Search of human proteins with 158341646

Search of human proteins with 158341646

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|158341646 hypothetical protein LOC729830 [Homo sapiens]
         (1040 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|158341646 hypothetical protein LOC729830 [Homo sapiens]           2083   0.0  
gi|149393138 hypothetical protein LOC84067 isoform 2 [Homo sapiens]   507   e-143
gi|149393140 hypothetical protein LOC84067 isoform 1 [Homo sapiens]   482   e-136
gi|89337270 retinoic acid induced 16 [Homo sapiens]                    72   4e-12
gi|205277429 hypothetical protein LOC57700 isoform b [Homo sapiens]    63   2e-09
gi|205277427 hypothetical protein LOC57700 isoform a [Homo sapiens]    63   2e-09
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ...    47   9e-05
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ...    47   9e-05
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)...    46   2e-04
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)...    46   2e-04
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)...    46   2e-04
gi|40807447 papillary renal cell carcinoma translocation-associa...    46   2e-04
gi|125656165 THO complex 2 [Homo sapiens]                              45   4e-04
gi|7019419 guanine nucleotide binding protein-like 2 (nucleolar)...    44   8e-04
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    44   0.001
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]                       44   0.001
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]              43   0.001
gi|7657138 golgi integral membrane protein 4 [Homo sapiens]            43   0.002
gi|33188449 serine/arginine-rich protein-specific kinase 2 isofo...    42   0.002
gi|33188447 serine/arginine-rich protein-specific kinase 2 isofo...    42   0.002
gi|54112403 chromodomain helicase DNA binding protein 7 [Homo sa...    42   0.003
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)...    42   0.003
gi|23503317 coiled-coil domain containing 96 [Homo sapiens]            42   0.003
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     42   0.004
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom...    42   0.004
gi|158631177 homeodomain leucine zipper protein [Homo sapiens]         41   0.005
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]         40   0.009
gi|157738619 smoothelin-like 1 [Homo sapiens]                          40   0.009
gi|21735415 centromere protein B [Homo sapiens]                        40   0.011
gi|48255877 troponin T type 2, cardiac isoform 1 [Homo sapiens]        40   0.011

>gi|158341646 hypothetical protein LOC729830 [Homo sapiens]
          Length = 1040

 Score = 2083 bits (5396), Expect = 0.0
 Identities = 1040/1040 (100%), Positives = 1040/1040 (100%)

Query: 1    MMSSVSTESKLQQAVSLQGVDPETCMIVFKNHWAQVVKILEKHDPLKNTQAKYGSIPPDE 60
            MMSSVSTESKLQQAVSLQGVDPETCMIVFKNHWAQVVKILEKHDPLKNTQAKYGSIPPDE
Sbjct: 1    MMSSVSTESKLQQAVSLQGVDPETCMIVFKNHWAQVVKILEKHDPLKNTQAKYGSIPPDE 60

Query: 61   ASAVQNYVEHMLFLLIEEQAKDAAMGPILEFVVSENIMEKLFLWSLRREFTDETKIEQLK 120
            ASAVQNYVEHMLFLLIEEQAKDAAMGPILEFVVSENIMEKLFLWSLRREFTDETKIEQLK
Sbjct: 61   ASAVQNYVEHMLFLLIEEQAKDAAMGPILEFVVSENIMEKLFLWSLRREFTDETKIEQLK 120

Query: 121  MYEMLVTQSHQPLLHHKPILKPLMMLLSSCSGTTTPTVEEKLVVLLNQLCSILAKDPSIL 180
            MYEMLVTQSHQPLLHHKPILKPLMMLLSSCSGTTTPTVEEKLVVLLNQLCSILAKDPSIL
Sbjct: 121  MYEMLVTQSHQPLLHHKPILKPLMMLLSSCSGTTTPTVEEKLVVLLNQLCSILAKDPSIL 180

Query: 181  ELFFHTSEDQGAANFLIFSLLIPFIHREGSVGQQARDALLFIMSLSAENTMVAHHIVENT 240
            ELFFHTSEDQGAANFLIFSLLIPFIHREGSVGQQARDALLFIMSLSAENTMVAHHIVENT
Sbjct: 181  ELFFHTSEDQGAANFLIFSLLIPFIHREGSVGQQARDALLFIMSLSAENTMVAHHIVENT 240

Query: 241  YFCPVLATGLSGLYSSLPTKLEEKGEEWHCLLKDDWLLLPSLVQFMNSLEFCNAVIQVAH 300
            YFCPVLATGLSGLYSSLPTKLEEKGEEWHCLLKDDWLLLPSLVQFMNSLEFCNAVIQVAH
Sbjct: 241  YFCPVLATGLSGLYSSLPTKLEEKGEEWHCLLKDDWLLLPSLVQFMNSLEFCNAVIQVAH 300

Query: 301  PLIRNQLVNYIYNGFLVPVLAPALHKVTVEEVMTTTAYLDLFLRSISEPALLEIFLRFIL 360
            PLIRNQLVNYIYNGFLVPVLAPALHKVTVEEVMTTTAYLDLFLRSISEPALLEIFLRFIL
Sbjct: 301  PLIRNQLVNYIYNGFLVPVLAPALHKVTVEEVMTTTAYLDLFLRSISEPALLEIFLRFIL 360

Query: 361  LHQHENVHILDTLTSRINTPFRLCVVSLALFRTLIGLHCEDVMLQLVLRYLIPCNHMMLS 420
            LHQHENVHILDTLTSRINTPFRLCVVSLALFRTLIGLHCEDVMLQLVLRYLIPCNHMMLS
Sbjct: 361  LHQHENVHILDTLTSRINTPFRLCVVSLALFRTLIGLHCEDVMLQLVLRYLIPCNHMMLS 420

Query: 421  QRWAVKERDCYSVSAAKLLALTPVCCSSGITLTLGNQERDYILWSKCMHDTSGPVERPFP 480
            QRWAVKERDCYSVSAAKLLALTPVCCSSGITLTLGNQERDYILWSKCMHDTSGPVERPFP
Sbjct: 421  QRWAVKERDCYSVSAAKLLALTPVCCSSGITLTLGNQERDYILWSKCMHDTSGPVERPFP 480

Query: 481  EAFSESACIVEYGKALDISYLQYLWEAHTNILRCMRDCRVWSALYDGDSPDPEMFLQSLT 540
            EAFSESACIVEYGKALDISYLQYLWEAHTNILRCMRDCRVWSALYDGDSPDPEMFLQSLT
Sbjct: 481  EAFSESACIVEYGKALDISYLQYLWEAHTNILRCMRDCRVWSALYDGDSPDPEMFLQSLT 540

Query: 541  EEGSVSSACPVFGLPQQLPRKTGPQLAPRKDKSQTELEWDDSYDTGISSGADVGSPGPYD 600
            EEGSVSSACPVFGLPQQLPRKTGPQLAPRKDKSQTELEWDDSYDTGISSGADVGSPGPYD
Sbjct: 541  EEGSVSSACPVFGLPQQLPRKTGPQLAPRKDKSQTELEWDDSYDTGISSGADVGSPGPYD 600

Query: 601  DLEVSGPPAPIDPPKHIQEMKKNALLLFKGSYIEESDFQDDVMVYRLCAEKDSEDMKDSQ 660
            DLEVSGPPAPIDPPKHIQEMKKNALLLFKGSYIEESDFQDDVMVYRLCAEKDSEDMKDSQ
Sbjct: 601  DLEVSGPPAPIDPPKHIQEMKKNALLLFKGSYIEESDFQDDVMVYRLCAEKDSEDMKDSQ 660

Query: 661  EEAARPPAEAQAEVQSVPINNGPLLSTQPETDSEEEWNRDNSDPFHSEPKEPKQEREPEA 720
            EEAARPPAEAQAEVQSVPINNGPLLSTQPETDSEEEWNRDNSDPFHSEPKEPKQEREPEA
Sbjct: 661  EEAARPPAEAQAEVQSVPINNGPLLSTQPETDSEEEWNRDNSDPFHSEPKEPKQEREPEA 720

Query: 721  APESNSELASPAPEAEHSSNLTAAHPESEELIAQYDQIIKELDSGAEGLMEQNYPTPDPL 780
            APESNSELASPAPEAEHSSNLTAAHPESEELIAQYDQIIKELDSGAEGLMEQNYPTPDPL
Sbjct: 721  APESNSELASPAPEAEHSSNLTAAHPESEELIAQYDQIIKELDSGAEGLMEQNYPTPDPL 780

Query: 781  LLTKEEEGKEESKGEKEKEGKKELEDEEDDFDSFIAEMPAVETVPSPFVGRDEAAFASRH 840
            LLTKEEEGKEESKGEKEKEGKKELEDEEDDFDSFIAEMPAVETVPSPFVGRDEAAFASRH
Sbjct: 781  LLTKEEEGKEESKGEKEKEGKKELEDEEDDFDSFIAEMPAVETVPSPFVGRDEAAFASRH 840

Query: 841  PVRTQSTPFTGPFISVVLSKLENMLENSLHVNLLLIGIITQLASYPQPLLRSFLLNTNMV 900
            PVRTQSTPFTGPFISVVLSKLENMLENSLHVNLLLIGIITQLASYPQPLLRSFLLNTNMV
Sbjct: 841  PVRTQSTPFTGPFISVVLSKLENMLENSLHVNLLLIGIITQLASYPQPLLRSFLLNTNMV 900

Query: 901  FQPSVRSLYQVLASVKNKIEQFASVERDFPGLLIQAQQYLLFRVDMSDMTPAALTKDPIQ 960
            FQPSVRSLYQVLASVKNKIEQFASVERDFPGLLIQAQQYLLFRVDMSDMTPAALTKDPIQ
Sbjct: 901  FQPSVRSLYQVLASVKNKIEQFASVERDFPGLLIQAQQYLLFRVDMSDMTPAALTKDPIQ 960

Query: 961  EASRTGSGKNLLDGPPRVLQPFLTHRTKVAEAPPNLPLPVRNPMLAAALFPEFLKELAAL 1020
            EASRTGSGKNLLDGPPRVLQPFLTHRTKVAEAPPNLPLPVRNPMLAAALFPEFLKELAAL
Sbjct: 961  EASRTGSGKNLLDGPPRVLQPFLTHRTKVAEAPPNLPLPVRNPMLAAALFPEFLKELAAL 1020

Query: 1021 AQEHSILCYKILGDFEDSCC 1040
            AQEHSILCYKILGDFEDSCC
Sbjct: 1021 AQEHSILCYKILGDFEDSCC 1040


>gi|149393138 hypothetical protein LOC84067 isoform 2 [Homo sapiens]
          Length = 972

 Score =  507 bits (1305), Expect = e-143
 Identities = 277/574 (48%), Positives = 378/574 (65%), Gaps = 57/574 (9%)

Query: 10  KLQQAVSLQG---VDPETCMIVFKNHWAQVVKILEKHDPLKNTQAKYGSIPPDEASAVQN 66
           ++ Q  +LQ     DPETC++VFKNHW+QVV+ILE+  P    +A  G    D+ SAV+N
Sbjct: 18  RIPQGANLQTPVMADPETCLMVFKNHWSQVVRILERQGP----RAAPGGA--DDLSAVRN 71

Query: 67  YVEHMLFLLIEEQAKDAAM---GPILEFVVSENIMEKLFLWSLR----REFTDETKIEQL 119
           +   ML LL E++A  +A    GP+LEF + E+++ ++  W L+     +  +E + EQL
Sbjct: 72  HTYQMLTLLAEDRAVPSAPTGPGPLLEFALHEDLLTRVLTWQLQWDELGDGVEERRAEQL 131

Query: 120 KMYEMLVTQSHQPLLHHKPILKPLMMLLSSCSGT--TTPTVEEKLVVLLNQLCSILAKDP 177
           K++EMLV+++ QPLL H P+ + L+ LL +C     ++P ++E LV+LL+QLC  +A++P
Sbjct: 132 KLFEMLVSEARQPLLRHGPVREALLTLLDACGRPVPSSPALDEGLVLLLSQLCVCVAQEP 191

Query: 178 SILELFFHTSEDQGAA-NFLIFSLLIPFIHREGSVGQQARDALLFIMSLSAENTMVAHHI 236
           S+LE F     + GAA   L+FS L+PF+HREG++GQQARDALL +M+LSA +  V  +I
Sbjct: 192 SLLEFFLQPPPEPGAAPRLLLFSRLVPFVHREGTLGQQARDALLLLMALSAGSPTVGRYI 251

Query: 237 VENTYFCPVLATGLSGLYSSLPTKLEEKGEEWHCLLKDDWLLLPSLVQFMNSLEFCNAVI 296
            +++YFCPVLATGLS LYSSLP K+E  G++WHCL ++DWL +P+L  FM+SLEFCNAVI
Sbjct: 252 ADHSYFCPVLATGLSALYSSLPRKIEVPGDDWHCLRREDWLGVPALALFMSSLEFCNAVI 311

Query: 297 QVAHPLIRNQLVNYIYNGFLVPVLAPALHKVTVEEVMTTTAYLDLFLRSISEPALLEIFL 356
           QVAHPL++ QLV+YI+NGFLVPV+ PALHK +VEE++ +TAYL+LFLRSISEPALL  FL
Sbjct: 312 QVAHPLVQKQLVDYIHNGFLVPVMGPALHKTSVEEMIASTAYLELFLRSISEPALLRTFL 371

