Guide to the Human Genome
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Search of human proteins with 11119414

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|11119414 transforming, acidic coiled-coil containing protein
2 isoform d [Homo sapiens]
         (1026 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|11119414 transforming, acidic coiled-coil containing protein ...  2029   0.0  
gi|150418009 transforming, acidic coiled-coil containing protein...  1990   0.0  
gi|45827755 transforming, acidic coiled-coil containing protein ...  1986   0.0  
gi|45827753 transforming, acidic coiled-coil containing protein ...  1960   0.0  
gi|170763517 transforming, acidic coiled-coil containing protein...   306   5e-83
gi|226246618 transforming, acidic coiled-coil containing protein...   300   4e-81
gi|170763519 transforming, acidic coiled-coil containing protein...   298   2e-80
gi|5454102 transforming, acidic coiled-coil containing protein 3...   211   3e-54
gi|163965366 nascent polypeptide-associated complex alpha subuni...    80   1e-14
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   79   3e-14
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   79   3e-14
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   79   3e-14
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    79   3e-14
gi|110349719 titin isoform N2-A [Homo sapiens]                         70   8e-12
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    70   8e-12
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     68   5e-11
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    67   7e-11
gi|16554449 zonadhesin isoform 3 [Homo sapiens]                        67   7e-11
gi|27881494 zonadhesin isoform 6 [Homo sapiens]                        67   7e-11
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         64   7e-10
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap...    63   1e-09
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [...    63   1e-09
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap...    63   2e-09
gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]        62   4e-09
gi|91982772 mucin 17 [Homo sapiens]                                    61   5e-09
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    60   8e-09
gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]    60   8e-09
gi|149773456 hypothetical protein LOC643314 [Homo sapiens]             59   2e-08
gi|58530840 desmoplakin isoform I [Homo sapiens]                       59   2e-08
gi|116284392 mucin 2 precursor [Homo sapiens]                          59   3e-08

>gi|11119414 transforming, acidic coiled-coil containing protein 2
            isoform d [Homo sapiens]
          Length = 1026

 Score = 2029 bits (5258), Expect = 0.0
 Identities = 1026/1026 (100%), Positives = 1026/1026 (100%)

Query: 1    MGGSQSLQPAPASDLNLEASEAMSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVS 60
            MGGSQSLQPAPASDLNLEASEAMSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVS
Sbjct: 1    MGGSQSLQPAPASDLNLEASEAMSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVS 60

Query: 61   TQPPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDN 120
            TQPPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDN
Sbjct: 61   TQPPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDN 120

Query: 121  IELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGN 180
            IELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGN
Sbjct: 121  IELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGN 180

Query: 181  PEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESL 240
            PEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESL
Sbjct: 181  PEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESL 240

Query: 241  VPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGR 300
            VPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGR
Sbjct: 241  VPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGR 300

Query: 301  VQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQEN 360
            VQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQEN
Sbjct: 301  VQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQEN 360

Query: 361  PPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKW 420
            PPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKW
Sbjct: 361  PPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKW 420

Query: 421  DDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPA 480
            DDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPA
Sbjct: 421  DDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPA 480

Query: 481  SAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVI 540
            SAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVI
Sbjct: 481  SAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVI 540

Query: 541  SAVVHATDEEKLAVTNQKWTCMTVDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNS 600
            SAVVHATDEEKLAVTNQKWTCMTVDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNS
Sbjct: 541  SAVVHATDEEKLAVTNQKWTCMTVDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNS 600

Query: 601  YEIEYMEKIGSSLPQDDDAPKKQALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEETE 660
            YEIEYMEKIGSSLPQDDDAPKKQALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEETE
Sbjct: 601  YEIEYMEKIGSSLPQDDDAPKKQALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEETE 660

Query: 661  ALVNTAAKNQHPVPRGLAPNQESHLQVPEKSSQKELEAMGLGTPSEAIEITAPEGSFASA 720
            ALVNTAAKNQHPVPRGLAPNQESHLQVPEKSSQKELEAMGLGTPSEAIEITAPEGSFASA
Sbjct: 661  ALVNTAAKNQHPVPRGLAPNQESHLQVPEKSSQKELEAMGLGTPSEAIEITAPEGSFASA 720

Query: 721  DALLSRLAHPVSLCGALDYLEPDLAEKNPPLFAQKLQEELEFAIMRIEALKLARQIALAS 780
            DALLSRLAHPVSLCGALDYLEPDLAEKNPPLFAQKLQEELEFAIMRIEALKLARQIALAS
Sbjct: 721  DALLSRLAHPVSLCGALDYLEPDLAEKNPPLFAQKLQEELEFAIMRIEALKLARQIALAS 780

Query: 781  RSHQDAKREAAHPTDVSISKTALYSRIGTAEVEKPAGLLFQQPDLDSALQIARAEIITKE 840
            RSHQDAKREAAHPTDVSISKTALYSRIGTAEVEKPAGLLFQQPDLDSALQIARAEIITKE
Sbjct: 781  RSHQDAKREAAHPTDVSISKTALYSRIGTAEVEKPAGLLFQQPDLDSALQIARAEIITKE 840

Query: 841  REVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQAL 900
            REVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQAL
Sbjct: 841  REVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQAL 900

Query: 901  ADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAE 960
            ADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAE
Sbjct: 901  ADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAE 960

Query: 961  EKLDRANAEIAQVRGKAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEELTKICDELI 1020
            EKLDRANAEIAQVRGKAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEELTKICDELI
Sbjct: 961  EKLDRANAEIAQVRGKAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEELTKICDELI 1020

Query: 1021 AKMGKS 1026
            AKMGKS
Sbjct: 1021 AKMGKS 1026


>gi|150418009 transforming, acidic coiled-coil containing protein 2
            isoform a [Homo sapiens]
          Length = 2948

 Score = 1990 bits (5155), Expect = 0.0
 Identities = 1008/1018 (99%), Positives = 1009/1018 (99%), Gaps = 6/1018 (0%)

Query: 9    PAPASDLNLEASEAMSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEP 68
            P PA DL+       SSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEP
Sbjct: 1937 PDPAKDLS------RSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEP 1990

Query: 69   GCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQ 128
            GCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQ
Sbjct: 1991 GCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQ 2050

Query: 129  TLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAP 188
            TLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAP
Sbjct: 2051 TLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAP 2110

Query: 189  DAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLA 248
            DAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLA
Sbjct: 2111 DAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLA 2170

Query: 249  SETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVG 308
            SETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVG
Sbjct: 2171 SETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVG 2230

Query: 309  RKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIG 368
            RKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIG
Sbjct: 2231 RKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIG 2290

Query: 369  KKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPF 428
            KKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPF
Sbjct: 2291 KKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPF 2350

Query: 429  SSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGV 488
            SSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGV
Sbjct: 2351 SSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGV 2410

Query: 489  DGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATD 548
            DGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATD
Sbjct: 2411 DGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATD 2470

Query: 549  EEKLAVTNQKWTCMTVDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEK 608
            EEKLAVTNQKWTCMTVDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEK
Sbjct: 2471 EEKLAVTNQKWTCMTVDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEK 2530

Query: 609  IGSSLPQDDDAPKKQALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAK 668
            IGSSLPQDDDAPKKQALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAK
Sbjct: 2531 IGSSLPQDDDAPKKQALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAK 2590

Query: 669  NQHPVPRGLAPNQESHLQVPEKSSQKELEAMGLGTPSEAIEITAPEGSFASADALLSRLA 728
            NQHPVPRGLAPNQESHLQVPEKSSQKELEAMGLGTPSEAIEITAPEGSFASADALLSRLA
Sbjct: 2591 NQHPVPRGLAPNQESHLQVPEKSSQKELEAMGLGTPSEAIEITAPEGSFASADALLSRLA 2650

Query: 729  HPVSLCGALDYLEPDLAEKNPPLFAQKLQEELEFAIMRIEALKLARQIALASRSHQDAKR 788
            HPVSLCGALDYLEPDLAEKNPPLFAQKLQEELEFAIMRIEALKLARQIALASRSHQDAKR
Sbjct: 2651 HPVSLCGALDYLEPDLAEKNPPLFAQKLQEELEFAIMRIEALKLARQIALASRSHQDAKR 2710

Query: 789  EAAHPTDVSISKTALYSRIGTAEVEKPAGLLFQQPDLDSALQIARAEIITKEREVSEWKD 848
            EAAHPTDVSISKTALYSRIGTAEVEKPAGLLFQQPDLDSALQIARAEIITKEREVSEWKD
Sbjct: 2711 EAAHPTDVSISKTALYSRIGTAEVEKPAGLLFQQPDLDSALQIARAEIITKEREVSEWKD 2770

Query: 849  KYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQALADLNSVEK 908
            KYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQALADLNSVEK
Sbjct: 2771 KYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQALADLNSVEK 2830

Query: 909  SLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANA 968
            SLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANA
Sbjct: 2831 SLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANA 2890

Query: 969  EIAQVRGKAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEELTKICDELIAKMGKS 1026
            EIAQVRGKAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEELTKICDELIAKMGKS
Sbjct: 2891 EIAQVRGKAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEELTKICDELIAKMGKS 2948



 Score = 36.6 bits (83), Expect = 0.12
 Identities = 61/264 (23%), Positives = 87/264 (32%), Gaps = 45/264 (17%)

Query: 4    SQSLQPAPASDLNLEASEAMSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQP 63
            +Q   P P   +  +    M     +  +TPE      A P   P  P  IP  +     
Sbjct: 2278 NQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAK----- 2332

Query: 64   PPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNI-E 122
                   G+ T    D  + D    +PF   S        ++ P     +YN D D   E
Sbjct: 2333 -------GTYTF---DIDKWDDPNFNPFSSTSKM------QESPKLPQQSYNFDPDTCDE 2376

Query: 123  LVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPE 182
             VD F+T                     T S P SKS  S  +   A + +G    G  +
Sbjct: 2377 SVDPFKT------------------SSKTPSSP-SKSPASFEIPASAMEANGVDGDGLNK 2417

Query: 183  AVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPV-KETQQEPDEESLV 241
                      T +     + KR+    PPS  +  T     ETPPV        DEE L 
Sbjct: 2418 PAKKKKTPLKTDTFRVKKSPKRSPLSDPPS--QDPTPAATPETPPVISAVVHATDEEKLA 2475

Query: 242  PSGENLASET-KTESAKTEGPSPA 264
             + +     T   E+ K + P P+
Sbjct: 2476 VTNQKWTCMTVDLEADKQDYPQPS 2499



 Score = 35.8 bits (81), Expect = 0.21
 Identities = 131/593 (22%), Positives = 195/593 (32%), Gaps = 90/593 (15%)

Query: 19  ASEAMSSDSEEAFETPESTTPVKAPPAP--------PPPPPEVIPEPEVSTQP----PPE 66
           ASE+ S+  +    +PE T P K P           P PPP    E   S+ P    PPE
Sbjct: 61  ASES-SASLDPCLVSPEVTEPRKDPQGARGPEGSLLPSPPPSQEREHPSSSMPFAECPPE 119

Query: 67  EPGCGSETVPVP-DGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVD 125
             GC +     P DGP++ S    P        +A F  ++   SS  Y    +   +  
Sbjct: 120 --GCLASPAAAPEDGPQTQSPRREPAPNAPGDIAAAFPAERD--SSTPYQ---EIAAVPS 172

Query: 126 TFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEA-- 183
             +  +P+    K+     +   +S    P+      ++      D  G   S   EA  
Sbjct: 173 AGRERQPKEEGQKSSFSFSSGIDQSPGMSPVPLREPMKAPLCGEGDQPGGFESQEKEAAG 232

Query: 184 -------------VALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKE 230
                        V + P+A +       S+    K P  P     Q    P      +E
Sbjct: 233 GFPPAESRQGVASVQVTPEAPAAAQQGTESSAVLEKSPLKPMAPIPQ---DPAPRASDRE 289

Query: 231 T-QQEPDEESLVPSGENLAS---ETKTESAKTEGPSPALLEETPLEP--AVGPKAACPLD 284
             Q E   + L    E L +         A  E    A  +E+  +P  A  P A  P  
Sbjct: 290 RGQGEAPPQYLTDDLEFLRACHLPRSNSGAAPEAEVNAASQESCQQPVGAYLPHAELPWG 349

Query: 285 SESAEGVVPPASGGGR-------VQNSPPVG-RKTLP---------------LTTAPEAG 321
             S   +VP A G G+       VQ  P  G R T P               L  +PE  
Sbjct: 350 LPS-PALVPEAGGSGKEALDTIDVQGHPQTGMRGTKPNQVVCVAAGGQPEGGLPVSPEPS 408

Query: 322 EVTPSDSGGQEDSPAKGLSVRLEFDYSE-DKSSWDNQQENPPPTKKIGKKPVAKMPLRRP 380
            +TP++      S A   + ++     E   SS ++  +   P      K V    L   
Sbjct: 409 LLTPTEEAHPASSLASFPAAQIPIAVEEPGSSSRESVSKAGMPVSADAAKEVVDAGL--V 466

Query: 381 KMKKTPEKLDNTPASPPRSPAE-PNDIPIAKGTY-----TFDIDKWDDPNFNPFSSTSKM 434
            +++    L +    P   P E P   P  +G +     + ++     P   P   + ++
Sbjct: 467 GLERQVSDLGSKGEHPEGDPGEVPAPSPQERGEHLNTEQSHEVQPGVPPPPLPKEQSHEV 526

Query: 435 QES------PKLPQQSYNFDPDTCD-ESVDPFKTSSKTPSSPSKSPASFEIPASAMEANG 487
           Q        PK P +S    P   D   V    TS       S+SP   + P    EA  
Sbjct: 527 QPGAPPPPLPKAPSESARGPPGPTDGAKVHEDSTSPAVAKEGSRSPG--DSPGGKEEAPE 584

Query: 488 V--DGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPP 538
               GD  N   +  +         V K     P SD  S+D  P++    PP
Sbjct: 585 PPDGGDPGNLQGEDSQAFSSKRDPEVGKDELSKPSSDAESRD-HPSSHSAQPP 636


>gi|45827755 transforming, acidic coiled-coil containing protein 2
            isoform b [Homo sapiens]
          Length = 1094

 Score = 1986 bits (5146), Expect = 0.0
 Identities = 1003/1003 (100%), Positives = 1003/1003 (100%)

Query: 24   SSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRS 83
            SSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRS
Sbjct: 92   SSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRS 151

Query: 84   DSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGK 143
            DSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGK
Sbjct: 152  DSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGK 211

Query: 144  VNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLK 203
            VNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLK
Sbjct: 212  VNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLK 271

Query: 204  RTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSP 263
            RTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSP
Sbjct: 272  RTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSP 331

Query: 264  ALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEV 323
            ALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEV
Sbjct: 332  ALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEV 391

Query: 324  TPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMK 383
            TPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMK
Sbjct: 392  TPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMK 451

Query: 384  KTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQ 443
            KTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQ
Sbjct: 452  KTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQ 511

Query: 444  SYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTP 503
            SYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTP
Sbjct: 512  SYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTP 571

Query: 504  LKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMT 563
            LKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMT
Sbjct: 572  LKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMT 631

Query: 564  VDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQ 623
            VDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQ
Sbjct: 632  VDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQ 691

Query: 624  ALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHPVPRGLAPNQES 683
            ALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHPVPRGLAPNQES
Sbjct: 692  ALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHPVPRGLAPNQES 751

Query: 684  HLQVPEKSSQKELEAMGLGTPSEAIEITAPEGSFASADALLSRLAHPVSLCGALDYLEPD 743
            HLQVPEKSSQKELEAMGLGTPSEAIEITAPEGSFASADALLSRLAHPVSLCGALDYLEPD
Sbjct: 752  HLQVPEKSSQKELEAMGLGTPSEAIEITAPEGSFASADALLSRLAHPVSLCGALDYLEPD 811

Query: 744  LAEKNPPLFAQKLQEELEFAIMRIEALKLARQIALASRSHQDAKREAAHPTDVSISKTAL 803
            LAEKNPPLFAQKLQEELEFAIMRIEALKLARQIALASRSHQDAKREAAHPTDVSISKTAL
Sbjct: 812  LAEKNPPLFAQKLQEELEFAIMRIEALKLARQIALASRSHQDAKREAAHPTDVSISKTAL 871

Query: 804  YSRIGTAEVEKPAGLLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKI 863
            YSRIGTAEVEKPAGLLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKI
Sbjct: 872  YSRIGTAEVEKPAGLLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKI 931

Query: 864  VAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFRRYEKMKEV 923
            VAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFRRYEKMKEV
Sbjct: 932  VAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFRRYEKMKEV 991

Query: 924  LEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQEQAA 983
            LEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQEQAA
Sbjct: 992  LEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQEQAA 1051

Query: 984  HQASLRKEQLRVDALERTLEQKNKEIEELTKICDELIAKMGKS 1026
            HQASLRKEQLRVDALERTLEQKNKEIEELTKICDELIAKMGKS
Sbjct: 1052 HQASLRKEQLRVDALERTLEQKNKEIEELTKICDELIAKMGKS 1094



 Score = 36.6 bits (83), Expect = 0.12
 Identities = 61/264 (23%), Positives = 87/264 (32%), Gaps = 45/264 (17%)

Query: 4   SQSLQPAPASDLNLEASEAMSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQP 63
           +Q   P P   +  +    M     +  +TPE      A P   P  P  IP  +     
Sbjct: 424 NQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAK----- 478

Query: 64  PPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNI-E 122
                  G+ T    D  + D    +PF   S        ++ P     +YN D D   E
Sbjct: 479 -------GTYTF---DIDKWDDPNFNPFSSTSKM------QESPKLPQQSYNFDPDTCDE 522

Query: 123 LVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPE 182
            VD F+T                     T S P SKS  S  +   A + +G    G  +
Sbjct: 523 SVDPFKT------------------SSKTPSSP-SKSPASFEIPASAMEANGVDGDGLNK 563

Query: 183 AVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPV-KETQQEPDEESLV 241
                     T +     + KR+    PPS  +  T     ETPPV        DEE L 
Sbjct: 564 PAKKKKTPLKTDTFRVKKSPKRSPLSDPPS--QDPTPAATPETPPVISAVVHATDEEKLA 621

Query: 242 PSGENLASET-KTESAKTEGPSPA 264
            + +     T   E+ K + P P+
Sbjct: 622 VTNQKWTCMTVDLEADKQDYPQPS 645


>gi|45827753 transforming, acidic coiled-coil containing protein 2
            isoform c [Homo sapiens]
          Length = 996

 Score = 1960 bits (5077), Expect = 0.0
 Identities = 996/1026 (97%), Positives = 996/1026 (97%), Gaps = 30/1026 (2%)

Query: 1    MGGSQSLQPAPASDLNLEASEAMSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVS 60
            MGGSQSLQPAPASDLNLEASEAMSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVS
Sbjct: 1    MGGSQSLQPAPASDLNLEASEAMSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVS 60

Query: 61   TQPPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDN 120
            TQPPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDN
Sbjct: 61   TQPPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDN 120

Query: 121  IELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGN 180
            IELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGN
Sbjct: 121  IELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGN 180

Query: 181  PEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESL 240
            PEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESL
Sbjct: 181  PEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESL 240

Query: 241  VPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGR 300
            VPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGR
Sbjct: 241  VPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGR 300

Query: 301  VQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQEN 360
            VQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQEN
Sbjct: 301  VQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQEN 360

Query: 361  PPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKW 420
            PPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKW
Sbjct: 361  PPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKW 420

Query: 421  DDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPA 480
            DDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPA
Sbjct: 421  DDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPA 480

Query: 481  SAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVI 540
            SAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVI
Sbjct: 481  SAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVI 540

Query: 541  SAVVHATDEEKLAVTNQKWTCMTVDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNS 600
            SAVVHATDEEKLAVTNQKWTCMTVDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNS
Sbjct: 541  SAVVHATDEEKLAVTNQKWTCMTVDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNS 600

Query: 601  YEIEYMEKIGSSLPQDDDAPKKQALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEETE 660
            YEIEYMEKIGSSLPQDDDAPKKQALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEETE
Sbjct: 601  YEIEYMEKIGSSLPQDDDAPKKQALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEETE 660

Query: 661  ALVNTAAKNQHPVPRGLAPNQESHLQVPEKSSQKELEAMGLGTPSEAIEITAPEGSFASA 720
            ALVNTAAKNQHPVPRGLAPNQESHLQVPEKSSQKELEAMGLGTPSEAIEITAPEGSFASA
Sbjct: 661  ALVNTAAKNQHPVPRGLAPNQESHLQVPEKSSQKELEAMGLGTPSEAIEITAPEGSFASA 720

Query: 721  DALLSRLAHPVSLCGALDYLEPDLAEKNPPLFAQKLQEELEFAIMRIEALKLARQIALAS 780
            DALLSRLAHPVSLCGALDYLEPDLAEKNPPLFAQKLQ                       
Sbjct: 721  DALLSRLAHPVSLCGALDYLEPDLAEKNPPLFAQKLQ----------------------- 757

Query: 781  RSHQDAKREAAHPTDVSISKTALYSRIGTAEVEKPAGLLFQQPDLDSALQIARAEIITKE 840
                   REAAHPTDVSISKTALYSRIGTAEVEKPAGLLFQQPDLDSALQIARAEIITKE
Sbjct: 758  -------REAAHPTDVSISKTALYSRIGTAEVEKPAGLLFQQPDLDSALQIARAEIITKE 810

Query: 841  REVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQAL 900
            REVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQAL
Sbjct: 811  REVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQAL 870

Query: 901  ADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAE 960
            ADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAE
Sbjct: 871  ADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAE 930

Query: 961  EKLDRANAEIAQVRGKAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEELTKICDELI 1020
            EKLDRANAEIAQVRGKAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEELTKICDELI
Sbjct: 931  EKLDRANAEIAQVRGKAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEELTKICDELI 990

Query: 1021 AKMGKS 1026
            AKMGKS
Sbjct: 991  AKMGKS 996


>gi|170763517 transforming, acidic coiled-coil containing protein 1
            isoform 1 [Homo sapiens]
          Length = 805

 Score =  306 bits (785), Expect = 5e-83
 Identities = 279/891 (31%), Positives = 410/891 (46%), Gaps = 146/891 (16%)

Query: 169  ASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPT---ET 225
            A + +     G+PE      +  S   SS S     T +   P     + +  P+     
Sbjct: 27   AGEDEAGGPEGDPEEEDSQAETKSLSFSSDSEGNFETPEAETPIRSPFKESCDPSLGLAG 86

Query: 226  PPVKETQ-QEPDEESLVPSGENLASETKTESAKTEGPSPAL-------LEETPLEPAVGP 277
            P  K  + QE DE+ +    E  +S+T ++ ++ E P  A+         E P       
Sbjct: 87   PGAKSQESQEADEQLVAEVVEKCSSKTCSKPSENEVPQQAIDSHSVKNFREEPEHDFSKI 146

Query: 278  KAACPLDSESAEGVVPPASGGGRVQNS--PPVGRKTLPLTTAPEAGEVTPSDSGGQEDSP 335
                P   E+ +     A  G +  +     V  K LP +         P D+   E   
Sbjct: 147  SIVRPFSIETKDSTDISAVLGTKAAHGCVTAVSGKALPSS---------PPDALQDEAMT 197

Query: 336  AKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPAS 395
               + V LE     D  + ++  E  P  +   +KP   +PLR+   K    +  +T A+
Sbjct: 198  EGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKP-KPVPLRK---KAIGGEFSDTNAA 253

Query: 396  PPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQSYNFDPDTCDE 454
               +P       + K +Y F  ++ D+ N +P    ++ Q+SP  L +       DT D 
Sbjct: 254  VEGTP-------LPKASYHFSPEELDE-NTSPLLGDARFQKSPPDLKETPGTLSSDTNDS 305

Query: 455  SVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKS 514
             V+      ++ SSP K    F      +EA       L +      TP K     + KS
Sbjct: 306  GVE---LGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTP-KIQKDGISKS 361

Query: 515  P----------KRSPLSDPPSQ-DPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMT 563
                       +  PLS   S+ DP+   +P   P  S   H+  +    ++++      
Sbjct: 362  AGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGS---HSVLQNSPPLSSEGSYHFD 418

Query: 564  VDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQ 623
             D   +  D  +P+   T +  + F SPT                 G+ + +  ++PKK 
Sbjct: 419  PDNFDESMDPFKPT---TTLTSSDFCSPT-----------------GNHVNEILESPKKA 458

Query: 624  ALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHPVPRGLAP--NQ 681
               L+                    + C     E     ++  ++++  V   ++   N+
Sbjct: 459  KSRLI-------------------TSGCKVKKHETQSLALDACSRDEGAVISQISDISNR 499

Query: 682  ESHLQVPEKSS-----QKELEAMGLGTPSEAIEITAPEGSFASADALLSRLAHPVSLCGA 736
            + H    EK +     QK   A   G P E +E       F  ++  +S + H      A
Sbjct: 500  DGHATDEEKLASTSCGQKSAGAEVKGEPEEDLEY------FECSNVPVSTINH------A 547

Query: 737  LDYLEPDLAEKNPPLFAQKLQEELEFAIMRIEALKLARQIALASRSHQDAKREAAHPTDV 796
                E  + ++      QK++E+    +  +E+                    +A    V
Sbjct: 548  FSSSEAGIEKET----CQKMEEDGSTVLGLLES--------------------SAEKAPV 583

Query: 797  SISKTALYSRIGTAEVEKPA-GLLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRR 855
            S+S             E P  G+   + D  + L + R EIITKE E +EWK KYEE+R+
Sbjct: 584  SVSCGG----------ESPLDGICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQ 633

Query: 856  EVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFR 915
            EV+EMRKIVAEYEKTIAQMIEDEQR    S ++ QQL +EKEQALADLNSVE+SL+DLFR
Sbjct: 634  EVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFR 693

Query: 916  RYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRG 975
            RYE +K VLEGF+KNEE LK+CAQ+YL+RVK+EEQRYQALK+HAEEKLD+AN EIAQVR 
Sbjct: 694  RYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRT 753

Query: 976  KAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEELTKICDELIAKMGKS 1026
            KA+ E AA  A LRKEQ++V++LER L+QKN+EIEELTKICDELIAK+GK+
Sbjct: 754  KAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDELIAKLGKT 804



 Score =  122 bits (306), Expect = 2e-27
 Identities = 166/639 (25%), Positives = 261/639 (40%), Gaps = 120/639 (18%)

Query: 20  SEAMSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEE---------PGC 70
           S + SSDSE  FETPE+ TP+++P      P   +  P   +Q   E            C
Sbjct: 50  SLSFSSDSEGNFETPEAETPIRSPFKESCDPSLGLAGPGAKSQESQEADEQLVAEVVEKC 109

Query: 71  GSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTL 130
            S+T   P        E       SHS     +E +          DF  I +V  F   
Sbjct: 110 SSKTCSKP-----SENEVPQQAIDSHSVKNFREEPEH---------DFSKISIVRPFSI- 154

Query: 131 EPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSL--SLQASDFDGASSSGNPEAVALAP 188
                D+ +    + T+        +S   L  S   +LQ       S     EA A A 
Sbjct: 155 --ETKDSTDISAVLGTKAAHGCVTAVSGKALPSSPPDALQDEAMTEGSMGVTLEASAEAD 212

Query: 189 -DAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENL 247
             A ++      S   + +KP+P  L+KK                              +
Sbjct: 213 LKAGNSCPELVPSRRSKLRKPKPVPLRKKA-----------------------------I 243

Query: 248 ASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPV 307
             E    +A  EG        TPL     PKA+     E  +    P  G  R Q SPP 
Sbjct: 244 GGEFSDTNAAVEG--------TPL-----PKASYHFSPEELDENTSPLLGDARFQKSPPD 290

Query: 308 GRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKI 367
            ++T P T + +      +DSG +    ++   ++LEFD++ED  + + ++  P   +K+
Sbjct: 291 LKET-PGTLSSDT-----NDSGVELGEESRSSPLKLEFDFTEDTGNIEARKALP---RKL 341

Query: 368 GKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEP--NDIPIAKGTYTFDIDKWDDPNF 425
           G+K  + +    PK++K       + ++    P +P   D P+++ +   D  +W+ P+F
Sbjct: 342 GRKLGSTL---TPKIQKD----GISKSAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSF 394

Query: 426 NPFSSTSKMQESPKLPQQ-SYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAME 484
           NPF S S +Q SP L  + SY+FDPD  DES+DPFK ++   SS   SP    +      
Sbjct: 395 NPFGSHSVLQNSPPLSSEGSYHFDPDNFDESMDPFKPTTTLTSSDFCSPTGNHV------ 448

Query: 485 ANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVV 544
                 + L  P KK K+ L T   +VKK   +S   D  S+D   A   +   + +   
Sbjct: 449 -----NEILESP-KKAKSRLITSGCKVKKHETQSLALDACSRD-EGAVISQISDISNRDG 501

Query: 545 HATDEEKLAVTN--QKWTCMTVDLEADKQ-DYPQPSDLSTFVNETKFSSPTEELDYRNSY 601
           HATDEEKLA T+  QK     V  E ++  +Y + S++        FSS    ++     
Sbjct: 502 HATDEEKLASTSCGQKSAGAEVKGEPEEDLEYFECSNVPVSTINHAFSSSEAGIEKET-- 559

Query: 602 EIEYMEKIGSSLPQDDDAPKKQALYLMFDTSQESPVKSS 640
             + ME+ GS++           L L+  +++++PV  S
Sbjct: 560 -CQKMEEDGSTV-----------LGLLESSAEKAPVSVS 586


>gi|226246618 transforming, acidic coiled-coil containing protein 1
            isoform 3 [Homo sapiens]
          Length = 610

 Score =  300 bits (769), Expect = 4e-81
 Identities = 237/676 (35%), Positives = 336/676 (49%), Gaps = 115/676 (17%)

Query: 371  PVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSS 430
            P  +  LR+PK     +K      S   +  E   +P  K +Y F  ++ D+ N +P   
Sbjct: 29   PSRRSKLRKPKPVPLRKKAIGGEFSDTNAAVEGTPLP--KASYHFSPEELDE-NTSPLLG 85

Query: 431  TSKMQESPK-LPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVD 489
             ++ Q+SP  L +       DT D  V+      ++ SSP K    F      +EA    
Sbjct: 86   DARFQKSPPDLKETPGTLSSDTNDSGVE---LGEESRSSPLKLEFDFTEDTGNIEARKAL 142

Query: 490  GDGLNKPAKKKKTPLKTDTFRVKKSP----------KRSPLSDPPSQ-DPTPAATPETPP 538
               L +      TP K     + KS           +  PLS   S+ DP+   +P   P
Sbjct: 143  PRKLGRKLGSTLTP-KIQKDGISKSAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNP 201

Query: 539  VISAVVHATDEEKLAVTNQKWTCMTVDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYR 598
              S   H+  +    ++++       D   +  D  +P+   T +  + F SPT      
Sbjct: 202  FGS---HSVLQNSPPLSSEGSYHFDPDNFDESMDPFKPT---TTLTSSDFCSPT------ 249

Query: 599  NSYEIEYMEKIGSSLPQDDDAPKKQALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEE 658
                       G+ + +  ++PKK    L+                    + C     E 
Sbjct: 250  -----------GNHVNEILESPKKAKSRLI-------------------TSGCKVKKHET 279

Query: 659  TEALVNTAAKNQHPVPRGLAP--NQESHLQVPEKSS-----QKELEAMGLGTPSEAIEIT 711
                ++  ++++  V   ++   N++ H    EK +     QK   A   G P E +E  
Sbjct: 280  QSLALDACSRDEGAVISQISDISNRDGHATDEEKLASTSCGQKSAGAEVKGEPEEDLEY- 338

Query: 712  APEGSFASADALLSRLAHPVSLCGALDYLEPDLAEKNPPLFAQKLQEELEFAIMRIEALK 771
                 F  ++  +S + H      A    E  + ++      QK++E+    +  +E+  
Sbjct: 339  -----FECSNVPVSTINH------AFSSSEAGIEKET----CQKMEEDGSTVLGLLES-- 381

Query: 772  LARQIALASRSHQDAKREAAHPTDVSISKTALYSRIGTAEVEKPA-GLLFQQPDLDSALQ 830
                              +A    VS+S             E P  G+   + D  + L 
Sbjct: 382  ------------------SAEKAPVSVSCGG----------ESPLDGICLSESDKTAVLT 413

Query: 831  IARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQ 890
            + R EIITKE E +EWK KYEE+R+EV+EMRKIVAEYEKTIAQMIEDEQR    S ++ Q
Sbjct: 414  LIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQ 473

Query: 891  QLVLEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQ 950
            QL +EKEQALADLNSVE+SL+DLFRRYE +K VLEGF+KNEE LK+CAQ+YL+RVK+EEQ
Sbjct: 474  QLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQ 533

Query: 951  RYQALKVHAEEKLDRANAEIAQVRGKAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIE 1010
            RYQALK+HAEEKLD+AN EIAQVR KA+ E AA  A LRKEQ++V++LER L+QKN+EIE
Sbjct: 534  RYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIE 593

Query: 1011 ELTKICDELIAKMGKS 1026
            ELTKICDELIAK+GK+
Sbjct: 594  ELTKICDELIAKLGKT 609



 Score =  112 bits (279), Expect = 2e-24
 Identities = 112/383 (29%), Positives = 183/383 (47%), Gaps = 54/383 (14%)

Query: 264 ALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEV 323
           A +E TPL     PKA+     E  +    P  G  R Q SPP  ++T P T + +    
Sbjct: 57  AAVEGTPL-----PKASYHFSPEELDENTSPLLGDARFQKSPPDLKET-PGTLSSDT--- 107

Query: 324 TPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMK 383
             +DSG +    ++   ++LEFD++ED  + + ++  P   +K+G+K  + +    PK++
Sbjct: 108 --NDSGVELGEESRSSPLKLEFDFTEDTGNIEARKALP---RKLGRKLGSTLT---PKIQ 159

Query: 384 KTPEKLDNTPASPPRSPAEP--NDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLP 441
           K       + ++    P +P   D P+++ +   D  +W+ P+FNPF S S +Q SP L 
Sbjct: 160 KD----GISKSAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLS 215

Query: 442 QQ-SYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKK 500
            + SY+FDPD  DES+DPFK ++   SS   SP    +            + L  P KK 
Sbjct: 216 SEGSYHFDPDNFDESMDPFKPTTTLTSSDFCSPTGNHV-----------NEILESP-KKA 263

Query: 501 KTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTN--QK 558
           K+ L T   +VKK   +S   D  S+D   A   +   + +   HATDEEKLA T+  QK
Sbjct: 264 KSRLITSGCKVKKHETQSLALDACSRD-EGAVISQISDISNRDGHATDEEKLASTSCGQK 322

Query: 559 WTCMTVDLEADKQ-DYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDD 617
                V  E ++  +Y + S++        FSS    ++       + ME+ GS++    
Sbjct: 323 SAGAEVKGEPEEDLEYFECSNVPVSTINHAFSSSEAGIEKET---CQKMEEDGSTV---- 375

Query: 618 DAPKKQALYLMFDTSQESPVKSS 640
                  L L+  +++++PV  S
Sbjct: 376 -------LGLLESSAEKAPVSVS 391



 Score = 32.3 bits (72), Expect = 2.4
 Identities = 34/119 (28%), Positives = 53/119 (44%), Gaps = 11/119 (9%)

Query: 21  EAMSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPE---PEVSTQPPPEEPGCGSETVPV 77
           E+ SS  +  F+  E T  ++A  A P      +     P++      +  G    T PV
Sbjct: 117 ESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGISKSAGLEQPTDPV 176

Query: 78  P-DGPRSD-SVEGSPFRPPSHSFS-----AVFDEDKPIASSGTYNLDFDNI-ELVDTFQ 128
             DGP S  S +  P +  S SF+     +V     P++S G+Y+ D DN  E +D F+
Sbjct: 177 ARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSYHFDPDNFDESMDPFK 235


>gi|170763519 transforming, acidic coiled-coil containing protein 1
            isoform 2 [Homo sapiens]
          Length = 395

 Score =  298 bits (762), Expect = 2e-80
 Identities = 149/210 (70%), Positives = 179/210 (85%)

Query: 817  GLLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIE 876
            G+   + D  + L + R EIITKE E +EWK KYEE+R+EV+EMRKIVAEYEKTIAQMIE
Sbjct: 185  GICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIE 244

Query: 877  DEQREKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKR 936
            DEQR    S ++ QQL +EKEQALADLNSVE+SL+DLFRRYE +K VLEGF+KNEE LK+
Sbjct: 245  DEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKK 304

Query: 937  CAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQEQAAHQASLRKEQLRVD 996
            CAQ+YL+RVK+EEQRYQALK+HAEEKLD+AN EIAQVR KA+ E AA  A LRKEQ++V+
Sbjct: 305  CAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVE 364

Query: 997  ALERTLEQKNKEIEELTKICDELIAKMGKS 1026
            +LER L+QKN+EIEELTKICDELIAK+GK+
Sbjct: 365  SLERALQQKNQEIEELTKICDELIAKLGKT 394


>gi|5454102 transforming, acidic coiled-coil containing protein 3
            [Homo sapiens]
          Length = 838

 Score =  211 bits (537), Expect = 3e-54
 Identities = 107/208 (51%), Positives = 151/208 (72%), Gaps = 7/208 (3%)

Query: 818  LLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIED 877
            L + Q DLD+ ++         + E  E + + EE   + +E+ KI+  +E+ + Q +E+
Sbjct: 637  LQYSQKDLDAVVKAT-------QEENRELRSRCEELHGKNLELGKIMDRFEEVVYQAMEE 689

