BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|157426845 protocadherin 19 isoform b [Homo sapiens] (1100 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|157426845 protocadherin 19 isoform b [Homo sapiens] 2189 0.0 gi|157426847 protocadherin 19 isoform a [Homo sapiens] 2184 0.0 gi|94538350 protocadherin 17 precursor [Homo sapiens] 977 0.0 gi|14589916 protocadherin 10 isoform 1 precursor [Homo sapiens] 724 0.0 gi|14589914 protocadherin 10 isoform 2 precursor [Homo sapiens] 657 0.0 gi|14589929 protocadherin 18 precursor [Homo sapiens] 635 0.0 gi|9256600 protocadherin alpha subfamily C, 2 isoform 1 precurso... 543 e-154 gi|14165431 protocadherin alpha subfamily C, 2 isoform 2 precurs... 543 e-154 gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens] 494 e-139 gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo sapi... 494 e-139 gi|14196468 protocadherin gamma subfamily A, 4 isoform 2 precurs... 492 e-139 gi|11056026 protocadherin gamma subfamily A, 4 isoform 1 precurs... 492 e-139 gi|14277682 protocadherin gamma subfamily C, 4 isoform 2 precurs... 492 e-139 gi|11128025 protocadherin gamma subfamily C, 4 isoform 1 precurs... 492 e-139 gi|14165413 protocadherin alpha 4 isoform 2 precursor [Homo sapi... 489 e-138 gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens] 489 e-138 gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo sapi... 489 e-138 gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens] 489 e-138 gi|14165390 protocadherin alpha 6 isoform 2 precursor [Homo sapi... 488 e-137 gi|9256592 protocadherin alpha 6 isoform 1 precursor [Homo sapiens] 488 e-137 gi|14165419 protocadherin alpha 7 isoform 2 precursor [Homo sapi... 486 e-137 gi|9256594 protocadherin alpha 7 isoform 1 precursor [Homo sapiens] 486 e-137 gi|11128035 protocadherin gamma subfamily B, 2 isoform 1 precurs... 486 e-137 gi|14270493 protocadherin gamma subfamily B, 2 isoform 2 precurs... 486 e-137 gi|7706113 protocadherin 12 precursor [Homo sapiens] 485 e-137 gi|14165387 protocadherin alpha 11 isoform 2 precursor [Homo sap... 483 e-136 gi|9256576 protocadherin alpha 11 isoform 1 precursor [Homo sapi... 483 e-136 gi|14165397 protocadherin alpha 13 isoform 2 precursor [Homo sap... 483 e-136 gi|9256580 protocadherin alpha 13 isoform 1 precursor [Homo sapi... 483 e-136 gi|14277685 protocadherin gamma subfamily C, 5 isoform 2 precurs... 481 e-135 >gi|157426845 protocadherin 19 isoform b [Homo sapiens] Length = 1100 Score = 2189 bits (5672), Expect = 0.0 Identities = 1100/1100 (100%), Positives = 1100/1100 (100%) Query: 1 MESLLLPVLLLLAILWTQAAALINLKYSVEEEQRAGTVIANVAKDAREAGFALDPRQASA 60 MESLLLPVLLLLAILWTQAAALINLKYSVEEEQRAGTVIANVAKDAREAGFALDPRQASA Sbjct: 1 MESLLLPVLLLLAILWTQAAALINLKYSVEEEQRAGTVIANVAKDAREAGFALDPRQASA 60 Query: 61 FRVVSNSAPHLVDINPSSGLLVTKQKIDRDLLCRQSPKCIISLEVMSSSMEICVIKVEIK 120 FRVVSNSAPHLVDINPSSGLLVTKQKIDRDLLCRQSPKCIISLEVMSSSMEICVIKVEIK Sbjct: 61 FRVVSNSAPHLVDINPSSGLLVTKQKIDRDLLCRQSPKCIISLEVMSSSMEICVIKVEIK 120 Query: 121 DLNDNAPSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKT 180 DLNDNAPSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKT Sbjct: 121 DLNDNAPSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKT 180 Query: 181 RGDGSRFAELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNPVFSE 240 RGDGSRFAELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNPVFSE Sbjct: 181 RGDGSRFAELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNPVFSE 240 Query: 241 STYAVSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTV 300 STYAVSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTV Sbjct: 241 STYAVSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTV 300 Query: 301 TGALDYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSE 360 TGALDYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSE Sbjct: 301 TGALDYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSE 360 Query: 361 SAPPGYVIALVRVSDRDSGLNGRVQCRLLGNVPFRLQEYESFSTILVDGRLDREQHDQYN 420 SAPPGYVIALVRVSDRDSGLNGRVQCRLLGNVPFRLQEYESFSTILVDGRLDREQHDQYN Sbjct: 361 SAPPGYVIALVRVSDRDSGLNGRVQCRLLGNVPFRLQEYESFSTILVDGRLDREQHDQYN 420 Query: 421 LTIQARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDP 480 LTIQARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDP Sbjct: 421 LTIQARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDP 480 Query: 481 DLGLNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGGL 540 DLGLNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGGL Sbjct: 481 DLGLNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGGL 540 Query: 541 PSLQSNATVRVIILDVNDNTPVITAPPLINGTAEVYIPRNSGIGYLVTVVKAEDYDEGEN 600 PSLQSNATVRVIILDVNDNTPVITAPPLINGTAEVYIPRNSGIGYLVTVVKAEDYDEGEN Sbjct: 541 PSLQSNATVRVIILDVNDNTPVITAPPLINGTAEVYIPRNSGIGYLVTVVKAEDYDEGEN 600 Query: 601 GRVTYDMTEGDRGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGKTSLSASALVLI 660 GRVTYDMTEGDRGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGKTSLSASALVLI Sbjct: 601 GRVTYDMTEGDRGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGKTSLSASALVLI 660 Query: 661 YLSPALDAQESMGSVNLSLIFIIALGSIAGILFVTMIFVAIKCKRDNKEIRTYNCRIAEY 720 YLSPALDAQESMGSVNLSLIFIIALGSIAGILFVTMIFVAIKCKRDNKEIRTYNCRIAEY Sbjct: 661 YLSPALDAQESMGSVNLSLIFIIALGSIAGILFVTMIFVAIKCKRDNKEIRTYNCRIAEY 720 Query: 721 SYGHQKKSSKKKKISKNDIRLVPRDVEETDKMNVVSCSSLTSSLNYFDYHQQTLPLGCRR 780 SYGHQKKSSKKKKISKNDIRLVPRDVEETDKMNVVSCSSLTSSLNYFDYHQQTLPLGCRR Sbjct: 721 SYGHQKKSSKKKKISKNDIRLVPRDVEETDKMNVVSCSSLTSSLNYFDYHQQTLPLGCRR 780 Query: 781 SESTFLNVENQNTRNTSANHIYHHSFNSQGPQQPDLIINGVPLPETENYSFDSNYVNSRA 840 SESTFLNVENQNTRNTSANHIYHHSFNSQGPQQPDLIINGVPLPETENYSFDSNYVNSRA Sbjct: 781 SESTFLNVENQNTRNTSANHIYHHSFNSQGPQQPDLIINGVPLPETENYSFDSNYVNSRA 840 Query: 841 HLIKSSTFKDLEGNSLKDSGHEESDQTDSEHDVQRSLYCDTAVNDVLNTSVTSMGSQMPD 900 HLIKSSTFKDLEGNSLKDSGHEESDQTDSEHDVQRSLYCDTAVNDVLNTSVTSMGSQMPD Sbjct: 841 HLIKSSTFKDLEGNSLKDSGHEESDQTDSEHDVQRSLYCDTAVNDVLNTSVTSMGSQMPD 900 Query: 901 HDQNEGFHCREECRILGHSDRCWMPRNPMPIRSKSPEHVRNIIALSIEATAADVEAYDDC 960 HDQNEGFHCREECRILGHSDRCWMPRNPMPIRSKSPEHVRNIIALSIEATAADVEAYDDC Sbjct: 901 HDQNEGFHCREECRILGHSDRCWMPRNPMPIRSKSPEHVRNIIALSIEATAADVEAYDDC 960 Query: 961 GPTKRTFATFGKDVSDHPAEERPTLKGKRTVDVTICSPKVNSVIREAGNGCEAISPVTSP 1020 GPTKRTFATFGKDVSDHPAEERPTLKGKRTVDVTICSPKVNSVIREAGNGCEAISPVTSP Sbjct: 961 GPTKRTFATFGKDVSDHPAEERPTLKGKRTVDVTICSPKVNSVIREAGNGCEAISPVTSP 1020 Query: 1021 LHLKSSLPTKPSVSYTIALAPPARDLEQYVNNVNNGPTRPSEAEPRGADSEKVMHEVSPI 1080 LHLKSSLPTKPSVSYTIALAPPARDLEQYVNNVNNGPTRPSEAEPRGADSEKVMHEVSPI Sbjct: 1021 LHLKSSLPTKPSVSYTIALAPPARDLEQYVNNVNNGPTRPSEAEPRGADSEKVMHEVSPI 1080 Query: 1081 LKEGRNKESPGVKRLKDIVL 1100 LKEGRNKESPGVKRLKDIVL Sbjct: 1081 LKEGRNKESPGVKRLKDIVL 1100 >gi|157426847 protocadherin 19 isoform a [Homo sapiens] Length = 1101 Score = 2184 bits (5660), Expect = 0.0 Identities = 1100/1101 (99%), Positives = 1100/1101 (99%), Gaps = 1/1101 (0%) Query: 1 MESLLLPVLLLLAILWTQAAALINLKYSVEEEQRAGTVIANVAKDAREAGFALDPRQASA 60 MESLLLPVLLLLAILWTQAAALINLKYSVEEEQRAGTVIANVAKDAREAGFALDPRQASA Sbjct: 1 MESLLLPVLLLLAILWTQAAALINLKYSVEEEQRAGTVIANVAKDAREAGFALDPRQASA 60 Query: 61 FRVVSNSAPHLVDINPSSGLLVTKQKIDRDLLCRQSPKCIISLEVMSSSMEICVIKVEIK 120 FRVVSNSAPHLVDINPSSGLLVTKQKIDRDLLCRQSPKCIISLEVMSSSMEICVIKVEIK Sbjct: 61 FRVVSNSAPHLVDINPSSGLLVTKQKIDRDLLCRQSPKCIISLEVMSSSMEICVIKVEIK 120 Query: 121 DLNDNAPSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKT 180 DLNDNAPSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKT Sbjct: 121 DLNDNAPSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKT 180 Query: 181 RGDGSRFAELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNPVFSE 240 RGDGSRFAELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNPVFSE Sbjct: 181 RGDGSRFAELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNPVFSE 240 Query: 241 STYAVSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTV 300 STYAVSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTV Sbjct: 241 STYAVSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTV 300 Query: 301 TGALDYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSE 360 TGALDYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSE Sbjct: 301 TGALDYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSE 360 Query: 361 SAPPGYVIALVRVSDRDSGLNGRVQCRLLGNVPFRLQEYESFSTILVDGRLDREQHDQYN 420 SAPPGYVIALVRVSDRDSGLNGRVQCRLLGNVPFRLQEYESFSTILVDGRLDREQHDQYN Sbjct: 361 SAPPGYVIALVRVSDRDSGLNGRVQCRLLGNVPFRLQEYESFSTILVDGRLDREQHDQYN 420 Query: 421 LTIQARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDP 480 LTIQARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDP Sbjct: 421 LTIQARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDP 480 Query: 481 DLGLNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGGL 540 DLGLNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGGL Sbjct: 481 DLGLNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGGL 540 Query: 541 PSLQSNATVRVIILDVNDNTPVITAPPLINGTAEVYIPRNSGIGYLVTVVKAEDYDEGEN 600 PSLQSNATVRVIILDVNDNTPVITAPPLINGTAEVYIPRNSGIGYLVTVVKAEDYDEGEN Sbjct: 541 PSLQSNATVRVIILDVNDNTPVITAPPLINGTAEVYIPRNSGIGYLVTVVKAEDYDEGEN 600 Query: 601 GRVTYDMTEGDRGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGKTSLSASALVLI 660 GRVTYDMTEGDRGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGKTSLSASALVLI Sbjct: 601 GRVTYDMTEGDRGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGKTSLSASALVLI 660 Query: 661 YLSPALDAQESMGSVNLSLIFIIALGSIAGILFVTMIFVAIKCKRDNKEIRTYNCRIAEY 720 YLSPALDAQESMGSVNLSLIFIIALGSIAGILFVTMIFVAIKCKRDNKEIRTYNCRIAEY Sbjct: 661 YLSPALDAQESMGSVNLSLIFIIALGSIAGILFVTMIFVAIKCKRDNKEIRTYNCRIAEY 720 Query: 721 SYGHQKKSSKKKKISKNDIRLVPRDVEETDKMNVVSCSSLTSSLNYFDYHQQTLPLGCRR 780 SYGHQKKSSKKKKISKNDIRLVPRDVEETDKMNVVSCSSLTSSLNYFDYHQQTLPLGCRR Sbjct: 721 SYGHQKKSSKKKKISKNDIRLVPRDVEETDKMNVVSCSSLTSSLNYFDYHQQTLPLGCRR 780 Query: 781 SESTFLNVENQNTRNTSANHIYHHSFNSQGPQQPDLIINGVPLPETENYSFDSNYVNSRA 840 SESTFLNVENQNTRNTSANHIYHHSFNSQGPQQPDLIINGVPLPETENYSFDSNYVNSRA Sbjct: 781 SESTFLNVENQNTRNTSANHIYHHSFNSQGPQQPDLIINGVPLPETENYSFDSNYVNSRA 840 Query: 841 HLIK-SSTFKDLEGNSLKDSGHEESDQTDSEHDVQRSLYCDTAVNDVLNTSVTSMGSQMP 899 HLIK SSTFKDLEGNSLKDSGHEESDQTDSEHDVQRSLYCDTAVNDVLNTSVTSMGSQMP Sbjct: 841 HLIKSSSTFKDLEGNSLKDSGHEESDQTDSEHDVQRSLYCDTAVNDVLNTSVTSMGSQMP 900 Query: 900 DHDQNEGFHCREECRILGHSDRCWMPRNPMPIRSKSPEHVRNIIALSIEATAADVEAYDD 959 DHDQNEGFHCREECRILGHSDRCWMPRNPMPIRSKSPEHVRNIIALSIEATAADVEAYDD Sbjct: 901 DHDQNEGFHCREECRILGHSDRCWMPRNPMPIRSKSPEHVRNIIALSIEATAADVEAYDD 960 Query: 960 CGPTKRTFATFGKDVSDHPAEERPTLKGKRTVDVTICSPKVNSVIREAGNGCEAISPVTS 1019 CGPTKRTFATFGKDVSDHPAEERPTLKGKRTVDVTICSPKVNSVIREAGNGCEAISPVTS Sbjct: 961 CGPTKRTFATFGKDVSDHPAEERPTLKGKRTVDVTICSPKVNSVIREAGNGCEAISPVTS 1020 Query: 1020 PLHLKSSLPTKPSVSYTIALAPPARDLEQYVNNVNNGPTRPSEAEPRGADSEKVMHEVSP 1079 PLHLKSSLPTKPSVSYTIALAPPARDLEQYVNNVNNGPTRPSEAEPRGADSEKVMHEVSP Sbjct: 1021 PLHLKSSLPTKPSVSYTIALAPPARDLEQYVNNVNNGPTRPSEAEPRGADSEKVMHEVSP 1080 Query: 1080 ILKEGRNKESPGVKRLKDIVL 1100 ILKEGRNKESPGVKRLKDIVL Sbjct: 1081 ILKEGRNKESPGVKRLKDIVL 1101 >gi|94538350 protocadherin 17 precursor [Homo sapiens] Length = 1159 Score = 977 bits (2526), Expect = 0.0 Identities = 541/1062 (50%), Positives = 706/1062 (66%), Gaps = 54/1062 (5%) Query: 14 ILWTQAAALINLKYSVEEEQRAGTVIANVAKDAR-EAGFALDPR------QASAFRVVSN 66 +LW A L NL YSV EEQ AGTVI N+ +DAR + G R ++ ++RV+ N Sbjct: 10 LLWAPALTLKNLNYSVPEEQGAGTVIGNIGRDARLQPGLPPAERGGGGRSKSGSYRVLEN 69 Query: 67 SAPHLVDINPSSGLLVTKQKIDRDLLCRQSPKCIISLEVMSSSMEICVIKVEIKDLNDNA 126 SAPHL+D++ SGLL TKQ+IDR+ LCR + KC +SLEV ++ EIC+IKVEI+D+NDNA Sbjct: 70 SAPHLLDVDADSGLLYTKQRIDRESLCRHNAKCQLSLEVFANDKEICMIKVEIQDINDNA 129 Query: 127 PSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNE--LFGLEIKTRGDG 