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Search of human proteins with 166295188
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|166295188 DEP domain containing 1 isoform a [Homo sapiens]
(811 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|166295188 DEP domain containing 1 isoform a [Homo sapiens] 1630 0.0
gi|38488716 DEP domain containing 1 isoform b [Homo sapiens] 627 e-179
gi|223633999 DEP domain containing 1B isoform 1 [Homo sapiens] 317 2e-86
gi|223633997 DEP domain containing 1B isoform 2 [Homo sapiens] 317 2e-86
gi|116256342 novel 58.3 KDA protein isoform 1 [Homo sapiens] 73 1e-12
gi|116256344 novel 58.3 KDA protein isoform 2 [Homo sapiens] 72 2e-12
gi|22748695 DEP domain containing 4 [Homo sapiens] 62 2e-09
gi|67906814 Rho GTPase activating protein 19 [Homo sapiens] 50 1e-05
gi|41281907 StAR-related lipid transfer (START) domain containin... 36 0.13
gi|16445031 StAR-related lipid transfer (START) domain containin... 36 0.13
gi|41281898 StAR-related lipid transfer (START) domain containin... 36 0.13
gi|189571664 DEP domain containing 6 [Homo sapiens] 36 0.16
gi|170763479 MMS19 nucleotide excision repair homolog [Homo sapi... 35 0.28
gi|120953300 leucine-rich repeats and IQ motif containing 1 isof... 35 0.28
gi|120953243 leucine-rich repeats and IQ motif containing 1 isof... 35 0.28
gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III ... 34 0.48
gi|22749359 phosphatidylinositol-3-phosphate 5-kinase type III i... 34 0.48
gi|7657039 tumor necrosis factor receptor superfamily, member 21... 33 0.81
gi|194306650 SET domain and mariner transposase fusion [Homo sap... 33 1.1
gi|59710113 Rho GTPase activating protein 28 isoform a [Homo sap... 33 1.1
gi|59710111 Rho GTPase activating protein 28 isoform b [Homo sap... 33 1.1
gi|215820652 StAR-related lipid transfer (START) domain containi... 33 1.4
gi|215820650 StAR-related lipid transfer (START) domain containi... 33 1.4
gi|31543659 StAR-related lipid transfer (START) domain containin... 33 1.4
gi|7382480 Rho GTPase activating protein 6 isoform 4 [Homo sapiens] 33 1.4
gi|95091988 Rho GTPase activating protein 6 isoform 3 [Homo sapi... 33 1.4
gi|95091875 Rho GTPase activating protein 6 isoform 1 [Homo sapi... 33 1.4
gi|195972871 phospholipase C eta 1 isoform a [Homo sapiens] 32 1.8
gi|57863298 phospholipase C eta 1 isoform b [Homo sapiens] 32 1.8
gi|27262630 nuclear autoantigenic sperm protein isoform 3 [Homo ... 32 1.8
>gi|166295188 DEP domain containing 1 isoform a [Homo sapiens]
Length = 811
Score = 1630 bits (4222), Expect = 0.0
Identities = 811/811 (100%), Positives = 811/811 (100%)
Query: 1 MESQGVPPGPYRATKLWNEVTTSFRAGMPLRKHRQHFKKYGNCFTAGEAVDWLYDLLRNN 60
MESQGVPPGPYRATKLWNEVTTSFRAGMPLRKHRQHFKKYGNCFTAGEAVDWLYDLLRNN
Sbjct: 1 MESQGVPPGPYRATKLWNEVTTSFRAGMPLRKHRQHFKKYGNCFTAGEAVDWLYDLLRNN 60
Query: 61 SNFGPEVTRQQTIQLLRKFLKNHVIEDIKGRWGSENVDDNNQLFRFPATSPLKTLPRRYP 120
SNFGPEVTRQQTIQLLRKFLKNHVIEDIKGRWGSENVDDNNQLFRFPATSPLKTLPRRYP
Sbjct: 61 SNFGPEVTRQQTIQLLRKFLKNHVIEDIKGRWGSENVDDNNQLFRFPATSPLKTLPRRYP 120
Query: 121 ELRKNNIENFSKDKDSIFKLRNLSRRTPKRHGLHLSQENGEKIKHEIINEDQENAIDNRE 180
ELRKNNIENFSKDKDSIFKLRNLSRRTPKRHGLHLSQENGEKIKHEIINEDQENAIDNRE
Sbjct: 121 ELRKNNIENFSKDKDSIFKLRNLSRRTPKRHGLHLSQENGEKIKHEIINEDQENAIDNRE 180
Query: 181 LSQEDVEEVWRYVILIYLQTILGVPSLEEVINPKQVIPQYIMYNMANTSKRGVVILQNKS 240
LSQEDVEEVWRYVILIYLQTILGVPSLEEVINPKQVIPQYIMYNMANTSKRGVVILQNKS
Sbjct: 181 LSQEDVEEVWRYVILIYLQTILGVPSLEEVINPKQVIPQYIMYNMANTSKRGVVILQNKS 240
Query: 241 DDLPHWVLSAMKCLANWPRSNDMNNPTYVGFERDVFRTIADYFLDLPEPLLTFEYYELFV 300
DDLPHWVLSAMKCLANWPRSNDMNNPTYVGFERDVFRTIADYFLDLPEPLLTFEYYELFV
Sbjct: 241 DDLPHWVLSAMKCLANWPRSNDMNNPTYVGFERDVFRTIADYFLDLPEPLLTFEYYELFV 300
Query: 301 NILVVCGYITVSDRSSGIHKIQDDPQSSKFLHLNNLNSFKSTECLLLSLLHREKNKEESD 360
NILVVCGYITVSDRSSGIHKIQDDPQSSKFLHLNNLNSFKSTECLLLSLLHREKNKEESD