Query: 878  EQREKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRC 937
             Q++K +S   +Q+++ EK+Q   DLNS+EKS +DLF+R+EK KEV+EG+RKNEE LK+C
Sbjct: 690  VQKQKELSKAEIQKVLKEKDQLTTDLNSMEKSFSDLFKRFEKQKEVIEGYRKNEESLKKC 749

Query: 938  AQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQEQAAHQASLRKEQLRVDA 997
             ++YL+R+ +E QRYQALK HAEEKL  AN EIAQVR KAQ E  A QASLRKEQ+R+ +
Sbjct: 750  VEDYLARITQEGQRYQALKAHAEEKLQLANEEIAQVRSKAQAEALALQASLRKEQMRIQS 809

Query: 998  LERTLEQKNKEIEELTKICDELIAKMGK 1025
            LE+T+EQK KE EELT+ICD+LI+KM K
Sbjct: 810  LEKTVEQKTKENEELTRICDDLISKMEK 837



 Score =  102 bits (254), Expect = 2e-21
 Identities = 192/868 (22%), Positives = 329/868 (37%), Gaps = 177/868 (20%)

Query: 132 PRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAY 191
           P  +  +NQ+       K+T  +          L   AS   G+ SS      ALA    
Sbjct: 95  PVWTQKENQQLIKEVDAKTTHGILQKPVEADTDLLGDASPAFGSGSSSESGPGALADLDC 154

Query: 192 STGSSSASSTLKRTKKPRPPSLKKKQTTKKPTET-------PPVKETQQEP-----DEES 239
           S+ S S  S+  +   P   S   +Q  ++   +        P  ET ++P       ++
Sbjct: 155 SSSSQSPGSSENQMVSPGKVSGSPEQAVEENLSSYSLDRRVTPASETLEDPCRTESQHKA 214

Query: 240 LVPSGENLASETKTESAKTEGP------SPALLEETPLEPAVGPKAAC---PLDSESAEG 290
             P G     + +T     E        +PA +  +P  P   PK AC   PL     E 
Sbjct: 215 ETPHGAEEECKAETPHGAEEECRHGGVCAPAAVATSP--PGAIPKEACGGAPLQGLPGEA 272

Query: 291 VVPPASGGGRVQNSPPVGRKTL-------PLTTAP-------EAGEVTPSD--SGGQEDS 334
           +  PA  G  V   P  G +TL       P +TAP        A  ++P +  + GQ  S
Sbjct: 273 LGCPAGVGTPV---PADGTQTLTCAHTSAPESTAPTNHLVAGRAMTLSPQEEVAAGQMAS 329

Query: 335 PAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRP--KMKKTPEKLDNT 392
            ++   V+LEFD S+  +S     +  PP +++G++   K PLR+   + +K P++++  
Sbjct: 330 SSRSGPVKLEFDVSDGATS-----KRAPPPRRLGERSGLKPPLRKAAVRQQKAPQEVEED 384

Query: 393 PASPPRSPA-EPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDT 451
                RS A E   +P ++G+Y  D DK DDPNF PF   +K                  
Sbjct: 385 DG---RSGAGEDPPMPASRGSYHLDWDKMDDPNFIPFGGDTK----------------SG 425

Query: 452 CDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRV 511
           C E+  P     ++P +    PA+ ++ A               PA ++  P        
Sbjct: 426 CSEAQPP-----ESPETRLGQPAAEQLHAG--------------PATEEPGPCL------ 460

Query: 512 KKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTVDLE-ADK 570
                        SQ    A+  +TP V  A    T E K    N   T +      ++ 
Sbjct: 461 -------------SQQLHSASAEDTPVVQLAAETPTAESKERALNSASTSLPTSCPGSEP 507

Query: 571 QDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQALYLMFD 630
               Q    +  + E  F  P E L      E++Y+E+ G+S    + A +KQ+LYL FD
Sbjct: 508 VPTHQQGQPALELKEESFRDPAEVLG--TGAEVDYLEQFGTS-SFKESALRKQSLYLKFD 564

Query: 631 -TSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHPVPRGLAPNQESHLQVPE 689
              ++SP +  PV    S                +    N+ P  R            P 
Sbjct: 565 PLLRDSPGRPVPVATETS----------------SMHGANETPSGR------------PR 596

Query: 690 KSSQKELEAMG---LGTPSEAIEITAPEGSFASADALLSRLAHPVSLCGALDYLEPDLAE 746
           ++   E + +G   +  P     + AP G              P+S    +D L+   ++
Sbjct: 597 EAKLVEFDFLGALDIPVPGPPPGVPAPGGP-------------PLSTGPIVDLLQ--YSQ 641

Query: 747 KNPPLFAQKLQEELEFAIMRIEALKLARQIALASRSHQDAKREAAHPTDVSISKTALYSR 806
           K+     +  QEE      R E L   + + L      D   E  +     + K      
Sbjct: 642 KDLDAVVKATQEENRELRSRCEELH-GKNLELG--KIMDRFEEVVYQAMEEVQK---QKE 695

Query: 807 IGTAEVEKPAGLLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAE 866
           +  AE++K   +L ++  L + L           +   + K+  E  R+    ++K V +
Sbjct: 696 LSKAEIQK---VLKEKDQLTTDLNSMEKSFSDLFKRFEKQKEVIEGYRKNEESLKKCVED 752

Query: 867 YEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQ-------ALADLNSVEKSLADLFRRYEK 919
           Y   +A++ ++ QR +++     ++L L  E+       A A+  +++ SL     R + 
Sbjct: 753 Y---LARITQEGQRYQALKAHAEEKLQLANEEIAQVRSKAQAEALALQASLRKEQMRIQS 809

Query: 920 MKEVLEGFRKNEEVLKRCAQEYLSRVKK 947
           +++ +E   K  E L R   + +S+++K
Sbjct: 810 LEKTVEQKTKENEELTRICDDLISKMEK 837


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 80.1 bits (196), Expect = 1e-14
 Identities = 136/573 (23%), Positives = 189/573 (32%), Gaps = 65/573 (11%)

Query: 9    PAPASDLNLEASEAMSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEP 68
            P P +          ++ S +   TP + TP      P  P P+  P P   T P P+  
Sbjct: 963  PTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPK-- 1020

Query: 69   GCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQ 128
            G  + T P P G  S     +P  P     +    +  P   + T               
Sbjct: 1021 GSPAAT-PFPKG-ASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKG 1078

Query: 129  TLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAP 188
               P A+   + +G   T       +P + +  S    L      GA ++  P A   +P
Sbjct: 1079 APTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTT--PAATPPSP 1136

Query: 189  -DAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENL 247
                +T     + T      P P         K    TPP K     P      P G  L
Sbjct: 1137 KGGLATPPPKGAPTTPAATPPSP---------KGGLATPPPKGAPTTPAATPPSPKG-GL 1186

Query: 248  ASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPV 307
            A    T S K    +PA    TP  P  G     P  + +     PP+  GG    SP  
Sbjct: 1187 A----TPSPKGAPTTPA---ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPK- 1238

Query: 308  GRKTLPLTT--APEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPP--- 362
            G  T P  T  +P+ G  TP   G      A   S++        K + +     PP   
Sbjct: 1239 GAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPK 1298

Query: 363  -----------PTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKG 411
                       PT      P  K     P  K  P     TP SP  +P  P   P +KG
Sbjct: 1299 GGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKG 1358

Query: 412  TYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSK 471
              T    K + P   P ++T   +  P +   S    P       DP  + +  P SP K
Sbjct: 1359 GPTTPSSK-EGP--TPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDP-TSPAVIPLSPKK 1414

Query: 472  SPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKK-----SPKRSPLSDPPSQ 526
            +PA+            V  +G   P+K   TP       +KK     +PK  P +     
Sbjct: 1415 APAT-----------PVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKG 1463

Query: 527  DPT-PAAT---PETPPVISAVVHATDEEKLAVT 555
            DPT PA T   P+ PP    V  ++  +K   T
Sbjct: 1464 DPTLPAVTPPSPKEPPAPKQVATSSSPKKAPAT 1496



 Score = 74.3 bits (181), Expect = 5e-13
 Identities = 197/957 (20%), Positives = 317/957 (33%), Gaps = 141/957 (14%)

Query: 37   TTPVKAPPAPP----PPPPEVIPEPEVSTQPPPE----------EPGCGSETVPVPDGP- 81
            TTP   PP+P      PPP+  P    +T P P+           P   + T P P G  
Sbjct: 1150 TTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGL 1209

Query: 82   RSDSVEGSPFRP------PSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRAS 135
             + S +G+P  P      P    +    +  P   + T                  P A+
Sbjct: 1210 ATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAA 1269

Query: 136  DAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGS 195
               + +G + T        P  K   + ++    S   G ++S  P+     P A     
Sbjct: 1270 TPPSLKGGLAT--------PPHKGAPNPAVVTPPSPKGGPATSP-PKGAPTPPAATPPSP 1320

Query: 196  SSASSTLKRTKKPRPPSL---KKKQTTKKPTETPPVK------ETQQEPDEESLVPSGEN 246
              +  T      P PP++     K T   P  TP  K       +++ P   +  PS + 
Sbjct: 1321 KGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKG 1380

Query: 247  LASETKTESAKTEGPSPALLEETPLEPAV---GPKAACPLDSESAEGVVPPASGGGRVQN 303
                  T  +   GP+    +  P  PAV    PK A P    + EG   P+ G      
Sbjct: 1381 --GPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKA-PATPVTREGAATPSKGDLTPPA 1437

Query: 304  SPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPP 363
              PV  K  P T+AP+ G  TPS S G    PA                      + PP 
Sbjct: 1438 VTPVSLKKAPATSAPKGGPATPS-SKGDPTLPA----------------VTPPSPKEPPA 1480

Query: 364  TKKIG------KKPVAKMPLRRPKM----KKTPEKLDNTPASPPRSPAEPNDIPIAKGTY 413
             K++       K P    P+  P +      +P+++  TP+S  R P  P    ++K T 
Sbjct: 1481 PKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSS-RRDPIAPTATLLSKKTP 1539

Query: 414  TFDIDK------------------WDDPNFNPFSSTSKMQES-PKLPQQSYNFDPDTCDE 454
                 K                     P   P + +SK   S P +   +Y   P   + 
Sbjct: 1540 ATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKEL 1599

Query: 455  SVDPFKTS---SKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRV 511
             + P  TS    + P+ P+ +P S E   +     G        P+  K +P    +   
Sbjct: 1600 LIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTC 1659

Query: 512  K------KSPKRSPLSDPPS--QDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMT 563
            K      ++ K  P    P+  ++   A  PE+ P+I+A      + K +       C  
Sbjct: 1660 KMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPIC-- 1717

Query: 564  VDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQ 623
                      P PS  +         +P   L  +         K  S  P+   AP + 
Sbjct: 1718 ----------PDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPES 1767

Query: 624  ALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHPVPRGLAPNQES 683
                    +    V   P   S S  P    S     + V T    Q  +P       ES
Sbjct: 1768 KASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLES 1827

Query: 684  HLQVPEKSSQKEL------EAMGLGTPSEAIEITAPEGSFASADALLSRLAHPVSLCGAL 737
              +    + + EL      E +  G P +++ +  P    A           PV+     
Sbjct: 1828 PSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKG 1887

Query: 738  DYLEPDLAEKNPPLFAQ-KLQEELEFAIMRIEALKLARQIALASRSHQDAKREAAHPTDV 796
               E D  E  P L  Q   Q   + A +   A      ++ A +S  + K   A     
Sbjct: 1888 SGTESDSDESVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKAKQSRSEKKARKA----- 1942

Query: 797  SISKTALYSRIGTAEV--EKPAGLLF--QQPDLDSALQIARAEIITKEREVSEWKDKYEE 852
             +SK  L    G   V   K   +LF   +PD+  +   +   I+  E ++   +D  ++
Sbjct: 1943 -MSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKS-PASDTYIVFGEAKI---EDLSQQ 1997

Query: 853  SRREVMEMRKIVAE-----YEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQALADLN 904
            ++    E  K+  E      E T    +++E  E+ V    V+   +E   + A+++
Sbjct: 1998 AQLAAAEKFKVQGEAVSNIQENTQTPTVQEESEEEEVDETGVEVKDIELVMSQANVS 2054



 Score = 71.6 bits (174), Expect = 3e-12
 Identities = 142/663 (21%), Positives = 229/663 (34%), Gaps = 86/663 (12%)

Query: 33   TPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPE-EPGCGSETVPVPDGPRSDSVEGSPF 91
            TP + TP     +P  PPP+  P P   T P P+  P   + T     GP + S +  P 
Sbjct: 1311 TPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPT 1370

Query: 92   RP---PSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAK--NQEGKVNT 146
             P   PSH          P       +   D          L P+ + A    +EG    
Sbjct: 1371 PPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTS--PAVIPLSPKKAPATPVTREGAATP 1428

Query: 147  RRKSTDSVPISKSTLSRSLSLQASDFDGA--SSSGNPEAVALAPDA-------YSTGSSS 197
             +       ++  +L ++ +  A     A  SS G+P   A+ P +           +SS
Sbjct: 1429 SKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSS 1488

Query: 198  ASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEP-----------------DEESL 240
            +      T  P             P E P    ++++P                  +E+L
Sbjct: 1489 SPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEAL 1548

Query: 241  VPSGENLASETKTESAKT--EGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGG 298
            +P    + S  KT +  T  E P+    +E    PAV P       S   E ++PPA   
Sbjct: 1549 IPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPK-ELLIPPAVTS 1607

Query: 299  GRVQNSPPVGRKTLPLTTAPEAGEVTPSDSG----------GQEDSPAKGLSVRLEFDYS 348
               + +P     T P   +PE G  TP+  G            +DSP    SV  +   +
Sbjct: 1608 PSPKEAPTPPAVTPP---SPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGAT 1664

Query: 349  EDKSSWD-NQQENPPPTKKIGKKPVAK-MPLRRPKMKKTPEKLDNTPASPPRSPAEPNDI 406
              ++S     ++ P   K++   P  +  P+     +K P+   ++  SPP  P +P+  
Sbjct: 1665 VPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICP-DPSAK 1723

Query: 407  PIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTP 466
              +KG               P S+ +    +P LP Q    D     +  D    S K P
Sbjct: 1724 NGSKG---------------PLSTVA---PAPLLPVQK---DSSKTAKGKDA-SHSPKGP 1761

Query: 467  SSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQ 526
             +P +S AS  + A+A E        L KP     +   +    +  +P   P   P  Q
Sbjct: 1762 LAPPESKASTPLTAAAFE------KVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQ 1815

Query: 527  --DPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTVDLEADKQDYPQPSDLSTFVN 584
                +P    E+P     +  A ++E L +   +     V  ++   + P P      V 
Sbjct: 1816 FLPSSPGLVLESPS--KPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVP 1873

Query: 585  ETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDD-DAPKKQALYLMFDTSQESPVKSSPVR 643
                  P  + +  +  E +  E +     QD   A  +QA         E PV  +   
Sbjct: 1874 TPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKAKQS 1933

Query: 644  MSE 646
             SE
Sbjct: 1934 RSE 1936



 Score = 58.2 bits (139), Expect = 4e-08
 Identities = 133/588 (22%), Positives = 189/588 (32%), Gaps = 102/588 (17%)

Query: 20   SEAMSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPP---PEEPGCGSETVP 76
            S  MSS      E       V AP AP  P  +V     +   PP   PE+      +V 
Sbjct: 464  SPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVL 523

Query: 77   VPDGPRSD------SVEGSPFRPPSHSFSAVFDED-KPIASSGTYNLDFDNIELVDTFQT 129
            V    + D      S+EG+PF P     +   D    P+  +   N              
Sbjct: 524  VKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIP 583

Query: 130  LEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSG---------- 179
            L P A+ AK   G+     K   S+       S +  ++   + G  S+G          
Sbjct: 584  LSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITP 643

Query: 180  ----------NPEAVA-LAPDAYSTGSSSASSTLKRTKK--PRPPSLKKKQTTKKP---- 222
                      +P  VA       ST +++AS  L+ T    P+   +K+   T  P    
Sbjct: 644  TVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPT 703

Query: 223  -TETPPVKETQQE-----------PDEESLVPSGENLASETKTESAKTEGPSPALLEETP 270
             +E  PV  + Q            P+    VPS     + T   + K +G S      + 
Sbjct: 704  ASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGIS----HTSA 759

Query: 271  LEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSP-PVGRKTLPLTTAP--EAGEVTPSD 327
            L P       CP +   A            + +SP P+G    P T  P  + G   P  
Sbjct: 760  LAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDT 819

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENP-------PPTKKIGKKPVAKMPLRRP 380
              G   SP   +         E+  S+   +++P       PP+ K    P A  PL  P
Sbjct: 820  PIGNLSSPVSPVEASF---LPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPL-SP 875

Query: 381  KMKKTPEKLDNTPA-----SPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQ 435
            K    P K   TP+      P   PA P                   P  +  SS+ K  
Sbjct: 876  KGVTLPPKETPTPSVVNLPFPKEGPATP--------------APKQAPALSMTSSSPKKA 921

Query: 436  ESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPAS-----FEIPASAMEANGVDG 490
             +   P +     P        P    + TP SP   PA+        P +A   +   G
Sbjct: 922  RATPAP-KGIPASPSPKGAPTPP----AATPPSPKGGPATPSPKWAPTPPAATPPSPKGG 976

Query: 491  DGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPT-PAATPETP 537
                 P      P  T       SPK  P +  P   PT PA TP +P
Sbjct: 977  PATPSPKGAPTPPAAT-----PPSPKGGPATPSPKGAPTPPAVTPPSP 1019



 Score = 57.8 bits (138), Expect = 5e-08
 Identities = 118/518 (22%), Positives = 148/518 (28%), Gaps = 60/518 (11%)

Query: 45   APPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDE 104
            A  P P  V   P+  T+ PP + G      P+ +     S   + F P  +S S    +
Sbjct: 791  ADSPSPLGVSVSPQ--TKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLP-ENSLSFQGSK 847

Query: 105  DKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRS 164
            D P  +                   L P+      +E    T   S  ++P  K   +  
Sbjct: 848  DSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKE----TPTPSVVNLPFPKEGPATP 903

Query: 165  LSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTE 224
               QA      SSS  P+     P      +S +           PPS K    T  P  
Sbjct: 904  APKQAPALSMTSSS--PKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKW 961

Query: 225  TP-PVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPL 283
             P P   T   P      PS +               P+P     TP  P  GP    P 
Sbjct: 962  APTPPAATPPSPKGGPATPSPKG-------------APTPPAA--TPPSPKGGPATPSPK 1006

Query: 284  DSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPE-----------------AGEVTPS 326
             + +   V PP+  G       P G  T P  T P                       PS
Sbjct: 1007 GAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPS 1066

Query: 327  DSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTP 386
              GG      KG            K           P       P  K  L  P  K  P
Sbjct: 1067 PKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAP 1126

Query: 387  EKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSK-MQESPKLPQQSY 445
                 TPA+ P SP      P  KG  T        P     +   K    +P     S 
Sbjct: 1127 ----TTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSP 1182

Query: 446  NFDPDTCDESVDPFKTSSKTPSSP-----SKSPASFEIPASAMEANGVDGDGLNKPAKKK 500
                 T      P  T + TP SP     + SP       +A   +   G     P    
Sbjct: 1183 KGGLATPSPKGAP-TTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAP 1241

Query: 501  KTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPP 538
             TP  T       SPK  P + PP   PTP A   TPP
Sbjct: 1242 TTPAAT-----PPSPKGGPATPPPKGAPTPPAA--TPP 1272



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 103/419 (24%), Positives = 143/419 (34%), Gaps = 97/419 (23%)

Query: 48  PPPPEVIPEPEVSTQPPPEEP--------GCGSETVPVPDGPR------SDSVEGSPFRP 93
           P   + +P+P+  T   P           G    T+P P  P       S + + SPF  
Sbjct: 10  PATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPS 69

Query: 94  PSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDS 153
           PS   S   +   P +SSGT  L         TF           N  G           
Sbjct: 70  PSTIASTPLEVPFPQSSSGT-ALPLGTAPEAPTF---------LPNLIGP---------- 109

Query: 154 VPISKSTLSRSLSLQASDFDGASSSGNPEA-VALAPDAYSTGSS--------------SA 198
            PIS + L+ +  + A    G  SS  P A VALAP +    S+              + 
Sbjct: 110 -PISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAE 168

Query: 199 SSTLKRTKKPRPPSLKKKQTTKKPTE-TPPVKETQQEPDEESLVP-----------SG-E 245
           S ++     P  PS  K    K P+E  P  K T   P   S VP           SG  
Sbjct: 169 SGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVA 228

Query: 246 NLASETKTESAKTEGP------------SPALLEETPLEPAVGPKAACPLDSESAEGVVP 293
           +L   T T +     P            SP       L+  V P AA  L ++S   V  
Sbjct: 229 SLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTS 288

Query: 294 PASGGGRVQNSPP-----VGRKTLPL-----TTAPEAGEVTPSDSGGQEDSPAKGLSVRL 343
                G   N+PP     +G    PL      +    G+  PS      D   K +SV  
Sbjct: 289 SQKTAG--PNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPS---ALSDPTVKTISV-- 341

Query: 344 EFDYSEDKSSWDNQQENPPP---TKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRS 399
             D+S   +S+ +Q+   PP     ++    VA  P+  P + K P  + +   SP  S
Sbjct: 342 --DHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGS 398



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 76/372 (20%), Positives = 133/372 (35%), Gaps = 47/372 (12%)

Query: 22   AMSSDSEEAFETPESTTPVKAPPAPPPPPPEVIP-EPEVSTQPPPEEPGCGSETVPVPDG 80
            A++S S +   TP + TP      P  P P+  P  P V+     + P   +        
Sbjct: 1604 AVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGA 1663

Query: 81   PRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQ 140
                + +G P +    +   V     P ++          I    T +  + + S A + 
Sbjct: 1664 TVPQASKGLPAKKGPTALKEVLVAPAPESTP---------IITAPTRKGPQTKKSSATSP 1714

Query: 141  EGKVNTRRKSTDSVPISKSTLSRSLSLQ---ASDFDGASSSGNPEAVALAPDAYSTGSSS 197
                +   K+    P+S    +  L +Q   +    G  +S +P+     P++ ++   +
Sbjct: 1715 PICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLT 1774

Query: 198  ASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAK 257
            A++  K   KP   S+           +PPV          +L P  + L S        
Sbjct: 1775 AAAFEKVLPKPESASV-------SAAPSPPVSLPLAPSPVPTLPPKQQFLPS-------- 1819

Query: 258  TEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVP--PASGGGRVQ----NSPPVGRKT 311
                SP L+ E+P +P        P D +    ++P  P SGG   Q    N P      
Sbjct: 1820 ----SPGLVLESPSKP------LAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAG 1869

Query: 312  LPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKP 371
            +P+ T      VT ++ G   +S +      LE    +D +    QQ       +I ++P
Sbjct: 1870 IPVPTPSAKQPVTKNNKGSGTESDSDESVPELE---EQDSTQATTQQAQLAAAAEIDEEP 1926

Query: 372  VAKMPLRRPKMK 383
            V+K    R + K
Sbjct: 1927 VSKAKQSRSEKK 1938


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 78.6 bits (192), Expect = 3e-14
 Identities = 153/698 (21%), Positives = 232/698 (33%), Gaps = 89/698 (12%)

Query: 11  PASDLNLEASEAMSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPE---PEVSTQPPP-- 65
           PA     E +   +  +    + P  TTP K  P  P  P    P+   P    +P P  
Sbjct: 278 PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTT 337

Query: 66  EEPGCGSETVPVPDGPRSDSVEGSPFRP----PSHSFSAVFDEDKPIASSGTYNLDFDNI 121
           +EP   +   P P  P+  +   +P  P    P         E  P              
Sbjct: 338 KEPAPTTPKEPAPTAPKKPA-PTTPKEPAPTTPKEPAPTTTKEPSPTTPK---------- 386

Query: 122 ELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNP 181
                    EP  +  K+      T ++   +   S  T  +  S   +     ++   P
Sbjct: 387 ---------EPAPTTTKSAP---TTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP 434

Query: 182 EAVALAPDAYSTGSSSASSTLKR-----TKKPRPPSLKK--KQTTKKPTETPPVKETQQE 234
                   A +T    A +T K      TKKP P + K+    T K+   T P K T   
Sbjct: 435 APTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 494

Query: 235 PDEESLVP-SGENLASETKTESAKT--EGPSPALLEETPLEPA-VGPKAACPLDSESAEG 290
           P  E L P + E  A  T  E A T  E P+P     TP EPA   PKAA P   +    
Sbjct: 495 P--EKLAPTTPEKPAPTTPEELAPTTPEEPTPT----TPEEPAPTTPKAAAPNTPKEPAP 548

Query: 291 VVP----PASGGGRVQNSPPVGRKTLPLTTAP----EAGEVTPSDSGGQEDSPAKGLSVR 342
             P    P +       +P     T P  TAP    E    TP     +E +P    + +
Sbjct: 549 TTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT---TTK 605

Query: 343 LEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAE 402
                + DK +    +   P T K       K P         P  L     + P+ PA 
Sbjct: 606 EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAP 665

Query: 403 PNDIP-IAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFK- 460
               P   KG  +   DK         + T+  + +P  P++     P+T   +      
Sbjct: 666 KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVST 725

Query: 461 -TSSKTPSSPSKSPASFEIPASAMEA-NGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRS 518
            T++K P++  KSP       SA      ++           KTP  T       +  ++
Sbjct: 726 PTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKT 785

Query: 519 PLSDPPSQDPTPAATPETPPVISAVVHATDEEKL-AVTNQKWTCMTVDLEADKQDYPQPS 577
              D  +   T  A P+     +     T E K+ A T Q  +  T D    K    + +
Sbjct: 786 TERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTT 845

Query: 578 DLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQALYLMFDTSQESPV 637
            L+  V  TK +  T E+          M K     P++   PK +A     ++   +P 
Sbjct: 846 TLAPKVTTTKKTITTTEI----------MNK-----PEETAKPKDRAT----NSKATTPK 886

Query: 638 KSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHPVPR 675
              P +  + PT     S ++ + +         P PR
Sbjct: 887 PQKPTKAPKKPT-----STKKPKTMPRVRKPKTTPTPR 919



 Score = 68.2 bits (165), Expect = 4e-11
 Identities = 126/605 (20%), Positives = 192/605 (31%), Gaps = 101/605 (16%)

Query: 109 ASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPIS-------KSTL 161
           A SG  N DF  +   DT  T          Q  KV+T  K T + PI+        S  
Sbjct: 88  AGSGLDNGDF-KVTTPDTSTT----------QHNKVSTSPKITTAKPINPRPSLPPNSDT 136

Query: 162 SRSLSL-----------QASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRP 210
           S+  SL           + +  +  +S+   E    A +  S   +SA      +K    
Sbjct: 137 SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK 196

Query: 211 PSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEETP 270
           P+ K + TTK P  T P + T   P E +     E   +  K+     + P+P   +  P
Sbjct: 197 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 256

Query: 271 LEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVT---PSD 327
                 PK   P  ++      P        +   P   K+ P TT  E    T   P+ 
Sbjct: 257 ----TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAP-TTPKEPAPTTPKKPAP 311

Query: 328 SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
           +  +E +P            +  K       + P PT K       K P      K  P 
Sbjct: 312 TTPKEPAP------------TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP- 358

Query: 388 KLDNTPASP-PRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYN 446
               TP  P P +P EP                       P ++      +PK P  +  
Sbjct: 359 ---TTPKEPAPTTPKEP----------------------APTTTKEPSPTTPKEPAPTTT 393

Query: 447 FDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKT 506
               T  +   P  T S   +    SP + + PA                    K P  T
Sbjct: 394 KSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPT 453

Query: 507 DTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTV-- 564
                  +  + P    P ++P P    ET P     +  T  EKLA T  +    T   
Sbjct: 454 TPKEPAPTTTKKPAPTTP-KEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPE 512

Query: 565 DLEADKQDYPQPSDLSTFVNET-KFSSPTEELDYRNSYEIEYMEKIGSSLPQD--DDAPK 621
           +L     + P P+        T K ++P               ++   + P++     PK
Sbjct: 513 ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTP------------KEPAPTTPKEPAPTTPK 560

Query: 622 KQALYLMFDTSQESPVKSSPVRMSE-------SPTPCSGSSFEETEALVNTAAKNQHPVP 674
           + A     +T+  +P  ++P  + E        P P   +     E    T  K     P
Sbjct: 561 EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP 620

Query: 675 RGLAP 679
           +G AP
Sbjct: 621 KGTAP 625



 Score = 57.0 bits (136), Expect = 9e-08
 Identities = 106/514 (20%), Positives = 169/514 (32%), Gaps = 67/514 (13%)

Query: 214 KKKQTTKKPTETPPVKETQQEPDEESLVPSGENLAS--ETKTESAKTEGPSPALLEETPL 271
           KK +T KKPT  PPV +     +  S + +G+   +  +T T        SP +    P 
Sbjct: 70  KKNRTKKKPTPKPPVVD-----EAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKP- 123

Query: 272 EPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQ 331
              + P+ + P +S++++            + S  V ++     T  E  E T ++    
Sbjct: 124 ---INPRPSLPPNSDTSK------------ETSLTVNKE-----TTVETKETTTTNKQTS 163

Query: 332 EDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPV--AKMPLRRPKMKKTPEKL 389
            D   K  S +      E +S      ++  PT K+  KP   A+   + P +    E  
Sbjct: 164 TDGKEKTTSAK------ETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPT 217

Query: 390 DNTPASP-PRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFD 448
             TP  P   +P EP    I     T        P     ++T     +PK P  +   +
Sbjct: 218 PTTPKEPASTTPKEPTPTTIKSAPTT--------PKEPAPTTTKSAPTTPKEPAPTTTKE 269

Query: 449 P-DTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTD 507
           P  T  +   P  T    P++   +P + + PA               P +   T  K  
Sbjct: 270 PAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAP----TTPKEPAPTTPKEP 325

Query: 508 TFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTVDLE 567
           T    K P       P +++P P    E  P        T  ++ A T  K    T   E
Sbjct: 326 TPTTPKEPA------PTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKE 379

Query: 568 AD--KQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQAL 625
                   P P+   +    TK  +PT       + +           P     P     
Sbjct: 380 PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP 439

Query: 626 YLMFDTSQESPVKSSPVRMSESPTPCSGSSFEET---EALVNTAAKNQHPVPRGLAPNQE 682
                T+ + P  ++P    + P P +      T   E    T  +     P+ L P   
Sbjct: 440 KKPAPTTPKEPAPTTP----KEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTP 495

Query: 683 SHL--QVPEKSSQKELEAMGLGTPSEAIEITAPE 714
             L    PEK +    E +   TP E    T  E
Sbjct: 496 EKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE 529



 Score = 53.9 bits (128), Expect = 8e-07
 Identities = 125/581 (21%), Positives = 194/581 (33%), Gaps = 77/581 (13%)

Query: 8   QPAPASDLNLEASEAMSSDSEEAFETPESTTPVKAPPAPPPPPPEVI--PEPEVSTQPPP 65
           +P+P +    E +   +  +    + P  TT   AP  P  P P     P P    +P P
Sbjct: 379 EPSPTTPK--EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP 436

Query: 66  EEPGCGSETV---PVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIE 122
             P   + T    P P  P+  +   +    P+          K  A +    L     E
Sbjct: 437 TTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPE 496

Query: 123 LVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKS-TLSRSLSLQASDFDGASSSGNP 181
            +    T   + +    +E    T  + T + P   + T  ++ +         ++   P
Sbjct: 497 KL--APTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 554

Query: 182 EAVALAPDAYSTGSSSASSTLKRT-----KKPRPPSLKK-------KQTTKKPTETPPVK 229
                   A +T   +A +T K T     K+P P + KK         TTK+PT T   K
Sbjct: 555 APTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDK 614

Query: 230 ETQQEPDEESLVPSGENLASETKTESAKT--EGPSPALLEE----TPLEPAVGPKAACPL 283
                P + +   + +  A  T  E A T  +G +P  L+E    TP +PA  PK   P 
Sbjct: 615 PAPTTP-KGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA--PKELAPT 671

Query: 284 DSESAEGVV----PPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGL 339
            ++           P +       +P     T P   AP   E  P  +   E S     
Sbjct: 672 TTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTT--SEVSTPTTT 729

Query: 340 SVRLEFDYSEDKSSWDNQQENPPPTKKIGKK----PVAKMP-LRRPKM------KKTPEK 388
                   S D+S+ +   E  P   +   K    P  K P   +P+M      K T   
Sbjct: 730 KEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERD 789

Query: 389 LDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFD 448
           L  TP +   +P       + K T T                T++ + +    Q +    
Sbjct: 790 LRTTPETTTAAP------KMTKETAT------------TTEKTTESKITATTTQVTSTTT 831

Query: 449 PDTCDESVDPFKTSSKTP--SSPSKSPASFEIPASAMEANGVDGDGLN------KPAKKK 500
            DT    +   KT++  P  ++  K+  + EI     E         N      KP K  
Sbjct: 832 QDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPT 891

Query: 501 KTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVIS 541
           K P K  +    K PK  P    P   PTP     T P ++
Sbjct: 892 KAPKKPTS---TKKPKTMPRVRKPKTTPTPRKMTSTMPELN 929



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 96/494 (19%), Positives = 163/494 (32%), Gaps = 62/494 (12%)

Query: 32  ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQP------PPEEPGCGSETVPVPDGPRSDS 85
           E P  TTP +  P  P  P    PE    T P       P+EP   +   P P  P+   
Sbjct: 504 EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK--- 560

Query: 86  VEGSPFRP-------PSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAK 138
            E +P  P       P  +      E  P         +       +   T   + +   
Sbjct: 561 -EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTT 619

Query: 139 NQEGKVNTRRKSTDSVPISKS-TLSRSLSLQASDFDGASSSGNPEAVALAPDA----YST 193
            +     T ++   + P   + T  +  +         ++   P    LAP       ST
Sbjct: 620 PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTST 679

Query: 194 GSSSASSTLKRTKKPRPPSLKKKQTTKKPT----ETPPVKETQQEPDEESLVPSGENLAS 249
            S   + T  +   P  P      T KKP     ETPP   ++      +  P+  + + 
Sbjct: 680 TSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSP 739

Query: 250 ETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGR 309
           +  T     E P+P  LE +P EP V P    P           P         +     
Sbjct: 740 DESTPELSAE-PTPKALENSPKEPGV-PTTKTP-------AATKPEMTTTAKDKTTERDL 790

Query: 310 KTLPLTT--APEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKI 367
           +T P TT  AP+  + T + +    +S     + ++    ++D + +             
Sbjct: 791 RTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPF------------- 837

Query: 368 GKKPVAKMPLRRPKMKKTPEKLDNTP-ASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFN 426
            K    K     PK+  T + +  T   + P   A+P D        T    K       
Sbjct: 838 -KITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKK 896

Query: 427 PFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSK-------TPSSPSKSPAS--FE 477
           P +ST K +  P++ +      P     ++     +S+       T + P+++P S   E
Sbjct: 897 P-TSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVE 955

Query: 478 IPASAMEANGVDGD 491
           +   + +A G +G+
Sbjct: 956 VNPKSEDAGGAEGE 969


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 78.6 bits (192), Expect = 3e-14
 Identities = 153/698 (21%), Positives = 232/698 (33%), Gaps = 89/698 (12%)

Query: 11  PASDLNLEASEAMSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPE---PEVSTQPPP-- 65
           PA     E +   +  +    + P  TTP K  P  P  P    P+   P    +P P  
Sbjct: 319 PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTT 378

Query: 66  EEPGCGSETVPVPDGPRSDSVEGSPFRP----PSHSFSAVFDEDKPIASSGTYNLDFDNI 121
           +EP   +   P P  P+  +   +P  P    P         E  P              
Sbjct: 379 KEPAPTTPKEPAPTAPKKPA-PTTPKEPAPTTPKEPAPTTTKEPSPTTPK---------- 427

Query: 122 ELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNP 181
                    EP  +  K+      T ++   +   S  T  +  S   +     ++   P
Sbjct: 428 ---------EPAPTTTKSAP---TTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP 475

Query: 182 EAVALAPDAYSTGSSSASSTLKR-----TKKPRPPSLKK--KQTTKKPTETPPVKETQQE 234
                   A +T    A +T K      TKKP P + K+    T K+   T P K T   
Sbjct: 476 APTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 535

Query: 235 PDEESLVP-SGENLASETKTESAKT--EGPSPALLEETPLEPA-VGPKAACPLDSESAEG 290
           P  E L P + E  A  T  E A T  E P+P     TP EPA   PKAA P   +    
Sbjct: 536 P--EKLAPTTPEKPAPTTPEELAPTTPEEPTPT----TPEEPAPTTPKAAAPNTPKEPAP 589

Query: 291 VVP----PASGGGRVQNSPPVGRKTLPLTTAP----EAGEVTPSDSGGQEDSPAKGLSVR 342
             P    P +       +P     T P  TAP    E    TP     +E +P    + +
Sbjct: 590 TTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT---TTK 646

Query: 343 LEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAE 402
                + DK +    +   P T K       K P         P  L     + P+ PA 
Sbjct: 647 EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAP 706

Query: 403 PNDIP-IAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFK- 460
               P   KG  +   DK         + T+  + +P  P++     P+T   +      
Sbjct: 707 KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVST 766

Query: 461 -TSSKTPSSPSKSPASFEIPASAMEA-NGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRS 518
            T++K P++  KSP       SA      ++           KTP  T       +  ++
Sbjct: 767 PTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKT 826

