  P             P  L  P P PP  + T     P   + G+    +G   +LL+
Sbjct: 690  GTPPQ------------PCVLSAPQPGPPTSSVTTATTDPGASSLGKAPSNSGRPPQLLS 737

Query: 2572 GSTGISTVDVTHRYLCRQCKMAFDGEAPATAHQRSFCFFGRGS-----GGSMPPPLRVPI 2626
               G S +             +  G  P+          G+       GG  PPPL    
Sbjct: 738  PLLGASLLGDL------SSLTSSPGALPSLLQPPGPLLSGQLGLQLLPGGGAPPPLSEAS 791

Query: 2627 CTYHCLACEVLLSGREALASHLRSSAHRRKAAPPQGGPPIS 2667
                CL   + +   +  A  L   +      P    PP+S
Sbjct: 792  SPLACLLQSLQIPPEQPEAPCLPPESPASALEPEPARPPLS 832



 Score = 40.4 bits (93), Expect = 0.024
 Identities = 82/313 (26%), Positives = 100/313 (31%), Gaps = 101/313 (32%)

Query: 2330 EAPPALKAPPATTPASMPLGAAPTLPRLAPVLLSGP-----ALAQPPLGNLAPFNSGPAA 2384
            + PP    PP   P           P LAP    GP     +L  PP  +L P  S P +
Sbjct: 570  QPPPEPLLPPPGGPG----------PPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAPPS 619

Query: 2385 SSGLLGLATSVLPTTTVVQTAGPGR--------------------------PLPQRPMPD 2418
            +     L  S LP   +  TAG G                           PL   P   
Sbjct: 620  N-----LLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFSGLGDLSPLLFPPLSAPPTLI 674

Query: 2419 QTNTS-TAGTTD--------------PVPGPPT------------EPLGDKVSSERKP-- 2449
              N++  A T D              P PGPPT              LG   S+  +P  
Sbjct: 675  ALNSALLAATLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGASSLGKAPSNSGRPPQ 734

Query: 2450 ---------VAGPTSSSNDALKNLKALKTTVPALLGGQFLPFPLPPAGGTAPPAVFGPQL 2500
                     + G  SS   +   L +L      LL GQ L   L P GG  PP       
Sbjct: 735  LLSPLLGASLLGDLSSLTSSPGALPSLLQPPGPLLSGQ-LGLQLLPGGGAPPPLSEASSP 793

Query: 2501 QGAYFQQLYGMKKGLFPMNPMIPQTLIGLLPNALLQPPPQPPEPTATAPPK-PPELPAPG 2559
                 Q L      + P  P  P  L    P + L+P P  P  +A APP   P+ P P 
Sbjct: 794  LACLLQSLQ-----IPPEQPEAP-CLPPESPASALEPEPARPPLSALAPPHGSPDPPVP- 846

Query: 2560 EGEAGEVDELLTG 2572
                    ELLTG
Sbjct: 847  --------ELLTG 851



 Score = 37.7 bits (86), Expect = 0.15
 Identities = 48/169 (28%), Positives = 58/169 (34%), Gaps = 23/169 (13%)

Query: 1444 GPDTSGFISGLPFLSPPPPPLDLHRFPAPLFTPPVLPPFPLVPESLLKLQQQQLLLPFYL 1503
            GP TS   +     +  P    L + P+    PP L   PL+  SLL         P  L
Sbjct: 704  GPPTSSVTTA----TTDPGASSLGKAPSNSGRPPQLLS-PLLGASLLGDLSSLTSSPGAL 758

Query: 1504 HDLKVGPKLTLAGPAPVLSLPAATPPPPPQPPKAELA--EREWERPPMAKEGNEAGPSSP 1561
              L   P   L+G   +  LP    PPP     + LA   +  + PP   E     P SP
Sbjct: 759  PSLLQPPGPLLSGQLGLQLLPGGGAPPPLSEASSPLACLLQSLQIPPEQPEAPCLPPESP 818

Query: 1562 PDPLPNEAARTAAKALLENFGFELVIQYNEGKQAVPPPPTPPPPEALGG 1610
               L  E AR    AL    G                 P PP PE L G
Sbjct: 819  ASALEPEPARPPLSALAPPHG----------------SPDPPVPELLTG 851



 Score = 37.0 bits (84), Expect = 0.26
 Identities = 97/378 (25%), Positives = 127/378 (33%), Gaps = 71/378 (18%)

Query: 1861 PPAGP--EGPLPEPPDGEELSQAEATKAG--GKEPEEKATPSPSPAHTCDQCAISFSSQD 1916
            PP  P   GP   PP+   +SQA  T AG  G  P   A P PS            SS  
Sbjct: 152  PPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLADPVPSGGS---------SSPR 202

Query: 1917 LLTSHRRLHFLPSLQPSAPPQL-LDLPLLVFGE--RNPLV-----------AATSPMPGP 1962
             L         PS  P  PP + L+ P   +G   R+ LV           A++SP   P
Sbjct: 203  FLPRGNA----PSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPSDP 258

Query: 1963 PLKRKHEDGSLSP------TGSEAGGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNP 2016
            PL   H   +L+P          A  G   +PP      T  LP  L  L      +   
Sbjct: 259  PLF--HCSDALTPPPLPPSNNLPAHPGPASQPPVSSA--TMHLPLVLGPLGGAPTVEGPG 314

Query: 2017 TRKMLDCISEEVGLKKRVVQVWFQNT-RARERKGQFRSTPGGVPSPAVKPPATATPASLP 2075
                L         K +   +   +T + R  + Q    P    S +++P          
Sbjct: 315  APPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQ---APSASHSSSLRPSQRRPRRPPT 371

Query: 2076 KFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQPFLPPGKEATT----PTPEPPL- 2130
             F LL     +G G + P+R  P  P P     S P+P  P      +    PTP P   
Sbjct: 372  VFRLL-----EGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSHS 426

Query: 2131 ----------PLLPPPP------PSEEEGPEEPPKASPESEACSLSAGDLSDSSASSLAE 2174
                        LPPPP      P +   P +P      S + S   G  +  +AS    
Sbjct: 427  DGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPV 486

Query: 2175 PESPGAGGTSGGPGGGTG 2192
              SP     S G G G G
Sbjct: 487  VPSPVLQSPSEGLGMGAG 504



 Score = 35.4 bits (80), Expect = 0.77
 Identities = 34/137 (24%), Positives = 50/137 (36%), Gaps = 13/137 (9%)

Query: 2053 STPGGVPSPAV------KPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAFPYPTAT 2106
            S+PG   SP +       PP+   P  +P    L G    G G   P+  + +  +PT  
Sbjct: 124  SSPGEGASPQMFHTVSPGPPSARPPCRVPPTTPLNG----GPGSLPPEPPSVSQAFPTL- 178

Query: 2107 LASGPQPFLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESEACSLSAGDLSD 2166
              +GP    PP      P+     P   P   +    P  PP  S  + + +  A   S 
Sbjct: 179  --AGPGGLFPPRLADPVPSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSS 236

Query: 2167 SSASSLAEPESPGAGGT 2183
               S L  P +P A  +
Sbjct: 237  LVPSDLGSPPAPHASSS 253



 Score = 34.7 bits (78), Expect = 1.3
 Identities = 38/125 (30%), Positives = 43/125 (34%), Gaps = 30/125 (24%)

Query: 604 LPLGLPPGLMGPGPPPPPGATPTSP-----PELFQYFGPQALGQPQTPLAGPGLRPDKPL 658
           LP G  P    P PPPPP  +  +P       L     P  LG P  P A      D PL
Sbjct: 204 LPRGNAPS---PAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPSDPPL 260

Query: 659 EAQLLLNGFHHVGA------------PARKFPTSAPGSLSPDAHLP--PSQLLGSSSDSL 704
                   FH   A            PA   P S P   S   HLP     L G+ +   
Sbjct: 261 --------FHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGPLGGAPTVEG 312

Query: 705 PTSPP 709
           P +PP
Sbjct: 313 PGAPP 317



 Score = 33.9 bits (76), Expect = 2.2
 Identities = 44/157 (28%), Positives = 52/157 (33%), Gaps = 21/157 (13%)

Query: 1458 SPPPPPLDLHRFPAPLFTPPVLPPFPLVPE-----SLLKLQQQQLLLPFYLHDLKVGPKL 1512
            SPP  P   H   A   TPP LPP   +P      S   +    + LP  L  L   P +
Sbjct: 253  SPPSDPPLFHCSDA--LTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGPLGGAPTV 310

Query: 1513 TLAGPAP-----VLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPSSPPDPLPN 1567
               G  P     +LS  A    PP  PP      R   + P A   +   PS      P 
Sbjct: 311  EGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSSLRPSQRRPRRPP 370

Query: 1568 EAARTAAKALLENFGFELVIQYNEGKQAVPPPPTPPP 1604
               R     LLE  G     Q     +   P P P P
Sbjct: 371  TVFR-----LLEGRG----PQTPRRSRPRAPAPVPQP 398



 Score = 33.9 bits (76), Expect = 2.2
 Identities = 32/100 (32%), Positives = 41/100 (41%), Gaps = 22/100 (22%)

Query: 612 LMGPGPPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRPDKPLEAQLLLNGFHHVG 671
           L G GP  P  + P +P  + Q   P +L +P  P+          L + L L G    G
Sbjct: 376 LEGRGPQTPRRSRPRAPAPVPQ---PFSLPEPSQPI----------LPSVLSLLGLPTPG 422

Query: 672 APARKFPTSAPGS---LSPDAHLPPSQLLGSSSDSLPTSP 708
                 P+ + GS   L  DAHLPP   L S S   P  P
Sbjct: 423 ------PSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHP 456



 Score = 33.5 bits (75), Expect = 2.9
 Identities = 30/108 (27%), Positives = 43/108 (39%), Gaps = 24/108 (22%)

Query: 345 PPSPPTATWD-PS--------PTQAKESPVAAGEAGPDWFPEGQEEDGGLCPP----LN- 390
           PP PP+ +   P+        P +  +   + G + P + P G        PP    LN 
Sbjct: 165 PPEPPSVSQAFPTLAGPGGLFPPRLADPVPSGGSSSPRFLPRGNAPSPAPPPPPAISLNA 224

Query: 391 ---------QSSPTSKEGGTLPAPVGSPEDPSDPPQPYRLADDYTPAP 429
                    +SS    + G+ PAP  S   PSDPP  +  +D  TP P
Sbjct: 225 PSYNWGAALRSSLVPSDLGSPPAPHASSSPPSDPPL-FHCSDALTPPP 271



 Score = 33.1 bits (74), Expect = 3.8
 Identities = 29/76 (38%), Positives = 39/76 (51%), Gaps = 8/76 (10%)

Query: 1198 LGIEWVGSG-----LNEVPSSLYFLLSPLEGPNLTPEASPDPLPEPPLASVEV-PDKPSG 1251
            LG++ +  G     L+E  S L  LL  L+ P   PEA   P PE P +++E  P +P  
Sbjct: 773  LGLQLLPGGGAPPPLSEASSPLACLLQSLQIPPEQPEAPCLP-PESPASALEPEPARPPL 831

Query: 1252 SPGQPPSPAPS-PVPE 1266
            S   PP  +P  PVPE
Sbjct: 832  SALAPPHGSPDPPVPE 847



 Score = 32.3 bits (72), Expect = 6.5
 Identities = 82/298 (27%), Positives = 98/298 (32%), Gaps = 60/298 (20%)

Query: 2332 PPALKAP---PATTPASMPLGAAPTLPRLAPVLLSGPALAQPPLGNLAPFNSGPAASSGL 2388
            PP+ + P   P TTP +   G+ P  P    V  + P LA P  G   P  + P  S G 
Sbjct: 142  PPSARPPCRVPPTTPLNGGPGSLP--PEPPSVSQAFPTLAGPG-GLFPPRLADPVPSGG- 197

Query: 2389 LGLATSVLPTTTVVQTAGPGRPLPQRPMPDQTNTSTAGTTDPVPGPPTEPLGDKVSSERK 2448
               +   LP       A P  P      P   N   A  +  VP     P     SS   
Sbjct: 198  -SSSPRFLPRGNAPSPAPPPPPAISLNAPSY-NWGAALRSSLVPSDLGSPPAPHASSS-P 254

Query: 2449 PVAGPTSSSNDAL--------KNLKA---LKTTVPALLGGQFLPFPLPPAGGTAPPAVFG 2497
            P   P    +DAL         NL A     +  P       LP  L P GG   P V G
Sbjct: 255  PSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGPLGGA--PTVEG 312

Query: 2498 PQLQGAYFQQLY-GMKKGLFPMNPMIPQTLIGLLPNA---------LLQP----PPQPP- 2542
            P         L     K   P  P  P TL G  P A          L+P    P +PP 
Sbjct: 313  PGAPPFLASSLLSAAAKAQHPPLPP-PSTLQGRRPRAQAPSASHSSSLRPSQRRPRRPPT 371

Query: 2543 ----------------EPTATAP-PKPPELPAPGEGEAGEVDELLTGSTGISTVDVTH 2583
                             P A AP P+P  LP P +     V  LL    G+ T   +H
Sbjct: 372  VFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLL----GLPTPGPSH 425



 Score = 32.0 bits (71), Expect = 8.5
 Identities = 44/164 (26%), Positives = 58/164 (35%), Gaps = 25/164 (15%)

Query: 2404 TAGPGRPLPQRPMPDQTNTSTAGTTDPVPGPPTEPLGDKVSSERKPVAGPTSSSNDALKN 2463
            T  PG P  + P      T   G    +P  P       VS     +AGP       L +
Sbjct: 137  TVSPGPPSARPPCRVPPTTPLNGGPGSLPPEPPS-----VSQAFPTLAGPGGLFPPRLAD 191

Query: 2464 -LKALKTTVPALLGGQFLPFPLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNPMI 2522
             + +  ++ P  L     P P PP     PPA+    L    +     ++  L P +   
Sbjct: 192  PVPSGGSSSPRFLPRGNAPSPAPPP----PPAI---SLNAPSYNWGAALRSSLVPSDLGS 244

Query: 2523 PQTLIGLLPNALLQPPPQPP----EPTATAPPKPP--ELPA-PG 2559
            P       P+A   PP  PP        T PP PP   LPA PG
Sbjct: 245  PPA-----PHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPG 283



 Score = 32.0 bits (71), Expect = 8.5
 Identities = 35/111 (31%), Positives = 43/111 (38%), Gaps = 13/111 (11%)

Query: 2053 STPGGVPSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQ 2112
            S+PG +PS  ++PP       L    LL      G G   P  EA +   P A L    Q
Sbjct: 753  SSPGALPS-LLQPPGPLLSGQLG-LQLL-----PGGGAPPPLSEASS---PLACLLQSLQ 802

Query: 2113 PFLPPGK-EATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESEACSLSAG 2162
              +PP + EA    PE P   L P P         PP  SP+     L  G
Sbjct: 803  --IPPEQPEAPCLPPESPASALEPEPARPPLSALAPPHGSPDPPVPELLTG 851


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 75.5 bits (184), Expect = 7e-13
 Identities = 210/816 (25%), Positives = 281/816 (34%), Gaps = 156/816 (19%)

Query: 1422 PERSQEEPKEGETEGEVGTEKKGPDTSGFISGLPFLSPPPPPLDLHRFPAPLFTP-PVLP 1480
            PE S + P  G  +  +G  +  P   G     P  S    P   +R P+P  T  P   
Sbjct: 870  PEESLDPP--GAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFV 927

Query: 1481 PFPLV--PESLLKLQQQQLLLPFY-LHDLKVGPKLTLAGPAPVLSLPAATPPPPPQPPKA 1537
            P   +  P+SLL+ +++        +           AGP      P A   PPP PP  
Sbjct: 928  PLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPPGPPAY 987

Query: 1538 ELAEREWERPPMAKEGNEAGPSSPPDPL-PNEAARTAAKALLENFGFELVIQYNEGKQAV 1596
            +        P      + AGP +P   L PN+     +    E  G   +IQ    + A 
Sbjct: 988  DPYG-----PYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLG---LIQSGPHQAAP 1039

Query: 1597 PPPPTPPPPEALGGGDKLACGACGKLFSNML---ILKTHEEHV-HRRFLPFEALSRYAAQ 1652
            PPPP PPPP A     K   G    +F +     +LKT   H+  RR  PF+   +  AQ
Sbjct: 1040 PPPPPPPPPPAPASEPK--GGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPKKLYAQ 1097

Query: 1653 ---FRKSYDSLYPPL---AEPPKPPD-GSLDSPVPHLGP----PFLVPEPEAGGTRAPEE 1701
               F    D    P      P + PD  S     P L P     F  P P   G   P  
Sbjct: 1098 EYEFEADEDKADVPADIRLNPRRLPDLVSSCRSRPALSPLGDIDFCPPNP---GPDGPRR 1154

Query: 1702 RSRAGGHWPIEEEESSRGNLPPLVPAGRRFSRTKFTEFQTQALQSFFETSAYPKDGEVER 1761
            R R        +   ++ + PP  P GR   R +  E  T A  +   T   P DG  + 
Sbjct: 1155 RGR--------KPTKAKRDGPPR-PRGR--PRIRPLEVPTTAGPASAST---PTDGAKKP 1200

Query: 1762 LASLLGLASRVVVVWFQNARQKARKNACEGGSMPTGG-GTGGASGCRRCHATFSCVFELV 1820
                 G   +         R +  K      S+P  G G G +SG        + +    
Sbjct: 1201 RGRGRGRGRKAEEAG--GTRLEPLKPLKIKLSVPKAGEGLGTSSGDAISGTDHNSL---- 1254

Query: 1821 RHLKKCYDDQTLEEEEEEAERGEEEEEVEEEEVEEEQGLEPPAGPEGPLPEPPDGEELSQ 1880
                    D +L  E+ EA+          +EVEE+Q            PE   G   S 
Sbjct: 1255 --------DSSLTREKIEAKI---------KEVEEKQ------------PEMKSGFMASF 1285

Query: 1881 AEATKAGGKEP---EEKATPSPSPAHTCDQCAISFSSQDLLTSHRRLHFLPSLQPSAPPQ 1937
             +  K+G + P   +   TP  SP                           S+ PS P +
Sbjct: 1286 LDFLKSGKRHPPLYQAGLTPPLSPPK-------------------------SVPPSVPAR 1320

Query: 1938 LLDLPLLVFGERNPLVAATSPMPGPPLKRKHEDGSLSPTGSEAGGGGEGEPPRDKRLRTT 1997
             L           P   AT  +P PP       G  +   +E+ G G G P   KRL   
Sbjct: 1321 GLQ----------PQPPATPAVPHPPPSGAFGLGG-ALEAAESEGLGLGCPSPCKRLDEE 1369

Query: 1998 ILPEQLEILYRWYMQDSNPTRKMLDC---ISEEVGLKKRVVQVWFQNTRARERKGQFRST 2054
             L   LE L  +   + +   K  D    IS  +           ++T          ST
Sbjct: 1370 -LKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDT----------ST 1418

Query: 2055 PGGVP-SPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGP-- 2111
            P G P +PA   P       LP  N   G  +     E P    P  P P       P  
Sbjct: 1419 PDGPPLAPAAAVPGPPPLPGLPSANSN-GTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPP 1477

Query: 2112 -QPFLP--PGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPK-----ASPESEACSLSAGD 2163
             QP LP  P   A TP+  PP PL PPPPP+    P  PP      A+P  E  + S  D
Sbjct: 1478 PQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPED 1537

Query: 2164 --LSDSSASSLAEPESPGA--GGT--SGGPGGGTGV 2193
              L D+    LA+ +   A  G T    G  GG G+
Sbjct: 1538 PELPDTRPLHLAKKQETAAVCGETDEEAGESGGEGI 1573



 Score = 44.7 bits (104), Expect = 0.001
 Identities = 166/778 (21%), Positives = 238/778 (30%), Gaps = 194/778 (24%)

Query: 1883 ATKAGGKEPEEKATPSPSPAHTCDQCAISFSSQDLLTSHRRLHFLPSLQPSA---PPQLL 1939
            AT+ G  +P     P P P                L +H R H L    PS    P + L
Sbjct: 827  ATRDGAPQPPPPPPPPPPPMPL------------QLEAHLRSHGLEPAAPSPRLRPEESL 874

Query: 1940 DLPLLVFGERNPLVAATSPMP--------GPPLKRKHEDGSLSPTGSEAGGGGEG-EPPR 1990
            D P    G    L+ A  P+P        GPP    + +G   P G+      +G + PR
Sbjct: 875  DPP----GAMQELLGALEPLPPAPGDTGVGPP----NSEGK-DPAGAYRSPSPQGTKAPR 925

Query: 1991 DKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQNTRARERKGQ 2050
               L +   P+ L       +QD    R     + E  G         +      E +G 
Sbjct: 926  FVPLTSICFPDSL-------LQDEE--RSFFPTMEEMFG---GGAADDYGKAGPPEDEGD 973

Query: 2051 FRSTPGGVPSPAVKPPATATPASLPKFNLLLGKVDDGTGREAP-----KREAPAFPY--- 2102
             ++  G  P P         PA  P      G+   G G E P       + P  P    
Sbjct: 974  PKAGAGPPPGP---------PAYDPYGPYCPGRAS-GAGPETPGLGLDPNKPPELPSTVN 1023

Query: 2103 --PTATLASGPQPFLPPGKEATTPTPEPPLPLLPPP------------------------ 2136
              P   + SGP    PP      P P PP P   P                         
Sbjct: 1024 AEPLGLIQSGPHQAAPP---PPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHL 1080

Query: 2137 -----PP---------------SEEEGPEEP------PKASPESEACSLSAGDLSDSSAS 2170
                 PP               ++E+  + P      P+  P+  +   S   LS     
Sbjct: 1081 LRRRDPPFQTPKKLYAQEYEFEADEDKADVPADIRLNPRRLPDLVSSCRSRPALSPLGDI 1140

Query: 2171 SLAEPESPGAGGTSGGPGGGTGVPDGMGQRRYRTQMSSLQLKIMKACYEAYRTPTMQECE 2230
                P     G    G        DG  + R R ++  L++        A  TPT    +
Sbjct: 1141 DFCPPNPGPDGPRRRGRKPTKAKRDGPPRPRGRPRIRPLEVPTTAGPASA-STPTDGAKK 1199

Query: 2231 VLGEEIGLPKRVIQVWFQNARA-KEKKAKLQGTAAGSTGGSSEGLLAAQRTDCPYCDVKY 2289
              G   G  ++  +         K  K KL    AG   G+S G  A   TD        
Sbjct: 1200 PRGRGRGRGRKAEEAGGTRLEPLKPLKIKLSVPKAGEGLGTSSGD-AISGTD-------- 1250

Query: 2290 DFYVSCRGHLFSRQHLAKLKEAVRAQLKSES----KCYDLAPAPEAPPALKAPPATTPAS 2345
              + S    L   +  AK+KE    Q + +S       D   + +  P L     T P S
Sbjct: 1251 --HNSLDSSLTREKIEAKIKEVEEKQPEMKSGFMASFLDFLKSGKRHPPLYQAGLTPPLS 1308

Query: 2346 MPLGAAPTLPR--LAPVLLSGPALAQPPLGNLAPFNSGPAASSGLLGLATSVLPTTTVVQ 2403
             P    P++P   L P   + PA+  PP          P+ + GL G   +       + 
Sbjct: 1309 PPKSVPPSVPARGLQPQPPATPAVPHPP----------PSGAFGLGGALEAAESEGLGLG 1358

Query: 2404 TAGPGRPLPQRPMPDQTNTSTAGTTDPVPGPPTEPLGDKVSS-----ERKPVAGPTSSSN 2458
               P + L +    +     +  + +         L + +SS     +  P+AGP  +S 
Sbjct: 1359 CPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTST 1418

Query: 2459 D------------------ALKNLKALKTTVPALLGGQFLPFPLPPAGGTAPPAVFGPQL 2500
                                L +  +  T  P LL  +  P P PP   T  P    P  
Sbjct: 1419 PDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEK--PPPTPPPAPTPQPQPPPPPP 1476

Query: 2501 QGAYFQQLYGMKKGLFPMNPMIPQTLIGLLPNALLQPPPQPPEPTATAPPKPPELPAP 2558
                            P  P +P       P  L+ P P  P P    PP PP +P+P
Sbjct: 1477 ----------------PPQPALPS------PPPLVAPTPSSPPPPPLPPPPPPAMPSP 1512



 Score = 44.3 bits (103), Expect = 0.002
 Identities = 28/87 (32%), Positives = 33/87 (37%), Gaps = 2/87 (2%)

Query: 1220 PLEGPNLTPEASPDPLPEPPLASVEVPDKPSGSPGQPPSPAPSPVPEPDAQAEDVAPPPT 1279
            P   P  TP+  P P P PP  ++  P  P      P SP P P+P P   A    PPP 
Sbjct: 1459 PTPPPAPTPQPQPPPPPPPPQPAL--PSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPP 1516

Query: 1280 MAEEEEGTTGELRSAEPAPADSRHPLT 1306
                          A P+P D   P T
Sbjct: 1517 PPAAAPLAAPPEEPAAPSPEDPELPDT 1543



 Score = 41.2 bits (95), Expect = 0.014
 Identities = 50/173 (28%), Positives = 62/173 (35%), Gaps = 41/173 (23%)

Query: 1469 FPAP----LFTPPVLPPFP--LVPESLLKLQQQQL-LLPFYL--HDLKVGPKLTLAGPAP 1519
            FP P    L  PP  PP    L P  +L L+  Q   +P  L    L  G  L  AG  P
Sbjct: 162  FPVPSSLSLQDPPFSPPANGLLSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPAGLGP 221

Query: 1520 VLSLPAATPPPPPQPPKAEL--------------AEREWERPPMAK-EGNEAGPSSPPDP 1564
              + P    PP P PP   L              A  E   P +    G   GP  P   
Sbjct: 222  AQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPERA 281

Query: 1565 LPNEAARTAAKALLENFGFELVIQYNEGKQAVPPPPTPPPPEALGGGDKLACG 1617
            LP +               + VI++ +   +  PPP PPP  AL     L+CG
Sbjct: 282  LPRQ---------------DTVIKHYQRPASAQPPPPPPPAHAL--QHYLSCG 317



 Score = 40.8 bits (94), Expect = 0.018
 Identities = 97/389 (24%), Positives = 127/389 (32%), Gaps = 73/389 (18%)

Query: 1366 GEAGAPPTTT--AATDKPFKCTVCRVSYNQSSTLEIHMRSVLHQTRSRGTKTDSKIEGPE 1423
            G AG PP T    A + P +  +  V    S++L+    + L     R      K +GPE
Sbjct: 678  GGAGGPPGTPYELAKEDPQRYHLQSV-IRTSASLDEGATAALELGLGR---LKEKKKGPE 733

Query: 1424 RSQEEPKEGETEGEVGTEKKGPDTSGFISGLPFLSPPPPPLDLHRFPAP--LFTPPVLPP 1481
            R  E P EG     V       +   F+   P   PPPPP      P P  L      P 
Sbjct: 734  RGGETP-EGLATSVVHYGAGAKELGAFLQKSP---PPPPPTAQSTQPTPHGLLLEAGGPD 789

Query: 1482 FPLVPESLLKLQQQQLLLPFYLHDLKVGPKLTLAG------------PAPVLSLPAATPP 1529
             PLV    L     QLL     H     P  +  G            P P    P   PP
Sbjct: 790  LPLV----LPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPP---PPPPPP 842

Query: 1530 PPPQPPKAELAEREWERPPMAKEGNEAGPSSPPDPLPNEAARTAAKALLENFGFELVIQY 1589
            PPP P + E   R          G E  P++P   L  E +     A+ E  G       
Sbjct: 843  PPPMPLQLEAHLR--------SHGLE--PAAPSPRLRPEESLDPPGAMQELLG------- 885

Query: 1590 NEGKQAVPPPPTPPPPEALGGGDKLACGACGKLFSNMLILKTHEEHVHRRFLPFEALSRY 1649
                      P PP P   G G      + GK  +      + +     RF+P  ++   
Sbjct: 886  -------ALEPLPPAPGDTGVGPP---NSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFP 935

Query: 1650 AAQFRKSYDSLYPPLAE-----------PPKPPDGSLDSPVPHLGPPFLVPEPEAGGTRA 1698
             +  +    S +P + E              PP+   D P    GPP   P P A     
Sbjct: 936  DSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGD-PKAGAGPP---PGPPAYDPYG 991

Query: 1699 PEERSRAGGHWPIEEEESSRGNLPPLVPA 1727
            P    RA G  P         N PP +P+
Sbjct: 992  PYCPGRASGAGPETPGLGLDPNKPPELPS 1020



 Score = 40.4 bits (93), Expect = 0.024
 Identities = 48/176 (27%), Positives = 56/176 (31%), Gaps = 31/176 (17%)

Query: 1403 SVLHQTRSRGTKTDSKIEGPERSQEEPKEGETE--GEVGTEKKGPDTSGFISGLPFLSPP 1460
            S L      G K  S  +GP  +      G     G       G      +   P  +PP
Sbjct: 1403 SALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPP 1462

Query: 1461 PPPLDLHRFPAPLFTPPVLPPFPLVPESLLKLQQQQLLLPFYLHDLKVGPKLTLAGPAPV 1520
            P P      P P   PP  PP P +P          L+ P         P      P P 
Sbjct: 1463 PAPT-----PQPQPPPPPPPPQPALPSP------PPLVAPT--------PSSPPPPPLPP 1503

Query: 1521 LSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPSSPPDP-LPNEAARTAAK 1575
               PA   PPPP PP A          P+A    E    SP DP LP+      AK
Sbjct: 1504 PPPPAMPSPPPPPPPAA---------APLAAPPEEPAAPSPEDPELPDTRPLHLAK 1550



 Score = 39.7 bits (91), Expect = 0.041
 Identities = 26/80 (32%), Positives = 32/80 (40%), Gaps = 6/80 (7%)

Query: 1220 PLEGPNLTPEASPDPLPEPPLASVEVPDKPSGSPGQPPSPAPSPVPEPDAQAEDVAPPPT 1279
            PL G    P A+ +  PEPPL   + P  P  +P   P P P P P   A     +PPP 
Sbjct: 1435 PLPG---LPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALP---SPPPL 1488

Query: 1280 MAEEEEGTTGELRSAEPAPA 1299
            +A              P PA
Sbjct: 1489 VAPTPSSPPPPPLPPPPPPA 1508



 Score = 38.9 bits (89), Expect = 0.070
 Identities = 53/182 (29%), Positives = 67/182 (36%), Gaps = 22/182 (12%)

Query: 2054 TPGGVPSPAVKPPATATPASLP-KFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQ 2112
            TP   P P   PP    P  LP +FNLL           A ++ +P   Y  +  A GP 
Sbjct: 224  TPPYRPGPPDPPPP---PRHLPTQFNLL---ASSSAAAAAAEQSSPQL-YNFSGAAPGPP 276

Query: 2113 P--FLPPGKEATTPTPEPPLPLLPPPPPSEEE--------GPEEPPKASPESEACS-LSA 2161
            P     P ++      + P    PPPPP            G   P      + ACS L  
Sbjct: 277  PPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGG 336

Query: 2162 GDLSDSSAS-SLAEPE--SPGAGGTSGGPGGGTGVPDGMGQRRYRTQMSSLQLKIMKACY 2218
            G+ S  +   S A P   + GA G + GP    G   G G   YR  + S   K  K  Y
Sbjct: 337  GEPSPGAGEPSKAGPSGATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGY 396

Query: 2219 EA 2220
             A
Sbjct: 397  GA 398



 Score = 38.9 bits (89), Expect = 0.070
 Identities = 69/267 (25%), Positives = 90/267 (33%), Gaps = 67/267 (25%)

Query: 1969 EDGSLSPTGSEAGGGGEGEPPRDKRLRTTILPEQL--EILYRWYMQDSNPTRKMLD---C 2023
            EDG+   +    G GG G PP          P +L  E   R+++Q    T   LD    
Sbjct: 664  EDGAADASKGLGGSGGAGGPPGT--------PYELAKEDPQRYHLQSVIRTSASLDEGAT 715

Query: 2024 ISEEVGLKKRVVQVWFQNTRARERKGQFRSTPGGVPSPAVK------------------P 2065
             + E+GL +       +  +  ER G+   TP G+ +  V                   P
Sbjct: 716  AALELGLGRLK-----EKKKGPERGGE---TPEGLATSVVHYGAGAKELGAFLQKSPPPP 767

Query: 2066 PATATPASLPKFNLLLGKVDDGTGREAPKREAPAFPYPT-ATLASGPQP----------F 2114
            P TA         LLL    +  G + P    P  P    + L+  P P           
Sbjct: 768  PPTAQSTQPTPHGLLL----EAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHL 823

Query: 2115 LPPGKEATTPTPEPPLPLLPPPPPSEEEG--------PEEP-PKASPESEACSLSAGDLS 2165
            L P      P P PP P  PPP P + E         P  P P+  PE    SL      
Sbjct: 824  LEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEE---SLDPPGAM 880

Query: 2166 DSSASSLAEPESPGAGGTSGGPGGGTG 2192
                 +L EP  P  G T  GP    G
Sbjct: 881  QELLGAL-EPLPPAPGDTGVGPPNSEG 906



 Score = 38.9 bits (89), Expect = 0.070
 Identities = 33/106 (31%), Positives = 39/106 (36%), Gaps = 21/106 (19%)

Query: 1217 LLSPLEGPNLTPEA-SPDPLPEPPLASVEV----PDKPSGSPGQPPSPAPSPVPEP---- 1267
            L+ P   P L P   S  P P P  + V V    P    G+P  PP P P P P P    
Sbjct: 792  LVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLE 851

Query: 1268 ----DAQAEDVAPPPTMAEEE--------EGTTGELRSAEPAPADS 1301
                    E  AP P +  EE        +   G L    PAP D+
Sbjct: 852  AHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDT 897



 Score = 37.4 bits (85), Expect = 0.20
 Identities = 28/75 (37%), Positives = 33/75 (44%), Gaps = 15/75 (20%)

Query: 1220 PLEGPNLTPEASPDPLPEPPLASV----EVPDKPS----GSPGQP-----PSPAPSPVPE 1266
            PL GP  T  ++PD  P  P A+V     +P  PS    G+P  P     P P P P P 
Sbjct: 1409 PLAGPKDT--STPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPT 1466

Query: 1267 PDAQAEDVAPPPTMA 1281
            P  Q     PPP  A
Sbjct: 1467 PQPQPPPPPPPPQPA 1481



 Score = 37.0 bits (84), Expect = 0.26
 Identities = 74/338 (21%), Positives = 110/338 (32%), Gaps = 58/338 (17%)

Query: 2327 PAPEA-PPALKAPPATTPASMPLGA---APTLPRLAPVLLSGPALAQPPL-----GNLAP 2377
            P P+  P  L   P+ +P++  +G     P     AP     P    PP+      +L  
Sbjct: 797  PPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRS 856

Query: 2378 FNSGPAASSGLLGLATSVLPTTTVVQTAGPGRPLPQRPMPDQTNTSTAGTTDPVPGPPTE 2437
                PAA S  L    S+ P   + +  G   PLP  P P  T            GPP  
Sbjct: 857  HGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLP--PAPGDTGV----------GPPNS 904

