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Search of human proteins with 164414437
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|164414437 netrin G1 isoform 2 [Homo sapiens]
(480 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|164414437 netrin G1 isoform 2 [Homo sapiens] 1022 0.0
gi|54312078 netrin G1 isoform 3 [Homo sapiens] 917 0.0
gi|164414431 netrin G1 isoform 1 [Homo sapiens] 834 0.0
gi|190014607 netrin G2 [Homo sapiens] 444 e-124
gi|148613884 netrin 1 [Homo sapiens] 173 4e-43
gi|110611156 laminin, gamma 3 precursor [Homo sapiens] 142 5e-34
gi|145309326 laminin, gamma 1 precursor [Homo sapiens] 140 3e-33
gi|21264602 laminin alpha 5 [Homo sapiens] 127 3e-29
gi|5453810 netrin 3 [Homo sapiens] 123 4e-28
gi|93204871 netrin 4 [Homo sapiens] 120 2e-27
gi|38788416 laminin, alpha 1 precursor [Homo sapiens] 116 4e-26
gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens] 116 5e-26
gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens] 116 5e-26
gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo s... 110 4e-24
gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sa... 110 4e-24
gi|143770880 laminin, beta 4 [Homo sapiens] 103 5e-22
gi|167614504 laminin, beta 1 precursor [Homo sapiens] 99 1e-20
gi|62868217 laminin, beta 3 precursor [Homo sapiens] 97 2e-20
gi|62868215 laminin, beta 3 precursor [Homo sapiens] 97 2e-20
gi|189083719 laminin, beta 3 precursor [Homo sapiens] 97 2e-20
gi|119703755 laminin, beta 2 precursor [Homo sapiens] 91 2e-18
gi|219842266 usherin isoform B [Homo sapiens] 65 1e-10
gi|219842259 usherin isoform A [Homo sapiens] 65 1e-10
gi|24308065 netrin 5 [Homo sapiens] 55 2e-07
gi|188528675 slit homolog 1 [Homo sapiens] 47 5e-05
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 44 4e-04
gi|122937283 6720455I24Rik homolog [Homo sapiens] 43 6e-04
gi|88702793 slit-like 2 [Homo sapiens] 43 7e-04
gi|148833508 notch1 preproprotein [Homo sapiens] 42 0.001
gi|55770876 notch4 preproprotein [Homo sapiens] 42 0.001
>gi|164414437 netrin G1 isoform 2 [Homo sapiens]
Length = 480
Score = 1022 bits (2642), Expect = 0.0
Identities = 480/480 (100%), Positives = 480/480 (100%)
Query: 1 MYLSRFLSIHALWVTVSSVMQPYPLVWGHYDLCKTQIYTEEGKVWDYMACQPESTDMTKY 60
MYLSRFLSIHALWVTVSSVMQPYPLVWGHYDLCKTQIYTEEGKVWDYMACQPESTDMTKY
Sbjct: 1 MYLSRFLSIHALWVTVSSVMQPYPLVWGHYDLCKTQIYTEEGKVWDYMACQPESTDMTKY 60
Query: 61 LKVKLDPPDITCGDPPETFCAMGNPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQS 120
LKVKLDPPDITCGDPPETFCAMGNPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQS
Sbjct: 61 LKVKLDPPDITCGDPPETFCAMGNPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQS 120
Query: 121 ATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYAT 180
ATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYAT
Sbjct: 121 ATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYAT 180
Query: 181 DCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNM 240
DCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNM
Sbjct: 181 DCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNM 240
Query: 241 ASLYGQLDTTKKLRDFFTVTDLRIRLLRPAVGEIFVDELHLARYFYAISDIKVRGRCKCN 300
ASLYGQLDTTKKLRDFFTVTDLRIRLLRPAVGEIFVDELHLARYFYAISDIKVRGRCKCN
Sbjct: 241 ASLYGQLDTTKKLRDFFTVTDLRIRLLRPAVGEIFVDELHLARYFYAISDIKVRGRCKCN 300
Query: 301 LHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISS 360
LHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISS
Sbjct: 301 LHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISS 360
Query: 361 IGNPPKFNRIWPNISSLEVSNPKQVAPKLALSTVSSVQVANHKRANVCDNELLHCQNGGT 420
IGNPPKFNRIWPNISSLEVSNPKQVAPKLALSTVSSVQVANHKRANVCDNELLHCQNGGT
Sbjct: 361 IGNPPKFNRIWPNISSLEVSNPKQVAPKLALSTVSSVQVANHKRANVCDNELLHCQNGGT 420
Query: 421 CHNNVRCLCPAAYTGILCEKLRCEEAGSCGSDSGQGAPPHGSPALLLLTTLLGTASPLVF 480
CHNNVRCLCPAAYTGILCEKLRCEEAGSCGSDSGQGAPPHGSPALLLLTTLLGTASPLVF
Sbjct: 421 CHNNVRCLCPAAYTGILCEKLRCEEAGSCGSDSGQGAPPHGSPALLLLTTLLGTASPLVF 480
>gi|54312078 netrin G1 isoform 3 [Homo sapiens]
Length = 438
Score = 917 bits (2369), Expect = 0.0
Identities = 437/480 (91%), Positives = 437/480 (91%), Gaps = 42/480 (8%)
Query: 1 MYLSRFLSIHALWVTVSSVMQPYPLVWGHYDLCKTQIYTEEGKVWDYMACQPESTDMTKY 60
MYLSRFLSIHALWVTVSSVMQPYPLVWGHYDLCKTQIYTEEGKVWDYMACQPESTDMTKY
Sbjct: 1 MYLSRFLSIHALWVTVSSVMQPYPLVWGHYDLCKTQIYTEEGKVWDYMACQPESTDMTKY 60
Query: 61 LKVKLDPPDITCGDPPETFCAMGNPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQS 120
LKVKLDPPDITCGDPPETFCAMGNPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQS
Sbjct: 61 LKVKLDPPDITCGDPPETFCAMGNPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQS 120
Query: 121 ATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYAT 180
ATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYAT
Sbjct: 121 ATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYAT 180
Query: 181 DCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNM 240
DCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNM
Sbjct: 181 DCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNM 240
Query: 241 ASLYGQLDTTKKLRDFFTVTDLRIRLLRPAVGEIFVDELHLARYFYAISDIKVRGRCKCN 300
ASLYGQLDTTKKLRDFFTVTDLRIRLLRPAVGEIFVDELHLARYFYAISDIKVRGRCKCN
Sbjct: 241 ASLYGQLDTTKKLRDFFTVTDLRIRLLRPAVGEIFVDELHLARYFYAISDIKVRGRCKCN 300
Query: 301 LHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISS 360
LHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISS
Sbjct: 301 LHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISS 360
Query: 361 IGNPPKFNRIWPNISSLEVSNPKQVAPKLALSTVSSVQVANHKRANVCDNELLHCQNGGT 420
IG NVCDNELLHCQNGGT
Sbjct: 361 IG------------------------------------------TNVCDNELLHCQNGGT 378
Query: 421 CHNNVRCLCPAAYTGILCEKLRCEEAGSCGSDSGQGAPPHGSPALLLLTTLLGTASPLVF 480
CHNNVRCLCPAAYTGILCEKLRCEEAGSCGSDSGQGAPPHGSPALLLLTTLLGTASPLVF
Sbjct: 379 CHNNVRCLCPAAYTGILCEKLRCEEAGSCGSDSGQGAPPHGSPALLLLTTLLGTASPLVF 438
>gi|164414431 netrin G1 isoform 1 [Homo sapiens]
Length = 539
Score = 834 bits (2155), Expect = 0.0
Identities = 421/551 (76%), Positives = 434/551 (78%), Gaps = 83/551 (15%)
Query: 1 MYLSRFLSIHALWVTVSSVMQPYPLVWGHYDLCKTQIYTEEGKVWDYMACQPESTDMTKY 60
MYLSRFLSIHALWVTVSSVMQPYPLVWGHYDLCKTQIYTEEGKVWDYMACQPESTDMTKY
Sbjct: 1 MYLSRFLSIHALWVTVSSVMQPYPLVWGHYDLCKTQIYTEEGKVWDYMACQPESTDMTKY 60
Query: 61 LKVKLDPPDITCGDPPETFCAMGNPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQS 120
LKVKLDPPDITCGDPPETFCAMGNPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQS
Sbjct: 61 LKVKLDPPDITCGDPPETFCAMGNPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQS 120
Query: 121 ATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYAT 180
ATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYAT
Sbjct: 121 ATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYAT 180
Query: 181 DCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNM 240
DCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNM
Sbjct: 181 DCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNM 240
Query: 241 ASLYGQLDTTKKLRDFFTVTDLRIRLLRPAVGEIFVDELHLARYFYAISDIKVRGRCKCN 300
ASLYGQLDTTKKLRDFFTVTDLRIRLLRPAVGEIFVDELHLARYFYAISDIKVRGRCKCN
Sbjct: 241 ASLYGQLDTTKKLRDFFTVTDLRIRLLRPAVGEIFVDELHLARYFYAISDIKVRGRCKCN 300
Query: 301 LHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISS 360
LHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISS
Sbjct: 301 LHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISS 360
Query: 361 IGNPPKFNRIWPNISSLEVSNPKQVAPKLALSTVSSVQVANHKRANVC------------ 408
IGN F S +++ L+TV V ++ R C
Sbjct: 361 IGNCECFGHS-NRCSYIDL-----------LNTVICVSCKHNTRGQHCELCRLGYFRNAS 408
Query: 409 ---DNELL----HCQNGGTCHNNVR----CLCPAAYTGILCEK----------------- 440
D+E + +C G+ H+ C C TG C++
Sbjct: 409 AQLDDENVCIECYCNPLGSIHDRCNGSGFCECKTGTTGPKCDECLPGNSWHYGCQPNVCD 468
Query: 441 -------------------------------LRCEEAGSCGSDSGQGAPPHGSPALLLLT 469
LRCEEAGSCGSDSGQGAPPHGSPALLLLT
Sbjct: 469 NELLHCQNGGTCHNNVRCLCPAAYTGILCEKLRCEEAGSCGSDSGQGAPPHGSPALLLLT 528
Query: 470 TLLGTASPLVF 480
TLLGTASPLVF
Sbjct: 529 TLLGTASPLVF 539
>gi|190014607 netrin G2 [Homo sapiens]
Length = 530
Score = 444 bits (1141), Expect = e-124
Identities = 215/439 (48%), Positives = 284/439 (64%), Gaps = 19/439 (4%)
Query: 24 PLVWGHYDLCKTQIYTEEGKVWDYMACQPESTDMTKYLKVKLDPPDITCGDPPETFCAMG 83
PL G YD+CK+ + T+EG W++ ACQP+ + Y+KVK++P ITCGDPPE FC+
Sbjct: 13 PLASGDYDICKSWVTTDEGPTWEFYACQPKVMRLKDYVKVKVEPSGITCGDPPERFCSHE 72
Query: 84 NPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIE 143
NPY+C+NECDAS P+LAHPP LMFD E +T+WQS TW YP PL+ NITLSW+KT+E
Sbjct: 73 NPYLCSNECDASNPDLAHPPRLMFDKEEEGLATYWQSITWSRYPSPLEANITLSWNKTVE 132
Query: 144 LTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQHTVLE 203
LTD++V+TFE GRP M+LEKSLD GRTWQPYQ+YA DC++AF M + +D+S +
Sbjct: 133 LTDDVVMTFEYGRPTVMVLEKSLDNGRTWQPYQFYAEDCMEAFGMSARRARDMSSSSAHR 192
Query: 204 IICTEEYST-GYTTNSKIIHFEIKDRFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDL 262
++CTEEYS + K + FE++DRFA FAGP LRNM +LY +L++ K L++FFT+TDL
