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Search of human proteins with 163310749
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|163310749 LIM and calponin homology domains 1 isoform e
[Homo sapiens]
(890 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|163310749 LIM and calponin homology domains 1 isoform e [Homo... 1790 0.0
gi|163310747 LIM and calponin homology domains 1 isoform d [Homo... 1781 0.0
gi|163310745 LIM and calponin homology domains 1 isoform c [Homo... 1768 0.0
gi|163310743 LIM and calponin homology domains 1 isoform b [Homo... 1764 0.0
gi|163310741 LIM and calponin homology domains 1 isoform a [Homo... 1749 0.0
gi|33598968 LIM domain only 7 isoform 1 [Homo sapiens] 289 7e-78
gi|221316634 LIM domain only 7 isoform 2 [Homo sapiens] 168 2e-41
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 59 2e-08
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 59 3e-08
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 59 3e-08
gi|4505101 microtubule-associated protein 7 [Homo sapiens] 56 1e-07
gi|238908501 sciellin isoform 3 [Homo sapiens] 55 4e-07
gi|238908499 sciellin isoform 1 [Homo sapiens] 55 4e-07
gi|238908497 sciellin isoform 2 [Homo sapiens] 55 4e-07
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 54 6e-07
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 54 8e-07
gi|22758136 MAP7 domain containing 2 [Homo sapiens] 53 1e-06
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 52 3e-06
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 49 2e-05
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 49 2e-05
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 49 2e-05
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 49 2e-05
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 49 2e-05
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 49 2e-05
gi|221219020 NYD-SP11 protein [Homo sapiens] 49 2e-05
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 49 3e-05
gi|15149467 caldesmon 1 isoform 3 [Homo sapiens] 49 3e-05
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 48 4e-05
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 48 5e-05
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 48 5e-05
>gi|163310749 LIM and calponin homology domains 1 isoform e [Homo
sapiens]
Length = 890
Score = 1790 bits (4637), Expect = 0.0
Identities = 890/890 (100%), Positives = 890/890 (100%)
Query: 1 MDSERQVKDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQ 60
MDSERQVKDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQ
Sbjct: 1 MDSERQVKDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQ 60
Query: 61 TPSPDVVLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKS 120
TPSPDVVLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKS
Sbjct: 61 TPSPDVVLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKS 120
Query: 121 NQTAYVPAPLRKKKAEREEYRKSWSTATSPLGGERPFRSTSMFDMRCEEEAAVQPHSRAR 180
NQTAYVPAPLRKKKAEREEYRKSWSTATSPLGGERPFRSTSMFDMRCEEEAAVQPHSRAR
Sbjct: 121 NQTAYVPAPLRKKKAEREEYRKSWSTATSPLGGERPFRSTSMFDMRCEEEAAVQPHSRAR 180
Query: 181 QEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERR 240
QEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERR
Sbjct: 181 QEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERR 240
Query: 241 KSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLEMPKIL 300
KSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLEMPKIL
Sbjct: 241 KSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLEMPKIL 300
Query: 301 ERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSK 360
ERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSK
Sbjct: 301 ERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSK 360
Query: 361 TVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVAPAHSL 420
TVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVAPAHSL
Sbjct: 361 TVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVAPAHSL 420
Query: 421 TKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKNDGGK 480
TKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKNDGGK
Sbjct: 421 TKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKNDGGK 480
Query: 481 SRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEMSGKVE 540
SRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEMSGKVE
Sbjct: 481 SRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEMSGKVE 540
Query: 541 LVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTPFKFWA 600
LVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTPFKFWA
Sbjct: 541 LVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTPFKFWA 600
Query: 601 WDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIED 660
WDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIED
Sbjct: 601 WDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIED 660
Query: 661 TVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKT 720
TVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKT
Sbjct: 661 TVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKT 720
Query: 721 RESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTS 780
RESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTS
Sbjct: 721 RESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTS 780
Query: 781 NPTHSSEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSCGLPLGKGAAMIIETLNL 840
NPTHSSEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSCGLPLGKGAAMIIETLNL
Sbjct: 781 NPTHSSEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSCGLPLGKGAAMIIETLNL 840
Query: 841 YFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL 890
YFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL
Sbjct: 841 YFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL 890
>gi|163310747 LIM and calponin homology domains 1 isoform d [Homo
sapiens]
Length = 902
Score = 1781 bits (4614), Expect = 0.0
Identities = 890/902 (98%), Positives = 890/902 (98%), Gaps = 12/902 (1%)
Query: 1 MDSERQVKDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQ 60
MDSERQVKDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQ
Sbjct: 1 MDSERQVKDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQ 60
Query: 61 TPSPDVVLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKS 120
TPSPDVVLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKS
Sbjct: 61 TPSPDVVLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKS 120
Query: 121 NQTAYVPAPLRKKKAEREEYRKSWSTATSPLGGERPFR------------STSMFDMRCE 168
NQTAYVPAPLRKKKAEREEYRKSWSTATSPLGGERPFR STSMFDMRCE
Sbjct: 121 NQTAYVPAPLRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCE 180
Query: 169 EEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEK 228
EEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEK
Sbjct: 181 EEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEK 240
Query: 229 LLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISE 288
LLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISE
Sbjct: 241 LLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISE 300
Query: 289 AVLERLEMPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLD 348
AVLERLEMPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLD
Sbjct: 301 AVLERLEMPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLD 360
Query: 349 TSMSAGSGSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKE 408
TSMSAGSGSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKE
Sbjct: 361 TSMSAGSGSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKE 420
Query: 409 RECPTVAPAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTE 468
RECPTVAPAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTE
Sbjct: 421 RECPTVAPAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTE 480
Query: 469 PNSQEDKNDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQ 528
PNSQEDKNDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQ
Sbjct: 481 PNSQEDKNDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQ 540
Query: 529 KKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSE 588
KKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSE
Sbjct: 541 KKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSE 600
Query: 589 KSPVMTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEER 648
KSPVMTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEER
Sbjct: 601 KSPVMTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEER 660
Query: 649 RYYEEERKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKS 708
RYYEEERKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKS
Sbjct: 661 RYYEEERKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKS 720
Query: 709 FQGDDSDLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQ 768
FQGDDSDLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQ
Sbjct: 721 FQGDDSDLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQ 780
Query: 769 LAQDPSQNQQTSNPTHSSEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSCGLPLG 828
LAQDPSQNQQTSNPTHSSEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSCGLPLG
Sbjct: 781 LAQDPSQNQQTSNPTHSSEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSCGLPLG 840
Query: 829 KGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPT 888
KGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPT
Sbjct: 841 KGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPT 900
Query: 889 TL 890
TL
Sbjct: 901 TL 902
>gi|163310745 LIM and calponin homology domains 1 isoform c [Homo
sapiens]
Length = 1056
Score = 1768 bits (4580), Expect = 0.0
Identities = 883/895 (98%), Positives = 883/895 (98%), Gaps = 12/895 (1%)
Query: 8 KDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVV 67
KDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVV
Sbjct: 162 KDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVV 221
Query: 68 LRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVP 127
LRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVP
Sbjct: 222 LRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVP 281
Query: 128 APLRKKKAEREEYRKSWSTATSPLGGERPFR------------STSMFDMRCEEEAAVQP 175
APLRKKKAEREEYRKSWSTATSPLGGERPFR STSMFDMRCEEEAAVQP
Sbjct: 282 APLRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQP 341
Query: 176 HSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDG 235
HSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDG
Sbjct: 342 HSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDG 401
Query: 236 TSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLE 295
TSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLE
Sbjct: 402 TSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLE 461
Query: 296 MPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGS 355
MPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGS
Sbjct: 462 MPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGS 521
Query: 356 GSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVA 415
GSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVA
Sbjct: 522 GSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVA 581
Query: 416 PAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDK 475
PAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDK
Sbjct: 582 PAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDK 641
Query: 476 NDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEM 535
NDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEM
Sbjct: 642 NDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEM 701
Query: 536 SGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTP 595
SGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTP
Sbjct: 702 SGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTP 761
Query: 596 FKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEER 655
FKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEER
Sbjct: 762 FKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEER 821
Query: 656 KIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSD 715
KIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSD
Sbjct: 822 KIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSD 881
Query: 716 LLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQ 775
LLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQ
Sbjct: 882 LLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQ 941
Query: 776 NQQTSNPTHSSEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSCGLPLGKGAAMII 835
NQQTSNPTHSSEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSCGLPLGKGAAMII
Sbjct: 942 NQQTSNPTHSSEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSCGLPLGKGAAMII 1001
Query: 836 ETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL 890
ETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL
Sbjct: 1002 ETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL 1056
>gi|163310743 LIM and calponin homology domains 1 isoform b [Homo
sapiens]
Length = 1057
Score = 1764 bits (4568), Expect = 0.0
Identities = 883/896 (98%), Positives = 883/896 (98%), Gaps = 13/896 (1%)
Query: 8 KDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVV 67
KDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVV
Sbjct: 162 KDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVV 221
Query: 68 LRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVP 127
LRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVP
Sbjct: 222 LRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVP 281
Query: 128 APLRKKKAEREEYRKSWSTATSPLGGERPFR------------STSMFDMRCEEEAAVQP 175
APLRKKKAEREEYRKSWSTATSPLGGERPFR STSMFDMRCEEEAAVQP
Sbjct: 282 APLRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQP 341
Query: 176 HSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDG 235
HSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDG
Sbjct: 342 HSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDG 401
Query: 236 TSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLE 295
TSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLE
Sbjct: 402 TSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLE 461
Query: 296 MPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGS 355
MPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGS
Sbjct: 462 MPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGS 521
Query: 356 GSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVA 415
GSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVA
Sbjct: 522 GSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVA 581
Query: 416 PAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDK 475
PAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDK
Sbjct: 582 PAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDK 641
Query: 476 NDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEM 535
NDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEM
Sbjct: 642 NDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEM 701
Query: 536 SGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTP 595
SGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTP
Sbjct: 702 SGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTP 761
Query: 596 -FKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEE 654
FKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEE
Sbjct: 762 QFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEE 821
Query: 655 RKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDS 714
RKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDS
Sbjct: 822 RKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDS 881
Query: 715 DLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPS 774
DLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPS
Sbjct: 882 DLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPS 941
Query: 775 QNQQTSNPTHSSEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSCGLPLGKGAAMI 834
QNQQTSNPTHSSEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSCGLPLGKGAAMI
Sbjct: 942 QNQQTSNPTHSSEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSCGLPLGKGAAMI 1001
Query: 835 IETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL 890
IETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL
Sbjct: 1002 IETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL 1057
>gi|163310741 LIM and calponin homology domains 1 isoform a [Homo
sapiens]
Length = 1083
Score = 1749 bits (4531), Expect = 0.0
Identities = 883/922 (95%), Positives = 883/922 (95%), Gaps = 39/922 (4%)
Query: 8 KDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVV 67
KDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVV
Sbjct: 162 KDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVV 221
Query: 68 LRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVP 127
LRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVP
Sbjct: 222 LRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVP 281
Query: 128 APLRKKKAEREEYRKSWSTATSPLGGERPFR------------STSMFDMRCEEEAAVQP 175
APLRKKKAEREEYRKSWSTATSPLGGERPFR STSMFDMRCEEEAAVQP
Sbjct: 282 APLRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQP 341
Query: 176 HSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDG 235
HSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDG
Sbjct: 342 HSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDG 401
Query: 236 TSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLE 295
TSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLE
Sbjct: 402 TSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLE 461
Query: 296 MPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGS 355
MPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGS
Sbjct: 462 MPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGS 521
Query: 356 GSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVA 415
GSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVA
Sbjct: 522 GSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVA 581
