BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|169207592 PREDICTED: zinc finger homeobox 2 [Homo sapiens] (2706 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|169207592 PREDICTED: zinc finger homeobox 2 [Homo sapiens] 5604 0.0 gi|169207014 PREDICTED: zinc finger homeobox 2 [Homo sapiens] 5604 0.0 gi|169207217 PREDICTED: zinc finger homeobox 2 [Homo sapiens] 5598 0.0 gi|118498345 AT-binding transcription factor 1 [Homo sapiens] 531 e-150 gi|126090663 zinc finger homeodomain 4 [Homo sapiens] 500 e-141 gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens] 78 1e-13 gi|153792074 proline rich 12 [Homo sapiens] 75 7e-13 gi|50083287 LIM homeobox 8 [Homo sapiens] 73 3e-12 gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Ho... 73 4e-12 gi|152963644 paired-like homeodomain transcription factor 1 [Hom... 70 3e-11 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 69 5e-11 gi|134284361 LIM homeobox protein 6 isoform 2 [Homo sapiens] 69 6e-11 gi|134284359 LIM homeobox protein 6 isoform 1 [Homo sapiens] 69 6e-11 gi|4505007 LIM homeobox transcription factor 1, beta [Homo sapiens] 68 1e-10 gi|122937321 UNC homeobox [Homo sapiens] 68 1e-10 gi|33569216 LIM homeobox 9 isoform 1 [Homo sapiens] 68 1e-10 gi|62241033 LIM homeobox 9 isoform 2 [Homo sapiens] 68 1e-10 gi|47132519 Ras association and pleckstrin homology domains 1 is... 67 2e-10 gi|12707580 paired-like homeobox 2b [Homo sapiens] 66 4e-10 gi|169881277 PROP paired-like homeobox 1 [Homo sapiens] 66 5e-10 gi|156416026 zinc finger protein 219 [Homo sapiens] 65 7e-10 gi|156415998 zinc finger protein 219 [Homo sapiens] 65 7e-10 gi|156415996 zinc finger protein 219 [Homo sapiens] 65 7e-10 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 65 1e-09 gi|148277064 cut-like homeobox 1 isoform a [Homo sapiens] 64 2e-09 gi|30023847 LIM homeobox protein 3 isoform a [Homo sapiens] 64 2e-09 gi|7657303 LIM homeobox protein 3 isoform b [Homo sapiens] 64 2e-09 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 63 3e-09 gi|110832843 TBP-associated factor 4 [Homo sapiens] 63 4e-09 gi|24497589 aristaless related homeobox [Homo sapiens] 63 4e-09 >gi|169207592 PREDICTED: zinc finger homeobox 2 [Homo sapiens] Length = 2706 Score = 5604 bits (14538), Expect = 0.0 Identities = 2706/2706 (100%), Positives = 2706/2706 (100%) Query: 1 MATLNSASTTGTTPSPGHNAPSLPSDTFSSSTPSDPVTKDPPAASSTSENMRSSEPGGQL 60 MATLNSASTTGTTPSPGHNAPSLPSDTFSSSTPSDPVTKDPPAASSTSENMRSSEPGGQL Sbjct: 1 MATLNSASTTGTTPSPGHNAPSLPSDTFSSSTPSDPVTKDPPAASSTSENMRSSEPGGQL 60 Query: 61 LESGCGLVPPKEIGEPQEGPDCGHFPPNDPGVEKDKEQEEEEEGLPPMDLSNHLFFTAGG 120 LESGCGLVPPKEIGEPQEGPDCGHFPPNDPGVEKDKEQEEEEEGLPPMDLSNHLFFTAGG Sbjct: 61 LESGCGLVPPKEIGEPQEGPDCGHFPPNDPGVEKDKEQEEEEEGLPPMDLSNHLFFTAGG 120 Query: 121 EAYLVAKLSLPGGSELLLPKGFPWGEAGIKEEPSLPFLAYPPPSHLTALHIQHGFDPIQG 180 EAYLVAKLSLPGGSELLLPKGFPWGEAGIKEEPSLPFLAYPPPSHLTALHIQHGFDPIQG Sbjct: 121 EAYLVAKLSLPGGSELLLPKGFPWGEAGIKEEPSLPFLAYPPPSHLTALHIQHGFDPIQG 180 Query: 181 FSSSDQILSHDTSAPSPAACEERHGAFWSYQLAPNPPGDPKDGPMGNSGGNHVAVFWLCL 240 FSSSDQILSHDTSAPSPAACEERHGAFWSYQLAPNPPGDPKDGPMGNSGGNHVAVFWLCL Sbjct: 181 FSSSDQILSHDTSAPSPAACEERHGAFWSYQLAPNPPGDPKDGPMGNSGGNHVAVFWLCL 240 Query: 241 LCRLGFSKPQAFMDHTQSHGVKLTPAQYQGLSGSPAVLQEGDEGCKALISFLEPKLPARP 300 LCRLGFSKPQAFMDHTQSHGVKLTPAQYQGLSGSPAVLQEGDEGCKALISFLEPKLPARP Sbjct: 241 LCRLGFSKPQAFMDHTQSHGVKLTPAQYQGLSGSPAVLQEGDEGCKALISFLEPKLPARP 300 Query: 301 SSDIPLDNSSTVNMEANVAQTEDGPPEAEVQALILLDEEVMALSPPSPPTATWDPSPTQA 360 SSDIPLDNSSTVNMEANVAQTEDGPPEAEVQALILLDEEVMALSPPSPPTATWDPSPTQA Sbjct: 301 SSDIPLDNSSTVNMEANVAQTEDGPPEAEVQALILLDEEVMALSPPSPPTATWDPSPTQA 360 Query: 361 KESPVAAGEAGPDWFPEGQEEDGGLCPPLNQSSPTSKEGGTLPAPVGSPEDPSDPPQPYR 420 KESPVAAGEAGPDWFPEGQEEDGGLCPPLNQSSPTSKEGGTLPAPVGSPEDPSDPPQPYR Sbjct: 361 KESPVAAGEAGPDWFPEGQEEDGGLCPPLNQSSPTSKEGGTLPAPVGSPEDPSDPPQPYR 420 Query: 421 LADDYTPAPAAFQGLSLSSHMSLLHSRNSCKTLKCPKCNWHYKYQQTLDVHMREKHPESN 480 LADDYTPAPAAFQGLSLSSHMSLLHSRNSCKTLKCPKCNWHYKYQQTLDVHMREKHPESN Sbjct: 421 LADDYTPAPAAFQGLSLSSHMSLLHSRNSCKTLKCPKCNWHYKYQQTLDVHMREKHPESN 480 Query: 481 SHCSYCSAGGAHPRLARGESYNCGYKPYRCDVCNYSTTTKGNLSIHMQSDKHLANLQGFQ 540 SHCSYCSAGGAHPRLARGESYNCGYKPYRCDVCNYSTTTKGNLSIHMQSDKHLANLQGFQ Sbjct: 481 SHCSYCSAGGAHPRLARGESYNCGYKPYRCDVCNYSTTTKGNLSIHMQSDKHLANLQGFQ 540 Query: 541 AGPGGQGSPPEASLPPSAGDKEPKTKSSWQCKVCSYETNISRNLRIHMTSEKHMQNVLML 600 AGPGGQGSPPEASLPPSAGDKEPKTKSSWQCKVCSYETNISRNLRIHMTSEKHMQNVLML Sbjct: 541 AGPGGQGSPPEASLPPSAGDKEPKTKSSWQCKVCSYETNISRNLRIHMTSEKHMQNVLML 600 Query: 601 HQGLPLGLPPGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRPDKPLEA 660 HQGLPLGLPPGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRPDKPLEA Sbjct: 601 HQGLPLGLPPGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRPDKPLEA 660 Query: 661 QLLLNGFHHVGAPARKFPTSAPGSLSPDAHLPPSQLLGSSSDSLPTSPPPDDSLSLKVFR 720 QLLLNGFHHVGAPARKFPTSAPGSLSPDAHLPPSQLLGSSSDSLPTSPPPDDSLSLKVFR Sbjct: 661 QLLLNGFHHVGAPARKFPTSAPGSLSPDAHLPPSQLLGSSSDSLPTSPPPDDSLSLKVFR 720 Query: 721 CLVCQAFSTDSLELLLYHCSIGRSLPEAEWKEVAGDTHRCKLCCYGTQLKANFQLHLKTD 780 CLVCQAFSTDSLELLLYHCSIGRSLPEAEWKEVAGDTHRCKLCCYGTQLKANFQLHLKTD Sbjct: 721 CLVCQAFSTDSLELLLYHCSIGRSLPEAEWKEVAGDTHRCKLCCYGTQLKANFQLHLKTD 780 Query: 781 KHAQKYQLAAHLREGGGAMGTPSPASLGDGAPYGSVSPLHLRCNICDFESNSKEKMQLHA 840 KHAQKYQLAAHLREGGGAMGTPSPASLGDGAPYGSVSPLHLRCNICDFESNSKEKMQLHA Sbjct: 781 KHAQKYQLAAHLREGGGAMGTPSPASLGDGAPYGSVSPLHLRCNICDFESNSKEKMQLHA 840 Query: 841 RGAAHEENSQIYKVRLGAELGLYHCLLCAWETPSRLAVLQHLRTPAHRDAQAQRRLQLLQ 900 RGAAHEENSQIYKVRLGAELGLYHCLLCAWETPSRLAVLQHLRTPAHRDAQAQRRLQLLQ Sbjct: 841 RGAAHEENSQIYKVRLGAELGLYHCLLCAWETPSRLAVLQHLRTPAHRDAQAQRRLQLLQ 900 Query: 901 NGPTTEEGLAALQSILSFSHGQLRTPAEVVPAEAGNSQPGTIDPEGTGEEPARGCQRLHL 960 NGPTTEEGLAALQSILSFSHGQLRTPAEVVPAEAGNSQPGTIDPEGTGEEPARGCQRLHL Sbjct: 901 NGPTTEEGLAALQSILSFSHGQLRTPAEVVPAEAGNSQPGTIDPEGTGEEPARGCQRLHL 960 Query: 961 KKKKKKKKEWGRASAASKGLCDGGSHPSLTLRPLPICSLQVYCCPYCSFLSPESSQVRAH 1020 KKKKKKKKEWGRASAASKGLCDGGSHPSLTLRPLPICSLQVYCCPYCSFLSPESSQVRAH Sbjct: 961 KKKKKKKKEWGRASAASKGLCDGGSHPSLTLRPLPICSLQVYCCPYCSFLSPESSQVRAH 1020 Query: 1021 TLSQHAVQPKYRCPLCQEQLVGRPALHFHLSHLHNVVPECVEKLLLVVSTGWVRTVQQDL 1080 TLSQHAVQPKYRCPLCQEQLVGRPALHFHLSHLHNVVPECVEKLLLVVSTGWVRTVQQDL Sbjct: 1021 TLSQHAVQPKYRCPLCQEQLVGRPALHFHLSHLHNVVPECVEKLLLVVSTGWVRTVQQDL 1080 Query: 1081 IRAVQEGRKRQGYSGRCMCWGQGAFRQVRVLAGWVRSGIGAVGGGGEATRLFLIAGYNCR 1140 IRAVQEGRKRQGYSGRCMCWGQGAFRQVRVLAGWVRSGIGAVGGGGEATRLFLIAGYNCR Sbjct: 1081 IRAVQEGRKRQGYSGRCMCWGQGAFRQVRVLAGWVRSGIGAVGGGGEATRLFLIAGYNCR 1140 Query: 1141 NDIYNQSAVCTHIKPSGQWPRTPHSWARAYTEQRPGSRKGDSMGQQGLKMTEAKVNCLGI 1200 NDIYNQSAVCTHIKPSGQWPRTPHSWARAYTEQRPGSRKGDSMGQQGLKMTEAKVNCLGI Sbjct: 1141 NDIYNQSAVCTHIKPSGQWPRTPHSWARAYTEQRPGSRKGDSMGQQGLKMTEAKVNCLGI 1200 Query: 1201 EWVGSGLNEVPSSLYFLLSPLEGPNLTPEASPDPLPEPPLASVEVPDKPSGSPGQPPSPA 1260 EWVGSGLNEVPSSLYFLLSPLEGPNLTPEASPDPLPEPPLASVEVPDKPSGSPGQPPSPA Sbjct: 1201 EWVGSGLNEVPSSLYFLLSPLEGPNLTPEASPDPLPEPPLASVEVPDKPSGSPGQPPSPA 1260 Query: 1261 PSPVPEPDAQAEDVAPPPTMAEEEEGTTGELRSAEPAPADSRHPLTYRKTTNFALDKFLD 1320 PSPVPEPDAQAEDVAPPPTMAEEEEGTTGELRSAEPAPADSRHPLTYRKTTNFALDKFLD Sbjct: 1261 PSPVPEPDAQAEDVAPPPTMAEEEEGTTGELRSAEPAPADSRHPLTYRKTTNFALDKFLD 1320 Query: 1321 PARPYKCTVCKESFTQKNILLVHYNSVSHLHKMKKAAIDPSAPARGEAGAPPTTTAATDK 1380 PARPYKCTVCKESFTQKNILLVHYNSVSHLHKMKKAAIDPSAPARGEAGAPPTTTAATDK Sbjct: 1321 PARPYKCTVCKESFTQKNILLVHYNSVSHLHKMKKAAIDPSAPARGEAGAPPTTTAATDK 1380 Query: 1381 PFKCTVCRVSYNQSSTLEIHMRSVLHQTRSRGTKTDSKIEGPERSQEEPKEGETEGEVGT 1440 PFKCTVCRVSYNQSSTLEIHMRSVLHQTRSRGTKTDSKIEGPERSQEEPKEGETEGEVGT Sbjct: 1381 PFKCTVCRVSYNQSSTLEIHMRSVLHQTRSRGTKTDSKIEGPERSQEEPKEGETEGEVGT 1440 Query: 1441 EKKGPDTSGFISGLPFLSPPPPPLDLHRFPAPLFTPPVLPPFPLVPESLLKLQQQQLLLP 1500 EKKGPDTSGFISGLPFLSPPPPPLDLHRFPAPLFTPPVLPPFPLVPESLLKLQQQQLLLP Sbjct: 1441 EKKGPDTSGFISGLPFLSPPPPPLDLHRFPAPLFTPPVLPPFPLVPESLLKLQQQQLLLP 1500 Query: 1501 FYLHDLKVGPKLTLAGPAPVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPSS 1560 FYLHDLKVGPKLTLAGPAPVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPSS Sbjct: 1501 FYLHDLKVGPKLTLAGPAPVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPSS 1560 Query: 1561 PPDPLPNEAARTAAKALLENFGFELVIQYNEGKQAVPPPPTPPPPEALGGGDKLACGACG 1620 PPDPLPNEAARTAAKALLENFGFELVIQYNEGKQAVPPPPTPPPPEALGGGDKLACGACG Sbjct: 1561 PPDPLPNEAARTAAKALLENFGFELVIQYNEGKQAVPPPPTPPPPEALGGGDKLACGACG 1620 Query: 1621 KLFSNMLILKTHEEHVHRRFLPFEALSRYAAQFRKSYDSLYPPLAEPPKPPDGSLDSPVP 1680 KLFSNMLILKTHEEHVHRRFLPFEALSRYAAQFRKSYDSLYPPLAEPPKPPDGSLDSPVP Sbjct: 1621 KLFSNMLILKTHEEHVHRRFLPFEALSRYAAQFRKSYDSLYPPLAEPPKPPDGSLDSPVP 1680 Query: 1681 HLGPPFLVPEPEAGGTRAPEERSRAGGHWPIEEEESSRGNLPPLVPAGRRFSRTKFTEFQ 1740 HLGPPFLVPEPEAGGTRAPEERSRAGGHWPIEEEESSRGNLPPLVPAGRRFSRTKFTEFQ Sbjct: 1681 HLGPPFLVPEPEAGGTRAPEERSRAGGHWPIEEEESSRGNLPPLVPAGRRFSRTKFTEFQ 1740 Query: 1741 TQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARKNACEGGSMPTGGGT 1800 TQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARKNACEGGSMPTGGGT Sbjct: 1741 TQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARKNACEGGSMPTGGGT 1800 Query: 1801 GGASGCRRCHATFSCVFELVRHLKKCYDDQTLEEEEEEAERGEEEEEVEEEEVEEEQGLE 1860 GGASGCRRCHATFSCVFELVRHLKKCYDDQTLEEEEEEAERGEEEEEVEEEEVEEEQGLE Sbjct: 1801 GGASGCRRCHATFSCVFELVRHLKKCYDDQTLEEEEEEAERGEEEEEVEEEEVEEEQGLE 1860 Query: 1861 PPAGPEGPLPEPPDGEELSQAEATKAGGKEPEEKATPSPSPAHTCDQCAISFSSQDLLTS 1920 PPAGPEGPLPEPPDGEELSQAEATKAGGKEPEEKATPSPSPAHTCDQCAISFSSQDLLTS Sbjct: 1861 PPAGPEGPLPEPPDGEELSQAEATKAGGKEPEEKATPSPSPAHTCDQCAISFSSQDLLTS 1920 Query: 1921 HRRLHFLPSLQPSAPPQLLDLPLLVFGERNPLVAATSPMPGPPLKRKHEDGSLSPTGSEA 1980 HRRLHFLPSLQPSAPPQLLDLPLLVFGERNPLVAATSPMPGPPLKRKHEDGSLSPTGSEA Sbjct: 1921 HRRLHFLPSLQPSAPPQLLDLPLLVFGERNPLVAATSPMPGPPLKRKHEDGSLSPTGSEA 1980 Query: 1981 GGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQ 2040 GGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQ Sbjct: 1981 GGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQ 2040 Query: 2041 NTRARERKGQFRSTPGGVPSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAF 2100 NTRARERKGQFRSTPGGVPSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAF Sbjct: 2041 NTRARERKGQFRSTPGGVPSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAF 2100 Query: 2101 PYPTATLASGPQPFLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESEACSLS 2160 PYPTATLASGPQPFLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESEACSLS Sbjct: 2101 PYPTATLASGPQPFLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESEACSLS 2160 Query: 2161 AGDLSDSSASSLAEPESPGAGGTSGGPGGGTGVPDGMGQRRYRTQMSSLQLKIMKACYEA 2220 AGDLSDSSASSLAEPESPGAGGTSGGPGGGTGVPDGMGQRRYRTQMSSLQLKIMKACYEA Sbjct: 2161 AGDLSDSSASSLAEPESPGAGGTSGGPGGGTGVPDGMGQRRYRTQMSSLQLKIMKACYEA 2220 Query: 2221 YRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAKLQGTAAGSTGGSSEGLLAAQRT 2280 YRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAKLQGTAAGSTGGSSEGLLAAQRT Sbjct: 2221 YRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAKLQGTAAGSTGGSSEGLLAAQRT 2280 Query: 2281 DCPYCDVKYDFYVSCRGHLFSRQHLAKLKEAVRAQLKSESKCYDLAPAPEAPPALKAPPA 2340 DCPYCDVKYDFYVSCRGHLFSRQHLAKLKEAVRAQLKSESKCYDLAPAPEAPPALKAPPA Sbjct: 2281 DCPYCDVKYDFYVSCRGHLFSRQHLAKLKEAVRAQLKSESKCYDLAPAPEAPPALKAPPA 2340 Query: 2341 TTPASMPLGAAPTLPRLAPVLLSGPALAQPPLGNLAPFNSGPAASSGLLGLATSVLPTTT 2400 TTPASMPLGAAPTLPRLAPVLLSGPALAQPPLGNLAPFNSGPAASSGLLGLATSVLPTTT Sbjct: 2341 TTPASMPLGAAPTLPRLAPVLLSGPALAQPPLGNLAPFNSGPAASSGLLGLATSVLPTTT 2400 Query: 2401 VVQTAGPGRPLPQRPMPDQTNTSTAGTTDPVPGPPTEPLGDKVSSERKPVAGPTSSSNDA 2460 VVQTAGPGRPLPQRPMPDQTNTSTAGTTDPVPGPPTEPLGDKVSSERKPVAGPTSSSNDA Sbjct: 2401 VVQTAGPGRPLPQRPMPDQTNTSTAGTTDPVPGPPTEPLGDKVSSERKPVAGPTSSSNDA 2460 Query: 2461 LKNLKALKTTVPALLGGQFLPFPLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNP 2520 LKNLKALKTTVPALLGGQFLPFPLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNP Sbjct: 2461 LKNLKALKTTVPALLGGQFLPFPLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNP 2520 Query: 2521 MIPQTLIGLLPNALLQPPPQPPEPTATAPPKPPELPAPGEGEAGEVDELLTGSTGISTVD 2580 MIPQTLIGLLPNALLQPPPQPPEPTATAPPKPPELPAPGEGEAGEVDELLTGSTGISTVD Sbjct: 2521 MIPQTLIGLLPNALLQPPPQPPEPTATAPPKPPELPAPGEGEAGEVDELLTGSTGISTVD 2580 Query: 2581 VTHRYLCRQCKMAFDGEAPATAHQRSFCFFGRGSGGSMPPPLRVPICTYHCLACEVLLSG 2640 VTHRYLCRQCKMAFDGEAPATAHQRSFCFFGRGSGGSMPPPLRVPICTYHCLACEVLLSG Sbjct: 2581 VTHRYLCRQCKMAFDGEAPATAHQRSFCFFGRGSGGSMPPPLRVPICTYHCLACEVLLSG 2640 Query: 2641 REALASHLRSSAHRRKAAPPQGGPPISITNAATAASAAVAFAKEEARLPHTDSNPKTTTT 2700 REALASHLRSSAHRRKAAPPQGGPPISITNAATAASAAVAFAKEEARLPHTDSNPKTTTT Sbjct: 2641 REALASHLRSSAHRRKAAPPQGGPPISITNAATAASAAVAFAKEEARLPHTDSNPKTTTT 2700 Query: 2701 STLLAL 2706 STLLAL Sbjct: 2701 STLLAL 2706 >gi|169207014 PREDICTED: zinc finger homeobox 2 [Homo sapiens] Length = 2706 Score = 5604 bits (14538), Expect = 0.0 Identities = 2706/2706 (100%), Positives = 2706/2706 (100%) Query: 1 MATLNSASTTGTTPSPGHNAPSLPSDTFSSSTPSDPVTKDPPAASSTSENMRSSEPGGQL 60 MATLNSASTTGTTPSPGHNAPSLPSDTFSSSTPSDPVTKDPPAASSTSENMRSSEPGGQL Sbjct: 1 MATLNSASTTGTTPSPGHNAPSLPSDTFSSSTPSDPVTKDPPAASSTSENMRSSEPGGQL 60 Query: 61 LESGCGLVPPKEIGEPQEGPDCGHFPPNDPGVEKDKEQEEEEEGLPPMDLSNHLFFTAGG 120 LESGCGLVPPKEIGEPQEGPDCGHFPPNDPGVEKDKEQEEEEEGLPPMDLSNHLFFTAGG Sbjct: 61 LESGCGLVPPKEIGEPQEGPDCGHFPPNDPGVEKDKEQEEEEEGLPPMDLSNHLFFTAGG 120 Query: 121 EAYLVAKLSLPGGSELLLPKGFPWGEAGIKEEPSLPFLAYPPPSHLTALHIQHGFDPIQG 180 EAYLVAKLSLPGGSELLLPKGFPWGEAGIKEEPSLPFLAYPPPSHLTALHIQHGFDPIQG Sbjct: 121 EAYLVAKLSLPGGSELLLPKGFPWGEAGIKEEPSLPFLAYPPPSHLTALHIQHGFDPIQG 180 Query: 181 FSSSDQILSHDTSAPSPAACEERHGAFWSYQLAPNPPGDPKDGPMGNSGGNHVAVFWLCL 240 FSSSDQILSHDTSAPSPAACEERHGAFWSYQLAPNPPGDPKDGPMGNSGGNHVAVFWLCL Sbjct: 181 FSSSDQILSHDTSAPSPAACEERHGAFWSYQLAPNPPGDPKDGPMGNSGGNHVAVFWLCL 240 Query: 241 LCRLGFSKPQAFMDHTQSHGVKLTPAQYQGLSGSPAVLQEGDEGCKALISFLEPKLPARP 300 LCRLGFSKPQAFMDHTQSHGVKLTPAQYQGLSGSPAVLQEGDEGCKALISFLEPKLPARP Sbjct: 241 LCRLGFSKPQAFMDHTQSHGVKLTPAQYQGLSGSPAVLQEGDEGCKALISFLEPKLPARP 300 Query: 301 SSDIPLDNSSTVNMEANVAQTEDGPPEAEVQALILLDEEVMALSPPSPPTATWDPSPTQA 360 SSDIPLDNSSTVNMEANVAQTEDGPPEAEVQALILLDEEVMALSPPSPPTATWDPSPTQA Sbjct: 301 SSDIPLDNSSTVNMEANVAQTEDGPPEAEVQALILLDEEVMALSPPSPPTATWDPSPTQA 360 Query: 361 KESPVAAGEAGPDWFPEGQEEDGGLCPPLNQSSPTSKEGGTLPAPVGSPEDPSDPPQPYR 420 KESPVAAGEAGPDWFPEGQEEDGGLCPPLNQSSPTSKEGGTLPAPVGSPEDPSDPPQPYR Sbjct: 361 KESPVAAGEAGPDWFPEGQEEDGGLCPPLNQSSPTSKEGGTLPAPVGSPEDPSDPPQPYR 420 Query: 421 LADDYTPAPAAFQGLSLSSHMSLLHSRNSCKTLKCPKCNWHYKYQQTLDVHMREKHPESN 480 LADDYTPAPAAFQGLSLSSHMSLLHSRNSCKTLKCPKCNWHYKYQQTLDVHMREKHPESN Sbjct: 421 LADDYTPAPAAFQGLSLSSHMSLLHSRNSCKTLKCPKCNWHYKYQQTLDVHMREKHPESN 480 Query: 481 SHCSYCSAGGAHPRLARGESYNCGYKPYRCDVCNYSTTTKGNLSIHMQSDKHLANLQGFQ 540 SHCSYCSAGGAHPRLARGESYNCGYKPYRCDVCNYSTTTKGNLSIHMQSDKHLANLQGFQ Sbjct: 481 SHCSYCSAGGAHPRLARGESYNCGYKPYRCDVCNYSTTTKGNLSIHMQSDKHLANLQGFQ 540 Query: 541 AGPGGQGSPPEASLPPSAGDKEPKTKSSWQCKVCSYETNISRNLRIHMTSEKHMQNVLML 600 AGPGGQGSPPEASLPPSAGDKEPKTKSSWQCKVCSYETNISRNLRIHMTSEKHMQNVLML Sbjct: 541 AGPGGQGSPPEASLPPSAGDKEPKTKSSWQCKVCSYETNISRNLRIHMTSEKHMQNVLML 600 Query: 601 HQGLPLGLPPGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRPDKPLEA 660 HQGLPLGLPPGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRPDKPLEA Sbjct: 601 HQGLPLGLPPGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRPDKPLEA 660 Query: 661 QLLLNGFHHVGAPARKFPTSAPGSLSPDAHLPPSQLLGSSSDSLPTSPPPDDSLSLKVFR 720 QLLLNGFHHVGAPARKFPTSAPGSLSPDAHLPPSQLLGSSSDSLPTSPPPDDSLSLKVFR Sbjct: 661 QLLLNGFHHVGAPARKFPTSAPGSLSPDAHLPPSQLLGSSSDSLPTSPPPDDSLSLKVFR 720 Query: 721 CLVCQAFSTDSLELLLYHCSIGRSLPEAEWKEVAGDTHRCKLCCYGTQLKANFQLHLKTD 780 CLVCQAFSTDSLELLLYHCSIGRSLPEAEWKEVAGDTHRCKLCCYGTQLKANFQLHLKTD Sbjct: 721 CLVCQAFSTDSLELLLYHCSIGRSLPEAEWKEVAGDTHRCKLCCYGTQLKANFQLHLKTD 780 Query: 781 KHAQKYQLAAHLREGGGAMGTPSPASLGDGAPYGSVSPLHLRCNICDFESNSKEKMQLHA 840 KHAQKYQLAAHLREGGGAMGTPSPASLGDGAPYGSVSPLHLRCNICDFESNSKEKMQLHA Sbjct: 781 KHAQKYQLAAHLREGGGAMGTPSPASLGDGAPYGSVSPLHLRCNICDFESNSKEKMQLHA 840 Query: 841 RGAAHEENSQIYKVRLGAELGLYHCLLCAWETPSRLAVLQHLRTPAHRDAQAQRRLQLLQ 900 RGAAHEENSQIYKVRLGAELGLYHCLLCAWETPSRLAVLQHLRTPAHRDAQAQRRLQLLQ Sbjct: 841 RGAAHEENSQIYKVRLGAELGLYHCLLCAWETPSRLAVLQHLRTPAHRDAQAQRRLQLLQ 900 Query: 901 NGPTTEEGLAALQSILSFSHGQLRTPAEVVPAEAGNSQPGTIDPEGTGEEPARGCQRLHL 960 NGPTTEEGLAALQSILSFSHGQLRTPAEVVPAEAGNSQPGTIDPEGTGEEPARGCQRLHL Sbjct: 901 NGPTTEEGLAALQSILSFSHGQLRTPAEVVPAEAGNSQPGTIDPEGTGEEPARGCQRLHL 960 Query: 961 KKKKKKKKEWGRASAASKGLCDGGSHPSLTLRPLPICSLQVYCCPYCSFLSPESSQVRAH 1020 KKKKKKKKEWGRASAASKGLCDGGSHPSLTLRPLPICSLQVYCCPYCSFLSPESSQVRAH Sbjct: 961 KKKKKKKKEWGRASAASKGLCDGGSHPSLTLRPLPICSLQVYCCPYCSFLSPESSQVRAH 1020 Query: 1021 TLSQHAVQPKYRCPLCQEQLVGRPALHFHLSHLHNVVPECVEKLLLVVSTGWVRTVQQDL 1080 TLSQHAVQPKYRCPLCQEQLVGRPALHFHLSHLHNVVPECVEKLLLVVSTGWVRTVQQDL Sbjct: 1021 TLSQHAVQPKYRCPLCQEQLVGRPALHFHLSHLHNVVPECVEKLLLVVSTGWVRTVQQDL 1080 Query: 1081 IRAVQEGRKRQGYSGRCMCWGQGAFRQVRVLAGWVRSGIGAVGGGGEATRLFLIAGYNCR 1140 IRAVQEGRKRQGYSGRCMCWGQGAFRQVRVLAGWVRSGIGAVGGGGEATRLFLIAGYNCR Sbjct: 1081 IRAVQEGRKRQGYSGRCMCWGQGAFRQVRVLAGWVRSGIGAVGGGGEATRLFLIAGYNCR 1140 Query: 1141 NDIYNQSAVCTHIKPSGQWPRTPHSWARAYTEQRPGSRKGDSMGQQGLKMTEAKVNCLGI 1200 NDIYNQSAVCTHIKPSGQWPRTPHSWARAYTEQRPGSRKGDSMGQQGLKMTEAKVNCLGI Sbjct: 1141 NDIYNQSAVCTHIKPSGQWPRTPHSWARAYTEQRPGSRKGDSMGQQGLKMTEAKVNCLGI 1200 Query: 1201 EWVGSGLNEVPSSLYFLLSPLEGPNLTPEASPDPLPEPPLASVEVPDKPSGSPGQPPSPA 1260 EWVGSGLNEVPSSLYFLLSPLEGPNLTPEASPDPLPEPPLASVEVPDKPSGSPGQPPSPA Sbjct: 1201 EWVGSGLNEVPSSLYFLLSPLEGPNLTPEASPDPLPEPPLASVEVPDKPSGSPGQPPSPA 1260 Query: 1261 PSPVPEPDAQAEDVAPPPTMAEEEEGTTGELRSAEPAPADSRHPLTYRKTTNFALDKFLD 1320 PSPVPEPDAQAEDVAPPPTMAEEEEGTTGELRSAEPAPADSRHPLTYRKTTNFALDKFLD Sbjct: 1261 PSPVPEPDAQAEDVAPPPTMAEEEEGTTGELRSAEPAPADSRHPLTYRKTTNFALDKFLD 1320 Query: 1321 PARPYKCTVCKESFTQKNILLVHYNSVSHLHKMKKAAIDPSAPARGEAGAPPTTTAATDK 1380 PARPYKCTVCKESFTQKNILLVHYNSVSHLHKMKKAAIDPSAPARGEAGAPPTTTAATDK Sbjct: 1321 PARPYKCTVCKESFTQKNILLVHYNSVSHLHKMKKAAIDPSAPARGEAGAPPTTTAATDK 1380 Query: 1381 PFKCTVCRVSYNQSSTLEIHMRSVLHQTRSRGTKTDSKIEGPERSQEEPKEGETEGEVGT 1440 PFKCTVCRVSYNQSSTLEIHMRSVLHQTRSRGTKTDSKIEGPERSQEEPKEGETEGEVGT Sbjct: 1381 PFKCTVCRVSYNQSSTLEIHMRSVLHQTRSRGTKTDSKIEGPERSQEEPKEGETEGEVGT 1440 Query: 1441 EKKGPDTSGFISGLPFLSPPPPPLDLHRFPAPLFTPPVLPPFPLVPESLLKLQQQQLLLP 1500 EKKGPDTSGFISGLPFLSPPPPPLDLHRFPAPLFTPPVLPPFPLVPESLLKLQQQQLLLP Sbjct: 1441 EKKGPDTSGFISGLPFLSPPPPPLDLHRFPAPLFTPPVLPPFPLVPESLLKLQQQQLLLP 1500 Query: 1501 FYLHDLKVGPKLTLAGPAPVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPSS 1560 FYLHDLKVGPKLTLAGPAPVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPSS Sbjct: 1501 FYLHDLKVGPKLTLAGPAPVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPSS 1560 Query: 1561 PPDPLPNEAARTAAKALLENFGFELVIQYNEGKQAVPPPPTPPPPEALGGGDKLACGACG 1620 PPDPLPNEAARTAAKALLENFGFELVIQYNEGKQAVPPPPTPPPPEALGGGDKLACGACG Sbjct: 1561 PPDPLPNEAARTAAKALLENFGFELVIQYNEGKQAVPPPPTPPPPEALGGGDKLACGACG 1620 Query: 1621 KLFSNMLILKTHEEHVHRRFLPFEALSRYAAQFRKSYDSLYPPLAEPPKPPDGSLDSPVP 1680 KLFSNMLILKTHEEHVHRRFLPFEALSRYAAQFRKSYDSLYPPLAEPPKPPDGSLDSPVP Sbjct: 1621 KLFSNMLILKTHEEHVHRRFLPFEALSRYAAQFRKSYDSLYPPLAEPPKPPDGSLDSPVP 1680 Query: 1681 HLGPPFLVPEPEAGGTRAPEERSRAGGHWPIEEEESSRGNLPPLVPAGRRFSRTKFTEFQ 1740 HLGPPFLVPEPEAGGTRAPEERSRAGGHWPIEEEESSRGNLPPLVPAGRRFSRTKFTEFQ Sbjct: 1681 HLGPPFLVPEPEAGGTRAPEERSRAGGHWPIEEEESSRGNLPPLVPAGRRFSRTKFTEFQ 1740 Query: 1741 TQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARKNACEGGSMPTGGGT 1800 TQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARKNACEGGSMPTGGGT Sbjct: 1741 TQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARKNACEGGSMPTGGGT 1800 Query: 1801 GGASGCRRCHATFSCVFELVRHLKKCYDDQTLEEEEEEAERGEEEEEVEEEEVEEEQGLE 1860 GGASGCRRCHATFSCVFELVRHLKKCYDDQTLEEEEEEAERGEEEEEVEEEEVEEEQGLE Sbjct: 1801 GGASGCRRCHATFSCVFELVRHLKKCYDDQTLEEEEEEAERGEEEEEVEEEEVEEEQGLE 1860 Query: 1861 PPAGPEGPLPEPPDGEELSQAEATKAGGKEPEEKATPSPSPAHTCDQCAISFSSQDLLTS 1920 PPAGPEGPLPEPPDGEELSQAEATKAGGKEPEEKATPSPSPAHTCDQCAISFSSQDLLTS Sbjct: 1861 PPAGPEGPLPEPPDGEELSQAEATKAGGKEPEEKATPSPSPAHTCDQCAISFSSQDLLTS 1920 Query: 1921 HRRLHFLPSLQPSAPPQLLDLPLLVFGERNPLVAATSPMPGPPLKRKHEDGSLSPTGSEA 1980 HRRLHFLPSLQPSAPPQLLDLPLLVFGERNPLVAATSPMPGPPLKRKHEDGSLSPTGSEA Sbjct: 1921 HRRLHFLPSLQPSAPPQLLDLPLLVFGERNPLVAATSPMPGPPLKRKHEDGSLSPTGSEA 1980 Query: 1981 GGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQ 2040 GGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQ Sbjct: 1981 GGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQ 2040 Query: 2041 NTRARERKGQFRSTPGGVPSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAF 2100 NTRARERKGQFRSTPGGVPSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAF Sbjct: 2041 NTRARERKGQFRSTPGGVPSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAF 2100 Query: 2101 PYPTATLASGPQPFLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESEACSLS 2160 PYPTATLASGPQPFLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESEACSLS Sbjct: 2101 PYPTATLASGPQPFLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESEACSLS 2160 Query: 2161 AGDLSDSSASSLAEPESPGAGGTSGGPGGGTGVPDGMGQRRYRTQMSSLQLKIMKACYEA 2220 AGDLSDSSASSLAEPESPGAGGTSGGPGGGTGVPDGMGQRRYRTQMSSLQLKIMKACYEA Sbjct: 2161 AGDLSDSSASSLAEPESPGAGGTSGGPGGGTGVPDGMGQRRYRTQMSSLQLKIMKACYEA 2220 Query: 2221 YRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAKLQGTAAGSTGGSSEGLLAAQRT 2280 YRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAKLQGTAAGSTGGSSEGLLAAQRT Sbjct: 2221 YRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAKLQGTAAGSTGGSSEGLLAAQRT 2280 Query: 2281 DCPYCDVKYDFYVSCRGHLFSRQHLAKLKEAVRAQLKSESKCYDLAPAPEAPPALKAPPA 2340 DCPYCDVKYDFYVSCRGHLFSRQHLAKLKEAVRAQLKSESKCYDLAPAPEAPPALKAPPA Sbjct: 2281 DCPYCDVKYDFYVSCRGHLFSRQHLAKLKEAVRAQLKSESKCYDLAPAPEAPPALKAPPA 2340 Query: 2341 TTPASMPLGAAPTLPRLAPVLLSGPALAQPPLGNLAPFNSGPAASSGLLGLATSVLPTTT 2400 TTPASMPLGAAPTLPRLAPVLLSGPALAQPPLGNLAPFNSGPAASSGLLGLATSVLPTTT Sbjct: 2341 TTPASMPLGAAPTLPRLAPVLLSGPALAQPPLGNLAPFNSGPAASSGLLGLATSVLPTTT 2400 Query: 2401 VVQTAGPGRPLPQRPMPDQTNTSTAGTTDPVPGPPTEPLGDKVSSERKPVAGPTSSSNDA 2460 VVQTAGPGRPLPQRPMPDQTNTSTAGTTDPVPGPPTEPLGDKVSSERKPVAGPTSSSNDA Sbjct: 2401 VVQTAGPGRPLPQRPMPDQTNTSTAGTTDPVPGPPTEPLGDKVSSERKPVAGPTSSSNDA 2460 Query: 2461 LKNLKALKTTVPALLGGQFLPFPLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNP 2520 LKNLKALKTTVPALLGGQFLPFPLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNP Sbjct: 2461 LKNLKALKTTVPALLGGQFLPFPLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNP 2520 Query: 2521 MIPQTLIGLLPNALLQPPPQPPEPTATAPPKPPELPAPGEGEAGEVDELLTGSTGISTVD 2580 MIPQTLIGLLPNALLQPPPQPPEPTATAPPKPPELPAPGEGEAGEVDELLTGSTGISTVD Sbjct: 2521 MIPQTLIGLLPNALLQPPPQPPEPTATAPPKPPELPAPGEGEAGEVDELLTGSTGISTVD 2580 Query: 2581 VTHRYLCRQCKMAFDGEAPATAHQRSFCFFGRGSGGSMPPPLRVPICTYHCLACEVLLSG 2640 VTHRYLCRQCKMAFDGEAPATAHQRSFCFFGRGSGGSMPPPLRVPICTYHCLACEVLLSG Sbjct: 2581 VTHRYLCRQCKMAFDGEAPATAHQRSFCFFGRGSGGSMPPPLRVPICTYHCLACEVLLSG 2640 Query: 2641 REALASHLRSSAHRRKAAPPQGGPPISITNAATAASAAVAFAKEEARLPHTDSNPKTTTT 2700 REALASHLRSSAHRRKAAPPQGGPPISITNAATAASAAVAFAKEEARLPHTDSNPKTTTT Sbjct: 2641 REALASHLRSSAHRRKAAPPQGGPPISITNAATAASAAVAFAKEEARLPHTDSNPKTTTT 2700 Query: 2701 STLLAL 2706 STLLAL Sbjct: 2701 STLLAL 2706 >gi|169207217 PREDICTED: zinc finger homeobox 2 [Homo sapiens] Length = 2790 Score = 5598 bits (14522), Expect = 0.0 Identities = 2704/2706 (99%), Positives = 2704/2706 (99%) Query: 1 MATLNSASTTGTTPSPGHNAPSLPSDTFSSSTPSDPVTKDPPAASSTSENMRSSEPGGQL 60 MATLNSASTTGTTPSPGHNAPSLPSDTFSSSTPSD VTKDPPAASSTSENMRSSEPGGQL Sbjct: 85 MATLNSASTTGTTPSPGHNAPSLPSDTFSSSTPSDSVTKDPPAASSTSENMRSSEPGGQL 144 Query: 61 LESGCGLVPPKEIGEPQEGPDCGHFPPNDPGVEKDKEQEEEEEGLPPMDLSNHLFFTAGG 120 LESGCGLVPPKEIGEPQEGPDCGHFPPNDPGVEKDKEQEEEEEGLPPMDLSNHLFFTAGG Sbjct: 145 LESGCGLVPPKEIGEPQEGPDCGHFPPNDPGVEKDKEQEEEEEGLPPMDLSNHLFFTAGG 204 Query: 121 EAYLVAKLSLPGGSELLLPKGFPWGEAGIKEEPSLPFLAYPPPSHLTALHIQHGFDPIQG 180 EAYLVAKLSLPGGSELLLPKGFPWGEAGIKEEPSLPFLAYPPPSHLTALHIQHGFDPIQG Sbjct: 205 EAYLVAKLSLPGGSELLLPKGFPWGEAGIKEEPSLPFLAYPPPSHLTALHIQHGFDPIQG 264 Query: 181 FSSSDQILSHDTSAPSPAACEERHGAFWSYQLAPNPPGDPKDGPMGNSGGNHVAVFWLCL 240 FSSSDQILSHDTSAPSPAACEERHGAFWSYQLAPNPPGDPKDGPMGNSGGNHVAVFWLCL Sbjct: 265 FSSSDQILSHDTSAPSPAACEERHGAFWSYQLAPNPPGDPKDGPMGNSGGNHVAVFWLCL 324 Query: 241 LCRLGFSKPQAFMDHTQSHGVKLTPAQYQGLSGSPAVLQEGDEGCKALISFLEPKLPARP 300 LCRLGFSKPQAFMDHTQSHGVKLTPAQYQGLSGSPAVLQEGDEGCKALISFLEPKLPARP Sbjct: 325 LCRLGFSKPQAFMDHTQSHGVKLTPAQYQGLSGSPAVLQEGDEGCKALISFLEPKLPARP 384 Query: 301 SSDIPLDNSSTVNMEANVAQTEDGPPEAEVQALILLDEEVMALSPPSPPTATWDPSPTQA 360 SSDIPLDNSSTVNMEANVAQTEDGPPEAEVQALILLDEEVMALSPPSPPTATWDPSPTQA Sbjct: 385 SSDIPLDNSSTVNMEANVAQTEDGPPEAEVQALILLDEEVMALSPPSPPTATWDPSPTQA 444 Query: 361 KESPVAAGEAGPDWFPEGQEEDGGLCPPLNQSSPTSKEGGTLPAPVGSPEDPSDPPQPYR 420 KESPVAAGEAGPDWFPEGQEEDGGLCPPLNQSSPTSKEGGTLPAPVGSPEDPSDPPQPYR Sbjct: 445 KESPVAAGEAGPDWFPEGQEEDGGLCPPLNQSSPTSKEGGTLPAPVGSPEDPSDPPQPYR 504 Query: 421 LADDYTPAPAAFQGLSLSSHMSLLHSRNSCKTLKCPKCNWHYKYQQTLDVHMREKHPESN 480 LADDYTPAPAAFQGLSLSSHMSLLHSRNSCKTLKCPKCNWHYKYQQTLDVHMREKHPESN Sbjct: 505 LADDYTPAPAAFQGLSLSSHMSLLHSRNSCKTLKCPKCNWHYKYQQTLDVHMREKHPESN 564 Query: 481 SHCSYCSAGGAHPRLARGESYNCGYKPYRCDVCNYSTTTKGNLSIHMQSDKHLANLQGFQ 540 SHCSYCSAGGAHPRLARGESYNCGYKPYRCDVCNYSTTTKGNLSIHMQSDKHLANLQGFQ Sbjct: 565 SHCSYCSAGGAHPRLARGESYNCGYKPYRCDVCNYSTTTKGNLSIHMQSDKHLANLQGFQ 624 Query: 541 AGPGGQGSPPEASLPPSAGDKEPKTKSSWQCKVCSYETNISRNLRIHMTSEKHMQNVLML 600 AGPGGQGSP EASLPPSAGDKEPKTKSSWQCKVCSYETNISRNLRIHMTSEKHMQNVLML Sbjct: 625 AGPGGQGSPTEASLPPSAGDKEPKTKSSWQCKVCSYETNISRNLRIHMTSEKHMQNVLML 684 Query: 601 HQGLPLGLPPGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRPDKPLEA 660 HQGLPLGLPPGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRPDKPLEA Sbjct: 685 HQGLPLGLPPGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRPDKPLEA 744 Query: 661 QLLLNGFHHVGAPARKFPTSAPGSLSPDAHLPPSQLLGSSSDSLPTSPPPDDSLSLKVFR 720 QLLLNGFHHVGAPARKFPTSAPGSLSPDAHLPPSQLLGSSSDSLPTSPPPDDSLSLKVFR Sbjct: 745 QLLLNGFHHVGAPARKFPTSAPGSLSPDAHLPPSQLLGSSSDSLPTSPPPDDSLSLKVFR 804 Query: 721 CLVCQAFSTDSLELLLYHCSIGRSLPEAEWKEVAGDTHRCKLCCYGTQLKANFQLHLKTD 780 CLVCQAFSTDSLELLLYHCSIGRSLPEAEWKEVAGDTHRCKLCCYGTQLKANFQLHLKTD Sbjct: 805 CLVCQAFSTDSLELLLYHCSIGRSLPEAEWKEVAGDTHRCKLCCYGTQLKANFQLHLKTD 864 Query: 781 KHAQKYQLAAHLREGGGAMGTPSPASLGDGAPYGSVSPLHLRCNICDFESNSKEKMQLHA 840 KHAQKYQLAAHLREGGGAMGTPSPASLGDGAPYGSVSPLHLRCNICDFESNSKEKMQLHA Sbjct: 865 KHAQKYQLAAHLREGGGAMGTPSPASLGDGAPYGSVSPLHLRCNICDFESNSKEKMQLHA 924 Query: 841 RGAAHEENSQIYKVRLGAELGLYHCLLCAWETPSRLAVLQHLRTPAHRDAQAQRRLQLLQ 900 RGAAHEENSQIYKVRLGAELGLYHCLLCAWETPSRLAVLQHLRTPAHRDAQAQRRLQLLQ Sbjct: 925 RGAAHEENSQIYKVRLGAELGLYHCLLCAWETPSRLAVLQHLRTPAHRDAQAQRRLQLLQ 984 Query: 901 NGPTTEEGLAALQSILSFSHGQLRTPAEVVPAEAGNSQPGTIDPEGTGEEPARGCQRLHL 960 NGPTTEEGLAALQSILSFSHGQLRTPAEVVPAEAGNSQPGTIDPEGTGEEPARGCQRLHL Sbjct: 985 NGPTTEEGLAALQSILSFSHGQLRTPAEVVPAEAGNSQPGTIDPEGTGEEPARGCQRLHL 1044 Query: 961 KKKKKKKKEWGRASAASKGLCDGGSHPSLTLRPLPICSLQVYCCPYCSFLSPESSQVRAH 1020 KKKKKKKKEWGRASAASKGLCDGGSHPSLTLRPLPICSLQVYCCPYCSFLSPESSQVRAH Sbjct: 1045 KKKKKKKKEWGRASAASKGLCDGGSHPSLTLRPLPICSLQVYCCPYCSFLSPESSQVRAH 1104 Query: 1021 TLSQHAVQPKYRCPLCQEQLVGRPALHFHLSHLHNVVPECVEKLLLVVSTGWVRTVQQDL 1080 TLSQHAVQPKYRCPLCQEQLVGRPALHFHLSHLHNVVPECVEKLLLVVSTGWVRTVQQDL Sbjct: 1105 TLSQHAVQPKYRCPLCQEQLVGRPALHFHLSHLHNVVPECVEKLLLVVSTGWVRTVQQDL 1164 Query: 1081 IRAVQEGRKRQGYSGRCMCWGQGAFRQVRVLAGWVRSGIGAVGGGGEATRLFLIAGYNCR 1140 IRAVQEGRKRQGYSGRCMCWGQGAFRQVRVLAGWVRSGIGAVGGGGEATRLFLIAGYNCR Sbjct: 1165 IRAVQEGRKRQGYSGRCMCWGQGAFRQVRVLAGWVRSGIGAVGGGGEATRLFLIAGYNCR 1224 Query: 1141 NDIYNQSAVCTHIKPSGQWPRTPHSWARAYTEQRPGSRKGDSMGQQGLKMTEAKVNCLGI 1200 NDIYNQSAVCTHIKPSGQWPRTPHSWARAYTEQRPGSRKGDSMGQQGLKMTEAKVNCLGI Sbjct: 1225 NDIYNQSAVCTHIKPSGQWPRTPHSWARAYTEQRPGSRKGDSMGQQGLKMTEAKVNCLGI 1284 Query: 1201 EWVGSGLNEVPSSLYFLLSPLEGPNLTPEASPDPLPEPPLASVEVPDKPSGSPGQPPSPA 1260 EWVGSGLNEVPSSLYFLLSPLEGPNLTPEASPDPLPEPPLASVEVPDKPSGSPGQPPSPA Sbjct: 1285 EWVGSGLNEVPSSLYFLLSPLEGPNLTPEASPDPLPEPPLASVEVPDKPSGSPGQPPSPA 1344 Query: 1261 PSPVPEPDAQAEDVAPPPTMAEEEEGTTGELRSAEPAPADSRHPLTYRKTTNFALDKFLD 1320 PSPVPEPDAQAEDVAPPPTMAEEEEGTTGELRSAEPAPADSRHPLTYRKTTNFALDKFLD Sbjct: 1345 PSPVPEPDAQAEDVAPPPTMAEEEEGTTGELRSAEPAPADSRHPLTYRKTTNFALDKFLD 1404 Query: 1321 PARPYKCTVCKESFTQKNILLVHYNSVSHLHKMKKAAIDPSAPARGEAGAPPTTTAATDK 1380 PARPYKCTVCKESFTQKNILLVHYNSVSHLHKMKKAAIDPSAPARGEAGAPPTTTAATDK Sbjct: 1405 PARPYKCTVCKESFTQKNILLVHYNSVSHLHKMKKAAIDPSAPARGEAGAPPTTTAATDK 1464 Query: 1381 PFKCTVCRVSYNQSSTLEIHMRSVLHQTRSRGTKTDSKIEGPERSQEEPKEGETEGEVGT 1440 PFKCTVCRVSYNQSSTLEIHMRSVLHQTRSRGTKTDSKIEGPERSQEEPKEGETEGEVGT Sbjct: 1465 PFKCTVCRVSYNQSSTLEIHMRSVLHQTRSRGTKTDSKIEGPERSQEEPKEGETEGEVGT 1524 Query: 1441 EKKGPDTSGFISGLPFLSPPPPPLDLHRFPAPLFTPPVLPPFPLVPESLLKLQQQQLLLP 1500 EKKGPDTSGFISGLPFLSPPPPPLDLHRFPAPLFTPPVLPPFPLVPESLLKLQQQQLLLP Sbjct: 1525 EKKGPDTSGFISGLPFLSPPPPPLDLHRFPAPLFTPPVLPPFPLVPESLLKLQQQQLLLP 1584 Query: 1501 FYLHDLKVGPKLTLAGPAPVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPSS 1560 FYLHDLKVGPKLTLAGPAPVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPSS Sbjct: 1585 FYLHDLKVGPKLTLAGPAPVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPSS 1644 Query: 1561 PPDPLPNEAARTAAKALLENFGFELVIQYNEGKQAVPPPPTPPPPEALGGGDKLACGACG 1620 PPDPLPNEAARTAAKALLENFGFELVIQYNEGKQAVPPPPTPPPPEALGGGDKLACGACG Sbjct: 1645 PPDPLPNEAARTAAKALLENFGFELVIQYNEGKQAVPPPPTPPPPEALGGGDKLACGACG 1704 Query: 1621 KLFSNMLILKTHEEHVHRRFLPFEALSRYAAQFRKSYDSLYPPLAEPPKPPDGSLDSPVP 1680 KLFSNMLILKTHEEHVHRRFLPFEALSRYAAQFRKSYDSLYPPLAEPPKPPDGSLDSPVP Sbjct: 1705 KLFSNMLILKTHEEHVHRRFLPFEALSRYAAQFRKSYDSLYPPLAEPPKPPDGSLDSPVP 1764 Query: 1681 HLGPPFLVPEPEAGGTRAPEERSRAGGHWPIEEEESSRGNLPPLVPAGRRFSRTKFTEFQ 1740 HLGPPFLVPEPEAGGTRAPEERSRAGGHWPIEEEESSRGNLPPLVPAGRRFSRTKFTEFQ Sbjct: 1765 HLGPPFLVPEPEAGGTRAPEERSRAGGHWPIEEEESSRGNLPPLVPAGRRFSRTKFTEFQ 1824 Query: 1741 TQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARKNACEGGSMPTGGGT 1800 TQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARKNACEGGSMPTGGGT Sbjct: 1825 TQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARKNACEGGSMPTGGGT 1884 Query: 1801 GGASGCRRCHATFSCVFELVRHLKKCYDDQTLEEEEEEAERGEEEEEVEEEEVEEEQGLE 1860 GGASGCRRCHATFSCVFELVRHLKKCYDDQTLEEEEEEAERGEEEEEVEEEEVEEEQGLE Sbjct: 1885 GGASGCRRCHATFSCVFELVRHLKKCYDDQTLEEEEEEAERGEEEEEVEEEEVEEEQGLE 1944 Query: 1861 PPAGPEGPLPEPPDGEELSQAEATKAGGKEPEEKATPSPSPAHTCDQCAISFSSQDLLTS 1920 PPAGPEGPLPEPPDGEELSQAEATKAGGKEPEEKATPSPSPAHTCDQCAISFSSQDLLTS Sbjct: 1945 PPAGPEGPLPEPPDGEELSQAEATKAGGKEPEEKATPSPSPAHTCDQCAISFSSQDLLTS 2004 Query: 1921 HRRLHFLPSLQPSAPPQLLDLPLLVFGERNPLVAATSPMPGPPLKRKHEDGSLSPTGSEA 1980 HRRLHFLPSLQPSAPPQLLDLPLLVFGERNPLVAATSPMPGPPLKRKHEDGSLSPTGSEA Sbjct: 2005 HRRLHFLPSLQPSAPPQLLDLPLLVFGERNPLVAATSPMPGPPLKRKHEDGSLSPTGSEA 2064 Query: 1981 GGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQ 2040 GGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQ Sbjct: 2065 GGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQ 2124 Query: 2041 NTRARERKGQFRSTPGGVPSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAF 2100 NTRARERKGQFRSTPGGVPSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAF Sbjct: 2125 NTRARERKGQFRSTPGGVPSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAF 2184 Query: 2101 PYPTATLASGPQPFLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESEACSLS 2160 PYPTATLASGPQPFLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESEACSLS Sbjct: 2185 PYPTATLASGPQPFLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESEACSLS 2244 Query: 2161 AGDLSDSSASSLAEPESPGAGGTSGGPGGGTGVPDGMGQRRYRTQMSSLQLKIMKACYEA 2220 AGDLSDSSASSLAEPESPGAGGTSGGPGGGTGVPDGMGQRRYRTQMSSLQLKIMKACYEA Sbjct: 2245 AGDLSDSSASSLAEPESPGAGGTSGGPGGGTGVPDGMGQRRYRTQMSSLQLKIMKACYEA 2304 Query: 2221 YRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAKLQGTAAGSTGGSSEGLLAAQRT 2280 YRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAKLQGTAAGSTGGSSEGLLAAQRT Sbjct: 2305 YRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAKLQGTAAGSTGGSSEGLLAAQRT 2364 Query: 2281 DCPYCDVKYDFYVSCRGHLFSRQHLAKLKEAVRAQLKSESKCYDLAPAPEAPPALKAPPA 2340 DCPYCDVKYDFYVSCRGHLFSRQHLAKLKEAVRAQLKSESKCYDLAPAPEAPPALKAPPA Sbjct: 2365 DCPYCDVKYDFYVSCRGHLFSRQHLAKLKEAVRAQLKSESKCYDLAPAPEAPPALKAPPA 2424 Query: 2341 TTPASMPLGAAPTLPRLAPVLLSGPALAQPPLGNLAPFNSGPAASSGLLGLATSVLPTTT 2400 TTPASMPLGAAPTLPRLAPVLLSGPALAQPPLGNLAPFNSGPAASSGLLGLATSVLPTTT Sbjct: 2425 TTPASMPLGAAPTLPRLAPVLLSGPALAQPPLGNLAPFNSGPAASSGLLGLATSVLPTTT 2484 Query: 2401 VVQTAGPGRPLPQRPMPDQTNTSTAGTTDPVPGPPTEPLGDKVSSERKPVAGPTSSSNDA 2460 VVQTAGPGRPLPQRPMPDQTNTSTAGTTDPVPGPPTEPLGDKVSSERKPVAGPTSSSNDA Sbjct: 2485 VVQTAGPGRPLPQRPMPDQTNTSTAGTTDPVPGPPTEPLGDKVSSERKPVAGPTSSSNDA 2544 Query: 2461 LKNLKALKTTVPALLGGQFLPFPLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNP 2520 LKNLKALKTTVPALLGGQFLPFPLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNP Sbjct: 2545 LKNLKALKTTVPALLGGQFLPFPLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNP 2604 Query: 2521 MIPQTLIGLLPNALLQPPPQPPEPTATAPPKPPELPAPGEGEAGEVDELLTGSTGISTVD 2580 MIPQTLIGLLPNALLQPPPQPPEPTATAPPKPPELPAPGEGEAGEVDELLTGSTGISTVD Sbjct: 2605 MIPQTLIGLLPNALLQPPPQPPEPTATAPPKPPELPAPGEGEAGEVDELLTGSTGISTVD 2664 Query: 2581 VTHRYLCRQCKMAFDGEAPATAHQRSFCFFGRGSGGSMPPPLRVPICTYHCLACEVLLSG 2640 VTHRYLCRQCKMAFDGEAPATAHQRSFCFFGRGSGGSMPPPLRVPICTYHCLACEVLLSG Sbjct: 2665 VTHRYLCRQCKMAFDGEAPATAHQRSFCFFGRGSGGSMPPPLRVPICTYHCLACEVLLSG 2724 Query: 2641 REALASHLRSSAHRRKAAPPQGGPPISITNAATAASAAVAFAKEEARLPHTDSNPKTTTT 2700 REALASHLRSSAHRRKAAPPQGGPPISITNAATAASAAVAFAKEEARLPHTDSNPKTTTT Sbjct: 2725 REALASHLRSSAHRRKAAPPQGGPPISITNAATAASAAVAFAKEEARLPHTDSNPKTTTT 2784 Query: 2701 STLLAL 2706 STLLAL Sbjct: 2785 STLLAL 2790 >gi|118498345 AT-binding transcription factor 1 [Homo sapiens] Length = 3703 Score = 531 bits (1369), Expect = e-150 Identities = 325/851 (38%), Positives = 455/851 (53%), Gaps = 103/851 (12%) Query: 279 QEGDEGCKALI-SFLEPKLPARPSSD--IPLDNSSTVNMEANVAQTEDGPPEAEVQALIL 