Sbjct: 193 VLCTEEYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRLESAKGLKEFFTLTDL 252
Query: 263 RIRLLRPAVGEIFVDELHLARYFYAISDIKVRGRCKCNLHATVCVYDNSKLTCECEHNTT 322
R+RLLRPA+G +V +L +YFYAIS+I+V GRCKCNLHA +C L CECEHNTT
Sbjct: 253 RMRLLRPALGGTYVQRENLYKYFYAISNIEVIGRCKCNLHANLCSMREGSLQCECEHNTT 312
Query: 323 GPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNPPKFNRIWPNISSLEVSNP 382
GPDCGKCKKN++ R W GSYLP+P G+ N C + S GN + +
Sbjct: 313 GPDCGKCKKNFRTRSWRAGSYLPLPHGSPNAC-ATAGSFGNCECY------------GHS 359
Query: 383 KQVAPKLALSTVSSVQVANHKRANVCDNELLHCQNGGTCH---NNVRCLCPAAYTGILCE 439
+ + L+ V+ V ++ R C + L G+ NV C G + +
Sbjct: 360 NRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHD 419
Query: 440 KLRCEEAGSCGSDSGQGAP 458
RC E G C G P
Sbjct: 420 --RCNETGFCECREGAAGP 436
Score = 78.6 bits (192), Expect = 1e-14
Identities = 66/192 (34%), Positives = 87/192 (45%), Gaps = 22/192 (11%)
Query: 295 GRCKCNLHATVCVYDN--SKLTC-ECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTA 351
G C+C H+ C Y + + +TC C+HNT G C C+ Y + GS
Sbjct: 351 GNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGY----YRNGS---AELDDE 403
Query: 352 NTCIP-SISSIGNPPKFNRIWPNISSLEVSNPKQVAPKLALSTVSSVQVANHKRANVCDN 410
N CI + + IG+ +R N + PK + + NVCD+
Sbjct: 404 NVCIECNCNQIGSV--HDRC--NETGFCECREGAAGPKCD-DCLPTHYWRQGCYPNVCDD 458
Query: 411 ELLHCQNGGTCHNNVRCLCPAAYTGILCEKLRCEEA---GSCGSDSGQGAPPHGSPALLL 467
+ L CQNGGTC N RC CP YTG+ CE+ RC+ A G D GA P PA LL
Sbjct: 459 DQLLCQNGGTCLQNQRCACPRGYTGVRCEQPRCDPADDDGGLDCDRAPGAAPR--PATLL 516
Query: 468 -LTTLLGTASPL 478
LLG A+ L
Sbjct: 517 GCLLLLGLAARL 528
Score = 31.6 bits (70), Expect = 1.7
Identities = 17/56 (30%), Positives = 20/56 (35%), Gaps = 3/56 (5%)
Query: 288 ISDIKVRGRCKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSY 343
+ D V C CN +V N CEC GP C C + W G Y
Sbjct: 400 LDDENVCIECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHY---WRQGCY 452
>gi|148613884 netrin 1 [Homo sapiens]
Length = 604
Score = 173 bits (438), Expect = 4e-43
Identities = 98/276 (35%), Positives = 146/276 (52%), Gaps = 25/276 (9%)
Query: 71 TCGDPPETFCAMGNP----YMCNNECDASTPELAHPPELMFDFEGRHPSTFWQSATWKEY 126
TCG PP +C + + C+AS P+ AHPP + D H T WQS + ++
Sbjct: 69 TCGRPPARYCVVSERGEERLRSCHLCNASDPKKAHPPAFLTDLNNPHNLTCWQSENYLQF 128
Query: 127 PKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAF 186
P V +TLS K E+T + + F S RP+ M + KS+DYGRTW P+Q+Y+T C +
Sbjct: 129 PH--NVTLTLSLGKKFEVT-YVSLQFCSPRPESMAIYKSMDYGRTWVPFQFYSTQCRKMY 185
Query: 187 HMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNMASLYGQ 246
+ ++ +++ E +CT+ ++ + +I F D P +
Sbjct: 186 NRPHRA--PITKQNEQEAVCTDSHTDMRPLSGGLIAFSTLD-----GRPSAHD------- 231
Query: 247 LDTTKKLRDFFTVTDLRIRLLR-PAVGEIFVDELHLAR--YFYAISDIKVRGRCKCNLHA 303
D + L+D+ T TD+R+ R G+ D+ LAR YFYA+SD++V GRCKCN HA
Sbjct: 232 FDNSPVLQDWVTATDIRVAFSRLHTFGDENEDDSELARDSYFYAVSDLQVGGRCKCNGHA 291
Query: 304 TVCVYD-NSKLTCECEHNTTGPDCGKCKKNYQGRPW 338
CV D + L C+C HNT GP+C +CK + RPW
Sbjct: 292 ARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPW 327
Score = 29.3 bits (64), Expect = 8.3
Identities = 21/69 (30%), Positives = 29/69 (42%), Gaps = 7/69 (10%)
Query: 294 RGRCK-CNLHATVCVYDNSKLT---CECEHNTTGPDCGKCKKNYQ--GRPWSPGSYLPI- 346
R CK C+ H T C C+ TG C +C K YQ P +P +P+
Sbjct: 398 RKACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVA 457
Query: 347 PKGTANTCI 355
P TA + +
Sbjct: 458 PPTTAASSV 466
>gi|110611156 laminin, gamma 3 precursor [Homo sapiens]
Length = 1575
Score = 142 bits (359), Expect = 5e-34
Identities = 98/296 (33%), Positives = 138/296 (46%), Gaps = 32/296 (10%)
Query: 71 TCGDPPETFC----AMGNPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQSATWK-- 124
TCG PPE FC A G C CDA+ P+ H + DF + ST+WQS +
Sbjct: 53 TCGSPPEDFCPHVGAAGAGAHCQR-CDAADPQRHHNASYLTDFHSQDESTWWQSPSMAFG 111
Query: 125 -EYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCL 183
+YP VNITL K E+T + + F + RP+ + K W+PYQ+Y+ C
Sbjct: 112 VQYPT--SVNITLRLGKAYEIT-YVRLKFHTSRPESFAIYKRSRADGPWEPYQFYSASCQ 168
Query: 184 DAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNMASL 243
+ P+ CT E+S + + F L S
Sbjct: 169 KTYGR-PEGQYLRPGEDERVAFCTSEFSDISPLSGGNVAFST-----------LEGRPSA 216
Query: 244 YGQLDTTKKLRDFFTVTDLRIRL--LRPAVGEIFVDELHLARYFYAISDIKVRGRCKCNL 301
Y + + L+++ T T+L I L L +IF D L Y+YA+SD V GRCKCN
Sbjct: 217 YN-FEESPGLQEWVTSTELLISLDRLNTFGDDIFKDPKVLQSYYYAVSDFSVGGRCKCNG 275
Query: 302 HATVCVYDNS-KLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIP 356
HA+ C D + +L C C+HNTTG DC +C +Q RPW+ G+ A+ C+P
Sbjct: 276 HASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGT-----AEAAHECLP 326
Score = 41.6 bits (96), Expect = 0.002
Identities = 22/64 (34%), Positives = 30/64 (46%), Gaps = 7/64 (10%)
Query: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGS----YLPIPKGTAN 352
C CN H T D + C C H+T GP C +C + G P++ + P P +A
Sbjct: 707 CTCNQHGTC---DPNTGICVCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSAC 763
Query: 353 TCIP 356
T IP
Sbjct: 764 TTIP 767
Score = 29.6 bits (65), Expect = 6.3
Identities = 13/52 (25%), Positives = 21/52 (40%), Gaps = 10/52 (19%)
Query: 297 CKCNLHATVCVYDNSKLTC--------ECEHNTTGPDCGKCKKNYQGRPWSP 340
C C+ + C +D C +T GP C +C++N+ W P
Sbjct: 327 CNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFY--HWDP 376
Score = 29.3 bits (64), Expect = 8.3
Identities = 17/63 (26%), Positives = 26/63 (41%), Gaps = 5/63 (7%)
Query: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPI---PKGTANT 353
C C ++ + + TC C+ TG C +C + S G P P G+ +T
Sbjct: 383 CDCQSAGSLHLQCDDTGTCACKPTVTGWKCDRCLPGFHS--LSEGGCRPCTCNPAGSLDT 440
Query: 354 CIP 356
C P
Sbjct: 441 CDP 443
>gi|145309326 laminin, gamma 1 precursor [Homo sapiens]
Length = 1609
Score = 140 bits (353), Expect = 3e-33
Identities = 93/296 (31%), Positives = 136/296 (45%), Gaps = 32/296 (10%)
Query: 71 TCGDPPETFCAM----GNPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQSATWK-- 124
TCG PPE +C G C+ CDA P L H + D+ + +T+WQS T
Sbjct: 68 TCGTPPEEYCVQTGVTGVTKSCHL-CDAGQPHLQHGAAFLTDYNNQADTTWWQSQTMLAG 126
Query: 125 -EYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCL 183
+YP +N+TL K ++T + + F + RP+ + K W PYQYY+ C
Sbjct: 127 VQYPS--SINLTLHLGKAFDIT-YVRLKFHTSRPESFAIYKRTREDGPWIPYQYYSGSCE 183
Query: 184 DAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNMASL 243
+ + + + +CT+E+S + F L S
Sbjct: 184 NTYSKANRGFIRTGGDEQ-QALCTDEFSDISPLTGGNVAFST-----------LEGRPSA 231
Query: 244 YGQLDTTKKLRDFFTVTDLRIRL--LRPAVGEIFVDELHLARYFYAISDIKVRGRCKCNL 301
Y D + L+++ T TD+R+ L L E+F D L Y+YAISD V GRCKCN
Sbjct: 232 YN-FDNSPVLQEWVTATDIRVTLNRLNTFGDEVFNDPKVLKSYYYAISDFAVGGRCKCNG 290
Query: 302 HATVCVYDN-SKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIP 356
HA+ C+ + KL C C+HNT G DC KC + RPW + +A+ C+P
Sbjct: 291 HASECMKNEFDKLVCNCKHNTYGVDCEKCLPFFNDRPWRRAT-----AESASECLP 341
Score = 42.7 bits (99), Expect = 7e-04
Identities = 22/69 (31%), Positives = 28/69 (40%), Gaps = 6/69 (8%)
Query: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSY----LPIPKGTAN 352
C CN H+ C D C C NT GP C KC Y G + S P P G++
Sbjct: 724 CACNGHSETC--DPETGVCNCRDNTAGPHCEKCSDGYYGDSTAGTSSDCQPCPCPGGSSC 781
Query: 353 TCIPSISSI 361
+P +
Sbjct: 782 AVVPKTKEV 790
Score = 32.3 bits (72), Expect = 0.98
Identities = 38/152 (25%), Positives = 54/152 (35%), Gaps = 14/152 (9%)
Query: 297 CKCNLHATVCVYDN-SKLTCECE---HNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTAN 352
C+C+ + N ++LT EC +NT G C +CK + G P +P P K A
Sbjct: 828 CQCSDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRCKDGFFGNPLAPN---PADKCKAC 884
Query: 353 TCIPSISSIGNPPKFNRIWPNISSLEVSNPKQVAPKLALSTVSSVQVANHKRANVCDNEL 412
C + G + + P E P + + + CD
Sbjct: 885 NC----NLYGTMKQQSSCNPVTGQCECL-PHVTGQDCGACDPGFYNLQSGQGCERCDCHA 939
Query: 413 LHCQNGGTCHNNVRCLCPAAYTGILCEKLRCE 444
L NG +C C TG CE RCE
Sbjct: 940 LGSTNGQCDIRTGQCECQPGITGQHCE--RCE 969
Score = 30.0 bits (66), Expect = 4.9
Identities = 26/114 (22%), Positives = 42/114 (36%), Gaps = 16/114 (14%)
Query: 285 FYAISDIKVRGRCKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQG------RPW 338
F+ + + + C C+ ++ +S C C+ G C +C+ + RP
Sbjct: 386 FFRLGNNEACSSCHCSPVGSLSTQCDSYGRCSCKPGVMGDKCDRCQPGFHSLTEAGCRPC 445
Query: 339 SPGSYLPIPKGTANTCIPSISSI---GNPPKFN--RIWPNISSLEVSNPKQVAP 387
S P G+ + C N FN R P +LE SNP+ P
Sbjct: 446 SCD-----PSGSIDECNIETGRCVCKDNVEGFNCERCKPGFFNLESSNPRGCTP 494
Score = 30.0 bits (66), Expect = 4.9
Identities = 17/52 (32%), Positives = 25/52 (48%), Gaps = 1/52 (1%)
Query: 285 FYAISDIKVRGRCKCN-LHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQG 335
FY + + RC C+ L +T D CEC+ TG C +C+ N+ G
Sbjct: 923 FYNLQSGQGCERCDCHALGSTNGQCDIRTGQCECQPGITGQHCERCEVNHFG 974
Score = 30.0 bits (66), Expect = 4.9
Identities = 14/46 (30%), Positives = 21/46 (45%), Gaps = 2/46 (4%)
Query: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNY-QGRPWSPG 341
C C+ ++ + CEC G C +C++NY R W PG
Sbjct: 983 CDCHPEGSLSLQCKDDGRCECREGFVGNRCDQCEENYFYNRSW-PG 1027
>gi|21264602 laminin alpha 5 [Homo sapiens]
Length = 3695
