BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|157388908 hypothetical protein LOC54954 [Homo sapiens] (1096 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|157388908 hypothetical protein LOC54954 [Homo sapiens] 2266 0.0 gi|39652628 oxidative stress-associated Src activator [Homo sapi... 1084 0.0 gi|24308334 family with sequence similarity 120B [Homo sapiens] 115 2e-25 gi|61966923 forkhead box B2 [Homo sapiens] 53 2e-06 gi|8923842 forkhead box J2 [Homo sapiens] 47 8e-05 gi|4885237 forkhead box C2 [Homo sapiens] 47 1e-04 gi|239757043 PREDICTED: functional smad suppressing element 18 [... 47 1e-04 gi|239751555 PREDICTED: functional smad suppressing element 18 [... 47 1e-04 gi|239746067 PREDICTED: functional smad suppressing element 18 [... 47 1e-04 gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap... 46 2e-04 gi|31657109 zinc finger protein 282 [Homo sapiens] 45 3e-04 gi|21735419 zinc finger, CCHC domain containing 14 [Homo sapiens] 45 3e-04 gi|51702521 POU domain, class 3, transcription factor 2 [Homo sa... 44 8e-04 gi|155030236 ribonuclease III, nuclear isoform 2 [Homo sapiens] 44 8e-04 gi|155030234 ribonuclease III, nuclear isoform 1 [Homo sapiens] 44 8e-04 gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens] 44 8e-04 gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 44 8e-04 gi|124107614 PR domain containing 13 [Homo sapiens] 43 0.002 gi|12751477 forkhead box L2 [Homo sapiens] 42 0.002 gi|47132620 keratin 2 [Homo sapiens] 42 0.003 gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] 41 0.005 gi|32307177 forkhead box G1 [Homo sapiens] 41 0.005 gi|66730481 neuregulin 3 [Homo sapiens] 41 0.007 gi|22027622 TNF receptor-associated factor 4 [Homo sapiens] 41 0.007 gi|161169015 neuron navigator 2 isoform 3 [Homo sapiens] 41 0.007 gi|161169013 neuron navigator 2 isoform 1 [Homo sapiens] 41 0.007 gi|38044282 neuron navigator 2 isoform 2 [Homo sapiens] 41 0.007 gi|189027090 cytoplasmic polyadenylation element binding protein... 41 0.007 gi|169636435 caudal type homeobox 2 [Homo sapiens] 40 0.009 gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens] 40 0.009 >gi|157388908 hypothetical protein LOC54954 [Homo sapiens] Length = 1096 Score = 2266 bits (5871), Expect = 0.0 Identities = 1096/1096 (100%), Positives = 1096/1096 (100%) Query: 1 MGVQGFQEFLEKRCPGAVVPVDLLKLARTVSRQQQQQHLHRQLPPTAALAPGAPRAARGS 60 MGVQGFQEFLEKRCPGAVVPVDLLKLARTVSRQQQQQHLHRQLPPTAALAPGAPRAARGS Sbjct: 1 MGVQGFQEFLEKRCPGAVVPVDLLKLARTVSRQQQQQHLHRQLPPTAALAPGAPRAARGS 60 Query: 61 VPLQPPLPPAALGAYSGGAGPIRHHHPAHHFHHHGQAQPGLHPPLPPPPPPQLPGARVLV 120 VPLQPPLPPAALGAYSGGAGPIRHHHPAHHFHHHGQAQPGLHPPLPPPPPPQLPGARVLV Sbjct: 61 VPLQPPLPPAALGAYSGGAGPIRHHHPAHHFHHHGQAQPGLHPPLPPPPPPQLPGARVLV 120 Query: 121 DAGSALPRLYGGYQTDWVCGGQWNAMLGYLSALCQACAYPGGDGLELVVMFPGGLGKDRL 180 DAGSALPRLYGGYQTDWVCGGQWNAMLGYLSALCQACAYPGGDGLELVVMFPGGLGKDRL Sbjct: 121 DAGSALPRLYGGYQTDWVCGGQWNAMLGYLSALCQACAYPGGDGLELVVMFPGGLGKDRL 180 Query: 181 AEWGRRCQAERQTAQLIVGHVGNKGTPPPRAWFLPPACLSHCVRLALIRFRVKVFQSLED 240 AEWGRRCQAERQTAQLIVGHVGNKGTPPPRAWFLPPACLSHCVRLALIRFRVKVFQSLED Sbjct: 181 AEWGRRCQAERQTAQLIVGHVGNKGTPPPRAWFLPPACLSHCVRLALIRFRVKVFQSLED 240 Query: 241 HHLEVVAFFRENGFHGLLAHDSEYALYNIPSYYSSHALKLSWNGKNLTTNQFLMQEVAKQ 300 HHLEVVAFFRENGFHGLLAHDSEYALYNIPSYYSSHALKLSWNGKNLTTNQFLMQEVAKQ Sbjct: 241 HHLEVVAFFRENGFHGLLAHDSEYALYNIPSYYSSHALKLSWNGKNLTTNQFLMQEVAKQ 300 Query: 301 LGLKRMNFPIFAALLGNHILPDEDLAAFHWSLLGPEHPLASLKVRAHQLVLPPCDVVIKA 360 LGLKRMNFPIFAALLGNHILPDEDLAAFHWSLLGPEHPLASLKVRAHQLVLPPCDVVIKA Sbjct: 301 LGLKRMNFPIFAALLGNHILPDEDLAAFHWSLLGPEHPLASLKVRAHQLVLPPCDVVIKA 360 Query: 361 VSEYVSSIKDPSNLDVVGKDVFKQSQSRTEDKIERFKKAVEYYSVTTKLSSLPVGPSFLG 420 VSEYVSSIKDPSNLDVVGKDVFKQSQSRTEDKIERFKKAVEYYSVTTKLSSLPVGPSFLG Sbjct: 361 VSEYVSSIKDPSNLDVVGKDVFKQSQSRTEDKIERFKKAVEYYSVTTKLSSLPVGPSFLG 420 Query: 421 FRNNRLGNPPLPRNQVGTISAGKPMFSHQVPQKVKYPPPFPVGPNSSLLFSSHALGESHA 480 FRNNRLGNPPLPRNQVGTISAGKPMFSHQVPQKVKYPPPFPVGPNSSLLFSSHALGESHA Sbjct: 421 FRNNRLGNPPLPRNQVGTISAGKPMFSHQVPQKVKYPPPFPVGPNSSLLFSSHALGESHA 480 Query: 481 FSEDPMLQNSPFANWAVSYDSSASQFPNYLPSKASPPLGPDSSHSSSSDGDEPNGASSDH 540 FSEDPMLQNSPFANWAVSYDSSASQFPNYLPSKASPPLGPDSSHSSSSDGDEPNGASSDH Sbjct: 481 FSEDPMLQNSPFANWAVSYDSSASQFPNYLPSKASPPLGPDSSHSSSSDGDEPNGASSDH 