BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|156630992 OTU domain containing 4 protein isoform 3 [Homo sapiens] (1049 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|156630992 OTU domain containing 4 protein isoform 3 [Homo sap... 2146 0.0 gi|40807496 OTU domain containing 4 protein isoform 1 [Homo sapi... 2140 0.0 gi|8923779 OTU domain containing 4 protein isoform 2 [Homo sapiens] 296 9e-80 gi|55741677 SET domain containing 1A [Homo sapiens] 57 9e-08 gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 56 2e-07 gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 56 2e-07 gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 56 2e-07 gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithora... 52 4e-06 gi|119943102 CREB binding protein isoform b [Homo sapiens] 50 1e-05 gi|119943104 CREB binding protein isoform a [Homo sapiens] 50 1e-05 gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 50 1e-05 gi|187829452 autism susceptibility candidate 2 isoform 2 [Homo s... 49 2e-05 gi|17864090 autism susceptibility candidate 2 isoform 1 [Homo sa... 49 2e-05 gi|209862789 microtubule associated monoxygenase, calponin and L... 47 9e-05 gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 46 2e-04 gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 46 2e-04 gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 46 2e-04 gi|116284392 mucin 2 precursor [Homo sapiens] 45 4e-04 gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap... 45 4e-04 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 44 6e-04 gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2... 44 8e-04 gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1... 44 8e-04 gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens] 43 0.001 gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 42 0.002 gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 42 0.002 gi|149158690 HLA-B associated transcript-2 [Homo sapiens] 42 0.002 gi|55953110 retinoblastoma protein-binding zinc finger protein i... 42 0.002 gi|20336260 retinoblastoma protein-binding zinc finger protein i... 42 0.002 gi|20336258 retinoblastoma protein-binding zinc finger protein i... 42 0.002 gi|47132519 Ras association and pleckstrin homology domains 1 is... 42 0.002 >gi|156630992 OTU domain containing 4 protein isoform 3 [Homo sapiens] Length = 1049 Score = 2146 bits (5561), Expect = 0.0 Identities = 1049/1049 (100%), Positives = 1049/1049 (100%) Query: 1 MACIHYLRENREKFEAFIEGSFEEYLKRLENPQEWVGQVEISALSLMYRKDFIIYREPNV 60 MACIHYLRENREKFEAFIEGSFEEYLKRLENPQEWVGQVEISALSLMYRKDFIIYREPNV Sbjct: 1 MACIHYLRENREKFEAFIEGSFEEYLKRLENPQEWVGQVEISALSLMYRKDFIIYREPNV 60 Query: 61 SPSQVTENNFPEKVLLCFSNGNHYDIVYPIKYKESSAMCQSLLYELLYEKVFKTDVSKIV 120 SPSQVTENNFPEKVLLCFSNGNHYDIVYPIKYKESSAMCQSLLYELLYEKVFKTDVSKIV Sbjct: 61 SPSQVTENNFPEKVLLCFSNGNHYDIVYPIKYKESSAMCQSLLYELLYEKVFKTDVSKIV 120 Query: 121 MELDTLEVADEDNSEISDSEDDSCKSKTAAAAADVNGFKPLSGNEQLKNNGNSTSLPLSR 180 MELDTLEVADEDNSEISDSEDDSCKSKTAAAAADVNGFKPLSGNEQLKNNGNSTSLPLSR Sbjct: 121 MELDTLEVADEDNSEISDSEDDSCKSKTAAAAADVNGFKPLSGNEQLKNNGNSTSLPLSR 180 Query: 181 KVLKSLNPAVYRNVEYEIWLKSKQAQQKRDYSIAAGLQYEVGDKCQVRLDHNGKFLNADV 240 KVLKSLNPAVYRNVEYEIWLKSKQAQQKRDYSIAAGLQYEVGDKCQVRLDHNGKFLNADV Sbjct: 181 KVLKSLNPAVYRNVEYEIWLKSKQAQQKRDYSIAAGLQYEVGDKCQVRLDHNGKFLNADV 240 Query: 241 QGIHSENGPVLVEELGKKHTSKNLKAPPPESWNTVSGKKMKKPSTSGQNFHSDVDYRGPK 300 QGIHSENGPVLVEELGKKHTSKNLKAPPPESWNTVSGKKMKKPSTSGQNFHSDVDYRGPK Sbjct: 241 QGIHSENGPVLVEELGKKHTSKNLKAPPPESWNTVSGKKMKKPSTSGQNFHSDVDYRGPK 300 Query: 301 NPSKPIKAPSALPPRLQHPSGVRQHAFSSHSSGSQSQKFSSEHKNLSRTPSQIIRKPDRE 360 NPSKPIKAPSALPPRLQHPSGVRQHAFSSHSSGSQSQKFSSEHKNLSRTPSQIIRKPDRE Sbjct: 301 NPSKPIKAPSALPPRLQHPSGVRQHAFSSHSSGSQSQKFSSEHKNLSRTPSQIIRKPDRE 360 Query: 361 RVEDFDHTSRESNYFGLSPEERREKQAIEESRLLYEIQNRDEQAFPALSSSSVNQSASQS 420 RVEDFDHTSRESNYFGLSPEERREKQAIEESRLLYEIQNRDEQAFPALSSSSVNQSASQS Sbjct: 361 RVEDFDHTSRESNYFGLSPEERREKQAIEESRLLYEIQNRDEQAFPALSSSSVNQSASQS 420 Query: 421 SNPCVQRKSSHVGDRKGSRRRMDTEERKDKDSIHGHSQLDKRPEPSTLENITDDKYATVS 480 SNPCVQRKSSHVGDRKGSRRRMDTEERKDKDSIHGHSQLDKRPEPSTLENITDDKYATVS Sbjct: 421 SNPCVQRKSSHVGDRKGSRRRMDTEERKDKDSIHGHSQLDKRPEPSTLENITDDKYATVS 480 Query: 481 SPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEPTTFG 540 SPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEPTTFG Sbjct: 481 SPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEPTTFG 540 Query: 541 PTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSIQAVNQPLMPLPQTLSLYQDPL 600 PTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSIQAVNQPLMPLPQTLSLYQDPL Sbjct: 541 PTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSIQAVNQPLMPLPQTLSLYQDPL 600 Query: 601 YPGFPCNEKGDRAIVPPYSLCQTGEDLPKDKNILRFFFNLGVKAYSCPMWAPHSYLYPLH 660 YPGFPCNEKGDRAIVPPYSLCQTGEDLPKDKNILRFFFNLGVKAYSCPMWAPHSYLYPLH Sbjct: 601 YPGFPCNEKGDRAIVPPYSLCQTGEDLPKDKNILRFFFNLGVKAYSCPMWAPHSYLYPLH 660 Query: 661 QAYLAACRMYPKVPVPVYPHNPWFQEAPAAQNESDCTCTDAHFPMQTEASVNGQMPQPEI 720 QAYLAACRMYPKVPVPVYPHNPWFQEAPAAQNESDCTCTDAHFPMQTEASVNGQMPQPEI Sbjct: 661 QAYLAACRMYPKVPVPVYPHNPWFQEAPAAQNESDCTCTDAHFPMQTEASVNGQMPQPEI 720 Query: 721 GPPTFSSPLVIPPSQVSESHGQLSYQADLESETPGQLLHADYEESLSGKNMFPQPSFGPN 780 GPPTFSSPLVIPPSQVSESHGQLSYQADLESETPGQLLHADYEESLSGKNMFPQPSFGPN Sbjct: 721 GPPTFSSPLVIPPSQVSESHGQLSYQADLESETPGQLLHADYEESLSGKNMFPQPSFGPN 780 Query: 781 PFLGPVPIAPPFFPHVWYGYPFQGFIENPVMRQNIVLPSDEKGELDLSLENLDLSKDCGS 840 PFLGPVPIAPPFFPHVWYGYPFQGFIENPVMRQNIVLPSDEKGELDLSLENLDLSKDCGS Sbjct: 781 PFLGPVPIAPPFFPHVWYGYPFQGFIENPVMRQNIVLPSDEKGELDLSLENLDLSKDCGS 840 Query: 841 VSTVDEFPEARGEHVHSLPEASVSSKPDEGRTEQSSQTRKADTALASIPPVAEGKAHPPT 900 VSTVDEFPEARGEHVHSLPEASVSSKPDEGRTEQSSQTRKADTALASIPPVAEGKAHPPT Sbjct: 841 VSTVDEFPEARGEHVHSLPEASVSSKPDEGRTEQSSQTRKADTALASIPPVAEGKAHPPT 900 Query: 901 QILNRERETVPVELEPKRTIQSLKEKTEKVKDPKTAADVVSPGANSVDSRVQRPKEESSE 960 QILNRERETVPVELEPKRTIQSLKEKTEKVKDPKTAADVVSPGANSVDSRVQRPKEESSE Sbjct: 901 QILNRERETVPVELEPKRTIQSLKEKTEKVKDPKTAADVVSPGANSVDSRVQRPKEESSE 960 Query: 961 DENEVSNILRSGRSKQFYNQTYGSRKYKSDWGYSGRGGYQHVRSEESWKGQPSRSRDEGY 1020 DENEVSNILRSGRSKQFYNQTYGSRKYKSDWGYSGRGGYQHVRSEESWKGQPSRSRDEGY Sbjct: 961 DENEVSNILRSGRSKQFYNQTYGSRKYKSDWGYSGRGGYQHVRSEESWKGQPSRSRDEGY 1020 Query: 1021 QYHRNVRGRPFRGDRRRSGMGDGHRGQHT 1049 QYHRNVRGRPFRGDRRRSGMGDGHRGQHT Sbjct: 1021 QYHRNVRGRPFRGDRRRSGMGDGHRGQHT 1049 >gi|40807496 OTU domain containing 4 protein isoform 1 [Homo sapiens] Length = 1048 Score = 2140 bits (5544), Expect = 0.0 Identities = 1048/1049 (99%), Positives = 1048/1049 (99%), Gaps = 1/1049 (0%) Query: 1 MACIHYLRENREKFEAFIEGSFEEYLKRLENPQEWVGQVEISALSLMYRKDFIIYREPNV 60 MACIHYLRENREKFEAFIEGSFEEYLKRLENPQEWVGQVEISALSLMYRKDFIIYREPNV Sbjct: 1 MACIHYLRENREKFEAFIEGSFEEYLKRLENPQEWVGQVEISALSLMYRKDFIIYREPNV 60 Query: 61 SPSQVTENNFPEKVLLCFSNGNHYDIVYPIKYKESSAMCQSLLYELLYEKVFKTDVSKIV 120 SPSQVTENNFPEKVLLCFSNGNHYDIVYPIKYKESSAMCQSLLYELLYEKVFKTDVSKIV Sbjct: 61 SPSQVTENNFPEKVLLCFSNGNHYDIVYPIKYKESSAMCQSLLYELLYEKVFKTDVSKIV 120 Query: 121 MELDTLEVADEDNSEISDSEDDSCKSKTAAAAADVNGFKPLSGNEQLKNNGNSTSLPLSR 180 MELDTLEVADEDNSEISDSEDDSCKSKTAAAAADVNGFKPLSGNE LKNNGNSTSLPLSR Sbjct: 121 MELDTLEVADEDNSEISDSEDDSCKSKTAAAAADVNGFKPLSGNE-LKNNGNSTSLPLSR 179 Query: 181 KVLKSLNPAVYRNVEYEIWLKSKQAQQKRDYSIAAGLQYEVGDKCQVRLDHNGKFLNADV 240 KVLKSLNPAVYRNVEYEIWLKSKQAQQKRDYSIAAGLQYEVGDKCQVRLDHNGKFLNADV Sbjct: 180 KVLKSLNPAVYRNVEYEIWLKSKQAQQKRDYSIAAGLQYEVGDKCQVRLDHNGKFLNADV 239 Query: 241 QGIHSENGPVLVEELGKKHTSKNLKAPPPESWNTVSGKKMKKPSTSGQNFHSDVDYRGPK 300 QGIHSENGPVLVEELGKKHTSKNLKAPPPESWNTVSGKKMKKPSTSGQNFHSDVDYRGPK Sbjct: 240 QGIHSENGPVLVEELGKKHTSKNLKAPPPESWNTVSGKKMKKPSTSGQNFHSDVDYRGPK 299 Query: 301 NPSKPIKAPSALPPRLQHPSGVRQHAFSSHSSGSQSQKFSSEHKNLSRTPSQIIRKPDRE 360 NPSKPIKAPSALPPRLQHPSGVRQHAFSSHSSGSQSQKFSSEHKNLSRTPSQIIRKPDRE Sbjct: 300 NPSKPIKAPSALPPRLQHPSGVRQHAFSSHSSGSQSQKFSSEHKNLSRTPSQIIRKPDRE 359 Query: 361 RVEDFDHTSRESNYFGLSPEERREKQAIEESRLLYEIQNRDEQAFPALSSSSVNQSASQS 420 RVEDFDHTSRESNYFGLSPEERREKQAIEESRLLYEIQNRDEQAFPALSSSSVNQSASQS Sbjct: 360 RVEDFDHTSRESNYFGLSPEERREKQAIEESRLLYEIQNRDEQAFPALSSSSVNQSASQS 419 Query: 421 SNPCVQRKSSHVGDRKGSRRRMDTEERKDKDSIHGHSQLDKRPEPSTLENITDDKYATVS 480 SNPCVQRKSSHVGDRKGSRRRMDTEERKDKDSIHGHSQLDKRPEPSTLENITDDKYATVS Sbjct: 420 SNPCVQRKSSHVGDRKGSRRRMDTEERKDKDSIHGHSQLDKRPEPSTLENITDDKYATVS 479 Query: 481 SPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEPTTFG 540 SPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEPTTFG Sbjct: 480 SPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEPTTFG 539 Query: 541 PTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSIQAVNQPLMPLPQTLSLYQDPL 600 PTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSIQAVNQPLMPLPQTLSLYQDPL Sbjct: 540 PTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSIQAVNQPLMPLPQTLSLYQDPL 599 Query: 601 YPGFPCNEKGDRAIVPPYSLCQTGEDLPKDKNILRFFFNLGVKAYSCPMWAPHSYLYPLH 660 YPGFPCNEKGDRAIVPPYSLCQTGEDLPKDKNILRFFFNLGVKAYSCPMWAPHSYLYPLH Sbjct: 600 YPGFPCNEKGDRAIVPPYSLCQTGEDLPKDKNILRFFFNLGVKAYSCPMWAPHSYLYPLH 659 Query: 661 QAYLAACRMYPKVPVPVYPHNPWFQEAPAAQNESDCTCTDAHFPMQTEASVNGQMPQPEI 720 QAYLAACRMYPKVPVPVYPHNPWFQEAPAAQNESDCTCTDAHFPMQTEASVNGQMPQPEI Sbjct: 660 QAYLAACRMYPKVPVPVYPHNPWFQEAPAAQNESDCTCTDAHFPMQTEASVNGQMPQPEI 719 Query: 721 GPPTFSSPLVIPPSQVSESHGQLSYQADLESETPGQLLHADYEESLSGKNMFPQPSFGPN 780 GPPTFSSPLVIPPSQVSESHGQLSYQADLESETPGQLLHADYEESLSGKNMFPQPSFGPN Sbjct: 720 GPPTFSSPLVIPPSQVSESHGQLSYQADLESETPGQLLHADYEESLSGKNMFPQPSFGPN 779 Query: 781 PFLGPVPIAPPFFPHVWYGYPFQGFIENPVMRQNIVLPSDEKGELDLSLENLDLSKDCGS 840 PFLGPVPIAPPFFPHVWYGYPFQGFIENPVMRQNIVLPSDEKGELDLSLENLDLSKDCGS Sbjct: 780 PFLGPVPIAPPFFPHVWYGYPFQGFIENPVMRQNIVLPSDEKGELDLSLENLDLSKDCGS 839 Query: 841 VSTVDEFPEARGEHVHSLPEASVSSKPDEGRTEQSSQTRKADTALASIPPVAEGKAHPPT 900 VSTVDEFPEARGEHVHSLPEASVSSKPDEGRTEQSSQTRKADTALASIPPVAEGKAHPPT Sbjct: 840 VSTVDEFPEARGEHVHSLPEASVSSKPDEGRTEQSSQTRKADTALASIPPVAEGKAHPPT 899 Query: 901 QILNRERETVPVELEPKRTIQSLKEKTEKVKDPKTAADVVSPGANSVDSRVQRPKEESSE 960 QILNRERETVPVELEPKRTIQSLKEKTEKVKDPKTAADVVSPGANSVDSRVQRPKEESSE Sbjct: 900 QILNRERETVPVELEPKRTIQSLKEKTEKVKDPKTAADVVSPGANSVDSRVQRPKEESSE 959 Query: 961 DENEVSNILRSGRSKQFYNQTYGSRKYKSDWGYSGRGGYQHVRSEESWKGQPSRSRDEGY 1020 DENEVSNILRSGRSKQFYNQTYGSRKYKSDWGYSGRGGYQHVRSEESWKGQPSRSRDEGY Sbjct: 960 DENEVSNILRSGRSKQFYNQTYGSRKYKSDWGYSGRGGYQHVRSEESWKGQPSRSRDEGY 1019 Query: 1021 QYHRNVRGRPFRGDRRRSGMGDGHRGQHT 1049 QYHRNVRGRPFRGDRRRSGMGDGHRGQHT Sbjct: 1020 QYHRNVRGRPFRGDRRRSGMGDGHRGQHT 1048 >gi|8923779 OTU domain containing 4 protein isoform 2 [Homo sapiens] Length = 145 Score = 296 bits (757), Expect = 9e-80 Identities = 145/145 (100%), Positives = 145/145 (100%) Query: 1 MACIHYLRENREKFEAFIEGSFEEYLKRLENPQEWVGQVEISALSLMYRKDFIIYREPNV 60 MACIHYLRENREKFEAFIEGSFEEYLKRLENPQEWVGQVEISALSLMYRKDFIIYREPNV Sbjct: 1 MACIHYLRENREKFEAFIEGSFEEYLKRLENPQEWVGQVEISALSLMYRKDFIIYREPNV 60 Query: 61 SPSQVTENNFPEKVLLCFSNGNHYDIVYPIKYKESSAMCQSLLYELLYEKVFKTDVSKIV 120 SPSQVTENNFPEKVLLCFSNGNHYDIVYPIKYKESSAMCQSLLYELLYEKVFKTDVSKIV Sbjct: 61 SPSQVTENNFPEKVLLCFSNGNHYDIVYPIKYKESSAMCQSLLYELLYEKVFKTDVSKIV 120 Query: 121 MELDTLEVADEDNSEISDSEDDSCK 145 MELDTLEVADEDNSEISDSEDDSCK Sbjct: 121 MELDTLEVADEDNSEISDSEDDSCK 145 >gi|55741677 SET domain containing 1A [Homo sapiens] Length = 1707 Score = 57.0 bits (136), Expect = 9e-08 Identities = 89/414 (21%), Positives = 150/414 (36%), Gaps = 55/414 (13%) Query: 184 KSLNPAVYRNVEY---EIWLKSKQAQQKRDYSIAAGLQYEVGDKCQVRLDHNGKFLNADV 240 + LN + NV + + W +SK+ + K + AA Q + DK + +L G D Sbjct: 808 RDLNRKMVENVAFGAFDQWWESKEEKAK-PFQNAAKQQAKEEDKEKTKLKEPGLLSLVDW 866 Query: 241 QGIHSENGPVLVEELG--------KKHTSKNLKAPPPESWNTVSGKKMKKPSTSGQNFHS 292 G +E + S +K P + S +K +PST + Sbjct: 867 A---KSGGTTGIEAFAFGSGLRGALRLPSFKVKRKEPSEISEASEEKRPRPSTPAEEDED 923 Query: 293 DVDYRGPKNPSKPIKAPSALPPRLQHPSGVRQ----HAFSSHSSGSQSQKFSSEHKNLSR 348 D + K +P + P PP+ G Q +F+ S G ++ + SS K+ Sbjct: 924 DPEQE--KEAGEPGR-PGTKPPKRDEERGKTQGKHRKSFALDSEGEEASQESSSEKDEED 980 Query: 349 TPSQIIRKPDRERVEDFDHTSRESNYFGLSPEERREKQAIEESRLLYEIQNRDEQAFPAL 408 + D +R E D T +E+ +S E E + + L + ++ + Sbjct: 981 DEED---EEDEDREEAVDTTKKETE---VSDGEDEESDSSSKCSLYADSDGENDSTSDSE 1034 Query: 409 SSSSVNQSASQSSNPCVQRKSSHVGDRKGSRRRMDTEERKDKDSIHGHSQLDKR----PE 464 SSSS + S+S SS+ SS S + EE +++ + + R P Sbjct: 1035 SSSSSSSSSSSSSS------SSSSSSSSSSESSSEDEEEEERPAALPSASPPPREVPVPT 1088 Query: 465 PSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAVPS 524 P+ +E ++ A SP P + S + PA P P+ P Sbjct: 1089 PAPVEVPVPERVAG-------------SPVTPLPEQEASPARPA----GPTEESPPSAPL 1131 Query: 525 LPATVPAWPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVS 578 P PA P P +PIP+L + + + P P P + Sbjct: 1132 RPPEPPAGPPAPAPRPDERPSSPIPLLPPPKKRRKTVSFSAIEVVPAPEPPPAT 1185 Score = 33.9 bits (76), Expect = 0.83 Identities = 58/302 (19%), Positives = 98/302 (32%), Gaps = 45/302 (14%) Query: 326 AFSSHSSGSQSQKFSSEHKNLSRTPSQIIRKPDRERVEDFDHTSRESNYFGLSPEE---R 382 A S ++G ++ F S + R PS +++ + + + R +E Sbjct: 867 AKSGGTTGIEAFAFGSGLRGALRLPSFKVKRKEPSEISEASEEKRPRPSTPAEEDEDDPE 926 Query: 383 REKQAIEESRLLYEIQNRDEQAFP-------ALSSSSVNQSASQSSNPCVQRKSSHVGDR 435 +EK+A E R + RDE+ + + S + ASQ S+ + + Sbjct: 927 QEKEAGEPGRPGTKPPKRDEERGKTQGKHRKSFALDSEGEEASQESSSEKDEEDDEEDEE 986 Query: 436 KGSRRRMDTEERKDKDSIHGHSQLDKRPEPSTLENITDDKYATVSSPSKSKKLECPSPAE 495 R +K+ + G + +L +D + + S S S + Sbjct: 987 DEDREEAVDTTKKETEVSDGEDEESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSSSS 1046 Query: 496 QKPAEHVSLSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEPTTFGPTGVPAPIPVLSVTQ 555 + S S+ E PA +LP+ P P VP P P Sbjct: 1047 SSSSSSSSSSSSESSSEDEEEEERPA--ALPSASPP---------PREVPVPTPA----- 1090 Query: 556 TLTTGPDSAVSQAHLTPSPVPVSIQAVNQPLMPLPQTLSLYQDPLYPGFPCNEKGDRAIV 615 P VPV + P+ PLP+ + P P P E A + Sbjct: 1091 ----------------PVEVPVPERVAGSPVTPLPEQEA---SPARPAGPTEESPPSAPL 1131 Query: 616 PP 617 P Sbjct: 1132 RP 1133 >gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] Length = 1012 Score = 56.2 bits (134), Expect = 2e-07 Identities = 107/450 (23%), Positives = 152/450 (33%), Gaps = 71/450 (15%) Query: 406 PALSSSSVNQSASQ----SSNPCVQRKSSHVGDRKGSRRRM--DTEERKDKDSIHGHSQL 459 P+ +S+S N S ++ S+ + SS + K R ++ DTEE S +Q Sbjct: 60 PSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQE 119 Query: 460 DKRPE-PSTLENITDDKYAT----------VSSPSKSKKLECPSPAEQKP-----AEHVS 503 RP PS E + D + + ++S PSP + + A+ Sbjct: 120 ISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQM 179 Query: 504 LSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEPTTFGPTGVPAP-IPVLSVTQTLTTGPD 562 L P L +P +TPA S P P P+ T T VP P S P Sbjct: 180 LQAQPPALQAP-TGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT 238 Query: 563 SAVSQAHL----------TPSPVPVSIQAVNQPLMPLPQTLSLYQDPLYPGFPCNEKGDR 612 + V H+ PSP P + + PL PL + P + P + +G Sbjct: 239 APVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPP 298 Query: 613 AIVPPYSLCQTGEDLPKDKNILRFFFNLGVKAYSCPMWAPHSYLYPLHQAYLAAC----- 667 P+SL Q G L F P+ + YP L A Sbjct: 299 G---PHSL-QAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQ 354 Query: 668 -----RMYPKVPVPVY------PHNPWFQEAPAAQNESDCTCTDAHFPMQTEASVNGQMP 716 R P P P+ P + PA Q H + S+N +P Sbjct: 355 SQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKH----PPHLSGPSPFSMNANLP 410 Query: 717 QPEIGPPTFSSPLVIPPSQVSESHGQLSYQADLESETPGQLLHADYEESLSG-------- 768 P P S PPS QL Q+ +P Q ++L Sbjct: 411 PPPALKPLSSLSTHHPPS-AHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPT 469 Query: 769 --KNMFPQPSFGPNPFL--GPVPIAPPFFP 794 + PQP F +PF+ GP PI PP P Sbjct: 470 GLHQVAPQPPFAQHPFVPGGPPPITPPTCP 499 Score = 35.8 bits (81), Expect = 0.22 Identities = 34/124 (27%), Positives = 53/124 (42%), Gaps = 8/124 (6%) Query: 848 PEARGEHVHSLPEASVSSKPDEGRTEQSSQTRKADTALASIPPVAEGKAHPPTQILNRER 907 P+ R ++ +S + P T SS KA+T S V E +A P + R+R Sbjct: 41 PDGRTSPINEDIRSSGRNSPSAAST--SSNDSKAETVKKSAKKVKE-EASSPLKSNKRQR 97 Query: 908 ETVPVELEPKRTIQSLKEKTEKVKDPKTAADVVSPGANSVDSRVQRPKEESSEDENEVSN 967 E V + E S K KT+++ P + ++ S DSR +E S D ++ Sbjct: 98 EKVASDTEEADRTSSKKTKTQEISRPNSPSE---GEGESSDSR--SVNDEGSSDPKDIDQ 152 Query: 968 ILRS 971 RS Sbjct: 153 DNRS 156 >gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 56.2 bits (134), Expect = 2e-07 Identities = 107/450 (23%), Positives = 152/450 (33%), Gaps = 71/450 (15%) Query: 406 PALSSSSVNQSASQ----SSNPCVQRKSSHVGDRKGSRRRM--DTEERKDKDSIHGHSQL 459 P+ +S+S N S ++ S+ + SS + K R ++ DTEE S +Q Sbjct: 614 PSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQE 673 Query: 460 DKRPE-PSTLENITDDKYAT----------VSSPSKSKKLECPSPAEQKP-----AEHVS 503 RP PS E + D + + ++S PSP + + A+ Sbjct: 674 ISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQM 733 Query: 504 LSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEPTTFGPTGVPAP-IPVLSVTQTLTTGPD 562 L P L +P +TPA S P P P+ T T VP P S P Sbjct: 734 LQAQPPALQAP-TGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT 792 Query: 563 SAVSQAHL----------TPSPVPVSIQAVNQPLMPLPQTLSLYQDPLYPGFPCNEKGDR 612 + V H+ PSP P + + PL PL + P + P + +G Sbjct: 793 APVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPP 852 Query: 613 AIVPPYSLCQTGEDLPKDKNILRFFFNLGVKAYSCPMWAPHSYLYPLHQAYLAAC----- 667 P+SL Q G L F P+ + YP L A Sbjct: 853 G---PHSL-QAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQ 908 Query: 668 -----RMYPKVPVPVY------PHNPWFQEAPAAQNESDCTCTDAHFPMQTEASVNGQMP 716 R P P P+ P + PA Q H + S+N +P Sbjct: 909 SQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKH----PPHLSGPSPFSMNANLP 964 Query: 717 QPEIGPPTFSSPLVIPPSQVSESHGQLSYQADLESETPGQLLHADYEESLSG-------- 768 P P S PPS QL Q+ +P Q ++L Sbjct: 965 PPPALKPLSSLSTHHPPS-AHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPT 1023 Query: 769 --KNMFPQPSFGPNPFL--GPVPIAPPFFP 794 + PQP F +PF+ GP PI PP P Sbjct: 1024 GLHQVAPQPPFAQHPFVPGGPPPITPPTCP 1053 Score = 35.8 bits (81), Expect = 0.22 Identities = 34/124 (27%), Positives = 53/124 (42%), Gaps = 8/124 (6%) Query: 848 PEARGEHVHSLPEASVSSKPDEGRTEQSSQTRKADTALASIPPVAEGKAHPPTQILNRER 907 P+ R ++ +S + P T SS KA+T S V E +A P + R+R Sbjct: 595 PDGRTSPINEDIRSSGRNSPSAAST--SSNDSKAETVKKSAKKVKE-EASSPLKSNKRQR 651 Query: 908 ETVPVELEPKRTIQSLKEKTEKVKDPKTAADVVSPGANSVDSRVQRPKEESSEDENEVSN 967 E V + E S K KT+++ P + ++ S DSR +E S D ++ Sbjct: 652 EKVASDTEEADRTSSKKTKTQEISRPNSPSE---GEGESSDSR--SVNDEGSSDPKDIDQ 706 Query: 968 ILRS 971 RS Sbjct: 707 DNRS 710 >gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 56.2 bits (134), Expect = 2e-07 Identities = 107/450 (23%), Positives = 152/450 (33%), Gaps = 71/450 (15%) Query: 406 PALSSSSVNQSASQ----SSNPCVQRKSSHVGDRKGSRRRM--DTEERKDKDSIHGHSQL 459 P+ +S+S N S ++ S+ + SS + K R ++ DTEE S +Q Sbjct: 614 PSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQE 673 Query: 460 DKRPE-PSTLENITDDKYAT----------VSSPSKSKKLECPSPAEQKP-----AEHVS 503 RP PS E + D + + ++S PSP + + A+ Sbjct: 674 ISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQM 733 Query: 504 LSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEPTTFGPTGVPAP-IPVLSVTQTLTTGPD 562 L P L +P +TPA S P P P+ T T VP P S P Sbjct: 734 LQAQPPALQAP-TGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT 792 Query: 563 SAVSQAHL----------TPSPVPVSIQAVNQPLMPLPQTLSLYQDPLYPGFPCNEKGDR 612 + V H+ PSP P + + PL PL + P + P + +G Sbjct: 793 APVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPP 852 Query: 613 AIVPPYSLCQTGEDLPKDKNILRFFFNLGVKAYSCPMWAPHSYLYPLHQAYLAAC----- 667 P+SL Q G L F P+ + YP L A Sbjct: 853 G---PHSL-QAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQ 908 Query: 668 -----RMYPKVPVPVY------PHNPWFQEAPAAQNESDCTCTDAHFPMQTEASVNGQMP 716 R P P P+ P + PA Q H + S+N +P Sbjct: 909 SQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKH----PPHLSGPSPFSMNANLP 964 Query: 717 QPEIGPPTFSSPLVIPPSQVSESHGQLSYQADLESETPGQLLHADYEESLSG-------- 768 P P S PPS QL Q+ +P Q ++L Sbjct: 965 PPPALKPLSSLSTHHPPS-AHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPT 1023 Query: 769 --KNMFPQPSFGPNPFL--GPVPIAPPFFP 794 + PQP F +PF+ GP PI PP P Sbjct: 1024 GLHQVAPQPPFAQHPFVPGGPPPITPPTCP 1053 Score = 35.8 bits (81), Expect = 0.22 Identities = 34/124 (27%), Positives = 53/124 (42%), Gaps = 8/124 (6%) Query: 848 PEARGEHVHSLPEASVSSKPDEGRTEQSSQTRKADTALASIPPVAEGKAHPPTQILNRER 907 P+ R ++ +S + P T SS KA+T S V E +A P + R+R Sbjct: 595 PDGRTSPINEDIRSSGRNSPSAAST--SSNDSKAETVKKSAKKVKE-EASSPLKSNKRQR 651 Query: 908 ETVPVELEPKRTIQSLKEKTEKVKDPKTAADVVSPGANSVDSRVQRPKEESSEDENEVSN 967 E V + E S K KT+++ P + ++ S DSR +E S D ++ Sbjct: 652 EKVASDTEEADRTSSKKTKTQEISRPNSPSE---GEGESSDSR--SVNDEGSSDPKDIDQ 706 Query: 968 ILRS 971 RS Sbjct: 707 DNRS 710 >gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 [Homo sapiens] Length = 559 Score = 51.6 bits (122), Expect = 4e-06 Identities = 67/287 (23%), Positives = 112/287 (39%), Gaps = 30/287 (10%) Query: 228 RLDHNGKFLNADVQGIHSENGPVLVEELGKKHTSKNLKAPPPESW---NTVSGKKMKKPS 284 R D K + +++ +++ +LG+ K KAPPP++ ++ K+ K S Sbjct: 206 RKDSESKSSSKELEREQAKSSKDTSRKLGEGRLPKEEKAPPPKAAFKEPKMALKETKLES 265 Query: 285 TSGQNFHSDVDYRGPKNPSKPIKAPSALPPRLQHPSGVRQHAFSSHSSGSQSQKFSSEHK 344 TS + P P P +A S P P + S S GS+S +S Sbjct: 266 TSPKG-------GPPPPPPPPPRASSKRPATADSPKPSAKKQKKSSSKGSRSAPGTSPRT 318 Query: 345 NLSRTPSQIIRKPDRERVEDFDHTSRESNYFGLSPEERREKQAIEESRLLYEIQNRDE-- 402 + S + S D++ +D T E P E ++ +EES E + E Sbjct: 319 SSSSSFS------DKKPAKDKSSTRGEKVKAESEPREAKKALEVEESNSEDEASFKSESA 372 Query: 403 QAFPALSSSSVNQSASQSSNPCVQRKSSHVGDRKGSRRRMDTEERKDKDSIHGHSQLDK- 461 Q+ P+ SSSS + S+ P ++ G + + +EE + DS G K Sbjct: 373 QSSPSNSSSSSDSSSDSDFEP---SQNHSQGPLRSMVEDLQSEESDEDDSSSGEEAAGKT 429 Query: 462 ---RPEPSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLS 505 R + + D A S PS+ P P ++ P + +S Sbjct: 430 NPGRDSRLSFSDSESDNSADSSLPSRE-----PPPPQKPPPPNSKVS 471 >gi|119943102 CREB binding protein isoform b [Homo sapiens] Length = 2404 Score = 50.1 bits (118), Expect = 1e-05 Identities = 47/160 (29%), Positives = 66/160 (41%), Gaps = 20/160 (12%) Query: 484 KSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEPTT----F 539 ++ +L CP P Q P + H TP P + PA P++P+T Sbjct: 801 QASQLPCP-PVTQSPLHPTPPPASTAAGMPSLQHTTP--PGMTPPQPAAPTQPSTPVSSS 857 Query: 540 GPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSP-VPVSIQAVNQPLMPLPQTLSLYQD 598 G T P P V S TQT +T A +QA +TP P PV +V P Q ++ Sbjct: 858 GQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQ 917 Query: 599 PLYPGFPCNEKG---DRAIVPPYSLC-------QTGEDLP 628 P PG P ++ D + P S+ Q G D+P Sbjct: 918 P--PGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVP 955 Score = 32.7 bits (73), Expect = 1.8 Identities = 64/292 (21%), Positives = 94/292 (32%), Gaps = 48/292 (16%) Query: 505 SNPAPLLVSPEVHLT-PAVPSLPATVPAWPS-EPTTFGPTGVPAPIPVLSVTQTLTTGPD 562 S P+P P P+ P P PA P P + P G P+ T T P Sbjct: 1843 SLPSPTSAPPGTPTQQPSTPQTPQP-PAQPQPSPVSMSPAGFPSVARTQPPTTVSTGKPT 1901 Query: 563 SAVSQAHLTPSPVPVSIQAVNQPLMPLPQTLSLYQDPLYPGFPCNEKGDRAIVPPYSLCQ 622 S V P P +++A Q Q LY+ + P G P + Sbjct: 1902 SQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTG--MGTPGSQMAP 1959 Query: 623 TGEDLPKDKNILRFFFNLGVKAYSCPMWAPHSYLYPLHQAYLAACRMYPKVPVPVYPHNP 682 ++P+ + S P+ +P P Sbjct: 1960 VSLNVPRPNQV------------SGPV-------------------------MPSMPPGQ 1982 Query: 683 WFQEAPAAQNESDCTCTDAHFPMQTEASVNGQMPQPEIGPPTFSSPLVIPP---SQVSES 739 W Q+AP Q + MQ +A+V G P + PP SP + + S S Sbjct: 1983 W-QQAPLPQQQPMPGLPRPVISMQAQAAVAGPR-MPSVQPPRSISPSALQDLLRTLKSPS 2040 Query: 740 HGQLSYQADLESETPGQLLHADYEESLSGKNMFPQPSFGPNPFLGPVPIAPP 791 Q Q ++ QL+ A + + + K + QP P P L P P Sbjct: 2041 SPQQQQQVLNILKSNPQLM-AAFIKQRTAKYVANQPGMQPQPGLQSQPGMQP 2091 Score = 32.0 bits (71), Expect = 3.1 Identities = 32/134 (23%), Positives = 46/134 (34%), Gaps = 16/134 (11%) Query: 679 PHNPWFQEAPAAQNESDCTCTDAHFPMQTEASVNGQMPQPEI--GPPTFSSPLVIPPSQV 736 P P + PA S + + A FP SV P + G PT P PP+Q Sbjct: 1859 PSTPQTPQPPAQPQPSPVSMSPAGFP-----SVARTQPPTTVSTGKPTSQVPAPPPPAQP 1913 Query: 737 SESHGQLSYQADLESETPGQLLHADYEESL---------SGKNMFPQPSFGPNPFLGPVP 787 + + + Q + E++ L + S+ G M P P P P Sbjct: 1914 PPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGP 1973 Query: 788 IAPPFFPHVWYGYP 801 + P P W P Sbjct: 1974 VMPSMPPGQWQQAP 1987 Score = 30.8 bits (68), Expect = 7.0 Identities = 27/101 (26%), Positives = 40/101 (39%), Gaps = 9/101 (8%) Query: 488 LECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEPTTFGPTG-VPA 546 L P+P + + + P + P+ L P VP P + T P G P Sbjct: 432 LSNPNPIDPSSMQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPM 491 Query: 547 PIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSIQAVNQPLM 587 IP + T P + +S+ S +P S+ A N PLM Sbjct: 492 NIPAGGI--TTDQQPPNLISE-----SALPTSLGATN-PLM 524 >gi|119943104 CREB binding protein isoform a [Homo sapiens] Length = 2442 Score = 50.1 bits (118), Expect = 1e-05 Identities = 47/160 (29%), Positives = 66/160 (41%), Gaps = 20/160 (12%) Query: 484 KSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEPTT----F 539 ++ +L CP P Q P + H TP P + PA P++P+T Sbjct: 839 QASQLPCP-PVTQSPLHPTPPPASTAAGMPSLQHTTP--PGMTPPQPAAPTQPSTPVSSS 895 Query: 540 GPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSP-VPVSIQAVNQPLMPLPQTLSLYQD 598 G T P P V S TQT +T A +QA +TP P PV +V P Q ++ Sbjct: 896 GQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQ 955 Query: 599 PLYPGFPCNEKG---DRAIVPPYSLC-------QTGEDLP 628 P PG P ++ D + P S+ Q G D+P Sbjct: 956 P--PGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVP 993 Score = 32.7 bits (73), Expect = 1.8 Identities = 64/292 (21%), Positives = 94/292 (32%), Gaps = 48/292 (16%) Query: 505 SNPAPLLVSPEVHLT-PAVPSLPATVPAWPS-EPTTFGPTGVPAPIPVLSVTQTLTTGPD 562 S P+P P P+ P P PA P P + P G P+ T T P Sbjct: 1881 SLPSPTSAPPGTPTQQPSTPQTPQP-PAQPQPSPVSMSPAGFPSVARTQPPTTVSTGKPT 1939 Query: 563 SAVSQAHLTPSPVPVSIQAVNQPLMPLPQTLSLYQDPLYPGFPCNEKGDRAIVPPYSLCQ 622 S V P P +++A Q Q LY+ + P G P + Sbjct: 1940 SQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTG--MGTPGSQMAP 1997 Query: 623 TGEDLPKDKNILRFFFNLGVKAYSCPMWAPHSYLYPLHQAYLAACRMYPKVPVPVYPHNP 682 ++P+ + S P+ +P P Sbjct: 1998 VSLNVPRPNQV------------SGPV-------------------------MPSMPPGQ 2020 Query: 683 WFQEAPAAQNESDCTCTDAHFPMQTEASVNGQMPQPEIGPPTFSSPLVIPP---SQVSES 739 W Q+AP Q + MQ +A+V G P + PP SP + + S S Sbjct: 2021 W-QQAPLPQQQPMPGLPRPVISMQAQAAVAGPR-MPSVQPPRSISPSALQDLLRTLKSPS 2078 Query: 740 HGQLSYQADLESETPGQLLHADYEESLSGKNMFPQPSFGPNPFLGPVPIAPP 791 Q Q ++ QL+ A + + + K + QP P P L P P Sbjct: 2079 SPQQQQQVLNILKSNPQLM-AAFIKQRTAKYVANQPGMQPQPGLQSQPGMQP 2129 Score = 32.3 bits (72), Expect = 2.4 Identities = 33/133 (24%), Positives = 52/133 (39%), Gaps = 13/133 (9%) Query: 460 DKRPEPSTLENITDDKYATVSSPSKSKK----LECPSPAEQKPAEHVSLSNPAPLLVSPE 515 DKR + + L + T+ S ++ L P+P + + + P + P+ Sbjct: 438 DKRNQQTILGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSSMQRAYAALGLPYMNQPQ 497 Query: 516 VHLTPAVPSLPATVPAWPSEPTTFGPTG-VPAPIPVLSVTQTLTTGPDSAVSQAHLTPSP 574 L P VP P + T P G P IP + T P + +S+ S Sbjct: 498 TQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGI--TTDQQPPNLISE-----SA 550 Query: 575 VPVSIQAVNQPLM 587 +P S+ A N PLM Sbjct: 551 LPTSLGATN-PLM 562 Score = 32.0 bits (71), Expect = 3.1 Identities = 32/134 (23%), Positives = 46/134 (34%), Gaps = 16/134 (11%) Query: 679 PHNPWFQEAPAAQNESDCTCTDAHFPMQTEASVNGQMPQPEI--GPPTFSSPLVIPPSQV 736 P P + PA S + + A FP SV P + G PT P PP+Q Sbjct: 1897 PSTPQTPQPPAQPQPSPVSMSPAGFP-----SVARTQPPTTVSTGKPTSQVPAPPPPAQP 1951 Query: 737 SESHGQLSYQADLESETPGQLLHADYEESL---------SGKNMFPQPSFGPNPFLGPVP 787 + + + Q + E++ L + S+ G M P P P P Sbjct: 1952 PPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGP 2011 Query: 788 IAPPFFPHVWYGYP 801 + P P W P Sbjct: 2012 VMPSMPPGQWQQAP 2025 >gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] Length = 2752 Score = 50.1 bits (118), Expect = 1e-05 Identities = 58/288 (20%), Positives = 109/288 (37%), Gaps = 14/288 (4%) Query: 299 PKNPSKPIKAPSALPPRLQHPSGVRQHAFSSHSSGSQSQKFSSE---HKNLSRTPSQIIR 355 P+ ++ K P+ PP+ S VR+ + S + Q +K + ++ S +P + + Sbjct: 153 PQRRAREAKQPAPEPPKPY--SLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERK 210 Query: 356 KPDRERVEDFDHTSRESNYFGLSPEERRE----KQAIEESRLLYEIQNRDEQAFPALSSS 411 K +++ + S++ + +P+ +R+ K+ S R ++ A S+S Sbjct: 211 KSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSAS 270 Query: 412 SVNQSASQSSNPCVQRKSSHVGDRKGSRRRMDTEERKDKDSIHGHSQLDKRPEPSTLENI 471 S + S S+S + + ++ + R S E S G + + P T Sbjct: 271 SSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQ 330 Query: 472 TDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLV-----SPEVHLTPAVPSLP 526 Y K K PSP+ ++ + P PLL SP+ T + P Sbjct: 331 PSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEP 390 Query: 527 ATVPAWPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSP 574 P+ S P P +P S +++ P H + SP Sbjct: 391 VNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSP 438 Score = 41.6 bits (96), Expect = 0.004 Identities = 59/254 (23%), Positives = 94/254 (37%), Gaps = 41/254 (16%) Query: 291 HSDVDYRGPKNPSKPIKAPSALPPRLQHPSGVRQHAFSSHSSGSQSQKFSSEHKNLSRTP 350 HSDV ++ A +AL P + S + SS SS S S SS S + Sbjct: 2503 HSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSD 2562 Query: 351 SQIIRKPDR-----ERVEDFDHTSRESNYFGLSPEERREKQAIEESRLLYEIQNRDEQAF 405 S+ P + +RV +E+ G PE K+ S + + Sbjct: 2563 SEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSS 2622 Query: 406 PALSSSSVNQSASQSSNPCVQRKSSH---------------------VGDRKGSRRRMDT 444 + SSSS + S+S SS+ SS G+R+ R Sbjct: 2623 SSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPI 2682 Query: 445 EERKDKDSIHGHSQLDKR---PEPSTLENITDD--------KYATVSSPSKSKKLECPSP 493 + +D S+ +S +++R P+PS + + + SPS ++ E PSP Sbjct: 2683 DSLRDSRSL-SYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSP 2741 Query: 494 AEQKPAEHVSLSNP 507 +P H S +P Sbjct: 2742 ---RPMRHRSSRSP 2752 Score = 40.8 bits (94), Expect = 0.007 Identities = 72/305 (23%), Positives = 120/305 (39%), Gaps = 42/305 (13%) Query: 245 SENGPVLVEELGKKHTSKNLKAPPPESWNTVSGKKMKKPSTSGQNFHSDVDYRGPKNPSK 304 S + P + + S++L +P ++ + +S ++ S+ S R ++ S Sbjct: 743 SNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSS 802 Query: 305 PIKAPSALPPRLQHPSGVRQHAFSSHSSGSQSQKFSSEH-KNLSRTPSQIIRKPDRERVE 363 KA S PPR S S + QS SS H K S TP P + + Sbjct: 803 QPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTP------PRQGSI- 855 Query: 364 DFDHTSRESNYFGLSPEERREKQAIEESRLLYEIQNRDE---QAFPALSSSS-VNQSASQ 419 TS ++N ++P+ R ++ + L +R + P + SS+ QS S+ Sbjct: 856 ----TSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSR 911 Query: 420 SSNP-------CVQRKSSHVGDRKGSRRRMD--TEERKDKDSIHGHSQLDKRPEPSTLEN 470 SS+P R+ SH G S R+ T R+ + S+ S ++ R P Sbjct: 912 SSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSR-SVSPCSNVESRLLP----- 965 Query: 471 ITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAVPSLPATVP 530 +Y+ S S K++ +P Q H +P P + + TP PSL + Sbjct: 966 ----RYSHSGSSSPDTKVKPETPPRQ---SHSGSISPYPKVKAQ----TPPGPSLSGSKS 1014 Query: 531 AWPSE 535 P E Sbjct: 1015 PCPQE 1019 Score = 38.9 bits (89), Expect = 0.026 Identities = 65/306 (21%), Positives = 107/306 (34%), Gaps = 47/306 (15%) Query: 297 RGPKNPSKPIKAPSA--LPPRLQHPSGVRQHAFSSHS----------SGSQS-------- 336 R P S+ +APS LPP P AFS S +GSQS Sbjct: 2423 RAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVAT 2482 Query: 337 -QKFSSEHKNLSRTPSQIIRKPDRERVEDFDHTSRESNYFGLSPEERREKQAIEESRLLY 395 + +H + P+ + D + S L P + R + S Sbjct: 2483 TTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSS---- 2538 Query: 396 EIQNRDEQAFPALSSSSVNQSASQSSNPCVQRKSSHVGDRKGSRRRMDTEERKDKDSIHG 455 + + SSSS + S+S S+ SS + + +R+ + K+++ Sbjct: 2539 ------SSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVRE 2592 Query: 456 HSQLDKRP-----EPSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPL 510 + P S+ + + ++ SS S S S + + S S+P+P Sbjct: 2593 GRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPA 2652 Query: 511 LVSPEVHLTPAVPSLPATVPAWPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHL 570 P+ PA P P P E + P PI L +++L+ P V + Sbjct: 2653 KPGPQALPKPASPKKPP-----PGERRSRSPR---KPIDSLRDSRSLSYSP---VERRRP 2701 Query: 571 TPSPVP 576 +P P P Sbjct: 2702 SPQPSP 2707 Score = 35.8 bits (81), Expect = 0.22 Identities = 65/306 (21%), Positives = 114/306 (37%), Gaps = 34/306 (11%) Query: 300 KNPSKPIKAPSALPPRLQHPSGVRQHAFSSHSSGSQSQKFSSEHKNL-------SRTPSQ 352 + P++ ++ S P R S R A S ++ S ++L SRTP + Sbjct: 661 RTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQR 720 Query: 353 IIRKPDRERVEDFDHTSRESNYFGLSPEERREKQAIEESRLLYEIQNRDEQAFPALSSSS 412 R ++ TS+ + SPE ++ + + SR L +++ A S S Sbjct: 721 RGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSK------AKSRLS 774 Query: 413 VNQSASQSSNPCVQRKS------SHVGDRKGSRRRMDTEERKDKDSIHGHSQLDKRPEPS 466 + +S S SS PC ++KS S G + + R S Q K P Sbjct: 775 LRRSLSGSS-PCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQ 833 Query: 467 TLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAVPSLP 526 + + + +P + + P EQ V+ + SP+ L PS Sbjct: 834 SHSSSSPHPKVKSGTPPRQGSITSPQANEQS----VTPQRRSCFESSPDPELKSRTPSRH 889 Query: 527 ATVPAWP-----SEPTTFGPTGVPAPIP----VLSVTQTLTTGPDSAVSQAHLTPSPVPV 577 + + P S P P+ +P P ++S Q +G S+ S + +T P Sbjct: 890 SCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSG-SSSPSPSRVTSRTTPR 948 Query: 578 SIQAVN 583 ++V+ Sbjct: 949 RSRSVS 954 Score = 33.5 bits (75), Expect = 1.1 Identities = 73/319 (22%), Positives = 114/319 (35%), Gaps = 49/319 (15%) Query: 216 GLQYEVGDKCQVRLDHNGKFLNADVQGIHSENGPVL-VEELGKK---HTSKNLKAPPPES 271 G + G +V+ D NG FLN E P L ++E + H+S L E Sbjct: 1340 GTEMNTGFSSEVKEDLNGPFLN------QLETDPSLDMKEQSTRSSGHSSSELSPDAVE- 1392 Query: 272 WNTVSGKKMKKPSTSGQNFHSDVDYRGPKNPSKPIKAPSALPPRLQH--PSGVRQHAFSS 329 K +S Q+ S V P+ PS+ ++ SA P ++ P + + S Sbjct: 1393 ---------KAGMSSNQSISSPVLDAVPRTPSRE-RSSSASSPEMKDGLPRTPSRRSRSG 1442 Query: 330 HSSGSQSQKFSSEHKNLSRTP---SQIIRKPDRERVEDFDHTSRESNYFGLSPEERREKQ 386 S G + + +LS + I R P R R E +S E +P R Sbjct: 1443 SSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSE--CDSSPEPKALPQTPRPRSRSP 1500 Query: 387 AIEESRLLYEIQNRDEQAFPALSSSSVNQSASQSSNPCVQRKSSHVGDRKGSRRRMDTEE 446 + E R+ S SSV+Q + + P QR S + +E Sbjct: 1501 SSPELNNKCLTPQRERSG----SESSVDQK-TVARTPLGQRSRSGSSQELDVKPSASPQE 1555 Query: 447 RKDKDS-----------IHGHSQLDKRPEPSTLENITDDKYATVSSPSKSKKLECPSPAE 495 R + DS + S+ PE + ++ + + SSP K P Sbjct: 1556 RSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDK-----PRA 1610 Query: 496 QKPAEHVSLSNPAPLLVSP 514 A+ S S+P P +P Sbjct: 1611 APRAQSGSDSSPEPKAPAP 