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Search of human proteins with 110618244
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|110618244 retinoblastoma binding protein 2 isoform 1 [Homo
sapiens]
(1690 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|110618244 retinoblastoma binding protein 2 isoform 1 [Homo sa... 3413 0.0
gi|110618242 retinoblastoma binding protein 2 isoform 2 [Homo sa... 3256 0.0
gi|109255243 jumonji, AT rich interactive domain 1C isoform 1 [H... 1498 0.0
gi|57242796 jumonji, AT rich interactive domain 1B [Homo sapiens] 1498 0.0
gi|33356560 jumonji, AT rich interactive domain 1D isoform 2 [Ho... 1463 0.0
gi|226442991 jumonji, AT rich interactive domain 1D isoform 1 [H... 1447 0.0
gi|226443002 jumonji, AT rich interactive domain 1D isoform 3 [H... 1377 0.0
gi|226442963 jumonji, AT rich interactive domain 1C isoform 2 [H... 1311 0.0
gi|169218173 PREDICTED: similar to Jumonji, AT rich interactive ... 1241 0.0
gi|39653317 jumonji domain containing 2D [Homo sapiens] 154 5e-37
gi|239755681 PREDICTED: hypothetical protein [Homo sapiens] 151 5e-36
gi|239750150 PREDICTED: hypothetical protein [Homo sapiens] 151 5e-36
gi|239744460 PREDICTED: hypothetical protein [Homo sapiens] 151 5e-36
gi|169203160 PREDICTED: hypothetical protein [Homo sapiens] 149 3e-35
gi|169203656 PREDICTED: hypothetical protein [Homo sapiens] 149 3e-35
gi|169202387 PREDICTED: hypothetical protein [Homo sapiens] 149 3e-35
gi|11863152 jumonji, AT rich interactive domain 2 protein [Homo ... 147 7e-35
gi|226442893 jumonji domain containing 2C isoform 3 [Homo sapiens] 144 7e-34
gi|98986459 jumonji domain containing 2A [Homo sapiens] 144 7e-34
gi|226442897 jumonji domain containing 2C isoform 4 [Homo sapiens] 144 7e-34
gi|226442889 jumonji domain containing 2C isoform 2 [Homo sapiens] 144 7e-34
gi|109255247 jumonji domain containing 2C isoform 1 [Homo sapiens] 144 7e-34
gi|45504380 jumonji domain containing 2B [Homo sapiens] 140 1e-32
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 72 5e-12
gi|221139764 PHD and ring finger domains 1 [Homo sapiens] 72 6e-12
gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo s... 70 2e-11
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo... 69 3e-11
gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo... 66 3e-10
gi|205830434 D4, zinc and double PHD fingers family 1 isoform c ... 65 6e-10
gi|205830430 D4, zinc and double PHD fingers family 1 isoform a ... 65 6e-10
>gi|110618244 retinoblastoma binding protein 2 isoform 1 [Homo
sapiens]
Length = 1690
Score = 3413 bits (8849), Expect = 0.0
Identities = 1690/1690 (100%), Positives = 1690/1690 (100%)
Query: 1 MAGVGPGGYAAEFVPPPECPVFEPSWEEFTDPLSFIGRIRPLAEKTGICKIRPPKDWQPP 60
MAGVGPGGYAAEFVPPPECPVFEPSWEEFTDPLSFIGRIRPLAEKTGICKIRPPKDWQPP
Sbjct: 1 MAGVGPGGYAAEFVPPPECPVFEPSWEEFTDPLSFIGRIRPLAEKTGICKIRPPKDWQPP 60
Query: 61 FACEVKSFRFTPRVQRLNELEAMTRVRLDFLDQLAKFWELQGSTLKIPVVERKILDLYAL 120
FACEVKSFRFTPRVQRLNELEAMTRVRLDFLDQLAKFWELQGSTLKIPVVERKILDLYAL
Sbjct: 61 FACEVKSFRFTPRVQRLNELEAMTRVRLDFLDQLAKFWELQGSTLKIPVVERKILDLYAL 120
Query: 121 SKIVASKGGFEMVTKEKKWSKVGSRLGYLPGKGTGSLLKSHYERILYPYELFQSGVSLMG 180
SKIVASKGGFEMVTKEKKWSKVGSRLGYLPGKGTGSLLKSHYERILYPYELFQSGVSLMG
Sbjct: 121 SKIVASKGGFEMVTKEKKWSKVGSRLGYLPGKGTGSLLKSHYERILYPYELFQSGVSLMG 180
Query: 181 VQMPNLDLKEKVEPEVLSTDTQTSPEPGTRMNILPKRTRRVKTQSESGDVSRNTELKKLQ 240
VQMPNLDLKEKVEPEVLSTDTQTSPEPGTRMNILPKRTRRVKTQSESGDVSRNTELKKLQ
Sbjct: 181 VQMPNLDLKEKVEPEVLSTDTQTSPEPGTRMNILPKRTRRVKTQSESGDVSRNTELKKLQ 240
Query: 241 IFGAGPKVVGLAMGTKDKEDEVTRRRKVTNRSDAFNMQMRQRKGTLSVNFVDLYVCMFCG 300
IFGAGPKVVGLAMGTKDKEDEVTRRRKVTNRSDAFNMQMRQRKGTLSVNFVDLYVCMFCG
Sbjct: 241 IFGAGPKVVGLAMGTKDKEDEVTRRRKVTNRSDAFNMQMRQRKGTLSVNFVDLYVCMFCG 300
Query: 301 RGNNEDKLLLCDGCDDSYHTFCLIPPLPDVPKGDWRCPKCVAEECSKPREAFGFEQAVRE 360
RGNNEDKLLLCDGCDDSYHTFCLIPPLPDVPKGDWRCPKCVAEECSKPREAFGFEQAVRE
Sbjct: 301 RGNNEDKLLLCDGCDDSYHTFCLIPPLPDVPKGDWRCPKCVAEECSKPREAFGFEQAVRE 360
Query: 361 YTLQSFGEMADNFKSDYFNMPVHMVPTELVEKEFWRLVSSIEEDVIVEYGADISSKDFGS 420
YTLQSFGEMADNFKSDYFNMPVHMVPTELVEKEFWRLVSSIEEDVIVEYGADISSKDFGS
Sbjct: 361 YTLQSFGEMADNFKSDYFNMPVHMVPTELVEKEFWRLVSSIEEDVIVEYGADISSKDFGS 420
Query: 421 GFPVKDGRRKILPEEEEYALSGWNLNNMPVLEQSVLAHINVDISGMKVPWLYVGMCFSSF 480
GFPVKDGRRKILPEEEEYALSGWNLNNMPVLEQSVLAHINVDISGMKVPWLYVGMCFSSF
Sbjct: 421 GFPVKDGRRKILPEEEEYALSGWNLNNMPVLEQSVLAHINVDISGMKVPWLYVGMCFSSF 480
Query: 481 CWHIEDHWSYSINYLHWGEPKTWYGVPSHAAEQLEEVMRELAPELFESQPDLLHQLVTIM 540
CWHIEDHWSYSINYLHWGEPKTWYGVPSHAAEQLEEVMRELAPELFESQPDLLHQLVTIM
Sbjct: 481 CWHIEDHWSYSINYLHWGEPKTWYGVPSHAAEQLEEVMRELAPELFESQPDLLHQLVTIM 540
Query: 541 NPNVLMEHGVPVYRTNQCAGEFVVTFPRAYHSGFNQGYNFAEAVNFCTADWLPIGRQCVN 600
NPNVLMEHGVPVYRTNQCAGEFVVTFPRAYHSGFNQGYNFAEAVNFCTADWLPIGRQCVN
Sbjct: 541 NPNVLMEHGVPVYRTNQCAGEFVVTFPRAYHSGFNQGYNFAEAVNFCTADWLPIGRQCVN 600
Query: 601 HYRRLRRHCVFSHEELIFKMAADPECLDVGLAAMVCKELTLMTEEETRLRESVVQMGVLM 660
HYRRLRRHCVFSHEELIFKMAADPECLDVGLAAMVCKELTLMTEEETRLRESVVQMGVLM
Sbjct: 601 HYRRLRRHCVFSHEELIFKMAADPECLDVGLAAMVCKELTLMTEEETRLRESVVQMGVLM 660
Query: 661 SEEEVFELVPDDERQCSACRTTCFLSALTCSCNPERLVCLYHPTDLCPCPMQKKCLRYRY 720
SEEEVFELVPDDERQCSACRTTCFLSALTCSCNPERLVCLYHPTDLCPCPMQKKCLRYRY
Sbjct: 661 SEEEVFELVPDDERQCSACRTTCFLSALTCSCNPERLVCLYHPTDLCPCPMQKKCLRYRY 720
Query: 721 PLEDLPSLLYGVKVRAQSYDTWVSRVTEALSANFNHKKDLIELRVMLEDAEDRKYPENDL 780
PLEDLPSLLYGVKVRAQSYDTWVSRVTEALSANFNHKKDLIELRVMLEDAEDRKYPENDL
Sbjct: 721 PLEDLPSLLYGVKVRAQSYDTWVSRVTEALSANFNHKKDLIELRVMLEDAEDRKYPENDL 780
Query: 781 FRKLRDAVKEAETCASVAQLLLSKKQKHRQSPDSGRTRTKLTVEELKAFVQQLFSLPCVI 840
FRKLRDAVKEAETCASVAQLLLSKKQKHRQSPDSGRTRTKLTVEELKAFVQQLFSLPCVI
Sbjct: 781 FRKLRDAVKEAETCASVAQLLLSKKQKHRQSPDSGRTRTKLTVEELKAFVQQLFSLPCVI 840
Query: 841 SQARQVKNLLDDVEEFHERAQEAMMDETPDSSKLQMLIDMGSSLYVELPELPRLKQELQQ 900
SQARQVKNLLDDVEEFHERAQEAMMDETPDSSKLQMLIDMGSSLYVELPELPRLKQELQQ
Sbjct: 841 SQARQVKNLLDDVEEFHERAQEAMMDETPDSSKLQMLIDMGSSLYVELPELPRLKQELQQ 900
Query: 901 ARWLDEVRLTLSDPQQVTLDVMKKLIDSGVGLAPHHAVEKAMAELQELLTVSERWEEKAK 960
ARWLDEVRLTLSDPQQVTLDVMKKLIDSGVGLAPHHAVEKAMAELQELLTVSERWEEKAK
Sbjct: 901 ARWLDEVRLTLSDPQQVTLDVMKKLIDSGVGLAPHHAVEKAMAELQELLTVSERWEEKAK 960
Query: 961 VCLQARPRHSVASLESIVNEAKNIPAFLPNVLSLKEALQKAREWTAKVEAIQSGSNYAYL 1020
VCLQARPRHSVASLESIVNEAKNIPAFLPNVLSLKEALQKAREWTAKVEAIQSGSNYAYL
Sbjct: 961 VCLQARPRHSVASLESIVNEAKNIPAFLPNVLSLKEALQKAREWTAKVEAIQSGSNYAYL 1020
Query: 1021 EQLESLSAKGRPIPVRLEALPQVESQVAAARAWRERTGRTFLKKNSSHTLLQVLSPRTDI 1080
EQLESLSAKGRPIPVRLEALPQVESQVAAARAWRERTGRTFLKKNSSHTLLQVLSPRTDI
Sbjct: 1021 EQLESLSAKGRPIPVRLEALPQVESQVAAARAWRERTGRTFLKKNSSHTLLQVLSPRTDI 1080
Query: 1081 GVYGSGKNRRKKVKELIEKEKEKDLDLEPLSDLEEGLEETRDTAMVVAVFKEREQKEIEA 1140
GVYGSGKNRRKKVKELIEKEKEKDLDLEPLSDLEEGLEETRDTAMVVAVFKEREQKEIEA
Sbjct: 1081 GVYGSGKNRRKKVKELIEKEKEKDLDLEPLSDLEEGLEETRDTAMVVAVFKEREQKEIEA 1140
Query: 1141 MHSLRAANLAKMTMVDRIEEVKFCICRKTASGFMLQCELCKDWFHNSCVPLPKSSSQKKG 1200
MHSLRAANLAKMTMVDRIEEVKFCICRKTASGFMLQCELCKDWFHNSCVPLPKSSSQKKG
Sbjct: 1141 MHSLRAANLAKMTMVDRIEEVKFCICRKTASGFMLQCELCKDWFHNSCVPLPKSSSQKKG 1200
Query: 1201 SSWQAKEVKFLCPLCMRSRRPRLETILSLLVSLQKLPVRLPEGEALQCLTERAMSWQDRA 1260
SSWQAKEVKFLCPLCMRSRRPRLETILSLLVSLQKLPVRLPEGEALQCLTERAMSWQDRA
Sbjct: 1201 SSWQAKEVKFLCPLCMRSRRPRLETILSLLVSLQKLPVRLPEGEALQCLTERAMSWQDRA 1260
Query: 1261 RQALATDELSSALAKLSVLSQRMVEQAAREKTEKIISAELQKAAANPDLQGHLPSFQQSA 1320
RQALATDELSSALAKLSVLSQRMVEQAAREKTEKIISAELQKAAANPDLQGHLPSFQQSA
Sbjct: 1261 RQALATDELSSALAKLSVLSQRMVEQAAREKTEKIISAELQKAAANPDLQGHLPSFQQSA 1320
Query: 1321 FNRVVSSVSSSPRQTMDYDDEETDSDEDIRETYGYDMKDTASVKSSSSLEPNLFCDEEIP 1380
FNRVVSSVSSSPRQTMDYDDEETDSDEDIRETYGYDMKDTASVKSSSSLEPNLFCDEEIP
Sbjct: 1321 FNRVVSSVSSSPRQTMDYDDEETDSDEDIRETYGYDMKDTASVKSSSSLEPNLFCDEEIP 1380
Query: 1381 IKSEEVVTHMWTAPSFCAEHAYSSASKSCSQGSSTPRKQPRKSPLVPRSLEPPVLELSPG 1440
IKSEEVVTHMWTAPSFCAEHAYSSASKSCSQGSSTPRKQPRKSPLVPRSLEPPVLELSPG
Sbjct: 1381 IKSEEVVTHMWTAPSFCAEHAYSSASKSCSQGSSTPRKQPRKSPLVPRSLEPPVLELSPG 1440
Query: 1441 AKAQLEELMMVGDLLEVSLDETQHIWRILQATHPPSEDRFLHIMEDDSMEEKPLKVKGKD 1500
AKAQLEELMMVGDLLEVSLDETQHIWRILQATHPPSEDRFLHIMEDDSMEEKPLKVKGKD
Sbjct: 1441 AKAQLEELMMVGDLLEVSLDETQHIWRILQATHPPSEDRFLHIMEDDSMEEKPLKVKGKD 1500
Query: 1501 SSEKKRKRKLEKVEQLFGEGKQKSKELKKMDKPRKKKLKLGADKSKELNKLAKKLAKEEE 1560
SSEKKRKRKLEKVEQLFGEGKQKSKELKKMDKPRKKKLKLGADKSKELNKLAKKLAKEEE
Sbjct: 1501 SSEKKRKRKLEKVEQLFGEGKQKSKELKKMDKPRKKKLKLGADKSKELNKLAKKLAKEEE 1560
Query: 1561 RKKKKEKAAAAKVELVKESTEKKREKKVLDIPSKYDWSGAEESDDENAVCAAQNCQRPCK 1620
RKKKKEKAAAAKVELVKESTEKKREKKVLDIPSKYDWSGAEESDDENAVCAAQNCQRPCK
Sbjct: 1561 RKKKKEKAAAAKVELVKESTEKKREKKVLDIPSKYDWSGAEESDDENAVCAAQNCQRPCK 1620
Query: 1621 DKVDWVQCDGGCDEWFHQVCVGVSPEMAENEDYICINCAKKQGPVSPGPAPPPSFIMSYK 1680
DKVDWVQCDGGCDEWFHQVCVGVSPEMAENEDYICINCAKKQGPVSPGPAPPPSFIMSYK
Sbjct: 1621 DKVDWVQCDGGCDEWFHQVCVGVSPEMAENEDYICINCAKKQGPVSPGPAPPPSFIMSYK 1680
Query: 1681 LPMEDLKETS 1690
LPMEDLKETS
Sbjct: 1681 LPMEDLKETS 1690
>gi|110618242 retinoblastoma binding protein 2 isoform 2 [Homo
sapiens]
Length = 1641
Score = 3256 bits (8443), Expect = 0.0
Identities = 1622/1627 (99%), Positives = 1622/1627 (99%), Gaps = 5/1627 (0%)
Query: 1 MAGVGPGGYAAEFVPPPECPVFEPSWEEFTDPLSFIGRIRPLAEKTGICKIRPPKDWQPP 60
MAGVGPGGYAAEFVPPPECPVFEPSWEEFTDPLSFIGRIRPLAEKTGICKIRPPKDWQPP
Sbjct: 1 MAGVGPGGYAAEFVPPPECPVFEPSWEEFTDPLSFIGRIRPLAEKTGICKIRPPKDWQPP 60
Query: 61 FACEVKSFRFTPRVQRLNELEAMTRVRLDFLDQLAKFWELQGSTLKIPVVERKILDLYAL 120
FACEVKSFRFTPRVQRLNELEAMTRVRLDFLDQLAKFWELQGSTLKIPVVERKILDLYAL