Query: 2438 PLGDKVSSERKPVAGPTSSSN----------DAL--KNLKALKTTVPALLGG----QFLP 2481
               D   + R P    T +            D+L     ++   T+  + GG     +  
Sbjct: 905  EGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGK 964

Query: 2482 FPLP-----PAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNP----------MIPQTL 2526
               P     P  G  PP   GP     Y     G   G  P  P           +P T 
Sbjct: 965  AGPPEDEGDPKAGAGPPP--GPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPST- 1021

Query: 2527 IGLLPNALLQPPPQPPEPTATAPPKPPELPAPGEGEAGEVDELLTGSTGISTVDVTHRYL 2586
            +   P  L+Q  P    P    PP PP  PA  E + G    +   +     +  +  +L
Sbjct: 1022 VNAEPLGLIQSGPHQAAPPPPPPPPPPPAPA-SEPKGGLTSPIFCSTKPKKLLKTSSFHL 1080

Query: 2587 CRQCKMAFDGEAPATAHQRSFCFFGRGSGGSMPPPLRV 2624
             R+    F  + P   + + + F        +P  +R+
Sbjct: 1081 LRRRDPPF--QTPKKLYAQEYEFEADEDKADVPADIRL 1116



 Score = 35.8 bits (81), Expect = 0.59
 Identities = 20/67 (29%), Positives = 28/67 (41%), Gaps = 3/67 (4%)

Query: 1235 LPEPPLASVEVPDKPSGSPGQPPSPAPSPVP---EPDAQAEDVAPPPTMAEEEEGTTGEL 1291
            L +PPLA  +    P G P  P +  P P P    P A +     PP + E+   T    
Sbjct: 1405 LDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPA 1464

Query: 1292 RSAEPAP 1298
             + +P P
Sbjct: 1465 PTPQPQP 1471



 Score = 35.0 bits (79), Expect = 1.0
 Identities = 60/226 (26%), Positives = 73/226 (32%), Gaps = 21/226 (9%)

Query: 2348 LGAAPTLPRLAPVLLSGPALAQPPLGNLAPFNSGPAASSGLLGLATSVLPTTTVVQTAGP 2407
            LG A   P   P    GP    PP  +L    +  A+SS     A    P       A P
Sbjct: 214  LGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAP 273

Query: 2408 GRPLPQRPMPDQTNT-----STAGTTDPVPGPPTEPLGDKVSSERKPVAGPTSSSNDALK 2462
            G P P+R +P Q          A    P P PP   L   +S       G +  S     
Sbjct: 274  GPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLS------CGGSYPSMGHRA 327

Query: 2463 NLKALKTTVPALLGGQFLPFPLPPAGGTAPPA--VFGPQLQGAYFQQLYGMKKGLFPMNP 2520
            NL            G   P    P+G TA  +    GP+  G       G   G     P
Sbjct: 328  NLACSPLGGGEPSPGAGEPSKAGPSGATAGASGRATGPEAAGG-----GGAGGGGGGYRP 382

Query: 2521 MI--PQTLIGLLP-NALLQPPPQPPEPTATAPPKPPELPAPGEGEA 2563
            +I  P    G     A      +PP P +TA PK   L  P    A
Sbjct: 383  IIQSPGYKTGKGGYGAAAGGATRPPPPRSTATPKCQSLGGPAAAYA 428



 Score = 33.9 bits (76), Expect = 2.2
 Identities = 15/28 (53%), Positives = 17/28 (60%), Gaps = 1/28 (3%)

Query: 604  LPLGLPPGLMGPGPPPPPGATP-TSPPE 630
            LP   PP +  P PPPPP A P  +PPE
Sbjct: 1501 LPPPPPPAMPSPPPPPPPAAAPLAAPPE 1528



 Score = 33.5 bits (75), Expect = 2.9
 Identities = 32/115 (27%), Positives = 41/115 (35%), Gaps = 11/115 (9%)

Query: 608  LPPGLMGPGPPPPPG-----ATPTSPPELFQYFGPQA-----LGQPQTPLAGPGLRPDKP 657
            L P    PGPPP PG     +  T  P L +   P         QPQ P   P  +P  P
Sbjct: 1424 LAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALP 1483

Query: 658  LEAQLLLNGFHHVGAPARKFPTSAPGSLSPDAHLPPSQLLGSSSDSLPTSPPPDD 712
                L+         P    P   P   SP    PP+    ++    P +P P+D
Sbjct: 1484 SPPPLVAPTPSSPPPPPLP-PPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPED 1537



 Score = 32.0 bits (71), Expect = 8.5
 Identities = 22/58 (37%), Positives = 24/58 (41%), Gaps = 8/58 (13%)

Query: 2325 LAPAPEAPPALKAPPATTPASMPLGAAPTLPRLAPVLLSGPALAQPPLGNLAPFNSGP 2382
            +AP P +PP    PP   PA MP    P  P  AP       LA PP    AP    P
Sbjct: 1489 VAPTPSSPPPPPLPPPPPPA-MPSPPPPPPPAAAP-------LAAPPEEPAAPSPEDP 1538



 Score = 32.0 bits (71), Expect = 8.5
 Identities = 21/72 (29%), Positives = 32/72 (44%), Gaps = 10/72 (13%)

Query: 1224 PNLTPEASPDPLPEPPLASVEVPDKPSGSPGQPPSPAPSPVPEPD------AQAEDVAPP 1277
            P   P A P P P PP A+  +    +  P +P +P+P     PD      A+ ++ A  
Sbjct: 1502 PPPPPPAMPSPPPPPPPAAAPL----AAPPEEPAAPSPEDPELPDTRPLHLAKKQETAAV 1557

Query: 1278 PTMAEEEEGTTG 1289
                +EE G +G
Sbjct: 1558 CGETDEEAGESG 1569


>gi|50083287 LIM homeobox 8 [Homo sapiens]
          Length = 356

 Score = 73.2 bits (178), Expect = 3e-12
 Identities = 52/154 (33%), Positives = 74/154 (48%), Gaps = 6/154 (3%)

Query: 1964 LKRKHEDGS-LSPTGSEAGGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLD 2022
            LKR+ E+G+ +S  G+         P   KR RT+   +QL+++   + QD+NP  + L 
Sbjct: 197  LKREVENGNGISVEGALLTEQDVNHPKPAKRARTSFTADQLQVMQAQFAQDNNPDAQTLQ 256

Query: 2023 CISEEVGLKKRVVQVWFQNTRARERKGQFRSTPGGVPSPAVKPPATATPASLPKFNLLLG 2082
             ++E  GL +RV+QVWFQN RAR +K    +     P  AV PP+  +P  L +      
Sbjct: 257  KLAERTGLSRRVIQVWFQNCRARHKKHVSPNHSSSTPVTAV-PPSRLSPPMLEEMAYSAY 315

Query: 2083 KVDDGTGREAPKREAPAFPYPTATLASGPQPFLP 2116
               DGT   A      A    T     G QP LP
Sbjct: 316  VPQDGTMLTALHSYMDAHSPTTL----GLQPLLP 345



 Score = 54.3 bits (129), Expect = 2e-06
 Identities = 26/57 (45%), Positives = 36/57 (63%)

Query: 2200 RRYRTQMSSLQLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKK 2256
            +R RT  ++ QL++M+A +     P  Q  + L E  GL +RVIQVWFQN RA+ KK
Sbjct: 226  KRARTSFTADQLQVMQAQFAQDNNPDAQTLQKLAERTGLSRRVIQVWFQNCRARHKK 282



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 25/71 (35%), Positives = 37/71 (52%)

Query: 1726 PAGRRFSRTKFTEFQTQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKAR 1785
            P   + +RT FT  Q Q +Q+ F     P    +++LA   GL+ RV+ VWFQN R + +
Sbjct: 222  PKPAKRARTSFTADQLQVMQAQFAQDNNPDAQTLQKLAERTGLSRRVIQVWFQNCRARHK 281

Query: 1786 KNACEGGSMPT 1796
            K+     S  T
Sbjct: 282  KHVSPNHSSST 292


>gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Homo
            sapiens]
          Length = 406

 Score = 72.8 bits (177), Expect = 4e-12
 Identities = 77/308 (25%), Positives = 113/308 (36%), Gaps = 24/308 (7%)

Query: 2141 EEGPEEPPKASPESEACSLSAGDLSDSSASSLAEPESPGAGGT--SGGPGGGTGVPDGMG 2198
            E+  EEPP   PE +       +L         EP      G   + GP    G      
Sbjct: 83   EQQQEEPPLTKPEQQQEEPPLLELKQEQE----EPPQTTVEGPQPAEGPQTAEGPQPPER 138

Query: 2199 QRRYRTQMSSLQLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAK 2258
            +RR RT  +  QL+ ++  ++  + P +   E L   + L +  +QVWFQN RAK K+ +
Sbjct: 139  KRRRRTAFTQFQLQELENFFDESQYPDVVARERLAARLNLTEDRVQVWFQNRRAKWKRNQ 198

Query: 2259 ----LQGTAAGSTGGSSEGLLAAQRTDCPYCDVKYDFYVSCRGHLFSRQHLAKLKEAVRA 2314
                L+ TA        +  L       P  D     ++           + +L      
Sbjct: 199  RVLMLRNTATADLAHPLDMFLGGAYYAAPALDPALCVHL-----------VPQLPRPPVL 247

Query: 2315 QLKSESKCYDLAPAPEAPPALKAPP-ATTPASMPLGAAPTLPRLAPVLLSGPALAQPPLG 2373
             +        + P P  PP    PP A  P    +   P  PR+APV    P    PP  
Sbjct: 248  PVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPWP 307

Query: 2374 NLAPFNSGPAASSGLLGLATSVLPTTTVVQTAGPGRPL-PQRPMPDQTNTSTAGTTDPV- 2431
             +AP  +GP  +    G   + +P    +    PG P+ P  P P            P+ 
Sbjct: 308  PMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLPPGPPMAPLPPGPPMAPLP 367

Query: 2432 PGPPTEPL 2439
            PGPP  PL
Sbjct: 368  PGPPMAPL 375



 Score = 62.0 bits (149), Expect = 8e-09
 Identities = 43/126 (34%), Positives = 61/126 (48%), Gaps = 17/126 (13%)

Query: 1662 PPLAEPPKPPDGSLDSPVPHLGPPFLVPEPEAGGTRAPEERSRAGGHWPIEEEESSRGNL 1721
            PPL +P +  +           PP L  + E    +    ++   G  P E  +++ G  
Sbjct: 89   PPLTKPEQQQEE----------PPLLELKQE----QEEPPQTTVEGPQPAEGPQTAEGPQ 134

Query: 1722 PPLVPAGRRFSRTKFTEFQTQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNAR 1781
            PP     +R  RT FT+FQ Q L++FF+ S YP     ERLA+ L L    V VWFQN R
Sbjct: 135  PP---ERKRRRRTAFTQFQLQELENFFDESQYPDVVARERLAARLNLTEDRVQVWFQNRR 191

Query: 1782 QKARKN 1787
             K ++N
Sbjct: 192  AKWKRN 197



 Score = 56.2 bits (134), Expect = 4e-07
 Identities = 79/320 (24%), Positives = 106/320 (33%), Gaps = 73/320 (22%)

Query: 1841 RGEEEEEVEEEEVEEEQGLEPPAGPEGPLPEPPDGEELSQAEATKAGGKEPEEKATPSPS 1900
            RG E+EE    + E     E   G EG +P      E         GG EPE++    P 
Sbjct: 39   RGGEDEENTRSKPEYGTEAENNVGTEGSVPSDDQDRE-------GGGGHEPEQQQEEPP- 90

Query: 1901 PAHTCDQCAISFSSQDLLTSHRRLHFLPSLQPSAPPQLLDLPLLVFGERNPLVAATSPMP 1960
                             LT        P  Q   PP L    L    E  P      P P
Sbjct: 91   -----------------LTK-------PEQQQEEPPLL---ELKQEQEEPPQTTVEGPQP 123

Query: 1961 GPPLKRKHEDGSLSPTGSEAGGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKM 2020
                          P  +E    G   P R +R RT     QL+ L  ++ +   P    
Sbjct: 124  AE-----------GPQTAE----GPQPPERKRRRRTAFTQFQLQELENFFDESQYPDVVA 168

Query: 2021 LDCISEEVGLKKRVVQVWFQNTRARERKGQFRSTPGGVPSPAVKPPATATPASLPKFNLL 2080
             + ++  + L +  VQVWFQN RA+ ++ Q            +    TAT       ++ 
Sbjct: 169  RERLAARLNLTEDRVQVWFQNRRAKWKRNQ----------RVLMLRNTATADLAHPLDMF 218

Query: 2081 LGKVDDGTGREAPKRE-------APAFPYPTATLASGPQPFLPPGKEATTPTPEPPLPLL 2133
            LG    G    AP  +        P  P P   L   P P  PP        P  P+P +
Sbjct: 219  LG----GAYYAAPALDPALCVHLVPQLPRP-PVLPVPPMPPRPPMVPMPPRPPIAPMPPM 273

Query: 2134 PPPPPSEEEGPEEP-PKASP 2152
             P PP     P  P P+ +P
Sbjct: 274  APVPPGSRMAPVPPGPRMAP 293



 Score = 33.5 bits (75), Expect = 2.9
 Identities = 38/141 (26%), Positives = 56/141 (39%), Gaps = 33/141 (23%)

Query: 1450 FISGLPFLSPP-PPPLDLHRFPAPLFTPPVLPPFPLVPE-SLLKLQQQQLLLPF------ 1501
            F+ G  + +P   P L +H  P  L  PPVLP  P+ P   ++ +  +  + P       
Sbjct: 218  FLGGAYYAAPALDPALCVHLVPQ-LPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPV 276

Query: 1502 ----YLHDLKVGPKLTLAGPAPVLS--------LPAATPPP----PPQPPKAELAEREWE 1545
                 +  +  GP++    P P ++         P  T PP    PP PP A +      
Sbjct: 277  PPGSRMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVP----P 332

Query: 1546 RPPMAKEGNEAGPSSPPDPLP 1566
             PPMA+      P  P  PLP
Sbjct: 333  GPPMAR----VPPGPPMAPLP 349



 Score = 32.0 bits (71), Expect = 8.5
 Identities = 20/48 (41%), Positives = 22/48 (45%), Gaps = 6/48 (12%)

Query: 2517 PMNPMIPQTLIGLLPNALLQPP-----PQPPEPT-ATAPPKPPELPAP 2558
            PM PM P+  I  +P     PP     P PP P  A  PP PP  P P
Sbjct: 257  PMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWPPMAPVP 304


>gi|152963644 paired-like homeodomain transcription factor 1 [Homo
            sapiens]
          Length = 314

 Score = 70.1 bits (170), Expect = 3e-11
 Identities = 69/242 (28%), Positives = 104/242 (42%), Gaps = 32/242 (13%)

Query: 2129 PLPLLPPPPPSEEEGPE------EPPKASPESEACSLSAGDLSDSSASSLAE-PESPGAG 2181
            P  L PPPPP  + GP         P+   E+ A   S  +L +       + PE  GAG
Sbjct: 14   PEGLRPPPPPPHDMGPAFHLARPADPREPLENSASESSDTELPEKERGGEPKGPEDSGAG 73

Query: 2182 GTSGGPGGGTGVPDGMGQRRYRTQMSSLQLKIMKACYEAYRTPTMQECEVLGEEIGLPKR 2241
            GT  G GG         QRR RT  +S QL+ ++A ++  R P M   E +     L + 
Sbjct: 74   GT--GCGGADDPAKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEP 131

Query: 2242 VIQVWFQNARAKEKKAKLQGTAAGSTGG---SSEGLLAAQRTDCPYCDVKYDFYVSCRGH 2298
             ++VWF+N RAK +K +         GG      GL+       PY D      V   G+
Sbjct: 132  RVRVWFKNRRAKWRKRERNQQLDLCKGGYVPQFSGLVQ------PYED------VYAAGY 179

Query: 2299 LFSRQHLAKLKEAVRAQLKSESKCYDLAPAPEAPPALKAPPA-----TTPASMPLGAAPT 2353
             ++       K    A L ++S  +  + +P +  ++ + P+     T P+SM  GA P 
Sbjct: 180  SYNNW---AAKSLAPAPLSTKSFTFFNSMSPLSSQSMFSAPSSISSMTMPSSMGPGAVPG 236

Query: 2354 LP 2355
            +P
Sbjct: 237  MP 238



 Score = 55.5 bits (132), Expect = 7e-07
 Identities = 49/157 (31%), Positives = 63/157 (40%), Gaps = 23/157 (14%)

Query: 1662 PPLAEPPKPPDGSLDSPVPHLGPPFLVPEP------EAGGTRAPEERSRAGGHWPIEEEE 1715
            P    PP PP   +  P  HL  P    EP      E+  T  PE+     G  P   E+
Sbjct: 14   PEGLRPPPPPPHDM-GPAFHLARPADPREPLENSASESSDTELPEKER---GGEPKGPED 69

Query: 1716 SSRGNL------PPLVPAGRRFSRTKFTEFQTQALQSFFETSAYPKDGEVERLASLLGLA 1769
            S  G         P     +R  RT FT  Q Q L++ F+ + YP     E +A    L 
Sbjct: 70   SGAGGTGCGGADDPAKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLT 129

Query: 1770 SRVVVVWFQNARQKARK-------NACEGGSMPTGGG 1799
               V VWF+N R K RK       + C+GG +P   G
Sbjct: 130  EPRVRVWFKNRRAKWRKRERNQQLDLCKGGYVPQFSG 166



 Score = 44.7 bits (104), Expect = 0.001
 Identities = 35/107 (32%), Positives = 49/107 (45%), Gaps = 7/107 (6%)

Query: 1949 RNPLVAATSPMPGPPLKRKHEDGS-LSPTGSEAGG---GGEGEPPRDK---RLRTTILPE 2001
            R PL  + S      L  K   G    P  S AGG   GG  +P + K   R RT    +
Sbjct: 40   REPLENSASESSDTELPEKERGGEPKGPEDSGAGGTGCGGADDPAKKKKQRRQRTHFTSQ 99

Query: 2002 QLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQNTRARERK 2048
            QL+ L   + ++  P   M + I+    L +  V+VWF+N RA+ RK
Sbjct: 100  QLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRK 146


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 1124

 Score = 69.3 bits (168), Expect = 5e-11
 Identities = 86/281 (30%), Positives = 105/281 (37%), Gaps = 44/281 (15%)

Query: 2327 PAPEAPPALKAPPATTPASMPLGAAPTLPRLAPVLLSGPAL-------AQPPLGNLA-PF 2378
            P P+APPAL +PP     S PL    T P  AP  L+ P L       A PPL  LA P 
Sbjct: 590  PPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPS 649

Query: 2379 NSGPAASSGLLGLATSVLPTTTVVQT--AGPGRP--LPQRPMPDQTNTSTAGTTDPVP-- 2432
               P A +  L  A    P +  VQ   + P  P   P    P Q   S A     VP  
Sbjct: 650  PQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPS 709

Query: 2433 ---GPPTEPLGDKVSSERKPVAG------PTSSSNDALKNLKALKTTVPALLGGQFLPF- 2482
                PP  P          P+A       P+  ++  +         VP LL    L   
Sbjct: 710  PPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVP 769

Query: 2483 PLPPAG----------GTAPPAVFGPQLQ------GAYFQQLYGMKKGLFPMNPMI--PQ 2524
            P PPA             APPA+  P LQ       ++  Q         PM+P+   P 
Sbjct: 770  PSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPP 829

Query: 2525 TLIGLLPNALLQPPPQPP-EPTATAPPKPPELPAPGEGEAG 2564
                +L   LLQ PP PP  PT  AP +PP  P P    +G
Sbjct: 830  QAPPVLAAPLLQVPPSPPASPTLQAPRRPP-TPGPDTSVSG 869



 Score = 62.4 bits (150), Expect = 6e-09
 Identities = 74/267 (27%), Positives = 103/267 (38%), Gaps = 46/267 (17%)

Query: 2327 PAPEAPPALK---APPATTPASMP-------LGAAPTLPRLAPVL----LSGPALAQPPL 2372
            P+P APP+L+   +PPAT P+  P       + A P+L  + P+     L+ P+L  PP 
Sbjct: 346  PSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPP- 404

Query: 2373 GNLAPFNSGPAASSGL---LGLATSVLPTTTVVQTAGPGRPLPQRPMPDQTNTSTAGTTD 2429
                     P A S L     L +  L  T    T  P +       P +   ST   + 
Sbjct: 405  --------SPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRP-ASTPPDSP 455

Query: 2430 PVPGPPTEPLGDKVSSERKPVAGPTSS--SNDALKNLKALKTTVP-ALLGGQFLPFPL-- 2484
            P+  P + P    + +   P   P SS  +   L+ L +L +  P A L    +P PL  
Sbjct: 456  PLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMP-PLET 514

Query: 2485 -----------PPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNPMIPQTL-IGLLPN 2532
                       PPA  T PP    P L     Q             P  P    +   P+
Sbjct: 515  QSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPS 574

Query: 2533 ALLQPPPQPPEPTATAPPK-PPELPAP 2558
             L  PPP+ P   AT PP+ PP L +P
Sbjct: 575  PLTTPPPETPSSIATPPPQAPPALASP 601



 Score = 56.6 bits (135), Expect = 3e-07
 Identities = 72/245 (29%), Positives = 94/245 (38%), Gaps = 26/245 (10%)

Query: 2326 APAP-EAPPA-LKAPPATTPASMPLGAAPTLPRLAPVLLSGPALAQPPLGNLAPFNSGPA 2383
            AP P +APP+ L  PP  TP+S+      T P  AP  L+ P L   P   L+P  + P 
Sbjct: 565  APCPLQAPPSPLTTPPPETPSSI-----ATPPPQAPPALASPPLQGLPSPPLSPLATPPP 619

Query: 2384 ASSGLLGLATSVLPTTTVVQTAGPGRPLPQRPMPDQTNTSTAGTTD-PVPGPPTEPLGDK 2442
             +   L L     P +     + P  PL   P P   N         P   PP+ P+   
Sbjct: 620  QAPPXLALPPLQAPPSP--PASPPLSPL-ATPSPQAPNALAVHLLQAPFSPPPSPPVQAP 676

Query: 2443 VSSERKPVAGPTSS-SNDALKNLKALKTTVPALLGGQFLPFPLPPAGGTAPPAVFGPQLQ 2501
             S    P   P+++  + A  +L A    VP        P   PP   +A P    P   
Sbjct: 677  FSPPASPPVSPSATPPSQAPPSLAAPPLQVPP------SPPASPPMSPSATPPPQAPPPL 730

Query: 2502 GAYFQQLYGMKKGLFPMNPMI--PQTLIGLLPNALLQPPPQPP-----EPTATAPPK-PP 2553
             A   Q+        PM+P    P  +  LL    LQ PP PP      P A  PP+ PP
Sbjct: 731  AAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPP 790

Query: 2554 ELPAP 2558
             L  P
Sbjct: 791  ALATP 795



 Score = 55.5 bits (132), Expect = 7e-07
 Identities = 117/491 (23%), Positives = 153/491 (31%), Gaps = 94/491 (19%)

Query: 1220 PLEGPNLTPEASPDPLPEPPLASVEVPDKPSGSPGQPPS--PAPSPVPEPDAQAEDVAPP 1277
            P+  P+      P  LP  P  +  +P  P  SP  PPS    PSP   P +QA     P
Sbjct: 316  PVPPPDNAATPLPATLPPSPPLATPLPLAPP-SPSAPPSLQTLPSPPATPPSQA-----P 369

Query: 1278 PTMAEEEEGTTGELRSAEP--APADSRHPLTYRKTTNFALDKFLDPARPYKCTVCKESFT 1335
            P+M          L++  P   P     P      +  AL                 S  
Sbjct: 370  PSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSL----------QATTSLG 419

Query: 1336 QKNILLVHYNSVSHLHKMKKAAIDPSAPARGEAGAPP---TTTAATDKPFKCTVCRVSYN 1392
               +   H        + + +   PS PA     +PP     +     P + ++      
Sbjct: 420  SPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSP 479

Query: 1393 QSSTLEIHMRSVLHQTRSRGTKT--DSKIEGPERSQEEPKEGETEGEVGTEKKGPDTSGF 1450
             SS L IH    L    S   +    S I  P  +Q        +    +    P     
Sbjct: 480  LSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPP----- 534

Query: 1451 ISGLPFLSPPPPPLDLHRFPAPLFTPPV-LPPFPLVPESLLKLQQQQLLLPFYLHDLKVG 1509
            +  LP L+PPP    L    APL TP +  PP P                          
Sbjct: 535  LENLPSLAPPP----LQTASAPLTTPHLETPPCP-------------------------A 565

Query: 1510 PKLTLAGPAPVLSLPAATP----PPPPQPPKAELAEREWERPPMAKEGNEAGPSSPPDPL 1565
            P    A P+P+ + P  TP     PPPQ P A  +      PP+  +G  + P SP    
Sbjct: 566  PCPLQAPPSPLTTPPPETPSSIATPPPQAPPALAS------PPL--QGLPSPPLSPLATP 617

Query: 1566 PNEAARTAAKALLENFGFELVIQYNEGKQAVPPPPTPPPPEALGGGDKLACGACGKLFSN 1625
            P +A    A   L               QA P PP  PP   L      A  A       
Sbjct: 618  PPQAPPXLALPPL---------------QAPPSPPASPPLSPLATPSPQAPNALAVHLLQ 662

Query: 1626 MLILKTHEEHVHRRFLP--FEALSRYAAQFRKSYDSL-YPPLAEPPKPPDGSLDS----P 1678
                      V   F P     +S  A    ++  SL  PPL  PP PP     S    P
Sbjct: 663  APFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP 722

Query: 1679 VPHLGPPFLVP 1689
             P   PP   P
Sbjct: 723  PPQAPPPLAAP 733



 Score = 53.5 bits (127), Expect = 3e-06
 Identities = 99/405 (24%), Positives = 138/405 (34%), Gaps = 57/405 (14%)

Query: 2326 APAPEAPPALKAPPATTPASMPLGAAPTLPRLAPVLLSGPALAQP-------PLGNLA-- 2376
            AP P A P L+ PP + PAS P+  + T P   P LL+ P L  P       P+  LA  
Sbjct: 726  APPPLAAPPLQVPP-SPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKP 784

Query: 2377 PFNSGPAASSGLLGLATSVLPTTTVVQTAGPGRPLPQRPM----PDQTNTSTAGTTDPVP 2432
            P  + PA ++  L    S   +        P   LP  P+    P       A      P
Sbjct: 785  PPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPP 844

Query: 2433 GPPTEPLGDKVSSERKPVAGPTSSSNDALKNLKALKTTVPALLGGQFLPFPLPPAGGTAP 2492
             PP  P     +  R P  GP +S +     L                P P PP   +  
Sbjct: 845  SPPASP--TLQAPRRPPTPGPDTSVSGPRLTL-------------ALAPGPPPPPSRSPS 889

Query: 2493 PAVFGPQLQG------AYFQQLYGM---KKGLFPMNPMIPQTLIGLLPNALLQPPPQPPE 2543
              + GP L G      +  ++L G     +G    +P  P   +     A     P PP 
Sbjct: 890  STLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPP-PDAELAACHPAAWSRGPAPPL 948

Query: 2544 PTATAPPKP-PELPAPGEGEAGEVDELLTGSTGISTVDVTH-RYLCRQCKMAFD-GEAPA 2600
                AP  P P  PA G G A           G+ T+  T           A D G +P 
Sbjct: 949  AFRGAPGAPLPWPPATGPGSA----------DGLCTIYETEGPESATPAPGALDPGPSPG 998

Query: 2601 TAHQRSFCFFGRGSGGSMPPPLR---VPICTYHCLACEVLLSGREALASHLRSSAHRRKA 2657
            T+  ++    G G+    P   R   +P+        + LLS    LA+     A     
Sbjct: 999  TSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAA--AEGAAGGSG 1056

Query: 2658 APPQGGPPISITNAATAASAAVAFAKEEARLPHTDSNPKTTTTST 2702
              P G     +T  A AA +     +    L   D +  + T+ T
Sbjct: 1057 GGPGGAEGGGVTGGARAALSDAELGRWAELLSPLDESRASITSVT 1101



 Score = 50.4 bits (119), Expect = 2e-05
 Identities = 120/506 (23%), Positives = 174/506 (34%), Gaps = 93/506 (18%)

Query: 2094 KREAPAFPYPTATLASGPQPFLPPGKEATTPTPEPPLPLLPPP-------------PPSE 2140
            K +A A     A  A G     PPG      +P PP P+ P               P +E
Sbjct: 7    KAKAGAAARTPAARAPGLLTPRPPG------SPRPPPPVTPAALRVLGAAGAVGRKPLAE 60

Query: 2141 EEG-------PEEPPKASPESEACSLSAGDLSDSSASSLAEPESPGAGGTSGGP------ 2187
              G       PE  P+A P   A + S    S   AS   E  +P A  TS GP      
Sbjct: 61   RAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGE-RAPPAKNTSPGPVSSPGR 119

Query: 2188 GGGTGVPDGMGQRRYRTQMSSLQLKIMKACYEAYRTPTMQ---ECEVLGEEIGLPKRVIQ 2244
              GT  P  +GQ+  R  +S+ +        EA +   +      +  G   G P     
Sbjct: 120  ASGTTRPGPLGQKGLR--ISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTP----- 172

Query: 2245 VWFQNARAKEKKAKLQGTAAGSTGGSSEGLLAAQRTDCPYCDVKYDFYVSCRGHLFSRQH 2304
                 + A  ++++  GT  G     +        T+ P   V      S   H  +   
Sbjct: 173  -----SPAMARRSRAAGTEVG-LPRPAPSARPRPPTEGPRKSVS-----SASEHSTTEPS 221

Query: 2305 LA--KLKEAVRAQLKSESKCYDLAPAPEAPPALKAPPATTPASMPLGAAPTLPRLAPVLL 2362
             A  +   A     +  S+    +  P + PA   P A      P  A P+ P+   +  
Sbjct: 222  PAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAP--AHPSQPKPKGLQA 279

Query: 2363 SGPALAQPPLGNLAPFNSGPAASSGLLGLATSVLPTTTVVQTAGPGRPLPQRPMPDQTNT 2422
              P    PP  + AP   GP +SS          P  T   +    RP+P    PD    
Sbjct: 280  LRPPQVTPPRKDAAP-ALGPLSSS----------PLATPSPSGTKARPVPP---PD---- 321

Query: 2423 STAGTTDPVPGPPTEPLGDKVSSERKPVAGPTSSSNDALKNLKALKTTVPALLGGQFL-- 2480
              A T  P   PP+ PL   +     P+A P+ S+  +L+ L +   T P+         
Sbjct: 322  -NAATPLPATLPPSPPLATPL-----PLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTP 375

Query: 2481 PFPLPPAGGTAPP-----AVFGPQLQGAYFQ-QLYGMKKGLFPMNPMIPQT--LIGLLPN 2532
            P   PP+  T PP     ++  P LQ       L  ++      +P +  T   + + P 
Sbjct: 376  PMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPR 435

Query: 2533 ALLQPPPQPPEPTATAPPKPPELPAP 2558
                    P  P +T P  PP L AP
Sbjct: 436  QTQASLTSPSRPASTPPDSPP-LQAP 460



 Score = 45.4 bits (106), Expect = 7e-04
 Identities = 24/63 (38%), Positives = 32/63 (50%), Gaps = 2/63 (3%)

Query: 1219 SPLEGPNLTPEASPDPLPEPPLAS--VEVPDKPSGSPGQPPSPAPSPVPEPDAQAEDVAP 1276
            SP   P ++P A+P P   PPLA+  ++VP  P  SP   PS  P P   P   A  +  
Sbjct: 709  SPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQV 768

Query: 1277 PPT 1279
            PP+
Sbjct: 769  PPS 771



 Score = 44.3 bits (103), Expect = 0.002
 Identities = 43/136 (31%), Positives = 55/136 (40%), Gaps = 17/136 (12%)

Query: 2058 VPSPAVKPPATAT---PASLPKFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQPF 2114
            +PSP    P  A     ASLP   L            AP  + P  P  + TL +  +P 
Sbjct: 800  LPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRP- 858

Query: 2115 LPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESEACSLSAGDLSDSSASSLAE 2174
              PG + +   P   L L P PPP         P  SP S   +LS  DL+  S+S+ + 
Sbjct: 859  PTPGPDTSVSGPRLTLALAPGPPPP--------PSRSPSS---TLSGPDLAGHSSSATST 907

Query: 2175 PESPGAGGTSGGPGGG 2190
            PE     G   GP GG
Sbjct: 908  PEE--LRGYDSGPEGG 921



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 39/125 (31%), Positives = 47/125 (37%), Gaps = 22/125 (17%)

Query: 2059 PSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQPFLPPG 2118
            PSP V+ P +  PAS P                 P +  P+   P   +   P P  PP 
Sbjct: 669  PSPPVQAPFSP-PASPPV----------SPSATPPSQAPPSLAAPPLQVPPSP-PASPPM 716

Query: 2119 KEATTPTPEPPLPLLPPP---PPSEEEGPEEPPKASPESEACSLSAGDLSDSSASSLAEP 2175
              + TP P+ P PL  PP   PPS    P   P A+P      L A       A  L  P
Sbjct: 717  SPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLA-------APPLQVP 769

Query: 2176 ESPGA 2180
             SP A
Sbjct: 770  PSPPA 774



 Score = 42.4 bits (98), Expect = 0.006
 Identities = 38/116 (32%), Positives = 46/116 (39%), Gaps = 16/116 (13%)

Query: 605 PLGLPPGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRPDKPLEAQLLL 664
           PL  PP    P    PP   P SPP             P +PLA P  +    L   LL 
Sbjct: 613 PLATPPPQAPPXLALPPLQAPPSPPA----------SPPLSPLATPSPQAPNALAVHLLQ 662

Query: 665 NGFHHVGAPARKFPTSAPGS--LSPDAHLPPSQL---LGSSSDSLPTSPPPDDSLS 715
             F    +P  + P S P S  +SP A  PPSQ    L +    +P SPP    +S
Sbjct: 663 APFSPPPSPPVQAPFSPPASPPVSPSA-TPPSQAPPSLAAPPLQVPPSPPASPPMS 717



 Score = 42.0 bits (97), Expect = 0.008
 Identities = 36/132 (27%), Positives = 48/132 (36%), Gaps = 32/132 (24%)

Query: 2057 GVPSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQPFLP 2116
            G+PSP + P AT  P + P   L             P  +AP  P           P  P
Sbjct: 605  GLPSPPLSPLATPPPQAPPXLAL-------------PPLQAPPSP-----------PASP 640

Query: 2117 PGKEATTPTPEPPLPL--------LPPPPPSEEEGPEEPPKASPESEACSLSAGDLSDSS 2168
            P     TP+P+ P  L          PPP    + P  PP + P S + +  +      +
Sbjct: 641  PLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLA 700

Query: 2169 ASSLAEPESPGA 2180
            A  L  P SP A
Sbjct: 701  APPLQVPPSPPA 712



 Score = 40.8 bits (94), Expect = 0.018
 Identities = 87/411 (21%), Positives = 117/411 (28%), Gaps = 66/411 (16%)