1629 >gi|187829452 autism susceptibility candidate 2 isoform 2 [Homo sapiens] Length = 1235 Score = 48.9 bits (115), Expect = 2e-05 Identities = 82/343 (23%), Positives = 127/343 (37%), Gaps = 52/343 (15%) Query: 270 ESWNTVSGKKMKKPSTSGQNFHSDVD-------YRGPKNPSKPIKAPSALPPRLQHPSGV 322 E T KK ++ T+G +FHS Y + + + L R + P + Sbjct: 115 EKRQTPLTKKKREALTNGLSFHSKKSRLSHPHHYSSDRENDRNLC--QHLGKRKKMPKAL 172 Query: 323 RQHAFSSHSS-GSQSQKFSSEHKNLSRTPSQIIRKPDRERVEDFDH-TSRESNYFGLSPE 380 RQ +S S S+ S E K R+ S RER+ D +S + YF S Sbjct: 173 RQLKPGQNSCRDSDSESASGESKGFHRSSS-------RERLSDSSAPSSLGTGYFCDSDS 225 Query: 381 ERREKQAIEESRLLYE--IQNRDEQAFPALSSSSVNQSASQSSNPCVQRKSSHVGDRKGS 438 ++ EK + S L+ I N+D P L ++ + SQ + P V + S Sbjct: 226 DQEEKASDASSEKLFNTVIVNKD----PELGVGTLPEHDSQDAGPIVPKISG-------- 273 Query: 439 RRRMDTEERKDKDSIHGHSQLDKRP--EPSTLENITDDKYATVSSPSKSKKLECPSPAEQ 496 ++ + K +D K P EP L++ + P +L PSP Sbjct: 274 ---LERSQEKSQDCC-------KEPIFEPVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPD 323 Query: 497 KPAEHVSLSNPAPLLVS-----PEVHLTPAVPSLPATVPAWPSEPTTFGPTGVPAPIPVL 551 + P PL PE L PA P P P PT +P P+ Sbjct: 324 LVQRTEAPPQPPPLSTQPPQGPPEAQLQPA-PQPQVQRPPRPQSPTQLLHQNLP-PVQAH 381 Query: 552 SVTQTLTTGPDSAVSQAHLTPSPVPVSIQAVNQPLMPLPQTLS 594 Q+L+ P SA + + L+ + + S + P P +S Sbjct: 382 PSAQSLSQ-PLSAYNSSSLSLNSLSSSRSSTPAKTQPAPPHIS 423 Score = 30.8 bits (68), Expect = 7.0 Identities = 34/153 (22%), Positives = 57/153 (37%), Gaps = 13/153 (8%) Query: 253 EELGKKHTSKNLKAPPPESWNTVSGKKMKKPSTSGQNFHSDVDYRGPKNPSKPIKAPSAL 312 E + K+H+S P P V+ + ST H + + R P + + S Sbjct: 821 ESVEKRHSSH----PSPAPVLPVNALGHTRSSTEQIRAHLNTEAREKDKPKERERDHSES 876 Query: 313 PPRL--QHPSGVRQHAFSSHSSGSQSQKFSSEHKNLSRTPSQIIRKPDRERVEDFDHTSR 370 L H G + + E K L+R PS +R P E +SR Sbjct: 877 RKDLAADEHKAKEGHLPEKDGHGHEGRAAGEEAKQLARVPSPYVRTPVVESARPNSTSSR 936 Query: 371 ESNYFGLSPEERREKQAIEESRLLYEIQNRDEQ 403 E+ E R+ + A E + E++ ++E+ Sbjct: 937 EA-------EPRKGEPAYENPKKSSEVKVKEER 962 >gi|17864090 autism susceptibility candidate 2 isoform 1 [Homo sapiens] Length = 1259 Score = 48.9 bits (115), Expect = 2e-05 Identities = 82/343 (23%), Positives = 127/343 (37%), Gaps = 52/343 (15%) Query: 270 ESWNTVSGKKMKKPSTSGQNFHSDVD-------YRGPKNPSKPIKAPSALPPRLQHPSGV 322 E T KK ++ T+G +FHS Y + + + L R + P + Sbjct: 115 EKRQTPLTKKKREALTNGLSFHSKKSRLSHPHHYSSDRENDRNLC--QHLGKRKKMPKAL 172 Query: 323 RQHAFSSHSS-GSQSQKFSSEHKNLSRTPSQIIRKPDRERVEDFDH-TSRESNYFGLSPE 380 RQ +S S S+ S E K R+ S RER+ D +S + YF S Sbjct: 173 RQLKPGQNSCRDSDSESASGESKGFHRSSS-------RERLSDSSAPSSLGTGYFCDSDS 225 Query: 381 ERREKQAIEESRLLYE--IQNRDEQAFPALSSSSVNQSASQSSNPCVQRKSSHVGDRKGS 438 ++ EK + S L+ I N+D P L ++ + SQ + P V + S Sbjct: 226 DQEEKASDASSEKLFNTVIVNKD----PELGVGTLPEHDSQDAGPIVPKISG-------- 273 Query: 439 RRRMDTEERKDKDSIHGHSQLDKRP--EPSTLENITDDKYATVSSPSKSKKLECPSPAEQ 496 ++ + K +D K P EP L++ + P +L PSP Sbjct: 274 ---LERSQEKSQDCC-------KEPIFEPVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPD 323 Query: 497 KPAEHVSLSNPAPLLVS-----PEVHLTPAVPSLPATVPAWPSEPTTFGPTGVPAPIPVL 551 + P PL PE L PA P P P PT +P P+ Sbjct: 324 LVQRTEAPPQPPPLSTQPPQGPPEAQLQPA-PQPQVQRPPRPQSPTQLLHQNLP-PVQAH 381 Query: 552 SVTQTLTTGPDSAVSQAHLTPSPVPVSIQAVNQPLMPLPQTLS 594 Q+L+ P SA + + L+ + + S + P P +S Sbjct: 382 PSAQSLSQ-PLSAYNSSSLSLNSLSSSRSSTPAKTQPAPPHIS 423 Score = 30.8 bits (68), Expect = 7.0 Identities = 34/153 (22%), Positives = 57/153 (37%), Gaps = 13/153 (8%) Query: 253 EELGKKHTSKNLKAPPPESWNTVSGKKMKKPSTSGQNFHSDVDYRGPKNPSKPIKAPSAL 312 E + K+H+S P P V+ + ST H + + R P + + S Sbjct: 845 ESVEKRHSSH----PSPAPVLPVNALGHTRSSTEQIRAHLNTEAREKDKPKERERDHSES 900 Query: 313 PPRL--QHPSGVRQHAFSSHSSGSQSQKFSSEHKNLSRTPSQIIRKPDRERVEDFDHTSR 370 L H G + + E K L+R PS +R P E +SR Sbjct: 901 RKDLAADEHKAKEGHLPEKDGHGHEGRAAGEEAKQLARVPSPYVRTPVVESARPNSTSSR 960 Query: 371 ESNYFGLSPEERREKQAIEESRLLYEIQNRDEQ 403 E+ E R+ + A E + E++ ++E+ Sbjct: 961 EA-------EPRKGEPAYENPKKSSEVKVKEER 986 >gi|209862789 microtubule associated monoxygenase, calponin and LIM domain containing 3 isoform 1 [Homo sapiens] Length = 2002 Score = 47.0 bits (110), Expect = 9e-05 Identities = 75/344 (21%), Positives = 124/344 (36%), Gaps = 56/344 (16%) Query: 320 SGVRQHAFSSHSSGSQSQKFSSEHKNLSRTPSQIIRKPDRERVE-------DFDHTSRES 372 +G + SS S ++ E + PS + P +E V + S Sbjct: 925 TGAEEDVASSSSESEMEEEGEEEEEEPRLPPSDLGGVPWKEAVRIHALLKGKSEEELEAS 984 Query: 373 NYFGLSPEERREKQAIEESRLLYEIQNRDEQAFPALSSSSVNQSASQ---SSNPCVQRKS 429 FG EE E++ E + +E+ SS + NQ Q +++P + Sbjct: 985 KSFGPGNEEEEEEEEEYEEEEEEDYDEEEEE-----SSEAGNQRLQQVMHAADPLEIQAD 1039 Query: 430 ---SHVGDRKGSRRRMDTEE-------------RKDKDS----IHGHSQLDKRPEPSTLE 469 +H+ +R+ R E +D DS I G + D P + E Sbjct: 1040 VHWTHIREREEEERMAPASESSASGAPLDENDLEEDVDSEPAEIEGEAAEDGDPGDTGAE 1099 Query: 470 NITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLT--PAVPSLPA 527 + DD++ + S ++L P PAE + + +S L + H P+ + P Sbjct: 1100 -LDDDQHWSDSPSDADRELRLPCPAEGEAELELRVSEDEEKLPASPKHQERGPSQATSPI 1158 Query: 528 TVPAWPS-------EPTTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTP-----SPV 575 P + P+T GP P P T P+ + L P + Sbjct: 1159 RSPQESALLFIPVHSPSTEGPQLPPVP------AATQEKSPEERLFPEPLLPKEKPKADA 1212 Query: 576 PVSIQAVNQPLMPLPQTLSLYQDPLYPGFPCNEKGDRAIVPPYS 619 P ++AV+ P+ P TL + P+ PG P + A PP S Sbjct: 1213 PSDLKAVHSPIRSQPVTLPEARTPVSPGSPQPQPPVAASTPPPS 1256 Score = 33.5 bits (75), Expect = 1.1 Identities = 28/105 (26%), Positives = 42/105 (40%), Gaps = 13/105 (12%) Query: 486 KKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEPTTFGPTGVP 545 +K + +P++ K S P L PE TP P P +P T P Sbjct: 1206 EKPKADAPSDLKAVHSPIRSQPVTL---PEAR-TPVSPGSPQP------QPPVAASTPPP 1255 Query: 546 APIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSIQAVNQPLMPLP 590 +P+P+ S Q T + +Q+ + P P + PL PLP Sbjct: 1256 SPLPICSQPQPSTEATVPSPTQSPIRFQPAPAK---TSTPLAPLP 1297 >gi|189181720 proteoglycan 4 isoform B [Homo sapiens] Length = 1363 Score = 46.2 bits (108), Expect = 2e-04 Identities = 77/345 (22%), Positives = 122/345 (35%), Gaps = 32/345 (9%) Query: 276 SGKKMKKPSTSGQNFHSDVDYRGPKNPSKPI--KAPSALPPRLQHPSGVRQHAFSSHSSG 333 S KK PS + Q S R PK P+K K + +H Q + SS SS Sbjct: 74 SSKKAPPPSGASQTIKSTTK-RSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSS 132 Query: 334 SQSQKF----SSEHKNLSRTPSQIIRKPDRER------------VEDFDHTSRESNYFGL 377 S S SS++ +R + ++ D ++ V D + ++ F + Sbjct: 133 SSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKV 192 Query: 378 SPEERREKQAIEES---RLLYEIQNRDEQAFPALSSSSVNQSASQSSNPCVQRKSSHVGD 434 + + Q + S ++ + P S +S S + + V+ K + + Sbjct: 193 TTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTN 252 Query: 435 RKGSRRRMD-TEERKDKDSIHGHSQLDKRPEPSTLENITDDKYATVSSPSKSKKLECPSP 493 ++ S + T K+ SI S D P L T T P+ + E P+P Sbjct: 253 KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKE-PTP 311 Query: 494 AEQKPAEHVSLSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEPTTFGPTGV--PAPIPVL 551 K + P P + TP P+ P T + P+ P PT PAP Sbjct: 312 TTPKEPASTTPKEPTPTTIK-SAPTTPKEPA-PTTTKSAPTTPKEPAPTTTKEPAPTTPK 369 Query: 552 SVTQTLTTGPDSAVSQAHLT----PSPVPVSIQAVNQPLMPLPQT 592 T T P +++ T P+P A P P P T Sbjct: 370 EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTT 414 Score = 37.4 bits (85), Expect = 0.075 Identities = 74/365 (20%), Positives = 133/365 (36%), Gaps = 31/365 (8%) Query: 253 EELGKKHT-SKNLKAPPPESWNTVSG--KKMKKPSTSGQNFHSDVDYRGPKNP-SKPIKA 308 EE+ ++H+ S+N ++ S ++ S +K+K S N + N ++ K Sbjct: 111 EEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKK 170 Query: 309 PSALPPRLQHP-SGVRQHAFSSHSSGSQSQKFSSEHKNLSRTPSQIIRKP--DRERVEDF 365 P+ PP + SG+ F + + + ++H +S +P KP R + Sbjct: 171 PTPKPPVVDEAGSGLDNGDFKVTTPDTST----TQHNKVSTSPKITTAKPINPRPSLPPN 226 Query: 366 DHTSRESNYFGLSPEERREKQAIEESRLLYEIQNRDEQAFPALSSSSVNQSASQSSNPC- 424 TS+E++ ++ E E + + + E+ A + S+ +++++ P Sbjct: 227 SDTSKETS-LTVNKETTVETKETTTTNKQTSTDGK-EKTTSAKETQSIEKTSAKDLAPTS 284 Query: 425 -VQRKSSHVGDRKGSRRRMDT-EERKDKDSIHGHSQLDKRPEPSTLENI--TDDKYATVS 480 V K + + + T +E S K P P+T+++ T + A + Sbjct: 285 KVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTT 344 Query: 481 SPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLT------------PAVPSLPA- 527 + S + P+P K + PAP T P P PA Sbjct: 345 TKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAP 404 Query: 528 TVPAWPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSIQAVNQPLM 587 T P P+ T PT P + + T P A P+P A P Sbjct: 405 TTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKE 464 Query: 588 PLPQT 592 P P T Sbjct: 465 PAPTT 469 Score = 35.4 bits (80), Expect = 0.28 Identities = 33/133 (24%), Positives = 41/133 (30%), Gaps = 2/133 (1%) Query: 461 KRPEPSTLENI-TDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLT 519 K P P+T E T K ++P K PA P E + P +P+ Sbjct: 424 KEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP 483 Query: 520 PAVPSLPATVPAWPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSI 579 S P T T PT P P + TT P P+P Sbjct: 484 TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT-PKEPAPTTPKKPAPTTPKE 542 Query: 580 QAVNQPLMPLPQT 592 A P P P T Sbjct: 543 PAPTTPKEPAPTT 555 Score = 35.4 bits (80), Expect = 0.28 Identities = 33/132 (25%), Positives = 45/132 (34%), Gaps = 21/132 (15%) Query: 461 KRPEPSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTP 520 K P P+T + +P+ K+ +P E P L+ P ++P P Sbjct: 549 KEPAPTTTKK---------PAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKP 599 Query: 521 AVPSLPATVPAWPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSIQ 580 A + P P EPT PT P P T P +A P+P Sbjct: 600 APTTPEELAPTTPEEPT---PTTPEEPAP---------TTPKAAAPNTPKEPAPTTPKEP 647 Query: 581 AVNQPLMPLPQT 592 A P P P T Sbjct: 648 APTTPKEPAPTT 659 Score = 34.7 bits (78), Expect = 0.48 Identities = 34/139 (24%), Positives = 47/139 (33%), Gaps = 14/139 (10%) Query: 461 KRPEPSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTP 520 ++P P+T E + T P+ + E P+P K A + PAP TP Sbjct: 597 EKPAPTTPEELAP---TTPEEPTPTTPEE-PAPTTPKAAAPNTPKEPAPTTPKEPAPTTP 652 Query: 521 AVPSLPATVPAWPSEPTTFGPTGVPAPIPVL-------SVTQTLTTGPDSAVSQAHLTPS 573 P+ P+ P PT + P P + T T P S P+ Sbjct: 653 KEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD---KPA 709 Query: 574 PVPVSIQAVNQPLMPLPQT 592 P A P P P T Sbjct: 710 PTTPKGTAPTTPKEPAPTT 728 Score = 34.3 bits (77), Expect = 0.63 Identities = 37/135 (27%), Positives = 51/135 (37%), Gaps = 13/135 (9%) Query: 461 KRPEPSTLENI--TDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHL 518 K P P+T ++ T + A ++ S + PSP K + PAP Sbjct: 479 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 538 Query: 519 TPAVPSLPATVPAWPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSA-VSQAHLTPSPVPV 577 TP P+ P P EP PT P P TT ++A + LTP+ P Sbjct: 539 TPKEPA-----PTTPKEPA---PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPT-TPE 589 Query: 578 SIQAVNQPLMPLPQT 592 + A P P P T Sbjct: 590 KL-APTTPEKPAPTT 603 Score = 33.9 bits (76), Expect = 0.83 Identities = 35/139 (25%), Positives = 45/139 (32%), Gaps = 17/139 (12%) Query: 461 KRPEPSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTP 520 K P+TL K ++P K E +P K + PAP TP Sbjct: 669 KGTAPTTL------KEPAPTTPKKPAPKEL-APTTTKEPTSTTCDKPAPTTPKGTAPTTP 721 Query: 521 AVPSLPATVPAWPSEPTTFGPTGVPAPIPVL-------SVTQTLTTGPDSAVSQAHLTPS 573 P+ P+ P PT + P P + T T GP S S P+ Sbjct: 722 KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD---KPA 778 Query: 574 PVPVSIQAVNQPLMPLPQT 592 P A P P P T Sbjct: 779 PTTPKETAPTTPKEPAPTT 797 Score = 30.8 bits (68), Expect = 7.0 Identities = 31/135 (22%), Positives = 49/135 (36%), Gaps = 5/135 (3%) Query: 461 KRPEPSTLENI--TDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHL 518 K P P+T + T K ++P K E +P K + PAP Sbjct: 730 KEPAPTTPKGTAPTTLKEPAPTTPKKPAPKEL-APTTTKGPTSTTSDKPAPTTPKETAPT 788 Query: 519 TPAVPSLPATVPAWPSEPTTFGPTGVPAPIPVLS-VTQTLTTGPDSAVSQAHLTPSPVPV 577 TP P+ P+ P T PT P + T+ PD + + P+P + Sbjct: 789 TPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKAL 848 Query: 578 SIQAVNQPLMPLPQT 592 + +P +P +T Sbjct: 849 E-NSPKEPGVPTTKT 862 >gi|67190163 proteoglycan 4 isoform A [Homo sapiens] Length = 1404 Score = 46.2 bits (108), Expect = 2e-04 Identities = 77/345 (22%), Positives = 122/345 (35%), Gaps = 32/345 (9%) Query: 276 SGKKMKKPSTSGQNFHSDVDYRGPKNPSKPI--KAPSALPPRLQHPSGVRQHAFSSHSSG 333 S KK PS + Q S R PK P+K K + +H Q + SS SS Sbjct: 115 SSKKAPPPSGASQTIKSTTK-RSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSS 173 Query: 334 SQSQKF----SSEHKNLSRTPSQIIRKPDRER------------VEDFDHTSRESNYFGL 377 S S SS++ +R + ++ D ++ V D + ++ F + Sbjct: 174 SSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKV 233 Query: 378 SPEERREKQAIEES---RLLYEIQNRDEQAFPALSSSSVNQSASQSSNPCVQRKSSHVGD 434 + + Q + S ++ + P S +S S + + V+ K + + Sbjct: 234 TTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTN 293 Query: 435 RKGSRRRMD-TEERKDKDSIHGHSQLDKRPEPSTLENITDDKYATVSSPSKSKKLECPSP 493 ++ S + T K+ SI S D P L T T P+ + E P+P Sbjct: 294 KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKE-PTP 352 Query: 494 AEQKPAEHVSLSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEPTTFGPTGV--PAPIPVL 551 K + P P + TP P+ P T + P+ P PT PAP Sbjct: 353 TTPKEPASTTPKEPTPTTIK-SAPTTPKEPA-PTTTKSAPTTPKEPAPTTTKEPAPTTPK 410 Query: 552 SVTQTLTTGPDSAVSQAHLT----PSPVPVSIQAVNQPLMPLPQT 592 T T P +++ T P+P A P P P T Sbjct: 411 EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTT 455 Score = 37.4 bits (85), Expect = 0.075 Identities = 74/365 (20%), Positives = 133/365 (36%), Gaps = 31/365 (8%) Query: 253 EELGKKHT-SKNLKAPPPESWNTVSG--KKMKKPSTSGQNFHSDVDYRGPKNP-SKPIKA 308 EE+ ++H+ S+N ++ S ++ S +K+K S N + N ++ K Sbjct: 152 EEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKK 211 Query: 309 PSALPPRLQHP-SGVRQHAFSSHSSGSQSQKFSSEHKNLSRTPSQIIRKP--DRERVEDF 365 P+ PP + SG+ F + + + ++H +S +P KP R + Sbjct: 212 PTPKPPVVDEAGSGLDNGDFKVTTPDTST----TQHNKVSTSPKITTAKPINPRPSLPPN 267 Query: 366 DHTSRESNYFGLSPEERREKQAIEESRLLYEIQNRDEQAFPALSSSSVNQSASQSSNPC- 424 TS+E++ ++ E E + + + E+ A + S+ +++++ P Sbjct: 268 SDTSKETS-LTVNKETTVETKETTTTNKQTSTDGK-EKTTSAKETQSIEKTSAKDLAPTS 325 Query: 425 -VQRKSSHVGDRKGSRRRMDT-EERKDKDSIHGHSQLDKRPEPSTLENI--TDDKYATVS 480 V K + + + T +E S K P P+T+++ T + A + Sbjct: 326 KVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTT 385 Query: 481 SPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLT------------PAVPSLPA- 527 + S + P+P K + PAP T P P PA Sbjct: 386 TKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAP 445 Query: 528 TVPAWPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSIQAVNQPLM 587 T P P+ T PT P + + T P A P+P A P Sbjct: 446 TTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKE 505 Query: 588 PLPQT 592 P P T Sbjct: 506 PAPTT 510 Score = 35.4 bits (80), Expect = 0.28 Identities = 33/133 (24%), Positives = 41/133 (30%), Gaps = 2/133 (1%) Query: 461 KRPEPSTLENI-TDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLT 519 K P P+T E T K ++P K PA P E + P +P+ Sbjct: 465 KEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP 524 Query: 520 PAVPSLPATVPAWPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSI 579 S P T T PT P P + TT P P+P Sbjct: 525 TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT-PKEPAPTTPKKPAPTTPKE 583 Query: 580 QAVNQPLMPLPQT 592 A P P P T Sbjct: 584 PAPTTPKEPAPTT 596 Score = 35.4 bits (80), Expect = 0.28 Identities = 33/132 (25%), Positives = 45/132 (34%), Gaps = 21/132 (15%) Query: 461 KRPEPSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTP 520 K P P+T + +P+ K+ +P E P L+ P ++P P Sbjct: 590 KEPAPTTTKK---------PAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKP 640 Query: 521 AVPSLPATVPAWPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSIQ 580 A + P P EPT PT P P T P +A P+P Sbjct: 641 APTTPEELAPTTPEEPT---PTTPEEPAP---------TTPKAAAPNTPKEPAPTTPKEP 688 Query: 581 AVNQPLMPLPQT 592 A P P P T Sbjct: 689 APTTPKEPAPTT 700 Score = 34.7 bits (78), Expect = 0.48 Identities = 34/139 (24%), Positives = 47/139 (33%), Gaps = 14/139 (10%) Query: 461 KRPEPSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTP 520 ++P P+T E + T P+ + E P+P K A + PAP TP Sbjct: 638 EKPAPTTPEELAP---TTPEEPTPTTPEE-PAPTTPKAAAPNTPKEPAPTTPKEPAPTTP 693 Query: 521 AVPSLPATVPAWPSEPTTFGPTGVPAPIPVL-------SVTQTLTTGPDSAVSQAHLTPS 573 P+ P+ P PT + P P + T T P S P+ Sbjct: 694 KEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD---KPA 750 Query: 574 PVPVSIQAVNQPLMPLPQT 592 P A P P P T Sbjct: 751 PTTPKGTAPTTPKEPAPTT 769 Score = 34.3 bits (77), Expect = 0.63 Identities = 37/135 (27%), Positives = 51/135 (37%), Gaps = 13/135 (9%) Query: 461 KRPEPSTLENI--TDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHL 518 K P P+T ++ T + A ++ S + PSP K + PAP Sbjct: 520 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 579 Query: 519 TPAVPSLPATVPAWPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSA-VSQAHLTPSPVPV 577 TP P+ P P EP PT P P TT ++A + LTP+ P Sbjct: 580 TPKEPA-----PTTPKEPA---PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPT-TPE 630 Query: 578 SIQAVNQPLMPLPQT 592 + A P P P T Sbjct: 631 KL-APTTPEKPAPTT 644 Score = 33.9 bits (76), Expect = 0.83 Identities = 35/139 (25%), Positives = 45/139 (32%), Gaps = 17/139 (12%) Query: 461 KRPEPSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTP 520 K P+TL K ++P K E +P K + PAP TP Sbjct: 710 KGTAPTTL------KEPAPTTPKKPAPKEL-APTTTKEPTSTTCDKPAPTTPKGTAPTTP 762 Query: 521 AVPSLPATVPAWPSEPTTFGPTGVPAPIPVL-------SVTQTLTTGPDSAVSQAHLTPS 573 P+ P+ P PT + P P + T T GP S S P+ Sbjct: 763 KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD---KPA 819 Query: 574 PVPVSIQAVNQPLMPLPQT 592 P A P P P T Sbjct: 820 PTTPKETAPTTPKEPAPTT 838 Score = 30.8 bits (68), Expect = 7.0 Identities = 31/135 (22%), Positives = 49/135 (36%), Gaps = 5/135 (3%) Query: 461 KRPEPSTLENI--TDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHL 518 K P P+T + T K ++P K E +P K + PAP Sbjct: 771 KEPAPTTPKGTAPTTLKEPAPTTPKKPAPKEL-APTTTKGPTSTTSDKPAPTTPKETAPT 829 Query: 519 TPAVPSLPATVPAWPSEPTTFGPTGVPAPIPVLS-VTQTLTTGPDSAVSQAHLTPSPVPV 577 TP P+ P+ P T PT P + T+ PD + + P+P + Sbjct: 830 TPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKAL 889 Query: 578 SIQAVNQPLMPLPQT 592 + +P +P +T Sbjct: 890 E-NSPKEPGVPTTKT 903 >gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] Length = 904 Score = 45.8 bits (107), Expect = 2e-04 Identities = 70/317 (22%), Positives = 115/317 (36%), Gaps = 37/317 (11%) Query: 257 KKHTSKNLKAPPPE---SWNTVSGKKMKKPSTSGQNFHSDVDYRGPKNPSKPIK------ 307 ++ T PPP S + V ++ S SG + S R P KP K Sbjct: 324 RRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSS-RSRSPPKKPPKRTSSPP 382 Query: 308 ------APSALPPRLQH-PSGVRQHAFSSHSSGSQSQKFSSEHKNLS----RTPSQIIRK 356 +PSA PPR +H PS + S + Q + +S RT ++ + Sbjct: 383 RKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKH 442 Query: 357 PDRERVEDFDHTSRESNY-FGLSPEERREKQAIEES---RLLYEIQNRDEQAFPALSSSS 412 E+ E + S E++ K A +S R Y QN+ + SSSS Sbjct: 443 KGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSS 502 Query: 413 VNQSASQS--SNPCVQRKSSHVGDRKGSRRRMDTEERKDKDSIHGHSQLDKRPEPSTLEN 470 ++ +S N V R+ H R S +R+ + S G + P P+ Sbjct: 503 EDERPKRSHVKNGEVGRRRRHSPSRSASP---SPRKRQKETSPRGRRRRSPSPPPTRRR- 558 Query: 471 ITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEV--HLTPAVPSLPAT 528 + + + P + ++ P P + P+ +P+P SP + +P+ P T Sbjct: 559 ----RSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRT 614 Query: 529 VPAWPSEPTTFGPTGVP 545 P P+ P Sbjct: 615 ASPPPPPKRRASPSPPP 631 Score = 30.8 bits (68), Expect = 7.0 Identities = 28/141 (19%), Positives = 52/141 (36%), Gaps = 9/141 (6%) Query: 404 AFPALSSSSVNQSASQSSNPCVQRKSSHVGDRKGSRRRMDTEERKDKDSIHGHSQLDKRP 463 AF L + Q + +K D++ + + E++++ S + + P Sbjct: 122 AFLELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRER-SRSPRRRKSRSP 180 Query: 464 EPSTLENIT--DDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPA 521 P + + K + SP K PSPA +K + L P+ + P V + Sbjct: 181 SPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATS 240 Query: 522 VPSL-----PATVPAWPSEPT 537 + P +P P EP+ Sbjct: 241 TSDILKVPKPEPIPE-PKEPS 260 >gi|116284392 mucin 2 precursor [Homo sapiens] Length = 5179 Score = 45.1 bits (105), Expect = 4e-04 Identities = 36/147 (24%), Positives = 48/147 (32%), Gaps = 9/147 (6%) Query: 463 PEPSTLENITDDKYATVSSPSKS------KKLECPSPAEQKPAEHVSLSNPAPLLVSPEV 516 P P T T T S P+ + P P + + P SP Sbjct: 1523 PSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPT 1582 Query: 517 HLTPAVPSLPATVP---AWPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPS 573 TP+ P++ T P PS PTT T P P T +T + TPS Sbjct: 1583 TTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPS 1642 Query: 574 PVPVSIQAVNQPLMPLPQTLSLYQDPL 600 P P + P P T + P+ Sbjct: 1643 PPPTTTTTPPPTTTPSPPTTTTPSPPI 1669 Score = 40.0 bits (92), Expect = 0.012 Identities = 35/141 (24%), Positives = 48/141 (34%), Gaps = 9/141 (6%) Query: 463 PEPSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAV 522 P P T T S P+ + PSP P+ + + P +P T + Sbjct: 1454 PSPPISTTTTPPPTTTPSPPTTT-----PSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPI 1508 Query: 523 --PSLPATVP--AWPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVS 578 P+ T+P PS PTT T P P T +T + TPSP P + Sbjct: 1509 TPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTT 1568 Query: 579 IQAVNQPLMPLPQTLSLYQDP 599 P P T + P Sbjct: 1569 TTTPPPTTTPSPPTTTTPSPP 1589 Score = 39.7 bits (91), Expect = 0.015 Identities = 38/139 (27%), Positives = 49/139 (35%), Gaps = 18/139 (12%) Query: 463 PEPSTLENITDDKYATV------SSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEV 516 P P T IT T SP + P P + S P +P Sbjct: 1618 PSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPP 1677 Query: 517 HLTPAVPSLPATVPAWPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVP 576 TP+ P + PS PTT T P+P S T TT P S TPSP P Sbjct: 1678 TTTPSSP-----ITTTPSPPTTTMTT--PSPTTTPSSPITTTTTPSSTT-----TPSPPP 1725 Query: 577 VSIQAVNQPLMPLPQTLSL 595 ++ + P P T ++ Sbjct: 1726 TTMTTPSPTTTPSPPTTTM 1744 Score = 39.3 bits (90), Expect = 0.020 Identities = 38/129 (29%), Positives = 54/129 (41%), Gaps = 18/129 (13%) Query: 463 PEPSTLEN---ITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSL--SNPAPLLVSPEVH 517 P P+T T T ++PS P P+ ++ S P + +P Sbjct: 1643 PPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPT 1702 Query: 518 LTPAVPSLPATVPA---WPSEP----TTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHL 570 TP+ P T P+ PS P TT PT P+P T T+TT P + S + L Sbjct: 1703 TTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSP-----PTTTMTTLPPTTTS-SPL 1756 Query: 571 TPSPVPVSI 579 T +P+P SI Sbjct: 1757 TTTPLPPSI 1765 Score = 37.0 bits (84), Expect = 0.097 Identities = 38/147 (25%), Positives = 56/147 (38%), Gaps = 16/147 (10%) Query: 463 PEPSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAV 522 P P+ T T ++P P P P S S+P + L PA+ Sbjct: 4186 PTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAI 4245 Query: 523 PSLPATVPAWPSEPTTF--GPTGVPAPIPVLSV----TQTLTTGPDSAVSQAHL------ 570 P+ P+ PTT G T P P S T+ TTG SA + + + Sbjct: 4246 EMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTS 4305 Query: 571 --TPSPVPVSIQAV--NQPLMPLPQTL 593 TP+P P+S ++ L P P ++ Sbjct: 4306 AWTPTPTPLSTPSIIRTTGLRPYPSSV 4332 Score = 36.2 bits (82), Expect = 0.17 Identities = 25/89 (28%), Positives = 34/89 (38%), Gaps = 3/89 (3%) Query: 486 KKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEPTTFGPTGVP 545 K + PSP P+ + + P +P T P T P+ P TT P P Sbjct: 1394 KCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPP---P 1450 Query: 546 APIPVLSVTQTLTTGPDSAVSQAHLTPSP 574 P ++ T T P + S TPSP Sbjct: 1451 TTTPSPPISTTTTPPPTTTPSPPTTTPSP 1479 Score = 36.2 bits (82), Expect = 0.17 Identities = 38/145 (26%), Positives = 52/145 (35%), Gaps = 13/145 (8%) Query: 478 TVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAVPSLPATVPA---WPS 534 T ++P + P+ P + + P S + TP+ P+ T P+ PS Sbjct: 1647 TTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPS 1706 Query: 535 EPTTF----GPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSIQAVNQPLMP-- 588 P T T P+P P T + TT P + P P S PL P Sbjct: 1707 SPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLP-PTTTSSPLTTTPLPPSI 1765 Query: 589 LPQTLSLYQ--DPLYPGFP-CNEKG 610 P T S + P P P CN G Sbjct: 1766 TPPTFSPFSTTTPTTPCVPLCNWTG 1790 Score = 35.4 bits (80), Expect = 0.28 Identities = 33/145 (22%), Positives = 46/145 (31%), Gaps = 8/145 (5%) Query: 463 PEPSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSL----SNPAPLLVSPEVHL 518 P P T T S P+ + P+ P + + P+P + + Sbjct: 1406 PSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPP 1465 Query: 519 TPAVPSLPATVPA----WPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSP 574 PS P T P+ PS PTT T P P T +T + TPSP Sbjct: 1466 PTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSP 1525 Query: 575 VPVSIQAVNQPLMPLPQTLSLYQDP 599 + P P T + P Sbjct: 1526 PTTTTTTPPPTTTPSPPTTTPITPP 1550 Score = 34.7 bits (78), Expect = 0.48 Identities = 22/71 (30%), Positives = 30/71 (42%), Gaps = 2/71 (2%) Query: 523 PSLPATVPA-WPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSIQA 581 PS P T P+ P+ TT PT P+P + T TT P ++ TP P Sbjct: 1399 PSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTT-TTPPPTTTPSPP 1457 Query: 582 VNQPLMPLPQT 592 ++ P P T Sbjct: 1458 ISTTTTPPPTT 1468 Score = 33.9 bits (76), Expect = 0.83 Identities = 26/99 (26%), Positives = 37/99 (37%), Gaps = 10/99 (10%) Query: 489 ECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEPTTFGPTGVP--- 545 E P+P P + P P + T + + P P+ T PT P Sbjct: 1891 ENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITT 1949 Query: 546 ----APIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSIQ 580 P P + TQT TT P + + +TP+P P Q Sbjct: 1950 TTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQ 1986 Score = 33.5 bits (75), Expect = 1.1 Identities = 24/86 (27%), Positives = 33/86 (38%), Gaps = 2/86 (2%) Query: 504 LSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEPTTF-GPTGVPAPIPVLSVTQTLTTGPD 562 ++ P+P +P T P T P+ P+ TT PT P+P + T TT P Sbjct: 1396 ITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPS 1455 Query: 563 SAVSQAHLTPSPVPVSIQAVNQPLMP 588 +S TP P P P Sbjct: 1456 PPISTT-TTPPPTTTPSPPTTTPSPP 1480 Score = 33.1 bits (74), Expect = 1.4 Identities = 31/122 (25%), Positives = 45/122 (36%), Gaps = 8/122 (6%) Query: 463 PEPSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAV 522 P P T T SSP + P+ P+ + S+P +P TP+ Sbjct: 1665 PSPPITTTTTPPPTTTPSSPITTTPSP-PTTTMTTPSPTTTPSSPITTTTTPSSTTTPSP 1723 Query: 523 PSLPATVPA---WPSEPTT----FGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPV 575 P T P+ PS PTT PT +P+ + ++T S S T V Sbjct: 1724 PPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCV 1783 Query: 576 PV 577 P+ Sbjct: 1784 PL 1785 Score = 30.8 bits (68), Expect = 7.0 Identities = 29/125 (23%), Positives = 47/125 (37%), Gaps = 13/125 (10%) Query: 466 STLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAVPSL 525 +T EN T +++ + P+ + ++ + +P TP + Sbjct: 1888 TTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 1947 Query: 526 PATVPAWPSEPTTFG---PTGVP-------APIPVLSVTQTLTTGPDSAVSQAHLTPSPV 575 T P+ PT G PT P P P + TQT TT P + + +TP+P Sbjct: 1948 TTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPT 2004 Query: 576 PVSIQ 580 P Q Sbjct: 2005 PTGTQ 2009 >gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sapiens] Length = 2462 Score = 45.1 bits (105), Expect = 4e-04 Identities = 66/362 (18%), Positives = 129/362 (35%), Gaps = 27/362 (7%) Query: 246 ENGPVLVEELGKKHTSKNLKAPPPESWNTVSGKKMKKPSTSGQNFHSDVDYRGPKNPSKP 305 +NGP LG PPPE + P++ P P P Sbjct: 747 QNGPKPPATLGADGPPPGPPTPPPED---IPAPTEPTPASEATG--------APTPPPAP 795 Query: 306 IKAPSALPPRLQHPSGVRQHAFSSHSSGSQSQKFSSEHKNLSRT-------PSQIIRKPD 358 +PSA PP + + A + + QK + + T S+ + + Sbjct: 796 -PSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELAVDTGKAEEPVKSECTEEAE 854 Query: 359 RERVEDFDHTSRESNYFGLSPEERREKQAIEESRLLYEIQNRDEQAFPALSSSSVNQSAS 418 + D + E+ G E++E + + +D + S+ V+++ Sbjct: 855 EGPAKGKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAEG 914 Query: 419 QSSNPCVQRKSSHV---GDRKGS---RRRMDTEERKDKDSIHGHSQLDKRPEPSTLENIT 472 N + + S + GD + + ++ +D ++ K + + Q+ K EP + Sbjct: 915 GDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRAAAIPPIQVTKVHEPPREDAAP 974 Query: 473 DDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAVPSLPATVPAW 532 P ++ + E +P + + +PAP E P+ A Sbjct: 975 TKPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPP-ADKEAEKPVFFPAFAAEAQKL 1033 Query: 533 PSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSIQAVNQPLMPLPQT 592 P +P + +G+P P+P V + PD + P+P+ + +P++P P T Sbjct: 1034 PGDPPCW-TSGLPFPVPPREVIKASPHAPDPSAFSYAPPGHPLPLGLHDTARPVLPRPPT 1092 Query: 593 LS 594 +S Sbjct: 1093 IS 1094 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 44.3 bits (103), Expect = 6e-04 Identities = 98/406 (24%), Positives = 144/406 (35%), Gaps = 86/406 (21%) Query: 406 PALSSSSVNQSASQSSNPCVQRKSSHVG--DRKGSRRRMDTEERKDKDSIHGHSQLD--- 460 P S SS ++ ++ +P +R+ S G R SR + + G S Sbjct: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPR 264 Query: 461 -----KRPEPSTLENITDDKY-------ATVSSPSKSKKLECPSPAEQKPAEHVSLSNPA 508 +P+P L+ + + A P S L PSP+ K + P Sbjct: 265 APAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTK-------ARPV 317 Query: 509 PLLVSPEVHLTPAVPSLPATVPAWP--SEPTTFGPTGVPAPIPVLSVTQTLTTGPDSAVS 566 P P+ TP LPAT+P P + P P AP + ++ T P A Sbjct: 318 P---PPDNAATP----LPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPP 370 Query: 567 QAHLTPSPVPVSIQAVNQPLMPLPQTLSLYQDPLYPGFPCNEKGDRAIVPPYSLCQTGED 626 P P S+Q + P + +P +L+ PP L + Sbjct: 371 SMTTPPMQAPPSLQTI--PPIQVPHSLT---------------SPSLQAPPSPLALSS-- 411 Query: 627 LPKDKNILRFFFNLGVKAYSCPMWAPHSYLYPLHQAYLAACRMYPKVPVPVYPHNPWFQE 686 L+ +LG S + A HS+L + A P P P +P Q Sbjct: 412 -------LQATTSLG----SPTLQATHSFL-TMSPRQTQASLTSPSRPASTPPDSPPLQ- 458 Query: 687 APAAQNESDCTCTDAHFPMQTEASVNGQMPQPEIGPPTFSSPLVIPPSQVSESHGQLSYQ 746 AP + S P+QT S P + P SSPL I P Q S S Q Sbjct: 459 APLSLPASP--------PLQTSLS-------PAVSP--LSSPLTIHPLQALSSLASHSPQ 501 Query: 747 ADLESETPGQLLHADYEESLSGKNMFPQPSFGPNPFLGPVP-IAPP 791 A L S L + + SL+ ++ P+ P L +P +APP Sbjct: 502 APLSSLIMPPL---ETQSSLAPPSLQTPPASLTTPPLENLPSLAPP 544 Score = 39.7 bits (91), Expect = 0.015 Identities = 76/325 (23%), Positives = 106/325 (32%), Gaps = 40/325 (12%) Query: 477 ATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEP 536 A+ S + L P Q SL P L +P + P++ P + P Sbjct: 496 ASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTT 555 Query: 537 TTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSIQAVNQPLMPLPQTLSLY 596 PAP P+ + LTT P S P P ++ + PL LP Sbjct: 556 PHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPAL--ASPPLQGLP------ 607 Query: 597 QDPLYP-GFPCNEKGDRAIVPPYSLCQTGEDLPKDKNILRFFFNLGVKAYSCPMWAPHSY 655 PL P P + +PP + P L A P AP++ Sbjct: 608 SPPLSPLATPPPQAPPXLALPPLQAPPSPPASPP----------LSPLATPSPQ-APNAL 656 Query: 656 LYPLHQAYLAACRMYPKVPVPVYPHNPWFQE--APAAQNESDCTCTDAHFPMQTEASVNG 713 L QA + P P P +P +P+A S + A P+Q S Sbjct: 657 AVHLLQAPFSP----PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPA 712 Query: 714 Q-------MPQPEIGPPTFSSPLVIPPSQVSESHGQLSYQADLESETPGQLLHADYEESL 766 P P+ PP + PL +PPS + +S A P L + Sbjct: 713 SPPMSPSATPPPQAPPPLAAPPLQVPPSPPASP--PMSPSATPPPRVPPLLAAPPLQVPP 770 Query: 767 SGKNMFPQPSFGPNPFLGPVPIAPP 791 S P S +P P P APP Sbjct: 771 S-----PPASLPMSPLAKPPPQAPP 790 Score = 34.3 bits (77), Expect = 0.63 Identities = 34/113 (30%), Positives = 43/113 (38%), Gaps = 27/113 (23%) Query: 491 PSPAEQKPAEHVSLSNPA--PLLVSPEVHLTPAVP-SLPATVPAWPSEPTTFGPTGVPAP 547 PSP P ++ P P L +P + P+ P S P P PS P P P Sbjct: 770 PSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPP 829 Query: 548 -------IPVLSV------TQTL-------TTGPDSAVSQAHLT----PSPVP 576 P+L V + TL T GPD++VS LT P P P Sbjct: 830 QAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 882 >gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2 [Homo sapiens] Length = 1481 Score = 43.9 bits (102), Expect = 8e-04 Identities = 80/337 (23%), Positives = 128/337 (37%), Gaps = 59/337 (17%) Query: 303 SKPIKAPSALPPRLQHPSGVRQHAFSSHSSG-SQSQKFSSEHKNLSRTPSQIIRKPDRER 361 SK + S LP R S R A+S HSS S+ ++ SS ++ S +P +R P Sbjct: 338 SKRSLSRSPLPSRKSMKSRSRSPAYSRHSSSHSKKKRSSSRSRHSSISP---VRLPLNS- 393 Query: 362 VEDFDHTSRESNYFGLSPEERREKQAIEESRLLYEIQNRDEQAFPALSSSSVNQSASQSS 421 L E R+K+ + ++ ++ + P N S Sbjct: 394 --------------SLGAELSRKKKERAAAAAAAKMDGKESKGSPVFLPRKENSSVEAKD 439 Query: 422 NPCVQRKSSHVGDRKGSR--------RRMDTEERKDKDSIHGHSQLDKRPEPSTLENITD 473 + +K + S ++TE + D+ G +LD+ E ++++ Sbjct: 440 SGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDT--GKVKLDENSEKHLVKDLKA 497 Query: 474 DKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLT-------------- 519 T S + K E +P E + +E + P P + SP L Sbjct: 498 Q--GTRDSKPIALKEEIVTPKETETSEKET-PPPLPTIASPPPPLPTTTPPPQTPPLPPL 554 Query: 520 PAVPSLPATVPAWPSEPTTFGPTGVPAPIPVLSVTQTL---TTGPDSAVSQAHLTPSPVP 576 P +P+LP P PS+P + VPA S T TL T SAVS + PV Sbjct: 555 PPIPALPQQPPLPPSQPAF---SQVPA-----SSTSTLPPSTHSKTSAVSSQANSQPPVQ 606 Query: 577 VSIQAVNQPLMPLP--QTLSLYQDPLYPGFPCNEKGD 611 VS++ +P +T +L PL P P ++ D Sbjct: 607 VSVKTQVSVTAAIPHLKTSTLPPLPLPPLLPGDDDMD 643 Score = 31.6 bits (70), Expect = 4.1 Identities = 37/141 (26%), Positives = 52/141 (36%), Gaps = 16/141 (11%) Query: 232 NGKFLNADVQGIHSENGPVLVEELGKKHTSKNLKAPPPESWNTVSGKK----MKKPSTSG 287 N LN +V+ S+ G V ++E +KH K+LKA ++ K+ K+ TS Sbjct: 464 NVTHLNTEVKN-SSDTGKVKLDENSEKHLVKDLKAQGTRDSKPIALKEEIVTPKETETSE 522 Query: 288 QNFHSDVDYRGPKNPSKPIKAPSALPPRL-----------QHPSGVRQHAFSSHSSGSQS 336 + + P P P P L Q P Q AFS + S S Sbjct: 523 KETPPPLPTIASPPPPLPTTTPPPQTPPLPPLPPIPALPQQPPLPPSQPAFSQVPASSTS 582 Query: 337 QKFSSEHKNLSRTPSQIIRKP 357 S H S SQ +P Sbjct: 583 TLPPSTHSKTSAVSSQANSQP 603 >gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1 [Homo sapiens] Length = 1490 Score = 43.9 bits (102), Expect = 8e-04 Identities = 80/337 (23%), Positives = 128/337 (37%), Gaps = 59/337 (17%) Query: 303 SKPIKAPSALPPRLQHPSGVRQHAFSSHSSG-SQSQKFSSEHKNLSRTPSQIIRKPDRER 361 SK + S LP R S R A+S HSS S+ ++ SS ++ S +P +R P Sbjct: 338 SKRSLSRSPLPSRKSMKSRSRSPAYSRHSSSHSKKKRSSSRSRHSSISP---VRLPLNS- 393 Query: 362 VEDFDHTSRESNYFGLSPEERREKQAIEESRLLYEIQNRDEQAFPALSSSSVNQSASQSS 421 L E R+K+ + ++ ++ + P N S Sbjct: 394 --------------SLGAELSRKKKERAAAAAAAKMDGKESKGSPVFLPRKENSSVEAKD 439 Query: 422 NPCVQRKSSHVGDRKGSR--------RRMDTEERKDKDSIHGHSQLDKRPEPSTLENITD 473 + +K + S ++TE + D+ G +LD+ E ++++ Sbjct: 440 SGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDT--GKVKLDENSEKHLVKDLKA 497 Query: 474 DKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLT-------------- 519 T S + K E +P E + +E + P P + SP L Sbjct: 498 Q--GTRDSKPIALKEEIVTPKETETSEKET-PPPLPTIASPPPPLPTTTPPPQTPPLPPL 554 Query: 520 PAVPSLPATVPAWPSEPTTFGPTGVPAPIPVLSVTQTL---TTGPDSAVSQAHLTPSPVP 576 P +P+LP P PS+P + VPA S T TL T SAVS + PV Sbjct: 555 PPIPALPQQPPLPPSQPAF---SQVPA-----SSTSTLPPSTHSKTSAVSSQANSQPPVQ 606 Query: 577 VSIQAVNQPLMPLP--QTLSLYQDPLYPGFPCNEKGD 611 VS++ +P +T +L PL P P ++ D Sbjct: 607 VSVKTQVSVTAAIPHLKTSTLPPLPLPPLLPGDDDMD 643 Score = 31.6 bits (70), Expect = 4.1 Identities = 37/141 (26%), Positives = 52/141 (36%), Gaps = 16/141 (11%) Query: 232 NGKFLNADVQGIHSENGPVLVEELGKKHTSKNLKAPPPESWNTVSGKK----MKKPSTSG 287 N LN +V+ S+ G V ++E +KH K+LKA ++ K+ K+ TS Sbjct: 464 NVTHLNTEVKN-SSDTGKVKLDENSEKHLVKDLKAQGTRDSKPIALKEEIVTPKETETSE 522 Query: 288 QNFHSDVDYRGPKNPSKPIKAPSALPPRL-----------QHPSGVRQHAFSSHSSGSQS 336 + + P P P P L Q P Q AFS + S S Sbjct: 523 KETPPPLPTIASPPPPLPTTTPPPQTPPLPPLPPIPALPQQPPLPPSQPAFSQVPASSTS 582 Query: 337 QKFSSEHKNLSRTPSQIIRKP 357 S H S SQ +P Sbjct: 583 TLPPSTHSKTSAVSSQANSQP 603 >gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens] Length = 1711 Score = 43.1 bits (100), Expect = 0.001 Identities = 55/207 (26%), Positives = 73/207 (35%), Gaps = 54/207 (26%) Query: 463 PEPSTLENITDDKYATVSSP-SKSKKLECPSPAEQKPAEHVSLSNPAPLLVS-------- 513 P P ++ + D S+P S S + P PA P+ V LS PAP +S Sbjct: 260 PAPPSVPTLISD-----SNPLSVSASVLVPVPASAPPSGPVPLSAPAPAPLSVPVSAPPL 314 Query: 514 -------------------PEVHLTPAVPSLPATVPAWPSEP-----------------T 537 P L P S P PA PS P Sbjct: 315 ALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGPPSTPTLIP 374 Query: 538 TFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSIQAVNQPLMPLPQTLSLYQ 597 F PT VPAP P T T P +A A T +P+P S ++++ P Q ++ + Sbjct: 375 AFAPTPVPAPTPAPIFTPAPTPMP-AATPAAIPTSAPIPASF-SLSRVCFPAAQAPAMQK 432 Query: 598 DPL--YPGFPCNEKGDRAIVPPYSLCQ 622 PL PG +PP S Q Sbjct: 433 VPLSFQPGTVLTPSQPLVYIPPPSCGQ 459 Score = 34.7 bits (78), Expect = 0.48 Identities = 114/509 (22%), Positives = 162/509 (31%), Gaps = 93/509 (18%) Query: 493 PAEQKPAEHVSLSNPAPL----LVSPEVHLTPAVPS-----LPATVPAWPSEPTTF---G 540 P A V LS PAP+ LV +V + PS +PA PA PS PT Sbjct: 214 PHSVPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPSPPLAPVPALAPAPPSVPTLISDSN 273 Query: 541 PTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSIQAVNQPLMPLPQTLSLYQDPL 600 P V A + V +GP + P+P P+S+ P L+L Q P+ Sbjct: 274 PLSVSASVLVPVPASAPPSGPVPLSA-----PAPAPLSVPVSAPP-------LALIQAPV 321 Query: 601 YPGFPCNEKGDRAIVPPYSLCQTGEDLPKDKNILRFFFNLGVKAYSCPMWAPHSYLYPLH 660 P P A VP L P S PM P P Sbjct: 322 PPSAPTLV---LAPVPTPVLAPMPASTPP----------AAPAPPSVPMPTPTPSSGPPS 368 Query: 661 QAYLAACRMYPKVPVPVYPHNPWFQEAPAAQNESDCTCTDAHFPMQTEASVN------GQ 714 L + PVP P F AP + P+ S++ Q Sbjct: 369 TPTLIPA--FAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQ 426 Query: 715 MPQPEIGPPTFSSPLVIPPSQVSESHGQLSYQADLESETPGQLLHADYEESLSGKNMFP- 773 P + P +F V+ PSQ L Y P + +S P Sbjct: 427 APAMQKVPLSFQPGTVLTPSQ------PLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPV 480 Query: 774 QPSFGPNPFLGPVPIAPPFFPHVWYGYPFQGFIENPVMRQNIVLPSDEKGELDLSLENLD 833 PS+ + L V +P YP+ + P L SD K + L + L Sbjct: 481 LPSYLQDRCLPGVLASPEL-----RSYPYAFSVARP-------LTSDSK-LVSLEVNRLP 527 Query: 834 LSKDCGSVSTVDEFPEARGEHVHS----------------LPEASVSSKP------DEGR 871 + GS +T G + LP S SS P G Sbjct: 528 CTSPSGSTTTQPAPDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGT 587 Query: 872 TEQSSQTRKADTALASIPPVAEGKAHPPTQILNRERETVPVELEPKRTIQSLKEKTEKVK 931 +Q+ T + L S P + A PP E +P++L K Q L ++ Sbjct: 588 EQQTEGTSVTFSPLKSPPQLEREMASPP------ECSEMPLDLSSKSNRQKLPLPNQRKT 641 Query: 932 DPKTAADVVSPGANSVDSRVQRPKEESSE 960 P V + ++ S V + +++ Sbjct: 642 PPMPVLTPVHTSSKALLSTVLSRSQRTTQ 670 >gi|189181724 proteoglycan 4 isoform D [Homo sapiens] Length = 1270 Score = 42.4 bits (98), Expect = 0.002 Identities = 47/196 (23%), Positives = 70/196 (35%), Gaps = 10/196 (5%) Query: 404 AFPALSSSSVNQSASQSSNPCVQRKSSHVGDRKGSRRRMD-TEERKDKDSIHGHSQLDKR 462 + P S +S S + + V+ K + +++ S + T K+ SI S D Sbjct: 129 SLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLA 188 Query: 463 PEPSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAV 522 P L T T P+ + E P+P K + P P + TP Sbjct: 189 PTSKVLAKPTPKAETTTKGPALTTPKE-PTPTTPKEPASTTPKEPTPTTIK-SAPTTPKE 246 Query: 523 PSLPATVPAWPSEPTTFGPTGV--PAPIPVLSVTQTLTTGPDSAVSQAHLT----PSPVP 576 P+ P T + P+ P PT PAP T T P +++ T P+P Sbjct: 247 PA-PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT 305 Query: 577 VSIQAVNQPLMPLPQT 592 A P P P T Sbjct: 306 PKKPAPTTPKEPAPTT 321 Score = 36.6 bits (83), Expect = 0.13 Identities = 37/137 (27%), Positives = 47/137 (34%), Gaps = 10/137 (7%) Query: 461 KRPEPSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLV--SPEVHL 518 K P P+T T T P+ + E P+P K + PAP +P Sbjct: 245 KEPAPTT----TKSAPTTPKEPAPTTTKE-PAPTTPKEPAPTTTKEPAPTTTKSAPTTPK 299 Query: 519 TPA--VPSLPA-TVPAWPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPV 575 PA P PA T P P+ T PT P + + T P A P+P Sbjct: 300 EPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPT 359 Query: 576 PVSIQAVNQPLMPLPQT 592 A P P P T Sbjct: 360 TPKEPAPTTPKEPAPTT 376 Score = 35.4 bits (80), Expect = 0.28 Identities = 33/133 (24%), Positives = 41/133 (30%), Gaps = 2/133 (1%) Query: 461 KRPEPSTLENI-TDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLT 519 K P P+T E T K ++P K PA P E + P +P+ Sbjct: 331 KEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP 390 Query: 520 PAVPSLPATVPAWPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSI 579 S P T T PT P P + TT P P+P Sbjct: 391 TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT-PKEPAPTTPKKPAPTTPKE 449 Query: 580 QAVNQPLMPLPQT 592 A P P P T Sbjct: 450 PAPTTPKEPAPTT 462 Score = 35.4 bits (80), Expect = 0.28 Identities = 33/132 (25%), Positives = 45/132 (34%), Gaps = 21/132 (15%) Query: 461 KRPEPSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTP 520 K P P+T + +P+ K+ +P E P L+ P ++P P Sbjct: 456 KEPAPTTTKK---------PAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKP 506 Query: 521 AVPSLPATVPAWPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSIQ 580 A + P P EPT PT P P T P +A P+P Sbjct: 507 APTTPEELAPTTPEEPT---PTTPEEPAP---------TTPKAAAPNTPKEPAPTTPKEP 554 Query: 581 AVNQPLMPLPQT 592 A P P P T Sbjct: 555 APTTPKEPAPTT 566 Score = 34.7 bits (78), Expect = 0.48 Identities = 34/139 (24%), Positives = 47/139 (33%), Gaps = 14/139 (10%) Query: 461 KRPEPSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTP 520 ++P P+T E + T P+ + E P+P K A + PAP TP Sbjct: 504 EKPAPTTPEELAP---TTPEEPTPTTPEE-PAPTTPKAAAPNTPKEPAPTTPKEPAPTTP 559 Query: 521 AVPSLPATVPAWPSEPTTFGPTGVPAPIPVL-------SVTQTLTTGPDSAVSQAHLTPS 573 P+ P+ P PT + P P + T T P S P+ Sbjct: 560 KEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD---KPA 616 Query: 574 PVPVSIQAVNQPLMPLPQT 592 P A P P P T Sbjct: 617 PTTPKGTAPTTPKEPAPTT 635 Score = 34.3 bits (77), Expect = 0.63 Identities = 37/135 (27%), Positives = 51/135 (37%), Gaps = 13/135 (9%) Query: 461 KRPEPSTLENI--TDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHL 518 K P P+T ++ T + A ++ S + PSP K + PAP Sbjct: 386 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 445 Query: 519 TPAVPSLPATVPAWPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSA-VSQAHLTPSPVPV 577 TP P+ P P EP PT P P TT ++A + LTP+ P Sbjct: 446 TPKEPA-----PTTPKEPA---PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPT-TPE 496 Query: 578 SIQAVNQPLMPLPQT 592 + A P P P T Sbjct: 497 KL-APTTPEKPAPTT 510 Score = 33.9 bits (76), Expect = 0.83 Identities = 35/139 (25%), Positives = 45/139 (32%), Gaps = 17/139 (12%) Query: 461 KRPEPSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTP 520 K P+TL K ++P K E +P K + PAP TP Sbjct: 576 KGTAPTTL------KEPAPTTPKKPAPKEL-APTTTKEPTSTTCDKPAPTTPKGTAPTTP 628 Query: 521 AVPSLPATVPAWPSEPTTFGPTGVPAPIPVL-------SVTQTLTTGPDSAVSQAHLTPS 573 P+ P+ P PT + P P + T T GP S S P+ Sbjct: 629 KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD---KPA 685 Query: 574 PVPVSIQAVNQPLMPLPQT 592 P A P P P T Sbjct: 686 PTTPKETAPTTPKEPAPTT 704 Score = 30.8 bits (68), Expect = 7.0 Identities = 31/135 (22%), Positives = 49/135 (36%), Gaps = 5/135 (3%) Query: 461 KRPEPSTLENI--TDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHL 518 K P P+T + T K ++P K E +P K + PAP Sbjct: 637 KEPAPTTPKGTAPTTLKEPAPTTPKKPAPKEL-APTTTKGPTSTTSDKPAPTTPKETAPT 695 Query: 519 TPAVPSLPATVPAWPSEPTTFGPTGVPAPIPVLS-VTQTLTTGPDSAVSQAHLTPSPVPV 577 TP P+ P+ P T PT P + T+ PD + + P+P + Sbjct: 696 TPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKAL 755 Query: 578 SIQAVNQPLMPLPQT 592 + +P +P +T Sbjct: 756 E-NSPKEPGVPTTKT 769 >gi|189181722 proteoglycan 4 isoform C [Homo sapiens] Length = 1311 Score = 42.4 bits (98), Expect = 0.002 Identities = 47/196 (23%), Positives = 70/196 (35%), Gaps = 10/196 (5%) Query: 404 AFPALSSSSVNQSASQSSNPCVQRKSSHVGDRKGSRRRMD-TEERKDKDSIHGHSQLDKR 462 + P S +S S + + V+ K + +++ S + T K+ SI S D Sbjct: 170 SLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLA 229 Query: 463 PEPSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAV 522 P L T T P+ + E P+P K + P P + TP Sbjct: 230 PTSKVLAKPTPKAETTTKGPALTTPKE-PTPTTPKEPASTTPKEPTPTTIK-SAPTTPKE 287 Query: 523 PSLPATVPAWPSEPTTFGPTGV--PAPIPVLSVTQTLTTGPDSAVSQAHLT----PSPVP 576 P+ P T + P+ P PT PAP T T P +++ T P+P Sbjct: 288 PA-PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT 346 Query: 577 VSIQAVNQPLMPLPQT 592 A P P P T Sbjct: 347 PKKPAPTTPKEPAPTT 362 Score = 36.6 bits (83), Expect = 0.13 Identities = 37/137 (27%), Positives = 47/137 (34%), Gaps = 10/137 (7%) Query: 461 KRPEPSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLV--SPEVHL 518 K P P+T T T P+ + E P+P K + PAP +P Sbjct: 286 KEPAPTT----TKSAPTTPKEPAPTTTKE-PAPTTPKEPAPTTTKEPAPTTTKSAPTTPK 340 Query: 519 TPA--VPSLPA-TVPAWPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPV 575 PA P PA T P P+ T PT P + + T P A P+P Sbjct: 341 EPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPT 400 Query: 576 PVSIQAVNQPLMPLPQT 592 A P P P T Sbjct: 401 TPKEPAPTTPKEPAPTT 417 Score = 35.4 bits (80), Expect = 0.28 Identities = 33/133 (24%), Positives = 41/133 (30%), Gaps = 2/133 (1%) Query: 461 KRPEPSTLENI-TDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLT 519 K P P+T E T K ++P K PA P E + P +P+ Sbjct: 372 KEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP 431 Query: 520 PAVPSLPATVPAWPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSI 579 S P T T PT P P + TT P P+P Sbjct: 432 TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT-PKEPAPTTPKKPAPTTPKE 490 Query: 580 QAVNQPLMPLPQT 592 A P P P T Sbjct: 491 PAPTTPKEPAPTT 503 Score = 35.4 bits (80), Expect = 0.28 Identities = 33/132 (25%), Positives = 45/132 (34%), Gaps = 21/132 (15%) Query: 461 KRPEPSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTP 520 K P P+T + +P+ K+ +P E P L+ P ++P P Sbjct: 497 KEPAPTTTKK---------PAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKP 547 Query: 521 AVPSLPATVPAWPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSIQ 580 A + P P EPT PT P P