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Search of human proteins with 163644261
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|163644261 hypothetical protein LOC283638 isoform 1 [Homo
sapiens]
(1554 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|163644261 hypothetical protein LOC283638 isoform 1 [Homo sapi... 3121 0.0
gi|61742808 hypothetical protein LOC283638 isoform 2 [Homo sapiens] 2979 0.0
gi|109255228 centrosomal protein 170kDa isoform alpha [Homo sapi... 659 0.0
gi|109255230 centrosomal protein 170kDa isoform beta [Homo sapiens] 347 4e-95
gi|109255232 centrosomal protein 170kDa isoform gamma [Homo sapi... 347 4e-95
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 76 2e-13
gi|56676397 ankyrin repeat domain 11 [Homo sapiens] 68 8e-11
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 65 5e-10
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 65 5e-10
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 63 2e-09
gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens] 63 2e-09
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 62 4e-09
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 62 4e-09
gi|166706868 synaptopodin 2-like isoform a [Homo sapiens] 62 6e-09
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 61 1e-08
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] 59 5e-08
gi|50301232 synaptopodin 2-like isoform b [Homo sapiens] 59 5e-08
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 57 1e-07
gi|21314720 Smad nuclear interacting protein [Homo sapiens] 57 1e-07
gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ... 57 1e-07
gi|18079216 CASK interacting protein 1 [Homo sapiens] 57 2e-07
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 57 2e-07
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 57 2e-07
gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ... 56 3e-07
gi|178557734 microtubule-associated protein tau isoform 6 [Homo ... 55 4e-07
gi|73476377 LBXCOR1 homolog [Homo sapiens] 55 4e-07
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 55 5e-07
gi|157785645 SPEG complex locus [Homo sapiens] 55 7e-07
gi|116268127 kinase non-catalytic C-lobe domain (KIND) containin... 55 7e-07
gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens] 54 9e-07
>gi|163644261 hypothetical protein LOC283638 isoform 1 [Homo sapiens]
Length = 1554
Score = 3121 bits (8091), Expect = 0.0
Identities = 1554/1554 (100%), Positives = 1554/1554 (100%)
Query: 1 MSATSWFLVSSSGARHRLPRELIFVGREECELMLQSRSVDKQHAVINYDQDRDEHWVKDL 60
MSATSWFLVSSSGARHRLPRELIFVGREECELMLQSRSVDKQHAVINYDQDRDEHWVKDL
Sbjct: 1 MSATSWFLVSSSGARHRLPRELIFVGREECELMLQSRSVDKQHAVINYDQDRDEHWVKDL 60
Query: 61 GSLNGTFVNDMRIPDQKYVTLKLNDVIRFGYDSNMYVLERVQHRVPEEALKHEKYTSQLQ 120
GSLNGTFVNDMRIPDQKYVTLKLNDVIRFGYDSNMYVLERVQHRVPEEALKHEKYTSQLQ
Sbjct: 61 GSLNGTFVNDMRIPDQKYVTLKLNDVIRFGYDSNMYVLERVQHRVPEEALKHEKYTSQLQ 120
Query: 121 VSVKGLAPKRSEALPEHTPYCEASNPRPEKGDRRPGTEAASYRTPLYGQPSWWGEDDGST 180
VSVKGLAPKRSEALPEHTPYCEASNPRPEKGDRRPGTEAASYRTPLYGQPSWWGEDDGST
Sbjct: 121 VSVKGLAPKRSEALPEHTPYCEASNPRPEKGDRRPGTEAASYRTPLYGQPSWWGEDDGST 180
Query: 181 LPDAQRQGEPYPERPKGPVQQDGELHGFRAPAEPQGCSFRREPSYFEIPTKETPQPSQPP 240
LPDAQRQGEPYPERPKGPVQQDGELHGFRAPAEPQGCSFRREPSYFEIPTKETPQPSQPP
Sbjct: 181 LPDAQRQGEPYPERPKGPVQQDGELHGFRAPAEPQGCSFRREPSYFEIPTKETPQPSQPP 240
Query: 241 EVPAHEMPTKDAEAGGGGAAPVVQSHASFTIEFDDCSPGKMKIKDHITKFSLRQRRPPGK 300
EVPAHEMPTKDAEAGGGGAAPVVQSHASFTIEFDDCSPGKMKIKDHITKFSLRQRRPPGK
Sbjct: 241 EVPAHEMPTKDAEAGGGGAAPVVQSHASFTIEFDDCSPGKMKIKDHITKFSLRQRRPPGK 300
Query: 301 EATPGEMVSAETKVADWLVQNDPSLLHRVGPGDDRHSTKSDLPVHTRTLKGHKHEDGTQS 360
EATPGEMVSAETKVADWLVQNDPSLLHRVGPGDDRHSTKSDLPVHTRTLKGHKHEDGTQS
Sbjct: 301 EATPGEMVSAETKVADWLVQNDPSLLHRVGPGDDRHSTKSDLPVHTRTLKGHKHEDGTQS 360
Query: 361 DSEDPLAKAASAAGVPLEASGEQVRLQRQIKRDPQELLHNQQAFVIEFFDEDTPRKKRSQ 420
DSEDPLAKAASAAGVPLEASGEQVRLQRQIKRDPQELLHNQQAFVIEFFDEDTPRKKRSQ
Sbjct: 361 DSEDPLAKAASAAGVPLEASGEQVRLQRQIKRDPQELLHNQQAFVIEFFDEDTPRKKRSQ 420
Query: 421 SFTHSPSGDPKADKRRGPTPADRDRPSVPAPVQAGGRSSGPQRAGSLKREKTEERLGSPS 480
SFTHSPSGDPKADKRRGPTPADRDRPSVPAPVQAGGRSSGPQRAGSLKREKTEERLGSPS
Sbjct: 421 SFTHSPSGDPKADKRRGPTPADRDRPSVPAPVQAGGRSSGPQRAGSLKREKTEERLGSPS 480
Query: 481 PASRTPARPFGSVGRRSRLAQDFMAQCLRESSPAARPSPEKVPPVLPAPLTPHGTSPVGP 540
PASRTPARPFGSVGRRSRLAQDFMAQCLRESSPAARPSPEKVPPVLPAPLTPHGTSPVGP
Sbjct: 481 PASRTPARPFGSVGRRSRLAQDFMAQCLRESSPAARPSPEKVPPVLPAPLTPHGTSPVGP 540
Query: 541 PTPPPAPTDPQLTKARKQEEDDSLSDAGTYTIETEAQDTEVEEARKMIDQVFGVLESPEL 600
PTPPPAPTDPQLTKARKQEEDDSLSDAGTYTIETEAQDTEVEEARKMIDQVFGVLESPEL
Sbjct: 541 PTPPPAPTDPQLTKARKQEEDDSLSDAGTYTIETEAQDTEVEEARKMIDQVFGVLESPEL 600
Query: 601 SRASSATFRPVIRGDRDESDDGGVAQRMALLQEFASRPLGAAPQAEHQGLPVPGSPGGQK 660
SRASSATFRPVIRGDRDESDDGGVAQRMALLQEFASRPLGAAPQAEHQGLPVPGSPGGQK
Sbjct: 601 SRASSATFRPVIRGDRDESDDGGVAQRMALLQEFASRPLGAAPQAEHQGLPVPGSPGGQK 660
Query: 661 WVSRWASLADSYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERADSPAGPESSRR 720
WVSRWASLADSYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERADSPAGPESSRR
Sbjct: 661 WVSRWASLADSYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERADSPAGPESSRR 720
Query: 721 SGPGPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQEGPTWS 780
SGPGPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQEGPTWS
Sbjct: 721 SGPGPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQEGPTWS 780
Query: 781 RGRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSA 840
RGRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSA
Sbjct: 781 RGRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSA 840
Query: 841 NGRMVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSHPLLQDLAATRA 900
NGRMVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSHPLLQDLAATRA
Sbjct: 841 NGRMVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSHPLLQDLAATRA 900
Query: 901 ARMDFHSQDTHLILKETETALAALEARLLSNSVDAECEGGSTPRPPEDALSGDSDVDTAS 960
ARMDFHSQDTHLILKETETALAALEARLLSNSVDAECEGGSTPRPPEDALSGDSDVDTAS
Sbjct: 901 ARMDFHSQDTHLILKETETALAALEARLLSNSVDAECEGGSTPRPPEDALSGDSDVDTAS 960
Query: 961 TVSLRSGKSGPSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAREQSSERQHHPLGPTDM 1020
TVSLRSGKSGPSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAREQSSERQHHPLGPTDM
Sbjct: 961 TVSLRSGKSGPSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAREQSSERQHHPLGPTDM 1020
Query: 1021 GRGEPVRRSAIRRGHRPRGSLDWPSEERGPVLAHLPSSDVMASNHETPEATGAGRLGSRR 1080
GRGEPVRRSAIRRGHRPRGSLDWPSEERGPVLAHLPSSDVMASNHETPEATGAGRLGSRR
Sbjct: 1021 GRGEPVRRSAIRRGHRPRGSLDWPSEERGPVLAHLPSSDVMASNHETPEATGAGRLGSRR 1080
Query: 1081 KPAAPPPSPAAREEQSRSSASSQKGPQALTRSNSLSTPRPTRASRLRRARLGDASDTEAA 1140
KPAAPPPSPAAREEQSRSSASSQKGPQALTRSNSLSTPRPTRASRLRRARLGDASDTEAA
Sbjct: 1081 KPAAPPPSPAAREEQSRSSASSQKGPQALTRSNSLSTPRPTRASRLRRARLGDASDTEAA 1140
Query: 1141 DGERGSLGNPEPVGRPAAEQAKKLSRLDILAMPRKRAGSFTGTSDPEAAPARTSFSGRSV 1200
DGERGSLGNPEPVGRPAAEQAKKLSRLDILAMPRKRAGSFTGTSDPEAAPARTSFSGRSV
Sbjct: 1141 DGERGSLGNPEPVGRPAAEQAKKLSRLDILAMPRKRAGSFTGTSDPEAAPARTSFSGRSV 1200
Query: 1201 ELCCASRKPTMAEARAVSRKAANTATTTGPRQPFSRARSGSARYTSTTQTPRAGSSSRAR 1260
ELCCASRKPTMAEARAVSRKAANTATTTGPRQPFSRARSGSARYTSTTQTPRAGSSSRAR
Sbjct: 1201 ELCCASRKPTMAEARAVSRKAANTATTTGPRQPFSRARSGSARYTSTTQTPRAGSSSRAR 1260
Query: 1261 SRAPGPRDTDDDEEEPDPYGFIVQTAEIAEIARLSQTLVKDVAILAQEIHDVAGDGDTLG 1320
SRAPGPRDTDDDEEEPDPYGFIVQTAEIAEIARLSQTLVKDVAILAQEIHDVAGDGDTLG
Sbjct: 1261 SRAPGPRDTDDDEEEPDPYGFIVQTAEIAEIARLSQTLVKDVAILAQEIHDVAGDGDTLG 1320
Query: 1321 SSEPAHSASLSNMPSTPASTISAREELVQRIPEASLNFQKVPPGSLNSRDFDQNMNDSCE 1380
SSEPAHSASLSNMPSTPASTISAREELVQRIPEASLNFQKVPPGSLNSRDFDQNMNDSCE
Sbjct: 1321 SSEPAHSASLSNMPSTPASTISAREELVQRIPEASLNFQKVPPGSLNSRDFDQNMNDSCE 1380
Query: 1381 DALANKTRPRNREEVIFDNLMLNPVSQLSQAIRENTEHLAEKMKILFQNTGRAWEDLEAR 1440
DALANKTRPRNREEVIFDNLMLNPVSQLSQAIRENTEHLAEKMKILFQNTGRAWEDLEAR
Sbjct: 1381 DALANKTRPRNREEVIFDNLMLNPVSQLSQAIRENTEHLAEKMKILFQNTGRAWEDLEAR 1440
Query: 1441 INAENEVPILKTSNKEISSILKELRRVQKQLEVINAIVDPSGSLDLLTGNRSLASSAQPG 1500
INAENEVPILKTSNKEISSILKELRRVQKQLEVINAIVDPSGSLDLLTGNRSLASSAQPG
Sbjct: 1441 INAENEVPILKTSNKEISSILKELRRVQKQLEVINAIVDPSGSLDLLTGNRSLASSAQPG 1500
Query: 1501 LGKGRVAAQSPPSPASAEALLPALPLRNFPQRASCGPPSLPDPTFLPDAERFLI 1554
LGKGRVAAQSPPSPASAEALLPALPLRNFPQRASCGPPSLPDPTFLPDAERFLI
Sbjct: 1501 LGKGRVAAQSPPSPASAEALLPALPLRNFPQRASCGPPSLPDPTFLPDAERFLI 1554
>gi|61742808 hypothetical protein LOC283638 isoform 2 [Homo sapiens]
Length = 1484
Score = 2979 bits (7722), Expect = 0.0
Identities = 1484/1484 (100%), Positives = 1484/1484 (100%)
Query: 71 MRIPDQKYVTLKLNDVIRFGYDSNMYVLERVQHRVPEEALKHEKYTSQLQVSVKGLAPKR 130
MRIPDQKYVTLKLNDVIRFGYDSNMYVLERVQHRVPEEALKHEKYTSQLQVSVKGLAPKR
Sbjct: 1 MRIPDQKYVTLKLNDVIRFGYDSNMYVLERVQHRVPEEALKHEKYTSQLQVSVKGLAPKR 60
Query: 131 SEALPEHTPYCEASNPRPEKGDRRPGTEAASYRTPLYGQPSWWGEDDGSTLPDAQRQGEP 190
SEALPEHTPYCEASNPRPEKGDRRPGTEAASYRTPLYGQPSWWGEDDGSTLPDAQRQGEP
Sbjct: 61 SEALPEHTPYCEASNPRPEKGDRRPGTEAASYRTPLYGQPSWWGEDDGSTLPDAQRQGEP 120
Query: 191 YPERPKGPVQQDGELHGFRAPAEPQGCSFRREPSYFEIPTKETPQPSQPPEVPAHEMPTK 250
YPERPKGPVQQDGELHGFRAPAEPQGCSFRREPSYFEIPTKETPQPSQPPEVPAHEMPTK
Sbjct: 121 YPERPKGPVQQDGELHGFRAPAEPQGCSFRREPSYFEIPTKETPQPSQPPEVPAHEMPTK 180
Query: 251 DAEAGGGGAAPVVQSHASFTIEFDDCSPGKMKIKDHITKFSLRQRRPPGKEATPGEMVSA 310
DAEAGGGGAAPVVQSHASFTIEFDDCSPGKMKIKDHITKFSLRQRRPPGKEATPGEMVSA
Sbjct: 181 DAEAGGGGAAPVVQSHASFTIEFDDCSPGKMKIKDHITKFSLRQRRPPGKEATPGEMVSA 240
Query: 311 ETKVADWLVQNDPSLLHRVGPGDDRHSTKSDLPVHTRTLKGHKHEDGTQSDSEDPLAKAA 370
ETKVADWLVQNDPSLLHRVGPGDDRHSTKSDLPVHTRTLKGHKHEDGTQSDSEDPLAKAA
Sbjct: 241 ETKVADWLVQNDPSLLHRVGPGDDRHSTKSDLPVHTRTLKGHKHEDGTQSDSEDPLAKAA 300
Query: 371 SAAGVPLEASGEQVRLQRQIKRDPQELLHNQQAFVIEFFDEDTPRKKRSQSFTHSPSGDP 430
SAAGVPLEASGEQVRLQRQIKRDPQELLHNQQAFVIEFFDEDTPRKKRSQSFTHSPSGDP
Sbjct: 301 SAAGVPLEASGEQVRLQRQIKRDPQELLHNQQAFVIEFFDEDTPRKKRSQSFTHSPSGDP 360
Query: 431 KADKRRGPTPADRDRPSVPAPVQAGGRSSGPQRAGSLKREKTEERLGSPSPASRTPARPF 490
KADKRRGPTPADRDRPSVPAPVQAGGRSSGPQRAGSLKREKTEERLGSPSPASRTPARPF
Sbjct: 361 KADKRRGPTPADRDRPSVPAPVQAGGRSSGPQRAGSLKREKTEERLGSPSPASRTPARPF 420
Query: 491 GSVGRRSRLAQDFMAQCLRESSPAARPSPEKVPPVLPAPLTPHGTSPVGPPTPPPAPTDP 550
GSVGRRSRLAQDFMAQCLRESSPAARPSPEKVPPVLPAPLTPHGTSPVGPPTPPPAPTDP
Sbjct: 421 GSVGRRSRLAQDFMAQCLRESSPAARPSPEKVPPVLPAPLTPHGTSPVGPPTPPPAPTDP 480
Query: 551 QLTKARKQEEDDSLSDAGTYTIETEAQDTEVEEARKMIDQVFGVLESPELSRASSATFRP 610
QLTKARKQEEDDSLSDAGTYTIETEAQDTEVEEARKMIDQVFGVLESPELSRASSATFRP
Sbjct: 481 QLTKARKQEEDDSLSDAGTYTIETEAQDTEVEEARKMIDQVFGVLESPELSRASSATFRP 540
Query: 611 VIRGDRDESDDGGVAQRMALLQEFASRPLGAAPQAEHQGLPVPGSPGGQKWVSRWASLAD 670
VIRGDRDESDDGGVAQRMALLQEFASRPLGAAPQAEHQGLPVPGSPGGQKWVSRWASLAD
Sbjct: 541 VIRGDRDESDDGGVAQRMALLQEFASRPLGAAPQAEHQGLPVPGSPGGQKWVSRWASLAD 600
Query: 671 SYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERADSPAGPESSRRSGPGPPELDS 730
SYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERADSPAGPESSRRSGPGPPELDS
Sbjct: 601 SYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERADSPAGPESSRRSGPGPPELDS 660
Query: 731 EQPSRLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQEGPTWSRGRRSPRAPG 790
EQPSRLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQEGPTWSRGRRSPRAPG
Sbjct: 661 EQPSRLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQEGPTWSRGRRSPRAPG 720
Query: 791 EPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSANGRMVIQLRP 850
EPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSANGRMVIQLRP
Sbjct: 721 EPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSANGRMVIQLRP 780
Query: 851 GRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSHPLLQDLAATRAARMDFHSQDT 910
GRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSHPLLQDLAATRAARMDFHSQDT
Sbjct: 781 GRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSHPLLQDLAATRAARMDFHSQDT 840
Query: 911 HLILKETETALAALEARLLSNSVDAECEGGSTPRPPEDALSGDSDVDTASTVSLRSGKSG 970
HLILKETETALAALEARLLSNSVDAECEGGSTPRPPEDALSGDSDVDTASTVSLRSGKSG
Sbjct: 841 HLILKETETALAALEARLLSNSVDAECEGGSTPRPPEDALSGDSDVDTASTVSLRSGKSG 900
Query: 971 PSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAREQSSERQHHPLGPTDMGRGEPVRRSA 1030
PSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAREQSSERQHHPLGPTDMGRGEPVRRSA
Sbjct: 901 PSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAREQSSERQHHPLGPTDMGRGEPVRRSA 960
Query: 1031 IRRGHRPRGSLDWPSEERGPVLAHLPSSDVMASNHETPEATGAGRLGSRRKPAAPPPSPA 1090
IRRGHRPRGSLDWPSEERGPVLAHLPSSDVMASNHETPEATGAGRLGSRRKPAAPPPSPA
Sbjct: 961 IRRGHRPRGSLDWPSEERGPVLAHLPSSDVMASNHETPEATGAGRLGSRRKPAAPPPSPA 1020
Query: 1091 AREEQSRSSASSQKGPQALTRSNSLSTPRPTRASRLRRARLGDASDTEAADGERGSLGNP 1150
AREEQSRSSASSQKGPQALTRSNSLSTPRPTRASRLRRARLGDASDTEAADGERGSLGNP
Sbjct: 1021 AREEQSRSSASSQKGPQALTRSNSLSTPRPTRASRLRRARLGDASDTEAADGERGSLGNP 1080
Query: 1151 EPVGRPAAEQAKKLSRLDILAMPRKRAGSFTGTSDPEAAPARTSFSGRSVELCCASRKPT 1210
EPVGRPAAEQAKKLSRLDILAMPRKRAGSFTGTSDPEAAPARTSFSGRSVELCCASRKPT
Sbjct: 1081 EPVGRPAAEQAKKLSRLDILAMPRKRAGSFTGTSDPEAAPARTSFSGRSVELCCASRKPT 1140
Query: 1211 MAEARAVSRKAANTATTTGPRQPFSRARSGSARYTSTTQTPRAGSSSRARSRAPGPRDTD 1270
MAEARAVSRKAANTATTTGPRQPFSRARSGSARYTSTTQTPRAGSSSRARSRAPGPRDTD
Sbjct: 1141 MAEARAVSRKAANTATTTGPRQPFSRARSGSARYTSTTQTPRAGSSSRARSRAPGPRDTD 1200
Query: 1271 DDEEEPDPYGFIVQTAEIAEIARLSQTLVKDVAILAQEIHDVAGDGDTLGSSEPAHSASL 1330
DDEEEPDPYGFIVQTAEIAEIARLSQTLVKDVAILAQEIHDVAGDGDTLGSSEPAHSASL
Sbjct: 1201 DDEEEPDPYGFIVQTAEIAEIARLSQTLVKDVAILAQEIHDVAGDGDTLGSSEPAHSASL 1260
Query: 1331 SNMPSTPASTISAREELVQRIPEASLNFQKVPPGSLNSRDFDQNMNDSCEDALANKTRPR 1390
SNMPSTPASTISAREELVQRIPEASLNFQKVPPGSLNSRDFDQNMNDSCEDALANKTRPR
Sbjct: 1261 SNMPSTPASTISAREELVQRIPEASLNFQKVPPGSLNSRDFDQNMNDSCEDALANKTRPR 1320
Query: 1391 NREEVIFDNLMLNPVSQLSQAIRENTEHLAEKMKILFQNTGRAWEDLEARINAENEVPIL 1450
NREEVIFDNLMLNPVSQLSQAIRENTEHLAEKMKILFQNTGRAWEDLEARINAENEVPIL
Sbjct: 1321 NREEVIFDNLMLNPVSQLSQAIRENTEHLAEKMKILFQNTGRAWEDLEARINAENEVPIL 1380
Query: 1451 KTSNKEISSILKELRRVQKQLEVINAIVDPSGSLDLLTGNRSLASSAQPGLGKGRVAAQS 1510
KTSNKEISSILKELRRVQKQLEVINAIVDPSGSLDLLTGNRSLASSAQPGLGKGRVAAQS
Sbjct: 1381 KTSNKEISSILKELRRVQKQLEVINAIVDPSGSLDLLTGNRSLASSAQPGLGKGRVAAQS 1440
Query: 1511 PPSPASAEALLPALPLRNFPQRASCGPPSLPDPTFLPDAERFLI 1554
PPSPASAEALLPALPLRNFPQRASCGPPSLPDPTFLPDAERFLI
Sbjct: 1441 PPSPASAEALLPALPLRNFPQRASCGPPSLPDPTFLPDAERFLI 1484
>gi|109255228 centrosomal protein 170kDa isoform alpha [Homo sapiens]
Length = 1584
Score = 659 bits (1701), Expect = 0.0
Identities = 555/1654 (33%), Positives = 807/1654 (48%), Gaps = 295/1654 (17%)
Query: 1 MSATSWFLVSSSGARHRLPRELIFVGREECELMLQSRSVDKQHAVINYDQDRDEHWVKDL 60
MS TSWFLVSS G RHRLPRE+IFVGR++CELMLQSRSVDKQHAVINYD DEH VKDL
Sbjct: 1 MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDL 60
Query: 61 GSLNGTFVNDMRIPDQKYVTLKLNDVIRFGYDSNMYVLERVQHRVPEEALKHEKYTSQLQ 120
GSLNGTFVND+RIP+Q Y+TLKL D +RFGYD+N++ + + + RVPEEALKHEK+T QLQ
Sbjct: 61 GSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQ 120
Query: 121 VSVKGLAPKRSEALPEHTPYCEASNPRPE---------KGDRRPGTEAASYR-TPLYGQP 170
+S K + S++ + + ++ E K + + +A R TPLYGQP
Sbjct: 121 LSQKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQP 180
Query: 171 SWWGEDDGSTLPDAQRQGEPYPERPKGPVQQDG----ELHGFRAPAEPQGC-SFRREPSY 225
SWWG+D+ + G+P + + G ++ A A + F REPSY
Sbjct: 181 SWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCGIDAKQVEEQSAAANEEVLFPFCREPSY 240
Query: 226 FEIPTKETPQPSQPPEVPAHEMPTKDAEAGGGGAAPVVQSHASFTIEFDDCSPGKMKIKD 285
FEIPTKE QPSQ E HE+PTKD + A HASFTIEFDD +PGK+ I+D
Sbjct: 241 FEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGA----GHASFTIEFDDSTPGKVTIRD 296
Query: 286 HITKFSLRQRRPPGKEATPGE---------MVSAETKVADWLVQNDPSLLHRVGPGDDRH 336
H+TKF+ QR K+++PG M++ E KVADWL QN+P + +D
Sbjct: 297 HVTKFTSDQRH-KSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSK 355
Query: 337 STKSDLPVHTRTLKGHKHEDGTQSDSEDPLAKAASAAGVPLEASGEQVRLQRQIKRDPQE 396
S KSD+PV+ + LKG+KH+DGTQSDSE+ AG S ++ L+ ++R E
Sbjct: 356 SIKSDVPVYLKRLKGNKHDDGTQSDSEN--------AGAHRRCS-KRATLEEHLRRHHSE 406
Query: 397 LLHNQQAFVIEFFDEDTPRKKRSQSFTHSPSGDPKADKRRGPTPADRDRPSVPAPVQAGG 456
Q+ E K + Q+ T S A R G VP
Sbjct: 407 HKKLQKVQATE--------KHQDQAVTSS------AHHRGG--------HGVP------- 437
Query: 457 RSSGPQRAGSLKREKTEERLGSPSPASRTPARPFGSVGRRSRLAQDFMAQCLRESSPAAR 516
G L ++K+EE S R GS+G R D M + + A
Sbjct: 438 -------HGKLLKQKSEEPSVSIPFLQTALLRSSGSLGHRPSQEMDKMLK-----NQATS 485
Query: 517 PSPEKVPPVLPAPLTPHGTSPVGPPTPPPAPTDPQLTKARKQEEDDSLSDAGTYTIETEA 576
+ EK + DD SD GTYTIE E
Sbjct: 486 ATSEK-------------------------------------DNDDDQSDKGTYTIELEN 508
Query: 577 QDTEVEEARKMIDQVFGVLESPELSRASSATFRPVI-RGDRDESDDGGVAQRMALLQEFA 635
++E EARKMID+VFGV ++ + + RPVI +D D ++ A+++E
Sbjct: 509 PNSEEVEARKMIDKVFGVDDNQDYN-------RPVINEKHKDLIKDWALSSAAAVMEE-- 559
Query: 636 SRPLGAAPQAEHQGLPVPGSPGGQKWVSRWASLADSY-------------------SDPG 676
+PL H S G ++WVS+WASLA ++ ++
Sbjct: 560 RKPL--TTSGFHHSEEGTSSSGSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETE 617
Query: 677 LTEDGLGRRGGEPEGSLP---VRMRRRLPQLPSER--ADSPAGPESSRRSGPGPPE---- 727
++E G+ R SL R RR LPQLP+E +S ++RS G +
Sbjct: 618 ISESGMTVRSTGSATSLASQGERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTEL 677
Query: 728 LDSEQPSRLFGQEELDPD-SLSDASGSDGGR---------------GPEPGVEPQDSRRR 771
+ E P++++ +++ D D LS + + G PG E ++ +
Sbjct: 678 QEKETPTQVYQKDKQDADRPLSKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKE 737
Query: 772 SPQEGPTWSR-GRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSP 830
+ T ++ ++ R + TP + +G R+ E Q +Q P
Sbjct: 738 TSLVKQTLAKLQQQEQREEAQWTPTKLSSKNVSGQTDKCRE--------ETFKQESQ--P 787
Query: 831 PARDGVYVSANGRMVIQLRPGR--------SPEPDG-----PAPAFLRQESFTKEPASGP 877
P ++ + ++ G V Q R S P G + + +RQ SFT E
Sbjct: 788 PEKNSGHSTSKGDRVAQSESKRRKAEEILKSQTPKGGDKKESSKSLVRQGSFTIE----K 843
Query: 878 PAPGKP----PHI----SSHPLLQDLAATRAARMDFHSQ--------DTHLILKETETAL 921
P+P P PHI SS P LA T A+R+ S+ DT LILK+TE +
Sbjct: 844 PSPNIPIELIPHINKQTSSTP--SSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVM 901
Query: 922 AALEARLL-SNSVDAECEGGSTPRPPED-ALSGDSDVDTASTVSLRSGKSGPSPTTPQP- 978
A LEA+L N D EG TP D ++S +SDVDTAST+SL +G++ T +
Sbjct: 902 AFLEAKLREDNKTD---EGPDTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKS 958
Query: 979 -LRAQKEMSPSPPAAQDPGGTALVSAREQSSERQHHPLGPTDMGRGEPVRRSAIRRGHRP 1037
K+ + ++D ++ ARE+ ++ TD+G R+ G
Sbjct: 959 FTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKS--RSTDVGSRADGRKFVQSSGRIR 1016
Query: 1038 RGSLDWPSEERGPVLAHLPSSDVMASNHETPEATGAGRLGSRRKPAAPPPSPAAREEQSR 1097
+ S+D +++ + H SD+M+S+ ET G R P + +
Sbjct: 1017 QPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHG-----RTPLTSADEHVHSKLEGS 1071
Query: 1098 SSASSQKGP---QALTRSNSLSTPRPTRASRLRRARLGDASDTEAADGERGSLG------ 1148
S+ P + ++S +L PRPTR S LRRARLG+ASD+E AD ++ S+
Sbjct: 1072 KVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELADADKASVASEVSTT 1131
Query: 1149 ---NPEPVGRPAAEQAKKLSRLDILAMPRK-RAGSFTGTSDPEAAPARTSFSGRSVE--- 1201
+ P GR + +SR+D+LA PR+ R GS + SD EA +R+S S R+ E
Sbjct: 1132 SSTSKPPTGR------RNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASSRTAEAII 1185
Query: 1202 -----LCCASRKPTMAEARAVSR----KAANTATTTGPRQPFSRARSGSARYTSTTQ--- 1249
L + + A ++SR K + + G SR R Y ST++
Sbjct: 1186 RSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASVNSRWRRFPTDYASTSEDEF 1245
Query: 1250 -------------TPRAGSSSRARSRAPG-PRDTDDDEEEPDPYGFIVQ-TAEIAEIARL 1294
T A ++R +S P + + +I TA EIAR+
Sbjct: 1246 GSNRNSPKHTRLRTSPALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAHREEIARI 1305
Query: 1295 SQTLVKDVAILAQEIHDVAGDGDTLGSSEPAHSASLSNMPSTPASTISAREELVQRIPEA 1354
SQ D+A++A+EI+DVAG+ D++ SS A S ++S +TP S I REELV R+ +
Sbjct: 1306 SQ----DLALIAREINDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDTREELVDRVFDE 1361
Query: 1355 SLNFQKVPP---------GSLNSRDFDQNMNDSCEDALANKTRPRNREEVIFDNLMLNPV 1405
SLNF+K+PP + S D + + + R +R+EV+ DNL+L+ V
Sbjct: 1362 SLNFRKIPPLVHSKTPEGNNGRSGDPRPQAAEPPDHLTITRRRTWSRDEVMGDNLLLSSV 1421
Query: 1406 SQLSQAIRENTEHLAEKMKILFQNTGRAWEDLEARINAENEVPILKTSNKEISSILKELR 1465
Q S+ IR++ + A K++ILF++ R W+D+E+++ AE+EVPI+KTS+ EISSIL+EL+
Sbjct: 1422 FQFSKKIRQSIDKTAGKIRILFKDKDRNWDDIESKLRAESEVPIVKTSSMEISSILQELK 1481
Query: 1466 RVQKQLEVINAIVDPSGSLDLLTGNRSLASSAQP 1499
RV+KQL+ INA++DP G+L+ L N S+ P
Sbjct: 1482 RVEKQLQAINAMIDPDGTLEAL-NNMGFPSAMLP 1514
>gi|109255230 centrosomal protein 170kDa isoform beta [Homo sapiens]
Length = 1486
Score = 347 bits (891), Expect = 4e-95
Identities = 198/402 (49%), Positives = 254/402 (63%), Gaps = 29/402 (7%)
Query: 1 MSATSWFLVSSSGARHRLPRELIFVGREECELMLQSRSVDKQHAVINYDQDRDEHWVKDL 60
MS TSWFLVSS G RHRLPRE+IFVGR++CELMLQSRSVDKQHAVINYD DEH VKDL
Sbjct: 1 MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDL 60
Query: 61 GSLNGTFVNDMRIPDQKYVTLKLNDVIRFGYDSNMYVLERVQHRVPEEALKHEKYTSQLQ 120
GSLNGTFVND+RIP+Q Y+TLKL D +RFGYD+N++ + + + RVPEEALKHEK+T QLQ
Sbjct: 61 GSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQ 120
Query: 121 VSVKGLAPKRSEALPEHTPYCEASNPRPE---------KGDRRPGTEAASYR-TPLYGQP 170
+S K + S++ + + ++ E K + + +A R TPLYGQP
Sbjct: 121 LSQKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQP 180
Query: 171 SWWGEDDGSTLPDAQRQGEPYPERPKGPVQQDG----ELHGFRAPAEPQGC-SFRREPSY 225
SWWG+D+ + G+P + + G ++ A A + F REPSY
Sbjct: 181 SWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCGIDAKQVEEQSAAANEEVLFPFCREPSY 240
Query: 226 FEIPTKETPQPSQPPEVPAHEMPTKDAEAGGGGAAPVVQSHASFTIEFDDCSPGKMKIKD 285
FEIPTKE QPSQ E HE+PTKD + A HASFTIEFDD +PGK+ I+D
Sbjct: 241 FEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGA----GHASFTIEFDDSTPGKVTIRD 296
Query: 286 HITKFSLRQRRPPGKEATPGE---------MVSAETKVADWLVQNDPSLLHRVGPGDDRH 336
H+TKF+ QR K+++PG M++ E KVADWL QN+P + +D
Sbjct: 297 HVTKFTSDQRH-KSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSK 355
Query: 337 STKSDLPVHTRTLKGHKHEDGTQSDSEDPLAKAASAAGVPLE 378
S KSD+PV+ + LKG+KH+DGTQSDSE+ A + LE
Sbjct: 356 SIKSDVPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLE 397
Score = 307 bits (786), Expect = 6e-83
Identities = 316/1057 (29%), Positives = 496/1057 (46%), Gaps = 189/1057 (17%)
Query: 580 EVEEARKMIDQ--VFGVLESPELSRASSATFRPVIRGD-RDESDDGGVAQRMALLQEFAS 636
+V+ K DQ VFGV ++ + +R PVI +D D ++ A+++E
Sbjct: 412 KVQATEKHQDQAVVFGVDDNQDYNR-------PVINEKHKDLIKDWALSSAAAVMEE--R 462
Query: 637 RPLGAAPQAEHQGLPVPGSPGGQKWVSRWASLADSYS-------------------DPGL 677
+PL + H S G ++WVS+WASLA +++ + +
Sbjct: 463 KPLTTS--GFHHSEEGTSSSGSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEI 520
Query: 678 TEDGLGRRGGEPEGSLPV---RMRRRLPQLPSERA--DSPAGPESSRRSGPGPPE----L 728
+E G+ R SL R RR LPQLP+E +S ++RS G +
Sbjct: 521 SESGMTVRSTGSATSLASQGERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQ 580
Query: 729 DSEQPSRLFGQEELDPDS-LSDASGSDGGR---------------GPEPGVEPQDSRRRS 772
+ E P++++ +++ D D LS + + G PG E ++ + +
Sbjct: 581 EKETPTQVYQKDKQDADRPLSKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKET 640
Query: 773 PQEGPTWSR-GRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPP 831
T ++ ++ R + TP + +G R+ E Q +QP P
Sbjct: 641 SLVKQTLAKLQQQEQREEAQWTPTKLSSKNVSGQTDKCRE--------ETFKQESQP--P 690
Query: 832 ARDGVYVSANGRMVIQLRPGR--------SPEPDG-----PAPAFLRQESFTKEPASGPP 878
++ + ++ G V Q R S P G + + +RQ SFT E P
Sbjct: 691 EKNSGHSTSKGDRVAQSESKRRKAEEILKSQTPKGGDKKESSKSLVRQGSFTIEK----P 746
Query: 879 APGKP----PHI----SSHPLLQDLAATRAARMDFHSQ--------DTHLILKETETALA 922
+P P PHI SS P LA T A+R+ S+ DT LILK+TE +A
Sbjct: 747 SPNIPIELIPHINKQTSSTP--SSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMA 804
Query: 923 ALEARLLS-NSVDAECEGGSTPRPPED-ALSGDSDVDTASTVSLRSGKSGPSPTTPQP-- 978
LEA+L N D EG TP D ++S +SDVDTAST+SL +G++ T +
Sbjct: 805 FLEAKLREDNKTD---EGPDTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSF 861
Query: 979 LRAQKEMSPSPPAAQDPGGTALVSAREQSSERQHHPLGPTDMGRGEPVRRSAIRRGHRPR 1038
K+ + ++D ++ ARE+ ++ TD+G R+ G +
Sbjct: 862 TSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSR--STDVGSRADGRKFVQSSGRIRQ 919
Query: 1039 GSLDWPSEERGPVLAHLPSSDVMASNHETPEATGAGRLGSRRKPAAPPPSPAAREEQSR- 1097
S+D +++ + H SD+M+S+ ET GR P + A S+
Sbjct: 920 PSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRT---------PLTSADEHVHSKL 970
Query: 1098 --SSASSQKGPQALTRSNSLST----PRPTRASRLRRARLGDASDTEAADGERGSLGNP- 1150
S + K ++ S+S ST PRPTR S LRRARLG+ASD+E AD ++ S+ +
Sbjct: 971 EGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELADADKASVASEV 1030
Query: 1151 --------EPVGRPAAEQAKKLSRLDILAMPRK-RAGSFTGTSDPEAAPARTSFSGRSVE 1201
P GR + +SR+D+LA PR+ R GS + SD EA +R+S S R+ E
Sbjct: 1031 STTSSTSKPPTGR------RNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASSRTAE 1084
Query: 1202 --------LCCASRKPTMAEARAVSR----KAANTATTTGPRQPFSRARSGSARYTSTTQ 1249
L + + A ++SR K + + G SR R Y ST++
Sbjct: 1085 AIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASVNSRWRRFPTDYASTSE 1144
Query: 1250 ----------------TPRAGSSSRARSRAPG-PRDTDDDEEEPDPYGFIVQ-TAEIAEI 1291
T A ++R +S P + + +I TA EI
Sbjct: 1145 DEFGSNRNSPKHTRLRTSPALKTTRLQSAGSAMPTSSSFKHRIKEQEDYIRDWTAHREEI 1204
Query: 1292 ARLSQTLVKDVAILAQEIHDVAGDGDTLGSSEPAHSASLSNMPSTPASTISAREELVQRI 1351
AR+SQ D+A++A+EI+DVAG+ D++ SS A S ++S +TP S I REELV R+
Sbjct: 1205 ARISQ----DLALIAREINDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDTREELVDRV 1260
Query: 1352 PEASLNFQKVPP---------GSLNSRDFDQNMNDSCEDALANKTRPRNREEVIFDNLML 1402
+ SLNF+K+PP + S D + + + R +R+EV+ DNL+L
Sbjct: 1261 FDESLNFRKIPPLVHSKTPEGNNGRSGDPRPQAAEPPDHLTITRRRTWSRDEVMGDNLLL 1320
Query: 1403 NPVSQLSQAIRENTEHLAEKMKILFQNTGRAWEDLEARINAENEVPILKTSNKEISSILK 1462
+ V Q S+ IR++ + A K++ILF++ R W+D+E+++ AE+EVPI+KTS+ EISSIL+
Sbjct: 1321 SSVFQFSKKIRQSIDKTAGKIRILFKDKDRNWDDIESKLRAESEVPIVKTSSMEISSILQ 1380
Query: 1463 ELRRVQKQLEVINAIVDPSGSLDLLTGNRSLASSAQP 1499
EL+RV+KQL+ INA++DP G+L+ L N S+ P
Sbjct: 1381 ELKRVEKQLQAINAMIDPDGTLEAL-NNMGFPSAMLP 1416
>gi|109255232 centrosomal protein 170kDa isoform gamma [Homo
sapiens]
Length = 1460
Score = 347 bits (891), Expect = 4e-95
Identities = 198/402 (49%), Positives = 254/402 (63%), Gaps = 29/402 (7%)
Query: 1 MSATSWFLVSSSGARHRLPRELIFVGREECELMLQSRSVDKQHAVINYDQDRDEHWVKDL 60
MS TSWFLVSS G RHRLPRE+IFVGR++CELMLQSRSVDKQHAVINYD DEH VKDL
Sbjct: 1 MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDL 60
Query: 61 GSLNGTFVNDMRIPDQKYVTLKLNDVIRFGYDSNMYVLERVQHRVPEEALKHEKYTSQLQ 120
GSLNGTFVND+RIP+Q Y+TLKL D +RFGYD+N++ + + + RVPEEALKHEK+T QLQ
Sbjct: 61 GSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQ 120
Query: 121 VSVKGLAPKRSEALPEHTPYCEASNPRPE---------KGDRRPGTEAASYR-TPLYGQP 170
+S K + S++ + + ++ E K + + +A R TPLYGQP
Sbjct: 121 LSQKSSESELSKSASAKSIDSKVADAATEVQHKTTEALKSEEKAMDISAMPRGTPLYGQP 180
Query: 171 SWWGEDDGSTLPDAQRQGEPYPERPKGPVQQDG----ELHGFRAPAEPQGC-SFRREPSY 225
SWWG+D+ + G+P + + G ++ A A + F REPSY
Sbjct: 181 SWWGDDEVDEKRAFKTNGKPEEKNHEAGTSGCGIDAKQVEEQSAAANEEVLFPFCREPSY 240
Query: 226 FEIPTKETPQPSQPPEVPAHEMPTKDAEAGGGGAAPVVQSHASFTIEFDDCSPGKMKIKD 285
FEIPTKE QPSQ E HE+PTKD + A HASFTIEFDD +PGK+ I+D
Sbjct: 241 FEIPTKEFQQPSQITESTIHEIPTKDTPSSHITGA----GHASFTIEFDDSTPGKVTIRD 296
Query: 286 HITKFSLRQRRPPGKEATPGE---------MVSAETKVADWLVQNDPSLLHRVGPGDDRH 336
H+TKF+ QR K+++PG M++ E KVADWL QN+P + +D
Sbjct: 297 HVTKFTSDQRH-KSKKSSPGTQDLLGIQTGMMAPENKVADWLAQNNPPQMLWERTEEDSK 355
Query: 337 STKSDLPVHTRTLKGHKHEDGTQSDSEDPLAKAASAAGVPLE 378
S KSD+PV+ + LKG+KH+DGTQSDSE+ A + LE
Sbjct: 356 SIKSDVPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLE 397
Score = 308 bits (788), Expect = 3e-83
Identities = 316/1042 (30%), Positives = 490/1042 (47%), Gaps = 185/1042 (17%)
Query: 580 EVEEARKMIDQ--VFGVLESPELSRASSATFRPVIRGD-RDESDDGGVAQRMALLQEFAS 636
+V+ K DQ VFGV ++ + +R PVI +D D ++ A+++E
Sbjct: 412 KVQATEKHQDQAVVFGVDDNQDYNR-------PVINEKHKDLIKDWALSSAAAVMEE--R 462
Query: 637 RPLGAAPQAEHQGLPVPGSPGGQKWVSRWASLADSYS-------------------DPGL 677
+PL + H S G ++WVS+WASLA +++ + +
Sbjct: 463 KPLTTS--GFHHSEEGTSSSGSKRWVSQWASLAANHTRHDQEERIMEFSAPLPLENETEI 520
Query: 678 TEDGLGRRGGEPEGSLPV---RMRRRLPQLPSERA--DSPAGPESSRRSGPGPPE----L 728
+E G+ R SL R RR LPQLP+E +S ++RS G +
Sbjct: 521 SESGMTVRSTGSATSLASQGERRRRTLPQLPNEEKSLESHRAKVVTQRSEIGEKQDTELQ 580
Query: 729 DSEQPSRLFGQEELDPDS-LSDASGSDGGR---------------GPEPGVEPQDSRRRS 772
+ E P++++ +++ D D LS + + G PG E ++ + +