Query: 1211 PSSLYFLLSPLEGPNLT--PEASPDPLPEPPLASVEVPDKPSGSPGQPPSPAPSPVPEPD 1268
            P  L    +PL  P+L   P  +P PL  PP      P +   S   PP  AP  +  P 
Sbjct: 543  PPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPP 602

Query: 1269 AQAEDVAPPPTMAEEEEGTTGELR----SAEPAPADSRHPLTYRKTTNFALDKFLDPARP 1324
             Q     P   +A         L      A P+P                      PA P
Sbjct: 603  LQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSP----------------------PASP 640

Query: 1325 YKCTVCKESFTQKNILLVHYNSVSHLHKMKKAAIDPSAPARGEAGAPPTTTAATDKPFKC 1384
                +   S    N L VH                P +P      +P  T  +   P   
Sbjct: 641  PLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLA 700

Query: 1385 TVCRVSYNQSSTLEIHMRSVLHQTRSRGTKTDSKIEGPERS---QEEPKEGETEGEVGTE 1441
                     +  L++          S       +   P  +   Q  P    +     + 
Sbjct: 701  ---------APPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSA 751

Query: 1442 KKGPDTSGFISGLPFLSPPPPPLDLHRFPAPLFTPPVLPPFPLVPESLLKLQQQQLLLPF 1501
               P     ++  P   PP PP  L    +PL  PP   P  L    L  L       P 
Sbjct: 752  TPPPRVPPLLAAPPLQVPPSPPASLPM--SPLAKPPPQAPPALATPPLQALPSPPASFP- 808

Query: 1502 YLHDLKVGPKLTLAGPAPVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPSSP 1561
                     +   +  A +   P ATPPP   P  A    +    PP +       P  P
Sbjct: 809  --------GQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASP--TLQAPRRP 858

Query: 1562 PDPLPNEAARTAAKALLENFGFELVIQYNEGKQAVPPPPTPPPPEALGGGD 1612
            P P P+ +            G  L +    G    PPPP+  P   L G D
Sbjct: 859  PTPGPDTSVS----------GPRLTLALAPGP---PPPPSRSPSSTLSGPD 896



 Score = 40.8 bits (94), Expect = 0.018
 Identities = 37/126 (29%), Positives = 47/126 (37%), Gaps = 18/126 (14%)

Query: 605 PLGLPPGLMGPGPPPPPGATP--TSPPELFQYFGPQALGQPQTPLA----GPGLRPDKPL 658
           PL  PP  + P PP  P  +P  T PP +        L  P +P A     P  +P    
Sbjct: 729 PLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQA 788

Query: 659 EAQLLLNGFHHVGAPARKFPTSAPGSLSPDAHLPPSQL----------LGSSSDSLPTSP 708
              L       + +P   FP  AP   SP A LP S L          L +    +P SP
Sbjct: 789 PPALATPPLQALPSPPASFPGQAP--FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSP 846

Query: 709 PPDDSL 714
           P   +L
Sbjct: 847 PASPTL 852



 Score = 39.3 bits (90), Expect = 0.053
 Identities = 39/127 (30%), Positives = 45/127 (35%), Gaps = 22/127 (17%)

Query: 606 LGLPPGLMGPGPP--PPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRPD--KPLEAQ 661
           L  PP  + P PP  PP   + T PP+         L  P +P A P + P    P    
Sbjct: 699 LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVP 758

Query: 662 LLLNGFHHVGAPARKFPTSAPGSL------------SPDAHLPPSQLLGSSSDSLPTSPP 709
            LL       AP  + P S P SL             P    PP Q L S   S P   P
Sbjct: 759 PLL------AAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAP 812

Query: 710 PDDSLSL 716
              S SL
Sbjct: 813 FSPSASL 819



 Score = 38.1 bits (87), Expect = 0.12
 Identities = 46/172 (26%), Positives = 58/172 (33%), Gaps = 29/172 (16%)

Query: 548 SPPEASLPPSAGDKEPKTKSSWQCKVCSYETNISRNLRIHMTSEKHMQNVLMLHQ-GLPL 606
           +PP  +LPP      P                 S  L    T      N L +H    P 
Sbjct: 621 APPXLALPPLQAPPSPPA---------------SPPLSPLATPSPQAPNALAVHLLQAPF 665

Query: 607 GLPPGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQ-----TPLAGPGLRPDKPLEAQ 661
             PP      P  PP + P SP        P +L  P      +P A P + P      Q
Sbjct: 666 SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 725

Query: 662 LLLNGFHHVGAPARKFPTSAPGS--LSPDAHLPP--SQLLGSSSDSLPTSPP 709
                   + AP  + P S P S  +SP A  PP    LL +    +P SPP
Sbjct: 726 ----APPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPP 773



 Score = 37.0 bits (84), Expect = 0.26
 Identities = 71/323 (21%), Positives = 107/323 (33%), Gaps = 48/323 (14%)

Query: 1862 PAGPEGPLPEPPDGEELSQAEATKAGGKEPEEKATPSPSPAHTCDQCAISFSSQDLLTSH 1921
            P  P  P   PP  + L    AT      P     P  +P     Q          LTS 
Sbjct: 342  PLAPPSP-SAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSL--QTIPPIQVPHSLTS- 397

Query: 1922 RRLHFLPSLQPSAPPQLLDLPLLVFGERNPLVAATSPMPGPPLKRKHEDGSLSPTGSEAG 1981
                  PSLQ  APP  L L  L          AT+ +  P L+  H   ++SP  ++A 
Sbjct: 398  ------PSLQ--APPSPLALSSL---------QATTSLGSPTLQATHSFLTMSPRQTQAS 440

Query: 1982 GGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQN 2041
                  P        +  P+   +     +  S P +  L      +     +  +   +
Sbjct: 441  LTSPSRP-------ASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALS 493

Query: 2042 TRARERKGQFRSTPGGVPSPAVKPP----ATATPASL--PKFNLLLGKVDDGTGREAPKR 2095
            + A         +P    S  + PP    ++  P SL  P  +L    +++      P  
Sbjct: 494  SLASH-------SPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPL 546

Query: 2096 EAPAFPYPTATLASGPQPFLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESE 2155
            +  + P  T  L + P P       A  P   PP PL  PPP +       PP+A P   
Sbjct: 547  QTASAPLTTPHLETPPCP-------APCPLQAPPSPLTTPPPETPSSIATPPPQAPPALA 599

Query: 2156 ACSLSAGDLSDSSASSLAEPESP 2178
            +  L        S  +   P++P
Sbjct: 600  SPPLQGLPSPPLSPLATPPPQAP 622



 Score = 37.0 bits (84), Expect = 0.26
 Identities = 49/188 (26%), Positives = 67/188 (35%), Gaps = 41/188 (21%)

Query: 1471 APLFTPPVLPPFPLVPESLLKLQQQQLLLPFYLHDLKV---GPKLTLAGPAPVLSLPAAT 1527
            +PL TPP   P P++   LL++       P      +    GP  +++GP   L+L    
Sbjct: 822  SPLATPPPQAP-PVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP 880

Query: 1528 PPPPPQPPKAELA-------EREWERPPMAKEGNEAGP------SSPPD----------- 1563
            PPPP + P + L+              P    G ++GP      S PPD           
Sbjct: 881  PPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAW 940

Query: 1564 ---PLPNEAARTAAKALLE--------NFGFELVIQYNEGKQAVPPPP--TPPPPEALGG 1610
               P P  A R A  A L         +      I   EG ++  P P    P P     
Sbjct: 941  SRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTS 1000

Query: 1611 GDKLACGA 1618
            G K A GA
Sbjct: 1001 GGKAAAGA 1008



 Score = 36.6 bits (83), Expect = 0.35
 Identities = 74/323 (22%), Positives = 104/323 (32%), Gaps = 39/323 (12%)

Query: 1861 PPAGPEGPLPEPPDGEELSQAEATKAGGKEPEEKATPSPSPAHTCDQCAISFSSQDLLTS 1920
            PP+    P+  PP  + +   +   +    P  +A PSP    +  Q   S  S  L  +
Sbjct: 369  PPSMTTPPMQAPPSLQTIPPIQVPHSL-TSPSLQAPPSPLALSSL-QATTSLGSPTLQAT 426

Query: 1921 HRRLHFLPSLQPSAPPQLLDLPLLVFGERNPLVAATSPMPGPPLKRKHEDGSLSPTGSEA 1980
            H  L   P  Q  A       P     +  PL A  S    PPL+      SLSP  S  
Sbjct: 427  HSFLTMSPR-QTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQT-----SLSPAVSP- 479

Query: 1981 GGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQ 2040
                         L + +    L+ L    +   +P   +   I   +  +  +     Q
Sbjct: 480  -------------LSSPLTIHPLQALSS--LASHSPQAPLSSLIMPPLETQSSLAPPSLQ 524

Query: 2041 NTRARERKGQFRSTPGGVPSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAF 2100
               A        + P   P     PP     A L   +L           +AP       
Sbjct: 525  TPPASLTTPPLENLPSLAP-----PPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTP 579

Query: 2101 PYPTATLASGPQPFLPPGKEATTPT---PEPPLPLLPPPPPSEEEGPEEPPKASPESEAC 2157
            P  T +  + P P  PP   A+ P    P PPL  L  PPP        PP  +P S   
Sbjct: 580  PPETPSSIATPPPQAPPAL-ASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPA 638

Query: 2158 SLSAGDLSDSSASSLAEPESPGA 2180
            S     L+  S      P++P A
Sbjct: 639  SPPLSPLATPS------PQAPNA 655



 Score = 36.2 bits (82), Expect = 0.45
 Identities = 57/238 (23%), Positives = 79/238 (33%), Gaps = 25/238 (10%)

Query: 14  PSPGHNAPSLPSDTFSSSTPSDPVTKDPPAASSTSENMRSSEPGGQLLESGCGLVPPKEI 73
           PSP   AP  P  +   S  + P ++ PP+ ++    +  S P    +       PP + 
Sbjct: 669 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSA--TPPPQA 726

Query: 74  GEPQEGPDCGHFPPNDPGVEKDKEQEEEEEGLPPMDLSNHLFFTAGGEAYL----VAK-- 127
             P   P     PP+ P              +PP+  +  L       A L    +AK  
Sbjct: 727 PPPLAAPPL-QVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPP 785

Query: 128 ------LSLPGGSELLLPKGFPWGEAGIKEEPSLPF--LAYPPPSH---LTALHIQHGFD 176
                 L+ P    L  P     G+A      SLP   LA PPP     L A  +Q    
Sbjct: 786 PQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPS 845

Query: 177 PIQGFSSSDQILSHDTSAPSPAACEERHGAFWSYQLAPNPPGDPKDGPMGNSGGNHVA 234
           P      +   L      P+P       G   +  LAP PP  P   P     G  +A
Sbjct: 846 P-----PASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLA 898



 Score = 35.0 bits (79), Expect = 1.0
 Identities = 31/97 (31%), Positives = 35/97 (36%), Gaps = 11/97 (11%)

Query: 2061 PAVKPPAT-ATPASLPKFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQPF-LPPG 2118
            P V PP   A PA        LG +              A P P    A+ P P  LPP 
Sbjct: 283  PQVTPPRKDAAPA--------LGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPS 334

Query: 2119 KEATTPTP-EPPLPLLPPPPPSEEEGPEEPPKASPES 2154
                TP P  PP P  PP   +    P  PP  +P S
Sbjct: 335  PPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPS 371



 Score = 34.7 bits (78), Expect = 1.3
 Identities = 34/104 (32%), Positives = 38/104 (36%), Gaps = 27/104 (25%)

Query: 605 PLGLPPGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRPDKPLEAQLLL 664
           PL  PP  +   PP  P +  T PP+      P AL  P  PL G    P  PL      
Sbjct: 568 PLQAPPSPLTTPPPETPSSIATPPPQ-----APPALASP--PLQG---LPSPPL------ 611

Query: 665 NGFHHVGAPARKFPTSAPGSLSPDAHLPPSQLLGSSSDSLPTSP 708
                  +P    P  AP    P   LPP Q   S   S P SP
Sbjct: 612 -------SPLATPPPQAP----PXLALPPLQAPPSPPASPPLSP 644



 Score = 34.7 bits (78), Expect = 1.3
 Identities = 29/105 (27%), Positives = 39/105 (37%), Gaps = 25/105 (23%)

Query: 1219 SPLEGPNLTPEASPDPLPEPPLAS--VEVPDKPSGSPG-----QPPSP------------ 1259
            SP     ++P A+P P   P LA+  ++VP  P  SP      +PP+P            
Sbjct: 814  SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLT 873

Query: 1260 ---APSPVPEPDAQAEDVAPPPTMAEEEEGTTG---ELRSAEPAP 1298
               AP P P P          P +A      T    ELR  +  P
Sbjct: 874  LALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGP 918



 Score = 34.3 bits (77), Expect = 1.7
 Identities = 32/126 (25%), Positives = 41/126 (32%), Gaps = 19/126 (15%)

Query: 2054 TPGGVPSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQP 2113
            +P   P P   PP  A P  +P                +P    P  P  T      P  
Sbjct: 717  SPSATPPPQAPPPLAAPPLQVPP---------------SPPASPPMSPSATPPPRVPPLL 761

Query: 2114 FLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPP-KASPESEACSLSAGDLSDSSA--- 2169
              PP +   +P    P+  L  PPP        PP +A P   A        S S++   
Sbjct: 762  AAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPM 821

Query: 2170 SSLAEP 2175
            S LA P
Sbjct: 822  SPLATP 827



 Score = 33.9 bits (76), Expect = 2.2
 Identities = 30/115 (26%), Positives = 41/115 (35%), Gaps = 12/115 (10%)

Query: 2053 STPGGVP-SPAVKPPATATPA-SLPKFNLLLGKVDDGTGREAPKREAPAFPYPTATLASG 2110
            S P   P SP+  PP+ A P+ + P   +            +P    P  P  T    + 
Sbjct: 678  SPPASPPVSPSATPPSQAPPSLAAPPLQV----------PPSPPASPPMSPSATPPPQAP 727

Query: 2111 PQPFLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESEACSLSAGDLS 2165
            P    PP +   +P   PP+     PPP        PP   P S   SL    L+
Sbjct: 728  PPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLA 782



 Score = 33.1 bits (74), Expect = 3.8
 Identities = 47/161 (29%), Positives = 55/161 (34%), Gaps = 29/161 (18%)

Query: 2053 STPGGVPSPAVKPPATATPASLPKFNLLLGK---VDDGTGREAPKREAPAFPYPTATLAS 2109
            ++PG V SP  +   T  P  L +  L +     V  G   EAPKR A +      T  S
Sbjct: 109  TSPGPVSSPG-RASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDT--S 165

Query: 2110 GPQPFLPP----------GKEATTPTPEPPLPLLPPPP--------PSEEEGPEEPPKAS 2151
            GP P  P           G E   P P P     PP           SE    E  P A 
Sbjct: 166  GPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAAR 225

Query: 2152 PESEA---CSLSAGDLSDSSASSLAEP--ESPGAGGTSGGP 2187
                A       A     SSA+ L+ P    P A GT   P
Sbjct: 226  RRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAP 266



 Score = 33.1 bits (74), Expect = 3.8
 Identities = 27/96 (28%), Positives = 35/96 (36%), Gaps = 19/96 (19%)

Query: 345 PPSPPTATWDPSPTQAKESPVAAGEAGPDWFPEGQEEDGGLCPPLN---------QSSPT 395
           PPSPP         QA  SP A+    P   P  Q       PPL            SP+
Sbjct: 668 PPSPPV--------QAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPS 719

Query: 396 SKEGGTLPAPVGSP--EDPSDPPQPYRLADDYTPAP 429
           +      P P+ +P  + P  PP    ++   TP P
Sbjct: 720 ATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPP 755



 Score = 32.7 bits (73), Expect = 5.0
 Identities = 30/111 (27%), Positives = 40/111 (36%), Gaps = 1/111 (0%)

Query: 605 PLGLPPGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRPDKPLEAQLLL 664
           P   PP +  P    PP      P ++       +L  P +PLA   L+    L +  L 
Sbjct: 365 PSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQ 424

Query: 665 NGFHHVGAPARKFPTSAPGSLSPDAHLPPSQLLGSSSDSLPTSPPPDDSLS 715
                +    R+   S      P A  PP      +  SLP SPP   SLS
Sbjct: 425 ATHSFLTMSPRQTQASLTSPSRP-ASTPPDSPPLQAPLSLPASPPLQTSLS 474



 Score = 32.7 bits (73), Expect = 5.0
 Identities = 51/195 (26%), Positives = 65/195 (33%), Gaps = 61/195 (31%)

Query: 2060 SPAVKPPATATPASLPKFNLLLGKVDDGTGR--------EAPKREAPAFPYPTATLAS-- 2109
            +P   PP + +P+S      L G     T            P+  A A P P A LA+  
Sbjct: 877  APGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACH 936

Query: 2110 ------GPQPFLPPGKEATTPTPEPPLPLLPPPPPS---------EEEGPEEP------- 2147
                  GP P L     A    P  PLP  P   P          E EGPE         
Sbjct: 937  PAAWSRGPAPPL-----AFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGAL 991

Query: 2148 -PKASPESEACSLSAGDLSDSSASSLAEP---ESP--------------------GAGGT 2183
             P  SP +     +AG  + +S+ S  +    E P                     A G 
Sbjct: 992  DPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGA 1051

Query: 2184 SGGPGGGTGVPDGMG 2198
            +GG GGG G  +G G
Sbjct: 1052 AGGSGGGPGGAEGGG 1066



 Score = 32.0 bits (71), Expect = 8.5
 Identities = 63/257 (24%), Positives = 87/257 (33%), Gaps = 56/257 (21%)

Query: 2326 APAPEAPPALKAPPATTPA--SMPLGAAPTLPRLAPVLLSGPALAQPPLGNLAPFNSGPA 2383
            A A    PA +AP   TP     P    P  P    VL +  A+ + PL   A       
Sbjct: 10   AGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAG------ 63

Query: 2384 ASSGLLGLATSVLPTTTVVQTAGPGRPLPQRPMPDQTNTSTAGTT--DPVPGPPTEPLGD 2441
                  G+  + +P +     AGP              T +AGT+  +P   PP    G+
Sbjct: 64   ------GIGGATIPESA--PRAGP--------------TRSAGTSSRNPASRPPASGRGE 101

Query: 2442 KVSSERKPVAGPTSSSNDALKNLKALKTTVPALLGGQFLPFPLPP--AGGTAPPAVFGPQ 2499
            +    +    GP SS        +A  TT P  LG + L        A G A  A     
Sbjct: 102  RAPPAKNTSPGPVSSPG------RASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSA 155

Query: 2500 LQGAYFQQLYGMKKGLFPMNPMIPQ-----TLIGL---LPNALLQPPPQPPEPT------ 2545
            L     +   G   G  P   M  +     T +GL    P+A  +PP + P  +      
Sbjct: 156  LSAGARRDTSGPTPGT-PSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 214

Query: 2546 -ATAPPKPPELPAPGEG 2561
             +T  P P     P  G
Sbjct: 215  HSTTEPSPAARRRPSAG 231


>gi|134284361 LIM homeobox protein 6 isoform 2 [Homo sapiens]
          Length = 377

 Score = 68.9 bits (167), Expect = 6e-11
 Identities = 40/112 (35%), Positives = 59/112 (52%), Gaps = 9/112 (8%)

Query: 1964 LKRKHEDGSLSPTGSEAGGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDC 2023
            LKR  E+G+            + +P   KR RT+   EQL+++   + QD+NP  + L  
Sbjct: 221  LKRAAENGNGLTLEGAVPSEQDSQPKPAKRARTSFTAEQLQVMQAQFAQDNNPDAQTLQK 280

Query: 2024 ISEEVGLKKRVVQVWFQNTRARERKGQFRSTPGGVPSPAVKPPATATPASLP 2075
            +++  GL +RV+QVWFQN RAR +K          P   V PP+ A P+ LP
Sbjct: 281  LADMTGLSRRVIQVWFQNCRARHKK--------HTPQHPV-PPSGAPPSRLP 323



 Score = 52.8 bits (125), Expect = 5e-06
 Identities = 25/57 (43%), Positives = 36/57 (63%)

Query: 2200 RRYRTQMSSLQLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKK 2256
            +R RT  ++ QL++M+A +     P  Q  + L +  GL +RVIQVWFQN RA+ KK
Sbjct: 249  KRARTSFTAEQLQVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHKK 305



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 25/72 (34%), Positives = 40/72 (55%)

Query: 1726 PAGRRFSRTKFTEFQTQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKAR 1785
            P   + +RT FT  Q Q +Q+ F     P    +++LA + GL+ RV+ VWFQN R + +
Sbjct: 245  PKPAKRARTSFTAEQLQVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHK 304

Query: 1786 KNACEGGSMPTG 1797
            K+  +    P+G
Sbjct: 305  KHTPQHPVPPSG 316


>gi|134284359 LIM homeobox protein 6 isoform 1 [Homo sapiens]
          Length = 392

 Score = 68.9 bits (167), Expect = 6e-11
 Identities = 40/112 (35%), Positives = 59/112 (52%), Gaps = 9/112 (8%)

Query: 1964 LKRKHEDGSLSPTGSEAGGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDC 2023
            LKR  E+G+            + +P   KR RT+   EQL+++   + QD+NP  + L  
Sbjct: 221  LKRAAENGNGLTLEGAVPSEQDSQPKPAKRARTSFTAEQLQVMQAQFAQDNNPDAQTLQK 280

Query: 2024 ISEEVGLKKRVVQVWFQNTRARERKGQFRSTPGGVPSPAVKPPATATPASLP 2075
            +++  GL +RV+QVWFQN RAR +K          P   V PP+ A P+ LP
Sbjct: 281  LADMTGLSRRVIQVWFQNCRARHKK--------HTPQHPV-PPSGAPPSRLP 323



 Score = 52.8 bits (125), Expect = 5e-06
 Identities = 25/57 (43%), Positives = 36/57 (63%)

Query: 2200 RRYRTQMSSLQLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKK 2256
            +R RT  ++ QL++M+A +     P  Q  + L +  GL +RVIQVWFQN RA+ KK
Sbjct: 249  KRARTSFTAEQLQVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHKK 305



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 25/72 (34%), Positives = 40/72 (55%)

Query: 1726 PAGRRFSRTKFTEFQTQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKAR 1785
            P   + +RT FT  Q Q +Q+ F     P    +++LA + GL+ RV+ VWFQN R + +
Sbjct: 245  PKPAKRARTSFTAEQLQVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHK 304

Query: 1786 KNACEGGSMPTG 1797
            K+  +    P+G
Sbjct: 305  KHTPQHPVPPSG 316


>gi|4505007 LIM homeobox transcription factor 1, beta [Homo sapiens]
          Length = 372

 Score = 68.2 bits (165), Expect = 1e-10
 Identities = 38/108 (35%), Positives = 59/108 (54%), Gaps = 5/108 (4%)

Query: 1946 FGERNPLVAATSPMPGPPLKRKHEDGSLSPT---GSEAGGGGEG--EPPRDKRLRTTILP 2000
            + +   L+++ SP     +K + EDG + P    GS++ G G+   +P R KR RT +  
Sbjct: 146  YEKEKDLLSSVSPDESDSVKSEDEDGDMKPAKGQGSQSKGSGDDGKDPRRPKRPRTILTT 205

Query: 2001 EQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQNTRARERK 2048
            +Q       +   S P RK+ + ++ E GL  RVVQVWFQN RA+ +K
Sbjct: 206  QQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKK 253



 Score = 58.9 bits (141), Expect = 6e-08
 Identities = 39/105 (37%), Positives = 51/105 (48%), Gaps = 1/105 (0%)

Query: 2153 ESEACSLSAGDLSDSSASSLAEPE-SPGAGGTSGGPGGGTGVPDGMGQRRYRTQMSSLQL 2211
            E +  S  + D SDS  S   + +  P  G  S   G G    D    +R RT +++ Q 
Sbjct: 149  EKDLLSSVSPDESDSVKSEDEDGDMKPAKGQGSQSKGSGDDGKDPRRPKRPRTILTTQQR 208

Query: 2212 KIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKK 2256
            +  KA +E    P  +  E L  E GL  RV+QVWFQN RAK KK
Sbjct: 209  RAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKK 253



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 26/56 (46%), Positives = 33/56 (58%)

Query: 1733 RTKFTEFQTQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARKNA 1788
            RT  T  Q +A ++ FE S+ P     E LA+  GL+ RVV VWFQN R K +K A
Sbjct: 200  RTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLA 255


>gi|122937321 UNC homeobox [Homo sapiens]
          Length = 531

 Score = 68.2 bits (165), Expect = 1e-10
 Identities = 117/479 (24%), Positives = 153/479 (31%), Gaps = 122/479 (25%)

Query: 1729 RRFSRTKFTEFQTQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARK-- 1786
            RR +RT FT +Q + L+  F  S YP     E LA  L L    V VWFQN R K RK  
Sbjct: 105  RRRTRTNFTGWQLEELEKAFNESHYPDVFMREALALRLDLVESRVQVWFQNRRAKWRKKE 164

Query: 1787 NACEGGSMPTGGGTGGASGCRRCHATFSCVFELVRHLKKCYDDQTLEEE--EEEAERGEE 1844
            N  +G   P                          H   C  +    EE   +E E+ E+
Sbjct: 165  NTKKGPGRPAHNS----------------------HPTTCSGEPMDPEEIARKELEKMEK 202

Query: 1845 EEEVEEEEVEEEQG--LEPPAG-------------------PEGPLPEPPDGEELSQAEA 1883
            ++   E+++ + QG  L  P G                   PE P P PP  +    A A
Sbjct: 203  KKRKHEKKLLKSQGRHLHSPGGLSLHSAPSSDSDSGGGGLSPEPPEPPPPAAKG-PGAHA 261

Query: 1884 TKAGGKEP--------------------EEKATPSPSPAHTCDQCAISFSSQDLLTS-HR 1922
            + A G  P                       A P P P    D+ A S      + +  R
Sbjct: 262  SGAAGTAPAPPGEPPAPGTCDPAFYPSQRSGAGPQPRPGRPADKDAASCGPGAAVAAVER 321

Query: 1923 RLHFLPSLQPSAPPQLL-DLPLLVFGERNPLVAATSPM---PGPPLKRK----------- 1967
                LP   P +   LL D P       N   AA + +   PG P   +           
Sbjct: 322  GAAGLPKASPFSVESLLSDSPPRRKAASNAAAAAAAGLDFAPGLPCAPRTLIGKGHFLLY 381

Query: 1968 ---HEDGSLSPTGSEAGGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCI 2024
                  G L P  +  GG G    P+D      + P             + P +      
Sbjct: 382  PITQPLGFLVPQAALKGGAGLEPAPKDAPPAPAVPP-------------APPAQASFGAF 428

Query: 2025 SEEVGLKKRVVQVWFQNTRARERKGQFRSTPGGVPSPAVKPPATATPASLPKFNLLLGKV 2084
            S   G                      R +P  V SP    PA A     P  +L     
Sbjct: 429  SGPGGAPDSAFA---------------RRSPDAVASPGAPAPAPA-----PFRDLASAAA 468

Query: 2085 DDGTGREAPK--REAPAFPYPTATLASGPQPFLPPGKEATTPTPEPPLPLLPPPPPSEE 2141
             +G G +        PA P P  +   GP+P  P  + AT   PEP     P PP  EE
Sbjct: 469  TEGGGGDCADAGTAGPAPPPPAPSPRPGPRPPSPAEEPATCGVPEPGAAAGPSPPEGEE 527



 Score = 58.5 bits (140), Expect = 8e-08
 Identities = 95/400 (23%), Positives = 143/400 (35%), Gaps = 51/400 (12%)

Query: 2165 SDSSASSLAEPES--PGAGGTSGGPG-----GGTGVPD----GMGQRRYRTQMSSLQLKI 2213
            S ++A+S+  P    P A G  GG G       +G PD    G  +RR RT  +  QL+ 
Sbjct: 61   SCAAAASVVNPTPLLPAACGV-GGDGQPFKLSDSGDPDKESPGCKRRRTRTNFTGWQLEE 119

Query: 2214 MKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAKLQGTAAGSTGGSSEG 2273
            ++  +     P +   E L   + L +  +QVWFQN RAK +K +      G    +S  
Sbjct: 120  LEKAFNESHYPDVFMREALALRLDLVESRVQVWFQNRRAKWRKKENTKKGPGRPAHNSHP 179

Query: 2274 LLAAQRTDCPYCDVKYDFYVSCRGHLFSRQHLAKLKEAVRAQLKSESKCYDLAPAPEAPP 2333
               +     P                 +R+ L K+++  R   K   K            
Sbjct: 180  TTCSGEPMDP--------------EEIARKELEKMEKKKRKHEKKLLKSQGRHLHSPGGL 225

Query: 2334 ALKAPPATTPASMPLGAAPTLPRLAPVLLSGPALAQPPLGNLAPFNSGPAASSGLLGLAT 2393
            +L + P++   S   G +P  P   P    GP          AP   G   + G      
Sbjct: 226  SLHSAPSSDSDSGGGGLSPEPPEPPPPAAKGPGAHASGAAGTAPAPPGEPPAPGTCD--- 282

Query: 2394 SVLPTTTVVQTAGPGRPLPQRPMPDQTNTSTAGTTDPVPGPPTEPLGDKVSSERKPVAGP 2453
               P     Q +G G   PQ P P +     A +  P         G     +  P +  
Sbjct: 283  ---PAFYPSQRSGAG---PQ-PRPGRPADKDAASCGPGAAVAAVERGAAGLPKASPFSVE 335

Query: 2454 TSSSNDALKNLKALKTTVPALLGGQFLPFPLPPAGGTAPPAVFGPQLQGAYFQQLYGMKK 2513
            +  S+   +   A      A  G  F P  LP     AP  + G   +G +   LY + +
Sbjct: 336  SLLSDSPPRRKAASNAAAAAAAGLDFAP-GLP----CAPRTLIG---KGHFL--LYPITQ 385

Query: 2514 GLFPMNPMIPQTLIGLLPNALLQPPPQPPEPTATAPPKPP 2553
               P+  ++PQ    L   A L+P P+   P    PP PP
Sbjct: 386  ---PLGFLVPQA--ALKGGAGLEPAPKDAPPAPAVPPAPP 420



 Score = 56.6 bits (135), Expect = 3e-07
 Identities = 124/560 (22%), Positives = 189/560 (33%), Gaps = 92/560 (16%)

Query: 1921 HRRLHFLPSLQPSAPPQLLDLPLLVFGERNPLVAATSPMPGPPLKRKHEDGSLSPTGSEA 1980
            H  ++ L   Q  +      +P  + G      AA + +  P          L P     
Sbjct: 30   HHHVYELAGHQLQSAAAAASVPFSIDGLLGGSCAAAASVVNPT--------PLLPAACGV 81

Query: 1981 GGGGE-------GEPPRD------KRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEE 2027
            GG G+       G+P ++      +R RT     QLE L + + +   P   M + ++  
Sbjct: 82   GGDGQPFKLSDSGDPDKESPGCKRRRTRTNFTGWQLEELEKAFNESHYPDVFMREALALR 141

Query: 2028 VGLKKRVVQVWFQNTRARERKGQFRSTPGGVPSPAVKPPATATPASLPKFNLLLGKVDDG 2087
            + L +  VQVWFQN RA+ RK +      G P+    P   +     P         ++ 
Sbjct: 142  LDLVESRVQVWFQNRRAKWRKKENTKKGPGRPAHNSHPTTCSGEPMDP---------EEI 192

Query: 2088 TGREAPKREAPAFPYPTATLASGPQPFLPPGKEATTPTPEPPLPLLPPPPPSEEEG---- 2143
              +E  K E     +    L S  +    PG           L L   P    + G    
Sbjct: 193  ARKELEKMEKKKRKHEKKLLKSQGRHLHSPG----------GLSLHSAPSSDSDSGGGGL 242

Query: 2144 -PEEPPKASPESEACSLSAGDLSDSSASSLAEPESPGAGGTSGGPG--GGTGVPDGMGQR 2200
             PE P    P ++     A   + ++ +   EP +PG    +  P    G G     G+ 
Sbjct: 243  SPEPPEPPPPAAKGPGAHASGAAGTAPAPPGEPPAPGTCDPAFYPSQRSGAGPQPRPGRP 302

Query: 2201 RYRTQMSSLQLKIMKACYEAYRTPTMQECEVLGEEIGLPKR---VIQVWFQNARAKEKKA 2257
              +   S                P      V     GLPK     ++    ++  + K A
Sbjct: 303  ADKDAASC--------------GPGAAVAAVERGAAGLPKASPFSVESLLSDSPPRRKAA 348

Query: 2258 KLQGTAAGSTGGSSEGLLAAQRTDCPYCDVKYDFYVSCRGHLFSRQHLAKLKEAV-RAQL 2316
                 AA +    + GL  A RT            +  +GH         L   V +A L
Sbjct: 349  SNAAAAAAAGLDFAPGLPCAPRT------------LIGKGHFLLYPITQPLGFLVPQAAL 396

Query: 2317 KSESKCYDLAPAP-EAPPALKAPPATTPASMPLGA------AP--TLPRLAPVLLSGPAL 2367
            K  +    L PAP +APPA   PPA  PA    GA      AP     R +P  ++ P  
Sbjct: 397  KGGA---GLEPAPKDAPPAPAVPPA-PPAQASFGAFSGPGGAPDSAFARRSPDAVASPGA 452

Query: 2368 AQPPLGNLAPFNSGPAASSGLLGLATSVLPTTTVVQTAGPGRPLPQRPMPDQTNTSTAGT 2427
              P         S  A   G    A +          A   RP P+ P P +   +T G 
Sbjct: 453  PAPAPAPFRDLASAAATEGGGGDCADAGTAGPAPPPPAPSPRPGPRPPSPAE-EPATCGV 511

Query: 2428 TDP-VPGPPTEPLGDKVSSE 2446
             +P     P+ P G+++  +
Sbjct: 512  PEPGAAAGPSPPEGEELDMD 531



 Score = 33.9 bits (76), Expect = 2.2
 Identities = 63/268 (23%), Positives = 80/268 (29%), Gaps = 44/268 (16%)

Query: 1356 AAIDPSAPARGEAGAPPTTTAATDKPFKCTVCRVSYNQSSTLEIHMRSVLHQTR-SRGTK 1414
            AA  P A A G AG  P        P  C        +S            Q R  R   
Sbjct: 253  AAKGPGAHASGAAGTAPAPPGEPPAPGTCDPAFYPSQRSGAGP--------QPRPGRPAD 304

Query: 1415 TDSKIEGPERSQEEPKEGETEGEVGTEKKGPDTSGFISGLPFLSPPPPPLDLHRFPAPLF 1474
             D+   GP  +    + G      G  K  P +   +  L   SPP      +   A   
Sbjct: 305  KDAASCGPGAAVAAVERGAA----GLPKASPFS---VESLLSDSPPRRKAASNAAAAAAA 357

Query: 1475 TPPVLPPFPLVPESLLKLQQQQLLLPFYLHDLKVGPKLTLAGPAPVLSLPAATPPPPPQP 1534
                 P  P  P +L+  +   LL P       + P+  L G A +   P   PP P  P
Sbjct: 358  GLDFAPGLPCAPRTLIG-KGHFLLYPITQPLGFLVPQAALKGGAGLEPAPKDAPPAPAVP 416

