Search of human proteins with 157426898

Search of human proteins with 157426898

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|157426898 tripartite motif-containing 10 isoform 1 [Homo
sapiens]
         (481 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|157426898 tripartite motif-containing 10 isoform 1 [Homo sapi...   984   0.0  
gi|157426896 tripartite motif-containing 10 isoform 2 [Homo sapi...   758   0.0  
gi|149193331 tripartite motif protein 15 [Homo sapiens]               387   e-107
gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]   315   6e-86
gi|4508005 tripartite motif-containing 26 [Homo sapiens]              303   2e-82
gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]   300   1e-81
gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens]    280   3e-75
gi|37622899 ring finger protein 137 [Homo sapiens]                    278   8e-75
gi|5730009 ret finger protein [Homo sapiens]                          276   4e-74
gi|112421127 tripartite motif-containing 58 [Homo sapiens]            261   1e-69
gi|157743261 tripartite motif-containing 75 [Homo sapiens]            242   6e-64
gi|5454014 tripartite motif-containing 38 [Homo sapiens]              240   2e-63
gi|15208660 tripartite motif protein 21 [Homo sapiens]                228   7e-60
gi|21630277 tripartite motif-containing 11 [Homo sapiens]             225   6e-59
gi|22749269 ring finger protein 129 [Homo sapiens]                    213   4e-55
gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo sa...   211   2e-54
gi|42516572 tripartite motif-containing 41 isoform 1 [Homo sapiens]   205   6e-53
gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo s...   197   2e-50
gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens]    194   1e-49
gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens]    194   1e-49
gi|4557743 Mediterranean fever protein [Homo sapiens]                 189   5e-48
gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens]   186   3e-47
gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens]    186   3e-47
gi|88999601 tripartite motif-containing 69 isoform a [Homo sapiens]   185   9e-47
gi|62865604 tripartite motif protein 31 [Homo sapiens]                177   2e-44
gi|42516574 tripartite motif-containing 41 isoform 2 [Homo sapiens]   176   4e-44
gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens]      173   3e-43
gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens]      173   3e-43
gi|51477690 tripartite motif-containing 6 and tripartite motif-c...   173   3e-43
gi|117938316 tripartite motif-containing 22 [Homo sapiens]            173   4e-43

>gi|157426898 tripartite motif-containing 10 isoform 1 [Homo
           sapiens]
          Length = 481

 Score =  984 bits (2545), Expect = 0.0
 Identities = 481/481 (100%), Positives = 481/481 (100%)

Query: 1   MASAASVTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLC 60
           MASAASVTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLC
Sbjct: 1   MASAASVTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLC 60

Query: 61  KEPFRPGSFRPNWQLANVVENIERLQLVSTLGLGEEDVCQEHGEKIYFFCEDDEMQLCVV 120
           KEPFRPGSFRPNWQLANVVENIERLQLVSTLGLGEEDVCQEHGEKIYFFCEDDEMQLCVV
Sbjct: 61  KEPFRPGSFRPNWQLANVVENIERLQLVSTLGLGEEDVCQEHGEKIYFFCEDDEMQLCVV 120

Query: 121 CREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQVLLTQVST 180
           CREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQVLLTQVST
Sbjct: 121 CREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQVLLTQVST 180

Query: 181 KRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFSALIEELE 240
           KRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFSALIEELE
Sbjct: 181 KRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFSALIEELE 240

Query: 241 EKNERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPLQREMKMFLEK 300
           EKNERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPLQREMKMFLEK
Sbjct: 241 EKNERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPLQREMKMFLEK 300

Query: 301 LCFELDYEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDRATCVLAHTGI 360
           LCFELDYEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDRATCVLAHTGI
Sbjct: 301 LCFELDYEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDRATCVLAHTGI 360

Query: 361 TGGRHTWVVSIDLAHGGSCTVGVVSEDVQRKGELRLRPEEGVWAVRLAWGFVSALGSFPT 420
           TGGRHTWVVSIDLAHGGSCTVGVVSEDVQRKGELRLRPEEGVWAVRLAWGFVSALGSFPT
Sbjct: 361 TGGRHTWVVSIDLAHGGSCTVGVVSEDVQRKGELRLRPEEGVWAVRLAWGFVSALGSFPT 420

Query: 421 RLTLKEQPRQVRVSLDYEVGWVTFTNAVTREPIYTFTASFTRKVIPFFGLWGRGSSFSLS 480
           RLTLKEQPRQVRVSLDYEVGWVTFTNAVTREPIYTFTASFTRKVIPFFGLWGRGSSFSLS
Sbjct: 421 RLTLKEQPRQVRVSLDYEVGWVTFTNAVTREPIYTFTASFTRKVIPFFGLWGRGSSFSLS 480

Query: 481 S 481
           S
Sbjct: 481 S 481


>gi|157426896 tripartite motif-containing 10 isoform 2 [Homo
           sapiens]
          Length = 395

 Score =  758 bits (1957), Expect = 0.0
 Identities = 368/368 (100%), Positives = 368/368 (100%)

Query: 1   MASAASVTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLC 60
           MASAASVTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLC
Sbjct: 1   MASAASVTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLC 60

Query: 61  KEPFRPGSFRPNWQLANVVENIERLQLVSTLGLGEEDVCQEHGEKIYFFCEDDEMQLCVV 120
           KEPFRPGSFRPNWQLANVVENIERLQLVSTLGLGEEDVCQEHGEKIYFFCEDDEMQLCVV
Sbjct: 61  KEPFRPGSFRPNWQLANVVENIERLQLVSTLGLGEEDVCQEHGEKIYFFCEDDEMQLCVV 120

Query: 121 CREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQVLLTQVST 180
           CREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQVLLTQVST
Sbjct: 121 CREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQVLLTQVST 180

Query: 181 KRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFSALIEELE 240
           KRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFSALIEELE
Sbjct: 181 KRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFSALIEELE 240

Query: 241 EKNERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPLQREMKMFLEK 300
           EKNERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPLQREMKMFLEK
Sbjct: 241 EKNERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPLQREMKMFLEK 300

Query: 301 LCFELDYEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDRATCVLAHTGI 360
           LCFELDYEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDRATCVLAHTGI
Sbjct: 301 LCFELDYEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDRATCVLAHTGI 360

Query: 361 TGGRHTWV 368
           TGGRHTWV
Sbjct: 361 TGGRHTWV 368


>gi|149193331 tripartite motif protein 15 [Homo sapiens]
          Length = 465

 Score =  387 bits (994), Expect = e-107
 Identities = 203/464 (43%), Positives = 284/464 (61%), Gaps = 16/464 (3%)

Query: 16  CPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLCKEPFRPGSFRPNWQL 75
           C +C G L + VTI CGH FCR CL    ++      +   CPLC+E             
Sbjct: 16  CTLCAGPLEDAVTIPCGHTFCRLCLPALSQMGAQSSGKILLCPLCQEE------------ 63

Query: 76  ANVVENIERLQLVSTLGLGEEDVCQEHGEKIYFFCEDDEMQLCVVCREAGEHATHTMRFL 135
               E  E       LG   E  C+EHGEKIYFFCE+D   LCV CRE   H  HT+ FL
Sbjct: 64  ----EQAETPMAPVPLGPLGETYCEEHGEKIYFFCENDAEFLCVFCREGPTHQAHTVGFL 119

Query: 136 EDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQVLLTQVSTKRQQVISEFAHLRKF 195
           ++A  PYR+++   L+ L  ER+EI++++ +E++++QVLLTQ+ +K+ QV + F  L++ 
Sbjct: 120 DEAIQPYRDRLRSRLEALSTERDEIEDVKCQEDQKLQVLLTQIESKKHQVETAFERLQQE 179

Query: 196 LEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFSALIEELEEKNERPARELLTDIR 255
           LE+Q+ +LLA+L   +  I ++RDE+   V+ E+ R  A ++ELEEK ++PA ELL D+R
Sbjct: 180 LEQQRCLLLARLRELEQQIWKERDEYITKVSEEVTRLGAQVKELEEKCQQPASELLQDVR 239

Query: 256 STLIRCETRKCRKPVAVSPELGQRIRDFPQQALPLQREMKMFLEKLCFELDYEPAHISLD 315
               RCE +    P A+SP+L ++IRDF ++ L L   M+MF E L   L+ +   I+LD
Sbjct: 240 VNQSRCEMKTFVSPEAISPDLVKKIRDFHRKILTLPEMMRMFSENLAHHLEIDSGVITLD 299

Query: 316 PQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDRATCVLAHTGITGGRHTWVVSIDLAH 375
           PQT+   L+LSED +  +++ + ++ PD+P RFD    VL   G + GRH W V + L  
Sbjct: 300 PQTASRSLVLSEDRKSVRYTRQKKSLPDSPLRFDGLPAVLGFPGFSSGRHRWQVDLQLGD 359

Query: 376 GGSCTVGVVSEDVQRKGELRLRPEEGVWAVRLAWGFVSALGSFPTRLTLKEQPRQVRVSL 435
           GG CTVGV  E V+RKGE+ L  E+GVWAV ++     A  S  T L L E PR VRV+L
Sbjct: 360 GGGCTVGVAGEGVRRKGEMGLSAEDGVWAVIISHQQCWASTSPGTDLPLSEIPRGVRVAL 419

Query: 436 DYEVGWVTFTNAVTREPIYTFTASFTRKVIPFFGLWGRGSSFSL 479
           DYE G VT  NA T+EPI+TFTASF+ KV PFF +W +GS  +L
Sbjct: 420 DYEAGQVTLHNAQTQEPIFTFTASFSGKVFPFFAVWKKGSCLTL 463


>gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]
          Length = 488

 Score =  315 bits (807), Expect = 6e-86
 Identities = 180/470 (38%), Positives = 276/470 (58%), Gaps = 22/470 (4%)

Query: 2   ASAASVTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLCK 61
           ++AA++ +L  E +C +C   L+EPV I+CGHNFC+AC+TR+ E    DLE    CP+C+
Sbjct: 15  STAAALENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWE----DLERDFPCPVCR 70

Query: 62  EPFRPGSFRPNWQLANVVENIERLQLVSTLGLGEEDVCQEHGEKIYFFCEDDEMQLCVVC 121
           +  R  S RPN QL ++VE  ++LQ V    + +E +C +H E +  FC +D+  +C++C
Sbjct: 71  KTSRYRSLRPNRQLGSMVEIAKQLQAVKRK-IRDESLCPQHHEALSLFCYEDQEAVCLIC 129

Query: 122 REAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQVLLTQVSTK 181
             +  H  HT+  L+DA   Y+E++ KCL+ L ++ +EI   +S E K+   L   V ++
Sbjct: 130 AISHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVESR 189

Query: 182 RQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFSALIEELEE 241
           RQQ++ EF  L + L+E+Q +LL++LE ++ DIL++  E    +  +    + L  E+E 
Sbjct: 190 RQQILREFEELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDLAHLAAEVEG 249

