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Search of human proteins with 110618248
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|110618248 mucin and cadherin-like isoform 1 [Homo sapiens]
(845 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|110618248 mucin and cadherin-like isoform 1 [Homo sapiens] 1731 0.0
gi|110618250 mucin and cadherin-like isoform 3 [Homo sapiens] 923 0.0
gi|163965366 nascent polypeptide-associated complex alpha subuni... 104 3e-22
gi|116284392 mucin 2 precursor [Homo sapiens] 95 2e-19
gi|20143482 melanoma antigen family E, 1 [Homo sapiens] 92 2e-18
gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens] 84 5e-16
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 84 7e-16
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H... 83 9e-16
gi|218505787 protocadherin 15 isoform CD2-1 precursor [Homo sapi... 80 6e-15
gi|115387123 protocadherin 15 isoform CD1-4 precursor [Homo sapi... 80 8e-15
gi|218505798 protocadherin 15 isoform CD1-10 precursor [Homo sap... 80 8e-15
gi|218505793 protocadherin 15 isoform CD3-2 precursor [Homo sapi... 80 8e-15
gi|218505791 protocadherin 15 isoform CD3-1 precursor [Homo sapi... 80 8e-15
gi|218505789 protocadherin 15 isoform CD2-2 precursor [Homo sapi... 80 8e-15
gi|218505785 protocadherin 15 isoform CD1-9 precursor [Homo sapi... 80 8e-15
gi|218505781 protocadherin 15 isoform CD1-7 precursor [Homo sapi... 80 8e-15
gi|218505779 protocadherin 15 isoform CD1-6 precursor [Homo sapi... 80 8e-15
gi|218505777 protocadherin 15 isoform CD1-2 precursor [Homo sapi... 80 8e-15
gi|218505775 protocadherin 15 isoform CD1-1 precursor [Homo sapi... 80 8e-15
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 80 1e-14
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 80 1e-14
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 80 1e-14
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 80 1e-14
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 77 5e-14
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 77 5e-14
gi|160707881 formin 2 [Homo sapiens] 77 9e-14
gi|222352122 hypothetical protein LOC284297 [Homo sapiens] 76 1e-13
gi|148886692 FAT tumor suppressor homolog 3 [Homo sapiens] 75 2e-13
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 74 7e-13
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 74 7e-13
>gi|110618248 mucin and cadherin-like isoform 1 [Homo sapiens]
Length = 845
Score = 1731 bits (4484), Expect = 0.0
Identities = 845/845 (100%), Positives = 845/845 (100%)
Query: 1 MGSWALLWPPLLFTGLLVRPPGTMAQAQYCSVNKDIFEVEENTNVTEPLVDIHVPEGQEV 60
MGSWALLWPPLLFTGLLVRPPGTMAQAQYCSVNKDIFEVEENTNVTEPLVDIHVPEGQEV
Sbjct: 1 MGSWALLWPPLLFTGLLVRPPGTMAQAQYCSVNKDIFEVEENTNVTEPLVDIHVPEGQEV 60
Query: 61 TLGALSTPFAFRIQGNQLFLNVTPDYEEKSLLEAQLLCQSGGTLVTQLRVFVSVLDVNDN 120
TLGALSTPFAFRIQGNQLFLNVTPDYEEKSLLEAQLLCQSGGTLVTQLRVFVSVLDVNDN
Sbjct: 61 TLGALSTPFAFRIQGNQLFLNVTPDYEEKSLLEAQLLCQSGGTLVTQLRVFVSVLDVNDN 120
Query: 121 APEFPFKTKEIRVEEDTKVNSTVIPETQLQAEDRDKDDILFYTLQEMTAGASDYFSLVSV 180
APEFPFKTKEIRVEEDTKVNSTVIPETQLQAEDRDKDDILFYTLQEMTAGASDYFSLVSV
Sbjct: 121 APEFPFKTKEIRVEEDTKVNSTVIPETQLQAEDRDKDDILFYTLQEMTAGASDYFSLVSV 180
Query: 181 NRPALRLDRPLDFYERPNMTFWLLVRDTPGENVEPSHTATATLVLNVVPADLRPPWFLPC 240
NRPALRLDRPLDFYERPNMTFWLLVRDTPGENVEPSHTATATLVLNVVPADLRPPWFLPC
Sbjct: 181 NRPALRLDRPLDFYERPNMTFWLLVRDTPGENVEPSHTATATLVLNVVPADLRPPWFLPC 240
Query: 241 TFSDGYVCIQAQYHGAVPTGHILPSPLVLRPGPIYAEDGDRGINQPIIYSIFRGNVNGTF 300
TFSDGYVCIQAQYHGAVPTGHILPSPLVLRPGPIYAEDGDRGINQPIIYSIFRGNVNGTF
Sbjct: 241 TFSDGYVCIQAQYHGAVPTGHILPSPLVLRPGPIYAEDGDRGINQPIIYSIFRGNVNGTF 300
Query: 301 IIHPDSGNLTVARSVPSPMTFLLLVKGQQADLARYSVTQVTVEAVAAAGSPPRFPQRLYR 360
IIHPDSGNLTVARSVPSPMTFLLLVKGQQADLARYSVTQVTVEAVAAAGSPPRFPQRLYR
Sbjct: 301 IIHPDSGNLTVARSVPSPMTFLLLVKGQQADLARYSVTQVTVEAVAAAGSPPRFPQRLYR 360
Query: 361 GTVARGAGAGVVVKDAAAPSQPLRIQAQDPEFSDLNSAITYRITNHSHFRMEGEVVLTTT 420
GTVARGAGAGVVVKDAAAPSQPLRIQAQDPEFSDLNSAITYRITNHSHFRMEGEVVLTTT
Sbjct: 361 GTVARGAGAGVVVKDAAAPSQPLRIQAQDPEFSDLNSAITYRITNHSHFRMEGEVVLTTT 420
Query: 421 TLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPSTDVPPSPEAGGTTGPWTSTTSE 480
TLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPSTDVPPSPEAGGTTGPWTSTTSE
Sbjct: 421 TLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPSTDVPPSPEAGGTTGPWTSTTSE 480
Query: 481 VPRPPEPSQGPSTTSSGGGTGPHPPSGTTLRPPTSSTPGGPPGAENSTSHQPATPGGDTA 540
VPRPPEPSQGPSTTSSGGGTGPHPPSGTTLRPPTSSTPGGPPGAENSTSHQPATPGGDTA
Sbjct: 481 VPRPPEPSQGPSTTSSGGGTGPHPPSGTTLRPPTSSTPGGPPGAENSTSHQPATPGGDTA 540
Query: 541 QTPKPGTSQPMPPGVGTSTSHQPATPSGGTAQTPEPGTSQPMPPSMGTSTSHQPATPGGG 600
QTPKPGTSQPMPPGVGTSTSHQPATPSGGTAQTPEPGTSQPMPPSMGTSTSHQPATPGGG
Sbjct: 541 QTPKPGTSQPMPPGVGTSTSHQPATPSGGTAQTPEPGTSQPMPPSMGTSTSHQPATPGGG 600
Query: 601 TAQTPEAGTSQPMPPGMGTSTSHQPTTPGGGTAQTPEPGTSQPMPLSKSTPSSGGGPSED 660
TAQTPEAGTSQPMPPGMGTSTSHQPTTPGGGTAQTPEPGTSQPMPLSKSTPSSGGGPSED
Sbjct: 601 TAQTPEAGTSQPMPPGMGTSTSHQPTTPGGGTAQTPEPGTSQPMPLSKSTPSSGGGPSED 660
Query: 661 KRFSVVDMAALGGVLGALLLLALLGLAVLVHKHYGPRLKCCSGKAPEPQPQGFDNQAFLP 720
KRFSVVDMAALGGVLGALLLLALLGLAVLVHKHYGPRLKCCSGKAPEPQPQGFDNQAFLP
Sbjct: 661 KRFSVVDMAALGGVLGALLLLALLGLAVLVHKHYGPRLKCCSGKAPEPQPQGFDNQAFLP 720
Query: 721 DHKANWAPVPSPTHDPKPAEAPMPAEPAPPGPASPGGAPEPPAAARAGGSPTAVRSILTK 780
DHKANWAPVPSPTHDPKPAEAPMPAEPAPPGPASPGGAPEPPAAARAGGSPTAVRSILTK
Sbjct: 721 DHKANWAPVPSPTHDPKPAEAPMPAEPAPPGPASPGGAPEPPAAARAGGSPTAVRSILTK 780
Query: 781 ERRPEGGYKAVWFGEDIGTEADVVVLNAPTLDVDGASDSGSGDEGEGAGRGGGPYDAPGG 840
ERRPEGGYKAVWFGEDIGTEADVVVLNAPTLDVDGASDSGSGDEGEGAGRGGGPYDAPGG
Sbjct: 781 ERRPEGGYKAVWFGEDIGTEADVVVLNAPTLDVDGASDSGSGDEGEGAGRGGGPYDAPGG 840
Query: 841 DDSYI 845
DDSYI
Sbjct: 841 DDSYI 845
>gi|110618250 mucin and cadherin-like isoform 3 [Homo sapiens]
Length = 651
Score = 923 bits (2385), Expect = 0.0
Identities = 490/613 (79%), Positives = 505/613 (82%), Gaps = 34/613 (5%)
Query: 1 MGSWALLWPPLLFTGLLVRPPGTMAQAQYCSVNKDIFEVEENTNVTEPLVDIHVPEGQEV 60
MGSWALLWPPLLFTGLLVRPPGTMAQAQYCSVNKDIFEVEENTNVTEPLVDIHVPEGQEV
Sbjct: 1 MGSWALLWPPLLFTGLLVRPPGTMAQAQYCSVNKDIFEVEENTNVTEPLVDIHVPEGQEV 60
Query: 61 TLGALSTPFAFRIQGNQLFLNVTPDYEEKSLLEAQLLCQSGGTLVTQLRVFVSVLDVNDN 120
TLGALSTPFAFRIQGNQLFLNVTPDYEEKSLLEAQLLCQSGGTLVTQLRVFVSVLDVNDN
Sbjct: 61 TLGALSTPFAFRIQGNQLFLNVTPDYEEKSLLEAQLLCQSGGTLVTQLRVFVSVLDVNDN 120
Query: 121 APEFPFKTKEIRVEEDTKVNSTVIPETQLQAEDRDKDDILFYTLQEMTAGASDYFSLVSV 180
APEFPFKTKEIRVEEDTKVNSTVIPETQLQAEDRDKDDILFYTLQEMTAGASDYFSLVSV
Sbjct: 121 APEFPFKTKEIRVEEDTKVNSTVIPETQLQAEDRDKDDILFYTLQEMTAGASDYFSLVSV 180
Query: 181 NRPALRLDRPLDFYERPNMTFWLLVRDTPGENVEPSHTATATLVLNVVPADLRPPWFLPC 240
NRPALRLDRPLDFYERPNMTFWLLVRDTPGENVEPSHTATATLVLNVVPADLRPPWFLPC
Sbjct: 181 NRPALRLDRPLDFYERPNMTFWLLVRDTPGENVEPSHTATATLVLNVVPADLRPPWFLPC 240
Query: 241 TFSDGYVCIQAQYHGAVPTGHILPSPLVLRPGPIYAEDGDRGINQPIIYSIFRGNVNGTF 300
TFSDGYVCIQAQYHGAVPTGHILPSPLVLRPGPIYAEDGDRGINQPIIYSIFRGNVNGTF
Sbjct: 241 TFSDGYVCIQAQYHGAVPTGHILPSPLVLRPGPIYAEDGDRGINQPIIYSIFRGNVNGTF 300
Query: 301 IIHPDSGNLTVARSVPSPMTFLLLVKGQQADLARYSVTQVTVEAVAAAGSPPRFPQRLYR 360
IIHPDSGNLTVARSVPSPMTFLLLVKGQQADLARYSVTQVTVEAVAAAGSPPRFPQRLYR
Sbjct: 301 IIHPDSGNLTVARSVPSPMTFLLLVKGQQADLARYSVTQVTVEAVAAAGSPPRFPQRLYR 360
Query: 361 GTVARGAGAGVVVKDAAAPSQPLRIQAQDPEFSDLNSAITYRITNHSHFRMEGEVVLTTT 420
GTVARGAGAGVVVKDAAAPSQPLRIQAQDPEFSDLNSAITYRITNHSHFRMEGEVVLTTT
Sbjct: 361 GTVARGAGAGVVVKDAAAPSQPLRIQAQDPEFSDLNSAITYRITNHSHFRMEGEVVLTTT 420
Query: 421 TLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPSTDVPPSPE----------AGGT 470
TLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPST PS + GG
Sbjct: 421 TLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPSTGGGPSEDKRFSVVDMAALGGV 480
Query: 471 TGP-WTSTTSEVPRPPEPSQGPSTTSSGGGTGPHPPSG---TTLRPPTSSTPGGPPGAEN 526
G + GP G P G P + P
Sbjct: 481 LGALLLLALLGLAVLVHKHYGPRLKCCSGKAPEPQPQGFDNQAFLPDHKANWAPVP---- 536
Query: 527 STSHQPATPGGDTAQTPKPGTSQPMPPGVGTSTSHQPATPSGGTAQTPEPGTSQPMPPSM 586
S +H P A+ P P ++P PPG PA+P GG + P + P ++
Sbjct: 537 SPTHDP-----KPAEAPMP--AEPAPPG--------PASP-GGAPEPPAAARAGGSPTAV 580
Query: 587 GTSTSHQPATPGG 599
+ + + GG
Sbjct: 581 RSILTKERRPEGG 593
Score = 408 bits (1048), Expect = e-113
Identities = 194/195 (99%), Positives = 195/195 (100%)
Query: 651 PSSGGGPSEDKRFSVVDMAALGGVLGALLLLALLGLAVLVHKHYGPRLKCCSGKAPEPQP 710
PS+GGGPSEDKRFSVVDMAALGGVLGALLLLALLGLAVLVHKHYGPRLKCCSGKAPEPQP
Sbjct: 457 PSTGGGPSEDKRFSVVDMAALGGVLGALLLLALLGLAVLVHKHYGPRLKCCSGKAPEPQP 516
Query: 711 QGFDNQAFLPDHKANWAPVPSPTHDPKPAEAPMPAEPAPPGPASPGGAPEPPAAARAGGS 770
QGFDNQAFLPDHKANWAPVPSPTHDPKPAEAPMPAEPAPPGPASPGGAPEPPAAARAGGS
Sbjct: 517 QGFDNQAFLPDHKANWAPVPSPTHDPKPAEAPMPAEPAPPGPASPGGAPEPPAAARAGGS 576
Query: 771 PTAVRSILTKERRPEGGYKAVWFGEDIGTEADVVVLNAPTLDVDGASDSGSGDEGEGAGR 830
PTAVRSILTKERRPEGGYKAVWFGEDIGTEADVVVLNAPTLDVDGASDSGSGDEGEGAGR
Sbjct: 577 PTAVRSILTKERRPEGGYKAVWFGEDIGTEADVVVLNAPTLDVDGASDSGSGDEGEGAGR 636
Query: 831 GGGPYDAPGGDDSYI 845
GGGPYDAPGGDDSYI
Sbjct: 637 GGGPYDAPGGDDSYI 651
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 104 bits (260), Expect = 3e-22
Identities = 99/344 (28%), Positives = 129/344 (37%), Gaps = 58/344 (16%)
Query: 457 PSTDVPPSPEAG--GTTGPWTSTTSEVPRPPEPSQGPSTTSSGGGTGPHPPSGTTLRP-- 512
P PPSP+ T P + T+ P P GP+T S G P PP+ T P
Sbjct: 1035 PPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKG--APTPPAATPPSPKG 1092
Query: 513 ------------PTSSTPGGPPGAENSTSHQ--PATPGGDTAQTPKPGTSQPMPPGVGTS 558
P ++TP P G + H+ P TP T +PK G + P P G T+
Sbjct: 1093 GPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAA-TPPSPKGGLATPPPKGAPTT 1151
Query: 559 TSHQPATPSGGTAQTP---EPGTSQPMPPS----MGTSTSHQPATPGGGTAQTPEAGTSQ 611
+ P +P GG A P P T PPS + T + T T +P+ G +
Sbjct: 1152 PAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLAT 1211
Query: 612 PMPPGMGTSTSHQPTTPGGGTAQTPEPGTSQPMPLSKSTPSSGGGPSEDKRFSVVDMAAL 671
P P G T+ + P +P GG A TP P + P + + PS GGP+ A
Sbjct: 1212 PSPKGAPTTPAATPPSPKGGLA-TPSPKGAPTTP-AATPPSPKGGPATPPPKGAPTPPAA 1269
Query: 672 GGVLGALLLLALLGLAVLVHKHYGPRLKCCSGKAPEPQPQGFDNQAFLPDHKANWAPVPS 731
P LK G P +G N A + P S
Sbjct: 1270 ----------------------TPPSLK---GGLATPPHKGAPNPAVVTPPSPKGGPATS 1304
Query: 732 PTHD-PKPAEAPMPAEPAPPGPASPGGAPEPPAAARAG--GSPT 772
P P P A P+ PG P GAP PPA G+PT
Sbjct: 1305 PPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPT 1348
Score = 102 bits (253), Expect = 2e-21
Identities = 97/341 (28%), Positives = 123/341 (36%), Gaps = 46/341 (13%)
Query: 457 PSTDVPPSPEAG-GTTGPWTSTTSEVPRPPEPSQGPSTTSSGGGTGPHPPSGTTLRPPTS 515
P PPSP+ G T P + T PP P GP+T S G P PP+ T P
Sbjct: 942 PPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGA--PTPPAATPPSPKGG 999
Query: 516 STPGGPPGAENSTSHQPATPGGDTAQTPKPGTSQPMPPGVGTSTSHQPATPSGGTAQTPE 575
P GA + P +P G A TP P G T + P +P G A TP
Sbjct: 1000 PATPSPKGAPTPPAVTPPSPKGSPAATP-------FPKGASTPPAATPPSPKGSPAATPL 1052
Query: 576 PGTSQPMPPSMGTSTSHQPATPG--------GGTAQTPEAGTSQPMPPGMGTSTSHQPTT 627
P + P + S PATP T +P+ G + P P G + P +
Sbjct: 1053 PKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPS 1112
Query: 628 PGGGTAQTPE------PGTSQPMPL-SKSTPSSGGGPSEDKRFSVVDMAALGGVL----- 675
P GG A P P + P P +TP G P+ + + GG+
Sbjct: 1113 PKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTP---AATPPSPKGGLATPPPK 1169
Query: 676 GALLLLALL------GLAVLVHKHYGPRLKCCSGKAPE-----PQPQGF-DNQAFLPDHK 723
GA A GLA K P + +P+ P P+G A P
Sbjct: 1170 GAPTTPAATPPSPKGGLATPSPKG-APTTPAATPPSPKGGLATPSPKGAPTTPAATPPSP 1228
Query: 724 ANWAPVPSPTHDPKPAEAPMPAEPAPPGPASPGGAPEPPAA 764
PSP P A P+ P P GAP PPAA
Sbjct: 1229 KGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAA 1269
Score = 92.4 bits (228), Expect = 2e-18
Identities = 101/353 (28%), Positives = 128/353 (36%), Gaps = 80/353 (22%)
Query: 462 PPSPEAGG--TTGPWTSTTSEVPRPPEPSQGPSTTSSGGGTGPHPPSGTTLRPPTSSTPG 519
PPSP+ GG T P + T+ PP P G +T S G P P+ T P
Sbjct: 1156 PPSPK-GGLATPPPKGAPTTPAATPPSPKGGLATPSPKG--APTTPAATPPSPKGGLATP 1212
Query: 520 GPPGAENSTSHQPATPGGDTAQTPKPGTSQPMPPGVGTSTSHQPATPSGGTAQTPEPGTS 579
P GA P TP T +PK G + P P G T+ + P +P GG A P G
Sbjct: 1213 SPKGA-------PTTPAA-TPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAP 1264
Query: 580 QP---MPPSM--GTSTSHQ----------PATPGGGTAQTPEAGTSQPMPPGMGTSTSHQ 624
P PPS+ G +T P +P GG A +P G P P S
Sbjct: 1265 TPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTP-PAATPPSPKGS 1323
Query: 625 PTTPGGGTAQTPEPGTSQPMP-----LSKSTPSSGGGPSEDKRFSVVDMAALGGVLGALL 679
P TP A TP P + P P L +TPSS GGP+
Sbjct: 1324 PGTPPPKGAPTP-PAVTPPSPKGTPTLPATTPSSKGGPTTPS------------------ 1364
Query: 680 LLALLGLAVLVHKHYGPRLKCCSGKAPEPQPQGFDNQAFLPDHKANWAPVPSPTHDP-KP 738
GP P P A P +PSP DP P
Sbjct: 1365 ------------SKEGP-------TPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSP 1405
Query: 739 AEAPMPAEPAPPGPASPGGAPEPPAAARAGGSPTAVRSILTKE----RRPEGG 787
A P+ + AP P + GA P ++ +P AV + K+ P+GG
Sbjct: 1406 AVIPLSPKKAPATPVTREGAATP---SKGDLTPPAVTPVSLKKAPATSAPKGG 1455
Score = 84.3 bits (207), Expect = 4e-16
Identities = 103/362 (28%), Positives = 127/362 (35%), Gaps = 72/362 (19%)
Query: 456 PPSTDVPPSPEA-------GGTTGPWTSTTSEVPRPPEPSQGPST-------------TS 495
PPS P+P A G T P + T V P P +GP+T +S
Sbjct: 858 PPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSS 917
Query: 496 SGGGTGPHPPSGTTLRPPTSSTPGGPPGAENSTSHQPATPGGDTAQT--------PKPGT 547
P G P P P S PATP A T PK G
Sbjct: 918 PKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGP 977
Query: 548 SQPMPPGVGTSTSHQPATPSGGTAQTPEPGTSQPMPPSM--GTSTSHQPATPGGGTAQTP 605
+ P P G T + P +P GG A TP P P PP++ + ATP A TP
Sbjct: 978 ATPSPKGAPTPPAATPPSPKGGPA-TPSP-KGAPTPPAVTPPSPKGSPAATPFPKGASTP 1035
Query: 606 EAGT---------SQPMPPGMGTSTSHQPTTPGGGTAQTPEPGTSQPMPLSKSTPSSGGG 656
A T + P+P G T+ + +P GG A G P P + + PS GG
Sbjct: 1036 PAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGA--PTPPAATPPSPKGG 1093
Query: 657 PS--EDKRFSVVDMAALGGVLGALLLLALLGLAVLVHKHYGPRLKCCSGKAPE-----PQ 709
P+ K + A G GLA HK P + +P+ P
Sbjct: 1094 PATPSPKGAPMPPAATPPSPKG--------GLATPPHKG-APTTPAATPPSPKGGLATPP 1144
Query: 710 PQGFDNQAFLPDHKANWAPVP-SPTHDPKPAEAPMPAEPAPPGP------ASPGGAPEPP 762
P+G P A P P P P AP PP P SP GAP P
Sbjct: 1145 PKG------APTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1198
Query: 763 AA 764
AA
Sbjct: 1199 AA 1200
Score = 83.6 bits (205), Expect = 7e-16
Identities = 104/375 (27%), Positives = 135/375 (36%), Gaps = 54/375 (14%)
Query: 457 PSTDVPPSPEAG-GTTGPWTSTTSEVPRPPEPSQGPSTTSSGGG------TGPHPPSGTT 509
P+ PPSP+ G T+ P + T PP P P T G T P P T
Sbjct: 1289 PAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPT 1348
Query: 510 LRPPTSSTPGGP--PGAENSTSHQPATP---GGD--TAQTPKPGTSQPMPPGVGTSTS-- 560
L T S+ GGP P ++ + ATP GG T +PK G + P P G TS +
Sbjct: 1349 LPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVI 1408
Query: 561 -----HQPATP-SGGTAQTPEPGTSQPMPPSMGTSTSHQPAT--PGGGTAQTPEAGTSQP 612
PATP + A TP G P P S PAT P GG A TP +
Sbjct: 1409 PLSPKKAPATPVTREGAATPSKGDLTP-PAVTPVSLKKAPATSAPKGGPA-TPSSKGDPT 1466
Query: 613 MPPGMGTSTSHQPTTPGGGTAQTPEPGTSQPMPLSKSTPSSGGGPSEDKRFSVVDMAALG 672
+P S P T+ +P+ + P P+ T PS K +
Sbjct: 1467 LPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPT-LPAVIPSSPKEVPATPSSRRD 1525
Query: 673 GVLGALLLLALLGLAVLVHKH--YGPRLKCCSGKAPEPQPQGFDNQAFLPDHKANWAP-- 728
+ LL+ A L K P + S K P + A +A+ P
Sbjct: 1526 PIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAV 1585
Query: 729 ---------------VPSPTHDPKPAEAPMPAEPAPP----GPASPG--GAPEPPAAARA 767
+P P P EAP P PP GPA+P G P P +
Sbjct: 1586 TPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPS 1645
Query: 768 G--GSPTAVRSILTK 780
SPT+ S+ K
Sbjct: 1646 SLKDSPTSPASVTCK 1660
Score = 72.4 bits (176), Expect = 2e-12
Identities = 101/409 (24%), Positives = 127/409 (31%), Gaps = 100/409 (24%)
Query: 414 EVVLTTTTLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPSTDVPPSPEAGGT--- 470
E LTT L + V T T++ + PS +PP+ GT
Sbjct: 692 EGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKV 751
Query: 471 -----TGPWTSTTSEVPRPPEPSQGPSTTSSGGGT------GPHP----PSGTTLRPPTS 515
T S P G S T+S GT P P S T RPPT
Sbjct: 752 DGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTK 811
Query: 516 STPGGPPGA-----------------ENSTSHQPATPGGDTAQTPKPGTSQPMPPGVGTS 558
GP ENS S Q + T +P P P P G T
Sbjct: 812 KGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTP----PSPKGAPTP 867
Query: 559 TSHQPATPSGGTA---QTPEPGTSQPMPPSMGTSTSHQPATPG-GGTAQTPEAGTSQPMP 614
++ P +P G T +TP P P G +T P T+ +P+ + P P
Sbjct: 868 SAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAP 927
Query: 615 PGMGTSTSHQPT-TPGGGTAQTPEPGTSQPMPLSKSTPSSGGGPSEDKRFSVVDMAALGG 673
G+ S S + TP T +P+ G + P P TP + PS
Sbjct: 928 KGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSP-------------- 973
Query: 674 VLGALLLLALLGLAVLVHKHYGPRLKCCSGKAPEPQPQGFDNQAFLPDHKANWAPVPSPT 733
G P P+G A P +P P
Sbjct: 974 ----------------------------KGGPATPSPKG----APTPPAATPPSPKGGPA 1001
Query: 734 HDPKPAEAPMPAEPAPPGPAS-------PGGAPEPPAAARAG--GSPTA 773
P P AP P PP P P GA PPAA GSP A
Sbjct: 1002 -TPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAA 1049
Score = 69.3 bits (168), Expect = 1e-11
Identities = 91/378 (24%), Positives = 130/378 (34%), Gaps = 32/378 (8%)
Query: 412 EGEVVLTTTTLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPSTDVPPSPEAGGTT 471
+G TTT + ++ V GT TT+ + + + P V PSP+ T
Sbjct: 664 KGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCP---VAPSPQ--NTC 718
Query: 472 GPWTSTTSEVPRPPEPSQGPSTTSSGGGTGPHPPSG---TTLRPPTSSTPGGPPGAENST 528
P +T P P+ PS +G G G T+ P +S+P P ++
Sbjct: 719 AP-LATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGA 777
Query: 529 SHQPATPGGDTAQTPKPGTSQPMPPGVGTSTSHQPATPSGGTAQTPEPGTSQPMPPSMGT 588
S ++ G T P P+ V T P TP S P+ P +
Sbjct: 778 SATASSKGTLTYLADSP---SPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEAS 834
Query: 589 -----STSHQPATPGGGTAQTPEAGTSQPMPPGMGTSTSHQPTTPGGGTAQTPEPGTSQP 643
S S Q + T +P + P P G T ++ P +P G T P T P
Sbjct: 835 FLPENSLSFQGSKDSPATTHSP----TPPSPKGAPTPSAVTPLSPKGVT--LPPKETPTP 888
Query: 644 MPLSKSTPSSGGGPSEDKRFSVVDMAALGGVLGALLLLALLGLAVLVHKHYGPRLKCCSG 703
++ P G K+ + M + A A G+ P +
Sbjct: 889 SVVNLPFPKEGPATPAPKQAPALSMTS-SSPKKARATPAPKGIPASPSPKGAPTPPAATP 947
Query: 704 KAPE-----PQPQGFDN-QAFLPDHKANWAPVPSPTHDPKPAEAPMPAEPAPPGPASPGG 757
+P+ P P+ A P PSP P P A P+ P SP G
Sbjct: 948 PSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKG 1007
Query: 758 APEPPAAARAG--GSPTA 773
AP PPA GSP A
Sbjct: 1008 APTPPAVTPPSPKGSPAA 1025
Score = 68.6 bits (166), Expect = 2e-11
Identities = 88/339 (25%), Positives = 118/339 (34%), Gaps = 68/339 (20%)
Query: 462 PPSPEAGGTTGPWTSTTSEVPRPPEPSQGPSTTSSGGGTGPHPPSGTTLRPPTSSTPGGP 521
PPSP+ G GP T P PP + P + G T PH
Sbjct: 1248 PPSPK-G---GPATPPPKGAPTPPAAT--PPSLKGGLATPPH------------------ 1283
Query: 522 PGAENSTSHQPATPGGDTAQTPKPGTSQPMPPGVGTSTSHQPATPSGGTAQTPEPGTSQP 581
GA N P +P G A +P G P P S P TP A TP P + P
Sbjct: 1284 KGAPNPAVVTPPSPKGGPATSPPKGAPTP-PAATPPSPKGSPGTPPPKGAPTP-PAVTPP 1341
Query: 582 MPPSMGTSTSHQPATPGGGTAQTPEAGTSQPMPPGMGTSTSHQPTTPGGGTAQTPEPGTS 641
P T + P++ GG T + + G P PP + P+ GG P P
Sbjct: 1342 SPKGTPTLPATTPSSKGGPTTPSSKEG---PTPP------AATPSHKGGPAMTPPSPKRG 1392
Query: 642 QPMPLSKSTPSSGG----GPSEDKRFSVVDMAALGGVLGALLLLALLGLAVLVHKHYGPR 697
+P K P+S P + V A G L A+ +++ P
Sbjct: 1393 PAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSL----KKAPA 1448
Query: 698 LKCCSGKAPEPQPQGFDNQAFLPDHKANWAPVPSPTHDPKPAEA-------PMPAEPAPP 750
G P +G D PSP P P + PA PAP
Sbjct: 1449 TSAPKGGPATPSSKG--------DPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPM 1500
Query: 751 G--------PASPGGAPEPPAAARAGGSPTAVRSILTKE 781
G P+SP P P++ R +PTA ++L+K+
Sbjct: 1501 GAPTLPAVIPSSPKEVPATPSSRRDPIAPTA--TLLSKK 1537
Score = 63.9 bits (154), Expect = 6e-10
Identities = 100/389 (25%), Positives = 137/389 (35%), Gaps = 86/389 (22%)
Query: 456 PPSTDVPPSPE----------AGGTTGPWTSTTSEVPRPPEPSQGPSTTSSGGGTGPHPP 505
PPS PP+P+ A T P + T P P + P+T SS P P
Sbjct: 1472 PPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSR--RDPIAP 1529
Query: 506 SGTTLRPPTSSTPGGPPGAENSTSHQPATPGGDTAQTPKPGTSQPMPPGVGTSTSHQPAT 565
+ T L T +T + P T +PK + P P PAT
Sbjct: 1530 TATLLSKKTPAT---------LAPKEALIPPAMTVPSPKKTPAIPTP-------KEAPAT 1573
Query: 566 PSGGTAQTPEP-------GTSQP----MPPSMGTSTSHQPATPGGGTAQTPEAGTSQPMP 614
PS A +P G P +PP++ + + + TP T +PE G + P P
Sbjct: 1574 PSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAP 1633
Query: 615 PGMGT-------STSHQPTTPGGGT----AQTPEPGTSQP-------------MPLSKST 650
G T S PT+P T A P+ P P +ST
Sbjct: 1634 KGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPEST 1693
Query: 651 P----SSGGGPSEDKRFSV-----VDMAALGGVLGALLLLALLGLAVLVHKHYGPRLKCC 701
P + GP K + D +A G G L +A L + V K K
Sbjct: 1694 PIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPL-LPVQKDSS---KTA 1749
Query: 702 SGKAPEPQPQGFDNQAFLPDHKANWAPVPSPTHD---PKPAEAPMPAEPAPPG--PASPG 756
GK P+G P+ KA+ P+ + + PKP A + A P+PP P +P
Sbjct: 1750 KGKDASHSPKG---PLAPPESKAS-TPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPS 1805
Query: 757 GAPE-PPAAARAGGSPTAVRSILTKERRP 784
P PP SP V +K P
Sbjct: 1806 PVPTLPPKQQFLPSSPGLVLESPSKPLAP 1834
Score = 61.2 bits (147), Expect = 4e-09
Identities = 90/391 (23%), Positives = 132/391 (33%), Gaps = 87/391 (22%)
Query: 441 GTATTVIEIQVSEQEPPSTDVP----PSPEAGGTTGPWTSTTS--EVPRPPEPSQGPSTT 494
G T+ I +S ++ P+T V +P G T P + S + P P GP+T
Sbjct: 1400 GDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATP 1459
Query: 495 SSGGGTGPHPPSGTTLRPPTSSTPGGPPGAENSTSHQPATPGGDTAQTPKPGTSQPMPPG 554
SS G P+ + PP+ P P S+S PK + P P G
Sbjct: 1460 SSKGD-----PTLPAVTPPSPKEPPAPKQVATSSS-------------PKKAPATPAPMG 1501
Query: 555 VGT----------------STSHQPATPSGGTAQTPEPGTSQP----MPPSMGT------ 588
T S+ P P+ P T P +PP+M
Sbjct: 1502 APTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKT 1561
Query: 589 ----STSHQPATPGGGTAQTPEA-------GTSQP----MPPGMGTSTSHQPTTPGGGTA 633
+ PATP A +P A G P +PP + + + + TP T
Sbjct: 1562 PAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTP 1621
Query: 634 QTPEPGTSQPMPLSKSTPSSGGGPSEDKRFSVVDMAALGGVLGALLLLALLGL------- 686
+PE G + P P K TP+S + S A++ +GA + A GL
Sbjct: 1622 PSPEKGPATPAP--KGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPT 1679
Query: 687 -----AVLVHKHYGPRLKCCSGKAPEPQPQGFDNQAFLPDHKA-NWAPVPSPTHDPKP-- 738
V P + + K P+ + + PD A N + P T P P
Sbjct: 1680 ALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLL 1739
Query: 739 -----AEAPMPAEPAPPGPASPGGAPEPPAA 764
+ + A P P PE A+
Sbjct: 1740 PVQKDSSKTAKGKDASHSPKGPLAPPESKAS 1770
Score = 37.7 bits (86), Expect = 0.045
Identities = 89/397 (22%), Positives = 128/397 (32%), Gaps = 82/397 (20%)
Query: 440 SGTATTVIEIQVSEQEPPSTDVPPSPEAGGTTGPWTSTTSEVPRPPEPSQGPSTTSSGGG 499
S T + I VS P D+ P + P VP E + P + + G
Sbjct: 494 STQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGA--PFSPAQAGL 551
Query: 500 TGPHPPSGTTLRPPTSSTPGGPPGAENSTSHQPATPGGDTAQTPKPGTSQPMPPGVGTST 559
T P T+ P + P P + STS P P A K +P+P G S+
Sbjct: 552 TTKKDP---TVLPLVQAAPKNSPSFQ-STSSSPEIPLSPEATLAKKSLGEPLPIGKPASS 607
Query: 560 SHQP--ATPSGGTAQTPE---PGTSQPMPPS-------------------------MGTS 589
P S +T P ++ P+ S GTS
Sbjct: 608 MTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTS 667
Query: 590 TSHQPATP--GGGTAQTP-----EAGTSQPMPPGMGTSTSHQPTTPGGGTAQTP------ 636
T A+P G + P + GT +P + T++ + P P P
Sbjct: 668 TYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPL-VPTASENCPVAPSPQNTCAPLATLVL 726
Query: 637 EPGTSQPMPLSKSTPSSGGGPSEDKRFSVVDMAALGGVL--------------------G 676
P + +P S S P +G P K + +AL V G
Sbjct: 727 APEIPKSVP-SPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKG 785
Query: 677 ALLLLA----LLGLAVLVHKHYGPRLKCCSGKAPE----PQPQGFDNQAFLPDHKANW-- 726
L LA LG++V P K +G P +FLP++ ++
Sbjct: 786 TLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQG 845
Query: 727 -APVPSPTHDPKPAEAPMPAEPAPPGPASPGGAPEPP 762
P+ TH P P P+ P SP G PP
Sbjct: 846 SKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPP 882
Score = 34.7 bits (78), Expect = 0.38
Identities = 53/205 (25%), Positives = 72/205 (35%), Gaps = 17/205 (8%)
Query: 468 GGTTGPWTSTTSEVPRPPEPSQGPSTTSSGGGTGPHPPSGTTLRPPTSSTPGG-PPGAEN 526
G T +T E+P+P + +S+ T G TL PP S P P A N
Sbjct: 3 GEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAAN 62
Query: 527 STS--HQPATPGGDTAQTPKPGTSQPMPPGVGTSTSHQPATPS--GGTAQTPEPGTSQPM 582
S P+T + P P +S +GT+ P+ G + PM
Sbjct: 63 QASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPM 122
Query: 583 --PPSMGTSTSHQPATPGGGTAQTPEA-GTSQPMPPGMGTSTSHQPTTPGGG--TAQTP- 636
P GT +S P A P + S PP + TS G T P
Sbjct: 123 IAPTLKGTPSSSAPLAL---VALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPI 179
Query: 637 ---EPGTSQPMPLSKSTPSSGGGPS 658
EP T+ S+ P+ G PS
Sbjct: 180 APSEPKTNLNKVPSEVVPNPKGTPS 204
Score = 32.3 bits (72), Expect = 1.9
Identities = 35/154 (22%), Positives = 50/154 (32%), Gaps = 5/154 (3%)
Query: 462 PPSPEAGGTTGPWTSTTSEVPRPPEPSQGPSTTSSGGGTGPHPPSGTTLRPPTSSTPGGP 521
P +P + P T+ E P S S S + P PS PP
Sbjct: 1761 PLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSS 1820
Query: 522 PGAENSTSHQPATPGGDTAQTPKPGTSQPMPPGVG-TSTSHQPATPSGGTAQTPEPGTSQ 580
PG + +P P + P +P+ GV S TP P P Q
Sbjct: 1821 PGLVLESPSKPLAPADEDELLPLI-PPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQ 1879
Query: 581 PMPPS---MGTSTSHQPATPGGGTAQTPEAGTSQ 611
P+ + GT + + P + +A T Q
Sbjct: 1880 PVTKNNKGSGTESDSDESVPELEEQDSTQATTQQ 1913
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 95.1 bits (235), Expect = 2e-19
Identities = 80/266 (30%), Positives = 106/266 (39%), Gaps = 34/266 (12%)
Query: 419 TTTLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPSTDVPPSPEAGGTTGPWTSTT 478
TTT + + T + T TT + PP T P + P ++TT
Sbjct: 1403 TTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTT 1462
Query: 479 SEVPRPPEPSQGPSTTSSGGGTGPHPPSGTTLRPPTSSTPGGP------PGAENSTSHQP 532
+ P P P+TT S T P PP+ TT PP ++TP P P A +T
Sbjct: 1463 T--PPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPT 1520
Query: 533 ATPGGDT--------AQTPKPGTSQPMPPGVGTSTSHQPATPS--GGTAQTP-------E 575
TP T TP P T+ P+ P T+T TPS T TP
Sbjct: 1521 TTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSP 1580
Query: 576 PGTSQPMPPSMGTSTSHQPATPGGGT--------AQTPEAGTSQPMPPGMGTSTSHQPTT 627
P T+ P PP++ T+T TP T TP T+ P+ P T+T TT
Sbjct: 1581 PTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTT 1640
Query: 628 PG-GGTAQTPEPGTSQPMPLSKSTPS 652
P T T P T+ P P + +TPS
Sbjct: 1641 PSPPPTTTTTPPPTTTPSPPTTTTPS 1666
Score = 95.1 bits (235), Expect = 2e-19
Identities = 78/219 (35%), Positives = 99/219 (45%), Gaps = 20/219 (9%)
Query: 437 TVTSGTATTVIEIQVSEQEPPSTDVPPSPEAGGTTGPWTSTTSEVPRPPEPSQGPSTTSS 496
T + T TT + PP+T P +P A TT P T+T P PP + TT+
Sbjct: 1483 TPSPPTTTTTTPPPTTTPSPPTT-TPITPPASTTTLPPTTT----PSPPTTT----TTTP 1533
Query: 497 GGGTGPHPPSGTTLRPPTSSTPGGPPGAENSTSHQPATPGGDTAQTPKPGTSQPMPPGVG 556
T P PP+ T + PPTS+T P + TP T +P P T+ P PP +
Sbjct: 1534 PPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSP-PTTTTPSPPTIT 1592
Query: 557 TSTSHQPATPS-GGTAQTPEPGTSQPMPPSMGTSTSHQPATPGGGTAQTPEAGTSQPMPP 615
T+T TPS T T P T+ P PP T+T P TP T P T+ P PP
Sbjct: 1593 TTTPPPTTTPSPPTTTTTTPPPTTTPSPP---TTT---PITPPTSTTTLPP--TTTPSPP 1644
Query: 616 GMGTSTSHQPTTPGGGTAQTPEPG-TSQPMPLSKSTPSS 653
T+T TTP T TP P T+ P +TPSS
Sbjct: 1645 PTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSS 1683
Score = 94.0 bits (232), Expect = 5e-19
Identities = 72/216 (33%), Positives = 95/216 (43%), Gaps = 22/216 (10%)
Query: 451 VSEQEPPSTDVPPSPEAGGTTGPWTS----TTSEVPRPPEPSQGP---STTSSGGGTGPH 503
++ PP+T P P + T P T+ TT+ PP + P +TT+ T P
Sbjct: 1396 ITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPS 1455
Query: 504 PPSGTTLRPPTSSTPGGPPGAENSTSHQPATPGGDT-----AQTPKPGTSQPMPPGVGTS 558
PP TT PP ++TP P + + P+ P T TP P T+ P+ P T+
Sbjct: 1456 PPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTT 1515
Query: 559 TSHQPATPS-GGTAQTPEPGTSQPMPPSMGTSTSHQPATPGGGTAQTPEAGTSQPMPPGM 617
T TPS T T P T+ P PP T+T P TP T P T+ P PP
Sbjct: 1516 TLPPTTTPSPPTTTTTTPPPTTTPSPP---TTT---PITPPTSTTTLPP--TTTPSPPPT 1567
Query: 618 GTSTSHQPTTPGGGTAQTPEPGT-SQPMPLSKSTPS 652
T+T TTP T TP P T + P +TPS
Sbjct: 1568 TTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPS 1603
Score = 93.6 bits (231), Expect = 7e-19
Identities = 79/252 (31%), Positives = 103/252 (40%), Gaps = 26/252 (10%)
Query: 418 TTTTLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPSTDVPPSPEAGGTTGPWTST 477
TTTT +T T+TT + + PP+T P P T P T+T
Sbjct: 1527 TTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTT--TPSPPTTT 1584
Query: 478 TSEVPR----PPEPSQGPS-----TTSSGGGTGPHPPSGTTLRPPTSSTPGGPPGAENST 528
T P P P+ PS TT+ T P PP+ T + PPTS+T P +
Sbjct: 1585 TPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPP 1644
Query: 529 SHQPATPGGDTAQTPKPGTSQPMPPGVGTSTSHQPATPSGGTAQTPEPGTSQPMPPSMGT 588
TP T +P P T+ P PP T+T TPS TP P T+ PS T
Sbjct: 1645 PTTTTTPPPTTTPSP-PTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPS-PT 1702
Query: 589 STSHQPATPGGGTAQTPEAGTSQPMPPGMGTSTSHQPTTPGGGT--------AQTPEPGT 640
+T P T T TP + T+ P PP +T TTP T T P T
Sbjct: 1703 TTPSSPIT----TTTTP-SSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLT 1757
Query: 641 SQPMPLSKSTPS 652
+ P+P S + P+
Sbjct: 1758 TTPLPPSITPPT 1769
Score = 93.2 bits (230), Expect = 9e-19
Identities = 83/251 (33%), Positives = 107/251 (42%), Gaps = 26/251 (10%)
Query: 418 TTTTLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPSTDVPPSPE---AGGTTGPW 474
TTTT +T +TT + + P +T P P + TT P
Sbjct: 1488 TTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPI 1547
Query: 475 TSTTSEVPRPPEPSQGP---STTSSGGGTGPHPPSGTTLRPPTSSTPGGPPGAENSTSHQ 531
T TS PP + P +TT+ T P PP+ TT PPT +T PP +T+
Sbjct: 1548 TPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPP----TTTPS 1603
Query: 532 PATPGGDTAQTPKPGTSQPMPPGVGTSTSHQPATPSGGTAQTPEPGTSQPMPPSMGTSTS 591
P T T T P T+ P PP T+T P TP T+ T P T+ P PP T+T
Sbjct: 1604 PPT----TTTTTPPPTTTPSPP---TTT---PITPP--TSTTTLPPTTTPSPPPTTTTTP 1651
Query: 592 HQPATPGGGTAQTPEAG-TSQPMPPGMGTSTSHQPTTPGGGTA--QTPEPGTSQPMPL-S 647
TP T TP T+ PP T +S TTP T TP P T+ P+ +
Sbjct: 1652 PPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITT 1711
Query: 648 KSTPSSGGGPS 658
+TPSS PS
Sbjct: 1712 TTTPSSTTTPS 1722
Score = 77.0 bits (188), Expect = 7e-14