Query: 519 PLSDPPSQDPTPAATPETPPVISAVVHATDEEKL-AVTNQKWTCMTVDLEADKQDYPQPS 577
              D  +   T  A P+     +     T E K+ A T Q  +  T D    K    + +
Sbjct: 827 TERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTT 886

Query: 578 DLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQALYLMFDTSQESPV 637
            L+  V  TK +  T E+          M K     P++   PK +A     ++   +P 
Sbjct: 887 TLAPKVTTTKKTITTTEI----------MNK-----PEETAKPKDRAT----NSKATTPK 927

Query: 638 KSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHPVPR 675
              P +  + PT     S ++ + +         P PR
Sbjct: 928 PQKPTKAPKKPT-----STKKPKTMPRVRKPKTTPTPR 960



 Score = 68.2 bits (165), Expect = 4e-11
 Identities = 126/605 (20%), Positives = 192/605 (31%), Gaps = 101/605 (16%)

Query: 109 ASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPIS-------KSTL 161
           A SG  N DF  +   DT  T          Q  KV+T  K T + PI+        S  
Sbjct: 129 AGSGLDNGDF-KVTTPDTSTT----------QHNKVSTSPKITTAKPINPRPSLPPNSDT 177

Query: 162 SRSLSL-----------QASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRP 210
           S+  SL           + +  +  +S+   E    A +  S   +SA      +K    
Sbjct: 178 SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK 237

Query: 211 PSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEETP 270
           P+ K + TTK P  T P + T   P E +     E   +  K+     + P+P   +  P
Sbjct: 238 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 297

Query: 271 LEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVT---PSD 327
                 PK   P  ++      P        +   P   K+ P TT  E    T   P+ 
Sbjct: 298 ----TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAP-TTPKEPAPTTPKKPAP 352

Query: 328 SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
           +  +E +P            +  K       + P PT K       K P      K  P 
Sbjct: 353 TTPKEPAP------------TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP- 399

Query: 388 KLDNTPASP-PRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYN 446
               TP  P P +P EP                       P ++      +PK P  +  
Sbjct: 400 ---TTPKEPAPTTPKEP----------------------APTTTKEPSPTTPKEPAPTTT 434

Query: 447 FDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKT 506
               T  +   P  T S   +    SP + + PA                    K P  T
Sbjct: 435 KSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPT 494

Query: 507 DTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTV-- 564
                  +  + P    P ++P P    ET P     +  T  EKLA T  +    T   
Sbjct: 495 TPKEPAPTTTKKPAPTTP-KEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPE 553

Query: 565 DLEADKQDYPQPSDLSTFVNET-KFSSPTEELDYRNSYEIEYMEKIGSSLPQD--DDAPK 621
           +L     + P P+        T K ++P               ++   + P++     PK
Sbjct: 554 ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTP------------KEPAPTTPKEPAPTTPK 601

Query: 622 KQALYLMFDTSQESPVKSSPVRMSE-------SPTPCSGSSFEETEALVNTAAKNQHPVP 674
           + A     +T+  +P  ++P  + E        P P   +     E    T  K     P
Sbjct: 602 EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP 661

Query: 675 RGLAP 679
           +G AP
Sbjct: 662 KGTAP 666



 Score = 57.0 bits (136), Expect = 9e-08
 Identities = 106/514 (20%), Positives = 169/514 (32%), Gaps = 67/514 (13%)

Query: 214 KKKQTTKKPTETPPVKETQQEPDEESLVPSGENLAS--ETKTESAKTEGPSPALLEETPL 271
           KK +T KKPT  PPV +     +  S + +G+   +  +T T        SP +    P 
Sbjct: 111 KKNRTKKKPTPKPPVVD-----EAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKP- 164

Query: 272 EPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQ 331
              + P+ + P +S++++            + S  V ++     T  E  E T ++    
Sbjct: 165 ---INPRPSLPPNSDTSK------------ETSLTVNKE-----TTVETKETTTTNKQTS 204

Query: 332 EDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPV--AKMPLRRPKMKKTPEKL 389
            D   K  S +      E +S      ++  PT K+  KP   A+   + P +    E  
Sbjct: 205 TDGKEKTTSAK------ETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPT 258

Query: 390 DNTPASP-PRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFD 448
             TP  P   +P EP    I     T        P     ++T     +PK P  +   +
Sbjct: 259 PTTPKEPASTTPKEPTPTTIKSAPTT--------PKEPAPTTTKSAPTTPKEPAPTTTKE 310

Query: 449 P-DTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTD 507
           P  T  +   P  T    P++   +P + + PA               P +   T  K  
Sbjct: 311 PAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAP----TTPKEPAPTTPKEP 366

Query: 508 TFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTVDLE 567
           T    K P       P +++P P    E  P        T  ++ A T  K    T   E
Sbjct: 367 TPTTPKEPA------PTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKE 420

Query: 568 AD--KQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQAL 625
                   P P+   +    TK  +PT       + +           P     P     
Sbjct: 421 PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP 480

Query: 626 YLMFDTSQESPVKSSPVRMSESPTPCSGSSFEET---EALVNTAAKNQHPVPRGLAPNQE 682
                T+ + P  ++P    + P P +      T   E    T  +     P+ L P   
Sbjct: 481 KKPAPTTPKEPAPTTP----KEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTP 536

Query: 683 SHL--QVPEKSSQKELEAMGLGTPSEAIEITAPE 714
             L    PEK +    E +   TP E    T  E
Sbjct: 537 EKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE 570



 Score = 53.9 bits (128), Expect = 8e-07
 Identities = 125/581 (21%), Positives = 194/581 (33%), Gaps = 77/581 (13%)

Query: 8   QPAPASDLNLEASEAMSSDSEEAFETPESTTPVKAPPAPPPPPPEVI--PEPEVSTQPPP 65
           +P+P +    E +   +  +    + P  TT   AP  P  P P     P P    +P P
Sbjct: 420 EPSPTTPK--EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP 477

Query: 66  EEPGCGSETV---PVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIE 122
             P   + T    P P  P+  +   +    P+          K  A +    L     E
Sbjct: 478 TTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPE 537

Query: 123 LVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKS-TLSRSLSLQASDFDGASSSGNP 181
            +    T   + +    +E    T  + T + P   + T  ++ +         ++   P
Sbjct: 538 KL--APTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 595

Query: 182 EAVALAPDAYSTGSSSASSTLKRT-----KKPRPPSLKK-------KQTTKKPTETPPVK 229
                   A +T   +A +T K T     K+P P + KK         TTK+PT T   K
Sbjct: 596 APTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDK 655

Query: 230 ETQQEPDEESLVPSGENLASETKTESAKT--EGPSPALLEE----TPLEPAVGPKAACPL 283
                P + +   + +  A  T  E A T  +G +P  L+E    TP +PA  PK   P 
Sbjct: 656 PAPTTP-KGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA--PKELAPT 712

Query: 284 DSESAEGVV----PPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGL 339
            ++           P +       +P     T P   AP   E  P  +   E S     
Sbjct: 713 TTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTT--SEVSTPTTT 770

Query: 340 SVRLEFDYSEDKSSWDNQQENPPPTKKIGKK----PVAKMP-LRRPKM------KKTPEK 388
                   S D+S+ +   E  P   +   K    P  K P   +P+M      K T   
Sbjct: 771 KEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERD 830

Query: 389 LDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFD 448
           L  TP +   +P       + K T T                T++ + +    Q +    
Sbjct: 831 LRTTPETTTAAP------KMTKETAT------------TTEKTTESKITATTTQVTSTTT 872

Query: 449 PDTCDESVDPFKTSSKTP--SSPSKSPASFEIPASAMEANGVDGDGLN------KPAKKK 500
            DT    +   KT++  P  ++  K+  + EI     E         N      KP K  
Sbjct: 873 QDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPT 932

Query: 501 KTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVIS 541
           K P K  +    K PK  P    P   PTP     T P ++
Sbjct: 933 KAPKKPTS---TKKPKTMPRVRKPKTTPTPRKMTSTMPELN 970



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 96/494 (19%), Positives = 163/494 (32%), Gaps = 62/494 (12%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQP------PPEEPGCGSETVPVPDGPRSDS 85
            E P  TTP +  P  P  P    PE    T P       P+EP   +   P P  P+   
Sbjct: 545  EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK--- 601

Query: 86   VEGSPFRP-------PSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAK 138
             E +P  P       P  +      E  P         +       +   T   + +   
Sbjct: 602  -EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTT 660

Query: 139  NQEGKVNTRRKSTDSVPISKS-TLSRSLSLQASDFDGASSSGNPEAVALAPDA----YST 193
             +     T ++   + P   + T  +  +         ++   P    LAP       ST
Sbjct: 661  PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTST 720

Query: 194  GSSSASSTLKRTKKPRPPSLKKKQTTKKPT----ETPPVKETQQEPDEESLVPSGENLAS 249
             S   + T  +   P  P      T KKP     ETPP   ++      +  P+  + + 
Sbjct: 721  TSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSP 780

Query: 250  ETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGR 309
            +  T     E P+P  LE +P EP V P    P           P         +     
Sbjct: 781  DESTPELSAE-PTPKALENSPKEPGV-PTTKTP-------AATKPEMTTTAKDKTTERDL 831

Query: 310  KTLPLTT--APEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKI 367
            +T P TT  AP+  + T + +    +S     + ++    ++D + +             
Sbjct: 832  RTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPF------------- 878

Query: 368  GKKPVAKMPLRRPKMKKTPEKLDNTP-ASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFN 426
             K    K     PK+  T + +  T   + P   A+P D        T    K       
Sbjct: 879  -KITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKK 937

Query: 427  PFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSK-------TPSSPSKSPAS--FE 477
            P +ST K +  P++ +      P     ++     +S+       T + P+++P S   E
Sbjct: 938  P-TSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVE 996

Query: 478  IPASAMEANGVDGD 491
            +   + +A G +G+
Sbjct: 997  VNPKSEDAGGAEGE 1010


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 78.6 bits (192), Expect = 3e-14
 Identities = 153/698 (21%), Positives = 232/698 (33%), Gaps = 89/698 (12%)

Query: 11   PASDLNLEASEAMSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPE---PEVSTQPPP-- 65
            PA     E +   +  +    + P  TTP K  P  P  P    P+   P    +P P  
Sbjct: 371  PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTT 430

Query: 66   EEPGCGSETVPVPDGPRSDSVEGSPFRP----PSHSFSAVFDEDKPIASSGTYNLDFDNI 121
            +EP   +   P P  P+  +   +P  P    P         E  P              
Sbjct: 431  KEPAPTTPKEPAPTAPKKPA-PTTPKEPAPTTPKEPAPTTTKEPSPTTPK---------- 479

Query: 122  ELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNP 181
                     EP  +  K+      T ++   +   S  T  +  S   +     ++   P
Sbjct: 480  ---------EPAPTTTKSAP---TTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP 527

Query: 182  EAVALAPDAYSTGSSSASSTLKR-----TKKPRPPSLKK--KQTTKKPTETPPVKETQQE 234
                    A +T    A +T K      TKKP P + K+    T K+   T P K T   
Sbjct: 528  APTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 587

Query: 235  PDEESLVP-SGENLASETKTESAKT--EGPSPALLEETPLEPA-VGPKAACPLDSESAEG 290
            P  E L P + E  A  T  E A T  E P+P     TP EPA   PKAA P   +    
Sbjct: 588  P--EKLAPTTPEKPAPTTPEELAPTTPEEPTPT----TPEEPAPTTPKAAAPNTPKEPAP 641

Query: 291  VVP----PASGGGRVQNSPPVGRKTLPLTTAP----EAGEVTPSDSGGQEDSPAKGLSVR 342
              P    P +       +P     T P  TAP    E    TP     +E +P    + +
Sbjct: 642  TTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT---TTK 698

Query: 343  LEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAE 402
                 + DK +    +   P T K       K P         P  L     + P+ PA 
Sbjct: 699  EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAP 758

Query: 403  PNDIP-IAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFK- 460
                P   KG  +   DK         + T+  + +P  P++     P+T   +      
Sbjct: 759  KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVST 818

Query: 461  -TSSKTPSSPSKSPASFEIPASAMEA-NGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRS 518
             T++K P++  KSP       SA      ++           KTP  T       +  ++
Sbjct: 819  PTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKT 878

Query: 519  PLSDPPSQDPTPAATPETPPVISAVVHATDEEKL-AVTNQKWTCMTVDLEADKQDYPQPS 577
               D  +   T  A P+     +     T E K+ A T Q  +  T D    K    + +
Sbjct: 879  TERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTT 938

Query: 578  DLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQALYLMFDTSQESPV 637
             L+  V  TK +  T E+          M K     P++   PK +A     ++   +P 
Sbjct: 939  TLAPKVTTTKKTITTTEI----------MNK-----PEETAKPKDRAT----NSKATTPK 979

Query: 638  KSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHPVPR 675
               P +  + PT     S ++ + +         P PR
Sbjct: 980  PQKPTKAPKKPT-----STKKPKTMPRVRKPKTTPTPR 1012



 Score = 68.2 bits (165), Expect = 4e-11
 Identities = 126/605 (20%), Positives = 192/605 (31%), Gaps = 101/605 (16%)

Query: 109 ASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPIS-------KSTL 161
           A SG  N DF  +   DT  T          Q  KV+T  K T + PI+        S  
Sbjct: 181 AGSGLDNGDF-KVTTPDTSTT----------QHNKVSTSPKITTAKPINPRPSLPPNSDT 229

Query: 162 SRSLSL-----------QASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRP 210
           S+  SL           + +  +  +S+   E    A +  S   +SA      +K    
Sbjct: 230 SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK 289

Query: 211 PSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEETP 270
           P+ K + TTK P  T P + T   P E +     E   +  K+     + P+P   +  P
Sbjct: 290 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 349

Query: 271 LEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVT---PSD 327
                 PK   P  ++      P        +   P   K+ P TT  E    T   P+ 
Sbjct: 350 ----TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAP-TTPKEPAPTTPKKPAP 404

Query: 328 SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
           +  +E +P            +  K       + P PT K       K P      K  P 
Sbjct: 405 TTPKEPAP------------TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP- 451

Query: 388 KLDNTPASP-PRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYN 446
               TP  P P +P EP                       P ++      +PK P  +  
Sbjct: 452 ---TTPKEPAPTTPKEP----------------------APTTTKEPSPTTPKEPAPTTT 486

Query: 447 FDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKT 506
               T  +   P  T S   +    SP + + PA                    K P  T
Sbjct: 487 KSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPT 546

Query: 507 DTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTV-- 564
                  +  + P    P ++P P    ET P     +  T  EKLA T  +    T   
Sbjct: 547 TPKEPAPTTTKKPAPTTP-KEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPE 605

Query: 565 DLEADKQDYPQPSDLSTFVNET-KFSSPTEELDYRNSYEIEYMEKIGSSLPQD--DDAPK 621
           +L     + P P+        T K ++P               ++   + P++     PK
Sbjct: 606 ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTP------------KEPAPTTPKEPAPTTPK 653

Query: 622 KQALYLMFDTSQESPVKSSPVRMSE-------SPTPCSGSSFEETEALVNTAAKNQHPVP 674
           + A     +T+  +P  ++P  + E        P P   +     E    T  K     P
Sbjct: 654 EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP 713

Query: 675 RGLAP 679
           +G AP
Sbjct: 714 KGTAP 718



 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 125/613 (20%), Positives = 206/613 (33%), Gaps = 87/613 (14%)

Query: 129 TLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDF-DGASSSGNPEAVALA 187
           T  P +  A    G   T + +T   P   +       +++ +  +  S S N E+ +  
Sbjct: 70  TSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSS-- 127

Query: 188 PDAYSTGSSSASSTLKRTKKPRPPSL-------------KKKQTTKKPTETPPVKETQQE 234
               S+ SSS+SST+++ K  +  +              KK +T KKPT  PPV +    
Sbjct: 128 ----SSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVD---- 179

Query: 235 PDEESLVPSGENLAS--ETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVV 292
            +  S + +G+   +  +T T        SP +    P    + P+ + P +S++++   
Sbjct: 180 -EAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKP----INPRPSLPPNSDTSK--- 231

Query: 293 PPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKS 352
                    + S  V ++     T  E  E T ++     D   K  S +      E +S
Sbjct: 232 ---------ETSLTVNKE-----TTVETKETTTTNKQTSTDGKEKTTSAK------ETQS 271

Query: 353 SWDNQQENPPPTKKIGKKPV--AKMPLRRPKMKKTPEKLDNTPASP-PRSPAEPNDIPIA 409
                 ++  PT K+  KP   A+   + P +    E    TP  P   +P EP    I 
Sbjct: 272 IEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIK 331

Query: 410 KGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDP-DTCDESVDPFKTSSKTPSS 468
               T        P     ++T     +PK P  +   +P  T  +   P  T    P++
Sbjct: 332 SAPTT--------PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTT 383

Query: 469 PSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDP 528
              +P + + PA               P +   T  K  T    K P       P +++P
Sbjct: 384 TKSAPTTPKEPAPTTPKKPAP----TTPKEPAPTTPKEPTPTTPKEPA------PTTKEP 433

Query: 529 TPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTVDLEAD--KQDYPQPSDLSTFVNET 586
            P    E  P        T  ++ A T  K    T   E        P P+   +    T
Sbjct: 434 APTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 493

Query: 587 KFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQALYLMFDTSQESPVKSSPVRMSE 646
           K  +PT       + +           P     P          T+ + P  ++P    +
Sbjct: 494 KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTP----K 549

Query: 647 SPTPCSGSSFEET---EALVNTAAKNQHPVPRGLAPNQESHL--QVPEKSSQKELEAMGL 701
            P P +      T   E    T  +     P+ L P     L    PEK +    E +  
Sbjct: 550 EPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP 609

Query: 702 GTPSEAIEITAPE 714
            TP E    T  E
Sbjct: 610 TTPEEPTPTTPEE 622



 Score = 53.9 bits (128), Expect = 8e-07
 Identities = 125/581 (21%), Positives = 194/581 (33%), Gaps = 77/581 (13%)

Query: 8    QPAPASDLNLEASEAMSSDSEEAFETPESTTPVKAPPAPPPPPPEVI--PEPEVSTQPPP 65
            +P+P +    E +   +  +    + P  TT   AP  P  P P     P P    +P P
Sbjct: 472  EPSPTTPK--EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP 529

Query: 66   EEPGCGSETV---PVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIE 122
              P   + T    P P  P+  +   +    P+          K  A +    L     E
Sbjct: 530  TTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPE 589

Query: 123  LVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKS-TLSRSLSLQASDFDGASSSGNP 181
             +    T   + +    +E    T  + T + P   + T  ++ +         ++   P
Sbjct: 590  KL--APTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 647

Query: 182  EAVALAPDAYSTGSSSASSTLKRT-----KKPRPPSLKK-------KQTTKKPTETPPVK 229
                    A +T   +A +T K T     K+P P + KK         TTK+PT T   K
Sbjct: 648  APTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDK 707

Query: 230  ETQQEPDEESLVPSGENLASETKTESAKT--EGPSPALLEE----TPLEPAVGPKAACPL 283
                 P + +   + +  A  T  E A T  +G +P  L+E    TP +PA  PK   P 
Sbjct: 708  PAPTTP-KGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA--PKELAPT 764

Query: 284  DSESAEGVV----PPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGL 339
             ++           P +       +P     T P   AP   E  P  +   E S     
Sbjct: 765  TTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTT--SEVSTPTTT 822

Query: 340  SVRLEFDYSEDKSSWDNQQENPPPTKKIGKK----PVAKMP-LRRPKM------KKTPEK 388
                    S D+S+ +   E  P   +   K    P  K P   +P+M      K T   
Sbjct: 823  KEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERD 882

Query: 389  LDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFD 448
            L  TP +   +P       + K T T                T++ + +    Q +    
Sbjct: 883  LRTTPETTTAAP------KMTKETAT------------TTEKTTESKITATTTQVTSTTT 924

Query: 449  PDTCDESVDPFKTSSKTP--SSPSKSPASFEIPASAMEANGVDGDGLN------KPAKKK 500
             DT    +   KT++  P  ++  K+  + EI     E         N      KP K  
Sbjct: 925  QDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPT 984

Query: 501  KTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVIS 541
            K P K  +    K PK  P    P   PTP     T P ++
Sbjct: 985  KAPKKPTS---TKKPKTMPRVRKPKTTPTPRKMTSTMPELN 1022



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 96/494 (19%), Positives = 163/494 (32%), Gaps = 62/494 (12%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQP------PPEEPGCGSETVPVPDGPRSDS 85
            E P  TTP +  P  P  P    PE    T P       P+EP   +   P P  P+   
Sbjct: 597  EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK--- 653

Query: 86   VEGSPFRP-------PSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAK 138
             E +P  P       P  +      E  P         +       +   T   + +   
Sbjct: 654  -EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTT 712

Query: 139  NQEGKVNTRRKSTDSVPISKS-TLSRSLSLQASDFDGASSSGNPEAVALAPDA----YST 193
             +     T ++   + P   + T  +  +         ++   P    LAP       ST
Sbjct: 713  PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTST 772

Query: 194  GSSSASSTLKRTKKPRPPSLKKKQTTKKPT----ETPPVKETQQEPDEESLVPSGENLAS 249
             S   + T  +   P  P      T KKP     ETPP   ++      +  P+  + + 
Sbjct: 773  TSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSP 832

Query: 250  ETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGR 309
            +  T     E P+P  LE +P EP V P    P           P         +     
Sbjct: 833  DESTPELSAE-PTPKALENSPKEPGV-PTTKTP-------AATKPEMTTTAKDKTTERDL 883

Query: 310  KTLPLTT--APEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKI 367
            +T P TT  AP+  + T + +    +S     + ++    ++D + +             
Sbjct: 884  RTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPF------------- 930

Query: 368  GKKPVAKMPLRRPKMKKTPEKLDNTP-ASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFN 426
             K    K     PK+  T + +  T   + P   A+P D        T    K       
Sbjct: 931  -KITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKK 989

Query: 427  PFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSK-------TPSSPSKSPAS--FE 477
            P +ST K +  P++ +      P     ++     +S+       T + P+++P S   E
Sbjct: 990  P-TSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVE 1048

Query: 478  IPASAMEANGVDGD 491
            +   + +A G +G+
Sbjct: 1049 VNPKSEDAGGAEGE 1062


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 78.6 bits (192), Expect = 3e-14
 Identities = 153/698 (21%), Positives = 232/698 (33%), Gaps = 89/698 (12%)

Query: 11   PASDLNLEASEAMSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPE---PEVSTQPPP-- 65
            PA     E +   +  +    + P  TTP K  P  P  P    P+   P    +P P  
Sbjct: 412  PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTT 471

Query: 66   EEPGCGSETVPVPDGPRSDSVEGSPFRP----PSHSFSAVFDEDKPIASSGTYNLDFDNI 121
            +EP   +   P P  P+  +   +P  P    P         E  P              
Sbjct: 472  KEPAPTTPKEPAPTAPKKPA-PTTPKEPAPTTPKEPAPTTTKEPSPTTPK---------- 520

Query: 122  ELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNP 181
                     EP  +  K+      T ++   +   S  T  +  S   +     ++   P
Sbjct: 521  ---------EPAPTTTKSAP---TTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP 568

Query: 182  EAVALAPDAYSTGSSSASSTLKR-----TKKPRPPSLKK--KQTTKKPTETPPVKETQQE 234
                    A +T    A +T K      TKKP P + K+    T K+   T P K T   
Sbjct: 569  APTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 628

Query: 235  PDEESLVP-SGENLASETKTESAKT--EGPSPALLEETPLEPA-VGPKAACPLDSESAEG 290
            P  E L P + E  A  T  E A T  E P+P     TP EPA   PKAA P   +    
Sbjct: 629  P--EKLAPTTPEKPAPTTPEELAPTTPEEPTPT----TPEEPAPTTPKAAAPNTPKEPAP 682

Query: 291  VVP----PASGGGRVQNSPPVGRKTLPLTTAP----EAGEVTPSDSGGQEDSPAKGLSVR 342
              P    P +       +P     T P  TAP    E    TP     +E +P    + +
Sbjct: 683  TTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT---TTK 739

Query: 343  LEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAE 402
                 + DK +    +   P T K       K P         P  L     + P+ PA 
Sbjct: 740  EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAP 799

Query: 403  PNDIP-IAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFK- 460
                P   KG  +   DK         + T+  + +P  P++     P+T   +      
Sbjct: 800  KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVST 859

Query: 461  -TSSKTPSSPSKSPASFEIPASAMEA-NGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRS 518
             T++K P++  KSP       SA      ++           KTP  T       +  ++
Sbjct: 860  PTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKT 919

Query: 519  PLSDPPSQDPTPAATPETPPVISAVVHATDEEKL-AVTNQKWTCMTVDLEADKQDYPQPS 577
               D  +   T  A P+     +     T E K+ A T Q  +  T D    K    + +
Sbjct: 920  TERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTT 979

Query: 578  DLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQALYLMFDTSQESPV 637
             L+  V  TK +  T E+          M K     P++   PK +A     ++   +P 
Sbjct: 980  TLAPKVTTTKKTITTTEI----------MNK-----PEETAKPKDRAT----NSKATTPK 1020

Query: 638  KSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHPVPR 675
               P +  + PT     S ++ + +         P PR
Sbjct: 1021 PQKPTKAPKKPT-----STKKPKTMPRVRKPKTTPTPR 1053



 Score = 68.2 bits (165), Expect = 4e-11
 Identities = 126/605 (20%), Positives = 192/605 (31%), Gaps = 101/605 (16%)

Query: 109 ASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPIS-------KSTL 161
           A SG  N DF  +   DT  T          Q  KV+T  K T + PI+        S  
Sbjct: 222 AGSGLDNGDF-KVTTPDTSTT----------QHNKVSTSPKITTAKPINPRPSLPPNSDT 270

Query: 162 SRSLSL-----------QASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRP 210
           S+  SL           + +  +  +S+   E    A +  S   +SA      +K    
Sbjct: 271 SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK 330

Query: 211 PSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEETP 270
           P+ K + TTK P  T P + T   P E +     E   +  K+     + P+P   +  P
Sbjct: 331 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 390

Query: 271 LEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVT---PSD 327
                 PK   P  ++      P        +   P   K+ P TT  E    T   P+ 
Sbjct: 391 ----TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAP-TTPKEPAPTTPKKPAP 445

Query: 328 SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
           +  +E +P            +  K       + P PT K       K P      K  P 
Sbjct: 446 TTPKEPAP------------TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP- 492

Query: 388 KLDNTPASP-PRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYN 446
               TP  P P +P EP                       P ++      +PK P  +  
Sbjct: 493 ---TTPKEPAPTTPKEP----------------------APTTTKEPSPTTPKEPAPTTT 527

Query: 447 FDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKT 506
               T  +   P  T S   +    SP + + PA                    K P  T
Sbjct: 528 KSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPT 587

Query: 507 DTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTV-- 564
                  +  + P    P ++P P    ET P     +  T  EKLA T  +    T   
Sbjct: 588 TPKEPAPTTTKKPAPTTP-KEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPE 646

Query: 565 DLEADKQDYPQPSDLSTFVNET-KFSSPTEELDYRNSYEIEYMEKIGSSLPQD--DDAPK 621
           +L     + P P+        T K ++P               ++   + P++     PK
Sbjct: 647 ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTP------------KEPAPTTPKEPAPTTPK 694

Query: 622 KQALYLMFDTSQESPVKSSPVRMSE-------SPTPCSGSSFEETEALVNTAAKNQHPVP 674
           + A     +T+  +P  ++P  + E        P P   +     E    T  K     P
Sbjct: 695 EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP 754

Query: 675 RGLAP 679
           +G AP
Sbjct: 755 KGTAP 759



 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 125/613 (20%), Positives = 206/613 (33%), Gaps = 87/613 (14%)

Query: 129 TLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDF-DGASSSGNPEAVALA 187
           T  P +  A    G   T + +T   P   +       +++ +  +  S S N E+ +  
Sbjct: 111 TSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSS-- 168

Query: 188 PDAYSTGSSSASSTLKRTKKPRPPSL-------------KKKQTTKKPTETPPVKETQQE 234
               S+ SSS+SST+++ K  +  +              KK +T KKPT  PPV +    
Sbjct: 169 ----SSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVD---- 220

Query: 235 PDEESLVPSGENLAS--ETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVV 292
            +  S + +G+   +  +T T        SP +    P    + P+ + P +S++++   
Sbjct: 221 -EAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKP----INPRPSLPPNSDTSK--- 272

Query: 293 PPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKS 352
                    + S  V ++     T  E  E T ++     D   K  S +      E +S
Sbjct: 273 ---------ETSLTVNKE-----TTVETKETTTTNKQTSTDGKEKTTSAK------ETQS 312

Query: 353 SWDNQQENPPPTKKIGKKPV--AKMPLRRPKMKKTPEKLDNTPASP-PRSPAEPNDIPIA 409
                 ++  PT K+  KP   A+   + P +    E    TP  P   +P EP    I 
Sbjct: 313 IEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIK 372

Query: 410 KGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDP-DTCDESVDPFKTSSKTPSS 468
               T        P     ++T     +PK P  +   +P  T  +   P  T    P++
Sbjct: 373 SAPTT--------PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTT 424

Query: 469 PSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDP 528
              +P + + PA               P +   T  K  T    K P       P +++P
Sbjct: 425 TKSAPTTPKEPAPTTPKKPAP----TTPKEPAPTTPKEPTPTTPKEPA------PTTKEP 474

Query: 529 TPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTVDLEAD--KQDYPQPSDLSTFVNET 586
            P    E  P        T  ++ A T  K    T   E        P P+   +    T
Sbjct: 475 APTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 534

Query: 587 KFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQALYLMFDTSQESPVKSSPVRMSE 646
           K  +PT       + +           P     P          T+ + P  ++P    +
Sbjct: 535 KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTP----K 590

Query: 647 SPTPCSGSSFEET---EALVNTAAKNQHPVPRGLAPNQESHL--QVPEKSSQKELEAMGL 701
            P P +      T   E    T  +     P+ L P     L    PEK +    E +  
Sbjct: 591 EPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP 650

Query: 702 GTPSEAIEITAPE 714
            TP E    T  E
Sbjct: 651 TTPEEPTPTTPEE 663



 Score = 53.9 bits (128), Expect = 8e-07
 Identities = 125/581 (21%), Positives = 194/581 (33%), Gaps = 77/581 (13%)

Query: 8    QPAPASDLNLEASEAMSSDSEEAFETPESTTPVKAPPAPPPPPPEVI--PEPEVSTQPPP 65
            +P+P +    E +   +  +    + P  TT   AP  P  P P     P P    +P P
Sbjct: 513  EPSPTTPK--EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP 570

Query: 66   EEPGCGSETV---PVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIE 122
              P   + T    P P  P+  +   +    P+          K  A +    L     E
Sbjct: 571  TTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPE 630

Query: 123  LVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKS-TLSRSLSLQASDFDGASSSGNP 181
             +    T   + +    +E    T  + T + P   + T  ++ +         ++   P
Sbjct: 631  KL--APTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 688

Query: 182  EAVALAPDAYSTGSSSASSTLKRT-----KKPRPPSLKK-------KQTTKKPTETPPVK 229
                    A +T   +A +T K T     K+P P + KK         TTK+PT T   K
Sbjct: 689  APTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDK 748

Query: 230  ETQQEPDEESLVPSGENLASETKTESAKT--EGPSPALLEE----TPLEPAVGPKAACPL 283
                 P + +   + +  A  T  E A T  +G +P  L+E    TP +PA  PK   P 
Sbjct: 749  PAPTTP-KGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA--PKELAPT 805

Query: 284  DSESAEGVV----PPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGL 339
             ++           P +       +P     T P   AP   E  P  +   E S     
Sbjct: 806  TTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTT--SEVSTPTTT 863

Query: 340  SVRLEFDYSEDKSSWDNQQENPPPTKKIGKK----PVAKMP-LRRPKM------KKTPEK 388
                    S D+S+ +   E  P   +   K    P  K P   +P+M      K T   
Sbjct: 864  KEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERD 923

Query: 389  LDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFD 448
            L  TP +   +P       + K T T                T++ + +    Q +    
Sbjct: 924  LRTTPETTTAAP------KMTKETAT------------TTEKTTESKITATTTQVTSTTT 965

Query: 449  PDTCDESVDPFKTSSKTP--SSPSKSPASFEIPASAMEANGVDGDGLN------KPAKKK 500
             DT    +   KT++  P  ++  K+  + EI     E         N      KP K  
Sbjct: 966  QDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPT 1025

Query: 501  KTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVIS 541
            K P K  +    K PK  P    P   PTP     T P ++
Sbjct: 1026 KAPKKPTS---TKKPKTMPRVRKPKTTPTPRKMTSTMPELN 1063



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 96/494 (19%), Positives = 163/494 (32%), Gaps = 62/494 (12%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQP------PPEEPGCGSETVPVPDGPRSDS 85
            E P  TTP +  P  P  P    PE    T P       P+EP   +   P P  P+   
Sbjct: 638  EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK--- 694

Query: 86   VEGSPFRP-------PSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAK 138
             E +P  P       P  +      E  P         +       +   T   + +   
Sbjct: 695  -EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTT 753

Query: 139  NQEGKVNTRRKSTDSVPISKS-TLSRSLSLQASDFDGASSSGNPEAVALAPDA----YST 193
             +     T ++   + P   + T  +  +         ++   P    LAP       ST
Sbjct: 754  PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTST 813

Query: 194  GSSSASSTLKRTKKPRPPSLKKKQTTKKPT----ETPPVKETQQEPDEESLVPSGENLAS 249
             S   + T  +   P  P      T KKP     ETPP   ++      +  P+  + + 
Sbjct: 814  TSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSP 873

Query: 250  ETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGR 309
            +  T     E P+P  LE +P EP V P    P           P         +     
Sbjct: 874  DESTPELSAE-PTPKALENSPKEPGV-PTTKTP-------AATKPEMTTTAKDKTTERDL 924

Query: 310  KTLPLTT--APEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKI 367
            +T P TT  AP+  + T + +    +S     + ++    ++D + +             
Sbjct: 925  RTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPF------------- 971

Query: 368  GKKPVAKMPLRRPKMKKTPEKLDNTP-ASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFN 426
             K    K     PK+  T + +  T   + P   A+P D        T    K       
Sbjct: 972  -KITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKK 1030

Query: 427  PFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSK-------TPSSPSKSPAS--FE 477
            P +ST K +  P++ +      P     ++     +S+       T + P+++P S   E
Sbjct: 1031 P-TSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVE 1089

Query: 478  IPASAMEANGVDGD 491
            +   + +A G +G+
Sbjct: 1090 VNPKSEDAGGAEGE 1103


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 70.5 bits (171), Expect = 8e-12
 Identities = 146/586 (24%), Positives = 201/586 (34%), Gaps = 105/586 (17%)

Query: 34    PESTTPV---KAPPAPPPP----PPEVIPEPEVSTQPP--PEEPGCGSETVP---VPDGP 81
             PE   PV   K P APPP     P EV+PE +V   PP  PE P      VP   VP+  
Sbjct: 10506 PEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKK 10565

Query: 82    RSDSVEGSPFRPPSHSFSAVFD--EDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKN 139
               +++   P  PP     A  +   +K + ++     +   +++        P A     
Sbjct: 10566 VPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKV--------PEAPKEVV 10617

Query: 140   QEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGA----------SSSGNPEAVAL-AP 188
              E KV         VP +K      +++       A               PE VAL  P
Sbjct: 10618 PEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEP 10677

Query: 189   DAYSTGSSSASSTLKRTKKPRPPSLKKKQ---TTKKPTETPPVK--ETQQEPDEESLVPS 243
              A        ++  + T  P+ P  +KK      KKP E PPVK  E  +E   E  VP 
Sbjct: 10678 PAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKP-ELPPVKVPEVPKEVVPEKKVP- 10735

Query: 244   GENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQN 303
                          K E P PA + E P E     K A P   E     VPPA     V  
Sbjct: 10736 --------LVVPKKPEAP-PAKVPEVPKEVVPEKKVAVPKKPE-----VPPAK-VPEVPK 10780

Query: 304   SPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKS---SWDNQQEN 360
              P +  K  P    PE  E  P +   + +  A    +  E    E+K    + + + E 
Sbjct: 10781 KPVLEEK--PAVPVPERAESPPPEVYEEPEEIAPEEEIAPE----EEKPVPVAEEEEPEV 10834

Query: 361   PPPT-----KKI---GKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIP----- 407
             PPP      KKI    K PV K P   P  +  PEK+   P   PR P  P   P     
Sbjct: 10835 PPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVK 10894

Query: 408   --------IAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKL-------PQQSYNFD---- 448
                     I K          +     P       ++  KL       P++         
Sbjct: 10895 EKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLR 10954

Query: 449   --PDTCDESVDPFKTSS-KTPSSPSKSP----ASFEIPASAMEANGVDGDGLNKPAKKKK 501
               P+  +  V+P K    K P+ P   P       E+P        +  +    P  K  
Sbjct: 10955 KRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIP-EPTKVPEIKPA 11013

Query: 502   TPLKTDTFRVKKSPKRSPLSDPPSQ-DPTPAATPETPPVISAVVHA 546
              PL     + K   +   +  PP + +PTP A P T PV+     A
Sbjct: 11014 IPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKAEA 11059



 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 127/563 (22%), Positives = 176/563 (31%), Gaps = 92/563 (16%)

Query: 25    SDSEEAFETPESTTPVKAPPAPPPP------------PPEVIPEPEVSTQPP--PEEPGC 70
             S   E  E P+   P K  PA PP             P EV+PE +V   PP  PE P  
Sbjct: 10576 SPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPT 10635