Query: 242 KNERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPLQREMKMFLEKL 301
           K  +   E+L D++STL +CE  K  +  +VS EL +   +FP+Q   L++ +K  +   
Sbjct: 250 KCLQSGFEMLKDVKSTLEKCEKVKTMEVTSVSIELEKNFSNFPRQYFALRKILKQLI--- 306

Query: 302 CFELDYEPAHISLDPQTSHPKLLLSEDHQRAQF-SYKWQNSPDNPQRFDRATCVLAHTGI 360
                   A ++LDP+T+HP L+LSED +  +F   + ++ PD P+RF    CVLA  G 
Sbjct: 307 --------ADVTLDPETAHPNLVLSEDRKSVKFVETRLRDLPDTPRRFTFYPCVLATEGF 358

Query: 361 TGGRHTWVVSI-DLAHGGSCTVGVVSEDVQRKGELRLRPEEGVWAVRLAWGFVSALGSFP 419
           T GRH W V + D  H     VGV  + V RKGEL   PE G W VRL  G   A  + P
Sbjct: 359 TSGRHYWEVEVGDKTH---WAVGVCRDSVSRKGELTPLPETGYWRVRLWNGDKYAATTTP 415

Query: 420 -TRLTLKEQPRQVRVSLDYEVGWVTFTNAVTREPIYTFTASFTRKVIPFF 468
            T L +K +P++V + LDYE G ++F N   R  IYTFT +FT K+ P F
Sbjct: 416 FTPLHIKVKPKRVGIFLDYEAGTLSFYNVTDRSHIYTFTDTFTEKLWPLF 465


>gi|4508005 tripartite motif-containing 26 [Homo sapiens]
          Length = 539

 Score =  303 bits (777), Expect = 2e-82
 Identities = 187/541 (34%), Positives = 284/541 (52%), Gaps = 66/541 (12%)

Query: 1   MASAASVTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLC 60
           MA++A + SL +EV C IC   LR+PVTIDCGH FCR+C T    I G      P CPLC
Sbjct: 1   MATSAPLRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTTDVRPISG----SRPVCPLC 56

Query: 61  KEPFRPGSFRPNWQLANVVENIERLQLVSTLGLGE-------EDVCQEHGEKIYFFCEDD 113
           K+PF+  + RP WQLA++VENIERL++      GE         +C+ H EK++++CEDD
Sbjct: 57  KKPFKKENIRPVWQLASLVENIERLKVDKGRQPGEVTREQQDAKLCERHREKLHYYCEDD 116

Query: 114 EMQLCVVCREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQV 173
              LCV+CRE+ EH  HT   +E AA P+RE+I   L  LR++R++IQ  Q++    +  
Sbjct: 117 GKLLCVMCRESREHRPHTAVLMEKAAQPHREKILNHLSTLRRDRDKIQGFQAKGEADILA 176

Query: 174 LLTQVSTKRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFS 233
            L ++  +RQ +++EF    +FL E++  LL QL   + ++   R++F     GE+ R +
Sbjct: 177 ALKKLQDQRQYIVAEFEQGHQFLREREEHLLEQLAKLEQELTEGREKFKSRGVGELARLA 236

Query: 234 ALIEELEEKNERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPLQRE 293
            +I ELE K ++PA EL+ D R  L R   +K      ++  + ++  +F  + L LQR 
Sbjct: 237 LVISELEGKAQQPAAELMQDTRDFLNRYPRKKFWVGKPIARVVKKKTGEFSDKLLSLQRG 296

Query: 294 MKMFLEKLCFELDYEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDRATC 353
           ++ F  KL  +L+Y+   ++LDPQ++   L LSED +   ++  ++++  +PQ+FD    
Sbjct: 297 LREFQGKLLRDLEYKTVSVTLDPQSASGYLQLSEDWKCVTYTSLYKSAYLHPQQFDCEPG 356

Query: 354 VLAHTGITGGRHTWVVSI-------------------------DLAHGGSCTVGVVSEDV 388
           VL   G T G+  W V +                         +  +G         ED 
Sbjct: 357 VLGSKGFTWGKVYWEVEVEREGWSEDEEEGDEEEEGEEEEEEEEAGYGDGYDDWETDEDE 416

Query: 389 QRKGELRLRPEE------------------------------GVWAVRLAWGFVSALGSF 418
           +  G+     EE                              GVWA+RL+   + A  S 
Sbjct: 417 ESLGDEEEEEEEEEEEVLESCMVGVARDSVKRKGDLSLRPEDGVWALRLSSSGIWANTSP 476

Query: 419 PTRLTLKEQPRQVRVSLDYEVGWVTFTNAVTREPIYTFTASFTRKVIPFFGLWGRGSSFS 478
              L    +PR+V ++LDYE G VTFTNA ++E IYTFTA+FTR+++PF  L   G+   
Sbjct: 477 EAELFPALRPRRVGIALDYEGGTVTFTNAESQELIYTFTATFTRRLVPFLWLKWPGTRLL 536

Query: 479 L 479
           L
Sbjct: 537 L 537


>gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]
          Length = 518

 Score =  300 bits (769), Expect = 1e-81
 Identities = 181/500 (36%), Positives = 276/500 (55%), Gaps = 52/500 (10%)

Query: 2   ASAASVTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLCK 61
           ++AA++ +L  E +C +C   L+EPV I+CGHNFC+AC+TR+ E    DLE    CP+C+
Sbjct: 15  STAAALENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWE----DLERDFPCPVCR 70

Query: 62  EPFRPGSFRPNWQLANVVENIERLQLVSTLGLGEEDVCQEHGEKIYFFCEDDEMQLCVVC 121
           +  R  S RPN QL ++VE  ++LQ V    + +E +C +H E +  FC +D+  +C++C
Sbjct: 71  KTSRYRSLRPNRQLGSMVEIAKQLQAVKRK-IRDESLCPQHHEALSLFCYEDQEAVCLIC 129

Query: 122 REAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQVLLTQVSTK 181
             +  H  HT+  L+DA   Y+E++ KCL+ L ++ +EI   +S E K+   L   V ++
Sbjct: 130 AISHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVESR 189

Query: 182 RQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFSALIEELEE 241
           RQQ++ EF  L + L+E+Q +LL++LE ++ DIL++  E    +  +    + L  E+E 
Sbjct: 190 RQQILREFEELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDLAHLAAEVEG 249

Query: 242 KNERPARELLTDIRSTLI------------------------------RCETRKCRKPVA 271
           K  +   E+L D++STL                               RCE  K  +  +
Sbjct: 250 KCLQSGFEMLKDVKSTLEKNIPRKFGGSLSTICPRDHKALLGLVKEINRCEKVKTMEVTS 309

Query: 272 VSPELGQRIRDFPQQALPLQREMKMFLEKLCFELDYEPAHISLDPQTSHPKLLLSEDHQR 331
           VS EL +   +FP+Q   L++ +K  +           A ++LDP+T+HP L+LSED + 
Sbjct: 310 VSIELEKNFSNFPRQYFALRKILKQLI-----------ADVTLDPETAHPNLVLSEDRKS 358

Query: 332 AQF-SYKWQNSPDNPQRFDRATCVLAHTGITGGRHTWVVSI-DLAHGGSCTVGVVSEDVQ 389
            +F   + ++ PD P+RF    CVLA  G T GRH W V + D  H     VGV  + V 
Sbjct: 359 VKFVETRLRDLPDTPRRFTFYPCVLATEGFTSGRHYWEVEVGDKTHWA---VGVCRDSVS 415

Query: 390 RKGELRLRPEEGVWAVRLAWGFVSALGSFP-TRLTLKEQPRQVRVSLDYEVGWVTFTNAV 448
           RKGEL   PE G W VRL  G   A  + P T L +K +P++V + LDYE G ++F N  
Sbjct: 416 RKGELTPLPETGYWRVRLWNGDKYAATTTPFTPLHIKVKPKRVGIFLDYEAGTLSFYNVT 475

Query: 449 TREPIYTFTASFTRKVIPFF 468
            R  IYTFT +FT K+ P F
Sbjct: 476 DRSHIYTFTDTFTEKLWPLF 495


>gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens]
          Length = 511

 Score =  280 bits (715), Expect = 3e-75
 Identities = 174/492 (35%), Positives = 258/492 (52%), Gaps = 25/492 (5%)

Query: 5   ASVTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPT-------- 56
           A    L  E  C IC    REPV+++CGH+FCRAC+ R  E PG     + T        
Sbjct: 18  ALAAELQGEATCSICLELFREPVSVECGHSFCRACIGRCWERPGAGSVGAATRAPPFPLP 77

Query: 57  CPLCKEPFRPGSFRPNWQLANVVENIERLQLVSTLGLGEEDV-----------CQEHGEK 105
           CP C+EP RP   RPN QLA V   + R  L +    GE              C +HGE 
Sbjct: 78  CPQCREPARPSQLRPNRQLAAVATLLRRFSLPAAAP-GEHGSQAAAARAAAARCGQHGEP 136

Query: 106 IYFFCEDDEMQLCVVCREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQS 165
              +C+DD   +CVVC  A EH  H +  L++A    +E +   L+ L+KE E+ +  +S
Sbjct: 137 FKLYCQDDGRAICVVCDRAREHREHAVLPLDEAVQEAKELLESRLRVLKKELEDCEVFRS 196

Query: 166 RENKRMQVLLTQVSTKRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLV 225
            E K  + LL Q++ ++++V +EF  LR FL EQ+  LL +LE    ++ ++++E    +
Sbjct: 197 TEKKESKELLKQMAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQL 256

Query: 226 AGEICRFSALIEELEEKNERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQ 285
             EI + S L  +++E  ++P  + L + +STL RC      KP  VS E+  ++ +   
Sbjct: 257 GVEITQLSKLSSQIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNVSL 316

Query: 286 QALPLQREMKMFLEKLCFELD-YEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDN 344
           +   L+  +K F E L  EL+  E   ++LDP T++P+L+LS D +  +   + Q+ P++
Sbjct: 317 KTFVLKGMLKKFKEDLRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQDLPNH 376

Query: 345 PQRFDRATCVLAHTGITGGRHTWVVSIDLAHGGSCTVGVVSEDVQRKGELRLRPEEGVWA 404
           P RFD  T VLA  G + GRH W V +    G +   GV  E V+RKG     PEEGVWA
Sbjct: 377 PCRFDTNTRVLASCGFSSGRHHWEVEVGSKDGWA--FGVARESVRRKGLTPFTPEEGVWA 434

Query: 405 VRLAWGFVSALGSFPTRLTLK-EQPRQVRVSLDYEVGWVTFTNAVTREPIYTFTASFTRK 463
           ++L  G   A+ S P R  L      +VRV+LD EVG V+F        +YTF  +F  +
Sbjct: 435 LQLNGGQYWAVTS-PERSPLSCGHLSRVRVALDLEVGAVSFYAVEDMRHLYTFRVNFQER 493

