Guide to the Human Genome
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Search of human proteins with 169167670

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169167670 PREDICTED: similar to hCG1646049 [Homo sapiens]
         (346 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239754042 PREDICTED: similar to hCG1646049 [Homo sapiens]          712   0.0  
gi|239748572 PREDICTED: similar to hCG1646049 [Homo sapiens]          712   0.0  
gi|169167670 PREDICTED: similar to hCG1646049 [Homo sapiens]          712   0.0  
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    63   4e-10
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo...    58   1e-08
gi|169160903 PREDICTED: hypothetical protein [Homo sapiens]            55   9e-08
gi|224465238 hypothetical protein LOC283999 [Homo sapiens]             53   5e-07
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        53   5e-07
gi|239748752 PREDICTED: hypothetical protein XP_002346787 [Homo ...    52   6e-07
gi|239757987 PREDICTED: hypothetical protein [Homo sapiens]            52   1e-06
gi|40789265 beta 1,4-N-acetylgalactosaminyltransferase-transfera...    52   1e-06
gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens]                52   1e-06
gi|23510413 sorting nexin 26 [Homo sapiens]                            50   3e-06
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...    50   4e-06
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...    50   4e-06
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     50   4e-06
gi|239740948 PREDICTED: hypothetical protein LOC644246 [Homo sap...    49   5e-06
gi|182507165 thymus expressed gene 3-like [Homo sapiens]               49   9e-06
gi|239754657 PREDICTED: hypothetical protein XP_002346062 [Homo ...    48   1e-05
gi|239743279 PREDICTED: hypothetical protein XP_002342816 [Homo ...    48   1e-05
gi|239508962 PREDICTED: hypothetical protein [Homo sapiens]            48   1e-05
gi|188536004 zinc finger protein 469 [Homo sapiens]                    48   1e-05
gi|148229134 ring finger and KH domain containing 2 [Homo sapiens]     48   1e-05
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         48   1e-05
gi|239749199 PREDICTED: hypothetical protein XP_002346952 [Homo ...    47   2e-05
gi|239756550 PREDICTED: hypothetical protein XP_002344932 [Homo ...    47   3e-05
gi|239749077 PREDICTED: hypothetical protein XP_002346898 [Homo ...    47   3e-05
gi|239746104 PREDICTED: hypothetical protein XP_002344198 [Homo ...    47   3e-05
gi|239745514 PREDICTED: hypothetical protein XP_002343509 [Homo ...    47   3e-05
gi|239743103 PREDICTED: hypothetical protein XP_002342755 [Homo ...    47   3e-05

>gi|239754042 PREDICTED: similar to hCG1646049 [Homo sapiens]
          Length = 346

 Score =  712 bits (1837), Expect = 0.0
 Identities = 346/346 (100%), Positives = 346/346 (100%)

Query: 1   MLSVSGSDPQVLEEHPSRKLGRYRSPTPLRPAKGKTICTRFGDKRSSGQAGNKSERELQA 60
           MLSVSGSDPQVLEEHPSRKLGRYRSPTPLRPAKGKTICTRFGDKRSSGQAGNKSERELQA
Sbjct: 1   MLSVSGSDPQVLEEHPSRKLGRYRSPTPLRPAKGKTICTRFGDKRSSGQAGNKSERELQA 60

Query: 61  RTPAPPRERGESSSPRGPTLRGRAKTTRGRSQGAGATETSAGNSAATAAPHPTPASYPQG 120
           RTPAPPRERGESSSPRGPTLRGRAKTTRGRSQGAGATETSAGNSAATAAPHPTPASYPQG
Sbjct: 61  RTPAPPRERGESSSPRGPTLRGRAKTTRGRSQGAGATETSAGNSAATAAPHPTPASYPQG 120

Query: 121 TISPPQLPAPRPKRFGGKQRPLWRIRGWETTVARLPEPRVGKLGKGPPPRPAPPGTRCCP 180
           TISPPQLPAPRPKRFGGKQRPLWRIRGWETTVARLPEPRVGKLGKGPPPRPAPPGTRCCP
Sbjct: 121 TISPPQLPAPRPKRFGGKQRPLWRIRGWETTVARLPEPRVGKLGKGPPPRPAPPGTRCCP 180

Query: 181 GARAAQLLREAAAAAQGLRAPAARLPEPTRRAPGRPGCLPTAAAAAADALWRSRRAPLPP 240
           GARAAQLLREAAAAAQGLRAPAARLPEPTRRAPGRPGCLPTAAAAAADALWRSRRAPLPP
Sbjct: 181 GARAAQLLREAAAAAQGLRAPAARLPEPTRRAPGRPGCLPTAAAAAADALWRSRRAPLPP 240

Query: 241 TEFLSPRRTRPRKHPERTRRPAQRLESGCRGHCSRGAPALAPPKLSPPFPCLAQSASRAA 300
           TEFLSPRRTRPRKHPERTRRPAQRLESGCRGHCSRGAPALAPPKLSPPFPCLAQSASRAA
Sbjct: 241 TEFLSPRRTRPRKHPERTRRPAQRLESGCRGHCSRGAPALAPPKLSPPFPCLAQSASRAA 300

Query: 301 GARRALSASRGRRGLLGSGSLALPLPGCREPRQRLHGSDGAAGARC 346
           GARRALSASRGRRGLLGSGSLALPLPGCREPRQRLHGSDGAAGARC
Sbjct: 301 GARRALSASRGRRGLLGSGSLALPLPGCREPRQRLHGSDGAAGARC 346


>gi|239748572 PREDICTED: similar to hCG1646049 [Homo sapiens]
          Length = 346

 Score =  712 bits (1837), Expect = 0.0
 Identities = 346/346 (100%), Positives = 346/346 (100%)

Query: 1   MLSVSGSDPQVLEEHPSRKLGRYRSPTPLRPAKGKTICTRFGDKRSSGQAGNKSERELQA 60
           MLSVSGSDPQVLEEHPSRKLGRYRSPTPLRPAKGKTICTRFGDKRSSGQAGNKSERELQA
Sbjct: 1   MLSVSGSDPQVLEEHPSRKLGRYRSPTPLRPAKGKTICTRFGDKRSSGQAGNKSERELQA 60

Query: 61  RTPAPPRERGESSSPRGPTLRGRAKTTRGRSQGAGATETSAGNSAATAAPHPTPASYPQG 120
           RTPAPPRERGESSSPRGPTLRGRAKTTRGRSQGAGATETSAGNSAATAAPHPTPASYPQG
Sbjct: 61  RTPAPPRERGESSSPRGPTLRGRAKTTRGRSQGAGATETSAGNSAATAAPHPTPASYPQG 120

Query: 121 TISPPQLPAPRPKRFGGKQRPLWRIRGWETTVARLPEPRVGKLGKGPPPRPAPPGTRCCP 180
           TISPPQLPAPRPKRFGGKQRPLWRIRGWETTVARLPEPRVGKLGKGPPPRPAPPGTRCCP
Sbjct: 121 TISPPQLPAPRPKRFGGKQRPLWRIRGWETTVARLPEPRVGKLGKGPPPRPAPPGTRCCP 180

Query: 181 GARAAQLLREAAAAAQGLRAPAARLPEPTRRAPGRPGCLPTAAAAAADALWRSRRAPLPP 240
           GARAAQLLREAAAAAQGLRAPAARLPEPTRRAPGRPGCLPTAAAAAADALWRSRRAPLPP
Sbjct: 181 GARAAQLLREAAAAAQGLRAPAARLPEPTRRAPGRPGCLPTAAAAAADALWRSRRAPLPP 240

Query: 241 TEFLSPRRTRPRKHPERTRRPAQRLESGCRGHCSRGAPALAPPKLSPPFPCLAQSASRAA 300
           TEFLSPRRTRPRKHPERTRRPAQRLESGCRGHCSRGAPALAPPKLSPPFPCLAQSASRAA
Sbjct: 241 TEFLSPRRTRPRKHPERTRRPAQRLESGCRGHCSRGAPALAPPKLSPPFPCLAQSASRAA 300

Query: 301 GARRALSASRGRRGLLGSGSLALPLPGCREPRQRLHGSDGAAGARC 346
           GARRALSASRGRRGLLGSGSLALPLPGCREPRQRLHGSDGAAGARC
Sbjct: 301 GARRALSASRGRRGLLGSGSLALPLPGCREPRQRLHGSDGAAGARC 346


>gi|169167670 PREDICTED: similar to hCG1646049 [Homo sapiens]
          Length = 346

 Score =  712 bits (1837), Expect = 0.0
 Identities = 346/346 (100%), Positives = 346/346 (100%)

Query: 1   MLSVSGSDPQVLEEHPSRKLGRYRSPTPLRPAKGKTICTRFGDKRSSGQAGNKSERELQA 60
           MLSVSGSDPQVLEEHPSRKLGRYRSPTPLRPAKGKTICTRFGDKRSSGQAGNKSERELQA
Sbjct: 1   MLSVSGSDPQVLEEHPSRKLGRYRSPTPLRPAKGKTICTRFGDKRSSGQAGNKSERELQA 60

Query: 61  RTPAPPRERGESSSPRGPTLRGRAKTTRGRSQGAGATETSAGNSAATAAPHPTPASYPQG 120
           RTPAPPRERGESSSPRGPTLRGRAKTTRGRSQGAGATETSAGNSAATAAPHPTPASYPQG
Sbjct: 61  RTPAPPRERGESSSPRGPTLRGRAKTTRGRSQGAGATETSAGNSAATAAPHPTPASYPQG 120

Query: 121 TISPPQLPAPRPKRFGGKQRPLWRIRGWETTVARLPEPRVGKLGKGPPPRPAPPGTRCCP 180
           TISPPQLPAPRPKRFGGKQRPLWRIRGWETTVARLPEPRVGKLGKGPPPRPAPPGTRCCP
Sbjct: 121 TISPPQLPAPRPKRFGGKQRPLWRIRGWETTVARLPEPRVGKLGKGPPPRPAPPGTRCCP 180

Query: 181 GARAAQLLREAAAAAQGLRAPAARLPEPTRRAPGRPGCLPTAAAAAADALWRSRRAPLPP 240
           GARAAQLLREAAAAAQGLRAPAARLPEPTRRAPGRPGCLPTAAAAAADALWRSRRAPLPP
Sbjct: 181 GARAAQLLREAAAAAQGLRAPAARLPEPTRRAPGRPGCLPTAAAAAADALWRSRRAPLPP 240

Query: 241 TEFLSPRRTRPRKHPERTRRPAQRLESGCRGHCSRGAPALAPPKLSPPFPCLAQSASRAA 300
           TEFLSPRRTRPRKHPERTRRPAQRLESGCRGHCSRGAPALAPPKLSPPFPCLAQSASRAA
Sbjct: 241 TEFLSPRRTRPRKHPERTRRPAQRLESGCRGHCSRGAPALAPPKLSPPFPCLAQSASRAA 300

Query: 301 GARRALSASRGRRGLLGSGSLALPLPGCREPRQRLHGSDGAAGARC 346
           GARRALSASRGRRGLLGSGSLALPLPGCREPRQRLHGSDGAAGARC
Sbjct: 301 GARRALSASRGRRGLLGSGSLALPLPGCREPRQRLHGSDGAAGARC 346


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 62.8 bits (151), Expect = 4e-10
 Identities = 91/326 (27%), Positives = 114/326 (34%), Gaps = 68/326 (20%)

Query: 74  SPRGPTLRGRAKTTRGR-------SQGAGATETSAGNSAATAAPHPTPASYPQGTISPPQ 126
           +PR P +R  A    G        +  AGA   +    A  AAP P PA   +     PQ
Sbjct: 44  APRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQ 103

Query: 127 LPAP----RPKRFGGKQRPLWRIR-------------GWETTVARLPEPR---------- 159
            P P    RP    G   P  ++R                  VA  PEP           
Sbjct: 104 RPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGP 163

Query: 160 ---VGKLGKGPPPRPAP-----PGTRCCPGAR-----AAQLLREAAAAAQGL----RAPA 202
                + G GP P P P     PG    PGA      +A LL    AAA  +      PA
Sbjct: 164 AALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPA 223

Query: 203 ARLPEPTRRAPGRPGCLPTAAAAAADALWRSRRAPLPPTEFLSPRRTRPRKHPERTRRPA 262
           A LP P   APG     P    AAA        AP  P+   +P    P   P     PA
Sbjct: 224 ALLPLPKPAAPGTVIQTPPFVGAAAPP------APAAPSPPAAPAPAAPAAAPP-PPPPA 276

Query: 263 QRLESGCRGHCSRGAPALAPPKLSPPFPCLAQSASRAAGARRALSASRGRRGLLG----S 318
               +   GH   G P  AP   + P P  AQ+   A  A     A+ G  G+ G     
Sbjct: 277 PATLARPPGH-PAGPPTAAP---AVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPG 332

Query: 319 GSLALPLPGCR--EPRQRLHGSDGAA 342
            + A P PG +   P++ +  +  AA
Sbjct: 333 AAAAAPAPGVKAESPKRVVQAAPPAA 358



 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 57/192 (29%), Positives = 69/192 (35%), Gaps = 31/192 (16%)

Query: 94  AGATETSAGNSAATAAPHPTPASYPQGTISPPQLPAPRPKRFGGKQRPLWRIRGWETTVA 153
           A  +  +A   AA AA  P P   P     PP  PA  P        P     G     A
Sbjct: 253 AAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAA 312

Query: 154 RLPEPRVG-KLGKGPPPRPAPPGTRCCPGARA---AQLLREAAAAAQGLRA--PAA---- 203
             P P  G   G    P P        PG +A    ++++ A  AAQ L A  PA+    
Sbjct: 313 PAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAAS 372

Query: 204 ---------RLPEPTR---RAPGRPGCLPTAAAAAA--------DALWRSRRAPLPPTEF 243
                     LP P      APG P  LP  AA A          A     RA L PT  
Sbjct: 373 MVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPT-V 431

Query: 244 LSPRRTRPRKHP 255
           L+PR  +P ++P
Sbjct: 432 LAPRLPQPPQNP 443


>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
           sapiens]
          Length = 483

 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 94/330 (28%), Positives = 111/330 (33%), Gaps = 44/330 (13%)

Query: 31  PAKGKTICTRFGDKRSSGQ---AGNKSERELQARTPAPPRERGESSSPRGPTLRGRAKTT 87
           P  G      F   R +GQ   AG K+ +   +R P+P       S P  P    R   T
Sbjct: 96  PTLGDLFAGGFPVLRPAGQRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNT 155

Query: 88  RGRSQGAGATETSAGNSAATAAPHPTPASYPQGTISPPQLPAPRPKRFGGK-QRPLWRIR 146
                      + A  +A TA P P   + P  T  PP  P P P       + PL    
Sbjct: 156 -----------SEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPP 204

Query: 147 GWETTVARLPEPRVGKLGKGPPPRPAPPGTRCCPGARAAQLLREAAAAAQ--GLRAPAAR 204
           G   T   LP          PPP P PP T   P    A +L + A   Q   L  P   
Sbjct: 205 G-PLTKGNLPVVAPPVPCAPPPPPPPPPPTP--PPLPPASVLSDKAVKPQLAPLHLPPIP 261

Query: 205 LPEPTRRAPGRPGCLPTAAAAAADALW-RSRRAPLPPTEFLSPRRTRPRKHPERTRRPAQ 263
            P P     G PG     A+ A DA    +   PLPP    SPR + P         P  
Sbjct: 262 PPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAP-------PLP 314

Query: 264 RLESGCRGHCSRGAPALAPPKLSPPFPCLAQSASRAA--------GARRALSASRGRRGL 315
            + S      S   P   PPK SP F    Q A   A        G++  L   R  R  
Sbjct: 315 GVNS------SSETPPPLPPK-SPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPG 367

Query: 316 LGSGSL-ALPLPGCREPRQRLHGSDGAAGA 344
            G G L   P P  R P   L      A A
Sbjct: 368 AGGGKLNPPPAPPARSPTTELSSKSQQATA 397