Query: 357 RFILLHQHENVHILDTLTSRINTPFRLCVVSLALFRTLIGLHCEDVMLQLVLRYLIPCNH 416
           RF+LLH+H+   ILDTL +RI +  RLC+VSL+LFRTL+ L CEDV+LQLVLRYL+PCNH
Sbjct: 372 RFLLLHRHDTHTILDTLVARIGSNSRLCMVSLSLFRTLLNLSCEDVLLQLVLRYLVPCNH 431

Query: 417 MMLSQRWAVKERDCYSVSAAKLLALTPVCC-------------------------SSGIT 451
           +MLSQ+ AV++ D Y  +A K L+L P CC                         SS +T
Sbjct: 432 VMLSQKPAVRDVDLYGRAADKFLSLIPRCCRHHAPSPPRPEHASWARGPGSPSVDSSSVT 491

Query: 452 LTLGNQERDYILWSKCMHDTSGPVERPFPEAFSESACI------------VEYGKALDIS 499
            T+        L       + G  E P P   S                  E    L+ +
Sbjct: 492 -TVPRPSTPSRLALFLRQQSLGGSESPGPAPCSPGLSASPASSPGRRPTPAEEPGELEDN 550

Query: 500 YLQYLWEAHTNILRCMRDCRVWSALYDGDSPDPE 533
           YL+YL EA   + RC+R CR WSA YDG+ P PE
Sbjct: 551 YLEYLREARRGVDRCVRACRTWSAPYDGERPSPE 584



 Score =  168 bits (425), Expect = 3e-41
 Identities = 108/259 (41%), Positives = 144/259 (55%), Gaps = 52/259 (20%)

Query: 806  DEEDDFDSFIAEMPAVETVPSPFVGRDEAAFASRHPVRT----QSTPFTGPFISVVLSKL 861
            +EE+ ++SF          P PF+           P+RT     S PFTGPF++V+ +KL
Sbjct: 703  EEEEAYESFTCPPEP----PGPFLSS---------PLRTLNQLPSQPFTGPFMAVLFAKL 749

Query: 862  ENMLENSLHVNLLLIGIITQLASYPQPLLRSFLLNTNMVFQPSVRSLYQVLASVKNKIEQ 921
            ENML+NS++VN LL G++ QLA +PQPLLRSFLLNTNMVFQPSV+SL QVL SVKNKIE 
Sbjct: 750  ENMLQNSVYVNFLLTGLVAQLACHPQPLLRSFLLNTNMVFQPSVKSLLQVLGSVKNKIEN 809

Query: 922  FASVERDFPGLLIQAQQYLLFR--VDMSD---MTPAALTKDP------------------ 958
            FA+ + DFP LL +A++YL+ R  +D ++     PA    DP                  
Sbjct: 810  FAASQEDFPALLSKAKKYLIARGKLDWAEGPAAGPAPRRSDPLVKSRRPSLGELLLRHAH 869

Query: 959  -----------IQEASRTGSGKNLLDGPPRVLQPFLTHRTKVAEAPPNLPLPVRNPMLAA 1007
                       + +  R G+G  L  G P    P L  R    E      L V+N +  A
Sbjct: 870  SPTRARQAAQLVLQPGRDGAGLGLSGGSPGASTPVLLTRGGAPERQGE-ALRVKNAVYCA 928

Query: 1008 ALFPEFLKELAALAQEHSI 1026
             +FPEFLKELAA++Q H++
Sbjct: 929  VIFPEFLKELAAISQAHAV 947


>gi|149393140 hypothetical protein LOC84067 isoform 1 [Homo sapiens]
          Length = 986

 Score =  482 bits (1241), Expect = e-136
 Identities = 245/450 (54%), Positives = 337/450 (74%), Gaps = 19/450 (4%)

Query: 10  KLQQAVSLQG---VDPETCMIVFKNHWAQVVKILEKHDPLKNTQAKYGSIPPDEASAVQN 66
           ++ Q  +LQ     DPETC++VFKNHW+QVV+ILE+  P    +A  G    D+ SAV+N
Sbjct: 18  RIPQGANLQTPVMADPETCLMVFKNHWSQVVRILERQGP----RAAPGGA--DDLSAVRN 71

Query: 67  YVEHMLFLLIEEQAKDAAM---GPILEFVVSENIMEKLFLWSLR----REFTDETKIEQL 119
           +   ML LL E++A  +A    GP+LEF + E+++ ++  W L+     +  +E + EQL
Sbjct: 72  HTYQMLTLLAEDRAVPSAPTGPGPLLEFALHEDLLTRVLTWQLQWDELGDGVEERRAEQL 131

Query: 120 KMYEMLVTQSHQPLLHHKPILKPLMMLLSSCSGT--TTPTVEEKLVVLLNQLCSILAKDP 177
           K++EMLV+++ QPLL H P+ + L+ LL +C     ++P ++E LV+LL+QLC  +A++P
Sbjct: 132 KLFEMLVSEARQPLLRHGPVREALLTLLDACGRPVPSSPALDEGLVLLLSQLCVCVAQEP 191

Query: 178 SILELFFHTSEDQGAA-NFLIFSLLIPFIHREGSVGQQARDALLFIMSLSAENTMVAHHI 236
           S+LE F     + GAA   L+FS L+PF+HREG++GQQARDALL +M+LSA +  V  +I
Sbjct: 192 SLLEFFLQPPPEPGAAPRLLLFSRLVPFVHREGTLGQQARDALLLLMALSAGSPTVGRYI 251

Query: 237 VENTYFCPVLATGLSGLYSSLPTKLEEKGEEWHCLLKDDWLLLPSLVQFMNSLEFCNAVI 296
            +++YFCPVLATGLS LYSSLP K+E  G++WHCL ++DWL +P+L  FM+SLEFCNAVI
Sbjct: 252 ADHSYFCPVLATGLSALYSSLPRKIEVPGDDWHCLRREDWLGVPALALFMSSLEFCNAVI 311

Query: 297 QVAHPLIRNQLVNYIYNGFLVPVLAPALHKVTVEEVMTTTAYLDLFLRSISEPALLEIFL 356
           QVAHPL++ QLV+YI+NGFLVPV+ PALHK +VEE++ +TAYL+LFLRSISEPALL  FL
Sbjct: 312 QVAHPLVQKQLVDYIHNGFLVPVMGPALHKTSVEEMIASTAYLELFLRSISEPALLRTFL 371

Query: 357 RFILLHQHENVHILDTLTSRINTPFRLCVVSLALFRTLIGLHCEDVMLQLVLRYLIPCNH 416
           RF+LLH+H+   ILDTL +RI +  RLC+VSL+LFRTL+ L CEDV+LQLVLRYL+PCNH
Sbjct: 372 RFLLLHRHDTHTILDTLVARIGSNSRLCMVSLSLFRTLLNLSCEDVLLQLVLRYLVPCNH 431

Query: 417 MMLSQRWAVKERDCYSVSAAKLLALTPVCC 446
           +MLSQ+ AV++ D Y  +A K L+L P CC
Sbjct: 432 VMLSQKPAVRDVDLYGRAADKFLSLIPRCC 461



 Score =  168 bits (425), Expect = 3e-41
 Identities = 108/259 (41%), Positives = 144/259 (55%), Gaps = 52/259 (20%)

Query: 806  DEEDDFDSFIAEMPAVETVPSPFVGRDEAAFASRHPVRT----QSTPFTGPFISVVLSKL 861
            +EE+ ++SF          P PF+           P+RT     S PFTGPF++V+ +KL
Sbjct: 717  EEEEAYESFTCPPEP----PGPFLSS---------PLRTLNQLPSQPFTGPFMAVLFAKL 763

Query: 862  ENMLENSLHVNLLLIGIITQLASYPQPLLRSFLLNTNMVFQPSVRSLYQVLASVKNKIEQ 921
            ENML+NS++VN LL G++ QLA +PQPLLRSFLLNTNMVFQPSV+SL QVL SVKNKIE 
Sbjct: 764  ENMLQNSVYVNFLLTGLVAQLACHPQPLLRSFLLNTNMVFQPSVKSLLQVLGSVKNKIEN 823

Query: 922  FASVERDFPGLLIQAQQYLLFR--VDMSD---MTPAALTKDP------------------ 958
            FA+ + DFP LL +A++YL+ R  +D ++     PA    DP                  
Sbjct: 824  FAASQEDFPALLSKAKKYLIARGKLDWAEGPAAGPAPRRSDPLVKSRRPSLGELLLRHAH 883

Query: 959  -----------IQEASRTGSGKNLLDGPPRVLQPFLTHRTKVAEAPPNLPLPVRNPMLAA 1007
                       + +  R G+G  L  G P    P L  R    E      L V+N +  A
Sbjct: 884  SPTRARQAAQLVLQPGRDGAGLGLSGGSPGASTPVLLTRGGAPERQGE-ALRVKNAVYCA 942

Query: 1008 ALFPEFLKELAALAQEHSI 1026
             +FPEFLKELAA++Q H++
Sbjct: 943  VIFPEFLKELAAISQAHAV 961



 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 27/62 (43%), Positives = 33/62 (53%), Gaps = 9/62 (14%)

Query: 472 SGPVERPFPEAFSESACIVEYGKALDISYLQYLWEAHTNILRCMRDCRVWSALYDGDSPD 531
           S P  RP P          E    L+ +YL+YL EA   + RC+R CR WSA YDG+ P 
Sbjct: 546 SSPGRRPTP---------AEEPGELEDNYLEYLREARRGVDRCVRACRTWSAPYDGERPS 596

Query: 532 PE 533
           PE
Sbjct: 597 PE 598


>gi|89337270 retinoic acid induced 16 [Homo sapiens]
          Length = 743

 Score = 71.6 bits (174), Expect = 4e-12
 Identities = 65/240 (27%), Positives = 110/240 (45%), Gaps = 32/240 (13%)

Query: 196 LIFSLLIPFIHREGSVGQQARDALLFIMSLSAENTMVAHHIVENTYFCPVLATGLSGLYS 255
           LI SLL     ++  V  +A++ LL ++S+++     A ++V+++  CP +   L  LY 
Sbjct: 245 LITSLLGLCQSKKSRVALKAQENLLLLVSMASP--AAATYLVQSSACCPAIVRHLCQLYR 302

Query: 256 SLPTKLEE------KGEEWHC-LLKDDWLLLP---SLVQFMNSLEFCNAVIQVAHPLIRN 305
           S+P  L+       +G  W       D    P   +L  F+   ++C+ +I  AH ++ +
Sbjct: 303 SMPVFLDPADIATLEGISWRLPSAPSDEASFPGKEALAAFLGWFDYCDHLITEAHTVVAD 362

Query: 306 QLVNYIYNGFLVPVLAPALHKVTVEEVMTTTAYLDLFLRSISEPALLEIFLRFILLHQH- 364
            L   +   F V  L P L  V+ + ++T+TA L   LR +  PALL   + F+L     
Sbjct: 363 ALAKAVAENFFVETLQPQLLHVSEQSILTSTALLTAMLRQLRSPALLREAVAFLLGTDRQ 422

Query: 365 -----ENVHIL--------DTLTSRINTPFRLCVVSLALFRTLIGLHCEDVMLQLVLRYL 411
                +N H L        D L+  I+      + +L LF  L+    E ++  LVLR L
Sbjct: 423 PEAPGDNPHTLYAHLIGHCDHLSDEIS------ITTLRLFEELLQKPHEGIIHSLVLRNL 476



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 49/176 (27%), Positives = 85/176 (48%), Gaps = 20/176 (11%)

Query: 11  LQQAVSLQGVDPETCMI-VFKNHWAQVVKI-LEKHDPLKNTQAKYGSIPPDEASAVQNYV 68
           LQ+AV  +  +P   ++  F  HW  +    +E  D  ++T AK   IP          +
Sbjct: 9   LQEAVGAR--EPSIDLLQAFVEHWKGITHYYIESTD--ESTPAKKTDIPWR--------L 56

Query: 69  EHMLFLLIEEQAKDAAMG---PILEFVVSENIMEKLFLWSLRREFTDETKIEQLKMYEML 125
           + ML +L+ E+ + AA G   P LE+++   I+E L     + E+    + +  + +  +
Sbjct: 57  KQMLDILVYEEQQQAAAGEAGPCLEYLLQHKILETLCTLG-KAEYPPGMRQQVFQFFSKV 115

Query: 126 VTQSHQPLLHHKPILKPLMMLLSSCSGTTTPTVEEK-LVVLLNQLCSILAKDPSIL 180
           + Q   PLLH+  + +P+  LL    GT + +V EK  V     LCS + +DP +L
Sbjct: 116 LAQVQHPLLHYLSVHRPVQKLL-RLGGTASGSVTEKEEVQFTTVLCSKIQQDPELL 170



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 26/92 (28%), Positives = 48/92 (52%)

Query: 849 FTGPFISVVLSKLENMLENSLHVNLLLIGIITQLASYPQPLLRSFLLNTNMVFQPSVRSL 908
           F G F+ V+  ++  +L+    +NL +  ++++LA +P P +  +LL+  +   P  RSL
Sbjct: 599 FEGHFLRVLFDRMSRILDQPYSLNLQVTSVLSRLALFPHPHIHEYLLDPYISLAPGCRSL 658