184 PSF + QIE++ISE A+PGTR PL SA+DPD+G G++TY LT ++ LFGL++K+RGDG Sbjct: 130 PSFSSDQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHGLFGLDVKSRGDG 189 Query: 185 SRFAELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNPVFSESTYA 244 ++F ELV++K+LDRE Q+H++ +TALDGG+PPR TV +++KV DSNDN+PVF +Y Sbjct: 190 TKFPELVIQKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNSPVFEAPSYL 249 Query: 245 VSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTVTGAL 304 V +PEN+P T VI LNA+D DEG NG+V+YSF YV DR RELF IDP +GL+ V G L Sbjct: 250 VELPENAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDRVRELFSIDPKTGLIRVKGNL 309 Query: 305 DYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSESAPP 364 DYEE + E+DVQA+DLGPN IPAHCKVTV ++D NDN P I +SV +SE+APP Sbjct: 310 DYEENGMLEIDVQARDLGPNPIPAHCKVTVKLIDRNDNAPSIGFVSVRQG--ALSEAAPP 367 Query: 365 GYVIALVRVSDRDSGLNGRVQCRLL---------------GNVPFRLQE-YESFSTILVD 408 G VIALVRV+DRDSG NG++QCR+L G+VPF+L+E Y++F T++ D Sbjct: 368 GTVIALVRVTDRDSGKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKLEENYDNFYTVVTD 427 Query: 409 GRLDREQHDQYNLTIQARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTP 468 LDRE D+YN+TI ARDGG P L S KSF + I DENDN P F+K Y + V ENN P Sbjct: 428 RPLDRETQDEYNVTIVARDGGSPPLNSTKSFAIKILDENDNPPRFTKGLYVLQVHENNIP 487 Query: 469 GAYLLSVSARDPDLGLNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKA 528 G YL SV A+DPDLG NG+VSY I+PS + D+ ++TYVS+NP +G IYALRSFN EQTKA Sbjct: 488 GEYLGSVLAQDPDLGQNGTVSYSILPSHIGDVSIYTYVSVNPTNGAIYALRSFNFEQTKA 547 Query: 529 FEFKVLAKDGGLPS-LQSNATVRVIILDVNDNTPVITAPPLINGTAEVYIPRNSGIGYLV 587 FEFKVLAKD G P+ L+SNATVRV +LDVNDN PVI P L N TAE+ +PRN+G+GYLV Sbjct: 548 FEFKVLAKDSGAPAHLESNATVRVTVLDVNDNAPVIVLPTLQNDTAELQVPRNAGLGYLV 607 Query: 588 TVVKAEDYDEGENGRVTYDMTEG-DRGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHD 646 + V+A D D GE+GR+TY++ +G D FEID +GE+RT F E EL+V D Sbjct: 608 STVRALDSDFGESGRLTYEIVDGNDDHLFEIDPSSGEIRTLHPFWEDVTPVVELVVKVTD 667 Query: 647 HGKTSLSASALVLIYLSPALDAQESMGSVN-------LSLIFIIALGSIAGILFVTMIFV 699 HGK +LSA A LI S + E + VN +SL I+ L +I+ IL MI + Sbjct: 668 HGKPTLSAVA-KLIIRSVSGSLPEGVPRVNGEQHHWDMSLPLIVTLSTISIILLAAMITI 726 Query: 700 AIKCKRDNKEIRTYNCRIAEYSYGH-QKKSSKKKKISKNDIRLVPRDVEETDK---MNVV 755 A+KCKR+NKEIRTYNCRIAEYS+ KKKKI+KNDI LV +VEE + MNVV Sbjct: 727 AVKCKRENKEIRTYNCRIAEYSHPQLGGGKGKKKKINKNDIMLVQSEVEERNAMNVMNVV 786 Query: 756 SCSSLTSSLNYFDYHQQTLPLGCRRSESTFLNVENQNTRNTSANHIYHHSFNSQGPQQPD 815 S SL +S YFDY Q LPL RSE +L + N + H SF QG + Sbjct: 787 SSPSLATSPMYFDY-QTRLPLSSPRSEVMYLKPASNNLTVPQGHAGCHTSFTGQGTNASE 845 Query: 816 LIINGVPLPETENYSFDSNYVNSRAHLIK-SSTFKDLEGNSLKDSGHEESDQTDSEHDVQ 874 + + +T+N+ + NY+ SR ++ SSTFKD E SL+DSGH +SDQ DS+ D Sbjct: 846 TPATRMSIIQTDNFPAEPNYMGSRQQFVQSSSTFKDPERASLRDSGHGDSDQADSDQDTN 905 Query: 875 RSLYCDTAVNDVLNTSVTSMGSQMPDHDQNEGFHCREECRILGHSDRCWMPRNPMPIRSK 934 + CD +V + L TS SQ + + E +C +ECR+LGHSDRCWMP+ P +++ Sbjct: 906 KGSCCDMSVREALKMKTTSTKSQPLEQEPEECVNCTDECRVLGHSDRCWMPQFPAANQAE 965 Query: 935 SPEHVRNIIALSIEATAADVEAYDDCGPT-KRTFATFGKDVSDHP---AEERPTLKGKRT 990 + ++ N+ ++EA + E Y+ PT K+TF TFGKD +H A +P LK KR Sbjct: 966 NADYRTNLFVPTVEAN-VETETYETVNPTGKKTFCTFGKDKREHTILIANVKPYLKAKRA 1024 Query: 991 VDVTICSPKVNSVIREAGNGCEA-ISPVTSPLHLKSSLPTKP 1031 + SP + V + + +A I P TS KP Sbjct: 1025 L-----SPLLQEVPSASSSPTKACIEPCTSTKGSLDGCEAKP 1061 >gi|14589916 protocadherin 10 isoform 1 precursor [Homo sapiens] Length = 1040 Score = 724 bits (1869), Expect = 0.0 Identities = 432/1053 (41%), Positives = 621/1053 (58%), Gaps = 102/1053 (9%) Query: 8 VLLLLAILWTQAAALINLKYSVEEEQRAGTVIANVAKDAREAGFALDPRQASAFRVVSNS 67 VLLL A+LW L Y+V+EEQ GT + N+A+D G + A F+ V NS Sbjct: 3 VLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDL---GLDITKLSARGFQTVPNS 59 Query: 68 APHLVDINPSSGLLVTKQKIDRDLLCRQSPKCIISLEV-MSSSMEICVIKVEIKDLNDNA 126 +D+N +G+L +KIDR+ +C+QSP C++ LEV + + +E+ +++E+ D+NDN Sbjct: 60 RTPYLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNP 119 Query: 127 PSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKTRGDGSR 186 PSFP + +EISE+A+PGTR PL+SA+DPD G+ ++ YE+TPN F L+++T+GDG+R Sbjct: 120 PSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNR 179 Query: 187 FAELVVEKSLDRETQSHYSFRITALDGGD----------------PP---RLGTVGLSIK 227 FAELV+EK LDRE Q+ + + +TA+DGG PP R GT L+I+ Sbjct: 180 FAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIR 239 Query: 228 VTDSNDNNPVFSESTYAVSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRE 287 V DSNDN P F + Y VS+PENSPP T VI+LNA+DPDEG NG+VVYSF +++ R RE Sbjct: 240 VLDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARE 299 Query: 288 LFQIDPHSGLVTVTGALDYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVIN 347 LF + P +G + V+G LDYEE VY++ VQAKDLGPN++PAHCKV V VLD NDN P I+ Sbjct: 300 LFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEIS 359 Query: 348 LLSVNSELVEVSESAPPGYVIALVRVSDRDSGLNGRVQCRLLGNVPFRLQ-EYESFSTIL 406 +V VSE A PG V+AL V+DRDS NG+VQC LLG+VPFRL+ ++++ TI+ Sbjct: 360 FSTVKE---AVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIV 416 Query: 407 VDGRLDREQHDQYNLTIQARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENN 466 + LDRE D Y LT+ ARD G P L ++KS V ++D NDN P FS+P Y V V ENN Sbjct: 417 TEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENN 476 Query: 467 TPGAYLLSVSARDPDLGLNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQT 526 PGAY+ +VSA D D G N ++Y I+ Q++ M VFTYVSIN +G +YALRSF++EQ Sbjct: 477 VPGAYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQL 536 Query: 527 KAFEFKVLAKDGGLP-SLQSNATVRVIILDVNDNTPVITAP-PLINGT-AEVYIPRNSGI 583 K F F+V A+D G P +L NATV ++I+D NDN P I AP P NGT A +PR++ Sbjct: 537 KDFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEP 596 Query: 584 GYLVTVVKAEDYDEGENGRVTYDMTEG-DRGFFEIDQVNGEVRTTRTF--GESSKSSYEL 640 GYL+T V A D D+GEN R+TY + G + F +D GE+RT R + YEL Sbjct: 597 GYLLTRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYEL 656 Query: 641 IVVAHDHGKTSLSASALVLIYL-SPALDAQESMG--------------------SVNLSL 679 ++ DHG+ LS++A +++ L A++ Q G S++L+L Sbjct: 657 VIEVRDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTL 716 Query: 680 IFIIALGSIAGILFVTMIFVAIKCKRDNKEIRTYNCRIAEYSY-------------GHQK 726 I IIALGS++ I + MI +A++C+++ K++ Y C ++ G Q Sbjct: 717 ILIIALGSVSFIFLLAMIVLAVRCQKE-KKLNIYTCLASDCCLCCCCCGGGGSTCCGRQA 775 Query: 727 KSSKKKKISKNDIRL-----VPRDVEETDKMNVVSCSSLTSSLNYFDYHQQTLPLGCRRS 781 + ++KKK+SK+DI L VP + + S + NY +Q L ++ Sbjct: 776 R-ARKKKLSKSDIMLVQSSNVPSNPAQVPIEESGGFGSHHHNQNY--CYQVCLTPESAKT 832 Query: 782 ESTFLNVENQNTRNTSANHIYHHSFNSQGPQQPDLIINGVPLP-ETENYSFDSNYVNSRA 840 + FL + + + ++ QQPD+I NG L ET++ + +Y+ R Sbjct: 833 DLMFLKPCSPSRSTDTEHNPCGAIVTGYTDQQPDIISNGSILSNETKHQRAELSYLVDRP 892 Query: 841 HLIKSSTFKDLEGNSLKDSGHEESDQTDSEHDVQRSLYCDTAVNDVLNTSVTSMGSQMPD 900 + SS F++ + S KDSGH +S+Q DS+HD +A D+ + Sbjct: 893 RRVNSSAFQEADIVSSKDSGHGDSEQGDSDHDATNR--AQSAGMDLFS------------ 938 Query: 901 HDQNEGFHCREECRILGHSDRCWMPRNPMPIRSKSPEHVRNIIALSIEATAADVEAYD-- 958 +C EEC+ LGHSDRCWMP + +P + R+ + + + D E ++ Sbjct: 939 -------NCTEECKALGHSDRCWMP-SFVPSDGRQAADYRSNLHVPGMDSVPDTEVFETP 990 Query: 959 DCGP-TKRTFATFGKDVSDHPAEERPTLKGKRT 990 + P +R+F+TFGK+ + H ER L G T Sbjct: 991 EAQPGAERSFSTFGKEKALHSTLERKELDGLLT 1023 >gi|14589914 protocadherin 10 isoform 2 precursor [Homo sapiens] Length = 896 Score = 657 bits (1695), Expect = 0.0 Identities = 379/879 (43%), Positives = 536/879 (60%), Gaps = 76/879 (8%) Query: 8 VLLLLAILWTQAAALINLKYSVEEEQRAGTVIANVAKDAREAGFALDPRQASAFRVVSNS 67 VLLL A+LW L Y+V+EEQ GT + N+A+D G + A F+ V NS Sbjct: 3 VLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDL---GLDITKLSARGFQTVPNS 59 Query: 68 APHLVDINPSSGLLVTKQKIDRDLLCRQSPKCIISLEV-MSSSMEICVIKVEIKDLNDNA 126 +D+N +G+L +KIDR+ +C+QSP C++ LEV + + +E+ +++E+ D+NDN Sbjct: 60 RTPYLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNP 119 Query: 127 PSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKTRGDGSR 186 PSFP + +EISE+A+PGTR PL+SA+DPD G+ ++ YE+TPN F L+++T+GDG+R Sbjct: 120 PSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNR 179 Query: 187 FAELVVEKSLDRETQSHYSFRITALDGGD----------------PP---RLGTVGLSIK 227 FAELV+EK LDRE Q+ + + +TA+DGG PP R GT L+I+ Sbjct: 180 FAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIR 239 Query: 228 VTDSNDNNPVFSESTYAVSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRE 287 V DSNDN P F + Y VS+PENSPP T VI+LNA+DPDEG NG+VVYSF +++ R RE Sbjct: 240 VLDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARE 299 Query: 288 LFQIDPHSGLVTVTGALDYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVIN 347 LF + P +G + V+G LDYEE VY++ VQAKDLGPN++PAHCKV V VLD NDN P I+ Sbjct: 300 LFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEIS 359 Query: 348 LLSVNSELVEVSESAPPGYVIALVRVSDRDSGLNGRVQCRLLGNVPFRLQ-EYESFSTIL 406 +V VSE A PG V+AL V+DRDS NG+VQC LLG+VPFRL+ ++++ TI+ Sbjct: 360 FSTVKE---AVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIV 416 Query: 407 VDGRLDREQHDQYNLTIQARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENN 466 + LDRE D Y LT+ ARD G P L ++KS V ++D NDN P FS+P Y V V ENN Sbjct: 417 TEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENN 476 Query: 467 TPGAYLLSVSARDPDLGLNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQT 526 PGAY+ +VSA D D G N ++Y I+ Q++ M VFTYVSIN +G +YALRSF++EQ Sbjct: 477 VPGAYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQL 536 Query: 527 KAFEFKVLAKDGGLP-SLQSNATVRVIILDVNDNTPVITAP-PLINGT-AEVYIPRNSGI 583 K F F+V A+D G P +L NATV ++I+D NDN P I AP P NGT A +PR++ Sbjct: 537 KDFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEP 596 Query: 584 GYLVTVVKAEDYDEGENGRVTYDMTEG-DRGFFEIDQVNGEVRTTRTF--GESSKSSYEL 640 GYL+T V A D D+GEN R+TY + G + F +D GE+RT R + YEL Sbjct: 597 GYLLTRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYEL 656 Query: 641 IVVAHDHGKTSLSASALVLIYL-SPALDAQESMG--------------------SVNLSL 679 ++ DHG+ LS++A +++ L A++ Q G S++L+L Sbjct: 657 VIEVRDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTL 716 Query: 680 IFIIALGSIAGILFVTMIFVAIKCKRDNKEIRTYNCRIAEYSY-------------GHQK 726 I IIALGS++ I + MI +A++C+++ K++ Y C ++ G Q Sbjct: 717 ILIIALGSVSFIFLLAMIVLAVRCQKE-KKLNIYTCLASDCCLCCCCCGGGGSTCCGRQA 775 Query: 727 KSSKKKKISKNDIRL-----VPRDVEETDKMNVVSCSSLTSSLNYFDYHQQTLPLGCRRS 781 + ++KKK+SK+DI L VP + + S + NY +Q L ++ Sbjct: 776 R-ARKKKLSKSDIMLVQSSNVPSNPAQVPIEESGGFGSHHHNQNY--CYQVCLTPESAKT 832 Query: 782 ESTFLNVENQNTRNTSANHIYHHSFNSQGPQQPDLIING 820 + FL + + + ++ QQPD+I NG Sbjct: 833 DLMFLKPCSPSRSTDTEHNPCGAIVTGYTDQQPDIISNG 871 >gi|14589929 protocadherin 18 precursor [Homo sapiens] Length = 1135 Score = 635 bits (1637), Expect = 0.0 Identities = 388/1079 (35%), Positives = 597/1079 (55%), Gaps = 49/1079 (4%) Query: 8 VLLLLAILWTQAAALINLKYSVEEEQRAGTVIANVAKDAREAGFALDPRQASAFRVVSNS 67 V LL + + NLKY + EEQR G+VIA +++D + L FR + Sbjct: 13 VFALLIVSFNHDVLGKNLKYRIYEEQRVGSVIARLSEDVADVLLKLPNPSTVRFRAMQRG 72 Query: 68 APHLVDINPSSGLLVTKQKIDRDLLCRQSPKCIISLEVMS---SSMEICVIKVEIKDLND 124 L+ +N +G + IDR+ LC+++ C I +V++ +++ I+VE+ D+ND Sbjct: 73 NSPLLVVNEDNGEISIGATIDREQLCQKNLNCSIEFDVITLPTEHLQLFHIEVEVLDIND 132 Query: 125 NAPSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKTRGDG 184 N+P F + I +EISE+A+ GTRIPLDSA+DPD G + TY L+ N+ F +E++TR DG Sbjct: 133 NSPQFSRSLIPIEISESAAVGTRIPLDSAFDPDVGENSLHTYSLSANDFFNIEVRTRTDG 192 Query: 185 SRFAELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNPVFSESTYA 244 +++AEL+V + LDRE +S Y ++TA D G P R G+ L I ++DSNDN+P F + +Y Sbjct: 193 AKYAELIVVRELDRELKSSYELQLTASDMGVPQRSGSSILKISISDSNDNSPAFEQQSYI 252 Query: 245 VSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTVTGAL 304 + + ENSP T ++ LNA+DPDEG NG++VYSF +V+ + E F+ID G +T+ + Sbjct: 253 