Score = 127 bits (318), Expect = 3e-29
Identities = 94/310 (30%), Positives = 144/310 (46%), Gaps = 43/310 (13%)
Query: 58 TKYLKVKLDPPDITCGDPPETFCAMGNPYMCNNECDASTPELAHPPELMFDFEGRHPSTF 117
T+ L KL + GDP +T C+ C A+ AHP D R +
Sbjct: 77 TEDLYCKLVGGPVAGGDPNQTIRGQ----YCDI-CTAANSNKAHPASNAIDGTER----W 127
Query: 118 WQSATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQY 177
WQS + +VN+TL + + ++ S RPD +LE+S+D+GRT+QP+Q+
Sbjct: 128 WQSPPLSRGLEYNEVNVTLDLGQVFHVAYVLIKFANSPRPDLWVLERSMDFGRTYQPWQF 187
Query: 178 YAT---DCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAG 234
+A+ DCL+ F P++++ +++ ICT EY S+I+ E +
Sbjct: 188 FASSKRDCLERF--GPQTLERITRDDA--AICTTEY-------SRIVPLENGEIVVSLVN 236
Query: 235 PRLRNMASLYGQLDTTKKLRDFFTVTDLRIRLLRP------AVGEIFVDELHLARYFYAI 288
R M Y L LR+F T++R+R LR +G+ D RY+Y+I
Sbjct: 237 GRPGAMNFSYSPL-----LREFTKATNVRLRFLRTNTLLGHLMGKALRDPTVTRRYYYSI 291
Query: 289 SDIKVRGRCKCNLHATVC----VYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYL 344
DI + GRC C+ HA C D +L C C+HNT G C +C + +PW P +
Sbjct: 292 KDISIGGRCVCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPAT-- 349
Query: 345 PIPKGTANTC 354
+AN C
Sbjct: 350 ---ANSANEC 356
Score = 35.0 bits (79), Expect = 0.15
Identities = 38/170 (22%), Positives = 57/170 (33%), Gaps = 28/170 (16%)
Query: 297 CKCNLHATVCVYD-----------------NSKLTCECEHNTTGPDCGKCKKNYQGRPWS 339
C C HAT C YD + +C+H+TTG +C +C + P
Sbjct: 359 CNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNH 418
Query: 340 PGSYLPIPKG-------TANTCIPSISSIGNPPKFNRIWPNISSLEVSNPKQVAPKLALS 392
P + + T TC P F+ ++ + + P + S
Sbjct: 419 PLDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCYPTPSSS 478
Query: 393 TVSSVQVANHKRANVCDNELLHCQNGGTCHNNV---RCLCPAAYTGILCE 439
+ QV + CD Q G C + RCLC + G CE
Sbjct: 479 NDTREQVLPAGQIVNCDCSAAGTQ-GNACRKDPRVGRCLCKPNFQGTHCE 527
Score = 33.9 bits (76), Expect = 0.34
Identities = 16/54 (29%), Positives = 28/54 (51%), Gaps = 4/54 (7%)
Query: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNY---QGRPWSPGSYLPIP 347
C+C+ H+ C+ S + +C+HNT G C +C+ + + P +P P P
Sbjct: 1864 CQCHGHSDRCL-PGSGVCVDCQHNTEGAHCERCQAGFVSSRDDPSAPCVSCPCP 1916
Score = 31.2 bits (69), Expect = 2.2
Identities = 48/184 (26%), Positives = 66/184 (35%), Gaps = 36/184 (19%)
Query: 296 RCKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPW---SPGS-----YLPIP 347
RC C T ++ C C N +G C C + + G P +P S +P
Sbjct: 428 RCNCESDFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLP 487
Query: 348 KGTANTCIPSISSI-GN----PPKFNRIW--PNI--SSLEVSNPKQVAPKLALSTVSSVQ 398
G C S + GN P+ R PN + E+ P P SS
Sbjct: 488 AGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCAPGFYGPGCQPCQCSSPG 547
Query: 399 VANHKRANVCDNELLHCQ-----NGGTC--------HNNVRCLCPAAYTGILCEKLRCEE 445
VA+ + CD + C+ G TC H + LC + G L E C+E
Sbjct: 548 VADDR----CDPDTGQCRCRVGFEGATCDRCAPGYFHFPLCQLCGCSPAGTLPE--GCDE 601
Query: 446 AGSC 449
AG C
Sbjct: 602 AGRC 605
Score = 30.0 bits (66), Expect = 4.9
Identities = 16/51 (31%), Positives = 17/51 (33%), Gaps = 3/51 (5%)
Query: 315 CECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNPP 365
C C T GP C +C Y G P P G C P PP
Sbjct: 2088 CHCRPGTMGPQCRECAPGYWGLPEQGCRRCQCPGG---RCDPHTGRCNCPP 2135
Score = 29.3 bits (64), Expect = 8.3
Identities = 12/41 (29%), Positives = 18/41 (43%)
Query: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRP 337
C C+ T+ + C C+ GP C +C+ Y G P
Sbjct: 587 CGCSPAGTLPEGCDEAGRCLCQPEFAGPHCDRCRPGYHGFP 627
>gi|5453810 netrin 3 [Homo sapiens]
Length = 580
Score = 123 bits (308), Expect = 4e-28
Identities = 87/270 (32%), Positives = 124/270 (45%), Gaps = 32/270 (11%)
Query: 71 TCGDPPETFCAMGNPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQSATWKEYPKPL 130
TCG P CDAS P AH P L+ G W+S + PL
Sbjct: 58 TCGRP------------ATRACDASDPRRAHSPALLTSPGGTASPLCWRSESLPR--APL 103
Query: 131 QVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDC-LDAFHMD 189
V +T+ K EL + + F S P + L KS D+GR+W P ++++ C LD +
Sbjct: 104 NVTLTVPLGKAFELVF-VSLRFCSAPPASVALLKSQDHGRSWAPLGFFSSHCDLDYGRLP 162
Query: 190 PKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNMASLYGQLDT 249
+ E +C S ++ F ++D + P L LD+
Sbjct: 163 APANGPAGPGP--EALCFPA-PLAQPDGSGLLAFSMQDS----SPPGL--------DLDS 207
Query: 250 TKKLRDFFTVTDLRIRLLRPAVGEIFVDELHLARYFYAISDIKVRGRCKCNLHATVCVYD 309
+ L+D+ T TD+R+ L RP+ D + Y YA +D++V GRCKCN HA+ C+ D
Sbjct: 208 SPVLQDWVTATDVRVVLTRPSTAGDPRDMEAVVPYSYAATDLQVGGRCKCNGHASRCLLD 267
Query: 310 -NSKLTCECEHNTTGPDCGKCKKNYQGRPW 338
L C+C H T GPDCG+CK Y RPW
Sbjct: 268 TQGHLICDCRHGTEGPDCGRCKPFYCDRPW 297
Score = 29.3 bits (64), Expect = 8.3
Identities = 19/70 (27%), Positives = 31/70 (44%), Gaps = 3/70 (4%)
Query: 287 AISDIKVRGRCKCN-LHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQ--GRPWSPGSY 343
A+SD + C C+ + A + + C C+ TG C +C +Q P +P
Sbjct: 364 ALSDRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGFQQSRSPVAPCVK 423
Query: 344 LPIPKGTANT 353
PIP T ++
Sbjct: 424 TPIPGPTEDS 433
>gi|93204871 netrin 4 [Homo sapiens]
Length = 628
Score = 120 bits (302), Expect = 2e-27
Identities = 87/318 (27%), Positives = 144/318 (45%), Gaps = 69/318 (21%)
Query: 43 KVWDYMACQPESTDMTKYLKVKLDPPDITCGDPPETFCAMGNPYMCNNECDASTPELAHP 102
K+W C +T++ + + D+TC P C+ +C+A+ P LAH
Sbjct: 46 KLWADTTCGQNATELYCFYS---ENTDLTCRQPK-----------CD-KCNAAYPHLAHL 90
Query: 103 PELMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMIL 162
P M D R P T+WQSA + + +Q+++ + T ++++ F+S RP M+L
Sbjct: 91 PSAMADSSFRFPRTWWQSAE-DVHREKIQLDLEAEFYFT-----HLIVMFKSPRPAAMVL 144
Query: 163 EKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIH 222
++S D+G+TW+PY+Y+AT+C F ++ VK ICT +YS+ + +
Sbjct: 145 DRSQDFGKTWKPYKYFATNCSATFGLEDDVVKK-------GAICTSKYSSPFPCTGGEVI 197
Query: 223 FEIKDRFAFFAGPRLRNMASLYGQLDT----TKKLRDFFTVTDLRIRLLRPAV-----GE 273
F+ +L DT + K+++ +T+LR++LL+ +
Sbjct: 198 FK-----------------ALSPPYDTENPYSAKVQEQLKITNLRVQLLKRQSCPCQRND 240
Query: 274 IFVDELHLARYFYAISDIKVRGRCKCNLHATVCV-------------YDNSKLTCECEHN 320
+ + H YAI D V+G C CN HA C+ + C C+HN
Sbjct: 241 LNEEPQHFTH--YAIYDFIVKGSCFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCMCKHN 298
Query: 321 TTGPDCGKCKKNYQGRPW 338
T G C C Y RPW
Sbjct: 299 TAGSHCQHCAPLYNDRPW 316
Score = 37.7 bits (86), Expect = 0.023
Identities = 26/85 (30%), Positives = 36/85 (42%), Gaps = 24/85 (28%)
Query: 297 CKCNLHATVCVYD----------NSKLTCECEHNTTGPDCGKCKKNYQ---GRPWS---- 339
CKCN HA C +D + + +C+HNT G C +CK + RP+S
Sbjct: 332 CKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDA 391
Query: 340 --PGSYLPI-----PKGTANTCIPS 357
P S P+ P + C PS
Sbjct: 392 CKPCSCHPVGSAVLPANSVTFCDPS 416
>gi|38788416 laminin, alpha 1 precursor [Homo sapiens]
Length = 3075
Score = 116 bits (291), Expect = 4e-26
Identities = 95/314 (30%), Positives = 142/314 (45%), Gaps = 59/314 (18%)
Query: 71 TCGDP-PETFCAM-----GNPYMCNNECDASTPELAHPPELMFDFEGRHP--------ST 116
TCG+ PE FC + G P N +C A+P E RHP +
Sbjct: 40 TCGEKGPEMFCKLVEHVPGRPVR-NPQCRICDGNSANPRE-------RHPISHAIDGTNN 91
Query: 117 FWQSATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQ 176
+WQS + + + V ITL + ++ I+ + RP ILE+SLD G T+ P+Q
Sbjct: 92 WWQSPSIQNGREYHWVTITLDLRQVFQVAYVIIKAANAPRPGNWILERSLD-GTTFSPWQ 150
Query: 177 YYA---TDCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFA 233
YYA ++CL +++ P+ + E+ICT YS IH + +
Sbjct: 151 YYAVSDSECLSRYNITPRRGPP-TYRADDEVICTSYYSRLVPLEHGEIHTSLING----- 204
Query: 234 GPRLRNMASLYGQLDTTKKLRDFFTVTDLRIRL--LRPAVGEIF---------VDELHLA 282
R A D + KL +F + +R+RL +R ++ +D +
Sbjct: 205 ----RPSAD-----DLSPKLLEFTSARYIRLRLQRIRTLNADLMTLSHREPKELDPIVTR 255
Query: 283 RYFYAISDIKVRGRCKCNLHATVCVYDNS--KLTCECEHNTTGPDCGKCKKNYQGRPWSP 340
RY+Y+I DI V G C C HA+ C +D + KL C+CEHNT G C +C Y +PW P
Sbjct: 256 RYYYSIKDISVGGMCICYGHASSCPWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWRP 315
Query: 341 GSYLPIPKGTANTC 354
G+ + NTC
Sbjct: 316 GTV-----SSGNTC 324
Score = 36.6 bits (83), Expect = 0.052
Identities = 21/61 (34%), Positives = 26/61 (42%), Gaps = 13/61 (21%)
Query: 297 CKCNLHATVCVYDNSKLTC-ECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCI 355
C+C+ HA C N C C HNTTG C +C + G P +GT C
Sbjct: 742 CECHGHAAEC---NVHGVCIACAHNTTGVHCEQCLPGFYGEP---------SRGTPGDCQ 789
Query: 356 P 356
P
Sbjct: 790 P 790
Score = 33.5 bits (75), Expect = 0.44
Identities = 14/42 (33%), Positives = 22/42 (52%), Gaps = 5/42 (11%)
Query: 297 CKCNL---HATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQG 335
C+C++ H+ VC + C+C+ N TG C +C Y G
Sbjct: 902 CECHVKGSHSAVCHLETG--LCDCKPNVTGQQCDQCLHGYYG 941
Score = 32.7 bits (73), Expect = 0.75
Identities = 14/40 (35%), Positives = 17/40 (42%), Gaps = 1/40 (2%)
Query: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGR 336
C CN H+ C + K C NT G C C Y G+
Sbjct: 1403 CSCNNHSDTCDPNTGKCL-NCGDNTAGDHCDVCTSGYYGK 1441
Score = 31.6 bits (70), Expect = 1.7
Identities = 11/33 (33%), Positives = 16/33 (48%)
Query: 299 CNLHATVCVYDNSKLTCECEHNTTGPDCGKCKK 331
CNL +C C C+ N GP C +C++
Sbjct: 1102 CNLEQGLCGCVEETGACPCKENVFGPQCNECRE 1134