>gi|169160903 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 426

 Score = 55.1 bits (131), Expect = 9e-08
 Identities = 80/273 (29%), Positives = 96/273 (35%), Gaps = 68/273 (24%)

Query: 81  RGRAKTTRGRSQGAGATETSAGNSAATAAPHPTPASYPQGTISPPQLPAPRPKRFGGKQR 140
           RG+  T   R+   G  E  A     T AP P   S P     PP LPAP        QR
Sbjct: 3   RGQRFTPHPRTPAPGCPEV-APQPEGTDAPGPAVCS-PTARAPPPILPAP--------QR 52

Query: 141 PLWRIRGWETTV----------ARLPEPRVGKLGK--------GPPPRPAPPGTRCCPGA 182
           P  R R WE             A L  P   +LG+         P P P  P  R   G 
Sbjct: 53  PPTRAREWEGAAWAAGATGVGAALLALPGSRRLGRVPLTFREASPGPAPGAPRARGSCGR 112

Query: 183 RAAQLLREAAAAAQGLRAPAARLPEPTRRAPGRPGCLPTAAAAAADALWRSRRAPLPPTE 242
                 R A ++A    A AAR   P +R+  R  CLP +  +                 
Sbjct: 113 EPGPRRRRAPSSAGKRPAAAARAAPPRQRSLAR--CLPRSVGSC---------------- 154

Query: 243 FLSPRRTRPRKHPERTRRPAQRLESGCRGHCSRGAPALAPPKLSPPFPCLA--QSASRAA 300
                  RP   P   RR  +R    CR HC R  P   PP L P     +  + A+  A
Sbjct: 155 ------VRPSVGPSLPRRHCRR---HCRCHCRR-RPLPKPPPLQPRLGSASPPRLAAPLA 204

Query: 301 GARR-ALS------ASRGRRGLLGSGSLALPLP 326
           G+R  +LS        R  R   G G   LPLP
Sbjct: 205 GSRAPSLSPFPRRCRRRAERSPAGHG---LPLP 234



 Score = 35.0 bits (79), Expect = 0.099
 Identities = 53/198 (26%), Positives = 70/198 (35%), Gaps = 36/198 (18%)

Query: 63  PAPPRERGESSSPRGPTLRGRAKTTRGRSQGAGATETSAGNSAATAAPHPTPASYPQGTI 122
           P  PR RG      GP  R RA ++ G+   A A        +       +  S  + ++
Sbjct: 101 PGAPRARGSCGREPGPR-RRRAPSSAGKRPAAAARAAPPRQRSLARCLPRSVGSCVRPSV 159

Query: 123 SP--PQLPAPRPKRFGGKQRPLWRIRGWETTVARLPEPRVGKLGKGPPPRPAPP--GTRC 178
            P  P+    R  R   ++RPL +           P P   +LG   PPR A P  G+R 
Sbjct: 160 GPSLPRRHCRRHCRCHCRRRPLPK-----------PPPLQPRLGSASPPRLAAPLAGSRA 208

Query: 179 ---CPGARAAQLLREAAAAAQGLRAPAA------------RLPEPTRRAPG-RPGCL--- 219
               P  R  +   E + A  GL  P +            R     RR  G R GC    
Sbjct: 209 PSLSPFPRRCRRRAERSPAGHGLPLPRSLSRGGEVVGARRRRGGEERRVRGRRQGCALGS 268

Query: 220 -PTAAAAAADALWRSRRA 236
            P  A  AA      RRA
Sbjct: 269 PPIPAGPAAPGRAGERRA 286


>gi|224465238 hypothetical protein LOC283999 [Homo sapiens]
          Length = 394

 Score = 52.8 bits (125), Expect = 5e-07
 Identities = 87/278 (31%), Positives = 101/278 (36%), Gaps = 47/278 (16%)

Query: 80  LRGRA-KTTRGRSQGAGATETSAGN---SAATAAPHPTPASYPQGTISPPQ-----LPA- 129
           LR R  +  + R+QG GA+     +   S   AA   T + +PQG    PQ     LPA 
Sbjct: 68  LRSRGFREIKERAQGPGASPWGRWDWSPSPRFAARLSTSSPFPQGRAQRPQRGGVDLPAT 127

Query: 130 ---PRPK---RFGGKQRPLWRIRGWETTVARLPEPRVGKLGKGPP-PRPAPPGTRCC-PG 181
              PR +   R G   R   R R     V RLP PR  +  +GP  P P+PP  R   P 
Sbjct: 128 PGGPRGQCAGRSGDVLRRAGRRRARPPPVPRLPAPRAPRRPRGPATPDPSPPAGRPHGPA 187

Query: 182 ARAAQLLREAAAAAQGLRAPAARLPEPTRRAPGRPGCLP--------TAAAAAADALWRS 233
            RAA   R    A   LRAP  R  +     PG  G            AA  A  AL   
Sbjct: 188 GRAAPGRRPGCTAQ--LRAPGRRGRQRLLVHPGGGGRRQWQRLARARRAALLALGALAHL 245

Query: 234 RRAP-----------LPPTEFLSPRRTRPRKHPERTRRPAQRLESG------CRGHCSRG 276
           RR P           L P          P  H  R R+   RL  G      C G   R 
Sbjct: 246 RRCPDTGGGQHLHQLLAPGLCGDGAAVWPAAHAGRPRQ--LRLVHGPGLGLLCLGGIQRN 303

Query: 277 APALAPPKLSPPFPCLAQSASRAAGARRALSASRGRRG 314
            PAL+     P  P L  S S A G  R     R   G
Sbjct: 304 PPALSCLDPQPEPPNLWSSESPAGGRERGRLRPRAAEG 341


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 52.8 bits (125), Expect = 5e-07
 Identities = 89/348 (25%), Positives = 130/348 (37%), Gaps = 40/348 (11%)

Query: 22   RYRSPTPL---------RPAKGKTICTRFGDKRSSGQAGNKSERELQARTPAPPRERGES 72
            R RSP+P          R  + KT  TR  D+  S Q+ ++  +  ++R+    R RG S
Sbjct: 1759 RGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGS 1818

Query: 73   S-SPRGPTLRGRAKTTRGRSQGAGATE-TSAGNSAATAAPHP--------TPASYPQGTI 122
                R P  +  ++T+  R +G   T  TS   S +  +P P        +PA++ +   
Sbjct: 1819 GYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRS 1878

Query: 123  SPPQLPAPRPKRFGGKQRPLWRIRGWETT--VARLPEPRVGKLGKGPPPRPAPPGTRCCP 180
              P +   R +    +  P+ R R    T    R    R   + +       PP TR   
Sbjct: 1879 RTPLISRRRSR---SRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRS 1935

Query: 181  GARAAQLLREAAAAAQGL--RAPAARLPEPTRRAPGRPGCLPTAAAAAADALWRSRRAPL 238
             +R     R + +    +  R   +R P  TRR   R    P     +     RSR +P+
Sbjct: 1936 RSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRR-SRSRTSPITRRRS-----RSRTSPV 1989

Query: 239  PPTEFLSPRRTRPRKHPERTRRPAQRLESGCRGHC-SRGAPALAPPKLS-PPFPCLAQSA 296
                  + RR+R R  P   RR   R     R    SR  PA+     S  P     +S 
Sbjct: 1990 ------TRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSR 2043

Query: 297  SRAAGARRALSASRGRRGLLGSGSLALPLPGCREPRQRLHGSDGAAGA 344
            SR+  A R  S SR  R   G  SL    P  R        SD +  A
Sbjct: 2044 SRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSA 2091



 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 88/340 (25%), Positives = 126/340 (37%), Gaps = 32/340 (9%)

Query: 16  PSRKLGRYRSPTPLRPAKGKT-ICTRFGDKRSSGQAGNKSERELQARTPAPPRERGESSS 74
           PSR++GR RSP   +  + ++   T+ G  RS      +S    +      P+ RG S S
Sbjct: 477 PSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRS 536

Query: 75  PRGP-TLRGRAKTTRGRSQGAGATETSAGNSAATAAPHP-TPASYPQGTISPPQLPAPRP 132
           P+ P   R R    RGRS+ A    + + + A        TPA   +   S  + PA R 
Sbjct: 537 PQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGR---SRSRTPARRR 593

Query: 133 KRFGGKQRPLWRIRGWETTVARLPEPRVGKLGKGPPPRPAPPGTRC-CPGARAAQLLREA 191
            R     R   R R    T AR         G+     PA   +R   P  R ++    A
Sbjct: 594 SR----SRTPTRRRSRSRTPAR--------RGRSRSRTPARRRSRTRSPVRRRSRSRSPA 641

Query: 192 AAAAQGLRAPAARLPEPTRRAPGRPGCLPTAAAAAADALWRSRR-APLPPTEFLSPRRTR 250
             + +      AR      R P R G   +   A      RSR  A    +   +PRR R
Sbjct: 642 RRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGR 701

Query: 251 PRKHP------ERTRRPAQRLESGC---RGHCSRGAPALAPPKLSPPFPCLAQSASRAAG 301
            R           +R P +R  SG    R + SR +   +    SP       S+ R+  
Sbjct: 702 SRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRS 761

Query: 302 ARRALSASRGRRGLLGSGSLALPLPGCRE---PRQRLHGS 338
                S ++ R  L  S S + P P  +    PR+   GS
Sbjct: 762 LSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGS 801



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 72/318 (22%), Positives = 113/318 (35%), Gaps = 50/318 (15%)

Query: 16  PSRKLGRYRSPTPLRPAKGKTICTRFGDKRSS----------------GQAGNKSERELQ 59
           P+R+ GR RS TP R  + ++   R G  RS                 G++G+ SER+ +
Sbjct: 674 PARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNK 733

Query: 60  ARTPAPPRERGESSSPRGPTLRGRAKTTRGRS--QGAGATETSAGNSAATAAPHP----- 112
           +RT    R    +SSP     R  ++ +R  S  +    +  S   S + ++P P     
Sbjct: 734 SRTSQ--RRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQ 791

Query: 113 TPASYPQGTISPPQLPA---PRPKRFGGKQRPLWRIR--GWETTVARLPEPRVGKLGKGP 167
           TP    +   S P+  +   PR  R      P  + +    ++  +  P P+V     G 
Sbjct: 792 TPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKS---GT 848

Query: 168 PPRPAP------------PGTRCCPGARAAQLLREAAAA---AQGLRAPAARLPEPTRRA 212
           PPR               P  R C  +     L+    +     G   P  +   P R++
Sbjct: 849 PPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQS 908

Query: 213 PGRPGCLPTAAAAAADALWRSRRAPLPPTEFLSPRRTRPRKHPERTRRPAQRLESGCRGH 272
           P R         A      RS      P+      RT PR+   R+  P   +ES     
Sbjct: 909 PSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRR--SRSVSPCSNVESRLLPR 966

Query: 273 CSRGAPALAPPKLSPPFP 290
            S    +    K+ P  P
Sbjct: 967 YSHSGSSSPDTKVKPETP 984



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 85/365 (23%), Positives = 130/365 (35%), Gaps = 68/365 (18%)

Query: 3    SVSGSDPQVLEEH---PSRKLGRYRSPTPLRPA--------------KGK---------- 35
            S SGS P+V ++    P  + G   SP P  PA              KG+          
Sbjct: 1596 SRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSST 1655

Query: 36   TICTRFGDKRSSGQAGNKSERELQARTPAPPRERGESSSP---RGPTLRGRAKTTRGRSQ 92
                    K  + + G++S  E + ++  PPR R   SSP   R   L  R+++     +
Sbjct: 1656 ESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPE 1715

Query: 93   GAGATETSAGNSAATAAPHP---TPASYPQGTISPPQL---------PAPRPKRFGGKQR 140
                T      S + ++P P   + +S  + + S P+          P+P+P+   G QR
Sbjct: 1716 TRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPR---GLQR 1772

Query: 141  PLWRIRGWETTVARLPEPRVGKLGKGPPPRPAPPGTRCCPGARAAQLLREAAAAAQGLRA 200
               R R  +T   R    R  + G           +R    +R+    R    +    R+
Sbjct: 1773 SRSRSRREKTRTTR----RRDRSGSSQSTSRRRQRSR----SRSRVTRRRRGGSGYHSRS 1824

Query: 201  PAARLPEPT--RRAPGRPGCLPT----AAAAAADALWRSRRAPLPP---------TEFLS 245
            PA +    T  RR  GR    PT    + +  + A W+  R+   P         T  +S
Sbjct: 1825 PARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLIS 1884

Query: 246  PRRTRPRKHPERTRRPAQRLESGCRGHCSRGAPALAPPKLSPPFPCLAQSASRAAGARRA 305
             RR+R R  P   RR   R     R   SR +P       S   P   + +       R 
Sbjct: 1885 RRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRR 1944

Query: 306  LSASR 310
             S SR
Sbjct: 1945 RSRSR 1949



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 74/331 (22%), Positives = 120/331 (36%), Gaps = 73/331 (22%)

Query: 5    SGSDPQVLEEHPSRKLGRYRSP-------TPLRPAKG-------KTIC-TRFGDKRSSG- 48
            S  +P+ L + P  +     SP       TP R   G       KT+  T  G +  SG 
Sbjct: 1482 SSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGS 1541

Query: 49   --------------QAGNKSERELQARTPAPPRERGESSSPRGPTLRGRAKTTRGRSQGA 94
                          ++ + S  + +A+T  P R+R  S S   P +  +++ +  RS+  
Sbjct: 1542 SQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGS--SPEVDSKSRLSPRRSRSG 1599

Query: 95   GATETSAGNSAATAAPHPTPASYPQGTISPPQLPAPRPKRFGGKQRPLWRIRG------- 147
             + E      AA  A          G+ S P+  AP P+    + R     +G       
Sbjct: 1600 SSPEVKDKPRAAPRA--------QSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEG 1651

Query: 148  ---WETTVARLPEPRVGKLGKGPPPRP-----APPGTRCCPGA----RAAQLLREAAAAA 195
                E++    P+ R  + G    P P      PP  R    +    R A+L R + +A+
Sbjct: 1652 SSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSAS 1711

Query: 196  QG-----------LRAPAARLPEPTRRAPGRPGCLPTAAAAAADALWRSRRAPLPPTEFL 244
                          R+P+   PEP  ++          +A++      SRR   P  +  
Sbjct: 1712 SSPETRSRTPPRHRRSPSVSSPEPAEKS---RSSRRRRSASSPRTKTTSRRGRSPSPKPR 1768

Query: 245  SPRRTRPRKHPERTRRPAQRLESGCRGHCSR 275
              +R+R R   E+TR   +R  SG     SR
Sbjct: 1769 GLQRSRSRSRREKTRTTRRRDRSGSSQSTSR 1799



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 89/346 (25%), Positives = 127/346 (36%), Gaps = 61/346 (17%)

Query: 17   SRKLGRYR-SPTPLRPAKGKTI-CTRFGDKRSSGQAGNKSERELQARTPAPPRERGESSS 74
            +R+  R R SP   R ++ +T   TR   +RS  +      R  ++RTP  PR+R  S S
Sbjct: 1990 TRRRSRSRTSPVTRRRSRSRTSPVTR---RRSRSRTPPAIRRRSRSRTPLLPRKRSRSRS 2046

Query: 75   PRGPTLRGRAKTTR--------GRSQGAGATETSAGNSA--ATAAPHPTPASYPQGTISP 124
            P     R R++T R         RS  A    +++G+S+  + +A  P   ++      P
Sbjct: 2047 PLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPP 2106

Query: 125  PQLPAPRPKRFGG---KQRPLWRIR--------GWETTVARLPEPRVGKLGKGPPPRPAP 173
              L + R   F        PL R R        G   T   + +   G +  GP PR   
Sbjct: 2107 VALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPD 2166

Query: 174  PGTRCCPGARAAQLLREAAAA-------------AQGLRAPAARLPEPT-----RRAPGR 215
                  P   A   +  A  A             A GL A  +++P P      R AP  
Sbjct: 2167 HQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAA 2226