Sbjct: 581 EKETPTQVYQKDKQDADRPLSKMNRAVNGETLKTGGDNKTLLHLGSSAPGKEKSETDKET 640
Query: 773 PQEGPTWSR-GRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPP 831
T ++ ++ R + TP + +G R+ E Q +QP P
Sbjct: 641 SLVKQTLAKLQQQEQREEAQWTPTKLSSKNVSGQTDKCRE--------ETFKQESQP--P 690
Query: 832 ARDGVYVSANGRMVIQLRPGR--------SPEPDG-----PAPAFLRQESFTKEPASGPP 878
++ + ++ G V Q R S P G + + +RQ SFT E P
Sbjct: 691 EKNSGHSTSKGDRVAQSESKRRKAEEILKSQTPKGGDKKESSKSLVRQGSFTIEK----P 746
Query: 879 APGKP----PHI----SSHPLLQDLAATRAARMDFHSQ--------DTHLILKETETALA 922
+P P PHI SS P LA T A+R+ S+ DT LILK+TE +A
Sbjct: 747 SPNIPIELIPHINKQTSSTP--SSLALTSASRIRERSESLDPDSSMDTTLILKDTEAVMA 804
Query: 923 ALEARLLS-NSVDAECEGGSTPRPPED-ALSGDSDVDTASTVSLRSGKSGPSPTTPQP-- 978
LEA+L N D EG TP D ++S +SDVDTAST+SL +G++ T +
Sbjct: 805 FLEAKLREDNKTD---EGPDTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSF 861
Query: 979 LRAQKEMSPSPPAAQDPGGTALVSAREQSSERQHHPLGPTDMGRGEPVRRSAIRRGHRPR 1038
K+ + ++D ++ ARE+ ++ TD+G R+ G +
Sbjct: 862 TSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSR--STDVGSRADGRKFVQSSGRIRQ 919
Query: 1039 GSLDWPSEERGPVLAHLPSSDVMASNHETPEATGAGRLGSRRKPAAPPPSPAAREEQSR- 1097
S+D +++ + H SD+M+S+ ET GR P + A S+
Sbjct: 920 PSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKPHGRT---------PLTSADEHVHSKL 970
Query: 1098 --SSASSQKGPQALTRSNSLST----PRPTRASRLRRARLGDASDTEAADGERGSLGNP- 1150
S + K ++ S+S ST PRPTR S LRRARLG+ASD+E AD ++ S+ +
Sbjct: 971 EGSKVTKSKTSPVVSGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELADADKASVASEV 1030
Query: 1151 --------EPVGRPAAEQAKKLSRLDILAMPRK-RAGSFTGTSDPEAAPARTSFSGRSVE 1201
P GR + +SR+D+LA PR+ R GS + SD EA +R+S S R+ E
Sbjct: 1031 STTSSTSKPPTGR------RNISRIDLLAQPRRTRLGSLSARSDSEATISRSSASSRTAE 1084
Query: 1202 LCCASRKPTMAEARAVSRKAANTATTTGPRQPFSRARS-GSARYTSTTQTPRAGS----S 1256
S + + R AN+ + + S + GSA TT+ AGS S
Sbjct: 1085 AIIRSGARLVPSDKFSPRIRANSISRLSDSKVKSMTSAHGSASALKTTRLQSAGSAMPTS 1144
Query: 1257 SRARSRAPGPRDTDDDEEEPDPYGFIVQTAEIAEIARLSQTLVKDVAILAQEIHDVAGDG 1316
S + R D D TA EIAR+SQ D+A++A+EI+DVAG+
Sbjct: 1145 SSFKHRIKEQEDYIRD-----------WTAHREEIARISQ----DLALIAREINDVAGEI 1189
Query: 1317 DTLGSSEPAHSASLSNMPSTPASTISAREE----------LVQRIPEASLNFQKVPP--- 1363
D++ SS A S ++S +TP S I REE LV R+ + SLNF+K+PP
Sbjct: 1190 DSVTSSGTAPSTTVSTAATTPGSAIDTREEVGDLHGEMHKLVDRVFDESLNFRKIPPLVH 1249
Query: 1364 ------GSLNSRDFDQNMNDSCEDALANKTRPRNREEVIFDNLMLNPVSQLSQAIRENTE 1417
+ S D + + + R +R+EV+ DNL+L+ V Q S+ IR++ +
Sbjct: 1250 SKTPEGNNGRSGDPRPQAAEPPDHLTITRRRTWSRDEVMGDNLLLSSVFQFSKKIRQSID 1309
Query: 1418 HLAEKMKILFQNTGRAWEDLEARINAENEVPILKTSNKEISSILKELRRVQKQLEVINAI 1477
A K++ILF++ R W+D+E+++ AE+EVPI+KTS+ EISSIL+EL+RV+KQL+ INA+
Sbjct: 1310 KTAGKIRILFKDKDRNWDDIESKLRAESEVPIVKTSSMEISSILQELKRVEKQLQAINAM 1369
Query: 1478 VDPSGSLDLLTGNRSLASSAQP 1499
+DP G+L+ L N S+ P
Sbjct: 1370 IDPDGTLEAL-NNMGFPSAMLP 1390
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 76.3 bits (186), Expect = 2e-13
Identities = 274/1221 (22%), Positives = 421/1221 (34%), Gaps = 191/1221 (15%)
Query: 143 ASNPRPEKGDRRPGTEAASYRTPLYGQPSWWGEDDGS-TLPDAQRQGEPYPERPKGPVQQ 201
+S+P P++ + P ++ S +P S GS T P A Q R
Sbjct: 818 SSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSP 877
Query: 202 DGELHGFRAPAEPQGCSFRREPSY-FEIPTKETPQPSQPPE--VPAHEMPTKDAEAGGGG 258
D EL R P+ CS P P +++P S P+ V A P + + +G
Sbjct: 878 DPELKS-RTPSR-HSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSS 935
Query: 259 AAPVVQSHASFTIEFDDCSPGKMKIKDHITKFSLRQRRPPGKEATPGEMVSAETKVADWL 318
+P + + SP + ++S P + P + +
Sbjct: 936 PSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPE---TPPRQSHSGS 992
Query: 319 VQNDPSLLHRVGPGDDRHSTKSDLPVHTRTLKGHKHEDGTQSDSEDPLAKAAS--AAGVP 376
+ P + + PG +KS P K +D L+ A ++ P
Sbjct: 993 ISPYPKVKAQTPPGPSLSGSKSPCPQE-------KSKDSLVQSCPGSLSLCAGVKSSTPP 1045
Query: 377 LEA--SGEQVRLQRQIKRDPQELLHNQQAFVIEFFDEDTPRKKRSQSFTHSPSGDPKADK 434
E+ ++L+ Q + P V + E + +SQ+ PK +
Sbjct: 1046 GESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQT-------SPKGGR 1098
Query: 435 RRGPTPADRDRPSVPAPVQAGGRSSGPQRAGSLKREKTEERLGSPSPASRTPARPFGSVG 494
R +P P G S+ P LK + E+ S +S P S+
Sbjct: 1099 SRSSSPVTELASRSPIRQDRGEFSASPM----LKSGMSPEQSRFQSDSSSYPTVDSNSLL 1154
Query: 495 RRSRL----AQDFMAQCLRESSPAARPSPEKVPPVLPAPLTPHGTSPVGPPT--PPPAPT 548
+SRL +++ MA +E + A+ P + P P +S V T PP
Sbjct: 1155 GQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPE-SSLVFKDTLRTPPRER 1213
Query: 549 DPQLTKARKQEEDDSLSDAGTYTIETEAQDTE----VEEARKMIDQVFGVLESPELSRAS 604
+ +E++ +L T +QD E VE++ + Q+ L S EL S
Sbjct: 1214 SGAGSSPETKEQNSALP--------TSSQDEELMEVVEKSEEPAGQILSHLSS-ELKEMS 1264
Query: 605 SATF--------RPVIRGDRDESDDGGVAQRMALLQEFASRPLGAAPQAEHQGLPVPG-- 654
++ F RP + D+S QA + + VP
Sbjct: 1265 TSNFESSPEVEERPAVSLTLDQSQS----------------------QASLEAVEVPSMA 1302
Query: 655 -SPGGQKWVSRWASLADSYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERADSPA 713
S GG + L++S L E+ G P+ R P L +E +
Sbjct: 1303 SSWGGPHFSPEHKELSNS----PLRENSFGS---------PLEFRNSGP-LGTEMNTGFS 1348
Query: 714 GPESSRRSGP------GPPELD-SEQPSRLFGQE--ELDPDSLSDASGSDGGRGPEP--- 761
+GP P LD EQ +R G EL PD++ A S P
Sbjct: 1349 SEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLD 1408
Query: 762 GVEPQDSRRRSPQ-EGPTWSRGRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGE 820
V SR RS P G PR P + + G ++G SR L+ G
Sbjct: 1409 AVPRTPSRERSSSASSPEMKDGL--PRTPSRRSRSGSSPGLRDGSGTPSRHSLS--GSSP 1464
Query: 821 GLGQTAQPSPPARDGVYVSANGRMVIQLRPGRSPEPDGPAPAFLRQESFTKE-PASGPPA 879
G+ + R S + + Q RS P P L + T + SG +
Sbjct: 1465 GMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPE---LNNKCLTPQRERSGSES 1521
Query: 880 PGKPPHISSHPLLQDLAATRAARMDFHSQDTHLILKETETALAALEARLLSNSVDAECEG 939
++ PL Q + + +D A+ + R S+S
Sbjct: 1522 SVDQKTVARTPLGQRSRSGSSQELDVKPS-------------ASPQERSESDSSPDSKAK 1568
Query: 940 GSTPRPPEDALSGDSDVDTASTVSLRSGKSGPSPTTPQPLRAQKEM---SPSPPAAQDPG 996
TP +VD+ S +S R +SG SP RA S S P + P
Sbjct: 1569 TRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPA 1628
Query: 997 GTALVS-AREQSSERQHHPL----GPTDMGRGEPVRRSAIRRGHR----PRGSLDWPSEE 1047
AL +R SS + P T+ P + RRG R P+ P
Sbjct: 1629 PRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRR 1688
Query: 1048 RG----PVL---AHLPSSDVMASNHETPEATGAGRLGSRRKPAAPPPSPAAREEQSR--- 1097
R P L A L AS+ +PE RR P+ P PA + SR
Sbjct: 1689 RSSRSSPELTRKARLSRRSRSASS--SPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRR 1746
Query: 1098 ------SSASSQKG------PQALTRSNSLSTPRPTRASRLR----------RARLGDAS 1135
+ +S++G P+ L RS S S TR +R R R R S
Sbjct: 1747 SASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRS 1806
Query: 1136 DTEAADGERGSLG--NPEPVGRPAAEQAKKLSRLDILAMP--RKRAGSFTGT-----SDP 1186
+ RG G + P + ++ + + R P RKR+ S T S
Sbjct: 1807 RSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRS 1866
Query: 1187 EAAPARTSFSGRSVELCCASRKPTMAEARAVSRKAANTATTTGPRQPFSRARSGSARYTS 1246
A+PA S L SR+ + + VSR+ + + T+ R+ SRA S +R S
Sbjct: 1867 RASPATHRRSRSRTPLI--SRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRA-SPVSRRRS 1923
Query: 1247 TTQTPRAGSSSRARSRAPGPR 1267
++TP + R+RSR P R
Sbjct: 1924 RSRTPPV-TRRRSRSRTPTTR 1943
Score = 69.7 bits (169), Expect = 2e-11
Identities = 146/659 (22%), Positives = 223/659 (33%), Gaps = 95/659 (14%)
Query: 711 SPAGPESSRRSGPGPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSRR 770
S G S++R P PE ++QPS + ++ D S S G EP
Sbjct: 311 SEPGTTSTQR--PSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEP----- 363
Query: 771 RSPQEGPTWSRGRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSP 830
P P + R G P P + LS++P+ P + + P
Sbjct: 364 --PAPTPLLAE-----RHGGSPQPLA--------TTPLSQEPVNPPSEASPTRDRSPPKS 408
Query: 831 PARDGVYVSANGRMVIQLRPGRSPEPDGPAPA---FLRQESFTKEPASGPPAPGKPPHIS 887
P + L S E P+P R S + E PAPG IS
Sbjct: 409 PEK--------------LPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREIS 454
Query: 888 SHPLLQDLAATRAARMDFHSQDTHLILKETETALAALEARLLSNSVDAECEGGSTPRPPE 947
S P ++ + RA R HS + + + A R S S G S R P+
Sbjct: 455 SSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGR--SRSRTPTKRGHSRSRSPQ 512
Query: 948 DALSGDSDVDTASTVSLRSGKSGPSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAREQS 1007
S + R G+S P R + SP P T +
Sbjct: 513 WRRSRSAQ---------RWGRS------RSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSA 557
Query: 1008 SERQHHPLGPTDMGRGEPVRRSAIRRGH-RPRGSLDWPSEERGPVLAHLPSSDVMASNHE 1066
+ H P GR R+ RRG R R S R P S
Sbjct: 558 RRGRSHSRSPATRGRSR--SRTPARRGRSRSRTPARRRSRSRTPTRRR--------SRSR 607
Query: 1067 TPEATGAGRLGSRRKPAAPPPSPAAREEQSRSSA-----SSQKGPQALTRSNSLSTPRPT 1121
TP G R + + + SP R +SRS A S + P RS S + R
Sbjct: 608 TPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRG 667
Query: 1122 RASRLRRARLGDASDTEAADGERGSLGNPEPVGRPAAEQAKKLSRLDILAMPRK-RAGSF 1180
R+ AR S + S GR + + R R+ R+GS
Sbjct: 668 RSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSS 727
Query: 1181 TGTSDPEAAPARTSFSGRSVEL------CCASRKPTMAEARAVSR---KAANTATTTGPR 1231
+ + R S S S E+ SR + ++A SR + + + ++ P+
Sbjct: 728 SERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPK 787
Query: 1232 Q----PFSRARSGSARYTSTTQTP----RAGSSSRARSRAPGPRDTDDDEEEPDPYGFIV 1283
Q P R+RSGS++ + ++TP R+ SS + ++ P P P V
Sbjct: 788 QKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPK---V 844
Query: 1284 QTAEIAEIARLSQTLVKDVAILAQ--EIHDVAGDGDTLGSSEPAHSASLSNMPSTPAST 1340
++ ++ + ++ Q + + D + + HS S S+ P +ST
Sbjct: 845 KSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSST 903
Score = 59.3 bits (142), Expect = 3e-08
Identities = 201/892 (22%), Positives = 295/892 (33%), Gaps = 167/892 (18%)
Query: 422 FTHSPSGDPKADKRRGPTPADRDRPSVPAP--VQAGGRSSGPQRAG----SLKREKTEER 475
F + DP D + T + S +P V+ G SS + ++ R + ER
Sbjct: 1359 FLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRER 1418
Query: 476 LGSPSPASRTPARPFGSVGRRSRLAQDFMAQCLRESS--PAARPSPEKVPPVLPAPLTP- 532
S S +P G SR ++ + LR+ S P+ P + P TP
Sbjct: 1419 SSSAS----SPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPS 1474
Query: 533 HGTSPV-GPPTPPPAPTDPQLTKARKQEEDDSLSDAGTYTIETEAQDTEVEE---ARKMI 588
G S P P P P+ ++R + + T E ++ V++ AR +
Sbjct: 1475 RGRSECDSSPEPKALPQTPR-PRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPL 1533
Query: 589 DQVFGVLESPELSRASSATFRPVIRGDRDESDDGGVAQRMALLQEFASRPLGAAPQAEHQ 648
Q S EL SA+ P R + D S D R L Q S G++P+ + +
Sbjct: 1534 GQRSRSGSSQELDVKPSAS--PQERSESDSSPDSKAKTRTPLRQRSRS---GSSPEVDSK 1588
Query: 649 GLPVPGSPGGQKWVSRWASLADSYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSER 708
P R G PE ++ + P +
Sbjct: 1589 SRLSPRR---------------------------SRSGSSPE------VKDKPRAAPRAQ 1615
Query: 709 ADSPAGPESSRRSGPGPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDS 768
+ S + PE P P L P R S S +S G P E S
Sbjct: 1616 SGSDSSPEPK---APAPRAL----PRR----------SRSGSSSKGRG----PSPEGSSS 1654
Query: 769 RRRSPQEGPTWSRGRRSPRAPGEP-----TP----ASFFIGDQNGDAVLSRKPLAAPGDG 819
SP+ P RR R+ EP TP +S + A LSR+ +A
Sbjct: 1655 TESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSP 1714
Query: 820 EGLGQTAQPSPPARDGVYVSANGRMVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGP-- 877
E T +PP R RSP P PA + S + AS P
Sbjct: 1715 E----TRSRTPP-----------------RHRRSPSVSSPEPAEKSRSSRRRRSASSPRT 1753
Query: 878 ---------PAPGKPPHISSHPLLQDLAATRAARMDFHSQDTHLILKETETALAALEARL 928
P+P KP + TR R S + + + + +
Sbjct: 1754 KTTSRRGRSPSP-KPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRS------ 1806
Query: 929 LSNSVDAECEGGS-----TPRPPEDALSGDSDVDTASTVSLRSGKSGPSPTTPQPLRAQK 983
+ V GGS +P E + + S S K S T+P P + +
Sbjct: 1807 -RSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSR 1865
Query: 984 EMSPSPPAAQDPGGTALVSAREQSSERQHHPLGPTDMGRGEPVRRSAIRRGHRPRGSLDW 1043
+ + T L+S R S P R R S RR R R S
Sbjct: 1866 SRASPATHRRSRSRTPLISRRRSRSR-----TSPVSRRRSRS-RTSVTRRRSRSRAS--- 1916
Query: 1044 PSEERGPVLAHLPSSDVMASNHETPEATGAGRLGSRRKPAAPPPSPAAREEQSRSSASSQ 1103
R + P S TP T R SR P S + +R + S+
Sbjct: 1917 -PVSRRRSRSRTPPVTRRRSRSRTP--TTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSR 1973
Query: 1104 KGPQALTRSNSLSTPRPTRASRLRRARLGDASDTEAADGERGSLGNPEPVGR-------P 1156
P RS S ++P R SR R + + R S PV R P
Sbjct: 1974 TSPITRRRSRSRTSPVTRRRSRSRTSPV----------TRRRSRSRTSPVTRRRSRSRTP 2023
Query: 1157 AAEQAKKLSRLDILAMPRKRAGSFTGTSDPEAAPARTSFSGRSVELCCASRKPTMAEARA 1216
A + + SR +L PRKR+ S + + + +RT + R +R P R+
Sbjct: 2024 PAIRRRSRSRTPLL--PRKRSRSRSPLAIRRRSRSRTPRTARGKR--SLTRSPPAIRRRS 2079
Query: 1217 VSRKAANTATTTGPRQPFSRARSGSARYTSTTQTPRAGSSSRARSRAPGPRD 1268
S +++ + + P P +R SGS + R SR S +P P D
Sbjct: 2080 ASGSSSDRSRSATP--PATRNHSGSRTPPVALNSSRMSCFSRP-SMSPTPLD 2128
Score = 58.2 bits (139), Expect = 6e-08
Identities = 187/884 (21%), Positives = 284/884 (32%), Gaps = 97/884 (10%)
Query: 415 RKKRSQSFTHSPSGDPKADKRRGPTPADRDRPSVPAPVQAGGRSSGPQRAGSLKREKTEE 474
RKK S+ H + K K R PTP + + + RS+ P T
Sbjct: 209 RKKSSKKKKHRSESESKKRKHRSPTPKSKRKSK--DKKRKRSRSTTPAPKSRRAHRSTSA 266
Query: 475 RLGSPSPASRTPARPFGSVGRRSRLAQDFMAQCLRESSPAARPSPEKVPPVLPAPLTPHG 534
S S SR+ +R + + LA R SPA+ E P P T
Sbjct: 267 DSASSSDTSRSRSRSAAAKTHTTALAG-------RSPSPASGRRGEGDAP-FSEPGTTST 318
Query: 535 TSPVGPPTPPPAPTDPQLTKARKQEEDDSLSDAGTYTIETEAQDTEVEEARKMIDQVFGV 594
P P T P+ P K + ++E + + + E + E ++ + G
Sbjct: 319 QRPSSPETATKQPSSPYEDKDKDKKEKSATRPSP--SPERSSTGPEPPAPTPLLAERHG- 375
Query: 595 LESPELSRASSATFRPV-----IRGDRDESDDGGVAQRMALLQEFASRPLGAAPQAEHQG 649
SP+ + + PV RD S + L Q +S +PQ
Sbjct: 376 -GSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEK---LPQSSSSESSPPSPQPTKVS 431
Query: 650 LPVPGSPGGQKWVSRWASLADSYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERA 709
SP K S + S P GR + S PS R
Sbjct: 432 RHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHS----------HTPSRRM 481
Query: 710 DSPAGPESSRRSGPGPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSR 769
P +++R S P++ P S GR P + R
Sbjct: 482 GRSRSPATAKRG-----RSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSP---QRRGR 533
Query: 770 RRSPQEGPTWSRGRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPS 829
RSPQ P WSR R + R G A A R P G++ +
Sbjct: 534 SRSPQR-PGWSRSRNTQRR-GRSRSARRGRSHSRSPATRGRSRSRTPA---RRGRSRSRT 588
Query: 830 PPARDGVYVSANGRMVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSH 889
P R + R P R PA R+ S T+ P P S
Sbjct: 589 PARRRSRSRTPTRRRSRSRTPARRGRSRSRTPA--RRRSRTRSPVRRRSRSRSPARRSG- 645
Query: 890 PLLQDLAATRAARMDFHSQDTHLILKETETALAALEARLLSNSVDAECEGGSTPRPPEDA 949
+ + T A R S+ + A R S S G S R P
Sbjct: 646 ---RSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGR--SRSRTPARRGRSRSRTPRRG 700
Query: 950 LSGDSDV----DTASTVSLRSGKSGPSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSARE 1005
S + + S R G+SG S R + S S + + +
Sbjct: 701 RSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPE-------MKKSR 753
Query: 1006 QSSERQHHPLGPTDMGRGEPVRRSAIRRGHRPRGSLDWPSEERGPVLAHLPSSDVMASNH 1065
SS R P R + R ++RR + P + SS A +
Sbjct: 754 ISSRRSRSLSSP----RSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSR 809
Query: 1066 ETPEATGAGRLGSRRKPAAPPPSPAAREEQSRSSASSQKGPQALT----RSNSLSTPRPT 1121
P + R ++PPP ++ +S +SS P+ + R S+++P+
Sbjct: 810 TPPRRS--------RSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQAN 861
Query: 1122 RAS--RLRRARLGDASDTE--AADGERGSLGNPEP----VGRPAAEQAKKLS----RLDI 1169
S RR+ + D E + R S P P + + S ++
Sbjct: 862 EQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKA 921
Query: 1170 LAMPRKRAGSFTGTSDPEAAPARTS-FSGRSVELCCASRKPTMAEARAVSRKAANTATTT 1228
+ PR+R+ S + + P +RT+ RSV C S + R +++ T
Sbjct: 922 IISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPC--SNVESRLLPRYSHSGSSSPDTKV 979
Query: 1229 GPRQPFSRARSGS-ARYTST-TQTPRAGSSSRARSRAPGPRDTD 1270
P P ++ SGS + Y QTP S S ++S P + D
Sbjct: 980 KPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKD 1023
Score = 55.8 bits (133), Expect = 3e-07
Identities = 185/813 (22%), Positives = 269/813 (33%), Gaps = 119/813 (14%)
Query: 672 YSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERADSPAGPESSRRSGPGP------ 725
+S+PG T +R PE + + P P E D +S+ R P P
Sbjct: 310 FSEPGTTST---QRPSSPETAT------KQPSSPYEDKDKDKKEKSATRPSPSPERSSTG 360
Query: 726 PELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSRR--RSPQEGPTWSRGR 783
PE + P L + P L+ S P P R +SP++ P S
Sbjct: 361 PEPPAPTPL-LAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSE 419
Query: 784 RSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSANGR 843
SP +P +PT S + S KP APG + + + +
Sbjct: 420 SSPPSP-QPTKVS----RHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHS 474
Query: 844 MVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSHPLLQDLAATRAARM 903
R GRS P R + TK S +P S+ + + R R
Sbjct: 475 HTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRS 534
Query: 904 DFHSQDTHLILKETETALAALEARL-LSNSVDAECEGGSTPRPPEDALSGDSDVDTASTV 962
+ + T+ + AR S+S G S R P A G S T +
Sbjct: 535 RSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTP--ARRGRSRSRTPARR 592
Query: 963 SLRS-------------GKSGPSPTTPQPLRAQKEMSP-------SPPAAQDPGGTALVS 1002
RS + G S + R + SP PA + +
Sbjct: 593 RSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTP 652
Query: 1003 AREQSSERQHHPLGPTDMGRGE---PVRRSAIRRGHRP--RGSLDWPSEERGPVLAHLPS 1057
AR S + P GR P RRS R P RG S R P S
Sbjct: 653 ARRGRSRSRT----PARRGRSRSRTPARRSGRSRSRTPARRGR----SRSRTPRRGRSRS 704
Query: 1058 SDVMA---SNHETPEATGAGRLGSRRKPAAPPPSPAAREEQSRSSASSQKGPQALTRSNS 1114
++ S+ TP+ G S RK + + R +S SS +K + RS S
Sbjct: 705 RSLVRRGRSHSRTPQRRGRSGSSSERKNKS---RTSQRRSRSNSSPEMKKSRISSRRSRS 761
Query: 1115 LSTPRPTRASRLRRARLGDASDTEAADGERGSLGNPEPVGRPAAEQAKKLSRLDILAMPR 1174
LS+PR SRL R S + ++ + P R + Q K SR R
Sbjct: 762 LSSPRSKAKSRLSLRR----SLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSR---TPPRR 814
Query: 1175 KRAGSFTGTSDPEAAPARTSFSGRSVELCCASRKPTMAEARAVSRKAANTATTTGPRQ-- 1232
R+ S P+R S S S S P +++ AN + T R+
Sbjct: 815 SRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTP--PRQGSITSPQANEQSVTPQRRSC 872
Query: 1233 ------PFSRARSGSARYTSTTQTPRAGSS-----SRARSRAPGPR---------DTDDD 1272
P ++R+ S S + PR SS S +RS +P P+ +
Sbjct: 873 FESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSG 932
Query: 1273 EEEPDPYGFIVQTAEIAEIARLSQTLVKDVAILAQEIHDVAGDGDTLGSSE----PAHSA 1328
P P +T +S + +L + H + DT E +HS
Sbjct: 933 SSSPSPSRVTSRTTP-RRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSG 991
Query: 1329 SLSNMPSTPASTISAREELVQRIPEASLNFQKVPPGSLNSRDFDQNMNDSCEDALA---- 1384
S+S P A T P SL+ K P S+D ++ SC +L+
Sbjct: 992 SISPYPKVKAQT----------PPGPSLSGSKSPCPQEKSKD---SLVQSCPGSLSLCAG 1038
Query: 1385 -NKTRPRNREEVIFDNLMLNPVSQLSQAIRENT 1416
+ P +L L SQ S R +T
Sbjct: 1039 VKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDT 1071
Score = 55.1 bits (131), Expect = 5e-07
Identities = 99/411 (24%), Positives = 138/411 (33%), Gaps = 76/411 (18%)
Query: 441 ADRDRPSVPAPVQAGGRSSGPQRAGSLKREKTEERLGSPSPASRTPARPFGS--VGRRS- 497
AD P+ PA AG R+ A SL T + +SRTP P + VG RS
Sbjct: 2285 ADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSA 2344
Query: 498 ------RLAQDFMAQCLRESS-PAARPSPEKVPPVLPAPLTP-----HGTSPVGPP---- 541
+A A L +S +AR +P L +P P + PP
Sbjct: 2345 HATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDR 2404
Query: 542 ----TPPPAPTDPQLTKARKQEEDDSLSDAGTYTIETEAQDTEVEEARKMIDQVFGVLES 597
TPP AP+ ++T R + A + ++ AQD + R + F
Sbjct: 2405 ARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQD----QPRSPVPSAFS---- 2456
Query: 598 PELSRASSATFRPVIRGDRDESDDGGVAQRMALLQEFASRPLGAAPQAEHQGLPVPGSPG 657
+ SR A PV G VA + + AP H + P +
Sbjct: 2457 -DQSRCLIAQTTPV--AGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPAST 2513
Query: 658 GQKWVSRWASL------------------ADSYSDPGLTEDGLGRRGGEPEG-SLPVRMR 698
G + S A+L + S S + G + EG SLPV+
Sbjct: 2514 GAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPE 2573
Query: 699 RRLPQLPSERADSPAGPESSRRSGPGPP------------------ELDSEQPSRLFGQE 740
L ++PS +PA E+ R P P S S
Sbjct: 2574 VALKRVPS---PTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSS 2630
Query: 741 ELDPDSLSDASGSDGGRGPEPGVE-PQD-SRRRSPQEGPTWSRGRRSPRAP 789
S S +S S P P PQ + SP++ P R RSPR P
Sbjct: 2631 SSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKP 2681
Score = 53.5 bits (127), Expect = 2e-06
Identities = 203/917 (22%), Positives = 303/917 (33%), Gaps = 173/917 (18%)
Query: 416 KKRSQSFTHSPSGDPKADKRRGPTPADRDRPSVPAPVQAGGRSSGPQRAGSLKREKTEER 475
+KRS+S T SP+ ++ R P R R P + RS R + R ++ R
Sbjct: 1849 RKRSRSRT-SPAPWKRSRSRASPATHRRSRSRTPLISRRRSRS----RTSPVSRRRSRSR 1903
Query: 476 LGSPSPASRTPARPFGSVGRRSRLAQDFMAQCLRESSPAARPSPEKVPPVL-------PA 528
SR+ A P RSR + + R S + PPV
Sbjct: 1904 TSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTP 1963
Query: 529 PLTPHG----TSPV---------GPPTP--PPAPTDPQLTKARKQEEDDSLSDAGTYTIE 573
P+T TSP+ P T + T P +T+ R + ++ + +
Sbjct: 1964 PVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSP-VTRRRSRSRTSPVTRRRSRSRT 2022
Query: 574 TEAQDTEVEEARKMIDQVFGVLESPELSRASSATFRP-VIRGDRDESDDGGVAQRMALLQ 632
A ++ + SP R S + P RG R + +R +
Sbjct: 2023 PPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASG 2082
Query: 633 EFASRPLGAAPQA--EHQGLPVPGSPGGQKWVSRWASLADSYSDPGLTEDGLGRRGG--- 687
+ R A P A H G P V+ +S +S P ++ L R
Sbjct: 2083 SSSDRSRSATPPATRNHSGSRTPP-------VALNSSRMSCFSRPSMSPTPLDRCRSPGM 2135
Query: 688 -EPEGSLPVRMRRRLPQLPSERADSPAGPESSRRSGPGPPELDSEQPSRL----FGQEEL 742
EP GS M L Q D P GP PE ++ L
Sbjct: 2136 LEPLGSSRTPMSV-LQQAGGSMMDGP-GPRIPDHQRTSVPENHAQSRIALALTAISLGTA 2193
Query: 743 DPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQEG-----PTWSRGRR---SPRAPGEPTP 794
P A+G P P S R +P P S S R P PT
Sbjct: 2194 RPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTA 2253
Query: 795 ASFFIGDQNGDAVLSRKPLAAPG-----DGEGLGQTAQPSPPARDGVYVSANGRMVIQLR 849
+ + D A + LA+P L P+ PA + L
Sbjct: 2254 VN--LADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPA-------------VNLA 2298
Query: 850 PGRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSHPLLQDLAATRAARMDFHSQD 909
R+P A S T A+ P+ + P P +L R+A
Sbjct: 2299 GARTP---AALAALSLTGSGTPPTAANYPSSSRTPQA---PASANLVGPRSAHAT----- 2347
Query: 910 THLILKETETALAALEARLLSNSVDAECEGGS--TPRPPEDALSGDSDVDTASTVSLRSG 967
+ + + TA A A L S + G + +PR P A S S L
Sbjct: 2348 APVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSG--RTSPPLLDRA 2405
Query: 968 KSGPSPTTPQPLRAQKEMSPSP-------------PAAQDPGGTALVSAREQSSE---RQ 1011
+S P+ P R E +PSP P AQD + + SA S Q
Sbjct: 2406 RSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQ 2465
Query: 1012 HHPL-GPTDMGRGEPVRRSAIRRGHRPRGSLDWPSEERGPVLAHLPSSDVMASNHETPEA 1070
P+ G + G ++ H S+ P +P SDV E P +
Sbjct: 2466 TTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPG---------VPHSDV----GEPPAS 2512
Query: 1071 TGAGRLGSRRKPAAPPPSPAAREEQSRSSASSQKGPQALTRSNSLSTPRPTRASRLRRAR 1130
TGA ++P+A A+E +S SS+SS + + S+S S+
Sbjct: 2513 TGA------QQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSS------------- 2553
Query: 1131 LGDASDTEAADGERGSLGNPEPVGRPAAEQAKKLSRLDILAMPRKRAGSFTGTSDPEAAP 1190
+S + ++D E SL PV A KR S P AP
Sbjct: 2554 --SSSGSSSSDSEGSSL----PVQPEVA---------------LKRVPS------PTPAP 2586
Query: 1191 ARTSFSGRSVELCCASRKPTMAEARAVSRKAANTATTTGPRQPFSRARSGSARYTSTTQT 1250
GR E A RK R S ++++++++ S + S S+ +S++ +
Sbjct: 2587 KEAVREGRPPEPTPAKRK------RRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2640
Query: 1251 PRAGSSSRARSRAPGPR 1267
+ SSS PGP+
Sbjct: 2641 SSSSSSSSPSPAKPGPQ 2657
Score = 51.6 bits (122), Expect = 6e-06
Identities = 251/1237 (20%), Positives = 397/1237 (32%), Gaps = 171/1237 (13%)
Query: 130 RSEALPEHTPYCEASNPRPEKGDRRPGTEAASYRTPLYGQPSWWGEDDG-----STLPDA 184
RS + PE C + R G + RTPL GQ S G S P
Sbjct: 1498 RSPSSPELNNKC-LTPQRERSGSESSVDQKTVARTPL-GQRSRSGSSQELDVKPSASPQE 1555
Query: 185 QRQGEPYPE---RPKGPVQQDGELHGFRAPAEPQGCSFRREPSYFEIPTKETPQP----- 236
+ + + P+ + + P++Q S RR S K+ P+
Sbjct: 1556 RSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQ 1615
Query: 237 -----SQPPEVPAHEMPTKDAEAGGGGAAPVVQSHASFTIEFDDCSPGKMKIKDHITKFS 291
S P+ PA + + +G S + E P K + ++ S
Sbjct: 1616 SGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSS 1675
Query: 292 LRQRRPPGKEATPGEMVSAETKVADWLVQNDPSLLHRVGPGDDRHSTKSDLPVHTRTLKG 351
P K TP S+ ++ P L + S S +RT
Sbjct: 1676 ---PEPKTKSRTPPRRRSS---------RSSPELTRKARLSRRSRSASSSPETRSRTPPR 1723
Query: 352 HKHEDGTQSDSEDPLAKAASAAGVPLEASGEQVRLQRQIKRDPQELLHNQQAFVIEFFDE 411
H+ S +P K+ S+ AS + + + R P Q E
Sbjct: 1724 HRRSPSVSSP--EPAEKSRSSRR-RRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRRE 1780
Query: 412 DTPRKKRSQSFTHSPSGDPKADKRRGPTPADRDRPSVPAPVQAGGRSSGPQRAGSLKREK 471
T +R SG ++ RR R R + +G S P R S R
Sbjct: 1781 KTRTTRRRDR-----SGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQES-SRTS 1834
Query: 472 TEERLGSPSPASRTPARPFGSVGRRSRLAQDFMAQCLRESSPAARPSPEKVPPVLPAPLT 531
+ R G SRTP P RSR + + +SPA P++ +
Sbjct: 1835 SRRRRGR----SRTP--PTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRS 1888
Query: 532 PHGTSPVGPPTPPPAPTDPQLTKARKQEEDDSLSDAGTYTIETEAQDTEVEEARKMIDQV 591
TSPV + + +T+ R + +S + + T +R +
Sbjct: 1889 RSRTSPVSRRR---SRSRTSVTRRRSRSRASPVSRRRSRS-RTPPVTRRRSRSRTPTTRR 1944
Query: 592 FGVLESPELSRASSATFRPVIRGDRDESDDGGVAQRMALLQEFASRPLGAAPQAEHQGLP 651
+P ++R S + P + R S + +R ++ + P
Sbjct: 1945 RSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRR----------------RSRSRTSP 1988
Query: 652 VPGSPGGQKWVSRWASLADSYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERADS 711
V ++ SR + + S + R ++ R R R P LP +R+ S
Sbjct: 1989 VTR----RRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRS 2044
Query: 712 PAGPESSRRSGPGPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSRRR 771
+ RRS P + S + S S +S SD R P S R
Sbjct: 2045 RSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSS-SDRSRSATPPATRNHSGSR 2103
Query: 772 SPQEGPTWSRGRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPP 831
+P SR R PTP L R +PG E LG + P
Sbjct: 2104 TPPVALNSSRMSCFSRPSMSPTP-------------LDR--CRSPGMLEPLGSSRTPMSV 2148
Query: 832 ARD--GVYVSANGRMVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGPP---APGKPPHI 886
+ G + G + + PE + L + + A PP A G +
Sbjct: 2149 LQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARM 2208
Query: 887 SSHP---------------LLQDLAATRAARMDFHSQDTHLILKETETALAALEARLLSN 931
S P L + A AA M+ S T I TA+ ++R +
Sbjct: 2209 SQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAI----PTAVNLADSRTPAA 2264
Query: 932 SVDAECEGGSTPRPPEDALSGDSDVDTASTVSLRSGKSGPSPTTPQPLRAQKEMSPSPPA 991
+ T P D TA V+L ++ P L +P P A
Sbjct: 2265 AAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGART---PAALAALSLTGSGTP-PTA 2320
Query: 992 AQDPGGTALVSAREQSSERQHHPLGPTDMGRGEPVRRSAIRRGHRPRGSLDWPSEERGPV 1051
A P S+R + + +GP PV + R S P
Sbjct: 2321 ANYPS-----SSRTPQAPASANLVGPRSAHATAPVNIAGSRTA-AALAPASLTSARMAPA 2374
Query: 1052 L--AHLPSSDVMASNHETPEATGAGRLGSRRKPAAPPPSPA-AREEQSRSSASSQKGPQA 1108
L A+L S V S +E + L R + PP +P+ +R R+ + S + QA
Sbjct: 2375 LSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQA 2434
Query: 1109 LTRS------NSLSTPRPTRASRLRRARLGD---------------ASDTEAADGERGSL 1147
++S + +P P+ S R + A+ T +A G L
Sbjct: 2435 PSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGML 2494
Query: 1148 GNPEP------VGRPAAEQ-AKKLSRLDILAMPRKRAGSFTGTSDPEAAPARTSFSGRSV 1200
P P VG P A A++ S L L ++R S + +S ++ + +S S S
Sbjct: 2495 SVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSS 2554
Query: 1201 ELCCASR-------------------KPTMAEARAVSRKAANTATTTGPRQPFSRARSGS 1241
+S PT A AV T ++ S + S S
Sbjct: 2555 SSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSS 2614
Query: 1242 ARYTSTTQTPRAGSSSRARSRAPGPRDTDDDEEEPDP 1278
+ +S++ + + SSS + S + + P P
Sbjct: 2615 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSP 2651
Score = 51.2 bits (121), Expect = 8e-06
Identities = 262/1288 (20%), Positives = 404/1288 (31%), Gaps = 247/1288 (19%)
Query: 145 NPRPEKGDRRPGTEAASYRTPLYGQPSWWGEDDGSTLPDAQRQGEPYPER--------PK 196
+P PE+ P A TPL + +T P +Q P E PK
Sbjct: 351 SPSPERSSTGPEPPAP---TPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPK 407
Query: 197 GPVQQDGELHGFRAPAEPQGCSFRREPSYFEIPTKETPQPSQPPEVPAHEMPTKDAEAGG 256
P + +P PQ R S K P P E+ + PT + G
Sbjct: 408 SPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSS--PTSKNRSHG 465
Query: 257 GGAAPVVQSHASFTIEFDDCSP-----GKMKIKDHITKFSLRQRRPPGKEATPGEMVSAE 311
SH SP G+ + + + R R P + + +