Score = 29.3 bits (64), Expect = 8.3
Identities = 18/70 (25%), Positives = 25/70 (35%), Gaps = 3/70 (4%)
Query: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIP-KGTANTCI 355
C C++ +V + C C G C +C + + GS P T NTC
Sbjct: 951 CNCSVAGSVSDGCTDEGQCHCVPGVAGKRCDRCAHGFYA--YQDGSCTPCDCPHTQNTCD 1008
Query: 356 PSISSIGNPP 365
P PP
Sbjct: 1009 PETGECVCPP 1018
>gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens]
Length = 3333
Score = 116 bits (290), Expect = 5e-26
Identities = 85/304 (27%), Positives = 133/304 (43%), Gaps = 52/304 (17%)
Query: 71 TCGD--------PPETFC-------AMGNPYMCNNE----CDASTPELAHPPELMFDFEG 111
TCG+ PE +C A G+ + + C++ P AHP D
Sbjct: 65 TCGERGPGEGRPQPELYCKLVGGPTAPGSGHTIQGQFCDYCNSEDPRKAHPVTNAIDGSE 124
Query: 112 RHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRT 171
R +WQS + +VN+TL + + ++ S RPD +LE+S+D+G T
Sbjct: 125 R----WWQSPPLSSGTQYNRVNLTLDLGQLFHVAYILIKFANSPRPDLWVLERSVDFGST 180
Query: 172 WQPYQYYA---TDCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGY-TTNSKIIHFEIKD 227
+ P+QY+A DCL F + +++C EYS N +++ I
Sbjct: 181 YSPWQYFAHSKVDCLKEFGREANMAVTRDD----DVLCVTEYSRIVPLENGEVVVSLING 236
Query: 228 RFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDLRIRLLRP------AVGEIFVDELHL 281
R P +N + LR+F T++R+R LR + + D
Sbjct: 237 R------PGAKNFT-------FSHTLREFTKATNIRLRFLRTNTLLGHLISKAQRDPTVT 283
Query: 282 ARYFYAISDIKVRGRCKCNLHATVCVYDNSK--LTCECEHNTTGPDCGKCKKNYQGRPWS 339
RY+Y+I DI + G+C CN HA VC +N + CEC+H+T G C +C Y R W
Sbjct: 284 RRYYYSIKDISIGGQCVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWR 343
Query: 340 PGSY 343
P ++
Sbjct: 344 PAAW 347
Score = 42.0 bits (97), Expect = 0.001
Identities = 16/39 (41%), Positives = 22/39 (56%), Gaps = 1/39 (2%)
Query: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQG 335
C CN H+ C D S + C+HNT G C +C++ Y G
Sbjct: 1687 CNCNGHSNQC-QDGSGICVNCQHNTAGEHCERCQEGYYG 1724
Score = 38.1 bits (87), Expect = 0.018
Identities = 22/77 (28%), Positives = 31/77 (40%), Gaps = 24/77 (31%)
Query: 297 CKCNLHATVCVYD-----------------NSKLTCECEHNTTGPDCGKCKKNYQGRPWS 339
C C+ HA+ C YD + C+HNT G +C +C K Y RP+
Sbjct: 356 CNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYY-RPYG 414
Query: 340 PGSYLPIPKGTANTCIP 356
+P + CIP
Sbjct: 415 ------VPVDAPDGCIP 425
Score = 36.2 bits (82), Expect = 0.068
Identities = 16/44 (36%), Positives = 20/44 (45%), Gaps = 3/44 (6%)
Query: 297 CKC---NLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRP 337
C C N AT CV + + C C+ TG C +C Y G P
Sbjct: 1734 CPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNP 1777
>gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens]
Length = 3277
Score = 116 bits (290), Expect = 5e-26
Identities = 85/304 (27%), Positives = 133/304 (43%), Gaps = 52/304 (17%)
Query: 71 TCGD--------PPETFC-------AMGNPYMCNNE----CDASTPELAHPPELMFDFEG 111
TCG+ PE +C A G+ + + C++ P AHP D
Sbjct: 65 TCGERGPGEGRPQPELYCKLVGGPTAPGSGHTIQGQFCDYCNSEDPRKAHPVTNAIDGSE 124
Query: 112 RHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRT 171
R +WQS + +VN+TL + + ++ S RPD +LE+S+D+G T
Sbjct: 125 R----WWQSPPLSSGTQYNRVNLTLDLGQLFHVAYILIKFANSPRPDLWVLERSVDFGST 180
Query: 172 WQPYQYYA---TDCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGY-TTNSKIIHFEIKD 227
+ P+QY+A DCL F + +++C EYS N +++ I
Sbjct: 181 YSPWQYFAHSKVDCLKEFGREANMAVTRDD----DVLCVTEYSRIVPLENGEVVVSLING 236
Query: 228 RFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDLRIRLLRP------AVGEIFVDELHL 281
R P +N + LR+F T++R+R LR + + D
Sbjct: 237 R------PGAKNFT-------FSHTLREFTKATNIRLRFLRTNTLLGHLISKAQRDPTVT 283
Query: 282 ARYFYAISDIKVRGRCKCNLHATVCVYDNSK--LTCECEHNTTGPDCGKCKKNYQGRPWS 339
RY+Y+I DI + G+C CN HA VC +N + CEC+H+T G C +C Y R W
Sbjct: 284 RRYYYSIKDISIGGQCVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWR 343
Query: 340 PGSY 343
P ++
Sbjct: 344 PAAW 347
Score = 42.0 bits (97), Expect = 0.001
Identities = 16/39 (41%), Positives = 22/39 (56%), Gaps = 1/39 (2%)
Query: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQG 335
C CN H+ C D S + C+HNT G C +C++ Y G
Sbjct: 1687 CNCNGHSNQC-QDGSGICVNCQHNTAGEHCERCQEGYYG 1724
Score = 38.1 bits (87), Expect = 0.018
Identities = 22/77 (28%), Positives = 31/77 (40%), Gaps = 24/77 (31%)
Query: 297 CKCNLHATVCVYD-----------------NSKLTCECEHNTTGPDCGKCKKNYQGRPWS 339
C C+ HA+ C YD + C+HNT G +C +C K Y RP+
Sbjct: 356 CNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYY-RPYG 414
Query: 340 PGSYLPIPKGTANTCIP 356
+P + CIP
Sbjct: 415 ------VPVDAPDGCIP 425
Score = 36.2 bits (82), Expect = 0.068
Identities = 16/44 (36%), Positives = 20/44 (45%), Gaps = 3/44 (6%)
Query: 297 CKC---NLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRP 337
C C N AT CV + + C C+ TG C +C Y G P
Sbjct: 1734 CPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNP 1777
>gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo
sapiens]
Length = 3118
Score = 110 bits (274), Expect = 4e-24
Identities = 91/311 (29%), Positives = 142/311 (45%), Gaps = 48/311 (15%)
Query: 71 TCGDP-PETFCAM-----GNPYMCNNEC-----DASTPELAHPPELMFDFEGRHPSTFWQ 119
TCG+ PE +C + G P N +C ++S P HP D + +T+WQ
Sbjct: 57 TCGEKGPEMYCKLVEHVPGQPVR-NPQCRICNQNSSNPNQRHPITNAIDGK----NTWWQ 111
Query: 120 SATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYA 179
S + K + V ITL + ++ IV S RP ILE+SLD ++P+QY+A
Sbjct: 112 SPSIKNGIEYHYVTITLDLQQVFQIAYVIVKAANSPRPGNWILERSLD-DVEYKPWQYHA 170
Query: 180 ---TDCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPR 236
T+CL +++ P++ S E+ICT YS + + IH + +
Sbjct: 171 VTDTECLTLYNIYPRTGPP-SYAKDDEVICTSFYSKIHPLENGEIHISLING-------- 221
Query: 237 LRNMASLYGQLDTTKKLRDFFTVTDLRIRL--LRPAVGEIF---------VDELHLARYF 285
R A D + +L +F + +R+R +R ++ +D + RY+
Sbjct: 222 -RPSAD-----DPSPELLEFTSARYIRLRFQRIRTLNADLMMFAHKDPREIDPIVTRRYY 275
Query: 286 YAISDIKVRGRCKCNLHATVCVYD--NSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSY 343
Y++ DI V G C C HA C D +K CECEHNT G C +C + +PW G++
Sbjct: 276 YSVKDISVGGMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTF 335
Query: 344 LPIPKGTANTC 354
L + A C
Sbjct: 336 LTKTECEACNC 346
Score = 39.3 bits (90), Expect = 0.008
Identities = 24/71 (33%), Positives = 33/71 (46%), Gaps = 15/71 (21%)
Query: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTC-- 354
C+CN H+++C + S + C+H+T G C +C Y G I KG N C
Sbjct: 1420 CQCNGHSSLCDPETS-ICQNCQHHTAGDFCERCALGYYG----------IVKGLPNDCQQ 1468
Query: 355 --IPSISSIGN 363
P ISS N
Sbjct: 1469 CACPLISSSNN 1479
Score = 35.4 bits (80), Expect = 0.12
Identities = 22/69 (31%), Positives = 29/69 (42%), Gaps = 12/69 (17%)
Query: 297 CKCNLHATVCVYDNSKLTC-ECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCI 355
C+C HA C D+ C C+ +T GP C KC + G P KGT+ C
Sbjct: 757 CQCFGHAESC--DDVTGECLNCKDHTGGPYCDKCLPGFYGEP---------TKGTSEDCQ 805
Query: 356 PSISSIGNP 364
P + P
Sbjct: 806 PCACPLNIP 814
Score = 32.0 bits (71), Expect = 1.3
Identities = 44/178 (24%), Positives = 64/178 (35%), Gaps = 33/178 (18%)
Query: 297 CKCNLH------ATVCVYDNSK-LTCE-CEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPK 348
C C L+ + C D S L C+ C TGP C +C + Y G+P PG
Sbjct: 807 CACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPG------- 859
Query: 349 GTANTCIPSIS-SIGNPPKFNRIWPNISSLEVSNPKQVAPKLALSTVSSV-QVANHKRAN 406
G+ C + + P + + S + P L + K
Sbjct: 860 GSCQPCQCNDNLDFSIPGSCDSL---SGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQ 916
Query: 407 VCDNELLHCQNGGT----CHNNV-RCLCPAAYTGILCEKLRCEEAGSCGSDSGQGAPP 459
C C GG+ CH+ +C C A G C+K + AG+ G S +G P
Sbjct: 917 PC-----RCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCK---AGTFGLQSARGCVP 966
Score = 31.6 bits (70), Expect = 1.7
Identities = 19/54 (35%), Positives = 23/54 (42%), Gaps = 1/54 (1%)
Query: 278 ELHLARYFYAISDIKVRGRCKCNLHATVCVYDNSKL-TCECEHNTTGPDCGKCK 330
EL YF D K C+CN + +S+ CEC N G C KCK
Sbjct: 899 ELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCK 952
>gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo
sapiens]
Length = 3122
Score = 110 bits (274), Expect = 4e-24
Identities = 91/311 (29%), Positives = 142/311 (45%), Gaps = 48/311 (15%)
Query: 71 TCGDP-PETFCAM-----GNPYMCNNEC-----DASTPELAHPPELMFDFEGRHPSTFWQ 119
TCG+ PE +C + G P N +C ++S P HP D + +T+WQ
Sbjct: 57 TCGEKGPEMYCKLVEHVPGQPVR-NPQCRICNQNSSNPNQRHPITNAIDGK----NTWWQ 111
Query: 120 SATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYA 179
S + K + V ITL + ++ IV S RP ILE+SLD ++P+QY+A
Sbjct: 112 SPSIKNGIEYHYVTITLDLQQVFQIAYVIVKAANSPRPGNWILERSLD-DVEYKPWQYHA 170
Query: 180 ---TDCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPR 236
T+CL +++ P++ S E+ICT YS + + IH + +
Sbjct: 171 VTDTECLTLYNIYPRTGPP-SYAKDDEVICTSFYSKIHPLENGEIHISLING-------- 221
Query: 237 LRNMASLYGQLDTTKKLRDFFTVTDLRIRL--LRPAVGEIF---------VDELHLARYF 285
R A D + +L +F + +R+R +R ++ +D + RY+
Sbjct: 222 -RPSAD-----DPSPELLEFTSARYIRLRFQRIRTLNADLMMFAHKDPREIDPIVTRRYY 275
Query: 286 YAISDIKVRGRCKCNLHATVCVYD--NSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSY 343
Y++ DI V G C C HA C D +K CECEHNT G C +C + +PW G++