540 Query: 541 ITEAFHHQPEWGNPNRDRGSWAQPVDTGVSEASLGDGEPHIPSLLSMSTRNHMDITIPPL 600 ITEAFHHQPEWGNPNRDRGSWAQPVDTGVSEASLGDGEPHIPSLLSMSTRNHMDITIPPL Sbjct: 541 ITEAFHHQPEWGNPNRDRGSWAQPVDTGVSEASLGDGEPHIPSLLSMSTRNHMDITIPPL 600 Query: 601 PPVAPEVLRVAEHRHRRGLMYPYIYHVLTKGEIKIPVCIEDECNMELPPAALLFRSARQY 660 PPVAPEVLRVAEHRHRRGLMYPYIYHVLTKGEIKIPVCIEDECNMELPPAALLFRSARQY Sbjct: 601 PPVAPEVLRVAEHRHRRGLMYPYIYHVLTKGEIKIPVCIEDECNMELPPAALLFRSARQY 660 Query: 661 VYGVLFSLAETQRKMERLAMRRRLPVEVPSVILKEWSAYKGKSPQTPELVSALTFREWTC 720 VYGVLFSLAETQRKMERLAMRRRLPVEVPSVILKEWSAYKGKSPQTPELVSALTFREWTC Sbjct: 661 VYGVLFSLAETQRKMERLAMRRRLPVEVPSVILKEWSAYKGKSPQTPELVSALTFREWTC 720 Query: 721 PNLKKLWLGKAVEDKNRRMRAFLACMKSDTPSMLNPANVPTHLLLMCCVLRYMVQWPGGR 780 PNLKKLWLGKAVEDKNRRMRAFLACMKSDTPSMLNPANVPTHLLLMCCVLRYMVQWPGGR Sbjct: 721 PNLKKLWLGKAVEDKNRRMRAFLACMKSDTPSMLNPANVPTHLLLMCCVLRYMVQWPGGR 780 Query: 781 ILHRHELDTFLAQAVSTQLYEPDRLQELKIEKLDARGIQLAALFMSGVDTALFANDACGQ 840 ILHRHELDTFLAQAVSTQLYEPDRLQELKIEKLDARGIQLAALFMSGVDTALFANDACGQ Sbjct: 781 ILHRHELDTFLAQAVSTQLYEPDRLQELKIEKLDARGIQLAALFMSGVDTALFANDACGQ 840 Query: 841 PVPWEHCCPWIYFDGKLFQSKLIKAGRERVSLVELCDGQADLATKVEKMRQSILEGVNMN 900 PVPWEHCCPWIYFDGKLFQSKLIKAGRERVSLVELCDGQADLATKVEKMRQSILEGVNMN Sbjct: 841 PVPWEHCCPWIYFDGKLFQSKLIKAGRERVSLVELCDGQADLATKVEKMRQSILEGVNMN 900 Query: 901 HPPPSALLPSPTFVPPMVPSLYPVSLYSRAMGSMPLPPQGRSRGFAGLHPIPPQGGKLEI 960 HPPPSALLPSPTFVPPMVPSLYPVSLYSRAMGSMPLPPQGRSRGFAGLHPIPPQGGKLEI Sbjct: 901 HPPPSALLPSPTFVPPMVPSLYPVSLYSRAMGSMPLPPQGRSRGFAGLHPIPPQGGKLEI 960 Query: 961 AGMVVGQWAGSRSSRGRGSFGMQVVSVGGPGKGHGKEQTGRGSKGHKKGNKQGSSDGVSK 1020 AGMVVGQWAGSRSSRGRGSFGMQVVSVGGPGKGHGKEQTGRGSKGHKKGNKQGSSDGVSK Sbjct: 961 AGMVVGQWAGSRSSRGRGSFGMQVVSVGGPGKGHGKEQTGRGSKGHKKGNKQGSSDGVSK 1020 Query: 1021 SLELHQGRSRSQVNGNSGALIKEEKSDHRLPAPSQCALSRDSNECNNGNRYLPMNNREKN 1080 SLELHQGRSRSQVNGNSGALIKEEKSDHRLPAPSQCALSRDSNECNNGNRYLPMNNREKN Sbjct: 1021 SLELHQGRSRSQVNGNSGALIKEEKSDHRLPAPSQCALSRDSNECNNGNRYLPMNNREKN 1080 Query: 1081 HLQEQKLETVAQRKED 1096 HLQEQKLETVAQRKED Sbjct: 1081 HLQEQKLETVAQRKED 1096 >gi|39652628 oxidative stress-associated Src activator [Homo sapiens] Length = 1118 Score = 1084 bits (2803), Expect = 0.0 Identities = 609/1098 (55%), Positives = 731/1098 (66%), Gaps = 129/1098 (11%) Query: 110 PPQLPGARVLVDAGSALPRLYGGYQTDWVCGGQWNAMLGYLSALCQACAYPGGDGLELVV 169 PPQ P R+LVDA + L RLYGG+ TDWV GGQWN MLGYL+AL +AC G +EL V Sbjct: 39 PPQTP-LRLLVDADNCLHRLYGGFYTDWVSGGQWNHMLGYLAALAKACF---GGNIELFV 94 Query: 170 MFPGGLGKDRLAEWGRRCQAERQTAQLIVGHVGNKGTPPPRAWFLPPACLSHCVRLALIR 229 F G L K RL EW +R ERQTAQ IV HV NKGTPPP+ WFLPP C++HC+RLALIR Sbjct: 95 FFNGALEKARLHEWVKRQGNERQTAQQIVSHVQNKGTPPPKVWFLPPVCMAHCIRLALIR 154 Query: 230 FRVKVFQSLEDHHLEVVAFFRENGFHGLLAHDSEYALYNIPSYYSSHALKLSWNGKNLTT 289 F VKV QS+EDHH EV+ F RENGFHGL+A+DS+YAL NIP Y+S+HALKLS NGK+LTT Sbjct: 155 FHVKVAQSIEDHHQEVIGFCRENGFHGLVAYDSDYALCNIPYYFSAHALKLSRNGKSLTT 214 Query: 290 NQFLMQEVAKQLGLKRMNFPIFAALLGNHILPDEDLAAFHWSLLGPEHPLASLKVRAHQL 349 +Q+LM EVAKQL L FPIFAALLGNHILPDEDLA+FHWSLLGPEHPLASLKVRAHQL Sbjct: 215 SQYLMHEVAKQLDLNPNRFPIFAALLGNHILPDEDLASFHWSLLGPEHPLASLKVRAHQL 274 Query: 350 VLPPCDVVIKAVSEYVSSIKDPSNLDVVGKDVFKQSQSRTEDKIERFKKAVEYYSVTTKL 409 VLPPCDVVIKAV++YV +I+D S+LD + KDVF+ SQSRT+DK+ RFK+A+ YYS T+K Sbjct: 275 VLPPCDVVIKAVADYVRNIQDTSDLDAIAKDVFQHSQSRTDDKVIRFKRAIGYYSATSKP 334 Query: 410 SSLPVGPSFLGFRNNRLGNP--------PLPRNQVGTISAGKPMFSHQVPQKVKYPP--P 459 S P +L R G P P N T KP+ + QVP P P Sbjct: 335 MSFHP-PHYLAARPGPFGMPGMVPPHVPPQMLNIPQTSLQAKPV-APQVPSPGGAPGQGP 392 Query: 460 FPVGPNS----SLLFSSHALGESHAFSEDPML-QNSPFANWAVSYDSSASQFPNYLPSKA 514 +P + +L S L E +++S P +++P + + + S PN++ S Sbjct: 393 YPYSLSEPAPLTLDTSGKNLTEQNSYSNIPHEGKHTPLYERSSPINPAQSGSPNHVDSAY 452 Query: 515 SPPLGPDSSHSSSSDGDEPNGASSDHIT--------EAFHHQPEW----GNPNRDRGSWA 562 P SS SSSSD DE +G +++HI+ H +P+ G+ + GS Sbjct: 453 FP----GSSTSSSSDNDEGSGGATNHISGNKIGWEKTGSHSEPQARGDPGDQTKAEGSST 508 Query: 563 QPVDTGVSE---ASLGDGEPHIPSLLSMSTRNHMDITIPPLPPVAPEVLRVAEHRHRRGL 619 + ++E + +G +P IP LLSM TRNHMDIT PPLPPVAPEVLRVAEHRH++GL Sbjct: 509 ASSGSQLAEGKGSQMGTVQP-IPCLLSMPTRNHMDITTPPLPPVAPEVLRVAEHRHKKGL 567 Query: 620 MYPYIYHVLTKGEIKIPVCIEDECNMELPPAALLFRSARQYVYGVLFSLAETQRKMERLA 679 MYPYI+HVLTKGEIKI V IEDE N +LPPAALL+R RQYVYGVLFSLAE+++K