Query: 1535 PKAELAEREWERPPMAKEGNEAGPSSPPD------------------PLPNEAARTAAKA 1576
            P           P  A  G  +GP   PD                  P P      A+ A
Sbjct: 417  PAP---------PAQASFGAFSGPGGAPDSAFARRSPDAVASPGAPAPAPAPFRDLASAA 467

Query: 1577 LLENFGFELVIQYNEGKQAVPPPPTPPP 1604
              E  G +       G    PP P+P P
Sbjct: 468  ATEGGGGDCADAGTAGPAPPPPAPSPRP 495


>gi|33569216 LIM homeobox 9 isoform 1 [Homo sapiens]
          Length = 397

 Score = 68.2 bits (165), Expect = 1e-10
 Identities = 63/202 (31%), Positives = 86/202 (42%), Gaps = 36/202 (17%)

Query: 1904 TCDQCAIS------FSSQDLLTSHRRLHFLPSLQPSAPPQL--LDLPLLVFGERNPLVAA 1955
            TC  C  +      F  +D L  + R HF   LQ   PPQL   +L     G   P    
Sbjct: 160  TCSTCNKTLTTGDHFGMKDSLV-YCRAHFETLLQGEYPPQLSYTELAAKSGGLALPYFNG 218

Query: 1956 TSPMP-GPPLKRK----------HEDGSLSPTGSEAGGGGEGEPP--RDKRLRTTILPEQ 2002
            T  +  G P KRK          +  G             +  PP  + KR+RT+    Q
Sbjct: 219  TGTVQKGRPRKRKSPALGVDIVNYNSGCNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQ 278

Query: 2003 LEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQNTRARERKGQFRSTPGGV---- 2058
            L  +  ++  + NP  K L  ++++ GL KRV+QVWFQN RA+ R+   R   GGV    
Sbjct: 279  LRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNLLRQENGGVDKAD 338

Query: 2059 ----PSP------AVKPPATAT 2070
                P+P      A+ PP TAT
Sbjct: 339  GTSLPAPPSADSGALTPPGTAT 360



 Score = 54.7 bits (130), Expect = 1e-06
 Identities = 30/88 (34%), Positives = 43/88 (48%)

Query: 2194 PDGMGQRRYRTQMSSLQLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAK 2253
            P     +R RT     QL+ MK+ +     P  ++ + L ++ GL KRV+QVWFQNARAK
Sbjct: 262  PPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAK 321

Query: 2254 EKKAKLQGTAAGSTGGSSEGLLAAQRTD 2281
             ++  L+    G        L A    D
Sbjct: 322  FRRNLLRQENGGVDKADGTSLPAPPSAD 349



 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 27/70 (38%), Positives = 39/70 (55%), Gaps = 2/70 (2%)

Query: 1733 RTKFTEFQTQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARKNAC--E 1790
            RT F   Q + ++S+F  +  P   ++++LA   GL  RV+ VWFQNAR K R+N    E
Sbjct: 271  RTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNLLRQE 330

Query: 1791 GGSMPTGGGT 1800
             G +    GT
Sbjct: 331  NGGVDKADGT 340


>gi|62241033 LIM homeobox 9 isoform 2 [Homo sapiens]
          Length = 388

 Score = 68.2 bits (165), Expect = 1e-10
 Identities = 63/202 (31%), Positives = 86/202 (42%), Gaps = 36/202 (17%)

Query: 1904 TCDQCAIS------FSSQDLLTSHRRLHFLPSLQPSAPPQL--LDLPLLVFGERNPLVAA 1955
            TC  C  +      F  +D L  + R HF   LQ   PPQL   +L     G   P    
Sbjct: 151  TCSTCNKTLTTGDHFGMKDSLV-YCRAHFETLLQGEYPPQLSYTELAAKSGGLALPYFNG 209

Query: 1956 TSPMP-GPPLKRK----------HEDGSLSPTGSEAGGGGEGEPP--RDKRLRTTILPEQ 2002
            T  +  G P KRK          +  G             +  PP  + KR+RT+    Q
Sbjct: 210  TGTVQKGRPRKRKSPALGVDIVNYNSGCNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQ 269

Query: 2003 LEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQNTRARERKGQFRSTPGGV---- 2058
            L  +  ++  + NP  K L  ++++ GL KRV+QVWFQN RA+ R+   R   GGV    
Sbjct: 270  LRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNLLRQENGGVDKAD 329

Query: 2059 ----PSP------AVKPPATAT 2070
                P+P      A+ PP TAT
Sbjct: 330  GTSLPAPPSADSGALTPPGTAT 351



 Score = 54.7 bits (130), Expect = 1e-06
 Identities = 30/88 (34%), Positives = 43/88 (48%)

Query: 2194 PDGMGQRRYRTQMSSLQLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAK 2253
            P     +R RT     QL+ MK+ +     P  ++ + L ++ GL KRV+QVWFQNARAK
Sbjct: 253  PPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAK 312

Query: 2254 EKKAKLQGTAAGSTGGSSEGLLAAQRTD 2281
             ++  L+    G        L A    D
Sbjct: 313  FRRNLLRQENGGVDKADGTSLPAPPSAD 340



 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 27/70 (38%), Positives = 39/70 (55%), Gaps = 2/70 (2%)

Query: 1733 RTKFTEFQTQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARKNAC--E 1790
            RT F   Q + ++S+F  +  P   ++++LA   GL  RV+ VWFQNAR K R+N    E
Sbjct: 262  RTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNLLRQE 321

Query: 1791 GGSMPTGGGT 1800
             G +    GT
Sbjct: 322  NGGVDKADGT 331


>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
            1 [Homo sapiens]
          Length = 1250

 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 122/479 (25%), Positives = 159/479 (33%), Gaps = 75/479 (15%)

Query: 1225 NLTPEASPDP-LPEPPLASVEVPDKPSGSPGQPPSPAPSPVPEPDAQAEDVAPPPTMAEE 1283
            +L P  SP P +  P  AS   P  P   P  PP P P P P          PPP +  +
Sbjct: 604  SLVPPLSPQPKIVTPYTASQPSPPLPPPPP-PPPPPPPPPPP----------PPPPLPSQ 652

Query: 1284 EEGTTGELRSAEPAPADSRHPLTYRKTTNFALDKFLDPARPYKCTVCKESFTQKNILLVH 1343
               + G   SA P           +  +  +   F  P  P       +S + K  +LV 
Sbjct: 653  SAPSAG---SAAPMFVKYSTITRLQNASQHSGALFKPPTPP-----VMQSQSVKPQILVP 704

Query: 1344 YNSVSHLHKMKKAAIDPSAPARGEAGAPPTTTAATDKPFKCTVCRVSYNQSST----LEI 1399
             N V          + P  P       PP T  +     K   C  S  Q S     L+I
Sbjct: 705  PNGV----------VPPPPPP-----PPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKI 749

Query: 1400 HMRSVLHQTRSRGTKTDSKIEGPERSQEEPKEGET-EGEVGTEKKGPDTSGFISGLPFLS 1458
            H    + Q           I  P   Q  PK   T      T+   P  +   +  P  +
Sbjct: 750  HQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQ--AAPPTPT 807

Query: 1459 PPPPPLDLH-RFPAPLFTP-PVLPPFPLVPESLLKLQQQQLLLPFYLHDLKVGPKLTLAG 1516
            PP PP      FPA    P P  PP P+ P +L K QQ     P         P   L+ 
Sbjct: 808  PPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPK-QQSFCAKP---------PPSPLSP 857

Query: 1517 PAPVLSLPAATPPPPPQPPKAEL-------AEREWERPPMAKEGNEAGPSSPPDPLPNEA 1569
               V+   A+  PPPP PP  E        A    + PP  K   +  PSS P P P+  
Sbjct: 858  VPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFP 917

Query: 1570 ARTAAKALLENFGFELVIQYNEGKQAVPPPPTPPPPEALGGGDKLACGACGKLFSNMLI- 1628
                  +L         +        VP PP PPPP A    DK   G+ GK  S     
Sbjct: 918  PPPPESSL---------VFPPPPPSPVPAPPPPPPPTASPTPDK--SGSPGKKTSKTSSP 966

Query: 1629 --LKTHEEHVHRRFLPFEALSRYAAQFRKSYDSLYPPLAEPPKPPDGSLDSPVPHLGPP 1685
               K          +   + + +    R S DSL      P +    S ++  P   PP
Sbjct: 967  GGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPP 1025



 Score = 58.9 bits (141), Expect = 6e-08
 Identities = 66/262 (25%), Positives = 90/262 (34%), Gaps = 37/262 (14%)

Query: 2325 LAPAPEAPPALKAPPATTPASMPLGAAPTLPRLAP------------VLLSGPALAQPPL 2372
            + P P  PP    P +      P   AP+LP+ +             +    P    PP 
Sbjct: 708  VVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPP 767

Query: 2373 GNLAPFN-SGPAASSGLLGLATSVLPTTTVVQTAGPGRPLPQRPMPDQTNTSTAGTTDPV 2431
               AP     P      +   TS      VV  A P  P P  P+P          +   
Sbjct: 768  PIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTP--PVPPAKKQPAFPASYIP 825

Query: 2432 PGPPTEPLGDKVSSERKPVAGPTSSSNDAL--KNLKALKTTVPAL---LGGQFLPFPLPP 2486
            P PPT P+         PV  PT     +   K   +  + VP++   +  QF P P PP
Sbjct: 826  PSPPTPPV---------PVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPP 876

Query: 2487 AGGTAP----PAVFGPQLQGAYFQQLYGMKKGLFPMNPMIPQTLIGLLPNALLQPPPQPP 2542
            A  + P    PA   PQ   A   +       +   +P  P       P + L  PP PP
Sbjct: 877  AMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPP----PESSLVFPPPPP 932

Query: 2543 EPTATAPPKPPELPAPGEGEAG 2564
             P    PP PP   +P   ++G
Sbjct: 933  SPVPAPPPPPPPTASPTPDKSG 954



 Score = 45.4 bits (106), Expect = 7e-04
 Identities = 62/254 (24%), Positives = 89/254 (35%), Gaps = 44/254 (17%)

Query: 2325 LAPAPEAPPALKAPPATTPASMPLGAAPTLPRLAPVLLSGPALAQPPLGNLAPFNSGPAA 2384
            + P+P  PP +  PP T P      A P    L+PV    P++ +       P  + PA 
Sbjct: 824  IPPSPPTPP-VPVPPPTLPKQQSFCAKPPPSPLSPV----PSVVKQIASQFPPPPTPPAM 878

Query: 2385 SSG-LLGLATSVLPTTTVVQTAGP-----GRPLPQR----PMPDQTNTSTAGTTDPVPGP 2434
             S  L  +  +V P +     A P       P+P      P P+ +         PVP P
Sbjct: 879  ESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAP 938

Query: 2435 PTEPLGDKVSSERKPVAGPTSSSNDALKNLKALKTTVPALLGGQFLPFPLPPAGGTAPPA 2494
            P  P          P A PT   + +    K  KT+ P               GG  PP 
Sbjct: 939  PPPP---------PPTASPTPDKSGS-PGKKTSKTSSP---------------GGKKPPP 973

Query: 2495 VFGPQLQGAYFQQLYGMKKGLFPMNPMIPQTLIGLLPNALLQPPPQPPEPTATAPPKPPE 2554
               PQ + +  +   G +    P  P +   +    P A    P +   P   APPKP +
Sbjct: 974  T--PQ-RNSSIKSSSGAEHPE-PKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGK 1029

Query: 2555 LPAPGEGEAGEVDE 2568
            L   G    G + +
Sbjct: 1030 LNLSGVNLPGVLQQ 1043



 Score = 45.4 bits (106), Expect = 7e-04
 Identities = 30/103 (29%), Positives = 47/103 (45%), Gaps = 4/103 (3%)

Query: 1224 PNLTPEASPDPLPEPPLAS-VEVPDKPSGSPGQPPSPAPSPVPEPD---AQAEDVAPPPT 1279
            P+  P  SPD  P PP +S V  P  PS  P  PP P P+  P PD   +  +  +   +
Sbjct: 906  PSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSS 965

Query: 1280 MAEEEEGTTGELRSAEPAPADSRHPLTYRKTTNFALDKFLDPA 1322
               ++   T +  S+  + + + HP   R + +  + KF  PA
Sbjct: 966  PGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPA 1008



 Score = 45.1 bits (105), Expect = 0.001
 Identities = 68/279 (24%), Positives = 106/279 (37%), Gaps = 41/279 (14%)

Query: 2328 APEAPPALKAPPATTPASMPLGAAPTLPRLAPVLLSGPALAQPPLGNLAPFNSGPAASSG 2387
            AP++PPA+KA P   P+S+P+  +P  P   P       +  PP  +  P    P   + 
Sbjct: 891  APQSPPAVKAKPKWQPSSIPV-PSPDFPPPPP---ESSLVFPPPPPSPVPAPPPPPPPTA 946

Query: 2388 LLGLATSVLPTTTVVQTAGPGRPLPQRPMPDQTNTSTAGTTDPVPGPPTEPLGDKVSSER 2447
                  S  P     +T+ PG   P  P   Q N+S   ++      P  P  D + S+ 
Sbjct: 947  SPTPDKSGSPGKKTSKTSSPGGKKP--PPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKF 1004

Query: 2448 KPVAGPTSSSNDALKNLKALKTTVPALLGGQFLPFPLPPAGGTAPPAVFGPQLQGAYFQQ 2507
             P A   S S          K T+P            PPA   APP      L G     
Sbjct: 1005 TPPAESGSPS----------KETLP------------PPA---APPKPGKLNLSGVNLPG 1039

Query: 2508 LYGMKKGLFPMNPMIPQTLIGLLPNALLQPPPQPPEPTATAPPKPPELPAPGEGEAGEVD 2567
            +  +++G       +   L G   +++++ P  P +     PP   ELP P      E+ 
Sbjct: 1040 V--LQQGCVSAKAPV---LSGRGKDSVVEFPSPPSDSDFPPPPPETELPLP----PIEIP 1090

Query: 2568 ELLTGSTGISTVDVTHRYLCRQCKMAFDGEAPATAHQRS 2606
             + +G+T    V V +    +  KM+     P T  +R+
Sbjct: 1091 AVFSGNTS-PKVAVVNPQPQQWSKMSVKKAPPPTRPKRN 1128



 Score = 42.7 bits (99), Expect = 0.005
 Identities = 84/380 (22%), Positives = 125/380 (32%), Gaps = 77/380 (20%)

Query: 1844 EEEEVEEEEVEEEQGLEPPAGPEGPLPEPPDGEELSQAEATKAGGKEPEEKATPSPSPAH 1903
            + + V+ + +    G+ PP  P  P P P  G  ++Q +        P+  A P P   H
Sbjct: 693  QSQSVKPQILVPPNGVVPPPPP--PPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIH 750

Query: 1904 TCDQCAISFSSQDLLTSHRRLHFLPS-LQPSAPPQ-LLDLPLLVFGER-NPLVA-ATSPM 1959
                  +   +Q    +      +P+ L P APP+ L+ +P     +   P+V  A  P 
Sbjct: 751  Q-----VQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPT 805

Query: 1960 PGPPLKRKHEDGSLSPTGSEAGGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRK 2019
            P PP+          P   +        PP        + P  L        Q S   + 
Sbjct: 806  PTPPVP---------PAKKQPAFPASYIPPSPPTPPVPVPPPTLP------KQQSFCAKP 850

Query: 2020 MLDCISEEVGLKKRVVQVWFQNTRARERKGQFRS--TPGGVPSPAVKP-PATATPASLPK 2076
                +S    + K++               QF    TP  + S  +KP PA   P S P 
Sbjct: 851  PPSPLSPVPSVVKQIAS-------------QFPPPPTPPAMESQPLKPVPANVAPQSPPA 897

Query: 2077 FNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQPFLPPGKEATTPTPEPPLPLLPPP 2136
                         +  PK +  + P P+        P  PP      P PE  L   PPP
Sbjct: 898  V------------KAKPKWQPSSIPVPS--------PDFPP------PPPESSLVFPPPP 931

Query: 2137 P-PSEEEGPEEPPKASPESEACSLSAGDLSDSSASSLAEPESPGAGGTSGGPGGGTGVPD 2195
            P P     P  PP ASP          D S S     ++  SPG       P   + +  
Sbjct: 932  PSPVPAPPPPPPPTASP--------TPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKS 983

Query: 2196 GMGQRRYRTQMSSLQLKIMK 2215
              G      +  S+   + K
Sbjct: 984  SSGAEHPEPKRPSVDSLVSK 1003



 Score = 41.6 bits (96), Expect = 0.011
 Identities = 86/370 (23%), Positives = 122/370 (32%), Gaps = 66/370 (17%)

Query: 1224 PNLTPEASPDPLPEPPLASVEVPDKPSGSPGQPPSPAPSPVPE---PDAQAEDVAPPPTM 1280
            P +T  A P P P  P A  +     S  P  PP+P P PVP    P  Q+    PPP+ 
Sbjct: 796  PVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTP-PVPVPPPTLPKQQSFCAKPPPSP 854

Query: 1281 AEEEEGTTGELRSAEPAPADSRHPLTYRKTTNFALDKFLDPARPYKCTVCKES------- 1333
                     ++ S  P P            T  A++    P +P    V  +S       
Sbjct: 855  LSPVPSVVKQIASQFPPP-----------PTPPAMES--QPLKPVPANVAPQSPPAVKAK 901

Query: 1334 -FTQKNILLVHYNSVSHLHKMKKAAIDPSAPARGEAGAPPTTTAATDKPFKCTVCRVSYN 1392
               Q + + V                 P  P+   A  PP    A+  P K      S  
Sbjct: 902  PKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSG----SPG 957

Query: 1393 QSSTLEIHMRSVLHQTRSRGTKTDSKIEGPERSQEEPKEGETEGEVGTEKKGPDTSGFIS 1452
            + ++          +T S G K     + P   Q       + G    E K P     +S
Sbjct: 958  KKTS----------KTSSPGGK-----KPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVS 1002

Query: 1453 GLPFLSPPPPPLDLHRFPAPLFTPPVLPPFPLVPESLLKLQQQQLLLPFYLHDLKV---G 1509
                     PP +          PP  PP P       KL    + LP  L    V    
Sbjct: 1003 KF------TPPAESGSPSKETLPPPAAPPKP------GKLNLSGVNLPGVLQQGCVSAKA 1050

Query: 1510 PKLTLAGPAPVLSLPAATPPP----PPQPPKAELAEREWERPPMAKEGNEAGPSSPPDPL 1565
            P L+  G   V+  P  +PP     PP PP+ EL     E P +   GN +   +  +P 
Sbjct: 1051 PVLSGRGKDSVVEFP--SPPSDSDFPPPPPETELPLPPIEIPAVF-SGNTSPKVAVVNPQ 1107

Query: 1566 PNEAARTAAK 1575
            P + ++ + K
Sbjct: 1108 PQQWSKMSVK 1117



 Score = 38.9 bits (89), Expect = 0.070
 Identities = 20/61 (32%), Positives = 27/61 (44%)

Query: 2101 PYPTATLASGPQPFLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESEACSLS 2160
            PY +      PQP +     A+ P+P  P P  PPPPP     P  PP  S  + +   +
Sbjct: 601  PYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSA 660

Query: 2161 A 2161
            A
Sbjct: 661  A 661



 Score = 37.7 bits (86), Expect = 0.15
 Identities = 23/58 (39%), Positives = 25/58 (43%), Gaps = 6/58 (10%)

Query: 2098 PAFPYP---TATLASGPQPFLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPKASP 2152
            P  P P   T   AS P P LPP      P P PP P  PPPPP   +       A+P
Sbjct: 608  PLSPQPKIVTPYTASQPSPPLPP---PPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAP 662



 Score = 35.4 bits (80), Expect = 0.77
 Identities = 14/28 (50%), Positives = 15/28 (53%)

Query: 2537 PPPQPPEPTATAPPKPPELPAPGEGEAG 2564
            PPP PP P    PP PP LP+     AG
Sbjct: 631  PPPPPPPPPPPPPPPPPPLPSQSAPSAG 658



 Score = 33.1 bits (74), Expect = 3.8
 Identities = 18/40 (45%), Positives = 20/40 (50%), Gaps = 2/40 (5%)

Query: 2520 PMIPQTLIGLLPNALLQP-PPQPPEPTATAPPKPPELPAP 2558
            P+ PQ  I + P    QP PP PP P    PP PP  P P
Sbjct: 608  PLSPQPKI-VTPYTASQPSPPLPPPPPPPPPPPPPPPPPP 646



 Score = 33.1 bits (74), Expect = 3.8
 Identities = 12/24 (50%), Positives = 13/24 (54%)

Query: 2537 PPPQPPEPTATAPPKPPELPAPGE 2560
            PPP PP P    PP PP  P P +
Sbjct: 629  PPPPPPPPPPPPPPPPPPPPLPSQ 652



 Score = 33.1 bits (74), Expect = 3.8
 Identities = 28/100 (28%), Positives = 34/100 (34%), Gaps = 13/100 (13%)

Query: 345 PPSPPTATWDPSPTQAKESPVAAGEAGPDW--------FPEGQEEDGGL----CPPLNQS 392
           PP PP     P P    +S  +AG A P +             +  G L     PP+ QS
Sbjct: 635 PPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQS 694

Query: 393 SPTSKEGGTLP-APVGSPEDPSDPPQPYRLADDYTPAPAA 431
                +    P   V  P  P  PP P        PAP A
Sbjct: 695 QSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCA 734



 Score = 33.1 bits (74), Expect = 3.8
 Identities = 33/137 (24%), Positives = 47/137 (34%), Gaps = 22/137 (16%)

Query: 2055 PGGVPSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQPF 2114
            P  VP+P   PP TA+P                 G++  K  +P    P  T    PQ  
Sbjct: 932  PSPVPAPPPPPPPTASPTP---------DKSGSPGKKTSKTSSPGGKKPPPT----PQRN 978

Query: 2115 LPPGKEATTPTPEPPLPLLPP-----PPPSEEEGPEE----PPKASPESEACSLSAGDLS 2165
                  +    PEP  P +        PP+E   P +    PP A P+    +LS  +L 
Sbjct: 979  SSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLP 1038

Query: 2166 DSSASSLAEPESPGAGG 2182
                      ++P   G
Sbjct: 1039 GVLQQGCVSAKAPVLSG 1055



 Score = 32.7 bits (73), Expect = 5.0
 Identities = 33/118 (27%), Positives = 40/118 (33%), Gaps = 13/118 (11%)

Query: 610 PGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRP-DKPLEAQLLLNGFH 668
           P L  P PPPPP   P  PP       P  L     P AG       K      L N   
Sbjct: 626 PPLPPPPPPPPPPPPPPPPP-------PPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQ 678

Query: 669 HVGAPAR--KFPTSAPGSLSPDAHLPPSQLLGSSSDSLPTSPPPDDSLSLKVFRCLVC 724
           H GA  +    P     S+ P   +PP+   G      P  PPP    ++   +   C
Sbjct: 679 HSGALFKPPTPPVMQSQSVKPQILVPPN---GVVPPPPPPPPPPTPGSAMAQLKPAPC 733



 Score = 32.3 bits (72), Expect = 6.5
 Identities = 32/104 (30%), Positives = 38/104 (36%), Gaps = 31/104 (29%)

Query: 617  PPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRPDKPLEAQLLLNGFHHVGAPARK 676
            PPPPP   P  PP             P  P A P   PDK              G+P +K
Sbjct: 928  PPPPPSPVPAPPP-------------PPPPTASP--TPDKS-------------GSPGKK 959

Query: 677  -FPTSAPGSLSPDAHLPPSQLLGSSSDSLPTSP--PPDDSLSLK 717
               TS+PG   P      +  + SSS +    P  P  DSL  K
Sbjct: 960  TSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSK 1003



 Score = 32.0 bits (71), Expect = 8.5
 Identities = 28/93 (30%), Positives = 36/93 (38%), Gaps = 18/93 (19%)

Query: 609 PPGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGL----RPDKPLEAQLLL 664
           P G++ P PPPPP  TP S           A+ Q +     P L     P  PL+   + 
Sbjct: 705 PNGVVPPPPPPPPPPTPGS-----------AMAQLKPAPCAPSLPQFSAPPPPLKIHQVQ 753

Query: 665 NGFHHVGAPARKFPTSAPGSLSPDAHLPPSQLL 697
           +    V  P    P   P  L P A  PP  L+
Sbjct: 754 H-ITQVAPPTPPPPPPIPAPLPPQA--PPKPLV 783



 Score = 32.0 bits (71), Expect = 8.5
 Identities = 36/137 (26%), Positives = 46/137 (33%), Gaps = 27/137 (19%)

Query: 345  PPSPPTATWDPSPTQAKESPVAAGEAGPDWFPEGQEEDGGLCP---PLNQSSPTSKEGG- 400
            PPSP  A   P P  A  +P  +G  G           GG  P   P   SS  S  G  
Sbjct: 931  PPSPVPAPPPPPPPTASPTPDKSGSPGKK--TSKTSSPGGKKPPPTPQRNSSIKSSSGAE 988

Query: 401  ----------------TLPAPVGSPE-----DPSDPPQPYRLADDYTPAPAAFQGLSLSS 439
                            T PA  GSP       P+ PP+P +L       P   Q   +S+
Sbjct: 989  HPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSA 1048

Query: 440  HMSLLHSRNSCKTLKCP 456
               +L  R     ++ P
Sbjct: 1049 KAPVLSGRGKDSVVEFP 1065


>gi|12707580 paired-like homeobox 2b [Homo sapiens]
          Length = 314

 Score = 66.2 bits (160), Expect = 4e-10
 Identities = 68/230 (29%), Positives = 101/230 (43%), Gaps = 22/230 (9%)

Query: 1983 GGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQNT 2042
            GG  E  + +R+RTT    QL+ L R + +   P     + ++ ++ L +  VQVWFQN 
Sbjct: 90   GGLNEKRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNR 149

Query: 2043 RARERKGQFRSTPGGVPSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAFPY 2102
            RA+ RK               +  A A  A+  K N   GK  D + R+   +EA +   
Sbjct: 150  RAKFRK---------------QERAAAAAAAAAK-NGSSGKKSD-SSRDDESKEAKSTD- 191

Query: 2103 PTATLASGPQPFLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPK--ASPESEACSLS 2160
            P +T   GP P   P   A       P P   P          EP K  A+  + A + +
Sbjct: 192  PDSTGGPGPNPNPTPSCGANGGGGGGPSPAGAPGAAGPGGPGGEPGKGGAAAAAAAAAAA 251

Query: 2161 AGDLSDSSASSLAEPESPGAGGTSGGPGGGTGVPDGMGQRRYRTQMSSLQ 2210
            A   + ++A  LA    PG  G + GPG  T +PD +G   + + +SSLQ
Sbjct: 252  AAAAAAAAAGGLAAAGGPGQ-GWAPGPGPITSIPDSLG-GPFASVLSSLQ 299



 Score = 48.5 bits (114), Expect = 9e-05
 Identities = 31/87 (35%), Positives = 45/87 (51%), Gaps = 6/87 (6%)

Query: 2192 GVPDGMGQRRYRTQMSSLQLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNAR 2251
            G+ +   QRR RT  +S QLK ++  +     P +   E L  +I L +  +QVWFQN R
Sbjct: 91   GLNEKRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRR 150

Query: 2252 AKEKKAKLQGTAA------GSTGGSSE 2272
            AK +K +    AA      GS+G  S+
Sbjct: 151  AKFRKQERAAAAAAAAAKNGSSGKKSD 177



 Score = 41.6 bits (96), Expect = 0.011
 Identities = 29/83 (34%), Positives = 36/83 (43%), Gaps = 3/83 (3%)

Query: 1729 RRFSRTKFTEFQTQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARKN- 1787
            +R  RT FT  Q + L+  F  + YP     E LA  + L    V VWFQN R K RK  
Sbjct: 98   QRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFRKQE 157

Query: 1788 --ACEGGSMPTGGGTGGASGCRR 1808
              A    +    G +G  S   R
Sbjct: 158  RAAAAAAAAAKNGSSGKKSDSSR 180


>gi|169881277 PROP paired-like homeobox 1 [Homo sapiens]
          Length = 226

 Score = 65.9 bits (159), Expect = 5e-10
 Identities = 60/206 (29%), Positives = 86/206 (41%), Gaps = 10/206 (4%)

Query: 2152 PESEACSLSAGDLSDSSASSLAEPESPGAGGTSGGPGGGT-GVPDGMGQRRYRTQMSSLQ 2210
            PE    + +     DSSA         G G +   P GG  G P    +RR+RT  S +Q
Sbjct: 23   PERHPATGTPTTTVDSSAPPCRRLPGAGGGRSRFSPQGGQRGRPHS--RRRHRTTFSPVQ 80

Query: 2211 LKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAK---LQGTAAGST 2267
            L+ +++ +   + P +   E L  + GL +  IQVWFQN RAK++K +   LQ  A  S 
Sbjct: 81   LEQLESAFGRNQYPDIWARESLARDTGLSEARIQVWFQNRRAKQRKQERSLLQPLAHLSP 140

Query: 2268 GGSSEGLLAAQRTDCPYCDVKYDFYVSCRGHLFSRQHLAKLKEAVRAQLKSESKCYDLAP 2327
               S  L   + T CPY        V+C  H +S  H    + +         +  D  P
Sbjct: 141  AAFSSFL--PESTACPYSYAAPPPPVTCFPHPYS--HALPSQPSTGGAFALSHQSEDWYP 196

Query: 2328 APEAPPALKAPPATTPASMPLGAAPT 2353
                 PA   P    P  +PL   P+
Sbjct: 197  TLHPAPAGHLPCPPPPPMLPLSLEPS 222



 Score = 60.1 bits (144), Expect = 3e-08
 Identities = 62/206 (30%), Positives = 83/206 (40%), Gaps = 32/206 (15%)

Query: 1948 ERNPLVAA---TSPMPGPPLKRKHEDGSLSPTGSEAGGGGEGEPPRDKRLRTTILPEQLE 2004
            ER+P       T     PP +R    G      S  GG   G P   +R RTT  P QLE
Sbjct: 24   ERHPATGTPTTTVDSSAPPCRRLPGAGGGRSRFSPQGGQ-RGRPHSRRRHRTTFSPVQLE 82

Query: 2005 ILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQNTRARERKGQFRSTPGGVPSPAVK 2064
             L   + ++  P     + ++ + GL +  +QVWFQN RA++RK Q RS         ++
Sbjct: 83   QLESAFGRNQYPDIWARESLARDTGLSEARIQVWFQNRRAKQRK-QERS--------LLQ 133

Query: 2065 PPATATPASLPKFNLLLGKVDDGTGREAPKREAPAFPYP-TATLASGPQ----------- 2112
            P A  +PA+   F  L           AP      FP+P +  L S P            
Sbjct: 134  PLAHLSPAAFSSF--LPESTACPYSYAAPPPPVTCFPHPYSHALPSQPSTGGAFALSHQS 191

Query: 2113 ----PFLPPGKEATTPTPEPPLPLLP 2134
                P L P      P P PP P+LP
Sbjct: 192  EDWYPTLHPAPAGHLPCPPPP-PMLP 216



 Score = 48.5 bits (114), Expect = 9e-05
 Identities = 39/121 (32%), Positives = 49/121 (40%), Gaps = 8/121 (6%)

Query: 1669 KPPDGSLDSPV-PHLGPPFLVPEPEAGGTRAPEER--SRAGGHWPIEEEESSRGNLPPLV 1725
            KP  G + S + P   P    P      +  P  R     GG      +   RG      
Sbjct: 11   KPKKGRVGSNLLPERHPATGTPTTTVDSSAPPCRRLPGAGGGRSRFSPQGGQRGR----- 65

Query: 1726 PAGRRFSRTKFTEFQTQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKAR 1785
            P  RR  RT F+  Q + L+S F  + YP     E LA   GL+   + VWFQN R K R
Sbjct: 66   PHSRRRHRTTFSPVQLEQLESAFGRNQYPDIWARESLARDTGLSEARIQVWFQNRRAKQR 125

Query: 1786 K 1786
            K
Sbjct: 126  K 126


>gi|156416026 zinc finger protein 219 [Homo sapiens]
          Length = 722

 Score = 65.5 bits (158), Expect = 7e-10
 Identities = 107/431 (24%), Positives = 147/431 (34%), Gaps = 105/431 (24%)

Query: 1517 PAPVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPSSPPDPLPNEAARTAAKA 1576
            P   L+  +A PPP PQP           +PP   E     P S P P P          
Sbjct: 215  PERPLAATSAAPPPQPQP-----------QPPPQPE-----PRSVPQPEPEP-------- 250

Query: 1577 LLENFGFELVIQYNEGKQAVPPPPTPPPPEALGGGDKLACGACGKLFSNMLILKTHEEHV 1636
                          E ++   P P P  PE      +  C  CG+ F+    LK H    
Sbjct: 251  --------------EPEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKH 296

Query: 1637 HRRF---LPFEALSRYAAQFRKSYDSLYP----PLAEP---------PKPPDGSLDSPVP 1680
               F    P          F K++  ++     PL  P         P+PPD  L +  P
Sbjct: 297  KASFDHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAPGPASGPARAPQPPDLGLLAYEP 356

Query: 1681 HLGPPFLV-PEPEAGGTRAPEE-----RSRAGGHWPIEEEES-----SRGNLPPL---VP 1726
             LGP  L+ P P     R P         RAG   P  E        S G   PL   +P
Sbjct: 357  -LGPALLLAPAPTPAERREPPSLLGYLSLRAGEGRPNGEGAEPGPGRSFGGFRPLSSALP 415

Query: 1727 AGRRFSRTKFTEFQTQALQSFFET-----------SAYPKDGE-VERLASLLGLASRVVV 1774
            A  R  R +  E + + +++  ET           S +P+ GE     AS  G  +R   
Sbjct: 416  ARARRHRAEEPEEEEEVVEAEEETWARGRSLGSLASLHPRPGEGPGHSASAAGAQARSTA 475

Query: 1775 VWFQNARQKARKNACEGGSMPTGGGTGGASGCRRCHATFSCVFELVRHLKKCYDDQTLE- 1833
               +N           GG+ P GG       C  C  +F     L  HL+    ++  + 
Sbjct: 476  TQEEN-------GLLVGGTRPEGGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKC 528

Query: 1834 --EEEEEAERGEEEEEVEEEEVEEEQGLEPPAGPEGPLPEPPDGEELSQAEATKAGGKEP 1891
               +    + G  +  ++    E+  G    AGP GP PEPP   +          G  P
Sbjct: 529  PHCDYAGTQSGSLKYHLQRHHREQRSG----AGP-GPPPEPPPPSQ---------RGSAP 574

Query: 1892 EEKATPSPSPA 1902
            +  A PSP PA
Sbjct: 575  QSGAKPSPQPA 585



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 114/487 (23%), Positives = 158/487 (32%), Gaps = 114/487 (23%)

Query: 1236 PEPPLASVEVPDKPSGSPGQPPSPAPSPVPEPDAQAEDVAPPPTMAEEEEGTTGELRSAE 1295
            PE PLA+      P   P  PP P P  VP+P+ + E          E E T        
Sbjct: 215  PERPLAATSAAPPPQPQPQPPPQPEPRSVPQPEPEPE---------PEREAT------PT 259