Sbjct: 276 YSVKDISVGGMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTF 335
Query: 344 LPIPKGTANTC 354
L + A C
Sbjct: 336 LTKTECEACNC 346
Score = 39.3 bits (90), Expect = 0.008
Identities = 24/71 (33%), Positives = 33/71 (46%), Gaps = 15/71 (21%)
Query: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTC-- 354
C+CN H+++C + S + C+H+T G C +C Y G I KG N C
Sbjct: 1420 CQCNGHSSLCDPETS-ICQNCQHHTAGDFCERCALGYYG----------IVKGLPNDCQQ 1468
Query: 355 --IPSISSIGN 363
P ISS N
Sbjct: 1469 CACPLISSSNN 1479
Score = 35.4 bits (80), Expect = 0.12
Identities = 22/69 (31%), Positives = 29/69 (42%), Gaps = 12/69 (17%)
Query: 297 CKCNLHATVCVYDNSKLTC-ECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCI 355
C+C HA C D+ C C+ +T GP C KC + G P KGT+ C
Sbjct: 757 CQCFGHAESC--DDVTGECLNCKDHTGGPYCDKCLPGFYGEP---------TKGTSEDCQ 805
Query: 356 PSISSIGNP 364
P + P
Sbjct: 806 PCACPLNIP 814
Score = 32.0 bits (71), Expect = 1.3
Identities = 44/178 (24%), Positives = 64/178 (35%), Gaps = 33/178 (18%)
Query: 297 CKCNLH------ATVCVYDNSK-LTCE-CEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPK 348
C C L+ + C D S L C+ C TGP C +C + Y G+P PG
Sbjct: 807 CACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPG------- 859
Query: 349 GTANTCIPSIS-SIGNPPKFNRIWPNISSLEVSNPKQVAPKLALSTVSSV-QVANHKRAN 406
G+ C + + P + + S + P L + K
Sbjct: 860 GSCQPCQCNDNLDFSIPGSCDSL---SGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQ 916
Query: 407 VCDNELLHCQNGGT----CHNNV-RCLCPAAYTGILCEKLRCEEAGSCGSDSGQGAPP 459
C C GG+ CH+ +C C A G C+K + AG+ G S +G P
Sbjct: 917 PC-----RCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCK---AGTFGLQSARGCVP 966
Score = 31.6 bits (70), Expect = 1.7
Identities = 19/54 (35%), Positives = 23/54 (42%), Gaps = 1/54 (1%)
Query: 278 ELHLARYFYAISDIKVRGRCKCNLHATVCVYDNSKL-TCECEHNTTGPDCGKCK 330
EL YF D K C+CN + +S+ CEC N G C KCK
Sbjct: 899 ELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCK 952
>gi|143770880 laminin, beta 4 [Homo sapiens]
Length = 1761
Score = 103 bits (256), Expect = 5e-22
Identities = 86/331 (25%), Positives = 150/331 (45%), Gaps = 68/331 (20%)
Query: 49 ACQPESTDMTKYLKVKLDPPDITCG-DPPETFCAMGNPYMCNNE----CDASTP------ 97
AC P + D+ +L TCG + +C + Y+ + CD+ P
Sbjct: 27 ACHPTTGDLLVGRNTQLMASS-TCGLSRAQKYCILS--YLEGEQKCFICDSRFPYDPYDQ 83
Query: 98 ELAHPPE-LMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGR 156
+H E ++ FE +WQS ++ V+I L + ++++TF++ R
Sbjct: 84 PNSHTIENVIVSFEPDREKKWWQSENGLDH-----VSIRLDLEALFRFS-HLILTFKTFR 137
Query: 157 PDQMILEKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQHTVLEIICTEEY-----S 211
P M++E+S DYG W+ ++Y+A DC +F ++ V +I+C +Y S
Sbjct: 138 PAAMLVERSTDYGHNWKVFKYFAKDCATSF----PNITSGQAQGVGDIVCDSKYSDIEPS 193
Query: 212 TGYTTNSKII--HFEIKDRFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDLRIRLLR- 268
TG K++ FEI++ ++ + ++D T+T+LRI +
Sbjct: 194 TGGEVVLKVLDPSFEIENPYSPY--------------------IQDLVTLTNLRINFTKL 233
Query: 269 PAVGEIFVDELH---LARYFYAISDIKVRGRCKCNLHATVC---------VYDNSKLT-- 314
+G+ + L +Y+YA+ ++ VRG C CN HA+ C V+ +
Sbjct: 234 HTLGDALLGRRQNDSLDKYYYALYEMIVRGSCFCNGHASECRPMQKMRGDVFSPPGMVHG 293
Query: 315 -CECEHNTTGPDCGKCKKNYQGRPWSPGSYL 344
C C+HNT GP+C +CK +Q PW P + L
Sbjct: 294 QCVCQHNTDGPNCERCKDFFQDAPWRPAADL 324
Score = 36.6 bits (83), Expect = 0.052
Identities = 42/177 (23%), Positives = 64/177 (36%), Gaps = 53/177 (29%)
Query: 297 CKCNLHATVCVYDNSKL---------TCE-CEHNTTGPDCGKCKKNYQGRPW----SPGS 342
C CN H++ C +D + CE C+HNT G C +C+ + P P +
Sbjct: 332 CSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYA 391
Query: 343 YLPI---PKGT--ANTCI----PSISSIGNP---------PKFNRIWPNISSLEVSNPKQ 384
+P P GT C+ P++ S+ K ++ PN L ++P
Sbjct: 392 CIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLG 451
Query: 385 VAPKLALSTVSSVQVANHKRANVCDNELLHCQNGGTCH-NNVRCLCPAAYTGILCEK 440
P CD L TC + +CLC + TG CE+
Sbjct: 452 CQP--------------------CDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEE 488
Score = 30.8 bits (68), Expect = 2.8
Identities = 17/44 (38%), Positives = 21/44 (47%), Gaps = 3/44 (6%)
Query: 297 CKCNLHATVCVYDNSKLTC-ECEHNTTGPDCGKCKKNYQGRPWS 339
C CN A +C D +C C TTG +C +C Y G P S
Sbjct: 863 CPCNRFAELC--DPETGSCFNCGGFTTGRNCERCIDGYYGNPSS 904
Score = 30.8 bits (68), Expect = 2.8
Identities = 15/42 (35%), Positives = 20/42 (47%), Gaps = 2/42 (4%)
Query: 315 CECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIP 356
C C+ G C +C++NY G P PG +P A T P
Sbjct: 1099 CPCKLGYGGKRCSECQENYYGDP--PGRCIPCDCNRAGTQKP 1138
Score = 30.4 bits (67), Expect = 3.7
Identities = 11/33 (33%), Positives = 16/33 (48%)
Query: 310 NSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGS 342
+S + C C TG CG+C + G P G+
Sbjct: 933 SSDVICNCLQGYTGTQCGECSTGFYGNPRISGA 965
>gi|167614504 laminin, beta 1 precursor [Homo sapiens]
Length = 1786
Score = 98.6 bits (244), Expect = 1e-20
Identities = 91/348 (26%), Positives = 150/348 (43%), Gaps = 63/348 (18%)
Query: 25 LVWGHYDLCKTQIYTEEGKVWDYMA---CQPESTDMTKYLKVKLDPPDITCG-DPPETFC 80
L + LC+ ++ +E + A C P + D+ KL TCG PE +C
Sbjct: 7 LAFSFLALCRARVRAQEPEFSYGCAEGSCYPATGDLLIGRAQKLSVTS-TCGLHKPEPYC 65
Query: 81 AMGNP------YMCNNEC---DASTPELAHPPELMFDFEGRHPSTFWQSATWKEYPKPLQ 131
+ + ++CN++ + P+ ++ F +WQS E
Sbjct: 66 IVSHLQEDKKCFICNSQDPYHETLNPDSHLIENVVTTFAPNRLKIWWQSENGVE-----N 120
Query: 132 VNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAFHMDPK 191
V I L T ++++TF++ RP M++E+S D+G+TW Y+Y+A DC +F
Sbjct: 121 VTIQLDLEAEFHFT-HLIMTFKTFRPAAMLIERSSDFGKTWGVYRYFAYDCEASF----P 175
Query: 192 SVKDLSQHTVLEIICTEEYS-TGYTTNSKIIH------FEIKDRFAFFAGPRLRNMASLY 244
+ V +IIC YS +T ++I F+I+D ++ PR++N+
Sbjct: 176 GISTGPMKKVDDIICDSRYSDIEPSTEGEVIFRALDPAFKIEDPYS----PRIQNL---- 227
Query: 245 GQLDTTKKLRDFFTVTDLRIRLLR-PAVGEIFVDELHLAR--YFYAISDIKVRGRCKCNL 301
+T+LRI+ ++ +G+ +D R Y+YA+ D+ VRG C C
Sbjct: 228 ------------LKITNLRIKFVKLHTLGDNLLDSRMEIREKYYYAVYDMVVRGNCFCYG 275
Query: 302 HATVC---------VYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSP 340
HA+ C V C C HNT G +C C Y PW P
Sbjct: 276 HASECAPVDGFNEEVEGMVHGHCMCRHNTKGLNCELCMDFYHDLPWRP 323
Score = 31.2 bits (69), Expect = 2.2
Identities = 17/54 (31%), Positives = 23/54 (42%), Gaps = 6/54 (11%)
Query: 285 FYAISDIKVRGRCKCN---LHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQG 335
F+ D++ R C C+ + C D S C C GP C KC + Y G
Sbjct: 1121 FWGDPDVECRA-CDCDPRGIETPQC--DQSTGQCVCVEGVEGPRCDKCTRGYSG 1171
Score = 30.4 bits (67), Expect = 3.7
Identities = 16/42 (38%), Positives = 20/42 (47%), Gaps = 3/42 (7%)
Query: 297 CKCNLHATVCVYDNSKLTC-ECEHNTTGPDCGKCKKNYQGRP 337
C+CN HA C D C C+ T G +C +C Y G P
Sbjct: 867 CQCNGHADDC--DPVTGECLNCQDYTMGHNCERCLAGYYGDP 906
>gi|62868217 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 97.4 bits (241), Expect = 2e-20
Identities = 83/317 (26%), Positives = 139/317 (43%), Gaps = 62/317 (19%)
Query: 49 ACQPESTDM----TKYLKVKLDPPDITCG-DPPETFCAM-GNPYMCNNECDASTPE--LA 100
AC P D+ T++L+ TCG PET+C G M +CD+ P +
Sbjct: 25 ACYPPVGDLLVGRTRFLRASS-----TCGLTKPETYCTQYGEWQMKCCKCDSRQPHNYYS 79
Query: 101 HPPELMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQM 160
H E + G P +WQS V++ L + +L + +++ F+ P M
Sbjct: 80 HRVENVASSSG--PMRWWQSQNDVN-----PVSLQLDLDRRFQLQE-VMMEFQGPMPAGM 131
Query: 161 ILEKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKI 220
++E+S D+G+TW+ YQY A DC F V+ + ++ C S N+++
Sbjct: 132 LIERSSDFGKTWRVYQYLAADCTSTF----PRVRQGRPQSWQDVRCQ---SLPQRPNARL 184
Query: 221 IHFEIKDRFAFFAGPRLRNMASLYGQLDTTK--KLRDFFTVTDLRIRLLRPAVGEIFVDE 278
+++ N+ L + T+ K+++ +T+LR+ R A +
Sbjct: 185 NGGKVQ-----------LNLMDLVSGIPATQSQKIQEVGEITNLRVNFTRLA--PVPQRG 231
Query: 279 LHLARYFYAISDIKVRGRCKCNLHATVC---------------VYDNSKLTCECEHNTTG 323
H +YA+S ++++G C C+ HA C V+D C C+HNT G
Sbjct: 232 YHPPSAYYAVSQLRLQGSCFCHGHADRCAPKPGASAGPSTAVQVHD----VCVCQHNTAG 287
Query: 324 PDCGKCKKNYQGRPWSP 340
P+C +C Y RPW P
Sbjct: 288 PNCERCAPFYNNRPWRP 304
Score = 30.4 bits (67), Expect = 3.7
Identities = 13/48 (27%), Positives = 21/48 (43%), Gaps = 10/48 (20%)
Query: 296 RCKCNLHATVCVYDNSKLTC----------ECEHNTTGPDCGKCKKNY 333
RC CN H+ C +D + C +T G +C +C+ +Y
Sbjct: 315 RCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHY 362
>gi|62868215 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 97.4 bits (241), Expect = 2e-20
Identities = 83/317 (26%), Positives = 139/317 (43%), Gaps = 62/317 (19%)
Query: 49 ACQPESTDM----TKYLKVKLDPPDITCG-DPPETFCAM-GNPYMCNNECDASTPE--LA 100
AC P D+ T++L+ TCG PET+C G M +CD+ P +
Sbjct: 25 ACYPPVGDLLVGRTRFLRASS-----TCGLTKPETYCTQYGEWQMKCCKCDSRQPHNYYS 79
Query: 101 HPPELMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQM 160
H E + G P +WQS V++ L + +L + +++ F+ P M
Sbjct: 80 HRVENVASSSG--PMRWWQSQNDVN-----PVSLQLDLDRRFQLQE-VMMEFQGPMPAGM 131
Query: 161 ILEKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKI 220
++E+S D+G+TW+ YQY A DC F V+ + ++ C S N+++
Sbjct: 132 LIERSSDFGKTWRVYQYLAADCTSTF----PRVRQGRPQSWQDVRCQ---SLPQRPNARL 184
Query: 221 IHFEIKDRFAFFAGPRLRNMASLYGQLDTTK--KLRDFFTVTDLRIRLLRPAVGEIFVDE 278