Sbjct: 466 RAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRS 525
Query: 312 TKVADWLVQNDPSLLHRVGPGDDRHSTKSDLPVHTRTLKGHKHEDGTQ--SDSEDPLAKA 369
P R G R++ + R + H T+ S S P +
Sbjct: 526 RSPQRRGRSRSPQ---RPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRG 582
Query: 370 ASAAGVPLEA-------------SGEQVRLQRQIKRDPQELLHNQQAFVIEFFDEDTPRK 416
S + P S R R R P ++ V +P +
Sbjct: 583 RSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPAR 642
Query: 417 KRSQSFTHSPSGDPKADKRRGPTPADRDRPSVPAPVQAGGRSSG--PQRAGSLKREKTEE 474
+ +S + +P+ + + R TPA R R P + GRS P R G R +T
Sbjct: 643 RSGRSRSRTPA---RRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGR-SRSRTPR 698
Query: 475 RLGSPSPA--------SRTPARP--FGSVGRRSRLAQDFMAQCLRESSPAARPSP----- 519
R S S + SRTP R GS R ++ + SSP + S
Sbjct: 699 RGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRR 758
Query: 520 --------EKVPPVLPAPLTPHGTSPVGPPTPPPAPTDPQLTKARKQEEDDSLSDAGTYT 571
K L + G+SP P T R+ S A + T
Sbjct: 759 SRSLSSPRSKAKSRLSLRRSLSGSSP--------CPKQKSQTPPRRSRSGSSQPKAKSRT 810
Query: 572 IETEAQDTEVEEARKMIDQVFGVLESPELSRASSATFRPVIRGDRDESDDGGVAQRMALL 631
++ + ++ ++P SS++ P ++ G R +
Sbjct: 811 PPRRSRSSSSPPPKQKS-------KTPSRQSHSSSSPHPKVKS--------GTPPRQGSI 855
Query: 632 QEFASRPLGAAPQAEHQGLPVPGSPGGQKWVSRWASLADSYSDPGLTEDGLGRRGGEPEG 691
+PQA Q + + S +S DP L R G
Sbjct: 856 ---------TSPQANEQSV-----------TPQRRSCFESSPDPELKSRTPSRHSCS--G 893
Query: 692 SLPVRMRRRLP--QLPSERAD---------SPAGPESSRRSGPGPPELDSEQPSRLFGQE 740
S P R++ P Q PS + SP S S P P + S R
Sbjct: 894 SSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRR--SR 951
Query: 741 ELDPDS-----LSDASGSDGGRGPEPGVEPQDSRRRSPQ--------------EGPTWSR 781
+ P S L G P+ V+P+ R+S GP+ S
Sbjct: 952 SVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLS- 1010
Query: 782 GRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEG--------LGQTAQPSPPAR 833
G +SP P E + S + G L ++ GE L +Q SP R
Sbjct: 1011 GSKSP-CPQEKSKDSL-VQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHR 1068
Query: 834 DGVYVSANGRMVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSHPLLQ 893
+ + +S P R S E AS P S+ P+L+
Sbjct: 1069 SDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLK 1128
Query: 894 DLAATRAARMDFHSQDTHLILKETETALAALEARLLSNSVDAECEGGSTPRPP--EDALS 951
+ +R S + + + LE + + +T PP +D S
Sbjct: 1129 SGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFS 1188
Query: 952 G-------DSDV---DTASTVSLRSGKSGPSPTTPQ-----PLRAQ-KEMSPSPPAAQDP 995
+S + DT T +G SP T + P +Q +E+ +++P
Sbjct: 1189 PFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEP 1248
Query: 996 GGTAL-----------VSAREQSSERQHHPLGPTDMGRGEPVRRSAIRRGHRPRGSLDWP 1044
G L S E S E + P + + + ++++ P + W
Sbjct: 1249 AGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQS--QASLEAVEVPSMASSWG 1306
Query: 1045 SEERGPVLAHLPSSDVMASNHETP-EATGAGRLGSRRKPA-----------------APP 1086
P L +S + ++ +P E +G LG+
Sbjct: 1307 GPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETD 1366
Query: 1087 PSPAAREEQSRSS--ASSQKGPQALTRSN-----SLSTPRPTRASRL-RRARLGDASDTE 1138
PS +E+ +RSS +SS+ P A+ ++ S+S+P R R R AS E
Sbjct: 1367 PSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPE 1426
Query: 1139 AADGERGSLGNPEPVGRPAAEQAKKLSRLDILAMPRKRAGSFTGTSDPEAAPARTSFSGR 1198
DG P R R R+GS G D P+R S SG
Sbjct: 1427 MKDGL------PRTPSR------------------RSRSGSSPGLRDGSGTPSRHSLSGS 1462
Query: 1199 SVELCCASRKPTMAEARAVSRKAANTATTTGPRQPFSRARSGSARYTS----TTQTPRAG 1254
S + R P+ + S P+ P R+RS S+ + T Q R+G
Sbjct: 1463 SPGMKDIPRTPSRGRSECDSSPEPKAL----PQTPRPRSRSPSSPELNNKCLTPQRERSG 1518
Query: 1255 SSS----RARSRAP-GPRDTDDDEEEPD 1277
S S + +R P G R +E D
Sbjct: 1519 SESSVDQKTVARTPLGQRSRSGSSQELD 1546
Score = 50.4 bits (119), Expect = 1e-05
Identities = 200/908 (22%), Positives = 318/908 (35%), Gaps = 147/908 (16%)
Query: 410 DEDTPRKKRSQSFTHSP-----SGDPKADKRRGPTPADRDRPSVPAPVQAGGRSSGPQ-- 462
+E + +R F SP S P G +P R + S P P Q+ RSS PQ
Sbjct: 861 NEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPP-RVKSSTP-PRQSPSRSSSPQPK 918
Query: 463 -RAGSLKREKTEERLGSPSPA---SRTPARPFGSVGRRSRLAQDFMAQCLRESSPAARPS 518
+A R+++ SPSP+ SRT R SV S + ++ L S + S
Sbjct: 919 VKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVE----SRLLPRYSHSGSSS 974
Query: 519 PE-KVPPVLPAPLTPHGTSPVGPPTPPPAPTDPQLTKARKQEEDDSLSDAGTYTIETEAQ 577
P+ KV P P + G+ P P P SLS + + + +++
Sbjct: 975 PDTKVKPETPPRQSHSGSISPYPKVKAQTPPGP------------SLSGSKSPCPQEKSK 1022
Query: 578 DTEVEEARKMIDQVFGVLESPELSRASSATFRPVIRGDRDESDDGGVAQRMALLQEFASR 637
D+ V+ + GV S + ++G S D R
Sbjct: 1023 DSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPD--------------HR 1068
Query: 638 PLGAAPQAEHQGLPVPGSPGGQKWVSRWASLADSYSDPGLTEDGLGRRGGEPEGSLPVRM 697
++P+ P + S + P +GG S PV
Sbjct: 1069 SDTSSPEVRQSHSESPSLQ------------SKSQTSP---------KGGRSRSSSPVTE 1107
Query: 698 RRRLPQLPSERADSPAGPESSRRSGPGPPELDSEQPSRLFGQEELDPDSLSDASGSDGGR 757
+ +R + A P P S+ S +D +SL S +
Sbjct: 1108 LASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSS----YPTVDSNSLLGQSRLETAE 1163
Query: 758 GPEPGVEPQDSRRRSPQEGPTWSRGRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPG 817
E P PQE T S PR + +P F + D+ +++ + L P
Sbjct: 1164 SKEKMALP-------PQEDATAS----PPRQKDKFSP--FPVQDRPESSLVFKDTLRTP- 1209
Query: 818 DGEGLGQTAQPSPPARDGVYVSANGRMVIQLRPGRSPEPDGPAPAFLR---QESFTKEPA 874
E G + P ++ +++ + +S EP G + L +E T
Sbjct: 1210 PRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFE 1269
Query: 875 SGPPAPGKPPHISSHPLLQDLAATRAARMDF-------------HSQDTHLILKETETAL 921
S P +P + Q A+ A + H + ++ L+E
Sbjct: 1270 SSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFG- 1328
Query: 922 AALEARLLSNSVDAECEGGSTPRPPEDALSGD--SDVDTASTVSLR---SGKSGPSPTTP 976
+ LE R S + E G + ED L+G + ++T ++ ++ + SG S +
Sbjct: 1329 SPLEFRN-SGPLGTEMNTGFSSEVKED-LNGPFLNQLETDPSLDMKEQSTRSSGHSSSEL 1386
Query: 977 QPLRAQKEMSPSPPAAQDPGGTALVSAREQSSERQHHPLGPTDMGRGEPVRRSAIRRGHR 1036
P +K S + P A+ R S ER P +M G P S R
Sbjct: 1387 SPDAVEKAGMSSNQSISSPVLDAV--PRTPSRERSSSASSP-EMKDGLPRTPSRRSRSGS 1443
Query: 1037 PRGSLDWPSEERGPVLAHLPSSDVMASNHETPEATGAGRLGSRRKPAAPPPSPAAREEQS 1096
G D L+ SS M TP + G S +P A P +P R S
Sbjct: 1444 SPGLRDGSGTPSRHSLSG--SSPGMKDIPRTP-SRGRSECDSSPEPKALPQTPRPR---S 1497
Query: 1097 RSSASSQKGPQALT----RSNSLSTPRPTRASRL---RRARLGDASDTEAADGERGSLGN 1149
RS +S + + LT RS S S+ +R +R+R G + + + + S
Sbjct: 1498 RSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDV----KPSASP 1553
Query: 1150 PEPVGRPAAEQAKKLSRLDILAMPRKRAGSFTGTSDPEAAPARTSFSGRSVELCCASRKP 1209
E ++ +K +R + R R+GS R S SG S E+ KP
Sbjct: 1554 QERSESDSSPDSKAKTRTPL--RQRSRSGSSPEVDSKSRLSPRRSRSGSSPEV---KDKP 1608
Query: 1210 TMAEARAVSRKAANTATTTGPRQPFSRARSGSARYTSTTQTPRAGSSSRARSRAP-GPRD 1268
RA R + + ++ P+ P RA + R+GSSS+ R +P G
Sbjct: 1609 -----RAAPRAQSGSDSSPEPKAPAPRA---------LPRRSRSGSSSKGRGPSPEGSSS 1654
Query: 1269 TDDDEEEP 1276
T+ E P
Sbjct: 1655 TESSPEHP 1662
Score = 49.3 bits (116), Expect = 3e-05
Identities = 180/873 (20%), Positives = 296/873 (33%), Gaps = 111/873 (12%)
Query: 413 TPRKKRSQSFTHSPSGDPKADKRRGPTPADRDRPSVPAPVQAGGRSSGPQRAGSLKREKT 472
TP R +S + +P+ ++ R P R R P + RS R + R ++
Sbjct: 1927 TPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRS----RTSPITRRRS 1982
Query: 473 EERLGSPSPASRTPARPFGSVGRRSRLAQDFMAQCLRESSPAARPSPEKVPPVLP----- 527
R SP R+ +R RRSR R S R S + PP +
Sbjct: 1983 RSRT-SPVTRRRSRSRTSPVTRRRSRS---------RTSPVTRRRSRSRTPPAIRRRSRS 2032
Query: 528 -APLTPHGTSPVGPP----------TPPPAPTDPQLTKA----RKQEEDDSLSDAGTYTI 572
PL P S P TP A LT++ R++ S SD
Sbjct: 2033 RTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSAT 2092
Query: 573 ETEAQDTEVEEARKMIDQVFGVLESPELSRASSATFRPVIRGDRDESDD-----GGVAQR 627
++ + L S +S S + P DR S G
Sbjct: 2093 PPATRNHSGSRTPPV------ALNSSRMSCFSRPSMSPTPL-DRCRSPGMLEPLGSSRTP 2145
Query: 628 MALLQEFASRPL-GAAPQA-EHQGLPVPGSPGGQKWVSRWA--SLADSYSDPGLTEDGLG 683
M++LQ+ + G P+ +HQ VP + + SL + P ++ GL
Sbjct: 2146 MSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLA 2205
Query: 684 RRGGEPEGSLPVRMRRRLP------QLPSERADSPAGPESSRRSGPGPPEL---DSEQPS 734
R + +P+ R P ++P+ A + A +S R+ P + DS P+
Sbjct: 2206 ARMSQVPAPVPLMSLRTAPAANLASRIPA--ASAAAMNLASARTPAIPTAVNLADSRTPA 2263
Query: 735 RLFGQEELDPDSLSDASG---SDGGRGPEPGVEPQDSRRRSPQEG---------PTWSRG 782
P + S +D P V +R + PT +
Sbjct: 2264 AAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANY 2323
Query: 783 RRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSANG 842
S R P P A+ +G ++ A AP + G +TA PA +
Sbjct: 2324 PSSSRTPQAPASANL-VGPRSAHAT-------APVNIAG-SRTAAALAPAS-----LTSA 2369
Query: 843 RMVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSHP-LLQDLAATRAA 901
RM L P P A+ R T P PP S + + A + ++
Sbjct: 2370 RMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSS 2429
Query: 902 RMDFHSQDTHLILKETETALAALEARLLSNSVDAECEGGSTPRPPEDALSGDSDVDTAST 961
RM + L+ + + + + S + +TP +LS + T S+
Sbjct: 2430 RMG-QAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQ--TTPVAGSQSLSSGAVATTTSS 2486
Query: 962 VSLRSGK-SGPSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAREQSSERQHHPLGPTDM 1020
+G S P+P P + P+ AQ P A A + + ER+ +
Sbjct: 2487 AGDHNGMLSVPAPGVPH---SDVGEPPASTGAQQPSALA---ALQPAKERRSSSSSSSSS 2540
Query: 1021 GRGEPVRRSAIRRGHRPRGSLDWPSEERGPVLAHLPSSDVMASNHETPEATGAGRLGSRR 1080
S+ S S+ G L P + TP A R G
Sbjct: 2541 SSSSSSSSSSSSSSSSGSSS----SDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGR-- 2594
Query: 1081 KPAAPPPSPAAREEQSRSSASSQKGPQALTRSNSLSTPRPTRASRLRRARLGDASDTEAA 1140
P P+PA R+ +S SS+SS + + S+S S+ + +S + +S + +
Sbjct: 2595 ---PPEPTPAKRKRRSSSSSSSSSSSSS-SSSSSSSSSSSSSSSSSSSSSSSSSSSSSPS 2650
Query: 1141 DGERGSLGNPEPVG---RPAAEQAKKLSRLDILAMPRKRAGSFTGTSDPEAAPARTSFSG 1197
+ G P+P P E+ + R I ++ R+ S++ +P +
Sbjct: 2651 PAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQ 2710
Query: 1198 RSVELCCASRKPTMAEARAVSRKAANTATTTGP 1230
+S SR+ ++R+ S K + P
Sbjct: 2711 QSSSSERGSRRGQRGDSRSPSHKRRRETPSPRP 2743
Score = 48.1 bits (113), Expect = 6e-05
Identities = 95/439 (21%), Positives = 154/439 (35%), Gaps = 46/439 (10%)
Query: 849 RPGRSPEPDGPAP-AFLRQESFTKEPASGPPAPGKPPHISSHPLLQDLAATRAARMDFHS 907
R + P P+ P P + +R+ S ++ P P K + ++ R R
Sbjct: 158 REAKQPAPEPPKPYSLVRESSSSRSPT---PKQKKKKKKKDRGRRSESSSPRRERKKSSK 214
Query: 908 QDTHLILKETETAL---AALEARLLSNSVDAECEGGSTPRPPEDALSGDSDVDTASTVSL 964
+ H E++ +++ S + +TP P + D+AS+
Sbjct: 215 KKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDT 274
Query: 965 RSGKSGPSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAREQSSERQHHPLGPTDMGRGE 1024
+S S A SPSP + + G A S E + P P
Sbjct: 275 SRSRSR-SAAAKTHTTALAGRSPSPASGRRGEGDAPFS--EPGTTSTQRPSSP------- 324
Query: 1025 PVRRSAIRRGHRPRGSLDWPSEERGPVLAHLPSSDVMASNHETPEATG--AGRLGSRRKP 1082
+A ++ P D +E+ PS + ++ E P T A R G +P
Sbjct: 325 ---ETATKQPSSPYEDKDKDKKEKSATRPS-PSPERSSTGPEPPAPTPLLAERHGGSPQP 380
Query: 1083 AAP---------PPSPAAREEQSRSSASSQKGPQALTRSNSLSTPRPTRASRLRRARLGD 1133
A PPS A+ S +K PQ+ + +S +P+PT+ SR +
Sbjct: 381 LATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPES 440
Query: 1134 ASDTEAADGERGSLGNPEPVGRP--AAEQAKKLSRLDILAMPRKR--AGSFTGTSDPEAA 1189
A R +P R A++ K S M R R A + G S
Sbjct: 441 PKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTP 500
Query: 1190 PARTSFSGRSVELCCASRKPTMAEARAVSRKAANTATTTGPRQP-FSRARSGSARYTSTT 1248
R RS + R+ A+ SR + P++P +SR+R+ R S
Sbjct: 501 TKRGHSRSRSPQW----RRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRS-- 554
Query: 1249 QTPRAGSSSRARSRAPGPR 1267
R+ R+ SR+P R
Sbjct: 555 ---RSARRGRSHSRSPATR 570
Score = 44.7 bits (104), Expect = 7e-04
Identities = 147/729 (20%), Positives = 237/729 (32%), Gaps = 121/729 (16%)
Query: 413 TPRKKRSQSFTHSPSGDPKADKRRGPTPADRDRPSVPAPVQAGGRSSGPQRAGSLKREKT 472
T R ++ T PS P DK + RPS P+P ++ S+GP+
Sbjct: 318 TQRPSSPETATKQPSS-PYEDKDKDKKEKSATRPS-PSPERS---STGPEPPAPTPL-LA 371
Query: 473 EERLGSPSPASRTPARPFGSVGRRSRLAQDFMAQCLRESSPAARPSPEKVPPVLPAPLTP 532
E GSP P + TP ++Q A P+ ++ PP P L
Sbjct: 372 ERHGGSPQPLATTP-----------------LSQEPVNPPSEASPTRDRSPPKSPEKLPQ 414
Query: 533 HGTSPVGPPTPPPAPTDPQLTKARKQEEDDSLSDAGTYTIETEAQDTEVEEARKMIDQVF 592
+S PP+P P + + E G++
Sbjct: 415 SSSSESSPPSPQPTKVSRHASSS--PESPKPAPAPGSHR--------------------- 451
Query: 593 GVLESPELSRASSATFRPVIRGDRDESDDGGVAQRMALLQEFASRPLGAA-----PQAEH 647
E+S + ++ R R RD+S ++RM + A+ G + + H
Sbjct: 452 ------EISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGH 505
Query: 648 QGLPVP---GSPGGQKW----VSRWASLADSYSDPGLTEDGLGRRGGEPEGSLPVRMRRR 700
P S Q+W + + S PG + +R G + R R
Sbjct: 506 SRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSR 565
Query: 701 LPQLPS-ERADSPAGPESSRRSGPGPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGP 759
P R+ +PA SR P S P+R + + + GR
Sbjct: 566 SPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSR---------TPARRGRSR 616
Query: 760 EPGVEPQDSRRRSPQEGPTWSR--GRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPG 817
+ SR RSP + SR RRS R+ TPA A R P
Sbjct: 617 SRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSR-TPARRGRSRSRTPARRGRSRSRTPA 675
Query: 818 DGEGLGQTAQPSPPARDGVYVSANGRMVIQ--LRPGRSPEPDGPAPAFLRQESFTKEPAS 875
G ++ P+ R GR + +R GRS + + S
Sbjct: 676 RRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRS-----------HSRTPQRRGRS 724
Query: 876 GPPAPGKPPHISSHPLLQDLAATRAARMDFHSQDTHLILKETETALAALEARLLSNSVDA 935
G + K +S + ++ + S+ + + A + L R S S +
Sbjct: 725 GSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLR-RSLSGSS 783
Query: 936 ECEGGSTPRPPEDALSGDSDVDTASTVSLRSGKSGPSPTTPQPLRAQKEMSPSPPAAQDP 995
C + PP + SG S S R +S SP QK +PS
Sbjct: 784 PCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPP-----KQKSKTPS------- 831
Query: 996 GGTALVSAREQSSERQHHPLGPTDMGRGEPVRRSAIRRGHRPRGSLDWPSEERGPVLAHL 1055
R+ S HP + G P R+ +I P+ + + +R
Sbjct: 832 --------RQSHSSSSPHP----KVKSGTPPRQGSIT---SPQANEQSVTPQRRSCFESS 876
Query: 1056 PSSDVMASNHETPEATGAGRLGSRRKPAAPPPSPAAREEQSRSSASSQKGPQALTRSNSL 1115
P ++ + +G+ R K + PP +R + + P+ + S S
Sbjct: 877 PDPELKSRTPSRHSCSGSS--PPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGS- 933
Query: 1116 STPRPTRAS 1124
S+P P+R +
Sbjct: 934 SSPSPSRVT 942
Score = 43.1 bits (100), Expect = 0.002
Identities = 99/448 (22%), Positives = 141/448 (31%), Gaps = 93/448 (20%)
Query: 684 RRGGEPEGSLPVRMRRRLPQLPSERADSPAGPESSRRSGPGPPELDSEQPSRLFGQEELD 743
R G L R R R P P+ P SR + P PS GQ
Sbjct: 2392 RVSGRTSPPLLDRARSRTP---------PSAPSQSRMTSERAPS-----PSSRMGQA--- 2434
Query: 744 PDSLSDASGSDGGRGPEPGVEPQDSRRRSPQEGPTWSRGRRSPRAPGEPTPASFFIGDQN 803
P D R P P SR Q P S A T ++ GD N
Sbjct: 2435 PSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSA---GDHN 2491
Query: 804 GDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSANGRMVIQLRPGRSPEPDGPAPAF 863
G L+ P G +P PA G + + + RS + +
Sbjct: 2492 G-------MLSVPAPGVPHSDVGEP--PASTGAQQPSALAALQPAKERRSSSSSSSSSSS 2542
Query: 864 LRQESFTKEPASGPPAPGKPPHISSHPLLQDLAATRAARMDFHSQDTHLILKETETALAA 923
S + +S + SS P+ ++A R ++ + E A
Sbjct: 2543 SSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAK 2602
Query: 924 LEARLLSNSVDAECEGGSTPRPPEDALSGDSDVDTASTVSLRSGKSGPSPTTPQPLRAQK 983
+ R S+S + S+ + S S ++S+ S S S PSP P P K
Sbjct: 2603 RKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS-SSSSSSPSPAKPGPQALPK 2661
Query: 984 EMSPSPPAAQDPGGTALVSAREQSSERQHHPLGPTDMGRGEPVRRSAIRRGHRPRGSLDW 1043
SP P PG RR PR +D
Sbjct: 2662 PASPKKP---PPGE----------------------------------RRSRSPRKPIDS 2684
Query: 1044 PSEERGPVLAHLPSSDVMASNHETPEATGAGRLGSRRKPAAPPPSPAAREEQSRSS-ASS 1102
+ R L++ P RR+P+ P P+ R++QS SS S
Sbjct: 2685 LRDSRS--LSYSPV--------------------ERRRPS---PQPSPRDQQSSSSERGS 2719
Query: 1103 QKGPQALTRSNSLSTPRPTRASRLRRAR 1130
++G + +RS S R T + R R R
Sbjct: 2720 RRGQRGDSRSPSHKRRRETPSPRPMRHR 2747
Score = 42.7 bits (99), Expect = 0.003
Identities = 69/316 (21%), Positives = 120/316 (37%), Gaps = 31/316 (9%)
Query: 1075 RLGSRRKPAAPPPSPAAREEQSRSSAS------SQKGPQALTRSNSLSTPRPTRASRLRR 1128
R ++PA PP P + +S SS S +K + R + S+PR R ++
Sbjct: 156 RAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKK 215
Query: 1129 ARLGDASDTEAADGERGSLGNPEPVG-RPAAEQAKKLSRLDILAMPRKRAGSFT-----G 1182
+ S++E+ + S P P R + ++ +K SR A +RA T
Sbjct: 216 KK--HRSESESKKRKHRS---PTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSAS 270
Query: 1183 TSDPEAAPARTSFSGRSVELCCASRKPTMAEARAVSRKA----ANTATTTGPRQPFSRAR 1238
+SD + +R S + ++ A R P+ A R A T +T P P + +
Sbjct: 271 SSDTSRSRSR-SAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATK 329
Query: 1239 SGSARYTSTTQTPRAGSSSRARSRAPGPRDTDDDEEEPDPYGFIVQTAEIAEIARLSQTL 1298
S+ Y + + S++R +P P + E P P T +AE S
Sbjct: 330 QPSSPYEDKDKDKKEKSATRP---SPSPERSSTGPEPPAP------TPLLAERHGGSPQP 380
Query: 1299 VKDVAILAQEIHDVAGDGDTLGSSEPAHSASLSNMPSTPASTISAREELVQRIPEASLNF 1358
+ + + ++ + T S P L S+ +S S + V R +S
Sbjct: 381 LATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPES 440
Query: 1359 QKVPPGSLNSRDFDQN 1374
K P + R+ +
Sbjct: 441 PKPAPAPGSHREISSS 456
Score = 32.0 bits (71), Expect = 4.8
Identities = 56/270 (20%), Positives = 86/270 (31%), Gaps = 67/270 (24%)
Query: 323 PSLLHRVGPGDDRHSTKSDLPVHTRTLKGHKHEDGTQSDSEDPLAKAASAAGVPLEASGE 382
PS L + P +R S+ S + S S + ++ ++ E S
Sbjct: 2518 PSALAALQPAKERRSSSSS---------SSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSL 2568
Query: 383 QVRLQRQIKRDPQELLHNQQAFVIEFFDEDTPRKKRSQSFTHSPSGDPKADKRRGPTPAD 442
V+ + +KR P TP K + P P KRR + +
Sbjct: 2569 PVQPEVALKRVPSP----------------TPAPKEAVREGRPPEPTPAKRKRRSSSSSS 2612
Query: 443 RDRPSVPAPVQAGGRSSGPQRAGSLKREKTEERLGSPSPASRTPARPFGSVGRRSRLAQD 502
S + + SS + S + SPSPA P
Sbjct: 2613 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGP---------------- 2656
Query: 503 FMAQCLRESSPAARPSPEKVPPVLPAPLTPH------------GTSPV--GPPTPPPAPT 548
Q L + + SP+K PP +P SPV P+P P+P
Sbjct: 2657 ---QALPKPA-----SPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPR 2708
Query: 549 DPQLTK----ARKQEEDDSLSDAGTYTIET 574
D Q + +R+ + DS S + ET
Sbjct: 2709 DQQSSSSERGSRRGQRGDSRSPSHKRRRET 2738
>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
Length = 2663
Score = 67.8 bits (164), Expect = 8e-11
Identities = 203/909 (22%), Positives = 292/909 (32%), Gaps = 173/909 (19%)
Query: 353 KHEDGTQSDSEDPLAKAASAAGV-PLEASGEQVRLQRQ--------IKRDPQELLHNQQA 403
K +DG + + DP+ + V P + G++ R+ + + +L +
Sbjct: 1533 KFKDGAEKEKGDPVKMSNGNDKVAPSKDPGKKDARPREKLLGDGDLMMTSFERMLSQKDL 1592
Query: 404 FVIEFFDEDTPRKKRSQSFTHSPSGDPKADKRRGPTPADRDRP-SVPAPVQAGGRSSGPQ 462
+ E R K+ + H SGDPK ++ P R + +PA P
Sbjct: 1593 EIEERHKRHKERMKQMEKLRHR-SGDPKLKEKAKPADDGRKKGLDIPA-------KKPPG 1644
Query: 463 RAGSLKREKTEERLGSPSPASRTPARPFGSVGRRSRLAQDFMAQCLRESSPAARPSPEKV 522
K +K +E P PA+ P + LA M +
Sbjct: 1645 LDPPFKDKKLKESTPIP-PAAENKLHPASGADSKDWLAGPHMKE---------------- 1687
Query: 523 PPVLPAPLTPHGTSPVGPPTPPPAPT---------DPQLTKARKQEEDDSLSDAGTYTIE 573
VLPA P + P G PTP + P+ + D + D
Sbjct: 1688 --VLPASPRPDQSRPTGVPTPTSVLSCPSYEEVMHTPRTPSCSADDYADLVFDCADSQHS 1745
Query: 574 TEAQDTEVEEARKMIDQVFGVLESPELSRASSATFRP------------VIRGDRDESDD 621
T F V S AS A RP + R +E
Sbjct: 1746 TPVPTAPTSACSPSFFDRFSVASSGLSENASQAPARPLSTNLYRSVSVDIRRTPEEEFSV 1805
Query: 622 GGVAQRMALLQEFASRPLGAAPQAEHQGLPVPGSPGGQKWVSRWASLADSYSDP--GLTE 679
G R + +S P E + P+P P ++A L+ Y P GL
Sbjct: 1806 GDKLFRQQSVPAASSYDSPMPPSMEDRA-PLPPVP-----AEKFACLSPGYYSPDYGLPS 1859
Query: 680 DGLGRRGGEPEGSLPVRMRRRLPQLPSERADSPAGPESSRRSGPGP-PELDSEQPSRLFG 738
+ P + V SP G SS ++ P P P + PS L G
Sbjct: 1860 PKVDALHCPPAAVVTV-------------TPSPEGVFSSLQAKPSPSPRAELLVPS-LEG 1905
Query: 739 QEELDPDSLSDASGSDGGRGPEPG-VEPQDSRRRSPQEGPTWSRGRRSP---RAPGEPTP 794
D D+ D + PEP +EP D EGP + P P E
Sbjct: 1906 ALPPDLDTSEDQQATAAIIPPEPSYLEPLD-------EGPFSAVITEEPVEWAHPSEQAL 1958
Query: 795 ASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQ--PSPPAR----DGVYVSANGRMVIQL 848
AS IG S P++ P + L ++ Q P P R D ++ +A G
Sbjct: 1959 ASSLIGG------TSENPVSWPVGSDLLLKSPQRFPESPKRFCPADPLHSAAPGPFSASE 2012
Query: 849 RPGRSPEPDGPAPAFLR---------QESFTKEPA---SGPPAPGKPPHISSHPLLQDLA 896
P +P P PAP L ++ PA + AP PP +
Sbjct: 2013 APYPAP-PASPAPYALPVAEPGLEDVKDGVDAVPAAISTSEAAPYAPPS-GLESFFSNCK 2070
Query: 897 ATRAARMDFHSQDTHLILKETETALAALEARLLSNSVDAECEGGSTPRPPEDALSGDSDV 956
+ A +D + + AL LE L S G P P DA +G D
Sbjct: 2071 SLPEAPLDVAPEPACVAAVAQVEALGPLENSFLDGSRGLSHLGQVEPVPWADAFAGPEDD 2130
Query: 957 DTASTVSL-------RSGKSGPSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSARE---- 1005
SL + G + + L +EM P P + G + V A E
Sbjct: 2131 LDLGPFSLPELPLQTKDAADGEAEPVEESLAPPEEMPPGAPGVINGGDVSTVVAEEPPAL 2190
Query: 1006 ---QSSER-----QHHPLG-----------------PTDMGRGEP---VRRSAIRRGHRP 1037
Q+S R + P G P + RG+P V + + RP
Sbjct: 2191 PPDQASTRLPAELEPEPSGEPKLDVALEAAVEAETVPEERARGDPDSSVEPAPVPPEQRP 2250
Query: 1038 RGSLDWPSEERGPVLAHLPSSDVMASN--HETPEATGAG-----RLGSRRKPAAPPPSPA 1090
GS D +E GP A L + D A N + A GAG PA PP
Sbjct: 2251 LGSGDQGAEAEGPPAASLCAPDGPAPNTVAQAQAADGAGPEDDTEASRAAAPAEGPPGGI 2310
Query: 1091 ARE-EQSRSSASSQKGPQALTRSNSLSTPRPTRASRLRRARLGDASDTEAADGERGSLGN 1149
E + + +A + K P+ P R +R R L + S E+
Sbjct: 2311 QPEAAEPKPTAEAPKAPRV--------EEIPQRMTRNRAQMLANQSKQGPPPSEKECAPT 2362
Query: 1150 PEPVGRPAA 1158
P PV R A
Sbjct: 2363 PAPVTRAKA 2371
>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
[Homo sapiens]
Length = 1412
Score = 65.1 bits (157), Expect = 5e-10
Identities = 128/546 (23%), Positives = 189/546 (34%), Gaps = 130/546 (23%)
Query: 815 APGDGEGLGQTAQPSPPARDGVYVSANGRMVIQLRPGRSPEPDGPAPAFLRQESFTKEPA 874
A + E G+T P A G+ V L G+SP A S T+E
Sbjct: 125 AKAETEKAGKTGNSMPHP-------ATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEG 177
Query: 875 SGPP--APGKPPHISSHPLLQDLAATRAARMDFHSQDTHLILKETETALAALEARLLSNS 932
S P A KP +S A + D S+DT ET+ + A E L +
Sbjct: 178 SVPAFGAAAKPGMVS------------AGQADSSSEDTSSSSDETDVEVKASEKILQVRA 225
Query: 933 VDAECEG----GSTPRPPEDA---------------------LSGDSDVDTASTVSL--- 964
A +G G+TP PP A S DS+ +T + +L
Sbjct: 226 ASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQA 285
Query: 965 -RSGKSGP--SPTTPQPLRAQKEMSPSPPAAQDPGGTAL---------VSAREQSSERQH 1012
SGK+ + + P +K +P+PP P S+ E+S +
Sbjct: 286 KASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEE 345
Query: 1013 HPLGPTDMGRGEPVRRSAIRRGHRPR-GSLDWPSEERGPVLAHL----PSSDVMASNHET 1067
P G+ VR ++ PR G+ P + GP A + D +S+ E+
Sbjct: 346 APAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEES 405
Query: 1068 -------------------------PEAT-GAGRLGSRRKPAAP----PPSPAAR----E 1093
P +T G G LG P P P +P+A+ E
Sbjct: 406 DSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWE 465
Query: 1094 EQSRSSASSQKGPQALTRSNSLSTPRPTRASRLRRARLGDASDTEAADGERGSLGNPEPV 1153
E S SS+ S+S PT + + LG+ +A + G P+
Sbjct: 466 EDSESSSEES--------SDSSDGEVPTAVAPAQEKSLGNI--LQAKPTSSPAKGPPQKA 515
Query: 1154 GRPAAEQAKKLSRLDILAMPRKRAGSFTGTSDPEAAPARTSFSGRSVELCCASRKPTM-- 1211
G P A Q K +D + + S +D E APA + A KP +
Sbjct: 516 G-PVAVQVKAEKPMDNSESSEESSDS----ADSEEAPA---------AMTAAQAKPALKI 561
Query: 1212 AEARAVSRKAANTATTTGPRQPFSRARSGSARYTSTTQTPRAGSSSRARSRAPGPRDTDD 1271
+ +A +K T TT + R + + R T +P AGSS P +
Sbjct: 562 PQTKACPKK---TNTTASAKVAPVRVGTQAPRKAGTATSP-AGSSPAVAGGTQRPAEDSS 617
Query: 1272 DEEEPD 1277
EE D
Sbjct: 618 SSEESD 623
Score = 65.1 bits (157), Expect = 5e-10
Identities = 175/876 (19%), Positives = 293/876 (33%), Gaps = 124/876 (14%)
Query: 353 KHEDGTQSDSEDPLAKAASAAGVPLEASGEQVRL-QRQIKRDPQELLHNQQAFVIEFFDE 411
K E+ +QS SE+ ++ + A QVR K P++
Sbjct: 328 KREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGA------------A 375
Query: 412 DTPRKKRSQSFTHSPSGDPKADKRRGPTPADRDRPSVPA----PVQAGGRSSGPQRAGSL 467
P +K + G + D R +D DR ++ A V+ G+S + A ++
Sbjct: 376 PAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTM 435
Query: 468 KREKTEERLGSPSPASRTPARPFGSVGRRSRLAQDFMAQCLRESS----PAARPSPEKV- 522
+ G P PA P VG+ ++ + S A P+ EK
Sbjct: 436 GMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSL 495
Query: 523 -------PPVLPAPLTPHGTSPVGPPTPPPAPTDPQLTKARKQEEDDSLSDAGTYTI--- 572
P PA P PV P D + + DS T
Sbjct: 496 GNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQA 555
Query: 573 -------ETEA--QDTEVEEARKMIDQVFGVLESPELSRASS----------ATFRPVIR 613
+T+A + T + K+ G + A+S T RP
Sbjct: 556 KPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAED 615
Query: 614 GDRDESDDGGVAQRMALLQEFASRPLGAAPQAEHQGLPVPGSPG--------GQKWVSRW 665
E D + + ++ +G Q + +PV GS G G+ +
Sbjct: 616 SSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVT 675
Query: 666 ASLADSYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERADSPAGPESSRR--SGP 723
A+ D +E+ E + P +++ + + ++ + A S++ S P
Sbjct: 676 QVKAEKQEDSESSEE---ESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAP 732
Query: 724 GPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPE--PGVEPQDSRRRSPQEGPTWSR 781
G + Q + ++ P + + + RGP P V + Q GP
Sbjct: 733 GKVVTAAAQAKQR-SPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDS 791
Query: 782 GRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSAN 841
G + E + +G R LA + G A P+PP + G +
Sbjct: 792 GSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKG--AAPTPPGKTGPSAAQA 849
Query: 842 GRMVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSHPLLQDLAAT-RA 900
G+ + DG APA + K P P ++ P A+T R
Sbjct: 850 GKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRK 909
Query: 901 ARMDFHSQDTHLILKETETALAALEARLLSNSVDAECEGGSTPR-PPEDALSGDSDVDTA 959
AR + + E E + A + + + PR P+ +++G S +
Sbjct: 910 ARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKES 969
Query: 960 STVSLRSGKSGPSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAREQSSERQHHPLGPTD 1019
S +S GK P T ++S PA+ AL +++SE Q
Sbjct: 970 SRIS--DGKKQEGPAT--------QVSKKNPASLPLTQAALKVLAQKASEAQ-------- 1011
Query: 1020 MGRGEPVRRSAIRRGHRPRGSLDWPSEERGPVLAHLPSSDVMASNHETPEATGAGRLGSR 1079
PV R+ PS + LP++ ++ + +A G +L
Sbjct: 1012 ----PPVARTQ-------------PSSGVDSAVGTLPATSPQST---SVQAKGTNKL--- 1048
Query: 1080 RKPAAP--------PPSPAAREEQSRSSASSQ---KGPQALTRSNSLSTPRPTRASRLRR 1128
RKP P P S E+ S SS+ S+ +GPQ +++L P P+R L
Sbjct: 1049 RKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVE 1108
Query: 1129 ARLGDASDTEAADGERGSL-GNPEPVGRPAAEQAKK 1163
++S+ + + L G P PA QA K
Sbjct: 1109 ETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASK 1144
Score = 59.7 bits (143), Expect = 2e-08
Identities = 209/1025 (20%), Positives = 350/1025 (34%), Gaps = 221/1025 (21%)
Query: 410 DEDTPRKKR--------SQSFTHSPSGDPKADKRRG--PTPADRDRPSVPAPVQAGGRSS 459
+E+TP K S + S K R+G P P + P+V A QAG R
Sbjct: 273 EEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAV-AKAQAGKREE 331
Query: 460 GPQRAGSLKREKTEERLGSPSPASRTPARPFGSVGRRSRLAQDFMAQCLRESSPAARPSP 519
Q + S + + EE P+ + P +R +S A+ SP
Sbjct: 332 DSQ-SSSEESDSEEEAPAQAKPSGKAPQ--------------------VRAASAPAKESP 370
Query: 520 EKVPPVLPAPLTPHGTSPVGPPTPPPAPTDPQLTKARKQEEDDSLSDAGTYTIETEAQDT 579
K G +P P PA Q+ KQEED S +E D+
Sbjct: 371 RK------------GAAPAPPRKTGPAAAQVQV---GKQEEDSRSS--------SEESDS 407
Query: 580 EVEEARKM-IDQVFGVLESPELSRASSATFRPVIRGDRDESDDGGVAQRMALLQEFASRP 638
+ E M QV + +SP++ AS+ P+ +G
Sbjct: 408 DREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKG------------------------ 443
Query: 639 LGAAPQAEHQGLPVPGSPGGQKWVSRWASLADSYSDPGLTEDGLGRRGGEPEGSLPVRMR 698
G P G P +P Q V +W ++S S+ E G P P + +
Sbjct: 444 AGPVP----PGKVGPATPSAQ--VGKWEEDSESSSE----ESSDSSDGEVPTAVAPAQEK 493
Query: 699 RRLPQLPSERADSPA-GPESSRRSGPGPPELDSEQP---------SRLFGQEELDPDSLS 748
L ++ SPA GP +++GP ++ +E+P S E P +++
Sbjct: 494 SLGNILQAKPTSSPAKGP--PQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMT 551
Query: 749 DASGSDGGRGPEPGVEPQDSRRRSPQEGPTWSRGRRSPRAPGEPT--------------- 793
A + P+ P+ + + + G ++PR G T
Sbjct: 552 AAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQR 611
Query: 794 PASFFIGDQNGDAVLSRKPLA-----APGDGEGLGQTAQPSPPARDGVYVSANGRMVIQL 848
PA + D+ + LA A G+GL Q S P + + G+ +
Sbjct: 612 PAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGL-QVKAASVPVKGSL-----GQGTAPV 665
Query: 849 RPGRSPEPDGPAPAFLRQES-FTKEPASGPPAPGKPPHISSHPLLQDLAATRAARMDFHS 907
PG++ A +++S ++E + A P + + A AA +
Sbjct: 666 LPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSA 725
Query: 908 QDTHLILKETETALAALEARLLSNSVDAECEGGSTPRPPEDALSGDSDVDTASTVSLRSG 967
+ T + ++++ + A+ S +PP STV R
Sbjct: 726 KGT-----------ISAPGKVVTAAAQAKQRSPSKVKPPVRNPQN-------STVLARGP 767