Sbjct: 61 FACEVKSFRFTPRVQRLNELEAMTRVRLDFLDQLAKFWELQGSTLKIPVVERKILDLYAL 120
Query: 121 SKIVASKGGFEMVTKEKKWSKVGSRLGYLPGKGTGSLLKSHYERILYPYELFQSGVSLMG 180
SKIVASKGGFEMVTKEKKWSKVGSRLGYLPGKGTGSLLKSHYERILYPYELFQSGVSLMG
Sbjct: 121 SKIVASKGGFEMVTKEKKWSKVGSRLGYLPGKGTGSLLKSHYERILYPYELFQSGVSLMG 180
Query: 181 VQMPNLDLKEKVEPEVLSTDTQTSPEPGTRMNILPKRTRRVKTQSESGDVSRNTELKKLQ 240
VQMPNLDLKEKVEPEVLSTDTQTSPEPGTRMNILPKRTRRVKTQSESGDVSRNTELKKLQ
Sbjct: 181 VQMPNLDLKEKVEPEVLSTDTQTSPEPGTRMNILPKRTRRVKTQSESGDVSRNTELKKLQ 240
Query: 241 IFGAGPKVVGLAMGTKDKEDEVTRRRKVTNRSDAFNMQMRQRKGTLSVNFVDLYVCMFCG 300
IFGAGPKVVGLAMGTKDKEDEVTRRRKVTNRSDAFNMQMRQRKGTLSVNFVDLYVCMFCG
Sbjct: 241 IFGAGPKVVGLAMGTKDKEDEVTRRRKVTNRSDAFNMQMRQRKGTLSVNFVDLYVCMFCG 300
Query: 301 RGNNEDKLLLCDGCDDSYHTFCLIPPLPDVPKGDWRCPKCVAEECSKPREAFGFEQAVRE 360
RGNNEDKLLLCDGCDDSYHTFCLIPPLPDVPKGDWRCPKCVAEECSKPREAFGFEQAVRE
Sbjct: 301 RGNNEDKLLLCDGCDDSYHTFCLIPPLPDVPKGDWRCPKCVAEECSKPREAFGFEQAVRE 360
Query: 361 YTLQSFGEMADNFKSDYFNMPVHMVPTELVEKEFWRLVSSIEEDVIVEYGADISSKDFGS 420
YTLQSFGEMADNFKSDYFNMPVHMVPTELVEKEFWRLVSSIEEDVIVEYGADISSKDFGS
Sbjct: 361 YTLQSFGEMADNFKSDYFNMPVHMVPTELVEKEFWRLVSSIEEDVIVEYGADISSKDFGS 420
Query: 421 GFPVKDGRRKILPEEEEYALSGWNLNNMPVLEQSVLAHINVDISGMKVPWLYVGMCFSSF 480
GFPVKDGRRKILPEEEEYALSGWNLNNMPVLEQSVLAHINVDISGMKVPWLYVGMCFSSF
Sbjct: 421 GFPVKDGRRKILPEEEEYALSGWNLNNMPVLEQSVLAHINVDISGMKVPWLYVGMCFSSF 480
Query: 481 CWHIEDHWSYSINYLHWGEPKTWYGVPSHAAEQLEEVMRELAPELFESQPDLLHQLVTIM 540
CWHIEDHWSYSINYLHWGEPKTWYGVPSHAAEQLEEVMRELAPELFESQPDLLHQLVTIM
Sbjct: 481 CWHIEDHWSYSINYLHWGEPKTWYGVPSHAAEQLEEVMRELAPELFESQPDLLHQLVTIM 540
Query: 541 NPNVLMEHGVPVYRTNQCAGEFVVTFPRAYHSGFNQGYNFAEAVNFCTADWLPIGRQCVN 600
NPNVLMEHGVPVYRTNQCAGEFVVTFPRAYHSGFNQGYNFAEAVNFCTADWLPIGRQCVN
Sbjct: 541 NPNVLMEHGVPVYRTNQCAGEFVVTFPRAYHSGFNQGYNFAEAVNFCTADWLPIGRQCVN 600
Query: 601 HYRRLRRHCVFSHEELIFKMAADPECLDVGLAAMVCKELTLMTEEETRLRESVVQMGVLM 660
HYRRLRRHCVFSHEELIFKMAADPECLDVGLAAMVCKELTLMTEEETRLRESVVQMGVLM
Sbjct: 601 HYRRLRRHCVFSHEELIFKMAADPECLDVGLAAMVCKELTLMTEEETRLRESVVQMGVLM 660
Query: 661 SEEEVFELVPDDERQCSACRTTCFLSALTCSCNPERLVCLYHPTDLCPCPMQKKCLRYRY 720
SEEEVFELVPDDERQCSACRTTCFLSALTCSCNPERLVCLYHPTDLCPCPMQKKCLRYRY
Sbjct: 661 SEEEVFELVPDDERQCSACRTTCFLSALTCSCNPERLVCLYHPTDLCPCPMQKKCLRYRY 720
Query: 721 PLEDLPSLLYGVKVRAQSYDTWVSRVTEALSANFNHKKDLIELRVMLEDAEDRKYPENDL 780
PLEDLPSLLYGVKVRAQSYDTWVSRVTEALSANFNHKKDLIELRVMLEDAEDRKYPENDL
Sbjct: 721 PLEDLPSLLYGVKVRAQSYDTWVSRVTEALSANFNHKKDLIELRVMLEDAEDRKYPENDL 780
Query: 781 FRKLRDAVKEAETCASVAQLLLSKKQKHRQSPDSGRTRTKLTVEELKAFVQQLFSLPCVI 840
FRKLRDAVKEAETCASVAQLLLSKKQKHRQSPDSGRTRTKLTVEELKAFVQQLFSLPCVI
Sbjct: 781 FRKLRDAVKEAETCASVAQLLLSKKQKHRQSPDSGRTRTKLTVEELKAFVQQLFSLPCVI 840
Query: 841 SQARQVKNLLDDVEEFHERAQEAMMDETPDSSKLQMLIDMGSSLYVELPELPRLKQELQQ 900
SQARQVKNLLDDVEEFHERAQEAMMDETPDSSKLQMLIDMGSSLYVELPELPRLKQELQQ
Sbjct: 841 SQARQVKNLLDDVEEFHERAQEAMMDETPDSSKLQMLIDMGSSLYVELPELPRLKQELQQ 900
Query: 901 ARWLDEVRLTLSDPQQVTLDVMKKLIDSGVGLAPHHAVEKAMAELQELLTVSERWEEKAK 960
ARWLDEVRLTLSDPQQVTLDVMKKLIDSGVGLAPHHAVEKAMAELQELLTVSERWEEKAK
Sbjct: 901 ARWLDEVRLTLSDPQQVTLDVMKKLIDSGVGLAPHHAVEKAMAELQELLTVSERWEEKAK 960
Query: 961 VCLQARPRHSVASLESIVNEAKNIPAFLPNVLSLKEALQKAREWTAKVEAIQSGSNYAYL 1020
VCLQARPRHSVASLESIVNEAKNIPAFLPNVLSLKEALQKAREWTAKVEAIQSGSNYAYL
Sbjct: 961 VCLQARPRHSVASLESIVNEAKNIPAFLPNVLSLKEALQKAREWTAKVEAIQSGSNYAYL 1020
Query: 1021 EQLESLSAKGRPIPVRLEALPQVESQVAAARAWRERTGRTFLKKNSSHTLLQVLSPRTDI 1080
EQLESLSAKGRPIPVRLEALPQVESQVAAARAWRERTGRTFLKKNSSHTLLQVLSPRTDI
Sbjct: 1021 EQLESLSAKGRPIPVRLEALPQVESQVAAARAWRERTGRTFLKKNSSHTLLQVLSPRTDI 1080
Query: 1081 GVYGSGKNRRKKVKELIEKEKEKDLDLEPLSDLEEGLEETRDTAMVVAVFKEREQKEIEA 1140
GVYGSGKNRRKKVKELIEKEKEKDLDLEPLSDLEEGLEETRDTAMVVAVFKEREQKEIEA
Sbjct: 1081 GVYGSGKNRRKKVKELIEKEKEKDLDLEPLSDLEEGLEETRDTAMVVAVFKEREQKEIEA 1140
Query: 1141 MHSLRAANLAKMTMVDRIEEVKFCICRKTASGFMLQCELCKDWFHNSCVPLPKSSSQKKG 1200
MHSLRAANLAKMTMVDRIEEVKFCICRKTASGFMLQCELCKDWFHNSCVPLPKSSSQKKG
Sbjct: 1141 MHSLRAANLAKMTMVDRIEEVKFCICRKTASGFMLQCELCKDWFHNSCVPLPKSSSQKKG 1200
Query: 1201 SSWQAKEVKFLCPLCMRSRRPRLETILSLLVSLQKLPVRLPEGEALQCLTERAMSWQDRA 1260
SSWQAKEVKFLCPLCMRSRRPRLETILSLLVSLQKLPVRLPEGEALQCLTERAMSWQDRA
Sbjct: 1201 SSWQAKEVKFLCPLCMRSRRPRLETILSLLVSLQKLPVRLPEGEALQCLTERAMSWQDRA 1260
Query: 1261 RQALATDELSSALAKLSVLSQRMVEQAAREKTEKIISAELQKAAANPDLQGHLPSFQQSA 1320
RQALATDELSSALAKLSVLSQRMVEQAAREKTEKIISAELQKAAANPDLQGHLPSFQQSA
Sbjct: 1261 RQALATDELSSALAKLSVLSQRMVEQAAREKTEKIISAELQKAAANPDLQGHLPSFQQSA 1320
Query: 1321 FNRVVSSVSSSPRQTMDYDDEETDSDEDIRETYGYDMKDTASVKSSSSLEPNLFCDEEIP 1380
FNRVVSSVSSSPRQTMDYDDEETDSDEDIRETYGYDMKDTASVKSSSSLEPNLFCDEEIP
Sbjct: 1321 FNRVVSSVSSSPRQTMDYDDEETDSDEDIRETYGYDMKDTASVKSSSSLEPNLFCDEEIP 1380
Query: 1381 IKSEEVVTHMWTAPSFCAEHAYSSASKSCSQ-----GSSTPRKQPRKSPLVPRSLEPPVL 1435
IKSEEVVTHMWTAPSFCAEHAYSSASKSCSQ GSSTPRKQPRKSPLVPRSLEPPVL
Sbjct: 1381 IKSEEVVTHMWTAPSFCAEHAYSSASKSCSQVFFGKGSSTPRKQPRKSPLVPRSLEPPVL 1440
Query: 1436 ELSPGAKAQLEELMMVGDLLEVSLDETQHIWRILQATHPPSEDRFLHIMEDDSMEEKPLK 1495
ELSPGAKAQLEELMMVGDLLEVSLDETQHIWRILQATHPPSEDRFLHIMEDDSMEEKPLK
Sbjct: 1441 ELSPGAKAQLEELMMVGDLLEVSLDETQHIWRILQATHPPSEDRFLHIMEDDSMEEKPLK 1500
Query: 1496 VKGKDSSEKKRKRKLEKVEQLFGEGKQKSKELKKMDKPRKKKLKLGADKSKELNKLAKKL 1555
VKGKDSSEKKRKRKLEKVEQLFGEGKQKSKELKKMDKPRKKKLKLGADKSKELNKLAKKL
Sbjct: 1501 VKGKDSSEKKRKRKLEKVEQLFGEGKQKSKELKKMDKPRKKKLKLGADKSKELNKLAKKL 1560
Query: 1556 AKEEERKKKKEKAAAAKVELVKESTEKKREKKVLDIPSKYDWSGAEESDDENAVCAAQNC 1615
AKEEERKKKKEKAAAAKVELVKESTEKKREKKVLDIPSKYDWSGAEESDDENAVCAAQNC
Sbjct: 1561 AKEEERKKKKEKAAAAKVELVKESTEKKREKKVLDIPSKYDWSGAEESDDENAVCAAQNC 1620
Query: 1616 QRPCKDK 1622
QRPCKDK
Sbjct: 1621 QRPCKDK 1627
>gi|109255243 jumonji, AT rich interactive domain 1C isoform 1 [Homo
sapiens]
Length = 1560
Score = 1498 bits (3879), Expect = 0.0
Identities = 754/1332 (56%), Positives = 960/1332 (72%), Gaps = 67/1332 (5%)
Query: 12 EFVPPPECPVFEPSWEEFTDPLSFIGRIRPLAEKTGICKIRPPKDWQPPFACEVKSFRFT 71
+F+PPPECPVFEPSW EF DPL +I +IRP+AEK+GICKIRPP DWQPPFA EV +FRFT
Sbjct: 7 DFLPPPECPVFEPSWAEFRDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEVDNFRFT 66
Query: 72 PRVQRLNELEAMTRVRLDFLDQLAKFWELQGSTLKIPVVERKILDLYALSKIVASKGGFE 131
PR+QRLNELEA TRV+L++LDQ+AKFWE+QGS+LKIP VER+ILDLY+LSKIV +GG+E
Sbjct: 67 PRIQRLNELEAQTRVKLNYLDQIAKFWEIQGSSLKIPNVERRILDLYSLSKIVVEEGGYE 126
Query: 132 MVTKEKKWSKVGSRLGYLPGKGTGSLLKSHYERILYPYELFQSGVSLMGVQMPNLDLKEK 191
+ K+++W++V RL Y PGK GSLL+SHYERI+YPYE++QSG +L+ D +EK
Sbjct: 127 AICKDRRWARVAQRLNYPPGKNIGSLLRSHYERIVYPYEMYQSGANLVQCNTRPFDNEEK 186
Query: 192 -VEPEVLSTDTQTSPEPGTRMNILPKRTRRVKTQSE--SGDVSRNTELKKLQIFGAGPKV 248
E + S + S +P ++ N +R +R++ E D+ +N ELKKLQI+GAGPK+
Sbjct: 187 DKEYKPHSIPLRQSVQP-SKFNSYGRRAKRLQPDPEPTEEDIEKNPELKKLQIYGAGPKM 245
Query: 249 VGLAMGTKDK------------------EDEVTRRRKVTNRSD----------------A 274
+GL + KDK ++E+ KV + S
Sbjct: 246 MGLGLMAKDKTLRKKDKEGPECPPTVVVKEELGGDVKVESTSPKTFLESKEELSHSPEPC 305
Query: 275 FNMQMRQRKGTLSVNFVDLYVCMFCGRGNNEDKLLLCDGCDDSYHTFCLIPPLPDVPKGD 334
M MR R+ + F++ YVC C RG+ +DKLLLCDGCDD+YH FCL+PPLP++PKG
Sbjct: 306 TKMTMRLRRNHSNAQFIESYVCRMCSRGDEDDKLLLCDGCDDNYHIFCLLPPLPEIPKGV 365
Query: 335 WRCPKCVAEECSKPREAFGFEQAVREYTLQSFGEMADNFKSDYFNMPVHMVPTELVEKEF 394
WRCPKCV EC +P EAFGFEQA REYTLQSFGEMAD+FK+DYFNMPVHMVPTELVEKEF
Sbjct: 366 WRCPKCVMAECKRPPEAFGFEQATREYTLQSFGEMADSFKADYFNMPVHMVPTELVEKEF 425
Query: 395 WRLVSSIEEDVIVEYGADISSKDFGSGFPVKDGRRKILPEEEEYALSGWNLNNMPVLEQS 454
WRLV+SIEEDV VEYGADI SK+FGSGFPV D +R + PEEEEYA SGWNLN MPVLEQS
Sbjct: 426 WRLVNSIEEDVTVEYGADIHSKEFGSGFPVSDSKRHLTPEEEEYATSGWNLNVMPVLEQS 485
Query: 455 VLAHINVDISGMKVPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPSHAAEQL 514
VL HIN DISGMKVPWLYVGM FS+FCWHIEDHWSYSINYLHWGEPKTWYGVPS AAE L
Sbjct: 486 VLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSLAAEHL 545
Query: 515 EEVMRELAPELFESQPDLLHQLVTIMNPNVLMEHGVPVYRTNQCAGEFVVTFPRAYHSGF 574
EEVM++L PELF+SQPDLLHQLVT+MNPN LM HGVPV RTNQCAGEFV+TFPRAYHSGF
Sbjct: 546 EEVMKKLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAYHSGF 605
Query: 575 NQGYNFAEAVNFCTADWLPIGRQCVNHYRRLRRHCVFSHEELIFKMAADPECLDVGLAAM 634
NQGYNFAEAVNFCTADWLP GRQC+ HYRRLRR+CVFSHEELI KMAA PE LD+ LAA
Sbjct: 606 NQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMAACPEKLDLNLAAA 665
Query: 635 VCKELTLMTEEETRLRESVVQMGVLMSEEEVFELVPDDERQCSACRTTCFLSALTCSCNP 694
V KE+ +M +EE RLR+++++ G+ +E E FEL+PDDERQC C+TTCFLSAL C P
Sbjct: 666 VHKEMFIMVQEERRLRKALLEKGITEAEREAFELLPDDERQCIKCKTTCFLSALACYDCP 725
Query: 695 ERLVCLYHPTDLCPCPMQKKCLRYRYPLEDLPSLLYGVKVRAQSYDTWVSRVTEALSANF 754
+ LVCL H DLC C ++ LRYRY L++LP++L+ +KVRA+S+DTW ++V AL
Sbjct: 726 DGLVCLSHINDLCKCSSSRQYLRYRYTLDELPAMLHKLKVRAESFDTWANKVRVALEVED 785
Query: 755 NHKKDLIELRVMLEDAEDRKYPENDLFRKLRDAVKEAETCASVAQLLLSKKQ--KHRQSP 812
K+ L ELR + +A +R++P ++L ++L++ + EAE C S A L+S ++ HR +
Sbjct: 786 GRKRSLEELRALESEARERRFPNSELLQQLKNCLSEAEACVSRALGLVSGQEAGPHRVA- 844
Query: 813 DSGRTRTKLTVEELKAFVQQLFSLPCVISQARQVKNLLDDVEEFHERAQEAMMDETPDSS 872
++T+ EL+AF+ Q+ +LPC + Q VK +L+ VE + A+EA+
Sbjct: 845 -----GLQMTLTELRAFLDQMNNLPCAMHQIGDVKGVLEQVEAYQAEAREALASLPSSPG 899
Query: 873 KLQMLIDMGSSLYVELPELPRLKQELQQARWLDEVRLTLS-DPQQVTLDVMKKLIDSGVG 931
LQ L++ G L VE+PE +L+++++QARWLDEV+ TL+ ++ TL VM+ L+ +G
Sbjct: 900 LLQSLLERGRQLGVEVPEAQQLQRQVEQARWLDEVKRTLAPSARRGTLAVMRGLLVAGAS 959
Query: 932 LAPHHAVEKAMAELQELLTVSERWEEKAKVCLQARPRHSVASLESIVNEAKNIPAFLPNV 991
+AP AV+KA AELQELLT++ERWEEKA +CL+AR +H A+LE+I+ EA+NIP LPN+
Sbjct: 960 VAPSPAVDKAQAELQELLTIAERWEEKAHLCLEARQKHPPATLEAIIREAENIPVHLPNI 1019