IQLLENSPVGTLLLDLNATDPDEGANGKIVYSFSSHVSPKIMETFKIDSERGHLTLFKQV 312 Query: 305 DYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVS---ES 361 DYE YE+DVQA+DLGPNSIPAHCK+ + V+D NDN P IN+ ++ E+S E Sbjct: 313 DYEITKSYEIDVQAQDLGPNSIPAHCKIIIKVVDVNDNKPEININLMSPGKEEISYIFEG 372 Query: 362 APPGYVIALVRVSDRDSGLNGRVQCRLLGNVPFRLQE-YESFSTILVDGRLDREQHDQYN 420 P +ALVRV D+DSGLNG + C+L G+ F+LQ+ YE+ IL + LDRE+ +Y+ Sbjct: 373 DPIDTFVALVRVQDKDSGLNGEIVCKLHGHGHFKLQKTYENNYLILTNATLDREKRSEYS 432 Query: 421 LTIQARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDP 480 LT+ A D G P L + K FTV I D NDN PHF + Y+ ++ ENN+PGAY+ +V+A DP Sbjct: 433 LTVIAEDRGTPSLSTVKHFTVQINDINDNPPHFQRSRYEFVISENNSPGAYITTVTATDP 492 Query: 481 DLGLNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGGL 540 DLG NG V+Y I+ S + + TYV+I+P++G IYALR F+HE+ F V A+DGG Sbjct: 493 DLGENGQVTYTILESFILGSSITTYVTIDPSNGAIYALRIFDHEEVSQITFVVEARDGGS 552 Query: 541 P-SLQSNATVRVIILDVNDNTPVITAPPLINGTAEVYIPRNSGIGYLVTVVKAEDYDEGE 599 P L SN TV + I+D NDN PV+ P L N TAE+ IP+ + G+ VT ++A D D G Sbjct: 553 PKQLVSNTTVVLTIIDENDNVPVVIGPALRNNTAEITIPKGAESGFHVTRIRAIDRDSGV 612 Query: 600 NGRVTYDMTEG-DRGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGKTSLSASALV 658 N ++ + G + F ID + ++ T + + +EL V+ D G L L+ Sbjct: 613 NAELSCAIVAGNEENIFIIDPRSCDIHTNVSMDSVPYTEWELSVIIQDKGNPQLHTKVLL 672 Query: 659 --LIY-----LSPALDAQESMGSVNLSLIFIIALGSIAGILFVTMIFVAIKCKRDNKEIR 711 +I+ ++ S S+++S+I II+LG+I +L V M+ A +C R+ K+ R Sbjct: 673 KCMIFEYAESVTSTAMTSVSQASLDVSMIIIISLGAICAVLLVIMVLFATRCNREKKDTR 732 Query: 712 TYNCRIAEYSYGHQKKSSKKKKISKNDIRLVPRDVEETDKMNVVSCSSLTSSLNYFDYHQ 771 +YNCR+AE +Y H K ++I K DI LVP + T + SS +SS Sbjct: 733 SYNCRVAESTYQHHPK-RPSRQIHKGDITLVP-TINGTLPIRSHHRSSPSSSPTL----- 785 Query: 772 QTLPLGCRRSESTFLNVENQNTRNTSANHIYHHSFNSQGPQQP--DLIINGVPLPETENY 829 + +G R+S ++ ++ + T S+NH+ + P + + + + Y Sbjct: 786 ERGQMGSRQSHNSHQSLNSLVT--ISSNHVPENFSLELTHATPAVEQVSQLLSMLHQGQY 843 Query: 830 SFDSNYVNSRAHLIKSSTFKDLEGNSLKDSGHEESDQTDSEHDVQRSLYCDTAVNDVLNT 889 ++ ++ +D++ SLKDSG +S+ DS++D+ R D + + + Sbjct: 844 QPRPSFRGNKYSRSYRYALQDMDKFSLKDSGRGDSEAGDSDYDLGRDSPIDRLLGEGFSD 903 Query: 890 SVTSMGSQMPDHDQNEGFHCREECRILGHSDRCWMPRNPMPIRSKSPEHVRNIIALSIEA 949 + G ++P + C EECR+LGHSD+CWMP P+ S S ++ N+ E Sbjct: 904 LFLTDG-RIPAAMR----LCTEECRVLGHSDQCWMP----PLPSPSSDYRSNMFIPGEEF 954 Query: 950 TAADVEAYD-----------DCGPTKRTFATFGKDVSDHPAEERPTLKGKRTVDVTICSP 998 + + D G K++F+TFGKD S + + T +++ Sbjct: 955 PTQPQQQHPHQSLEDDAQPADSGEKKKSFSTFGKD-SPNDEDTGDTSTSSLLSEMSSVFQ 1013 Query: 999 KVNSVIREAGNGCEAISPVTSPLHLKSSLPTKPSVSYTIALAPPARDLEQYVNNVNNGP 1057 ++ + + C + S K LP K +V Y +A A N GP Sbjct: 1014 RLLPPSLDTYSECSEVDRSNSLERRKGPLPAK-TVGYPQGVAAWAASTHFQNPTTNCGP 1071 >gi|9256600 protocadherin alpha subfamily C, 2 isoform 1 precursor [Homo sapiens] Length = 1007 Score = 543 bits (1400), Expect = e-154 Identities = 300/717 (41%), Positives = 443/717 (61%), Gaps = 22/717 (3%) Query: 4 LLLPVLLLLAILWTQAAALINLKYSVEEEQRAGTVIANVAKDAREAGFALDPRQASAFRV 63 LLLP+LLLL +L AA L+YSV EEQ G ++ NVA R G L R+ Sbjct: 24 LLLPLLLLLLLLLPGPAAS-QLRYSVPEEQAPGALVGNVA---RALGLELRRLGPGCLRI 79 Query: 64 --VSNSAPHLVDINPSSGLLVTKQKIDRDLLCRQSPKCIISLEVMSSS-MEICVIKVEIK 120 + +P ++++ +SG L ++IDR+ LC Q P+C++SLEV++ + + + ++VEI Sbjct: 80 NHLGAPSPRYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEIL 139 Query: 121 DLNDNAPSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKT 180 D+NDN+P FP +L++SE+ +PG R ++SA DPD G+ VQTYEL+P+E F L++K Sbjct: 140 DINDNSPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKP 199 Query: 181 RGDGSRFAELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNPVFSE 240 + S+ ELV+ K LDRE + + +TA+DGG P R GT +S++V D+NDN+P F + Sbjct: 200 LQENSKVLELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQ 259 Query: 241 STYAVSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTV 300 STY V + E+SPP T V++LNASDPDEG+NG++ YS Y +DR R+LF ID +G V V Sbjct: 260 STYRVQLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRV 319 Query: 301 TGALDYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSE 360 G LDYEE Y++ VQA D GP + HCKV V ++D NDN P + L + S V E Sbjct: 320 IGGLDYEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYS---PVPE 376 Query: 361 SAPPGYVIALVRVSDRDSGLNGRVQCRLLGNVPFRLQEYESFSTILVDGRLDREQHDQYN 420 +A P ++A++ V+D+DSG N +V L +PFRL + + T++V G LDRE+ YN Sbjct: 377 NATPNTIVAVLSVNDQDSGPNRKVSLGLEATLPFRLNGFGNSYTLVVSGPLDRERVAVYN 436 Query: 421 LTIQARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDP 480 +T+ A DGG+P L S ++ V I+D NDN P F + Y + +QENN PG L +V A DP Sbjct: 437 ITVTATDGGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDP 496 Query: 481 DLGLNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGGL 540 D N V+Y ++ +++ +PV +YVSIN SG +YA+ SF++E+ + F V A+D G Sbjct: 497 DEKENAEVTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGS 556 Query: 541 PSLQSNATVRVIILDVNDNTPVITAPPLINGTAEV-YIPRNSGIGYLVTVVKAEDYDEGE 599 P L S T V ++D+ND+ P I P N +A +PR + GYLVT V A D D G+ Sbjct: 557 PPLSSTVTANVYVVDMNDHAPHILYPTSTNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQ 616 Query: 600 NGRVTYDMTE-GDRGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGKTSLSASALV 658 N + Y + + D F+++ GE+RTTR G+ S S++ L VV D+G+ SLSAS + Sbjct: 617 NAWLFYHLAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAI 676 Query: 659 LIYLSPAL-----DAQESMGS----VNLSLIFIIALGSIAGILFVTMIFVA-IKCKR 705 + + + D Q + S ++L IIAL +++ I +T+I ++ IKC R Sbjct: 677 TVAVVDRVSKILPDTQRHVKSPRTYSEITLYLIIALSTVSFIFLLTIIILSIIKCYR 733 >gi|14165431 protocadherin alpha subfamily C, 2 isoform 2 precursor [Homo sapiens] Length = 884 Score = 543 bits (1400), Expect = e-154 Identities = 300/717 (41%), Positives = 443/717 (61%), Gaps = 22/717 (3%) Query: 4 LLLPVLLLLAILWTQAAALINLKYSVEEEQRAGTVIANVAKDAREAGFALDPRQASAFRV 63 LLLP+LLLL +L AA L+YSV EEQ G ++ NVA R G L R+ Sbjct: 24 LLLPLLLLLLLLLPGPAAS-QLRYSVPEEQAPGALVGNVA---RALGLELRRLGPGCLRI 79 Query: 64 --VSNSAPHLVDINPSSGLLVTKQKIDRDLLCRQSPKCIISLEVMSSS-MEICVIKVEIK 120 + +P ++++ +SG L ++IDR+ LC Q P+C++SLEV++ + + + ++VEI Sbjct: 80 NHLGAPSPRYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEIL 139 Query: 121 DLNDNAPSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKT 180 D+NDN+P FP +L++SE+ +PG R ++SA DPD G+ VQTYEL+P+E F L++K Sbjct: 140 DINDNSPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKP 199 Query: 181 RGDGSRFAELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNPVFSE 240 + S+ ELV+ K LDRE + + +TA+DGG P R GT +S++V D+NDN+P F + Sbjct: 200 LQENSKVLELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQ 259 Query: 241 STYAVSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTV 300 STY V + E+SPP T V++LNASDPDEG+NG++ YS Y +DR R+LF ID +G V V Sbjct: 260 STYRVQLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRV 319 Query: 301 TGALDYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSE 360 G LDYEE Y++ VQA D GP + HCKV V ++D NDN P + L + S V E Sbjct: 320 IGGLDYEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYS---PVPE 376 Query: 361 SAPPGYVIALVRVSDRDSGLNGRVQCRLLGNVPFRLQEYESFSTILVDGRLDREQHDQYN 420 +A P ++A++ V+D+DSG N +V L +PFRL + + T++V G LDRE+ YN Sbjct: 377 NATPNTIVAVLSVNDQDSGPNRKVSLGLEATLPFRLNGFGNSYTLVVSGPLDRERVAVYN 436 Query: 421 LTIQARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDP 480 +T+ A DGG+P L S ++ V I+D NDN P F + Y + +QENN PG L +V A DP Sbjct: 437 ITVTATDGGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDP 496 Query: 481 DLGLNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGGL 540 D N V+Y ++ +++ +PV +YVSIN SG +YA+ SF++E+ + F V A+D G Sbjct: 497 DEKENAEVTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGS 556 Query: 541 PSLQSNATVRVIILDVNDNTPVITAPPLINGTAEV-YIPRNSGIGYLVTVVKAEDYDEGE 599 P L S T V ++D+ND+ P I P N +A +PR + GYLVT V A D D G+ Sbjct: 557 PPLSSTVTANVYVVDMNDHAPHILYPTSTNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQ 616 Query: 600 NGRVTYDMTE-GDRGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGKTSLSASALV 658 N + Y + + D F+++ GE+RTTR G+ S S++ L VV D+G+ SLSAS + Sbjct: 617 NAWLFYHLAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAI 676 Query: 659 LIYLSPAL-----DAQESMGS----VNLSLIFIIALGSIAGILFVTMIFVA-IKCKR 705 + + + D Q + S ++L IIAL +++ I +T+I ++ IKC R Sbjct: 677 TVAVVDRVSKILPDTQRHVKSPRTYSEITLYLIIALSTVSFIFLLTIIILSIIKCYR 733 >gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens] Length = 936 Score = 494 bits (1273), Expect = e-139 Identities = 281/748 (37%), Positives = 429/748 (57%), Gaps = 34/748 (4%) Query: 8 VLLLLAILWTQAAALINLKYSVEEEQRAGTVIANVAKDAREAGFALDPRQASAFRVVSNS 67 +LLL +L A L YS+ EE + GT + +A+D L PR FRV S Sbjct: 13 LLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPR---LFRVASKG 69 Query: 68 APHLVDINPSSGLLVTKQKIDRDLLCRQSPKCIISLEVM-SSSMEICVIKVEIKDLNDNA 126 L+++N +G+L +IDR+ LCR+ +C I LEV+ +++ ++V +KD+NDN Sbjct: 70 RGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVAVKDINDNP 129 Query: 127 PSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKTRGDGSR 186 P F + L I E+ P +R PL+ A D D G+ Y L PNE F L++KT + + Sbjct: 130 PRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDVKTNEEETN 189 Query: 187 FAELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNPVFSESTYAVS 246 F ELV+ KSLDRE + + A DGG P GTV L I V D+NDN P F +S Y V Sbjct: 190 FLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEFDKSIYNVR 249 Query: 247 VPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTVTGALDY 306 + EN+P T VI+LNASD DEG N ++VY F V D + F I+ ++G + V G LDY Sbjct: 250 LLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEIKVNGELDY 309 Query: 307 EEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSESAPPGY 366 E+ + YE+++ A D + HCKV V +LD NDN P +++ + + V E AP Sbjct: 310 EDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPE---MAITTLFLPVKEDAPLST 366 Query: 367 VIALVRVSDRDSGLNGRVQCRLLGNVPFRL-QEYESFSTILVDGRLDREQHDQYNLTIQA 425 VIAL+ VSDRDSG NG+V C L+ +VPF+L ++++ ++++D LDRE Y L + A Sbjct: 367 VIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYELVVTA 426 Query: 426 RDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDPDLGLN 485 RDGG P L + S +V + D NDN P F++P Y V V+ENN PG ++ +VSARD D N Sbjct: 427 RDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDADAQEN 486 Query: 486 GSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGGLPSLQS 545 VSY +V +V + P+ +YVS++ SG +YAL+ +HE+ + +F+V A+D G+P L S Sbjct: 487 ALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGS 546 Query: 546 NATVRVIILDVNDNTPVITAPPL--INGTAEVYIPRNSGIGYLVTVVKAEDYDEGENGRV 603 N T++V +LD NDN P + P + G +PR+ G G++V V+A D D G N + Sbjct: 547 NVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSGYNAWL 606 Query: 604 TYDMTEGD---RGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGKTSLSASALVLI 660 +Y++ R F + GE+ TTR+ E+ + L+V+ DHG+ L+A+A VL+ Sbjct: 607 SYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTATATVLV 666 Query: 661 YL-----SPALDAQESMGS-------VNLSLIFIIALGSIAGILFVT-MIFVAIKCKRD- 706 L +P ++ S G+ V++++ IIA+ +++ +L +T +++ A++C Sbjct: 667 SLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAQP 726 Query: 707 -------NKEIRTYNCRIAEYSYGHQKK 727 K + + +SY Q++ Sbjct: 727 TEAVCTRGKPTLLCSSAVGSWSYSQQRR 754 >gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo sapiens] Length = 816 Score = 494 bits (1273), Expect = e-139 Identities = 281/748 (37%), Positives = 429/748 (57%), Gaps = 34/748 (4%) Query: 8 VLLLLAILWTQAAALINLKYSVEEEQRAGTVIANVAKDAREAGFALDPRQASAFRVVSNS 67 +LLL +L A L YS+ EE + GT + +A+D L PR FRV S Sbjct: 13 LLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPR---LFRVASKG 69 Query: 68 APHLVDINPSSGLLVTKQKIDRDLLCRQSPKCIISLEVM-SSSMEICVIKVEIKDLNDNA 126 L+++N +G+L +IDR+ LCR+ +C I LEV+ +++ ++V +KD+NDN Sbjct: 70 RGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVAVKDINDNP 129 Query: 127 PSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKTRGDGSR 186 P F + L I E+ P +R PL+ A D D G+ Y L PNE F L++KT + + Sbjct: 130 PRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDVKTNEEETN 189 Query: 187 FAELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNPVFSESTYAVS 246 F ELV+ KSLDRE + + A DGG P GTV L I V D+NDN P F +S Y V Sbjct: 190 FLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEFDKSIYNVR 249 Query: 247 VPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTVTGALDY 306 + EN+P T VI+LNASD DEG N ++VY F V D + F I+ ++G + V G LDY Sbjct: 250 LLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEIKVNGELDY 309 Query: 307 EEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSESAPPGY 366 E+ + YE+++ A D + HCKV V +LD NDN P +++ + + V E AP Sbjct: 310 EDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPE---MAITTLFLPVKEDAPLST 366 Query: 367 VIALVRVSDRDSGLNGRVQCRLLGNVPFRL-QEYESFSTILVDGRLDREQHDQYNLTIQA 425 VIAL+ VSDRDSG NG+V C L+ +VPF+L ++++ ++++D LDRE Y L + A Sbjct: 367 VIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYELVVTA 426 Query: 426 RDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDPDLGLN 485 RDGG P L + S +V + D NDN P F++P Y V V+ENN PG ++ +VSARD D N Sbjct: 427 RDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDADAQEN 486 Query: 486 GSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGGLPSLQS 545 VSY +V +V + P+ +YVS++ SG +YAL+ +HE+ + +F+V A+D G+P L S Sbjct: 487 ALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGS 546 Query: 546 NATVRVIILDVNDNTPVITAPPL--INGTAEVYIPRNSGIGYLVTVVKAEDYDEGENGRV 603 N T++V +LD NDN P + P + G +PR+ G G++V V+A D D G N + Sbjct: 547 NVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSGYNAWL 606 Query: 604 TYDMTEGD---RGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGKTSLSASALVLI 660 +Y++ R F + GE+ TTR+ E+ + L+V+ DHG+ L+A+A VL+ Sbjct: 607 SYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTATATVLV 666 Query: 661 YL-----SPALDAQESMGS-------VNLSLIFIIALGSIAGILFVT-MIFVAIKCKRD- 706 L +P ++ S G+ V++++ IIA+ +++ +L +T +++ A++C Sbjct: 667 SLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAQP 726 Query: 707 -------NKEIRTYNCRIAEYSYGHQKK 727 K + + +SY Q++ Sbjct: 727 TEAVCTRGKPTLLCSSAVGSWSYSQQRR 754 >gi|14196468 protocadherin gamma subfamily A, 4 isoform 2 precursor [Homo sapiens] Length = 820 Score = 492 bits (1267), Expect = e-139 Identities = 288/723 (39%), Positives = 427/723 (59%), Gaps = 33/723 (4%) Query: 5 LLPVLLLLAILWTQAAALINLKYSVEEEQRAGTVIANVAKDAREAGFALDPRQAS--AFR 62 LL + LLL +L A I YSV EEQ G+V+ N+AKD L PR+ + R Sbjct: 13 LLQICLLLGVLVEIRAEQI--LYSVFEEQEEGSVVGNIAKD-----LGLAPRELAERGVR 65 Query: 63 VVSNSAPHLVDINPSSGLLVTKQKIDRDLLCRQSPKCIISLEVM-SSSMEICVIKVEIKD 121 +VS L +NP SG LVT +IDR+ LC +SP C+ +LE++ +++I ++VEI D Sbjct: 66 IVSRGRTQLFALNPRSGTLVTAGRIDREELCDRSPNCVTNLEILLEDTVKILRVEVEIID 125 Query: 122 LNDNAPSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKTR 181 +NDN PSF Q E++++E +PG R PL A+DPD G +Q Y+L N F L++++ Sbjct: 126 VNDNPPSFGTEQREIKVAENENPGARFPLPEAFDPDVGVNSLQGYQLNSNGYFSLDVQSG 185 Query: 182 GDGSRFAELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNPVFSES 241 DG ++ ELV+E++LDRE ++ + +TA DGGDP R GT + I + D+NDN PVF++ Sbjct: 186 ADGIKYPELVLERALDREEEAVHHLVLTAFDGGDPVRSGTARILIILVDTNDNAPVFTQP 245 Query: 242 TYAVSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTVT 301 Y VSV EN P T ++ + A+DPDEG NG V YSF V D+ +LFQ++ SG +T+ Sbjct: 246 EYHVSVRENVPVGTRLLTVKATDPDEGANGDVTYSF-RKVRDKISQLFQLNSLSGDITIL 304 Query: 302 GALDYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSES 361 G LDYE+ Y++DV+A D GP + A KV V+VLD NDN P + + S+ S V ES Sbjct: 305 GGLDYEDSGFYDIDVEAHD-GP-GLRARSKVLVTVLDENDNAPEVTVTSLTS---SVQES 359 Query: 362 APPGYVIALVRVSDRDSGLNGRVQCRLLGNVPFRLQE-YESFSTILVDGRLDREQHDQYN 420 + PG VIAL V D DSG NG V C + N+PF L++ Y ++ +L LDRE+ +YN Sbjct: 360 SSPGTVIALFNVHDSDSGGNGLVTCSIPDNLPFTLEKTYGNYYRLLTHRTLDREEVSEYN 419 Query: 421 LTIQARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDP 480 +T+ A D G P L + ++ + D NDN P F Y + ENN GA +LS++A+DP Sbjct: 420 ITVTATDQGTPPLSTETHISLQVMDINDNPPTFPHASYSAYIPENNPRGASILSMTAQDP 479 Query: 481 DLGLNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGGL 540 D G N ++Y + + P+ +YVSIN N+G +YAL SF++EQ + + + A D G Sbjct: 480 DSGDNARITYSLAEDTFQGAPLSSYVSINSNTGILYALCSFDYEQFRDLQLLMTASDSGD 539 Query: 541 PSLQSNATVRVIILDVNDNTPVITAP--PLINGTAEVYIPRNSGIGYLVTVVKAEDYDEG 598 P L SN ++ + +LD NDN P I P P T PR++ GYLVT V A D D G Sbjct: 540 PPLSSNVSLSLFVLDQNDNVPEILYPTFPTDGSTGVELAPRSADSGYLVTKVVAVDRDSG 599 Query: 599 ENGRVTYDMTE-GDRGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGKTSLSASAL 657 +N ++Y + + + G F + GEVRT R + L+VV DHG+ LSA+ Sbjct: 600 QNAWLSYSLLKSSEPGLFAVGLHTGEVRTARALLDRDALKQRLVVVVQDHGQPPLSATVT 659 Query: 658 VLIYLSPAL-DAQESMGSV---------NLSLIFIIALGSIAGIL--FVTMIFVAIKCKR 705 + + ++ ++ D +GS+ L+L ++A+ +++ + FVT + +A+K +R Sbjct: 660 LTVAVADSIPDVLADLGSLKPSADPDDSGLTLYLVVAVAAVSCVFLAFVT-VLLALKLRR 718 Query: 706 DNK 708 +K Sbjct: 719 WHK 721 >gi|11056026 protocadherin gamma subfamily A, 4 isoform 1 precursor [Homo sapiens] Length = 931 Score = 492 bits (1267), Expect = e-139 Identities = 288/723 (39%), Positives = 427/723 (59%), Gaps = 33/723 (4%) Query: 5 LLPVLLLLAILWTQAAALINLKYSVEEEQRAGTVIANVAKDAREAGFALDPRQAS--AFR 62 LL + LLL +L A I YSV EEQ G+V+ N+AKD L PR+ + R Sbjct: 13 LLQICLLLGVLVEIRAEQI--LYSVFEEQEEGSVVGNIAKD-----LGLAPRELAERGVR 65 Query: 63 VVSNSAPHLVDINPSSGLLVTKQKIDRDLLCRQSPKCIISLEVM-SSSMEICVIKVEIKD 121 +VS L +NP SG LVT +IDR+ LC +SP C+ +LE++ +++I ++VEI D Sbjct: 66 IVSRGRTQLFALNPRSGTLVTAGRIDREELCDRSPNCVTNLEILLEDTVKILRVEVEIID 125 Query: 122 LNDNAPSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKTR 181 +NDN PSF Q E++++E +PG R PL A+DPD G +Q Y+L N F L++++ Sbjct: 126 VNDNPPSFGTEQREIKVAENENPGARFPLPEAFDPDVGVNSLQGYQLNSNGYFSLDVQSG 185 Query: 182 GDGSRFAELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNPVFSES 241 DG ++ ELV+E++LDRE ++ + +TA DGGDP R GT + I + D+NDN PVF++ Sbjct: 186 ADGIKYPELVLERALDREEEAVHHLVLTAFDGGDPVRSGTARILIILVDTNDNAPVFTQP 245 Query: 242 TYAVSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTVT 301 Y VSV EN P T ++ + A+DPDEG NG V YSF V D+ +LFQ++ SG +T+ Sbjct: 246 EYHVSVRENVPVGTRLLTVKATDPDEGANGDVTYSF-RKVRDKISQLFQLNSLSGDITIL 304 Query: 302 GALDYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSES 361 G LDYE+ Y++DV+A D GP + A KV V+VLD NDN P + + S+ S V ES Sbjct: 305 GGLDYEDSGFYDIDVEAHD-GP-GLRARSKVLVTVLDENDNAPEVTVTSLTS---SVQES 359 Query: 362 APPGYVIALVRVSDRDSGLNGRVQCRLLGNVPFRLQE-YESFSTILVDGRLDREQHDQYN 420 + PG VIAL V D DSG NG V C + N+PF L++ Y ++ +L LDRE+ +YN Sbjct: 360 SSPGTVIALFNVHDSDSGGNGLVTCSIPDNLPFTLEKTYGNYYRLLTHRTLDREEVSEYN 419 Query: 421 LTIQARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDP 480 +T+ A D G P L + ++ + D NDN P F Y + ENN GA +LS++A+DP Sbjct: 420 ITVTATDQGTPPLSTETHISLQVMDINDNPPTFPHASYSAYIPENNPRGASILSMTAQDP 479 Query: 481 DLGLNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGGL 540 D G N ++Y + + P+ +YVSIN N+G +YAL SF++EQ + + + A D G Sbjct: 480 DSGDNARITYSLAEDTFQGAPLSSYVSINSNTGILYALCSFDYEQFRDLQLLMTASDSGD 539 Query: 541 PSLQSNATVRVIILDVNDNTPVITAP--PLINGTAEVYIPRNSGIGYLVTVVKAEDYDEG 598 P L SN ++ + +LD NDN P I P P T PR++ GYLVT V A D D G Sbjct: 540 PPLSSNVSLSLFVLDQNDNVPEILYPTFPTDGSTGVELAPRSADSGYLVTKVVAVDRDSG 599 Query: 599 ENGRVTYDMTE-GDRGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGKTSLSASAL 657 +N ++Y + + + G F + GEVRT R + L+VV DHG+ LSA+ Sbjct: 600 QNAWLSYSLLKSSEPGLFAVGLHTGEVRTARALLDRDALKQRLVVVVQDHGQPPLSATVT 659 Query: 658 VLIYLSPAL-DAQESMGSV---------NLSLIFIIALGSIAGIL--FVTMIFVAIKCKR 705 + + ++ ++ D +GS+ L+L ++A+ +++ + FVT + +A+K +R Sbjct: 660 LTVAVADSIPDVLADLGSLKPSADPDDSGLTLYLVVAVAAVSCVFLAFVT-VLLALKLRR 718 Query: 706 DNK 708 +K Sbjct: 719 WHK 721 >gi|14277682 protocadherin gamma subfamily C, 4 isoform 2 precursor [Homo sapiens] Length = 871 Score = 492 bits (1266), Expect = e-139 Identities = 285/698 (40%), Positives = 410/698 (58%), Gaps = 28/698 (4%) Query: 25 LKYSVEEEQRAGTVIANVAKDAREAGFALDPRQASAFRVVS----NSAPHLVDINPSSGL 80 ++Y V EE + GT + NVA+D F LD SA R+ N VD++ SG Sbjct: 31 IRYPVPEESQEGTFVGNVAQD-----FLLDTDSLSARRLQVAGEVNQRHFRVDLD--SGA 83 Query: 81 LVTKQKIDRDLLCRQSPKCIISLE-VMSSSMEICVIKVEIKDLNDNAPSFPAAQIELEIS 139 L+ K IDR+ LC S CI+ LE V +E+ +VEI D+ND+AP FP Q++LEI Sbjct: 84 LLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQQLDLEIG 143 Query: 140 EAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKTRGDGSRFAELVVEKSLDRE 199 EAA PG R PL+ A D D GS + +Y L+ NE F L++K R DGS EL++EK LDRE Sbjct: 144 EAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLLEKPLDRE 203 Query: 200 TQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNPVFSESTYAVSVPENSPPNTPVIR 259 QS Y +TA+DGG+PPR GT L + V D NDN P F +S+Y +SV E++P +I+ Sbjct: 204 KQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAPAGMVLIQ 263 Query: 260 LNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTVTGALDYEEGHVYELDVQAK 319 LNASDPD G +G V + F G+ DR R LF + P +G +T+ G LD+E + YE DV+A+ Sbjct: 264 LNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESENYYEFDVRAR 323 Query: 320 DLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSESAPPGYVIALVRVSDRDSG 379 D G ++ HC + V +LD NDN P I +V SEL + ESA PG V+AL+ V D DSG Sbjct: 324 DGGSPAMEQHCSLRVDLLDVNDNAPYI---TVTSELGTLPESAEPGTVVALISVQDPDSG 380 Query: 380 LNGRVQCRLLGNVPFRLQE-YESFSTILVDGRLDREQHDQYNLTIQARDGGVPMLQSAKS 438 NG V R+ ++PF L+ + + +++ G LDRE Y++ + A D G P L + ++ Sbjct: 381 SNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLSTHRT 440 Query: 439 FTVLITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDPDLGLNGSVSYQIVPSQVR 498 + I+D NDN P F + ++V V ENN PG L S++A DPD GLN +SY ++ + R Sbjct: 441 IFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSLLEPRNR 500 Query: 499 DMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGGLPSLQSNATVRVIILDVND 558 D+ +++S+NP +G ++A RSF++EQT+ +F+V A+D G P L S TVR+ +LD+ND Sbjct: 501 DVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLFVLDLND 560 Query: 559 NTPVITAPPLINGT-AEVYIPRNSGIGYLVTVVKAEDYDEGENGRVTYDMTEG-DRGFFE 616 N P + P G+ +P + G G+L+T V A D D G N V+Y + E D F Sbjct: 561 NAPAVLRPRARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLLEAPDPSLFA 620 Query: 617 IDQVNGEVRTTRTFGESSKSSYELIVVAHDHGKTSLSASALVLIYLS----PAL-DAQES 671 + + GEVRT + +L++V D G LS S +L+ L P + D +ES Sbjct: 621 VSRYAGEVRTAVPI-PADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPVVPDLRES 679 Query: 672 M----GSVNLSLIFIIALGSIAGILFVTMIFVAIKCKR 705 G L+L ++L +I + F + + + KC R Sbjct: 680 SAPREGESRLTLYLAVSLVAICFVSFGSFVALLSKCLR 717 >gi|11128025 protocadherin gamma subfamily C, 4 isoform 1 precursor [Homo sapiens] Length = 938 Score = 492 bits (1266), Expect = e-139 Identities = 285/698 (40%), Positives = 410/698 (58%), Gaps = 28/698 (4%) Query: 25 LKYSVEEEQRAGTVIANVAKDAREAGFALDPRQASAFRVVS----NSAPHLVDINPSSGL 80 ++Y V EE + GT + NVA+D F LD SA R+ N VD++ SG Sbjct: 31 IRYPVPEESQEGTFVGNVAQD-----FLLDTDSLSARRLQVAGEVNQRHFRVDLD--SGA 83 Query: 81 LVTKQKIDRDLLCRQSPKCIISLE-VMSSSMEICVIKVEIKDLNDNAPSFPAAQIELEIS 139 L+ K IDR+ LC S CI+ LE V +E+ +VEI D+ND+AP FP Q++LEI Sbjct: 84 LLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQQLDLEIG 143 Query: 140 EAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKTRGDGSRFAELVVEKSLDRE 199 EAA PG R PL+ A D D GS + +Y L+ NE F L++K R DGS EL++EK LDRE Sbjct: 144 EAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLLEKPLDRE 203 Query: 200 TQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNPVFSESTYAVSVPENSPPNTPVIR 259 QS Y +TA+DGG+PPR GT L + V D NDN P F +S+Y +SV E++P +I+ Sbjct: 204 KQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAPAGMVLIQ 263 Query: 260 LNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTVTGALDYEEGHVYELDVQAK 319 LNASDPD G +G V + F G+ DR R LF + P +G +T+ G LD+E + YE DV+A+ Sbjct: 264 LNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESENYYEFDVRAR 323 Query: 320 DLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSESAPPGYVIALVRVSDRDSG 379 D G ++ HC + V +LD NDN P I +V SEL + ESA PG V+AL+ V D DSG Sbjct: 324 DGGSPAMEQHCSLRVDLLDVNDNAPYI---TVTSELGTLPESAEPGTVVALISVQDPDSG 380 Query: 380 LNGRVQCRLLGNVPFRLQE-YESFSTILVDGRLDREQHDQYNLTIQARDGGVPMLQSAKS 438 NG V R+ ++PF L+ + + +++ G LDRE Y++ + A D G P L + ++ Sbjct: 381 SNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLSTHRT 440 Query: 439 FTVLITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDPDLGLNGSVSYQIVPSQVR 498 + I+D NDN P F + ++V V ENN PG L S++A DPD GLN +SY ++ + R Sbjct: 441 IFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSLLEPRNR 500 Query: 499 DMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGGLPSLQSNATVRVIILDVND 558 D+ +++S+NP +G ++A RSF++EQT+ +F+V A+D G P L S TVR+ +LD+ND Sbjct: 501 DVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLFVLDLND 560 Query: 559 NTPVITAPPLINGT-AEVYIPRNSGIGYLVTVVKAEDYDEGENGRVTYDMTEG-DRGFFE 616 N P + P G+ +P + G G+L+T V A D D G N V+Y + E D F Sbjct: 561 NAPAVLRPRARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLLEAPDPSLFA 620 Query: 617 IDQVNGEVRTTRTFGESSKSSYELIVVAHDHGKTSLSASALVLIYLS----PAL-DAQES 671 + + GEVRT + +L++V D G LS S +L+ L P + D +ES Sbjct: 621 VSRYAGEVRTAVPI-PADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPVVPDLRES 679 Query: 672 M----GSVNLSLIFIIALGSIAGILFVTMIFVAIKCKR 705 G L+L ++L +I + F + + + KC R Sbjct: 680 SAPREGESRLTLYLAVSLVAICFVSFGSFVALLSKCLR 717 >gi|14165413 protocadherin alpha 4 isoform 2 precursor [Homo sapiens] Length = 798 Score = 489 bits (1260), Expect = e-138 Identities = 283/754 (37%), Positives = 426/754 (56%), Gaps = 36/754 (4%) Query: 2 ESLLLPVLLLLAILWTQAAALINLKYSVEEEQRAGTVIANVAKDAREAGFALDPRQASAF 61 ES L +LLLL W L YSV EE + GT + +A+D L PR F Sbjct: 10 ESRRLLLLLLLLAAWEAGNG--QLHYSVSEEAKHGTFVGRIAQDLGLELAELVPR---LF 64 Query: 62 RVVSNSAPHLVDINPSSGLLVTKQKIDRDLLCRQSPKCIISLEVM-SSSMEICVIKVEIK 120 RV S L+++N +G+L +IDR+ LCR+S +C I LEV+ +++ + VE++ Sbjct: 65 RVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVR 124 Query: 121 DLNDNAPSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKT 180 D+NDN P FPA Q L I+E+ +R PL+ A D D G + TY L+PNE F LE Sbjct: 125 DINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPP 184 Query: 181 RGDGSRFAELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNPVFSE 240 + + L++ KSLDRE +TA DGG P GTV L I V D+NDN P F Sbjct: 185 DDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDR 244 Query: 241 STYAVSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTV 300 + Y V + EN P T VI+LNASD DEG NG +VYSF ++ + F IDP +G + V Sbjct: 245 TIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIV 304 Query: 301 TGALDYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSE 360 G +D+EE YE+ V+ D G + HC+V V V D NDN P + S++ + + E Sbjct: 305 KGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLS---LPIRE 361 Query: 361 SAPPGYVIALVRVSDRDSGLNGRVQCRLLGNVPFRL-QEYESFSTILVDGRLDREQHDQY 419 AP G VIAL+ VSD+D G+NG V C L +VPF+L ++++ ++++D LDRE Y Sbjct: 362 DAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAY 421 Query: 420 NLTIQARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARD 479 L + ARDGG P L + S +V + D NDN P F++P Y V V+ENN PG ++ +VSA D Sbjct: 422 ELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWD 481 Query: 480 PDLGLNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGG 539 D N VSY +V +V + + +YVS++ SG +YAL+ +HE+ + +F+V A+D G Sbjct: 482 ADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAG 541 Query: 540 LPSLQSNATVRVIILDVNDNTPVITAPPL--INGTAEVYIPRNSGIGYLVTVVKAEDYDE 597 +P L SN T++V +LD NDN P + AP G +P + G+G++V V+A D D Sbjct: 542 VPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADS 601 Query: 598 GENGRVTYDMTEGDRGF---FEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGKTSLSA 654 G N ++Y++ G G F + GE+ TTR E+ + L+V+ DHG+ +L+A Sbjct: 602 GYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTA 661 Query: 655 SALVLIYL-----SPALDAQESMGS-------VNLSLIFIIALGSIAGILFVT-MIFVAI 701 +A VL+ L +P ++ +G+ V++++ IIA+ +++ +L +T +++ A+ Sbjct: 662 TATVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTAL 721 Query: 702 KCK--------RDNKEIRTYNCRIAEYSYGHQKK 727 +C K + + +SY Q++ Sbjct: 722 RCSALPTEGACAPGKPTLVCSSAVGSWSYSQQRR 755 >gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens] Length = 947 Score = 489 bits (1260), Expect = e-138 Identities = 283/754 (37%), Positives = 426/754 (56%), Gaps = 36/754 (4%) Query: 2 ESLLLPVLLLLAILWTQAAALINLKYSVEEEQRAGTVIANVAKDAREAGFALDPRQASAF 61 ES L +LLLL W L YSV EE + GT + +A+D L PR F Sbjct: 10 ESRRLLLLLLLLAAWEAGNG--QLHYSVSEEAKHGTFVGRIAQDLGLELAELVPR---LF 64 Query: 62 RVVSNSAPHLVDINPSSGLLVTKQKIDRDLLCRQSPKCIISLEVM-SSSMEICVIKVEIK 120 RV S L+++N +G+L +IDR+ LCR+S +C I LEV+ +++ + VE++ Sbjct: 65 RVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVR 124 Query: 121 DLNDNAPSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKT 180 D+NDN P FPA Q L I+E+ +R PL+ A D D G + TY L+PNE F LE Sbjct: 125 DINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPP 184 Query: 181 RGDGSRFAELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNPVFSE 240 + + L++ KSLDRE +TA DGG P GTV L I V D+NDN P F Sbjct: 185 DDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDR 244 Query: 241 STYAVSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTV 300 + Y V + EN P T VI+LNASD DEG NG +VYSF ++ + F IDP +G + V Sbjct: 245 TIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIV 304 Query: 301 TGALDYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSE 360 G +D+EE YE+ V+ D G + HC+V V V D NDN P + S++ + + E Sbjct: 305 KGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLS---LPIRE 361 Query: 361 SAPPGYVIALVRVSDRDSGLNGRVQCRLLGNVPFRL-QEYESFSTILVDGRLDREQHDQY 419 AP G VIAL+ VSD+D G+NG V C L +VPF+L ++++ ++++D LDRE Y Sbjct: 362 DAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAY 421 Query: 420 NLTIQARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARD 479 L + ARDGG P L + S +V + D NDN P F++P Y V V+ENN PG ++ +VSA D Sbjct: 422 ELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWD 481 Query: 480 PDLGLNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGG 539 D N VSY +V +V + + +YVS++ SG +YAL+ +HE+ + +F+V A+D G Sbjct: 482 ADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAG 541 Query: 540 LPSLQSNATVRVIILDVNDNTPVITAPPL--INGTAEVYIPRNSGIGYLVTVVKAEDYDE 597 +P L SN T++V +LD NDN P + AP G +P + G+G++V V+A D D Sbjct: 542 VPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADS 601 Query: 598 GENGRVTYDMTEGDRGF---FEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGKTSLSA 654 G N ++Y++ G G F + GE+ TTR E+ + L+V+ DHG+ +L+A Sbjct: 602 GYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTA 661 Query: 655 SALVLIYL-----SPALDAQESMGS-------VNLSLIFIIALGSIAGILFVT-MIFVAI 701 +A VL+ L +P ++ +G+ V++++ IIA+ +++ +L +T +++ A+ Sbjct: 662 TATVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTAL 721 Query: 702 KCK--------RDNKEIRTYNCRIAEYSYGHQKK 727 +C K + + +SY Q++ Sbjct: 722 RCSALPTEGACAPGKPTLVCSSAVGSWSYSQQRR 755 >gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo sapiens] Length = 814 Score = 489 bits (1258), Expect = e-138 Identities = 279/749 (37%), Positives = 433/749 (57%), Gaps = 36/749 (4%) Query: 6 LPVLLLLAILWTQAAALINLKYSVEEEQRAGTVIANVAKDAREAGFALDPRQASAFRVVS 65 L +LLLL W + L YSV EE + GT + +A+D L PR FRV S Sbjct: 14 LLLLLLLLAAWKVGSG--QLHYSVPEEAKHGTFVGRIAQDLGLELAELVPR---LFRVAS 68 Query: 66 NSAPHLVDINPSSGLLVTKQKIDRDLLCRQSPKCIISLEVM-SSSMEICVIKVEIKDLND 124 L++++ +G+L +IDR+ LC +S +C I LEV+ +++ + VE+KD+ND Sbjct: 69 KRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVND 128 Query: 125 NAPSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKTRGDG 184 N P F +L +SE+ P +R PL+ A D D G+ V TY L+ ++ F L++ ++ D Sbjct: 129 NPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDE 188 Query: 185 SRFAELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNPVFSESTYA 244 ++ ELV+ KSLDRE + +TA DGG P GTV L + V D NDN P F +S Y Sbjct: 189 NKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE 248 Query: 245 VSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTVTGAL 304 V + EN+ T VI+LNASDPDEG NG + YSF V + F ID ++G + + G L Sbjct: 249 VRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNL 308 Query: 305 DYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSESAPP 364 D+E+ ++Y++ + A D G + HC V V +LD NDN P I L S++ + V E A Sbjct: 309 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLS---LPVREDAQF 365 Query: 365 GYVIALVRVSDRDSGLNGRVQCRLLGNVPFRL-QEYESFSTILVDGRLDREQHDQYNLTI 423 G VIAL+ V+D DSG NG+V C L+ +VPF+L ++++ ++++D LDRE+ Y L + Sbjct: 366 GTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVV 425 Query: 424 QARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDPDLG 483 ARDGG P L + S +V + D NDN P F++P Y V V+ENN PG ++ +VSARD D Sbjct: 426 TARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQ 485 Query: 484 LNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGGLPSL 543 N VSY +V +V + + +Y+S++ SG +YAL+ +HE+ + +F+V A+D G+P L Sbjct: 486 ENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPL 545 Query: 544 QSNATVRVIILDVNDNTPVITAPPL--INGTAEVYIPRNSGIGYLVTVVKAEDYDEGENG 601 SN T++V +LD NDN P + P + G A +PR+ G G++V V+A D D G N Sbjct: 546 GSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNA 605 Query: 602 RVTYDM---TEGDRGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGKTSLSASALV 658 ++Y++ R F + GE+ TTR E+ + L+V+ DHG+ +L+A+A V Sbjct: 606 WLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATV 665 Query: 659 LIYL-----SPALDAQESMG-------SVNLSLIFIIALGSIAGILFVT-MIFVAIKCK- 704 L+ L +P +++S G V++++ IIA+ +++ +L +T +++ A++C Sbjct: 666 LVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA 725 Query: 705 -------RDNKEIRTYNCRIAEYSYGHQK 726 R K + + +SY Q+ Sbjct: 726 LPTEGGCRAGKPTLVCSSAVGSWSYSQQQ 754 >gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens] Length = 950 Score = 489 bits (1258), Expect = e-138 Identities = 279/749 (37%), Positives = 433/749 (57%), Gaps = 36/749 (4%) Query: 6 LPVLLLLAILWTQAAALINLKYSVEEEQRAGTVIANVAKDAREAGFALDPRQASAFRVVS 65 L +LLLL W + L YSV EE + GT + +A+D L PR FRV S Sbjct: 14 LLLLLLLLAAWKVGSG--QLHYSVPEEAKHGTFVGRIAQDLGLELAELVPR---LFRVAS 68 Query: 66 NSAPHLVDINPSSGLLVTKQKIDRDLLCRQSPKCIISLEVM-SSSMEICVIKVEIKDLND 124 L++++ +G+L +IDR+ LC +S +C I LEV+ +++ + VE+KD+ND Sbjct: 69 KRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVND 128 Query: 125 NAPSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKTRGDG 184 N P F +L +SE+ P +R PL+ A D D G+ V TY L+ ++ F L++ ++ D Sbjct: 129 NPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDE 188 Query: 185 SRFAELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNPVFSESTYA 244 ++ ELV+ KSLDRE + +TA DGG P GTV L + V D NDN P F +S Y Sbjct: 189 NKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE 248 Query: 245 VSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTVTGAL 304 V + EN+ T VI+LNASDPDEG NG + YSF V + F ID ++G + + G L Sbjct: 249 VRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNL 308 Query: 305 DYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSESAPP 364 D+E+ ++Y++ + A D G + HC V V +LD NDN P I L S++ + V E A Sbjct: 309 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLS---LPVREDAQF 365 Query: 365 GYVIALVRVSDRDSGLNGRVQCRLLGNVPFRL-QEYESFSTILVDGRLDREQHDQYNLTI 423 G VIAL+ V+D DSG NG+V C