Query: 216  PGCLPTAAAAAADALWRSRRAPLPPTEF-LSPRRTRPRKHPERTRRPAQRLESGCRGHCS 274
                   AA+AA     S R P  PT   L+  RT           P        R   +
Sbjct: 2227 NLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASP--------RTAVA 2278

Query: 275  RGAPALAPPKLSPPFPCLAQSASRAAGARRALSASRGRRGLLGSGS 320
              A  LA P+ +P  P +  + +R   A  ALS       L GSG+
Sbjct: 2279 PSAVNLADPR-TPTAPAVNLAGARTPAALAALS-------LTGSGT 2316



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 66/278 (23%), Positives = 97/278 (34%), Gaps = 27/278 (9%)

Query: 57  ELQARTPAPPRERGESSSPRGPTLRGRAKTTRGRSQGAGATETSAGNSAATAAPHPTPAS 116
           E    +P P      S  P  P     A  TR RS      +    +S+ ++ P P P  
Sbjct: 372 ERHGGSPQPLATTPLSQEPVNPP--SEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTK 429

Query: 117 YPQGTISPPQLPAPRP----------------KRFGGKQRPLWRIRGWETTVARLPEPRV 160
             +   S P+ P P P                +  G  +R           + R   P  
Sbjct: 430 VSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPAT 489

Query: 161 GKLGKGPPPRPAPPGTRCCPGARAAQLLREAAAAAQG-LRAPAARLPEPTRRAPGRPGCL 219
            K G+    R   P  R    +R+ Q  R  +A   G  R+P  R    + + PG     
Sbjct: 490 AKRGRS---RSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSR 546

Query: 220 PTAAAAAADALWRSR-RAPLPPTEFLSPRRTRPRKHPERTRRPAQRLESGCRGHCSRGAP 278
            T     + +  R R  +  P T   S  RT  R+   R+R PA+R  S  R    R + 
Sbjct: 547 NTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARR-RSRSRTPTRRRSR 605

Query: 279 ALAPPKLS---PPFPCLAQSASRAAGARRALSASRGRR 313
           +  P +        P   +S +R+   RR+ S S  RR
Sbjct: 606 SRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARR 643



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 41/174 (23%), Positives = 74/174 (42%), Gaps = 28/174 (16%)

Query: 3    SVSGSDPQVLEEHPSRKLGRYRSPTPLRPAKGKTICTRFGDKRSSGQAGNKSERELQART 62
            S S S+   L   P   L R  SPTP                + + + G   E      T
Sbjct: 2559 SSSDSEGSSLPVQPEVALKRVPSPTPA--------------PKEAVREGRPPEP-----T 2599

Query: 63   PAPPRERGESSSPRGPTLRGRAKTTRGRSQGAGATETSAGNSAATAAPHPTPAS-YPQGT 121
            PA  + R  SSS    +    + ++   S  + ++ +S+ +S+++++  P+PA   PQ  
Sbjct: 2600 PAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQAL 2659

Query: 122  ISP--PQLPAPRPKRFGGKQRPLWRIRGWETTVARLPEPRVGKLGKGPPPRPAP 173
              P  P+ P P  +R    ++P+  +R    +++  P  R     + P P+P+P
Sbjct: 2660 PKPASPKKPPPGERRSRSPRKPIDSLRD-SRSLSYSPVER-----RRPSPQPSP 2707



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 64/284 (22%), Positives = 118/284 (41%), Gaps = 22/284 (7%)

Query: 16  PSRKLGRYRSPTPLRP-AKGKTICTRFGDKRSSGQAGNKSER---ELQARTPAPPRERGE 71
           P+R+ GR RS TP R  ++ +T   R    R+  + G    R     ++RT +P R R  
Sbjct: 578 PARR-GRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSR 636

Query: 72  SSSPRGPTLRGRAKT--TRGRSQGAGATETSAGNSAATAAPHPTPASYPQGTISPPQLPA 129
           S SP   + R R++T   RGRS+    T    G S +      +  S  +      +  +
Sbjct: 637 SRSPARRSGRSRSRTPARRGRSR--SRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRS 694

Query: 130 PRPKRFGGKQRPLWRIRGWETTVARLPEPRVGKLGKGPPPRPAPPGTRCCPGARAAQLLR 189
             P+R   + R L R RG   + +R P+ R G+ G     +     ++    + ++  ++
Sbjct: 695 RTPRRGRSRSRSLVR-RG--RSHSRTPQRR-GRSGSSSERKNKSRTSQRRSRSNSSPEMK 750

Query: 190 EAAAAAQGLRAPAARLPEPTRRAPGRPGCLPTAAAAAADALWRSRRAPLPPTEFLSPRRT 249
           ++  +++  R+    L  P  +A  R     + + ++     +S+  P       S  + 
Sbjct: 751 KSRISSRRSRS----LSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKA 806

Query: 250 RPRKHPERTRR-----PAQRLESGCRGHCSRGAPALAPPKLSPP 288
           + R  P R+R      P Q+ ++  R   S  +P       +PP
Sbjct: 807 KSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPP 850



 Score = 37.7 bits (86), Expect = 0.015
 Identities = 87/392 (22%), Positives = 133/392 (33%), Gaps = 100/392 (25%)

Query: 18  RKLGRYRSPTPLRPAKGK---------TICTRFGDKRSSGQAGNKSERELQA---RTPAP 65
           R+    RSPTP +  K K         +   R   K+SS +  ++SE E +    R+P P
Sbjct: 175 RESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTP 234

Query: 66  ---------PRERGESSSPRGPTLRGR----------AKTTRGRSQGA------------ 94
                     R+R  S++P   + R            + T+R RS+ A            
Sbjct: 235 KSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGR 294

Query: 95  -------------------GATETSAGNSAATAAPHPT-----------------PASYP 118
                              G T T   +S  TA   P+                 P+  P
Sbjct: 295 SPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSP 354

Query: 119 QGTISPPQLPAPRP---KRFGGKQRPLWRI----------RGWETTVARLPEPRVGKLGK 165
           + + + P+ PAP P   +R GG  +PL                  T  R P     KL +
Sbjct: 355 ERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQ 414

Query: 166 GPPPRPAPPGTRCCPGARAAQLLREA--AAAAQGLRAPAARLPEPTRRAPGRPGCLPTAA 223
                 +PP  +    +R A    E+   A A G     +  P    R+ GR     + +
Sbjct: 415 SSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHS 474

Query: 224 AAAADALWRSRRAPLPPTEFLSPRRTRPRKHPERTRRPAQRLESGCRGHCSRGAPALAPP 283
              +  + RS R+P       S  RT  ++   R+R P  R     +      +P     
Sbjct: 475 HTPSRRMGRS-RSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGR 533

Query: 284 KLSPPFPCLAQSAS-----RAAGARRALSASR 310
             SP  P  ++S +     R+  ARR  S SR
Sbjct: 534 SRSPQRPGWSRSRNTQRRGRSRSARRGRSHSR 565



 Score = 31.2 bits (69), Expect = 1.4
 Identities = 65/315 (20%), Positives = 110/315 (34%), Gaps = 27/315 (8%)

Query: 17   SRKLGRYRSPTPLRPAKGKTICTRFGDKRSSGQAGNKSERELQARTPAPPRERGESSSPR 76
            +R+  R R+ +P+   + ++  +    +RS  +    + R  ++RT    R R  S +P 
Sbjct: 1966 TRRRSRSRT-SPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPP 2024

Query: 77   GPTLRGRAKT-----TRGRSQG---------AGATETSAGNSAATAAPHPTPASYPQGTI 122
                R R++T      R RS+          +    T+ G  + T +P         G+ 
Sbjct: 2025 AIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSS 2084

Query: 123  SPPQLPA--PRPKRFGGKQRPLWRIRGWETTVARLPEPRVGKLGKGPPPRPAPPGTRCCP 180
            S     A  P  +   G + P   +     +    P      +   P  R   PG     
Sbjct: 2085 SDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRP-----SMSPTPLDRCRSPGMLEPL 2139

Query: 181  GARAAQLLREAAAAAQGLRAPAARLPEPTRRA-PGRPGCLPTAAAAAADALWRSRRAPLP 239
            G+    +     A    +  P  R+P+  R + P        A A  A +L  +R  P  
Sbjct: 2140 GSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSM 2199

Query: 240  PTEFLSPRRTR-PRKHPERTRRPAQRLESGCRGHCSRGAPALAPPKLSPPFPC---LAQS 295
                L+ R ++ P   P  + R A       R   +  A        +P  P    LA S
Sbjct: 2200 SAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADS 2259

Query: 296  ASRAAGARRALSASR 310
             + AA A   L++ R
Sbjct: 2260 RTPAAAAAMNLASPR 2274



 Score = 30.8 bits (68), Expect = 1.9
 Identities = 74/311 (23%), Positives = 108/311 (34%), Gaps = 62/311 (19%)

Query: 60   ARTPAPPRERGESSSPRGPTLRGRAKTTRGRSQGAGATETSAGNSAATAAPHPTPASY-- 117
            ++ PAP       ++P    L  R       +    +  T A  +A   A   TPA+   
Sbjct: 2209 SQVPAPVPLMSLRTAPAA-NLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAA 2267

Query: 118  -----PQGTISPPQLPAPRPKRFGGKQRPLWRIRGWETTVARLPEPRVGKLGKGPPPRPA 172
                 P+  ++P  +    P+       P   + G  T  A      +   G G PP  A
Sbjct: 2268 MNLASPRTAVAPSAVNLADPRT---PTAPAVNLAGARTPAALAA---LSLTGSGTPPTAA 2321

Query: 173  --PPGTRCCPGARAAQLL--REAAAAAQ----GLRAPAARLPEPTRRAPGRPGCLPTAAA 224
              P  +R      +A L+  R A A A     G R  AA  P     A   P        
Sbjct: 2322 NYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAP-------- 2373

Query: 225  AAADALWRSRRAPLPPTEFLSPR---------RTR-PRKHPERTRRPAQRLESGCRGHCS 274
            A + A   S R PL   E +S R         R+R P   P ++R  ++R  S       
Sbjct: 2374 ALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQ 2433

Query: 275  RGAPALAPPKLSPP-----------FPCL-------AQSASRAAGARRALSASRGRRGLL 316
              + +L PP    P             CL       A S S ++GA    ++S G     
Sbjct: 2434 APSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDH--- 2490

Query: 317  GSGSLALPLPG 327
             +G L++P PG
Sbjct: 2491 -NGMLSVPAPG 2500



 Score = 30.4 bits (67), Expect = 2.4
 Identities = 23/91 (25%), Positives = 35/91 (38%), Gaps = 9/91 (9%)

Query: 51   GNKSERELQARTPAPPRERGESSSPRGPTLRGRAKTTRGRSQGAGATETSAGNS------ 104
            G +    L A  PA  R    SSS    +    + ++   S    ++  S G+S      
Sbjct: 2514 GAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPE 2573

Query: 105  -AATAAPHPTPASYPQGTISPPQLPAPRPKR 134
             A    P PTPA  P+  +   + P P P +
Sbjct: 2574 VALKRVPSPTPA--PKEAVREGRPPEPTPAK 2602


>gi|239748752 PREDICTED: hypothetical protein XP_002346787 [Homo
           sapiens]
          Length = 278

 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 54/188 (28%), Positives = 66/188 (35%), Gaps = 30/188 (15%)

Query: 63  PAPPRERGESSSPRGPTLRGRAKTTRGRSQGAGATETSAGNSAATAAPHPTPASYPQGTI 122
           P PP  R   +  RGP  +GR     GR+  A         SA TA P P     P    
Sbjct: 40  PRPPPARLPRNGRRGPLWKGRGPA--GRAPAA---------SAETALPRPREPPEPGAGP 88

Query: 123 SPPQLPAPRPKRFGGKQRPLWRIRGWETTVARLPEP-------RVGKL----GKGPP--- 168
           SP + P PR  R      P  ++  W +   R   P       R+  L      GPP   
Sbjct: 89  SPKRSPPPRAPRASSLAAPEPQVGDWTSREGRRGGPCLPGARRRLFSLSVSRSSGPPRAR 148

Query: 169 ---PRPAPPGTRCCPGARAAQLLREAAAAAQGLRAPAARLPEPTRRAPGRPGCLPTAAAA 225
              P PA  G     G  A   +    A A    AP      P R  PG P CL +    
Sbjct: 149 SCAPHPAREGMATTRGPEAGLRVSGRGARAGSSTAPTRAQASPAR--PGFPPCLRSPPCP 206

Query: 226 AADALWRS 233
           A+   +RS
Sbjct: 207 ASSRAFRS 214



 Score = 37.0 bits (84), Expect = 0.026
 Identities = 38/116 (32%), Positives = 49/116 (42%), Gaps = 10/116 (8%)

Query: 199 RAPAARLPEPTRRAP---GRPGCLPTAAAAAADALWRSRRAPLPPTEFLSPRRTRPRKHP 255
           R P ARLP   RR P   GR       AA+A  AL R R  P  P    SP+R+ P + P
Sbjct: 41  RPPPARLPRNGRRGPLWKGRGPAGRAPAASAETALPRPREPP-EPGAGPSPKRSPPPRAP 99

Query: 256 ERTRRPAQRLESG--CRGHCSRGAPALAPPKLSPPFPCLAQSASRAAGARRALSAS 309
             +   A   + G        RG P L   +        + S SR++G  RA S +
Sbjct: 100 RASSLAAPEPQVGDWTSREGRRGGPCLPGARRR----LFSLSVSRSSGPPRARSCA 151


>gi|239757987 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 445

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 83/303 (27%), Positives = 111/303 (36%), Gaps = 56/303 (18%)

Query: 29  LRPAKGKTICTRFGDKRSSGQAGNKSERELQARTPAP---PRERGESS---SPRGPTLRG 82
           LR ++ +   TR G + ++ +  N+   E  +  P     P   G+     +  G  LRG
Sbjct: 125 LRKSRARLPRTRPGREDAAVRGRNRDPAEPGSLRPTSLGFPARAGQGQVQGAAPGRRLRG 184

Query: 83  RAKTTRGRSQGAGATETSAGNSAATA------------APHPTPASYPQGTISPPQLPAP 130
             KT  GRS  +G   + AG+ AATA             P P PA  P     PP  PA 
Sbjct: 185 EPKTPPGRSGPSGGVRSGAGHRAATAEHQLGAGFSVRNGPGP-PARLPPAPPGPPLRPA- 242

Query: 131 RPKRFGGKQRPLWRIRGWETTVARLPEPRV---GKLGKGPPP--RP-----APPGTRCC- 179
           RP       R   R+   E    +LP P      +    PPP  RP      PP T  C 
Sbjct: 243 RP--HNPTSRGPGRLLTCEPPSRKLPPPLPLCRSRWVLAPPPTVRPRLRVLTPPFTLLCA 300

Query: 180 --------PGARAAQLL-REAAAAAQGLRAPAARLPEPTRRAPGRPGCLPTAAAAAADAL 230
                   P  R+A L+ R A    +    P++R    +          PT A  +AD  
Sbjct: 301 LPERGSRTPSTRSAVLVDRVAGLGTELTLTPSSRRAHGSHPLSSERQAAPTRAFCSAD-- 358

Query: 231 WRSRRAPLPPTEFLSPRRTRPRKHPERTRRPAQRLESGCRGHCSRGAPALAPPKLSP-PF 289
                 PLP      P    P+   +  R+P  RL    R   + GAP    P   P P 
Sbjct: 359 ------PLPRPPSFVPSLPSPQAQGQAVRQP--RL---LRAALALGAPRGRTPSPGPGPA 407

Query: 290 PCL 292
           P L
Sbjct: 408 PAL 410



 Score = 33.5 bits (75), Expect = 0.29
 Identities = 61/234 (26%), Positives = 73/234 (31%), Gaps = 29/234 (12%)

Query: 105 AATAAPHPTPASYPQGTISPPQLPAPRPKRFGGKQRPLWRIRGWETTVARLPEPRVGK-- 162
           A   AP P   S    T+   +      KR G KQR      G     ARL    V    
Sbjct: 18  ATCQAPFPYIVSAQLPTLDKQETLVAEEKR-GWKQRGR---NGENADTARLFGTTVYTFE 73