Query: 992 LSLKEALQKAREWTAKVEAIQSGSNYAYLEQLESLSAKGRPIPVRLEALPQVESQVAAAR 1051
+LKEAL KAR W A V+ IQ+G +Y L+ LE L A GR +PV LE L Q+E QV A
Sbjct: 1020 QALKEALAKARAWIADVDEIQNGDHYPCLDDLEGLVAVGRDLPVGLEELRQLELQVLTAH 1079
Query: 1052 AWRERTGRTFLKKNSSHTLLQVLSPRTDIGVYGSGKNRRKKVKELIEKEKEKDLDLEPLS 1111
+WRE+ +TFLKKNS +TLL+VL P D G S K R KEL + + +L
Sbjct: 1080 SWREKASKTFLKKNSCYTLLEVLCPCADAG-SDSTKRSRWMEKELGLYKSDTEL------ 1132
Query: 1112 DLEEGLEETRDTAMVVAVFKEREQKEIEAMHSLRAANLAKMTMV----DRIEEVKFCICR 1167
L ++ RD V+ FKE EQKE E + LR N AK + + C+C
Sbjct: 1133 -LGLSAQDLRDPGSVIVAFKEGEQKEKEGILQLRRTNSAKPSPLASSSTASSTTSICVCG 1191
Query: 1168 KTASGF-MLQCELCKDWFHNSCVPLPKSSSQKKGS-------SWQAKEVKFLCPLCMRSR 1219
+ +G LQC+LC+DWFH CV +P+ S + + +W + KFLCPLCMRSR
Sbjct: 1192 QVLAGAGALQCDLCQDWFHGRCVSVPRLLSSPRPNPTSSPLLAWWEWDTKFLCPLCMRSR 1251
Query: 1220 RPRLETILSLLVSLQKLPVRLPEGEALQCLTERAMSWQDRARQALATDELSSALAKLSVL 1279
RPRLETIL+LLV+LQ+LPVRLPEGEALQCLTERA+SWQ RARQALA++++++ L +L+ L
Sbjct: 1252 RPRLETILALLVALQRLPVRLPEGEALQCLTERAISWQGRARQALASEDVTALLGRLAEL 1311
Query: 1280 SQRMVEQAAREK 1291
QR+ + E+
Sbjct: 1312 RQRLQAEPRPEE 1323
>gi|57242796 jumonji, AT rich interactive domain 1B [Homo sapiens]
Length = 1544
Score = 1498 bits (3878), Expect = 0.0
Identities = 733/1276 (57%), Positives = 941/1276 (73%), Gaps = 24/1276 (1%)
Query: 1 MAGVGPGGYAAEFVPPPECPVFEPSWEEFTDPLSFIGRIRPLAEKTGICKIRPPKDWQPP 60
+ G GP G EF+PPPECPVFEPSWEEF DP +FI +IRP+AE+TGICK+RPP DWQPP
Sbjct: 17 LGGPGPLG---EFLPPPECPVFEPSWEEFADPFAFIHKIRPIAEQTGICKVRPPPDWQPP 73
Query: 61 FACEVKSFRFTPRVQRLNELEAMTRVRLDFLDQLAKFWELQGSTLKIPVVERKILDLYAL 120
FAC+V FTPR+QRLNELEA TRV+L+FLDQ+AK+WELQGSTLKIP VERKILDL+ L
Sbjct: 74 FACDVDKLHFTPRIQRLNELEAQTRVKLNFLDQIAKYWELQGSTLKIPHVERKILDLFQL 133
Query: 121 SKIVASKGGFEMVTKEKKWSKVGSRLGYLPGKGTGSLLKSHYERILYPYELFQSGVSLMG 180
+K+VA +GGF +V K++KW+K+ +++G+ PGK GS ++ HYERIL PY LF SG SL
Sbjct: 134 NKLVAEEGGFAVVCKDRKWTKIATKMGFAPGKAVGSHIRGHYERILNPYNLFLSGDSLRC 193
Query: 181 VQMPNL--DLKEKVE-----PEVLSTDTQTSPEPGTRMNILPKRTRRVKTQSESGDVSRN 233
+Q PNL D K+K P+ S + P R + +K + E +R
Sbjct: 194 LQKPNLTTDTKDKEYKPHDIPQRQSVQPSETCPPARRAKRMRAEAMNIKIEPEETTEART 253
Query: 234 TELKKLQIFGAGPKVVGLAMGTKDKEDEVTRRRKVTNRSDAFNMQMRQRKGTLSVNFVDL 293
L++ ++ PK + E R+ ++ + R +K T N VDL
Sbjct: 254 HNLRR-RMGCPTPKCENEKEMKSSIKQEPIERKDYIVENEKEKPKSRSKKAT---NAVDL 309
Query: 294 YVCMFCGRGNNEDKLLLCDGCDDSYHTFCLIPPLPDVPKGDWRCPKCVAEECSKPREAFG 353
YVC+ CG GN+ED+LLLCDGCDDSYHTFCLIPPL DVPKGDWRCPKC+A+ECSKP+EAFG
Sbjct: 310 YVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKCLAQECSKPQEAFG 369
Query: 354 FEQAVREYTLQSFGEMADNFKSDYFNMPVHMVPTELVEKEFWRLVSSIEEDVIVEYGADI 413
FEQA R+YTL++FGEMAD FKSDYFNMPVHMVPTELVEKEFWRLVS+IEEDV VEYGADI
Sbjct: 370 FEQAARDYTLRTFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEEDVTVEYGADI 429
Query: 414 SSKDFGSGFPVKDGRRKILPEEEEYALSGWNLNNMPVLEQSVLAHINVDISGMKVPWLYV 473
+SK+FGSGFPV+DG+ K+ PEEEEY SGWNLNNMPV+EQSVLAHI DI GMK+PWLYV
Sbjct: 430 ASKEFGSGFPVRDGKIKLSPEEEEYLDSGWNLNNMPVMEQSVLAHITADICGMKLPWLYV 489
Query: 474 GMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPSHAAEQLEEVMRELAPELFESQPDLL 533
GMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVP +AAEQLE VM++LAPELF SQPDLL
Sbjct: 490 GMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPGYAAEQLENVMKKLAPELFVSQPDLL 549
Query: 534 HQLVTIMNPNVLMEHGVPVYRTNQCAGEFVVTFPRAYHSGFNQGYNFAEAVNFCTADWLP 593
HQLVTIMNPN LM H VPVYRTNQCAGEFV+TFPRAYHSGFNQG+NFAEAVNFCT DWLP
Sbjct: 550 HQLVTIMNPNTLMTHEVPVYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAVNFCTVDWLP 609
Query: 594 IGRQCVNHYRRLRRHCVFSHEELIFKMAADPECLDVGLAAMVCKELTLMTEEETRLRESV 653
+GRQCV HYR L R+CVFSH+E+I KMA+ + LDV +A+ V K++ +M E+E LRE+V
Sbjct: 610 LGRQCVEHYRLLHRYCVFSHDEMICKMASKADVLDVVVASTVQKDMAIMIEDEKALRETV 669
Query: 654 VQMGVLMSEEEVFELVPDDERQCSACRTTCFLSALTCSCNPERLVCLYHPTDLCPCPMQK 713
++GV+ SE FEL+PDDERQC C+TTCF+SA++CSC P LVCL+H +LC CP K
Sbjct: 670 RKLGVIDSERMDFELLPDDERQCVKCKTTCFMSAISCSCKPGLLVCLHHVKELCSCPPYK 729
Query: 714 KCLRYRYPLEDLPSLLYGVKVRAQSYDTWVSRVTEALSANFNHKKDLIELRVMLEDAEDR 773
LRYRY L+DL ++ +K+RA+SY+ W V EAL A N KK L+ + ++E++E +
Sbjct: 730 YKLRYRYTLDDLYPMMNALKLRAESYNEWALNVNEALEAKINKKKSLVSFKALIEESEMK 789
Query: 774 KYPENDLFRKLRDAVKEAETCASVAQLLLSKKQKHRQSPDSGRTRTKLTVEELKAFVQQL 833
K+P+NDL R LR ++AE CASVAQ LL+ K++ R G+++ +LTV EL+ FV QL
Sbjct: 790 KFPDNDLLRHLRLVTQDAEKCASVAQQLLNGKRQTRYRSGGGKSQNQLTVNELRQFVTQL 849
Query: 834 FSLPCVISQARQVKNLLDDVEEFHERAQEAMMDETPDSSKLQMLIDMGSSLYVELPELPR 893
++LPCV+SQ +K+LL+ VE+F + +Q+ + +ETP +++LQ L+D+ VELP+L
Sbjct: 850 YALPCVLSQTPLLKDLLNRVEDFQQHSQKLLSEETPSAAELQDLLDVSFEFDVELPQLAE 909
Query: 894 LKQELQQARWLDEVRLTLSDPQQVTLDVMKKLIDSGVGLAPHHAVEKAMAELQELLTVSE 953
++ L+QARWL+EV+ DP +TLD M++LID GVGLAP+ AVEKAMA LQELLTVSE
Sbjct: 910 MRIRLEQARWLEEVQQACLDPSSLTLDDMRRLIDLGVGLAPYSAVEKAMARLQELLTVSE 969
Query: 954 RWEEKAKVCLQARPRHSVASLESIVNEAKNIPAFLPNVLSLKEALQKAREWTAKVEAIQS 1013
W++KAK L+ARPRHS+ SL + V E + IPA+LPN +LK+++Q+AR+W VE +Q+
Sbjct: 970 HWDDKAKSLLKARPRHSLNSLATAVKEIEEIPAYLPNGAALKDSVQRARDWLQDVEGLQA 1029
Query: 1014 GSNYAYLEQLESLSAKGRPIPVRLEALPQVESQVAAARAWRERTGRTFLKKNSSHTLLQV 1073
G L+ L L +GR IPV L +LP++E+ VA +AW+E TFL +NS ++LL+V
Sbjct: 1030 GGRVPVLDTLIELVTRGRSIPVHLNSLPRLETLVAEVQAWKECAVNTFLTENSPYSLLEV 1089
Query: 1074 LSPRTDIGVYGSGKNRRKKVKELIEKEKEKDLDLEPLSDLEEGLEETRDTAMVVAVFKER 1133
L PR DIG+ G K +++K+KE + K+K LE LSDLE L E+++TA +A E
Sbjct: 1090 LCPRCDIGLLGL-KRKQRKLKEPLPNGKKKSTKLESLSDLERALTESKETASAMATLGEA 1148
Query: 1134 EQKEIEAMHSLRAANLAKMTMVDRIEEVKFCICRKTASGFMLQCELCKDWFHNSCVPLPK 1193
+E+EA+ SLR AN K+ + ++K C+C+K + M+QCELC+D FH SCV +P
Sbjct: 1149 RLREMEALQSLRLANEGKLLSPLQDVDIKICLCQKAPAAPMIQCELCRDAFHTSCVAVPS 1208
Query: 1194 SSSQKKGSSWQAKEVKFLCPLCMRSRRPRLETILSLLVSLQKLPVRLPEGEALQCLTERA 1253
S + +LCP C RS +P LE IL LL SLQ++ VRLPEG+AL+ + ER
Sbjct: 1209 ISQGLR---------IWLCPHCRRSEKPPLEKILPLLASLQRIRVRLPEGDALRYMIERT 1259
Query: 1254 MSWQDRARQALATDEL 1269
++WQ RA+Q L++ L
Sbjct: 1260 VNWQHRAQQLLSSGNL 1275
Score = 149 bits (375), Expect = 3e-35
Identities = 89/228 (39%), Positives = 122/228 (53%), Gaps = 30/228 (13%)
Query: 1440 GAKAQLEELMMVGDLLEVSLDETQHIWRILQATHPPSEDRFLHIMEDDSMEEKPL---KV 1496
G ++ EL+M LL+VSL E Q +++ L A P++ S E+ K
Sbjct: 1341 GVSPEVNELLMEAQLLQVSLPEIQELYQTLLAKPSPAQQTDRSSPVRPSSEKNDCCRGKR 1400
Query: 1497 KGKDSSEKKRKRKLEKVEQLFGEGKQKSKELKKMDKPRKKKLKLGADKSKELNKLAKKLA 1556
G +S E+K KR+LE+ G ++ + +KKM P+KKK+KL K KL
Sbjct: 1401 DGINSLERKLKRRLERE----GLSSERWERVKKMRTPKKKKIKLSHPKDMNNFKL----- 1451
Query: 1557 KEEERKKKKEKAAAAKVELVKESTEKKREKKVLDIPSKYDWSGAEESDDENAVCAAQNCQ 1616
E ER S E R + +PS +S E+S+DE+A+C A +C
Sbjct: 1452 -ERER-----------------SYELVRSAETHSLPSDTSYSEQEDSEDEDAICPAVSCL 1493
Query: 1617 RPCKDKVDWVQCDGGCDEWFHQVCVGVSPEMAENEDYICINCAKKQGP 1664
+P D+VDWVQCDG C++WFHQVCVGVSPEMAE EDYIC+ C K P
Sbjct: 1494 QPEGDEVDWVQCDGSCNQWFHQVCVGVSPEMAEKEDYICVRCTVKDAP 1541
>gi|33356560 jumonji, AT rich interactive domain 1D isoform 2 [Homo
sapiens]
Length = 1539
Score = 1463 bits (3788), Expect = 0.0
Identities = 736/1330 (55%), Positives = 947/1330 (71%), Gaps = 62/1330 (4%)
Query: 12 EFVPPPECPVFEPSWEEFTDPLSFIGRIRPLAEKTGICKIRPPKDWQPPFACEVKSFRFT 71
EF+PPPECPVFEPSW EF DPL +I +IRP+AEK+GICKIRPP DWQPPFA EV +FRFT
Sbjct: 7 EFLPPPECPVFEPSWAEFQDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEVDNFRFT 66
Query: 72 PRVQRLNELEAMTRVRLDFLDQLAKFWELQGSTLKIPVVERKILDLYALSKIVASKGGFE 131
PRVQRLNELEA TRV+L++LDQ+AKFWE+QGS+LKIP VERKILDLY+LSKIV +GG+E
Sbjct: 67 PRVQRLNELEAQTRVKLNYLDQIAKFWEIQGSSLKIPNVERKILDLYSLSKIVIEEGGYE 126
Query: 132 MVTKEKKWSKVGSRLGYLPGKGTGSLLKSHYERILYPYELFQSGVSLMGVQMPNLD--LK 189
+ K+++W++V RL Y PGK GSLL+SHYERI+YPYE+FQSG + + D +K
Sbjct: 127 AICKDRRWARVAQRLHYPPGKNIGSLLRSHYERIIYPYEMFQSGANHVQCNTHPFDNEVK 186
Query: 190 EKVEPEVLSTDTQTSPEPGTRMNILPKRTRRVKTQSE--SGDVSRNTELKKLQIFGAGPK 247
+K E + S + S +P ++ + +R +R++ E D+ ++ ELKKLQI+G GPK
Sbjct: 187 DK-EYKPHSIPLRQSVQP-SKFSSYSRRAKRLQPDPEPTEEDIEKHPELKKLQIYGPGPK 244
Query: 248 VVGLAMGTKDKEDEVTRRRKVT---------------NRSDAFNMQ-----------MRQ 281
++GL + KDK+ V +KVT N S Q M+
Sbjct: 245 MMGLGLMAKDKDKTV--HKKVTCPPTVTVKDEQSGGGNVSSTLLKQHLSLEPCTKTTMQL 302
Query: 282 RKGTLSVNFVDLYVCMFCGRGNNEDKLLLCDGCDDSYHTFCLIPPLPDVPKGDWRCPKCV 341
RK S F+D Y+C C RG+ +DKLL CDGCDD+YH FCL+PPLP++P+G WRCPKC+
Sbjct: 303 RKNHSSAQFIDSYICQVCSRGDEDDKLLFCDGCDDNYHIFCLLPPLPEIPRGIWRCPKCI 362
Query: 342 AEECSKPREAFGFEQAVREYTLQSFGEMADNFKSDYFNMPVHMVPTELVEKEFWRLVSSI 401
EC +P EAFGFEQA +EY+LQSFGEMAD+FKSDYFNMPVHMVPTELVEKEFWRLVSSI
Sbjct: 363 LAECKQPPEAFGFEQATQEYSLQSFGEMADSFKSDYFNMPVHMVPTELVEKEFWRLVSSI 422
Query: 402 EEDVIVEYGADISSKDFGSGFPVKDGRRKILPEEEEYALSGWNLNNMPVLEQSVLAHINV 461
EEDV VEYGADI SK+FGSGFPV + ++ + PEE+EYA SGWNLN MPVL+QSVL HIN
Sbjct: 423 EEDVTVEYGADIHSKEFGSGFPVSNSKQNLSPEEKEYATSGWNLNVMPVLDQSVLCHINA 482
Query: 462 DISGMKVPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPSHAAEQLEEVMREL 521
DISGMKVPWLYVGM FS+FCWHIEDHWSYSINYLHWGEPKTWYGVPS AAE LEEVM+ L
Sbjct: 483 DISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSLAAEHLEEVMKML 542
Query: 522 APELFESQPDLLHQLVTIMNPNVLMEHGVPVYRTNQCAGEFVVTFPRAYHSGFNQGYNFA 581
PELF+SQPDLLHQLVT+MNPN LM HGVPV RTNQCAGEFV+TFPRAYHSGFNQGYNFA
Sbjct: 543 TPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFA 602
Query: 582 EAVNFCTADWLPIGRQCVNHYRRLRRHCVFSHEELIFKMAADPECLDVGLAAMVCKELTL 641
EAVNFCTADWLP GRQC+ HYRRLRR+CVFSHEELI KMAA PE LD+ LA V KE+ +
Sbjct: 603 EAVNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMAAFPETLDLNLAVAVHKEMFI 662