335 +E DEGCK L S L+ +L RP + +SS ++ + + P L Sbjct: 485 EEEDEGCKGLFPSELDEELEDRPHEEPGAAAGSSSKKDLALSNQSISNSP---------L 535 Query: 336 LDEEVMALSPPSPPTATWDPSP----------------TQAKESPVAAGEAGPDWFPEGQ 379 + + LS + T++ S ++ + VA G D+ E Sbjct: 536 MPNVLQTLSRGTASTSSNSASSFVVFDGANRRNRLSFNSEGVRANVAEGGRRLDFADESA 595 Query: 380 EEDGGLCPPLNQSSPTSKEGGTLP--------APVGSPEDPSDPPQPYRLADDYTPAPAA 431 +D P N+S+ +GG +P +G E PS D + Sbjct: 596 NKDNATAPEPNESTE-GDDGGFVPHHQHAGSLCELGVGECPSGSGVECPKCDTVLGSSR- 653 Query: 432 FQGLSLSSHMSLLHSRNSCKTLKCPKCNWHYKYQQTLDVHMREKHPESNSHCSYCSAGGA 491 SL HM+++HSRNSCKTLKCPKCNWHYKYQQTL+ HM+EKHPE C YC +G Sbjct: 654 ----SLGGHMTMMHSRNSCKTLKCPKCNWHYKYQQTLEAHMKEKHPEPGGSCVYCKSGQP 709 Query: 492 HPRLARGESYNCGYKPYRCDVCNYSTTTKGNLSIHMQSDKHLANLQGFQAGPGGQ----- 546 HPRLARGESY CGYKP+RC+VCNYSTTTKGNLSIHMQSDKHL N+Q Q G G Q Sbjct: 710 HPRLARGESYTCGYKPFRCEVCNYSTTTKGNLSIHMQSDKHLNNMQNLQNGGGEQVFSHT 769 Query: 547 ---------GSPPEASLPPSAG---DKEPKTKSSWQCKVCSYETNISRNLRIHMTSEKHM 594 + A++ S G +PKTK +W+C+VC YETN++RNLRIHMTSEKHM Sbjct: 770 AGAAAAAVAAAAAAANISSSCGAPSPTKPKTKPTWRCEVCDYETNVARNLRIHMTSEKHM 829 Query: 595 QNVLMLHQGLPLGLPPGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRP 654 N+++L Q + +G G P P + EL+QY+ Q + P + Sbjct: 830 HNMMLLQQNMTQIQHNRHLGLGSLPSP-----AEAELYQYYLAQNMNLPNLKM------D 878 Query: 655 DKPLEAQLLLNGFH--HVGAPARKFPTSAPGSLSPDAHLPPSQLLGSSSDSLPTSPPPDD 712 +AQ +++GF G A P G + D L QL+ +L S + Sbjct: 879 SAASDAQFMMSGFQLDPAGPMAAMTPALVGGEIPLDMRLGGGQLVSEELMNLGESFIQTN 938 Query: 713 SLSLKVFRCLVCQAFSTDSLELLLYHCSIGRSLPEAEWKEVAGDTHRCKLCCYGTQLKAN 772 SLK+F+C VC F+TD+L++L H ++ RSL E EWK V GD+++CKLC Y TQLKAN Sbjct: 939 DPSLKLFQCAVCNKFTTDNLDMLGLHMNVERSLSEDEWKAVMGDSYQCKLCRYNTQLKAN 998 Query: 773 FQLHLKTDKHAQKYQLAAHLREGGGA-MGTPSPASLGDGAPYGSVSPLHLRCNICDFESN 831 FQLH KTDKH QKYQL AH++EGG A ++G +P+HL+CN CD+ +N Sbjct: 999 FQLHCKTDKHVQKYQLVAHIKEGGKANEWRLKCVAIG--------NPVHLKCNACDYYTN 1050 Query: 832 SKEKMQLHARGAAHEENSQIYKVRLGAELGL------YHCLLCAWETPSRLAVLQHLRTP 885 S EK++LH + HE + ++YK E G+ YHC+LC + T ++L ++QH+R+ Sbjct: 1051 SLEKLRLHTVNSRHEASLKLYKHLQQHESGVEGESCYYHCVLCNYSTKAKLNLIQHVRSM 1110 Query: 886 AHRDAQAQRRLQLLQNG-PTTEEGLAALQSILSFSHGQLRTPAEVVPAEAGNSQPGTIDP 944 H+ +++ R+LQ LQ G P +E L I + P E + G S+ DP Sbjct: 1111 KHQRSESLRKLQRLQKGLPEEDEDLG---QIFTIRRCPSTDPEEAIEDVEGPSETAA-DP 1166 Query: 945 EGTGEEPARGCQRLHLKKKKKKKKEWGRASAASKGLCDGGS--HPSLTLRPL---PICSL 999 E ++ G + +KE + A SK + GS P + RP I Sbjct: 1167 EELAKDQEGGA------SSSQAEKELTDSPATSKRISFPGSSESPLSSKRPKTAEEIKPE 1220 Query: 1000 QVYCCPYCSFLSPESSQVRAHTLSQHAVQPKYRCPLCQEQLVGRPALHFHLSHLHNVVPE 1059 Q+Y CPYC + + + +++R H ++QH+VQP RCPLCQ+ L + L HL+HLH+V P+ Sbjct: 1221 QMYQCPYCKYSNADVNRLRVHAMTQHSVQPMLRCPLCQDMLNNKIHLQLHLTHLHSVAPD 1280 Query: 1060 CVEKLLLVVST 1070 CVEKL++ V+T Sbjct: 1281 CVEKLIMTVTT 1291 Score = 256 bits (655), Expect = 2e-67 Identities = 214/705 (30%), Positives = 297/705 (42%), Gaps = 192/705 (27%) Query: 2162 GDLSDSSASSLAEPESPGAGGT-SGGPGGGTGVPDGMGQRRYRTQMSSLQLKIMKACYEA 2220 G + S SSLA+P SP G + S G G +G D GQ+R+RTQM++LQLK++K+C+ Sbjct: 2910 GTVDYSETSSLADPCSPSPGASGSAGKSGDSG--DRPGQKRFRTQMTNLQLKVLKSCFND 2967 Query: 2221 YRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAKLQGTAAGSTGGSSEGLLAAQRT 2280 YRTPTM ECEVLG +IGLPKRV+QVWFQNARAKEKK+KL + G ++ +T Sbjct: 2968 YRTPTMLECEVLGNDIGLPKRVVQVWFQNARAKEKKSKL---SMAKHFGINQTSYEGPKT 3024 Query: 2281 DCPYCDVKYDFYVSCRGHLFSRQHLAKLKEAVRAQLKSESKCYD------LAPAPEAPPA 2334 +C C +KY +S R H+FS+QH++K+K+ + +QL E + +D L E Sbjct: 3025 ECTLCGIKYSARLSVRDHIFSQQHISKVKDTIGSQLDKEKEYFDPATVRQLMAQQELDRI 3084 Query: 2335 LKAPPATTPASMPLG--------------AAPTLPRLAPVLLSGPALAQPPLGNLAPFNS 2380 KA A+ G A P L + PVLL P L P L P N+ Sbjct: 3085 KKANEVLGLAAQQQGMFDNTPLQALNLPTAYPALQGIPPVLL--PGLNSPSLPGFTPSNT 3142 Query: 2381 G-PAASSGLLGLATSVLPTTTVVQTAGPGRPL-----------------PQRPMPDQTNT 2422 + L+GL ++ +P+ + + P +P PQ+P Q Sbjct: 3143 ALTSPKPNLMGLPSTTVPSPGLPTSGLPNKPSSASLSSPTPAQATMAMGPQQPPQQQQQQ 3202 Query: 2423 STAGTTDPVPGPPTEPL-----------------GDKVSSERK-------PVAGPTSSSN 2458 P P P +P +KV + K P+ P Sbjct: 3203 QQPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKVKEKEKAHKGKGEPLPVPKKEKG 3262 Query: 2459 DA-----------------------LKNLKALKTTVP-ALLGGQFLPFPLPPAGGTAPPA 2494 +A L+ L+A T+ P ALL QFLP+ +P P Sbjct: 3263 EAPTATAATISAPLPTMEYAVDPAQLQALQAALTSDPTALLTSQFLPYFVPGFSPYYAPQ 3322 Query: 2495 VFGPQLQGAYFQQLYGMKKGLFPMNPMIPQTLIGLLPNALLQ------------------ 2536 + G LQ Y Q +YGM +GLFP +P + Q L+GL P +LLQ Sbjct: 3323 IPG-ALQSGYLQPMYGM-EGLFPYSPALSQALMGLSPGSLLQQYQQYQQSLQEAIQQQQQ 3380 Query: 2537 -----------------------PP--PQPPEPTATAPPKP--------------PELPA 2557 PP P P + A PKP P+LP Sbjct: 3381 RQLQQQQQQKVQQQQPKASQTPVPPGAPSPDKDPAKESPKPEEQKNTPREVSPLLPKLPE 3440 Query: 2558 PGEGEAGEVDELLTGSTGISTVDVTHRYLCRQCKMAFDGEAPATAHQRSFCFFGRGSGGS 2617 E E+ D L V ++ +CR+C+ F E A +H +S CFFG+ Sbjct: 3441 EPEAESKSADSLY---DPFIVPKVQYKLVCRKCQAGFSDEEAARSHLKSLCFFGQSVVNL 3497 Query: 2618 MPPPLRVPI--------------------CTYHCLACEVLLSGREALASHLRSSAHRRKA 2657 L VP +YHCLACE L G EAL+ HL S+ H+ + Sbjct: 3498 QEMVLHVPTGGGGGGSGGGGGGGGGGGGGGSYHCLACESALCGEEALSQHLESALHKHR- 3556 Query: 2658 APPQGGPPISITNAATAASAAVAFAKEEARLPHTDSNPKTTTTST 2702 +IT AA A + + LPH+ P +T ST Sbjct: 3557 ---------TITRAARNAK------EHPSLLPHSACFPDPSTAST 3586 Score = 169 bits (427), Expect = 4e-41 Identities = 179/722 (24%), Positives = 275/722 (38%), Gaps = 207/722 (28%) Query: 1264 VPEPDAQAEDVAPPPTMAEEEEGTTGELRSAEPAPADSRHPLTYRKTTNFALDKFLDPAR 1323 V E + D+ + + G+ E +EP A L +RK NF ++KFLDP+R Sbjct: 1489 VEEDKEEESDLEDKQSPTGSDSGSVQEDSGSEPKRA-----LPFRKGPNFTMEKFLDPSR 1543 Query: 1324 PYKCTV---------------------------------------------------CKE 1332 PYKCTV C Sbjct: 1544 PYKCTVCKESFTQKNILLVHYNSVSHLHKLKRALQESATGQPEPTSSPDNKPFKCNTCNV 1603 Query: 1333 SFTQKNILLVHYNSVSHLHKMKKAAIDPSAPARGEAGAPPTTTAATDKPFKCTVCR---- 1388 +++Q + L +H SV H K + A ++ ++ + G + + ++ P + Sbjct: 1604 AYSQSSTLEIHMRSVLHQTKARAAKLEAASGSSNGTGNSSSISLSSSTPSPVSTSGSNTF 1663 Query: 1389 VSYNQSSTLEIHMRSVLHQTRSR-------GTKTDSKIEGPE----------------RS 1425 + N SS ++L Q + G + I P R Sbjct: 1664 TTSNPSSAGIAPSSNLLSQVPTESVGMPPLGNPIGANIASPSEPKEANRKKLADMIASRQ 1723 Query: 1426 QEEPKEGETEGEVGTEKKGPDTSGFISGLPFLSPPPPPLDLHRFPAPLFTPPVLPPFPLV 1485 Q++ ++ + + + +++ + + + + LF P +LP FP+ Sbjct: 1724 QQQQQQQQQQQQQQQQQQAQTLAQAQAQVQAHLQQELQQQAALIQSQLFNPTLLPHFPMT 1783 Query: 1486 PESLLKLQQQQ-LLLPFYLH--DLKVGPK---------LTLAGPAPVL--SLPAATPPPP 1531 E+LL+LQQQQ LL PFY+ + ++ P+ LTL G P L L A P Sbjct: 1784 TETLLQLQQQQHLLFPFYIPSAEFQLNPEVSLPVTSGALTLTGTGPGLLEDLKAQVQVPQ 1843 Query: 1532 -------PQPPKAELA--------------------------EREWERPPMAKEGNEAG- 1557 PQ + +L+ E+E +R + EG E Sbjct: 1844 QSHQQILPQQQQNQLSIAQSHSALLQPSQHPEKKNKLVIKEKEKESQRERDSAEGGEGNT 1903 Query: 1558 -------------------------PSSPPDPLPNEAARTAAKALLENFGFELVIQYNEG 1592 PS P + ++A A KALLENFGFELVIQYNE Sbjct: 1904 GPKETLPDALKAKEKKELAPGGGSEPSMLPPRIASDARGNATKALLENFGFELVIQYNEN 1963 Query: 1593 KQAVPPPPTPPPP-EALGGGDKLACGACGKLFSNMLILKTHEEHVHRRFLPFEALSRYAA 1651 KQ V E L +KL C +CGKLFSN+LILK+H+EHVH+ + PF+ L R+A Sbjct: 1964 KQKVQKKNGKTDQGENL---EKLECDSCGKLFSNILILKSHQEHVHQNYFPFKQLERFAK 2020 Query: 1652 QFRKSYDSLY---PPLAEPPKPPDGSLDSPVPHLGP-PFLVP------EPEAGGTRAPEE 1701 Q+R YD LY P EPP PP P+P P P P P T AP + Sbjct: 2021 QYRDHYDKLYPLRPQTPEPPPPPPPPPPPPLPAAPPQPASTPAIPASAPPITSPTIAPAQ 2080 Query: 1702 RSRAGGHWPIEEE--------------ESSRGNLPP-----------------------L 1724 S + E ++ LPP L Sbjct: 2081 PSVPLTQLSMPMELPIFSPLMMQTMPLQTLPAQLPPQLGPVEPLPADLAQLYQHQLNPTL 2140 Query: 1725 VPAGRRFSRTKFTEFQTQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKA 1784 + + RT+ T+ Q + L+ +F+ + P + +++ +A GL +V+ WF+N K Sbjct: 2141 LQQQNKRPRTRITDDQLRVLRQYFDINNSPSEEQIKEMADKSGLPQKVIKHWFRNTLFKE 2200 Query: 1785 RK 1786 R+ Sbjct: 2201 RQ 2202 Score = 169 bits (427), Expect = 4e-41 Identities = 111/264 (42%), Positives = 150/264 (56%), Gaps = 40/264 (15%) Query: 1829 DQTLEEEEEEAERGEEEEEVEEEEVEEEQGL----------EPPAG---PEGPLPEP-PD 1874 +QT E++ + +++E+ E++ +Q L +PP P+ PLP+ P Sbjct: 2441 NQTQEKQGQPKPELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPPPQAPPPQCPLPQSSPS 2500 Query: 1875 GEELSQAEATKAGGKEPEEKATPSPSPA-HTCDQCAISFSSQDLLTSHRRLHFLPSLQPS 1933 +LS P++ A P + CDQC ++F S + H++LHFL + Sbjct: 2501 PSQLSHLPLKPLHTSTPQQLANLPPQLIPYQCDQCKLAFPSFEHWQEHQQLHFLSAQNQF 2560 Query: 1934 APPQLLD----LPLLVFGERNPLVAA-------------TSPMPGPP------LKRKHED 1970 PQ LD +P ++F NPL+A+ ++ P P LKRK E+ Sbjct: 2561 IHPQFLDRSLDMPFMLFDPSNPLLASQLLSGAIPQIPASSATSPSTPTSTMNTLKRKLEE 2620 Query: 1971 -GSLSPTGSEAGGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVG 2029 S SP +++G GGE EP RDKRLRTTI PEQLEILY+ Y+ DSNPTRKMLD I+ EVG Sbjct: 2621 KASASPGENDSGTGGE-EPQRDKRLRTTITPEQLEILYQKYLLDSNPTRKMLDHIAHEVG 2679 Query: 2030 LKKRVVQVWFQNTRARERKGQFRS 2053 LKKRVVQVWFQNTRARERKGQFR+ Sbjct: 2680 LKKRVVQVWFQNTRARERKGQFRA 2703 Score = 114 bits (284), Expect = 2e-24 Identities = 129/504 (25%), Positives = 189/504 (37%), Gaps = 100/504 (19%) Query: 1528 PPPPPQPPKAELAEREWERPPMAKEGNEAGPSSPPDPLPNEAARTAAKALLE-NFGFELV 1586 PPPPP PP A PP S+PP P A + L + + EL Sbjct: 2042 PPPPPPPPPLPAA------PPQPASTPAIPASAPPITSPTIAPAQPSVPLTQLSMPMELP 2095 Query: 1587 IQYNEGKQAVPPPPTPPP-PEALGGGDKLACGACGKLFSNML---ILKTHEEHVHRRFLP 1642 I Q +P P P LG + L +L+ + L +L+ + R Sbjct: 2096 IFSPLMMQTMPLQTLPAQLPPQLGPVEPLPADLA-QLYQHQLNPTLLQQQNKRPRTRITD 2154 Query: 1643 --FEALSRYAAQFRKSYDSLYPPLAEPPKPPDGSL----------------DSPVPHLGP 1684 L +Y + +A+ P + DSP P Sbjct: 2155 DQLRVLRQYFDINNSPSEEQIKEMADKSGLPQKVIKHWFRNTLFKERQRNKDSPYNFSNP 2214 Query: 1685 PFLVPEPEAGGTRAPEERSRAGGHWPIEEEESSRGNLPPLVPAGRRFSRTKFTEFQTQAL 1744 P E +R P +W +R SRT+FT++Q + L Sbjct: 2215 PITSLEELKIDSRPPSPEPPKQEYW-----------------GSKRSSRTRFTDYQLRVL 2257 Query: 1745 QSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARKNACEGGSMPTGGGTGGAS 1804 Q FF+ +AYPKD E E+L++LL L +RV+VVWFQNARQKARKN G G + Sbjct: 2258 QDFFDANAYPKDDEFEQLSNLLNLPTRVIVVWFQNARQKARKNYENQGEGKDGERRELTN 2317 Query: 1805 G-----------CRRCHATFSCVFELVRHLKK-CYDDQTLEEEEEEAERGEEEEEVEEEE 1852 C++C F +F+L++H KK CY D E+EE + + E+ ++ E Sbjct: 2318 DRYIRTSNLNYQCKKCSLVFQRIFDLIKHQKKLCYKD----EDEEGQDDSQNEDSMDAME 2373 Query: 1853 VEEEQGLE-----PPAGPEGPLPE------------PPDGEELSQAEA-TKAGGKEPEEK 1894 + P P P + EEL+ + T+AG ++P+ Sbjct: 2374 ILTPTSSSCSTPMPSQAYSAPAPSANNTASSAFLQLTAEAEELATFNSKTEAGDEKPKLA 2433 Query: 1895 ATPSPSPAHTCDQCA--------------ISFSSQDLLTSHRRLHFLPSLQPSAPPQLLD 1940 PS P T ++ + + Q L L LP P APP Sbjct: 2434 EAPSAQPNQTQEKQGQPKPELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPPPQAPPPQCP 2493 Query: 1941 LPLLVFGERNPLVAATSPMPGPPL 1964 LP + +P + S +P PL Sbjct: 2494 LP-----QSSPSPSQLSHLPLKPL 2512 Score = 76.6 bits (187), Expect = 3e-13 Identities = 138/601 (22%), Positives = 205/601 (34%), Gaps = 139/601 (23%) Query: 1520 VLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPSSPPDPLPNEAARTAAKALLE 1579 ++SLP+ P PPPQ P PP + S LP + T+ L Sbjct: 2474 LVSLPSL-PQPPPQAP-----------PPQCPLPQSSPSPSQLSHLPLKPLHTSTPQQLA 2521 Query: 1580 NFGFELVIQYNEGKQAVPPPPTPPPPEALGGGDKLACGACGKLFSNMLILKTHEE----H 1635 N +PP P C C F + + H++ Sbjct: 2522 N---------------LPPQLIP-----------YQCDQCKLAFPSFEHWQEHQQLHFLS 2555 Query: 1636 VHRRFLPFEALSRYAAQFRKSYDSLYPPLAEP------PKPPDGSLDSP-VPHLGPPFLV 1688 +F+ + L R +D P LA P+ P S SP P L Sbjct: 2556 AQNQFIHPQFLDRSLDMPFMLFDPSNPLLASQLLSGAIPQIPASSATSPSTPTSTMNTLK 2615 Query: 1689 PEPEAGGTRAPEER-SRAGGHWPIEEEESSRGNLPPLVPAGRRFSRTKFTEFQTQALQSF 1747 + E + +P E S GG P ++ RT T Q + L Sbjct: 2616 RKLEEKASASPGENDSGTGGEEPQRDKRL----------------RTTITPEQLEILYQK 2659 Query: 1748 FETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARKNACEGGSMPTGGGTGGASGCR 1807 + + P ++ +A +GL RVV VWFQN R + RK G G C Sbjct: 2660 YLLDSNPTRKMLDHIAHEVGLKKRVVQVWFQNTRARERK-----GQFRAVGPAQAHRRCP 2714 Query: 1808 RCHATFSCVFELVRHLKKCYDDQTLEEEEEEAERGEEEEEVEEEEVEEEQGLE------- 1860 C A F L H++ EA+R + ++ + GL+ Sbjct: 2715 FCRALFKAKTALEAHIR--------SRHWHEAKRAGYNLTLSAMLLDCDGGLQMKGDIFD 2766 Query: 1861 -------PPAGPEG---PLPEPPDGEELS-----QAEATKAGGKEPEEKATPSPSPAH-- 1903 PP+ +G PL ELS + K G E E +PS S + Sbjct: 2767 GTSFSHLPPSSSDGQGVPLSPVSKTMELSPRTLLSPSSIKVEGIEDFE--SPSMSSVNLN 2824 Query: 1904 ------TCDQC-AISFSSQDLLT-------SHRRLHFLPSLQPSAPPQ--LLDLPLLVFG 1947 D C +++ + D T + + S+ P L ++ Sbjct: 2825 FDQTKLDNDDCSSVNTAITDTTTGDEGNADNDSATGIATETKSSSAPNEGLTKAAMMAMS 2884 Query: 1948 ERNPLVAATSPMPGPPLKRKHEDG----------------SLSP--TGSEAGGGGEGEPP 1989 E +++ P P K D S SP +GS G G+ P Sbjct: 2885 EYEDRLSSGLVSPAPSFYSKEYDNEGTVDYSETSSLADPCSPSPGASGSAGKSGDSGDRP 2944 Query: 1990 RDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQNTRARERKG 2049 KR RT + QL++L + PT + + ++GL KRVVQVWFQN RA+E+K Sbjct: 2945 GQKRFRTQMTNLQLKVLKSCFNDYRTPTMLECEVLGNDIGLPKRVVQVWFQNARAKEKKS 3004 Query: 2050 Q 2050 + Sbjct: 3005 K 3005 Score = 71.2 bits (173), Expect = 1e-11 Identities = 46/159 (28%), Positives = 72/159 (45%), Gaps = 12/159 (7%) Query: 2150 ASPESEACSLSAGDLSDSSASSLAEPESPGAGGTSGGPGGGTGVPDGMGQRRYRTQMSSL 2209 A P+ A S ++ S+ ++L A + G GTG + +R RT ++ Sbjct: 2592 AIPQIPASSATSPSTPTSTMNTLKRKLEEKASASPGENDSGTGGEEPQRDKRLRTTITPE 2651 Query: 2210 QLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAKLQGTAAGSTGG 2269 QL+I+ Y PT + + + E+GL KRV+QVWFQN RA+E+K + + Sbjct: 2652 QLEILYQKYLLDSNPTRKMLDHIAHEVGLKKRVVQVWFQNTRARERKGQFRAVGP----- 2706 Query: 2270 SSEGLLAAQRTDCPYCDVKYDFYVSCRGHLFSRQ-HLAK 2307 A CP+C + + H+ SR H AK Sbjct: 2707 ------AQAHRRCPFCRALFKAKTALEAHIRSRHWHEAK 2739 Score = 58.2 bits (139), Expect = 1e-07 Identities = 104/406 (25%), Positives = 147/406 (36%), Gaps = 55/406 (13%) Query: 2199 QRRYRTQMSSLQLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAK 2258 +R RT+ + QL++++ ++A P E E L + LP RVI VWFQNAR K +K Sbjct: 2242 KRSSRTRFTDYQLRVLQDFFDANAYPKDDEFEQLSNLLNLPTRVIVVWFQNARQKARK-N 2300 Query: 2259 LQGTAAGSTGGSSEGLLAAQR--------TDCPYCDVKYDFYVSCRGHLFSRQHLAKLKE 2310 + G G E L R C C + + H ++ L E Sbjct: 2301 YENQGEGKDGERRE--LTNDRYIRTSNLNYQCKKCSLVFQRIFDLIKH---QKKLCYKDE 2355 Query: 2311 AVRAQLKSESKCYDLAPAPE----APPALKAPPATTPASMPLGAAPTLPRLAPVLLSGPA 2366 Q S+++ D A E + P + S P +A A + L+ A Sbjct: 2356 DEEGQDDSQNE--DSMDAMEILTPTSSSCSTPMPSQAYSAPAPSANNTASSAFLQLTAEA 2413 Query: 2367 LAQPPLGNLAPFNSGPAA--SSGLLGLATSVLPTTTVVQTAGPGRPLPQRPMPDQ-TNTS 2423 LA FNS A L A S P T + P L Q+ P+Q TNT Sbjct: 2414 ------EELATFNSKTEAGDEKPKLAEAPSAQPNQTQEKQGQPKPELQQQEQPEQKTNTP 2467 Query: 2424 TAGTTDPV--PGPPTEPLGDKVSSERKPVAGPTSSSNDALKNLKALKTTVP---ALLGGQ 2478 V P P P P + P+ S L LK L T+ P A L Q Sbjct: 2468 QQKLPQLVSLPSLPQPPPQAPPPQCPLPQSSPSPSQLSHLP-LKPLHTSTPQQLANLPPQ 2526 Query: 2479 FLPFPLPPAGGTAPPAVFGPQLQGAYF-------------QQLYGMKKGLF-PMNPMI-P 2523 +P+ P + Q +F + M LF P NP++ Sbjct: 2527 LIPYQCDQCKLAFPSFEHWQEHQQLHFLSAQNQFIHPQFLDRSLDMPFMLFDPSNPLLAS 2586 Query: 2524 QTLIGLLPNALLQPPPQPPEPTATAPPKPPEL-----PAPGEGEAG 2564 Q L G +P P PT+T +L +PGE ++G Sbjct: 2587 QLLSGAIPQIPASSATSPSTPTSTMNTLKRKLEEKASASPGENDSG 2632 Score = 53.5 bits (127), Expect = 3e-06 Identities = 52/210 (24%), Positives = 97/210 (46%), Gaps = 35/210 (16%) Query: 1862 PAGPEGPLPEPPDGEELSQAEATKAGGKEPEEKATPSPSPAHTCDQCAISFSSQDLLTSH 1921 P PE P P PP P A P P PA T AI S+ + + Sbjct: 2034 PQTPEPPPPPPPP--------------PPPPLPAAP-PQPASTP---AIPASAPPITSPT 2075 Query: 1922 RRLHFLPSLQPSAPPQLLDLP--LLVFGERNPLVAATSPMPGPPLKRKHEDGSLSPTGSE 1979 + QPS P L +P L +F +PL+ T P+ P + + G + P ++ Sbjct: 2076 -----IAPAQPSVPLTQLSMPMELPIF---SPLMMQTMPLQTLPAQLPPQLGPVEPLPAD 2127 Query: 1980 AGGGGEGE------PPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKR 2033 + + ++KR RT I +QL +L +++ +++P+ + + ++++ GL ++ Sbjct: 2128 LAQLYQHQLNPTLLQQQNKRPRTRITDDQLRVLRQYFDINNSPSEEQIKEMADKSGLPQK 2187 Query: 2034 VVQVWFQNTRARERKGQFRSTPGGVPSPAV 2063 V++ WF+NT +ER+ + + +P +P + Sbjct: 2188 VIKHWFRNTLFKERQ-RNKDSPYNFSNPPI 2216 Score = 50.4 bits (119), Expect = 2e-05 Identities = 40/171 (23%), Positives = 72/171 (42%), Gaps = 30/171 (17%) Query: 2111 PQPFLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESEACSLSAGDLSDSSAS 2170 P+P PP P P PPLP PP P S P P + + A + + L+ S Sbjct: 2037 PEPPPPP-----PPPPPPPLPAAPPQPASTPAIPASAPPITSPTIAPAQPSVPLTQLSMP 2091 Query: 2171 SLAEPESPGAGGTSGGPGGGTGVPDGMG-------------------------QRRYRTQ 2205 SP T +P +G +R RT+ Sbjct: 2092 MELPIFSPLMMQTMPLQTLPAQLPPQLGPVEPLPADLAQLYQHQLNPTLLQQQNKRPRTR 2151 Query: 2206 MSSLQLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKK 2256 ++ QL++++ ++ +P+ ++ + + ++ GLP++VI+ WF+N KE++ Sbjct: 2152 ITDDQLRVLRQYFDINNSPSEEQIKEMADKSGLPQKVIKHWFRNTLFKERQ 2202 Score = 49.3 bits (116), Expect = 5e-05 Identities = 31/105 (29%), Positives = 41/105 (39%), Gaps = 21/105 (20%) Query: 1323 RPYKCTVCKESFTQKNILLVHYNSVSHLHKMKK---------------------AAIDPS 1361 +P++C VC S T K L +H S HL+ M+ AA + Sbjct: 724 KPFRCEVCNYSTTTKGNLSIHMQSDKHLNNMQNLQNGGGEQVFSHTAGAAAAAVAAAAAA 783 Query: 1362 APARGEAGAPPTTTAATDKPFKCTVCRVSYNQSSTLEIHMRSVLH 1406 A GAP T T ++C VC N + L IHM S H Sbjct: 784 ANISSSCGAPSPTKPKTKPTWRCEVCDYETNVARNLRIHMTSEKH 828 Score = 47.0 bits (110), Expect = 3e-04 Identities = 32/89 (35%), Positives = 42/89 (47%), Gaps = 12/89 (13%) Query: 506 KPYRCDVCNYSTTTKGNLSIHMQSDKHLANL-QGFQAGPGGQGSPPEASLPPSAGDKEPK 564 +PY+C VC S T K L +H S HL L + Q GQ PE P S+ D +P Sbjct: 1543 RPYKCTVCKESFTQKNILLVHYNSVSHLHKLKRALQESATGQ---PE---PTSSPDNKP- 1595 Query: 565 TKSSWQCKVCSYETNISRNLRIHMTSEKH 593 ++C C+ + S L IHM S H Sbjct: 1596 ----FKCNTCNVAYSQSSTLEIHMRSVLH 1620 Score = 45.1 bits (105), Expect = 0.001 Identities = 72/308 (23%), Positives = 113/308 (36%), Gaps = 60/308 (19%) Query: 23 LPSDTFSSSTPSDPVTKDPPAASSTSENMRSSEPGGQLLESGCGLVPPKEIGEPQEGPDC 82 L T S+ PS+P +K+ + S + S + +E C P P Sbjct: 61 LAESTASAGPPSEPASKEV-TCNECSASFASLQT---YMEHHCPSARPP--------PPL 108 Query: 83 GHFPPNDPGVEKDKEQEEEEEGLPPMDLSNHLFFTAGGEAYLVAKLSL---------PGG 133 +D G E D+E + E +L+ + + G AY+V LS G Sbjct: 109 REESASDTGEEGDEESDVE-------NLAGEIVYQPDGSAYIVESLSQLTQGGGACGSGS 161 Query: 134 SELLLPKGF----PWGEAGIKEEPSLPFLAYPPPSHLTALHIQHGFD-----PIQGFSSS 184 LP F P G G + +PS YP + HI F P Q F ++ Sbjct: 162 GSGPLPSLFLNSLP-GAGGKQGDPSCAAPVYP--QIINTFHIASSFGKWFEGPDQAFPNT 218 Query: 185 DQILSHDTSAPSPAACEERHGAFWSYQLAPNPPGDPKDGPMGNSGGNHVAV--------- 235 + S + RH + Y N G K + N+V + Sbjct: 219 SALAGLSPVLHSFRVFDVRHKSNKDYL---NSDGSAKSSCVSKDVPNNVDLSKFDGFVLY 275 Query: 236 -----FWLCLLCRLGFSKPQAFMDH-TQSHGVKLTPAQYQGLSGS--PAVLQEGDEGCKA 287 +C LC+L F ++F+ H H + L+ + + LS A++Q + + Sbjct: 276 GKRKPILMCFLCKLSFGYVRSFVTHAVHDHRMTLSEDERKILSNKNISAIIQGIGKDKEP 335 Query: 288 LISFLEPK 295 L+SFLEPK Sbjct: 336 LVSFLEPK 343 Score = 45.1 bits (105), Expect = 0.001 Identities = 81/389 (20%), Positives = 127/389 (32%), Gaps = 104/389 (26%) Query: 1845 EEEVEEEEVEEEQGLEPPAGPEGPLPEPP----------DGEELSQAEATKAGGKE--PE 1892 +++ ++++ + +Q PPA P P+ P D E++ + E G E P Sbjct: 3197 QQQQQQQQPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKVKEKEKAHKGKGEPLPV 3256 Query: 1893 EKATPSPSPAHTCDQCAISFSSQDLLTSHRRLHFLPSLQPSAPPQLLDLPLLVFGERNPL 1952 K +P T + + + +L L + S P LL L + Sbjct: 3257 PKKEKGEAPTATAATISAPLPTMEYAVDPAQLQALQAALTSDPTALLTSQFLPY-----F 3311 Query: 1953 VAATSPMPGPPLKRKHEDGSLSPTGSEAGGGGEGEPPRDKRLRTTIL---PEQLEILYRW 2009 V SP P + + G L P G EG P L ++ P L Y+ Sbjct: 3312 VPGFSPYYAPQIPGALQSGYLQPM-----YGMEGLFPYSPALSQALMGLSPGSLLQQYQQ 3366 Query: 2010 YMQDSNPTRKMLDCISEEVGLKKRVVQVWFQNTRARERKGQFRSTPGGVPSPAVKPPATA 2069 Y Q + + I ++ ++++ Q Q + ++ K P G PSP Sbjct: 3367 YQQ------SLQEAIQQQ--QQRQLQQQQQQKVQQQQPKASQTPVPPGAPSP-------- 3410 Query: 2070 TPASLPKFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQPFLPPGKEATTPTP-EP 2128 D +E+PK P ++ TP P Sbjct: 3411 ---------------DKDPAKESPK----------------------PEEQKNTPREVSP 3433 Query: 2129 PLPLLPPPPPSEEEG------PEEPPKASPESEACSLSAGDLSDSSASS----------- 2171 LP LP P +E + P PK + AG + +A S Sbjct: 3434 LLPKLPEEPEAESKSADSLYDPFIVPKVQYKLVCRKCQAGFSDEEAARSHLKSLCFFGQS 3493 Query: 2172 --------LAEPESPGAGGTSGGPGGGTG 2192 L P G GG+ GG GGG G Sbjct: 3494 VVNLQEMVLHVPTGGGGGGSGGGGGGGGG 3522 Score = 40.4 bits (93), Expect = 0.024 Identities = 25/62 (40%), Positives = 33/62 (53%), Gaps = 4/62 (6%) Query: 1797 GGGTGGASGCRRCHATFSCVFELVRHLKKCYDDQTLEEEEEEAERGEEEEEVEEEEVEEE 1856 G +G A G ++ C E V +++ EEEEEE EEEEE EEEE EE+ Sbjct: 433 GKDSGAAEGEKQEVGDGDCFSEKVEPA----EEEAEEEEEEEEAEEEEEEEEEEEEEEED 488 Query: 1857 QG 1858 +G Sbjct: 489 EG 490 Score = 40.4 bits (93), Expect = 0.024 Identities = 34/115 (29%), Positives = 42/115 (36%), Gaps = 26/115 (22%) Query: 602 QGLPLGLPPGLMGPGPP--PPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLR----PD 655 QG+P L PGL P P P TSP P +G P T + PGL P+ Sbjct: 3119 QGIPPVLLPGLNSPSLPGFTPSNTALTSPK-------PNLMGLPSTTVPSPGLPTSGLPN 3171 Query: 656 KPLEAQLLLNGFHHVGAPARKFPTSAPGSLSPDAHLPPSQLLGSSSDSLPTSPPP 710 KP A L PT A +++ PP Q + PPP Sbjct: 3172 KPSSASL-------------SSPTPAQATMAMGPQQPPQQQQQQQQPQVQQPPPP 3213 Score = 40.0 bits (92), Expect = 0.031 Identities = 25/53 (47%), Positives = 31/53 (58%), Gaps = 3/53 (5%) Query: 1826 CYDDQTLEEEEEEAERGEEEEEVEEEE--VEEEQGLEPPAGPEGPLPEPPDGE 1876 C+ ++ +E EEEAE EEEEE EEEE EEE+ E G +G P D E Sbjct: 451 CFSEK-VEPAEEEAEEEEEEEEAEEEEEEEEEEEEEEEDEGCKGLFPSELDEE 502 Score = 38.5 bits (88), Expect = 0.091 Identities = 37/167 (22%), Positives = 56/167 (33%), Gaps = 14/167 (8%) Query: 1253 PGQPPSPAPSPVPEPDAQAEDVAPPPTMAEEEEGTTGELRSAEPAPADSRHPLTYRKTTN 1312 P +P P P PD +P P EE++ T E+ P + P K+ + Sbjct: 3396 PKASQTPVPPGAPSPDKDPAKESPKP---EEQKNTPREVSPLLPKLPEE--PEAESKSAD 3450 Query: 1313 FALDKFLDPARPYK--CTVCKESFTQKNILLVHYNS-------VSHLHKMKKAAIDPSAP 1363 D F+ P YK C C+ F+ + H S V +L +M Sbjct: 3451 SLYDPFIVPKVQYKLVCRKCQAGFSDEEAARSHLKSLCFFGQSVVNLQEMVLHVPTGGGG 3510 Query: 1364 ARGEAGAPPTTTAATDKPFKCTVCRVSYNQSSTLEIHMRSVLHQTRS 1410 G + C C + L H+ S LH+ R+ Sbjct: 3511 GGSGGGGGGGGGGGGGGSYHCLACESALCGEEALSQHLESALHKHRT 3557 Score = 37.4 bits (85), Expect = 0.20 Identities = 23/97 (23%), Positives = 41/97 (42%), Gaps = 12/97 (12%) Query: 758 HRCKLCCYGTQLKANFQLHLKTDKHAQKYQLAAHLREGGGAMGTPSPASLGDGAPYGSVS 817 ++C +C K +H + H K + A L+E A G P P S D P+ Sbjct: 1545 YKCTVCKESFTQKNILLVHYNSVSHLHKLKRA--LQES--ATGQPEPTSSPDNKPF---- 1596 Query: 818 PLHLRCNICDFESNSKEKMQLHARGAAHEENSQIYKV 854 +CN C+ + +++H R H+ ++ K+ Sbjct: 1597 ----KCNTCNVAYSQSSTLEIHMRSVLHQTKARAAKL 1629 Score = 37.0 bits (84), Expect = 0.26 Identities = 21/68 (30%), Positives = 33/68 (48%), Gaps = 6/68 (8%) Query: 1987 EPPRD------KRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQ 2040 EPP+ + RT QL +L ++ ++ P + +S + L RV+ VWFQ Sbjct: 2232 EPPKQEYWGSKRSSRTRFTDYQLRVLQDFFDANAYPKDDEFEQLSNLLNLPTRVIVVWFQ 2291 Query: 2041 NTRARERK 2048 N R + RK Sbjct: 2292 NARQKARK 2299 Score = 35.0 bits (79), Expect = 1.0 Identities = 123/613 (20%), Positives = 197/613 (32%), Gaps = 136/613 (22%) Query: 1877 ELSQAEATKAGGKEPEEKATPSPSPAHTCDQCAISFSSQDLLTSHRR--LHFLP------ 1928 +L +A A G +PE ++P P C+ C +++S L H R LH Sbjct: 1572 KLKRALQESATG-QPEPTSSPDNKP-FKCNTCNVAYSQSSTLEIHMRSVLHQTKARAAKL 1629 Query: 1929 ----------------SLQPSAPPQLLDLPLLVFGERNPLVAATSPMPGPPLKRKHEDGS 1972 SL S P + F NP A +P + E Sbjct: 1630 EAASGSSNGTGNSSSISLSSSTPSPVSTSGSNTFTTSNPSSAGIAPSSNLLSQVPTESVG 1689 Query: 1973 LSPTGSEAGGG----GEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEV 2028 + P G+ G E + K+L I Q + + Q ++ +++ Sbjct: 1690 MPPLGNPIGANIASPSEPKEANRKKLADMIASRQQQQQQQQQQQQQQQQQQQAQTLAQAQ 1749 Query: 2029 GLKKRVVQVWFQNTRARERKGQFRSTPGGVPSPAVKPPATATPASLPKFNLLLGKVDDGT 2088 + +Q Q A + F P LP F + T Sbjct: 1750 AQVQAHLQQELQQQAALIQSQLFN------------------PTLLPHFPMTTE-----T 1786 Query: 2089 GREAPKREAPAFPY--PTATLASGPQPFLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEE 2146 + +++ FP+ P+A P+ LP A T T P LL + + Sbjct: 1787 LLQLQQQQHLLFPFYIPSAEFQLNPEVSLPVTSGALTLTGTGP-GLLEDLKAQVQVPQQS 1845 Query: 2147 PPKASPESEACSLSAGDLSDSSASSLAEP---------------------ESPGAGGTSG 2185 + P+ + LS S S+L +P E A G G Sbjct: 1846 HQQILPQQQQNQLSIAQ----SHSALLQPSQHPEKKNKLVIKEKEKESQRERDSAEGGEG 1901 Query: 2186 GPGGGTGVPDGMGQRRYR-------TQMSSLQLKIMKACYEAYRTPTMQECEVLGEEIGL 2238 G +PD + + + ++ S L +I +A T E G E+ Sbjct: 1902 NTGPKETLPDALKAKEKKELAPGGGSEPSMLPPRIAS---DARGNATKALLENFGFEL-- 1956 Query: 2239 PKRVIQVWFQNARAKEKKAKLQGTAAGSTGGSSEGLLAAQRTDCPYCDVKYDFYVSCRGH 2298 VIQ E K K+Q + G + ++ +C C + + + H Sbjct: 1957 ---VIQY-------NENKQKVQKKNGKTDQGEN-----LEKLECDSCGKLFSNILILKSH 2001 Query: 2299 LFSRQHL-------AKLKEAVRAQLKSESKCYDLAPAPEAPPALKAPPATTPASMPLGAA 2351 ++H+ +L+ + K Y L P PP PP P PL AA Sbjct: 2002 ---QEHVHQNYFPFKQLERFAKQYRDHYDKLYPLRPQTPEPP----PPPPPPPPPPLPAA 2054 Query: 2352 PTLPRLAPVL-LSGPALAQPPLGNLAPFNSGPAASSGL---LGLATSVLPTTTVVQT--- 2404 P P P + S P + P + P S P + L + + ++ T +QT Sbjct: 2055 PPQPASTPAIPASAPPITSPTIAPAQP--SVPLTQLSMPMELPIFSPLMMQTMPLQTLPA 2112 Query: 2405 -----AGPGRPLP 2412 GP PLP Sbjct: 2113 QLPPQLGPVEPLP 2125 Score = 35.0 bits (79), Expect = 1.0 Identities = 17/38 (44%), Positives = 19/38 (50%), Gaps = 5/38 (13%) Query: 2520 PMIPQTLIGLLPNALLQPPPQPPEPTATAPPKPPELPA 2557 P+ PQT P PPP PP P APP+P PA Sbjct: 2031 PLRPQT-----PEPPPPPPPPPPPPLPAAPPQPASTPA 2063 Score = 34.7 bits (78), Expect = 1.3 Identities = 32/103 (31%), Positives = 45/103 (43%), Gaps = 9/103 (8%) Query: 1843 EEEEEVEEEEVEEEQGLE---PPAGPEGPLPEPPDGEELSQAEATKAGGKEPEEKATPSP 1899 E+ + EE+ EEE LE P G + + G E +A + G EK P Sbjct: 1483 EDHTIIVEEDKEEESDLEDKQSPTGSDSGSVQEDSGSEPKRALPFRKGPNFTMEKFL-DP 1541 Query: 1900 SPAHTCDQCAISFSSQDLLTSH----RRLHFLP-SLQPSAPPQ 1937 S + C C SF+ +++L H LH L +LQ SA Q Sbjct: 1542 SRPYKCTVCKESFTQKNILLVHYNSVSHLHKLKRALQESATGQ 1584 Score = 33.9 bits (76), Expect = 2.2 Identities = 52/233 (22%), Positives = 86/233 (36%), Gaps = 47/233 (20%) Query: 1383 KCTVCRVSYNQSSTLEIHMRSVLHQTRSRGTKTDSKIEGPERSQEEP---KEGETEGEVG 1439 +CT+C + Y+ ++ H+ S H ++ + T S+++ E+ +P ++ + E+ Sbjct: 3025 ECTLCGIKYSARLSVRDHIFSQQHISKVKDT-IGSQLD-KEKEYFDPATVRQLMAQQELD 3082 Query: 1440 TEKKGPDTSGFISGLP--FLSPPPPPLDLHR-FPAPLFTPPVLPPFPLVPESLLKLQQQQ 1496 KK + G + F + P L+L +PA PPVL P P Sbjct: 3083 RIKKANEVLGLAAQQQGMFDNTPLQALNLPTAYPALQGIPPVLLPGLNSPS--------- 3133 Query: 1497 LLLPFYLHDLKVGPKLTLAGPAP-VLSLPAATPPPPPQPPKA---ELAEREWERPPMAKE 1552 LP + L P P ++ LP+ T P P P + + P A+ Sbjct: 3134 --LPGFTPS-----NTALTSPKPNLMGLPSTTVPSPGLPTSGLPNKPSSASLSSPTPAQA 3186 Query: 1553 GNEAGPSSPPDPLPNEAARTAAKALLENFGFELVIQYNEGKQAVPPPPTPPPP 1605 GP PP + Q + +Q PPP PPP Sbjct: 3187 TMAMGPQQPPQQQQQQ-------------------QQPQVQQPPPPPAAQPPP 3220 Score = 33.5 bits (75), Expect = 2.9 Identities = 26/92 (28%), Positives = 34/92 (36%), Gaps = 13/92 (14%) Query: 609 PPGLMGPGPPPP-------PGATPTSPPELFQYFGPQ-ALGQPQTPLAGPGLRPDKPLEA 660 PP P PPPP P +TP P P A QP PL + + P+ + Sbjct: 2039 PPPPPPPPPPPPLPAAPPQPASTPAIPASAPPITSPTIAPAQPSVPLTQLSMPMELPIFS 2098 Query: 661 QLLLNGFHHVGAPARKFPTSAPGSLSPDAHLP 692 L++ P + P P L P LP Sbjct: 2099 PLMMQTM-----PLQTLPAQLPPQLGPVEPLP 2125 Score = 32.7 bits (73), Expect = 5.0 Identities = 53/242 (21%), Positives = 79/242 (32%), Gaps = 38/242 (15%) Query: 815 SVSPLHLRCNICDFESNSKEKMQLHARGAAHEENSQIYKVRLGAELGLYHCLLCAWETPS 874 SV P+ LRC +C N+K +QLH + K L+ TP Sbjct: 1247 SVQPM-LRCPLCQDMLNNKIHLQLHLTHLHSVAPDCVEK------------LIMTVTTPE 1293 Query: 875 RLAVLQHLRTPAHRDAQAQRRLQLLQNGPTTEEGLAALQSILSFSHGQLRTPAEVVPAEA 934 + A D L+ P T E L ++IL + + ++ Sbjct: 1294 MVMPSSMFLPAAVPDRDGNSNLEEAGKQPETSEDLG--KNILPSASTE----------QS 1341 Query: 935 GNSQPGTIDPEGTGEEPARGCQRLHLKKKKKKKKEWGRASAASKGLCDGGSHPSLTLRPL 994 G+ +P DP E+ C KK + S L + L Sbjct: 1342 GDLKPSPADPGSVREDSGFICW----------KKGCNQVFKTSAALQTHFNEVHAKRPQL 1391 Query: 995 PICSLQVYC--CPYCSFLSPESSQVRAHTLSQHAVQPKYRCPLCQEQLVGRPALHFHLSH 1052 P+ VY C CS +++ H+ H ++ C LCQ AL HL Sbjct: 1392 PVSDRHVYKYRCNQCSLAFKTIEKLQLHS-QYHVIRAATMCCLCQRSFRTFQALKKHLET 1450 Query: 1053 LH 1054 H Sbjct: 1451 SH 1452 Score = 32.7 bits (73), Expect = 5.0 Identities = 15/39 (38%), Positives = 18/39 (46%) Query: 1227 TPEASPDPLPEPPLASVEVPDKPSGSPGQPPSPAPSPVP 1265 TPE P P P PP P +P+ +P P S P P Sbjct: 2036 TPEPPPPPPPPPPPPLPAAPPQPASTPAIPASAPPITSP 2074 Score = 32.3 bits (72), Expect = 6.5 Identities = 25/76 (32%), Positives = 34/76 (44%), Gaps = 7/76 (9%) Query: 2533 ALLQPPPQPPEPTATAPPKPPELPAPGEGEAGEVDELLTGSTGISTVDVTHR---YLCRQ 2589 +L QPPPQ P P P P P+P + + L T ST ++ + Y C Q Sbjct: 2479 SLPQPPPQAPPPQC---PLPQSSPSPSQLSHLPLKPLHT-STPQQLANLPPQLIPYQCDQ 2534 Query: 2590 CKMAFDGEAPATAHQR 2605 CK+AF HQ+ Sbjct: 2535 CKLAFPSFEHWQEHQQ 2550 Score = 32.0 bits (71), Expect = 8.5 Identities = 32/130 (24%), Positives = 48/130 (36%), Gaps = 9/130 (6%) Query: 2579 VDVTHRYLCRQCKMAFDGEAPATAHQRSFCFFGR------GSGGSMPPPLRVPICT-YHC 2631 +D + Y C CK +F + H S + S P P P + C Sbjct: 1539 LDPSRPYKCTVCKESFTQKNILLVHYNSVSHLHKLKRALQESATGQPEPTSSPDNKPFKC 1598 Query: 2632 LACEVLLSGREALASHLRSSAHRRKAAPPQGGPPISITNAATAASAAVAFAKEEARLPHT 2691 C V S L H+RS H+ KA + +N T S++++ + P + Sbjct: 1599 NTCNVAYSQSSTLEIHMRSVLHQTKARAAKLEAASGSSN-GTGNSSSISLSSSTPS-PVS 1656 Query: 2692 DSNPKTTTTS 2701 S T TTS Sbjct: 1657 TSGSNTFTTS 1666 Score = 32.0 bits (71), Expect = 8.5 Identities = 45/141 (31%), Positives = 60/141 (42%), Gaps = 22/141 (15%) Query: 2053 STPGGVPSPAVKPPA-TATPASLPKFNLLLGKVDD--------GTGREAPK-REAP-AFP 2101 STP +PS A PA +A + F L + ++ G E PK EAP A P Sbjct: 2383 STP--MPSQAYSAPAPSANNTASSAFLQLTAEAEELATFNSKTEAGDEKPKLAEAPSAQP 2440 Query: 2102 YPTATLASGPQPFLPPGK--EATTPTPEPPLPLLP-----PPPPSEEEGPEEP-PKASPE 2153 T P+P L + E T TP+ LP L P PP + P+ P P++SP Sbjct: 2441 NQTQEKQGQPKPELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPPPQAPPPQCPLPQSSPS 2500 Query: 2154 -SEACSLSAGDLSDSSASSLA 2173 S+ L L S+ LA Sbjct: 2501 PSQLSHLPLKPLHTSTPQQLA 2521 >gi|126090663 zinc finger homeodomain 4 [Homo sapiens] Length = 3571 Score = 500 bits (1288), Expect = e-141 Identities = 303/779 (38%), Positives = 403/779 (51%), Gaps = 98/779 (12%) Query: 360 AKESPVAAGEAGPDWFPEGQEEDGGLCPPLNQSSPTSKEGGTLPAPVGSPEDPSDPPQPY 419 A S +A A P G E+ SS T + G P+ G+P P P Sbjct: 562 ASASKDSATAAHPSEIARGDED----------SSATPHQHGFTPSTPGTP-GPGGDGSPG 610 Query: 420 RLADDYTPAPAAFQGLSLSSHMSLLHSRNSCKTLKCPKCNWHYKYQQTLDVHMREKHPES 479 + SL HM+++HSRNSCKTLKCPKCNWHYKYQQTL+ HM+EKHPE Sbjct: 611 SGIECPKCDTVLGSSRSLGGHMTMMHSRNSCKTLKCPKCNWHYKYQQTLEAHMKEKHPEP 670 Query: 480 NSHCSYCSAGGAHPRLARGESYNCGYKPYRCDVCNYSTTTKGNLSIHMQSDKHLANLQGF 539 C YC G HPRLARGESY CGYKP+RC+VCNYSTTTKGNLSIHMQSDKHL N+Q Sbjct: 671 GGSCVYCKTGQPHPRLARGESYTCGYKPFRCEVCNYSTTTKGNLSIHMQSDKHLNNVQNL 730 Query: 540 QAGPG----GQGSP-PEASLP--PSAGDKEPKTKSSWQCKVCSYETNISRNLRIHMTSEK 592 Q G G G +P P SL + +PK K +W+C+VC YETN++RNLRIHMTSEK Sbjct: 731 QNGNGEQVFGHSAPAPNTSLSGCGTPSPSKPKQKPTWRCEVCDYETNVARNLRIHMTSEK 790 Query: 593 HMQNVLMLHQ-------GLPLGLPPGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQT 645 HM N+++L Q L LGL P + EL+QY+ Q +G Sbjct: 791 HMHNMMLLQQNMKQIQHNLHLGLAP----------------AEAELYQYYLAQNIGL--- 831 Query: 646 PLAGPGLRPDKPLEAQLLLNGFHHVGAPARKFPTSAPGSLSPDAHLPPSQLLGSSSDSLP 705 G++ + P + QL++N F A A APG LG S Sbjct: 832 ----TGMKLENPADPQLMINPFQLDPATAAAL---APG-------------LGELS---- 867 Query: 706 TSPPPDDSLSLKVFRCLVCQAFSTDSLELLLYHCSIGRSLPEAEWKEVAGDTHRCKLCCY 765 P +LK+F+C VC F++DSLE L H S RSLPE EW+ V GD ++CKLC Y Sbjct: 868 ---PYISDPALKLFQCAVCNKFTSDSLEALSVHVSSERSLPEEEWRAVIGDIYQCKLCNY 924 Query: 766 GTQLKANFQLHLKTDKHAQKYQLAAHLREGGGAMGTPSPA-SLGDGAPYGSVSPLHLRCN 824 TQLKANFQLH KTDKH QKYQL AH++EGG + ++G +P+HL+CN Sbjct: 925 NTQLKANFQLHCKTDKHMQKYQLVAHIKEGGKSNEWRLKCIAIG--------NPVHLKCN 976 Query: 825 ICDFESNSKEKMQLHARGAAHEENSQIYK------VRLGAELGLYHCLLCAWETPSRLAV 878 CD+ +NS +K++LH HE ++YK + E Y+C +C + T +L + Sbjct: 977 ACDYYTNSVDKLRLHTTNHRHEAALKLYKHLQKQEGAVNPESCYYYCAVCDYTTKVKLNL 1036 Query: 879 LQHLRTPAHRDAQAQRRLQLLQNGPTTEE-GLAALQSILSFSHGQLRTPA------EVVP 931 +QH+R+ H+ + R+LQL Q G EE L+ + + +L T + + Sbjct: 1037 VQHVRSVKHQQTEGLRKLQLHQQGLAPEEDNLSEIFFVKDCPPNELETASLGARTCDDDL 1096 Query: 932 AEAGNSQPGTIDPEGTGEEPARGCQRLHLKKKKKKKKEWGRASAASKGLCDGGSHPSLTL 991 E G I P E+ + + K K+ + ++ L T Sbjct: 1097 TEQHEEAEGAIKPTAVAEDDEKDTSERDNSEGKNSNKDSVSVAGGTQPLLLAKEEDVATK 1156 Query: 992 RPLP-----ICSLQVYCCPYCSFLSPESSQVRAHTLSQHAVQPKYRCPLCQEQLVGRPAL 1046 R P C Q Y CPYC++ S + S+++ H LSQH+VQP CPLCQ+ L + L Sbjct: 1157 RSKPTEDNKFCHEQFYQCPYCNYNSRDQSRIQMHVLSQHSVQPVICCPLCQDVLSNKMHL 1216 Query: 1047 HFHLSHLHNVVPECVEKLLLVVSTGWVRTVQQDLIRAVQEGRKRQGYSGRCMCWGQGAF 1105 HL+HLH+V P+CVEKLL+ V V L+ A + + G G + Sbjct: 1217 QLHLTHLHSVSPDCVEKLLMTVPVPDVMMPNSMLLPAAASEKSERDTPAAVTAEGSGKY 1275 Score = 270 bits (691), Expect = 1e-71 Identities = 204/641 (31%), Positives = 283/641 (44%), Gaps = 140/641 (21%) Query: 2167 SSASSLAEPESPGAGGTSGGPGGGTGVPDGMGQRRYRTQMSSLQLKIMKACYEAYRTPTM 2226 S SS+A+P SP G+S + D G +R+RTQMS+LQLK++KAC+ YRTPTM Sbjct: 2854 SETSSIADPSSPNPFGSSNPFKSKSN--DRPGHKRFRTQMSNLQLKVLKACFSDYRTPTM 2911 Query: 2227 QECEVLGEEIGLPKRVIQVWFQNARAKEKKAKLQ-GTAAGSTGGSSEGLLAAQRTDCPYC 2285 QECE+LG EIGLPKRV+QVWFQNARAKEKK K+ G G +EG + +C C Sbjct: 2912 QECEMLGNEIGLPKRVVQVWFQNARAKEKKFKINIGKPFMINQGGTEGT----KPECTLC 2967 Query: 2286 DVKYDFYVSCRGHLFSRQHLAKLKEAVRAQLKSES---------------------KCYD 2324 VKY +S R H+FS+QH++K++E V +QL E K D Sbjct: 2968 GVKYSARLSIRDHIFSKQHISKVRETVGSQLDREKDYLAPTTVRQLMAQQELDRIKKASD 3027 Query: 2325 LAPAPEAPPALKAPPATTPASMPLGAAPTLPRLAPVLLSGPALAQPPLGNLAPFNSGPAA 2384 + P + + S+P A P LP L PVLL G G N+ Sbjct: 3028 VLGLTVQQPGMMDSSSLHGISLPT-AYPGLPGLPPVLLPGMNGPSSLPGFPQNSNTLTPP 3086 Query: 2385 SSGLLGLATSVLPTTTVVQTAGPGRPLPQRPMPDQTNTSTAGTTDPVPGPPTEPLGDKVS 2444 +G+LG TS + + ++ P +PL Q P P P P PP+ L + + Sbjct: 3087 GAGMLGFPTSATSSPALSLSSAPTKPLLQTPPPPPP---------PPPPPPSSSLSGQQT 3137 Query: 2445 SERKPVAGPTSSSNDALKNLKA--LKTTVP------------------------------ 2472 ++ + + + +K +K L+ T P Sbjct: 3138 EQQNKESEKKQTKPNKVKKIKEEELEATKPEKHPKKEEKISSALSVLGKVVGETHVDPIQ 3197 Query: 2473 -------------ALLGGQFLPFPLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMN 2519 + +GGQFLP+ +P P + G +QG YF + GM+ LFP Sbjct: 3198 LQALQNAIAGDPASFIGGQFLPYFIPGFASYFTPQLPGT-VQGGYFPPVCGMES-LFPYG 3255 Query: 