Query: 416 PAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDK 475
PAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDK
Sbjct: 582 PAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDK 641
Query: 476 NDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEM 535
NDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEM
Sbjct: 642 NDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEM 701
Query: 536 SGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTP 595
SGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTP
Sbjct: 702 SGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTP 761
Query: 596 -FKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEE 654
FKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEE
Sbjct: 762 QFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEE 821
Query: 655 RKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDS 714
RKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDS
Sbjct: 822 RKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDS 881
Query: 715 DLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPS 774
DLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPS
Sbjct: 882 DLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPS 941
Query: 775 QNQQTSNPTHSSEDVKPKTLPLDKSINHQIESPSERRK---------------------- 812
QNQQTSNPTHSSEDVKPKTLPLDKSINHQIESPSERRK
Sbjct: 942 QNQQTSNPTHSSEDVKPKTLPLDKSINHQIESPSERRKKSPREHFQAGPFSPCSPTPPGQ 1001
Query: 813 ----SISGKKLCSSCGLPLGKGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIR 868
SISGKKLCSSCGLPLGKGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIR
Sbjct: 1002 SPNRSISGKKLCSSCGLPLGKGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIR 1061
Query: 869 NGLLNCNDCYMRSRSAGQPTTL 890
NGLLNCNDCYMRSRSAGQPTTL
Sbjct: 1062 NGLLNCNDCYMRSRSAGQPTTL 1083
>gi|33598968 LIM domain only 7 isoform 1 [Homo sapiens]
Length = 1349
Score = 289 bits (740), Expect = 7e-78
Identities = 251/852 (29%), Positives = 404/852 (47%), Gaps = 155/852 (18%)
Query: 8 KDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHG-RDDSFDSLDSFGSRSRQTPSPDV 66
K +D KRS RDSGY D W ER + L+PPRH R+DSF+SLDS GSRS + S D+
Sbjct: 206 KALEDSSFLKRSGRDSGYGDIWCPERGEFLAPPRHHKREDSFESLDSLGSRSLTSCSSDI 265
Query: 67 VLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYV 126
LRG +G SD++S+ K+ D KDDMS RR S EPK+A+PFN++LPNKS Q +YV
Sbjct: 266 TLRGGREGFESDTDSEFTF-KMQDYNKDDMSYRRISAVEPKTALPFNRFLPNKSRQPSYV 324
Query: 127 PAPLRKKKAER-EEYRKSWSTATSPLGGE------RPFR-------STSMFDMRCEEEAA 172
PAPLRKKK ++ E+ R+SW+ SP+ E R F+ S SM D+ E+
Sbjct: 325 PAPLRKKKPDKHEDNRRSWA---SPVYTEADGTFSRLFQKIYGENGSKSMSDVSAED--- 378
Query: 173 VQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAG 232
VQ + R E++Q I +QL+E+D KWQDDLA+WK RR+S + DL KK+EER+++EK
Sbjct: 379 VQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEK---- 434
Query: 233 EDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQ--YIERFTISEAV 290
+ ++S KT++E++Q++E + ++ + R + +L++ T+SEA
Sbjct: 435 -QALEKSKRSSKTFKEMLQDRESQNQK--STVPSRRRMYSFDDVLEEGKRPPTMTVSEAS 491
Query: 291 L--ERLEMPKILERSHSTEPNLSSFLNDPNPMK---YLRQQSLPPPKFTATVETTIARAS 345
ER+E S + + ++F + + L QS + A++ + +R++
Sbjct: 492 YQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRST 551
Query: 346 VLDTSMSAGS--GSPSKTVTPKAVPMLTPKPY-SQPKNSQDVLKTFKVDGKVSVNG---- 398
++++ + S S KT T + ++TP+P+ SQ + + +++ +D NG
Sbjct: 552 QMESTRVSASLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTMDDAWKYNGDVED 611
Query: 399 -----------------------------ETVHREEEKERECPTVAPAHSLTKSQMFEGV 429
E EE+ R +P SL++ Q
Sbjct: 612 IKRTPNNVVSTPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTSPFSSLSQDQAATSK 671
Query: 430 ARVHG-SPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIEL 488
A + S L+L ++G EI S +E++ + ++ GKS +
Sbjct: 672 ATLSSTSGLDLMSESGEGEI------SPQREVSRSQDQFSDMRISINQTPGKSLDFGFTI 725
Query: 489 ASSEPQHFTTTVTRCSPTVAFVEFPSSPQ---LKNDVSEEKDQKKPENEMSGKVE---LV 542
P F +V SP F + + + N D K+ E M+ E LV
Sbjct: 726 KWDIPGIFVASVEAGSP-AEFSQLQVDDEIIAINNTKFSYNDSKEWEEAMAKAQETGHLV 784
Query: 543 LS-QKVVKPKSPEPE----------------ATLTFPFLDKMPEAN-------------- 571
+ ++ K SPE + ++T F + + +N
Sbjct: 785 MDVRRYGKAGSPETKWIDATSGIYNSEKSSNLSVTTDFSESLQSSNIESKEINGIHDESN 844
Query: 572 --------QLHLPNL--NSQVDSPSSEKS-------PVMTPFKFWAWDPEEERRRQEKWQ 614
+ L NL SQ S S P ++ W WD EEER+RQE+WQ
Sbjct: 845 AFESKASESISLKNLKRRSQFFEQGSSDSVVPDLPVPTISAPSRWVWDQEEERKRQERWQ 904
Query: 615 QEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTV------- 667
+EQ+RLLQE+YQ+EQ+KL+EEW++A++E E E +Y +EE ++ + T
Sbjct: 905 KEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLAT 964
Query: 668 -------SSSSADQLSTSSSMTEGSGTMNKI---DLG-NCQDE---KQDRRWKKSFQGDD 713
S S+D+ T + E ++ D G QD+ +++R+W++ Q +
Sbjct: 965 WEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQ 1024
Query: 714 SDLLLKTRESDR 725
L+ ++
Sbjct: 1025 EQKRLQAEAEEQ 1036
Score = 113 bits (282), Expect = 9e-25
Identities = 101/343 (29%), Positives = 160/343 (46%), Gaps = 60/343 (17%)
Query: 604 EEERRRQEKWQQEQERLLQERYQKEQDKLKE--EWEKAQKEVEEEERRYYEEERKIIEDT 661
E ER+ +++ Q+EQE Q+R Q E ++ K E +K Q E+E E + R+ ++
Sbjct: 1011 ERERKWEQQLQEEQE---QKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSY 1067
Query: 662 VVPFTVSSSS----ADQLSTSSS------MTEGSGTMNKID-LGNC-------------- 696
+P T +SS D+ + S+ T +G +D +GN
Sbjct: 1068 DIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPS 1127
Query: 697 ------QDEKQDRRWKKSFQGDDSDLLLKTRESDR--LEEKGSLTEG-ALAHSGNPVSKG 747
Q Q+ R + D+S + ++ ++ + G + G +L + +P S
Sbjct: 1128 GAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLDNLDSPRSNS 1187
Query: 748 VHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSN-----------PTHSSEDVKPKT--L 794
+ L+ G + ++ P Q TSN P S+ VK T +
Sbjct: 1188 WRQPPWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNPSSSVPPPSAGSVKTSTTGV 1247
Query: 795 PLDKSINHQIESPSE-------RRKSISGKKLCSSCGLPLGKGAAMIIETLNLYFHIQCF 847
+S + SPS R +S+SGK++CS C LGKGAAMIIE+L L +H+ CF
Sbjct: 1248 ATTQSPTPRSHSPSASQSGSQLRNRSVSGKRICSYCNNILGKGAAMIIESLGLCYHLHCF 1307
Query: 848 RCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL 890
+C C+ LG + SG +VRIRN L CNDCY+R +S G+PT +
Sbjct: 1308 KCVACECDLGGSSSGAEVRIRNHQLYCNDCYLRFKS-GRPTAM 1349
>gi|221316634 LIM domain only 7 isoform 2 [Homo sapiens]
Length = 1385
Score = 168 bits (426), Expect = 2e-41
Identities = 188/760 (24%), Positives = 327/760 (43%), Gaps = 151/760 (19%)
Query: 92 KKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAEREEYRKSWSTATSPL 151
KKDDM R+ + + VP + P ++ A L++ +A RE R L
Sbjct: 351 KKDDMLTRKIQSWKLGTTVPPISFTPGPCSE-----ADLKRWEAIREASRLRHKKR---L 402
Query: 152 GGERPFR-------STSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLAR 204
ER F+ S SM D+ E+ VQ + R E++Q I +QL+E+D KWQDDLA+
Sbjct: 403 MVERLFQKIYGENGSKSMSDVSAED---VQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAK 459
Query: 205 WKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAY 264
WK RR+S + DL KK+EER+++EK + ++S KT++E++Q++E + ++
Sbjct: 460 WKDRRKSYTSDLQKKKEEREEIEK-----QALEKSKRSSKTFKEMLQDRESQNQK--STV 512
Query: 265 KNARSQEEAEGILQQ--YIERFTISEAVL--ERLEMPKILERSHSTEPNLSSFLNDPNPM 320
+ R + +L++ T+SEA ER+E S + + ++F + +
Sbjct: 513 PSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRV 572
Query: 321 K---YLRQQSLPPPKFTATVETTIARASVLDTSMSAGS--GSPSKTVTPKAVPMLTPKPY 375
L QS + A++ + +R++ ++++ + S S KT T + ++TP+P+
Sbjct: 573 TTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTRVSASLPRSYRKTDTVRLTSVVTPRPF 632
Query: 376 -SQPKNSQDVLKTFKVDGKVSVNG---------------------------------ETV 401
SQ + + +++ +D NG E
Sbjct: 633 GSQTRGISSLPRSYTMDDAWKYNGDVEDIKRTPNNVVSTPAPSPDASQLASSLSSQKEVA 692
Query: 402 HREEEKERECPTVAPAHSLTKSQMFEGVARVHG-SPLELKQDNGSIEINIKKPNSVPQEL 460
EE+ R +P SL++ Q A + S L+L ++G EI S +E+
Sbjct: 693 ATEEDVTRLPSPTSPFSSLSQDQAATSKATLSSTSGLDLMSESGEGEI------SPQREV 746
Query: 461 AATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQ--- 517
+ + ++ GKS + P F +V SP F + +
Sbjct: 747 SRSQDQFSDMRISINQTPGKSLDFGFTIKWDIPGIFVASVEAGSP-AEFSQLQVDDEIIA 805
Query: 518 LKNDVSEEKDQKKPENEMSGKVE---LVLS-QKVVKPKSPEPE----------------A 557
+ N D K+ E M+ E LV+ ++ K SPE +
Sbjct: 806 INNTKFSYNDSKEWEEAMAKAQETGHLVMDVRRYGKAGSPETKWIDATSGIYNSEKSSNL 865
Query: 558 TLTFPFLDKMPEAN----------------------QLHLPNL--NSQVDSPSSEKS--- 590
++T F + + +N + L NL SQ S S
Sbjct: 866 SVTTDFSESLQSSNIESKEINGIHDESNAFESKASESISLKNLKRRSQFFEQGSSDSVVP 925
Query: 591 ----PVMTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEE 646
P ++ W WD EEER+RQE+WQ+EQ+RLLQE+YQ+EQ+KL+EEW++A++E E E
Sbjct: 926 DLPVPTISAPSRWVWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERE 985
Query: 647 ERRYYEEERKIIEDTVVPFTV--------------SSSSADQLSTSSSMTEGSGTMNKI- 691
+Y +EE ++ + T S S+D+ T + E ++
Sbjct: 986 NSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVV 1045
Query: 692 --DLG-NCQDE---KQDRRWKKSFQGDDSDLLLKTRESDR 725
D G QD+ +++R+W++ Q + L+ ++
Sbjct: 1046 HEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQ 1085
Score = 77.0 bits (188), Expect = 7e-14
Identities = 36/60 (60%), Positives = 48/60 (80%), Gaps = 1/60 (1%)
Query: 88 LPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAER-EEYRKSWST 146
+ D KDDMS RR S EPK+A+PFN++LPNKS Q +YVPAPLRKKK ++ E+ R+SW++
Sbjct: 1 MQDYNKDDMSYRRISAVEPKTALPFNRFLPNKSRQPSYVPAPLRKKKPDKHEDNRRSWAS 60
Score = 38.1 bits (87), Expect = 0.037
Identities = 18/54 (33%), Positives = 37/54 (68%)
Query: 603 PEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERK 656
P+EE +++ ++ Q++L+ ER +K + +L+EE E+ + + E EE++ EE+K
Sbjct: 1040 PQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQK 1093
Score = 36.2 bits (82), Expect = 0.14
Identities = 26/96 (27%), Positives = 43/96 (44%), Gaps = 10/96 (10%)
Query: 53 SFGSRSRQTPSPDV----VLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKS 108
+F S R+ +V ++G+S E R +P++ KDD+ R+ S P
Sbjct: 69 TFSSNQRRIWGTNVENWPTVQGTSKSSCYLEEEKAKTRSIPNIVKDDLYVRKLSPVMPNP 128
Query: 109 AVPFNQYLPNKSNQTAYVPAPLRKKKAEREEYRKSW 144
F+Q+LP + P + K+ +RE Y K W
Sbjct: 129 GNAFDQFLPK-----CWTPEDVNWKRIKRETY-KPW 158
Score = 35.0 bits (79), Expect = 0.31
Identities = 23/70 (32%), Positives = 39/70 (55%), Gaps = 5/70 (7%)
Query: 604 EEERRRQEKWQQEQERLLQERYQKEQDKLKE--EWEKAQKEVEEEERRYYEEERKIIEDT 661
E ER+ +++ Q+EQE Q+R Q E ++ K E +K Q E+E E + R+ ++
Sbjct: 1060 ERERKWEQQLQEEQE---QKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSY 1116
Query: 662 VVPFTVSSSS 671
+P T +SS
Sbjct: 1117 DIPKTEEASS 1126
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 59.3 bits (142), Expect = 2e-08
Identities = 155/784 (19%), Positives = 310/784 (39%), Gaps = 135/784 (17%)
Query: 4 ERQVKDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPS 63
E+ +T+D E ++++RD DSE LS D S SL G ++TPS
Sbjct: 437 EQAALETEDGEGLQQTLRDLAQAVLSDSESGVQLSGSERTADASNGSLR--GLSGQRTPS 494
Query: 64 PDVVLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQT 123
P R SS GRG R+ P A + S+
Sbjct: 495 PP---RRSSPGRG-----------------------RSPRRGPSPAC-------SDSSTL 521
Query: 124 AYVPAPLRKKKAEREEYRKSWSTATSPLGGERPFRSTSMFDMRCEEE----------AAV 173
A + + L K++ + ++ R + + LG R S S + R EE A+
Sbjct: 522 ALIHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAM 581
Query: 174 QPHSRARQE--QLQLINNQLREEDD---------KWQDDLARWKSRRRSVSQDLIKKEEE 222
Q H A++E +L+ N L E + Q + R + + +Q+ ++++ +
Sbjct: 582 QAHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRD 641
Query: 223 RKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRE------RELHEAYKNARSQEEAEGI 276
R + E+ A +DG RR+ +++R++ Q + +R E+ EA A Q + +
Sbjct: 642 RLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRD---M 698
Query: 277 LQQYIERFTISEAVLE----RLEMPKILERSHSTEPNLSSFLNDPNPM-KYLRQQSLPPP 331
LQ E+ ++EA+ + R+E+ + + + E +L L+ + + + L Q L
Sbjct: 699 LQ--AEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLN 756
Query: 332 KFTATVETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVD 391
+ A L+ SA G + V + + + Q+V + ++
Sbjct: 757 RLVAQ----------LEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQ-GLE 805
Query: 392 GKVSVNGETVHREEEKERECPTVAPAHSLTKSQMFEGVARVHGSPLELKQDN-------G 444
G + V + +E E++ PT+ S + Q+ + ++ G EL+Q
Sbjct: 806 GSLRVAEQA---QEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVE 862
Query: 445 SIEINIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQHFTTTVTRCS 504
++E ++ ++ +E A + +E + ++ + +E + E F
Sbjct: 863 ALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQ 922
Query: 505 PTVAFVEFPSSPQ--------LKNDVSEEKDQKKPENEMSGKVELVLSQKVVKPKSPEPE 556
+ + Q L +++ + Q E + + +++QK+V+ + E +
Sbjct: 923 LEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAER-EAQ 981
Query: 557 ATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTPFKFWAWDPEEERRRQEKWQQE 616
A+L + A++ L L + ++ W E + Q + Q+E
Sbjct: 982 ASLR-----EQRAAHEEDLQRLQREKEAA-------------WRELEAERAQLQSQLQRE 1023
Query: 617 QERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSADQLS 676
QE LL R + E+++L EE Q+E +E ++ ++ +S +++ +
Sbjct: 1024 QEELL-ARLEAEKEELSEEIAALQQE---------RDEGLLLAESEKQQALSLKESEKTA 1073
Query: 677 TSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESDRLEEKGSLTEGA 736
S + GT + + + + E+Q R + + D S + T E L + E A
Sbjct: 1074 LSEKL---MGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDL--RAQREEAA 1128
Query: 737 LAHS 740
AH+
Sbjct: 1129 AAHA 1132
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 58.5 bits (140), Expect = 3e-08
Identities = 99/526 (18%), Positives = 209/526 (39%), Gaps = 57/526 (10%)
Query: 166 RCEEEAAVQPHS-RARQEQLQLINNQLREEDDKWQDD---LARWKSRRRSVSQDLIKKEE 221
R EEE Q R ++E++ +LRE++ K ++ + R + R R ++L ++E+
Sbjct: 276 RQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEK 335
Query: 222 ERKKMEKLLAGEDGTSERRKSIKTYREIVQEKE----RRERELHEAYKNARSQE------ 271
E ++ ++L E+ E+ + + E ++E+E R+E L E K R QE
Sbjct: 336 ELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQ 395
Query: 272 -----EAEGILQQYIERFTISEAVLERLEMPKILERSHSTEPNLSSFLNDPNPMKYLRQQ 326
E + L++ ER E + E++E + ++ E + +R++
Sbjct: 396 EERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIRER 455
Query: 327 SLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKPYSQPKNSQDVLK 386
K ET + + K + +P K + Q K + K
Sbjct: 456 E---KKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEK 512
Query: 387 TFKVDGKVSVNGETVHRE-----EEKERECPTVAPAHSLTKSQMFEGVARVHGSPLELKQ 441
++ + K+ E +E +EK RE + QM+E ++ ++
Sbjct: 513 IWEQEEKIRDQEEMWGQEKKMWRQEKMRE----------QEDQMWEQEEKMRDQEQKMWD 562
Query: 442 DNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQHFTTTVT 501
+E ++ QE ++ + +E + K + E+ + +
Sbjct: 563 QEERMEKKTQE-----QEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEE 617
Query: 502 RCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTF 561
+ + K EEK Q++ E + ++ ++ + + PE
Sbjct: 618 KMQ----------EQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKL 667
Query: 562 PFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTPFKFWAWDP---EEERRRQEKWQQEQE 618
+KM E ++ + EK K W + EE R +EK +E+E
Sbjct: 668 WEHEKMQEQEKMQEQE-EKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEE 726
Query: 619 RLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVP 664
+++E+ +K Q++ +E+ ++ ++E+ E+E + +E+E K+ E +P
Sbjct: 727 EMMREQEEKMQEQ-EEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLP 771
Score = 45.4 bits (106), Expect = 2e-04
Identities = 38/162 (23%), Positives = 70/162 (43%), Gaps = 20/162 (12%)
Query: 131 RKKKAEREEYRKSWSTATSPLGGERPFRSTSMF----DMRCEEEAAVQPHSRARQEQLQL 186
R +K +E+ +K+W ER +M E+E +Q QEQ +
Sbjct: 566 RMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEK 625
Query: 187 INNQ---LREEDDK--------WQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDG 235
+ Q ++E+++K W+ + W+ +R ++ + + E+ ++ EK+ E+
Sbjct: 626 MWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEK 685
Query: 236 TSERRKSIKTYREIV-----QEKERRERELHEAYKNARSQEE 272
E+ K K +E QEK R E + E K R +EE
Sbjct: 686 IWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEE 727
Score = 44.7 bits (104), Expect = 4e-04
Identities = 35/150 (23%), Positives = 73/150 (48%), Gaps = 14/150 (9%)
Query: 130 LRKKKAE-REEYRKSWSTATSPLGGERPFRSTSMFDMRCEEEAAVQPHSRARQEQLQLIN 188
LR+++ + RE+ K W E+ R E+E Q R ++EQ+Q
Sbjct: 302 LREQEGKMREQEEKMWRQEKRLREQEKELREQ-------EKELREQKELREQEEQMQEQE 354
Query: 189 NQLREEDDKWQDDLAR-WKSRRRSVSQDLIKKEEERK---KMEKLLAGEDGTSERRKSIK 244
++ E+++K ++ + W+ R Q+ +E+E+K + E++ ++ E+ + ++
Sbjct: 355 EKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMR 414
Query: 245 TYREIVQ--EKERRERELHEAYKNARSQEE 272
++ + EK R E+++ E K R QEE
Sbjct: 415 EQEKMWEQVEKMREEKKMQEQEKKTRDQEE 444
Score = 44.3 bits (103), Expect = 5e-04
Identities = 36/185 (19%), Positives = 82/185 (44%), Gaps = 20/185 (10%)
Query: 138 EEYRKSWSTATSPLGGERPFRSTSMFD-----------MRCEEEAAVQPHSRARQEQLQL 186
E+ K W P E+ + M + +R +EE Q RQE+++
Sbjct: 482 EQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMRE 541
Query: 187 INNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTY 246
+Q+ E+++K +D + + + + ++E++ E+ + E+ ER K ++
Sbjct: 542 QEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREE 601
Query: 247 REIVQEKERRERELHEAY---------KNARSQEEAEGILQQYIERFTISEAVLERLEMP 297
E+++E+E + +E E + + QE+ E + +Q + + E + E+ +P
Sbjct: 602 EEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLP 661
Query: 298 KILER 302
+ E+
Sbjct: 662 EQKEK 666
Score = 43.9 bits (102), Expect = 7e-04
Identities = 30/140 (21%), Positives = 66/140 (47%), Gaps = 17/140 (12%)
Query: 601 WDPEEERRRQEK---------WQQEQERLLQERYQKEQDKLKEEWEK--AQKEVEEEERR 649
W+ E++ R QE+ W+Q++ +E +EQ+K+ E+ EK +K+++E+E++
Sbjct: 379 WEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKK 438
Query: 650 YYEEERKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSF 709
++E K+ E+ + +M E M K + E++++ W++
Sbjct: 439 TRDQEEKMQEEE----RIREREKKMREEEETMREQEEKMQKQE--ENMWEQEEKEWQQQR 492