Query: 968 KSGPSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAREQSSERQHHPLGPT-DMGRGEPV 1026
S PS AQ + P +D G S E SE + L G+ +
Sbjct: 768 ASVPSVGKAVATAAQAQTGPE----EDSGS----SEEESDSEEEAETLAQVKPSGKTHQI 819
Query: 1027 RRSAIRRGHRPR-GSLDWPSEERGPVLAHLPSSDVMASNHETPEATGAGRLGSRRKPAAP 1085
R + PR G+ P + GP A D S+ E ++ G
Sbjct: 820 RAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIK 879
Query: 1086 PPSPAAREEQSRSSASSQKGPQALTRSNSLSTPRPTRASR-LRRARLGDASDTEAADGER 1144
P P + +RS A P ++ + STPR RAS R+ ++ D +
Sbjct: 880 P--PLIFVDPNRSPAGPAATP---AQAQAASTPRKARASESTARSSSSESEDEDVI---- 930
Query: 1145 GSLGNPEPVGRPAAEQAKKLSRLDILAMPRKR-----AGSFTGTSDPEAAPARTSFSGRS 1199
PA + R +++ MP S G S + + + +
Sbjct: 931 -----------PATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQE 979
Query: 1200 VELCCASRKP------TMAEARAVSRKAANTATTTGPRQPFSRARS--GSARYTS--TTQ 1249
S+K T A + +++KA+ QP S S G+ TS +T
Sbjct: 980 GPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTS 1039
Query: 1250 TPRAGSSSRARSRAP-------GPRDTDDDEEEPDPYGFIVQTAEIAEIARLSQTLV--- 1299
G++ + + P P +DD E+ D + E + A+ + TLV
Sbjct: 1040 VQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPT 1099
Query: 1300 -KDVAILAQEIHDVAGDGDTLGSSE------------PAHSASLSNMP---STP--ASTI 1341
L +E + + D + S+ PA+S + P S+P +ST+
Sbjct: 1100 PSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTL 1159
Query: 1342 SAREE 1346
+A+++
Sbjct: 1160 AAKDD 1164
>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b [Homo
sapiens]
Length = 1411
Score = 65.1 bits (157), Expect = 5e-10
Identities = 128/546 (23%), Positives = 189/546 (34%), Gaps = 130/546 (23%)
Query: 815 APGDGEGLGQTAQPSPPARDGVYVSANGRMVIQLRPGRSPEPDGPAPAFLRQESFTKEPA 874
A + E G+T P A G+ V L G+SP A S T+E
Sbjct: 125 AKAETEKAGKTGNSMPHP-------ATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEG 177
Query: 875 SGPP--APGKPPHISSHPLLQDLAATRAARMDFHSQDTHLILKETETALAALEARLLSNS 932
S P A KP +S A + D S+DT ET+ + A E L +
Sbjct: 178 SVPAFGAAAKPGMVS------------AGQADSSSEDTSSSSDETDVEVKASEKILQVRA 225
Query: 933 VDAECEG----GSTPRPPEDA---------------------LSGDSDVDTASTVSL--- 964
A +G G+TP PP A S DS+ +T + +L
Sbjct: 226 ASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQA 285
Query: 965 -RSGKSGP--SPTTPQPLRAQKEMSPSPPAAQDPGGTAL---------VSAREQSSERQH 1012
SGK+ + + P +K +P+PP P S+ E+S +
Sbjct: 286 KASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEE 345
Query: 1013 HPLGPTDMGRGEPVRRSAIRRGHRPR-GSLDWPSEERGPVLAHL----PSSDVMASNHET 1067
P G+ VR ++ PR G+ P + GP A + D +S+ E+
Sbjct: 346 APAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEES 405
Query: 1068 -------------------------PEAT-GAGRLGSRRKPAAP----PPSPAAR----E 1093
P +T G G LG P P P +P+A+ E
Sbjct: 406 DSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWE 465
Query: 1094 EQSRSSASSQKGPQALTRSNSLSTPRPTRASRLRRARLGDASDTEAADGERGSLGNPEPV 1153
E S SS+ S+S PT + + LG+ +A + G P+
Sbjct: 466 EDSESSSEES--------SDSSDGEVPTAVAPAQEKSLGNI--LQAKPTSSPAKGPPQKA 515
Query: 1154 GRPAAEQAKKLSRLDILAMPRKRAGSFTGTSDPEAAPARTSFSGRSVELCCASRKPTM-- 1211
G P A Q K +D + + S +D E APA + A KP +
Sbjct: 516 G-PVAVQVKAEKPMDNSESSEESSDS----ADSEEAPA---------AMTAAQAKPALKI 561
Query: 1212 AEARAVSRKAANTATTTGPRQPFSRARSGSARYTSTTQTPRAGSSSRARSRAPGPRDTDD 1271
+ +A +K T TT + R + + R T +P AGSS P +
Sbjct: 562 PQTKACPKK---TNTTASAKVAPVRVGTQAPRKAGTATSP-AGSSPAVAGGTQRPAEDSS 617
Query: 1272 DEEEPD 1277
EE D
Sbjct: 618 SSEESD 623
Score = 62.0 bits (149), Expect = 4e-09
Identities = 175/876 (19%), Positives = 293/876 (33%), Gaps = 125/876 (14%)
Query: 353 KHEDGTQSDSEDPLAKAASAAGVPLEASGEQVRL-QRQIKRDPQELLHNQQAFVIEFFDE 411
K E+ +QS SE+ ++ + A QVR K P++
Sbjct: 328 KREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGA------------A 375
Query: 412 DTPRKKRSQSFTHSPSGDPKADKRRGPTPADRDRPSVPA----PVQAGGRSSGPQRAGSL 467
P +K + G + D R +D DR ++ A V+ G+S + A ++
Sbjct: 376 PAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTM 435
Query: 468 KREKTEERLGSPSPASRTPARPFGSVGRRSRLAQDFMAQCLRESS----PAARPSPEKV- 522
+ G P PA P VG+ ++ + S A P+ EK
Sbjct: 436 GMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSL 495
Query: 523 -------PPVLPAPLTPHGTSPVGPPTPPPAPTDPQLTKARKQEEDDSLSDAGTYTI--- 572
P PA P PV P D + + DS T
Sbjct: 496 GNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQA 555
Query: 573 -------ETEA--QDTEVEEARKMIDQVFGVLESPELSRASS----------ATFRPVIR 613
+T+A + T + K+ G + A+S T RP
Sbjct: 556 KPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAED 615
Query: 614 GDRDESDDGGVAQRMALLQEFASRPLGAAPQAEHQGLPVPGSPG--------GQKWVSRW 665
E D + + ++ +G Q + +PV GS G G+ +
Sbjct: 616 SSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVT 675
Query: 666 ASLADSYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERADSPAGPESSRR--SGP 723
A+ D +E+ E + P +++ + + ++ + A S++ S P
Sbjct: 676 QVKAEKQEDSESSEE---ESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAP 732
Query: 724 GPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPE--PGVEPQDSRRRSPQEGPTWSR 781
G + Q + ++ P + + + RGP P V + Q GP
Sbjct: 733 GKVVTAAAQAKQR-SPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDS 791
Query: 782 GRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSAN 841
G + E + +G R LA + G A P+PP + G +
Sbjct: 792 GSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKG--AAPTPPGKTGPSAAQA 849
Query: 842 GRMVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSHPLLQDLAAT-RA 900
G+ + DG APA + K P P ++ P A+T R
Sbjct: 850 GKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRK 909
Query: 901 ARMDFHSQDTHLILKETETALAALEARLLSNSVDAECEGGSTPR-PPEDALSGDSDVDTA 959
AR + + E E + A + + + PR P+ +++G S +
Sbjct: 910 ARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKES 969
Query: 960 STVSLRSGKSGPSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAREQSSERQHHPLGPTD 1019
S +S GK P T ++S PA+ AL +++SE Q
Sbjct: 970 SRIS--DGKKQEGPAT--------QVSKKNPASLPLTQAALKVLAQKASEAQ-------- 1011
Query: 1020 MGRGEPVRRSAIRRGHRPRGSLDWPSEERGPVLAHLPSSDVMASNHETPEATGAGRLGSR 1079
PV R+ PS + LP++ ++ + +A G +L
Sbjct: 1012 ----PPVARTQ-------------PSSGVDSAVGTLPATSPQST---SVQAKGTNKL--- 1048
Query: 1080 RKPAAP--------PPSPAAREEQSRSSASSQ---KGPQALTRSNSLSTPRPTRASRLRR 1128
RKP P P S E+ S SS+ S+ +GPQ +++L P P+R L
Sbjct: 1049 RKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLG-PTPSRTETLVE 1107
Query: 1129 ARLGDASDTEAADGERGSL-GNPEPVGRPAAEQAKK 1163
++S+ + + L G P PA QA K
Sbjct: 1108 ETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASK 1143
Score = 58.5 bits (140), Expect = 5e-08
Identities = 211/1025 (20%), Positives = 352/1025 (34%), Gaps = 222/1025 (21%)
Query: 410 DEDTPRKKR--------SQSFTHSPSGDPKADKRRG--PTPADRDRPSVPAPVQAGGRSS 459
+E+TP K S + S K R+G P P + P+V A QAG R
Sbjct: 273 EEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAV-AKAQAGKREE 331
Query: 460 GPQRAGSLKREKTEERLGSPSPASRTPARPFGSVGRRSRLAQDFMAQCLRESSPAARPSP 519
Q + S + + EE P+ + P +R +S A+ SP
Sbjct: 332 DSQ-SSSEESDSEEEAPAQAKPSGKAPQ--------------------VRAASAPAKESP 370
Query: 520 EKVPPVLPAPLTPHGTSPVGPPTPPPAPTDPQLTKARKQEEDDSLSDAGTYTIETEAQDT 579
K G +P P PA Q+ KQEED S +E D+
Sbjct: 371 RK------------GAAPAPPRKTGPAAAQVQV---GKQEEDSRSS--------SEESDS 407
Query: 580 EVEEARKM-IDQVFGVLESPELSRASSATFRPVIRGDRDESDDGGVAQRMALLQEFASRP 638
+ E M QV + +SP++ AS+ P+ +G
Sbjct: 408 DREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKG------------------------ 443
Query: 639 LGAAPQAEHQGLPVPGSPGGQKWVSRWASLADSYSDPGLTEDGLGRRGGEPEGSLPVRMR 698
G P G P +P Q V +W ++S S+ E G P P + +
Sbjct: 444 AGPVP----PGKVGPATPSAQ--VGKWEEDSESSSE----ESSDSSDGEVPTAVAPAQEK 493
Query: 699 RRLPQLPSERADSPA-GPESSRRSGPGPPELDSEQP---------SRLFGQEELDPDSLS 748
L ++ SPA GP +++GP ++ +E+P S E P +++
Sbjct: 494 SLGNILQAKPTSSPAKGP--PQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMT 551
Query: 749 DASGSDGGRGPEPGVEPQDSRRRSPQEGPTWSRGRRSPRAPGEPT--------------- 793
A + P+ P+ + + + G ++PR G T
Sbjct: 552 AAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQR 611
Query: 794 PASFFIGDQNGDAVLSRKPLA-----APGDGEGLGQTAQPSPPARDGVYVSANGRMVIQL 848
PA + D+ + LA A G+GL Q S P + + G+ +
Sbjct: 612 PAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGL-QVKAASVPVKGSL-----GQGTAPV 665
Query: 849 RPGRSPEPDGPAPAFLRQES-FTKEPASGPPAPGKPPHISSHPLLQDLAATRAARMDFHS 907
PG++ A +++S ++E + A P + + A AA +
Sbjct: 666 LPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSA 725
Query: 908 QDTHLILKETETALAALEARLLSNSVDAECEGGSTPRPPEDALSGDSDVDTASTVSLRSG 967
+ T + ++++ + A+ S +PP STV R
Sbjct: 726 KGT-----------ISAPGKVVTAAAQAKQRSPSKVKPPVRNPQN-------STVLARGP 767
Query: 968 KSGPSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAREQSSERQHHPLGPT-DMGRGEPV 1026
S PS AQ + P +D G S E SE + L G+ +
Sbjct: 768 ASVPSVGKAVATAAQAQTGPE----EDSGS----SEEESDSEEEAETLAQVKPSGKTHQI 819
Query: 1027 RRSAIRRGHRPR-GSLDWPSEERGPVLAHLPSSDVMASNHETPEATGAGRLGSRRKPAAP 1085
R + PR G+ P + GP A D S+ E ++ G
Sbjct: 820 RAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIK 879
Query: 1086 PPSPAAREEQSRSSASSQKGPQALTRSNSLSTPRPTRASR-LRRARLGDASDTEAADGER 1144
P P + +RS A P ++ + STPR RAS R+ ++ D +
Sbjct: 880 P--PLIFVDPNRSPAGPAATP---AQAQAASTPRKARASESTARSSSSESEDEDVI---- 930
Query: 1145 GSLGNPEPVGRPAAEQAKKLSRLDILAMPRKR-----AGSFTGTSDPEAAPARTSFSGRS 1199
PA + R +++ MP S G S + + + +
Sbjct: 931 -----------PATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQE 979
Query: 1200 VELCCASRKP------TMAEARAVSRKAANTATTTGPRQPFSRARS--GSARYTS--TTQ 1249
S+K T A + +++KA+ QP S S G+ TS +T
Sbjct: 980 GPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTS 1039
Query: 1250 TPRAGSSSRARSRAP-------GPRDTDDDEEEPDPYGFIVQTAEIAEIAR--------- 1293
G++ + + P P +DD E+ D + E + A+
Sbjct: 1040 VQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTP 1099
Query: 1294 -LSQTLVKDVAILAQEIHDVAGDGDTLGSS------EPAHSASLSNMP---STP--ASTI 1341
++TLV++ A + E DV +L S PA+S + P S+P +ST+
Sbjct: 1100 SRTETLVEETAAESSE-DDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTL 1158
Query: 1342 SAREE 1346
+A+++
Sbjct: 1159 AAKDD 1163
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 63.2 bits (152), Expect = 2e-09
Identities = 243/1198 (20%), Positives = 407/1198 (33%), Gaps = 237/1198 (19%)
Query: 229 PTKETPQPSQPPE---VPAHEMPTKDAEAGGGGAAPVVQSHASFTIEFDDCSPGKMKIKD 285
P+ T S+ E VPA K G A + +S + E D GK +K
Sbjct: 163 PSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETD--VEGKPSVKP 220
Query: 286 -HITKFSLRQRRPPGKEATPGEMVSAETKVADWLVQND----PSLLHRVGPGDDRHSTKS 340
+ S+ + P ++A P A KV D Q P P ++ S++
Sbjct: 221 AQVKASSVSTKESPARKAAP-----APGKVGDVTPQVKGGALPPAKRAKKPEEESESSEE 275
Query: 341 DLPVHTRTLKGHKHEDGTQSDSEDPLAKAASAAGVPLEAS-----GEQVRLQRQIKRDPQ 395
G + + A +A A G P + + G+ + Q K
Sbjct: 276 GSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKP 335
Query: 396 ELLHNQQAFVIEFFDEDTPRKKR--------SQSFTHSPSGDPKADKRRG--PTPADRDR 445
E + +E+TP K S + S K R+G P P +
Sbjct: 336 EEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTG 395
Query: 446 PSVPAPVQAGGRSSGPQRAGSLKREKTEERLGSPSPASRTPARPFGSVGRRSRLAQDFMA 505
P+V A QAG R Q + S + + EE P+ + P
Sbjct: 396 PAV-AKAQAGKREEDSQ-SSSEESDSEEEAPAQAKPSGKAPQ------------------ 435
Query: 506 QCLRESSPAARPSPEKVPPVLPAPLTPHGTSPVGPPTPPPAPTDPQLTKARKQEEDDSLS 565
+R +S A+ SP K G +P P PA Q+ KQEED S
Sbjct: 436 --VRAASAPAKESPRK------------GAAPAPPRKTGPAAAQVQV---GKQEEDSRSS 478
Query: 566 DAGTYTIETEAQDTEVEEARKM-IDQVFGVLESPELSRASSATFRPVIRGDRDESDDGGV 624
+E D++ E M QV + +SP++ AS+ P+ +G
Sbjct: 479 --------SEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKG---------- 520
Query: 625 AQRMALLQEFASRPLGAAPQAEHQGLPVPGSPGGQKWVSRWASLADSYSDPGLTEDGLGR 684
G P G P +P Q V +W ++S S+ E
Sbjct: 521 --------------AGPVP----PGKVGPATPSAQ--VGKWEEDSESSSE----ESSDSS 556
Query: 685 RGGEPEGSLPVRMRRRLPQLPSERADSPA-GPESSRRSGPGPPELDSEQP---------S 734
G P P + + L ++ SPA GP +++GP ++ +E+P S
Sbjct: 557 DGEVPTAVAPAQEKSLGNILQAKPTSSPAKGP--PQKAGPVAVQVKAEKPMDNSESSEES 614
Query: 735 RLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQEGPTWSRGRRSPRAPGEPT- 793
E P +++ A + P+ P+ + + + G ++PR G T
Sbjct: 615 SDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATS 674
Query: 794 --------------PASFFIGDQNGDAVLSRKPLA-----APGDGEGLGQTAQPSPPARD 834
PA + D+ + LA A G+GL Q S P +
Sbjct: 675 PAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGL-QVKAASVPVKG 733
Query: 835 GVYVSANGRMVIQLRPGRSPEPDGPAPAFLRQES-FTKEPASGPPAPGKPPHISSHPLLQ 893
+ G+ + PG++ A +++S ++E + A P + +
Sbjct: 734 SL-----GQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKT 788
Query: 894 DLAATRAARMDFHSQDTHLILKETETALAALEARLLSNSVDAECEGGSTPRPPEDALSGD 953
A AA ++ T + ++++ + A+ S +PP
Sbjct: 789 QAKANPAAARAPSAKGT-----------ISAPGKVVTAAAQAKQRSPSKVKPPVRNPQN- 836
Query: 954 SDVDTASTVSLRSGKSGPSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAREQSSERQHH 1013
STV R S PS AQ + P +D G S E SE +
Sbjct: 837 ------STVLARGPASVPSVGKAVATAAQAQTGPE----EDSGS----SEEESDSEEEAE 882
Query: 1014 PLGPT-DMGRGEPVRRSAIRRGHRPR-GSLDWPSEERGPVLAHLPSSDVMASNHETPEAT 1071
L G+ +R + PR G+ P + GP A D S+ E ++
Sbjct: 883 TLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSD 942
Query: 1072 GAGRLGSRRKPAAPPPSPAAREEQSRSSASSQKGPQALTRSNSLSTPRPTRASR-LRRAR 1130
G P P + +RS A P ++ + STPR RAS R+
Sbjct: 943 GEAPAAVTSAQVIKP--PLIFVDPNRSPAGPAATP---AQAQAASTPRKARASESTARSS 997
Query: 1131 LGDASDTEAADGERGSLGNPEPVGRPAAEQAKKLSRLDILAMPRKRAGSFTGTSDPEAAP 1190
++ D + PA + R +++ MP T+ P AP
Sbjct: 998 SSESEDEDVI---------------PATQCLTPGIRTNVVTMP---------TAHPRIAP 1033
Query: 1191 ARTSFSGRSVELCCASRKPTMAEARAVSRKAANTATTTGPRQPFS-RARSGSARYTSTTQ 1249
+ S +G S + +++ + A + G S ++ S A+ T+ +
Sbjct: 1034 -KASMAGAS----SSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLR 1088
Query: 1250 TPRAGSSSRARSRAPGPRDTDDDEEEPDPYGFIVQTAEIAEIARLSQTLV----KDVAIL 1305
P+ +A P +DD E+ D + E + A+ + TLV L
Sbjct: 1089 KPKLPEVQQA---TKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETL 1145
Query: 1306 AQEIHDVAGDGDTLGSSE------------PAHSASLSNMP---STP--ASTISAREE 1346
+E + + D + S+ PA+S + P S+P +ST++A+++
Sbjct: 1146 VEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDD 1203
Score = 53.9 bits (128), Expect = 1e-06
Identities = 171/923 (18%), Positives = 296/923 (32%), Gaps = 102/923 (11%)
Query: 353 KHEDGTQSDSEDPLAKAASAAGVPLEASGEQVRL-QRQIKRDPQELLHNQQAFVIEFFDE 411
K E+ +QS SE+ ++ + A QVR K P++
Sbjct: 405 KREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGA------------A 452
Query: 412 DTPRKKRSQSFTHSPSGDPKADKRRGPTPADRDRPSVPA----PVQAGGRSSGPQRAGSL 467
P +K + G + D R +D DR ++ A V+ G+S + A ++
Sbjct: 453 PAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTM 512
Query: 468 KREKTEERLGSPSPASRTPARPFGSVGRRSRLAQDFMAQCLRESS----PAARPSPEKV- 522
+ G P PA P VG+ ++ + S A P+ EK
Sbjct: 513 GMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSL 572
Query: 523 -------PPVLPAPLTPHGTSPVGPPTPPPAPTDPQLTKARKQEEDDSLSDAGTYTI--- 572
P PA P PV P D + + DS T
Sbjct: 573 GNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQA 632
Query: 573 -------ETEA--QDTEVEEARKMIDQVFGVLESPELSRASS----------ATFRPVIR 613
+T+A + T + K+ G + A+S T RP
Sbjct: 633 KPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAED 692
Query: 614 GDRDESDDGGVAQRMALLQEFASRPLGAAPQAEHQGLPVPGSPG--------GQKWVSRW 665
E D + + ++ +G Q + +PV GS G G+ +
Sbjct: 693 SSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVT 752
Query: 666 ASLADSYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERADSPAGPESSRR--SGP 723
A+ D +E+ E + P +++ + + ++ + A S++ S P
Sbjct: 753 QVKAEKQEDSESSEE---ESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAP 809
Query: 724 GPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPE--PGVEPQDSRRRSPQEGPTWSR 781
G + Q + ++ P + + + RGP P V + Q GP
Sbjct: 810 GKVVTAAAQAKQR-SPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDS 868
Query: 782 GRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSAN 841
G + E + +G R LA + G A P+PP + G +
Sbjct: 869 GSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKG--AAPTPPGKTGPSAAQA 926
Query: 842 GRMVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSHPLLQDLAAT-RA 900
G+ + DG APA + K P P ++ P A+T R
Sbjct: 927 GKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRK 986
Query: 901 ARMDFHSQDTHLILKETETALAALEARLLSNSVDAECEGGSTPR-PPEDALSGDSDVDTA 959
AR + + E E + A + + + PR P+ +++G S +
Sbjct: 987 ARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKES 1046
Query: 960 STVSLRSGKSGPSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAR-EQSSERQHHPLGPT 1018
S +S + GP+ + SP + Q G L + + + P
Sbjct: 1047 SRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSD 1106
Query: 1019 DMGRGEPVRRSAIRRGHRPRG-----SLDWPSEERGPVL-----AHLPSSDVMA------ 1062
D + G P+G +L P+ R L A DV+A
Sbjct: 1107 DSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLL 1166
Query: 1063 SNHETPEATGAGRLGSRRKP-----------AAPPPSPAAREEQSRSSASSQKGPQALTR 1111
S + TP T A S+ P A P ++E A+ P+ +
Sbjct: 1167 SGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGK 1226
Query: 1112 SNSLSTPRPTRASRLRRARLGDASDTEAADGE--RGSLGNPEPVGRPAAEQAKKLSRLDI 1169
+ T P ++ + ++ + T A + LG P P+ + + ++
Sbjct: 1227 EAASGT-TPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTEL 1285
Query: 1170 LAMPRKRAGSFTGTSDPEAAPAR 1192
L RK+ T S + +R
Sbjct: 1286 LEQERKKVVDTTKESSRKGWESR 1308
Score = 53.5 bits (127), Expect = 2e-06
Identities = 156/714 (21%), Positives = 254/714 (35%), Gaps = 142/714 (19%)
Query: 658 GQK-WVSRWASLADSYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERADSPAGPE 716
GQK ++++ +L D Y+ T + LGR+ E + + R+ S S E
Sbjct: 35 GQKCFLAQPVTLLDIYTHWQQTSE-LGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEE 93
Query: 717 SSRRSGPGPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQEG 776
+ + P L S S L P S+ + + ++ + + G + P G
Sbjct: 94 AEAETAKATPRLASTNSSVLGADL---PSSMKEKAKAETEKAGKTG-----NSMPHPATG 145
Query: 777 PTWSR--GRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARD 834
T + +SPR EP+ + + + + + AA GQ S
Sbjct: 146 KTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTS- 204
Query: 835 GVYVSANGRMVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSHPLLQD 894
S++ ++ +P P A + +ES ++ A PAPGK ++ P ++
Sbjct: 205 ----SSSDETDVEGKPSVKPA-QVKASSVSTKESPARKAA---PAPGKVGDVT--PQVKG 254
Query: 895 LA---ATRAARMDFHSQDTHLILKETETALA-------ALEARLLSNSVDAECEG----G 940
A A RA + + S+ + + E A A A E L + A +G G
Sbjct: 255 GALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKG 314
Query: 941 STPRPPEDA---------------------LSGDSDVDTASTVSL----RSGKSGP--SP 973
+TP PP A S DS+ +T + +L SGK+ +
Sbjct: 315 ATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAA 374
Query: 974 TTPQPLRAQKEMSPSPPAAQDPGGTAL---------VSAREQSSERQHHPLGPTDMGRGE 1024
+ P +K +P+PP P S+ E+S + P G+
Sbjct: 375 SAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAP 434
Query: 1025 PVRRSAIRRGHRPR-GSLDWPSEERGPVLAHL----PSSDVMASNHET------------ 1067
VR ++ PR G+ P + GP A + D +S+ E+
Sbjct: 435 QVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNA 494
Query: 1068 -------------PEAT-GAGRLGSRRKPAAP----PPSPAAR----EEQSRSSASSQKG 1105
P +T G G LG P P P +P+A+ EE S SS+
Sbjct: 495 AQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEES-- 552
Query: 1106 PQALTRSNSLSTPRPTRASRLRRARLGDASDTEAADGERGSLGNPEPVGRPAAEQAKKLS 1165
S+S PT + + LG+ +A + G P+ G P A Q K
Sbjct: 553 ------SDSSDGEVPTAVAPAQEKSLGNI--LQAKPTSSPAKGPPQKAG-PVAVQVKAEK 603
Query: 1166 RLDILAMPRKRAGSFTGTSDPEAAPARTSFSGRSVELCCASRKPTM--AEARAVSRKAAN 1223
+D + + S +D E APA + A KP + + +A +K
Sbjct: 604 PMDNSESSEESSDS----ADSEEAPA---------AMTAAQAKPALKIPQTKACPKK--- 647
Query: 1224 TATTTGPRQPFSRARSGSARYTSTTQTPRAGSSSRARSRAPGPRDTDDDEEEPD 1277
T TT + R + + R T +P AGSS P + EE D
Sbjct: 648 TNTTASAKVAPVRVGTQAPRKAGTATSP-AGSSPAVAGGTQRPAEDSSSSEESD 700
>gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens]
Length = 2303
Score = 63.2 bits (152), Expect = 2e-09
Identities = 177/765 (23%), Positives = 253/765 (33%), Gaps = 164/765 (21%)
Query: 193 ERPKGPVQQDGELHGFRAPAEPQGCSFRREPSYFEIPTK------------ETPQPSQPP 240
ERP+G +++ APA P R +PS T P+PS+PP
Sbjct: 1540 ERPQG--RKEAPAPSKAAPAAPPPA--RTQPSLIADETPPCYSLSSSASSLSEPEPSEPP 1595
Query: 241 EV-PAHEMP--TKDAEAGGGGAAPVVQSHASFTIE--FDDCSP-------GKMKIKDHIT 288
V P P TKD GGG + A ++ P G + K T
Sbjct: 1596 AVHPRGREPAVTKDPGPGGGRDSSPSPRAAEELLQRCISSALPRRRPPVSGLRRRKPRAT 1655
Query: 289 KFSLRQR---RPPGKEATPGEMVS------------AETKVADWLVQNDPSLLHRVGPGD 333
+ R R G+EA + S + WL Q + D
Sbjct: 1656 RLDERPAEGSRERGEEAAGSDRASDLDSVEWRAIQEGANSIVTWLHQAAAATREASSESD 1715
Query: 334 DRHSTKSDLPVHTRTLKGHKHEDGTQSDSEDPLAKAASAAGVP-LEASGEQVRLQRQIKR 392
S S L V + TL+ KH G Q++ E A+ G ++ SG +
Sbjct: 1716 SILSFVSGLSVGS-TLQPPKHRKGRQAEGEMGSARRPEKRGAASVKTSGSP-----RSPA 1769
Query: 393 DPQELLHNQQAFVIEFFDEDTPRKKRSQSFTHSPSGDPKADKRRGPTPADRDR------- 445
P++ Q+ P R ++ + PS P+A + P P R
Sbjct: 1770 GPEKPRGTQKT------TPGVPAVLRGRTVIYVPSPAPRAQPKGTPGPRATPRKVAPPCL 1823
Query: 446 --PSVPAPVQAGGRSSGPQRAGSLKREKTEERLGSPSPASRTPARPFGSVGRRSRLAQDF 503
P+ PA V S G QR+ SL R L + S R+ P +RLA+
Sbjct: 1824 AQPAAPAKVP----SPGQQRSRSLHRPAKTSELATLSQPPRSATPP-------ARLAKT- 1871
Query: 504 MAQCLRESSPAARPSPEKVPPVL------------PAPLTPHGT----------SPV--- 538
+ ++SPA++P P K PPV P P TP T SPV
Sbjct: 1872 PSSSSSQTSPASQPLPRKRPPVTQAAGALPGPGASPVPKTPARTLLAKQHKTQRSPVRIP 1931
Query: 539 --------GPP-----TPPPAPTDPQLTKARKQEEDDSLSDAGTYTIETE-AQDTEVEEA 584
GPP P P P T+A L G + + + +E +
Sbjct: 1932 FMQRPARRGPPPLARAVPEPGPRGRAGTEAGPGARGGRL---GLVRVASALSSGSESSDR 1988
Query: 585 RKMIDQVFGVLESP-------ELSRASSATFRPVIRGDRDESDDGGVAQRMALLQEFASR 637
Q+ + ESP ELS A SA P R G A L
Sbjct: 1989 SGFRRQLTFIKESPGLRRRRSELSSAESAASAPQGASPR----RGRPALPAVFLCSSRCE 2044
Query: 638 PLGAAPQ----AEHQGLPVPGSPGGQKWVSRWASLADS---YSDPGLTEDGLGRRGGEPE 690
L AAP+ Q P G++ R S + S P + + R P
Sbjct: 2045 ELRAAPRQGPAPARQRPPAARPSPGERPARRTTSESPSRLPVRAPAARPETVKRYASLPH 2104
Query: 691 GSLPVRMRRRLPQLPSERADSPAGPESSRRSGPGPPE---------------LDSEQPSR 735
S+ R +P +PA +++RRS G P D + P
Sbjct: 2105 ISVARRPDGAVPA-------APASADAARRSSDGEPRPLPRVAAPGTTWRRIRDEDVPHI 2157
Query: 736 LFGQEELDPDSLSDASGSDGGRGPEP----GVEPQDSRRRSPQEGPTWSRGRRSPRAPGE 791
L L ++ D GP P Q +P+ + S + PG
Sbjct: 2158 LRSTLPATALPLRGSTPEDAPAGPPPRKTSDAVVQTEEVAAPKTNSSTSPSLETREPPGA 2217
Query: 792 PTPASF-FIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDG 835
P +G L++ P++AP EGLG P +R G
Sbjct: 2218 PAGGQLSLLGSDVDGPSLAKAPISAPFVHEGLGVAVGGFPASRHG 2262
Score = 51.2 bits (121), Expect = 8e-06
Identities = 199/874 (22%), Positives = 289/874 (33%), Gaps = 167/874 (19%)
Query: 451 PVQAGGRS-SGPQRAGSLKREKTEERLGSPSPASRTPARPFGSVGRRSRLAQDFMAQCLR 509
P + GG +G AG +RE+ P+P T +RP G+ + L + +CL
Sbjct: 1302 PERGGGAGGAGLHFAGHRRREE------GPAP---TGSRPRGAADQELEL----LRECLG 1348
Query: 510 ESSPAA--RPSPEKVPPVLPAPLTPHGTSPVGPPTPPPAPTDPQLTKARKQEEDDSLSDA 567
+ PA + + VP P+ PV P PAP +EDDS +D+
Sbjct: 1349 AAVPARLRKVASALVPGRRALPV------PVYMLVPAPAPA----------QEDDSCTDS 1392
Query: 568 GTYTIETEAQDTEVEEARKMIDQVFGVLESPELSRASSATFRPVIRGDRDESDDGGVAQR 627
E A + D+ L+ P RD+ GG A R
Sbjct: 1393 A------EGTPVNFSSAASLSDET---LQGPP----------------RDQP--GGPAGR 1425
Query: 628 MALLQEFASRPLGAAPQAEHQGLPVPGSPGGQKWVSRWASLADSYSDPGLTEDGLGRRGG 687
Q RP A H+ G G SR A + GL E LGR
Sbjct: 1426 ----QRPTGRPTSARQAMGHRHKA--GGAGRSAEQSRGAGK----NRAGL-ELPLGRPPS 1474
Query: 688 EP---EGSLPVRMRR--RLPQL----PSERA-------DSPAGPESSRRSGPGPPELDSE 731
P +GS P R R L L P+E A DS P ++ P P +
Sbjct: 1475 APADKDGSKPGRTRGDGALQSLCLTTPTEEAVYCFYGNDSDEEPPAA---APTPTHRRTS 1531
Query: 732 QPSRLFGQEELDPDSLSDASGSDGGRGPEPG-VEPQDSRRRSPQEGPTWSRGRRSPRAPG 790
R F +E + A P P +P +P P +S S +
Sbjct: 1532 AIPRAFTRERPQGRKEAPAPSKAAPAAPPPARTQPSLIADETP---PCYSLSS-SASSLS 1587
Query: 791 EPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSANGRMVIQLRP 850
EP P+ G R+P G G G+ + PSP A + + R + P
Sbjct: 1588 EPEPSEPPAVHPRG-----REPAVTKDPGPGGGRDSSPSPRAAEELLQ----RCISSALP 1638
Query: 851 GRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSHPLLQDLAATRAARMDFHSQDT 910
R P G R + PA G G+ S D RA + +S T
Sbjct: 1639 RRRPPVSGLRRRKPRATRLDERPAEGSRERGEEAAGSDRASDLDSVEWRAIQEGANSIVT 1698
Query: 911 HLILKETETALAALEARLLSNSVDAECEG---GSTPRPPEDALSGDSDVDTAST------ 961
L + A A EA S+S+ + G GST +PP+ ++ + S
Sbjct: 1699 WL----HQAAAATREASSESDSILSFVSGLSVGSTLQPPKHRKGRQAEGEMGSARRPEKR 1754
Query: 962 --VSLRSGKSGPSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAREQSSERQHHPLGPTD 1019
S+++ S SP P+ R ++ +P PA V + P
Sbjct: 1755 GAASVKTSGSPRSPAGPEKPRGTQKTTPGVPAVLRGRTVIYVPSP-----------APRA 1803
Query: 1020 MGRGEPVRRSAIRRGHRPRGSLDWPSEERGPVLAHLPSSDVMASNHETPEATGAGRLGSR 1079
+G P R+ R+ P ++ P P S H + + L
Sbjct: 1804 QPKGTPGPRATPRKVAPP-----CLAQPAAPAKVPSPGQQRSRSLHRPAKTSELATLSQP 1858
Query: 1080 RKPAAPPPSPAAREEQSRSSASSQKGPQ----------------ALTRSNSLSTPRPTRA 1123
+ A PP AR ++ SS+SSQ P AL + P+
Sbjct: 1859 PRSATPP----ARLAKTPSSSSSQTSPASQPLPRKRPPVTQAAGALPGPGASPVPKTPAR 1914
Query: 1124 SRLRRARLGDASDTEAADGERGSLGNPEPVGRPAAEQAKKLSRLDILAMPRKRAGSFTGT 1183
+ L + S +R + P P+ R E + R A P R G
Sbjct: 1915 TLLAKQHKTQRSPVRIPFMQRPARRGPPPLARAVPEPGPR-GRAGTEAGPGARGGRLGLV 1973
Query: 1184 SDPEAAPARTSFSGRS---VELCCASRKPTMAEARAVSRKAANTATTTGPRQPFSRARSG 1240
A + + S RS +L P + R+ A + A+ P R R
Sbjct: 1974 RVASALSSGSESSDRSGFRRQLTFIKESPGLRRRRSELSSAESAASAPQGASP-RRGRPA 2032
Query: 1241 -------SARYTSTTQTPRAGSSSRARSRAPGPR 1267
S+R PR G + AR R P R
Sbjct: 2033 LPAVFLCSSRCEELRAAPRQGPAP-ARQRPPAAR 2065
Score = 50.1 bits (118), Expect = 2e-05
Identities = 164/801 (20%), Positives = 257/801 (32%), Gaps = 106/801 (13%)
Query: 444 DRPSVPAPVQAGGRSSGPQRAGSLKREKTEERLGSPSPASRTPARPFGSVGRRSRLAQDF 503
+ P AP R+S RA RE+ + R +P+P+ PA P + + S +A +
Sbjct: 1516 EEPPAAAPTPTHRRTSAIPRA--FTRERPQGRKEAPAPSKAAPAAPPPARTQPSLIADET 1573
Query: 504 MAQCLRESSPAARPSPEKVPPVLPAPLTPHGTSPVGPPTPPPAPTDPQLTKARKQEEDDS 563
SS ++ PE P P + P G P T P P + + + ++
Sbjct: 1574 PPCYSLSSSASSLSEPE---PSEPPAVHPRGREPA--VTKDPGPGGGRDSSPSPRAAEEL 1628
Query: 564 LSDAGTYTIETEAQDTEVEEARKMIDQVFGVLESPELSRASSATFRPVIRGDRDESDDGG 623
L + + RK RA+ RP G R+ ++
Sbjct: 1629 LQRCISSALPRRRPPVSGLRRRK--------------PRATRLDERPA-EGSRERGEEAA 1673
Query: 624 VAQRMALLQEFASRPLGAAPQA----EHQGLPVPGSPGGQKWVSRWASLADSYSDPGLTE 679
+ R + L R + + HQ + S S +
Sbjct: 1674 GSDRASDLDSVEWRAIQEGANSIVTWLHQAAAATREASSES--DSILSFVSGLSVGSTLQ 1731
Query: 680 DGLGRRGGEPEGSLPVRMRRRLPQLPSERAD----SPAGPESSRRSGPGPPELDSEQPSR 735
R+G + EG + R S + SPAGPE R + P + P+
Sbjct: 1732 PPKHRKGRQAEGEMGSARRPEKRGAASVKTSGSPRSPAGPEKPRGTQKTTPGV----PAV 1787
Query: 736 LFGQEEL---DPDSLSDASGSDGGRGPEPGVEP-----QDSRRRSPQEGPTWSRGRRSPR 787
L G+ + P + G+ G R V P + + P G SR P
Sbjct: 1788 LRGRTVIYVPSPAPRAQPKGTPGPRATPRKVAPPCLAQPAAPAKVPSPGQQRSRSLHRPA 1847
Query: 788 APGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSANGRMVIQ 847
E S A L++ P ++ +QP P R V +A
Sbjct: 1848 KTSELATLSQPPRSATPPARLAKTPSSSSSQ---TSPASQPLPRKRPPVTQAAGALP--- 1901
Query: 848 LRPGRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSHPLLQDLAATRAARMDFHS 907
PG SP P PA L ++ T+ P +P PL + +
Sbjct: 1902 -GPGASPVPKTPARTLLAKQHKTQRSPVRIPFMQRPARRGPPPLARAVPEPGPRGR---- 1956
Query: 908 QDTHLILKETETALAALEARLLSNSVDAECEGGSTPRPPEDALSGDSDVDTASTVSLRSG 967
TE A RL V + GS S D ++
Sbjct: 1957 -------AGTEAGPGARGGRLGLVRVASALSSGSE--------SSDRSGFRRQLTFIKE- 2000
Query: 968 KSGPSPTTPQPLRAQKEMSPSPPAAQDPGGT----------ALVSAREQSSERQHHP-LG 1016
+P R + E+S + AA P G A+ + E + P G
Sbjct: 2001 -------SPGLRRRRSELSSAESAASAPQGASPRRGRPALPAVFLCSSRCEELRAAPRQG 2053
Query: 1017 PTDMGRGEPVRRSAIRRGHRPRGSLDWPSEERGPVLAHLPSSDVMASNHETPEATGAGRL 1076
P + P R + G RP S R PV A + + P + A
Sbjct: 2054 PAPARQRPPAARPS--PGERPARRTTSESPSRLPVRAPAARPETVKRYASLPHISVA--- 2108
Query: 1077 GSRRKPAAPPPSPAAREEQSRSSASSQKG-PQALTRSNSLSTPRPTRASRLRRARLGDAS 1135
RR A P +PA+ + RSS + P+ + R + R+ L
Sbjct: 2109 --RRPDGAVPAAPASADAARRSSDGEPRPLPRVAAPGTTWRRIRDEDVPHILRSTL---- 2162
Query: 1136 DTEAADGERGSLGNPEPVGRPAAEQAKKLSRLDILAMPRKRAGSFTG--TSDPEAAPA-- 1191
A RGS P G P + + + + + +A P+ + + T +P APA
Sbjct: 2163 -PATALPLRGSTPEDAPAGPPPRKTSDAVVQTEEVAAPKTNSSTSPSLETREPPGAPAGG 2221
Query: 1192 RTSFSGRSVELCCASRKPTMA 1212
+ S G V+ ++ P A
Sbjct: 2222 QLSLLGSDVDGPSLAKAPISA 2242
Score = 35.8 bits (81), Expect = 0.33
Identities = 79/333 (23%), Positives = 131/333 (39%), Gaps = 60/333 (18%)