2520 PMIPQTLIGLLPNALLQP-------------------PPQPPEPTATAPPKPPELPAPGE 2560 P +PQTL GL P ALLQ Q +P K Sbjct: 3256 PTMPQTLAGLSPGALLQQYQQYQQNLQESLQKQQKQQQEQQQKPVQAKTSKVESDQPQNS 3315 Query: 2561 GEAGEVDELLTGSTGISTVD------------------VTHRYLCRQCKMAFDGEAPATA 2602 +A E E + +T + + V + ++CR+C+M F E A Sbjct: 3316 NDASETKEDKSTATESTKEEPQLESKSADFSDTYVVPFVKYEFICRKCQMMFTDEDAAVN 3375 Query: 2603 HQRSFCFFGRGSGGSMPPPLRVPICTYHCLACEVLLSGREALASHLRSSAHRRKAAPPQG 2662 HQ+SFC+FG+ LRVP+ Y CLAC+V +SG EAL+ HL+SS H+ K Sbjct: 3376 HQKSFCYFGQPLIDPQETVLRVPVSKYQCLACDVAISGNEALSQHLQSSLHKEK------ 3429 Query: 2663 GPPISITNAATAASAAVAFAKEEAR-LPHTDSNPKTTTTST 2702 A+ AKE R LPH+ +P TTST Sbjct: 3430 -----------TIKQAMRNAKEHVRLLPHSVCSPNPNTTST 3459 Score = 228 bits (581), Expect = 6e-59 Identities = 211/738 (28%), Positives = 285/738 (38%), Gaps = 209/738 (28%) Query: 1455 PFLSPPPPPLDLHRFPAPLFTPPVLPPFPLVPESLLKLQQQQLLLPFYLHDLKVGPKLTL 1514 P PPPPP PP LPP P P S+ GP Sbjct: 1955 PETPPPPPP------------PPPLPPAPPQPSSM-------------------GPVKIP 1983 Query: 1515 AGPAPVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPSSPPDPLPNEAARTAA 1574 + L P TPPPPP PP PP P PP P P+ + Sbjct: 1984 NTVSTPLQAPPPTPPPPPPPPP----------PP---------PPPPPPPPPSAPPQVQL 2024 Query: 1575 KALLENFGFELVIQYNEGKQAVPPPPTP--PPPEALGGGDKLACGACGKLFSNMLILKTH 1632 L+ F ++ A+PP P +AL C L N L H Sbjct: 2025 PVSLDLPLFPSIMMQPVQHPALPPQLALQLPQMDALSADLTQLCQQQLGLDPNFL---RH 2081 Query: 1633 EEHVHRRFL----PFEALSRYAAQFRKSYDSLYPPLAEPP----------------KPPD 1672 + R + L Y + +AE K Sbjct: 2082 SQFKRPRTRITDDQLKILRAYFDINNSPSEEQIQEMAEKSGLSQKVIKHWFRNTLFKERQ 2141 Query: 1673 GSLDSPVPHLGPPFLVPEPEAGGTRAPEERSRAGGHWPIEEEESSRGNLPPLVPAGRRFS 1732 + DSP PP V E I+ + +S + +R S Sbjct: 2142 RNKDSPYNFSNPPITVLEDIR-----------------IDPQPTSLEHYKSDASFSKRSS 2184 Query: 1733 RTKFTEFQTQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARK---NAC 1789 RT+FT++Q + LQ FF+T+AYPKD E+E+L+++L L +RV+VVWFQNARQKARK N Sbjct: 2185 RTRFTDYQLRVLQDFFDTNAYPKDDEIEQLSTVLNLPTRVIVVWFQNARQKARKSYENQA 2244 Query: 1790 EGGSMPTGGGTGGAS--------GCRRCHATFSCVFELVRHLKK-CYDDQTLEEEEE--- 1837 E T C++C+ F +F+L+ H KK CY D+ + ++E Sbjct: 2245 ETKDNEKRELTNERYIRTSNMQYQCKKCNVVFPRIFDLITHQKKQCYKDEDDDAQDESQT 2304 Query: 1838 ------------------------------------------------EAERGEEEEEVE 1849 E E+ + E Sbjct: 2305 EDSMDATDQVVYKHCTVSGQTDAAKNAAAPAASSGSGTSTPLIPSPKPEPEKTSPKPEYP 2364 Query: 1850 EEEVEEEQGLEPPAGPEGPLPEPPDGEELSQAEATKAG------------GKEPEEKATP 1897 E+ ++ P G + LP + QA + G+ P TP Sbjct: 2365 AEKPKQSDPSPPSQGTKPALPLASTSSDPPQASTAQPQPQPQPPKQPQLIGRPPSASQTP 2424 Query: 1898 SPSPA------------------HTCDQCAISFSSQDLLTSHRRLHFLPS----LQPSAP 1935 PS + CDQC ++F + +L H+ +HFL + L Sbjct: 2425 VPSSPLQISMTSLQNSLPPQLLQYQCDQCTVAFPTLELWQEHQHMHFLAAQNQFLHSPFL 2484 Query: 1936 PQLLDLPLLVFGERNPLV---------------AATSPMPGPP-----LKRKHEDGSLSP 1975 + +D+P ++F NPL+ A++S P LKRK +D + Sbjct: 2485 ERPMDMPYMIFDPNNPLMTGQLLGSSLTQMPPQASSSHTTAPTTVAASLKRKLDDKEDNN 2544 Query: 1976 TGSEAGGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVV 2035 + GG + RDKRLRTTI PEQLEILY Y+ DSNPTRKMLD I+ EVGLKKRVV Sbjct: 2545 CSEKEGGNSGEDQHRDKRLRTTITPEQLEILYEKYLLDSNPTRKMLDHIAREVGLKKRVV 2604 Query: 2036 QVWFQNTRARERKGQFRS 2053 QVWFQNTRARERKGQFR+ Sbjct: 2605 QVWFQNTRARERKGQFRA 2622 Score = 186 bits (473), Expect = 2e-46 Identities = 118/308 (38%), Positives = 158/308 (51%), Gaps = 65/308 (21%) Query: 1275 APPPTMAEEEEGTTGELR---------SAEPAPADS-----------RHPLTYRKTTNFA 1314 A TM++++ G E+ A P +DS + L +RK NF Sbjct: 1426 AESETMSQDDHGLEQEMEREYEVDHEGKASPVGSDSSSIPDDMGSEPKRTLPFRKGPNFT 1485 Query: 1315 LDKFLDPARPYKCTVCKESFTQKNILLVHYNSVSHLHKMKKAAIDPSAPARGEAGAPPTT 1374 ++KFLDP+RPYKCTVCKESFTQKNILLVHYNSVSHLHK+KK + S+P P T Sbjct: 1486 MEKFLDPSRPYKCTVCKESFTQKNILLVHYNSVSHLHKLKKVLQEASSP------VPQET 1539 Query: 1375 TAATD-KPFKCTVCRVSYNQSSTLEIHMRSVLHQTRSRGTKTD------------SKIEG 1421 + TD KP+KC++C V+Y+QSSTLEIHMRSVLHQT++R K + + + Sbjct: 1540 NSNTDNKPYKCSICNVAYSQSSTLEIHMRSVLHQTKARAAKLEPSGHVAGGHSIAANVNS 1599 Query: 1422 PERSQEE--------PKEGETEGEVGTEKKGPDTSGFISGLPFLSPPPPPLDLHR----- 1468 P + + K+ + + +K+ PD IS P PP P + Sbjct: 1600 PGQGMLDSMSLAAVNSKDTHLDAKELNKKQTPD---LISAQPAHHPPQSPAQIQMQLQHE 1656 Query: 1469 -------FPAPLFTPPVLPPFPLVPESLLKLQQQQLLLPFYL--HDLKVGPKLTLAGPAP 1519 F P LP FP+ PE+LL+ QQ Q L PFY+ + +GP L L G A Sbjct: 1657 LQQQAAFFQPQFLNPAFLPHFPMTPEALLQFQQPQFLFPFYIPGTEFSLGPDLGLPGSA- 1715 Query: 1520 VLSLPAAT 1527 +P T Sbjct: 1716 TFGMPGMT 1723 Score = 130 bits (328), Expect = 1e-29 Identities = 79/177 (44%), Positives = 100/177 (56%), Gaps = 12/177 (6%) Query: 1532 PQPPKAE-LAEREWERPPM-AKEGNEAGPSSPPDPLPNEAARTAAKALLENFGFELVIQY 1589 P+ PK E ++E E + K+ PS PP + + A AAKALLENFGFELVIQY Sbjct: 1820 PEKPKQEFISEGEGLKEGKDTKKQKSLEPSIPPPRIASGARGNAAKALLENFGFELVIQY 1879 Query: 1590 NEGKQAVPPPPTPPPPEALGGGDKLACGACGKLFSNMLILKTHEEHVHRRFLPFEALSRY 1649 NE +Q V E DKL CG CGKLFSN+LILK+H+EHVH +F P+ AL ++ Sbjct: 1880 NENRQKVQKKGKSGEGE---NTDKLECGTCGKLFSNVLILKSHQEHVHGQFFPYAALEKF 1936 Query: 1650 AAQFRKSYDSLYP-----PLAEPPKPPDGSLD--SPVPHLGPPFLVPEPEAGGTRAP 1699 A Q+R++YD LYP P PP PP L P P P +P + +AP Sbjct: 1937 ARQYREAYDKLYPISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAP 1993 Score = 65.1 bits (157), Expect = 9e-10 Identities = 56/189 (29%), Positives = 82/189 (43%), Gaps = 41/189 (21%) Query: 2147 PPKAS------PESEACSLSAGDLSDSSASSLAEPESPGAGGTSGGPGGGTGVPDGMGQR 2200 PP+AS P + A SL L D ++ +E E GG SG D + Sbjct: 2515 PPQASSSHTTAPTTVAASLKR-KLDDKEDNNCSEKE----GGNSG--------EDQHRDK 2561 Query: 2201 RYRTQMSSLQLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAKLQ 2260 R RT ++ QL+I+ Y PT + + + E+GL KRV+QVWFQN RA+E+K + + Sbjct: 2562 RLRTTITPEQLEILYEKYLLDSNPTRKMLDHIAREVGLKKRVVQVWFQNTRARERKGQFR 2621 Query: 2261 GTAAGSTGGSSEGLLAAQRTDCPYCDVKYDFYVSCRGHLFSRQHLAKLKEAVRAQLKSES 2320 A CP+C + + H+ SR H + K+A Sbjct: 2622 AVGP-----------AQSHKRCPFCRALFKAKSALESHIRSR-HWNEGKQA--------- 2660 Query: 2321 KCYDLAPAP 2329 Y L P+P Sbjct: 2661 -GYSLPPSP 2668 Score = 60.1 bits (144), Expect = 3e-08 Identities = 53/203 (26%), Positives = 85/203 (41%), Gaps = 18/203 (8%) Query: 2054 TPGGVPSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQP 2113 TP P P PPA P+S+ G V P + P P P P P Sbjct: 1957 TPPPPPPPPPLPPAPPQPSSM-------GPVKIPNTVSTPLQAPPPTPPPPPPPPPPPPP 2009 Query: 2114 FLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESEACSLSAGDLSDSSASSLA 2173 PP + P + P+ L P PS P + P A P A L D + + L Sbjct: 2010 PPPPPPPSAPPQVQLPVSLDLPLFPSIMMQPVQHP-ALPPQLALQLPQMDALSADLTQLC 2068 Query: 2174 EPESPGAGGTSGGPGGGTGVPDGMGQRRYRTQMSSLQLKIMKACYEAYRTPTMQECEVLG 2233 + + G +R RT+++ QLKI++A ++ +P+ ++ + + Sbjct: 2069 QQQL----------GLDPNFLRHSQFKRPRTRITDDQLKILRAYFDINNSPSEEQIQEMA 2118 Query: 2234 EEIGLPKRVIQVWFQNARAKEKK 2256 E+ GL ++VI+ WF+N KE++ Sbjct: 2119 EKSGLSQKVIKHWFRNTLFKERQ 2141 Score = 57.0 bits (136), Expect = 2e-07 Identities = 31/78 (39%), Positives = 45/78 (57%), Gaps = 5/78 (6%) Query: 1971 GSLSPTGSEAGGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGL 2030 GS +P S++ + P KR RT + QL++L + PT + + + E+GL Sbjct: 2869 GSSNPFKSKSN-----DRPGHKRFRTQMSNLQLKVLKACFSDYRTPTMQECEMLGNEIGL 2923 Query: 2031 KKRVVQVWFQNTRARERK 2048 KRVVQVWFQN RA+E+K Sbjct: 2924 PKRVVQVWFQNARAKEKK 2941 Score = 53.1 bits (126), Expect = 4e-06 Identities = 41/135 (30%), Positives = 57/135 (42%), Gaps = 11/135 (8%) Query: 1692 EAGGTRAPEERSRAGGHWPIEEEESSRGNLPPLVPAGRRFSRTKFTEFQTQALQSFFETS 1751 E P + G P + + + R P +RF RT+ + Q + L++ F Sbjct: 2855 ETSSIADPSSPNPFGSSNPFKSKSNDR-------PGHKRF-RTQMSNLQLKVLKACFSDY 2906 Query: 1752 AYPKDGEVERLASLLGLASRVVVVWFQNARQKARKNACEGGS--MPTGGGTGGAS-GCRR 1808 P E E L + +GL RVV VWFQNAR K +K G M GGT G C Sbjct: 2907 RTPTMQECEMLGNEIGLPKRVVQVWFQNARAKEKKFKINIGKPFMINQGGTEGTKPECTL 2966 Query: 1809 CHATFSCVFELVRHL 1823 C +S + H+ Sbjct: 2967 CGVKYSARLSIRDHI 2981 Score = 51.2 bits (121), Expect = 1e-05 Identities = 72/309 (23%), Positives = 116/309 (37%), Gaps = 46/309 (14%) Query: 1773 VVVWFQNARQKARKNACEGGSMPTGGGTGGASGCRRCHATFSCVFELVRHLKKCYDDQTL 1832 +V+ + RQK +K G G C C FS V L H + + Sbjct: 1875 LVIQYNENRQKVQKKGKSGE-----GENTDKLECGTCGKLFSNVLILKSHQEHVHGQFFP 1929 Query: 1833 EEEEEEAERGEEEEEVEEEEVEEEQGLEPPAGPEGPL--PEPPDGEELSQAE-----ATK 1885 E+ R E + + PP P P P PP + + +T Sbjct: 1930 YAALEKFARQYREAYDKLYPISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTP 1989 Query: 1886 AGGKEPEEKATPSPSPAHTCDQCAISFSSQDLLTSHRRLHFLPSLQPSAPPQL-----LD 1940 P P P P P PSAPPQ+ LD Sbjct: 1990 LQAPPPTPPPPPPPPPPPPPPP--------------------PPPPPSAPPQVQLPVSLD 2029 Query: 1941 LPLLVFGERNPLVAATSPMPGPPLKRKHEDGSLSPTGSEAGGGGEGEPP------RDKRL 1994 LPL P+ P P L+ D +LS ++ G P + KR Sbjct: 2030 LPLFPSIMMQPVQHPALP-PQLALQLPQMD-ALSADLTQLCQQQLGLDPNFLRHSQFKRP 2087 Query: 1995 RTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQNTRARERKGQFRST 2054 RT I +QL+IL ++ +++P+ + + ++E+ GL ++V++ WF+NT +ER+ + + + Sbjct: 2088 RTRITDDQLKILRAYFDINNSPSEEQIQEMAEKSGLSQKVIKHWFRNTLFKERQ-RNKDS 2146 Query: 2055 PGGVPSPAV 2063 P +P + Sbjct: 2147 PYNFSNPPI 2155 Score = 50.1 bits (118), Expect = 3e-05 Identities = 92/450 (20%), Positives = 146/450 (32%), Gaps = 73/450 (16%) Query: 1382 FKCTVCRVSYNQSSTLEIHMRSVLHQTRSRGTKTDSKIEGPERSQEEP--KEGETEGEVG 1439 ++C C V + + L H + ++ + +S+ E + ++ K G+ Sbjct: 2267 YQCKKCNVVFPRIFDLITHQKKQCYKDEDDDAQDESQTEDSMDATDQVVYKHCTVSGQTD 2326 Query: 1440 TEKKGPD---TSGFISGLPFLSPPPPPLDLHRFPAPLFTPPVLPPFPLVPESLLKLQQQQ 1496 K +SG + P + P P P P P P K Sbjct: 2327 AAKNAAAPAASSGSGTSTPLIPSPKPE------------PEKTSPKPEYPAEKPKQSD-- 2372 Query: 1497 LLLPFYLHDLKVGPKLTLAGPAPVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEA 1556 P G P L L A+T PPQ A+ + +PP + Sbjct: 2373 -------------PSPPSQGTKPALPL-ASTSSDPPQASTAQ--PQPQPQPPKQPQLIGR 2416 Query: 1557 GPSSPPDPLPNEAARTAAKALLENFGFELVIQYNEGKQAVPPPPTPPPPEALGGGDKLAC 1616 PS+ P+P+ + + +L + PP+ L + C Sbjct: 2417 PPSASQTPVPSSPLQISMTSLQNSL----------------------PPQLL----QYQC 2450 Query: 1617 GACGKLFSNMLILKTHEEHVHRRFLPFEALSRYAAQFRKSYDSLYPPLAEPPKP--PDGS 1674 C F L+ +EH H FL + ++ + D Y + +P P Sbjct: 2451 DQCTVAFPT---LELWQEHQHMHFLAAQNQFLHSPFLERPMDMPYM-IFDPNNPLMTGQL 2506 Query: 1675 LDSPVPHLGPPFLVPEPEAGGTRAPEERSRAGGHWPIEEEESSRGNLPPLVPAGRRFSRT 1734 L S + + P A T A + + E GN +R RT Sbjct: 2507 LGSSLTQMPPQASSSHTTAPTTVAASLKRKLDDKEDNNCSEKEGGNSGEDQHRDKRL-RT 2565 Query: 1735 KFTEFQTQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARKNACEGGSM 1794 T Q + L + + P ++ +A +GL RVV VWFQN R + RK G Sbjct: 2566 TITPEQLEILYEKYLLDSNPTRKMLDHIAREVGLKKRVVQVWFQNTRARERK-----GQF 2620 Query: 1795 PTGGGTGGASGCRRCHATFSCVFELVRHLK 1824 G C C A F L H++ Sbjct: 2621 RAVGPAQSHKRCPFCRALFKAKSALESHIR 2650 Score = 49.3 bits (116), Expect = 5e-05 Identities = 88/377 (23%), Positives = 141/377 (37%), Gaps = 57/377 (15%) Query: 2199 QRRYRTQMSSLQLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAK----- 2253 +R RT+ + QL++++ ++ P E E L + LP RVI VWFQNAR K Sbjct: 2181 KRSSRTRFTDYQLRVLQDFFDTNAYPKDDEIEQLSTVLNLPTRVIVVWFQNARQKARKSY 2240 Query: 2254 EKKAKLQGTAAGSTGGSSEGLLAAQRTDCPYCDVKYDFYVSCRGHLFSR---------QH 2304 E +A+ + + + C C+V + H + Q Sbjct: 2241 ENQAETKDNEKRELTNERYIRTSNMQYQCKKCNVVFPRIFDLITHQKKQCYKDEDDDAQD 2300 Query: 2305 LAKLKEAVRAQLKSESKCYDLAPAPEAPPALKAPPATTPASMPLGAAPTLPRLAPVLLSG 2364 ++ ++++ A + K ++ +A AP A++ + P+ P+ P S Sbjct: 2301 ESQTEDSMDATDQVVYKHCTVSGQTDAAKNAAAPAASSGSGTSTPLIPS-PKPEPEKTS- 2358 Query: 2365 PALAQPPLGNLAPFNSGPAASSGLLGLATSVLPTTTVVQTAGPGRPLPQRPMPDQTNTST 2424 +P P S P+ S Q P PL D ST Sbjct: 2359 ---PKPEYPAEKPKQSDPSPPS----------------QGTKPALPLAS-TSSDPPQAST 2398 Query: 2425 AGTTDPVPGPPTEP--LGDKVSSERKPV-AGPTSSSNDALKNLKALKTTVPALLGGQ--- 2478 A P P PP +P +G S+ + PV + P S +L+N + P LL Q Sbjct: 2399 A-QPQPQPQPPKQPQLIGRPPSASQTPVPSSPLQISMTSLQN-----SLPPQLLQYQCDQ 2452 Query: 2479 -FLPFPLPPAGGTAPPAVF----GPQLQGAYFQQLYGMKKGLF-PMNPMIPQTLIGLLPN 2532 + FP F L + ++ M +F P NP++ L+G + Sbjct: 2453 CTVAFPTLELWQEHQHMHFLAAQNQFLHSPFLERPMDMPYMIFDPNNPLMTGQLLG---S 2509 Query: 2533 ALLQPPPQPPEPTATAP 2549 +L Q PPQ TAP Sbjct: 2510 SLTQMPPQASSSHTTAP 2526 Score = 47.4 bits (111), Expect = 2e-04 Identities = 47/189 (24%), Positives = 71/189 (37%), Gaps = 23/189 (12%) Query: 1323 RPYKCTVCKESFTQKNILLVHYNSVSHLHKMKKAAIDPSAPARGEAGAPPTT------TA 1376 +P++C VC S T K L +H S HL+ ++ G + P T T Sbjct: 697 KPFRCEVCNYSTTTKGNLSIHMQSDKHLNNVQNLQNGNGEQVFGHSAPAPNTSLSGCGTP 756 Query: 1377 ATDKP-----FKCTVCRVSYNQSSTLEIHMRSVLHQTRSRGTKTDSK-IEGPERSQEEPK 1430 + KP ++C VC N + L IHM S H + + K I+ P Sbjct: 757 SPSKPKQKPTWRCEVCDYETNVARNLRIHMTSEKHMHNMMLLQQNMKQIQHNLHLGLAPA 816 Query: 1431 EGETEGEVGTEKKGPDTSGFISGLPFLSPPPPPLDLHRFPAPLFTPPVLPP-----FPLV 1485 E E + G ++G+ +P P L ++ F T L P P + Sbjct: 817 EAELYQYYLAQNIG------LTGMKLENPADPQLMINPFQLDPATAAALAPGLGELSPYI 870 Query: 1486 PESLLKLQQ 1494 + LKL Q Sbjct: 871 SDPALKLFQ 879 Score = 46.6 bits (109), Expect = 3e-04 Identities = 71/323 (21%), Positives = 107/323 (33%), Gaps = 41/323 (12%) Query: 380 EEDGGLCPPLNQSSPTSKEGGTLPAPVGSPEDPSDPPQPYRLADDYTPAPAAFQGLSLSS 439 ++D GL + + EG +PVGS D S P DD P Sbjct: 1433 QDDHGLEQEMEREYEVDHEGKA--SPVGS--DSSSIP------DDMGSEPKRTLPFRKGP 1482 Query: 440 HMSLLHSRNSCKTLKCPKCNWHYKYQQTLDVHMREKHPESNSHCSYCSAGGAHPRLARGE 499 + ++ + + KC C + + L VH S+ H A + + Sbjct: 1483 NFTMEKFLDPSRPYKCTVCKESFTQKNILLVHYNSV---SHLHKLKKVLQEASSPVPQET 1539 Query: 500 SYNCGYKPYRCDVCNYSTTTKGNLSIHMQSDKHLANLQGFQAGPGGQGSPPEASLPPSAG 559 + N KPY+C +CN + + L IHM+S H + + P G + + Sbjct: 1540 NSNTDNKPYKCSICNVAYSQSSTLEIHMRSVLHQTKARAAKLEPSGHVAGGHSIAANVNS 1599 Query: 560 DKEPKTKSSWQCKVCSYETNI-SRNLRIHMTSEKHMQNVLMLHQGLPLGLPPGLMGPGPP 618 + S V S +T++ ++ L T P L+ P Sbjct: 1600 PGQGMLDSMSLAAVNSKDTHLDAKELNKKQT--------------------PDLISAQPA 1639 Query: 619 PPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRPDKPLEAQLLLNGFHHVGAPARKFP 678 P +P Q+ Q Q P P P+ + LL P FP Sbjct: 1640 HHPPQSPAQIQMQLQHELQQQAAFFQPQFLNPAFLPHFPMTPEALL----QFQQPQFLFP 1695 Query: 679 TSAPG---SLSPDAHLPPSQLLG 698 PG SL PD LP S G Sbjct: 1696 FYIPGTEFSLGPDLGLPGSATFG 1718 Score = 45.4 bits (106), Expect = 7e-04 Identities = 60/226 (26%), Positives = 88/226 (38%), Gaps = 29/226 (12%) Query: 1352 KMKKAAIDPSAPARGEAGAPPTTTAATDKPFKCTVCRVSYNQSSTLEIHMRSVLHQTRSR 1411 K KK I+ P G T KP +CT+C V Y+ ++ H+ S H ++ R Sbjct: 2938 KEKKFKINIGKPFMINQGGTEGT-----KP-ECTLCGVKYSARLSIRDHIFSKQHISKVR 2991 Query: 1412 GTKTDSKIEGPERSQEEP---KEGETEGEVGTEKKGPDTSGFI---------SGLPFLSP 1459 T S+++ E+ P ++ + E+ KK D G S L +S Sbjct: 2992 ET-VGSQLDR-EKDYLAPTTVRQLMAQQELDRIKKASDVLGLTVQQPGMMDSSSLHGISL 3049 Query: 1460 PPPPLDLHRFPAPLFT----PPVLPPFPLVPESLLKLQQQQLLLPFYLHDLKVGPKLTL- 1514 P L P L P LP FP +L L P P L+L Sbjct: 3050 PTAYPGLPGLPPVLLPGMNGPSSLPGFPQNSNTLTPPGAGMLGFPT---SATSSPALSLS 3106 Query: 1515 -AGPAPVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPS 1559 A P+L P PPPPP PP + L+ ++ E+ E + P+ Sbjct: 3107 SAPTKPLLQTPPPPPPPPPPPPSSSLSGQQTEQQNKESEKKQTKPN 3152 Score = 35.8 bits (81), Expect = 0.59 Identities = 21/65 (32%), Positives = 25/65 (38%), Gaps = 10/65 (15%) Query: 1227 TPEASPDPLPEPPL----------ASVEVPDKPSGSPGQPPSPAPSPVPEPDAQAEDVAP 1276 +PE P P P PPL V++P+ S PP P P P P P Sbjct: 1954 SPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPPPPPPP 2013 Query: 1277 PPTMA 1281 PP A Sbjct: 2014 PPPSA 2018 Score = 35.4 bits (80), Expect = 0.77 Identities = 59/266 (22%), Positives = 102/266 (38%), Gaps = 43/266 (16%) Query: 2120 EATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPE-----SEACSLSAGDLSDSSASSLAE 2174 +AT P +P PPPP +++ + E S C + S A ++E Sbjct: 1759 QATQPQLQPQKQQQQPPPPQQQQQQQASKLLKQEQSNIVSADCQIMKDVPSYKEAEDISE 1818 Query: 2175 -PESPGAGGTSGGPGGGTGVPDGMGQRRYRTQMSSLQLKIMKACYEAYRTPTMQECEVLG 2233 PE P S G G + +G ++ ++ S+ + + + L Sbjct: 1819 KPEKPKQEFISEGEG----LKEGKDTKKQKSLEPSIPPPRIASGARG------NAAKALL 1868 Query: 2234 EEIGLPKRVIQVWFQNARAKEKKAKLQGTAAGSTGGSSEGLLAAQRTDCPYCDVKYDFYV 2293 E G + VIQ + +N + +KK K G E + +C C + + Sbjct: 1869 ENFGF-ELVIQ-YNENRQKVQKKGK---------SGEGEN---TDKLECGTCGKLFSNVL 1914 Query: 2294 SCRGHLFSRQHL-------AKLKEAVRAQLKSESKCYDLAPA-PEAPPALKAPPATTPAS 2345 + H ++H+ A L++ R ++ K Y ++P+ PE PP PP P + Sbjct: 1915 ILKSH---QEHVHGQFFPYAALEKFARQYREAYDKLYPISPSSPETPPP-PPPPPPLPPA 1970 Query: 2346 MPLGAAPTLPRLAPVLLSGPALAQPP 2371 P ++ P P +S P A PP Sbjct: 1971 PPQPSSMG-PVKIPNTVSTPLQAPPP 1995 Score = 35.4 bits (80), Expect = 0.77 Identities = 23/69 (33%), Positives = 28/69 (40%), Gaps = 10/69 (14%) Query: 605 PLGLPPGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRPDKPLEAQLLL 664 PL PP P PPPPP P PP P A Q Q P++ D PL +++ Sbjct: 1989 PLQAPPPTPPPPPPPPPPPPPPPPPP-----PPSAPPQVQLPVS-----LDLPLFPSIMM 2038 Query: 665 NGFHHVGAP 673 H P Sbjct: 2039 QPVQHPALP 2047 Score = 35.0 bits (79), Expect = 1.0 Identities = 23/87 (26%), Positives = 29/87 (33%), Gaps = 27/87 (31%) Query: 1519 PVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPSSPPDPLPNEAARTAAKALL 1578 P+ TPPPPP PP PP + + GP P+ + Sbjct: 1949 PISPSSPETPPPPPPPPPL---------PPAPPQPSSMGPVKIPNTVSTP---------- 1989 Query: 1579 ENFGFELVIQYNEGKQAVPPPPTPPPP 1605 +Q PPPP PPPP Sbjct: 1990 --------LQAPPPTPPPPPPPPPPPP 2008 Score = 35.0 bits (79), Expect = 1.0 Identities = 48/199 (24%), Positives = 71/199 (35%), Gaps = 21/199 (10%) Query: 244 LGFSKPQ-AFMDHTQSHGVKLTPAQYQGLSGSPAVLQEGDEGCKALISFLEPKLPARPSS 302 LG + Q MD + HG+ L P Y GL G P VL G G +L F + P Sbjct: 3029 LGLTVQQPGMMDSSSLHGISL-PTAYPGLPGLPPVLLPGMNGPSSLPGFPQNSNTLTPPG 3087 Query: 303 ----DIPLDNSSTVNMEANVAQTEDGPPEAEVQALILLDEEVMALSPPSPPTATWDPSPT 358 P +S+ + + A T+ +L PP PP+++ T Sbjct: 3088 AGMLGFPTSATSSPALSLSSAPTKP----------LLQTPPPPPPPPPPPPSSSLSGQQT 3137 Query: 359 QAKESPVAAGEAGPDWFPEGQEEDGGLCPPLNQSSPTSKEGGTLPA---PVGSPEDPSDP 415 + + + P+ + +EE+ P K L VG E DP Sbjct: 3138 EQQNKESEKKQTKPNKVKKIKEEELEATKPEKHPKKEEKISSALSVLGKVVG--ETHVDP 3195 Query: 416 PQPYRLADDYTPAPAAFQG 434 Q L + PA+F G Sbjct: 3196 IQLQALQNAIAGDPASFIG 3214 Score = 34.7 bits (78), Expect = 1.3 Identities = 21/61 (34%), Positives = 33/61 (54%), Gaps = 3/61 (4%) Query: 238 LCLLCRLGFSKPQAFMDH-TQSHGVKLTPAQYQGLSGS--PAVLQEGDEGCKALISFLEP 294 +C LC+L F ++F+ H H + L + + LS A++Q + + LISFLEP Sbjct: 279 MCFLCKLSFGYIRSFVTHAVHDHRMTLNDEEQKLLSNKCVSAIIQGIGKDKEPLISFLEP 338 Query: 295 K 295 K Sbjct: 339 K 339 Score = 34.7 bits (78), Expect = 1.3 Identities = 24/79 (30%), Positives = 33/79 (41%), Gaps = 26/79 (32%) Query: 2477 GQFLPFPLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNPMIPQTLIGLLPNALLQ 2536 GQF P+ A F Q + AY + L+P++P P+T Sbjct: 1925 GQFFPY--------AALEKFARQYREAYDK--------LYPISPSSPET----------P 1958 Query: 2537 PPPQPPEPTATAPPKPPEL 2555 PPP PP P APP+P + Sbjct: 1959 PPPPPPPPLPPAPPQPSSM 1977 Score = 34.7 bits (78), Expect = 1.3 Identities = 19/51 (37%), Positives = 24/51 (47%), Gaps = 8/51 (15%) Query: 1218 LSPLEGPNL--TPEASPDPLPEPPLASVEVPDKPSGSPGQPPSPAPSPVPE 1266 + P++ PN TP +P P P PP P P P PP P PS P+ Sbjct: 1977 MGPVKIPNTVSTPLQAPPPTPPPP------PPPPPPPPPPPPPPPPSAPPQ 2021 Score = 34.3 bits (77), Expect = 1.7 Identities = 33/107 (30%), Positives = 42/107 (39%), Gaps = 21/107 (19%) Query: 2055 PGGVPSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAFPY-----PTATLAS 2109 PG P V P P+SLP F + P FP P +L+S Sbjct: 3054 PGLPGLPPVLLPGMNGPSSLPGFP------QNSNTLTPPGAGMLGFPTSATSSPALSLSS 3107 Query: 2110 GP-QPFLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESE 2155 P +P L T P P PP PPPPPS ++ + + ESE Sbjct: 3108 APTKPLLQ-----TPPPPPPP----PPPPPSSSLSGQQTEQQNKESE 3145 Score = 33.9 bits (76), Expect = 2.2 Identities = 49/250 (19%), Positives = 90/250 (36%), Gaps = 26/250 (10%) Query: 822 RCNICDFESNSKEKMQLHARGAAHEENSQIYKVRLGAELGLYHCLLCAWETPSRLAVLQH 881 +C C++ S + ++Q+H + H I C LC +++ + H Sbjct: 1173 QCPYCNYNSRDQSRIQMHVL-SQHSVQPVIC------------CPLCQDVLSNKMHLQLH 1219 Query: 882 LRTPAHRDAQAQRRLQLLQNGPTTEEGLAALQSILSFSHGQLRTPAEVVPAEAG--NSQP 939 L +L + P + L + + TPA V +G + + Sbjct: 1220 LTHLHSVSPDCVEKLLMTVPVPDVMMPNSMLLPAAASEKSERDTPAAVTAEGSGKYSGES 1279 Query: 940 GTIDPEGTGEEPARGCQRLHLKKKKKKKK-----EWGRASAASKGLCD---GGSHPSLTL 991 D G E ++ + +++K K+ EW + S+ + D + Sbjct: 1280 PMDDKSMAGLEDSKANVEVKNEEQKPTKEPLEVSEWNKNSSKDVKIPDTLQDQLNEQQKR 1339 Query: 992 RPLPICSLQVYC--CPYCSFLSPESSQVRAHTLSQHAVQPKYRCPLCQEQLVGRPALHFH 1049 +PL + VY C +CS +++ H+ HA++ C LCQ AL H Sbjct: 1340 QPLSVSDRHVYKYRCNHCSLAFKTMQKLQIHS-QYHAIRAATMCNLCQRSFRTFQALKKH 1398 Query: 1050 LSHLHNVVPE 1059 L H + E Sbjct: 1399 LEAGHPELSE 1408 Score = 33.5 bits (75), Expect = 2.9 Identities = 15/38 (39%), Positives = 17/38 (44%) Query: 2521 MIPQTLIGLLPNALLQPPPQPPEPTATAPPKPPELPAP 2558 M P + + L PPP PP P PP PP P P Sbjct: 1977 MGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPPPPPPPP 2014 Score = 32.7 bits (73), Expect = 5.0 Identities = 14/34 (41%), Positives = 16/34 (47%) Query: 2115 LPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPP 2148 + P T P P PP PL P PP GP + P Sbjct: 1950 ISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIP 1983 Score = 32.3 bits (72), Expect = 6.5 Identities = 37/147 (25%), Positives = 55/147 (37%), Gaps = 23/147 (15%) Query: 815 SVSPLHL---RCNICDFESNSKEKMQLHARGAAHEENSQIYKVRLGAELGLYHCLLCAWE 871 SVS H+ RCN C + +K+Q+H SQ + +R C LC Sbjct: 1343 SVSDRHVYKYRCNHCSLAFKTMQKLQIH---------SQYHAIRAAT-----MCNLCQRS 1388 Query: 872 TPSRLAVLQHLRTPAHRDAQAQRRLQLLQNGPTTEEGLAALQSILSFSHG-QLRTPAEVV 930 + A+ +HL H + QL + P E A +++ HG + E Sbjct: 1389 FRTFQALKKHLEA-GHPELSEAELQQLYASLPVNGELWAESETMSQDDHGLEQEMEREYE 1447 Query: 931 PAEAGNSQPGTID----PEGTGEEPAR 953 G + P D P+ G EP R Sbjct: 1448 VDHEGKASPVGSDSSSIPDDMGSEPKR 1474 Score = 32.3 bits (72), Expect = 6.5 Identities = 23/75 (30%), Positives = 25/75 (33%), Gaps = 16/75 (21%) Query: 2483 PLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNPMIPQTLIGLLPNALLQPPPQPP 2542 P PP PPA P G IP T+ L PPP PP Sbjct: 1959 PPPPPPPPLPPAPPQPSSMGPV----------------KIPNTVSTPLQAPPPTPPPPPP 2002 Query: 2543 EPTATAPPKPPELPA 2557 P PP PP P+ Sbjct: 2003 PPPPPPPPPPPPPPS 2017 Score = 32.0 bits (71), Expect = 8.5 Identities = 30/138 (21%), Positives = 52/138 (37%), Gaps = 21/138 (15%) Query: 1803 ASGCRRCHATFSCVFELVRHLKKCYDDQTLEEEEE-------------------EAERGE 1843 A+ C C +F L +HL+ + + + E ++ + + G Sbjct: 1379 ATMCNLCQRSFRTFQALKKHLEAGHPELSEAELQQLYASLPVNGELWAESETMSQDDHGL 1438 Query: 1844 EEEEVEEEEVEEEQGLEPPAGPEGPLPEPPDGEELSQAEATKAGGKEPEEKATPSPSPAH 1903 E+E E EV+ E P +P+ G E + + G EK PS + Sbjct: 1439 EQEMEREYEVDHEGKASPVGSDSSSIPDDM-GSEPKRTLPFRKGPNFTMEKFL-DPSRPY 1496 Query: 1904 TCDQCAISFSSQDLLTSH 1921 C C SF+ +++L H Sbjct: 1497 KCTVCKESFTQKNILLVH 1514 >gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens] Length = 1003 Score = 78.2 bits (191), Expect = 1e-13 Identities = 78/261 (29%), Positives = 103/261 (39%), Gaps = 25/261 (9%) Query: 2313 RAQLKSESKCYDLAPA---PEAPPALKAPPATTPASMPLGAAPTLPRLAPVLLSGPALAQ 2369 RAQ S S L P+ P PP + P + P P P S P +Q Sbjct: 347 RAQAPSASHSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQ 406 Query: 2370 PPLGNLAPF----NSGPAASSGLLGLATSV--LPTTTVVQTAGPGRPLPQRPMPDQTNTS 2423 P L ++ GP+ S G L S LP + + P P P+ P+ + Sbjct: 407 PILPSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSP--PQPRHPIQPSLPGT 464 Query: 2424 TAGTTDPVPGPPTEPLGDKVSSERKPVAGPTSSSNDALKNLKALKTTVPALLGGQFLPFP 2483 T+G+ VPG P P K PV S ++ L +P L GG+ PFP Sbjct: 465 TSGSLSSVPGAPAPPAASKAPVVPSPVL---QSPSEGLGMGAGPACPLPPLAGGEAFPFP 521 Query: 2484 LPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNPMIPQTLIGLLPNALLQPPPQP-- 2541 P G A F P + GA L G P +P++ +L G+L QPPP+P Sbjct: 522 SPEQGLALSGAGF-PGMLGALPLPL---SLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLL 577 Query: 2542 PEPTATAPPKPPELPAPGEGE 2562 P P PP APGE E Sbjct: 578 PPPGGPGPPL-----APGEPE 593 Score = 48.1 bits (113), Expect = 1e-04 Identities = 87/337 (25%), Positives = 117/337 (34%), Gaps = 58/337 (17%) Query: 2065 PPATATPASLPKFN-LLLGKVDDGTGREAPKREAPAFPYPTATLASGPQPFLPPGKEATT 2123 P + P P N L G + G G+ P+ P P P GP P L PG+ Sbjct: 544 PLSLGQPPPSPLLNHSLFGVLTGGGGQPPPE---PLLPPP-----GGPGPPLAPGE---- 591 Query: 2124 PTPEPPLPL---LPPPPPSEEEGPEEPPKASPESEACSLSAGDLSDSSASSLAEPESPGA 2180 PE P L L PPPPS+ PP ++P S + L+ + E + GA Sbjct: 592 --PEGPSLLVASLLPPPPSDLL----PPPSAPPSNLLASFLPLLALGPTAGDGEGSAEGA 645 Query: 2181 GGTSGGPGGGTG--VPDGMGQRRYRTQMSSLQLKIMKACYEAYRTPTMQECEVLGEEIGL 2238 GG SG P G G P + +L ++ A + Q C + + G Sbjct: 646 GGPSGEPFSGLGDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAPQPGP 705 Query: 2239 PKRVIQVWFQNARAKEKKAKLQGTAAGSTGGSSEGLLAAQRTDCPYCDVKYDFYVSCRGH 2298 P + TA G SS G A + P + S G Sbjct: 706 PTSSVT-----------------TATTDPGASSLG-KAPSNSGRPPQLLSPLLGASLLGD 747 Query: 2299 LFSRQHLAKLKEAVRAQLKSESKCYDLAPAPEAPPALKAPPATTPASMPLGA-------- 2350 L S L A+ + L+ + P APP + AS PL Sbjct: 748 LSS---LTSSPGALPSLLQPPGPLLSGQLGLQLLPGGGAPPPLSEASSPLACLLQSLQIP 804 Query: 2351 -----APTLPRLAPVLLSGPALAQPPLGNLAPFNSGP 2382 AP LP +P P A+PPL LAP + P Sbjct: 805 PEQPEAPCLPPESPASALEPEPARPPLSALAPPHGSP 841 Score = 44.7 bits (104), Expect = 0.001 Identities = 114/462 (24%), Positives = 151/462 (32%), Gaps = 106/462 (22%) Query: 9 TTGTTPSPGHN-APSLPSDTFSSSTPSDPVTKDPPAASSTSENMRSSEPGGQLLESGCGL 67 ++G+ P P H PSLP T S S S P PPAAS + Sbjct: 446 SSGSPPQPRHPIQPSLPGTT-SGSLSSVPGAPAPPAASKAP------------------V 486 Query: 68 VPPKEIGEPQEGPDCGHFPPNDPGVEKDKEQEEEEEGLPPMDLSNHLFFTAGGEAYLVAK 127 VP + P EG G P LPP+ AGGEA+ Sbjct: 487 VPSPVLQSPSEGLGMGAGPACP---------------LPPL---------AGGEAF---P 519 Query: 128 LSLPGGSELLLPKGFPWGEAGIKEEPSLPF-LAYPPPSHLTALHIQHGFDPIQGFSSSDQ 186 P L GFP G+ LP L PPPS L H G G + Sbjct: 520 FPSPEQGLALSGAGFP----GMLGALPLPLSLGQPPPSPLLN-HSLFGVLTGGGGQPPPE 574 Query: 187 ILSHDTSAPSP--AACEERHGAFWSYQLAPNPPGD---PKDGPMGNSGGNHVAVFWLCLL 241 L P P A E + L P PP D P P N + +L LL Sbjct: 575 PLLPPPGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAPPSN-----LLASFLPLL 629 Query: 242 CRLGFSKPQAFMDHTQSHGV------------KLTPAQYQGLSGSPAVLQ---------- 279 LG P A + G L+P + LS P ++ Sbjct: 630 A-LG---PTAGDGEGSAEGAGGPSGEPFSGLGDLSPLLFPPLSAPPTLIALNSALLAATL 685 Query: 280 EGDEGCKALISFLEPKLPARPSSDIPLDNSSTVNMEANVAQTEDGPPEAEVQAL----IL 335 + G L P P+S + + A + G P + L +L Sbjct: 686 DPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLL 745 Query: 336 LDEEVMALSPPSPPTATWDPSPTQAKESPVAAGEAGPDWFPEGQEEDGGLCPPLNQ-SSP 394 D + SP + P+ P P+ +G+ G P GG PPL++ SSP Sbjct: 746 GDLSSLTSSPGALPSLLQPP-------GPLLSGQLGLQLLP-----GGGAPPPLSEASSP 793 Query: 395 TSKEGGTLPAPVGSPEDPSDPPQPYRLADDYTPAPAAFQGLS 436 + +L P PE P PP+ A + PA L+ Sbjct: 794 LACLLQSLQIPPEQPEAPCLPPESPASALEPEPARPPLSALA 835 Score = 42.4 bits (98), Expect = 0.006 Identities = 131/641 (20%), Positives = 192/641 (29%), Gaps = 122/641 (19%) Query: 2059 PSPAVKPPATATPASLPKFNLLLGKVDDGTGREAP------------KREAPAFPYPTAT 2106 P PA +PP ++ LP LG G AP K + P P P+ Sbjct: 282 PGPASQPPVSSATMHLPLVLGPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTL 341 Query: 2107 LASGPQPFLPPGKEATTPTPEPPLPLLPPP--PPSEEEGPEEPPKASPESEACSLSAGDL 2164 P+ P +++ P P PP E GP+ P ++ P + A L Sbjct: 342 QGRRPRAQAPSASHSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSL 401 Query: 2165 SDSSASSLAEPESPGAGGTSGGPGGGTGVPDGMGQRRYRTQMSSLQLKIMKACYEAYRTP 2224 + S +P P G P G DG Sbjct: 402 PEPS-----QPILPSVLSLLGLPTPGPSHSDG---------------------------- 428 Query: 2225 TMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAKLQGTAAGSTGGSSEGLLAAQRTDCPY 2284 +LG + LP + + + +Q + G+T GS L + P Sbjct: 429 ---SFNLLGSDAHLPP---PPTLSSGSPPQPRHPIQPSLPGTTSGS---LSSVPGAPAPP 479 Query: 2285 CDVKYDFYVSCRGHLFSRQHLAKLKEAVRAQLKSESKCYDLAPAPEAPPAL--KAPPATT 2342 K A + + Q SE PA PP +A P + Sbjct: 480 AASK-----------------APVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPS 522 Query: 2343 PASMPLGAAPTLPRLAPVLLSGPALAQPPLGNLAPFNSGPAASSGLLGLAT----SVLPT 2398 P + P + L +L QPP P + L G+ T P Sbjct: 523 PEQGLALSGAGFPGMLGALPLPLSLGQPP--------PSPLLNHSLFGVLTGGGGQPPPE 574 Query: 2399 TTVVQTAGPGRPLPQRPMPDQTNTSTAGTTDPVPG----PPTEPLGDKVSSERKPVA-GP 2453 + GPG PL P+ + A P P PP+ P + ++S +A GP Sbjct: 575 PLLPPPGGPGPPLAPGE-PEGPSLLVASLLPPPPSDLLPPPSAPPSNLLASFLPLLALGP 633 Query: 2454 TSSSNDALKNLKALKTTVPALLGGQFLPFPLPPAGGTAPPAVFGPQLQGAYFQQLYGMKK 2513 T+ + + P G P PP +APP + L A Sbjct: 634 TAGDGEGSAEGAGGPSGEPFSGLGDLSPLLFPPL--SAPPTLIA--LNSALLAATLDPPS 689 Query: 2514 GLFPMNPMIPQTLIGLLPNALLQPPPQPPEPTATAPPKPPELPAPGE--GEAGEVDELLT 2571 G P P L P P PP + T P + G+ +G +LL+ Sbjct: 690 GTPPQ------------PCVLSAPQPGPPTSSVTTATTDPGASSLGKAPSNSGRPPQLLS 737 Query: 2572 GSTGISTVDVTHRYLCRQCKMAFDGEAPATAHQRSFCFFGRGS-----GGSMPPPLRVPI 2626 G S + + G P+ G+ GG PPPL Sbjct: 738 PLLGASLLGDL------SSLTSSPGALPSLLQPPGPLLSGQLGLQLLPGGGAPPPLSEAS 791 Query: 2627 CTYHCLACEVLLSGREALASHLRSSAHRRKAAPPQGGPPIS 2667 CL + + + A L + P PP+S Sbjct: 792 SPLACLLQSLQIPPEQPEAPCLPPESPASALEPEPARPPLS 832 Score = 40.4 bits (93), Expect = 0.024 Identities = 82/313 (26%), Positives = 100/313 (31%), Gaps = 101/313 (32%) Query: 2330 EAPPALKAPPATTPASMPLGAAPTLPRLAPVLLSGP-----ALAQPPLGNLAPFNSGPAA 2384 + PP PP P P LAP GP +L PP +L P S P + Sbjct: 570 QPPPEPLLPPPGGPG----------PPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAPPS 619 Query: 2385 SSGLLGLATSVLPTTTVVQTAGPGR--------------------------PLPQRPMPD 2418 + L S LP + TAG G PL P Sbjct: 620 N-----LLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFSGLGDLSPLLFPPLSAPPTLI 674 Query: 2419 QTNTS-TAGTTD--------------PVPGPPT------------EPLGDKVSSERKP-- 2449 N++ A T D P PGPPT LG S+ +P Sbjct: 675 ALNSALLAATLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGASSLGKAPSNSGRPPQ 734 Query: 2450 ---------VAGPTSSSNDALKNLKALKTTVPALLGGQFLPFPLPPAGGTAPPAVFGPQL 2500 + G SS + L +L LL GQ L L P GG PP Sbjct: 735 LLSPLLGASLLGDLSSLTSSPGALPSLLQPPGPLLSGQ-LGLQLLPGGGAPPPLSEASSP 793 Query: 2501 QGAYFQQLYGMKKGLFPMNPMIPQTLIGLLPNALLQPPPQPPEPTATAPPK-PPELPAPG 2559 Q L + P P P L P + L+P P P +A APP P+ P P Sbjct: 794 LACLLQSLQ-----IPPEQPEAP-CLPPESPASALEPEPARPPLSALAPPHGSPDPPVP- 846 Query: 2560 EGEAGEVDELLTG 2572 ELLTG Sbjct: 847 --------ELLTG 851 Score = 37.7 bits (86), Expect = 0.15 Identities = 48/169 (28%), Positives = 58/169 (34%), Gaps = 23/169 (13%) Query: 1444 GPDTSGFISGLPFLSPPPPPLDLHRFPAPLFTPPVLPPFPLVPESLLKLQQQQLLLPFYL 1503 GP TS + + P L + P+ PP L PL+ SLL P L Sbjct: 704 GPPTSSVTTA----TTDPGASSLGKAPSNSGRPPQLLS-PLLGASLLGDLSSLTSSPGAL 758 Query: 1504 HDLKVGPKLTLAGPAPVLSLPAATPPPPPQPPKAELA--EREWERPPMAKEGNEAGPSSP 1561 L P L+G + LP PPP + LA + + PP E P SP Sbjct: 759 PSLLQPPGPLLSGQLGLQLLPGGGAPPPLSEASSPLACLLQSLQIPPEQPEAPCLPPESP 818 Query: 1562 PDPLPNEAARTAAKALLENFGFELVIQYNEGKQAVPPPPTPPPPEALGG 1610 L E AR AL G P PP PE L G Sbjct: 819 ASALEPEPARPPLSALAPPHG----------------SPDPPVPELLTG 851 Score = 37.0 bits (84), Expect = 0.26 Identities = 97/378 (25%), Positives = 127/378 (33%), Gaps = 71/378 (18%) Query: 1861 PPAGP--EGPLPEPPDGEELSQAEATKAG--GKEPEEKATPSPSPAHTCDQCAISFSSQD 1916 PP P GP PP+ +SQA T AG G P A P PS SS Sbjct: 152 PPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLADPVPSGGS---------SSPR 202 Query: 1917 LLTSHRRLHFLPSLQPSAPPQL-LDLPLLVFGE--RNPLV-----------AATSPMPGP 1962 L PS P PP + L+ P +G R+ LV A++SP P Sbjct: 203 FLPRGNA----PSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPSDP 258 Query: 1963 PLKRKHEDGSLSP------TGSEAGGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNP 2016 PL H +L+P A G +PP T LP L L + Sbjct: 259 PLF--HCSDALTPPPLPPSNNLPAHPGPASQPPVSSA--TMHLPLVLGPLGGAPTVEGPG 314 Query: 2017 TRKMLDCISEEVGLKKRVVQVWFQNT-RARERKGQFRSTPGGVPSPAVKPPATATPASLP 2075 L K + + +T + R + Q P S +++P Sbjct: 315 APPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQ---APSASHSSSLRPSQRRPRRPPT 371 Query: 2076 KFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQPFLPPGKEATT----PTPEPPL- 2130 F LL +G G + P+R P P P S P+P P + PTP P Sbjct: 372 VFRLL-----EGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSHS 426 Query: 2131 ----------PLLPPPP------PSEEEGPEEPPKASPESEACSLSAGDLSDSSASSLAE 2174 LPPPP P + P +P S + S G + +AS Sbjct: 427 DGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPV 486 Query: 2175 PESPGAGGTSGGPGGGTG 2192 SP S G G G G Sbjct: 487 VPSPVLQSPSEGLGMGAG 504 Score = 35.4 bits (80), Expect = 0.77 Identities = 34/137 (24%), Positives = 50/137 (36%), Gaps = 13/137 (9%) Query: 2053 STPGGVPSPAV------KPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAFPYPTAT 2106 S+PG SP + PP+ P +P L G G G P+ + + +PT Sbjct: 124 SSPGEGASPQMFHTVSPGPPSARPPCRVPPTTPLNG----GPGSLPPEPPSVSQAFPTL- 178 Query: 2107 LASGPQPFLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESEACSLSAGDLSD 2166 +GP PP P+ P P + P PP S + + + A S Sbjct: 179 --AGPGGLFPPRLADPVPSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSS 236 Query: 2167 SSASSLAEPESPGAGGT 2183 S L P +P A + Sbjct: 237 LVPSDLGSPPAPHASSS 253 Score = 34.7 bits (78), Expect = 1.3 Identities = 38/125 (30%), Positives = 43/125 (34%), Gaps = 30/125 (24%) Query: 604 LPLGLPPGLMGPGPPPPPGATPTSP-----PELFQYFGPQALGQPQTPLAGPGLRPDKPL 658 LP G P P PPPPP + +P L P LG P P A D PL Sbjct: 204 LPRGNAPS---PAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPSDPPL 260 Query: 659 EAQLLLNGFHHVGA------------PARKFPTSAPGSLSPDAHLP--PSQLLGSSSDSL 704 FH A PA P S P S HLP L G+ + Sbjct: 261 --------FHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGPLGGAPTVEG 312 Query: 705 PTSPP 709 P +PP Sbjct: 313 PGAPP 317 Score = 33.9 bits (76), Expect = 2.2 Identities = 44/157 (28%), Positives = 52/157 (33%), Gaps = 21/157 (13%) Query: 1458 SPPPPPLDLHRFPAPLFTPPVLPPFPLVPE-----SLLKLQQQQLLLPFYLHDLKVGPKL 1512 SPP P H A TPP LPP +P S + + LP L L P + Sbjct: 253 SPPSDPPLFHCSDA--LTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGPLGGAPTV 310 Query: 1513 TLAGPAP-----VLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPSSPPDPLPN 1567 G P +LS A PP PP R + P A + PS P Sbjct: 311 EGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSSLRPSQRRPRRPP 370 Query: 1568 EAARTAAKALLENFGFELVIQYNEGKQAVPPPPTPPP 1604 R LLE G Q + P P P P Sbjct: 371 TVFR-----LLEGRG----PQTPRRSRPRAPAPVPQP 398 Score = 33.9 bits (76), Expect = 2.2 Identities = 32/100 (32%), Positives = 