Query: 642 MTEEETRLRESVVQMGVLMSEEEVFELVPDDERQCSACRTTCFLSALTCSCNPERLVCLY 701
M +EE RLR+++++ GV +E E FEL+PDDERQC C+TTCFLSAL C P+ LVCL
Sbjct: 663 MVQEERRLRKALLEKGVTEAEREAFELLPDDERQCIKCKTTCFLSALACYDCPDGLVCLS 722
Query: 702 HPTDLCPCPMQKKCLRYRYPLEDLPSLLYGVKVRAQSYDTWVSRVTEALSANFNHKKDLI 761
H DLC C ++ LRYRY L++LP++L+ +K+RA+S+DTW ++V AL K+
Sbjct: 723 HINDLCKCSSSRQYLRYRYTLDELPTMLHKLKIRAESFDTWANKVRVALEVEDGRKRSFE 782
Query: 762 ELRVMLEDAEDRKYPENDLFRKLRDAVKEAETCASVAQLLLSKKQKHRQSPDSGRTRTKL 821
ELR + +A +R++P ++L ++L++ + E E C + L+S + +P +L
Sbjct: 783 ELRALESEARERRFPNSELLQRLKNCLSEVEACIAQVLGLVSGQVARMDTP-------QL 835
Query: 822 TVEELKAFVQQLFSLPCVISQARQVKNLLDDVEEFHERAQEAMMDETPDSSKLQMLIDMG 881
T+ EL+ ++Q+ SLPC + Q VK++L+ VE + A+EA+ L+ L++ G
Sbjct: 836 TLTELRVLLEQMGSLPCAMHQIGDVKDVLEQVEAYQAEAREALATLPSSPGLLRSLLERG 895
Query: 882 SSLYVELPELPRLKQELQQARWLDEVRLTLS-DPQQVTLDVMKKLIDSGVGLAPHHAVEK 940
L VE+PE +L+Q+++QA+WLDEV+ L+ + +L +M+ L+ G +A +V+K
Sbjct: 896 QQLGVEVPEAHQLQQQVEQAQWLDEVKQALAPSAHRGSLVIMQGLLVMGAKIASSPSVDK 955
Query: 941 AMAELQELLTVSERWEEKAKVCLQARPRHSVASLESIVNEAKNIPAFLPNVLSLKEALQK 1000
A AELQELLT++ERWEEKA CL+AR +H A+LE+I+ E +NIP LPN+ +LKEAL K
Sbjct: 956 ARAELQELLTIAERWEEKAHFCLEARQKHPPATLEAIIRETENIPVHLPNIQALKEALTK 1015
Query: 1001 AREWTAKVEAIQSGSNYAYLEQLESLSAKGRPIPVRLEALPQVESQVAAARAWRERTGRT 1060
A+ W A V+ IQ+G +Y L+ LE L A GR +PV LE L Q+E QV A +WRE+ +T
Sbjct: 1016 AQAWIADVDEIQNGDHYPCLDDLEGLVAVGRDLPVGLEELRQLELQVLTAHSWREKASKT 1075
Query: 1061 FLKKNSSHTLLQVLSPRTDIGVYGSGKNRRKKVKELIEKEKEKDLDLEPLSDLEEGLEET 1120
FLKKNS +TLL+VL P D GS +R + E + D +L LS ++
Sbjct: 1076 FLKKNSCYTLLEVLCPCADA---GSDSTKRSRWMEKALGLYQCDTELLGLS-----AQDL 1127
Query: 1121 RDTAMVVAVFKEREQKEIEAMHSLRAANLAKMT----MVDRIEEVKFCICRKTASGF-ML 1175
RD V+ FKE EQKE E + LR N AK + + C+C + +G +L
Sbjct: 1128 RDPGSVIVAFKEGEQKEKEGILQLRRTNSAKPSPLAPSLMASSPTSICVCGQVPAGVGVL 1187
Query: 1176 QCELCKDWFHNSCVPLPKSSSQKKGS-------SWQAKEVKFLCPLCMRSRRPRLETILS 1228
QC+LC+DWFH CV +P + K S +W + KFLCPLCMRSRRPRLETIL+
Sbjct: 1188 QCDLCQDWFHGQCVSVPHLLTSPKPSLTSSPLLAWWEWDTKFLCPLCMRSRRPRLETILA 1247
Query: 1229 LLVSLQKLPVRLPEGEALQCLTERAMSWQDRARQALATDELSSALAKLSVLSQRMVEQAA 1288
LLV+LQ+LPVRLPEGEALQCLTERA+ WQDRAR+ALA++++++ L +L+ L Q++ +
Sbjct: 1248 LLVALQRLPVRLPEGEALQCLTERAIGWQDRARKALASEDVTALLRQLAELRQQLQAKPR 1307
Query: 1289 REKTEKIISA 1298
E+ SA
Sbjct: 1308 PEEASVYTSA 1317
Score = 74.3 bits (181), Expect = 9e-13
Identities = 42/106 (39%), Positives = 64/106 (60%), Gaps = 4/106 (3%)
Query: 1423 SPLVPRSLEPPVLELSPGAKAQLEELMMVGDLLEVSLDETQHIWRILQATHPPSEDRFLH 1482
S L+P+ L PVLEL +A LEELMM GDLLEV+LDE IW++LQA PP DR
Sbjct: 1362 SSLLPQ-LTGPVLELPEAIRAPLEELMMEGDLLEVTLDENHSIWQLLQAGQPPDLDRIRT 1420
Query: 1483 IMEDDSMEEKPLKVKGKDSSEKKRKRKLEK---VEQLFGEGKQKSK 1525
++E + E + + + + ++R++K+++ VE L + Q +
Sbjct: 1421 LLELEKFEHQGSRTRSRALERRRRRQKVDQGRNVENLVQQELQSKR 1466
>gi|226442991 jumonji, AT rich interactive domain 1D isoform 1 [Homo
sapiens]
Length = 1570
Score = 1447 bits (3747), Expect = 0.0
Identities = 735/1361 (54%), Positives = 948/1361 (69%), Gaps = 93/1361 (6%)
Query: 12 EFVPPPECPVFEPSWEEFTDPLSFIGRIRPLAEKTGICKIRPPKDWQPPFACEVKSFRFT 71
EF+PPPECPVFEPSW EF DPL +I +IRP+AEK+GICKIRPP DWQPPFA EV +FRFT
Sbjct: 7 EFLPPPECPVFEPSWAEFQDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEVDNFRFT 66
Query: 72 PRVQRLNELEAMTRVRLDFLDQLAKFWELQGSTLKIPVVERKILDLYALSKIVASKGGFE 131
PRVQRLNELEA TRV+L++LDQ+AKFWE+QGS+LKIP VERKILDLY+LSKIV +GG+E
Sbjct: 67 PRVQRLNELEAQTRVKLNYLDQIAKFWEIQGSSLKIPNVERKILDLYSLSKIVIEEGGYE 126
Query: 132 MVTKEKKWSKVGSRLGYLPGKGTGSLLKSHYERILYPYELFQSGVSLMGVQMPNLD--LK 189
+ K+++W++V RL Y PGK GSLL+SHYERI+YPYE+FQSG + + D +K
Sbjct: 127 AICKDRRWARVAQRLHYPPGKNIGSLLRSHYERIIYPYEMFQSGANHVQCNTHPFDNEVK 186
Query: 190 EKVEPEVLSTDTQTSPEPGTRMNILPKRTRRVKTQSE--SGDVSRNTELKKLQIFGAGPK 247
+K E + S + S +P ++ + +R +R++ E D+ ++ ELKKLQI+G GPK
Sbjct: 187 DK-EYKPHSIPLRQSVQP-SKFSSYSRRAKRLQPDPEPTEEDIEKHPELKKLQIYGPGPK 244
Query: 248 VVGLAMGTKDKEDEVTRRRKVT---------NRSDAFNMQ-----------------MRQ 281
++GL + KDK+ V +KVT +S N+ M+
Sbjct: 245 MMGLGLMAKDKDKTV--HKKVTCPPTVTVKDEQSGGGNVSSTLLKQHLSLEPCTKTTMQL 302
Query: 282 RKGTLSVNFVDLYVCMFCGRGNNEDKLLLCDGCDDSYHTFCLIPPLPDVPKGDWRCPKCV 341
RK S F+D Y+C C RG+ +DKLL CDGCDD+YH FCL+PPLP++P+G WRCPKC+
Sbjct: 303 RKNHSSAQFIDSYICQVCSRGDEDDKLLFCDGCDDNYHIFCLLPPLPEIPRGIWRCPKCI 362
Query: 342 AEECSKPREAFGFEQAVREYTLQSFGEMADNFKSDYFNMPVHMVPTELVEKEFWRLVSSI 401
EC +P EAFGFEQA +EY+LQSFGEMAD+FKSDYFNMPVHMVPTELVEKEFWRLVSSI
Sbjct: 363 LAECKQPPEAFGFEQATQEYSLQSFGEMADSFKSDYFNMPVHMVPTELVEKEFWRLVSSI 422
Query: 402 EEDVIVEYGADISSKDFGSGFPVKDGRRKILPEE-------------------------- 435
EEDV VEYGADI SK+FGSGFPV + ++ + PEE
Sbjct: 423 EEDVTVEYGADIHSKEFGSGFPVSNSKQNLSPEEKRQSLTVLTRLISSFWAQAVLPPWPP 482
Query: 436 -----EEYALSGWNLNNMPVLEQSVLAHINVDISGMKVPWLYVGMCFSSFCWHIEDHWSY 490
+EYA SGWNLN MPVL+QSVL HIN DISGMKVPWLYVGM FS+FCWHIEDHWSY
Sbjct: 483 KVLGLQEYATSGWNLNVMPVLDQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSY 542
Query: 491 SINYLHWGEPKTWYGVPSHAAEQLEEVMRELAPELFESQPDLLHQLVTIMNPNVLMEHGV 550
SINYLHWGEPKTWYGVPS AAE LEEVM+ L PELF+SQPDLLHQLVT+MNPN LM HGV
Sbjct: 543 SINYLHWGEPKTWYGVPSLAAEHLEEVMKMLTPELFDSQPDLLHQLVTLMNPNTLMSHGV 602
Query: 551 PVYRTNQCAGEFVVTFPRAYHSGFNQGYNFAEAVNFCTADWLPIGRQCVNHYRRLRRHCV 610
PV RTNQCAGEFV+TFPRAYHSGFNQGYNFAEAVNFCTADWLP GRQC+ HYRRLRR+CV
Sbjct: 603 PVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCV 662
Query: 611 FSHEELIFKMAADPECLDVGLAAMVCKELTLMTEEETRLRESVVQMGVLMSEEEVFELVP 670
FSHEELI KMAA PE LD+ LA V KE+ +M +EE RLR+++++ GV +E E FEL+P
Sbjct: 663 FSHEELICKMAAFPETLDLNLAVAVHKEMFIMVQEERRLRKALLEKGVTEAEREAFELLP 722
Query: 671 DDERQCSACRTTCFLSALTCSCNPERLVCLYHPTDLCPCPMQKKCLRYRYPLEDLPSLLY 730
DDERQC C+TTCFLSAL C P+ LVCL H DLC C ++ LRYRY L++LP++L+
Sbjct: 723 DDERQCIKCKTTCFLSALACYDCPDGLVCLSHINDLCKCSSSRQYLRYRYTLDELPTMLH 782
Query: 731 GVKVRAQSYDTWVSRVTEALSANFNHKKDLIELRVMLEDAEDRKYPENDLFRKLRDAVKE 790
+K+RA+S+DTW ++V AL K+ ELR + +A +R++P ++L ++L++ + E
Sbjct: 783 KLKIRAESFDTWANKVRVALEVEDGRKRSFEELRALESEARERRFPNSELLQRLKNCLSE 842
Query: 791 AETCASVAQLLLSKKQKHRQSPDSGRTRTKLTVEELKAFVQQLFSLPCVISQARQVKNLL 850
E C + L+S + +P +LT+ EL+ ++Q+ SLPC + Q VK++L
Sbjct: 843 VEACIAQVLGLVSGQVARMDTP-------QLTLTELRVLLEQMGSLPCAMHQIGDVKDVL 895
Query: 851 DDVEEFHERAQEAMMDETPDSSKLQMLIDMGSSLYVELPELPRLKQELQQARWLDEVRLT 910
+ VE + A+EA+ L+ L++ G L VE+PE +L+Q+++QA+WLDEV+
Sbjct: 896 EQVEAYQAEAREALATLPSSPGLLRSLLERGQQLGVEVPEAHQLQQQVEQAQWLDEVKQA 955
Query: 911 LS-DPQQVTLDVMKKLIDSGVGLAPHHAVEKAMAELQELLTVSERWEEKAKVCLQARPRH 969
L+ + +L +M+ L+ G +A +V+KA AELQELLT++ERWEEKA CL+AR +H
Sbjct: 956 LAPSAHRGSLVIMQGLLVMGAKIASSPSVDKARAELQELLTIAERWEEKAHFCLEARQKH 1015
Query: 970 SVASLESIVNEAKNIPAFLPNVLSLKEALQKAREWTAKVEAIQSGSNYAYLEQLESLSAK 1029
A+LE+I+ E +NIP LPN+ +LKEAL KA+ W A V+ IQ+G +Y L+ LE L A
Sbjct: 1016 PPATLEAIIRETENIPVHLPNIQALKEALTKAQAWIADVDEIQNGDHYPCLDDLEGLVAV 1075
Query: 1030 GRPIPVRLEALPQVESQVAAARAWRERTGRTFLKKNSSHTLLQVLSPRTDIGVYGSGKNR 1089
GR +PV LE L Q+E QV A +WRE+ +TFLKKNS +TLL+VL P D GS +
Sbjct: 1076 GRDLPVGLEELRQLELQVLTAHSWREKASKTFLKKNSCYTLLEVLCPCADA---GSDSTK 1132
Query: 1090 RKKVKELIEKEKEKDLDLEPLSDLEEGLEETRDTAMVVAVFKEREQKEIEAMHSLRAANL 1149
R + E + D +L LS ++ RD V+ FKE EQKE E + LR N
Sbjct: 1133 RSRWMEKALGLYQCDTELLGLS-----AQDLRDPGSVIVAFKEGEQKEKEGILQLRRTNS 1187
Query: 1150 AKMT----MVDRIEEVKFCICRKTASGF-MLQCELCKDWFHNSCVPLPKSSSQKKGS--- 1201
AK + + C+C + +G +LQC+LC+DWFH CV +P + K S
Sbjct: 1188 AKPSPLAPSLMASSPTSICVCGQVPAGVGVLQCDLCQDWFHGQCVSVPHLLTSPKPSLTS 1247
Query: 1202 ----SWQAKEVKFLCPLCMRSRRPRLETILSLLVSLQKLPVRLPEGEALQCLTERAMSWQ 1257
+W + KFLCPLCMRSRRPRLETIL+LLV+LQ+LPVRLPEGEALQCLTERA+ WQ
Sbjct: 1248 SPLLAWWEWDTKFLCPLCMRSRRPRLETILALLVALQRLPVRLPEGEALQCLTERAIGWQ 1307
Query: 1258 DRARQALATDELSSALAKLSVLSQRMVEQAAREKTEKIISA 1298
DRAR+ALA++++++ L +L+ L Q++ + E+ SA
Sbjct: 1308 DRARKALASEDVTALLRQLAELRQQLQAKPRPEEASVYTSA 1348
Score = 74.3 bits (181), Expect = 9e-13
Identities = 42/106 (39%), Positives = 64/106 (60%), Gaps = 4/106 (3%)
Query: 1423 SPLVPRSLEPPVLELSPGAKAQLEELMMVGDLLEVSLDETQHIWRILQATHPPSEDRFLH 1482
S L+P+ L PVLEL +A LEELMM GDLLEV+LDE IW++LQA PP DR
Sbjct: 1393 SSLLPQ-LTGPVLELPEAIRAPLEELMMEGDLLEVTLDENHSIWQLLQAGQPPDLDRIRT 1451
Query: 1483 IMEDDSMEEKPLKVKGKDSSEKKRKRKLEK---VEQLFGEGKQKSK 1525
++E + E + + + + ++R++K+++ VE L + Q +
Sbjct: 1452 LLELEKFEHQGSRTRSRALERRRRRQKVDQGRNVENLVQQELQSKR 1497
>gi|226443002 jumonji, AT rich interactive domain 1D isoform 3 [Homo
sapiens]
Length = 1482
Score = 1377 bits (3563), Expect = 0.0
Identities = 706/1328 (53%), Positives = 908/1328 (68%), Gaps = 115/1328 (8%)
Query: 12 EFVPPPECPVFEPSWEEFTDPLSFIGRIRPLAEKTGICKIRPPKDWQPPFACEVKSFRFT 71
EF+PPPECPVFEPSW EF DPL +I +IRP+AEK+GICKIRPP DWQPPFA EV +FRFT
Sbjct: 7 EFLPPPECPVFEPSWAEFQDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEVDNFRFT 66
Query: 72 PRVQRLNELEAMTRVRLDFLDQLAKFWELQGSTLKIPVVERKILDLYALSKIVASKGGFE 131
PRVQRLNELEA TRV+L++LDQ+AKFWE+QGS+LKIP VERKILDLY+LSK + F+
Sbjct: 67 PRVQRLNELEAQTRVKLNYLDQIAKFWEIQGSSLKIPNVERKILDLYSLSK-QCNTHPFD 125
Query: 132 MVTKEKKWSKVGSRLGYLPGKGTGSLLKSHYERILYPYELFQSGVSLMGVQMPNLDLKEK 191
K+K++ K H ++ L++
Sbjct: 126 NEVKDKEY-------------------KPH-----------------------SIPLRQS 143
Query: 192 VEPEVLSTDTQTSPEPGTRMNILPKRTRRVKTQSE--SGDVSRNTELKKLQIFGAGPKVV 249
V+P S+ + +R +R++ E D+ ++ ELKKLQI+G GPK++
Sbjct: 144 VQPSKFSSYS--------------RRAKRLQPDPEPTEEDIEKHPELKKLQIYGPGPKMM 189
Query: 250 GLAMGTKDKEDEVTRRRKVT---------------NRSDAFNMQ-----------MRQRK 283
GL + KDK+ V +KVT N S Q M+ RK
