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Search of human proteins with 157743245
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|157743245 WD repeat domain 43 [Homo sapiens]
(677 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|157743245 WD repeat domain 43 [Homo sapiens] 1375 0.0
gi|83779014 katanin p80 subunit B 1 [Homo sapiens] 66 1e-10
gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens] 65 3e-10
gi|23199987 WD repeat domain 5B [Homo sapiens] 63 1e-09
gi|21361639 DIPB protein [Homo sapiens] 62 2e-09
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 59 1e-08
gi|17975763 myelin transcription factor 1 [Homo sapiens] 58 3e-08
gi|109948304 smu-1 suppressor of mec-8 and unc-52 homolog [Homo ... 58 3e-08
gi|239756368 PREDICTED: similar to acidic (leucine-rich) nuclear... 58 3e-08
gi|239750893 PREDICTED: similar to acidic (leucine-rich) nuclear... 58 3e-08
gi|4557741 platelet-activating factor acetylhydrolase, isoform I... 57 4e-08
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 57 6e-08
gi|60498973 myelin transcription factor 1-like [Homo sapiens] 57 6e-08
gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 famil... 57 7e-08
gi|16554629 WD repeat domain 5 [Homo sapiens] 56 1e-07
gi|16554627 WD repeat domain 5 [Homo sapiens] 56 1e-07
gi|21735415 centromere protein B [Homo sapiens] 56 1e-07
gi|115529449 upstream binding transcription factor, RNA polymera... 56 1e-07
gi|115529451 upstream binding transcription factor, RNA polymera... 56 1e-07
gi|7657671 upstream binding transcription factor, RNA polymerase... 56 1e-07
gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens] 55 2e-07
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 55 3e-07
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 55 3e-07
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 55 3e-07
gi|169210053 PREDICTED: hypothetical protein [Homo sapiens] 54 4e-07
gi|4759276 RNA, U3 small nucleolar interacting protein 2 [Homo s... 54 5e-07
gi|21071067 TBP-associated factor 5 [Homo sapiens] 54 5e-07
gi|5803221 WD repeat-containing protein 3 [Homo sapiens] 53 8e-07
gi|55956788 nucleolin [Homo sapiens] 53 1e-06
gi|156071450 nardilysin isoform a [Homo sapiens] 52 1e-06
>gi|157743245 WD repeat domain 43 [Homo sapiens]
Length = 677
Score = 1375 bits (3558), Expect = 0.0
Identities = 677/677 (100%), Positives = 677/677 (100%)
Query: 1 MAAGGGGSCDPLAPAGVPCAFSPHSQAYFALASTDGHLRVWETANNRLHQEYVPSAHLSG 60
MAAGGGGSCDPLAPAGVPCAFSPHSQAYFALASTDGHLRVWETANNRLHQEYVPSAHLSG
Sbjct: 1 MAAGGGGSCDPLAPAGVPCAFSPHSQAYFALASTDGHLRVWETANNRLHQEYVPSAHLSG 60
Query: 61 TCTCLAWAPARLQAKESPQRKKRKSEAVGMSNQTDLLALGTAVGSILLYSTVKGELHSKL 120
TCTCLAWAPARLQAKESPQRKKRKSEAVGMSNQTDLLALGTAVGSILLYSTVKGELHSKL
Sbjct: 61 TCTCLAWAPARLQAKESPQRKKRKSEAVGMSNQTDLLALGTAVGSILLYSTVKGELHSKL 120
Query: 121 ISGGHDNRVNCIQWHQDSGCLYSCSDDKHIVEWNVQTCKVKCKWKGDNSSVSSLCISPDG 180
ISGGHDNRVNCIQWHQDSGCLYSCSDDKHIVEWNVQTCKVKCKWKGDNSSVSSLCISPDG
Sbjct: 121 ISGGHDNRVNCIQWHQDSGCLYSCSDDKHIVEWNVQTCKVKCKWKGDNSSVSSLCISPDG 180
Query: 181 KMLLSAGRTIKLWVLETKEVYRHFTGHATPVSSLMFTTIRPPNESQPFDGITGLYFLSGA 240
KMLLSAGRTIKLWVLETKEVYRHFTGHATPVSSLMFTTIRPPNESQPFDGITGLYFLSGA
Sbjct: 181 KMLLSAGRTIKLWVLETKEVYRHFTGHATPVSSLMFTTIRPPNESQPFDGITGLYFLSGA 240
Query: 241 VHDRLLNVWQVRSENKEKSAVMSFTVTDEPVYIDLTLSENKEEPVKLAVVCRDGQVHLFE 300
VHDRLLNVWQVRSENKEKSAVMSFTVTDEPVYIDLTLSENKEEPVKLAVVCRDGQVHLFE
Sbjct: 241 VHDRLLNVWQVRSENKEKSAVMSFTVTDEPVYIDLTLSENKEEPVKLAVVCRDGQVHLFE 300
Query: 301 HILNGYCKKPLTSNCTIQIATPGKGKKSTPKPIPILAAGFCSDKMSLLLVYGSWFQPTIE 360
HILNGYCKKPLTSNCTIQIATPGKGKKSTPKPIPILAAGFCSDKMSLLLVYGSWFQPTIE
Sbjct: 301 HILNGYCKKPLTSNCTIQIATPGKGKKSTPKPIPILAAGFCSDKMSLLLVYGSWFQPTIE 360
Query: 361 RVALNSREPHMCLVRDISNCWAPKVETAITKVRTPVMNSEAKVLVPGIPGHHAAIKPAPP 420
RVALNSREPHMCLVRDISNCWAPKVETAITKVRTPVMNSEAKVLVPGIPGHHAAIKPAPP
Sbjct: 361 RVALNSREPHMCLVRDISNCWAPKVETAITKVRTPVMNSEAKVLVPGIPGHHAAIKPAPP 420
Query: 421 QTEQVESKRKSGGNEVSIEERLGAMDIDTHKKGKEDLQTNSFPVLLTQGLESNDFEMLNK 480
QTEQVESKRKSGGNEVSIEERLGAMDIDTHKKGKEDLQTNSFPVLLTQGLESNDFEMLNK
Sbjct: 421 QTEQVESKRKSGGNEVSIEERLGAMDIDTHKKGKEDLQTNSFPVLLTQGLESNDFEMLNK 480
Query: 481 VLQTRNVNLIKKTVLRMPLHTIIPLLQELTKRLQGHPNSAVLMVQWLKCVLTVHASYLST 540
VLQTRNVNLIKKTVLRMPLHTIIPLLQELTKRLQGHPNSAVLMVQWLKCVLTVHASYLST
Sbjct: 481 VLQTRNVNLIKKTVLRMPLHTIIPLLQELTKRLQGHPNSAVLMVQWLKCVLTVHASYLST 540
Query: 541 LPDLVPQLGTLYQLMESRVKTFQKLSHLHGKLILLITQVTASEKTKGATSPGQKAKLVYE 600
LPDLVPQLGTLYQLMESRVKTFQKLSHLHGKLILLITQVTASEKTKGATSPGQKAKLVYE
Sbjct: 541 LPDLVPQLGTLYQLMESRVKTFQKLSHLHGKLILLITQVTASEKTKGATSPGQKAKLVYE 600
Query: 601 EESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDEDAEGKDEENGEDRDTASEK 660
EESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDEDAEGKDEENGEDRDTASEK
Sbjct: 601 EESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDEDAEGKDEENGEDRDTASEK 660
Query: 661 ELNGDSDLDPENESEEE 677
ELNGDSDLDPENESEEE
Sbjct: 661 ELNGDSDLDPENESEEE 677
>gi|83779014 katanin p80 subunit B 1 [Homo sapiens]
Length = 655
Score = 65.9 bits (159), Expect = 1e-10
Identities = 46/168 (27%), Positives = 78/168 (46%), Gaps = 18/168 (10%)
Query: 86 EAVGMSNQTDLLALGTAVGSILLYSTVKGELHSKLISGGHDNRVNCIQWHQDSGCLYSCS 145
E+V ++ +L+ G+ GSI ++ ++ L+ GH + + +H + S S
Sbjct: 67 ESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLM--GHKANICSLDFHPYGEFVASGS 124
Query: 146 DDKHIVEWNVQTCKVKCKWKGDNSSVSSLCISPDGKMLLSAG--RTIKLWVLETKEVYRH 203
D +I W+++ +++G + +V L SPDGK L SA T+KLW L ++
Sbjct: 125 QDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSE 184
Query: 204 FTGHATPVSSLMFTTIRPPNESQPFDGITGLYFLSGAVHDRLLNVWQV 251
F GH PV+ + F PNE Y L+ DR + W +
Sbjct: 185 FPGHTGPVNVVEF----HPNE----------YLLASGSSDRTIRFWDL 218
Score = 49.3 bits (116), Expect = 1e-05
Identities = 28/95 (29%), Positives = 46/95 (48%), Gaps = 2/95 (2%)
Query: 124 GHDNRVNCIQWHQDSGCLYSCSDDKHIVEWNVQTCKVKCKWKGDNSSVSSLCISPDGKML 183
GH V C+++ D L S +DD + W++ K+ ++ G V+ + P+ +L
Sbjct: 145 GHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLL 204
Query: 184 LSAG--RTIKLWVLETKEVYRHFTGHATPVSSLMF 216
S RTI+ W LE +V G PV S++F
Sbjct: 205 ASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLF 239
Score = 41.2 bits (95), Expect = 0.003
Identities = 41/178 (23%), Positives = 70/178 (39%), Gaps = 28/178 (15%)
Query: 86 EAVGMSNQTDLLALGTAVGSIL----------LYSTVKGELHSKLISGGHDNRVNCIQWH 135
E V ++ L LG A G +L L+S K L GH + V ++ +
Sbjct: 15 EIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLT--GHTSPVESVRLN 72
Query: 136 QDSGCLYSCSDDKHIVEWNVQTCKVKCKWKGDNSSVSSLCISPDGKMLLSAGR--TIKLW 193
+ + S I W+++ K+ G +++ SL P G+ + S + IKLW
Sbjct: 73 TPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLW 132
Query: 194 VLETKEVYRHFTGHATPVSSLMFTTIRPPNESQPFDGITGLYFLSGAVHDRLLNVWQV 251
+ K + GH+ V L F+ DG +L+ A D + +W +
Sbjct: 133 DIRRKGCVFRYRGHSQAVRCLRFSP----------DG----KWLASAADDHTVKLWDL 176
Score = 38.5 bits (88), Expect = 0.021
Identities = 23/81 (28%), Positives = 42/81 (51%), Gaps = 2/81 (2%)
Query: 105 SILLYSTVKGELHSKLISGGHDNRVNCIQWHQDSGCLYSCSDDKHIVEWNVQTCKVKCKW 164
++ L+ G++ S+ GH VN +++H + L S S D+ I W+++ +V
Sbjct: 170 TVKLWDLTAGKMMSEF--PGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCI 227
Query: 165 KGDNSSVSSLCISPDGKMLLS 185
+G+ V S+ +PDG L S
Sbjct: 228 EGEPGPVRSVLFNPDGCCLYS 248
>gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens]
Length = 589
Score = 64.7 bits (156), Expect = 3e-10
Identities = 42/135 (31%), Positives = 66/135 (48%), Gaps = 16/135 (11%)
Query: 121 ISGGHDNRVNCIQWHQDSGCLYSCSDDKHIVEWNVQTCKVKCKWKGDNSSVSSLCISPDG 180
I GH V+C+++H +S L + S DK + W+ Q + G V SL SP+G
Sbjct: 421 IYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNG 480
Query: 181 KMLLSAG--RTIKLWVLETKEVYRHFTGHATPVSSLMFTTIRPPNESQPFDGITGLYFLS 238
K L SAG + +KLW L + +Y+ GH ++SL F+ P G+ ++
Sbjct: 481 KYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSLTFS---------PDSGL-----IA 526
Query: 239 GAVHDRLLNVWQVRS 253
A D + VW +R+
Sbjct: 527 SASMDNSVRVWDIRN 541
Score = 43.5 bits (101), Expect = 6e-04
Identities = 55/207 (26%), Positives = 84/207 (40%), Gaps = 28/207 (13%)
Query: 124 GHDNRVNCIQWHQDSGCLYSCSDDKHIVEWNVQTCKVKCKWKGDNSSVSSLCISPDGKML 183
GH V ++ DS L SCS+D I W++ + ++G V L ISP
Sbjct: 340 GHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPYSLYF 399
Query: 184 LSAG--RTIKLWVLETKEVYRHFTGHATPVSSLMFTTIRPPNESQPFDGITGLYFLSGAV 241
S RT +LW + R + GH V + F PN + Y +G+
Sbjct: 400 ASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKF----HPNSN---------YLATGST 446
Query: 242 HDRLLNVWQVRSENKEKSAVMSFTVTDEPVYIDLTLSENKEEPVKLAVVCRDGQVHLFEH 301
D+ + +W + N +V FT PV + L S N + LA D ++ L++
Sbjct: 447 -DKTVRLWSAQQGN----SVRLFTGHRGPV-LSLAFSPNGK---YLASAGEDQRLKLWD- 496
Query: 302 ILNGYCKKPL---TSNCTIQIATPGKG 325
+ +G K L T N T +P G
Sbjct: 497 LASGTLYKELRGHTDNITSLTFSPDSG 523
Score = 41.2 bits (95), Expect = 0.003
Identities = 44/208 (21%), Positives = 89/208 (42%), Gaps = 42/208 (20%)
Query: 22 SPHSQAYFALASTDGHLRVWETANNRLHQEYVPSAHLSGTCTCLAWAPARLQAKESPQRK 81
SP+S YFA S D R+W +R + + + HL+ C+ + P
Sbjct: 393 SPYS-LYFASGSHDRTARLWSF--DRTYPLRIYAGHLADV-DCVKFHP------------ 436
Query: 82 KRKSEAVGMSNQTDLLALGTAVGSILLYSTVKGELHSKLISGGHDNRVNCIQWHQDSGCL 141
++ LA G+ ++ L+S +G +S + GH V + + + L
Sbjct: 437 -----------NSNYLATGSTDKTVRLWSAQQG--NSVRLFTGHRGPVLSLAFSPNGKYL 483
Query: 142 YSCSDDKHIVEWNVQTCKVKCKWKGDNSSVSSLCISPDGKMLLSAG--RTIKLWVL---- 195
S +D+ + W++ + + + +G +++SL SPD ++ SA ++++W +
Sbjct: 484 ASAGEDQRLKLWDLASGTLYKELRGHTDNITSLTFSPDSGLIASASMDNSVRVWDIRNTY 543
Query: 196 -------ETKEVYRHFTGHATPVSSLMF 216
+ E+ +TG + V S+ F
Sbjct: 544 CSAPADGSSSELVGVYTGQMSNVLSVQF 571
Score = 32.0 bits (71), Expect = 1.9
Identities = 36/157 (22%), Positives = 60/157 (38%), Gaps = 32/157 (20%)