Query: 464 VIPFFGLWGRGS 475
           V P F +   G+
Sbjct: 494 VFPLFSVCSTGT 505


>gi|37622899 ring finger protein 137 [Homo sapiens]
          Length = 485

 Score =  278 bits (711), Expect = 8e-75
 Identities = 166/485 (34%), Positives = 269/485 (55%), Gaps = 40/485 (8%)

Query: 1   MASAASVTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLC 60
           M   A V ++ +EV CPIC   LREP++IDCGH+FC +CL+   EIPG       TCPLC
Sbjct: 1   MDPTALVEAIVEEVACPICMTFLREPMSIDCGHSFCHSCLSGLWEIPGESQNWGYTCPLC 60

Query: 61  KEPFRPGSFRPNWQLANVVENIERLQLVSTLGLGEEDVCQEHGEKIYFFCEDDEMQLCVV 120
           + P +P + RPNWQLANVVE +  L+L   +GL + D+C+ HGEK+  FC++D + +C  
Sbjct: 61  RAPVQPRNLRPNWQLANVVEKVRLLRLHPGMGL-KGDLCERHGEKLKMFCKEDVLIMCEA 119

Query: 121 CREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQVLLTQVST 180
           C ++ EH  H++  +ED A  Y+ ++H+ L+ L+KE+EE  +++  E KR      QV T
Sbjct: 120 CSQSPEHEAHSVVPMEDVAWEYKWELHEALEHLKKEQEEAWKLEVGERKRTATWKIQVET 179

Query: 181 KRQQVISEFAHLRKFLEEQQ----------SILLAQLESQDGDILR--QRDEFDLLVAGE 228
           ++Q ++ EF   ++ LE++Q          +  LA L+ +  + ++  + +  +L+   +
Sbjct: 180 RKQSIVWEFEKYQRLLEKKQPPHRQLGAEVAAALASLQREAAETMQKLELNHSELIQQSQ 239

Query: 229 ICRFSALIEELEEKNERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQAL 288
           +     +I EL+E+++RP R +L DI+  L R ++   ++P  +S EL    R      L
Sbjct: 240 V--LWRMIAELKERSQRPVRWMLQDIQEVLNRSKSWSLQQPEPISLELKTDCR-----VL 292

Query: 289 PLQREMKMFLEKLCFELDYEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRF 348
            L+  +K +            A + LDP T++ +L++SED +R  +    Q  PDNP+RF
Sbjct: 293 GLREILKTY-----------AADVRLDPDTAYSRLIVSEDRKRVHYGDTNQKLPDNPERF 341

Query: 349 DRATCVLAHTGITGGRHTWVVSI-DLAHGGSCTVGVVSEDVQRKGELRLRPEEGVWAVRL 407
            R   VL    I+ GRH W V + D +  G   +GV  ++V RK  + L P  G W +RL
Sbjct: 342 YRYNIVLGSQCISSGRHYWEVEVGDRSEWG---LGVCKQNVDRKEVVYLSPHYGFWVIRL 398

Query: 408 AWG--FVSALGSFPTRLTLKEQPRQVRVSLDYEVGWVTFTNAV-TREPIYTFTA-SFTRK 463
             G  + +    +P  L+L   PR+V + +DYE   ++F N       I+TF    F  +
Sbjct: 399 RKGNEYRAGTDEYPI-LSLPVPPRRVGIFVDYEAHDISFYNVTDCGSHIFTFPRYPFPGR 457

Query: 464 VIPFF 468
           ++P+F
Sbjct: 458 LLPYF 462


>gi|5730009 ret finger protein [Homo sapiens]
          Length = 513

 Score =  276 bits (705), Expect = 4e-74
 Identities = 167/482 (34%), Positives = 259/482 (53%), Gaps = 18/482 (3%)

Query: 1   MASAASVTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLC 60
           MAS +    L  E  CP+C     EP+ +DCGHN C ACL R         E + +CP C
Sbjct: 1   MASGSVAECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTA----ETNVSCPQC 56

Query: 61  KEPFRPGSFRPNWQLANVVENIERLQLVSTLGLGEE-DVCQEHGEKIYFFCEDDEMQLCV 119
           +E F     RPN  LANV + +++L+     G G E  VC++H E +  +CE+D+M +CV
Sbjct: 57  RETFPQRHMRPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICV 116

Query: 120 VCREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQVLLTQVS 179
           VC  + EH  H++  LE+A   ++EQI   L  L++ ++  +  +++  +    LL+   
Sbjct: 117 VCDRSREHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQ 176

Query: 180 TKRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFSALIEEL 239
            +R++++ EF  L   L+E +  LLA+LE  D  I    +      +  I   S+LI +L
Sbjct: 177 MEREKIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQL 236

Query: 240 EEKNERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPLQREMKMFLE 299
           EEK ++P RELL DI  TL R E  +  +P    P+L ++I  F Q+ L L   +K F E
Sbjct: 237 EEKQQQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTE 296

Query: 300 KLCFELD---------YEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDR 350
           K+  +++              ++LDP T++P L+LS++ ++ ++SY  Q+ PDNP+RF+ 
Sbjct: 297 KMQSDMEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERFNL 356

Query: 351 ATCVLAHTGITGGRHTWVVSIDLAHGGSCTVGVVSEDVQRKGELRLRPEEGVWAVRLAWG 410
             CVL       GRH W   +++      T+GV  + V RKG +   P+ G WAV L +G
Sbjct: 357 FPCVLGSPCFIAGRHYW--EVEVGDKAKWTIGVCEDSVCRKGGVTSAPQNGFWAVSLWYG 414

Query: 411 -FVSALGSFPTRLTLKEQPRQVRVSLDYEVGWVTFTNAVTREPIYTFT-ASFTRKVIPFF 468
               AL S  T L L+   ++V + LDY+ G V+F N   R   +TF+ A+F   V P+F
Sbjct: 415 KEYWALTSPMTALPLRTPLQRVGIFLDYDAGEVSFYNVTERCHTFTFSHATFCGPVRPYF 474

Query: 469 GL 470
            L
Sbjct: 475 SL 476


>gi|112421127 tripartite motif-containing 58 [Homo sapiens]
          Length = 486

 Score =  261 bits (666), Expect = 1e-69
 Identities = 163/471 (34%), Positives = 241/471 (51%), Gaps = 26/471 (5%)

Query: 1   MASAASVTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLC 60
           MA A     L ++  CP+C   L+EPV++DCGH+FC  C++ +CE           CP C
Sbjct: 1   MAWAPPGERLREDARCPVCLDFLQEPVSVDCGHSFCLRCISEFCEKSDGAQGGVYACPQC 60

Query: 61  KEPFRPGSFRPNWQLANVVENIERLQLVSTLGLGEEDVCQEHGEKIYFFCEDDEMQLCVV 120
           + PFRP  FRPN QLA +VE++ RL L +  G      C  HGE +  FCE+DE  LC V
Sbjct: 61  RGPFRPSGFRPNRQLAGLVESVRRLGLGAGPGARR---CARHGEDLSRFCEEDEAALCWV 117

Query: 121 CREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQVLLTQVST 180
           C    EH TH    L++AA  Y+ ++   L+ +RKE E+    ++   K+  +   +V  
Sbjct: 118 CDAGPEHRTHRTAPLQEAAGSYQVKLQMALELMRKELEDALTQEANVGKKTVIWKEKVEM 177

Query: 181 KRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFSALIEELE 240
           +RQ+   EF   R FL +++   L +LE+++   L++  E    +  +      L +EL+
Sbjct: 178 QRQRFRLEFEKHRGFLAQEEQRQLRRLEAEERATLQRLRESKSRLVQQSKALKELADELQ 237

Query: 241 EKNERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPLQREMKMFLEK 300
           E+ +RPA  LL  +R  L R +     +   +  EL           +P +RE+   L K
Sbjct: 238 ERCQRPALGLLEGVRGVLSRSKAVTRLEAENIPMELKTAC------CIPGRREL---LRK 288

Query: 301 LCFELDYEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDRATCVLAHTGI 360
             F++D     + LDP T+HP LLL+ D +  Q    W++ P+NP+RFD   C+L     
Sbjct: 289 --FQVD-----VKLDPATAHPSLLLTADLRSVQDGEPWRDVPNNPERFDTWPCILGLQSF 341

Query: 361 TGGRHTWVVSIDLAHGGSCTVGVVSEDVQRKGELRLRPEEGVWAVRLAWG---FVSALGS 417
           + GRH W V +    G    +GV  + + RKGE    PE GVWA+ L  G    V A  S
Sbjct: 342 SSGRHYWEVLV--GEGAEWGLGVCQDTLPRKGETTPSPENGVWALWLLKGNEYMVLASPS 399

Query: 418 FPTRLTLKEQPRQVRVSLDYEVGWVTFTNAVTREPIYTFTASFTRKVIPFF 468
            P  L   E PR + + LDYE G ++F N      IYTF   F+  + P+F
Sbjct: 400 VP--LLQLESPRCIGIFLDYEAGEISFYNVTDGSYIYTFNQLFSGLLRPYF 448


>gi|157743261 tripartite motif-containing 75 [Homo sapiens]
          Length = 468

 Score =  242 bits (617), Expect = 6e-64
 Identities = 147/470 (31%), Positives = 243/470 (51%), Gaps = 22/470 (4%)

Query: 1   MASAASVTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLC 60
           MA AA++T L  E  C IC   L +PVTI+CGHNFCR+C+ +       DL+E   CP+C
Sbjct: 1   MAVAAALTGLQAEAKCSICLDYLSDPVTIECGHNFCRSCIQQ----SWLDLQELFPCPVC 56

Query: 61  KEPFRPGSFRPNWQLANVVENIERLQLVSTLGLGEED--VCQEHGEKIYFFCEDDEMQLC 118
           +   + G FR N QL  ++E  + LQ   +    +E+  +C++H + +  FC++D M LC
Sbjct: 57  RHQCQEGHFRSNTQLGRMIEIAKLLQSTKSNKRKQEETTLCEKHNQPLSVFCKEDLMVLC 116

Query: 119 VVCREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQVLLTQV 178
            +C +  +H  H +R +E AA  YR++    ++ L+K+  ++Q++ S ++K+   L   V
Sbjct: 117 PLCTQPPDHQGHHVRPIEKAAIHYRKRFCSYIQPLKKQLADLQKLISTQSKKPLELREMV 176

Query: 179 STKRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFSALIEE 238
             +RQ++ SEF HL +FL+ +Q  +L++L  ++ D  ++        +       + + +
Sbjct: 177 ENQRQELSSEFEHLNQFLDREQQAVLSRLAEEEKDNQQKLSANITAFSNYSATLKSQLSK 236