Query: 963 SLRSGKSGPSPTTPQPLRAQKEM---SPSPPAAQDPGGTALVSAREQSSERQHHPL--GP 1017
+L S + P P+P R ++ PPA + A V + S QH PL G
Sbjct: 949 ALASRREDPRCGQPRPSRLDLDLPGCQAEPPAREATSADARVRTIKLSPTYQHVPLLEGA 1008
Query: 1018 TDMGRGEPVRRSAIRRGHRPRGSLDWPSEERGPVLAHLPSSDVMASNHETPEATGAGRLG 1077
+ G EP+ I G R + A LP+ + + PE
Sbjct: 1009 SRAG-AEPLAGPGISPGARKQ--------------AWLPADHLS----KVPE-------- 1041
Query: 1078 SRRKPAAPPPSPAAREEQSRSSASSQKGPQALTRSNSLSTPRPTRASRLRRARLGDASDT 1137
K AA P S A++ Q ++Q+GP +L+R +SLS+ + A R + GD D+
Sbjct: 1042 ---KLAAAPLSVASKALQK---LAAQEGPLSLSRCSSLSS--LSSAGRPGPSEGGDLDDS 1093
Query: 1138 EAADGERGSLGNPEPVGRPAAE-----QAKKLSRLDI-LAMPRKRAGSFTGTSDPEAAPA 1191
++ SL E G AE +A + L + + PR+ G G D A P+
Sbjct: 1094 DS------SLEGLEEAGPSEAELDSTWRAPGATSLPVAIPAPRRNRGRGLGVED--ATPS 1145
Query: 1192 RTSFSGRSVELCCASRKPTMAEARAVSRKAANTATTTGPRQPFSRARSGSARYTSTTQTP 1251
+S + SR + ++ + + ++ P +P S SG+ S ++ P
Sbjct: 1146 SSSENYVQETPLVLSR---CSSVSSLGSFESPSIASSIPSEPCSGQGSGT---ISPSELP 1199
Query: 1252 RAGSSSRARSRAPGPRDTDDDEEEPDPYGFIVQ 1284
+ + SR+ P + P+ F +Q
Sbjct: 1200 DSPGQTMPPSRSKTPPLAPAPQGPPEATQFSLQ 1232
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 62.0 bits (149), Expect = 4e-09
Identities = 175/876 (19%), Positives = 293/876 (33%), Gaps = 125/876 (14%)
Query: 353 KHEDGTQSDSEDPLAKAASAAGVPLEASGEQVRL-QRQIKRDPQELLHNQQAFVIEFFDE 411
K E+ +QS SE+ ++ + A QVR K P++
Sbjct: 405 KREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGA------------A 452
Query: 412 DTPRKKRSQSFTHSPSGDPKADKRRGPTPADRDRPSVPA----PVQAGGRSSGPQRAGSL 467
P +K + G + D R +D DR ++ A V+ G+S + A ++
Sbjct: 453 PAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTM 512
Query: 468 KREKTEERLGSPSPASRTPARPFGSVGRRSRLAQDFMAQCLRESS----PAARPSPEKV- 522
+ G P PA P VG+ ++ + S A P+ EK
Sbjct: 513 GMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSL 572
Query: 523 -------PPVLPAPLTPHGTSPVGPPTPPPAPTDPQLTKARKQEEDDSLSDAGTYTI--- 572
P PA P PV P D + + DS T
Sbjct: 573 GNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQA 632
Query: 573 -------ETEA--QDTEVEEARKMIDQVFGVLESPELSRASS----------ATFRPVIR 613
+T+A + T + K+ G + A+S T RP
Sbjct: 633 KPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAED 692
Query: 614 GDRDESDDGGVAQRMALLQEFASRPLGAAPQAEHQGLPVPGSPG--------GQKWVSRW 665
E D + + ++ +G Q + +PV GS G G+ +
Sbjct: 693 SSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVT 752
Query: 666 ASLADSYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERADSPAGPESSRR--SGP 723
A+ D +E+ E + P +++ + + ++ + A S++ S P
Sbjct: 753 QVKAEKQEDSESSEE---ESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAP 809
Query: 724 GPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPE--PGVEPQDSRRRSPQEGPTWSR 781
G + Q + ++ P + + + RGP P V + Q GP
Sbjct: 810 GKVVTAAAQAKQR-SPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDS 868
Query: 782 GRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSAN 841
G + E + +G R LA + G A P+PP + G +
Sbjct: 869 GSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKG--AAPTPPGKTGPSAAQA 926
Query: 842 GRMVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSHPLLQDLAAT-RA 900
G+ + DG APA + K P P ++ P A+T R
Sbjct: 927 GKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRK 986
Query: 901 ARMDFHSQDTHLILKETETALAALEARLLSNSVDAECEGGSTPR-PPEDALSGDSDVDTA 959
AR + + E E + A + + + PR P+ +++G S +
Sbjct: 987 ARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKES 1046
Query: 960 STVSLRSGKSGPSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAREQSSERQHHPLGPTD 1019
S +S GK P T ++S PA+ AL +++SE Q
Sbjct: 1047 SRIS--DGKKQEGPAT--------QVSKKNPASLPLTQAALKVLAQKASEAQ-------- 1088
Query: 1020 MGRGEPVRRSAIRRGHRPRGSLDWPSEERGPVLAHLPSSDVMASNHETPEATGAGRLGSR 1079
PV R+ PS + LP++ ++ + +A G +L
Sbjct: 1089 ----PPVARTQ-------------PSSGVDSAVGTLPATSPQST---SVQAKGTNKL--- 1125
Query: 1080 RKPAAP--------PPSPAAREEQSRSSASSQ---KGPQALTRSNSLSTPRPTRASRLRR 1128
RKP P P S E+ S SS+ S+ +GPQ +++L P P+R L
Sbjct: 1126 RKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLG-PTPSRTETLVE 1184
Query: 1129 ARLGDASDTEAADGERGSL-GNPEPVGRPAAEQAKK 1163
++S+ + + L G P PA QA K
Sbjct: 1185 ETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASK 1220
Score = 61.2 bits (147), Expect = 7e-09
Identities = 249/1219 (20%), Positives = 413/1219 (33%), Gaps = 242/1219 (19%)
Query: 229 PTKETPQPSQPPE---VPAHEMPTKDAEAGGGGAAPVVQSHASFTIEFDDCSPGKMKIKD 285
P+ T S+ E VPA K G A + +S + E D GK +K
Sbjct: 163 PSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETD--VEGKPSVKP 220
Query: 286 -HITKFSLRQRRPPGKEATPGEMVSAETKVADWLVQND----PSLLHRVGPGDDRHSTKS 340
+ S+ + P ++A P A KV D Q P P ++ S++
Sbjct: 221 AQVKASSVSTKESPARKAAP-----APGKVGDVTPQVKGGALPPAKRAKKPEEESESSEE 275
Query: 341 DLPVHTRTLKGHKHEDGTQSDSEDPLAKAASAAGVPLEAS-----GEQVRLQRQIKRDPQ 395
G + + A +A A G P + + G+ + Q K
Sbjct: 276 GSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKP 335
Query: 396 ELLHNQQAFVIEFFDEDTPRKKR--------SQSFTHSPSGDPKADKRRG--PTPADRDR 445
E + +E+TP K S + S K R+G P P +
Sbjct: 336 EEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTG 395
Query: 446 PSVPAPVQAGGRSSGPQRAGSLKREKTEERLGSPSPASRTPARPFGSVGRRSRLAQDFMA 505
P+V A QAG R Q + S + + EE P+ + P
Sbjct: 396 PAV-AKAQAGKREEDSQ-SSSEESDSEEEAPAQAKPSGKAPQ------------------ 435
Query: 506 QCLRESSPAARPSPEKVPPVLPAPLTPHGTSPVGPPTPPPAPTDPQLTKARKQEEDDSLS 565
+R +S A+ SP K G +P P PA Q+ KQEED S
Sbjct: 436 --VRAASAPAKESPRK------------GAAPAPPRKTGPAAAQVQV---GKQEEDSRSS 478
Query: 566 DAGTYTIETEAQDTEVEEARKM-IDQVFGVLESPELSRASSATFRPVIRGDRDESDDGGV 624
+E D++ E M QV + +SP++ AS+ P+ +G
Sbjct: 479 --------SEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKG---------- 520
Query: 625 AQRMALLQEFASRPLGAAPQAEHQGLPVPGSPGGQKWVSRWASLADSYSDPGLTEDGLGR 684
G P G P +P Q V +W ++S S+ E
Sbjct: 521 --------------AGPVP----PGKVGPATPSAQ--VGKWEEDSESSSE----ESSDSS 556
Query: 685 RGGEPEGSLPVRMRRRLPQLPSERADSPA-GPESSRRSGPGPPELDSEQP---------S 734
G P P + + L ++ SPA GP +++GP ++ +E+P S
Sbjct: 557 DGEVPTAVAPAQEKSLGNILQAKPTSSPAKGP--PQKAGPVAVQVKAEKPMDNSESSEES 614
Query: 735 RLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQEGPTWSRGRRSPRAPGEPT- 793
E P +++ A + P+ P+ + + + G ++PR G T
Sbjct: 615 SDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATS 674
Query: 794 --------------PASFFIGDQNGDAVLSRKPLA-----APGDGEGLGQTAQPSPPARD 834
PA + D+ + LA A G+GL Q S P +
Sbjct: 675 PAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGL-QVKAASVPVKG 733
Query: 835 GVYVSANGRMVIQLRPGRSPEPDGPAPAFLRQES-FTKEPASGPPAPGKPPHISSHPLLQ 893
+ G+ + PG++ A +++S ++E + A P + +
Sbjct: 734 SL-----GQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKT 788
Query: 894 DLAATRAARMDFHSQDTHLILKETETALAALEARLLSNSVDAECEGGSTPRPPEDALSGD 953
A AA ++ T + ++++ + A+ S +PP
Sbjct: 789 QAKANPAAARAPSAKGT-----------ISAPGKVVTAAAQAKQRSPSKVKPPVRNPQN- 836
Query: 954 SDVDTASTVSLRSGKSGPSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAREQSSERQHH 1013
STV R S PS AQ + P +D G S E SE +
Sbjct: 837 ------STVLARGPASVPSVGKAVATAAQAQTGPE----EDSGS----SEEESDSEEEAE 882
Query: 1014 PLGPT-DMGRGEPVRRSAIRRGHRPR-GSLDWPSEERGPVLAHLPSSDVMASNHETPEAT 1071
L G+ +R + PR G+ P + GP A D S+ E ++
Sbjct: 883 TLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSD 942
Query: 1072 GAGRLGSRRKPAAPPPSPAAREEQSRSSASSQKGPQALTRSNSLSTPRPTRASR-LRRAR 1130
G P P + +RS A P ++ + STPR RAS R+
Sbjct: 943 GEAPAAVTSAQVIKP--PLIFVDPNRSPAGPAATP---AQAQAASTPRKARASESTARSS 997
Query: 1131 LGDASDTEAADGERGSLGNPEPVGRPAAEQAKKLSRLDILAMPRKR-----AGSFTGTSD 1185
++ D + PA + R +++ MP S G S
Sbjct: 998 SSESEDEDVI---------------PATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASS 1042
Query: 1186 PEAAPARTSFSGRSVELCCASRKP------TMAEARAVSRKAANTATTTGPRQPFSRARS 1239
+ + + + S+K T A + +++KA+ QP S S
Sbjct: 1043 SKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDS 1102
Query: 1240 --GSARYTS--TTQTPRAGSSSRARSRAP-------GPRDTDDDEEEPDPYGFIVQTAEI 1288
G+ TS +T G++ + + P P +DD E+ D + E
Sbjct: 1103 AVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEG 1162
Query: 1289 AEIAR----------LSQTLVKDVAILAQEIHDVAGDGDTLGSS------EPAHSASLSN 1332
+ A+ ++TLV++ A + E DV +L S PA+S +
Sbjct: 1163 PQGAKSAHTLGPTPSRTETLVEETAAESSE-DDVVAPSQSLLSGYMTPGLTPANSQASKA 1221
Query: 1333 MP---STP--ASTISAREE 1346
P S+P +ST++A+++
Sbjct: 1222 TPKLDSSPSVSSTLAAKDD 1240
Score = 53.5 bits (127), Expect = 2e-06
Identities = 156/714 (21%), Positives = 254/714 (35%), Gaps = 142/714 (19%)
Query: 658 GQK-WVSRWASLADSYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERADSPAGPE 716
GQK ++++ +L D Y+ T + LGR+ E + + R+ S S E
Sbjct: 35 GQKCFLAQPVTLLDIYTHWQQTSE-LGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEE 93
Query: 717 SSRRSGPGPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQEG 776
+ + P L S S L P S+ + + ++ + + G + P G
Sbjct: 94 AEAETAKATPRLASTNSSVLGADL---PSSMKEKAKAETEKAGKTG-----NSMPHPATG 145
Query: 777 PTWSR--GRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARD 834
T + +SPR EP+ + + + + + AA GQ S
Sbjct: 146 KTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTS- 204
Query: 835 GVYVSANGRMVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSHPLLQD 894
S++ ++ +P P A + +ES ++ A PAPGK ++ P ++
Sbjct: 205 ----SSSDETDVEGKPSVKPA-QVKASSVSTKESPARKAA---PAPGKVGDVT--PQVKG 254
Query: 895 LA---ATRAARMDFHSQDTHLILKETETALA-------ALEARLLSNSVDAECEG----G 940
A A RA + + S+ + + E A A A E L + A +G G
Sbjct: 255 GALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKG 314
Query: 941 STPRPPEDA---------------------LSGDSDVDTASTVSL----RSGKSGP--SP 973
+TP PP A S DS+ +T + +L SGK+ +
Sbjct: 315 ATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAA 374
Query: 974 TTPQPLRAQKEMSPSPPAAQDPGGTAL---------VSAREQSSERQHHPLGPTDMGRGE 1024
+ P +K +P+PP P S+ E+S + P G+
Sbjct: 375 SAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAP 434
Query: 1025 PVRRSAIRRGHRPR-GSLDWPSEERGPVLAHL----PSSDVMASNHET------------ 1067
VR ++ PR G+ P + GP A + D +S+ E+
Sbjct: 435 QVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNA 494
Query: 1068 -------------PEAT-GAGRLGSRRKPAAP----PPSPAAR----EEQSRSSASSQKG 1105
P +T G G LG P P P +P+A+ EE S SS+
Sbjct: 495 AQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEES-- 552
Query: 1106 PQALTRSNSLSTPRPTRASRLRRARLGDASDTEAADGERGSLGNPEPVGRPAAEQAKKLS 1165
S+S PT + + LG+ +A + G P+ G P A Q K
Sbjct: 553 ------SDSSDGEVPTAVAPAQEKSLGNI--LQAKPTSSPAKGPPQKAG-PVAVQVKAEK 603
Query: 1166 RLDILAMPRKRAGSFTGTSDPEAAPARTSFSGRSVELCCASRKPTM--AEARAVSRKAAN 1223
+D + + S +D E APA + A KP + + +A +K
Sbjct: 604 PMDNSESSEESSDS----ADSEEAPA---------AMTAAQAKPALKIPQTKACPKK--- 647
Query: 1224 TATTTGPRQPFSRARSGSARYTSTTQTPRAGSSSRARSRAPGPRDTDDDEEEPD 1277
T TT + R + + R T +P AGSS P + EE D
Sbjct: 648 TNTTASAKVAPVRVGTQAPRKAGTATSP-AGSSPAVAGGTQRPAEDSSSSEESD 700
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo
sapiens]
Length = 1450
Score = 62.0 bits (149), Expect = 4e-09
Identities = 245/1198 (20%), Positives = 409/1198 (34%), Gaps = 238/1198 (19%)
Query: 229 PTKETPQPSQPPE---VPAHEMPTKDAEAGGGGAAPVVQSHASFTIEFDDCSPGKMKIKD 285
P+ T S+ E VPA K G A + +S + E D GK +K
Sbjct: 163 PSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETD--VEGKPSVKP 220
Query: 286 -HITKFSLRQRRPPGKEATPGEMVSAETKVADWLVQND----PSLLHRVGPGDDRHSTKS 340
+ S+ + P ++A P A KV D Q P P ++ S++
Sbjct: 221 AQVKASSVSTKESPARKAAP-----APGKVGDVTPQVKGGALPPAKRAKKPEEESESSEE 275
Query: 341 DLPVHTRTLKGHKHEDGTQSDSEDPLAKAASAAGVPLEAS-----GEQVRLQRQIKRDPQ 395
G + + A +A A G P + + G+ + Q K
Sbjct: 276 GSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKP 335
Query: 396 ELLHNQQAFVIEFFDEDTPRKKR--------SQSFTHSPSGDPKADKRRG--PTPADRDR 445
E + +E+TP K S + S K R+G P P +
Sbjct: 336 EEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTG 395
Query: 446 PSVPAPVQAGGRSSGPQRAGSLKREKTEERLGSPSPASRTPARPFGSVGRRSRLAQDFMA 505
P+V A QAG R Q + S + + EE P+ + P
Sbjct: 396 PAV-AKAQAGKREEDSQ-SSSEESDSEEEAPAQAKPSGKAPQ------------------ 435
Query: 506 QCLRESSPAARPSPEKVPPVLPAPLTPHGTSPVGPPTPPPAPTDPQLTKARKQEEDDSLS 565
+R +S A+ SP K G +P P PA Q+ KQEED S
Sbjct: 436 --VRAASAPAKESPRK------------GAAPAPPRKTGPAAAQVQV---GKQEEDSRSS 478
Query: 566 DAGTYTIETEAQDTEVEEARKM-IDQVFGVLESPELSRASSATFRPVIRGDRDESDDGGV 624
+E D++ E M QV + +SP++ AS+ P+ +G
Sbjct: 479 --------SEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKG---------- 520
Query: 625 AQRMALLQEFASRPLGAAPQAEHQGLPVPGSPGGQKWVSRWASLADSYSDPGLTEDGLGR 684
G P G P +P Q V +W ++S S+ E
Sbjct: 521 --------------AGPVP----PGKVGPATPSAQ--VGKWEEDSESSSE----ESSDSS 556
Query: 685 RGGEPEGSLPVRMRRRLPQLPSERADSPA-GPESSRRSGPGPPELDSEQP---------S 734
G P P + + L ++ SPA GP +++GP ++ +E+P S
Sbjct: 557 DGEVPTAVAPAQEKSLGNILQAKPTSSPAKGP--PQKAGPVAVQVKAEKPMDNSESSEES 614
Query: 735 RLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQEGPTWSRGRRSPRAPGEPT- 793
E P +++ A + P+ P+ + + + G ++PR G T
Sbjct: 615 SDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATS 674
Query: 794 --------------PASFFIGDQNGDAVLSRKPLA-----APGDGEGLGQTAQPSPPARD 834
PA + D+ + LA A G+GL Q S P +
Sbjct: 675 PAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGL-QVKAASVPVKG 733
Query: 835 GVYVSANGRMVIQLRPGRSPEPDGPAPAFLRQES-FTKEPASGPPAPGKPPHISSHPLLQ 893
+ G+ + PG++ A +++S ++E + A P + +
Sbjct: 734 SL-----GQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKT 788
Query: 894 DLAATRAARMDFHSQDTHLILKETETALAALEARLLSNSVDAECEGGSTPRPPEDALSGD 953
A AA ++ T + ++++ + A+ S +PP
Sbjct: 789 QAKANPAAARAPSAKGT-----------ISAPGKVVTAAAQAKQRSPSKVKPPVRNPQN- 836
Query: 954 SDVDTASTVSLRSGKSGPSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAREQSSERQHH 1013
STV R S PS AQ + P +D G S E SE +
Sbjct: 837 ------STVLARGPASVPSVGKAVATAAQAQTGPE----EDSGS----SEEESDSEEEAE 882
Query: 1014 PLGPT-DMGRGEPVRRSAIRRGHRPR-GSLDWPSEERGPVLAHLPSSDVMASNHETPEAT 1071
L G+ +R + PR G+ P + GP A D S+ E ++
Sbjct: 883 TLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSD 942
Query: 1072 GAGRLGSRRKPAAPPPSPAAREEQSRSSASSQKGPQALTRSNSLSTPRPTRASR-LRRAR 1130
G P P + +RS A P ++ + STPR RAS R+
Sbjct: 943 GEAPAAVTSAQVIKP--PLIFVDPNRSPAGPAATP---AQAQAASTPRKARASESTARSS 997
Query: 1131 LGDASDTEAADGERGSLGNPEPVGRPAAEQAKKLSRLDILAMPRKRAGSFTGTSDPEAAP 1190
++ D + PA + R +++ MP T+ P AP
Sbjct: 998 SSESEDEDVI---------------PATQCLTPGIRTNVVTMP---------TAHPRIAP 1033
Query: 1191 ARTSFSGRSVELCCASRKPTMAEARAVSRKAANTATTTGPRQPFS-RARSGSARYTSTTQ 1249
+ S +G S + +++ + A + G S ++ S A+ T+ +
Sbjct: 1034 -KASMAGAS----SSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLR 1088
Query: 1250 TPRAGSSSRARSRAPGPRDTDDDEEEPDPYGFIVQTAEIAEIAR----------LSQTLV 1299
P+ +A P +DD E+ D + E + A+ ++TLV
Sbjct: 1089 KPKLPEVQQA---TKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLV 1145
Query: 1300 KDVAILAQEIHDVAGDGDTLGSS------EPAHSASLSNMP---STP--ASTISAREE 1346
++ A + E DV +L S PA+S + P S+P +ST++A+++
Sbjct: 1146 EETAAESSE-DDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDD 1202
Score = 55.8 bits (133), Expect = 3e-07
Identities = 175/928 (18%), Positives = 298/928 (32%), Gaps = 113/928 (12%)
Query: 353 KHEDGTQSDSEDPLAKAASAAGVPLEASGEQVRL-QRQIKRDPQELLHNQQAFVIEFFDE 411
K E+ +QS SE+ ++ + A QVR K P++
Sbjct: 405 KREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGA------------A 452
Query: 412 DTPRKKRSQSFTHSPSGDPKADKRRGPTPADRDRPSVPA----PVQAGGRSSGPQRAGSL 467
P +K + G + D R +D DR ++ A V+ G+S + A ++
Sbjct: 453 PAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTM 512
Query: 468 KREKTEERLGSPSPASRTPARPFGSVGRRSRLAQDFMAQCLRESS----PAARPSPEKV- 522
+ G P PA P VG+ ++ + S A P+ EK
Sbjct: 513 GMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSL 572
Query: 523 -------PPVLPAPLTPHGTSPVGPPTPPPAPTDPQLTKARKQEEDDSLSDAGTYTI--- 572
P PA P PV P D + + DS T
Sbjct: 573 GNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQA 632
Query: 573 -------ETEA--QDTEVEEARKMIDQVFGVLESPELSRASS----------ATFRPVIR 613
+T+A + T + K+ G + A+S T RP
Sbjct: 633 KPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAED 692
Query: 614 GDRDESDDGGVAQRMALLQEFASRPLGAAPQAEHQGLPVPGSPG--------GQKWVSRW 665
E D + + ++ +G Q + +PV GS G G+ +
Sbjct: 693 SSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVT 752
Query: 666 ASLADSYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERADSPAGPESSRR--SGP 723
A+ D +E+ E + P +++ + + ++ + A S++ S P
Sbjct: 753 QVKAEKQEDSESSEE---ESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAP 809
Query: 724 GPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPE--PGVEPQDSRRRSPQEGPTWSR 781
G + Q + ++ P + + + RGP P V + Q GP
Sbjct: 810 GKVVTAAAQAKQR-SPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDS 868
Query: 782 GRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSAN 841
G + E + +G R LA + G A P+PP + G +
Sbjct: 869 GSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKG--AAPTPPGKTGPSAAQA 926
Query: 842 GRMVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSHPLLQDLAAT-RA 900
G+ + DG APA + K P P ++ P A+T R
Sbjct: 927 GKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRK 986
Query: 901 ARMDFHSQDTHLILKETETALAALEARLLSNSVDAECEGGSTPR-PPEDALSGDSDVDTA 959
AR + + E E + A + + + PR P+ +++G S +
Sbjct: 987 ARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKES 1046
Query: 960 STVSLRSGKSGPS-----------PTTPQPLRAQ-----KEMSPSPPAAQDPGGTALVSA 1003
S +S + GP+ T+PQ Q K P P Q T +
Sbjct: 1047 SRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQ--ATKAPES 1104
Query: 1004 REQSSERQHHPLGPTDMGRGEPVRRSAIRRGHRPRGSLDWPSEERGPVLAHLPSSDVMA- 1062
+ S + G + G G +SA G P + E A DV+A
Sbjct: 1105 SDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEE----TAAESSEDDVVAP 1160
Query: 1063 -----SNHETPEATGAGRLGSRRKP-----------AAPPPSPAAREEQSRSSASSQKGP 1106
S + TP T A S+ P A P ++E A+ P
Sbjct: 1161 SQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSP 1220
Query: 1107 QALTRSNSLSTPRPTRASRLRRARLGDASDTEAADGE--RGSLGNPEPVGRPAAEQAKKL 1164
+ + + T P ++ + ++ + T A + LG P P+ + +
Sbjct: 1221 KTGGKEAASGT-TPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVK 1279
Query: 1165 SRLDILAMPRKRAGSFTGTSDPEAAPAR 1192
++L RK+ T S + +R
Sbjct: 1280 VLTELLEQERKKVVDTTKESSRKGWESR 1307
Score = 53.5 bits (127), Expect = 2e-06
Identities = 156/714 (21%), Positives = 254/714 (35%), Gaps = 142/714 (19%)
Query: 658 GQK-WVSRWASLADSYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERADSPAGPE 716
GQK ++++ +L D Y+ T + LGR+ E + + R+ S S E
Sbjct: 35 GQKCFLAQPVTLLDIYTHWQQTSE-LGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEE 93
Query: 717 SSRRSGPGPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQEG 776
+ + P L S S L P S+ + + ++ + + G + P G
Sbjct: 94 AEAETAKATPRLASTNSSVLGADL---PSSMKEKAKAETEKAGKTG-----NSMPHPATG 145
Query: 777 PTWSR--GRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARD 834
T + +SPR EP+ + + + + + AA GQ S
Sbjct: 146 KTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTS- 204
Query: 835 GVYVSANGRMVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSHPLLQD 894
S++ ++ +P P A + +ES ++ A PAPGK ++ P ++
Sbjct: 205 ----SSSDETDVEGKPSVKPA-QVKASSVSTKESPARKAA---PAPGKVGDVT--PQVKG 254
Query: 895 LA---ATRAARMDFHSQDTHLILKETETALA-------ALEARLLSNSVDAECEG----G 940
A A RA + + S+ + + E A A A E L + A +G G
Sbjct: 255 GALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKG 314
Query: 941 STPRPPEDA---------------------LSGDSDVDTASTVSL----RSGKSGP--SP 973
+TP PP A S DS+ +T + +L SGK+ +
Sbjct: 315 ATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAA 374
Query: 974 TTPQPLRAQKEMSPSPPAAQDPGGTAL---------VSAREQSSERQHHPLGPTDMGRGE 1024
+ P +K +P+PP P S+ E+S + P G+
Sbjct: 375 SAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAP 434
Query: 1025 PVRRSAIRRGHRPR-GSLDWPSEERGPVLAHL----PSSDVMASNHET------------ 1067
VR ++ PR G+ P + GP A + D +S+ E+
Sbjct: 435 QVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNA 494
Query: 1068 -------------PEAT-GAGRLGSRRKPAAP----PPSPAAR----EEQSRSSASSQKG 1105
P +T G G LG P P P +P+A+ EE S SS+
Sbjct: 495 AQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEES-- 552
Query: 1106 PQALTRSNSLSTPRPTRASRLRRARLGDASDTEAADGERGSLGNPEPVGRPAAEQAKKLS 1165
S+S PT + + LG+ +A + G P+ G P A Q K
Sbjct: 553 ------SDSSDGEVPTAVAPAQEKSLGNI--LQAKPTSSPAKGPPQKAG-PVAVQVKAEK 603
Query: 1166 RLDILAMPRKRAGSFTGTSDPEAAPARTSFSGRSVELCCASRKPTM--AEARAVSRKAAN 1223
+D + + S +D E APA + A KP + + +A +K
Sbjct: 604 PMDNSESSEESSDS----ADSEEAPA---------AMTAAQAKPALKIPQTKACPKK--- 647
Query: 1224 TATTTGPRQPFSRARSGSARYTSTTQTPRAGSSSRARSRAPGPRDTDDDEEEPD 1277
T TT + R + + R T +P AGSS P + EE D
Sbjct: 648 TNTTASAKVAPVRVGTQAPRKAGTATSP-AGSSPAVAGGTQRPAEDSSSSEESD 700
>gi|166706868 synaptopodin 2-like isoform a [Homo sapiens]
Length = 977
Score = 61.6 bits (148), Expect = 6e-09
Identities = 180/758 (23%), Positives = 257/758 (33%), Gaps = 120/758 (15%)
Query: 430 PKADKRRGPTPADRDRPSVPAPVQAGGRSSGPQRAGSLKREKTEERLGSPSPASRTPARP 489
P ++ G T +D D P+ + R GP R E L S SPA P P
Sbjct: 132 PDSEAYYGETDSDADGPATQEKPRRP-RRRGPTRPTPPGAPPDEVYL-SDSPAEPAPTIP 189
Query: 490 FGSVGRRSRLAQDFMAQCLRESSPAARPSPEKVPPVLPAPLTPHGTSPVGP-------PT 542
SR+ SSP+ PP A L PHG GP P
Sbjct: 190 GPPSQGDSRV-----------SSPSWEDGAALQPPPAEALLLPHGPLRPGPHLIPMVGPV 238
Query: 543 PPPAPTDPQLTKARKQEEDDSLSDAGTYTIETEAQDTEVEEARKMIDQVFGVLESPELSR 602
P P D T +K ++ A E+ Q+ ++EA+ + +L +
Sbjct: 239 PHPVAEDLTTTYTQKAKQ------AKLQRAES-LQEKSIKEAKTKCRTIASLLTAAPNPH 291
Query: 603 ASSATF--RPVIRGDRDESDDGGVAQRMALLQEFASRPLGAAPQAEHQGLPVPGSPGGQK 660
+ + R + G A +E P + E
Sbjct: 292 SKGVLMFKKRRQRAKKYTLVSFGAAAGTGAEEEDGVPPTSESELDEEAFSDARSLTNQSD 351
Query: 661 WVSRWASLADSYSDPGLTE---DGLGRRGGEPEG---SLPVRMRRRLPQLPSERAD-SPA 713
W S + + + + +E GLG + E G L + R+R E A PA
Sbjct: 352 WDSPYLDMELARAGSRASEGQGSGLGGQLSEVSGRGVQLFEQQRQRADSSTQELARVEPA 411
Query: 714 ------GPESSRRSGPGPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRG---PEPGVE 764
G +S R+ PPE PS L P ++ G G P P +
Sbjct: 412 AMLNGEGLQSPPRAQSAPPEAAVLPPSPL-------PAPVASPRPFQPGGGAPTPAPSIF 464
Query: 765 PQDSRRRSP---QEGPTWSRGRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEG 821
+ +R +P + PT + P AP + + + S+ P P G
Sbjct: 465 NRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSG 524
Query: 822 LGQTA----QPSPPARDG-------VYVSANGRMVIQLRPGRSPEPDGPAPAF------- 863
+ A PS P G +Y+ A R V PG +PEP P A
Sbjct: 525 VPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPV---TPGGAPEPPAPPSAAAMTSTAS 581
Query: 864 ------LRQESFTKEPASGPPAPGKPPHISSHPLLQDLAAT----RAARMDFHSQDTHLI 913
LR + + PA GP AP +PP + A T A R Q
Sbjct: 582 IFLSAPLRPSARPEAPAPGPGAP-EPPSAREQRISVPAARTGILQEARRRGTRKQMFRPG 640
Query: 914 LKETETALAALEARLLSNSVDAECEGGSTPRPPEDALS-GDSDVDTASTVSLRSGKSGP- 971
+ET+ + L+ N + GG+ P EDALS G + V RS K+ P
Sbjct: 641 KEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPH 700
Query: 972 -SPTTPQPL--RAQKEMSPS--PPAAQDPGGTALVSAR-EQSSERQHHPLGPTDMGRGEP 1025
+P TP P+ + M+P PP A P L+ ++ P P GRG
Sbjct: 701 VTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGE 760
Query: 1026 V---RRSAIRR-----------GHRPRGSLDWPSEERGPVLAHLPSSDVMASNHETPEAT 1071
+ R+S R G RPR PS LP S + N P
Sbjct: 761 LFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPS---------LPPSWKYSPNIRAPPPI 811
Query: 1072 GAGRLGSRRKPAAPPPSPAAREEQSRSSASSQKGPQAL 1109
L S P A P A+ + R A+ ++G +AL
Sbjct: 812 AYNPLLSPFFPQAARTLPKAQSQGPR--ATPKQGIKAL 847
Score = 35.8 bits (81), Expect = 0.33
Identities = 35/119 (29%), Positives = 44/119 (36%), Gaps = 10/119 (8%)
Query: 416 KKRSQSFTHSPSGDPKADKRRGPTPADRDRPSVPAPVQAGG-----RSSGPQRAGSLKRE 470
K+ + S P +GPTP VP+ G RSSGP A S
Sbjct: 493 KRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYI 552
Query: 471 KTEERLGSPSPASRTPARPFGSVGRRSRLAQDFMAQCLRESSPAARPSPEKVPPVLPAP 529
R +P A PA P S + A F++ LR P+ARP P P P
Sbjct: 553 PAPSRPVTPGGAPEPPAPP--SAAAMTSTASIFLSAPLR---PSARPEAPAPGPGAPEP 606
Score = 33.9 bits (76), Expect = 1.3
Identities = 35/140 (25%), Positives = 47/140 (33%), Gaps = 15/140 (10%)
Query: 426 PSGDPKADKRR--GPTPADRDRPSVPAPVQAGGRSSGPQRAGSLK---REKTEERLGSPS 480
PS P+A P P + P G +R G+ K R EE SP+
Sbjct: 590 PSARPEAPAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPN 649
Query: 481 PASRT-------PARPFGSVGRRSRLAQDFMAQCLRESSPAARPSPEKVP---PVLPAPL 530
P + R G+ A A+ P S + +P P P P+
Sbjct: 650 PELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPM 709
Query: 531 TPHGTSPVGPPTPPPAPTDP 550
P P+ P TPPP P
Sbjct: 710 APKTPPPMTPKTPPPVAPKP 729
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 60.8 bits (146), Expect = 1e-08
Identities = 117/518 (22%), Positives = 174/518 (33%), Gaps = 100/518 (19%)
Query: 415 RKKRSQSFTHSPSGDPKADKRRGPTPADRDRPSVPAPVQAGGRSSGPQRAGSLKREKTEE 474
R+ RS+S ++SP P RR P+P R P P RS P R +R +
Sbjct: 300 RRHRSRSRSYSPRRRPSP--RRRPSPRRRTPPRRMPPPPRHRRSRSPVRR---RRRSSAS 354
Query: 475 RLGSPSPASRTPARPFGSVGRRSRLAQDFMAQCLRESSPAARPSPEK---VPPVLPAPLT 531
GS S +S + +R S ++ + R SP+A P + PP P P T
Sbjct: 355 LSGSSSSSSSSRSR---SPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKT 411
Query: 532 PHGTSPV-------GPPTPPPAPTDPQLTKARKQEEDDSLSDAGTYTIETEAQDTEVEEA 584
H +P + P T ++TK + E+ +S S A + E ++E ++
Sbjct: 412 RHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPR-KVELSESEEDKG 470
Query: 585 RKMI--DQV-----FGVLESPELSRASSATFRPVIRGDRDESDDGGVAQRMALLQEFASR 637
KM D V + S + S++ R R +G V +R ++
Sbjct: 471 GKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSAS 530
Query: 638 PLG-----------------AAPQAEHQGLPVPGSPGGQKWVSRWASLADSYSDPGLTED 680
P + P + P P P ++ + S P
Sbjct: 531 PSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPR--- 587
Query: 681 GLGRRGGEPEGSLPVRMRRRLPQLPSERADSPAGPESSRRSGPGPP-------ELDSEQP 733
RR P P RR P P +R + P RR+ P PP +Q
Sbjct: 588 ---RRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQR 644
Query: 734 SRLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQEGPTWSRGRRSPRAPGEPT 793
S + S GS R PQ ++R SP P R+P+ P
Sbjct: 645 SSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRP------RAPQTSSSPP 698
Query: 794 PASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSANGRMVIQLRPGRS 853
P G + PSP R VS R+
Sbjct: 699 P-------------------VRRGASSSPQRRQSPSPSTRPIRRVS------------RT 727
Query: 854 PEPD------GPAPAFLRQESFTKEPASGP-PAPGKPP 884
PEP P+P +R+ S ++ + P PA KPP
Sbjct: 728 PEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPP 765
Score = 55.8 bits (133), Expect = 3e-07
Identities = 134/617 (21%), Positives = 208/617 (33%), Gaps = 132/617 (21%)
Query: 432 ADKRRGPTPADRDRPSVPAPVQAGGRSSGPQ--RAGSLKREKTEERLGSPSPASRTPARP 489
+D + P P P P+P + + + R S R K+ R S SP+ P R
Sbjct: 242 SDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRR 301
Query: 490 FGSVGRRSRLAQDFMAQCLRESSPAARPSPEKVPPVLPAPLTPHGTSPVGPPTPPPAPTD 549
RSR R SP RPSP + P +P +P PPP
Sbjct: 302 -----HRSRS---------RSYSPRRRPSPRRRP-------SPRRRTPPRRMPPPPRHRR 340
Query: 550 PQLTKARKQEEDDSLSDAGTYTIETEAQDTEVEEARKMIDQVFGVLESPELSRASSATFR 609
+ R++ SLS + + + + ++ + ++ P +R S +
Sbjct: 341 SRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKR-------TSSPPRKTRRLSPSAS 393
Query: 610 PVIRGDRDE-----------SDDGGVAQRMALLQEFASRPLGAAPQAEHQGLPVPGSPGG 658
P R R S + R + S + +H+G SP
Sbjct: 394 PPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSP 453
Query: 659 QKWVSRWASLADSYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERADSPAGPESS 718
R L++S D +GG+ + V+ RR+ + ++++ S +G SS
Sbjct: 454 AP-KPRKVELSESEED----------KGGKMAAADSVQQRRQYRR-QNQQSSSDSGSSSS 501
Query: 719 RRSGPGPPELDSEQPSRLF---GQEELDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQE 775
+ E+P R G+ S S R + P+ RRRSP
Sbjct: 502 S---------EDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSP 552
Query: 776 GPTWSRGRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDG 835
PT R RRSP +P P R P P + PSPP R
Sbjct: 553 PPT--RRRRSP-SPAPPPRR-------------RRTPTPPP-------RRRTPSPPPR-- 587
Query: 836 VYVSANGRMVIQLRPGRSPEPDGPAPAFLRQESFTKEP----ASGPP------APGKPP- 884
RSP P +P R+ S + P AS PP +P PP
Sbjct: 588 ---------------RRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPK 632
Query: 885 -HISSHPLLQDLAATRAARMDFHSQDTHLILKETETALAALEARLLSNSVDAECEGGSTP 943
+S P + ++ R H K + + + EAR S +P
Sbjct: 633 RRVSHSPPPKQRSSPVTKRRSPSLSSKH--RKGSSPSRSTREAR----SPQPNKRHSPSP 686
Query: 944 RPPEDALSGDSDVDTASTVSLRSGKSGPSPT---------TPQPLRAQKEMSPSPPAAQD 994