41/100 (41%), Gaps = 22/100 (22%) Query: 612 LMGPGPPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRPDKPLEAQLLLNGFHHVG 671 L G GP P + P +P + Q P +L +P P+ L + L L G G Sbjct: 376 LEGRGPQTPRRSRPRAPAPVPQ---PFSLPEPSQPI----------LPSVLSLLGLPTPG 422 Query: 672 APARKFPTSAPGS---LSPDAHLPPSQLLGSSSDSLPTSP 708 P+ + GS L DAHLPP L S S P P Sbjct: 423 ------PSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHP 456 Score = 33.5 bits (75), Expect = 2.9 Identities = 30/108 (27%), Positives = 43/108 (39%), Gaps = 24/108 (22%) Query: 345 PPSPPTATWD-PS--------PTQAKESPVAAGEAGPDWFPEGQEEDGGLCPP----LN- 390 PP PP+ + P+ P + + + G + P + P G PP LN Sbjct: 165 PPEPPSVSQAFPTLAGPGGLFPPRLADPVPSGGSSSPRFLPRGNAPSPAPPPPPAISLNA 224 Query: 391 ---------QSSPTSKEGGTLPAPVGSPEDPSDPPQPYRLADDYTPAP 429 +SS + G+ PAP S PSDPP + +D TP P Sbjct: 225 PSYNWGAALRSSLVPSDLGSPPAPHASSSPPSDPPL-FHCSDALTPPP 271 Score = 33.1 bits (74), Expect = 3.8 Identities = 29/76 (38%), Positives = 39/76 (51%), Gaps = 8/76 (10%) Query: 1198 LGIEWVGSG-----LNEVPSSLYFLLSPLEGPNLTPEASPDPLPEPPLASVEV-PDKPSG 1251 LG++ + G L+E S L LL L+ P PEA P PE P +++E P +P Sbjct: 773 LGLQLLPGGGAPPPLSEASSPLACLLQSLQIPPEQPEAPCLP-PESPASALEPEPARPPL 831 Query: 1252 SPGQPPSPAPS-PVPE 1266 S PP +P PVPE Sbjct: 832 SALAPPHGSPDPPVPE 847 Score = 32.3 bits (72), Expect = 6.5 Identities = 82/298 (27%), Positives = 98/298 (32%), Gaps = 60/298 (20%) Query: 2332 PPALKAP---PATTPASMPLGAAPTLPRLAPVLLSGPALAQPPLGNLAPFNSGPAASSGL 2388 PP+ + P P TTP + G+ P P V + P LA P G P + P S G Sbjct: 142 PPSARPPCRVPPTTPLNGGPGSLP--PEPPSVSQAFPTLAGPG-GLFPPRLADPVPSGG- 197 Query: 2389 LGLATSVLPTTTVVQTAGPGRPLPQRPMPDQTNTSTAGTTDPVPGPPTEPLGDKVSSERK 2448 + LP A P P P N A + VP P SS Sbjct: 198 -SSSPRFLPRGNAPSPAPPPPPAISLNAPSY-NWGAALRSSLVPSDLGSPPAPHASSS-P 254 Query: 2449 PVAGPTSSSNDAL--------KNLKA---LKTTVPALLGGQFLPFPLPPAGGTAPPAVFG 2497 P P +DAL NL A + P LP L P GG P V G Sbjct: 255 PSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGPLGGA--PTVEG 312 Query: 2498 PQLQGAYFQQLY-GMKKGLFPMNPMIPQTLIGLLPNA---------LLQP----PPQPP- 2542 P L K P P P TL G P A L+P P +PP Sbjct: 313 PGAPPFLASSLLSAAAKAQHPPLPP-PSTLQGRRPRAQAPSASHSSSLRPSQRRPRRPPT 371 Query: 2543 ----------------EPTATAP-PKPPELPAPGEGEAGEVDELLTGSTGISTVDVTH 2583 P A AP P+P LP P + V LL G+ T +H Sbjct: 372 VFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLL----GLPTPGPSH 425 Score = 32.0 bits (71), Expect = 8.5 Identities = 44/164 (26%), Positives = 58/164 (35%), Gaps = 25/164 (15%) Query: 2404 TAGPGRPLPQRPMPDQTNTSTAGTTDPVPGPPTEPLGDKVSSERKPVAGPTSSSNDALKN 2463 T PG P + P T G +P P VS +AGP L + Sbjct: 137 TVSPGPPSARPPCRVPPTTPLNGGPGSLPPEPPS-----VSQAFPTLAGPGGLFPPRLAD 191 Query: 2464 -LKALKTTVPALLGGQFLPFPLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNPMI 2522 + + ++ P L P P PP PPA+ L + ++ L P + Sbjct: 192 PVPSGGSSSPRFLPRGNAPSPAPPP----PPAI---SLNAPSYNWGAALRSSLVPSDLGS 244 Query: 2523 PQTLIGLLPNALLQPPPQPP----EPTATAPPKPP--ELPA-PG 2559 P P+A PP PP T PP PP LPA PG Sbjct: 245 PPA-----PHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPG 283 Score = 32.0 bits (71), Expect = 8.5 Identities = 35/111 (31%), Positives = 43/111 (38%), Gaps = 13/111 (11%) Query: 2053 STPGGVPSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQ 2112 S+PG +PS ++PP L LL G G P EA + P A L Q Sbjct: 753 SSPGALPS-LLQPPGPLLSGQLG-LQLL-----PGGGAPPPLSEASS---PLACLLQSLQ 802 Query: 2113 PFLPPGK-EATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESEACSLSAG 2162 +PP + EA PE P L P P PP SP+ L G Sbjct: 803 --IPPEQPEAPCLPPESPASALEPEPARPPLSALAPPHGSPDPPVPELLTG 851 >gi|153792074 proline rich 12 [Homo sapiens] Length = 2036 Score = 75.5 bits (184), Expect = 7e-13 Identities = 210/816 (25%), Positives = 281/816 (34%), Gaps = 156/816 (19%) Query: 1422 PERSQEEPKEGETEGEVGTEKKGPDTSGFISGLPFLSPPPPPLDLHRFPAPLFTP-PVLP 1480 PE S + P G + +G + P G P S P +R P+P T P Sbjct: 870 PEESLDPP--GAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFV 927 Query: 1481 PFPLV--PESLLKLQQQQLLLPFY-LHDLKVGPKLTLAGPAPVLSLPAATPPPPPQPPKA 1537 P + P+SLL+ +++ + AGP P A PPP PP Sbjct: 928 PLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPPGPPAY 987 Query: 1538 ELAEREWERPPMAKEGNEAGPSSPPDPL-PNEAARTAAKALLENFGFELVIQYNEGKQAV 1596 + P + AGP +P L PN+ + E G +IQ + A Sbjct: 988 DPYG-----PYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLG---LIQSGPHQAAP 1039 Query: 1597 PPPPTPPPPEALGGGDKLACGACGKLFSNML---ILKTHEEHV-HRRFLPFEALSRYAAQ 1652 PPPP PPPP A K G +F + +LKT H+ RR PF+ + AQ Sbjct: 1040 PPPPPPPPPPAPASEPK--GGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPKKLYAQ 1097 Query: 1653 ---FRKSYDSLYPPL---AEPPKPPD-GSLDSPVPHLGP----PFLVPEPEAGGTRAPEE 1701 F D P P + PD S P L P F P P G P Sbjct: 1098 EYEFEADEDKADVPADIRLNPRRLPDLVSSCRSRPALSPLGDIDFCPPNP---GPDGPRR 1154 Query: 1702 RSRAGGHWPIEEEESSRGNLPPLVPAGRRFSRTKFTEFQTQALQSFFETSAYPKDGEVER 1761 R R + ++ + PP P GR R + E T A + T P DG + Sbjct: 1155 RGR--------KPTKAKRDGPPR-PRGR--PRIRPLEVPTTAGPASAST---PTDGAKKP 1200 Query: 1762 LASLLGLASRVVVVWFQNARQKARKNACEGGSMPTGG-GTGGASGCRRCHATFSCVFELV 1820 G + R + K S+P G G G +SG + + Sbjct: 1201 RGRGRGRGRKAEEAG--GTRLEPLKPLKIKLSVPKAGEGLGTSSGDAISGTDHNSL---- 1254 Query: 1821 RHLKKCYDDQTLEEEEEEAERGEEEEEVEEEEVEEEQGLEPPAGPEGPLPEPPDGEELSQ 1880 D +L E+ EA+ +EVEE+Q PE G S Sbjct: 1255 --------DSSLTREKIEAKI---------KEVEEKQ------------PEMKSGFMASF 1285 Query: 1881 AEATKAGGKEP---EEKATPSPSPAHTCDQCAISFSSQDLLTSHRRLHFLPSLQPSAPPQ 1937 + K+G + P + TP SP S+ PS P + Sbjct: 1286 LDFLKSGKRHPPLYQAGLTPPLSPPK-------------------------SVPPSVPAR 1320 Query: 1938 LLDLPLLVFGERNPLVAATSPMPGPPLKRKHEDGSLSPTGSEAGGGGEGEPPRDKRLRTT 1997 L P AT +P PP G + +E+ G G G P KRL Sbjct: 1321 GLQ----------PQPPATPAVPHPPPSGAFGLGG-ALEAAESEGLGLGCPSPCKRLDEE 1369 Query: 1998 ILPEQLEILYRWYMQDSNPTRKMLDC---ISEEVGLKKRVVQVWFQNTRARERKGQFRST 2054 L LE L + + + K D IS + ++T ST Sbjct: 1370 -LKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDT----------ST 1418 Query: 2055 PGGVP-SPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGP-- 2111 P G P +PA P LP N G + E P P P P P Sbjct: 1419 PDGPPLAPAAAVPGPPPLPGLPSANSN-GTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPP 1477 Query: 2112 -QPFLP--PGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPK-----ASPESEACSLSAGD 2163 QP LP P A TP+ PP PL PPPPP+ P PP A+P E + S D Sbjct: 1478 PQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPED 1537 Query: 2164 --LSDSSASSLAEPESPGA--GGT--SGGPGGGTGV 2193 L D+ LA+ + A G T G GG G+ Sbjct: 1538 PELPDTRPLHLAKKQETAAVCGETDEEAGESGGEGI 1573 Score = 44.7 bits (104), Expect = 0.001 Identities = 166/778 (21%), Positives = 238/778 (30%), Gaps = 194/778 (24%) Query: 1883 ATKAGGKEPEEKATPSPSPAHTCDQCAISFSSQDLLTSHRRLHFLPSLQPSA---PPQLL 1939 AT+ G +P P P P L +H R H L PS P + L Sbjct: 827 ATRDGAPQPPPPPPPPPPPMPL------------QLEAHLRSHGLEPAAPSPRLRPEESL 874 Query: 1940 DLPLLVFGERNPLVAATSPMP--------GPPLKRKHEDGSLSPTGSEAGGGGEG-EPPR 1990 D P G L+ A P+P GPP + +G P G+ +G + PR Sbjct: 875 DPP----GAMQELLGALEPLPPAPGDTGVGPP----NSEGK-DPAGAYRSPSPQGTKAPR 925 Query: 1991 DKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQNTRARERKGQ 2050 L + P+ L +QD R + E G + E +G Sbjct: 926 FVPLTSICFPDSL-------LQDEE--RSFFPTMEEMFG---GGAADDYGKAGPPEDEGD 973 Query: 2051 FRSTPGGVPSPAVKPPATATPASLPKFNLLLGKVDDGTGREAP-----KREAPAFPY--- 2102 ++ G P P PA P G+ G G E P + P P Sbjct: 974 PKAGAGPPPGP---------PAYDPYGPYCPGRAS-GAGPETPGLGLDPNKPPELPSTVN 1023 Query: 2103 --PTATLASGPQPFLPPGKEATTPTPEPPLPLLPPP------------------------ 2136 P + SGP PP P P PP P P Sbjct: 1024 AEPLGLIQSGPHQAAPP---PPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHL 1080 Query: 2137 -----PP---------------SEEEGPEEP------PKASPESEACSLSAGDLSDSSAS 2170 PP ++E+ + P P+ P+ + S LS Sbjct: 1081 LRRRDPPFQTPKKLYAQEYEFEADEDKADVPADIRLNPRRLPDLVSSCRSRPALSPLGDI 1140 Query: 2171 SLAEPESPGAGGTSGGPGGGTGVPDGMGQRRYRTQMSSLQLKIMKACYEAYRTPTMQECE 2230 P G G DG + R R ++ L++ A TPT + Sbjct: 1141 DFCPPNPGPDGPRRRGRKPTKAKRDGPPRPRGRPRIRPLEVPTTAGPASA-STPTDGAKK 1199 Query: 2231 VLGEEIGLPKRVIQVWFQNARA-KEKKAKLQGTAAGSTGGSSEGLLAAQRTDCPYCDVKY 2289 G G ++ + K K KL AG G+S G A TD Sbjct: 1200 PRGRGRGRGRKAEEAGGTRLEPLKPLKIKLSVPKAGEGLGTSSGD-AISGTD-------- 1250 Query: 2290 DFYVSCRGHLFSRQHLAKLKEAVRAQLKSES----KCYDLAPAPEAPPALKAPPATTPAS 2345 + S L + AK+KE Q + +S D + + P L T P S Sbjct: 1251 --HNSLDSSLTREKIEAKIKEVEEKQPEMKSGFMASFLDFLKSGKRHPPLYQAGLTPPLS 1308 Query: 2346 MPLGAAPTLPR--LAPVLLSGPALAQPPLGNLAPFNSGPAASSGLLGLATSVLPTTTVVQ 2403 P P++P L P + PA+ PP P+ + GL G + + Sbjct: 1309 PPKSVPPSVPARGLQPQPPATPAVPHPP----------PSGAFGLGGALEAAESEGLGLG 1358 Query: 2404 TAGPGRPLPQRPMPDQTNTSTAGTTDPVPGPPTEPLGDKVSS-----ERKPVAGPTSSSN 2458 P + L + + + + + L + +SS + P+AGP +S Sbjct: 1359 CPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTST 1418 Query: 2459 D------------------ALKNLKALKTTVPALLGGQFLPFPLPPAGGTAPPAVFGPQL 2500 L + + T P LL + P P PP T P P Sbjct: 1419 PDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEK--PPPTPPPAPTPQPQPPPPPP 1476 Query: 2501 QGAYFQQLYGMKKGLFPMNPMIPQTLIGLLPNALLQPPPQPPEPTATAPPKPPELPAP 2558 P P +P P L+ P P P P PP PP +P+P Sbjct: 1477 ----------------PPQPALPS------PPPLVAPTPSSPPPPPLPPPPPPAMPSP 1512 Score = 44.3 bits (103), Expect = 0.002 Identities = 28/87 (32%), Positives = 33/87 (37%), Gaps = 2/87 (2%) Query: 1220 PLEGPNLTPEASPDPLPEPPLASVEVPDKPSGSPGQPPSPAPSPVPEPDAQAEDVAPPPT 1279 P P TP+ P P P PP ++ P P P SP P P+P P A PPP Sbjct: 1459 PTPPPAPTPQPQPPPPPPPPQPAL--PSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPP 1516 Query: 1280 MAEEEEGTTGELRSAEPAPADSRHPLT 1306 A P+P D P T Sbjct: 1517 PPAAAPLAAPPEEPAAPSPEDPELPDT 1543 Score = 41.2 bits (95), Expect = 0.014 Identities = 50/173 (28%), Positives = 62/173 (35%), Gaps = 41/173 (23%) Query: 1469 FPAP----LFTPPVLPPFP--LVPESLLKLQQQQL-LLPFYL--HDLKVGPKLTLAGPAP 1519 FP P L PP PP L P +L L+ Q +P L L G L AG P Sbjct: 162 FPVPSSLSLQDPPFSPPANGLLSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPAGLGP 221 Query: 1520 VLSLPAATPPPPPQPPKAEL--------------AEREWERPPMAK-EGNEAGPSSPPDP 1564 + P PP P PP L A E P + G GP P Sbjct: 222 AQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPERA 281 Query: 1565 LPNEAARTAAKALLENFGFELVIQYNEGKQAVPPPPTPPPPEALGGGDKLACG 1617 LP + + VI++ + + PPP PPP AL L+CG Sbjct: 282 LPRQ---------------DTVIKHYQRPASAQPPPPPPPAHAL--QHYLSCG 317 Score = 40.8 bits (94), Expect = 0.018 Identities = 97/389 (24%), Positives = 127/389 (32%), Gaps = 73/389 (18%) Query: 1366 GEAGAPPTTT--AATDKPFKCTVCRVSYNQSSTLEIHMRSVLHQTRSRGTKTDSKIEGPE 1423 G AG PP T A + P + + V S++L+ + L R K +GPE Sbjct: 678 GGAGGPPGTPYELAKEDPQRYHLQSV-IRTSASLDEGATAALELGLGR---LKEKKKGPE 733 Query: 1424 RSQEEPKEGETEGEVGTEKKGPDTSGFISGLPFLSPPPPPLDLHRFPAP--LFTPPVLPP 1481 R E P EG V + F+ P PPPPP P P L P Sbjct: 734 RGGETP-EGLATSVVHYGAGAKELGAFLQKSP---PPPPPTAQSTQPTPHGLLLEAGGPD 789 Query: 1482 FPLVPESLLKLQQQQLLLPFYLHDLKVGPKLTLAG------------PAPVLSLPAATPP 1529 PLV L QLL H P + G P P P PP Sbjct: 790 LPLV----LPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPP---PPPPPP 842 Query: 1530 PPPQPPKAELAEREWERPPMAKEGNEAGPSSPPDPLPNEAARTAAKALLENFGFELVIQY 1589 PPP P + E R G E P++P L E + A+ E G Sbjct: 843 PPPMPLQLEAHLR--------SHGLE--PAAPSPRLRPEESLDPPGAMQELLG------- 885 Query: 1590 NEGKQAVPPPPTPPPPEALGGGDKLACGACGKLFSNMLILKTHEEHVHRRFLPFEALSRY 1649 P PP P G G + GK + + + RF+P ++ Sbjct: 886 -------ALEPLPPAPGDTGVGPP---NSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFP 935 Query: 1650 AAQFRKSYDSLYPPLAE-----------PPKPPDGSLDSPVPHLGPPFLVPEPEAGGTRA 1698 + + S +P + E PP+ D P GPP P P A Sbjct: 936 DSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGD-PKAGAGPP---PGPPAYDPYG 991 Query: 1699 PEERSRAGGHWPIEEEESSRGNLPPLVPA 1727 P RA G P N PP +P+ Sbjct: 992 PYCPGRASGAGPETPGLGLDPNKPPELPS 1020 Score = 40.4 bits (93), Expect = 0.024 Identities = 48/176 (27%), Positives = 56/176 (31%), Gaps = 31/176 (17%) Query: 1403 SVLHQTRSRGTKTDSKIEGPERSQEEPKEGETE--GEVGTEKKGPDTSGFISGLPFLSPP 1460 S L G K S +GP + G G G + P +PP Sbjct: 1403 SALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPP 1462 Query: 1461 PPPLDLHRFPAPLFTPPVLPPFPLVPESLLKLQQQQLLLPFYLHDLKVGPKLTLAGPAPV 1520 P P P P PP PP P +P L+ P P P P Sbjct: 1463 PAPT-----PQPQPPPPPPPPQPALPSP------PPLVAPT--------PSSPPPPPLPP 1503 Query: 1521 LSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPSSPPDP-LPNEAARTAAK 1575 PA PPPP PP A P+A E SP DP LP+ AK Sbjct: 1504 PPPPAMPSPPPPPPPAA---------APLAAPPEEPAAPSPEDPELPDTRPLHLAK 1550 Score = 39.7 bits (91), Expect = 0.041 Identities = 26/80 (32%), Positives = 32/80 (40%), Gaps = 6/80 (7%) Query: 1220 PLEGPNLTPEASPDPLPEPPLASVEVPDKPSGSPGQPPSPAPSPVPEPDAQAEDVAPPPT 1279 PL G P A+ + PEPPL + P P +P P P P P P A +PPP Sbjct: 1435 PLPG---LPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALP---SPPPL 1488 Query: 1280 MAEEEEGTTGELRSAEPAPA 1299 +A P PA Sbjct: 1489 VAPTPSSPPPPPLPPPPPPA 1508 Score = 38.9 bits (89), Expect = 0.070 Identities = 53/182 (29%), Positives = 67/182 (36%), Gaps = 22/182 (12%) Query: 2054 TPGGVPSPAVKPPATATPASLP-KFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQ 2112 TP P P PP P LP +FNLL A ++ +P Y + A GP Sbjct: 224 TPPYRPGPPDPPPP---PRHLPTQFNLL---ASSSAAAAAAEQSSPQL-YNFSGAAPGPP 276 Query: 2113 P--FLPPGKEATTPTPEPPLPLLPPPPPSEEE--------GPEEPPKASPESEACS-LSA 2161 P P ++ + P PPPPP G P + ACS L Sbjct: 277 PPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGG 336 Query: 2162 GDLSDSSAS-SLAEPE--SPGAGGTSGGPGGGTGVPDGMGQRRYRTQMSSLQLKIMKACY 2218 G+ S + S A P + GA G + GP G G G YR + S K K Y Sbjct: 337 GEPSPGAGEPSKAGPSGATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGY 396 Query: 2219 EA 2220 A Sbjct: 397 GA 398 Score = 38.9 bits (89), Expect = 0.070 Identities = 69/267 (25%), Positives = 90/267 (33%), Gaps = 67/267 (25%) Query: 1969 EDGSLSPTGSEAGGGGEGEPPRDKRLRTTILPEQL--EILYRWYMQDSNPTRKMLD---C 2023 EDG+ + G GG G PP P +L E R+++Q T LD Sbjct: 664 EDGAADASKGLGGSGGAGGPPGT--------PYELAKEDPQRYHLQSVIRTSASLDEGAT 715 Query: 2024 ISEEVGLKKRVVQVWFQNTRARERKGQFRSTPGGVPSPAVK------------------P 2065 + E+GL + + + ER G+ TP G+ + V P Sbjct: 716 AALELGLGRLK-----EKKKGPERGGE---TPEGLATSVVHYGAGAKELGAFLQKSPPPP 767 Query: 2066 PATATPASLPKFNLLLGKVDDGTGREAPKREAPAFPYPT-ATLASGPQP----------F 2114 P TA LLL + G + P P P + L+ P P Sbjct: 768 PPTAQSTQPTPHGLLL----EAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHL 823 Query: 2115 LPPGKEATTPTPEPPLPLLPPPPPSEEEG--------PEEP-PKASPESEACSLSAGDLS 2165 L P P P PP P PPP P + E P P P+ PE SL Sbjct: 824 LEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEE---SLDPPGAM 880 Query: 2166 DSSASSLAEPESPGAGGTSGGPGGGTG 2192 +L EP P G T GP G Sbjct: 881 QELLGAL-EPLPPAPGDTGVGPPNSEG 906 Score = 38.9 bits (89), Expect = 0.070 Identities = 33/106 (31%), Positives = 39/106 (36%), Gaps = 21/106 (19%) Query: 1217 LLSPLEGPNLTPEA-SPDPLPEPPLASVEV----PDKPSGSPGQPPSPAPSPVPEP---- 1267 L+ P P L P S P P P + V V P G+P PP P P P P P Sbjct: 792 LVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLE 851 Query: 1268 ----DAQAEDVAPPPTMAEEE--------EGTTGELRSAEPAPADS 1301 E AP P + EE + G L PAP D+ Sbjct: 852 AHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDT 897 Score = 37.4 bits (85), Expect = 0.20 Identities = 28/75 (37%), Positives = 33/75 (44%), Gaps = 15/75 (20%) Query: 1220 PLEGPNLTPEASPDPLPEPPLASV----EVPDKPS----GSPGQP-----PSPAPSPVPE 1266 PL GP T ++PD P P A+V +P PS G+P P P P P P P Sbjct: 1409 PLAGPKDT--STPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPT 1466 Query: 1267 PDAQAEDVAPPPTMA 1281 P Q PPP A Sbjct: 1467 PQPQPPPPPPPPQPA 1481 Score = 37.0 bits (84), Expect = 0.26 Identities = 74/338 (21%), Positives = 110/338 (32%), Gaps = 58/338 (17%) Query: 2327 PAPEA-PPALKAPPATTPASMPLGA---APTLPRLAPVLLSGPALAQPPL-----GNLAP 2377 P P+ P L P+ +P++ +G P AP P PP+ +L Sbjct: 797 PPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRS 856 Query: 2378 FNSGPAASSGLLGLATSVLPTTTVVQTAGPGRPLPQRPMPDQTNTSTAGTTDPVPGPPTE 2437 PAA S L S+ P + + G PLP P P T GPP Sbjct: 857 HGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLP--PAPGDTGV----------GPPNS 904 Query: 2438 PLGDKVSSERKPVAGPTSSSN----------DAL--KNLKALKTTVPALLGG----QFLP 2481 D + R P T + D+L ++ T+ + GG + Sbjct: 905 EGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGK 964 Query: 2482 FPLP-----PAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNP----------MIPQTL 2526 P P G PP GP Y G G P P +P T Sbjct: 965 AGPPEDEGDPKAGAGPPP--GPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPST- 1021 Query: 2527 IGLLPNALLQPPPQPPEPTATAPPKPPELPAPGEGEAGEVDELLTGSTGISTVDVTHRYL 2586 + P L+Q P P PP PP PA E + G + + + + +L Sbjct: 1022 VNAEPLGLIQSGPHQAAPPPPPPPPPPPAPA-SEPKGGLTSPIFCSTKPKKLLKTSSFHL 1080 Query: 2587 CRQCKMAFDGEAPATAHQRSFCFFGRGSGGSMPPPLRV 2624 R+ F + P + + + F +P +R+ Sbjct: 1081 LRRRDPPF--QTPKKLYAQEYEFEADEDKADVPADIRL 1116 Score = 35.8 bits (81), Expect = 0.59 Identities = 20/67 (29%), Positives = 28/67 (41%), Gaps = 3/67 (4%) Query: 1235 LPEPPLASVEVPDKPSGSPGQPPSPAPSPVP---EPDAQAEDVAPPPTMAEEEEGTTGEL 1291 L +PPLA + P G P P + P P P P A + PP + E+ T Sbjct: 1405 LDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPA 1464 Query: 1292 RSAEPAP 1298 + +P P Sbjct: 1465 PTPQPQP 1471 Score = 35.0 bits (79), Expect = 1.0 Identities = 60/226 (26%), Positives = 73/226 (32%), Gaps = 21/226 (9%) Query: 2348 LGAAPTLPRLAPVLLSGPALAQPPLGNLAPFNSGPAASSGLLGLATSVLPTTTVVQTAGP 2407 LG A P P GP PP +L + A+SS A P A P Sbjct: 214 LGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAP 273 Query: 2408 GRPLPQRPMPDQTNT-----STAGTTDPVPGPPTEPLGDKVSSERKPVAGPTSSSNDALK 2462 G P P+R +P Q A P P PP L +S G + S Sbjct: 274 GPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLS------CGGSYPSMGHRA 327 Query: 2463 NLKALKTTVPALLGGQFLPFPLPPAGGTAPPA--VFGPQLQGAYFQQLYGMKKGLFPMNP 2520 NL G P P+G TA + GP+ G G G P Sbjct: 328 NLACSPLGGGEPSPGAGEPSKAGPSGATAGASGRATGPEAAGG-----GGAGGGGGGYRP 382 Query: 2521 MI--PQTLIGLLP-NALLQPPPQPPEPTATAPPKPPELPAPGEGEA 2563 +I P G A +PP P +TA PK L P A Sbjct: 383 IIQSPGYKTGKGGYGAAAGGATRPPPPRSTATPKCQSLGGPAAAYA 428 Score = 33.9 bits (76), Expect = 2.2 Identities = 15/28 (53%), Positives = 17/28 (60%), Gaps = 1/28 (3%) Query: 604 LPLGLPPGLMGPGPPPPPGATP-TSPPE 630 LP PP + P PPPPP A P +PPE Sbjct: 1501 LPPPPPPAMPSPPPPPPPAAAPLAAPPE 1528 Score = 33.5 bits (75), Expect = 2.9 Identities = 32/115 (27%), Positives = 41/115 (35%), Gaps = 11/115 (9%) Query: 608 LPPGLMGPGPPPPPG-----ATPTSPPELFQYFGPQA-----LGQPQTPLAGPGLRPDKP 657 L P PGPPP PG + T P L + P QPQ P P +P P Sbjct: 1424 LAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALP 1483 Query: 658 LEAQLLLNGFHHVGAPARKFPTSAPGSLSPDAHLPPSQLLGSSSDSLPTSPPPDD 712 L+ P P P SP PP+ ++ P +P P+D Sbjct: 1484 SPPPLVAPTPSSPPPPPLP-PPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPED 1537 Score = 32.0 bits (71), Expect = 8.5 Identities = 22/58 (37%), Positives = 24/58 (41%), Gaps = 8/58 (13%) Query: 2325 LAPAPEAPPALKAPPATTPASMPLGAAPTLPRLAPVLLSGPALAQPPLGNLAPFNSGP 2382 +AP P +PP PP PA MP P P AP LA PP AP P Sbjct: 1489 VAPTPSSPPPPPLPPPPPPA-MPSPPPPPPPAAAP-------LAAPPEEPAAPSPEDP 1538 Score = 32.0 bits (71), Expect = 8.5 Identities = 21/72 (29%), Positives = 32/72 (44%), Gaps = 10/72 (13%) Query: 1224 PNLTPEASPDPLPEPPLASVEVPDKPSGSPGQPPSPAPSPVPEPD------AQAEDVAPP 1277 P P A P P P PP A+ + + P +P +P+P PD A+ ++ A Sbjct: 1502 PPPPPPAMPSPPPPPPPAAAPL----AAPPEEPAAPSPEDPELPDTRPLHLAKKQETAAV 1557 Query: 1278 PTMAEEEEGTTG 1289 +EE G +G Sbjct: 1558 CGETDEEAGESG 1569 >gi|50083287 LIM homeobox 8 [Homo sapiens] Length = 356 Score = 73.2 bits (178), Expect = 3e-12 Identities = 52/154 (33%), Positives = 74/154 (48%), Gaps = 6/154 (3%) Query: 1964 LKRKHEDGS-LSPTGSEAGGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLD 2022 LKR+ E+G+ +S G+ P KR RT+ +QL+++ + QD+NP + L Sbjct: 197 LKREVENGNGISVEGALLTEQDVNHPKPAKRARTSFTADQLQVMQAQFAQDNNPDAQTLQ 256 Query: 2023 CISEEVGLKKRVVQVWFQNTRARERKGQFRSTPGGVPSPAVKPPATATPASLPKFNLLLG 2082 ++E GL +RV+QVWFQN RAR +K + P AV PP+ +P L + Sbjct: 257 KLAERTGLSRRVIQVWFQNCRARHKKHVSPNHSSSTPVTAV-PPSRLSPPMLEEMAYSAY 315 Query: 2083 KVDDGTGREAPKREAPAFPYPTATLASGPQPFLP 2116 DGT A A T G QP LP Sbjct: 316 VPQDGTMLTALHSYMDAHSPTTL----GLQPLLP 345 Score = 54.3 bits (129), Expect = 2e-06 Identities = 26/57 (45%), Positives = 36/57 (63%) Query: 2200 RRYRTQMSSLQLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKK 2256 +R RT ++ QL++M+A + P Q + L E GL +RVIQVWFQN RA+ KK Sbjct: 226 KRARTSFTADQLQVMQAQFAQDNNPDAQTLQKLAERTGLSRRVIQVWFQNCRARHKK 282 Score = 47.8 bits (112), Expect = 1e-04 Identities = 25/71 (35%), Positives = 37/71 (52%) Query: 1726 PAGRRFSRTKFTEFQTQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKAR 1785 P + +RT FT Q Q +Q+ F P +++LA GL+ RV+ VWFQN R + + Sbjct: 222 PKPAKRARTSFTADQLQVMQAQFAQDNNPDAQTLQKLAERTGLSRRVIQVWFQNCRARHK 281 Query: 1786 KNACEGGSMPT 1796 K+ S T Sbjct: 282 KHVSPNHSSST 292 >gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Homo sapiens] Length = 406 Score = 72.8 bits (177), Expect = 4e-12 Identities = 77/308 (25%), Positives = 113/308 (36%), Gaps = 24/308 (7%) Query: 2141 EEGPEEPPKASPESEACSLSAGDLSDSSASSLAEPESPGAGGT--SGGPGGGTGVPDGMG 2198 E+ EEPP PE + +L EP G + GP G Sbjct: 83 EQQQEEPPLTKPEQQQEEPPLLELKQEQE----EPPQTTVEGPQPAEGPQTAEGPQPPER 138 Query: 2199 QRRYRTQMSSLQLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAK 2258 +RR RT + QL+ ++ ++ + P + E L + L + +QVWFQN RAK K+ + Sbjct: 139 KRRRRTAFTQFQLQELENFFDESQYPDVVARERLAARLNLTEDRVQVWFQNRRAKWKRNQ 198 Query: 2259 ----LQGTAAGSTGGSSEGLLAAQRTDCPYCDVKYDFYVSCRGHLFSRQHLAKLKEAVRA 2314 L+ TA + L P D ++ + +L Sbjct: 199 RVLMLRNTATADLAHPLDMFLGGAYYAAPALDPALCVHL-----------VPQLPRPPVL 247 Query: 2315 QLKSESKCYDLAPAPEAPPALKAPP-ATTPASMPLGAAPTLPRLAPVLLSGPALAQPPLG 2373 + + P P PP PP A P + P PR+APV P PP Sbjct: 248 PVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPWP 307 Query: 2374 NLAPFNSGPAASSGLLGLATSVLPTTTVVQTAGPGRPL-PQRPMPDQTNTSTAGTTDPV- 2431 +AP +GP + G + +P + PG P+ P P P P+ Sbjct: 308 PMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLPPGPPMAPLPPGPPMAPLP 367 Query: 2432 PGPPTEPL 2439 PGPP PL Sbjct: 368 PGPPMAPL 375 Score = 62.0 bits (149), Expect = 8e-09 Identities = 43/126 (34%), Positives = 61/126 (48%), Gaps = 17/126 (13%) Query: 1662 PPLAEPPKPPDGSLDSPVPHLGPPFLVPEPEAGGTRAPEERSRAGGHWPIEEEESSRGNL 1721 PPL +P + + PP L + E + ++ G P E +++ G Sbjct: 89 PPLTKPEQQQEE----------PPLLELKQE----QEEPPQTTVEGPQPAEGPQTAEGPQ 134 Query: 1722 PPLVPAGRRFSRTKFTEFQTQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNAR 1781 PP +R RT FT+FQ Q L++FF+ S YP ERLA+ L L V VWFQN R Sbjct: 135 PP---ERKRRRRTAFTQFQLQELENFFDESQYPDVVARERLAARLNLTEDRVQVWFQNRR 191 Query: 1782 QKARKN 1787 K ++N Sbjct: 192 AKWKRN 197 Score = 56.2 bits (134), Expect = 4e-07 Identities = 79/320 (24%), Positives = 106/320 (33%), Gaps = 73/320 (22%) Query: 1841 RGEEEEEVEEEEVEEEQGLEPPAGPEGPLPEPPDGEELSQAEATKAGGKEPEEKATPSPS 1900 RG E+EE + E E G EG +P E GG EPE++ P Sbjct: 39 RGGEDEENTRSKPEYGTEAENNVGTEGSVPSDDQDRE-------GGGGHEPEQQQEEPP- 90 Query: 1901 PAHTCDQCAISFSSQDLLTSHRRLHFLPSLQPSAPPQLLDLPLLVFGERNPLVAATSPMP 1960 LT P Q PP L L E P P P Sbjct: 91 -----------------LTK-------PEQQQEEPPLL---ELKQEQEEPPQTTVEGPQP 123 Query: 1961 GPPLKRKHEDGSLSPTGSEAGGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKM 2020 P +E G P R +R RT QL+ L ++ + P Sbjct: 124 AE-----------GPQTAE----GPQPPERKRRRRTAFTQFQLQELENFFDESQYPDVVA 168 Query: 2021 LDCISEEVGLKKRVVQVWFQNTRARERKGQFRSTPGGVPSPAVKPPATATPASLPKFNLL 2080 + ++ + L + VQVWFQN RA+ ++ Q + TAT ++ Sbjct: 169 RERLAARLNLTEDRVQVWFQNRRAKWKRNQ----------RVLMLRNTATADLAHPLDMF 218 Query: 2081 LGKVDDGTGREAPKRE-------APAFPYPTATLASGPQPFLPPGKEATTPTPEPPLPLL 2133 LG G AP + P P P L P P PP P P+P + Sbjct: 219 LG----GAYYAAPALDPALCVHLVPQLPRP-PVLPVPPMPPRPPMVPMPPRPPIAPMPPM 273 Query: 2134 PPPPPSEEEGPEEP-PKASP 2152 P PP P P P+ +P Sbjct: 274 APVPPGSRMAPVPPGPRMAP 293 Score = 33.5 bits (75), Expect = 2.9 Identities = 38/141 (26%), Positives = 56/141 (39%), Gaps = 33/141 (23%) Query: 1450 FISGLPFLSPP-PPPLDLHRFPAPLFTPPVLPPFPLVPE-SLLKLQQQQLLLPF------ 1501 F+ G + +P P L +H P L PPVLP P+ P ++ + + + P Sbjct: 218 FLGGAYYAAPALDPALCVHLVPQ-LPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPV 276 Query: 1502 ----YLHDLKVGPKLTLAGPAPVLS--------LPAATPPP----PPQPPKAELAEREWE 1545 + + GP++ P P ++ P T PP PP PP A + Sbjct: 277 PPGSRMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVP----P 332 Query: 1546 RPPMAKEGNEAGPSSPPDPLP 1566 PPMA+ P P PLP Sbjct: 333 GPPMAR----VPPGPPMAPLP 349 Score = 32.0 bits (71), Expect = 8.5 Identities = 20/48 (41%), Positives = 22/48 (45%), Gaps = 6/48 (12%) Query: 2517 PMNPMIPQTLIGLLPNALLQPP-----PQPPEPT-ATAPPKPPELPAP 2558 PM PM P+ I +P PP P PP P A PP PP P P Sbjct: 257 PMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWPPMAPVP 304 >gi|152963644 paired-like homeodomain transcription factor 1 [Homo sapiens] Length = 314 Score = 70.1 bits (170), Expect = 3e-11 Identities = 69/242 (28%), Positives = 104/242 (42%), Gaps = 32/242 (13%) Query: 2129 PLPLLPPPPPSEEEGPE------EPPKASPESEACSLSAGDLSDSSASSLAE-PESPGAG 2181 P L PPPPP + GP P+ E+ A S +L + + PE GAG Sbjct: 14 PEGLRPPPPPPHDMGPAFHLARPADPREPLENSASESSDTELPEKERGGEPKGPEDSGAG 73 Query: 2182 GTSGGPGGGTGVPDGMGQRRYRTQMSSLQLKIMKACYEAYRTPTMQECEVLGEEIGLPKR 2241 GT G GG QRR RT +S QL+ ++A ++ R P M E + L + Sbjct: 74 GT--GCGGADDPAKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEP 131 Query: 2242 VIQVWFQNARAKEKKAKLQGTAAGSTGG---SSEGLLAAQRTDCPYCDVKYDFYVSCRGH 2298 ++VWF+N RAK +K + GG GL+ PY D V G+ Sbjct: 132 RVRVWFKNRRAKWRKRERNQQLDLCKGGYVPQFSGLVQ------PYED------VYAAGY 179 Query: 2299 LFSRQHLAKLKEAVRAQLKSESKCYDLAPAPEAPPALKAPPA-----TTPASMPLGAAPT 2353 ++ K A L ++S + + +P + ++ + P+ T P+SM GA P Sbjct: 180 SYNNW---AAKSLAPAPLSTKSFTFFNSMSPLSSQSMFSAPSSISSMTMPSSMGPGAVPG 236 Query: 2354 LP 2355 +P Sbjct: 237 MP 238 Score = 55.5 bits (132), Expect = 7e-07 Identities = 49/157 (31%), Positives = 63/157 (40%), Gaps = 23/157 (14%) Query: 1662 PPLAEPPKPPDGSLDSPVPHLGPPFLVPEP------EAGGTRAPEERSRAGGHWPIEEEE 1715 P PP PP + P HL P EP E+ T PE+ G P E+ Sbjct: 14 PEGLRPPPPPPHDM-GPAFHLARPADPREPLENSASESSDTELPEKER---GGEPKGPED 69 Query: 1716 SSRGNL------PPLVPAGRRFSRTKFTEFQTQALQSFFETSAYPKDGEVERLASLLGLA 1769 S G P +R RT FT Q Q L++ F+ + YP E +A L Sbjct: 70 SGAGGTGCGGADDPAKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLT 129 Query: 1770 SRVVVVWFQNARQKARK-------NACEGGSMPTGGG 1799 V VWF+N R K RK + C+GG +P G Sbjct: 130 EPRVRVWFKNRRAKWRKRERNQQLDLCKGGYVPQFSG 166 Score = 44.7 bits (104), Expect = 0.001 Identities = 35/107 (32%), Positives = 49/107 (45%), Gaps = 7/107 (6%) Query: 1949 RNPLVAATSPMPGPPLKRKHEDGS-LSPTGSEAGG---GGEGEPPRDK---RLRTTILPE 2001 R PL + S L K G P S AGG GG +P + K R RT + Sbjct: 40 REPLENSASESSDTELPEKERGGEPKGPEDSGAGGTGCGGADDPAKKKKQRRQRTHFTSQ 99 Query: 2002 QLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQNTRARERK 2048 QL+ L + ++ P M + I+ L + V+VWF+N RA+ RK Sbjct: 100 QLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRK 146 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 69.3 bits (168), Expect = 5e-11 Identities = 86/281 (30%), Positives = 105/281 (37%), Gaps = 44/281 (15%) Query: 2327 PAPEAPPALKAPPATTPASMPLGAAPTLPRLAPVLLSGPAL-------AQPPLGNLA-PF 2378 P P+APPAL +PP S PL T P AP L+ P L A PPL LA P Sbjct: 590 PPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPS 649 Query: 2379 NSGPAASSGLLGLATSVLPTTTVVQT--AGPGRP--LPQRPMPDQTNTSTAGTTDPVP-- 2432 P A + L A P + VQ + P P P P Q S A VP Sbjct: 650 PQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPS 709 Query: 2433 ---GPPTEPLGDKVSSERKPVAG------PTSSSNDALKNLKALKTTVPALLGGQFLPF- 2482 PP P P+A P+ ++ + VP LL L Sbjct: 710 PPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVP 769 Query: 2483 PLPPAG----------GTAPPAVFGPQLQ------GAYFQQLYGMKKGLFPMNPMI--PQ 2524 P PPA APPA+ P LQ ++ Q PM+P+ P Sbjct: 770 PSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPP 829 Query: 2525 TLIGLLPNALLQPPPQPP-EPTATAPPKPPELPAPGEGEAG 2564 +L LLQ PP PP PT AP +PP P P +G Sbjct: 830 QAPPVLAAPLLQVPPSPPASPTLQAPRRPP-TPGPDTSVSG 869 Score = 62.4 bits (150), Expect = 6e-09 Identities = 74/267 (27%), Positives = 103/267 (38%), Gaps = 46/267 (17%) Query: 2327 PAPEAPPALK---APPATTPASMP-------LGAAPTLPRLAPVL----LSGPALAQPPL 2372 P+P APP+L+ +PPAT P+ P + A P+L + P+ L+ P+L PP Sbjct: 346 PSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPP- 404 Query: 2373 GNLAPFNSGPAASSGL---LGLATSVLPTTTVVQTAGPGRPLPQRPMPDQTNTSTAGTTD 2429 P A S L L + L T T P + P + ST + Sbjct: 405 --------SPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRP-ASTPPDSP 455 Query: 2430 PVPGPPTEPLGDKVSSERKPVAGPTSS--SNDALKNLKALKTTVP-ALLGGQFLPFPL-- 2484 P+ P + P + + P P SS + L+ L +L + P A L +P PL Sbjct: 456 PLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMP-PLET 514 Query: 2485 -----------PPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNPMIPQTL-IGLLPN 2532 PPA T PP P L Q P P + P+ Sbjct: 515 QSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPS 574 Query: 2533 ALLQPPPQPPEPTATAPPK-PPELPAP 2558 L PPP+ P AT PP+ PP L +P Sbjct: 575 PLTTPPPETPSSIATPPPQAPPALASP 601 Score = 56.6 bits (135), Expect = 3e-07 Identities = 72/245 (29%), Positives = 94/245 (38%), Gaps = 26/245 (10%) Query: 2326 APAP-EAPPA-LKAPPATTPASMPLGAAPTLPRLAPVLLSGPALAQPPLGNLAPFNSGPA 2383 AP P +APP+ L PP TP+S+ T P AP L+ P L P L+P + P Sbjct: 565 APCPLQAPPSPLTTPPPETPSSI-----ATPPPQAPPALASPPLQGLPSPPLSPLATPPP 619 Query: 2384 ASSGLLGLATSVLPTTTVVQTAGPGRPLPQRPMPDQTNTSTAGTTD-PVPGPPTEPLGDK 2442 + L L P + + P PL P P N P PP+ P+ Sbjct: 620 QAPPXLALPPLQAPPSP--PASPPLSPL-ATPSPQAPNALAVHLLQAPFSPPPSPPVQAP 676 Query: 2443 VSSERKPVAGPTSS-SNDALKNLKALKTTVPALLGGQFLPFPLPPAGGTAPPAVFGPQLQ 2501 S P P+++ + A +L A VP P PP +A P P Sbjct: 677 FSPPASPPVSPSATPPSQAPPSLAAPPLQVPP------SPPASPPMSPSATPPPQAPPPL 730 Query: 2502 GAYFQQLYGMKKGLFPMNPMI--PQTLIGLLPNALLQPPPQPP-----EPTATAPPK-PP 2553 A Q+ PM+P P + LL LQ PP PP P A PP+ PP Sbjct: 731 AAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPP 790 Query: 2554 ELPAP 2558 L P Sbjct: 791 ALATP 795 Score = 55.5 bits (132), Expect = 7e-07 Identities = 117/491 (23%), Positives = 153/491 (31%), Gaps = 94/491 (19%) Query: 1220 PLEGPNLTPEASPDPLPEPPLASVEVPDKPSGSPGQPPS--PAPSPVPEPDAQAEDVAPP 1277 P+ P+ P LP P + +P P SP PPS PSP P +QA P Sbjct: 316 PVPPPDNAATPLPATLPPSPPLATPLPLAPP-SPSAPPSLQTLPSPPATPPSQA-----P 369 Query: 1278 PTMAEEEEGTTGELRSAEP--APADSRHPLTYRKTTNFALDKFLDPARPYKCTVCKESFT 1335 P+M L++ P P P + AL S Sbjct: 370 PSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSL----------QATTSLG 419 Query: 1336 QKNILLVHYNSVSHLHKMKKAAIDPSAPARGEAGAPP---TTTAATDKPFKCTVCRVSYN 1392 + H + + + PS PA +PP + P + ++ Sbjct: 420 SPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSP 479 Query: 1393 QSSTLEIHMRSVLHQTRSRGTKT--DSKIEGPERSQEEPKEGETEGEVGTEKKGPDTSGF 1450 SS L IH L S + S I P +Q + + P Sbjct: 480 LSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPP----- 534 Query: 1451 ISGLPFLSPPPPPLDLHRFPAPLFTPPV-LPPFPLVPESLLKLQQQQLLLPFYLHDLKVG 1509 + LP L+PPP L APL TP + PP P Sbjct: 535 LENLPSLAPPP----LQTASAPLTTPHLETPPCP-------------------------A 565 Query: 1510 PKLTLAGPAPVLSLPAATP----PPPPQPPKAELAEREWERPPMAKEGNEAGPSSPPDPL 1565 P A P+P+ + P TP PPPQ P A + PP+ +G + P SP Sbjct: 566 PCPLQAPPSPLTTPPPETPSSIATPPPQAPPALAS------PPL--QGLPSPPLSPLATP 617 Query: 1566 PNEAARTAAKALLENFGFELVIQYNEGKQAVPPPPTPPPPEALGGGDKLACGACGKLFSN 1625 P +A A L QA P PP PP L A A Sbjct: 618 PPQAPPXLALPPL---------------QAPPSPPASPPLSPLATPSPQAPNALAVHLLQ 662 Query: 1626 MLILKTHEEHVHRRFLP--FEALSRYAAQFRKSYDSL-YPPLAEPPKPPDGSLDS----P 1678 V F P +S A ++ SL PPL PP PP S P Sbjct: 663 APFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP 722 Query: 1679 VPHLGPPFLVP 1689 P PP P Sbjct: 723 PPQAPPPLAAP 733 Score = 53.5 bits (127), Expect = 3e-06 Identities = 99/405 (24%), Positives = 138/405 (34%), Gaps = 57/405 (14%) Query: 2326 APAPEAPPALKAPPATTPASMPLGAAPTLPRLAPVLLSGPALAQP-------PLGNLA-- 2376 AP P A P L+ PP + PAS P+ + T P P LL+ P L P P+ LA Sbjct: 726 APPPLAAPPLQVPP-SPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKP 784 Query: 2377 PFNSGPAASSGLLGLATSVLPTTTVVQTAGPGRPLPQRPM----PDQTNTSTAGTTDPVP 2432 P + PA ++ L S + P LP P+ P A P Sbjct: 785 PPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPP 844 Query: 2433 GPPTEPLGDKVSSERKPVAGPTSSSNDALKNLKALKTTVPALLGGQFLPFPLPPAGGTAP 2492 PP P + R P GP +S + L P P PP + Sbjct: 845 SPPASP--TLQAPRRPPTPGPDTSVSGPRLTL-------------ALAPGPPPPPSRSPS 889 Query: 2493 PAVFGPQLQG------AYFQQLYGM---KKGLFPMNPMIPQTLIGLLPNALLQPPPQPPE 2543 + GP L G + ++L G +G +P P + A P PP Sbjct: 890 STLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPP-PDAELAACHPAAWSRGPAPPL 948 Query: 2544 PTATAPPKP-PELPAPGEGEAGEVDELLTGSTGISTVDVTH-RYLCRQCKMAFD-GEAPA 2600 AP P P PA G G A G+ T+ T A D G +P Sbjct: 949 AFRGAPGAPLPWPPATGPGSA----------DGLCTIYETEGPESATPAPGALDPGPSPG 998 Query: 2601 TAHQRSFCFFGRGSGGSMPPPLR---VPICTYHCLACEVLLSGREALASHLRSSAHRRKA 2657 T+ ++ G G+ P R +P+ + LLS LA+ A Sbjct: 999 TSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAA--AEGAAGGSG 1056 Query: 2658 APPQGGPPISITNAATAASAAVAFAKEEARLPHTDSNPKTTTTST 2702 P G +T A AA + + L D + + T+ T Sbjct: 1057 GGPGGAEGGGVTGGARAALSDAELGRWAELLSPLDESRASITSVT 1101 Score = 50.4 bits (119), Expect = 2e-05 Identities = 120/506 (23%), Positives = 174/506 (34%), Gaps = 93/506 (18%) Query: 2094 KREAPAFPYPTATLASGPQPFLPPGKEATTPTPEPPLPLLPPP-------------PPSE 2140 K +A A A A G PPG +P PP P+ P P +E Sbjct: 7 KAKAGAAARTPAARAPGLLTPRPPG------SPRPPPPVTPAALRVLGAAGAVGRKPLAE 60 Query: 2141 EEG-------PEEPPKASPESEACSLSAGDLSDSSASSLAEPESPGAGGTSGGP------ 2187 G PE P+A P A + S S AS E +P A TS GP Sbjct: 61 RAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGE-RAPPAKNTSPGPVSSPGR 119 Query: 2188 GGGTGVPDGMGQRRYRTQMSSLQLKIMKACYEAYRTPTMQ---ECEVLGEEIGLPKRVIQ 2244 GT P +GQ+ R +S+ + EA + + + G G P Sbjct: 120 ASGTTRPGPLGQKGLR--ISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTP----- 