Identities = 70/222 (31%), Positives = 87/222 (39%), Gaps = 39/222 (17%)
Query: 437 TVTSGTATTVIEIQVSEQEPPSTDVPPSPEAGGTTGPWTSTTSEVPRPP--EPSQGPSTT 494
T T TT + PP T P P TT P T TS PP PS P+TT
Sbjct: 1593 TTTPPPTTTPSPPTTTTTTPPPTTTPSPP----TTTPITPPTSTTTLPPTTTPSPPPTTT 1648
Query: 495 SSGGGTGPHPPSGTTLRPPTSSTPGGPPGAENSTSHQPATPGGDTAQTPKPGTSQPMPPG 554
++ PP TT PPT++TP PP +T TP TP P T+ P
Sbjct: 1649 TT-------PPPTTTPSPPTTTTP-SPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPS 1700
Query: 555 VGTSTSHQPATPSGGTAQTPEPGTSQPMPPSMGTSTSHQPATPGGGTAQTPEAGTSQPMP 614
T+T P T T TP T+ PP T T + T+ P P
Sbjct: 1701 -PTTTPSSPIT----TTTTPSSTTTPSPPP----------------TTMTTPSPTTTPSP 1739
Query: 615 PGMGTSTSHQPTTPGGGTAQTPEPGTSQP---MPLSKSTPSS 653
P T T+ PTT TP P + P P S +TP++
Sbjct: 1740 P-TTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTT 1780
Score = 75.9 bits (185), Expect = 1e-13
Identities = 100/392 (25%), Positives = 153/392 (39%), Gaps = 65/392 (16%)
Query: 415 VVLTTTTLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPSTD------VPPSPEAG 468
+ TTT + +T+ T T Q P +T V P+P
Sbjct: 4040 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 4099
Query: 469 GT----TGPWTSTTSEVPRP-PEPSQGPSTTS---------SGGGTGPHPPSGTTLRPPT 514
GT T P T+TT+ P P P +Q P+TT + TG P+ T + T
Sbjct: 4100 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 4159
Query: 515 SSTPGGPPGAENSTSHQPATPGGDTAQTPKPGTSQPMPPGVGTSTSHQPAT--------P 566
+ TP P + + P T TP P +Q PP T TS P P
Sbjct: 4160 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPP---THTSTAPIAELTTSNPPP 4216
Query: 567 SGGTAQTPEPGTSQP----------MPPSMGTSTSHQPATPGGGTAQTPEAGTSQPMPPG 616
T QT TS P +PP++ +++ P+TP TA T +G PP
Sbjct: 4217 ESSTPQTSR-STSSPLTESTTLLSTLPPAIEMTSTAPPSTP---TAPTTTSGGHTLSPP- 4271
Query: 617 MGTSTSHQPTTPGGGT----AQTPEPGTSQPMPLSKSTPSSGGGPSEDKRFSVVDMAALG 672
++T+ P TP GT + P P T Q S TP+ P+ S++ L
Sbjct: 4272 -PSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPT----PTPLSTPSIIRTTGLR 4326
Query: 673 GVLGALLLLALLGLAVLVHKHYGPRLKCCSGKAPEPQPQGFDNQAFLPDHK-ANWAPVPS 731
++L+ VL +Y P + +G + F N + + NW+ +
Sbjct: 4327 PYPSSVLI-----CCVLNDTYYAPGEEVYNGTYGD--TCYFVNCSLSCTLEFYNWSCPST 4379
Query: 732 PTHDPKPAEA-PMPAEPAPPGPASPGGAPEPP 762
P+ P P+++ P P++P+ P+ P +PP
Sbjct: 4380 PSPTPTPSKSTPTPSKPSST-PSKPTPGTKPP 4410
Score = 73.2 bits (178), Expect = 1e-12
Identities = 78/274 (28%), Positives = 103/274 (37%), Gaps = 39/274 (14%)
Query: 415 VVLTTTTLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPSTD------VPPSPEAG 468
+ TTT + +T+ T T Q P +T V P+P
Sbjct: 4017 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 4076
Query: 469 GT----TGPWTSTTSEVPRP-PEPSQGPSTTS---------SGGGTGPHPPSGTTLRPPT 514
GT T P T+TT+ P P P +Q P+TT + TG P+ T + T
Sbjct: 4077 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 4136
Query: 515 SSTPGGPPGAENSTSHQPATPGGDTAQTPKP-GTSQPMPPGVGTSTSHQPA-TPSG---- 568
+ TP P + + P T TP P GT P + T+T+ P TP+G
Sbjct: 4137 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTG 4196
Query: 569 -----GTAQTPEPGTSQPMPPSMGTSTSHQPATPGGGTAQTPEAGTSQP---MPPGMGTS 620
TA E TS P P S TS ++P T T T P M S
Sbjct: 4197 PPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPL--TESTTLLSTLPPAIEMTSTAPPS 4254
Query: 621 TSHQPTTPGGGTAQTPEPGTSQPMPLSKSTPSSG 654
T PTT GG +P P T+ P TP+ G
Sbjct: 4255 TPTAPTTTSGGHTLSPPPSTTTSPP---GTPTRG 4285
Score = 72.4 bits (176), Expect = 2e-12
Identities = 92/372 (24%), Positives = 126/372 (33%), Gaps = 43/372 (11%)
Query: 418 TTTTLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPSTDVPPSPEAGGT----TGP 473
TTTT + TVT T + + +T V P+P GT T P
Sbjct: 1887 TTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 1946
Query: 474 WTSTTSEVPRPPE-----PSQGPSTTS-----SGGGTGPHPPSGTTLRPPTSSTPGGPPG 523
T+TT+ P P P+ P TT+ + TG P+ T + T+ TP P
Sbjct: 1947 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2006
Query: 524 AENSTSHQPATPGGDTAQTPKP-GTSQPMPPGVGTSTSHQPA-TPSGGTAQTPEPGTS-- 579
+ + P T TP P GT P + T+T+ P TP+G T P T+
Sbjct: 2007 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2066
Query: 580 --QPMPPSMGTST-SHQPATPGGGTAQTP-EAGTSQPMPPGMGTSTSHQPT-TPGGGTAQ 634
P P GT T + P T TP GT P + T+T+ PT TP G
Sbjct: 2067 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2126
Query: 635 TPEPGTSQPMPLSKSTPSSGGGPSEDKRFSVVDMAALGGVLGALLLLALLGLAVLVHKHY 694
T P T+ TP+ P+ + + G
Sbjct: 2127 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-------------TQTPT 2173
Query: 695 GPRLKCCSGKAPEPQPQGFDNQAFLP-DHKANWAPVPSPTHDPKPAEAPMPA------EP 747
+ + P P P G P P P+PT P P+ P
Sbjct: 2174 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2233
Query: 748 APPGPASPGGAP 759
P G +P P
Sbjct: 2234 TPTGTQTPTTTP 2245
Score = 72.0 bits (175), Expect = 2e-12
Identities = 98/395 (24%), Positives = 137/395 (34%), Gaps = 38/395 (9%)
Query: 415 VVLTTTTLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPSTD------VPPSPEAG 468
+ TTT + +T+ T T Q P +T V P+P
Sbjct: 3902 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3961
Query: 469 GT----TGPWTSTTSEVPRP-PEPSQGPSTTS---------SGGGTGPHPPSGTTLRPPT 514
GT T P T+TT+ P P P +Q P+TT + TG P+ T + T
Sbjct: 3962 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 4021
Query: 515 SSTPGGPPGAENSTSHQPATPGGDTAQTPKP-GTSQPMPPGVGTSTSHQPA-TPSGGTAQ 572
+ TP P + + P T TP P GT P + T+T+ P TP+G
Sbjct: 4022 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 4081
Query: 573 TPEPGTSQ----PMPPSMGTST-SHQPATPGGGTAQTPE-AGTSQPMPPGMGTSTSHQPT 626
T P T+ P P GT T + P T TP GT P + T+T+ PT
Sbjct: 4082 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 4141
Query: 627 -TPGGGTAQTPEPGTSQPMPLSKSTPSSGGGPSEDKRFSVVDMAAL----GGVLGALLLL 681
TP G T P T+ TP+ P+ + + G G
Sbjct: 4142 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHT 4201
Query: 682 ALLGLAVLVHKHYGPRLKC--CSGKAPEPQPQGFDNQAFLPD--HKANWAPVPSPTHDPK 737
+ +A L + P S P + + LP + AP +PT P
Sbjct: 4202 STAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTA-PT 4260
Query: 738 PAEAPMPAEPAPPGPASPGGAPEPPAAARAGGSPT 772
P P SP G P + +PT
Sbjct: 4261 TTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPT 4295
Score = 70.9 bits (172), Expect = 5e-12
Identities = 93/382 (24%), Positives = 127/382 (33%), Gaps = 51/382 (13%)
Query: 415 VVLTTTTLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPSTD------VPPSPEAG 468
+ TTT + +T+ T T Q P +T V P+P
Sbjct: 1947 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2006
Query: 469 GT----TGPWTSTTSEVPRP-PEPSQGPSTTS---------SGGGTGPHPPSGTTLRPPT 514
GT T P T+TT+ P P P +Q P+TT + TG P+ T + T
Sbjct: 2007 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2066
Query: 515 SSTPGGPPGAENSTSHQPATPGGDTAQTPKP-GTSQPMPPGVGTSTSHQPATPSGGTAQT 573
+ TP P + + P T TP P GT P + T+T+ P TP+ QT
Sbjct: 2067 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQT 2125
Query: 574 P------EPGTSQPMPPSMGTST-SHQPATPGGGTAQTP-EAGTSQPMPPGMGTSTSHQP 625
P T P P GT T + P T TP GT P + T+T+ P
Sbjct: 2126 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2185
Query: 626 T-TPGGGTAQTPEPGTSQPMPLSKSTPSSGGGPSEDKRFSVVDMAALGGVLGALLLLALL 684
T TP G T P T+ TP+ P+ + + G
Sbjct: 2186 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-------- 2237
Query: 685 GLAVLVHKHYGPRLKCCSGKAPEPQPQGFDNQAFLP-DHKANWAPVPSPTHDPKPAEAPM 743
+ + P P P G P P P+PT P P+
Sbjct: 2238 -----TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2292
Query: 744 PA------EPAPPGPASPGGAP 759
P P G +P P
Sbjct: 2293 TTTTTVTPTPTPTGTQTPTTTP 2314
Score = 70.9 bits (172), Expect = 5e-12
Identities = 93/382 (24%), Positives = 127/382 (33%), Gaps = 51/382 (13%)
Query: 415 VVLTTTTLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPSTD------VPPSPEAG 468
+ TTT + +T+ T T Q P +T V P+P
Sbjct: 2062 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2121
Query: 469 GT----TGPWTSTTSEVPRP-PEPSQGPSTTS---------SGGGTGPHPPSGTTLRPPT 514
GT T P T+TT+ P P P +Q P+TT + TG P+ T + T
Sbjct: 2122 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2181
Query: 515 SSTPGGPPGAENSTSHQPATPGGDTAQTPKP-GTSQPMPPGVGTSTSHQPATPSGGTAQT 573
+ TP P + + P T TP P GT P + T+T+ P TP+ QT
Sbjct: 2182 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQT 2240
Query: 574 P------EPGTSQPMPPSMGTST-SHQPATPGGGTAQTP-EAGTSQPMPPGMGTSTSHQP 625
P T P P GT T + P T TP GT P + T+T+ P
Sbjct: 2241 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2300
Query: 626 T-TPGGGTAQTPEPGTSQPMPLSKSTPSSGGGPSEDKRFSVVDMAALGGVLGALLLLALL 684
T TP G T P T+ TP+ P+ + + G
Sbjct: 2301 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-------- 2352
Query: 685 GLAVLVHKHYGPRLKCCSGKAPEPQPQGFDNQAFLP-DHKANWAPVPSPTHDPKPAEAPM 743
+ + P P P G P P P+PT P P+
Sbjct: 2353 -----TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2407
Query: 744 PA------EPAPPGPASPGGAP 759
P P G +P P
Sbjct: 2408 TTTTTVTPTPTPTGTQTPTTTP 2429
Score = 70.9 bits (172), Expect = 5e-12
Identities = 93/382 (24%), Positives = 127/382 (33%), Gaps = 51/382 (13%)
Query: 415 VVLTTTTLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPSTD------VPPSPEAG 468
+ TTT + +T+ T T Q P +T V P+P
Sbjct: 2177 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2236
Query: 469 GT----TGPWTSTTSEVPRP-PEPSQGPSTTS---------SGGGTGPHPPSGTTLRPPT 514
GT T P T+TT+ P P P +Q P+TT + TG P+ T + T
Sbjct: 2237 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2296
Query: 515 SSTPGGPPGAENSTSHQPATPGGDTAQTPKP-GTSQPMPPGVGTSTSHQPATPSGGTAQT 573
+ TP P + + P T TP P GT P + T+T+ P TP+ QT
Sbjct: 2297 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQT 2355
Query: 574 P------EPGTSQPMPPSMGTST-SHQPATPGGGTAQTP-EAGTSQPMPPGMGTSTSHQP 625
P T P P GT T + P T TP GT P + T+T+ P
Sbjct: 2356 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2415
Query: 626 T-TPGGGTAQTPEPGTSQPMPLSKSTPSSGGGPSEDKRFSVVDMAALGGVLGALLLLALL 684
T TP G T P T+ TP+ P+ + + G
Sbjct: 2416 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-------- 2467
Query: 685 GLAVLVHKHYGPRLKCCSGKAPEPQPQGFDNQAFLP-DHKANWAPVPSPTHDPKPAEAPM 743
+ + P P P G P P P+PT P P+
Sbjct: 2468 -----TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2522
Query: 744 PA------EPAPPGPASPGGAP 759
P P G +P P
Sbjct: 2523 TTTTTVTPTPTPTGTQTPTTTP 2544
Score = 70.9 bits (172), Expect = 5e-12
Identities = 93/382 (24%), Positives = 127/382 (33%), Gaps = 51/382 (13%)
Query: 415 VVLTTTTLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPSTD------VPPSPEAG 468
+ TTT + +T+ T T Q P +T V P+P
Sbjct: 2292 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2351
Query: 469 GT----TGPWTSTTSEVPRP-PEPSQGPSTTS---------SGGGTGPHPPSGTTLRPPT 514
GT T P T+TT+ P P P +Q P+TT + TG P+ T + T
Sbjct: 2352 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2411
Query: 515 SSTPGGPPGAENSTSHQPATPGGDTAQTPKP-GTSQPMPPGVGTSTSHQPATPSGGTAQT 573
+ TP P + + P T TP P GT P + T+T+ P TP+ QT
Sbjct: 2412 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQT 2470
Query: 574 P------EPGTSQPMPPSMGTST-SHQPATPGGGTAQTP-EAGTSQPMPPGMGTSTSHQP 625
P T P P GT T + P T TP GT P + T+T+ P
Sbjct: 2471 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2530
Query: 626 T-TPGGGTAQTPEPGTSQPMPLSKSTPSSGGGPSEDKRFSVVDMAALGGVLGALLLLALL 684
T TP G T P T+ TP+ P+ + + G
Sbjct: 2531 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-------- 2582
Query: 685 GLAVLVHKHYGPRLKCCSGKAPEPQPQGFDNQAFLP-DHKANWAPVPSPTHDPKPAEAPM 743
+ + P P P G P P P+PT P P+
Sbjct: 2583 -----TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2637
Query: 744 PA------EPAPPGPASPGGAP 759
P P G +P P
Sbjct: 2638 TTTTTVTPTPTPTGTQTPTTTP 2659
Score = 70.9 bits (172), Expect = 5e-12
Identities = 93/382 (24%), Positives = 127/382 (33%), Gaps = 51/382 (13%)
Query: 415 VVLTTTTLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPSTD------VPPSPEAG 468
+ TTT + +T+ T T Q P +T V P+P
Sbjct: 2407 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2466
Query: 469 GT----TGPWTSTTSEVPRP-PEPSQGPSTTS---------SGGGTGPHPPSGTTLRPPT 514
GT T P T+TT+ P P P +Q P+TT + TG P+ T + T
Sbjct: 2467 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2526
Query: 515 SSTPGGPPGAENSTSHQPATPGGDTAQTPKP-GTSQPMPPGVGTSTSHQPATPSGGTAQT 573
+ TP P + + P T TP P GT P + T+T+ P TP+ QT
Sbjct: 2527 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQT 2585
Query: 574 P------EPGTSQPMPPSMGTST-SHQPATPGGGTAQTP-EAGTSQPMPPGMGTSTSHQP 625
P T P P GT T + P T TP GT P + T+T+ P
Sbjct: 2586 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2645
Query: 626 T-TPGGGTAQTPEPGTSQPMPLSKSTPSSGGGPSEDKRFSVVDMAALGGVLGALLLLALL 684
T TP G T P T+ TP+ P+ + + G
Sbjct: 2646 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-------- 2697
Query: 685 GLAVLVHKHYGPRLKCCSGKAPEPQPQGFDNQAFLP-DHKANWAPVPSPTHDPKPAEAPM 743
+ + P P P G P P P+PT P P+
Sbjct: 2698 -----TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2752
Query: 744 PA------EPAPPGPASPGGAP 759
P P G +P P
Sbjct: 2753 TTTTTVTPTPTPTGTQTPTTTP 2774
Score = 70.9 bits (172), Expect = 5e-12
Identities = 93/382 (24%), Positives = 127/382 (33%), Gaps = 51/382 (13%)
Query: 415 VVLTTTTLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPSTD------VPPSPEAG 468
+ TTT + +T+ T T Q P +T V P+P
Sbjct: 2522 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2581
Query: 469 GT----TGPWTSTTSEVPRP-PEPSQGPSTTS---------SGGGTGPHPPSGTTLRPPT 514
GT T P T+TT+ P P P +Q P+TT + TG P+ T + T
Sbjct: 2582 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2641
Query: 515 SSTPGGPPGAENSTSHQPATPGGDTAQTPKP-GTSQPMPPGVGTSTSHQPATPSGGTAQT 573
+ TP P + + P T TP P GT P + T+T+ P TP+ QT
Sbjct: 2642 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQT 2700
Query: 574 P------EPGTSQPMPPSMGTST-SHQPATPGGGTAQTP-EAGTSQPMPPGMGTSTSHQP 625
P T P P GT T + P T TP GT P + T+T+ P
Sbjct: 2701 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2760
Query: 626 T-TPGGGTAQTPEPGTSQPMPLSKSTPSSGGGPSEDKRFSVVDMAALGGVLGALLLLALL 684
T TP G T P T+ TP+ P+ + + G
Sbjct: 2761 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-------- 2812
Query: 685 GLAVLVHKHYGPRLKCCSGKAPEPQPQGFDNQAFLP-DHKANWAPVPSPTHDPKPAEAPM 743
+ + P P P G P P P+PT P P+
Sbjct: 2813 -----TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2867
Query: 744 PA------EPAPPGPASPGGAP 759
P P G +P P
Sbjct: 2868 TTTTTVTPTPTPTGTQTPTTTP 2889
Score = 70.9 bits (172), Expect = 5e-12
Identities = 93/382 (24%), Positives = 127/382 (33%), Gaps = 51/382 (13%)
Query: 415 VVLTTTTLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPSTD------VPPSPEAG 468
+ TTT + +T+ T T Q P +T V P+P
Sbjct: 2637 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2696
Query: 469 GT----TGPWTSTTSEVPRP-PEPSQGPSTTS---------SGGGTGPHPPSGTTLRPPT 514
GT T P T+TT+ P P P +Q P+TT + TG P+ T + T
Sbjct: 2697 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2756
Query: 515 SSTPGGPPGAENSTSHQPATPGGDTAQTPKP-GTSQPMPPGVGTSTSHQPATPSGGTAQT 573
+ TP P + + P T TP P GT P + T+T+ P TP+ QT
Sbjct: 2757 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQT 2815
Query: 574 P------EPGTSQPMPPSMGTST-SHQPATPGGGTAQTP-EAGTSQPMPPGMGTSTSHQP 625
P T P P GT T + P T TP GT P + T+T+ P
Sbjct: 2816 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2875
Query: 626 T-TPGGGTAQTPEPGTSQPMPLSKSTPSSGGGPSEDKRFSVVDMAALGGVLGALLLLALL 684
T TP G T P T+ TP+ P+ + + G
Sbjct: 2876 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-------- 2927
Query: 685 GLAVLVHKHYGPRLKCCSGKAPEPQPQGFDNQAFLP-DHKANWAPVPSPTHDPKPAEAPM 743
+ + P P P G P P P+PT P P+
Sbjct: 2928 -----TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2982
Query: 744 PA------EPAPPGPASPGGAP 759
P P G +P P
Sbjct: 2983 TTTTTVTPTPTPTGTQTPTTTP 3004
Score = 70.9 bits (172), Expect = 5e-12
Identities = 93/382 (24%), Positives = 127/382 (33%), Gaps = 51/382 (13%)
Query: 415 VVLTTTTLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPSTD------VPPSPEAG 468
+ TTT + +T+ T T Q P +T V P+P
Sbjct: 2752 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2811
Query: 469 GT----TGPWTSTTSEVPRP-PEPSQGPSTTS---------SGGGTGPHPPSGTTLRPPT 514
GT T P T+TT+ P P P +Q P+TT + TG P+ T + T
Sbjct: 2812 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2871
Query: 515 SSTPGGPPGAENSTSHQPATPGGDTAQTPKP-GTSQPMPPGVGTSTSHQPATPSGGTAQT 573
+ TP P + + P T TP P GT P + T+T+ P TP+ QT
Sbjct: 2872 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQT 2930
Query: 574 P------EPGTSQPMPPSMGTST-SHQPATPGGGTAQTP-EAGTSQPMPPGMGTSTSHQP 625
P T P P GT T + P T TP GT P + T+T+ P
Sbjct: 2931 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2990
Query: 626 T-TPGGGTAQTPEPGTSQPMPLSKSTPSSGGGPSEDKRFSVVDMAALGGVLGALLLLALL 684
T TP G T P T+ TP+ P+ + + G
Sbjct: 2991 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-------- 3042
Query: 685 GLAVLVHKHYGPRLKCCSGKAPEPQPQGFDNQAFLP-DHKANWAPVPSPTHDPKPAEAPM 743
+ + P P P G P P P+PT P P+
Sbjct: 3043 -----TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3097
Query: 744 PA------EPAPPGPASPGGAP 759
P P G +P P
Sbjct: 3098 TTTTTVTPTPTPTGTQTPTTTP 3119
Score = 70.9 bits (172), Expect = 5e-12
Identities = 93/382 (24%), Positives = 127/382 (33%), Gaps = 51/382 (13%)
Query: 415 VVLTTTTLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPSTD------VPPSPEAG 468
+ TTT + +T+ T T Q P +T V P+P
Sbjct: 2867 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2926
Query: 469 GT----TGPWTSTTSEVPRP-PEPSQGPSTTS---------SGGGTGPHPPSGTTLRPPT 514
GT T P T+TT+ P P P +Q P+TT + TG P+ T + T
Sbjct: 2927 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2986
Query: 515 SSTPGGPPGAENSTSHQPATPGGDTAQTPKP-GTSQPMPPGVGTSTSHQPATPSGGTAQT 573
+ TP P + + P T TP P GT P + T+T+ P TP+ QT
Sbjct: 2987 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQT 3045
Query: 574 P------EPGTSQPMPPSMGTST-SHQPATPGGGTAQTP-EAGTSQPMPPGMGTSTSHQP 625
P T P P GT T + P T TP GT P + T+T+ P
Sbjct: 3046 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3105
Query: 626 T-TPGGGTAQTPEPGTSQPMPLSKSTPSSGGGPSEDKRFSVVDMAALGGVLGALLLLALL 684
T TP G T P T+ TP+ P+ + + G
Sbjct: 3106 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-------- 3157
Query: 685 GLAVLVHKHYGPRLKCCSGKAPEPQPQGFDNQAFLP-DHKANWAPVPSPTHDPKPAEAPM 743
+ + P P P G P P P+PT P P+
Sbjct: 3158 -----TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3212
Query: 744 PA------EPAPPGPASPGGAP 759
P P G +P P
Sbjct: 3213 TTTTTVTPTPTPTGTQTPTTTP 3234
Score = 70.9 bits (172), Expect = 5e-12
Identities = 93/382 (24%), Positives = 127/382 (33%), Gaps = 51/382 (13%)
Query: 415 VVLTTTTLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPSTD------VPPSPEAG 468
+ TTT + +T+ T T Q P +T V P+P
Sbjct: 2982 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3041
Query: 469 GT----TGPWTSTTSEVPRP-PEPSQGPSTTS---------SGGGTGPHPPSGTTLRPPT 514
GT T P T+TT+ P P P +Q P+TT + TG P+ T + T
Sbjct: 3042 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3101
Query: 515 SSTPGGPPGAENSTSHQPATPGGDTAQTPKP-GTSQPMPPGVGTSTSHQPATPSGGTAQT 573
+ TP P + + P T TP P GT P + T+T+ P TP+ QT
Sbjct: 3102 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQT 3160
Query: 574 P------EPGTSQPMPPSMGTST-SHQPATPGGGTAQTP-EAGTSQPMPPGMGTSTSHQP 625
P T P P GT T + P T TP GT P + T+T+ P
Sbjct: 3161 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3220
Query: 626 T-TPGGGTAQTPEPGTSQPMPLSKSTPSSGGGPSEDKRFSVVDMAALGGVLGALLLLALL 684
T TP G T P T+ TP+ P+ + + G
Sbjct: 3221 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-------- 3272
Query: 685 GLAVLVHKHYGPRLKCCSGKAPEPQPQGFDNQAFLP-DHKANWAPVPSPTHDPKPAEAPM 743
+ + P P P G P P P+PT P P+
Sbjct: 3273 -----TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3327
Query: 744 PA------EPAPPGPASPGGAP 759
P P G +P P
Sbjct: 3328 TTTTTVTPTPTPTGTQTPTTTP 3349
Score = 70.9 bits (172), Expect = 5e-12
Identities = 93/382 (24%), Positives = 127/382 (33%), Gaps = 51/382 (13%)
Query: 415 VVLTTTTLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPSTD------VPPSPEAG 468
+ TTT + +T+ T T Q P +T V P+P
Sbjct: 3097 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3156
Query: 469 GT----TGPWTSTTSEVPRP-PEPSQGPSTTS---------SGGGTGPHPPSGTTLRPPT 514
GT T P T+TT+ P P P +Q P+TT + TG P+ T + T
Sbjct: 3157 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3216
Query: 515 SSTPGGPPGAENSTSHQPATPGGDTAQTPKP-GTSQPMPPGVGTSTSHQPATPSGGTAQT 573
+ TP P + + P T TP P GT P + T+T+ P TP+ QT
Sbjct: 3217 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQT 3275
Query: 574 P------EPGTSQPMPPSMGTST-SHQPATPGGGTAQTP-EAGTSQPMPPGMGTSTSHQP 625
P T P P GT T + P T TP GT P + T+T+ P
Sbjct: 3276 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3335
Query: 626 T-TPGGGTAQTPEPGTSQPMPLSKSTPSSGGGPSEDKRFSVVDMAALGGVLGALLLLALL 684
T TP G T P T+ TP+ P+ + + G
Sbjct: 3336 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-------- 3387
Query: 685 GLAVLVHKHYGPRLKCCSGKAPEPQPQGFDNQAFLP-DHKANWAPVPSPTHDPKPAEAPM 743
+ + P P P G P P P+PT P P+
Sbjct: 3388 -----TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3442
Query: 744 PA------EPAPPGPASPGGAP 759
P P G +P P
Sbjct: 3443 TTTTTVTPTPTPTGTQTPTTTP 3464
Score = 70.9 bits (172), Expect = 5e-12
Identities = 93/382 (24%), Positives = 127/382 (33%), Gaps = 51/382 (13%)
Query: 415 VVLTTTTLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPSTD------VPPSPEAG 468
+ TTT + +T+ T T Q P +T V P+P
Sbjct: 3212 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3271
Query: 469 GT----TGPWTSTTSEVPRP-PEPSQGPSTTS---------SGGGTGPHPPSGTTLRPPT 514
GT T P T+TT+ P P P +Q P+TT + TG P+ T + T
Sbjct: 3272 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3331
Query: 515 SSTPGGPPGAENSTSHQPATPGGDTAQTPKP-GTSQPMPPGVGTSTSHQPATPSGGTAQT 573
+ TP P + + P T TP P GT P + T+T+ P TP+ QT
Sbjct: 3332 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQT 3390
Query: 574 P------EPGTSQPMPPSMGTST-SHQPATPGGGTAQTP-EAGTSQPMPPGMGTSTSHQP 625
P T P P GT T + P T TP GT P + T+T+ P
Sbjct: 3391 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3450
Query: 626 T-TPGGGTAQTPEPGTSQPMPLSKSTPSSGGGPSEDKRFSVVDMAALGGVLGALLLLALL 684
T TP G T P T+ TP+ P+ + + G
Sbjct: 3451 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-------- 3502
Query: 685 GLAVLVHKHYGPRLKCCSGKAPEPQPQGFDNQAFLP-DHKANWAPVPSPTHDPKPAEAPM 743
+ + P P P G P P P+PT P P+
Sbjct: 3503 -----TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3557
Query: 744 PA------EPAPPGPASPGGAP 759
P P G +P P
Sbjct: 3558 TTTTTVTPTPTPTGTQTPTTTP 3579
Score = 70.9 bits (172), Expect = 5e-12
Identities = 93/382 (24%), Positives = 127/382 (33%), Gaps = 51/382 (13%)
Query: 415 VVLTTTTLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPSTD------VPPSPEAG 468
+ TTT + +T+ T T Q P +T V P+P
Sbjct: 3327 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3386
Query: 469 GT----TGPWTSTTSEVPRP-PEPSQGPSTTS---------SGGGTGPHPPSGTTLRPPT 514
GT T P T+TT+ P P P +Q P+TT + TG P+ T + T
Sbjct: 3387 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3446
Query: 515 SSTPGGPPGAENSTSHQPATPGGDTAQTPKP-GTSQPMPPGVGTSTSHQPATPSGGTAQT 573
+ TP P + + P T TP P GT P + T+T+ P TP+ QT
Sbjct: 3447 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQT 3505
Query: 574 P------EPGTSQPMPPSMGTST-SHQPATPGGGTAQTP-EAGTSQPMPPGMGTSTSHQP 625
P T P P GT T + P T TP GT P + T+T+ P
Sbjct: 3506 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3565
Query: 626 T-TPGGGTAQTPEPGTSQPMPLSKSTPSSGGGPSEDKRFSVVDMAALGGVLGALLLLALL 684
T TP G T P T+ TP+ P+ + + G
Sbjct: 3566 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-------- 3617
Query: 685 GLAVLVHKHYGPRLKCCSGKAPEPQPQGFDNQAFLP-DHKANWAPVPSPTHDPKPAEAPM 743
+ + P P P G P P P+PT P P+
Sbjct: 3618 -----TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3672
Query: 744 PA------EPAPPGPASPGGAP 759
P P G +P P
Sbjct: 3673 TTTTTVTPTPTPTGTQTPTTTP 3694
Score = 70.9 bits (172), Expect = 5e-12
Identities = 93/382 (24%), Positives = 127/382 (33%), Gaps = 51/382 (13%)
Query: 415 VVLTTTTLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPSTD------VPPSPEAG 468
+ TTT + +T+ T T Q P +T V P+P
Sbjct: 3442 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3501
Query: 469 GT----TGPWTSTTSEVPRP-PEPSQGPSTTS---------SGGGTGPHPPSGTTLRPPT 514
GT T P T+TT+ P P P +Q P+TT + TG P+ T + T
Sbjct: 3502 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3561
Query: 515 SSTPGGPPGAENSTSHQPATPGGDTAQTPKP-GTSQPMPPGVGTSTSHQPATPSGGTAQT 573
+ TP P + + P T TP P GT P + T+T+ P TP+ QT
Sbjct: 3562 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQT 3620
Query: 574 P------EPGTSQPMPPSMGTST-SHQPATPGGGTAQTP-EAGTSQPMPPGMGTSTSHQP 625
P T P P GT T + P T TP GT P + T+T+ P
Sbjct: 3621 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3680
Query: 626 T-TPGGGTAQTPEPGTSQPMPLSKSTPSSGGGPSEDKRFSVVDMAALGGVLGALLLLALL 684
T TP G T P T+ TP+ P+ + + G
Sbjct: 3681 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-------- 3732
Query: 685 GLAVLVHKHYGPRLKCCSGKAPEPQPQGFDNQAFLP-DHKANWAPVPSPTHDPKPAEAPM 743
+ + P P P G P P P+PT P P+
Sbjct: 3733 -----TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3787
Query: 744 PA------EPAPPGPASPGGAP 759
P P G +P P
Sbjct: 3788 TTTTTVTPTPTPTGTQTPTTTP 3809
Score = 70.9 bits (172), Expect = 5e-12
Identities = 93/382 (24%), Positives = 127/382 (33%), Gaps = 51/382 (13%)
Query: 415 VVLTTTTLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPSTD------VPPSPEAG 468
+ TTT + +T+ T T Q P +T V P+P
Sbjct: 3557 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3616
Query: 469 GT----TGPWTSTTSEVPRP-PEPSQGPSTTS---------SGGGTGPHPPSGTTLRPPT 514
GT T P T+TT+ P P P +Q P+TT + TG P+ T + T
Sbjct: 3617 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3676
Query: 515 SSTPGGPPGAENSTSHQPATPGGDTAQTPKP-GTSQPMPPGVGTSTSHQPATPSGGTAQT 573
+ TP P + + P T TP P GT P + T+T+ P TP+ QT
Sbjct: 3677 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQT 3735
Query: 574 P------EPGTSQPMPPSMGTST-SHQPATPGGGTAQTP-EAGTSQPMPPGMGTSTSHQP 625
P T P P GT T + P T TP GT P + T+T+ P
Sbjct: 3736 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3795
Query: 626 T-TPGGGTAQTPEPGTSQPMPLSKSTPSSGGGPSEDKRFSVVDMAALGGVLGALLLLALL 684
T TP G T P T+ TP+ P+ + + G
Sbjct: 3796 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-------- 3847
Query: 685 GLAVLVHKHYGPRLKCCSGKAPEPQPQGFDNQAFLP-DHKANWAPVPSPTHDPKPAEAPM 743
+ + P P P G P P P+PT P P+
Sbjct: 3848 -----TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3902
Query: 744 PA------EPAPPGPASPGGAP 759
P P G +P P
Sbjct: 3903 TTTTTVTPTPTPTGTQTPTTTP 3924
Score = 70.9 bits (172), Expect = 5e-12
Identities = 93/382 (24%), Positives = 127/382 (33%), Gaps = 51/382 (13%)
Query: 415 VVLTTTTLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPSTD------VPPSPEAG 468
+ TTT + +T+ T T Q P +T V P+P
Sbjct: 3672 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3731
Query: 469 GT----TGPWTSTTSEVPRP-PEPSQGPSTTS---------SGGGTGPHPPSGTTLRPPT 514
GT T P T+TT+ P P P +Q P+TT + TG P+ T + T
Sbjct: 3732 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3791
Query: 515 SSTPGGPPGAENSTSHQPATPGGDTAQTPKP-GTSQPMPPGVGTSTSHQPATPSGGTAQT 573
+ TP P + + P T TP P GT P + T+T+ P TP+ QT
Sbjct: 3792 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQT 3850
Query: 574 P------EPGTSQPMPPSMGTST-SHQPATPGGGTAQTP-EAGTSQPMPPGMGTSTSHQP 625
P T P P GT T + P T TP GT P + T+T+ P
Sbjct: 3851 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3910
Query: 626 T-TPGGGTAQTPEPGTSQPMPLSKSTPSSGGGPSEDKRFSVVDMAALGGVLGALLLLALL 684
T TP G T P T+ TP+ P+ + + G
Sbjct: 3911 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-------- 3962
Query: 685 GLAVLVHKHYGPRLKCCSGKAPEPQPQGFDNQAFLP-DHKANWAPVPSPTHDPKPAEAPM 743
+ + P P P G P P P+PT P P+
Sbjct: 3963 -----TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4017
Query: 744 PA------EPAPPGPASPGGAP 759
P P G +P P
Sbjct: 4018 TTTTTVTPTPTPTGTQTPTTTP 4039
Score = 70.9 bits (172), Expect = 5e-12
Identities = 93/382 (24%), Positives = 127/382 (33%), Gaps = 51/382 (13%)
Query: 415 VVLTTTTLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPSTD------VPPSPEAG 468
+ TTT + +T+ T T Q P +T V P+P
Sbjct: 3787 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3846
Query: 469 GT----TGPWTSTTSEVPRP-PEPSQGPSTTS---------SGGGTGPHPPSGTTLRPPT 514
GT T P T+TT+ P P P +Q P+TT + TG P+ T + T
Sbjct: 3847 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3906
Query: 515 SSTPGGPPGAENSTSHQPATPGGDTAQTPKP-GTSQPMPPGVGTSTSHQPATPSGGTAQT 573
+ TP P + + P T TP P GT P + T+T+ P TP+ QT
Sbjct: 3907 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQT 3965
Query: 574 P------EPGTSQPMPPSMGTST-SHQPATPGGGTAQTP-EAGTSQPMPPGMGTSTSHQP 625
P T P P GT T + P T TP GT P + T+T+ P
Sbjct: 3966 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4025
Query: 626 T-TPGGGTAQTPEPGTSQPMPLSKSTPSSGGGPSEDKRFSVVDMAALGGVLGALLLLALL 684
T TP G T P T+ TP+ P+ + + G
Sbjct: 4026 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-------- 4077
Query: 685 GLAVLVHKHYGPRLKCCSGKAPEPQPQGFDNQAFLP-DHKANWAPVPSPTHDPKPAEAPM 743
+ + P P P G P P P+PT P P+
Sbjct: 4078 -----TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4132
Query: 744 PA------EPAPPGPASPGGAP 759
P P G +P P
Sbjct: 4133 TTTTTVTPTPTPTGTQTPTTTP 4154
Score = 68.9 bits (167), Expect = 2e-11
Identities = 88/353 (24%), Positives = 120/353 (33%), Gaps = 50/353 (14%)
Query: 444 TTVIEIQVSEQEPPSTD-------VPPSPEAGGT----TGPWTSTTSEVPRPPE-----P 487
TT+ PP+T V P+P GT T P T+TT+ P P P
Sbjct: 1883 TTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 1942
Query: 488 SQGPSTTS-----SGGGTGPHPPSGTTLRPPTSSTPGGPPGAENSTSHQPATPGGDTAQT 542
+ P TT+ + TG P+ T + T+ TP P + + P T T
Sbjct: 1943 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2002
Query: 543 PKP-GTSQPMPPGVGTSTSHQPA-TPSGGTAQTPEPGTS----QPMPPSMGTST-SHQPA 595
P P GT P + T+T+ P TP+G T P T+ P P GT T + P
Sbjct: 2003 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2062
Query: 596 TPGGGTAQTP-EAGTSQPMPPGMGTSTSHQPT-TPGGGTAQTPEPGTSQPMPLSKSTPSS 653
T TP GT P + T+T+ PT TP G T P T+ TP+
Sbjct: 2063 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2122
Query: 654 GGGPSEDKRFSVVDMAALGGVLGALLLLALLGLAVLVHKHYGPRLKCCSGKAPEPQPQGF 713
P+ + + G + + P P P G
Sbjct: 2123 TQTPTTTPITTTTTVTPTPTPTG-------------TQTPTTTPITTTTTVTPTPTPTGT 2169
Query: 714 DNQAFLP-DHKANWAPVPSPTHDPKPAEAPMPA------EPAPPGPASPGGAP 759
P P P+PT P P+ P P G +P P
Sbjct: 2170 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2222
Score = 68.2 bits (165), Expect = 3e-11