ERLA Sbjct: 568 MYPYIFHVLTKGEIKIAVSIEDEANKDLPPAALLYRPVRQYVYGVLFSLAESRKKTERLA 627 Query: 680 MRR-RLPVEVPSVILKEWSAYKGKSPQTPELVSALTFREWTCPNLKKLWLGKAVEDKNRR 738 R+ RLP E VI+KEW+AYKGKSPQTPELV AL FREWTCPNLK+LWLGKAVEDKNRR Sbjct: 628 FRKNRLPPEFSPVIIKEWAAYKGKSPQTPELVEALAFREWTCPNLKRLWLGKAVEDKNRR 687 Query: 739 MRAFLACMKSDTPSMLNPANVPTHLLLMCCVLRYMVQWPGGRILHRHELDTFLAQAVSTQ 798 MRAFLACM+SDTP+MLNPANVPTHL+++CCVLRYMVQWPG RIL R ELD FLAQA+S + Sbjct: 688 MRAFLACMRSDTPAMLNPANVPTHLMVLCCVLRYMVQWPGARILRRQELDAFLAQALSPK 747 Query: 799 LYEPDRLQELKIEKLDARGIQLAALFMSGVDTALFANDACGQPVPWEHCCPWIYFDGKLF 858 LYEPD+LQELKIE LD RGIQL+ALFMSGVD ALFANDACGQP+PWEHCCPW+YFDGKLF Sbjct: 748 LYEPDQLQELKIENLDPRGIQLSALFMSGVDMALFANDACGQPIPWEHCCPWMYFDGKLF 807 Query: 859 QSKLIKAGRERVSLVELCDGQADLATKVEKMRQSILEGVNMNHPPPSALLPSPTFVPPMV 918 QSKL+KA RE+ L++LCDGQAD A KVEKMRQS+LEG++ + S LP P PP + Sbjct: 808 QSKLLKASREKTPLIDLCDGQADQAAKVEKMRQSVLEGLSFSR--QSHTLPFPP--PPAL 863 Query: 919 PSLYPVSLYSRAMGSMPLPPQGRSRGFA-------------------------------- 946 P YP S Y R G +P P QGR RGFA Sbjct: 864 P-FYPASAYPRHFGPVP-PSQGRGRGFAGVCGFGGPYGETVATGPYRAFRVAAASGHCGA 921 Query: 947 --------------GLHPIPPQGGKLEIAGMVVGQWAGSRSSR-GRGSFGMQVVSVGGPG 991 G+ PIP QGGKLEIAG VVG WAGSR R GRG F +QVVSVGGP Sbjct: 922 FSGSDSSRTSKSQGGVQPIPSQGGKLEIAGTVVGHWAGSRRGRGGRGPFPLQVVSVGGPA 981 Query: 992 KGHGK--------EQTGRGSKGHKKGNKQ-----------GSSDGVSKSLELHQGRSRSQ 1032 +G + GRG + + +G K S++ V+K L+ G S+S Sbjct: 982 RGRPRGVISTPVIRTFGRGGRYYGRGYKNQAAIQGRPPYAASAEEVAKELKSKSGESKSS 1041 Query: 1033 VNGNSGAL-----IKEEK---------SDHRLPAPSQCALSRDSNECNNGNRYLPMNNRE 1078 + G+L + EEK D R P+ S+ AL+ DS CN N +L + + Sbjct: 1042 AMSSDGSLAENGVMAEEKPAPQMNGSTGDARAPSHSESALNNDSKTCNT-NPHLNALSTD 1100 Query: 1079 KNHLQEQKLETVAQRKED 1096 +E LE KE+ Sbjct: 1101 SACRREAALEAAVLNKEE 1118 Score = 48.9 bits (115), Expect = 3e-05 Identities = 21/28 (75%), Positives = 25/28 (89%) Query: 1 MGVQGFQEFLEKRCPGAVVPVDLLKLAR 28 MGVQGFQ+++EK CP AVVPV+L KLAR Sbjct: 1 MGVQGFQDYIEKHCPSAVVPVELQKLAR 28 >gi|24308334 family with sequence similarity 120B [Homo sapiens] Length = 910 Score = 115 bits (289), Expect = 2e-25 Identities = 81/262 (30%), Positives = 123/262 (46%), Gaps = 21/262 (8%) Query: 606 EVLRVAEHRHRRGLMYPYIYHVLTKGEIKIPVCIEDECNMELPPAALLFRSARQYVYGVL 665 E+L+VA H + Y +Y++++ GEI+ +EDE + LP A ++R RQ VY +L Sbjct: 575 EILKVARTHHVQAESY-LVYNIMSSGEIECSNTLEDELDQALPSQAFIYRPIRQRVYSLL 633 Query: 666 FSLAETQRKMERLAMRRRLPVEVPSVILKEWSAYKGKSPQTPELVSALTFR-EWTCPNLK 724 + V + +KEW Y G + P+LV L P+LK Sbjct: 634 LEDCQD--------------VTSTCLAVKEWFVYPGNPLRHPDLVRPLQMTIPGGTPSLK 679 Query: 725 KLWLGKAVEDKNRRMRAFLACMK-SDTPSMLNPANVPTHLLLMCCVLRYMVQWPGGRILH 783 LWL + E + RR+ LAC S + L P L CC+L Y+ L Sbjct: 680 ILWLNQEPEIQVRRLDTLLACFNLSSSREELQAVESPFQAL--CCLLIYLFVQVDTLCLE 737 Query: 784 RHELDTFLAQAVSTQLYEPDRLQELKIEKLDARGIQLAALFMSGVDTALFANDACGQPVP 843 +L F+AQA+ Q +L L+ + ++ R +QL +L + G+ T + N ACG P Sbjct: 738 --DLHAFIAQALCLQGKSTSQLVNLQPDYINPRAVQLGSLLVRGLTTLVLVNSACGFPWK 795 Query: 844 WEHCCPWIYFDGKLFQSKLIKA 865 PW FDGKLF K +++ Sbjct: 796 TSDFMPWNVFDGKLFHQKYLQS 817 Score = 88.6 bits (218), Expect = 3e-17 Identities = 69/272 (25%), Positives = 116/272 (42%), Gaps = 22/272 (8%) Query: 93 HHGQAQPGLHPPLPPPPPPQLPGARVLVDAGSALPRLYGGYQTDWVCGGQWNAMLGYLSA 152 HH PG P ++VDA L Y W+CGGQW Y SA Sbjct: 29 HHRSKYPGCTPT-------------IVVDAMCCLRYWYT--PESWICGGQWRE---YFSA 70 Query: 153 LCQACAYPGGDGLELVVMFPGGLGKDRLAEWGRRCQAERQTAQLIVGHVGNKGTPPPRAW 212 L G++L+ F G + +D+ EW +R + I ++ + P R Sbjct: 71 LRDFVKTFTAAGIKLIFFFDGMVEQDKRDEWVKRRLKNNREISRIFHYIKSHKEQPGRNM 130 Query: 213 FLPPACLSHCVRLALIRFRVKVFQSLEDHHLEVVAFFRENGFHGLLAHDSEYALYNIPSY 272 F P+ L+ R AL + SL++ EV ++ ++ G+L D++Y +Y+ Y Sbjct: 131 FFIPSGLAVFTRFALKTLGQETLCSLQEADYEVASYGLQHNCLGILGEDTDYLIYDTCPY 190 Query: 273 YSSHALKLSWNGKNLTTNQFLMQEVAKQLGLKRMNFPIFAALLGNHILPDEDLAAFHWSL 332 +S L L ++L T +++ + LGL + P+ A LLGN I+P+ +F + Sbjct: 191 FSISELCL----ESLDTVMLCREKLCESLGLCVADLPLLACLLGNDIIPEGMFESFRYKC 246 Query: 333 LGPEHPLASLKVRAHQLVLPPCDVVIKAVSEY 364 L + + ++L D + K + Y Sbjct: 247 LSSYTSVKENFDKKGNIILAVSDHISKVLYLY 278 >gi|61966923 forkhead box B2 [Homo sapiens] Length = 432 Score = 52.8 bits (125), Expect = 2e-06 Identities = 26/48 (54%), Positives = 27/48 (56%), Gaps = 3/48 (6%) Query: 70 AALGAYSGG-AGPIRHHHPAHHFHHHGQA--QPGLHPPLPPPPPPQLP 114 +A GA GG P HHHP HH HHH A HPP PPPPPP P Sbjct: 126 SAPGAGPGGHLHPHHHHHPHHHHHHHAAAHHHHHHHPPQPPPPPPPPP 173 >gi|8923842 forkhead box J2 [Homo sapiens] Length = 574 Score = 47.4 bits (111), Expect = 8e-05 Identities = 40/113 (35%), Positives = 47/113 (41%), Gaps = 17/113 (15%) Query: 32 RQQQQQHLHRQLPPTAAL-----APG-APRAARGSVPLQPP-----LPPAA--LGAYSGG 78 +QQQQQ Q PP + AP P A G+ PL P PP GA G Sbjct: 299 QQQQQQQQPPQPPPQQSQPQQQQAPAQGPSAVGGAPPLHTPSTDGCTPPGGKQAGAEGYG 358 Query: 79 AGPIRHHHPA---HHFHHHGQAQPGLHPP-LPPPPPPQLPGARVLVDAGSALP 127 P+ HP H +H Q P HP PPPP PQ G + + G A P Sbjct: 359 PPPVMAMHPPPLQHGGYHPHQHHPHSHPAQQPPPPQPQAQGQAPINNTGFAFP 411 >gi|4885237 forkhead box C2 [Homo sapiens] Length = 501 Score = 47.0 bits (110), Expect = 1e-04 Identities = 29/74 (39%), Positives = 32/74 (43%), Gaps = 4/74 (5%) Query: 45 PTAALAPGAPRAARGSVPLQPPLPPAALGAYSGGAGPIRH--HHPAHHFHHHGQAQPGLH 102 P P A A P P P +AL +G G + HH HH HHH QA P Sbjct: 345 PAHMCVPPALDEALSDHPSGPTSPLSALNLAAGQEGALAATGHHHQHHGHHHPQAPP--P 402 Query: 103 PPLPPPPPPQLPGA 116 PP P P P PGA Sbjct: 403 PPAPQPQPTPQPGA 416 >gi|239757043 PREDICTED: functional smad suppressing element 18 [Homo sapiens] Length = 996 Score = 47.0 bits (110), Expect = 1e-04 Identities = 25/62 (40%), Positives = 27/62 (43%), Gaps = 17/62 (27%) Query: 70 AALGA-YSGGAGPIRHHHPAHHFHHHGQAQP----------------GLHPPLPPPPPPQ 112 A+ GA +S P HHHP HH HHH QP H P PPPPPP Sbjct: 642 ASAGAPHSAQTHPHHHHHPHHHHHHHHPPQPPSPLLLLPPQPDEPGSERHHPAPPPPPPP 701 Query: 113 LP 114 P Sbjct: 702 PP 703 Score = 34.7 bits (78), Expect = 0.51 Identities = 21/53 (39%), Positives = 22/53 (41%), Gaps = 7/53 (13%) Query: 70 AALGAYSGGAGPIRHHHPAHHFHHHGQAQPGLHPPLPP------PPPPQLPGA 116 A L S GA HP HH H H HPP PP PP P PG+ Sbjct: 637 AKLHGASAGAPHSAQTHPHHHHHPHHHHHHH-HPPQPPSPLLLLPPQPDEPGS 688 Score = 33.9 bits (76), Expect = 0.87 Identities = 24/65 (36%), Positives = 25/65 (38%), Gaps = 16/65 (24%) Query: 62 PLQPPLPPAALGAYSGGAGPIRHHHPAHHFHHHGQAQPGLHPPLPPPPPPQL---PGARV 118 P QPP P L G RHH P PP PPPPPP L P R Sbjct: 669 PPQPPSPLLLLPPQPDEPGSERHH-------------PAPPPPPPPPPPPPLAQHPHHRG 715 Query: 119 LVDAG 123 L+ G Sbjct: 716 LLSPG 720 Score = 30.4 bits (67), Expect = 9.6 Identities = 39/145 (26%), Positives = 53/145 (36%), Gaps = 18/145 (12%) Query: 889 MRQSILEGVNMNHPPPSALLPSPTFVPPMVPSLYPVSLYSRAMGSMPLPPQGRSRGFAGL 948 +RQ+ L+ SA P PP V + P GS P PP G + L Sbjct: 506 LRQAFLDLAEPGGAAGSAEAAPPPGQPPQVVANGP--------GSGPPPPAGGAGSRDAL 557 Query: 949 HPIPPQG-------GKLEIAGMVVGQWAGSRSSRGRGSFGMQVVSVGGPGKGHGKEQTGR 1001 PP G G A V AG+ ++ G G G +V + P G+ + G Sbjct: 558 FESPPGGSGGDCSAGSTPPADSVAAAGAGA-AAAGSGPAGSRVPAPHHPHLLEGR-KAGG 615 Query: 1002 GSKGHKKGNKQ-GSSDGVSKSLELH 1025 GS H + G D +LH Sbjct: 616 GSYHHSSAFRPVGGKDDAESLAKLH 640 >gi|239751555 PREDICTED: functional smad suppressing element 18 [Homo sapiens] Length = 1252 Score = 47.0 bits (110), Expect = 1e-04 Identities = 25/62 (40%), Positives = 27/62 (43%), Gaps = 17/62 (27%) Query: 70 AALGA-YSGGAGPIRHHHPAHHFHHHGQAQP----------------GLHPPLPPPPPPQ 112 A+ GA +S P HHHP HH HHH QP H P PPPPPP Sbjct: 642 ASAGAPHSAQTHPHHHHHPHHHHHHHHPPQPPSPLLLLPPQPDEPGSERHHPAPPPPPPP 701 Query: 113 LP 114 P Sbjct: 702 PP 703 Score = 34.7 bits (78), Expect = 0.51 Identities = 21/53 (39%), Positives = 22/53 (41%), Gaps = 7/53 (13%) Query: 70 AALGAYSGGAGPIRHHHPAHHFHHHGQAQPGLHPPLPP------PPPPQLPGA 116 A L S GA HP HH H H HPP PP PP P PG+ Sbjct: 637 AKLHGASAGAPHSAQTHPHHHHHPHHHHHHH-HPPQPPSPLLLLPPQPDEPGS 688 Score = 33.9 bits (76), Expect = 0.87 Identities = 24/65 (36%), Positives = 25/65 (38%), Gaps = 16/65 (24%) Query: 62 PLQPPLPPAALGAYSGGAGPIRHHHPAHHFHHHGQAQPGLHPPLPPPPPPQL---PGARV 118 P QPP P L G RHH P PP PPPPPP L P R Sbjct: 669 PPQPPSPLLLLPPQPDEPGSERHH-------------PAPPPPPPPPPPPPLAQHPHHRG 715 Query: 119 LVDAG 123 L+ G Sbjct: 716 LLSPG 720 Score = 30.4 bits (67), Expect = 9.6 Identities = 39/145 (26%), Positives = 53/145 (36%), Gaps = 18/145 (12%) Query: 889 MRQSILEGVNMNHPPPSALLPSPTFVPPMVPSLYPVSLYSRAMGSMPLPPQGRSRGFAGL 948 +RQ+ L+ SA P PP V + P GS P PP G + L Sbjct: 506 LRQAFLDLAEPGGAAGSAEAAPPPGQPPQVVANGP--------GSGPPPPAGGAGSRDAL 557 Query: 949 HPIPPQG-------GKLEIAGMVVGQWAGSRSSRGRGSFGMQVVSVGGPGKGHGKEQTGR 