172 Query: 2245 VWFQNARAKEKKAKLQGTAAGSTGGSSEGLLAAQRTDCPYCDVKYDFYVSCRGHLFSRQH 2304 + A ++++ GT G + T+ P V S H + Sbjct: 173 -----SPAMARRSRAAGTEVG-LPRPAPSARPRPPTEGPRKSVS-----SASEHSTTEPS 221 Query: 2305 LA--KLKEAVRAQLKSESKCYDLAPAPEAPPALKAPPATTPASMPLGAAPTLPRLAPVLL 2362 A + A + S+ + P + PA P A P A P+ P+ + Sbjct: 222 PAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAP--AHPSQPKPKGLQA 279 Query: 2363 SGPALAQPPLGNLAPFNSGPAASSGLLGLATSVLPTTTVVQTAGPGRPLPQRPMPDQTNT 2422 P PP + AP GP +SS P T + RP+P PD Sbjct: 280 LRPPQVTPPRKDAAP-ALGPLSSS----------PLATPSPSGTKARPVPP---PD---- 321 Query: 2423 STAGTTDPVPGPPTEPLGDKVSSERKPVAGPTSSSNDALKNLKALKTTVPALLGGQFL-- 2480 A T P PP+ PL + P+A P+ S+ +L+ L + T P+ Sbjct: 322 -NAATPLPATLPPSPPLATPL-----PLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTP 375 Query: 2481 PFPLPPAGGTAPP-----AVFGPQLQGAYFQ-QLYGMKKGLFPMNPMIPQT--LIGLLPN 2532 P PP+ T PP ++ P LQ L ++ +P + T + + P Sbjct: 376 PMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPR 435 Query: 2533 ALLQPPPQPPEPTATAPPKPPELPAP 2558 P P +T P PP L AP Sbjct: 436 QTQASLTSPSRPASTPPDSPP-LQAP 460 Score = 45.4 bits (106), Expect = 7e-04 Identities = 24/63 (38%), Positives = 32/63 (50%), Gaps = 2/63 (3%) Query: 1219 SPLEGPNLTPEASPDPLPEPPLAS--VEVPDKPSGSPGQPPSPAPSPVPEPDAQAEDVAP 1276 SP P ++P A+P P PPLA+ ++VP P SP PS P P P A + Sbjct: 709 SPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQV 768 Query: 1277 PPT 1279 PP+ Sbjct: 769 PPS 771 Score = 44.3 bits (103), Expect = 0.002 Identities = 43/136 (31%), Positives = 55/136 (40%), Gaps = 17/136 (12%) Query: 2058 VPSPAVKPPATAT---PASLPKFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQPF 2114 +PSP P A ASLP L AP + P P + TL + +P Sbjct: 800 LPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRP- 858 Query: 2115 LPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESEACSLSAGDLSDSSASSLAE 2174 PG + + P L L P PPP P SP S +LS DL+ S+S+ + Sbjct: 859 PTPGPDTSVSGPRLTLALAPGPPPP--------PSRSPSS---TLSGPDLAGHSSSATST 907 Query: 2175 PESPGAGGTSGGPGGG 2190 PE G GP GG Sbjct: 908 PEE--LRGYDSGPEGG 921 Score = 43.9 bits (102), Expect = 0.002 Identities = 39/125 (31%), Positives = 47/125 (37%), Gaps = 22/125 (17%) Query: 2059 PSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQPFLPPG 2118 PSP V+ P + PAS P P + P+ P + P P PP Sbjct: 669 PSPPVQAPFSP-PASPPV----------SPSATPPSQAPPSLAAPPLQVPPSP-PASPPM 716 Query: 2119 KEATTPTPEPPLPLLPPP---PPSEEEGPEEPPKASPESEACSLSAGDLSDSSASSLAEP 2175 + TP P+ P PL PP PPS P P A+P L A A L P Sbjct: 717 SPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLA-------APPLQVP 769 Query: 2176 ESPGA 2180 SP A Sbjct: 770 PSPPA 774 Score = 42.4 bits (98), Expect = 0.006 Identities = 38/116 (32%), Positives = 46/116 (39%), Gaps = 16/116 (13%) Query: 605 PLGLPPGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRPDKPLEAQLLL 664 PL PP P PP P SPP P +PLA P + L LL Sbjct: 613 PLATPPPQAPPXLALPPLQAPPSPPA----------SPPLSPLATPSPQAPNALAVHLLQ 662 Query: 665 NGFHHVGAPARKFPTSAPGS--LSPDAHLPPSQL---LGSSSDSLPTSPPPDDSLS 715 F +P + P S P S +SP A PPSQ L + +P SPP +S Sbjct: 663 APFSPPPSPPVQAPFSPPASPPVSPSA-TPPSQAPPSLAAPPLQVPPSPPASPPMS 717 Score = 42.0 bits (97), Expect = 0.008 Identities = 36/132 (27%), Positives = 48/132 (36%), Gaps = 32/132 (24%) Query: 2057 GVPSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQPFLP 2116 G+PSP + P AT P + P L P +AP P P P Sbjct: 605 GLPSPPLSPLATPPPQAPPXLAL-------------PPLQAPPSP-----------PASP 640 Query: 2117 PGKEATTPTPEPPLPL--------LPPPPPSEEEGPEEPPKASPESEACSLSAGDLSDSS 2168 P TP+P+ P L PPP + P PP + P S + + + + Sbjct: 641 PLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLA 700 Query: 2169 ASSLAEPESPGA 2180 A L P SP A Sbjct: 701 APPLQVPPSPPA 712 Score = 40.8 bits (94), Expect = 0.018 Identities = 87/411 (21%), Positives = 117/411 (28%), Gaps = 66/411 (16%) Query: 1211 PSSLYFLLSPLEGPNLT--PEASPDPLPEPPLASVEVPDKPSGSPGQPPSPAPSPVPEPD 1268 P L +PL P+L P +P PL PP P + S PP AP + P Sbjct: 543 PPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPP 602 Query: 1269 AQAEDVAPPPTMAEEEEGTTGELR----SAEPAPADSRHPLTYRKTTNFALDKFLDPARP 1324 Q P +A L A P+P PA P Sbjct: 603 LQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSP----------------------PASP 640 Query: 1325 YKCTVCKESFTQKNILLVHYNSVSHLHKMKKAAIDPSAPARGEAGAPPTTTAATDKPFKC 1384 + S N L VH P +P +P T + P Sbjct: 641 PLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLA 700 Query: 1385 TVCRVSYNQSSTLEIHMRSVLHQTRSRGTKTDSKIEGPERS---QEEPKEGETEGEVGTE 1441 + L++ S + P + Q P + + Sbjct: 701 ---------APPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSA 751 Query: 1442 KKGPDTSGFISGLPFLSPPPPPLDLHRFPAPLFTPPVLPPFPLVPESLLKLQQQQLLLPF 1501 P ++ P PP PP L +PL PP P L L L P Sbjct: 752 TPPPRVPPLLAAPPLQVPPSPPASLPM--SPLAKPPPQAPPALATPPLQALPSPPASFP- 808 Query: 1502 YLHDLKVGPKLTLAGPAPVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPSSP 1561 + + A + P ATPPP P A + PP + P P Sbjct: 809 --------GQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASP--TLQAPRRP 858 Query: 1562 PDPLPNEAARTAAKALLENFGFELVIQYNEGKQAVPPPPTPPPPEALGGGD 1612 P P P+ + G L + G PPPP+ P L G D Sbjct: 859 PTPGPDTSVS----------GPRLTLALAPGP---PPPPSRSPSSTLSGPD 896 Score = 40.8 bits (94), Expect = 0.018 Identities = 37/126 (29%), Positives = 47/126 (37%), Gaps = 18/126 (14%) Query: 605 PLGLPPGLMGPGPPPPPGATP--TSPPELFQYFGPQALGQPQTPLA----GPGLRPDKPL 658 PL PP + P PP P +P T PP + L P +P A P +P Sbjct: 729 PLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQA 788 Query: 659 EAQLLLNGFHHVGAPARKFPTSAPGSLSPDAHLPPSQL----------LGSSSDSLPTSP 708 L + +P FP AP SP A LP S L L + +P SP Sbjct: 789 PPALATPPLQALPSPPASFPGQAP--FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSP 846 Query: 709 PPDDSL 714 P +L Sbjct: 847 PASPTL 852 Score = 39.3 bits (90), Expect = 0.053 Identities = 39/127 (30%), Positives = 45/127 (35%), Gaps = 22/127 (17%) Query: 606 LGLPPGLMGPGPP--PPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRPD--KPLEAQ 661 L PP + P PP PP + T PP+ L P +P A P + P P Sbjct: 699 LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVP 758 Query: 662 LLLNGFHHVGAPARKFPTSAPGSL------------SPDAHLPPSQLLGSSSDSLPTSPP 709 LL AP + P S P SL P PP Q L S S P P Sbjct: 759 PLL------AAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAP 812 Query: 710 PDDSLSL 716 S SL Sbjct: 813 FSPSASL 819 Score = 38.1 bits (87), Expect = 0.12 Identities = 46/172 (26%), Positives = 58/172 (33%), Gaps = 29/172 (16%) Query: 548 SPPEASLPPSAGDKEPKTKSSWQCKVCSYETNISRNLRIHMTSEKHMQNVLMLHQ-GLPL 606 +PP +LPP P S L T N L +H P Sbjct: 621 APPXLALPPLQAPPSPPA---------------SPPLSPLATPSPQAPNALAVHLLQAPF 665 Query: 607 GLPPGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQ-----TPLAGPGLRPDKPLEAQ 661 PP P PP + P SP P +L P +P A P + P Q Sbjct: 666 SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 725 Query: 662 LLLNGFHHVGAPARKFPTSAPGS--LSPDAHLPP--SQLLGSSSDSLPTSPP 709 + AP + P S P S +SP A PP LL + +P SPP Sbjct: 726 ----APPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPP 773 Score = 37.0 bits (84), Expect = 0.26 Identities = 71/323 (21%), Positives = 107/323 (33%), Gaps = 48/323 (14%) Query: 1862 PAGPEGPLPEPPDGEELSQAEATKAGGKEPEEKATPSPSPAHTCDQCAISFSSQDLLTSH 1921 P P P PP + L AT P P +P Q LTS Sbjct: 342 PLAPPSP-SAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSL--QTIPPIQVPHSLTS- 397 Query: 1922 RRLHFLPSLQPSAPPQLLDLPLLVFGERNPLVAATSPMPGPPLKRKHEDGSLSPTGSEAG 1981 PSLQ APP L L L AT+ + P L+ H ++SP ++A Sbjct: 398 ------PSLQ--APPSPLALSSL---------QATTSLGSPTLQATHSFLTMSPRQTQAS 440 Query: 1982 GGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQN 2041 P + P+ + + S P + L + + + + Sbjct: 441 LTSPSRP-------ASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALS 493 Query: 2042 TRARERKGQFRSTPGGVPSPAVKPP----ATATPASL--PKFNLLLGKVDDGTGREAPKR 2095 + A +P S + PP ++ P SL P +L +++ P Sbjct: 494 SLASH-------SPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPL 546 Query: 2096 EAPAFPYPTATLASGPQPFLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESE 2155 + + P T L + P P A P PP PL PPP + PP+A P Sbjct: 547 QTASAPLTTPHLETPPCP-------APCPLQAPPSPLTTPPPETPSSIATPPPQAPPALA 599 Query: 2156 ACSLSAGDLSDSSASSLAEPESP 2178 + L S + P++P Sbjct: 600 SPPLQGLPSPPLSPLATPPPQAP 622 Score = 37.0 bits (84), Expect = 0.26 Identities = 49/188 (26%), Positives = 67/188 (35%), Gaps = 41/188 (21%) Query: 1471 APLFTPPVLPPFPLVPESLLKLQQQQLLLPFYLHDLKV---GPKLTLAGPAPVLSLPAAT 1527 +PL TPP P P++ LL++ P + GP +++GP L+L Sbjct: 822 SPLATPPPQAP-PVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP 880 Query: 1528 PPPPPQPPKAELA-------EREWERPPMAKEGNEAGP------SSPPD----------- 1563 PPPP + P + L+ P G ++GP S PPD Sbjct: 881 PPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAW 940 Query: 1564 ---PLPNEAARTAAKALLE--------NFGFELVIQYNEGKQAVPPPP--TPPPPEALGG 1610 P P A R A A L + I EG ++ P P P P Sbjct: 941 SRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTS 1000 Query: 1611 GDKLACGA 1618 G K A GA Sbjct: 1001 GGKAAAGA 1008 Score = 36.6 bits (83), Expect = 0.35 Identities = 74/323 (22%), Positives = 104/323 (32%), Gaps = 39/323 (12%) Query: 1861 PPAGPEGPLPEPPDGEELSQAEATKAGGKEPEEKATPSPSPAHTCDQCAISFSSQDLLTS 1920 PP+ P+ PP + + + + P +A PSP + Q S S L + Sbjct: 369 PPSMTTPPMQAPPSLQTIPPIQVPHSL-TSPSLQAPPSPLALSSL-QATTSLGSPTLQAT 426 Query: 1921 HRRLHFLPSLQPSAPPQLLDLPLLVFGERNPLVAATSPMPGPPLKRKHEDGSLSPTGSEA 1980 H L P Q A P + PL A S PPL+ SLSP S Sbjct: 427 HSFLTMSPR-QTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQT-----SLSPAVSP- 479 Query: 1981 GGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQ 2040 L + + L+ L + +P + I + + + Q Sbjct: 480 -------------LSSPLTIHPLQALSS--LASHSPQAPLSSLIMPPLETQSSLAPPSLQ 524 Query: 2041 NTRARERKGQFRSTPGGVPSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAF 2100 A + P P PP A L +L +AP Sbjct: 525 TPPASLTTPPLENLPSLAP-----PPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTP 579 Query: 2101 PYPTATLASGPQPFLPPGKEATTPT---PEPPLPLLPPPPPSEEEGPEEPPKASPESEAC 2157 P T + + P P PP A+ P P PPL L PPP PP +P S Sbjct: 580 PPETPSSIATPPPQAPPAL-ASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPA 638 Query: 2158 SLSAGDLSDSSASSLAEPESPGA 2180 S L+ S P++P A Sbjct: 639 SPPLSPLATPS------PQAPNA 655 Score = 36.2 bits (82), Expect = 0.45 Identities = 57/238 (23%), Positives = 79/238 (33%), Gaps = 25/238 (10%) Query: 14 PSPGHNAPSLPSDTFSSSTPSDPVTKDPPAASSTSENMRSSEPGGQLLESGCGLVPPKEI 73 PSP AP P + S + P ++ PP+ ++ + S P + PP + Sbjct: 669 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSA--TPPPQA 726 Query: 74 GEPQEGPDCGHFPPNDPGVEKDKEQEEEEEGLPPMDLSNHLFFTAGGEAYL----VAK-- 127 P P PP+ P +PP+ + L A L +AK Sbjct: 727 PPPLAAPPL-QVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPP 785 Query: 128 ------LSLPGGSELLLPKGFPWGEAGIKEEPSLPF--LAYPPPSH---LTALHIQHGFD 176 L+ P L P G+A SLP LA PPP L A +Q Sbjct: 786 PQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPS 845 Query: 177 PIQGFSSSDQILSHDTSAPSPAACEERHGAFWSYQLAPNPPGDPKDGPMGNSGGNHVA 234 P + L P+P G + LAP PP P P G +A Sbjct: 846 P-----PASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLA 898 Score = 35.0 bits (79), Expect = 1.0 Identities = 31/97 (31%), Positives = 35/97 (36%), Gaps = 11/97 (11%) Query: 2061 PAVKPPAT-ATPASLPKFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQPF-LPPG 2118 P V PP A PA LG + A P P A+ P P LPP Sbjct: 283 PQVTPPRKDAAPA--------LGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPS 334 Query: 2119 KEATTPTP-EPPLPLLPPPPPSEEEGPEEPPKASPES 2154 TP P PP P PP + P PP +P S Sbjct: 335 PPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPS 371 Score = 34.7 bits (78), Expect = 1.3 Identities = 34/104 (32%), Positives = 38/104 (36%), Gaps = 27/104 (25%) Query: 605 PLGLPPGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRPDKPLEAQLLL 664 PL PP + PP P + T PP+ P AL P PL G P PL Sbjct: 568 PLQAPPSPLTTPPPETPSSIATPPPQ-----APPALASP--PLQG---LPSPPL------ 611 Query: 665 NGFHHVGAPARKFPTSAPGSLSPDAHLPPSQLLGSSSDSLPTSP 708 +P P AP P LPP Q S S P SP Sbjct: 612 -------SPLATPPPQAP----PXLALPPLQAPPSPPASPPLSP 644 Score = 34.7 bits (78), Expect = 1.3 Identities = 29/105 (27%), Positives = 39/105 (37%), Gaps = 25/105 (23%) Query: 1219 SPLEGPNLTPEASPDPLPEPPLAS--VEVPDKPSGSPG-----QPPSP------------ 1259 SP ++P A+P P P LA+ ++VP P SP +PP+P Sbjct: 814 SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLT 873 Query: 1260 ---APSPVPEPDAQAEDVAPPPTMAEEEEGTTG---ELRSAEPAP 1298 AP P P P P +A T ELR + P Sbjct: 874 LALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGP 918 Score = 34.3 bits (77), Expect = 1.7 Identities = 32/126 (25%), Positives = 41/126 (32%), Gaps = 19/126 (15%) Query: 2054 TPGGVPSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQP 2113 +P P P PP A P +P +P P P T P Sbjct: 717 SPSATPPPQAPPPLAAPPLQVPP---------------SPPASPPMSPSATPPPRVPPLL 761 Query: 2114 FLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPP-KASPESEACSLSAGDLSDSSA--- 2169 PP + +P P+ L PPP PP +A P A S S++ Sbjct: 762 AAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPM 821 Query: 2170 SSLAEP 2175 S LA P Sbjct: 822 SPLATP 827 Score = 33.9 bits (76), Expect = 2.2 Identities = 30/115 (26%), Positives = 41/115 (35%), Gaps = 12/115 (10%) Query: 2053 STPGGVP-SPAVKPPATATPA-SLPKFNLLLGKVDDGTGREAPKREAPAFPYPTATLASG 2110 S P P SP+ PP+ A P+ + P + +P P P T + Sbjct: 678 SPPASPPVSPSATPPSQAPPSLAAPPLQV----------PPSPPASPPMSPSATPPPQAP 727 Query: 2111 PQPFLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESEACSLSAGDLS 2165 P PP + +P PP+ PPP PP P S SL L+ Sbjct: 728 PPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLA 782 Score = 33.1 bits (74), Expect = 3.8 Identities = 47/161 (29%), Positives = 55/161 (34%), Gaps = 29/161 (18%) Query: 2053 STPGGVPSPAVKPPATATPASLPKFNLLLGK---VDDGTGREAPKREAPAFPYPTATLAS 2109 ++PG V SP + T P L + L + V G EAPKR A + T S Sbjct: 109 TSPGPVSSPG-RASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDT--S 165 Query: 2110 GPQPFLPP----------GKEATTPTPEPPLPLLPPPP--------PSEEEGPEEPPKAS 2151 GP P P G E P P P PP SE E P A Sbjct: 166 GPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAAR 225 Query: 2152 PESEA---CSLSAGDLSDSSASSLAEP--ESPGAGGTSGGP 2187 A A SSA+ L+ P P A GT P Sbjct: 226 RRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAP 266 Score = 33.1 bits (74), Expect = 3.8 Identities = 27/96 (28%), Positives = 35/96 (36%), Gaps = 19/96 (19%) Query: 345 PPSPPTATWDPSPTQAKESPVAAGEAGPDWFPEGQEEDGGLCPPLN---------QSSPT 395 PPSPP QA SP A+ P P Q PPL SP+ Sbjct: 668 PPSPPV--------QAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPS 719 Query: 396 SKEGGTLPAPVGSP--EDPSDPPQPYRLADDYTPAP 429 + P P+ +P + P PP ++ TP P Sbjct: 720 ATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPP 755 Score = 32.7 bits (73), Expect = 5.0 Identities = 30/111 (27%), Positives = 40/111 (36%), Gaps = 1/111 (0%) Query: 605 PLGLPPGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRPDKPLEAQLLL 664 P PP + P PP P ++ +L P +PLA L+ L + L Sbjct: 365 PSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQ 424 Query: 665 NGFHHVGAPARKFPTSAPGSLSPDAHLPPSQLLGSSSDSLPTSPPPDDSLS 715 + R+ S P A PP + SLP SPP SLS Sbjct: 425 ATHSFLTMSPRQTQASLTSPSRP-ASTPPDSPPLQAPLSLPASPPLQTSLS 474 Score = 32.7 bits (73), Expect = 5.0 Identities = 51/195 (26%), Positives = 65/195 (33%), Gaps = 61/195 (31%) Query: 2060 SPAVKPPATATPASLPKFNLLLGKVDDGTGR--------EAPKREAPAFPYPTATLAS-- 2109 +P PP + +P+S L G T P+ A A P P A LA+ Sbjct: 877 APGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACH 936 Query: 2110 ------GPQPFLPPGKEATTPTPEPPLPLLPPPPPS---------EEEGPEEP------- 2147 GP P L A P PLP P P E EGPE Sbjct: 937 PAAWSRGPAPPL-----AFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGAL 991 Query: 2148 -PKASPESEACSLSAGDLSDSSASSLAEP---ESP--------------------GAGGT 2183 P SP + +AG + +S+ S + E P A G Sbjct: 992 DPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGA 1051 Query: 2184 SGGPGGGTGVPDGMG 2198 +GG GGG G +G G Sbjct: 1052 AGGSGGGPGGAEGGG 1066 Score = 32.0 bits (71), Expect = 8.5 Identities = 63/257 (24%), Positives = 87/257 (33%), Gaps = 56/257 (21%) Query: 2326 APAPEAPPALKAPPATTPA--SMPLGAAPTLPRLAPVLLSGPALAQPPLGNLAPFNSGPA 2383 A A PA +AP TP P P P VL + A+ + PL A Sbjct: 10 AGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAG------ 63 Query: 2384 ASSGLLGLATSVLPTTTVVQTAGPGRPLPQRPMPDQTNTSTAGTT--DPVPGPPTEPLGD 2441 G+ + +P + AGP T +AGT+ +P PP G+ Sbjct: 64 ------GIGGATIPESA--PRAGP--------------TRSAGTSSRNPASRPPASGRGE 101 Query: 2442 KVSSERKPVAGPTSSSNDALKNLKALKTTVPALLGGQFLPFPLPP--AGGTAPPAVFGPQ 2499 + + GP SS +A TT P LG + L A G A A Sbjct: 102 RAPPAKNTSPGPVSSPG------RASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSA 155 Query: 2500 LQGAYFQQLYGMKKGLFPMNPMIPQ-----TLIGL---LPNALLQPPPQPPEPT------ 2545 L + G G P M + T +GL P+A +PP + P + Sbjct: 156 LSAGARRDTSGPTPGT-PSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 214 Query: 2546 -ATAPPKPPELPAPGEG 2561 +T P P P G Sbjct: 215 HSTTEPSPAARRRPSAG 231 >gi|134284361 LIM homeobox protein 6 isoform 2 [Homo sapiens] Length = 377 Score = 68.9 bits (167), Expect = 6e-11 Identities = 40/112 (35%), Positives = 59/112 (52%), Gaps = 9/112 (8%) Query: 1964 LKRKHEDGSLSPTGSEAGGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDC 2023 LKR E+G+ + +P KR RT+ EQL+++ + QD+NP + L Sbjct: 221 LKRAAENGNGLTLEGAVPSEQDSQPKPAKRARTSFTAEQLQVMQAQFAQDNNPDAQTLQK 280 Query: 2024 ISEEVGLKKRVVQVWFQNTRARERKGQFRSTPGGVPSPAVKPPATATPASLP 2075 +++ GL +RV+QVWFQN RAR +K P V PP+ A P+ LP Sbjct: 281 LADMTGLSRRVIQVWFQNCRARHKK--------HTPQHPV-PPSGAPPSRLP 323 Score = 52.8 bits (125), Expect = 5e-06 Identities = 25/57 (43%), Positives = 36/57 (63%) Query: 2200 RRYRTQMSSLQLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKK 2256 +R RT ++ QL++M+A + P Q + L + GL +RVIQVWFQN RA+ KK Sbjct: 249 KRARTSFTAEQLQVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHKK 305 Score = 50.1 bits (118), Expect = 3e-05 Identities = 25/72 (34%), Positives = 40/72 (55%) Query: 1726 PAGRRFSRTKFTEFQTQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKAR 1785 P + +RT FT Q Q +Q+ F P +++LA + GL+ RV+ VWFQN R + + Sbjct: 245 PKPAKRARTSFTAEQLQVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHK 304 Query: 1786 KNACEGGSMPTG 1797 K+ + P+G Sbjct: 305 KHTPQHPVPPSG 316 >gi|134284359 LIM homeobox protein 6 isoform 1 [Homo sapiens] Length = 392 Score = 68.9 bits (167), Expect = 6e-11 Identities = 40/112 (35%), Positives = 59/112 (52%), Gaps = 9/112 (8%) Query: 1964 LKRKHEDGSLSPTGSEAGGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDC 2023 LKR E+G+ + +P KR RT+ EQL+++ + QD+NP + L Sbjct: 221 LKRAAENGNGLTLEGAVPSEQDSQPKPAKRARTSFTAEQLQVMQAQFAQDNNPDAQTLQK 280 Query: 2024 ISEEVGLKKRVVQVWFQNTRARERKGQFRSTPGGVPSPAVKPPATATPASLP 2075 +++ GL +RV+QVWFQN RAR +K P V PP+ A P+ LP Sbjct: 281 LADMTGLSRRVIQVWFQNCRARHKK--------HTPQHPV-PPSGAPPSRLP 323 Score = 52.8 bits (125), Expect = 5e-06 Identities = 25/57 (43%), Positives = 36/57 (63%) Query: 2200 RRYRTQMSSLQLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKK 2256 +R RT ++ QL++M+A + P Q + L + GL +RVIQVWFQN RA+ KK Sbjct: 249 KRARTSFTAEQLQVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHKK 305 Score = 50.1 bits (118), Expect = 3e-05 Identities = 25/72 (34%), Positives = 40/72 (55%) Query: 1726 PAGRRFSRTKFTEFQTQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKAR 1785 P + +RT FT Q Q +Q+ F P +++LA + GL+ RV+ VWFQN R + + Sbjct: 245 PKPAKRARTSFTAEQLQVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHK 304 Query: 1786 KNACEGGSMPTG 1797 K+ + P+G Sbjct: 305 KHTPQHPVPPSG 316 >gi|4505007 LIM homeobox transcription factor 1, beta [Homo sapiens] Length = 372 Score = 68.2 bits (165), Expect = 1e-10 Identities = 38/108 (35%), Positives = 59/108 (54%), Gaps = 5/108 (4%) Query: 1946 FGERNPLVAATSPMPGPPLKRKHEDGSLSPT---GSEAGGGGEG--EPPRDKRLRTTILP 2000 + + L+++ SP +K + EDG + P GS++ G G+ +P R KR RT + Sbjct: 146 YEKEKDLLSSVSPDESDSVKSEDEDGDMKPAKGQGSQSKGSGDDGKDPRRPKRPRTILTT 205 Query: 2001 EQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQNTRARERK 2048 +Q + S P RK+ + ++ E GL RVVQVWFQN RA+ +K Sbjct: 206 QQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKK 253 Score = 58.9 bits (141), Expect = 6e-08 Identities = 39/105 (37%), Positives = 51/105 (48%), Gaps = 1/105 (0%) Query: 2153 ESEACSLSAGDLSDSSASSLAEPE-SPGAGGTSGGPGGGTGVPDGMGQRRYRTQMSSLQL 2211 E + S + D SDS S + + P G S G G D +R RT +++ Q Sbjct: 149 EKDLLSSVSPDESDSVKSEDEDGDMKPAKGQGSQSKGSGDDGKDPRRPKRPRTILTTQQR 208 Query: 2212 KIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKK 2256 + KA +E P + E L E GL RV+QVWFQN RAK KK Sbjct: 209 RAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKK 253 Score = 43.9 bits (102), Expect = 0.002 Identities = 26/56 (46%), Positives = 33/56 (58%) Query: 1733 RTKFTEFQTQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARKNA 1788 RT T Q +A ++ FE S+ P E LA+ GL+ RVV VWFQN R K +K A Sbjct: 200 RTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLA 255 >gi|122937321 UNC homeobox [Homo sapiens] Length = 531 Score = 68.2 bits (165), Expect = 1e-10 Identities = 117/479 (24%), Positives = 153/479 (31%), Gaps = 122/479 (25%) Query: 1729 RRFSRTKFTEFQTQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARK-- 1786 RR +RT FT +Q + L+ F S YP E LA L L V VWFQN R K RK Sbjct: 105 RRRTRTNFTGWQLEELEKAFNESHYPDVFMREALALRLDLVESRVQVWFQNRRAKWRKKE 164 Query: 1787 NACEGGSMPTGGGTGGASGCRRCHATFSCVFELVRHLKKCYDDQTLEEE--EEEAERGEE 1844 N +G P H C + EE +E E+ E+ Sbjct: 165 NTKKGPGRPAHNS----------------------HPTTCSGEPMDPEEIARKELEKMEK 202 Query: 1845 EEEVEEEEVEEEQG--LEPPAG-------------------PEGPLPEPPDGEELSQAEA 1883 ++ E+++ + QG L P G PE P P PP + A A Sbjct: 203 KKRKHEKKLLKSQGRHLHSPGGLSLHSAPSSDSDSGGGGLSPEPPEPPPPAAKG-PGAHA 261 Query: 1884 TKAGGKEP--------------------EEKATPSPSPAHTCDQCAISFSSQDLLTS-HR 1922 + A G P A P P P D+ A S + + R Sbjct: 262 SGAAGTAPAPPGEPPAPGTCDPAFYPSQRSGAGPQPRPGRPADKDAASCGPGAAVAAVER 321 Query: 1923 RLHFLPSLQPSAPPQLL-DLPLLVFGERNPLVAATSPM---PGPPLKRK----------- 1967 LP P + LL D P N AA + + PG P + Sbjct: 322 GAAGLPKASPFSVESLLSDSPPRRKAASNAAAAAAAGLDFAPGLPCAPRTLIGKGHFLLY 381 Query: 1968 ---HEDGSLSPTGSEAGGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCI 2024 G L P + GG G P+D + P + P + Sbjct: 382 PITQPLGFLVPQAALKGGAGLEPAPKDAPPAPAVPP-------------APPAQASFGAF 428 Query: 2025 SEEVGLKKRVVQVWFQNTRARERKGQFRSTPGGVPSPAVKPPATATPASLPKFNLLLGKV 2084 S G R +P V SP PA A P +L Sbjct: 429 SGPGGAPDSAFA---------------RRSPDAVASPGAPAPAPA-----PFRDLASAAA 468 Query: 2085 DDGTGREAPK--REAPAFPYPTATLASGPQPFLPPGKEATTPTPEPPLPLLPPPPPSEE 2141 +G G + PA P P + GP+P P + AT PEP P PP EE Sbjct: 469 TEGGGGDCADAGTAGPAPPPPAPSPRPGPRPPSPAEEPATCGVPEPGAAAGPSPPEGEE 527 Score = 58.5 bits (140), Expect = 8e-08 Identities = 95/400 (23%), Positives = 143/400 (35%), Gaps = 51/400 (12%) Query: 2165 SDSSASSLAEPES--PGAGGTSGGPG-----GGTGVPD----GMGQRRYRTQMSSLQLKI 2213 S ++A+S+ P P A G GG G +G PD G +RR RT + QL+ Sbjct: 61 SCAAAASVVNPTPLLPAACGV-GGDGQPFKLSDSGDPDKESPGCKRRRTRTNFTGWQLEE 119 Query: 2214 MKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAKLQGTAAGSTGGSSEG 2273 ++ + P + E L + L + +QVWFQN RAK +K + G +S Sbjct: 120 LEKAFNESHYPDVFMREALALRLDLVESRVQVWFQNRRAKWRKKENTKKGPGRPAHNSHP 179 Query: 2274 LLAAQRTDCPYCDVKYDFYVSCRGHLFSRQHLAKLKEAVRAQLKSESKCYDLAPAPEAPP 2333 + P +R+ L K+++ R K K Sbjct: 180 TTCSGEPMDP--------------EEIARKELEKMEKKKRKHEKKLLKSQGRHLHSPGGL 225 Query: 2334 ALKAPPATTPASMPLGAAPTLPRLAPVLLSGPALAQPPLGNLAPFNSGPAASSGLLGLAT 2393 +L + P++ S G +P P P GP AP G + G Sbjct: 226 SLHSAPSSDSDSGGGGLSPEPPEPPPPAAKGPGAHASGAAGTAPAPPGEPPAPGTCD--- 282 Query: 2394 SVLPTTTVVQTAGPGRPLPQRPMPDQTNTSTAGTTDPVPGPPTEPLGDKVSSERKPVAGP 2453 P Q +G G PQ P P + A + P G + P + Sbjct: 283 ---PAFYPSQRSGAG---PQ-PRPGRPADKDAASCGPGAAVAAVERGAAGLPKASPFSVE 335 Query: 2454 TSSSNDALKNLKALKTTVPALLGGQFLPFPLPPAGGTAPPAVFGPQLQGAYFQQLYGMKK 2513 + S+ + A A G F P LP AP + G +G + LY + + Sbjct: 336 SLLSDSPPRRKAASNAAAAAAAGLDFAP-GLP----CAPRTLIG---KGHFL--LYPITQ 385 Query: 2514 GLFPMNPMIPQTLIGLLPNALLQPPPQPPEPTATAPPKPP 2553 P+ ++PQ L A L+P P+ P PP PP Sbjct: 386 ---PLGFLVPQA--ALKGGAGLEPAPKDAPPAPAVPPAPP 420 Score = 56.6 bits (135), Expect = 3e-07 Identities = 124/560 (22%), Positives = 189/560 (33%), Gaps = 92/560 (16%) Query: 1921 HRRLHFLPSLQPSAPPQLLDLPLLVFGERNPLVAATSPMPGPPLKRKHEDGSLSPTGSEA 1980 H ++ L Q + +P + G AA + + P L P Sbjct: 30 HHHVYELAGHQLQSAAAAASVPFSIDGLLGGSCAAAASVVNPT--------PLLPAACGV 81 Query: 1981 GGGGE-------GEPPRD------KRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEE 2027 GG G+ G+P ++ +R RT QLE L + + + P M + ++ Sbjct: 82 GGDGQPFKLSDSGDPDKESPGCKRRRTRTNFTGWQLEELEKAFNESHYPDVFMREALALR 141 Query: 2028 VGLKKRVVQVWFQNTRARERKGQFRSTPGGVPSPAVKPPATATPASLPKFNLLLGKVDDG 2087 + L + VQVWFQN RA+ RK + G P+ P + P ++ Sbjct: 142 LDLVESRVQVWFQNRRAKWRKKENTKKGPGRPAHNSHPTTCSGEPMDP---------EEI 192 Query: 2088 TGREAPKREAPAFPYPTATLASGPQPFLPPGKEATTPTPEPPLPLLPPPPPSEEEG---- 2143 +E K E + L S + PG L L P + G Sbjct: 193 ARKELEKMEKKKRKHEKKLLKSQGRHLHSPG----------GLSLHSAPSSDSDSGGGGL 242 Query: 2144 -PEEPPKASPESEACSLSAGDLSDSSASSLAEPESPGAGGTSGGPG--GGTGVPDGMGQR 2200 PE P P ++ A + ++ + EP +PG + P G G G+ Sbjct: 243 SPEPPEPPPPAAKGPGAHASGAAGTAPAPPGEPPAPGTCDPAFYPSQRSGAGPQPRPGRP 302 Query: 2201 RYRTQMSSLQLKIMKACYEAYRTPTMQECEVLGEEIGLPKR---VIQVWFQNARAKEKKA 2257 + S P V GLPK ++ ++ + K A Sbjct: 303 ADKDAASC--------------GPGAAVAAVERGAAGLPKASPFSVESLLSDSPPRRKAA 348 Query: 2258 KLQGTAAGSTGGSSEGLLAAQRTDCPYCDVKYDFYVSCRGHLFSRQHLAKLKEAV-RAQL 2316 AA + + GL A RT + +GH L V +A L Sbjct: 349 SNAAAAAAAGLDFAPGLPCAPRT------------LIGKGHFLLYPITQPLGFLVPQAAL 396 Query: 2317 KSESKCYDLAPAP-EAPPALKAPPATTPASMPLGA------AP--TLPRLAPVLLSGPAL 2367 K + L PAP +APPA PPA PA GA AP R +P ++ P Sbjct: 397 KGGA---GLEPAPKDAPPAPAVPPA-PPAQASFGAFSGPGGAPDSAFARRSPDAVASPGA 452 Query: 2368 AQPPLGNLAPFNSGPAASSGLLGLATSVLPTTTVVQTAGPGRPLPQRPMPDQTNTSTAGT 2427 P S A G A + A RP P+ P P + +T G Sbjct: 453 PAPAPAPFRDLASAAATEGGGGDCADAGTAGPAPPPPAPSPRPGPRPPSPAE-EPATCGV 511 Query: 2428 TDP-VPGPPTEPLGDKVSSE 2446 +P P+ P G+++ + Sbjct: 512 PEPGAAAGPSPPEGEELDMD 531 Score = 33.9 bits (76), Expect = 2.2 Identities = 63/268 (23%), Positives = 80/268 (29%), Gaps = 44/268 (16%) Query: 1356 AAIDPSAPARGEAGAPPTTTAATDKPFKCTVCRVSYNQSSTLEIHMRSVLHQTR-SRGTK 1414 AA P A A G AG P P C +S Q R R Sbjct: 253 AAKGPGAHASGAAGTAPAPPGEPPAPGTCDPAFYPSQRSGAGP--------QPRPGRPAD 304 Query: 1415 TDSKIEGPERSQEEPKEGETEGEVGTEKKGPDTSGFISGLPFLSPPPPPLDLHRFPAPLF 1474 D+ GP + + G G K P + + L SPP + A Sbjct: 305 KDAASCGPGAAVAAVERGAA----GLPKASPFS---VESLLSDSPPRRKAASNAAAAAAA 357 Query: 1475 TPPVLPPFPLVPESLLKLQQQQLLLPFYLHDLKVGPKLTLAGPAPVLSLPAATPPPPPQP 1534 P P P +L+ + LL P + P+ L G A + P PP P P Sbjct: 358 GLDFAPGLPCAPRTLIG-KGHFLLYPITQPLGFLVPQAALKGGAGLEPAPKDAPPAPAVP 416 Query: 1535 PKAELAEREWERPPMAKEGNEAGPSSPPD------------------PLPNEAARTAAKA 1576 P P A G +GP PD P P A+ A Sbjct: 417 PAP---------PAQASFGAFSGPGGAPDSAFARRSPDAVASPGAPAPAPAPFRDLASAA 467 Query: 1577 LLENFGFELVIQYNEGKQAVPPPPTPPP 1604 E G + G PP P+P P Sbjct: 468 ATEGGGGDCADAGTAGPAPPPPAPSPRP 495 >gi|33569216 LIM homeobox 9 isoform 1 [Homo sapiens] Length = 397 Score = 68.2 bits (165), Expect = 1e-10 Identities = 63/202 (31%), Positives = 86/202 (42%), Gaps = 36/202 (17%) Query: 1904 TCDQCAIS------FSSQDLLTSHRRLHFLPSLQPSAPPQL--LDLPLLVFGERNPLVAA 1955 TC C + F +D L + R HF LQ PPQL +L G P Sbjct: 160 TCSTCNKTLTTGDHFGMKDSLV-YCRAHFETLLQGEYPPQLSYTELAAKSGGLALPYFNG 218 Query: 1956 TSPMP-GPPLKRK----------HEDGSLSPTGSEAGGGGEGEPP--RDKRLRTTILPEQ 2002 T + G P KRK + G + PP + KR+RT+ Q Sbjct: 219 TGTVQKGRPRKRKSPALGVDIVNYNSGCNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQ 278 Query: 2003 LEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQNTRARERKGQFRSTPGGV---- 2058 L + ++ + NP K L ++++ GL KRV+QVWFQN RA+ R+ R GGV Sbjct: 279 LRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNLLRQENGGVDKAD 338 Query: 2059 ----PSP------AVKPPATAT 2070 P+P A+ PP TAT Sbjct: 339 GTSLPAPPSADSGALTPPGTAT 360 Score = 54.7 bits (130), Expect = 1e-06 Identities = 30/88 (34%), Positives = 43/88 (48%) Query: 2194 PDGMGQRRYRTQMSSLQLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAK 2253 P +R RT QL+ MK+ + P ++ + L ++ GL KRV+QVWFQNARAK Sbjct: 262 PPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAK 321 Query: 2254 EKKAKLQGTAAGSTGGSSEGLLAAQRTD 2281 ++ L+ G L A D Sbjct: 322 FRRNLLRQENGGVDKADGTSLPAPPSAD 349 Score = 51.2 bits (121), Expect = 1e-05 Identities = 27/70 (38%), Positives = 39/70 (55%), Gaps = 2/70 (2%) Query: 1733 RTKFTEFQTQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARKNAC--E 1790 RT F Q + ++S+F + P ++++LA GL RV+ VWFQNAR K R+N E Sbjct: 271 RTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNLLRQE 330 Query: 1791 GGSMPTGGGT 1800 G + GT Sbjct: 331 NGGVDKADGT 340 >gi|62241033 LIM homeobox 9 isoform 2 [Homo sapiens] Length = 388 Score = 68.2 bits (165), Expect = 1e-10 Identities = 63/202 (31%), Positives = 86/202 (42%), Gaps = 36/202 (17%) Query: 1904 TCDQCAIS------FSSQDLLTSHRRLHFLPSLQPSAPPQL--LDLPLLVFGERNPLVAA 1955 TC C + F +D L + R HF LQ PPQL +L G P Sbjct: 151 TCSTCNKTLTTGDHFGMKDSLV-YCRAHFETLLQGEYPPQLSYTELAAKSGGLALPYFNG 209 Query: 1956 TSPMP-GPPLKRK----------HEDGSLSPTGSEAGGGGEGEPP--RDKRLRTTILPEQ 2002 T + G P KRK + G + PP + KR+RT+ Q Sbjct: 210 TGTVQKGRPRKRKSPALGVDIVNYNSGCNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQ 269 Query: 2003 LEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQNTRARERKGQFRSTPGGV---- 2058 L + ++ + NP K L ++++ GL KRV+QVWFQN RA+ R+ R GGV Sbjct: 270 LRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNLLRQENGGVDKAD 329 Query: 2059 ----PSP------AVKPPATAT 2070 P+P A+ PP TAT Sbjct: 330 GTSLPAPPSADSGALTPPGTAT 351 Score = 54.7 bits (130), Expect = 1e-06 Identities = 30/88 (34%), Positives = 43/88 (48%) Query: 2194 PDGMGQRRYRTQMSSLQLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAK 2253 P +R RT QL+ MK+ + P ++ + L ++ GL KRV+QVWFQNARAK Sbjct: 253 PPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAK 312 Query: 2254 EKKAKLQGTAAGSTGGSSEGLLAAQRTD 2281 ++ L+ G L A D Sbjct: 313 FRRNLLRQENGGVDKADGTSLPAPPSAD 340 Score = 51.2 bits (121), Expect = 1e-05 Identities = 27/70 (38%), Positives = 39/70 (55%), Gaps = 2/70 (2%) Query: 1733 RTKFTEFQTQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARKNAC--E 1790 RT F Q + ++S+F + P ++++LA GL RV+ VWFQNAR K R+N E Sbjct: 262 RTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNLLRQE 321 Query: 1791 GGSMPTGGGT 1800 G + GT Sbjct: 322 NGGVDKADGT 331 >gi|47132519 Ras association and pleckstrin homology domains 1 isoform 1 [Homo sapiens] Length = 1250 Score = 67.0 bits (162), Expect = 2e-10 Identities = 122/479 (25%), Positives = 159/479 (33%), Gaps = 75/479 (15%) Query: 1225 NLTPEASPDP-LPEPPLASVEVPDKPSGSPGQPPSPAPSPVPEPDAQAEDVAPPPTMAEE 1283 +L P SP P + P AS P P P PP P P P P PPP + + Sbjct: 604 SLVPPLSPQPKIVTPYTASQPSPPLPPPPP-PPPPPPPPPPP----------PPPPLPSQ 652 Query: 1284 EEGTTGELRSAEPAPADSRHPLTYRKTTNFALDKFLDPARPYKCTVCKESFTQKNILLVH 1343 + G SA P + + + F P P +S + K +LV Sbjct: 653 SAPSAG---SAAPMFVKYSTITRLQNASQHSGALFKPPTPP-----VMQSQSVKPQILVP 704 Query: 1344 YNSVSHLHKMKKAAIDPSAPARGEAGAPPTTTAATDKPFKCTVCRVSYNQSST----LEI 1399 N V + P P PP T + K C S Q S L+I Sbjct: 705 PNGV----------VPPPPPP-----PPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKI 749 Query: 1400 HMRSVLHQTRSRGTKTDSKIEGPERSQEEPKEGET-EGEVGTEKKGPDTSGFISGLPFLS 1458 H + Q I P Q PK T T+ P + + P + Sbjct: 750 HQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQ--AAPPTPT 807 Query: 1459 PPPPPLDLH-RFPAPLFTP-PVLPPFPLVPESLLKLQQQQLLLPFYLHDLKVGPKLTLAG 1516 PP PP FPA P P PP P+ P +L K QQ P P L+ Sbjct: 808 PPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPK-QQSFCAKP---------PPSPLSP 857 Query: 1517 PAPVLSLPAATPPPPPQPPKAEL-------AEREWERPPMAKEGNEAGPSSPPDPLPNEA 1569 V+ A+ PPPP PP E A + PP K + PSS P P P+ Sbjct: 858 VPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFP 917 Query: 1570 ARTAAKALLENFGFELVIQYNEGKQAVPPPPTPPPPEALGGGDKLACGACGKLFSNMLI- 1628 +L + VP PP PPPP A DK G+ GK S Sbjct: 918 PPPPESSL---------VFPPPPPSPVPAPPPPPPPTASPTPDK--SGSPGKKTSKTSSP 966 Query: 1629 --LKTHEEHVHRRFLPFEALSRYAAQFRKSYDSLYPPLAEPPKPPDGSLDSPVPHLGPP 1685 K + + + + R S DSL P + S ++ P PP Sbjct: 967 GGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPP 1025 Score = 58.9 bits (141), Expect = 6e-08 Identities = 66/262 (25%), Positives = 90/262 (34%), Gaps = 37/262 (14%) Query: 2325 LAPAPEAPPALKAPPATTPASMPLGAAPTLPRLAP------------VLLSGPALAQPPL 2372 + P P PP P + P AP+LP+ + + P PP Sbjct: 708 VVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPP 767 Query: 2373 GNLAPFN-SGPAASSGLLGLATSVLPTTTVVQTAGPGRPLPQRPMPDQTNTSTAGTTDPV 2431 AP P + TS VV A P P P P+P + Sbjct: 768 PIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTP--PVPPAKKQPAFPASYIP 825 Query: 2432 PGPPTEPLGDKVSSERKPVAGPTSSSNDAL--KNLKALKTTVPAL---LGGQFLPFPLPP 2486 P PPT P+ PV PT + K + + VP++ + QF P P PP Sbjct: 826 PSPPTPPV---------PVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPP 876 Query: 2487 AGGTAP----PAVFGPQLQGAYFQQLYGMKKGLFPMNPMIPQTLIGLLPNALLQPPPQPP 2542 A + P PA PQ A + + +P P P + L PP PP Sbjct: 877 AMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPP----PESSLVFPPPPP 932 Query: 2543 EPTATAPPKPPELPAPGEGEAG 2564 P PP PP +P ++G Sbjct: 933 SPVPAPPPPPPPTASPTPDKSG 954 Score = 45.4 bits (106), Expect = 7e-04 Identities = 62/254 (24%), Positives = 89/254 (35%), Gaps = 44/254 (17%) Query: 2325 LAPAPEAPPALKAPPATTPASMPLGAAPTLPRLAPVLLSGPALAQPPLGNLAPFNSGPAA 2384 + P+P PP + PP T P A P L+PV P++ + P + PA Sbjct: 824 IPPSPPTPP-VPVPPPTLPKQQSFCAKPPPSPLSPV----PSVVKQIASQFPPPPTPPAM 878 Query: 2385 SSG-LLGLATSVLPTTTVVQTAGP-----GRPLPQR----PMPDQTNTSTAGTTDPVPGP 2434 S L + +V P + A P P+P P P+ + PVP P Sbjct: 879 ESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAP 938 Query: 