Query: 710 QGDDSDLLLKTRESDRLEEK 729
+ + L + + EEK
Sbjct: 493 LPEQKEKLWEQEKMQEQEEK 512
Score = 43.9 bits (102), Expect = 7e-04
Identities = 44/225 (19%), Positives = 99/225 (44%), Gaps = 21/225 (9%)
Query: 524 EEKDQK-KPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHL------- 575
E++DQ + E +M + + + Q+ K + + T+ +KM E ++
Sbjct: 541 EQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMRE 600
Query: 576 -PNLNSQVDSPSSEKSPVMTPFKFWAWDPEEERRRQEK--WQQEQERLLQERYQKEQDKL 632
+ + + E+ M + W+ EE+ + QE+ W+QE++ QE EQ +L
Sbjct: 601 EEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRL 660
Query: 633 KEEWEK--------AQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSADQLSTSSSMTEG 684
E+ EK Q++++E+E + +E+E+ +E + +++ SM E
Sbjct: 661 PEQKEKLWEHEKMQEQEKMQEQEEKIWEQEK--MEKKTQEQEKKTWDQEKMREEESMRER 718
Query: 685 SGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESDRLEEK 729
M + + + E++ + ++ Q + ++ + + EEK
Sbjct: 719 EKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEK 763
Score = 43.1 bits (100), Expect = 0.001
Identities = 39/140 (27%), Positives = 61/140 (43%), Gaps = 13/140 (9%)
Query: 533 NEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQV--------DS 584
NE K L +K+ +S + E L L + E + LP + + +
Sbjct: 220 NEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEE 279
Query: 585 PSSEKSPVMTPFKFWAWDPEEERRRQEKWQQEQERLL--QERYQKEQDKLKEEWEK---A 639
E+ + + W EE R QE +EQE + QE+ +EQ+K E EK
Sbjct: 280 ELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELRE 339
Query: 640 QKEVEEEERRYYEEERKIIE 659
QKE+ E+E + E+E K+ E
Sbjct: 340 QKELREQEEQMQEQEEKMWE 359
Score = 42.4 bits (98), Expect = 0.002
Identities = 87/523 (16%), Positives = 195/523 (37%), Gaps = 40/523 (7%)
Query: 137 REEYRKSWSTATSPLGGERPFRSTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREEDD 196
RE+ K W E+ R MR +EE + R R+++ ++RE++
Sbjct: 365 REQEEKMWRQEERLWEQEKQMREQEQ-KMRDQEERMWEQDERLREKE-----ERMREQEK 418
Query: 197 KWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERR 256
W+ + + + ++ Q+ +++E K E E+ ER K ++ E ++E+E +
Sbjct: 419 MWEQ-VEKMREEKKMQEQEKKTRDQEEKMQE-----EERIREREKKMREEEETMREQEEK 472
Query: 257 ERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLEMPKILERSHSTEPNLSSFLND 316
++ E +E + L + E+ E + E+ E KI E+ + +
Sbjct: 473 MQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEE--KIWEQEEKIRDQEEMWGQE 530
Query: 317 PNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKPYS 376
+ + + + + + D + K K +
Sbjct: 531 KKMWRQEKMREQEDQMWEQEEKMRDQEQKMWD----------QEERMEKKTQEQEKKTWD 580
Query: 377 QPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVAPAHSLTKSQMFEGVARVHGSP 436
Q + ++ + + + K+ E + +EEK +E + E +
Sbjct: 581 QEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKM 640
Query: 437 LELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKNDGGKS--RKGNIELASSEPQ 494
E ++ E + + +P++ E + QE + + + +E + E +
Sbjct: 641 WEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQE 700
Query: 495 HFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENE--MSGKVELVLSQKVVKPKS 552
T + + E + + ++ E+++K E E M + E + Q+ K
Sbjct: 701 KKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQE---EKM 757
Query: 553 PEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTPFKFWAWDPEEERRRQEK 612
E E + ++PE + + Q E+ M D EE+ R QE+
Sbjct: 758 WEQEEKMWEQ--QRLPEQKEKLWEHEKMQEQEKIWEQEEKMR-------DQEEKMRGQEE 808
Query: 613 WQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEER 655
+ QE ++ + +K + ++ W + +K +EE+ + +EE+
Sbjct: 809 KMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEK 851
Score = 42.4 bits (98), Expect = 0.002
Identities = 34/137 (24%), Positives = 67/137 (48%), Gaps = 23/137 (16%)
Query: 602 DPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVE---EEERRYYEEERKII 658
+ EE R QE+ QEQE E+ Q++++K+ E+ EK Q++ E E+E + +E+E K+
Sbjct: 600 EEEEMMREQEEKMQEQE----EKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMW 655
Query: 659 EDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRW-KKSFQGDDSDLL 717
E +P ++L M E E++++ W ++ + +
Sbjct: 656 EQQRLP-----EQKEKLWEHEKMQEQEK----------MQEQEEKIWEQEKMEKKTQEQE 700
Query: 718 LKTRESDRLEEKGSLTE 734
KT + +++ E+ S+ E
Sbjct: 701 KKTWDQEKMREEESMRE 717
Score = 39.7 bits (91), Expect = 0.013
Identities = 41/148 (27%), Positives = 69/148 (46%), Gaps = 23/148 (15%)
Query: 525 EKDQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDS 584
E +K P E S K E+ L+ K +K K + FL + N L + +
Sbjct: 229 ELQEKLPLAE-SEKSEIQLNVKELKRKLERAK------FLLPQVQTNTLQEEMWRQEEEL 281
Query: 585 PSSEKSPVMTPFKFWAWDPEEERRRQEK----------WQQEQERLLQERYQKEQDK-LK 633
EK K W +EER R+++ W+QE+ QE+ +EQ+K L+
Sbjct: 282 REQEKKIRKQEEKMWR---QEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELR 338
Query: 634 EEWEKAQKE--VEEEERRYYEEERKIIE 659
E+ E ++E ++E+E + +E+E K+ E
Sbjct: 339 EQKELREQEEQMQEQEEKMWEQEEKMRE 366
Score = 38.9 bits (89), Expect = 0.021
Identities = 32/127 (25%), Positives = 64/127 (50%), Gaps = 5/127 (3%)
Query: 604 EEER-RRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTV 662
EEER R +EK +E+E ++E+ +K Q + + WE+ +KE +++ R E++ K+ E
Sbjct: 448 EEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQ--RLPEQKEKLWEQEK 505
Query: 663 VPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRE 722
+ +Q E G K+ E++D+ W++ + D + + +E
Sbjct: 506 MQ-EQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQE 564
Query: 723 SDRLEEK 729
+R+E+K
Sbjct: 565 -ERMEKK 570
Score = 38.5 bits (88), Expect = 0.028
Identities = 31/167 (18%), Positives = 79/167 (47%), Gaps = 12/167 (7%)
Query: 130 LRKKKAEREEYRKSWSTATSPLGGERPFRSTSMFDMRCEEEAAVQPHSRARQEQLQLINN 189
LR+K+ E K W + E+ + EE+ + R R+++++
Sbjct: 406 LREKEERMREQEKMWEQVEK-MREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEE 464
Query: 190 QLREEDDK--------WQDDLARWKSRRRSVSQD-LIKKEEERKKMEKLLAGEDGTSERR 240
+RE+++K W+ + W+ +R ++ L ++E+ +++ EK+ E+ ++
Sbjct: 465 TMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQE 524
Query: 241 KSIKTYREIVQEKERRERE--LHEAYKNARSQEEAEGILQQYIERFT 285
+ +++ ++++ RE+E + E + R QE+ ++ +E+ T
Sbjct: 525 EMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKT 571
Score = 37.7 bits (86), Expect = 0.048
Identities = 25/135 (18%), Positives = 60/135 (44%), Gaps = 6/135 (4%)
Query: 131 RKKKAEREEYRKSWSTAT---SPLGGERPFRSTSMFDMRCEEEAAVQPHSRARQEQLQLI 187
+ +K +E+ +K+W ER + +M E+E +Q QEQ +
Sbjct: 691 KMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEE-- 748
Query: 188 NNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYR 247
+E+ W+ + W+ +R ++ + + E+ ++ EK+ E+ ++ + ++
Sbjct: 749 -EMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQE 807
Query: 248 EIVQEKERRERELHE 262
E ++ +E + R E
Sbjct: 808 EKMRGQEEKMRGQEE 822
Score = 36.6 bits (83), Expect = 0.11
Identities = 18/60 (30%), Positives = 36/60 (60%), Gaps = 3/60 (5%)
Query: 601 WDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEK---AQKEVEEEERRYYEEERKI 657
W EE+ QE+ QE ++E+ Q +++K++E+ EK ++++ E+E + +E KI
Sbjct: 832 WGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEKI 891
Score = 35.0 bits (79), Expect = 0.31
Identities = 29/133 (21%), Positives = 64/133 (48%), Gaps = 9/133 (6%)
Query: 602 DPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDT 661
+ EE+ + QE+ EQE ++E+ +K + + WE+ ++ E+E++ +EER +D
Sbjct: 345 EQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDE 404
Query: 662 VVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTR 721
+ +++ M E M + + + EK+ R ++ Q ++ ++ R
Sbjct: 405 RL-----REKEERMREQEKMWEQVEKMRE-EKKMQEQEKKTRDQEEKMQEEER---IRER 455
Query: 722 ESDRLEEKGSLTE 734
E EE+ ++ E
Sbjct: 456 EKKMREEEETMRE 468
Score = 34.7 bits (78), Expect = 0.40
Identities = 40/168 (23%), Positives = 80/168 (47%), Gaps = 24/168 (14%)
Query: 122 QTAYVPAPLRKKKAER--EEYRKSWSTATSPLGGERPFRSTSMFDMRCEEEAAVQ---PH 176
Q A R KKA+R EE K + L +R+T + ++ A +Q P
Sbjct: 182 QRALSAVSTRHKKADRYIEELTKERDALSLEL-----YRNTITNEELKKKNAELQEKLPL 236
Query: 177 SRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEE--------RKKMEK 228
+ + + ++QL +L+ + ++ + L + ++ ++ +++ ++EEE RK+ EK
Sbjct: 237 AESEKSEIQLNVKELKRKLERAKFLLPQVQTN--TLQEEMWRQEEELREQEKKIRKQEEK 294
Query: 229 LLAGEDGTSERRKSIKTYREIVQEKERR----ERELHEAYKNARSQEE 272
+ E+ E+ ++ E + +E+R E+EL E K R Q+E
Sbjct: 295 MWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKE 342
Score = 33.5 bits (75), Expect = 0.90
Identities = 26/131 (19%), Positives = 57/131 (43%), Gaps = 6/131 (4%)
Query: 138 EEYRKSWSTATSPLGGERPFRSTSMFDMR--CEEEAAVQPHS---RARQEQLQLINNQLR 192
E+ K W P E+ + M + E+E ++ R ++E+++ ++R
Sbjct: 759 EQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMR 818
Query: 193 EEDDK-WQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQ 251
+++K W + W + Q+ +E K EK+ E+ E+ + ++ E ++
Sbjct: 819 GQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMR 878
Query: 252 EKERRERELHE 262
E+E + R E
Sbjct: 879 EQEEKMRGQEE 889
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 58.5 bits (140), Expect = 3e-08
Identities = 137/612 (22%), Positives = 221/612 (36%), Gaps = 81/612 (13%)
Query: 217 IKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGI 276
+K EE+ K +EK E+ + + E+ +E+E+ +E + +EEAEG
Sbjct: 438 VKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGG 497
Query: 277 LQQY----IERFTISE-----AVLERLEMPKILERSHSTEPNLSSFLNDPNPMKYLRQQS 327
++ E E V E + P + E + + P K ++
Sbjct: 498 EEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEE 557
Query: 328 LPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKT 387
P + E A++ A SP K +P +P P+ ++ +K
Sbjct: 558 AKSPPEAKSPEKEEAKS-------PAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKE 610
Query: 388 FKVDGKVSVNGETVHREEEKE-RECPTVAPAHSLTKSQMFEGVARVHGSPLELKQDNGSI 446
+ K ++ +EE K E + A S TK + SP + K
Sbjct: 611 ---EAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEA--------KSPEKAKSP---- 655
Query: 447 EINIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQHFTTTVTRCSPT 506
+K + E A + K E S E K+ + E A S + + +
Sbjct: 656 ----EKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSP 711
Query: 507 VAFVEFPSSPQLKNDVSEEKDQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDK 566
V E S + K+ V EE K PE S E S + K KSPE TL K
Sbjct: 712 VK-EEAKSPEKAKSPVKEE--AKTPEKAKSPVKEEAKSPE--KAKSPEKAKTLDV----K 762
Query: 567 MPEANQLHLPNLNSQVDS-PSSEKSPV----------MTPFKFWAWDPEEE--RRRQEKW 613
PEA S D P KSPV +P K A PE+E ++ + K
Sbjct: 763 SPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKS 822
Query: 614 QQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSAD 673
++E QE KE K EE EKA + EE++ ++E ++ P
Sbjct: 823 PVKEEEKPQEVKVKEPPKKAEE-EKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPA 881
Query: 674 QLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESDRLEEKGSLT 733
S E ++E +D++ K ++ ++ +E + +EK T
Sbjct: 882 VEKPKESKVEAK-----------KEEAEDKK-KVPTPEKEAPAKVEVKEDAKPKEK---T 926
Query: 734 EGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQT------SNPTHSSE 787
E A + +K + + EA T + A+ P + +T + T S E
Sbjct: 927 EVAKKEPDDAKAKEPSKPAE-KKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKE 985
Query: 788 DVKPKTLPLDKS 799
KPK +KS
Sbjct: 986 PSKPKAEKAEKS 997
Score = 52.0 bits (123), Expect = 2e-06
Identities = 116/594 (19%), Positives = 218/594 (36%), Gaps = 78/594 (13%)
Query: 73 DGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRK 132
+ G + E+ P + + + A+ E KS ++ A V +P +
Sbjct: 493 EAEGGEEETKSPPAE--EAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKA 550
Query: 133 KKAEREEYRKSWSTATSPLGGERPFRSTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLR 192
K +EE KS A SP E + + + A + S A + + + ++
Sbjct: 551 KSPAKEE-AKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVK 609
Query: 193 EEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQE 252
EE A+ + +S ++ K E K EK + T E KS ++
Sbjct: 610 EE--------AKSPAEAKSPVKEEAKSPAEVKSPEK---AKSPTKEEAKS-------PEK 651
Query: 253 KERRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLEMPKILERSHSTEPNLSS 312
+ E+E ++ + A+S +AE + + +EA + E + S E S
Sbjct: 652 AKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSP 711
Query: 313 FLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTP---KAVPM 369
+++++ P K + V+ + + + SP K +P K + +
Sbjct: 712 ----------VKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDV 761
Query: 370 LTPKPYSQPKN-SQDVLKTFKVDGKVSVNGETVHREEEKER-ECPTVAPAHSLTKSQMFE 427
+P+ + K ++ F K V E E+ K + AP + K + +
Sbjct: 762 KSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVK 821
Query: 428 GVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSR--KGN 485
+ P E+K + P +E A T KTE K + K K
Sbjct: 822 SPVKEEEKPQEVKVK--------EPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPK 873
Query: 486 IELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKK---PENEMSGKVELV 542
+E EP VE P +++ E +D+KK PE E KVE+
Sbjct: 874 VE-EKKEPA---------------VEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEV- 916
Query: 543 LSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTPFKFWAWD 602
++ KPK A K P+ + P+ ++ + EK A
Sbjct: 917 --KEDAKPKEKTEVAK-------KEPDDAKAKEPSKPAEKKEAAPEKKDTKEEK---AKK 964
Query: 603 PEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERK 656
PEE+ + + K +++ + L +E + + +K ++ QK+ + E+ ++ K
Sbjct: 965 PEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATEDKAAK 1018
Score = 32.0 bits (71), Expect = 2.6
Identities = 22/82 (26%), Positives = 42/82 (51%), Gaps = 8/82 (9%)
Query: 575 LPNLNSQVDSPSSEKSPVMTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKE 634
+P++++ + S EK V+ + E+ + Q E+ ++ +E ++E+ + KE
Sbjct: 429 IPSVSTHIKVKSEEKIKVV--------EKSEKETVIVEEQTEETQVTEEVTEEEEKEAKE 480
Query: 635 EWEKAQKEVEEEERRYYEEERK 656
E K ++ EEEE EEE K
Sbjct: 481 EEGKEEEGGEEEEAEGGEEETK 502
>gi|4505101 microtubule-associated protein 7 [Homo sapiens]
Length = 749
Score = 56.2 bits (134), Expect = 1e-07
Identities = 147/710 (20%), Positives = 260/710 (36%), Gaps = 125/710 (17%)
Query: 173 VQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKK-EEERKKMEKLLA 231
V R +E+ + QL + W + R + ++ K+ EE+R+K E+ A
Sbjct: 63 VDDRQRLARERREEREKQLAAREIVWLEREERARQHYEKHLEERKKRLEEQRQKEERRRA 122
Query: 232 G-EDGTSERRKSIKTYREIV----QEKERRERELHEAYKNARSQEEAEGILQQYIERFTI 286
E+ +R + K E V E+ ++ ++ H + S + I +R ++
Sbjct: 123 AVEEKRRQRLEEDKERHEAVVRRTMERSQKPKQKHNRWSWGGSLHGSPSIHSADPDRRSV 182
Query: 287 SEAVLERLEMPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASV 346
S L + P I +R S+ L LN P+ + L+ L P + + S
Sbjct: 183 STMNLSKYVDPVISKRLSSSSATL---LNSPDRARRLQ---LSPWESSVVNRLLTPTHSF 236
Query: 347 LDTSMSAGSGSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHR--- 403
L S S + S P++ P + +NS D K F + S +H
Sbjct: 237 LARSKSTAALSGEAA---SCSPIIMPYKAAHSRNSMDRPKLFVTPPEGSSRRRIIHGTAS 293
Query: 404 -EEEKERE-------------CPTVAPAHSLTKSQMF---EGVARVHGSPLELKQ-DNGS 445
++E+ERE P+ A +S+++ + + + G+P GS
Sbjct: 294 YKKERERENVLFLTSGTRRAVSPSNPKARQPARSRLWLPSKSLPHLPGTPRPTSSLPPGS 353
Query: 446 IEI---NIKKPNS-----VPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQHFT 497
++ ++ P+ V +E+ EK +P + K S KG L E
Sbjct: 354 VKAAPAQVRPPSPGNIRPVKREVKVEPEKKDPEKEPQKVANEPSLKGRAPLVKVEE---- 409
Query: 498 TTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEMSGKVELVLSQKVVKPKSPEPEA 557
TV EE+ +PE + P S A
Sbjct: 410 ATV-----------------------EERTPAEPEVGPAAPAMAPAPASAPAPASAPAPA 446
Query: 558 TLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTPFKFWAWDPEE------ERRRQE 611
+ P + P +S V++ +S K+ T DPEE E+RR
Sbjct: 447 PVPTPAMVSAP----------SSTVNASASVKTSAGTT------DPEEATRLLAEKRRLA 490
Query: 612 KWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKI-IEDTVVPFTVSSS 670
+ Q+E+E + R Q+E ++ K E E AQ+ EE R EE R++ E
Sbjct: 491 REQREKEER-ERREQEELERQKRE-ELAQRVAEERTTRREEESRRLEAEQAREKEEQLQR 548
Query: 671 SADQLSTSSSMTEGSGTMNKIDLGNCQDE----KQDRRWKKSFQGDDSDLLLKTRESDRL 726
A++ + K + ++E +Q+R +K FQ ++ + L + + + +
Sbjct: 549 QAEERALREREEAERAQRQKEEEARVREEAERVRQER--EKHFQREEQERLERKKRLEEI 606
Query: 727 EEKGSLTEGALAHSGN----PVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSNP 782
++ TE + + ++KG TE A C TN P + +P
Sbjct: 607 MKRTRRTEATDKKTSDQRNGDIAKGALTG---GTEVSALPCTTNA-----PGNGKPVGSP 658
Query: 783 ----THSSEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSCGLPLG 828
+H S+ T L+K P+E S+ + LP+G
Sbjct: 659 HVVTSHQSKVTVESTPDLEK-------QPNENGVSVQNENFEEIINLPIG 701
Score = 45.1 bits (105), Expect = 3e-04
Identities = 78/333 (23%), Positives = 131/333 (39%), Gaps = 50/333 (15%)
Query: 87 KLPDVKKDDMSARRTSHGEPK--SAVPFNQYLPNKSNQTAYVPAPL-----RKKKAEREE 139
+ P VK ++ + + EP+ A P P + A PAP A
Sbjct: 401 RAPLVKVEEATVEERTPAEPEVGPAAPAMAPAPASAPAPASAPAPAPVPTPAMVSAPSST 460
Query: 140 YRKSWSTATSPLGGERPFRSTSMFDMR---CEEEAAVQPHSRARQEQLQLINNQLREEDD 196
S S TS G P +T + + E+ + R QE+L+ R++ +
Sbjct: 461 VNASASVKTSA-GTTDPEEATRLLAEKRRLAREQREKEERERREQEELE------RQKRE 513
Query: 197 KWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERR 256
+ +A ++ RR ++ E+ R+K E+L +R+ + RE +E ER
Sbjct: 514 ELAQRVAEERTTRREEESRRLEAEQAREKEEQL--------QRQAEERALRER-EEAERA 564
Query: 257 ERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLEMPKILERSHSTEPNLSSFLND 316
+R+ E AR +EEAE + Q+ + F E ERLE K LE
Sbjct: 565 QRQKEE---EARVREEAERVRQEREKHFQREEQ--ERLERKKRLEEI------------- 606
Query: 317 PNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTP-KAVPMLTPKPY 375
MK R+ K + IA+ ++ T + S P T P P+ +P
Sbjct: 607 ---MKRTRRTEATDKKTSDQRNGDIAKGAL--TGGTEVSALPCTTNAPGNGKPVGSPHVV 661
Query: 376 SQPKNSQDVLKTFKVDGKVSVNGETVHREEEKE 408
+ ++ V T ++ + + NG +V E +E
Sbjct: 662 TSHQSKVTVESTPDLEKQPNENGVSVQNENFEE 694
>gi|238908501 sciellin isoform 3 [Homo sapiens]
Length = 646
Score = 54.7 bits (130), Expect = 4e-07
Identities = 43/177 (24%), Positives = 75/177 (42%), Gaps = 24/177 (13%)
Query: 710 QGDDSDLLLKT-----RESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCG 764
Q D D L+K R ++R + +L E V+ V E+ + GA G