Query: 909 YQVLASVKNKIEQFASVERDFPGLLIQAQQYL 940
           + VL  V   + Q       FPG L+  ++ L
Sbjct: 659 FSVLVRVIGDLMQRIQRVPQFPGKLLLVRKQL 690


>gi|205277429 hypothetical protein LOC57700 isoform b [Homo sapiens]
          Length = 738

 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 58/246 (23%), Positives = 109/246 (44%), Gaps = 31/246 (12%)

Query: 196 LIFSLLIPFIHREGSVGQQARDALLFIMSLSAENTMVAHHIVENTYFCPVLATGLSGLYS 255
           L+ SLL      +G +  +A + L+ ++SL       A  + ++T  C +L   L+ LY 
Sbjct: 261 LVNSLLNLTRSPDGRIAVKACEGLMLLVSLP--EPAAAKCLTQSTCLCELLTDRLASLYK 318

Query: 256 SLPTKLEEKGEEWHCLL---------KDDWLLLP---SLVQFMNSLEFCNAVIQVAHPLI 303
           +LP  ++    E    +         K+D    P   +L+ F++  ++C+ +I+ A    
Sbjct: 319 ALPQSVDPLDIETVEAINWGLDSYSHKEDASAFPGKRALISFLSWFDYCDQLIKEAQKTA 378

Query: 304 RNQLVNYIYNGFLVPVLAPALHKVTVEEVMTTTAYLDLFLRSISEPALLEIFLRFILLHQ 363
              L   ++  F + V+ P L + +   ++T+TA L   +R ++   LL+  + FIL  Q
Sbjct: 379 AVALAKAVHERFFIGVMEPQLMQTSEMGILTSTALLHRIVRQVTSDVLLQEMVFFILGEQ 438

Query: 364 HENVHILDTLTSRINTPFR-------------LCVVSLALFRTLIGLHCEDVMLQLVLRY 410
            E     +TL      P R             + +++L +F  L+    E ++  LVLR 
Sbjct: 439 REP----ETLAEISRHPLRHRLIEHCDHISDEISIMTLRMFEHLLQKPNEHILYNLVLRN 494

Query: 411 LIPCNH 416
           L   N+
Sbjct: 495 LEERNY 500



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 30/122 (24%), Positives = 61/122 (50%), Gaps = 3/122 (2%)

Query: 64  VQNYVEHMLFLLIEEQ--AKDAAMGPILEFVVSENIMEKLFLWSLRREFTDETKIEQLKM 121
           + +++E ML +L++E+   +    GP +E+++   I+E L+    + +     K + L  
Sbjct: 52  IPSHLEQMLDILVQEENERESGETGPCMEYLLHHKILETLYTLG-KADCPPGMKQQVLVF 110

Query: 122 YEMLVTQSHQPLLHHKPILKPLMMLLSSCSGTTTPTVEEKLVVLLNQLCSILAKDPSILE 181
           Y  L+ +  QPLL H  + +P+  L+  C        E + +  L  +C+ L +DP ++ 
Sbjct: 111 YTKLLGRIRQPLLPHINVHRPVQKLIRLCGEVLATPTENEEIQFLCIVCAKLKQDPYLVN 170

Query: 182 LF 183
            F
Sbjct: 171 FF 172



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 24/93 (25%), Positives = 48/93 (51%)

Query: 849 FTGPFISVVLSKLENMLENSLHVNLLLIGIITQLASYPQPLLRSFLLNTNMVFQPSVRSL 908
           F G F+ V+  ++  +L+    VNL +  ++++L+ +P P +  +LL+  +   P  RSL
Sbjct: 631 FEGHFLKVLFDRMGRILDQPYDVNLQVTSVLSRLSLFPHPHIHEYLLDPYVNLAPGCRSL 690

Query: 909 YQVLASVKNKIEQFASVERDFPGLLIQAQQYLL 941
           + V+  V   +       +DF   L+  ++ LL
Sbjct: 691 FSVIVRVVGDLMLRIQRIQDFTPKLLLVRKRLL 723


>gi|205277427 hypothetical protein LOC57700 isoform a [Homo sapiens]
          Length = 765

 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 58/246 (23%), Positives = 109/246 (44%), Gaps = 31/246 (12%)

Query: 196 LIFSLLIPFIHREGSVGQQARDALLFIMSLSAENTMVAHHIVENTYFCPVLATGLSGLYS 255
           L+ SLL      +G +  +A + L+ ++SL       A  + ++T  C +L   L+ LY 
Sbjct: 261 LVNSLLNLTRSPDGRIAVKACEGLMLLVSLP--EPAAAKCLTQSTCLCELLTDRLASLYK 318

Query: 256 SLPTKLEEKGEEWHCLL---------KDDWLLLP---SLVQFMNSLEFCNAVIQVAHPLI 303
           +LP  ++    E    +         K+D    P   +L+ F++  ++C+ +I+ A    
Sbjct: 319 ALPQSVDPLDIETVEAINWGLDSYSHKEDASAFPGKRALISFLSWFDYCDQLIKEAQKTA 378

Query: 304 RNQLVNYIYNGFLVPVLAPALHKVTVEEVMTTTAYLDLFLRSISEPALLEIFLRFILLHQ 363
              L   ++  F + V+ P L + +   ++T+TA L   +R ++   LL+  + FIL  Q
Sbjct: 379 AVALAKAVHERFFIGVMEPQLMQTSEMGILTSTALLHRIVRQVTSDVLLQEMVFFILGEQ 438

Query: 364 HENVHILDTLTSRINTPFR-------------LCVVSLALFRTLIGLHCEDVMLQLVLRY 410
            E     +TL      P R             + +++L +F  L+    E ++  LVLR 
Sbjct: 439 REP----ETLAEISRHPLRHRLIEHCDHISDEISIMTLRMFEHLLQKPNEHILYNLVLRN 494

Query: 411 LIPCNH 416
           L   N+
Sbjct: 495 LEERNY 500



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 30/122 (24%), Positives = 61/122 (50%), Gaps = 3/122 (2%)

Query: 64  VQNYVEHMLFLLIEEQ--AKDAAMGPILEFVVSENIMEKLFLWSLRREFTDETKIEQLKM 121
           + +++E ML +L++E+   +    GP +E+++   I+E L+    + +     K + L  
Sbjct: 52  IPSHLEQMLDILVQEENERESGETGPCMEYLLHHKILETLYTLG-KADCPPGMKQQVLVF 110

Query: 122 YEMLVTQSHQPLLHHKPILKPLMMLLSSCSGTTTPTVEEKLVVLLNQLCSILAKDPSILE 181
           Y  L+ +  QPLL H  + +P+  L+  C        E + +  L  +C+ L +DP ++ 
Sbjct: 111 YTKLLGRIRQPLLPHINVHRPVQKLIRLCGEVLATPTENEEIQFLCIVCAKLKQDPYLVN 170

Query: 182 LF 183
            F
Sbjct: 171 FF 172



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 24/93 (25%), Positives = 48/93 (51%)

Query: 849 FTGPFISVVLSKLENMLENSLHVNLLLIGIITQLASYPQPLLRSFLLNTNMVFQPSVRSL 908
           F G F+ V+  ++  +L+    VNL +  ++++L+ +P P +  +LL+  +   P  RSL
Sbjct: 631 FEGHFLKVLFDRMGRILDQPYDVNLQVTSVLSRLSLFPHPHIHEYLLDPYVNLAPGCRSL 690

Query: 909 YQVLASVKNKIEQFASVERDFPGLLIQAQQYLL 941
           + V+  V   +       +DF   L+  ++ LL
Sbjct: 691 FSVIVRVVGDLMLRIQRIQDFTPKLLLVRKRLL 723


>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
           [Homo sapiens]
          Length = 916

 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 60/231 (25%), Positives = 97/231 (41%), Gaps = 17/231 (7%)

Query: 610 PIDPPKHIQEMKKNALLL-----FKGSYIEESDFQDDV--MVYRLCA--EKDSEDMKDSQ 660
           PI     IQ+ K  A  L     F    IEE+  +D+   M   L A  E+ +  MK+ +
Sbjct: 429 PITISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEK 488

Query: 661 EEAARPPAEA-QAEVQSVPINNGPLLSTQPETDSEEEWNRDNSDPFHSEPKEPKQEREPE 719
           +EAA    E  +AE + V     P+ +T PE   EEE  ++  +    E +E +  +  +
Sbjct: 489 KEAAEEKEEEPEAEEEEVAAKKSPVKATAPEV-KEEEGEKEEEEGQEEEEEEDEGAKSDQ 547

Query: 720 AAP-ESNSELASPAPEAEHSSNLTAAHPESEELIAQYDQIIKELDSGAEGLMEQNYPTPD 778
           A    S  E +S   E E     T A  E EE  A+ +   K+++  +E +  +     D
Sbjct: 548 AEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEE---KKVEEKSEEVATKEELVAD 604

Query: 779 PLLLTKEEEGKEESKGEKEKEGKKELEDE--EDDFDSFIAEMPAVETVPSP 827
             +   E+      K   E++GK  +     E+   S + + P  E   SP
Sbjct: 605 AKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSP 655



 Score = 34.7 bits (78), Expect = 0.48
 Identities = 47/193 (24%), Positives = 80/193 (41%), Gaps = 30/193 (15%)

Query: 649 AEKDSEDMKDSQEEAARPPAEAQAEVQSVPINNGPLLSTQPE--TDSEEEWNRDNSDPFH 706
           +EK+  + ++ + EA     EA+A+ +         ++T+ E   D++ E       P  
Sbjct: 559 SEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVP 618

Query: 707 SEP----------KEPKQEREPEAAPESNSELA--SPAPEA---EHSSNLTAAHPESEEL 751
             P          K P +E+     P+S  E    SP P++   E   +  +  P  E+ 
Sbjct: 619 KSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKA 678

Query: 752 IAQYDQI-IKELDSGAE-GLMEQNYPTPDPLLLTKEEEGKEESKGEKEKEGKKELEDEED 809
            +   +  ++E  S AE G  EQ           KEEE KE  +  KE++ +K+ E  +D
Sbjct: 679 KSPVPKSPVEEAKSKAEVGKGEQ-----------KEEEEKEVKEAPKEEKVEKKEEKPKD 727

Query: 810 DFDSFIAEMPAVE 822
             +   AE P  E
Sbjct: 728 VPEKKKAESPVKE 740



 Score = 32.7 bits (73), Expect = 1.8
 Identities = 45/187 (24%), Positives = 69/187 (36%), Gaps = 27/187 (14%)

Query: 660 QEEAARP-PAEAQAEVQSVPINNGPL--LSTQPETDSEEEWNRDNSDPFHSEPKEPKQER 716
           +E+   P P     E    P++  P+   +  P   S  E  +  ++    E KE +++ 
Sbjct: 649 EEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKE 708

Query: 717 EPEAAPESNSELASPAPEAEHSSNLTAAHPESEELIAQYDQIIKELDSGAEGLMEQNYPT 776
             EA  E   E     P+ +      A  P  EE +A+   I K +    E   ++    
Sbjct: 709 VKEAPKEEKVEKKEEKPK-DVPEKKKAESPVKEEAVAEVVTITKSVKVHLE---KETKEE 764

Query: 777 PDPLLLTKEEE------GKEESKGEK--------------EKEGKKELEDEEDDFDSFIA 816
             PL   KE+E      G EE   +K              E EGK+E+E E  +  S   
Sbjct: 765 GKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGRE 824

Query: 817 EMPAVET 823
           E   V T
Sbjct: 825 EEKGVVT 831


>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
           [Homo sapiens]
          Length = 540

 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 60/231 (25%), Positives = 97/231 (41%), Gaps = 17/231 (7%)

Query: 610 PIDPPKHIQEMKKNALLL-----FKGSYIEESDFQDDV--MVYRLCA--EKDSEDMKDSQ 660
           PI     IQ+ K  A  L     F    IEE+  +D+   M   L A  E+ +  MK+ +
Sbjct: 53  PITISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEK 112

Query: 661 EEAARPPAEA-QAEVQSVPINNGPLLSTQPETDSEEEWNRDNSDPFHSEPKEPKQEREPE 719
           +EAA    E  +AE + V     P+ +T PE   EEE  ++  +    E +E +  +  +
Sbjct: 113 KEAAEEKEEEPEAEEEEVAAKKSPVKATAPEV-KEEEGEKEEEEGQEEEEEEDEGAKSDQ 171

Query: 720 AAP-ESNSELASPAPEAEHSSNLTAAHPESEELIAQYDQIIKELDSGAEGLMEQNYPTPD 778
           A    S  E +S   E E     T A  E EE  A+ +   K+++  +E +  +     D
Sbjct: 172 AEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEE---KKVEEKSEEVATKEELVAD 228

Query: 779 PLLLTKEEEGKEESKGEKEKEGKKELEDE--EDDFDSFIAEMPAVETVPSP 827
             +   E+      K   E++GK  +     E+   S + + P  E   SP
Sbjct: 229 AKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSP 279



 Score = 34.7 bits (78), Expect = 0.48
 Identities = 47/193 (24%), Positives = 80/193 (41%), Gaps = 30/193 (15%)

Query: 649 AEKDSEDMKDSQEEAARPPAEAQAEVQSVPINNGPLLSTQPE--TDSEEEWNRDNSDPFH 706
           +EK+  + ++ + EA     EA+A+ +         ++T+ E   D++ E       P  
Sbjct: 183 SEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVP 242