Query: 239 LEEKNERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPLQREMKMFL 298
           + E +E    ELL+ I+   I  E+     P   S  L +    FP Q   LQR +K F 
Sbjct: 237 VVELSELSELELLSQIK---IFYESENESSPSIFSIHLKRDGCSFPPQYSALQRIIKKF- 292

Query: 299 EKLCFELDYEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDRATCVLAHT 358
                        I LDP+T+HP L++SED +R +F+ + Q  P  P+RF     VL   
Sbjct: 293 ----------KVEIILDPETAHPNLIVSEDKKRVRFTKRKQKVPGFPKRFTVKPVVLGFP 342

Query: 359 GITGGRHTWVVSIDLAHGGSCTVGVVSEDVQRKGELRLRPEEGVWAVRLAWGFVSALGSF 418
               GRH W   I++       +G+  + +  K       ++  W + L      A G+F
Sbjct: 343 YFHSGRHFW--EIEVGDKSEWAIGICKDSLPTKARRPSSAQQECWRIELQDDGYHAPGAF 400

Query: 419 PTRLTLKEQPRQVRVSLDYEVGWVTFTNAVTREPIYTFTASFTRKVIPFF 468
           PT L L+ + R + + LDYE+G ++F N   +  I TFT +FT  + P+F
Sbjct: 401 PTPLLLEVKARAIGIFLDYEMGEISFYNMAEKSHICTFTDTFTGPLRPYF 450


>gi|5454014 tripartite motif-containing 38 [Homo sapiens]
          Length = 465

 Score =  240 bits (612), Expect = 2e-63
 Identities = 154/480 (32%), Positives = 243/480 (50%), Gaps = 36/480 (7%)

Query: 1   MASAASVTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDL--EESPTCP 58
           MAS  S   + +E  C IC   +  PV+I+CGH++C  C+T + + P      +E+  CP
Sbjct: 1   MASTTSTKKMMEEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQETFCCP 60

Query: 59  LCKEPFRPGSFRPNWQLANVVENIERLQLVSTLGLGEEDVCQEHGEKIYFFCEDDEMQLC 118
            C+ PF   S RPN QL +++E ++           +E  C+EHGE+ + FCED+   +C
Sbjct: 61  QCRAPFHMDSLRPNKQLGSLIEALKETD--------QEMSCEEHGEQFHLFCEDEGQLIC 112

Query: 119 VVCREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQVLLTQV 178
             C  A +H  HT   +ED    Y+E++ K +  L++  +   E +     R+     +V
Sbjct: 113 WRCERAPQHKGHTTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRITKWKEKV 172

Query: 179 STKRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFSALIEE 238
             +RQ++ S+F +L+ FL E++   L +LE ++   L +  +++  +  +     + I E
Sbjct: 173 QIQRQKIRSDFKNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHILE 232

Query: 239 LEEKNERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPLQREMKMFL 298
           LEEK +  A++LL ++  TL R    K     AVS EL                     +
Sbjct: 233 LEEKCQGSAQKLLQNVNDTLSRSWAVKLETSEAVSLELHTMCN----------------V 276

Query: 299 EKLCFE----LDYEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDRATCV 354
            KL F+    L      ++LDP T+H +L+LSED ++    Y  +N   + +RF    CV
Sbjct: 277 SKLYFDVKKMLRSHQVSVTLDPDTAHHELILSEDRRQVTRGYTQENQDTSSRRFTAFPCV 336

Query: 355 LAHTGITGGRHTWVVSIDLAHGGSCTVGVVSEDVQRKGELRLRPEEGVWAVRLA--WGFV 412
           L   G T GR  +   +D+  G    +GV  E+VQR   ++  P+ G W +RL    G+V
Sbjct: 337 LGCEGFTSGRRYF--EVDVGEGTGWDLGVCMENVQRGTGMKQEPQSGFWTLRLCKKKGYV 394

Query: 413 SALGSFPTRLTLKEQPRQVRVSLDYEVGWVTFTNAVTREPIYTF-TASFTRKVIPFFGLW 471
            AL S PT L L EQP  V + LDYE G V+F N  T   I+TF  ASF+  + P+F ++
Sbjct: 395 -ALTSPPTSLHLHEQPLLVGIFLDYEAGVVSFYNGNTGCHIFTFPKASFSDTLRPYFQVY 453


>gi|15208660 tripartite motif protein 21 [Homo sapiens]
          Length = 475

 Score =  228 bits (582), Expect = 7e-60
 Identities = 153/471 (32%), Positives = 242/471 (51%), Gaps = 28/471 (5%)

Query: 1   MASAASVTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLC 60
           MASAA +T + +EV CPIC     EPV+I+CGH+FC+ C+++  +  G        CP+C
Sbjct: 1   MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGS------VCPVC 54

Query: 61  KEPFRPGSFRPNWQLANVVENIERLQLVSTLGLGEEDVCQEHGEKIYFFCEDDEMQLCVV 120
           ++ F   + RPN QLAN+V N++ +   +  G   E  C  HGE+++ FCE D   LC V
Sbjct: 55  RQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGER-CAVHGERLHLFCEKDGKALCWV 113

Query: 121 CREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQVLLTQVST 180
           C ++ +H  H M  LE+AA  Y+E++   L  LR+++E  ++++     +       V T
Sbjct: 114 CAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVET 173

Query: 181 KRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFSALIEELE 240
           ++ ++ +EF   + FL E++   L +LE  + + LR   E +  +A +      LI EL+
Sbjct: 174 QKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELD 233

Query: 241 EKNERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPLQREMKMFLEK 300
            +    A ELL ++   L R E+   +     SPEL           +P  ++M     +
Sbjct: 234 RRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCH------VPGLKKML----R 283

Query: 301 LCFELDYEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDRATCVLAHTGI 360
            C        HI+LDP T++P L+LSED ++ +     Q+ P N +RFD    VL     
Sbjct: 284 TC------AVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHF 337

Query: 361 TGGRHTWVVSIDLAHGGSCTVGVVSEDVQRKGELRLRPEEGVWAVRLAWGFVSALGSFP- 419
             G+H W   +D+    +  +GV  + V+RKG   L  + G W + L        G++P 
Sbjct: 338 HSGKHYW--EVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQ 395

Query: 420 TRLTLKEQPRQVRVSLDYEVGWVTFTNAVTR-EPIYTFT-ASFTRKVIPFF 468
           T L L+  P QV + LDYE G V+F N       IY+F+  +FT  + PFF
Sbjct: 396 TPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFF 446


>gi|21630277 tripartite motif-containing 11 [Homo sapiens]
          Length = 468

 Score =  225 bits (574), Expect = 6e-59
 Identities = 154/470 (32%), Positives = 231/470 (49%), Gaps = 35/470 (7%)

Query: 1   MASAASVTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESP-TCPL 59
           MA+    T+L +E  C IC     +PV  DCGHNFCR C+ R    P     E P  CP 
Sbjct: 1   MAAPDLSTNLQEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQP-----EGPYACPE 55

Query: 60  CKEPFRPGSFRPNWQLANVVENIERLQLVSTLGLGEEDVCQEHGEKIYFFCEDDEMQLCV 119
           C+E     + RPN  LA + E   RL   S +  G   VC  H E +  FC D+   LC 
Sbjct: 56  CRELSPQRNLRPNRPLAKMAEMARRLHPPSPVPQG---VCPAHREPLAAFCGDELRLLCA 112

Query: 120 VCREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQVLLTQVS 179
            C  +GEH  H +R L+DAA   + ++ K L+ LRK+ ++    Q++ ++   +    V 
Sbjct: 113 ACERSGEHWAHRVRPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMVE 172

Query: 180 TKRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFSALIEEL 239
           ++RQ V+ EF  LR+ L E++  LL +LE ++ ++L +  E    +  +    + LI EL
Sbjct: 173 SQRQNVLGEFERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAEL 232

Query: 240 EEKNERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPLQREMKMFLE 299
           E + + PA  LL DI+  L R +  K + P  V  EL + +   P     L+R       
Sbjct: 233 EGRCQLPALGLLQDIKDALRRVQDVKLQPPEVVPMEL-RTVCRVPGLVETLRR------- 284

Query: 300 KLCFELDYEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDRATCVLAHTG 359
              F  D     ++LDP T++P+L+LSED +  Q     Q  PD+P+RFD   CVL    
Sbjct: 285 ---FRGD-----VTLDPDTANPELILSEDRRSVQRGDLRQALPDSPERFDPGPCVLGQER 336

Query: 360 ITGGRHTWVVSIDLAHGGSCTVGVVSEDVQRKGELRLRPEEGVWAVRLAWGFVSALGSFP 419
            T GRH W   +++    S  +GV  E+V RK +  L    G W +     + ++  S  
Sbjct: 337 FTSGRHYW--EVEVGDRTSWALGVCRENVNRKEKGELSAGNGFWILVFLGSYYNS--SER 392

Query: 420 TRLTLKEQPRQVRVSLDYEVGWVTFTNAVTREPIYTFTASFTRKVIPFFG 469
               L++ PR+V + LDYE G ++F +A     ++ F        IPF G
Sbjct: 393 ALAPLRDPPRRVGIFLDYEAGHLSFYSATDGSLLFIFPE------IPFSG 436


>gi|22749269 ring finger protein 129 [Homo sapiens]
          Length = 471

 Score =  213 bits (541), Expect = 4e-55
 Identities = 141/472 (29%), Positives = 247/472 (52%), Gaps = 24/472 (5%)

Query: 1   MASAASVTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLC 60
           M    ++ +L +E +CPIC   L++PVTI+CGHNFCR+CL+    +   DL+++  CP+C
Sbjct: 1   MEFVTALVNLQEESSCPICLEYLKDPVTINCGHNFCRSCLS----VSWKDLDDTFPCPVC 56

Query: 61  KEPFRPGSFRPNWQLANVVENIERLQLVSTLGLGEED--VCQEHGEKIYFFCEDDEMQLC 118
           +  F   SFR N QL N+ E  ++LQ+  +    +++  +C++H + +  FC  D   LC
Sbjct: 57  RFCFPYKSFRRNPQLRNLTEIAKQLQIRRSKRKRQKENAMCEKHNQFLTLFCVKDLEILC 116

Query: 119 VVCREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQVLLTQV 178
             C  + +H  H +  ++ AA+ +RE +   L+ LR   E ++++   +  +   L  +V
Sbjct: 117 TQCSFSTKHQKHYICPIKKAASYHREILEGSLEPLRNNIERVEKVIILQGSKSVELKKKV 176

Query: 179 STKRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFSALIEE 238
             KR+++ SEF  +R FL+ +Q ++L Q++ ++ +IL + +E  + ++  +     L+ E
Sbjct: 177 EYKREEINSEFEQIRLFLQNEQEMILRQIQDEEMNILAKLNENLVELSDYVSTLKHLLRE 236