Sbjct: 301 NILVVCGYITVSDRSSGIHKIQDDPQSSKFLHLNNLNSFKSTECLLLSLLHREKNKEESD 360
Query: 361 STERLQISNPGFQERCAKKMQLVNLRNRRVSANDIMGGSCHNLIGLSNMHDLSSNSKPRC 420
STERLQISNPGFQERCAKKMQLVNLRNRRVSANDIMGGSCHNLIGLSNMHDLSSNSKPRC
Sbjct: 361 STERLQISNPGFQERCAKKMQLVNLRNRRVSANDIMGGSCHNLIGLSNMHDLSSNSKPRC 420
Query: 421 CSLEGIVDVPGNSSKEASSVFHQSFPNIEGQNNKLFLESKPKQEFLLNLHSEENIQKPFS 480
CSLEGIVDVPGNSSKEASSVFHQSFPNIEGQNNKLFLESKPKQEFLLNLHSEENIQKPFS
Sbjct: 421 CSLEGIVDVPGNSSKEASSVFHQSFPNIEGQNNKLFLESKPKQEFLLNLHSEENIQKPFS 480
Query: 481 AGFKRTSTLTVQDQEELCNGKCKSKQLCRSQSLLLRSSTRRNSYINTPVAEIIMKPNVGQ 540
AGFKRTSTLTVQDQEELCNGKCKSKQLCRSQSLLLRSSTRRNSYINTPVAEIIMKPNVGQ
Sbjct: 481 AGFKRTSTLTVQDQEELCNGKCKSKQLCRSQSLLLRSSTRRNSYINTPVAEIIMKPNVGQ 540
Query: 541 GSTSVQTAMESELGESSATINKRLCKSTIELSENSLLPASSMLTGTQSLLQPHLERVAID 600
GSTSVQTAMESELGESSATINKRLCKSTIELSENSLLPASSMLTGTQSLLQPHLERVAID
Sbjct: 541 GSTSVQTAMESELGESSATINKRLCKSTIELSENSLLPASSMLTGTQSLLQPHLERVAID 600
Query: 601 ALQLCCLLLPPPNRRKLQLLMRMISRMSQNVDMPKLHDAMGTRSLMIHTFSRCVLCCAEE 660
ALQLCCLLLPPPNRRKLQLLMRMISRMSQNVDMPKLHDAMGTRSLMIHTFSRCVLCCAEE
Sbjct: 601 ALQLCCLLLPPPNRRKLQLLMRMISRMSQNVDMPKLHDAMGTRSLMIHTFSRCVLCCAEE 660
Query: 661 VDLDELLAGRLVSFLMDHHQEILQVPSYLQTAVEKHLDYLKKGHIENPGDGLFAPLPTYS 720
VDLDELLAGRLVSFLMDHHQEILQVPSYLQTAVEKHLDYLKKGHIENPGDGLFAPLPTYS
Sbjct: 661 VDLDELLAGRLVSFLMDHHQEILQVPSYLQTAVEKHLDYLKKGHIENPGDGLFAPLPTYS 720
Query: 721 YCKQISAQEFDEQKVSTSQAAIAELLENIIKNRSLPLKEKRKKLKQFQKEYPLIYQKRFP 780
YCKQISAQEFDEQKVSTSQAAIAELLENIIKNRSLPLKEKRKKLKQFQKEYPLIYQKRFP
Sbjct: 721 YCKQISAQEFDEQKVSTSQAAIAELLENIIKNRSLPLKEKRKKLKQFQKEYPLIYQKRFP 780
Query: 781 TTESEAALFGDKPTIKQPMLILRKPKFRSLR 811
TTESEAALFGDKPTIKQPMLILRKPKFRSLR
Sbjct: 781 TTESEAALFGDKPTIKQPMLILRKPKFRSLR 811
>gi|38488716 DEP domain containing 1 isoform b [Homo sapiens]
Length = 527
Score = 627 bits (1617), Expect = e-179
Identities = 303/303 (100%), Positives = 303/303 (100%)
Query: 1 MESQGVPPGPYRATKLWNEVTTSFRAGMPLRKHRQHFKKYGNCFTAGEAVDWLYDLLRNN 60
MESQGVPPGPYRATKLWNEVTTSFRAGMPLRKHRQHFKKYGNCFTAGEAVDWLYDLLRNN
Sbjct: 1 MESQGVPPGPYRATKLWNEVTTSFRAGMPLRKHRQHFKKYGNCFTAGEAVDWLYDLLRNN 60
Query: 61 SNFGPEVTRQQTIQLLRKFLKNHVIEDIKGRWGSENVDDNNQLFRFPATSPLKTLPRRYP 120
SNFGPEVTRQQTIQLLRKFLKNHVIEDIKGRWGSENVDDNNQLFRFPATSPLKTLPRRYP
Sbjct: 61 SNFGPEVTRQQTIQLLRKFLKNHVIEDIKGRWGSENVDDNNQLFRFPATSPLKTLPRRYP 120
Query: 121 ELRKNNIENFSKDKDSIFKLRNLSRRTPKRHGLHLSQENGEKIKHEIINEDQENAIDNRE 180
ELRKNNIENFSKDKDSIFKLRNLSRRTPKRHGLHLSQENGEKIKHEIINEDQENAIDNRE
Sbjct: 121 ELRKNNIENFSKDKDSIFKLRNLSRRTPKRHGLHLSQENGEKIKHEIINEDQENAIDNRE 180
Query: 181 LSQEDVEEVWRYVILIYLQTILGVPSLEEVINPKQVIPQYIMYNMANTSKRGVVILQNKS 240
LSQEDVEEVWRYVILIYLQTILGVPSLEEVINPKQVIPQYIMYNMANTSKRGVVILQNKS
Sbjct: 181 LSQEDVEEVWRYVILIYLQTILGVPSLEEVINPKQVIPQYIMYNMANTSKRGVVILQNKS 240
Query: 241 DDLPHWVLSAMKCLANWPRSNDMNNPTYVGFERDVFRTIADYFLDLPEPLLTFEYYELFV 300
DDLPHWVLSAMKCLANWPRSNDMNNPTYVGFERDVFRTIADYFLDLPEPLLTFEYYELFV
Sbjct: 241 DDLPHWVLSAMKCLANWPRSNDMNNPTYVGFERDVFRTIADYFLDLPEPLLTFEYYELFV 300
Query: 301 NIL 303
NIL
Sbjct: 301 NIL 303
Score = 447 bits (1150), Expect = e-125
Identities = 223/223 (100%), Positives = 223/223 (100%)
Query: 589 LLQPHLERVAIDALQLCCLLLPPPNRRKLQLLMRMISRMSQNVDMPKLHDAMGTRSLMIH 648
LLQPHLERVAIDALQLCCLLLPPPNRRKLQLLMRMISRMSQNVDMPKLHDAMGTRSLMIH
Sbjct: 305 LLQPHLERVAIDALQLCCLLLPPPNRRKLQLLMRMISRMSQNVDMPKLHDAMGTRSLMIH 364
Query: 649 TFSRCVLCCAEEVDLDELLAGRLVSFLMDHHQEILQVPSYLQTAVEKHLDYLKKGHIENP 708
TFSRCVLCCAEEVDLDELLAGRLVSFLMDHHQEILQVPSYLQTAVEKHLDYLKKGHIENP
Sbjct: 365 TFSRCVLCCAEEVDLDELLAGRLVSFLMDHHQEILQVPSYLQTAVEKHLDYLKKGHIENP 424
Query: 709 GDGLFAPLPTYSYCKQISAQEFDEQKVSTSQAAIAELLENIIKNRSLPLKEKRKKLKQFQ 768
GDGLFAPLPTYSYCKQISAQEFDEQKVSTSQAAIAELLENIIKNRSLPLKEKRKKLKQFQ
Sbjct: 425 GDGLFAPLPTYSYCKQISAQEFDEQKVSTSQAAIAELLENIIKNRSLPLKEKRKKLKQFQ 484
Query: 769 KEYPLIYQKRFPTTESEAALFGDKPTIKQPMLILRKPKFRSLR 811