Sbjct: 190 GLGLMAKDKDKTV--HKKVTCPPTVTVKDEQSGGGNVSSTLLKQHLSLEPCTKTTMQLRK 247
Query: 284 GTLSVNFVDLYVCMFCGRGNNEDKLLLCDGCDDSYHTFCLIPPLPDVPKGDWRCPKCVAE 343
S F+D Y+C C RG+ +DKLL CDGCDD+YH FCL+PPLP++P+G WRCPKC+
Sbjct: 248 NHSSAQFIDSYICQVCSRGDEDDKLLFCDGCDDNYHIFCLLPPLPEIPRGIWRCPKCILA 307
Query: 344 ECSKPREAFGFEQAVREYTLQSFGEMADNFKSDYFNMPVHMVPTELVEKEFWRLVSSIEE 403
EC +P EAFGFEQA +EY+LQSFGEMAD+FKSDYFNMPVHMVPTELVEKEFWRLVSSIEE
Sbjct: 308 ECKQPPEAFGFEQATQEYSLQSFGEMADSFKSDYFNMPVHMVPTELVEKEFWRLVSSIEE 367
Query: 404 DVIVEYGADISSKDFGSGFPVKDGRRKILPEEEEYALSGWNLNNMPVLEQSVLAHINVDI 463
DV VEYGADI SK+FGSGFPV + ++ + PEE+EYA SGWNLN MPVL+QSVL HIN DI
Sbjct: 368 DVTVEYGADIHSKEFGSGFPVSNSKQNLSPEEKEYATSGWNLNVMPVLDQSVLCHINADI 427
Query: 464 SGMKVPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPSHAAEQLEEVMRELAP 523
SGMKVPWLYVGM FS+FCWHIEDHWSYSINYLHWGEPKTWYGVPS AAE LEEVM+ L P
Sbjct: 428 SGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSLAAEHLEEVMKMLTP 487
Query: 524 ELFESQPDLLHQLVTIMNPNVLMEHGVPVYRTNQCAGEFVVTFPRAYHSGFNQGYNFAEA 583
ELF+SQPDLLHQLVT+MNPN LM HGVPV RTNQCAGEFV+TFPRAYHSGFNQGYNFAEA
Sbjct: 488 ELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEA 547
Query: 584 VNFCTADWLPIGRQCVNHYRRLRRHCVFSHEELIFKMAADPECLDVGLAAMVCKELTLMT 643
VNFCTADWLP GRQC+ HYRRLRR+CVFSHEELI KMAA PE LD+ LA V KE+ +M
Sbjct: 548 VNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMAAFPETLDLNLAVAVHKEMFIMV 607
Query: 644 EEETRLRESVVQMGVLMSEEEVFELVPDDERQCSACRTTCFLSALTCSCNPERLVCLYHP 703
+EE RLR+++++ GV +E E FEL+PDDERQC C+TTCFLSAL C P+ LVCL H
Sbjct: 608 QEERRLRKALLEKGVTEAEREAFELLPDDERQCIKCKTTCFLSALACYDCPDGLVCLSHI 667
Query: 704 TDLCPCPMQKKCLRYRYPLEDLPSLLYGVKVRAQSYDTWVSRVTEALSANFNHKKDLIEL 763
DLC C ++ LRYRY L++LP++L+ +K+RA+S+DTW ++V AL K+ EL
Sbjct: 668 NDLCKCSSSRQYLRYRYTLDELPTMLHKLKIRAESFDTWANKVRVALEVEDGRKRSFEEL 727
Query: 764 RVMLEDAEDRKYPENDLFRKLRDAVKEAETCASVAQLLLSKKQKHRQSPDSGRTRTKLTV 823
R + +A +R++P ++L ++L++ + E E C + L+S + +P +LT+
Sbjct: 728 RALESEARERRFPNSELLQRLKNCLSEVEACIAQVLGLVSGQVARMDTP-------QLTL 780
Query: 824 EELKAFVQQLFSLPCVISQARQVKNLLDDVEEFHERAQEAMMDETPDSSKLQMLIDMGSS 883
EL+ ++Q+ SLPC + Q VK++L+ VE + A+EA+ L+ L++ G
Sbjct: 781 TELRVLLEQMGSLPCAMHQIGDVKDVLEQVEAYQAEAREALATLPSSPGLLRSLLERGQQ 840
Query: 884 LYVELPELPRLKQELQQARWLDEVRLTLS-DPQQVTLDVMKKLIDSGVGLAPHHAVEKAM 942
L VE+PE +L+Q+++QA+WLDEV+ L+ + +L +M+ L+ G +A +V+KA
Sbjct: 841 LGVEVPEAHQLQQQVEQAQWLDEVKQALAPSAHRGSLVIMQGLLVMGAKIASSPSVDKAR 900
Query: 943 AELQELLTVSERWEEKAKVCLQARPRHSVASLESIVNEAKNIPAFLPNVLSLKEALQKAR 1002
AELQELLT++ERWEEKA CL+AR +H A+LE+I+ E +NIP LPN+ +LKEAL KA+
Sbjct: 901 AELQELLTIAERWEEKAHFCLEARQKHPPATLEAIIRETENIPVHLPNIQALKEALTKAQ 960
Query: 1003 EWTAKVEAIQSGSNYAYLEQLESLSAKGRPIPVRLEALPQVESQVAAARAWRERTGRTFL 1062
W A V+ IQ+G +Y L+ LE L A GR +PV LE L Q+E QV A +WRE+ +TFL
Sbjct: 961 AWIADVDEIQNGDHYPCLDDLEGLVAVGRDLPVGLEELRQLELQVLTAHSWREKASKTFL 1020
Query: 1063 KKNSSHTLLQVLSPRTDIGVYGSGKNRRKKVKELIEKEKEKDLDLEPLSDLEEGLEETRD 1122
KKNS +TLL+VL P D GS +R + E + D +L LS ++ RD
Sbjct: 1021 KKNSCYTLLEVLCPCADA---GSDSTKRSRWMEKALGLYQCDTELLGLS-----AQDLRD 1072
Query: 1123 TAMVVAVFKEREQKEIEAMHSLRAANLAKMT----MVDRIEEVKFCICRKTASGF-MLQC 1177
V+ FKE EQKE E + LR N AK + + C+C + +G +LQC
Sbjct: 1073 PGSVIVAFKEGEQKEKEGILQLRRTNSAKPSPLAPSLMASSPTSICVCGQVPAGVGVLQC 1132
Query: 1178 ELCKDWFHNSCVPLPKSSSQKKGS-------SWQAKEVKFLCPLCMRSRRPRLETILSLL 1230
+LC+DWFH CV +P + K S +W + KFLCPLCMRSRRPRLETIL+LL
Sbjct: 1133 DLCQDWFHGQCVSVPHLLTSPKPSLTSSPLLAWWEWDTKFLCPLCMRSRRPRLETILALL 1192
Query: 1231 VSLQKLPVRLPEGEALQCLTERAMSWQDRARQALATDELSSALAKLSVLSQRMVEQAARE 1290
V+LQ+LPVRLPEGEALQCLTERA+ WQDRAR+ALA++++++ L +L+ L Q++ + E
Sbjct: 1193 VALQRLPVRLPEGEALQCLTERAIGWQDRARKALASEDVTALLRQLAELRQQLQAKPRPE 1252
Query: 1291 KTEKIISA 1298
+ SA
Sbjct: 1253 EASVYTSA 1260
Score = 74.3 bits (181), Expect = 9e-13
Identities = 42/106 (39%), Positives = 64/106 (60%), Gaps = 4/106 (3%)
Query: 1423 SPLVPRSLEPPVLELSPGAKAQLEELMMVGDLLEVSLDETQHIWRILQATHPPSEDRFLH 1482
S L+P+ L PVLEL +A LEELMM GDLLEV+LDE IW++LQA PP DR
Sbjct: 1305 SSLLPQ-LTGPVLELPEAIRAPLEELMMEGDLLEVTLDENHSIWQLLQAGQPPDLDRIRT 1363
Query: 1483 IMEDDSMEEKPLKVKGKDSSEKKRKRKLEK---VEQLFGEGKQKSK 1525
++E + E + + + + ++R++K+++ VE L + Q +
Sbjct: 1364 LLELEKFEHQGSRTRSRALERRRRRQKVDQGRNVENLVQQELQSKR 1409
>gi|226442963 jumonji, AT rich interactive domain 1C isoform 2 [Homo
sapiens]
Length = 1379
Score = 1311 bits (3393), Expect = 0.0
Identities = 675/1250 (54%), Positives = 870/1250 (69%), Gaps = 68/1250 (5%)
Query: 95 AKFWELQGSTLKI-PVVERKILDLYALSKIVASKGGFEMVTKEKKWSKVGSRLGYLPGKG 153
A+F + G KI P+ E+ + IV +GG+E + K+++W++V RL Y PGK
Sbjct: 22 AEFRDPLGYIAKIRPIAEKSGICKIRPPAIVVEEGGYEAICKDRRWARVAQRLNYPPGKN 81
Query: 154 TGSLLKSHYERILYPYELFQSGVSLMGVQMPNLDLKEK-VEPEVLSTDTQTSPEPGTRMN 212
GSLL+SHYERI+YPYE++QSG +L+ D +EK E + S + S +P ++ N
Sbjct: 82 IGSLLRSHYERIVYPYEMYQSGANLVQCNTRPFDNEEKDKEYKPHSIPLRQSVQP-SKFN 140
Query: 213 ILPKRTRRVKTQSE--SGDVSRNTELKKLQIFGAGPKVVGLAMGTKDK------------ 258
+R +R++ E D+ +N ELKKLQI+GAGPK++GL + KDK
Sbjct: 141 SYGRRAKRLQPDPEPTEEDIEKNPELKKLQIYGAGPKMMGLGLMAKDKTLRKKDKEGPEC 200
Query: 259 ------EDEVTRRRKVTNRSD----------------AFNMQMRQRKGTLSVNFVDLYVC 296
++E+ KV + S M MR R+ + F++ YVC
Sbjct: 201 PPTVVVKEELGGDVKVESTSPKTFLESKEELSHSPEPCTKMTMRLRRNHSNAQFIESYVC 260
Query: 297 MFCGRGNNEDKLLLCDGCDDSYHTFCLIPPLPDVPKGDWRCPKCVAEECSKPREAFGFEQ 356
C RG+ +DKLLLCDGCDD+YH FCL+PPLP++PKG WRCPKCV EC +P EAFGFEQ
Sbjct: 261 RMCSRGDEDDKLLLCDGCDDNYHIFCLLPPLPEIPKGVWRCPKCVMAECKRPPEAFGFEQ 320
Query: 357 AVREYTLQSFGEMADNFKSDYFNMPVHMVPTELVEKEFWRLVSSIEEDVIVEYGADISSK 416
A REYTLQSFGEMAD+FK+DYFNMPVHMVPTELVEKEFWRLV+SIEEDV VEYGADI SK
Sbjct: 321 ATREYTLQSFGEMADSFKADYFNMPVHMVPTELVEKEFWRLVNSIEEDVTVEYGADIHSK 380
Query: 417 DFGSGFPVKDGRRKILPEEEEYALSGWNLNNMPVLEQSVLAHINVDISGMKVPWLYVGMC 476
+FGSGFPV D +R + PEEEEYA SGWNLN MPVLEQSVL HIN DISGMKVPWLYVGM
Sbjct: 381 EFGSGFPVSDSKRHLTPEEEEYATSGWNLNVMPVLEQSVLCHINADISGMKVPWLYVGMV 440
Query: 477 FSSFCWHIEDHWSYSINYLHWGEPKTWYGVPSHAAEQLEEVMRELAPELFESQPDLLHQL 536
FS+FCWHIEDHWSYSINYLHWGEPKTWYGVPS AAE LEEVM++L PELF+SQPDLLHQL
Sbjct: 441 FSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSLAAEHLEEVMKKLTPELFDSQPDLLHQL 500
Query: 537 VTIMNPNVLMEHGVPVYRTNQCAGEFVVTFPRAYHSGFNQGYNFAEAVNFCTADWLPIGR 596
VT+MNPN LM HGVPV RTNQCAGEFV+TFPRAYHSGFNQGYNFAEAVNFCTADWLP GR
Sbjct: 501 VTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGR 560
Query: 597 QCVNHYRRLRRHCVFSHEELIFKMAADPECLDVGLAAMVCKELTLMTEEETRLRESVVQM 656
QC+ HYRRLRR+CVFSHEELI KMAA PE LD+ LAA V KE+ +M +EE RLR+++++
Sbjct: 561 QCIEHYRRLRRYCVFSHEELICKMAACPEKLDLNLAAAVHKEMFIMVQEERRLRKALLEK 620
Query: 657 GVLMSEEEVFELVPDDERQCSACRTTCFLSALTCSCNPERLVCLYHPTDLCPCPMQKKCL 716
G+ +E E FEL+PDDERQC C+TTCFLSAL C P+ LVCL H DLC C ++ L
Sbjct: 621 GITEAEREAFELLPDDERQCIKCKTTCFLSALACYDCPDGLVCLSHINDLCKCSSSRQYL 680
Query: 717 RYRYPLEDLPSLLYGVKVRAQSYDTWVSRVTEALSANFNHKKDLIELRVMLEDAEDRKYP 776
RYRY L++LP++L+ +KVRA+S+DTW ++V AL K+ L ELR + +A +R++P
Sbjct: 681 RYRYTLDELPAMLHKLKVRAESFDTWANKVRVALEVEDGRKRSLEELRALESEARERRFP 740
Query: 777 ENDLFRKLRDAVKEAETCASVAQLLLSKKQ--KHRQSPDSGRTRTKLTVEELKAFVQQLF 834
++L ++L++ + EAE C S A L+S ++ HR + ++T+ EL+AF+ Q+
Sbjct: 741 NSELLQQLKNCLSEAEACVSRALGLVSGQEAGPHRVA------GLQMTLTELRAFLDQMN 794
Query: 835 SLPCVISQARQVKNLLDDVEEFHERAQEAMMDETPDSSKLQMLIDMGSSLYVELPELPRL 894
+LPC + Q VK +L+ VE + A+EA+ LQ L++ G L VE+PE +L
Sbjct: 795 NLPCAMHQIGDVKGVLEQVEAYQAEAREALASLPSSPGLLQSLLERGRQLGVEVPEAQQL 854
Query: 895 KQELQQARWLDEVRLTLS-DPQQVTLDVMKKLIDSGVGLAPHHAVEKAMAELQELLTVSE 953
+++++QARWLDEV+ TL+ ++ TL VM+ L+ +G +AP AV+KA AELQELLT++E
Sbjct: 855 QRQVEQARWLDEVKRTLAPSARRGTLAVMRGLLVAGASVAPSPAVDKAQAELQELLTIAE 914
Query: 954 RWEEKAKVCLQARPRHSVASLESIVNEAKNIPAFLPNVLSLKEALQKAREWTAKVEAIQS 1013
RWEEKA +CL+AR +H A+LE+I+ EA+NIP LPN+ +LKEAL KAR W A V+ IQ+
Sbjct: 915 RWEEKAHLCLEARQKHPPATLEAIIREAENIPVHLPNIQALKEALAKARAWIADVDEIQN 974
Query: 1014 GSNYAYLEQLESLSAKGRPIPVRLEALPQVESQVAAARAWRERTGRTFLKKNSSHTLLQV 1073
G +Y L+ LE L A GR +PV LE L Q+E QV A +WRE+ +TFLKKNS +TLL+V
Sbjct: 975 GDHYPCLDDLEGLVAVGRDLPVGLEELRQLELQVLTAHSWREKASKTFLKKNSCYTLLEV 1034
Query: 1074 LSPRTDIGVYGSGKNRRKKVKELIEKEKEKDLDLEPLSDLEEGLEETRDTAMVVAVFKER 1133
L P D G S K R KEL + + +L L ++ RD V+ FKE
Sbjct: 1035 LCPCADAG-SDSTKRSRWMEKELGLYKSDTEL-------LGLSAQDLRDPGSVIVAFKEG 1086
Query: 1134 EQKEIEAMHSLRAANLAKMTMV----DRIEEVKFCICRKTASGF-MLQCELCKDWFHNSC 1188
EQKE E + LR N AK + + C+C + +G LQC+LC+DWFH C
Sbjct: 1087 EQKEKEGILQLRRTNSAKPSPLASSSTASSTTSICVCGQVLAGAGALQCDLCQDWFHGRC 1146
Query: 1189 VPLPKSSSQKKGS-------SWQAKEVKFLCPLCMRSRRPRLETILSLLVSLQKLPVRLP 1241
V +P+ S + + +W + KFLCPLCMRSRRPRLETIL+LLV+LQ+LPVRLP
Sbjct: 1147 VSVPRLLSSPRPNPTSSPLLAWWEWDTKFLCPLCMRSRRPRLETILALLVALQRLPVRLP 1206
Query: 1242 EGEALQCLTERAMSWQDRARQALATDELSSALAKLSVLSQRMVEQAAREK 1291
EGEALQCLTERA+SWQ RARQALA++++++ L +L+ L QR+ + E+
Sbjct: 1207 EGEALQCLTERAISWQGRARQALASEDVTALLGRLAELRQRLQAEPRPEE 1256
Score = 82.8 bits (203), Expect = 3e-15
Identities = 33/43 (76%), Positives = 39/43 (90%)
Query: 12 EFVPPPECPVFEPSWEEFTDPLSFIGRIRPLAEKTGICKIRPP 54
+F+PPPECPVFEPSW EF DPL +I +IRP+AEK+GICKIRPP
Sbjct: 7 DFLPPPECPVFEPSWAEFRDPLGYIAKIRPIAEKSGICKIRPP 49
>gi|169218173 PREDICTED: similar to Jumonji, AT rich interactive
domain 1B (RBP2-like), partial [Homo sapiens]
Length = 977
Score = 1241 bits (3210), Expect = 0.0
Identities = 595/967 (61%), Positives = 741/967 (76%), Gaps = 14/967 (1%)
Query: 1 MAGVGPGGYAAEFVPPPECPVFEPSWEEFTDPLSFIGRIRPLAEKTGICKIRPPKDWQPP 60