Query: 707 SEP----------KEPKQEREPEAAPESNSELA--SPAPEA---EHSSNLTAAHPESEEL 751
             P          K P +E+     P+S  E    SP P++   E   +  +  P  E+ 
Sbjct: 243 KSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKA 302

Query: 752 IAQYDQI-IKELDSGAE-GLMEQNYPTPDPLLLTKEEEGKEESKGEKEKEGKKELEDEED 809
            +   +  ++E  S AE G  EQ           KEEE KE  +  KE++ +K+ E  +D
Sbjct: 303 KSPVPKSPVEEAKSKAEVGKGEQ-----------KEEEEKEVKEAPKEEKVEKKEEKPKD 351

Query: 810 DFDSFIAEMPAVE 822
             +   AE P  E
Sbjct: 352 VPEKKKAESPVKE 364



 Score = 32.7 bits (73), Expect = 1.8
 Identities = 45/187 (24%), Positives = 69/187 (36%), Gaps = 27/187 (14%)

Query: 660 QEEAARP-PAEAQAEVQSVPINNGPL--LSTQPETDSEEEWNRDNSDPFHSEPKEPKQER 716
           +E+   P P     E    P++  P+   +  P   S  E  +  ++    E KE +++ 
Sbjct: 273 EEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKE 332

Query: 717 EPEAAPESNSELASPAPEAEHSSNLTAAHPESEELIAQYDQIIKELDSGAEGLMEQNYPT 776
             EA  E   E     P+ +      A  P  EE +A+   I K +    E   ++    
Sbjct: 333 VKEAPKEEKVEKKEEKPK-DVPEKKKAESPVKEEAVAEVVTITKSVKVHLE---KETKEE 388

Query: 777 PDPLLLTKEEE------GKEESKGEK--------------EKEGKKELEDEEDDFDSFIA 816
             PL   KE+E      G EE   +K              E EGK+E+E E  +  S   
Sbjct: 389 GKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGRE 448

Query: 817 EMPAVET 823
           E   V T
Sbjct: 449 EEKGVVT 455


>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 45/176 (25%), Positives = 74/176 (42%), Gaps = 17/176 (9%)

Query: 650  EKDSEDMKDSQEEAARPPAEAQAEVQSVPINNGPLLSTQPETDSEEEWNRDNSDPFHSEP 709
            E+  E+   ++ E A    E  A    VP  +    S  PET+++E            E 
Sbjct: 1222 ERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKE-------PEVEEEE 1274

Query: 710  KEPKQEREPEAAPESNSELASPAPEAEHSSNLTAAHPESEELIAQYDQIIKELDSGAEGL 769
            ++P+   E   + E   EL  P PE E  +    A  +  +   + D     L+S  +  
Sbjct: 1275 EKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDD---GHLESTKKKE 1331

Query: 770  MEQNYPTPDPLLLTKEEEGKEES--KGEKEKEGKKELEDEEDDFDSFIAEMPAVET 823
            +E+  PT + +   KEE G +ES      +K  +K  + EE + DS   E P+ +T
Sbjct: 1332 LEEQ-PTREDV---KEEPGVQESFLDANMQKSREKIKDKEETELDS-EEEQPSHDT 1382



 Score = 31.2 bits (69), Expect = 5.3
 Identities = 38/169 (22%), Positives = 65/169 (38%), Gaps = 12/169 (7%)

Query: 650  EKDSEDMKDSQEEAARPPAEAQAEVQSVPINNGPLLSTQPETDSEEEWNRDNSDPFHSEP 709
            E + E+ K    E  R   E Q E++              ET   ++ + D+ D  H E 
Sbjct: 1269 EVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEE--DAAAETAQNDDHDADDEDDGHLES 1326

Query: 710  KEPKQEREPEAAPESNSEL--------ASPAPEAEHSSNLTAAHPESEELIAQYD-QIIK 760
             + K+  E     +   E         A+     E   +      +SEE    +D  ++ 
Sbjct: 1327 TKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVS 1386

Query: 761  ELDSGAEGLMEQNYPTPDPLLLTKEEEGKEESKGEKEK-EGKKELEDEE 808
            E  +G+E   E++  T + L+  KEEE    S+ + E  +  + L  EE
Sbjct: 1387 EQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEE 1435


>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 45/176 (25%), Positives = 74/176 (42%), Gaps = 17/176 (9%)

Query: 650  EKDSEDMKDSQEEAARPPAEAQAEVQSVPINNGPLLSTQPETDSEEEWNRDNSDPFHSEP 709
            E+  E+   ++ E A    E  A    VP  +    S  PET+++E            E 
Sbjct: 1222 ERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKE-------PEVEEEE 1274

Query: 710  KEPKQEREPEAAPESNSELASPAPEAEHSSNLTAAHPESEELIAQYDQIIKELDSGAEGL 769
            ++P+   E   + E   EL  P PE E  +    A  +  +   + D     L+S  +  
Sbjct: 1275 EKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDD---GHLESTKKKE 1331

Query: 770  MEQNYPTPDPLLLTKEEEGKEES--KGEKEKEGKKELEDEEDDFDSFIAEMPAVET 823
            +E+  PT + +   KEE G +ES      +K  +K  + EE + DS   E P+ +T
Sbjct: 1332 LEEQ-PTREDV---KEEPGVQESFLDANMQKSREKIKDKEETELDS-EEEQPSHDT 1382



 Score = 31.2 bits (69), Expect = 5.3
 Identities = 38/169 (22%), Positives = 65/169 (38%), Gaps = 12/169 (7%)

Query: 650  EKDSEDMKDSQEEAARPPAEAQAEVQSVPINNGPLLSTQPETDSEEEWNRDNSDPFHSEP 709
            E + E+ K    E  R   E Q E++              ET   ++ + D+ D  H E 
Sbjct: 1269 EVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEE--DAAAETAQNDDHDADDEDDGHLES 1326

Query: 710  KEPKQEREPEAAPESNSEL--------ASPAPEAEHSSNLTAAHPESEELIAQYD-QIIK 760
             + K+  E     +   E         A+     E   +      +SEE    +D  ++ 
Sbjct: 1327 TKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVS 1386

Query: 761  ELDSGAEGLMEQNYPTPDPLLLTKEEEGKEESKGEKEK-EGKKELEDEE 808
            E  +G+E   E++  T + L+  KEEE    S+ + E  +  + L  EE
Sbjct: 1387 EQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEE 1435


>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 45/176 (25%), Positives = 74/176 (42%), Gaps = 17/176 (9%)

Query: 650  EKDSEDMKDSQEEAARPPAEAQAEVQSVPINNGPLLSTQPETDSEEEWNRDNSDPFHSEP 709
            E+  E+   ++ E A    E  A    VP  +    S  PET+++E            E 
Sbjct: 1222 ERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKE-------PEVEEEE 1274

Query: 710  KEPKQEREPEAAPESNSELASPAPEAEHSSNLTAAHPESEELIAQYDQIIKELDSGAEGL 769
            ++P+   E   + E   EL  P PE E  +    A  +  +   + D     L+S  +  
Sbjct: 1275 EKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDD---GHLESTKKKE 1331

Query: 770  MEQNYPTPDPLLLTKEEEGKEES--KGEKEKEGKKELEDEEDDFDSFIAEMPAVET 823
            +E+  PT + +   KEE G +ES      +K  +K  + EE + DS   E P+ +T
Sbjct: 1332 LEEQ-PTREDV---KEEPGVQESFLDANMQKSREKIKDKEETELDS-EEEQPSHDT 1382



 Score = 31.2 bits (69), Expect = 5.3
 Identities = 38/169 (22%), Positives = 65/169 (38%), Gaps = 12/169 (7%)

Query: 650  EKDSEDMKDSQEEAARPPAEAQAEVQSVPINNGPLLSTQPETDSEEEWNRDNSDPFHSEP 709
            E + E+ K    E  R   E Q E++              ET   ++ + D+ D  H E 
Sbjct: 1269 EVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEE--DAAAETAQNDDHDADDEDDGHLES 1326

Query: 710  KEPKQEREPEAAPESNSEL--------ASPAPEAEHSSNLTAAHPESEELIAQYD-QIIK 760
             + K+  E     +   E         A+     E   +      +SEE    +D  ++ 
Sbjct: 1327 TKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVS 1386

Query: 761  ELDSGAEGLMEQNYPTPDPLLLTKEEEGKEESKGEKEK-EGKKELEDEE 808
            E  +G+E   E++  T + L+  KEEE    S+ + E  +  + L  EE
Sbjct: 1387 EQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEE 1435


>gi|40807447 papillary renal cell carcinoma translocation-associated
           gene product isoform 1 [Homo sapiens]
          Length = 491

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 71/297 (23%), Positives = 112/297 (37%), Gaps = 42/297 (14%)

Query: 545 VSSACPVFGLPQQLPRKTGPQLA-PRKDKSQTELEWDD-SYDTGISSGADVGSPGPYDDL 602
           +  A P  GLP+   RK   ++A P   K  ++ E D+ +    I  G+  G+       
Sbjct: 126 IGGAGPPLGLPKPKKRKEPVKIAAPELHKGDSDSEEDEPTKKKTILQGSSEGT------- 178

Query: 603 EVSGPPAPIDPPKHIQEMKKNALLLFKGSYIEESDFQDDVMVYRLCAEKDSEDMKD--SQ 660
              G  A +  PK++   + N LLL      + SD   D    RL ++  +  +      
Sbjct: 179 ---GLSALLPQPKNLTVKETNRLLLPHAFSRKPSDGSPDTKPSRLASKTKTSSLAPVVGT 235

Query: 661 EEAARPPAEAQAEVQSVPINNGPLLSTQPETDSEEEWNRDNSDPFHSEPKEPKQEREPEA 720
                 P+  +A  +S  +     + TQ E DS+EE   +N      + + P  E  P  
Sbjct: 236 TTTTPSPSAIKAAAKSAALQVTKQI-TQEEDDSDEEVAPENFFSLPEKAEPPGVEPYPYP 294

Query: 721 APESNSELASPAPEAEHSSNLTAAHPESEELIA----------------QYDQIIKELDS 764
            P    EL  P  E E +    AA+   E  +A                 Y+Q     D+
Sbjct: 295 IPTVPEEL-PPGTEPEPAFQDDAANAPLEFKMAAGSSGAPWMPKPGDDYSYNQFSTYGDA 353

Query: 765 GAEGLMEQN------YPTPDPLLLTKEEEGKEES----KGEKEKEGKKELEDEEDDF 811
            A G   Q+      YP  DP L+  +E   + S    +  K  +GK+    EE +F
Sbjct: 354 NAAGAYYQDYYSGGYYPAQDPALVPPQEIAPDASFIDDEAFKRLQGKRNRGREEINF 410


>gi|125656165 THO complex 2 [Homo sapiens]
          Length = 1593

 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 41/165 (24%), Positives = 70/165 (42%), Gaps = 11/165 (6%)

Query: 651  KDSEDMKDSQEEAARPPAEAQAEVQSVPINNGPLLSTQP-ETDSEEEWNRDNSDPFHSEP 709
            K+     D ++E  +   +A+ E     + N    STQ  E + E    RD +    S+ 
Sbjct: 1318 KERTPKSDKEKEKFKKEEKAKDEKFKTTVPNAESKSTQEREREKEPSRERDIAKEMKSKE 1377

Query: 710  KEPKQEREPEA----APESNSELASPAPEAEHSSNLTAAHPESEELIAQYDQIIKELDSG 765
                 E+ P +    +P   S++  P PE E        HP         D +I+  +S 
Sbjct: 1378 NVKGGEKTPVSGSLKSPVPRSDI--PEPEREQKRRKIDTHPSPSHSSTVKDSLIELKESS 1435

Query: 766  AEGLMEQNYPTPDPLLLTKEEE-GKEESKGEKEKEGKKELEDEED 809
            A+  +     TP PL  +KE E  K++    +E+  ++E +DE+D
Sbjct: 1436 AKLYINH---TPPPLSKSKEREMDKKDLDKSRERSREREKKDEKD 1477


>gi|7019419 guanine nucleotide binding protein-like 2 (nucleolar)
           [Homo sapiens]
          Length = 731

 Score = 43.9 bits (102), Expect = 8e-04
 Identities = 39/145 (26%), Positives = 73/145 (50%), Gaps = 19/145 (13%)

Query: 673 EVQSVPINNGPLLSTQPETDSEEEWNRDNSDPFHSEPKEPKQEREPEAAPESNSELASPA 732
           ++  VP  +G  L     +D EEE          S+ +E +QE++ + A ES+SE     
Sbjct: 535 KINVVPQFSGDDLVPVEVSDLEEELES------FSDEEEEEQEQQRDDAEESSSE----- 583

Query: 733 PEAEHSSNLTAAHPES-EELIAQYDQIIKELDSG-------AEGLMEQNYPTPDPLLLTK 784
           PE E+  N T A  ++ +E IA+Y + + +  +        ++GL E+ +  P+    T 
Sbjct: 584 PEEENVGNDTKAVIKALDEKIAKYQKFLDKAKAKKFSAVRISKGLSEKIFAKPEEQRKTL 643

Query: 785 EEEGKEESKGEKEKEGKKELEDEED 809
           EE+  + +  +K K+ K + E+E++
Sbjct: 644 EEDVDDRAPSKKGKKRKAQREEEQE 668


>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
            sapiens]
          Length = 1130