KEYPLIYQKRFPTTESEAALFGDKPTIKQPMLILRKPKFRSLR
Sbjct: 485 KEYPLIYQKRFPTTESEAALFGDKPTIKQPMLILRKPKFRSLR 527
>gi|223633999 DEP domain containing 1B isoform 1 [Homo sapiens]
Length = 529
Score = 317 bits (813), Expect = 2e-86
Identities = 159/311 (51%), Positives = 216/311 (69%), Gaps = 20/311 (6%)
Query: 1 MESQGVPPGPYRATKLWNEVTTSFRAGMPLRKHRQHFKKYGNCFTAGEAVDWLYDLLRNN 60
ME + V PGPYRAT+LWNE FRA MPLRKHR FK Y +CFTA EAVDWL++LLR +
Sbjct: 1 MEHRIVGPGPYRATRLWNETVELFRAKMPLRKHRCRFKSYEHCFTAAEAVDWLHELLRCS 60
Query: 61 SNFGPEVTRQQTIQLLRKFLKNHVIEDIKGRWGSENVDDNNQLFRFPATSPLKTLPRRYP 120
NFGPEVTR+QT+QLL+KFLKNHVIEDIKG+WG E+ +DN L+RFP +SPLK P++ P
Sbjct: 61 QNFGPEVTRKQTVQLLKKFLKNHVIEDIKGKWGEEDFEDNRHLYRFPPSSPLKPYPKKPP 120
Query: 121 ELRK-------NNI-ENFSKDKDSIFKLRNLSRRTPKRHGLHLSQENGEKIKHEIINEDQ 172
+ N++ S++ + + S KRH + + + ++ H
Sbjct: 121 NQKDVIKFPEWNDLPPGTSQENIPVRPVVMNSEMWYKRHSIAIGEVPACRLVH------- 173
Query: 173 ENAIDNRELSQEDVEEVWRYVILIYLQTILGVPSLEEVINPKQVIPQYIMYNMANTSKRG 232
R+L++ +VEE+W+ + L YLQ ILG+ SLEEV++ K V ++I++N+ + SK+G
Sbjct: 174 -----RRQLTEANVEEIWKSMTLSYLQKILGLDSLEEVLDVKLVNSKFIIHNVYSVSKQG 228
Query: 233 VVILQNKSDDLPHWVLSAMKCLANWPRSNDMNNPTYVGFERDVFRTIADYFLDLPEPLLT 292
VVIL +KS +LPHWVLSAMKCLANWP +D+ P Y+GFE+DVF+TIADY+ L EPLLT
Sbjct: 229 VVILDDKSKELPHWVLSAMKCLANWPNCSDLKQPMYLGFEKDVFKTIADYYGHLKEPLLT 288
Query: 293 FEYYELFVNIL 303
F ++ FV++L
Sbjct: 289 FHLFDAFVSVL 299
Score = 236 bits (601), Expect = 8e-62
Identities = 119/213 (55%), Positives = 159/213 (74%), Gaps = 2/213 (0%)
Query: 595 ERVAIDALQLCCLLLPPPNRRKLQLLMRMISRMSQNVDMPKLHDAMGTRSLMIHTFSRCV 654
E+VA++A Q+CCLLLPP NRRKLQLLMRM++R+ N +MP L D GTR+LM+ TFSRC+
Sbjct: 305 EKVAVEAFQICCLLLPPENRRKLQLLMRMMARICLNKEMPPLCDGFGTRTLMVQTFSRCI 364
Query: 655 LCCAEEVDLDELLAGRLVSFLMDHHQEILQVPSYLQTAVEKHLDYLKKGHIENPGDGLFA 714
LC +EVDLDELLA RLV+FLMD++QEIL+VP LQT++E+ + +L++ I+ PG +
Sbjct: 365 LCSKDEVDLDELLAARLVTFLMDNYQEILKVPLALQTSIEERVAHLRRVQIKYPGADMDI 424
Query: 715 PLPTYSYCKQISAQEFDEQKVSTSQAAIAELLENIIKNRSLPLKEKRKKLKQFQKEYPLI 774
L S+C+QIS +EF+ Q+ SQ +A LLE +I + L KEK+KKLKQFQK YP +
Sbjct: 425 TLSAPSFCRQISPEEFEYQRSYGSQEPLAALLEEVITDAKLSNKEKKKKLKQFQKSYPEV 484
Query: 775 YQKRFPTTESEAALFGDKPTIKQPMLI--LRKP 805
YQ+RFPT ES A LF +KP K +L+ L+KP
Sbjct: 485 YQERFPTPESAALLFPEKPKPKPQLLMWALKKP 517
>gi|223633997 DEP domain containing 1B isoform 2 [Homo sapiens]
Length = 467
Score = 317 bits (813), Expect = 2e-86
Identities = 159/311 (51%), Positives = 216/311 (69%), Gaps = 20/311 (6%)
Query: 1 MESQGVPPGPYRATKLWNEVTTSFRAGMPLRKHRQHFKKYGNCFTAGEAVDWLYDLLRNN 60
ME + V PGPYRAT+LWNE FRA MPLRKHR FK Y +CFTA EAVDWL++LLR +
Sbjct: 1 MEHRIVGPGPYRATRLWNETVELFRAKMPLRKHRCRFKSYEHCFTAAEAVDWLHELLRCS 60
Query: 61 SNFGPEVTRQQTIQLLRKFLKNHVIEDIKGRWGSENVDDNNQLFRFPATSPLKTLPRRYP 120
NFGPEVTR+QT+QLL+KFLKNHVIEDIKG+WG E+ +DN L+RFP +SPLK P++ P
Sbjct: 61 QNFGPEVTRKQTVQLLKKFLKNHVIEDIKGKWGEEDFEDNRHLYRFPPSSPLKPYPKKPP 120
Query: 121 ELRK-------NNI-ENFSKDKDSIFKLRNLSRRTPKRHGLHLSQENGEKIKHEIINEDQ 172
+ N++ S++ + + S KRH + + + ++ H
Sbjct: 121 NQKDVIKFPEWNDLPPGTSQENIPVRPVVMNSEMWYKRHSIAIGEVPACRLVH------- 173
Query: 173 ENAIDNRELSQEDVEEVWRYVILIYLQTILGVPSLEEVINPKQVIPQYIMYNMANTSKRG 232
R+L++ +VEE+W+ + L YLQ ILG+ SLEEV++ K V ++I++N+ + SK+G
Sbjct: 174 -----RRQLTEANVEEIWKSMTLSYLQKILGLDSLEEVLDVKLVNSKFIIHNVYSVSKQG 228
Query: 233 VVILQNKSDDLPHWVLSAMKCLANWPRSNDMNNPTYVGFERDVFRTIADYFLDLPEPLLT 292
VVIL +KS +LPHWVLSAMKCLANWP +D+ P Y+GFE+DVF+TIADY+ L EPLLT
Sbjct: 229 VVILDDKSKELPHWVLSAMKCLANWPNCSDLKQPMYLGFEKDVFKTIADYYGHLKEPLLT 288
Query: 293 FEYYELFVNIL 303
F ++ FV++L
Sbjct: 289 FHLFDAFVSVL 299
Score = 146 bits (369), Expect = 7e-35
Identities = 68/108 (62%), Positives = 91/108 (84%)
Query: 595 ERVAIDALQLCCLLLPPPNRRKLQLLMRMISRMSQNVDMPKLHDAMGTRSLMIHTFSRCV 654
E+VA++A Q+CCLLLPP NRRKLQLLMRM++R+ N +MP L D GTR+LM+ TFSRC+
Sbjct: 305 EKVAVEAFQICCLLLPPENRRKLQLLMRMMARICLNKEMPPLCDGFGTRTLMVQTFSRCI 364