1001 PP G G A V AG+ ++ G G G +V + P G+ + G Sbjct: 558 FESPPGGSGGDCSAGSTPPADSVAAAGAGA-AAAGSGPAGSRVPAPHHPHLLEGR-KAGG 615 Query: 1002 GSKGHKKGNKQ-GSSDGVSKSLELH 1025 GS H + G D +LH Sbjct: 616 GSYHHSSAFRPVGGKDDAESLAKLH 640 >gi|239746067 PREDICTED: functional smad suppressing element 18 [Homo sapiens] Length = 1252 Score = 47.0 bits (110), Expect = 1e-04 Identities = 25/62 (40%), Positives = 27/62 (43%), Gaps = 17/62 (27%) Query: 70 AALGA-YSGGAGPIRHHHPAHHFHHHGQAQP----------------GLHPPLPPPPPPQ 112 A+ GA +S P HHHP HH HHH QP H P PPPPPP Sbjct: 642 ASAGAPHSAQTHPHHHHHPHHHHHHHHPPQPPSPLLLLPPQPDEPGSERHHPAPPPPPPP 701 Query: 113 LP 114 P Sbjct: 702 PP 703 Score = 34.7 bits (78), Expect = 0.51 Identities = 21/53 (39%), Positives = 22/53 (41%), Gaps = 7/53 (13%) Query: 70 AALGAYSGGAGPIRHHHPAHHFHHHGQAQPGLHPPLPP------PPPPQLPGA 116 A L S GA HP HH H H HPP PP PP P PG+ Sbjct: 637 AKLHGASAGAPHSAQTHPHHHHHPHHHHHHH-HPPQPPSPLLLLPPQPDEPGS 688 Score = 33.9 bits (76), Expect = 0.87 Identities = 24/65 (36%), Positives = 25/65 (38%), Gaps = 16/65 (24%) Query: 62 PLQPPLPPAALGAYSGGAGPIRHHHPAHHFHHHGQAQPGLHPPLPPPPPPQL---PGARV 118 P QPP P L G RHH P PP PPPPPP L P R Sbjct: 669 PPQPPSPLLLLPPQPDEPGSERHH-------------PAPPPPPPPPPPPPLAQHPHHRG 715 Query: 119 LVDAG 123 L+ G Sbjct: 716 LLSPG 720 Score = 30.4 bits (67), Expect = 9.6 Identities = 39/145 (26%), Positives = 53/145 (36%), Gaps = 18/145 (12%) Query: 889 MRQSILEGVNMNHPPPSALLPSPTFVPPMVPSLYPVSLYSRAMGSMPLPPQGRSRGFAGL 948 +RQ+ L+ SA P PP V + P GS P PP G + L Sbjct: 506 LRQAFLDLAEPGGAAGSAEAAPPPGQPPQVVANGP--------GSGPPPPAGGAGSRDAL 557 Query: 949 HPIPPQG-------GKLEIAGMVVGQWAGSRSSRGRGSFGMQVVSVGGPGKGHGKEQTGR 1001 PP G G A V AG+ ++ G G G +V + P G+ + G Sbjct: 558 FESPPGGSGGDCSAGSTPPADSVAAAGAGA-AAAGSGPAGSRVPAPHHPHLLEGR-KAGG 615 Query: 1002 GSKGHKKGNKQ-GSSDGVSKSLELH 1025 GS H + G D +LH Sbjct: 616 GSYHHSSAFRPVGGKDDAESLAKLH 640 >gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens] Length = 2161 Score = 46.2 bits (108), Expect = 2e-04 Identities = 24/68 (35%), Positives = 28/68 (41%), Gaps = 6/68 (8%) Query: 52 GAPRAARGSVPLQPPLPP-AALGA-----YSGGAGPIRHHHPAHHFHHHGQAQPGLHPPL 105 G P A P PP +G+ Y G P HHHP HH HHH H Sbjct: 959 GGPLPASSPASFDGPSPPDTRVGSREKSLYHSGPLPPAHHHPPHHHHHHAPPPQPHHHHA 1018 Query: 106 PPPPPPQL 113 PP PP++ Sbjct: 1019 HPPHPPEM 1026 >gi|31657109 zinc finger protein 282 [Homo sapiens] Length = 671 Score = 45.4 bits (106), Expect = 3e-04 Identities = 56/207 (27%), Positives = 75/207 (36%), Gaps = 29/207 (14%) Query: 899 MNHPPPSALLPSPTFVPPMVPSLY----PVSLYSRAMGSMPLPPQGRSRGFAGLHPIPPQ 954 + +PPP+ P P PP P L P SL A+ P P R G +P + Sbjct: 400 VKNPPPAPPQPQPQPQPPQ-PQLQSQPQPQSLPPIAVAENPGGPPSRGLLDDGFQVLPGE 458 Query: 955 GGKLEIAGMVVGQWAGSRSSRGRGSFGMQVVSVGGPGKGHGKEQTGRGSKGHKKGNKQGS 1014 G E G RS+ G G G G G G + G G+ G G Sbjct: 459 RGSGEAPP------GGDRSTGGGGGDG---------GGGGGGAEAGTGAGG---GCGSCC 500 Query: 1015 SDGVSKSLELHQGRSRSQVNGNSGALIKEEKS------DHRLPAPSQCALSRDSNECNNG 1068 G+ +SL LH RS+ G KS H P +CA S C++G Sbjct: 501 PGGLRRSLLLHGARSKPYSCPECGKSFGVRKSLIIHHRSHTKERPYECAECEKSFNCHSG 560 Query: 1069 NRYLPMNNREKNHLQEQKLETVAQRKE 1095 M +R + + + E RKE Sbjct: 561 LIRHQMTHRGERPYKCSECEKTYSRKE 587 >gi|21735419 zinc finger, CCHC domain containing 14 [Homo sapiens] Length = 949 Score = 45.4 bits (106), Expect = 3e-04 Identities = 27/67 (40%), Positives = 32/67 (47%), Gaps = 7/67 (10%) Query: 48 ALAPGAPRAARGSVPLQPPLPPAALGAYSGGAGP---IRHHHPAHHFHHHGQAQPGLHPP 104 A P P A S P +P ++ + SGG G I +P HH HHH Q P PP Sbjct: 721 ATLPSCP--APSSSPALSSVPESSFYSSSGGGGSTGNIPASNPNHHHHHHHQQPPA--PP 776 Query: 105 LPPPPPP 111 P PPPP Sbjct: 777 QPAPPPP 783 >gi|51702521 POU domain, class 3, transcription factor 2 [Homo sapiens] Length = 443 Score = 43.9 bits (102), Expect = 8e-04 Identities = 34/110 (30%), Positives = 41/110 (37%), Gaps = 27/110 (24%) Query: 32 RQQQQQHLHRQLPPTAAL-------APGAPRAARGSVPLQPPLPPAALGAY--------- 75 +QQQQQ +Q PP PGA R+A + L P + + G Sbjct: 139 QQQQQQQQQQQRPPHLVHHAANHHPGPGAWRSAAAAAHLPPSMGASNGGLLYSQPSFTVN 198 Query: 76 ----SGGAGPIRHHH-------PAHHFHHHGQAQPGLHPPLPPPPPPQLP 114 +GG HHH HH HH H PPPPPPQ P Sbjct: 199 GMLGAGGQPAGLHHHGLRDAHDEPHHADHHPHPHSHPHQQPPPPPPPQGP 248 >gi|155030236 ribonuclease III, nuclear isoform 2 [Homo sapiens] Length = 