Query: 71    GSETVP---VPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTF 127
                 VP   VP+    +++   P  PP      VF+E + +A      L+    E+V   
Sbjct: 10636 KVPEVPKVAVPEKKVPEAIPPKPESPPPE----VFEEPEEVA------LEEPPAEVV--- 10682

Query: 128   QTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALA 187
             +  EP A        K     K   +V   K  L   + +     +       P  V   
Sbjct: 10683 EEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELP-PVKVPEVPKEVVPEKKVPLVVPKK 10741

Query: 188   PDAYSTGSSSA------SSTLKRTKKPRPPSLKKKQTTKKPT--ETP--PVKETQQEP-- 235
             P+A                 +   KKP  P  K  +  KKP   E P  PV E  + P  
Sbjct: 10742 PEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPP 10801

Query: 236   ----DEESLVPSGENLASETK----TESAKTEGPSPALLEE------TPLEPAVGPKAAC 281
                 + E + P  E    E K     E  + E P PA+ EE          P +    A 
Sbjct: 10802 EVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAP 10861

Query: 282   PLDSESAEGVVPPASGGGRVQNSPPV-----------GRKTLPLTTAPEAGEVTPSDSGG 330
             P      E V+       R    PP              K +P    PE  +V       
Sbjct: 10862 PPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQV------- 10914

Query: 331   QEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLD 390
                 P K     L+    E K      +  P P +++  K V +      + K  P+KL+
Sbjct: 10915 ----PEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLE 10970

Query: 391   N-----TPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSY 445
                    P  PP  P E  ++P          +    P   P       +  PK   +  
Sbjct: 10971 KVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVK 11030

Query: 446   NFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLK 505
                P   +    P       P    K+ A      +A     + G         KKTP  
Sbjct: 11031 TIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKG-------VPKKTPSP 11083

Query: 506   TDTFRVKKSPKRSPLSDPPSQDP 528
              +  R K  P  S    PP + P
Sbjct: 11084 IEAERRKLRP-GSGGEKPPDEAP 11105



 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 153/754 (20%), Positives = 255/754 (33%), Gaps = 153/754 (20%)

Query: 26    DSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRSDS 85
             + EE    PE   PVK  P  P P     P  +V  +  PEE       VPVP   +   
Sbjct: 9781  EHEEYITEPEKPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEK------VPVPIPKK--- 9831

Query: 86    VEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQ----- 140
             ++  P + P      VF+E   I+           I   +  Q  EP A           
Sbjct: 9832  LKPPPPKVPEEP-KKVFEEKIRIS-----------ITKREKEQVTEPAAKVPMKPKRVVA 9879

Query: 141   EGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASS 200
             E KV   RK   + P+    + + L  +   F+    +   E +    + Y        +
Sbjct: 9880  EEKVPVPRKEV-APPVRVPEVPKELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFIT 9938

Query: 201   T--------LKRTKKPRPPSLKKKQTTKKPT--ETPPVK--ETQQEPDEE--SLVPSGEN 246
                      +K  + PR P  ++K+    P   E PP K  E  ++P+E+   L+P  E 
Sbjct: 9939  EEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEK 9998

Query: 247   LASETKTESAKTEGPS--------------PALLEETPLEPAVGPKAACPLDS--ESAEG 290
                    E  K   P               PA + E P +P    K   P     E+   
Sbjct: 9999  PPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPA 10058

Query: 291   VVP------------PASGGGRVQNSP---PVGRKTLPLTTA------------------ 317
              VP            P     +V+  P   P  R+ +P+  A                  
Sbjct: 10059 KVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEE 10118

Query: 318   --PEAGEVTPSDS----------GGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTK 365
               PE  EV P +             +E+ P +   V  E +Y  ++  +  ++E  P   
Sbjct: 10119 VLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEV- 10177

Query: 366   KIGKKPVAKMPLRRPKMKK--------TPEKLDNTPASPPRSP--AEPNDIPIAKGTYTF 415
                 KP   +P   P++KK         P+K +  PA  P  P   E   I + K     
Sbjct: 10178 ----KPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVL 10233

Query: 416   DIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPAS 475
              ++  ++P   P S     +E P + +      P        P       P +P+  P  
Sbjct: 10234 PVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRV------PEVIKKAVPEAPTPVPKK 10287

Query: 476   FEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPE 535
              E P  A  +  +  + +  P +KK+ P        KK P++  L   P ++  P A   
Sbjct: 10288 VEAP-PAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVL--VPKKEAVPPAKGR 10344

Query: 536   TPPVISAVVHATDEEKLAVTNQKWTCMTVDLEADKQDYPQPSDLSTFVNETKFSSPTEEL 595
             T            EEK++V  ++   +   LE +  +    +++     E +F    E  
Sbjct: 10345 T----------VLEEKVSVAFRQEVVVKERLELEVVE----AEVEEIPEEEEFHEVEEYF 10390

Query: 596   DYRNSYEIEYMEKIGSSLPQDDDAPKKQALYLMFDTSQESPVKSSPVRMSESPTPCSGSS 655
             +    +E+E   K+     +++   +K    +    ++E  V   P    + P       
Sbjct: 10391 EEGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGP------- 10443

Query: 656   FEETEALVNTAAKNQHPVPRGLAPNQESHLQVPE 689
              E +E ++          P  + P +E   +VPE
Sbjct: 10444 -EISEKIIPPKKP-----PTKVVPRKEPPAKVPE 10471



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 160/775 (20%), Positives = 264/775 (34%), Gaps = 135/775 (17%)

Query: 8     QPAPASDLNLEASEAMSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPE--PEVSTQPPP 65
             +P P   + +   + + +   +  E P+   P K  P P P   E  P   PEV  +  P
Sbjct: 10010 KPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIP 10069

Query: 66    EEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVD 125
             EE     +  PVP       VE  P + P            P+A      + F+  E+V 
Sbjct: 10070 EE----KKPTPVP-----KKVEAPPPKVPKKREPV----PVPVALPQEEEVLFEE-EIVP 10115

Query: 126   TFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFD-GASSSGNPEAV 184
               + L P   +   +E +V         +P  +  L     +   + +        PE  
Sbjct: 10116 EEEVL-PEEEEVLPEEEEV---------LPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEE 10165

Query: 185   ALAPDAYSTGSSSASSTLKRTKKPRP-PSLKKKQTTKK----------PTETPPVKETQQ 233
                P+              +   P P P +KKK T KK          P + P V +  +
Sbjct: 10166 EFVPE-----EEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVE 10220

Query: 234   E-----PDEESLVP---SGENLASETKTESAKTEGPSPALLEET--PLEPAVGPKAACPL 283
             E     P EE ++P   + E        E    E PS   +EE   P  P V  KA    
Sbjct: 10221 EKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEA 10280

Query: 284   DSESAEGV-VPPASGGGRVQNSP---PVGRKTLPLTTAPEAGEVTPSDS----GGQEDSP 335
              +   + V  PPA    ++       PV +K  P    PE  +  P         +   P
Sbjct: 10281 PTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKEAVPP 10340

Query: 336   AKGLSV-----------------RLEFDYSEDKSSWDNQQENPPPTKKIGK-------KP 371
             AKG +V                 RLE +  E +     ++E     ++  +       + 
Sbjct: 10341 AKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYFEEGEFHEVEE 10400

Query: 372   VAKMPLRRPKMKKTPEKLDNT--------------PASPPRSPAEPNDIPIAKGTYTFDI 417
               K+   R + +   EK+                 P +PP+ P     I   K   T  +
Sbjct: 10401 FIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEKIIPPKKPPTKVV 10460

Query: 418   DKWDDPNFNP-FSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKT--SSKTPSSPSKSPA 474
              + + P   P       ++E  ++P++     P    E + P +     K P  P+K P 
Sbjct: 10461 PRKEPPAKVPEVPKKIVVEEKVRVPEEP-RVPPTKVPEVLPPKEVVPEKKVPVPPAKKPE 10519

Query: 475   S--FEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSP-KRSPLSDPPSQDPTPA 531
             +   ++P +  E        +  P K +  P K         P K+ P + PP  +  P 
Sbjct: 10520 APPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPP 10579

Query: 532   ATPETPP--VISAVVHATDEEKLAVTNQKWTCMTVDLEADKQDYPQPSDLSTFVNETKFS 589
               PE P   V    V A   +K  VT  K      ++  +K+  P P      V  TK  
Sbjct: 10580 EVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKK-VPVPPPKKPEVPPTKVP 10638

Query: 590   SPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQALYLMFDTSQESPVKSSPVRMSESPT 649
                +             +K+  ++P   ++P  +    +F+  +E  ++  P  + E P 
Sbjct: 10639 EVPKVAVPE--------KKVPEAIPPKPESPPPE----VFEEPEEVALEEPPAEVVEEPE 10686

Query: 650   PCS--------GSSFEETEALVNTAAKNQHP------VPRGLAPNQESHLQVPEK 690
             P +             E +A    A K + P      VP+ + P ++  L VP+K
Sbjct: 10687 PAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKK 10741



 Score = 50.8 bits (120), Expect = 6e-06
 Identities = 130/616 (21%), Positives = 217/616 (35%), Gaps = 72/616 (11%)

Query: 206   KKPRPPSLKKKQTTKKPTETPP---VKETQQEPDEESLVPSGENLASETKTESAKTEGPS 262
             KKP    + +K+   K  E P    V+E  + P+E  + P          T+  +   P 
Sbjct: 10453 KKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPP----------TKVPEVLPPK 10502

Query: 263   PALLEE-TPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAG 321
               + E+  P+ PA  P+A  P   E+ + VVP      +    PP  +  +P T  PE  
Sbjct: 10503 EVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPE-----KKVPVPPPKKPEVPPTKVPEVP 10557

Query: 322   EVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPK 381
             +    +    E  P K  S   E   +  +   + +    PP     KKP    P++ P+
Sbjct: 10558 KAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPP-----KKPEV-TPVKVPE 10611

Query: 382   MKK--TPEKLDNTPASPPRSP-AEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESP 438
               K   PEK    P  PP+ P   P  +P        ++ K   P      +     ESP
Sbjct: 10612 APKEVVPEK--KVPVPPPKKPEVPPTKVP--------EVPKVAVPEKKVPEAIPPKPESP 10661

Query: 439   KLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAK 498
               P + +    +   E           P++P +     + P    +A  V         K
Sbjct: 10662 --PPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAV------VAKK 10713

Query: 499   KKKTPLKTDTFRVKKSP-KRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTNQ 557
              +  P+K      +  P K+ PL  P   +  PA  PE P  +        E+K+AV  +
Sbjct: 10714 PELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEV------VPEKKVAVPKK 10767

Query: 558   KWTCMTVDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQ-- 615
                      E  K+  P   +        +  SP  E+ Y    EI   E+I     +  
Sbjct: 10768 PEVPPAKVPEVPKK--PVLEEKPAVPVPERAESPPPEV-YEEPEEIAPEEEIAPEEEKPV 10824

Query: 616   ---DDDAPKKQALYLMFDTSQESPVKSSPV-RMSESPTPCSGSSFEETEALVNTAAKNQH 671
                +++ P+     +  +  +  P K  PV +  E+P P       E E ++        
Sbjct: 10825 PVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPP----KEPEPEKVIEKPKLKPR 10880

Query: 672   PVPRGLAPN----QESHLQVPEKSSQKELEAMGLGTPSEAIEITAPEGSFASADALLSRL 727
             P P   AP     +E   Q+     +K  E   +    E   +  P G       L  R 
Sbjct: 10881 PPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERK 10940

Query: 728   AHPVSLCGALDYLEPDLAEKNPPLFAQKLQEELEFAIMRIEALKLARQIALASRSHQDAK 787
               P         L     E+ P +  +KL++  + A+      K   ++ + + + ++  
Sbjct: 10941 PEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRE-- 10998

Query: 788   REAAHPTDVSISKTAL 803
             R+   PT V   K A+
Sbjct: 10999 RKIPEPTKVPEIKPAI 11014



 Score = 50.4 bits (119), Expect = 8e-06
 Identities = 149/777 (19%), Positives = 256/777 (32%), Gaps = 142/777 (18%)

Query: 21   EAMSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVS----TQPPPEEPGCGSETVP 76
            E +    E   E+ E   P K P    PPPP+VI +P +     T    EE       VP
Sbjct: 9148 EVIQVQKEVYEESHERKVPAKVPEKKAPPPPKVIKKPVIEKIEKTSRRMEEEKVQVTKVP 9207

Query: 77   ------VPDGPRSDSVEGSPFR---PPSHSFSAVFDEDKPIASSGTYNLDFDNIELVD-- 125
                  VP  P    V+        P  H+   V  E+K   +S T       +  V   
Sbjct: 9208 EVSKKIVPQKPSRTPVQEEVIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKE 9267

Query: 126  --TFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEA 183
              T + +    S       KV    +      ++   + + +   A           PE 
Sbjct: 9268 IVTEEKIHVAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEE 9327

Query: 184  VALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPS 243
                P      ++           P+ P + KK   ++    P  K+ +  P +   V  
Sbjct: 9328 KKPVPVPKKEPAAP----------PKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQK 9377

Query: 244  GENLASETKTESAKTEGPSPAL------------------LEETPLEPAVGPKAACPLDS 285
            G     +    + + E P PA+                   EE P  P V      P+  
Sbjct: 9378 GVVTEEKITIVTQREESPPPAVPEIPKKKVPEERKPVPRKEEEVPPPPKVPALPKKPVPE 9437

Query: 286  ESAEGVVPPASGGGRVQNSPP----VGRKTL----------PLTTA-PEAGEVTPSDSGG 330
            E     VP A      + +PP    V +KT+           L+ A P+  EVT  +   
Sbjct: 9438 EKVAVPVPVA------KKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSA 9491

Query: 331  QED----SPAKGLSVRL---------------EFDYSEDKSSWDNQQENPPPTKKIGKKP 371
            +E+       +G+S+ +               E++  E+   +  +++    +K++  +P
Sbjct: 9492 EEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEP 9551

Query: 372  VAKMPLRRPKM---KKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPF 428
                  +  K+    K P K++  P  P + P  P  I   K        K   P     
Sbjct: 9552 AEVTERQEKKIVLKPKIPAKIEEPP--PAKVPEAPKKIVPEKKVPAPVPKKEKVP----- 9604

Query: 429  SSTSKMQESPKLPQQSYNFDPDTCD-ESVDPFKTSSK-----------TPSSPSKSPASF 476
                K+ E PK P       P     E   P K + +              +  ++P   
Sbjct: 9605 --PPKVPEEPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKA 9662

Query: 477  EIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPET 536
             +P     A   +     KP ++++ P K   FR +   +     + P ++P P      
Sbjct: 9663 RVPEEPKRAVPEEKVLKLKPKREEEPPAKVTEFRKRVVKEEKVSIEAPKREPQPIKE--- 9719

Query: 537  PPVISAVVHATDEEKLAVTNQKWTCMTVDLEADKQDYPQPSDLSTFVNETKFSSPTEELD 596
                   V   +E++ A T ++   ++V  E + ++Y +         E +   PTEE D
Sbjct: 9720 -------VTIMEEKERAYTLEE-EAVSVQREEEYEEYEEYD-----YKEFEEYEPTEEYD 9766

Query: 597  YRNSYEIEYMEKIGSSLPQDDDAPKKQALYLMFDTSQESPVKSSPVRMSESPTPCSGSSF 656
                YE    E+            ++   Y+   T  E P+   PV     PT       
Sbjct: 9767 QYEEYEEREYERY-----------EEHEEYI---TEPEKPIPVKPVPEEPVPTKPKAPPA 9812

Query: 657  EETEALVNTAAKNQHPVPRGLAPNQESHLQVPEKSSQKELEAMGLGTPSEAIEITAP 713
            +  +  V    K   P+P+ L P      + P+K  ++++      T  E  ++T P
Sbjct: 9813 KVLKKAV-PEEKVPVPIPKKLKPPPPKVPEEPKKVFEEKIRIS--ITKREKEQVTEP 9866



 Score = 47.4 bits (111), Expect = 7e-05
 Identities = 88/397 (22%), Positives = 144/397 (36%), Gaps = 46/397 (11%)

Query: 21    EAMSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDG 80
             EA  +   E  + PE   PV  P    PPP +V   PEV  +P PEE       VPVP  
Sbjct: 9972  EAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKV---PEVPKKPVPEE----KVPVPVP-- 10022

Query: 81    PRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQ 140
                  VE  P + P      V ++  P+ +     ++    ++ +  + L P        
Sbjct: 10023 ---KKVEAPPAKVPEVPKKPVPEKKVPVPA--PKKVEAPPAKVPEVPKKLIPEEKKPTPV 10077

Query: 141   EGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASS 200
               KV         VP  +  +   ++L   +         PE   L  +           
Sbjct: 10078 PKKVEA---PPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEE---------EE 10125

Query: 201   TLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKT-ESAKTE 259
              L   ++  P   ++++   +  E PP  E ++ P EE  VP  E    E +     K +
Sbjct: 10126 VLPEEEEVLP---EEEEVLPEEEEIPP--EEEEVPPEEEYVPEEEEFVPEEEVLPEVKPK 10180

Query: 260   GPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSP---PVGRKTLPLTT 316
              P PA + E   +     K   P   E+    VP      +V+      P   + LP+  
Sbjct: 10181 VPVPAPVPEIK-KKVTEKKVVIPKKEEAPPAKVPEVP--KKVEEKRIILPKEEEVLPVEV 10237

Query: 317   APEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQ---ENPPPTKKIGKKPVA 373
               E  E   S    +E+ P +  S+    + +  +     ++   E P P  K  + P A
Sbjct: 10238 TEEPEEEPIS----EEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKKVEAPPA 10293

Query: 374   KMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAK 410
             K+  + P+ +K P  +    A P + P  P  +P  K
Sbjct: 10294 KVSKKIPE-EKVPVPVQKKEAPPAKVPEVPKKVPEKK 10329



 Score = 39.7 bits (91), Expect = 0.015
 Identities = 33/115 (28%), Positives = 46/115 (40%), Gaps = 14/115 (12%)

Query: 8     QPAPASDLNLEASEAMSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPE- 66
             +P P  ++ L++      + EE    P+    VK P  P PPPP+ + E EV T    E 
Sbjct: 10940 KPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRER 10999

Query: 67    ---EPGCGSE-----TVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGT 113
                EP    E      +P P+       E    +PP      V  E  PIA+  T
Sbjct: 11000 KIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPP-----PVEPEPTPIAAPVT 11049



 Score = 37.0 bits (84), Expect = 0.095
 Identities = 79/352 (22%), Positives = 112/352 (31%), Gaps = 86/352 (24%)

Query: 21    EAMSSDSEEAFETPESTTPVK--APPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVP 78
             E   S   E +E PE   P +  AP    P P     EPEV     PEEP    + +P  
Sbjct: 10794 ERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEP---KKIIPEK 10850

Query: 79    DGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAK 138
               P     E  P + P      V ++ K                       L+PR     
Sbjct: 10851 KVPVIKKPEAPPPKEPEP--EKVIEKPK-----------------------LKPRPPPPP 10885

Query: 139   NQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSA 198
                 K + + K      I K  +     +             PE V L P     G    
Sbjct: 10886 PAPPKEDVKEKIFQLKAIPKKKVPEKPQV-------------PEKVELTPLKVPGGEKKV 10932

Query: 199   SSTL-KRTKKPRPPSLKKKQTTKKPTETPPVKETQQ---------------EPDEESLVP 242
                L +R  +P+   + K    K+P E  P  E ++               +P EE  VP
Sbjct: 10933 RKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVP 10992

Query: 243   S----GENLASETKTESAKTEGPSPA------------LLEETPLEPAVGPKAA---CPL 283
             +       +   TK    K   P PA             ++  P+EP   P AA    P+
Sbjct: 10993 TVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPV 11052

Query: 284   DSESAEGVVP---PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQE 332
               + AE   P    A   G ++  P    K  P     E  ++ P  SGG++
Sbjct: 11053 VGKKAEAKAPKEEAAKPKGPIKGVP----KKTPSPIEAERRKLRPG-SGGEK 11099



 Score = 37.0 bits (84), Expect = 0.095
 Identities = 69/336 (20%), Positives = 116/336 (34%), Gaps = 48/336 (14%)

Query: 21    EAMSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVST-----QPPPEEPGCGSETV 75
             E ++ + E+     E   P   PPA P  P ++IPE +V        PPP+EP    E  
Sbjct: 10814 EEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEP----EPE 10869

Query: 76    PVPDGPR-SDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRA 134
              V + P+        P  PP         + K I          +  ++ +  +    + 
Sbjct: 10870 KVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVP----EKPQVPEKVELTPLKV 10925

Query: 135   SDAKNQEGKVNTRRK-STDSVPISKSTLSRSLSLQASDFDGAS-SSGNPEAVALAPDAYS 192
                + +  K+   RK       + KS L +    +    +          AV   P    
Sbjct: 10926 PGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKP 10985

Query: 193   TGSSSASSTLKRTKK-PRP-------PSLKKKQTTKKPTETPPVKETQQEPDEESLVPSG 244
                    +  KR +K P P       P++       KP     VK  +  P E    P  
Sbjct: 10986 VEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIA 11045

Query: 245   ENL----------ASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPP 294
               +          A   K E+AK +GP   + ++TP           P+++E  +  + P
Sbjct: 11046 APVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTP----------SPIEAERRK--LRP 11093

Query: 295   ASGGGRVQNSPP--VGRKTLPLTTAPEAGEVTPSDS 328
              SGG +  +  P     K +PL    E  ++  ++S
Sbjct: 11094 GSGGEKPPDEAPFTYQLKAVPLKFVKEIKDIILTES 11129



 Score = 31.6 bits (70), Expect = 4.0
 Identities = 38/193 (19%), Positives = 84/193 (43%), Gaps = 16/193 (8%)

Query: 824  DLDSALQIARAEIITKEREVSEWKDK-YEESRREVMEMRKIVAEYEKTIAQMIEDEQREK 882
            D+ S  +  +   IT+++EV + K+  YE+ +    E R  +  +E+       DE   +
Sbjct: 9029 DVSSKAEEVKIMTITRKKEVQKEKEAVYEKKQAVHKEKRVFIESFEEPY-----DELEVE 9083

Query: 883  SVSHQTVQQLVLEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYL 942
              +    Q    E ++   ++    K         E  +E  E F + +E  +R  + Y 
Sbjct: 9084 PYTEPFEQPYYEEPDEDYEEIKVEAKK--------EVHEEWEEDFEEGQEYYER-EEGYD 9134

Query: 943  SRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQEQAAHQASLRKEQLRVDALERTL 1002
               ++ E+ YQ  +V   +K     +   +V  K  +++A     + K+ + ++ +E+T 
Sbjct: 9135 EGEEEWEEAYQEREVIQVQKEVYEESHERKVPAKVPEKKAPPPPKVIKKPV-IEKIEKTS 9193

Query: 1003 EQKNKEIEELTKI 1015
             +  +E  ++TK+
Sbjct: 9194 RRMEEEKVQVTKV 9206



 Score = 31.2 bits (69), Expect = 5.2
 Identities = 22/79 (27%), Positives = 35/79 (44%)

Query: 613   LPQDDDAPKKQALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHP 672
             LP  ++  ++  L    DTS +    S  V+MS S    S SSF  + A   T  K    
Sbjct: 33224 LPLVEEPSREVVLRTSGDTSLQGSFSSQSVQMSASKQEASFSSFSSSSASSMTEMKFASM 33283

Query: 673   VPRGLAPNQESHLQVPEKS 691
               + ++  QES +++   S
Sbjct: 33284 SAQSMSSMQESFVEMSSSS 33302



 Score = 30.4 bits (67), Expect = 8.9
 Identities = 51/247 (20%), Positives = 90/247 (36%), Gaps = 30/247 (12%)

Query: 39  PVKAPPAPP-------PPPPEVIPEPEVSTQPPPEEPGCGSETV-----PVPDGPRSDS- 85
           P K PP  P       P PP +  + +++ Q  P         V     P P   RS S 
Sbjct: 250 PHKTPPRIPPKPKSRSPTPPSIAAKAQLARQQSPSPIRHSPSPVRHVRAPTPSPVRSVSP 309

Query: 86  ---VEGSP---------FRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPR 133
              +  SP          R    S  A   E  P      Y       E+ +T  T   +
Sbjct: 310 AARISTSPIRSVRSPLLMRKTQASTVATGPEVPPPWKQEGYVASSSEAEMRETTLTTSTQ 369

Query: 134 ASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYST 193
               +  EG+   + + T S     +  + S+S  AS    A ++G  E    A  + + 
Sbjct: 370 IRTEERWEGRYGVQEQVTIS---GAAGAAASVSASASYAAEAVATGAKEVKQDADKSAAV 426

Query: 194 GSSSASSTLKRTKKPRPPSLKK--KQTTKKPTETPPVKETQQEPDEESLVPSGENLASET 251
            +  A+  + R ++P   ++++  ++TT       P +E  ++  E++ V      A + 
Sbjct: 427 ATVVAAVDMARVREPVISAVEQTAQRTTTTAVHIQPAQEQVRKEAEKTAVTKVVVAADKA 486

Query: 252 KTESAKT 258
           K +  K+
Sbjct: 487 KEQELKS 493


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 70.5 bits (171), Expect = 8e-12
 Identities = 142/607 (23%), Positives = 204/607 (33%), Gaps = 90/607 (14%)

Query: 3   GSQSLQPAPASDLNLEASEAMSSDSEEAFETP--------------ESTTPVKA--PPAP 46
           G Q+L+P   +    +A+ A+   S     TP               + TP+ A  PP+P
Sbjct: 276 GLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSP 335

Query: 47  P--------PPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSF 98
           P        PP P   P  +    PP   P     ++  P      S++  P     HS 
Sbjct: 336 PLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSL 395

Query: 99  S--AVFDEDKPIASS---GTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKST-- 151
           +  ++     P+A S    T +L    ++   +F T+ PR + A        +R  ST  
Sbjct: 396 TSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTS---PSRPASTPP 452

Query: 152 DSVPI-SKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP-- 208
           DS P+ +  +L  S  LQ S     S   +P  +       S  S S  + L     P  
Sbjct: 453 DSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPL 512

Query: 209 ------RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPS 262
                  PPSL   QT      TPP++         SL P     AS   T       P 
Sbjct: 513 ETQSSLAPPSL---QTPPASLTTPPLENL------PSLAPPPLQTASAPLTTPHLETPPC 563

Query: 263 PALLE-ETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQN--SPPVG----------- 308
           PA    + P  P   P    P    +     PPA     +Q   SPP+            
Sbjct: 564 PAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPP 623

Query: 309 RKTLPLTTAPEAGEVTPSDSGGQEDSP--AKGLSVR-LEFDYSEDKSSWDNQQENPPPTK 365
              LP   AP +   +P  S     SP     L+V  L+  +S   S       +PP + 
Sbjct: 624 XLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP 683

Query: 366 KIGKKPVAKMPLRRPKMKKTP--EKLDNTPASPPRSP-------------AEPNDIPIA- 409
            +   P A  P + P     P  +   + PASPP SP             A P  +P + 
Sbjct: 684 PV--SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSP 741

Query: 410 KGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSP 469
             +          P   P  +   +Q  P  P  S    P        P   ++    + 
Sbjct: 742 PASPPMSPSATPPPRVPPLLAAPPLQVPPS-PPASLPMSPLAKPPPQAPPALATPPLQAL 800

Query: 470 SKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPT 529
              PASF   A    +  +    L  P  +    L     +V  SP  SP    P + PT
Sbjct: 801 PSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPT 860

Query: 530 PAATPET 536
           P   P+T
Sbjct: 861 PG--PDT 865



 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 134/561 (23%), Positives = 185/561 (32%), Gaps = 67/561 (11%)

Query: 20  SEAMSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPD 79
           S AM+  S  A    E   P  AP A P PP E    P  S     E     S T P P 
Sbjct: 173 SPAMARRSRAA--GTEVGLPRPAPSARPRPPTE---GPRKSVSSASEH----STTEPSPA 223

Query: 80  GPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDN------------IELVDTF 127
             R  S  G   RP S S S+        A SG                    ++ +   
Sbjct: 224 ARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPP 283

Query: 128 QTLEPRASDAKNQEGKVNTRRKSTDSVPISKS---------------TLSRSLSLQASDF 172
           Q   PR  DA    G +++   +T S   +K+               TL  S  L     
Sbjct: 284 QVTPPR-KDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLP 342

Query: 173 DGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTE-TPPVKET 231
               S   P ++   P   +T  S A  ++       PPSL+     + P   T P  + 
Sbjct: 343 LAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQA 402

Query: 232 QQEPDEESLVPSGENLASET--KTESAKTEGPSPALLEET-PLEPAVGPKAACPLDSESA 288
              P   S + +  +L S T   T S  T  P       T P  PA  P  + PL +  +
Sbjct: 403 PPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLS 462

Query: 289 EGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYS 348
               PP     +   SP V   + PLT  P       + S     SP   LS  +     
Sbjct: 463 LPASPPL----QTSLSPAVSPLSSPLTIHP-----LQALSSLASHSPQAPLSSLIMPPLE 513

Query: 349 EDKSSWDNQQENPPP---TKKIGKKP-VAKMPLRRPKMKKTPEKLDNTPASPP---RSPA 401
              S      + PP    T  +   P +A  PL+      T   L+  P   P   ++P 
Sbjct: 514 TQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPP 573

Query: 402 EPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDE--SVDPF 459
            P   P  +   +        P   P  ++  +Q  P  P       P       ++ P 
Sbjct: 574 SPLTTPPPETPSSIATPP---PQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPL 630

Query: 460 KTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSP 519
           +     P+SP  SP +   P +    N +    L  P     +P     F    SP  SP
Sbjct: 631 QAPPSPPASPPLSPLATPSPQAP---NALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSP 687

Query: 520 LSDPPSQDPTPAATP--ETPP 538
            + PPSQ P   A P  + PP
Sbjct: 688 SATPPSQAPPSLAAPPLQVPP 708



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 127/592 (21%), Positives = 186/592 (31%), Gaps = 96/592 (16%)

Query: 30  AFETPESTTP---VKAPPAPPPPPPEVIPEP--------EVSTQPPPEEP-GCGSETVPV 77
           A  TP +  P      PP  P PPP V P           V  +P  E   G G  T+P 
Sbjct: 13  AARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPE 72

Query: 78  ------PDGPRSDSVEGSPFRPPS-----HSFSAVFDEDKPIASSGTYN-------LDFD 119
                 P      S      RPP+      +  A      P++S G  +       L   
Sbjct: 73  SAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQK 132

Query: 120 NIELVDTFQTLEPRASDA-KNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDG---A 175
            + +         +A++A K        RR ++   P + S      S  A    G    
Sbjct: 133 GLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRP 192

Query: 176 SSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPS----LKKKQTTKKPTETPPVKET 231
           + S  P      P    + +S  S+T       R PS    L++  +    +   P+   
Sbjct: 193 APSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSP 252

Query: 232 QQEPDEESLVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGV 291
            +        P      S+ K +  +   P           PA+GP ++ PL + S  G 
Sbjct: 253 ARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGT 312

Query: 292 ----VPPASGG-----GRVQNSPPVGRKTLPLT-----------TAPEAGEVTPSDSGGQ 331
               VPP           +  SPP+    LPL            T P      PS +   
Sbjct: 313 KARPVPPPDNAATPLPATLPPSPPLA-TPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPS 371

Query: 332 EDSPAKGLSVRLE-FDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLD 390
             +P       L+     +   S  +     PP+        A   L  P ++ T   L 
Sbjct: 372 MTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLT 431

Query: 391 NTP-------ASPPRSPAEPNDIPIAKGTYTF----DIDKWDDPNFNPFSS--------- 430
            +P        SP R  + P D P  +   +      +     P  +P SS         
Sbjct: 432 MSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQA 491

Query: 431 -TSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVD 489
            +S    SP+ P  S    P     S+ P   S +TP +   +P    +P+ A       
Sbjct: 492 LSSLASHSPQAPLSSLIMPPLETQSSLAP--PSLQTPPASLTTPPLENLPSLA------- 542

Query: 490 GDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVIS 541
                 P +    PL T        P   PL  PPS   TP   PETP  I+
Sbjct: 543 ----PPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTP--PPETPSSIA 588



 Score = 39.3 bits (90), Expect = 0.019
 Identities = 73/307 (23%), Positives = 105/307 (34%), Gaps = 48/307 (15%)

Query: 4    SQSLQPAPASDLNLEASEAMSSDSEEAFE--TPESTTPVKAPP---APP----PPPPEVI 54
            S S  P P +   L A       S  A    +P +T P + PP   APP    P PP  +
Sbjct: 717  SPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASL 776

Query: 55   PEPEVSTQPPPEEPGCGSETVPVPDGPRSDSVEGSPFRP----PSHSFSAVFDEDKPIAS 110
            P   ++  PP   P   +  +     P +     +PF P    P    +    +  P+ +
Sbjct: 777  PMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLA 836

Query: 111  SGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLS--LQ 168
            +    +   +     T Q   PR       +  V+  R +    P      SRS S  L 
Sbjct: 837  APLLQVP-PSPPASPTLQA--PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLS 893

Query: 169  ASDFDGASSSGN------------PEAVALA---PDAYSTGSSSASSTLKRTKKPRPPSL 213
              D  G SSS              PE  A A   PDA       A+ +    + P PP L
Sbjct: 894  GPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWS----RGPAPP-L 948

Query: 214  KKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEETPLEP 273
              +     P   PP               S + L +  +TE  ++  P+P  L+  P   
Sbjct: 949  AFRGAPGAPLPWPPATGPG----------SADGLCTIYETEGPESATPAPGALDPGPSPG 998

Query: 274  AVGPKAA 280
              G KAA
Sbjct: 999  TSGGKAA 1005


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 67.8 bits (164), Expect = 5e-11
 Identities = 124/587 (21%), Positives = 207/587 (35%), Gaps = 98/587 (16%)

Query: 2    GGSQSLQPAPASDLNLEASEAMSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVST 61
            GG +  +  PA +      EA S   EEA    +S    K+P       P  +  PE + 
Sbjct: 496  GGEEETKSPPAEEAASPEKEAKSPVKEEA----KSPAEAKSPEKEEAKSPAEVKSPEKAK 551

Query: 62   QPPPEEPGCGSETVPVPDGPRSDSVEG-SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDN 120
             P  EE    +++ P    P  +  +  +  + P  + S   +E K  A           
Sbjct: 552  SPAKEE----AKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPA----------- 596

Query: 121  IELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGN 180
                           +AK+ E   +  ++   S   +KS +                   
Sbjct: 597  ---------------EAKSPEKAKSPVKEEAKSPAEAKSPVKEE---------------- 625

Query: 181  PEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTET-PPVKETQQEPDEES 239
                A +P    +   + S T +  K P      +K+  K P +   PVK   + P++  
Sbjct: 626  ----AKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAK 681

Query: 240  LVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGG 299
                 E  + E      K E  SP   +    E A  P+ A     E A+      S   
Sbjct: 682  SPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVK 741

Query: 300  RVQNSP-----PVGRKTLPLTTAPEAGEVTPSDSGGQEDS-PAKGLSVRLEFDYSEDKSS 353
                SP     P   KTL +  +PEA      ++    D  P K  S   E   S +K+ 
Sbjct: 742  EEAKSPEKAKSPEKAKTLDV-KSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAK 800

Query: 354  WDNQQENPPPTKKIGKKPVAKMPLRRP------KMKKTPEKLDNTPASPPRSPAEPNDIP 407
               +++   P K+I KK   K P++        K+K+ P+K     A   ++PA P    
Sbjct: 801  SPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKK-----AEEEKAPATP---- 851

Query: 408  IAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPS 467
              K     D  K + P         + ++ P + +   +      +E+ D      K P+
Sbjct: 852  --KTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAED----KKKVPT 905

Query: 468  SPSKSPASFEIPASA----------MEANGVDGDGLNKPAKKKK-TPLKTDTFRVK-KSP 515
               ++PA  E+   A           E +       +KPA+KK+  P K DT   K K P
Sbjct: 906  PEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKP 965

Query: 516  KRSPLSDPPSQ--DPTPAATPETPPVISAVVHATDEEKLAVTNQKWT 560
            +  P ++  ++  D T +  P  P    A   ++ ++K +   +K T
Sbjct: 966  EEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKAT 1012



 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 121/591 (20%), Positives = 221/591 (37%), Gaps = 67/591 (11%)

Query: 126  TFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVA 185
            T +  E    +AK +EGK     +  ++    + T S            A  + +PE  A
Sbjct: 467  TEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPP----------AEEAASPEKEA 516

Query: 186  LAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGE 245
             +P      S + + + ++ +   P  +K  +  K P +    +E +  P+ +S  P  E
Sbjct: 517  KSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAK----EEAKSPPEAKS--PEKE 570

Query: 246  NLASETKTESAKTEGPSPALLE-ETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNS 304
               S  + +S + +  SPA  E ++P E     KA  P+  E+      PA     V+  
Sbjct: 571  EAKSPAEVKSPE-KAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKS----PAEAKSPVKEE 625

Query: 305  PPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPT 364
                 K+     +PE  +   S +  +  SP K  S   E   S +K+    + E   P 
Sbjct: 626  A----KSPAEVKSPEKAK---SPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPE 678

Query: 365  KKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPA-EPNDIPIAKGTYTFDIDKWDDP 423
            K   K PV K   + P+  K+P K +       +SP  E    P    +   +  K  + 
Sbjct: 679  K--AKSPV-KAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEK 735