Query: 655 LCCAEEVDLDELLAGRLVSFLMDHHQEILQVPSYLQTAVEKHLDYLKK 702
LC +EVDLDELLA RLV+FLMD++QEIL+VP LQT++E+ + +L++
Sbjct: 365 LCSKDEVDLDELLAARLVTFLMDNYQEILKVPLALQTSIEERVAHLRR 412
Score = 52.0 bits (123), Expect = 2e-06
Identities = 36/98 (36%), Positives = 55/98 (56%), Gaps = 11/98 (11%)
Query: 718 TYSYCKQISAQEFDEQKVSTSQAAIAELLENIIKNRSLPL------KEKRKKLK--QFQK 769
T+S C S E D ++ ++ + L++N + +PL +E+ L+ QFQK
Sbjct: 359 TFSRCILCSKDEVDLDELLAARL-VTFLMDNYQEILKVPLALQTSIEERVAHLRRVQFQK 417
Query: 770 EYPLIYQKRFPTTESEAALFGDKPTIKQPMLI--LRKP 805
YP +YQ+RFPT ES A LF +KP K +L+ L+KP
Sbjct: 418 SYPEVYQERFPTPESAALLFPEKPKPKPQLLMWALKKP 455
>gi|116256342 novel 58.3 KDA protein isoform 1 [Homo sapiens]
Length = 511
Score = 72.8 bits (177), Expect = 1e-12
Identities = 59/272 (21%), Positives = 127/272 (46%), Gaps = 37/272 (13%)
Query: 7 PPG------PYRATKLWNEVTTSFRAGMPLRKHRQHFKKYGNCFTAGEAVDWLYDLLRNN 60
PPG P+ AT +W+ + + + + ++K R K++ +CF EAVD ++ L N
Sbjct: 23 PPGFSVAQKPFGATYVWSSIINTLQTQVEVKKRRHRLKRHNDCFVGSEAVDVIFSHLIQN 82
Query: 61 SNFGP-EVTRQQTIQLLRKFLKNHVIEDIKGR-WGSEN----VDDNNQLFRFPATSPLKT 114
FG ++ R + +++ + + V E + + +G + D + L+RF T
Sbjct: 83 KYFGDVDIPRAKVVRVCQALMDYKVFEAVPTKVFGKDKKPTFEDSSCSLYRF------TT 136
Query: 115 LPRRYPEL-RKNNIENFSKDKDSIFKLRNLSRRTPKRHGLHLSQENGEKIKHEIINEDQE 173
+P + +L ++N + + ++ D++FK ++ + ++ E + + N
Sbjct: 137 IPNQDSQLGKENKLYSPARYADALFKSSDIRSAS--------LEDLWENLSLKPANSPHV 188
Query: 174 NAIDNRELSQEDVEEVWRYVILIYLQTILGVPSLEEVINPKQVIP-------QYIMYNMA 226
N + LS + + EVW+ + L ++ +P L+ ++ ++ +P Q M N +
Sbjct: 189 NI--SATLSPQVINEVWQEETIGRLLQLVDLPLLDSLLKQQEAVPKIPQPKRQSTMVNSS 246
Query: 227 NTSKRGVVILQNKSDDLPHWVLSAMKCLANWP 258
N RG++ + S + W+ +A+ CL P
Sbjct: 247 NYLDRGILKAYSDSQE-DEWLSAAIDCLEYLP 277
Score = 72.4 bits (176), Expect = 2e-12
Identities = 53/200 (26%), Positives = 95/200 (47%), Gaps = 11/200 (5%)
Query: 580 SSMLTGTQSLLQPHLERVAIDALQLCCLLLPPPNRRKLQLLMRMISRMSQNVDMPKLHDA 639
S + G LL +A++A QL LL NR + + L+ ++ ++ N KL
Sbjct: 321 SDVHNGIAELLVNGKTEIALEATQLLLKLLDFQNREEFRRLLYFMA-VAANPSEFKLQKE 379
Query: 640 MGTRSLMIHTFSRCVLCCAEEVDLDELLAGRLVSFLMDHHQEILQVPSYLQTAVEKHLDY 699
R ++ FS+ ++ + +L + LV FLMDH +++ ++P L V L
Sbjct: 380 SDNRMVVKRIFSKAIV---DNKNLSKGKTDLLVLFLMDHQKDVFKIPGTLHKIVSVKLMA 436
Query: 700 LKKGHIENPGDGLFAPLPTYSYCKQISAQEFDEQKVSTSQAAIAELLENIIKNRSLPLKE 759
++ G N G Y YC++I +++ T++ + LL+ + ++ L KE
Sbjct: 437 IQNGRDPNRDAG-------YIYCQRIDQRDYSNNTEKTTKDELLNLLKTLDEDSKLSAKE 489
Query: 760 KRKKLKQFQKEYPLIYQKRF 779
K+K L QF K +P I+ + F
Sbjct: 490 KKKLLGQFYKCHPDIFIEHF 509
>gi|116256344 novel 58.3 KDA protein isoform 2 [Homo sapiens]
Length = 502
Score = 72.4 bits (176), Expect = 2e-12
Identities = 53/200 (26%), Positives = 95/200 (47%), Gaps = 11/200 (5%)
Query: 580 SSMLTGTQSLLQPHLERVAIDALQLCCLLLPPPNRRKLQLLMRMISRMSQNVDMPKLHDA 639
S + G LL +A++A QL LL NR + + L+ ++ ++ N KL
Sbjct: 312 SDVHNGIAELLVNGKTEIALEATQLLLKLLDFQNREEFRRLLYFMA-VAANPSEFKLQKE 370
Query: 640 MGTRSLMIHTFSRCVLCCAEEVDLDELLAGRLVSFLMDHHQEILQVPSYLQTAVEKHLDY 699
R ++ FS+ ++ + +L + LV FLMDH +++ ++P L V L
Sbjct: 371 SDNRMVVKRIFSKAIV---DNKNLSKGKTDLLVLFLMDHQKDVFKIPGTLHKIVSVKLMA 427
Query: 700 LKKGHIENPGDGLFAPLPTYSYCKQISAQEFDEQKVSTSQAAIAELLENIIKNRSLPLKE 759
++ G N G Y YC++I +++ T++ + LL+ + ++ L KE
Sbjct: 428 IQNGRDPNRDAG-------YIYCQRIDQRDYSNNTEKTTKDELLNLLKTLDEDSKLSAKE 480
Query: 760 KRKKLKQFQKEYPLIYQKRF 779
K+K L QF K +P I+ + F
Sbjct: 481 KKKLLGQFYKCHPDIFIEHF 500
Score = 71.6 bits (174), Expect = 3e-12
Identities = 56/263 (21%), Positives = 124/263 (47%), Gaps = 31/263 (11%)
Query: 10 PYRATKLWNEVTTSFRAGMPLRKHRQHFKKYGNCFTAGEAVDWLYDLLRNNSNFGP-EVT 68
P+ AT +W+ + + + + ++K R K++ +CF EAVD ++ L N FG ++
Sbjct: 23 PFGATYVWSSIINTLQTQVEVKKRRHRLKRHNDCFVGSEAVDVIFSHLIQNKYFGDVDIP 82
Query: 69 RQQTIQLLRKFLKNHVIEDIKGR-WGSEN----VDDNNQLFRFPATSPLKTLPRRYPEL- 122
R + +++ + + V E + + +G + D + L+RF T+P + +L
