Guide to the Human Genome
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Name: PIKFYVE Sequence: fasta or formatted (451aa) NCBI GI: 22749359
Description:

phosphatidylinositol-3-phosphate 5-kinase type III isoform 3

Referenced in:

Inositol Pathways
Zinc Finger Proteins

Other entries for this name:
alt prot [2098aa] phosphatidylinositol-3-phosphate 5-kinase type III isoform 2
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.2         28           2
 C cysteine            1.3          6           1
 D aspartate           8.0         36           2
 E glutamate           5.5         25           2
 F phenylalanine       2.9         13           1
 G glycine             3.8         17           2
 H histidine           3.3         15           2
 I isoleucine          3.5         16           1
 K lysine              4.7         21           2
 L leucine             8.0         36           2
 M methionine          0.9          4           1
 N asparagine          4.4         20           1
 P proline             7.3         33           2
 Q glutamine           4.4         20           2
 R arginine            6.4         29           2
 S serine             14.6         66           2
 T threonine           6.0         27           2
 V valine              4.9         22           1
 W tryptophan          1.6          7           1
 Y tyrosine            2.2         10           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   phosphatidylinositol-3-phosphate 5-kinase type III i... 
PIKFYVE               0.750   phosphatidylinositol-3-phosphate 5-kinase type III ...
DEPDC6                0.028   DEP domain containing 6 
RAPGEF4               0.026   Rap guanine nucleotide exchange factor (GEF) 4 isof...
RAPGEF4               0.026   Rap guanine nucleotide exchange factor (GEF) 4 isof...
PREX2                 0.026   DEP domain containing 2 isoform b 
PREX2                 0.026   DEP domain containing 2 isoform a 
PREX1                 0.024   phosphatidylinositol-3,4,5-trisphosphate-dependent R...
GPR155                0.024   G protein-coupled receptor 155 isoform 9 
GPR155                0.024   G protein-coupled receptor 155 isoform 10 
RGS7                  0.016   regulator of G-protein signaling 7 
MUC12                 0.013   PREDICTED: mucin 12 
MUC12                 0.012   PREDICTED: mucin 12, cell surface associated 
RGS6                  0.012   regulator of G-protein signalling 6 
DEPDC5                0.011   DEP domain containing 5 isoform 3 
DEPDC7                0.011   novel 58.3 KDA protein isoform 2 
DEPDC7                0.011   novel 58.3 KDA protein isoform 1 
DEPDC5                0.011   DEP domain containing 5 isoform 1 
DVL3                  0.011   dishevelled 3 
ACRC                  0.011   ACRC protein 
PPP1R12C              0.011   protein phosphatase 1, regulatory subunit 12C 
DEPDC1                0.010   DEP domain containing 1 isoform a 
DEPDC1                0.010   DEP domain containing 1 isoform b 
LY6K                  0.010   lymphocyte antigen 6 complex, locus K isoform 3 [Ho...
ANKRD11               0.010   ankyrin repeat domain 11 
MKNK1                 0.009   MAP kinase-interacting serine/threonine kinase 1 is...
MKNK1                 0.009   MAP kinase-interacting serine/threonine kinase 1 iso...
LOC100134663          0.009   PREDICTED: hypothetical protein, partial 
DSPP                  0.009   dentin sialophosphoprotein preproprotein 
TRIO                  0.009   triple functional domain (PTPRF interacting) 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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