Identities = 56/182 (30%), Positives = 75/182 (41%), Gaps = 8/182 (4%)
Query: 418 TTTTLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPSTDVPPSPEAGGTTGPWTST 477
TTTT +T T+TT + + PP+T P P T P T+T
Sbjct: 1606 TTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTT--TPSPPTTT 1663
Query: 478 TSEVPRPPEPSQGPSTT-SSGGGTGPHPPSGTTLRPPTSSTPGGP-PGAENSTSHQPATP 535
T P + P+TT SS T P PP+ T P ++TP P +S +P
Sbjct: 1664 TPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSP 1723
Query: 536 GGDTAQTPKPGTSQPMPPGVGTSTSHQPATPSGGTAQTPEPGTSQPMPPSMGTSTSHQPA 595
T TP P T+ P PP T T+ P T S TP P + PP+ ++ P
Sbjct: 1724 PPTTMTTPSP-TTTPSPP-TTTMTTLPPTTTSSPLTTTPLPPSI--TPPTFSPFSTTTPT 1779
Query: 596 TP 597
TP
Sbjct: 1780 TP 1781
Score = 67.0 bits (162), Expect = 7e-11
Identities = 71/279 (25%), Positives = 90/279 (32%), Gaps = 35/279 (12%)
Query: 500 TGPHPPSGTTLRPPTSSTPGGPPGAENSTSHQPATPGGDTAQTPKPGTSQPMPPGVGTST 559
T P PP+ T PPTS+T P +T+ P T T T P T+ P PP T+T
Sbjct: 1397 TTPSPPTTTPSPPPTSTTTLPP-----TTTPSPPT----TTTTTPPPTTTPSPPITTTTT 1447
Query: 560 SHQPATPSG--GTAQTPEPGTSQPMPPSMGTSTSHQPATPGGGTAQTPEAGTSQPMPPGM 617
TPS T TP P T+ P PP T+T P T T P T+ P P
Sbjct: 1448 PPPTTTPSPPISTTTTPPP-TTTPSPP---TTTPSPPTT----TPSPPTTTTTTPPPTTT 1499
Query: 618 GTSTSHQPTTPGGGTAQTPEPGTSQPMPLSKSTPSSGGGPSEDKRFSVVDMAALGGVLGA 677
+ + P TP T P T P + +TP PS + +
Sbjct: 1500 PSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTS------- 1552
Query: 678 LLLLALLGLAVLVHKHYGPRLKCCSGKAPEPQPQGFDNQAFLPDHKANWAPVPSPTHDPK 737
+ P + P P P P PT P
Sbjct: 1553 ---------TTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPS 1603
Query: 738 PAEAPMPAEPAPPGPASPGGAPEPPAAARAGGSPTAVRS 776
P P P+ P P P + PT S
Sbjct: 1604 PPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPS 1642
Score = 66.2 bits (160), Expect = 1e-10
Identities = 77/310 (24%), Positives = 105/310 (33%), Gaps = 34/310 (10%)
Query: 471 TGPWTSTTSEVPRPPEPSQGPSTTS-----SGGGTGPHPPSGTTLRPPTSSTPGGPPGAE 525
T P T TT+ P P+ P TT+ + TG P+ T + T+ TP P
Sbjct: 1880 TQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 1939
Query: 526 NSTSHQPATPGGDTAQTPKP-GTSQPMPPGVGTSTSHQPA-TPSGGTAQTPEPGTS---- 579
+ + P T TP P GT P + T+T+ P TP+G T P T+
Sbjct: 1940 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 1999
Query: 580 QPMPPSMGTST-SHQPATPGGGTAQTP-EAGTSQPMPPGMGTSTSHQPT-TPGGGTAQTP 636
P P GT T + P T TP GT P + T+T+ PT TP G T
Sbjct: 2000 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2059
Query: 637 EPGTSQPMPLSKSTPSSGGGPSEDKRFSVVDMAALGGVLGALLLLALLGLAVLVHKHYGP 696
P T+ TP+ P+ + + G
Sbjct: 2060 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-------------TQTPTTT 2106
Query: 697 RLKCCSGKAPEPQPQGFDNQAFLP-DHKANWAPVPSPTHDPKPAEAPMPA------EPAP 749
+ + P P P G P P P+PT P P+ P P
Sbjct: 2107 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2166
Query: 750 PGPASPGGAP 759
G +P P
Sbjct: 2167 TGTQTPTTTP 2176
Score = 54.7 bits (130), Expect = 4e-07
Identities = 85/365 (23%), Positives = 119/365 (32%), Gaps = 63/365 (17%)
Query: 437 TVTSGTATTVIEIQVSEQEPPSTDVPPSPEAGGTTGPWTSTTSEVPRPPEPSQGPSTTSS 496
T+T+ + TT ++ PS+ PSP T P +TT P + P+TTSS
Sbjct: 1695 TMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSS 1754
Query: 497 GGGTGPHPPSGT--TLRPPTSSTPGGP-------PGAENSTSHQPATPGGDT---AQTPK 544
T P PPS T T P +++TP P G +S PGGDT
Sbjct: 1755 PLTTTPLPPSITPPTFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVCG 1814
Query: 545 PGTSQPMPPGVGTSTSHQPATPSGGTAQT---------------PEPGTSQPMPPSMGTS 589
PG + + + P P G QT +PG PM +
Sbjct: 1815 PGWAA----NISCRATMYPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYE 1870
Query: 590 TS-------HQPATPGGGTAQTPEAGTSQPMPPGMGTSTSHQPT-TPGGGTAQTPEPGTS 641
+ QP T T + P T+ P+ T+T+ PT TP G T P T+
Sbjct: 1871 INVQCCECVTQPTTMTTTTTENPTPPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITT 1926
Query: 642 QPMPLSKSTPSSGGGPSEDKRFSVVDMAALGGVLGALLLLALLGLAVLVHKHYGPRLKCC 701
TP+ P+ + + G +
Sbjct: 1927 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-------------TQTPTTTPITTT 1973
Query: 702 SGKAPEPQPQGFDNQAFLP-DHKANWAPVPSPTHDPKPAEAPMPA------EPAPPGPAS 754
+ P P P G P P P+PT P P+ P P G +
Sbjct: 1974 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2033
Query: 755 PGGAP 759
P P
Sbjct: 2034 PTTTP 2038
Score = 49.7 bits (117), Expect = 1e-05
Identities = 40/138 (28%), Positives = 56/138 (40%), Gaps = 9/138 (6%)
Query: 437 TVTSGTATTVIEIQVSEQEPPSTDVPPSPEAGGTTGPWTSTTSEVPRPPEPSQGPSTTSS 496
T + T TT + PP T P SP + P T+ T+ P S +TT+
Sbjct: 1656 TPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTP 1715
Query: 497 GGGTGPHPPSGTTLRPPTSSTPGGPPGAENSTSHQPATPGGDTAQTPKPGTSQPMPPGVG 556
T P PP TT+ P+ +T PP T+ P T T P T+ P+PP +
Sbjct: 1716 SSTTTPSPPP-TTMTTPSPTTTPSPP-TTTMTTLPPTT-------TSSPLTTTPLPPSIT 1766
Query: 557 TSTSHQPATPSGGTAQTP 574
T +T + T P
Sbjct: 1767 PPTFSPFSTTTPTTPCVP 1784
>gi|20143482 melanoma antigen family E, 1 [Homo sapiens]
Length = 957
Score = 92.4 bits (228), Expect = 2e-18
Identities = 115/359 (32%), Positives = 142/359 (39%), Gaps = 71/359 (19%)
Query: 430 AEVEAHNTVTSGTATTVIEIQV--SEQEPPSTDVPPSPEAGGTT--------GPWTSTTS 479
A E NT T++ V + E PST +PP+P G +T GP TS
Sbjct: 131 AASEGRNTSRPPTSSEEPSTSVPPTASEVPSTSLPPTPGEGTSTSVPPTAYEGPSTSVV- 189
Query: 480 EVPRPPEPSQGPSTT---SSGGGTGPHPPSGTT--LRPPTSSTPGGPPGAENSTSHQP-A 533
P P +GPST+ + G G G P T L +TP P STS P A
Sbjct: 190 -----PTPDEGPSTSVLPTPGEGPGTSVPLAATEGLSTSVQATPDEGP----STSVPPTA 240
Query: 534 TPGGDTAQTPK----PGTSQPMPPGVGTSTSHQPATPSG---GTAQTPEPGTSQPMPPSM 586
T G T P P TS P PG G STS PA G T G+S +PP+
Sbjct: 241 TEGLSTPVPPTRDEGPSTSVPATPGEGPSTSVLPAASDGQSISLVPTRGKGSSTSVPPTA 300
Query: 587 --GTSTSHQPA-----------TPGGGTA------QTPEAGTSQPMPPGMGTSTSHQPTT 627
G STS QP TPGGG + T E TS P PG G STS P
Sbjct: 301 TEGLSTSVQPTAGEGSSTSVPPTPGGGLSTSVPPTATEELSTSVPPTPGEGPSTSVLP-I 359
Query: 628 PGGGTAQTPEPGTSQPMPLSKSTPSSGGGPSEDKRFSVVDMAALGGVLGALLLLALLGLA 687
PG G + T P T+ + P+ G G S ++V A G G +
Sbjct: 360 PGEGLS-TSVPPTASDGSDTSVPPTPGEGAS-----TLVQPTAPDGP----------GSS 403
Query: 688 VLVHKHYGPRLKCCSGKAPEPQPQGFDNQAFLPDHKANWAPVPSPTHDPKPAEAPMPAE 746
VL + GP S + + P LP + A V S + PK AE P+ E
Sbjct: 404 VLPNPGEGPSTLFSSSASVDRNPS--KCSLVLPSPRVTKASVDSDSEGPKGAEGPIEFE 460
Score = 63.5 bits (153), Expect = 8e-10
Identities = 109/395 (27%), Positives = 137/395 (34%), Gaps = 88/395 (22%)
Query: 479 SEVPRPPEPSQ--GPSTTSSGGGTGPHPPSG---TTLRPPTSSTPGGPPGAENSTSHQPA 533
S+VP+ P SQ S G T P S +T PPT S +S S QP
Sbjct: 43 SDVPQGPSDSQILQGLCASEGPSTSVLPTSAEGPSTFVPPTISEA-------SSASGQPT 95
Query: 534 TPGGDTAQTPKPGTSQPMPPGVGTSTSHQPATPSGGTAQTPEPGTSQPMPPSMGTSTSHQ 593
G PGTS P G STS P T S G + S+ S ++S +
Sbjct: 96 ISEG-------PGTSVLPTPSEGLSTSGPP-TISKGLCTSVTLAASEGRNTSRPPTSSEE 147
Query: 594 PATPGGGTAQTPEAGTSQPMPPGMGTSTSHQPTT---PGGGTAQTPEPGTSQPMPLSKST 650
P+T TA + TS P PG GTSTS PT P TP+ G P +
Sbjct: 148 PSTSVPPTASEVPS-TSLPPTPGEGTSTSVPPTAYEGPSTSVVPTPDEG-----PSTSVL 201
Query: 651 PSSGGGPSEDKRFSVVDMAALGGVLGALLLLALLGLAVLVHKHYGPRLKCCSGKAPEPQP 710
P+ G GP + V +AA G L +V GP S P
Sbjct: 202 PTPGEGPG-----TSVPLAATEG----------LSTSVQATPDEGP-----STSVPPTAT 241
Query: 711 QGFDNQAFLPDHKANWAPVPSPTHDPKPAEAPMPAEPAPPG--------PASPGGAPEPP 762
+G PVP PT D E P + PA PG PA+ G
Sbjct: 242 EGLS------------TPVP-PTRD----EGPSTSVPATPGEGPSTSVLPAASDGQSISL 284
Query: 763 AAARAGGS-----PTAVRSILTKERRPEGGYKAVWFGEDIG---------TEADVVVLNA 808
R GS PTA + T + G + G T + + +
Sbjct: 285 VPTRGKGSSTSVPPTATEGLSTSVQPTAGEGSSTSVPPTPGGGLSTSVPPTATEELSTSV 344
Query: 809 PTLDVDGASDSGSGDEGEGAGRGGGPYDAPGGDDS 843
P +G S S GEG P + G D S
Sbjct: 345 PPTPGEGPSTSVLPIPGEGLSTSVPPTASDGSDTS 379
>gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens]
Length = 4588
Score = 84.0 bits (206), Expect = 5e-16
Identities = 83/326 (25%), Positives = 135/326 (41%), Gaps = 30/326 (9%)
Query: 85 DYEEKSLLEAQLLCQSGGTLVTQLRVFVSVLDVNDNAPEFPFKTKEIRVEEDTKVNSTVI 144
D E+KS + G T + +VF+ V+D ND+ P+F E+ + EDT + ++
Sbjct: 1418 DAEQKSNYNLTVEATDGTTTILT-QVFIKVIDTNDHRPQFSTSKYEVVIPEDTAPETEIL 1476
Query: 145 PETQLQAEDRDKDDILFYTLQEMTAGASDYFSLVSVNRPALRLDRPLDFYERPNMTFWLL 204
Q+ A D+D+ + L YTLQ S + +L LD T ++
Sbjct: 1477 ---QISAVDQDEKNKLIYTLQSSRDPLSLKKFRLDPATGSLYTSEKLDHEAVHQHTLTVM 1533
Query: 205 VRDTPGENVEPSHTATATLVLNVVPADLRPPWFLPCTFSDGYVCIQAQYHGAVPTGHILP 264
VRD P A +V+NV + PWF + Y G V +
Sbjct: 1534 VRDQD----VPVKRNFARIVVNVSDTNDHAPWF-----------TASSYKGRVYESAAVG 1578
Query: 265 SPLVLRPGPIYAEDGDRGINQPIIYSIFRGNVNGTFIIHPDSGNLTVARSV--PSPMTFL 322
S ++ + A D D+G N ++YSI GN+ +F+I P G++ A+ + + +
Sbjct: 1579 SVVL----QVTALDKDKGKNAEVLYSIESGNIGNSFMIDPVLGSIKTAKELDRSNQAEYD 1634
Query: 323 LLVKGQQADLARYS-VTQVTVEAVAAAGSPPRFPQRLYRGTVARGAGAGVVVKDAAAPSQ 381
L+VK S +T V + A + P+F + Y ++ G V A SQ
Sbjct: 1635 LMVKATDKGSPPMSEITSVRIFVTIADNASPKFTSKEYSVELSETVSIGSFVGMVTAHSQ 1694
Query: 382 PLRIQAQDPEFSDLNSAITYRITNHS 407
+ E D N+ + I HS
Sbjct: 1695 SSVVY----EIKDGNTGDAFDINPHS 1716
Score = 77.0 bits (188), Expect = 7e-14
Identities = 105/419 (25%), Positives = 171/419 (40%), Gaps = 51/419 (12%)
Query: 51 DIHVPEGQEVT---LGALSTPFAFRIQGNQLFLNVTPDYEEKSLLEAQLLCQSGGTLVTQ 107
D + E+T LG+ + F +L + D EE+++ + GG Q
Sbjct: 3049 DADIRSNAEITYTLLGSGAEKFKLNPDTGELKTSTPLDREEQAVYHLLVRATDGGGRFCQ 3108
Query: 108 LRVFVSVLDVNDNAPEFPFKTKEIRVEEDTKVNSTVIPETQLQAEDRDK--DDILFYTLQ 165
+ +++ DVNDNAPEF I V E+T+ + + T++QA D D + + Y+L
Sbjct: 3109 ASIVLTLEDVNDNAPEFSADPYAITVFENTEPGTLL---TRVQATDADAGLNRKILYSLI 3165
Query: 166 EMTAGASDYFSLVSVNRPALRLDRPLDFYERPNMTFWLLVRDTPGENVEPSHTATATLVL 225
+ G L + ++L++PLD R + L + + TAT T+++
Sbjct: 3166 DSADGQFSINELSGI----IQLEKPLD---RELQAVYTLSLKAVDQGLPRRLTATGTVIV 3218
Query: 226 NVVPADLRPPWFLPCTFSDGYVCIQAQYHGAVPTGHILPSPLVLRPGPIYAEDGDRGINQ 285
+V+ + PP F + + +GA + IL VL+ +YA D N
Sbjct: 3219 SVLDINDNPPVF------------EYREYGATVSEDILVGTEVLQ---VYAASRDIEANA 3263
Query: 286 PIIYSIFRGNVNGTFIIHPDSGNLTVARSV--PSPMTFLLLVKGQQADLARYS-VTQVTV 342
I YSI GN +G F I +G + + ++ S + L V+ S V V V
Sbjct: 3264 EITYSIISGNEHGKFSIDSKTGAVFIIENLDYESSHEYYLTVEATDGGTPSLSDVATVNV 3323
Query: 343 EAVAAAGSPPRFPQRLYRGTVARGAGAGVVVKDAAAPSQPLRIQAQDPEFSDLNSAITYR 402
+ P F Q Y V+ +DA + + A D + NS I Y
Sbjct: 3324 NVTDINDNTPVFSQDTY---------TTVISEDAVLEQSVITVMADDAD-GPSNSHIHYS 3373
Query: 403 I---TNHSHFRME---GEVVLTTTTLAQAGAFYA-EVEA-HNTVTSGTATTVIEIQVSE 453
I S F ++ GEV +T + + Y V+A N TT + I VS+
Sbjct: 3374 IIDGNQGSSFTIDPVRGEVKVTKLLDRETISGYTLTVQASDNGSPPRVNTTTVNIDVSD 3432
Score = 60.8 bits (146), Expect = 5e-09
Identities = 70/279 (25%), Positives = 120/279 (43%), Gaps = 30/279 (10%)
Query: 112 VSVLDVNDNAPEFPFKTKEIRVEEDTKVNSTVIPETQLQAEDRDKDDILFYTLQEMTAGA 171
V V+D NDN PEF ++ + V ED +V+S +I Q++A D+D T +T
Sbjct: 810 VVVVDANDNPPEFLQESYFVEVSEDKEVHSEII---QVEATDKDLGPNGHVTYSIVT--D 864
Query: 172 SDYFSLVSVNRPALRLDRPLDFYERPNMTFWLLVRDTPGENVEPSHTATATLVLNVVPAD 231
+D FS+ SV + + RPLD + + + RD E EP +T + +++ +
Sbjct: 865 TDTFSIDSVT-GVVNIARPLDRELQHEHSLKIEARDQARE--EPQLFSTVVVKVSLEDVN 921
Query: 232 LRPPWFLPCTFSDGYVCIQAQYHGAVPTGHILPSPLVLRPGPIYAEDGDRGINQPIIYSI 291
PP F+P + + + +P G ++ + A D D G + + YS+
Sbjct: 922 DNPPTFIPPNY-------RVKVREDLPEGTVIMW--------LEAHDPDLGQSGQVRYSL 966
Query: 292 FRGNVNGTFIIHPDSGNLTVARSVPSP------MTFLLLVKGQQADLARYSVTQVTVEAV 345
+ G F + SG + + + + +T KG+ L+ +V V V
Sbjct: 967 L-DHGEGNFDVDKLSGAVRIVQQLDFEKKQVYNLTVRAKDKGKPVSLSSTCYVEVEVVDV 1025
Query: 346 AAAGSPPRFPQRLYRGTVARGAGAGVVVKDAAAPSQPLR 384
PP F + +GTV A G +V +A + R
Sbjct: 1026 NENLHPPVFSSFVEKGTVKEDAPVGSLVMTVSAHDEDAR 1064
Score = 59.3 bits (142), Expect = 1e-08
Identities = 83/362 (22%), Positives = 132/362 (36%), Gaps = 43/362 (11%)
Query: 104 LVTQLRVFVSVLDVNDNAPEFPFKTKEIRVEEDTKVNSTVIPETQ----LQAEDRDKDDI 159
L T V V + D NDNAP F + E +NS V+ + ++A D DKD
Sbjct: 1745 LSTNTTVLVHLQDENDNAPVFMQAEYTGLISESASINSVVLTDRNVPLVIRAADADKDSN 1804
Query: 160 LFYTLQEMTAGASDYFSLVSVNRPALRLDRPLDFYERPNMTFWLLVRDTPGENVEPSHTA 219
+ YF++ S + A+ LD+ E F + V D + + A
Sbjct: 1805 ALLVYHIVEPSVHTYFAIDS-STGAIHTVLSLDYEETSIFHFTVQVHDMGTPRLFAEYAA 1863
Query: 220 TATLVLNVVPADLRPPWFLPCTFSDGYVCIQAQYHGAVPTGHILPSPLVLRPGPIYAEDG 279
T+ +V+ + PP F + Y ++ +LP+ ++ + A D
Sbjct: 1864 NVTV--HVIDINDCPPVFA-----------KPLYEASL----LLPTYKGVKVITVNATDA 1906
Query: 280 DRGINQPIIYSIFRGNVNGTFIIHPDSGNLTVARSVPSPMTFLLLVKGQQADLARYSVTQ 339
D +IYSI GN+ F + +G LTV + + L V+ A +T
Sbjct: 1907 DSSAFSQLIYSITEGNIGEKFSMDYKTGALTVQNTTQLRSRYELTVRASDGRFA--GLTS 1964
Query: 340 VTVEAVAAAGSPPRFPQRLYRGTVARGAGAGVVVKDAAAPSQPLRIQAQDPEFSDLNSAI 399
V + + S +F Q +Y V + + A P +N +
Sbjct: 1965 VKINVKESKESHLKFTQDVYSAVVKENSTEAETLAVITAIGNP------------INEPL 2012
Query: 400 TYRITNHSH----FRMEGEVVLTTTTL--AQAGAFYAEVE-AHNTVTSGTATTVIEIQVS 452
Y I N R G + T T Q AF VE S A V+++ V
Sbjct: 2013 FYHILNPDRRFKISRTSGVLSTTGTPFDREQQEAFDVVVEVTEEHKPSAVAHVVVKVIVE 2072
Query: 453 EQ 454
+Q
Sbjct: 2073 DQ 2074
Score = 58.9 bits (141), Expect = 2e-08
Identities = 79/339 (23%), Positives = 131/339 (38%), Gaps = 39/339 (11%)
Query: 109 RVFVSVLDVNDNAPEFPFKTKEIRVEEDTKVNSTVIPETQLQAEDRDKDDILFYTLQEMT 168
R+ V+V D ND+AP F + + RV E V S V+ T L +D+ K+ + Y+++
Sbjct: 1547 RIVVNVSDTNDHAPWFTASSYKGRVYESAAVGSVVLQVTALD-KDKGKNAEVLYSIESGN 1605
Query: 169 AGASDYFSLVSVNRPALRLDRPLDFYERPNMTFWLLVRDTPGENVEPSHTATATLVLNVV 228
G S P L + +R N + L+ + P T+ + V
Sbjct: 1606 IGNSFMID------PVLGSIKTAKELDRSNQAEYDLMVKATDKGSPPMSEITSVRIF-VT 1658
Query: 229 PADLRPPWFLPCTFSDGYVCIQAQYHGAVPTGHILPSPLVLRPGPIYAEDGDRGINQPII 288
AD P F +S + V G + G + A ++
Sbjct: 1659 IADNASPKFTSKEYS-------VELSETVSIGSFV--------GMVTAHS-----QSSVV 1698
Query: 289 YSIFRGNVNGTFIIHPDSGNLTVARSVPSPMTFLLLVKGQQADLARYSV-TQVTVEAVAA 347
Y I GN F I+P SG + +++ + + Q ++A S T V V
Sbjct: 1699 YEIKDGNTGDAFDINPHSGTIITQKALDFETLPIYTLIIQGTNMAGLSTNTTVLVHLQDE 1758
Query: 348 AGSPPRFPQRLYRGTVARGAGAGVVVKDAAAPSQPLRIQAQDPEFSDLNSAITYRITN-- 405
+ P F Q Y G ++ A VV + PL I+A D + D N+ + Y I
Sbjct: 1759 NDNAPVFMQAEYTGLISESASINSVV--LTDRNVPLVIRAADAD-KDSNALLVYHIVEPS 1815
Query: 406 -HSHFRMEGEVVLTTTTLA----QAGAFYAEVEAHNTVT 439
H++F ++ T L+ + F+ V+ H+ T
Sbjct: 1816 VHTYFAIDSSTGAIHTVLSLDYEETSIFHFTVQVHDMGT 1854
Score = 56.2 bits (134), Expect = 1e-07
Identities = 85/377 (22%), Positives = 155/377 (41%), Gaps = 42/377 (11%)
Query: 38 EVEENTNVTEPLVDIHV--PEGQEVTLGALS-TPFA-FRIQGNQLFLNVTPDYEEKSLLE 93
E+ E+ V P+V + PEG +V PF+ F I N +NV + ++
Sbjct: 2190 EIAESIQVHSPVVHVQANSPEGLKVFYSITDGDPFSQFTINFNTGVINVIAPLDFEAHPA 2249
Query: 94 AQLLCQSGGTLV-TQLRVFVSVL--DVNDNAPEFPFKTKEIRVEEDTKVNSTVIPETQLQ 150
+L ++ +L VFV ++ D+NDN P F ++ + + E + + ++V+ Q++
Sbjct: 2250 YKLSIRATDSLTGAHAEVFVDIIVDDINDNPPVFAQQSYAVTLSEASVIGTSVV---QVR 2306
Query: 151 AEDRDKDDI--LFYTLQEMTAGASDYFSLVSVNRPALRLDRPLDFYERPNMTFWLLVRDT 208
A D D + + Y + + + D+F V + + L R LD+ + T + VR
Sbjct: 2307 ATDSDSEPNRGISYQMFGNHSKSHDHFH-VDSSTGLISLLRTLDYEQSRQHT--IFVRAV 2363
Query: 209 PGENVEPSHTATATLVLNVVPADLRPPWFLPCTFSDGYVCIQAQYHGAVPTGHILPSPLV 268
G P+ ++ + ++V + PP F + +A+ P GH +
Sbjct: 2364 DGG--MPTLSSDVIVTVDVTDLNDNPPLFEQQIY-------EARISEHAPHGHFVTC--- 2411
Query: 269 LRPGPIYAEDGDRGINQPIIYSIFRGNVNGTFIIHPDSGNLTVARSVPSPMTFLLLVKGQ 328
+ A D D + YSI GN + F+I +G +T++ + +
Sbjct: 2412 -----VKAYDADSSDIDKLQYSILSGNDHKHFVIDSATGIITLSNLHRHALKPFYSLNLS 2466
Query: 329 QADLARYSVTQVTVEAVAAAGSPPRFPQRLYRGTVARGAGAGVVVKDAAAPSQPLRIQAQ 388
+D S TQV V + P F Q Y +A A +V + ++
Sbjct: 2467 VSDGVFRSSTQVHVTVIGGNLHSPAFLQNEYEVELAENAPLHTLV---------MEVKTT 2517
Query: 389 DPEFSDLNSAITYRITN 405
D + S + +TY I N
Sbjct: 2518 DGD-SGIYGHVTYHIVN 2533
Score = 51.6 bits (122), Expect = 3e-06
Identities = 90/402 (22%), Positives = 158/402 (39%), Gaps = 50/402 (12%)
Query: 38 EVEENTNVTEPLVDIHV------PEGQEVTLGALSTPFAFRIQGNQLFLNVTP------D 85
EV E+ V ++ + P G VT ++ F I +N+
Sbjct: 830 EVSEDKEVHSEIIQVEATDKDLGPNGH-VTYSIVTDTDTFSIDSVTGVVNIARPLDRELQ 888
Query: 86 YEEKSLLEAQLLCQSGGTLVTQLRVFVSVLDVNDNAPEFPFKTKEIRVEEDTKVNSTVIP 145
+E +EA+ + L + + V VS+ DVNDN P F ++V ED TVI
Sbjct: 889 HEHSLKIEARDQAREEPQLFSTVVVKVSLEDVNDNPPTFIPPNYRVKVREDLP-EGTVIM 947
Query: 146 ETQLQAEDRDKDDILFYTLQEMTAGASDYFSLVSVNRPALRLDRPLDFYERPNMTFWLLV 205
+ D + + Y+L + G D L A+R+ + LDF ++ +
Sbjct: 948 WLEAHDPDLGQSGQVRYSLLDHGEGNFDVDKLSG----AVRIVQQLDFEKKQVYNLTVRA 1003
Query: 206 RDTPGENVEPSHTATATLVLNVVPADLRPPWFLPCTFSDGYVCIQAQYHGAVPTGHILPS 265
+D G+ V S T + + V +L PP F +F + + P G ++ +
Sbjct: 1004 KD-KGKPVSLSSTCYVEVEVVDVNENLHPPVF--SSFVE-----KGTVKEDAPVGSLVMT 1055
Query: 266 PLVLRPGPIYAEDGDRGINQPIIYSIFRGNVNGTFIIHPDSGNLTVARSVPSPMT---FL 322
+ A D D + I YSI G+ G F I ++G + + + T +L
Sbjct: 1056 --------VSAHDEDARRDGEIRYSIRDGSGVGVFKIGEETGVIETSDRLDRESTSHYWL 1107
Query: 323 LLVKGQQADLARYSVTQVTVEAVAAAGSPPRFPQRLYRGTVARGAGAGVVVKDAAAPSQP 382
+ Q + S ++ +E + P+ + +Y + + V V
Sbjct: 1108 TVFATDQGVVPLSSFIEIYIEVEDVNDNAPQTSEPVYYPEIMENSPKDVSV--------- 1158
Query: 383 LRIQAQDPEFSDLNSAITYRITN---HSHFRMEGEVVLTTTT 421
++I+A DP+ S N + Y+IT+ F + + L TTT
Sbjct: 1159 VQIEAFDPD-SSSNDKLMYKITSGNPQGFFSIHPKTGLITTT 1199
Score = 50.1 bits (118), Expect = 9e-06
Identities = 53/211 (25%), Positives = 87/211 (41%), Gaps = 25/211 (11%)
Query: 108 LRVFVSVLDVNDNAPEFPFKTKEIRVEEDTKVNSTVIPETQLQAEDRDK--DDILFYTLQ 165
+ +++ V DVNDNAP+ + E++ + +V+ Q++A D D +D L Y +
Sbjct: 1123 IEIYIEVEDVNDNAPQTSEPVYYPEIMENSPKDVSVV---QIEAFDPDSSSNDKLMYKIT 1179
Query: 166 EMTAGASDYFSLVSVNRPALRLDRPLDFYERPNMTFWLLVRDTPGENVEPSHTATATLVL 225
+ +FS+ R LD ++ + V D N P + A +++
Sbjct: 1180 --SGNPQGFFSIHPKTGLITTTSRKLDREQQDEHILEVTVTD----NGSPPKSTIARVIV 1233
Query: 226 NVVPADLRPPWFLPCTFSDGYVCIQAQYHGAVPTGHILPSPLVLRPGPIY---AEDGDRG 282
++ + P FL Q Y +P R P+Y A D D G
Sbjct: 1234 KILDENDNKPQFL-----------QKFYKIRLPEREKPDRERNARREPLYHVIATDKDEG 1282
Query: 283 INQPIIYSIFRGNVNGTFIIHPDSGNLTVAR 313
N I YSI GN +G F I P +G ++ R
Sbjct: 1283 PNAEISYSIEDGNEHGKFFIEPKTGVVSSKR 1313
Score = 47.4 bits (111), Expect = 6e-05
Identities = 64/324 (19%), Positives = 127/324 (39%), Gaps = 45/324 (13%)
Query: 89 KSLLEAQLLCQSGGTLVTQLRVFVSVLDVNDNAPEFPFKTKEIRVEEDTKVNSTVIPETQ 148
+ ++ +L+ + G V V V + D NDNAP+F E+ + ++V+
Sbjct: 2561 EKVISVRLMAKDAGGKVAFCTVNVILTDDNDNAPQFRATKYEVNIGSSAAKGTSVVKVLA 2620
Query: 149 LQAEDRDKDDILFYTLQEMTAGASDYFSLVSVNRPALRLDRPLDFYERPNMTFWLLVRDT 208
A++ DI + + A + + +N+ + + N F VR
Sbjct: 2621 SDADEGSNADITY----AIEADSESVKENLEINKLSGVITTKESLIGLENEFFTFFVRAV 2676
Query: 209 PGENVEPSHTATATLVLNVVPADLRPPWFLPCTFSDGYVCIQAQYHGAVPTGHILPSPLV 268
+N PS + + + ++P +++ P FS+ + VP G +
Sbjct: 2677 --DNGSPSKESVVLVYVKILPPEMQLP-----KFSEPFYTFTVSED--VPIGTEIDL--- 2724
Query: 269 LRPGPIYAEDGDRGINQPIIYSIFRGNV-----NGTFIIHPDSGNLTVARSVPSPMT--- 320
I AE + ++YS+ +GN + +F+I SG L + +S+ T
Sbjct: 2725 -----IRAEH-----SGTVLYSLVKGNTPESNRDESFVIDRQSGRLKLEKSLDHETTKWY 2774
Query: 321 -FLLLVKGQQADLARYSVTQVTVEAVAAAGSPPRFPQRLYRGTVARGAGAGVVVKDAAAP 379
F +L + Q D + V+++ A + P F Y +V++
Sbjct: 2775 QFSILARCTQDDHEMVASVDVSIQVKDANDNSPVFESSPYE---------AFIVENLPGG 2825
Query: 380 SQPLRIQAQDPEFSDLNSAITYRI 403
S+ ++I+A D + S N + Y +
Sbjct: 2826 SRVIQIRASDAD-SGTNGQVMYSL 2848
Score = 46.2 bits (108), Expect = 1e-04
Identities = 75/365 (20%), Positives = 134/365 (36%), Gaps = 41/365 (11%)
Query: 35 DIFEVEENTNVTEPLVDIHVPEGQEVTLGALSTPFAFRIQGNQLFLNVTPDYEEKSLLEA 94
D+ E + V LV + PE F Q +L L + D+E +
Sbjct: 2723 DLIRAEHSGTVLYSLVKGNTPESNR------DESFVIDRQSGRLKLEKSLDHETTKWYQF 2776
Query: 95 QLLC---QSGGTLVTQLRVFVSVLDVNDNAPEFPFKTKEIRVEEDTKVNSTVIPETQLQA 151
+L Q +V + V + V D NDN+P F E + E+ S VI A
Sbjct: 2777 SILARCTQDDHEMVASVDVSIQVKDANDNSPVFESSPYEAFIVENLPGGSRVIQIRASDA 2836
Query: 152 EDRDKDDILFYTLQEMTAGASDYFSLVSVNRPALRLDRPLDFYERPNMTFWLLVRDTPGE 211
+ +++ Q + + F+ +++ + + LD +R N ++ D GE
Sbjct: 2837 DSGTNGQVMYSLDQSQSVEVIESFA-INMETGWITTLKELDHEKRDNYQIKVVASD-HGE 2894
Query: 212 NVEPSHTATATLVLNVVPADLRPPWFLPCTFSDGYVCIQAQYHGAV----PTGHILPSPL 267
++ S +TA + + V + PP F Y G V P G ++
Sbjct: 2895 KIQLS--STAIVDVTVTDVNDSPPRF-----------TAEIYKGTVSEDDPQGGVI---A 2938
Query: 268 VLRPGPIYAEDGDRGINQPIIYSIFRGNVNGTFIIHPDSGNLTVARSVPSPM----TFLL 323
+L +E+ IN+ + Y I G+ G F + V P +LL
Sbjct: 2939 ILSTTDADSEE----INRQVTYFITGGDPLGQFAVETIQNEWKVYVKKPLDREKRDNYLL 2994
Query: 324 LVKGQQADLARYSVTQVTVEAVAAAGSPPRFPQRLYRGTVARGAGAGVVVKDAAAPSQPL 383
+ + ++ +V V + A + P + LY T+ G ++ +A +
Sbjct: 2995 TITATDGTFSSKAIVEVKV--LDANDNSPVCEKTLYSDTIPEDVLPGKLIMQISATDADI 3052
Query: 384 RIQAQ 388
R A+
Sbjct: 3053 RSNAE 3057
Score = 38.5 bits (88), Expect = 0.026
Identities = 75/324 (23%), Positives = 128/324 (39%), Gaps = 51/324 (15%)
Query: 112 VSVLDVNDNAPEFPFKTKEIRVEEDTKVNSTVIPETQLQAEDRDKDDILFYTLQEMTAGA 171
+++ ++NDN P F E + D V + T + A D D+ ++ Y ++
Sbjct: 557 ITLNNLNDNTPLFEKINCEGTIPRDLGVGEQI---TTVSAIDADELQLVQYQIE--AGNE 611
Query: 172 SDYFSLVSVNRPALRLDRPLDFYERPNMTFWLL-VRDTPGEN----------VEPSH--- 217
D+FSL + N L L R L ++F L + T GEN V SH
Sbjct: 612 LDFFSL-NPNSGVLSLKRSLMDGLGAKVSFHSLRITATDGENFATPLYINITVAASHKLV 670
Query: 218 ------TATATLVLNVV--PADLRPPWFLPCTFSDGYVCIQA---QYHGAVPTGHILPSP 266
T A ++ + L + F D + + A Q+ +PTG +
Sbjct: 671 NLQCEETGVAKMLAEKLLQANKLHNQGEVEDIFFDSH-SVNAHIPQFRSTLPTGIQVKEN 729
Query: 267 LVLRPGPIY--AEDGDRGINQPIIYSIFRGNVNGTFIIHPDSGNLTVARSVPSPMTFLLL 324
+ I+ + D D G N ++Y++ GN + F+I ++G L + + T
Sbjct: 730 QPVGSSVIFMNSTDLDTGFNGKLVYAVSGGNEDSCFMIDMETGMLKILSPLDRETTDKYT 789
Query: 325 VKGQQADL-----ARYSVTQVTVEAVAAAGSPPRFPQRLYRGTVARGAGAGVVVKDAAAP 379
+ DL A + + V V V A +PP F Q Y V+ +D
Sbjct: 790 LNITVYDLGIPQKAAWRLLHVVV--VDANDNPPEFLQESYFVEVS---------EDKEVH 838
Query: 380 SQPLRIQAQDPEFSDLNSAITYRI 403
S+ ++++A D + N +TY I
Sbjct: 839 SEIIQVEATDKDLGP-NGHVTYSI 861
Score = 38.1 bits (87), Expect = 0.034
Identities = 59/313 (18%), Positives = 120/313 (38%), Gaps = 40/313 (12%)
Query: 85 DYEEKSLLEAQLLCQSGGTLVTQLRVFVSVLDVNDNAPEFPFKTKEIRVEE----DTKVN 140
+ +++ +LE + T RV V +LD NDN P+F K +IR+ E D + N
Sbjct: 1206 EQQDEHILEVTVTDNGSPPKSTIARVIVKILDENDNKPQFLQKFYKIRLPEREKPDRERN 1265
Query: 141 STVIPETQLQAEDRDK--DDILFYTLQEMTAGASDYFSLVSVNRPALRLDRPLDFYERPN 198
+ P + A D+D+ + + Y++++ + + + R ++
Sbjct: 1266 ARREPLYHVIATDKDEGPNAEISYSIEDGNEHGKFFIEPKTGVVSSKRFSAAGEYD---- 1321
Query: 199 MTFWLLVRDTPGENVEPSHTATATLVLNVVPADLRPPWFLPCTFSDGYVCIQAQYHGAVP 258
++ +N P ++T L + + P P +F + + + P
Sbjct: 1322 -----ILSIKAVDNGRPQKSSTTRLHIEWISKP--KPSLEPISFEESFFTFTVM--ESDP 1372
Query: 259 TGHILPSPLVLRPGPIYAEDGDRGINQPIIYSIFRGNVNGTFIIHPDSGNLTVARSVPSP 318
H++ V PG P+ + I GN + F + +G + VA+ + +
Sbjct: 1373 VAHMIGVISVEPPG------------IPLWFDITGGNYDSHFDVDKGTGTIIVAKPLDAE 1420
Query: 319 MTFLLLVKGQQADLARYSVTQVTVEAVAAAGSPPRFPQRLYRGTVARGAGAGVVVKDAAA 378
+ + D +TQV ++ + P+F Y V+ +D A
Sbjct: 1421 QKSNYNLTVEATDGTTTILTQVFIKVIDTNDHRPQFSTSKYE---------VVIPEDTAP 1471
Query: 379 PSQPLRIQAQDPE 391
++ L+I A D +
Sbjct: 1472 ETEILQISAVDQD 1484
Score = 31.2 bits (69), Expect = 4.2
Identities = 53/247 (21%), Positives = 99/247 (40%), Gaps = 39/247 (15%)
Query: 22 GTMAQAQYCSVNKDIFEVEENTNV------TEPLVDIHVPEGQEVTL------GALSTPF 69
GT + + +VN ++ ++ +NT V T + + V E +T+ G ++
Sbjct: 3311 GTPSLSDVATVNVNVTDINDNTPVFSQDTYTTVISEDAVLEQSVITVMADDADGPSNSHI 3370
Query: 70 AFRI----QGNQLFLN-VTPDYEEKSLLEAQLLCQSGGTLVTQLR------------VFV 112
+ I QG+ ++ V + + LL+ + + SG TL Q V +
Sbjct: 3371 HYSIIDGNQGSSFTIDPVRGEVKVTKLLDRETI--SGYTLTVQASDNGSPPRVNTTTVNI 3428
Query: 113 SVLDVNDNAPEFPFKTKEIRVEEDTKVNSTVIPETQLQAEDRDKDDILFYTLQEMTAGAS 172
V DVNDNAP F + ++E+ V +V+ + F+T+ +T
Sbjct: 3429 DVSDVNDNAPVFSRGNYSVIIQENKPVGFSVLQLVVTDEDSSHNGPPFFFTI--VTGNDE 3486
Query: 173 DYFSLVSVNRPALRLDRPLDFYERPNMTFWLLVRDTPGENVEPSHTATATLVLNVVPADL 232
F VN + L +R +LL + +N +P ++ + + V+ +
Sbjct: 3487 KAF---EVNPQGVLLTS--SAIKRKEKDHYLL-QVKVADNGKPQLSSLTYIDIRVIEESI 3540
Query: 233 RPPWFLP 239
PP LP
Sbjct: 3541 YPPAILP 3547
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 83.6 bits (205), Expect = 7e-16
Identities = 89/346 (25%), Positives = 103/346 (29%), Gaps = 66/346 (19%)
Query: 452 SEQEPPSTDVPPSPEAGGTT-GPWTSTTSEVPRPPEPSQGPSTTSSGGGTGPHPPSGTTL 510
S + PP P P+ G GP P PP QGP GP PP
Sbjct: 110 SPRSPPGKPQGPPPQGGNQPQGP--------PPPPGKPQGPPPQGGNKPQGPPPPGKPQG 161
Query: 511 RPP--------TSSTPGGPPGAENSTSHQPATP-------------GGDTAQTPKPGTSQ 549
PP + S PG P G +QP P GG+ Q P P
Sbjct: 162 PPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP 221
Query: 550 PMPPGVGTSTSHQPATPSGGTAQTPEPGTSQPMPPSMGTSTSHQPATPGGGTAQTPEAGT 609
PP G + S +P G P G +QP P P GG Q P
Sbjct: 222 QGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG 281
Query: 610 SQPMPPGMGTSTSHQPTTPGGGTAQTPEPGTSQPMPLSKSTPSSGGGPSEDKRFSVVDMA 669
PP G S S +P G P G +QP G P +
Sbjct: 282 KPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ---------- 331
Query: 670 ALGGVLGALLLLALLGLAVLVHKHYGPRLKCCSGKAPEPQPQG--FDNQAFLPDHKANWA 727
GG +K GP GK P PQG A P K
Sbjct: 332 --GG-----------------NKPQGPP---PPGKPQGPPPQGGSKSRSARSPPGKPQGP 369
Query: 728 PVPSPTH--DPKPAEAPMPAEPAPPGPASPGGAPEPPAAARAGGSP 771
P + P P P +P P P G P PP R P
Sbjct: 370 PQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 415
Score = 80.5 bits (197), Expect = 6e-15
Identities = 95/362 (26%), Positives = 110/362 (30%), Gaps = 70/362 (19%)
Query: 454 QEPPSTDVPPSPEAGGTTGPWTSTTSEVPR-PPEPSQGPSTTSSGGGTGPHPPSGTTLRP 512
Q PP P P G S PR PP QGP GP PP G P
Sbjct: 90 QGPPPPGKPQGPPPQGDK-------SRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP 142
Query: 513 PTSS-----------TPGGPPGAENSTSHQPATPGGDTAQTPKPGTSQPMPPGVGTSTSH 561
P P GPP ++ S +P G P G +QP P
Sbjct: 143 PPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 202
Query: 562 QPATPSGGTAQTPEPGTSQPMPPSMGTSTSHQPATPGGGTAQTPEAGTSQPMPPGMGTST 621
P G Q P P PP G + S +P G P G +QP P
Sbjct: 203 GPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGK 262
Query: 622 SHQPTTPGGGTAQTPEPGTSQPMPLSKSTPSSGGGPSEDKRF---SVVDMAALGGVLGAL 678
P GG Q P P P P GG S R GG
Sbjct: 263 PQGPPPQGGNKPQGPPPPGKPQGP-----PPQGGSKSRSSRSPPGKPQGPPPQGG----- 312
Query: 679 LLLALLGLAVLVHKHYGPRLKCCSGKAPEPQPQGFDNQAFLPDHKANWAPVPSPTHDPKP 738
++ GP GK P PQG + P P P +
Sbjct: 313 ------------NQPQGPPPP--PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRS 358
Query: 739 AEAPMPAEPA---------PPGPASP-GGAPEPPAAARAG---GSPTAVRSILTKERRPE 785
A +P P +P P GP P GG P+ P A AG G P R P+
Sbjct: 359 ARSP-PGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPP----------RPPQ 407
Query: 786 GG 787
GG
Sbjct: 408 GG 409
Score = 79.7 bits (195), Expect = 1e-14
Identities = 88/336 (26%), Positives = 110/336 (32%), Gaps = 60/336 (17%)
Query: 451 VSEQEPPSTDVPPSPEAGGTTGPWTSTTSEVPRPPEPSQGPSTTSSGGGTGPHPPSGTTL 510
VS++E PS + +P+ G + P PP QGP GP PP G
Sbjct: 23 VSQEESPSL-IAGNPQGAPPQGG--NKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 79
Query: 511 RPPTS--STPGGPPGAENSTSHQPATPGGDTAQTPK--PGTSQPMPPGVGTSTSHQPATP 566
PP + P GPP Q P GD +++P+ PG Q PP G P P
Sbjct: 80 GPPPQGGNKPQGPPPPGKP---QGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPP 136
Query: 567 ---------SGGTAQTPEPGTSQPMPPSMGTSTSHQPATPGGGTAQTPEAGTSQPMPPGM 617
G Q P P PP G + S +P G P G +QP P
Sbjct: 137 GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPP 196
Query: 618 GTSTSHQPTTPGGGTAQ-TPEPGTSQPMP--------LSKSTPSSGGGPSEDKRFSVVDM 668
P GG Q P PG Q P ++S P GP
Sbjct: 197 PPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQ-------- 248
Query: 669 AALGGVLGALLLLALLGLAVLVHKHYGPRLKCCSGKAPEPQPQGFDNQAFLPDHKANWAP 728
GG ++ GP GK P PQG + P P
Sbjct: 249 ---GG-----------------NQPQGPPPP--PGKPQGPPPQGGNKPQGPPPPGKPQGP 286
Query: 729 VPSPTHDPKPAEAP--MPAEPAPPGPASPGGAPEPP 762
P + + +P P P P G P G P PP
Sbjct: 287 PPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPP 322
Score = 72.0 bits (175), Expect = 2e-12
Identities = 87/341 (25%), Positives = 102/341 (29%), Gaps = 68/341 (19%)
Query: 455 EPPSTDVPPSPEAGGTTGPWTSTTSEVPRPPEPSQGPSTTSSGGGTGPHPPSGTTLRPPT 514
E S + PS AG G ++ PP P P GG P P PP
Sbjct: 21 EDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGP------PPP 74
Query: 515 SSTPGGPPGAENSTSHQPATPGGDTAQTPKPGTSQPMPPGVGTSTSHQPATPSGGTAQTP 574
P GPP GG+ Q P P PP G S P +P G P
Sbjct: 75 PGKPQGPP-----------PQGGNKPQGPPPPGKPQGPPPQGDK-SRSPRSPPGKPQGPP 122
Query: 575 EPGTSQPMPPSMGTSTSHQPATPGGGTAQTPEAGTSQPMPPGMGTSTSHQPTTPGGGTAQ 634
G +QP P P GG Q P PP G + S +P G
Sbjct: 123 PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQG 182
Query: 635 TPEPGTSQPMPLSKSTPSSGGGPSEDKRFSVVDMAALGGVLGALLLLALLGLAVLVHKHY 694
P G +QP G P + GG +K
Sbjct: 183 PPPQGGNQPQGPPPPPGKPQGPPPQ------------GG-----------------NKPQ 213
Query: 695 GPRLKCCSGKAPEPQPQGFDNQAFLPDHKANWA-PVPSPTHDPKPAEAPMPAEPAPPGPA 753
GP P +PQG Q D+K+ A P P P P P PP P
Sbjct: 214 GP--------PPPGKPQGPPPQG---DNKSQSARSPPGKPQGPPPQGGNQPQGPPPP-PG 261
Query: 754 SPGGAPE--------PPAAARAGGSPTAVRSILTKERRPEG 786
P G P PP + G P S R P G
Sbjct: 262 KPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPG 302
Score = 39.3 bits (90), Expect = 0.015
Identities = 50/203 (24%), Positives = 59/203 (29%), Gaps = 44/203 (21%)
Query: 570 TAQTPEPGTSQPMPPSMGTSTSHQPATPGGGTAQTPEAGTSQPM-PPGMGTSTSHQPTTP 628
+AQ SQ PS+ GG Q P + +P PP G + P P
Sbjct: 15 SAQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPP 74
Query: 629 GGGTAQTPEPGTSQPMPLSKSTPSSGGGPSEDKRFSVVDMAALGGVLGALLLLALLGLAV 688
G P G ++P G P DK S
Sbjct: 75 PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRS------------------------ 110
Query: 689 LVHKHYGPRLKCCSGKAPEPQPQGFDNQAFLPDHKANWAPVPSPTHDPKPAEAPMPAEPA 748
PR GK P PQG NQ P P P KP P P +P
Sbjct: 111 -------PRSP--PGKPQGPPPQG-GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQ 160
Query: 749 PPGP---------ASPGGAPEPP 762
P P SP G P+ P
Sbjct: 161 GPPPQGDNKSRSSRSPPGKPQGP 183
>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
sapiens]
Length = 309
Score = 83.2 bits (204), Expect = 9e-16
Identities = 89/332 (26%), Positives = 110/332 (33%), Gaps = 74/332 (22%)
Query: 451 VSEQEPPSTDVPPSPEAGGTTGPWTSTTSEVPRPPEPSQGPSTTSSGGGTGPHPPSGTTL 510
VS++E PS + PE G + P PP +G GP P G
Sbjct: 23 VSQEESPSV-ISGKPEGRRPQGG--NQPQRTPPPPGKPEGRPPQGGNQSQGPPPRPGKPE 79
Query: 511 RPPTS--STPGGPPGAENSTSHQPATPGGDTAQTPKPGTSQPM-PPGVGTSTSHQPATPS 567
PP + GPP QP GG+ +Q P P +P PP G + S P
Sbjct: 80 GPPPQGGNQSQGPPPRPGKPEGQP-PQGGNQSQGPPPRPGKPEGPPPQGGNQSQGP---- 134
Query: 568 GGTAQTPEPGTSQPMPPSMGTSTSHQPATPGGGTAQTPEAGT-SQPMPPGMGTSTSHQPT 626
P PG + PP G + P PG P+ G SQ PP G P
Sbjct: 135 -----PPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEG--PP 187
Query: 627 TPGGGTAQTPEPGTSQPMPLSKSTPSSGGGPSEDKRFSVVDMAALGGVLGALLLLALLGL 686
GG +Q P P +P + P GG S+
Sbjct: 188 PQGGNQSQGPPPRPGKP----EGPPPQGGNQSQ--------------------------- 216