Sbjct: 83 RAKVVRVCQALMDYKVFEAVPTKVFGKDKKPTFEDSSCSLYRF------TTIPNQDSQLG 136
Query: 123 RKNNIENFSKDKDSIFKLRNLSRRTPKRHGLHLSQENGEKIKHEIINEDQENAIDNRELS 182
++N + + ++ D++FK ++ + ++ E + + N N + LS
Sbjct: 137 KENKLYSPARYADALFKSSDIRSAS--------LEDLWENLSLKPANSPHVNI--SATLS 186
Query: 183 QEDVEEVWRYVILIYLQTILGVPSLEEVINPKQVIP-------QYIMYNMANTSKRGVVI 235
+ + EVW+ + L ++ +P L+ ++ ++ +P Q M N +N RG++
Sbjct: 187 PQVINEVWQEETIGRLLQLVDLPLLDSLLKQQEAVPKIPQPKRQSTMVNSSNYLDRGILK 246
Query: 236 LQNKSDDLPHWVLSAMKCLANWP 258
+ S + W+ +A+ CL P
Sbjct: 247 AYSDSQE-DEWLSAAIDCLEYLP 268
>gi|22748695 DEP domain containing 4 [Homo sapiens]
Length = 294
Score = 62.0 bits (149), Expect = 2e-09
Identities = 50/218 (22%), Positives = 97/218 (44%), Gaps = 27/218 (12%)
Query: 9 GPYRATKLWNEVTTSFRAGMPLRKHRQHFKKYGNCFTAGEAVD-WLYDLLRNNSNFGPEV 67
GP++AT+LW+ + S +A + +++ R H + Y +CFT +AVD L L++N ++
Sbjct: 56 GPFQATQLWDGIIHSLQAQVEIKRRRHHLQTYKDCFTGSDAVDVVLSHLMQNTCLSSNDI 115
Query: 68 TRQQTIQLLRKFLKNHVIEDI------KGRWGSENVDDNNQLFRFPATSPLKTLPRRYPE 121
+ + + L + + + V E + K E D N L+RF
Sbjct: 116 SCLKGVHLCQVLMNHKVFEPVGMKKLFKKEKELEFEDSNISLYRFLG------------- 162
Query: 122 LRKNNIENFSKDKDSIFKLRNLSRRTPKRHGLHLSQENGEKIKHEIINEDQ------ENA 175
K++ + + KD+ + R + L+QE GE+ E+I+ N
Sbjct: 163 -NKSSYDCCKRQKDAENEFNETLRPGYEMISNPLAQEIGEERIEELIHTINGNPALCPNI 221
Query: 176 IDNRELSQEDVEEVWRYVILIYLQTILGVPSLEEVINP 213
+ + E+VW+ L+ L ++ +P L+ ++ P
Sbjct: 222 TVQKPFLRLSKEDVWKEQTLLCLLQLIHLPFLDNILEP 259
>gi|67906814 Rho GTPase activating protein 19 [Homo sapiens]
Length = 494
Score = 49.7 bits (117), Expect = 1e-05
Identities = 48/194 (24%), Positives = 93/194 (47%), Gaps = 17/194 (8%)
Query: 599 IDALQLCCLLLPPPNRRKLQLLMRMISRMSQNVDMPKLHDAMGTRSLMIHT-FSRCVLCC 657
I+ALQL L+LPPPNR L+LL+ ++ + ++ D K+ H + + V
Sbjct: 225 IEALQLLFLILPPPNRNLLKLLLDLLYQTAKKQDKNKMSAYNLALMFAPHVLWPKNVTAN 284
Query: 658 AEEVDLDELLAGRLVSFLMDHHQEILQVPSYLQTAVEKHLDYLKKGHIENPGD-GLFAPL 716
+ ++ +L +G ++F++ H Q++ + P+Y++ H YL + D L A
Sbjct: 285 DLQENITKLNSG--MAFMIKHSQKLFKAPAYIRECARLH--YLGSRTQASKDDLDLIASC 340
Query: 717 PTYSY-------CKQISAQEFDEQKVSTSQAAIAELLENIIKNRSLPLKEKRKKL-KQFQ 768
T S+ ++ + E+ ++ A+ EL +++ +P K+K+L +QF
Sbjct: 341 HTKSFQLAKSQKRNRVDSCPHQEETQHHTEEALRELFQHV---HDMPESAKKKQLIRQFN 397
Query: 769 KEYPLIYQKRFPTT 782
K+ R P+T
Sbjct: 398 KQSLTQTPGREPST 411
>gi|41281907 StAR-related lipid transfer (START) domain containing
13 isoform beta [Homo sapiens]
Length = 1105
Score = 36.2 bits (82), Expect = 0.13
Identities = 30/108 (27%), Positives = 47/108 (43%), Gaps = 11/108 (10%)
Query: 199 QTILGVPSLEEVINPKQVIPQYIMYNMANTSKRGVVILQNKSDDLPHWVLSAMKCLANWP 258
+ + GVP + V Q +PQ I + + N D + + S +K +
Sbjct: 650 KAVFGVPLIVHVQRTGQPLPQSIQQALR-------YLRSNCLDQVGLFRKSGVKSRIHAL 702
Query: 259 RSNDMNNPTYVGFER----DVFRTIADYFLDLPEPLLTFEYYELFVNI 302
R + N P V +E DV + +F DLPEPL T + E F++I
Sbjct: 703 RQMNENFPENVNYEDQSAYDVADMVKQFFRDLPEPLFTNKLSETFLHI 750
>gi|16445031 StAR-related lipid transfer (START) domain containing
13 isoform gamma [Homo sapiens]
Length = 995
Score = 36.2 bits (82), Expect = 0.13
Identities = 30/108 (27%), Positives = 47/108 (43%), Gaps = 11/108 (10%)
Query: 199 QTILGVPSLEEVINPKQVIPQYIMYNMANTSKRGVVILQNKSDDLPHWVLSAMKCLANWP 258
+ + GVP + V Q +PQ I + + N D + + S +K +
Sbjct: 540 KAVFGVPLIVHVQRTGQPLPQSIQQALR-------YLRSNCLDQVGLFRKSGVKSRIHAL 592
Query: 259 RSNDMNNPTYVGFER----DVFRTIADYFLDLPEPLLTFEYYELFVNI 302
R + N P V +E DV + +F DLPEPL T + E F++I
Sbjct: 593 RQMNENFPENVNYEDQSAYDVADMVKQFFRDLPEPLFTNKLSETFLHI 640
>gi|41281898 StAR-related lipid transfer (START) domain containing
13 isoform alpha [Homo sapiens]
Length = 1113
Score = 36.2 bits (82), Expect = 0.13
Identities = 30/108 (27%), Positives = 47/108 (43%), Gaps = 11/108 (10%)
Query: 199 QTILGVPSLEEVINPKQVIPQYIMYNMANTSKRGVVILQNKSDDLPHWVLSAMKCLANWP 258
+ + GVP + V Q +PQ I + + N D + + S +K +