+++ N+ L + T+ K+++ +T+LR+ R A +
Sbjct: 185 NGGKVQ-----------LNLMDLVSGIPATQSQKIQEVGEITNLRVNFTRLA--PVPQRG 231
Query: 279 LHLARYFYAISDIKVRGRCKCNLHATVC---------------VYDNSKLTCECEHNTTG 323
H +YA+S ++++G C C+ HA C V+D C C+HNT G
Sbjct: 232 YHPPSAYYAVSQLRLQGSCFCHGHADRCAPKPGASAGPSTAVQVHD----VCVCQHNTAG 287
Query: 324 PDCGKCKKNYQGRPWSP 340
P+C +C Y RPW P
Sbjct: 288 PNCERCAPFYNNRPWRP 304
Score = 30.4 bits (67), Expect = 3.7
Identities = 13/48 (27%), Positives = 21/48 (43%), Gaps = 10/48 (20%)
Query: 296 RCKCNLHATVCVYDNSKLTC----------ECEHNTTGPDCGKCKKNY 333
RC CN H+ C +D + C +T G +C +C+ +Y
Sbjct: 315 RCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHY 362
>gi|189083719 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 97.4 bits (241), Expect = 2e-20
Identities = 83/317 (26%), Positives = 139/317 (43%), Gaps = 62/317 (19%)
Query: 49 ACQPESTDM----TKYLKVKLDPPDITCG-DPPETFCAM-GNPYMCNNECDASTPE--LA 100
AC P D+ T++L+ TCG PET+C G M +CD+ P +
Sbjct: 25 ACYPPVGDLLVGRTRFLRASS-----TCGLTKPETYCTQYGEWQMKCCKCDSRQPHNYYS 79
Query: 101 HPPELMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQM 160
H E + G P +WQS V++ L + +L + +++ F+ P M
Sbjct: 80 HRVENVASSSG--PMRWWQSQNDVN-----PVSLQLDLDRRFQLQE-VMMEFQGPMPAGM 131
Query: 161 ILEKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKI 220
++E+S D+G+TW+ YQY A DC F V+ + ++ C S N+++
Sbjct: 132 LIERSSDFGKTWRVYQYLAADCTSTF----PRVRQGRPQSWQDVRCQ---SLPQRPNARL 184
Query: 221 IHFEIKDRFAFFAGPRLRNMASLYGQLDTTK--KLRDFFTVTDLRIRLLRPAVGEIFVDE 278
+++ N+ L + T+ K+++ +T+LR+ R A +
Sbjct: 185 NGGKVQ-----------LNLMDLVSGIPATQSQKIQEVGEITNLRVNFTRLA--PVPQRG 231
Query: 279 LHLARYFYAISDIKVRGRCKCNLHATVC---------------VYDNSKLTCECEHNTTG 323
H +YA+S ++++G C C+ HA C V+D C C+HNT G
Sbjct: 232 YHPPSAYYAVSQLRLQGSCFCHGHADRCAPKPGASAGPSTAVQVHD----VCVCQHNTAG 287
Query: 324 PDCGKCKKNYQGRPWSP 340
P+C +C Y RPW P
Sbjct: 288 PNCERCAPFYNNRPWRP 304
Score = 30.4 bits (67), Expect = 3.7
Identities = 13/48 (27%), Positives = 21/48 (43%), Gaps = 10/48 (20%)
Query: 296 RCKCNLHATVCVYDNSKLTC----------ECEHNTTGPDCGKCKKNY 333
RC CN H+ C +D + C +T G +C +C+ +Y
Sbjct: 315 RCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHY 362
>gi|119703755 laminin, beta 2 precursor [Homo sapiens]
Length = 1798
Score = 90.9 bits (224), Expect = 2e-18
Identities = 77/314 (24%), Positives = 139/314 (44%), Gaps = 46/314 (14%)
Query: 49 ACQPESTDMTKYLKVKLDPPDITCG-DPPETFCAMGNP------YMCNNECDASTPELAH 101
+C P + D+ +L TCG + P+ +C + + ++C++ S + H
Sbjct: 46 SCYPATGDLLVGRADRLTASS-TCGLNGPQPYCIVSHLQDEKKCFLCDSRRPFSARDNPH 104
Query: 102 PPEL---MFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPD 158
+ + F + + +WQS E P V I L T ++++TF++ RP
Sbjct: 105 SHRIQNVVTSFAPQRRAAWWQS----ENGIPA-VTIQLDLEAEFHFT-HLIMTFKTFRPA 158
Query: 159 QMILEKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNS 218
M++E+S D+GRTW Y+Y++ DC F P + +H +++C YS +
Sbjct: 159 AMLVERSADFGRTWHVYRYFSYDCGADFPGVPLAP---PRHWD-DVVCESRYSEIEPSTE 214
Query: 219 KIIHFEIKDRFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDLRIRLLR-PAVGEIFVD 277
+ + + D P + ++++ +T+LR+ L R +G+ +D
Sbjct: 215 GEVIYRVLDPAIPIPDP-------------YSSRIQNLLKITNLRVNLTRLHTLGDNLLD 261
Query: 278 ELHLAR--YFYAISDIKVRGRCKCNLHATVCVYDNSKL---------TCECEHNTTGPDC 326
R Y+YA+ ++ VRG C C HA+ C C C+HNT G +C
Sbjct: 262 PRREIREKYYYALYELVVRGNCFCYGHASECAPAPGAPAHAEGMVHGACICKHNTRGLNC 321
Query: 327 GKCKKNYQGRPWSP 340
+C+ Y+ PW P
Sbjct: 322 EQCQDFYRDLPWRP 335
Score = 33.5 bits (75), Expect = 0.44
Identities = 17/47 (36%), Positives = 19/47 (40%), Gaps = 9/47 (19%)
Query: 296 RCKCNLHAT---------VCVYDNSKLTCECEHNTTGPDCGKCKKNY 333
RC CNL T C D S C C N GP C +C N+
Sbjct: 1037 RCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNF 1083
Score = 30.4 bits (67), Expect = 3.7
Identities = 17/52 (32%), Positives = 24/52 (46%), Gaps = 3/52 (5%)
Query: 287 AISDIKVRGRCKCNLHATV---CVYDNSKLTCECEHNTTGPDCGKCKKNYQG 335
+ISD RC+CN TV D + +C C+ TG C +C + G
Sbjct: 460 SISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWG 511
Score = 29.3 bits (64), Expect = 8.3
Identities = 12/38 (31%), Positives = 17/38 (44%), Gaps = 8/38 (21%)
Query: 299 CNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGR 336
C+ H C+ C H+T GP C CK + G+
Sbjct: 1000 CDPHTGQCL--------RCLHHTEGPHCAHCKPGFHGQ 1029
>gi|219842266 usherin isoform B [Homo sapiens]
Length = 5202
Score = 65.5 bits (158), Expect = 1e-10
Identities = 54/201 (26%), Positives = 88/201 (43%), Gaps = 28/201 (13%)
Query: 148 IVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQH---TVLEI 204
I+I F S +P ++ +++ + W+ +QY+A +C AF M K+ DL + L++
Sbjct: 385 IIIQFFSPQPTEIRIQRKKENSLDWEDWQYFARNC-GAFGM--KNNGDLEKPDSVNCLQL 441
Query: 205 ICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDLRI 264
YS G T S + GP R Y T L++F T +R
Sbjct: 442 SNFTPYSRGNVTFSILT-----------PGPNYRPG---YNNFYNTPSLQEFVKATQIRF 487
Query: 265 RLLRPAVGEIFVDE--LHLARYFYAISDIKVRGRCKCNLHATVCVYDNSKLTCEC--EHN 320
G+ + E ++L +YA+ +I + GRC+C+ HA C + C C E
Sbjct: 488 HFH----GQYYTTETAVNLRHRYYAVDEITISGRCQCHGHADNCDTTSQPYRCLCSQESF 543
Query: 321 TTGPDCGKCKKNYQGRPWSPG 341
T G C +C Y +P+ G
Sbjct: 544 TEGLHCDRCLPLYNDKPFRQG 564
Score = 37.0 bits (84), Expect = 0.040
Identities = 15/40 (37%), Positives = 22/40 (55%), Gaps = 1/40 (2%)
Query: 297 CKCNLHATVCVYDNSKL-TCECEHNTTGPDCGKCKKNYQG 335
C+CNLH +V + N CEC+ G C C++N+ G
Sbjct: 747 CQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYG 786
Score = 29.3 bits (64), Expect = 8.3
Identities = 48/199 (24%), Positives = 65/199 (32%), Gaps = 42/199 (21%)
Query: 283 RYFYAISDIKVRGRCKCN----LHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPW 338
RY I + + C+C+ L T+C D C C N G C +C+
Sbjct: 886 RYNLTIDNFQHCQMCECDSLGTLPGTIC--DPISGQCLCVPNRQGRRCNQCQ-------- 935
Query: 339 SPGSYLPIPKGTANTCIPSISSIGNPPKFNRIWPNISSLEVSNPKQVAPKLALSTVSSVQ 398
PG Y I G A C+P S N I +++ V +A + Q
Sbjct: 936 -PGFY--ISPGNATGCLP--CSCHTTGAVNHICNSLTGQCVCQDASIAGQ------RCDQ 984
Query: 399 VANH--------KRANVCDNELLHCQNGGTCH-NNVRCLCPAAYTGILCE-------KLR 442
+H R C+ L N TCH +C C TG C+ L
Sbjct: 985 CKDHYFGFDPQTGRCQPCNCHLSGALN-ETCHLVTGQCFCKQFVTGSKCDACVPSASHLD 1043
Query: 443 CEEAGSCGSDSGQGAPPHG 461
C Q PP G
Sbjct: 1044 VNNLLGCSKTPFQQPPPRG 1062
>gi|219842259 usherin isoform A [Homo sapiens]
Length = 1546
Score = 65.5 bits (158), Expect = 1e-10
Identities = 54/201 (26%), Positives = 88/201 (43%), Gaps = 28/201 (13%)
Query: 148 IVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQH---TVLEI 204
I+I F S +P ++ +++ + W+ +QY+A +C AF M K+ DL + L++
Sbjct: 385 IIIQFFSPQPTEIRIQRKKENSLDWEDWQYFARNC-GAFGM--KNNGDLEKPDSVNCLQL 441
Query: 205 ICTEEYSTGYTTNSKIIHFEIKDRFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDLRI 264
YS G T S + GP R Y T L++F T +R
Sbjct: 442 SNFTPYSRGNVTFSILT-----------PGPNYRPG---YNNFYNTPSLQEFVKATQIRF 487
Query: 265 RLLRPAVGEIFVDE--LHLARYFYAISDIKVRGRCKCNLHATVCVYDNSKLTCEC--EHN 320
G+ + E ++L +YA+ +I + GRC+C+ HA C + C C E
Sbjct: 488 HFH----GQYYTTETAVNLRHRYYAVDEITISGRCQCHGHADNCDTTSQPYRCLCSQESF 543
Query: 321 TTGPDCGKCKKNYQGRPWSPG 341
T G C +C Y +P+ G
Sbjct: 544 TEGLHCDRCLPLYNDKPFRQG 564
Score = 37.0 bits (84), Expect = 0.040
Identities = 15/40 (37%), Positives = 22/40 (55%), Gaps = 1/40 (2%)
Query: 297 CKCNLHATVCVYDNSKL-TCECEHNTTGPDCGKCKKNYQG 335
C+CNLH +V + N CEC+ G C C++N+ G
Sbjct: 747 CQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYG 786
Score = 29.3 bits (64), Expect = 8.3
Identities = 48/199 (24%), Positives = 65/199 (32%), Gaps = 42/199 (21%)
Query: 283 RYFYAISDIKVRGRCKCN----LHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPW 338
RY I + + C+C+ L T+C D C C N G C +C+
Sbjct: 886 RYNLTIDNFQHCQMCECDSLGTLPGTIC--DPISGQCLCVPNRQGRRCNQCQ-------- 935
Query: 339 SPGSYLPIPKGTANTCIPSISSIGNPPKFNRIWPNISSLEVSNPKQVAPKLALSTVSSVQ 398
PG Y I G A C+P S N I +++ V +A + Q
Sbjct: 936 -PGFY--ISPGNATGCLP--CSCHTTGAVNHICNSLTGQCVCQDASIAGQ------RCDQ 984
Query: 399 VANH--------KRANVCDNELLHCQNGGTCH-NNVRCLCPAAYTGILCE-------KLR 442
+H R C+ L N TCH +C C TG C+ L
Sbjct: 985 CKDHYFGFDPQTGRCQPCNCHLSGALN-ETCHLVTGQCFCKQFVTGSKCDACVPSASHLD 1043
Query: 443 CEEAGSCGSDSGQGAPPHG 461
C Q PP G
Sbjct: 1044 VNNLLGCSKTPFQQPPPRG 1062
>gi|24308065 netrin 5 [Homo sapiens]
Length = 489
Score = 54.7 bits (130), Expect = 2e-07
Identities = 20/50 (40%), Positives = 29/50 (58%)
Query: 293 VRGRCKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGS 342
+RGRC+C+ HA C C C H+TTGP C C+ +++ PW P +
Sbjct: 153 LRGRCQCHGHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPAT 202
Score = 32.0 bits (71), Expect = 1.3
Identities = 19/55 (34%), Positives = 24/55 (43%), Gaps = 12/55 (21%)
Query: 297 CKCNLHATVCVYDNSKL----------TCE-CEHNTTGPDCGKCKKNYQGRPWSP 340
C CN HA C + NS+L CE C H+T G C C+ + P P
Sbjct: 212 CSCNQHARRCRF-NSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQP 265
>gi|188528675 slit homolog 1 [Homo sapiens]
Length = 1534
Score = 46.6 bits (109), Expect = 5e-05
Identities = 23/55 (41%), Positives = 28/55 (50%), Gaps = 11/55 (20%)