Query: 687 AVLVHKHYGPRLKCCSGKAPEPQPQGFDNQAFLPDHKANWAPVPSPTHDPKPAEAPMPAE 746
GP + GK P QG + P H P P P E P
Sbjct: 217 --------GPPPR--PGKPEGPPSQGGNKPQGPPPH-------PGKPQGPPPQEGNKPQR 259
Query: 747 PAPP----GPASPGGAPE---PPAAARAGGSP 771
P PP GP PGG P+ PP A + G P
Sbjct: 260 PPPPGRPQGPPPPGGNPQQPLPPPAGKPQGPP 291
Score = 66.2 bits (160), Expect = 1e-10
Identities = 67/234 (28%), Positives = 81/234 (34%), Gaps = 26/234 (11%)
Query: 452 SEQEPPSTDVP--PSPEAGGTT-GPWTSTTSEVPRPPE---PSQGPSTTSSGGGTGPHPP 505
S+ PP P P P+ G + GP +PP+ SQGP G GP P
Sbjct: 68 SQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPPRP-GKPEGPPPQ 126
Query: 506 SGTTLR--PPTSSTPGGPPG-AENSTSHQPATPGGDTAQTPKPGT-SQPMPPGVGTSTSH 561
G + PP P GPP N + P PG P+ G SQ PP G
Sbjct: 127 GGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGP 186
Query: 562 QPATPSGGTAQTPEPGTSQPMPPSMGTSTSHQPATPG--------GGT---AQTPEAGTS 610
P + P PG + PP G + P PG GG P G
Sbjct: 187 PPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKP 246
Query: 611 QPMPPGMGTSTSHQPTTPGGGTAQTPEPGTS--QPMPLSKSTPSSGGGPSEDKR 662
Q PP G P P G P PG + QP+P P P + R
Sbjct: 247 QGPPPQEGNKPQRPP--PPGRPQGPPPPGGNPQQPLPPPAGKPQGPPPPPQGGR 298
Score = 63.9 bits (154), Expect = 6e-10
Identities = 61/211 (28%), Positives = 76/211 (36%), Gaps = 29/211 (13%)
Query: 453 EQEPP---STDVPPSPEAGGTTGP----WTSTTSEVPRPPEPSQGPSTTSSGGGTGPHPP 505
E +PP + P P G GP + PRP +P +GP GP P
Sbjct: 100 EGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKP-EGPPPQGGNQSQGPPPR 158
Query: 506 SGTTLRPPT---SSTPGGPPGAENSTSHQPATPGGDTAQTPKPGTSQPM-PPGVGTSTSH 561
G PP + + G PP P GG+ +Q P P +P PP G + S
Sbjct: 159 PGKPEGPPPQGGNQSQGPPP--HPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQ 216
Query: 562 ----QPATPSGGTAQ--------TPEPGTSQPMPPSMGTSTSHQPATPGGGTAQTPEAGT 609
+P P G +Q P PG Q PP G +P PG P G
Sbjct: 217 GPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQ-RPPPPGRPQGPPPPGGN 275
Query: 610 -SQPMPPGMGTSTSHQPTTPGGGTAQTPEPG 639
QP+PP G P P GG P G
Sbjct: 276 PQQPLPPPAGKPQG-PPPPPQGGRPHRPPQG 305
Score = 55.8 bits (133), Expect = 2e-07
Identities = 54/182 (29%), Positives = 65/182 (35%), Gaps = 25/182 (13%)
Query: 452 SEQEPPSTDVP--PSPEAGGTT-GPWTSTTSEVPRPPE---PSQGPSTTSSGGGTGPHPP 505
S+ PP P P P+ G + GP PP+ SQGP G GP P
Sbjct: 131 SQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPP-HPGKPEGPPPQ 189
Query: 506 SGTTLR--PPTSSTPGGPPGAENSTSH----QPATPGGDTAQ--------TPKPGTSQPM 551
G + PP P GPP + S +P P G +Q P PG Q
Sbjct: 190 GGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGP 249
Query: 552 PPGVGTSTSHQPATPSGGTAQTPEPG--TSQPMPPSMGTSTSHQPATPGGGTAQTPEAGT 609
PP G P P G P PG QP+PP G P GG + P+
Sbjct: 250 PPQEGNKPQRPP--PPGRPQGPPPPGGNPQQPLPPPAGKPQGPPPPPQGGRPHRPPQGQP 307
Query: 610 SQ 611
Q
Sbjct: 308 PQ 309
>gi|218505787 protocadherin 15 isoform CD2-1 precursor [Homo
sapiens]
Length = 1790
Score = 80.5 bits (197), Expect = 6e-15
Identities = 91/349 (26%), Positives = 148/349 (42%), Gaps = 37/349 (10%)
Query: 78 LFLNVT--------PDYEEKSLLEAQLLCQSGGTLVTQLRVFVSVLDVNDNAPEFPFKTK 129
LFLN T P +++ Q + + GT++ V + V D NDN+P F ++
Sbjct: 99 LFLNSTGRVLDRDPPMNIHSIVVQVQCINKKVGTIIYH-EVRIVVRDRNDNSPTFKHESY 157
Query: 130 EIRVEEDTKVNSTVIPETQLQAEDRDKDD--------ILFYTLQEMTAGASDYFSLVSVN 181
V E T V +T+ D DD ++ Y + T+ +D F + +
Sbjct: 158 YATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYNPDDPTS--NDTFEIPLML 215
Query: 182 RPALRLDRPLDFYERPNMTFWLLVRDTPGENVEPSHTATATLVLNVVPADLRPPWFLPCT 241
+ L + L+ YE F ++ + +N+ T T TL ++V+ D P FLPC
Sbjct: 216 TGNIVLRKRLN-YEDKTRYFVIIQANDRAQNLNERRTTTTTLTVDVLDGDDLGPMFLPCV 274
Query: 242 F-SDGYVCIQAQYHGAVP---TGHILPSPLVLRPGPIYAEDGDRGINQP-----IIYSIF 292
+ C Y A+P T L +P+++ P PI A D DR I P I+YSI
Sbjct: 275 LVPNTRDCRPLTYQAAIPELRTPEEL-NPIIVTP-PIQAIDQDRNIQPPSDRPGILYSIL 332
Query: 293 RGNVNG---TFIIHPDSGNLTVARSVPSP--MTFLLLVKGQQAD-LARYSVTQVTVEAVA 346
G F +HP + L++ V F L++K +Q + + + +E +
Sbjct: 333 VGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHPLPAFAGLHIEILD 392
Query: 347 AAGSPPRFPQRLYRGTVARGAGAGVVVKDAAAPSQPLRIQAQDPEFSDL 395
P F Y+G + A G + D+ + PLRI A D + D+
Sbjct: 393 ENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIEDV 441
Score = 44.7 bits (104), Expect = 4e-04
Identities = 101/420 (24%), Positives = 157/420 (37%), Gaps = 73/420 (17%)
Query: 71 FRIQGN-QLFLNVTPDYEEKSLLEAQLLCQSGGTLV--TQLRVFVSVLDVNDNAPEFPFK 127
FRI N ++ V + E + E ++ G + L + + VLD++DN+P F
Sbjct: 775 FRITSNGSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNS 834
Query: 128 TKEIRVEEDTKVNSTVIPETQLQAEDRDKDDILFYTLQEMTAGASDYFSLVSVNRPALRL 187
T + VEE+ +T++ Q++A+D D + Y ++ +F + L L
Sbjct: 835 TYTVLVEENLPAGTTIL---QIEAKDVDLGANVSYRIRSPEV---KHFFALHPFTGELSL 888
Query: 188 DRPLDFYERP----NMTFWLLVRDTPGENVEPSHTATATLVLNVVPADLRPPWFLPCTFS 243
R LD+ P ++TF + D G P AT T++ V + PP F
Sbjct: 889 LRSLDYEAFPDQEASITFLVEAFDIYG--TMPPGIATVTVI--VKDMNDYPPVF------ 938
Query: 244 DGYVCIQAQYHGAVPTGHILPSPLVLRPGPIYAEDGD-------------RGINQPIIYS 290
+ Y G V + +P+ +YAED D + P S
Sbjct: 939 -----SKRIYKGMVAPDAVKGTPIT----TVYAEDADPPGLPASRVRYRVDDVQFPYPAS 989
Query: 291 IFRGNVNGTFIIHPDSGN-LTVARSVPSPMTFLLLVKGQQADLARYSVTQVTVE-AVAAA 348
IF + DSG +T P T LV D + TV+ V
Sbjct: 990 IFE--------VEEDSGRVITRVNLNEEPTTIFKLVVVAFDDGEPVMSSSATVKILVLHP 1041
Query: 349 GSPPRFPQRLYR-----GTVARGAGAGVVVKDAAAPSQPL---RIQAQDPEFSDLNSAIT 400
G PRF Q YR +G GV+ AAA +Q + + + + +N+
Sbjct: 1042 GEIPRFTQEEYRPPPVSELATKGTMVGVI--SAAAINQSIVYSIVSGNEEDTFGINN--- 1096
Query: 401 YRITNHSHFRMEGEVVLTTTTLAQAGAFYAEVEAHN---TVTSGTATTVIEIQVSEQEPP 457
IT + + T+ + + A EV N S TA IEIQ PP
Sbjct: 1097 --ITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPP 1154
Score = 39.7 bits (91), Expect = 0.012
Identities = 63/327 (19%), Positives = 128/327 (39%), Gaps = 38/327 (11%)
Query: 85 DYEEKSLLEAQLLCQSGGTLVTQLRVFVSVLDVNDNAPEFPFKTKEIRVEEDTKVNSTVI 144
D EE+ + G + V + V+D NDN P FP + ++ V D + +VI
Sbjct: 482 DREEQQTYTFSITAFDGVQESEPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVI 541
Query: 145 PETQLQAEDRDKDDILFYTLQEMTAGASDYFSLVSVNRPALRLDRPLDFYERPNMTFWLL 204
T + A++ +I + E+ GA F +++ + + ++ T+ L
Sbjct: 542 QLTAVDADEGSNGEITY----EILVGAQGDF-IINKTTGLITIAPGVEMI--VGRTYALT 594
Query: 205 VRDTPGENVEPSHTATATLVLNVVPADLR-PPWFLPCTFSDGYVCIQAQYHGAVPTGHIL 263
V+ + T+ + V+P + + PP F +S + A+ G +L
Sbjct: 595 VQAADNAPPAERRNSICTVYIEVLPPNNQSPPRFPQLMYS-------LEISEAMRVGAVL 647
Query: 264 PSPLVLRPGPIYAEDGDRGINQPIIYSIFRGNVNGTFIIHPDSGNLTVARSVPSPMT--F 321
+ + A D + I Y+I G+ F + +G LT+ +++ T +
Sbjct: 648 LN--------LQATDRE---GDSITYAIENGDPQRVFNLSETTGILTLGKALDRESTDRY 696
Query: 322 LLLVKGQQADLARYSVTQVTVEAVAAAGSPPRFPQRLYRGTVARGAGAGVVVKDAAAPSQ 381
+L++ S V + + P F L R + V + A +
Sbjct: 697 ILIITASDGRPDGTSTATVNIVVTDVNDNAPVFDPYLPR---------NLSVVEEEANAF 747
Query: 382 PLRIQAQDPEFSDLNSAITYRITNHSH 408
+++A DP+ + +N + Y + N ++
Sbjct: 748 VGQVKATDPD-AGINGQVHYSLGNFNN 773
>gi|115387123 protocadherin 15 isoform CD1-4 precursor [Homo
sapiens]
Length = 1955
Score = 80.1 bits (196), Expect = 8e-15
Identities = 91/348 (26%), Positives = 147/348 (42%), Gaps = 37/348 (10%)
Query: 78 LFLNVT--------PDYEEKSLLEAQLLCQSGGTLVTQLRVFVSVLDVNDNAPEFPFKTK 129
LFLN T P +++ Q + + GT++ V + V D NDN+P F ++
Sbjct: 94 LFLNSTGRVLDRDPPMNIHSIVVQVQCINKKVGTIIYH-EVRIVVRDRNDNSPTFKHESY 152
Query: 130 EIRVEEDTKVNSTVIPETQLQAEDRDKDD--------ILFYTLQEMTAGASDYFSLVSVN 181
V E T V +T+ D DD ++ Y + T+ +D F + +
Sbjct: 153 YATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYNPDDPTS--NDTFEIPLML 210
Query: 182 RPALRLDRPLDFYERPNMTFWLLVRDTPGENVEPSHTATATLVLNVVPADLRPPWFLPCT 241
+ L + L+ YE F ++ + +N+ T T TL ++V+ D P FLPC
Sbjct: 211 TGNIVLRKRLN-YEDKTRYFVIIQANDRAQNLNERRTTTTTLTVDVLDGDDLGPMFLPCV 269
Query: 242 F-SDGYVCIQAQYHGAVP---TGHILPSPLVLRPGPIYAEDGDRGINQP-----IIYSIF 292
+ C Y A+P T L +P+++ P PI A D DR I P I+YSI
Sbjct: 270 LVPNTRDCRPLTYQAAIPELRTPEEL-NPIIVTP-PIQAIDQDRNIQPPSDRPGILYSIL 327
Query: 293 RGNVNG---TFIIHPDSGNLTVARSVPSP--MTFLLLVKGQQAD-LARYSVTQVTVEAVA 346
G F +HP + L++ V F L++K +Q + + + +E +
Sbjct: 328 VGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHPLPAFAGLHIEILD 387
Query: 347 AAGSPPRFPQRLYRGTVARGAGAGVVVKDAAAPSQPLRIQAQDPEFSD 394
P F Y+G + A G + D+ + PLRI A D + D
Sbjct: 388 ENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIED 435
Score = 44.7 bits (104), Expect = 4e-04
Identities = 101/420 (24%), Positives = 157/420 (37%), Gaps = 73/420 (17%)
Query: 71 FRIQGN-QLFLNVTPDYEEKSLLEAQLLCQSGGTLV--TQLRVFVSVLDVNDNAPEFPFK 127
FRI N ++ V + E + E ++ G + L + + VLD++DN+P F
Sbjct: 763 FRITSNGSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNS 822
Query: 128 TKEIRVEEDTKVNSTVIPETQLQAEDRDKDDILFYTLQEMTAGASDYFSLVSVNRPALRL 187
T + VEE+ +T++ Q++A+D D + Y ++ +F + L L
Sbjct: 823 TYTVLVEENLPAGTTIL---QIEAKDVDLGANVSYRIRSPEV---KHFFALHPFTGELSL 876
Query: 188 DRPLDFYERP----NMTFWLLVRDTPGENVEPSHTATATLVLNVVPADLRPPWFLPCTFS 243
R LD+ P ++TF + D G P AT T++ V + PP F
Sbjct: 877 LRSLDYEAFPDQEASITFLVEAFDIYG--TMPPGIATVTVI--VKDMNDYPPVF------ 926
Query: 244 DGYVCIQAQYHGAVPTGHILPSPLVLRPGPIYAEDGD-------------RGINQPIIYS 290
+ Y G V + +P+ +YAED D + P S
Sbjct: 927 -----SKRIYKGMVAPDAVKGTPIT----TVYAEDADPPGLPASRVRYRVDDVQFPYPAS 977
Query: 291 IFRGNVNGTFIIHPDSGN-LTVARSVPSPMTFLLLVKGQQADLARYSVTQVTVE-AVAAA 348
IF + DSG +T P T LV D + TV+ V
Sbjct: 978 IFE--------VEEDSGRVITRVNLNEEPTTIFKLVVVAFDDGEPVMSSSATVKILVLHP 1029
Query: 349 GSPPRFPQRLYR-----GTVARGAGAGVVVKDAAAPSQPL---RIQAQDPEFSDLNSAIT 400
G PRF Q YR +G GV+ AAA +Q + + + + +N+
Sbjct: 1030 GEIPRFTQEEYRPPPVSELATKGTMVGVI--SAAAINQSIVYSIVSGNEEDTFGINN--- 1084
Query: 401 YRITNHSHFRMEGEVVLTTTTLAQAGAFYAEVEAHN---TVTSGTATTVIEIQVSEQEPP 457
IT + + T+ + + A EV N S TA IEIQ PP
Sbjct: 1085 --ITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPP 1142
Score = 40.4 bits (93), Expect = 0.007
Identities = 73/383 (19%), Positives = 149/383 (38%), Gaps = 48/383 (12%)
Query: 39 VEENTNVTEPLVDIHVPEGQEVT--------LGALSTPFAFRIQGNQLFLNVTP--DYEE 88
+ ++ N+T PL + + + E T L ++ F G +L + D EE
Sbjct: 414 ISDSLNLTSPLRIVALDKDIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREE 473
Query: 89 KSLLEAQLLCQSGGTLVTQLRVFVSVLDVNDNAPEFPFKTKEIRVEEDTKVNSTVIPETQ 148
+ + G + V + V+D NDN P FP + ++ V D + +VI T
Sbjct: 474 QQTYTFSITAFDGVQESEPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTA 533
Query: 149 LQAEDRDKDDILFYTLQEMTAGASDYFSLVSVNRPALRLDRPLDFYERPNMTFWLLVRDT 208
+ A++ +I + E+ GA F +++ + + ++ T+ L V+
Sbjct: 534 VDADEGSNGEITY----EILVGAQGDF-IINKTTGLITIAPGVEMI--VGRTYALTVQAA 586
Query: 209 PGENVEPSHTATATLVLNVVPADLR-PPWFLPCTFSDGYVCIQAQYHGAVPTGHILPSPL 267
+ T+ + V+P + + PP F +S + A+ G +L +
Sbjct: 587 DNAPPAERRNSICTVYIEVLPPNNQSPPRFPQLMYS-------LEISEAMRVGAVLLN-- 637
Query: 268 VLRPGPIYAEDGDRGINQPIIYSIFRGNVNGTFIIHPDSGNLTVARSVPSPMT--FLLLV 325
+ A D + I Y+I G+ F + +G LT+ +++ T ++L++
Sbjct: 638 ------LQATDRE---GDSITYAIENGDPQRVFNLSETTGILTLGKALDRESTDRYILII 688
Query: 326 KGQQADLARYSVTQVTVEAVAAAGSPPRFPQRLYRGTVARGAGAGVVVKDAAAPSQPLRI 385
S V + + P F L R + V + A + ++
Sbjct: 689 TASDGRPDGTSTATVNIVVTDVNDNAPVFDPYLPR---------NLSVVEEEANAFVGQV 739
Query: 386 QAQDPEFSDLNSAITYRITNHSH 408
+A DP+ + +N + Y + N ++
Sbjct: 740 KATDPD-AGINGQVHYSLGNFNN 761
Score = 32.7 bits (73), Expect = 1.4
Identities = 19/55 (34%), Positives = 25/55 (45%), Gaps = 4/55 (7%)
Query: 713 FDNQAFLPDHKANWAPVPSPTHDPKPAEAPMPAEPAPPGPASPGG----APEPPA 763
F+N A P+ + P+P P P+ P PA APP SP P PP+
Sbjct: 1731 FENFAHPPNISPSACPLPPPPPISPPSPPPAPAPLAPPPDISPFSLFCPPPSPPS 1785
Score = 30.8 bits (68), Expect = 5.5
Identities = 28/88 (31%), Positives = 34/88 (38%), Gaps = 10/88 (11%)
Query: 505 PSGTTLRPPTSSTPGGPPGAENSTSHQP-ATPGGDTAQTPK-PGTSQPMPP----GVGTS 558
PS L PP +P PP A + P +P P P P+PP + S
Sbjct: 1742 PSACPLPPPPPISPPSPPPAPAPLAPPPDISPFSLFCPPPSPPSIPLPLPPPTFFPLSVS 1801
Query: 559 TSHQPATPSGGTAQTPEPGTSQPMPPSM 586
TS P P TP P P PPS+
Sbjct: 1802 TSGPPTPPLLPPFPTPLP----PPPPSI 1825
Score = 30.8 bits (68), Expect = 5.5
Identities = 25/78 (32%), Positives = 33/78 (42%), Gaps = 6/78 (7%)
Query: 451 VSEQEPPSTDVP--PSPEAGGTT---GPWTSTTSEVPRPPEPSQGPSTTSSGGGTGPH-P 504
+S PP P P P+ + P + + +P PP S ++SG T P P
Sbjct: 1753 ISPPSPPPAPAPLAPPPDISPFSLFCPPPSPPSIPLPLPPPTFFPLSVSTSGPPTPPLLP 1812
Query: 505 PSGTTLRPPTSSTPGGPP 522
P T L PP S P PP
Sbjct: 1813 PFPTPLPPPPPSIPCPPP 1830
>gi|218505798 protocadherin 15 isoform CD1-10 precursor [Homo
sapiens]
Length = 1932
Score = 80.1 bits (196), Expect = 8e-15
Identities = 91/348 (26%), Positives = 147/348 (42%), Gaps = 37/348 (10%)
Query: 78 LFLNVT--------PDYEEKSLLEAQLLCQSGGTLVTQLRVFVSVLDVNDNAPEFPFKTK 129
LFLN T P +++ Q + + GT++ V + V D NDN+P F ++
Sbjct: 72 LFLNSTGRVLDRDPPMNIHSIVVQVQCINKKVGTIIYH-EVRIVVRDRNDNSPTFKHESY 130
Query: 130 EIRVEEDTKVNSTVIPETQLQAEDRDKDD--------ILFYTLQEMTAGASDYFSLVSVN 181
V E T V +T+ D DD ++ Y + T+ +D F + +
Sbjct: 131 YATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYNPDDPTS--NDTFEIPLML 188
Query: 182 RPALRLDRPLDFYERPNMTFWLLVRDTPGENVEPSHTATATLVLNVVPADLRPPWFLPCT 241
+ L + L+ YE F ++ + +N+ T T TL ++V+ D P FLPC
Sbjct: 189 TGNIVLRKRLN-YEDKTRYFVIIQANDRAQNLNERRTTTTTLTVDVLDGDDLGPMFLPCV 247
Query: 242 F-SDGYVCIQAQYHGAVP---TGHILPSPLVLRPGPIYAEDGDRGINQP-----IIYSIF 292
+ C Y A+P T L +P+++ P PI A D DR I P I+YSI
Sbjct: 248 LVPNTRDCRPLTYQAAIPELRTPEEL-NPIIVTP-PIQAIDQDRNIQPPSDRPGILYSIL 305
Query: 293 RGNVNG---TFIIHPDSGNLTVARSVPSP--MTFLLLVKGQQAD-LARYSVTQVTVEAVA 346
G F +HP + L++ V F L++K +Q + + + +E +
Sbjct: 306 VGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHPLPAFAGLHIEILD 365
Query: 347 AAGSPPRFPQRLYRGTVARGAGAGVVVKDAAAPSQPLRIQAQDPEFSD 394
P F Y+G + A G + D+ + PLRI A D + D
Sbjct: 366 ENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIED 413
Score = 44.7 bits (104), Expect = 4e-04
Identities = 101/420 (24%), Positives = 157/420 (37%), Gaps = 73/420 (17%)
Query: 71 FRIQGN-QLFLNVTPDYEEKSLLEAQLLCQSGGTLV--TQLRVFVSVLDVNDNAPEFPFK 127
FRI N ++ V + E + E ++ G + L + + VLD++DN+P F
Sbjct: 741 FRITSNGSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNS 800
Query: 128 TKEIRVEEDTKVNSTVIPETQLQAEDRDKDDILFYTLQEMTAGASDYFSLVSVNRPALRL 187
T + VEE+ +T++ Q++A+D D + Y ++ +F + L L
Sbjct: 801 TYTVLVEENLPAGTTIL---QIEAKDVDLGANVSYRIRSPEV---KHFFALHPFTGELSL 854
Query: 188 DRPLDFYERP----NMTFWLLVRDTPGENVEPSHTATATLVLNVVPADLRPPWFLPCTFS 243
R LD+ P ++TF + D G P AT T++ V + PP F
Sbjct: 855 LRSLDYEAFPDQEASITFLVEAFDIYG--TMPPGIATVTVI--VKDMNDYPPVF------ 904
Query: 244 DGYVCIQAQYHGAVPTGHILPSPLVLRPGPIYAEDGD-------------RGINQPIIYS 290
+ Y G V + +P+ +YAED D + P S
Sbjct: 905 -----SKRIYKGMVAPDAVKGTPIT----TVYAEDADPPGLPASRVRYRVDDVQFPYPAS 955
Query: 291 IFRGNVNGTFIIHPDSGN-LTVARSVPSPMTFLLLVKGQQADLARYSVTQVTVE-AVAAA 348
IF + DSG +T P T LV D + TV+ V
Sbjct: 956 IFE--------VEEDSGRVITRVNLNEEPTTIFKLVVVAFDDGEPVMSSSATVKILVLHP 1007
Query: 349 GSPPRFPQRLYR-----GTVARGAGAGVVVKDAAAPSQPL---RIQAQDPEFSDLNSAIT 400
G PRF Q YR +G GV+ AAA +Q + + + + +N+
Sbjct: 1008 GEIPRFTQEEYRPPPVSELATKGTMVGVI--SAAAINQSIVYSIVSGNEEDTFGINN--- 1062
Query: 401 YRITNHSHFRMEGEVVLTTTTLAQAGAFYAEVEAHN---TVTSGTATTVIEIQVSEQEPP 457
IT + + T+ + + A EV N S TA IEIQ PP
Sbjct: 1063 --ITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPP 1120
Score = 40.4 bits (93), Expect = 0.007
Identities = 73/383 (19%), Positives = 149/383 (38%), Gaps = 48/383 (12%)
Query: 39 VEENTNVTEPLVDIHVPEGQEVT--------LGALSTPFAFRIQGNQLFLNVTP--DYEE 88
+ ++ N+T PL + + + E T L ++ F G +L + D EE
Sbjct: 392 ISDSLNLTSPLRIVALDKDIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREE 451
Query: 89 KSLLEAQLLCQSGGTLVTQLRVFVSVLDVNDNAPEFPFKTKEIRVEEDTKVNSTVIPETQ 148
+ + G + V + V+D NDN P FP + ++ V D + +VI T
Sbjct: 452 QQTYTFSITAFDGVQESEPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTA 511
Query: 149 LQAEDRDKDDILFYTLQEMTAGASDYFSLVSVNRPALRLDRPLDFYERPNMTFWLLVRDT 208
+ A++ +I + E+ GA F +++ + + ++ T+ L V+
Sbjct: 512 VDADEGSNGEITY----EILVGAQGDF-IINKTTGLITIAPGVEMI--VGRTYALTVQAA 564
Query: 209 PGENVEPSHTATATLVLNVVPADLR-PPWFLPCTFSDGYVCIQAQYHGAVPTGHILPSPL 267
+ T+ + V+P + + PP F +S + A+ G +L +
Sbjct: 565 DNAPPAERRNSICTVYIEVLPPNNQSPPRFPQLMYS-------LEISEAMRVGAVLLN-- 615
Query: 268 VLRPGPIYAEDGDRGINQPIIYSIFRGNVNGTFIIHPDSGNLTVARSVPSPMT--FLLLV 325
+ A D + I Y+I G+ F + +G LT+ +++ T ++L++
Sbjct: 616 ------LQATDRE---GDSITYAIENGDPQRVFNLSETTGILTLGKALDRESTDRYILII 666
Query: 326 KGQQADLARYSVTQVTVEAVAAAGSPPRFPQRLYRGTVARGAGAGVVVKDAAAPSQPLRI 385
S V + + P F L R + V + A + ++
Sbjct: 667 TASDGRPDGTSTATVNIVVTDVNDNAPVFDPYLPR---------NLSVVEEEANAFVGQV 717
Query: 386 QAQDPEFSDLNSAITYRITNHSH 408
+A DP+ + +N + Y + N ++
Sbjct: 718 KATDPD-AGINGQVHYSLGNFNN 739
Score = 32.7 bits (73), Expect = 1.4
Identities = 19/55 (34%), Positives = 25/55 (45%), Gaps = 4/55 (7%)
Query: 713 FDNQAFLPDHKANWAPVPSPTHDPKPAEAPMPAEPAPPGPASPGG----APEPPA 763
F+N A P+ + P+P P P+ P PA APP SP P PP+
Sbjct: 1708 FENFAHPPNISPSACPLPPPPPISPPSPPPAPAPLAPPPDISPFSLFCPPPSPPS 1762
Score = 30.8 bits (68), Expect = 5.5
Identities = 28/88 (31%), Positives = 34/88 (38%), Gaps = 10/88 (11%)
Query: 505 PSGTTLRPPTSSTPGGPPGAENSTSHQP-ATPGGDTAQTPK-PGTSQPMPP----GVGTS 558
PS L PP +P PP A + P +P P P P+PP + S
Sbjct: 1719 PSACPLPPPPPISPPSPPPAPAPLAPPPDISPFSLFCPPPSPPSIPLPLPPPTFFPLSVS 1778
Query: 559 TSHQPATPSGGTAQTPEPGTSQPMPPSM 586
TS P P TP P P PPS+
Sbjct: 1779 TSGPPTPPLLPPFPTPLP----PPPPSI 1802
Score = 30.8 bits (68), Expect = 5.5
Identities = 25/78 (32%), Positives = 33/78 (42%), Gaps = 6/78 (7%)
Query: 451 VSEQEPPSTDVP--PSPEAGGTT---GPWTSTTSEVPRPPEPSQGPSTTSSGGGTGPH-P 504
+S PP P P P+ + P + + +P PP S ++SG T P P
Sbjct: 1730 ISPPSPPPAPAPLAPPPDISPFSLFCPPPSPPSIPLPLPPPTFFPLSVSTSGPPTPPLLP 1789
Query: 505 PSGTTLRPPTSSTPGGPP 522
P T L PP S P PP
Sbjct: 1790 PFPTPLPPPPPSIPCPPP 1807
>gi|218505793 protocadherin 15 isoform CD3-2 precursor [Homo
sapiens]
Length = 1677
Score = 80.1 bits (196), Expect = 8e-15
Identities = 91/348 (26%), Positives = 147/348 (42%), Gaps = 37/348 (10%)
Query: 78 LFLNVT--------PDYEEKSLLEAQLLCQSGGTLVTQLRVFVSVLDVNDNAPEFPFKTK 129
LFLN T P +++ Q + + GT++ V + V D NDN+P F ++
Sbjct: 94 LFLNSTGRVLDRDPPMNIHSIVVQVQCINKKVGTIIYH-EVRIVVRDRNDNSPTFKHESY 152
Query: 130 EIRVEEDTKVNSTVIPETQLQAEDRDKDD--------ILFYTLQEMTAGASDYFSLVSVN 181
V E T V +T+ D DD ++ Y + T+ +D F + +
Sbjct: 153 YATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYNPDDPTS--NDTFEIPLML 210
Query: 182 RPALRLDRPLDFYERPNMTFWLLVRDTPGENVEPSHTATATLVLNVVPADLRPPWFLPCT 241
+ L + L+ YE F ++ + +N+ T T TL ++V+ D P FLPC
Sbjct: 211 TGNIVLRKRLN-YEDKTRYFVIIQANDRAQNLNERRTTTTTLTVDVLDGDDLGPMFLPCV 269
Query: 242 F-SDGYVCIQAQYHGAVP---TGHILPSPLVLRPGPIYAEDGDRGINQP-----IIYSIF 292
+ C Y A+P T L +P+++ P PI A D DR I P I+YSI
Sbjct: 270 LVPNTRDCRPLTYQAAIPELRTPEEL-NPIIVTP-PIQAIDQDRNIQPPSDRPGILYSIL 327
Query: 293 RGNVNG---TFIIHPDSGNLTVARSVPSP--MTFLLLVKGQQAD-LARYSVTQVTVEAVA 346
G F +HP + L++ V F L++K +Q + + + +E +
Sbjct: 328 VGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHPLPAFAGLHIEILD 387
Query: 347 AAGSPPRFPQRLYRGTVARGAGAGVVVKDAAAPSQPLRIQAQDPEFSD 394
P F Y+G + A G + D+ + PLRI A D + D
Sbjct: 388 ENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIED 435
Score = 44.7 bits (104), Expect = 4e-04
Identities = 101/420 (24%), Positives = 157/420 (37%), Gaps = 73/420 (17%)
Query: 71 FRIQGN-QLFLNVTPDYEEKSLLEAQLLCQSGGTLV--TQLRVFVSVLDVNDNAPEFPFK 127
FRI N ++ V + E + E ++ G + L + + VLD++DN+P F
Sbjct: 763 FRITSNGSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNS 822
Query: 128 TKEIRVEEDTKVNSTVIPETQLQAEDRDKDDILFYTLQEMTAGASDYFSLVSVNRPALRL 187
T + VEE+ +T++ Q++A+D D + Y ++ +F + L L
Sbjct: 823 TYTVLVEENLPAGTTIL---QIEAKDVDLGANVSYRIRSPEV---KHFFALHPFTGELSL 876
Query: 188 DRPLDFYERP----NMTFWLLVRDTPGENVEPSHTATATLVLNVVPADLRPPWFLPCTFS 243
R LD+ P ++TF + D G P AT T++ V + PP F
Sbjct: 877 LRSLDYEAFPDQEASITFLVEAFDIYG--TMPPGIATVTVI--VKDMNDYPPVF------ 926
Query: 244 DGYVCIQAQYHGAVPTGHILPSPLVLRPGPIYAEDGD-------------RGINQPIIYS 290
+ Y G V + +P+ +YAED D + P S
Sbjct: 927 -----SKRIYKGMVAPDAVKGTPIT----TVYAEDADPPGLPASRVRYRVDDVQFPYPAS 977
Query: 291 IFRGNVNGTFIIHPDSGN-LTVARSVPSPMTFLLLVKGQQADLARYSVTQVTVE-AVAAA 348
IF + DSG +T P T LV D + TV+ V
Sbjct: 978 IFE--------VEEDSGRVITRVNLNEEPTTIFKLVVVAFDDGEPVMSSSATVKILVLHP 1029
Query: 349 GSPPRFPQRLYR-----GTVARGAGAGVVVKDAAAPSQPL---RIQAQDPEFSDLNSAIT 400
G PRF Q YR +G GV+ AAA +Q + + + + +N+
Sbjct: 1030 GEIPRFTQEEYRPPPVSELATKGTMVGVI--SAAAINQSIVYSIVSGNEEDTFGINN--- 1084
Query: 401 YRITNHSHFRMEGEVVLTTTTLAQAGAFYAEVEAHN---TVTSGTATTVIEIQVSEQEPP 457
IT + + T+ + + A EV N S TA IEIQ PP
Sbjct: 1085 --ITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPP 1142
Score = 40.4 bits (93), Expect = 0.007
Identities = 73/383 (19%), Positives = 149/383 (38%), Gaps = 48/383 (12%)
Query: 39 VEENTNVTEPLVDIHVPEGQEVT--------LGALSTPFAFRIQGNQLFLNVTP--DYEE 88
+ ++ N+T PL + + + E T L ++ F G +L + D EE
Sbjct: 414 ISDSLNLTSPLRIVALDKDIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREE 473
Query: 89 KSLLEAQLLCQSGGTLVTQLRVFVSVLDVNDNAPEFPFKTKEIRVEEDTKVNSTVIPETQ 148
+ + G + V + V+D NDN P FP + ++ V D + +VI T
Sbjct: 474 QQTYTFSITAFDGVQESEPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTA 533
Query: 149 LQAEDRDKDDILFYTLQEMTAGASDYFSLVSVNRPALRLDRPLDFYERPNMTFWLLVRDT 208
+ A++ +I + E+ GA F +++ + + ++ T+ L V+
Sbjct: 534 VDADEGSNGEITY----EILVGAQGDF-IINKTTGLITIAPGVEMI--VGRTYALTVQAA 586
Query: 209 PGENVEPSHTATATLVLNVVPADLR-PPWFLPCTFSDGYVCIQAQYHGAVPTGHILPSPL 267
+ T+ + V+P + + PP F +S + A+ G +L +
Sbjct: 587 DNAPPAERRNSICTVYIEVLPPNNQSPPRFPQLMYS-------LEISEAMRVGAVLLN-- 637
Query: 268 VLRPGPIYAEDGDRGINQPIIYSIFRGNVNGTFIIHPDSGNLTVARSVPSPMT--FLLLV 325
+ A D + I Y+I G+ F + +G LT+ +++ T ++L++
Sbjct: 638 ------LQATDRE---GDSITYAIENGDPQRVFNLSETTGILTLGKALDRESTDRYILII 688
Query: 326 KGQQADLARYSVTQVTVEAVAAAGSPPRFPQRLYRGTVARGAGAGVVVKDAAAPSQPLRI 385
S V + + P F L R + V + A + ++
Sbjct: 689 TASDGRPDGTSTATVNIVVTDVNDNAPVFDPYLPR---------NLSVVEEEANAFVGQV 739
Query: 386 QAQDPEFSDLNSAITYRITNHSH 408
+A DP+ + +N + Y + N ++
Sbjct: 740 KATDPD-AGINGQVHYSLGNFNN 761
>gi|218505791 protocadherin 15 isoform CD3-1 precursor [Homo
sapiens]
Length = 1682
Score = 80.1 bits (196), Expect = 8e-15
Identities = 91/348 (26%), Positives = 147/348 (42%), Gaps = 37/348 (10%)
Query: 78 LFLNVT--------PDYEEKSLLEAQLLCQSGGTLVTQLRVFVSVLDVNDNAPEFPFKTK 129
LFLN T P +++ Q + + GT++ V + V D NDN+P F ++
Sbjct: 99 LFLNSTGRVLDRDPPMNIHSIVVQVQCINKKVGTIIYH-EVRIVVRDRNDNSPTFKHESY 157
Query: 130 EIRVEEDTKVNSTVIPETQLQAEDRDKDD--------ILFYTLQEMTAGASDYFSLVSVN 181
V E T V +T+ D DD ++ Y + T+ +D F + +
Sbjct: 158 YATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYNPDDPTS--NDTFEIPLML 215
Query: 182 RPALRLDRPLDFYERPNMTFWLLVRDTPGENVEPSHTATATLVLNVVPADLRPPWFLPCT 241
+ L + L+ YE F ++ + +N+ T T TL ++V+ D P FLPC
Sbjct: 216 TGNIVLRKRLN-YEDKTRYFVIIQANDRAQNLNERRTTTTTLTVDVLDGDDLGPMFLPCV 274
Query: 242 F-SDGYVCIQAQYHGAVP---TGHILPSPLVLRPGPIYAEDGDRGINQP-----IIYSIF 292
+ C Y A+P T L +P+++ P PI A D DR I P I+YSI
Sbjct: 275 LVPNTRDCRPLTYQAAIPELRTPEEL-NPIIVTP-PIQAIDQDRNIQPPSDRPGILYSIL 332
Query: 293 RGNVNG---TFIIHPDSGNLTVARSVPSP--MTFLLLVKGQQAD-LARYSVTQVTVEAVA 346
G F +HP + L++ V F L++K +Q + + + +E +
Sbjct: 333 VGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHPLPAFAGLHIEILD 392
Query: 347 AAGSPPRFPQRLYRGTVARGAGAGVVVKDAAAPSQPLRIQAQDPEFSD 394
P F Y+G + A G + D+ + PLRI A D + D
Sbjct: 393 ENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIED 440
Score = 44.7 bits (104), Expect = 4e-04
Identities = 101/420 (24%), Positives = 157/420 (37%), Gaps = 73/420 (17%)
Query: 71 FRIQGN-QLFLNVTPDYEEKSLLEAQLLCQSGGTLV--TQLRVFVSVLDVNDNAPEFPFK 127
FRI N ++ V + E + E ++ G + L + + VLD++DN+P F
Sbjct: 768 FRITSNGSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNS 827
Query: 128 TKEIRVEEDTKVNSTVIPETQLQAEDRDKDDILFYTLQEMTAGASDYFSLVSVNRPALRL 187
T + VEE+ +T++ Q++A+D D + Y ++ +F + L L
Sbjct: 828 TYTVLVEENLPAGTTIL---QIEAKDVDLGANVSYRIRSPEV---KHFFALHPFTGELSL 881
Query: 188 DRPLDFYERP----NMTFWLLVRDTPGENVEPSHTATATLVLNVVPADLRPPWFLPCTFS 243
R LD+ P ++TF + D G P AT T++ V + PP F
Sbjct: 882 LRSLDYEAFPDQEASITFLVEAFDIYG--TMPPGIATVTVI--VKDMNDYPPVF------ 931
Query: 244 DGYVCIQAQYHGAVPTGHILPSPLVLRPGPIYAEDGD-------------RGINQPIIYS 290
+ Y G V + +P+ +YAED D + P S
Sbjct: 932 -----SKRIYKGMVAPDAVKGTPIT----TVYAEDADPPGLPASRVRYRVDDVQFPYPAS 982
Query: 291 IFRGNVNGTFIIHPDSGN-LTVARSVPSPMTFLLLVKGQQADLARYSVTQVTVE-AVAAA 348
IF + DSG +T P T LV D + TV+ V
Sbjct: 983 IFE--------VEEDSGRVITRVNLNEEPTTIFKLVVVAFDDGEPVMSSSATVKILVLHP 1034
Query: 349 GSPPRFPQRLYR-----GTVARGAGAGVVVKDAAAPSQPL---RIQAQDPEFSDLNSAIT 400
G PRF Q YR +G GV+ AAA +Q + + + + +N+
Sbjct: 1035 GEIPRFTQEEYRPPPVSELATKGTMVGVI--SAAAINQSIVYSIVSGNEEDTFGINN--- 1089
Query: 401 YRITNHSHFRMEGEVVLTTTTLAQAGAFYAEVEAHN---TVTSGTATTVIEIQVSEQEPP 457
IT + + T+ + + A EV N S TA IEIQ PP
Sbjct: 1090 --ITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPP 1147
Score = 40.4 bits (93), Expect = 0.007
Identities = 73/383 (19%), Positives = 149/383 (38%), Gaps = 48/383 (12%)
Query: 39 VEENTNVTEPLVDIHVPEGQEVT--------LGALSTPFAFRIQGNQLFLNVTP--DYEE 88
+ ++ N+T PL + + + E T L ++ F G +L + D EE
Sbjct: 419 ISDSLNLTSPLRIVALDKDIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREE 478
Query: 89 KSLLEAQLLCQSGGTLVTQLRVFVSVLDVNDNAPEFPFKTKEIRVEEDTKVNSTVIPETQ 148
+ + G + V + V+D NDN P FP + ++ V D + +VI T
Sbjct: 479 QQTYTFSITAFDGVQESEPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTA 538
Query: 149 LQAEDRDKDDILFYTLQEMTAGASDYFSLVSVNRPALRLDRPLDFYERPNMTFWLLVRDT 208
+ A++ +I + E+ GA F +++ + + ++ T+ L V+
Sbjct: 539 VDADEGSNGEITY----EILVGAQGDF-IINKTTGLITIAPGVEMI--VGRTYALTVQAA 591
Query: 209 PGENVEPSHTATATLVLNVVPADLR-PPWFLPCTFSDGYVCIQAQYHGAVPTGHILPSPL 267
+ T+ + V+P + + PP F +S + A+ G +L +
Sbjct: 592 DNAPPAERRNSICTVYIEVLPPNNQSPPRFPQLMYS-------LEISEAMRVGAVLLN-- 642
Query: 268 VLRPGPIYAEDGDRGINQPIIYSIFRGNVNGTFIIHPDSGNLTVARSVPSPMT--FLLLV 325
+ A D + I Y+I G+ F + +G LT+ +++ T ++L++
Sbjct: 643 ------LQATDRE---GDSITYAIENGDPQRVFNLSETTGILTLGKALDRESTDRYILII 693
Query: 326 KGQQADLARYSVTQVTVEAVAAAGSPPRFPQRLYRGTVARGAGAGVVVKDAAAPSQPLRI 385
S V + + P F L R + V + A + ++
Sbjct: 694 TASDGRPDGTSTATVNIVVTDVNDNAPVFDPYLPR---------NLSVVEEEANAFVGQV 744
Query: 386 QAQDPEFSDLNSAITYRITNHSH 408
+A DP+ + +N + Y + N ++
Sbjct: 745 KATDPD-AGINGQVHYSLGNFNN 766
>gi|218505789 protocadherin 15 isoform CD2-2 precursor [Homo
sapiens]
Length = 1539
Score = 80.1 bits (196), Expect = 8e-15
Identities = 91/348 (26%), Positives = 147/348 (42%), Gaps = 37/348 (10%)
Query: 78 LFLNVT--------PDYEEKSLLEAQLLCQSGGTLVTQLRVFVSVLDVNDNAPEFPFKTK 129
LFLN T P +++ Q + + GT++ V + V D NDN+P F ++
Sbjct: 94 LFLNSTGRVLDRDPPMNIHSIVVQVQCINKKVGTIIYH-EVRIVVRDRNDNSPTFKHESY 152
Query: 130 EIRVEEDTKVNSTVIPETQLQAEDRDKDD--------ILFYTLQEMTAGASDYFSLVSVN 181
V E T V +T+ D DD ++ Y + T+ +D F + +
Sbjct: 153 YATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYNPDDPTS--NDTFEIPLML 210
Query: 182 RPALRLDRPLDFYERPNMTFWLLVRDTPGENVEPSHTATATLVLNVVPADLRPPWFLPCT 241
+ L + L+ YE F ++ + +N+ T T TL ++V+ D P FLPC
Sbjct: 211 TGNIVLRKRLN-YEDKTRYFVIIQANDRAQNLNERRTTTTTLTVDVLDGDDLGPMFLPCV 269
Query: 242 F-SDGYVCIQAQYHGAVP---TGHILPSPLVLRPGPIYAEDGDRGINQP-----IIYSIF 292
+ C Y A+P T L +P+++ P PI A D DR I P I+YSI
Sbjct: 270 LVPNTRDCRPLTYQAAIPELRTPEEL-NPIIVTP-PIQAIDQDRNIQPPSDRPGILYSIL 327
Query: 293 RGNVNG---TFIIHPDSGNLTVARSVPSP--MTFLLLVKGQQAD-LARYSVTQVTVEAVA 346
G F +HP + L++ V F L++K +Q + + + +E +
Sbjct: 328 VGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHPLPAFAGLHIEILD 387
Query: 347 AAGSPPRFPQRLYRGTVARGAGAGVVVKDAAAPSQPLRIQAQDPEFSD 394
P F Y+G + A G + D+ + PLRI A D + D
Sbjct: 388 ENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIED 435
Score = 44.7 bits (104), Expect = 4e-04
Identities = 101/420 (24%), Positives = 157/420 (37%), Gaps = 73/420 (17%)
Query: 71 FRIQGN-QLFLNVTPDYEEKSLLEAQLLCQSGGTLV--TQLRVFVSVLDVNDNAPEFPFK 127
FRI N ++ V + E + E ++ G + L + + VLD++DN+P F
Sbjct: 763 FRITSNGSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNS 822
Query: 128 TKEIRVEEDTKVNSTVIPETQLQAEDRDKDDILFYTLQEMTAGASDYFSLVSVNRPALRL 187
T + VEE+ +T++ Q++A+D D + Y ++ +F + L L
Sbjct: 823 TYTVLVEENLPAGTTIL---QIEAKDVDLGANVSYRIRSPEV---KHFFALHPFTGELSL 876
Query: 188 DRPLDFYERP----NMTFWLLVRDTPGENVEPSHTATATLVLNVVPADLRPPWFLPCTFS 243
R LD+ P ++TF + D G P AT T++ V + PP F
Sbjct: 877 LRSLDYEAFPDQEASITFLVEAFDIYG--TMPPGIATVTVI--VKDMNDYPPVF------ 926
Query: 244 DGYVCIQAQYHGAVPTGHILPSPLVLRPGPIYAEDGD-------------RGINQPIIYS 290
+ Y G V + +P+ +YAED D + P S
Sbjct: 927 -----SKRIYKGMVAPDAVKGTPIT----TVYAEDADPPGLPASRVRYRVDDVQFPYPAS 977
Query: 291 IFRGNVNGTFIIHPDSGN-LTVARSVPSPMTFLLLVKGQQADLARYSVTQVTVE-AVAAA 348
IF + DSG +T P T LV D + TV+ V
Sbjct: 978 IFE--------VEEDSGRVITRVNLNEEPTTIFKLVVVAFDDGEPVMSSSATVKILVLHP 1029
Query: 349 GSPPRFPQRLYR-----GTVARGAGAGVVVKDAAAPSQPL---RIQAQDPEFSDLNSAIT 400
G PRF Q YR +G GV+ AAA +Q + + + + +N+
Sbjct: 1030 GEIPRFTQEEYRPPPVSELATKGTMVGVI--SAAAINQSIVYSIVSGNEEDTFGINN--- 1084
Query: 401 YRITNHSHFRMEGEVVLTTTTLAQAGAFYAEVEAHN---TVTSGTATTVIEIQVSEQEPP 457
IT + + T+ + + A EV N S TA IEIQ PP
Sbjct: 1085 --ITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPP 1142
Score = 40.4 bits (93), Expect = 0.007
Identities = 73/383 (19%), Positives = 149/383 (38%), Gaps = 48/383 (12%)
Query: 39 VEENTNVTEPLVDIHVPEGQEVT--------LGALSTPFAFRIQGNQLFLNVTP--DYEE 88
+ ++ N+T PL + + + E T L ++ F G +L + D EE
Sbjct: 414 ISDSLNLTSPLRIVALDKDIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREE 473
Query: 89 KSLLEAQLLCQSGGTLVTQLRVFVSVLDVNDNAPEFPFKTKEIRVEEDTKVNSTVIPETQ 148
+ + G + V + V+D NDN P FP + ++ V D + +VI T
Sbjct: 474 QQTYTFSITAFDGVQESEPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTA 533
Query: 149 LQAEDRDKDDILFYTLQEMTAGASDYFSLVSVNRPALRLDRPLDFYERPNMTFWLLVRDT 208
+ A++ +I + E+ GA F +++ + + ++ T+ L V+
Sbjct: 534 VDADEGSNGEITY----EILVGAQGDF-IINKTTGLITIAPGVEMI--VGRTYALTVQAA 586
Query: 209 PGENVEPSHTATATLVLNVVPADLR-PPWFLPCTFSDGYVCIQAQYHGAVPTGHILPSPL 267
+ T+ + V+P + + PP F +S + A+ G +L +
Sbjct: 587 DNAPPAERRNSICTVYIEVLPPNNQSPPRFPQLMYS-------LEISEAMRVGAVLLN-- 637
Query: 268 VLRPGPIYAEDGDRGINQPIIYSIFRGNVNGTFIIHPDSGNLTVARSVPSPMT--FLLLV 325
+ A D + I Y+I G+ F + +G LT+ +++ T ++L++
Sbjct: 638 ------LQATDRE---GDSITYAIENGDPQRVFNLSETTGILTLGKALDRESTDRYILII 688
Query: 326 KGQQADLARYSVTQVTVEAVAAAGSPPRFPQRLYRGTVARGAGAGVVVKDAAAPSQPLRI 385
S V + + P F L R + V + A + ++