Query: 424  NFNPFSSTSKMQESPKLPQQSYNFD----------PDTCDESVDPFKTSSKTP-----SS 468
              +P    +K  E  K P+++   D           +      D F   +K+P      S
Sbjct: 736  AKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKS 795

Query: 469  PSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRS----PLSDPP 524
            P K+ +  +  A A E      + +  P K+++ P +    +VK+ PK++      + P 
Sbjct: 796  PEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEV---KVKEPPKKAEEEKAPATPK 852

Query: 525  SQDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTVDLE--ADKQDYPQPSDLSTF 582
            +++   +   E P   +      ++++ AV   K + +    E   DK+  P P   +  
Sbjct: 853  TEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPA 912

Query: 583  VNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQALYLMFDTSQESPVKSSPV 642
              E K  +  +E       E +  +    S P    A KK+A     DT +E   K    
Sbjct: 913  KVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKP----AEKKEAAPEKKDTKEEKAKK---- 964

Query: 643  RMSESPTPCSGSSFEETEALVNTAAKNQHPVPRGLAPNQESHLQVPEKSSQ 693
               E        + E+ + L    +K +       +   +   + PEK+++
Sbjct: 965  --PEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATE 1013



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 102/498 (20%), Positives = 194/498 (38%), Gaps = 59/498 (11%)

Query: 528  PTPAATPETPPVISAV---VHATDEEKLAVTNQKWTCMTVDLEADKQDYPQPSDLSTFVN 584
            P P + PE  P I +V   +    EEK+ V  +K    TV +E   ++     +++    
Sbjct: 417  PIPFSLPEGLPKIPSVSTHIKVKSEEKIKVV-EKSEKETVIVEEQTEETQVTEEVTEEEE 475

Query: 585  ETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDA-PKKQALYLMFDTSQESPVKSSPVR 643
            +       +E +     E E  E+   S P ++ A P+K+A         +SPVK     
Sbjct: 476  KEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEA---------KSPVKE---- 522

Query: 644  MSESPTPCSGSSFEETEALVNTAAKNQHPVPRGLAPNQESHLQVPEKSSQKELEAMGLGT 703
              E+ +P    S E+ EA      K+     +  +P +E     PE  S ++ EA     
Sbjct: 523  --EAKSPAEAKSPEKEEAKSPAEVKSPE---KAKSPAKEEAKSPPEAKSPEKEEA----- 572

Query: 704  PSEAIEITAPEGSFASADALLSRLAHPVSLCGALDYLEPDLAEKNPPLFAQKLQEELEFA 763
                 E+ +PE + + A         P           P   E   P  A+   +E   +
Sbjct: 573  -KSPAEVKSPEKAKSPAK---EEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKS 628

Query: 764  IMRIEALKLAR-----QIALASRSHQDAKREAAHPTDVSISKTALYSRIGTAEVEK-PAG 817
               +++ + A+     +     ++    K EA  P     +K+ + +   + E  K P  
Sbjct: 629  PAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEK---AKSPVKAEAKSPEKAKSPVK 685

Query: 818  LLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIED 877
               + P+   A    + E  + E+  S  K++ +   +    +++     EK  + + E+
Sbjct: 686  AEAKSPE--KAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEE 743

Query: 878  EQR-EKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKR 936
             +  EK+ S +  + L ++  +A        +S AD F   EK K  ++   K+ E  K 
Sbjct: 744  AKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFP--EKAKSPVKEEVKSPEKAKS 801

Query: 937  CAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQEQAAHQASLRKEQLRVD 996
              +E     +KE  + + +K   +E+      ++ +   KA++E+A              
Sbjct: 802  PLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKA-------------P 848

Query: 997  ALERTLEQKNKEIEELTK 1014
            A  +T E+K+ + EE  K
Sbjct: 849  ATPKTEEKKDSKKEEAPK 866



 Score = 32.0 bits (71), Expect = 3.1
 Identities = 58/274 (21%), Positives = 96/274 (35%), Gaps = 59/274 (21%)

Query: 9    PAPASDLNLEASEAMSSDSEEAFETPESTTP----------VKAPPAPPPP-------PP 51
            P  A  L++++ EA +   EEA  +P    P          VK+P     P       P 
Sbjct: 753  PEKAKTLDVKSPEAKTPAKEEA-RSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPE 811

Query: 52   EVIPEPEVSTQPPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASS 111
            + IP+ E    P  EE     + V V + P+    E +P  P +        E+ P   +
Sbjct: 812  KEIPKKEEVKSPVKEEEK--PQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEA 869

Query: 112  GTYNLDFDNIELVDTFQTLEPRAS--DAKNQEG----KVNTRRKST--------DSVPIS 157
                ++      V+     +P+ S  +AK +E     KV T  K          D+ P  
Sbjct: 870  PKPKVEEKKEPAVE-----KPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKE 924

Query: 158  KSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTK----------- 206
            K+ +++    +  D      S   E    AP+   T    A    ++ K           
Sbjct: 925  KTEVAKK---EPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKT 981

Query: 207  ------KPRPPSLKKKQTTKKPTETPPVKETQQE 234
                  KP+    +K  +T +    PP K T+ +
Sbjct: 982  LSKEPSKPKAEKAEKSSSTDQKDSKPPEKATEDK 1015


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 67.4 bits (163), Expect = 7e-11
 Identities = 164/743 (22%), Positives = 253/743 (34%), Gaps = 124/743 (16%)

Query: 4    SQSLQPAPASDLNLEASEAMSSDSEEAF-------ETPESTTPVKAPPAPPPPPPEVIPE 56
            S +  P  AS L+    E  +S   EA        E+P S  P ++P +PPP      P 
Sbjct: 456  SPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPL 515

Query: 57   PEVSTQPPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNL 116
             E    PP E P       P  + P S   E SP  PP         E+ P++       
Sbjct: 516  EESPLSPPEESP-----PSPALETPLSPPPEASPLSPPF--------EESPLSPPPE--- 559

Query: 117  DFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGAS 176
                 EL  +      R S    +        +S  S P   S L          F+ + 
Sbjct: 560  -----ELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRL-------FPPFEESP 607

Query: 177  SSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPD 236
             S  PE   L+P   ++  S        +  P    +       + +  P V      P+
Sbjct: 608  LSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPE 667

Query: 237  EESLVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPAS 296
            E  L P  E   +    E+++   P     E++P  P      A P   +S   +    S
Sbjct: 668  ESPLSPPPEESPTSPPPEASRLSPPP----EDSPTSPPPEDSPASPPPEDSLMSLPLEES 723

Query: 297  GGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSP---AKGLSVRLEFDYSEDKSS 353
                            PL   PE  ++ P  S G   SP      LS R E  +   ++ 
Sbjct: 724  ----------------PLLPLPEEPQLCPR-SEGPHLSPRPEEPHLSPRPEEPHLSPQAE 766

Query: 354  WDNQQENP--PPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKG 411
              +    P  P    + ++P        P +   PE+L  +P +      EP+  P+   
Sbjct: 767  EPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQT-----EEPHLSPVP-- 819

Query: 412  TYTFDIDKWDDPNFNP---FSSTSKMQESPKL---PQQSYNFDPDTCDESVDPFKTSSKT 465
                     ++P  +P    S  S   E P L   P++S+   P+     + P     K 
Sbjct: 820  ---------EEPCLSPQPEESHLSPQSEEPCLSPRPEESH-LSPELEKPPLSP--RPEKP 867

Query: 466  PSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKK--KTPLKTDTFRVKKSPKRSPLSDP 523
            P  P + PA  E+P             L +PA  +  + PL      +  SP   P   P
Sbjct: 868  PEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSP 927

Query: 524  PSQDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTVDLE---ADKQDYPQPSDLS 580
                P P      PP +S ++ A     L+           +LE     K D    S L+
Sbjct: 928  QLMPPDP-----LPPPLSPIITAAAPPALSPLG--------ELEYPFGAKGDSDPESPLA 974

Query: 581  TFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQALYLMFD--TSQESP-V 637
              + ET  S P E     N  + E +  +   LP    +P   A  ++ +    Q SP +
Sbjct: 975  APILETPISPPPE----ANCTDPEPVPPM--ILPPSPGSPVGPASPILMEPLPPQCSPLL 1028

Query: 638  KSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHPVPR--GLAPNQESHLQVPEKSSQKE 695
            + S V  +  P+ CS        AL  +      P+ +  G++   E H    EK S+ E
Sbjct: 1029 QHSLVPQNSPPSQCS------PPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPE 1082

Query: 696  LEAMGLGTPSEAIEITAPEGSFA 718
              A+    PS    + +P G  +
Sbjct: 1083 CPAL---EPSATSPLPSPMGDLS 1102



 Score = 36.6 bits (83), Expect = 0.12
 Identities = 74/334 (22%), Positives = 115/334 (34%), Gaps = 52/334 (15%)

Query: 437 SPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKP 496
           SP  P  +   +PD    +           S   K P   +  A  +   GV  +   + 
Sbjct: 373 SPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEA 432

Query: 497 AKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTN 556
              ++ PL          P+ SPLS PP + PT      +PP  ++ +    EE  A   
Sbjct: 433 PLNEEMPLLPP-------PEESPLSPPPEESPT------SPPPEASRLSPPPEELPA--- 476

Query: 557 QKWTCMTVDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSS-LPQ 615
                            P+   LS  + E+  S P EE       E      +  S L  
Sbjct: 477 --------------SPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSP 522

Query: 616 DDDAPKKQALYL----------MFDTSQESPVKSSPVRMSESPTPCSGSSFEETEALVNT 665
            +++P   AL            +    +ESP+   P  +  SP P +       E    +
Sbjct: 523 PEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMS 582

Query: 666 AAKNQHPV------PRGLAPNQESHLQVPEKSS--QKELEAMGLGTPSEAIEIT-APEGS 716
               + P+       R   P +ES L  P + S      EA  L  P E   ++  PE S
Sbjct: 583 PPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEES 642

Query: 717 FASADALLSRLAHPVSLCGALDYLEPDLAEKNPP 750
             S    +SRL+ P+ +   L    P+ +  +PP
Sbjct: 643 PMSPPPEVSRLS-PLPVVSRLS-PPPEESPLSPP 674



 Score = 33.5 bits (75), Expect = 1.1
 Identities = 72/312 (23%), Positives = 95/312 (30%), Gaps = 50/312 (16%)

Query: 10   APASDLNLEASEAMSSDSEEAFETPESTTPVKAPPA-----PPPPPPEVIPEPEVSTQPP 64
            +P  +L         SD E     P   TP+  PP      P P PP ++P    S   P
Sbjct: 952  SPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGP 1011

Query: 65   -------PEEPGCG----SETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGT 113
                   P  P C        VP    P   S    P   PS           P++  G 
Sbjct: 1012 ASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPS-----------PLSPIGK 1060

Query: 114  YNLDFDNIEL--VDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASD 171
                 D  EL  ++T +  EP     +           +T  +P     LS      A  
Sbjct: 1061 VVGVSDEAELHEMETEKVSEPECPALE---------PSATSPLPSPMGDLSCPAPSPAPA 1111

Query: 172  FDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKET 231
             D  S  G   A     DA   GS        +T       LK       P E  PV  T
Sbjct: 1112 LDDFSGLGEDTAPLDGIDA--PGSQPEPG---QTPGSLASELKGSPVLLDPEELAPV--T 1164

Query: 232  QQEPDEESLVPSGENLASETKTESAKTEGPSPALLEETPLEPAV-----GPKAACPLDSE 286
              E   E    +G+    E + E      P+P  L ++ +   +     G  +A    SE
Sbjct: 1165 PMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPPTLIKSDIVNEISNLSQGDASASFPGSE 1224

Query: 287  SAEGVVPPASGG 298
               G   P  GG
Sbjct: 1225 PLLGSPDPEGGG 1236



 Score = 32.3 bits (72), Expect = 2.4
 Identities = 22/69 (31%), Positives = 28/69 (40%), Gaps = 10/69 (14%)

Query: 34   PESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRS--------DS 85
            PE  +P  +P AP P  P   P  E+ T+P  E P      +P+   P S          
Sbjct: 4911 PEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPP--VPSPLPLASSPESARPKPRARPP 4968

Query: 86   VEGSPFRPP 94
             EG   RPP
Sbjct: 4969 EEGEDSRPP 4977



 Score = 31.6 bits (70), Expect = 4.0
 Identities = 79/314 (25%), Positives = 107/314 (34%), Gaps = 83/314 (26%)

Query: 10   APASDLNLEASEAMSSDSEEAFETPESTTPVKAPPAPPP-PPPEVIPEPEVSTQPPPEEP 68
            APA    L AS    +     F T    TP   P  P P   P     P +     PE P
Sbjct: 2205 APAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRC---PSLDNLAVPESP 2261

Query: 69   GCG----SETV--PVPDGPRSDSVE--------GSP-FRPPSHSFSAVFDEDKPIASSGT 113
            G G    SE +  P P G    ++E         SP + PP+  F      D P  SSGT
Sbjct: 2262 GVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGF-----VDSP--SSGT 2314

Query: 114  YNLDFDNIELVDTFQT-LEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDF 172
            + L    ++  D F+  L PRAS  + Q                     S  L L+  + 
Sbjct: 2315 H-LGGLELKTPDVFKAPLTPRASQVEPQ---------------------SPGLGLRPQE- 2351

Query: 173  DGASSSGNPEAVALA------PDAYSTGS-SSASSTLKRTKKPRPP------SLKKKQTT 219
                    P A ALA      PD +  GS +   +    T +P+PP      +L  +   
Sbjct: 2352 -------PPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLP 2404

Query: 220  KKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKA 279
              P    P     Q   +  L P         +  SA+   PSP     TP   +  P +
Sbjct: 2405 SDPFSRVPASPQSQSSSQSPLTP---------RPLSAEAFCPSPV----TPRFQSPDPYS 2451

Query: 280  ACPLDSESAEGVVP 293
              P   +S +   P
Sbjct: 2452 RPPSRPQSRDPFAP 2465



 Score = 30.8 bits (68), Expect = 6.8
 Identities = 29/122 (23%), Positives = 40/122 (32%), Gaps = 1/122 (0%)

Query: 208  PRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPS-GENLASETKTESAKTEGPSPALL 266
            P PP          P    P   + QEP   S +PS    L +E +        P P   
Sbjct: 4290 PAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGP 4349

Query: 267  EETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPS 326
               P    V P AA   D+  ++G+ P        +   P     +P       G+V P 
Sbjct: 4350 TLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSLVPGHLDQVNGQVVPE 4409

Query: 327  DS 328
             S
Sbjct: 4410 AS 4411



 Score = 30.8 bits (68), Expect = 6.8
 Identities = 87/392 (22%), Positives = 139/392 (35%), Gaps = 90/392 (22%)

Query: 36   STTPVKAPPAPPPPPPEVIPEPE-------------VSTQPPPEEPGCGSETVPVPDGPR 82
            ST PV  P   P PPP    EP+                Q PP  PG      P P GP 
Sbjct: 4297 STGPVLGP-VHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPG-----TPKPQGPT 4350

Query: 83   SDSVEG------------------SPFRPPSHSFSAVFDEDKPIASS-GTYNLDFDNIEL 123
             +   G                   P+ PP +    + +  KP  SS    +LD  N ++
Sbjct: 4351 LEPPPGRVSPAAAQLADTLFSKGLGPWDPPDN----LAETQKPEQSSLVPGHLDQVNGQV 4406

Query: 124  VDTFQTL--------EPRASDAKNQEGKVN--------TRRKSTDSVPISKS-TLSRSLS 166
            V     L        EP A  A++ + + N        T      + P S++  L     
Sbjct: 4407 VPEASQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHLLLAGPRSEAGHLLLQKL 4466

Query: 167  LQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETP 226
            L+A +   ++  G+    A       +  +     L+ T   +  +  +K  T KP    
Sbjct: 4467 LRAKNVQLSTGRGSEGLRAEINGHIDSKLAGLEQKLQGTPSNKEDAAARKPLTPKPKRVQ 4526

Query: 227  PVKE----TQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACP 282
               +    ++++  +E  V + E L  + K E +      PA+     L    G  + CP
Sbjct: 4527 KASDRLVSSRKKLRKEDGVRASEALLKQLKQELSLLPLTEPAITANFSLFAPFG--SGCP 4584

Query: 283  LDSESAEGVVPPASGGGRVQ---------------NSPPVGRKTLPLTTAPEAGE----- 322
            ++ +S    +  A G G +                ++PP    +LP T  P   +     
Sbjct: 4585 VNGQSQ---LRGAFGSGALPTGPDYYSQLLTKNNLSNPPTPPSSLPPTPPPSVQQKMVNG 4641

Query: 323  VTPSDSGGQ--EDSPAKGLSVRLEFDYSEDKS 352
            VTPS+  G+  +D+ +   S R   D SE KS
Sbjct: 4642 VTPSEELGEHPKDAASARDSERALRDTSEVKS 4673


>gi|16554449 zonadhesin isoform 3 [Homo sapiens]
          Length = 2812

 Score = 67.4 bits (163), Expect = 7e-11
 Identities = 104/446 (23%), Positives = 165/446 (36%), Gaps = 56/446 (12%)

Query: 181 PEAVALAPDAYSTGSSSASSTLKR----TKKPRPPSLKKKQTTKKPT---ETPPV----- 228
           PE   ++P + STG S  +   +     TKKP     K   TT+KPT   E P +     
Sbjct: 540 PELPPVSPVS-STGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKP 598

Query: 229 ----------KETQQEPDEESLVPSGEN--LASETKTESAKTEGPS--PALLEETPLEPA 274
                      E    P E+  +PS +   L  +    S K   PS  P +  E P  P 
Sbjct: 599 TISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPT 658

Query: 275 VGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDS 334
             P       + S E  V P       + S P  + ++P      + E T   +     S
Sbjct: 659 EEPTTPTEETTTSMEEPVIPTE-----KPSIPTEKPSIPTEKPTISMEETIISTEKPTIS 713

Query: 335 PAKGLSVRLEFDYSEDKSSWDNQQENPP---PTKKIGKKPVAKMPLRRPKMKKT--PEKL 389
           P K      +     +KS+   ++   P   PT    K  ++      P  K T  PEKL
Sbjct: 714 PEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKL 773

Query: 390 DNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDP 449
              P   P  P E   IP  K T +      ++P   P   T+   E P +P +      
Sbjct: 774 -TIPTEKPTIPTEKPTIPTEKPTIS-----TEEPT-TPTEETTISTEKPSIPMEKPTLPT 826

Query: 450 DTCDESVDPFKTSSKTPSSPSKSPA-SFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDT 508
           +    SV+    S++  + P + P  S E P    E   +  + L  P +K   P +  T
Sbjct: 827 EETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPT 886

Query: 509 FRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTVDLEA 568
             ++++   +     P++ PT   +PE P +          EK  +  +K T  T +   
Sbjct: 887 IPIEETTISTEKLTIPTEKPT--ISPEKPTI--------STEKPTIPTEKPTIPTEETTI 936

Query: 569 DKQDYPQPSDLSTFVNETKFSSPTEE 594
             +    P++  T ++  K + PTE+
Sbjct: 937 STEKLTIPTEKPT-ISPEKLTIPTEK 961



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 65/320 (20%), Positives = 117/320 (36%), Gaps = 40/320 (12%)

Query: 423 PNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPA-SFEIPAS 481
           P  +P SST   + +      + +    T   S++    +++ P+ P + P    E P  
Sbjct: 543 PPVSPVSSTGPSETTGLTENPTISTKKPTV--SIEKPSVTTEKPTVPKEKPTIPTEKPTI 600

Query: 482 AMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPT--------PAAT 533
           + E   +  +  N P++K   P +  T   +K    S     PS+ PT        P   
Sbjct: 601 STEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEE 660

Query: 534 PETP----------PVISAVVHATDEEKLAVTNQKWTCMTVD---------LEADKQDYP 574
           P TP          PVI     +   EK ++  +K T    +         +  +K   P
Sbjct: 661 PTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIP 720

Query: 575 Q-----PSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQALYLMF 629
                 P++ ST ++  K ++PTE+            EK  +   +   +P+K    L  
Sbjct: 721 TEKPTIPTEKST-ISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEK----LTI 775

Query: 630 DTSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHPVPRGLAPNQESHLQVPE 689
            T + +     P   +E PT  +      TE    +  K   P+ +   P +E+   V E
Sbjct: 776 PTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEE 835

Query: 690 KSSQKELEAMGLGTPSEAIE 709
            +   E   + +  P+ + E
Sbjct: 836 TTISTEKLTIPMEKPTISTE 855



 Score = 37.4 bits (85), Expect = 0.073
 Identities = 86/428 (20%), Positives = 144/428 (33%), Gaps = 80/428 (18%)

Query: 20  SEAMSSDSEE-AFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVP 78
           SE  +  SE+    T + T P + P  P       + EP +    P E+P   +E   +P
Sbjct: 637 SEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVI----PTEKPSIPTEKPSIP 692

Query: 79  DGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAK 138
               + S+E             +   +KP  S     +  +   +     T+ P      
Sbjct: 693 TEKPTISME-----------ETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTP 741

Query: 139 NQEGKVNTRRKSTD----SVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTG 194
            ++  + T + +      + P  K T+S                  PE + +  +  +  
Sbjct: 742 TEKPTIPTEKPTISPEKPTTPTEKPTIS------------------PEKLTIPTEKPTI- 782

Query: 195 SSSASSTLKRTKKPRPPSLKKKQTTKKPT----ETPPVKETQQEPDEESLVPSGENLAS- 249
                     T+KP  P+ K   +T++PT    ET    E    P E+  +P+ E   S 
Sbjct: 783 ---------PTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSV 833

Query: 250 -ETKTESAKTEGP--SPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPP 306
            ET   + K   P   P +  E P  P   P       + S E +  P       + + P
Sbjct: 834 EETTISTEKLTIPMEKPTISTEKPTIPTEKP-------TISPEKLTIPTE-----KLTIP 881

Query: 307 VGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKK 366
             + T+P+     + E     +     SP K          S +K +   ++   P  + 
Sbjct: 882 TEKPTIPIEETTISTEKLTIPTEKPTISPEKP-------TISTEKPTIPTEKPTIPTEET 934

Query: 367 IGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFN 426
                   +P  +P +  +PEKL   P   P    E   IP  K   T   +K   P   
Sbjct: 935 TISTEKLTIPTEKPTI--SPEKL-TIPTEKPTISTEKPTIPTEK--LTIPTEKPTIPTEK 989

Query: 427 PFSSTSKM 434
           P   T K+
Sbjct: 990 PTIPTEKL 997


>gi|27881494 zonadhesin isoform 6 [Homo sapiens]
          Length = 2721

 Score = 67.4 bits (163), Expect = 7e-11
 Identities = 104/446 (23%), Positives = 165/446 (36%), Gaps = 56/446 (12%)

Query: 181 PEAVALAPDAYSTGSSSASSTLKR----TKKPRPPSLKKKQTTKKPT---ETPPV----- 228
           PE   ++P + STG S  +   +     TKKP     K   TT+KPT   E P +     
Sbjct: 540 PELPPVSPVS-STGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKP 598

Query: 229 ----------KETQQEPDEESLVPSGEN--LASETKTESAKTEGPS--PALLEETPLEPA 274
                      E    P E+  +PS +   L  +    S K   PS  P +  E P  P 
Sbjct: 599 TISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPT 658

Query: 275 VGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDS 334
             P       + S E  V P       + S P  + ++P      + E T   +     S
Sbjct: 659 EEPTTPTEETTTSMEEPVIPTE-----KPSIPTEKPSIPTEKPTISMEETIISTEKPTIS 713

Query: 335 PAKGLSVRLEFDYSEDKSSWDNQQENPP---PTKKIGKKPVAKMPLRRPKMKKT--PEKL 389
           P K      +     +KS+   ++   P   PT    K  ++      P  K T  PEKL
Sbjct: 714 PEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKL 773

Query: 390 DNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDP 449
              P   P  P E   IP  K T +      ++P   P   T+   E P +P +      
Sbjct: 774 -TIPTEKPTIPTEKPTIPTEKPTIS-----TEEPT-TPTEETTISTEKPSIPMEKPTLPT 826

Query: 450 DTCDESVDPFKTSSKTPSSPSKSPA-SFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDT 508
           +    SV+    S++  + P + P  S E P    E   +  + L  P +K   P +  T
Sbjct: 827 EETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPT 886

Query: 509 FRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTVDLEA 568
             ++++   +     P++ PT   +PE P +          EK  +  +K T  T +   
Sbjct: 887 IPIEETTISTEKLTIPTEKPT--ISPEKPTI--------STEKPTIPTEKPTIPTEETTI 936

Query: 569 DKQDYPQPSDLSTFVNETKFSSPTEE 594
             +    P++  T ++  K + PTE+
Sbjct: 937 STEKLTIPTEKPT-ISPEKLTIPTEK 961



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 65/320 (20%), Positives = 117/320 (36%), Gaps = 40/320 (12%)

Query: 423 PNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPA-SFEIPAS 481
           P  +P SST   + +      + +    T   S++    +++ P+ P + P    E P  
Sbjct: 543 PPVSPVSSTGPSETTGLTENPTISTKKPTV--SIEKPSVTTEKPTVPKEKPTIPTEKPTI 600

Query: 482 AMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPT--------PAAT 533
           + E   +  +  N P++K   P +  T   +K    S     PS+ PT        P   
Sbjct: 601 STEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEE 660

Query: 534 PETP----------PVISAVVHATDEEKLAVTNQKWTCMTVD---------LEADKQDYP 574
           P TP          PVI     +   EK ++  +K T    +         +  +K   P
Sbjct: 661 PTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIP 720

Query: 575 Q-----PSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQALYLMF 629
                 P++ ST ++  K ++PTE+            EK  +   +   +P+K    L  
Sbjct: 721 TEKPTIPTEKST-ISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEK----LTI 775

Query: 630 DTSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHPVPRGLAPNQESHLQVPE 689
            T + +     P   +E PT  +      TE    +  K   P+ +   P +E+   V E
Sbjct: 776 PTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEE 835

Query: 690 KSSQKELEAMGLGTPSEAIE 709
            +   E   + +  P+ + E
Sbjct: 836 TTISTEKLTIPMEKPTISTE 855



 Score = 37.4 bits (85), Expect = 0.073
 Identities = 86/428 (20%), Positives = 144/428 (33%), Gaps = 80/428 (18%)

Query: 20  SEAMSSDSEE-AFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVP 78
           SE  +  SE+    T + T P + P  P       + EP +    P E+P   +E   +P
Sbjct: 637 SEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVI----PTEKPSIPTEKPSIP 692

Query: 79  DGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAK 138
               + S+E             +   +KP  S     +  +   +     T+ P      
Sbjct: 693 TEKPTISME-----------ETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTP 741

Query: 139 NQEGKVNTRRKSTD----SVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTG 194
            ++  + T + +      + P  K T+S                  PE + +  +  +  
Sbjct: 742 TEKPTIPTEKPTISPEKPTTPTEKPTIS------------------PEKLTIPTEKPTI- 782

Query: 195 SSSASSTLKRTKKPRPPSLKKKQTTKKPT----ETPPVKETQQEPDEESLVPSGENLAS- 249
                     T+KP  P+ K   +T++PT    ET    E    P E+  +P+ E   S 
Sbjct: 783 ---------PTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSV 833

Query: 250 -ETKTESAKTEGP--SPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPP 306
            ET   + K   P   P +  E P  P   P       + S E +  P       + + P
Sbjct: 834 EETTISTEKLTIPMEKPTISTEKPTIPTEKP-------TISPEKLTIPTE-----KLTIP 881

Query: 307 VGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKK 366
             + T+P+     + E     +     SP K          S +K +   ++   P  + 
Sbjct: 882 TEKPTIPIEETTISTEKLTIPTEKPTISPEKP-------TISTEKPTIPTEKPTIPTEET 934

Query: 367 IGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFN 426
                   +P  +P +  +PEKL   P   P    E   IP  K   T   +K   P   
Sbjct: 935 TISTEKLTIPTEKPTI--SPEKL-TIPTEKPTISTEKPTIPTEK--LTIPTEKPTIPTEK 989

Query: 427 PFSSTSKM 434
           P   T K+
Sbjct: 990 PTIPTEKL 997


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 63.9 bits (154), Expect = 7e-10
 Identities = 123/555 (22%), Positives = 195/555 (35%), Gaps = 81/555 (14%)

Query: 4   SQSLQPAPAS-DLNLEASEAMSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQ 62
           S+S  PAP   +   E  E      E + +   ST+ +   P P P P    P PE +++
Sbjct: 207 SRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSK 266

Query: 63  PPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIE 122
              E+     E        RS S   +  R PSH+        +P     + +  +    
Sbjct: 267 KEKEK-----EKTRPRSRSRSKSRSRTRSRSPSHT--------RPRRRHRSRSRSYSPRR 313

Query: 123 LVDTFQTLEPRASDA----------KNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDF 172
                +   PR              +     V  RR+S+ S+  S S+ S S S      
Sbjct: 314 RPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRS------ 367

Query: 173 DGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQ 232
              S    P     +P   +   S ++S  +R  +P PP+    +T   PT   P +  +
Sbjct: 368 --RSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPT---PQQSNR 422

Query: 233 QEPDEESLVPSGENLASETKTE-SAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGV 291
                 S+ P G      TK + + K E PSPA            PK      SES E  
Sbjct: 423 TRKSRVSVSP-GRTSGKVTKHKGTEKRESPSPA------------PKPRKVELSESEEDK 469

Query: 292 VPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDK 351
               +    VQ      R+     ++ ++G  + S+    + S  K   V     +S  +
Sbjct: 470 GGKMAAADSVQQRRQYRRQN--QQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSR 527

Query: 352 SSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKG 411
           S+      +P P K+  +        R P    T  +   +PA PPR    P   P  + 
Sbjct: 528 SA------SPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRR- 580

Query: 412 TYTFDIDKWDDPNFNP-FSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPS 470
                      P+  P   S S  + SP + Q+ Y+  P        P K  + +P  P 
Sbjct: 581 ----------TPSPPPRRRSPSPRRYSPPI-QRRYSPSP--------PPKRRTASPPPPP 621

Query: 471 KSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRS---PLSDPPSQD 527
           K  AS   P     ++       + P  K+++P  +   R   SP RS     S  P++ 
Sbjct: 622 KRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKR 681

Query: 528 PTPAATPETPPVISA 542
            +P+  P  P   S+
Sbjct: 682 HSPSPRPRAPQTSSS 696



 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 124/572 (21%), Positives = 195/572 (34%), Gaps = 86/572 (15%)

Query: 20  SEAMSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPD 79
           S A  S S  +  +  S +P K PP     PP        S  PP           P P 
Sbjct: 351 SSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPK 410

Query: 80  GPRSDSVEGS-PFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAK 138
              S + + S   R    S S      K     GT   +  +          +PR  +  
Sbjct: 411 TRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPS-------PAPKPRKVELS 463

Query: 139 NQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALA---------PD 189
             E     +  + DSV   +    R  + Q+S   G+SSS   E    +           
Sbjct: 464 ESEEDKGGKMAAADSV--QQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRR 521

Query: 190 AYSTGSSSASSTLKRTKK----------PRPPSLKKKQT-------TKKPTETPPVKETQ 232
            +S   S++ S  KR K+          P PP  +++++        ++ T TPP +   
Sbjct: 522 RHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRT 581

Query: 233 QEPDEESLVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVV 292
             P      PS    +   +    +   PSP     T   P    + A P          
Sbjct: 582 PSPPPRRRSPSPRRYSPPIQ----RRYSPSPPPKRRTASPPPPPKRRASP---------S 628

Query: 293 PPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKS 352
           PP     RV +SPP  +++ P+T        +PS S       +   S R      E +S
Sbjct: 629 PPPK--RRVSHSPPPKQRSSPVTK-----RRSPSLSSKHRKGSSPSRSTR------EARS 675

Query: 353 SWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPP-----RSPAEPNDIP 407
              N++ +P P  +  +   +  P+RR        +   +P++ P     R+P EP  I 
Sbjct: 676 PQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTP-EPKKIK 734

Query: 408 IAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPS 467
            A       + +         S     ++ P  P    +  P T      P K  +K+P 
Sbjct: 735 KAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVK-KAKSP- 792

Query: 468 SPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRV-KKSPKRSPLSDPPSQ 526
           +PS SP     P ++ +    +G G  K  KK K   K    +  KK  K   ++   + 
Sbjct: 793 TPSPSP-----PRNSDQ----EGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAA 843

Query: 527 DPTPAATPETPPVISAVVHATDEEKLAVTNQK 558
             TPAA      + +A      EE +A    K
Sbjct: 844 AVTPAA------IAAATTTLAQEEPVAAPEPK 869


>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sapiens]
          Length = 2524

 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 93/399 (23%), Positives = 134/399 (33%), Gaps = 79/399 (19%)

Query: 20   SEAMSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVST---------QPPPEEPGC 70
            +EA     +   + P +      PP PP PPPE IP P   T          PPP  P  
Sbjct: 756  TEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPP-- 813

Query: 71   GSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTL 130
             S + P P  P+ +  E +   PP        +E KP A+             VDT +  
Sbjct: 814  -SPSAPPPVVPKEEKEEETAAAPPVEE----GEEQKPPAAEEL---------AVDTGKAE 859

Query: 131  EPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAP-D 189
            EP  S+   +  +   + K  ++   +        +L+A   +G S        + AP D
Sbjct: 860  EPVKSECTEEAEEGPAKGKDAEAAEATAEG-----ALKAEKKEGGSGRATTAKSSGAPQD 914

Query: 190  AYSTGSSSASST-------LKRTKKPRP----------------PSLKKKQTTKKPTETP 226
            + S+ + SA            R   PRP                  L  KQ  ++    P
Sbjct: 915  SDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRAAAIP 974

Query: 227  PVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLE---ETPLEPAVGPKA---- 279
            P+     EP  E   P          T+ A    P P  L+   + P +P   P+     
Sbjct: 975  PIVTKVHEPPREDAAP----------TKPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRS 1024

Query: 280  -ACPLDSESAEGVVPP--ASGGGRVQNSPPVGRKTLPLTTAP----EAGEVTPSDSGGQE 332
             A P D E+ + V  P  A+   ++   PP     LP    P    +A    P  S    
Sbjct: 1025 PAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVPPREVIKASPHAPDPSAFSY 1084

Query: 333  DSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKP 371
              P   L + L  D +           NPPP     K P
Sbjct: 1085 APPGHPLPLGLH-DTARPVLPRPPTISNPPPLISSAKHP 1122



 Score = 40.0 bits (92), Expect = 0.011
 Identities = 52/246 (21%), Positives = 83/246 (33%), Gaps = 27/246 (10%)

Query: 181  PEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESL 240
            P      P + +TG+ +          P PP + K++  ++    PPV+E      EE  
Sbjct: 791  PAPTEPTPASEATGAPTPPPAPPSPSAP-PPVVPKEEKEEETAAAPPVEE-----GEEQK 844

Query: 241  VPSGENLASET-------KTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVP 293
             P+ E LA +T       K+E  +     PA  ++     A    A      E   G   
Sbjct: 845  PPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGSGRAT 904

Query: 294  PASGGGRVQNSPPVGRKTLPLTTAPEAGE-----------VTPSDSGGQEDSPAKGLSVR 342
             A   G  Q+S      +       E G+           +TP+       SP K L ++
Sbjct: 905  TAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLK 964

Query: 343  LEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKK---TPEKLDNTPASPPRS 399
                 +        +   PP       KP    P     ++     P++  ++P    RS
Sbjct: 965  QLKQRAAAIPPIVTKVHEPPREDAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRS 1024

Query: 400  PAEPND 405
            PA P D
Sbjct: 1025 PAPPAD 1030



 Score = 30.8 bits (68), Expect = 6.8
 Identities = 42/182 (23%), Positives = 78/182 (42%), Gaps = 29/182 (15%)

Query: 840  EREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMI--EDEQREKSVSHQTVQ---QLVL 894
            E EVSE  D   E      +MR++       I  M+   D+QR K ++   +      V 
Sbjct: 369  EHEVSEIIDGLSEQENLEKQMRQLAV-----IPPMLYDADQQRIKFINMNGLMADPMKVY 423

Query: 895  EKEQALADLNSVEK-SLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQ 953
            +  Q +   +  EK +  + F ++ K   ++  F + + V +     YL+   K+ + Y+
Sbjct: 424  KDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLT---KKNENYK 480

Query: 954  ALKVHAEEKLDRANAEIAQVRGKAQQEQAAHQASLRKEQL----RVDALERTLEQKNKEI 1009
            +L   +  +           RGK+QQ+Q   Q   +++Q     R    E+  ++K KE 
Sbjct: 481  SLVRRSYRR-----------RGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEA 529

Query: 1010 EE 1011
            E+
Sbjct: 530  EK 531


>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
            sapiens]
          Length = 1937

 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 76/353 (21%), Positives = 145/353 (41%), Gaps = 47/353 (13%)

Query: 682  ESHLQVPEKSSQKELEAMGLGTPSEAIEITAPEGSFASADALLSRLAHPVSLCGALDYLE 741
            E  LQ   K  Q  +E +G    +E       E   +     L  ++  +   G     +
Sbjct: 1104 EIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQ 1163

Query: 742  PDLAEKNPPLFAQKLQEELEFAIMRIEALKLARQIALASRSHQDAKREAAHPTDVSISKT 801
             +L +K    F QKL+ +LE A ++ EA+     +A   + H D+  E     D      
Sbjct: 1164 VELNKKREAEF-QKLRRDLEEATLQHEAM-----VAALRKKHADSMAELGEQIDN----- 1212