Query: 15 AGVPCA-FSPHSQAYFALASTDGHLRVWETANNRLHQEYVPSAHLSGTCTCLAWAPARLQ 73
A V C F P+S Y A STD +R+W + + + H G LA++P
Sbjct: 427 ADVDCVKFHPNSN-YLATGSTDKTVRLWSAQQGNSVRLF--TGH-RGPVLSLAFSPNGKY 482
Query: 74 AKESPQRKKRKSEAVGMSNQTDLLALGTAVGSILLYSTVKGELHSKLISGGHDNRVNCIQ 133
+ + ++ K L+ G L+ +L GH + + +
Sbjct: 483 LASAGEDQRLK-----------------------LWDLASGTLYKEL--RGHTDNITSLT 517
Query: 134 WHQDSGCLYSCSDDKHIVEWNVQTCKVKCKWKGDNSS 170
+ DSG + S S D + W+++ C D SS
Sbjct: 518 FSPDSGLIASASMDNSVRVWDIR--NTYCSAPADGSS 552
>gi|23199987 WD repeat domain 5B [Homo sapiens]
Length = 330
Score = 62.8 bits (151), Expect = 1e-09
Identities = 45/177 (25%), Positives = 82/177 (46%), Gaps = 18/177 (10%)
Query: 87 AVGMSNQTDLLALGTAVGSILLYSTVKGELHSKLISGGHDNRVNCIQWHQDSGCLYSCSD 146
+V S + LA +A I+++ G+ L GH+ ++ + W DS L S SD
Sbjct: 46 SVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLY--GHNLEISDVAWSSDSSRLVSASD 103
Query: 147 DKHIVEWNVQTCKVKCKWKGDNSSVSSLCISPDGKMLLSAG--RTIKLWVLETKEVYRHF 204
DK + W+V++ K KG ++ V +P +++S T+K+W ++T + +
Sbjct: 104 DKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVKTGKCLKTL 163
Query: 205 TGHATPVSSLMFTTIRPPNESQPFDGITGLYFLSGAVHDRLLNVWQVRSENKEKSAV 261
+ H+ PVS++ F +G +SG+ +D L +W S K+ V
Sbjct: 164 SAHSDPVSAVHF-------------NCSGSLIVSGS-YDGLCRIWDAASGQCLKTLV 206
Score = 45.1 bits (105), Expect = 2e-04
Identities = 33/132 (25%), Positives = 59/132 (44%), Gaps = 16/132 (12%)
Query: 124 GHDNRVNCIQWHQDSGCLYSCSDDKHIVEWNVQTCKVKCKWKGDNSSVSSLCISPDGKML 183
GH V+ +++ + L S S D+ I+ W K + G N +S + S D L
Sbjct: 39 GHTEAVSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSSRL 98
Query: 184 LSAG--RTIKLWVLETKEVYRHFTGHATPVSSLMFTTIRPPNESQPFDGITGLYFLSGAV 241
+SA +T+KLW + + + + GH+ V F PP+ +SG+
Sbjct: 99 VSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNF---NPPSN----------LIISGS- 144
Query: 242 HDRLLNVWQVRS 253
D + +W+V++
Sbjct: 145 FDETVKIWEVKT 156
Score = 36.6 bits (83), Expect = 0.078
Identities = 48/200 (24%), Positives = 74/200 (37%), Gaps = 27/200 (13%)
Query: 19 CAFSPHSQAYFALASTDGHLRVWETANNRL------HQEYVPSAHL--SGTCT------- 63
C F+P S + S D +++WE + H + V + H SG+
Sbjct: 131 CNFNPPSNLIIS-GSFDETVKIWEVKTGKCLKTLSAHSDPVSAVHFNCSGSLIVSGSYDG 189
Query: 64 -CLAWAPARLQA-KESPQRKKRKSEAVGMSNQTDLLALGTAVGSILLYSTVKGELHSKLI 121
C W A Q K V S + T ++ L+ +G
Sbjct: 190 LCRIWDAASGQCLKTLVDDDNPPVSFVKFSPNGKYILTATLDNTLKLWDYSRGRCLKTYT 249
Query: 122 SGGHDNRVNCI--QWHQDSG-CLYSCSDDKHIVEWNVQTCKVKCKWKGDNSSVSSLCISP 178
GH N CI + G + S S+D + WN+QT ++ K +G V S P
Sbjct: 250 --GHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISAACHP 307
Query: 179 DGKMLLSAG----RTIKLWV 194
++ SA +TIKLW+
Sbjct: 308 TENLIASAALENDKTIKLWM 327
Score = 33.5 bits (75), Expect = 0.66
Identities = 27/96 (28%), Positives = 44/96 (45%), Gaps = 16/96 (16%)
Query: 160 VKCKWKGDNSSVSSLCISPDGKMLL--SAGRTIKLWVLETKEVYRHFTGHATPVSSLMFT 217
+KC G +VSS+ SP+G+ L SA R I +W + + GH +S + ++
Sbjct: 33 LKCTLVGHTEAVSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWS 92
Query: 218 TIRPPNESQPFDGITGLYFLSGAVHDRLLNVWQVRS 253
+ + S+ L A D+ L +W VRS
Sbjct: 93 S----DSSR----------LVSASDDKTLKLWDVRS 114
>gi|21361639 DIPB protein [Homo sapiens]
Length = 344
Score = 62.0 bits (149), Expect = 2e-09
Identities = 32/78 (41%), Positives = 47/78 (60%), Gaps = 2/78 (2%)
Query: 600 EEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDEDAEGKDEENGEDRDTASE 659
EE SEEES+ E + E++ EDE + ESE+D + E EDE +E+N E+ ++ +E
Sbjct: 97 EESESEEESESEEESETEEES--EDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAE 154
Query: 660 KELNGDSDLDPENESEEE 677
E +S+ DPE E E E
Sbjct: 155 GETEAESEFDPEIEMEAE 172
Score = 52.8 bits (125), Expect = 1e-06
Identities = 28/78 (35%), Positives = 42/78 (53%), Gaps = 2/78 (2%)
Query: 600 EEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDEDAEGKDEENGEDRDTASE 659
EE + E + EI + E++ E EEESESE++ + EEE ED ++ E + + E
Sbjct: 79 EEAEVKVEQEREIESEAGEES--ESEEESESEEESETEEESEDESDEESEEDSEEEMEDE 136
Query: 660 KELNGDSDLDPENESEEE 677
+E + D E ESE E
Sbjct: 137 QESEAEEDNQEEGESEAE 154
Score = 46.2 bits (108), Expect = 1e-04
Identities = 26/83 (31%), Positives = 44/83 (53%)
Query: 595 AKLVYEEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDEDAEGKDEENGEDR 654
A+ V+ ++ +D E A K+ + E E E ESE E+ E E+E ++ E E+
Sbjct: 58 AEYVHGSQAWTPPADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEES 117
Query: 655 DTASEKELNGDSDLDPENESEEE 677
+ S++E DS+ + E+E E E
Sbjct: 118 EDESDEESEEDSEEEMEDEQESE 140
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 59.3 bits (142), Expect = 1e-08
Identities = 30/76 (39%), Positives = 48/76 (63%), Gaps = 6/76 (7%)
Query: 600 EEESSEEESDDEIADKDSEDNWDEDEE------ESESEKDEDVEEEDEDAEGKDEENGED 653
EEE EEE ++E +++ E++++E+EE E E E++E+ EEE E+ EG+ EE E+
Sbjct: 889 EEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEE 948
Query: 654 RDTASEKELNGDSDLD 669
D E+EL DL+
Sbjct: 949 EDEEEEEELEEVEDLE 964
Score = 52.4 bits (124), Expect = 1e-06
Identities = 24/64 (37%), Positives = 40/64 (62%)
Query: 614 DKDSEDNWDEDEEESESEKDEDVEEEDEDAEGKDEENGEDRDTASEKELNGDSDLDPENE 673
+++ E+ +E+EEE E E++ED EEE+ED E EE E+ + E+ + +L+ E E
Sbjct: 888 EEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEE 947
Query: 674 SEEE 677
E+E
Sbjct: 948 EEDE 951
Score = 51.2 bits (121), Expect = 3e-06
Identities = 28/78 (35%), Positives = 45/78 (57%), Gaps = 3/78 (3%)
Query: 600 EEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDEDAEGKDEENGEDRDTASE 659
EEE EEE ++E ++ E+ +ED EE E +++E EEE+E+ E +EE E+ E
Sbjct: 888 EEEEEEEEEEEE---EEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEE 944
Query: 660 KELNGDSDLDPENESEEE 677
+E D + + E E E+
Sbjct: 945 EEEEEDEEEEEELEEVED 962
Score = 50.4 bits (119), Expect = 5e-06
Identities = 31/96 (32%), Positives = 53/96 (55%), Gaps = 4/96 (4%)
Query: 583 EKTKGATSPG--QKAKLVYEEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEED 640
E T G P ++ V SS+EE ++E +++ E+ +E+EEE + E++E+ EEE
Sbjct: 863 EGTPGGGGPPALEEDLTVININSSDEEEEEE--EEEEEEEEEEEEEEEDFEEEEEDEEEY 920
Query: 641 EDAEGKDEENGEDRDTASEKELNGDSDLDPENESEE 676
+ E ++EE E+ E EL + + + E E EE
Sbjct: 921 FEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEE 956
Score = 49.7 bits (117), Expect = 9e-06
Identities = 24/70 (34%), Positives = 44/70 (62%)
Query: 608 SDDEIADKDSEDNWDEDEEESESEKDEDVEEEDEDAEGKDEENGEDRDTASEKELNGDSD 667
SD+E +++ E+ +E+EEE E + +E+ E+E+E E ++EE E + E+E + +
Sbjct: 886 SDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEE 945
Query: 668 LDPENESEEE 677
+ E+E EEE
Sbjct: 946 EEEEDEEEEE 955
Score = 42.0 bits (97), Expect = 0.002
Identities = 25/74 (33%), Positives = 40/74 (54%), Gaps = 12/74 (16%)
Query: 600 EEESSEEESDDEIADKDSEDNWDEDEEESE------------SEKDEDVEEEDEDAEGKD 647
EEE EEE D E ++D E+ ++E+EEE E E++E+ E+E+E+ E ++
Sbjct: 900 EEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEE 959
Query: 648 EENGEDRDTASEKE 661
E+ E E E
Sbjct: 960 VEDLEFGTAGGEVE 973
Score = 38.5 bits (88), Expect = 0.021
Identities = 19/53 (35%), Positives = 33/53 (62%), Gaps = 1/53 (1%)
Query: 600 EEESSEEESDDEIADKDSE-DNWDEDEEESESEKDEDVEEEDEDAEGKDEENG 651
EEE EEE ++E +++ E + +E+E+E E E+ E+VE+ + G + E G
Sbjct: 923 EEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEG 975
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 58.2 bits (139), Expect = 3e-08
Identities = 33/99 (33%), Positives = 50/99 (50%), Gaps = 8/99 (8%)
Query: 583 EKTKGATSPGQKAKLVYEEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDED 642
E S QK L +EEE EEE ++E ++D E+ +E+EEE E E++E+ EEE+E+
Sbjct: 241 EDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEE 300
Query: 643 AEGKDE--------ENGEDRDTASEKELNGDSDLDPENE 673
E ++E E+ EL G P+ E
Sbjct: 301 EEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPE 339
Score = 48.9 bits (115), Expect = 2e-05
Identities = 32/108 (29%), Positives = 55/108 (50%), Gaps = 1/108 (0%)
Query: 570 GKLILLITQVTASEKTKGATSPGQKAKLVYEEESSEEESDDEIADKDSEDNWDEDEEESE 629
G+ L I A E + T Q E+++ EES + E+ +E+EEE E
Sbjct: 210 GEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEE-E 268
Query: 630 SEKDEDVEEEDEDAEGKDEENGEDRDTASEKELNGDSDLDPENESEEE 677
E++ED EEE+E+ E ++EE E+ + E+E + + P+ +E+
Sbjct: 269 EEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQED 316
Score = 47.4 bits (111), Expect = 4e-05
Identities = 29/104 (27%), Positives = 52/104 (50%), Gaps = 9/104 (8%)
Query: 583 EKTKGATSPGQKAKLVYEEESSEE------ESDDEIADKDSEDNWDEDEEESE---SEKD 633
E +GA S + L + E +EE E ++ + ED E+ + + S ++
Sbjct: 200 EAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEE 259
Query: 634 EDVEEEDEDAEGKDEENGEDRDTASEKELNGDSDLDPENESEEE 677
ED EEE+E+ E +++E E+ + E+E + + + E E EEE
Sbjct: 260 EDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 303
Score = 29.6 bits (65), Expect = 9.5
Identities = 32/138 (23%), Positives = 47/138 (34%), Gaps = 16/138 (11%)
Query: 538 LSTLPDLVPQLGTLYQLMESRVKTFQKLSHLHGKLILLITQVTASEKTKGATSPGQKAKL 597
LST P +P ++ E+ T H H K ++ + G SP +
Sbjct: 647 LSTKPQDLPSKSVDIEVDENG--TLDLSMHKHRKRENAFPSSSSCSSSPGVKSPDASQRH 704
Query: 598 VYEEESSEEESDDEIADKDSEDNWD-------------EDEEESESEKDEDVEEEDEDAE 644
S + + + +D WD E+ EESE E +D E
Sbjct: 705 SSTSAPSSSMTSPQSSQASRQDEWDRPLDYTKPSRLREEEPEESEPAAHSFASSEADDQE 764
Query: 645 GKDEENGEDRDTASEKEL 662
EEN E+R E L
Sbjct: 765 -VSEENFEERKYPGEVTL 781
>gi|109948304 smu-1 suppressor of mec-8 and unc-52 homolog [Homo
sapiens]
Length = 513
Score = 58.2 bits (139), Expect = 3e-08
Identities = 46/191 (24%), Positives = 82/191 (42%), Gaps = 23/191 (12%)
Query: 17 VPCA-FSPHSQAYFALASTDGHLRVWETANNRLHQEYVPSAHLSGTCTCLAWAPARLQAK 75
V CA FSP Q Y S DG + VW ++ ++ + QA+
Sbjct: 217 VECARFSPDGQ-YLVTGSVDGFIEVWNFTTGKIRKDL------------------KYQAQ 257
Query: 76 ESPQRKKRKSEAVGMSNQTDLLALGTAVGSILLYSTVKGELHSKLISGGHDNRVNCIQWH 135