 Score = 43.5 bits (101), Expect = 0.001
 Identities = 61/291 (20%), Positives = 104/291 (35%), Gaps = 58/291 (19%)

Query: 595  SPGPYDDLEVSGPPAP----IDPPKHIQE----------MKKNALLLFKGSYIEESDFQD 640
            +PGP        PP P    + PP+ + E          ++++  ++   S  EE + ++
Sbjct: 835  APGPLPPPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEE 894

Query: 641  DVMVYRLCAEKDSEDMKDSQEEAARPPAEAQAEVQSVPIN----NGPLLSTQPETDSEEE 696
            +        E++ ED ++ +E+      E + E +          G L   + E D EEE
Sbjct: 895  EEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEE 954

Query: 697  WNRDNSDPFH--------SEPKEPKQEREPEAAPESNSELASPAPEAEHSSNLTAAHPES 748
               +  +            E   P     P   P  +     P PE E    L    P +
Sbjct: 955  EELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGT 1014

Query: 749  E-------------ELIAQYDQIIKELDSGAEG-----LMEQNYPTPDPLLLTKEEEGKE 790
            E             E +    ++ +E +S A G     L+E+    P  LL  + E+G +
Sbjct: 1015 EEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSD 1074

Query: 791  ----------ESKGEKEKEGKKELEDEEDDFDSFIAEM----PAVETVPSP 827
                      E + E E E +   E E+DD  + +A+     P  E  P P
Sbjct: 1075 KVQPPPETPAEEEMETETEAEALQEKEQDDTAAMLADFIDCPPDDEKPPPP 1125



 Score = 37.0 bits (84), Expect = 0.097
 Identities = 37/148 (25%), Positives = 61/148 (41%), Gaps = 17/148 (11%)

Query: 664 ARPPAEAQAEVQSVPINNGPLLSTQPETDSEEEWNRDNSDPFHSEPKEPKQEREPEAAPE 723
           A PP  A+ E + +P   GPL    P              P       P  +  PE  P 
Sbjct: 819 ASPPVPAKEEPEELPAAPGPLPPPPPPPP-----------PVPGPVTLPPPQLVPEGTPG 867

Query: 724 SNSELASPAPEAEHSS-NLTAAHPESEELIAQYDQIIKELDSGAEGLMEQNYPTPDPLLL 782
                  PA E + +  N+ ++  E EE   + ++  +E +   E   E+     +    
Sbjct: 868 GGGP---PALEEDLTVININSSDEEEEEEEEEEEE--EEEEEEEEEDFEEEEEDEEEYFE 922

Query: 783 TKEEEGKEESKGEKEKEGKKELEDEEDD 810
            +EEE +E  +  +E+EG+ E E+EE+D
Sbjct: 923 EEEEEEEEFEEEFEEEEGELEEEEEEED 950



 Score = 35.4 bits (80), Expect = 0.28
 Identities = 32/127 (25%), Positives = 49/127 (38%), Gaps = 21/127 (16%)

Query: 709 PKEPKQEREPEAAPESNSELASPAPEAEHSSNLTAAH-----------PESEELIAQYDQ 757
           P  P     P  AP      + P P  E    L AA            P    +     Q
Sbjct: 800 PPPPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPPPPPPPVPGPVTLPPPQ 859

Query: 758 IIKELDSGAEG-------LMEQNYPTPDPLLLTKEEEGKEESKGEKEKEGKKELEDEEDD 810
           ++ E   G  G       L   N  + D     +EEE +EE + E+E+E +++ E+EE+D
Sbjct: 860 LVPEGTPGGGGPPALEEDLTVININSSDE---EEEEEEEEEEEEEEEEEEEEDFEEEEED 916

Query: 811 FDSFIAE 817
            + +  E
Sbjct: 917 EEEYFEE 923


>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
          Length = 793

 Score = 43.5 bits (101), Expect = 0.001
 Identities = 40/180 (22%), Positives = 68/180 (37%), Gaps = 18/180 (10%)

Query: 645 YRLCAEKDSEDMKDSQEEAARPP-----------------AEAQAEVQSVPINNGPLLST 687
           +R   E   ED +  +EE  +P                   E+Q E   + + NG + S 
Sbjct: 177 WRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSE 236

Query: 688 QPETDSEEEWNRDNSDPFHSEPKEPKQEREPEAAPESNSELASPAPEAEHSSNLTAAHPE 747
           +P+ + E E   D         +E K+  E E A     E      E +       A  E
Sbjct: 237 EPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIE 296

Query: 748 SEELIAQYDQIIKELDSGAEGLMEQNYPTPDPLLLTKEEEGKEESKGEKEKEGKKELEDE 807
           +EE  A  ++  +E +   E + E+     +     KEEE +   + ++ KE +K   +E
Sbjct: 297 AEEKAAAQERERREAEE-RERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEE 355


>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
          Length = 2400

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 44/179 (24%), Positives = 81/179 (45%), Gaps = 27/179 (15%)

Query: 649  AEKDSEDMKDSQEEAARPPAEAQAEVQSVPINNGPLLSTQPETDSEEEWNRDNSDPFHSE 708
            A+ +SED++  + E     AE +A+ +S  +        QP+++ EE      +     E
Sbjct: 1993 AQPESEDVEAPEAEGEMQEAEEEAQPESDGVE------AQPKSEGEE------AQEVEGE 2040

Query: 709  PKEPKQEREPEA----APESNSELASPAPEAEHSSNLTAAHPESEELIAQYDQIIKELDS 764
             ++ + + +PE+    APE+  E      E + +     AHPESE++ AQ  +   + +S
Sbjct: 2041 TQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEG--EAHPESEDVDAQEAEGEAQPES 2098

Query: 765  ------GAEGLMEQNYPTPDPLLLTKEEEGKEESKGEKEKEGKKELEDEEDDFDSFIAE 817
                   AEG  ++      P     E E + ES+G +  E + E + E +  ++  AE
Sbjct: 2099 EGVEAPEAEGEAQKAEGIEAP---ETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAE 2154



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 55/195 (28%), Positives = 80/195 (41%), Gaps = 25/195 (12%)

Query: 650  EKDSEDMKDSQEEAARPPAEAQAEVQSV--PINNGPLLSTQPETDSEEEWNRDNSDPFHS 707
            E + E  K    EA     EAQ E + +  P   G     QPE++  E  + +      S
Sbjct: 2105 EAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEG---EAQPESEGVEAQDAEGEAQPES 2161

Query: 708  EPKEPKQEREPEAAPESNSELASPAPEAEHSSNLTAAHPESEELIAQY--DQIIKELDSG 765
            E  E  QE E EA PE        APEAE       A PESE + A     +   EL+ G
Sbjct: 2162 EGIEA-QEAEEEAQPELEGV---EAPEAEGE-----AQPESEGIEAPEAEGEAQPELE-G 2211

Query: 766  AEGLMEQNYPTPDPL-LLTKEEEGKEESKGEKEKEGKKE-------LEDEEDDFDSFIAE 817
             E    +    P+P  + T E EG+ + + E E +G+K+        + + ++     + 
Sbjct: 2212 VEAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEASESSSP 2271

Query: 818  MPAVETVPSPFVGRD 832
            +P     P P  G D
Sbjct: 2272 VPEDRPTPPPSPGGD 2286



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 72/305 (23%), Positives = 113/305 (37%), Gaps = 50/305 (16%)

Query: 561  KTGPQLAPRKDKSQTELEWDDSYDTGISSGADVGSPGPYDDLEVSGPPAPIDPPK---HI 617
            +TG Q +  +D  Q E       D G S GA+ G   P  + E       ++ P+     
Sbjct: 1802 ETGGQGSGHEDNLQGEAAAGGDQDPGQSDGAE-GIEAPEAEGEAQPESEGVEAPEAEGDA 1860

Query: 618  QEMKKNALLLFKGSYIEESDFQDDVMVYRLCAEKDSEDMKDSQEE---------AARPPA 668
            QE +  A    +     E++ +         A+ +SED++  + E         A  P A
Sbjct: 1861 QEAEGEAQPESEDVEAPEAEGE---------AQPESEDVETPEAEWEVQPESEGAEAPEA 1911

Query: 669  E--AQAEVQSV----------PINNGPLLSTQPETDSEEEWNRDNSDPFHSEPKEPKQER 716
            E  AQ E +SV          P + G       E   E E  +   +    E +E ++E 
Sbjct: 1912 EKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAE-GQTQPESEVIESQEAEEEA 1970

Query: 717  EPEAAPESNSELASPAPEAEHSSNLTAAHPESEELIAQYDQIIKELDSGAEGLMEQNYPT 776
            +PE+      E+     EAE       A PESE++ A            AEG M++    
Sbjct: 1971 QPESEDVEALEVEVETQEAEGE-----AQPESEDVEA----------PEAEGEMQEAEEE 2015

Query: 777  PDPLLLTKEEEGKEESKGEKEKEGKKELEDEEDDFDSFIAEMPAVETVPSPFVGRDEAAF 836
              P     E + K E +  +E EG+ +  + +   +S   E P  E       G  + A 
Sbjct: 2016 AQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAE 2075

Query: 837  ASRHP 841
               HP
Sbjct: 2076 GEAHP 2080



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 52/187 (27%), Positives = 78/187 (41%), Gaps = 31/187 (16%)

Query: 650  EKDSEDMKDSQEEAARPPAEAQAEVQSVPINNGPLLSTQPETDSEEEWNRDNSDPFHSEP 709
            E D  +  +++EEA     EA+ EVQ       P        ++E E   ++      E 
Sbjct: 2051 ESDGVEAPEAEEEAQ----EAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEA 2106

Query: 710  KEPKQEREPEAAPESNSELASP------APEAEHSSNLTAAHPESEELIAQYDQIIKELD 763
            +   Q+ E   APE+  E A P      APEAE       A PESE + AQ  +   E  
Sbjct: 2107 EGEAQKAEGIEAPETEGE-AQPESEGIEAPEAEGE-----AQPESEGVEAQDAE--GEAQ 2158

Query: 764  SGAEGLMEQNYPTPDPLLLTKEEEGKEESKGEKEKEGKKELEDEEDDFDSFIAE---MPA 820
              +EG+  Q            EEE + E +G +  E + E + E +  ++  AE    P 
Sbjct: 2159 PESEGIEAQE----------AEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPE 2208

Query: 821  VETVPSP 827
            +E V +P
Sbjct: 2209 LEGVEAP 2215



 Score = 32.0 bits (71), Expect = 3.1
 Identities = 39/157 (24%), Positives = 62/157 (39%), Gaps = 30/157 (19%)

Query: 648  CAEKDSEDMKDSQEEAARPPAEAQAEVQSVPINNGPLLSTQPETDSEEEWNRDNSDPFHS 707
            CA  + E  +DS+E+ A    E  AE            + Q E   EE       +    
Sbjct: 1269 CATNEDEAERDSEEQRASSNLEQLAE-----------NTVQEEVQLEETKEGTEGEGLQE 1317

Query: 708  EPKEPKQEREPEAAPESNSELASPAPEAEHSSNLTAAHPESEELIAQYDQIIKELDSGAE 767
            E  + ++ +  E   E   +L       E +        + EE  AQ ++I    ++G E
Sbjct: 1318 EAVQLEETKTEEGLQEEGVQL-------EETKETEGEGQQEEE--AQLEEI---EETGGE 1365

Query: 768  GLMEQNYPTPDPLLLTKEEEGKEES-KGEKEKEGKKE 803
            GL E+       + L + +EG E   +GE  +EG KE
Sbjct: 1366 GLQEEG------VQLEEVKEGPEGGLQGEALEEGLKE 1396


>gi|7657138 golgi integral membrane protein 4 [Homo sapiens]
          Length = 696

 Score = 42.7 bits (99), Expect = 0.002
 Identities = 42/193 (21%), Positives = 81/193 (41%), Gaps = 11/193 (5%)

Query: 629 KGSYIEESDFQDDVMVYRLCAEKDSEDMKDSQEEAAR---PPAEA-QAEVQSVPINNGPL 684
           +G+Y  ++  QD+       AE D  +  + +E+  R   P +EA +A V+ +   + P 
Sbjct: 503 EGAYERDNQHQDE-------AEGDPGNRHEPREQGPREADPESEADRAAVEDINPADDPN 555

Query: 685 LSTQPETDSEEEWNRDNSDPFHSEPKEPKQEREPEAAPESNSELASPAPEAEHSSNLTAA 744
              + E +  E+   +N    + E K+  Q++E     E      +P  + ++       
Sbjct: 556 NQGEDEFEEAEQVREENLPDENEEQKQSNQKQENTEVEEHLVMAGNPDQQEDNVDEQYQE 615

Query: 745 HPESEELIAQYDQIIKELDSGAEGLMEQNYPTPDPLLLTKEEEGKEESKGEKEKEGKKEL 804
             E E      ++  +EL+  AE    +N    D      EE+   +    K +E   E 
Sbjct: 616 EAEEEVQEDLTEEKKRELEHNAEETYGENDENTDDKNNDGEEQEVRDDNRPKGREEHYEE 675

Query: 805 EDEEDDFDSFIAE 817
           E+EE++  + +AE
Sbjct: 676 EEEEEEDGAAVAE 688



 Score = 31.6 bits (70), Expect = 4.1
 Identities = 30/143 (20%), Positives = 60/143 (41%), Gaps = 12/143 (8%)