Sbjct: 481 QSQDLDNLIKVKPSALRNTNRDQNLENLIE---------VNSHVSENKNGSSNTGAKQAG 531
Query: 765 TNPQLAQDPSQNQQTSNPTHS-SEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSC 823
+ + + + +P E++ K + + S S+R S+ + +C+ C
Sbjct: 532 PQDTVVYTRTYVENSKSPKDGYQENISGKYI-------QTVYSTSDR--SVIERDMCTYC 582
Query: 824 GLPLGKGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMR 880
PLG MI++ L + H CF+C ICK L + +G + I ++C CY +
Sbjct: 583 RKPLGVETKMILDELQICCHSTCFKCEICKQPLENLQAGDSIWIYRQTIHCEPCYSK 639
>gi|238908499 sciellin isoform 1 [Homo sapiens]
Length = 688
Score = 54.7 bits (130), Expect = 4e-07
Identities = 43/177 (24%), Positives = 75/177 (42%), Gaps = 24/177 (13%)
Query: 710 QGDDSDLLLKT-----RESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCG 764
Q D D L+K R ++R + +L E V+ V E+ + GA G
Sbjct: 523 QSQDLDNLIKVKPSALRNTNRDQNLENLIE---------VNSHVSENKNGSSNTGAKQAG 573
Query: 765 TNPQLAQDPSQNQQTSNPTHS-SEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSC 823
+ + + + +P E++ K + + S S+R S+ + +C+ C
Sbjct: 574 PQDTVVYTRTYVENSKSPKDGYQENISGKYI-------QTVYSTSDR--SVIERDMCTYC 624
Query: 824 GLPLGKGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMR 880
PLG MI++ L + H CF+C ICK L + +G + I ++C CY +
Sbjct: 625 RKPLGVETKMILDELQICCHSTCFKCEICKQPLENLQAGDSIWIYRQTIHCEPCYSK 681
>gi|238908497 sciellin isoform 2 [Homo sapiens]
Length = 668
Score = 54.7 bits (130), Expect = 4e-07
Identities = 43/177 (24%), Positives = 75/177 (42%), Gaps = 24/177 (13%)
Query: 710 QGDDSDLLLKT-----RESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCG 764
Q D D L+K R ++R + +L E V+ V E+ + GA G
Sbjct: 503 QSQDLDNLIKVKPSALRNTNRDQNLENLIE---------VNSHVSENKNGSSNTGAKQAG 553
Query: 765 TNPQLAQDPSQNQQTSNPTHS-SEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSC 823
+ + + + +P E++ K + + S S+R S+ + +C+ C
Sbjct: 554 PQDTVVYTRTYVENSKSPKDGYQENISGKYI-------QTVYSTSDR--SVIERDMCTYC 604
Query: 824 GLPLGKGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMR 880
PLG MI++ L + H CF+C ICK L + +G + I ++C CY +
Sbjct: 605 RKPLGVETKMILDELQICCHSTCFKCEICKQPLENLQAGDSIWIYRQTIHCEPCYSK 661
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 53.9 bits (128), Expect = 6e-07
Identities = 134/645 (20%), Positives = 253/645 (39%), Gaps = 113/645 (17%)
Query: 136 EREEYRKS-WSTATSPLGGERPFRSTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREE 194
ER++Y K+ STA + + S S +M EE + R +L Q +E
Sbjct: 257 ERKDYLKTDISTALKEIRSQ--LESHSDQNMHQAEE-----WFKCRYAKLTEAAEQNKEA 309
Query: 195 DDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKE 254
++++A ++ + +S S +L ++ +E+ L+ D + +Y++ +Q+ E
Sbjct: 310 IRSAKEEIAEYRRQLQSKSIELESVRGTKESLERQLS--DIEERHNHDLSSYQDTIQQLE 367
Query: 255 RRERELHEAYKNARSQEEAEGILQQYIERFTISEAV-LERLEMPKILERSHSTEPNLSSF 313
R ++ E L++Y + + A+ +E K+LE E S+F
Sbjct: 368 NELRG---------TKWEMARHLREYQDLLNVKMALDIEIAAYRKLLE---GEETRFSTF 415
Query: 314 LNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPK 373
Y + PP T+ + I + V +P V K V + +
Sbjct: 416 AGSITGPLYTHR----PP---ITISSKIQKPKV---------EAPKLKVQHKFVEEIIEE 459
Query: 374 PYSQPKNSQ--DVLKTFKVDGKVSVNGETVHREEEKERECPTVAPAHSLTKSQMFEGVAR 431
+ + S+ + L + VS+ E EEKE E + KS
Sbjct: 460 TKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSP------- 512
Query: 432 VHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASS 491
V + E+K++ G E + ++ A +++ E +GG ++G+ E
Sbjct: 513 VKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAE--------EGGSEKEGSSEKEEG 564
Query: 492 EPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPEN---EMSGKVELVLSQKVV 548
E + E + + + + +E K++KK E E++ K ELV KV
Sbjct: 565 EQE----------------EGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVE 608
Query: 549 KP---KSPEPEATLTFPF---LDKMPEANQLHLPNLNSQVD---------SPSSE--KSP 591
KP KSP P++ + + K P + P S V+ SP E KSP
Sbjct: 609 KPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSP 668
Query: 592 V-MTPFKFWAWDP------EEERRRQE--KWQQEQERLLQERYQKEQDKLKEEWEKAQKE 642
V +P + A P EE + + E K +Q++E + + +++K++++ EK +
Sbjct: 669 VSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDV 728
Query: 643 VEEEERRYYEEERKIIEDTVVPFTV-------SSSSADQLSTSSSMTEGSGTMNKIDLGN 695
E+++ +E + E + +V + L + G + G+
Sbjct: 729 PEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGS 788
Query: 696 CQDEKQDRRWKKSFQG-----DDSDLLLKTRESDRLEEKGSLTEG 735
+ K R+ + G ++ + K + S R EEKG +T G
Sbjct: 789 DKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVVTNG 833
Score = 35.4 bits (80), Expect = 0.24
Identities = 70/367 (19%), Positives = 137/367 (37%), Gaps = 66/367 (17%)
Query: 132 KKKAEREEYRKSWSTATSPLGGERPFRSTSMFDMRCEEEAAVQPHSRARQEQLQLINNQL 191
KK+A E+ + + + P ++T+ +EE + ++E+
Sbjct: 488 KKEAAEEKEEEPEAEEEEVAAKKSPVKATAP---EVKEEEGEKEEEEGQEEE-------- 536
Query: 192 REEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQ 251
EED+ + D A + S + + E+E + E GE+ ++ K ++ E V
Sbjct: 537 EEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVA 596
Query: 252 EKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLEMPKILERSHSTEPNLS 311
KE EL K + ++ + + +E E+ S P
Sbjct: 597 TKE----ELVADAKVEKPEKAKSPVPKSPVE------------------EKGKSPVPK-- 632
Query: 312 SFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLT 371
+P++ + +P ++ + ++ V + S S SP V KA +
Sbjct: 633 ------SPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSP---VEEKAKSPVP 683
Query: 372 PKPYSQPKNSQDVLK-----TFKVDGKVSVNGETVHREEEKERECPTVAPAHSLTKSQMF 426
P + K+ +V K + + K + E V ++EEK ++ P A S K +
Sbjct: 684 KSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAV 743
Query: 427 EGVARVHGSPLELKQDNGSIEINIKKPNS-----VPQELAATTEKTEPNSQEDKNDGGK- 480
V + S++++++K + QE E S+E+ +D G
Sbjct: 744 AEVVTI----------TKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAK 793
Query: 481 -SRKGNI 486
SRK +I
Sbjct: 794 GSRKEDI 800
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 53.5 bits (127), Expect = 8e-07
Identities = 83/427 (19%), Positives = 170/427 (39%), Gaps = 62/427 (14%)
Query: 404 EEEKERECPTVAPAH-SLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAA 462
E +KE + PT+ A SL +M A + E K ++ I++ +V +
Sbjct: 116 ERQKEFD-PTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQK 174
Query: 463 TTEK-TEPNSQEDKN----DGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQ 517
+ E N +EDK + K ++G+I E T TV
Sbjct: 175 NDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVM-------S 227
Query: 518 LKNDVSEEKDQKKPENEMSGKVELVLSQKVV---KPKSPEPEATLTFPFLDKMPEANQLH 574
LKN ++ K+ E G E+ +K+ K ++ A L +++
Sbjct: 228 LKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKK 287
Query: 575 LPNLNSQVDSPSSEKSPVMTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKE 634
+ + +++++ EK+ +ER R+E ++E+ R ++R +E+ ++KE
Sbjct: 288 IADERARIEA--EEKAAA------------QERERREAEERERMREEEKRAAEERQRIKE 333
Query: 635 EWEKAQKE---VEEEERRYYEEERKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKI 691
E ++A +E ++EEE+R EE ++I E+ +A++ + + E + +
Sbjct: 334 EEKRAAEERQRIKEEEKRAAEERQRIKEE-------EKRAAEERQRARAEEEEKAKVEEQ 386
Query: 692 DLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHED 751
+EK+ + +G+ ++E+K G V++ ++
Sbjct: 387 KRNKQLEEKKHAMQETKIKGE------------KVEQK---------IEGKWVNEKKAQE 425
Query: 752 HQLDTEAGAPHCGTNPQLAQDPSQNQQTSNPTHSSEDVKPKTLPLDKSINHQIESPSERR 811
+L T Q + Q PT E++K + + DK +++S +R+
Sbjct: 426 DKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRK 485
Query: 812 KSISGKK 818
K + K
Sbjct: 486 KGFTEVK 492
Score = 51.2 bits (121), Expect = 4e-06
Identities = 66/280 (23%), Positives = 116/280 (41%), Gaps = 45/280 (16%)
Query: 404 EEEKERECPTVAPAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAAT 463
EEE RE A L + Q E + +V +E+N + NSVP E A T
Sbjct: 34 EEEAARERRRRARQERLRQKQEEESLGQV----------TDQVEVNAQ--NSVPDEEAKT 81
Query: 464 TEKTEPNSQEDKNDGG----------KSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFP 513
T N+Q + +D + R+ ++ A + F T+T S ++
Sbjct: 82 TTT---NTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLP----- 133
Query: 514 SSPQLKNDVSEEKDQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFL---DKMPEA 570
S +++ND +E + +K E S + + + KS + DK E
Sbjct: 134 -SRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEE 192
Query: 571 NQLHLPNLNS----QVD------SPSSEKSPVMTPFKFWAWDPEEERRRQEKWQQEQERL 620
+ P S QV+ + S++ V+ K EE ++ +E+ +Q + +
Sbjct: 193 EEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEER-EQGSDEI 251
Query: 621 LQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIED 660
+E+DK + E E+A+ E EE ER E+++KI ++
Sbjct: 252 SHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADE 291
Score = 47.8 bits (112), Expect = 5e-05
Identities = 143/739 (19%), Positives = 272/739 (36%), Gaps = 119/739 (16%)
Query: 77 SDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAE 136
+D+ LP R++ ++D + T+ E KS +S Q Y + + +
Sbjct: 126 TDASLSLPSRRM----QNDTAENETTEKEEKS----------ESRQERY---EIEETETV 168
Query: 137 REEYRKS-WSTATSPLGGERPFRSTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREED 195
+ Y+K+ W A D EEE +P + E + + E+
Sbjct: 169 TKSYQKNDWRDA----------EENKKEDKEKEEEEEEKPKRGSIGENQ--VEVMVEEKT 216
Query: 196 DKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKER 255
+ Q++ + +S + K+EEER++ ++ + E K E E
Sbjct: 217 TESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEE 276
Query: 256 RERELHE-----AYKNARSQEEAEGILQQYIERFTISEAVLERLEMPKILERSHSTEPNL 310
RER E A + AR + E + Q+ R + E ER E
Sbjct: 277 RERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEK 336
Query: 311 SSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPKAVPML 370
+ + ++++ + ++ RA+ A +K K L
Sbjct: 337 RA----AEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQL 392
Query: 371 TPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVAPAHSLTKSQMFEGVA 430
K ++ + +K KV+ K + G+ V+ ++ +E + T ++ K Q E
Sbjct: 393 EEKKHAMQETK---IKGEKVEQK--IEGKWVNEKKAQEDKLQT-----AVLKKQGEEKGT 442
Query: 431 RVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELAS 490
+V +L++D KP +E+ K + +E+ +KG E+ S
Sbjct: 443 KVQAKREKLQED---------KPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKS 493
Query: 491 SEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEMSGKVELVL------- 543
+ T + T S P + V ++ + P+ E ++E +
Sbjct: 494 QNGEFMTHKLKHTENTF------SRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETE 547
Query: 544 SQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTPFKFWAWDP 603
S++ K K + EA L L K E E+ V+ +
Sbjct: 548 SEEFEKLKQKQQEAALELEELKKKRE------------------ERRKVL--------EE 581
Query: 604 EEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVV 663
EE+RR+QE E +R L+E ++E+ +LKEE E+ + E E+ ++ E+ +
Sbjct: 582 EEQRRKQE----EADRKLRE--EEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFK 635
Query: 664 PFTVSSSS------ADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLL 717
FT SS A+ L+ S + G + ++ + + D + + ++ + +G S
Sbjct: 636 CFTPKGSSLKIEERAEFLNKSVQKSSGVKSTHQAAIVSKIDSRLE-QYTSAIEGTKSAKP 694
Query: 718 LKTRESD-RLEEKGSLTEGALAHSGN----PVSKGVHEDHQLDTEAGAPHCGTNPQLAQD 772
K SD + +G ++ GN P + G + G N L +
Sbjct: 695 TKPAASDLPVPAEGVRNIKSMWEKGNVFSSPTAAGTPNKETAGLKVGV-SSRINEWLTKT 753
Query: 773 PSQNQQTSNPTHSSEDVKP 791
P N+ +P D++P
Sbjct: 754 PDGNK---SPAPKPSDLRP 769
Score = 35.0 bits (79), Expect = 0.31
Identities = 43/206 (20%), Positives = 86/206 (41%), Gaps = 23/206 (11%)
Query: 602 DPEEERRRQEKWQQEQERLLQER--YQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIE 659
D E RR + ++E+ RL ER YQ+ D +E + ++ +E R +EE + +
Sbjct: 2 DDFERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQ 61
Query: 660 DT-VVPFTVSSSSADQ---LSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGD--- 712
T V +S D+ +T+++ EG ++ ++E++ +R +++ +
Sbjct: 62 VTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEF 121
Query: 713 -----DSDLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQL-DTEAGAPHCGTN 766
D+ L L +R + TE S+ E +++ +TE N
Sbjct: 122 DPTITDASLSLPSRRMQNDTAENETTE------KEEKSESRQERYEIEETETVTKSYQKN 175
Query: 767 PQLAQDPSQNQQTSNPTHSSEDVKPK 792
+D +N++ E+ KPK
Sbjct: 176 DW--RDAEENKKEDKEKEEEEEEKPK 199
>gi|22758136 MAP7 domain containing 2 [Homo sapiens]
Length = 732
Score = 52.8 bits (125), Expect = 1e-06
Identities = 101/480 (21%), Positives = 181/480 (37%), Gaps = 74/480 (15%)
Query: 219 KEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERR-----ERELHEAYKNARSQEEA 273
K +ER+++ K + ER K + + + EK++R E+++ E ++ Q +
Sbjct: 50 KSDERQRLAK-----ERREEREKCLAAREQQILEKQKRARLQYEKQMEERWRKLEEQRQR 104
Query: 274 EGILQQYIE--RFTISEAVLERLE--MPKILERSHSTEPNLSSFLNDP---NPMKYLRQQ 326
E + +E R ERLE M + LER+ E P P +
Sbjct: 105 EDQKRAAVEEKRKQKLREEEERLEAMMRRSLERTQQLELKKKYSWGAPLAIGPGGHDACD 164
Query: 327 SLPPPKFTATVETTIARASVLDTSMSAGSGSPSKT--VTPKAVPM--LTPKPYSQPKNSQ 382
L + T L +S A S SP + V P+ P+ L P S P +
Sbjct: 165 KLSTSTMSLPKPTEPPMNKRLSSSTVAISYSPDRVFHVCPRLAPLGPLNPSYKSSPTRNI 224
Query: 383 DVLKTFKVD-------GKVSVNG------ETVHREEEKERECPTVAPAHSLTKSQMFEGV 429
+ K GK +++G E V R + P V L + + G+
Sbjct: 225 EKKKATSTSTSGAGDVGKEALSGGEASLVEKVKRGQRTATSLPVVNFGSPLRRCEFSGGI 284
Query: 430 ARVHGSPLELKQDNGSIEINIK--KP----NSVPQELAATTEKTEPNSQEDKNDGGKSRK 483
+ SP+ K + + K KP + V L A + + P + +K K R+
Sbjct: 285 PKRPSSPVISKTATKAYPQSPKTTKPPYPGSPVKYRLPALSGQDMPKRKAEKEKSNKERE 344
Query: 484 GNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEMSGKVELVL 543
G + ++ PQ L+ V ++ +K GK E
Sbjct: 345 GTLAQQAAGPQ-------------------GEEALEKHVVDKHASEKHAAAAGGKAEN-- 383
Query: 544 SQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTPFKFWAWDP 603
S + KP + +A L + + Q L + + E+ D
Sbjct: 384 SAALGKPTAGTTDAGEAAKILAE--KRRQARLQKEQEEQERVEKEEQ-----------DR 430
Query: 604 EEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVV 663
E + K ++E+ RL +E ++E+++ ++E EK ++E EE+ + E +RK E+ ++
Sbjct: 431 LEREELKRKAEEERLRLEEEARKQEEERKRQEEEKKKQEGEEKRKAGEEAKRKAEEELLL 490
Score = 45.8 bits (107), Expect = 2e-04
Identities = 40/171 (23%), Positives = 80/171 (46%), Gaps = 21/171 (12%)
Query: 170 EAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRS------VSQDLIKKEEER 223
EAA + RQ +LQ + + + QD L R + +R++ + ++ K+EEER
Sbjct: 399 EAAKILAEKRRQARLQKEQEEQERVEKEEQDRLEREELKRKAEEERLRLEEEARKQEEER 458
Query: 224 KKMEKLLAGEDGTSERRKSIKTYREIVQE---KERRERELHEAYKNARSQEEAEGILQQY 280
K+ E+ ++G +R+ + R+ +E KE++E+E E + +E AE ++
Sbjct: 459 KRQEEEKKKQEGEEKRKAGEEAKRKAEEELLLKEKQEQEKQEKAMIEKQKEAAETKAREV 518
Query: 281 IERFTIS-EAVLERLEMPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPP 330
E+ + E ++ ++E ++ + E MK R+ +PP
Sbjct: 519 AEQMRLEREQIMLQIEQERLERKKRIDE-----------IMKRTRKSDVPP 558
Score = 42.7 bits (99), Expect = 0.001
Identities = 43/155 (27%), Positives = 71/155 (45%), Gaps = 21/155 (13%)
Query: 128 APLRKKKAEREEYRKSWSTATSPLGGERPFRSTSMFDMRCEEEAAVQPHSRARQEQLQLI 187
A L+K++ E+E K L E R +R EEEA Q R RQE+ +
Sbjct: 411 ARLQKEQEEQERVEKE---EQDRLEREELKRKAEEERLRLEEEARKQEEERKRQEEEK-- 465
Query: 188 NNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLL------AGEDGTSERRK 241
Q EE K A +++R++ + L+K+++E++K EK + A E E +
Sbjct: 466 KKQEGEEKRK-----AGEEAKRKAEEELLLKEKQEQEKQEKAMIEKQKEAAETKAREVAE 520
Query: 242 SIKTYRE-----IVQEKERRERELHEAYKNARSQE 271
++ RE I QE+ R++ + E K R +
Sbjct: 521 QMRLEREQIMLQIEQERLERKKRIDEIMKRTRKSD 555
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 51.6 bits (122), Expect = 3e-06
Identities = 98/511 (19%), Positives = 196/511 (38%), Gaps = 70/511 (13%)
Query: 166 RCEEEAAVQPHS-RARQEQLQLINNQLREEDDKWQDD---LARWKSRRRSVSQDLIKKEE 221
R EEE Q R ++E++ +LRE++ K ++ + R + R R ++L ++E+
Sbjct: 238 RQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEK 297
Query: 222 ERKKMEKLLAGEDGTSERRKSIKTYREIVQEKE----RRERELHEAYKNARSQEEAEGIL 277
E ++ +KL E+ E+ + + E ++E+E R+E L E K R QE + +
Sbjct: 298 ELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQE--QKMR 355
Query: 278 QQYIERFTISEAVLERLEMPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATV 337
Q + E + E+ E + E+ E + K +R++
Sbjct: 356 DQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEE---------- 405
Query: 338 ETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVN 397
ET + + K + +P K + Q K + K ++ + K+
Sbjct: 406 ETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQ 465
Query: 398 GETVHRE-----EEKERECPTVAPAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKK 452
E +E +EK RE + QM+E ++ ++ +
Sbjct: 466 EEMWGQEKKMWRQEKMRE----------QEDQMWEQEEKMRDQEQKMWDQEERM------ 509
Query: 453 PNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEF 512
E + E +E K + K E + E + T +
Sbjct: 510 -----WEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTW------------DQ 552
Query: 513 PSSPQLKNDVSEEKDQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQ 572
+ + + E + + + E EM + E + ++ K + E + + +KM E +
Sbjct: 553 EEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKM---WEQEEKMQEQEE 609
Query: 573 LHLPNLNSQVDSPSSEKSPVMTPFKFWAWDPEEERRRQEK--WQQEQERLLQERYQKEQD 630
+ +K M + W+ EE+ + QE+ W+QE++ QE +EQ+
Sbjct: 610 KMWEQEEKMWEQEEEDK---MQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQE 666
Query: 631 KLKEEWEKAQKEVEE----EERRYYEEERKI 657
+ + E+ +E EE +E + E+E K+
Sbjct: 667 EKMQGQEEKMREQEEKMQGQEEKMREQEEKM 697
Score = 51.6 bits (122), Expect = 3e-06
Identities = 98/510 (19%), Positives = 201/510 (39%), Gaps = 75/510 (14%)
Query: 165 MRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERK 224
+R +EE + R R+++ ++RE+++K + R + R R ++L ++E+E +
Sbjct: 250 IRKQEEKMWRQEERLREQE-----GKMREQEEK----MRRQEKRLREQEKELREQEKELR 300
Query: 225 KMEKLLAGEDGTSERRKSIKTYREIVQEKE----RRERELHEAYKNARSQEEAEGILQQY 280
+ +KL E+ E+ + + E ++E+E R+E L E K R QE+ + Q
Sbjct: 301 EQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQK--MRDQE 358
Query: 281 IERFTISEAVLERLEMPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETT 340
+ E + E+ E + E+ E + K +R++ ET
Sbjct: 359 ERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEE----------ETM 408
Query: 341 IARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGET 400