RP S S + PSP+ TP+P + +K SPSP + +
Sbjct: 687 RPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRR 746
Query: 995 PGGTALVSAREQSSERQ 1011
+ VS + + ++
Sbjct: 747 VSSSRSVSGSPEPAAKK 763
Score = 55.1 bits (131), Expect = 5e-07
Identities = 133/618 (21%), Positives = 206/618 (33%), Gaps = 112/618 (18%)
Query: 100 RVQHRVPEEALKHEKYTSQL-QVSVKGLAPKRSEA--------LPEHTPYCEASNPRPEK 150
R + R P A + ++ T +L + SVK P EA +P+ P E P PEK
Sbjct: 204 RTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEK 263
Query: 151 GDRRPGTEAASYRTPLYGQPSWWGEDDGSTLPDAQRQGEPYPERPKGPVQQDGELHGFRA 210
++ E +T + S R P RP+ + + R
Sbjct: 264 NSKK---EKEKEKTRPRSRSR-------SKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRR 313
Query: 211 PAEPQGCSFRREPSYFEIPTKETPQPSQPPEVPAHEMPTKDAEAGGGGAAPVVQSHASFT 270
P RR PS P + TP PP P H +A + S +S +
Sbjct: 314 RPSP-----RRRPS----PRRRTPPRRMPPP-PRHRRSRSPVRRRRRSSASLSGSSSSSS 363
Query: 271 IEFDDCSPGKMKIKDHITKFSLRQRRPPGKEATPGEMVSAETKVADWLVQNDPSLLHRVG 330
P K + T R+ R A+P + A P H
Sbjct: 364 SSRSRSPPKKPPKR---TSSPPRKTRRLSPSASPPRRRHRPSPPAT----PPPKTRHSPT 416
Query: 331 PGDDRHSTKSDLPVHTRTLKGH--KHEDGTQSDSEDPLAKAASAAGVPLE-------ASG 381
P + KS + V G KH+ + +S P K E A+
Sbjct: 417 PQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAA 476
Query: 382 EQVRLQRQIKRDPQELLHNQQAFVIEFFDEDTP------------RKKRSQSFTHSPSG- 428
+ V+ +RQ +R Q+ + + +++ P R++ S S + SPS
Sbjct: 477 DSVQQRRQYRRQNQQ--SSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPR 534
Query: 429 ------DPKADKRRGPTPADRDRPSVPAPVQAGGRSSGPQRAGSLKREKTEERLGSPSPA 482
P+ +RR P+P R P+P + P+R R +P P
Sbjct: 535 KRQKETSPRGRRRRSPSPPPTRRRRSPSP------APPPRR----------RRTPTPPPR 578
Query: 483 SRTPARPFGSVGRRSRLAQDFMAQCLRESSPAARPSPEKVPPVLPAPLTPHGTSPVGPP- 541
RTP+ P RRS + + R SP+ P K P P SP PP
Sbjct: 579 RRTPSPP---PRRRSPSPRRYSPPIQRRYSPS---PPPKRRTASPPPPPKRRASPSPPPK 632
Query: 542 -----TPPPAPTDPQLTKAR------KQEEDDSLSDAGTYTIETEAQDTEVEEARKMIDQ 590
+PPP +TK R K + S S + + R Q
Sbjct: 633 RRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQ 692
Query: 591 VF--------GVLESPELSRASSATFRPVIRGDR----DESDDGGVAQRMALLQEFASRP 638
G SP+ ++ S + RP+ R R + ++ + +SR
Sbjct: 693 TSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRS 752
Query: 639 LGAAPQAEHQGLPVPGSP 656
+ +P+ + P P SP
Sbjct: 753 VSGSPEPAAKKPPAPPSP 770
Score = 49.3 bits (116), Expect = 3e-05
Identities = 80/308 (25%), Positives = 107/308 (34%), Gaps = 33/308 (10%)
Query: 1004 REQS-SERQHHPLGPTDMGRGEPVRRSAIRRG-----HRPRGSLDWPSEERGPVLAHLPS 1057
RE+S S R+ P+ R PVRR R HR + P+ E+ LP
Sbjct: 166 RERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPE 225
Query: 1058 SDVMASNHETPEATGAGRLGSRRKPAA-PPPSPAAREEQSRSSASSQKGPQALTRSNSLS 1116
V EAT + KP P P + E+ S+ +K + +RS S S
Sbjct: 226 PSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEK-TRPRSRSRSKS 284
Query: 1117 -------TPRPTRASRLRRARLGDASD-TEAADGERGSLGNPEPVGRPAAEQAKKLSRLD 1168
+P TR R R+R S + R S P R + SR
Sbjct: 285 RSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSP 344
Query: 1169 ILAMPRKRAGSFTGTSD----------PEAAPARTSFSGRSVELCCASRKPTMAEARAVS 1218
+ R+ + S +G+S P+ P RTS R S P R
Sbjct: 345 V-RRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSP 403
Query: 1219 RKAANTATTTGPR-QPFSRAR----SGSARYTSTTQTPRAGSSSR-ARSRAPGPRDTDDD 1272
T P Q +R R S S TS T G+ R + S AP PR +
Sbjct: 404 PATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELS 463
Query: 1273 EEEPDPYG 1280
E E D G
Sbjct: 464 ESEEDKGG 471
Score = 49.3 bits (116), Expect = 3e-05
Identities = 90/423 (21%), Positives = 142/423 (33%), Gaps = 60/423 (14%)
Query: 958 TASTVSLRSGKSGPSPTTPQPLRAQKEMSPSPPAAQDPGG--TALVSAREQSSERQHHPL 1015
T+ V+ G +P P + E+S S +D GG A S +++ R+ +
Sbjct: 435 TSGKVTKHKGTEKRESPSPAPKPRKVELSESE---EDKGGKMAAADSVQQRRQYRRQNQQ 491
Query: 1016 GPTDMGRGEPVRRSAIRRGHRPRGSLDWPSEERGPVLAHLPSSDVMASNHETPEATGAGR 1075
+D G +R H G E G H PS S + + T
Sbjct: 492 SSSDSGSSSSSEDERPKRSHVKNG-------EVGRRRRHSPSRSASPSPRKRQKETSPR- 543
Query: 1076 LGSRRKPAAPPPSPAAREEQSRSSASSQKGPQALTRSNSLSTPRPTRASRLRRARLGDAS 1135
G RR+ +PPP+ R ++ P R + S P R+ RR
Sbjct: 544 -GRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRR------- 595
Query: 1136 DTEAADGERGSLGNPEPVGRPAAEQAKKLSRLDILAMPRKRAGSFTGTSDPEAAPARTSF 1195
+ +R +P P R A+ R P++R S P +
Sbjct: 596 --YSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSH----SPPPKQRSSPVT 649
Query: 1196 SGRSVELCCASRKPTMAEARAVSRKAANTATTTGPRQPFSRARSGSARYTSTTQTP--RA 1253
RS L RK + ++ A + P + S + A TS++ P R
Sbjct: 650 KRRSPSLSSKHRKGSSPS------RSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRG 703
Query: 1254 GSSSRARSRAPGPRDTDDDEEEPDPYGFIVQTAEIAEIARLSQ--TLVKDVAILAQEIHD 1311
SSS R ++P P T I ++R + + K + Q +
Sbjct: 704 ASSSPQRRQSPSP-----------------STRPIRRVSRTPEPKKIKKAASPSPQSVRR 746
Query: 1312 VAGDGDTLGSSEPAHSASLSNMPSTPASTISAREELVQRIPEASLNFQKVP-PGSLNSRD 1370
V+ GS EPA + P P S + ++ P + K P P R+
Sbjct: 747 VSSSRSVSGSPEPA-----AKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRN 801
Query: 1371 FDQ 1373
DQ
Sbjct: 802 SDQ 804
Score = 46.2 bits (108), Expect = 2e-04
Identities = 142/629 (22%), Positives = 206/629 (32%), Gaps = 75/629 (11%)
Query: 596 ESPELSRASSATFRPVIRGDRDESDDGGVAQRMALLQEFASRPLGAAPQAEHQGLPVPGS 655
++PEL S P ++ SD V + + + P + + + + P S
Sbjct: 219 KTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRS 278
Query: 656 PGGQKWVSRWASLADSYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERADSPAGP 715
K SR S + S++ P RR S R R + PS R +P
Sbjct: 279 RSRSKSRSRTRSRSPSHTRPR-------RRHRSRSRSYSPRRRPSPRRRPSPRRRTPP-- 329
Query: 716 ESSRRSGPGPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGP------EPGVEPQDSR 769
RR P P S P R + S +S S R P P+ +R
Sbjct: 330 ---RRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTR 386
Query: 770 RRSPQEGPTWSRGRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPG-------DGEGL 822
R SP P R R SP A P Q+ SR + +PG +G
Sbjct: 387 RLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSV-SPGRTSGKVTKHKGT 445
Query: 823 GQTAQPSP-PARDGVYVSANGRMVIQLRPGRSPEPDG-PAPAFLRQESFTKEPASGPPAP 880
+ PSP P V +S + + + G+ D R+++ SG +
Sbjct: 446 EKRESPSPAPKPRKVELSESE----EDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSS 501
Query: 881 GKPPHISSHPLLQDLAATRAARMDFHSQDTHLILKETETALAALEARLLSNSVDAECEGG 940
+ + R S ++ ET+ R S
Sbjct: 502 SEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSP 561
Query: 941 STPRPPEDALSGDSDVDTASTVSLRSGKSGPSPTTPQPLRAQKEMSPSPP-----AAQDP 995
S P PP + T S + PSP P Q+ SPSPP A+ P
Sbjct: 562 S-PAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSP-PIQRRYSPSPPPKRRTASPPP 619
Query: 996 GGTALVSAREQSSERQHHPLGPTDMGRGEPV--RRSAIRRGHRPRGSLDWPSEERGPVLA 1053
S R H P R PV RRS +GS S R A
Sbjct: 620 PPKRRASPSPPPKRRVSH--SPPPKQRSSPVTKRRSPSLSSKHRKGS----SPSRSTREA 673
Query: 1054 HLPSSDVMASNHETPEATGAGRLGSRRKPAAPPP--SPAAREEQSRSSASSQKGP-QALT 1110
P + S P A + ++PPP A+ Q R S S P + ++
Sbjct: 674 RSPQPNKRHSPSPRPRAP--------QTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVS 725
Query: 1111 RSNSLSTPRPTRASRLRRARLGDASDTEAADGERGSLGNPEPVGR-----PAAEQAKKLS 1165
R TP P ++++A R G+PEP + P+ Q++ S
Sbjct: 726 R-----TPEP---KKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPS 777
Query: 1166 RLDILAMPRKRAGSFTGTSDPEAAPARTS 1194
A+P K+A S T P +P R S
Sbjct: 778 TNWSPAVPVKKAKSPT----PSPSPPRNS 802
Score = 43.1 bits (100), Expect = 0.002
Identities = 93/465 (20%), Positives = 158/465 (33%), Gaps = 56/465 (12%)
Query: 129 KRSEALPEHTPY-CEASNPRPEKGDRRPGTEAASYRTPLYGQPSWWGEDDGSTLPDAQRQ 187
KR P P E S +KG + ++ R Q D GS+
Sbjct: 447 KRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSED-- 504
Query: 188 GEPYPERPKGPVQQDGELHGFRAPAEPQGCS---------------FRREPSYFEIPTKE 232
ERPK ++GE+ R + + S RR PS +
Sbjct: 505 -----ERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRR 559
Query: 233 TPQPSQPPEVPAHEMPTKDAEAGGGGAAPVVQSHAS------FTIEFDDCSPGKMKIKDH 286
+P P+ PP PT P +S + + P K +
Sbjct: 560 SPSPAPPPR--RRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASP 617
Query: 287 ITKFSLRQRRPPGKEATPGEMVSAETKVADWLVQNDPSLL--HRVGPGDDRHSTKSDLPV 344
R P + + + + + PSL HR G R + ++ P
Sbjct: 618 PPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQ 677
Query: 345 HTRTLKGHKHEDGTQ-SDSEDPLAKAASAAGVPLEASGEQVRLQRQIKRDPQELLHNQQA 403
+ Q S S P+ + AS++ ++ R R++ R P+ + A
Sbjct: 678 PNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAA 737
Query: 404 FVIEFFDEDTPRKKRSQSFTHSPSGDPKADKRRGPTPADRDRPSVPAPVQAGGRSSGPQR 463
+P+ R S + S SG P+ PA + P+ P+PVQ+ S+
Sbjct: 738 -------SPSPQSVRRVSSSRSVSGSPE--------PAAKKPPAPPSPVQSQSPSTNWSP 782
Query: 464 AGSLKREKTEERLGSPSPASRTPARPFGSVGRRSRLAQDFMAQCLRESSPAARPSPEK-V 522
A +K+ K+ +PSP+ + G G++ + +D + ++ + EK V
Sbjct: 783 AVPVKKAKSP----TPSPSPPRNSDQEGG-GKKKKKKKDKKHKKDKKHKKHKKHKKEKAV 837
Query: 523 PPVLPAPLTPHGTSPVGPPTPPPAP-TDPQLTKARKQEEDDSLSD 566
A +TP + P P+ K + E +D+L D
Sbjct: 838 AAAAAAAVTPAAIAAATTTLAQEEPVAAPEPKKETESEAEDNLDD 882
>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
Length = 1626
Score = 58.5 bits (140), Expect = 5e-08
Identities = 134/538 (24%), Positives = 180/538 (33%), Gaps = 70/538 (13%)
Query: 648 QGLP-VPGSPGGQKWVSRWASLADSYSDPGLTEDGLGRRGGEP--EGSLPVRMRRRLP-- 702
+G P +PGSPG S DPG+ G G P +GS R P
Sbjct: 1027 RGAPGIPGSPG-------------SRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGP 1073
Query: 703 QLPSERADSPAGPESSRRSGPGPPELDSE-QPSRLFGQEELDPDSLSDASGSDGGRGPEP 761
Q P+ R +P P R PG P L S P + L D +D G P
Sbjct: 1074 QGPAGRDGAPGNP--GERGPPGKPGLSSLLSPGDI---NLLAKDVCNDCPPGPPGLPGLP 1128
Query: 762 GVEPQDSRRRSP-QEGPTWSRGRRSPRAPGEPTPASFF-----IGDQNGDAVLSRK-PLA 814
G + P +EG +G P PG P P G++ D + +K
Sbjct: 1129 GFKGDKGVPGKPGREGTEGKKGEAGP--PGLPGPPGIAGPQGSQGERGADGEVGQKGDQG 1186
Query: 815 APGDGEGLGQTAQPSPPARDGVYVSANGRMVIQLRPGRS--PEPDGPA--PAFLRQESFT 870
PG +G P PP DG+ A G IQ PG+ P P GP+ P +E
Sbjct: 1187 HPGVPGFMGPPGNPGPPGADGI-AGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEG-- 1243
Query: 871 KEPASGPPAPGKPPHISSHPLLQDLAATRA-ARMDFHSQDTHLILKETETALAALEAR-- 927
KE G P P P + P L R H+ D+ E+ L +
Sbjct: 1244 KEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEG 1303
Query: 928 LLSNSVDAECEGGSTPRPPEDALSGDSDVDTASTVSLRSGKSGPSPTTPQPLRAQKEMSP 987
L D G P+ P + + G+ GPS T Q + SP
Sbjct: 1304 LPGKDGDTGPTGPQGPQGPRGPPGKNGSPGS-------PGEPGPSGTPGQKGSKGENGSP 1356
Query: 988 SPPAAQDPGGTALVSAREQSSERQHHPLGPTDMG----RGEPVRRSAIRRGHRPRGSLDW 1043
P P G + ++ P P + G RG+P I+ P G
Sbjct: 1357 GLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDP----GIKGDKGPPGGKGQ 1412
Query: 1044 PSEERGPVLAHLPSSDVMASNHETPEATGAGRLGSRRKPAAP---PPSPAAREEQSRSSA 1100
P + P H + +M E G G +P P SP+ E R
Sbjct: 1413 PGDPGIP--GHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSM--ETLRRLI 1468
Query: 1101 SSQKGPQALTRSNSLSTPRPTRASRLRRARLGDAS--DTEAADGERGSLGNPEPVGRP 1156
+ G Q TR L P + + R G + G G +G P GRP
Sbjct: 1469 QEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEP---GRP 1523
Score = 45.4 bits (106), Expect = 4e-04
Identities = 97/367 (26%), Positives = 123/367 (33%), Gaps = 67/367 (18%)
Query: 532 PHGTSPVGPPTPPPAPTDPQLTKARKQEEDDSLSDAGTYTIETEAQDTEVEEARKMIDQV 591
P G V T PP P PQ E+ L TI E E V
Sbjct: 439 PSGPCQVTVVTEPPPPPPPQRPPTPGSEQIGFLK-----TINCSCPAGEKGEMG-----V 488
Query: 592 FGVLESPELSRASSATFRPVIRGDRDESDDGGVAQRMALLQEFASRPLGAAPQAEHQGLP 651
G + P A G + E D G+ P G + E L
Sbjct: 489 AGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGIG------------PFGQGEKGEKGSLG 536
Query: 652 VPGSPG--GQKWVSRWASLADSYSDPGLTEDGLGRRGGEPEGSLPVRMRR-RLPQLPSER 708
+PG PG G K + +PGL + +G RG + LP R P L ER
Sbjct: 537 LPGPPGRDGSKGM---RGEPGELGEPGLPGE-VGMRGPQGPPGLPGPPGRVGAPGLQGER 592
Query: 709 ADSPAGPESSRRSGPGPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGP--EPGVEPQ 766
+ E R G P +P Q P ++ G G GP PGV
Sbjct: 593 GEKGTRGEKGERGLDGFP----GKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGS 648
Query: 767 DSRRRSPQEGPTWSRGRRSPR----APGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGL 822
+ QEG +G PR APG P A IG + D P +GL
Sbjct: 649 VVQ----QEGLKGEQGAPGPRGHQGAPG-PPGARGPIGPEGRD---------GPPGLQGL 694
Query: 823 -GQTAQPSPPARDGVYVSANGRMVIQLRPGRS--PEPDGP--APAFLRQESFTKEPASGP 877
G+ PP G+ + +Q PG P P GP +P + F +P GP
Sbjct: 695 RGKKGDMGPPGIPGL-------LGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKP--GP 745
Query: 878 PAPGKPP 884
P P PP
Sbjct: 746 PGPTGPP 752
>gi|50301232 synaptopodin 2-like isoform b [Homo sapiens]
Length = 753
Score = 58.5 bits (140), Expect = 5e-08
Identities = 113/450 (25%), Positives = 165/450 (36%), Gaps = 67/450 (14%)
Query: 689 PEGSLPVRMRRRLPQLPSERADSPAGPESSRRSGPGPPELDSEQPSRLFGQEELDPDSLS 748
P LP + P P A +PA +R + P P L ++P+ P +
Sbjct: 212 PPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTT--SVIFRPLAPK 269
Query: 749 DASGSDGGRGPEPGVEPQDSRRRSPQEGPTWSRGRRSPRAPGEPTPASFFIGDQNGDAVL 808
A+ S GG P P P + P P+++ G S AP +P++ ++ V
Sbjct: 270 RANDSLGGLSPAP---PPFLSSQGPTPLPSFTSGVPS-HAPVSGSPST----PRSSGPVT 321
Query: 809 SRKPLAAPGDGEGL---GQTAQPSPPARDGVYVSANGRMVIQLRPGRSPEPDGPAPAFLR 865
+ L P + G P+PP+ + +A+ + LRP PE
Sbjct: 322 ATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPE---------- 371
Query: 866 QESFTKEPASGPPAPGKPPHISSHPLLQDLAAT----RAARMDFHSQDTHLILKETETAL 921
PA GP AP +PP + A T A R Q +ET+ +
Sbjct: 372 ------APAPGPGAP-EPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSP 424
Query: 922 AALEARLLSNSVDAECEGGSTPRPPEDALS-GDSDVDTASTVSLRSGKSGP--SPTTPQP 978
L+ N + GG+ P EDALS G + V RS K+ P +P TP P
Sbjct: 425 NPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPP 484
Query: 979 L--RAQKEMSPS--PPAAQDPGGTALVSAR-EQSSERQHHPLGPTDMGRGEPV---RRSA 1030
+ + M+P PP A P L+ ++ P P GRG + R+S
Sbjct: 485 MAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSR 544
Query: 1031 IRR-----------GHRPRGSLDWPSEERGPVLAHLPSSDVMASNHETPEATGAGRLGSR 1079
R G RPR PS LP S + N P L S
Sbjct: 545 ADRYVVEGTPGPGLGPRPRSPSPTPS---------LPPSWKYSPNIRAPPPIAYNPLLSP 595
Query: 1080 RKPAAPPPSPAAREEQSRSSASSQKGPQAL 1109
P A P A+ + R A+ ++G +AL
Sbjct: 596 FFPQAARTLPKAQSQGPR--ATPKQGIKAL 623
Score = 35.8 bits (81), Expect = 0.33
Identities = 35/119 (29%), Positives = 44/119 (36%), Gaps = 10/119 (8%)
Query: 416 KKRSQSFTHSPSGDPKADKRRGPTPADRDRPSVPAPVQAGG-----RSSGPQRAGSLKRE 470
K+ + S P +GPTP VP+ G RSSGP A S
Sbjct: 269 KRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYI 328
Query: 471 KTEERLGSPSPASRTPARPFGSVGRRSRLAQDFMAQCLRESSPAARPSPEKVPPVLPAP 529
R +P A PA P S + A F++ LR P+ARP P P P
Sbjct: 329 PAPSRPVTPGGAPEPPAPP--SAAAMTSTASIFLSAPLR---PSARPEAPAPGPGAPEP 382
Score = 33.9 bits (76), Expect = 1.3
Identities = 35/140 (25%), Positives = 47/140 (33%), Gaps = 15/140 (10%)
Query: 426 PSGDPKADKRR--GPTPADRDRPSVPAPVQAGGRSSGPQRAGSLK---REKTEERLGSPS 480
PS P+A P P + P G +R G+ K R EE SP+
Sbjct: 366 PSARPEAPAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPN 425
Query: 481 PASRT-------PARPFGSVGRRSRLAQDFMAQCLRESSPAARPSPEKVP---PVLPAPL 530
P + R G+ A A+ P S + +P P P P+
Sbjct: 426 PELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPM 485
Query: 531 TPHGTSPVGPPTPPPAPTDP 550
P P+ P TPPP P
Sbjct: 486 APKTPPPMTPKTPPPVAPKP 505
>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
Length = 1312
Score = 57.0 bits (136), Expect = 1e-07
Identities = 189/810 (23%), Positives = 268/810 (33%), Gaps = 207/810 (25%)
Query: 510 ESSPAARPSPEKVPPVLPAPLTPHGTSPVGPPTPPP-APTDPQLTK-------------- 554
+ PA P+P P+P +P +SP PP PPP AP P +
Sbjct: 181 DGGPAPPPAPSSASSS-PSP-SPSSSSPSPPPPPPPPAPPAPPAPRFDIYDPFHPTDEAY 238
Query: 555 ----ARKQEED-------DSLSDAGTYTIETEAQDTEVEEARKMIDQVFGVLESPELSRA 603
A +Q+ D + S AGT + E E ++ E EE + ++ E LS++
Sbjct: 239 SPPPAPEQKYDPFEPTGSNPSSSAGTPSPEEEEEEEEEEEEEEEDEE-----EEEGLSQS 293
Query: 604 SSATFRPVIRGDRDESDDGGVAQRMALLQEFASRPLGAAPQAEHQGLPVPGSPGGQKWVS 663
S R G+ +L Q+F Q P PG+P
Sbjct: 294 IS----------RISETLAGIYDDNSLSQDFPGDESPRPDAQPTQPTPAPGTP------- 336
Query: 664 RWASLADSYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERADSPAGPESSRRSGP 723
DS DG RR G+ R + A A P P
Sbjct: 337 ---PQVDS-----TRADGAMRRRVFVVGTEAEACREGKVSVEVVTAGGAALPP------P 382
Query: 724 GPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQEGPTWSRGR 783
P DSE Q E +P L+ + GGR P + P P
Sbjct: 383 LLPPGDSEIEEGEIVQPEEEP-RLALSLFRPGGRAARPTPAASATPTAQPLPQPP----- 436
Query: 784 RSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEG-----LGQTAQPSPPARDGVY- 837
+PRAP GD LS L A DGEG LG+ A P+PPA D +
Sbjct: 437 -APRAP-------------EGDDFLS---LHAESDGEGALQVDLGEPA-PAPPAADSRWG 478
Query: 838 -VSANGRMVIQLRP---GRSPEP-DGPAPAFL-------------RQESFTKEPAS---- 875
+ +++ Q R RSP P PAPA ++ KE AS
Sbjct: 479 GLDLRRKILTQRRERYRQRSPSPAPAPAPAAAAGPPTRKKSRRERKRSGEAKEAASSSSG 538
Query: 876 ---GPPAPGKPPHISSHPLLQDLAATRAARMDFHSQDTHLILKETETALAALEARLLSNS 932
PPAP P H +R + H+ + A +R S S
Sbjct: 539 TQPAPPAPASPWDSKKH-------RSRDRKPGSHASSS-----------ARRRSRSRSRS 580
Query: 933 VDAECEGGSTPRPPEDALSGDSDVDTASTVSLRSGKSGPSPTTPQPLRAQKEMSPSPPAA 992
ST R R G S S + + R ++ SP PPA
Sbjct: 581 RSTRRRSRSTDR--------------------RRGGSRRSRSREKRRRRRRSASP-PPA- 618
Query: 993 QDPGGTALVSAREQSSERQHHPLGPTDMGRGEPVRRSAIRRGHRPRGSLDWPSEERGPVL 1052
++ SS R+ H D G + ++ + RG + G E+ P
Sbjct: 619 ---------TSSSSSSRRERHRGKHRDGGGSKKKKKRSRSRGEKRSGD----GSEKAPAP 665
Query: 1053 AHLPSSDVMASNHETPEATGAGRLGSRRKPAAPPPSPAAREEQ----------SRSSASS 1102
A PS +T G SRR+ A PP + R S
Sbjct: 666 APPPSG-----------STSCGDRDSRRRGAVPPSIQDLTDHDLFAIKRTITVGRLDKSD 714
Query: 1103 QKGP----------QALTRSNSLS-TPRPTRASRLRRARLGDASDTEAADGERGSLGNPE 1151
+GP + L S LS R ++S+ R R G AS + ++ E+GS
Sbjct: 715 PRGPSPAPASSPKREVLYDSEGLSGEERGGKSSQKDRRRSGAAS-SSSSSREKGSRRKAL 773
Query: 1152 PVGRPAAEQAKKLSRLDILAMPRKRAGSFTGTSDPEAAPARTSFSGRSVELCCASRKPTM 1211
G ++ + R R S + P P + S C+SRK +
Sbjct: 774 DGGDRDRDRDRDRDRDRSSKKARPPKESAPSSGPPPKPPVSSGSGSSSSSSSCSSRKVKL 833
Query: 1212 AEARAVSRKAANTATTTGPRQPFSRARSGS 1241
AV + ++TT P + + A GS
Sbjct: 834 QSKVAVLIREGVSSTT--PAKDAASAGLGS 861
Score = 52.8 bits (125), Expect = 3e-06
Identities = 135/593 (22%), Positives = 198/593 (33%), Gaps = 130/593 (21%)
Query: 702 PQLPSERADSPAGPESSRRSGPGPPELDSEQPSRLFGQEEL-DPDSLSDASGSDGGRGPE 760
P PS + SP+ SS P PP P+ + ++ DP +D + S P
Sbjct: 187 PPAPSSASSSPSPSPSSSSPSPPPPPPPPAPPAPPAPRFDIYDPFHPTDEAYS-----PP 241
Query: 761 PGVEPQDSRRRSPQEGPTWSRGRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGE 820
P E + P+ S G SP E ++ D + E
Sbjct: 242 PAPEQKYDPFEPTGSNPSSSAGTPSPEEEEEEEEEE---EEEEEDEE----------EEE 288
Query: 821 GLGQTAQPSPPARDGVYVSANGRMVIQLRPG-RSPEPDGPAPAFLRQESFTKEPASGPPA 879
GL Q+ G+Y + + Q PG SP PD +P PA
Sbjct: 289 GLSQSISRISETLAGIY---DDNSLSQDFPGDESPRPDA-------------QPTQPTPA 332
Query: 880 PGKPPHISSHPLLQDLAATRAARMDFHSQDTHLILKETETALAALEARLLSNSVDAECEG 939
PG PP + S TRA + + + TE A A E ++ SV+ G
Sbjct: 333 PGTPPQVDS---------TRADG----AMRRRVFVVGTE-AEACREGKV---SVEVVTAG 375
Query: 940 GSTPRPPEDALSGDSDVDTASTVS-----------LRSGKSGPSPTTPQPLRAQKEMSPS 988
G+ PP GDS+++ V R G PT + P
Sbjct: 376 GAA-LPPPLLPPGDSEIEEGEIVQPEEEPRLALSLFRPGGRAARPTPAASATPTAQPLPQ 434
Query: 989 PPAAQDPGGTALVSAREQSSERQHHPLGPTDMGRGEPVRRSAIRRGHRPRGSLDWPSEER 1048
PPA + P G +S +S + D+G P +A R G LD +
Sbjct: 435 PPAPRAPEGDDFLSLHAESDGEGALQV---DLGEPAPAPPAADSRW----GGLDLRRK-- 485
Query: 1049 GPVLAHLPSSDVMASNHETPEATGAGRLGSRRKPAAPPPSPAAREEQSRSSASSQKGPQA 1108
++ E R R AP P+PAA GP
Sbjct: 486 -----------ILTQRRE--------RYRQRSPSPAPAPAPAA-----------AAGP-- 513
Query: 1109 LTRSNSLSTPRPTR-ASRLRRARLGDASDTEAADGERGSLGNPEPVGRPAAEQAKKLSRL 1167
PTR SR R R G+A EAA G+ P P + +KK
Sbjct: 514 -----------PTRKKSRRERKRSGEAK--EAASSSSGT--QPAPPAPASPWDSKKHRSR 558
Query: 1168 DILAMPRKRAGSFTGTSDPEAAPART-SFSGRSVELCCASRKPTMAEARAVSRKAANTAT 1226
D ++ GS +S + +R+ S S R R+ +R+ ++ +
Sbjct: 559 D------RKPGSHASSSARRRSRSRSRSRSTRRRSRSTDRRRGGSRRSRSREKRRRRRRS 612
Query: 1227 TTGPRQPFSRARSGSARYTSTTQTPRAGSSSRARSRAPG-PRDTDDDEEEPDP 1278
+ P S + S R+ + + RSR+ G R D E+ P P
Sbjct: 613 ASPPPATSSSSSSRRERHRGKHRDGGGSKKKKKRSRSRGEKRSGDGSEKAPAP 665
Score = 32.7 bits (73), Expect = 2.8
Identities = 67/318 (21%), Positives = 102/318 (32%), Gaps = 62/318 (19%)
Query: 229 PTKETPQPSQPPEVPAH-----------------------EMPTKDAEAGGGGAAPVVQS 265
PT+ TP P PP+V + ++ + AGG P +
Sbjct: 326 PTQPTPAPGTPPQVDSTRADGAMRRRVFVVGTEAEACREGKVSVEVVTAGGAALPPPLLP 385
Query: 266 HASFTIEFDDCSPGKMKIKDHITKFSLRQRRPPGKEATPGEMVSAETKVADWLVQ----- 320
IE G++ + + +L RP G+ A P SA T A L Q
Sbjct: 386 PGDSEIE-----EGEIVQPEEEPRLALSLFRPGGRAARPTPAASA-TPTAQPLPQPPAPR 439
Query: 321 ----NDPSLLHRVGPGDDR---------------HSTKSDLPVHTRTLKGHKHEDGTQSD 361
+D LH G+ S L + + L + +S
Sbjct: 440 APEGDDFLSLHAESDGEGALQVDLGEPAPAPPAADSRWGGLDLRRKILTQRRERYRQRSP 499
Query: 362 SEDPLAKAASAAGVPLEASGEQVRLQR-QIKRDPQELLHNQQAFVIEFFDEDTPRKKRSQ 420
S P A+AAG P + R + + K Q A D+ K+ +
Sbjct: 500 SPAPAPAPAAAAGPPTRKKSRRERKRSGEAKEAASSSSGTQPAPPAPASPWDS---KKHR 556
Query: 421 SFTHSPSGDPKADKRRGPTPADRDRPSVPAPVQAGGRSSGPQRAGSLKREKTEERLGSPS 480
S P + RR R R + R G +R+ S ++ + R SP
Sbjct: 557 SRDRKPGSHASSSARRRSRSRSRSRSTRRRSRSTDRRRGGSRRSRSREKRRRRRRSASPP 616
Query: 481 PASRTPARPFGSVGRRSR 498
PA+ + S RR R
Sbjct: 617 PATSS-----SSSSRRER 629
>gi|21314720 Smad nuclear interacting protein [Homo sapiens]
Length = 396
Score = 57.0 bits (136), Expect = 1e-07
Identities = 35/94 (37%), Positives = 48/94 (51%), Gaps = 11/94 (11%)
Query: 16 HRLPRELIFVGREECELMLQSRSVDKQHAVINYDQ-----------DRDEHWVKDLGSLN 64
HR L+ R ++ + S KQHAV Y R + ++ DLGS N
Sbjct: 276 HRQSAYLLGRHRRIADIPIDHPSCSKQHAVFQYRLVEYTRADGTVGRRVKPYIIDLGSGN 335
Query: 65 GTFVNDMRIPDQKYVTLKLNDVIRFGYDSNMYVL 98
GTF+N+ RI Q+Y LK DV++FG+ S YVL
Sbjct: 336 GTFLNNKRIEPQRYYELKEKDVLKFGFSSREYVL 369
>gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 [Homo
sapiens]
Length = 2231
Score = 57.0 bits (136), Expect = 1e-07
Identities = 149/715 (20%), Positives = 232/715 (32%), Gaps = 126/715 (17%)
Query: 641 AAPQAEHQGLPVPGSPGGQKWVSRWASLADSYSDPGLTEDGLGRRGGE---PEGSLPVRM 697
++P+ + G+ + GG +S+ A+ G G R G+ P G+ P
Sbjct: 311 SSPRQQGGGMMMGPGGGGAASLSKAAA--------GSAAGGFQRFAGQNQHPSGATPTLN 362
Query: 698 RRRLPQLPSERADSPAGPESSRRSGPGPPELDSEQPSRLFG------QEELDPDSLSDAS 751
+ P R+ + PE S S P PP + + G Q D
Sbjct: 363 QLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMG 422
Query: 752 GSDGGRGPEPGVEPQDSR-RRSP-QEGPTWSRGRRSPRAP----------------GEPT 793
P Q S SP GPT R + SP P +P
Sbjct: 423 AQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQ 482
Query: 794 PASFFIGDQNGDAVLSRKPLA----APGDGEGLGQTAQPSPPARDGVYVSANGRMVIQLR 849
+S + G G R P+ PG G+ Q PP VS + Q
Sbjct: 483 QSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPY 542
Query: 850 PGRSPEPDGPAP-----------AFLRQESFTKE---PASGPP-APGKPPHISSHPLLQD 894
+ P+P P + Q+ ++E S PP APGKP H
Sbjct: 543 YSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNH--------- 593
Query: 895 LAATRAARMDFHSQDTHLILKETETALAALEARL----------LSNSVDAECEGGSTPR 944
+D +LI +E ++L L + LS++V A GST
Sbjct: 594 -------------EDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSA---SGSTSS 637
Query: 945 PPEDALSGDSDVDTASTVSLRSGKSGPSPT-TPQPLRAQKEMSPSPPAAQDPGGTALVSA 1003
+ + S ++ L S GPSP+ P+ + + S A PG
Sbjct: 638 QGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQP 697
Query: 1004 REQSSERQHHP-LGPTDMGRGEPVRRSAIRRGHRPRGSLDWPSEERGPVLAHLPS--SDV 1060
SE HP L + M P R + R + ++ GP ++ PS +
Sbjct: 698 PGSQSESSSHPALSQSPM----PQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQM 753
Query: 1061 MASNHETPEATGAGRLGSRRKPAAP------PPSPAAREEQSRSSASSQKGPQALTRSNS 1114
A ++ +G G + P PP+ + S S G A + +
Sbjct: 754 HAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHG 813
Query: 1115 LSTPRPTRASRLRR------------ARLGDASDTEAADGERG--SLGNPEPVGRPAAEQ 1160
+P A L R + + + ++G +G P P A++
Sbjct: 814 QGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQE 873
Query: 1161 AKKLSRLDILAMPRKRAGSFTG--------TSDPEAAPARTSFSGRSVELCCASRKPTMA 1212
A + R GSF G +S P + P S S + + S P M
Sbjct: 874 AAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMV 933
Query: 1213 EARAVSRKAANTATTTGPRQPFSRARSGSARYTSTTQTPRAGS-SSRARSRAPGP 1266
+ A S A+ + + P G T ++ S SS+ S+ P P
Sbjct: 934 NSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKDSYSSQGISQPPTP 988
Score = 33.5 bits (75), Expect = 1.6
Identities = 55/258 (21%), Positives = 94/258 (36%), Gaps = 44/258 (17%)
Query: 691 GSLPVRMRRRLPQLPSERADSPAGPESSRRSGPGPP-------ELDSEQPSRLFGQEELD 743
G+ +M + PQ R + +G S+ SGPGP ++ + PS+ G L
Sbjct: 767 GTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLG 826
Query: 744 ------------PDSLSDASGSDGGRGPE--PGV-EPQDSRRRSPQEGPTWSRGRRSPRA 788
P ++S + S G + PG+ P + R QE + A
Sbjct: 827 RMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEA---AAAVMQAAA 883
Query: 789 PGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSANGRMV--- 845
+ F G + S P + P + Q P + V+++ V
Sbjct: 884 NSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLA 943
Query: 846 IQLRPGRSPEP-----DG-----PAPAFLRQESFTKEPASGPPAPGKPPHISSHPLLQDL 895
+ PG S P DG P P ++S++ + S PP PG + P+ +
Sbjct: 944 DMMSPGESKLPLPLKADGKEEGTPQPESKSKDSYSSQGISQPPTPG------NLPVPSPM 997
Query: 896 AATRAARMDFHSQDTHLI 913
+ + A+ FH ++ I
Sbjct: 998 SPSSASISSFHGDESDSI 1015
Score = 33.5 bits (75), Expect = 1.6
Identities = 48/212 (22%), Positives = 79/212 (37%), Gaps = 15/212 (7%)
Query: 686 GGEPEGSLPVRMRRRLPQLPSERADSPAGPESSRRSGPGP----PELDSEQPSRLFGQEE 741
G P G +P + P + + +P+ P S++ GPG P ++ + +
Sbjct: 821 GAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQ 880
Query: 742 LDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQEGPTWSRGRRSPRAPGEP-----TPAS 796
+S GS G + G+ S P + ++P P + AS
Sbjct: 881 AAANSAQSRQGSFPGMN-QSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAAS 939
Query: 797 FFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSANGRMVIQLRPGRSPEP 856
+ D S+ PL DG+ G T QP ++D S+ G + PG P P
Sbjct: 940 VGLADMMSPGE-SKLPLPLKADGKEEG-TPQPESKSKDSY--SSQG-ISQPPTPGNLPVP 994
Query: 857 DGPAPAFLRQESFTKEPASGPPAPGKPPHISS 888
+P+ SF + + +PG P SS
Sbjct: 995 SPMSPSSASISSFHGDESDSISSPGWPKTPSS 1026
>gi|18079216 CASK interacting protein 1 [Homo sapiens]
Length = 1431
Score = 56.6 bits (135), Expect = 2e-07
Identities = 186/779 (23%), Positives = 255/779 (32%), Gaps = 133/779 (17%)
Query: 540 PPTPPPAPTDPQLTKARKQEEDDSLSDAGTYTIETEAQDTEVEEARKMIDQVFGVLESPE 599
PP P P P D Q K + D LSD E +A T E ++ L P
Sbjct: 634 PPPPEPTPADCQSPKMTTFQ-DSELSD------ELQAAMTGPAEVGPTTEKPSSHL--PP 684
Query: 600 LSRASSATFRPVIRGDRDESDDGGVAQRMALLQEFASR--PLGAAPQAEHQGL-----PV 652
RA++ R +S GG A+ M+ QE P ++P + Q P
Sbjct: 685 TPRATT----------RQDSSLGGRARHMSSSQELLGDGPPGPSSPMSRSQEYLLDEGPA 734
Query: 653 PGSPGGQKWVSRWASLADSYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERADSP 712
PG+P + + PG + R P +P + R+ LP P +P
Sbjct: 735 PGTPPRE-------------ARPGRHGHSIKRASVPP---VPGKPRQVLP--PGTSHFTP 776
Query: 713 AGPESSRRSGPGPPEL--DSEQPSRLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSRR 770
P++ ++ PG P+ P+ + + P L R P PQ
Sbjct: 777 --PQTPTKTRPGSPQALGGPHGPAPATAKVKPTPQLLPPTE-----RPMSPRSLPQSPTH 829
Query: 771 RS-PQEGPTWSRGRRSPRAPGE-----PTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQ 824
R P G P APG PT DA R A
Sbjct: 830 RGFAYVLPQPVEGEVGPAAPGPAPPPVPTAVPTLCLPPEADAEPGRPKKRAHSLNR---Y 886
Query: 825 TAQPSPPARDGVYV--SANGRMVIQLRPGRSPEPDGPAPA---FLRQESFTKEPAS-GPP 878
A S P RD + V +A +Q R GRS PA A R +SF P GPP
Sbjct: 887 AASDSEPERDELLVPAAAGPYATVQRRVGRSHSVRAPAGADKNVNRSQSFAVRPRKKGPP 946
Query: 879 APGKPPHISSHPLLQDLAATRAARMDFHSQDTHLILKETETALAALEARL-----LSNSV 933
P PP SS L A D + E E L + A+ L+ SV
Sbjct: 947 PP--PPKRSSSALASANLA-----------DEPVPDAEPEDGLLGVRAQCRRASDLAGSV 993
Query: 934 DAECEGGSTPRPPEDALSGDSDVDTASTVSLR--SGKSGPSPTTPQPLRAQKEM-SPSPP 990
D G A+ S + + R G P P +P+P R + S
Sbjct: 994 DTGSAGSVKSIA---AMLELSSIGGGGRAARRPPEGHPTPRPASPEPGRVATVLASVKHK 1050
Query: 991 AAQDPGGTALVSAREQSSERQHHPLGPTDMGRGE-----PVRRSAIRRGHRPRGSLDWPS 1045
A PGG +V+ R S L G GE P R RPRG +
Sbjct: 1051 EAIGPGGE-VVNRRRTLSGPVTGLLATARRGPGESADPGPFVEDGTGR-QRPRGPSKGEA 1108
Query: 1046 EERGPVLAHLPSSDVMA------SNHE-------TPEATGAGRLGSRRKPAAPPPSPAAR 1092
GP LA + +S + N + T T R ++ + A P P P
Sbjct: 1109 GVEGPPLAKVEASATLKRRIRAKQNQQENVKFILTESDTVKRRPKAKEREAGPEPPPPLS 1168
Query: 1093 EEQS------RSSASSQKGPQALTRSNSLSTPRPTRASRLRRARLGDASDTEAADGERGS 1146
+ R AS Q GP L + P PT + L +GE