2435 PTEPLGDKVSSERKPVAGPTSSSNDALKNLKALKTTVPALLGGQFLPFPLPPAGGTAPPA 2494 P P P A PT + + K KT+ P GG PP Sbjct: 939 PPPP---------PPTASPTPDKSGS-PGKKTSKTSSP---------------GGKKPPP 973 Query: 2495 VFGPQLQGAYFQQLYGMKKGLFPMNPMIPQTLIGLLPNALLQPPPQPPEPTATAPPKPPE 2554 PQ + + + G + P P + + P A P + P APPKP + Sbjct: 974 T--PQ-RNSSIKSSSGAEHPE-PKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGK 1029 Query: 2555 LPAPGEGEAGEVDE 2568 L G G + + Sbjct: 1030 LNLSGVNLPGVLQQ 1043 Score = 45.4 bits (106), Expect = 7e-04 Identities = 30/103 (29%), Positives = 47/103 (45%), Gaps = 4/103 (3%) Query: 1224 PNLTPEASPDPLPEPPLAS-VEVPDKPSGSPGQPPSPAPSPVPEPD---AQAEDVAPPPT 1279 P+ P SPD P PP +S V P PS P PP P P+ P PD + + + + Sbjct: 906 PSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSS 965 Query: 1280 MAEEEEGTTGELRSAEPAPADSRHPLTYRKTTNFALDKFLDPA 1322 ++ T + S+ + + + HP R + + + KF PA Sbjct: 966 PGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPA 1008 Score = 45.1 bits (105), Expect = 0.001 Identities = 68/279 (24%), Positives = 106/279 (37%), Gaps = 41/279 (14%) Query: 2328 APEAPPALKAPPATTPASMPLGAAPTLPRLAPVLLSGPALAQPPLGNLAPFNSGPAASSG 2387 AP++PPA+KA P P+S+P+ +P P P + PP + P P + Sbjct: 891 APQSPPAVKAKPKWQPSSIPV-PSPDFPPPPP---ESSLVFPPPPPSPVPAPPPPPPPTA 946 Query: 2388 LLGLATSVLPTTTVVQTAGPGRPLPQRPMPDQTNTSTAGTTDPVPGPPTEPLGDKVSSER 2447 S P +T+ PG P P Q N+S ++ P P D + S+ Sbjct: 947 SPTPDKSGSPGKKTSKTSSPGGKKP--PPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKF 1004 Query: 2448 KPVAGPTSSSNDALKNLKALKTTVPALLGGQFLPFPLPPAGGTAPPAVFGPQLQGAYFQQ 2507 P A S S K T+P PPA APP L G Sbjct: 1005 TPPAESGSPS----------KETLP------------PPA---APPKPGKLNLSGVNLPG 1039 Query: 2508 LYGMKKGLFPMNPMIPQTLIGLLPNALLQPPPQPPEPTATAPPKPPELPAPGEGEAGEVD 2567 + +++G + L G +++++ P P + PP ELP P E+ Sbjct: 1040 V--LQQGCVSAKAPV---LSGRGKDSVVEFPSPPSDSDFPPPPPETELPLP----PIEIP 1090 Query: 2568 ELLTGSTGISTVDVTHRYLCRQCKMAFDGEAPATAHQRS 2606 + +G+T V V + + KM+ P T +R+ Sbjct: 1091 AVFSGNTS-PKVAVVNPQPQQWSKMSVKKAPPPTRPKRN 1128 Score = 42.7 bits (99), Expect = 0.005 Identities = 84/380 (22%), Positives = 125/380 (32%), Gaps = 77/380 (20%) Query: 1844 EEEEVEEEEVEEEQGLEPPAGPEGPLPEPPDGEELSQAEATKAGGKEPEEKATPSPSPAH 1903 + + V+ + + G+ PP P P P P G ++Q + P+ A P P H Sbjct: 693 QSQSVKPQILVPPNGVVPPPPP--PPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIH 750 Query: 1904 TCDQCAISFSSQDLLTSHRRLHFLPS-LQPSAPPQ-LLDLPLLVFGER-NPLVA-ATSPM 1959 + +Q + +P+ L P APP+ L+ +P + P+V A P Sbjct: 751 Q-----VQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPT 805 Query: 1960 PGPPLKRKHEDGSLSPTGSEAGGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRK 2019 P PP+ P + PP + P L Q S + Sbjct: 806 PTPPVP---------PAKKQPAFPASYIPPSPPTPPVPVPPPTLP------KQQSFCAKP 850 Query: 2020 MLDCISEEVGLKKRVVQVWFQNTRARERKGQFRS--TPGGVPSPAVKP-PATATPASLPK 2076 +S + K++ QF TP + S +KP PA P S P Sbjct: 851 PPSPLSPVPSVVKQIAS-------------QFPPPPTPPAMESQPLKPVPANVAPQSPPA 897 Query: 2077 FNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQPFLPPGKEATTPTPEPPLPLLPPP 2136 + PK + + P P+ P PP P PE L PPP Sbjct: 898 V------------KAKPKWQPSSIPVPS--------PDFPP------PPPESSLVFPPPP 931 Query: 2137 P-PSEEEGPEEPPKASPESEACSLSAGDLSDSSASSLAEPESPGAGGTSGGPGGGTGVPD 2195 P P P PP ASP D S S ++ SPG P + + Sbjct: 932 PSPVPAPPPPPPPTASP--------TPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKS 983 Query: 2196 GMGQRRYRTQMSSLQLKIMK 2215 G + S+ + K Sbjct: 984 SSGAEHPEPKRPSVDSLVSK 1003 Score = 41.6 bits (96), Expect = 0.011 Identities = 86/370 (23%), Positives = 122/370 (32%), Gaps = 66/370 (17%) Query: 1224 PNLTPEASPDPLPEPPLASVEVPDKPSGSPGQPPSPAPSPVPE---PDAQAEDVAPPPTM 1280 P +T A P P P P A + S P PP+P P PVP P Q+ PPP+ Sbjct: 796 PVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTP-PVPVPPPTLPKQQSFCAKPPPSP 854 Query: 1281 AEEEEGTTGELRSAEPAPADSRHPLTYRKTTNFALDKFLDPARPYKCTVCKES------- 1333 ++ S P P T A++ P +P V +S Sbjct: 855 LSPVPSVVKQIASQFPPP-----------PTPPAMES--QPLKPVPANVAPQSPPAVKAK 901 Query: 1334 -FTQKNILLVHYNSVSHLHKMKKAAIDPSAPARGEAGAPPTTTAATDKPFKCTVCRVSYN 1392 Q + + V P P+ A PP A+ P K S Sbjct: 902 PKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSG----SPG 957 Query: 1393 QSSTLEIHMRSVLHQTRSRGTKTDSKIEGPERSQEEPKEGETEGEVGTEKKGPDTSGFIS 1452 + ++ +T S G K + P Q + G E K P +S Sbjct: 958 KKTS----------KTSSPGGK-----KPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVS 1002 Query: 1453 GLPFLSPPPPPLDLHRFPAPLFTPPVLPPFPLVPESLLKLQQQQLLLPFYLHDLKV---G 1509 PP + PP PP P KL + LP L V Sbjct: 1003 KF------TPPAESGSPSKETLPPPAAPPKP------GKLNLSGVNLPGVLQQGCVSAKA 1050 Query: 1510 PKLTLAGPAPVLSLPAATPPP----PPQPPKAELAEREWERPPMAKEGNEAGPSSPPDPL 1565 P L+ G V+ P +PP PP PP+ EL E P + GN + + +P Sbjct: 1051 PVLSGRGKDSVVEFP--SPPSDSDFPPPPPETELPLPPIEIPAVF-SGNTSPKVAVVNPQ 1107 Query: 1566 PNEAARTAAK 1575 P + ++ + K Sbjct: 1108 PQQWSKMSVK 1117 Score = 38.9 bits (89), Expect = 0.070 Identities = 20/61 (32%), Positives = 27/61 (44%) Query: 2101 PYPTATLASGPQPFLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESEACSLS 2160 PY + PQP + A+ P+P P P PPPPP P PP S + + + Sbjct: 601 PYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSA 660 Query: 2161 A 2161 A Sbjct: 661 A 661 Score = 37.7 bits (86), Expect = 0.15 Identities = 23/58 (39%), Positives = 25/58 (43%), Gaps = 6/58 (10%) Query: 2098 PAFPYP---TATLASGPQPFLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPKASP 2152 P P P T AS P P LPP P P PP P PPPPP + A+P Sbjct: 608 PLSPQPKIVTPYTASQPSPPLPP---PPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAP 662 Score = 35.4 bits (80), Expect = 0.77 Identities = 14/28 (50%), Positives = 15/28 (53%) Query: 2537 PPPQPPEPTATAPPKPPELPAPGEGEAG 2564 PPP PP P PP PP LP+ AG Sbjct: 631 PPPPPPPPPPPPPPPPPPLPSQSAPSAG 658 Score = 33.1 bits (74), Expect = 3.8 Identities = 18/40 (45%), Positives = 20/40 (50%), Gaps = 2/40 (5%) Query: 2520 PMIPQTLIGLLPNALLQP-PPQPPEPTATAPPKPPELPAP 2558 P+ PQ I + P QP PP PP P PP PP P P Sbjct: 608 PLSPQPKI-VTPYTASQPSPPLPPPPPPPPPPPPPPPPPP 646 Score = 33.1 bits (74), Expect = 3.8 Identities = 12/24 (50%), Positives = 13/24 (54%) Query: 2537 PPPQPPEPTATAPPKPPELPAPGE 2560 PPP PP P PP PP P P + Sbjct: 629 PPPPPPPPPPPPPPPPPPPPLPSQ 652 Score = 33.1 bits (74), Expect = 3.8 Identities = 28/100 (28%), Positives = 34/100 (34%), Gaps = 13/100 (13%) Query: 345 PPSPPTATWDPSPTQAKESPVAAGEAGPDW--------FPEGQEEDGGL----CPPLNQS 392 PP PP P P +S +AG A P + + G L PP+ QS Sbjct: 635 PPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQS 694 Query: 393 SPTSKEGGTLP-APVGSPEDPSDPPQPYRLADDYTPAPAA 431 + P V P P PP P PAP A Sbjct: 695 QSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCA 734 Score = 33.1 bits (74), Expect = 3.8 Identities = 33/137 (24%), Positives = 47/137 (34%), Gaps = 22/137 (16%) Query: 2055 PGGVPSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQPF 2114 P VP+P PP TA+P G++ K +P P T PQ Sbjct: 932 PSPVPAPPPPPPPTASPTP---------DKSGSPGKKTSKTSSPGGKKPPPT----PQRN 978 Query: 2115 LPPGKEATTPTPEPPLPLLPP-----PPPSEEEGPEE----PPKASPESEACSLSAGDLS 2165 + PEP P + PP+E P + PP A P+ +LS +L Sbjct: 979 SSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLP 1038 Query: 2166 DSSASSLAEPESPGAGG 2182 ++P G Sbjct: 1039 GVLQQGCVSAKAPVLSG 1055 Score = 32.7 bits (73), Expect = 5.0 Identities = 33/118 (27%), Positives = 40/118 (33%), Gaps = 13/118 (11%) Query: 610 PGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRP-DKPLEAQLLLNGFH 668 P L P PPPPP P PP P L P AG K L N Sbjct: 626 PPLPPPPPPPPPPPPPPPPP-------PPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQ 678 Query: 669 HVGAPAR--KFPTSAPGSLSPDAHLPPSQLLGSSSDSLPTSPPPDDSLSLKVFRCLVC 724 H GA + P S+ P +PP+ G P PPP ++ + C Sbjct: 679 HSGALFKPPTPPVMQSQSVKPQILVPPN---GVVPPPPPPPPPPTPGSAMAQLKPAPC 733 Score = 32.3 bits (72), Expect = 6.5 Identities = 32/104 (30%), Positives = 38/104 (36%), Gaps = 31/104 (29%) Query: 617 PPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRPDKPLEAQLLLNGFHHVGAPARK 676 PPPPP P PP P P A P PDK G+P +K Sbjct: 928 PPPPPSPVPAPPP-------------PPPPTASP--TPDKS-------------GSPGKK 959 Query: 677 -FPTSAPGSLSPDAHLPPSQLLGSSSDSLPTSP--PPDDSLSLK 717 TS+PG P + + SSS + P P DSL K Sbjct: 960 TSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSK 1003 Score = 32.0 bits (71), Expect = 8.5 Identities = 28/93 (30%), Positives = 36/93 (38%), Gaps = 18/93 (19%) Query: 609 PPGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGL----RPDKPLEAQLLL 664 P G++ P PPPPP TP S A+ Q + P L P PL+ + Sbjct: 705 PNGVVPPPPPPPPPPTPGS-----------AMAQLKPAPCAPSLPQFSAPPPPLKIHQVQ 753 Query: 665 NGFHHVGAPARKFPTSAPGSLSPDAHLPPSQLL 697 + V P P P L P A PP L+ Sbjct: 754 H-ITQVAPPTPPPPPPIPAPLPPQA--PPKPLV 783 Score = 32.0 bits (71), Expect = 8.5 Identities = 36/137 (26%), Positives = 46/137 (33%), Gaps = 27/137 (19%) Query: 345 PPSPPTATWDPSPTQAKESPVAAGEAGPDWFPEGQEEDGGLCP---PLNQSSPTSKEGG- 400 PPSP A P P A +P +G G GG P P SS S G Sbjct: 931 PPSPVPAPPPPPPPTASPTPDKSGSPGKK--TSKTSSPGGKKPPPTPQRNSSIKSSSGAE 988 Query: 401 ----------------TLPAPVGSPE-----DPSDPPQPYRLADDYTPAPAAFQGLSLSS 439 T PA GSP P+ PP+P +L P Q +S+ Sbjct: 989 HPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSA 1048 Query: 440 HMSLLHSRNSCKTLKCP 456 +L R ++ P Sbjct: 1049 KAPVLSGRGKDSVVEFP 1065 >gi|12707580 paired-like homeobox 2b [Homo sapiens] Length = 314 Score = 66.2 bits (160), Expect = 4e-10 Identities = 68/230 (29%), Positives = 101/230 (43%), Gaps = 22/230 (9%) Query: 1983 GGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQNT 2042 GG E + +R+RTT QL+ L R + + P + ++ ++ L + VQVWFQN Sbjct: 90 GGLNEKRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNR 149 Query: 2043 RARERKGQFRSTPGGVPSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAFPY 2102 RA+ RK + A A A+ K N GK D + R+ +EA + Sbjct: 150 RAKFRK---------------QERAAAAAAAAAK-NGSSGKKSD-SSRDDESKEAKSTD- 191 Query: 2103 PTATLASGPQPFLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPK--ASPESEACSLS 2160 P +T GP P P A P P P EP K A+ + A + + Sbjct: 192 PDSTGGPGPNPNPTPSCGANGGGGGGPSPAGAPGAAGPGGPGGEPGKGGAAAAAAAAAAA 251 Query: 2161 AGDLSDSSASSLAEPESPGAGGTSGGPGGGTGVPDGMGQRRYRTQMSSLQ 2210 A + ++A LA PG G + GPG T +PD +G + + +SSLQ Sbjct: 252 AAAAAAAAAGGLAAAGGPGQ-GWAPGPGPITSIPDSLG-GPFASVLSSLQ 299 Score = 48.5 bits (114), Expect = 9e-05 Identities = 31/87 (35%), Positives = 45/87 (51%), Gaps = 6/87 (6%) Query: 2192 GVPDGMGQRRYRTQMSSLQLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNAR 2251 G+ + QRR RT +S QLK ++ + P + E L +I L + +QVWFQN R Sbjct: 91 GLNEKRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRR 150 Query: 2252 AKEKKAKLQGTAA------GSTGGSSE 2272 AK +K + AA GS+G S+ Sbjct: 151 AKFRKQERAAAAAAAAAKNGSSGKKSD 177 Score = 41.6 bits (96), Expect = 0.011 Identities = 29/83 (34%), Positives = 36/83 (43%), Gaps = 3/83 (3%) Query: 1729 RRFSRTKFTEFQTQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARKN- 1787 +R RT FT Q + L+ F + YP E LA + L V VWFQN R K RK Sbjct: 98 QRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFRKQE 157 Query: 1788 --ACEGGSMPTGGGTGGASGCRR 1808 A + G +G S R Sbjct: 158 RAAAAAAAAAKNGSSGKKSDSSR 180 >gi|169881277 PROP paired-like homeobox 1 [Homo sapiens] Length = 226 Score = 65.9 bits (159), Expect = 5e-10 Identities = 60/206 (29%), Positives = 86/206 (41%), Gaps = 10/206 (4%) Query: 2152 PESEACSLSAGDLSDSSASSLAEPESPGAGGTSGGPGGGT-GVPDGMGQRRYRTQMSSLQ 2210 PE + + DSSA G G + P GG G P +RR+RT S +Q Sbjct: 23 PERHPATGTPTTTVDSSAPPCRRLPGAGGGRSRFSPQGGQRGRPHS--RRRHRTTFSPVQ 80 Query: 2211 LKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAK---LQGTAAGST 2267 L+ +++ + + P + E L + GL + IQVWFQN RAK++K + LQ A S Sbjct: 81 LEQLESAFGRNQYPDIWARESLARDTGLSEARIQVWFQNRRAKQRKQERSLLQPLAHLSP 140 Query: 2268 GGSSEGLLAAQRTDCPYCDVKYDFYVSCRGHLFSRQHLAKLKEAVRAQLKSESKCYDLAP 2327 S L + T CPY V+C H +S H + + + D P Sbjct: 141 AAFSSFL--PESTACPYSYAAPPPPVTCFPHPYS--HALPSQPSTGGAFALSHQSEDWYP 196 Query: 2328 APEAPPALKAPPATTPASMPLGAAPT 2353 PA P P +PL P+ Sbjct: 197 TLHPAPAGHLPCPPPPPMLPLSLEPS 222 Score = 60.1 bits (144), Expect = 3e-08 Identities = 62/206 (30%), Positives = 83/206 (40%), Gaps = 32/206 (15%) Query: 1948 ERNPLVAA---TSPMPGPPLKRKHEDGSLSPTGSEAGGGGEGEPPRDKRLRTTILPEQLE 2004 ER+P T PP +R G S GG G P +R RTT P QLE Sbjct: 24 ERHPATGTPTTTVDSSAPPCRRLPGAGGGRSRFSPQGGQ-RGRPHSRRRHRTTFSPVQLE 82 Query: 2005 ILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQNTRARERKGQFRSTPGGVPSPAVK 2064 L + ++ P + ++ + GL + +QVWFQN RA++RK Q RS ++ Sbjct: 83 QLESAFGRNQYPDIWARESLARDTGLSEARIQVWFQNRRAKQRK-QERS--------LLQ 133 Query: 2065 PPATATPASLPKFNLLLGKVDDGTGREAPKREAPAFPYP-TATLASGPQ----------- 2112 P A +PA+ F L AP FP+P + L S P Sbjct: 134 PLAHLSPAAFSSF--LPESTACPYSYAAPPPPVTCFPHPYSHALPSQPSTGGAFALSHQS 191 Query: 2113 ----PFLPPGKEATTPTPEPPLPLLP 2134 P L P P P PP P+LP Sbjct: 192 EDWYPTLHPAPAGHLPCPPPP-PMLP 216 Score = 48.5 bits (114), Expect = 9e-05 Identities = 39/121 (32%), Positives = 49/121 (40%), Gaps = 8/121 (6%) Query: 1669 KPPDGSLDSPV-PHLGPPFLVPEPEAGGTRAPEER--SRAGGHWPIEEEESSRGNLPPLV 1725 KP G + S + P P P + P R GG + RG Sbjct: 11 KPKKGRVGSNLLPERHPATGTPTTTVDSSAPPCRRLPGAGGGRSRFSPQGGQRGR----- 65 Query: 1726 PAGRRFSRTKFTEFQTQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKAR 1785 P RR RT F+ Q + L+S F + YP E LA GL+ + VWFQN R K R Sbjct: 66 PHSRRRHRTTFSPVQLEQLESAFGRNQYPDIWARESLARDTGLSEARIQVWFQNRRAKQR 125 Query: 1786 K 1786 K Sbjct: 126 K 126 >gi|156416026 zinc finger protein 219 [Homo sapiens] Length = 722 Score = 65.5 bits (158), Expect = 7e-10 Identities = 107/431 (24%), Positives = 147/431 (34%), Gaps = 105/431 (24%) Query: 1517 PAPVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPSSPPDPLPNEAARTAAKA 1576 P L+ +A PPP PQP +PP E P S P P P Sbjct: 215 PERPLAATSAAPPPQPQP-----------QPPPQPE-----PRSVPQPEPEP-------- 250 Query: 1577 LLENFGFELVIQYNEGKQAVPPPPTPPPPEALGGGDKLACGACGKLFSNMLILKTHEEHV 1636 E ++ P P P PE + C CG+ F+ LK H Sbjct: 251 --------------EPEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKH 296 Query: 1637 HRRF---LPFEALSRYAAQFRKSYDSLYP----PLAEP---------PKPPDGSLDSPVP 1680 F P F K++ ++ PL P P+PPD L + P Sbjct: 297 KASFDHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAPGPASGPARAPQPPDLGLLAYEP 356 Query: 1681 HLGPPFLV-PEPEAGGTRAPEE-----RSRAGGHWPIEEEES-----SRGNLPPL---VP 1726 LGP L+ P P R P RAG P E S G PL +P Sbjct: 357 -LGPALLLAPAPTPAERREPPSLLGYLSLRAGEGRPNGEGAEPGPGRSFGGFRPLSSALP 415 Query: 1727 AGRRFSRTKFTEFQTQALQSFFET-----------SAYPKDGE-VERLASLLGLASRVVV 1774 A R R + E + + +++ ET S +P+ GE AS G +R Sbjct: 416 ARARRHRAEEPEEEEEVVEAEEETWARGRSLGSLASLHPRPGEGPGHSASAAGAQARSTA 475 Query: 1775 VWFQNARQKARKNACEGGSMPTGGGTGGASGCRRCHATFSCVFELVRHLKKCYDDQTLE- 1833 +N GG+ P GG C C +F L HL+ ++ + Sbjct: 476 TQEEN-------GLLVGGTRPEGGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKC 528 Query: 1834 --EEEEEAERGEEEEEVEEEEVEEEQGLEPPAGPEGPLPEPPDGEELSQAEATKAGGKEP 1891 + + G + ++ E+ G AGP GP PEPP + G P Sbjct: 529 PHCDYAGTQSGSLKYHLQRHHREQRSG----AGP-GPPPEPPPPSQ---------RGSAP 574 Query: 1892 EEKATPSPSPA 1902 + A PSP PA Sbjct: 575 QSGAKPSPQPA 585 Score = 57.8 bits (138), Expect = 1e-07 Identities = 114/487 (23%), Positives = 158/487 (32%), Gaps = 114/487 (23%) Query: 1236 PEPPLASVEVPDKPSGSPGQPPSPAPSPVPEPDAQAEDVAPPPTMAEEEEGTTGELRSAE 1295 PE PLA+ P P PP P P VP+P+ + E E E T Sbjct: 215 PERPLAATSAAPPPQPQPQPPPQPEPRSVPQPEPEPE---------PEREAT------PT 259 Query: 1296 PAPADSRHPLTYRKTTNFALDKFLDPARP-YKCTVCKESFTQKNILLVHYNSVSHLHKMK 1354 PAPA P PA P ++C VC +SFTQ L H + Sbjct: 260 PAPAAPEEP----------------PAPPEFRCQVCGQSFTQSWFLKGHM-------RKH 296 Query: 1355 KAAIDPSAPARGEAGAPPTTTAATDKPFKCTVCRVSYNQSSTLEIHMRSVLHQTRSRGTK 1414 KA+ D + C VC + + L+ HM+ +H ++ + Sbjct: 297 KASFDHA----------------------CPVCGRCFKEPWFLKNHMK--VHASKLGPLR 332 Query: 1415 TDSKIEGPERSQEEPKEGETEGEVGTEKKGPDTSGFISGLPFLSPPPPPLDLHRFPAPLF 1474 GP R+ + P G + E GP L+P P P + R P L Sbjct: 333 APGPASGPARAPQPP----DLGLLAYEPLGPAL--------LLAPAPTPAE-RREPPSLL 379 Query: 1475 TPPVLPPFPLVPESLLKLQQQQLLLPFYLHDLKVGPKLTLAGPAPVLS-LPAATPPPPPQ 1533 L P + GP + G P+ S LPA + Sbjct: 380 GYLSLRAGEGRPNG---------------EGAEPGPGRSFGGFRPLSSALPARARRHRAE 424 Query: 1534 PPKAELAEREWERPPMAKEGNEAGPSSPPDPLPNEAARTAAKALLENFGFELVIQYNEGK 1593 P+ E E E A+ G G + P P E +A A G + + + Sbjct: 425 EPEEEEEVVEAEEETWAR-GRSLGSLASLHPRPGEGPGHSASAA----GAQARSTATQEE 479 Query: 1594 QAVPPPPTPPPPEALGGGDKLACGACGKLFSNMLILKTHEEHVHRRFLPFE--------- 1644 + T PE G C CGK F + LK H VH P++ Sbjct: 480 NGLLVGGT--RPEGGRGATGKDCPFCGKSFRSAHHLKVH-LRVHTGERPYKCPHCDYAGT 536 Query: 1645 ---ALSRYAAQFRKSYDSLYPPLAEPPKPPDGSLDSPVPHLG-PPFLVPEPEAGGTRAPE 1700 +L + + + S P PP+PP S P G P P G +P Sbjct: 537 QSGSLKYHLQRHHREQRSGAGP-GPPPEPPPPSQRGSAPQSGAKPSPQPATWVEGASSPR 595 Query: 1701 ERSRAGG 1707 S G Sbjct: 596 PPSSGAG 602 Score = 52.4 bits (124), Expect = 6e-06 Identities = 111/510 (21%), Positives = 156/510 (30%), Gaps = 122/510 (23%) Query: 1788 ACEGGSMPTGGGTGGASGCRRCHATFSCVFELVRHLK------KCYDDQTLEEEEEEAER 1841 A EG + P + A C C F E RHL KC +EEE Sbjct: 148 ATEGLARPQAPSSS-AFRCPYCKGKFRTSAERERHLHILHRPWKCGLCSFGSSQEEELLH 206 Query: 1842 GEEEEEVEEEEVEEEQGLEPPAGPEGPLPEPPDGEELSQAEATKAGGKEPEEKATPSPSP 1901 E PP P+ P P+ + Q E EPE +ATP+P+P Sbjct: 207 HSLTAHGAPERPLAATSAAPPPQPQPQPPPQPEPRSVPQPEPEP----EPEREATPTPAP 262 Query: 1902 A--------------------------------------HTCDQCAISFSSQDLLTSHRR 1923 A H C C F L +H + Sbjct: 263 AAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMK 322 Query: 1924 LHFL---------PSLQPSAPPQLLDLPLLVFGERNP-LVAATSPMPGPPLKRKHEDGSL 1973 +H P+ P+ PQ DL LL + P L+ A +P P + G L Sbjct: 323 VHASKLGPLRAPGPASGPARAPQPPDLGLLAYEPLGPALLLAPAPTPAERREPPSLLGYL 382 Query: 1974 SPTGSEAGGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKR 2033 S E GEG P R P + + R + EE + + Sbjct: 383 SLRAGEGRPNGEGAEPGPGRSFGGFRPLSSAL-------PARARRHRAEEPEEEEEVVEA 435 Query: 2034 VVQVWFQNTRARERKGQFRSTPGGVP--SPAVKPPATATPASLPKFNLLLGKVDDGTGRE 2091 + W + R+ PG P S + + A+ + LL+G GR Sbjct: 436 EEETWARG-RSLGSLASLHPRPGEGPGHSASAAGAQARSTATQEENGLLVGGTRPEGGRG 494 Query: 2092 APKREAP--AFPYPTA-------TLASGPQPFLPP----------------------GKE 2120 A ++ P + +A + +G +P+ P + Sbjct: 495 ATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRS 554 Query: 2121 ATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPES----EACSLSAGDLSDSSASSLAEPE 2176 P P P PPPP P+ K SP+ E S S + S +P Sbjct: 555 GAGPGPPPE----PPPPSQRGSAPQSGAKPSPQPATWVEGASSPRPPSSGAGPGSRRKPA 610 Query: 2177 SP------GAGGTS--------GGPGGGTG 2192 SP G GG + GPGG G Sbjct: 611 SPGRTLRNGRGGEAEPLDLSLRAGPGGEAG 640 Score = 46.6 bits (109), Expect = 3e-04 Identities = 99/420 (23%), Positives = 145/420 (34%), Gaps = 80/420 (19%) Query: 398 EGGTLPAPVGSPEDPSDPPQPYRL-ADDYTPAPAAFQGLSLSSHMSLLHSRNSCKTLKCP 456 EG AP G PS P L Y+ PA G +S SR + CP Sbjct: 2 EGSRPRAPSGHLA-PSPPAFDGELDLQRYSNGPAVSAGSLGMGAVSWSESRAGERRFPCP 60 Query: 457 KCNWHYKYQQTLDVHMREKHPESNS-HCSYCSAGGAHPRLARGESYNCGYKPYRCDVCNY 515 C +++ L +H+R HP + + C +C A L R S+ ++P R Sbjct: 61 VCGKRFRFNSILALHLR-AHPGAQAFQCPHCGHRAAQRALLR--SHLRTHQPER----PR 113 Query: 516 STTTKGNLSIHMQSDKHLANLQGFQAGPGGQGSPPEASLPPSAGDKEPKTKSSWQCKVC- 574 S + L + ++ A L ++ G Q +P L + + S+++C C Sbjct: 114 SPAARLLLELEERALLREARLGRARSSGGMQATPATEGL----ARPQAPSSSAFRCPYCK 169 Query: 575 -SYETNISRNLRIHMTSEKHMQNVLMLHQGLPLGLPPGLMGPGPPPPPGATPTSPPELFQ 633 + T+ R +H +LH+ GL + +S E Sbjct: 170 GKFRTSAERERHLH-----------ILHRPWKCGL-------------CSFGSSQEEELL 205 Query: 634 YFGPQALGQPQTPLAGPGLRPDKPLEAQLLLNGFHHVGAPARKFPTSAPGSLSPDAHLPP 693 + A G P+ PLA P + Q P + P S P P+ P Sbjct: 206 HHSLTAHGAPERPLAATSAAPPPQPQPQ----------PPPQPEPRSVP---QPEPEPEP 252 Query: 694 SQLLGSSSDSLPTSPP--PDDSLSLKVFRCLVCQAFSTDSLELLLYHCSIGRSLPEAEWK 751 + ++ PT P P++ + FRC VC T S L H K Sbjct: 253 ER------EATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSW-FLKGHMR----------K 295 Query: 752 EVAGDTHRCKLCCYGTQLKANFQLHLKTDKHAQKYQLAAHLREGGGAMG---TPSPASLG 808 A H C +C G K + L HA K LR G A G P P LG Sbjct: 296 HKASFDHACPVC--GRCFKEPWFLKNHMKVHASK---LGPLRAPGPASGPARAPQPPDLG 350 Score = 42.0 bits (97), Expect = 0.008 Identities = 31/118 (26%), Positives = 44/118 (37%), Gaps = 33/118 (27%) Query: 455 CPKCNWHYKYQQTLDVHMREKHPESNSHCSYCSAGGAHPRLARGESYNCGYKPYRCDVCN 514 CP C ++ L VH+R + G +PY+C C+ Sbjct: 500 CPFCGKSFRSAHHLKVHLR---------------------------VHTGERPYKCPHCD 532 Query: 515 YSTTTKGNLSIHMQSDKHLANLQGFQAGPGGQGSPPEAS---LPPSAGDKEPKTKSSW 569 Y+ T G+L H+Q H G AGPG PP S P +G K ++W Sbjct: 533 YAGTQSGSLKYHLQR-HHREQRSG--AGPGPPPEPPPPSQRGSAPQSGAKPSPQPATW 587 Score = 38.9 bits (89), Expect = 0.070 Identities = 46/206 (22%), Positives = 71/206 (34%), Gaps = 26/206 (12%) Query: 438 SSHMSLLHSR--NSCKTLKCPKCNWHYKYQQTLDVHMREKHPESNSHCSYCSAGGAHPRL 495 S+H +H R + KCP C++ +L H++ H E S P Sbjct: 509 SAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSGAGPGPPPEPPPPS 568 Query: 496 ARGESYNCGYKPYRCDVCNYSTTTKGNLSIHMQSD--------KHLANLQGFQAGPGGQG 547 RG + G KP +T +G S S K + + + G GG+ Sbjct: 569 QRGSAPQSGAKPSP----QPATWVEGASSPRPPSSGAGPGSRRKPASPGRTLRNGRGGEA 624 Query: 548 SPPEASLPPSAGDKEPKTKSSWQCKVCSYETNISRNLRIHMTSEKHMQNVLMLHQGLPLG 607 P + SL G + + +C C + T + +H+ + H G Sbjct: 625 EPLDLSLRAGPGGEAGPGGALHRCLFCPFATGAPELMALHLQ---------VHHSRRARG 675 Query: 608 LPPGLMGPGPP---PPPGATPTSPPE 630 P PP P G TP SP + Sbjct: 676 RRPPQADASPPYARVPSGETPPSPSQ 701 Score = 37.7 bits (86), Expect = 0.15 Identities = 51/219 (23%), Positives = 79/219 (36%), Gaps = 55/219 (25%) Query: 473 REKHPESNS-HCSYCSAGGAHPRLARGESYNCGYKPYRCDVCNYSTTTKGNLSIHMQSDK 531 R + P S++ C YC G R + ++P++C +C++ ++ + L +H Sbjct: 154 RPQAPSSSAFRCPYCK-GKFRTSAERERHLHILHRPWKCGLCSFGSSQEEEL-LHHSLTA 211 Query: 532 HLAN---LQGFQAGPGGQGSP-------------------PEASLPPS---AGDKEPKTK 566 H A L A P Q P PE P+ A +EP Sbjct: 212 HGAPERPLAATSAAPPPQPQPQPPPQPEPRSVPQPEPEPEPEREATPTPAPAAPEEPPAP 271 Query: 567 SSWQCKVCSYETNISRNLRIHMTSEK------------------HMQNVLMLHQGLPLGL 608 ++C+VC S L+ HM K ++N + +H LG Sbjct: 272 PEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHAS-KLG- 329 Query: 609 PPGLMGPGPPPPPGATPTSPPEL----FQYFGPQALGQP 643 L PGP P P PP+L ++ GP L P Sbjct: 330 --PLRAPGPASGPARAP-QPPDLGLLAYEPLGPALLLAP 365 Score = 34.7 bits (78), Expect = 1.3 Identities = 44/161 (27%), Positives = 55/161 (34%), Gaps = 12/161 (7%) Query: 2405 AGPGRPLPQRPMPDQTNTSTAGTTDPVPGPPTEPLGDKVSSERKPV--AGPTSSSNDALK 2462 AGPG P P+ P P Q ++ P P P T G SS R P AGP S A Sbjct: 556 AGPGPP-PEPPPPSQRGSAPQSGAKPSPQPATWVEG--ASSPRPPSSGAGPGSRRKPASP 612 Query: 2463 NLKALKTTVPALLGGQFLPFPLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNPMI 2522 T+ GG+ P L G A G L F L ++ + Sbjct: 613 G-----RTLRNGRGGEAEPLDLSLRAGPGGEAGPGGALHRCLFCPFATGAPELMALHLQV 667 Query: 2523 --PQTLIGLLPNALLQPPPQPPEPTATAPPKPPELPAPGEG 2561 + G P PP P+ PP P + G G Sbjct: 668 HHSRRARGRRPPQADASPPYARVPSGETPPSPSQEGEEGSG 708 Score = 32.7 bits (73), Expect = 5.0 Identities = 45/188 (23%), Positives = 65/188 (34%), Gaps = 38/188 (20%) Query: 569 WQCKVCSYETNISRNLRIHMTSEKHMQNVLMLHQGLPLGLPPGLMGPGPPPPPGATPTSP 628 ++C C Y S +L+ H+ Q G GP PPP P S Sbjct: 526 YKCPHCDYAGTQSGSLKYHLQRHHREQR----------------SGAGPGPPPEPPPPSQ 569 Query: 629 PELFQYFGPQALGQPQTPLAGPGLRPDKPLEAQLLLNGFHHVGAPARKFPTSAPGSLSPD 688 G + QP T + G P P G +R+ P S PG + Sbjct: 570 RGSAPQSGAKPSPQPATWVEGAS-SPRPPSSG---------AGPGSRRKPAS-PGRTLRN 618 Query: 689 AHLPPSQLLGSSSDSLPTSPPPDDSLSLKVFRCLVCQAFSTDSLELLLYHCSI------- 741 ++ L SL P + + RCL C F+T + EL+ H + Sbjct: 619 GRGGEAEPLDL---SLRAGPGGEAGPGGALHRCLFC-PFATGAPELMALHLQVHHSRRAR 674 Query: 742 GRSLPEAE 749 GR P+A+ Sbjct: 675 GRRPPQAD 682 >gi|156415998 zinc finger protein 219 [Homo sapiens] Length = 722 Score = 65.5 bits (158), Expect = 7e-10 Identities = 107/431 (24%), Positives = 147/431 (34%), Gaps = 105/431 (24%) Query: 1517 PAPVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPSSPPDPLPNEAARTAAKA 1576 P L+ +A PPP PQP +PP E P S P P P Sbjct: 215 PERPLAATSAAPPPQPQP-----------QPPPQPE-----PRSVPQPEPEP-------- 250 Query: 1577 LLENFGFELVIQYNEGKQAVPPPPTPPPPEALGGGDKLACGACGKLFSNMLILKTHEEHV 1636 E ++ P P P PE + C CG+ F+ LK H Sbjct: 251 --------------EPEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKH 296 Query: 1637 HRRF---LPFEALSRYAAQFRKSYDSLYP----PLAEP---------PKPPDGSLDSPVP 1680 F P F K++ ++ PL P P+PPD L + P Sbjct: 297 KASFDHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAPGPASGPARAPQPPDLGLLAYEP 356 Query: 1681 HLGPPFLV-PEPEAGGTRAPEE-----RSRAGGHWPIEEEES-----SRGNLPPL---VP 1726 LGP L+ P P R P RAG P E S G PL +P Sbjct: 357 -LGPALLLAPAPTPAERREPPSLLGYLSLRAGEGRPNGEGAEPGPGRSFGGFRPLSSALP 415 Query: 1727 AGRRFSRTKFTEFQTQALQSFFET-----------SAYPKDGE-VERLASLLGLASRVVV 1774 A R R + E + + +++ ET S +P+ GE AS G +R Sbjct: 416 ARARRHRAEEPEEEEEVVEAEEETWARGRSLGSLASLHPRPGEGPGHSASAAGAQARSTA 475 Query: 1775 VWFQNARQKARKNACEGGSMPTGGGTGGASGCRRCHATFSCVFELVRHLKKCYDDQTLE- 1833 +N GG+ P GG C C +F L HL+ ++ + Sbjct: 476 TQEEN-------GLLVGGTRPEGGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKC 528 Query: 1834 --EEEEEAERGEEEEEVEEEEVEEEQGLEPPAGPEGPLPEPPDGEELSQAEATKAGGKEP 1891 + + G + ++ E+ G AGP GP PEPP + G P Sbjct: 529 PHCDYAGTQSGSLKYHLQRHHREQRSG----AGP-GPPPEPPPPSQ---------RGSAP 574 Query: 1892 EEKATPSPSPA 1902 + A PSP PA Sbjct: 575 QSGAKPSPQPA 585 Score = 57.8 bits (138), Expect = 1e-07 Identities = 114/487 (23%), Positives = 158/487 (32%), Gaps = 114/487 (23%) Query: 1236 PEPPLASVEVPDKPSGSPGQPPSPAPSPVPEPDAQAEDVAPPPTMAEEEEGTTGELRSAE 1295 PE PLA+ P P PP P P VP+P+ + E E E T Sbjct: 215 PERPLAATSAAPPPQPQPQPPPQPEPRSVPQPEPEPE---------PEREAT------PT 259 Query: 1296 PAPADSRHPLTYRKTTNFALDKFLDPARP-YKCTVCKESFTQKNILLVHYNSVSHLHKMK 1354 PAPA P PA P ++C VC +SFTQ L H + Sbjct: 260 PAPAAPEEP----------------PAPPEFRCQVCGQSFTQSWFLKGHM-------RKH 296 Query: 1355 KAAIDPSAPARGEAGAPPTTTAATDKPFKCTVCRVSYNQSSTLEIHMRSVLHQTRSRGTK 1414 KA+ D + C VC + + L+ HM+ +H ++ + Sbjct: 297 KASFDHA----------------------CPVCGRCFKEPWFLKNHMK--VHASKLGPLR 332 Query: 1415 TDSKIEGPERSQEEPKEGETEGEVGTEKKGPDTSGFISGLPFLSPPPPPLDLHRFPAPLF 1474 GP R+ + P G + E GP L+P P P + R P L Sbjct: 333 APGPASGPARAPQPP----DLGLLAYEPLGPAL--------LLAPAPTPAE-RREPPSLL 379 Query: 1475 TPPVLPPFPLVPESLLKLQQQQLLLPFYLHDLKVGPKLTLAGPAPVLS-LPAATPPPPPQ 1533 L P + GP + G P+ S LPA + Sbjct: 380 GYLSLRAGEGRPNG---------------EGAEPGPGRSFGGFRPLSSALPARARRHRAE 424 Query: 1534 PPKAELAEREWERPPMAKEGNEAGPSSPPDPLPNEAARTAAKALLENFGFELVIQYNEGK 1593 P+ E E E A+ G G + P P E +A A G + + + Sbjct: 425 EPEEEEEVVEAEEETWAR-GRSLGSLASLHPRPGEGPGHSASAA----GAQARSTATQEE 479 Query: 1594 QAVPPPPTPPPPEALGGGDKLACGACGKLFSNMLILKTHEEHVHRRFLPFE--------- 1644 + T PE G C CGK F + LK H VH P++ Sbjct: 480 NGLLVGGT--RPEGGRGATGKDCPFCGKSFRSAHHLKVH-LRVHTGERPYKCPHCDYAGT 536 Query: 1645 ---ALSRYAAQFRKSYDSLYPPLAEPPKPPDGSLDSPVPHLG-PPFLVPEPEAGGTRAPE 1700 +L + + + S P PP+PP S P G P P G +P Sbjct: 537 QSGSLKYHLQRHHREQRSGAGP-GPPPEPPPPSQRGSAPQSGAKPSPQPATWVEGASSPR 595 Query: 1701 ERSRAGG 1707 S G Sbjct: 596 PPSSGAG 602 Score = 52.4 bits (124), Expect = 6e-06 Identities = 111/510 (21%), Positives = 156/510 (30%), Gaps = 122/510 (23%) Query: 1788 ACEGGSMPTGGGTGGASGCRRCHATFSCVFELVRHLK------KCYDDQTLEEEEEEAER 1841 A EG + P + A C C F E RHL KC +EEE Sbjct: 148 ATEGLARPQAPSSS-AFRCPYCKGKFRTSAERERHLHILHRPWKCGLCSFGSSQEEELLH 206 Query: 1842 GEEEEEVEEEEVEEEQGLEPPAGPEGPLPEPPDGEELSQAEATKAGGKEPEEKATPSPSP 1901 E PP P+ P P+ + Q E EPE +ATP+P+P Sbjct: 207 HSLTAHGAPERPLAATSAAPPPQPQPQPPPQPEPRSVPQPEPEP----EPEREATPTPAP 262 Query: 1902 A--------------------------------------HTCDQCAISFSSQDLLTSHRR 1923 A H C C F L +H + Sbjct: 263 AAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMK 322 Query: 1924 LHFL---------PSLQPSAPPQLLDLPLLVFGERNP-LVAATSPMPGPPLKRKHEDGSL 1973 +H P+ P+ PQ DL LL + P L+ A +P P + G L Sbjct: 323 VHASKLGPLRAPGPASGPARAPQPPDLGLLAYEPLGPALLLAPAPTPAERREPPSLLGYL 382 Query: 1974 SPTGSEAGGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKR 2033 S E GEG P R P + + R + EE + + Sbjct: 383 SLRAGEGRPNGEGAEPGPGRSFGGFRPLSSAL-------PARARRHRAEEPEEEEEVVEA 435 Query: 2034 VVQVWFQNTRARERKGQFRSTPGGVP--SPAVKPPATATPASLPKFNLLLGKVDDGTGRE 2091 + W + R+ PG P S + + A+ + LL+G GR Sbjct: 436 EEETWARG-RSLGSLASLHPRPGEGPGHSASAAGAQARSTATQEENGLLVGGTRPEGGRG 494 Query: 2092 APKREAP--AFPYPTA-------TLASGPQPFLPP----------------------GKE 2120 A ++ P + +A + +G +P+ P + Sbjct: 495 ATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRS 554 Query: 2121 ATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPES----EACSLSAGDLSDSSASSLAEPE 2176 P P P PPPP P+ K SP+ E S S + S +P Sbjct: 555 GAGPGPPPE----PPPPSQRGSAPQSGAKPSPQPATWVEGASSPRPPSSGAGPGSRRKPA 610 Query: 2177 SP------GAGGTS--------GGPGGGTG 2192 SP G GG + GPGG G Sbjct: 611 SPGRTLRNGRGGEAEPLDLSLRAGPGGEAG 640 Score = 46.6 bits (109), Expect = 3e-04 Identities = 99/420 (23%), Positives = 145/420 (34%), Gaps = 80/420 (19%) Query: 398 EGGTLPAPVGSPEDPSDPPQPYRL-ADDYTPAPAAFQGLSLSSHMSLLHSRNSCKTLKCP 456 EG AP G PS P L Y+ PA G +S SR + CP Sbjct: 2 EGSRPRAPSGHLA-PSPPAFDGELDLQRYSNGPAVSAGSLGMGAVSWSESRAGERRFPCP 60 Query: 457 KCNWHYKYQQTLDVHMREKHPESNS-HCSYCSAGGAHPRLARGESYNCGYKPYRCDVCNY 515 C +++ L +H+R HP + + C +C A L R S+ ++P R Sbjct: 61 VCGKRFRFNSILALHLR-AHPGAQAFQCPHCGHRAAQRALLR--SHLRTHQPER----PR 113 Query: 516 STTTKGNLSIHMQSDKHLANLQGFQAGPGGQGSPPEASLPPSAGDKEPKTKSSWQCKVC- 574 S + L + ++ A L ++ G Q +P L + + S+++C C Sbjct: 114 SPAARLLLELEERALLREARLGRARSSGGMQATPATEGL----ARPQAPSSSAFRCPYCK 169 Query: 575 -SYETNISRNLRIHMTSEKHMQNVLMLHQGLPLGLPPGLMGPGPPPPPGATPTSPPELFQ 633 + T+ R +H +LH+ GL + +S E Sbjct: 170 GKFRTSAERERHLH-----------ILHRPWKCGL-------------CSFGSSQEEELL 205 Query: 634 YFGPQALGQPQTPLAGPGLRPDKPLEAQLLLNGFHHVGAPARKFPTSAPGSLSPDAHLPP 693 + A G P+ PLA P + Q P + P S P P+ P Sbjct: 206 HHSLTAHGAPERPLAATSAAPPPQPQPQ----------PPPQPEPRSVP---QPEPEPEP 252 Query: 694 SQLLGSSSDSLPTSPP--PDDSLSLKVFRCLVCQAFSTDSLELLLYHCSIGRSLPEAEWK 751 + ++ PT P P++ + FRC VC T S L H K Sbjct: 253 ER------EATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSW-FLKGHMR----------K 295 Query: 752 EVAGDTHRCKLCCYGTQLKANFQLHLKTDKHAQKYQLAAHLREGGGAMG---TPSPASLG 808 A H C +C G K + L HA K LR G A G P P LG Sbjct: 296 HKASFDHACPVC--GRCFKEPWFLKNHMKVHASK---LGPLRAPGPASGPARAPQPPDLG 350 Score = 42.0 bits (97), Expect = 0.008 Identities = 31/118 (26%), Positives = 44/118 (37%), Gaps = 33/118 (27%) Query: 455 CPKCNWHYKYQQTLDVHMREKHPESNSHCSYCSAGGAHPRLARGESYNCGYKPYRCDVCN 514 CP C ++ L VH+R + G +PY+C C+ Sbjct: 500 CPFCGKSFRSAHHLKVHLR---------------------------VHTGERPYKCPHCD 532 Query: 515 YSTTTKGNLSIHMQSDKHLANLQGFQAGPGGQGSPPEAS---LPPSAGDKEPKTKSSW 569 Y+ T G+L H+Q H G AGPG PP S P +G K ++W Sbjct: 533 YAGTQSGSLKYHLQR-HHREQRSG--AGPGPPPEPPPPSQRGSAPQSGAKPSPQPATW 587 Score = 38.9 bits (89), Expect = 0.070 Identities = 46/206 (22%), Positives = 71/206 (34%), Gaps = 26/206 (12%) Query: 438 SSHMSLLHSR--NSCKTLKCPKCNWHYKYQQTLDVHMREKHPESNSHCSYCSAGGAHPRL 495 S+H +H R + KCP C++ +L H++ H E S P Sbjct: 509 SAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSGAGPGPPPEPPPPS 568 Query: 496 ARGESYNCGYKPYRCDVCNYSTTTKGNLSIHMQSD--------KHLANLQGFQAGPGGQG 547 RG + G KP +T +G S S K + + + G GG+ Sbjct: 569 QRGSAPQSGAKPSP----QPATWVEGASSPRPPSSGAGPGSRRKPASPGRTLRNGRGGEA 624 Query: 548 SPPEASLPPSAGDKEPKTKSSWQCKVCSYETNISRNLRIHMTSEKHMQNVLMLHQGLPLG 607 P + SL G + + +C C + T + +H+ + H G Sbjct: 625 EPLDLSLRAGPGGEAGPGGALHRCLFCPFATGAPELMALHLQ---------VHHSRRARG 675 Query: 608 LPPGLMGPGPP---PPPGATPTSPPE 630 P PP P G TP SP + Sbjct: 676 RRPPQADASPPYARVPSGETPPSPSQ 701 Score = 37.7 bits (86), Expect = 0.15 Identities = 51/219 (23%), Positives = 79/219 (36%), Gaps = 55/219 (25%) Query: 473 REKHPESNS-HCSYCSAGGAHPRLARGESYNCGYKPYRCDVCNYSTTTKGNLSIHMQSDK 531 R + P S++ C YC G R + ++P++C +C++ ++ + L +H Sbjct: 154 RPQAPSSSAFRCPYCK-GKFRTSAERERHLHILHRPWKCGLCSFGSSQEEEL-LHHSLTA 211 Query: 532 HLAN---LQGFQAGPGGQGSP-------------------PEASLPPS---AGDKEPKTK 566 H A L A P Q P PE P+ A +EP Sbjct: 212 HGAPERPLAATSAAPPPQPQPQPPPQPEPRSVPQPEPEPEPEREATPTPAPAAPEEPPAP 271 Query: 567 SSWQCKVCSYETNISRNLRIHMTSEK------------------HMQNVLMLHQGLPLGL 608 ++C+VC S L+ HM K ++N + +H LG Sbjct: 272 PEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHAS-KLG- 329 Query: 609 PPGLMGPGPPPPPGATPTSPPEL----FQYFGPQALGQP 643 L PGP P P PP+L ++ GP L P Sbjct: 330 --PLRAPGPASGPARAP-QPPDLGLLAYEPLGPALLLAP 365 Score = 34.7 bits (78), Expect = 1.3 Identities = 44/161 (27%), Positives = 55/161 (34%), Gaps = 12/161 (7%) Query: 2405 AGPGRPLPQRPMPDQTNTSTAGTTDPVPGPPTEPLGDKVSSERKPV--AGPTSSSNDALK 2462 AGPG P P+ P P Q ++ P P P T G SS R P AGP S A Sbjct: 556 AGPGPP-PEPPPPSQRGSAPQSGAKPSPQPATWVEG--ASSPRPPSSGAGPGSRRKPASP 612 Query: 2463 NLKALKTTVPALLGGQFLPFPLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNPMI 2522 T+ GG+ P L G A G L F L ++ + Sbjct: 613 G-----RTLRNGRGGEAEPLDLSLRAGPGGEAGPGGALHRCLFCPFATGAPELMALHLQV 667 Query: 2523 --PQTLIGLLPNALLQPPPQPPEPTATAPPKPPELPAPGEG 2561 + G P PP P+ PP P + G G Sbjct: 668 HHSRRARGRRPPQADASPPYARVPSGETPPSPSQEGEEGSG 708 Score = 32.7 bits (73), Expect = 5.0 Identities = 45/188 (23%), Positives = 65/188 (34%), Gaps = 38/188 (20%) Query: 569 WQCKVCSYETNISRNLRIHMTSEKHMQNVLMLHQGLPLGLPPGLMGPGPPPPPGATPTSP 628 ++C C Y S +L+ H+ Q G GP PPP P S Sbjct: 526 YKCPHCDYAGTQSGSLKYHLQRHHREQR----------------SGAGPGPPPEPPPPSQ 569 Query: 629 PELFQYFGPQALGQPQTPLAGPGLRPDKPLEAQLLLNGFHHVGAPARKFPTSAPGSLSPD 688 G + QP T + G P P G +R+ P S PG + Sbjct: 570 RGSAPQSGAKPSPQPATWVEGAS-SPRPPSSG---------AGPGSRRKPAS-PGRTLRN 618 Query: 689 AHLPPSQLLGSSSDSLPTSPPPDDSLSLKVFRCLVCQAFSTDSLELLLYHCSI------- 741 ++ L SL P + + RCL C F+T + EL+ H + Sbjct: 619 GRGGEAEPLDL---SLRAGPGGEAGPGGALHRCLFC-PFATGAPELMALHLQVHHSRRAR 674 Query: 742 GRSLPEAE 749 GR P+A+ Sbjct: 675 GRRPPQAD 682 >gi|156415996 zinc finger protein 219 [Homo sapiens] Length = 722 Score = 65.5 bits (158), Expect = 7e-10 Identities = 107/431 (24%), Positives = 147/431 (34%), Gaps = 105/431 (24%) Query: 1517 PAPVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPSSPPDPLPNEAARTAAKA 1576 P L+ +A PPP