Query: 667 PAEAQAEVQSVPINNGPLLSTQPETDSEEEWNRDNSDPFHSEPKEPKQEREPEAAPESNS 726
           PAE Q   Q      G   + +  T   +E +R+N D + +    P +  + +    ++ 
Sbjct: 252 PAEQQNVTQVAHSPQGYNTAREKPTREVQEVSRNN-DVWQNHEAVPGRAEDTKLYAPTHK 310

Query: 727 ELASPAPEAEHSSNLTAAHPESEELIAQYDQIIKELD----SGAEGLMEQNYPTPDPLLL 782
           E    AP       +    PE  ++  ++ + ++E +      AE L E++ P+P     
Sbjct: 311 EAEFQAPPEPIQQEVERREPEEHQVEEEHRKALEEEEMEQVGQAEHLEEEHDPSP----- 365

Query: 783 TKEEEGKEESKGEKEKEGKKELE 805
             EE+ +E  +  +++E    LE
Sbjct: 366 --EEQDREWKEQHEQREAANLLE 386


>gi|33188449 serine/arginine-rich protein-specific kinase 2 isoform
           a [Homo sapiens]
          Length = 699

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 44/182 (24%), Positives = 76/182 (41%), Gaps = 36/182 (19%)

Query: 640 DDVMVYRLCAEKDSEDMKDSQEEAARPPAEAQAEVQSVPINNGPLLSTQPETDSEEEWNR 699
           DD  V R+ AE       + Q+  A PP+             G  +ST P+     + ++
Sbjct: 236 DDAYVRRMAAEAT-----EWQKAGAPPPS-------------GSAVSTAPQQKPIGKISK 277

Query: 700 DNSDPFHSEPKEPKQEREPEAAPESNSELASPAPEAEHS---SNLTAAHPESEELIAQYD 756
           +          + KQ+R+ E   +   E+     EAE      N+T+A P +++   +Y 
Sbjct: 278 NKKKKL-----KKKQKRQAELLEKRLQEIEELEREAERKIIEENITSAAPSNDQ-DGEYC 331

Query: 757 QIIKELDSGAEGLMEQNYPTPDPLLLTKEEEGKEESKGEKEKEGKKELEDEEDDFDSFIA 816
             +K   +G E   E           T ++ G+ E + EKE   K+ +E +EDD D  +A
Sbjct: 332 PEVKLKTTGLEEAAEAE---------TAKDNGEAEDQEEKEDAEKENIEKDEDDVDQELA 382

Query: 817 EM 818
            +
Sbjct: 383 NI 384


>gi|33188447 serine/arginine-rich protein-specific kinase 2 isoform
           b [Homo sapiens]
          Length = 688

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 44/182 (24%), Positives = 76/182 (41%), Gaps = 36/182 (19%)

Query: 640 DDVMVYRLCAEKDSEDMKDSQEEAARPPAEAQAEVQSVPINNGPLLSTQPETDSEEEWNR 699
           DD  V R+ AE       + Q+  A PP+             G  +ST P+     + ++
Sbjct: 225 DDAYVRRMAAEAT-----EWQKAGAPPPS-------------GSAVSTAPQQKPIGKISK 266

Query: 700 DNSDPFHSEPKEPKQEREPEAAPESNSELASPAPEAEHS---SNLTAAHPESEELIAQYD 756
           +          + KQ+R+ E   +   E+     EAE      N+T+A P +++   +Y 
Sbjct: 267 NKKKKL-----KKKQKRQAELLEKRLQEIEELEREAERKIIEENITSAAPSNDQ-DGEYC 320

Query: 757 QIIKELDSGAEGLMEQNYPTPDPLLLTKEEEGKEESKGEKEKEGKKELEDEEDDFDSFIA 816
             +K   +G E   E           T ++ G+ E + EKE   K+ +E +EDD D  +A
Sbjct: 321 PEVKLKTTGLEEAAEAE---------TAKDNGEAEDQEEKEDAEKENIEKDEDDVDQELA 371

Query: 817 EM 818
            +
Sbjct: 372 NI 373


>gi|54112403 chromodomain helicase DNA binding protein 7 [Homo
           sapiens]
          Length = 2997

 Score = 42.0 bits (97), Expect = 0.003
 Identities = 42/192 (21%), Positives = 76/192 (39%), Gaps = 14/192 (7%)

Query: 674 VQSVPINNGPLLSTQPETDSEE--EWNRDNSDPFH----SEPKEPKQEREPEAAPESNSE 727
           V +  +N   L  +Q E   ++  +  +D  +P       EPKEPK  + P+   E   +
Sbjct: 624 VDNQELNRNSLDGSQEEKKKKKRSKAKKDPKEPKEPKEKKEPKEPKTPKAPKIPKEPKEK 683

Query: 728 LASPAPEAEHSSNLTAAHPESEELIAQYDQIIKELDSGAEGLMEQNYPTPDPLLLTKEEE 787
            A  A     SS  ++      E  A   ++ K    G+E       P P P     E+ 
Sbjct: 684 KAKTATPKPKSSKKSSNKKPDSEASALKKKVNKGKTEGSENSDLDKTPPPSPPPEEDEDP 743

Query: 788 GKEESKGEKEKEGKKELEDEEDDFDSFIAEMPAVETVPSPFVGRDEAAFASRHPVRTQST 847
           G ++ +  ++ + K+  ED E        ++   E   +   GRD  +  S+   + +S 
Sbjct: 744 GVQKRRSSRQVKRKRYTEDLE-------FKISDEEADDADAAGRDSPSNTSQSE-QQESV 795

Query: 848 PFTGPFISVVLS 859
              GP +  ++S
Sbjct: 796 DAEGPVVEKIMS 807



 Score = 30.4 bits (67), Expect = 9.1
 Identities = 29/147 (19%), Positives = 59/147 (40%), Gaps = 19/147 (12%)

Query: 648  CAEKDSEDMKDSQEEAARPPAEAQA-----EVQSVPIN----NGPLLSTQPETDSEEEWN 698
            C  K+ E+  D   + ++   EA+A     E++ V +     +  +     E D EE+  
Sbjct: 2187 CEGKEEEEETDGSGKESKQECEAEASSVKNELKGVEVGADTGSKSISEKGSEEDEEEKLE 2246

Query: 699  RDNSDPFHSEPKEPKQEREPEAAPESNSELASPAPEAEHSSNLTAAHPESEELIAQ---- 754
             D+     S+P+     R      ESN+ +++   E      +    P   +L+ +    
Sbjct: 2247 DDDKSEESSQPEAGAVSRGKNFDEESNASMSTARDETRDGFYMEDGDPSVAQLLHERTFA 2306

Query: 755  -----YDQI-IKELDSGAEGLMEQNYP 775
                  D++ I  LD+  E +++  +P
Sbjct: 2307 FSFWPKDRVMINRLDNICEAVLKGKWP 2333


>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
            [Homo sapiens]
          Length = 2073

 Score = 42.0 bits (97), Expect = 0.003
 Identities = 49/225 (21%), Positives = 91/225 (40%), Gaps = 40/225 (17%)

Query: 626  LLFKGSYIEESDFQDDVMVYRL-----CAEKDSEDMKDSQEEAARPPAEAQA-------- 672
            +L   + + E + + +    RL     C EK+ +++  ++  + + PA+ Q+        
Sbjct: 990  ILISNAAVSEEEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSP 1049

Query: 673  EVQSVPINNGPLLSTQPETDSEEEWNRDNSDPFHSEPK---EPKQEREPEAAPESNSELA 729
            E + V    G LL    E+  EEE   D  +    E +   E ++E E E   E N + +
Sbjct: 1050 ESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSS 1109

Query: 730  SPAPEAEHSSNLTAAHP-----------------ESEELIAQYDQIIKEL--DSGAEGLM 770
             P      S  +    P                  + E I++  +++ E   +S  E  M
Sbjct: 1110 PPRLTKPQSVAIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPM 1169

Query: 771  EQNYPTPDPLLLTKEEEGKEE--SKGEKEKEGKKELEDEEDDFDS 813
             Q  PT +   +  EE+G++    K  + + GKK   +EE+  D+
Sbjct: 1170 PQLEPTCE---IEVEEDGRKPVLRKAFQHQPGKKRQTEEEEGKDN 1211



 Score = 33.9 bits (76), Expect = 0.82
 Identities = 58/282 (20%), Positives = 105/282 (37%), Gaps = 24/282 (8%)

Query: 541  EEGSVSSACPVFGLPQQLPRKTGPQLAPRKDKSQTELEWDDSYDTGISSGADVGSPGPYD 600
            EE ++ S+ P    PQ +  K       +K + +     + S  T   S        P+D
Sbjct: 1102 EEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFD 1161

Query: 601  DLEVSGPPAPIDPPKHIQEMKKNALLLFKGSY---------IEESDFQDDVMVYRL--CA 649
            + +   P   ++P   I+  +     + + ++          EE + +D+        C 
Sbjct: 1162 NSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKKRQTEEEEGKDNHCFKNADPCR 1221

Query: 650  EKDSEDMKDSQEEAARPPAEAQAEVQSVPINNGPLLSTQPETDSEEEWNRDNSDPFHSEP 709
               ++D  + +E +   P   + + Q  P      LS   +    +   + N       P
Sbjct: 1222 NNMNDDSSNLKEGSKDNPEPLKCK-QVWPKGTKRGLSKWRQNKERKTGFKLNLYTPPETP 1280

Query: 710  KEPKQEREPEAAPESNSELASPAP---EAEHSSNLTAAHPESEELIAQYDQIIKELDSGA 766
             EP ++   E   E++    SP+P   E E      A  P+ E    +    +    S  
Sbjct: 1281 MEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLPQEENRREETCAPVSPNTSPG 1340

Query: 767  EGLMEQNYPTPDPLLLTKEEEGKEESKGEKEKEGKKELEDEE 808
            E       P  D   L K EE +EE + E+E+E ++E E+EE
Sbjct: 1341 EK------PEDD---LIKPEEEEEEEEEEEEEEEEEEGEEEE 1373



 Score = 33.5 bits (75), Expect = 1.1
 Identities = 36/177 (20%), Positives = 64/177 (36%), Gaps = 26/177 (14%)

Query: 650  EKDSEDMKDSQEEAARPPAEAQAEVQSVPINNGPLLSTQPETDSEEEWNR--DNSDPFHS 707
            E++ E+ ++ +EE      E    V+  P         +PE  +E+E +   D+ +    
Sbjct: 1354 EEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEE 1413

Query: 708  EPKEPKQEREPEAAPESNSELASPAPEAEH-----------------SSNLTAAHPESE- 749
            E +EP    + +A  E +S + S   E E                    N+   H   E 
Sbjct: 1414 EDEEPSHNEDHDADDEDDSHMESAEVEKEELPRESFKEVLENQETFLDLNVQPGHSNPEV 1473

Query: 750  ------ELIAQYDQIIKELDSGAEGLMEQNYPTPDPLLLTKEEEGKEESKGEKEKEG 800
                  +L A  +   KEL    E + E +   P      K+++   +    + KEG
Sbjct: 1474 LMDCGVDLTASCNSEPKELAGDPEAVPESDEEPPPGEQAQKQDQKNSKEVDTEFKEG 1530



 Score = 32.3 bits (72), Expect = 2.4
 Identities = 27/107 (25%), Positives = 45/107 (42%), Gaps = 11/107 (10%)

Query: 654  EDMKDSQEEAARPPAEAQAEVQSVPINNGPLLSTQPETD---SEEEWNRDNSDPFHSEPK 710
            E++K++ E A  P  E + E    P++       +PE D    EEE   +  +    E +
Sbjct: 1309 EEVKETGE-ALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEE 1367

Query: 711  EPKQE-------REPEAAPESNSELASPAPEAEHSSNLTAAHPESEE 750
            E ++E       ++P+ A     E    + E E S+ L     E EE
Sbjct: 1368 EGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEE 1414



 Score = 31.6 bits (70), Expect = 4.1
 Identities = 30/159 (18%), Positives = 64/159 (40%), Gaps = 21/159 (13%)

Query: 683  PLLSTQPETDSEEEWNRDNSDPFHSEPKEPKQEREPEAAPESNSELASPAPEAEHSSNLT 742
            P+L +      EE      ++    +    ++E +   +  +NS     +P    S N  
Sbjct: 989  PILISNAAVSEEEREAEKEAERLMEQASCWEKEEQEILSTRANSR---QSPAKVQSKNKY 1045

Query: 743  AAHPESEELIAQYDQIIKELDSGAEGLMEQNYPTPDPLLLTKEEEGKEESKGEKEKEGKK 802
               PES  +  +  Q+++        L +++           EEE +EE + E+E+E ++
Sbjct: 1046 LHSPESRPVTGERGQLLE--------LSKES----------SEEEEEEEDEEEEEEEEEE 1087

Query: 803  ELEDEEDDFDSFIAEMPAVETVPSPFVGRDEAAFASRHP 841
            E ++EE++ +    E   +++ P         A   + P
Sbjct: 1088 EEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRP 1126


>gi|23503317 coiled-coil domain containing 96 [Homo sapiens]
          Length = 555

 Score = 42.0 bits (97), Expect = 0.003
 Identities = 44/160 (27%), Positives = 65/160 (40%), Gaps = 12/160 (7%)