Query: 163 -LGKGPPPRPAPPGTRCCPGARAAQLLREAAAAAQGLRAPAARLPEPTRRAPGRPGC--- 218
            LG  PP R   P +R  PG         A       R   + +P      PG PG    
Sbjct: 74  VLGALPPDRSPTPRSRVSPGVTGL-----AVGPGNPKRCQRSGVPY---EGPGAPGGQQL 125

Query: 219 ------LPTAAAAAADALWRSRRAPLPPTEFLSPRRTRPRKHPERTRRPAQRLESGCRGH 272
                 LP       DA  R R     P E   P   RP       R    +++    G 
Sbjct: 126 RKSRARLPRTRPGREDAAVRGRNRD--PAE---PGSLRPTSLGFPARAGQGQVQGAAPGR 180

Query: 273 CSRGAPALAPPKLSPPFPCLAQSASRAAGARRALSASRGRRGLLGSGSLALPLP 326
             RG P   P +  P     + +  RAA A   L A    R   G  +   P P
Sbjct: 181 RLRGEPKTPPGRSGPSGGVRSGAGHRAATAEHQLGAGFSVRNGPGPPARLPPAP 234


>gi|40789265 beta 1,4-N-acetylgalactosaminyltransferase-transferase
           4 [Homo sapiens]
          Length = 1039

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 62/200 (31%), Positives = 75/200 (37%), Gaps = 46/200 (23%)

Query: 109 APHPTPASYPQGTISPPQLPAPRPKRFGGKQRPLWRIRGWETTVARLPEPRVGKLGKGPP 168
           +P P   + P  T++PP  P PR    GG  R   R   W    AR P P    LG+ PP
Sbjct: 461 SPAPAAPAQPGATLAPPTPPRPRD---GGTPRHS-RALSWAARAAR-PLPLF--LGRAPP 513

Query: 169 PRPA---PPG----TRCCPGARAAQLLREAAAAAQGLRAPAARLPEPTRRAPGRPGCLPT 221
           PRPA   PP     TR  PG RA+             RAPA R P P       PG    
Sbjct: 514 PRPAVEQPPPKVYVTRVRPGQRASP------------RAPAPRAPWPP-----FPGVF-- 554

Query: 222 AAAAAADALWRSRRAPLPPTEFLSPRRTRPRKHPERTRRP-AQRLESGCRGHCSRGAPAL 280
                          PLP  +  +P R  PR H  RT  P A +     R   ++G    
Sbjct: 555 -----------LHPRPLPRVQLRAPPRP-PRPHGRRTGGPQATQPRPPARAQATQGGREG 602

Query: 281 APPKLSPPFPCLAQSASRAA 300
               L P  P +  + S  A
Sbjct: 603 QARTLGPAAPTVDSNLSSEA 622



 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 47/169 (27%), Positives = 61/169 (36%), Gaps = 24/169 (14%)

Query: 58  LQARTPAPPRERGESSSPRGPTLRGR--AKTTRGRSQGAGATETSAGNSAATAAPHPTPA 115
           L+    APPR   +S +P  P   G   A  T  R +  G    S   S A  A  P P 
Sbjct: 447 LEPTEAAPPRSGPQSPAPAAPAQPGATLAPPTPPRPRDGGTPRHSRALSWAARAARPLPL 506

Query: 116 SYPQGTISPPQLPAPRPKRFGGKQRPLWRIRGWETTVARLPEPR---------------V 160
              +     P +  P PK +      + R+R  +    R P PR               +
Sbjct: 507 FLGRAPPPRPAVEQPPPKVY------VTRVRPGQRASPRAPAPRAPWPPFPGVFLHPRPL 560

Query: 161 GKLGKGPPPRPAPPGTRCCPGARAAQLLREA-AAAAQGLRAPAARLPEP 208
            ++    PPRP  P  R   G +A Q    A A A QG R   AR   P
Sbjct: 561 PRVQLRAPPRPPRPHGRRTGGPQATQPRPPARAQATQGGREGQARTLGP 609


>gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens]
          Length = 2303

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 68/249 (27%), Positives = 87/249 (34%), Gaps = 33/249 (13%)

Query: 60   ARTPAPPRERGESSSPRGPTLRGR----AKTTRGRSQGAGATETSAGNSAATAAPHP--- 112
            AR    P  RG + +  GP  RG      +     S G+ +++ S      T        
Sbjct: 1945 ARAVPEPGPRGRAGTEAGPGARGGRLGLVRVASALSSGSESSDRSGFRRQLTFIKESPGL 2004

Query: 113  ----TPASYPQGTISPPQLPAPRPKRFGGKQRPLWRIRGWETTVARLPEPRVGKLGKGPP 168
                +  S  +   S PQ  +PR  R       L   R  E   A    PR G      P
Sbjct: 2005 RRRRSELSSAESAASAPQGASPRRGRPALPAVFLCSSRCEELRAA----PRQGPA----P 2056

Query: 169  PRPAPPGTRCCPGARAAQLLREAAAAAQGLRAPAARLPEPTRRAPGRP---------GCL 219
             R  PP  R  PG R A+     + +   +RAPAAR PE  +R    P         G +
Sbjct: 2057 ARQRPPAARPSPGERPARRTTSESPSRLPVRAPAAR-PETVKRYASLPHISVARRPDGAV 2115

Query: 220  PTAAAAAADALWRSRRAPLPPTEFLSP----RRTRPRKHPERTRRPAQRLESGCRGHCSR 275
            P A A+A  A   S   P P     +P    RR R    P   R          RG    
Sbjct: 2116 PAAPASADAARRSSDGEPRPLPRVAAPGTTWRRIRDEDVPHILRSTLPATALPLRGSTPE 2175

Query: 276  GAPALAPPK 284
             APA  PP+
Sbjct: 2176 DAPAGPPPR 2184



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 86/327 (26%), Positives = 120/327 (36%), Gaps = 71/327 (21%)

Query: 44   KRSSGQAGNKSERELQARTPAPPRERGESSSPRGPTL-RGRAKTTRGRSQGAGATETSAG 102
            +++ G+ G  S R  + R  A  +  G   SP GP   RG  KTT G             
Sbjct: 1739 RQAEGEMG--SARRPEKRGAASVKTSGSPRSPAGPEKPRGTQKTTPG-------VPAVLR 1789

Query: 103  NSAATAAPHPTPASYPQGT---------ISPP---QLPAPRPKRFGGKQRPLWRIRGWET 150
                   P P P + P+GT         ++PP   Q  AP      G+QR     R  +T
Sbjct: 1790 GRTVIYVPSPAPRAQPKGTPGPRATPRKVAPPCLAQPAAPAKVPSPGQQRSRSLHRPAKT 1849

Query: 151  T-VARLPEPRVGKLGKGPPPRPAPPGTRCCPGARAAQLLREAAAAAQGLRAPAARLPEPT 209
            + +A L +          PPR A P  R          L +  +++    +PA++ P P 
Sbjct: 1850 SELATLSQ----------PPRSATPPAR----------LAKTPSSSSSQTSPASQ-PLPR 1888

Query: 210  RRAPGRPGCLPTAAAAAADALWRSRRAPLPPTEFLSPRRTRPRKHPERTRRPAQRLESGC 269
            +R P            AA AL     +P+P T    P RT   K   +T+R   R+    
Sbjct: 1889 KRPP---------VTQAAGALPGPGASPVPKT----PARTLLAKQ-HKTQRSPVRIPFMQ 1934

Query: 270  RGHCSRGAPAL--APPKLSPPFPCLAQSASRAAGARRAL----------SASRGRRGLLG 317
            R    RG P L  A P+  P      ++   A G R  L          S S  R G   
Sbjct: 1935 R-PARRGPPPLARAVPEPGPRGRAGTEAGPGARGGRLGLVRVASALSSGSESSDRSGFRR 1993

Query: 318  SGSLALPLPGCREPRQRLHGSDGAAGA 344
              +     PG R  R  L  ++ AA A
Sbjct: 1994 QLTFIKESPGLRRRRSELSSAESAASA 2020


>gi|23510413 sorting nexin 26 [Homo sapiens]
          Length = 1126

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 88/338 (26%), Positives = 128/338 (37%), Gaps = 52/338 (15%)

Query: 3   SVSGSDPQV----LEEHPSRKLGRYRSPT-PLRPAKGKTICTRFGDKRSSGQA--GNKSE 55
           S++GS P      LEE  +R  GR  +PT P  P    +   R   +R   Q   G  S 
Sbjct: 532 SLAGSCPSTRLLTLEEAQARTQGRLGTPTEPTTPKAPASPAERRKGERGEKQRKPGGSSW 591

Query: 56  RELQA--RTPAPPRER-----GESSSPRGP--------TLRGRAKTTRGRSQGAGATETS 100
           +   A  R P+ PR++     G + +P  P        TLR         SQ +GA    
Sbjct: 592 KTFFALGRGPSVPRKKPLPWLGGTRAPPQPSGSRPDTVTLRSAKSEESLSSQASGAELLG 651

Query: 101 AGNSAATAAPHPTPASYPQGTISPPQLP-----APRPKRFGGKQRPLWRIRGWETTV--- 152
           AG + A+A   PTPA  P  ++ P  +P     A  P     +Q    ++RG +  +   
Sbjct: 652 AGGAPASAT--PTPALSPGRSLRPHLIPLLLRGAEAPLTDACQQEMCSKLRGAQGPLGPD 709

Query: 153 --ARLPEPRVGKL--GKGPPPRPAPPG--TRCCPGARAAQLLREAAAAAQGLRAPAARLP 206
             + LP P +  L  G  PPP P  P          RA Q+  + +    G   PA++ P
Sbjct: 710 MESPLPPPPLSLLRPGGAPPPPPKNPARLMALALAERAQQVAEQQSQQECGGTPPASQSP 769

Query: 207 -------EPTRRAPGRPGCLPTAAAAAADALWRSRRAPLPPTEFLSPRRTRPRKHPERTR 259
                  E      G  G  P   + A    W     P  P +       R ++    +R
Sbjct: 770 FHRSLSLEVGGEPLGTSGSGPPPNSLAHPGAWVPGPPPYLPRQQSDGSLLRSQRPMGTSR 829

Query: 260 R----PAQ---RLESGCRGHCSRGAPALAPPKLSPPFP 290
           R    PAQ   +L +G  G  +  A A +P  +    P
Sbjct: 830 RGLRGPAQVSAQLRAGGGGRDAPEAAAQSPCSVPSQVP 867


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
           sapiens]
          Length = 1487

 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 87/334 (26%), Positives = 110/334 (32%), Gaps = 50/334 (14%)

Query: 26  PTPLRPAKGKTICTRFGDKRSSGQAGNKSERELQARTPAPPRERGESSSPRGPTLRGRAK 85
           P P  PA  +      GDK   G  G +  R+ +  TP  P   G    P  P L G   
Sbjct: 122 PGPQGPAGEQGPRGDRGDKGEKGAPGPRG-RDGEPGTPGNPGPPGPPGPPGPPGLGGNFA 180

Query: 86  TTRGRSQGAGATETSAGNSAATAAPHPTPASYPQGTISPPQLPAPRPKRFGGKQRPLWRI 145
                +Q AG  +  AG +       P     P+G   P   P P+              
Sbjct: 181 -----AQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQ-------------- 221

Query: 146 RGWETTVARLPEPRV-GKLG-KGPPPRPAPPGTRCCPGARAAQLLREAAAAAQGLRAPAA 203
            G++       EP V G +G +GPP  P  PG     G       +   A  +G   P  
Sbjct: 222 -GFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAG-------KPGKAGERGPPGPQG 273

Query: 204 RLPEPTRRAPGRPGCLPTAAAAAADALWRSRRAPL------PPTEFLSPRRTRPRKHPER 257
               P    PG PG          D       AP        P E  SP    PR  P  
Sbjct: 274 ARGFPG--TPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGE 331

Query: 258 TRRPAQRLESGCRGHCSRGAPALAP----PKLSPPFPCLAQSASRAAG--ARRALSASRG 311
             R      +G RG+  +  PA  P    P   P FP  A  A   AG    R    ++G
Sbjct: 332 RGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPG-APGAKGEAGPTGARGPEGAQG 390

Query: 312 RRGLLGSGSLALPLPGCREPRQRLHGSDGAAGAR 345
            RG  G+     P      P     G+DG  GA+
Sbjct: 391 PRGEPGTPGSPGPAGASGNP-----GTDGIPGAK 419



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 84/327 (25%), Positives = 103/327 (31%), Gaps = 81/327 (24%)

Query: 42   GDKRSSGQAGNKSERELQARTPAPPRERGE--------SSSPRGPT----LRGRAKTTRG 89
            G +  SG  G   E  LQ     PP E+GE        +  P GP      RG       
Sbjct: 930  GARGDSGPPGRAGEPGLQGPA-GPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQ 988

Query: 90   RSQ-GAGATETSAGNSAATAAPHPTPASYPQGTISPPQLPAPRPKRFGGKQRPLWRIRGW 148
            R + G       +G      AP  +    P G + PP L  P                  
Sbjct: 989  RGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGP------------------ 1030

Query: 149  ETTVARLPEPRVGKLGKGPPPRPAPPGTRCCPGARAAQLLREAAAAAQGLRAPAARLPEP 208
                             G P R   PG    PG       R+ AA  +G R     +  P
Sbjct: 1031 ----------------AGEPGREGSPGADGPPG-------RDGAAGVKGDRGETGAVGAP 1067

Query: 209  TRRAPGRPGCLPTAAAAA--ADALWRSRRAPLPPTEFLSPRRTR----PRKHPERTRRPA 262
               APG PG    A       D      + P+ P+     R  +    PR        P 
Sbjct: 1068 --GAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPG 1125

Query: 263  QRLESGCRGHCS-RGAPALAPPKLSPPFPCLAQSASRAAGARRALSASRGRRGLLG---- 317
            +R   G RG    +G P        PP P   Q AS  AG     S  RG  G +G    
Sbjct: 1126 ERGLKGHRGFTGLQGLP-------GPPGPSGDQGASGPAGP----SGPRGPPGPVGPSGK 1174

Query: 318  SGSLALPLP-GCREPRQRLHGSDGAAG 343
             G+  +P P G   PR R  G  G AG
Sbjct: 1175 DGANGIPGPIGPPGPRGR-SGETGPAG 1200



 Score = 33.9 bits (76), Expect = 0.22
 Identities = 81/324 (25%), Positives = 101/324 (31%), Gaps = 51/324 (15%)

Query: 42  GDKRSSGQAGNKSERELQARTPAPPRERGESSSPRGPTLRGRAKTTRGRS--QGAGATET 99
           GD   +G+ G   ER        PP  +G    P  P L G  K  RG     GA     
Sbjct: 252 GDDGEAGKPGKAGER-------GPPGPQGARGFPGTPGLPG-VKGHRGYPGLDGAKGEAG 303

Query: 100 SAGNSAATAAPHPTPASYPQGTISPPQLPAPRPKRFGGKQRPLWRIRGWETTVARLPEPR 159
           + G    + +P    +  P G   P  LP  R +                T  A     R
Sbjct: 304 APGVKGESGSPGENGSPGPMG---PRGLPGERGR----------------TGPAGAAGAR 344

Query: 160 VGKLGKGPPPRPAPPGTRCCPGARAAQLLREAAAAAQGLRAP-AARLPEPTRRAPGRPGC 218
                 GP   P P G    PG   A   +   A   G R P  A+ P      PG PG 
Sbjct: 345 GNDGQPGPAGPPGPVGPAGGPGFPGAPGAK-GEAGPTGARGPEGAQGPRGEPGTPGSPGP 403

Query: 219 LPTAAAAAADALWRSRRAPLPPTEFLSPRRTRPR--KHPERTRRP----AQRLESGCRGH 272
              +     D +  ++ +   P    +P    PR    P+    P     Q  E G  G 
Sbjct: 404 AGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGF 463