PQP +PP E P S P P P Sbjct: 215 PERPLAATSAAPPPQPQP-----------QPPPQPE-----PRSVPQPEPEP-------- 250 Query: 1577 LLENFGFELVIQYNEGKQAVPPPPTPPPPEALGGGDKLACGACGKLFSNMLILKTHEEHV 1636 E ++ P P P PE + C CG+ F+ LK H Sbjct: 251 --------------EPEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKH 296 Query: 1637 HRRF---LPFEALSRYAAQFRKSYDSLYP----PLAEP---------PKPPDGSLDSPVP 1680 F P F K++ ++ PL P P+PPD L + P Sbjct: 297 KASFDHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAPGPASGPARAPQPPDLGLLAYEP 356 Query: 1681 HLGPPFLV-PEPEAGGTRAPEE-----RSRAGGHWPIEEEES-----SRGNLPPL---VP 1726 LGP L+ P P R P RAG P E S G PL +P Sbjct: 357 -LGPALLLAPAPTPAERREPPSLLGYLSLRAGEGRPNGEGAEPGPGRSFGGFRPLSSALP 415 Query: 1727 AGRRFSRTKFTEFQTQALQSFFET-----------SAYPKDGE-VERLASLLGLASRVVV 1774 A R R + E + + +++ ET S +P+ GE AS G +R Sbjct: 416 ARARRHRAEEPEEEEEVVEAEEETWARGRSLGSLASLHPRPGEGPGHSASAAGAQARSTA 475 Query: 1775 VWFQNARQKARKNACEGGSMPTGGGTGGASGCRRCHATFSCVFELVRHLKKCYDDQTLE- 1833 +N GG+ P GG C C +F L HL+ ++ + Sbjct: 476 TQEEN-------GLLVGGTRPEGGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKC 528 Query: 1834 --EEEEEAERGEEEEEVEEEEVEEEQGLEPPAGPEGPLPEPPDGEELSQAEATKAGGKEP 1891 + + G + ++ E+ G AGP GP PEPP + G P Sbjct: 529 PHCDYAGTQSGSLKYHLQRHHREQRSG----AGP-GPPPEPPPPSQ---------RGSAP 574 Query: 1892 EEKATPSPSPA 1902 + A PSP PA Sbjct: 575 QSGAKPSPQPA 585 Score = 57.8 bits (138), Expect = 1e-07 Identities = 114/487 (23%), Positives = 158/487 (32%), Gaps = 114/487 (23%) Query: 1236 PEPPLASVEVPDKPSGSPGQPPSPAPSPVPEPDAQAEDVAPPPTMAEEEEGTTGELRSAE 1295 PE PLA+ P P PP P P VP+P+ + E E E T Sbjct: 215 PERPLAATSAAPPPQPQPQPPPQPEPRSVPQPEPEPE---------PEREAT------PT 259 Query: 1296 PAPADSRHPLTYRKTTNFALDKFLDPARP-YKCTVCKESFTQKNILLVHYNSVSHLHKMK 1354 PAPA P PA P ++C VC +SFTQ L H + Sbjct: 260 PAPAAPEEP----------------PAPPEFRCQVCGQSFTQSWFLKGHM-------RKH 296 Query: 1355 KAAIDPSAPARGEAGAPPTTTAATDKPFKCTVCRVSYNQSSTLEIHMRSVLHQTRSRGTK 1414 KA+ D + C VC + + L+ HM+ +H ++ + Sbjct: 297 KASFDHA----------------------CPVCGRCFKEPWFLKNHMK--VHASKLGPLR 332 Query: 1415 TDSKIEGPERSQEEPKEGETEGEVGTEKKGPDTSGFISGLPFLSPPPPPLDLHRFPAPLF 1474 GP R+ + P G + E GP L+P P P + R P L Sbjct: 333 APGPASGPARAPQPP----DLGLLAYEPLGPAL--------LLAPAPTPAE-RREPPSLL 379 Query: 1475 TPPVLPPFPLVPESLLKLQQQQLLLPFYLHDLKVGPKLTLAGPAPVLS-LPAATPPPPPQ 1533 L P + GP + G P+ S LPA + Sbjct: 380 GYLSLRAGEGRPNG---------------EGAEPGPGRSFGGFRPLSSALPARARRHRAE 424 Query: 1534 PPKAELAEREWERPPMAKEGNEAGPSSPPDPLPNEAARTAAKALLENFGFELVIQYNEGK 1593 P+ E E E A+ G G + P P E +A A G + + + Sbjct: 425 EPEEEEEVVEAEEETWAR-GRSLGSLASLHPRPGEGPGHSASAA----GAQARSTATQEE 479 Query: 1594 QAVPPPPTPPPPEALGGGDKLACGACGKLFSNMLILKTHEEHVHRRFLPFE--------- 1644 + T PE G C CGK F + LK H VH P++ Sbjct: 480 NGLLVGGT--RPEGGRGATGKDCPFCGKSFRSAHHLKVH-LRVHTGERPYKCPHCDYAGT 536 Query: 1645 ---ALSRYAAQFRKSYDSLYPPLAEPPKPPDGSLDSPVPHLG-PPFLVPEPEAGGTRAPE 1700 +L + + + S P PP+PP S P G P P G +P Sbjct: 537 QSGSLKYHLQRHHREQRSGAGP-GPPPEPPPPSQRGSAPQSGAKPSPQPATWVEGASSPR 595 Query: 1701 ERSRAGG 1707 S G Sbjct: 596 PPSSGAG 602 Score = 52.4 bits (124), Expect = 6e-06 Identities = 111/510 (21%), Positives = 156/510 (30%), Gaps = 122/510 (23%) Query: 1788 ACEGGSMPTGGGTGGASGCRRCHATFSCVFELVRHLK------KCYDDQTLEEEEEEAER 1841 A EG + P + A C C F E RHL KC +EEE Sbjct: 148 ATEGLARPQAPSSS-AFRCPYCKGKFRTSAERERHLHILHRPWKCGLCSFGSSQEEELLH 206 Query: 1842 GEEEEEVEEEEVEEEQGLEPPAGPEGPLPEPPDGEELSQAEATKAGGKEPEEKATPSPSP 1901 E PP P+ P P+ + Q E EPE +ATP+P+P Sbjct: 207 HSLTAHGAPERPLAATSAAPPPQPQPQPPPQPEPRSVPQPEPEP----EPEREATPTPAP 262 Query: 1902 A--------------------------------------HTCDQCAISFSSQDLLTSHRR 1923 A H C C F L +H + Sbjct: 263 AAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMK 322 Query: 1924 LHFL---------PSLQPSAPPQLLDLPLLVFGERNP-LVAATSPMPGPPLKRKHEDGSL 1973 +H P+ P+ PQ DL LL + P L+ A +P P + G L Sbjct: 323 VHASKLGPLRAPGPASGPARAPQPPDLGLLAYEPLGPALLLAPAPTPAERREPPSLLGYL 382 Query: 1974 SPTGSEAGGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKR 2033 S E GEG P R P + + R + EE + + Sbjct: 383 SLRAGEGRPNGEGAEPGPGRSFGGFRPLSSAL-------PARARRHRAEEPEEEEEVVEA 435 Query: 2034 VVQVWFQNTRARERKGQFRSTPGGVP--SPAVKPPATATPASLPKFNLLLGKVDDGTGRE 2091 + W + R+ PG P S + + A+ + LL+G GR Sbjct: 436 EEETWARG-RSLGSLASLHPRPGEGPGHSASAAGAQARSTATQEENGLLVGGTRPEGGRG 494 Query: 2092 APKREAP--AFPYPTA-------TLASGPQPFLPP----------------------GKE 2120 A ++ P + +A + +G +P+ P + Sbjct: 495 ATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRS 554 Query: 2121 ATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPES----EACSLSAGDLSDSSASSLAEPE 2176 P P P PPPP P+ K SP+ E S S + S +P Sbjct: 555 GAGPGPPPE----PPPPSQRGSAPQSGAKPSPQPATWVEGASSPRPPSSGAGPGSRRKPA 610 Query: 2177 SP------GAGGTS--------GGPGGGTG 2192 SP G GG + GPGG G Sbjct: 611 SPGRTLRNGRGGEAEPLDLSLRAGPGGEAG 640 Score = 46.6 bits (109), Expect = 3e-04 Identities = 99/420 (23%), Positives = 145/420 (34%), Gaps = 80/420 (19%) Query: 398 EGGTLPAPVGSPEDPSDPPQPYRL-ADDYTPAPAAFQGLSLSSHMSLLHSRNSCKTLKCP 456 EG AP G PS P L Y+ PA G +S SR + CP Sbjct: 2 EGSRPRAPSGHLA-PSPPAFDGELDLQRYSNGPAVSAGSLGMGAVSWSESRAGERRFPCP 60 Query: 457 KCNWHYKYQQTLDVHMREKHPESNS-HCSYCSAGGAHPRLARGESYNCGYKPYRCDVCNY 515 C +++ L +H+R HP + + C +C A L R S+ ++P R Sbjct: 61 VCGKRFRFNSILALHLR-AHPGAQAFQCPHCGHRAAQRALLR--SHLRTHQPER----PR 113 Query: 516 STTTKGNLSIHMQSDKHLANLQGFQAGPGGQGSPPEASLPPSAGDKEPKTKSSWQCKVC- 574 S + L + ++ A L ++ G Q +P L + + S+++C C Sbjct: 114 SPAARLLLELEERALLREARLGRARSSGGMQATPATEGL----ARPQAPSSSAFRCPYCK 169 Query: 575 -SYETNISRNLRIHMTSEKHMQNVLMLHQGLPLGLPPGLMGPGPPPPPGATPTSPPELFQ 633 + T+ R +H +LH+ GL + +S E Sbjct: 170 GKFRTSAERERHLH-----------ILHRPWKCGL-------------CSFGSSQEEELL 205 Query: 634 YFGPQALGQPQTPLAGPGLRPDKPLEAQLLLNGFHHVGAPARKFPTSAPGSLSPDAHLPP 693 + A G P+ PLA P + Q P + P S P P+ P Sbjct: 206 HHSLTAHGAPERPLAATSAAPPPQPQPQ----------PPPQPEPRSVP---QPEPEPEP 252 Query: 694 SQLLGSSSDSLPTSPP--PDDSLSLKVFRCLVCQAFSTDSLELLLYHCSIGRSLPEAEWK 751 + ++ PT P P++ + FRC VC T S L H K Sbjct: 253 ER------EATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSW-FLKGHMR----------K 295 Query: 752 EVAGDTHRCKLCCYGTQLKANFQLHLKTDKHAQKYQLAAHLREGGGAMG---TPSPASLG 808 A H C +C G K + L HA K LR G A G P P LG Sbjct: 296 HKASFDHACPVC--GRCFKEPWFLKNHMKVHASK---LGPLRAPGPASGPARAPQPPDLG 350 Score = 42.0 bits (97), Expect = 0.008 Identities = 31/118 (26%), Positives = 44/118 (37%), Gaps = 33/118 (27%) Query: 455 CPKCNWHYKYQQTLDVHMREKHPESNSHCSYCSAGGAHPRLARGESYNCGYKPYRCDVCN 514 CP C ++ L VH+R + G +PY+C C+ Sbjct: 500 CPFCGKSFRSAHHLKVHLR---------------------------VHTGERPYKCPHCD 532 Query: 515 YSTTTKGNLSIHMQSDKHLANLQGFQAGPGGQGSPPEAS---LPPSAGDKEPKTKSSW 569 Y+ T G+L H+Q H G AGPG PP S P +G K ++W Sbjct: 533 YAGTQSGSLKYHLQR-HHREQRSG--AGPGPPPEPPPPSQRGSAPQSGAKPSPQPATW 587 Score = 38.9 bits (89), Expect = 0.070 Identities = 46/206 (22%), Positives = 71/206 (34%), Gaps = 26/206 (12%) Query: 438 SSHMSLLHSR--NSCKTLKCPKCNWHYKYQQTLDVHMREKHPESNSHCSYCSAGGAHPRL 495 S+H +H R + KCP C++ +L H++ H E S P Sbjct: 509 SAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSGAGPGPPPEPPPPS 568 Query: 496 ARGESYNCGYKPYRCDVCNYSTTTKGNLSIHMQSD--------KHLANLQGFQAGPGGQG 547 RG + G KP +T +G S S K + + + G GG+ Sbjct: 569 QRGSAPQSGAKPSP----QPATWVEGASSPRPPSSGAGPGSRRKPASPGRTLRNGRGGEA 624 Query: 548 SPPEASLPPSAGDKEPKTKSSWQCKVCSYETNISRNLRIHMTSEKHMQNVLMLHQGLPLG 607 P + SL G + + +C C + T + +H+ + H G Sbjct: 625 EPLDLSLRAGPGGEAGPGGALHRCLFCPFATGAPELMALHLQ---------VHHSRRARG 675 Query: 608 LPPGLMGPGPP---PPPGATPTSPPE 630 P PP P G TP SP + Sbjct: 676 RRPPQADASPPYARVPSGETPPSPSQ 701 Score = 37.7 bits (86), Expect = 0.15 Identities = 51/219 (23%), Positives = 79/219 (36%), Gaps = 55/219 (25%) Query: 473 REKHPESNS-HCSYCSAGGAHPRLARGESYNCGYKPYRCDVCNYSTTTKGNLSIHMQSDK 531 R + P S++ C YC G R + ++P++C +C++ ++ + L +H Sbjct: 154 RPQAPSSSAFRCPYCK-GKFRTSAERERHLHILHRPWKCGLCSFGSSQEEEL-LHHSLTA 211 Query: 532 HLAN---LQGFQAGPGGQGSP-------------------PEASLPPS---AGDKEPKTK 566 H A L A P Q P PE P+ A +EP Sbjct: 212 HGAPERPLAATSAAPPPQPQPQPPPQPEPRSVPQPEPEPEPEREATPTPAPAAPEEPPAP 271 Query: 567 SSWQCKVCSYETNISRNLRIHMTSEK------------------HMQNVLMLHQGLPLGL 608 ++C+VC S L+ HM K ++N + +H LG Sbjct: 272 PEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHAS-KLG- 329 Query: 609 PPGLMGPGPPPPPGATPTSPPEL----FQYFGPQALGQP 643 L PGP P P PP+L ++ GP L P Sbjct: 330 --PLRAPGPASGPARAP-QPPDLGLLAYEPLGPALLLAP 365 Score = 34.7 bits (78), Expect = 1.3 Identities = 44/161 (27%), Positives = 55/161 (34%), Gaps = 12/161 (7%) Query: 2405 AGPGRPLPQRPMPDQTNTSTAGTTDPVPGPPTEPLGDKVSSERKPV--AGPTSSSNDALK 2462 AGPG P P+ P P Q ++ P P P T G SS R P AGP S A Sbjct: 556 AGPGPP-PEPPPPSQRGSAPQSGAKPSPQPATWVEG--ASSPRPPSSGAGPGSRRKPASP 612 Query: 2463 NLKALKTTVPALLGGQFLPFPLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNPMI 2522 T+ GG+ P L G A G L F L ++ + Sbjct: 613 G-----RTLRNGRGGEAEPLDLSLRAGPGGEAGPGGALHRCLFCPFATGAPELMALHLQV 667 Query: 2523 --PQTLIGLLPNALLQPPPQPPEPTATAPPKPPELPAPGEG 2561 + G P PP P+ PP P + G G Sbjct: 668 HHSRRARGRRPPQADASPPYARVPSGETPPSPSQEGEEGSG 708 Score = 32.7 bits (73), Expect = 5.0 Identities = 45/188 (23%), Positives = 65/188 (34%), Gaps = 38/188 (20%) Query: 569 WQCKVCSYETNISRNLRIHMTSEKHMQNVLMLHQGLPLGLPPGLMGPGPPPPPGATPTSP 628 ++C C Y S +L+ H+ Q G GP PPP P S Sbjct: 526 YKCPHCDYAGTQSGSLKYHLQRHHREQR----------------SGAGPGPPPEPPPPSQ 569 Query: 629 PELFQYFGPQALGQPQTPLAGPGLRPDKPLEAQLLLNGFHHVGAPARKFPTSAPGSLSPD 688 G + QP T + G P P G +R+ P S PG + Sbjct: 570 RGSAPQSGAKPSPQPATWVEGAS-SPRPPSSG---------AGPGSRRKPAS-PGRTLRN 618 Query: 689 AHLPPSQLLGSSSDSLPTSPPPDDSLSLKVFRCLVCQAFSTDSLELLLYHCSI------- 741 ++ L SL P + + RCL C F+T + EL+ H + Sbjct: 619 GRGGEAEPLDL---SLRAGPGGEAGPGGALHRCLFC-PFATGAPELMALHLQVHHSRRAR 674 Query: 742 GRSLPEAE 749 GR P+A+ Sbjct: 675 GRRPPQAD 682 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 64.7 bits (156), Expect = 1e-09 Identities = 85/278 (30%), Positives = 104/278 (37%), Gaps = 60/278 (21%) Query: 2327 PAPEAPPALK---APPATTPA-------------------SMPLGAAPTLPRLAPVLLSG 2364 P+P APP+L+ +PPAT P+ S PL T P AP L+ Sbjct: 304 PSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALAL 363 Query: 2365 PAL-------AQPPLGNLA-PFNSGPAASSGLLGLATSVLPTTTVVQT--AGPGRP--LP 2412 P L A PPL LA P P A + L A P + VQ + P P P Sbjct: 364 PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSP 423 Query: 2413 QRPMPDQTNTSTAGTTDPVPGPPTEPLGDKVS-SERKPVAGPTSSSNDALKNLKALKTTV 2471 P Q S A P+ PP+ P +S S P P + L+ K Sbjct: 424 SATPPSQAPPSLA--APPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAP 481 Query: 2472 PALLGGQFLPFPLPPAG--GTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNPMI--PQTLI 2527 PAL P PPA G AP F P PM+P+ P Sbjct: 482 PALATPPLQALPSPPASFPGQAP---FSPSAS--------------LPMSPLATPPPQAP 524 Query: 2528 GLLPNALLQPPPQPP-EPTATAPPKPPELPAPGEGEAG 2564 +L LLQ PP PP PT AP +PP P P +G Sbjct: 525 PVLAAPLLQVPPSPPASPTLQAPRRPP-TPGPDTSVSG 561 Score = 55.1 bits (131), Expect = 9e-07 Identities = 104/409 (25%), Positives = 142/409 (34%), Gaps = 75/409 (18%) Query: 2327 PAPEAPPALKAPPA----TTPASMPLGAAPTLPRLAPVLLSGP-------------ALAQ 2369 P +APP+L APP + PAS P+ + T P AP L+ P ALA Sbjct: 427 PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALAT 486 Query: 2370 PPLGNL----------APFNSGPAASSGLLGLATSVLPTTTVVQTAGPGRPLPQRPMPDQ 2419 PPL L APF+ P+AS + LAT P A P +P P P Sbjct: 487 PPLQALPSPPASFPGQAPFS--PSASLPMSPLATP--PPQAPPVLAAPLLQVP--PSPPA 540 Query: 2420 TNTSTAGTTDPVPGPPTEPLGDKVSSERKPVAGPTSSSNDALKNLKALKTTVPALLGGQF 2479 + T A P PGP T G +++ P P S + + + L G Sbjct: 541 SPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPS------------STLSG-- 586 Query: 2480 LPFPLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNPMIPQTLIGLLPNALLQPPP 2539 P G + A P+ Y G + G P P + A P Sbjct: 587 -----PDLAGHSSSATSTPEELRGYDS---GPEGGAAASPP--PDAELAACHPAAWSRGP 636 Query: 2540 QPPEPTATAPPKP-PELPAPGEGEAGEVDELLTGSTGISTVDVTH-RYLCRQCKMAFD-G 2596 PP AP P P PA G G A G+ T+ T A D G Sbjct: 637 APPLAFRGAPGAPLPWPPATGPGSA----------DGLCTIYETEGPESATPAPGALDPG 686 Query: 2597 EAPATAHQRSFCFFGRGSGGSMPPPLR---VPICTYHCLACEVLLSGREALASHLRSSAH 2653 +P T+ ++ G G+ P R +P+ + LLS LA+ A Sbjct: 687 PSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAA--AEGAA 744 Query: 2654 RRKAAPPQGGPPISITNAATAASAAVAFAKEEARLPHTDSNPKTTTTST 2702 P G +T A AA + + L D + + T+ T Sbjct: 745 GGSGGGPGGAEGGGVTGGARAALSDAELGRWAELLSPLDESRASITSVT 793 Score = 46.6 bits (109), Expect = 3e-04 Identities = 50/180 (27%), Positives = 63/180 (35%), Gaps = 62/180 (34%) Query: 2054 TPGGVPSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAP---------AFPYPT 2104 +P P P PP A P L K P +AP A P P Sbjct: 453 SPSATPPPQAPPPLAAPPLQLAK----------------PPPQAPPALATPPLQALPSPP 496 Query: 2105 ATLASGPQPFLP----PGKEATTPTPEPP----LPLL--PPPPPSEE--EGPEEPPKASP 2152 A+ G PF P P TP P+ P PLL PP PP+ + P PP P Sbjct: 497 ASF-PGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGP 555 Query: 2153 E----------------------SEACSLSAGDLSDSSASSLAEPESPGAGGTSGGPGGG 2190 + S + +LS DL+ S+S+ + PE G GP GG Sbjct: 556 DTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEE--LRGYDSGPEGG 613 Score = 46.2 bits (108), Expect = 4e-04 Identities = 82/333 (24%), Positives = 111/333 (33%), Gaps = 92/333 (27%) Query: 2329 PEAPPALKAPPATTPASMP-LGAAPTL---------------------PRLAPVLLSGPA 2366 P P + + PP TPA++ LGAA + PR P S P Sbjct: 27 PRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRPP 86 Query: 2367 LA-----QPPLGNLAPFNSGPAASSGLLGLATSVLPT----------TTVVQ---TAGPG 2408 + PP N +P GP +S G T P TV + T P Sbjct: 87 ASGRGERAPPAKNTSP---GPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPK 143 Query: 2409 R-------------PLPQRPMPDQTNTSTAGTTD---PVPGPPTEPLGDKVSSERKPVAG 2452 R P P P P S A T+ P P P P R P G Sbjct: 144 RSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARP--------RPPTEG 195 Query: 2453 PTSSSNDALKNLKALKTTV----PALLGGQFLPFPLPPAGGTAP---PAVFGPQLQGAYF 2505 P S + A ++ + P+ GG P + P PA GP +G Sbjct: 196 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPR 255 Query: 2506 QQLYGMK---KGLFPMNPMIPQTL---------IGLLPNALLQPPPQPPEPTATAPPKPP 2553 + + KGL + P PQ +G L ++ L P P+ +APP Sbjct: 256 APAHPSQPKPKGLQALRP--PQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQ 313 Query: 2554 ELPAPGEGEAGEVDELLTGSTGISTVDVTHRYL 2586 LP+P + T S G T+ TH +L Sbjct: 314 TLPSPPATPPSQA----TTSLGSPTLQATHSFL 342 Score = 43.9 bits (102), Expect = 0.002 Identities = 46/153 (30%), Positives = 60/153 (39%), Gaps = 31/153 (20%) Query: 1455 PFLSPPPPPLDLHRFPAPLFTPPVLPPFPLVPESLLKLQQQQLLLPFYLHDLKVGPKLTL 1514 PF PP PP+ AP F+PP PP + P + Q L L+V P Sbjct: 400 PFSPPPSPPVQ-----AP-FSPPASPP--VSPSATPPSQAPPSLAA---PPLQVPP---- 444 Query: 1515 AGPAPVLSLPAATPPPPPQPPKA----ELAEREWERPPMAKEGNEAGPSSPPDPLPNEAA 1570 + PA P+ATPPP PP A +LA+ + PP SPP P +A Sbjct: 445 SPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAP 504 Query: 1571 RTAAKALLENFGFELVIQYNEGKQAVPPPPTPP 1603 + + +L A PPP PP Sbjct: 505 FSPSASL------------PMSPLATPPPQAPP 525 Score = 43.1 bits (100), Expect = 0.004 Identities = 68/267 (25%), Positives = 88/267 (32%), Gaps = 71/267 (26%) Query: 2327 PAPEAPPAL-----KAP-----------PATTPASMPLGAAPTLPRLAPVLLSGPALAQP 2370 P+P+AP AL +AP P + PAS P+ + T P AP L+ P L P Sbjct: 384 PSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP 443 Query: 2371 PLGNLAPFNSGPAASSGLLGLATSVLPTTTVVQTAGP----GRPLPQRPMPDQTNTSTAG 2426 P P AS + AT P A P +P PQ P T A Sbjct: 444 P---------SPPASPPMSPSATP--PPQAPPPLAAPPLQLAKPPPQAPPALATPPLQAL 492 Query: 2427 TTDPVPGPPTEPLGDKVSSERKPVAGPTSSSNDALKNLKALKTTVPALLGGQFLPFPLPP 2486 + P P P S P+A P + P +L L P Sbjct: 493 PSPPASFPGQAPFSPSASLPMSPLATPPPQA--------------PPVLAAPLLQVP--- 535 Query: 2487 AGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNPMI--PQTLIG--LLPNALLQPPPQPP 2542 +PPA P LQ P P P T + L AL PP PP Sbjct: 536 ---PSPPA--SPTLQA--------------PRRPPTPGPDTSVSGPRLTLALAPGPPPPP 576 Query: 2543 EPTATAPPKPPELPAPGEGEAGEVDEL 2569 + ++ P+L +EL Sbjct: 577 SRSPSSTLSGPDLAGHSSSATSTPEEL 603 Score = 42.7 bits (99), Expect = 0.005 Identities = 38/116 (32%), Positives = 46/116 (39%), Gaps = 16/116 (13%) Query: 605 PLGLPPGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRPDKPLEAQLLL 664 PL PP P PP P SPP P +PLA P + L LL Sbjct: 349 PLATPPPQAPPALALPPLQAPPSPPA----------SPPLSPLATPSPQAPNALAVHLLQ 398 Query: 665 NGFHHVGAPARKFPTSAPGS--LSPDAHLPPSQL---LGSSSDSLPTSPPPDDSLS 715 F +P + P S P S +SP A PPSQ L + +P SPP +S Sbjct: 399 APFSPPPSPPVQAPFSPPASPPVSPSA-TPPSQAPPSLAAPPLQVPPSPPASPPMS 453 Score = 41.6 bits (96), Expect = 0.011 Identities = 36/135 (26%), Positives = 50/135 (37%), Gaps = 13/135 (9%) Query: 2058 VPSPAVKPPATATPA----SLPKFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQP 2113 +PSP PP+ AT + +L + L P + PA P P P Sbjct: 315 LPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-P 373 Query: 2114 FLPPGKEATTPTPEPPLPL--------LPPPPPSEEEGPEEPPKASPESEACSLSAGDLS 2165 PP TP+P+ P L PPP + P PP + P S + + + Sbjct: 374 ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 433 Query: 2166 DSSASSLAEPESPGA 2180 +A L P SP A Sbjct: 434 SLAAPPLQVPPSPPA 448 Score = 40.4 bits (93), Expect = 0.024 Identities = 39/123 (31%), Positives = 45/123 (36%), Gaps = 19/123 (15%) Query: 605 PLGLPPGLMGPG---PPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRPDKPLEAQ 661 P PP L P PP PP + P SP P L P LA P P P Sbjct: 428 PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKP--PPQAP--PA 483 Query: 662 LLLNGFHHVGAPARKFPTSAPGSLSPDAHLPPSQL----------LGSSSDSLPTSPPPD 711 L + +P FP AP SP A LP S L L + +P SPP Sbjct: 484 LATPPLQALPSPPASFPGQAP--FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPAS 541 Query: 712 DSL 714 +L Sbjct: 542 PTL 544 Score = 40.0 bits (92), Expect = 0.031 Identities = 109/465 (23%), Positives = 149/465 (32%), Gaps = 96/465 (20%) Query: 1218 LSPLEGPNLTP---EASP--DPLPEPPLASVEVPDKPSGSPGQPPS--PAPSPVPEPDAQ 1270 L L P +TP +A+P PL PLA+ PS P PPS PSP P +Q Sbjct: 268 LQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPS--PSAPPSLQTLPSPPATPPSQ 325 Query: 1271 AEDVAPPPTMAEEEEGTTGELRSAEPAPADSRHPLTYRKTTNFALDKFL----DPARPYK 1326 A PT+ + T L S +P + P + AL PA P Sbjct: 326 ATTSLGSPTL----QATHSFLPSPPLSPLATPPP---QAPPALALPPLQAPPSPPASPPL 378 Query: 1327 CTVCKESFTQKNILLVHYNSVSHLHKMKKAAIDPSAPARGEAGAPPTTTAATDKPFKCTV 1386 + S N L VH P +P +P T + P Sbjct: 379 SPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP----- 433 Query: 1387 CRVSYNQSSTLEIHMRSVLHQTRSRGTKTDSKIEGPERSQEEPKEGETEGEVGTEKKGPD 1446 +L V + + S P Q P ++ K P Sbjct: 434 ---------SLAAPPLQVPPSPPASPPMSPSATPPP---QAPPPLAAPPLQLA--KPPPQ 479 Query: 1447 TSGFISGLPFLSPPPPPLDLHRFP-------------APLFTPPVLPPFPLVPESLLKLQ 1493 ++ P + P PP FP +PL TPP P P++ LL++ Sbjct: 480 APPALATPPLQALPSPPAS---FPGQAPFSPSASLPMSPLATPPPQAP-PVLAAPLLQVP 535 Query: 1494 QQQLLLPFYLHDLKV---GPKLTLAGPAPVLSLPAATPPPPPQPPKAELA-------ERE 1543 P + GP +++GP L+L PPPP + P + L+ Sbjct: 536 PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSS 595 Query: 1544 WERPPMAKEGNEAGP------SSPPD--------------PLPNEAARTAAKALLE---- 1579 P G ++GP S PPD P P A R A A L Sbjct: 596 ATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPA 655 Query: 1580 ----NFGFELVIQYNEGKQAVPPPP--TPPPPEALGGGDKLACGA 1618 + I EG ++ P P P P G K A GA Sbjct: 656 TGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGA 700 Score = 40.0 bits (92), Expect = 0.031 Identities = 36/129 (27%), Positives = 46/129 (35%), Gaps = 11/129 (8%) Query: 2049 GQFRSTPGGVPSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAFPYPTATLA 2108 G S+P PSP+ PP+ + P SL P + + PT Sbjct: 288 GPLSSSPLATPSPSA-PPSPSAPPSLQTL--------PSPPATPPSQATTSLGSPTLQAT 338 Query: 2109 SGPQPFLPPGKEATTPTPEPPLPLLPP--PPPSEEEGPEEPPKASPESEACSLSAGDLSD 2166 P P AT P PP LPP PPS P P A+P +A + A L Sbjct: 339 HSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ 398 Query: 2167 SSASSLAEP 2175 + S P Sbjct: 399 APFSPPPSP 407 Score = 39.3 bits (90), Expect = 0.053 Identities = 30/99 (30%), Positives = 41/99 (41%), Gaps = 13/99 (13%) Query: 2059 PSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQPFLPPG 2118 PSP V+ P + PAS P P + P+ P + P P PP Sbjct: 405 PSPPVQAPFSP-PASPPV----------SPSATPPSQAPPSLAAPPLQVPPSP-PASPPM 452 Query: 2119 KEATTPTPEPPLPLLPPPPPSEEEGPEEPPK-ASPESEA 2156 + TP P+ P PL PP + P+ PP A+P +A Sbjct: 453 SPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQA 491 Score = 38.9 bits (89), Expect = 0.070 Identities = 75/292 (25%), Positives = 92/292 (31%), Gaps = 72/292 (24%) Query: 1453 GLPFLSPP---PPPLDLHRF-----PAPLFTP-PVLPPFPLVPESLLKLQQQQLLLPFYL 1503 GL L PP PP D +PL TP P PP P P SL L P Sbjct: 267 GLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQA 326 Query: 1504 HDLKVGPKLTLAG---PAPVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPSS 1560 P L P+P LS P ATPPP P LA + PP P + Sbjct: 327 TTSLGSPTLQATHSFLPSPPLS-PLATPPPQAPPA---LALPPLQAPPSPPASPPLSPLA 382 Query: 1561 PPDPLPNEAARTAAKALLENFGFELVIQYNEGKQAVPPPPTPP--PPEALGGGDKLACGA 1618 P P +A A LL+ PPP+PP P + ++ A Sbjct: 383 TPSP---QAPNALAVHLLQ--------------APFSPPPSPPVQAPFSPPASPPVSPSA 425 Query: 1619 CGKLFSNMLILKTHEEHVHRRFLPFEALSRYAAQFRKSYDSLYPPLAEPPKPPDGSLDSP 1678 P +A AA PPL PP PP SP Sbjct: 426 TP---------------------PSQAPPSLAA----------PPLQVPPSPPASPPMSP 454 Query: 1679 V----PHLGPPFLVPEPEAGGTRAPEERSRAGGHWPIEEEESSRGNLPPLVP 1726 P PP P + + P + A P++ S + P P Sbjct: 455 SATPPPQAPPPLAAPPLQL--AKPPPQAPPALATPPLQALPSPPASFPGQAP 504 Score = 38.1 bits (87), Expect = 0.12 Identities = 40/133 (30%), Positives = 48/133 (36%), Gaps = 28/133 (21%) Query: 2061 PAVKPPAT-ATPASLPKFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQPFLPPGK 2119 P V PP A PA P + L P AP P +L + P P P Sbjct: 274 PQVTPPRKDAAPALGPLSSSPLA---------TPSPSAPPSPSAPPSLQTLPSPPATPPS 324 Query: 2120 EATT----PT--------PEPPLPLLPPPPPSEEEGPEEPPKASPESEACSLSAGDLSDS 2167 +ATT PT P PPL L PPP PP +P S S L+ Sbjct: 325 QATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATP 384 Query: 2168 SASSLAEPESPGA 2180 S P++P A Sbjct: 385 S------PQAPNA 391 Score = 36.2 bits (82), Expect = 0.45 Identities = 29/95 (30%), Positives = 39/95 (41%), Gaps = 18/95 (18%) Query: 1213 SLYFLLSPLEGPNLTPEASP-DPLPEPPLASVEVPDKPSGSPGQ--------PPSPAPSP 1263 +++ L +P P P +P P PP++ P PS +P PPSP SP Sbjct: 393 AVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATP--PSQAPPSLAAPPLQVPPSPPASP 450 Query: 1264 VPEPDAQAEDVAPPPTMAEEEEGTTGELRSAEPAP 1298 P A APPP A L+ A+P P Sbjct: 451 PMSPSATPPPQAPPPLAAP-------PLQLAKPPP 478 Score = 35.4 bits (80), Expect = 0.77 Identities = 81/365 (22%), Positives = 113/365 (30%), Gaps = 63/365 (17%) Query: 72 EIGEPQEGPDCGHFPPNDPGVEKDKEQEEEEEGLPPMDLSNHLFFTAGGEAYLVAKLSLP 131 E+G P+ P PP + G K E P + GG ++ Sbjct: 177 EVGLPRPAPSARPRPPTE-GPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS 235 Query: 132 GGSELLLPKGFPWGEAGIKEEPSLPFLAYPPPSHLTALHIQHGFDPIQGFSSS-DQILSH 190 + L P G P+ P + P P L AL P + + + + S Sbjct: 236 SATPLSSPARSGPSARGTPRAPAHP--SQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS 293 Query: 191 DTSAPSPAACEERHGAFWSYQLAPNPPGDPKDGPMGNSGGNHVAVFWLCLLCRLGFSKPQ 250 + PSP+A A S Q P+PP P + G P Sbjct: 294 PLATPSPSA-PPSPSAPPSLQTLPSPPATPPSQATTSLGS------------------PT 334 Query: 251 AFMDHTQSHGVKLTPAQYQGLSGSPAVLQEGDEGCKALISFLEP-KLPARPSSDIPLDNS 309 H+ L+P PA+ L P + P P + PL Sbjct: 335 LQATHSFLPSPPLSPLATPPPQAPPALA-------------LPPLQAPPSPPASPPLSPL 381 Query: 310 STVNMEANVAQTEDGPPEAEVQALILLDEEVMALSPPSPPTATWDPSPTQAKESPVAAGE 369 +T + +A P A L+ + PPSPP QA SP A+ Sbjct: 382 ATPSPQA---------PNALAVHLL----QAPFSPPPSPPV--------QAPFSPPASPP 420 Query: 370 AGPDWFPEGQEEDGGLCPPLNQSSPTSKEGGTLPAPVGSPEDPSDPP---QPYRLADDYT 426 P P Q PPL P S +P +P + PP P +LA Sbjct: 421 VSPSATPPSQAPPSLAAPPL--QVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPP 478 Query: 427 PAPAA 431 AP A Sbjct: 479 QAPPA 483 Score = 33.5 bits (75), Expect = 2.9 Identities = 52/185 (28%), Positives = 67/185 (36%), Gaps = 47/185 (25%) Query: 1518 APVLSLPAA-----TPPPPPQP-PKAELAEREWERPPMAKEGNEA-GP-SSPPDPLPNEA 1569 +P S P+A P P QP PK A R + P K+ A GP SS P P+ + Sbjct: 242 SPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPS 301 Query: 1570 ARTAAKALLENFGFELVIQYNEGKQAVPPPPTPPPPEALGGGDKLACGACGKLFSNMLIL 1629 A + A Q +P PP PP +A + + Sbjct: 302 APPSPSA-------------PPSLQTLPSPPATPPSQATTS------------LGSPTLQ 336 Query: 1630 KTHEEHVHRRFLPFEALSRYAAQFRKSYDSL-YPPLAEPPKPPDGSLDSPVPHLGPPFLV 1688 TH FLP LS A ++ +L PPL PP PP P L P Sbjct: 337 ATHS------FLPSPPLSPLATPPPQAPPALALPPLQAPPSPPAS------PPLS-PLAT 383 Query: 1689 PEPEA 1693 P P+A Sbjct: 384 PSPQA 388 Score = 33.1 bits (74), Expect = 3.8 Identities = 47/161 (29%), Positives = 55/161 (34%), Gaps = 29/161 (18%) Query: 2053 STPGGVPSPAVKPPATATPASLPKFNLLLGK---VDDGTGREAPKREAPAFPYPTATLAS 2109 ++PG V SP + T P L + L + V G EAPKR A + T S Sbjct: 100 TSPGPVSSPG-RASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDT--S 156 Query: 2110 GPQPFLPP----------GKEATTPTPEPPLPLLPPPP--------PSEEEGPEEPPKAS 2151 GP P P G E P P P PP SE E P A Sbjct: 157 GPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAAR 216 Query: 2152 PESEA---CSLSAGDLSDSSASSLAEP--ESPGAGGTSGGP 2187 A A SSA+ L+ P P A GT P Sbjct: 217 RRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAP 257 Score = 32.7 bits (73), Expect = 5.0 Identities = 48/183 (26%), Positives = 57/183 (31%), Gaps = 42/183 (22%) Query: 548 SPPEASLPPSAGDKEPKTKSSWQCKVCSYETNISRNLRIHMTSEKHMQNVLMLHQ-GLPL 606 +PP +LPP P S L T N L +H P Sbjct: 357 APPALALPPLQAPPSPPA---------------SPPLSPLATPSPQAPNALAVHLLQAPF 401 Query: 607 GLPPGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQ-----TPLAGPGLRPD------ 655 PP P PP + P SP P +L P +P A P + P Sbjct: 402 SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 461 Query: 656 --KPLEAQLLLNGFHHVGAPARKFPTSAPGSLSPDAHLPPSQLLGSSSDSLPTSPPPDDS 713 PL A L K P AP +L+ PP Q L S S P P S Sbjct: 462 APPPLAAPPL---------QLAKPPPQAPPALA----TPPLQALPSPPASFPGQAPFSPS 508 Query: 714 LSL 716 SL Sbjct: 509 ASL 511 Score = 32.7 bits (73), Expect = 5.0 Identities = 28/101 (27%), Positives = 39/101 (38%), Gaps = 19/101 (18%) Query: 2059 PSPAVKPPAT--ATPASLPKFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQPFLP 2116 PSP PP + ATP+ L + + +AP P P+ + + PF P Sbjct: 370 PSPPASPPLSPLATPSPQAPNALAVHLL-----------QAPFSPPPSPPVQA---PFSP 415 Query: 2117 PGKEATTPTPEPPL---PLLPPPPPSEEEGPEEPPKASPES 2154 P +P+ PP P L PP P P SP + Sbjct: 416 PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSA 456 Score = 32.7 bits (73), Expect = 5.0 Identities = 51/195 (26%), Positives = 65/195 (33%), Gaps = 61/195 (31%) Query: 2060 SPAVKPPATATPASLPKFNLLLGKVDDGTGR--------EAPKREAPAFPYPTATLAS-- 2109 +P PP + +P+S L G T P+ A A P P A LA+ Sbjct: 569 APGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACH 628 Query: 2110 ------GPQPFLPPGKEATTPTPEPPLPLLPPPPPS---------EEEGPEEP------- 2147 GP P L A P PLP P P E EGPE Sbjct: 629 PAAWSRGPAPPL-----AFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGAL 683 Query: 2148 -PKASPESEACSLSAGDLSDSSASSLAEP---ESP--------------------GAGGT 2183 P SP + +AG + +S+ S + E P A G Sbjct: 684 DPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGA 743 Query: 2184 SGGPGGGTGVPDGMG 2198 +GG GGG G +G G Sbjct: 744 AGGSGGGPGGAEGGG 758 >gi|148277064 cut-like homeobox 1 isoform a [Homo sapiens] Length = 1505 Score = 64.3 bits (155), Expect = 2e-09 Identities = 65/242 (26%), Positives = 94/242 (38%), Gaps = 27/242 (11%) Query: 1964 LKRKHEDGSLSP------TGSEAGGGGEGEPPRD-KRLRTTILPEQLEILYRWYMQDSNP 2016 +KR+H S S G+E G +P K+ R + PE+ E L R Y Q P Sbjct: 1210 MKRRHSSVSDSQPCEPPSVGTEYSQGASPQPQHQLKKPRVVLAPEEKEALKRAYQQKPYP 1269 Query: 2017 TRKMLDCISEEVGLKKRVVQVWFQNTRARERKGQF-RSTPGGVPSPAVKPPATATPASLP 2075 + K ++ ++ ++ LK V WF N R+R R+ F G A A+ +P++ Sbjct: 1270 SPKTIEDLATQLNLKTSTVINWFHNYRSRIRRELFIEEIQAGSQGQA---GASDSPSA-- 1324 Query: 2076 KFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQPFLPPGKEATTPTPEPPLPL-LP 2134 +GR AP E + AT G P + E P P Sbjct: 1325 -----------RSGRAAPSSEGDSCDGVEATEGPGSADTEEPKSQGEAEREEVPRPAEQT 1373 Query: 2135 PPPPSEEEGPEEPPKASPESEACSLSAGDLSDSSASSLAEPESPGAGGTS--GGPGGGTG 2192 PPPS GP++ E S +SA++ A P +P TS PG G Sbjct: 1374 EPPPSGTPGPDDARDDDHEGGPVEGPGPLPSPASATATAAPAAPEDAATSAAAAPGEGPA 1433 Query: 2193 VP 2194 P Sbjct: 1434 AP 1435 Score = 50.4 bits (119), Expect = 2e-05 Identities = 54/200 (27%), Positives = 80/200 (40%), Gaps = 23/200 (11%) Query: 1740 QTQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARK----NACEGGSMP 1795 + +AL+ ++ YP +E LA+ L L + V+ WF N R + R+ + GS Sbjct: 1255 EKEALKRAYQQKPYPSPKTIEDLATQLNLKTSTVINWFHNYRSRIRRELFIEEIQAGSQG 1314 Query: 1796 TGGGTGGASGCRRCHATFSCVFELVRHLKKCYDDQTLEEEEEEAERGEEEEEVEEEEVEE 1855 G + S R A S + ++ + + EE +++ E EEV Sbjct: 1315 QAGASDSPS-ARSGRAAPSSEGDSCDGVEATEGPGSADTEEPKSQGEAEREEVPR---PA 1370 Query: 1856 EQGLEPPAGPEGPLPEPPDGEELSQAEATKAGGKEPEEKATPSPSPAHTCDQCAISFSSQ 1915 EQ PP+G GP D E GG P E P PSPA + A + + Sbjct: 1371 EQTEPPPSGTPGPDDARDDDHE---------GG--PVEGPGPLPSPA-SATATAAPAAPE 1418 Query: 1916 DLLTSHRRLHFLPSLQPSAP 1935 D TS P P+AP Sbjct: 1419 DAATSAAA---APGEGPAAP 1435 Score = 33.1 bits (74), Expect = 3.8 Identities = 26/94 (27%), Positives = 38/94 (40%), Gaps = 6/94 (6%) Query: 1220 PLEGPNLTPEASPDPLPEPPLASVEVPDKPSGSPGQPPSPAPSPVPEPDAQAEDVAP-PP 1278 P+EGP P + P A + + +PG+ P+ APS P P + AP P Sbjct: 1395 PVEGPGPLPSPASATATAAPAAPEDAATSAAAAPGEGPA-APSSAPPPSNSSSSSAPRRP 1453 Query: 1279 TMAEEEEGTTGELRSAEPAPADSRHPLTYRKTTN 1312 + + G L A A +PL +K N Sbjct: 1454 SSLQSLFG----LPEAAGARDSRDNPLRKKKAAN 1483 Score = 32.0 bits (71), Expect = 8.5 Identities = 26/80 (32%), Positives = 31/80 (38%), Gaps = 13/80 (16%) Query: 1527 TPPPPPQPPKAELAEREWERPPMAKEGNEAGPSSPPDPLPN--EAARTAAKALLENFGFE 1584 T PPP P + A + +E GP P PLP+ A TAA A E+ Sbjct: 1373 TEPPPSGTPGPDDAR---------DDDHEGGPVEGPGPLPSPASATATAAPAAPEDAATS 1423 Query: 1585 LVIQYNEGKQAVPPPPTPPP 1604 EG A P PPP Sbjct: 1424 AAAAPGEGPAA--PSSAPPP 1441 >gi|30023847 LIM homeobox protein 3 isoform a [Homo sapiens] Length = 397 Score = 64.3 bits (155), Expect = 2e-09 Identities = 66/227 (29%), Positives = 86/227 (37%), Gaps = 38/227 (16%) Query: 1992 KRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQNTRARERK--- 2048 KR RTTI +QLE L Y P R + + +S E GL RVVQVWFQN RA+E++ Sbjct: 158 KRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKK 217 Query: 2049 -------GQF-----RSTPGGV---------------------PSPAVKPPATATPASLP 2075 GQ+ RS G PS A PA SL Sbjct: 218 DAGRQRWGQYFRNMKRSRGGSKSDKDSVQEGQDSDAEVSFPDEPSLAEMGPANGLYGSLG 277 Query: 2076 KFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQPFLPPGKEA--TTPTPEPPLPLL 2133 + LG+ G + + A P L G +PP A + P P+P L L Sbjct: 278 EPTQALGRPSGALGNFSLEHGGLAGPEQYRELRPGSPYGVPPSPAAPQSLPGPQPLLSSL 337 Query: 2134 PPPPPSEEEGPEEPPKASPESEACSLSAGDLSDSSASSLAEPESPGA 2180 P S P P P + + S+ SS P+ P + Sbjct: 338 VYPDTSLGLVPSGAPGGPPPMRVLAGNGPSSDLSTGSSGGYPDFPAS 384 Score = 55.5 bits (132), Expect = 7e-07 Identities = 61/231 (26%), Positives = 88/231 (38%), Gaps = 47/231 (20%) Query: 2200 RRYRTQMSSLQLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAKL 2259 +R RT +++ QL+ +K+ Y P E L E GL RV+QVWFQN RAKEK+ K Sbjct: 158 KRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKK 217 Query: 2260 QG----------TAAGSTGGSSEGLLAAQRTDCPYCDVKYDFYVSCR---------GHL- 2299 S GGS + Q +V + S G L Sbjct: 218 DAGRQRWGQYFRNMKRSRGGSKSDKDSVQEGQDSDAEVSFPDEPSLAEMGPANGLYGSLG 277 Query: 2300 ---------------FSRQHLAKLKEAVRAQLKSESKCYDLAPAPEAPPALKAP------ 2338 FS +H +L+ S Y + P+P AP +L P Sbjct: 278 EPTQALGRPSGALGNFSLEHGGLAGPEQYRELRPGSP-YGVPPSPAAPQSLPGPQPLLSS 336 Query: 2339 ---PATTPASMPLGAAPTLPRLAPVLLSGPA--LAQPPLGNLAPFNSGPAA 2384 P T+ +P GA P + + +GP+ L+ G F + PA+ Sbjct: 337 LVYPDTSLGLVPSGAPGGPPPMRVLAGNGPSSDLSTGSSGGYPDFPASPAS 387 Score = 45.8 bits (107), Expect = 6e-04 Identities = 57/220 (25%), Positives = 81/220 (36%), Gaps = 36/220 (16%) Query: 1733 RTKFTEFQTQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARKNACEGG 1792 RT T Q + L+S + TS P E+L+S GL RVV VWFQN R K ++ + G Sbjct: 161 RTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAG 220 Query: 1793 SMPTGGGTGGASGCRRCHATFSCVFELVRHLKKCYDDQTLEEEE-EEAERGEEEEEVEEE 1851 G + R++K+ +++ +E + + E +E Sbjct: 221 RQRWG--------------------QYFRNMKRSRGGSKSDKDSVQEGQDSDAEVSFPDE 260 Query: 1852 EVEEEQGLEPPAGPEGPLPEP------PDGE--ELSQAEATKAGGKEPEEKATPS----- 1898 E G P G G L EP P G S AG ++ E S Sbjct: 261 PSLAEMG--PANGLYGSLGEPTQALGRPSGALGNFSLEHGGLAGPEQYRELRPGSPYGVP 318 Query: 1899 PSPAHTCDQCAISFSSQDLLTSHRRLHFLPSLQPSAPPQL 1938 PSPA L+ L +PS P PP + Sbjct: 319 PSPAAPQSLPGPQPLLSSLVYPDTSLGLVPSGAPGGPPPM 358 >gi|7657303 LIM homeobox protein 3 isoform b [Homo sapiens] Length = 402 Score = 64.3 bits (155), Expect = 2e-09 Identities = 66/227 (29%), Positives = 86/227 (37%), Gaps = 38/227 (16%) Query: 1992 KRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQNTRARERK--- 2048 KR RTTI +QLE L Y P R + + +S E GL RVVQVWFQN RA+E++ Sbjct: 163 KRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKK 222 Query: 2049 -------GQF-----RSTPGGV---------------------PSPAVKPPATATPASLP 2075 GQ+ RS G PS A PA SL Sbjct: 223 DAGRQRWGQYFRNMKRSRGGSKSDKDSVQEGQDSDAEVSFPDEPSLAEMGPANGLYGSLG 282 Query: 2076 KFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQPFLPPGKEA--TTPTPEPPLPLL 2133 + LG+ G + + A P L G +PP A + P P+P L L Sbjct: 283 EPTQALGRPSGALGNFSLEHGGLAGPEQYRELRPGSPYGVPPSPAAPQSLPGPQPLLSSL 342 Query: 2134 PPPPPSEEEGPEEPPKASPESEACSLSAGDLSDSSASSLAEPESPGA 2180 P S P P P + + S+ SS P+ P + Sbjct: 343 VYPDTSLGLVPSGAPGGPPPMRVLAGNGPSSDLSTGSSGGYPDFPAS 389 Score = 55.5 bits (132), Expect = 7e-07 Identities = 61/231 (26%), Positives = 88/231 (38%), Gaps = 47/231 (20%) Query: 2200 RRYRTQMSSLQLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAKL 2259 +R RT +++ QL+ +K+ Y P E L E GL RV+QVWFQN RAKEK+ K Sbjct: 163 KRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKK 222 Query: 2260 QG----------TAAGSTGGSSEGLLAAQRTDCPYCDVKYDFYVSCR---------GHL- 