Guide to the Human Genome
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Name: MCF2L2 Sequence: fasta or formatted (1114aa) NCBI GI: 31742505
Description:

Rho family guanine-nucleotide exchange factor

Referenced in:

Rho and Rac

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.2         69           2
 C cysteine            2.0         22           1
 D aspartate           5.4         60           2
 E glutamate           9.5        106           3
 F phenylalanine       4.5         50           1
 G glycine             5.4         60           2
 H histidine           2.9         32           2
 I isoleucine          5.8         65           2
 K lysine              7.4         82           3
 L leucine            11.3        126           3
 M methionine          2.2         24           1
 N asparagine          2.7         30           2
 P proline             4.2         47           2
 Q glutamine           5.6         62           2
 R arginine            5.8         65           3
 S serine              7.5         84           2
 T threonine           5.2         58           2
 V valine              3.5         39           2
 W tryptophan          1.0         11           1
 Y tyrosine            2.0         22           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   Rho family guanine-nucleotide exchange factor 
MCF2L                 0.363   MCF.2 cell line derived transforming sequence-like ...
MCF2L                 0.363   MCF.2 cell line derived transforming sequence-like ...
MCF2                  0.275   MCF.2 cell line derived transforming sequence isofo...
MCF2                  0.244   MCF.2 cell line derived transforming sequence isofo...
TRIO                  0.071   triple functional domain (PTPRF interacting) 
KALRN                 0.066   kalirin, RhoGEF kinase isoform 1 
KALRN                 0.066   kalirin, RhoGEF kinase isoform 2 
GEFT                  0.059   RhoA/RAC/CDC42 exchange factor isoform 1 
GEFT                  0.059   RhoA/RAC/CDC42 exchange factor isoform 3 
KALRN                 0.054   kalirin, RhoGEF kinase isoform 3 
PLEKHG4               0.047   pleckstrin homology domain containing, family G (wi...
PLEKHG4               0.047   pleckstrin homology domain containing, family G (wi...
PLEKHG4               0.047   pleckstrin homology domain containing, family G (wi...
PLEKHG4               0.047   pleckstrin homology domain containing, family G (wit...
PLEKHG4               0.046   pleckstrin homology domain containing, family G (wi...
PLEKHG4B              0.043   pleckstrin homology domain containing, family G (wi...
PLEKHG1               0.038   pleckstrin homology domain containing, family G (wit...
OBSCN                 0.031   obscurin, cytoskeletal calmodulin and titin-interact...
OBSCN                 0.031   obscurin, cytoskeletal calmodulin and titin-interac...
PLEKHG2               0.030   common-site lymphoma/leukemia guanine nucleotide ex...
SESTD1                0.028   SEC14 and spectrin domains 1 
FLJ10357              0.025   hypothetical protein LOC55701 
SPATA13               0.023   spermatogenesis associated 13 
PLEKHG3               0.020   pleckstrin homology domain containing, family G, mem...
TIAM1                 0.019   T-cell lymphoma invasion and metastasis 1 
ARHGEF4               0.017   Rho guanine nucleotide exchange factor 4 isoform a [...
ARHGEF4               0.017   Rho guanine nucleotide exchange factor 4 isoform b [...
PREX2                 0.016   DEP domain containing 2 isoform b 
PREX2                 0.016   DEP domain containing 2 isoform a 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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