Query: 1296 PAPADSRHPLTYRKTTNFALDKFLDPARP-YKCTVCKESFTQKNILLVHYNSVSHLHKMK 1354
            PAPA    P                PA P ++C VC +SFTQ   L  H        +  
Sbjct: 260  PAPAAPEEP----------------PAPPEFRCQVCGQSFTQSWFLKGHM-------RKH 296

Query: 1355 KAAIDPSAPARGEAGAPPTTTAATDKPFKCTVCRVSYNQSSTLEIHMRSVLHQTRSRGTK 1414
            KA+ D +                      C VC   + +   L+ HM+  +H ++    +
Sbjct: 297  KASFDHA----------------------CPVCGRCFKEPWFLKNHMK--VHASKLGPLR 332

Query: 1415 TDSKIEGPERSQEEPKEGETEGEVGTEKKGPDTSGFISGLPFLSPPPPPLDLHRFPAPLF 1474
                  GP R+ + P      G +  E  GP           L+P P P +  R P  L 
Sbjct: 333  APGPASGPARAPQPP----DLGLLAYEPLGPAL--------LLAPAPTPAE-RREPPSLL 379

Query: 1475 TPPVLPPFPLVPESLLKLQQQQLLLPFYLHDLKVGPKLTLAGPAPVLS-LPAATPPPPPQ 1533
                L      P                    + GP  +  G  P+ S LPA       +
Sbjct: 380  GYLSLRAGEGRPNG---------------EGAEPGPGRSFGGFRPLSSALPARARRHRAE 424

Query: 1534 PPKAELAEREWERPPMAKEGNEAGPSSPPDPLPNEAARTAAKALLENFGFELVIQYNEGK 1593
             P+ E    E E    A+ G   G  +   P P E    +A A     G +      + +
Sbjct: 425  EPEEEEEVVEAEEETWAR-GRSLGSLASLHPRPGEGPGHSASAA----GAQARSTATQEE 479

Query: 1594 QAVPPPPTPPPPEALGGGDKLACGACGKLFSNMLILKTHEEHVHRRFLPFE--------- 1644
              +    T   PE   G     C  CGK F +   LK H   VH    P++         
Sbjct: 480  NGLLVGGT--RPEGGRGATGKDCPFCGKSFRSAHHLKVH-LRVHTGERPYKCPHCDYAGT 536

Query: 1645 ---ALSRYAAQFRKSYDSLYPPLAEPPKPPDGSLDSPVPHLG-PPFLVPEPEAGGTRAPE 1700
               +L  +  +  +   S   P   PP+PP  S     P  G  P   P     G  +P 
Sbjct: 537  QSGSLKYHLQRHHREQRSGAGP-GPPPEPPPPSQRGSAPQSGAKPSPQPATWVEGASSPR 595

Query: 1701 ERSRAGG 1707
              S   G
Sbjct: 596  PPSSGAG 602



 Score = 52.4 bits (124), Expect = 6e-06
 Identities = 111/510 (21%), Positives = 156/510 (30%), Gaps = 122/510 (23%)

Query: 1788 ACEGGSMPTGGGTGGASGCRRCHATFSCVFELVRHLK------KCYDDQTLEEEEEEAER 1841
            A EG + P    +  A  C  C   F    E  RHL       KC        +EEE   
Sbjct: 148  ATEGLARPQAPSSS-AFRCPYCKGKFRTSAERERHLHILHRPWKCGLCSFGSSQEEELLH 206

Query: 1842 GEEEEEVEEEEVEEEQGLEPPAGPEGPLPEPPDGEELSQAEATKAGGKEPEEKATPSPSP 1901
                     E         PP  P+   P  P+   + Q E       EPE +ATP+P+P
Sbjct: 207  HSLTAHGAPERPLAATSAAPPPQPQPQPPPQPEPRSVPQPEPEP----EPEREATPTPAP 262

Query: 1902 A--------------------------------------HTCDQCAISFSSQDLLTSHRR 1923
            A                                      H C  C   F     L +H +
Sbjct: 263  AAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMK 322

Query: 1924 LHFL---------PSLQPSAPPQLLDLPLLVFGERNP-LVAATSPMPGPPLKRKHEDGSL 1973
            +H           P+  P+  PQ  DL LL +    P L+ A +P P    +     G L
Sbjct: 323  VHASKLGPLRAPGPASGPARAPQPPDLGLLAYEPLGPALLLAPAPTPAERREPPSLLGYL 382

Query: 1974 SPTGSEAGGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKR 2033
            S    E    GEG  P   R      P    +        +   R   +   EE  + + 
Sbjct: 383  SLRAGEGRPNGEGAEPGPGRSFGGFRPLSSAL-------PARARRHRAEEPEEEEEVVEA 435

Query: 2034 VVQVWFQNTRARERKGQFRSTPGGVP--SPAVKPPATATPASLPKFNLLLGKVDDGTGRE 2091
              + W +  R+          PG  P  S +       + A+  +  LL+G      GR 
Sbjct: 436  EEETWARG-RSLGSLASLHPRPGEGPGHSASAAGAQARSTATQEENGLLVGGTRPEGGRG 494

Query: 2092 APKREAP--AFPYPTA-------TLASGPQPFLPP----------------------GKE 2120
            A  ++ P     + +A        + +G +P+  P                       + 
Sbjct: 495  ATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRS 554

Query: 2121 ATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPES----EACSLSAGDLSDSSASSLAEPE 2176
               P P P     PPPP      P+   K SP+     E  S      S +   S  +P 
Sbjct: 555  GAGPGPPPE----PPPPSQRGSAPQSGAKPSPQPATWVEGASSPRPPSSGAGPGSRRKPA 610

Query: 2177 SP------GAGGTS--------GGPGGGTG 2192
            SP      G GG +         GPGG  G
Sbjct: 611  SPGRTLRNGRGGEAEPLDLSLRAGPGGEAG 640



 Score = 46.6 bits (109), Expect = 3e-04
 Identities = 99/420 (23%), Positives = 145/420 (34%), Gaps = 80/420 (19%)

Query: 398 EGGTLPAPVGSPEDPSDPPQPYRL-ADDYTPAPAAFQGLSLSSHMSLLHSRNSCKTLKCP 456
           EG    AP G    PS P     L    Y+  PA   G      +S   SR   +   CP
Sbjct: 2   EGSRPRAPSGHLA-PSPPAFDGELDLQRYSNGPAVSAGSLGMGAVSWSESRAGERRFPCP 60

Query: 457 KCNWHYKYQQTLDVHMREKHPESNS-HCSYCSAGGAHPRLARGESYNCGYKPYRCDVCNY 515
            C   +++   L +H+R  HP + +  C +C    A   L R  S+   ++P R      
Sbjct: 61  VCGKRFRFNSILALHLR-AHPGAQAFQCPHCGHRAAQRALLR--SHLRTHQPER----PR 113

Query: 516 STTTKGNLSIHMQSDKHLANLQGFQAGPGGQGSPPEASLPPSAGDKEPKTKSSWQCKVC- 574
           S   +  L +  ++    A L   ++  G Q +P    L       +  + S+++C  C 
Sbjct: 114 SPAARLLLELEERALLREARLGRARSSGGMQATPATEGL----ARPQAPSSSAFRCPYCK 169

Query: 575 -SYETNISRNLRIHMTSEKHMQNVLMLHQGLPLGLPPGLMGPGPPPPPGATPTSPPELFQ 633
             + T+  R   +H           +LH+    GL              +  +S  E   
Sbjct: 170 GKFRTSAERERHLH-----------ILHRPWKCGL-------------CSFGSSQEEELL 205

Query: 634 YFGPQALGQPQTPLAGPGLRPDKPLEAQLLLNGFHHVGAPARKFPTSAPGSLSPDAHLPP 693
           +    A G P+ PLA     P    + Q           P +  P S P    P+    P
Sbjct: 206 HHSLTAHGAPERPLAATSAAPPPQPQPQ----------PPPQPEPRSVP---QPEPEPEP 252

Query: 694 SQLLGSSSDSLPTSPP--PDDSLSLKVFRCLVCQAFSTDSLELLLYHCSIGRSLPEAEWK 751
            +      ++ PT  P  P++  +   FRC VC    T S   L  H            K
Sbjct: 253 ER------EATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSW-FLKGHMR----------K 295

Query: 752 EVAGDTHRCKLCCYGTQLKANFQLHLKTDKHAQKYQLAAHLREGGGAMG---TPSPASLG 808
             A   H C +C  G   K  + L      HA K      LR  G A G    P P  LG
Sbjct: 296 HKASFDHACPVC--GRCFKEPWFLKNHMKVHASK---LGPLRAPGPASGPARAPQPPDLG 350



 Score = 42.0 bits (97), Expect = 0.008
 Identities = 31/118 (26%), Positives = 44/118 (37%), Gaps = 33/118 (27%)

Query: 455 CPKCNWHYKYQQTLDVHMREKHPESNSHCSYCSAGGAHPRLARGESYNCGYKPYRCDVCN 514
           CP C   ++    L VH+R                            + G +PY+C  C+
Sbjct: 500 CPFCGKSFRSAHHLKVHLR---------------------------VHTGERPYKCPHCD 532

Query: 515 YSTTTKGNLSIHMQSDKHLANLQGFQAGPGGQGSPPEAS---LPPSAGDKEPKTKSSW 569
           Y+ T  G+L  H+Q   H     G  AGPG    PP  S     P +G K     ++W
Sbjct: 533 YAGTQSGSLKYHLQR-HHREQRSG--AGPGPPPEPPPPSQRGSAPQSGAKPSPQPATW 587



 Score = 38.9 bits (89), Expect = 0.070
 Identities = 46/206 (22%), Positives = 71/206 (34%), Gaps = 26/206 (12%)

Query: 438 SSHMSLLHSR--NSCKTLKCPKCNWHYKYQQTLDVHMREKHPESNSHCSYCSAGGAHPRL 495
           S+H   +H R     +  KCP C++      +L  H++  H E  S           P  
Sbjct: 509 SAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSGAGPGPPPEPPPPS 568

Query: 496 ARGESYNCGYKPYRCDVCNYSTTTKGNLSIHMQSD--------KHLANLQGFQAGPGGQG 547
            RG +   G KP        +T  +G  S    S         K  +  +  + G GG+ 
Sbjct: 569 QRGSAPQSGAKPSP----QPATWVEGASSPRPPSSGAGPGSRRKPASPGRTLRNGRGGEA 624

Query: 548 SPPEASLPPSAGDKEPKTKSSWQCKVCSYETNISRNLRIHMTSEKHMQNVLMLHQGLPLG 607
            P + SL    G +     +  +C  C + T     + +H+          + H     G
Sbjct: 625 EPLDLSLRAGPGGEAGPGGALHRCLFCPFATGAPELMALHLQ---------VHHSRRARG 675

Query: 608 LPPGLMGPGPP---PPPGATPTSPPE 630
             P      PP    P G TP SP +
Sbjct: 676 RRPPQADASPPYARVPSGETPPSPSQ 701



 Score = 37.7 bits (86), Expect = 0.15
 Identities = 51/219 (23%), Positives = 79/219 (36%), Gaps = 55/219 (25%)

Query: 473 REKHPESNS-HCSYCSAGGAHPRLARGESYNCGYKPYRCDVCNYSTTTKGNLSIHMQSDK 531
           R + P S++  C YC  G       R    +  ++P++C +C++ ++ +  L +H     
Sbjct: 154 RPQAPSSSAFRCPYCK-GKFRTSAERERHLHILHRPWKCGLCSFGSSQEEEL-LHHSLTA 211

Query: 532 HLAN---LQGFQAGPGGQGSP-------------------PEASLPPS---AGDKEPKTK 566
           H A    L    A P  Q  P                   PE    P+   A  +EP   
Sbjct: 212 HGAPERPLAATSAAPPPQPQPQPPPQPEPRSVPQPEPEPEPEREATPTPAPAAPEEPPAP 271

Query: 567 SSWQCKVCSYETNISRNLRIHMTSEK------------------HMQNVLMLHQGLPLGL 608
             ++C+VC      S  L+ HM   K                   ++N + +H    LG 
Sbjct: 272 PEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHAS-KLG- 329

Query: 609 PPGLMGPGPPPPPGATPTSPPEL----FQYFGPQALGQP 643
              L  PGP   P   P  PP+L    ++  GP  L  P
Sbjct: 330 --PLRAPGPASGPARAP-QPPDLGLLAYEPLGPALLLAP 365



 Score = 34.7 bits (78), Expect = 1.3
 Identities = 44/161 (27%), Positives = 55/161 (34%), Gaps = 12/161 (7%)

Query: 2405 AGPGRPLPQRPMPDQTNTSTAGTTDPVPGPPTEPLGDKVSSERKPV--AGPTSSSNDALK 2462
            AGPG P P+ P P Q  ++      P P P T   G   SS R P   AGP S    A  
Sbjct: 556  AGPGPP-PEPPPPSQRGSAPQSGAKPSPQPATWVEG--ASSPRPPSSGAGPGSRRKPASP 612

Query: 2463 NLKALKTTVPALLGGQFLPFPLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNPMI 2522
                   T+    GG+  P  L    G    A  G  L    F         L  ++  +
Sbjct: 613  G-----RTLRNGRGGEAEPLDLSLRAGPGGEAGPGGALHRCLFCPFATGAPELMALHLQV 667

Query: 2523 --PQTLIGLLPNALLQPPPQPPEPTATAPPKPPELPAPGEG 2561
               +   G  P      PP    P+   PP P +    G G
Sbjct: 668  HHSRRARGRRPPQADASPPYARVPSGETPPSPSQEGEEGSG 708



 Score = 32.7 bits (73), Expect = 5.0
 Identities = 45/188 (23%), Positives = 65/188 (34%), Gaps = 38/188 (20%)

Query: 569 WQCKVCSYETNISRNLRIHMTSEKHMQNVLMLHQGLPLGLPPGLMGPGPPPPPGATPTSP 628
           ++C  C Y    S +L+ H+      Q                  G GP PPP   P S 
Sbjct: 526 YKCPHCDYAGTQSGSLKYHLQRHHREQR----------------SGAGPGPPPEPPPPSQ 569

Query: 629 PELFQYFGPQALGQPQTPLAGPGLRPDKPLEAQLLLNGFHHVGAPARKFPTSAPGSLSPD 688
                  G +   QP T + G    P  P             G  +R+ P S PG    +
Sbjct: 570 RGSAPQSGAKPSPQPATWVEGAS-SPRPPSSG---------AGPGSRRKPAS-PGRTLRN 618

Query: 689 AHLPPSQLLGSSSDSLPTSPPPDDSLSLKVFRCLVCQAFSTDSLELLLYHCSI------- 741
                ++ L     SL   P  +      + RCL C  F+T + EL+  H  +       
Sbjct: 619 GRGGEAEPLDL---SLRAGPGGEAGPGGALHRCLFC-PFATGAPELMALHLQVHHSRRAR 674

Query: 742 GRSLPEAE 749
           GR  P+A+
Sbjct: 675 GRRPPQAD 682


>gi|156415998 zinc finger protein 219 [Homo sapiens]
          Length = 722

 Score = 65.5 bits (158), Expect = 7e-10
 Identities = 107/431 (24%), Positives = 147/431 (34%), Gaps = 105/431 (24%)

Query: 1517 PAPVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPSSPPDPLPNEAARTAAKA 1576
            P   L+  +A PPP PQP           +PP   E     P S P P P          
Sbjct: 215  PERPLAATSAAPPPQPQP-----------QPPPQPE-----PRSVPQPEPEP-------- 250

Query: 1577 LLENFGFELVIQYNEGKQAVPPPPTPPPPEALGGGDKLACGACGKLFSNMLILKTHEEHV 1636
                          E ++   P P P  PE      +  C  CG+ F+    LK H    
Sbjct: 251  --------------EPEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKH 296

Query: 1637 HRRF---LPFEALSRYAAQFRKSYDSLYP----PLAEP---------PKPPDGSLDSPVP 1680
               F    P          F K++  ++     PL  P         P+PPD  L +  P
Sbjct: 297  KASFDHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAPGPASGPARAPQPPDLGLLAYEP 356

Query: 1681 HLGPPFLV-PEPEAGGTRAPEE-----RSRAGGHWPIEEEES-----SRGNLPPL---VP 1726
             LGP  L+ P P     R P         RAG   P  E        S G   PL   +P
Sbjct: 357  -LGPALLLAPAPTPAERREPPSLLGYLSLRAGEGRPNGEGAEPGPGRSFGGFRPLSSALP 415

Query: 1727 AGRRFSRTKFTEFQTQALQSFFET-----------SAYPKDGE-VERLASLLGLASRVVV 1774
            A  R  R +  E + + +++  ET           S +P+ GE     AS  G  +R   
Sbjct: 416  ARARRHRAEEPEEEEEVVEAEEETWARGRSLGSLASLHPRPGEGPGHSASAAGAQARSTA 475

Query: 1775 VWFQNARQKARKNACEGGSMPTGGGTGGASGCRRCHATFSCVFELVRHLKKCYDDQTLE- 1833
               +N           GG+ P GG       C  C  +F     L  HL+    ++  + 
Sbjct: 476  TQEEN-------GLLVGGTRPEGGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKC 528

Query: 1834 --EEEEEAERGEEEEEVEEEEVEEEQGLEPPAGPEGPLPEPPDGEELSQAEATKAGGKEP 1891
               +    + G  +  ++    E+  G    AGP GP PEPP   +          G  P
Sbjct: 529  PHCDYAGTQSGSLKYHLQRHHREQRSG----AGP-GPPPEPPPPSQ---------RGSAP 574

Query: 1892 EEKATPSPSPA 1902
            +  A PSP PA
Sbjct: 575  QSGAKPSPQPA 585



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 114/487 (23%), Positives = 158/487 (32%), Gaps = 114/487 (23%)

Query: 1236 PEPPLASVEVPDKPSGSPGQPPSPAPSPVPEPDAQAEDVAPPPTMAEEEEGTTGELRSAE 1295
            PE PLA+      P   P  PP P P  VP+P+ + E          E E T        
Sbjct: 215  PERPLAATSAAPPPQPQPQPPPQPEPRSVPQPEPEPE---------PEREAT------PT 259

Query: 1296 PAPADSRHPLTYRKTTNFALDKFLDPARP-YKCTVCKESFTQKNILLVHYNSVSHLHKMK 1354
            PAPA    P                PA P ++C VC +SFTQ   L  H        +  
Sbjct: 260  PAPAAPEEP----------------PAPPEFRCQVCGQSFTQSWFLKGHM-------RKH 296

Query: 1355 KAAIDPSAPARGEAGAPPTTTAATDKPFKCTVCRVSYNQSSTLEIHMRSVLHQTRSRGTK 1414
            KA+ D +                      C VC   + +   L+ HM+  +H ++    +
Sbjct: 297  KASFDHA----------------------CPVCGRCFKEPWFLKNHMK--VHASKLGPLR 332

Query: 1415 TDSKIEGPERSQEEPKEGETEGEVGTEKKGPDTSGFISGLPFLSPPPPPLDLHRFPAPLF 1474
                  GP R+ + P      G +  E  GP           L+P P P +  R P  L 
Sbjct: 333  APGPASGPARAPQPP----DLGLLAYEPLGPAL--------LLAPAPTPAE-RREPPSLL 379

Query: 1475 TPPVLPPFPLVPESLLKLQQQQLLLPFYLHDLKVGPKLTLAGPAPVLS-LPAATPPPPPQ 1533
                L      P                    + GP  +  G  P+ S LPA       +
Sbjct: 380  GYLSLRAGEGRPNG---------------EGAEPGPGRSFGGFRPLSSALPARARRHRAE 424

Query: 1534 PPKAELAEREWERPPMAKEGNEAGPSSPPDPLPNEAARTAAKALLENFGFELVIQYNEGK 1593
             P+ E    E E    A+ G   G  +   P P E    +A A     G +      + +
Sbjct: 425  EPEEEEEVVEAEEETWAR-GRSLGSLASLHPRPGEGPGHSASAA----GAQARSTATQEE 479

Query: 1594 QAVPPPPTPPPPEALGGGDKLACGACGKLFSNMLILKTHEEHVHRRFLPFE--------- 1644
              +    T   PE   G     C  CGK F +   LK H   VH    P++         
Sbjct: 480  NGLLVGGT--RPEGGRGATGKDCPFCGKSFRSAHHLKVH-LRVHTGERPYKCPHCDYAGT 536

Query: 1645 ---ALSRYAAQFRKSYDSLYPPLAEPPKPPDGSLDSPVPHLG-PPFLVPEPEAGGTRAPE 1700
               +L  +  +  +   S   P   PP+PP  S     P  G  P   P     G  +P 
Sbjct: 537  QSGSLKYHLQRHHREQRSGAGP-GPPPEPPPPSQRGSAPQSGAKPSPQPATWVEGASSPR 595

Query: 1701 ERSRAGG 1707
              S   G
Sbjct: 596  PPSSGAG 602



 Score = 52.4 bits (124), Expect = 6e-06
 Identities = 111/510 (21%), Positives = 156/510 (30%), Gaps = 122/510 (23%)

Query: 1788 ACEGGSMPTGGGTGGASGCRRCHATFSCVFELVRHLK------KCYDDQTLEEEEEEAER 1841
            A EG + P    +  A  C  C   F    E  RHL       KC        +EEE   
Sbjct: 148  ATEGLARPQAPSSS-AFRCPYCKGKFRTSAERERHLHILHRPWKCGLCSFGSSQEEELLH 206

Query: 1842 GEEEEEVEEEEVEEEQGLEPPAGPEGPLPEPPDGEELSQAEATKAGGKEPEEKATPSPSP 1901
                     E         PP  P+   P  P+   + Q E       EPE +ATP+P+P
Sbjct: 207  HSLTAHGAPERPLAATSAAPPPQPQPQPPPQPEPRSVPQPEPEP----EPEREATPTPAP 262

Query: 1902 A--------------------------------------HTCDQCAISFSSQDLLTSHRR 1923
            A                                      H C  C   F     L +H +
Sbjct: 263  AAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMK 322

Query: 1924 LHFL---------PSLQPSAPPQLLDLPLLVFGERNP-LVAATSPMPGPPLKRKHEDGSL 1973
            +H           P+  P+  PQ  DL LL +    P L+ A +P P    +     G L
Sbjct: 323  VHASKLGPLRAPGPASGPARAPQPPDLGLLAYEPLGPALLLAPAPTPAERREPPSLLGYL 382

Query: 1974 SPTGSEAGGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKR 2033
            S    E    GEG  P   R      P    +        +   R   +   EE  + + 
Sbjct: 383  SLRAGEGRPNGEGAEPGPGRSFGGFRPLSSAL-------PARARRHRAEEPEEEEEVVEA 435

Query: 2034 VVQVWFQNTRARERKGQFRSTPGGVP--SPAVKPPATATPASLPKFNLLLGKVDDGTGRE 2091
              + W +  R+          PG  P  S +       + A+  +  LL+G      GR 
Sbjct: 436  EEETWARG-RSLGSLASLHPRPGEGPGHSASAAGAQARSTATQEENGLLVGGTRPEGGRG 494

Query: 2092 APKREAP--AFPYPTA-------TLASGPQPFLPP----------------------GKE 2120
            A  ++ P     + +A        + +G +P+  P                       + 
Sbjct: 495  ATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRS 554

Query: 2121 ATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPES----EACSLSAGDLSDSSASSLAEPE 2176
               P P P     PPPP      P+   K SP+     E  S      S +   S  +P 
Sbjct: 555  GAGPGPPPE----PPPPSQRGSAPQSGAKPSPQPATWVEGASSPRPPSSGAGPGSRRKPA 610

Query: 2177 SP------GAGGTS--------GGPGGGTG 2192
            SP      G GG +         GPGG  G
Sbjct: 611  SPGRTLRNGRGGEAEPLDLSLRAGPGGEAG 640



 Score = 46.6 bits (109), Expect = 3e-04
 Identities = 99/420 (23%), Positives = 145/420 (34%), Gaps = 80/420 (19%)

Query: 398 EGGTLPAPVGSPEDPSDPPQPYRL-ADDYTPAPAAFQGLSLSSHMSLLHSRNSCKTLKCP 456
           EG    AP G    PS P     L    Y+  PA   G      +S   SR   +   CP
Sbjct: 2   EGSRPRAPSGHLA-PSPPAFDGELDLQRYSNGPAVSAGSLGMGAVSWSESRAGERRFPCP 60

Query: 457 KCNWHYKYQQTLDVHMREKHPESNS-HCSYCSAGGAHPRLARGESYNCGYKPYRCDVCNY 515
            C   +++   L +H+R  HP + +  C +C    A   L R  S+   ++P R      
Sbjct: 61  VCGKRFRFNSILALHLR-AHPGAQAFQCPHCGHRAAQRALLR--SHLRTHQPER----PR 113

Query: 516 STTTKGNLSIHMQSDKHLANLQGFQAGPGGQGSPPEASLPPSAGDKEPKTKSSWQCKVC- 574
           S   +  L +  ++    A L   ++  G Q +P    L       +  + S+++C  C 
Sbjct: 114 SPAARLLLELEERALLREARLGRARSSGGMQATPATEGL----ARPQAPSSSAFRCPYCK 169

Query: 575 -SYETNISRNLRIHMTSEKHMQNVLMLHQGLPLGLPPGLMGPGPPPPPGATPTSPPELFQ 633
             + T+  R   +H           +LH+    GL              +  +S  E   
Sbjct: 170 GKFRTSAERERHLH-----------ILHRPWKCGL-------------CSFGSSQEEELL 205

Query: 634 YFGPQALGQPQTPLAGPGLRPDKPLEAQLLLNGFHHVGAPARKFPTSAPGSLSPDAHLPP 693
           +    A G P+ PLA     P    + Q           P +  P S P    P+    P
Sbjct: 206 HHSLTAHGAPERPLAATSAAPPPQPQPQ----------PPPQPEPRSVP---QPEPEPEP 252

Query: 694 SQLLGSSSDSLPTSPP--PDDSLSLKVFRCLVCQAFSTDSLELLLYHCSIGRSLPEAEWK 751
            +      ++ PT  P  P++  +   FRC VC    T S   L  H            K
Sbjct: 253 ER------EATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSW-FLKGHMR----------K 295

Query: 752 EVAGDTHRCKLCCYGTQLKANFQLHLKTDKHAQKYQLAAHLREGGGAMG---TPSPASLG 808
             A   H C +C  G   K  + L      HA K      LR  G A G    P P  LG
Sbjct: 296 HKASFDHACPVC--GRCFKEPWFLKNHMKVHASK---LGPLRAPGPASGPARAPQPPDLG 350



 Score = 42.0 bits (97), Expect = 0.008
 Identities = 31/118 (26%), Positives = 44/118 (37%), Gaps = 33/118 (27%)

Query: 455 CPKCNWHYKYQQTLDVHMREKHPESNSHCSYCSAGGAHPRLARGESYNCGYKPYRCDVCN 514
           CP C   ++    L VH+R                            + G +PY+C  C+
Sbjct: 500 CPFCGKSFRSAHHLKVHLR---------------------------VHTGERPYKCPHCD 532

Query: 515 YSTTTKGNLSIHMQSDKHLANLQGFQAGPGGQGSPPEAS---LPPSAGDKEPKTKSSW 569
           Y+ T  G+L  H+Q   H     G  AGPG    PP  S     P +G K     ++W
Sbjct: 533 YAGTQSGSLKYHLQR-HHREQRSG--AGPGPPPEPPPPSQRGSAPQSGAKPSPQPATW 587



 Score = 38.9 bits (89), Expect = 0.070
 Identities = 46/206 (22%), Positives = 71/206 (34%), Gaps = 26/206 (12%)

Query: 438 SSHMSLLHSR--NSCKTLKCPKCNWHYKYQQTLDVHMREKHPESNSHCSYCSAGGAHPRL 495
           S+H   +H R     +  KCP C++      +L  H++  H E  S           P  
Sbjct: 509 SAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSGAGPGPPPEPPPPS 568

Query: 496 ARGESYNCGYKPYRCDVCNYSTTTKGNLSIHMQSD--------KHLANLQGFQAGPGGQG 547
            RG +   G KP        +T  +G  S    S         K  +  +  + G GG+ 
Sbjct: 569 QRGSAPQSGAKPSP----QPATWVEGASSPRPPSSGAGPGSRRKPASPGRTLRNGRGGEA 624

Query: 548 SPPEASLPPSAGDKEPKTKSSWQCKVCSYETNISRNLRIHMTSEKHMQNVLMLHQGLPLG 607
            P + SL    G +     +  +C  C + T     + +H+          + H     G
Sbjct: 625 EPLDLSLRAGPGGEAGPGGALHRCLFCPFATGAPELMALHLQ---------VHHSRRARG 675

Query: 608 LPPGLMGPGPP---PPPGATPTSPPE 630
             P      PP    P G TP SP +
Sbjct: 676 RRPPQADASPPYARVPSGETPPSPSQ 701



 Score = 37.7 bits (86), Expect = 0.15
 Identities = 51/219 (23%), Positives = 79/219 (36%), Gaps = 55/219 (25%)

Query: 473 REKHPESNS-HCSYCSAGGAHPRLARGESYNCGYKPYRCDVCNYSTTTKGNLSIHMQSDK 531
           R + P S++  C YC  G       R    +  ++P++C +C++ ++ +  L +H     
Sbjct: 154 RPQAPSSSAFRCPYCK-GKFRTSAERERHLHILHRPWKCGLCSFGSSQEEEL-LHHSLTA 211

Query: 532 HLAN---LQGFQAGPGGQGSP-------------------PEASLPPS---AGDKEPKTK 566
           H A    L    A P  Q  P                   PE    P+   A  +EP   
Sbjct: 212 HGAPERPLAATSAAPPPQPQPQPPPQPEPRSVPQPEPEPEPEREATPTPAPAAPEEPPAP 271

Query: 567 SSWQCKVCSYETNISRNLRIHMTSEK------------------HMQNVLMLHQGLPLGL 608
             ++C+VC      S  L+ HM   K                   ++N + +H    LG 
Sbjct: 272 PEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHAS-KLG- 329

Query: 609 PPGLMGPGPPPPPGATPTSPPEL----FQYFGPQALGQP 643
              L  PGP   P   P  PP+L    ++  GP  L  P
Sbjct: 330 --PLRAPGPASGPARAP-QPPDLGLLAYEPLGPALLLAP 365



 Score = 34.7 bits (78), Expect = 1.3
 Identities = 44/161 (27%), Positives = 55/161 (34%), Gaps = 12/161 (7%)

Query: 2405 AGPGRPLPQRPMPDQTNTSTAGTTDPVPGPPTEPLGDKVSSERKPV--AGPTSSSNDALK 2462
            AGPG P P+ P P Q  ++      P P P T   G   SS R P   AGP S    A  
Sbjct: 556  AGPGPP-PEPPPPSQRGSAPQSGAKPSPQPATWVEG--ASSPRPPSSGAGPGSRRKPASP 612

Query: 2463 NLKALKTTVPALLGGQFLPFPLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNPMI 2522
                   T+    GG+  P  L    G    A  G  L    F         L  ++  +
Sbjct: 613  G-----RTLRNGRGGEAEPLDLSLRAGPGGEAGPGGALHRCLFCPFATGAPELMALHLQV 667

Query: 2523 --PQTLIGLLPNALLQPPPQPPEPTATAPPKPPELPAPGEG 2561
               +   G  P      PP    P+   PP P +    G G
Sbjct: 668  HHSRRARGRRPPQADASPPYARVPSGETPPSPSQEGEEGSG 708



 Score = 32.7 bits (73), Expect = 5.0
 Identities = 45/188 (23%), Positives = 65/188 (34%), Gaps = 38/188 (20%)

Query: 569 WQCKVCSYETNISRNLRIHMTSEKHMQNVLMLHQGLPLGLPPGLMGPGPPPPPGATPTSP 628
           ++C  C Y    S +L+ H+      Q                  G GP PPP   P S 
Sbjct: 526 YKCPHCDYAGTQSGSLKYHLQRHHREQR----------------SGAGPGPPPEPPPPSQ 569

Query: 629 PELFQYFGPQALGQPQTPLAGPGLRPDKPLEAQLLLNGFHHVGAPARKFPTSAPGSLSPD 688
                  G +   QP T + G    P  P             G  +R+ P S PG    +
Sbjct: 570 RGSAPQSGAKPSPQPATWVEGAS-SPRPPSSG---------AGPGSRRKPAS-PGRTLRN 618

Query: 689 AHLPPSQLLGSSSDSLPTSPPPDDSLSLKVFRCLVCQAFSTDSLELLLYHCSI------- 741
                ++ L     SL   P  +      + RCL C  F+T + EL+  H  +       
Sbjct: 619 GRGGEAEPLDL---SLRAGPGGEAGPGGALHRCLFC-PFATGAPELMALHLQVHHSRRAR 674

Query: 742 GRSLPEAE 749
           GR  P+A+
Sbjct: 675 GRRPPQAD 682


>gi|156415996 zinc finger protein 219 [Homo sapiens]
          Length = 722

 Score = 65.5 bits (158), Expect = 7e-10
 Identities = 107/431 (24%), Positives = 147/431 (34%), Gaps = 105/431 (24%)

Query: 1517 PAPVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPSSPPDPLPNEAARTAAKA 1576
            P   L+  +A PPP PQP           +PP   E     P S P P P          
Sbjct: 215  PERPLAATSAAPPPQPQP-----------QPPPQPE-----PRSVPQPEPEP-------- 250

Query: 1577 LLENFGFELVIQYNEGKQAVPPPPTPPPPEALGGGDKLACGACGKLFSNMLILKTHEEHV 1636
                          E ++   P P P  PE      +  C  CG+ F+    LK H    
Sbjct: 251  --------------EPEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKH 296

Query: 1637 HRRF---LPFEALSRYAAQFRKSYDSLYP----PLAEP---------PKPPDGSLDSPVP 1680
               F    P          F K++  ++     PL  P         P+PPD  L +  P
Sbjct: 297  KASFDHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAPGPASGPARAPQPPDLGLLAYEP 356

Query: 1681 HLGPPFLV-PEPEAGGTRAPEE-----RSRAGGHWPIEEEES-----SRGNLPPL---VP 1726
             LGP  L+ P P     R P         RAG   P  E        S G   PL   +P
Sbjct: 357  -LGPALLLAPAPTPAERREPPSLLGYLSLRAGEGRPNGEGAEPGPGRSFGGFRPLSSALP 415

Query: 1727 AGRRFSRTKFTEFQTQALQSFFET-----------SAYPKDGE-VERLASLLGLASRVVV 1774
            A  R  R +  E + + +++  ET           S +P+ GE     AS  G  +R   
Sbjct: 416  ARARRHRAEEPEEEEEVVEAEEETWARGRSLGSLASLHPRPGEGPGHSASAAGAQARSTA 475

Query: 1775 VWFQNARQKARKNACEGGSMPTGGGTGGASGCRRCHATFSCVFELVRHLKKCYDDQTLE- 1833
               +N           GG+ P GG       C  C  +F     L  HL+    ++  + 
Sbjct: 476  TQEEN-------GLLVGGTRPEGGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKC 528

Query: 1834 --EEEEEAERGEEEEEVEEEEVEEEQGLEPPAGPEGPLPEPPDGEELSQAEATKAGGKEP 1891
               +    + G  +  ++    E+  G    AGP GP PEPP   +          G  P
Sbjct: 529  PHCDYAGTQSGSLKYHLQRHHREQRSG----AGP-GPPPEPPPPSQ---------RGSAP 574