L+ +VPF+L ++++ ++++D LDRE+ Y L + Sbjct: 366 GTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVV 425 Query: 424 QARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDPDLG 483 ARDGG P L + S +V + D NDN P F++P Y V V+ENN PG ++ +VSARD D Sbjct: 426 TARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQ 485 Query: 484 LNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGGLPSL 543 N VSY +V +V + + +Y+S++ SG +YAL+ +HE+ + +F+V A+D G+P L Sbjct: 486 ENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPL 545 Query: 544 QSNATVRVIILDVNDNTPVITAPPL--INGTAEVYIPRNSGIGYLVTVVKAEDYDEGENG 601 SN T++V +LD NDN P + P + G A +PR+ G G++V V+A D D G N Sbjct: 546 GSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNA 605 Query: 602 RVTYDM---TEGDRGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGKTSLSASALV 658 ++Y++ R F + GE+ TTR E+ + L+V+ DHG+ +L+A+A V Sbjct: 606 WLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATV 665 Query: 659 LIYL-----SPALDAQESMG-------SVNLSLIFIIALGSIAGILFVT-MIFVAIKCK- 704 L+ L +P +++S G V++++ IIA+ +++ +L +T +++ A++C Sbjct: 666 LVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA 725 Query: 705 -------RDNKEIRTYNCRIAEYSYGHQK 726 R K + + +SY Q+ Sbjct: 726 LPTEGGCRAGKPTLVCSSAVGSWSYSQQQ 754 >gi|14165390 protocadherin alpha 6 isoform 2 precursor [Homo sapiens] Length = 803 Score = 488 bits (1255), Expect = e-137 Identities = 280/754 (37%), Positives = 436/754 (57%), Gaps = 38/754 (5%) Query: 2 ESLLLPVLLLLAILWTQAAALINLKYSVEEEQRAGTVIANVAKDAREAGFALDPRQASAF 61 + LLLP+LLL A W + L YSV EE + GT + +A+D L PR F Sbjct: 12 QCLLLPLLLLAA--WKVGSG--QLHYSVPEEAKHGTFVGRIAQDLGLELAELVPR---LF 64 Query: 62 RVVSNSAPHLVDINPSSGLLVTKQKIDRDLLCRQSPKCIISLEVM-SSSMEICVIKVEIK 120 R+ S L+++N +G+L +IDR+ LC +S +C I LEV+ +++ + VE++ Sbjct: 65 RMASKDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVR 124 Query: 121 DLNDNAPSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKT 180 D+NDN P FP + + I E+ P + PL+ A D D GS + TY+L+ +E FGL++K Sbjct: 125 DINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKI 184 Query: 181 RGDGSRFAELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNPVFSE 240 D ++ L+++KSLDRE ++ +TA DGG P GTV L + V D NDN P F + Sbjct: 185 NSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQ 244 Query: 241 STYAVSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTV 300 S Y V + EN+ T VIRLNASD DEG NG + YSF V + F ID ++G + + Sbjct: 245 SEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVI 304 Query: 301 TGALDYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSE 360 G LD+E+ ++Y++ + A D G + HC V V +LD NDN P I L S++ + V E Sbjct: 305 RGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLS---LPVRE 361 Query: 361 SAPPGYVIALVRVSDRDSGLNGRVQCRLLGNVPFRL-QEYESFSTILVDGRLDREQHDQY 419 A G VIAL+ V+D DSG NG+V C L +VPF+L ++++ ++++D LDRE Y Sbjct: 362 DAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAY 421 Query: 420 NLTIQARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARD 479 L + ARDGG P L + S +V + D NDN P F++P Y V V+ENN PG ++ +VSARD Sbjct: 422 ELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARD 481 Query: 480 PDLGLNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGG 539 D N VSY +V +V + + +Y+S++ SG +YAL+ +HE+ + +F+V A+D G Sbjct: 482 ADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAG 541 Query: 540 LPSLQSNATVRVIILDVNDNTPVITAPPL--INGTAEVYIPRNSGIGYLVTVVKAEDYDE 597 +P L SN T++V +LD NDN P + AP + G +PR+ G G +V V+A D D Sbjct: 542 VPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADS 601 Query: 598 GENGRVTYDM---TEGDRGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGKTSLSA 654 G N ++Y++ R F + GE+ TTR E+ + L+V+ DHG+ +L+A Sbjct: 602 GYNAWLSYELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTA 661 Query: 655 SALVLIYL-----SPALDAQESMGS-------VNLSLIFIIALGSIAGILFVT-MIFVAI 701 +A VL+ L +P ++ S+G+ V++++ IIA+ +++ +L +T +++ A+ Sbjct: 662 TATVLVSLVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTAL 721 Query: 702 KCKRD--------NKEIRTYNCRIAEYSYGHQKK 727 +C +K + + +SY Q++ Sbjct: 722 RCSAPPTEGACTADKPTLVCSSAVGSWSYSQQRR 755 >gi|9256592 protocadherin alpha 6 isoform 1 precursor [Homo sapiens] Length = 950 Score = 488 bits (1255), Expect = e-137 Identities = 280/754 (37%), Positives = 436/754 (57%), Gaps = 38/754 (5%) Query: 2 ESLLLPVLLLLAILWTQAAALINLKYSVEEEQRAGTVIANVAKDAREAGFALDPRQASAF 61 + LLLP+LLL A W + L YSV EE + GT + +A+D L PR F Sbjct: 12 QCLLLPLLLLAA--WKVGSG--QLHYSVPEEAKHGTFVGRIAQDLGLELAELVPR---LF 64 Query: 62 RVVSNSAPHLVDINPSSGLLVTKQKIDRDLLCRQSPKCIISLEVM-SSSMEICVIKVEIK 120 R+ S L+++N +G+L +IDR+ LC +S +C I LEV+ +++ + VE++ Sbjct: 65 RMASKDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVR 124 Query: 121 DLNDNAPSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKT 180 D+NDN P FP + + I E+ P + PL+ A D D GS + TY+L+ +E FGL++K Sbjct: 125 DINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKI 184 Query: 181 RGDGSRFAELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNPVFSE 240 D ++ L+++KSLDRE ++ +TA DGG P GTV L + V D NDN P F + Sbjct: 185 NSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQ 244 Query: 241 STYAVSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTV 300 S Y V + EN+ T VIRLNASD DEG NG + YSF V + F ID ++G + + Sbjct: 245 SEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVI 304 Query: 301 TGALDYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSE 360 G LD+E+ ++Y++ + A D G + HC V V +LD NDN P I L S++ + V E Sbjct: 305 RGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLS---LPVRE 361 Query: 361 SAPPGYVIALVRVSDRDSGLNGRVQCRLLGNVPFRL-QEYESFSTILVDGRLDREQHDQY 419 A G VIAL+ V+D DSG NG+V C L +VPF+L ++++ ++++D LDRE Y Sbjct: 362 DAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAY 421 Query: 420 NLTIQARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARD 479 L + ARDGG P L + S +V + D NDN P F++P Y V V+ENN PG ++ +VSARD Sbjct: 422 ELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARD 481 Query: 480 PDLGLNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGG 539 D N VSY +V +V + + +Y+S++ SG +YAL+ +HE+ + +F+V A+D G Sbjct: 482 ADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAG 541 Query: 540 LPSLQSNATVRVIILDVNDNTPVITAPPL--INGTAEVYIPRNSGIGYLVTVVKAEDYDE 597 +P L SN T++V +LD NDN P + AP + G +PR+ G G +V V+A D D Sbjct: 542 VPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADS 601 Query: 598 GENGRVTYDM---TEGDRGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGKTSLSA 654 G N ++Y++ R F + GE+ TTR E+ + L+V+ DHG+ +L+A Sbjct: 602 GYNAWLSYELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTA 661 Query: 655 SALVLIYL-----SPALDAQESMGS-------VNLSLIFIIALGSIAGILFVT-MIFVAI 701 +A VL+ L +P ++ S+G+ V++++ IIA+ +++ +L +T +++ A+ Sbjct: 662 TATVLVSLVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTAL 721 Query: 702 KCKRD--------NKEIRTYNCRIAEYSYGHQKK 727 +C +K + + +SY Q++ Sbjct: 722 RCSAPPTEGACTADKPTLVCSSAVGSWSYSQQRR 755 >gi|14165419 protocadherin alpha 7 isoform 2 precursor [Homo sapiens] Length = 789 Score = 486 bits (1250), Expect = e-137 Identities = 277/722 (38%), Positives = 414/722 (57%), Gaps = 26/722 (3%) Query: 8 VLLLLAILWTQAAALINLKYSVEEEQRAGTVIANVAKDAREAGFALDPRQASAFRVVSNS 67 +LL + IL A L YSV EE + G + +A+D L PR FR V Sbjct: 14 LLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPR---LFRAVCKF 70 Query: 68 APHLVDINPSSGLLVTKQKIDRDLLCRQSPKCIISLEVM-SSSMEICVIKVEIKDLNDNA 126 L+++N +G+L +IDR+ LC +S +C I LEV+ +++ + VE+KD+NDN Sbjct: 71 RGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDNP 130 Query: 127 PSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKTRGDGSR 186 P FPA Q L I+E+ +R PL+ A D D G + TY L+PNE F L++ T + Sbjct: 131 PVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVK 190 Query: 187 FAELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNPVFSESTYAVS 246 LV+ K LDRE +TA DGG P GTV L I V D+NDN PVF + Y V Sbjct: 191 PLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVK 250 Query: 247 VPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTVTGALDY 306 +PEN T VI NASD DEG NG ++YSF V+ + F +DP SG +TV G +D+ Sbjct: 251 LPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDF 310 Query: 307 EEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSESAPPGY 366 EE +++ V+A D G + HC V V V+D NDN P + L S++ + + E A PG Sbjct: 311 EESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLS---LPIPEDAQPGT 367 Query: 367 VIALVRVSDRDSGLNGRVQCRLLGNVPFRL-QEYESFSTILVDGRLDREQHDQYNLTIQA 425 VI L+ V DRD G+NG+V C L VPF+L ++++ ++++D LDRE Y L + A Sbjct: 368 VITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTA 427 Query: 426 RDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDPDLGLN 485 RDGG P L + S +V + D NDN P F++P Y V V+ENN PG ++ +VSA D D N Sbjct: 428 RDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKN 487 Query: 486 GSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGGLPSLQS 545 VSY +V +V + + +YVS++ SG +YAL+ +HE+ + +F+V A+D G+P L S Sbjct: 488 ALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGS 547 Query: 546 NATVRVIILDVNDNTPVITAPPL--INGTAEVYIPRNSGIGYLVTVVKAEDYDEGENGRV 603 N T++V +LD NDN P + AP + G +PR+ G G++V V+A D D G N + Sbjct: 548 NVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWL 607 Query: 604 TYDMTEGDRGF---FEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGKTSLSASALVLI 660 +Y++ G F + GE+ TTR E+ + L+V+ DHG+ SL+A+A VL+ Sbjct: 608 SYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLV 667 Query: 661 YL-----SPALDAQESMG-------SVNLSLIFIIALGSIAGILFVT-MIFVAIKCKRDN 707 L +P ++ S+G V++++ IIA+ +++ +L +T +++ A++C + Sbjct: 668 SLVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPS 727 Query: 708 KE 709 E Sbjct: 728 SE 729 >gi|9256594 protocadherin alpha 7 isoform 1 precursor [Homo sapiens] Length = 937 Score = 486 bits (1250), Expect = e-137 Identities = 277/722 (38%), Positives = 414/722 (57%), Gaps = 26/722 (3%) Query: 8 VLLLLAILWTQAAALINLKYSVEEEQRAGTVIANVAKDAREAGFALDPRQASAFRVVSNS 67 +LL + IL A L YSV EE + G + +A+D L PR FR V Sbjct: 14 LLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPR---LFRAVCKF 70 Query: 68 APHLVDINPSSGLLVTKQKIDRDLLCRQSPKCIISLEVM-SSSMEICVIKVEIKDLNDNA 126 L+++N +G+L +IDR+ LC +S +C I LEV+ +++ + VE+KD+NDN Sbjct: 71 RGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDNP 130 Query: 127 PSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKTRGDGSR 186 P FPA Q L I+E+ +R PL+ A D D G + TY L+PNE F L++ T + Sbjct: 131 PVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVK 190 Query: 187 FAELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNPVFSESTYAVS 246 LV+ K LDRE +TA DGG P GTV L I V D+NDN PVF + Y V Sbjct: 191 PLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVK 250 Query: 247 VPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTVTGALDY 306 +PEN T VI NASD DEG NG ++YSF V+ + F +DP SG +TV G +D+ Sbjct: 251 LPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDF 310 Query: 307 EEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSESAPPGY 366 EE +++ V+A D G + HC V V V+D NDN P + L S++ + + E A PG Sbjct: 311 EESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLS---LPIPEDAQPGT 367 Query: 367 VIALVRVSDRDSGLNGRVQCRLLGNVPFRL-QEYESFSTILVDGRLDREQHDQYNLTIQA 425 VI L+ V DRD G+NG+V C L VPF+L ++++ ++++D LDRE Y L + A Sbjct: 368 VITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTA 427 Query: 426 RDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDPDLGLN 485 RDGG P L + S +V + D NDN P F++P Y V V+ENN PG ++ +VSA D D N Sbjct: 428 RDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKN 487 Query: 486 GSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGGLPSLQS 545 VSY +V +V + + +YVS++ SG +YAL+ +HE+ + +F+V A+D G+P L S Sbjct: 488 ALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGS 547 Query: 546 NATVRVIILDVNDNTPVITAPPL--INGTAEVYIPRNSGIGYLVTVVKAEDYDEGENGRV 603 N T++V +LD NDN P + AP + G +PR+ G G++V V+A D D G N + Sbjct: 548 NVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWL 607 Query: 604 TYDMTEGDRGF---FEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGKTSLSASALVLI 660 +Y++ G F + GE+ TTR E+ + L+V+ DHG+ SL+A+A VL+ Sbjct: 608 SYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLV 667 Query: 661 YL-----SPALDAQESMG-------SVNLSLIFIIALGSIAGILFVT-MIFVAIKCKRDN 707 L +P ++ S+G V++++ IIA+ +++ +L +T +++ A++C + Sbjct: 668 SLVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPS 727 Query: 708 KE 709 E Sbjct: 728 SE 729 >gi|11128035 protocadherin gamma subfamily B, 2 isoform 1 precursor [Homo sapiens] Length = 931 Score = 486 bits (1250), Expect = e-137 Identities = 272/708 (38%), Positives = 412/708 (58%), Gaps = 29/708 (4%) Query: 4 LLLPVLLLLAILWTQAAALINLKYSVEEEQRAGTVIANVAKDAREAGFALDPRQASAFRV 63 +LLP LL L A + ++YS+ EE +V+ N+AKD L R A ++ Sbjct: 16 VLLPFLLSLF----PGALPVQIRYSIPEELAKNSVVGNLAKD-----LGLSVRDLPARKL 66 Query: 64 VSNSAPHLVDINPSSGLLVTKQKIDRDLLCRQSPKCIISLEVMSSS-MEICVIKVEIKDL 122 ++ +NP SG L+ +IDR+ +C + P C++ + ++ + + I I V ++D+ Sbjct: 67 RVSAEKEYFTVNPESGDLLVSDRIDREQICGKQPLCVLDFDTVAENPLNIFYIAVIVQDI 126 Query: 123 NDNAPSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKTRG 182 NDN P F +I L+I E+ PGT PLD A D D G +Q Y L NE F L K Sbjct: 127 NDNTPLFKQTKINLKIGESTKPGTTFPLDPALDSDVGPNSLQRYHLNDNEYFDLAEKQTP 186 Query: 183 DGSRFAELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNPVFSEST 242 DG ++ EL+++ SLDRE S + +TA+DGGDPP+ GT + IKVTD+NDN PVFS+ Sbjct: 187 DGRKYPELILKHSLDREEHSLHQLVLTAVDGGDPPQSGTTQIRIKVTDANDNPPVFSQDV 246 Query: 243 YAVSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTVTG 302 Y V++ E+ PP V+++ A+D DEG N ++ YSF+ V+++ + F ++ +G +T Sbjct: 247 YRVTLREDVPPGFFVLQVTATDRDEGINAEITYSFHN-VDEQVKHFFNLNEKTGEITTKD 305 Query: 303 ALDYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSESA 362 LD+E Y L ++AKD P + AHC + V +LD ND P + + SV++ L E + Sbjct: 306 DLDFEIASSYTLSIEAKD--PGDLAAHCSIQVEILDDNDCAPEVIVTSVSTPL---PEDS 360 Query: 363 PPGYVIALVRVSDRDSGLNGRVQCRLLGNVPFRLQ-EYESFSTILVDGRLDREQHDQYNL 421 PPG VIAL++ DRDSG NG V C++LGN F L+ +++ ++ DG LDRE+ +YNL Sbjct: 361 PPGTVIALIKTRDRDSGENGEVYCQVLGNAKFILKSSSKNYYKLVTDGALDREEIPEYNL 420 Query: 422 TIQARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDPD 481 TI A DGG P L S+ T+ I+D NDN P F + Y V V ENN PGA + +SA DPD Sbjct: 421 TITATDGGKPPLSSSIIVTLHISDVNDNAPVFQQTSYMVHVAENNPPGASIAQISASDPD 480 Query: 482 LGLNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGGLP 541 LG +G VSY IV S ++ + +YVS++ SG ++A R+F+HEQ +AFE + A+D G P Sbjct: 481 LGPSGQVSYSIVASDLKPREILSYVSVSAQSGVVFAQRAFDHEQLRAFELTLQARDQGSP 540 Query: 542 SLQSNATVRVIILDVNDNTPVITAPPLINGTAEVY--IPRNSGIGYLVTVVKAEDYDEGE 599 +L +N ++RV++ D+NDN P + P L + ++ +PR + GYLVT V A D D G Sbjct: 541 ALSANVSLRVLVGDLNDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGH 600 Query: 600 NGRVTYDMTE-GDRGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGKTSLSASALV 658 N ++Y + + + G F + GEVRT R G+ + L+V D G+ LSA+A + Sbjct: 601 NAWLSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATL 660 Query: 659 LIYLSPALD---------AQESMGSVNLSLIFIIALGSIAGILFVTMI 697 + + +L + S L ++AL I+ + F+ +I Sbjct: 661 HLIFADSLQEVLPDLSDRREPSDPQAKLQFYLVVALALISVLFFLAVI 708 >gi|14270493 protocadherin gamma subfamily B, 2 isoform 2 precursor [Homo sapiens] Length = 811 Score = 486 bits (1250), Expect = e-137 Identities = 272/708 (38%), Positives = 412/708 (58%), Gaps = 29/708 (4%) Query: 4 LLLPVLLLLAILWTQAAALINLKYSVEEEQRAGTVIANVAKDAREAGFALDPRQASAFRV 63 +LLP LL L A + ++YS+ EE +V+ N+AKD L R A ++ Sbjct: 16 VLLPFLLSLF----PGALPVQIRYSIPEELAKNSVVGNLAKD-----LGLSVRDLPARKL 66 Query: 64 VSNSAPHLVDINPSSGLLVTKQKIDRDLLCRQSPKCIISLEVMSSS-MEICVIKVEIKDL 122 ++ +NP SG L+ +IDR+ +C + P C++ + ++ + + I I V ++D+ Sbjct: 67 RVSAEKEYFTVNPESGDLLVSDRIDREQICGKQPLCVLDFDTVAENPLNIFYIAVIVQDI 126 Query: 123 NDNAPSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKTRG 182 NDN P F +I L+I E+ PGT PLD A D D G +Q Y L NE F L K Sbjct: 127 NDNTPLFKQTKINLKIGESTKPGTTFPLDPALDSDVGPNSLQRYHLNDNEYFDLAEKQTP 186 Query: 183 DGSRFAELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNPVFSEST 242 DG ++ EL+++ SLDRE S + +TA+DGGDPP+ GT + IKVTD+NDN PVFS+ Sbjct: 187 DGRKYPELILKHSLDREEHSLHQLVLTAVDGGDPPQSGTTQIRIKVTDANDNPPVFSQDV 246 Query: 243 YAVSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTVTG 302 Y V++ E+ PP V+++ A+D DEG N ++ YSF+ V+++ + F ++ +G +T Sbjct: 247 YRVTLREDVPPGFFVLQVTATDRDEGINAEITYSFHN-VDEQVKHFFNLNEKTGEITTKD 305 Query: 303 ALDYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSESA 362 LD+E Y L ++AKD P + AHC + V +LD ND P + + SV++ L E + Sbjct: 306 DLDFEIASSYTLSIEAKD--PGDLAAHCSIQVEILDDNDCAPEVIVTSVSTPL---PEDS 360 Query: 363 PPGYVIALVRVSDRDSGLNGRVQCRLLGNVPFRLQ-EYESFSTILVDGRLDREQHDQYNL 421 PPG VIAL++ DRDSG NG V C++LGN F L+ +++ ++ DG LDRE+ +YNL Sbjct: 361 PPGTVIALIKTRDRDSGENGEVYCQVLGNAKFILKSSSKNYYKLVTDGALDREEIPEYNL 420 Query: 422 TIQARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDPD 481 TI A DGG P L S+ T+ I+D NDN P F + Y V V ENN PGA + +SA DPD Sbjct: 421 TITATDGGKPPLSSSIIVTLHISDVNDNAPVFQQTSYMVHVAENNPPGASIAQISASDPD 480 Query: 482 LGLNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGGLP 541 LG +G VSY IV S ++ + +YVS++ SG ++A R+F+HEQ +AFE + A+D G P Sbjct: 481 LGPSGQVSYSIVASDLKPREILSYVSVSAQSGVVFAQRAFDHEQLRAFELTLQARDQGSP 540 Query: 542 SLQSNATVRVIILDVNDNTPVITAPPLINGTAEVY--IPRNSGIGYLVTVVKAEDYDEGE 599 +L +N ++RV++ D+NDN P + P L + ++ +PR + GYLVT V A D D G Sbjct: 541 ALSANVSLRVLVGDLNDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGH 600 Query: 600 NGRVTYDMTE-GDRGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGKTSLSASALV 658 N ++Y + + + G F + GEVRT R G+ + L+V D G+ LSA+A + Sbjct: 601 NAWLSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATL 660 Query: 659 LIYLSPALD---------AQESMGSVNLSLIFIIALGSIAGILFVTMI 697 + + +L + S L ++AL I+ + F+ +I Sbjct: 661 HLIFADSLQEVLPDLSDRREPSDPQAKLQFYLVVALALISVLFFLAVI 708 >gi|7706113 protocadherin 12 precursor [Homo sapiens] Length = 1184 Score = 485 bits (1249), Expect = e-137 Identities = 293/768 (38%), Positives = 436/768 (56%), Gaps = 55/768 (7%) Query: 18 QAAALINLKYSVEEEQRAGTVIANVAKDAREAGFALDPRQA-SAFRVVSNSAPHLVDINP 76 Q + +KY V EE +GTVI +++ E G RQA +AF+V+ + ++ Sbjct: 25 QEVTTLTVKYQVSEEVPSGTVIGKLSQ---ELGREERRRQAGAAFQVLQLPQALPIQVDS 81 Query: 77 SSGLLVTKQKIDRDLLCRQSPKCIISLEVMSSSMEICVIKVEIK--DLNDNAPSFPAAQI 134 GLL T +++DR+ LCRQ C++S +V+++ ++ +I VEI+ D+ND+ P FP + Sbjct: 82 EEGLLSTGRRLDREQLCRQWDPCLVSFDVLATG-DLALIHVEIQVLDINDHQPRFPKGEQ 140 Query: 135 ELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKTRGDGSRFAELVVEK 194 ELEISE+AS TRIPLD A DPD+G + TY L+P+E F L++ D ++ AEL+V K Sbjct: 141 ELEISESASLRTRIPLDRALDPDTGPNTLHTYTLSPSEHFALDVIVGPDETKHAELIVVK 200 Query: 195 SLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNPVFSESTYAVSVPENSPPN 254 LDRE S + +TA D G+PP+ GT + + V DSNDN+P F+ES+ A+ + E++ P Sbjct: 201 ELDREIHSFFDLVLTAYDNGNPPKSGTSLVKVNVLDSNDNSPAFAESSLALEIQEDAAPG 260 Query: 255 TPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTVTGALDYEEGHVYEL 314 T +I+L A+DPD+G NG+V + ++ + F ID +G V + LDYE+ YE+ Sbjct: 261 TLLIKLTATDPDQGPNGEVEFFLSKHMPPEVLDTFSIDAKTGQVILRRPLDYEKNPAYEV 320 Query: 315 DVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSESAPPGYVIALVRVS 374 DVQA+DLGPN IPAHCKV + VLD NDN P I++ + + VSE+ P IALV Sbjct: 321 DVQARDLGPNPIPAHCKVLIKVLDVNDNIPSIHVTWASQPSL-VSEALPKDSFIALVMAD 379 Query: 375 DRDSGLNGRVQCRL---LGNVPFRLQEYESFS-TILVDGRLDREQHDQYNLTIQARDGGV 430 D DSG NG V C L LG+ FRL+ + +L + LDREQ +Y LT+ A+D G+ Sbjct: 380 DLDSGHNGLVHCWLSQELGH--FRLKRTNGNTYMLLTNATLDREQWPKYTLTLLAQDQGL 437 Query: 431 PMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDPDLGLNGSVSY 490 L + K ++ I+D NDN P F K Y+V +ENN P +L+++ A D DLG+NG VSY Sbjct: 438 QPLSAKKQLSIQISDINDNAPVFEKSRYEVSTRENNLPSLHLITIKAHDADLGINGKVSY 497 Query: 491 QIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGGLPSLQSNATVR 550 +I +D PV V+I+ N+G++ A RS N+E+ FEF+V+A+D G P L S+ +V Sbjct: 498 RI-----QDSPVAHLVAIDSNTGEVTAQRSLNYEEMAGFEFQVIAEDSGQPMLASSVSVW 552 Query: 551 VIILDVNDNTPVITAPPLINGTAEVYIPRNSGIG-------------------------- 584 V +LD NDN P + P L +G A + + N+ G Sbjct: 553 VSLLDANDNAPEVVQPVLSDGKASLSVLVNASTGHLLVPIETPNGLGPAGTDTPPLATHS 612 Query: 585 ---YLVTVVKAEDYDEGENGRVTYDMTEGDRG-FFEIDQVNGEVRTTRTFGESS-KSSYE 639 +L+T + A D D G NG Y + G+ F ++ G++ T S S +E Sbjct: 613 SRPFLLTTIVARDADSGANGEPLYSIRSGNEAHLFILNPHTGQLFVNVTNASSLIGSEWE 672 Query: 640 LIVVAHDHGKTSLSASALVLIYLSPALD----AQESMGSVNLSLIFIIALGSIAGILFVT 695 L +V D G L AL+ + ++D + G++++S++ +I L + GI + Sbjct: 673 LEIVVEDQGSPPLQTRALLRVMFVTSVDHLRDSARKPGALSMSMLTVICLAVLLGIFGLI 732 Query: 696 MIFVAIKCKRDNKEIRTYNCRIAEYSYGHQKKSSKKKKISKNDIRLVP 743 + C+ + K+ R YNCR AE +Y Q K +K I K DI LVP Sbjct: 733 LALFMSICRTEKKDNRAYNCREAESTYRQQPK-RPQKHIQKADIHLVP 779 >gi|14165387 protocadherin alpha 11 isoform 2 precursor [Homo sapiens] Length = 810 Score = 483 bits (1243), Expect = e-136 Identities = 274/711 (38%), Positives = 413/711 (58%), Gaps = 28/711 (3%) Query: 6 LPVLLLLAILWTQAAALINLKYSVEEEQRAGTVIANVAKDAREAGFALDPRQASAFRVVS 65 L + LLL W + L YSV EE + GT + +A+D G L FRV S Sbjct: 14 LQLWLLLLEFWEVGSG--QLHYSVSEEAKHGTFVGRIAQDL---GLELAELVQRLFRVAS 68 Query: 66 NSAPHLVDINPSSGLLVTKQKIDRDLLCRQSPKCIISLEVM-SSSMEICVIKVEIKDLND 124 + L+++N +G+L +IDR+ LC QS +C I LEV+ +++ + VE+KD+ND Sbjct: 69 KTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKDIND 128 Query: 125 NAPSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKTRGDG 184 N P F + +L I+E+ +R PL+ A D D + TY L+ NE F L+ T G Sbjct: 129 NPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTNGKQ 188 Query: 185 SRFAELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNPVFSESTYA 244 + L+++KSLDRE + +TA DGG P GTV L ++V D NDN+P F +S Y Sbjct: 189 IKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKSEYK 248 Query: 245 VSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTVTGAL 304 VS+ EN+ T V++LNA+D DEG NG+V YS + R LF +D ++G V V G L Sbjct: 249 VSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVNGTL 307 Query: 305 DYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSESAPP 364 DYEE Y+++VQA D G + HC V V +LDTNDN P + + S++ + V E A P Sbjct: 308 DYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLS---LPVREDAQP 364 Query: 365 GYVIALVRVSDRDSGLNGRVQCRLLGNVPFRL-QEYESFSTILVDGRLDREQHDQYNLTI 423 VIAL+ VSDRDSG+NG+V C L +VPF+L ++++ ++++D LDRE Y L + Sbjct: 365 STVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVV 424 Query: 424 QARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDPDLG 483 ARDGG P L + +V + D NDN P F++P Y V V+ENN PG ++ +VSARD D Sbjct: 425 TARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQ 484 Query: 484 LNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGGLPSL 543 N VSY +V ++ D + +YVS++ SG +YAL+ +HE+ + +F+V A+D G+P L Sbjct: 485 ENALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPL 544 Query: 544 QSNATVRVIILDVNDNTPVITAPPL--INGTAEVYIPRNSGIGYLVTVVKAEDYDEGENG 601 SN T++V +LD NDN P + A G +PR+ G G++V V+A D D G N Sbjct: 545 SSNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNA 604 Query: 602 RVTYDM---TEGDRGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGKTSLSASALV 658 ++Y++ G R F + GE+ TTR E+ + L+V+ DHG+ +L+A+A V Sbjct: 605 WLSYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATV 664 Query: 659 LIYL-----SPALDAQESMGS-------VNLSLIFIIALGSIAGILFVTMI 697 L+ L +P ++ G+ V++++ IIA+ ++ +L +T++ Sbjct: 665 LVSLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLL 715 >gi|9256576 