Query: 239 LEEKNERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPLQREMKMFL 298
           +E K+ +   ELLT  +S   + +  KC  P   S  L +     P Q   L R +K F 
Sbjct: 237 VEGKSVQSNLELLTQAKSMHHKYQNLKC--PELFSFRLTKYGFSLPPQYSGLDRIIKPF- 293

Query: 299 EKLCFELDYEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDRATCVLAHT 358
                        + LD  T+HP+LL+SED +  ++  K +N   +P+RF     VL   
Sbjct: 294 ----------QVDVILDLNTAHPQLLVSEDRKAVRYERKKRNICYDPRRFYVCPAVLGSQ 343

Query: 359 GITGGRHTWVVSIDLAHGGSCTVGVVSEDVQRKGELRLRPEEGVWAV--RLAWGFVSALG 416
             + GRH W   +++ +     +GV  + + R  + +     G WA+   +  G+V A G
Sbjct: 344 RFSSGRHYW--EVEVGNKPKWILGVCQDCLLRNWQDQPSVLGGFWAIGRYMKSGYV-ASG 400

Query: 417 SFPTRLTLKEQPRQVRVSLDYEVGWVTFTNAVTREPIYTFTASFTRKVIPFF 468
              T+L    +P ++ + LDYE+G ++F N   R  +YTF   FT  V P+F
Sbjct: 401 PKTTQLLPVVKPSKIGIFLDYELGDLSFYNMNDRSILYTFNDCFTEAVWPYF 452


>gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo
           sapiens]
          Length = 474

 Score =  211 bits (536), Expect = 2e-54
 Identities = 143/481 (29%), Positives = 229/481 (47%), Gaps = 47/481 (9%)

Query: 10  LADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLCKEPFRPGSF 69
           + +E+ CPIC    ++PV+I+CGHNFCR CL R     G        CP C+ P  P + 
Sbjct: 6   IQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFP----CPECRHPSAPAAL 61

Query: 70  RPNWQLANVVENIERLQLVSTLGLGEEDVCQEHGEKIYFFCEDDEMQLCVVCREAGEHAT 129
           RPNW LA + E  +R +L    G     +C  H E +  FCEDD+  +C+VCRE+ EH T
Sbjct: 62  RPNWALARLTEKTQRRRL----GPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQT 117

Query: 130 HTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQVLLTQVSTKRQQVISEF 189
           H M  +++A   YRE++ K  + L  + +++  +Q  E K       ++ ++R ++ +EF
Sbjct: 118 HAMAPIDEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRISTEF 177

Query: 190 AHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFSALIEELEEKNERPARE 249
           + L  FL E++ + L +L  ++ +  ++ +E  L +   I     LI E+ EK++ P  E
Sbjct: 178 SKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAPTLE 237

Query: 250 LLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPLQREMKMFLEKLCFELDYEP 309
           LL + +  L R E +     +       + ++      +PL +EM          L    
Sbjct: 238 LLQNPKEVLTRSEIQDVNYSL-------EAVKVKTVCQIPLMKEM----------LKRFQ 280

Query: 310 AHISLDPQTSHPKLLLSEDHQRAQ----------FSYKWQNSPD--NPQ------RFDRA 351
             ++L   T+HPKL+ S++ +  +          FS  W       NPQ      RF   
Sbjct: 281 VAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHL 340

Query: 352 TCVLAHTGITGGRHTWVVSIDLAHGGSCTVGVVSEDVQR-KGELRLRPEEGVWAVRLAWG 410
            CVL     T G+H W   ++        VGV  EDV       ++ P+ G+WA+  +  
Sbjct: 341 PCVLGKNVFTSGKHYW--EVESRDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIYWSAA 398

Query: 411 FVSALGSFPTRLTLKEQP-RQVRVSLDYEVGWVTFTNAVTREPIYTFTASFTRKVIPFFG 469
               L  FP   T +E    +V V LD   G V+F +AV    ++TF+ S   ++ PFF 
Sbjct: 399 GYWPLIGFPGTPTQQEPALHRVGVYLDRGTGNVSFYSAVDGVHLHTFSCSSVSRLRPFFW 458

Query: 470 L 470
           L
Sbjct: 459 L 459


>gi|42516572 tripartite motif-containing 41 isoform 1 [Homo sapiens]
          Length = 630

 Score =  205 bits (522), Expect = 6e-53
 Identities = 144/464 (31%), Positives = 228/464 (49%), Gaps = 39/464 (8%)

Query: 47  PGPDLEESPTCPLCKEPFRPGSFRPNWQLANVVENIERLQLVSTLG--LGEEDVCQEHGE 104
           P P      TCP C++ F   SFRPN QLAN+V+ I ++      G  + ++ +C +H E
Sbjct: 173 PPPAPRRCFTCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQE 232

Query: 105 KIYFFCEDDEMQLCVVCREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQ 164
            +  FCE DE  +CVVCRE+  H  H++  LE+    Y+ ++   ++ LRK  E +Q+++
Sbjct: 233 ALKLFCEVDEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMK 292

Query: 165 SRENKRMQVLLTQVSTKRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLL 224
           ++E +R+  L +Q+ ++   V SEF  L +FL E+Q+ L  +L       L +       
Sbjct: 293 AKEERRVTELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASR 352

Query: 225 VAGEICRFSALIEELEEKNERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQ-RIRDF 283
           +A +  + S L+ E +E++++    LL DI+ T  RCE  + + P   SP+  Q    DF
Sbjct: 353 LAEQAAQLSRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDPCQPHSHDF 412

Query: 284 PQQALPLQREMKMFLEKLCFELDYEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPD 343
              A+ +++  +MF +    +L       +LDP T+HP L+LS D +  + + + Q   D
Sbjct: 413 LTDAI-VRKMSRMFCQAARVDL-------TLDPDTAHPALMLSPDRRGVRLAERRQEVAD 464

Query: 344 NPQRFDRATCVLAHTGITGGRHTWVVSIDLAHG------------------GSCTVGVVS 385
           +P+RF    CVL   G   GRH W V +    G                  G  +VG   
Sbjct: 465 HPKRFSADCCVLGAQGFRSGRHYWEVEVGGRRGWAVGAARESTHHKEKVGPGGSSVGSGD 524

Query: 386 EDVQRKGELRLR---PEEG-----VWAVRLAWGFVSALGSFP-TRLTLKEQPRQVRVSLD 436
               R    R R   P++      VW V        A  S   T L+  E+PR+  V LD
Sbjct: 525 ASSSRHHHRRRRLHLPQQPLLQREVWCVGTNGKRYQAQSSTEQTLLSPSEKPRRFGVYLD 584

Query: 437 YEVGWVTFTNAVTREPIYTFTASFT-RKVIPFFGLWGRGSSFSL 479
           YE G + F NA T   ++TF+A+F   +V PFF +  +G+   L
Sbjct: 585 YEAGRLGFYNAETLAHVHTFSAAFLGERVFPFFRVLSKGTRIKL 628



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 18/36 (50%), Positives = 24/36 (66%)

Query: 7  VTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTR 42
          V +L +E  C IC     +PV+I CGHNFCR C+T+
Sbjct: 11 VQTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQ 46


>gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo
           sapiens]
          Length = 500

 Score =  197 bits (500), Expect = 2e-50
 Identities = 145/507 (28%), Positives = 229/507 (45%), Gaps = 73/507 (14%)

Query: 10  LADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLCKEPFRPGSF 69
           + +E+ CPIC    ++PV+I+CGHNFCR CL R     G        CP C+ P  P + 
Sbjct: 6   IQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFP----CPECRHPSAPAAL 61

Query: 70  RPNWQLANVVENIERLQLVSTLGLGEEDVCQEHGEKIYFFCEDDEMQLCVVCREAGEHAT 129
           RPNW LA + E  +R +L    G     +C  H E +  FCEDD+  +C+VCRE+ EH T
Sbjct: 62  RPNWALARLTEKTQRRRL----GPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQT 117

Query: 130 HTMRFLEDAAAPYR-----------------------EQIHKCLKCLRK---EREEIQEI 163
           H M  +++A   YR                       +Q  K LK  R    + +++  +
Sbjct: 118 HAMAPIDEAFESYRTGNFDIHVDEWKRRLIRLLLYHSKQEEKLLKSQRNLVAKMKKVMHL 177

Query: 164 QSRENKRMQVLLTQVSTKRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDL 223
           Q  E K       ++ ++R ++ +EF+ L  FL E++ + L +L  ++ +  ++ +E  L
Sbjct: 178 QDVEVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTL 237

Query: 224 LVAGEICRFSALIEELEEKNERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDF 283
            +   I     LI E+ EK++ P  ELL + +  L R E +     +       + ++  
Sbjct: 238 KLNQTIASLKKLILEVGEKSQAPTLELLQNPKEVLTRSEIQDVNYSL-------EAVKVK 290

Query: 284 PQQALPLQREMKMFLEKLCFELDYEPAHISLDPQTSHPKLLLSEDHQRAQ---------- 333
               +PL +EM          L      ++L   T+HPKL+ S++ +  +          
Sbjct: 291 TVCQIPLMKEM----------LKRFQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPV 340

Query: 334 FSYKWQNSPD--NPQ------RFDRATCVLAHTGITGGRHTWVVSIDLAHGGSCTVGVVS 385
           FS  W       NPQ      RF    CVL     T G+H W   ++        VGV  
Sbjct: 341 FSSAWNYFAGWRNPQKTAFVERFQHLPCVLGKNVFTSGKHYW--EVESRDSLEVAVGVCR 398

Query: 386 EDVQR-KGELRLRPEEGVWAVRLAWGFVSALGSFPTRLTLKEQP-RQVRVSLDYEVGWVT 443
           EDV       ++ P+ G+WA+  +      L  FP   T +E    +V V LD   G V+
Sbjct: 399 EDVMGITDRSKMSPDVGIWAIYWSAAGYWPLIGFPGTPTQQEPALHRVGVYLDRGTGNVS 458

Query: 444 FTNAVTREPIYTFTASFTRKVIPFFGL 470
           F +AV    ++TF+ S   ++ PFF L
Sbjct: 459 FYSAVDGVHLHTFSCSSVSRLRPFFWL 485


>gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens]
          Length = 488

 Score =  194 bits (493), Expect = 1e-49
 Identities = 137/484 (28%), Positives = 239/484 (49%), Gaps = 39/484 (8%)

Query: 7   VTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLCKEPFRP 66
           +  + +EV CPIC   L EP++IDCGH+FC+AC+T          E   +CP+C+  ++P
Sbjct: 6   LVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQP 65

Query: 67  GSFRPNWQLANVVENIERLQLVSTLGLGEE---DVCQEHGEKIYFFCEDDEMQLCVVCRE 123
           G+ RPN  LAN+V  +  +     LG G++    +C +HGEK+  FC++D   +C +C  
Sbjct: 66  GNLRPNRHLANIVRRLREV----VLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCER 121