Query: 1892 EEKATPSPSPA 1902
            +  A PSP PA
Sbjct: 575  QSGAKPSPQPA 585



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 114/487 (23%), Positives = 158/487 (32%), Gaps = 114/487 (23%)

Query: 1236 PEPPLASVEVPDKPSGSPGQPPSPAPSPVPEPDAQAEDVAPPPTMAEEEEGTTGELRSAE 1295
            PE PLA+      P   P  PP P P  VP+P+ + E          E E T        
Sbjct: 215  PERPLAATSAAPPPQPQPQPPPQPEPRSVPQPEPEPE---------PEREAT------PT 259

Query: 1296 PAPADSRHPLTYRKTTNFALDKFLDPARP-YKCTVCKESFTQKNILLVHYNSVSHLHKMK 1354
            PAPA    P                PA P ++C VC +SFTQ   L  H        +  
Sbjct: 260  PAPAAPEEP----------------PAPPEFRCQVCGQSFTQSWFLKGHM-------RKH 296

Query: 1355 KAAIDPSAPARGEAGAPPTTTAATDKPFKCTVCRVSYNQSSTLEIHMRSVLHQTRSRGTK 1414
            KA+ D +                      C VC   + +   L+ HM+  +H ++    +
Sbjct: 297  KASFDHA----------------------CPVCGRCFKEPWFLKNHMK--VHASKLGPLR 332

Query: 1415 TDSKIEGPERSQEEPKEGETEGEVGTEKKGPDTSGFISGLPFLSPPPPPLDLHRFPAPLF 1474
                  GP R+ + P      G +  E  GP           L+P P P +  R P  L 
Sbjct: 333  APGPASGPARAPQPP----DLGLLAYEPLGPAL--------LLAPAPTPAE-RREPPSLL 379

Query: 1475 TPPVLPPFPLVPESLLKLQQQQLLLPFYLHDLKVGPKLTLAGPAPVLS-LPAATPPPPPQ 1533
                L      P                    + GP  +  G  P+ S LPA       +
Sbjct: 380  GYLSLRAGEGRPNG---------------EGAEPGPGRSFGGFRPLSSALPARARRHRAE 424

Query: 1534 PPKAELAEREWERPPMAKEGNEAGPSSPPDPLPNEAARTAAKALLENFGFELVIQYNEGK 1593
             P+ E    E E    A+ G   G  +   P P E    +A A     G +      + +
Sbjct: 425  EPEEEEEVVEAEEETWAR-GRSLGSLASLHPRPGEGPGHSASAA----GAQARSTATQEE 479

Query: 1594 QAVPPPPTPPPPEALGGGDKLACGACGKLFSNMLILKTHEEHVHRRFLPFE--------- 1644
              +    T   PE   G     C  CGK F +   LK H   VH    P++         
Sbjct: 480  NGLLVGGT--RPEGGRGATGKDCPFCGKSFRSAHHLKVH-LRVHTGERPYKCPHCDYAGT 536

Query: 1645 ---ALSRYAAQFRKSYDSLYPPLAEPPKPPDGSLDSPVPHLG-PPFLVPEPEAGGTRAPE 1700
               +L  +  +  +   S   P   PP+PP  S     P  G  P   P     G  +P 
Sbjct: 537  QSGSLKYHLQRHHREQRSGAGP-GPPPEPPPPSQRGSAPQSGAKPSPQPATWVEGASSPR 595

Query: 1701 ERSRAGG 1707
              S   G
Sbjct: 596  PPSSGAG 602



 Score = 52.4 bits (124), Expect = 6e-06
 Identities = 111/510 (21%), Positives = 156/510 (30%), Gaps = 122/510 (23%)

Query: 1788 ACEGGSMPTGGGTGGASGCRRCHATFSCVFELVRHLK------KCYDDQTLEEEEEEAER 1841
            A EG + P    +  A  C  C   F    E  RHL       KC        +EEE   
Sbjct: 148  ATEGLARPQAPSSS-AFRCPYCKGKFRTSAERERHLHILHRPWKCGLCSFGSSQEEELLH 206

Query: 1842 GEEEEEVEEEEVEEEQGLEPPAGPEGPLPEPPDGEELSQAEATKAGGKEPEEKATPSPSP 1901
                     E         PP  P+   P  P+   + Q E       EPE +ATP+P+P
Sbjct: 207  HSLTAHGAPERPLAATSAAPPPQPQPQPPPQPEPRSVPQPEPEP----EPEREATPTPAP 262

Query: 1902 A--------------------------------------HTCDQCAISFSSQDLLTSHRR 1923
            A                                      H C  C   F     L +H +
Sbjct: 263  AAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMK 322

Query: 1924 LHFL---------PSLQPSAPPQLLDLPLLVFGERNP-LVAATSPMPGPPLKRKHEDGSL 1973
            +H           P+  P+  PQ  DL LL +    P L+ A +P P    +     G L
Sbjct: 323  VHASKLGPLRAPGPASGPARAPQPPDLGLLAYEPLGPALLLAPAPTPAERREPPSLLGYL 382

Query: 1974 SPTGSEAGGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKR 2033
            S    E    GEG  P   R      P    +        +   R   +   EE  + + 
Sbjct: 383  SLRAGEGRPNGEGAEPGPGRSFGGFRPLSSAL-------PARARRHRAEEPEEEEEVVEA 435

Query: 2034 VVQVWFQNTRARERKGQFRSTPGGVP--SPAVKPPATATPASLPKFNLLLGKVDDGTGRE 2091
              + W +  R+          PG  P  S +       + A+  +  LL+G      GR 
Sbjct: 436  EEETWARG-RSLGSLASLHPRPGEGPGHSASAAGAQARSTATQEENGLLVGGTRPEGGRG 494

Query: 2092 APKREAP--AFPYPTA-------TLASGPQPFLPP----------------------GKE 2120
            A  ++ P     + +A        + +G +P+  P                       + 
Sbjct: 495  ATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRS 554

Query: 2121 ATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPES----EACSLSAGDLSDSSASSLAEPE 2176
               P P P     PPPP      P+   K SP+     E  S      S +   S  +P 
Sbjct: 555  GAGPGPPPE----PPPPSQRGSAPQSGAKPSPQPATWVEGASSPRPPSSGAGPGSRRKPA 610

Query: 2177 SP------GAGGTS--------GGPGGGTG 2192
            SP      G GG +         GPGG  G
Sbjct: 611  SPGRTLRNGRGGEAEPLDLSLRAGPGGEAG 640



 Score = 46.6 bits (109), Expect = 3e-04
 Identities = 99/420 (23%), Positives = 145/420 (34%), Gaps = 80/420 (19%)

Query: 398 EGGTLPAPVGSPEDPSDPPQPYRL-ADDYTPAPAAFQGLSLSSHMSLLHSRNSCKTLKCP 456
           EG    AP G    PS P     L    Y+  PA   G      +S   SR   +   CP
Sbjct: 2   EGSRPRAPSGHLA-PSPPAFDGELDLQRYSNGPAVSAGSLGMGAVSWSESRAGERRFPCP 60

Query: 457 KCNWHYKYQQTLDVHMREKHPESNS-HCSYCSAGGAHPRLARGESYNCGYKPYRCDVCNY 515
            C   +++   L +H+R  HP + +  C +C    A   L R  S+   ++P R      
Sbjct: 61  VCGKRFRFNSILALHLR-AHPGAQAFQCPHCGHRAAQRALLR--SHLRTHQPER----PR 113

Query: 516 STTTKGNLSIHMQSDKHLANLQGFQAGPGGQGSPPEASLPPSAGDKEPKTKSSWQCKVC- 574
           S   +  L +  ++    A L   ++  G Q +P    L       +  + S+++C  C 
Sbjct: 114 SPAARLLLELEERALLREARLGRARSSGGMQATPATEGL----ARPQAPSSSAFRCPYCK 169

Query: 575 -SYETNISRNLRIHMTSEKHMQNVLMLHQGLPLGLPPGLMGPGPPPPPGATPTSPPELFQ 633
             + T+  R   +H           +LH+    GL              +  +S  E   
Sbjct: 170 GKFRTSAERERHLH-----------ILHRPWKCGL-------------CSFGSSQEEELL 205

Query: 634 YFGPQALGQPQTPLAGPGLRPDKPLEAQLLLNGFHHVGAPARKFPTSAPGSLSPDAHLPP 693
           +    A G P+ PLA     P    + Q           P +  P S P    P+    P
Sbjct: 206 HHSLTAHGAPERPLAATSAAPPPQPQPQ----------PPPQPEPRSVP---QPEPEPEP 252

Query: 694 SQLLGSSSDSLPTSPP--PDDSLSLKVFRCLVCQAFSTDSLELLLYHCSIGRSLPEAEWK 751
            +      ++ PT  P  P++  +   FRC VC    T S   L  H            K
Sbjct: 253 ER------EATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSW-FLKGHMR----------K 295

Query: 752 EVAGDTHRCKLCCYGTQLKANFQLHLKTDKHAQKYQLAAHLREGGGAMG---TPSPASLG 808
             A   H C +C  G   K  + L      HA K      LR  G A G    P P  LG
Sbjct: 296 HKASFDHACPVC--GRCFKEPWFLKNHMKVHASK---LGPLRAPGPASGPARAPQPPDLG 350



 Score = 42.0 bits (97), Expect = 0.008
 Identities = 31/118 (26%), Positives = 44/118 (37%), Gaps = 33/118 (27%)

Query: 455 CPKCNWHYKYQQTLDVHMREKHPESNSHCSYCSAGGAHPRLARGESYNCGYKPYRCDVCN 514
           CP C   ++    L VH+R                            + G +PY+C  C+
Sbjct: 500 CPFCGKSFRSAHHLKVHLR---------------------------VHTGERPYKCPHCD 532

Query: 515 YSTTTKGNLSIHMQSDKHLANLQGFQAGPGGQGSPPEAS---LPPSAGDKEPKTKSSW 569
           Y+ T  G+L  H+Q   H     G  AGPG    PP  S     P +G K     ++W
Sbjct: 533 YAGTQSGSLKYHLQR-HHREQRSG--AGPGPPPEPPPPSQRGSAPQSGAKPSPQPATW 587



 Score = 38.9 bits (89), Expect = 0.070
 Identities = 46/206 (22%), Positives = 71/206 (34%), Gaps = 26/206 (12%)

Query: 438 SSHMSLLHSR--NSCKTLKCPKCNWHYKYQQTLDVHMREKHPESNSHCSYCSAGGAHPRL 495
           S+H   +H R     +  KCP C++      +L  H++  H E  S           P  
Sbjct: 509 SAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSGAGPGPPPEPPPPS 568

Query: 496 ARGESYNCGYKPYRCDVCNYSTTTKGNLSIHMQSD--------KHLANLQGFQAGPGGQG 547
            RG +   G KP        +T  +G  S    S         K  +  +  + G GG+ 
Sbjct: 569 QRGSAPQSGAKPSP----QPATWVEGASSPRPPSSGAGPGSRRKPASPGRTLRNGRGGEA 624

Query: 548 SPPEASLPPSAGDKEPKTKSSWQCKVCSYETNISRNLRIHMTSEKHMQNVLMLHQGLPLG 607
            P + SL    G +     +  +C  C + T     + +H+          + H     G
Sbjct: 625 EPLDLSLRAGPGGEAGPGGALHRCLFCPFATGAPELMALHLQ---------VHHSRRARG 675

Query: 608 LPPGLMGPGPP---PPPGATPTSPPE 630
             P      PP    P G TP SP +
Sbjct: 676 RRPPQADASPPYARVPSGETPPSPSQ 701



 Score = 37.7 bits (86), Expect = 0.15
 Identities = 51/219 (23%), Positives = 79/219 (36%), Gaps = 55/219 (25%)

Query: 473 REKHPESNS-HCSYCSAGGAHPRLARGESYNCGYKPYRCDVCNYSTTTKGNLSIHMQSDK 531
           R + P S++  C YC  G       R    +  ++P++C +C++ ++ +  L +H     
Sbjct: 154 RPQAPSSSAFRCPYCK-GKFRTSAERERHLHILHRPWKCGLCSFGSSQEEEL-LHHSLTA 211

Query: 532 HLAN---LQGFQAGPGGQGSP-------------------PEASLPPS---AGDKEPKTK 566
           H A    L    A P  Q  P                   PE    P+   A  +EP   
Sbjct: 212 HGAPERPLAATSAAPPPQPQPQPPPQPEPRSVPQPEPEPEPEREATPTPAPAAPEEPPAP 271

Query: 567 SSWQCKVCSYETNISRNLRIHMTSEK------------------HMQNVLMLHQGLPLGL 608
             ++C+VC      S  L+ HM   K                   ++N + +H    LG 
Sbjct: 272 PEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHAS-KLG- 329

Query: 609 PPGLMGPGPPPPPGATPTSPPEL----FQYFGPQALGQP 643
              L  PGP   P   P  PP+L    ++  GP  L  P
Sbjct: 330 --PLRAPGPASGPARAP-QPPDLGLLAYEPLGPALLLAP 365



 Score = 34.7 bits (78), Expect = 1.3
 Identities = 44/161 (27%), Positives = 55/161 (34%), Gaps = 12/161 (7%)

Query: 2405 AGPGRPLPQRPMPDQTNTSTAGTTDPVPGPPTEPLGDKVSSERKPV--AGPTSSSNDALK 2462
            AGPG P P+ P P Q  ++      P P P T   G   SS R P   AGP S    A  
Sbjct: 556  AGPGPP-PEPPPPSQRGSAPQSGAKPSPQPATWVEG--ASSPRPPSSGAGPGSRRKPASP 612

Query: 2463 NLKALKTTVPALLGGQFLPFPLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNPMI 2522
                   T+    GG+  P  L    G    A  G  L    F         L  ++  +
Sbjct: 613  G-----RTLRNGRGGEAEPLDLSLRAGPGGEAGPGGALHRCLFCPFATGAPELMALHLQV 667

Query: 2523 --PQTLIGLLPNALLQPPPQPPEPTATAPPKPPELPAPGEG 2561
               +   G  P      PP    P+   PP P +    G G
Sbjct: 668  HHSRRARGRRPPQADASPPYARVPSGETPPSPSQEGEEGSG 708



 Score = 32.7 bits (73), Expect = 5.0
 Identities = 45/188 (23%), Positives = 65/188 (34%), Gaps = 38/188 (20%)

Query: 569 WQCKVCSYETNISRNLRIHMTSEKHMQNVLMLHQGLPLGLPPGLMGPGPPPPPGATPTSP 628
           ++C  C Y    S +L+ H+      Q                  G GP PPP   P S 
Sbjct: 526 YKCPHCDYAGTQSGSLKYHLQRHHREQR----------------SGAGPGPPPEPPPPSQ 569

Query: 629 PELFQYFGPQALGQPQTPLAGPGLRPDKPLEAQLLLNGFHHVGAPARKFPTSAPGSLSPD 688
                  G +   QP T + G    P  P             G  +R+ P S PG    +
Sbjct: 570 RGSAPQSGAKPSPQPATWVEGAS-SPRPPSSG---------AGPGSRRKPAS-PGRTLRN 618

Query: 689 AHLPPSQLLGSSSDSLPTSPPPDDSLSLKVFRCLVCQAFSTDSLELLLYHCSI------- 741
                ++ L     SL   P  +      + RCL C  F+T + EL+  H  +       
Sbjct: 619 GRGGEAEPLDL---SLRAGPGGEAGPGGALHRCLFC-PFATGAPELMALHLQVHHSRRAR 674

Query: 742 GRSLPEAE 749
           GR  P+A+
Sbjct: 675 GRRPPQAD 682


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
          Length = 816

 Score = 64.7 bits (156), Expect = 1e-09
 Identities = 85/278 (30%), Positives = 104/278 (37%), Gaps = 60/278 (21%)

Query: 2327 PAPEAPPALK---APPATTPA-------------------SMPLGAAPTLPRLAPVLLSG 2364
            P+P APP+L+   +PPAT P+                   S PL    T P  AP  L+ 
Sbjct: 304  PSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALAL 363

Query: 2365 PAL-------AQPPLGNLA-PFNSGPAASSGLLGLATSVLPTTTVVQT--AGPGRP--LP 2412
            P L       A PPL  LA P    P A +  L  A    P +  VQ   + P  P   P
Sbjct: 364  PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSP 423

Query: 2413 QRPMPDQTNTSTAGTTDPVPGPPTEPLGDKVS-SERKPVAGPTSSSNDALKNLKALKTTV 2471
                P Q   S A    P+  PP+ P    +S S   P   P   +   L+  K      
Sbjct: 424  SATPPSQAPPSLA--APPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAP 481

Query: 2472 PALLGGQFLPFPLPPAG--GTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNPMI--PQTLI 2527
            PAL        P PPA   G AP   F P                  PM+P+   P    
Sbjct: 482  PALATPPLQALPSPPASFPGQAP---FSPSAS--------------LPMSPLATPPPQAP 524

Query: 2528 GLLPNALLQPPPQPP-EPTATAPPKPPELPAPGEGEAG 2564
             +L   LLQ PP PP  PT  AP +PP  P P    +G
Sbjct: 525  PVLAAPLLQVPPSPPASPTLQAPRRPP-TPGPDTSVSG 561



 Score = 55.1 bits (131), Expect = 9e-07
 Identities = 104/409 (25%), Positives = 142/409 (34%), Gaps = 75/409 (18%)

Query: 2327 PAPEAPPALKAPPA----TTPASMPLGAAPTLPRLAPVLLSGP-------------ALAQ 2369
            P  +APP+L APP     + PAS P+  + T P  AP  L+ P             ALA 
Sbjct: 427  PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALAT 486

Query: 2370 PPLGNL----------APFNSGPAASSGLLGLATSVLPTTTVVQTAGPGRPLPQRPMPDQ 2419
            PPL  L          APF+  P+AS  +  LAT   P       A P   +P  P P  
Sbjct: 487  PPLQALPSPPASFPGQAPFS--PSASLPMSPLATP--PPQAPPVLAAPLLQVP--PSPPA 540

Query: 2420 TNTSTAGTTDPVPGPPTEPLGDKVSSERKPVAGPTSSSNDALKNLKALKTTVPALLGGQF 2479
            + T  A    P PGP T   G +++    P   P  S + +            + L G  
Sbjct: 541  SPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPS------------STLSG-- 586

Query: 2480 LPFPLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNPMIPQTLIGLLPNALLQPPP 2539
                 P   G +  A   P+    Y     G + G     P  P   +     A     P
Sbjct: 587  -----PDLAGHSSSATSTPEELRGYDS---GPEGGAAASPP--PDAELAACHPAAWSRGP 636

Query: 2540 QPPEPTATAPPKP-PELPAPGEGEAGEVDELLTGSTGISTVDVTH-RYLCRQCKMAFD-G 2596
             PP     AP  P P  PA G G A           G+ T+  T           A D G
Sbjct: 637  APPLAFRGAPGAPLPWPPATGPGSA----------DGLCTIYETEGPESATPAPGALDPG 686

Query: 2597 EAPATAHQRSFCFFGRGSGGSMPPPLR---VPICTYHCLACEVLLSGREALASHLRSSAH 2653
             +P T+  ++    G G+    P   R   +P+        + LLS    LA+     A 
Sbjct: 687  PSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAA--AEGAA 744

Query: 2654 RRKAAPPQGGPPISITNAATAASAAVAFAKEEARLPHTDSNPKTTTTST 2702
                  P G     +T  A AA +     +    L   D +  + T+ T
Sbjct: 745  GGSGGGPGGAEGGGVTGGARAALSDAELGRWAELLSPLDESRASITSVT 793



 Score = 46.6 bits (109), Expect = 3e-04
 Identities = 50/180 (27%), Positives = 63/180 (35%), Gaps = 62/180 (34%)

Query: 2054 TPGGVPSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAP---------AFPYPT 2104
            +P   P P   PP  A P  L K                P  +AP         A P P 
Sbjct: 453  SPSATPPPQAPPPLAAPPLQLAK----------------PPPQAPPALATPPLQALPSPP 496

Query: 2105 ATLASGPQPFLP----PGKEATTPTPEPP----LPLL--PPPPPSEE--EGPEEPPKASP 2152
            A+   G  PF P    P     TP P+ P     PLL  PP PP+    + P  PP   P
Sbjct: 497  ASF-PGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGP 555

Query: 2153 E----------------------SEACSLSAGDLSDSSASSLAEPESPGAGGTSGGPGGG 2190
            +                      S + +LS  DL+  S+S+ + PE     G   GP GG
Sbjct: 556  DTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEE--LRGYDSGPEGG 613



 Score = 46.2 bits (108), Expect = 4e-04
 Identities = 82/333 (24%), Positives = 111/333 (33%), Gaps = 92/333 (27%)

Query: 2329 PEAPPALKAPPATTPASMP-LGAAPTL---------------------PRLAPVLLSGPA 2366
            P  P + + PP  TPA++  LGAA  +                     PR  P   S P 
Sbjct: 27   PRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRPP 86

Query: 2367 LA-----QPPLGNLAPFNSGPAASSGLLGLATSVLPT----------TTVVQ---TAGPG 2408
             +      PP  N +P   GP +S G     T   P            TV +   T  P 
Sbjct: 87   ASGRGERAPPAKNTSP---GPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPK 143

Query: 2409 R-------------PLPQRPMPDQTNTSTAGTTD---PVPGPPTEPLGDKVSSERKPVAG 2452
            R             P P  P P     S A  T+   P P P   P        R P  G
Sbjct: 144  RSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARP--------RPPTEG 195

Query: 2453 PTSSSNDALKNLKALKTTV----PALLGGQFLPFPLPPAGGTAP---PAVFGPQLQGAYF 2505
            P  S + A ++     +      P+  GG   P     +    P   PA  GP  +G   
Sbjct: 196  PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPR 255

Query: 2506 QQLYGMK---KGLFPMNPMIPQTL---------IGLLPNALLQPPPQPPEPTATAPPKPP 2553
               +  +   KGL  + P  PQ           +G L ++ L  P     P+ +APP   
Sbjct: 256  APAHPSQPKPKGLQALRP--PQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQ 313

Query: 2554 ELPAPGEGEAGEVDELLTGSTGISTVDVTHRYL 2586
             LP+P      +     T S G  T+  TH +L
Sbjct: 314  TLPSPPATPPSQA----TTSLGSPTLQATHSFL 342



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 46/153 (30%), Positives = 60/153 (39%), Gaps = 31/153 (20%)

Query: 1455 PFLSPPPPPLDLHRFPAPLFTPPVLPPFPLVPESLLKLQQQQLLLPFYLHDLKVGPKLTL 1514
            PF  PP PP+      AP F+PP  PP  + P +    Q    L       L+V P    
Sbjct: 400  PFSPPPSPPVQ-----AP-FSPPASPP--VSPSATPPSQAPPSLAA---PPLQVPP---- 444

Query: 1515 AGPAPVLSLPAATPPPPPQPPKA----ELAEREWERPPMAKEGNEAGPSSPPDPLPNEAA 1570
            + PA     P+ATPPP   PP A    +LA+   + PP           SPP   P +A 
Sbjct: 445  SPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAP 504

Query: 1571 RTAAKALLENFGFELVIQYNEGKQAVPPPPTPP 1603
             + + +L                 A PPP  PP
Sbjct: 505  FSPSASL------------PMSPLATPPPQAPP 525



 Score = 43.1 bits (100), Expect = 0.004
 Identities = 68/267 (25%), Positives = 88/267 (32%), Gaps = 71/267 (26%)

Query: 2327 PAPEAPPAL-----KAP-----------PATTPASMPLGAAPTLPRLAPVLLSGPALAQP 2370
            P+P+AP AL     +AP           P + PAS P+  + T P  AP  L+ P L  P
Sbjct: 384  PSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP 443

Query: 2371 PLGNLAPFNSGPAASSGLLGLATSVLPTTTVVQTAGP----GRPLPQRPMPDQTNTSTAG 2426
            P          P AS  +   AT   P       A P     +P PQ P    T    A 
Sbjct: 444  P---------SPPASPPMSPSATP--PPQAPPPLAAPPLQLAKPPPQAPPALATPPLQAL 492

Query: 2427 TTDPVPGPPTEPLGDKVSSERKPVAGPTSSSNDALKNLKALKTTVPALLGGQFLPFPLPP 2486
             + P   P   P     S    P+A P   +              P +L    L  P   
Sbjct: 493  PSPPASFPGQAPFSPSASLPMSPLATPPPQA--------------PPVLAAPLLQVP--- 535

Query: 2487 AGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNPMI--PQTLIG--LLPNALLQPPPQPP 2542
                +PPA   P LQ               P  P    P T +    L  AL   PP PP
Sbjct: 536  ---PSPPA--SPTLQA--------------PRRPPTPGPDTSVSGPRLTLALAPGPPPPP 576

Query: 2543 EPTATAPPKPPELPAPGEGEAGEVDEL 2569
              + ++    P+L           +EL
Sbjct: 577  SRSPSSTLSGPDLAGHSSSATSTPEEL 603



 Score = 42.7 bits (99), Expect = 0.005
 Identities = 38/116 (32%), Positives = 46/116 (39%), Gaps = 16/116 (13%)

Query: 605 PLGLPPGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRPDKPLEAQLLL 664
           PL  PP    P    PP   P SPP             P +PLA P  +    L   LL 
Sbjct: 349 PLATPPPQAPPALALPPLQAPPSPPA----------SPPLSPLATPSPQAPNALAVHLLQ 398

Query: 665 NGFHHVGAPARKFPTSAPGS--LSPDAHLPPSQL---LGSSSDSLPTSPPPDDSLS 715
             F    +P  + P S P S  +SP A  PPSQ    L +    +P SPP    +S
Sbjct: 399 APFSPPPSPPVQAPFSPPASPPVSPSA-TPPSQAPPSLAAPPLQVPPSPPASPPMS 453



 Score = 41.6 bits (96), Expect = 0.011
 Identities = 36/135 (26%), Positives = 50/135 (37%), Gaps = 13/135 (9%)

Query: 2058 VPSPAVKPPATATPA----SLPKFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQP 2113
            +PSP   PP+ AT +    +L   +  L           P +  PA   P       P P
Sbjct: 315  LPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-P 373

Query: 2114 FLPPGKEATTPTPEPPLPL--------LPPPPPSEEEGPEEPPKASPESEACSLSAGDLS 2165
              PP     TP+P+ P  L          PPP    + P  PP + P S + +  +    
Sbjct: 374  ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 433

Query: 2166 DSSASSLAEPESPGA 2180
              +A  L  P SP A
Sbjct: 434  SLAAPPLQVPPSPPA 448



 Score = 40.4 bits (93), Expect = 0.024
 Identities = 39/123 (31%), Positives = 45/123 (36%), Gaps = 19/123 (15%)

Query: 605 PLGLPPGLMGPG---PPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRPDKPLEAQ 661
           P   PP L  P    PP PP + P SP        P  L  P   LA P   P  P    
Sbjct: 428 PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKP--PPQAP--PA 483

Query: 662 LLLNGFHHVGAPARKFPTSAPGSLSPDAHLPPSQL----------LGSSSDSLPTSPPPD 711
           L       + +P   FP  AP   SP A LP S L          L +    +P SPP  
Sbjct: 484 LATPPLQALPSPPASFPGQAP--FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPAS 541

Query: 712 DSL 714
            +L
Sbjct: 542 PTL 544



 Score = 40.0 bits (92), Expect = 0.031
 Identities = 109/465 (23%), Positives = 149/465 (32%), Gaps = 96/465 (20%)

Query: 1218 LSPLEGPNLTP---EASP--DPLPEPPLASVEVPDKPSGSPGQPPS--PAPSPVPEPDAQ 1270
            L  L  P +TP   +A+P   PL   PLA+      PS  P  PPS    PSP   P +Q
Sbjct: 268  LQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPS--PSAPPSLQTLPSPPATPPSQ 325

Query: 1271 AEDVAPPPTMAEEEEGTTGELRSAEPAPADSRHPLTYRKTTNFALDKFL----DPARPYK 1326
            A      PT+    + T   L S   +P  +  P   +     AL         PA P  
Sbjct: 326  ATTSLGSPTL----QATHSFLPSPPLSPLATPPP---QAPPALALPPLQAPPSPPASPPL 378

Query: 1327 CTVCKESFTQKNILLVHYNSVSHLHKMKKAAIDPSAPARGEAGAPPTTTAATDKPFKCTV 1386
              +   S    N L VH                P +P      +P  T  +   P     
Sbjct: 379  SPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP----- 433

Query: 1387 CRVSYNQSSTLEIHMRSVLHQTRSRGTKTDSKIEGPERSQEEPKEGETEGEVGTEKKGPD 1446
                     +L      V     +    + S    P   Q  P       ++   K  P 
Sbjct: 434  ---------SLAAPPLQVPPSPPASPPMSPSATPPP---QAPPPLAAPPLQLA--KPPPQ 479

Query: 1447 TSGFISGLPFLSPPPPPLDLHRFP-------------APLFTPPVLPPFPLVPESLLKLQ 1493
                ++  P  + P PP     FP             +PL TPP   P P++   LL++ 
Sbjct: 480  APPALATPPLQALPSPPAS---FPGQAPFSPSASLPMSPLATPPPQAP-PVLAAPLLQVP 535

Query: 1494 QQQLLLPFYLHDLKV---GPKLTLAGPAPVLSLPAATPPPPPQPPKAELA-------ERE 1543
                  P      +    GP  +++GP   L+L    PPPP + P + L+          
Sbjct: 536  PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSS 595

Query: 1544 WERPPMAKEGNEAGP------SSPPD--------------PLPNEAARTAAKALLE---- 1579
                P    G ++GP      S PPD              P P  A R A  A L     
Sbjct: 596  ATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPA 655

Query: 1580 ----NFGFELVIQYNEGKQAVPPPP--TPPPPEALGGGDKLACGA 1618
                +      I   EG ++  P P    P P     G K A GA
Sbjct: 656  TGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGA 700



 Score = 40.0 bits (92), Expect = 0.031
 Identities = 36/129 (27%), Positives = 46/129 (35%), Gaps = 11/129 (8%)

Query: 2049 GQFRSTPGGVPSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAFPYPTATLA 2108
            G   S+P   PSP+  PP+ + P SL                  P +   +   PT    
Sbjct: 288  GPLSSSPLATPSPSA-PPSPSAPPSLQTL--------PSPPATPPSQATTSLGSPTLQAT 338

Query: 2109 SGPQPFLPPGKEATTPTPEPPLPLLPP--PPPSEEEGPEEPPKASPESEACSLSAGDLSD 2166
                P  P    AT P   PP   LPP   PPS    P   P A+P  +A +  A  L  
Sbjct: 339  HSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ 398

Query: 2167 SSASSLAEP 2175
            +  S    P
Sbjct: 399  APFSPPPSP 407



 Score = 39.3 bits (90), Expect = 0.053
 Identities = 30/99 (30%), Positives = 41/99 (41%), Gaps = 13/99 (13%)

Query: 2059 PSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQPFLPPG 2118
            PSP V+ P +  PAS P                 P +  P+   P   +   P P  PP 
Sbjct: 405  PSPPVQAPFSP-PASPPV----------SPSATPPSQAPPSLAAPPLQVPPSP-PASPPM 452

Query: 2119 KEATTPTPEPPLPLLPPPPPSEEEGPEEPPK-ASPESEA 2156
              + TP P+ P PL  PP    +  P+ PP  A+P  +A
Sbjct: 453  SPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQA 491



 Score = 38.9 bits (89), Expect = 0.070
 Identities = 75/292 (25%), Positives = 92/292 (31%), Gaps = 72/292 (24%)

Query: 1453 GLPFLSPP---PPPLDLHRF-----PAPLFTP-PVLPPFPLVPESLLKLQQQQLLLPFYL 1503
            GL  L PP   PP  D          +PL TP P  PP P  P SL  L       P   
Sbjct: 267  GLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQA 326

Query: 1504 HDLKVGPKLTLAG---PAPVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPSS 1560
                  P L       P+P LS P ATPPP   P    LA    + PP         P +
Sbjct: 327  TTSLGSPTLQATHSFLPSPPLS-PLATPPPQAPPA---LALPPLQAPPSPPASPPLSPLA 382

Query: 1561 PPDPLPNEAARTAAKALLENFGFELVIQYNEGKQAVPPPPTPP--PPEALGGGDKLACGA 1618
             P P   +A    A  LL+                  PPP+PP   P +      ++  A
Sbjct: 383  TPSP---QAPNALAVHLLQ--------------APFSPPPSPPVQAPFSPPASPPVSPSA 425

Query: 1619 CGKLFSNMLILKTHEEHVHRRFLPFEALSRYAAQFRKSYDSLYPPLAEPPKPPDGSLDSP 1678
                                   P +A    AA          PPL  PP PP     SP
Sbjct: 426  TP---------------------PSQAPPSLAA----------PPLQVPPSPPASPPMSP 454

Query: 1679 V----PHLGPPFLVPEPEAGGTRAPEERSRAGGHWPIEEEESSRGNLPPLVP 1726
                 P   PP   P  +    + P +   A    P++   S   + P   P
Sbjct: 455  SATPPPQAPPPLAAPPLQL--AKPPPQAPPALATPPLQALPSPPASFPGQAP 504



 Score = 38.1 bits (87), Expect = 0.12
 Identities = 40/133 (30%), Positives = 48/133 (36%), Gaps = 28/133 (21%)

Query: 2061 PAVKPPAT-ATPASLPKFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQPFLPPGK 2119
            P V PP   A PA  P  +  L           P   AP  P    +L + P P   P  
Sbjct: 274  PQVTPPRKDAAPALGPLSSSPLA---------TPSPSAPPSPSAPPSLQTLPSPPATPPS 324

Query: 2120 EATT----PT--------PEPPLPLLPPPPPSEEEGPEEPPKASPESEACSLSAGDLSDS 2167
            +ATT    PT        P PPL  L  PPP        PP  +P S   S     L+  
Sbjct: 325  QATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATP 384

Query: 2168 SASSLAEPESPGA 2180
            S      P++P A
Sbjct: 385  S------PQAPNA 391



 Score = 36.2 bits (82), Expect = 0.45
 Identities = 29/95 (30%), Positives = 39/95 (41%), Gaps = 18/95 (18%)

Query: 1213 SLYFLLSPLEGPNLTPEASP-DPLPEPPLASVEVPDKPSGSPGQ--------PPSPAPSP 1263
            +++ L +P   P   P  +P  P   PP++    P  PS +P          PPSP  SP
Sbjct: 393  AVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATP--PSQAPPSLAAPPLQVPPSPPASP 450

Query: 1264 VPEPDAQAEDVAPPPTMAEEEEGTTGELRSAEPAP 1298
               P A     APPP  A         L+ A+P P
Sbjct: 451  PMSPSATPPPQAPPPLAAP-------PLQLAKPPP 478



 Score = 35.4 bits (80), Expect = 0.77
 Identities = 81/365 (22%), Positives = 113/365 (30%), Gaps = 63/365 (17%)

Query: 72  EIGEPQEGPDCGHFPPNDPGVEKDKEQEEEEEGLPPMDLSNHLFFTAGGEAYLVAKLSLP 131
           E+G P+  P     PP + G  K      E     P   +       GG     ++    
Sbjct: 177 EVGLPRPAPSARPRPPTE-GPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS 235