Sbjct: 689 TASDGRPDGTSTATVNIVVTDVNDNAPVFDPYLPR---------NLSVVEEEANAFVGQV 739
Query: 386 QAQDPEFSDLNSAITYRITNHSH 408
+A DP+ + +N + Y + N ++
Sbjct: 740 KATDPD-AGINGQVHYSLGNFNN 761
>gi|218505785 protocadherin 15 isoform CD1-9 precursor [Homo
sapiens]
Length = 1935
Score = 80.1 bits (196), Expect = 8e-15
Identities = 91/348 (26%), Positives = 147/348 (42%), Gaps = 37/348 (10%)
Query: 78 LFLNVT--------PDYEEKSLLEAQLLCQSGGTLVTQLRVFVSVLDVNDNAPEFPFKTK 129
LFLN T P +++ Q + + GT++ V + V D NDN+P F ++
Sbjct: 72 LFLNSTGRVLDRDPPMNIHSIVVQVQCINKKVGTIIYH-EVRIVVRDRNDNSPTFKHESY 130
Query: 130 EIRVEEDTKVNSTVIPETQLQAEDRDKDD--------ILFYTLQEMTAGASDYFSLVSVN 181
V E T V +T+ D DD ++ Y + T+ +D F + +
Sbjct: 131 YATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYNPDDPTS--NDTFEIPLML 188
Query: 182 RPALRLDRPLDFYERPNMTFWLLVRDTPGENVEPSHTATATLVLNVVPADLRPPWFLPCT 241
+ L + L+ YE F ++ + +N+ T T TL ++V+ D P FLPC
Sbjct: 189 TGNIVLRKRLN-YEDKTRYFVIIQANDRAQNLNERRTTTTTLTVDVLDGDDLGPMFLPCV 247
Query: 242 F-SDGYVCIQAQYHGAVP---TGHILPSPLVLRPGPIYAEDGDRGINQP-----IIYSIF 292
+ C Y A+P T L +P+++ P PI A D DR I P I+YSI
Sbjct: 248 LVPNTRDCRPLTYQAAIPELRTPEEL-NPIIVTP-PIQAIDQDRNIQPPSDRPGILYSIL 305
Query: 293 RGNVNG---TFIIHPDSGNLTVARSVPSP--MTFLLLVKGQQAD-LARYSVTQVTVEAVA 346
G F +HP + L++ V F L++K +Q + + + +E +
Sbjct: 306 VGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHPLPAFAGLHIEILD 365
Query: 347 AAGSPPRFPQRLYRGTVARGAGAGVVVKDAAAPSQPLRIQAQDPEFSD 394
P F Y+G + A G + D+ + PLRI A D + D
Sbjct: 366 ENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIED 413
Score = 44.7 bits (104), Expect = 4e-04
Identities = 101/420 (24%), Positives = 157/420 (37%), Gaps = 73/420 (17%)
Query: 71 FRIQGN-QLFLNVTPDYEEKSLLEAQLLCQSGGTLV--TQLRVFVSVLDVNDNAPEFPFK 127
FRI N ++ V + E + E ++ G + L + + VLD++DN+P F
Sbjct: 741 FRITSNGSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNS 800
Query: 128 TKEIRVEEDTKVNSTVIPETQLQAEDRDKDDILFYTLQEMTAGASDYFSLVSVNRPALRL 187
T + VEE+ +T++ Q++A+D D + Y ++ +F + L L
Sbjct: 801 TYTVLVEENLPAGTTIL---QIEAKDVDLGANVSYRIRSPEV---KHFFALHPFTGELSL 854
Query: 188 DRPLDFYERP----NMTFWLLVRDTPGENVEPSHTATATLVLNVVPADLRPPWFLPCTFS 243
R LD+ P ++TF + D G P AT T++ V + PP F
Sbjct: 855 LRSLDYEAFPDQEASITFLVEAFDIYG--TMPPGIATVTVI--VKDMNDYPPVF------ 904
Query: 244 DGYVCIQAQYHGAVPTGHILPSPLVLRPGPIYAEDGD-------------RGINQPIIYS 290
+ Y G V + +P+ +YAED D + P S
Sbjct: 905 -----SKRIYKGMVAPDAVKGTPIT----TVYAEDADPPGLPASRVRYRVDDVQFPYPAS 955
Query: 291 IFRGNVNGTFIIHPDSGN-LTVARSVPSPMTFLLLVKGQQADLARYSVTQVTVE-AVAAA 348
IF + DSG +T P T LV D + TV+ V
Sbjct: 956 IFE--------VEEDSGRVITRVNLNEEPTTIFKLVVVAFDDGEPVMSSSATVKILVLHP 1007
Query: 349 GSPPRFPQRLYR-----GTVARGAGAGVVVKDAAAPSQPL---RIQAQDPEFSDLNSAIT 400
G PRF Q YR +G GV+ AAA +Q + + + + +N+
Sbjct: 1008 GEIPRFTQEEYRPPPVSELATKGTMVGVI--SAAAINQSIVYSIVSGNEEDTFGINN--- 1062
Query: 401 YRITNHSHFRMEGEVVLTTTTLAQAGAFYAEVEAHN---TVTSGTATTVIEIQVSEQEPP 457
IT + + T+ + + A EV N S TA IEIQ PP
Sbjct: 1063 --ITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPP 1120
Score = 40.4 bits (93), Expect = 0.007
Identities = 73/383 (19%), Positives = 149/383 (38%), Gaps = 48/383 (12%)
Query: 39 VEENTNVTEPLVDIHVPEGQEVT--------LGALSTPFAFRIQGNQLFLNVTP--DYEE 88
+ ++ N+T PL + + + E T L ++ F G +L + D EE
Sbjct: 392 ISDSLNLTSPLRIVALDKDIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREE 451
Query: 89 KSLLEAQLLCQSGGTLVTQLRVFVSVLDVNDNAPEFPFKTKEIRVEEDTKVNSTVIPETQ 148
+ + G + V + V+D NDN P FP + ++ V D + +VI T
Sbjct: 452 QQTYTFSITAFDGVQESEPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTA 511
Query: 149 LQAEDRDKDDILFYTLQEMTAGASDYFSLVSVNRPALRLDRPLDFYERPNMTFWLLVRDT 208
+ A++ +I + E+ GA F +++ + + ++ T+ L V+
Sbjct: 512 VDADEGSNGEITY----EILVGAQGDF-IINKTTGLITIAPGVEMI--VGRTYALTVQAA 564
Query: 209 PGENVEPSHTATATLVLNVVPADLR-PPWFLPCTFSDGYVCIQAQYHGAVPTGHILPSPL 267
+ T+ + V+P + + PP F +S + A+ G +L +
Sbjct: 565 DNAPPAERRNSICTVYIEVLPPNNQSPPRFPQLMYS-------LEISEAMRVGAVLLN-- 615
Query: 268 VLRPGPIYAEDGDRGINQPIIYSIFRGNVNGTFIIHPDSGNLTVARSVPSPMT--FLLLV 325
+ A D + I Y+I G+ F + +G LT+ +++ T ++L++
Sbjct: 616 ------LQATDRE---GDSITYAIENGDPQRVFNLSETTGILTLGKALDRESTDRYILII 666
Query: 326 KGQQADLARYSVTQVTVEAVAAAGSPPRFPQRLYRGTVARGAGAGVVVKDAAAPSQPLRI 385
S V + + P F L R + V + A + ++
Sbjct: 667 TASDGRPDGTSTATVNIVVTDVNDNAPVFDPYLPR---------NLSVVEEEANAFVGQV 717
Query: 386 QAQDPEFSDLNSAITYRITNHSH 408
+A DP+ + +N + Y + N ++
Sbjct: 718 KATDPD-AGINGQVHYSLGNFNN 739
Score = 32.7 bits (73), Expect = 1.4
Identities = 19/55 (34%), Positives = 25/55 (45%), Gaps = 4/55 (7%)
Query: 713 FDNQAFLPDHKANWAPVPSPTHDPKPAEAPMPAEPAPPGPASPGG----APEPPA 763
F+N A P+ + P+P P P+ P PA APP SP P PP+
Sbjct: 1711 FENFAHPPNISPSACPLPPPPPISPPSPPPAPAPLAPPPDISPFSLFCPPPSPPS 1765
Score = 30.8 bits (68), Expect = 5.5
Identities = 28/88 (31%), Positives = 34/88 (38%), Gaps = 10/88 (11%)
Query: 505 PSGTTLRPPTSSTPGGPPGAENSTSHQP-ATPGGDTAQTPK-PGTSQPMPP----GVGTS 558
PS L PP +P PP A + P +P P P P+PP + S
Sbjct: 1722 PSACPLPPPPPISPPSPPPAPAPLAPPPDISPFSLFCPPPSPPSIPLPLPPPTFFPLSVS 1781
Query: 559 TSHQPATPSGGTAQTPEPGTSQPMPPSM 586
TS P P TP P P PPS+
Sbjct: 1782 TSGPPTPPLLPPFPTPLP----PPPPSI 1805
Score = 30.8 bits (68), Expect = 5.5
Identities = 25/78 (32%), Positives = 33/78 (42%), Gaps = 6/78 (7%)
Query: 451 VSEQEPPSTDVP--PSPEAGGTT---GPWTSTTSEVPRPPEPSQGPSTTSSGGGTGPH-P 504
+S PP P P P+ + P + + +P PP S ++SG T P P
Sbjct: 1733 ISPPSPPPAPAPLAPPPDISPFSLFCPPPSPPSIPLPLPPPTFFPLSVSTSGPPTPPLLP 1792
Query: 505 PSGTTLRPPTSSTPGGPP 522
P T L PP S P PP
Sbjct: 1793 PFPTPLPPPPPSIPCPPP 1810
>gi|218505781 protocadherin 15 isoform CD1-7 precursor [Homo
sapiens]
Length = 1952
Score = 80.1 bits (196), Expect = 8e-15
Identities = 91/348 (26%), Positives = 147/348 (42%), Gaps = 37/348 (10%)
Query: 78 LFLNVT--------PDYEEKSLLEAQLLCQSGGTLVTQLRVFVSVLDVNDNAPEFPFKTK 129
LFLN T P +++ Q + + GT++ V + V D NDN+P F ++
Sbjct: 94 LFLNSTGRVLDRDPPMNIHSIVVQVQCINKKVGTIIYH-EVRIVVRDRNDNSPTFKHESY 152
Query: 130 EIRVEEDTKVNSTVIPETQLQAEDRDKDD--------ILFYTLQEMTAGASDYFSLVSVN 181
V E T V +T+ D DD ++ Y + T+ +D F + +
Sbjct: 153 YATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYNPDDPTS--NDTFEIPLML 210
Query: 182 RPALRLDRPLDFYERPNMTFWLLVRDTPGENVEPSHTATATLVLNVVPADLRPPWFLPCT 241
+ L + L+ YE F ++ + +N+ T T TL ++V+ D P FLPC
Sbjct: 211 TGNIVLRKRLN-YEDKTRYFVIIQANDRAQNLNERRTTTTTLTVDVLDGDDLGPMFLPCV 269
Query: 242 F-SDGYVCIQAQYHGAVP---TGHILPSPLVLRPGPIYAEDGDRGINQP-----IIYSIF 292
+ C Y A+P T L +P+++ P PI A D DR I P I+YSI
Sbjct: 270 LVPNTRDCRPLTYQAAIPELRTPEEL-NPIIVTP-PIQAIDQDRNIQPPSDRPGILYSIL 327
Query: 293 RGNVNG---TFIIHPDSGNLTVARSVPSP--MTFLLLVKGQQAD-LARYSVTQVTVEAVA 346
G F +HP + L++ V F L++K +Q + + + +E +
Sbjct: 328 VGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHPLPAFAGLHIEILD 387
Query: 347 AAGSPPRFPQRLYRGTVARGAGAGVVVKDAAAPSQPLRIQAQDPEFSD 394
P F Y+G + A G + D+ + PLRI A D + D
Sbjct: 388 ENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIED 435
Score = 44.7 bits (104), Expect = 4e-04
Identities = 101/420 (24%), Positives = 157/420 (37%), Gaps = 73/420 (17%)
Query: 71 FRIQGN-QLFLNVTPDYEEKSLLEAQLLCQSGGTLV--TQLRVFVSVLDVNDNAPEFPFK 127
FRI N ++ V + E + E ++ G + L + + VLD++DN+P F
Sbjct: 763 FRITSNGSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNS 822
Query: 128 TKEIRVEEDTKVNSTVIPETQLQAEDRDKDDILFYTLQEMTAGASDYFSLVSVNRPALRL 187
T + VEE+ +T++ Q++A+D D + Y ++ +F + L L
Sbjct: 823 TYTVLVEENLPAGTTIL---QIEAKDVDLGANVSYRIRSPEV---KHFFALHPFTGELSL 876
Query: 188 DRPLDFYERP----NMTFWLLVRDTPGENVEPSHTATATLVLNVVPADLRPPWFLPCTFS 243
R LD+ P ++TF + D G P AT T++ V + PP F
Sbjct: 877 LRSLDYEAFPDQEASITFLVEAFDIYG--TMPPGIATVTVI--VKDMNDYPPVF------ 926
Query: 244 DGYVCIQAQYHGAVPTGHILPSPLVLRPGPIYAEDGD-------------RGINQPIIYS 290
+ Y G V + +P+ +YAED D + P S
Sbjct: 927 -----SKRIYKGMVAPDAVKGTPIT----TVYAEDADPPGLPASRVRYRVDDVQFPYPAS 977
Query: 291 IFRGNVNGTFIIHPDSGN-LTVARSVPSPMTFLLLVKGQQADLARYSVTQVTVE-AVAAA 348
IF + DSG +T P T LV D + TV+ V
Sbjct: 978 IFE--------VEEDSGRVITRVNLNEEPTTIFKLVVVAFDDGEPVMSSSATVKILVLHP 1029
Query: 349 GSPPRFPQRLYR-----GTVARGAGAGVVVKDAAAPSQPL---RIQAQDPEFSDLNSAIT 400
G PRF Q YR +G GV+ AAA +Q + + + + +N+
Sbjct: 1030 GEIPRFTQEEYRPPPVSELATKGTMVGVI--SAAAINQSIVYSIVSGNEEDTFGINN--- 1084
Query: 401 YRITNHSHFRMEGEVVLTTTTLAQAGAFYAEVEAHN---TVTSGTATTVIEIQVSEQEPP 457
IT + + T+ + + A EV N S TA IEIQ PP
Sbjct: 1085 --ITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPP 1142
Score = 40.4 bits (93), Expect = 0.007
Identities = 73/383 (19%), Positives = 149/383 (38%), Gaps = 48/383 (12%)
Query: 39 VEENTNVTEPLVDIHVPEGQEVT--------LGALSTPFAFRIQGNQLFLNVTP--DYEE 88
+ ++ N+T PL + + + E T L ++ F G +L + D EE
Sbjct: 414 ISDSLNLTSPLRIVALDKDIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREE 473
Query: 89 KSLLEAQLLCQSGGTLVTQLRVFVSVLDVNDNAPEFPFKTKEIRVEEDTKVNSTVIPETQ 148
+ + G + V + V+D NDN P FP + ++ V D + +VI T
Sbjct: 474 QQTYTFSITAFDGVQESEPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTA 533
Query: 149 LQAEDRDKDDILFYTLQEMTAGASDYFSLVSVNRPALRLDRPLDFYERPNMTFWLLVRDT 208
+ A++ +I + E+ GA F +++ + + ++ T+ L V+
Sbjct: 534 VDADEGSNGEITY----EILVGAQGDF-IINKTTGLITIAPGVEMI--VGRTYALTVQAA 586
Query: 209 PGENVEPSHTATATLVLNVVPADLR-PPWFLPCTFSDGYVCIQAQYHGAVPTGHILPSPL 267
+ T+ + V+P + + PP F +S + A+ G +L +
Sbjct: 587 DNAPPAERRNSICTVYIEVLPPNNQSPPRFPQLMYS-------LEISEAMRVGAVLLN-- 637
Query: 268 VLRPGPIYAEDGDRGINQPIIYSIFRGNVNGTFIIHPDSGNLTVARSVPSPMT--FLLLV 325
+ A D + I Y+I G+ F + +G LT+ +++ T ++L++
Sbjct: 638 ------LQATDRE---GDSITYAIENGDPQRVFNLSETTGILTLGKALDRESTDRYILII 688
Query: 326 KGQQADLARYSVTQVTVEAVAAAGSPPRFPQRLYRGTVARGAGAGVVVKDAAAPSQPLRI 385
S V + + P F L R + V + A + ++
Sbjct: 689 TASDGRPDGTSTATVNIVVTDVNDNAPVFDPYLPR---------NLSVVEEEANAFVGQV 739
Query: 386 QAQDPEFSDLNSAITYRITNHSH 408
+A DP+ + +N + Y + N ++
Sbjct: 740 KATDPD-AGINGQVHYSLGNFNN 761
Score = 32.7 bits (73), Expect = 1.4
Identities = 19/55 (34%), Positives = 25/55 (45%), Gaps = 4/55 (7%)
Query: 713 FDNQAFLPDHKANWAPVPSPTHDPKPAEAPMPAEPAPPGPASPGG----APEPPA 763
F+N A P+ + P+P P P+ P PA APP SP P PP+
Sbjct: 1728 FENFAHPPNISPSACPLPPPPPISPPSPPPAPAPLAPPPDISPFSLFCPPPSPPS 1782
Score = 30.8 bits (68), Expect = 5.5
Identities = 28/88 (31%), Positives = 34/88 (38%), Gaps = 10/88 (11%)
Query: 505 PSGTTLRPPTSSTPGGPPGAENSTSHQP-ATPGGDTAQTPK-PGTSQPMPP----GVGTS 558
PS L PP +P PP A + P +P P P P+PP + S
Sbjct: 1739 PSACPLPPPPPISPPSPPPAPAPLAPPPDISPFSLFCPPPSPPSIPLPLPPPTFFPLSVS 1798
Query: 559 TSHQPATPSGGTAQTPEPGTSQPMPPSM 586
TS P P TP P P PPS+
Sbjct: 1799 TSGPPTPPLLPPFPTPLP----PPPPSI 1822
Score = 30.8 bits (68), Expect = 5.5
Identities = 25/78 (32%), Positives = 33/78 (42%), Gaps = 6/78 (7%)
Query: 451 VSEQEPPSTDVP--PSPEAGGTT---GPWTSTTSEVPRPPEPSQGPSTTSSGGGTGPH-P 504
+S PP P P P+ + P + + +P PP S ++SG T P P
Sbjct: 1750 ISPPSPPPAPAPLAPPPDISPFSLFCPPPSPPSIPLPLPPPTFFPLSVSTSGPPTPPLLP 1809
Query: 505 PSGTTLRPPTSSTPGGPP 522
P T L PP S P PP
Sbjct: 1810 PFPTPLPPPPPSIPCPPP 1827
>gi|218505779 protocadherin 15 isoform CD1-6 precursor [Homo
sapiens]
Length = 1886
Score = 80.1 bits (196), Expect = 8e-15
Identities = 91/348 (26%), Positives = 147/348 (42%), Gaps = 37/348 (10%)
Query: 78 LFLNVT--------PDYEEKSLLEAQLLCQSGGTLVTQLRVFVSVLDVNDNAPEFPFKTK 129
LFLN T P +++ Q + + GT++ V + V D NDN+P F ++
Sbjct: 94 LFLNSTGRVLDRDPPMNIHSIVVQVQCINKKVGTIIYH-EVRIVVRDRNDNSPTFKHESY 152
Query: 130 EIRVEEDTKVNSTVIPETQLQAEDRDKDD--------ILFYTLQEMTAGASDYFSLVSVN 181
V E T V +T+ D DD ++ Y + T+ +D F + +
Sbjct: 153 YATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYNPDDPTS--NDTFEIPLML 210
Query: 182 RPALRLDRPLDFYERPNMTFWLLVRDTPGENVEPSHTATATLVLNVVPADLRPPWFLPCT 241
+ L + L+ YE F ++ + +N+ T T TL ++V+ D P FLPC
Sbjct: 211 TGNIVLRKRLN-YEDKTRYFVIIQANDRAQNLNERRTTTTTLTVDVLDGDDLGPMFLPCV 269
Query: 242 F-SDGYVCIQAQYHGAVP---TGHILPSPLVLRPGPIYAEDGDRGINQP-----IIYSIF 292
+ C Y A+P T L +P+++ P PI A D DR I P I+YSI
Sbjct: 270 LVPNTRDCRPLTYQAAIPELRTPEEL-NPIIVTP-PIQAIDQDRNIQPPSDRPGILYSIL 327
Query: 293 RGNVNG---TFIIHPDSGNLTVARSVPSP--MTFLLLVKGQQAD-LARYSVTQVTVEAVA 346
G F +HP + L++ V F L++K +Q + + + +E +
Sbjct: 328 VGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHPLPAFAGLHIEILD 387
Query: 347 AAGSPPRFPQRLYRGTVARGAGAGVVVKDAAAPSQPLRIQAQDPEFSD 394
P F Y+G + A G + D+ + PLRI A D + D
Sbjct: 388 ENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIED 435
Score = 58.5 bits (140), Expect = 2e-08
Identities = 87/305 (28%), Positives = 136/305 (44%), Gaps = 57/305 (18%)
Query: 110 VFVSVLDVNDNAPEF-PFKTKEIRVEEDTKVNSTVIPETQLQAEDRDK--DDILFYTLQE 166
V + V DVNDNAP F P+ + + V E+ + N+ V Q++A D D + + Y+L
Sbjct: 632 VNIVVTDVNDNAPVFDPYLPRNLSVVEE-EANAFV---GQVKATDPDAGINGQVHYSL-- 685
Query: 167 MTAGASDYFSLVSVNR--PALRLDRPL-DFYERPNMTFWLLVRDTPGENVEPSHTATATL 223
++ F + S A++L+R + D+YE L+V T G V P H +T TL
Sbjct: 686 --GNFNNLFRITSNGSIYTAVKLNREVRDYYE-------LVVVATDGA-VHPRH-STLTL 734
Query: 224 VLNVVPADLRPPWFLPCTFSDGYVCIQAQYHGAVPTGHILPSPLVLRPGPIYAEDGDRGI 283
+ V+ D P F T++ V ++ +P G + I A+D D G
Sbjct: 735 AIKVLDIDDNSPVFTNSTYT---VLVEEN----LPAGTTILQ--------IEAKDVDLGA 779
Query: 284 NQPIIYSIFRGNVNGTFIIHPDSGNLTVARSV--------PSPMTFLLLVKGQQADLARY 335
N + Y I V F +HP +G L++ RS+ + +TFL+ +
Sbjct: 780 N--VSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPP- 836
Query: 336 SVTQVTVEAVAAAGSPPRFPQRLYRGTVARGAGAG-----VVVKDAAAPSQP---LRIQA 387
+ VTV PP F +R+Y+G VA A G V +DA P P +R +
Sbjct: 837 GIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPPGLPASRVRYRV 896
Query: 388 QDPEF 392
D +F
Sbjct: 897 DDVQF 901
Score = 53.1 bits (126), Expect = 1e-06
Identities = 100/463 (21%), Positives = 176/463 (38%), Gaps = 67/463 (14%)
Query: 39 VEENTNVTEPLVDIHVPEGQEVT--------LGALSTPFAFRIQGNQLFLNVTP--DYEE 88
+ ++ N+T PL + + + E T L ++ F G +L + D EE
Sbjct: 414 ISDSLNLTSPLRIVALDKDIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREE 473
Query: 89 KSLLEAQLLCQSGGTLVTQLRVFVSVLDVNDNAPEFPFKTKEIRVEEDTKVNSTVIPETQ 148
+ + G + V + V+D NDN P FP + ++ V D + +VI T
Sbjct: 474 QQTYTFSITAFDGVQESEPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTA 533
Query: 149 LQAEDRDKDDILFYTLQEMTAGASDYFSLVSVNRPALRLDRPLDFYERPNMTFWLLVRDT 208
+ A++ +I + E+ GA F +++ + + ++ T+ L V+
Sbjct: 534 VDADEGSNGEITY----EILVGAQGDF-IINKTTGLITIAPGVEMI--VGRTYALTVQ-- 584
Query: 209 PGENVEPSHTATATLVL-NVVPADLRPPWFLPCTFSDG----------YVCIQAQYHGAV 257
+N P+ +T L L + + + L T SDG + + A
Sbjct: 585 AADNAPPAERSTGILTLGKALDRESTDRYILIITASDGRPDGTSTATVNIVVTDVNDNAP 644
Query: 258 PTGHILPSPLVLRP-------GPIYAEDGDRGINQPIIYSIFRGNVNGTFIIHPDSGNLT 310
LP L + G + A D D GIN + YS+ GN N F I + T
Sbjct: 645 VFDPYLPRNLSVVEEEANAFVGQVKATDPDAGINGQVHYSL--GNFNNLFRITSNGSIYT 702
Query: 311 VARSVPSPMTF--LLLVKGQQADLARYSVTQVTVEAVAAAGSPPRFPQRLYRGTVARGAG 368
+ + L++V A R+S + ++ + + P F Y V
Sbjct: 703 AVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLP 762
Query: 369 AGVVVKDAAAPSQPLRIQAQDPEFSDLNSAITYRITNH--SHF----RMEGEVVLTTTTL 422
AG + L+I+A+D DL + ++YRI + HF GE+ L +
Sbjct: 763 AGTTI---------LQIEAKD---VDLGANVSYRIRSPEVKHFFALHPFTGELSLLRSLD 810
Query: 423 AQAG-------AFYAEV-EAHNTVTSGTATTVIEIQVSEQEPP 457
+A F E + + T+ G AT + ++ PP
Sbjct: 811 YEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPP 853
Score = 44.7 bits (104), Expect = 4e-04
Identities = 101/420 (24%), Positives = 157/420 (37%), Gaps = 73/420 (17%)
Query: 71 FRIQGN-QLFLNVTPDYEEKSLLEAQLLCQSGGTLV--TQLRVFVSVLDVNDNAPEFPFK 127
FRI N ++ V + E + E ++ G + L + + VLD++DN+P F
Sbjct: 692 FRITSNGSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNS 751
Query: 128 TKEIRVEEDTKVNSTVIPETQLQAEDRDKDDILFYTLQEMTAGASDYFSLVSVNRPALRL 187
T + VEE+ +T++ Q++A+D D + Y ++ +F + L L
Sbjct: 752 TYTVLVEENLPAGTTIL---QIEAKDVDLGANVSYRIRSPEV---KHFFALHPFTGELSL 805
Query: 188 DRPLDFYERP----NMTFWLLVRDTPGENVEPSHTATATLVLNVVPADLRPPWFLPCTFS 243
R LD+ P ++TF + D G P AT T++ V + PP F
Sbjct: 806 LRSLDYEAFPDQEASITFLVEAFDIYG--TMPPGIATVTVI--VKDMNDYPPVF------ 855
Query: 244 DGYVCIQAQYHGAVPTGHILPSPLVLRPGPIYAEDGD-------------RGINQPIIYS 290
+ Y G V + +P+ +YAED D + P S
Sbjct: 856 -----SKRIYKGMVAPDAVKGTPIT----TVYAEDADPPGLPASRVRYRVDDVQFPYPAS 906
Query: 291 IFRGNVNGTFIIHPDSGN-LTVARSVPSPMTFLLLVKGQQADLARYSVTQVTVE-AVAAA 348
IF + DSG +T P T LV D + TV+ V
Sbjct: 907 IFE--------VEEDSGRVITRVNLNEEPTTIFKLVVVAFDDGEPVMSSSATVKILVLHP 958
Query: 349 GSPPRFPQRLYR-----GTVARGAGAGVVVKDAAAPSQPL---RIQAQDPEFSDLNSAIT 400
G PRF Q YR +G GV+ AAA +Q + + + + +N+
Sbjct: 959 GEIPRFTQEEYRPPPVSELATKGTMVGVI--SAAAINQSIVYSIVSGNEEDTFGINN--- 1013
Query: 401 YRITNHSHFRMEGEVVLTTTTLAQAGAFYAEVEAHN---TVTSGTATTVIEIQVSEQEPP 457
IT + + T+ + + A EV N S TA IEIQ PP
Sbjct: 1014 --ITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPP 1071
Score = 32.7 bits (73), Expect = 1.4
Identities = 19/55 (34%), Positives = 25/55 (45%), Gaps = 4/55 (7%)
Query: 713 FDNQAFLPDHKANWAPVPSPTHDPKPAEAPMPAEPAPPGPASPGG----APEPPA 763
F+N A P+ + P+P P P+ P PA APP SP P PP+
Sbjct: 1662 FENFAHPPNISPSACPLPPPPPISPPSPPPAPAPLAPPPDISPFSLFCPPPSPPS 1716
Score = 30.8 bits (68), Expect = 5.5
Identities = 28/88 (31%), Positives = 34/88 (38%), Gaps = 10/88 (11%)
Query: 505 PSGTTLRPPTSSTPGGPPGAENSTSHQP-ATPGGDTAQTPK-PGTSQPMPP----GVGTS 558
PS L PP +P PP A + P +P P P P+PP + S
Sbjct: 1673 PSACPLPPPPPISPPSPPPAPAPLAPPPDISPFSLFCPPPSPPSIPLPLPPPTFFPLSVS 1732
Query: 559 TSHQPATPSGGTAQTPEPGTSQPMPPSM 586
TS P P TP P P PPS+
Sbjct: 1733 TSGPPTPPLLPPFPTPLP----PPPPSI 1756
Score = 30.8 bits (68), Expect = 5.5
Identities = 25/78 (32%), Positives = 33/78 (42%), Gaps = 6/78 (7%)
Query: 451 VSEQEPPSTDVP--PSPEAGGTT---GPWTSTTSEVPRPPEPSQGPSTTSSGGGTGPH-P 504
+S PP P P P+ + P + + +P PP S ++SG T P P
Sbjct: 1684 ISPPSPPPAPAPLAPPPDISPFSLFCPPPSPPSIPLPLPPPTFFPLSVSTSGPPTPPLLP 1743
Query: 505 PSGTTLRPPTSSTPGGPP 522
P T L PP S P PP
Sbjct: 1744 PFPTPLPPPPPSIPCPPP 1761
>gi|218505777 protocadherin 15 isoform CD1-2 precursor [Homo
sapiens]
Length = 1957
Score = 80.1 bits (196), Expect = 8e-15
Identities = 91/348 (26%), Positives = 147/348 (42%), Gaps = 37/348 (10%)
Query: 78 LFLNVT--------PDYEEKSLLEAQLLCQSGGTLVTQLRVFVSVLDVNDNAPEFPFKTK 129
LFLN T P +++ Q + + GT++ V + V D NDN+P F ++
Sbjct: 94 LFLNSTGRVLDRDPPMNIHSIVVQVQCINKKVGTIIYH-EVRIVVRDRNDNSPTFKHESY 152
Query: 130 EIRVEEDTKVNSTVIPETQLQAEDRDKDD--------ILFYTLQEMTAGASDYFSLVSVN 181
V E T V +T+ D DD ++ Y + T+ +D F + +
Sbjct: 153 YATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYNPDDPTS--NDTFEIPLML 210
Query: 182 RPALRLDRPLDFYERPNMTFWLLVRDTPGENVEPSHTATATLVLNVVPADLRPPWFLPCT 241
+ L + L+ YE F ++ + +N+ T T TL ++V+ D P FLPC
Sbjct: 211 TGNIVLRKRLN-YEDKTRYFVIIQANDRAQNLNERRTTTTTLTVDVLDGDDLGPMFLPCV 269
Query: 242 F-SDGYVCIQAQYHGAVP---TGHILPSPLVLRPGPIYAEDGDRGINQP-----IIYSIF 292
+ C Y A+P T L +P+++ P PI A D DR I P I+YSI
Sbjct: 270 LVPNTRDCRPLTYQAAIPELRTPEEL-NPIIVTP-PIQAIDQDRNIQPPSDRPGILYSIL 327
Query: 293 RGNVNG---TFIIHPDSGNLTVARSVPSP--MTFLLLVKGQQAD-LARYSVTQVTVEAVA 346
G F +HP + L++ V F L++K +Q + + + +E +
Sbjct: 328 VGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHPLPAFAGLHIEILD 387
Query: 347 AAGSPPRFPQRLYRGTVARGAGAGVVVKDAAAPSQPLRIQAQDPEFSD 394
P F Y+G + A G + D+ + PLRI A D + D
Sbjct: 388 ENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIED 435
Score = 44.7 bits (104), Expect = 4e-04
Identities = 101/420 (24%), Positives = 157/420 (37%), Gaps = 73/420 (17%)
Query: 71 FRIQGN-QLFLNVTPDYEEKSLLEAQLLCQSGGTLV--TQLRVFVSVLDVNDNAPEFPFK 127
FRI N ++ V + E + E ++ G + L + + VLD++DN+P F
Sbjct: 763 FRITSNGSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNS 822
Query: 128 TKEIRVEEDTKVNSTVIPETQLQAEDRDKDDILFYTLQEMTAGASDYFSLVSVNRPALRL 187
T + VEE+ +T++ Q++A+D D + Y ++ +F + L L
Sbjct: 823 TYTVLVEENLPAGTTIL---QIEAKDVDLGANVSYRIRSPEV---KHFFALHPFTGELSL 876
Query: 188 DRPLDFYERP----NMTFWLLVRDTPGENVEPSHTATATLVLNVVPADLRPPWFLPCTFS 243
R LD+ P ++TF + D G P AT T++ V + PP F
Sbjct: 877 LRSLDYEAFPDQEASITFLVEAFDIYG--TMPPGIATVTVI--VKDMNDYPPVF------ 926
Query: 244 DGYVCIQAQYHGAVPTGHILPSPLVLRPGPIYAEDGD-------------RGINQPIIYS 290
+ Y G V + +P+ +YAED D + P S
Sbjct: 927 -----SKRIYKGMVAPDAVKGTPIT----TVYAEDADPPGLPASRVRYRVDDVQFPYPAS 977
Query: 291 IFRGNVNGTFIIHPDSGN-LTVARSVPSPMTFLLLVKGQQADLARYSVTQVTVE-AVAAA 348
IF + DSG +T P T LV D + TV+ V
Sbjct: 978 IFE--------VEEDSGRVITRVNLNEEPTTIFKLVVVAFDDGEPVMSSSATVKILVLHP 1029
Query: 349 GSPPRFPQRLYR-----GTVARGAGAGVVVKDAAAPSQPL---RIQAQDPEFSDLNSAIT 400
G PRF Q YR +G GV+ AAA +Q + + + + +N+
Sbjct: 1030 GEIPRFTQEEYRPPPVSELATKGTMVGVI--SAAAINQSIVYSIVSGNEEDTFGINN--- 1084
Query: 401 YRITNHSHFRMEGEVVLTTTTLAQAGAFYAEVEAHN---TVTSGTATTVIEIQVSEQEPP 457
IT + + T+ + + A EV N S TA IEIQ PP
Sbjct: 1085 --ITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPP 1142
Score = 40.4 bits (93), Expect = 0.007
Identities = 73/383 (19%), Positives = 149/383 (38%), Gaps = 48/383 (12%)
Query: 39 VEENTNVTEPLVDIHVPEGQEVT--------LGALSTPFAFRIQGNQLFLNVTP--DYEE 88
+ ++ N+T PL + + + E T L ++ F G +L + D EE
Sbjct: 414 ISDSLNLTSPLRIVALDKDIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREE 473
Query: 89 KSLLEAQLLCQSGGTLVTQLRVFVSVLDVNDNAPEFPFKTKEIRVEEDTKVNSTVIPETQ 148
+ + G + V + V+D NDN P FP + ++ V D + +VI T
Sbjct: 474 QQTYTFSITAFDGVQESEPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTA 533
Query: 149 LQAEDRDKDDILFYTLQEMTAGASDYFSLVSVNRPALRLDRPLDFYERPNMTFWLLVRDT 208
+ A++ +I + E+ GA F +++ + + ++ T+ L V+
Sbjct: 534 VDADEGSNGEITY----EILVGAQGDF-IINKTTGLITIAPGVEMI--VGRTYALTVQAA 586
Query: 209 PGENVEPSHTATATLVLNVVPADLR-PPWFLPCTFSDGYVCIQAQYHGAVPTGHILPSPL 267
+ T+ + V+P + + PP F +S + A+ G +L +
Sbjct: 587 DNAPPAERRNSICTVYIEVLPPNNQSPPRFPQLMYS-------LEISEAMRVGAVLLN-- 637
Query: 268 VLRPGPIYAEDGDRGINQPIIYSIFRGNVNGTFIIHPDSGNLTVARSVPSPMT--FLLLV 325
+ A D + I Y+I G+ F + +G LT+ +++ T ++L++
Sbjct: 638 ------LQATDRE---GDSITYAIENGDPQRVFNLSETTGILTLGKALDRESTDRYILII 688
Query: 326 KGQQADLARYSVTQVTVEAVAAAGSPPRFPQRLYRGTVARGAGAGVVVKDAAAPSQPLRI 385
S V + + P F L R + V + A + ++
Sbjct: 689 TASDGRPDGTSTATVNIVVTDVNDNAPVFDPYLPR---------NLSVVEEEANAFVGQV 739
Query: 386 QAQDPEFSDLNSAITYRITNHSH 408
+A DP+ + +N + Y + N ++
Sbjct: 740 KATDPD-AGINGQVHYSLGNFNN 761
Score = 32.7 bits (73), Expect = 1.4
Identities = 19/55 (34%), Positives = 25/55 (45%), Gaps = 4/55 (7%)
Query: 713 FDNQAFLPDHKANWAPVPSPTHDPKPAEAPMPAEPAPPGPASPGG----APEPPA 763
F+N A P+ + P+P P P+ P PA APP SP P PP+
Sbjct: 1733 FENFAHPPNISPSACPLPPPPPISPPSPPPAPAPLAPPPDISPFSLFCPPPSPPS 1787
Score = 30.8 bits (68), Expect = 5.5
Identities = 28/88 (31%), Positives = 34/88 (38%), Gaps = 10/88 (11%)
Query: 505 PSGTTLRPPTSSTPGGPPGAENSTSHQP-ATPGGDTAQTPK-PGTSQPMPP----GVGTS 558
PS L PP +P PP A + P +P P P P+PP + S
Sbjct: 1744 PSACPLPPPPPISPPSPPPAPAPLAPPPDISPFSLFCPPPSPPSIPLPLPPPTFFPLSVS 1803
Query: 559 TSHQPATPSGGTAQTPEPGTSQPMPPSM 586
TS P P TP P P PPS+
Sbjct: 1804 TSGPPTPPLLPPFPTPLP----PPPPSI 1827
Score = 30.8 bits (68), Expect = 5.5
Identities = 25/78 (32%), Positives = 33/78 (42%), Gaps = 6/78 (7%)
Query: 451 VSEQEPPSTDVP--PSPEAGGTT---GPWTSTTSEVPRPPEPSQGPSTTSSGGGTGPH-P 504
+S PP P P P+ + P + + +P PP S ++SG T P P
Sbjct: 1755 ISPPSPPPAPAPLAPPPDISPFSLFCPPPSPPSIPLPLPPPTFFPLSVSTSGPPTPPLLP 1814
Query: 505 PSGTTLRPPTSSTPGGPP 522
P T L PP S P PP
Sbjct: 1815 PFPTPLPPPPPSIPCPPP 1832
>gi|218505775 protocadherin 15 isoform CD1-1 precursor [Homo
sapiens]
Length = 1962
Score = 80.1 bits (196), Expect = 8e-15
Identities = 91/348 (26%), Positives = 147/348 (42%), Gaps = 37/348 (10%)
Query: 78 LFLNVT--------PDYEEKSLLEAQLLCQSGGTLVTQLRVFVSVLDVNDNAPEFPFKTK 129
LFLN T P +++ Q + + GT++ V + V D NDN+P F ++
Sbjct: 99 LFLNSTGRVLDRDPPMNIHSIVVQVQCINKKVGTIIYH-EVRIVVRDRNDNSPTFKHESY 157
Query: 130 EIRVEEDTKVNSTVIPETQLQAEDRDKDD--------ILFYTLQEMTAGASDYFSLVSVN 181
V E T V +T+ D DD ++ Y + T+ +D F + +
Sbjct: 158 YATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYNPDDPTS--NDTFEIPLML 215
Query: 182 RPALRLDRPLDFYERPNMTFWLLVRDTPGENVEPSHTATATLVLNVVPADLRPPWFLPCT 241
+ L + L+ YE F ++ + +N+ T T TL ++V+ D P FLPC
Sbjct: 216 TGNIVLRKRLN-YEDKTRYFVIIQANDRAQNLNERRTTTTTLTVDVLDGDDLGPMFLPCV 274
Query: 242 F-SDGYVCIQAQYHGAVP---TGHILPSPLVLRPGPIYAEDGDRGINQP-----IIYSIF 292
+ C Y A+P T L +P+++ P PI A D DR I P I+YSI
Sbjct: 275 LVPNTRDCRPLTYQAAIPELRTPEEL-NPIIVTP-PIQAIDQDRNIQPPSDRPGILYSIL 332
Query: 293 RGNVNG---TFIIHPDSGNLTVARSVPSP--MTFLLLVKGQQAD-LARYSVTQVTVEAVA 346
G F +HP + L++ V F L++K +Q + + + +E +
Sbjct: 333 VGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHPLPAFAGLHIEILD 392
Query: 347 AAGSPPRFPQRLYRGTVARGAGAGVVVKDAAAPSQPLRIQAQDPEFSD 394
P F Y+G + A G + D+ + PLRI A D + D
Sbjct: 393 ENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIED 440
Score = 44.7 bits (104), Expect = 4e-04
Identities = 101/420 (24%), Positives = 157/420 (37%), Gaps = 73/420 (17%)
Query: 71 FRIQGN-QLFLNVTPDYEEKSLLEAQLLCQSGGTLV--TQLRVFVSVLDVNDNAPEFPFK 127
FRI N ++ V + E + E ++ G + L + + VLD++DN+P F
Sbjct: 768 FRITSNGSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNS 827
Query: 128 TKEIRVEEDTKVNSTVIPETQLQAEDRDKDDILFYTLQEMTAGASDYFSLVSVNRPALRL 187
T + VEE+ +T++ Q++A+D D + Y ++ +F + L L
Sbjct: 828 TYTVLVEENLPAGTTIL---QIEAKDVDLGANVSYRIRSPEV---KHFFALHPFTGELSL 881
Query: 188 DRPLDFYERP----NMTFWLLVRDTPGENVEPSHTATATLVLNVVPADLRPPWFLPCTFS 243
R LD+ P ++TF + D G P AT T++ V + PP F
Sbjct: 882 LRSLDYEAFPDQEASITFLVEAFDIYG--TMPPGIATVTVI--VKDMNDYPPVF------ 931
Query: 244 DGYVCIQAQYHGAVPTGHILPSPLVLRPGPIYAEDGD-------------RGINQPIIYS 290
+ Y G V + +P+ +YAED D + P S
Sbjct: 932 -----SKRIYKGMVAPDAVKGTPIT----TVYAEDADPPGLPASRVRYRVDDVQFPYPAS 982
Query: 291 IFRGNVNGTFIIHPDSGN-LTVARSVPSPMTFLLLVKGQQADLARYSVTQVTVE-AVAAA 348
IF + DSG +T P T LV D + TV+ V
Sbjct: 983 IFE--------VEEDSGRVITRVNLNEEPTTIFKLVVVAFDDGEPVMSSSATVKILVLHP 1034
Query: 349 GSPPRFPQRLYR-----GTVARGAGAGVVVKDAAAPSQPL---RIQAQDPEFSDLNSAIT 400
G PRF Q YR +G GV+ AAA +Q + + + + +N+
Sbjct: 1035 GEIPRFTQEEYRPPPVSELATKGTMVGVI--SAAAINQSIVYSIVSGNEEDTFGINN--- 1089
Query: 401 YRITNHSHFRMEGEVVLTTTTLAQAGAFYAEVEAHN---TVTSGTATTVIEIQVSEQEPP 457
IT + + T+ + + A EV N S TA IEIQ PP
Sbjct: 1090 --ITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPP 1147
Score = 40.4 bits (93), Expect = 0.007
Identities = 73/383 (19%), Positives = 149/383 (38%), Gaps = 48/383 (12%)
Query: 39 VEENTNVTEPLVDIHVPEGQEVT--------LGALSTPFAFRIQGNQLFLNVTP--DYEE 88
+ ++ N+T PL + + + E T L ++ F G +L + D EE
Sbjct: 419 ISDSLNLTSPLRIVALDKDIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREE 478
Query: 89 KSLLEAQLLCQSGGTLVTQLRVFVSVLDVNDNAPEFPFKTKEIRVEEDTKVNSTVIPETQ 148
+ + G + V + V+D NDN P FP + ++ V D + +VI T
Sbjct: 479 QQTYTFSITAFDGVQESEPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTA 538
Query: 149 LQAEDRDKDDILFYTLQEMTAGASDYFSLVSVNRPALRLDRPLDFYERPNMTFWLLVRDT 208
+ A++ +I + E+ GA F +++ + + ++ T+ L V+
Sbjct: 539 VDADEGSNGEITY----EILVGAQGDF-IINKTTGLITIAPGVEMI--VGRTYALTVQAA 591
Query: 209 PGENVEPSHTATATLVLNVVPADLR-PPWFLPCTFSDGYVCIQAQYHGAVPTGHILPSPL 267
+ T+ + V+P + + PP F +S + A+ G +L +
Sbjct: 592 DNAPPAERRNSICTVYIEVLPPNNQSPPRFPQLMYS-------LEISEAMRVGAVLLN-- 642
Query: 268 VLRPGPIYAEDGDRGINQPIIYSIFRGNVNGTFIIHPDSGNLTVARSVPSPMT--FLLLV 325
+ A D + I Y+I G+ F + +G LT+ +++ T ++L++
Sbjct: 643 ------LQATDRE---GDSITYAIENGDPQRVFNLSETTGILTLGKALDRESTDRYILII 693
Query: 326 KGQQADLARYSVTQVTVEAVAAAGSPPRFPQRLYRGTVARGAGAGVVVKDAAAPSQPLRI 385
S V + + P F L R + V + A + ++
Sbjct: 694 TASDGRPDGTSTATVNIVVTDVNDNAPVFDPYLPR---------NLSVVEEEANAFVGQV 744
Query: 386 QAQDPEFSDLNSAITYRITNHSH 408
+A DP+ + +N + Y + N ++
Sbjct: 745 KATDPD-AGINGQVHYSLGNFNN 766
Score = 32.7 bits (73), Expect = 1.4
Identities = 19/55 (34%), Positives = 25/55 (45%), Gaps = 4/55 (7%)
Query: 713 FDNQAFLPDHKANWAPVPSPTHDPKPAEAPMPAEPAPPGPASPGG----APEPPA 763
F+N A P+ + P+P P P+ P PA APP SP P PP+
Sbjct: 1738 FENFAHPPNISPSACPLPPPPPISPPSPPPAPAPLAPPPDISPFSLFCPPPSPPS 1792
Score = 30.8 bits (68), Expect = 5.5
Identities = 28/88 (31%), Positives = 34/88 (38%), Gaps = 10/88 (11%)
Query: 505 PSGTTLRPPTSSTPGGPPGAENSTSHQP-ATPGGDTAQTPK-PGTSQPMPP----GVGTS 558
PS L PP +P PP A + P +P P P P+PP + S
Sbjct: 1749 PSACPLPPPPPISPPSPPPAPAPLAPPPDISPFSLFCPPPSPPSIPLPLPPPTFFPLSVS 1808
Query: 559 TSHQPATPSGGTAQTPEPGTSQPMPPSM 586
TS P P TP P P PPS+
Sbjct: 1809 TSGPPTPPLLPPFPTPLP----PPPPSI 1832
Score = 30.8 bits (68), Expect = 5.5
Identities = 25/78 (32%), Positives = 33/78 (42%), Gaps = 6/78 (7%)
Query: 451 VSEQEPPSTDVP--PSPEAGGTT---GPWTSTTSEVPRPPEPSQGPSTTSSGGGTGPH-P 504
+S PP P P P+ + P + + +P PP S ++SG T P P
Sbjct: 1760 ISPPSPPPAPAPLAPPPDISPFSLFCPPPSPPSIPLPLPPPTFFPLSVSTSGPPTPPLLP 1819
Query: 505 PSGTTLRPPTSSTPGGPP 522
P T L PP S P PP
Sbjct: 1820 PFPTPLPPPPPSIPCPPP 1837
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 79.7 bits (195), Expect = 1e-14
Identities = 99/360 (27%), Positives = 129/360 (35%), Gaps = 42/360 (11%)
Query: 434 AHNTVTSGTATTVIEIQVSEQEP-PSTDVPPSPEAGGTTGPWTSTTSEVPRPPEPSQ-GP 491
A T T TT E + +EP P+T P+P A P TT + P P P + P
Sbjct: 318 APTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP---TTPKEPAPTTPKEPAP 374
Query: 492 STTSSGGGTGPHPPSGTTLRPP-----------TSSTPGGPPGAENSTSHQPA--TPGGD 538
+TT T P P+ TT + T S P P +T+ +PA TP
Sbjct: 375 TTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP 434
Query: 539 TAQTPK-PGTSQPMPPGVGTSTSHQPATPSGGTAQTPEPGTSQPMPPSMGTSTSHQPATP 597
TPK P + P P T P P+ T + P P T P P+ T P TP
Sbjct: 435 APTTPKKPAPTTPKEPAPTT-----PKEPAPTTTKKPAPTT--PKEPAPTTPKETAPTTP 487
Query: 598 GGGTAQTPE-AGTSQPMPPGMGTSTSHQPTTPGGGTAQTP-EPGTSQPMPLSKSTPSSGG 655
T TPE + P P T PTTP T TP EP + P + +TP
Sbjct: 488 KKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA 547
Query: 656 GPSEDKRFSVVDMAALGGVLGALLLLALLGLAVLVHKHYGPRLKCCSGKAPEPQPQGFDN 715
+ + G A K P + K P P+
Sbjct: 548 PTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAP----TTPKKPAPKELA--- 600
Query: 716 QAFLPDHKANWAPVPSPTHDPKPAEAPMPAEPAPPGPASPGGAPEPPAAARAGGSPTAVR 775
+ + P+PT PK P EPAP P P AP P G +PT ++
Sbjct: 601 PTTTKEPTSTTCDKPAPT-TPKGTAPTTPKEPAPTTPKEP--APTTP----KGTAPTTLK 653
Score = 78.6 bits (192), Expect = 2e-14
Identities = 101/379 (26%), Positives = 134/379 (35%), Gaps = 26/379 (6%)
Query: 420 TTLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPSTDVPPSPEAGGTTGPWTSTTS 479
TT + + A T S TT + + P+T PSP TT TT
Sbjct: 375 TTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPT---TTKEPAPTTP 431
Query: 480 EVPRPPEPSQ-GPSTTSSGGGTGPHPPSGTTLRPPTSSTPGGP-PGAENSTSHQPATPGG 537
+ P P P + P+T T P P+ TT + P +TP P P T+ P TP