++ + S T++LA G G I ++ G+ + H V C+ +
Sbjct: 258 DNFMMMDDAVLCMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRF-ERAHSKGVTCLSFS 316
Query: 136 QDSGCLYSCSDDKHIVEWNVQTCKVKCKWKGDNSSVSSLCISPDGKMLLSAGR--TIKLW 193
+DS + S S D+ I +++ K +++G +S V+ + DG ++SA T+K+W
Sbjct: 317 KDSSQILSASFDQTIRIHGLKSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIW 376
Query: 194 VLETKEVYRHF 204
++T E F
Sbjct: 377 NMKTTECSNTF 387
Score = 45.1 bits (105), Expect = 2e-04
Identities = 48/213 (22%), Positives = 93/213 (43%), Gaps = 25/213 (11%)
Query: 81 KKRKSEAVGMSNQTDLLALGTAVGSILLYSTVKGELHSKLISGGHDN------RVNCIQW 134
+K E S L G+ G I +++ G++ L DN V C+ +
Sbjct: 213 QKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCF 272
Query: 135 HQDSGCLYSCSDDKHIVEWNVQTCKVKCKWKGDNSS-VSSLCISPDGKMLLSAG--RTIK 191
+D+ L + + D I W +Q+ + +++ +S V+ L S D +LSA +TI+
Sbjct: 273 SRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIR 332
Query: 192 LWVLETKEVYRHFTGHATPVSSLMFTTIRPPNESQPFDGITGLYFLSGAVHDRLLNVWQV 251
+ L++ + + F GH++ V+ FT DG +++ A D + +W +
Sbjct: 333 IHGLKSGKTLKEFRGHSSFVNEATFTQ----------DG----HYIISASSDGTVKIWNM 378
Query: 252 RSENKEKS--AVMSFTVTDEPVYIDLTLSENKE 282
++ + ++ S TD V + L +N E
Sbjct: 379 KTTECSNTFKSLGSTAGTDITVNSVILLPKNPE 411
Score = 40.0 bits (92), Expect = 0.007
Identities = 35/123 (28%), Positives = 55/123 (44%), Gaps = 11/123 (8%)
Query: 118 SKLISGGHDNRVNCIQWHQDSGCLYSCSDDKHIVEWNVQTCKVKCKWK---GDN-----S 169
S+ I G + V C ++ D L + S D I WN T K++ K DN
Sbjct: 206 SRHIKFGQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDD 265
Query: 170 SVSSLCISPDGKMLLSAGR--TIKLWVLETKEVYRHF-TGHATPVSSLMFTTIRPPNESQ 226
+V +C S D +ML + + IK+W +++ + R F H+ V+ L F+ S
Sbjct: 266 AVLCMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSA 325
Query: 227 PFD 229
FD
Sbjct: 326 SFD 328
>gi|239756368 PREDICTED: similar to acidic (leucine-rich) nuclear
phosphoprotein 32 family, member B [Homo sapiens]
Length = 272
Score = 57.8 bits (138), Expect = 3e-08
Identities = 29/82 (35%), Positives = 51/82 (62%), Gaps = 4/82 (4%)
Query: 600 EEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDEDAEGKDEENGEDRDTASE 659
++E+ + ++ + DK+ ED EDE++ E+E E+ E ++E+ E +D E +D+D SE
Sbjct: 172 DQEAPDSDAQVDGVDKEEEDEEGEDEKDXENEDGEEEELDEEEDEDEDVEGDDDKDEVSE 231
Query: 660 KE----LNGDSDLDPENESEEE 677
+E L+ D D + E+E EEE
Sbjct: 232 EEEEFGLDKDEDDEDEDEDEEE 253
Score = 55.8 bits (133), Expect = 1e-07
Identities = 26/65 (40%), Positives = 40/65 (61%)
Query: 600 EEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDEDAEGKDEENGEDRDTASE 659
EE EE+ D+++ D +D E+EEE +KDED E+EDED E ++ GE+R ++
Sbjct: 208 EELDEEEDEDEDVEGDDDKDEVSEEEEEFGLDKDEDDEDEDEDEEEEESGKGENRKRETD 267
Query: 660 KELNG 664
E +G
Sbjct: 268 DEEDG 272
Score = 48.9 bits (115), Expect = 2e-05
Identities = 31/82 (37%), Positives = 45/82 (54%), Gaps = 5/82 (6%)
Query: 600 EEESSEEESDDEIADKDSED---NWDEDEE-ESESEKDEDVEEEDEDAEGKDEENGEDRD 655
E+E E+E D E D + E+ DEDE+ E + +KDE EEE+E KDE++ ED D
Sbjct: 190 EDEEGEDEKDXENEDGEEEELDEEEDEDEDVEGDDDKDEVSEEEEEFGLDKDEDD-EDED 248
Query: 656 TASEKELNGDSDLDPENESEEE 677
E+E +G + +EE
Sbjct: 249 EDEEEEESGKGENRKRETDDEE 270
Score = 39.3 bits (90), Expect = 0.012
Identities = 25/70 (35%), Positives = 39/70 (55%), Gaps = 8/70 (11%)
Query: 616 DSEDNWDEDEEESESEKD------EDVEEEDE-DAEGKDEENGE-DRDTASEKELNGDSD 667
D+ D D++ +S+++ D ED E EDE D E +D E E D + ++++ GD D
Sbjct: 166 DTYDPEDQEAPDSDAQVDGVDKEEEDEEGEDEKDXENEDGEEEELDEEEDEDEDVEGDDD 225
Query: 668 LDPENESEEE 677
D +E EEE
Sbjct: 226 KDEVSEEEEE 235
>gi|239750893 PREDICTED: similar to acidic (leucine-rich) nuclear
phosphoprotein 32 family, member B [Homo sapiens]
Length = 272
Score = 57.8 bits (138), Expect = 3e-08
Identities = 29/82 (35%), Positives = 51/82 (62%), Gaps = 4/82 (4%)
Query: 600 EEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDEDAEGKDEENGEDRDTASE 659
++E+ + ++ + DK+ ED EDE++ E+E E+ E ++E+ E +D E +D+D SE
Sbjct: 172 DQEAPDSDAQVDGVDKEEEDEEGEDEKDXENEDGEEEELDEEEDEDEDVEGDDDKDEVSE 231
Query: 660 KE----LNGDSDLDPENESEEE 677
+E L+ D D + E+E EEE
Sbjct: 232 EEEEFGLDKDEDDEDEDEDEEE 253
Score = 55.8 bits (133), Expect = 1e-07
Identities = 26/65 (40%), Positives = 40/65 (61%)
Query: 600 EEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDEDAEGKDEENGEDRDTASE 659
EE EE+ D+++ D +D E+EEE +KDED E+EDED E ++ GE+R ++
Sbjct: 208 EELDEEEDEDEDVEGDDDKDEVSEEEEEFGLDKDEDDEDEDEDEEEEESGKGENRKRETD 267
Query: 660 KELNG 664
E +G
Sbjct: 268 DEEDG 272
Score = 48.9 bits (115), Expect = 2e-05
Identities = 31/82 (37%), Positives = 45/82 (54%), Gaps = 5/82 (6%)
Query: 600 EEESSEEESDDEIADKDSED---NWDEDEE-ESESEKDEDVEEEDEDAEGKDEENGEDRD 655
E+E E+E D E D + E+ DEDE+ E + +KDE EEE+E KDE++ ED D
Sbjct: 190 EDEEGEDEKDXENEDGEEEELDEEEDEDEDVEGDDDKDEVSEEEEEFGLDKDEDD-EDED 248
Query: 656 TASEKELNGDSDLDPENESEEE 677
E+E +G + +EE
Sbjct: 249 EDEEEEESGKGENRKRETDDEE 270
Score = 39.3 bits (90), Expect = 0.012
Identities = 25/70 (35%), Positives = 39/70 (55%), Gaps = 8/70 (11%)
Query: 616 DSEDNWDEDEEESESEKD------EDVEEEDE-DAEGKDEENGE-DRDTASEKELNGDSD 667
D+ D D++ +S+++ D ED E EDE D E +D E E D + ++++ GD D
Sbjct: 166 DTYDPEDQEAPDSDAQVDGVDKEEEDEEGEDEKDXENEDGEEEELDEEEDEDEDVEGDDD 225
Query: 668 LDPENESEEE 677
D +E EEE
Sbjct: 226 KDEVSEEEEE 235
>gi|4557741 platelet-activating factor acetylhydrolase, isoform Ib,
alpha subunit [Homo sapiens]
Length = 410
Score = 57.4 bits (137), Expect = 4e-08
Identities = 63/233 (27%), Positives = 98/233 (42%), Gaps = 31/233 (13%)
Query: 119 KLISGGHDNRVNCIQWHQDSGCLYSCSDDKHIVEWNVQTCKVKCKWKGDNSSVSSLCISP 178
K GH + V + +H + S S+D I W+ +T + KG SV +
Sbjct: 101 KYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDH 160
Query: 179 DGKML--LSAGRTIKLWVLETKEVYRHFTGHATPVSSLMFTTIRPPNESQPFDGITGLYF 236
GK+L SA TIKLW + E R GH VSS+ I P +
Sbjct: 161 SGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSV---AIMPNGD-----------H 206
Query: 237 LSGAVHDRLLNVWQVRSENKEKSAVMSFTVTDEPVYI-------DLTLSENKEEPVKLAV 289
+ A D+ + +W+V++ V +FT E V + L S + ++ V++ V
Sbjct: 207 IVSASRDKTIKMWEVQT----GYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWV 262
Query: 290 VCR---DGQVHLFEHILNGYCKKPLTSNCTIQIATPGKGKKSTPKPIPILAAG 339
V ++ EH++ P +S +I AT + KKS KP P L +G
Sbjct: 263 VATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKS-GKPGPFLLSG 314
Score = 47.8 bits (112), Expect = 3e-05
Identities = 40/166 (24%), Positives = 66/166 (39%), Gaps = 10/166 (6%)
Query: 30 ALASTDGHLRVWETANNRLHQEYVPSAHLSGTCTCLAWAPARLQAKESPQRKKRKSEAVG 89
A S D +RVW A E H+ C++WAP ++ S + SE
Sbjct: 250 ASCSNDQTVRVWVVATKECKAELREHEHV---VECISWAP---ESSYSSISEATGSETKK 303
Query: 90 MSNQTDLLALGTAVGSILLYSTVKGELHSKLISGGHDNRVNCIQWHQDSGCLYSCSDDKH 149
L G+ +I ++ G L+ GHDN V + +H + SC+DDK
Sbjct: 304 SGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLV--GHDNWVRGVLFHSGGKFILSCADDKT 361
Query: 150 IVEWNVQTCKVKCKWKGDNSSVSSLCISPDGKMLL--SAGRTIKLW 193
+ W+ + + V+SL ++ S +T+K+W
Sbjct: 362 LRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW 407
Score = 40.8 bits (94), Expect = 0.004
Identities = 37/150 (24%), Positives = 58/150 (38%), Gaps = 36/150 (24%)
Query: 125 HDNRVNCIQWHQDSGC--------------------LYSCSDDKHIVEWNVQTCKVKCKW 164
H++ V CI W +S L S S DK I W+V T
Sbjct: 275 HEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTL 334
Query: 165 KGDNSSVSSLCISPDGKMLLSAG--RTIKLWVLETKEVYRHFTGHATPVSSLMFTTIRPP 222
G ++ V + GK +LS +T+++W + K + H V+SL F P
Sbjct: 335 VGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAP- 393
Query: 223 NESQPFDGITGLYFLSGAVHDRLLNVWQVR 252
Y ++G+V D+ + VW+ R
Sbjct: 394 ------------YVVTGSV-DQTVKVWECR 410
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 57.0 bits (136), Expect = 6e-08
Identities = 33/92 (35%), Positives = 50/92 (54%), Gaps = 6/92 (6%)
Query: 592 GQKAKLVYEEESSEEESDD-EIADKDSEDNWDEDEEESESEKDEDVEEEDEDAEGKDEE- 649
G++ + EEE E E +D E ++ E W+ +EEE E E +E+ E E E+ EG+ EE
Sbjct: 925 GEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEE 984
Query: 650 ----NGEDRDTASEKELNGDSDLDPENESEEE 677
GE+ + E E G+ + + E E EEE
Sbjct: 985 EGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEE 1016
Score = 56.6 bits (135), Expect = 7e-08
Identities = 32/92 (34%), Positives = 49/92 (53%), Gaps = 1/92 (1%)
Query: 586 KGATSPGQKAKLVYEEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDEDAEG 645
+G G++ E E EEE + E +++ E +E+E E E E++ + E E+E+ EG
Sbjct: 861 EGEEGEGEEEGEEGEGEGEEEEGEGE-GEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEG 919
Query: 646 KDEENGEDRDTASEKELNGDSDLDPENESEEE 677
K EE GE+ + E+E D E E EEE
Sbjct: 920 KGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEE 951
Score = 53.1 bits (126), Expect = 8e-07
Identities = 31/78 (39%), Positives = 44/78 (56%), Gaps = 3/78 (3%)
Query: 600 EEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDEDAEGKDEENGEDRDTASE 659
EEE EEE ++E + E+ E EEE E E + +VE E+ + EG++EE GE+ E
Sbjct: 991 EEEEGEEEGEEE--GEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEE-GEEEGEERE 1047
Query: 660 KELNGDSDLDPENESEEE 677
KE G+ + E EEE
Sbjct: 1048 KEGEGEENRRNREEEEEE 1065
Score = 51.2 bits (121), Expect = 3e-06
Identities = 29/89 (32%), Positives = 44/89 (49%), Gaps = 11/89 (12%)
Query: 600 EEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVE-----------EEDEDAEGKDE 648
EEE E D E ++ E W+ +EEE E E +E+ E EE+ + EG++E
Sbjct: 934 EEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEE 993
Query: 649 ENGEDRDTASEKELNGDSDLDPENESEEE 677
E E+ + E E G+ + + E E E E
Sbjct: 994 EGEEEGEEEGEGEEEGEGEGEEEEEGEVE 1022
Score = 50.4 bits (119), Expect = 5e-06
Identities = 29/79 (36%), Positives = 44/79 (55%), Gaps = 3/79 (3%)
Query: 600 EEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDEDAEGKDEENGEDRDTASE 659
EEE E E ++E ++ E +E+E E E E++ + E E+E+ EG+ EE GE E