Query: 658 DSQEEAARPPAEAQAEVQSVPINNGPLLSTQPETDSEEEWNRDNSDPFHSEPKEPKQERE 717
           D +  AARP     +         G L S +PE + EE+           + + PK    
Sbjct: 17  DGESLAARPSKIKASSGPPTSPEPGELES-EPEEEEEEQAASQGGTAADEQAEAPKGLTA 75

Query: 718 PEAA----PESNSELASPAPEAEHSSNLTAAHPESEELIAQYDQI-----IKELDSGAEG 768
            EAA    P      A P PE E  + + A  P   E  A  +++      +EL+  AEG
Sbjct: 76  AEAAGEEGPGEPGRPAEPQPEPEEPAEVGAEEPAQPEPGAGPEELEAEAGAEELEQAAEG 135

Query: 769 LMEQNYPTPDPLLLTKEEEGKEESKGEKEK-EGKKELEDE 807
             E  +    PL    EEE     + E E+ EG++E ++E
Sbjct: 136 -KEVRFQASLPLTRIDEEEAAAAPEAETERVEGEEEDKEE 174



 Score = 36.6 bits (83), Expect = 0.13
 Identities = 42/156 (26%), Positives = 62/156 (39%), Gaps = 13/156 (8%)

Query: 658 DSQEEAARPPAEAQAEVQSVPINNGPLLSTQPETDSEEEWNRDNSDPFHSEPKEPKQERE 717
           D Q EA +    A+A  +  P   G     QPE +   E   +  +P   EP    +E E
Sbjct: 64  DEQAEAPKGLTAAEAAGEEGPGEPGRPAEPQPEPEEPAEVGAE--EPAQPEPGAGPEELE 121

Query: 718 PEAAPESNSELASPAPEAEHSSNLTAAHPESEELIAQYDQIIKELDSGAEGLMEQNYPTP 777
            EA  E   E A+   E    ++L     + EE  A  +   + +    EG  E    T 
Sbjct: 122 AEAGAE-ELEQAAEGKEVRFQASLPLTRIDEEEAAAAPEAETERV----EGEEEDKEETQ 176

Query: 778 DPLLLTKEEEGKEESKGEKEKEGKK-----ELEDEE 808
                +KE +G E    + ++EGK+     E ED E
Sbjct: 177 RDGAESKERDG-EGRPAKSQEEGKRLYGRDEFEDLE 211


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 41.6 bits (96), Expect = 0.004
 Identities = 40/165 (24%), Positives = 69/165 (41%), Gaps = 19/165 (11%)

Query: 654 EDMKDSQEEAARPPAEAQAEVQSVPINNGPLLSTQPETDSEEEWNRDNSDPFHSEPKEPK 713
           E+ K  + +   PP +A+ E         P    + ++  EE   ++   P   E KEP 
Sbjct: 826 EEEKPQEVKVKEPPKKAEEEKAPAT----PKTEEKKDSKKEEAPKKEAPKPKVEEKKEPA 881

Query: 714 QEREPEAAPESNSELAS-----PAPEAEHSSNLTA---AHPESEELIAQYDQIIKELDSG 765
            E+  E+  E+  E A      P PE E  + +     A P+ +  +A+     KE D  
Sbjct: 882 VEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAK-----KEPDDA 936

Query: 766 AEGLMEQNYPTPDPLLLTKEEEGKEESKGEKEKEGKKELEDEEDD 810
                E + P        ++++ KEE   + E++ K E + +EDD
Sbjct: 937 KA--KEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDD 979



 Score = 40.4 bits (93), Expect = 0.009
 Identities = 43/196 (21%), Positives = 71/196 (36%), Gaps = 18/196 (9%)

Query: 652 DSEDMKDSQEEAARPPAEAQAEVQSVPINNGPLLSTQPETDSEEEWNRDNSDPFHSEPKE 711
           + E+ +  +EE   PPAE  A          P    +     E +   +   P   E K 
Sbjct: 490 EEEEAEGGEEETKSPPAEEAAS---------PEKEAKSPVKEEAKSPAEAKSPEKEEAKS 540

Query: 712 PKQEREPEAAPESNSELASPAPEAEHSSNLTAAHPESEELIAQYDQIIK-ELDSGAEGLM 770
           P + + PE A     E A   PEA+      A  P   +   +     K E  S AE   
Sbjct: 541 PAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKS 600

Query: 771 EQNYPTPDPLLLTKEEEGKEESKGEKEKEGKKELEDEEDDFDSFIAEMPAVETVPSPFVG 830
            +   +P    + +E +   E+K   ++E K   E +  +     A+ P  E   SP   
Sbjct: 601 PEKAKSP----VKEEAKSPAEAKSPVKEEAKSPAEVKSPE----KAKSPTKEEAKSPEKA 652

Query: 831 RDEAAFASRHPVRTQS 846
           +      ++ P + +S
Sbjct: 653 KSPEKEEAKSPEKAKS 668



 Score = 37.0 bits (84), Expect = 0.097
 Identities = 50/199 (25%), Positives = 73/199 (36%), Gaps = 21/199 (10%)

Query: 649 AEKDSEDMKDSQEEAARPPAEAQAEVQSVPINNGPLLSTQPETDSEEEWNRDNSDPFHSE 708
           A+  +E     +EEA  P     AEV+S      P    + E  S  E       P   E
Sbjct: 524 AKSPAEAKSPEKEEAKSP-----AEVKSPEKAKSP---AKEEAKSPPE----AKSPEKEE 571

Query: 709 PKEPKQEREPEAAPESNSELASPAPEAEHSSNLTAAHPESEELIAQYDQIIK-ELDSGAE 767
            K P + + PE A     E A    EA+      +   E  +  A+    +K E  S AE
Sbjct: 572 AKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAE 631

Query: 768 GLMEQNYPTPDPLLLTKEEEGKEESKGEKEKEGKKELEDEEDDFDSFIAEMPAVETVPSP 827
               +   +P     TKEE    E     EKE  K  E  +       AE  + E   SP
Sbjct: 632 VKSPEKAKSP-----TKEEAKSPEKAKSPEKEEAKSPEKAKSPVK---AEAKSPEKAKSP 683

Query: 828 FVGRDEAAFASRHPVRTQS 846
                ++   ++ PV+ ++
Sbjct: 684 VKAEAKSPEKAKSPVKEEA 702



 Score = 35.8 bits (81), Expect = 0.22
 Identities = 38/187 (20%), Positives = 71/187 (37%), Gaps = 29/187 (15%)

Query: 660 QEEAARPPAEAQAEVQSVPINNGPLLSTQPETDSEEEWNRDNSDPFHSEPKEPKQEREPE 719
           ++E  + P + + + Q V +        +P   +EEE            P  PK E + +
Sbjct: 816 KKEEVKSPVKEEEKPQEVKVK-------EPPKKAEEE----------KAPATPKTEEKKD 858

Query: 720 AAPESNSELASPAPEAEHSSNLTAAHPESEELIAQYDQIIKELDSGAEGLMEQNYPTPDP 779
           +  E   +  +P P+ E         P+  ++ A+ +          E   ++  PTP+ 
Sbjct: 859 SKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKE----------EAEDKKKVPTPEK 908

Query: 780 LLLTKEEEGKEESKGEKEKEGKKELEDEEDDFDSFIAEMPAVETVPSPFVGRDEAAFASR 839
               K E  ++    EK +  KKE +D +    S  AE    E  P     ++E A    
Sbjct: 909 EAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKK--EAAPEKKDTKEEKAKKPE 966

Query: 840 HPVRTQS 846
              +T++
Sbjct: 967 EKPKTEA 973



 Score = 30.4 bits (67), Expect = 9.1
 Identities = 22/68 (32%), Positives = 29/68 (42%), Gaps = 5/68 (7%)

Query: 784 KEEEGKEESKGEKE-----KEGKKELEDEEDDFDSFIAEMPAVETVPSPFVGRDEAAFAS 838
           KEEEGKEE  GE+E     +E  K    EE       A+ P  E   SP   +      +
Sbjct: 479 KEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEA 538

Query: 839 RHPVRTQS 846
           + P   +S
Sbjct: 539 KSPAEVKS 546


>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
           sapiens]
          Length = 1152

 Score = 41.6 bits (96), Expect = 0.004
 Identities = 42/170 (24%), Positives = 71/170 (41%), Gaps = 8/170 (4%)

Query: 649 AEKDSEDMKDSQEEAARPPAEAQAEVQSVPINNGPLLS----TQPETDSEEEWNRDNSDP 704
           AEK+    +D +E+  +   +   + ++  +  G         + E D EEE  ++    
Sbjct: 697 AEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGK 756

Query: 705 FHSEPKEPKQEREPEAAPESNSELASPAPEAEHSSNLTAAHPESEELIAQYDQIIKELDS 764
              E +E + ERE E       E A    + E   +      E  E   +  +   E++ 
Sbjct: 757 EEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEG 816

Query: 765 G--AEGLMEQNYPTPDPLLLTKEEEG-KEESKGEKEK-EGKKELEDEEDD 810
           G   EG  E+     +     +E EG +EE +GE+E+ EGK E E EE +
Sbjct: 817 GEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGE 866



 Score = 36.6 bits (83), Expect = 0.13
 Identities = 47/186 (25%), Positives = 76/186 (40%), Gaps = 25/186 (13%)

Query: 629 KGSYIEESDFQ---DDVMVYRLCAEKD---SEDMKDSQEEAARPPAEAQAEVQSVPINNG 682
           KG+ IEE + +   ++V V+    EK    S+D+ D + E +   A++  E +  P   G
Sbjct: 597 KGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTD-KAEVSEGKAKSVGEAEDGPEGRG 655

Query: 683 PLLSTQPETDSEEEWNRDNSDPFHSEPKEPKQEREPEAAPESNSELASPAPEAEHSSNLT 742
              + +  +   E W     D    + ++ K   E E   E   ELA    + E      
Sbjct: 656 DG-TCEEGSSGAEHWQ----DEEREKGEKDKGRGEMERPGEGEKELAE---KEEWKKRDG 707

Query: 743 AAHPESEELIAQYDQIIKELDSGAEGLMEQNYPTPDPLLLTKEEEGKEESKGEKEKEGKK 802
               + E       +  +E++ G E    +           +EEEG  E + EKE EGK+
Sbjct: 708 EEQEQKEREQGHQKERNQEMEEGGEEEHGEG----------EEEEGDREEEEEKEGEGKE 757

Query: 803 ELEDEE 808
           E E EE
Sbjct: 758 EGEGEE 763



 Score = 33.9 bits (76), Expect = 0.82
 Identities = 38/164 (23%), Positives = 64/164 (39%), Gaps = 15/164 (9%)

Query: 650 EKDSEDMKDSQEEAARPPAEAQAEVQSVPINNGPLLSTQPETDSEEEWNRDNSDPFHSEP 709
           E++ E+ +  +EE A    + + E              + ET+   E   +  +    E 
Sbjct: 767 EREKEEGERKKEERAGKEEKGEEEGDQGE-------GEEEETEGRGEEKEEGGEVEGGEV 819

Query: 710 KEPKQEREPEAAPESNSELASPAPEAEHSSNLTAAHPESEELIAQYDQIIKELDSGAEGL 769
           +E K ERE E       E      E E          + EE   + +   +  +   EG 
Sbjct: 820 EEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGE 879

Query: 770 MEQNYPTPDPLLLTKEEEGK---EESKGEKEKEGKKELEDEEDD 810
            E+     +     +E EG+   EE +GE E+EG+ E E+EE +
Sbjct: 880 EEEGEGEGE-----EEGEGEGEEEEGEGEGEEEGEGEGEEEEGE 918



 Score = 33.9 bits (76), Expect = 0.82
 Identities = 38/161 (23%), Positives = 58/161 (36%), Gaps = 14/161 (8%)

Query: 650  EKDSEDMKDSQEEAARPPAEAQAEVQSVPINNGPLLSTQPETDSEEEWNRDNSDPFHSEP 709
            E+  E   + +EE      E + E +            + E + EEE      +    E 
Sbjct: 869  EEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEG 928

Query: 710  KEPKQEREPEAAPESNS---ELASPAPEAEHSSNLTAAHPESEELIAQYDQIIKELDSGA 766
            +   +E E E   E      E      E E          E E    + +   +E +   
Sbjct: 929  EGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEG 988

Query: 767  EGLMEQNYPTPDPLLLTKEEEGKEESKGEKEKEGKKELEDE 807
            EG  E+            EEEG+EE +GE+E EG+ E E+E
Sbjct: 989  EGEEEEG-----------EEEGEEEGEGEEEGEGEGEEEEE 1018



 Score = 33.1 bits (74), Expect = 1.4
 Identities = 37/163 (22%), Positives = 60/163 (36%), Gaps = 2/163 (1%)

Query: 650 EKDSEDMKDSQEEAARPPAEAQAEVQSVPINNGPLLSTQPETDSEEEWNRDNSDPFHSEP 709
           EK  E+    + E        + + +   +  G +   + E + EEE      +    E 
Sbjct: 785 EKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEE 844

Query: 710 KEPK-QEREPEAAPESNSELASPAPEAEHSSNLTAAHPESEELIAQYDQIIKELDSGAEG 768
           +E + +E E E   E   E      E E             E   + +   +E +   EG
Sbjct: 845 EEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEG 904