Sbjct: 658 KAVFGVPLIVHVQRTGQPLPQSIQQALR-------YLRSNCLDQVGLFRKSGVKSRIHAL 710
Query: 259 RSNDMNNPTYVGFER----DVFRTIADYFLDLPEPLLTFEYYELFVNI 302
R + N P V +E DV + +F DLPEPL T + E F++I
Sbjct: 711 RQMNENFPENVNYEDQSAYDVADMVKQFFRDLPEPLFTNKLSETFLHI 758
>gi|189571664 DEP domain containing 6 [Homo sapiens]
Length = 409
Score = 35.8 bits (81), Expect = 0.16
Identities = 17/59 (28%), Positives = 28/59 (47%), Gaps = 7/59 (11%)
Query: 30 LRKHRQHFKKYGNCFTAGEAVDWLYDLLRNNSNFGPEVTRQQTIQLLRKFLKNHVIEDI 88
++ R H K Y NCF A E +DWL + + R+ I+L++K +I +
Sbjct: 50 IKDRRHHLKTYPNCFVAKELIDWLIEHKEASD-------RETAIKLMQKLADRGIIHHV 101
>gi|170763479 MMS19 nucleotide excision repair homolog [Homo
sapiens]
Length = 1030
Score = 35.0 bits (79), Expect = 0.28
Identities = 23/82 (28%), Positives = 39/82 (47%), Gaps = 9/82 (10%)
Query: 614 RRKLQLLMRMISRMSQNVDMPKLHDAMGTRSLMIHTFSRCVLCCAEEVDLDELLAGRLVS 673
RR + LLM + + +NV++P+L+ M R L+ L C A + +
Sbjct: 712 RRLIALLMAFVCSLPRNVEIPQLNQLM--RELL-------ELSCCHSCPFSSTAAAKCFA 762
Query: 674 FLMDHHQEILQVPSYLQTAVEK 695
L++ H Q+ +LQ AV+K
Sbjct: 763 GLLNKHPAGQQLDEFLQLAVDK 784
>gi|120953300 leucine-rich repeats and IQ motif containing 1 isoform
1 [Homo sapiens]
Length = 1722
Score = 35.0 bits (79), Expect = 0.28
Identities = 35/184 (19%), Positives = 73/184 (39%), Gaps = 7/184 (3%)
Query: 18 NEVTTSFRAGMPLRKHRQHFKKYGNCFTAGEAVDWLYDLLRNNSNFGPEVTRQQTIQLLR 77
NE R L K + ++ N G + DL N P + Q
Sbjct: 484 NENLAKKRCSEELVKQERKYENTDNKTELGNS-----DLKGNLKEQFPLQELKSDAQKEE 538
Query: 78 KFLKNHVIEDIKGRWGSENVDDNNQLFRFPATSPLKTLP-RRYPELRKNNIENFSKDKDS 136
K +K HVI + G+ + N ++ K + + +++K E +
Sbjct: 539 KIMK-HVINENTGQKTQIILGHNQEISEVKTNEEQKIIKDNQQKKIQKVEKEEIQEQNGL 597
Query: 137 IFKLRNLSRRTPKRHGLHLSQENGEKIKHEIINEDQENAIDNRELSQEDVEEVWRYVILI 196
++K ++ + K+ L L+ EN + ++ +I +++E ++E+ + + W I+I
Sbjct: 598 LYKDKDTLVISVKQRSLSLTSENSKDVRENVILQEKEIYSKSKEIEENPKDNAWNSGIVI 657
Query: 197 YLQT 200
+ T
Sbjct: 658 FNTT 661
>gi|120953243 leucine-rich repeats and IQ motif containing 1 isoform
2 [Homo sapiens]
Length = 1336
Score = 35.0 bits (79), Expect = 0.28
Identities = 35/184 (19%), Positives = 73/184 (39%), Gaps = 7/184 (3%)
Query: 18 NEVTTSFRAGMPLRKHRQHFKKYGNCFTAGEAVDWLYDLLRNNSNFGPEVTRQQTIQLLR 77
NE R L K + ++ N G + DL N P + Q
Sbjct: 484 NENLAKKRCSEELVKQERKYENTDNKTELGNS-----DLKGNLKEQFPLQELKSDAQKEE 538
Query: 78 KFLKNHVIEDIKGRWGSENVDDNNQLFRFPATSPLKTLP-RRYPELRKNNIENFSKDKDS 136
K +K HVI + G+ + N ++ K + + +++K E +
Sbjct: 539 KIMK-HVINENTGQKTQIILGHNQEISEVKTNEEQKIIKDNQQKKIQKVEKEEIQEQNGL 597
Query: 137 IFKLRNLSRRTPKRHGLHLSQENGEKIKHEIINEDQENAIDNRELSQEDVEEVWRYVILI 196
++K ++ + K+ L L+ EN + ++ +I +++E ++E+ + + W I+I
Sbjct: 598 LYKDKDTLVISVKQRSLSLTSENSKDVRENVILQEKEIYSKSKEIEENPKDNAWNSGIVI 657
Query: 197 YLQT 200
+ T
Sbjct: 658 FNTT 661
>gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III
isoform 2 [Homo sapiens]
Length = 2098
Score = 34.3 bits (77), Expect = 0.48
Identities = 27/90 (30%), Positives = 41/90 (45%), Gaps = 17/90 (18%)
Query: 16 LWNEVTTSFRAGMPLRKHRQHFKKYGNCFTAGEAVDWLYDLLRNNSNFGPEVTRQQTIQL 75
LW ++ +GM + HR + + NC E V+W L+RN G TR Q I +
Sbjct: 358 LWKKIC-HHSSGMEFQDHRYWLRTHPNCIVGKELVNW---LIRN----GHIATRAQAIAI 409
Query: 76 LRKFLKNHVIEDIKGRWGSENVDDNNQLFR 105
+ + GRW + V ++QLFR
Sbjct: 410 GQAM--------VDGRW-LDCVSHHDQLFR 430
>gi|22749359 phosphatidylinositol-3-phosphate 5-kinase type III
isoform 3 [Homo sapiens]
Length = 451
Score = 34.3 bits (77), Expect = 0.48
Identities = 27/90 (30%), Positives = 41/90 (45%), Gaps = 17/90 (18%)
Query: 16 LWNEVTTSFRAGMPLRKHRQHFKKYGNCFTAGEAVDWLYDLLRNNSNFGPEVTRQQTIQL 75
LW ++ +GM + HR + + NC E V+W L+RN G TR Q I +
Sbjct: 261 LWKKIC-HHSSGMEFQDHRYWLRTHPNCIVGKELVNW---LIRN----GHIATRAQAIAI 312
Query: 76 LRKFLKNHVIEDIKGRWGSENVDDNNQLFR 105
+ + GRW + V ++QLFR
Sbjct: 313 GQAM--------VDGRW-LDCVSHHDQLFR 333
>gi|7657039 tumor necrosis factor receptor superfamily, member 21