Sbjct: 859 EEEGEEGEGEEE--GEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEE 916
Query: 660 KELNGDSD-LDPENESEEE 677
E G+ + + E E EEE
Sbjct: 917 GEGKGEEEGEEGEGEGEEE 935
Score = 50.1 bits (118), Expect = 7e-06
Identities = 34/102 (33%), Positives = 51/102 (50%), Gaps = 5/102 (4%)
Query: 577 TQVTASEKTKGATSPGQKAKLVYEEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDV 636
T+ EK +G G + V E + EE ++E ++ E +E+E E E E+ E
Sbjct: 801 TEGRGEEKEEGGEVEGGE---VEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGK 857
Query: 637 -EEEDEDAEGKDEENGEDRDTASEKELNGDSDLDPENESEEE 677
EEE E+ EG +EE E E+E G+ + + E E EEE
Sbjct: 858 GEEEGEEGEG-EEEGEEGEGEGEEEEGEGEGEEEGEGEGEEE 898
Score = 49.3 bits (116), Expect = 1e-05
Identities = 30/93 (32%), Positives = 45/93 (48%), Gaps = 8/93 (8%)
Query: 592 GQKAKLVYEEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEE--------EDEDA 643
G++ + E E EEE + E + + E+ E + E E E+ E EE E+E+
Sbjct: 824 GEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEG 883
Query: 644 EGKDEENGEDRDTASEKELNGDSDLDPENESEE 676
EG+ EE GE E E G+ + + E E EE
Sbjct: 884 EGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEE 916
Score = 46.6 bits (109), Expect = 8e-05
Identities = 28/78 (35%), Positives = 42/78 (53%), Gaps = 4/78 (5%)
Query: 600 EEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDEDAEGKDEENGEDRDTASE 659
E E EE + E +++ E +E+E E E E++ + EEE E EG++EE GE
Sbjct: 969 EGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGE-GEGEEEEEGEVEGEVEG 1027
Query: 660 KELNGDSDLDPENESEEE 677
+E G+ + E E EEE
Sbjct: 1028 EEGEGEGE---EEEGEEE 1042
Score = 45.1 bits (105), Expect = 2e-04
Identities = 30/108 (27%), Positives = 48/108 (44%), Gaps = 13/108 (12%)
Query: 583 EKTKGATS---PGQKAKLVYEEESSEEESDDEIADKDSEDNWDED----------EEESE 629
EK KG PG+ K + E+E ++ +E K+ E ++ EE E
Sbjct: 678 EKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGE 737
Query: 630 SEKDEDVEEEDEDAEGKDEENGEDRDTASEKELNGDSDLDPENESEEE 677
E++E EE+E+ EG+ +E GE + E+E E +EE
Sbjct: 738 GEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEE 785
Score = 44.7 bits (104), Expect = 3e-04
Identities = 28/98 (28%), Positives = 47/98 (47%), Gaps = 3/98 (3%)
Query: 583 EKTKGATSPGQKAKLVYEEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDED 642
E +G G + + +E +EE + E + + E E ++E + K+E EEE +
Sbjct: 734 EHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQ 793
Query: 643 AEGKDEE---NGEDRDTASEKELNGDSDLDPENESEEE 677
EG++EE GE+++ E E + E E EEE
Sbjct: 794 GEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEE 831
Score = 44.7 bits (104), Expect = 3e-04
Identities = 25/77 (32%), Positives = 41/77 (53%), Gaps = 1/77 (1%)
Query: 600 EEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDEDAEGKDEENGEDRDTASE 659
EEE E ++E + + E +E E E E E+ E+ E E+ + EG+ EEN +R+ E
Sbjct: 1006 EEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEE-EGEEREKEGEGEENRRNREEEEE 1064
Query: 660 KELNGDSDLDPENESEE 676
+E + ENE ++
Sbjct: 1065 EEGKYQETGEEENERQD 1081
Score = 44.3 bits (103), Expect = 4e-04
Identities = 21/62 (33%), Positives = 36/62 (58%)
Query: 600 EEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDEDAEGKDEENGEDRDTASE 659
E E EE + E +++ E+ +E E+E E E++ EE+E+ EGK +E GE+ + +
Sbjct: 1022 EGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQD 1081
Query: 660 KE 661
E
Sbjct: 1082 GE 1083
Score = 43.9 bits (102), Expect = 5e-04
Identities = 31/101 (30%), Positives = 50/101 (49%), Gaps = 10/101 (9%)
Query: 583 EKTKGATSPGQKAKLVYEEESSEEESDD-EIADKDSEDNWDEDEEESESEKDE------D 635
EK +G ++A +EE EEE D E ++++E +E EE E E E +
Sbjct: 769 EKEEGERKKEERAG---KEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGE 825
Query: 636 VEEEDEDAEGKDEENGEDRDTASEKELNGDSDLDPENESEE 676
EEE+E+ EG++EE + + +E G+ + E E E
Sbjct: 826 REEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGE 866
Score = 43.9 bits (102), Expect = 5e-04
Identities = 28/78 (35%), Positives = 42/78 (53%), Gaps = 2/78 (2%)
Query: 600 EEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDEDAEGKDEENGEDRDTASE 659
E E EEE + + ++ E + +EEE E E ED E E E+ EG+ E E+ + E
Sbjct: 909 EGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGE-GEDGEGEGEEEEGEWEGEEEEGEGEGE 967
Query: 660 KELNGDSDLDPENESEEE 677
+E G+ + + E E EEE
Sbjct: 968 EEGEGEGE-EGEGEGEEE 984
Score = 43.9 bits (102), Expect = 5e-04
Identities = 27/81 (33%), Positives = 43/81 (53%), Gaps = 8/81 (9%)
Query: 600 EEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEE---EDEDAEGKDEENGEDRDT 656
EEE E E ++E + + E+ + + EE E E +E+ E E+E+ E + EE GE
Sbjct: 949 EEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGE---- 1004
Query: 657 ASEKELNGDSDLDPENESEEE 677
E+E G+ + + E E E E
Sbjct: 1005 -GEEEGEGEGEEEEEGEVEGE 1024
Score = 43.5 bits (101), Expect = 6e-04
Identities = 33/100 (33%), Positives = 49/100 (49%), Gaps = 15/100 (15%)
Query: 592 GQKAKLVYEEESSEEESDDE-IADKDSEDNWDEDEEESESEKDEDV-----EEEDEDAEG 645
G++ + EEE E E ++E + + E+ E EEE E E +E+ EEE E+ EG
Sbjct: 871 GEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEG 930
Query: 646 KDE--------ENGEDRDTASEKELNGDSDLDPENESEEE 677
+ E E+GE E E G+ + + E E EEE
Sbjct: 931 EGEEEEGEGEGEDGEGEGEEEEGEWEGEEE-EGEGEGEEE 969
Score = 42.7 bits (99), Expect = 0.001
Identities = 27/91 (29%), Positives = 44/91 (48%), Gaps = 1/91 (1%)
Query: 586 KGATSPGQKAKLVYEEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDEDAEG 645
+G G+ + E E EEE + E +++ E +E E E E E+ E EE+E E
Sbjct: 940 EGEDGEGEGEEEEGEWEGEEEEGEGE-GEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEE 998
Query: 646 KDEENGEDRDTASEKELNGDSDLDPENESEE 676
+EE + + E E + +++ E E EE
Sbjct: 999 GEEEGEGEEEGEGEGEEEEEGEVEGEVEGEE 1029
Score = 42.4 bits (98), Expect = 0.001
Identities = 32/101 (31%), Positives = 50/101 (49%), Gaps = 10/101 (9%)
Query: 583 EKTKGATSPGQKAKLVYEEESSEEESDDEIADKDSEDNW---DEDEEESESEKDEDVEEE 639
EK + G+ + E E+E E+ + E+ +E+EEE E E++E E E
Sbjct: 785 EKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEG-EGE 843
Query: 640 DEDAEGKDEE---NGEDRDTASEKELNGDSDLDPENESEEE 677
+E+ EG++EE GE+ E E G+ + E E EEE
Sbjct: 844 EEEGEGEEEEGEGKGEEEGEEGEGEEEGE---EGEGEGEEE 881
Score = 42.4 bits (98), Expect = 0.001
Identities = 26/81 (32%), Positives = 42/81 (51%), Gaps = 4/81 (4%)
Query: 600 EEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDEDAEGKD-EENGEDRD--- 655
EEE E E ++E + E+ + EE E + + EEE+ + EG+D E GE+ +
Sbjct: 896 EEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEW 955
Query: 656 TASEKELNGDSDLDPENESEE 676
E+E G+ + + E E EE
Sbjct: 956 EGEEEEGEGEGEEEGEGEGEE 976
Score = 42.4 bits (98), Expect = 0.001
Identities = 28/78 (35%), Positives = 42/78 (53%), Gaps = 4/78 (5%)
Query: 601 EESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDEDAEGKDEENGEDRDTASEK 660
E EEE + E + + E +E E E E E+ E EE +E+ EG++E GE + E
Sbjct: 963 EGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGE--EEGEEEGEGEEEGEGEGEE-EEEG 1019
Query: 661 ELNGDSD-LDPENESEEE 677
E+ G+ + + E E EEE
Sbjct: 1020 EVEGEVEGEEGEGEGEEE 1037
Score = 40.4 bits (93), Expect = 0.005
Identities = 32/106 (30%), Positives = 48/106 (45%), Gaps = 18/106 (16%)
Query: 583 EKTKGATSPGQKAKLVYEEESSEEESDDEIADKDSEDNWD-EDEEESESEKDEDVEEEDE 641
E+ KG G+ E E + E+A+K+ D E++E+ E E+ E E
Sbjct: 673 EREKGEKDKGRG------EMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQE 726
Query: 642 DAEGKDEENGE------DRDTASEKELNG-----DSDLDPENESEE 676
EG +EE+GE DR+ EKE G +++ E E EE
Sbjct: 727 MEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEE 772
Score = 40.4 bits (93), Expect = 0.005
Identities = 23/69 (33%), Positives = 37/69 (53%), Gaps = 1/69 (1%)
Query: 600 EEESSEEESDDEIADKDSEDNWDEDEEESES-EKDEDVEEEDEDAEGKDEENGEDRDTAS 658
EEE E E + E + + E +E EEE E EK+ + EE + E ++EE G+ ++T
Sbjct: 1015 EEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGE 1074
Query: 659 EKELNGDSD 667
E+ D +
Sbjct: 1075 EENERQDGE 1083
Score = 38.5 bits (88), Expect = 0.021
Identities = 25/89 (28%), Positives = 43/89 (48%), Gaps = 4/89 (4%)
Query: 593 QKAKLVYEEESSEEE---SDDEIADKDSEDNWD-EDEEESESEKDEDVEEEDEDAEGKDE 648
QK + EE EEE ++E D++ E+ + E +EE E E+ E E++E K+E
Sbjct: 720 QKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEE 779
Query: 649 ENGEDRDTASEKELNGDSDLDPENESEEE 677
G++ E + + + E EE+
Sbjct: 780 RAGKEEKGEEEGDQGEGEEEETEGRGEEK 808
Score = 37.7 bits (86), Expect = 0.035
Identities = 30/96 (31%), Positives = 44/96 (45%), Gaps = 8/96 (8%)
Query: 583 EKTKGATSPGQKAKLVYEEESSE-EESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDE 641
EK G+ ++ E E E E +E A K+ + + D+ E E E+ E EE E
Sbjct: 750 EKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKE 809
Query: 642 DAEGKDEENGEDRDTASEKELNGDSDLDPENESEEE 677
EG + E GE + E+E + + E E EEE
Sbjct: 810 --EGGEVEGGEVEEGKGERE-----EEEEEGEGEEE 838
Score = 37.7 bits (86), Expect = 0.035
Identities = 25/88 (28%), Positives = 45/88 (51%), Gaps = 5/88 (5%)
Query: 592 GQKAKLVYEEESSEEESDDEIA-DKDSEDNWDEDE-EESESEKDEDVEEEDEDAEGKDEE 649
G++ + E+E E + ++ ++ E+ D+ E EE E+E + +EE + EG + E
Sbjct: 761 GEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVE 820
Query: 650 NGEDRDTASEKELNGDSDLDPENESEEE 677
G+ E+E G+ + E E EEE
Sbjct: 821 EGKGEREEEEEEGEGEEE---EGEGEEE 845
Score = 36.6 bits (83), Expect = 0.078
Identities = 32/128 (25%), Positives = 54/128 (42%), Gaps = 27/128 (21%)
Query: 577 TQVTASEKTKGATSPGQKAKLVYEEESSEEESDDEIADKDSE--DNW-DEDEEESE---- 629
T++ + + T A KAK V E E E D ++ S ++W DE+ E+ E
Sbjct: 623 TEILSDDLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKG 682
Query: 630 --------------SEKDEDVEEEDEDAEGKDEENGEDRDTASEKELNGDSDL------D 669
+EK+E + + E+ E K+ E G ++ E E G+ + +
Sbjct: 683 RGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEE 742
Query: 670 PENESEEE 677
+ E EEE