Query: 769 LMEQNYPTPDPLLLTKEEEGKEESKGE-KEKEGKKELEDEEDD 810
             E      +     K EE  EE +GE +E+EG+ E ED E +
Sbjct: 905 EEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGE 947



 Score = 30.4 bits (67), Expect = 9.1
 Identities = 39/167 (23%), Positives = 63/167 (37%), Gaps = 10/167 (5%)

Query: 650  EKDSEDMKDSQEEAARPPAEAQAEVQSVPINNGPLLSTQPETDSEEEWNRDNSDPFHSEP 709
            E + E   + +EE      E + E        G     + E +  E    +    +  E 
Sbjct: 903  EGEEEGEGEGEEEEGEGKGEEEGEEGE---GEGEEEEGEGEGEDGEGEGEEEEGEWEGEE 959

Query: 710  KEPKQEREPEAAPESNS-ELASPAPEAEHSSNLTAAHPESEELIAQYDQIIKELDSGAEG 768
            +E + E E E   E    E      E E          E EE     ++   E +   EG
Sbjct: 960  EEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEG 1019

Query: 769  LMEQNYPTPDPLLLTKEEEGKEESKGEKEKEG-----KKELEDEEDD 810
             +E      +     +EEEG+EE + E+EKEG     ++  E+EE++
Sbjct: 1020 EVEGEVEGEEGEGEGEEEEGEEEGE-EREKEGEGEENRRNREEEEEE 1065


>gi|158631177 homeodomain leucine zipper protein [Homo sapiens]
          Length = 550

 Score = 41.2 bits (95), Expect = 0.005
 Identities = 33/133 (24%), Positives = 56/133 (42%), Gaps = 11/133 (8%)

Query: 696 EWNRDNSDPFHSEPKEPKQEREPEAAPESNSE-------LASPAPEAEHSSNLTAAHPES 748
           +W RDN+ P     ++P     P +    N         +  P P+ +      AAH + 
Sbjct: 417 KWFRDNAVPGAPSFQDPAIPTPPPSTRSLNERAETPPLPIPPPPPDIQPLERYWAAHQQL 476

Query: 749 EEL-IAQYDQIIKELDSGAEGLMEQNYPTPDPLLLT---KEEEGKEESKGEKEKEGKKEL 804
            E  I Q  Q  +          +   P P  +++    +EEE +EE   + E+E ++E 
Sbjct: 477 RETDIPQLSQASRLSTQQVLDWFDSRLPQPAEVVVCLDEEEEEEEEELPEDDEEEEEEEE 536

Query: 805 EDEEDDFDSFIAE 817
           ED++DD D  I +
Sbjct: 537 EDDDDDDDDVIIQ 549


>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
          Length = 953

 Score = 40.4 bits (93), Expect = 0.009
 Identities = 47/184 (25%), Positives = 74/184 (40%), Gaps = 34/184 (18%)

Query: 630 GSYIEESDFQDDVMVYRLCAEKDSEDMKDSQEEAARPPAEAQAEVQSVPINNGPLLSTQP 689
           G+ +  SD +D+    R  ++++ ED    +E+ A  P     + +   ++ GP      
Sbjct: 40  GAGVRASDLEDEESAARGPSQEE-EDNHSDEEDRASEPKSQDQDSEVNELSRGP------ 92

Query: 690 ETDSEEEWNRDNSDPFHSEPKEPKQEREPEAAPESNSELASPAPEAEHSSNLTAAHPESE 749
                       S P   E  E +++R  +   E++S         EH  +     PE  
Sbjct: 93  -----------TSSPCEEEGDEGEEDRTSDLRDEASSVTRE---LDEHELDYDEEVPEEP 138

Query: 750 ELIAQYDQIIKELDSGAEGLMEQNYPTPDPLLLTKEEEGKE--ESKGEKEK-EGKKELED 806
               Q D+  K   +GAE   E+   TP        EEGK   +S GEKE  E  KE + 
Sbjct: 139 APAVQEDEAEK---AGAEDDEEKGEGTP-------REEGKAGVQSVGEKESLEAAKEKKK 188

Query: 807 EEDD 810
           E+DD
Sbjct: 189 EDDD 192



 Score = 31.6 bits (70), Expect = 4.1
 Identities = 32/119 (26%), Positives = 49/119 (41%), Gaps = 20/119 (16%)

Query: 720 AAPESNSELASPAPEAEHSSNLTAAHPESEELIAQ-YDQIIKELDSGAEGLMEQNYPTPD 778
           A+   + E A+  P  E   N +     + E  +Q  D  + EL  G         PT  
Sbjct: 45  ASDLEDEESAARGPSQEEEDNHSDEEDRASEPKSQDQDSEVNELSRG---------PTSS 95

Query: 779 PLLLTKEEEGKEESKGEKEKEGK---KELEDEEDDFDSFIAEMPAVETVPSPFVGRDEA 834
           P    + +EG+E+   +   E     +EL++ E D+D  + E PA      P V  DEA
Sbjct: 96  PCE-EEGDEGEEDRTSDLRDEASSVTRELDEHELDYDEEVPEEPA------PAVQEDEA 147


>gi|157738619 smoothelin-like 1 [Homo sapiens]
          Length = 512

 Score = 40.4 bits (93), Expect = 0.009
 Identities = 52/224 (23%), Positives = 98/224 (43%), Gaps = 14/224 (6%)

Query: 600 DDLEVSGPPAPIDPPKHIQEMKKNALLLFKGSYIEESDFQDDVMVYRLCAEKDSEDMK-D 658
           D+ E+SG  AP +  K       N     +    E++  +D +           +++K +
Sbjct: 38  DNPEMSGGGAPAEETKGTAGKAINEGPPTESGKQEKAPAEDGMSAELQGEANGLDEVKVE 97

Query: 659 SQEEAA-RPPAEAQ-----AEVQSVPINNGPLLSTQPETDSEEEWNRDNSDPFHSEP-KE 711
           SQ EA  +  AEA+      E +   + +  +   + ET SE +   +      SE  K 
Sbjct: 98  SQREAGGKEDAEAELKKEDGEKEETTVGSQEMTGRKEETKSEPKEAEEKESTLASEKQKA 157

Query: 712 PKQEREPEAAPESNS-ELASPAPEA--EHSSNLTAAHPES-EELIAQYDQIIKELDSGAE 767
            ++E +PE+  ++++ +   P P+A  E     TA+  E+ +      +   K  D  A+
Sbjct: 158 EEKEAKPESGQKADANDRDKPEPKATVEEEDAKTASQEETGQRKECSTEPKEKATDEEAK 217

Query: 768 GLMEQNYPTPDPLLLTKEEEGKEESK--GEKEKEGKKELEDEED 809
              ++     +     KE +GKEE+K   ++E + K+E ED E+
Sbjct: 218 AESQKAVVEDEAKAEPKEPDGKEEAKHGAKEEADAKEEAEDAEE 261



 Score = 33.9 bits (76), Expect = 0.82
 Identities = 33/161 (20%), Positives = 66/161 (40%), Gaps = 11/161 (6%)

Query: 653 SEDMKDSQEEAARPPAEAQAEVQSVPINNGPLLSTQPETDSEEEWNRDNSDPFHSEPKEP 712
           S++M   +EE    P EA+ +  ++        + + E   E     D +D    EPK  
Sbjct: 126 SQEMTGRKEETKSEPKEAEEKESTLASEKQK--AEEKEAKPESGQKADANDRDKPEPKAT 183

Query: 713 KQEREPE-AAPESNSELASPAPEAEHSSNLTAAHPESEELIAQYDQIIKELDSGAEGLME 771
            +E + + A+ E   +    + E +  +    A  ES++ + + +   K      +G  E
Sbjct: 184 VEEEDAKTASQEETGQRKECSTEPKEKATDEEAKAESQKAVVEDEA--KAEPKEPDGKEE 241

Query: 772 QNYPTPDPLLLTKEEEGKEESKGEKEKEGKKELEDEEDDFD 812
             +   +      E + KEE++  +E E     E++E D +
Sbjct: 242 AKHGAKE------EADAKEEAEDAEEAEPGSPSEEQEQDVE 276



 Score = 30.8 bits (68), Expect = 6.9
 Identities = 36/153 (23%), Positives = 53/153 (34%), Gaps = 9/153 (5%)

Query: 614 PKHIQEMKKNALLLFKGSYIEESDFQDDVMVYRLCAEKDSEDMKDSQEEAARPPAEAQAE 673
           PK  +E  K + L  +    EE + + +        ++D  + K + EE     A  +  
Sbjct: 140 PKEAEE--KESTLASEKQKAEEKEAKPESGQKADANDRDKPEPKATVEEEDAKTASQEET 197

Query: 674 VQSVPINNGPLLSTQPETDSEEEWNRDNSDPFHSEPKEPKQEREPEAAPESNSELASPAP 733
            Q    +  P      E    E       D   +EPKEP  + E   A     E A    
Sbjct: 198 GQRKECSTEPKEKATDEEAKAESQKAVVEDEAKAEPKEPDGKEE---AKHGAKEEADAKE 254

Query: 734 EAEHSSNLTAAHPESEELIAQYDQIIKELDSGA 766
           EAE +       P  E    Q   + KE + GA
Sbjct: 255 EAEDAEEAEPGSPSEE----QEQDVEKEPEGGA 283


>gi|21735415 centromere protein B [Homo sapiens]
          Length = 599

 Score = 40.0 bits (92), Expect = 0.011
 Identities = 60/281 (21%), Positives = 108/281 (38%), Gaps = 39/281 (13%)

Query: 613 PPKHIQEMKKNALLLFKGSYIEESDFQDDVMVYRLCAEKDSEDMKDSQ---EEA------ 663
           PP  +  +++  +   KG Y +        M+ +  A  + +D    Q    EA      
Sbjct: 318 PPGTVHPLERGVVQQVKGHYRQ-------AMLLKAMAALEGQDPSGLQLGLTEALHFVAA 370

Query: 664 ---ARPPAEAQAEVQSVPINNGP---LLSTQPETDSEEEWNRDNSDPFHSEPKEPKQERE 717
              A  P++  A  +      GP   + ++      EEE   +  +    E +E ++E E
Sbjct: 371 AWQAVEPSDIAACFREAGFGGGPNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGE 430

Query: 718 PEAAPESNSELASPAPEAEHSSNLTAAHPESEELIAQYDQIIKELDSGAEGLMEQN---- 773
            E       E      E E   ++ +   E E+  +  + +  E +  A+G++E      
Sbjct: 431 EEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGL--EAEDWAQGVVEAGGSFG 488

Query: 774 -YPTPDPLLLTKEE--EGKEESKGEKEKEGKKELEDEEDDFDSFIAEMPAVETVPSPFVG 830
            Y   +          EG E+S  + E+E  +E +DE++D D    +    + VP P  G
Sbjct: 489 AYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDD---DEEDGDEVPVPSFG 545

Query: 831 RDEAAFASRHPVRTQSTPFTGPFISVVLSKLENMLENSLHV 871
              A FA    V+   T F  P    V S + ++  + +HV
Sbjct: 546 EAMAYFAM---VKRYLTSF--PIDDRVQSHILHLEHDLVHV 581


>gi|48255877 troponin T type 2, cardiac isoform 1 [Homo sapiens]
          Length = 295

 Score = 40.0 bits (92), Expect = 0.011
 Identities = 43/173 (24%), Positives = 67/173 (38%), Gaps = 30/173 (17%)

Query: 650 EKDSEDMKDSQEEAARPPAEAQAEVQSVPINNGPLLSTQPETDSEEEWNRDNSDPFHSEP 709
           E+D  + +D QEEAA   AEA+AE +           T+ E D EEE  ++  D    E 
Sbjct: 24  EEDWREDEDEQEEAAEEDAEAEAETE----------ETRAEEDEEEEEAKEAEDGPMEES 73

Query: 710 KEPKQEREPEAAPE----------SNSELASPAPEAEHSSNLTAAH-----PESEELIAQ 754
           K   +   P   P            +        +      L  AH      E EEL++ 
Sbjct: 74  KPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSL 133

Query: 755 YDQIIKELDSGAEGLMEQNYPTPDPLLLTKEEEGKEESKGEKEKEGKKELEDE 807
            D+I +     AE    +N    +     ++    EE    +E+E +++ EDE
Sbjct: 134 KDRIERRRAERAEQQRIRNEREKE-----RQNRLAEERARREEEENRRKAEDE 181



 Score = 33.9 bits (76), Expect = 0.82
 Identities = 21/69 (30%), Positives = 35/69 (50%), Gaps = 1/69 (1%)

Query: 710 KEPKQEREPEAAPESNSELASPAPEAEHSSNLTA-AHPESEELIAQYDQIIKELDSGAEG 768
           +E ++E + EAA E   +      E E ++   A A  E+EE  A+ D+  +E     +G
Sbjct: 9   EEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDG 68

Query: 769 LMEQNYPTP 777
            ME++ P P
Sbjct: 69  PMEESKPKP 77


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.392 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,794,310
Number of Sequences: 37866
Number of extensions: 2151654
Number of successful extensions: 16286
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 87
Number of HSP's successfully gapped in prelim test: 427
Number of HSP's that attempted gapping in prelim test: 12827
Number of HSP's gapped (non-prelim): 2635
length of query: 1040
length of database: 18,247,518
effective HSP length: 112
effective length of query: 928
effective length of database: 14,006,526
effective search space: 12998056128
effective search space used: 12998056128
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.