precursor [Homo sapiens]
Length = 655
Score = 33.5 bits (75), Expect = 0.81
Identities = 28/104 (26%), Positives = 47/104 (45%), Gaps = 7/104 (6%)
Query: 40 YGNCFTAGEAVDWLYDLLRNNSNFGPEVTRQQTIQLLRKFLKNHVIEDIKGRWGSENVDD 99
+ N +TA + Y L++ + GPE + Q I LR+ +N V+E I+G +
Sbjct: 448 FSNGYTADH--ERAYAALQHWTIRGPEASLAQLISALRQHRRNDVVEKIRGLMEDTTQLE 505
Query: 100 NNQLFRFPATSPLKTLPRRYPELRKNN-----IENFSKDKDSIF 138
++L + SPL P P + N +E +DK+ F
Sbjct: 506 TDKLALPMSPSPLSPSPIPSPNAKLENSALLTVEPSPQDKNKGF 549
>gi|194306650 SET domain and mariner transposase fusion [Homo
sapiens]
Length = 684
Score = 33.1 bits (74), Expect = 1.1
Identities = 29/101 (28%), Positives = 45/101 (44%), Gaps = 4/101 (3%)
Query: 60 NSNFGPEVTRQQTIQL-LRKFLKNHVIEDIKGRWGSENVDDNNQLFRFPATSPLKTLPRR 118
N+ FGP ++T+Q +KF K + + R G + DN+QL PL T
Sbjct: 373 NNAFGPGTANERTVQWWFKKFCKGDESLEDEERSGRPSEVDNDQLRAIIEADPLTTTREV 432
Query: 119 YPELRKNNIENFSKDKDSIFKLRNLSRRTPKRHGLHLSQEN 159
EL N+ + I K++ L + P H L +Q+N
Sbjct: 433 AEELNVNH-STVVRHLKQIGKVKKLDKWVP--HELTENQKN 470
>gi|59710113 Rho GTPase activating protein 28 isoform a [Homo
sapiens]
Length = 570
Score = 33.1 bits (74), Expect = 1.1
Identities = 29/110 (26%), Positives = 52/110 (47%), Gaps = 13/110 (11%)
Query: 592 PHLERVAIDALQLCCLLLPPPNRRKLQLLMRMISRMSQNVDMPKLHDAMGTRSLMIHT-- 649
PH+ +V AL L + LP NR Q LM +++ N ++ ++M
Sbjct: 328 PHV-KVQFQALHLMVMALPDANRDAAQALMTFFNKVIANESKNRM-SLWNISTVMAPNLF 385
Query: 650 FSRCVLCCAEEVDLDELL----AGRLVSFLMDHHQEILQVPSYLQTAVEK 695
FSR ++ D +ELL A ++ ++ + + + +VPS+L T V +
Sbjct: 386 FSR-----SKHSDYEELLLANTAAHIIRLMLKYQKILWKVPSFLITQVRR 430
>gi|59710111 Rho GTPase activating protein 28 isoform b [Homo
sapiens]
Length = 563
Score = 33.1 bits (74), Expect = 1.1
Identities = 29/110 (26%), Positives = 52/110 (47%), Gaps = 13/110 (11%)
Query: 592 PHLERVAIDALQLCCLLLPPPNRRKLQLLMRMISRMSQNVDMPKLHDAMGTRSLMIHT-- 649
PH+ +V AL L + LP NR Q LM +++ N ++ ++M
Sbjct: 328 PHV-KVQFQALHLMVMALPDANRDAAQALMTFFNKVIANESKNRM-SLWNISTVMAPNLF 385
Query: 650 FSRCVLCCAEEVDLDELL----AGRLVSFLMDHHQEILQVPSYLQTAVEK 695
FSR ++ D +ELL A ++ ++ + + + +VPS+L T V +
Sbjct: 386 FSR-----SKHSDYEELLLANTAAHIIRLMLKYQKILWKVPSFLITQVRR 430
>gi|215820652 StAR-related lipid transfer (START) domain containing
8 isoform b [Homo sapiens]
Length = 1023
Score = 32.7 bits (73), Expect = 1.4
Identities = 44/193 (22%), Positives = 75/193 (38%), Gaps = 27/193 (13%)
Query: 199 QTILGVPSLEEVINPKQVIPQYIMYNMANTSKRGVVILQNKSDDLPHWVLSAMKCLANWP 258
Q + GVP L V Q +PQ I M + + D + + S +K
Sbjct: 567 QHVFGVPPLIHVQRTGQPLPQSIQQAMRYLRSQCL-------DQVGIFRKSGVKSRIQNL 619
Query: 259 RSNDMNNPTYVGFERDVFRTIAD----YFLDLPEPLLTFEYYELFVNI---LVVCGYITV 311
R + +P V +E +AD YF DLPEP+ T + F+ I L ++
Sbjct: 620 RQMNETSPDNVCYEGQSAYDVADLLKQYFRDLPEPIFTSKLTTTFLQIYQLLPKDQWLAA 679
Query: 312 SDRSSGIHKIQDDPQSSKFLHL---------NNLNSFKSTECLLLSLLHREKNKEESDS- 361
+ ++ + ++ L+ N + + CL S+ H +K++S S
Sbjct: 680 AQAATLLLPDENREVLQTLLYFLSDIASAEENQMTAGNLAVCLAPSIFHLNVSKKDSPSP 739
Query: 362 ---TERLQISNPG 371
++R I PG
Sbjct: 740 RIKSKRSLIGRPG 752
>gi|215820650 StAR-related lipid transfer (START) domain containing
8 isoform a [Homo sapiens]
Length = 1103
Score = 32.7 bits (73), Expect = 1.4
Identities = 44/193 (22%), Positives = 75/193 (38%), Gaps = 27/193 (13%)
Query: 199 QTILGVPSLEEVINPKQVIPQYIMYNMANTSKRGVVILQNKSDDLPHWVLSAMKCLANWP 258
Q + GVP L V Q +PQ I M + + D + + S +K
Sbjct: 647 QHVFGVPPLIHVQRTGQPLPQSIQQAMRYLRSQCL-------DQVGIFRKSGVKSRIQNL 699
Query: 259 RSNDMNNPTYVGFERDVFRTIAD----YFLDLPEPLLTFEYYELFVNI---LVVCGYITV 311
R + +P V +E +AD YF DLPEP+ T + F+ I L ++
Sbjct: 700 RQMNETSPDNVCYEGQSAYDVADLLKQYFRDLPEPIFTSKLTTTFLQIYQLLPKDQWLAA 759
Query: 312 SDRSSGIHKIQDDPQSSKFLHL---------NNLNSFKSTECLLLSLLHREKNKEESDS- 361
+ ++ + ++ L+ N + + CL S+ H +K++S S
Sbjct: 760 AQAATLLLPDENREVLQTLLYFLSDIASAEENQMTAGNLAVCLAPSIFHLNVSKKDSPSP 819