Sbjct: 432 KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA--PTTPKK 489
Query: 538 DTAQTP-KPGTSQPMPPGVGTSTSHQPATPSGGTAQTPEPGTSQPMPPSMGTSTSHQPAT 596
T TP K + P P T P TP T TPE +P P + + + P
Sbjct: 490 LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPE----EPAPTTPKAAAPNTPKE 545
Query: 597 PGGGTAQTPEAGTSQPMPPGMGTSTSHQPTTPGGG---TAQTPEPGTSQ---PMPLSKST 650
P T + P T P P T PTTP G T + P P T + P L+ +T
Sbjct: 546 PAPTTPKEPAPTT--PKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 603
Query: 651 PSSGGGPSEDKRFSVVDMAALGGVLGALLLLALLGLAVLVHKHYGPR-LKCCSGKAPE-P 708
+ DK A K P LK + P+ P
Sbjct: 604 TKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKP 663
Query: 709 QPQGFDNQAFLPDHKANWAPVPSPTHDPKPAEAPMPAEPAPPGPASPG-GAPE-PPAAAR 766
P+ + + P+PT PK P EPAP P P PE PP
Sbjct: 664 APKELAPTT-TKGPTSTTSDKPAPT-TPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTS 721
Query: 767 AGGSPTAVRSILTKERRPE 785
+PT + T + P+
Sbjct: 722 EVSTPTTTKEPTTIHKSPD 740
Score = 78.2 bits (191), Expect = 3e-14
Identities = 96/374 (25%), Positives = 129/374 (34%), Gaps = 52/374 (13%)
Query: 418 TTTTLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPSTDV--PPSPEAGGTTGPWT 475
TTTT Q + TS T IE ++ P++ V P+P+A TT
Sbjct: 155 TTTTNKQTST-----DGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPA 209
Query: 476 STTSEVPRPPEPSQGPSTTSSGGGTGPHPPSGTTLRPPTSSTPGGPPGAENSTSHQPATP 535
TT + P P P + STT P P+ TT++ ++ P S P P
Sbjct: 210 LTTPKEPTPTTPKEPASTT-------PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEP 262
Query: 536 GGDTAQTPKPGTSQPMPPGVGTSTSHQPATPSGGTAQTPEPGTSQPMPPSMGTSTSHQPA 595
T + P P T P P T+ P T EP + P P+ T P
Sbjct: 263 APTTTKEPAPTT--PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPT 320
Query: 596 TPGGGTAQTPEAG---TSQPMPPGMGTSTSHQPTTPGGGTAQTPEPGT-SQPMPLSKSTP 651
TP T TP+ T +P P P P T + P P T +P P + P
Sbjct: 321 TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEP 380
Query: 652 SSGGGPSEDKRFSVVDMAALGGVLGALLLLALLGLAVLVHKHYGPRLKCCSGKAP-EPQP 710
S P+ K + + A K P + P EP P
Sbjct: 381 S----PTTPKEPAPTTTKS----------------APTTTKEPAPTTTKSAPTTPKEPSP 420
Query: 711 QGFDNQA-FLPDHKANWAP-VPSPTHDPKPAEAPMPAEPAP-----PGPASPGGAPEPPA 763
A P A P P+PT +PA P EPAP P P +P EP
Sbjct: 421 TTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPT-TPKEPAPTTTKKPAPTTP---KEPAP 476
Query: 764 AARAGGSPTAVRSI 777
+PT + +
Sbjct: 477 TTPKETAPTTPKKL 490
Score = 78.2 bits (191), Expect = 3e-14
Identities = 98/399 (24%), Positives = 127/399 (31%), Gaps = 75/399 (18%)
Query: 418 TTTTLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPSTDVPPSPEAGGTTGPWTST 477
T TT+ A E T T TT E + + P+ P P T P +T
Sbjct: 233 TPTTIKSAPT--TPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTT 290
Query: 478 TSEVPRPPEPSQGPSTTSSGGGTGPHPPSGTTLRPPTSSTPGGP------PGAENSTSHQ 531
T P P+ P+T T P P+ TT + PT +TP P P
Sbjct: 291 TKSAPTTPK-EPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA 349
Query: 532 PATPGGDTAQTPK-PGTSQPMPPGVGTSTSHQPATP----------SGGTAQTPEPGTSQ 580
P P TPK P + P P T+ P TP + T + P P T++
Sbjct: 350 PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 409
Query: 581 -----PMPPSMGTSTSHQPATPGGGTAQTP---------EAGTSQPMPPGMGTSTSHQPT 626
P PS T+ P TP TP E + P P T+ PT
Sbjct: 410 SAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPT 469
Query: 627 TPGGGTAQTP-EPGTSQPMPLSKSTPSSGGGPSEDKRFSVVDMAALGGVLGALLLLALLG 685
TP TP E + P L+ +TP + +K
Sbjct: 470 TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKP----------------------- 506
Query: 686 LAVLVHKHYGPRLKCCSGKAPEPQPQGFDNQAFLPDHKANWAPVPSPTHDPKPAEAPMPA 745
A + P EP P P+ A P + + PK P
Sbjct: 507 -APTTPEELAPT------TPEEPTPT-------TPEEPAPTTPKAAAPNTPKEPAPTTPK 552
Query: 746 EPAPPGPASPGGAPEPPAAARAGGSPTAVRSILTKERRP 784
EPAP P P AP P A +P KE P
Sbjct: 553 EPAPTTPKEP--APTTPKET-APTTPKGTAPTTLKEPAP 588
Score = 69.7 bits (169), Expect = 1e-11
Identities = 76/266 (28%), Positives = 96/266 (36%), Gaps = 28/266 (10%)
Query: 417 LTTTTLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPSTDVPPSPEAGGTTGPW-- 474
LT TT + E A T TT E + E P+ P +P+A P
Sbjct: 490 LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPA---PTTPKAAAPNTPKEP 546
Query: 475 TSTTSEVPRPPEPSQ-GPSTTSSGGGTGPHPPSGTTLRPPTSSTPGGP------------ 521
TT + P P P + P+T T P + TTL+ P +TP P
Sbjct: 547 APTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKE 606
Query: 522 PGAENSTSHQPATPGGDTAQTPK-PGTSQPMPPGVGTSTSHQPAT---PSGGTAQTPEPG 577
P + P TP G TPK P + P P T P T P+ T + P P
Sbjct: 607 PTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPK 666
Query: 578 TSQPMP---PSMGTSTSHQPATPGGGTAQTP-EAGTSQPMPPGMGTSTSHQPTTPGGGT- 632
P P+ TS P TP TP E + P P T + PTT T
Sbjct: 667 ELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTP 726
Query: 633 AQTPEPGTSQPMPLSKSTPSSGGGPS 658
T EP T P +STP P+
Sbjct: 727 TTTKEPTTIHKSP-DESTPELSAEPT 751
Score = 68.2 bits (165), Expect = 3e-11
Identities = 83/356 (23%), Positives = 120/356 (33%), Gaps = 47/356 (13%)
Query: 432 VEAHNTVTSGTATTVIEIQVSEQEPPSTDVPPSPEAGGTTGPWTSTTSEVPRPPEPSQGP 491
V TV + TT + ++ + +T + T+ + TS+V P P +
Sbjct: 144 VNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTP-KAE 202
Query: 492 STTSSGGGTGPHPPSGTTLRPPTSSTPGGPPGAENSTSHQPATPGGDTAQTPKPGTSQPM 551
+TT T P P+ TT + P S+TP P + P TP T K + P
Sbjct: 203 TTTKGPALTTPKEPTPTTPKEPASTTPKEP--TPTTIKSAPTTPKEPAPTTTKSAPTTPK 260
Query: 552 PPGVGTSTSHQPATP---SGGTAQTPEPGTSQ-----PMPPSMGTSTSHQPATPGGGTAQ 603
P T+ P TP + T + P P T++ P P+ T P TP
Sbjct: 261 EPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPT 320
Query: 604 TPEAGTSQPMPPGMGTSTSHQPTTPGGGTAQTP-EPGTSQPMPLSKSTPSSGGGPSEDKR 662
TP+ T T+ PTTP P +P + P + +TP P+ K
Sbjct: 321 TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKE-PAPTTTKE 379
Query: 663 FSVVDMAALGGVLGALLLLALLGLAVLVHKHYGP-RLKCCSGKAPEPQPQGFDNQAFLPD 721
S K P K EP P + P
Sbjct: 380 PSPT-----------------------TPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPK 416
Query: 722 HKANWAPVPSPTHDPKPA--EAPMPAEPAPPGPASPGGAPEPPAAARAGGSPTAVR 775
P P+ T +P P + P P P P P +P EP +PT +
Sbjct: 417 E-----PSPTTTKEPAPTTPKEPAPTTPKKPAPTTP---KEPAPTTPKEPAPTTTK 464
Score = 60.5 bits (145), Expect = 6e-09
Identities = 62/229 (27%), Positives = 93/229 (40%), Gaps = 32/229 (13%)
Query: 437 TVTSGTATTVIEIQVSEQEPPSTDVPPSPEAGGTTGPWT--STTSEVPRPPEPSQGPSTT 494
T GTA T ++ P+T P+P T P T P+ P P + TT
Sbjct: 618 TTPKGTAPTT-----PKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 672
Query: 495 SSGGGTGPHPPSGTTLRPPTSSTP--GGPPGAENSTSHQPATPGGDTAQTPKPGTSQPMP 552
+ G P+ TT P +TP P + P P T +TP P TS+
Sbjct: 673 TKG-------PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVST 725
Query: 553 PGVGTSTSHQPATPSGGTAQTPEPGTSQPMPPSMGTSTSHQPATPGGGTAQTPEAGTSQP 612
P +T+ +P T ++ +++P P ++ S P PG T +TP A T
Sbjct: 726 P----TTTKEPTTIHKSPDESTPELSAEPTPKALENS----PKEPGVPTTKTP-AATKPE 776
Query: 613 MPPGMGTSTSHQPTTPGGGTAQTPEPGTSQPMPLSKSTPSSGGGPSEDK 661
M T+T+ TT TPE T+ P ++K T ++ +E K
Sbjct: 777 M-----TTTAKDKTTE-RDLRTTPETTTAAP-KMTKETATTTEKTTESK 818
Score = 41.6 bits (96), Expect = 0.003
Identities = 55/202 (27%), Positives = 74/202 (36%), Gaps = 32/202 (15%)
Query: 430 AEVEAHNTVTSGTATTVIEIQVS---EQEPPSTDVPPSPEAGGTTGPWTSTTSEVPRPPE 486
A E T T G +T + ++ P+T P+P P TT E P P
Sbjct: 664 APKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAP---TTPETPPPTT 720
Query: 487 PSQGPSTTSSGGGTGPHPPSGTTLRPPTSSTPGGPPGAENSTSHQPATPGGDTAQTPKPG 546
TT+ T P +T P S P ENS P PG T +TP
Sbjct: 721 SEVSTPTTTKEPTTIHKSPDEST---PELSAEPTPKALENS----PKEPGVPTTKTP-AA 772
Query: 547 TSQPMPPGVGTSTSHQPATPSGGTAQTPEPGTSQPMPPSMGTSTSHQPATPGGGTAQTPE 606
T M +T+ + T TPE T+ P + T+T+ + T TA T +
Sbjct: 773 TKPEM------TTTAKDKTTERDLRTTPETTTAAP-KMTKETATTTEKTTESKITATTTQ 825
Query: 607 AGTSQPMPPGMGTSTSHQPTTP 628
TST+ Q TTP
Sbjct: 826 V-----------TSTTTQDTTP 836
Score = 32.3 bits (72), Expect = 1.9
Identities = 54/229 (23%), Positives = 77/229 (33%), Gaps = 32/229 (13%)
Query: 581 PMPPSMGTSTS------HQPATPGGGTAQ------TPEAGTSQP------MPPGMGTSTS 622
P PP + + S + TP T Q +P+ T++P +PP TS
Sbjct: 80 PKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKE 139
Query: 623 HQPTTPGGGTAQTPEPGTS--QPMPLSKSTPSSGGGPSEDKRFSVVDMAALGGVLGALLL 680
T T +T E T+ Q K +S ++ S D+A VL
Sbjct: 140 TSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTP 199
Query: 681 LA---LLGLAVLVHKHYGPRL--KCCSGKAPEPQPQGFDNQAFLPDHKANWAPVPSPTHD 735
A G A+ K P + S EP P + P A +PT
Sbjct: 200 KAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTP 259
Query: 736 PKPAEAPMPAEPAPPGPASPGGAPEPPAAARAGGSPTAVRSILTKERRP 784
+PA P P P +P EP +PT +S T + P
Sbjct: 260 KEPA----PTTTKEPAPTTP---KEPAPTTTKEPAPTTTKSAPTTPKEP 301
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 79.7 bits (195), Expect = 1e-14
Identities = 99/360 (27%), Positives = 129/360 (35%), Gaps = 42/360 (11%)
Query: 434 AHNTVTSGTATTVIEIQVSEQEP-PSTDVPPSPEAGGTTGPWTSTTSEVPRPPEPSQ-GP 491
A T T TT E + +EP P+T P+P A P TT + P P P + P
Sbjct: 359 APTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP---TTPKEPAPTTPKEPAP 415
Query: 492 STTSSGGGTGPHPPSGTTLRPP-----------TSSTPGGPPGAENSTSHQPA--TPGGD 538
+TT T P P+ TT + T S P P +T+ +PA TP
Sbjct: 416 TTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP 475
Query: 539 TAQTPK-PGTSQPMPPGVGTSTSHQPATPSGGTAQTPEPGTSQPMPPSMGTSTSHQPATP 597
TPK P + P P T P P+ T + P P T P P+ T P TP
Sbjct: 476 APTTPKKPAPTTPKEPAPTT-----PKEPAPTTTKKPAPTT--PKEPAPTTPKETAPTTP 528
Query: 598 GGGTAQTPE-AGTSQPMPPGMGTSTSHQPTTPGGGTAQTP-EPGTSQPMPLSKSTPSSGG 655
T TPE + P P T PTTP T TP EP + P + +TP
Sbjct: 529 KKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA 588
Query: 656 GPSEDKRFSVVDMAALGGVLGALLLLALLGLAVLVHKHYGPRLKCCSGKAPEPQPQGFDN 715
+ + G A K P + K P P+
Sbjct: 589 PTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAP----TTPKKPAPKELA--- 641
Query: 716 QAFLPDHKANWAPVPSPTHDPKPAEAPMPAEPAPPGPASPGGAPEPPAAARAGGSPTAVR 775
+ + P+PT PK P EPAP P P AP P G +PT ++
Sbjct: 642 PTTTKEPTSTTCDKPAPT-TPKGTAPTTPKEPAPTTPKEP--APTTP----KGTAPTTLK 694
Score = 78.6 bits (192), Expect = 2e-14
Identities = 101/379 (26%), Positives = 134/379 (35%), Gaps = 26/379 (6%)
Query: 420 TTLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPSTDVPPSPEAGGTTGPWTSTTS 479
TT + + A T S TT + + P+T PSP TT TT
Sbjct: 416 TTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPT---TTKEPAPTTP 472
Query: 480 EVPRPPEPSQ-GPSTTSSGGGTGPHPPSGTTLRPPTSSTPGGP-PGAENSTSHQPATPGG 537
+ P P P + P+T T P P+ TT + P +TP P P T+ P TP
Sbjct: 473 KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA--PTTPKK 530
Query: 538 DTAQTP-KPGTSQPMPPGVGTSTSHQPATPSGGTAQTPEPGTSQPMPPSMGTSTSHQPAT 596
T TP K + P P T P TP T TPE +P P + + + P
Sbjct: 531 LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPE----EPAPTTPKAAAPNTPKE 586
Query: 597 PGGGTAQTPEAGTSQPMPPGMGTSTSHQPTTPGGG---TAQTPEPGTSQ---PMPLSKST 650
P T + P T P P T PTTP G T + P P T + P L+ +T
Sbjct: 587 PAPTTPKEPAPTT--PKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 644
Query: 651 PSSGGGPSEDKRFSVVDMAALGGVLGALLLLALLGLAVLVHKHYGPR-LKCCSGKAPE-P 708
+ DK A K P LK + P+ P
Sbjct: 645 TKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKP 704
Query: 709 QPQGFDNQAFLPDHKANWAPVPSPTHDPKPAEAPMPAEPAPPGPASPG-GAPE-PPAAAR 766
P+ + + P+PT PK P EPAP P P PE PP
Sbjct: 705 APKELAPTT-TKGPTSTTSDKPAPT-TPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTS 762
Query: 767 AGGSPTAVRSILTKERRPE 785
+PT + T + P+
Sbjct: 763 EVSTPTTTKEPTTIHKSPD 781
Score = 78.2 bits (191), Expect = 3e-14
Identities = 96/374 (25%), Positives = 129/374 (34%), Gaps = 52/374 (13%)
Query: 418 TTTTLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPSTDV--PPSPEAGGTTGPWT 475
TTTT Q + TS T IE ++ P++ V P+P+A TT
Sbjct: 196 TTTTNKQTST-----DGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPA 250
Query: 476 STTSEVPRPPEPSQGPSTTSSGGGTGPHPPSGTTLRPPTSSTPGGPPGAENSTSHQPATP 535
TT + P P P + STT P P+ TT++ ++ P S P P
Sbjct: 251 LTTPKEPTPTTPKEPASTT-------PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEP 303
Query: 536 GGDTAQTPKPGTSQPMPPGVGTSTSHQPATPSGGTAQTPEPGTSQPMPPSMGTSTSHQPA 595
T + P P T P P T+ P T EP + P P+ T P
Sbjct: 304 APTTTKEPAPTT--PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPT 361
Query: 596 TPGGGTAQTPEAG---TSQPMPPGMGTSTSHQPTTPGGGTAQTPEPGT-SQPMPLSKSTP 651
TP T TP+ T +P P P P T + P P T +P P + P
Sbjct: 362 TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEP 421
Query: 652 SSGGGPSEDKRFSVVDMAALGGVLGALLLLALLGLAVLVHKHYGPRLKCCSGKAP-EPQP 710
S P+ K + + A K P + P EP P
Sbjct: 422 S----PTTPKEPAPTTTKS----------------APTTTKEPAPTTTKSAPTTPKEPSP 461
Query: 711 QGFDNQA-FLPDHKANWAP-VPSPTHDPKPAEAPMPAEPAP-----PGPASPGGAPEPPA 763
A P A P P+PT +PA P EPAP P P +P EP
Sbjct: 462 TTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPT-TPKEPAPTTTKKPAPTTP---KEPAP 517
Query: 764 AARAGGSPTAVRSI 777
+PT + +
Sbjct: 518 TTPKETAPTTPKKL 531
Score = 78.2 bits (191), Expect = 3e-14
Identities = 98/399 (24%), Positives = 127/399 (31%), Gaps = 75/399 (18%)
Query: 418 TTTTLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPSTDVPPSPEAGGTTGPWTST 477
T TT+ A E T T TT E + + P+ P P T P +T
Sbjct: 274 TPTTIKSAPT--TPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTT 331
Query: 478 TSEVPRPPEPSQGPSTTSSGGGTGPHPPSGTTLRPPTSSTPGGP------PGAENSTSHQ 531
T P P+ P+T T P P+ TT + PT +TP P P
Sbjct: 332 TKSAPTTPK-EPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA 390
Query: 532 PATPGGDTAQTPK-PGTSQPMPPGVGTSTSHQPATP----------SGGTAQTPEPGTSQ 580
P P TPK P + P P T+ P TP + T + P P T++
Sbjct: 391 PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 450
Query: 581 -----PMPPSMGTSTSHQPATPGGGTAQTP---------EAGTSQPMPPGMGTSTSHQPT 626
P PS T+ P TP TP E + P P T+ PT
Sbjct: 451 SAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPT 510
Query: 627 TPGGGTAQTP-EPGTSQPMPLSKSTPSSGGGPSEDKRFSVVDMAALGGVLGALLLLALLG 685
TP TP E + P L+ +TP + +K
Sbjct: 511 TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKP----------------------- 547
Query: 686 LAVLVHKHYGPRLKCCSGKAPEPQPQGFDNQAFLPDHKANWAPVPSPTHDPKPAEAPMPA 745
A + P EP P P+ A P + + PK P
Sbjct: 548 -APTTPEELAPT------TPEEPTPT-------TPEEPAPTTPKAAAPNTPKEPAPTTPK 593
Query: 746 EPAPPGPASPGGAPEPPAAARAGGSPTAVRSILTKERRP 784
EPAP P P AP P A +P KE P
Sbjct: 594 EPAPTTPKEP--APTTPKET-APTTPKGTAPTTLKEPAP 629
Score = 69.7 bits (169), Expect = 1e-11
Identities = 76/266 (28%), Positives = 96/266 (36%), Gaps = 28/266 (10%)
Query: 417 LTTTTLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPSTDVPPSPEAGGTTGPW-- 474
LT TT + E A T TT E + E P+ P +P+A P
Sbjct: 531 LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPA---PTTPKAAAPNTPKEP 587
Query: 475 TSTTSEVPRPPEPSQ-GPSTTSSGGGTGPHPPSGTTLRPPTSSTPGGP------------ 521
TT + P P P + P+T T P + TTL+ P +TP P
Sbjct: 588 APTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKE 647
Query: 522 PGAENSTSHQPATPGGDTAQTPK-PGTSQPMPPGVGTSTSHQPAT---PSGGTAQTPEPG 577
P + P TP G TPK P + P P T P T P+ T + P P
Sbjct: 648 PTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPK 707
Query: 578 TSQPMP---PSMGTSTSHQPATPGGGTAQTP-EAGTSQPMPPGMGTSTSHQPTTPGGGT- 632
P P+ TS P TP TP E + P P T + PTT T
Sbjct: 708 ELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTP 767
Query: 633 AQTPEPGTSQPMPLSKSTPSSGGGPS 658
T EP T P +STP P+
Sbjct: 768 TTTKEPTTIHKSP-DESTPELSAEPT 792
Score = 68.2 bits (165), Expect = 3e-11
Identities = 83/356 (23%), Positives = 120/356 (33%), Gaps = 47/356 (13%)
Query: 432 VEAHNTVTSGTATTVIEIQVSEQEPPSTDVPPSPEAGGTTGPWTSTTSEVPRPPEPSQGP 491
V TV + TT + ++ + +T + T+ + TS+V P P +
Sbjct: 185 VNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTP-KAE 243
Query: 492 STTSSGGGTGPHPPSGTTLRPPTSSTPGGPPGAENSTSHQPATPGGDTAQTPKPGTSQPM 551
+TT T P P+ TT + P S+TP P + P TP T K + P
Sbjct: 244 TTTKGPALTTPKEPTPTTPKEPASTTPKEP--TPTTIKSAPTTPKEPAPTTTKSAPTTPK 301
Query: 552 PPGVGTSTSHQPATP---SGGTAQTPEPGTSQ-----PMPPSMGTSTSHQPATPGGGTAQ 603
P T+ P TP + T + P P T++ P P+ T P TP
Sbjct: 302 EPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPT 361
Query: 604 TPEAGTSQPMPPGMGTSTSHQPTTPGGGTAQTP-EPGTSQPMPLSKSTPSSGGGPSEDKR 662
TP+ T T+ PTTP P +P + P + +TP P+ K
Sbjct: 362 TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKE-PAPTTTKE 420
Query: 663 FSVVDMAALGGVLGALLLLALLGLAVLVHKHYGP-RLKCCSGKAPEPQPQGFDNQAFLPD 721
S K P K EP P + P
Sbjct: 421 PSPT-----------------------TPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPK 457
Query: 722 HKANWAPVPSPTHDPKPA--EAPMPAEPAPPGPASPGGAPEPPAAARAGGSPTAVR 775
P P+ T +P P + P P P P P +P EP +PT +
Sbjct: 458 E-----PSPTTTKEPAPTTPKEPAPTTPKKPAPTTP---KEPAPTTPKEPAPTTTK 505
Score = 60.5 bits (145), Expect = 6e-09
Identities = 62/229 (27%), Positives = 93/229 (40%), Gaps = 32/229 (13%)
Query: 437 TVTSGTATTVIEIQVSEQEPPSTDVPPSPEAGGTTGPWT--STTSEVPRPPEPSQGPSTT 494
T GTA T ++ P+T P+P T P T P+ P P + TT
Sbjct: 659 TTPKGTAPTT-----PKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 713
Query: 495 SSGGGTGPHPPSGTTLRPPTSSTP--GGPPGAENSTSHQPATPGGDTAQTPKPGTSQPMP 552
+ G P+ TT P +TP P + P P T +TP P TS+
Sbjct: 714 TKG-------PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVST 766
Query: 553 PGVGTSTSHQPATPSGGTAQTPEPGTSQPMPPSMGTSTSHQPATPGGGTAQTPEAGTSQP 612
P +T+ +P T ++ +++P P ++ S P PG T +TP A T
Sbjct: 767 P----TTTKEPTTIHKSPDESTPELSAEPTPKALENS----PKEPGVPTTKTP-AATKPE 817
Query: 613 MPPGMGTSTSHQPTTPGGGTAQTPEPGTSQPMPLSKSTPSSGGGPSEDK 661
M T+T+ TT TPE T+ P ++K T ++ +E K
Sbjct: 818 M-----TTTAKDKTTE-RDLRTTPETTTAAP-KMTKETATTTEKTTESK 859
Score = 41.6 bits (96), Expect = 0.003
Identities = 55/202 (27%), Positives = 74/202 (36%), Gaps = 32/202 (15%)
Query: 430 AEVEAHNTVTSGTATTVIEIQVS---EQEPPSTDVPPSPEAGGTTGPWTSTTSEVPRPPE 486
A E T T G +T + ++ P+T P+P P TT E P P
Sbjct: 705 APKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAP---TTPETPPPTT 761
Query: 487 PSQGPSTTSSGGGTGPHPPSGTTLRPPTSSTPGGPPGAENSTSHQPATPGGDTAQTPKPG 546
TT+ T P +T P S P ENS P PG T +TP
Sbjct: 762 SEVSTPTTTKEPTTIHKSPDEST---PELSAEPTPKALENS----PKEPGVPTTKTP-AA 813
Query: 547 TSQPMPPGVGTSTSHQPATPSGGTAQTPEPGTSQPMPPSMGTSTSHQPATPGGGTAQTPE 606
T M +T+ + T TPE T+ P + T+T+ + T TA T +
Sbjct: 814 TKPEM------TTTAKDKTTERDLRTTPETTTAAP-KMTKETATTTEKTTESKITATTTQ 866
Query: 607 AGTSQPMPPGMGTSTSHQPTTP 628
TST+ Q TTP
Sbjct: 867 V-----------TSTTTQDTTP 877
Score = 32.3 bits (72), Expect = 1.9
Identities = 54/229 (23%), Positives = 77/229 (33%), Gaps = 32/229 (13%)
Query: 581 PMPPSMGTSTS------HQPATPGGGTAQ------TPEAGTSQP------MPPGMGTSTS 622
P PP + + S + TP T Q +P+ T++P +PP TS
Sbjct: 121 PKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKE 180
Query: 623 HQPTTPGGGTAQTPEPGTS--QPMPLSKSTPSSGGGPSEDKRFSVVDMAALGGVLGALLL 680
T T +T E T+ Q K +S ++ S D+A VL
Sbjct: 181 TSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTP 240
Query: 681 LA---LLGLAVLVHKHYGPRL--KCCSGKAPEPQPQGFDNQAFLPDHKANWAPVPSPTHD 735
A G A+ K P + S EP P + P A +PT
Sbjct: 241 KAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTP 300
Query: 736 PKPAEAPMPAEPAPPGPASPGGAPEPPAAARAGGSPTAVRSILTKERRP 784
+PA P P P +P EP +PT +S T + P
Sbjct: 301 KEPA----PTTTKEPAPTTP---KEPAPTTTKEPAPTTTKSAPTTPKEP 342
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 79.7 bits (195), Expect = 1e-14
Identities = 99/360 (27%), Positives = 129/360 (35%), Gaps = 42/360 (11%)
Query: 434 AHNTVTSGTATTVIEIQVSEQEP-PSTDVPPSPEAGGTTGPWTSTTSEVPRPPEPSQ-GP 491
A T T TT E + +EP P+T P+P A P TT + P P P + P
Sbjct: 411 APTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP---TTPKEPAPTTPKEPAP 467
Query: 492 STTSSGGGTGPHPPSGTTLRPP-----------TSSTPGGPPGAENSTSHQPA--TPGGD 538
+TT T P P+ TT + T S P P +T+ +PA TP
Sbjct: 468 TTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP 527
Query: 539 TAQTPK-PGTSQPMPPGVGTSTSHQPATPSGGTAQTPEPGTSQPMPPSMGTSTSHQPATP 597
TPK P + P P T P P+ T + P P T P P+ T P TP
Sbjct: 528 APTTPKKPAPTTPKEPAPTT-----PKEPAPTTTKKPAPTT--PKEPAPTTPKETAPTTP 580
Query: 598 GGGTAQTPE-AGTSQPMPPGMGTSTSHQPTTPGGGTAQTP-EPGTSQPMPLSKSTPSSGG 655
T TPE + P P T PTTP T TP EP + P + +TP
Sbjct: 581 KKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA 640
Query: 656 GPSEDKRFSVVDMAALGGVLGALLLLALLGLAVLVHKHYGPRLKCCSGKAPEPQPQGFDN 715
+ + G A K P + K P P+
Sbjct: 641 PTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAP----TTPKKPAPKELA--- 693
Query: 716 QAFLPDHKANWAPVPSPTHDPKPAEAPMPAEPAPPGPASPGGAPEPPAAARAGGSPTAVR 775
+ + P+PT PK P EPAP P P AP P G +PT ++
Sbjct: 694 PTTTKEPTSTTCDKPAPT-TPKGTAPTTPKEPAPTTPKEP--APTTP----KGTAPTTLK 746
Score = 78.6 bits (192), Expect = 2e-14
Identities = 101/379 (26%), Positives = 134/379 (35%), Gaps = 26/379 (6%)
Query: 420 TTLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPSTDVPPSPEAGGTTGPWTSTTS 479
TT + + A T S TT + + P+T PSP TT TT
Sbjct: 468 TTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPT---TTKEPAPTTP 524
Query: 480 EVPRPPEPSQ-GPSTTSSGGGTGPHPPSGTTLRPPTSSTPGGP-PGAENSTSHQPATPGG 537
+ P P P + P+T T P P+ TT + P +TP P P T+ P TP
Sbjct: 525 KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA--PTTPKK 582
Query: 538 DTAQTP-KPGTSQPMPPGVGTSTSHQPATPSGGTAQTPEPGTSQPMPPSMGTSTSHQPAT 596
T TP K + P P T P TP T TPE +P P + + + P
Sbjct: 583 LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPE----EPAPTTPKAAAPNTPKE 638
Query: 597 PGGGTAQTPEAGTSQPMPPGMGTSTSHQPTTPGGG---TAQTPEPGTSQ---PMPLSKST 650
P T + P T P P T PTTP G T + P P T + P L+ +T
Sbjct: 639 PAPTTPKEPAPTT--PKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 696
Query: 651 PSSGGGPSEDKRFSVVDMAALGGVLGALLLLALLGLAVLVHKHYGPR-LKCCSGKAPE-P 708
+ DK A K P LK + P+ P
Sbjct: 697 TKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKP 756
Query: 709 QPQGFDNQAFLPDHKANWAPVPSPTHDPKPAEAPMPAEPAPPGPASPG-GAPE-PPAAAR 766
P+ + + P+PT PK P EPAP P P PE PP
Sbjct: 757 APKELAPTT-TKGPTSTTSDKPAPT-TPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTS 814
Query: 767 AGGSPTAVRSILTKERRPE 785
+PT + T + P+
Sbjct: 815 EVSTPTTTKEPTTIHKSPD 833
Score = 78.2 bits (191), Expect = 3e-14
Identities = 96/374 (25%), Positives = 129/374 (34%), Gaps = 52/374 (13%)
Query: 418 TTTTLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPSTDV--PPSPEAGGTTGPWT 475
TTTT Q + TS T IE ++ P++ V P+P+A TT
Sbjct: 248 TTTTNKQTST-----DGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPA 302
Query: 476 STTSEVPRPPEPSQGPSTTSSGGGTGPHPPSGTTLRPPTSSTPGGPPGAENSTSHQPATP 535
TT + P P P + STT P P+ TT++ ++ P S P P
Sbjct: 303 LTTPKEPTPTTPKEPASTT-------PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEP 355
Query: 536 GGDTAQTPKPGTSQPMPPGVGTSTSHQPATPSGGTAQTPEPGTSQPMPPSMGTSTSHQPA 595
T + P P T P P T+ P T EP + P P+ T P
Sbjct: 356 APTTTKEPAPTT--PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPT 413
Query: 596 TPGGGTAQTPEAG---TSQPMPPGMGTSTSHQPTTPGGGTAQTPEPGT-SQPMPLSKSTP 651
TP T TP+ T +P P P P T + P P T +P P + P
Sbjct: 414 TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEP 473
Query: 652 SSGGGPSEDKRFSVVDMAALGGVLGALLLLALLGLAVLVHKHYGPRLKCCSGKAP-EPQP 710
S P+ K + + A K P + P EP P
Sbjct: 474 S----PTTPKEPAPTTTKS----------------APTTTKEPAPTTTKSAPTTPKEPSP 513
Query: 711 QGFDNQA-FLPDHKANWAP-VPSPTHDPKPAEAPMPAEPAP-----PGPASPGGAPEPPA 763
A P A P P+PT +PA P EPAP P P +P EP
Sbjct: 514 TTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPT-TPKEPAPTTTKKPAPTTP---KEPAP 569
Query: 764 AARAGGSPTAVRSI 777
+PT + +
Sbjct: 570 TTPKETAPTTPKKL 583
Score = 78.2 bits (191), Expect = 3e-14
Identities = 98/399 (24%), Positives = 127/399 (31%), Gaps = 75/399 (18%)
Query: 418 TTTTLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPSTDVPPSPEAGGTTGPWTST 477
T TT+ A E T T TT E + + P+ P P T P +T
Sbjct: 326 TPTTIKSAPT--TPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTT 383
Query: 478 TSEVPRPPEPSQGPSTTSSGGGTGPHPPSGTTLRPPTSSTPGGP------PGAENSTSHQ 531
T P P+ P+T T P P+ TT + PT +TP P P
Sbjct: 384 TKSAPTTPK-EPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA 442
Query: 532 PATPGGDTAQTPK-PGTSQPMPPGVGTSTSHQPATP----------SGGTAQTPEPGTSQ 580
P P TPK P + P P T+ P TP + T + P P T++
Sbjct: 443 PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 502
Query: 581 -----PMPPSMGTSTSHQPATPGGGTAQTP---------EAGTSQPMPPGMGTSTSHQPT 626
P PS T+ P TP TP E + P P T+ PT
Sbjct: 503 SAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPT 562
Query: 627 TPGGGTAQTP-EPGTSQPMPLSKSTPSSGGGPSEDKRFSVVDMAALGGVLGALLLLALLG 685
TP TP E + P L+ +TP + +K
Sbjct: 563 TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKP----------------------- 599
Query: 686 LAVLVHKHYGPRLKCCSGKAPEPQPQGFDNQAFLPDHKANWAPVPSPTHDPKPAEAPMPA 745
A + P EP P P+ A P + + PK P
Sbjct: 600 -APTTPEELAPT------TPEEPTPT-------TPEEPAPTTPKAAAPNTPKEPAPTTPK 645
Query: 746 EPAPPGPASPGGAPEPPAAARAGGSPTAVRSILTKERRP 784
EPAP P P AP P A +P KE P
Sbjct: 646 EPAPTTPKEP--APTTPKET-APTTPKGTAPTTLKEPAP 681
Score = 69.7 bits (169), Expect = 1e-11
Identities = 76/266 (28%), Positives = 96/266 (36%), Gaps = 28/266 (10%)
Query: 417 LTTTTLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPSTDVPPSPEAGGTTGPW-- 474
LT TT + E A T TT E + E P+ P +P+A P
Sbjct: 583 LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPA---PTTPKAAAPNTPKEP 639
Query: 475 TSTTSEVPRPPEPSQ-GPSTTSSGGGTGPHPPSGTTLRPPTSSTPGGP------------ 521
TT + P P P + P+T T P + TTL+ P +TP P
Sbjct: 640 APTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKE 699
Query: 522 PGAENSTSHQPATPGGDTAQTPK-PGTSQPMPPGVGTSTSHQPAT---PSGGTAQTPEPG 577
P + P TP G TPK P + P P T P T P+ T + P P
Sbjct: 700 PTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPK 759
Query: 578 TSQPMP---PSMGTSTSHQPATPGGGTAQTP-EAGTSQPMPPGMGTSTSHQPTTPGGGT- 632
P P+ TS P TP TP E + P P T + PTT T
Sbjct: 760 ELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTP 819
Query: 633 AQTPEPGTSQPMPLSKSTPSSGGGPS 658
T EP T P +STP P+
Sbjct: 820 TTTKEPTTIHKSP-DESTPELSAEPT 844
Score = 68.2 bits (165), Expect = 3e-11
Identities = 83/356 (23%), Positives = 120/356 (33%), Gaps = 47/356 (13%)
Query: 432 VEAHNTVTSGTATTVIEIQVSEQEPPSTDVPPSPEAGGTTGPWTSTTSEVPRPPEPSQGP 491
V TV + TT + ++ + +T + T+ + TS+V P P +
Sbjct: 237 VNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTP-KAE 295
Query: 492 STTSSGGGTGPHPPSGTTLRPPTSSTPGGPPGAENSTSHQPATPGGDTAQTPKPGTSQPM 551
+TT T P P+ TT + P S+TP P + P TP T K + P
Sbjct: 296 TTTKGPALTTPKEPTPTTPKEPASTTPKEP--TPTTIKSAPTTPKEPAPTTTKSAPTTPK 353
Query: 552 PPGVGTSTSHQPATP---SGGTAQTPEPGTSQ-----PMPPSMGTSTSHQPATPGGGTAQ 603
P T+ P TP + T + P P T++ P P+ T P TP
Sbjct: 354 EPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPT 413
Query: 604 TPEAGTSQPMPPGMGTSTSHQPTTPGGGTAQTP-EPGTSQPMPLSKSTPSSGGGPSEDKR 662
TP+ T T+ PTTP P +P + P + +TP P+ K
Sbjct: 414 TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKE-PAPTTTKE 472
Query: 663 FSVVDMAALGGVLGALLLLALLGLAVLVHKHYGP-RLKCCSGKAPEPQPQGFDNQAFLPD 721
S K P K EP P + P
Sbjct: 473 PSPT-----------------------TPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPK 509
Query: 722 HKANWAPVPSPTHDPKPA--EAPMPAEPAPPGPASPGGAPEPPAAARAGGSPTAVR 775
P P+ T +P P + P P P P P +P EP +PT +
Sbjct: 510 E-----PSPTTTKEPAPTTPKEPAPTTPKKPAPTTP---KEPAPTTPKEPAPTTTK 557
Score = 60.5 bits (145), Expect = 6e-09
Identities = 62/229 (27%), Positives = 93/229 (40%), Gaps = 32/229 (13%)
Query: 437 TVTSGTATTVIEIQVSEQEPPSTDVPPSPEAGGTTGPWT--STTSEVPRPPEPSQGPSTT 494
T GTA T ++ P+T P+P T P T P+ P P + TT
Sbjct: 711 TTPKGTAPTT-----PKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 765
Query: 495 SSGGGTGPHPPSGTTLRPPTSSTP--GGPPGAENSTSHQPATPGGDTAQTPKPGTSQPMP 552
+ G P+ TT P +TP P + P P T +TP P TS+
Sbjct: 766 TKG-------PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVST 818
Query: 553 PGVGTSTSHQPATPSGGTAQTPEPGTSQPMPPSMGTSTSHQPATPGGGTAQTPEAGTSQP 612
P +T+ +P T ++ +++P P ++ S P PG T +TP A T
Sbjct: 819 P----TTTKEPTTIHKSPDESTPELSAEPTPKALENS----PKEPGVPTTKTP-AATKPE 869
Query: 613 MPPGMGTSTSHQPTTPGGGTAQTPEPGTSQPMPLSKSTPSSGGGPSEDK 661
M T+T+ TT TPE T+ P ++K T ++ +E K
Sbjct: 870 M-----TTTAKDKTTE-RDLRTTPETTTAAP-KMTKETATTTEKTTESK 911
Score = 43.5 bits (101), Expect = 8e-04
Identities = 79/345 (22%), Positives = 110/345 (31%), Gaps = 38/345 (11%)
Query: 456 PPSTDVPPSPEAGGTTGPWTSTTSEVPRPPEPSQGPSTTSSGGGTGPHP------PSGTT 509
PPS+ P P T STT P+PP + S T H S ++
Sbjct: 72 PPSSKKAPPPSGASQT--IKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSS 129
Query: 510 LRPPTSSTPGGPPGAENSTSHQPATPGGDTAQTPKPGTSQ---PMPPGVGTSTSHQPATP 566
+SST ++NS +++ K T + P PP V + S
Sbjct: 130 SSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGL---- 185
Query: 567 SGGTAQTPEPGTSQPMPPSMGTSTSHQPATPGGGTAQTPEAGTSQPMPPGMGTSTSHQPT 626
G + P TS + TS A P +PP TS T
Sbjct: 186 DNGDFKVTTPDTSTTQHNKVSTSPKITTAKP---------INPRPSLPPNSDTSKETSLT 236
Query: 627 TPGGGTAQTPEPGTS--QPMPLSKSTPSSGGGPSEDKRFSVVDMAALGGVLGALLLLA-- 682
T +T E T+ Q K +S ++ S D+A VL A
Sbjct: 237 VNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAET 296
Query: 683 -LLGLAVLVHKHYGPRL--KCCSGKAPEPQPQGFDNQAFLPDHKANWAPVPSPTHDPKPA 739
G A+ K P + S EP P + P A +PT +PA
Sbjct: 297 TTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPA 356
Query: 740 EAPMPAEPAPPGPASPGGAPEPPAAARAGGSPTAVRSILTKERRP 784
P P P +P EP +PT +S T + P
Sbjct: 357 ----PTTTKEPAPTTP---KEPAPTTTKEPAPTTTKSAPTTPKEP 394
Score = 41.6 bits (96), Expect = 0.003
Identities = 55/202 (27%), Positives = 74/202 (36%), Gaps = 32/202 (15%)
Query: 430 AEVEAHNTVTSGTATTVIEIQVS---EQEPPSTDVPPSPEAGGTTGPWTSTTSEVPRPPE 486
A E T T G +T + ++ P+T P+P P TT E P P
Sbjct: 757 APKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAP---TTPETPPPTT 813
Query: 487 PSQGPSTTSSGGGTGPHPPSGTTLRPPTSSTPGGPPGAENSTSHQPATPGGDTAQTPKPG 546
TT+ T P +T P S P ENS P PG T +TP
Sbjct: 814 SEVSTPTTTKEPTTIHKSPDEST---PELSAEPTPKALENS----PKEPGVPTTKTP-AA 865
Query: 547 TSQPMPPGVGTSTSHQPATPSGGTAQTPEPGTSQPMPPSMGTSTSHQPATPGGGTAQTPE 606
T M +T+ + T TPE T+ P + T+T+ + T TA T +
Sbjct: 866 TKPEM------TTTAKDKTTERDLRTTPETTTAAP-KMTKETATTTEKTTESKITATTTQ 918
Query: 607 AGTSQPMPPGMGTSTSHQPTTP 628
TST+ Q TTP
Sbjct: 919 V-----------TSTTTQDTTP 929
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 79.7 bits (195), Expect = 1e-14
Identities = 99/360 (27%), Positives = 129/360 (35%), Gaps = 42/360 (11%)
Query: 434 AHNTVTSGTATTVIEIQVSEQEP-PSTDVPPSPEAGGTTGPWTSTTSEVPRPPEPSQ-GP 491
A T T TT E + +EP P+T P+P A P TT + P P P + P
Sbjct: 452 APTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP---TTPKEPAPTTPKEPAP 508