T P +A P+P Sbjct: 548 APTTPEELAPTTPEEPT---PTTPEEPAP---------TTPKAAAPNTPKEPAPTTPKEP 595 Query: 581 AVNQPLMPLPQT 592 A P P P T Sbjct: 596 APTTPKEPAPTT 607 Score = 34.7 bits (78), Expect = 0.48 Identities = 34/139 (24%), Positives = 47/139 (33%), Gaps = 14/139 (10%) Query: 461 KRPEPSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTP 520 ++P P+T E + T P+ + E P+P K A + PAP TP Sbjct: 545 EKPAPTTPEELAP---TTPEEPTPTTPEE-PAPTTPKAAAPNTPKEPAPTTPKEPAPTTP 600 Query: 521 AVPSLPATVPAWPSEPTTFGPTGVPAPIPVL-------SVTQTLTTGPDSAVSQAHLTPS 573 P+ P+ P PT + P P + T T P S P+ Sbjct: 601 KEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD---KPA 657 Query: 574 PVPVSIQAVNQPLMPLPQT 592 P A P P P T Sbjct: 658 PTTPKGTAPTTPKEPAPTT 676 Score = 34.3 bits (77), Expect = 0.63 Identities = 37/135 (27%), Positives = 51/135 (37%), Gaps = 13/135 (9%) Query: 461 KRPEPSTLENI--TDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHL 518 K P P+T ++ T + A ++ S + PSP K + PAP Sbjct: 427 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 486 Query: 519 TPAVPSLPATVPAWPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSA-VSQAHLTPSPVPV 577 TP P+ P P EP PT P P TT ++A + LTP+ P Sbjct: 487 TPKEPA-----PTTPKEPA---PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPT-TPE 537 Query: 578 SIQAVNQPLMPLPQT 592 + A P P P T Sbjct: 538 KL-APTTPEKPAPTT 551 Score = 33.9 bits (76), Expect = 0.83 Identities = 35/139 (25%), Positives = 45/139 (32%), Gaps = 17/139 (12%) Query: 461 KRPEPSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTP 520 K P+TL K ++P K E +P K + PAP TP Sbjct: 617 KGTAPTTL------KEPAPTTPKKPAPKEL-APTTTKEPTSTTCDKPAPTTPKGTAPTTP 669 Query: 521 AVPSLPATVPAWPSEPTTFGPTGVPAPIPVL-------SVTQTLTTGPDSAVSQAHLTPS 573 P+ P+ P PT + P P + T T GP S S P+ Sbjct: 670 KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD---KPA 726 Query: 574 PVPVSIQAVNQPLMPLPQT 592 P A P P P T Sbjct: 727 PTTPKETAPTTPKEPAPTT 745 Score = 30.8 bits (68), Expect = 7.0 Identities = 31/135 (22%), Positives = 49/135 (36%), Gaps = 5/135 (3%) Query: 461 KRPEPSTLENI--TDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHL 518 K P P+T + T K ++P K E +P K + PAP Sbjct: 678 KEPAPTTPKGTAPTTLKEPAPTTPKKPAPKEL-APTTTKGPTSTTSDKPAPTTPKETAPT 736 Query: 519 TPAVPSLPATVPAWPSEPTTFGPTGVPAPIPVLS-VTQTLTTGPDSAVSQAHLTPSPVPV 577 TP P+ P+ P T PT P + T+ PD + + P+P + Sbjct: 737 TPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKAL 796 Query: 578 SIQAVNQPLMPLPQT 592 + +P +P +T Sbjct: 797 E-NSPKEPGVPTTKT 810 >gi|149158690 HLA-B associated transcript-2 [Homo sapiens] Length = 2157 Score = 42.4 bits (98), Expect = 0.002 Identities = 148/663 (22%), Positives = 220/663 (33%), Gaps = 129/663 (19%) Query: 438 SRRRMDTEERKDKDSIHGHSQLDKRPEPSTLENITDDKYATVSSPSKSKKLECPSPAEQK 497 +RRR + EER+ Q ++R + D+K+ +P K K E +P Sbjct: 467 ARRRREEEERR--------MQEERRAACAEKLKRLDEKFG---APDKRLKAEPAAP---- 511 Query: 498 PAEHVSLSNPAPLLVSP-EVHLTPAVPSLPATVPAWPSEPTTFGPTGVPAPIPVLSVTQT 556 PA + S PAP P E+ PA P A P E P P P ++ T Sbjct: 512 PA---APSTPAPPPAVPKELPAPPAPPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPT 568 Query: 557 LTTGPDSAVSQAHLTPSPVPVSIQAVNQPLMPLPQTLSLYQDPLYPGFPCNEKGDRAIVP 616 L +G S S + + PV Q P P+ P P P E I P Sbjct: 569 LVSGGGSTSSTSSGSFEASPVEPQL---PSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGP 625 Query: 617 PYSLCQTGEDLPKDKNILRFFFNLGVKAYSCPMWAPHSYLYPLHQAYLAACRMYPKVPVP 676 G PK + L F + H + HQ A P PVP Sbjct: 626 TRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQ--WQQHQQGSA-----PPTPVP 678 Query: 677 VYPHNP-WFQEAPAAQNESDCTCTDAHFPMQTEASVNGQMPQPEIGPPTFSSP--LVIP- 732 P P PA Q P +A G + +P PP P ++IP Sbjct: 679 PSPPQPVTLGAVPAPQAP----------PPPPKALYPGALGRPPPMPPMNFDPRWMMIPP 728 Query: 733 --------------------------PSQVSESHGQLSYQADLESETPGQLLH-----AD 761 P + S+S G S D P L D Sbjct: 729 YVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFD--RHAPAMLRERGTPPVD 786 Query: 762 YEESLSGKNMFPQPSFGPNPFLGPV---------------PIAPPFFPHV--WYGYPFQG 804 + + G ++F P P P+ P PP P++ + G+P G Sbjct: 787 PKLAWVG-DVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPGFPENG 845 Query: 805 FIENPVMRQNIVLPSDEKGELDLSLENLDLSKDCGSVSTVDEFPEARGEHVHSLPEASVS 864 P+ R P +E G L S + + T E E L Sbjct: 846 APGPPISR----FPLEEPGPRPLPWP--PGSDEVAKIQTPPPKKEPPKEETAQLTGPEAG 899 Query: 865 SKPDEG-----------RTEQSSQTR---KADTALASIPPVAEGKAHPPTQILNRERETV 910 KP G R E ++TR + ++ IPP G PP + ++ Sbjct: 900 RKPARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRGIPPEEPGA--PPRRAGPIKKPPP 957 Query: 911 PVELEPKRTIQSLKEKTEKVKDPKTAADVVSPGANSVDSRVQRPKEESSEDENEVSNILR 970 P ++E + + L++ E K PK ++ G ++ PKE + LR Sbjct: 958 PTKVE-ELPPKPLEQGDETPKPPKPDPLKITKG------KLGGPKETPPNGNLSPAPRLR 1010 Query: 971 SGRSKQFYNQTYGSRKYKSDWGYSGRGGYQHVRSEESWKGQPSRSRDEGYQYHRNVRGRP 1030 S + T + + ++ GRG R +G+ +RSR+ ++ +R RG Sbjct: 1011 RDYSYERVGPTSCRGRGRGEYFARGRG----FRGTYGGRGRGARSRE--FRSYREFRGDD 1064 Query: 1031 FRG 1033 RG Sbjct: 1065 GRG 1067 Score = 31.2 bits (69), Expect = 5.3 Identities = 25/69 (36%), Positives = 35/69 (50%), Gaps = 4/69 (5%) Query: 269 PESWNTVSGKKMKKPSTSGQNFHSDVDYRGPKNPSKPIKAPSALPPRLQHPS--GVRQHA 326 P+S N SG + +PS+SGQ + +V Y G PS + A+ +L HP+ G R Sbjct: 1811 PQSKNLDSGHCVPEPSSSGQRLYPEVFY-GSAGPSSSQISGGAMDSQL-HPNSGGFRPGT 1868 Query: 327 FSSHSSGSQ 335 S H SQ Sbjct: 1869 PSLHPYRSQ 1877 >gi|55953110 retinoblastoma protein-binding zinc finger protein isoform c [Homo sapiens] Length = 1481 Score = 42.4 bits (98), Expect = 0.002 Identities = 59/224 (26%), Positives = 82/224 (36%), Gaps = 39/224 (17%) Query: 410 SSSVNQSASQSSNPCVQRKS--------SHVGDRKGSRRRMDTEERKDKDSIHGHSQLDK 461 SS V Q A + VQ +S H D +G +E K+ S+ K Sbjct: 626 SSGVKQKAEGTGKTPVQWESVLDLSVHKKHCSDSEG-------KEFKESHSVQPTCSAVK 678 Query: 462 RPEPST--LENITDDKYATVSSPSKSKK--LECPSPAEQKPAEHVSLSNPAPLLVSPEVH 517 + +P+T L+ + ++Y + P ++ PSP + A+ P +P V Sbjct: 679 KRKPTTCMLQKVLLNEYNGIDLPVENPADGTRSPSPCKSLEAQPDPDLGPGSGFPAPTVE 738 Query: 518 LTPAV---------PSL------PATVPAWPSEPTTFGPT-GVPAPIPVLSVTQTLTTGP 561 TP V PSL P +P PS P P V P P L T L Sbjct: 739 STPDVCPSSPALQTPSLSSGQLPPLLIPTDPSSPPPCPPVLTVATPPPPLLPTVPLPAPS 798 Query: 562 DSAVSQAHLTPSPVPVSIQAVNQPLMPLPQTLSLYQDPLYPGFP 605 SA P P P+S PL L T+S P+ P P Sbjct: 799 SSASPH----PCPSPLSNATAQSPLPILSPTVSPSPSPIPPVEP 838 >gi|20336260 retinoblastoma protein-binding zinc finger protein isoform b [Homo sapiens] Length = 1682 Score = 42.4 bits (98), Expect = 0.002 Identities = 59/224 (26%), Positives = 82/224 (36%), Gaps = 39/224 (17%) Query: 410 SSSVNQSASQSSNPCVQRKS--------SHVGDRKGSRRRMDTEERKDKDSIHGHSQLDK 461 SS V Q A + VQ +S H D +G +E K+ S+ K Sbjct: 827 SSGVKQKAEGTGKTPVQWESVLDLSVHKKHCSDSEG-------KEFKESHSVQPTCSAVK 879 Query: 462 RPEPST--LENITDDKYATVSSPSKSKK--LECPSPAEQKPAEHVSLSNPAPLLVSPEVH 517 + +P+T L+ + ++Y + P ++ PSP + A+ P +P V Sbjct: 880 KRKPTTCMLQKVLLNEYNGIDLPVENPADGTRSPSPCKSLEAQPDPDLGPGSGFPAPTVE 939 Query: 518 LTPAV---------PSL------PATVPAWPSEPTTFGPT-GVPAPIPVLSVTQTLTTGP 561 TP V PSL P +P PS P P V P P L T L Sbjct: 940 STPDVCPSSPALQTPSLSSGQLPPLLIPTDPSSPPPCPPVLTVATPPPPLLPTVPLPAPS 999 Query: 562 DSAVSQAHLTPSPVPVSIQAVNQPLMPLPQTLSLYQDPLYPGFP 605 SA P P P+S PL L T+S P+ P P Sbjct: 1000 SSASPH----PCPSPLSNATAQSPLPILSPTVSPSPSPIPPVEP 1039 >gi|20336258 retinoblastoma protein-binding zinc finger protein isoform a [Homo sapiens] Length = 1718 Score = 42.4 bits (98), Expect = 0.002 Identities = 59/224 (26%), Positives = 82/224 (36%), Gaps = 39/224 (17%) Query: 410 SSSVNQSASQSSNPCVQRKS--------SHVGDRKGSRRRMDTEERKDKDSIHGHSQLDK 461 SS V Q A + VQ +S H D +G +E K+ S+ K Sbjct: 827 SSGVKQKAEGTGKTPVQWESVLDLSVHKKHCSDSEG-------KEFKESHSVQPTCSAVK 879 Query: 462 RPEPST--LENITDDKYATVSSPSKSKK--LECPSPAEQKPAEHVSLSNPAPLLVSPEVH 517 + +P+T L+ + ++Y + P ++ PSP + A+ P +P V Sbjct: 880 KRKPTTCMLQKVLLNEYNGIDLPVENPADGTRSPSPCKSLEAQPDPDLGPGSGFPAPTVE 939 Query: 518 LTPAV---------PSL------PATVPAWPSEPTTFGPT-GVPAPIPVLSVTQTLTTGP 561 TP V PSL P +P PS P P V P P L T L Sbjct: 940 STPDVCPSSPALQTPSLSSGQLPPLLIPTDPSSPPPCPPVLTVATPPPPLLPTVPLPAPS 999 Query: 562 DSAVSQAHLTPSPVPVSIQAVNQPLMPLPQTLSLYQDPLYPGFP 605 SA P P P+S PL L T+S P+ P P Sbjct: 1000 SSASPH----PCPSPLSNATAQSPLPILSPTVSPSPSPIPPVEP 1039 >gi|47132519 Ras association and pleckstrin homology domains 1 isoform 1 [Homo sapiens] Length = 1250 Score = 42.4 bits (98), Expect = 0.002 Identities = 63/253 (24%), Positives = 85/253 (33%), Gaps = 43/253 (16%) Query: 482 PSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEPTTFGP 541 P+ + PA P+ + P PL + H+T P P P P P P Sbjct: 719 PTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTP---PPPPPIPAPLPP 775 Query: 542 TGVPAP-IPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSIQAVNQPLMPLPQTLSLYQDPL 600 P P + + + T T T P V+QA P+P P A QP P + Y P Sbjct: 776 QAPPKPLVTIPAPTSTKTVAP--VVTQA-APPTPTPPVPPAKKQPAFP-----ASYIPPS 827 Query: 601 YPGFPCNEKGDRAIVPPYSLCQTGEDLPKDKNILRFFFNLGVKAYSCPMWAPHSYLYPLH 660 P P VPP LPK ++ C P S L P+ Sbjct: 828 PPTPP-------VPVPP-------PTLPKQQSF-------------CAK-PPPSPLSPVP 859 Query: 661 QAYLAACRMYPKVPVPVYPHNPWFQEAPAAQNESDCTCTDAHFPMQTEASVNGQMPQPEI 720 +P P P + + PA A P +S+ +P P+ Sbjct: 860 SVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAK-PKWQPSSI--PVPSPDF 916 Query: 721 GPPTFSSPLVIPP 733 PP S LV PP Sbjct: 917 PPPPPESSLVFPP 929 Score = 37.4 bits (85), Expect = 0.075 Identities = 50/195 (25%), Positives = 73/195 (37%), Gaps = 7/195 (3%) Query: 396 EIQNRDEQAFP--ALSSSSVNQSASQSSNPCVQRKSSHVGDRKGSRRRMDTEERKDKDSI 453 E R E A+ +LSSSS+ +S SS P Q S+ D S + R Sbjct: 515 EALKRTESAYDWTSLSSSSIKSGSSSSSIPESQSNHSNQSDSGVSDTQPAGHVRSQSIVS 574 Query: 454 HGHSQLDKRPEPSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVS 513 S+ KR + LE + + +++ P S L P + K + S P+P L Sbjct: 575 SVFSEAWKRG--TQLEESSKARMESMNRPYTS--LVPPLSPQPKIVTPYTASQPSPPLPP 630 Query: 514 PEVHLTPAVPSLPATVPAWPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPS 573 P P P P P PS+ + P + ++T+ S TP Sbjct: 631 PPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTP- 689 Query: 574 PVPVSIQAVNQPLMP 588 PV S Q L+P Sbjct: 690 PVMQSQSVKPQILVP 704 Score = 37.0 bits (84), Expect = 0.097 Identities = 41/167 (24%), Positives = 62/167 (37%), Gaps = 22/167 (13%) Query: 458 QLDKRPEPSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNP------APLL 511 Q P P + + +P + P P + P V++ P AP + Sbjct: 739 QFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAP-V 797 Query: 512 VSPEVHLTPAVPSLPA-TVPAWPSE--PTTFGPTGVPAPIPVLSVTQTLTTGP------- 561 V+ TP P PA PA+P+ P + VP P P L Q+ P Sbjct: 798 VTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSP 857 Query: 562 -DSAVSQ--AHLTPSPVPVSIQAVNQPLMPLPQTLSLYQDPLYPGFP 605 S V Q + P P P +++ +QPL P+P ++ P P Sbjct: 858 VPSVVKQIASQFPPPPTPPAME--SQPLKPVPANVAPQSPPAVKAKP 902 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.311 0.129 0.382 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 47,521,521 Number of Sequences: 37866 Number of extensions: 2635350 Number of successful extensions: 11685 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 41 Number of HSP's successfully gapped in prelim test: 533 Number of HSP's that attempted gapping in prelim test: 9672 Number of HSP's gapped (non-prelim): 2317 length of query: 1049 length of database: 18,247,518 effective HSP length: 113 effective length of query: 936 effective length of database: 13,968,660 effective search space: 13074665760 effective search space used: 13074665760 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.