+ + K + +P K + Q K + K ++ + K+ E
Sbjct: 409 REQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEM 468
Query: 401 VHRE-----EEKERECPTVAPAHSLTKSQMFEGVARVHGSPLELKQDNGSI---EINIKK 452
+E +EK RE + QM+E ++ ++ + + +++
Sbjct: 469 WGQEKKMWRQEKMRE----------QEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLRE 518
Query: 453 PNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFV-E 511
+E ++ E +E K + + + E E + + + E
Sbjct: 519 KEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMRE 578
Query: 512 FPSSPQLKNDVSEEKDQK--KPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPE 569
Q + + E+++K + E +M + E + Q+ + E DKM E
Sbjct: 579 QEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEE---------DKMQE 629
Query: 570 ANQLHLPNLNSQVDSPSSEKSPVMTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQ 629
++ E+ M + W+ EE+ R QE+ +EQE E+ Q ++
Sbjct: 630 QEEM------------MWEQEEKMQEQEEKMWEQEEKMREQEEKMREQE----EKMQGQE 673
Query: 630 DKLKEEWEKAQ----KEVEEEERRYYEEER 655
+K++E+ EK Q K E+EE+ +EE+
Sbjct: 674 EKMREQEEKMQGQEEKMREQEEKMRGQEEK 703
Score = 47.4 bits (111), Expect = 6e-05
Identities = 35/141 (24%), Positives = 68/141 (48%), Gaps = 18/141 (12%)
Query: 601 WDPEEERRRQEK--WQQE-----QERLLQERYQKEQDKLKEEWEKAQKEVEEEER----- 648
W+ EE+ R QE+ W+QE QE+ ++E+ QK +D+ + WE+ ++ E+EER
Sbjct: 320 WEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQE 379
Query: 649 RYYEEERKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKS 708
+ +E+E K+ E+ + +M E M K + E++++ W++
Sbjct: 380 KMWEQEEKMQEEE----RIREREKKMREEEETMREQEEKMQKQE--ENMWEQEEKEWQQQ 433
Query: 709 FQGDDSDLLLKTRESDRLEEK 729
+ + L + + EEK
Sbjct: 434 RLPEQKEKLWEQEKMQEQEEK 454
Score = 42.0 bits (97), Expect = 0.003
Identities = 44/186 (23%), Positives = 83/186 (44%), Gaps = 28/186 (15%)
Query: 138 EEYRKSWSTATSPLGGERPFRSTSMFD-----------MRCEEEAAVQPHSRARQEQLQL 186
E+ K W P E+ + M + +R +EE Q RQE+++
Sbjct: 424 EQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMRE 483
Query: 187 INNQLREEDDKWQDDLAR-WKSRRRSVSQD--LIKKEEERKKMEKLLAGEDGTSERRKSI 243
+Q+ E+++K +D + W R QD L +KEE ++ +K+ E+ E +K+
Sbjct: 484 QEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQ 543
Query: 244 ----KTY--------REIVQEKERRERELHEAYK--NARSQEEAEGILQQYIERFTISEA 289
KT+ E ++E+E++ RE E + + QE+ E + +Q + + E
Sbjct: 544 EQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEK 603
Query: 290 VLERLE 295
+ E+ E
Sbjct: 604 MQEQEE 609
Score = 42.0 bits (97), Expect = 0.003
Identities = 31/132 (23%), Positives = 64/132 (48%), Gaps = 14/132 (10%)
Query: 601 WDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKA---QKEVEEEERRYYEEERKI 657
W+ +E R +E+ +EQ+++ Q+ + ++K +E EK Q+E EE R E E+K+
Sbjct: 510 WEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKM 569
Query: 658 IEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLL 717
E+ + +Q M E M + Q+EK + +K ++ ++ +
Sbjct: 570 REEEEMMREQEEKMQEQ---EEKMREQEEKMWE------QEEKMQEQEEKMWEQEEK--M 618
Query: 718 LKTRESDRLEEK 729
+ E D+++E+
Sbjct: 619 WEQEEEDKMQEQ 630
Score = 41.2 bits (95), Expect = 0.004
Identities = 38/140 (27%), Positives = 61/140 (43%), Gaps = 13/140 (9%)
Query: 533 NEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQV--------DS 584
NE K L +K+ +S + E L L + E + LP + + +
Sbjct: 182 NEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEE 241
Query: 585 PSSEKSPVMTPFKFWAWDPEEERRRQEKWQQEQERLL--QERYQKEQDKLKEEWEK---A 639
E+ + + W EE R QE +EQE + QE+ +EQ+K E EK
Sbjct: 242 ELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELRE 301
Query: 640 QKEVEEEERRYYEEERKIIE 659
QK++ E+E + E+E K+ E
Sbjct: 302 QKKLREQEEQMQEQEEKMWE 321
Score = 39.7 bits (91), Expect = 0.013
Identities = 24/71 (33%), Positives = 44/71 (61%), Gaps = 11/71 (15%)
Query: 601 WDPEEERRRQEK--WQQEQ------ERLLQ-ERYQKEQDKL--KEEWEKAQKEVEEEERR 649
W+ EE+ R QE+ W QE+ ERL + E +EQ K+ +EE + +K+ +E+E++
Sbjct: 489 WEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKK 548
Query: 650 YYEEERKIIED 660
+++E K+ E+
Sbjct: 549 TWDQEEKMREE 559
Score = 38.9 bits (89), Expect = 0.021
Identities = 34/129 (26%), Positives = 61/129 (47%), Gaps = 11/129 (8%)
Query: 602 DPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRY-YEEERKIIED 660
+ EE R QE+ QEQE ++E+ +K ++ ++ E+ +K E+EE+ + EEE K+ E
Sbjct: 571 EEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQ 630
Query: 661 TVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKT 720
+ + +Q M E M + Q+EK R ++ QG + + +
Sbjct: 631 EEMMWEQEEKMQEQ---EEKMWEQEEKMRE------QEEKM-REQEEKMQGQEEKMREQE 680
Query: 721 RESDRLEEK 729
+ EEK
Sbjct: 681 EKMQGQEEK 689
Score = 37.7 bits (86), Expect = 0.048
Identities = 36/142 (25%), Positives = 65/142 (45%), Gaps = 19/142 (13%)
Query: 524 EEKDQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVD 583
EEK QK+ EN + + Q++ + K E +K+ E + + Q +
Sbjct: 412 EEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEE----KIRDQEE 467
Query: 584 SPSSEKSPVMTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEV 643
EK K W +E+ R QE EQE ++++ QK D+ + WE+ ++
Sbjct: 468 MWGQEK-------KMWR---QEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLR 517
Query: 644 EEEER-----RYYEEERKIIED 660
E+EER + +++E K+ E+
Sbjct: 518 EKEERMREQKKMWQQEEKMREE 539
Score = 37.4 bits (85), Expect = 0.062
Identities = 35/153 (22%), Positives = 68/153 (44%), Gaps = 9/153 (5%)
Query: 130 LRKKKAEREEYRKSWSTATSPLGGERPFRSTSMFDMRCEEEAAVQPHSRARQEQLQLINN 189
LR++K RE+ + E R R EE Q QEQ
Sbjct: 299 LREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQ------ 352
Query: 190 QLREEDDK-W-QDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYR 247
++R+++++ W QD+ R K R + + ++EE+ ++ E++ E E ++++
Sbjct: 353 KMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQE 412
Query: 248 EIVQEKERRERELHE-AYKNARSQEEAEGILQQ 279
E +Q++E E E ++ R E+ E + +Q
Sbjct: 413 EKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQ 445
Score = 37.0 bits (84), Expect = 0.082
Identities = 34/143 (23%), Positives = 61/143 (42%), Gaps = 26/143 (18%)
Query: 604 EEER-RRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEE-----------EERRYY 651
EEER R +EK +E+E ++E+ +K Q + + WE+ +KE ++ E+ +
Sbjct: 390 EEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQ 449
Query: 652 EEERKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQG 711
E+E KI E Q E G K+ E++D+ W++ +
Sbjct: 450 EQEEKIWE--------------QEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKM 495
Query: 712 DDSDLLLKTRESDRLEEKGSLTE 734
D + + +E E+ L E
Sbjct: 496 RDQEQKMWDQEERMWEQDERLRE 518
Score = 37.0 bits (84), Expect = 0.082
Identities = 57/275 (20%), Positives = 108/275 (39%), Gaps = 51/275 (18%)
Query: 130 LRKKKAEREEYRKSWSTATSPLGGERPFRSTSMF----DMRCEEEAAVQPHSRARQEQLQ 185
+R++K +E+ +K+W ER +M E+E +Q +EQ +
Sbjct: 536 MREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEE 595
Query: 186 LINNQ---LREEDDK-WQDDLARWKSRRRSVSQDL------------------------I 217
+ Q ++E+++K W+ + W+ Q+ +
Sbjct: 596 KMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKM 655
Query: 218 KKEEE--RKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEG 275
+++EE R++ EK+ E+ E+ + ++ QE++ RE+E + R QEE
Sbjct: 656 REQEEKMREQEEKMQGQEEKMREQEEKMQG-----QEEKMREQE-----EKMRGQEEK-- 703
Query: 276 ILQQYIERFTISEAVLERLEMPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTA 335
+ Q + + E + + EM + ER + + L P + + LPP K
Sbjct: 704 MWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERL--PEHEERCSEPCLPPSKVLC 761
Query: 336 TVETTIARASVLDTSMSAGSGSPSKTVTPKAVPML 370
+ T SV AG GSP T + + L
Sbjct: 762 NMSHT---GSVEPAGGEAGEGSPQDNPTAQEIMQL 793
Score = 36.6 bits (83), Expect = 0.11
Identities = 32/146 (21%), Positives = 70/146 (47%), Gaps = 16/146 (10%)
Query: 130 LRKKKAEREEYRKSWSTATSPLGGERPFRSTSMFDMRCEEEAAVQPHSRARQEQLQLINN 189
LR+K+ E K W ER MR EEE R ++E++Q
Sbjct: 368 LREKEERMREQEKMWEQEEKMQEEERIREREKK--MREEEETM-----REQEEKMQ---- 416
Query: 190 QLREEDDKWQDDLARWKSRRRSVSQD-LIKKEEERKKMEKLLAGEDGTSERRKSIKTYRE 248
++E++ W+ + W+ +R ++ L ++E+ +++ EK+ E+ ++ + ++
Sbjct: 417 --KQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKK 474
Query: 249 IVQEKERRERE--LHEAYKNARSQEE 272
+ ++++ RE+E + E + R QE+
Sbjct: 475 MWRQEKMREQEDQMWEQEEKMRDQEQ 500
Score = 35.8 bits (81), Expect = 0.18
Identities = 31/146 (21%), Positives = 64/146 (43%), Gaps = 10/146 (6%)
Query: 524 EEKDQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVD 583
EE+D+ + + EM + E + ++ K E + + + E Q + Q +
Sbjct: 622 EEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEE 681
Query: 584 SPSSEKSPVMTPFKFWAWDPEEERRRQEK--WQQEQERLLQERYQKEQDKLKEEWEKAQK 641
++ + + EE+ R QE+ W QE++ QE Q++++E+ E+ +
Sbjct: 682 KMQGQEEKMR--------EQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRD 733
Query: 642 EVEEEERRYYEEERKIIEDTVVPFTV 667
+ E+ + R E E + E + P V
Sbjct: 734 QKEKMQERLPEHEERCSEPCLPPSKV 759
Score = 34.3 bits (77), Expect = 0.53
Identities = 17/59 (28%), Positives = 35/59 (59%)
Query: 602 DPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIED 660
+ EE+ + QE+ EQE ++E+ +K + + WE+ ++ E+E++ +EER +D
Sbjct: 307 EQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQD 365
Score = 31.6 bits (70), Expect = 3.4
Identities = 43/183 (23%), Positives = 84/183 (45%), Gaps = 27/183 (14%)
Query: 133 KKAER--EEYRKSWSTATSPLGGERPFRSTSMFDMRCEEEAAVQPHSRARQEQLQLINNQ 190
KKA+R EE K + L +R+T + ++ A +Q R + + I Q
Sbjct: 155 KKADRYIEELTKERDALSLEL-----YRNTITNEELKKKNAELQEKLRLAESEKSEI--Q 207
Query: 191 LREEDDKWQDDLARW---KSRRRSVSQDLIKKEEE--------RKKMEKLLAGEDGTSER 239
L ++ K + + A++ + + ++ +++ ++EEE RK+ EK+ E+ E+
Sbjct: 208 LNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQ 267
Query: 240 RKSIKTYREIVQEKERR----ERELHEAYKNARSQE---EAEGILQQYIERFTISEAVLE 292
++ E ++ +E+R E+EL E K R Q+ E E +Q+ E+ E +
Sbjct: 268 EGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMR 327
Query: 293 RLE 295
E
Sbjct: 328 EQE 330
Score = 30.8 bits (68), Expect = 5.8
Identities = 31/164 (18%), Positives = 66/164 (40%), Gaps = 27/164 (16%)
Query: 137 REEYRKSWSTATSPLGGERPFRSTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREEDD 196
RE+ K W E+ R MR +EE + R R+++ ++RE++
Sbjct: 327 REQEEKMWRQEERLWEQEKQMREQEQ-KMRDQEERMWEQDERLREKE-----ERMREQEK 380
Query: 197 KWQDDLARWKSRRRSVSQDLIKKEEE--RKKMEKLLAGEDGTSER--------------- 239
W+ + + R + +++EEE R++ EK+ E+ E+
Sbjct: 381 MWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKE 440
Query: 240 ----RKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQ 279
++ ++ E + E+E + R+ E + + E + +Q
Sbjct: 441 KLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQ 484
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 49.3 bits (116), Expect = 2e-05
Identities = 51/220 (23%), Positives = 98/220 (44%), Gaps = 16/220 (7%)
Query: 606 ERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPF 665
E R+E+ + EQ +ER +K +++ KE+ E+ ++E EERR E R+ E +
Sbjct: 147 EHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARR--EVSAHHR 204
Query: 666 TVSSSSADQLSTSS-SMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESD 724
T+ +D++ S S + + +LG+ R+ K + ++ DLL ++
Sbjct: 205 TMREDYSDKVKASHWSRSPPRPPRERFELGD------GRKPVKEEKMEERDLLSDLQDIS 258
Query: 725 RLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSN--- 781
E K S E + A SG+ + E+ + + E + ++ + + SN
Sbjct: 259 DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE 318
Query: 782 -PTHSSEDVKPKTLPLD---KSINHQIESPSERRKSISGK 817
S+E+V + + D ++ NH + P R SG+
Sbjct: 319 ASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGE 358
Score = 42.7 bits (99), Expect = 0.001
Identities = 39/128 (30%), Positives = 61/128 (47%), Gaps = 19/128 (14%)
Query: 156 PFRSTSMFDMRCEEE---AAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSR---- 208
P+R + R EE+ A P +R+E++ ++ R+E KW+ AR K R
Sbjct: 66 PYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKE--KWKH--ARVKEREHER 121
Query: 209 --RRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKN 266
R QD ++E ER+K ++ A E ER + E ++ K RER++ E K
Sbjct: 122 RKRHREEQDKARREWERQKRREM-AREHSRRERDRL-----EQLERKRERERKMREQQKE 175
Query: 267 ARSQEEAE 274
R Q+E E
Sbjct: 176 QREQKERE 183
Score = 31.6 bits (70), Expect = 3.4
Identities = 29/91 (31%), Positives = 43/91 (47%), Gaps = 7/91 (7%)
Query: 193 EEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQE 252
EEDD + SR+ V +K+E+RK+ K ++ ERR K +RE Q+
Sbjct: 78 EEDDSLAIKPPQQMSRKEKVHH---RKDEKRKEKWKHARVKEREHERR---KRHRE-EQD 130
Query: 253 KERRERELHEAYKNARSQEEAEGILQQYIER 283
K RRE E + + AR E + +ER
Sbjct: 131 KARREWERQKRREMAREHSRRERDRLEQLER 161
Score = 30.4 bits (67), Expect = 7.6
Identities = 35/165 (21%), Positives = 69/165 (41%), Gaps = 17/165 (10%)
Query: 128 APLRKKKAEREEYRKSWSTATSPLGGERPFRSTSMFDMRCEEEAAVQPHSRARQEQLQLI 187
+P R++ + + + S A P ++ R + + E+ H+R ++ + +
Sbjct: 65 SPYRREDSMEDRGEEDDSLAIKP--PQQMSRKEKVHHRKDEKRKEKWKHARVKEREHER- 121
Query: 188 NNQLREEDDK----WQD----DLARWKSRR-RSVSQDLIKKEEERKKMEKLLAGEDGTSE 238
+ REE DK W+ ++AR SRR R + L +K E +KM E +
Sbjct: 122 RKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMR-----EQQKEQ 176
Query: 239 RRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIER 283
R + + R + KER R A+ ++ ++ + + R
Sbjct: 177 REQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSR 221
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 49.3 bits (116), Expect = 2e-05
Identities = 51/220 (23%), Positives = 98/220 (44%), Gaps = 16/220 (7%)
Query: 606 ERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPF 665
E R+E+ + EQ +ER +K +++ KE+ E+ ++E EERR E R+ E +
Sbjct: 157 EHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARR--EVSAHHR 214
Query: 666 TVSSSSADQLSTSS-SMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESD 724
T+ +D++ S S + + +LG+ R+ K + ++ DLL ++
Sbjct: 215 TMREDYSDKVKASHWSRSPPRPPRERFELGD------GRKPVKEEKMEERDLLSDLQDIS 268
Query: 725 RLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSN--- 781
E K S E + A SG+ + E+ + + E + ++ + + SN
Sbjct: 269 DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE 328
Query: 782 -PTHSSEDVKPKTLPLD---KSINHQIESPSERRKSISGK 817
S+E+V + + D ++ NH + P R SG+
Sbjct: 329 ASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGE 368
Score = 37.4 bits (85), Expect = 0.062
Identities = 34/134 (25%), Positives = 58/134 (43%), Gaps = 21/134 (15%)
Query: 156 PFRSTSMFDMRCEEE---AAVQPHSRARQEQLQLINNQLREEDDKWQDDLARW------- 205
P+R + R EE+ A P +R+E++ ++ R+E + A
Sbjct: 66 PYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKCRHHSHSAEGGKHARVK 125
Query: 206 -----KSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERREREL 260
+ +R QD ++E ER+K ++ A E ER + E ++ K RER++
Sbjct: 126 EREHERRKRHREEQDKARREWERQKRREM-AREHSRRERDRL-----EQLERKRERERKM 179
Query: 261 HEAYKNARSQEEAE 274
E K R Q+E E
Sbjct: 180 REQQKEQREQKERE 193
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 49.3 bits (116), Expect = 2e-05
Identities = 51/220 (23%), Positives = 98/220 (44%), Gaps = 16/220 (7%)
Query: 606 ERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPF 665
E R+E+ + EQ +ER +K +++ KE+ E+ ++E EERR E R+ E +
Sbjct: 148 EHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARR--EVSAHHR 205
Query: 666 TVSSSSADQLSTSS-SMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESD 724
T+ +D++ S S + + +LG+ R+ K + ++ DLL ++
Sbjct: 206 TMREDYSDKVKASHWSRSPPRPPRERFELGD------GRKPVKEEKMEERDLLSDLQDIS 259
Query: 725 RLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSN--- 781
E K S E + A SG+ + E+ + + E + ++ + + SN
Sbjct: 260 DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE 319
Query: 782 -PTHSSEDVKPKTLPLD---KSINHQIESPSERRKSISGK 817
S+E+V + + D ++ NH + P R SG+
Sbjct: 320 ASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGE 359
Score = 39.3 bits (90), Expect = 0.016
Identities = 33/125 (26%), Positives = 58/125 (46%), Gaps = 12/125 (9%)
Query: 156 PFRSTSMFDMRCEEE---AAVQPHSRARQEQLQLINNQLREEDDKW---QDDLARWKSRR 209
P+R + R EE+ A P +R+E++ ++ R+E + + + +R
Sbjct: 66 PYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKR 125
Query: 210 RSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARS 269
QD ++E ER+K ++ A E ER + E ++ K RER++ E K R
Sbjct: 126 HREEQDKARREWERQKRREM-AREHSRRERDRL-----EQLERKRERERKMREQQKEQRE 179
Query: 270 QEEAE 274
Q+E E
Sbjct: 180 QKERE 184
Score = 30.0 bits (66), Expect = 10.0
Identities = 30/128 (23%), Positives = 57/128 (44%), Gaps = 15/128 (11%)
Query: 166 RCEEEAAVQPHSRARQEQLQLINNQL-REEDDK----WQD----DLARWKSRR-RSVSQD 215
R +E+ + H+R ++++ + + REE DK W+ ++AR SRR R +
Sbjct: 100 RKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQ 159
Query: 216 LIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEG 275
L +K E +KM E +R + + R + KER R A+ ++ ++
Sbjct: 160 LERKRERERKMR-----EQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDK 214
Query: 276 ILQQYIER 283
+ + R
Sbjct: 215 VKASHWSR 222
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 49.3 bits (116), Expect = 2e-05
Identities = 51/220 (23%), Positives = 98/220 (44%), Gaps = 16/220 (7%)
Query: 606 ERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPF 665
E R+E+ + EQ +ER +K +++ KE+ E+ ++E EERR E R+ E +
Sbjct: 125 EHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARR--EVSAHHR 182
Query: 666 TVSSSSADQLSTSS-SMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESD 724
T+ +D++ S S + + +LG+ R+ K + ++ DLL ++
Sbjct: 183 TMREDYSDKVKASHWSRSPPRPPRERFELGD------GRKPVKEEKMEERDLLSDLQDIS 236
Query: 725 RLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSN--- 781
E K S E + A SG+ + E+ + + E + ++ + + SN
Sbjct: 237 DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE 296
Query: 782 -PTHSSEDVKPKTLPLD---KSINHQIESPSERRKSISGK 817
S+E+V + + D ++ NH + P R SG+
Sbjct: 297 ASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGE 336
Score = 37.4 bits (85), Expect = 0.062
Identities = 34/136 (25%), Positives = 59/136 (43%), Gaps = 23/136 (16%)