Sbjct: 1169 VYHNGTGTVRRRPASEQAGPPELPPPPPPAEPPPTDLAHL--------PPLPPPEGEARK 1220
Query: 1147 LGNPEPVGRPAAEQAKKLSRLDILAMPRKRAGSFTGTSDPEAAPARTSFSGRSVELCCAS 1206
P +P Q + +L P + G PE A + S +
Sbjct: 1221 PAKPPVSPKPVLTQP--VPKLQGSPTPTSKKVPLPGPGSPEVKRAHGTPPPVSPK----- 1273
Query: 1207 RKPTMAEARAVSRKAANTATTTGPRQPFSRARSGSARYTSTTQTPRAGSSSRARSRAPG 1265
P + V A + + GP S AR A TP + +S A+ +PG
Sbjct: 1274 PPPPPTAPKPVKAVAGLPSGSAGPSPAPSPARQPPAALAKPPGTPPSLGASPAKPPSPG 1332
Score = 56.6 bits (135), Expect = 2e-07
Identities = 103/417 (24%), Positives = 143/417 (34%), Gaps = 82/417 (19%)
Query: 190 PYPERPKGPVQQD-GELHGFRAPAEPQGCSFRREPSYFEIPTKETPQPSQPPEVPAH--- 245
P P VQ+ G H RAPA + R S+ P K+ P P P +
Sbjct: 901 PAAAGPYATVQRRVGRSHSVRAPAGADK-NVNRSQSFAVRPRKKGPPPPPPKRSSSALAS 959
Query: 246 ----EMPTKDAEAGGG--GAAPVVQSHASFTIEFDDCSPGKMKIKDHITKFSL------R 293
+ P DAE G G + + D S G +K + + S
Sbjct: 960 ANLADEPVPDAEPEDGLLGVRAQCRRASDLAGSVDTGSAGSVKSIAAMLELSSIGGGGRA 1019
Query: 294 QRRPPGKEATPGEMVSAETKVADWLVQNDPSLLHR--VGPGDDRHSTKSDLPVHTRTL-- 349
RRPP TP +VA L S+ H+ +GPG + + + L L
Sbjct: 1020 ARRPPEGHPTPRPASPEPGRVATVLA----SVKHKEAIGPGGEVVNRRRTLSGPVTGLLA 1075
Query: 350 -----------KGHKHEDGT-QSDSEDPLAKAASAAGVPLEASGEQVRLQRQIKRDPQEL 397
G EDGT + P A G PL L+R+I+
Sbjct: 1076 TARRGPGESADPGPFVEDGTGRQRPRGPSKGEAGVEGPPLAKVEASATLKRRIRAK---- 1131
Query: 398 LHNQQAFVIEFFDEDTPRKKRSQSFTHSPSGDPKADKRR-GPTPADRDRPSVPAPVQAGG 456
NQQ V E K+R PKA +R GP P P P+
Sbjct: 1132 -QNQQENVKFILTESDTVKRR-----------PKAKEREAGPEP--------PPPLSVYH 1171
Query: 457 RSSGPQRAGSLKREKTEERLGSPSPASRTPAR----------PFGSVGRRSR---LAQDF 503
+G R + L P P + P P G + ++ +
Sbjct: 1172 NGTGTVRRRPASEQAGPPELPPPPPPAEPPPTDLAHLPPLPPPEGEARKPAKPPVSPKPV 1231
Query: 504 MAQCLRESSPAARPSPEKVPPVLPAPLTP-----HGTSPVGPPTPPPAPTDPQLTKA 555
+ Q + + + P+ +KVP LP P +P HGT P P PPP PT P+ KA
Sbjct: 1232 LTQPVPKLQGSPTPTSKKVP--LPGPGSPEVKRAHGTPPPVSPKPPPPPTAPKPVKA 1286
Score = 46.2 bits (108), Expect = 2e-04
Identities = 185/853 (21%), Positives = 261/853 (30%), Gaps = 194/853 (22%)
Query: 229 PTKETPQPSQPPEVPAHEMPTKDAEAGGGGAAPVVQSHASFTIEFDDCSPGKMKIKDHIT 288
PT E P PP A T ++ GG A + S D PG
Sbjct: 673 PTTEKPSSHLPPTPRA----TTRQDSSLGGRARHMSSSQEL---LGDGPPGPSSPMSRSQ 725
Query: 289 KFSLRQRRPPG---KEATPGEMVSAETKVADWLVQNDPSLLHRVGPGDDRHSTKSDLPVH 345
++ L + PG +EA PG + + + V P +V P H T P
Sbjct: 726 EYLLDEGPAPGTPPREARPGRHGHSIKRAS---VPPVPGKPRQVLPPGTSHFTPPQTPTK 782
Query: 346 TRTLKGHKHEDGTQSDSEDPLAKAASAAGVP----LEASGEQVRLQRQIKRDPQELLHNQ 401
TR G+ P A + A V L E+ R + PQ H
Sbjct: 783 TRP--------GSPQALGGPHGPAPATAKVKPTPQLLPPTERPMSPRSL---PQSPTHRG 831
Query: 402 QAFVIEFFDEDTPRKKRSQSFTHSPSGDPKADKRRGPTPADRDRPSVPAPVQAGGRSSGP 461
A+V+ P+ + +P P P P++ P +A P
Sbjct: 832 FAYVL-------PQPVEGEVGPAAPGP--------APPPVPTAVPTLCLPPEADAEPGRP 876
Query: 462 Q-RAGSLKR----EKTEERLGSPSPASRTPARPFGSVGRRSRLAQDFMAQC------LRE 510
+ RA SL R + ER PA+ A P+ +V RR + A R
Sbjct: 877 KKRAHSLNRYAASDSEPERDELLVPAA---AGPYATVQRRVGRSHSVRAPAGADKNVNRS 933
Query: 511 SSPAARPSPEKVPPVLPAPLTPHGTSPVGPPTPPPAPTDPQLTKARKQEEDDSLSDAGTY 570
S A RP + GPP PPP + L A +E ++
Sbjct: 934 QSFAVRPRKK------------------GPPPPPPKRSSSALASANLADEPVPDAEPEDG 975
Query: 571 TIETEAQDTEVEEARKMID--------QVFGVLESPELSRASSATFRPVIRGDRDES--- 619
+ AQ + +D + +LE + A RP
Sbjct: 976 LLGVRAQCRRASDLAGSVDTGSAGSVKSIAAMLELSSIGGGGRAARRPPEGHPTPRPASP 1035
Query: 620 DDGGVAQRMALLQEFASRPLGAAPQAEHQGLPVPGSPGGQKWVSRWASLADSYSDPG-LT 678
+ G VA +A ++ +G + ++ + G G +R +DPG
Sbjct: 1036 EPGRVATVLASVKH--KEAIGPGGEVVNRRRTLSGPVTGLLATARRGP--GESADPGPFV 1091
Query: 679 EDGLGR---RG---------GEP----EGSLPVRMRRRLPQLPSERAD-----------S 711
EDG GR RG G P E S ++ R R Q E
Sbjct: 1092 EDGTGRQRPRGPSKGEAGVEGPPLAKVEASATLKRRIRAKQNQQENVKFILTESDTVKRR 1151
Query: 712 PAGPESSRRSGPGPPE-----------LDSEQPSRLFGQEELDPDSLSDASGSDGGRGPE 760
P E R +GP PP + S G EL P A
Sbjct: 1152 PKAKE--REAGPEPPPPLSVYHNGTGTVRRRPASEQAGPPELPPPP-PPAEPPPTDLAHL 1208
Query: 761 PGVEPQDSRRRSPQEGPTWSRG---RRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPG 817
P + P + R P + P + + P+ G PTP S + PL PG
Sbjct: 1209 PPLPPPEGEARKPAKPPVSPKPVLTQPVPKLQGSPTPTS------------KKVPLPGPG 1256
Query: 818 DGE-----GLGQTAQPSPPARDGVYVSANGRMVIQLRPGRSPEPDGPAPAFLRQESFTKE 872
E G P PP ++ G GP+PA
Sbjct: 1257 SPEVKRAHGTPPPVSPKPPP------PPTAPKPVKAVAGLPSGSAGPSPA--------PS 1302
Query: 873 PASGPPA-----PGKPPHISSHPLLQDLAATRAARMDFHSQDTHLILKETETALAALEAR 927
PA PPA PG PP + + P A H+ K A AA A
Sbjct: 1303 PARQPPAALAKPPGTPPSLGASPAKPPSPGAPAL---------HVPAKPPRAAAAAAAA- 1352
Query: 928 LLSNSVDAECEGGSTPRPPEDALSGDSDVDTASTVSLRSGKSGPSPTTPQPLRAQKEMSP 987
+ P PPE A GDS S + + + +R + P
Sbjct: 1353 -----------AAAPPAPPEGASPGDSARQKLEETS--ACLAAALQAVEEKIRQEDAQGP 1399
Query: 988 SPPAAQDPGGTAL 1000
AA+ G+ L
Sbjct: 1400 RDSAAEKSTGSIL 1412
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
Length = 816
Score = 56.6 bits (135), Expect = 2e-07
Identities = 172/761 (22%), Positives = 252/761 (33%), Gaps = 97/761 (12%)
Query: 477 GSPSPASR-TPAR-----PFGSVGRR--SRLAQDFMAQCLRESSPAARPSPEKVPPVLPA 528
GSP P TPA G+VGR+ + A + ES+P A P+ PP
Sbjct: 31 GSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRPPA--- 87
Query: 529 PLTPHGTSPVGPPTPPPAPTDP-QLTKARKQEEDDSLSDAGTYTIETEAQDTEVEEARKM 587
S G PP T P ++ + G + A++T
Sbjct: 88 -------SGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGK--- 137
Query: 588 IDQVFGVLESPELSRASSATFRPVIRGDRDESDDGGVAQRMALLQEFASRPLGAAPQAEH 647
E+P+ S S+ R D G + MA A +G P+
Sbjct: 138 ------ATEAPKRSALSAGA-----RRDTSGPTPGTPSPAMARRSRAAGTEVGL-PRPAP 185
Query: 648 QGLPVPGSPGGQKWVSRWASLADSYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSE 707
P P + G +K VS S S+ TE R G R R +
Sbjct: 186 SARPRPPTEGPRKSVS-------SASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT 238
Query: 708 RADSPAGPESSRRSGPGPPELDSEQPSRLFGQEELDPDSLS----DASGSDGGRGPEPGV 763
SPA S R P P S+ + G + L P ++ DA+ + G P
Sbjct: 239 PLSSPARSGPSARGTPRAPAHPSQPKPK--GLQALRPPQVTPPRKDAAPALGPLSSSPLA 296
Query: 764 EPQDSRRRSPQEGPTWSRGRRSPRAPGEPTPASFFIGDQNGDAVLS------RKPLAAPG 817
P S SP P+ P P P+ A+ +G A S PLA P
Sbjct: 297 TPSPSAPPSPSAPPSLQTLPSPPATP--PSQATTSLGSPTLQATHSFLPSPPLSPLATPP 354
Query: 818 DGEGLGQT-----AQPSPPARDGVYVSA-------NGRMVIQLRPGRSPEPDGPAPA-FL 864
A PSPPA + A N V L+ SP P P A F
Sbjct: 355 PQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFS 414
Query: 865 RQESFTKEPASGPPAPGKPPHISSHPLLQDLAATRAARMDFHSQDTHLILKETETALAAL 924
S P++ PP+ PP +++ PL + + M + + LAA
Sbjct: 415 PPASPPVSPSATPPSQA-PPSLAAPPLQVPPSPPASPPMSPSATPP----PQAPPPLAAP 469
Query: 925 EARLLSNSVDAECEGGSTPRP----PEDALSGDSDVDTASTVSLRSGKSGPSPTTPQPLR 980
+L A + P P + G + ++++ + S + P P P L
Sbjct: 470 PLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPM-SPLATPPPQAPPVLA 528
Query: 981 AQK-EMSPSPPAAQD---------PGGTALVSAREQSSERQHHP-----LGPTDMGRGEP 1025
A ++ PSPPA+ PG VS + P P+ G
Sbjct: 529 APLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPD 588
Query: 1026 VRRSAIRRGHRPRGSLDWPSEERGPVLAHLPSSDVMASNHETPEATG-AGRLGSRRKPAA 1084
+ + P + S G A P +A+ H + G A L R P A
Sbjct: 589 LAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGA 648
Query: 1085 PPPSPAAREEQSRSSASS---QKGPQALTRSNSLSTPRPTRASRLRRARLGDASDTEAAD 1141
P P P A S + +GP++ T + P P+ + +A G + +
Sbjct: 649 PLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRS 708
Query: 1142 GERGSLGNPEPVGRPAAEQAKKLSRLDILAMPRKRAGSFTG 1182
++ LG A+ LSR +LA AG G
Sbjct: 709 PKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGG 749
Score = 51.2 bits (121), Expect = 8e-06
Identities = 113/503 (22%), Positives = 155/503 (30%), Gaps = 96/503 (19%)
Query: 414 PRKKRSQSFTHSPSGDPKADKRRGPT-------PADRDRPSVPAPVQAGGRSSGPQRAGS 466
PRK S + HS + +P RR P+ PA R S P+ + R SGP G+
Sbjct: 196 PRKSVSSASEHSTT-EPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPAR-SGPSARGT 253
Query: 467 LKREKTEERLGSPSPASRTPARPFGSVGRRSRLAQ---DFMAQCLRESSPAARPSPEKVP 523
+ P P RP R A + L SP+A PSP P
Sbjct: 254 ---PRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310
Query: 524 PV--LPA-PLTP--HGTSPVGPPT-----------------PPPAPTDPQLTKARKQEED 561
+ LP+ P TP T+ +G PT PP P L Q
Sbjct: 311 SLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPP 370
Query: 562 DSLSDAGTYTIETEAQDTEVEEARKMIDQVFGVLESPELSRASSATFRPVIRGDRDESDD 621
+ + T + A ++ F SP + S P +
Sbjct: 371 SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQ 430
Query: 622 GGVAQRMALLQEFASRPLGAAPQAEHQGLPVPGSPGGQKWVSRWASLADSYSDPGLTEDG 681
+ LQ S P A+P P P +P + + P L
Sbjct: 431 APPSLAAPPLQVPPSPP--ASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPP 488
Query: 682 L-----------GRRGGEPEGSLPVR------------MRRRLPQLPSERADSP------ 712
L G+ P SLP+ + L Q+P SP
Sbjct: 489 LQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPR 548
Query: 713 -----------AGPESSRRSGPGPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPEP 761
+GP + PGPP S PS +L S S S + RG +
Sbjct: 549 RPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDS 608
Query: 762 GVE------PQDSRRRSPQEGPTWSRGRRSP----RAPGEPTPASFFIGDQNGDAVLSRK 811
G E P + WSRG P APG P P G + D + +
Sbjct: 609 GPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIY 668
Query: 812 PLAAPGDGEGLGQTAQPSPPARD 834
P ++A P+P A D
Sbjct: 669 ETEGP-------ESATPAPGALD 684
Score = 48.1 bits (113), Expect = 6e-05
Identities = 89/347 (25%), Positives = 124/347 (35%), Gaps = 66/347 (19%)
Query: 1067 TPEATGAGRL-----GSRRKPAAPPPSPAAREEQSRSSASSQKG-------------PQA 1108
TP A G L GS R P PP +PAA + A +K P++
Sbjct: 16 TPAARAPGLLTPRPPGSPRPP--PPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPES 73
Query: 1109 LTRSNSLSTPRPTRASRLRRA------RLGDASDTEAADGER--GSLGNP-------EPV 1153
R+ T RP + R RA G S A G G LG E V
Sbjct: 74 APRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETV 133
Query: 1154 GRPAAEQAKKLSRLDILAMPRKRAGSFTGTSDPEAAPARTSFSGRSVEL-----CCASRK 1208
R A +A K S L A R +G GT P A R+ +G V L R
Sbjct: 134 ARGKATEAPKRSALSAGAR-RDTSGPTPGTPSPAMA-RRSRAAGTEVGLPRPAPSARPRP 191
Query: 1209 PTMAEARAVSRKAANTATTTGP------------RQPFSRARSGSARYTSTTQTPRAGSS 1256
PT ++VS + ++ T P ++P SR+ S SA T + R+G S
Sbjct: 192 PTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSA--TPLSSPARSGPS 249
Query: 1257 SRARSRAPGPRDTDDDEEEPDPYGFIVQTAEIAEIARLSQTLVKDVAILAQEIHDVAGDG 1316
+R RAP +P P G +Q ++ + + L+
Sbjct: 250 ARGTPRAPA------HPSQPKPKG--LQALRPPQVTPPRKDAAPALGPLSSSPLATPSPS 301
Query: 1317 DTLGSSEPAHSASLSNMPSTPASTISAREELVQRIPEASLNFQKVPP 1363
S P +L + P+TP S A L +A+ +F PP
Sbjct: 302 APPSPSAPPSLQTLPSPPATPPS--QATTSLGSPTLQATHSFLPSPP 346
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 56.6 bits (135), Expect = 2e-07
Identities = 97/462 (20%), Positives = 141/462 (30%), Gaps = 101/462 (21%)
Query: 424 HSPSGDPKAD-KRRGPTPADRDRPSVPAPVQAGGRSSGPQRAGSLKREKTEERLGSPSPA 482
+ P G P K +GP P ++P P P G+ GP G K + G P P
Sbjct: 45 NKPQGPPSPPGKPQGPPPQGGNQPQGPPPPP--GKPQGPPPQGGNKPQ------GPPPPG 96
Query: 483 SRTPARPFGSVGRRSRLAQDFMAQCLRESSPAARPSPEKVPPVLPAPLTPHGTSPVGPPT 542
P G R R SP +P P G P GPP
Sbjct: 97 KPQGPPPQGDKSRSPR-------------SPPGKPQ---------GPPPQGGNQPQGPPP 134
Query: 543 PPPAPTDPQLTKARKQEEDDSLSDAGTYTIETEAQDTEVEEARKMIDQVFGVLESPELSR 602
PP P P K + + + + + + G + P
Sbjct: 135 PPGKPQGPPPQGGNKPQGPPPPG-------KPQGPPPQGDNKSRSSRSPPGKPQGP---- 183
Query: 603 ASSATFRPVIRGDRDESDDGGVAQRMALLQEFASRPLGAAPQAEHQGLPVPGSPGGQKWV 662
P G++ + + + ++P G P + QG P G Q
Sbjct: 184 -------PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQ--- 233
Query: 663 SRWASLADSYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERADSPAGPESSRRSG 722
+ S PG + + G +P+G P + + P P + + P GP +
Sbjct: 234 -------SARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP--PPQGGNKPQGPPPPGKPQ 284
Query: 723 PGPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQEGPTWSRG 782
PP+ S+ S P GG P+ P + P +G +G
Sbjct: 285 GPPPQGGSKSRS------SRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQG 338
Query: 783 RRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSANG 842
P P P P Q G SR + PG +G PP ++G
Sbjct: 339 PPPPGKPQGPPP-------QGGSK--SRSARSPPGKPQG--------PPQQEG------- 374
Query: 843 RMVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPP 884
P P P G P + PA P P +PP
Sbjct: 375 -----NNPQGPPPPAGGNP-----QQPQAPPAGQPQGPPRPP 406
Score = 53.5 bits (127), Expect = 2e-06
Identities = 65/270 (24%), Positives = 89/270 (32%), Gaps = 35/270 (12%)
Query: 637 RPLGAAPQAEH--QGLPVPGSPGGQKWVSRWASLADSYSDPGLTEDGLGRRGGEPEGSLP 694
+P G PQ + QG P PG P G S + S S PG + + G +P+G P
Sbjct: 138 KPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRS-SRSPPGKPQGPPPQGGNQPQGPPP 196
Query: 695 VRMRRRLPQLPSERADSPAGPESSRRSGPGPPELDSEQPSRLFGQEELDPDSLSDASGSD 754
+ + P P + + P GP + PP+ D++ Q P
Sbjct: 197 PPGKPQGP--PPQGGNKPQGPPPPGKPQGPPPQGDNKS------QSARSPPGKPQGPPPQ 248
Query: 755 GGRGPEPGVEPQDSRRRSPQEGPTWSRGRRSPRAPGEPTPASFFIGDQNGDAVLSR---- 810
GG P+ P + P +G +G P P P P Q G S
Sbjct: 249 GGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPP-------QGGSKSRSSRSPP 301
Query: 811 -KPLAAPGDGEGLGQTAQPSPPARDGVYVSANGRMVIQLRPGRSPEPDGPAPAFLRQESF 869
KP P G Q P P G + PG+ P GP P +
Sbjct: 302 GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK---PQGPPPQGGSKSRS 358
Query: 870 TKEPASGPPAP---------GKPPHISSHP 890
+ P P P G PP +P
Sbjct: 359 ARSPPGKPQGPPQQEGNNPQGPPPPAGGNP 388
Score = 52.0 bits (123), Expect = 4e-06
Identities = 71/267 (26%), Positives = 94/267 (35%), Gaps = 54/267 (20%)
Query: 635 ASRPLGAAPQAEH--QGLPVP-GSPGGQKWVSRWASLADSYSDPGLTEDGLGRRGG---- 687
A P GA PQ + QG P P G P G + + P G +GG
Sbjct: 33 AGNPQGAPPQGGNKPQGPPSPPGKPQGPP--PQGGNQPQGPPPPPGKPQGPPPQGGNKPQ 90
Query: 688 ------EPEGSLPVRMRRRLPQLPSERADSPAGPESSRRSGPGPPELDSEQPSRLFGQEE 741
+P+G P + R P+ P + P ++ GP PP + P
Sbjct: 91 GPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP-------- 142
Query: 742 LDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQEGPTWSRGRRSPRAPGEPTPASFFIGD 801
G + +GP P +PQ P +G SR RSP PG+P G+
Sbjct: 143 -------PPQGGNKPQGPPPPGKPQG----PPPQGDNKSRSSRSP--PGKPQGPPPQGGN 189
Query: 802 Q-NGDAVLSRKPLAAPGDG----EGLGQTAQPSPPARDGVYVSANGRMVIQLRPGRSPEP 856
Q G KP P G +G +P P G S + R PG+ P
Sbjct: 190 QPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARS----PPGK---P 242
Query: 857 DGPAPAFLRQESFTKEPASGPPAPGKP 883
GP P +P PP PGKP
Sbjct: 243 QGPPP------QGGNQPQGPPPPPGKP 263
Score = 51.2 bits (121), Expect = 8e-06
Identities = 98/432 (22%), Positives = 129/432 (29%), Gaps = 104/432 (24%)
Query: 705 PSERADSPAGPESSRRSGPGPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPEPGVE 764
P + + P GP S GPP QP Q P GG P+ G
Sbjct: 40 PPQGGNKPQGPPSPPGKPQGPPPQGGNQP-----QGPPPPPGKPQGPPPQGGNKPQ-GPP 93
Query: 765 PQDSRRRSPQEGPTWSRGRRSPRAPGEPTPASFFIGDQ-NGDAVLSRKPLAAPGDGEGLG 823
P + P +G SR RSP PG+P G+Q G KP P G
Sbjct: 94 PPGKPQGPPPQGDK-SRSPRSP--PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP 150
Query: 824 QTAQPSPPAR-DGVYVSANGRMVIQLRPGRSP--EPDGPAPAFLRQESFTKEPASGPPAP 880
Q P PP + G + + R RSP +P GP P Q P P P
Sbjct: 151 QG--PPPPGKPQGPPPQGDNKS----RSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP 204
Query: 881 GKPPHISSHPLLQDLAATRAARMDFHSQDTHLILKETETALAALEARLLSNSVDAECEGG 940
PP +GG
Sbjct: 205 --PP-----------------------------------------------------QGG 209
Query: 941 STPR--PPEDALSGDSDVDTASTVSLRSGKSGPSPTTPQPLRAQKEMSPSPPAAQDPGGT 998
+ P+ PP G + S RS P P P + P PP + G
Sbjct: 210 NKPQGPPPPGKPQGPPPQGDNKSQSARSPPG--KPQGPPPQGGNQPQGPPPPPGKPQGPP 267
Query: 999 ALVSAREQSSERQHHPLGPTDMGRGEPVRRSAI----------RRGHRPRGSLDWPSEER 1048
+ Q P GP G G R S + G++P+G P + +
Sbjct: 268 PQGGNKPQGPPPPGKPQGPPPQG-GSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 326
Query: 1049 GPVLAHLPSSDVMASNHETPEATGAGRLGSRRKPAAPPPSPAAREEQSRSSASSQKGPQA 1108
GP P + + P G KP PPP ++ +RS +GP
Sbjct: 327 GPP----PQG---GNKPQGPPPPG--------KPQGPPPQGGSKSRSARSPPGKPQGPPQ 371
Query: 1109 LTRSNSLSTPRP 1120
+N P P
Sbjct: 372 QEGNNPQGPPPP 383
Score = 47.8 bits (112), Expect = 8e-05
Identities = 89/382 (23%), Positives = 121/382 (31%), Gaps = 75/382 (19%)
Query: 414 PRKKRSQSFTHSPSGDPKADKRRGPTPADRDRPSVPAPVQAGGRSSGPQRAGSLKREKTE 473
P+ +S+S SP G P+ GP P ++P P P G+ GP G K +
Sbjct: 103 PQGDKSRS-PRSPPGKPQ-----GPPPQGGNQPQGPPPPP--GKPQGPPPQGGNKPQ--- 151
Query: 474 ERLGSPSPASRTPARPFGSVGRRSRLAQDFMAQCLRESSPAARPSPEKVPPVLPAPLTPH 533
G P P P G RS SP +P P
Sbjct: 152 ---GPPPPGKPQGPPPQGDNKSRS------------SRSPPGKPQ---------GPPPQG 187
Query: 534 GTSPVGPPTPPPAPTDPQLTKARKQEEDDSLSDAGTYTIETEAQDTEVEEARKMIDQVFG 593
G P GPP PP P P K + G D + + AR G
Sbjct: 188 GNQPQGPPPPPGKPQGPPPQGGNKPQ---GPPPPGKPQGPPPQGDNKSQSARSPP----G 240
Query: 594 VLESPELSRASSATFRPVIRGDRDESDDGGVAQRMALLQEFASRPLGAAPQA--EHQGLP 651
+ P + P G +P G PQ + QG P
Sbjct: 241 KPQGPPPQGGNQPQGPPPPPG----------------------KPQGPPPQGGNKPQGPP 278
Query: 652 VPGSPGGQKWVSRWASLADSYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERADS 711
PG P G + S S PG + + G +P+G P + + P P + +
Sbjct: 279 PPGKPQGPP-PQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP--PPQGGNK 335
Query: 712 PAGPESSRRSGPGPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPEPG----VEPQD 767
P GP + PP+ S+ SR P G++ P P +PQ
Sbjct: 336 PQGPPPPGKPQGPPPQGGSK--SRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQA 393
Query: 768 SRRRSPQEGPTWSRGRRSPRAP 789
PQ P +G R R P
Sbjct: 394 PPAGQPQGPPRPPQGGRPSRPP 415
Score = 31.6 bits (70), Expect = 6.2
Identities = 30/121 (24%), Positives = 42/121 (34%), Gaps = 16/121 (13%)
Query: 136 EHTPYCEASNPR--PEKGDRRPGTEAASYRTPLYGQPSWWGEDDGSTLPDAQRQGEPY-- 191
E +P A NP+ P +G +P + P P + G P + QG P
Sbjct: 26 EESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG 85
Query: 192 ---------PERPKGPVQQDGELHGFRAPAEPQGCSFRREPSYFEIPTKETPQPSQPPEV 242
P +P+GP Q + R+P P G P P P P +P
Sbjct: 86 GNKPQGPPPPGKPQGPPPQGDK---SRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP 142
Query: 243 P 243
P
Sbjct: 143 P 143
>gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 [Homo
sapiens]
Length = 2178
Score = 55.8 bits (133), Expect = 3e-07
Identities = 146/705 (20%), Positives = 227/705 (32%), Gaps = 125/705 (17%)
Query: 641 AAPQAEHQGLPVPGSPGGQKWVSRWASLADSYSDPGLTEDGLGRRGGE---PEGSLPVRM 697
++P+ + G+ + GG +S+ A+ G G R G+ P G+ P
Sbjct: 311 SSPRQQGGGMMMGPGGGGAASLSKAAA--------GSAAGGFQRFAGQNQHPSGATPTLN 362
Query: 698 RRRLPQLPSERADSPAGPESSRRSGPGPPELDSEQPSRLFG------QEELDPDSLSDAS 751
+ P R+ + PE S S P PP + + G Q D
Sbjct: 363 QLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMG 422
Query: 752 GSDGGRGPEPGVEPQDSR-RRSP-QEGPTWSRGRRSPRAP----------------GEPT 793
P Q S SP GPT R + SP P +P
Sbjct: 423 AQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQ 482
Query: 794 PASFFIGDQNGDAVLSRKPLA----APGDGEGLGQTAQPSPPARDGVYVSANGRMVIQLR 849
+S + G G R P+ PG G+ Q PP VS + Q
Sbjct: 483 QSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPY 542
Query: 850 PGRSPEPDGPAP-----------AFLRQESFTKE---PASGPP-APGKPPHISSHPLLQD 894
+ P+P P + Q+ ++E S PP APGKP H
Sbjct: 543 YSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNH--------- 593
Query: 895 LAATRAARMDFHSQDTHLILKETETALAALEARL----------LSNSVDAECEGGSTPR 944
+D +LI +E ++L L + LS++V A GST
Sbjct: 594 -------------EDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSA---SGSTSS 637
Query: 945 PPEDALSGDSDVDTASTVSLRSGKSGPSPT-TPQPLRAQKEMSPSPPAAQDPGGTALVSA 1003
+ + S ++ L S GPSP+ P+ + + S A PG
Sbjct: 638 QGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQP 697
Query: 1004 REQSSERQHHP-LGPTDMGRGEPVRRSAIRRGHRPRGSLDWPSEERGPVLAHLPS--SDV 1060
SE HP L + M P R + R + ++ GP ++ PS +
Sbjct: 698 PGSQSESSSHPALSQSPM----PQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQM 753
Query: 1061 MASNHETPEATGAGRLGSRRKPAAP------PPSPAAREEQSRSSASSQKGPQALTRSNS 1114
A ++ +G G + P PP+ + S S G A + +
Sbjct: 754 HAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHG 813
Query: 1115 LSTPRPTRASRLRR------------ARLGDASDTEAADGERG--SLGNPEPVGRPAAEQ 1160
+P A L R + + + ++G +G P P A++
Sbjct: 814 QGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQE 873
Query: 1161 AKKLSRLDILAMPRKRAGSFTG--------TSDPEAAPARTSFSGRSVELCCASRKPTMA 1212
A + R GSF G +S P + P S S + + S P M
Sbjct: 874 AAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMV 933
Query: 1213 EARAVSRKAANTATTTGPRQPFSRARSGSARYTSTTQTPRAGSSS 1257
+ A S A+ + + P G T ++ SSS
Sbjct: 934 NSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKKSSS 978
>gi|178557734 microtubule-associated protein tau isoform 6 [Homo
sapiens]
Length = 776
Score = 55.5 bits (132), Expect = 4e-07
Identities = 130/548 (23%), Positives = 197/548 (35%), Gaps = 112/548 (20%)
Query: 641 AAPQAEHQGLPV--PGSPGGQKWVSRWASLADSYS--------DPGLTEDGLGRRGGEPE 690
+ P AE P+ G+PG Q + + + P L ++ G EPE
Sbjct: 68 STPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQEPE 127
Query: 691 GSLPVR---MRRRLP-----QLPSERADSPAGPESSRR-----SGPGPPELDSEQPS--- 734
V+ +R P QL S +P PE R SG GP + + + +
Sbjct: 128 SGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEGGRHAPEL 187
Query: 735 ---RLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQEGPT------------W 779
+L G + L A G + E E +D SPQ+ P
Sbjct: 188 LKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQ 247
Query: 780 SRGRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVS 839
+ R + PG P + + V + P + P DG +G+ P +V
Sbjct: 248 TAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEP-DGPSVGRAKGQDAPLEFTFHVE 306
Query: 840 AN--------------GRMVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGPPAP---GK 882
GR PG PE GP+ +E+ EP+ PA GK
Sbjct: 307 ITPNVQKEQAHSEEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGK 366
Query: 883 PPHISSHPLLQDLAATRAARMDFHSQD-THLILKETETALAALEARLLSN----SVDAEC 937
P +S P L+ ARM S+D T K+ +T+ + A+ L N S
Sbjct: 367 P--VSRVPQLK-------ARMVSKSKDGTGSDDKKAKTSTRS-SAKTLKNRPCLSPKHPT 416
Query: 938 EGGSTP--RPPEDALSGD--SDVDTASTVSLRSGKSG-----------------PSPTTP 976
G S P +P A+ + S S+V+ R+G SG P P
Sbjct: 417 PGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAP 476
Query: 977 QPLRAQKEM----SPSPPAAQDPGGTALVSAREQSSERQHHPLGPTDMGRGEPVRRSAIR 1032
+ Q + +PPA + P +A + +R+ P GP RGEP +S R
Sbjct: 477 PGQKGQANATRIPAKTPPAPKTPPSSA-----TKQVQRRPPPAGPRS-ERGEP-PKSGDR 529
Query: 1033 RGHRPRGSLDWP-SEERGPVLAHLPSSD--VMASNHETPEATGAGRLGSRRKPAAPPPSP 1089
G+ GS P S R P L P+ + +A P++ + + R AP P P
Sbjct: 530 SGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAK---SRLQTAPVPMP 586
Query: 1090 AAREEQSR 1097
+ +S+
Sbjct: 587 DLKNVKSK 594
>gi|73476377 LBXCOR1 homolog [Homo sapiens]
Length = 921
Score = 55.5 bits (132), Expect = 4e-07
Identities = 90/383 (23%), Positives = 129/383 (33%), Gaps = 62/383 (16%)
Query: 782 GRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQ-----TAQPSPPARDGV 836
G P EP S ++ + LSR PL G E L P PPAR G
Sbjct: 487 GAPEPLDGAEPAKESGLGAEERCPSALSRGPLDEDGTDEALPPPLAPLPPPPPPPARKGS 546
Query: 837 YVSANGRMVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGP-PAPGKPPHISSHPLLQDL 895
YVSA RP +E++ PA GP P G ++S L +
Sbjct: 547 YVSA-------FRPVVKDTESIAKLYGSAREAYGAGPARGPGPGAGSGGYVSPDFLSEGS 599
Query: 896 AATRAARMDFHSQDTHLILKETETALAALEARLLSNSVDAECEGGSTPRPPEDALSGDSD 955
++ +A D + D VD E + R P+D D+
Sbjct: 600 SSYNSASPDVDTAD--------------------EPEVDVE-----SNRFPDDE---DAQ 631
Query: 956 VDT-ASTVSLRSGKSGPSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAREQSSERQHHP 1014
+T S S G G PT PP+A G ++ + S R
Sbjct: 632 EETEPSAPSAGGGPDGEQPT-------------GPPSATSSGADGPANSPDGGSPRPRRR 678
Query: 1015 LGPTDMGR---GEPVRRSAIRRGHR--PRGSLDWPSEER-GPVLAHLPSSDVMASNHETP 1068
LGP GR G+ +RR R P G + E GP+ P+ V A +
Sbjct: 679 LGPPPAGRPAFGDLAAEDLVRRPERSPPSGGGGYELREPCGPLGGPAPAK-VFAPERDEH 737
Query: 1069 EATGAGRLGSRRKPAAPPPSPAAREEQSRSSASSQKGPQALTRSNSLSTPRPTRASRLRR 1128
+ A LG P + +E + S A + ++ S+S P P R
Sbjct: 738 VKSAAVALGPAASYVCTPEAHEPDKEDNHSPADDLETRKSYPDQRSISQPSPANTDRGED 797
Query: 1129 ARLGDASDTEAADGERGSLGNPE 1151
D + T + + +L E
Sbjct: 798 GLTLDVTGTHLVEKDIENLAREE 820
Score = 36.2 bits (82), Expect = 0.25
Identities = 63/237 (26%), Positives = 84/237 (35%), Gaps = 58/237 (24%)
Query: 726 PELDSEQ---PSRLFGQEELDPDSLSDASGSDGGR--GPEPGVEP-QDSRRRSPQEGPTW 779
PE+D E P QEE +P + S G DG + GP D SP G
Sbjct: 615 PEVDVESNRFPDDEDAQEETEPSAPSAGGGPDGEQPTGPPSATSSGADGPANSPDGGSPR 674
Query: 780 SRGRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVS 839
R R P G P GD LAA E L + + SPP+ G Y
Sbjct: 675 PRRRLGPPPAGRPA-----FGD-----------LAA----EDLVRRPERSPPSGGGGY-- 712
Query: 840 ANGRMVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSHPLLQDLAATR 899
+LR P GPAPA + AP + H+ S + AA+
Sbjct: 713 -------ELREPCGP-LGGPAPAKVF-------------APERDEHVKSAAVALGPAASY 751
Query: 900 AARMDFH---SQDTHLILKETETALAALEARLLSNSVDAECEGGSTPRPPEDALSGD 953
+ H +D H + ET + + R +S A + G ED L+ D
Sbjct: 752 VCTPEAHEPDKEDNHSPADDLETRKSYPDQRSISQPSPANTDRG------EDGLTLD 802
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 55.1 bits (131), Expect = 5e-07
Identities = 123/491 (25%), Positives = 157/491 (31%), Gaps = 75/491 (15%)
Query: 712 PAGPESSRRSGPGPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPE--PGVEPQDSR 769
P GP S R PGPP Q + E +P ASG G RGP PG D
Sbjct: 180 PMGP-SGPRGLPGPPGAPGPQGFQGPPGEPGEPG----ASGPMGPRGPPGPPGKNGDDGE 234
Query: 770 RRSPQEGPTWSRGRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLA----APGDGEGLGQT 825
P GR R P P A G + + + A GD G
Sbjct: 235 AGKP--------GRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPK 286
Query: 826 AQPSPPARDGVYVSANGRMVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPH 885
+P P +G A G+M + PG P P PA R A+GPP P P
Sbjct: 287 GEPGSPGENG----APGQMGPRGLPGERGRPGAPGPAGARGNDGATG-AAGPPGPTGPAG 341
Query: 886 ISSHPLLQDLAATRAARMDFHSQDTHLILKETETALAALEARLLSNSVDAECEGGSTPRP 945
P + S+ + E A A N G+ +P
Sbjct: 342 PPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNP-------GADGQP 394
Query: 946 PEDALSGDSDVDTASTVSLRSGKSGPSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSARE 1005
+G + A G SGP P K S P A G T + E
Sbjct: 395 GAKGANGAPGIAGAPGFPGARGPSGPQGPGGPP--GPKGNSGEPGAPGSKGDTG--AKGE 450
Query: 1006 QSSERQHHPLGPTDMGRGEPVRRSAIRRGHRPRGSLDWPSEERGPVLAHLPSSDVMAS-- 1063
P GP GE +R A R P G P E GP P +D +A
Sbjct: 451 PGPVGVQGPPGPA----GEEGKRGA-RGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPK 505
Query: 1064 ----NHETPEATG-------AGRLGSRRKPAAP-----PPSPAAREEQSRSSASSQKG-- 1105
+P G AGR G P A P SP + + Q G
Sbjct: 506 GPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRP 565
Query: 1106 -----PQALTRSNSLSTPRPTRASRLRRARLGD--------ASDTEAADGERGSLGNPEP 1152
P A ++ + P P A+ + G+ A DGE G+ G P P
Sbjct: 566 GPPGPPGARGQAGVMGFPGPKGAAG-EPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGP 624
Query: 1153 VGRPAAEQAKK 1163
G PA E+ ++
Sbjct: 625 AG-PAGERGEQ 634
Score = 53.9 bits (128), Expect = 1e-06
Identities = 140/589 (23%), Positives = 171/589 (29%), Gaps = 99/589 (16%)
Query: 640 GAAPQAEHQGLPVPGSPGGQKWVSRWASLADSYSDPGLT----EDGL-GRRGGE-PEGSL 693
G A QGLP P P G+ + PG + E G G RG + P G
Sbjct: 635 GPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPA 694
Query: 694 PVRMRRRLPQLPSERADSPAGPESSRRSGPGPPELDSEQ-----PSRLFGQEELDPDSLS 748
R P + D+ A + PG + E+ P + + P
Sbjct: 695 GPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGAD 754
Query: 749 DASGSDGGRG-------PEPGVEPQDSRRRSPQ--EGPTWSRGRRSPRA-PGEPTPASFF 798
+ G DG RG P P P D P GPT +RG R PG P PA F
Sbjct: 755 GSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAG-F 813
Query: 799 IGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSP---------------PARDGV------- 836
G D K PGD G P P P G
Sbjct: 814 AGPPGADGQPGAK--GEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPP 871
Query: 837 ----YVSANGRMVIQLRPGRSPEPDGPAPAFLRQESFTK---EPAS-----GPPAPGKPP 884
+ A GR+ G + P P PA + PA GPP P P
Sbjct: 872 GATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPA 931
Query: 885 HISSHPLLQDLAATRAARMDFHSQDTHLILKETETALAALEARLLSNSVDAECEGGSTPR 944
P A T R + E G
Sbjct: 932 GEKGSPGADGPAGAPG----------------TPGPQGIAGQRGVVGLPGQRGERGFPGL 975
Query: 945 PPEDALSGDSDVDTASTVSLRSGKSGPSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAR 1004
P G AS G GP P + +E +P + G+
Sbjct: 976 PGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGD 1035
Query: 1005 EQSSERQHHPLGPTDMGRGEPVRRSAIRRGHRPRGSLDWPSEERGPVLAHLPS--SDVMA 1062
+ P P G PV A + G R P+ GPV A P+