+ G GP G EF+PPPECPVFEPSWEEF DP +FI +IRP+AE+TGICK+RPP DWQPP
Sbjct: 17 LGGPGPLG---EFLPPPECPVFEPSWEEFADPFAFIHKIRPIAEQTGICKVRPPPDWQPP 73
Query: 61 FACEVKSFRFTPRVQRLNELEAMTRVRLDFLDQLAKFWELQGSTLKIPVVERKILDLYAL 120
FAC+V FTPR+QRLNELEA TRV+L+FLDQ+AK+WELQGSTLKIP VERKILDL+ L
Sbjct: 74 FACDVDKLHFTPRIQRLNELEAQTRVKLNFLDQIAKYWELQGSTLKIPHVERKILDLFQL 133
Query: 121 SKIVASKGGFEMVTKEKKWSKVGSRLGYLPGKGTGSLLKSHYERILYPYELFQSGVSLMG 180
+K+VA +GGF +V K++KW+K+ +++G+ PGK GS ++ HYERIL PY LF SG SL
Sbjct: 134 NKLVAEEGGFAVVCKDRKWTKIATKMGFAPGKAVGSHIRGHYERILNPYNLFLSGDSLRC 193
Query: 181 VQMPNL--DLKEKVE-----PEVLSTDTQTSPEPGTRMNILPKRTRRVKTQSESGDVSRN 233
+Q PNL D K+K P+ S + P R + +K + E +R
Sbjct: 194 LQKPNLTTDTKDKEYKPHDIPQRQSVQPSETCPPARRAKRMRAEAMNIKIEPEETTEART 253
Query: 234 TELKKLQIFGAGPKVVGLAMGTKDKEDEVTRRRKVTNRSDAFNMQMRQRKGTLSVNFVDL 293
L++ ++ PK + E R+ ++ + R +K T N VDL
Sbjct: 254 HNLRR-RMGCPTPKCENEKEMKSSIKQEPIERKDYIVENEKEKPKSRSKKAT---NAVDL 309
Query: 294 YVCMFCGRGNNEDKLLLCDGCDDSYHTFCLIPPLPDVPKGDWRCPKCVAEECSKPREAFG 353
YVC+ CG GN+ED+LLLCDGCDDSYHTFCLIPPL DVPKGDWRCPKC+A+ECSKP+EAFG
Sbjct: 310 YVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKCLAQECSKPQEAFG 369
Query: 354 FEQAVREYTLQSFGEMADNFKSDYFNMPVHMVPTELVEKEFWRLVSSIEEDVIVEYGADI 413
FEQA R+YTL++FGEMAD FKSDYFNMPVHMVPTELVEKEFWRLVS+IEEDV VEYGADI
Sbjct: 370 FEQAARDYTLRTFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEEDVTVEYGADI 429
Query: 414 SSKDFGSGFPVKDGRRKILPEEEEYALSGWNLNNMPVLEQSVLAHINVDISGMKVPWLYV 473
+SK+FGSGFPV+DG+ K+ PEEEEY SGWNLNNMPV+EQSVLAHI DI GMK+PWLYV
Sbjct: 430 ASKEFGSGFPVRDGKIKLSPEEEEYLDSGWNLNNMPVMEQSVLAHITADICGMKLPWLYV 489
Query: 474 GMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPSHAAEQLEEVMRELAPELFESQPDLL 533
GMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVP +AAEQLE VM++LAPELF SQPDLL
Sbjct: 490 GMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPGYAAEQLENVMKKLAPELFVSQPDLL 549
Query: 534 HQLVTIMNPNVLMEHGVPVYRTNQCAGEFVVTFPRAYHSGFNQGYNFAEAVNFCTADWLP 593
HQLVTIMNPN LM H VPVYRTNQCAGEFV+TFPRAYHSGFNQG+NFAEAVNFCT DWLP
Sbjct: 550 HQLVTIMNPNTLMTHEVPVYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAVNFCTVDWLP 609
Query: 594 IGRQCVNHYRRLRRHCVFSHEELIFKMAADPECLDVGLAAMVCKELTLMTEEETRLRESV 653
+GRQCV HYR L R+CVFSH+E+I KMA+ + LDV +A+ V K++ +M E+E LRE+V
Sbjct: 610 LGRQCVEHYRLLHRYCVFSHDEMICKMASKADVLDVVVASTVQKDMAIMIEDEKALRETV 669
Query: 654 VQMGVLMSEEEVFELVPDDERQCSACRTTCFLSALTCSCNPERLVCLYHPTDLCPCPMQK 713
++GV+ SE FEL+PDDERQC C+TTCF+SA++CSC P LVCL+H +LC CP K
Sbjct: 670 RKLGVIDSERMDFELLPDDERQCVKCKTTCFMSAISCSCKPGLLVCLHHVKELCSCPPYK 729
Query: 714 KCLRYRYPLEDLPSLLYGVKVRAQSYDTWVSRVTEALSANFNHKKDLIELRVMLEDAEDR 773
LRYRY L+DL ++ +K+RA+SY+ W V EAL A N KK L+ + ++E++E +
Sbjct: 730 YKLRYRYTLDDLYPMMNALKLRAESYNEWALNVNEALEAKINKKKSLVSFKALIEESEMK 789
Query: 774 KYPENDLFRKLRDAVKEAETCASVAQLLLSKKQKHRQSPDSGRTRTKLTVEELKAFVQQL 833
K+P+NDL R LR ++AE CASVAQ LL+ K++ R G+++ +LTV EL+ FV QL
Sbjct: 790 KFPDNDLLRHLRLVTQDAEKCASVAQQLLNGKRQTRYRSGGGKSQNQLTVNELRQFVTQL 849
Query: 834 FSLPCVISQARQVKNLLDDVEEFHERAQEAMMDETPDSSKLQMLIDMGSSLYVELPELPR 893
++LPCV+SQ +K+LL+ VE+F + +Q+ + +ETP +++LQ L+D+ VELP+L
Sbjct: 850 YALPCVLSQTPLLKDLLNRVEDFQQHSQKLLSEETPSAAELQDLLDVSFEFDVELPQLAE 909
Query: 894 LKQELQQARWLDEVRLTLSDPQQVTLDVMKKLIDSGVGLAPHHAVEKAMAELQELLTVSE 953
++ L+QARWL+EV+ DP +TLD M++LID GVGLAP+ AVEKAMA LQELLTVSE
Sbjct: 910 MRIRLEQARWLEEVQQACLDPSSLTLDDMRRLIDLGVGLAPYSAVEKAMARLQELLTVSE 969
Query: 954 RWEEKAK 960
W++KAK
Sbjct: 970 HWDDKAK 976
>gi|39653317 jumonji domain containing 2D [Homo sapiens]
Length = 523
Score = 154 bits (390), Expect = 5e-37
Identities = 90/243 (37%), Positives = 123/243 (50%), Gaps = 23/243 (9%)
Query: 354 FEQAVREYTLQSFGEMADNFKSDYFNMPVHMVPTELVEKEFWRLVSSIEEDVIVEYGADI 413
F Q ++ + GE S + P H +L E+++W+ + I I YGADI
Sbjct: 86 FTQYHKKKKAMTVGEYRHLANSKKYQTPPHQNFEDL-ERKYWK--NRIYNSPI--YGADI 140
Query: 414 SSKDFGSGFPVKDGRRKILPEEEEYALSGWNLNNMPVLEQSVLAHINVDISGMKVPWLYV 473
S F WNL ++ ++ + V I G+ P+LY
Sbjct: 141 SGSLFDEN------------------TKQWNLGHLGTIQDLLEKECGVVIEGVNTPYLYF 182
Query: 474 GMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPSHAAEQLEEVMRELAPELFESQPDLL 533
GM ++F WH ED YSINYLH GEPKTWY VP ++LE + REL P L
Sbjct: 183 GMWKTTFAWHTEDMDLYSINYLHLGEPKTWYVVPPEHGQRLERLARELFPGSSRGCGAFL 242
Query: 534 HQLVTIMNPNVLMEHGVPVYRTNQCAGEFVVTFPRAYHSGFNQGYNFAEAVNFCTADWLP 593
V +++P VL E+G+P R Q AGEF+VTFP YH+GFN G+N AEA+NF T W+
Sbjct: 243 RHKVALISPTVLKENGIPFNRITQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWID 302
Query: 594 IGR 596
G+
Sbjct: 303 YGK 305
Score = 32.7 bits (73), Expect = 3.1
Identities = 17/45 (37%), Positives = 25/45 (55%), Gaps = 3/45 (6%)
Query: 17 PECPV--FEPSWEEFTDPLSFIGRIRPL-AEKTGICKIRPPKDWQ 58
P C + F P+ EEF D +I + A + G+ KI PPK+W+
Sbjct: 14 PNCNIMIFHPTKEEFNDFDKYIAYMESQGAHRAGLAKIIPPKEWK 58
>gi|239755681 PREDICTED: hypothetical protein [Homo sapiens]
Length = 506
Score = 151 bits (382), Expect = 5e-36
Identities = 78/188 (41%), Positives = 103/188 (54%), Gaps = 18/188 (9%)
Query: 409 YGADISSKDFGSGFPVKDGRRKILPEEEEYALSGWNLNNMPVLEQSVLAHINVDISGMKV 468
YGADIS F E + WNL ++ + + V I G+
Sbjct: 133 YGADISGSLF------------------EESTKQWNLGHLGTILDLLEQECGVVIEGVNT 174
Query: 469 PWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPSHAAEQLEEVMRELAPELFES 528
P+LY GM ++F WH ED YSINYLH+GEPKTWY VP + LE + REL P++
Sbjct: 175 PYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKTWYVVPPEHGQHLERLARELFPDISRG 234
Query: 529 QPDLLHQLVTIMNPNVLMEHGVPVYRTNQCAGEFVVTFPRAYHSGFNQGYNFAEAVNFCT 588
L V +++P VL E+G+P Q AGEF+VTFP YH+GFN G+N AEA+NF T
Sbjct: 235 CEAFLRHKVALISPTVLKENGIPFNCMTQEAGEFMVTFPYGYHAGFNHGFNCAEAINFAT 294
Query: 589 ADWLPIGR 596
W+ G+
Sbjct: 295 PRWIDYGK 302
>gi|239750150 PREDICTED: hypothetical protein [Homo sapiens]
Length = 506
Score = 151 bits (382), Expect = 5e-36
Identities = 78/188 (41%), Positives = 103/188 (54%), Gaps = 18/188 (9%)
Query: 409 YGADISSKDFGSGFPVKDGRRKILPEEEEYALSGWNLNNMPVLEQSVLAHINVDISGMKV 468
YGADIS F E + WNL ++ + + V I G+
Sbjct: 133 YGADISGSLF------------------EESTKQWNLGHLGTILDLLEQECGVVIEGVNT 174
Query: 469 PWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPSHAAEQLEEVMRELAPELFES 528
P+LY GM ++F WH ED YSINYLH+GEPKTWY VP + LE + REL P++
Sbjct: 175 PYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKTWYVVPPEHGQHLERLARELFPDISRG 234
Query: 529 QPDLLHQLVTIMNPNVLMEHGVPVYRTNQCAGEFVVTFPRAYHSGFNQGYNFAEAVNFCT 588
L V +++P VL E+G+P Q AGEF+VTFP YH+GFN G+N AEA+NF T
Sbjct: 235 CEAFLRHKVALISPTVLKENGIPFNCMTQEAGEFMVTFPYGYHAGFNHGFNCAEAINFAT 294
Query: 589 ADWLPIGR 596
W+ G+
Sbjct: 295 PRWIDYGK 302
>gi|239744460 PREDICTED: hypothetical protein [Homo sapiens]
Length = 506
Score = 151 bits (382), Expect = 5e-36
Identities = 78/188 (41%), Positives = 103/188 (54%), Gaps = 18/188 (9%)
Query: 409 YGADISSKDFGSGFPVKDGRRKILPEEEEYALSGWNLNNMPVLEQSVLAHINVDISGMKV 468
YGADIS F E + WNL ++ + + V I G+
Sbjct: 133 YGADISGSLF------------------EESTKQWNLGHLGTILDLLEQECGVVIEGVNT 174
Query: 469 PWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPSHAAEQLEEVMRELAPELFES 528
P+LY GM ++F WH ED YSINYLH+GEPKTWY VP + LE + REL P++
Sbjct: 175 PYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKTWYVVPPEHGQHLERLARELFPDISRG 234
Query: 529 QPDLLHQLVTIMNPNVLMEHGVPVYRTNQCAGEFVVTFPRAYHSGFNQGYNFAEAVNFCT 588
L V +++P VL E+G+P Q AGEF+VTFP YH+GFN G+N AEA+NF T
Sbjct: 235 CEAFLRHKVALISPTVLKENGIPFNCMTQEAGEFMVTFPYGYHAGFNHGFNCAEAINFAT 294
Query: 589 ADWLPIGR 596
W+ G+
Sbjct: 295 PRWIDYGK 302
>gi|169203160 PREDICTED: hypothetical protein [Homo sapiens]
Length = 638
Score = 149 bits (375), Expect = 3e-35
Identities = 78/188 (41%), Positives = 103/188 (54%), Gaps = 18/188 (9%)
Query: 409 YGADISSKDFGSGFPVKDGRRKILPEEEEYALSGWNLNNMPVLEQSVLAHINVDISGMKV 468
YGADIS F E + WNL ++ + + V I G+
Sbjct: 133 YGADISGSLF------------------EESTKQWNLGHLGTILDLLEQECGVVIEGVNT 174
Query: 469 PWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPSHAAEQLEEVMRELAPELFES 528
P+LY GM ++F WH ED YSINYLH+GEPKTWY VP ++LE + REL P
Sbjct: 175 PYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKTWYVVPPEHGQRLECLARELFPGNSRG 234
Query: 529 QPDLLHQLVTIMNPNVLMEHGVPVYRTNQCAGEFVVTFPRAYHSGFNQGYNFAEAVNFCT 588
L V +++P VL ++G+P R Q AGEF+VTFP YH+GFN G+N AEA+NF T
Sbjct: 235 CEGFLRHKVALISPTVLKKNGIPFNRMTQEAGEFMVTFPYGYHAGFNHGFNCAEAINFAT 294
Query: 589 ADWLPIGR 596
W+ G+
Sbjct: 295 PRWIDYGK 302
Score = 31.2 bits (69), Expect = 8.9
Identities = 13/38 (34%), Positives = 23/38 (60%), Gaps = 1/38 (2%)
Query: 22 FEPSWEEFTDPLSFIGRIRPL-AEKTGICKIRPPKDWQ 58
F P+ EEF D +++ + A + G+ K+ PPK+W+
Sbjct: 18 FYPTMEEFADFNTYVAYMESQGAHRAGLAKVIPPKEWK 55
>gi|169203656 PREDICTED: hypothetical protein [Homo sapiens]
Length = 638
Score = 149 bits (375), Expect = 3e-35
Identities = 78/188 (41%), Positives = 103/188 (54%), Gaps = 18/188 (9%)
Query: 409 YGADISSKDFGSGFPVKDGRRKILPEEEEYALSGWNLNNMPVLEQSVLAHINVDISGMKV 468
YGADIS F E + WNL ++ + + V I G+
Sbjct: 133 YGADISGSLF------------------EESTKQWNLGHLGTILDLLEQECGVVIEGVNT 174
Query: 469 PWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPSHAAEQLEEVMRELAPELFES 528
P+LY GM ++F WH ED YSINYLH+GEPKTWY VP ++LE + REL P
Sbjct: 175 PYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKTWYVVPPEHGQRLECLARELFPGNSRG 234
Query: 529 QPDLLHQLVTIMNPNVLMEHGVPVYRTNQCAGEFVVTFPRAYHSGFNQGYNFAEAVNFCT 588
L V +++P VL ++G+P R Q AGEF+VTFP YH+GFN G+N AEA+NF T
Sbjct: 235 CEGFLRHKVALISPTVLKKNGIPFNRMTQEAGEFMVTFPYGYHAGFNHGFNCAEAINFAT 294
Query: 589 ADWLPIGR 596
W+ G+
Sbjct: 295 PRWIDYGK 302