Query: 124 AGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQVLLTQVSTKRQ 183
           + EH  H    +E+ A  Y+E+  + LK L+ E +E +++ +   ++      Q+  +R 
Sbjct: 122 SQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERC 181

Query: 184 QVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFSALIEELEEKN 243
           ++ +EF  LR  L+  +   L +LE ++   LR  +E +  +  +      LI +LE + 
Sbjct: 182 RIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRC 241

Query: 244 ERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPLQREMKMFLEKLCF 303
           +    ELL D+     R E    RKP A+  +L    R     A  L+R +     ++C 
Sbjct: 242 QGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFR-----APDLKRML-----RVCR 291

Query: 304 ELDYEPAH---ISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDRATCVLAHTGI 360
           EL    ++   ++L+P T++  L+L+++ ++ +F     + P   ++    + VL     
Sbjct: 292 ELTDVQSYWVDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKHYDCS-VLGSQHF 350

Query: 361 TGGRHTWVVSIDLAHGGSCTVGVVSEDV-----------QRKGELRLRPEEGVWAVRLAW 409
           + G+H W   +D+A   +  +GV S  +                 R +P+ G W + L  
Sbjct: 351 SSGKHYW--EVDVAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQH 408

Query: 410 G--FVSALGSFPT-RLTLKEQPRQVRVSLDYEVGWVTFTNAVTRE-PIYTFTA-SFTRKV 464
              + +   S P+  L++   PR+V V LDYE G V+F N      PIYTF+   F   +
Sbjct: 409 NHEYRAYEDSSPSLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTL 468

Query: 465 IPFF 468
            P+F
Sbjct: 469 CPYF 472


>gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens]
          Length = 516

 Score =  194 bits (493), Expect = 1e-49
 Identities = 137/484 (28%), Positives = 239/484 (49%), Gaps = 39/484 (8%)

Query: 7   VTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLCKEPFRP 66
           +  + +EV CPIC   L EP++IDCGH+FC+AC+T          E   +CP+C+  ++P
Sbjct: 34  LVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQP 93

Query: 67  GSFRPNWQLANVVENIERLQLVSTLGLGEE---DVCQEHGEKIYFFCEDDEMQLCVVCRE 123
           G+ RPN  LAN+V  +  +     LG G++    +C +HGEK+  FC++D   +C +C  
Sbjct: 94  GNLRPNRHLANIVRRLREV----VLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCER 149

Query: 124 AGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQVLLTQVSTKRQ 183
           + EH  H    +E+ A  Y+E+  + LK L+ E +E +++ +   ++      Q+  +R 
Sbjct: 150 SQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERC 209

Query: 184 QVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFSALIEELEEKN 243
           ++ +EF  LR  L+  +   L +LE ++   LR  +E +  +  +      LI +LE + 
Sbjct: 210 RIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRC 269

Query: 244 ERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPLQREMKMFLEKLCF 303
           +    ELL D+     R E    RKP A+  +L    R     A  L+R +     ++C 
Sbjct: 270 QGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFR-----APDLKRML-----RVCR 319

Query: 304 ELDYEPAH---ISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDRATCVLAHTGI 360
           EL    ++   ++L+P T++  L+L+++ ++ +F     + P   ++    + VL     
Sbjct: 320 ELTDVQSYWVDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKHYDCS-VLGSQHF 378

Query: 361 TGGRHTWVVSIDLAHGGSCTVGVVSEDV-----------QRKGELRLRPEEGVWAVRLAW 409
           + G+H W   +D+A   +  +GV S  +                 R +P+ G W + L  
Sbjct: 379 SSGKHYW--EVDVAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQH 436

Query: 410 G--FVSALGSFPT-RLTLKEQPRQVRVSLDYEVGWVTFTNAVTRE-PIYTFTA-SFTRKV 464
              + +   S P+  L++   PR+V V LDYE G V+F N      PIYTF+   F   +
Sbjct: 437 NHEYRAYEDSSPSLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTL 496

Query: 465 IPFF 468
            P+F
Sbjct: 497 CPYF 500


>gi|4557743 Mediterranean fever protein [Homo sapiens]
          Length = 781

 Score =  189 bits (480), Expect = 5e-48
 Identities = 134/475 (28%), Positives = 220/475 (46%), Gaps = 44/475 (9%)

Query: 12  DEVNCPICQGTLREPVTIDCGHNFCR--ACLTRYCEIPGPDLEESPTCPLCKEPFR---P 66
           D    P C     +PV   C  + C     ++ + +  G     SP CP C++      P
Sbjct: 308 DTAASPRCHAQEGDPVDGTCVRDSCSFPEAVSGHPQASG---SRSPGCPRCQDSHERKSP 364

Query: 67  GSFRPNWQLANVVENIERLQLVSTLGLGEEDVCQEHGEKIYFFCEDDEMQLCVVCREAGE 126
           GS  P   L     +++++QL+                    FCED +  +C++C  + E
Sbjct: 365 GSLSPQ-PLPQCKRHLKQVQLL--------------------FCEDHDEPICLICSLSQE 403

Query: 127 HATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQVLLTQVSTKRQQVI 186
           H  H +R +E+ A  ++++I K L+ L+K R+  +E +S   ++    L Q    +Q+V 
Sbjct: 404 HQGHRVRPIEEVALEHKKKIQKQLEHLKKLRKSGEEQRSYGEEKAVSFLKQTEALKQRVQ 463

Query: 187 SEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFSALIEELEEKNERP 246
            +   +  FLE+Q+   +A LE     + + R  +D  V+ +I    ALI ELE K  + 
Sbjct: 464 RKLEQVYYFLEQQEHFFVASLEDVGQMVGQIRKAYDTRVSQDIALLDALIGELEAKECQS 523

Query: 247 ARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPLQREMKMFLEKLCFELD 306
             ELL DI   L R +T    +      E+ Q+I+   Q++  +++  K F E L  E++
Sbjct: 524 EWELLQDIGDILHRAKTVPVPEKWTTPQEIKQKIQLLHQKSEFVEKSTKYFSETLRSEME 583

Query: 307 Y-----------EPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDRATCVL 355
                          ++ LD +T++P L+ S+D +  +   KW+  PD PQRFD    VL
Sbjct: 584 MFNVPELIGAQAHAVNVILDAETAYPNLIFSDDLKSVRLGNKWERLPDGPQRFDSCIIVL 643

Query: 356 AHTGITGGRHTWVVSIDLAHGGSCTVGVVSEDVQRKGELRLRPEEGVWAV-RLAWGFVSA 414
                  GR  W   +++    +  +G     + RKG + L PE G W V  +      A
Sbjct: 644 GSPSFLSGRRYW--EVEVGDKTAWILGACKTSISRKGNMTLSPENGYWVVIMMKENEYQA 701

Query: 415 LGSFPTRLTLKEQPRQVRVSLDYEVGWVTFTNAVTREPIYTF-TASFTRKVIPFF 468
               PTRL +KE P++V + +DY VG ++F N   R  IYTF + SF+  + P F
Sbjct: 702 SSVPPTRLLIKEPPKRVGIFVDYRVGSISFYNVTARSHIYTFASCSFSGPLQPIF 756


>gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens]
          Length = 477

 Score =  186 bits (473), Expect = 3e-47
 Identities = 132/479 (27%), Positives = 225/479 (46%), Gaps = 30/479 (6%)

Query: 1   MASAASVTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDL-----EESP 55
           M +      L +E  C IC     +PV   CGHNFCRAC+    E           + S 
Sbjct: 1   MEAVELARKLQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSF 60

Query: 56  TCPLCKEPFRPGSFRPNWQLANVVENIERLQLVSTLGLGEEDVCQEHGEKIYFFCEDDEM 115
            CP C+E     +  PN  L  V E  ++       GL ++D+CQEH E +  FC+ D+ 
Sbjct: 61  PCPECREMSPQRNLLPNRLLTKVAEMAQQHP-----GLQKQDLCQEHHEPLKLFCQKDQS 115

Query: 116 QLCVVCREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQVLL 175
            +CVVCRE+ EH  H +   E+A   Y+ ++ + ++ LR++      +Q+RE + +    
Sbjct: 116 PICVVCRESREHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLAEWQ 175

Query: 176 TQVSTKRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFSAL 235
            +V  +R++++ EF  +  +L E++  LL  LE+++ +   +  E    +  +      L
Sbjct: 176 GKVKERRERIVLEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSLELL 235

Query: 236 IEELEEKNERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPLQREMK 295
           + +LEE++ +   ++L D++  L R      + P    P   + +   P Q       ++
Sbjct: 236 LLQLEERSTQGPLQMLQDMKEPLSRKNNVSVQCPEVAPPTRPRTVCRVPGQI----EVLR 291

Query: 296 MFLEKLCFELDYEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSP-DNPQRFDRATCV 354
            FLE      D  P     D  +++P LLL E  QR       + S   +  RF    C 
Sbjct: 292 GFLE------DVVP-----DATSAYPYLLLYESRQRRYLGSSPEGSGFCSKDRFVAYPCA 340

Query: 355 LAHTGITGGRHTWVVSIDLAHGGSCTVGVVSEDVQRKGELRLRPEEGVWAVRLAWG--FV 412
           +  T  + GRH W V +++       +GV  ++V RK  +   PE G W V+L+ G  ++
Sbjct: 341 VGQTAFSSGRHYWEVGMNITGDALWALGVCRDNVSRKDRVPKCPENGFWVVQLSKGTKYL 400

Query: 413 SALGSFPTRLTLKEQPRQVRVSLDYEVGWVTFTNAVTREPIYTFT-ASFTRKVIPFFGL 470
           S   +  T + L E P  + + LD+E G V+F +      ++T++ A+F   + PFF L
Sbjct: 401 STFSAL-TPVMLMEPPSHMGIFLDFEAGEVSFYSVSDGSHLHTYSQATFPGPLQPFFCL 458


>gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens]
          Length = 477

 Score =  186 bits (473), Expect = 3e-47
 Identities = 132/479 (27%), Positives = 225/479 (46%), Gaps = 30/479 (6%)

Query: 1   MASAASVTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDL-----EESP 55
           M +      L +E  C IC     +PV   CGHNFCRAC+    E           + S 
Sbjct: 1   MEAVELARKLQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSF 60

Query: 56  TCPLCKEPFRPGSFRPNWQLANVVENIERLQLVSTLGLGEEDVCQEHGEKIYFFCEDDEM 115
            CP C+E     +  PN  L  V E  ++       GL ++D+CQEH E +  FC+ D+ 
Sbjct: 61  PCPECREMSPQRNLLPNRLLTKVAEMAQQHP-----GLQKQDLCQEHHEPLKLFCQKDQS 115