Sbjct: 743 GDREEEEE 750
Score = 32.0 bits (71), Expect = 1.9
Identities = 20/64 (31%), Positives = 35/64 (54%), Gaps = 3/64 (4%)
Query: 584 KTKGATSPGQKAKLVYEEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDEDA 643
+ +G G+ + EEE E E + E +++ N +E+EEE E + E EEE+E
Sbjct: 1024 EVEGEEGEGEGEEEEGEEEGEEREKEGE--GEENRRNREEEEEE-EGKYQETGEEENERQ 1080
Query: 644 EGKD 647
+G++
Sbjct: 1081 DGEE 1084
>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
Length = 1184
Score = 57.0 bits (136), Expect = 6e-08
Identities = 28/77 (36%), Positives = 47/77 (61%), Gaps = 5/77 (6%)
Query: 601 EESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDEDAEGKDEENGED-RDTASE 659
+E E+E ++ D D + DE++EE + E++E++EEEDED D+E+GED D E
Sbjct: 100 DEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDED----DDEDGEDVEDEEEE 155
Query: 660 KELNGDSDLDPENESEE 676
+E + + + ENE +
Sbjct: 156 EEEEEEEEEEEENEDHQ 172
Score = 54.7 bits (130), Expect = 3e-07
Identities = 29/95 (30%), Positives = 49/95 (51%)
Query: 583 EKTKGATSPGQKAKLVYEEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDED 642
+K +P +K V + SS +E DD +D ++ +++ EE + DE +E++ED
Sbjct: 65 DKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEED 124
Query: 643 AEGKDEENGEDRDTASEKELNGDSDLDPENESEEE 677
EG EE E + + + +G+ D E E EEE
Sbjct: 125 EEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEE 159
Score = 53.9 bits (128), Expect = 5e-07
Identities = 31/76 (40%), Positives = 45/76 (59%), Gaps = 4/76 (5%)
Query: 600 EEESSEE--ESDDEIADKDSED-NWDEDEEESESEKDEDVEEEDEDAEGKDEENGEDRDT 656
EE+ EE E +DE D+D ED D +EEE E+DED +E+ ED E ++EE E+ +
Sbjct: 103 EEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEE 162
Query: 657 ASEKELNGDSDLDPEN 672
E+E N D ++ N
Sbjct: 163 EEEEE-NEDHQMNCHN 177
Score = 51.6 bits (122), Expect = 2e-06
Identities = 24/79 (30%), Positives = 45/79 (56%), Gaps = 4/79 (5%)
Query: 601 EESSEEESDDEIADKDSEDNWDE----DEEESESEKDEDVEEEDEDAEGKDEENGEDRDT 656
+E +E+ +DE D++ E+ +E D+E+ E +DE+ EEE+E+ E ++EEN + +
Sbjct: 115 DEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMN 174
Query: 657 ASEKELNGDSDLDPENESE 675
+ D++ D N E
Sbjct: 175 CHNTRIMQDTEKDDNNNDE 193
Score = 48.1 bits (113), Expect = 3e-05
Identities = 30/73 (41%), Positives = 43/73 (58%), Gaps = 3/73 (4%)
Query: 601 EESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDEDAEGKDEENGEDRDTASEK 660
EE E E +DE D+D ED DE+EEE E E++E+ EEE+ED + +DT EK
Sbjct: 130 EEEEEIEEEDEDDDEDGEDVEDEEEEE-EEEEEEEEEEENEDHQMNCHNTRIMQDT--EK 186
Query: 661 ELNGDSDLDPENE 673
+ N + + D +E
Sbjct: 187 DDNNNDEYDNYDE 199
Score = 39.3 bits (90), Expect = 0.012
Identities = 18/66 (27%), Positives = 37/66 (56%), Gaps = 5/66 (7%)
Query: 598 VYEEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEED----EDAEGKDEENGED 653
+ EE+ ++E +++ D++ E+ +E+EEE E +D + + +D E KD+ N ++
Sbjct: 135 IEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTE-KDDNNNDE 193
Query: 654 RDTASE 659
D E
Sbjct: 194 YDNYDE 199
Score = 33.5 bits (75), Expect = 0.66
Identities = 24/104 (23%), Positives = 50/104 (48%), Gaps = 11/104 (10%)
Query: 583 EKTKGATSPGQKAKLVYEEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDED 642
E+ + G+ + EEE EEE ++E ++D + N ++EKD++ +E ++
Sbjct: 137 EEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDN 196
Query: 643 AE----------GKDEENGEDRDTASEKELNGDSDLDPENESEE 676
+ GK E+ R +E E+N ++ E++S++
Sbjct: 197 YDELVAKSLLNLGKIAEDAAYR-ARTESEMNSNTSNSLEDDSDK 239
>gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 family,
member B [Homo sapiens]
Length = 251
Score = 56.6 bits (135), Expect = 7e-08
Identities = 34/82 (41%), Positives = 44/82 (53%), Gaps = 5/82 (6%)
Query: 599 YEEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEED---EDAEGKDEENGEDRD 655
Y+ E E D D E+ DE+ E+ E E DED EEE+ ED E +D E ED D
Sbjct: 148 YDREDQEAPDSDAEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDDD 207
Query: 656 TASEKELNGDSDLDPENESEEE 677
SE+E + LD E+E E+E
Sbjct: 208 EVSEEE--EEFGLDEEDEDEDE 227
Score = 56.6 bits (135), Expect = 7e-08
Identities = 27/78 (34%), Positives = 47/78 (60%)
Query: 600 EEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDEDAEGKDEENGEDRDTASE 659
++E+ + +++ + D++ ED EDEE+ + E E+ E ++ED E +D E ED D SE
Sbjct: 152 DQEAPDSDAEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDDDEVSE 211
Query: 660 KELNGDSDLDPENESEEE 677
+E D + E+E E+E
Sbjct: 212 EEEEFGLDEEDEDEDEDE 229
Score = 52.4 bits (124), Expect = 1e-06
Identities = 27/81 (33%), Positives = 48/81 (59%), Gaps = 4/81 (4%)
Query: 600 EEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDEDAEGKDEENGEDRDTASE 659
EE EE+ DDE +++ D D+++E+ E ++D+D E+E+ G DEE+ ED D E
Sbjct: 172 EEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDDDEVSEEEEEFGLDEED-EDEDEDEE 230
Query: 660 KELNGDSD---LDPENESEEE 677
+E G + + ++E E++
Sbjct: 231 EEEGGKGEKRKRETDDEGEDD 251
Score = 51.6 bits (122), Expect = 2e-06
Identities = 30/73 (41%), Positives = 45/73 (61%), Gaps = 8/73 (10%)
Query: 605 EEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDEDAEGKDEENGEDRDTASEKELNG 664
EEE D+E D++ ED DED EE E ++++D EDED EG ++ +D + E+E
Sbjct: 167 EEEEDEEGEDEEDED--DEDGEEEEFDEEDD---EDEDVEGDED---DDEVSEEEEEFGL 218
Query: 665 DSDLDPENESEEE 677
D + + E+E EEE
Sbjct: 219 DEEDEDEDEDEEE 231
Score = 49.7 bits (117), Expect = 9e-06
Identities = 30/79 (37%), Positives = 46/79 (58%), Gaps = 13/79 (16%)
Query: 600 EEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVE--EEDEDAEGKDEENGEDRDTA 657
+EE +EE +DE D+D ED +E+E + E ++DEDVE E+D++ ++EE G D +
Sbjct: 166 DEEEEDEEGEDE-EDEDDEDG-EEEEFDEEDDEDEDVEGDEDDDEVSEEEEEFGLDEE-- 221
Query: 658 SEKELNGDSDLDPENESEE 676
D D D + E EE
Sbjct: 222 -------DEDEDEDEEEEE 233
Score = 44.7 bits (104), Expect = 3e-04
Identities = 23/63 (36%), Positives = 39/63 (61%), Gaps = 2/63 (3%)
Query: 616 DSEDNWDEDEEESESEKDEDVEEEDEDAEGKDEENGEDRDTASEK-ELNGDSDLDPENES 674
D D D++ +S++E D V+EE+ED EG+DEE+ +D D E+ + D D D E +
Sbjct: 146 DGYDREDQEAPDSDAEVD-GVDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDE 204
Query: 675 EEE 677
+++
Sbjct: 205 DDD 207
>gi|16554629 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 56.2 bits (134), Expect = 1e-07
Identities = 36/151 (23%), Positives = 70/151 (46%), Gaps = 4/151 (2%)
Query: 87 AVGMSNQTDLLALGTAVGSILLYSTVKGELHSKLISGGHDNRVNCIQWHQDSGCLYSCSD 146
+V S + LA +A I ++ G+ + GH ++ + W DS L S SD
Sbjct: 50 SVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTI--SGHKLGISDVAWSSDSNLLVSASD 107
Query: 147 DKHIVEWNVQTCKVKCKWKGDNSSVSSLCISPDGKMLLSAG--RTIKLWVLETKEVYRHF 204
DK + W+V + K KG ++ V +P +++S ++++W ++T + +
Sbjct: 108 DKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTL 167
Query: 205 TGHATPVSSLMFTTIRPPNESQPFDGITGLY 235
H+ PVS++ F S +DG+ ++
Sbjct: 168 PAHSDPVSAVHFNRDGSLIVSSSYDGLCRIW 198
Score = 41.2 bits (95), Expect = 0.003
Identities = 27/102 (26%), Positives = 45/102 (44%), Gaps = 2/102 (1%)
Query: 112 VKGELHSKLISGGHDNRVNCIQWHQDSGCLYSCSDDKHIVEWNVQTCKVKCKWKGDNSSV 171
VK K GH V+ +++ + L S S DK I W K + G +
Sbjct: 31 VKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGI 90
Query: 172 SSLCISPDGKMLLSAG--RTIKLWVLETKEVYRHFTGHATPV 211
S + S D +L+SA +T+K+W + + + + GH+ V
Sbjct: 91 SDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYV 132
Score = 37.0 bits (84), Expect = 0.060
Identities = 47/199 (23%), Positives = 73/199 (36%), Gaps = 27/199 (13%)
Query: 19 CAFSPHSQAYFALASTDGHLRVWETANNRL------HQEYVPSAHLSGTCT--------- 63
C F+P S + S D +R+W+ + H + V + H + +
Sbjct: 135 CNFNPQSNLIVS-GSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDG 193
Query: 64 -CLAWAPARLQA-KESPQRKKRKSEAVGMSNQTDLLALGTAVGSILLYSTVKGELHSKLI 121
C W A Q K V S + T ++ L+ KG+
Sbjct: 194 LCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYT 253
Query: 122 SGGHDNRVNCI--QWHQDSG-CLYSCSDDKHIVEWNVQTCKVKCKWKGDNSSVSSLCISP 178
GH N CI + G + S S+D + WN+QT ++ K +G V S P
Sbjct: 254 --GHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHP 311
Query: 179 DGKMLLSAG----RTIKLW 193
++ SA +TIKLW
Sbjct: 312 TENIIASAALENDKTIKLW 330
>gi|16554627 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 56.2 bits (134), Expect = 1e-07
Identities = 36/151 (23%), Positives = 70/151 (46%), Gaps = 4/151 (2%)
Query: 87 AVGMSNQTDLLALGTAVGSILLYSTVKGELHSKLISGGHDNRVNCIQWHQDSGCLYSCSD 146
+V S + LA +A I ++ G+ + GH ++ + W DS L S SD
Sbjct: 50 SVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTI--SGHKLGISDVAWSSDSNLLVSASD 107
Query: 147 DKHIVEWNVQTCKVKCKWKGDNSSVSSLCISPDGKMLLSAG--RTIKLWVLETKEVYRHF 204
DK + W+V + K KG ++ V +P +++S ++++W ++T + +
Sbjct: 108 DKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTL 167
Query: 205 TGHATPVSSLMFTTIRPPNESQPFDGITGLY 235
H+ PVS++ F S +DG+ ++
Sbjct: 168 PAHSDPVSAVHFNRDGSLIVSSSYDGLCRIW 198
Score = 41.2 bits (95), Expect = 0.003
Identities = 27/102 (26%), Positives = 45/102 (44%), Gaps = 2/102 (1%)
Query: 112 VKGELHSKLISGGHDNRVNCIQWHQDSGCLYSCSDDKHIVEWNVQTCKVKCKWKGDNSSV 171
VK K GH V+ +++ + L S S DK I W K + G +
Sbjct: 31 VKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGI 90
Query: 172 SSLCISPDGKMLLSAG--RTIKLWVLETKEVYRHFTGHATPV 211
S + S D +L+SA +T+K+W + + + + GH+ V
Sbjct: 91 SDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYV 132
Score = 37.0 bits (84), Expect = 0.060
Identities = 47/199 (23%), Positives = 73/199 (36%), Gaps = 27/199 (13%)
Query: 19 CAFSPHSQAYFALASTDGHLRVWETANNRL------HQEYVPSAHLSGTCT--------- 63
C F+P S + S D +R+W+ + H + V + H + +
Sbjct: 135 CNFNPQSNLIVS-GSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDG 193
Query: 64 -CLAWAPARLQA-KESPQRKKRKSEAVGMSNQTDLLALGTAVGSILLYSTVKGELHSKLI 121
C W A Q K V S + T ++ L+ KG+
Sbjct: 194 LCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYT 253
Query: 122 SGGHDNRVNCI--QWHQDSG-CLYSCSDDKHIVEWNVQTCKVKCKWKGDNSSVSSLCISP 178