1337 Score = 43.9 bits (102), Expect = 8e-04 Identities = 35/104 (33%), Positives = 41/104 (39%), Gaps = 22/104 (21%) Query: 32 RQQQQQHLHRQLPPTAAL--APGAPRAARGS-------------VPLQPPLPPAALGAYS 76 R Q + LH Q PP P AP + VP PP+PP+A G Sbjct: 35 RPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLP 94 Query: 77 GGAGPIRHHHPAHHFHHHGQAQPGLHPPLPPPPP----PQLPGA 116 PIR P H H P PP+PPP P P +PGA Sbjct: 95 --PCPIRPPFPNHQMRHPFPVPP-CFPPMPPPMPCPNNPPVPGA 135 >gi|155030234 ribonuclease III, nuclear isoform 1 [Homo sapiens] Length = 1374 Score = 43.9 bits (102), Expect = 8e-04 Identities = 35/104 (33%), Positives = 41/104 (39%), Gaps = 22/104 (21%) Query: 32 RQQQQQHLHRQLPPTAAL--APGAPRAARGS-------------VPLQPPLPPAALGAYS 76 R Q + LH Q PP P AP + VP PP+PP+A G Sbjct: 35 RPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLP 94 Query: 77 GGAGPIRHHHPAHHFHHHGQAQPGLHPPLPPPPP----PQLPGA 116 PIR P H H P PP+PPP P P +PGA Sbjct: 95 --PCPIRPPFPNHQMRHPFPVPP-CFPPMPPPMPCPNNPPVPGA 135 >gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens] Length = 1488 Score = 43.9 bits (102), Expect = 8e-04 Identities = 30/93 (32%), Positives = 34/93 (36%), Gaps = 23/93 (24%) Query: 58 RGSVPLQPPLPPAALGAYSGGAGPIRHHHPAHHFHHHGQAQPGL---------------- 101 RG P Q P PP + S + HHH HH HHHG + GL Sbjct: 1213 RGKGPFQMPPPPTGQASASSSSASSTHHH--HHHHHHGHSHGGLGVLPDGQSKLQALHAQ 1270 Query: 102 --HPPLPPPPP---PQLPGARVLVDAGSALPRL 129 P P PPP PQ P LP+L Sbjct: 1271 YCQGPGPAPPPYLPPQQPSLPPPPQQPPPLPQL 1303 Score = 30.8 bits (68), Expect = 7.3 Identities = 19/52 (36%), Positives = 21/52 (40%), Gaps = 7/52 (13%) Query: 65 PPLPPAALGAYSGGAGP-----IRHHHPAHHFHHHGQAQPGLHPPLPPPPPP 111 P + PAA A G+ P HHP H P HP PP PPP Sbjct: 1394 PQMMPAAGAAGGPGSRPPGGSYSHPHHPQSPLSPHSPIPP--HPSYPPLPPP 1443 >gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] Length = 538 Score = 43.9 bits (102), Expect = 8e-04 Identities = 28/71 (39%), Positives = 31/71 (43%), Gaps = 9/71 (12%) Query: 44 PPTAALAPGAPRAARGSVPLQPPLPPAALGAYSGGAGPIRHHHPAHHFHHHGQAQPGLHP 103 PP+ A PRA R + PP PAA A + AGP R P A P Sbjct: 159 PPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPP---------AVAAREP 209 Query: 104 PLPPPPPPQLP 114 PLPPPP P P Sbjct: 210 PLPPPPQPPAP 220 Score = 35.8 bits (81), Expect = 0.23 Identities = 41/160 (25%), Positives = 61/160 (38%), Gaps = 20/160 (12%) Query: 902 PPPSALLPSPTFVPPMVPSLYPVSLYSRAMGSMPLPPQGRSRGFAGLHP-----IPPQGG 956 PPP+ P P PP P P + +P PPQ + P PP+GG Sbjct: 180 PPPAPAAP-PAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPPEGG 238 Query: 957 KLEIAGM--------VVGQWAGSRSSRGRGSFGMQVVSVGGPGKGHGK-EQTGRGSKGHK 1007 + G VV GS + GR + G + G+ E+T G+ Sbjct: 239 AVRAGGAARPVSLREVVRYLGGSGGAGGRLTRGRVQGLLEEEAAARGRLERTRLGALALP 298 Query: 1008 KGNKQGSSDGVSKSLELHQGRSRSQVNGNSGALIKEEKSD 1047 +G++ G + + + SRS+ G L KEE+ D Sbjct: 299 RGDRPGRAPPAASARP-----SRSKRGGEERVLEKEEEED 333 Score = 33.5 bits (75), Expect = 1.1 Identities = 29/90 (32%), Positives = 32/90 (35%), Gaps = 15/90 (16%) Query: 42 QLPPTAALAPGAPRAARGSVPL----------QPPLPPAALGAYSGGAGPIRHHHPAHHF 91 Q P A P PRA RG+ PP PPA + A + P A Sbjct: 100 QPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAP 159 Query: 92 HHHGQAQPG-----LHPPLPPPPPPQLPGA 116 G AQPG P PPP P P A Sbjct: 160 PSPGPAQPGPRAQRAAPLAAPPPAPAAPPA 189 Score = 30.8 bits (68), Expect = 7.3 Identities = 30/88 (34%), Positives = 32/88 (36%), Gaps = 19/88 (21%) Query: 44 PPTAALAP-GAPRAARGSVPLQ---PPLPPAALGAYSGGAGPIRHHHPAHHFHHHGQAQP 99 PP AP GAP AA + P PP PPA + A A P R A Sbjct: 108 PPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAA----AAPARAPRAA----------- 152 Query: 100 GLHPPLPPPPPPQLPGARVLVDAGSALP 127 PP P P PG R A A P Sbjct: 153 AAAATAPPSPGPAQPGPRAQRAAPLAAP 180 >gi|124107614 PR domain containing 13 [Homo sapiens] Length = 707 Score = 42.7 bits (99), Expect = 0.002 Identities = 22/47 (46%), Positives = 26/47 (55%), Gaps = 4/47 (8%) Query: 68 PPAALGAYSGGAGPIRHHHPAHHFHHHGQAQPGLHPPLPPPPPPQLP 114 P + + +GGAG HHH HH HHH + L PPPPPP LP Sbjct: 339 PGSGENSAAGGAG--HHHH--HHAHHHHHPKCLLAGDPPPPPPPGLP 381 Score = 30.8 bits (68), Expect = 7.3 Identities = 21/49 (42%), Positives = 25/49 (51%), Gaps = 8/49 (16%) Query: 37 QHLHRQLPPTAALAPGAPRAA---RGSVPLQ----PPLPPAALGAYSGG 78 +H+ R PP AA PGA A +PL+ PPL P L AY GG Sbjct: 403 