Query: 802  ALYSRIGTAEVEKPAGLLFQQPDLDSALQIARAEIITK------------EREVSEWKDK 849
                R+     ++ + L  +  DL S      AE I+K            E +VSE K K
Sbjct: 1213 --LQRVKQKLEKEKSELKMETDDLSS-----NAEAISKAKGNLEKMCRSLEDQVSELKTK 1265

Query: 850  YEESRREVMEM-------RKIVAEYEKTIAQ---MIEDEQREKSVSHQTVQQLVLEKEQA 899
             EE +R + ++       +    EY + + +   ++    R K  S Q +++L  + E+ 
Sbjct: 1266 EEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEE 1325

Query: 900  LADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHA 959
                N++  +L       + ++E  E  ++ +  L+R   +  S V +   +Y+   +  
Sbjct: 1326 TKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQR 1385

Query: 960  EEKLDRANAEIAQVRGKAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEEL 1012
             E+L+ A  ++AQ   +A++   A  A       +  +LE+T ++   E+E+L
Sbjct: 1386 TEELEEAKKKLAQRLQEAEEHVEAVNA-------KCASLEKTKQRLQNEVEDL 1431



 Score = 51.2 bits (121), Expect = 5e-06
 Identities = 63/259 (24%), Positives = 117/259 (45%), Gaps = 28/259 (10%)

Query: 771  KLARQIALASRSHQ----DAKREAAHPTDVSISKTALYSRI----GTAEVEKPAGLLFQQ 822
            KL+++      +HQ    D + E      ++ +KT L  ++    G+ E EK   +  ++
Sbjct: 994  KLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLER 1053

Query: 823  PD--LDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQR 880
                L+  L++A+   +  E +  +  +K E+      E+  ++++ E   A  I+ +++
Sbjct: 1054 AKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKE---FEISNLISKIEDEQAVEIQLQKK 1110

Query: 881  EKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQE 940
             K +  + +++L  E E   A     EK  +DL R  E++ E LE     E      AQ 
Sbjct: 1111 IKELQAR-IEELGEEIEAERASRAKAEKQRSDLSRELEEISERLE-----EAGGATSAQV 1164

Query: 941  YLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQEQAAHQASLRKEQLRVDALER 1000
             L+  KK E  +Q L+   EE   +  A +A +R K       H  S+ +   ++D L+R
Sbjct: 1165 ELN--KKREAEFQKLRRDLEEATLQHEAMVAALRKK-------HADSMAELGEQIDNLQR 1215

Query: 1001 TLEQKNKEIEELTKICDEL 1019
              ++  KE  EL    D+L
Sbjct: 1216 VKQKLEKEKSELKMETDDL 1234



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 57/289 (19%), Positives = 134/289 (46%), Gaps = 33/289 (11%)

Query: 757  QEELEFAIMRIEALKLARQIALASRSHQDAKREAAHPTDVSI-SKTALYSRI------GT 809
            ++ELE  ++ +  LK    + L  +S  D+  +A    +  I +K  L ++I        
Sbjct: 873  RKELEEKMVTL--LKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQLEAKIKEVTERAE 930

Query: 810  AEVEKPAGLLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEK 869
             E E  A L  ++  L+      + +I   E  +++ + +   +  +V  + + +A  ++
Sbjct: 931  EEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDE 990

Query: 870  TIAQMIEDEQREKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRK 929
            TIA++ ++++  +    QT+  L  E+++    +N + K+   L ++ + ++  LE  +K
Sbjct: 991  TIAKLSKEKKALQETHQQTLDDLQAEEDK----VNILTKAKTKLEQQVDDLEGSLEQEKK 1046

Query: 930  NEEVLKRCAQEYLSRVKKEEQRYQAL---KVHAEEKLDRANAEIAQVRGKAQQEQAAH-- 984
                L+R  ++    +K  ++    +   K   +EKL++   EI+ +  K + EQA    
Sbjct: 1047 LRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQ 1106

Query: 985  -QASLRKEQLRVDALERTLEQK--------------NKEIEELTKICDE 1018
             Q  +++ Q R++ L   +E +              ++E+EE+++  +E
Sbjct: 1107 LQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEE 1155



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 50/220 (22%), Positives = 96/220 (43%), Gaps = 26/220 (11%)

Query: 822  QPDLDSALQIARAEIITKEREVSE-WKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQR 880
            Q DL   L I        + E+ E W    +  R   +  ++++   E+   Q++  +  
Sbjct: 1667 QEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERV--QLLHTQNT 1724

Query: 881  E----KSVSHQTVQQLVLEKEQALADLNSVE----KSLADLFRRYEKMKEV------LEG 926
                 K      V QL  E E+ + +  + E    K++ D     E++K+       LE 
Sbjct: 1725 SLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLER 1784

Query: 927  FRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQEQAAHQA 986
             +KN   L++  ++   R+ + EQ   ALK   ++++ +  A + ++ G+ + EQ  +  
Sbjct: 1785 MKKN---LEQTVKDLQHRLDEAEQL--ALK-GGKKQIQKLEARVRELEGEVENEQKRNAE 1838

Query: 987  S---LRKEQLRVDALERTLEQKNKEIEELTKICDELIAKM 1023
            +   LRK + RV  L    E+  K +  L  + D+L AK+
Sbjct: 1839 AVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKV 1878



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 65/294 (22%), Positives = 122/294 (41%), Gaps = 27/294 (9%)

Query: 740  LEPDLAEKNPPLFAQKLQEELEFAIMRIEALKLARQIALASRSHQDAKREAAHPTDVSIS 799
            L+  L++ N  +   + + E + AI R E L+ A++         +   EA +    S+ 
Sbjct: 1360 LQRALSKANSEVAQWRTKYETD-AIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLE 1418

Query: 800  KTALYSRIGTAEVEKPAGLLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREV-- 857
            KT    R+   EVE    L+      ++A      +    ++ +SEWK KYEE++ E+  
Sbjct: 1419 KTK--QRLQN-EVED---LMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEA 1472

Query: 858  ---------MEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQL---VLEKEQALADLNS 905
                      E+ K+   YE+++ Q +E  +RE     Q +  L   + E  + + +L  
Sbjct: 1473 SQKESRSLSTELFKVKNVYEESLDQ-LETLRRENKNLQQEISDLTEQIAEGGKQIHELEK 1531

Query: 906  VEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDR 965
            ++K +       +   E  E   ++EE      Q  L++VK E  R  A K    ++L R
Sbjct: 1532 IKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKR 1591

Query: 966  ANAEIAQVRGKAQQEQAAHQASLRKEQLRV-DALERTLEQKNKEIEELTKICDE 1018
             +  + +      Q     +   R + LRV   +E  L +   ++    ++  E
Sbjct: 1592 NHTRVVE----TMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAE 1641



 Score = 39.3 bits (90), Expect = 0.019
 Identities = 43/200 (21%), Positives = 88/200 (44%), Gaps = 31/200 (15%)

Query: 835  EIITKEREVSEWKD---KYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQ 891
            E+ T + E  + KD   K E  R+E+ E    + + +  +   ++ E    + + +  +Q
Sbjct: 851  EMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQ 910

Query: 892  LVLEKEQALADLNSV-------EKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSR 944
            L+  K Q  A +  V       E+  A+L  +  K+++     +K+ + L+      L++
Sbjct: 911  LIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELT----LAK 966

Query: 945  VKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQEQAAHQASL---------------- 988
            V+KE+   +    +  E++   +  IA++  + +  Q  HQ +L                
Sbjct: 967  VEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKA 1026

Query: 989  -RKEQLRVDALERTLEQKNK 1007
              K + +VD LE +LEQ+ K
Sbjct: 1027 KTKLEQQVDDLEGSLEQEKK 1046



 Score = 37.4 bits (85), Expect = 0.073
 Identities = 50/268 (18%), Positives = 117/268 (43%), Gaps = 13/268 (4%)

Query: 753  AQKLQEELEFAIMRIEALKLARQIALASRSHQDAKREAAHPTDVSISKTALYSRIGTAEV 812
            A  LQ E+E     +E  + +R+IA         + +  H  + S+  T        +++
Sbjct: 1681 ANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQL 1740

Query: 813  EKPAGLLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIA 872
            +     + Q+    +A + A+ + IT    ++E   K +++   +  M+K + +  K + 
Sbjct: 1741 QSEVEEVIQESR--NAEEKAK-KAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQ 1797

Query: 873  QMIED-EQREKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKNE 931
              +++ EQ       + +Q+L     +   ++ + +K  A+  +   K +  ++      
Sbjct: 1798 HRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQT 1857

Query: 932  EVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRG-KAQQEQAAHQASLRK 990
            E  ++        V K + + ++ K  AEE  +++NA +++ R  + + E+A  +A + +
Sbjct: 1858 EEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAE 1917

Query: 991  EQLRVDALERTLEQKNKEIEELTKICDE 1018
             Q+        L  K++E+   TKI  E
Sbjct: 1918 SQV------NKLRVKSREVH--TKISAE 1937



 Score = 30.8 bits (68), Expect = 6.8
 Identities = 37/202 (18%), Positives = 86/202 (42%), Gaps = 16/202 (7%)

Query: 824  DLDSALQIARAEIITKEREVSEWKD----KYEESRREVMEMRKIVAEYEKTIAQMIEDEQ 879
            + +++L+    +I+  + E+++ K     K  E   E+ ++++      +T+   ++ E 
Sbjct: 1549 EAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEI 1608

Query: 880  REKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQ 939
            R ++ + +  +++  +  +    LN   +  A+  R Y   + +L+  + + +   R  +
Sbjct: 1609 RSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQE 1668

Query: 940  EYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQEQAAHQASLRKEQLRVD--- 996
            +   ++   E+R   L+   EE    A  E  + R +   EQ    AS R + L      
Sbjct: 1669 DLKEQLAIVERRANLLQAEIEELW--ATLEQTE-RSRKIAEQELLDASERVQLLHTQNTS 1725

Query: 997  ------ALERTLEQKNKEIEEL 1012
                   LE  + Q   E+EE+
Sbjct: 1726 LINTKKKLENDVSQLQSEVEEV 1747


>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sapiens]
          Length = 2462

 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 94/400 (23%), Positives = 137/400 (34%), Gaps = 80/400 (20%)

Query: 20   SEAMSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVST---------QPPPEEPGC 70
            +EA     +   + P +      PP PP PPPE IP P   T          PPP  P  
Sbjct: 739  TEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPP-- 796

Query: 71   GSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTL 130
             S + P P  P+ +  E +   PP        +E KP A+             VDT +  
Sbjct: 797  -SPSAPPPVVPKEEKEEETAAAPPVEE----GEEQKPPAAEEL---------AVDTGKAE 842

Query: 131  EPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAP-D 189
            EP  S+   +  +   + K  ++   +        +L+A   +G S        + AP D
Sbjct: 843  EPVKSECTEEAEEGPAKGKDAEAAEATAEG-----ALKAEKKEGGSGRATTAKSSGAPQD 897

Query: 190  AYSTGSSSASST-------LKRTKKPRP----------------PSLKKKQTTKKPTETP 226
            + S+ + SA            R   PRP                  L  KQ  ++    P
Sbjct: 898  SDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRAAAIP 957

Query: 227  PVKETQ-QEPDEESLVPSGENLASETKTESAKTEGPSPALLE---ETPLEPAVGPKA--- 279
            P++ T+  EP  E   P          T+ A    P P  L+   + P +P   P+    
Sbjct: 958  PIQVTKVHEPPREDAAP----------TKPAPPAPPPPQNLQPESDAPQQPGSSPRGKSR 1007

Query: 280  --ACPLDSESAEGVVPP--ASGGGRVQNSPPVGRKTLPLTTAP----EAGEVTPSDSGGQ 331
              A P D E+ + V  P  A+   ++   PP     LP    P    +A    P  S   
Sbjct: 1008 SPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVPPREVIKASPHAPDPSAFS 1067

Query: 332  EDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKP 371
               P   L + L  D +           NPPP     K P
Sbjct: 1068 YAPPGHPLPLGLH-DTARPVLPRPPTISNPPPLISSAKHP 1106



 Score = 39.3 bits (90), Expect = 0.019
 Identities = 53/249 (21%), Positives = 84/249 (33%), Gaps = 32/249 (12%)

Query: 181  PEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESL 240
            P      P + +TG+ +          P PP + K++  ++    PPV+E      EE  
Sbjct: 774  PAPTEPTPASEATGAPTPPPAPPSPSAP-PPVVPKEEKEEETAAAPPVEE-----GEEQK 827

Query: 241  VPSGENLASET-------KTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVP 293
             P+ E LA +T       K+E  +     PA  ++     A    A      E   G   
Sbjct: 828  PPAAEELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGSGRAT 887

Query: 294  PASGGGRVQNSPPVGRKTLPLTTAPEAGE-----------VTPSDSGGQEDSPAKGLSVR 342
             A   G  Q+S      +       E G+           +TP+       SP K L ++
Sbjct: 888  TAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLK 947

Query: 343  ------LEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASP 396
                        +     +  +E+  PTK     P    P         P++  ++P   
Sbjct: 948  QLKQRAAAIPPIQVTKVHEPPREDAAPTKPA--PPAPPPPQNLQPESDAPQQPGSSPRGK 1005

Query: 397  PRSPAEPND 405
             RSPA P D
Sbjct: 1006 SRSPAPPAD 1014



 Score = 34.7 bits (78), Expect = 0.47
 Identities = 27/106 (25%), Positives = 35/106 (33%), Gaps = 5/106 (4%)

Query: 8    QPAPASDLNLEASEAMSSDSEEAFETP-ESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPE 66
            +P     L   A+        +  E P E   P K  P  PPPP  + PE +   QP   
Sbjct: 942  KPLDLKQLKQRAAAIPPIQVTKVHEPPREDAAPTKPAPPAPPPPQNLQPESDAPQQPGSS 1001

Query: 67   EPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSG 112
              G      P    P     E   F P   + +     D P  +SG
Sbjct: 1002 PRGKSRSPAP----PADKEAEKPVFFPAFAAEAQKLPGDPPCWTSG 1043



 Score = 30.8 bits (68), Expect = 6.8
 Identities = 42/182 (23%), Positives = 78/182 (42%), Gaps = 29/182 (15%)

Query: 840  EREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMI--EDEQREKSVSHQTVQ---QLVL 894
            E EVSE  D   E      +MR++       I  M+   D+QR K ++   +      V 
Sbjct: 369  EHEVSEIIDGLSEQENLEKQMRQLAV-----IPPMLYDADQQRIKFINMNGLMADPMKVY 423

Query: 895  EKEQALADLNSVEK-SLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQ 953
            +  Q +   +  EK +  + F ++ K   ++  F + + V +     YL+   K+ + Y+
Sbjct: 424  KDRQVMNMWSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLT---KKNENYK 480

Query: 954  ALKVHAEEKLDRANAEIAQVRGKAQQEQAAHQASLRKEQL----RVDALERTLEQKNKEI 1009
            +L   +  +           RGK+QQ+Q   Q   +++Q     R    E+  ++K KE 
Sbjct: 481  SLVRRSYRR-----------RGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEA 529

Query: 1010 EE 1011
            E+
Sbjct: 530  EK 531


>gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]
          Length = 2089

 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 127/577 (22%), Positives = 199/577 (34%), Gaps = 100/577 (17%)

Query: 17   LEASEAMSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVP 76
            + A+E +S   +E+   P++  P   P AP PP   +  + +    PPP          P
Sbjct: 1020 IRAAEKVSRGDQES---PDACLPPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKP 1076

Query: 77   VPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASD 136
                 R D  + +P  P S        + K      +    F             P  S 
Sbjct: 1077 TVRKTRQDGSQEAPEAPLSSELEPFHPKPKIRTRKSSRMTPF-------------PATSA 1123

Query: 137  AKNQEGKVNTRRKSTDSVPISKSTLSRS----------LSLQASDFDGASSSGNPEAVAL 186
            A       +T +  T   P S++T SR+          +   A +   ++S+  P  V  
Sbjct: 1124 APEPHPSTSTAQPVTPK-PTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQP--VTS 1180

Query: 187  APDAYSTGSSSASSTLK--RTKKPRPPSLKKKQTTKKPTETPPV-------KETQQEPDE 237
             P +  T    + S++K   T  P    L+   +T +P  + P        K        
Sbjct: 1181 EPTSQVTRGRKSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTP 1240

Query: 238  ESLVPSGENLASETKTESAKTEGPSPALLE--------ETPLEPAVGPKAACPLDSESAE 289
            E +VP+   L   T T+   T  P+             +TP EP V P A     S S +
Sbjct: 1241 EPVVPTAPELQPSTSTDQPVTSEPTYQATRGRKNRSSVKTP-EPVV-PTAPELRPSTSTD 1298

Query: 290  GVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSP-AKGLSVRLEFDYS 348
              V P       ++   +     P T  P A E+  S S  Q  +P     + R   + S
Sbjct: 1299 RPVTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMS 1358

Query: 349  EDK---SSWDNQQENPPPTKKIGKKPVAKMPLRRP-------KMKKTPEKLDNTPASPPR 398
              K   S+     E PP T    ++PV   P  R           KTPE L   P +P  
Sbjct: 1359 SVKNPESTVPIAPELPPSTST--EQPVTPEPTSRATRGRKNRSSGKTPETL--VPTAPKL 1414

Query: 399  SPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSK---MQESPKLPQQSYNFDPD----- 450
             P+   D P+                  P S  ++    + S K P+      P+     
Sbjct: 1415 EPSTSTDQPVTP---------------EPTSQATRGRTNRSSVKTPETVVPTAPELQPST 1459

Query: 451  TCDESVDPFKTSSKTPSSPSKS---------PASFEIPASAMEANGVDGDGLNKP--AKK 499
            + D+ V P  TS  T     +S         P + E+ ASA     V  +  ++    +K
Sbjct: 1460 STDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEPTSRTTRGRK 1519

Query: 500  KKTPLKTDTFRVKKSPKRSP---LSDPPSQDPTPAAT 533
             ++ +KT    V  +P+  P      P + +PT  AT
Sbjct: 1520 NRSSVKTPETVVPAAPELQPSTSTDQPVTPEPTSRAT 1556


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 61.2 bits (147), Expect = 5e-09
 Identities = 163/793 (20%), Positives = 258/793 (32%), Gaps = 117/793 (14%)

Query: 3    GSQSLQPAPASDLNLEASEAMSSDSEEAFETPESTTPVKAPPAPPPPPPEVIP------- 55
            GS  L   P S   + +SEA +  +       + TT  +A  +PP      +P       
Sbjct: 450  GSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEG 509

Query: 56   -----EPEVSTQPPPEEPGCGSETVPVPDG-PRSDSVEGS-----------PFRPPSHSF 98
                    VST P          T PV    P + S E S           P   PS   
Sbjct: 510  STPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGS 569

Query: 99   SAVFDEDKPIASSGTYNLDFDNIELV----DTFQTLEPRASDAK-NQEG-KVNTRRKSTD 152
            + +   + P+++    + +           +TF T    AS +    EG  + T   S  
Sbjct: 570  TPL--TNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSER 627

Query: 153  SVPISKSTLSRSL--SLQASDF---------------DGASSSGNPEAVALAPDAYSTGS 195
               I+  ++S +L  S +AS                 +  SSS   E  ++    Y+ GS
Sbjct: 628  GTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGS 687

Query: 196  SSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTES 255
            +  +S    T            TT   T TP    T  E         G ++ + T +E 
Sbjct: 688  TPLTSMPVNTTLVASSEASTLSTTPVDTSTPVT--TSTEASSSPTTADGASMPTSTPSEG 745

Query: 256  AKTEGPSP-----------ALLEETPLEPA----VGPKAAC-PLDSESAEGVVPPASGGG 299
            +      P           + L  TPL+ +       +A+C P  +E     +   S G 
Sbjct: 746  STPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGS 805

Query: 300  RVQNSPPVG--------RKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDK 351
             +  S PV           TL  T       VT S       +PA+G S+     YSE +
Sbjct: 806  PLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTS-TYSEGR 864

Query: 352  SSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPP---RSPAEPNDIPI 408
            +   +    P  T  +    ++ +    P    TP        S P      + P   P 
Sbjct: 865  TPLTSM---PVSTTLVATSAISTLS-TTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPG 920

Query: 409  AKGTYTFDIDKWDDP----NFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSK 464
               T    +     P         S+T     +P          P T + +  P  T S+
Sbjct: 921  EGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSE 980

Query: 465  TPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPP 524
              +  + +P S  + A++      +   L+       TPL T T      P  +  +  P
Sbjct: 981  GTTPLTSTPVSHTLVANS------EASTLSTTPVDSNTPLTTST-EASSPPPTAEGTSMP 1033

Query: 525  SQDPTPAATPET-PPVISAVVHATDEEKLAVTNQKWTCMTVDLEADKQDYPQPSDLSTFV 583
            +  P+  +TP T  PV + +V +++   L+ T         D       Y Q S  ST  
Sbjct: 1034 TSTPSEGSTPLTRMPVSTTMVASSETSTLSTT-------PADTSTPVTTYSQASSSSTTA 1086

Query: 584  NETKFSSPT--EELDYRNSYEIEYMEKIGSSLPQDDDAPKKQALYLMFDTSQESPVKSSP 641
            + T   + T  E      S  +     + S        P         DTS   PV +S 
Sbjct: 1087 DGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTP--------VDTS--IPVTTS- 1135

Query: 642  VRMSESPTPCSGSSFEETEALVNTAAKNQHPVPRGLAPNQESHL--QVPEKSSQKELEAM 699
               S SPT   G+S   +     T      PV   L  + E++     P  S  +   + 
Sbjct: 1136 TEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATST 1195

Query: 700  GLGTPSEAIEITA 712
               +P    E+T+
Sbjct: 1196 EASSPPPTAEVTS 1208



 Score = 61.2 bits (147), Expect = 5e-09
 Identities = 156/730 (21%), Positives = 252/730 (34%), Gaps = 99/730 (13%)

Query: 3    GSQSLQPAPASDLNLEASEAMS------------SDSEEAFETPESTTPVKAPPAPPPPP 50
            GS  L   P S + + +SEA +            + S EA  +P +      P +PP   
Sbjct: 2395 GSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEG 2454

Query: 51   PEVIPEPEVSTQPPPEEPGCGSETVPVPDG-PRSDSVEGS-----------PFRPPSHS- 97
               +    VST P          T PV    P + S E S           P    S   
Sbjct: 2455 TTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGS 2514

Query: 98   --FSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEG-KVNTRRKSTDSV 154
               +++     P+AS     L    ++      T    +S A + EG  + T   S  S 
Sbjct: 2515 TLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGST 2574

Query: 155  PISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP-RPPSL 213
            P+    +S +  L +S+   AS+          P   ST +SS+ +T K T  P   PS 
Sbjct: 2575 PLRSMPVS-TKPLASSE---ASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSE 2630

Query: 214  KKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEETPLEP 273
                 T     T PV  ++      + V +   + + T T S+ T     ++   TP E 
Sbjct: 2631 VSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGE- 2689

Query: 274  AVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQED 333
                  + PL +      +  A+      ++ PV   T P+TT+ EA             
Sbjct: 2690 -----RSTPLTNILVSTTL-LANSEASTLSTTPVDTST-PVTTSAEA---------SSSP 2733

Query: 334  SPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKL---D 390
            + A+G S+R+         S  +    P  +  +   PVA               +    
Sbjct: 2734 TTAEGTSMRI---------STPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTT 2784

Query: 391  NTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNP--------FSSTSKMQESPKLPQ 442
            +T AS   + AE   +P +  + T         N  P         S+T     +P    
Sbjct: 2785 STEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTS 2844

Query: 443  QSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKT 502
               +  P T +  V P  T+S+  +  +  P S   P ++ EA+      L+        
Sbjct: 2845 TKASSSPTTAEGIVVPISTASEGSTLLTSIPVS-TTPVASSEAS-----TLSTTPVDTSI 2898

Query: 503  PLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCM 562
            P+ T T     SP  +  +  P   P+  +TP T  ++S V  A  E     T    T  
Sbjct: 2899 PVTTST-EGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRT 2957

Query: 563  TVDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKK 622
             V   A+    P  ++ ++       S+P E      S  +  M    S        P  
Sbjct: 2958 PVTTSAEASSSPTTAEGTSM----PISTPGERRTPLTSMSVSTMPVASSEASTLSRTPA- 3012

Query: 623  QALYLMFDTSQESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHPVPRGLAPNQE 682
                   DTS  +PV +S    S SPT   G+        ++T ++   P+     P   
Sbjct: 3013 -------DTS--TPVTTS-TEASSSPTTAEGTGIP-----ISTPSEGSTPLTS--IPVST 3055

Query: 683  SHLQVPEKSS 692
            + + +PE S+
Sbjct: 3056 TPVAIPEAST 3065



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 136/719 (18%), Positives = 238/719 (33%), Gaps = 101/719 (14%)

Query: 4    SQSLQPAPASDLNLEASEAMSSDSEEAFET-PESTTPVKAPPAPPPPPPEVIPEPEVSTQ 62
            S   + +P +        +  S+    F + P ST PV    A       V     V+T 
Sbjct: 2195 STEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTS 2254

Query: 63   PPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIE 122
                     +E   +P    S+        P SH+          +A+S    L    ++
Sbjct: 2255 TEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTL---------VANSEVSTLSTTPVD 2305

Query: 123  LVDTFQTLEPRASDAKNQEG-KVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNP 181
                F T    +S     EG  + T   S  + P+++  +S ++    + F+ ++ S  P
Sbjct: 2306 SNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTM---VASFETSTLSTTP 2362

Query: 182  EAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLV 241
               +     YS   SS ++    +      S      T  P  T PV  ++      + V
Sbjct: 2363 ADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPV 2422

Query: 242  PSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRV 301
             +   + + T+  S+ T     ++    P E    P A+ P+ +       P  S     
Sbjct: 2423 DTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTT-PLASMPVST------TPVVSSEAGT 2475

Query: 302  QNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENP 361
             ++ PV   T P+TT+ EA             SP     + +    + + S+        
Sbjct: 2476 LSTTPVDTST-PMTTSTEASS-----------SPTTAEDIVVPISTASEGSTL------- 2516

Query: 362  PPTKKIGKKPVAKMPLRRPK---MKKTPEK-----LDNTPASPPRSPAEPNDIPIAKGTY 413
                 +   PV+  P+  P+   +  TP       + +T  S   + AE   +P +  TY
Sbjct: 2517 -----LTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTS--TY 2569

Query: 414  TFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSK-- 471
            +            P  S   +   P    ++        D S+ P  TS++T SSP+   
Sbjct: 2570 S--------EGSTPLRSMP-VSTKPLASSEASTLSTTPVDTSI-PVTTSTETSSSPTTAK 2619

Query: 472  ------------SPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSP 519
                        S +   I  S M     +   L+      +T + T T     SP  + 
Sbjct: 2620 DTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTST-GTSSSPTTAE 2678

Query: 520  LSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTVDLEADKQDYP----- 574
             S  P+  P   +TP T  ++S  + A  E     T    T   V   A+    P     
Sbjct: 2679 GSSMPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEG 2738

Query: 575  ------QPSDLSTFVNETKFSS---PTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQAL 625
                   PSD ST +     S+    + E    ++  ++    + +S          +  
Sbjct: 2739 TSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVT 2798

Query: 626  YLMFDTSQES-------PVKSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHPVPRGL 677
             +   T  E+       PV  +PV  SE+ T  +      T    +T A +      G+
Sbjct: 2799 SMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGI 2857



 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 133/677 (19%), Positives = 229/677 (33%), Gaps = 71/677 (10%)

Query: 10   APASDLNLEASEAMSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPG 69
            A +S    E +   +S   E   TP ++ PV   P        +   P V T  P     
Sbjct: 2788 ASSSPTTAEVTSMPTSTPSET-STPLTSMPVNHTPVASSEAGTLSTTP-VDTSTPVTTST 2845

Query: 70   CGSETVPVPDG---PRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDT 126
              S +    +G   P S + EGS         +++     P+ASS    L    ++    
Sbjct: 2846 KASSSPTTAEGIVVPISTASEGSTL------LTSIPVSTTPVASSEASTLSTTPVDTSIP 2899

Query: 127  FQTLEPRASDAKNQEG-KVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVA 185
              T    +S     EG  +     S  S P++ S L  ++ +  S+   AS+        
Sbjct: 2900 VTTSTEGSSSPTTAEGTSMPISTPSEVSTPLT-SILVSTVPVAGSE---ASTLSTTPVDT 2955

Query: 186  LAPDAYSTGSSSASSTLKRTKKP-RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSG 244
              P   S  +SS+ +T + T  P   P  ++   T     T PV  ++      +   + 
Sbjct: 2956 RTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTS 3015

Query: 245  ENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNS 304
              + + T+  S+ T      +   TP E +  P  + P+ +      +P AS        
Sbjct: 3016 TPVTTSTEASSSPTTAEGTGIPISTPSEGST-PLTSIPVSTTPV--AIPEAS-------- 3064

Query: 305  PPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPT 364
                  TL  T       V  S       +PA+G S+ +   YSE  +       +  P 
Sbjct: 3065 ------TLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPIS-TYSEGSTPLTGVPVSTTPV 3117

Query: 365  KKIGKKPVAKMPLRRPKMKKTPEKLDNTPAS------PPRSPAEPNDIPIAKGTYTFDID 418
                   ++  P+       T  +  ++P +      P  +P+E +         T  + 
Sbjct: 3118 TSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVV 3177

Query: 419  KWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEI 478
              +D       S + +  S  +   +      T + +  P  T S+  +  +  P S   
Sbjct: 3178 SSEDSTL----SATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVS-NT 3232

Query: 479  PASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPP 538
            P ++ EA+      L+       TPL T T     SP  +  +  P+  P+  +TP T  
Sbjct: 3233 PVASSEASI-----LSTTPVDSNTPLTTST-EASSSPPTAEGTSMPTSTPSEGSTPLTSM 3286

Query: 539  VISAVVHATDEEKLAVTNQKWTCMTVDLEADKQDYPQPSDLSTFVNET--KFSSPTEELD 596
             +S    A+ E     T    T   V   +     P  +D ++    T  + S+P   + 
Sbjct: 3287 PVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMS 3346

Query: 597  YRNSYEIEYMEKIGSSLPQDDDAPKKQALYLMFDTSQESPVKSSPVRMSESPTPCSGSSF 656
            +  +  +       S+ P D   P          TS E+         S SPT   G+S 
Sbjct: 3347 FSTTPVVSSEASTLSTTPVDTSTP--------VTTSTEA---------SLSPTTAEGTSI 3389

Query: 657  EETEALVNTAAKNQHPV 673
              +     T      PV
Sbjct: 3390 PTSSPSEGTTPLASMPV 3406



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 126/576 (21%), Positives = 199/576 (34%), Gaps = 92/576 (15%)

Query: 6    SLQPAPASDLNLEASEAMSSDSEEAFETPEST-----TPVKAPPAPPPP----PPEVIPE 56
            S  P   S     ++EA SS + E    P ST     TP+ + P    P       ++  
Sbjct: 3185 SATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILST 3244

Query: 57   PEVSTQPPPEEPGCGSETVPVPDG---PRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGT 113
              V +  P       S + P  +G   P S   EGS         +++      +ASS T
Sbjct: 3245 TPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGST------PLTSMPVSTTTVASSET 3298

Query: 114  YNLDFDNIELVDTFQTLEPRASDAKNQEG-KVNTRRKSTDSVPISKSTLSRSLSLQASDF 172
              L     +      T    +S     +G  + T   S  S P++  + S +  + +   
Sbjct: 3299 STLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSE-- 3356

Query: 173  DGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRP-PSLKKKQTTKKPTETPPVKET 231
              AS+          P   ST +S + +T + T  P   PS         P  T PV   
Sbjct: 3357 --ASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPV--V 3412

Query: 232  QQEPDEESLVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGV 291
              E +  S  P   N    T TE++     SP + E T L  +   + + PL S      
Sbjct: 3413 SSEVNTLSTTPVDSNTLVTTSTEASS----SPTIAEGTSLPTSTTSEGSTPL-SIMPLST 3467

Query: 292  VPPASGGGRVQNSPPVGRKTLPLTTA------PEAGEVT--PSDSGGQEDSPAKGLSVRL 343
             P AS      ++ PV   T P+TT+      P   EVT  P+ + G+  +P   + V  
Sbjct: 3468 TPVASSEASTLSTTPVDTST-PVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVST 3526

Query: 344  EFDYSEDKSSWD-------------NQQENPPPTKKIGKKPVAKMPLRRPK--------M 382
                S + S+               +Q  + P T +     V  M +  P         M
Sbjct: 3527 TPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQ-----VTTMRMSTPSEGSSSLTTM 3581

Query: 383  KKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQ 442
              +   + ++ AS P +P+     P+   T +       +    P S+ S++  S  L  
Sbjct: 3582 LLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEV--STPLTI 3639

Query: 443  QSYNFDPDTCDES-------VD---PFKTSSKTPSSP--------------SKSPASFEI 478
               +    T  E+       VD   P  TS++  SSP                S     +
Sbjct: 3640 MPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTM 3699

Query: 479  PASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKS 514
            P S       +G  L+ P+    TP+ T T  +  S
Sbjct: 3700 PVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAISSS 3735



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 154/761 (20%), Positives = 243/761 (31%), Gaps = 141/761 (18%)

Query: 4    SQSLQPAPASDLNLEASEAMSSDSEEAFETPESTTPVKAPPAPPPPPPEVIP-------- 55
            S  L   P +   + +SEA +  +     +   TT  KA  +P      V+P        
Sbjct: 2809 STPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGS 2868

Query: 56   ----EPEVSTQPPPEEPGCGSETVPVPDG-PRSDSVEGS-----------PFRPPSH--- 96
                   VST P          T PV    P + S EGS           P   PS    
Sbjct: 2869 TLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVST 2928

Query: 97   SFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPI 156
              +++     P+A S    L    ++      T    +S     EG          S+PI
Sbjct: 2929 PLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGT---------SMPI 2979

Query: 157  SKS------TLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP-R 209
            S          S S+S        AS+     A    P   ST +SS+ +T + T  P  
Sbjct: 2980 STPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPIS 3039

Query: 210  PPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKT----------- 258
             PS      T  P  T PV   +      + V S   + + T+  S+ T           
Sbjct: 3040 TPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPIST 3099

Query: 259  --EGPSPAL---LEETPL-EPAVGPKAACPLDSE-----SAEGVVPPASGGGRVQNSPPV 307
              EG +P     +  TP+   A+   +  P+D+      S E    P +  G    +   
Sbjct: 3100 YSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTP 3159

Query: 308  GRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKI 367
               + PLT  P +  +  S       +     S  +        S+       P  T   
Sbjct: 3160 SEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSE 3219

Query: 368  GKKPVAKMPLRR-PKMKKTPEKLDNTPA---SPPRSPAEPNDIP-IAKGTYTFDIDKWDD 422
            G  P+  +P+   P        L  TP    +P  +  E +  P  A+GT          
Sbjct: 3220 GMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSM-------- 3271

Query: 423  PNFNPFSSTSKMQESPKLPQQSYNFDPDTCD----ESVDPFKTSSKTPSSP-----SKSP 473
            P   P   ++ +   P       + +  T      ++  P  T S+  SSP     +  P
Sbjct: 3272 PTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMP 3331

Query: 474  ASFEIPASAMEAN---------GVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPP 524
             S     S    N           +   L+       TP+ T T     SP  +  +  P
Sbjct: 3332 TSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTST-EASLSPTTAEGTSIP 3390

Query: 525  SQDPTPAATP-ETPPVISAVVHATDEEKLAVTNQKWTCMTVDLEADKQDYPQPSDLSTFV 583
            +  P+   TP  + PV +  V +++   L+ T                    P D +T V
Sbjct: 3391 TSSPSEGTTPLASMPVSTTPVVSSEVNTLSTT--------------------PVDSNTLV 3430

Query: 584  NETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQALYLM-----------FDTS 632
              +  +S +  +              G+SLP    +     L +M             T 
Sbjct: 3431 TTSTEASSSPTIAE------------GTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTL 3478

Query: 633  QESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHPV 673
              +PV +S    + SPT  S ++ E T    +TA +   P+
Sbjct: 3479 STTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPL 3519



 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 127/644 (19%), Positives = 222/644 (34%), Gaps = 86/644 (13%)

Query: 34   PESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRSDSVEGSPFRP 93
            P STTPV +  A       +     V+T          +E   +P    S+ +      P
Sbjct: 1755 PVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTP 1814

Query: 94   PSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKST-D 152
             SH+  A    +   ++  T  +D ++  +  T  +  P  ++  +      +   +   
Sbjct: 1815 VSHTLVA----NSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSEGSTALT 1870

Query: 153  SVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPS 212
            S+P+S +T++ S +   S     +S+       ++    +   SS  ++  R  +P   S
Sbjct: 1871 SIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTS 1930

Query: 213  LKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLE-ETPL 271
            +    TT   +E   +  T  +        S    AS + T +  T  P+PA  E  TPL
Sbjct: 1931 IPVSTTTVASSEINTLSTTLADTRTPVTTYSQ---ASSSPTTADGTSMPTPAYSEGSTPL 1987

Query: 272  EP-------AVGPKAAC----PLDSE-----SAEGVVPPASGGGR-VQNSPPVGRKTLPL 314
                      V  +A+     P+D+      S EG   P + GG  +Q S P   +T PL
Sbjct: 1988 TSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTP-SERTTPL 2046

Query: 315  TTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAK 374
               P +  +  S  G             L     + K+   N  E        G      
Sbjct: 2047 AGMPVSTTLVVSSEGNT-----------LSTTPVDSKTQVTNSTEASSSATAEGSSMTIS 2095