Query: 273 CSRGAPALAPPKLSP---PFPCLAQSASRAAGARRALS--------ASRGRRGLLGSGSL 321
                P   P    P   P P   +    A G    +          + G RG  G   L
Sbjct: 464 KGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGL 523

Query: 322 ALP--LPGCREPRQRLHGSDGAAG 343
           A P   PG R P   L G  GA G
Sbjct: 524 AGPKGAPGERGP-SGLAGPKGANG 546



 Score = 33.9 bits (76), Expect = 0.22
 Identities = 86/335 (25%), Positives = 103/335 (30%), Gaps = 71/335 (21%)

Query: 66  PRERGESSSPRGPTLRGR-AKTTRGRSQGAGATETSAGNSAATAAPHPT-------PASY 117
           P + GE   P  P LRG   K     + G       AG      AP P+       P   
Sbjct: 614 PGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGP 673

Query: 118 P-----------QGTISPPQLPAPRPKR-FGGKQ-----RPLWRIRGWETTVARLPEPRV 160
           P            G    P L  PR +R F G++     + L   RG   T      P+ 
Sbjct: 674 PGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGT-DGPKG 732

Query: 161 GKLGKGPPPRPAPPGTRCCPGARAAQLLR--------------EAAAAAQGLRAPAARLP 206
                GPP    PPG +  PG R A  +               E A    G R     + 
Sbjct: 733 ASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIG 792

Query: 207 EP-------TRRAPGRPGCLPTAAAAAADALWRSRRAPLPPTEFLSPRRTRPRKHPERTR 259
            P        +   G PG   +A A  A    R    P  P  F  P        P    
Sbjct: 793 PPGPAGANGEKGEVGPPGPAGSAGARGAPG-ERGETGPPGPAGFAGP--------PGADG 843

Query: 260 RPAQRLESGCRGH-CSRGAPALAPPKLSPPFPCLAQSASRAAGARRA--------LSASR 310
           +P  + E G  G     GAP    P    P P      +   GAR A           + 
Sbjct: 844 QPGAKGEQGEAGQKGDAGAPGPQGPS-GAPGPQGPTGVTGPKGARGAQGPPGATGFPGAA 902

Query: 311 GRRGLLGSGSLALPLPGCREPRQRLHGSDGAAGAR 345
           GR G  GS     P PG   P     G DG  GAR
Sbjct: 903 GRVGPPGSNGNPGP-PGPPGP----SGKDGPKGAR 932



 Score = 32.3 bits (72), Expect = 0.64
 Identities = 41/159 (25%), Positives = 56/159 (35%), Gaps = 20/159 (12%)

Query: 25   SPTPLRPAKGKTICTRFGDKRSSGQAGNKSERELQARTPAPPR-ERGESSSPRGPTLRGR 83
            SP P  P   +      G +   G +G    R +Q   P  PR ++GE+  P    L+G 
Sbjct: 1075 SPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQG--PQGPRGDKGEAGEPGERGLKGH 1132

Query: 84   AKTTRGRSQGAGATETSAGNSAATAAPHPTPASYPQGTISPPQLPAPRPKRFGGKQRPLW 143
               T    QG       +G+  A+    P+    P G + P            G   P+ 
Sbjct: 1133 RGFTG--LQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGAN-----GIPGPIG 1185

Query: 144  RIRGWETTVARLPEPRVGKLGK-GPPPRPAPPGTRCCPG 181
                        P  R G+ G  GPP  P PPG    PG
Sbjct: 1186 PPG---------PRGRSGETGPAGPPGNPGPPGPPGPPG 1215



 Score = 28.5 bits (62), Expect = 9.2
 Identities = 69/260 (26%), Positives = 86/260 (33%), Gaps = 27/260 (10%)

Query: 104 SAATAAPHPTPASYPQGTISP---PQLPAPRPKRFGGKQRPLWRIRGWETTVARLPEPRV 160
           + A+  P P       G I     P+ P P P+   G+Q P           A  P  R 
Sbjct: 94  ATASGQPGPKGQKGEPGDIKDIVGPKGP-PGPQGPAGEQGPRGDRGDKGEKGAPGPRGRD 152

Query: 161 GKLGK----GPPPRPAPPGTRCCPGARAAQLLREAAAAAQGLRAPAARLPEPTRRAPGRP 216
           G+ G     GPP  P PPG     G  AAQ+       A G +    + P       G P
Sbjct: 153 GEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPP 212

Query: 217 GCLPTAAAAAADALWRSRRAPLPPTEFLSPRRTRPRKHPERTRRPAQRLESGCRGHC-SR 275
           G       A A      +  P  P E        PR  P    +P    E+G  G    R
Sbjct: 213 G------PAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGER 266

Query: 276 GAPALAPPKLSPPFPCLAQSASRAAGARRALSASRGRRGLLG-SGSLALP----LPGCRE 330
           G P     +  P  P L     +       L  ++G  G  G  G    P     PG   
Sbjct: 267 GPPGPQGARGFPGTPGL--PGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMG 324

Query: 331 PR-----QRLHGSDGAAGAR 345
           PR     +   G  GAAGAR
Sbjct: 325 PRGLPGERGRTGPAGAAGAR 344


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 1418

 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 87/334 (26%), Positives = 110/334 (32%), Gaps = 50/334 (14%)

Query: 26  PTPLRPAKGKTICTRFGDKRSSGQAGNKSERELQARTPAPPRERGESSSPRGPTLRGRAK 85
           P P  PA  +      GDK   G  G +  R+ +  TP  P   G    P  P L G   
Sbjct: 53  PGPQGPAGEQGPRGDRGDKGEKGAPGPRG-RDGEPGTPGNPGPPGPPGPPGPPGLGGNFA 111

Query: 86  TTRGRSQGAGATETSAGNSAATAAPHPTPASYPQGTISPPQLPAPRPKRFGGKQRPLWRI 145
                +Q AG  +  AG +       P     P+G   P   P P+              
Sbjct: 112 -----AQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQ-------------- 152

Query: 146 RGWETTVARLPEPRV-GKLG-KGPPPRPAPPGTRCCPGARAAQLLREAAAAAQGLRAPAA 203
            G++       EP V G +G +GPP  P  PG     G       +   A  +G   P  
Sbjct: 153 -GFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAG-------KPGKAGERGPPGPQG 204

Query: 204 RLPEPTRRAPGRPGCLPTAAAAAADALWRSRRAPL------PPTEFLSPRRTRPRKHPER 257
               P    PG PG          D       AP        P E  SP    PR  P  
Sbjct: 205 ARGFPG--TPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGE 262

Query: 258 TRRPAQRLESGCRGHCSRGAPALAP----PKLSPPFPCLAQSASRAAG--ARRALSASRG 311
             R      +G RG+  +  PA  P    P   P FP  A  A   AG    R    ++G
Sbjct: 263 RGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPG-APGAKGEAGPTGARGPEGAQG 321

Query: 312 RRGLLGSGSLALPLPGCREPRQRLHGSDGAAGAR 345
            RG  G+     P      P     G+DG  GA+
Sbjct: 322 PRGEPGTPGSPGPAGASGNP-----GTDGIPGAK 350



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 84/327 (25%), Positives = 103/327 (31%), Gaps = 81/327 (24%)

Query: 42   GDKRSSGQAGNKSERELQARTPAPPRERGE--------SSSPRGPT----LRGRAKTTRG 89
            G +  SG  G   E  LQ     PP E+GE        +  P GP      RG       
Sbjct: 861  GARGDSGPPGRAGEPGLQGPA-GPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQ 919

Query: 90   RSQ-GAGATETSAGNSAATAAPHPTPASYPQGTISPPQLPAPRPKRFGGKQRPLWRIRGW 148
            R + G       +G      AP  +    P G + PP L  P                  
Sbjct: 920  RGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGP------------------ 961

Query: 149  ETTVARLPEPRVGKLGKGPPPRPAPPGTRCCPGARAAQLLREAAAAAQGLRAPAARLPEP 208
                             G P R   PG    PG       R+ AA  +G R     +  P
Sbjct: 962  ----------------AGEPGREGSPGADGPPG-------RDGAAGVKGDRGETGAVGAP 998

Query: 209  TRRAPGRPGCLPTAAAAA--ADALWRSRRAPLPPTEFLSPRRTR----PRKHPERTRRPA 262
               APG PG    A       D      + P+ P+     R  +    PR        P 
Sbjct: 999  --GAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPG 1056

Query: 263  QRLESGCRGHCS-RGAPALAPPKLSPPFPCLAQSASRAAGARRALSASRGRRGLLG---- 317
            +R   G RG    +G P        PP P   Q AS  AG     S  RG  G +G    
Sbjct: 1057 ERGLKGHRGFTGLQGLP-------GPPGPSGDQGASGPAGP----SGPRGPPGPVGPSGK 1105

Query: 318  SGSLALPLP-GCREPRQRLHGSDGAAG 343
             G+  +P P G   PR R  G  G AG
Sbjct: 1106 DGANGIPGPIGPPGPRGR-SGETGPAG 1131



 Score = 33.9 bits (76), Expect = 0.22
 Identities = 81/324 (25%), Positives = 101/324 (31%), Gaps = 51/324 (15%)

Query: 42  GDKRSSGQAGNKSERELQARTPAPPRERGESSSPRGPTLRGRAKTTRGRS--QGAGATET 99
           GD   +G+ G   ER        PP  +G    P  P L G  K  RG     GA     
Sbjct: 183 GDDGEAGKPGKAGER-------GPPGPQGARGFPGTPGLPG-VKGHRGYPGLDGAKGEAG 234

Query: 100 SAGNSAATAAPHPTPASYPQGTISPPQLPAPRPKRFGGKQRPLWRIRGWETTVARLPEPR 159
           + G    + +P    +  P G   P  LP  R +                T  A     R
Sbjct: 235 APGVKGESGSPGENGSPGPMG---PRGLPGERGR----------------TGPAGAAGAR 275

Query: 160 VGKLGKGPPPRPAPPGTRCCPGARAAQLLREAAAAAQGLRAP-AARLPEPTRRAPGRPGC 218
                 GP   P P G    PG   A   +   A   G R P  A+ P      PG PG 
Sbjct: 276 GNDGQPGPAGPPGPVGPAGGPGFPGAPGAK-GEAGPTGARGPEGAQGPRGEPGTPGSPGP 334

Query: 219 LPTAAAAAADALWRSRRAPLPPTEFLSPRRTRPR--KHPERTRRP----AQRLESGCRGH 272
              +     D +  ++ +   P    +P    PR    P+    P     Q  E G  G 
Sbjct: 335 AGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGF 394

Query: 273 CSRGAPALAPPKLSP---PFPCLAQSASRAAGARRALS--------ASRGRRGLLGSGSL 321
                P   P    P   P P   +    A G    +          + G RG  G   L
Sbjct: 395 KGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGL 454

Query: 322 ALP--LPGCREPRQRLHGSDGAAG 343
           A P   PG R P   L G  GA G
Sbjct: 455 AGPKGAPGERGP-SGLAGPKGANG 477



 Score = 33.9 bits (76), Expect = 0.22
 Identities = 86/335 (25%), Positives = 103/335 (30%), Gaps = 71/335 (21%)

Query: 66  PRERGESSSPRGPTLRGR-AKTTRGRSQGAGATETSAGNSAATAAPHPT-------PASY 117
           P + GE   P  P LRG   K     + G       AG      AP P+       P   
Sbjct: 545 PGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGP 604

Query: 118 P-----------QGTISPPQLPAPRPKR-FGGKQ-----RPLWRIRGWETTVARLPEPRV 160
           P            G    P L  PR +R F G++     + L   RG   T      P+ 
Sbjct: 605 PGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGT-DGPKG 663

Query: 161 GKLGKGPPPRPAPPGTRCCPGARAAQLLR--------------EAAAAAQGLRAPAARLP 206
                GPP    PPG +  PG R A  +               E A    G R     + 
Sbjct: 664 ASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIG 723

Query: 207 EP-------TRRAPGRPGCLPTAAAAAADALWRSRRAPLPPTEFLSPRRTRPRKHPERTR 259
            P        +   G PG   +A A  A    R    P  P  F  P        P    
Sbjct: 724 PPGPAGANGEKGEVGPPGPAGSAGARGAPG-ERGETGPPGPAGFAGP--------PGADG 774

Query: 260 RPAQRLESGCRGH-CSRGAPALAPPKLSPPFPCLAQSASRAAGARRA--------LSASR 310
           +P  + E G  G     GAP    P    P P      +   GAR A           + 
Sbjct: 775 QPGAKGEQGEAGQKGDAGAPGPQGPS-GAPGPQGPTGVTGPKGARGAQGPPGATGFPGAA 833

Query: 311 GRRGLLGSGSLALPLPGCREPRQRLHGSDGAAGAR 345
           GR G  GS     P PG   P     G DG  GAR
Sbjct: 834 GRVGPPGSNGNPGP-PGPPGP----SGKDGPKGAR 863



 Score = 32.3 bits (72), Expect = 0.64
 Identities = 41/159 (25%), Positives = 56/159 (35%), Gaps = 20/159 (12%)

Query: 25   SPTPLRPAKGKTICTRFGDKRSSGQAGNKSERELQARTPAPPR-ERGESSSPRGPTLRGR 83
            SP P  P   +      G +   G +G    R +Q   P  PR ++GE+  P    L+G 
Sbjct: 1006 SPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQG--PQGPRGDKGEAGEPGERGLKGH 1063

Query: 84   AKTTRGRSQGAGATETSAGNSAATAAPHPTPASYPQGTISPPQLPAPRPKRFGGKQRPLW 143
               T    QG       +G+  A+    P+    P G + P            G   P+ 
Sbjct: 1064 RGFTG--LQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGAN-----GIPGPIG 1116

Query: 144  RIRGWETTVARLPEPRVGKLGK-GPPPRPAPPGTRCCPG 181
                        P  R G+ G  GPP  P PPG    PG
Sbjct: 1117 PPG---------PRGRSGETGPAGPPGNPGPPGPPGPPG 1146


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 67/229 (29%), Positives = 77/229 (33%), Gaps = 59/229 (25%)

Query: 104 SAATAAPHPTPASYPQGTISPPQLPAPRPKRFGGKQRPLWRIRGWETTVARLPEPRVGKL 163
           +AA AAP PTPA        PP  PAP                      AR P       
Sbjct: 121 AAAAAAPPPTPA--------PPPPPAPVA----------------AAAPARAPRAAAAAA 156

Query: 164 GKGPPPRPAPPGTRCCPGARAAQLLREAAAAAQGLRAPAARLPEPTRRAPGRPGCLPTAA 223
              P P PA PG R     RAA L     A A     PA   P   RRAP      P A 
Sbjct: 157 TAPPSPGPAQPGPR---AQRAAPLAAPPPAPA---APPAVAPPAGPRRAP------PPAV 204

Query: 224 AAAADALWRSRRAPLPPTEFLSPRRTRPRKHPERTRRPAQRLESGCRGHCSRGAPALAPP 283
           AA        R  PLPP         +P   P++ + P  + +    G   R   A  P 
Sbjct: 205 AA--------REPPLPPP-------PQPPAPPQQQQPPPPQPQPPPEGGAVRAGGAARPV 249

Query: 284 KLSPPFPCLAQSA--------SRAAGARRALSASRGRRGLLGSGSLALP 324
            L      L  S          R  G     +A+RGR      G+LALP
Sbjct: 250 SLREVVRYLGGSGGAGGRLTRGRVQGLLEEEAAARGRLERTRLGALALP 298



 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 58/211 (27%), Positives = 77/211 (36%), Gaps = 27/211 (12%)

Query: 63  PAPPRERGESSSPRGPTLRGRAKTTRGRSQGAGATETSAGNSAATAAPHPTPASYPQGTI 122
           P PP     +++P        A  T   S G       A  +A  AAP P PA+ P   +
Sbjct: 133 PPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPP--AV 190