Query: 116 QLCVVCREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQVLL 175
            +CVVCRE+ EH  H +   E+A   Y+ ++ + ++ LR++      +Q+RE + +    
Sbjct: 116 PICVVCRESREHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLAEWQ 175

Query: 176 TQVSTKRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFSAL 235
            +V  +R++++ EF  +  +L E++  LL  LE+++ +   +  E    +  +      L
Sbjct: 176 GKVKERRERIVLEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSLELL 235

Query: 236 IEELEEKNERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPLQREMK 295
           + +LEE++ +   ++L D++  L R      + P    P   + +   P Q       ++
Sbjct: 236 LLQLEERSTQGPLQMLQDMKEPLSRKNNVSVQCPEVAPPTRPRTVCRVPGQI----EVLR 291

Query: 296 MFLEKLCFELDYEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSP-DNPQRFDRATCV 354
            FLE      D  P     D  +++P LLL E  QR       + S   +  RF    C 
Sbjct: 292 GFLE------DVVP-----DATSAYPYLLLYESRQRRYLGSSPEGSGFCSKDRFVAYPCA 340

Query: 355 LAHTGITGGRHTWVVSIDLAHGGSCTVGVVSEDVQRKGELRLRPEEGVWAVRLAWG--FV 412
           +  T  + GRH W V +++       +GV  ++V RK  +   PE G W V+L+ G  ++
Sbjct: 341 VGQTAFSSGRHYWEVGMNITGDALWALGVCRDNVSRKDRVPKCPENGFWVVQLSKGTKYL 400

Query: 413 SALGSFPTRLTLKEQPRQVRVSLDYEVGWVTFTNAVTREPIYTFT-ASFTRKVIPFFGL 470
           S   +  T + L E P  + + LD+E G V+F +      ++T++ A+F   + PFF L
Sbjct: 401 STFSAL-TPVMLMEPPSHMGIFLDFEAGEVSFYSVSDGSHLHTYSQATFPGPLQPFFCL 458


>gi|88999601 tripartite motif-containing 69 isoform a [Homo sapiens]
          Length = 500

 Score =  185 bits (469), Expect = 9e-47
 Identities = 141/477 (29%), Positives = 228/477 (47%), Gaps = 31/477 (6%)

Query: 1   MASAASVTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLC 60
           + S   +  +  E++CP+C    R+P+ + CGHNFC AC+  +  +      +   CP C
Sbjct: 26  LPSKVVIQDITMELHCPLCNDWFRDPLMLSCGHNFCEACIQDFWRLQA----KETFCPEC 81

Query: 61  KEPFRPGSFRPNWQLANVVENIERLQLVSTLGLGEEDVCQEHGEKIYFFCEDDEMQLCVV 120
           K   +  +   N  L  +VE I++L L     L     C EHGE +  F + D   +C  
Sbjct: 82  KMLCQYNNCTFNPVLDKLVEKIKKLPL-----LKGHPQCPEHGENLKLFSKPDGKLICFQ 136

Query: 121 CREAGEHATHTMRFLE--DAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQVLLTQV 178
           C++A      +  FL+  DA   + E++      L    +E+Q +++ + + +       
Sbjct: 137 CKDARLSVGQSKEFLQISDAVHFFTEELAIQQGQLETTLKELQTLRNMQKEAIAAHKENK 196

Query: 179 STKRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFSA-LIE 237
              +Q V  EF  L +FL  ++  +L +L  ++G  L +  E +L    E C  +  ++ 
Sbjct: 197 LHLQQHVSMEFLKLHQFLHSKEKDILTELR-EEGKALNEEMELNLSQLQEQCLLAKDMLV 255

Query: 238 ELEEKNERP-ARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPLQ----R 292
            ++ K E+  + + L DI + L   E       V  + EL  R  +  Q   P+Q    R
Sbjct: 256 SIQAKTEQQNSFDFLKDITTLLHSLEQ---GMKVLATRELISRKLNLGQYKGPIQYMVWR 312

Query: 293 EMKMFLEKLCFELDYEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDRAT 352
           EM+   + LC  L    + ++LDP+T+HP L+LS+           +  PD+P+RFD + 
Sbjct: 313 EMQ---DTLCPGL----SPLTLDPKTAHPNLVLSKSQTSVWHGDIKKIMPDDPERFDSSV 365

Query: 353 CVLAHTGITGGRHTWVVSIDLAHGGSCTVGVVSEDVQRKGELRLRPEEGVWAVRLA-WGF 411
            VL   G T G+  W   +++A     TVGVV E + RKG   L PE+G W +RL     
Sbjct: 366 AVLGSRGFTSGK--WYWEVEVAKKTKWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTD 423

Query: 412 VSALGSFPTRLTLKEQPRQVRVSLDYEVGWVTFTNAVTREPIYTFTASFTRKVIPFF 468
           + AL      LTL     +V + LDYE G ++F NA T   IYTF+ +F  K+ P+F
Sbjct: 424 LKALDLPSFSLTLTNNLDKVGIYLDYEGGQLSFYNAKTMTHIYTFSNTFMEKLYPYF 480


>gi|62865604 tripartite motif protein 31 [Homo sapiens]
          Length = 425

 Score =  177 bits (449), Expect = 2e-44
 Identities = 98/301 (32%), Positives = 162/301 (53%), Gaps = 4/301 (1%)

Query: 1   MASAASVTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLC 60
           MAS   V  L +EV CPIC   L++PVTIDCGHNFC  C+T+  E      +    CPLC
Sbjct: 1   MASGQFVNKLQEEVICPICLDILQKPVTIDCGHNFCLKCITQIGETSCGFFK----CPLC 56

Query: 61  KEPFRPGSFRPNWQLANVVENIERLQLVSTLGLGEEDVCQEHGEKIYFFCEDDEMQLCVV 120
           K   R  + R N  L N+VE I+ LQ        +E  C  H E  ++FCEDD   LC V
Sbjct: 57  KTSVRKNAIRFNSLLRNLVEKIQALQASEVQSKRKEATCPRHQEMFHYFCEDDGKFLCFV 116

Query: 121 CREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQVLLTQVST 180
           CRE+ +H +H +  +E+AA  Y+ QI + ++ L+++ +E  +++++   R+ V   QV  
Sbjct: 117 CRESKDHKSHNVSLIEEAAQNYQGQIQEQIQVLQQKEKETVQVKAQGVHRVDVFTDQVEH 176

Query: 181 KRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFSALIEELE 240
           ++Q++++EF  L + LEE+++ LL+++     +       +      ++     L++ L+
Sbjct: 177 EKQRILTEFELLHQVLEEEKNFLLSRIYWLGHEGTEAGKHYVASTEPQLNDLKKLVDSLK 236

Query: 241 EKNERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPLQREMKMFLEK 300
            K   P R+LL DI+  L R E  +   P  V  EL +++ +   +   +   +K F ++
Sbjct: 237 TKQNMPPRQLLEDIKVVLCRSEEFQFLNPTPVPLELEKKLSEAKSRHDSITGSLKKFKDQ 296

Query: 301 L 301
           L
Sbjct: 297 L 297


>gi|42516574 tripartite motif-containing 41 isoform 2 [Homo sapiens]
          Length = 518

 Score =  176 bits (446), Expect = 4e-44
 Identities = 105/324 (32%), Positives = 173/324 (53%), Gaps = 11/324 (3%)

Query: 47  PGPDLEESPTCPLCKEPFRPGSFRPNWQLANVVENIERLQLVSTLG--LGEEDVCQEHGE 104
           P P      TCP C++ F   SFRPN QLAN+V+ I ++      G  + ++ +C +H E
Sbjct: 173 PPPAPRRCFTCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQE 232

Query: 105 KIYFFCEDDEMQLCVVCREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQ 164
            +  FCE DE  +CVVCRE+  H  H++  LE+    Y+ ++   ++ LRK  E +Q+++
Sbjct: 233 ALKLFCEVDEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMK 292

Query: 165 SRENKRMQVLLTQVSTKRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLL 224
           ++E +R+  L +Q+ ++   V SEF  L +FL E+Q+ L  +L       L +       
Sbjct: 293 AKEERRVTELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASR 352

Query: 225 VAGEICRFSALIEELEEKNERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQ-RIRDF 283
           +A +  + S L+ E +E++++    LL DI+ T  RCE  + + P   SP+  Q    DF
Sbjct: 353 LAEQAAQLSRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDPCQPHSHDF 412

Query: 284 PQQALPLQREMKMFLEKLCFELDYEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPD 343
              A+ +++  +MF +    +L       +LDP T+HP L+LS D +  + + + Q   D
Sbjct: 413 LTDAI-VRKMSRMFCQAARVDL-------TLDPDTAHPALMLSPDRRGVRLAERRQEVAD 464

Query: 344 NPQRFDRATCVLAHTGITGGRHTW 367
           +P+RF    CVL   G   GRH W
Sbjct: 465 HPKRFSADCCVLGAQGFRSGRHYW 488



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 18/36 (50%), Positives = 24/36 (66%)

Query: 7  VTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTR 42
          V +L +E  C IC     +PV+I CGHNFCR C+T+
Sbjct: 11 VQTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQ 46


>gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens]
          Length = 488

 Score =  173 bits (439), Expect = 3e-43
 Identities = 137/488 (28%), Positives = 228/488 (46%), Gaps = 45/488 (9%)

Query: 9   SLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLCKEPFRPGS 68
           ++ +EV CPIC   L EP+++DCGH+ CRAC+T   +     +    +CP+C   +    
Sbjct: 8   NVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSFEH 67

Query: 69  FRPNWQLANVVENIERLQLVSTLGLGEEDVCQEHGEKIYFFCEDDEMQLCVVCREAGEHA 128
            + N  LAN+VE ++ ++L    G  + D+C  HGEK+  FC++D   +C +C  + EH 
Sbjct: 68  LQANQHLANIVERLKEVKLSPDNGK-KRDLCDHHGEKLLLFCKEDRKVICWLCERSQEHR 126

Query: 129 THTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQVLLTQVSTKRQQVISE 188
            H     E+     +E++   LK L+KE EE +++++   +       QV T+RQ++ +E
Sbjct: 127 GHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQRIQTE 186

Query: 189 FAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFSALIEELEEKNERPAR 248
           F  LR  L  ++   L +LE ++   L +  E +  +  +      LI ++E +++    
Sbjct: 187 FDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECRSQWSTM 246

Query: 249 ELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPLQREMKMFLEKL---CFEL 305
           ELL D+   +   E  + +KP  VS +L          A  L R ++MF E     C+ +
Sbjct: 247 ELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVF-----HAPDLSRMLQMFRELTAVRCYWV 301

Query: 306 DYEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDRATCVLAHTGITGGRH 365
           D     ++L+    +  L+LSED ++      W     N         VL     + G+H
Sbjct: 302 D-----VTLNSVNLNLNLVLSEDQRQVISVPIWPFQCYN-------YGVLGSQYFSSGKH 349