Query: 132 GGSELLLPKGFPWGEAGIKEEPSLPFLAYPPPSHLTALHIQHGFDPIQGFSSS-DQILSH 190
             + L  P        G    P+ P  + P P  L AL       P +  + +   + S 
Sbjct: 236 SATPLSSPARSGPSARGTPRAPAHP--SQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS 293

Query: 191 DTSAPSPAACEERHGAFWSYQLAPNPPGDPKDGPMGNSGGNHVAVFWLCLLCRLGFSKPQ 250
             + PSP+A      A  S Q  P+PP  P      + G                   P 
Sbjct: 294 PLATPSPSA-PPSPSAPPSLQTLPSPPATPPSQATTSLGS------------------PT 334

Query: 251 AFMDHTQSHGVKLTPAQYQGLSGSPAVLQEGDEGCKALISFLEP-KLPARPSSDIPLDNS 309
               H+      L+P         PA+              L P + P  P +  PL   
Sbjct: 335 LQATHSFLPSPPLSPLATPPPQAPPALA-------------LPPLQAPPSPPASPPLSPL 381

Query: 310 STVNMEANVAQTEDGPPEAEVQALILLDEEVMALSPPSPPTATWDPSPTQAKESPVAAGE 369
           +T + +A         P A    L+    +     PPSPP         QA  SP A+  
Sbjct: 382 ATPSPQA---------PNALAVHLL----QAPFSPPPSPPV--------QAPFSPPASPP 420

Query: 370 AGPDWFPEGQEEDGGLCPPLNQSSPTSKEGGTLPAPVGSPEDPSDPP---QPYRLADDYT 426
             P   P  Q       PPL    P S       +P  +P   + PP    P +LA    
Sbjct: 421 VSPSATPPSQAPPSLAAPPL--QVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPP 478

Query: 427 PAPAA 431
            AP A
Sbjct: 479 QAPPA 483



 Score = 33.5 bits (75), Expect = 2.9
 Identities = 52/185 (28%), Positives = 67/185 (36%), Gaps = 47/185 (25%)

Query: 1518 APVLSLPAA-----TPPPPPQP-PKAELAEREWERPPMAKEGNEA-GP-SSPPDPLPNEA 1569
            +P  S P+A      P  P QP PK   A R  +  P  K+   A GP SS P   P+ +
Sbjct: 242  SPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPS 301

Query: 1570 ARTAAKALLENFGFELVIQYNEGKQAVPPPPTPPPPEALGGGDKLACGACGKLFSNMLIL 1629
            A  +  A                 Q +P PP  PP +A                 +  + 
Sbjct: 302  APPSPSA-------------PPSLQTLPSPPATPPSQATTS------------LGSPTLQ 336

Query: 1630 KTHEEHVHRRFLPFEALSRYAAQFRKSYDSL-YPPLAEPPKPPDGSLDSPVPHLGPPFLV 1688
             TH       FLP   LS  A    ++  +L  PPL  PP PP        P L  P   
Sbjct: 337  ATHS------FLPSPPLSPLATPPPQAPPALALPPLQAPPSPPAS------PPLS-PLAT 383

Query: 1689 PEPEA 1693
            P P+A
Sbjct: 384  PSPQA 388



 Score = 33.1 bits (74), Expect = 3.8
 Identities = 47/161 (29%), Positives = 55/161 (34%), Gaps = 29/161 (18%)

Query: 2053 STPGGVPSPAVKPPATATPASLPKFNLLLGK---VDDGTGREAPKREAPAFPYPTATLAS 2109
            ++PG V SP  +   T  P  L +  L +     V  G   EAPKR A +      T  S
Sbjct: 100  TSPGPVSSPG-RASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDT--S 156

Query: 2110 GPQPFLPP----------GKEATTPTPEPPLPLLPPPP--------PSEEEGPEEPPKAS 2151
            GP P  P           G E   P P P     PP           SE    E  P A 
Sbjct: 157  GPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAAR 216

Query: 2152 PESEA---CSLSAGDLSDSSASSLAEP--ESPGAGGTSGGP 2187
                A       A     SSA+ L+ P    P A GT   P
Sbjct: 217  RRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAP 257



 Score = 32.7 bits (73), Expect = 5.0
 Identities = 48/183 (26%), Positives = 57/183 (31%), Gaps = 42/183 (22%)

Query: 548 SPPEASLPPSAGDKEPKTKSSWQCKVCSYETNISRNLRIHMTSEKHMQNVLMLHQ-GLPL 606
           +PP  +LPP      P                 S  L    T      N L +H    P 
Sbjct: 357 APPALALPPLQAPPSPPA---------------SPPLSPLATPSPQAPNALAVHLLQAPF 401

Query: 607 GLPPGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQ-----TPLAGPGLRPD------ 655
             PP      P  PP + P SP        P +L  P      +P A P + P       
Sbjct: 402 SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 461

Query: 656 --KPLEAQLLLNGFHHVGAPARKFPTSAPGSLSPDAHLPPSQLLGSSSDSLPTSPPPDDS 713
              PL A  L            K P  AP +L+     PP Q L S   S P   P   S
Sbjct: 462 APPPLAAPPL---------QLAKPPPQAPPALA----TPPLQALPSPPASFPGQAPFSPS 508

Query: 714 LSL 716
            SL
Sbjct: 509 ASL 511



 Score = 32.7 bits (73), Expect = 5.0
 Identities = 28/101 (27%), Positives = 39/101 (38%), Gaps = 19/101 (18%)

Query: 2059 PSPAVKPPAT--ATPASLPKFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQPFLP 2116
            PSP   PP +  ATP+      L +  +           +AP  P P+  + +   PF P
Sbjct: 370  PSPPASPPLSPLATPSPQAPNALAVHLL-----------QAPFSPPPSPPVQA---PFSP 415

Query: 2117 PGKEATTPTPEPPL---PLLPPPPPSEEEGPEEPPKASPES 2154
            P     +P+  PP    P L  PP      P   P  SP +
Sbjct: 416  PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSA 456



 Score = 32.7 bits (73), Expect = 5.0
 Identities = 51/195 (26%), Positives = 65/195 (33%), Gaps = 61/195 (31%)

Query: 2060 SPAVKPPATATPASLPKFNLLLGKVDDGTGR--------EAPKREAPAFPYPTATLAS-- 2109
            +P   PP + +P+S      L G     T            P+  A A P P A LA+  
Sbjct: 569  APGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACH 628

Query: 2110 ------GPQPFLPPGKEATTPTPEPPLPLLPPPPPS---------EEEGPEEP------- 2147
                  GP P L     A    P  PLP  P   P          E EGPE         
Sbjct: 629  PAAWSRGPAPPL-----AFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGAL 683

Query: 2148 -PKASPESEACSLSAGDLSDSSASSLAEP---ESP--------------------GAGGT 2183
             P  SP +     +AG  + +S+ S  +    E P                     A G 
Sbjct: 684  DPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGA 743

Query: 2184 SGGPGGGTGVPDGMG 2198
            +GG GGG G  +G G
Sbjct: 744  AGGSGGGPGGAEGGG 758


>gi|148277064 cut-like homeobox 1 isoform a [Homo sapiens]
          Length = 1505

 Score = 64.3 bits (155), Expect = 2e-09
 Identities = 65/242 (26%), Positives = 94/242 (38%), Gaps = 27/242 (11%)

Query: 1964 LKRKHEDGSLSP------TGSEAGGGGEGEPPRD-KRLRTTILPEQLEILYRWYMQDSNP 2016
            +KR+H   S S        G+E   G   +P    K+ R  + PE+ E L R Y Q   P
Sbjct: 1210 MKRRHSSVSDSQPCEPPSVGTEYSQGASPQPQHQLKKPRVVLAPEEKEALKRAYQQKPYP 1269

Query: 2017 TRKMLDCISEEVGLKKRVVQVWFQNTRARERKGQF-RSTPGGVPSPAVKPPATATPASLP 2075
            + K ++ ++ ++ LK   V  WF N R+R R+  F      G    A    A+ +P++  
Sbjct: 1270 SPKTIEDLATQLNLKTSTVINWFHNYRSRIRRELFIEEIQAGSQGQA---GASDSPSA-- 1324

Query: 2076 KFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQPFLPPGKEATTPTPEPPLPL-LP 2134
                        +GR AP  E  +     AT   G      P  +      E P P    
Sbjct: 1325 -----------RSGRAAPSSEGDSCDGVEATEGPGSADTEEPKSQGEAEREEVPRPAEQT 1373

Query: 2135 PPPPSEEEGPEEPPKASPESEACSLSAGDLSDSSASSLAEPESPGAGGTS--GGPGGGTG 2192
             PPPS   GP++      E           S +SA++ A P +P    TS    PG G  
Sbjct: 1374 EPPPSGTPGPDDARDDDHEGGPVEGPGPLPSPASATATAAPAAPEDAATSAAAAPGEGPA 1433

Query: 2193 VP 2194
             P
Sbjct: 1434 AP 1435



 Score = 50.4 bits (119), Expect = 2e-05
 Identities = 54/200 (27%), Positives = 80/200 (40%), Gaps = 23/200 (11%)

Query: 1740 QTQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARK----NACEGGSMP 1795
            + +AL+  ++   YP    +E LA+ L L +  V+ WF N R + R+       + GS  
Sbjct: 1255 EKEALKRAYQQKPYPSPKTIEDLATQLNLKTSTVINWFHNYRSRIRRELFIEEIQAGSQG 1314

Query: 1796 TGGGTGGASGCRRCHATFSCVFELVRHLKKCYDDQTLEEEEEEAERGEEEEEVEEEEVEE 1855
              G +   S  R   A  S   +    ++      + + EE +++   E EEV       
Sbjct: 1315 QAGASDSPS-ARSGRAAPSSEGDSCDGVEATEGPGSADTEEPKSQGEAEREEVPR---PA 1370

Query: 1856 EQGLEPPAGPEGPLPEPPDGEELSQAEATKAGGKEPEEKATPSPSPAHTCDQCAISFSSQ 1915
            EQ   PP+G  GP     D  E         GG  P E   P PSPA +    A   + +
Sbjct: 1371 EQTEPPPSGTPGPDDARDDDHE---------GG--PVEGPGPLPSPA-SATATAAPAAPE 1418

Query: 1916 DLLTSHRRLHFLPSLQPSAP 1935
            D  TS       P   P+AP
Sbjct: 1419 DAATSAAA---APGEGPAAP 1435



 Score = 33.1 bits (74), Expect = 3.8
 Identities = 26/94 (27%), Positives = 38/94 (40%), Gaps = 6/94 (6%)

Query: 1220 PLEGPNLTPEASPDPLPEPPLASVEVPDKPSGSPGQPPSPAPSPVPEPDAQAEDVAP-PP 1278
            P+EGP   P  +       P A  +     + +PG+ P+ APS  P P   +   AP  P
Sbjct: 1395 PVEGPGPLPSPASATATAAPAAPEDAATSAAAAPGEGPA-APSSAPPPSNSSSSSAPRRP 1453

Query: 1279 TMAEEEEGTTGELRSAEPAPADSRHPLTYRKTTN 1312
            +  +   G    L  A  A     +PL  +K  N
Sbjct: 1454 SSLQSLFG----LPEAAGARDSRDNPLRKKKAAN 1483



 Score = 32.0 bits (71), Expect = 8.5
 Identities = 26/80 (32%), Positives = 31/80 (38%), Gaps = 13/80 (16%)

Query: 1527 TPPPPPQPPKAELAEREWERPPMAKEGNEAGPSSPPDPLPN--EAARTAAKALLENFGFE 1584
            T PPP   P  + A           + +E GP   P PLP+   A  TAA A  E+    
Sbjct: 1373 TEPPPSGTPGPDDAR---------DDDHEGGPVEGPGPLPSPASATATAAPAAPEDAATS 1423

Query: 1585 LVIQYNEGKQAVPPPPTPPP 1604
                  EG  A  P   PPP
Sbjct: 1424 AAAAPGEGPAA--PSSAPPP 1441


>gi|30023847 LIM homeobox protein 3 isoform a [Homo sapiens]
          Length = 397

 Score = 64.3 bits (155), Expect = 2e-09
 Identities = 66/227 (29%), Positives = 86/227 (37%), Gaps = 38/227 (16%)

Query: 1992 KRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQNTRARERK--- 2048
            KR RTTI  +QLE L   Y     P R + + +S E GL  RVVQVWFQN RA+E++   
Sbjct: 158  KRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKK 217

Query: 2049 -------GQF-----RSTPGGV---------------------PSPAVKPPATATPASLP 2075
                   GQ+     RS  G                       PS A   PA     SL 
Sbjct: 218  DAGRQRWGQYFRNMKRSRGGSKSDKDSVQEGQDSDAEVSFPDEPSLAEMGPANGLYGSLG 277

Query: 2076 KFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQPFLPPGKEA--TTPTPEPPLPLL 2133
            +    LG+     G  + +    A P     L  G    +PP   A  + P P+P L  L
Sbjct: 278  EPTQALGRPSGALGNFSLEHGGLAGPEQYRELRPGSPYGVPPSPAAPQSLPGPQPLLSSL 337

Query: 2134 PPPPPSEEEGPEEPPKASPESEACSLSAGDLSDSSASSLAEPESPGA 2180
              P  S    P   P   P     + +      S+ SS   P+ P +
Sbjct: 338  VYPDTSLGLVPSGAPGGPPPMRVLAGNGPSSDLSTGSSGGYPDFPAS 384



 Score = 55.5 bits (132), Expect = 7e-07
 Identities = 61/231 (26%), Positives = 88/231 (38%), Gaps = 47/231 (20%)

Query: 2200 RRYRTQMSSLQLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAKL 2259
            +R RT +++ QL+ +K+ Y     P     E L  E GL  RV+QVWFQN RAKEK+ K 
Sbjct: 158  KRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKK 217

Query: 2260 QG----------TAAGSTGGSSEGLLAAQRTDCPYCDVKYDFYVSCR---------GHL- 2299
                            S GGS     + Q       +V +    S           G L 
Sbjct: 218  DAGRQRWGQYFRNMKRSRGGSKSDKDSVQEGQDSDAEVSFPDEPSLAEMGPANGLYGSLG 277

Query: 2300 ---------------FSRQHLAKLKEAVRAQLKSESKCYDLAPAPEAPPALKAP------ 2338
                           FS +H          +L+  S  Y + P+P AP +L  P      
Sbjct: 278  EPTQALGRPSGALGNFSLEHGGLAGPEQYRELRPGSP-YGVPPSPAAPQSLPGPQPLLSS 336

Query: 2339 ---PATTPASMPLGAAPTLPRLAPVLLSGPA--LAQPPLGNLAPFNSGPAA 2384
               P T+   +P GA    P +  +  +GP+  L+    G    F + PA+
Sbjct: 337  LVYPDTSLGLVPSGAPGGPPPMRVLAGNGPSSDLSTGSSGGYPDFPASPAS 387



 Score = 45.8 bits (107), Expect = 6e-04
 Identities = 57/220 (25%), Positives = 81/220 (36%), Gaps = 36/220 (16%)

Query: 1733 RTKFTEFQTQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARKNACEGG 1792
            RT  T  Q + L+S + TS  P     E+L+S  GL  RVV VWFQN R K ++   + G
Sbjct: 161  RTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAG 220

Query: 1793 SMPTGGGTGGASGCRRCHATFSCVFELVRHLKKCYDDQTLEEEE-EEAERGEEEEEVEEE 1851
                G                    +  R++K+       +++  +E +  + E    +E
Sbjct: 221  RQRWG--------------------QYFRNMKRSRGGSKSDKDSVQEGQDSDAEVSFPDE 260

Query: 1852 EVEEEQGLEPPAGPEGPLPEP------PDGE--ELSQAEATKAGGKEPEEKATPS----- 1898
                E G  P  G  G L EP      P G     S      AG ++  E    S     
Sbjct: 261  PSLAEMG--PANGLYGSLGEPTQALGRPSGALGNFSLEHGGLAGPEQYRELRPGSPYGVP 318

Query: 1899 PSPAHTCDQCAISFSSQDLLTSHRRLHFLPSLQPSAPPQL 1938
            PSPA              L+     L  +PS  P  PP +
Sbjct: 319  PSPAAPQSLPGPQPLLSSLVYPDTSLGLVPSGAPGGPPPM 358


>gi|7657303 LIM homeobox protein 3 isoform b [Homo sapiens]
          Length = 402

 Score = 64.3 bits (155), Expect = 2e-09
 Identities = 66/227 (29%), Positives = 86/227 (37%), Gaps = 38/227 (16%)

Query: 1992 KRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQNTRARERK--- 2048
            KR RTTI  +QLE L   Y     P R + + +S E GL  RVVQVWFQN RA+E++   
Sbjct: 163  KRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKK 222

Query: 2049 -------GQF-----RSTPGGV---------------------PSPAVKPPATATPASLP 2075
                   GQ+     RS  G                       PS A   PA     SL 
Sbjct: 223  DAGRQRWGQYFRNMKRSRGGSKSDKDSVQEGQDSDAEVSFPDEPSLAEMGPANGLYGSLG 282

Query: 2076 KFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQPFLPPGKEA--TTPTPEPPLPLL 2133
            +    LG+     G  + +    A P     L  G    +PP   A  + P P+P L  L
Sbjct: 283  EPTQALGRPSGALGNFSLEHGGLAGPEQYRELRPGSPYGVPPSPAAPQSLPGPQPLLSSL 342

Query: 2134 PPPPPSEEEGPEEPPKASPESEACSLSAGDLSDSSASSLAEPESPGA 2180
              P  S    P   P   P     + +      S+ SS   P+ P +
Sbjct: 343  VYPDTSLGLVPSGAPGGPPPMRVLAGNGPSSDLSTGSSGGYPDFPAS 389



 Score = 55.5 bits (132), Expect = 7e-07
 Identities = 61/231 (26%), Positives = 88/231 (38%), Gaps = 47/231 (20%)

Query: 2200 RRYRTQMSSLQLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAKL 2259
            +R RT +++ QL+ +K+ Y     P     E L  E GL  RV+QVWFQN RAKEK+ K 
Sbjct: 163  KRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKK 222

Query: 2260 QG----------TAAGSTGGSSEGLLAAQRTDCPYCDVKYDFYVSCR---------GHL- 2299
                            S GGS     + Q       +V +    S           G L 
Sbjct: 223  DAGRQRWGQYFRNMKRSRGGSKSDKDSVQEGQDSDAEVSFPDEPSLAEMGPANGLYGSLG 282

Query: 2300 ---------------FSRQHLAKLKEAVRAQLKSESKCYDLAPAPEAPPALKAP------ 2338
                           FS +H          +L+  S  Y + P+P AP +L  P      
Sbjct: 283  EPTQALGRPSGALGNFSLEHGGLAGPEQYRELRPGSP-YGVPPSPAAPQSLPGPQPLLSS 341

Query: 2339 ---PATTPASMPLGAAPTLPRLAPVLLSGPA--LAQPPLGNLAPFNSGPAA 2384
               P T+   +P GA    P +  +  +GP+  L+    G    F + PA+
Sbjct: 342  LVYPDTSLGLVPSGAPGGPPPMRVLAGNGPSSDLSTGSSGGYPDFPASPAS 392



 Score = 45.8 bits (107), Expect = 6e-04
 Identities = 57/220 (25%), Positives = 81/220 (36%), Gaps = 36/220 (16%)

Query: 1733 RTKFTEFQTQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARKNACEGG 1792
            RT  T  Q + L+S + TS  P     E+L+S  GL  RVV VWFQN R K ++   + G
Sbjct: 166  RTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAG 225

Query: 1793 SMPTGGGTGGASGCRRCHATFSCVFELVRHLKKCYDDQTLEEEE-EEAERGEEEEEVEEE 1851
                G                    +  R++K+       +++  +E +  + E    +E
Sbjct: 226  RQRWG--------------------QYFRNMKRSRGGSKSDKDSVQEGQDSDAEVSFPDE 265

Query: 1852 EVEEEQGLEPPAGPEGPLPEP------PDGE--ELSQAEATKAGGKEPEEKATPS----- 1898
                E G  P  G  G L EP      P G     S      AG ++  E    S     
Sbjct: 266  PSLAEMG--PANGLYGSLGEPTQALGRPSGALGNFSLEHGGLAGPEQYRELRPGSPYGVP 323

Query: 1899 PSPAHTCDQCAISFSSQDLLTSHRRLHFLPSLQPSAPPQL 1938
            PSPA              L+     L  +PS  P  PP +
Sbjct: 324  PSPAAPQSLPGPQPLLSSLVYPDTSLGLVPSGAPGGPPPM 363


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 855

 Score = 63.2 bits (152), Expect = 3e-09
 Identities = 121/497 (24%), Positives = 172/497 (34%), Gaps = 73/497 (14%)

Query: 2094 KREAPAFPYPTATLASGPQPFLPPGKEATTPTPEPPLPLLPPP-------------PPSE 2140
            K +A A     A  A G     PPG      +P PP P+ P               P +E
Sbjct: 7    KAKAGAAARTPAARAPGLLTPRPPG------SPRPPPPVTPAALRVLGAAGAVGRKPLAE 60

Query: 2141 EEG-------PEEPPKASPESEACSLSAGDLSDSSASSLAEPESPGAGGTSGGP------ 2187
              G       PE  P+A P   A + S    S   AS   E  +P A  TS GP      
Sbjct: 61   RAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGE-RAPPAKNTSPGPVSSPGR 119

Query: 2188 GGGTGVPDGMGQRRYRTQMSSLQLKIMKACYEAYRTPTMQ---ECEVLGEEIGLPKRVIQ 2244
              GT  P  +GQ+  R  +S+ +        EA +   +      +  G   G P     
Sbjct: 120  ASGTTRPGPLGQKGLR--ISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTP----- 172

Query: 2245 VWFQNARAKEKKAKLQGTAAGSTGGSSEGLLAAQRTDCPYCDVKYDFYVSCRGHLFSRQH 2304
                 + A  ++++  GT  G     +        T+ P   V      S   H  +   
Sbjct: 173  -----SPAMARRSRAAGTEVG-LPRPAPSARPRPPTEGPRKSVS-----SASEHSTTEPS 221

Query: 2305 LA--KLKEAVRAQLKSESKCYDLAPAPEAPPALKAPPATTPASMPLGAAPTLPRLAPVLL 2362
             A  +   A     +  S+    +  P + PA   P A      P  A P+ P+   +  
Sbjct: 222  PAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAP--AHPSQPKPKGLQA 279

Query: 2363 SGPALAQPPLGNLAPFNSGPAASSGLLGLATSVLPTTTVVQTAGPGRPLPQRPMPDQTNT 2422
              P    PP  + AP   GP +SS L   + S       +Q+  P    P  P    +++
Sbjct: 280  LRPPQVTPPRKDAAP-ALGPLSSSPLATPSPS-----AALQSQAP----PTLPATPHSSS 329

Query: 2423 STAGTTDPVP-GPPTEPLGDKVSSERKPVAGPTSSSNDALKNLKALKTTVPALLGGQFLP 2481
             T     P+P  PP+      + +   P A P S +  +L +   L+ T   L      P
Sbjct: 330  LTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGS-PTLQATHSFLPSPPLSP 388

Query: 2482 FPLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNPMIPQTLIGLLPNALLQPPPQP 2541
               PP    APPA+  P LQ             L   +P  P  L   L  A   PPP P
Sbjct: 389  LATPPP--QAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP 446

Query: 2542 PEPTATAPP-KPPELPA 2557
            P     +PP  PP  P+
Sbjct: 447  PVQAPFSPPASPPVSPS 463



 Score = 62.4 bits (150), Expect = 6e-09
 Identities = 77/252 (30%), Positives = 91/252 (36%), Gaps = 57/252 (22%)

Query: 2327 PAPEAPPALKAPPATTPASMPLG--------AAPTLPR-LAPVLLSGPALAQPPLGNLAP 2377
            P P+APPAL  PP   P S P           +P  P  LA  LL  P    P     AP
Sbjct: 392  PPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAP 451

Query: 2378 FNSGPAASSGLLGLATSVLPTTTVVQTAGPGRPLPQRPMPDQTNTSTAGTTDPVPGPPTE 2437
            F+  P AS  +   AT   P+      A P  PL   P P  +   +   T P   PP  
Sbjct: 452  FS--PPASPPVSPSATP--PSQAPPSLAAP--PLQVPPSPPASPPMSPSATPPPQAPP-- 503

Query: 2438 PLGDKVSSERKPVAGPTSSSNDALKNLKALKTTVPALLGGQFLPFPLPPAG--GTAPPAV 2495
                       P+A P       L+  K      PAL        P PPA   G AP   
Sbjct: 504  -----------PLAAP------PLQLAKPPPQAPPALATPPLQALPSPPASFPGQAP--- 543

Query: 2496 FGPQLQGAYFQQLYGMKKGLFPMNPMI--PQTLIGLLPNALLQPPPQPP-EPTATAPPKP 2552
            F P                  PM+P+   P     +L   LLQ PP PP  PT  AP +P
Sbjct: 544  FSPSAS--------------LPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRP 589

Query: 2553 PELPAPGEGEAG 2564
            P  P P    +G
Sbjct: 590  P-TPGPDTSVSG 600



 Score = 55.1 bits (131), Expect = 9e-07
 Identities = 104/409 (25%), Positives = 142/409 (34%), Gaps = 75/409 (18%)

Query: 2327 PAPEAPPALKAPPA----TTPASMPLGAAPTLPRLAPVLLSGP-------------ALAQ 2369
            P  +APP+L APP     + PAS P+  + T P  AP  L+ P             ALA 
Sbjct: 466  PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALAT 525

Query: 2370 PPLGNL----------APFNSGPAASSGLLGLATSVLPTTTVVQTAGPGRPLPQRPMPDQ 2419
            PPL  L          APF+  P+AS  +  LAT   P       A P   +P  P P  
Sbjct: 526  PPLQALPSPPASFPGQAPFS--PSASLPMSPLATP--PPQAPPVLAAPLLQVP--PSPPA 579

Query: 2420 TNTSTAGTTDPVPGPPTEPLGDKVSSERKPVAGPTSSSNDALKNLKALKTTVPALLGGQF 2479
            + T  A    P PGP T   G +++    P   P  S + +            + L G  
Sbjct: 580  SPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPS------------STLSG-- 625

Query: 2480 LPFPLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNPMIPQTLIGLLPNALLQPPP 2539
                 P   G +  A   P+    Y     G + G     P  P   +     A     P
Sbjct: 626  -----PDLAGHSSSATSTPEELRGYDS---GPEGGAAASPP--PDAELAACHPAAWSRGP 675

Query: 2540 QPPEPTATAPPKP-PELPAPGEGEAGEVDELLTGSTGISTVDVTH-RYLCRQCKMAFD-G 2596
             PP     AP  P P  PA G G A           G+ T+  T           A D G
Sbjct: 676  APPLAFRGAPGAPLPWPPATGPGSA----------DGLCTIYETEGPESATPAPGALDPG 725

Query: 2597 EAPATAHQRSFCFFGRGSGGSMPPPLR---VPICTYHCLACEVLLSGREALASHLRSSAH 2653
             +P T+  ++    G G+    P   R   +P+        + LLS    LA+     A 
Sbjct: 726  PSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAA--AEGAA 783

Query: 2654 RRKAAPPQGGPPISITNAATAASAAVAFAKEEARLPHTDSNPKTTTTST 2702
                  P G     +T  A AA +     +    L   D +  + T+ T
Sbjct: 784  GGSGGGPGGAEGGGVTGGARAALSDAELGRWAELLSPLDESRASITSVT 832



 Score = 46.6 bits (109), Expect = 3e-04
 Identities = 50/180 (27%), Positives = 63/180 (35%), Gaps = 62/180 (34%)

Query: 2054 TPGGVPSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAP---------AFPYPT 2104
            +P   P P   PP  A P  L K                P  +AP         A P P 
Sbjct: 492  SPSATPPPQAPPPLAAPPLQLAK----------------PPPQAPPALATPPLQALPSPP 535

Query: 2105 ATLASGPQPFLP----PGKEATTPTPEPP----LPLL--PPPPPSEE--EGPEEPPKASP 2152
            A+   G  PF P    P     TP P+ P     PLL  PP PP+    + P  PP   P
Sbjct: 536  ASF-PGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGP 594

Query: 2153 E----------------------SEACSLSAGDLSDSSASSLAEPESPGAGGTSGGPGGG 2190
            +                      S + +LS  DL+  S+S+ + PE     G   GP GG
Sbjct: 595  DTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEE--LRGYDSGPEGG 652



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 46/153 (30%), Positives = 60/153 (39%), Gaps = 31/153 (20%)

Query: 1455 PFLSPPPPPLDLHRFPAPLFTPPVLPPFPLVPESLLKLQQQQLLLPFYLHDLKVGPKLTL 1514
            PF  PP PP+      AP F+PP  PP  + P +    Q    L       L+V P    
Sbjct: 439  PFSPPPSPPVQ-----AP-FSPPASPP--VSPSATPPSQAPPSLAA---PPLQVPP---- 483

Query: 1515 AGPAPVLSLPAATPPPPPQPPKA----ELAEREWERPPMAKEGNEAGPSSPPDPLPNEAA 1570
            + PA     P+ATPPP   PP A    +LA+   + PP           SPP   P +A 
Sbjct: 484  SPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAP 543

Query: 1571 RTAAKALLENFGFELVIQYNEGKQAVPPPPTPP 1603
             + + +L                 A PPP  PP
Sbjct: 544  FSPSASL------------PMSPLATPPPQAPP 564



 Score = 43.1 bits (100), Expect = 0.004
 Identities = 68/267 (25%), Positives = 88/267 (32%), Gaps = 71/267 (26%)

Query: 2327 PAPEAPPAL-----KAP-----------PATTPASMPLGAAPTLPRLAPVLLSGPALAQP 2370
            P+P+AP AL     +AP           P + PAS P+  + T P  AP  L+ P L  P
Sbjct: 423  PSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP 482

Query: 2371 PLGNLAPFNSGPAASSGLLGLATSVLPTTTVVQTAGP----GRPLPQRPMPDQTNTSTAG 2426
            P          P AS  +   AT   P       A P     +P PQ P    T    A 
Sbjct: 483  P---------SPPASPPMSPSATP--PPQAPPPLAAPPLQLAKPPPQAPPALATPPLQAL 531

Query: 2427 TTDPVPGPPTEPLGDKVSSERKPVAGPTSSSNDALKNLKALKTTVPALLGGQFLPFPLPP 2486
             + P   P   P     S    P+A P   +              P +L    L  P   
Sbjct: 532  PSPPASFPGQAPFSPSASLPMSPLATPPPQA--------------PPVLAAPLLQVP--- 574

Query: 2487 AGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNPMI--PQTLIG--LLPNALLQPPPQPP 2542
                +PPA   P LQ               P  P    P T +    L  AL   PP PP
Sbjct: 575  ---PSPPA--SPTLQA--------------PRRPPTPGPDTSVSGPRLTLALAPGPPPPP 615

Query: 2543 EPTATAPPKPPELPAPGEGEAGEVDEL 2569
              + ++    P+L           +EL
Sbjct: 616  SRSPSSTLSGPDLAGHSSSATSTPEEL 642



 Score = 42.7 bits (99), Expect = 0.005
 Identities = 38/116 (32%), Positives = 46/116 (39%), Gaps = 16/116 (13%)

Query: 605 PLGLPPGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRPDKPLEAQLLL 664
           PL  PP    P    PP   P SPP             P +PLA P  +    L   LL 
Sbjct: 388 PLATPPPQAPPALALPPLQAPPSPPA----------SPPLSPLATPSPQAPNALAVHLLQ 437

Query: 665 NGFHHVGAPARKFPTSAPGS--LSPDAHLPPSQL---LGSSSDSLPTSPPPDDSLS 715
             F    +P  + P S P S  +SP A  PPSQ    L +    +P SPP    +S
Sbjct: 438 APFSPPPSPPVQAPFSPPASPPVSPSA-TPPSQAPPSLAAPPLQVPPSPPASPPMS 492



 Score = 41.6 bits (96), Expect = 0.011
 Identities = 79/312 (25%), Positives = 103/312 (33%), Gaps = 64/312 (20%)

Query: 1862 PAGPEGPLPE------PPDGEELSQAEATKAGGKEPEEKATPSPSPAHTCDQC----AIS 1911
            PA P  P P+      PP      +  A   G       ATPSPS A          A  
Sbjct: 266  PAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATP 325

Query: 1912 FSSQDLLTSHRRLHFLPSLQPSAPPQLLDLPLLVFGERNPLVAATSPMPGPPLKRKHE-- 1969
             SS         L   P   PSAPP L  LP        P   AT+ +  P L+  H   
Sbjct: 326  HSSSLTCQLATPLPLAPP-SPSAPPSLQTLPS---PPATPPSQATTSLGSPTLQATHSFL 381

Query: 1970 -DGSLSPTGSEAGGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEV 2028
                LSP  +         PP        + P Q           ++P    L   S + 
Sbjct: 382  PSPPLSPLAT---------PPPQAPPALALPPLQAPP-----SPPASPPLSPLATPSPQA 427

Query: 2029 --GLKKRVVQVWFQNTRARERKGQFRSTPGGVP-SPAVKPPATATPASLPKFNLLLGKVD 2085
               L   ++Q  F    +   +  F S P   P SP+  PP+ A P+             
Sbjct: 428  PNALAVHLLQAPFSPPPSPPVQAPF-SPPASPPVSPSATPPSQAPPSLA----------- 475

Query: 2086 DGTGREAPKREAPAFPYPTATLASGPQPFLPPGKEATTPTPEPPLPLLPPPPPSEEEGPE 2145
                  AP  + P  P           P  PP   + TP P+ P PL  PP    +  P+
Sbjct: 476  ------APPLQVPPSP-----------PASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQ 518

Query: 2146 EPPK-ASPESEA 2156
             PP  A+P  +A
Sbjct: 519  APPALATPPLQA 530



 Score = 41.6 bits (96), Expect = 0.011
 Identities = 36/135 (26%), Positives = 50/135 (37%), Gaps = 13/135 (9%)

Query: 2058 VPSPAVKPPATATPA----SLPKFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQP 2113
            +PSP   PP+ AT +    +L   +  L           P +  PA   P       P P
Sbjct: 354  LPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-P 412

Query: 2114 FLPPGKEATTPTPEPPLPL--------LPPPPPSEEEGPEEPPKASPESEACSLSAGDLS 2165
              PP     TP+P+ P  L          PPP    + P  PP + P S + +  +    
Sbjct: 413  ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 472

Query: 2166 DSSASSLAEPESPGA 2180
              +A  L  P SP A
Sbjct: 473  SLAAPPLQVPPSPPA 487



 Score = 40.4 bits (93), Expect = 0.024
 Identities = 39/123 (31%), Positives = 45/123 (36%), Gaps = 19/123 (15%)

Query: 605 PLGLPPGLMGPG---PPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRPDKPLEAQ 661
           P   PP L  P    PP PP + P SP        P  L  P   LA P   P  P    
Sbjct: 467 PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKP--PPQAP--PA 522