Query: 156 PFRSTSMFDMRCEEE---AAVQPHSRARQEQLQLINNQLREEDDKWQDDLARW------- 205
P+R + R EE+ A P +R+E++ ++ R+E + + A
Sbjct: 32 PYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGKHARVK 91
Query: 206 -------KSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRER 258
+ +R QD ++E ER+K ++ A E ER + E ++ K RER
Sbjct: 92 EKEREHERRKRHREEQDKARREWERQKRREM-AREHSRRERDRL-----EQLERKRERER 145
Query: 259 ELHEAYKNARSQEEAE 274
++ E K R Q+E E
Sbjct: 146 KMREQQKEQREQKERE 161
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 49.3 bits (116), Expect = 2e-05
Identities = 51/220 (23%), Positives = 98/220 (44%), Gaps = 16/220 (7%)
Query: 606 ERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPF 665
E R+E+ + EQ +ER +K +++ KE+ E+ ++E EERR E R+ E +
Sbjct: 114 EHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARR--EVSAHHR 171
Query: 666 TVSSSSADQLSTSS-SMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESD 724
T+ +D++ S S + + +LG+ R+ K + ++ DLL ++
Sbjct: 172 TMREDYSDKVKASHWSRSPPRPPRERFELGD------GRKPVKEEKMEERDLLSDLQDIS 225
Query: 725 RLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSN--- 781
E K S E + A SG+ + E+ + + E + ++ + + SN
Sbjct: 226 DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE 285
Query: 782 -PTHSSEDVKPKTLPLD---KSINHQIESPSERRKSISGK 817
S+E+V + + D ++ NH + P R SG+
Sbjct: 286 ASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGE 325
Score = 39.3 bits (90), Expect = 0.016
Identities = 33/125 (26%), Positives = 58/125 (46%), Gaps = 12/125 (9%)
Query: 156 PFRSTSMFDMRCEEE---AAVQPHSRARQEQLQLINNQLREEDDKW---QDDLARWKSRR 209
P+R + R EE+ A P +R+E++ ++ R+E + + + +R
Sbjct: 32 PYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKR 91
Query: 210 RSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARS 269
QD ++E ER+K ++ A E ER + E ++ K RER++ E K R
Sbjct: 92 HREEQDKARREWERQKRREM-AREHSRRERDRL-----EQLERKRERERKMREQQKEQRE 145
Query: 270 QEEAE 274
Q+E E
Sbjct: 146 QKERE 150
Score = 30.0 bits (66), Expect = 10.0
Identities = 30/128 (23%), Positives = 57/128 (44%), Gaps = 15/128 (11%)
Query: 166 RCEEEAAVQPHSRARQEQLQLINNQL-REEDDK----WQD----DLARWKSRR-RSVSQD 215
R +E+ + H+R ++++ + + REE DK W+ ++AR SRR R +
Sbjct: 66 RKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQ 125
Query: 216 LIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEG 275
L +K E +KM E +R + + R + KER R A+ ++ ++
Sbjct: 126 LERKRERERKMR-----EQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDK 180
Query: 276 ILQQYIER 283
+ + R
Sbjct: 181 VKASHWSR 188
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 49.3 bits (116), Expect = 2e-05
Identities = 51/220 (23%), Positives = 98/220 (44%), Gaps = 16/220 (7%)
Query: 606 ERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPF 665
E R+E+ + EQ +ER +K +++ KE+ E+ ++E EERR E R+ E +
Sbjct: 159 EHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARR--EVSAHHR 216
Query: 666 TVSSSSADQLSTSS-SMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESD 724
T+ +D++ S S + + +LG+ R+ K + ++ DLL ++
Sbjct: 217 TMREDYSDKVKASHWSRSPPRPPRERFELGD------GRKPVKEEKMEERDLLSDLQDIS 270
Query: 725 RLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSN--- 781
E K S E + A SG+ + E+ + + E + ++ + + SN
Sbjct: 271 DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE 330
Query: 782 -PTHSSEDVKPKTLPLD---KSINHQIESPSERRKSISGK 817
S+E+V + + D ++ NH + P R SG+
Sbjct: 331 ASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGE 370
Score = 37.4 bits (85), Expect = 0.062
Identities = 34/136 (25%), Positives = 59/136 (43%), Gaps = 23/136 (16%)
Query: 156 PFRSTSMFDMRCEEE---AAVQPHSRARQEQLQLINNQLREEDDKWQDDLARW------- 205
P+R + R EE+ A P +R+E++ ++ R+E + + A
Sbjct: 66 PYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGKHARVK 125
Query: 206 -------KSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRER 258
+ +R QD ++E ER+K ++ A E ER + E ++ K RER
Sbjct: 126 EKEREHERRKRHREEQDKARREWERQKRREM-AREHSRRERDRL-----EQLERKRERER 179
Query: 259 ELHEAYKNARSQEEAE 274
++ E K R Q+E E
Sbjct: 180 KMREQQKEQREQKERE 195
Score = 30.4 bits (67), Expect = 7.6
Identities = 51/258 (19%), Positives = 97/258 (37%), Gaps = 31/258 (12%)
Query: 27 DCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVVLRGSSDGRGSDSESDLPHR 86
D W + D + + R + + + R + + D +G D ++ R
Sbjct: 6 DSWKVKTLDEILQEKKRRKEQEEKAEI--KRLKNSDDRDSKRDSLEEGELRDHRMEITIR 63
Query: 87 KLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAEREEYRKSWST 146
P ++D M R GE ++ P + ++ V +K+ E+ +R
Sbjct: 64 NSPYRREDSMEDR----GEEDDSLAIKP--PQQMSRKEKVHHRKDEKRKEKRRHRSH--- 114
Query: 147 ATSPLGGERPFRSTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWK 206
S GG+ E+E + R R+EQ + RE + + + ++AR
Sbjct: 115 --SAEGGKHARVK--------EKEREHERRKRHREEQ----DKARREWERQKRREMAREH 160
Query: 207 SRR-RSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYK 265
SRR R + L +K E +KM E +R + + R + KER R A+
Sbjct: 161 SRRERDRLEQLERKRERERKMR-----EQQKEQREQKERERRAEERRKEREARREVSAHH 215
Query: 266 NARSQEEAEGILQQYIER 283
++ ++ + + R
Sbjct: 216 RTMREDYSDKVKASHWSR 233
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 48.9 bits (115), Expect = 2e-05
Identities = 132/648 (20%), Positives = 267/648 (41%), Gaps = 86/648 (13%)
Query: 130 LRKKKAEREEYRKSWSTATSPLGGERPFRSTSMFDMRCEEEAAVQPHSRARQEQLQLINN 189
L +++ + E +K + L +R S + EEE +Q +E+L
Sbjct: 1735 LNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQ-----EKEKLAQHKE 1789
Query: 190 QLREEDDKW---QDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTY 246
++ EE+++ ++ L K + + I EE K + +L + ++ +K++
Sbjct: 1790 KMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQE 1849
Query: 247 RE-IVQEKER----RERELHEAYKNARSQEEA---EGILQQYIERFTIS-EAVLERLEM- 296
+E + Q KE +ER H + + + + IL Q E+ T E V+++ E
Sbjct: 1850 KEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKL 1909
Query: 297 ----PKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARAS-VLDTSM 351
K+++ S + MK ++++ K E IA+ L+ M
Sbjct: 1910 AETEKKLVQVEDSLAKKQEKLAQEK--MKLALEKAMVQGKKRLRGELDIAKEEKALNLEM 1967
Query: 352 SAGSGSPSKTVTPKAVPML--TPKPYSQPKNSQDVLKTFK----VDGKVSVNGETVHREE 405
+ + V K TP+ Q K +Q + F+ ++ K+ ++ + + E
Sbjct: 1968 KRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKILLHEDRILAME 2027
Query: 406 EKERECPTVAPAH-SLTKSQMF--EGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAA 462
E E +A T+ Q +G ++ + +L + S+ K N + + L
Sbjct: 2028 ESE-----IAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNKILKALQK 2082
Query: 463 TTEKTEPNSQEDKNDGG-------KSRKGNIELASSEPQHFT-----TTVTRCSPTVAFV 510
T +QE+ K R+ +IE + + + + + +T+ +A
Sbjct: 2083 LTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLARK 2142
Query: 511 EFPSSPQLKNDVSEEKDQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLD----K 566
+ + +++ +++E+ + E++++ K V+ + E E PFL K
Sbjct: 2143 QRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEV---IPFLKRRWRK 2199
Query: 567 MPEANQLHLPN--LNSQVDSPSSEK--SPVMTPF-----KFWAWDPEEERRRQEKWQQEQ 617
EA + P +SQVD SE+ S M K + EEE R+E+ ++E+
Sbjct: 2200 RKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREE 2259
Query: 618 ERLLQERYQK--------------EQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVV 663
E + +E ++ E++K K++ EK ++EV+E+E + E+E + E+
Sbjct: 2260 EEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEE-- 2317
Query: 664 PFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQG 711
T S S ++ S S+ E +I Q + Q++R +KS +G
Sbjct: 2318 --TESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQR-RKSLRG 2362
Score = 38.5 bits (88), Expect = 0.028
Identities = 20/60 (33%), Positives = 39/60 (65%), Gaps = 3/60 (5%)
Query: 604 EEERRRQEKWQQEQERLLQERYQKEQDKLKEE---WEKAQKEVEEEERRYYEEERKIIED 660
E+++ + E+W+Q E +L + +++Q K +EE E+ +E EE+E++ EE+R I E+
Sbjct: 1512 EDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEE 1571
Score = 36.6 bits (83), Expect = 0.11
Identities = 34/147 (23%), Positives = 64/147 (43%), Gaps = 20/147 (13%)
Query: 522 VSEEKDQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLP----- 576
V+ E+++ + +V+ +L+QKV + P+ E L + + E +L
Sbjct: 1672 VAREEEKLAKKGGKLAEVKNILAQKV--EELPQREQNLDWQEKELAQELEELEWDMEELS 1729
Query: 577 ----NLNSQVDSPSSEKSPVMTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKL 632
LN + EK + + AW E+ + K QE+E L+QE
Sbjct: 1730 WKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQE--------- 1780
Query: 633 KEEWEKAQKEVEEEERRYYEEERKIIE 659
KE+ + ++++ EEE R + ++IE
Sbjct: 1781 KEKLAQHKEKMPEEEERLGRKREQLIE 1807
Score = 36.6 bits (83), Expect = 0.11
Identities = 140/767 (18%), Positives = 283/767 (36%), Gaps = 103/767 (13%)
Query: 116 LPNKSNQTAYVPAPLRKKKAEREEYRKSWSTATSPLGGERPFRSTSMFDMRCEEEAAVQP 175
L K + A V L +K E + ++ L E M ++ +EE Q
Sbjct: 1679 LAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQE 1738
Query: 176 HSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEER--KKMEKLLAGE 233
+ +E+ +L EE WQ + + + + ++L+ +E+E+ + EK+ E
Sbjct: 1739 EGKLVEEKKKLAEE---EEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEE 1795
Query: 234 DGTSERRKS-IKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLE 292
+ +R+ I+ ++ Q++ER + E KN + + + Q E+ +++
Sbjct: 1796 ERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQ---EKKNLAQ---- 1848
Query: 293 RLEMPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMS 352
E K+ +R + N + + ++ + K A VE + +
Sbjct: 1849 --EKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKK 1906
Query: 353 AGSGSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECP 412
K + + + + + L+ V GK + GE +EEK
Sbjct: 1907 EKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEK----- 1961
Query: 413 TVAPAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPN-- 470
A +L ++ E R+ L + +K V QEL E
Sbjct: 1962 ----ALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKIL 2017
Query: 471 SQEDK---NDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKD 527
ED+ + + KG +E + FV+ Q K + K
Sbjct: 2018 LHEDRILAMEESEIAKGKLEFTRGQR--------------IFVQ----GQRKLAKASRKL 2059
Query: 528 QKKPE--NEMSGKVELVLS--QKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVD 583
KK E ++ K+ +L QK+ + + + + + + + L S++D
Sbjct: 2060 IKKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLD 2119
Query: 584 SPS---SEKSPVMTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQ 640
SEK +T D ++ R+Q K + R++ KE+ +EE + A+
Sbjct: 2120 IKEWDFSEKRSELTK------DEKKLARKQRKLANKMRRMI----NKEEKMTEEESKLAR 2169
Query: 641 KEVE-----EEERRYYEEE-----------RKIIEDTVVPFTVSSSSADQLSTSSSMTEG 684
K E EEE EEE RK + P SS D++ + +E
Sbjct: 2170 KHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEE 2229
Query: 685 -SGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESDRLEEKGSLTEGALAHSGNP 743
+++++ +++ ++ + ++ + ++ E +R EE+ EG
Sbjct: 2230 MESLLDELEKQESLSSEEEEEREEEEEREEEE--VREEEEERKEEE----EG----EEKQ 2279
Query: 744 VSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQ-NQQTSNPTHSSEDVKPKTLPLDKSINH 802
V K E + E ++ ++ + + + S E+ + ++ L++ ++
Sbjct: 2280 VEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDR 2339
Query: 803 ---------QIESPSERRKSISGKKLCSSC--GLPLGKGAAMIIETL 838
Q + +RRKS+ G++ S G+P GKG A+ + L
Sbjct: 2340 EKEILKKEKQFKLQEQRRKSLRGRERVLSILRGVPHGKGRAIRLGVL 2386
Score = 35.8 bits (81), Expect = 0.18
Identities = 43/175 (24%), Positives = 77/175 (44%), Gaps = 23/175 (13%)
Query: 578 LNSQVDSPSSEKSPVMTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWE 637
L +V EK +T EE+R QE + + R+ ++R + E+ + +EE +
Sbjct: 1546 LEEEVSREGEEKEQQVT---------EEQRHIQE--EHKWARIHRKRARAEKKRAQEERK 1594
Query: 638 KAQKE--VEEEERRYYEEERKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGN 695
AQ+E + +EER+ +EERK+ + V ++ + + T+ +
Sbjct: 1595 LAQEEEKLAQEERQLAQEERKLAQAYV---KITQDDREMAQAEGKFAQKEETLAQ----- 1646
Query: 696 CQDEKQDRRWKKSFQGDDSDLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHE 750
+ EK + +K Q L K + R EEK + G LA N +++ V E
Sbjct: 1647 -RGEKLSQEAEKLAQ-KRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEE 1699
Score = 32.7 bits (73), Expect = 1.5
Identities = 24/76 (31%), Positives = 37/76 (48%), Gaps = 11/76 (14%)
Query: 597 KFW-AWDPEEERR---RQEKWQQEQERLLQERYQKEQDKL------KEEWEKAQKEVEEE 646
K W AW E E+R +EK Q E+L E ++DK K+ WE + +
Sbjct: 1476 KSWKAWKEEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSS-KSK 1534
Query: 647 ERRYYEEERKIIEDTV 662
E++Y +EE +E+ V
Sbjct: 1535 EQQYKDEEEVTLEEEV 1550
Score = 31.6 bits (70), Expect = 3.4
Identities = 102/556 (18%), Positives = 207/556 (37%), Gaps = 82/556 (14%)
Query: 169 EEAAVQPHSRARQ--EQLQLINNQLREEDD-KWQDDLARWKSRRRSVSQDLIKKEEERKK 225
E+ +Q + Q E+L L+E+ KW++ W++ S S++ K+EE
Sbjct: 1486 EKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVT 1545
Query: 226 MEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFT 285
+E+ ++ E E++ V E++R +E H+ + R + AE Q +
Sbjct: 1546 LEEEVSREGEEKEQQ---------VTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLA 1596
Query: 286 ISEAVLERLEMPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARAS 345
E L + E E + + +D R+ + KF ET R
Sbjct: 1597 QEEEKLAQEERQLAQEERKLAQAYVKITQDD-------REMAQAEGKFAQKEETLAQRGE 1649
Query: 346 VLDTSMSAGSGSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKV----SVNGETV 401
L + K K +++ K K GK+ ++ + V
Sbjct: 1650 KLSQEAEKLAQKRKKLAK------------KWEKVAREEEKLAKKGGKLAEVKNILAQKV 1697
Query: 402 HREEEKERECPTVAPAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELA 461
++E+ + ++ + + EL Q+ G + KK + LA
Sbjct: 1698 EELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALA 1757
Query: 462 ATTEKT------------------------EPNSQEDKNDGGKSRKGNIE----LASSEP 493
EK + E++ G+ R+ IE LA
Sbjct: 1758 WQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRE 1817
Query: 494 QHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQ--KKPENEMSGKVELVLSQK-VVKP 550
+ + + + + Q K ++++EK++ ++ EN + K L S+K +V+
Sbjct: 1818 RWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQV 1877
Query: 551 KSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTPFKFWAWDPEEERRRQ 610
K+ + + L ++ E L + ++ +K + K + ++Q
Sbjct: 1878 KN---KLGMFNKILAQVEE-------KLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQ 1927
Query: 611 EKWQQEQERL-LQERYQKEQDKLKEEWE--KAQKEVEEEERRYYEEERKIIEDTVVPFTV 667
EK QE+ +L L++ + + +L+ E + K +K + E +R EE+ +++E T+
Sbjct: 1928 EKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKALNLEMKRLAEEKMRLVEGKE---TL 1984
Query: 668 SSSSADQLSTSSSMTE 683
S + S MT+
Sbjct: 1985 SKGETPETSRQRKMTQ 2000
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 48.5 bits (114), Expect = 3e-05
Identities = 95/475 (20%), Positives = 195/475 (41%), Gaps = 54/475 (11%)
Query: 60 QTPSPDVV---LRGSSDGRGS--DSESDLPHRKL-PDVKKDDMSARRTSHGEPKSAVPFN 113
Q P+P V L+ +D R S + LP + + + K++ + +H E V
Sbjct: 524 QVPTPVVKQTKLKQRADSRESLKPAAKPLPSKSVRKESKEETPEVTKVNHVEKPPKVESK 583
Query: 114 QYLPNKSNQ---TAYVPAPLRKKKAEREEYRKSWSTATSPLGGERPFRSTSMFDMRCEEE 170
+ + K ++ T P+ K+ +EE SP+ E + + + +E
Sbjct: 584 EKVMVKKDKPIKTETKPSVTEKEVPSKEE--------PSPVKAEVAEKQATDVKPKAAKE 635
Query: 171 AAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLL 230
V+ ++ + E +EE +K + ++A+ + + ++ KKEE +K+++K +
Sbjct: 636 KTVKKETKVKPEDK-------KEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEI 688
Query: 231 AGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFT--ISE 288
E+ +++ K +KE ++ E E K + ++ L + ++ + +SE
Sbjct: 689 KKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSSTPLSE 748
Query: 289 AVLERLEMPKILERSHSTEPN--LSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASV 346
A PK+ ++ S + + + + +K ++++ A V T A+V
Sbjct: 749 AKKPAALKPKVPKKEESVKKDSVAAGKPKEKGKIKVIKKEGKAAEAVAAAVGTGATTAAV 808
Query: 347 LDTSMSAGSGSPSKTVTPKAVPMLTP----KPYSQPKNSQ-DVLKTFKVDGKVSVNGETV 401
+ + A G P+K + + M +P K + + K + DV K K ++ + E +
Sbjct: 809 MAAAGIAAIG-PAKELEAERSLMSSPEDLTKDFEELKAEEVDVTKDIKPQLELIEDEEKL 867
Query: 402 HREE-------EKEREC---PTVAPAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIK 451
E +KERE P +P +T + EG +P EL+ +I+
Sbjct: 868 KETEPVEAYVIQKEREVTKGPAESPDEGITTT---EGEGECEQTPEELEPVEKQGVDDIE 924
Query: 452 KPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQHFTTTVTRCSPT 506
K E A E +E E+K + ++ E +H + ++ SPT
Sbjct: 925 K---FEDEGAGFEESSETGDYEEKAETEEAE----EPEEDGEEHVCVSASKHSPT 972
Score = 32.3 bits (72), Expect = 2.0
Identities = 70/333 (21%), Positives = 134/333 (40%), Gaps = 38/333 (11%)
Query: 492 EPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQK-KPENEMSGKVELVLSQKV--- 547
E + T VT+ V VE P + K V +KD+ K E + S + V S++
Sbjct: 560 ESKEETPEVTK----VNHVEKPPKVESKEKVMVKKDKPIKTETKPSVTEKEVPSKEEPSP 615
Query: 548 VKPKSPEPEATLTFPFLDK---MPEANQLHLPNLNSQVDSPSSE--KSPVMTPFKFWAWD 602
VK + E +AT P K + + ++ + + + P E K TP K
Sbjct: 616 VKAEVAEKQATDVKPKAAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKP 675
Query: 603 PEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTV 662
+EE +++ K + ++E + + + +++ +E +K K+ E++E + E+E K
Sbjct: 676 KKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPK------ 729
Query: 663 VPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRE 722
+ D +S+ ++E K + K++ KK DS K +E
Sbjct: 730 --KEIKKLPKDAKKSSTPLSEA----KKPAALKPKVPKKEESVKK-----DSVAAGKPKE 778
Query: 723 SDR---LEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQT 779
+ ++++G E A G + + AG G +L + S
Sbjct: 779 KGKIKVIKKEGKAAEAVAAAVGTGATTAA-----VMAAAGIAAIGPAKELEAERSLMSSP 833
Query: 780 SNPTHSSEDVKPKTLPLDKSINHQIESPSERRK 812
+ T E++K + + + K I Q+E + K
Sbjct: 834 EDLTKDFEELKAEEVDVTKDIKPQLELIEDEEK 866
Score = 32.0 bits (71), Expect = 2.6
Identities = 30/148 (20%), Positives = 67/148 (45%), Gaps = 6/148 (4%)
Query: 515 SPQLKNDVSEEKDQKKPENEMSGKVELVLSQKVV----KPKSPEPEATLTFPFLDKMPEA 570
S ++ + EE + N + ++ +KV+ KP E + ++T + E
Sbjct: 554 SKSVRKESKEETPEVTKVNHVEKPPKVESKEKVMVKKDKPIKTETKPSVTEKEVPSKEEP 613
Query: 571 NQLHLPNLNSQVDSPSSEKSPVMTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQD 630
+ + Q + + T K PE+++ +EK ++E + + K+++