Query: 123 SPPQLPAPRPKRFGGKQRPLWRIRGWETTVARLPEPRV-GKLGKGPPPRPAPP---GTRC 178
           +PP          G ++ P   +   E  +   P+P    +  + PPP+P PP   G   
Sbjct: 191 APPA---------GPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPPEGGAVR 241

Query: 179 CPGARAAQLLREAAAAAQGLRAPAARLPEPTRRAPGRPGCLPTAAAAAADALWRSRRAPL 238
             GA     LRE      G      RL        GR   L    AAA   L R+R   L
Sbjct: 242 AGGAARPVSLREVVRYLGGSGGAGGRLTR------GRVQGLLEEEAAARGRLERTRLGAL 295

Query: 239 PPTEFLSPRRTRP-RKHPERTRRPAQRLESG 268
                  PR  RP R  P  + RP++    G
Sbjct: 296 -----ALPRGDRPGRAPPAASARPSRSKRGG 321



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 84/289 (29%), Positives = 103/289 (35%), Gaps = 71/289 (24%)

Query: 94  AGATETSAGNSAATAAPH------PTPASYPQGTISPP---------QLPAPRPKRFGGK 138
           A A  T+A  S++ A+PH       T  S       P          +   P P+R   +
Sbjct: 13  AAAATTAAAASSSAASPHYQEWILDTIDSLRSRKARPDLERICRMVRRRHGPEPERTRAE 72

Query: 139 ------QRPLWRIRGWETTVARLPEPRVGKLGKGPPPRPAPPGTRCCPGARAAQLLREAA 192
                 QR + R+  ++ +++     RV    +G  P PAPP  R   GA AA     AA
Sbjct: 73  LEKLIQQRAVLRV-SYKGSISYRNAARVQPPRRGATP-PAPP--RAPRGAPAAA----AA 124

Query: 193 AAAQGLRAPAARLPEPTRRAPGRPGCLPTAAAAAADA----------LWRSRRAPL--PP 240
           AA     AP    P P   A   P   P AAAAAA A              R APL  PP
Sbjct: 125 AAPPPTPAPP---PPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPP 181

Query: 241 TEFLSPRRTRPRKHPERTRRPAQRLESGCRGHCSRGAPALAPPKLSP------------P 288
               +P    P   P R   PA           +   P L PP   P            P
Sbjct: 182 PAPAAPPAVAPPAGPRRAPPPA----------VAAREPPLPPPPQPPAPPQQQQPPPPQP 231

Query: 289 FPCLAQSASRAAGARRALSASRGRRGLLGSGSLALPLPGCREPRQRLHG 337
            P     A RA GA R +S     R L GSG       G R  R R+ G
Sbjct: 232 QPPPEGGAVRAGGAARPVSLREVVRYLGGSGG-----AGGRLTRGRVQG 275


>gi|239740948 PREDICTED: hypothetical protein LOC644246 [Homo
           sapiens]
          Length = 328

 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 79/278 (28%), Positives = 96/278 (34%), Gaps = 63/278 (22%)

Query: 62  TPAPPRERGESSSPRG--------PTLRGRAKTTRGRSQGAGATETSAGNSAATAAPHPT 113
           TP+P  ++G    P          P L   A T R   +G G  E   G           
Sbjct: 66  TPSPDPQQGSPERPFKVPGVFSTLPCL-STALTFRAGGRGRGGGEGGGGERLLFLLFRAL 124

Query: 114 --PASYPQGTISPPQLPAPRPKRFGGKQRPLWRIRGWETTVARLPEPRVGK---LGKGPP 168
             P S P G   P     P+P R GG+        G E+  A  P PR  K   L   P 
Sbjct: 125 SRPCSAPTG---PEHGWRPQPGREGGRA-------GAESETA--PPPRTNKHRRLQPEPA 172

Query: 169 PRPAPPGTRCCPGARAAQLLREAAAAAQGLRAPAARLPEPTRR---APGRPGCLPTAAAA 225
           PRP PP     PG+               L+ P    P P RR   A  R   LP A  A
Sbjct: 173 PRPPPPAASFQPGS--------------ALQPP----PAPPRRDDSASLRCSVLPPARRA 214

Query: 226 AADAL--WRSRRAPLPP----------TEFLSPRRTRPRKHPERTRRPAQRLESGCRGHC 273
            A AL  WR     LPP          +E    RR +  +  +R RR   R   G  G  
Sbjct: 215 VAAALGKWRPSSFSLPPFNLKRRENGASERAGERRGQGEEGQQRLRRLRLRRPRGPPGGA 274

Query: 274 SRGAPALAPPKLSPPFPCLAQSASRAAGARRALSASRG 311
           +  A  +AP +      C   S     GAR  L  + G
Sbjct: 275 AAAASVMAPRRSR----CFCTSICGGRGARPQLPRTCG 308


>gi|182507165 thymus expressed gene 3-like [Homo sapiens]
          Length = 629

 Score = 48.5 bits (114), Expect = 9e-06
 Identities = 72/259 (27%), Positives = 95/259 (36%), Gaps = 54/259 (20%)

Query: 61  RTPAP---PRERGESSSPRGPTLRG--RAKTTRGRSQGAGATETSAGNSAA------TAA 109
           R+P P   P      +   G  L G   A   R R +GAG   TS G +        +  
Sbjct: 227 RSPRPCGRPPTDSPDAGGAGRPLDGYISALLRRRRRRGAGQPRTSPGGADGGPRRQNSVR 286

Query: 110 PHPTPASYPQGTISPPQLPAPRPKRFGGKQR-PLWRIRGWETT--VARLPEPRVGKLGKG 166
             P  AS   G+  P + P+   +R GG    P    R W ++      PEP        
Sbjct: 287 QRPPDASPSPGSARPAREPSL--ERVGGHPTSPAALSRAWASSWESEAAPEPAA------ 338

Query: 167 PPPRPAPPGTRCCPGARAAQLLREAAAAAQGLRAPAARLPEP--TR-------------R 211
           PP  P+PP +        AQ +  A AA +GL   AAR   P  TR             R
Sbjct: 339 PPAAPSPPDSPAEGRLVKAQYIPGAQAATRGLPGRAARRKPPPLTRGRSVEQSPPRERPR 398

Query: 212 APGRPGCLPTAAA--------------AAADALWRSRRAPLPPTEFLSPRRTRPRKHPER 257
           A GR G +  A+               +    L R+   P  P ++ +  R  PR  P R
Sbjct: 399 AAGRRGRMAEASGRRGSPRARKASRSQSETSLLGRASAVPSGPPKYPTAEREEPR--PPR 456

Query: 258 TRR-PAQRLESGCRGHCSR 275
            RR PA  L +   G C R
Sbjct: 457 PRRGPAPTLAAQAAGSCRR 475



 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 97/375 (25%), Positives = 128/375 (34%), Gaps = 82/375 (21%)

Query: 12  LEEHPSRKLGRYRSPTPLR--PAKGKTIC--TRFGDKRSSGQAGNKSERELQARTPAPPR 67
           LE+   R  G Y  P+      +   T C  + F    S G+ G    R + A     P+
Sbjct: 107 LEQESGRSSGFYEDPSSTGGPDSPPSTFCGDSGFSGSSSYGRLGPSEPRGIYASER--PK 164

Query: 68  ERGESSSPRGPTLRGRAKTTRGRSQ-------GAGATETSAGNSAATAAPHPTPASYPQG 120
             G++S      +  RA   R  S         AG    S+    A A P  TP+     
Sbjct: 165 SLGDASPSAPEVVGARAAVPRSFSAPYPTAGGSAGPEACSSAERRARAGPFLTPSPLHAV 224

Query: 121 TISPPQLPAPRPKR----FGGKQRPLWRIRGWETTVAR------LPEPRVGKLGKGPPPR 170
            +  P+ P  RP       GG  RPL    G+ + + R        +PR    G    PR
Sbjct: 225 AMRSPR-PCGRPPTDSPDAGGAGRPL---DGYISALLRRRRRRGAGQPRTSPGGADGGPR 280

Query: 171 ------PAPPGTRCCPG----ARAAQLLR-------------------EAAAAAQGLRAP 201
                   PP     PG    AR   L R                   E+ AA +    P
Sbjct: 281 RQNSVRQRPPDASPSPGSARPAREPSLERVGGHPTSPAALSRAWASSWESEAAPEPAAPP 340

Query: 202 AARLPEPTRRAPGR---PGCLPTAAAAAADALWRS-RRAPLPPTEFLSPRRTRPRKHPER 257
           AA  P P   A GR      +P A AA      R+ RR P P T   S  ++ PR+ P  
Sbjct: 341 AAPSP-PDSPAEGRLVKAQYIPGAQAATRGLPGRAARRKPPPLTRGRSVEQSPPRERPRA 399

Query: 258 TRRPAQRLESGCRGHCSRGAPALAPPKLSPPFPCLAQSASRAAGARRALSASRGRRGLLG 317
             R  +  E+  R    RG+P              A+ ASR+      L    GR   + 
Sbjct: 400 AGRRGRMAEASGR----RGSPR-------------ARKASRSQSETSLL----GRASAVP 438

Query: 318 SGSLALPLPGCREPR 332
           SG    P     EPR
Sbjct: 439 SGPPKYPTAEREEPR 453



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 58/221 (26%), Positives = 78/221 (35%), Gaps = 40/221 (18%)

Query: 28  PLRPAKGKTICTRFGDKRSSGQAGNKSERELQARTPAPPRERGESSSPRGPTLRGRAKTT 87
           P  PA+G+ +  ++       QA  +      AR   PP  RG S     P  R RA   
Sbjct: 346 PDSPAEGRLVKAQY---IPGAQAATRGLPGRAARRKPPPLTRGRSVEQSPPRERPRAAGR 402

Query: 88  RGRSQGAGATETSAGNSAATAAPHPTP-----ASYPQGTISPPQLPAPRPKRFGGKQRPL 142
           RGR   A     S     A+ +   T      ++ P G   PP+ P              
Sbjct: 403 RGRMAEASGRRGSPRARKASRSQSETSLLGRASAVPSG---PPKYPT------------- 446

Query: 143 WRIRGWETTVARLPEPRVGKLGKGPPPRPAPPGTRCCPGARAAQLLREAAAAAQGLRAPA 202
                     A   EPR  +  +GP P  A      C   R+   +  A       RAPA
Sbjct: 447 ----------AEREEPRPPRPRRGPAPTLAAQAAGSCRRWRSTAEIDAADGRRVRPRAPA 496

Query: 203 ARL--PEPTRRAPGRP---GCLPTAAAAAADALW-RSRRAP 237
           AR+  P P+  AP R    GC  + +  +A  L    RR P
Sbjct: 497 ARVPGPGPSPSAPQRRLLYGCAGSDSECSAGRLGPLGRRGP 537


>gi|239754657 PREDICTED: hypothetical protein XP_002346062 [Homo
           sapiens]
          Length = 384

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 79/275 (28%), Positives = 102/275 (37%), Gaps = 51/275 (18%)

Query: 82  GRAKTTRGRS----QGAGATETSAGNSAATAAPHPTPASYPQGTISPPQLPAPRPKRFGG 137
           G  + TR R     +G  + E++AG   +  APHP   + P       + P PR +   G
Sbjct: 42  GTCRLTRSRKSRLERGTFSPESAAGTEVS-GAPHPDSRTRPAA-----RPPHPRTRSPPG 95

Query: 138 KQRPLWRIRGWETTVARLPEPRVGKLGKGPPPRPAPPGTR-CCPGARAAQLLREAAAAAQ 196
           +        G  TT + +P PR  +   G   RPA PG R  C  ARA+     A AA Q
Sbjct: 96  RS-------GSGTTFSAVP-PRPSQHQSGSRLRPAAPGPRPGCSSARAS----PAPAAPQ 143

Query: 197 GLRAPAARLPEPTRRAPGRPGCLPTAAAAAADALWR--SRRAPLPPTEFLSPRRTRPRKH 254
                AA    P R A G  G  P +    +D +    SR    PP       R  PR+ 
Sbjct: 144 -----AAARTAPGRAASGGSG--PGSRGQGSDQVGARPSRAGGQPPPLTCRRCRAAPRRS 196

Query: 255 PERTRRPAQRLES---------GCRGHCSRGAPALAPPKL-SPPFPCLAQSASRAAGARR 304
               RRP   L+S          C    S G P  A     S  F   +       G   
Sbjct: 197 ARPFRRPGLPLKSRPGSGTGARSCGTWGSGGGPGTAAASSPSADFSSDSPQPIIIFGGAL 256

Query: 305 ALSASRGRRGLLGSGSLALPLPGCR-----EPRQR 334
            +    GRR   G G+     PGCR      PR+R
Sbjct: 257 RVRGCGGRRRSNGQGT----QPGCRLLSPAPPRRR 287



 Score = 30.4 bits (67), Expect = 2.4
 Identities = 80/309 (25%), Positives = 106/309 (34%), Gaps = 64/309 (20%)

Query: 5   SGSDPQVLEEHPSRKLGRYRSPTPLRPAKGKTICTRFGDKRSSGQAGNKSERELQARTPA 64
           S + P     HP     R RSP P R   G T  +    + S  Q+G++    L+   P 
Sbjct: 77  SRTRPAARPPHP-----RTRSP-PGRSGSGTTF-SAVPPRPSQHQSGSR----LRPAAPG 125

Query: 65  P-PRERGESSSPRGPTLRGRAKTTRGR---------SQGAGATETSAGNSAATAAPHPTP 114
           P P      +SP     +  A+T  GR         S+G G+ +  A  S A   P P  
Sbjct: 126 PRPGCSSARASPAPAAPQAAARTAPGRAASGGSGPGSRGQGSDQVGARPSRAGGQPPPLT 185

Query: 115 A----SYPQGTISP---PQLP-APRP-KRFGGKQRPLWRIRGWETTVARLPEPRVGKLGK 165
                + P+ +  P   P LP   RP    G +    W   G   T A    P       
Sbjct: 186 CRRCRAAPRRSARPFRRPGLPLKSRPGSGTGARSCGTWGSGGGPGTAA-ASSPSADFSSD 244

Query: 166 GPPPRPAPPG---TRCCPGARAAQLLREAAAAAQGLRAPAARL--PEPTRRAPGRPGCLP 220
            P P     G    R C G R +          QG + P  RL  P P RR   +P  L 
Sbjct: 245 SPQPIIIFGGALRVRGCGGRRRSN--------GQGTQ-PGCRLLSPAPPRRRYRKPLTLS 295

Query: 221 TAAAAAADALWRSRRAPLPPTEFLSPRRTRPRKHPERTRRPAQRLESGCRGHCSRGAPAL 280
                ++           P    ++PRR  PR  P        R  +G R H    AP  
Sbjct: 296 FGGGVSS-----------PTHPVVAPRRHFPRSVP--------RFPAGFRTHSLGTAPKP 336

Query: 281 APPKLSPPF 289
              K S P+
Sbjct: 337 KCWKHSQPW 345


>gi|239743279 PREDICTED: hypothetical protein XP_002342816 [Homo
           sapiens]
          Length = 384

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 79/275 (28%), Positives = 102/275 (37%), Gaps = 51/275 (18%)

Query: 82  GRAKTTRGRS----QGAGATETSAGNSAATAAPHPTPASYPQGTISPPQLPAPRPKRFGG 137
           G  + TR R     +G  + E++AG   +  APHP   + P       + P PR +   G
Sbjct: 42  GTCRLTRSRKSRLERGTFSPESAAGTEVS-GAPHPDSRTRPAA-----RPPHPRTRSPPG 95

Query: 138 KQRPLWRIRGWETTVARLPEPRVGKLGKGPPPRPAPPGTR-CCPGARAAQLLREAAAAAQ 196
           +        G  TT + +P PR  +   G   RPA PG R  C  ARA+     A AA Q
Sbjct: 96  RS-------GSGTTFSAVP-PRPSQHQSGSRLRPAAPGPRPGCSSARAS----PAPAAPQ 143