GH N CI + G + S S+D + WN+QT ++ K +G V S P
Sbjct: 254 --GHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHP 311
Query: 179 DGKMLLSAG----RTIKLW 193
++ SA +TIKLW
Sbjct: 312 TENIIASAALENDKTIKLW 330
>gi|21735415 centromere protein B [Homo sapiens]
Length = 599
Score = 55.8 bits (133), Expect = 1e-07
Identities = 24/61 (39%), Positives = 40/61 (65%)
Query: 617 SEDNWDEDEEESESEKDEDVEEEDEDAEGKDEENGEDRDTASEKELNGDSDLDPENESEE 676
SE +E+EEE E E++ + EEE+E+ E ++EE GE + E+E+ + D+D + E EE
Sbjct: 403 SEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEE 462
Query: 677 E 677
+
Sbjct: 463 D 463
Score = 52.0 bits (123), Expect = 2e-06
Identities = 29/78 (37%), Positives = 43/78 (55%), Gaps = 14/78 (17%)
Query: 600 EEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDEDAEGKDEENGEDRDTASE 659
+ E EEE ++E +E+EEE E E++E+ EE+E+ G+ EE GE+ + E
Sbjct: 402 KSEGEEEEEEEE----------EEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEE 451
Query: 660 KELNGDSDLDPENESEEE 677
GD D D E E +EE
Sbjct: 452 ----GDVDSDEEEEEDEE 465
Score = 43.9 bits (102), Expect = 5e-04
Identities = 36/139 (25%), Positives = 62/139 (44%), Gaps = 42/139 (30%)
Query: 579 VTASEKTKGATSPGQKAKLVYEEESSEEESDDEIADKDSEDNWDEDE--EESESEKDEDV 636
+T S K++G ++ + EEE E E ++E +++ E+ + +E EE E E++ DV
Sbjct: 397 ITTSLKSEGEEEEEEEEE--EEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDV 454
Query: 637 ---EEEDEDAEGKDE-----------------------------------ENGEDRDTAS 658
EEE+ED E E E GED D+ S
Sbjct: 455 DSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDS 514
Query: 659 EKELNGDSDLDPENESEEE 677
E+E + + D + E++ ++E
Sbjct: 515 EEEDDEEEDDEDEDDDDDE 533
Score = 36.2 bits (82), Expect = 0.10
Identities = 17/48 (35%), Positives = 26/48 (54%)
Query: 587 GATSPGQKAKLVYEEESSEEESDDEIADKDSEDNWDEDEEESESEKDE 634
GA Q L + E + +SD E D + ED+ DED+++ E + DE
Sbjct: 491 GAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDE 538
Score = 34.7 bits (78), Expect = 0.30
Identities = 13/29 (44%), Positives = 21/29 (72%)
Query: 614 DKDSEDNWDEDEEESESEKDEDVEEEDED 642
D DS+ ++DEEE + ++D+D +EED D
Sbjct: 509 DSDSDSEEEDDEEEDDEDEDDDDDEEDGD 537
Score = 33.9 bits (76), Expect = 0.51
Identities = 25/98 (25%), Positives = 37/98 (37%), Gaps = 45/98 (45%)
Query: 601 EESSEEESDDEIADKDSEDNWDEDEE---------------------------------- 626
EE EEE +E D DS++ +EDEE
Sbjct: 440 EELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCP 499
Query: 627 -----------ESESEKDEDVEEEDEDAEGKDEENGED 653
+S+SE+++D EE+DED + D+E D
Sbjct: 500 TLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGD 537
Score = 33.5 bits (75), Expect = 0.66
Identities = 13/31 (41%), Positives = 22/31 (70%)
Query: 611 EIADKDSEDNWDEDEEESESEKDEDVEEEDE 641
E +D DSE+ DE+E++ + + D+D E+ DE
Sbjct: 508 EDSDSDSEEEDDEEEDDEDEDDDDDEEDGDE 538
Score = 33.5 bits (75), Expect = 0.66
Identities = 13/31 (41%), Positives = 22/31 (70%)
Query: 618 EDNWDEDEEESESEKDEDVEEEDEDAEGKDE 648
ED+ + EEE + E+D++ E++D+D E DE
Sbjct: 508 EDSDSDSEEEDDEEEDDEDEDDDDDEEDGDE 538
Score = 32.7 bits (73), Expect = 1.1
Identities = 13/32 (40%), Positives = 24/32 (75%), Gaps = 1/32 (3%)
Query: 622 DEDEEESESEKDEDVEEEDEDAEGKDEENGED 653
++ + +SE E DE+ ++EDED + DEE+G++
Sbjct: 508 EDSDSDSEEEDDEEEDDEDED-DDDDEEDGDE 538
>gi|115529449 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 55.8 bits (133), Expect = 1e-07
Identities = 32/99 (32%), Positives = 47/99 (47%), Gaps = 7/99 (7%)
Query: 582 SEKTKGATS---PGQKAKLVYEEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEE 638
S K K T P K+ + SE E DDE + ED+ DEDEEE + E + E+
Sbjct: 613 SNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDE----EDEDDEDEDEEEEDDENGDSSED 668
Query: 639 EDEDAEGKDEENGEDRDTASEKELNGDSDLDPENESEEE 677
+ +E E+ ED D E + + D D D + + + E
Sbjct: 669 GGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNE 707
Score = 55.8 bits (133), Expect = 1e-07
Identities = 28/78 (35%), Positives = 42/78 (53%), Gaps = 5/78 (6%)
Query: 600 EEESSEEESDDEIADK-----DSEDNWDEDEEESESEKDEDVEEEDEDAEGKDEENGEDR 654
+E+ EEE DDE D DS ++ EDE E E +ED E+ED+D + ++E+ E
Sbjct: 650 DEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESE 709
Query: 655 DTASEKELNGDSDLDPEN 672
++S +GDS N
Sbjct: 710 GSSSSSSSSGDSSDSDSN 727
Score = 52.4 bits (124), Expect = 1e-06
Identities = 31/85 (36%), Positives = 43/85 (50%), Gaps = 10/85 (11%)
Query: 601 EESSEEESDDEIADKD---------SEDNWDEDEEESESE-KDEDVEEEDEDAEGKDEEN 650
EE EE+ DDE D++ SED D E SE E +D D EED++ E DE++
Sbjct: 641 EEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDD 700
Query: 651 GEDRDTASEKELNGDSDLDPENESE 675
ED D SE + S ++S+
Sbjct: 701 DEDEDNESEGSSSSSSSSGDSSDSD 725
Score = 31.6 bits (70), Expect = 2.5
Identities = 15/62 (24%), Positives = 29/62 (46%)
Query: 582 SEKTKGATSPGQKAKLVYEEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDE 641
S + G +S + + +EE+ +DE D+D +++ D + E S S + D
Sbjct: 665 SSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDS 724
Query: 642 DA 643
D+
Sbjct: 725 DS 726
>gi|115529451 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 55.8 bits (133), Expect = 1e-07
Identities = 32/99 (32%), Positives = 47/99 (47%), Gaps = 7/99 (7%)
Query: 582 SEKTKGATS---PGQKAKLVYEEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEE 638
S K K T P K+ + SE E DDE + ED+ DEDEEE + E + E+
Sbjct: 613 SNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDE----EDEDDEDEDEEEEDDENGDSSED 668
Query: 639 EDEDAEGKDEENGEDRDTASEKELNGDSDLDPENESEEE 677
+ +E E+ ED D E + + D D D + + + E
Sbjct: 669 GGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNE 707
Score = 55.8 bits (133), Expect = 1e-07
Identities = 28/78 (35%), Positives = 42/78 (53%), Gaps = 5/78 (6%)
Query: 600 EEESSEEESDDEIADK-----DSEDNWDEDEEESESEKDEDVEEEDEDAEGKDEENGEDR 654
+E+ EEE DDE D DS ++ EDE E E +ED E+ED+D + ++E+ E
Sbjct: 650 DEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESE 709
Query: 655 DTASEKELNGDSDLDPEN 672
++S +GDS N
Sbjct: 710 GSSSSSSSSGDSSDSDSN 727
Score = 52.4 bits (124), Expect = 1e-06
Identities = 31/85 (36%), Positives = 43/85 (50%), Gaps = 10/85 (11%)
Query: 601 EESSEEESDDEIADKD---------SEDNWDEDEEESESE-KDEDVEEEDEDAEGKDEEN 650
EE EE+ DDE D++ SED D E SE E +D D EED++ E DE++
Sbjct: 641 EEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDD 700
Query: 651 GEDRDTASEKELNGDSDLDPENESE 675
ED D SE + S ++S+
Sbjct: 701 DEDEDNESEGSSSSSSSSGDSSDSD 725
Score = 31.6 bits (70), Expect = 2.5
Identities = 15/62 (24%), Positives = 29/62 (46%)
Query: 582 SEKTKGATSPGQKAKLVYEEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDE 641
S + G +S + + +EE+ +DE D+D +++ D + E S S + D
Sbjct: 665 SSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDS 724
Query: 642 DA 643
D+
Sbjct: 725 DS 726
>gi|7657671 upstream binding transcription factor, RNA polymerase I
isoform a [Homo sapiens]
Length = 764
Score = 55.8 bits (133), Expect = 1e-07
Identities = 32/99 (32%), Positives = 47/99 (47%), Gaps = 7/99 (7%)
Query: 582 SEKTKGATS---PGQKAKLVYEEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEE 638
S K K T P K+ + SE E DDE + ED+ DEDEEE + E + E+
Sbjct: 650 SNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDE----EDEDDEDEDEEEEDDENGDSSED 705
Query: 639 EDEDAEGKDEENGEDRDTASEKELNGDSDLDPENESEEE 677
+ +E E+ ED D E + + D D D + + + E
Sbjct: 706 GGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNE 744
Score = 55.8 bits (133), Expect = 1e-07
Identities = 28/78 (35%), Positives = 42/78 (53%), Gaps = 5/78 (6%)
Query: 600 EEESSEEESDDEIADK-----DSEDNWDEDEEESESEKDEDVEEEDEDAEGKDEENGEDR 654
+E+ EEE DDE D DS ++ EDE E E +ED E+ED+D + ++E+ E
Sbjct: 687 DEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESE 746
Query: 655 DTASEKELNGDSDLDPEN 672
++S +GDS N
Sbjct: 747 GSSSSSSSSGDSSDSDSN 764
Score = 52.4 bits (124), Expect = 1e-06
Identities = 31/85 (36%), Positives = 43/85 (50%), Gaps = 10/85 (11%)
Query: 601 EESSEEESDDEIADKD---------SEDNWDEDEEESESE-KDEDVEEEDEDAEGKDEEN 650
EE EE+ DDE D++ SED D E SE E +D D EED++ E DE++
Sbjct: 678 EEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDD 737
Query: 651 GEDRDTASEKELNGDSDLDPENESE 675
ED D SE + S ++S+
Sbjct: 738 DEDEDNESEGSSSSSSSSGDSSDSD 762
Score = 31.6 bits (70), Expect = 2.5
Identities = 15/62 (24%), Positives = 29/62 (46%)
Query: 582 SEKTKGATSPGQKAKLVYEEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDE 641
S + G +S + + +EE+ +DE D+D +++ D + E S S + D
Sbjct: 702 SSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDS 761
Query: 642 DA 643
D+
Sbjct: 762 DS 763
>gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens]
Length = 357
Score = 55.5 bits (132), Expect = 2e-07
Identities = 40/151 (26%), Positives = 66/151 (43%), Gaps = 20/151 (13%)
Query: 120 LISGGHDNRVNCIQWHQDSGCLYSCSDDKHIVEWNVQ-TCKVKCKWKGDNSSVSSLCISP 178
++ GH+ V C ++H + L S D+ I+ WNV C KG + +V L +
Sbjct: 60 MLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNT 119
Query: 179 DGKMLLSAG--RTIKLWVLETKEVYRHFTGHATPVSSLMFTTIRPPNESQPFDGITGLYF 236
DG ML SA +T+ +W ET E + GH + V+S + G
Sbjct: 120 DGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSC-------------YPARRGPQL 166
Query: 237 LSGAVHDRLLNVWQVRSENKEKSAVMSFTVT 267
+ D + +W +R +K+A+ +F T
Sbjct: 167 VCTGSDDGTVKLWDIR----KKAAIQTFQNT 193
Score = 44.7 bits (104), Expect = 3e-04
Identities = 50/213 (23%), Positives = 84/213 (39%), Gaps = 34/213 (15%)
Query: 106 ILLYSTVKGELHSKLISGGHDNRVNCIQWHQDSGCLYSCSDDKHIVEWNVQTCKVKCKWK 165
++L V G+ + GH V + ++ D L+S S DK + W+ +T + + K
Sbjct: 89 LILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSMLFSASTDKTVAVWDSETGERVKRLK 148
Query: 166 GDNSSVSSLCISPDGKMLLSAGR---TIKLWVLETKEVYRHFTGHATPVSSLMFTTIRPP 222
G S V+S + G L+ G T+KLW + K + F + V ++ F
Sbjct: 149 GHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAIQTFQ-NTYQVLAVTFND---- 203