Query: 375  MPLR-RPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSK 433
             P    P +   P  L  TP + P           A    T  +D     + +P  ++++
Sbjct: 2096 APSEGSPLLTSIP--LSTTPVASPE----------ASTLSTTPVD-----SNSPVITSTE 2138

Query: 434  MQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGL 493
            +  SP +P +  +    T  +   P           +  P S  + AS+  +       L
Sbjct: 2139 VSSSP-IPTEGTSMQTSTYSDRRTPL----------TSMPVSTTVVASSAIST------L 2181

Query: 494  NKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLA 553
            +       TP+ T++   + SP  S  +  P+  P+  +TP T   +S +   T E    
Sbjct: 2182 STTPVDTSTPV-TNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTL 2240

Query: 554  VTNQKWTCMTVDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIG--S 611
                  T   V    +    P  ++ ++    T     T       S+ +    ++   S
Sbjct: 2241 SATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLS 2300

Query: 612  SLPQDDDAPKKQALYLMFDTSQESPVKSSPVRMSESPTPCSGSS 655
            + P D + P        F TS E+   S P     +  P S SS
Sbjct: 2301 TTPVDSNTP--------FTTSTEA--SSPPPTAEGTSMPTSTSS 2334



 Score = 51.2 bits (121), Expect = 5e-06
 Identities = 138/729 (18%), Positives = 239/729 (32%), Gaps = 140/729 (19%)

Query: 3    GSQSLQPAPASDLNLEASEAMSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQ 62
            GS      P S + +  SEA +  +     +   TT  +A  +P                
Sbjct: 2218 GSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTT-------------- 2263

Query: 63   PPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIE 122
                     +E   +P    S+        P SH+          +A+S    L    ++
Sbjct: 2264 ---------AEGTSIPTSTLSEGTTPLTSIPVSHTL---------VANSEVSTLSTTPVD 2305

Query: 123  LVDTFQTLEPRASDAKNQEG-KVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNP 181
                F T    +S     EG  + T   S  + P+++  +S ++    + F+ ++ S  P
Sbjct: 2306 SNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTM---VASFETSTLSTTP 2362

Query: 182  EAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLV 241
               +     YS   SS ++    +      S      T  P  T PV  ++      + V
Sbjct: 2363 ADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPV 2422

Query: 242  PSGENLASETKTESAKT-------------EGPSPALLEETPLEPAV----GPKAACPLD 284
             +   + + T+  S+ T             EG +P         P V    G  +  P+D
Sbjct: 2423 DTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVD 2482

Query: 285  SE--------------SAEGVVPP---ASGGGRVQNSPPVGRKTLPLTTAPEAG--EVTP 325
            +               +AE +V P   AS G  +  S PV   T P+  +PEA     TP
Sbjct: 2483 TSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPV--STTPV-ASPEASTLSTTP 2539

Query: 326  SDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPL-RRPKMKK 384
             DS    +SP     V    + S   +S +     P  T   G  P+  MP+  +P    
Sbjct: 2540 VDS----NSP-----VVTSTEISSSATSAEG-TSMPTSTYSEGSTPLRSMPVSTKPLASS 2589

Query: 385  TPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQES------- 437
                L  TP            IP+   T T            P S+ S++  S       
Sbjct: 2590 EASTLSTTPVD--------TSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVS 2641

Query: 438  --PKLPQQSYNFDPD--------TCDESVDPFKTSSKTPSSPSKSPASFEIP------AS 481
              P    ++              T         T+++  S P+ +P     P      ++
Sbjct: 2642 TMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVST 2701

Query: 482  AMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVIS 541
             + AN  +   L+       TP+ T       SP  +  +      P+  +TP T  ++S
Sbjct: 2702 TLLANS-EASTLSTTPVDTSTPVTTSA-EASSSPTTAEGTSMRISTPSDGSTPLTSILVS 2759

Query: 542  AVVHATDEEKLAVTNQKWTCMTVDLEADKQDYPQPSDLSTFVNET--KFSSPTEELDYRN 599
             +  A+ E     T    T + V    +    P  +++++    T  + S+P   +   +
Sbjct: 2760 TLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNH 2819

Query: 600  SYEIEYMEKIGSSLPQDDDAP------------KKQALYLMFDTSQES-------PVKSS 640
            +          S+ P D   P              + + +   T+ E        PV ++
Sbjct: 2820 TPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTT 2879

Query: 641  PVRMSESPT 649
            PV  SE+ T
Sbjct: 2880 PVASSEAST 2888



 Score = 50.8 bits (120), Expect = 6e-06
 Identities = 159/747 (21%), Positives = 253/747 (33%), Gaps = 121/747 (16%)

Query: 34   PESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRSDSVEGSPFRP 93
            P+STTPV +  A       V     V+T          +E   +P    S+        P
Sbjct: 930  PDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTP 989

Query: 94   PSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEG-KVNTRRKSTD 152
             SH+          +A+S    L    ++      T    +S     EG  + T   S  
Sbjct: 990  VSHTL---------VANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEG 1040

Query: 153  SVPISKSTLSRSL-------SLQASDFD----------GASSSGNPEAVALAPDAYSTGS 195
            S P+++  +S ++       +L  +  D           +SSS   +  ++    YS GS
Sbjct: 1041 STPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGS 1100

Query: 196  --------------SSASSTLKRTKKPRP-PSLKKKQTTKKPT--------ETPPVKET- 231
                          SS +STL  T      P     + +  PT         +PP + T 
Sbjct: 1101 TPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTT 1160

Query: 232  --QQEPDEESLVPSGE-NLASETKTES-----AKTEGPSPALLEETPLEPAVGP-KAACP 282
                 P   +LV S E N  S T  +S       TE  SP    E    P   P + + P
Sbjct: 1161 PLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTP 1220

Query: 283  LDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVR 342
            L S       P AS      ++ PV   T P+TT+ E              + A+G S+ 
Sbjct: 1221 LTSMPVRH-TPVASSEASTLSTSPVDTST-PVTTSAET---------SSSPTTAEGTSLP 1269

Query: 343  LEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAE 402
                 +   S       + P +  +   P A   L  P   K P    N  +S P +PAE
Sbjct: 1270 -----TSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSP-TPAE 1323

Query: 403  PNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQS--YNFDPDTCDESVDPFK 460
               +P    T T+   +    +  P ++T     +  +   +   N  P T         
Sbjct: 1324 GTSMP----TSTYSEGRTPLTSI-PVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSP 1378

Query: 461  TSSKTPSSPSKSPAS-----FEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSP 515
            T+S+  S P+ +P+        IP S       +   L+       TP  T +     SP
Sbjct: 1379 TTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTP-GTTSAEATSSP 1437

Query: 516  KRSPLSDPPSQDPTPAATP-ETPPVISAVVHATDEEKLAVTNQKWTCMTVDLEADKQDYP 574
              +     P+  P+   TP ++ PV +  V  ++   L+ T        V   A     P
Sbjct: 1438 TTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSS-P 1496

Query: 575  QPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQALYLMFDTSQE 634
             P++ ++       S+P+E      S  +       S +      P              
Sbjct: 1497 TPAEGTSIA----ISTPSEGSTALTSIPVSTTTVASSEINSLSTTP-------------- 1538

Query: 635  SPVKSSPV----RMSESPTPCSGSSFEETEALVNTAAKNQHPVPRGLAPNQESH-LQVPE 689
              V S+PV    + S SPT   G+S + +     +      PV   L  + E++ L    
Sbjct: 1539 -AVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTP 1597

Query: 690  KSSQKELEAMGLGTPSEAIEITAPEGS 716
              S+ ++ A      +EA   T  EGS
Sbjct: 1598 IDSKTQVTA-----STEASSSTTAEGS 1619



 Score = 50.4 bits (119), Expect = 8e-06
 Identities = 125/581 (21%), Positives = 198/581 (34%), Gaps = 95/581 (16%)

Query: 3    GSQSLQPAPASDLNLEASEAMSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQ 62
            G   L   P S+  + +SEA    +         TT  +A  +PP             T 
Sbjct: 3220 GMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAE---------GTS 3270

Query: 63   PPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIE 122
             P   P  GS   P+   P S +                      +ASS T  L     +
Sbjct: 3271 MPTSTPSEGS--TPLTSMPVSTTT---------------------VASSETSTLSTTPAD 3307

Query: 123  LVDTFQTLEPRASDAKNQEG-KVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNP 181
                  T    +S     +G  + T   S  S P++  + S +  + +     AS+    
Sbjct: 3308 TSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSE----ASTLSTT 3363

Query: 182  EAVALAPDAYSTGSSSASSTLKRTKKP-RPPSLKKKQTTKKPTETPPVKETQQEPDEESL 240
                  P   ST +S + +T + T  P   PS         P  T PV     E +  S 
Sbjct: 3364 PVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPV--VSSEVNTLST 3421

Query: 241  VPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGR 300
             P   N    T TE++     SP + E T L  +   + + PL S       P AS    
Sbjct: 3422 TPVDSNTLVTTSTEASS----SPTIAEGTSLPTSTTSEGSTPL-SIMPLSTTPVASSEAS 3476

Query: 301  VQNSPPVGRKT-----LPLTTAPEAGEVT--PSDSGGQEDSPAKGLSVRLEFDYSEDKSS 353
              ++ PV   T      P  ++P   EVT  P+ + G+  +P   + V      S + S+
Sbjct: 3477 TLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEAST 3536

Query: 354  W-------------DNQQENPPPTKKIGKKPVAKMPLRRPK--------MKKTPEKLDNT 392
                           +Q  + P T +     V  M +  P         M  +   + ++
Sbjct: 3537 LSTTPVDSNTFVTSSSQASSSPATLQ-----VTTMRMSTPSEGSSSLTTMLLSSTYVTSS 3591

Query: 393  PASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDTC 452
             AS P +P+     P+   T +       +    P S+ S++     +   S      T 
Sbjct: 3592 EASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVS------TT 3645

Query: 453  DESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKP---AKKKKTPLKT--- 506
              ++    T+S  P   S +P    I ++ + ++ V  +G   P     +  TPL T   
Sbjct: 3646 SVTISEAGTASTLPVDTS-TPV---ITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPV 3701

Query: 507  DTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHAT 547
             T RV  S + S LS P     TP  T       SA + +T
Sbjct: 3702 STTRVTSS-EGSTLSTPSVVTSTPVTTSTEAISSSATLDST 3741



 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 127/617 (20%), Positives = 204/617 (33%), Gaps = 93/617 (15%)

Query: 3    GSQSLQPAPASDLNLEASEAMSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQ 62
            GS SL     S   + +SEA +  +     +   TT  ++   P PP    +P   +ST 
Sbjct: 3574 GSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITLP---MST- 3629

Query: 63   PPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFD----EDKPIASSGTYNLDF 118
              P E       +PV     + S  G+    P  + + V         P+   GT     
Sbjct: 3630 --PSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPEGT----- 3682

Query: 119  DNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSS 178
                   T     P                 S  S P++   +S   + + +  +G++ S
Sbjct: 3683 -------TMPIWTP-----------------SEGSTPLTTMPVS---TTRVTSSEGSTLS 3715

Query: 179  GNPEAVALAPDAYSTGSSSASSTLKRT--KKPRPPSLKKKQTTKKPTETPPVKETQQEPD 236
              P  V   P   ST + S+S+TL  T      P  +    TT   + TP  +       
Sbjct: 3716 -TPSVVTSTPVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTR------F 3768

Query: 237  EESLVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPAS 296
             ES  PS  ++ +     +A     SP  LE T   P         L +      +   S
Sbjct: 3769 PESSTPSIPSVYTSMSMTTASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMS 3828

Query: 297  GGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDN 356
                   S P G  + PL T+ +AG  +          PA+  ++R+         S  +
Sbjct: 3829 PSEASTLSTPPGDTSTPLLTSTKAGSFS---------IPAEVTTIRI---------SITS 3870

Query: 357  QQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFD 416
            ++  P  T  +        P     +  TP    +T  +P    A    IP+A       
Sbjct: 3871 ERSTPLTTLLVSTTLPTSFP--GASIASTPPLDTSTTFTPSTDTASTPTIPVATTISVSV 3928

Query: 417  IDKWDDPN---FNP-----------FSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTS 462
            I +   P    F P           F +T+    +P +     N    +   +   F T+
Sbjct: 3929 ITEGSTPGTTIFIPSTPVTSSTADVFPATTGAVSTPVITSTELNTPSTSSSSTTTSFSTT 3988

Query: 463  SK--TPSSPSKSPASFEIPASAMEANGVDGDGLNKPA---KKKKTPLKTDTFRVKKSPKR 517
             +  TP+  + +P ++   ++A         G    A       TP  T T    +    
Sbjct: 3989 KEFTTPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSASTLSATSTP-HTSTSVTTRPVTP 4047

Query: 518  SPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTVDLEADKQDYPQPS 577
            S  S  PS   +    P  PP  S+    T      V  +  T MT   +   +    P+
Sbjct: 4048 SSESSRPSTITSHTIPPTFPPAHSSTPPTTSASSTTVNPEAVTTMTTRTKPSTRTTSFPT 4107

Query: 578  DLSTFV--NETKFSSPT 592
              +T V  N T  S+PT
Sbjct: 4108 VTTTAVPTNTTIKSNPT 4124



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 155/711 (21%), Positives = 232/711 (32%), Gaps = 114/711 (16%)

Query: 6    SLQPAPASDLNLEASEAMSSDSEEAFETPESTTPVKAPPA------PPPPPPEVIPEPEV 59
            S  P  A   +L  S   S  S      P STT V +P A      P      V+   EV
Sbjct: 1257 SSSPTTAEGTSLPTSTT-SEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEV 1315

Query: 60   STQPPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFD 119
            S+ P P E   G+        P S   EG   R P  S          +ASS    L   
Sbjct: 1316 SSSPTPAE---GTSM------PTSTYSEG---RTPLTSIPV---NTTLVASSAISILSTT 1360

Query: 120  NIELVDTFQTLEPRASDAKNQEGKVNTRRKSTD------SVPISKSTL--SRSLSLQASD 171
             ++      T     S     EG        ++      S+P+S + +  S + +L A+ 
Sbjct: 1361 PVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATP 1420

Query: 172  FDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKET 231
             D  S+ G   A A +    + G S  +ST         PS  K      P    PV  +
Sbjct: 1421 VD-TSTPGTTSAEATSSPTTAEGISIPTST---------PSEGKTPLKSIPVSNTPVANS 1470

Query: 232  QQEPDEESLVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGV 291
            +      + V S   + + T   S+ T              PA G   A    SE +  +
Sbjct: 1471 EASTLSTTPVDSNSPVVTSTAVSSSPT--------------PAEGTSIAISTPSEGSTAL 1516

Query: 292  VPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDK 351
                     V +S      T P  T+     VT         + A G S++    YSE  
Sbjct: 1517 TSIPVSTTTVASSEINSLSTTPAVTSTP---VTTYSQASSSPTTADGTSMQTS-TYSEGS 1572

Query: 352  SSWDN----------QQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPA 401
            +   +           + N   T  I  K              T E    T ++P     
Sbjct: 1573 TPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASS-STTAEGSSMTISTPSEGSP 1631

Query: 402  EPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKT 461
                IP++             P  +  S+T     SP +     +  P   + +  P  T
Sbjct: 1632 LLTSIPVSTTPVA-------SPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTST 1684

Query: 462  --SSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSP 519
                +TP + S +  +  + +SA+         L+       TP+ T T   + SP  S 
Sbjct: 1685 YTEGRTPLT-SITVRTTPVASSAIST-------LSTTPVDNSTPVTTST-EARSSPTTSE 1735

Query: 520  LSDPPSQDPTPAATPETP-PVISAVVHATDEEKLAVTNQKWTCMTVDLEADKQDYPQPSD 578
             +  P+  P+   TP T  PV +  V +++   L+ T                    P D
Sbjct: 1736 GTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSAT--------------------PID 1775

Query: 579  LSTFVNETK--FSSPT--EELDYRNSYEIEYMEKIGSSLPQDDDAPKKQALYLMFD-TSQ 633
             ST V  +    SSPT  E      S   E M  + S+          +A  L       
Sbjct: 1776 TSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDS 1835

Query: 634  ESPVKSSPVRMSESPTPCSGSSFEETEALVNTAAKNQHPVPRGLAPNQESH 684
             SPV +S   +S SPTP  G+S   +     + A    PV      + E++
Sbjct: 1836 NSPVVTSTA-VSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETN 1885



 Score = 43.9 bits (102), Expect = 8e-04
 Identities = 150/760 (19%), Positives = 239/760 (31%), Gaps = 155/760 (20%)

Query: 24  SSDSEEAFETPESTTPVKAPPAPPPPP-PEVIPEPE--------VSTQPPPEEPGCGSET 74
           +SDS   F  P ST    +P  P     P   P  E        VST P P      S T
Sbjct: 122 TSDSTTLF--PSSTEDTSSPTTPEGTDVPMSTPSEESISSTMAFVSTAPLPSFEAYTSLT 179

Query: 75  VPV---------------PDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFD 119
             V               P  P S ++  S     S   +++      +ASS    L   
Sbjct: 180 YKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTT 239

Query: 120 NIELVDTFQTLEPRASDAKNQEG-KVNTRRKSTDSVPISKSTLSRSL--SLQASDF---- 172
            +E+          +S     EG  ++    S  S P+++  LS  L  S +AS      
Sbjct: 240 PVEISTPVTISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTP 299

Query: 173 -----------DGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKK 221
                      + +SS    E  ++    Y+ GS+  +ST   T       +     T  
Sbjct: 300 AATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSIT-- 357

Query: 222 PTETPPVKETQQEPDEESLVPSGENLASETKTE--------------------------- 254
           P +T  +  T  EP          ++ + T +E                           
Sbjct: 358 PVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIP 417

Query: 255 --------SAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPP 306
                   +A     SP   E+T +  +   + + PL S       P AS      ++ P
Sbjct: 418 VDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPV-STTPVASSEASNLSTTP 476

Query: 307 VGRKTLPLT-----TAPEAGEVT--PSDSGGQEDSPAKGLSV------------------ 341
           V  KT   T     ++P   EV   P+ +  +  +P   +SV                  
Sbjct: 477 VDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPV 536

Query: 342 --RLEFDYSEDKSSWDNQQEN---PPPTKKIGKKPVAKMPL-RRPKMKKTPEKLDNTP-- 393
                   S + SS     E    P  T   G  P+  MP+  R  +         TP  
Sbjct: 537 DTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPAD 596

Query: 394 ----------ASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQ 443
                     AS   + AE   +P    T T+        + +  ++     E+  L   
Sbjct: 597 SNTFVTTSSEASSSSTTAEGTSMP----TSTYSERGTTITSMSVSTTLVASSEASTLSTT 652

Query: 444 SYNFD-PDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEAN-----GVDGDGLNKPA 497
             + + P T         T+++  S P+ +      P ++M  N       +   L+   
Sbjct: 653 PVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTP 712

Query: 498 KKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETP-PVISAVVHATDEEKLAVTN 556
               TP+ T T     SP  +  +  P+  P+  +TP T  PV   ++ +++   L+ T 
Sbjct: 713 VDTSTPVTTST-EASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTP 771

Query: 557 -QKWTCMTVDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQ 615
               T +T   EA        S  +T       S+P+E      S  +            
Sbjct: 772 LDTSTHITTSTEA------SCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEAST 825

Query: 616 DDDAPKKQALYLMFDTSQESPVKSSPVRMSESPTPCSGSS 655
               P              SPV +S   +S SPTP  G+S
Sbjct: 826 LSTTP----------VDSNSPVTTS-TEVSSSPTPAEGTS 854


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 60.5 bits (145), Expect = 8e-09
 Identities = 118/536 (22%), Positives = 184/536 (34%), Gaps = 92/536 (17%)

Query: 30  AFETPESTTP---VKAPPAPPPPPPEVIPEP--------EVSTQPPPEEP-GCGSETVPV 77
           A  TP +  P      PP  P PPP V P           V  +P  E   G G  T+P 
Sbjct: 13  AARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP- 71

Query: 78  PDGPRSDSVE--GSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRAS 135
              PR+      G+  R P+           P +  G       N              +
Sbjct: 72  ESAPRAGPTRSAGTSSRNPA--------SRPPASGRGERAPPAKNTSPGPVSSPGRASGT 123

Query: 136 DAKNQEGKVNTRRKSTDSVPISKSTLS---RSLSLQASDFDGASSSGNPEAVALAPDAYS 192
                 G+   R  + ++V   K+T +    +LS  A       + G P + A+A  + +
Sbjct: 124 TRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTP-SPAMARRSRA 182

Query: 193 TGSSSASSTLKRTKKPRPPSLKKKQTTKKPTE---TPPVKETQQEPDEESLV--PSGENL 247
            G+         + +PRPP+   +++    +E   T P    ++ P     +  P+  +L
Sbjct: 183 AGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL 242

Query: 248 ASE-TKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPP 306
           +S  T   S    GPS       P  P+  PK       +  + + PP     R   +P 
Sbjct: 243 SSSATPLSSPARSGPSARGTPRAPAHPS-QPK------PKGLQALRPPQVTPPRKDAAPA 295

Query: 307 VGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKK 366
           +G    PL+++P A   TPS S   +      L                      P +  
Sbjct: 296 LG----PLSSSPLA---TPSPSAALQSQAPPTLPA-------------------TPHSSS 329

Query: 367 IGKKPVAKMPLRRPKMKKTP--EKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPN 424
           +  +    +PL  P     P  + L + PA+PP         P  + T++F       P 
Sbjct: 330 LTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSF----LPSPP 385

Query: 425 FNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAME 484
            +P  +T   Q  P L              ++ P +     P+SP  SP +   P +   
Sbjct: 386 LSPL-ATPPPQAPPAL--------------ALPPLQAPPSPPASPPLSPLATPSPQA--- 427

Query: 485 ANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATP--ETPP 538
            N +    L  P     +P     F    SP  SP + PPSQ P   A P  + PP
Sbjct: 428 PNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPP 483



 Score = 50.4 bits (119), Expect = 8e-06
 Identities = 98/413 (23%), Positives = 139/413 (33%), Gaps = 70/413 (16%)

Query: 146 TRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRT 205
           +   +T+  P ++   S    LQ       SSS  P    L+  A S    SA  T +  
Sbjct: 213 SEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP----LSSPARS--GPSARGTPRAP 266

Query: 206 KKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPAL 265
             P  P  K  Q  + P  TPP K+        S  P        T + SA  +  +P  
Sbjct: 267 AHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLA------TPSPSAALQSQAPPT 320

Query: 266 LEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTP 325
           L  TP   ++  + A PL       + PP+       ++PP       L T P      P
Sbjct: 321 LPATPHSSSLTCQLATPLP------LAPPSP------SAPP------SLQTLPSPPATPP 362

Query: 326 SDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKT 385
           S +     SP       L+  +S   S        PP +      P A   L  P ++  
Sbjct: 363 SQATTSLGSPT------LQATHSFLPS--------PPLSPLATPPPQAPPALALPPLQAP 408

Query: 386 PEKLDNTPASPPRSP-AEPN-DIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQ 443
           P    + PASPP SP A P+   P A   +      +  P   P  +      SP +   
Sbjct: 409 P----SPPASPPLSPLATPSPQAPNALAVHLLQAP-FSPPPSPPVQAPFSPPASPPVSPS 463

Query: 444 SYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTP 503
           +          +  P +     P+SP  SP++   P  A          L KP  +    
Sbjct: 464 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP-PPQAPPPLAAPPLQLAKPPPQAPPA 522

Query: 504 LKTDTFRVKKSPKRS----------------PLSDPPSQDPTPAATP--ETPP 538
           L T   +   SP  S                PL+ PP Q P   A P  + PP
Sbjct: 523 LATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPP 575



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 94/424 (22%), Positives = 140/424 (33%), Gaps = 40/424 (9%)

Query: 132 PRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVA------ 185
           P A       G V  +  +  +  I  +T+  S           +SS NP +        
Sbjct: 41  PAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRG 100

Query: 186 -LAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSG 244
             AP A +T     SS  + +   RP  L +K       ET    +  + P   +L    
Sbjct: 101 ERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALS--- 157

Query: 245 ENLASETKTESAKTEG-PSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQN 303
              A   +  S  T G PSPA+   +    A G +   P  + SA    PP  G  +  +
Sbjct: 158 ---AGARRDTSGPTPGTPSPAMARRSR---AAGTEVGLPRPAPSARPR-PPTEGPRKSVS 210

Query: 304 SPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPP 363
           S      T P   A       PS  GG +   ++ LS       S  +S    +     P
Sbjct: 211 SASEHSTTEPSPAARRR----PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAP 266

Query: 364 TKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTFDIDKWDDP 423
                 KP     LR P++  TP + D  PA  P S +     P+A  + +  +     P
Sbjct: 267 AHPSQPKPKGLQALRPPQV--TPPRKDAAPALGPLSSS-----PLATPSPSAALQSQAPP 319

Query: 424 NF--NPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPAS 481
                P SS+   Q +  LP             S     +    PS P+  P+       
Sbjct: 320 TLPATPHSSSLTCQLATPLP---------LAPPSPSAPPSLQTLPSPPATPPSQATTSLG 370

Query: 482 AMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAATPETPPVIS 541
           +           + P     TP       +   P ++P S P S   +P ATP      +
Sbjct: 371 SPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNA 430

Query: 542 AVVH 545
             VH
Sbjct: 431 LAVH 434



 Score = 40.0 bits (92), Expect = 0.011
 Identities = 72/335 (21%), Positives = 108/335 (32%), Gaps = 39/335 (11%)

Query: 1   MGGSQSLQPAPASDLNLEASEAMSSDSEEAFETPESTTPVKAPPAPPPPPP--EVIPEPE 58
           +  S    P+P++ L  +A   + +    +  T +  TP+   P  P  PP  + +P P 
Sbjct: 299 LSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPP 358

Query: 59  VSTQPPPEEPGCGSETVP-----VPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGT 113
            +T P       GS T+      +P  P S      P  PP+ +   +     P AS   
Sbjct: 359 -ATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPL 417

Query: 114 YNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFD 173
             L   + +  +       +A  +      V        S P+S S    S +       
Sbjct: 418 SPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQA------- 470

Query: 174 GASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKET-- 231
             S +  P  V  +P A    S SA+      + P P +    Q  K P + PP   T  
Sbjct: 471 PPSLAAPPLQVPPSPPASPPMSPSATPP---PQAPPPLAAPPLQLAKPPPQAPPALATPP 527

Query: 232 -QQEPDEESLVPSGENLASETKTESAKTEGPSP-------ALLEETPLEPAVGPKAACPL 283
            Q  P   +  P     +       +    P P       A L + P  P   P    P 
Sbjct: 528 LQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPR 587

Query: 284 DSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAP 318
                    PP  G     + P   R TL L   P
Sbjct: 588 R--------PPTPGPDTSVSGP---RLTLALAPGP 611



 Score = 38.9 bits (89), Expect = 0.025
 Identities = 64/294 (21%), Positives = 105/294 (35%), Gaps = 41/294 (13%)

Query: 10  APASDLNLEASEAMSSDSEEAFETPESTTPVKAPPAPPP--PPPEVIPEPEVSTQPPPEE 67
           +P++    +A  ++++   +   +P ++ P+     PPP  PPP   P  +++  PP   
Sbjct: 461 SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAP 520

Query: 68  PGCGSETVPVPDGPRSDSVEGSPFRP----PSHSFSAVFDEDKPIASSGTYNLDFDNIEL 123
           P   +  +     P +     +PF P    P    +    +  P+ ++    +   +   
Sbjct: 521 PALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVP-PSPPA 579

Query: 124 VDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLS--LQASDFDGASSSGN- 180
             T Q   PR       +  V+  R +    P      SRS S  L   D  G SSS   
Sbjct: 580 SPTLQA--PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATS 637

Query: 181 -----------PEAVALA---PDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETP 226
                      PE  A A   PDA       A+ +    + P PP L  +     P   P
Sbjct: 638 TPEELRGYDSGPEGGAAASPPPDAELAACHPAAWS----RGPAPP-LAFRGAPGAPLPWP 692

Query: 227 PVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAA 280
           P               S + L +  +TE  ++  P+P  L+  P     G KAA
Sbjct: 693 PATGPG----------SADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAA 736



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 78/331 (23%), Positives = 117/331 (35%), Gaps = 62/331 (18%)

Query: 3   GSQSLQPAPASDLNLEASEAMS--SDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVS 60
           G Q+L+P   +    +A+ A+   S S  A  +P +    +APP  P  P       +++
Sbjct: 276 GLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLA 335

Query: 61  TQPPPEEPGCGSETVPVPDGPRS-DSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFD 119
           T P P  P       P P  P S  ++   P  PPS +               T +L   
Sbjct: 336 T-PLPLAP-------PSPSAPPSLQTLPSPPATPPSQA---------------TTSLGSP 372

Query: 120 NIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSL-SLQASDFDGASSS 178
            ++   +F    P                 S  + P  ++  + +L  LQA     AS  
Sbjct: 373 TLQATHSFLPSPP----------------LSPLATPPPQAPPALALPPLQAPPSPPASPP 416

Query: 179 GNPEAV--ALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPD 236
            +P A     AP+A +     A  +        PP     Q    P  +PPV  +   P 
Sbjct: 417 LSPLATPSPQAPNALAVHLLQAPFS--------PPPSPPVQAPFSPPASPPVSPSATPPS 468

Query: 237 EESLVPSGENL-------ASETKTESAKTEGPSPALLEETPLEPAVGPKAACP-LDSESA 288
           +     +   L       AS   + SA     +P  L   PL+ A  P  A P L +   
Sbjct: 469 QAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPL 528

Query: 289 EGV-VPPASGGGRVQNSPPVGRKTLPLTTAP 318
           + +  PPAS  G+   SP       PL T P
Sbjct: 529 QALPSPPASFPGQAPFSPSASLPMSPLATPP 559


>gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]
          Length = 1233

 Score = 60.5 bits (145), Expect = 8e-09
 Identities = 53/199 (26%), Positives = 97/199 (48%), Gaps = 15/199 (7%)

Query: 835  EIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREK-SVSHQTVQQLV 893
            E+ +K +E+ + K + ++   E+ E +K + +  +   Q IE E +EK S  +Q   Q +
Sbjct: 241  ELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMRE-QQQIEKEIKEKDSELNQKRPQYI 299

Query: 894  LEKEQA---LADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQ 950
              KE     +  L + +KSL +  + Y+K K  ++   K    +++  QE+  R+++E Q
Sbjct: 300  KAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERMEEESQ 359

Query: 951  RY---------QALKVHA-EEKLDRANAEIAQVRGKAQQEQAAHQASLRKEQLRVDALER 1000
                       Q  K H  +E+  +  A +AQ   K  ++Q A Q  L  E+ +    E 
Sbjct: 360  SQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEA 419

Query: 1001 TLEQKNKEIEELTKICDEL 1019
             ++QK +EIEE  K  ++L
Sbjct: 420  KIKQKLREIEENQKRIEKL 438



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 45/199 (22%), Positives = 90/199 (45%), Gaps = 18/199 (9%)

Query: 842  EVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQALA 901
            ++ E K++  E  +E M+ ++  AE  +  +Q    + R K       Q         L 
Sbjct: 673  KLKEKKERLTEELKEQMKAKRKEAELRQVQSQAHGLQMRLKYSQSDLEQTKTRHLALNLQ 732

Query: 902  DLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKE---EQRYQALKVH 958
            + + +E  LA+   R   +K +++   +  + LK    +    V +E   E   + ++  
Sbjct: 733  EKSKLESELANFGPRINDIKRIIQSREREMKDLKEKMNQVEDEVFEEFCREIGVRNIREF 792

Query: 959  AEEKLDRANAEIAQVRGKAQQEQAA-------HQASLRKEQLRVDALERTLEQKNKEIEE 1011
             EEK+ R N EIA+ R + + ++          +  L+++Q +V   E+T+++   EIE+
Sbjct: 793  EEEKVKRQN-EIAKKRLEFENQKTRLGIQLDFEKNQLKEDQDKVHMWEQTVKKDENEIEK 851

Query: 1012 L-------TKICDELIAKM 1023
            L        KI DE +A++
Sbjct: 852  LKKEEQRHMKIIDETMAQL 870



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 43/206 (20%), Positives = 90/206 (43%), Gaps = 29/206 (14%)

Query: 829  LQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQT 888
            L+ A+  +   ++   + K   +E  +E++ + K   E+E+ + +  + + R+ ++    
Sbjct: 312  LEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQ 371

Query: 889  VQQLVLEKEQA----------LADLNSVEKSLADLFRRYEKMK-----EVLEGFRKNEEV 933
            V++    KE+A          L   N  +K+  D     E+ K     ++ +  R+ EE 
Sbjct: 372  VKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKLREIEEN 431

Query: 934  LKRC--AQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQEQAAHQASLRKE 991
             KR    +EY++  K+  +  + L+    E+++ A   I ++  +  Q           E
Sbjct: 432  QKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKELNQVM---------E 482

Query: 992  QL---RVDALERTLEQKNKEIEELTK 1014
            QL   R+D  E + +Q+  EI E  K
Sbjct: 483  QLGDARIDRQESSRQQRKAEIMESIK 508



 Score = 40.8 bits (94), Expect = 0.007
 Identities = 62/279 (22%), Positives = 121/279 (43%), Gaps = 40/279 (14%)

Query: 754  QKLQEELEFAIMRIEALKLARQIA----LASRSHQDAKREAAHPTDVSISKTALYSRIGT 809
            ++L EEL+      E +K  R+ A    + S++H    R     +D+  +KT    R   
Sbjct: 679  ERLTEELK------EQMKAKRKEAELRQVQSQAHGLQMRLKYSQSDLEQTKT----RHLA 728

Query: 810  AEVEKPAGLLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVME-------MRK 862
              +++ + L  +  +    +   +  I ++ERE+ + K+K  +   EV E       +R 
Sbjct: 729  LNLQEKSKLESELANFGPRINDIKRIIQSREREMKDLKEKMNQVEDEVFEEFCREIGVRN 788

Query: 863  IVAEYEKTIAQMIEDEQREKSVSHQTVQ---QLVLEKEQALADLNSVEKSLADLFRRYEK 919
            I    E+ + +  E  ++     +Q  +   QL  EK Q   D + V        +  +K
Sbjct: 789  IREFEEEKVKRQNEIAKKRLEFENQKTRLGIQLDFEKNQLKEDQDKVHM----WEQTVKK 844

Query: 920  MKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGK--A 977
             +  +E  +K E+   +   E +++++  + ++ A K    +K    N E+ ++R K   
Sbjct: 845  DENEIEKLKKEEQRHMKIIDETMAQLQDLKNQHLAKKSEVNDK----NHEMEEIRKKLGG 900

Query: 978  QQEQAAHQASLRKEQLRVDALERTLEQKNKEIEELTKIC 1016
              ++  H   L+KE   V A+E  LEQK  +   L + C
Sbjct: 901  ANKEMTH---LQKE---VTAIETKLEQKRSDRHNLLQAC 933



 Score = 37.0 bits (84), Expect = 0.095
 Identities = 44/205 (21%), Positives = 87/205 (42%), Gaps = 13/205 (6%)

Query: 826  DSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSV- 884
            DS L   R + I  +   S    K E +++ +   +K    Y+K    M E E+   SV 
Sbjct: 288  DSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQK---HYKKRKGDMDELEKEMLSVE 344

Query: 885  -SHQTVQQLVLEKEQALA-DLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYL 942
             + Q  ++ + E+ Q+   DL   E  +    R  E+  +      +  E   R  +   
Sbjct: 345  KARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQ 404

Query: 943  SRVKKEEQRYQALKVHAEEKLDRANAEIAQVR---GKAQQEQAAHQASLRKEQLRVDALE 999
             R+  EE++    KV  E K+ +   EI + +    K ++     + SL +++     L 
Sbjct: 405  DRLDLEERK----KVETEAKIKQKLREIEENQKRIEKLEEYITTSKQSLEEQKKLEGELT 460

Query: 1000 RTLEQKNKEIEELTKICDELIAKMG 1024
              +E   + I+E+ K  ++++ ++G
Sbjct: 461  EEVEMAKRRIDEINKELNQVMEQLG 485



 Score = 34.3 bits (77), Expect = 0.62
 Identities = 38/160 (23%), Positives = 72/160 (45%), Gaps = 11/160 (6%)

Query: 866  EYEKTIAQM-IEDEQREKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFRRYEKMKEVL 924
            EY + + ++ I  + R   V    V+ + ++  +    L        +L + Y+K K+ +
Sbjct: 116  EYSEELEKLGILIKARNFLVFQGAVESIAMKNPKERTALFEEISRSGELAQEYDKRKKEM 175

Query: 925  ----EGFRKNEEVLKRCAQEY--LSRVKKEEQRYQALK---VHAEEKLDRANAEIAQVR- 974
                E  + N    K  A E     + K+E  RYQ LK   V A+ +L        +V  
Sbjct: 176  VKAEEDTQFNYHRKKNIAAERKEAKQEKEEADRYQRLKDEVVRAQVQLQLFKLYHNEVEI 235

Query: 975  GKAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEELTK 1014
             K  +E A+    + K++ R+D +E  L++K KE+ ++ +
Sbjct: 236  EKLNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMR 275



 Score = 30.4 bits (67), Expect = 8.9
 Identities = 46/178 (25%), Positives = 76/178 (42%), Gaps = 25/178 (14%)

Query: 868  EKTIAQMIEDEQREKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFRRYE----KMKEV 923
            ++T A++I     E  ++++ VQ  + E  + L  L  + K+   L  +       MK  
Sbjct: 91   DRTFARVIVGGSSEYKINNKVVQ--LHEYSEELEKLGILIKARNFLVFQGAVESIAMKNP 148