Query: 197 GLRAPAARLPEPTRRAPGRPGCLPTAAAAAADALWR--SRRAPLPPTEFLSPRRTRPRKH 254
                AA    P R A G  G  P +    +D +    SR    PP       R  PR+ 
Sbjct: 144 -----AAARTAPGRAASGGSG--PGSRGQGSDQVGARPSRAGGQPPPLTCRRCRAAPRRS 196

Query: 255 PERTRRPAQRLES---------GCRGHCSRGAPALAPPKL-SPPFPCLAQSASRAAGARR 304
               RRP   L+S          C    S G P  A     S  F   +       G   
Sbjct: 197 ARPFRRPGLPLKSRPGSGTGARSCGTWGSGGGPGTAAASSPSADFSSDSPQPIIIFGGAL 256

Query: 305 ALSASRGRRGLLGSGSLALPLPGCR-----EPRQR 334
            +    GRR   G G+     PGCR      PR+R
Sbjct: 257 RVRGCGGRRRSNGQGT----QPGCRLLSPAPPRRR 287



 Score = 30.4 bits (67), Expect = 2.4
 Identities = 80/309 (25%), Positives = 106/309 (34%), Gaps = 64/309 (20%)

Query: 5   SGSDPQVLEEHPSRKLGRYRSPTPLRPAKGKTICTRFGDKRSSGQAGNKSERELQARTPA 64
           S + P     HP     R RSP P R   G T  +    + S  Q+G++    L+   P 
Sbjct: 77  SRTRPAARPPHP-----RTRSP-PGRSGSGTTF-SAVPPRPSQHQSGSR----LRPAAPG 125

Query: 65  P-PRERGESSSPRGPTLRGRAKTTRGR---------SQGAGATETSAGNSAATAAPHPTP 114
           P P      +SP     +  A+T  GR         S+G G+ +  A  S A   P P  
Sbjct: 126 PRPGCSSARASPAPAAPQAAARTAPGRAASGGSGPGSRGQGSDQVGARPSRAGGQPPPLT 185

Query: 115 A----SYPQGTISP---PQLP-APRP-KRFGGKQRPLWRIRGWETTVARLPEPRVGKLGK 165
                + P+ +  P   P LP   RP    G +    W   G   T A    P       
Sbjct: 186 CRRCRAAPRRSARPFRRPGLPLKSRPGSGTGARSCGTWGSGGGPGTAA-ASSPSADFSSD 244

Query: 166 GPPPRPAPPG---TRCCPGARAAQLLREAAAAAQGLRAPAARL--PEPTRRAPGRPGCLP 220
            P P     G    R C G R +          QG + P  RL  P P RR   +P  L 
Sbjct: 245 SPQPIIIFGGALRVRGCGGRRRSN--------GQGTQ-PGCRLLSPAPPRRRYRKPLTLS 295

Query: 221 TAAAAAADALWRSRRAPLPPTEFLSPRRTRPRKHPERTRRPAQRLESGCRGHCSRGAPAL 280
                ++           P    ++PRR  PR  P        R  +G R H    AP  
Sbjct: 296 FGGGVSS-----------PTHPVVAPRRHFPRSVP--------RFPAGFRTHSLGTAPKP 336

Query: 281 APPKLSPPF 289
              K S P+
Sbjct: 337 KCWKHSQPW 345


>gi|239508962 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 384

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 79/275 (28%), Positives = 102/275 (37%), Gaps = 51/275 (18%)

Query: 82  GRAKTTRGRS----QGAGATETSAGNSAATAAPHPTPASYPQGTISPPQLPAPRPKRFGG 137
           G  + TR R     +G  + E++AG   +  APHP   + P       + P PR +   G
Sbjct: 42  GTCRLTRSRKSRLERGTFSPESAAGTEVS-GAPHPDSRTRPAA-----RPPHPRTRSPPG 95

Query: 138 KQRPLWRIRGWETTVARLPEPRVGKLGKGPPPRPAPPGTR-CCPGARAAQLLREAAAAAQ 196
           +        G  TT + +P PR  +   G   RPA PG R  C  ARA+     A AA Q
Sbjct: 96  RS-------GSGTTFSAVP-PRPSQHQSGSRLRPAAPGPRPGCSSARAS----PAPAAPQ 143

Query: 197 GLRAPAARLPEPTRRAPGRPGCLPTAAAAAADALWR--SRRAPLPPTEFLSPRRTRPRKH 254
                AA    P R A G  G  P +    +D +    SR    PP       R  PR+ 
Sbjct: 144 -----AAARTAPGRAASGGSG--PGSRGQGSDQVGARPSRAGGQPPPLTCRRCRAAPRRS 196

Query: 255 PERTRRPAQRLES---------GCRGHCSRGAPALAPPKL-SPPFPCLAQSASRAAGARR 304
               RRP   L+S          C    S G P  A     S  F   +       G   
Sbjct: 197 ARPFRRPGLPLKSRPGSGTGARSCGTWGSGGGPGTAAASSPSADFSSDSPQPIIIFGGAL 256

Query: 305 ALSASRGRRGLLGSGSLALPLPGCR-----EPRQR 334
            +    GRR   G G+     PGCR      PR+R
Sbjct: 257 RVRGCGGRRRSNGQGT----QPGCRLLSPAPPRRR 287



 Score = 30.4 bits (67), Expect = 2.4
 Identities = 80/309 (25%), Positives = 106/309 (34%), Gaps = 64/309 (20%)

Query: 5   SGSDPQVLEEHPSRKLGRYRSPTPLRPAKGKTICTRFGDKRSSGQAGNKSERELQARTPA 64
           S + P     HP     R RSP P R   G T  +    + S  Q+G++    L+   P 
Sbjct: 77  SRTRPAARPPHP-----RTRSP-PGRSGSGTTF-SAVPPRPSQHQSGSR----LRPAAPG 125

Query: 65  P-PRERGESSSPRGPTLRGRAKTTRGR---------SQGAGATETSAGNSAATAAPHPTP 114
           P P      +SP     +  A+T  GR         S+G G+ +  A  S A   P P  
Sbjct: 126 PRPGCSSARASPAPAAPQAAARTAPGRAASGGSGPGSRGQGSDQVGARPSRAGGQPPPLT 185

Query: 115 A----SYPQGTISP---PQLP-APRP-KRFGGKQRPLWRIRGWETTVARLPEPRVGKLGK 165
                + P+ +  P   P LP   RP    G +    W   G   T A    P       
Sbjct: 186 CRRCRAAPRRSARPFRRPGLPLKSRPGSGTGARSCGTWGSGGGPGTAA-ASSPSADFSSD 244

Query: 166 GPPPRPAPPG---TRCCPGARAAQLLREAAAAAQGLRAPAARL--PEPTRRAPGRPGCLP 220
            P P     G    R C G R +          QG + P  RL  P P RR   +P  L 
Sbjct: 245 SPQPIIIFGGALRVRGCGGRRRSN--------GQGTQ-PGCRLLSPAPPRRRYRKPLTLS 295

Query: 221 TAAAAAADALWRSRRAPLPPTEFLSPRRTRPRKHPERTRRPAQRLESGCRGHCSRGAPAL 280
                ++           P    ++PRR  PR  P        R  +G R H    AP  
Sbjct: 296 FGGGVSS-----------PTHPVVAPRRHFPRSVP--------RFPAGFRTHSLGTAPKP 336

Query: 281 APPKLSPPF 289
              K S P+
Sbjct: 337 KCWKHSQPW 345


>gi|188536004 zinc finger protein 469 [Homo sapiens]
          Length = 3925

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 57/211 (27%), Positives = 78/211 (36%), Gaps = 30/211 (14%)

Query: 61  RTPAPPRERGE------SSSPRGPTLRGRAKTTRGRSQGAGATETSAGNSAATAAPHPTP 114
           R   PP   G+      +SSP  P+       T       GA E + G + A   P   P
Sbjct: 7   RGAPPPTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGARE-AGGQAQAMELPEAQP 65

Query: 115 ASYPQGTISPPQL----PAPRPKRFGGKQRPLWRIRGWETTVARLPEPRVGKLGKGPPPR 170
                G + PP L    P+  P + G  Q P  R      +  + P    G+  +G PP+
Sbjct: 66  RQARDGELKPPSLRGQAPSSTPGKRGSPQTPPGR------SPLQAPSRLAGR-AEGSPPQ 118

Query: 171 PAPPGTRCCPGARAAQLLREAAAAAQGLRAPAARLPE------PTRRAPGRPGCLPTAAA 224
                 R   G  +++         +  +  AA+LPE      P   AP RPG   T A 
Sbjct: 119 ------RYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQ 172

Query: 225 AAADALWRSRRAPLPPTEFLSPRRTRPRKHP 255
            AA+ L   R    PP+ F S   T P   P
Sbjct: 173 PAAEELGFHRCFQEPPSSFTSTNYTSPSATP 203



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 59/222 (26%), Positives = 74/222 (33%), Gaps = 91/222 (40%)

Query: 71   ESSSPRGPTLRGRAKTTRGRSQGAGATETSAGNSAATAAPHPTPASYPQGTISPPQLPAP 130
            E S PRGP+                  ++ AG +  + AP P PA+ P      PQ P P
Sbjct: 872  EPSGPRGPS-------------SGHPLKSKAGVTPESKAPPPLPAATPD-----PQTPRP 913

Query: 131  RPKRFGGKQRPLWRIRGWETTVARLP----EPRVGK------------------------ 162
              +    + RP  R  G   T A  P    + R GK                        
Sbjct: 914  GDRGCPARGRPKTRSLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGG 973

Query: 163  ------------LGKGPPPRPAPPGTRCCPGARAAQLLREAAAAAQGLRAPAARLPEPTR 210
                        LG+ PPPRP  P T+  PG+RA    R   AAA         LPE TR
Sbjct: 974  RASGLRPRRNDGLGERPPPRPRRPRTQ-APGSRADPAPRVPRAAA---------LPEETR 1023

Query: 211  RAPGRPGCLPTAAAAAADALWRSRRAPLPPTEFLSPRRTRPR 252
                                  SRR  LPP +   PR+ + R
Sbjct: 1024 ---------------------SSRRRRLPPRK--DPRKRKAR 1042



 Score = 37.0 bits (84), Expect = 0.026
 Identities = 44/160 (27%), Positives = 58/160 (36%), Gaps = 19/160 (11%)

Query: 65  PPRERGESSSPRGPTLRGRAKTTRGRSQGAGATETSAGN-SAATAAPHPTPASYPQGTIS 123
           PP  +    S RGP      +   G++  A   +TS G      AAP P PA  PQ    
Sbjct: 384 PPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPPPARLPQ-LWD 442

Query: 124 PPQLPAPRPKR----------FGGKQRPLWRIRGWETTVARLPEPRVGKLGKGPPPRPAP 173
           P   P P P            F G+  P  R+   ++  A LP P+V      P  RP+P
Sbjct: 443 PTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQS--APLPWPQV-----LPTARPSP 495

Query: 174 PGTRCCPGARAAQLLREAAAAAQGLRAPAARLPEPTRRAP 213
            G              E    +QG    A + P P  + P
Sbjct: 496 HGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKLP 535



 Score = 35.4 bits (80), Expect = 0.076
 Identities = 63/249 (25%), Positives = 85/249 (34%), Gaps = 39/249 (15%)

Query: 31  PAKGKTICTRF--GDKRSSGQAGNKSERELQARTPA-----PPRERGESSSPRGPTLRGR 83
           P +  T  TR   G + + GQA      E Q R        PP  RG++ S   P  RG 
Sbjct: 34  PLEDNTPATRTTKGAREAGGQAQAMELPEAQPRQARDGELKPPSLRGQAPSST-PGKRGS 92

Query: 84  AKTTRGRSQGAGATETSAGNSAATAAPHPTPASYPQGTISPPQLPAPRPKRFGGKQRPLW 143
            +T  GRS         A +  A  A    P  Y  G  S       +P      + P  
Sbjct: 93  PQTPPGRSP------LQAPSRLAGRAEGSPPQRYILGIASS----RTKPTLDETPENP-- 140

Query: 144 RIRGWETTVARLPEPRVGK-LGKGPPPRPAPPGTRCCPGARAAQLLR------------E 190
                +   A+LPE    +  G G P RP  P T   P A      R             
Sbjct: 141 -----QLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAEELGFHRCFQEPPSSFTSTN 195

Query: 191 AAAAAQGLRAPAARLPEPTRRAPGRPGCLPTAAAAAADALWRSRRAPLPPTEFLSPRRTR 250
             + +   R PA   P+    +P +PG  P   A+ AD+   +     P   F  P    
Sbjct: 196 YTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQASGADSWPPAAENSFPGANFGVP-PAE 254

Query: 251 PRKHPERTR 259
           P   P+ +R
Sbjct: 255 PEPIPKGSR 263



 Score = 32.7 bits (73), Expect = 0.49
 Identities = 33/133 (24%), Positives = 54/133 (40%), Gaps = 25/133 (18%)

Query: 63   PAPPRERGESSSPRGPTLRGRAKTTRGRSQGAGAT-ETSAGNSAATAAPHPTPASYPQGT 121
            PA P+ +       GP+ +G      G   G G+  + ++G   +  A  P   S+P  +
Sbjct: 3693 PATPKAKP------GPSSQGSGSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRS 3746

Query: 122  ISPPQLPA-------PRPKRFGGKQRPLWRI----RGWETT---VARLPEP----RVGKL 163
             +P +LPA        +  R  G+Q P   +    +G  +T     ++P P     VG  
Sbjct: 3747 PAPERLPARAQAKSCTKGPREAGEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVGSF 3806

Query: 164  GKGPPPRPAPPGT 176
            G+ P     PP T
Sbjct: 3807 GRAPSAPDKPPRT 3819


>gi|148229134 ring finger and KH domain containing 2 [Homo sapiens]
          Length = 659

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 47/123 (38%), Positives = 52/123 (42%), Gaps = 21/123 (17%)

Query: 101 AGNSAATAAPHPTPASYPQGTISPPQLPAPRPKRFGGKQRPLWRIRGWETTVARLPEPRV 160
           +G+SAA A     PA  PQ    PP  P P P   GG +     + G       L   R+
Sbjct: 3   SGSSAALALA-AAPAPLPQPPPPPPPPPPPLPPPSGGPE-----LEG----DGLLLRERL 52

Query: 161 GKLGKGPPPRPAPPGTRCCPGARAAQLLREAAAAAQGLRAPAARLPEPTRRAPGRPGCLP 220
             LG   P  PA PG         A  LR  AAAAQG    AA L    R  PGRPG  P
Sbjct: 53  AALGLDDPS-PAEPG---------APALRAPAAAAQGQARRAAELSPEERAPPGRPGA-P 101

Query: 221 TAA 223
            AA
Sbjct: 102 EAA 104



 Score = 34.7 bits (78), Expect = 0.13
 Identities = 27/82 (32%), Positives = 33/82 (40%), Gaps = 5/82 (6%)

Query: 167 PPPRPAPPGTRCCPGARAAQLLREAAAAAQGLRAPAARLPEPTRRAPGRPGCLPTAAAAA 226
           PPP P PP     P +   +L  +     +  R  A  L +P+   PG P     AAAA 
Sbjct: 21  PPPPPPPPPPPLPPPSGGPELEGDGLLLRE--RLAALGLDDPSPAEPGAPALRAPAAAAQ 78

Query: 227 ADALWRSRRAPLPPTEFLSPRR 248
             A    R A L P E   P R
Sbjct: 79  GQA---RRAAELSPEERAPPGR 97


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 70/280 (25%), Positives = 105/280 (37%), Gaps = 45/280 (16%)

Query: 47  SGQAGNKSERELQARTPAP-PRERGESSSPRGPTLRGRA-KTTRGRSQGAGATETSAGNS 104
           +G+ G +  R   +R+ +P PR+R + +SPRG   R  +   TR R   + A       +
Sbjct: 514 NGEVGRR-RRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRT 572

Query: 105 AATAAPHPTPASYPQGTISPPQLPAPRPKRFGGK-QRPLWRIRGWETTVARLPEPRVGKL 163
                  PTP    +    PP+  +P P+R+    QR        +   A  P P   + 
Sbjct: 573 -------PTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRA 625