Sbjct: 614 SPVKAEVAEKQATDVKPKAAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEE 673
Query: 631 KLKEEWEK--AQKEVEEEERRYYEEERK 656
K K+E K +KE+++EE++ ++E K
Sbjct: 674 KPKKEEVKKEVKKEIKKEEKKEPKKEVK 701
>gi|15149467 caldesmon 1 isoform 3 [Homo sapiens]
Length = 564
Score = 48.5 bits (114), Expect = 3e-05
Identities = 124/612 (20%), Positives = 230/612 (37%), Gaps = 93/612 (15%)
Query: 200 DDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERE 259
DD R + RR K+EE R + E++ + E + + R QE+ R+++E
Sbjct: 2 DDFERRRELRRQ------KREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQE 55
Query: 260 LHEAYKNARSQEE--AEGILQQYIERFTISEAVLERLEMPKILERSHSTEPNLSSFLNDP 317
E+ Q E A+ + + T + +E + LER E L +
Sbjct: 56 -EESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQE- 113
Query: 318 NPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKPYSQ 377
RQ+ P TI AS+ S + + T K + + +
Sbjct: 114 ---ALERQKEFDP---------TITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYE 161
Query: 378 PKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVAPAHSLTKSQMFEGVARVHGSPL 437
+ ++ V K+++ + E ++EKE E S+ ++Q E +V
Sbjct: 162 IEETETVTKSYQKNDWRDAE-ENKKEDKEKEEEEEEKPKRGSIGENQGEEKGTKVQAKRE 220
Query: 438 ELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQHFT 497
+L++D KP +E+ K + +E+ +KG E+ S + T
Sbjct: 221 KLQED---------KPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMT 271
Query: 498 TTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEMSGKVELVL-------SQKVVKP 550
+ T S P + V ++ + P+ E ++E + S++ K
Sbjct: 272 HKLKHTENTF------SRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKL 325
Query: 551 KSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTPFKFWAWDPEEERRRQ 610
K + EA L L K E E+ V+ + EE+RR+Q
Sbjct: 326 KQKQQEAALELEELKKKRE------------------ERRKVL--------EEEEQRRKQ 359
Query: 611 EKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTVSSS 670
E E +R L+E ++E+ +LKEE E+ + E E+ ++ E+ + FT S
Sbjct: 360 E----EADRKLRE--EEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGS 413
Query: 671 S------ADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESD 724
S A+ L+ S + G + ++ + + D + + ++ + +G S K SD
Sbjct: 414 SLKIEERAEFLNKSVQKSSGVKSTHQAAIVSKIDSRLE-QYTSAIEGTKSAKPTKPAASD 472
Query: 725 -RLEEKGSLTEGALAHSGN----PVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQT 779
+ +G ++ GN P + G + G N L + P N+
Sbjct: 473 LPVPAEGVRNIKSMWEKGNVFSSPTAAGTPNKETAGLKVGV-SSRINEWLTKTPDGNK-- 529
Query: 780 SNPTHSSEDVKP 791
+P D++P
Sbjct: 530 -SPAPKPSDLRP 540
Score = 40.4 bits (93), Expect = 0.007
Identities = 50/262 (19%), Positives = 101/262 (38%), Gaps = 45/262 (17%)
Query: 602 DPEEERRRQEKWQQEQERLLQER--YQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIE 659
D E RR + ++E+ RL ER YQ+ D +E + ++ +E R +EE + +
Sbjct: 2 DDFERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQ 61
Query: 660 DT-VVPFTVSSSSADQ---LSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGD--- 712
T V +S D+ +T+++ EG ++ ++E++ +R +++ +
Sbjct: 62 VTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEF 121
Query: 713 -----DSDLLLKTR----------------------ESDRLEEKGSLTEGALAHSGNPVS 745
D+ L L +R E +EE ++T+ +
Sbjct: 122 DPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAE 181
Query: 746 KGVHEDHQLDTEA---------GAPHCGTNPQLAQDPSQNQQTSNPTHSSEDVKPKTLPL 796
+ ED + + E G Q + Q PT E++K + +
Sbjct: 182 ENKKEDKEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKK 241
Query: 797 DKSINHQIESPSERRKSISGKK 818
DK +++S +R+K + K
Sbjct: 242 DKEPKEEVKSFMDRKKGFTEVK 263
Score = 37.0 bits (84), Expect = 0.082
Identities = 51/243 (20%), Positives = 89/243 (36%), Gaps = 27/243 (11%)
Query: 573 LHLPNLNSQVDSPSSEKSPVMTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKL 632
L LP+ Q D+ +E + E+ RQE+++ E+ + + YQK +
Sbjct: 130 LSLPSRRMQNDTAENETTE----------KEEKSESRQERYEIEETETVTKSYQKNDWRD 179
Query: 633 KEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKID 692
EE +K KE EE EEE K ++ + + E T K +
Sbjct: 180 AEENKKEDKEKEE------EEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEE 233
Query: 693 LGN--CQDEKQDRRWKKSFQGDDSDLL-LKTRESDRLEEKGSLTEGALAHSGNPVSKGVH 749
+ + + +K+ + KSF +K++ + + K TE + G S
Sbjct: 234 IKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTK 293
Query: 750 EDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSNPTHSSEDVKPKTLPLDKSINHQIESPSE 809
E GAP +L + + +T + E +K K + + E
Sbjct: 294 E------AEGAPQVEAGKRLEELRRRRGETE--SEEFEKLKQKQQEAALELEELKKKREE 345
Query: 810 RRK 812
RRK
Sbjct: 346 RRK 348
Score = 36.2 bits (82), Expect = 0.14
Identities = 29/154 (18%), Positives = 67/154 (43%), Gaps = 13/154 (8%)
Query: 130 LRKKKAEREEYRKSWSTATSPLGGERPFRSTSMFDMRCEEEAAVQPHSRARQEQLQLINN 189
L++ ++E+ + + A+ L R T+ + +EE + R E+ + +
Sbjct: 111 LQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTK 170
Query: 190 QLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREI 249
++ D W+ + +D K+EEE +K ++ GE+ E+ ++ RE
Sbjct: 171 SYQKND---------WRDAEENKKEDKEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREK 221
Query: 250 VQEK----ERRERELHEAYKNARSQEEAEGILQQ 279
+QE ++ E + + K+ +EE + + +
Sbjct: 222 LQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDR 255
Score = 35.4 bits (80), Expect = 0.24
Identities = 50/282 (17%), Positives = 114/282 (40%), Gaps = 30/282 (10%)
Query: 1 MDSERQVKDTDDIESPKRSIRDSGYIDCWDSERSDSLSPP---RHGRDDSFDSLDSFGSR 57
+ S R DT + E+ ++ + + ++ E +++++ RD + +
Sbjct: 132 LPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKE 191
Query: 58 SRQTPSPDVVLRGSSDGRGSDSESDLPHRKL----PDVKKDDMSARRTSHG-EPKSAVPF 112
+ P G + G ++ KL P KK+++ + EPK V
Sbjct: 192 EEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEV-- 249
Query: 113 NQYLPNKSNQTAYVPAPLRKKKAEREEYRKSWSTATSPLGGERPFRSTSMFDMRCEEEAA 172
++ K T ++ + E ++ + T G R T E E A
Sbjct: 250 KSFMDRKKGFTE-----VKSQNGEFMTHKLKHTENTFSRPGGRASVDTK------EAEGA 298
Query: 173 VQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAG 232
Q + R E+L+ R + ++ + K +++ + +L + +++R++ K+L
Sbjct: 299 PQVEAGKRLEELR------RRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEE 352
Query: 233 EDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAE 274
E+ +RRK + R++ +E+E+R + + A + E+ +
Sbjct: 353 EE---QRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQ 391
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 48.1 bits (113), Expect = 4e-05
Identities = 31/134 (23%), Positives = 66/134 (49%), Gaps = 1/134 (0%)
Query: 522 VSEEKDQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQ 581
+ E++++++ + E K E + ++ K + E + + + E Q + Q
Sbjct: 593 IREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQ 652
Query: 582 VDSPSSEKSPVMTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQK 641
+ E+ M + W EE+ R QEK +EQE ++E+ + Q++ ++ WE+ +K
Sbjct: 653 -EEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEK 711
Query: 642 EVEEEERRYYEEER 655
E+EE+ +EE+
Sbjct: 712 MCEQEEKMQEQEEK 725
Score = 47.0 bits (110), Expect = 8e-05
Identities = 36/148 (24%), Positives = 77/148 (52%), Gaps = 5/148 (3%)
Query: 164 DMRCEEEAAVQPHSRARQE-QLQLINNQLREEDDKWQDDLAR-WKSRRRSVSQDLIKKEE 221
+ R EEE + R QE ++ ++RE+++K ++ + W+ + Q+ I++EE
Sbjct: 411 EKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEE 470
Query: 222 ERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAY--KNARSQEEAEGILQQ 279
+R++ E++ E+ E ++ I +E + E+E + R+ E + + +E+ E I +Q
Sbjct: 471 KRQEQEEMWRQEEKIHE-QEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQ 529
Query: 280 YIERFTISEAVLERLEMPKILERSHSTE 307
+ + E + E+ EM + E+ H E
Sbjct: 530 EEKMWRQEEKIREQEEMWREEEKMHEQE 557
Score = 46.2 bits (108), Expect = 1e-04
Identities = 26/72 (36%), Positives = 44/72 (61%), Gaps = 4/72 (5%)
Query: 588 EKSPVMTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQK--EQDKLKEEWEKAQKE--V 643
EK M + W+ EE+ RRQE+ E+E ++E +K EQ+K++E+ EK Q+E +
Sbjct: 360 EKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKI 419
Query: 644 EEEERRYYEEER 655
E+E+R +E +
Sbjct: 420 REQEKRQEQEAK 431
Score = 43.9 bits (102), Expect = 7e-04
Identities = 30/150 (20%), Positives = 66/150 (44%), Gaps = 6/150 (4%)
Query: 130 LRKKKAEREEYRKSWSTATSPLGGERPFRSTSMFDMRCEEEAAVQPHSRARQEQLQLINN 189
+R+++ +E+ K W E R R EE+ + + R+E+ +
Sbjct: 419 IREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEK--IHEQEKIREEEKRQEQE 476
Query: 190 QLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREI 249
++ +++K + W+ + + Q+ E+ RK+ EK+ E+ E+ + I+ E
Sbjct: 477 EMWRQEEKIHEQEEIWRQKEKMHEQE----EKIRKQEEKVWRQEEKIREQEEKIREQEEK 532
Query: 250 VQEKERRERELHEAYKNARSQEEAEGILQQ 279
+ +E + RE E ++ E E I ++
Sbjct: 533 MWRQEEKIREQEEMWREEEKMHEQEKIWEE 562
Score = 42.7 bits (99), Expect = 0.001
Identities = 37/150 (24%), Positives = 72/150 (48%), Gaps = 10/150 (6%)
Query: 137 REEYRKSWSTATSPLGGERPFRSTSMFDMRCEEEAAVQPHSRARQE-QLQLINNQLREED 195
RE+ K W E +R E+E + R QE ++ ++RE++
Sbjct: 527 REQEEKMWRQEEKIREQEEMWREEEKMH---EQEKIWEEEKRQEQEDKMWRQEEKIREQE 583
Query: 196 DK-W-QDDLARWKSRRRSVSQDLIKKEEE--RKKMEKLLAGEDGTSERRKSIKTYREIVQ 251
+K W Q++ R + +R ++ + K+EE R++ EK+ E+ E+ + I+ E+ Q
Sbjct: 584 EKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQ 643
Query: 252 EKERR--ERELHEAYKNARSQEEAEGILQQ 279
E+E + E+E + + QE+ E + +Q
Sbjct: 644 EQEEKMGEQEEKMCEQEEKMQEQEETMWRQ 673
Score = 42.4 bits (98), Expect = 0.002
Identities = 30/135 (22%), Positives = 61/135 (45%), Gaps = 9/135 (6%)
Query: 601 WDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQK------EVEEEERRYYEEE 654
W EE+ R QE+ QE ++E+ +K Q++ ++ W++ +K +++E+E + E+E
Sbjct: 573 WRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQE 632
Query: 655 RKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDS 714
KI E + +Q M E M + + + E++ R +K + +
Sbjct: 633 EKIREQEEMTQEQEEKMGEQ---EEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEE 689
Query: 715 DLLLKTRESDRLEEK 729
+ + EEK
Sbjct: 690 KIREQEEMMQEQEEK 704
Score = 42.0 bits (97), Expect = 0.003
Identities = 18/60 (30%), Positives = 39/60 (65%), Gaps = 5/60 (8%)
Query: 601 WDPEEERRRQEK-WQQEQERLLQERYQKEQDKLKEE----WEKAQKEVEEEERRYYEEER 655
W EE+ QEK W++E+ + +++ ++++K++E+ W + +K E+EE+R +EE+
Sbjct: 547 WREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEK 606
Score = 41.6 bits (96), Expect = 0.003
Identities = 28/141 (19%), Positives = 70/141 (49%), Gaps = 7/141 (4%)
Query: 601 WDPEEERRRQEK-WQQEQE-RLLQERYQKEQDKLKEEWEKAQKEVE---EEERRYYEEER 655
W+ E+ + +++K W+QE++ R +E+ ++++K++E+ EK Q++ E ++E + E+E
Sbjct: 560 WEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEE 619
Query: 656 KIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNK--IDLGNCQDEKQDRRWKKSFQGDD 713
KI E +Q + E G + + E+++ W++ + +
Sbjct: 620 KIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIRE 679
Query: 714 SDLLLKTRESDRLEEKGSLTE 734
+ ++ +E E++ + E
Sbjct: 680 QEKKIREQEEKIREQEEMMQE 700
Score = 40.4 bits (93), Expect = 0.007
Identities = 22/61 (36%), Positives = 39/61 (63%), Gaps = 7/61 (11%)
Query: 601 WDPEEERRRQEK--WQQEQERLLQER--YQKEQDKLKEE---WEKAQKEVEEEERRYYEE 653
W+ EE+ RRQE+ W++E++ QE ++KE+ ++E WEK +K E EE+ + +E
Sbjct: 345 WEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQE 404
Query: 654 E 654
+
Sbjct: 405 K 405
Score = 40.4 bits (93), Expect = 0.007
Identities = 35/173 (20%), Positives = 79/173 (45%), Gaps = 9/173 (5%)
Query: 132 KKKAEREEYRKSWSTATSPLGGERPFRSTSMFDMRCEEEAAVQPHSRARQEQLQLINNQL 191
+++ +R+E + W E +R + E+ + ++E+++ ++
Sbjct: 467 REEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKI 526
Query: 192 REEDDK-W-QDDLAR-----WKSRRRSVSQDLIKKEEERKKME-KLLAGEDGTSERRKSI 243
RE+++K W Q++ R W+ + Q+ I +EE+R++ E K+ E+ E+ + +
Sbjct: 527 REQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKV 586
Query: 244 KTYREIVQEKERRERELHE-AYKNARSQEEAEGILQQYIERFTISEAVLERLE 295
E ++E+E + +E E +K E E +Q+ E+ E + E
Sbjct: 587 WRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQE 639
Score = 40.4 bits (93), Expect = 0.007
Identities = 35/155 (22%), Positives = 71/155 (45%), Gaps = 16/155 (10%)
Query: 132 KKKAEREEYRKSWSTATSPLGGERPFRSTSMFDMRCEEEAAVQPHSRARQEQ-LQLINNQ 190
+K+ E+E+ K W E R R EE+ Q R QE+ + +
Sbjct: 563 EKRQEQED--KMWRQ-------EEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEK 613
Query: 191 LREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKM----EKLLAGEDGTSERRKSIKTY 246
+RE+++K Q+ + + + + + +E+ +KM EK+ E+ E+ +++
Sbjct: 614 IREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQ 673
Query: 247 REIVQEKERRERELHEAYKNARS--QEEAEGILQQ 279
E ++E+E++ RE E + QE+ E + +Q
Sbjct: 674 EEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQ 708
Score = 40.0 bits (92), Expect = 0.010
Identities = 40/160 (25%), Positives = 76/160 (47%), Gaps = 29/160 (18%)
Query: 519 KNDVSEEKDQKKPENEMSGKVELVLSQK------VVKPKSPEPEATLTFPFLDKMPEANQ 572
+N +++E + K+ ++ K++LV S+K V + K A L P EA+
Sbjct: 211 RNTITDE-ELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEAD- 268
Query: 573 LHLPNLNSQVDSPSSEKSPVMTPFKFWA---WDPEEERRRQEKWQQEQERLLQERYQK-- 627
+L ++ S S++ + + W EE+ RQE+ QE E +QE+ +K
Sbjct: 269 ----HLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIR 324
Query: 628 -EQDKLKEE-----------WEKAQKEVEEEERRYYEEER 655
+++K++E+ WEK +K +EE + +EE+
Sbjct: 325 EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 364
Score = 40.0 bits (92), Expect = 0.010
Identities = 19/58 (32%), Positives = 36/58 (62%), Gaps = 3/58 (5%)
Query: 601 WDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEE---WEKAQKEVEEEERRYYEEER 655
W EE+ QEK ++E++R QE ++++K+ E+ W + +K E+EE+ +EE+
Sbjct: 454 WRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEK 511
Score = 40.0 bits (92), Expect = 0.010
Identities = 22/60 (36%), Positives = 40/60 (66%), Gaps = 4/60 (6%)
Query: 604 EEERRRQEK-WQQEQERLLQERYQKEQDKLKEEWEKAQKEVEE---EERRYYEEERKIIE 659
EE+R+ QE+ W+QE++ QE ++++K+ E+ EK +K+ E+ +E + E+E KI E
Sbjct: 469 EEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIRE 528
Score = 38.9 bits (89), Expect = 0.021
Identities = 26/118 (22%), Positives = 54/118 (45%), Gaps = 13/118 (11%)
Query: 168 EEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEER---- 223
EE+ Q RQE+ ++ E++K + W+ +R +D + ++EE+
Sbjct: 523 EEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQ 582
Query: 224 -----KKMEKLLAGEDGTSERRKSIKTYREIVQEKERR----ERELHEAYKNARSQEE 272
++ EK+ E+ E+ + + E ++E+E + E ++ E + R QEE
Sbjct: 583 EEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEE 640
Score = 38.5 bits (88), Expect = 0.028
Identities = 37/156 (23%), Positives = 77/156 (49%), Gaps = 16/156 (10%)
Query: 168 EEEAAVQPHSRARQEQLQLINNQLREEDDK-WQDD--LARWKSRRRSVSQDLIKKEEE-R 223
+E +V +A+ E+ +L N +++++K W+ + + W+ + + + + ++EE+ R
Sbjct: 272 KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIR 331
Query: 224 KKMEKLLAGEDGTSERRKSIKTYREIVQEKE----RRERELHEAYKNARSQEEAEGILQQ 279
++ EK+ E+ E+ + ++ E++ EKE R+E + E + R QEE ++
Sbjct: 332 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 391
Query: 280 YI--------ERFTISEAVLERLEMPKILERSHSTE 307
I E+ I E +R E KI E+ E
Sbjct: 392 KIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQE 427
Score = 38.5 bits (88), Expect = 0.028
Identities = 32/160 (20%), Positives = 75/160 (46%), Gaps = 19/160 (11%)
Query: 165 MRCEEEAAVQPHSRARQEQLQLINNQ---LREEDDKWQDDLARWKSRRRSVSQDLIKKEE 221
MR +EE + + R+++ + + R+E+ W+ + + + Q+ I+++E
Sbjct: 351 MRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQE 410
Query: 222 ERKKMEKLLAGEDGTSERRKSIKTYREIVQEKE-----------RRERELHEAYKNARSQ 270
E+++ E+ + ++ E+ + E ++E+E R+E ++HE K R +
Sbjct: 411 EKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEK-IREE 469
Query: 271 EEAEGILQQYIERFTISEAVLERLEMPKILERSHSTEPNL 310
E+ Q+ E + E + E+ E+ + E+ H E +
Sbjct: 470 EKR----QEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKI 505
Score = 38.5 bits (88), Expect = 0.028
Identities = 18/62 (29%), Positives = 39/62 (62%), Gaps = 3/62 (4%)
Query: 601 WDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEK---AQKEVEEEERRYYEEERKI 657
W EE+ R QE+ +E+E++ ++ E++K +E+ +K ++++ E+E + + +E KI
Sbjct: 534 WRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKI 593
Query: 658 IE 659
E
Sbjct: 594 RE 595
Score = 38.5 bits (88), Expect = 0.028
Identities = 20/64 (31%), Positives = 41/64 (64%), Gaps = 6/64 (9%)
Query: 602 DPEEERRRQEKWQQEQERLL---QERYQKEQDKLKEEWEKAQKEVE---EEERRYYEEER 655
+ EE+ QE+ QEQE + +E+ ++++ K++E+ EK +++ E E+E + +E+E
Sbjct: 651 EQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEE 710
Query: 656 KIIE 659
K+ E
Sbjct: 711 KMCE 714
Score = 38.5 bits (88), Expect = 0.028
Identities = 22/64 (34%), Positives = 41/64 (64%), Gaps = 6/64 (9%)
Query: 602 DPEEERRRQEKWQQEQERLLQERYQK---EQDKLKEEWEKAQKEVE---EEERRYYEEER 655
+ EE+ R QE+ QEQE + E+ +K +++K++E+ EK +++ E E+E R ++E
Sbjct: 686 EQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEE 745
Query: 656 KIIE 659
K+ E
Sbjct: 746 KMQE 749
Score = 38.1 bits (87), Expect = 0.037
Identities = 30/142 (21%), Positives = 71/142 (50%), Gaps = 8/142 (5%)
Query: 524 EEKDQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQL--HLPNLNSQ 581
+E+ ++ E +M + E + Q+ ++ + E + +K+ E ++ ++ Q
Sbjct: 442 QEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQ 501
Query: 582 VDSPSSEKSPVMTPFKFWAWDPEEERRRQEK-WQQEQERLLQERYQKEQDKLKEE---WE 637
+ ++ V + E+ R ++EK W+QE++ QE +E++K+ E+ WE
Sbjct: 502 EEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWE 561
Query: 638 KAQKEVEEEERRYYEEERKIIE 659
+ ++ +E+E + + +E KI E
Sbjct: 562 EEKR--QEQEDKMWRQEEKIRE 581
Score = 37.7 bits (86), Expect = 0.048
Identities = 22/65 (33%), Positives = 41/65 (63%), Gaps = 9/65 (13%)
Query: 602 DPEEERRRQEK--WQQ-----EQERLLQERYQKEQDKLKEEWEK--AQKEVEEEERRYYE 652
+ EE+ R QEK W+Q EQE++ +E ++EQ+++ + EK Q+E+ ++ + +E
Sbjct: 441 EQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHE 500
Query: 653 EERKI 657
+E KI
Sbjct: 501 QEEKI 505
Score = 37.4 bits (85), Expect = 0.062
Identities = 21/61 (34%), Positives = 38/61 (62%), Gaps = 7/61 (11%)