KHVERA-PPAAAALPGARYAQLPPAPGLPLERCALPPLDPGGLKAYPGG 450 >gi|12751477 forkhead box L2 [Homo sapiens] Length = 376 Score = 42.4 bits (98), Expect = 0.002 Identities = 35/97 (36%), Positives = 39/97 (40%), Gaps = 30/97 (30%) Query: 47 AALAPGAPRAARGSVPLQPP--------------LPPAALGAYSGGAGPIR------HHH 86 AA PG+P AA L P LPP + +Y+G GP H H Sbjct: 232 AAAGPGSPGAAAVVKGLAGPAASYGPYTRVQSMALPPGVVNSYNGLGGPPAAPPPPPHPH 291 Query: 87 PAHHFHH-HGQAQPGLHPPLPP------PPPPQLPGA 116 P H HH H A P PP PP PPP QL A Sbjct: 292 PHPHAHHLHAAAAP---PPAPPHHGAAAPPPGQLSPA 325 >gi|47132620 keratin 2 [Homo sapiens] Length = 639 Score = 42.0 bits (97), Expect = 0.003 Identities = 33/92 (35%), Positives = 42/92 (45%), Gaps = 8/92 (8%) Query: 939 QGRSRGFAGLHPIPPQGGKLEIAGMVVGQWAGSRSSRGRGSFGMQVVSVGGPGKGHGKEQ 998 Q SRG +G GG + G G +G R G GS G +S GG G G GK Sbjct: 545 QSGSRGGSG------GGGSISGGGYGSGGGSGGRYGSGGGSKGGS-ISGGGYGSGGGKHS 597 Query: 999 TGRGSK-GHKKGNKQGSSDGVSKSLELHQGRS 1029 +G GS+ G G GS G S S++ G + Sbjct: 598 SGGGSRGGSSSGGGYGSGGGGSSSVKGSSGEA 629 >gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] Length = 424 Score = 41.2 bits (95), Expect = 0.005 Identities = 33/101 (32%), Positives = 37/101 (36%), Gaps = 34/101 (33%) Query: 43 LPPTAALAPGAPRAARGSVPLQPPLPPAALGAYSGGAGPIRHHHPAH-HFHHH-----GQ 96 +PP AL PG P A PP+PP A G AG HP H H H H G Sbjct: 247 VPPPGALPPGIPPAMP-----PPPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPGGM 301 Query: 97 AQPGL--------------HPPLPPP---------PPPQLP 114 PG+ HP PP PPP +P Sbjct: 302 PHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQPPPRPPPGMP 342 >gi|32307177 forkhead box G1 [Homo sapiens] Length = 489 Score = 41.2 bits (95), Expect = 0.005 Identities = 18/31 (58%), Positives = 18/31 (58%), Gaps = 6/31 (19%) Query: 85 HHPAHHFHHHGQAQPGLHPPLP---PPPPPQ 112 HHP HH HHH HPP P PPPPPQ Sbjct: 43 HHPQHHHHHHHHHH---HPPPPAPQPPPPPQ 70 Score = 40.0 bits (92), Expect = 0.012 Identities = 18/38 (47%), Positives = 18/38 (47%), Gaps = 4/38 (10%) Query: 81 PIRHHHPAHHFHHHGQAQPGLHPP----LPPPPPPQLP 114 P HHH HH HH P PP PPPPPP P Sbjct: 45 PQHHHHHHHHHHHPPPPAPQPPPPPQQQQPPPPPPPAP 82 Score = 39.7 bits (91), Expect = 0.016 Identities = 20/43 (46%), Positives = 21/43 (48%), Gaps = 8/43 (18%) Query: 83 RHHHPAHHFHHHGQA---QPG-----LHPPLPPPPPPQLPGAR 117 +HHH HH HHH QP PP PPPP PQ P R Sbjct: 46 QHHHHHHHHHHHPPPPAPQPPPPPQQQQPPPPPPPAPQPPQTR 88 Score = 38.9 bits (89), Expect = 0.027 Identities = 15/29 (51%), Positives = 15/29 (51%) Query: 84 HHHPAHHFHHHGQAQPGLHPPLPPPPPPQ 112 HH HH HHH P P PPPPP Q Sbjct: 43 HHPQHHHHHHHHHHHPPPPAPQPPPPPQQ 71 Score = 34.7 bits (78), Expect = 0.51 Identities = 26/81 (32%), Positives = 30/81 (37%), Gaps = 14/81 (17%) Query: 38 HLHRQLPPTAALAPGAPRAARGSVPLQP-PLPPAALGAYSGGAGPIRHHHPAHHFHHHGQ 96 H H PP A P P+ + P P P PP GA + G Sbjct: 53 HHHHHPPPPAPQPPPPPQQQQPPPPPPPAPQPPQTRGAPAAD-------------DDKGP 99 Query: 97 AQPGLHPPLPPPPPPQLPGAR 117 Q L PP PPPP L GA+ Sbjct: 100 QQLLLPPPPPPPPAAALDGAK 120 Score = 32.0 bits (71), Expect = 3.3 Identities = 38/132 (28%), Positives = 49/132 (37%), Gaps = 35/132 (26%) Query: 900 NHPPPSALLPSPTFVPPMVPSLYPVSLYSRAMGSMPLPPQGRSRGFAG---------LHP 950 +HPPP A P P P P + P PPQ R A L P Sbjct: 56 HHPPPPAPQPPPPPQQQQPPPPPPPA---------PQPPQTRGAPAADDDKGPQQLLLPP 106 Query: 951 IPPQGGKLEIAGMVVGQWAGSRSSRGRGSFGMQVVSVGGPGK----GHGKEQTGRGSKG- 1005 PP + G A + G+G G GGPG+ G +++ G G+ G Sbjct: 107 PPPPPPAAALDG------AKADGLGGKGEPG------GGPGELAPVGPDEKEKGAGAGGE 154 Query: 1006 HKKGNKQGSSDG 1017 KKG +G DG Sbjct: 155 EKKGAGEGGKDG 166 >gi|66730481 neuregulin 3 [Homo sapiens] Length = 696 Score = 40.8 bits (94), Expect = 0.007 Identities = 53/200 (26%), Positives = 79/200 (39%), Gaps = 22/200 (11%) Query: 356 VVIKAVSEYVSSIKDPSNLDVVGKDVFKQSQSRTEDKIERFKKAVEYYSVTTKLSSLPVG 415 +V+ +V EYV + D + +G+D F S K F KA+E + TT +S P Sbjct: 89 IVVGSVKEYVPT--DLVDSKGMGQDPFFLS------KPSSFPKAMETTTTTTSTTS-PAT 139 Query: 416 PSFLGFRNNRLGNPPLPRNQVGTISAGKPMF-SHQVPQKVK--------YPPPFPVGPNS 466 PS G ++R N R + TI+ F H+VP + P V + Sbjct: 140 PSAGGAASSRTPNRISTR--LTTITRAPTRFPGHRVPIRASPRSTTARNTAAPATVPSTT 197 Query: 467 SLLFSSHALGESHAFSEDPMLQNSPFANWAVSYDSSASQFPNYLPSKASPPLGPDSSHSS 526 + FSS LG P Q P +W + +++S + PS P +S SS Sbjct: 198 APFFSSSTLGSRPPVPGTPSTQAMP--SWPTAAYATSSYLHDSTPSWTLSPFQDAASSSS 