Query: 924  LEGFRKNEEVLK--RCAQEYLSR----VKKEEQR----YQALKVHAEEKLDRANAEIAQV 973
             E     EE+ +    AQEY  R    VK EE      ++   + AE K  +   E A  
Sbjct: 149  KERTALFEEISRSGELAQEYDKRKKEMVKAEEDTQFNYHRKKNIAAERKEAKQEKEEADR 208

Query: 974  RGKAQQEQAAHQASLR-----KEQLRVDALERTLEQKNKEIEE----LTKICDELIAK 1022
              + + E    Q  L+       ++ ++ L + L  KNKEIE+    + K+ DEL  K
Sbjct: 209  YQRLKDEVVRAQVQLQLFKLYHNEVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEK 266


>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
          Length = 1427

 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 84/336 (25%), Positives = 118/336 (35%), Gaps = 40/336 (11%)

Query: 11   PASDLNLEASEAMSSDSEEAFETPES-TTPVKA--PPAPPPPPPEVIPEPEVSTQ----- 62
            PAS      +    +    A  TPE  T+P  A  PP  P  P   +P PE  T      
Sbjct: 1000 PASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAV 1059

Query: 63   PPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIE 122
            P PEEP   +  VP P+ P S +        P+   +AV   ++P + +       +   
Sbjct: 1060 PTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPAS 1119

Query: 123  LVDTFQTLEPRASDAKNQEGKVNTRRK---STDSVPISKSTLSRSLSLQASDFDGASSSG 179
                  T E  AS A      V T  +      +VP  + + S ++++   +      S 
Sbjct: 1120 PAAAVPTPEEPASPA----AAVPTPEEPAFPAPAVPTPEESASAAVAVPTPE-----ESA 1170

Query: 180  NPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEES 239
            +P A    P A S   ++  +TL+    P             PT    V   ++     +
Sbjct: 1171 SPAAAVPTP-AESASFAAVVATLEEPTSP---------AASVPTPAAMVATLEEFTSPAA 1220

Query: 240  LVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAA-CPLDSESAEGVVP----P 294
             VP+ E  AS     S   E  SPA    T  EP     A   P +  S    VP    P
Sbjct: 1221 SVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEP 1280

Query: 295  ASGGGRVQN-----SPPVGRKTLPLTTAPEAGEVTP 325
            AS    V N     SP     T  +   P A   TP
Sbjct: 1281 ASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTP 1316



 Score = 57.4 bits (137), Expect = 7e-08
 Identities = 94/416 (22%), Positives = 140/416 (33%), Gaps = 63/416 (15%)

Query: 33   TPES-TTPVKAPPAPPPP--PPEVIPEPEVSTQP-----PPEEPGCGSETVPVPDGPRSD 84
            TPE   +P  A P P  P  P   +P PE  T P     PPEEP   +  VP P+ P S 
Sbjct: 996  TPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSP 1055

Query: 85   SVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKV 144
            +        P+   +AV   ++P + +            V T +  EP +  A     + 
Sbjct: 1056 AAAVPTPEEPTSPAAAVPTPEEPTSPAAA----------VPTPE--EPTSPAAAVPTPEE 1103

Query: 145  NTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKR 204
             T   +    P   ++ + ++         A++   PE  A    A  T   SAS+ +  
Sbjct: 1104 PTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAV-- 1161

Query: 205  TKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPA 264
                                  P  E    P   + VP+    AS     +   E  SPA
Sbjct: 1162 --------------------AVPTPEESASP--AAAVPTPAESASFAAVVATLEEPTSPA 1199

Query: 265  LLEETP------LEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAP 318
                TP      LE    P A+ P   E A   +  A        SP     TL   T+ 
Sbjct: 1200 ASVPTPAAMVATLEEFTSPAASVPTSEEPAS--LAAAVSNPEEPTSPAAAVPTLEEPTSS 1257

Query: 319  EAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLR 378
             A  +TP      E+  +   SV    + +   ++  N +E   P   +    VA +P  
Sbjct: 1258 AAAVLTP------EELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAA 1311

Query: 379  RPKMKKTPEKLDNTPASPPRSPAEPNDIP---IAKGTYTFDIDKWDDPNFNPFSST 431
                 + P       A PP     P  +P   ++  T +  I +   P     SST
Sbjct: 1312 SVPTPEVP--AIPAAAVPPMEEVSPIGVPFLGVSAHTDSVPISEEGTPVLEEASST 1365



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 92/409 (22%), Positives = 140/409 (34%), Gaps = 76/409 (18%)

Query: 9    PAPASDLNLEASEAMSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEP 68
            PA A+ +  E   A++  S E +     T P+      P  P  V P    +T   PEEP
Sbjct: 934  PAVAAAITQEGMSAVAGFSPE-WAALAITVPITEEDGTPEGP--VTP---ATTVHAPEEP 987

Query: 69   GCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQ 128
               +  V  P+ P S +        P+   +AV   ++P + +                 
Sbjct: 988  DTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAV-------------- 1033

Query: 129  TLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAP 188
               P   +  +    V T  + T                            +P A    P
Sbjct: 1034 ---PPPEEPTSPAAAVPTPEEPT----------------------------SPAAAVPTP 1062

Query: 189  DAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEP-DEESLVPSGENL 247
            +      +S ++ +   ++P  P+     T ++PT       T +EP    + VP+ E  
Sbjct: 1063 EE----PTSPAAAVPTPEEPTSPA-AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEP 1117

Query: 248  ASETKTESAKTEGPSPALLEETPLEPAV-GPKAACPLDSESAEGVVPPASGGGRVQNSPP 306
            AS         E  SPA    TP EPA   P    P +S SA   VP        +++ P
Sbjct: 1118 ASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPE-----ESASP 1172

Query: 307  VGRKTLPLTTAPEAGEVT----PSDSGGQEDSPAKGLSVRLEF-------DYSEDKSSWD 355
                  P  +A  A  V     P+       +PA  ++   EF         SE+ +S  
Sbjct: 1173 AAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLA 1232

Query: 356  NQQENP-PPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEP 403
                NP  PT      P  + P        TPE+L +  AS P +P EP
Sbjct: 1233 AAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVP-TPEEP 1280



 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 88/400 (22%), Positives = 145/400 (36%), Gaps = 50/400 (12%)

Query: 180  NPEAVALA-------PDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQ 232
            +PE  ALA        D    G  + ++T+   ++P   +++   T ++P        T 
Sbjct: 952  SPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVS-TPEEPASPAAAVPTP 1010

Query: 233  QEPDEESL-VPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSE--SAE 289
            +EP   +  VP+ E   S         E  SPA    TP EP   P AA P   E  S  
Sbjct: 1011 EEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEP-TSPAAAVPTPEEPTSPA 1069

Query: 290  GVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSE 349
              VP          SP     T    T+P A   TP      E+  +   +V    + + 
Sbjct: 1070 AAVPTP----EEPTSPAAAVPTPEEPTSPAAAVPTP------EEPTSPAAAVPTPEEPAS 1119

Query: 350  DKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPP-----RSPAEPN 404
              ++    +E   P   +   P  + P        TPE+  +   + P      SPA   
Sbjct: 1120 PAAAVPTPEEPASPAAAV---PTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAV 1176

Query: 405  DIPIAKGTYTFDIDKWDDPNF------NPFSSTSKMQESPKLPQQSYNFDPDTCDESVDP 458
              P    ++   +   ++P         P +  + ++E    P  S     +    S+  
Sbjct: 1177 PTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTS-PAASVPTSEEPA--SLAA 1233

Query: 459  FKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRS 518
              ++ + P+SP+ +  + E P S+  A  +  + L+ PA    TP +  +     S    
Sbjct: 1234 AVSNPEEPTSPAAAVPTLEEPTSSAAA-VLTPEELSSPAASVPTPEEPASPAAAVSNLEE 1292

Query: 519  PLSDPPSQDPTP---------AATPETPPVISAVVHATDE 549
            P S P +  PTP           TPE P + +A V   +E
Sbjct: 1293 PAS-PAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPMEE 1331


>gi|58530840 desmoplakin isoform I [Homo sapiens]
          Length = 2871

 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 60/276 (21%), Positives = 116/276 (42%), Gaps = 39/276 (14%)

Query: 768  EALKLARQIALASRSHQDAKREAAHPTDVSISKTALYSRI----------GTAEVEKPAG 817
            ++  L  Q+   SR ++D K E     D  +  T    R           G+  ++K   
Sbjct: 1231 DSKNLRNQLDRLSRENRDLKDEIVRLNDSILQATEQRRRAEENALQQKACGSEIMQKKQH 1290

Query: 818  L------LFQQPDLDSA-----LQIARAEIITKEREVSEWKDKYEESRREVME----MRK 862
            L      + QQ   D+A     L+ A   I  K +E+   K +++E  +   E    + K
Sbjct: 1291 LEIELKQVMQQRSEDNARHKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELSK 1350

Query: 863  IVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFRRYEKMKE 922
            +   Y++ I  +    + E +++  T+ QL ++KE+   D +     + +L R    + E
Sbjct: 1351 VRNNYDEEIISLKNQFETEINITKTTIHQLTMQKEE---DTSGYRAQIDNLTRENRSLSE 1407

Query: 923  VLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQEQA 982
             ++  +           E L RV+++ Q+ +A      ++  +   E+ QV     +E  
Sbjct: 1408 EIKRLKNTLTQ----TTENLRRVEEDIQQQKATGSEVSQRKQQLEVELRQVTQMRTEESV 1463

Query: 983  AHQASLRKEQLRVDALERTLEQKNKEIEELTKICDE 1018
             ++ SL       D   +T++ KNKEIE L ++ D+
Sbjct: 1464 RYKQSL-------DDAAKTIQDKNKEIERLKQLIDK 1492



 Score = 51.2 bits (121), Expect = 5e-06
 Identities = 53/216 (24%), Positives = 107/216 (49%), Gaps = 24/216 (11%)

Query: 824  DLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKS 883
            D ++ LQ  + ++       +E  +K +   +E+  +R    +YE+ ++Q    + ++ +
Sbjct: 1502 DENARLQRVQYDLQKANSSATETINKLKVQEQELTRLR---IDYER-VSQERTVKDQDIT 1557

Query: 884  VSHQTVQQLVLEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKN--EEVLK----RC 937
                ++++L L+K++   +LN ++++ ++   + +K++E LEG R++  E+ +K      
Sbjct: 1558 RFQNSLKELQLQKQKVEEELNRLKRTASEDSCKRKKLEEELEGMRRSLKEQAIKITNLTQ 1617

Query: 938  AQEYLSRVKKE-----EQRYQALKVHAEEK------LDRANAEIAQVRGKAQQEQ-AAHQ 985
              E  S VKK       Q+   L  H  EK      L R ++E+  +R +  QEQ +  Q
Sbjct: 1618 QLEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSSEVEALRRQLLQEQESVKQ 1677

Query: 986  ASLRKE--QLRVDALERTLEQKNKEIEELTKICDEL 1019
            A LR E  Q  ++   R+L +   EIE L  + + L
Sbjct: 1678 AHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENL 1713



 Score = 39.3 bits (90), Expect = 0.019
 Identities = 58/257 (22%), Positives = 107/257 (41%), Gaps = 37/257 (14%)

Query: 751  LFAQKLQEELEFAIMRIEALKLARQIALASRSHQDAKREAAHPTDVSISKTALYSRIGTA 810
            L  + L  E E   +R+E   L R      RS  D+ + A   T + +      S   T 
Sbjct: 1713 LTKEHLMLEEELRNLRLEYDDLRR-----GRSEADSDKNA---TILELRSQLQISNNRTL 1764

Query: 811  EVEKPAGLLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESR---------REVMEMR 861
            E++   GL+    DL    +  R EI   +++  E  ++ +ES+         RE + ++
Sbjct: 1765 ELQ---GLI---NDLQRERENLRQEIEKFQKQALEASNRIQESKNQCTQVVQERESLLVK 1818

Query: 862  KIVAEYEKTIAQMIEDE-QREKSVSH---QTVQQLVLEKEQALADLNSVEKSLADLFRRY 917
              V E +K   Q +EDE  R KS      +  Q+L  EK+Q   DLN  +        +Y
Sbjct: 1819 IKVLEQDKARLQRLEDELNRAKSTLEAETRVKQRLECEKQQIQNDLNQWK-------TQY 1871

Query: 918  EKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKA 977
             + +E +       E  +R      S +++ +   + ++     KL+ +  E    + + 
Sbjct: 1872 SRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKRIEERCRRKLEDSTRE---TQSQL 1928

Query: 978  QQEQAAHQASLRKEQLR 994
            + E++ +Q  + K + R
Sbjct: 1929 ETERSRYQREIDKLRQR 1945


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 58.5 bits (140), Expect = 3e-08
 Identities = 125/609 (20%), Positives = 179/609 (29%), Gaps = 90/609 (14%)

Query: 9    PAPASDLNLEASEAMSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVS--TQPPPE 66
            P P S   L  +   S  +      P +TTP         PPP   P P +S  T PPP 
Sbjct: 1408 PPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPT 1467

Query: 67   EPGCGSETVP-----VPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNI 121
                   T P      P  P + +    P   PS   +       P AS+ T        
Sbjct: 1468 TTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPI---TPPASTTTLP------ 1518

Query: 122  ELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNP 181
                   T  P             T      + PI+  T + +L          ++   P
Sbjct: 1519 ------PTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTL-------PPTTTPSPP 1565

Query: 182  EAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLV 241
                  P   +T S   ++T      P PP++    TT  PT TP    T       +  
Sbjct: 1566 PTTTTTPPPTTTPSPPTTTT------PSPPTI--TTTTPPPTTTPSPPTTTTTTPPPTTT 1617

Query: 242  PSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRV 301
            PS       T   S  T  P+      TP  P        P  + S      P+      
Sbjct: 1618 PSPPTTTPITPPTSTTTLPPT-----TTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTT 1672

Query: 302  QNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENP 361
               PP    + P+TT P +   T   +     +P+  ++       +   S        P
Sbjct: 1673 TTPPPTTTPSSPITTTP-SPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTP 1731

Query: 362  PPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASP--------PRSPAEPND--IPIAKG 411
             PT      P   M    P    +P  L  TP  P        P S   P    +P+   
Sbjct: 1732 SPT-TTPSPPTTTMTTLPPTTTSSP--LTTTPLPPSITPPTFSPFSTTTPTTPCVPLCNW 1788

Query: 412  TYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFD------PD----------TCDES 455
            T   D  K   PNF+     +++      P  + N        PD           CD S
Sbjct: 1789 TGWLDSGK---PNFHKPGGDTELIGDVCGPGWAANISCRATMYPDVPIGQLGQTVVCDVS 1845

Query: 456  VDPF-KTSSKTPSS--PSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVK 512
            V    K   + P    P     ++EI     E        + +P     T + T T    
Sbjct: 1846 VGLICKNEDQKPGGVIPMAFCLNYEINVQCCEC-------VTQP-----TTMTTTTTENP 1893

Query: 513  KSPKRSPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTVDLEADKQD 572
              P  +P++   +  PTP  T    P  + +   T            T  T  +      
Sbjct: 1894 TPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 1953

Query: 573  YPQPSDLST 581
             P P+   T
Sbjct: 1954 TPTPTPTGT 1962



 Score = 53.9 bits (128), Expect = 8e-07
 Identities = 89/444 (20%), Positives = 134/444 (30%), Gaps = 67/444 (15%)

Query: 218  TTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGP 277
            T   PT TP    T       +  PS     + T T    T  PSP +   T   P   P
Sbjct: 1398 TPSPPTTTPSPPPTSTTTLPPTTTPSPP---TTTTTTPPPTTTPSPPITTTTTPPPTTTP 1454

Query: 278  KAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAK 337
                           PP S       +PP      P TT P     TPS       +P  
Sbjct: 1455 S--------------PPIS----TTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPP 1496

Query: 338  GLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPP 397
              +                   +PP T  I   P A      P    +P     T   P 
Sbjct: 1497 TTT------------------PSPPTTTPI--TPPASTTTLPPTTTPSPPTTTTTTPPPT 1536

Query: 398  RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVD 457
             +P+ P   PI   T T  +     P+  P ++T+    +   P  +    P T   +  
Sbjct: 1537 TTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTP 1596

Query: 458  PFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKR 517
            P  T+   P++ + +P                      P+    TP+   T      P  
Sbjct: 1597 PPTTTPSPPTTTTTTPPP-----------------TTTPSPPTTTPITPPTSTTTLPPTT 1639

Query: 518  SPLSDPPSQDPTPAATPETPPVISAVVHATDEEKLAVTNQKWTCMTVDLEADKQDYPQPS 577
            +P   P +    P  T  +PP  +     T    +  T       T          P  +
Sbjct: 1640 TPSPPPTTTTTPPPTTTPSPPTTT-----TPSPPITTTTTPPPTTTPSSPITTTPSPPTT 1694

Query: 578  DLSTFVNETKFSSP--TEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQALYLMFDTSQES 635
             ++T    T  SSP  T       +        + +  P    +P    +  +  T+  S
Sbjct: 1695 TMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSS 1754

Query: 636  PVKSSPVRMSESPTPCSGSSFEET 659
            P+ ++P  +  S TP + S F  T
Sbjct: 1755 PLTTTP--LPPSITPPTFSPFSTT 1776



 Score = 40.4 bits (93), Expect = 0.009
 Identities = 102/537 (18%), Positives = 169/537 (31%), Gaps = 56/537 (10%)

Query: 14   DLNLEASEAMSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSE 73
            ++N++  E ++  +     T E+ TP    P          P P   TQ P   P   + 
Sbjct: 1870 EINVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTT 1928

Query: 74   TV---PVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTL 130
            TV   P P G ++      P   P  + + V     P   +GT          + T  T+
Sbjct: 1929 TVTPTPTPTGTQT------PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTV 1976

Query: 131  EPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDA 190
             P  +    Q         +T   P    T +++           +++       + P  
Sbjct: 1977 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTP 2026

Query: 191  YSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASE 250
              TG+ + ++T   T     P+      T+ PT TP    T   P      P+G    + 
Sbjct: 2027 TPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTT 2082

Query: 251  TKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGR 309
            T   +  T  P+P     TP     G +        +   V P P   G +   + P+  
Sbjct: 2083 TPITTTTTVTPTP-----TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2133

Query: 310  KTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGK 369
             T    T    G  TP+ +     +                          P PT    +
Sbjct: 2134 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2193

Query: 370  KPVAKMPLRRPKMKKTPEKLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNP 427
             P          +  TP      TP + P  +       P   GT T        P   P
Sbjct: 2194 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTP 2245

Query: 428  FSSTSKMQESPK-LPQQSYNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEAN 486
             ++T+ +  +P     Q+    P T   +V P  T + T  +P+ +P +     +     
Sbjct: 2246 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTP 2304

Query: 487  GVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
                     P     T   T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 2305 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2361



 Score = 36.2 bits (82), Expect = 0.16
 Identities = 129/665 (19%), Positives = 203/665 (30%), Gaps = 78/665 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 3711 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 3758

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 3759 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3811

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 3812 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3861

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 3862 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 3912

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 3913 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3968

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 3969 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 4028

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 4029 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 4080

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 4081 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 4139

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPVISAVVHATDEEKLAVTNQKWT 560
             T T    ++P  +P++   +  PTP  T    P T P+ +                  T
Sbjct: 4140 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPT 4199

Query: 561  CMTVDLEADKQDYPQPSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAP 620
              +    A+      P + ST       SSP  E     S     +E   ++ P    AP
Sbjct: 4200 HTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAP 4259

Query: 621  KKQALYLMFDTSQESPVKSSPVRMSESP--TP----CSGSSFEETEALVNTAAKNQ-HPV 673
                      T+      S P   + SP  TP     +GSS   T + V T   +   P 
Sbjct: 4260 ---------TTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPT 4310

Query: 674  PRGLA 678
            P  L+
Sbjct: 4311 PTPLS 4315



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 1963 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 2010

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 2011 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2063

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 2064 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2113

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 2114 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 2164

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 2165 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2220

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 2221 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2280

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 2281 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 2332

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 2333 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2391

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 2392 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2430



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 1986 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 2033

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 2034 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2086

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 2087 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2136

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 2137 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 2187

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 2188 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2243

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 2244 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2303

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 2304 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 2355

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 2356 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2414

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 2415 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2453



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 2009 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 2056

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 2057 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2109

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 2110 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2159

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 2160 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 2210

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 2211 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2266

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 2267 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2326

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 2327 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 2378

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 2379 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2437

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 2438 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2476



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 2032 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 2079

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 2080 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2132

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 2133 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2182

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 2183 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 2233

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 2234 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2289

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 2290 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2349

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 2350 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 2401

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 2402 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2460

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 2461 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2499



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 2055 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 2102

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 2103 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2155

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 2156 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2205

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 2206 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 2256

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 2257 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2312

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 2313 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2372

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 2373 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 2424

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 2425 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2483

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 2484 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2522



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 2078 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 2125

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 2126 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2178

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 2179 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2228

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 2229 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 2279

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 2280 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2335

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 2336 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2395

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 2396 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 2447

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 2448 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2506

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 2507 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2545



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 2101 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 2148

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 2149 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2201

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 2202 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2251

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 2252 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 2302

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 2303 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2358

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 2359 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2418

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 2419 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 2470

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 2471 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2529

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 2530 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2568



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 2124 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 2171

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 2172 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2224

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 2225 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2274

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 2275 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 2325

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 2326 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2381

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 2382 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2441

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 2442 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 2493

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 2494 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2552

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 2553 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2591



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 2147 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 2194

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 2195 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2247

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 2248 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2297

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 2298 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 2348

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 2349 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2404

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 2405 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2464

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 2465 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 2516

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 2517 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2575

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 2576 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2614



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 2170 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 2217

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 2218 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2270

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 2271 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2320

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 2321 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 2371

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 2372 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2427

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 2428 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2487

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 2488 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 2539

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 2540 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2598

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 2599 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2637



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 2193 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 2240

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 2241 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2293

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 2294 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2343

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 2344 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 2394

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 2395 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2450

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 2451 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2510

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 2511 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 2562

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 2563 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2621

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 2622 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2660



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 2216 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 2263

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 2264 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2316

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 2317 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2366

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 2367 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 2417

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 2418 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2473

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 2474 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2533

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 2534 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 2585

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 2586 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2644

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 2645 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2683



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 2239 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 2286

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 2287 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2339

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 2340 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2389

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 2390 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 2440

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 2441 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2496

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 2497 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2556

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 2557 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 2608

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 2609 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2667

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 2668 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2706



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 2262 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 2309

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 2310 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2362

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 2363 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2412

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 2413 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 2463

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 2464 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2519

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 2520 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2579

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 2580 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 2631

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 2632 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2690

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 2691 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2729



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 2285 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 2332

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 2333 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2385

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 2386 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2435

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 2436 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 2486

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 2487 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2542

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 2543 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2602

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 2603 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 2654

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 2655 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2713

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 2714 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2752



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 2308 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 2355

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 2356 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2408

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 2409 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2458

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 2459 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 2509

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 2510 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2565

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 2566 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2625

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 2626 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 2677

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 2678 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2736

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 2737 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2775



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 2331 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 2378

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 2379 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2431

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 2432 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2481

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 2482 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 2532

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 2533 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2588

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 2589 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2648

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 2649 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 2700

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 2701 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2759

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 2760 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2798



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 2354 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 2401

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 2402 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2454

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 2455 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2504

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 2505 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 2555

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 2556 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2611

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 2612 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2671

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 2672 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 2723

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 2724 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2782

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 2783 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2821



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 2377 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 2424

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 2425 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2477

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 2478 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2527

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 2528 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 2578

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 2579 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2634

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 2635 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2694

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 2695 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 2746

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 2747 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2805

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 2806 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2844



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 2400 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 2447

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 2448 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2500

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 2501 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2550

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 2551 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 2601

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 2602 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2657

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 2658 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2717

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 2718 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 2769

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 2770 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2828

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 2829 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2867



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 2423 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 2470

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 2471 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2523

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 2524 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2573

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 2574 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 2624

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 2625 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2680

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 2681 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2740

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 2741 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 2792

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 2793 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2851

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 2852 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2890



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 2446 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 2493

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 2494 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2546

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 2547 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2596

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 2597 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 2647

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 2648 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2703

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 2704 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2763

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 2764 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 2815

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 2816 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2874

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 2875 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2913



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 2469 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 2516

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 2517 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2569

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 2570 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2619

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 2620 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 2670

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 2671 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2726

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 2727 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2786

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 2787 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 2838

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 2839 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2897

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 2898 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2936



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 2492 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 2539

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 2540 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2592

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 2593 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2642

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 2643 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 2693

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 2694 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2749

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 2750 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2809

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 2810 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 2861

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 2862 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2920

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 2921 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2959



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 2515 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 2562

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 2563 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2615

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 2616 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2665

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 2666 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 2716

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 2717 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2772

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 2773 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2832

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 2833 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 2884

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 2885 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2943

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 2944 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2982



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 2538 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 2585

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 2586 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2638

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 2639 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2688

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 2689 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 2739

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 2740 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2795

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 2796 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2855

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 2856 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 2907

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 2908 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2966

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 2967 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3005



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 2561 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 2608

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 2609 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2661

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 2662 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2711

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 2712 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 2762

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 2763 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2818

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 2819 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2878

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 2879 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 2930

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 2931 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2989

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 2990 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3028



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 2584 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 2631

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 2632 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2684

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 2685 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2734

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 2735 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 2785

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 2786 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2841

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 2842 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2901

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 2902 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 2953

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 2954 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3012

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 3013 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3051



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 2607 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 2654

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 2655 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2707

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 2708 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2757

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 2758 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 2808

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 2809 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2864

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 2865 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2924

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 2925 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 2976

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 2977 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3035

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 3036 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3074



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 2630 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 2677

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 2678 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2730

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 2731 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2780

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 2781 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 2831

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 2832 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2887

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 2888 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2947

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 2948 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 2999

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 3000 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3058

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 3059 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3097



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 2653 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 2700

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 2701 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2753

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 2754 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2803

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 2804 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 2854

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 2855 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2910

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 2911 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2970

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 2971 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 3022

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 3023 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3081

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 3082 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3120



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 2676 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 2723

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 2724 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2776

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 2777 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2826

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 2827 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 2877

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 2878 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2933

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 2934 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2993

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 2994 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 3045

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 3046 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3104

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 3105 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3143



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 2699 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 2746

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 2747 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2799

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 2800 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2849

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 2850 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 2900

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 2901 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2956

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 2957 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3016

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 3017 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 3068

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 3069 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3127

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 3128 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3166



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 2722 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 2769

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 2770 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2822

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 2823 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2872

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 2873 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 2923

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 2924 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2979

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 2980 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3039

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 3040 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 3091

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 3092 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3150

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 3151 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3189



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 2745 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 2792

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 2793 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2845

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 2846 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2895

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 2896 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 2946

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 2947 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3002

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 3003 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3062

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 3063 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 3114

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 3115 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3173

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 3174 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3212



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 2768 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 2815

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 2816 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2868

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 2869 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2918

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 2919 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 2969

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 2970 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3025

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 3026 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3085

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 3086 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 3137

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 3138 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3196

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 3197 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3235



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 2791 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 2838

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 2839 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2891

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 2892 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2941

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 2942 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 2992

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 2993 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3048

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 3049 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3108

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 3109 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 3160

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 3161 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3219

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 3220 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3258



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 2814 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 2861

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 2862 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2914

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 2915 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2964

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 2965 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 3015

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 3016 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3071

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 3072 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3131

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 3132 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 3183

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 3184 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3242

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 3243 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3281



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 2837 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 2884

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 2885 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2937

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 2938 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2987

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 2988 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 3038

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 3039 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3094

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 3095 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3154

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 3155 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 3206

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 3207 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3265

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 3266 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3304



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 2860 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 2907

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 2908 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2960

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 2961 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3010

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 3011 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 3061

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 3062 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3117

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 3118 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3177

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 3178 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 3229

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 3230 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3288

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 3289 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3327



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 2883 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 2930

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 2931 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2983

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 2984 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3033

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 3034 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 3084

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 3085 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3140

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 3141 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3200

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 3201 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 3252

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 3253 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3311

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 3312 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3350



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 2906 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 2953

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 2954 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3006

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 3007 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3056

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 3057 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 3107

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 3108 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3163

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 3164 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3223

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 3224 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 3275

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 3276 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3334

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 3335 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3373



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 2929 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 2976

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 2977 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3029

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 3030 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3079

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 3080 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 3130

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 3131 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3186

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 3187 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3246

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 3247 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 3298

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 3299 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3357

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 3358 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3396



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 2952 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 2999

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 3000 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3052

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 3053 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3102

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 3103 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 3153

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 3154 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3209

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 3210 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3269

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 3270 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 3321

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 3322 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3380

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 3381 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3419



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 2975 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 3022

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 3023 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3075

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 3076 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3125

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 3126 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 3176

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 3177 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3232

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 3233 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3292

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 3293 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 3344

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 3345 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3403

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 3404 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3442



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 2998 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 3045

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 3046 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3098

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 3099 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3148

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 3149 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 3199

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 3200 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3255

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 3256 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3315

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 3316 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 3367

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 3368 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3426

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 3427 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3465



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 3021 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 3068

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 3069 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3121

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 3122 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3171

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 3172 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 3222

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 3223 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3278

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 3279 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3338

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 3339 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 3390

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 3391 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3449

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 3450 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3488



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 3044 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 3091

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 3092 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3144

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 3145 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3194

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 3195 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 3245

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 3246 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3301

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 3302 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3361

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 3362 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 3413

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 3414 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3472

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 3473 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3511



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 3067 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 3114

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 3115 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3167

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 3168 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3217

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 3218 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 3268

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 3269 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3324

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 3325 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3384

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 3385 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 3436

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 3437 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3495

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 3496 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3534



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 3090 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 3137

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 3138 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3190

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 3191 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3240

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 3241 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 3291

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 3292 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3347

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 3348 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3407

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 3408 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 3459

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 3460 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3518

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 3519 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3557



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 3113 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 3160

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 3161 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3213

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 3214 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3263

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 3264 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 3314

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 3315 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3370

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 3371 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3430

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 3431 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 3482

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 3483 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3541

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 3542 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3580



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 3136 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 3183

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 3184 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3236

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 3237 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3286

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 3287 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 3337

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 3338 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3393

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 3394 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3453

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 3454 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 3505

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 3506 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3564

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 3565 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3603



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 3159 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 3206

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 3207 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3259

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 3260 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3309

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 3310 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 3360

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 3361 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3416

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 3417 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3476

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 3477 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 3528

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 3529 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3587

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 3588 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3626



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 3182 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 3229

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 3230 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3282

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 3283 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3332

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 3333 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 3383

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 3384 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3439

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 3440 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3499

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 3500 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 3551

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 3552 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3610

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 3611 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3649



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 3205 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 3252

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 3253 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3305

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 3306 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3355

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 3356 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 3406

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 3407 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3462

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 3463 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3522

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 3523 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 3574

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 3575 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3633

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 3634 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3672



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 3228 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 3275

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 3276 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3328

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 3329 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3378

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 3379 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 3429

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 3430 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3485

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 3486 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3545

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 3546 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 3597

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 3598 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3656

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 3657 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3695



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 3251 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 3298

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 3299 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3351

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 3352 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3401

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 3402 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 3452

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 3453 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3508

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 3509 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3568

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 3569 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 3620

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 3621 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3679

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 3680 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3718



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 3274 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 3321

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 3322 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3374

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 3375 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3424

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 3425 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 3475

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 3476 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3531

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 3532 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3591

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 3592 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 3643

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 3644 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3702

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 3703 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3741



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 3297 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 3344

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 3345 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3397

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 3398 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3447

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 3448 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 3498

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 3499 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3554

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 3555 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3614

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 3615 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 3666

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 3667 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3725

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 3726 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3764



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 3320 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 3367

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 3368 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3420

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 3421 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3470

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 3471 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 3521

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 3522 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3577

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 3578 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3637

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 3638 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 3689

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 3690 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3748

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 3749 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3787



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 3343 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 3390

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 3391 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3443

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 3444 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3493

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 3494 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 3544

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 3545 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3600

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 3601 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3660

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 3661 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 3712

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 3713 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3771

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 3772 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3810



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 3366 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 3413

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 3414 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3466

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 3467 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3516

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 3517 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 3567

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 3568 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3623

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 3624 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3683

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 3684 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 3735

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 3736 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3794

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 3795 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3833



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 3389 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 3436

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 3437 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3489

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 3490 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3539

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 3540 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 3590

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 3591 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3646

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 3647 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3706

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 3707 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 3758

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 3759 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3817

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 3818 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3856



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 3412 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 3459

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 3460 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3512

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 3513 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3562

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 3563 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 3613

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 3614 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3669

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 3670 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3729

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 3730 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 3781

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 3782 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3840

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 3841 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3879



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 3435 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 3482

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 3483 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3535

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 3536 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3585

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 3586 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 3636

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 3637 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3692

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 3693 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3752

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 3753 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 3804

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 3805 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3863

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 3864 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3902



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 3458 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 3505

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 3506 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3558

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 3559 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3608

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 3609 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 3659

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 3660 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3715

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 3716 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3775

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 3776 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 3827

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 3828 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3886

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 3887 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3925



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 3481 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 3528

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 3529 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3581

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 3582 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3631

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 3632 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 3682

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 3683 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3738

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 3739 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3798

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 3799 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 3850

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 3851 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3909

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 3910 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3948



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 3504 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 3551

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 3552 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3604

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 3605 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3654

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 3655 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 3705

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 3706 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3761

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 3762 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3821

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 3822 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 3873

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 3874 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3932

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 3933 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3971



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 3527 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 3574

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 3575 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3627

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 3628 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3677

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 3678 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 3728

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 3729 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3784

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 3785 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3844

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 3845 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 3896

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 3897 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3955

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 3956 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3994



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 3550 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 3597

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 3598 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3650

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 3651 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3700

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 3701 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 3751

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 3752 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3807

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 3808 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3867

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 3868 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 3919

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 3920 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3978

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 3979 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4017



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 3573 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 3620

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 3621 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3673

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 3674 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3723

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 3724 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 3774

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 3775 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3830

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 3831 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3890

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 3891 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 3942

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 3943 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 4001

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 4002 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4040



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 3596 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 3643

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 3644 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3696

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 3697 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3746

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 3747 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 3797

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 3798 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3853

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 3854 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3913

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 3914 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 3965

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 3966 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 4024

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 4025 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4063



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 3619 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 3666

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 3667 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3719

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 3720 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3769

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 3770 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 3820

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 3821 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3876

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 3877 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3936

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 3937 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 3988

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 3989 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 4047

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 4048 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4086



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 3642 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 3689

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 3690 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3742

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 3743 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3792

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 3793 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 3843

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 3844 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3899

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 3900 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3959

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 3960 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 4011

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 4012 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 4070

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 4071 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4109



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 3665 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 3712

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 3713 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3765

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 3766 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3815

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 3816 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 3866

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 3867 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3922

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 3923 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3982

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 3983 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 4034

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 4035 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 4093

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 4094 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4132



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 99/519 (19%), Positives = 160/519 (30%), Gaps = 62/519 (11%)

Query: 32   ETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETV---PVPDGPRSDSVEG 88
            +TP +T         P P P         TQ P   P   + TV   P P G ++     
Sbjct: 3688 QTPTTTPITTTTTVTPTPTP-------TGTQTPTTTPITTTTTVTPTPTPTGTQT----- 3735

Query: 89   SPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVDTFQTLEPRASDAKNQEGKVNTRR 148
             P   P  + + V     P   +GT          + T  T+ P  +    Q        
Sbjct: 3736 -PTTTPITTTTTVTPTPTP---TGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3788

Query: 149  KSTDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKP 208
             +T   P    T +++           +++       + P    TG+ + ++T   T   
Sbjct: 3789 TTTTVTPTPTPTGTQT----------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3838

Query: 209  RPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLASETKTESAKTEGPSPALLEE 268
              P+      T+ PT TP    T   P      P+G    + T   +  T  P+P     
Sbjct: 3839 VTPT-PTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTP----- 3889

Query: 269  TPLEPAVGPKAACPLDSESAEGVVP-PASGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSD 327
            TP     G +        +   V P P   G +   + P+   T    T    G  TP+ 
Sbjct: 3890 TP----TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3945

Query: 328  SGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPE 387
            +     +                          P PT    + P          +  TP 
Sbjct: 3946 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 4005

Query: 388  KLDN-TPASPP-RSPAEPNDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPK-LPQQS 444
                 TP + P  +       P   GT T        P   P ++T+ +  +P     Q+
Sbjct: 4006 PTGTQTPTTTPITTTTTVTPTPTPTGTQT--------PTTTPITTTTTVTPTPTPTGTQT 4057

Query: 445  YNFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPL 504
                P T   +V P  T + T  +P+ +P +     +              P     T  
Sbjct: 4058 PTTTPITTTTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 4116

Query: 505  KTDTFRVKKSPKRSPLSDPPSQDPTPAAT----PETPPV 539
             T T    ++P  +P++   +  PTP  T    P T P+
Sbjct: 4117 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4155


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.305    0.124    0.343 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,624,949
Number of Sequences: 37866
Number of extensions: 2808179
Number of successful extensions: 35291
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 485
Number of HSP's successfully gapped in prelim test: 1833
Number of HSP's that attempted gapping in prelim test: 16880
Number of HSP's gapped (non-prelim): 12891
length of query: 1026
length of database: 18,247,518
effective HSP length: 112
effective length of query: 914
effective length of database: 14,006,526
effective search space: 12801964764
effective search space used: 12801964764
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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