Guide to the Human Genome
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Name: PITX1 Sequence: fasta or formatted (314aa) NCBI GI: 152963644
Description:

paired-like homeodomain transcription factor 1

Referenced in:

Homeobox and Related Proteins
Left-Right Axis
Pituitary

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.0         25           2
 C cysteine            1.6          5           1
 D aspartate           3.5         11           2
 E glutamate           5.4         17           2
 F phenylalanine       3.5         11           2
 G glycine             9.2         29           2
 H histidine           1.3          4           1
 I isoleucine          1.0          3           1
 K lysine              4.8         15           4
 L leucine             7.3         23           1
 M methionine          3.8         12           1
 N asparagine          5.4         17           2
 P proline            10.2         32           6
 Q glutamine           4.5         14           2
 R arginine            6.4         20           2
 S serine             12.7         40           2
 T threonine           4.1         13           1
 V valine              2.5          8           1
 W tryptophan          1.3          4           1
 Y tyrosine            3.5         11           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   paired-like homeodomain transcription factor 1 [Hom... 
PITX2                 0.541   paired-like homeodomain transcription factor 2 isofo...
PITX2                 0.537   paired-like homeodomain transcription factor 2 isofo...
PITX2                 0.534   paired-like homeodomain transcription factor 2 isofo...
PITX3                 0.407   paired-like homeodomain 3 
ALX4                  0.144   aristaless-like homeobox 4 
ARX                   0.128   aristaless related homeobox 
ALX1                  0.126   cartilage paired-class homeoprotein 1 
ALX3                  0.124   aristaless-like homeobox 3 
RAX                   0.124   retina and anterior neural fold homeobox 
DRGX                  0.121   dorsal root ganglia homeobox 
OTP                   0.121   PREDICTED: orthopedia homeobox 
OTP                   0.121   orthopedia homeobox 
PRRX2                 0.120   paired related homeobox 2 
PAX7                  0.118   paired box 7 isoform 1 
PAX7                  0.118   paired box 7 isoform 2 
PAX7                  0.118   paired box 7 isoform 3 
PAX3                  0.115   paired box 3 isoform PAX3i 
PAX3                  0.115   paired box 3 isoform PAX3g 
PAX3                  0.115   paired box 3 isoform PAX3h 
PAX3                  0.115   paired box 3 isoform PAX3e 
PAX3                  0.115   paired box 3 isoform PAX3d 
PAX3                  0.115   paired box 3 isoform PAX3 
OTX1                  0.108   orthodenticle homeobox 1 
SHOX2                 0.107   short stature homeobox 2 isoform a 
DMBX1                 0.107   diencephalon/mesencephalon homeobox 1 isoform b [Hom...
DMBX1                 0.107   diencephalon/mesencephalon homeobox 1 isoform a [Hom...
OTX2                  0.105   orthodenticle homeobox 2 isoform b 
OTX2                  0.102   orthodenticle homeobox 2 isoform a 
RAX2                  0.100   retina and anterior neural fold homeobox 2 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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