Query: 492 STTSSGGGTGPHPPSGTTLRPP-----------TSSTPGGPPGAENSTSHQPA--TPGGD 538
+TT T P P+ TT + T S P P +T+ +PA TP
Sbjct: 509 TTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP 568
Query: 539 TAQTPK-PGTSQPMPPGVGTSTSHQPATPSGGTAQTPEPGTSQPMPPSMGTSTSHQPATP 597
TPK P + P P T P P+ T + P P T P P+ T P TP
Sbjct: 569 APTTPKKPAPTTPKEPAPTT-----PKEPAPTTTKKPAPTT--PKEPAPTTPKETAPTTP 621
Query: 598 GGGTAQTPE-AGTSQPMPPGMGTSTSHQPTTPGGGTAQTP-EPGTSQPMPLSKSTPSSGG 655
T TPE + P P T PTTP T TP EP + P + +TP
Sbjct: 622 KKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA 681
Query: 656 GPSEDKRFSVVDMAALGGVLGALLLLALLGLAVLVHKHYGPRLKCCSGKAPEPQPQGFDN 715
+ + G A K P + K P P+
Sbjct: 682 PTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAP----TTPKKPAPKELA--- 734
Query: 716 QAFLPDHKANWAPVPSPTHDPKPAEAPMPAEPAPPGPASPGGAPEPPAAARAGGSPTAVR 775
+ + P+PT PK P EPAP P P AP P G +PT ++
Sbjct: 735 PTTTKEPTSTTCDKPAPT-TPKGTAPTTPKEPAPTTPKEP--APTTP----KGTAPTTLK 787
Score = 78.6 bits (192), Expect = 2e-14
Identities = 101/379 (26%), Positives = 134/379 (35%), Gaps = 26/379 (6%)
Query: 420 TTLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPSTDVPPSPEAGGTTGPWTSTTS 479
TT + + A T S TT + + P+T PSP TT TT
Sbjct: 509 TTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPT---TTKEPAPTTP 565
Query: 480 EVPRPPEPSQ-GPSTTSSGGGTGPHPPSGTTLRPPTSSTPGGP-PGAENSTSHQPATPGG 537
+ P P P + P+T T P P+ TT + P +TP P P T+ P TP
Sbjct: 566 KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA--PTTPKK 623
Query: 538 DTAQTP-KPGTSQPMPPGVGTSTSHQPATPSGGTAQTPEPGTSQPMPPSMGTSTSHQPAT 596
T TP K + P P T P TP T TPE +P P + + + P
Sbjct: 624 LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPE----EPAPTTPKAAAPNTPKE 679
Query: 597 PGGGTAQTPEAGTSQPMPPGMGTSTSHQPTTPGGG---TAQTPEPGTSQ---PMPLSKST 650
P T + P T P P T PTTP G T + P P T + P L+ +T
Sbjct: 680 PAPTTPKEPAPTT--PKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 737
Query: 651 PSSGGGPSEDKRFSVVDMAALGGVLGALLLLALLGLAVLVHKHYGPR-LKCCSGKAPE-P 708
+ DK A K P LK + P+ P
Sbjct: 738 TKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKP 797
Query: 709 QPQGFDNQAFLPDHKANWAPVPSPTHDPKPAEAPMPAEPAPPGPASPG-GAPE-PPAAAR 766
P+ + + P+PT PK P EPAP P P PE PP
Sbjct: 798 APKELAPTT-TKGPTSTTSDKPAPT-TPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTS 855
Query: 767 AGGSPTAVRSILTKERRPE 785
+PT + T + P+
Sbjct: 856 EVSTPTTTKEPTTIHKSPD 874
Score = 78.2 bits (191), Expect = 3e-14
Identities = 96/374 (25%), Positives = 129/374 (34%), Gaps = 52/374 (13%)
Query: 418 TTTTLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPSTDV--PPSPEAGGTTGPWT 475
TTTT Q + TS T IE ++ P++ V P+P+A TT
Sbjct: 289 TTTTNKQTST-----DGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPA 343
Query: 476 STTSEVPRPPEPSQGPSTTSSGGGTGPHPPSGTTLRPPTSSTPGGPPGAENSTSHQPATP 535
TT + P P P + STT P P+ TT++ ++ P S P P
Sbjct: 344 LTTPKEPTPTTPKEPASTT-------PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEP 396
Query: 536 GGDTAQTPKPGTSQPMPPGVGTSTSHQPATPSGGTAQTPEPGTSQPMPPSMGTSTSHQPA 595
T + P P T P P T+ P T EP + P P+ T P
Sbjct: 397 APTTTKEPAPTT--PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPT 454
Query: 596 TPGGGTAQTPEAG---TSQPMPPGMGTSTSHQPTTPGGGTAQTPEPGT-SQPMPLSKSTP 651
TP T TP+ T +P P P P T + P P T +P P + P
Sbjct: 455 TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEP 514
Query: 652 SSGGGPSEDKRFSVVDMAALGGVLGALLLLALLGLAVLVHKHYGPRLKCCSGKAP-EPQP 710
S P+ K + + A K P + P EP P
Sbjct: 515 S----PTTPKEPAPTTTKS----------------APTTTKEPAPTTTKSAPTTPKEPSP 554
Query: 711 QGFDNQA-FLPDHKANWAP-VPSPTHDPKPAEAPMPAEPAP-----PGPASPGGAPEPPA 763
A P A P P+PT +PA P EPAP P P +P EP
Sbjct: 555 TTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPT-TPKEPAPTTTKKPAPTTP---KEPAP 610
Query: 764 AARAGGSPTAVRSI 777
+PT + +
Sbjct: 611 TTPKETAPTTPKKL 624
Score = 78.2 bits (191), Expect = 3e-14
Identities = 98/399 (24%), Positives = 127/399 (31%), Gaps = 75/399 (18%)
Query: 418 TTTTLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPSTDVPPSPEAGGTTGPWTST 477
T TT+ A E T T TT E + + P+ P P T P +T
Sbjct: 367 TPTTIKSAPT--TPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTT 424
Query: 478 TSEVPRPPEPSQGPSTTSSGGGTGPHPPSGTTLRPPTSSTPGGP------PGAENSTSHQ 531
T P P+ P+T T P P+ TT + PT +TP P P
Sbjct: 425 TKSAPTTPK-EPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA 483
Query: 532 PATPGGDTAQTPK-PGTSQPMPPGVGTSTSHQPATP----------SGGTAQTPEPGTSQ 580
P P TPK P + P P T+ P TP + T + P P T++
Sbjct: 484 PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 543
Query: 581 -----PMPPSMGTSTSHQPATPGGGTAQTP---------EAGTSQPMPPGMGTSTSHQPT 626
P PS T+ P TP TP E + P P T+ PT
Sbjct: 544 SAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPT 603
Query: 627 TPGGGTAQTP-EPGTSQPMPLSKSTPSSGGGPSEDKRFSVVDMAALGGVLGALLLLALLG 685
TP TP E + P L+ +TP + +K
Sbjct: 604 TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKP----------------------- 640
Query: 686 LAVLVHKHYGPRLKCCSGKAPEPQPQGFDNQAFLPDHKANWAPVPSPTHDPKPAEAPMPA 745
A + P EP P P+ A P + + PK P
Sbjct: 641 -APTTPEELAPT------TPEEPTPT-------TPEEPAPTTPKAAAPNTPKEPAPTTPK 686
Query: 746 EPAPPGPASPGGAPEPPAAARAGGSPTAVRSILTKERRP 784
EPAP P P AP P A +P KE P
Sbjct: 687 EPAPTTPKEP--APTTPKET-APTTPKGTAPTTLKEPAP 722
Score = 69.7 bits (169), Expect = 1e-11
Identities = 76/266 (28%), Positives = 96/266 (36%), Gaps = 28/266 (10%)
Query: 417 LTTTTLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPSTDVPPSPEAGGTTGPW-- 474
LT TT + E A T TT E + E P+ P +P+A P
Sbjct: 624 LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPA---PTTPKAAAPNTPKEP 680
Query: 475 TSTTSEVPRPPEPSQ-GPSTTSSGGGTGPHPPSGTTLRPPTSSTPGGP------------ 521
TT + P P P + P+T T P + TTL+ P +TP P
Sbjct: 681 APTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKE 740
Query: 522 PGAENSTSHQPATPGGDTAQTPK-PGTSQPMPPGVGTSTSHQPAT---PSGGTAQTPEPG 577
P + P TP G TPK P + P P T P T P+ T + P P
Sbjct: 741 PTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPK 800
Query: 578 TSQPMP---PSMGTSTSHQPATPGGGTAQTP-EAGTSQPMPPGMGTSTSHQPTTPGGGT- 632
P P+ TS P TP TP E + P P T + PTT T
Sbjct: 801 ELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTP 860
Query: 633 AQTPEPGTSQPMPLSKSTPSSGGGPS 658
T EP T P +STP P+
Sbjct: 861 TTTKEPTTIHKSP-DESTPELSAEPT 885
Score = 68.2 bits (165), Expect = 3e-11
Identities = 83/356 (23%), Positives = 120/356 (33%), Gaps = 47/356 (13%)
Query: 432 VEAHNTVTSGTATTVIEIQVSEQEPPSTDVPPSPEAGGTTGPWTSTTSEVPRPPEPSQGP 491
V TV + TT + ++ + +T + T+ + TS+V P P +
Sbjct: 278 VNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTP-KAE 336
Query: 492 STTSSGGGTGPHPPSGTTLRPPTSSTPGGPPGAENSTSHQPATPGGDTAQTPKPGTSQPM 551
+TT T P P+ TT + P S+TP P + P TP T K + P
Sbjct: 337 TTTKGPALTTPKEPTPTTPKEPASTTPKEP--TPTTIKSAPTTPKEPAPTTTKSAPTTPK 394
Query: 552 PPGVGTSTSHQPATP---SGGTAQTPEPGTSQ-----PMPPSMGTSTSHQPATPGGGTAQ 603
P T+ P TP + T + P P T++ P P+ T P TP
Sbjct: 395 EPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPT 454
Query: 604 TPEAGTSQPMPPGMGTSTSHQPTTPGGGTAQTP-EPGTSQPMPLSKSTPSSGGGPSEDKR 662
TP+ T T+ PTTP P +P + P + +TP P+ K
Sbjct: 455 TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKE-PAPTTTKE 513
Query: 663 FSVVDMAALGGVLGALLLLALLGLAVLVHKHYGP-RLKCCSGKAPEPQPQGFDNQAFLPD 721
S K P K EP P + P
Sbjct: 514 PSPT-----------------------TPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPK 550
Query: 722 HKANWAPVPSPTHDPKPA--EAPMPAEPAPPGPASPGGAPEPPAAARAGGSPTAVR 775
P P+ T +P P + P P P P P +P EP +PT +
Sbjct: 551 E-----PSPTTTKEPAPTTPKEPAPTTPKKPAPTTP---KEPAPTTPKEPAPTTTK 598
Score = 60.5 bits (145), Expect = 6e-09
Identities = 62/229 (27%), Positives = 93/229 (40%), Gaps = 32/229 (13%)
Query: 437 TVTSGTATTVIEIQVSEQEPPSTDVPPSPEAGGTTGPWT--STTSEVPRPPEPSQGPSTT 494
T GTA T ++ P+T P+P T P T P+ P P + TT
Sbjct: 752 TTPKGTAPTT-----PKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 806
Query: 495 SSGGGTGPHPPSGTTLRPPTSSTP--GGPPGAENSTSHQPATPGGDTAQTPKPGTSQPMP 552
+ G P+ TT P +TP P + P P T +TP P TS+
Sbjct: 807 TKG-------PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVST 859
Query: 553 PGVGTSTSHQPATPSGGTAQTPEPGTSQPMPPSMGTSTSHQPATPGGGTAQTPEAGTSQP 612
P +T+ +P T ++ +++P P ++ S P PG T +TP A T
Sbjct: 860 P----TTTKEPTTIHKSPDESTPELSAEPTPKALENS----PKEPGVPTTKTP-AATKPE 910
Query: 613 MPPGMGTSTSHQPTTPGGGTAQTPEPGTSQPMPLSKSTPSSGGGPSEDK 661
M T+T+ TT TPE T+ P ++K T ++ +E K
Sbjct: 911 M-----TTTAKDKTTE-RDLRTTPETTTAAP-KMTKETATTTEKTTESK 952
Score = 43.5 bits (101), Expect = 8e-04
Identities = 79/345 (22%), Positives = 110/345 (31%), Gaps = 38/345 (11%)
Query: 456 PPSTDVPPSPEAGGTTGPWTSTTSEVPRPPEPSQGPSTTSSGGGTGPHP------PSGTT 509
PPS+ P P T STT P+PP + S T H S ++
Sbjct: 113 PPSSKKAPPPSGASQT--IKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSS 170
Query: 510 LRPPTSSTPGGPPGAENSTSHQPATPGGDTAQTPKPGTSQ---PMPPGVGTSTSHQPATP 566
+SST ++NS +++ K T + P PP V + S
Sbjct: 171 SSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGL---- 226
Query: 567 SGGTAQTPEPGTSQPMPPSMGTSTSHQPATPGGGTAQTPEAGTSQPMPPGMGTSTSHQPT 626
G + P TS + TS A P +PP TS T
Sbjct: 227 DNGDFKVTTPDTSTTQHNKVSTSPKITTAKP---------INPRPSLPPNSDTSKETSLT 277
Query: 627 TPGGGTAQTPEPGTS--QPMPLSKSTPSSGGGPSEDKRFSVVDMAALGGVLGALLLLA-- 682
T +T E T+ Q K +S ++ S D+A VL A
Sbjct: 278 VNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAET 337
Query: 683 -LLGLAVLVHKHYGPRL--KCCSGKAPEPQPQGFDNQAFLPDHKANWAPVPSPTHDPKPA 739
G A+ K P + S EP P + P A +PT +PA
Sbjct: 338 TTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPA 397
Query: 740 EAPMPAEPAPPGPASPGGAPEPPAAARAGGSPTAVRSILTKERRP 784
P P P +P EP +PT +S T + P
Sbjct: 398 ----PTTTKEPAPTTP---KEPAPTTTKEPAPTTTKSAPTTPKEP 435
Score = 41.6 bits (96), Expect = 0.003
Identities = 55/202 (27%), Positives = 74/202 (36%), Gaps = 32/202 (15%)
Query: 430 AEVEAHNTVTSGTATTVIEIQVS---EQEPPSTDVPPSPEAGGTTGPWTSTTSEVPRPPE 486
A E T T G +T + ++ P+T P+P P TT E P P
Sbjct: 798 APKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAP---TTPETPPPTT 854
Query: 487 PSQGPSTTSSGGGTGPHPPSGTTLRPPTSSTPGGPPGAENSTSHQPATPGGDTAQTPKPG 546
TT+ T P +T P S P ENS P PG T +TP
Sbjct: 855 SEVSTPTTTKEPTTIHKSPDEST---PELSAEPTPKALENS----PKEPGVPTTKTP-AA 906
Query: 547 TSQPMPPGVGTSTSHQPATPSGGTAQTPEPGTSQPMPPSMGTSTSHQPATPGGGTAQTPE 606
T M +T+ + T TPE T+ P + T+T+ + T TA T +
Sbjct: 907 TKPEM------TTTAKDKTTERDLRTTPETTTAAP-KMTKETATTTEKTTESKITATTTQ 959
Query: 607 AGTSQPMPPGMGTSTSHQPTTP 628
TST+ Q TTP
Sbjct: 960 V-----------TSTTTQDTTP 970
>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
Length = 639
Score = 77.4 bits (189), Expect = 5e-14
Identities = 85/323 (26%), Positives = 103/323 (31%), Gaps = 62/323 (19%)
Query: 460 DVPPSPEAGGTTGPWTSTTSEVPRPPEPSQGPSTTSSGGGTGPHPP---SGTTLRPP--- 513
+ P G T+GP T+ + PRP P+ P S T PP SG + P
Sbjct: 322 EAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHG 381
Query: 514 -TSSTPGGPPGAENSTSHQ-PATPGG-------DTAQTPKPGTSQPMPPGVGTSTSHQPA 564
PGGP G +S H P+ GG P P QP PP + +Q
Sbjct: 382 MHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPM-----NQGP 436
Query: 565 TPSGGTAQTPEPGTSQPMPPSMGTSTSHQ-----PATPGGGTAQTPEAGTSQPMPPGMGT 619
P G P P G HQ P P G P + QP PP G
Sbjct: 437 HPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSG- 495
Query: 620 STSHQPTTPGGGTAQTPEPGTSQPMPLSKSTPSSGGGPSEDKRFSVVDMAALGGVLGALL 679
P P Q P P P P S S SS P + + A G +
Sbjct: 496 -----PLPPWQQQQQQPPP----PPPPSSSMASSTPLPWQQNTTTTTTSAGTGSI----- 541
Query: 680 LLALLGLAVLVHKHYGPRLKCCSGKAPEPQPQGFDNQAFLPDHKANWAPVPSPTHDPKPA 739
+ + + PQ QG P+P P P
Sbjct: 542 ------------PPWQQQQAAAAASPGAPQMQG----------NPTMVPLPPGVQPPLPP 579
Query: 740 EAPMPAEPAPPGPASPGGAPEPP 762
AP P P PPG A AP PP
Sbjct: 580 GAPPPPPPPPPGSAGMMYAPPPP 602
Score = 58.5 bits (140), Expect = 2e-08
Identities = 52/172 (30%), Positives = 62/172 (36%), Gaps = 33/172 (19%)
Query: 456 PPSTDVPPSPEAGGTTGPWTSTTSEVPRPPEPS------------QGPSTTSSGGGTGPH 503
PPS PP P G PW + P PP PS Q +TT++ GTG
Sbjct: 484 PPSGQPPPPPS--GPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSI 541
Query: 504 PPSGTTLRPPTSSTPGGPPGAENSTSHQPATPGGDTAQTPKPGTSQPMPPGVGTSTSHQP 563
PP + +++PG P N T P PG Q P P + P PP P
Sbjct: 542 PP-WQQQQAAAAASPGAPQMQGNPTM-VPLPPG---VQPPLPPGAPPPPP--------PP 588
Query: 564 ATPSGGTAQTPEPGTSQPMPPSMGTSTSHQPATPGGGTAQTPEAGTSQPMPP 615
S G P P PM PS + G G A P G PP
Sbjct: 589 PPGSAGMMYAPPPPPPPPMDPSNFVTMM------GMGVAGMPPFGMPPAPPP 634
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 77.4 bits (189), Expect = 5e-14
Identities = 90/340 (26%), Positives = 106/340 (31%), Gaps = 55/340 (16%)
Query: 455 EPPSTDVPPSPEAGGTTGPWTSTTSEVPRPPEPSQGPSTTSSGGGTGPHPPSGTTLRPPT 514
E S + PS AG GP ++ PP P P GG P P PP
Sbjct: 21 EDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGP------PPP 74
Query: 515 SSTPGGPPGAENSTSHQPATPGGDTAQTPKPGTSQPMPPGVGTSTSHQPATPSGGTAQTP 574
G PP + S S P +P G P G +QP P P G Q P
Sbjct: 75 GKPQGPPPQGDKSRS--PRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGP 132
Query: 575 EPGTSQPMPPSMGTSTSHQPATPGGGTAQTPEAGTSQPMPPGMGTSTSHQPTTPGGGTAQ 634
P PP G S P +P G P G +QP P P GG Q
Sbjct: 133 PPPGKPQGPPPQG-DKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQ 191
Query: 635 -TPEPGTSQ-PMPLSKSTPSSGGGPSEDKRFSVVDMAALGGVLGALLLLALLGLAVLVHK 692
P PG Q P P + SS P + + GG ++
Sbjct: 192 GPPPPGKPQGPPPQGDKSRSSQSPPGKPQ-----GPPPQGG-----------------NQ 229
Query: 693 HYGPRLKCCSGKAPEPQPQGFDN-QAFLPDHKANWAPV------------PSPTHDPKPA 739
GP GK P PQG + Q P K P P P
Sbjct: 230 PQGPPPP--PGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQ 287
Query: 740 EAPMPAEPAPPG-------PASPGGAPEPPAAARAGGSPT 772
E P P PP A P G P+ P GG P+
Sbjct: 288 EGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPS 327
Score = 76.3 bits (186), Expect = 1e-13
Identities = 81/329 (24%), Positives = 97/329 (29%), Gaps = 78/329 (23%)
Query: 454 QEPPSTDVPPSPEAGGTTGPWTSTTSEVPR-PPEPSQGPSTTSSGGGTGPHPPSGTTLRP 512
Q PP P P G S PR PP QGP GP PP G P
Sbjct: 69 QGPPPPGKPQGPPPQGDK-------SRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP 121
Query: 513 PTS--STPGGPPGA--------ENSTSHQPATPGGDTAQTPKPGTSQPMPPGVGTSTSHQ 562
P + P GPP + S P +P G P G +QP P
Sbjct: 122 PPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQG 181
Query: 563 PATPSGGTAQTPEPGTSQPMPPSMGTSTSHQPATPGGGTAQTPEAGTSQPMPPGMGTSTS 622
P G Q P P PP G + + PG P+ G +QP P
Sbjct: 182 PPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGG-NQPQGPPPPPGKP 240
Query: 623 HQPTTPGGGTAQTPEPGTSQPMPLSKSTPSSGGGPSEDKRFSVVDMAALGGVLGALLLLA 682
P GG Q P P P P+ GG S+
Sbjct: 241 QGPPPQGGNKPQGPPPPGKPQGP-----PAQGGSKSQ----------------------- 272
Query: 683 LLGLAVLVHKHYGPRLKCCSGKAPEPQPQGFDNQAFLPDHKANWAPVPSPTHDPKPAEAP 742
S ++P +PQG P + N +P P PA
Sbjct: 273 -------------------SARSPPGKPQG------PPQQEGN-----NPQGPPPPA-GG 301
Query: 743 MPAEPAPPGPASPGGAPEPPAAARAGGSP 771
P +P P P G P PP R P
Sbjct: 302 NPQQPQAPPAGQPQGPPRPPQGGRPSRPP 330
Score = 70.5 bits (171), Expect = 6e-12
Identities = 66/233 (28%), Positives = 77/233 (33%), Gaps = 41/233 (17%)
Query: 452 SEQEPPSTDVPPSPEAGGTT-GPWTSTTSEVPRPPEPSQGPSTTSSGGGTGPHPPSGTTL 510
S + PP P P+ G GP P PP QGP GP PP
Sbjct: 89 SPRSPPGKPQGPPPQGGNQPQGP--------PPPPGKPQGPPPQGGNRPQGPPPPGKPQG 140
Query: 511 RPPT---SSTPGGPPGAENSTSHQPATPGGDTAQTPKPGTSQPM-PPGVGTSTSHQPATP 566
PP S +P PPG P GG+ Q P P +P PP G P P
Sbjct: 141 PPPQGDKSRSPRSPPGKPQG----PPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPP 196
Query: 567 SGGTAQTP------------EPGTSQPMPPSMGTSTSHQPATPGGGTAQTPEAGTSQPMP 614
G Q P PG Q PP G P PG P+ G P
Sbjct: 197 --GKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGP 254
Query: 615 PGMGTSTSHQPTTPGGGTAQTPE--PGTSQPMPLSKST------PSSGGGPSE 659
P G P GG +Q+ PG Q P + P +GG P +
Sbjct: 255 PPPGKPQG--PPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQ 305
Score = 50.8 bits (120), Expect = 5e-06
Identities = 60/243 (24%), Positives = 75/243 (30%), Gaps = 52/243 (21%)
Query: 539 TAQTPKPGTSQPMPPGVGTSTSHQPATPSGGTAQTPEPGTSQPM-PPSMGTSTSHQPATP 597
+AQ SQ P + P+ G Q P P +P PP G + P P
Sbjct: 15 SAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPP 74
Query: 598 G--------GGTAQTPEAGTSQPM-PPGMGTSTSHQPTTPGGGTAQTPEPGTSQPMPLSK 648
G G +++P + +P PP G + P P G P G ++P
Sbjct: 75 GKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPP 134
Query: 649 STPSSGGGPSEDKRFSVVDMAALGGVLGALLLLALLGLAVLVHKHYGPRLKCCSGKAPEP 708
G P DK S PR GK P
Sbjct: 135 PGKPQGPPPQGDKSRS-------------------------------PRSP--PGKPQGP 161
Query: 709 QPQGFDNQAFLPDHKANWAPVPSPTHDPKPAEAPMPAEPAPPGPASPGGAPEPPAAARAG 768
PQG NQ P P P P P P P PPG P G P +R+
Sbjct: 162 PPQG-GNQPQGP------PPPPGKPQGPPPQGGKKPQGPPPPG--KPQGPPPQGDKSRSS 212
Query: 769 GSP 771
SP
Sbjct: 213 QSP 215
Score = 49.3 bits (116), Expect = 1e-05
Identities = 40/138 (28%), Positives = 46/138 (33%), Gaps = 23/138 (16%)
Query: 452 SEQEPPSTDVPPSPEAGGTT-GPWTSTTSEVPRPPEPSQGPSTTSSGGGTGPHPPSGTTL 510
S Q PP P P+ G GP P PP QGP GP PP
Sbjct: 211 SSQSPPGKPQGPPPQGGNQPQGP--------PPPPGKPQGPPPQGGNKPQGPPPPG---- 258
Query: 511 RPPTSSTPGGPPGAENSTSHQPATPGGDTAQTPKPGTSQPM--PPGVGTSTSHQPATPSG 568
P GPP S S +P G P+ + P PP G + A P+G
Sbjct: 259 ------KPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAG 312
Query: 569 GTAQTPEP--GTSQPMPP 584
P P G PP
Sbjct: 313 QPQGPPRPPQGGRPSRPP 330
Score = 30.4 bits (67), Expect = 7.2
Identities = 30/104 (28%), Positives = 38/104 (36%), Gaps = 22/104 (21%)
Query: 679 LLLALLGLAVL-----------VHKHYGPRLKCCSGKAPEPQPQGFDNQAFLPDHKANWA 727
+LL LL +A+L V + P L +G P PQG + P
Sbjct: 1 MLLILLSVALLALSSAQNLNEDVSQEESPSL--IAGNPQGPSPQGGNKPQGPP------- 51
Query: 728 PVPSPTHDPKPAEAPMPAEPAPPGPASPGGAPEPPAAARAGGSP 771
P P P P P P PPG P G P +R+ SP
Sbjct: 52 PPPGKPQGPPPQGGNKPQGPPPPG--KPQGPPPQGDKSRSPRSP 93
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 76.6 bits (187), Expect = 9e-14
Identities = 96/335 (28%), Positives = 111/335 (33%), Gaps = 51/335 (15%)
Query: 462 PPSPEAGGTTGPWTSTTSEVPRPPEPSQG------PSTTSSGGGTGPHPP-SGTTLRP-- 512
PP P G T P +T+ +P+PP P QG P G G P PP G + P
Sbjct: 878 PPPPPLPGMTVPTLPSTA-IPQPP-PLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLP 935
Query: 513 --PTSSTPGGPPGAENSTSHQPATPG-GDTAQTPKPGTSQPMPPGV-GTSTSHQPATPSG 568
P + P PP + P PG G P PG P PP + G P P
Sbjct: 936 PLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGA 995
Query: 569 GTAQTPE-PGTSQPMPPSM-GTSTSHQPATPGGGTAQTPE-AGTSQPMPPGM-GTSTSHQ 624
G P PG P PP + G P PG G P G P PP + G
Sbjct: 996 GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1055
Query: 625 PTTPGGGTAQTPE-PGTSQPMPLSKSTPSSGGG---PSEDKRFSVVDMAALGGVLGALLL 680
P PG G P PG P P P G G P + L GV G
Sbjct: 1056 PPLPGAGIPPPPPLPGAGIPPP----PPLPGAGIPPPPPLPGAGIPPPPPLPGV-GIPPP 1110
Query: 681 LALLGLAVLVHKHYGPRLKCCSGKAPEPQPQGFDNQAFLPDHKANWAPVPSPTHDPK--- 737
L G + P P P A +P P P+
Sbjct: 1111 PPLPGAGI-------------------PPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGI 1151
Query: 738 PAEAPMPAEPAPPGPASPG-GAPEPPAAARAGGSP 771
P P+P PP P PG G P PP G P
Sbjct: 1152 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPP 1186
Score = 75.1 bits (183), Expect = 3e-13
Identities = 94/341 (27%), Positives = 107/341 (31%), Gaps = 52/341 (15%)
Query: 449 IQVSEQEPPSTDVPPSPEAGGTTGPWTSTTSEVPRPPEPSQG--PSTTSSGGGTGPHPP- 505
+Q +E PP PP P AG P +P PP P G P G P PP
Sbjct: 902 LQGTEMLPPPP--PPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPL 959
Query: 506 --SGTTLRPPT--SSTPGGPPGAENSTSHQPATPG-GDTAQTPKPGTSQPMPPGV-GTST 559
+G L PP + P PP P PG G P PG P PP + G
Sbjct: 960 PGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1019
Query: 560 SHQPATPSGGTAQTPE-PGTSQPMPPSM-GTSTSHQPATPGGGTAQTPE-AGTSQPMPPG 616
P P G P PG P PP + G P PG G P G P PP
Sbjct: 1020 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1079
Query: 617 M-GTSTSHQPTTPGGGTAQTPE-PGTSQPMPLSKSTPSSGGGPSEDKRFSVVDMAALGGV 674
+ G P PG G P PG P P P G G + +
Sbjct: 1080 LPGAGIPPPPPLPGAGIPPPPPLPGVGIPPP----PPLPGAGIPPPPPLPGAGIPPPPPL 1135
Query: 675 LGALLLLALLGLAVLVHKHYGPRLKCCSGKAPEPQPQGFDNQAFLPDHKANWAPVPSPTH 734
GA + P P P A +P P
Sbjct: 1136 PGAGI----------------------------PPPPPLPRVGIPPPPPLPGAGIPPPPP 1167
Query: 735 DPK---PAEAPMPAEPAPPGPASPG-GAPEPPAAARAGGSP 771
P P P+P PP P PG G P PP AG P
Sbjct: 1168 LPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPP 1208
Score = 69.7 bits (169), Expect = 1e-11
Identities = 96/343 (27%), Positives = 112/343 (32%), Gaps = 50/343 (14%)
Query: 448 EIQVSEQEPPSTDVPPSPEAGGTTGPWTSTTSE------VPRPPEPSQGPSTTSSGGGTG 501
E VS S ++P P P T ++S VP PP P G + +
Sbjct: 842 EHSVSSAFKNSCNIPSPPPL-----PCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAI 896
Query: 502 PHPP--SGTTLRPPTSSTPGGPPGAENSTSHQPATPG-GDTAQTPKPGTSQPMPPGV-GT 557
P PP GT + PP P PGA P PG G P PG P PP + G
Sbjct: 897 PQPPPLQGTEMLPPP---PPPLPGA--GIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGA 951
Query: 558 STSHQPATPSGGTAQTPE-PGTSQPMPPSM-GTSTSHQPATPGGGTAQTPE-AGTSQPMP 614
+ P P G P PG P PP + G P PG G P G P P
Sbjct: 952 AIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1011
Query: 615 PGM-GTSTSHQPTTPGGGTAQTPE-PGTSQPMPLSKSTPSSGGGPSEDKRFSVVDMAALG 672
P + G P PG G P PG P P P G G +
Sbjct: 1012 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP----PPLPGAGIPPPPPLPGAGIPPPP 1067
Query: 673 GVLGALLLLALLGLAVLVHKHYGPRLKCCSGKAPEPQPQGFDNQAFLPDHKANWAPVPSP 732
+ GA G+ P L P P P P +P P
Sbjct: 1068 PLPGA-------GIPP------PPPLPGAGIPPPPPLP----GAGIPPPPPLPGVGIPPP 1110
Query: 733 THDPK---PAEAPMPAEPAPPGPASPG-GAPEPPAAARAGGSP 771
P P P+P PP P PG G P PP R G P
Sbjct: 1111 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPP 1153
Score = 61.6 bits (148), Expect = 3e-09
Identities = 62/197 (31%), Positives = 65/197 (32%), Gaps = 15/197 (7%)
Query: 462 PPSPEAGGTTGPWTSTTSEVPRPPEPSQG--PSTTSSGGGTGPHPPSGTTLRPPTSSTPG 519
PP P AG P P PP P G P G G P PP PP PG
Sbjct: 1034 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1093
Query: 520 G-----PPGAENSTSHQPATPG-GDTAQTPKPGTSQPMPPGV-GTSTSHQPATPSGGTAQ 572
PP P PG G P PG P PP + G P P G
Sbjct: 1094 AGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPP 1153
Query: 573 TPE-PGTSQPMPPSM-GTSTSHQPATPGGGTAQTPEA-GTSQPMPPGM-GTSTSHQPTTP 628
P PG P PP + G P PG G P G P PP + G P P
Sbjct: 1154 PPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLP 1213
Query: 629 GGGTAQTPEPGTSQPMP 645
G G P P P P
Sbjct: 1214 GMGIPPAPAP--PLPPP 1228
Score = 61.2 bits (147), Expect = 4e-09
Identities = 68/219 (31%), Positives = 76/219 (34%), Gaps = 24/219 (10%)
Query: 462 PPSPEAGGTTGPWTSTTSEVPRPPEPSQG--PSTTSSGGGTGPHPPSGTTLRPPTSSTPG 519
PP P AG P P PP P G P G G P PP PP PG
Sbjct: 1067 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPG 1126
Query: 520 G---PPGAENSTSHQPATP---GGDTAQTPKPGTSQPMPPGV-GTSTSHQPATPSGGTAQ 572
PP P P G P PG P PP + G P P G
Sbjct: 1127 AGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPP 1186
Query: 573 TPE-PGTSQPMPPSM-GTSTSHQPATPGGGTAQTPEAGTSQPMPPGMGTSTSHQPTTPGG 630
P PG P PP + G P PG G P + P+PP GT P P
Sbjct: 1187 PPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAP----APPLPP-PGTGIPPPPLLPVS 1241
Query: 631 GTAQTPEPGTSQ-PMP-----LSKSTPSS--GGGPSEDK 661
G P+ G+S P P L PS G G ++DK
Sbjct: 1242 GPPLLPQVGSSTLPTPQVCGFLPPPLPSGLFGLGMNQDK 1280
Score = 54.7 bits (130), Expect = 4e-07
Identities = 52/177 (29%), Positives = 58/177 (32%), Gaps = 24/177 (13%)
Query: 457 PSTDVPPSPEAGGTTGPWTSTTSEVPRPPEPSQG--PSTTSSGGGTGPHPPSGTTLRPPT 514
P +PP P G P P PP P G P G G P PP PP
Sbjct: 1103 PGVGIPPPPPLPGAGIP--------PPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPP 1154
Query: 515 SSTPGG-----PPGAENSTSHQPATPG-GDTAQTPKPGTSQPMPPGV-GTSTSHQPATPS 567
PG PP P PG G P PG P PP + G P P
Sbjct: 1155 PPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPG 1214
Query: 568 GGTAQTPEP-----GTSQPMPPSMGTSTSHQPATPGGGTAQTPE--AGTSQPMPPGM 617
G P P GT P PP + S G T TP+ P+P G+
Sbjct: 1215 MGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLPSGL 1271
Score = 47.0 bits (110), Expect = 7e-05
Identities = 69/287 (24%), Positives = 88/287 (30%), Gaps = 37/287 (12%)
Query: 500 TGPHPPSGTTLRPPTSSTPGGPPGAENSTSHQPATPGGDTAQTPKPGT-SQPMPPGVGTS 558
T P G PP PG PP + S + + P S + T
Sbjct: 746 TSPTEEGGVLTLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQ 805
Query: 559 TSHQPATPSG--GTAQTPEPGTSQPMPPSMGTSTSHQPATPGGGTAQTPEAGTSQPMP-- 614
+ QP P +A +PG+ P S TSH+ + + + P+P
Sbjct: 806 SISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSV-SSAFKNSCNIPSPPPLPCT 864
Query: 615 ------PGMGTSTSHQPTTPGGGTAQTPEPGTSQPMPLSKSTPSSGGGPSEDKRFSVVDM 668
PG+G P PG P QP PL + T P +
Sbjct: 865 ESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPL-QGTEMLPPPPPPLPGAGIPPP 923
Query: 669 AALGGVLGALLLLALLGLAVLVHKHYGPRLKCCSGKAPEPQPQGFDNQAFLPDHKANWAP 728
L G G L L L G + P P A P A
Sbjct: 924 PPLPGA-GILPLPPLPGAGI-------------------PPPPPLPGAAIPPPPPLPGAG 963
Query: 729 VPSPTHDPK---PAEAPMPAEPAPPGPASPG-GAPEPPAAARAGGSP 771
+P P P P P+P PP P PG G P PP AG P
Sbjct: 964 IPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1010
Score = 40.8 bits (94), Expect = 0.005
Identities = 82/344 (23%), Positives = 121/344 (35%), Gaps = 98/344 (28%)
Query: 560 SHQPATPSGGTAQTPEPGTSQPMP-----PSMGTSTSHQPATPG-----GGTAQTPEAGT 609
+ +PA P TA +P+PG + PS G + P +P + PE+
Sbjct: 229 AEEPAAPP--TAVSPQPGAFLGLDRFLLGPSGGAGEA--PGSPDTEQALSALSDLPESLA 284
Query: 610 SQPMPPGMGTSTSHQPTTPGG-GTAQTPEPGTSQPM----PLSKSTPSSGGGPSEDKRFS 664
++P P QP +PGG ++ P +QP P S + P GP E+
Sbjct: 285 AEPREP-------QQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEE---- 333
Query: 665 VVDMAALGGVLGALLLLALLGLAVLVHKHYGPRLKCCSGKAPEPQPQGFDNQAFLPD--- 721
AA V GA G + A E P+G + + P+
Sbjct: 334 ----AAGAPVRGA-----------------GDTDEEGEEDAFEDAPRGSPGEEWAPEVGE 372
Query: 722 ---HKANWAPVPSPTHDPKPAEAPMPAEPAP------PGP--------------ASPGGA 758
+ P PA A +P PAP P P +SP +
Sbjct: 373 DAPQRLGEEPEEEAQGPDAPAAASLPGSPAPSQRCFKPYPLITPCYIKTTTRQLSSPNHS 432
Query: 759 PEP-----------PAAARAGGSPTAVRSILT--KERRPEGGYKA-----VWFGEDIGTE 800
P P + + GS TA+ S+ K+ R +GG A + E++G
Sbjct: 433 PSQSPNQSPRIKRRPEPSLSRGSRTALASVAAPAKKHRADGGLAAGLSRSADWTEELGAR 492
Query: 801 ADVVVLNAPTLDVDGASDSGSGDEGEGAGRGGGPYDAPGGDDSY 844
V +A L+ ASDSG G A + G AP D +
Sbjct: 493 TPRVGGSAHLLERGVASDSGGGVSPALAAKASG---APAAADGF 533
Score = 33.9 bits (76), Expect = 0.65
Identities = 38/132 (28%), Positives = 45/132 (34%), Gaps = 26/132 (19%)
Query: 457 PSTDVPPSPEAGGTTGPWTSTTSEVPRPPEPSQGPSTTSSGGGTGPHPPSGTTLRPPTSS 516
P +PP P G P P PP P G G P PP PP +
Sbjct: 1180 PGVGIPPPPPLPGVGIP--------PPPPLP---------GAGIPPPPPLPGMGIPPAPA 1222
Query: 517 TPGGPPGAENSTSHQPATPGGDTAQTPKPGTSQ-PMPPGVGTSTSHQPATPSG--GTAQT 573
P PPG P P P+ G+S P P G P PSG G
Sbjct: 1223 PPLPPPG--TGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFL---PPPLPSGLFGLGMN 1277
Query: 574 PEPGT-SQPMPP 584
+ G+ QP+ P
Sbjct: 1278 QDKGSRKQPIEP 1289
>gi|222352122 hypothetical protein LOC284297 [Homo sapiens]
Length = 1573
Score = 75.9 bits (185), Expect = 1e-13
Identities = 103/407 (25%), Positives = 140/407 (34%), Gaps = 77/407 (18%)
Query: 437 TVTSGTATTVIEIQVSEQEPPSTDVPPSPEAGGTTGPWTSTTSEVPRPPEPSQGPSTTSS 496
T T + V + + ++ P +D P + T P++ST SE R P+PS P T++
Sbjct: 1099 TSDPSTPSEVTSLSPTSEQVPESDTTPDLD----TTPYSSTVSEYSRSPDPSPSPHPTTT 1154
Query: 497 GGGTGPHPPSGTTLRP------PTSSTPGGPPG----------AENSTSHQPATPGGDTA 540
T P TTL P PT+ P P + +T+ QP T +
Sbjct: 1155 PDPTMAPDPI-TTLNPTVTPHFPTTPHPTTTPHPTTITHSTMIPDPTTTPQPFTTITHST 1213
Query: 541 QTPKPGTS-QPMPPGVGTSTSHQPATPSGGTAQTPEPGTSQPMPPSMGTSTSHQPATPGG 599
P P T+ QP T+T H TP T P T M P +T+ QP T
Sbjct: 1214 MIPDPTTTPQPFTTMQPTTTPHS-TTPHPTTTPHPTTITHSTMIPD--PTTTPQPFTTMQ 1270
Query: 600 GTAQTPEAGTSQPMPPGMGTSTSHQPTTPGGGTAQTPEPGTSQPMPLSKSTPSSGGGPS- 658
T T P T+T H TTP TP+P T+ P P + P++ P+
Sbjct: 1271 PTTMPHPTTTPHPTTTPHPTTTPHPTTTP--HPTMTPDP-TTTPYPTTTPDPTTTPHPTT 1327
Query: 659 -EDKRFSVVDMAALGGVLGALLLLALLGLAVLVHKH-----YGPRLKCCSGKAP--EPQP 710
+ V+ +L LG L L V H P + + P EP P
Sbjct: 1328 PDPSSTPVITTVSLPTSLGTELSSPTLAPTVKPSLHPQLTFTAPAPHTSTSQIPTLEPSP 1387
Query: 711 ---------------QGFDNQAFLPDHKANWAPVPSPTHDP------------------- 736
+ F P + P PTH P
Sbjct: 1388 ALESSPSRSSTATSMDPLSTEDFKPPRSQSPNLTPPPTHTPHSASDLTVSPDPLLSPTAH 1447
Query: 737 ---KPAEAPMPAEPAP---PGPASPGGAPEPPAAARAGGSPTAVRSI 777
P P+ P P PGP P AP PP A P V +
Sbjct: 1448 PLDHPPLDPLTLGPTPGQSPGPHGPCVAPTPPVRVMACEPPALVELV 1494
Score = 55.1 bits (131), Expect = 3e-07
Identities = 84/344 (24%), Positives = 114/344 (33%), Gaps = 83/344 (24%)
Query: 451 VSEQEPPSTDVPPSPEAGGTTGPWTSTTSEV------PRPPEPSQGPSTTSSGGGTGPHP 504
++E P + + P+ AG T P + T V PR P P + P ++ T P
Sbjct: 948 LAEGTPTAGKLGPTLGAGTTRSPGSPPTLRVHGDTGSPRKPWPERRPPRPAATR-TAPPT 1006
Query: 505 PSGTTLRPPTSSTPGGPPGAENSTSHQPATPGG---DTAQTPKPGTSQPMPPGVG----- 556
PS P S++PG P A S S + TP A + P TS P P
Sbjct: 1007 PS-----PGPSASPGPPGPALTSDSSRELTPHSALTSEATSDAPDTSPPTPDPASRTNPD 1061
Query: 557 ---TSTSHQPATPSGGT--AQTPEPGTSQPMP-PSMGTSTSHQPATPGGGTA------QT 604
TS +TP A TPEP P P P++ + P+TP T+ Q
Sbjct: 1062 LILTSPDFALSTPDSSVVPALTPEPS---PTPLPTLPKELTSDPSTPSEVTSLSPTSEQV 1118
Query: 605 PEAGTSQPMPPGMGTSTSHQPTTPGGGT----AQTPEPGTSQPMPLSKSTPSSGGGPSED 660
PE+ T T TTP T +++P+P S P P + P+ P
Sbjct: 1119 PESDT-----------TPDLDTTPYSSTVSEYSRSPDPSPS-PHPTTTPDPTMAPDP--- 1163
Query: 661 KRFSVVDMAALGGVLGALLLLALLGLAVLVHKHYGPRLKCCSGKAPEPQPQGFDNQAFLP 720
+ L V H P P P + +P
Sbjct: 1164 --------------------ITTLNPTVTPHFPTTPH------PTTTPHPTTITHSTMIP 1197
Query: 721 DHKANWAPVPSPTHD---PKPAEAPMPAEPAPPGPASPGGAPEP 761
D P + TH P P P P P P P
Sbjct: 1198 DPTTTPQPFTTITHSTMIPDPTTTPQPFTTMQPTTTPHSTTPHP 1241
Score = 53.9 bits (128), Expect = 6e-07
Identities = 63/236 (26%), Positives = 89/236 (37%), Gaps = 22/236 (9%)
Query: 434 AHNTVTSGTATTVIEIQVSEQEPPSTD-VPPSPEAGGTTG---PWTSTTSEVPRPPE--P 487
A T T+G + + + + S+ + P+ G G PWT T E P
Sbjct: 894 AKGTTTAGVPGHTLPWRTTRRPGSSSPAIRRLPDTGSKDGYKLPWTWDTPSGRGLAEGTP 953
Query: 488 SQGPSTTSSGGGTGPHPPSGTTLRPPTSSTPGGPPGAENSTSHQPATPGGDTAQTPKPGT 547
+ G + G GT P S TLR + P E AT +P P
Sbjct: 954 TAGKLGPTLGAGTTRSPGSPPTLRVHGDTGSPRKPWPERRPPRPAATRTAPPTPSPGPSA 1013
Query: 548 SQPMPPGVG-TSTSHQPATPSG---GTAQTPEPGTSQPMPPSMGTSTSHQPATPGGGTAQ 603
S P PPG TS S + TP A + P TS P P + T
Sbjct: 1014 S-PGPPGPALTSDSSRELTPHSALTSEATSDAPDTSPPTPDPASRTNPDLILTSPDFALS 1072
Query: 604 TPEAG-----TSQPMP---PGMGTSTSHQPTTPGGGTAQTPEPGTSQPMPLSKSTP 651
TP++ T +P P P + + P+TP T+ +P TS+ +P S +TP
Sbjct: 1073 TPDSSVVPALTPEPSPTPLPTLPKELTSDPSTPSEVTSLSP---TSEQVPESDTTP 1125
