Guide to the Human Genome
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Name: SETMAR Sequence: fasta or formatted (684aa) NCBI GI: 194306650
Description:

SET domain and mariner transposase fusion

Referenced in:

Histones, Related Proteins, and Modifying Enzymes
DNA Transposon and Retrovirus-related Sequences

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.7         39           2
 C cysteine            3.7         25           1
 D aspartate           5.0         34           2
 E glutamate           7.7         53           3
 F phenylalanine       5.0         34           1
 G glycine             5.7         39           2
 H histidine           3.2         22           1
 I isoleucine          4.7         32           2
 K lysine              6.7         46           2
 L leucine             8.3         57           2
 M methionine          1.8         12           2
 N asparagine          5.4         37           2
 P proline             6.6         45           2
 Q glutamine           4.4         30           2
 R arginine            5.6         38           3
 S serine              5.4         37           3
 T threonine           5.0         34           3
 V valine              5.8         40           2
 W tryptophan          1.5         10           2
 Y tyrosine            2.9         20           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   SET domain and mariner transposase fusion 
EHMT1                 0.082   euchromatic histone-lysine N-methyltransferase 1 is...
SUV39H1               0.081   suppressor of variegation 3-9 homolog 1 
EHMT2                 0.081   euchromatic histone-lysine N-methyltransferase 2 is...
EHMT2                 0.081   euchromatic histone-lysine N-methyltransferase 2 is...
SUV39H2               0.074   suppressor of variegation 3-9 homolog 2 
SETD2                 0.053   SET domain containing 2 
WHSC1L1               0.047   WHSC1L1 protein isoform long 
ASH1L                 0.045   absent, small, or homeotic 1-like 
NSD1                  0.043   nuclear receptor binding SET domain protein 1 isofor...
NSD1                  0.043   nuclear receptor binding SET domain protein 1 isofor...
SETDB1                0.042   SET domain, bifurcated 1 isoform 2 
SETDB1                0.042   SET domain, bifurcated 1 isoform 1 
WHSC1                 0.041   Wolf-Hirschhorn syndrome candidate 1 protein isoform...
WHSC1                 0.041   Wolf-Hirschhorn syndrome candidate 1 protein isoform...
WHSC1                 0.041   Wolf-Hirschhorn syndrome candidate 1 protein isoform...
WHSC1                 0.041   Wolf-Hirschhorn syndrome candidate 1 protein isofor...
EZH1                  0.040   enhancer of zeste homolog 1 
SETDB2                0.035   SET domain, bifurcated 2 isoform b 
SETDB2                0.035   SET domain, bifurcated 2 isoform a 
EZH2                  0.034   enhancer of zeste 2 isoform b 
EZH2                  0.034   enhancer of zeste 2 isoform a 
MLL                   0.034   myeloid/lymphoid or mixed-lineage leukemia protein [...
SETD1A                0.031   SET domain containing 1A 
SETD1B                0.029   SET domain containing 1B 
MLL4                  0.028   myeloid/lymphoid or mixed-lineage leukemia 4 
MLL2                  0.023   myeloid/lymphoid or mixed-lineage leukemia 2 
MLL3                  0.020   myeloid/lymphoid or mixed-lineage leukemia 3 
SETD8                 0.018   SET domain-containing 8 
SETD5                 0.013   SET domain containing 5 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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