Query: 223 NESQPFDGITGLYFLSGAVHDRLLNVWQVRSENK-------EKSAVMSFTVTDEPVYIDL 275
T +SG + D + VW +R +NK +V +++ E Y+
Sbjct: 204 ---------TSDQIISGGI-DNDIKVWDLR-QNKLTYTMRGHADSVTGLSLSSEGSYLLS 252
Query: 276 TLSENKEE--------PVKLAVVCRDGQVHLFE 300
+N P + V G VH FE
Sbjct: 253 NAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFE 285
Score = 32.3 bits (72), Expect = 1.5
Identities = 16/70 (22%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
Query: 127 NRVNCIQWHQDSGCLYSCSDDKHIVEWNVQTCKVKCKWKGDNSSVSSLCISPDGKMLLSA 186
N + C W D + + S D+ + W+ + ++ K G S++ + PD +++SA
Sbjct: 287 NLLRC-SWSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDEPIIISA 345
Query: 187 GRTIKLWVLE 196
+L++ E
Sbjct: 346 SSDKRLYMGE 355
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 54.7 bits (130), Expect = 3e-07
Identities = 26/77 (33%), Positives = 51/77 (66%), Gaps = 2/77 (2%)
Query: 601 EESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDEDAEGKDEENGEDRDTASEK 660
+E+ EEE ++E +++ E++ +E+EEE ESE E EE+++ ++ KD +G+ D K
Sbjct: 528 KENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKD--SGKTLDKKPSK 585
Query: 661 ELNGDSDLDPENESEEE 677
E++ DS+ D +++ +E
Sbjct: 586 EMSSDSEYDSDDDRTKE 602
Score = 43.5 bits (101), Expect = 6e-04
Identities = 25/76 (32%), Positives = 42/76 (55%), Gaps = 3/76 (3%)
Query: 605 EEESDDEIADKDSEDNWDEDEEESESEKDE---DVEEEDEDAEGKDEENGEDRDTASEKE 661
EEE D E A D + DEE + E ++ +V+E E+ E ++EE ED ++ E+E
Sbjct: 493 EEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEE 552
Query: 662 LNGDSDLDPENESEEE 677
G+S+ +E +E+
Sbjct: 553 EEGESEGSEGDEEDEK 568
Score = 35.8 bits (81), Expect = 0.13
Identities = 26/101 (25%), Positives = 49/101 (48%), Gaps = 12/101 (11%)
Query: 585 TKGATSPGQKAKLVYEEESSEEESDDEIADKDSEDNWDED---EEESESEKDEDVEEEDE 641
+K GQK K ++S ++ +E+ DKDS+ E S S+ D+D + +
Sbjct: 93 SKDKKKKGQKGK----KQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPK 148
Query: 642 DAEGKDEE-----NGEDRDTASEKELNGDSDLDPENESEEE 677
A+GK ++ +G + D + K++ S ++ ES +E
Sbjct: 149 KAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDE 189
Score = 31.6 bits (70), Expect = 2.5
Identities = 24/91 (26%), Positives = 45/91 (49%), Gaps = 9/91 (9%)
Query: 593 QKAKLV--YEEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDV----EEEDEDAEGK 646
+KAKL E+E E D+ K+S+ ++E+ +S+ D V EE+ E
Sbjct: 246 EKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAA 305
Query: 647 DEENGEDRDTASEKELNGDSDLDPENESEEE 677
+++N D+ +K+ G+ + E E E++
Sbjct: 306 EDDNEGDKKKKDKKKKKGEKE---EKEKEKK 333
Score = 30.8 bits (68), Expect = 4.3
Identities = 20/76 (26%), Positives = 39/76 (51%), Gaps = 6/76 (7%)
Query: 583 EKTKGATSPGQKA------KLVYEEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDV 636
EK KG + KA KL EEE + E ++ I + + ++EE E EK E
Sbjct: 331 EKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERK 390
Query: 637 EEEDEDAEGKDEENGE 652
++++++ + + ++ G+
Sbjct: 391 KQKEKERKERLKKEGK 406
>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
Length = 709
Score = 54.7 bits (130), Expect = 3e-07
Identities = 28/69 (40%), Positives = 41/69 (59%), Gaps = 2/69 (2%)
Query: 600 EEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDEDAEGKDEENGEDRDTASE 659
+EE E+ +DE D+D E+ +E+EEE E E++E+ EEE E E +E G D DT SE
Sbjct: 212 DEEVEEDAEEDEEVDEDGEE--EEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSE 269
Query: 660 KELNGDSDL 668
+G +
Sbjct: 270 ASDSGSESV 278
Score = 50.4 bits (119), Expect = 5e-06
Identities = 26/72 (36%), Positives = 44/72 (61%), Gaps = 3/72 (4%)
Query: 600 EEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDEDAEGKDEENGEDRDTASE 659
EEE EE+ ++ D++ E++ +EDEE E ++E+ EEE+E+ E ++EE ++D +
Sbjct: 201 EEEGVEEDVEE---DEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQ 257
Query: 660 KELNGDSDLDPE 671
KE D D E
Sbjct: 258 KEEGNDYDTRSE 269
Score = 48.1 bits (113), Expect = 3e-05
Identities = 32/95 (33%), Positives = 46/95 (48%), Gaps = 4/95 (4%)
Query: 583 EKTKGATSPGQKAKLVYEEESSEEE-SDDEIADKDSEDNWDEDEEESESEKDEDVEEEDE 641
E + A+ Q +K EE +SEE SD E S D + E E +EDVEE++E
Sbjct: 158 EVDRRASRSSQSSK---EEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEE 214
Query: 642 DAEGKDEENGEDRDTASEKELNGDSDLDPENESEE 676
E +E+ D D E+E + + + E E EE
Sbjct: 215 VEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEE 249
Score = 48.1 bits (113), Expect = 3e-05
Identities = 27/101 (26%), Positives = 55/101 (54%), Gaps = 7/101 (6%)
Query: 583 EKTKGATSPGQKAKLVYEEESSEEE------SDDEIADKDSEDNWDEDEEESESEKDEDV 636
++ +S K ++ EE S+ E SD++ + ++E+ E++ E + E +ED
Sbjct: 160 DRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDA 219
Query: 637 EEEDE-DAEGKDEENGEDRDTASEKELNGDSDLDPENESEE 676
EE++E D +G++EE E+ + E+E + + D ++ EE
Sbjct: 220 EEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEE 260
Score = 48.1 bits (113), Expect = 3e-05
Identities = 26/85 (30%), Positives = 46/85 (54%), Gaps = 7/85 (8%)
Query: 600 EEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDEDAEGKD-EENGEDRDTAS 658
EE++ E+E DE +++ E+ +E+EEE E E++ + +E D+ EG D + E D+ S
Sbjct: 216 EEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGS 275
Query: 659 EK------ELNGDSDLDPENESEEE 677
E + S D +E ++E
Sbjct: 276 ESVSFTDGSVRSGSGTDGSDEKKKE 300
Score = 45.8 bits (107), Expect = 1e-04
Identities = 22/73 (30%), Positives = 40/73 (54%)
Query: 604 SEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDEDAEGKDEENGEDRDTASEKELN 663
+EEE +E ++D E D +E+E E E+ EEE+E+ E ++EE E+ + +
Sbjct: 200 NEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKE 259
Query: 664 GDSDLDPENESEE 676
+D D +E+ +
Sbjct: 260 EGNDYDTRSEASD 272
Score = 42.4 bits (98), Expect = 0.001
Identities = 24/75 (32%), Positives = 44/75 (58%), Gaps = 4/75 (5%)
Query: 603 SSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDEDAEGKDEENGEDRDTASEKEL 662
SS+E+ ++ +++ + E++EE E + +ED EE DED E ++EE E+ + E+E
Sbjct: 190 SSDEQGNNTENEEEGVEEDVEEDEEVEEDAEED-EEVDEDGEEEEEEEEEEEEEEEEEEE 248
Query: 663 NGDSDLDPENESEEE 677
+ D E + +EE
Sbjct: 249 EYEQD---ERDQKEE 260
Score = 39.7 bits (91), Expect = 0.009
Identities = 23/94 (24%), Positives = 40/94 (42%)
Query: 584 KTKGATSPGQKAKLVYEEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDEDA 643
+ K T G + + + + S + +SE+ + E S DE + +
Sbjct: 143 RAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEE 202
Query: 644 EGKDEENGEDRDTASEKELNGDSDLDPENESEEE 677
EG +E+ ED + + E + + D D E E EEE
Sbjct: 203 EGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEE 236
>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
Length = 727
Score = 54.7 bits (130), Expect = 3e-07
Identities = 28/69 (40%), Positives = 41/69 (59%), Gaps = 2/69 (2%)
Query: 600 EEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDEDAEGKDEENGEDRDTASE 659
+EE E+ +DE D+D E+ +E+EEE E E++E+ EEE E E +E G D DT SE
Sbjct: 212 DEEVEEDAEEDEEVDEDGEE--EEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSE 269
Query: 660 KELNGDSDL 668
+G +
Sbjct: 270 ASDSGSESV 278
Score = 50.4 bits (119), Expect = 5e-06
Identities = 26/72 (36%), Positives = 44/72 (61%), Gaps = 3/72 (4%)
Query: 600 EEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDEDAEGKDEENGEDRDTASE 659
EEE EE+ ++ D++ E++ +EDEE E ++E+ EEE+E+ E ++EE ++D +
Sbjct: 201 EEEGVEEDVEE---DEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQ 257
Query: 660 KELNGDSDLDPE 671
KE D D E
Sbjct: 258 KEEGNDYDTRSE 269
Score = 48.1 bits (113), Expect = 3e-05
Identities = 32/95 (33%), Positives = 46/95 (48%), Gaps = 4/95 (4%)
Query: 583 EKTKGATSPGQKAKLVYEEESSEEE-SDDEIADKDSEDNWDEDEEESESEKDEDVEEEDE 641
E + A+ Q +K EE +SEE SD E S D + E E +EDVEE++E
Sbjct: 158 EVDRRASRSSQSSK---EEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEE 214
Query: 642 DAEGKDEENGEDRDTASEKELNGDSDLDPENESEE 676
E +E+ D D E+E + + + E E EE
Sbjct: 215 VEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEE 249
Score = 48.1 bits (113), Expect = 3e-05
Identities = 27/101 (26%), Positives = 55/101 (54%), Gaps = 7/101 (6%)
Query: 583 EKTKGATSPGQKAKLVYEEESSEEE------SDDEIADKDSEDNWDEDEEESESEKDEDV 636
++ +S K ++ EE S+ E SD++ + ++E+ E++ E + E +ED
Sbjct: 160 DRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDA 219
Query: 637 EEEDE-DAEGKDEENGEDRDTASEKELNGDSDLDPENESEE 676
EE++E D +G++EE E+ + E+E + + D ++ EE
Sbjct: 220 EEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEE 260
Score = 48.1 bits (113), Expect = 3e-05
Identities = 26/85 (30%), Positives = 46/85 (54%), Gaps = 7/85 (8%)
Query: 600 EEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDEDAEGKD-EENGEDRDTAS 658
EE++ E+E DE +++ E+ +E+EEE E E++ + +E D+ EG D + E D+ S
Sbjct: 216 EEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGS 275
Query: 659 EK------ELNGDSDLDPENESEEE 677
E + S D +E ++E
Sbjct: 276 ESVSFTDGSVRSGSGTDGSDEKKKE 300
Score = 45.8 bits (107), Expect = 1e-04
Identities = 22/73 (30%), Positives = 40/73 (54%)
Query: 604 SEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDEDAEGKDEENGEDRDTASEKELN 663
+EEE +E ++D E D +E+E E E+ EEE+E+ E ++EE E+ + +
Sbjct: 200 NEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKE 259
Query: 664 GDSDLDPENESEE 676
+D D +E+ +
Sbjct: 260 EGNDYDTRSEASD 272
Score = 42.4 bits (98), Expect = 0.001
Identities = 24/75 (32%), Positives = 44/75 (58%), Gaps = 4/75 (5%)
Query: 603 SSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDEDAEGKDEENGEDRDTASEKEL 662
SS+E+ ++ +++ + E++EE E + +ED EE DED E ++EE E+ + E+E
Sbjct: 190 SSDEQGNNTENEEEGVEEDVEEDEEVEEDAEED-EEVDEDGEEEEEEEEEEEEEEEEEEE 248
Query: 663 NGDSDLDPENESEEE 677
+ D E + +EE
Sbjct: 249 EYEQD---ERDQKEE 260
Score = 39.7 bits (91), Expect = 0.009
Identities = 23/94 (24%), Positives = 40/94 (42%)
Query: 584 KTKGATSPGQKAKLVYEEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDEDA 643