Query: 362 ---TERLQISNPG 371
++R I PG
Sbjct: 820 RIKSKRSLIGRPG 832
>gi|31543659 StAR-related lipid transfer (START) domain containing 8
isoform b [Homo sapiens]
Length = 1023
Score = 32.7 bits (73), Expect = 1.4
Identities = 44/193 (22%), Positives = 75/193 (38%), Gaps = 27/193 (13%)
Query: 199 QTILGVPSLEEVINPKQVIPQYIMYNMANTSKRGVVILQNKSDDLPHWVLSAMKCLANWP 258
Q + GVP L V Q +PQ I M + + D + + S +K
Sbjct: 567 QHVFGVPPLIHVQRTGQPLPQSIQQAMRYLRSQCL-------DQVGIFRKSGVKSRIQNL 619
Query: 259 RSNDMNNPTYVGFERDVFRTIAD----YFLDLPEPLLTFEYYELFVNI---LVVCGYITV 311
R + +P V +E +AD YF DLPEP+ T + F+ I L ++
Sbjct: 620 RQMNETSPDNVCYEGQSAYDVADLLKQYFRDLPEPIFTSKLTTTFLQIYQLLPKDQWLAA 679
Query: 312 SDRSSGIHKIQDDPQSSKFLHL---------NNLNSFKSTECLLLSLLHREKNKEESDS- 361
+ ++ + ++ L+ N + + CL S+ H +K++S S
Sbjct: 680 AQAATLLLPDENREVLQTLLYFLSDIASAEENQMTAGNLAVCLAPSIFHLNVSKKDSPSP 739
Query: 362 ---TERLQISNPG 371
++R I PG
Sbjct: 740 RIKSKRSLIGRPG 752
>gi|7382480 Rho GTPase activating protein 6 isoform 4 [Homo sapiens]
Length = 771
Score = 32.7 bits (73), Expect = 1.4
Identities = 13/32 (40%), Positives = 21/32 (65%)
Query: 274 DVFRTIADYFLDLPEPLLTFEYYELFVNILVV 305
DV + ++ D+P+PLLT E Y F+N L++
Sbjct: 261 DVAALLKEFLRDMPDPLLTRELYTAFINTLLL 292
>gi|95091988 Rho GTPase activating protein 6 isoform 3 [Homo
sapiens]
Length = 765
Score = 32.7 bits (73), Expect = 1.4
Identities = 13/32 (40%), Positives = 21/32 (65%)
Query: 274 DVFRTIADYFLDLPEPLLTFEYYELFVNILVV 305
DV + ++ D+P+PLLT E Y F+N L++
Sbjct: 464 DVAALLKEFLRDMPDPLLTRELYTAFINTLLL 495
>gi|95091875 Rho GTPase activating protein 6 isoform 1 [Homo
sapiens]
Length = 974
Score = 32.7 bits (73), Expect = 1.4
Identities = 13/32 (40%), Positives = 21/32 (65%)
Query: 274 DVFRTIADYFLDLPEPLLTFEYYELFVNILVV 305
DV + ++ D+P+PLLT E Y F+N L++
Sbjct: 464 DVAALLKEFLRDMPDPLLTRELYTAFINTLLL 495
>gi|195972871 phospholipase C eta 1 isoform a [Homo sapiens]
Length = 1693
Score = 32.3 bits (72), Expect = 1.8
Identities = 30/94 (31%), Positives = 38/94 (40%), Gaps = 10/94 (10%)
Query: 498 CNGKCKSKQLCRSQSLLLRSSTRRNSYINTPVAEII------MKPNVGQGSTSVQTAMES 551
C GK KS LC S L+ SS+ + V E KP+ S + A+ES
Sbjct: 1243 CKGKSKSSFLCSSPELIALSSSETTKHATNTVYETTCTPISKTKPDDDLSSKAKTAALES 1302
Query: 552 ELGESSATINKRLCKSTIELSE----NSLLPASS 581
L S T L KS + + S PASS
Sbjct: 1303 NLPGSPNTSRGWLPKSPTKGEDWETLKSCSPASS 1336
>gi|57863298 phospholipase C eta 1 isoform b [Homo sapiens]
Length = 1655
Score = 32.3 bits (72), Expect = 1.8
Identities = 30/94 (31%), Positives = 38/94 (40%), Gaps = 10/94 (10%)
Query: 498 CNGKCKSKQLCRSQSLLLRSSTRRNSYINTPVAEII------MKPNVGQGSTSVQTAMES 551
C GK KS LC S L+ SS+ + V E KP+ S + A+ES
Sbjct: 1205 CKGKSKSSFLCSSPELIALSSSETTKHATNTVYETTCTPISKTKPDDDLSSKAKTAALES 1264
Query: 552 ELGESSATINKRLCKSTIELSE----NSLLPASS 581
L S T L KS + + S PASS
Sbjct: 1265 NLPGSPNTSRGWLPKSPTKGEDWETLKSCSPASS 1298
>gi|27262630 nuclear autoantigenic sperm protein isoform 3 [Homo
sapiens]
Length = 449
Score = 32.3 bits (72), Expect = 1.8
Identities = 16/37 (43%), Positives = 25/37 (67%), Gaps = 1/37 (2%)
Query: 152 GLHLSQENGEKIKHEIINEDQENAIDNRELSQEDVEE 188
G+H+ +E GEK + E + E+ +N ID E S+ED +E
Sbjct: 112 GVHVEEEEGEKTEDESLVENNDN-IDETEGSEEDDKE 147
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.388
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,859,582
Number of Sequences: 37866
Number of extensions: 1372425
Number of successful extensions: 4126
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 40
Number of HSP's that attempted gapping in prelim test: 4051
Number of HSP's gapped (non-prelim): 104
length of query: 811
length of database: 18,247,518
effective HSP length: 111
effective length of query: 700
effective length of database: 14,044,392
effective search space: 9831074400
effective search space used: 9831074400
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.