Score = 31.2 bits (69), Expect = 8.9
Identities = 13/38 (34%), Positives = 23/38 (60%), Gaps = 1/38 (2%)
Query: 22 FEPSWEEFTDPLSFIGRIRPL-AEKTGICKIRPPKDWQ 58
F P+ EEF D +++ + A + G+ K+ PPK+W+
Sbjct: 18 FYPTMEEFADFNTYVAYMESQGAHRAGLAKVIPPKEWK 55
>gi|169202387 PREDICTED: hypothetical protein [Homo sapiens]
Length = 638
Score = 149 bits (375), Expect = 3e-35
Identities = 78/188 (41%), Positives = 103/188 (54%), Gaps = 18/188 (9%)
Query: 409 YGADISSKDFGSGFPVKDGRRKILPEEEEYALSGWNLNNMPVLEQSVLAHINVDISGMKV 468
YGADIS F E + WNL ++ + + V I G+
Sbjct: 133 YGADISGSLF------------------EESTKQWNLGHLGTILDLLEQECGVVIEGVNT 174
Query: 469 PWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPSHAAEQLEEVMRELAPELFES 528
P+LY GM ++F WH ED YSINYLH+GEPKTWY VP ++LE + REL P
Sbjct: 175 PYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKTWYVVPPEHGQRLECLARELFPGNSRG 234
Query: 529 QPDLLHQLVTIMNPNVLMEHGVPVYRTNQCAGEFVVTFPRAYHSGFNQGYNFAEAVNFCT 588
L V +++P VL ++G+P R Q AGEF+VTFP YH+GFN G+N AEA+NF T
Sbjct: 235 CEGFLRHKVALISPTVLKKNGIPFNRMTQEAGEFMVTFPYGYHAGFNHGFNCAEAINFAT 294
Query: 589 ADWLPIGR 596
W+ G+
Sbjct: 295 PRWIDYGK 302
Score = 31.2 bits (69), Expect = 8.9
Identities = 13/38 (34%), Positives = 23/38 (60%), Gaps = 1/38 (2%)
Query: 22 FEPSWEEFTDPLSFIGRIRPL-AEKTGICKIRPPKDWQ 58
F P+ EEF D +++ + A + G+ K+ PPK+W+
Sbjct: 18 FYPTMEEFADFNTYVAYMESQGAHRAGLAKVIPPKEWK 55
>gi|11863152 jumonji, AT rich interactive domain 2 protein [Homo
sapiens]
Length = 1246
Score = 147 bits (372), Expect = 7e-35
Identities = 117/393 (29%), Positives = 183/393 (46%), Gaps = 39/393 (9%)
Query: 359 REYTLQSFGEMADNFKSDYFNMPVHMVPTELVEKEFWRLVSSIEEDVIVEYGADISSKDF 418
R +L +F A N S F+ P E +E+E+WRLV + V V G + +
Sbjct: 818 RSVSLTTFYRTARNIMSMCFSK--EPAPAE-IEQEYWRLVEEKDCHVAVHCGK-VDTNTH 873
Query: 419 GSGFPVKDGRRKILPEEEEYALSGWNLNNMPVLEQSVLAHINVDISGMKVPWLYVGMCFS 478
GSGFPV + E ++ GWNL +P S+L H+ + G+ +PWL +GM FS
Sbjct: 874 GSGFPVG--------KSEPFSRHGWNLTVLPNNTGSILRHLGA-VPGVTIPWLNIGMVFS 924
Query: 479 SFCWHIEDHWSYSINYLHWGEPKTWYGVPSHAAEQLEEVMRELAPELFESQPDLLHQLVT 538
+ CW + + I+YLH G WY +P+ +LE+V+ L +L V
Sbjct: 925 TSCWSRDQNHLPYIDYLHTGADCIWYCIPAEEENKLEDVVHTLLQANGTPGLQMLESNVM 984
Query: 539 IMNPNVLMEHGVPVYRTNQCAGEFVVTFPRAYHSGFNQGYNFAEAVNFCTADWLPIGRQC 598
I +P VL + G+ V+RT Q +G+FVV FP ++ S GY+ +E V+F T W +G +
Sbjct: 985 I-SPEVLCKEGIKVHRTVQQSGQFVVCFPGSFVSKVCCGYSVSETVHFATTQWTSMGFET 1043
Query: 599 VNHYRRLRRHCVFSHEELIFKMA-ADPECLDVGLAAMVCKELTLMTEEETRLRESVVQMG 657
+R FS E+L++++A A+ + + + + L + + E R R + + G
Sbjct: 1044 AKEMKRRHIAKPFSMEKLLYQIAQAEAKKENGPTLSTISALLDELRDTELRQRRQLFEAG 1103
Query: 658 VLMS----EEEVFELVPD-------------DERQCSACRTTCFLSALTCSCNPERLVCL 700
+ S + V D ER+C C+ C+LS + N + CL
Sbjct: 1104 LHSSARYGSHDGSSTVADGKKKPRKWLQLETSERRCQICQHLCYLS-MVVQENENVVFCL 1162
Query: 701 YHPTDLCPCPMQKKC----LRYRYPLEDLPSLL 729
L QK C L YRY E + SL+
Sbjct: 1163 --ECALRHVEKQKSCRGLKLMYRYDEEQIISLV 1193
Score = 82.4 bits (202), Expect = 3e-15
Identities = 81/305 (26%), Positives = 136/305 (44%), Gaps = 41/305 (13%)
Query: 7 GGYAAEFVPPPECPVFEPSWEEFTDPLSFIGRIRPLAEKTGICKIRPPKDWQPPFACEVK 66
GG A + E PV PS +EF DPL +I +R EK G+C++ PP DW+P C++
Sbjct: 545 GGGKAGWAAMDEIPVLRPSAKEFHDPLIYIESVRAQVEKFGMCRVIPPPDWRP--ECKLN 602
Query: 67 -SFRFTPRVQRLNELEAMTRVRLDFLDQLAKFWELQGSTL-KIPVVERKILDLYALSKIV 124
RF ++Q +++L + L + K + QG T+ ++P++ LDL +++
Sbjct: 603 DEMRFVTQIQHIHKLGRRWGPNVQRLACIKKHLKSQGITMDELPLIGGCELDLACFFRLI 662
Query: 125 ASKGGFEMVTKEKKWSKVGSRLGYLPGKGTGSL--LKSHYERILYPYELFQSGVSLMGVQ 182
GG + VT KKW+K+ L +P L L+ Y + L Y+ SL +
Sbjct: 663 NEMGGMQQVTDLKKWNKLADML-RIPRTAQDRLAKLQEAYCQYLLSYD------SLSPEE 715
Query: 183 MPNLDLKEKVEPEVLSTDTQTSPEPGTRMNILPKRTRRVKTQSESGDVSRNTELKKLQIF 242
L+ + +E E+L + + P G N K + + ++G I
Sbjct: 716 HRRLEKEVLMEKEIL--EKRKGPLEGHTENDHHKFHPLPRFEPKNG-----------LIH 762
Query: 243 GAGPKVVGLAMGTKDKEDEV------TRRRKVTNRSDAFNMQMRQRKGTLSVNFVDLYVC 296
G P+ G + K EV T RR++ + + + KG L+ D + C
Sbjct: 763 GVAPR-----NGFRSKLKEVGQAQLKTGRRRLFAQEKEVVKEEEEDKGVLN----DFHKC 813
Query: 297 MFCGR 301
++ GR
Sbjct: 814 IYKGR 818
>gi|226442893 jumonji domain containing 2C isoform 3 [Homo sapiens]
Length = 813
Score = 144 bits (363), Expect = 7e-34
Identities = 75/235 (31%), Positives = 127/235 (54%), Gaps = 26/235 (11%)
Query: 362 TLQSFGEMADNFKSDYFNMPVHMVPTELVEKEFWRLVSSIEEDVIVEYGADISSKDFGSG 421
T++ F ++A++ K + P ++ +L E+++W+ ++ + YGADI+ + G
Sbjct: 95 TVKEFRQLANSGK---YCTPRYLDYEDL-ERKYWKNLTFVAPI----YGADINGSIYDEG 146
Query: 422 FPVKDGRRKILPEEEEYALSGWNLNNMPVLEQSVLAHINVDISGMKVPWLYVGMCFSSFC 481
+ WN+ + + V + I G+ P+LY GM ++F
Sbjct: 147 ------------------VDEWNIARLNTVLDVVEEECGISIEGVNTPYLYFGMWKTTFA 188
Query: 482 WHIEDHWSYSINYLHWGEPKTWYGVPSHAAEQLEEVMRELAPELFESQPDLLHQLVTIMN 541
WH ED YSINYLH+GEPK+WY +P ++LE + + P + L +T+++
Sbjct: 189 WHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRHKMTLIS 248
Query: 542 PNVLMEHGVPVYRTNQCAGEFVVTFPRAYHSGFNQGYNFAEAVNFCTADWLPIGR 596
P+VL ++G+P + Q AGEF++TFP YH+GFN G+N AE+ NF T W+ G+
Sbjct: 249 PSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWIDYGK 303
Score = 35.0 bits (79), Expect = 0.62
Identities = 16/46 (34%), Positives = 26/46 (56%), Gaps = 3/46 (6%)
Query: 17 PECPV--FEPSWEEFTDPLSFIGRIRPL-AEKTGICKIRPPKDWQP 59
P C + F PS EEF + ++ + A + G+ K+ PPK+W+P
Sbjct: 12 PSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKP 57
>gi|98986459 jumonji domain containing 2A [Homo sapiens]
Length = 1064
Score = 144 bits (363), Expect = 7e-34
Identities = 65/157 (41%), Positives = 95/157 (60%)
Query: 443 WNLNNMPVLEQSVLAHINVDISGMKVPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKT 502
WN+ + + V + I G+ P+LY GM +SF WH ED YSINYLH+GEPK+
Sbjct: 148 WNIGRLRTILDLVEKESGITIEGVNTPYLYFGMWKTSFAWHTEDMDLYSINYLHFGEPKS 207
Query: 503 WYGVPSHAAEQLEEVMRELAPELFESQPDLLHQLVTIMNPNVLMEHGVPVYRTNQCAGEF 562
WY VP ++LE + + P +S L +T+++P +L ++G+P + Q AGEF
Sbjct: 208 WYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRHKMTLISPLMLKKYGIPFDKVTQEAGEF 267
Query: 563 VVTFPRAYHSGFNQGYNFAEAVNFCTADWLPIGRQCV 599
++TFP YH+GFN G+N AE+ NF T W+ G+Q V
Sbjct: 268 MITFPYGYHAGFNHGFNCAESTNFATRRWIEYGKQAV 304
Score = 33.5 bits (75), Expect = 1.8
Identities = 16/46 (34%), Positives = 24/46 (52%), Gaps = 1/46 (2%)
Query: 15 PPPECPVFEPSWEEFTDPLSFIGRIRPL-AEKTGICKIRPPKDWQP 59
P F P+ EEF + +I I A + G+ K+ PPK+W+P
Sbjct: 10 PSARIMTFYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKP 55
>gi|226442897 jumonji domain containing 2C isoform 4 [Homo sapiens]
Length = 835
Score = 144 bits (363), Expect = 7e-34
Identities = 75/235 (31%), Positives = 127/235 (54%), Gaps = 26/235 (11%)
Query: 362 TLQSFGEMADNFKSDYFNMPVHMVPTELVEKEFWRLVSSIEEDVIVEYGADISSKDFGSG 421
T++ F ++A++ K + P ++ +L E+++W+ ++ + YGADI+ + G
Sbjct: 117 TVKEFRQLANSGK---YCTPRYLDYEDL-ERKYWKNLTFVAPI----YGADINGSIYDEG 168
Query: 422 FPVKDGRRKILPEEEEYALSGWNLNNMPVLEQSVLAHINVDISGMKVPWLYVGMCFSSFC 481
+ WN+ + + V + I G+ P+LY GM ++F
Sbjct: 169 ------------------VDEWNIARLNTVLDVVEEECGISIEGVNTPYLYFGMWKTTFA 210
Query: 482 WHIEDHWSYSINYLHWGEPKTWYGVPSHAAEQLEEVMRELAPELFESQPDLLHQLVTIMN 541
WH ED YSINYLH+GEPK+WY +P ++LE + + P + L +T+++
Sbjct: 211 WHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRHKMTLIS 270
Query: 542 PNVLMEHGVPVYRTNQCAGEFVVTFPRAYHSGFNQGYNFAEAVNFCTADWLPIGR 596
P+VL ++G+P + Q AGEF++TFP YH+GFN G+N AE+ NF T W+ G+
Sbjct: 271 PSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWIDYGK 325
Score = 35.0 bits (79), Expect = 0.62
Identities = 16/46 (34%), Positives = 26/46 (56%), Gaps = 3/46 (6%)
Query: 17 PECPV--FEPSWEEFTDPLSFIGRIRPL-AEKTGICKIRPPKDWQP 59
P C + F PS EEF + ++ + A + G+ K+ PPK+W+P
Sbjct: 34 PSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKP 79
>gi|226442889 jumonji domain containing 2C isoform 2 [Homo sapiens]
Length = 1047
Score = 144 bits (363), Expect = 7e-34
Identities = 75/235 (31%), Positives = 127/235 (54%), Gaps = 26/235 (11%)
Query: 362 TLQSFGEMADNFKSDYFNMPVHMVPTELVEKEFWRLVSSIEEDVIVEYGADISSKDFGSG 421
T++ F ++A++ K + P ++ +L E+++W+ ++ + YGADI+ + G
Sbjct: 95 TVKEFRQLANSGK---YCTPRYLDYEDL-ERKYWKNLTFVAPI----YGADINGSIYDEG 146
Query: 422 FPVKDGRRKILPEEEEYALSGWNLNNMPVLEQSVLAHINVDISGMKVPWLYVGMCFSSFC 481
+ WN+ + + V + I G+ P+LY GM ++F
Sbjct: 147 ------------------VDEWNIARLNTVLDVVEEECGISIEGVNTPYLYFGMWKTTFA 188
Query: 482 WHIEDHWSYSINYLHWGEPKTWYGVPSHAAEQLEEVMRELAPELFESQPDLLHQLVTIMN 541
WH ED YSINYLH+GEPK+WY +P ++LE + + P + L +T+++
Sbjct: 189 WHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRHKMTLIS 248
Query: 542 PNVLMEHGVPVYRTNQCAGEFVVTFPRAYHSGFNQGYNFAEAVNFCTADWLPIGR 596
P+VL ++G+P + Q AGEF++TFP YH+GFN G+N AE+ NF T W+ G+
Sbjct: 249 PSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWIDYGK 303
Score = 35.0 bits (79), Expect = 0.62
Identities = 16/46 (34%), Positives = 26/46 (56%), Gaps = 3/46 (6%)
Query: 17 PECPV--FEPSWEEFTDPLSFIGRIRPL-AEKTGICKIRPPKDWQP 59
P C + F PS EEF + ++ + A + G+ K+ PPK+W+P
Sbjct: 12 PSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKP 57
>gi|109255247 jumonji domain containing 2C isoform 1 [Homo sapiens]
Length = 1056
Score = 144 bits (363), Expect = 7e-34
Identities = 75/235 (31%), Positives = 127/235 (54%), Gaps = 26/235 (11%)
Query: 362 TLQSFGEMADNFKSDYFNMPVHMVPTELVEKEFWRLVSSIEEDVIVEYGADISSKDFGSG 421
T++ F ++A++ K + P ++ +L E+++W+ ++ + YGADI+ + G
Sbjct: 95 TVKEFRQLANSGK---YCTPRYLDYEDL-ERKYWKNLTFVAPI----YGADINGSIYDEG 146
Query: 422 FPVKDGRRKILPEEEEYALSGWNLNNMPVLEQSVLAHINVDISGMKVPWLYVGMCFSSFC 481
+ WN+ + + V + I G+ P+LY GM ++F
