GEFT 5058

Name: GEFT	Sequence: fasta or formatted (580aa)		NCBI GI: 150417975
Description: RhoA/RAC/CDC42 exchange factor isoform 1		Referenced in: Rho and Rac
Other entries for this name: alt prot [619aa] RhoA/RAC/CDC42 exchange factor isoform 3
Composition: Amino acid Percentage Count Longest homopolymer A alanine 6.7 39 2 C cysteine 2.4 14 2 D aspartate 4.3 25 2 E glutamate 7.9 46 3 F phenylalanine 2.6 15 1 G glycine 10.2 59 3 H histidine 1.9 11 1 I isoleucine 3.8 22 3 K lysine 4.7 27 3 L leucine 11.6 67 3 M methionine 2.1 12 2 N asparagine 1.9 11 1 P proline 7.1 41 2 Q glutamine 6.2 36 2 R arginine 6.9 40 2 S serine 7.4 43 2 T threonine 3.6 21 2 V valine 4.8 28 2 W tryptophan 1.0 6 1 Y tyrosine 2.9 17 2			Comparative genomics: Search single species RefSeq proteins at NCBI H. sapiens M. musculus D. rerio C. intestinalis S. purpuratus D. melanogaster C. elegans A. thaliana S. cerevisiae E. coli W3110 A. pernix K1 Search summary Figure data Additional searches of RefSeq proteins at NCBI All Eukaryotes Bacteria Archaea Viruses Primates Mammals Vertebrates
Related human proteins: Protein Relative score Description Self-match 1.000 RhoA/RAC/CDC42 exchange factor isoform 1 GEFT 0.938 RhoA/RAC/CDC42 exchange factor isoform 3 TRIO 0.377 triple functional domain (PTPRF interacting) KALRN 0.351 kalirin, RhoGEF kinase isoform 1 KALRN 0.351 kalirin, RhoGEF kinase isoform 3 KALRN 0.178 kalirin, RhoGEF kinase isoform 2 PLEKHG4B 0.149 pleckstrin homology domain containing, family G (wi... MCF2L 0.145 MCF.2 cell line derived transforming sequence-like ... MCF2L 0.145 MCF.2 cell line derived transforming sequence-like ... MCF2 0.138 MCF.2 cell line derived transforming sequence isofo... MCF2 0.138 MCF.2 cell line derived transforming sequence isofo... PLEKHG4 0.130 pleckstrin homology domain containing, family G (wi... PLEKHG4 0.130 pleckstrin homology domain containing, family G (wi... PLEKHG4 0.130 pleckstrin homology domain containing, family G (wi... PLEKHG4 0.130 pleckstrin homology domain containing, family G (wi... PLEKHG4 0.130 pleckstrin homology domain containing, family G (wit... MCF2L2 0.113 Rho family guanine-nucleotide exchange factor OBSCN 0.087 obscurin, cytoskeletal calmodulin and titin-interact... OBSCN 0.087 obscurin, cytoskeletal calmodulin and titin-interac... PLEKHG1 0.076 pleckstrin homology domain containing, family G (wit... FLJ10357 0.076 hypothetical protein LOC55701 PLEKHG2 0.068 common-site lymphoma/leukemia guanine nucleotide ex... FGD3 0.051 FYVE, RhoGEF and PH domain containing 3 FGD3 0.051 FYVE, RhoGEF and PH domain containing 3 VAV1 0.045 vav 1 guanine nucleotide exchange factor ARHGEF4 0.045 Rho guanine nucleotide exchange factor 4 isoform b [... FGD2 0.044 FYVE, RhoGEF and PH domain containing 2 ARHGEF4 0.043 Rho guanine nucleotide exchange factor 4 isoform a [... FARP2 0.042 FERM, RhoGEF and pleckstrin domain protein 2 FGD1 0.041 faciogenital dysplasia protein Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.