Query: 602 DPEEERRRQEK--WQQEQERLLQER--YQKEQDKLKEE---WEKAQKEVEEEERRYYEEE 654
+ EE+ RRQE+ W++E++ QE ++KE+ ++E WEK +K +EE + +EE
Sbjct: 332 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 391
Query: 655 R 655
+
Sbjct: 392 K 392
Score = 37.4 bits (85), Expect = 0.062
Identities = 33/158 (20%), Positives = 71/158 (44%), Gaps = 11/158 (6%)
Query: 131 RKKKAEREEYRKSWSTATSPLGGERPFRSTSMFDMRCEEEAAVQPHSRARQEQLQLINNQ 190
R+++ RE+ K W E+ + + ++E ++ QEQ + I Q
Sbjct: 574 RQEEKIREQEEKVWRQEEKIR--EQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQ 631
Query: 191 ---LREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKM----EKLLAGEDGTSERRKSI 243
+RE+++ Q+ + + + + K +E+ + M EK+ E E+ + I
Sbjct: 632 EEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKI 691
Query: 244 KTYREIVQEKERR--ERELHEAYKNARSQEEAEGILQQ 279
+ E++QE+E + E+E + + QE+ E + +Q
Sbjct: 692 REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQ 729
Score = 37.0 bits (84), Expect = 0.082
Identities = 17/54 (31%), Positives = 33/54 (61%)
Query: 602 DPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEER 655
+ EE+ R QE+ + QE ++ E+ +K + + + WEK +K +EE + +EE+
Sbjct: 325 EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 378
Score = 37.0 bits (84), Expect = 0.082
Identities = 18/58 (31%), Positives = 37/58 (63%), Gaps = 5/58 (8%)
Query: 604 EEERRRQEKWQQEQERLLQERYQKEQDKLKEE----WEKAQKEVEEEERRYYEEERKI 657
EE+ QEK ++++E+ +E +EQ+K +E+ W + +K + E+E + E+E+K+
Sbjct: 397 EEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEK-IREQEEKIREQEKKM 453
Score = 37.0 bits (84), Expect = 0.082
Identities = 18/61 (29%), Positives = 40/61 (65%), Gaps = 3/61 (4%)
Query: 602 DPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEK---AQKEVEEEERRYYEEERKII 658
+ E+ R ++EK Q+E++ QE+ Q+++ K+ + EK ++++ E+E++ + +E KI
Sbjct: 402 EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIH 461
Query: 659 E 659
E
Sbjct: 462 E 462
Score = 37.0 bits (84), Expect = 0.082
Identities = 20/57 (35%), Positives = 38/57 (66%), Gaps = 3/57 (5%)
Query: 601 WDPEEERRRQEKWQQEQERLLQERYQK--EQDKLKEEWEK-AQKEVEEEERRYYEEE 654
W EE+ R QE+ +EQE+ + + +K EQ+K++EE ++ Q+E+ +E + +E+E
Sbjct: 433 WRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQE 489
Score = 35.8 bits (81), Expect = 0.18
Identities = 19/63 (30%), Positives = 41/63 (65%), Gaps = 12/63 (19%)
Query: 604 EEERRRQEKWQQEQERLL---QERYQKEQDKLKEE----WEKAQK-----EVEEEERRYY 651
EEE+ R+++ +QEQE + +E+ +++++K++E+ W + +K ++ EEE+R
Sbjct: 415 EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQE 474
Query: 652 EEE 654
+EE
Sbjct: 475 QEE 477
Score = 32.3 bits (72), Expect = 2.0
Identities = 23/109 (21%), Positives = 54/109 (49%), Gaps = 6/109 (5%)
Query: 168 EEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLI--KKEEERKK 225
EE+ Q RQE++ +EE + Q+++ K + ++++ K+E+ R++
Sbjct: 327 EEKIREQEEKMRRQEEMMWE----KEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQ 382
Query: 226 MEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAE 274
E + E+ E + + +I +++E+R+ E + R ++EA+
Sbjct: 383 EEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 431
Score = 32.3 bits (72), Expect = 2.0
Identities = 17/61 (27%), Positives = 37/61 (60%), Gaps = 3/61 (4%)
Query: 602 DPEEERRRQEKWQQEQERLLQERYQK---EQDKLKEEWEKAQKEVEEEERRYYEEERKII 658
+ E + RQE+ +EQE ++E+ +K +++K+ E+ + ++E +E+ + +E KI
Sbjct: 427 EQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIH 486
Query: 659 E 659
E
Sbjct: 487 E 487
Score = 31.2 bits (69), Expect = 4.5
Identities = 22/101 (21%), Positives = 50/101 (49%), Gaps = 17/101 (16%)
Query: 167 CEEEAAVQPHSRARQEQLQLINNQ---LREEDDKWQDDLARWKSRRRSVSQDLIKKEEER 223
CE+E +Q Q + I Q +RE+++K ++ +++++++EE+
Sbjct: 657 CEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQ------------EEMMQEQEEK 704
Query: 224 --KKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHE 262
++ EK+ E+ E+ + ++ E + E+E R R+ E
Sbjct: 705 MWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEE 745
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 47.8 bits (112), Expect = 5e-05
Identities = 43/173 (24%), Positives = 76/173 (43%), Gaps = 11/173 (6%)
Query: 137 REEYRKSWSTATSPLGGERPFRSTSMFDMRCEEEAAVQPHS-RARQEQLQLINNQLREED 195
RE+ K W E R R EE+ Q R ++E++ ++RE+D
Sbjct: 321 REQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQD 380
Query: 196 DKWQD-DLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKE 254
+K Q+ + W+ + +E+E K+ EK+ E E+ + I+ E + +E
Sbjct: 381 EKIQEQEEEMWRQEEKI-------REQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQE 433
Query: 255 RRERELHEAYKNARSQ-EEAEGILQQYIERFTISEAVLERLEMPKILERSHST 306
+ REL E ++ + E E +Q+ E+ E ++R E KI E+ T
Sbjct: 434 EKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQE-EKIQEQEEKT 485
Score = 45.4 bits (106), Expect = 2e-04
Identities = 56/244 (22%), Positives = 105/244 (43%), Gaps = 37/244 (15%)
Query: 513 PSSPQLKNDVSEEKDQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQ 572
PS +N +++E + K+ E+ K+ LV S+K E L L + E Q
Sbjct: 202 PSLELYRNTITDE-ELKEKNAELQEKLRLVESEK--------SEIQLNVKDLKRKLERAQ 252
Query: 573 LHLPNLNSQVDSPSSEKSPVMTPFKFWA-------WD-----PEEERRRQEKWQQEQE-- 618
L LP QV++ K K A W+ EE+ RQE+ QEQE
Sbjct: 253 LLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEK 312
Query: 619 --------RLLQERYQKEQDKLKEEWEKAQKEVEE---EERRYYEEERKIIEDTVVPFTV 667
R +E+ ++++K+ E+ EK +++ ++ +E + E+E KI E +
Sbjct: 313 MCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQ 372
Query: 668 SSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESD--R 725
+Q E + + ++++Q++ W++ + + D ++ +E + R
Sbjct: 373 EEKIREQDEKIQEQEEEMWRQEE-KIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWR 431
Query: 726 LEEK 729
EEK
Sbjct: 432 QEEK 435
Score = 42.0 bits (97), Expect = 0.003
Identities = 37/168 (22%), Positives = 78/168 (46%), Gaps = 8/168 (4%)
Query: 130 LRKKKAEREEYRKSWSTATSPLGGERPFRSTSMFDMRCEEEAA-VQPHSRARQEQLQLIN 188
+R+++ +R+E K W + R R EE+ ++ + ++E+L+ +
Sbjct: 397 IREQEEKRQE--KMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVE 454
Query: 189 NQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYRE 248
+++EE++K Q+ + + + + + +EE+ + EKLL E+ E+ + + E
Sbjct: 455 EKMQEEEEKMQEQEEKIQRQEEKIQE----QEEKTWRQEKLLKQEEKIWEQEEKMWRQEE 510
Query: 249 IVQEKERRERELHE-AYKNARSQEEAEGILQQYIERFTISEAVLERLE 295
+ E+E + +E E + E E L Q E+ E L+ LE
Sbjct: 511 KMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELE 558
Score = 40.8 bits (94), Expect = 0.006
Identities = 34/148 (22%), Positives = 69/148 (46%), Gaps = 19/148 (12%)
Query: 602 DPEEERRRQEKWQQEQERLLQE---RYQKEQDKLKEEWEKA--QKEVEEEERRYYEEERK 656
D EE+ R E+ QE+E +QE + Q++++K++E+ EK Q+++ ++E + +E+E K
Sbjct: 445 DQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEK 504
Query: 657 IIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDL 716
+ + +Q E E++ R W++ + + ++
Sbjct: 505 MWRQEEKMWEQEEKMQEQEEKMQRQEEK------------MREQEVRLWQQEEKMQEQEV 552
Query: 717 LLKTRES--DRLEEKGSLTEGALAHSGN 742
L+ E +L +K L GA SG+
Sbjct: 553 RLQELEERLGKLGQKAELLGGAGRESGS 580
Score = 40.0 bits (92), Expect = 0.010
Identities = 29/139 (20%), Positives = 61/139 (43%), Gaps = 5/139 (3%)
Query: 522 VSEEKDQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQ 581
+ E++++ + E ++E ++ + K + E + + + E Q + Q
Sbjct: 422 IREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQ 481
Query: 582 VDSPSSEKSPVMTPFKFWA-----WDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEW 636
+ ++ + K W W EE+ QE+ QEQE +Q + +K +++ W
Sbjct: 482 EEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLW 541
Query: 637 EKAQKEVEEEERRYYEEER 655
++ +K E+E R EER
Sbjct: 542 QQEEKMQEQEVRLQELEER 560
Score = 38.9 bits (89), Expect = 0.021
Identities = 21/58 (36%), Positives = 35/58 (60%), Gaps = 4/58 (6%)
Query: 602 DPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIE 659
+ EEE RQE+ +EQE QE+ +++ K++E+ EK + E+E + +E KI E
Sbjct: 385 EQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEK----IREQEEEMWRQEEKIRE 438
Score = 38.1 bits (87), Expect = 0.037
Identities = 21/55 (38%), Positives = 35/55 (63%), Gaps = 4/55 (7%)
Query: 602 DPEEERRRQEKWQQEQE-RLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEER 655
D + + +E W+QE++ R L+E Q +++KL+E EK Q EEEE+ +EE+
Sbjct: 419 DEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQ---EEEEKMQEQEEK 470
Score = 37.4 bits (85), Expect = 0.062
Identities = 27/97 (27%), Positives = 46/97 (47%), Gaps = 10/97 (10%)
Query: 166 RCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKK 225
R EE+ Q RQE+L L++E+ W+ + W+ + Q+ +E+E
Sbjct: 473 RQEEKIQEQEEKTWRQEKL------LKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQE--- 523
Query: 226 MEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHE 262
EK+ E+ E+ + E +QE+E R +EL E
Sbjct: 524 -EKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEE 559
Score = 37.0 bits (84), Expect = 0.082
Identities = 23/81 (28%), Positives = 42/81 (51%), Gaps = 25/81 (30%)
Query: 604 EEERRRQEKWQQEQE----------------------RLLQERYQKEQDKLKEEWEKAQK 641
+EE+R+++ W+QE++ R L+E Q +++KL+E EK Q+
Sbjct: 400 QEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQE 459
Query: 642 E---VEEEERRYYEEERKIIE 659
E ++E+E + +E KI E
Sbjct: 460 EEEKMQEQEEKIQRQEEKIQE 480
Score = 36.2 bits (82), Expect = 0.14
Identities = 20/59 (33%), Positives = 36/59 (61%), Gaps = 4/59 (6%)
Query: 601 WDPEEERRRQEKWQQE----QERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEER 655
W EE+ R QE+ +QE QE+ ++E+ +K +++ +E W + +K E EE +EE+
Sbjct: 391 WRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEK 449
Score = 35.8 bits (81), Expect = 0.18
Identities = 21/63 (33%), Positives = 37/63 (58%), Gaps = 6/63 (9%)
Query: 601 WDPEEERRRQEKW--QQEQERLLQERYQKEQDKLKEEWEKAQKEVE----EEERRYYEEE 654
W E++ R Q++ +QE+E QE +E +++ ++ E+ +EVE EEE + E+E
Sbjct: 409 WRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQE 468
Query: 655 RKI 657
KI
Sbjct: 469 EKI 471
Score = 35.4 bits (80), Expect = 0.24
Identities = 33/135 (24%), Positives = 66/135 (48%), Gaps = 8/135 (5%)
Query: 168 EEEAAVQPHSRARQEQLQLIN--NQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERK- 224
+E +V +A+ E+ +L N NQ ++E+ W+ + + + Q+L +E+E K
Sbjct: 269 KELQSVSAKLQAQVEENELWNLLNQ-QQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKM 327
Query: 225 --KMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAY--KNARSQEEAEGILQQY 280
+ EK+ E+ E+ + E ++E+E + RE E + + +E+ E I +Q
Sbjct: 328 WRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQE 387
Query: 281 IERFTISEAVLERLE 295
E + E + E+ E
Sbjct: 388 EEMWRQEEKIREQEE 402
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 47.8 bits (112), Expect = 5e-05
Identities = 43/173 (24%), Positives = 76/173 (43%), Gaps = 11/173 (6%)
Query: 137 REEYRKSWSTATSPLGGERPFRSTSMFDMRCEEEAAVQPHS-RARQEQLQLINNQLREED 195
RE+ K W E R R EE+ Q R ++E++ ++RE+D
Sbjct: 321 REQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQD 380
Query: 196 DKWQD-DLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKE 254
+K Q+ + W+ + +E+E K+ EK+ E E+ + I+ E + +E
Sbjct: 381 EKIQEQEEEMWRQEEKI-------REQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQE 433
Query: 255 RRERELHEAYKNARSQ-EEAEGILQQYIERFTISEAVLERLEMPKILERSHST 306
+ REL E ++ + E E +Q+ E+ E ++R E KI E+ T
Sbjct: 434 EKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQE-EKIQEQEEKT 485
Score = 43.5 bits (101), Expect = 9e-04
Identities = 54/238 (22%), Positives = 103/238 (43%), Gaps = 37/238 (15%)
Query: 519 KNDVSEEKDQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNL 578
+N +++E + K+ E+ K+ LV S+K E L L + E QL LP
Sbjct: 208 RNTITDE-ELKEKNAELQEKLRLVESEK--------SEIQLNVKDLKRKLERAQLLLPQQ 258
Query: 579 NSQVDSPSSEKSPVMTPFKFWA-------WD-----PEEERRRQEKWQQEQE-------- 618
QV++ K K A W+ EE+ RQE+ QEQE
Sbjct: 259 QLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQEL 318
Query: 619 --RLLQERYQKEQDKLKEEWEKAQKEVEE---EERRYYEEERKIIEDTVVPFTVSSSSAD 673
R +E+ ++++K+ E+ EK +++ ++ +E + E+E KI E + +
Sbjct: 319 KIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIRE 378
Query: 674 QLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESD--RLEEK 729
Q E + + ++++Q++ W++ + + D ++ +E + R EEK
Sbjct: 379 QDEKIQEQEEEMWRQEE-KIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEK 435
Score = 42.0 bits (97), Expect = 0.003
Identities = 37/168 (22%), Positives = 78/168 (46%), Gaps = 8/168 (4%)
Query: 130 LRKKKAEREEYRKSWSTATSPLGGERPFRSTSMFDMRCEEEAA-VQPHSRARQEQLQLIN 188
+R+++ +R+E K W + R R EE+ ++ + ++E+L+ +
Sbjct: 397 IREQEEKRQE--KMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVE 454
Query: 189 NQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYRE 248
+++EE++K Q+ + + + + + +EE+ + EKLL E+ E+ + + E
Sbjct: 455 EKMQEEEEKMQEQEEKIQRQEEKIQE----QEEKTWRQEKLLKQEEKIWEQEEKMWRQEE 510
Query: 249 IVQEKERRERELHE-AYKNARSQEEAEGILQQYIERFTISEAVLERLE 295
+ E+E + +E E + E E L Q E+ E L+ LE
Sbjct: 511 KMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELE 558
Score = 40.8 bits (94), Expect = 0.006
Identities = 34/148 (22%), Positives = 69/148 (46%), Gaps = 19/148 (12%)
Query: 602 DPEEERRRQEKWQQEQERLLQE---RYQKEQDKLKEEWEKA--QKEVEEEERRYYEEERK 656
D EE+ R E+ QE+E +QE + Q++++K++E+ EK Q+++ ++E + +E+E K
Sbjct: 445 DQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEK 504
Query: 657 IIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDL 716
+ + +Q E E++ R W++ + + ++
Sbjct: 505 MWRQEEKMWEQEEKMQEQEEKMQRQEEK------------MREQEVRLWQQEEKMQEQEV 552
Query: 717 LLKTRES--DRLEEKGSLTEGALAHSGN 742
L+ E +L +K L GA SG+
Sbjct: 553 RLQELEERLGKLGQKAELLGGAGRESGS 580
Score = 40.0 bits (92), Expect = 0.010
Identities = 29/139 (20%), Positives = 61/139 (43%), Gaps = 5/139 (3%)
Query: 522 VSEEKDQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQ 581
+ E++++ + E ++E ++ + K + E + + + E Q + Q
Sbjct: 422 IREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQ 481
Query: 582 VDSPSSEKSPVMTPFKFWA-----WDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEW 636
+ ++ + K W W EE+ QE+ QEQE +Q + +K +++ W
Sbjct: 482 EEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLW 541
Query: 637 EKAQKEVEEEERRYYEEER 655
++ +K E+E R EER
Sbjct: 542 QQEEKMQEQEVRLQELEER 560
Score = 38.9 bits (89), Expect = 0.021
Identities = 21/58 (36%), Positives = 35/58 (60%), Gaps = 4/58 (6%)
Query: 602 DPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIE 659
+ EEE RQE+ +EQE QE+ +++ K++E+ EK + E+E + +E KI E
Sbjct: 385 EQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEK----IREQEEEMWRQEEKIRE 438
Score = 38.1 bits (87), Expect = 0.037
Identities = 21/55 (38%), Positives = 35/55 (63%), Gaps = 4/55 (7%)
Query: 602 DPEEERRRQEKWQQEQE-RLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEER 655
D + + +E W+QE++ R L+E Q +++KL+E EK Q EEEE+ +EE+
Sbjct: 419 DEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQ---EEEEKMQEQEEK 470
Score = 37.4 bits (85), Expect = 0.062
Identities = 27/97 (27%), Positives = 46/97 (47%), Gaps = 10/97 (10%)
Query: 166 RCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKK 225
R EE+ Q RQE+L L++E+ W+ + W+ + Q+ +E+E
Sbjct: 473 RQEEKIQEQEEKTWRQEKL------LKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQE--- 523
Query: 226 MEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHE 262
EK+ E+ E+ + E +QE+E R +EL E
Sbjct: 524 -EKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEE 559
Score = 37.0 bits (84), Expect = 0.082
Identities = 23/81 (28%), Positives = 42/81 (51%), Gaps = 25/81 (30%)
Query: 604 EEERRRQEKWQQEQE----------------------RLLQERYQKEQDKLKEEWEKAQK 641
+EE+R+++ W+QE++ R L+E Q +++KL+E EK Q+
Sbjct: 400 QEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQE 459
Query: 642 E---VEEEERRYYEEERKIIE 659
E ++E+E + +E KI E
Sbjct: 460 EEEKMQEQEEKIQRQEEKIQE 480
Score = 36.2 bits (82), Expect = 0.14
Identities = 20/59 (33%), Positives = 36/59 (61%), Gaps = 4/59 (6%)
Query: 601 WDPEEERRRQEKWQQE----QERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEER 655
W EE+ R QE+ +QE QE+ ++E+ +K +++ +E W + +K E EE +EE+
Sbjct: 391 WRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEK 449
Score = 35.8 bits (81), Expect = 0.18
Identities = 21/63 (33%), Positives = 37/63 (58%), Gaps = 6/63 (9%)
Query: 601 WDPEEERRRQEKW--QQEQERLLQERYQKEQDKLKEEWEKAQKEVE----EEERRYYEEE 654
W E++ R Q++ +QE+E QE +E +++ ++ E+ +EVE EEE + E+E
Sbjct: 409 WRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQE 468
Query: 655 RKI 657
KI
Sbjct: 469 EKI 471
Score = 35.4 bits (80), Expect = 0.24
Identities = 33/135 (24%), Positives = 66/135 (48%), Gaps = 8/135 (5%)
Query: 168 EEEAAVQPHSRARQEQLQLIN--NQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERK- 224
+E +V +A+ E+ +L N NQ ++E+ W+ + + + Q+L +E+E K
Sbjct: 269 KELQSVSAKLQAQVEENELWNLLNQ-QQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKM 327
Query: 225 --KMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAY--KNARSQEEAEGILQQY 280
+ EK+ E+ E+ + E ++E+E + RE E + + +E+ E I +Q
Sbjct: 328 WRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQE 387
Query: 281 IERFTISEAVLERLE 295
E + E + E+ E
Sbjct: 388 EEMWRQEEKIREQEE 402
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.126 0.357
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,298,925
Number of Sequences: 37866
Number of extensions: 2056672
Number of successful extensions: 25251
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 343
Number of HSP's successfully gapped in prelim test: 837
Number of HSP's that attempted gapping in prelim test: 11719
Number of HSP's gapped (non-prelim): 8104
length of query: 890
length of database: 18,247,518
effective HSP length: 111
effective length of query: 779
effective length of database: 14,044,392
effective search space: 10940581368
effective search space used: 10940581368
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.