Sbjct: 1036 RGETGPAGPPGAPGAPGAPGPV-GPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRG 1094
Query: 1063 SNHETPEATGAGRLGSR-----RKPAAPPPSPAAREEQSRSSASSQKGPQALTRSNSLST 1117
ET E G G R + P PP SP EQ S AS GP+ S
Sbjct: 1095 DKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPG---EQGPSGASGPAGPRG--PPGSAGA 1149
Query: 1118 PRPTRASRL--------RRARLGDASDTEAADGERGSLGNPEPVGRPAA 1158
P + L R R GDA G G G P P G P+A
Sbjct: 1150 PGKDGLNGLPGPIGPPGPRGRTGDAGPV----GPPGPPGPPGPPGPPSA 1194
Score = 48.5 bits (114), Expect = 5e-05
Identities = 126/517 (24%), Positives = 155/517 (29%), Gaps = 102/517 (19%)
Query: 683 GRRGGEPEGSLPVRMRRRLPQLPSERADSPAGPESSRRSGPGPPELDSE-QPSRLFGQEE 741
G RG P G R +P P P GP PGPP L P +G +E
Sbjct: 118 GPRG--PRGPAGPPGRDGIPGQPG--LPGPPGPPGP----PGPPGLGGNFAPQLSYGYDE 169
Query: 742 LDPDSLS-----DASGSDGGRGPEPGVEPQDSRRRSPQEGPTWSRGRRSPRAPGEPTPAS 796
+S SG G GP PQ + + G + G PR P P
Sbjct: 170 KSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPP--- 226
Query: 797 FFIGDQNGDAVLSRKP-----------------------------------LAAPGDGEG 821
+NGD + KP A GD
Sbjct: 227 ----GKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGP 282
Query: 822 LGQTAQPSPPARDGVYVSANGRMVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGPPAPG 881
G +P P +G A G+M + PG P P PA R A+GPP P
Sbjct: 283 AGPKGEPGSPGENG----APGQMGPRGLPGERGRPGAPGPAGARGND-GATGAAGPPGPT 337
Query: 882 KPPHISSHPLLQDLAATRAARMDFHSQDTHLILKETETALAALEARLLSNSVDAECEGGS 941
P P + S+ + E A A N G+
Sbjct: 338 GPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNP-------GA 390
Query: 942 TPRPPEDALSGDSDVDTASTVSLRSGKSGPSPTTPQPLRAQKEMSPSPPAAQDPGGTALV 1001
+P +G + A G SGP P K S P A G T
Sbjct: 391 DGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPP--GPKGNSGEPGAPGSKGDTG-- 446
Query: 1002 SAREQSSERQHHPLGPTDMGRGEPVRRSAIRRGHRPRGSLDWPSEERGPVLAHLPSSDVM 1061
+ E P GP GE +R A R P G P E GP P +D +
Sbjct: 447 AKGEPGPVGVQGPPGPA----GEEGKRGA-RGEPGPTGLPGPPGERGGPGSRGFPGADGV 501
Query: 1062 ASNHETPEATGAGRLGSRRKPAAPPPSPAAREEQSRSSASSQKGPQALTRSNSLSTPRPT 1121
A P+ AG GS PA P SP E R + G + LT S +P P
Sbjct: 502 AG----PKGP-AGERGS-PGPAGPKGSPG---EAGRPGEAGLPGAKGLT--GSPGSPGP- 549
Query: 1122 RASRLRRARLGDASDTEAADGERGSLGNPEPVGRPAA 1158
G G G P P G P A
Sbjct: 550 -------------DGKTGPPGPAGQDGRPGPPGPPGA 573
Score = 46.6 bits (109), Expect = 2e-04
Identities = 182/820 (22%), Positives = 242/820 (29%), Gaps = 148/820 (18%)
Query: 428 GDPKADKRRGPT--PADRDRPSVPAPVQAGGRSSGPQRAGSLKREKTEERLGSP----SP 481
G+ A + GP P +R RP P P A G AG G P +
Sbjct: 293 GENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAK 352
Query: 482 ASRTPARPFGSVGRRSRLAQDFMAQCLRESSPAARPSPE---------KVPPVLPAPLTP 532
P P GS G + + + PA P + P + AP P
Sbjct: 353 GEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFP 412
Query: 533 HGTSPVGPPTP--PPAPTDPQLTKARKQEEDDSLSDAGTYTIETEAQDTEVEEARKMIDQ 590
P GP P PP P + D+ + + + E K
Sbjct: 413 GARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKR--- 469
Query: 591 VFGVLESPELSRASSATFRPVIRGDRDESDDGGVAQRMALLQEFASRPLGAAPQAEHQGL 650
G P T P G+R GG R + + P G A + G
Sbjct: 470 --GARGEP------GPTGLPGPPGER-----GGPGSRGFPGADGVAGPKGPAGERGSPGP 516
Query: 651 PVP-GSPG-----GQKWVSRWASLADSYSDPGLTEDGL----------GRRGGEPEGSLP 694
P GSPG G+ + L S PG DG GR G P G
Sbjct: 517 AGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPG--PDGKTGPPGPAGQDGRPG--PPGPPG 572
Query: 695 VRMRRRLPQLPSERADSPAGPESSRRSGPGPP----------ELDSEQPSRLFG----QE 740
R + + P + + ++ R PGPP E ++ P G +
Sbjct: 573 ARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERG 632
Query: 741 ELDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQE----GPTWSRGRRSPRAPGE----- 791
E P G G GP PG + + P + GP+ +RG R PGE
Sbjct: 633 EQGPAGSPGFQGLPGPAGP-PGEAGKPGEQGVPGDLGAPGPSGARGERG--FPGERGVQG 689
Query: 792 -PTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSANGRMVIQLRP 850
P PA R APG+ G P P G A G +Q P
Sbjct: 690 PPGPAG------------PRGANGAPGNDGAKGDAGAPGAPGSQG----APG---LQGMP 730
Query: 851 GRSPEPDGPAPAFLRQESFTK----EPAS----------GPPAPGKPPHISSHPLLQDLA 896
G P P R ++ K P GPP P P A
Sbjct: 731 GERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPA 790
Query: 897 ---ATRAARMDFHSQDTHLILKETETALAALEARLLSNSVDAECEGGSTPRPPEDALSGD 953
R A D A + DA +G + P P
Sbjct: 791 GPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPP 850
Query: 954 SDVDTASTVSLRS--GKSGPSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAREQSSERQ 1011
+ + G +GP T P A + P P P G + +E
Sbjct: 851 GPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEG----- 905
Query: 1012 HHPLGPTDMGRGEPVRRSAIRRGHRPRGSLDWPSEERGPVLAHLPSSDVMASNHETPEAT 1071
G G P R P G P+ E+G P +D A TP
Sbjct: 906 ----GKGPRGETGPAGRPGEVGPPGPPG----PAGEKGS-----PGADGPAGAPGTPGPQ 952
Query: 1072 G----------AGRLGSRRKPAAPPPSPAAREEQSRSSASSQKGPQALTRSNSLSTPRPT 1121
G G+ G R P P PS +Q S AS ++GP L+ P P
Sbjct: 953 GIAGQRGVVGLPGQRGERGFPGLPGPS-GEPGKQGPSGASGERGPPGPMGPPGLAGP-PG 1010
Query: 1122 RASRLRRARLGDASDTEAADGERGSLGNPEPVGRPAAEQA 1161
+ R + + + G +G G P G P A A
Sbjct: 1011 ESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGA 1050
Score = 41.2 bits (95), Expect = 0.008
Identities = 63/223 (28%), Positives = 82/223 (36%), Gaps = 36/223 (16%)
Query: 418 RSQSFTHSPSGDPKADKRRGPT-PADR--DR----PSVPA----PVQAGGRSSGPQRAGS 466
R ++ P G P A GP PA + DR P+ PA PV A G +GPQ
Sbjct: 1036 RGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARG-PAGPQGPRG 1094
Query: 467 LKREKTEE-----RLGSPSPASRTPARPFGSVGRRSRLAQDFMAQCLRESSPAARPSPEK 521
K E E+ + + P P GS G + A A P +
Sbjct: 1095 DKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDG 1154
Query: 522 VPPVLPAPLTPHG-------TSPVGPPTPPPAPTDPQLTKA------RKQEEDDSLSDAG 568
+ LP P+ P G PVGPP PP P P A Q + D G
Sbjct: 1155 LNG-LPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSAGFDFSFLPQPPQEKAHDGG 1213
Query: 569 TYTIETEA-----QDTEVEEARKMIDQVFGVLESPELSRASSA 606
Y +A +D EV+ K + Q + SPE SR + A
Sbjct: 1214 RYYRADDANVVRDRDLEVDTTLKSLSQQIENIRSPEGSRKNPA 1256
Score = 37.0 bits (84), Expect = 0.15
Identities = 121/534 (22%), Positives = 161/534 (30%), Gaps = 123/534 (23%)
Query: 419 SQSFTHSPSGDPKADKRRGPT-PADRD-RPSVPAPVQAGGRSS-----GPQRAGSLKREK 471
++ T SP G P D + GP PA +D RP P P A G++ GP+ A +
Sbjct: 537 AKGLTGSP-GSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKA 595
Query: 472 TEERLGSP----SPASRT----------PARPFGSVGRRSRLAQDFMAQCLRESSP---A 514
E + P PA + PA P G G + + P A
Sbjct: 596 GERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEA 655
Query: 515 ARPSPEKVPPVLPAPLTPHGTSPVGPPTP-----PPAPTDPQLTKARKQEEDDSLSDAGT 569
+P + VP L AP G P PP P P+ D + DAG
Sbjct: 656 GKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGN-DGAKGDAGA 714
Query: 570 YTIETEA-----QDTEVEEARKMIDQVFGVLESPELSRASSATFRPVIRG---------- 614
Q E + G A + + +RG
Sbjct: 715 PGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGP 774
Query: 615 -----DRDESDDGGVAQRMALLQEFASRPLGAAPQAEHQGLPVPGSPGGQKWVSRWASLA 669
D+ ES G A P GA +G P P P G +A
Sbjct: 775 AGAPGDKGESGPSGPAG-----------PTGARGAPGDRGEPGPPGPAG------FAGPP 817
Query: 670 DSYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERADSPAGPESSRRSGP------ 723
+ PG + G G + + P P P +P + +GP
Sbjct: 818 GADGQPGAKGEP-GDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGF 876
Query: 724 -------GPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQEG 776
GPP PS G P +G +GG+GP + G
Sbjct: 877 PGAAGRVGPPG-----PSGNAG-----PPGPPGPAGKEGGKGPR------------GETG 914
Query: 777 PTWSRGRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGV 836
P G P PG P PA G++ + P APG G Q G
Sbjct: 915 PAGRPGEVGP--PGPPGPA----GEKGSPG--ADGPAGAPGTPGPQGIAGQRGVVGLPG- 965
Query: 837 YVSANGRMVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSHP 890
G PG S EP P+ E GPP P PP ++ P
Sbjct: 966 ---QRGERGFPGLPGPSGEPGKQGPSGASGE-------RGPPGPMGPPGLAGPP 1009
Score = 36.6 bits (83), Expect = 0.19
Identities = 70/302 (23%), Positives = 94/302 (31%), Gaps = 58/302 (19%)
Query: 608 FRPVIRGDRDESDDGGVAQRMALLQEFASRPLGAAPQAEHQGLP-VPGSPGGQKWVSRWA 666
F P + DE GG++ P+G + +GLP PG+PG Q +
Sbjct: 159 FAPQLSYGYDEKSTGGIS---------VPGPMGPSGP---RGLPGPPGAPGPQGFQGPPG 206
Query: 667 SLADSYSDPGLTEDGL----GRRGGEPEGSLPVRMRRRLPQLPSERADSPA-----GPES 717
+ + + G G+ G + E P R R P P P G +
Sbjct: 207 EPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKG 266
Query: 718 SRR----------SGPGPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPEPGVEPQD 767
R +GP P+ + P ++ P L G G GP G D
Sbjct: 267 HRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGP-AGARGND 325
Query: 768 SRRRSPQEGPTWSRGRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQ 827
G T + G P P P +G G+A P G G +
Sbjct: 326 --------GATGAAGPPGPTGPAGPPGFPGAVG-AKGEA----GPQGPRGSEGPQGVRGE 372
Query: 828 PSPPARDGVYVSANGRMVIQLRPGRSPEPDGP----APAFLRQESFT-KEPASGPPAPGK 882
P PP G A PG +P AP F SGP PG
Sbjct: 373 PGPPGPAGAAGPAG-------NPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGG 425
Query: 883 PP 884
PP
Sbjct: 426 PP 427
Score = 34.7 bits (78), Expect = 0.74
Identities = 27/83 (32%), Positives = 31/83 (37%), Gaps = 2/83 (2%)
Query: 717 SSRRSGPGPPELDSEQ-PSRLFGQE-ELDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQ 774
S + PGPP EQ PS G P + A G DG G + P R R+
Sbjct: 1114 SGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGD 1173
Query: 775 EGPTWSRGRRSPRAPGEPTPASF 797
GP G P P P A F
Sbjct: 1174 AGPVGPPGPPGPPGPPGPPSAGF 1196
>gi|157785645 SPEG complex locus [Homo sapiens]
Length = 3267
Score = 54.7 bits (130), Expect = 7e-07
Identities = 150/605 (24%), Positives = 208/605 (34%), Gaps = 96/605 (15%)
Query: 685 RGGEPEGSLPVRMRRRLPQLPSERADSPAGPESSRRSGPGPPELDSEQPSRLFGQEELDP 744
RGG EG R++ +L GPE + SG P L+S G DP
Sbjct: 2055 RGGLGEGEYAQRLQALRQRLLR------GGPEDGKVSGLRGPLLES------LGGRARDP 2102
Query: 745 DSLSDASGSDGGRGPEPGVEPQDSRRRSPQEGPTWSRGRRSPRAPGEPTPASFFIGDQNG 804
++ A+ S+ +P +E R Q+ ++S+G PR A I
Sbjct: 2103 -RMARAASSEAAPHHQPPLE-----NRGLQKSSSFSQGEAEPRGRHRRAGAPLEIPV--- 2153
Query: 805 DAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSANGRMVIQLRPGRSPEPDGPAPAFL 864
A L + L L + AQPS PAR +P+P P A
Sbjct: 2154 -ARLGARRLQESPSLSALSE-AQPSSPARPS-----------------APKPSTPKSA-- 2192
Query: 865 RQESFTKEPASGPPAPGKPPHISSHPLLQDLAATRAARMDFHSQDTHLILKETETALAAL 924
+ T A PPAP + P + + A++ A Q L L + +L
Sbjct: 2193 EPSATTPSDAPQPPAPQPAQDKAPEPRPEPVRASKPAPPPQALQTLALPLTPYAQIIQSL 2252
Query: 925 EARLLSNSVDAECEGGSTPRPPEDALSGDSDVDTASTVSLRSGKSGPSPTTPQPLRAQKE 984
+ LS +G + P P E AS K PS P P+ A+K
Sbjct: 2253 Q---LSGHAQGPSQGPAAP-PSEPKPHAAVFARVASPPPGAPEKRVPSAGGP-PVLAEKA 2307
Query: 985 MSPSPPAAQDPGGTALVSAREQSSERQHHPLGPTDMGRGEPVRRSAIRRGHRPRGSLDWP 1044
P+ P PG + S SE + + R S + G R
Sbjct: 2308 RVPTVPPR--PGSSLSSSIENLESEAVFE-------AKFKRSRESPLSLGLRLLSRS--R 2356
Query: 1045 SEERGPVLAHLPSSDVMASNHETPEATGAGRLGSRRKPAAPPPSPAAREEQSRSSASSQK 1104
SEERGP + R PA P R E+SRS +
Sbjct: 2357 SEERGPFRGAEEEDGIY-----------------RPSPAGTPLELVRRPERSRSVQDLRA 2399
Query: 1105 -GPQALTRSNSLSTPRPTRASRLRRARLGDASDTEAADGERGSLGNPEPVGRPAAEQAKK 1163
G L R SLS + R R A+ A + DGE S G G P ++
Sbjct: 2400 VGEPGLVRRLSLSLSQ--RLRRTPPAQRHPAWEARGGDGE-SSEGGSSARGSPVLAMRRR 2456
Query: 1164 LS-RLDILAMPRKRAGSFTGTSDPEAAPARTSFSGRSVELCCASRKPTMAEARAVSRKAA 1222
LS L+ L+ +R+GS + D A SGRS L R+ T +E ++ R
Sbjct: 2457 LSFTLERLSSRLQRSGS---SEDSGGA------SGRSTPLFGRLRRAT-SEGESLRRLGL 2506
Query: 1223 ---NTATTTGPRQPFSRARSGSARYTSTTQTPRAGSSSRARSRAPGPRDTDDDEEEPDPY 1279
A G P + + A TS + P SR+R R R D P
Sbjct: 2507 PHNQLAAQAGATTPSAESLGSEASATSGSSAP---GESRSRLRWGFSRPRKDKGLSPPNL 2563
Query: 1280 GFIVQ 1284
VQ
Sbjct: 2564 SASVQ 2568
Score = 45.4 bits (106), Expect = 4e-04
Identities = 96/427 (22%), Positives = 147/427 (34%), Gaps = 87/427 (20%)
Query: 945 PPEDALSGDSDVDTASTVSLRSGKSGPSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAR 1004
PP LS SD + L P+ P+PL Q E S S + D
Sbjct: 1913 PPSGGLSSSSDSEEEELEEL--------PSVPRPL--QPEFSGSRVSLTD---------- 1952
Query: 1005 EQSSERQHHPLGPTDMGRGEPVRRSAIRRGHRPRGSLDWPSEERGPVL-AHLPSSDVMAS 1063
+ LG + G P +DW + R P PS + + S
Sbjct: 1953 ---IPTEDEALGTPETGAATP---------------MDWQEQGRAPSQDQEAPSPEALPS 1994
Query: 1064 NHETPEATGAGRLGSRRKPAAPPPSPAAREEQSRSSASSQKGPQALTRS--NSLSTPRPT 1121
+ P A + R G R+ + S SA + GP+ L R + S P
Sbjct: 1995 PGQEPAAGASPRRGELRRGS------------SAESALPRAGPRELGRGLHKAASVELPQ 2042
Query: 1122 R------ASRLRRARLGDASDTEAADGERGSL--GNPEPVGRPAAEQAKKLSRLDILAMP 1173
R A+RL R LG+ + R L G PE G+ + + L L A
Sbjct: 2043 RRSPSPGATRLARGGLGEGEYAQRLQALRQRLLRGGPED-GKVSGLRGPLLESLGGRARD 2101
Query: 1174 RKRAGSFTGTSDPEAAPA--------RTSFSGRSVELCCASRKPTMAEARAVSRKAAN-- 1223
+ A + + + P P +SFS E R+ V+R A
Sbjct: 2102 PRMARAASSEAAPHHQPPLENRGLQKSSSFSQGEAEPRGRHRRAGAPLEIPVARLGARRL 2161
Query: 1224 ----TATTTGPRQPFSRARSGSARYTSTTQTPRAGSSSRARSRAPGPRDTDDDEEEPDPY 1279
+ + QP S AR + + ++ + ++ + P P+ D EP P
Sbjct: 2162 QESPSLSALSEAQPSSPARPSAPKPSTPKSAEPSATTPSDAPQPPAPQPAQDKAPEPRPE 2221
Query: 1280 GFIVQTAEIAEIARLSQTLVKDVAILAQEIHDVAGDGDTLGSSE-PA--------HSASL 1330
V+ ++ A + QTL + AQ I + G G S+ PA H+A
Sbjct: 2222 P--VRASKPAPPPQALQTLALPLTPYAQIIQSLQLSGHAQGPSQGPAAPPSEPKPHAAVF 2279
Query: 1331 SNMPSTP 1337
+ + S P
Sbjct: 2280 ARVASPP 2286
Score = 44.3 bits (103), Expect = 0.001
Identities = 128/508 (25%), Positives = 173/508 (34%), Gaps = 93/508 (18%)
Query: 427 SGDPKADKRRGPTPADRDRPSVPAPVQAGGRSSGPQRAG--SLKREKTEERLGSP--SPA 482
SG ++ G R P P QA G +GP+ G L R +G+ S
Sbjct: 190 SGQTVLEQEAGSGGGTRRLPGSPRQAQATG--AGPRHLGVEPLVRASRANLVGASWGSED 247
Query: 483 SRTPARP-FGSV-----GRRSRLAQDFMAQCLRESSPAARPS--------PEKVPP---- 524
S + A +GS GR + LR P +P P + PP
Sbjct: 248 SLSVASDLYGSAFSLYRGRALSIHVSVPQSGLRREEPDLQPQLASEAPRRPAQPPPSKSA 307
Query: 525 VLPAPLTPHGT-SPVGPPTPPPA-PTDPQ------------LTKARKQEEDDSLSDAGTY 570
+LP P G SP GPP P A PT P T+ ++ ++ S +
Sbjct: 308 LLPPPSPRVGKRSPPGPPAQPAATPTSPHRRTQEPVLPEDTTTEEKRGKKSKSSGPSLAG 367
Query: 571 TIETEAQDTEVEEARKMIDQVFGVLESPELSRASSAT-----FRPVIRGDRDESDDGG-- 623
T E+ Q T + EA + + SP L RA S F R + SD
Sbjct: 368 TAESRPQ-TPLSEASGRLSALG---RSPRLVRAGSRILDKLQFFEERRRSLERSDSPPAP 423
Query: 624 ----VAQRMALLQEFASRPLGA---APQAEHQGLPVPGSPGGQK--WVSRWASLADSYSD 674
V R A E GA P A + L PGS ++ + + ASL +
Sbjct: 424 LRPWVPLRKARSLEQPKSERGAPWGTPGASQEELRAPGSVAERRRLFQQKAASLDERTRQ 483
Query: 675 PGLTED-------GLGRRGGEPEGSLPVR----MRRRLPQLPSERADS-------PAGPE 716
D LGR VR +R L + PS R P+ P+
Sbjct: 484 RSPASDLELRFAQELGRIRRSTSREELVRSHESLRATLQRAPSPREPGEPPLFSRPSTPK 543
Query: 717 SSRRSGPGPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQEG 776
+SR P + S + G E P S A ++ G GP+ V RR Q
Sbjct: 544 TSRAVSPAAAQPPSPSSAEKPGDEPGRPRSRGPAGRTEPGEGPQQEV------RRRDQFP 597
Query: 777 PTWSRGRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLA-----APGDGEGLGQTAQPSPP 831
T SR + R+P P A R+P A P GL A P
Sbjct: 598 LTRSRAIQECRSPVPPPAADPPEARTKAPPGRKREPPAQAVRFLPWATPGLEGAAVPQTL 657
Query: 832 ARDGVYVSANGRMVIQLRPGRSPEPDGP 859
++ A R+ R PE DGP
Sbjct: 658 EKNRAGPEAEKRL------RRGPEEDGP 679
Score = 36.6 bits (83), Expect = 0.19
Identities = 46/186 (24%), Positives = 69/186 (37%), Gaps = 33/186 (17%)
Query: 718 SRRSGPGPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQEGP 777
+ R+G GP SE ++F + D ++ A+ + P R P + P
Sbjct: 2751 ANRAGQGPFSNSSE---KVFVRGTQDSSAVPSAAHQEAPVTSRPA-------RARPPDSP 2800
Query: 778 TWSRGRRSPRAPGEPTPASFFIGDQN-----GDAVLSRK-----PLAAPGDGEGLGQTAQ 827
T P AP PTP S + + A+ S K P P GL Q A+
Sbjct: 2801 T---SLAPPLAPAAPTPPSVTVSPSSPPTPPSQALSSLKAVGPPPQTPPRRHRGL-QAAR 2856
Query: 828 PSPPARDGVYVSANGRMVIQLR-----PGRSPEPDGPA----PAFLRQESFTKEPASGPP 878
P+ P +V+ + L P +P+ P P ++ + PA PP
Sbjct: 2857 PAEPTLPSTHVTPSEPKPFVLDTGTPIPASTPQGVKPVSSSTPVYVVTSFVSAPPAPEPP 2916
Query: 879 APGKPP 884
AP PP
Sbjct: 2917 APEPPP 2922
Score = 35.4 bits (80), Expect = 0.43
Identities = 111/547 (20%), Positives = 180/547 (32%), Gaps = 71/547 (12%)
Query: 357 GTQSDSEDPLAKAASAAGVPLEA-SGEQVRLQRQIKRDPQELLHNQQAFVIEFFDEDTPR 415
G SED L+ A+ G G + + + PQ L ++ + + PR
Sbjct: 240 GASWGSEDSLSVASDLYGSAFSLYRGRALSIHVSV---PQSGLRREEPDLQPQLASEAPR 296
Query: 416 KKRSQSFTHS---PSGDPKADKRRGPTPADRDRPSVPAPVQAGGRSSGPQRAGSLKREKT 472
+ + S P P+ KR P P + + +P + P+ + ++
Sbjct: 297 RPAQPPPSKSALLPPPSPRVGKRSPPGPPAQPAATPTSPHRRTQEPVLPEDTTTEEKRGK 356
Query: 473 EERLGSPSPASRTPARP----FGSVGRRSRLAQDFMAQCLRESSPAARPSPEKVPPVLPA 528
+ + PS A +RP + GR S L + SP + ++ L
Sbjct: 357 KSKSSGPSLAGTAESRPQTPLSEASGRLSALGR----------SPRLVRAGSRILDKL-- 404
Query: 529 PLTPHGTSPVGPPTPPPAPTDP--QLTKARKQEEDDSLSDAGTYTIETEAQDT----EVE 582
+ PPAP P L KAR E+ S A T ++ V
Sbjct: 405 QFFEERRRSLERSDSPPAPLRPWVPLRKARSLEQPKSERGAPWGTPGASQEELRAPGSVA 464
Query: 583 EARKMIDQVFGVLESPELSRASSATFRPVIRGDRDESDDGGVAQRMALLQEFASRPLGAA 642
E R++ Q L+ R+ ++ + + + E L A
Sbjct: 465 ERRRLFQQKAASLDERTRQRSPASDLELRFAQELGRIRRSTSREELVRSHESLRATLQRA 524
Query: 643 PQAEHQGLPV----PGSPGGQKWVSRWASLADSYSDPGLTEDGLGR------RGGEPEGS 692
P G P P +P + VS A+ S S D GR G G
Sbjct: 525 PSPREPGEPPLFSRPSTPKTSRAVSPAAAQPPSPSSAEKPGDEPGRPRSRGPAGRTEPGE 584
Query: 693 LPVRMRRRLPQLPSERADS---------PAGPESSRRSGPGPPELDSEQPSRLFGQEELD 743
P + RR Q P R+ + P + PP E P++
Sbjct: 585 GPQQEVRRRDQFPLTRSRAIQECRSPVPPPAADPPEARTKAPPGRKREPPAQAVRFLPWA 644
Query: 744 PDSLSDASGSDGGRGPEPGVEPQDSRRRSPQEGPTWS----RGRRS--------PRAPGE 791
L A+ G E + RR P+E W RG RS P +P
Sbjct: 645 TPGLEGAAVPQTLEKNRAGPEAEKRLRRGPEEDGPWGPWDRRGARSQGKGRRARPTSPEL 704
Query: 792 PTPASFFI--GDQNGDAVLSRKPL----AAPGDGEGLGQTAQPSPPA-----RDGVYVSA 840
+ ++ G++ +A + PL APG L +PP +DG + +
Sbjct: 705 ESSDDSYVSAGEEPLEAPVFEIPLQNVVVAPGADVLLKCIITANPPPQVSWHKDGSALRS 764
Query: 841 NGRMVIQ 847
GR++++
Sbjct: 765 EGRLLLR 771
Score = 35.4 bits (80), Expect = 0.43
Identities = 32/132 (24%), Positives = 49/132 (37%), Gaps = 7/132 (5%)
Query: 428 GDPKADKRRGPTPADRDRPSVPAPVQAGGRSSGPQRAGSLKREKTEERLGSPSPASRTPA 487
G D R + P P++ + G Q++ S + + E R G A
Sbjct: 2096 GGRARDPRMARAASSEAAPHHQPPLE----NRGLQKSSSFSQGEAEPR-GRHRRAGAPLE 2150
Query: 488 RPFGSVGRRSRLAQDFMAQCLRESSPAARPSPEKVPPVLPAPLTPHGTSPVGPPTPP-PA 546
P +G R RL + L E+ P++ P P P P T+P P PP P
Sbjct: 2151 IPVARLGAR-RLQESPSLSALSEAQPSSPARPSAPKPSTPKSAEPSATTPSDAPQPPAPQ 2209
Query: 547 PTDPQLTKARKQ 558
P + + R +
Sbjct: 2210 PAQDKAPEPRPE 2221
Score = 33.1 bits (74), Expect = 2.1
Identities = 73/340 (21%), Positives = 109/340 (32%), Gaps = 70/340 (20%)
Query: 236 PSQPPEVPAHEMPTKDAEAGGGGAAP---VVQSHASFTIEFDDCSPGKMKIKDH-ITKFS 291
PSQ E P+ E + GA+P ++ +S P ++ H
Sbjct: 1980 PSQDQEAPSPEALPSPGQEPAAGASPRRGELRRGSSAESALPRAGPRELGRGLHKAASVE 2039
Query: 292 LRQRRPPGKEATPGEMVSAETKVADWLVQNDPSLLHRVGPGDDRHSTKSDLPVHTRTLKG 351
L QRR P AT L R G G+ ++ + + R L+G
Sbjct: 2040 LPQRRSPSPGATR---------------------LARGGLGEGEYAQRLQA-LRQRLLRG 2077
Query: 352 HKHEDGTQSDSEDPLAKAASAAGVPLEASGEQVRLQRQIKRDPQELLHNQQAFVIEFFDE 411
EDG S PL LE+ G + R R + E + Q +
Sbjct: 2078 GP-EDGKVSGLRGPL----------LESLGGRARDPRMARAASSEAAPHHQPPL------ 2120
Query: 412 DTPRKKRSQSFTHSPSGDPKADKRRGPTPADRDRPSVPAPVQAGGRSSGPQRAGSLKREK 471
+ ++S SF+ + +P+ RR P + +P R +L +
Sbjct: 2121 ENRGLQKSSSFSQGEA-EPRGRHRRAGAPLE-----IPVARLGARRLQESPSLSALSEAQ 2174
Query: 472 TEERLGSPSPASRTPARPFGSVGRRSRLAQDFMAQCLRESSPAARPSP----EKVPP--- 524
+P TP S S Q Q ++ +P RP P + PP
Sbjct: 2175 PSSPARPSAPKPSTPKSAEPSATTPSDAPQPPAPQPAQDKAPEPRPEPVRASKPAPPPQA 2234
Query: 525 --VLPAPLTP------------HGTSPVGPPTPPPAPTDP 550
L PLTP H P P PP+ P
Sbjct: 2235 LQTLALPLTPYAQIIQSLQLSGHAQGPSQGPAAPPSEPKP 2274
>gi|116268127 kinase non-catalytic C-lobe domain (KIND) containing 1
isoform a [Homo sapiens]
Length = 1749
Score = 54.7 bits (130), Expect = 7e-07
Identities = 71/277 (25%), Positives = 103/277 (37%), Gaps = 45/277 (16%)
Query: 841 NGRMVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSHPLLQDLAATRA 900
N V++L+P +P P+ P+P FL S T A P PG+ HP ++ A
Sbjct: 616 NAFSVVELKPSVAPAPE-PSPGFLPVNSDTGLVAVPGPVPGQ------HPCGEEATQLPA 668
Query: 901 ARMDFHSQDTHL--ILKETETALAALEARLLSNSVDAECEGGSTPRPPEDALSGDSDVDT 958
A F S+ TH I+ ++A + L ++E GG E+ LS ++ +
Sbjct: 669 A---FTSEATHFKPIVLAQNASVARDQPALAQE--ESEERGGQREGEGEEKLSLEAHAGS 723
Query: 959 ASTVSLRSGKSGPSP--TTPQPLRAQKEMS---------PSPPAAQDPGGTALVSAREQS 1007
S + GP P P+PL A + P PA Q G ++
Sbjct: 724 PSLKTPDGPVPGPGPQGAAPEPLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPGSPVP 783
Query: 1008 SERQHHPLGPTDMGRGEPVRRSAIRRGHRPRGSLDWPSEERGPVLAH--------LPSSD 1059
+ P + G EP+ G RP + GP AH P S
Sbjct: 784 APPTKASALPVEQGPAEPIPPGVASGGLRP--------DALGPTTAHHGPRHPPKPPRSK 835
Query: 1060 VMASNHETPEATGAGRLGSR--RKPAAPP--PSPAAR 1092
+ PE GA G R + P + P P PA R
Sbjct: 836 ATERPGQEPEGPGATPAGERDDQSPDSVPERPRPADR 872
Score = 40.8 bits (94), Expect = 0.010
Identities = 33/99 (33%), Positives = 41/99 (41%), Gaps = 6/99 (6%)
Query: 449 PAPVQAGGRSSGPQRAGSLKREKTEERLGSPSPASRTPARPFGSVGRRSRLAQDFMAQCL 508
PA Q G QR G EK + SP+ +TP P G + + A
Sbjct: 693 PALAQEESEERGGQREGE-GEEKLSLEAHAGSPSLKTPDGPVPGPGPQGAAPEPLGASVQ 751
Query: 509 RESSPAARPSPEKVPPVLPAPLTPHGTSPVGPPTPPPAP 547
R+S+ RP P PP PA P G S P +P PAP
Sbjct: 752 RDSAQG-RPCP---PPQAPAN-QPEGASSAAPGSPVPAP 785
Score = 38.1 bits (87), Expect = 0.067
Identities = 97/397 (24%), Positives = 141/397 (35%), Gaps = 89/397 (22%)
Query: 678 TEDGLGRRGGEPEGSLPVRMRRRLPQLPSERADSPAGPESSRRSGPGP----PELDSEQP 733
+E+ G+R GE E L + P L + P GP GPGP PE
Sbjct: 700 SEERGGQREGEGEEKLSLEAHAGSPSLKT-----PDGPVP----GPGPQGAAPEPLGASV 750
Query: 734 SRLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQEGP-TWSRGRRSPRAPGEP 792
R Q P + A+ +G PG SP P T + + P EP
Sbjct: 751 QRDSAQGRPCPPPQAPANQPEGASSAAPG---------SPVPAPPTKASALPVEQGPAEP 801
Query: 793 TPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSANGRMVIQLRPGR 852
P G DA+ P A G P PP R RPG+
Sbjct: 802 IPPGVASGGLRPDAL---GPTTAHH-----GPRHPPKPP-----------RSKATERPGQ 842
Query: 853 SPEPDGPAPAFLRQESFTKEPASGPPAPGKP-------PHISSHPL--------LQDLAA 897
PE G PA R + + P S P P +P P + + PL LQ+ A
Sbjct: 843 EPEGPGATPAGERDD---QSPDSVPERP-RPADRRLCLPCVDASPLPGRTACPSLQE--A 896
Query: 898 TRAARMDFHSQD------THLILKETETALAALEARLLSNSVDAE-CEGGSTPRPPEDAL 950
TR + +F LI+ E AL L ++ + C+ L
Sbjct: 897 TRLIQEEFAFDGYLDNGLEALIMGEYIFALKDLTFATFCGAISEKFCD-----------L 945
Query: 951 SGDSDVDTASTVSLRSGKSGPSPTTPQPLRAQKEMSPSP--PAAQDPG----GTALVSAR 1004
D + + + +G++ PSP+T + +Q E S SP P+++ P G +
Sbjct: 946 YWDEKL-LQNLFKVVNGQASPSPSTAEEAGSQLEGSQSPRSPSSKRPSLHRLGKEKPAMA 1004
Query: 1005 EQSSERQHHPLGPTDMGRGEPVRRSAIRRGHRPRGSL 1041
SS P +D+ + + R G RP+ S+
Sbjct: 1005 RTSSRAPCSPTSVSDVD-SDALSRGNFEVGFRPQRSV 1040
Score = 35.8 bits (81), Expect = 0.33
Identities = 55/242 (22%), Positives = 77/242 (31%), Gaps = 30/242 (12%)
Query: 1069 EATGAGRLGSRRKPAAPPPSPAAREEQSRSSASSQKGPQALTRSNSLSTPRPTRASRLRR 1128
E G G RR P P P + + +GP+A LSTP S R
Sbjct: 217 ERPAPGNAGPRRPPGDPSTDPEVLPTPEGPESETSRGPRASPTKALLSTPVRNGESHSRE 276
Query: 1129 ARLGDASDTEAADGERGSLGNPEPVGRPAAEQAKKLSRL------DILAMPRKRAGSFTG 1182
G D E GE + + + R + + RL L +P R S
Sbjct: 277 GLAGLVLDAERTLGEL----DRDALRRSRLRKVQTFPRLLSDSPEATLCLPLTRGKSQLP 332
Query: 1183 TSDPEAAPARTSFSGRSVELCCASRKPTM-------AEARAVSRKAANTATTTGPRQPFS 1235
S+ + R +F R L +P E + A +T GP P S
Sbjct: 333 ISELFSPDPRKAFLDRKNGLSSFQAQPKCRLWPEQEPEHQLGRVPCAGRSTDRGPGVPGS 392
Query: 1236 RARSGSARYTSTTQTPRAGSSSRARSRAPG-PRDTDDDEEEPDPYGFIVQTAEIAEIARL 1294
+ P S+ + AP PRD + + P I + A E A
Sbjct: 393 PGQ------------PETSHPSQGPAEAPADPRDASGEAQTPRDDERIPEGARQLESAAA 440
Query: 1295 SQ 1296
Q
Sbjct: 441 EQ 442
>gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]
Length = 1073
Score = 54.3 bits (129), Expect = 9e-07
Identities = 144/608 (23%), Positives = 197/608 (32%), Gaps = 85/608 (13%)
Query: 593 GVLESPELSRASSATFRPVIRGDRDESDDGGVAQRMALLQEFASRPLGAAPQAEHQGLPV 652
G + +P S + P +RG + DG ++ A +E + P+G GLP
Sbjct: 404 GHVGAPGPSGPPGSVGAPGLRGTPGK--DGERGEKGAAGEEGSPGPVGPRGDPGAPGLPG 461
Query: 653 P------------GSPG--------GQKWVSRWASLADSYSDPGLTEDGLGRRGGEPEGS 692
P GSPG G + S DPG+ G G P G
Sbjct: 462 PPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPP-GD 520
Query: 693 LPVRMRRRLPQLPSERADSPAGPES-SRRSGPGPPELDSEQPSRLFGQEELDPDSLSDAS 751
R LP P + PAG + S PG L L D +D
Sbjct: 521 KGSPGSRGLPGFPGPQG--PAGRDGLSSLLSPGDINL-------------LAKDVCNDCP 565
Query: 752 GSDGGRGPEPGVEPQDSRRRSP-QEGPTWSRGRRSPRAPGEPTPASFF-----IGDQNGD 805
G PG + P +EG +G P PG P P G++ D
Sbjct: 566 PGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGP--PGLPGPPGIAGPQGSQGERGAD 623
Query: 806 AVLSRK-PLAAPGDGEGLGQTAQPSPPARDGVYVSANGRMVIQLRPGRS--PEPDGPA-- 860
+ +K PG +G P PP DG+ A G IQ PG+ P P GP+
Sbjct: 624 GEVGQKGDQGHPGVPGFMGPPGNPGPPGADGI-AGAAGPPGIQGSPGKEGPPGPQGPSGL 682
Query: 861 PAFLRQESFTKEPASGPPAPGKPPHISSHPLLQDLAATRA-ARMDFHSQDTHLILKETET 919
P +E KE G P P P + P L R H+ D+ E+
Sbjct: 683 PGIPGEEG--KEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGES 740
Query: 920 ALAALEAR--LLSNSVDAECEGGSTPRPPEDALSGDSDVDTASTVSLRSGKSGPSPTTPQ 977
L + L D G P+ P + + G+ GPS T Q
Sbjct: 741 GAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGS-------PGEPGPSGTPGQ 793
Query: 978 PLRAQKEMSPSPPAAQDPGGTALVSAREQSSERQHHPLGPTDMG----RGEPVRRSAIRR 1033
+ SP P P G + ++ P P + G RG+P I+
Sbjct: 794 KGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDP----GIKG 849
Query: 1034 GHRPRGSLDWPSEERGPVLAHLPSSDVMASNHETPEATGAGRLGSRRKPAAP---PPSPA 1090
P G P + P H + +M E G G +P P SP+
Sbjct: 850 DKGPPGGKGQPGDPGIP--GHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPS 907
Query: 1091 AREEQSRSSASSQKGPQALTRSNSLSTPRPTRASRLRRARLGDAS--DTEAADGERGSLG 1148
E R + G Q TR L P + + R G + G G +G
Sbjct: 908 M--ETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMG 965
Query: 1149 NPEPVGRP 1156
P GRP
Sbjct: 966 EP---GRP 970
Score = 45.8 bits (107), Expect = 3e-04
Identities = 134/582 (23%), Positives = 170/582 (29%), Gaps = 125/582 (21%)
Query: 610 PVIRGDRDESDDGGVAQRMALLQEFASRPLGAAPQAEHQGLPVPGSPGGQKWVSRWASLA 669
P ++GDR E + G A L P + H +P P G+K
Sbjct: 312 PGLKGDRGEKGEAGPAGPPGL-------PGTTSLFTPHPRMPGEQGPKGEK--------- 355
Query: 670 DSYSDPGLT-EDGLGRRGGE-----PEGSLPVRMRRRLPQLPSERADSPAGPESSRRSGP 723
DPGL E GL R GE P G + + P A +P P GP
Sbjct: 356 ---GDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGA-AGNPGAPGHVGAPGP 411
Query: 724 -GPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQEGPTWSRG 782
GPP + L G DG RG E G ++ SP GP RG
Sbjct: 412 SGPPG-------------SVGAPGLRGTPGKDGERG-EKGAAGEEG---SP--GPVGPRG 452
Query: 783 RRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSANG 842
P APG P P ++G+ L P PG G P P
Sbjct: 453 --DPGAPGLPGPPG---KGKDGEPGLRGSP-GLPGPLGTKGDRGAPGIPGS--------- 497
Query: 843 RMVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSHPLLQDLAATRAAR 902
PG +P +GPP P PP P + L
Sbjct: 498 -------PGSRGDPG--------------IGVAGPPGPSGPPGDKGSPGSRGLPG----- 531
Query: 903 MDFHSQDTHLILKETETALAALEARLLSNSVDAECEGGSTPRPPEDALSGDSDVDTASTV 962
F + L+ + LL+ V +C G P GD V
Sbjct: 532 --FPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVP----- 584
Query: 963 SLRSGKSGPSPTTPQPLRAQKEMSPSPPAAQDPGGTALVSAREQSSER---QHHPLGPTD 1019
GK G T + A P PP P G+ + + Q HP P
Sbjct: 585 ----GKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGF 640
Query: 1020 MG---RGEPVRRSAIRRGHRPRGSLDWPSEERGPVLAHLPSSDVMASNHETPEATGA--- 1073
MG P I P G P +E GP PS E E
Sbjct: 641 MGPPGNPGPPGADGIAGAAGPPGIQGSPGKE-GPPGPQGPSGLPGIPGEEGKEGRDGKPG 699
Query: 1074 --GRLGSRRKPAAPPPSPAAREEQSRSSASSQKGPQALTRSNSLSTPRPTRASRLRRARL 1131
G G +P P P A + P S ++ P +
Sbjct: 700 PPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLP----GKD 755
Query: 1132 GDASDT-----------EAADGERGSLGNPEPVGRPAAEQAK 1162
GD T +G GS G P P G P + +K
Sbjct: 756 GDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSK 797
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.129 0.375
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 76,906,492
Number of Sequences: 37866
Number of extensions: 4901611
Number of successful extensions: 38623
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 142
Number of HSP's successfully gapped in prelim test: 1531
Number of HSP's that attempted gapping in prelim test: 25290
Number of HSP's gapped (non-prelim): 12648
length of query: 1554
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1438
effective length of database: 13,855,062
effective search space: 19923579156
effective search space used: 19923579156
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.