protocadherin alpha 11 isoform 1 precursor [Homo sapiens] Length = 949 Score = 483 bits (1243), Expect = e-136 Identities = 274/711 (38%), Positives = 413/711 (58%), Gaps = 28/711 (3%) Query: 6 LPVLLLLAILWTQAAALINLKYSVEEEQRAGTVIANVAKDAREAGFALDPRQASAFRVVS 65 L + LLL W + L YSV EE + GT + +A+D G L FRV S Sbjct: 14 LQLWLLLLEFWEVGSG--QLHYSVSEEAKHGTFVGRIAQDL---GLELAELVQRLFRVAS 68 Query: 66 NSAPHLVDINPSSGLLVTKQKIDRDLLCRQSPKCIISLEVM-SSSMEICVIKVEIKDLND 124 + L+++N +G+L +IDR+ LC QS +C I LEV+ +++ + VE+KD+ND Sbjct: 69 KTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKDIND 128 Query: 125 NAPSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKTRGDG 184 N P F + +L I+E+ +R PL+ A D D + TY L+ NE F L+ T G Sbjct: 129 NPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTNGKQ 188 Query: 185 SRFAELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNPVFSESTYA 244 + L+++KSLDRE + +TA DGG P GTV L ++V D NDN+P F +S Y Sbjct: 189 IKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKSEYK 248 Query: 245 VSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTVTGAL 304 VS+ EN+ T V++LNA+D DEG NG+V YS + R LF +D ++G V V G L Sbjct: 249 VSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVNGTL 307 Query: 305 DYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSESAPP 364 DYEE Y+++VQA D G + HC V V +LDTNDN P + + S++ + V E A P Sbjct: 308 DYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLS---LPVREDAQP 364 Query: 365 GYVIALVRVSDRDSGLNGRVQCRLLGNVPFRL-QEYESFSTILVDGRLDREQHDQYNLTI 423 VIAL+ VSDRDSG+NG+V C L +VPF+L ++++ ++++D LDRE Y L + Sbjct: 365 STVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVV 424 Query: 424 QARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDPDLG 483 ARDGG P L + +V + D NDN P F++P Y V V+ENN PG ++ +VSARD D Sbjct: 425 TARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQ 484 Query: 484 LNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGGLPSL 543 N VSY +V ++ D + +YVS++ SG +YAL+ +HE+ + +F+V A+D G+P L Sbjct: 485 ENALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPL 544 Query: 544 QSNATVRVIILDVNDNTPVITAPPL--INGTAEVYIPRNSGIGYLVTVVKAEDYDEGENG 601 SN T++V +LD NDN P + A G +PR+ G G++V V+A D D G N Sbjct: 545 SSNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNA 604 Query: 602 RVTYDM---TEGDRGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGKTSLSASALV 658 ++Y++ G R F + GE+ TTR E+ + L+V+ DHG+ +L+A+A V Sbjct: 605 WLSYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATV 664 Query: 659 LIYL-----SPALDAQESMGS-------VNLSLIFIIALGSIAGILFVTMI 697 L+ L +P ++ G+ V++++ IIA+ ++ +L +T++ Sbjct: 665 LVSLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLL 715 >gi|14165397 protocadherin alpha 13 isoform 2 precursor [Homo sapiens] Length = 807 Score = 483 bits (1243), Expect = e-136 Identities = 276/716 (38%), Positives = 418/716 (58%), Gaps = 26/716 (3%) Query: 8 VLLLLAILWTQAAALINLKYSVEEEQRAGTVIANVAKDAREAGFALDPRQASAFRVVSNS 67 +LL L IL L YSV EE + GT + +A+D L PR FRV S Sbjct: 14 LLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPR---LFRVASKR 70 Query: 68 APHLVDINPSSGLLVTKQKIDRDLLCRQSPKCIISLEVM-SSSMEICVIKVEIKDLNDNA 126 L+++N +G+L +IDR+ LC +S +C I LEV+ +++ ++V+++D+NDN Sbjct: 71 HGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVRDINDNP 130 Query: 127 PSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKTRGDGSR 186 P FP ++ + I+E+ P TR PLD A D D G TY L PN+ F L+ + + Sbjct: 131 PIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQNSLEQMS 190 Query: 187 FAELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNPVFSESTYAVS 246 LV+ K+LDRE +S +TA DGG P GTV L I + D NDN P F +S Y V+ Sbjct: 191 SLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQSVYKVT 250 Query: 247 VPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTVTGALDY 306 V EN+ T VI+LNA+DPD+GTNG +VYSF V F I+P++G + G LD+ Sbjct: 251 VLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKGKLDF 310 Query: 307 EEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSESAPPGY 366 EE +YE+ V+A D G + HC + V VLD NDN P + + S++ + + E P Sbjct: 311 EEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLS---LPIREDTQPSA 367 Query: 367 VIALVRVSDRDSGLNGRVQCRLLGNVPFRL-QEYESFSTILVDGRLDREQHDQYNLTIQA 425 +IAL+ VSDRDSG NG+V C L +VPF+L Y+++ ++++D LDRE Y L + A Sbjct: 368 IIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTA 427 Query: 426 RDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDPDLGLN 485 RDGG P L + S +V + D NDN P F++P Y V V+ENN PG ++ +VSA+D D N Sbjct: 428 RDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADAQEN 487 Query: 486 GSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGGLPSLQS 545 VSY +V +V + + +YVS++ SG +YAL+ +HE+ + +F+V A+D G+P L S Sbjct: 488 ALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVPPLGS 547 Query: 546 NATVRVIILDVNDNTPVITAPPL--INGTAEVYIPRNSGIGYLVTVVKAEDYDEGENGRV 603 N T++V +LD NDN P + P GT +PR+ G G++V V+A D D G N + Sbjct: 548 NVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGYNAWL 607 Query: 604 TYDM---TEGDRGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGKTSLSASALVLI 660 +Y++ G R F + GE+ TTR E + L+V+ DHG+ +L+A+A VL+ Sbjct: 608 SYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATATVLL 667 Query: 661 YL-----SPALDAQESMGS-------VNLSLIFIIALGSIAGILFVT-MIFVAIKC 703 L +P ++ S G+ V++++ IIA+ +++ +L +T +++ A++C Sbjct: 668 SLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRC 723 >gi|9256580 protocadherin alpha 13 isoform 1 precursor [Homo sapiens] Length = 950 Score = 483 bits (1243), Expect = e-136 Identities = 276/716 (38%), Positives = 418/716 (58%), Gaps = 26/716 (3%) Query: 8 VLLLLAILWTQAAALINLKYSVEEEQRAGTVIANVAKDAREAGFALDPRQASAFRVVSNS 67 +LL L IL L YSV EE + GT + +A+D L PR FRV S Sbjct: 14 LLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPR---LFRVASKR 70 Query: 68 APHLVDINPSSGLLVTKQKIDRDLLCRQSPKCIISLEVM-SSSMEICVIKVEIKDLNDNA 126 L+++N +G+L +IDR+ LC +S +C I LEV+ +++ ++V+++D+NDN Sbjct: 71 HGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVRDINDNP 130 Query: 127 PSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKTRGDGSR 186 P FP ++ + I+E+ P TR PLD A D D G TY L PN+ F L+ + + Sbjct: 131 PIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQNSLEQMS 190 Query: 187 FAELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNPVFSESTYAVS 246 LV+ K+LDRE +S +TA DGG P GTV L I + D NDN P F +S Y V+ Sbjct: 191 SLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQSVYKVT 250 Query: 247 VPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTVTGALDY 306 V EN+ T VI+LNA+DPD+GTNG +VYSF V F I+P++G + G LD+ Sbjct: 251 VLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKGKLDF 310 Query: 307 EEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSESAPPGY 366 EE +YE+ V+A D G + HC + V VLD NDN P + + S++ + + E P Sbjct: 311 EEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLS---LPIREDTQPSA 367 Query: 367 VIALVRVSDRDSGLNGRVQCRLLGNVPFRL-QEYESFSTILVDGRLDREQHDQYNLTIQA 425 +IAL+ VSDRDSG NG+V C L +VPF+L Y+++ ++++D LDRE Y L + A Sbjct: 368 IIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTA 427 Query: 426 RDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDPDLGLN 485 RDGG P L + S +V + D NDN P F++P Y V V+ENN PG ++ +VSA+D D N Sbjct: 428 RDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADAQEN 487 Query: 486 GSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGGLPSLQS 545 VSY +V +V + + +YVS++ SG +YAL+ +HE+ + +F+V A+D G+P L S Sbjct: 488 ALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVPPLGS 547 Query: 546 NATVRVIILDVNDNTPVITAPPL--INGTAEVYIPRNSGIGYLVTVVKAEDYDEGENGRV 603 N T++V +LD NDN P + P GT +PR+ G G++V V+A D D G N + Sbjct: 548 NVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGYNAWL 607 Query: 604 TYDM---TEGDRGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGKTSLSASALVLI 660 +Y++ G R F + GE+ TTR E + L+V+ DHG+ +L+A+A VL+ Sbjct: 608 SYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATATVLL 667 Query: 661 YL-----SPALDAQESMGS-------VNLSLIFIIALGSIAGILFVT-MIFVAIKC 703 L +P ++ S G+ V++++ IIA+ +++ +L +T +++ A++C Sbjct: 668 SLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRC 723 >gi|14277685 protocadherin gamma subfamily C, 5 isoform 2 precursor [Homo sapiens] Length = 878 Score = 481 bits (1238), Expect = e-135 Identities = 271/699 (38%), Positives = 399/699 (57%), Gaps = 21/699 (3%) Query: 25 LKYSVEEEQRAGTVIANVAKDAREAGFALDPRQASAFRVVSNSAPHLVDINPSSGLLVTK 84 L+YSV EE GT++ NVA+D G + + ++ S ++ SG L Sbjct: 31 LRYSVVEESEPGTLVGNVAQDL---GLKMTDLLSRRLQLGSEENGRYFSLSLMSGALAVN 87 Query: 85 QKIDRDLLCRQSPKCIISLEVMSSS-MEICVIKVEIKDLNDNAPSFPAAQIELEISEAAS 143 QKIDR+ LC S C++ ++V++ +E+ ++VEI DLNDN+PSF + E+ ISE+A+ Sbjct: 88 QKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPSFATPEREMRISESAA 147 Query: 144 PGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKTRGDGSRFAELVVEKSLDRETQSH 203 G R PLDSA DPD G+ V Y L+PN F L +KT DG F ELV+E+ LDRE Q+ Sbjct: 148 SGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELVLEQQLDREAQAR 207 Query: 204 YSFRITALDGGDPPRLGTVGLSIKVTDSNDNNPVFSESTYAVSVPENSPPNTPVIRLNAS 263 + +TA+DGG P R GT +S+ V D NDN P F S V +PEN+P T ++RLNA+ Sbjct: 208 HQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIPENAPIGTLLLRLNAT 267 Query: 264 DPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTVTGALDYEEGHVYELDVQAKDLGP 323 DPDEGTNGQ+ YSF + ++ R LF +DP SG + V G +D+EE YE+ +A+D G Sbjct: 268 DPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEESRFYEIHARARDQGQ 327 Query: 324 NSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSESAPPGYVIALVRVSDRDSGLNGR 383 ++ HC + V V D NDN P + L S+ + V ES P G V+ L V DRDSG NG Sbjct: 328 PAMEGHCVIQVDVGDVNDNAPEVLLASLAN---PVLESTPVGTVVGLFNVRDRDSGRNGE 384 Query: 384 VQCRLLGNVPFRLQEYESFSTILVDGRLDREQHDQYNLTIQARDGGVPMLQSAKSFTVLI 443 V + ++PF+++ E+ ++L LDRE Y + + A D G P L + + I Sbjct: 385 VSLDISPDLPFQIKPSENHYSLLTSQPLDREATSHYIIELLASDAGSPSLHKHLTIRLNI 444 Query: 444 TDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDPDLGLNGSVSYQIVPSQVRDMPVF 503 +D NDN P F++ Y + EN PG+ L +V+A DPD G N ++Y IV +QV+ P Sbjct: 445 SDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYSIVGNQVQGAPAS 504 Query: 504 TYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGGLPSLQSNATVRVIILDVNDNTPVI 563 ++V +NP G I+A R+F++E + + V +D G P L +N ++ V +LD NDN P + Sbjct: 505 SFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHVFVLDENDNAPAV 564 Query: 564 TAP-PLINGTAEVYIPRNSGIGYLVTVVKAEDYDEGENGRVTYDMTEGDR--GFFEIDQV 620 P P +A +PR++ G LVT V A D D G N ++Y + G F + Sbjct: 565 LHPRPDWEHSAPQRLPRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQSTAPGLFLVSTH 624 Query: 621 NGEVRTTRTFGESSKSSYELIVVAHDHGKTSLSASALVLIYLSPALDAQESMGS------ 674 GEVRT R E + +++V+ D+G SLS++A VL+ L D +E S Sbjct: 625 TGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDE-DPEEMPKSSDFLIH 683 Query: 675 ----VNLSLIFIIALGSIAGILFVTMIFVAIKCKRDNKE 709 +L+L I+AL +++ + VT F++ KC + N + Sbjct: 684 PPERSDLTLYLIVALATVSLLSLVTFTFLSAKCLQGNAD 722 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.314 0.132 0.377 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 42,352,694 Number of Sequences: 37866 Number of extensions: 1963957 Number of successful extensions: 11799 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 189 Number of HSP's successfully gapped in prelim test: 20 Number of HSP's that attempted gapping in prelim test: 3779 Number of HSP's gapped (non-prelim): 760 length of query: 1100 length of database: 18,247,518 effective HSP length: 113 effective length of query: 987 effective length of database: 13,968,660 effective search space: 13787067420 effective search space used: 13787067420 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.