2299 S GGS + Q +V + S G L Sbjct: 223 DAGRQRWGQYFRNMKRSRGGSKSDKDSVQEGQDSDAEVSFPDEPSLAEMGPANGLYGSLG 282 Query: 2300 ---------------FSRQHLAKLKEAVRAQLKSESKCYDLAPAPEAPPALKAP------ 2338 FS +H +L+ S Y + P+P AP +L P Sbjct: 283 EPTQALGRPSGALGNFSLEHGGLAGPEQYRELRPGSP-YGVPPSPAAPQSLPGPQPLLSS 341 Query: 2339 ---PATTPASMPLGAAPTLPRLAPVLLSGPA--LAQPPLGNLAPFNSGPAA 2384 P T+ +P GA P + + +GP+ L+ G F + PA+ Sbjct: 342 LVYPDTSLGLVPSGAPGGPPPMRVLAGNGPSSDLSTGSSGGYPDFPASPAS 392 Score = 45.8 bits (107), Expect = 6e-04 Identities = 57/220 (25%), Positives = 81/220 (36%), Gaps = 36/220 (16%) Query: 1733 RTKFTEFQTQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARKNACEGG 1792 RT T Q + L+S + TS P E+L+S GL RVV VWFQN R K ++ + G Sbjct: 166 RTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAG 225 Query: 1793 SMPTGGGTGGASGCRRCHATFSCVFELVRHLKKCYDDQTLEEEE-EEAERGEEEEEVEEE 1851 G + R++K+ +++ +E + + E +E Sbjct: 226 RQRWG--------------------QYFRNMKRSRGGSKSDKDSVQEGQDSDAEVSFPDE 265 Query: 1852 EVEEEQGLEPPAGPEGPLPEP------PDGE--ELSQAEATKAGGKEPEEKATPS----- 1898 E G P G G L EP P G S AG ++ E S Sbjct: 266 PSLAEMG--PANGLYGSLGEPTQALGRPSGALGNFSLEHGGLAGPEQYRELRPGSPYGVP 323 Query: 1899 PSPAHTCDQCAISFSSQDLLTSHRRLHFLPSLQPSAPPQL 1938 PSPA L+ L +PS P PP + Sbjct: 324 PSPAAPQSLPGPQPLLSSLVYPDTSLGLVPSGAPGGPPPM 363 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 63.2 bits (152), Expect = 3e-09 Identities = 121/497 (24%), Positives = 172/497 (34%), Gaps = 73/497 (14%) Query: 2094 KREAPAFPYPTATLASGPQPFLPPGKEATTPTPEPPLPLLPPP-------------PPSE 2140 K +A A A A G PPG +P PP P+ P P +E Sbjct: 7 KAKAGAAARTPAARAPGLLTPRPPG------SPRPPPPVTPAALRVLGAAGAVGRKPLAE 60 Query: 2141 EEG-------PEEPPKASPESEACSLSAGDLSDSSASSLAEPESPGAGGTSGGP------ 2187 G PE P+A P A + S S AS E +P A TS GP Sbjct: 61 RAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGE-RAPPAKNTSPGPVSSPGR 119 Query: 2188 GGGTGVPDGMGQRRYRTQMSSLQLKIMKACYEAYRTPTMQ---ECEVLGEEIGLPKRVIQ 2244 GT P +GQ+ R +S+ + EA + + + G G P Sbjct: 120 ASGTTRPGPLGQKGLR--ISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTP----- 172 Query: 2245 VWFQNARAKEKKAKLQGTAAGSTGGSSEGLLAAQRTDCPYCDVKYDFYVSCRGHLFSRQH 2304 + A ++++ GT G + T+ P V S H + Sbjct: 173 -----SPAMARRSRAAGTEVG-LPRPAPSARPRPPTEGPRKSVS-----SASEHSTTEPS 221 Query: 2305 LA--KLKEAVRAQLKSESKCYDLAPAPEAPPALKAPPATTPASMPLGAAPTLPRLAPVLL 2362 A + A + S+ + P + PA P A P A P+ P+ + Sbjct: 222 PAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAP--AHPSQPKPKGLQA 279 Query: 2363 SGPALAQPPLGNLAPFNSGPAASSGLLGLATSVLPTTTVVQTAGPGRPLPQRPMPDQTNT 2422 P PP + AP GP +SS L + S +Q+ P P P +++ Sbjct: 280 LRPPQVTPPRKDAAP-ALGPLSSSPLATPSPS-----AALQSQAP----PTLPATPHSSS 329 Query: 2423 STAGTTDPVP-GPPTEPLGDKVSSERKPVAGPTSSSNDALKNLKALKTTVPALLGGQFLP 2481 T P+P PP+ + + P A P S + +L + L+ T L P Sbjct: 330 LTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGS-PTLQATHSFLPSPPLSP 388 Query: 2482 FPLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNPMIPQTLIGLLPNALLQPPPQP 2541 PP APPA+ P LQ L +P P L L A PPP P Sbjct: 389 LATPPP--QAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP 446 Query: 2542 PEPTATAPP-KPPELPA 2557 P +PP PP P+ Sbjct: 447 PVQAPFSPPASPPVSPS 463 Score = 62.4 bits (150), Expect = 6e-09 Identities = 77/252 (30%), Positives = 91/252 (36%), Gaps = 57/252 (22%) Query: 2327 PAPEAPPALKAPPATTPASMPLG--------AAPTLPR-LAPVLLSGPALAQPPLGNLAP 2377 P P+APPAL PP P S P +P P LA LL P P AP Sbjct: 392 PPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAP 451 Query: 2378 FNSGPAASSGLLGLATSVLPTTTVVQTAGPGRPLPQRPMPDQTNTSTAGTTDPVPGPPTE 2437 F+ P AS + AT P+ A P PL P P + + T P PP Sbjct: 452 FS--PPASPPVSPSATP--PSQAPPSLAAP--PLQVPPSPPASPPMSPSATPPPQAPP-- 503 Query: 2438 PLGDKVSSERKPVAGPTSSSNDALKNLKALKTTVPALLGGQFLPFPLPPAG--GTAPPAV 2495 P+A P L+ K PAL P PPA G AP Sbjct: 504 -----------PLAAP------PLQLAKPPPQAPPALATPPLQALPSPPASFPGQAP--- 543 Query: 2496 FGPQLQGAYFQQLYGMKKGLFPMNPMI--PQTLIGLLPNALLQPPPQPP-EPTATAPPKP 2552 F P PM+P+ P +L LLQ PP PP PT AP +P Sbjct: 544 FSPSAS--------------LPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRP 589 Query: 2553 PELPAPGEGEAG 2564 P P P +G Sbjct: 590 P-TPGPDTSVSG 600 Score = 55.1 bits (131), Expect = 9e-07 Identities = 104/409 (25%), Positives = 142/409 (34%), Gaps = 75/409 (18%) Query: 2327 PAPEAPPALKAPPA----TTPASMPLGAAPTLPRLAPVLLSGP-------------ALAQ 2369 P +APP+L APP + PAS P+ + T P AP L+ P ALA Sbjct: 466 PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALAT 525 Query: 2370 PPLGNL----------APFNSGPAASSGLLGLATSVLPTTTVVQTAGPGRPLPQRPMPDQ 2419 PPL L APF+ P+AS + LAT P A P +P P P Sbjct: 526 PPLQALPSPPASFPGQAPFS--PSASLPMSPLATP--PPQAPPVLAAPLLQVP--PSPPA 579 Query: 2420 TNTSTAGTTDPVPGPPTEPLGDKVSSERKPVAGPTSSSNDALKNLKALKTTVPALLGGQF 2479 + T A P PGP T G +++ P P S + + + L G Sbjct: 580 SPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPS------------STLSG-- 625 Query: 2480 LPFPLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNPMIPQTLIGLLPNALLQPPP 2539 P G + A P+ Y G + G P P + A P Sbjct: 626 -----PDLAGHSSSATSTPEELRGYDS---GPEGGAAASPP--PDAELAACHPAAWSRGP 675 Query: 2540 QPPEPTATAPPKP-PELPAPGEGEAGEVDELLTGSTGISTVDVTH-RYLCRQCKMAFD-G 2596 PP AP P P PA G G A G+ T+ T A D G Sbjct: 676 APPLAFRGAPGAPLPWPPATGPGSA----------DGLCTIYETEGPESATPAPGALDPG 725 Query: 2597 EAPATAHQRSFCFFGRGSGGSMPPPLR---VPICTYHCLACEVLLSGREALASHLRSSAH 2653 +P T+ ++ G G+ P R +P+ + LLS LA+ A Sbjct: 726 PSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAA--AEGAA 783 Query: 2654 RRKAAPPQGGPPISITNAATAASAAVAFAKEEARLPHTDSNPKTTTTST 2702 P G +T A AA + + L D + + T+ T Sbjct: 784 GGSGGGPGGAEGGGVTGGARAALSDAELGRWAELLSPLDESRASITSVT 832 Score = 46.6 bits (109), Expect = 3e-04 Identities = 50/180 (27%), Positives = 63/180 (35%), Gaps = 62/180 (34%) Query: 2054 TPGGVPSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAP---------AFPYPT 2104 +P P P PP A P L K P +AP A P P Sbjct: 492 SPSATPPPQAPPPLAAPPLQLAK----------------PPPQAPPALATPPLQALPSPP 535 Query: 2105 ATLASGPQPFLP----PGKEATTPTPEPP----LPLL--PPPPPSEE--EGPEEPPKASP 2152 A+ G PF P P TP P+ P PLL PP PP+ + P PP P Sbjct: 536 ASF-PGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGP 594 Query: 2153 E----------------------SEACSLSAGDLSDSSASSLAEPESPGAGGTSGGPGGG 2190 + S + +LS DL+ S+S+ + PE G GP GG Sbjct: 595 DTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEE--LRGYDSGPEGG 652 Score = 43.9 bits (102), Expect = 0.002 Identities = 46/153 (30%), Positives = 60/153 (39%), Gaps = 31/153 (20%) Query: 1455 PFLSPPPPPLDLHRFPAPLFTPPVLPPFPLVPESLLKLQQQQLLLPFYLHDLKVGPKLTL 1514 PF PP PP+ AP F+PP PP + P + Q L L+V P Sbjct: 439 PFSPPPSPPVQ-----AP-FSPPASPP--VSPSATPPSQAPPSLAA---PPLQVPP---- 483 Query: 1515 AGPAPVLSLPAATPPPPPQPPKA----ELAEREWERPPMAKEGNEAGPSSPPDPLPNEAA 1570 + PA P+ATPPP PP A +LA+ + PP SPP P +A Sbjct: 484 SPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAP 543 Query: 1571 RTAAKALLENFGFELVIQYNEGKQAVPPPPTPP 1603 + + +L A PPP PP Sbjct: 544 FSPSASL------------PMSPLATPPPQAPP 564 Score = 43.1 bits (100), Expect = 0.004 Identities = 68/267 (25%), Positives = 88/267 (32%), Gaps = 71/267 (26%) Query: 2327 PAPEAPPAL-----KAP-----------PATTPASMPLGAAPTLPRLAPVLLSGPALAQP 2370 P+P+AP AL +AP P + PAS P+ + T P AP L+ P L P Sbjct: 423 PSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP 482 Query: 2371 PLGNLAPFNSGPAASSGLLGLATSVLPTTTVVQTAGP----GRPLPQRPMPDQTNTSTAG 2426 P P AS + AT P A P +P PQ P T A Sbjct: 483 P---------SPPASPPMSPSATP--PPQAPPPLAAPPLQLAKPPPQAPPALATPPLQAL 531 Query: 2427 TTDPVPGPPTEPLGDKVSSERKPVAGPTSSSNDALKNLKALKTTVPALLGGQFLPFPLPP 2486 + P P P S P+A P + P +L L P Sbjct: 532 PSPPASFPGQAPFSPSASLPMSPLATPPPQA--------------PPVLAAPLLQVP--- 574 Query: 2487 AGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNPMI--PQTLIG--LLPNALLQPPPQPP 2542 +PPA P LQ P P P T + L AL PP PP Sbjct: 575 ---PSPPA--SPTLQA--------------PRRPPTPGPDTSVSGPRLTLALAPGPPPPP 615 Query: 2543 EPTATAPPKPPELPAPGEGEAGEVDEL 2569 + ++ P+L +EL Sbjct: 616 SRSPSSTLSGPDLAGHSSSATSTPEEL 642 Score = 42.7 bits (99), Expect = 0.005 Identities = 38/116 (32%), Positives = 46/116 (39%), Gaps = 16/116 (13%) Query: 605 PLGLPPGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRPDKPLEAQLLL 664 PL PP P PP P SPP P +PLA P + L LL Sbjct: 388 PLATPPPQAPPALALPPLQAPPSPPA----------SPPLSPLATPSPQAPNALAVHLLQ 437 Query: 665 NGFHHVGAPARKFPTSAPGS--LSPDAHLPPSQL---LGSSSDSLPTSPPPDDSLS 715 F +P + P S P S +SP A PPSQ L + +P SPP +S Sbjct: 438 APFSPPPSPPVQAPFSPPASPPVSPSA-TPPSQAPPSLAAPPLQVPPSPPASPPMS 492 Score = 41.6 bits (96), Expect = 0.011 Identities = 79/312 (25%), Positives = 103/312 (33%), Gaps = 64/312 (20%) Query: 1862 PAGPEGPLPE------PPDGEELSQAEATKAGGKEPEEKATPSPSPAHTCDQC----AIS 1911 PA P P P+ PP + A G ATPSPS A A Sbjct: 266 PAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATP 325 Query: 1912 FSSQDLLTSHRRLHFLPSLQPSAPPQLLDLPLLVFGERNPLVAATSPMPGPPLKRKHE-- 1969 SS L P PSAPP L LP P AT+ + P L+ H Sbjct: 326 HSSSLTCQLATPLPLAPP-SPSAPPSLQTLPS---PPATPPSQATTSLGSPTLQATHSFL 381 Query: 1970 -DGSLSPTGSEAGGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEV 2028 LSP + PP + P Q ++P L S + Sbjct: 382 PSPPLSPLAT---------PPPQAPPALALPPLQAPP-----SPPASPPLSPLATPSPQA 427 Query: 2029 --GLKKRVVQVWFQNTRARERKGQFRSTPGGVP-SPAVKPPATATPASLPKFNLLLGKVD 2085 L ++Q F + + F S P P SP+ PP+ A P+ Sbjct: 428 PNALAVHLLQAPFSPPPSPPVQAPF-SPPASPPVSPSATPPSQAPPSLA----------- 475 Query: 2086 DGTGREAPKREAPAFPYPTATLASGPQPFLPPGKEATTPTPEPPLPLLPPPPPSEEEGPE 2145 AP + P P P PP + TP P+ P PL PP + P+ Sbjct: 476 ------APPLQVPPSP-----------PASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQ 518 Query: 2146 EPPK-ASPESEA 2156 PP A+P +A Sbjct: 519 APPALATPPLQA 530 Score = 41.6 bits (96), Expect = 0.011 Identities = 36/135 (26%), Positives = 50/135 (37%), Gaps = 13/135 (9%) Query: 2058 VPSPAVKPPATATPA----SLPKFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQP 2113 +PSP PP+ AT + +L + L P + PA P P P Sbjct: 354 LPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-P 412 Query: 2114 FLPPGKEATTPTPEPPLPL--------LPPPPPSEEEGPEEPPKASPESEACSLSAGDLS 2165 PP TP+P+ P L PPP + P PP + P S + + + Sbjct: 413 ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 472 Query: 2166 DSSASSLAEPESPGA 2180 +A L P SP A Sbjct: 473 SLAAPPLQVPPSPPA 487 Score = 40.4 bits (93), Expect = 0.024 Identities = 39/123 (31%), Positives = 45/123 (36%), Gaps = 19/123 (15%) Query: 605 PLGLPPGLMGPG---PPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRPDKPLEAQ 661 P PP L P PP PP + P SP P L P LA P P P Sbjct: 467 PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKP--PPQAP--PA 522 Query: 662 LLLNGFHHVGAPARKFPTSAPGSLSPDAHLPPSQL----------LGSSSDSLPTSPPPD 711 L + +P FP AP SP A LP S L L + +P SPP Sbjct: 523 LATPPLQALPSPPASFPGQAP--FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPAS 580 Query: 712 DSL 714 +L Sbjct: 581 PTL 583 Score = 40.0 bits (92), Expect = 0.031 Identities = 71/288 (24%), Positives = 91/288 (31%), Gaps = 34/288 (11%) Query: 1453 GLPFLSPP---PPPLDLHRFPAPLFTPPVLPPFPLVPESLLKLQQQQLLLPFYLHD---- 1505 GL L PP PP D PL + P+ P P S Q LP H Sbjct: 276 GLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP----SAALQSQAPPTLPATPHSSSLT 331 Query: 1506 LKVGPKLTLAGPAPVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPSSPPDPL 1565 ++ L LA P+P T P PP P ++ P + + PS P PL Sbjct: 332 CQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGS--PTLQATHSFLPSPPLSPL 389 Query: 1566 PNEAARTAAKALLENFGFELVIQYNEGKQAVPPPPTPPPPEALGGGDKLACGACGKLFSN 1625 + L QA P PP PP L A A Sbjct: 390 ATPPPQAPPALALPPL------------QAPPSPPASPPLSPLATPSPQAPNALAVHLLQ 437 Query: 1626 MLILKTHEEHVHRRFLPFEA--LSRYAAQFRKSYDSLY-PPLAEPPKPPDGSLDSPV--- 1679 V F P + +S A ++ SL PPL PP PP SP Sbjct: 438 APFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP 497 Query: 1680 -PHLGPPFLVPEPEAGGTRAPEERSRAGGHWPIEEEESSRGNLPPLVP 1726 P PP P + + P + A P++ S + P P Sbjct: 498 PPQAPPPLAAPPLQL--AKPPPQAPPALATPPLQALPSPPASFPGQAP 543 Score = 40.0 bits (92), Expect = 0.031 Identities = 42/146 (28%), Positives = 56/146 (38%), Gaps = 26/146 (17%) Query: 2049 GQFRSTPGGVPSP--AVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAFPYPTAT 2106 G S+P PSP A++ A T + P + L ++ P AP P + Sbjct: 297 GPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQL------ATPLPLAPPSPSAPPS 350 Query: 2107 LASGPQPFLPPGKEATT----PT--------PEPPLPLLPPPPPSEEEGPEEPPKASPES 2154 L + P P P +ATT PT P PPL L PPP PP +P S Sbjct: 351 LQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPS 410 Query: 2155 EACSLSAGDLSDSSASSLAEPESPGA 2180 S L+ S P++P A Sbjct: 411 PPASPPLSPLATPS------PQAPNA 430 Score = 38.9 bits (89), Expect = 0.070 Identities = 84/322 (26%), Positives = 107/322 (33%), Gaps = 77/322 (23%) Query: 2328 APEAPPALKA------PPATTPASMPLGAAPTLPRLAPVLLSGPALAQPPLGNLAPFNSG 2381 AP A P A P + PAS AP +P +S P A G P G Sbjct: 74 APRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRAS---GTTRP---G 127 Query: 2382 PAASSGLL---------GLAT-----SVLPTTTVVQTAGP--GRPLPQRPMPDQTNTSTA 2425 P GL G AT S L T+GP G P P + + Sbjct: 128 PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEV 187 Query: 2426 GTTDPVPG----PPTEPLGDKVSS-------------ERKPVAGPTSSSNDALKNLKALK 2468 G P P PPTE VSS R+P AG A ++L + Sbjct: 188 GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGG-GLQRPASRSLSSSA 246 Query: 2469 TTV--PALLGGQFLPFPLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFP-MNPMIPQT 2525 T + PA G P PA + P LQ Q+ +K P + P+ Sbjct: 247 TPLSSPARSGPSARGTPRAPAHPSQPKP---KGLQALRPPQVTPPRKDAAPALGPLSSSP 303 Query: 2526 LIGLLPNALLQ---PPPQPPEP------------------TATAPPKPPELPAPGEGEAG 2564 L P+A LQ PP P P + +APP LP+P Sbjct: 304 LATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPS 363 Query: 2565 EVDELLTGSTGISTVDVTHRYL 2586 + T S G T+ TH +L Sbjct: 364 QA----TTSLGSPTLQATHSFL 381 Score = 38.9 bits (89), Expect = 0.070 Identities = 70/284 (24%), Positives = 95/284 (33%), Gaps = 69/284 (24%) Query: 1420 EGPERSQEEPKEGETEGEVGTEKKGPDTSGFIS--GLPFLSPPPPPLD--LHRFPAPLFT 1475 EGP +S E T ++ P G + LS PL P+ T Sbjct: 203 EGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGT 262 Query: 1476 P--PVLPPFPLVPESLLKLQQQQLLLPFYLHDLKVGPKLT--LAGPAPVLSLPAATPPPP 1531 P P P P P+ L L+ Q+ P +GP + LA P+P +L + PP Sbjct: 263 PRAPAHPSQPK-PKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTL 321 Query: 1532 PQPPKAELAEREWERP-PMAKEGNEAGPSSPPDPLPNEAARTAAKALLENFGFELVIQYN 1590 P P + + P P+A PS+PP Sbjct: 322 PATPHSSSLTCQLATPLPLAPPS----PSAPPS--------------------------- 350 Query: 1591 EGKQAVPPPPTPPPPEALGGGDKLACGACGKLFSNMLILKTHEEHVHRRFLPFEALSRYA 1650 Q +P PP PP +A + + TH FLP LS A Sbjct: 351 --LQTLPSPPATPPSQATTS------------LGSPTLQATHS------FLPSPPLSPLA 390 Query: 1651 AQFRKSYDSL-YPPLAEPPKPPDGSLDSPVPHLGPPFLVPEPEA 1693 ++ +L PPL PP PP P L P P P+A Sbjct: 391 TPPPQAPPALALPPLQAPPSPPAS------PPLS-PLATPSPQA 427 Score = 37.0 bits (84), Expect = 0.26 Identities = 49/188 (26%), Positives = 67/188 (35%), Gaps = 41/188 (21%) Query: 1471 APLFTPPVLPPFPLVPESLLKLQQQQLLLPFYLHDLKV---GPKLTLAGPAPVLSLPAAT 1527 +PL TPP P P++ LL++ P + GP +++GP L+L Sbjct: 553 SPLATPPPQAP-PVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP 611 Query: 1528 PPPPPQPPKAELA-------EREWERPPMAKEGNEAGP------SSPPD----------- 1563 PPPP + P + L+ P G ++GP S PPD Sbjct: 612 PPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAW 671 Query: 1564 ---PLPNEAARTAAKALLE--------NFGFELVIQYNEGKQAVPPPP--TPPPPEALGG 1610 P P A R A A L + I EG ++ P P P P Sbjct: 672 SRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTS 731 Query: 1611 GDKLACGA 1618 G K A GA Sbjct: 732 GGKAAAGA 739 Score = 36.2 bits (82), Expect = 0.45 Identities = 29/95 (30%), Positives = 39/95 (41%), Gaps = 18/95 (18%) Query: 1213 SLYFLLSPLEGPNLTPEASP-DPLPEPPLASVEVPDKPSGSPGQ--------PPSPAPSP 1263 +++ L +P P P +P P PP++ P PS +P PPSP SP Sbjct: 432 AVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATP--PSQAPPSLAAPPLQVPPSPPASP 489 Query: 1264 VPEPDAQAEDVAPPPTMAEEEEGTTGELRSAEPAP 1298 P A APPP A L+ A+P P Sbjct: 490 PMSPSATPPPQAPPPLAAP-------PLQLAKPPP 517 Score = 35.8 bits (81), Expect = 0.59 Identities = 81/370 (21%), Positives = 117/370 (31%), Gaps = 43/370 (11%) Query: 72 EIGEPQEGPDCGHFPPNDPGVEKDKEQEEEEEGLPPMDLSNHLFFTAGGEAYLVAKLSLP 131 E+G P+ P PP + G K E P + GG ++ Sbjct: 186 EVGLPRPAPSARPRPPTE-GPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS 244 Query: 132 GGSELLLPKGFPWGEAGIKEEPSLPFLAYPPPSHLTALHIQHGFDPIQGFSSS-DQILSH 190 + L P G P+ P + P P L AL P + + + + S Sbjct: 245 SATPLSSPARSGPSARGTPRAPAHP--SQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS 302 Query: 191 DTSAPSPAACEERHGAFWSYQLAPNPPGDPKDGPMGNSGGNHVAVFWLCLLCRLGFSKPQ 250 + PSP+A + Q P P P L C+L P Sbjct: 303 PLATPSPSAALQS-------QAPPTLPATPHSSS---------------LTCQLATPLPL 340 Query: 251 AFMDHTQSHGVKLTPAQYQGLSGSPAVLQEGDEGCKALISFLEPKLPARPSSDIPLDNSS 310 A + ++ P+ S A G +A SFL P P P + P Sbjct: 341 APPSPSAPPSLQTLPSP-PATPPSQATTSLGSPTLQATHSFL-PSPPLSPLATPPPQAPP 398 Query: 311 TVNMEANVAQTED--GPPEAEVQALILLDEEVMAL----SPPSPPTATWDPSPTQAKESP 364 + + A PP + + +A+ +P SPP + P QA SP Sbjct: 399 ALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP----PVQAPFSP 454 Query: 365 VAAGEAGPDWFPEGQEEDGGLCPPLNQSSPTSKEGGTLPAPVGSPEDPSDPP---QPYRL 421 A+ P P Q PPL P S +P +P + PP P +L Sbjct: 455 PASPPVSPSATPPSQAPPSLAAPPL--QVPPSPPASPPMSPSATPPPQAPPPLAAPPLQL 512 Query: 422 ADDYTPAPAA 431 A AP A Sbjct: 513 AKPPPQAPPA 522 Score = 35.0 bits (79), Expect = 1.0 Identities = 24/66 (36%), Positives = 32/66 (48%), Gaps = 8/66 (12%) Query: 1221 LEGPNLTPEASPDPLPEPPLA--SVEVPDKPSGSPGQPPSPAPSPVPEPDAQAEDV---- 1274 L P L+P A+P P P LA ++ P P SP P PSP P+A A + Sbjct: 381 LPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSP-QAPNALAVHLLQAP 439 Query: 1275 -APPPT 1279 +PPP+ Sbjct: 440 FSPPPS 445 Score = 35.0 bits (79), Expect = 1.0 Identities = 24/68 (35%), Positives = 28/68 (41%), Gaps = 6/68 (8%) Query: 1219 SPLEGPNLTPEASPDPLPEPPLASVEVPDKPSGSPGQPP-----SPAPSPVPEPDAQAED 1273 SP P L+P A+P P P +V + P P PP SP SP P A Sbjct: 410 SPPASPPLSPLATPSP-QAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS 468 Query: 1274 VAPPPTMA 1281 APP A Sbjct: 469 QAPPSLAA 476 Score = 34.7 bits (78), Expect = 1.3 Identities = 29/105 (27%), Positives = 39/105 (37%), Gaps = 25/105 (23%) Query: 1219 SPLEGPNLTPEASPDPLPEPPLAS--VEVPDKPSGSPG-----QPPSP------------ 1259 SP ++P A+P P P LA+ ++VP P SP +PP+P Sbjct: 545 SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLT 604 Query: 1260 ---APSPVPEPDAQAEDVAPPPTMAEEEEGTTG---ELRSAEPAP 1298 AP P P P P +A T ELR + P Sbjct: 605 LALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGP 649 Score = 33.9 bits (76), Expect = 2.2 Identities = 25/81 (30%), Positives = 32/81 (39%), Gaps = 22/81 (27%) Query: 1219 SPLEGPNLTPEASPDPLPEPPLASVEV---------------------PDKPSGSPGQPP 1257 SP P ++P A+P P PPLA+ + P P+ PGQ P Sbjct: 484 SPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAP 543 Query: 1258 -SPAPSPVPEPDAQAEDVAPP 1277 SP+ S P A APP Sbjct: 544 FSPSASLPMSPLATPPPQAPP 564 Score = 33.5 bits (75), Expect = 2.9 Identities = 24/75 (32%), Positives = 30/75 (40%), Gaps = 15/75 (20%) Query: 1219 SPLEGPNLTPEASPD----------PLPEPPLASVEVPDKPSGSPGQPPSPAPSPVPEPD 1268 SP P ++P A+P PL PP P PS + PP AP P+ P Sbjct: 453 SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSAT---PPPQAPPPLAAPP 509 Query: 1269 AQAEDVAP--PPTMA 1281 Q P PP +A Sbjct: 510 LQLAKPPPQAPPALA 524 Score = 32.7 bits (73), Expect = 5.0 Identities = 48/183 (26%), Positives = 57/183 (31%), Gaps = 42/183 (22%) Query: 548 SPPEASLPPSAGDKEPKTKSSWQCKVCSYETNISRNLRIHMTSEKHMQNVLMLHQ-GLPL 606 +PP +LPP P S L T N L +H P Sbjct: 396 APPALALPPLQAPPSPPA---------------SPPLSPLATPSPQAPNALAVHLLQAPF 440 Query: 607 GLPPGLMGPGPPPPPGATPTSPPELFQYFGPQALGQPQ-----TPLAGPGLRPD------ 655 PP P PP + P SP P +L P +P A P + P Sbjct: 441 SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 500 Query: 656 --KPLEAQLLLNGFHHVGAPARKFPTSAPGSLSPDAHLPPSQLLGSSSDSLPTSPPPDDS 713 PL A L K P AP +L+ PP Q L S S P P S Sbjct: 501 APPPLAAPPL---------QLAKPPPQAPPALA----TPPLQALPSPPASFPGQAPFSPS 547 Query: 714 LSL 716 SL Sbjct: 548 ASL 550 Score = 32.7 bits (73), Expect = 5.0 Identities = 51/195 (26%), Positives = 65/195 (33%), Gaps = 61/195 (31%) Query: 2060 SPAVKPPATATPASLPKFNLLLGKVDDGTGR--------EAPKREAPAFPYPTATLAS-- 2109 +P PP + +P+S L G T P+ A A P P A LA+ Sbjct: 608 APGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACH 667 Query: 2110 ------GPQPFLPPGKEATTPTPEPPLPLLPPPPPS---------EEEGPEEP------- 2147 GP P L A P PLP P P E EGPE Sbjct: 668 PAAWSRGPAPPL-----AFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGAL 722 Query: 2148 -PKASPESEACSLSAGDLSDSSASSLAEP---ESP--------------------GAGGT 2183 P SP + +AG + +S+ S + E P A G Sbjct: 723 DPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGA 782 Query: 2184 SGGPGGGTGVPDGMG 2198 +GG GGG G +G G Sbjct: 783 AGGSGGGPGGAEGGG 797 Score = 32.0 bits (71), Expect = 8.5 Identities = 63/257 (24%), Positives = 87/257 (33%), Gaps = 56/257 (21%) Query: 2326 APAPEAPPALKAPPATTPA--SMPLGAAPTLPRLAPVLLSGPALAQPPLGNLAPFNSGPA 2383 A A PA +AP TP P P P VL + A+ + PL A Sbjct: 10 AGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAG------ 63 Query: 2384 ASSGLLGLATSVLPTTTVVQTAGPGRPLPQRPMPDQTNTSTAGTT--DPVPGPPTEPLGD 2441 G+ + +P + AGP T +AGT+ +P PP G+ Sbjct: 64 ------GIGGATIPESA--PRAGP--------------TRSAGTSSRNPASRPPASGRGE 101 Query: 2442 KVSSERKPVAGPTSSSNDALKNLKALKTTVPALLGGQFLPFPLPP--AGGTAPPAVFGPQ 2499 + + GP SS +A TT P LG + L A G A A Sbjct: 102 RAPPAKNTSPGPVSSPG------RASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSA 155 Query: 2500 LQGAYFQQLYGMKKGLFPMNPMIPQ-----TLIGL---LPNALLQPPPQPPEPT------ 2545 L + G G P M + T +GL P+A +PP + P + Sbjct: 156 LSAGARRDTSGPTPGT-PSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 214 Query: 2546 -ATAPPKPPELPAPGEG 2561 +T P P P G Sbjct: 215 HSTTEPSPAARRRPSAG 231 >gi|110832843 TBP-associated factor 4 [Homo sapiens] Length = 1085 Score = 62.8 bits (151), Expect = 4e-09 Identities = 74/252 (29%), Positives = 86/252 (34%), Gaps = 42/252 (16%) Query: 2328 APEAPPALKAPPATTPASMPLGAAPTLPRLAPVLLSGPALAQPPLGNLAPFNSGPAASSG 2387 APE PPA +A P P P PR P++ +GPA PP L P G A S Sbjct: 86 APEPPPAGRARPGGGGPQRP---GPPSPR-RPLVPAGPA---PPAAKLRPPPEGSAGSCA 138 Query: 2388 LLGLATSVLPTTTVVQTAGPGRPLPQRPMPDQTNTSTAGTTDPVPGP-PTEPLGDKVSSE 2446 + A +V AGP P P P + A P PGP P G Sbjct: 139 PVPAAAAV--------AAGP-EPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKP 189 Query: 2447 RKPVAGPTSSSNDALKNLKALKTTVPALLG---GQFLPFPLPPAGGT-----------AP 2492 P A T + + AL N +L+ LP P P A GT AP Sbjct: 190 AGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAP 249 Query: 2493 PAVFGPQLQGAYFQQLYGMKKGLFPMNPMIPQTLIGLLPNALLQPPPQPPEPTATAPPKP 2552 PA P A P P P L +PP P P AP P Sbjct: 250 PAPAAPSPPAA-----------PAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVP 298 Query: 2553 PELPAPGEGEAG 2564 P A G AG Sbjct: 299 PPAAAQNGGSAG 310 Score = 53.9 bits (128), Expect = 2e-06 Identities = 95/407 (23%), Positives = 133/407 (32%), Gaps = 86/407 (21%) Query: 2061 PAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQPFLPPGKE 2120 P KP A T P F G AP APA P P A A P Sbjct: 227 PLPKPAAPGTVIQTPPF----------VGAAAPP--APAAPSPPAAPA--------PAAP 266 Query: 2121 ATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESEACSLSAGDLSDSSASSLAEPESPGA 2180 A P P PP P PP GP A P A + ++ A +P A Sbjct: 267 AAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQ-------NGGSAGAAPAPAPAA 319 Query: 2181 GGTSG-----GPGGGTGVPDGMGQRRYRTQMSSLQLKIMKACYEAYRT------------ 2223 GG +G GPG P G + + ++++A A +T Sbjct: 320 GGPAGVSGQPGPGAAAAAP-APGVK------AESPKRVVQAAPPAAQTLAASGPASTAAS 372 Query: 2224 ----PTMQEC---------EVLGEEIGLPKRVIQVWFQNARAKEKKAKLQGTAAGSTGGS 2270 PTMQ G GLPK A + T +G Sbjct: 373 MVIGPTMQGALPSPAAVPPPAPGTPTGLPKGA-----AGAVTQSLSRTPTATTSGIRATL 427 Query: 2271 SEGLLAAQRTDCPYCDVKYDFYVSCRGHLFSRQ---HLAKLKEAVRAQLKSESKCY---D 2324 + +LA + P + G + R L + + AQ+++++ Sbjct: 428 TPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTT 487 Query: 2325 LAPAPEAPPALKAPPATTPASMPLGAAPTLPRLAP-VLLSGPALAQPPLGNLAPFNSGPA 2383 +AP P P + APP G ++ P ++ + AQ + A P Sbjct: 488 MAPRPATPTS--APPVQISTVQAPGTPIIARQVTPTTIIKQVSQAQTTVQPSATLQRSPG 545 Query: 2384 ASSGLL---GLATSVLPTTTVVQTAGPGRPLPQRPMPDQTNTSTAGT 2427 L+ T+ L T T VQT PQR +P T TS+A T Sbjct: 546 VQPQLVLGGAAQTASLGTATAVQTG-----TPQRTVPGATTTSSAAT 587 Score = 45.4 bits (106), Expect = 7e-04 Identities = 80/283 (28%), Positives = 100/283 (35%), Gaps = 45/283 (15%) Query: 2326 APAPEAPPALKAPPATTPASMPLGAAPTLPRLAPVLLSGPALAQPPLGNLAPFNSGPAAS 2385 APA A PA A A P P P +GP AQ G+ A NS AA+ Sbjct: 153 APAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAA 212 Query: 2386 ----------SGLLGLATSVLPTTTVVQT----AGPGRPLPQRPMPDQTNTSTAGTTDPV 2431 + LL L P TV+QT P P P P A P Sbjct: 213 PAVSLVNNGPAALLPLPKPAAP-GTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPP 271 Query: 2432 PGPPTEPLGDKVSSERKP--VAGPTSSSNDALKNLKALKTTVPALLGGQ--FLPFPLPPA 2487 P PP + R P AGP +++ A+ A GG P P P A Sbjct: 272 PPPPA-----PATLARPPGHPAGPPTAA-------PAVPPPAAAQNGGSAGAAPAPAPAA 319 Query: 2488 GGTAPPAVFG-PQLQGAYFQQLYGMK----KGLFPMNPMIPQTLIGLLP-----NALLQP 2537 GG P V G P A G+K K + P QTL P + ++ P Sbjct: 320 GG--PAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGP 377 Query: 2538 PPQP--PEPTATAPPKPPELPAPGEGEAGEVDELLTGSTGIST 2578 Q P P A PP P +G AG V + L+ + +T Sbjct: 378 TMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATT 420 Score = 44.7 bits (104), Expect = 0.001 Identities = 42/146 (28%), Positives = 52/146 (35%), Gaps = 19/146 (13%) Query: 2054 TPGGVPSPAVKPPATATPASLPKFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQP 2113 +P G PA P + P+ GR P P P P S +P Sbjct: 66 SPAGAAGAGPAAPAEGAPGAAPE--------PPPAGRARPGGGGPQRPGPP----SPRRP 113 Query: 2114 FLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESEACSLSAGDLSDSSASSLA 2173 +P G P P P L PPP S P A+ + AG + ++LA Sbjct: 114 LVPAG-----PAP-PAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALA 167 Query: 2174 EPESPGAG-GTSGGPGGGTGVPDGMG 2198 PG G G GPG G G P G G Sbjct: 168 ARAGPGPGPGPGPGPGPGPGKPAGPG 193 Score = 43.1 bits (100), Expect = 0.004 Identities = 81/323 (25%), Positives = 108/323 (33%), Gaps = 72/323 (22%) Query: 2326 APAPEAPPALKAPPATTPASMPLGAAPTLPRLAPVLLSGPALAQPPL---------GNL- 2375 APA +PPA AP A A P AP P +GP A P + G+ Sbjct: 251 APAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAG 310 Query: 2376 -----APFNSGPAASSGLLGLATSVLPTTTVVQTAGPGRPLPQRPMPDQTNT-------- 2422 AP GPA SG G + V+ P R + P QT Sbjct: 311 AAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTA 370 Query: 2423 --------------STAGTTDPVPGPPTE-PLGDKVSSERKPVAGPTSSSNDALKNLKAL 2467 S A P PG PT P G + + PT++++ ++A Sbjct: 371 ASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTS----GIRA- 425 Query: 2468 KTTVPALLGGQFLPFPLPPAGGTAPPAVFGPQLQGAYFQQLYGMKKGLFPMNPMIPQTLI 2527 T P +L + P PP P + QL L + G M P Q L Sbjct: 426 -TLTPTVLAPR---LPQPPQN---PTNIQNFQLPPG--MVLVRSENGQLLMIPQ--QALA 474 Query: 2528 GLLPNALLQP----PPQPPEPTATAPPKPPELPAPGEGEAGEVDELLTGSTGISTVDVTH 2583 + A QP P+P PT+ P + + APG T I VT Sbjct: 475 QMQAQAHAQPQTTMAPRPATPTSAPPVQISTVQAPG--------------TPIIARQVTP 520 Query: 2584 RYLCRQCKMAFDGEAPATAHQRS 2606 + +Q A P+ QRS Sbjct: 521 TTIIKQVSQAQTTVQPSATLQRS 543 Score = 42.0 bits (97), Expect = 0.008 Identities = 32/112 (28%), Positives = 41/112 (36%), Gaps = 18/112 (16%) Query: 614 GPGPPPPPGATPTSPPELFQYFGPQALGQPQTPLAGPGLRPDKP--------LEAQLLLN 665 GP P P A P P L GP G P GPG P KP L L Sbjct: 149 GPEPAPAGPAKPAGPAALAARAGP---GPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALL 205 Query: 666 GFHHVGAPARKFPTSAPGSL-------SPDAHLPPSQLLGSSSDSLPTSPPP 710 HH APA + P +L +P + +G+++ P +P P Sbjct: 206 NSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSP 257 Score = 37.4 bits (85), Expect = 0.20 Identities = 34/94 (36%), Positives = 39/94 (41%), Gaps = 18/94 (19%) Query: 1515 AGPAPVLSLPAATPPPPPQPPKAELAEREWERPPMAKEGNEAGPSS------PPDPLPNE 1568 A PAP + PAA PPPPP P A LA RPP G+ AGP + PP N Sbjct: 259 AAPAP--AAPAAAPPPPP-PAPATLA-----RPP----GHPAGPPTAAPAVPPPAAAQNG 306 Query: 1569 AARTAAKALLENFGFELVIQYNEGKQAVPPPPTP 1602 + AA A G + G A P P Sbjct: 307 GSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAP 340 Score = 36.6 bits (83), Expect = 0.35 Identities = 30/94 (31%), Positives = 33/94 (35%), Gaps = 19/94 (20%) Query: 1223 GPNLTPEASPDPLPEPPLASVEVPDKPSGSPGQPPSP-------APSPV-----PEPDAQ 1270 GP E +P PEPP A P PPSP P+P P P+ Sbjct: 74 GPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGS 133 Query: 1271 AEDVAPPPTMAEEEEGTTGELRSAEPAPADSRHP 1304 A AP P A G EPAPA P Sbjct: 134 AGSCAPVPAAAAVAAG-------PEPAPAGPAKP 160 Score = 35.8 bits (81), Expect = 0.59 Identities = 71/288 (24%), Positives = 81/288 (28%), Gaps = 76/288 (26%) Query: 1432 GETEGEVGTEKKGPDTSGFISGLPFLSPPPPPLDLHR--FPAPLFTPPVLPPFPLVPESL 1489 G G G P G P +P PPP R P P P PLVP Sbjct: 65 GSPAGAAGAGPAAP-----AEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVP--- 116 Query: 1490 LKLQQQQLLLPFYLHDLKVGPKLTLAGPAPVLSLPAATPPPPPQPPKAELAEREWERPPM 1549 AGPAP PAA PPP+ A P Sbjct: 117 -------------------------AGPAP----PAAKLRPPPEGSAGSCA------PVP 141 Query: 1550 AKEGNEAGPSSPPDPLPNEAARTAAKALLENFGFELVIQYNEGKQAVPPPPTPPPPEALG 1609 A AGP +P P A+ A A L + P P P P G Sbjct: 142 AAAAVAAGP----EPAPAGPAKPAGPAALA------------ARAGPGPGPGPGPGPGPG 185 Query: 1610 GGDKLACGACGKLFSNMLILKTHEEHVHRRF-----------LPFEALSRYAAQFRKSYD 1658 G GA L + +L +H LP A Q Sbjct: 186 PGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVG 245 Query: 1659 SLYPPLAEPPKPPDGSLDSPVPHLGPPFLVPEPEAGGTRAPEERSRAG 1706 + PP P PP + P PP P P A T A AG Sbjct: 246 AAAPPAPAAPSPPAAPAPA-APAAAPP---PPPPAPATLARPPGHPAG 289 Score = 35.0 bits (79), Expect = 1.0 Identities = 29/105 (27%), Positives = 41/105 (39%), Gaps = 18/105 (17%) Query: 1207 LNEVPSSLYFLLSP------LEGPNLTPEASPDPLPEPPLASVEVPDKPSGSPGQPPSPA 1260 +N P++L L P ++ P A+P P + P P+ +P PP PA Sbjct: 218 VNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAP-PPPPPA 276 Query: 1261 PSPVPEPDAQ------AEDVAPPPTMAEEEEGTTGELRSAEPAPA 1299 P+ + P A PPP A+ G A PAPA Sbjct: 277 PATLARPPGHPAGPPTAAPAVPPPAAAQN-----GGSAGAAPAPA 316 Score = 34.3 bits (77), Expect = 1.7 Identities = 21/75 (28%), Positives = 28/75 (37%), Gaps = 4/75 (5%) Query: 1228 PEASPDPLPEPPLASVEVPDKPSGSPGQPPSPAPSPVPEPDAQAEDVAPPPTMAEEEEGT 1287 P A+P P P P P P+G P P+ P + A P A G Sbjct: 266 PAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGV 325 Query: 1288 TGE----LRSAEPAP 1298 +G+ +A PAP Sbjct: 326 SGQPGPGAAAAAPAP 340 >gi|24497589 aristaless related homeobox [Homo sapiens] Length = 562 Score = 62.8 bits (151), Expect = 4e-09 Identities = 67/247 (27%), Positives = 98/247 (39%), Gaps = 32/247 (12%) Query: 2150 ASPESEACSLSAGDLSDSSASSLAEPESPGAGGT-SGGPGGGTGVPDGM---GQRRYRTQ 2205 A+ + A + G+LS L ++ G G S G+ +G+ QRRYRT Sbjct: 275 AAAAAAAVATEGGELSPKEELLLHPEDAEGKDGEDSVCLSAGSDSEEGLLKRKQRRYRTT 334 Query: 2206 MSSLQLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAKLQGTAAG 2265 +S QL+ ++ ++ P + E L + L + +QVWFQN RAK +K + G Sbjct: 335 FTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKREKAGAQTH 394 Query: 2266 STGGSSEGLLAAQRTDCPYCDVKYDFYVSCRGHLFSRQHLAKLKEAVRAQLKSESKCYDL 2325 G G L+A PY D F H A L A A + + + Sbjct: 395 PPGLPFPGPLSATHPLSPYLDAS----------PFPPHHPA-LDSAWTAAAAAAAAAFPS 443 Query: 2326 APAPEAPPALKAPPATTPASMP--LGAAPTLPRLAPVLLSGPALAQPPLGNL----APFN 2379 P P P + PP+ P + LGAA + PA P G L AP Sbjct: 444 LPPP--PGSASLPPSGAPLGLSTFLGAA---------VFRHPAFISPAFGRLFSTMAPLT 492 Query: 2380 SGPAASS 2386 S A++ Sbjct: 493 SASTAAA 499 Score = 50.1 bits (118), Expect = 3e-05 Identities = 75/319 (23%), Positives = 109/319 (34%), Gaps = 86/319 (26%) Query: 1833 EEEEEEAERGEEEEEVEEEEVEEEQGLEPPAGPEGPLPEPPDGEELSQAEATKAGGKEPE 1892 E++EEE EE+E+ EEE +E+++ EEL + +A +A KEP Sbjct: 224 EDDEEELLEDEEDEDEEEELLEDDE------------------EELLEDDA-RALLKEPR 264 Query: 1893 EKATPSPSPAHTCDQCAISFSSQDLLTSHRRLHFLPSLQPSAPPQLLDLPLLVFGERNPL 1952 + A++ +L L + GE + Sbjct: 265 RCPVAATGAVAAAAAAAVATEGGELSPKEELLLHPEDAEGKD------------GEDSVC 312 Query: 1953 VAATSPMPGPPLKRKHEDGSLSPTGSEAGGGGEGEPPRDKRLRTTILPEQLEILYRWYMQ 2012 ++A S LKRK +R RTT QLE L R + + Sbjct: 313 LSAGSDSEEGLLKRKQ-----------------------RRYRTTFTSYQLEELERAFQK 349 Query: 2013 DSNPTRKMLDCISEEVGLKKRVVQVWFQNTRARERKGQ---FRSTPGGVPSPAVKPPATA 2069 P + ++ + L + VQVWFQN RA+ RK + ++ P G+P P P +A Sbjct: 350 THYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKREKAGAQTHPPGLPFPG---PLSA 406 Query: 2070 TPASLPKFNLLLGKVDDGTGREAPKREAPAFPYPTATLASGPQPFLPPGKEATTPTPEPP 2129 T P PY A+ P L A Sbjct: 407 T--------------------------HPLSPYLDASPFPPHHPALDSAWTAAAAAAAAA 440 Query: 2130 LPLLPPPPPSEEEGPEEPP 2148 P LPPPP S P P Sbjct: 441 FPSLPPPPGSASLPPSGAP 459 Score = 45.1 bits (105), Expect = 0.001 Identities = 27/68 (39%), Positives = 34/68 (50%) Query: 1724 LVPAGRRFSRTKFTEFQTQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQK 1783 L+ +R RT FT +Q + L+ F+ + YP E LA L L V VWFQN R K Sbjct: 323 LLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAK 382 Query: 1784 ARKNACEG 1791 RK G Sbjct: 383 WRKREKAG 390 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.313 0.133 0.409 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 151,903,721 Number of Sequences: 37866 Number of extensions: 10384909 Number of successful extensions: 176510 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 1147 Number of HSP's successfully gapped in prelim test: 2293 Number of HSP's that attempted gapping in prelim test: 60053 Number of HSP's gapped (non-prelim): 87769 length of query: 2706 length of database: 18,247,518 effective HSP length: 120 effective length of query: 2586 effective length of database: 13,703,598 effective search space: 35437504428 effective search space used: 35437504428 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 71 (32.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.