+ K T G + + + + S + +SE+ + E S DE + +
Sbjct: 143 RAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEE 202
Query: 644 EGKDEENGEDRDTASEKELNGDSDLDPENESEEE 677
EG +E+ ED + + E + + D D E E EEE
Sbjct: 203 EGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEE 236
>gi|169210053 PREDICTED: hypothetical protein [Homo sapiens]
Length = 185
Score = 54.3 bits (129), Expect = 4e-07
Identities = 27/61 (44%), Positives = 39/61 (63%)
Query: 593 QKAKLVYEEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDEDAEGKDEENGE 652
Q+ V EEE EEE + E +K+ E DE+EEE E EK+ED EEE+++ + +EE E
Sbjct: 113 QQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVE 172
Query: 653 D 653
+
Sbjct: 173 E 173
Score = 47.4 bits (111), Expect = 4e-05
Identities = 26/82 (31%), Positives = 49/82 (59%), Gaps = 1/82 (1%)
Query: 590 SPGQKAKLVYEEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVEEEDEDAEGKDEE 649
S + A LV EE S+++ E + + E+ + +EEE E EK+ED EEE+++ E +++E
Sbjct: 98 SVARTAALVAEECSAQQGLPVEEEEVEEEEE-EVEEEEKEEEKEEDEEEEEKEEEKEEDE 156
Query: 650 NGEDRDTASEKELNGDSDLDPE 671
E+++ +E + ++D E
Sbjct: 157 EEEEKEGKKMEEEKVEEEIDTE 178
Score = 37.4 bits (85), Expect = 0.046
Identities = 19/56 (33%), Positives = 31/56 (55%)
Query: 622 DEDEEESESEKDEDVEEEDEDAEGKDEENGEDRDTASEKELNGDSDLDPENESEEE 677
+E+E E E E+ E+ E+E+E E ++EE E+ E+E + E + EEE
Sbjct: 119 EEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEE 174
Score = 30.4 bits (67), Expect = 5.6
Identities = 15/52 (28%), Positives = 27/52 (51%)
Query: 626 EESESEKDEDVEEEDEDAEGKDEENGEDRDTASEKELNGDSDLDPENESEEE 677
EE +++ VEEE+ + E ++ E E + E E + + + E + EEE
Sbjct: 108 EECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEE 159
>gi|4759276 RNA, U3 small nucleolar interacting protein 2 [Homo
sapiens]
Length = 475
Score = 53.9 bits (128), Expect = 5e-07
Identities = 39/141 (27%), Positives = 60/141 (42%), Gaps = 27/141 (19%)
Query: 124 GHDNRVNCIQWHQDSGCLYSCSDDKHIVEWNVQTCK-----------VKCKWKGDNSSVS 172
GH + C+ D ++S + D I++W+V++ + + K G +S V
Sbjct: 144 GHQLSITCLVVTPDDSAIFSAAKDCSIIKWSVESGRKLHVIPRAKKGAEGKPPGHSSHVL 203
Query: 173 SLCISPDGKMLLSAGRT--IKLWVLETKEVYRHFTGHATPVSSLMFTTIRPPNESQPFDG 230
+ IS DGK L S R+ I +W ++ + FTGH VS L F
Sbjct: 204 CMAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFR------------- 250
Query: 231 ITGLYFLSGAVHDRLLNVWQV 251
G + L HDR + VW V
Sbjct: 251 -RGTHQLYSTSHDRSVKVWNV 270
Score = 39.7 bits (91), Expect = 0.009
Identities = 30/135 (22%), Positives = 52/135 (38%), Gaps = 16/135 (11%)
Query: 124 GHDNRVNCIQWHQDSGCLYSCSDDKHIVEWNVQTCKVKCKWKGDNSSVSSLCISPDGKML 183
GH + V C+ D L S K I+ W Q+C+ + G +VS L L
Sbjct: 197 GHSSHVLCMAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRRGTHQL 256
Query: 184 LSAG--RTIKLWVLETKEVYRHFTGHATPVSSLMFTTIRPPNESQPFDGITGLYFLSGAV 241
S R++K+W + GH V++L D ++ ++
Sbjct: 257 YSTSHDRSVKVWNVAENSYVETLFGHQDAVAAL--------------DALSRECCVTAGG 302
Query: 242 HDRLLNVWQVRSENK 256
D + VW++ E++
Sbjct: 303 RDGTVRVWKIPEESQ 317
>gi|21071067 TBP-associated factor 5 [Homo sapiens]
Length = 800
Score = 53.9 bits (128), Expect = 5e-07
Identities = 56/206 (27%), Positives = 86/206 (41%), Gaps = 27/206 (13%)
Query: 124 GHDNRVNCIQWHQDSGCLYSCSDDKHIVEWNVQTCKVKCKWKGDNSSVSSLCISPDGKML 183
GH V + D L S S+D + W++QT +KG N V SP G
Sbjct: 541 GHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYF 600
Query: 184 LSAG--RTIKLWVLETKEVYRHFTGHATPVSSLMFTTIRPPNESQPFDGITGLYFLSGAV 241
+S G R +LW + + R F GH V+ F PN + Y +G+
Sbjct: 601 VSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRF----HPNSN---------YVATGSA 647
Query: 242 HDRLLNVWQVRSENKEKSAVMSFTVTDEPVYIDLTLSENKEEPVKLAVVCRDGQVHLFE- 300
DR + +W V + N V FT P++ LT S N LA DG+V L++
Sbjct: 648 -DRTVRLWDVLNGN----CVRIFTGHKGPIH-SLTFSPNGR---FLATGATDGRVLLWDI 698
Query: 301 --HILNGYCKKPLTSNCTIQIATPGK 324
++ G K + C+++ + G+
Sbjct: 699 GHGLMVGELKGHTDTVCSLRFSRDGE 724
Score = 42.0 bits (97), Expect = 0.002
Identities = 29/100 (29%), Positives = 46/100 (46%), Gaps = 4/100 (4%)
Query: 121 ISGGHDNRVNCIQWHQDSGCLYSCSDDKHIVEWNVQTCKVKCKWKGDNSSVSSLCISPDG 180
I GH VNC ++H +S + + S D+ + W+V + G + SL SP+G
Sbjct: 622 IFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNG 681
Query: 181 KMLLSA---GRTIKLWVLETKEVYRHFTGHATPVSSLMFT 217
+ L + GR + LW + + GH V SL F+
Sbjct: 682 RFLATGATDGRVL-LWDIGHGLMVGELKGHTDTVCSLRFS 720
Score = 36.2 bits (82), Expect = 0.10
Identities = 36/171 (21%), Positives = 67/171 (39%), Gaps = 8/171 (4%)
Query: 26 QAYFALASTDGH-LRVWETANNRLHQEYVPSAHLSGTCTCLAWAPARLQAKESPQRKKRK 84
Q + L GH VW+T + +V H WA Q
Sbjct: 573 QTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGH---DRVARLWATDHYQPLRIFAGHLAD 629
Query: 85 SEAVGMSNQTDLLALGTAVGSILLYSTVKGELHSKLISGGHDNRVNCIQWHQDSGCLYSC 144
++ +A G+A ++ L+ + G + I GH ++ + + + L +
Sbjct: 630 VNCTRFHPNSNYVATGSADRTVRLWDVLNG--NCVRIFTGHKGPIHSLTFSPNGRFLATG 687
Query: 145 SDDKHIVEWNVQTCKVKCKWKGDNSSVSSLCISPDGKMLLSAG--RTIKLW 193
+ D ++ W++ + + KG +V SL S DG++L S T++LW
Sbjct: 688 ATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLW 738
>gi|5803221 WD repeat-containing protein 3 [Homo sapiens]
Length = 943
Score = 53.1 bits (126), Expect = 8e-07
Identities = 33/121 (27%), Positives = 60/121 (49%), Gaps = 4/121 (3%)
Query: 97 LALGTAVGSILLYSTVKGELHSKLISGGHDNRVNCIQWHQDSGCLYSCSDDKHIVEWNVQ 156
LA+G GSI ++S + GE + GH + +++ Q G L S S D I+ W+V
Sbjct: 80 LAVGYEDGSIRIFSLLSGE--GNVTFNGHKAAITTLKYDQLGGRLASGSKDTDIIVWDVI 137
Query: 157 TCKVKCKWKGDNSSVSSLCISPDGKMLLSAGR--TIKLWVLETKEVYRHFTGHATPVSSL 214
+ KG +++ + +L+++G+ +K W L+T+ ++ GH T V L
Sbjct: 138 NESGLYRLKGHKDAITQALFLREKNLLVTSGKDTMVKWWDLDTQHCFKTMVGHRTEVWGL 197
Query: 215 M 215
+
Sbjct: 198 V 198
Score = 40.8 bits (94), Expect = 0.004
Identities = 24/106 (22%), Positives = 53/106 (50%), Gaps = 4/106 (3%)
Query: 90 MSNQTDLLALGTAVGSILLYSTVKGELHSKLISGGHDNRVNCIQWHQDSGCLYSCSDDKH 149
+S+ L+A G+A ++ ++ G+ H L + HD+ V +Q+ S ++ D
Sbjct: 599 ISHDGALIATGSADRNVKIWGLDFGDCHKSLFA--HDDSVMYLQFVPKSHLFFTAGKDHK 656
Query: 150 IVEWNVQTCKVKCKWKGDNSSVSSLCISPDGKMLLSAG--RTIKLW 193
I +W+ + +G + + L +SP G ++S+ ++++LW
Sbjct: 657 IKQWDADKFEHIQTLEGHHQEIWCLAVSPSGDYVVSSSHDKSLRLW 702
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 52.8 bits (125), Expect = 1e-06
Identities = 29/92 (31%), Positives = 46/92 (50%), Gaps = 17/92 (18%)
Query: 600 EEESSEEESDDEIADKDSEDNWDEDEEESESEK-----------------DEDVEEEDED 642
E+E E++ DDE D D ED+ +E+ E+ K DED EE+DED
Sbjct: 185 EDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDED 244
Query: 643 AEGKDEENGEDRDTASEKELNGDSDLDPENES 674
+ D+E+ ED D ++E + + +P E+
Sbjct: 245 EDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEA 276
Score = 51.6 bits (122), Expect = 2e-06
Identities = 29/82 (35%), Positives = 47/82 (57%), Gaps = 1/82 (1%)
Query: 578 QVTASEKTKGATSPGQKAKLVYEEESSEEESDDEIADKDSEDNWDEDEEESESEKDEDVE 637
+ T ++ K A KAK V E+E EE+ +DE D D +D D+DE++ E E++E+ E
Sbjct: 212 ETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEE-E 270
Query: 638 EEDEDAEGKDEENGEDRDTASE 659
E ++A GK ++ + A E
Sbjct: 271 EPVKEAPGKRKKEMAKQKAAPE 292
Score = 50.1 bits (118), Expect = 7e-06
Identities = 43/151 (28%), Positives = 65/151 (43%), Gaps = 52/151 (34%)
Query: 579 VTASEKTKGATSPGQKAKL----------VYEEESSEE-ESDDEIADKDSED-------- 619
+ A+ KGA P + AK E++ SEE E DDE D+D ++
Sbjct: 118 LVATPGKKGAAIPAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKA 177
Query: 620 ------NWDEDEEESESEKDEDVEEEDED---------AEGK------------------ 646
+ DED+E+ E ++D+D +EED+ A+GK
Sbjct: 178 AAAAPASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDED 237
Query: 647 DEENGEDRDTASEKELNGDSDLDPENESEEE 677
+EE+ ED D +++ D D D E E EEE
Sbjct: 238 EEEDDEDEDDDDDEDDEDDDDEDDEEEEEEE 268
Score = 45.4 bits (106), Expect = 2e-04
Identities = 27/94 (28%), Positives = 46/94 (48%), Gaps = 21/94 (22%)
Query: 588 ATSPGQKAKLVYEEESSEEESDDEIADKDSE--------------------DNWDEDEEE 627
A +P + + ++E E++ DDE D + E N EDE+E
Sbjct: 179 AAAPASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDE 238
Query: 628 SESEKDEDVEEEDEDAEGKDEENGEDRDTASEKE 661
E ++DED +++DED E D+E+ E+ + E+E
Sbjct: 239 EEDDEDED-DDDDEDDEDDDDEDDEEEEEEEEEE 271
>gi|156071450 nardilysin isoform a [Homo sapiens]
Length = 1219
Score = 52.4 bits (124), Expect = 1e-06
Identities = 31/102 (30%), Positives = 56/102 (54%), Gaps = 2/102 (1%)
Query: 560 KTFQKLSHLHGKLILLITQVTASEKTKGATSPGQKAKLVYEEESSEEESDDEIADKDSED 619
K ++ + +G LLI+ ++ E G T+ ++ + V EEE ++E + D E+
Sbjct: 111 KQYRYIKLQNGLQALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEE 170
Query: 620 NWDEDEEESESEKDEDVEEEDEDAEGKDEENGEDRDTASEKE 661
+D DE+E + E D+D++ ED + E + EE E R +EK+
Sbjct: 171 GFD-DEDEFDDEHDDDLDTEDNELE-ELEERAEARKKTTEKQ 210
Score = 43.1 bits (100), Expect = 8e-04
Identities = 22/56 (39%), Positives = 32/56 (57%), Gaps = 3/56 (5%)
Query: 622 DEDEEESESEKDEDVEEEDEDAEGKDEENGEDRDTASEKELNGDSDLDPENESEEE 677
DE+EEE E E+++D E+ + E DEE +D D ++ D DLD E+ EE
Sbjct: 143 DEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEH---DDDLDTEDNELEE 195
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.130 0.384
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,252,384
Number of Sequences: 37866
Number of extensions: 1408246
Number of successful extensions: 33202
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 733
Number of HSP's successfully gapped in prelim test: 488
Number of HSP's that attempted gapping in prelim test: 9735
Number of HSP's gapped (non-prelim): 10919
length of query: 677
length of database: 18,247,518
effective HSP length: 109
effective length of query: 568
effective length of database: 14,120,124
effective search space: 8020230432
effective search space used: 8020230432
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.