>gi|148886692 FAT tumor suppressor homolog 3 [Homo sapiens]
Length = 4557
Score = 75.5 bits (184), Expect = 2e-13
Identities = 98/381 (25%), Positives = 150/381 (39%), Gaps = 56/381 (14%)
Query: 47 EPLVDIHVPEGQEVT--LGALS-----TPFAFRIQGNQ-------------LFLNVTPDY 86
EP + V E VT +G +S TP F I G + + D
Sbjct: 1364 EPFYNFTVMESDRVTEIVGVVSVQPANTPLWFDIVGGNFDSAFDAEKGVGTIVIAKPLDA 1423
Query: 87 EEKSLLEAQLLCQSGGTLVTQLRVFVSVLDVNDNAPEFPFKTKEIRVEEDTKVNSTVIPE 146
E++S+ + + GT V +VF+ VLD NDN PEF ++ + ED V+P+
Sbjct: 1424 EQRSIYNMSVEV-TDGTNVAVTQVFIKVLDNNDNGPEFSQPNYDVTISED------VLPD 1476
Query: 147 T---QLQAEDRDKDDILFYTLQEMTAGASDYFSLVSVNRPALRLDRPLDFYERPNMTFWL 203
T Q++A DRD+ L YT+ S + + L LD + +
Sbjct: 1477 TEILQIEATDRDEKHKLSYTVHSSIDSISMRKFRIDPSTGVLYTAERLDHEAQDKHILNI 1536
Query: 204 LVRDTPGENVEPSHTATATLVLNVVPADLRPPWFLPCTFSDGYVCIQAQYHGAVPTGHIL 263
+VRD P A +++NV A+ P+F Y +V L
Sbjct: 1537 MVRD----QEFPYRRNLARVIVNVEDANDHSPYF-----------TNPLYEASVFESAAL 1581
Query: 264 PSPLVLRPGPIYAEDGDRGINQPIIYSIFRGNVNGTFIIHPDSGNLTVARSVPSPMT--- 320
S ++ + A D D+G N +IY+I GN F I P G +T+ + P T
Sbjct: 1582 GSAVL----QVTALDKDKGENAELIYTIEAGNTGNMFKIEPVLGIITICKE-PDMTTMGQ 1636
Query: 321 FLLLVKGQQADLARYSVTQ-VTVEAVAAAGSPPRFPQRLYRGTVARGAGAGVVVKDAAAP 379
F+L +K S T V + + S P+F + Y+ V G V +A
Sbjct: 1637 FVLSIKVTDQGSPPMSATAIVRISVTMSDNSHPKFIHKDYQAEVNENVDIGTSVILISAI 1696
Query: 380 SQPLRIQAQDPEFSDLNSAIT 400
SQ I + + D+N T
Sbjct: 1697 SQSTLI--YEVKDGDINGIFT 1715
Score = 68.9 bits (167), Expect = 2e-11
Identities = 91/370 (24%), Positives = 154/370 (41%), Gaps = 40/370 (10%)
Query: 9 PPLLFTGLLVRPPGTMAQAQYCS-VNKDI-FEVEENTNVTEPLVDIHVPEGQ----EVTL 62
PP+ T + VR TM+ + ++KD EV EN ++ ++ I EV
Sbjct: 1649 PPMSATAI-VRISVTMSDNSHPKFIHKDYQAEVNENVDIGTSVILISAISQSTLIYEVKD 1707
Query: 63 GALSTPFAFRIQGNQLFLNVTPDYEEKSLLEAQLLCQSGGTLVTQLRVFVSVLDVNDNAP 122
G ++ F + DYE S + + + + + V + ++D NDNAP
Sbjct: 1708 GDINGIFTINPYSGVITTQKALDYERTSSYQLIIQATNMAGMASNATVNIQIVDENDNAP 1767
Query: 123 EFPFKTKEIRVEEDTKVNSTV----IPETQLQAEDRD--KDDILFYTLQEMTAGASDYFS 176
F F + E +NS V ++A D D ++ +L Y + E TA F
Sbjct: 1768 VFLFSQYSGSLSEAAPINSIVRSLDNSPLVIRATDADSNRNALLVYQIVESTA---KKFF 1824
Query: 177 LVSVNRPALRLDRPLDFYERPNMTFWLLVRDTPGENVEPSHTATATLVLNVVPADL--RP 234
V + A+R LD + F + VRD+ P TA + + +N+ D+ P
Sbjct: 1825 TVDSSTGAIRTIANLDHETIAHFHFHVHVRDSG----SPQLTAESPVEVNIEVTDVNDNP 1880
Query: 235 PWFLPCTFSDGYVCIQAQYHGAVPTGHILPSPLVLRPGPIYAEDGDRGINQPIIYSIFRG 294
P F F T +LP+ + + + A D D + + YS+ G
Sbjct: 1881 PVFTQAVFE---------------TILLLPTYVGVEVLKVSATDPDSEVPPELTYSLMEG 1925
Query: 295 NVNGTFIIHPDSGNLTVARSVPSPMTFLLLVKGQQADLARYSVTQVTVEAVAAAGSPPRF 354
+++ F+I +SG LT+ + S ++L+VK +D YS + VT+ A S F
Sbjct: 1926 SLD-HFLIDSNSGVLTIKNNNLSKDHYMLIVK--VSDGKFYSTSMVTIMVKEAMDSGLHF 1982
Query: 355 PQRLYRGTVA 364
Q Y +++
Sbjct: 1983 TQSFYSTSIS 1992
Score = 62.4 bits (150), Expect = 2e-09
Identities = 102/428 (23%), Positives = 172/428 (40%), Gaps = 61/428 (14%)
Query: 59 EVTLGALSTPFAFRIQGNQLFLNVTPDYEEKSL------LEAQLLCQSGGTLVTQLRVFV 112
EVT L+ F I + + V + +S +EA+ +SG L + + + V
Sbjct: 865 EVTYSVLTDTQQFAINSSTGIVYVADQLDRESKANYSLKIEARDKAESGQQLFSVVTLKV 924
Query: 113 SVLDVNDNAPEFPFKTKEIRVEEDTKVNSTVIPETQLQAEDRDKDDILFYTLQEMTAGAS 172
+ DVND +P F + ++V ED V TVI + D + Y+L +
Sbjct: 925 FLDDVNDCSPAFIPSSYSVKVLEDLPV-GTVIAWLETHDPDLGLGGQVRYSL------VN 977
Query: 173 DYFSLVSVNRP--ALRLDRPLDFYERPNMTFWLLVRDTPGENVEPSHTATATLVLNVVPA 230
DY +++ A+RL + LD+ ++ + +D G V S + + + V
Sbjct: 978 DYNGRFEIDKASGAIRLSKELDYEKQQFYNLTVRAKD-KGRPVSLSSVSFVEVEVVDVNE 1036
Query: 231 DLRPPWFLPCTFSDGYVCIQAQYHGAVPTGHILPSPLVLRPGPIYAEDGDRGINQPIIYS 290
+L P+ F D V + + + T + + A D D G + I YS
Sbjct: 1037 NLHTPY-----FPDFAVVGSVKENSRIGTSVL----------QVTARDEDSGRDGEIQYS 1081
Query: 291 IFRGNVNGTFIIHPDSGNLTVARSVPSPMT---FLLLVKGQQADLARYSVTQVTVEAVAA 347
I G+ G F I +SG +T A + +L + + + YS +V +E
Sbjct: 1082 IRDGSGLGRFSIDDESGVITAADILDRETMGSYWLTVYATDRGVVPLYSTIEVYIEVEDV 1141
Query: 348 AGSPPRFPQRLYRGTVARGAGAGVVVKDAAAPSQPLRIQAQDPEFSDLNSAITYRITN-- 405
+ P + +Y V + V V ++IQA+DP+ S N +TYRIT+
Sbjct: 1142 NDNAPLTSEPIYYPVVMENSPKDVSV---------IQIQAEDPD-SSSNEKLTYRITSGN 1191
Query: 406 -HSHFRMEGEVVLTTTT-----LAQAGAFYAEVEAHNTVTSG-----TATTVIEIQVSEQ 454
+ F + + L TTT Q + EV TVT G +T + +QV ++
Sbjct: 1192 PQNFFAINIKTGLITTTSRKLDREQQAEHFLEV----TVTDGGPSPKQSTIWVVVQVLDE 1247
Query: 455 EPPSTDVP 462
P
Sbjct: 1248 NDNKPQFP 1255
Score = 62.0 bits (149), Expect = 2e-09
Identities = 78/311 (25%), Positives = 135/311 (43%), Gaps = 42/311 (13%)
Query: 101 GGTLVTQLRVFVSVLDVNDNAPEFPFKTKEIRVEEDTKVNSTVIPETQLQAEDRD--KDD 158
GG Q + + + DVNDN P F V E+T + + T++QA D D +
Sbjct: 3108 GGGRFCQSNIHLILEDVNDNPPVFSSDHYNTCVYENTATKALL---TRVQAVDPDIGINR 3164
Query: 159 ILFYTLQEMTAGASDYFSLVSVNRPALRLDRPLDFYERPNMTFWLLVRD-TPGENVEPSH 217
+ Y+L + G FS+ S + + L++PLD ++ + + D +PG+++
Sbjct: 3165 KVVYSLADSAGGV---FSIDS-SSGIIILEQPLDREQQSSYNISVRATDQSPGQSL---- 3216
Query: 218 TATATLVLNVVPADLRPPWFLPCTFSDGYVCIQAQYHGAVPTGHILPSPLVLRPGPIYAE 277
++ T+ + V+ + PP F + Y VP P VL ++A
Sbjct: 3217 SSLTTVTITVLDINDNPPVF-----------ERRDYLVTVPE-DTSPGTQVL---AVFAT 3261
Query: 278 DGDRGINQPIIYSIFRGNVNGTFIIHPDSGNLTVARSVPSPM--TFLLLVKGQQADL-AR 334
D G N I Y I GN G F I+P +G ++V+ + + F L+V+ + A
Sbjct: 3262 SKDIGTNAEITYLIRSGNEQGKFKINPKTGGISVSEVLDYELCKRFYLVVEAKDGGTPAL 3321
Query: 335 YSVTQVTVEAVAAAGSPPRFPQRLYRGTVARGAGAGVVVKDAAAPSQPLRIQAQDPEFSD 394
+V V + +PP+F Q +Y + V+ +DA + + A+D + S
Sbjct: 3322 SAVATVNINLTDVNDNPPKFSQDVY---------SAVISEDALVGDSVILLIAEDVD-SQ 3371
Query: 395 LNSAITYRITN 405
N I + I N
Sbjct: 3372 PNGQIHFSIVN 3382
Score = 60.1 bits (144), Expect = 8e-09
Identities = 85/342 (24%), Positives = 138/342 (40%), Gaps = 28/342 (8%)
Query: 39 VEENTNVTEPLVDIHV--PEGQEVTLGALS-TPFA-FRIQGNQLFLNVTP--DYEEKSLL 92
V E+ + P++ I+ PEGQ + + PF F I + L V DYE S
Sbjct: 2195 VNEDIRMNTPILSINATSPEGQGIIYIIIDGDPFKQFNIDFDTGVLKVVSPLDYEVTSAY 2254
Query: 93 EAQLLCQSGGTLV-TQLRVFVSVLDVNDNAPEFPFKTKEIRVEEDTKVNSTVIPETQLQA 151
+ + T ++ V + V DVNDN P F T + E + + + V+ + A
Sbjct: 2255 KLTIRASDALTGARAEVTVDLLVNDVNDNPPIFDQPTYNTTLSEASLIGTPVLQVVSIDA 2314
Query: 152 EDRDKDDILFYTLQEMTAGASDYFSLVSVNRPALRLDRPLDFYERPNMTFWLLVRDTPGE 211
D + + ++ Y + + T ++DYF + S + L R LD + T L VR +
Sbjct: 2315 -DSENNKMVHYQIVQDTYNSTDYFHIDSSSGLILTA-RMLDHELVQHCT--LKVRSI--D 2368
Query: 212 NVEPSHTATATLVLNVVPADLRPPWFLPCTFSDGYVCIQAQYHGAVPTGHILPSPLVLRP 271
+ PS ++ + + + + PP F + + YV A P GH +
Sbjct: 2369 SGFPSLSSEVLVHIYISDVNDNPPVFNQLIY-ESYVSELA------PRGHFVTC------ 2415
Query: 272 GPIYAEDGDRGINQPIIYSIFRGNVNGTFIIHPDSGNLTVARSVPSPMTFLLLVKGQQAD 331
+ A D D + YSI GN +F++ SG +T++ M L + +D
Sbjct: 2416 --VQASDADSSDFDRLEYSILSGNDRTSFLMDSKSGVITLSNHRKQRMEPLYSLNVSVSD 2473
Query: 332 LARYSVTQVTVEAVAAAGSPPRFPQRLYRGTVARGAGAGVVV 373
S QV + + A P F Q Y V AG V
Sbjct: 2474 GLFTSTAQVHIRVLGANLYSPAFSQSTYVAEVRENVAAGTKV 2515
Score = 50.4 bits (119), Expect = 7e-06
Identities = 94/388 (24%), Positives = 143/388 (36%), Gaps = 54/388 (13%)
Query: 85 DYEEKSLLEAQLLCQSGGTLVTQLRVFVSVLDVNDNAPEFPFKTKEIRVEEDTKVNSTVI 144
D EE+ + + + G VTQ V VSV DVNDN+P + ED N ++
Sbjct: 2991 DREEQDIYFLNITA-TDGLFVTQAMVEVSVSDVNDNSPVCDQVAYTALLPEDIPSNKIIL 3049
Query: 145 PETQLQAEDRDKDDILFYTLQEMTAGASDYFSLVSVNRPALRLDRPLDFYERPNMTFWLL 204
++ A+D D + +G S++F + L+ LD P + L+
Sbjct: 3050 ---KVSAKDADIGSNGYIRYSLYGSGNSEFF--LDPESGELKTLALLDRERIP--VYSLM 3102
Query: 205 VRDTPGENVEPSHTATATLVLNVVPADLRPPWFLPCTFSDGY-VCIQAQYHGAVPTGHIL 263
+ T G + + L + + PP F SD Y C+ +
Sbjct: 3103 AKATDGGG----RFCQSNIHLILEDVNDNPPVFS----SDHYNTCVYE---------NTA 3145
Query: 264 PSPLVLRPGPIYAEDGDRGINQPIIYSIFRGNVNGTFIIHPDSGNLTVA----RSVPSPM 319
L+ R + A D D GIN+ ++YS+ + G F I SG + + R S
Sbjct: 3146 TKALLTR---VQAVDPDIGINRKVVYSL-ADSAGGVFSIDSSSGIIILEQPLDREQQSSY 3201
Query: 320 TFLLLVKGQQADLARYSVTQVTVEAVAAAGSPPRFPQRLYRGTVARGAGAGVVVKDAAAP 379
+ Q + S+T VT+ + +PP F +R Y TV G V A
Sbjct: 3202 NISVRATDQSPGQSLSSLTTVTITVLDINDNPPVFERRDYLVTVPEDTSPGTQVLAVFAT 3261
Query: 380 SQPLRIQAQDPEFSDLNSAITYRI---TNHSHFRME----GEVVLTTTTLAQAGAFYAEV 432
S+ + N+ ITY I F++ G V FY V
Sbjct: 3262 SKDI----------GTNAEITYLIRSGNEQGKFKINPKTGGISVSEVLDYELCKRFYLVV 3311
Query: 433 EAHNTVT---SGTATTVIEIQVSEQEPP 457
EA + T S AT I + PP
Sbjct: 3312 EAKDGGTPALSAVATVNINLTDVNDNPP 3339
Score = 47.0 bits (110), Expect = 7e-05
Identities = 65/280 (23%), Positives = 110/280 (39%), Gaps = 34/280 (12%)
Query: 101 GGTLVTQLRVFVSVLDVNDNAPEFPFKTKEIRVEEDTKVNSTVIPETQLQAEDRDKDDIL 160
G +L + V ++VLD+NDN P F + + V EDT P TQ+ A DI
Sbjct: 3213 GQSLSSLTTVTITVLDINDNPPVFERRDYLVTVPEDTS------PGTQVLAVFATSKDI- 3265
Query: 161 FYTLQEMT----AGASDYFSLVSVNRPALRLDRPLDFYERPNMTFWLLVRDTPGENVEPS 216
T E+T +G ++ + + LD+ F+L+V G P+
Sbjct: 3266 -GTNAEITYLIRSGNEQGKFKINPKTGGISVSEVLDY--ELCKRFYLVVEAKDGGT--PA 3320
Query: 217 HTATATLVLNVVPADLRPPWFLPCTFSDGYVCIQAQYHGAVPTGHILPSPLVLRPGPIYA 276
+A AT+ +N+ + PP F Q Y + ++ ++L + A
Sbjct: 3321 LSAVATVNINLTDVNDNPPKF-----------SQDVYSAVISEDALVGDSVIL----LIA 3365
Query: 277 EDGDRGINQPIIYSIFRGNVNGTFIIHPDSGNLTVARSVPSPMT--FLLLVKGQQADL-A 333
ED D N I +SI G+ + F + P G + V + + + LLV+ + + A
Sbjct: 3366 EDVDSQPNGQIHFSIVNGDRDNEFTVDPVLGLVKVKKKLDRERVSGYSLLVQAVDSGIPA 3425
Query: 334 RYSVTQVTVEAVAAAGSPPRFPQRLYRGTVARGAGAGVVV 373
S V ++ + P F Y + G +
Sbjct: 3426 MSSTATVNIDISDVNDNSPVFTPANYTAVIQENKPVGTSI 3465
Score = 44.3 bits (103), Expect = 5e-04
Identities = 66/304 (21%), Positives = 113/304 (37%), Gaps = 81/304 (26%)
Query: 110 VFVSVLDVNDNAPEFPFKTKEIRV-EEDTKVNSTVIPETQLQAEDRDK------------ 156
V V VLD NDN P+FP K +I++ E D K P + A DRD+
Sbjct: 1240 VVVQVLDENDNKPQFPEKVYQIKLPERDRKKRGE--PIYRAFAFDRDEGPNAEISYSIVD 1297
Query: 157 --DDILFY---------TLQEMTAGASDYFSLVSVNRPALRLDRPLDFYERPNMTFWLLV 205
DD F+ + ++ TAG+ D ++ +V
Sbjct: 1298 GNDDGKFFIDPKTGMVSSRKQFTAGSYDILTIKAV------------------------- 1332
Query: 206 RDTPGENVEPSHTATATLVLNVVPADLRPPWFLPCTFSDGYVCIQAQYHGAVPTGHILPS 265
+N P ++TA L + + PP +P TF + + Y+ V
Sbjct: 1333 -----DNGRPQKSSTARLHIEWIKKP--PPSPIPLTFDEPF------YNFTVMESD---- 1375
Query: 266 PLVLRPGPIYAEDGDRGINQPIIYSIFRGNVNGTFIIHPDSGNLTVARSVPSPMTFLLLV 325
R I + N P+ + I GN + F G + +A+ + + + +
Sbjct: 1376 ----RVTEIVGVVSVQPANTPLWFDIVGGNFDSAFDAEKGVGTIVIAKPLDAEQRSIYNM 1431
Query: 326 KGQQADLARYSVTQVTVEAVAAAGSPPRFPQRLYRGTVARGAGAGVVVKDAAAPSQPLRI 385
+ D +VTQV ++ + + P F Q Y T++ +D ++ L+I
Sbjct: 1432 SVEVTDGTNVAVTQVFIKVLDNNDNGPEFSQPNYDVTIS---------EDVLPDTEILQI 1482
Query: 386 QAQD 389
+A D
Sbjct: 1483 EATD 1486
Score = 43.1 bits (100), Expect = 0.001
Identities = 74/370 (20%), Positives = 145/370 (39%), Gaps = 50/370 (13%)
Query: 106 TQLRVFVSVLDVNDNAPEFPFKTKEIRVEEDTKVNSTVIPETQLQAEDRDKDDILFYTLQ 165
+++ V + + +VNDN+P F + + D V + T + A D D+ +++ Y
Sbjct: 560 SEVNVTIRIGNVNDNSPLFEKVACQGVISYDFPVGGHI---TAVSAIDIDELELVKY--- 613
Query: 166 EMTAGASDYFSLVSVNRPALRLDRPLDFYERPNMTFWLLVRDTPGENVEPSHTATATLVL 225
++ +G F ++ + L+L + L N F L + T GEN+ + +++
Sbjct: 614 KIISGNELGFFYLNPDSGVLQLKKSLTNSGIKNGNFALRITATDGENLADPMSINISVLH 673
Query: 226 NVVPAD------------------LRPPWFLPCTFSDGYVCIQAQYHGAVPTGHILPSPL 267
V + ++ DG++ + PS +
Sbjct: 674 GKVSSKSFSCRETRVAQKLAEKLLIKAKANGKLNLEDGFLDFYSINRQGPYFDKSFPSDV 733
Query: 268 VLRPG--------PIYAEDGDRGINQPIIYSIFRGNVNGTFIIHPDSGNLTVARSVPSPM 319
++ I A D D G N ++++I GN + F I ++G L V +
Sbjct: 734 AVKEDLPVGANILKIKAYDADSGFNGKVLFTISDGNTDSCFNIDMETGQLKVLMPMDREH 793
Query: 320 TFLLLVKGQQADLA---RYSVTQVTVEAVAAAGSPPRFPQRLYRGTVARGAGAGVVVKDA 376
T L L+ DL + S +T+ A + P F Q Y + +G G +
Sbjct: 794 TDLYLLNITIYDLGNPQKSSWRLLTINVEDANDNSPVFIQDSYSVNILESSGIGTEI--- 850
Query: 377 AAPSQPLRIQAQDPEFSDLNSAITYRI-TNHSHFRME---GEVVLTTTTLAQAGAFYA-E 431
++++A+D + N +TY + T+ F + G V + ++ A Y+ +
Sbjct: 851 ------IQVEARDKDLGS-NGEVTYSVLTDTQQFAINSSTGIVYVADQLDRESKANYSLK 903
Query: 432 VEAHNTVTSG 441
+EA + SG
Sbjct: 904 IEARDKAESG 913
Score = 43.1 bits (100), Expect = 0.001
Identities = 58/226 (25%), Positives = 92/226 (40%), Gaps = 26/226 (11%)
Query: 104 LVTQLRVFVSVLDVNDNAPEFPFKTKEIRVEEDTKVNSTVIPETQLQAEDRDKDDILFYT 163
L + + V++ V DVNDNAP V E++ + +VI Q+QAED D T
Sbjct: 1128 LYSTIEVYIEVEDVNDNAPLTSEPIYYPVVMENSPKDVSVI---QIQAEDPDSSSNEKLT 1184
Query: 164 LQEMTAGASDYFSLVSVNRPALRLDRPLDFYERPNMTFWLLVRDTPGENVEPSHTATATL 223
+ + ++F++ R LD ++ + V D G + + S T +
Sbjct: 1185 YRITSGNPQNFFAINIKTGLITTTSRKLDREQQAEHFLEVTVTDG-GPSPKQS---TIWV 1240
Query: 224 VLNVVPADLRPPWFLPCTFSDGYVCIQAQYHGAVPTGHILPSPLVLRPGPIY---AEDGD 280
V+ V+ + P F + Y +P R PIY A D D
Sbjct: 1241 VVQVLDENDNKPQFP-----------EKVYQIKLPE-----RDRKKRGEPIYRAFAFDRD 1284
Query: 281 RGINQPIIYSIFRGNVNGTFIIHPDSGNLTVARSVPSPMTFLLLVK 326
G N I YSI GN +G F I P +G ++ + + +L +K
Sbjct: 1285 EGPNAEISYSIVDGNDDGKFFIDPKTGMVSSRKQFTAGSYDILTIK 1330
Score = 41.6 bits (96), Expect = 0.003
Identities = 81/369 (21%), Positives = 145/369 (39%), Gaps = 54/369 (14%)
Query: 112 VSVLDVNDNAPEFPFKTKEIRVEEDTKVNSTVIPETQLQAEDRDKDDILFYTLQEMTAGA 171
++V D NDN+P F + + + E + + + +I Q++A D+D T +T
Sbjct: 819 INVEDANDNSPVFIQDSYSVNILESSGIGTEII---QVEARDKDLGSNGEVTYSVLT--D 873
Query: 172 SDYFSLVSVNRPALRLDRPLDFYERPNMTFWLLVRDTPGENVEPSHTATATLVLNVVPAD 231
+ F++ S D+ LD + N + + RD E + + L V D
Sbjct: 874 TQQFAINSSTGIVYVADQ-LDRESKANYSLKIEARD----KAESGQQLFSVVTLKVFLDD 928
Query: 232 LR--PPWFLPCTFSDGYVCIQAQYHGAVPTGHILPSPLVLRPGPIYAEDGDRGINQPIIY 289
+ P F+P ++S + +P G ++ + D D G+ + Y
Sbjct: 929 VNDCSPAFIPSSYS-------VKVLEDLPVGTVI--------AWLETHDPDLGLGGQVRY 973
Query: 290 SIFRGNVNGTFIIHPDSGNLTVARSVPSP------MTFLLLVKGQQADLARYSVTQVTVE 343
S+ + NG F I SG + +++ + +T KG+ L+ S +V V
Sbjct: 974 SLV-NDYNGRFEIDKASGAIRLSKELDYEKQQFYNLTVRAKDKGRPVSLSSVSFVEVEVV 1032
Query: 344 AVAAAGSPPRFPQRLYRGTVARGAGAGVVVKDAAAPSQPLRIQAQDPEFSDLNSAITYRI 403
V P FP G+V + G V L++ A+D E S + I Y I
Sbjct: 1033 DVNENLHTPYFPDFAVVGSVKENSRIGTSV---------LQVTARD-EDSGRDGEIQYSI 1082
Query: 404 TNHS---HFRMEGEV-VLTTTTLAQ---AGAFYAEVEAHNTVTSGTATTV---IEIQVSE 453
+ S F ++ E V+T + G+++ V A + +T+ IE++
Sbjct: 1083 RDGSGLGRFSIDDESGVITAADILDRETMGSYWLTVYATDRGVVPLYSTIEVYIEVEDVN 1142
Query: 454 QEPPSTDVP 462
P T P
Sbjct: 1143 DNAPLTSEP 1151
Score = 39.3 bits (90), Expect = 0.015
Identities = 74/304 (24%), Positives = 116/304 (38%), Gaps = 40/304 (13%)
Query: 103 TLVTQLRVFVSVLDVNDNAPEFPFKTKEIRVEEDTKVNSTVIPETQLQAEDRDKDDILFY 162
+L +++ V + + DVNDN P F E V E V T +QA D D D F
Sbjct: 2373 SLSSEVLVHIYISDVNDNPPVFNQLIYESYVSELAPRGHFV---TCVQASDADSSD--FD 2427
Query: 163 TLQEMTAGASDYFSLVSVNRPALRLDRPLDFYERPNMTFWLLVRDTPGENVEPSHTATAT 222
L+ +D S + ++ + + +R + L V + G T+TA
Sbjct: 2428 RLEYSILSGNDRTSFLMDSKSGV-ITLSNHRKQRMEPLYSLNVSVSDG-----LFTSTAQ 2481
Query: 223 LVLNVVPADLRPPWFLPCTFSDGYVCIQAQYHGAVPTGHILPSPLVLRPGPIYAEDGDRG 282
+ + V+ A+L P F T+ A+ V G + + A DGD G
Sbjct: 2482 VHIRVLGANLYSPAFSQSTYV-------AEVRENVAAG--------TKVIHVRATDGDPG 2526
Query: 283 INQPIIYSIFRGNVNGTFIIHPDSGNLT---VARSVPSPMTFLLLVKGQQADLARYSVTQ 339
I Y+I F+I + +T + R P + V+ R +
Sbjct: 2527 TYGQISYAIINDFAKDRFLIDSNGQVITTERLDRENPLEGDVSIFVRALDGG-GRTTFCT 2585
Query: 340 VTVEAVAAAGSPPRFPQRLYRGTVARGAGAGVVVKDAAAPSQPLRIQAQDPEFSDLNSAI 399
V V V + P+F YR +V G G +V ++QA DP+ NS I
Sbjct: 2586 VRVIVVDENDNAPQFMTVEYRASVRADVGRGHLV---------TQVQAIDPD-DGANSRI 2635
Query: 400 TYRI 403
TY +
Sbjct: 2636 TYSL 2639
Score = 37.0 bits (84), Expect = 0.077
Identities = 91/441 (20%), Positives = 167/441 (37%), Gaps = 58/441 (13%)
Query: 40 EENTNVTEPLVDIHVPE--GQEVTLGALSTPFAFRIQGNQLFLNVTP---DYEEKSLLEA 94
E NTN+T+ + V + + L+ F+I+ + T D EE+ L E
Sbjct: 1993 ENNTNITKVAIVNAVGNRLNEPLKYSILNPGNKFKIKSTSGVIQTTGVPFDREEQELYE- 2051
Query: 95 QLLCQSGGTL----VTQLRVFVSVLDVNDNAPEFPFKTKEIRVEEDTKVNSTVIPETQLQ 150
L+ ++ L V ++ V V++ D+NDN+P F V+ D + + + T +
Sbjct: 2052 -LVVEASRELDHLRVARVVVRVNIEDINDNSPVFVGLPYYAAVQVDAEPGTLIYQVTAID 2110
Query: 151 AEDRDKDDILFYTLQEMTAGASDYFSL-VSVNRPALRLDRPLDFYERPNMTF--WLLVRD 207
+D+ + + Y LQ+ DY ++ N + L + + N+ + +L +D
Sbjct: 2111 -KDKGPNGEVTYVLQD------DYGHFEINPNSGNVILKEAFN-SDLSNIEYGVTILAKD 2162
Query: 208 TPGENVEPSHTATATLVLNVVPADLRPPWFLPCTFSDGYVCIQAQYHGAVPTGHILPSPL 267
++ S T+V +P P++ D
Sbjct: 2163 GGKPSLSTSVELPITIVNKAMPV-FDKPFYTASVNED----------------------- 2198
Query: 268 VLRPGPIYAEDGDRGINQPIIYSIFRGNVNGTFIIHPDSGNLTVARSVPSPMTFLLLVKG 327
+ PI + + Q IIY I G+ F I D+G L V + +T +
Sbjct: 2199 IRMNTPILSINATSPEGQGIIYIIIDGDPFKQFNIDFDTGVLKVVSPLDYEVTSAYKLTI 2258
Query: 328 QQADLARYSVTQVTVEAVA--AAGSPPRFPQRLYRGTVARGAGAGVVVKDAAAPSQPLRI 385
+ +D + +VTV+ + +PP F Q Y T++ + G V Q + I
Sbjct: 2259 RASDALTGARAEVTVDLLVNDVNDNPPIFDQPTYNTTLSEASLIGTPV------LQVVSI 2312
Query: 386 QAQDPEFSDLNSAI---TYRITNHSHFRMEGEVVLTTTTLAQAGAFYAEVEAHNTVTSGT 442
A ++ I TY T++ H ++LT L + ++ ++ SG
Sbjct: 2313 DADSENNKMVHYQIVQDTYNSTDYFHIDSSSGLILTARMLDHELVQHCTLKV-RSIDSGF 2371
Query: 443 ATTVIEIQVSEQEPPSTDVPP 463
+ E+ V D PP
Sbjct: 2372 PSLSSEVLVHIYISDVNDNPP 2392
Score = 36.2 bits (82), Expect = 0.13
Identities = 44/207 (21%), Positives = 81/207 (39%), Gaps = 24/207 (11%)
Query: 109 RVFVSVLDVNDNAPEFPFKTKEIRVEEDTKVNSTVIPETQLQAEDRDKDDILFYTLQEMT 168
+V +S+ D ND+ PEF + V E V ++V+ + A D+DK + + T +
Sbjct: 457 QVTISIEDANDHTPEFQQPLYDAYVNESVPVGTSVL---TVSASDKDKGENGYITYSIAS 513
Query: 169 AGASDYFSLVSVNRPALRLDRPLDFYERPNMTFWLLVRDTPGENVEPSHTATATLVLNVV 228
+ +++ + LDF P + +++ G H + + + +
Sbjct: 514 LNLLPF--VINQFTGVISTTEELDFESSPEIYRFIVRASDWGSPYR--HESEVNVTIRIG 569
Query: 229 PADLRPPWFLPCTFSDGYVCIQAQYHGAVPTGHILPSPLVLRPGPIYAEDGDRGINQPII 288
+ P F + C + GHI + A D D + +
Sbjct: 570 NVNDNSPLF------EKVACQGVISYDFPVGGHIT---------AVSAIDIDE--LELVK 612
Query: 289 YSIFRGNVNGTFIIHPDSGNLTVARSV 315
Y I GN G F ++PDSG L + +S+
Sbjct: 613 YKIISGNELGFFYLNPDSGVLQLKKSL 639
Score = 34.7 bits (78), Expect = 0.38
Identities = 64/288 (22%), Positives = 101/288 (35%), Gaps = 38/288 (13%)
Query: 36 IFEVEENTNVTEPLVDIHVPEGQEVTLGALS----TPFA---FRIQGNQLFLNVTPDYEE 88
+ EV EN ++ + +G T G +S FA F I N + T +
Sbjct: 2502 VAEVRENVAAGTKVIHVRATDGDPGTYGQISYAIINDFAKDRFLIDSNGQVIT-TERLDR 2560
Query: 89 KSLLEAQLL----CQSGGTLVTQLRVFVSVLDVNDNAPEFPFKTKEIRVEEDTKVNSTVI 144
++ LE + GG T V V V+D NDNAP+F V D V
Sbjct: 2561 ENPLEGDVSIFVRALDGGGRTTFCTVRVIVVDENDNAPQFMTVEYRASVRADVGRGHLVT 2620
Query: 145 PETQLQAEDRDKDDILFYTLQEMTAGASDYFSLVSVNRPALRLDRPLDFYERPNMTFWLL 204
+ +D I + E + +D L+ ++ + +F + N
Sbjct: 2621 QVQAIDPDDGANSRITYSLYSEASVSVAD---LLEIDPDNGWMVTKGNFNQLKNTVLSFF 2677
Query: 205 VRDTPGENVEPSHTATATLVLNVVPADLRPPWFLPCTFSDGY---VCIQAQYHGAVPTGH 261
V+ G P + + ++V+P P FLP Y + V T
Sbjct: 2678 VKAVDGG--IPVKHSLIPVYIHVLP----PETFLPSFTQSQYSFTIAEDTAIGSTVDTLR 2731
Query: 262 ILPSPLVLRPGPIYAEDGDRGINQPIIYSIFRGNVNGTFIIHPDSGNL 309
ILPS V +G+R N N G F+I ++G +
Sbjct: 2732 ILPSQNVW----FSTVNGERPEN----------NKGGIFVIEQETGTI 2765
Score = 33.9 bits (76), Expect = 0.65
Identities = 74/368 (20%), Positives = 140/368 (38%), Gaps = 53/368 (14%)
Query: 96 LLCQSGGTLVTQLRVFVSVLDVNDNAPEF--PFKTKEIRVEEDTKVNSTVIPETQLQAED 153
+L + GG V + + VN P F PF T V ED ++N+ ++ + A
Sbjct: 2158 ILAKDGGKPSLSTSVELPITIVNKAMPVFDKPFYTAS--VNEDIRMNTPIL---SINATS 2212
Query: 154 RDKDDILFYTLQEMTAGASDYFSLVSV--NRPALRLDRPLDFYERPNMTFWLLVRDTPGE 211
+ I++ + D F ++ + L++ PLD+ + L +R
Sbjct: 2213 PEGQGIIYIIID------GDPFKQFNIDFDTGVLKVVSPLDY--EVTSAYKLTIR---AS 2261
Query: 212 NVEPSHTATATLVLNVVPADLRPPWFLPCTFSDGYVCIQAQYHGAVPTGHILPSPLVLRP 271
+ A T+ L V + PP F Q Y+ + ++ +P++
Sbjct: 2262 DALTGARAEVTVDLLVNDVNDNPPIF-----------DQPTYNTTLSEASLIGTPVL--- 2307
Query: 272 GPIYAEDGDRGINQPIIYSIFRGNVNGTFIIHPD--SGNLTVARSVPSPMTFLLLVKGQQ 329
+ + D D N+ + Y I + N T H D SG + AR + + +K +
Sbjct: 2308 -QVVSIDADSENNKMVHYQIVQDTYNSTDYFHIDSSSGLILTARMLDHELVQHCTLKVRS 2366
Query: 330 ADLARYSVTQ---VTVEAVAAAGSPPRFPQRLYRGTVARGAGAGVVVKDAAAPSQPLRIQ 386
D S++ V + +PP F Q +Y V+ A G V +Q
Sbjct: 2367 IDSGFPSLSSEVLVHIYISDVNDNPPVFNQLIYESYVSELAPRGHFV---------TCVQ 2417
Query: 387 AQDPEFSDLNSAITYRI---TNHSHFRMEGEVVLTTTTLAQAGAFYAEVEAHNTVTSGTA 443
A D + SD + + Y I + + F M+ + + T + + + +V+ G
Sbjct: 2418 ASDADSSDFD-RLEYSILSGNDRTSFLMDSKSGVITLSNHRKQRMEPLYSLNVSVSDGLF 2476
Query: 444 TTVIEIQV 451
T+ ++ +
Sbjct: 2477 TSTAQVHI 2484
Score = 33.1 bits (74), Expect = 1.1
Identities = 77/378 (20%), Positives = 136/378 (35%), Gaps = 53/378 (14%)
Query: 101 GGTLVTQLRVFVSVLDVNDNAPEFPFKTKEIRVEEDTKVNSTVIPETQLQAEDRDKDDIL 160
G L +V + VLD+ND P F T + + E T + ++V T A+ +
Sbjct: 135 GEDLEAWTKVNIQVLDMNDLRPLFSPTTYSVTIAESTPLRTSVAQVTATDADIGSNGEFY 194
Query: 161 FYTLQEMTAGASDYFSLVSVNRPALRLDRPLDFYERPNMTFWLLVRDTPGENVEPSHTAT 220
+Y ++ D FS V + L L++ E+ +L D G + ++ +
Sbjct: 195 YYFKNKV-----DLFS-VHPTSGVISLSGRLNYDEKNRYDLEILAVDR-GMKLYGNNGVS 247
Query: 221 ATLVLNVVPADLRPPWFLPCTFSDGYVCIQAQYHGAVPTGHILPS-PLVLRPGPIYA--- 276
+T L YV I+ + + PT H++ P L P YA
Sbjct: 248 STAKL--------------------YVHIE-RINEHAPTIHVVTHVPFSLEKEPTYAVVT 286
Query: 277 -EDGDRGINQPI-IYSIFRGNVNGTFIIHPDSGNLTVAR----------SVPSPMTFLLL 324
+D D G N I SI G+ F + + L + S P L
Sbjct: 287 VDDLDDGANGEIESVSIVAGDPLDQFFLAKEGKWLNEYKIKERKQIDWESFPYGYNLTLQ 346
Query: 325 VKGQQADLARYSVTQVTVEAVAAAGSPPRFPQRLYRGTVARGAGAGVVVKDAAAPSQPLR 384
K + + ++ V + P RF + +Y +++ + GVVV +P+
Sbjct: 347 AKDKGSPQKCSALKAVYIGNPTRDTVPIRFEKEVYDVSISEFSPPGVVVAIVKLSPEPID 406
Query: 385 IQAQDPEFSDLNSAITYRITNHSHFRMEGEVVLTTTTLAQAGAFYAEVEAHNTVTSGTAT 444
++ + S A+ ++I S +++T L ++E N A
Sbjct: 407 VEY---KLSPGEDAVYFKINPRS------GLIVTARPLNTVKKEVYKLEVTNKEGDLKAQ 457
Query: 445 TVIEIQVSEQEPPSTDVP 462
I I+ + P P
Sbjct: 458 VTISIEDANDHTPEFQQP 475
Score = 30.8 bits (68), Expect = 5.5
Identities = 47/214 (21%), Positives = 79/214 (36%), Gaps = 47/214 (21%)
Query: 104 LVTQLRVFVSVLDVNDNAPEFPFKTKEIRVEEDTKVNSTVIPETQLQAEDRDKDDILFYT 163
+V + V + VLD+NDN P F + + + E V + + TQ++A D D
Sbjct: 2794 IVFTVDVDIKVLDLNDNKPVFETSSYDTIIMEGMPVGTKL---TQVRAIDMD-------- 2842
Query: 164 LQEMTAGASDYFSLVSVNRPALRLDRPLDFYERPNMTFWLLVRDTPGENVEPSHTATATL 223
A +SL S ++P ++ ++ + + T W+ + H T
Sbjct: 2843 ---WGANGQVTYSLHSDSQP----EKVMEAFNIDSNTGWISTLK------DLDHETDPTF 2889
Query: 224 VLNVVPADLRPPWFLPCTF----------SDGYVCIQAQYHGAVPTGHILPSPLVLRPGP 273
+VV +DL + L T + V Q Y G V PG
Sbjct: 2890 TFSVVASDLGEAFSLSSTALVSVRVTDINDNAPVFAQEVYRGNVKESD--------PPGE 2941
Query: 274 IYA-----EDGDRGINQPIIYSIFRGNVNGTFII 302
+ A + +N+ + Y I GN G F +
Sbjct: 2942 VVAVLSTWDRDTSDVNRQVSYHITGGNPRGRFAL 2975
Score = 30.0 bits (66), Expect = 9.4
Identities = 33/119 (27%), Positives = 46/119 (38%), Gaps = 16/119 (13%)
Query: 289 YSIFRGNVNGTFIIHPDSGNLTVARSVPSPM--TFLLLVKGQQADLARYSVTQVTVEAVA 346
Y + G F I+P SG + AR + + + L V ++ DL QVT+
Sbjct: 409 YKLSPGEDAVYFKINPRSGLIVTARPLNTVKKEVYKLEVTNKEGDLK----AQVTISIED 464
Query: 347 AAGSPPRFPQRLYRGTVARGAGAGVVVKDAAAPSQPLRIQAQDPEFSDLNSAITYRITN 405
A P F Q LY V G V L + A D + + N ITY I +
Sbjct: 465 ANDHTPEFQQPLYDAYVNESVPVGTSV---------LTVSASDKDKGE-NGYITYSIAS 513
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 73.6 bits (179), Expect = 7e-13
Identities = 70/242 (28%), Positives = 86/242 (35%), Gaps = 35/242 (14%)
Query: 410 RMEGEVVLTTTTLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPSTDVPPSPEAGG 469
++ GEV T L A A + A I V P VPP+P G
Sbjct: 534 QLTGEVAKLTKELEDAKKEMASLSA------------AAITVPPSVPSRAPVPPAPPLPG 581
Query: 470 TTG--------PWTSTTSEVPRPPEPSQGPSTTSSGGGTGPHPPSGTTLRPPT-----SS 516
+G P STT P PP P P + P P GT + PP ++
Sbjct: 582 DSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDAT 641
Query: 517 TPGGPPGAENSTSHQPATPGGDTA---QTPKPGTSQ---PMPPGVGTSTSHQPATPSGGT 570
P PP E P++ G TA P PG+++ P PP G++ P P G
Sbjct: 642 IPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGE 701
Query: 571 AQTPEPGTSQPMPPSMGTSTSHQPATPGGGTAQTPEAGTSQPMPPGMGTSTSHQPTTPGG 630
A P P P P G P PGG P G P PP G P P G
Sbjct: 702 AGMPPP----PPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLPFG 757
Query: 631 GT 632
T
Sbjct: 758 LT 759
Score = 55.1 bits (131), Expect = 3e-07
Identities = 50/180 (27%), Positives = 59/180 (32%), Gaps = 40/180 (22%)
Query: 504 PPSGTTLRPPTSSTPGGPPGAENSTSHQPATPGGDTAQTPKPGTSQPMPPGVGTSTSHQP 563
PPS + P + P PG + P PG T P P P PP G P
Sbjct: 564 PPSVPSRAPVPPAPP--LPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSP 621
Query: 564 ATPSGGTAQTPEP----------------GTSQPMPPSMGTSTSHQPATPGGGTAQTP-- 605
+ GGTA +P P G P P S+ T+ P P G+A+ P
Sbjct: 622 PSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPP 681
Query: 606 -------------------EAGTSQPMPP-GMGTSTSHQPTTPGGGTAQTPEPGTSQPMP 645
EAG P PP G P PGG P PG P P
Sbjct: 682 PPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPP 741
Score = 51.6 bits (122), Expect = 3e-06
Identities = 63/243 (25%), Positives = 77/243 (31%), Gaps = 65/243 (26%)
Query: 521 PPGAENSTSHQPATP-GGDTAQTPKPGTSQPMPPGVGTSTSHQPATPSGGTAQTPEPGTS 579
PP + PA P GD+ GT P PP G ST+ P P G
Sbjct: 564 PPSVPSRAPVPPAPPLPGDS------GTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVC 617
Query: 580 QPMPPSMGTSTSHQPATPGGGTAQTPEAGTSQPMPPGMGTSTSHQPTTPGGGTAQTPEPG 639
PPS+ T+ P P G A P P+P G+G + P++ GGTA P P
Sbjct: 618 ISSPPSLPGGTAISPPPPLSGDATIPPP---PPLPEGVGIPS---PSSLPGGTAIPPPP- 670
Query: 640 TSQPMPLSKSTPSSGGGPSEDKRFSVVDMAALGGVLGALLLLALLGLAVLVHKHYGPRLK 699
P+P S P P L
Sbjct: 671 ---PLPGSARIPPPP-----------------------------------------PPLP 686
Query: 700 CCSGKAPEPQPQGFDNQAFLPDHKANWAPVPSPTHDPKPAEAPMPAEPAPPGPASPGGAP 759
+G P P P +A +P P P P P P P P P P G P
Sbjct: 687 GSAGIPPPPPP--LPGEAGMPP-----PPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMP 739
Query: 760 EPP 762
PP
Sbjct: 740 PPP 742
Score = 49.7 bits (117), Expect = 1e-05
Identities = 66/225 (29%), Positives = 79/225 (35%), Gaps = 60/225 (26%)
Query: 551 MPPGVGTSTSHQPATPSGGTAQTPEPGTSQPMPPSMGTSTSHQPATPGGGTAQTPEAGTS 610
+PP V + PA P G + GT P PP+ G ST+ P P
Sbjct: 563 VPPSVPSRAPVPPAPPLPG-----DSGTIIPPPPAPGDSTTPPPPPP------------P 605
Query: 611 QPMPPGM--GTSTSHQPTTPGGGTAQTPEPGTS--QPMPLSKSTPSSGGGPSEDKRFSVV 666
P PP + G S P+ PGG TA +P P S +P P G PS
Sbjct: 606 PPPPPPLPGGVCISSPPSLPGG-TAISPPPPLSGDATIPPPPPLPEGVGIPSP------- 657
Query: 667 DMAALGGVLGALLLLALLGLAVLVHKHYGPRLKCCSGKAPEPQPQGFDNQAFLPDHKANW 726
++L G G A+ P G A P P P
Sbjct: 658 --SSLPG-----------GTAI-------PPPPPLPGSARIPPP---------PPPLPGS 688
Query: 727 APVPSPTHDPKPAEAPMPAEPAPPGPASPGGAPEPPAAARAGGSP 771
A +P P P P EA MP P PP P PG P PP G P
Sbjct: 689 AGIPPPP-PPLPGEAGMP-PPPPPLPGGPGIPPPPPFPGGPGIPP 731
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 73.6 bits (179), Expect = 7e-13
Identities = 70/242 (28%), Positives = 86/242 (35%), Gaps = 35/242 (14%)
Query: 410 RMEGEVVLTTTTLAQAGAFYAEVEAHNTVTSGTATTVIEIQVSEQEPPSTDVPPSPEAGG 469
++ GEV T L A A + A I V P VPP+P G
Sbjct: 543 QLTGEVAKLTKELEDAKKEMASLSA------------AAITVPPSVPSRAPVPPAPPLPG 590
Query: 470 TTG--------PWTSTTSEVPRPPEPSQGPSTTSSGGGTGPHPPSGTTLRPPT-----SS 516
+G P STT P PP P P + P P GT + PP ++
Sbjct: 591 DSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDAT 650
Query: 517 TPGGPPGAENSTSHQPATPGGDTA---QTPKPGTSQ---PMPPGVGTSTSHQPATPSGGT 570
P PP E P++ G TA P PG+++ P PP G++ P P G
Sbjct: 651 IPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGE 710
Query: 571 AQTPEPGTSQPMPPSMGTSTSHQPATPGGGTAQTPEAGTSQPMPPGMGTSTSHQPTTPGG 630
A P P P P G P PGG P G P PP G P P G
Sbjct: 711 AGMPPP----PPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLPFG 766
Query: 631 GT 632
T
Sbjct: 767 LT 768
Score = 55.1 bits (131), Expect = 3e-07
Identities = 50/180 (27%), Positives = 59/180 (32%), Gaps = 40/180 (22%)
Query: 504 PPSGTTLRPPTSSTPGGPPGAENSTSHQPATPGGDTAQTPKPGTSQPMPPGVGTSTSHQP 563
PPS + P + P PG + P PG T P P P PP G P
Sbjct: 573 PPSVPSRAPVPPAPP--LPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSP 630
Query: 564 ATPSGGTAQTPEP----------------GTSQPMPPSMGTSTSHQPATPGGGTAQTP-- 605
+ GGTA +P P G P P S+ T+ P P G+A+ P
Sbjct: 631 PSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPP 690
Query: 606 -------------------EAGTSQPMPP-GMGTSTSHQPTTPGGGTAQTPEPGTSQPMP 645
EAG P PP G P PGG P PG P P
Sbjct: 691 PPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPP 750
Score = 51.6 bits (122), Expect = 3e-06
Identities = 63/243 (25%), Positives = 77/243 (31%), Gaps = 65/243 (26%)
Query: 521 PPGAENSTSHQPATP-GGDTAQTPKPGTSQPMPPGVGTSTSHQPATPSGGTAQTPEPGTS 579
PP + PA P GD+ GT P PP G ST+ P P G
Sbjct: 573 PPSVPSRAPVPPAPPLPGDS------GTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVC 626
Query: 580 QPMPPSMGTSTSHQPATPGGGTAQTPEAGTSQPMPPGMGTSTSHQPTTPGGGTAQTPEPG 639
PPS+ T+ P P G A P P+P G+G + P++ GGTA P P
Sbjct: 627 ISSPPSLPGGTAISPPPPLSGDATIPPP---PPLPEGVGIPS---PSSLPGGTAIPPPP- 679
Query: 640 TSQPMPLSKSTPSSGGGPSEDKRFSVVDMAALGGVLGALLLLALLGLAVLVHKHYGPRLK 699
P+P S P P L
Sbjct: 680 ---PLPGSARIPPPP-----------------------------------------PPLP 695
Query: 700 CCSGKAPEPQPQGFDNQAFLPDHKANWAPVPSPTHDPKPAEAPMPAEPAPPGPASPGGAP 759
+G P P P +A +P P P P P P P P P P G P
Sbjct: 696 GSAGIPPPPPP--LPGEAGMPP-----PPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMP 748
Query: 760 EPP 762
PP
Sbjct: 749 PPP 751
Score = 49.7 bits (117), Expect = 1e-05
Identities = 66/225 (29%), Positives = 79/225 (35%), Gaps = 60/225 (26%)
Query: 551 MPPGVGTSTSHQPATPSGGTAQTPEPGTSQPMPPSMGTSTSHQPATPGGGTAQTPEAGTS 610
+PP V + PA P G + GT P PP+ G ST+ P P
Sbjct: 572 VPPSVPSRAPVPPAPPLPG-----DSGTIIPPPPAPGDSTTPPPPPP------------P 614
Query: 611 QPMPPGM--GTSTSHQPTTPGGGTAQTPEPGTS--QPMPLSKSTPSSGGGPSEDKRFSVV 666
P PP + G S P+ PGG TA +P P S +P P G PS
Sbjct: 615 PPPPPPLPGGVCISSPPSLPGG-TAISPPPPLSGDATIPPPPPLPEGVGIPSP------- 666
Query: 667 DMAALGGVLGALLLLALLGLAVLVHKHYGPRLKCCSGKAPEPQPQGFDNQAFLPDHKANW 726
++L G G A+ P G A P P P
Sbjct: 667 --SSLPG-----------GTAI-------PPPPPLPGSARIPPP---------PPPLPGS 697
Query: 727 APVPSPTHDPKPAEAPMPAEPAPPGPASPGGAPEPPAAARAGGSP 771
A +P P P P EA MP P PP P PG P PP G P
Sbjct: 698 AGIPPPP-PPLPGEAGMP-PPPPPLPGGPGIPPPPPFPGGPGIPP 740
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.132 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,848,604
Number of Sequences: 37866
Number of extensions: 3279452
Number of successful extensions: 56442
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 769
Number of HSP's successfully gapped in prelim test: 2268
Number of HSP's that attempted gapping in prelim test: 19058
Number of HSP's gapped (non-prelim): 21066
length of query: 845
length of database: 18,247,518
effective HSP length: 111
effective length of query: 734
effective length of database: 14,044,392
effective search space: 10308583728
effective search space used: 10308583728
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.