Query: 662 LLLNGFHHVGAPARKFPTSAPGSLSPDAHLPPSQL----------LGSSSDSLPTSPPPD 711
           L       + +P   FP  AP   SP A LP S L          L +    +P SPP  
Sbjct: 523 LATPPLQALPSPPASFPGQAP--FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPAS 580

Query: 712 DSL 714
            +L
Sbjct: 581 PTL 583



 Score = 40.0 bits (92), Expect = 0.031
 Identities = 71/288 (24%), Positives = 91/288 (31%), Gaps = 34/288 (11%)

Query: 1453 GLPFLSPP---PPPLDLHRFPAPLFTPPVLPPFPLVPESLLKLQQQQLLLPFYLHD---- 1505
            GL  L PP   PP  D      PL + P+  P P    S     Q    LP   H     
Sbjct: 276  GLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP----SAALQSQAPPTLPATPHSSSLT 331

Query: 1506 LKVGPKLTLAGPAPVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPSSPPDPL 1565
             ++   L LA P+P       T P PP  P ++         P  +  +   PS P  PL
Sbjct: 332  CQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGS--PTLQATHSFLPSPPLSPL 389

Query: 1566 PNEAARTAAKALLENFGFELVIQYNEGKQAVPPPPTPPPPEALGGGDKLACGACGKLFSN 1625
                 +      L               QA P PP  PP   L      A  A       
Sbjct: 390  ATPPPQAPPALALPPL------------QAPPSPPASPPLSPLATPSPQAPNALAVHLLQ 437

Query: 1626 MLILKTHEEHVHRRFLPFEA--LSRYAAQFRKSYDSLY-PPLAEPPKPPDGSLDSPV--- 1679
                      V   F P  +  +S  A    ++  SL  PPL  PP PP     SP    
Sbjct: 438  APFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP 497

Query: 1680 -PHLGPPFLVPEPEAGGTRAPEERSRAGGHWPIEEEESSRGNLPPLVP 1726
             P   PP   P  +    + P +   A    P++   S   + P   P
Sbjct: 498  PPQAPPPLAAPPLQL--AKPPPQAPPALATPPLQALPSPPASFPGQAP 543



 Score = 40.0 bits (92), Expect = 0.031
 Identities = 42/146 (28%), Positives = 56/146 (38%), Gaps = 26/146 (17%)

Query: 2049 GQFRSTPGGVPSP--AVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAFPYPTAT 2106
            G   S+P   PSP  A++  A  T  + P  + L  ++        P   AP  P    +
Sbjct: 297  GPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQL------ATPLPLAPPSPSAPPS 350

Query: 2107 LASGPQPFLPPGKEATT----PT--------PEPPLPLLPPPPPSEEEGPEEPPKASPES 2154
            L + P P   P  +ATT    PT        P PPL  L  PPP        PP  +P S
Sbjct: 351  LQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPS 410

Query: 2155 EACSLSAGDLSDSSASSLAEPESPGA 2180
               S     L+  S      P++P A
Sbjct: 411  PPASPPLSPLATPS------PQAPNA 430



 Score = 38.9 bits (89), Expect = 0.070
 Identities = 84/322 (26%), Positives = 107/322 (33%), Gaps = 77/322 (23%)

Query: 2328 APEAPPALKA------PPATTPASMPLGAAPTLPRLAPVLLSGPALAQPPLGNLAPFNSG 2381
            AP A P   A      P +  PAS     AP     +P  +S P  A    G   P   G
Sbjct: 74   APRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRAS---GTTRP---G 127

Query: 2382 PAASSGLL---------GLAT-----SVLPTTTVVQTAGP--GRPLPQRPMPDQTNTSTA 2425
            P    GL          G AT     S L       T+GP  G P P      +   +  
Sbjct: 128  PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEV 187

Query: 2426 GTTDPVPG----PPTEPLGDKVSS-------------ERKPVAGPTSSSNDALKNLKALK 2468
            G   P P     PPTE     VSS              R+P AG       A ++L +  
Sbjct: 188  GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGG-GLQRPASRSLSSSA 246

Query: 2469 TTV--PALLGGQFLPFPLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFP-MNPMIPQT 2525
            T +  PA  G      P  PA  + P       LQ     Q+   +K   P + P+    
Sbjct: 247  TPLSSPARSGPSARGTPRAPAHPSQPKP---KGLQALRPPQVTPPRKDAAPALGPLSSSP 303

Query: 2526 LIGLLPNALLQ---PPPQPPEP------------------TATAPPKPPELPAPGEGEAG 2564
            L    P+A LQ   PP  P  P                  + +APP    LP+P      
Sbjct: 304  LATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPS 363

Query: 2565 EVDELLTGSTGISTVDVTHRYL 2586
            +     T S G  T+  TH +L
Sbjct: 364  QA----TTSLGSPTLQATHSFL 381



 Score = 38.9 bits (89), Expect = 0.070
 Identities = 70/284 (24%), Positives = 95/284 (33%), Gaps = 69/284 (24%)

Query: 1420 EGPERSQEEPKEGETEGEVGTEKKGPDTSGFIS--GLPFLSPPPPPLD--LHRFPAPLFT 1475
            EGP +S     E  T       ++ P   G +       LS    PL       P+   T
Sbjct: 203  EGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGT 262

Query: 1476 P--PVLPPFPLVPESLLKLQQQQLLLPFYLHDLKVGPKLT--LAGPAPVLSLPAATPPPP 1531
            P  P  P  P  P+ L  L+  Q+  P       +GP  +  LA P+P  +L +  PP  
Sbjct: 263  PRAPAHPSQPK-PKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTL 321

Query: 1532 PQPPKAELAEREWERP-PMAKEGNEAGPSSPPDPLPNEAARTAAKALLENFGFELVIQYN 1590
            P  P +     +   P P+A       PS+PP                            
Sbjct: 322  PATPHSSSLTCQLATPLPLAPPS----PSAPPS--------------------------- 350

Query: 1591 EGKQAVPPPPTPPPPEALGGGDKLACGACGKLFSNMLILKTHEEHVHRRFLPFEALSRYA 1650
               Q +P PP  PP +A                 +  +  TH       FLP   LS  A
Sbjct: 351  --LQTLPSPPATPPSQATTS------------LGSPTLQATHS------FLPSPPLSPLA 390

Query: 1651 AQFRKSYDSL-YPPLAEPPKPPDGSLDSPVPHLGPPFLVPEPEA 1693
                ++  +L  PPL  PP PP        P L  P   P P+A
Sbjct: 391  TPPPQAPPALALPPLQAPPSPPAS------PPLS-PLATPSPQA 427



 Score = 37.0 bits (84), Expect = 0.26
 Identities = 49/188 (26%), Positives = 67/188 (35%), Gaps = 41/188 (21%)

Query: 1471 APLFTPPVLPPFPLVPESLLKLQQQQLLLPFYLHDLKV---GPKLTLAGPAPVLSLPAAT 1527
            +PL TPP   P P++   LL++       P      +    GP  +++GP   L+L    
Sbjct: 553  SPLATPPPQAP-PVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP 611

Query: 1528 PPPPPQPPKAELA-------EREWERPPMAKEGNEAGP------SSPPD----------- 1563
            PPPP + P + L+              P    G ++GP      S PPD           
Sbjct: 612  PPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAW 671

Query: 1564 ---PLPNEAARTAAKALLE--------NFGFELVIQYNEGKQAVPPPP--TPPPPEALGG 1610
               P P  A R A  A L         +      I   EG ++  P P    P P     
Sbjct: 672  SRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTS 731

Query: 1611 GDKLACGA 1618
            G K A GA
Sbjct: 732  GGKAAAGA 739



 Score = 36.2 bits (82), Expect = 0.45
 Identities = 29/95 (30%), Positives = 39/95 (41%), Gaps = 18/95 (18%)

Query: 1213 SLYFLLSPLEGPNLTPEASP-DPLPEPPLASVEVPDKPSGSPGQ--------PPSPAPSP 1263
            +++ L +P   P   P  +P  P   PP++    P  PS +P          PPSP  SP
Sbjct: 432  AVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATP--PSQAPPSLAAPPLQVPPSPPASP 489

Query: 1264 VPEPDAQAEDVAPPPTMAEEEEGTTGELRSAEPAP 1298
               P A     APPP  A         L+ A+P P
Sbjct: 490  PMSPSATPPPQAPPPLAAP-------PLQLAKPPP 517



 Score = 35.8 bits (81), Expect = 0.59
 Identities = 81/370 (21%), Positives = 117/370 (31%), Gaps = 43/370 (11%)

Query: 72  EIGEPQEGPDCGHFPPNDPGVEKDKEQEEEEEGLPPMDLSNHLFFTAGGEAYLVAKLSLP 131
           E+G P+  P     PP + G  K      E     P   +       GG     ++    
Sbjct: 186 EVGLPRPAPSARPRPPTE-GPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS 244

Query: 132 GGSELLLPKGFPWGEAGIKEEPSLPFLAYPPPSHLTALHIQHGFDPIQGFSSS-DQILSH 190
             + L  P        G    P+ P  + P P  L AL       P +  + +   + S 
Sbjct: 245 SATPLSSPARSGPSARGTPRAPAHP--SQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS 302

Query: 191 DTSAPSPAACEERHGAFWSYQLAPNPPGDPKDGPMGNSGGNHVAVFWLCLLCRLGFSKPQ 250
             + PSP+A  +        Q  P  P  P                   L C+L    P 
Sbjct: 303 PLATPSPSAALQS-------QAPPTLPATPHSSS---------------LTCQLATPLPL 340

Query: 251 AFMDHTQSHGVKLTPAQYQGLSGSPAVLQEGDEGCKALISFLEPKLPARPSSDIPLDNSS 310
           A    +    ++  P+       S A    G    +A  SFL P  P  P +  P     
Sbjct: 341 APPSPSAPPSLQTLPSP-PATPPSQATTSLGSPTLQATHSFL-PSPPLSPLATPPPQAPP 398

Query: 311 TVNMEANVAQTED--GPPEAEVQALILLDEEVMAL----SPPSPPTATWDPSPTQAKESP 364
            + +    A       PP + +          +A+    +P SPP +     P QA  SP
Sbjct: 399 ALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP----PVQAPFSP 454

Query: 365 VAAGEAGPDWFPEGQEEDGGLCPPLNQSSPTSKEGGTLPAPVGSPEDPSDPP---QPYRL 421
            A+    P   P  Q       PPL    P S       +P  +P   + PP    P +L
Sbjct: 455 PASPPVSPSATPPSQAPPSLAAPPL--QVPPSPPASPPMSPSATPPPQAPPPLAAPPLQL 512

Query: 422 ADDYTPAPAA 431
           A     AP A
Sbjct: 513 AKPPPQAPPA 522



 Score = 35.0 bits (79), Expect = 1.0
 Identities = 24/66 (36%), Positives = 32/66 (48%), Gaps = 8/66 (12%)

Query: 1221 LEGPNLTPEASPDPLPEPPLA--SVEVPDKPSGSPGQPPSPAPSPVPEPDAQAEDV---- 1274
            L  P L+P A+P P   P LA   ++ P  P  SP   P   PSP   P+A A  +    
Sbjct: 381  LPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSP-QAPNALAVHLLQAP 439

Query: 1275 -APPPT 1279
             +PPP+
Sbjct: 440  FSPPPS 445



 Score = 35.0 bits (79), Expect = 1.0
 Identities = 24/68 (35%), Positives = 28/68 (41%), Gaps = 6/68 (8%)

Query: 1219 SPLEGPNLTPEASPDPLPEPPLASVEVPDKPSGSPGQPP-----SPAPSPVPEPDAQAED 1273
            SP   P L+P A+P P   P   +V +   P   P  PP     SP  SP   P A    
Sbjct: 410  SPPASPPLSPLATPSP-QAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS 468

Query: 1274 VAPPPTMA 1281
             APP   A
Sbjct: 469  QAPPSLAA 476



 Score = 34.7 bits (78), Expect = 1.3
 Identities = 29/105 (27%), Positives = 39/105 (37%), Gaps = 25/105 (23%)

Query: 1219 SPLEGPNLTPEASPDPLPEPPLAS--VEVPDKPSGSPG-----QPPSP------------ 1259
            SP     ++P A+P P   P LA+  ++VP  P  SP      +PP+P            
Sbjct: 545  SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLT 604

Query: 1260 ---APSPVPEPDAQAEDVAPPPTMAEEEEGTTG---ELRSAEPAP 1298
               AP P P P          P +A      T    ELR  +  P
Sbjct: 605  LALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGP 649



 Score = 33.9 bits (76), Expect = 2.2
 Identities = 25/81 (30%), Positives = 32/81 (39%), Gaps = 22/81 (27%)

Query: 1219 SPLEGPNLTPEASPDPLPEPPLASVEV---------------------PDKPSGSPGQPP 1257
            SP   P ++P A+P P   PPLA+  +                     P  P+  PGQ P
Sbjct: 484  SPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAP 543

Query: 1258 -SPAPSPVPEPDAQAEDVAPP 1277
             SP+ S    P A     APP
Sbjct: 544  FSPSASLPMSPLATPPPQAPP 564



 Score = 33.5 bits (75), Expect = 2.9
 Identities = 24/75 (32%), Positives = 30/75 (40%), Gaps = 15/75 (20%)

Query: 1219 SPLEGPNLTPEASPD----------PLPEPPLASVEVPDKPSGSPGQPPSPAPSPVPEPD 1268
            SP   P ++P A+P           PL  PP      P  PS +   PP  AP P+  P 
Sbjct: 453  SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSAT---PPPQAPPPLAAPP 509

Query: 1269 AQAEDVAP--PPTMA 1281
             Q     P  PP +A
Sbjct: 510  LQLAKPPPQAPPALA 524



 Score = 32.7 bits (73), Expect = 5.0
 Identities = 48/183 (26%), Positives = 57/183 (31%), Gaps = 42/183 (22%)

Query: 548 SPPEASLPPSAGDKEPKTKSSWQCKVCSYETNISRNLRIHMTSEKHMQNVLMLHQ-GLPL 606
           +PP  +LPP      P                 S  L    T      N L +H    P 
Sbjct: 396 APPALALPPLQAPPSPPA---------------SPPLSPLATPSPQAPNALAVHLLQAPF 440

Query: 607 GLPPGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQ-----TPLAGPGLRPD------ 655
             PP      P  PP + P SP        P +L  P      +P A P + P       
Sbjct: 441 SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 500

Query: 656 --KPLEAQLLLNGFHHVGAPARKFPTSAPGSLSPDAHLPPSQLLGSSSDSLPTSPPPDDS 713
              PL A  L            K P  AP +L+     PP Q L S   S P   P   S
Sbjct: 501 APPPLAAPPL---------QLAKPPPQAPPALA----TPPLQALPSPPASFPGQAPFSPS 547

Query: 714 LSL 716
            SL
Sbjct: 548 ASL 550



 Score = 32.7 bits (73), Expect = 5.0
 Identities = 51/195 (26%), Positives = 65/195 (33%), Gaps = 61/195 (31%)

Query: 2060 SPAVKPPATATPASLPKFNLLLGKVDDGTGR--------EAPKREAPAFPYPTATLAS-- 2109
            +P   PP + +P+S      L G     T            P+  A A P P A LA+  
Sbjct: 608  APGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACH 667

Query: 2110 ------GPQPFLPPGKEATTPTPEPPLPLLPPPPPS---------EEEGPEEP------- 2147
                  GP P L     A    P  PLP  P   P          E EGPE         
Sbjct: 668  PAAWSRGPAPPL-----AFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGAL 722

Query: 2148 -PKASPESEACSLSAGDLSDSSASSLAEP---ESP--------------------GAGGT 2183
             P  SP +     +AG  + +S+ S  +    E P                     A G 
Sbjct: 723  DPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGA 782

Query: 2184 SGGPGGGTGVPDGMG 2198
            +GG GGG G  +G G
Sbjct: 783  AGGSGGGPGGAEGGG 797



 Score = 32.0 bits (71), Expect = 8.5
 Identities = 63/257 (24%), Positives = 87/257 (33%), Gaps = 56/257 (21%)

Query: 2326 APAPEAPPALKAPPATTPA--SMPLGAAPTLPRLAPVLLSGPALAQPPLGNLAPFNSGPA 2383
            A A    PA +AP   TP     P    P  P    VL +  A+ + PL   A       
Sbjct: 10   AGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAG------ 63

Query: 2384 ASSGLLGLATSVLPTTTVVQTAGPGRPLPQRPMPDQTNTSTAGTT--DPVPGPPTEPLGD 2441
                  G+  + +P +     AGP              T +AGT+  +P   PP    G+
Sbjct: 64   ------GIGGATIPESA--PRAGP--------------TRSAGTSSRNPASRPPASGRGE 101

Query: 2442 KVSSERKPVAGPTSSSNDALKNLKALKTTVPALLGGQFLPFPLPP--AGGTAPPAVFGPQ 2499
            +    +    GP SS        +A  TT P  LG + L        A G A  A     
Sbjct: 102  RAPPAKNTSPGPVSSPG------RASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSA 155

Query: 2500 LQGAYFQQLYGMKKGLFPMNPMIPQ-----TLIGL---LPNALLQPPPQPPEPT------ 2545
            L     +   G   G  P   M  +     T +GL    P+A  +PP + P  +      
Sbjct: 156  LSAGARRDTSGPTPGT-PSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 214

Query: 2546 -ATAPPKPPELPAPGEG 2561
             +T  P P     P  G
Sbjct: 215  HSTTEPSPAARRRPSAG 231


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 62.8 bits (151), Expect = 4e-09
 Identities = 74/252 (29%), Positives = 86/252 (34%), Gaps = 42/252 (16%)

Query: 2328 APEAPPALKAPPATTPASMPLGAAPTLPRLAPVLLSGPALAQPPLGNLAPFNSGPAASSG 2387
            APE PPA +A P       P    P  PR  P++ +GPA   PP   L P   G A S  
Sbjct: 86   APEPPPAGRARPGGGGPQRP---GPPSPR-RPLVPAGPA---PPAAKLRPPPEGSAGSCA 138

Query: 2388 LLGLATSVLPTTTVVQTAGPGRPLPQRPMPDQTNTSTAGTTDPVPGP-PTEPLGDKVSSE 2446
             +  A +V         AGP  P P  P       + A    P PGP P    G      
Sbjct: 139  PVPAAAAV--------AAGP-EPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKP 189

Query: 2447 RKPVAGPTSSSNDALKNLKALKTTVPALLG---GQFLPFPLPPAGGT-----------AP 2492
              P A  T + + AL N         +L+       LP P P A GT           AP
Sbjct: 190  AGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAP 249

Query: 2493 PAVFGPQLQGAYFQQLYGMKKGLFPMNPMIPQTLIGLLPNALLQPPPQPPEPTATAPPKP 2552
            PA   P    A             P  P          P  L +PP  P  P   AP  P
Sbjct: 250  PAPAAPSPPAA-----------PAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVP 298

Query: 2553 PELPAPGEGEAG 2564
            P   A   G AG
Sbjct: 299  PPAAAQNGGSAG 310



 Score = 53.9 bits (128), Expect = 2e-06
 Identities = 95/407 (23%), Positives = 133/407 (32%), Gaps = 86/407 (21%)

Query: 2061 PAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQPFLPPGKE 2120
            P  KP A  T    P F           G  AP   APA P P A  A        P   
Sbjct: 227  PLPKPAAPGTVIQTPPF----------VGAAAPP--APAAPSPPAAPA--------PAAP 266

Query: 2121 ATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESEACSLSAGDLSDSSASSLAEPESPGA 2180
            A  P P PP P     PP    GP     A P   A         +  ++  A   +P A
Sbjct: 267  AAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQ-------NGGSAGAAPAPAPAA 319

Query: 2181 GGTSG-----GPGGGTGVPDGMGQRRYRTQMSSLQLKIMKACYEAYRT------------ 2223
            GG +G     GPG     P   G +      +    ++++A   A +T            
Sbjct: 320  GGPAGVSGQPGPGAAAAAP-APGVK------AESPKRVVQAAPPAAQTLAASGPASTAAS 372

Query: 2224 ----PTMQEC---------EVLGEEIGLPKRVIQVWFQNARAKEKKAKLQGTAAGSTGGS 2270
                PTMQ              G   GLPK         A  +        T +G     
Sbjct: 373  MVIGPTMQGALPSPAAVPPPAPGTPTGLPKGA-----AGAVTQSLSRTPTATTSGIRATL 427

Query: 2271 SEGLLAAQRTDCPYCDVKYDFYVSCRGHLFSRQ---HLAKLKEAVRAQLKSESKCY---D 2324
            +  +LA +    P        +    G +  R     L  + +   AQ+++++       
Sbjct: 428  TPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTT 487

Query: 2325 LAPAPEAPPALKAPPATTPASMPLGAAPTLPRLAP-VLLSGPALAQPPLGNLAPFNSGPA 2383
            +AP P  P +  APP         G      ++ P  ++   + AQ  +   A     P 
Sbjct: 488  MAPRPATPTS--APPVQISTVQAPGTPIIARQVTPTTIIKQVSQAQTTVQPSATLQRSPG 545

Query: 2384 ASSGLL---GLATSVLPTTTVVQTAGPGRPLPQRPMPDQTNTSTAGT 2427
                L+      T+ L T T VQT       PQR +P  T TS+A T
Sbjct: 546  VQPQLVLGGAAQTASLGTATAVQTG-----TPQRTVPGATTTSSAAT 587



 Score = 45.4 bits (106), Expect = 7e-04
 Identities = 80/283 (28%), Positives = 100/283 (35%), Gaps = 45/283 (15%)

Query: 2326 APAPEAPPALKAPPATTPASMPLGAAPTLPRLAPVLLSGPALAQPPLGNLAPFNSGPAAS 2385
            APA  A PA  A  A      P       P   P   +GP  AQ   G+ A  NS  AA+
Sbjct: 153  APAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAA 212

Query: 2386 ----------SGLLGLATSVLPTTTVVQT----AGPGRPLPQRPMPDQTNTSTAGTTDPV 2431
                      + LL L     P  TV+QT         P P  P P       A    P 
Sbjct: 213  PAVSLVNNGPAALLPLPKPAAP-GTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPP 271

Query: 2432 PGPPTEPLGDKVSSERKP--VAGPTSSSNDALKNLKALKTTVPALLGGQ--FLPFPLPPA 2487
            P PP        +  R P   AGP +++        A+     A  GG     P P P A
Sbjct: 272  PPPPA-----PATLARPPGHPAGPPTAA-------PAVPPPAAAQNGGSAGAAPAPAPAA 319

Query: 2488 GGTAPPAVFG-PQLQGAYFQQLYGMK----KGLFPMNPMIPQTLIGLLP-----NALLQP 2537
            GG  P  V G P    A      G+K    K +    P   QTL    P     + ++ P
Sbjct: 320  GG--PAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGP 377

Query: 2538 PPQP--PEPTATAPPKPPELPAPGEGEAGEVDELLTGSTGIST 2578
              Q   P P A  PP P       +G AG V + L+ +   +T
Sbjct: 378  TMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATT 420



 Score = 44.7 bits (104), Expect = 0.001
 Identities = 42/146 (28%), Positives = 52/146 (35%), Gaps = 19/146 (13%)

Query: 2054 TPGGVPSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQP 2113
            +P G        PA   P + P+            GR  P    P  P P     S  +P
Sbjct: 66   SPAGAAGAGPAAPAEGAPGAAPE--------PPPAGRARPGGGGPQRPGPP----SPRRP 113

Query: 2114 FLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESEACSLSAGDLSDSSASSLA 2173
             +P G     P P P   L PPP  S       P  A+  +      AG    +  ++LA
Sbjct: 114  LVPAG-----PAP-PAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALA 167

Query: 2174 EPESPGAG-GTSGGPGGGTGVPDGMG 2198
                PG G G   GPG G G P G G
Sbjct: 168  ARAGPGPGPGPGPGPGPGPGKPAGPG 193



 Score = 43.1 bits (100), Expect = 0.004
 Identities = 81/323 (25%), Positives = 108/323 (33%), Gaps = 72/323 (22%)

Query: 2326 APAPEAPPALKAPPATTPASMPLGAAPTLPRLAPVLLSGPALAQPPL---------GNL- 2375
            APA  +PPA  AP A   A  P   AP      P   +GP  A P +         G+  
Sbjct: 251  APAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAG 310

Query: 2376 -----APFNSGPAASSGLLGLATSVLPTTTVVQTAGPGRPLPQRPMPDQTNT-------- 2422
                 AP   GPA  SG  G   +       V+   P R +   P   QT          
Sbjct: 311  AAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTA 370

Query: 2423 --------------STAGTTDPVPGPPTE-PLGDKVSSERKPVAGPTSSSNDALKNLKAL 2467
                          S A    P PG PT  P G   +  +     PT++++     ++A 
Sbjct: 371  ASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTS----GIRA- 425

Query: 2468 KTTVPALLGGQFLPFPLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNPMIPQTLI 2527
             T  P +L  +    P PP     P  +   QL       L   + G   M P   Q L 
Sbjct: 426  -TLTPTVLAPR---LPQPPQN---PTNIQNFQLPPG--MVLVRSENGQLLMIPQ--QALA 474

Query: 2528 GLLPNALLQP----PPQPPEPTATAPPKPPELPAPGEGEAGEVDELLTGSTGISTVDVTH 2583
             +   A  QP     P+P  PT+  P +   + APG              T I    VT 
Sbjct: 475  QMQAQAHAQPQTTMAPRPATPTSAPPVQISTVQAPG--------------TPIIARQVTP 520

Query: 2584 RYLCRQCKMAFDGEAPATAHQRS 2606
              + +Q   A     P+   QRS
Sbjct: 521  TTIIKQVSQAQTTVQPSATLQRS 543



 Score = 42.0 bits (97), Expect = 0.008
 Identities = 32/112 (28%), Positives = 41/112 (36%), Gaps = 18/112 (16%)

Query: 614 GPGPPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRPDKP--------LEAQLLLN 665
           GP P P   A P  P  L    GP   G    P  GPG  P KP        L     L 
Sbjct: 149 GPEPAPAGPAKPAGPAALAARAGP---GPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALL 205

Query: 666 GFHHVGAPARKFPTSAPGSL-------SPDAHLPPSQLLGSSSDSLPTSPPP 710
             HH  APA     + P +L       +P   +     +G+++   P +P P
Sbjct: 206 NSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSP 257



 Score = 37.4 bits (85), Expect = 0.20
 Identities = 34/94 (36%), Positives = 39/94 (41%), Gaps = 18/94 (19%)

Query: 1515 AGPAPVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPSS------PPDPLPNE 1568
            A PAP  + PAA PPPPP P  A LA     RPP    G+ AGP +      PP    N 
Sbjct: 259  AAPAP--AAPAAAPPPPP-PAPATLA-----RPP----GHPAGPPTAAPAVPPPAAAQNG 306

Query: 1569 AARTAAKALLENFGFELVIQYNEGKQAVPPPPTP 1602
             +  AA A     G    +    G  A    P P
Sbjct: 307  GSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAP 340



 Score = 36.6 bits (83), Expect = 0.35
 Identities = 30/94 (31%), Positives = 33/94 (35%), Gaps = 19/94 (20%)

Query: 1223 GPNLTPEASPDPLPEPPLASVEVPDKPSGSPGQPPSP-------APSPV-----PEPDAQ 1270
            GP    E +P   PEPP A    P         PPSP        P+P      P P+  
Sbjct: 74   GPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGS 133

Query: 1271 AEDVAPPPTMAEEEEGTTGELRSAEPAPADSRHP 1304
            A   AP P  A    G        EPAPA    P
Sbjct: 134  AGSCAPVPAAAAVAAG-------PEPAPAGPAKP 160



 Score = 35.8 bits (81), Expect = 0.59
 Identities = 71/288 (24%), Positives = 81/288 (28%), Gaps = 76/288 (26%)

Query: 1432 GETEGEVGTEKKGPDTSGFISGLPFLSPPPPPLDLHR--FPAPLFTPPVLPPFPLVPESL 1489
            G   G  G     P       G P  +P PPP    R     P    P  P  PLVP   
Sbjct: 65   GSPAGAAGAGPAAP-----AEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVP--- 116

Query: 1490 LKLQQQQLLLPFYLHDLKVGPKLTLAGPAPVLSLPAATPPPPPQPPKAELAEREWERPPM 1549
                                     AGPAP    PAA   PPP+      A      P  
Sbjct: 117  -------------------------AGPAP----PAAKLRPPPEGSAGSCA------PVP 141

Query: 1550 AKEGNEAGPSSPPDPLPNEAARTAAKALLENFGFELVIQYNEGKQAVPPPPTPPPPEALG 1609
            A     AGP    +P P   A+ A  A L              +    P P P P    G
Sbjct: 142  AAAAVAAGP----EPAPAGPAKPAGPAALA------------ARAGPGPGPGPGPGPGPG 185

Query: 1610 GGDKLACGACGKLFSNMLILKTHEEHVHRRF-----------LPFEALSRYAAQFRKSYD 1658
             G     GA   L  +  +L +H                   LP  A      Q      
Sbjct: 186  PGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVG 245

Query: 1659 SLYPPLAEPPKPPDGSLDSPVPHLGPPFLVPEPEAGGTRAPEERSRAG 1706
            +  PP    P PP     +  P   PP   P P A  T A      AG
Sbjct: 246  AAAPPAPAAPSPPAAPAPA-APAAAPP---PPPPAPATLARPPGHPAG 289



 Score = 35.0 bits (79), Expect = 1.0
 Identities = 29/105 (27%), Positives = 41/105 (39%), Gaps = 18/105 (17%)

Query: 1207 LNEVPSSLYFLLSP------LEGPNLTPEASPDPLPEPPLASVEVPDKPSGSPGQPPSPA 1260
            +N  P++L  L  P      ++ P     A+P     P   +   P  P+ +P  PP PA
Sbjct: 218  VNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAP-PPPPPA 276

Query: 1261 PSPVPEPDAQ------AEDVAPPPTMAEEEEGTTGELRSAEPAPA 1299
            P+ +  P         A    PPP  A+      G    A PAPA
Sbjct: 277  PATLARPPGHPAGPPTAAPAVPPPAAAQN-----GGSAGAAPAPA 316



 Score = 34.3 bits (77), Expect = 1.7
 Identities = 21/75 (28%), Positives = 28/75 (37%), Gaps = 4/75 (5%)

Query: 1228 PEASPDPLPEPPLASVEVPDKPSGSPGQPPSPAPSPVPEPDAQAEDVAPPPTMAEEEEGT 1287
            P A+P P P  P      P  P+G P   P+  P    +    A     P   A    G 
Sbjct: 266  PAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGV 325

Query: 1288 TGE----LRSAEPAP 1298
            +G+      +A PAP
Sbjct: 326  SGQPGPGAAAAAPAP 340


>gi|24497589 aristaless related homeobox [Homo sapiens]
          Length = 562

 Score = 62.8 bits (151), Expect = 4e-09
 Identities = 67/247 (27%), Positives = 98/247 (39%), Gaps = 32/247 (12%)

Query: 2150 ASPESEACSLSAGDLSDSSASSLAEPESPGAGGT-SGGPGGGTGVPDGM---GQRRYRTQ 2205
            A+  + A +   G+LS      L   ++ G  G  S     G+   +G+    QRRYRT 
Sbjct: 275  AAAAAAAVATEGGELSPKEELLLHPEDAEGKDGEDSVCLSAGSDSEEGLLKRKQRRYRTT 334

Query: 2206 MSSLQLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAKLQGTAAG 2265
             +S QL+ ++  ++    P +   E L   + L +  +QVWFQN RAK +K +  G    
Sbjct: 335  FTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKREKAGAQTH 394

Query: 2266 STGGSSEGLLAAQRTDCPYCDVKYDFYVSCRGHLFSRQHLAKLKEAVRAQLKSESKCYDL 2325
              G    G L+A     PY D             F   H A L  A  A   + +  +  
Sbjct: 395  PPGLPFPGPLSATHPLSPYLDAS----------PFPPHHPA-LDSAWTAAAAAAAAAFPS 443

Query: 2326 APAPEAPPALKAPPATTPASMP--LGAAPTLPRLAPVLLSGPALAQPPLGNL----APFN 2379
             P P  P +   PP+  P  +   LGAA         +   PA   P  G L    AP  
Sbjct: 444  LPPP--PGSASLPPSGAPLGLSTFLGAA---------VFRHPAFISPAFGRLFSTMAPLT 492

Query: 2380 SGPAASS 2386
            S   A++
Sbjct: 493  SASTAAA 499



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 75/319 (23%), Positives = 109/319 (34%), Gaps = 86/319 (26%)

Query: 1833 EEEEEEAERGEEEEEVEEEEVEEEQGLEPPAGPEGPLPEPPDGEELSQAEATKAGGKEPE 1892
            E++EEE    EE+E+ EEE +E+++                  EEL + +A +A  KEP 
Sbjct: 224  EDDEEELLEDEEDEDEEEELLEDDE------------------EELLEDDA-RALLKEPR 264

Query: 1893 EKATPSPSPAHTCDQCAISFSSQDLLTSHRRLHFLPSLQPSAPPQLLDLPLLVFGERNPL 1952
                 +          A++    +L      L      +               GE +  
Sbjct: 265  RCPVAATGAVAAAAAAAVATEGGELSPKEELLLHPEDAEGKD------------GEDSVC 312

Query: 1953 VAATSPMPGPPLKRKHEDGSLSPTGSEAGGGGEGEPPRDKRLRTTILPEQLEILYRWYMQ 2012
            ++A S      LKRK                        +R RTT    QLE L R + +
Sbjct: 313  LSAGSDSEEGLLKRKQ-----------------------RRYRTTFTSYQLEELERAFQK 349

Query: 2013 DSNPTRKMLDCISEEVGLKKRVVQVWFQNTRARERKGQ---FRSTPGGVPSPAVKPPATA 2069
               P     + ++  + L +  VQVWFQN RA+ RK +    ++ P G+P P    P +A
Sbjct: 350  THYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKREKAGAQTHPPGLPFPG---PLSA 406

Query: 2070 TPASLPKFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQPFLPPGKEATTPTPEPP 2129
            T                           P  PY  A+      P L     A        
Sbjct: 407  T--------------------------HPLSPYLDASPFPPHHPALDSAWTAAAAAAAAA 440

Query: 2130 LPLLPPPPPSEEEGPEEPP 2148
             P LPPPP S    P   P
Sbjct: 441  FPSLPPPPGSASLPPSGAP 459



 Score = 45.1 bits (105), Expect = 0.001
 Identities = 27/68 (39%), Positives = 34/68 (50%)

Query: 1724 LVPAGRRFSRTKFTEFQTQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQK 1783
            L+   +R  RT FT +Q + L+  F+ + YP     E LA  L L    V VWFQN R K
Sbjct: 323  LLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAK 382

Query: 1784 ARKNACEG 1791
             RK    G
Sbjct: 383  WRKREKAG 390


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.133    0.409 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 151,903,721
Number of Sequences: 37866
Number of extensions: 10384909
Number of successful extensions: 176510
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1147
Number of HSP's successfully gapped in prelim test: 2293
Number of HSP's that attempted gapping in prelim test: 60053
Number of HSP's gapped (non-prelim): 87769
length of query: 2706
length of database: 18,247,518
effective HSP length: 120
effective length of query: 2586
effective length of database: 13,703,598
effective search space: 35437504428
effective search space used: 35437504428
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 71 (32.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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