Query: 164 GKGPPPR-----PAPPGTRCCP---------------GARAAQLLREAAAAAQGLRAPAA 203
              PPP+       PP  R  P               G+  ++  REA +     R    
Sbjct: 626 SPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKR---- 681

Query: 204 RLPEPTRRAPGRPGCLPTAAAAAADALWRSRRAPLPPTEFLSPRRTRPRKHPERTRRPAQ 263
             P P  RAP      P     A+ +  R R++P P T  +  RR      P++ ++ A 
Sbjct: 682 HSPSPRPRAPQTSSSPPPVRRGASSSPQR-RQSPSPSTRPI--RRVSRTPEPKKIKKAAS 738

Query: 264 ------RLESGCRGHCSRGAPALAPPKLSPPFPCLAQSAS 297
                 R  S  R       PA   P  +PP P  +QS S
Sbjct: 739 PSPQSVRRVSSSRSVSGSPEPAAKKPP-APPSPVQSQSPS 777



 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 65/270 (24%), Positives = 96/270 (35%), Gaps = 29/270 (10%)

Query: 43  DKRSSGQAGNKSERELQARTPAPPRERGESSSPRGPTLRGRAKTTRGRSQGAGATETSAG 102
           DK    +   +S RE + R+ +P R +  S SPR  +   R +  R  S+          
Sbjct: 150 DKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSP-------- 201

Query: 103 NSAATAAPHPTPASYPQGTISPPQLPAPRPKRFGGKQRPLWRIRGWETTVARLPEPRVGK 162
               T +  P+PA  P+     P+LP P  K     + P  +     + + ++P+P    
Sbjct: 202 -RHRTKSRSPSPA--PEKKEKTPELPEPSVK----VKEPSVQEATSTSDILKVPKPEPIP 254

Query: 163 LGKGPPPRPAPPGTRCCPGARAAQLLREAAAAAQGLRAPAARLPEPTRRAPGR---PGCL 219
             K P P       +     R     R  + +    R+P+   P    R+  R   P   
Sbjct: 255 EPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRR 314

Query: 220 PTAAAAAADALWRSRRAPLPPTEFLSPRRTRPRKHPERTRRPAQRLESGCRGHCSRG--- 276
           P+           S R   PP     P R R  + P R RR +    SG     S     
Sbjct: 315 PSPRRRP------SPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSR 368

Query: 277 APALAPPK--LSPPFPCLAQSASRAAGARR 304
           +P   PPK   SPP      S S +   RR
Sbjct: 369 SPPKKPPKRTSSPPRKTRRLSPSASPPRRR 398



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 39/175 (22%), Positives = 58/175 (33%), Gaps = 22/175 (12%)

Query: 16  PSRKLGRYRSPTPLRPAKGKTICTRFGDKRSSGQAGNKSERELQARTPAPPRERGESSSP 75
           P R++     P        K        K   G + ++S RE  AR+P P +    S  P
Sbjct: 631 PKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTRE--ARSPQPNKRHSPSPRP 688

Query: 76  RG--------PTLRGRAKTTRGRSQGAGATETSAGNSAA--------TAAPHPTPASYPQ 119
           R         P  RG + + + R   + +T      S           A+P P       
Sbjct: 689 RAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVS 748

Query: 120 GTISPPQLPAPRPKRFGGKQRPLWRIRGWETTVARLPEPRVGKLGKGPPPRPAPP 174
            + S    P P  K+      P   ++    +    P   V K  K P P P+PP
Sbjct: 749 SSRSVSGSPEPAAKKPPAPPSP---VQSQSPSTNWSPAVPV-KKAKSPTPSPSPP 799


>gi|239749199 PREDICTED: hypothetical protein XP_002346952 [Homo
           sapiens]
          Length = 209

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 63/197 (31%), Positives = 83/197 (42%), Gaps = 36/197 (18%)

Query: 82  GRAKTTRGRS----QGAGATETSAGNSAATAAPHPTPASYPQGTISPPQLPAPRPKRFGG 137
           G  + TR R     +G  + E++AG   +  APHP   + P       + P PR +   G
Sbjct: 42  GTCRLTRSRKSRLERGTFSPESAAGTEVS-GAPHPDSRTRPAA-----RPPHPRTRSPPG 95

Query: 138 KQRPLWRIRGWETTVARLPEPRVGKLGKGPPPRPAPPGTR-CCPGARAAQLLREAAAAAQ 196
           +        G  TT + +P PR  +   G   RPA PG R  C  ARA+     A AA Q
Sbjct: 96  RS-------GSGTTFSAVP-PRPSQHQSGSRLRPAAPGPRPGCSSARAS----PAPAAPQ 143

Query: 197 GLRAPAARLPEPTRRAPGRPGCLPTAAAAAADALWR--SRRAPLPPTEFLSPRRTRPRKH 254
                AA    P R A G  G  P +    +D +    SR    PP   L+ RR R    
Sbjct: 144 -----AAARTAPGRAASGGSG--PGSRGQGSDQVGARPSRAGGQPPP--LTCRRCRAA-- 192

Query: 255 PERTRRPAQRLESGCRG 271
           P R+ RP +R    CRG
Sbjct: 193 PRRSARPFRRPGLPCRG 209


>gi|239756550 PREDICTED: hypothetical protein XP_002344932 [Homo
           sapiens]
          Length = 177

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 44/112 (39%), Positives = 50/112 (44%), Gaps = 16/112 (14%)

Query: 163 LGKGPPPRPA--PPG---TRCCPGARAAQLLREAAAAAQGLRAPAARLPEPT--RRAPGR 215
           LG GP PR    P G    R  PG RA  L      AA  L   A+  P P   RRAP R
Sbjct: 29  LGPGPSPRRGRLPSGGLRLRARPGRRALGLPSPLELAAPSLVPNASASPRPVSCRRAPPR 88

Query: 216 PGCLPTAAAAAADALWRSRRAPLPPTEF-LSPRRTRPRKHPERTRRPAQRLE 266
           P  +P AA       WR R  P P +    +P R RP   P R+  PA+R E
Sbjct: 89  P--VPGAAR------WRGRPEPRPGSPAGPAPTRARPLGAPGRSAPPARRRE 132


>gi|239749077 PREDICTED: hypothetical protein XP_002346898 [Homo
           sapiens]
          Length = 334

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 94/341 (27%), Positives = 122/341 (35%), Gaps = 82/341 (24%)

Query: 33  KGKTICTRFGDK-----RSSGQAGNKSERELQARTPAPP---RERGESSSPRGPTLRGRA 84
           K KT C R  D      R S Q G++     +A   AP    +E+G++S    PT   R 
Sbjct: 8   KNKTTCLRGSDTAGVTCRVSSQDGDRRGLGREAAPGAPAEGEKEKGKNSRRPRPTC-SRG 66

Query: 85  KTTRGR-SQGAGATETSAGNSAATAAPHPTPASYPQGTISPPQLPAPRPKRFGGKQRPLW 143
           +T RGR  +GA   E  AG  A    P P  A+  +  +                 R L 
Sbjct: 67  RTERGRVERGADHQERPAG--APAHRPVPAAAAILRAAV----------------HRVLR 108

Query: 144 RIRGWETTVARLPEPRVGKLGKGP----PPRPAPPGTRCCPGARAAQLLREAAAAAQGLR 199
            +R      A + +   G   +GP    PPR    G R   G  +A  L        GLR
Sbjct: 109 VLRA----AAAVRDAERGLRREGPRRHAPPRKQLRGRRGAAGLVSAGHLGREPPRGGGLR 164

Query: 200 APAARLPEPT--------RRAPGRPGCLPTAAAAAADALWRSRRAPLPPTEFLSPRRTRP 251
            PA  +P P         R  P    C  +   AA                 L     RP
Sbjct: 165 PPAL-VPVPLATPLLLEGRSEPSTRACAVSGGQAA-----------------LLGAHVRP 206

Query: 252 RKHPERTRRPAQRLE-----SGCRGHCSRGAPALAPPKLSPPFPCLAQSASRAAGARRAL 306
              P+R  R A R +     +G RG   +G  A A P+  P       +   A GARRAL
Sbjct: 207 A--PDRAARCAPRAKKAGANAGARG---QGRGAAAGPERPPHVQGRRPAPRGAVGARRAL 261

Query: 307 SASRGRRGLLGSGSLALPLPGCREPRQRLHGSDGAAGA-RC 346
             + G+ G          L   RE R+R      AAG  RC
Sbjct: 262 LGAVGKAG---------GLTRARETRRRGEEGVPAAGTPRC 293


>gi|239746104 PREDICTED: hypothetical protein XP_002344198 [Homo
           sapiens]
          Length = 398

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 83/300 (27%), Positives = 105/300 (35%), Gaps = 50/300 (16%)

Query: 29  LRPAKGKTICTRFG------DKRSSGQAGNKSERELQARTPAPPRERGESSSPRGPTLRG 82
           LR ++ +   TR G       +R+   A   S R      PA   +     +  G  LRG
Sbjct: 78  LRKSRARLPRTRQGREDAGVGRRNRDPAEPGSLRPTSLGFPARAGQGRVQGAAPGRKLRG 137

Query: 83  RAKTTRGRSQGAGATETSAGNSAATAAPHPTPASYP--QGTISPPQLPAPRPKRFGGKQR 140
             KT  GRS  +G   + AG+ AA AA H   A +    G   P +LP   P   G   R
Sbjct: 138 EPKTPPGRSGPSGGVRSGAGHRAA-AAEHQLGAGFSVRNGPGPPARLPPAPP---GPLLR 193

Query: 141 PLWRIRGWETTVARLP--EPRVGKLGKGPPPRP---------APPGTRCCPGARAAQLLR 189
           P    R +       P  EP   KL   PPP P          PP  R         L  
Sbjct: 194 PARPPRPYFPRPRTPPTCEPPSRKL---PPPLPLCRSRWVLAPPPPVRPRLRVLTPPLAL 250

Query: 190 EAAAAAQGLRAPAAR----------------LPEPTRRAPGRPGCLPTAAAAAADALWRS 233
             A   +G R P+ R                L   +RRA G         AA   A   +
Sbjct: 251 RCALPERGSRTPSTRSAVLSGRVAGLGTELTLTPSSRRAHGSHALSSERQAAPTRAFCSA 310

Query: 234 RRAPLPPTEFLSPRRTRPRKHPERTRRPAQRLESGCRGHCSRGAPALAPPKLSP-PFPCL 292
              P PP+    P    P+   +  R+P  RL    R   +RGAP    P   P P P L
Sbjct: 311 DPLPRPPS--FVPSLPSPQAQGQAVRQP--RL---LRAALARGAPRGRTPSPRPGPAPAL 363



 Score = 33.5 bits (75), Expect = 0.29
 Identities = 51/199 (25%), Positives = 63/199 (31%), Gaps = 27/199 (13%)

Query: 141 PLWRIRGWETTVARLPEPRVGK---LGKGPPPRPAPPGTRCCPGARAAQLLREAAAAAQG 197
           P+ R R      ARL    V     LG  PP R   P +R  PG  +      A      
Sbjct: 3   PVGRSRSENADTARLFGTAVYTFEVLGALPPDRSPTPRSRVSPGVTSL-----AVGPGNP 57

Query: 198 LRAPAARLPEPTRRAPGRPGC---------LPTAAAAAADA-LWRSRRAPLPPTEFLSPR 247
            R   + +P      PG PG          LP       DA + R  R P  P       
Sbjct: 58  TRCQRSGVPY---EGPGAPGGQQLRKSRARLPRTRQGREDAGVGRRNRDPAEPGSL---- 110

Query: 248 RTRPRKHPERTRRPAQRLESGCRGHCSRGAPALAPPKLSPPFPCLAQSASRAAGARRALS 307
             RP       R    R++    G   RG P   P +  P     + +  RAA A   L 
Sbjct: 111 --RPTSLGFPARAGQGRVQGAAPGRKLRGEPKTPPGRSGPSGGVRSGAGHRAAAAEHQLG 168

Query: 308 ASRGRRGLLGSGSLALPLP 326
           A    R   G  +   P P
Sbjct: 169 AGFSVRNGPGPPARLPPAP 187


>gi|239745514 PREDICTED: hypothetical protein XP_002343509 [Homo
           sapiens]
          Length = 177

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 44/112 (39%), Positives = 50/112 (44%), Gaps = 16/112 (14%)

Query: 163 LGKGPPPRPA--PPG---TRCCPGARAAQLLREAAAAAQGLRAPAARLPEPT--RRAPGR 215
           LG GP PR    P G    R  PG RA  L      AA  L   A+  P P   RRAP R
Sbjct: 29  LGPGPSPRRGRLPSGGLRLRARPGRRALGLPSPLELAAPSLVPNASASPRPVSCRRAPPR 88

Query: 216 PGCLPTAAAAAADALWRSRRAPLPPTEF-LSPRRTRPRKHPERTRRPAQRLE 266
           P  +P AA       WR R  P P +    +P R RP   P R+  PA+R E
Sbjct: 89  P--VPGAAR------WRGRPEPRPGSPAGPAPTRARPLGAPGRSAPPARRRE 132


>gi|239743103 PREDICTED: hypothetical protein XP_002342755 [Homo
           sapiens]
          Length = 329

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 94/341 (27%), Positives = 122/341 (35%), Gaps = 82/341 (24%)

Query: 33  KGKTICTRFGDK-----RSSGQAGNKSERELQARTPAPP---RERGESSSPRGPTLRGRA 84
           K KT C R  D      R S Q G++     +A   AP    +E+G++S    PT   R 
Sbjct: 3   KNKTTCLRGSDTAGVTCRVSSQDGDRRGLGREAAPGAPAEGEKEKGKNSRRPRPTC-SRG 61

Query: 85  KTTRGR-SQGAGATETSAGNSAATAAPHPTPASYPQGTISPPQLPAPRPKRFGGKQRPLW 143
           +T RGR  +GA   E  AG  A    P P  A+  +  +                 R L 
Sbjct: 62  RTERGRVERGADHQERPAG--APAHRPVPAAAAILRAAV----------------HRVLR 103

Query: 144 RIRGWETTVARLPEPRVGKLGKGP----PPRPAPPGTRCCPGARAAQLLREAAAAAQGLR 199
            +R      A + +   G   +GP    PPR    G R   G  +A  L        GLR
Sbjct: 104 VLRA----AAAVRDAERGLRREGPRRHAPPRKQLRGRRGAAGLVSAGHLGREPPRGGGLR 159

Query: 200 APAARLPEPT--------RRAPGRPGCLPTAAAAAADALWRSRRAPLPPTEFLSPRRTRP 251
            PA  +P P         R  P    C  +   AA                 L     RP
Sbjct: 160 PPAL-VPVPLATPLLLEGRSEPSTRACAVSGGQAA-----------------LLGAHVRP 201

Query: 252 RKHPERTRRPAQRLE-----SGCRGHCSRGAPALAPPKLSPPFPCLAQSASRAAGARRAL 306
              P+R  R A R +     +G RG   +G  A A P+  P       +   A GARRAL
Sbjct: 202 A--PDRAARCAPRAKKAGANAGARG---QGRGAAAGPERPPHVQGRRPAPRGAVGARRAL 256

Query: 307 SASRGRRGLLGSGSLALPLPGCREPRQRLHGSDGAAGA-RC 346
             + G+ G          L   RE R+R      AAG  RC
Sbjct: 257 LGAVGKAG---------GLTRARETRRRGEEGVPAAGTPRC 288


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.132    0.413 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,009,086
Number of Sequences: 37866
Number of extensions: 1298255
Number of successful extensions: 15047
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 154
Number of HSP's successfully gapped in prelim test: 1588
Number of HSP's that attempted gapping in prelim test: 9955
Number of HSP's gapped (non-prelim): 5229
length of query: 346
length of database: 18,247,518
effective HSP length: 103
effective length of query: 243
effective length of database: 14,347,320
effective search space: 3486398760
effective search space used: 3486398760
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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