255 Query: 527 SSDGDEPNGASSDHITEAFH 546 SS + FH Sbjct: 256 SSSSSATTTTPETSTSPKFH 275 >gi|22027622 TNF receptor-associated factor 4 [Homo sapiens] Length = 470 Score = 40.8 bits (94), Expect = 0.007 Identities = 23/65 (35%), Positives = 32/65 (49%), Gaps = 5/65 (7%) Query: 529 DGDEPNGASSDHITEAFHHQPEWGNPNRDRGSWAQPVDTGVSEASLGDGEPHIPSLLSMS 588 D +P A H+TE FH P W N + G+W +D E+SLG G P S + Sbjct: 392 DQSDPGLAKPQHVTETFHPDPNWKNFQKP-GTWRGSLD----ESSLGFGYPKFISHQDIR 446 Query: 589 TRNHM 593 RN++ Sbjct: 447 KRNYV 451 >gi|161169015 neuron navigator 2 isoform 3 [Homo sapiens] Length = 2365 Score = 40.8 bits (94), Expect = 0.007 Identities = 31/105 (29%), Positives = 41/105 (39%), Gaps = 20/105 (19%) Query: 32 RQQQQQHLHRQLPPTAALAPGAPRAARGSVPLQP-PLPPAALGAYSGGAGPIRHHHPAHH 90 +Q Q+QHL LPP + GAP + P Q P+ P A P + H PA H Sbjct: 131 QQPQKQHLSSPLPPAVSQVAGAPSQCQAGTPQQQVPVTPQA---------PCQPHQPAPH 181 Query: 91 FHHHGQAQPGLHPPLPPPPPPQLPGARVLVDAGSALPRLYGGYQT 135 QA+ +LPG V A + + GG T Sbjct: 182 QQSKAQAE----------MQSRLPGPTARVSAAGSEAKTRGGSTT 216 >gi|161169013 neuron navigator 2 isoform 1 [Homo sapiens] Length = 2432 Score = 40.8 bits (94), Expect = 0.007 Identities = 31/105 (29%), Positives = 41/105 (39%), Gaps = 20/105 (19%) Query: 32 RQQQQQHLHRQLPPTAALAPGAPRAARGSVPLQP-PLPPAALGAYSGGAGPIRHHHPAHH 90 +Q Q+QHL LPP + GAP + P Q P+ P A P + H PA H Sbjct: 195 QQPQKQHLSSPLPPAVSQVAGAPSQCQAGTPQQQVPVTPQA---------PCQPHQPAPH 245 Query: 91 FHHHGQAQPGLHPPLPPPPPPQLPGARVLVDAGSALPRLYGGYQT 135 QA+ +LPG V A + + GG T Sbjct: 246 QQSKAQAE----------MQSRLPGPTARVSAAGSEAKTRGGSTT 280 >gi|38044282 neuron navigator 2 isoform 2 [Homo sapiens] Length = 2429 Score = 40.8 bits (94), Expect = 0.007 Identities = 31/105 (29%), Positives = 41/105 (39%), Gaps = 20/105 (19%) Query: 32 RQQQQQHLHRQLPPTAALAPGAPRAARGSVPLQP-PLPPAALGAYSGGAGPIRHHHPAHH 90 +Q Q+QHL LPP + GAP + P Q P+ P A P + H PA H Sbjct: 195 QQPQKQHLSSPLPPAVSQVAGAPSQCQAGTPQQQVPVTPQA---------PCQPHQPAPH 245 Query: 91 FHHHGQAQPGLHPPLPPPPPPQLPGARVLVDAGSALPRLYGGYQT 135 QA+ +LPG V A + + GG T Sbjct: 246 QQSKAQAE----------MQSRLPGPTARVSAAGSEAKTRGGSTT 280 >gi|189027090 cytoplasmic polyadenylation element binding protein 4 [Homo sapiens] Length = 729 Score = 40.8 bits (94), Expect = 0.007 Identities = 19/45 (42%), Positives = 22/45 (48%), Gaps = 2/45 (4%) Query: 69 PAALGAYSGGAGPIRHHHP--AHHFHHHGQAQPGLHPPLPPPPPP 111 P G++S GP+ HHP H HHH Q Q P P PPP Sbjct: 216 PGFGGSFSPQIGPLSQHHPHHPHFQHHHSQHQQQRRSPASPHPPP 260 >gi|169636435 caudal type homeobox 2 [Homo sapiens] Length = 313 Score = 40.4 bits (93), Expect = 0.009 Identities = 29/66 (43%), Positives = 31/66 (46%), Gaps = 6/66 (9%) Query: 50 APGAPRAARGSVP--LQPPLPPAALGAYSGGAGPIRHHHPAHHFHHHGQA---QPGLHPP 104 APG AA +V L P AA+G YS A HHHP HH HH A GL Sbjct: 81 APGGAAAAANAVAHGLNGGSPAAAMG-YSSPADYHPHHHPHHHPHHPAAAPSCASGLLQT 139 Query: 105 LPPPPP 110 L P PP Sbjct: 140 LNPGPP 145 Score = 30.4 bits (67), Expect = 9.6 Identities = 12/19 (63%), Positives = 12/19 (63%) Query: 96 QAQPGLHPPLPPPPPPQLP 114 Q Q PP PPPPPPQ P Sbjct: 250 QQQQQQQPPQPPPPPPQPP 268 >gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens] Length = 502 Score = 40.4 bits (93), Expect = 0.009 Identities = 28/72 (38%), Positives = 32/72 (44%), Gaps = 17/72 (23%) Query: 44 PPTAALAPGAPRAARGSVPLQPPLPPAALGAYSGGAGPIRHHHPAHHFHHHGQAQPGLHP 103 PPT G P RG P PP PPA +G +GP+ P G P + P Sbjct: 353 PPTPR---GPPPPGRGGPP--PPPPPA-----TGRSGPLPPPPP-------GAGGPPMPP 395 Query: 104 PLPPPPPPQLPG 115 P PPPPPP G Sbjct: 396 PPPPPPPPPSSG 407 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.318 0.135 0.423 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 51,646,108 Number of Sequences: 37866 Number of extensions: 2903419 Number of successful extensions: 22520 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 132 Number of HSP's successfully gapped in prelim test: 471 Number of HSP's that attempted gapping in prelim test: 17293 Number of HSP's gapped (non-prelim): 4261 length of query: 1096 length of database: 18,247,518 effective HSP length: 113 effective length of query: 983 effective length of database: 13,968,660 effective search space: 13731192780 effective search space used: 13731192780 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.