Query: 415 CQNGGTCHNN----VRCLCPAAYTGILCE-------KLRCEEAGSCGSDSGQGAP 458
CQN GTCHN+ RC CP+ Y G CE CE G+C + G+ AP
Sbjct: 934 CQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDAP 988
Score = 32.3 bits (72), Expect = 0.98
Identities = 14/28 (50%), Positives = 16/28 (57%), Gaps = 3/28 (10%)
Query: 415 CQNGGTCHNNVR---CLCPAAYTGILCE 439
CQNG C + V CLC Y+G LCE
Sbjct: 1092 CQNGAQCMDEVNSYSCLCAEGYSGQLCE 1119
Score = 32.0 bits (71), Expect = 1.3
Identities = 14/30 (46%), Positives = 16/30 (53%), Gaps = 3/30 (10%)
Query: 415 CQNGGTCHN---NVRCLCPAAYTGILCEKL 441
C NGG C + N C CP Y G CE+L
Sbjct: 1014 CANGGVCVDGVGNYTCQCPLQYEGKACEQL 1043
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 43.5 bits (101), Expect = 4e-04
Identities = 24/62 (38%), Positives = 29/62 (46%), Gaps = 14/62 (22%)
Query: 297 CKCNLHATVC--VYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTC 354
C CN HA+ C VY + C+HNT GP C KCK + G K TA +C
Sbjct: 764 CNCNGHASSCDPVYGHC---LNCQHNTEGPQCNKCKAGFFG---------DAMKATATSC 811
Query: 355 IP 356
P
Sbjct: 812 RP 813
Score = 40.0 bits (92), Expect = 0.005
Identities = 20/46 (43%), Positives = 26/46 (56%), Gaps = 8/46 (17%)
Query: 415 CQNGGTCHNNVR----CLCPAAYTGILCE---KLRCEEAGSCGSDS 453
CQNGG CH++ C+CPA +TG CE L C +CG D+
Sbjct: 3853 CQNGGQCHDSESSSYVCVCPAGFTGSRCEHSQALHCHPE-ACGPDA 3897
Score = 38.9 bits (89), Expect = 0.010
Identities = 20/68 (29%), Positives = 29/68 (42%), Gaps = 10/68 (14%)
Query: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIP 356
C+CN H+ +C + + +C+HN G C C +PG Y GT C P
Sbjct: 1563 CECNGHSDLC-HPETGACSQCQHNAAGEFCELC---------APGYYGDATAGTPEDCQP 1612
Query: 357 SISSIGNP 364
+ NP
Sbjct: 1613 CACPLTNP 1620
Score = 37.0 bits (84), Expect = 0.040
Identities = 15/41 (36%), Positives = 23/41 (56%), Gaps = 3/41 (7%)
Query: 296 RCKCNLHATVCVYDNSKLTCE-CEHNTTGPDCGKCKKNYQG 335
RC C+ H+ C + C+ C+H+T GP C +C+ Y G
Sbjct: 1158 RCSCHGHSEACEPETG--ACQGCQHHTEGPRCEQCQPGYYG 1196
Score = 34.3 bits (77), Expect = 0.26
Identities = 21/75 (28%), Positives = 31/75 (41%), Gaps = 6/75 (8%)
Query: 371 WPNISSLEVSNPKQVAPKLALSTVSSVQVANHKRANV------CDNELLHCQNGGTCHNN 424
W + S V + + +L V V N K A+V D + H + G H+
Sbjct: 669 WVHESGRPVQRAELLQVLQSLEAVLIQTVYNTKMASVGLSDIAMDTTVTHATSHGRAHSV 728
Query: 425 VRCLCPAAYTGILCE 439
C CP Y+G+ CE
Sbjct: 729 EECRCPIGYSGLSCE 743
>gi|122937283 6720455I24Rik homolog [Homo sapiens]
Length = 1413
Score = 43.1 bits (100), Expect = 6e-04
Identities = 23/63 (36%), Positives = 31/63 (49%), Gaps = 12/63 (19%)
Query: 402 HKRANVCDNELLHCQNGGTCH---NNVRCLCPAAYTGILCEKLR-------CEEAGSCGS 451
H N C ++ CQNGGTC N+ RC CPA + G CE + C+ G C
Sbjct: 309 HLDVNECASQ--PCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQV 366
Query: 452 DSG 454
++G
Sbjct: 367 ENG 369
Score = 37.7 bits (86), Expect = 0.023
Identities = 21/67 (31%), Positives = 31/67 (46%), Gaps = 13/67 (19%)
Query: 400 ANHKRANVCDNELLHCQNGGTCH---NNVRCLCPAAYTGILCEKLR--------CEEAGS 448
A+H + CD++ C NGG+C ++ C CP + G CEK R C G+
Sbjct: 537 ASHSLPSPCDSD--PCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGT 594
Query: 449 CGSDSGQ 455
C G+
Sbjct: 595 CKEAGGE 601
Score = 37.0 bits (84), Expect = 0.040
Identities = 18/50 (36%), Positives = 23/50 (46%), Gaps = 10/50 (20%)
Query: 415 CQNGGTCHN---NVRCLCPAAYTGILCE-------KLRCEEAGSCGSDSG 454
C+NGG+C N C CPA + G+ CE C+ G C S G
Sbjct: 800 CRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGG 849
Score = 34.7 bits (78), Expect = 0.20
Identities = 17/52 (32%), Positives = 22/52 (42%), Gaps = 12/52 (23%)
Query: 415 CQNGGTC--HNNVRCLCPAAYTGILCE----------KLRCEEAGSCGSDSG 454
C+NGG C N C CP + G+LCE +C + G C G
Sbjct: 474 CRNGGRCLGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGG 525
Score = 33.5 bits (75), Expect = 0.44
Identities = 15/35 (42%), Positives = 20/35 (57%), Gaps = 5/35 (14%)
Query: 408 CDNELLHCQNGGTC---HNNVRCLCPAAYTGILCE 439
CD + CQ+GG C + + C+C A YTG CE
Sbjct: 353 CDTK--ECQHGGQCQVENGSAVCVCQAGYTGAACE 385
Score = 32.7 bits (73), Expect = 0.75
Identities = 41/168 (24%), Positives = 60/168 (35%), Gaps = 36/168 (21%)
Query: 297 CKCNL--HATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTC 354
C+C L +C ++ + + C NT PD G C ++ GSYL + N
Sbjct: 488 CQCPLGFFGLLCEFEITAMPCNM--NTQCPDGGYCMEH-------GGSYLCVCHTDHNAS 538
Query: 355 IPSISSIGNPPKFN--RIWPNISSLEVSNPKQVAPKLALSTVSSVQVANHKRANVCDNEL 412
S + P FN + S P+ K R ++C +
Sbjct: 539 HSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHC----------EKARPHLCSSG- 587
Query: 413 LHCQNGGTCHN---NVRCLCPAAYTGILCEKLR--------CEEAGSC 449
C+NGGTC C CP +TG CE + C G+C
Sbjct: 588 -PCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTC 634
Score = 32.7 bits (73), Expect = 0.75
Identities = 17/45 (37%), Positives = 20/45 (44%), Gaps = 10/45 (22%)
Query: 415 CQNGGTCHNNVR---CLCPAAYTGILCEKLR-------CEEAGSC 449
C +GG+C + V CLC Y G CE R C GSC
Sbjct: 762 CLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSC 806
Score = 32.0 bits (71), Expect = 1.3
Identities = 15/45 (33%), Positives = 22/45 (48%), Gaps = 10/45 (22%)
Query: 415 CQNGGTCHNNV---RCLCPAAYTGILCE-------KLRCEEAGSC 449
C NGGTC + + +C CP ++G CE + C G+C
Sbjct: 628 CHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTC 672
Score = 31.6 bits (70), Expect = 1.7
Identities = 41/174 (23%), Positives = 54/174 (31%), Gaps = 34/174 (19%)
Query: 306 CVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSI---- 361
CV N TC C TG C +P G TC I+S
Sbjct: 288 CVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGG----------TCTHGINSFRCQC 337
Query: 362 ----GNPPKFNRIWP-NISSLEVSNPKQVAPKLALSTVSSVQVANHKRANVCDNELLHCQ 416
G P P + + QV A+ + +V D C
Sbjct: 338 PAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPDPCL 397
Query: 417 NGGTCHN---NVRCLCPAAYTGILCE-----------KLRCEEAGSCGSDSGQG 456
NGG+C + N CLC + G+ CE C G+C D+ QG
Sbjct: 398 NGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTC-VDADQG 450
Score = 30.0 bits (66), Expect = 4.9
Identities = 17/59 (28%), Positives = 27/59 (45%), Gaps = 12/59 (20%)
Query: 406 NVCDNELLHCQNGGTCHNN---VRCLCPAAYTGILCEKLR-------CEEAGSCGSDSG 454
+ CD+ CQ+GG C + C+CP ++ G CE + C G C + +G
Sbjct: 831 DACDSS--PCQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNG 887
>gi|88702793 slit-like 2 [Homo sapiens]
Length = 673
Score = 42.7 bits (99), Expect = 7e-04
Identities = 22/53 (41%), Positives = 25/53 (47%), Gaps = 15/53 (28%)
Query: 415 CQNGGTCHNNVR----CLCPAAYTGILCEKLRCEEAGSCGSDSGQGAPPHGSP 463
C NGGTCH R CLCP +TG+ CE S GQG P +P
Sbjct: 414 CLNGGTCHLGTRHHLACLCPEGFTGLYCE-----------SQMGQGTRPSPTP 455
>gi|148833508 notch1 preproprotein [Homo sapiens]
Length = 2555
Score = 42.4 bits (98), Expect = 0.001
Identities = 21/54 (38%), Positives = 29/54 (53%), Gaps = 10/54 (18%)
Query: 406 NVCDNELLHCQNGGTCHNNV---RCLCPAAYTGILCEK-------LRCEEAGSC 449
N C + C++GGTCHN V RC+C A +TG CE+ C+ G+C
Sbjct: 180 NECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTC 233
Score = 38.5 bits (88), Expect = 0.014
Identities = 20/54 (37%), Positives = 27/54 (50%), Gaps = 12/54 (22%)
Query: 406 NVCDNELLHCQNGGTCHN---NVRCLCPAAYTGILCEKL-------RCEEAGSC 449
N CD++ C +GGTC + + RC CP YTG C+ L C+ G C
Sbjct: 1023 NECDSQ--PCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKC 1074
Score = 37.7 bits (86), Expect = 0.023
Identities = 18/44 (40%), Positives = 25/44 (56%), Gaps = 7/44 (15%)
Query: 408 CDNELLHCQNGGTC---HNNVRCLCPAAYTGILCE--KLRCEEA 446
CD+ C+NGG C H RC CP+ +TG+ C+ + CE A
Sbjct: 1063 CDSS--PCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVA 1104
Score = 37.7 bits (86), Expect = 0.023
Identities = 39/165 (23%), Positives = 52/165 (31%), Gaps = 27/165 (16%)
Query: 306 CVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTAN------------- 352
CV + CEC TG C +G+P G + TA
Sbjct: 1284 CVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGA 1343
Query: 353 TCIPSISSIGNPPKFNRIWPNISSLEVSNPKQVAPKLALSTVSSVQVANHKRANVCDNEL 412
TC + G+ N +S P+ L L + + +
Sbjct: 1344 TCENDARTCGSLRCLN------GGTCISGPRSPTC-LCLGPFTGPECQFPASSPCLGGN- 1395
Query: 413 LHCQNGGTCHNN-----VRCLCPAAYTGILCEKLRCEEAGSCGSD 452
C N GTC RCLCPA + G+LC L G G D
Sbjct: 1396 -PCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGRD 1439
Score = 37.4 bits (85), Expect = 0.030
Identities = 40/161 (24%), Positives = 54/161 (33%), Gaps = 28/161 (17%)
Query: 295 GRCKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTC 354
G C+ H C + C C TGP+C RP+ P S P P TC
Sbjct: 187 GLCR---HGGTCHNEVGSYRCVCRATHTGPNCE--------RPYVPCS--PSPCQNGGTC 233
Query: 355 IPS---ISSIGNPPKFN--RIWPNISSLEVSNPKQVAPKLALSTVSSVQVANHKRANVCD 409
P+ P F NI +N K + + + C
Sbjct: 234 RPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCT 293
Query: 410 NELLHCQ-------NGGTCHN---NVRCLCPAAYTGILCEK 440
++ CQ NGGTCHN C+C +TG C +
Sbjct: 294 EDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSE 334
Score = 35.4 bits (80), Expect = 0.12
Identities = 21/63 (33%), Positives = 25/63 (39%), Gaps = 10/63 (15%)
Query: 402 HKRANVCDNELLHCQNGGTCH---NNVRCLCPAAYTGIL-------CEKLRCEEAGSCGS 451