Sbjct: 147 ------------------VDEWNIARLNTVLDVVEEECGISIEGVNTPYLYFGMWKTTFA 188
Query: 482 WHIEDHWSYSINYLHWGEPKTWYGVPSHAAEQLEEVMRELAPELFESQPDLLHQLVTIMN 541
WH ED YSINYLH+GEPK+WY +P ++LE + + P + L +T+++
Sbjct: 189 WHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRHKMTLIS 248
Query: 542 PNVLMEHGVPVYRTNQCAGEFVVTFPRAYHSGFNQGYNFAEAVNFCTADWLPIGR 596
P+VL ++G+P + Q AGEF++TFP YH+GFN G+N AE+ NF T W+ G+
Sbjct: 249 PSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWIDYGK 303
Score = 35.0 bits (79), Expect = 0.62
Identities = 16/46 (34%), Positives = 26/46 (56%), Gaps = 3/46 (6%)
Query: 17 PECPV--FEPSWEEFTDPLSFIGRIRPL-AEKTGICKIRPPKDWQP 59
P C + F PS EEF + ++ + A + G+ K+ PPK+W+P
Sbjct: 12 PSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKP 57
>gi|45504380 jumonji domain containing 2B [Homo sapiens]
Length = 1096
Score = 140 bits (352), Expect = 1e-32
Identities = 77/241 (31%), Positives = 123/241 (51%), Gaps = 27/241 (11%)
Query: 360 EYTLQ----SFGEMADNFKSDYFNMPVHMVPTELVEKEFWRLVSSIEEDVIVEYGADISS 415
+Y +Q + GE S+ + P H +L E+++W+ ++ + YGADIS
Sbjct: 85 QYNIQKKAMTVGEYRRLANSEKYCTPRHQDFDDL-ERKYWKNLTFVSPI----YGADISG 139
Query: 416 KDFGSGFPVKDGRRKILPEEEEYALSGWNLNNMPVLEQSVLAHINVDISGMKVPWLYVGM 475
+ ++ WN+ ++ + V I G+ P+LY GM
Sbjct: 140 SLYDDD------------------VAQWNIGSLRTILDMVERECGTIIEGVNTPYLYFGM 181
Query: 476 CFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPSHAAEQLEEVMRELAPELFESQPDLLHQ 535
++F WH ED YSINYLH+GEPK+WY +P ++LE + P + L
Sbjct: 182 WKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAIGFFPGSSQGCDAFLRH 241
Query: 536 LVTIMNPNVLMEHGVPVYRTNQCAGEFVVTFPRAYHSGFNQGYNFAEAVNFCTADWLPIG 595
+T+++P +L ++G+P R Q AGEF++TFP YH+GFN G+N AE+ NF T W+ G
Sbjct: 242 KMTLISPIILKKYGIPFSRITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATLRWIDYG 301
Query: 596 R 596
+
Sbjct: 302 K 302
Score = 37.4 bits (85), Expect = 0.12
Identities = 18/46 (39%), Positives = 26/46 (56%), Gaps = 3/46 (6%)
Query: 17 PECPV--FEPSWEEFTDPLSFIGRIRPL-AEKTGICKIRPPKDWQP 59
P C + F P+ EEF D ++ I A + G+ KI PPK+W+P
Sbjct: 11 PSCKIMTFRPTMEEFKDFNKYVAYIESQGAHRAGLAKIIPPKEWKP 56
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 72.0 bits (175), Expect = 5e-12
Identities = 29/52 (55%), Positives = 37/52 (71%)
Query: 291 VDLYVCMFCGRGNNEDKLLLCDGCDDSYHTFCLIPPLPDVPKGDWRCPKCVA 342
V+ VC CG+ ++ +LLLCD CD SYHT+CL PPL VPKG W+C CV+
Sbjct: 1425 VECIVCEVCGQASDPSRLLLCDDCDISYHTYCLDPPLLTVPKGGWKCKWCVS 1476
Score = 61.6 bits (148), Expect = 6e-09
Identities = 21/46 (45%), Positives = 30/46 (65%)
Query: 295 VCMFCGRGNNEDKLLLCDGCDDSYHTFCLIPPLPDVPKGDWRCPKC 340
VC C + N+ K+L+C+ CD YHTFCL PP+ ++P W+C C
Sbjct: 275 VCQACRKPGNDSKMLVCETCDKGYHTFCLKPPMEELPAHSWKCKAC 320
Score = 38.9 bits (89), Expect = 0.043
Identities = 18/54 (33%), Positives = 22/54 (40%), Gaps = 1/54 (1%)
Query: 296 CMFCGRGNNEDKLLLCDGCDDSYHTFCLIPPLPDVPKGDWRCPKC-VAEECSKP 348
C C L C C YH CL L + W+CP+C V + C KP
Sbjct: 229 CAVCEGPGELCDLFFCTSCGHHYHGACLDTALTARKRAGWQCPECKVCQACRKP 282
>gi|221139764 PHD and ring finger domains 1 [Homo sapiens]
Length = 1648
Score = 71.6 bits (174), Expect = 6e-12
Identities = 28/47 (59%), Positives = 33/47 (70%)
Query: 296 CMFCGRGNNEDKLLLCDGCDDSYHTFCLIPPLPDVPKGDWRCPKCVA 342
C CGR + ED+LLLCDGCD YH CL PPL +VP +W CP+C A
Sbjct: 186 CEVCGRSDREDRLLLCDGCDAGYHMECLDPPLQEVPVDEWFCPECAA 232
>gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo
sapiens]
Length = 4911
Score = 70.1 bits (170), Expect = 2e-11
Identities = 28/47 (59%), Positives = 33/47 (70%)
Query: 295 VCMFCGRGNNEDKLLLCDGCDDSYHTFCLIPPLPDVPKGDWRCPKCV 341
VC CG+ + +LLLCD CD SYHT+CL PPL VPKG W+C CV
Sbjct: 1009 VCEACGKATDPGRLLLCDDCDISYHTYCLDPPLQTVPKGGWKCKWCV 1055
Score = 59.3 bits (142), Expect = 3e-08
Identities = 23/52 (44%), Positives = 30/52 (57%), Gaps = 1/52 (1%)
Query: 295 VCMFCGRGNNEDKLLLCDGCDDSYHTFCLIPPLPDVPKGDWRCPKC-VAEEC 345
VC C + + K+L+CD CD YHTFCL P + VP W+C C + EC
Sbjct: 390 VCQNCKQSGEDSKMLVCDTCDKGYHTFCLQPVMKSVPTNGWKCKNCRICIEC 441
Score = 38.1 bits (87), Expect = 0.073
Identities = 22/58 (37%), Positives = 29/58 (50%), Gaps = 6/58 (10%)
Query: 295 VCMFCGRGNN--EDKLLLCDGCDDSYHTFCLIPPLPDV--PKGDWRCPKC-VAEECSK 347
+C+ CG E +LL C C YH +C+ + V KG WRC +C V E C K
Sbjct: 959 MCVVCGSFGQGAEGRLLACSQCGQCYHPYCVSIKITKVVLSKG-WRCLECTVCEACGK 1015
Score = 35.0 bits (79), Expect = 0.62
Identities = 15/56 (26%), Positives = 23/56 (41%), Gaps = 1/56 (1%)
Query: 296 CMFCGRGNNEDKLLLCDGCDDSYHTFCLIPPLPDVPKGDWRCPKC-VAEECSKPRE 350
C C + C C YH CL + + + W+CP+C V + C + E
Sbjct: 344 CAVCDSPGDLLDQFFCTTCGQHYHGMCLDIAVTPLKRAGWQCPECKVCQNCKQSGE 399
>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
sapiens]
Length = 2168
Score = 69.3 bits (168), Expect = 3e-11
Identities = 29/70 (41%), Positives = 42/70 (60%), Gaps = 1/70 (1%)
Query: 274 AFNMQMRQRKGTLSVNFVDLYVCMFCGRGNNEDKLLLCDGCDDSYHTFCLIPPLPDVPKG 333
A +Q Q+ + + +Y C C +G+NE+ LLLCDGCD HT+C P + +P G
Sbjct: 1913 ALCIQQLQKSIAWEKSIMKVY-CQICRKGDNEELLLLCDGCDKGCHTYCHRPKITTIPDG 1971
Query: 334 DWRCPKCVAE 343
DW CP C+A+
Sbjct: 1972 DWFCPACIAK 1981
Score = 38.1 bits (87), Expect = 0.073
Identities = 30/111 (27%), Positives = 57/111 (51%), Gaps = 1/111 (0%)
Query: 1479 RFLHIMEDDSMEEKPLKVKGKDSSEKKRKRKLEKVEQLFGEGKQKSKELKKMDKPRKKKL 1538
R L E + ++ K + ++E+KRK+K E+++ + + K K + +M+K + +
Sbjct: 905 RKLQKQEQARVAKEAKKQQAIMAAEEKRKQK-EQIKIMKQQEKIKRIQQIRMEKELRAQQ 963
Query: 1539 KLGADKSKELNKLAKKLAKEEERKKKKEKAAAAKVELVKESTEKKREKKVL 1589
L A K K+ KL + E+R K+KE V L + E++R+ +L
Sbjct: 964 ILEAKKKKKEEAANAKLLEAEKRIKEKEMRRQQAVLLKHQERERRRQHMML 1014
Score = 37.4 bits (85), Expect = 0.12
Identities = 31/105 (29%), Positives = 58/105 (55%), Gaps = 15/105 (14%)
Query: 1499 KDSSEKKRKRKLEKVEQL-FGEGKQKSKELKKMDKPRKKKLKLGADKSKELNKLAKKLAK 1557
+ +++ K RKL+K EQ + +K + + ++ RK+K ++ K +E K +++
Sbjct: 896 RQAAQIKLLRKLQKQEQARVAKEAKKQQAIMAAEEKRKQKEQIKIMKQQEKIKRIQQIRM 955
Query: 1558 EEE---------RKKKKEKAAAAKV----ELVKESTEKKREKKVL 1589
E+E +KKKKE+AA AK+ + +KE E +R++ VL
Sbjct: 956 EKELRAQQILEAKKKKKEEAANAKLLEAEKRIKEK-EMRRQQAVL 999
Score = 34.3 bits (77), Expect = 1.1
Identities = 22/91 (24%), Positives = 54/91 (59%), Gaps = 8/91 (8%)
Query: 1505 KRKRKLEKVEQLFGEGKQKSKELKKMDKPRKKKLK----LGADK---SKELNKLAKKLAK 1557
K++ K+++++Q+ E + +++++ + K +K++ L A+K KE+ + L K
Sbjct: 942 KQQEKIKRIQQIRMEKELRAQQILEAKKKKKEEAANAKLLEAEKRIKEKEMRRQQAVLLK 1001
Query: 1558 EEERKKKKEKAAAAK-VELVKESTEKKREKK 1587
+ER+++++ K +E K++ EK+R K+
Sbjct: 1002 HQERERRRQHMMLMKAMEARKKAEEKERLKQ 1032
Score = 32.0 bits (71), Expect = 5.2
Identities = 27/104 (25%), Positives = 50/104 (48%), Gaps = 9/104 (8%)
Query: 1491 EKPLKVKGKDSSEKKRKRKLEKVEQLFGEGKQKSKELKKMDKPRKKKLKLGADKSKELNK 1550
EK L+ + ++KK+K + + L E + K KE+ R+++ L + +E +
Sbjct: 956 EKELRAQQILEAKKKKKEEAANAKLLEAEKRIKEKEM------RRQQAVLLKHQERERRR 1009
Query: 1551 LAKKLAKEEERKKKKEKAAAAKVELVKE---STEKKREKKVLDI 1591
L K E +KK E+ K E E + E+K E++ L++
Sbjct: 1010 QHMMLMKAMEARKKAEEKERLKQEKRDEKRLNKERKLEQRRLEL 1053
Score = 31.6 bits (70), Expect = 6.8
Identities = 23/89 (25%), Positives = 45/89 (50%), Gaps = 8/89 (8%)
Query: 1500 DSSEKKRKRKLEKVEQLFGEGKQKSKELKKMDKPRKKKLKLGADKSKELNKLAKKLAKEE 1559
D+++ K RKL+ E + K L+K+ K + ++ +KE K +A EE
Sbjct: 879 DNADAKLLRKLQAQE--IARQAAQIKLLRKLQKQEQARV------AKEAKKQQAIMAAEE 930
Query: 1560 ERKKKKEKAAAAKVELVKESTEKKREKKV 1588
+RK+K++ + E +K + + EK++
Sbjct: 931 KRKQKEQIKIMKQQEKIKRIQQIRMEKEL 959
>gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo
sapiens]
Length = 1483
Score = 66.2 bits (160), Expect = 3e-10
Identities = 31/81 (38%), Positives = 48/81 (59%), Gaps = 7/81 (8%)
Query: 296 CMFCGRGNNEDKLLLCDGCDDSYHTFCLIPPLPDVPKGDWRCPKCVAEECSKPREAFGFE 355
C C + +DKL+LCD C+ ++H FCL P L +VP G+W+CP C + + R + G
Sbjct: 1187 CKVCRKKGEDDKLILCDECNKAFHLFCLRPALYEVPDGEWQCPAC--QPATARRNSRG-- 1242
Query: 356 QAVREYTLQSFGEMADNFKSD 376
R YT +S E +++ +SD
Sbjct: 1243 ---RNYTEESASEDSEDDESD 1260
>gi|205830434 D4, zinc and double PHD fingers family 1 isoform c
[Homo sapiens]
Length = 332
Score = 65.1 bits (157), Expect = 6e-10
Identities = 25/67 (37%), Positives = 35/67 (52%)
Query: 275 FNMQMRQRKGTLSVNFVDLYVCMFCGRGNNEDKLLLCDGCDDSYHTFCLIPPLPDVPKGD 334
F + M T ++ C CG N+D+LL CD CD YH +CL PP+ + P+G
Sbjct: 252 FTVNMTAAVRTYRWQCIECKSCSLCGTSENDDQLLFCDDCDRGYHMYCLSPPMAEPPEGS 311
Query: 335 WRCPKCV 341
W C C+
Sbjct: 312 WSCHLCL 318
>gi|205830430 D4, zinc and double PHD fingers family 1 isoform a
[Homo sapiens]
Length = 414
Score = 65.1 bits (157), Expect = 6e-10
Identities = 25/67 (37%), Positives = 35/67 (52%)
Query: 275 FNMQMRQRKGTLSVNFVDLYVCMFCGRGNNEDKLLLCDGCDDSYHTFCLIPPLPDVPKGD 334
F + M T ++ C CG N+D+LL CD CD YH +CL PP+ + P+G
Sbjct: 334 FTVNMTAAVRTYRWQCIECKSCSLCGTSENDDQLLFCDDCDRGYHMYCLSPPMAEPPEGS 393
Query: 335 WRCPKCV 341
W C C+
Sbjct: 394 WSCHLCL 400
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.392
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 68,355,691
Number of Sequences: 37866
Number of extensions: 3348787
Number of successful extensions: 23996
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 270
Number of HSP's successfully gapped in prelim test: 651
Number of HSP's that attempted gapping in prelim test: 16032
Number of HSP's gapped (non-prelim): 5768
length of query: 1690
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1574
effective length of database: 13,855,062
effective search space: 21807867588
effective search space used: 21807867588
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.