Query: 366 TWVVSIDLAHGGSCTVGVVSEDVQRKGE-------------LRLRPEEGVWAVRL----A 408
            W   +D++   +  +GV      R  +              + RP  G W + L     
Sbjct: 350 YW--EVDVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCK 407

Query: 409 WG-FVSALGSFPTRLTLK--EQPRQVRVSLDYEVGWVTFTNAVTR-EPIYTFT-ASFTRK 463
           +G F  +L S P  LTL     P +V V LDYE G V+F N  +    IY F+   F++ 
Sbjct: 408 YGVFEESLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQP 467

Query: 464 VIPFFGLW 471
           V P+F  W
Sbjct: 468 VYPYFNPW 475


>gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens]
          Length = 488

 Score =  173 bits (439), Expect = 3e-43
 Identities = 137/488 (28%), Positives = 228/488 (46%), Gaps = 45/488 (9%)

Query: 9   SLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLCKEPFRPGS 68
           ++ +EV CPIC   L EP+++DCGH+ CRAC+T   +     +    +CP+C   +    
Sbjct: 8   NVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSFEH 67

Query: 69  FRPNWQLANVVENIERLQLVSTLGLGEEDVCQEHGEKIYFFCEDDEMQLCVVCREAGEHA 128
            + N  LAN+VE ++ ++L    G  + D+C  HGEK+  FC++D   +C +C  + EH 
Sbjct: 68  LQANQHLANIVERLKEVKLSPDNGK-KRDLCDHHGEKLLLFCKEDRKVICWLCERSQEHR 126

Query: 129 THTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQVLLTQVSTKRQQVISE 188
            H     E+     +E++   LK L+KE EE +++++   +       QV T+RQ++ +E
Sbjct: 127 GHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQRIQTE 186

Query: 189 FAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFSALIEELEEKNERPAR 248
           F  LR  L  ++   L +LE ++   L +  E +  +  +      LI ++E +++    
Sbjct: 187 FDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECRSQWSTM 246

Query: 249 ELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPLQREMKMFLEKL---CFEL 305
           ELL D+   +   E  + +KP  VS +L          A  L R ++MF E     C+ +
Sbjct: 247 ELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVF-----HAPDLSRMLQMFRELTAVRCYWV 301

Query: 306 DYEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDRATCVLAHTGITGGRH 365
           D     ++L+    +  L+LSED ++      W     N         VL     + G+H
Sbjct: 302 D-----VTLNSVNLNLNLVLSEDQRQVISVPIWPFQCYN-------YGVLGSQYFSSGKH 349

Query: 366 TWVVSIDLAHGGSCTVGVVSEDVQRKGE-------------LRLRPEEGVWAVRL----A 408
            W   +D++   +  +GV      R  +              + RP  G W + L     
Sbjct: 350 YW--EVDVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCK 407

Query: 409 WG-FVSALGSFPTRLTLK--EQPRQVRVSLDYEVGWVTFTNAVTR-EPIYTFT-ASFTRK 463
           +G F  +L S P  LTL     P +V V LDYE G V+F N  +    IY F+   F++ 
Sbjct: 408 YGVFEESLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQP 467

Query: 464 VIPFFGLW 471
           V P+F  W
Sbjct: 468 VYPYFNPW 475


>gi|51477690 tripartite motif-containing 6 and tripartite
           motif-containing 34 [Homo sapiens]
          Length = 842

 Score =  173 bits (439), Expect = 3e-43
 Identities = 137/488 (28%), Positives = 228/488 (46%), Gaps = 45/488 (9%)

Query: 9   SLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLCKEPFRPGS 68
           ++ +EV CPIC   L EP+++DCGH+ CRAC+T   +     +    +CP+C   +    
Sbjct: 362 NVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSFEH 421

Query: 69  FRPNWQLANVVENIERLQLVSTLGLGEEDVCQEHGEKIYFFCEDDEMQLCVVCREAGEHA 128
            + N  LAN+VE ++ ++L    G  + D+C  HGEK+  FC++D   +C +C  + EH 
Sbjct: 422 LQANQHLANIVERLKEVKLSPDNGK-KRDLCDHHGEKLLLFCKEDRKVICWLCERSQEHR 480

Query: 129 THTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQVLLTQVSTKRQQVISE 188
            H     E+     +E++   LK L+KE EE +++++   +       QV T+RQ++ +E
Sbjct: 481 GHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQRIQTE 540

Query: 189 FAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFSALIEELEEKNERPAR 248
           F  LR  L  ++   L +LE ++   L +  E +  +  +      LI ++E +++    
Sbjct: 541 FDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECRSQWSTM 600

Query: 249 ELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPLQREMKMFLEKL---CFEL 305
           ELL D+   +   E  + +KP  VS +L          A  L R ++MF E     C+ +
Sbjct: 601 ELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVF-----HAPDLSRMLQMFRELTAVRCYWV 655

Query: 306 DYEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDRATCVLAHTGITGGRH 365
           D     ++L+    +  L+LSED ++      W     N         VL     + G+H
Sbjct: 656 D-----VTLNSVNLNLNLVLSEDQRQVISVPIWPFQCYN-------YGVLGSQYFSSGKH 703

Query: 366 TWVVSIDLAHGGSCTVGVVSEDVQRKGE-------------LRLRPEEGVWAVRL----A 408
            W   +D++   +  +GV      R  +              + RP  G W + L     
Sbjct: 704 YW--EVDVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCK 761

Query: 409 WG-FVSALGSFPTRLTLK--EQPRQVRVSLDYEVGWVTFTNAVTR-EPIYTFT-ASFTRK 463
           +G F  +L S P  LTL     P +V V LDYE G V+F N  +    IY F+   F++ 
Sbjct: 762 YGVFEESLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQP 821

Query: 464 VIPFFGLW 471
           V P+F  W
Sbjct: 822 VYPYFNPW 829



 Score =  155 bits (392), Expect = 8e-38
 Identities = 86/278 (30%), Positives = 146/278 (52%), Gaps = 7/278 (2%)

Query: 7   VTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLCKEPFRP 66
           +  + +EV CPIC   L EP++IDCGH+FC+AC+T          E   +CP+C+  ++P
Sbjct: 34  LVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQP 93

Query: 67  GSFRPNWQLANVVENIERLQLVSTLGLGEE---DVCQEHGEKIYFFCEDDEMQLCVVCRE 123
           G+ RPN  LAN+V  +  +     LG G++    +C +HGEK+  FC++D   +C +C  
Sbjct: 94  GNLRPNRHLANIVRRLREV----VLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCER 149

Query: 124 AGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQVLLTQVSTKRQ 183
           + EH  H    +E+ A  Y+E+  + LK L+ E +E +++ +   ++      Q+  +R 
Sbjct: 150 SQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERC 209

Query: 184 QVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFSALIEELEEKN 243
           ++ +EF  LR  L+  +   L +LE ++   LR  +E +  +  +      LI +LE + 
Sbjct: 210 RIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRC 269

Query: 244 ERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIR 281
           +    ELL D+     R E    RKP A+  +L    R
Sbjct: 270 QGSTMELLQDVSDVTERSEFWTLRKPEALPTKLRSMFR 307


>gi|117938316 tripartite motif-containing 22 [Homo sapiens]
          Length = 498

 Score =  173 bits (438), Expect = 4e-43
 Identities = 130/485 (26%), Positives = 227/485 (46%), Gaps = 37/485 (7%)

Query: 13  EVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLCKEPFRPGSFRPN 72
           EV CPIC   L EP+++DCGH+FC+AC+T   +          +CP+C+  F+PG+ RPN
Sbjct: 12  EVTCPICLELLTEPLSLDCGHSFCQACITAKIKESVIISRGESSCPVCQTRFQPGNLRPN 71

Query: 73  WQLANVVENIERLQLVSTLGLGEEDVCQEHGEKIYFFCEDDEMQLCVVCREAGEHATHTM 132
             LAN+VE ++ +++    G  + DVC+ HG+K+  FC++D   +C VC  + EH  H  
Sbjct: 72  RHLANIVERVKEVKMSPQEGQ-KRDVCEHHGKKLQIFCKEDGKVICWVCELSQEHQGHQT 130

Query: 133 RFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQVLLTQVSTKRQQVISEFAHL 192
             + +     +E++   L+ L KE +E ++++    +        +  +RQ+++  F  +
Sbjct: 131 FRINEVVKECQEKLQVALQRLIKEDQEAEKLEDDIRQERTAWKNYIQIERQKILKGFNEM 190

Query: 193 RKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFSALIEELEEKNERPARELLT 252
           R  L+ ++   L +LE  + ++L         +  +    S LI +L+ +    + E+L 
Sbjct: 191 RVILDNEEQRELQKLEEGEVNVLDNLAAATDQLVQQRQDASTLISDLQRRLRGSSVEMLQ 250

Query: 253 DIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPLQREMKMFLEKLCFELDYEPAHI 312
           D+   + R E+   +KP +VS +L    R      +P    M   L++L  ++ Y    +
Sbjct: 251 DVIDVMKRSESWTLKKPKSVSKKLKSVFR------VPDLSGMLQVLKELT-DVQYYWVDV 303

Query: 313 SLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDRATCVLAHTGITGGRHTWVVSID 372
            L+P ++   + +S D ++ +          NP  F  A  V      + G++ W   +D
Sbjct: 304 MLNPGSATSNVAISVDQRQVKTVRTCTFKNSNPCDFS-AFGVFGCQYFSSGKYYW--EVD 360

Query: 373 LAHGGSCTVGV---VSEDVQRKGE--------------LRLRPEEGVWAVRLA-----WG 410
           ++   +  +GV   +S   +RK                 R RP+ G W + L        
Sbjct: 361 VSGKIAWILGVHSKISSLNKRKSSGFAFDPSVNYSKVYSRYRPQYGYWVIGLQNTCEYNA 420

Query: 411 FVSALGSFPTRLTL--KEQPRQVRVSLDYEVGWVTFTNAVTREP-IYTFT-ASFTRKVIP 466
           F  +  S P  LTL     P ++ V LDYE G V+F N       IY F+   F+R   P
Sbjct: 421 FEDSSSSDPKVLTLFMAVPPCRIGVFLDYEAGIVSFFNVTNHGALIYKFSGCRFSRPAYP 480

Query: 467 FFGLW 471
           +F  W
Sbjct: 481 YFNPW 485


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.418 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,719,657
Number of Sequences: 37866
Number of extensions: 954478
Number of successful extensions: 4790
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 239
Number of HSP's successfully gapped in prelim test: 292
Number of HSP's that attempted gapping in prelim test: 3778
Number of HSP's gapped (non-prelim): 903
length of query: 481
length of database: 18,247,518
effective HSP length: 106
effective length of query: 375
effective length of database: 14,233,722
effective search space: 5337645750
effective search space used: 5337645750
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.