H N D C NGGTC N+ CLCP +TG C+ C G+C
Sbjct: 979 HCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQD 1038
Query: 452 DSG 454
G
Sbjct: 1039 GCG 1041
Score = 34.3 bits (77), Expect = 0.26
Identities = 19/60 (31%), Positives = 26/60 (43%), Gaps = 9/60 (15%)
Query: 406 NVCDNELLHCQNGGTCHNNVR---CLCPAAYTGILCE------KLRCEEAGSCGSDSGQG 456
N+ D C +G TCH+ V C CP TG+LC C E +C ++ G
Sbjct: 335 NIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNG 394
Score = 33.9 bits (76), Expect = 0.34
Identities = 14/28 (50%), Positives = 16/28 (57%), Gaps = 3/28 (10%)
Query: 415 CQNGGTC---HNNVRCLCPAAYTGILCE 439
CQNGGTC N +C CP G+ CE
Sbjct: 1192 CQNGGTCLDLPNTYKCSCPRGTQGVHCE 1219
Score = 33.1 bits (74), Expect = 0.57
Identities = 17/45 (37%), Positives = 20/45 (44%), Gaps = 10/45 (22%)
Query: 415 CQNGGTC---HNNVRCLCPAAYTGILCEKL-------RCEEAGSC 449
CQ+GG C N C C A YTG CE L C+ +C
Sbjct: 1116 CQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATC 1160
Score = 32.0 bits (71), Expect = 1.3
Identities = 39/161 (24%), Positives = 58/161 (36%), Gaps = 41/161 (25%)
Query: 302 HATVCVYDNSKLTCECEHNTTGPDC--------GKCKK--NYQGRPWSPGSYLPIPKG-T 350
H C + CEC H TG C C + N P + + P G T
Sbjct: 346 HGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYT 405
Query: 351 ANTCIPSIS--SIGNPPKFNRIWPNISSLEVSNPKQVAPKLALSTVSS-----VQVANHK 403
C + S+G +NP + A K ++T+ S +Q
Sbjct: 406 GPACSQDVDECSLG-----------------ANPCEHAGK-CINTLGSFECQCLQGYTGP 447
Query: 404 RANVCDNELLH--CQNGGTCHNNV---RCLCPAAYTGILCE 439
R + NE + CQN TC + + +C+C Y G+ CE
Sbjct: 448 RCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCE 488
Score = 32.0 bits (71), Expect = 1.3
Identities = 16/45 (35%), Positives = 22/45 (48%), Gaps = 10/45 (22%)
Query: 415 CQNGGTCHNNV---RCLCPAAYTGILCE-------KLRCEEAGSC 449
C+NG C + V C CPA ++GI CE + C G+C
Sbjct: 954 CRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTC 998
Score = 31.2 bits (69), Expect = 2.2
Identities = 18/57 (31%), Positives = 26/57 (45%), Gaps = 4/57 (7%)
Query: 401 NHKRANVCDNELLHCQNGGTCH---NNVRCLCPAAYTGILCEKLRCEEAGSCGSDSG 454
+H N+ + C++GGTC N C C TG CE + ++ S DSG
Sbjct: 598 HHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCE-INLDDCASSPCDSG 653
Score = 31.2 bits (69), Expect = 2.2
Identities = 16/45 (35%), Positives = 20/45 (44%), Gaps = 10/45 (22%)
Query: 415 CQNGGTC---HNNVRCLCPAAYTGILCE-------KLRCEEAGSC 449
C++G +C H RC C A Y+G CE C GSC
Sbjct: 878 CRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSC 922
Score = 30.8 bits (68), Expect = 2.8
Identities = 14/45 (31%), Positives = 20/45 (44%), Gaps = 10/45 (22%)
Query: 415 CQNGGTCH----NNVRCLCPAAYTGILCEKL------RCEEAGSC 449
C+NGGTC +C CP ++G C++ C G C
Sbjct: 111 CRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQC 155
Score = 30.4 bits (67), Expect = 3.7
Identities = 16/49 (32%), Positives = 18/49 (36%), Gaps = 14/49 (28%)
Query: 415 CQNGGTCHNN-----VRCLCPAAYTGILCEK---------LRCEEAGSC 449
C G C N C CP+ YTG C + CE AG C
Sbjct: 381 CNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKC 429
Score = 29.6 bits (65), Expect = 6.3
Identities = 15/41 (36%), Positives = 16/41 (39%), Gaps = 7/41 (17%)
Query: 415 CQNGGTCH---NNVRCLCPAAYTGILCEKLRCEEAGSCGSD 452
C NGGTC N C CP Y C E C S+
Sbjct: 687 CHNGGTCEDGINGFTCRCPEGYHDPTC----LSEVNECNSN 723
Score = 29.6 bits (65), Expect = 6.3
Identities = 16/45 (35%), Positives = 20/45 (44%), Gaps = 10/45 (22%)
Query: 415 CQNGGTCHNNV---RCLCPAAYTGILCEKL-------RCEEAGSC 449
C N GTC ++V +C C YTG CE + C G C
Sbjct: 800 CLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGEC 844
Score = 29.6 bits (65), Expect = 6.3
Identities = 15/52 (28%), Positives = 21/52 (40%), Gaps = 12/52 (23%)
Query: 415 CQNGGTC-----HNNVRCLCPAAYTGILCE-------KLRCEEAGSCGSDSG 454
C+NGG C + + C+CP + G CE C SC + G
Sbjct: 838 CRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHG 889
>gi|55770876 notch4 preproprotein [Homo sapiens]
Length = 2003
Score = 42.4 bits (98), Expect = 0.001
Identities = 42/154 (27%), Positives = 53/154 (34%), Gaps = 25/154 (16%)
Query: 302 HATVCVYDNSKLTCECEHNTTGPDC---------GKCKKNYQGRPWSPGSYLPI--PKGT 350
H C S C C TGP C G C P SPG Y P T
Sbjct: 702 HGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNP-SPGGYYCTCPPSHT 760
Query: 351 ANTCIPSISSIGNPPKFNRIWPNISSLEVSNPKQVAPKLALSTVSSVQVANHKRANVCDN 410
C S + P FN V+ P + A+ + R + D+
Sbjct: 761 GPQCQTSTDYCVSAPCFN------GGTCVNRPGTFSCLCAMG-FQGPRCEGKLRPSCADS 813
Query: 411 ELLHCQNGGTCHNNV---RCLCPAAYTGILCEKL 441
C+N TC ++ RCLCP YTG C+ L
Sbjct: 814 P---CRNRATCQDSPQGPRCLCPTGYTGGSCQTL 844
Score = 38.1 bits (87), Expect = 0.018
Identities = 21/60 (35%), Positives = 29/60 (48%), Gaps = 14/60 (23%)
Query: 409 DNELLH-CQNGGTCHNNV---RCLCPAAYTGILCEK----------LRCEEAGSCGSDSG 454
DN + H CQNGGTC + + CLCP +TG C + C G+C + +G
Sbjct: 278 DNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAG 337
Score = 37.0 bits (84), Expect = 0.040
Identities = 48/182 (26%), Positives = 59/182 (32%), Gaps = 43/182 (23%)
Query: 299 CNLHATVCVYDNSKLTCECEHNTTGPDC---------GKCKKNYQGRPWSPGSYLPIPKG 349
C H C + +C C+ TGP+C C P G P G
Sbjct: 665 CTCHHGHC----QRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTG 720
Query: 350 -TANTCIPSISSIGNPPKFNRIWPNISS---LEVSNPKQVAPKLALSTVSSVQVANHKRA 405
T TC +++ + P N N S P P+ ST V
Sbjct: 721 YTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAP----- 775
Query: 406 NVCDNELLHCQNGGTCHN---NVRCLCPAAYTGILCE-KLR-------CEEAGSCGSDSG 454
C NGGTC N CLC + G CE KLR C +C DS
Sbjct: 776 ---------CFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATC-QDSP 825
Query: 455 QG 456
QG
Sbjct: 826 QG 827
Score = 35.0 bits (79), Expect = 0.15
Identities = 13/30 (43%), Positives = 19/30 (63%), Gaps = 3/30 (10%)
Query: 414 HCQNGGTCHNNV---RCLCPAAYTGILCEK 440
HC+NGGTC N+ C+C + + G CE+
Sbjct: 325 HCRNGGTCQNSAGSFHCVCVSGWGGTSCEE 354
Score = 35.0 bits (79), Expect = 0.15
Identities = 14/28 (50%), Positives = 18/28 (64%), Gaps = 3/28 (10%)
Query: 415 CQNGGTCHN---NVRCLCPAAYTGILCE 439
C++GG+C N + CLCP YTG CE
Sbjct: 446 CEHGGSCLNTPGSFNCLCPPGYTGSRCE 473
Score = 34.3 bits (77), Expect = 0.26
Identities = 40/164 (24%), Positives = 56/164 (34%), Gaps = 15/164 (9%)
Query: 288 ISDIKVRGRCKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIP 347
+ D+ + C N H C+ C C TGP C + Q S G +
Sbjct: 844 LMDLCAQKPCPRNSH---CLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSL 900
Query: 348 KGTANTCIPSISSI--GNPPKF--NRIWPNISSLEVSNPKQVAPKLALSTVSSVQVANHK 403
C+ S S PP F + +++ E + A +A + Q A
Sbjct: 901 CHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGY 960
Query: 404 RANVCDNELLHCQ-----NGGTCH---NNVRCLCPAAYTGILCE 439
C EL CQ N GTC C CP + G+ CE
Sbjct: 961 DGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCE 1004
Score = 32.7 bits (73), Expect = 0.75
Identities = 20/61 (32%), Positives = 26/61 (42%), Gaps = 12/61 (19%)
Query: 400 ANHKRANVCDNELLHCQNGGTCHNNV---RCLCPAAYTGILCEKLR--------CEEAGS 448
A + N C + C G +CHN + +CLCP G CE LR C G+
Sbjct: 190 ACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCE-LRAGPCPPRGCSNGGT 248
Query: 449 C 449
C
Sbjct: 249 C 249
Score = 31.2 bits (69), Expect = 2.2
Identities = 14/43 (32%), Positives = 20/43 (46%), Gaps = 7/43 (16%)
Query: 415 CQNGGTC---HNNVRCLCPAAYTGILCEKLRCEEAGSCGSDSG 454
C NGG C + ++C CP + G CE+ + C D G
Sbjct: 165 CVNGGVCLATYPQIQCHCPPGFEGHACER----DVNECFQDPG 203
Score = 30.8 bits (68), Expect = 2.8
Identities = 42/174 (24%), Positives = 61/174 (35%), Gaps = 53/174 (30%)
Query: 292 KVRGRCKCN--LHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKG 349
++R C N ++ VC+ ++ C C G C+++ PG P PKG
Sbjct: 155 QLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGH---ACERDVNECFQDPG---PCPKG 208
Query: 350 TANTCIPSISSIGNPPKFNRIWPNISSLEVSNPKQVAPKLALSTVSSVQVANHKRANVCD 409
T+ C ++ S F + P Q P+ L RA C
Sbjct: 209 TS--CHNTLGS------FQCLCP---------VGQEGPRCEL------------RAGPCP 239
Query: 410 NELLHCQNGGTCHNNVR-------CLCPAAYTGILCE-------KLRCEEAGSC 449
C NGGTC CLCP + G CE +C+ G+C
Sbjct: 240 PR--GCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTC 291
Score = 29.6 bits (65), Expect = 6.3
Identities = 13/27 (48%), Positives = 15/27 (55%), Gaps = 3/27 (11%)
Query: 415 CQNGGTCHNNV---RCLCPAAYTGILC 438
C G TC + V CLCP TG+LC
Sbjct: 364 CAPGSTCIDRVGSFSCLCPPGRTGLLC 390
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.441
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,924,164
Number of Sequences: 37866
Number of extensions: 1106972
Number of successful extensions: 3511
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 74
Number of HSP's successfully gapped in prelim test: 96
Number of HSP's that attempted gapping in prelim test: 2514
Number of HSP's gapped (non-prelim): 948
length of query: 480
length of database: 18,247,518
effective HSP length: 106
effective length of query: 374
effective length of database: 14,233,722
effective search space: 5323412028
effective search space used: 5323412028
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.