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Search of human proteins with 110556644
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|110556644 zinc finger protein, multitype 1 [Homo sapiens]
(1006 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|110556644 zinc finger protein, multitype 1 [Homo sapiens] 2106 0.0
gi|223890230 zinc finger protein, multitype 2 [Homo sapiens] 379 e-105
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 109 1e-23
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 106 1e-22
gi|163965366 nascent polypeptide-associated complex alpha subuni... 105 2e-22
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 100 7e-21
gi|148276998 zinc finger protein 628 [Homo sapiens] 100 7e-21
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 97 8e-20
gi|110832843 TBP-associated factor 4 [Homo sapiens] 92 2e-18
gi|160707881 formin 2 [Homo sapiens] 90 9e-18
gi|150170670 piccolo isoform 2 [Homo sapiens] 88 5e-17
gi|150378539 piccolo isoform 1 [Homo sapiens] 88 5e-17
gi|210031154 zinc finger protein 541 [Homo sapiens] 86 2e-16
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 85 4e-16
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 85 4e-16
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens] 82 2e-15
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens] 82 2e-15
gi|47132519 Ras association and pleckstrin homology domains 1 is... 82 3e-15
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 82 3e-15
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s... 82 3e-15
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa... 82 3e-15
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s... 82 3e-15
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 80 7e-15
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 79 2e-14
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 78 4e-14
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 78 4e-14
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens] 77 6e-14
gi|153792074 proline rich 12 [Homo sapiens] 77 8e-14
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [... 76 2e-13
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 75 2e-13
>gi|110556644 zinc finger protein, multitype 1 [Homo sapiens]
Length = 1006
Score = 2106 bits (5456), Expect = 0.0
Identities = 1006/1006 (100%), Positives = 1006/1006 (100%)
Query: 1 MSRRKQSNPRQIKRSLGDMEAREEVQLVGASHMEQKATAPEAPSPPSADVNSPPPLPPPT 60
MSRRKQSNPRQIKRSLGDMEAREEVQLVGASHMEQKATAPEAPSPPSADVNSPPPLPPPT
Sbjct: 1 MSRRKQSNPRQIKRSLGDMEAREEVQLVGASHMEQKATAPEAPSPPSADVNSPPPLPPPT 60
Query: 61 SPGGPKELEGQEPEPRPTEEEPGSPWSGPDELEPVVQDGQRRIRARLSLATGLSWGPFHG 120
SPGGPKELEGQEPEPRPTEEEPGSPWSGPDELEPVVQDGQRRIRARLSLATGLSWGPFHG
Sbjct: 61 SPGGPKELEGQEPEPRPTEEEPGSPWSGPDELEPVVQDGQRRIRARLSLATGLSWGPFHG 120
Query: 121 SVQTRASSPRQAEPSPALTLLLVDEACWLRTLPQALTEAEANTEIHRKDDALWCRVTKPV 180
SVQTRASSPRQAEPSPALTLLLVDEACWLRTLPQALTEAEANTEIHRKDDALWCRVTKPV
Sbjct: 121 SVQTRASSPRQAEPSPALTLLLVDEACWLRTLPQALTEAEANTEIHRKDDALWCRVTKPV 180
Query: 181 PAGGLLSVLLTAEPHSTPGHPVKKEPAEPTCPAPAHDLQLLPQQAGMASILATAVINKDV 240
PAGGLLSVLLTAEPHSTPGHPVKKEPAEPTCPAPAHDLQLLPQQAGMASILATAVINKDV
Sbjct: 181 PAGGLLSVLLTAEPHSTPGHPVKKEPAEPTCPAPAHDLQLLPQQAGMASILATAVINKDV 240
Query: 241 FPCKDCGIWYRSERNLQAHLLYYCASRQGTGSPAAAATDEKPKETYPNERVCPFPQCRKS 300
FPCKDCGIWYRSERNLQAHLLYYCASRQGTGSPAAAATDEKPKETYPNERVCPFPQCRKS
Sbjct: 241 FPCKDCGIWYRSERNLQAHLLYYCASRQGTGSPAAAATDEKPKETYPNERVCPFPQCRKS 300
Query: 301 CPSASSLEIHMRSHSGERPFVCLICLSAFTTKANCERHLKVHTDTLSGVCHSCGFISTTR 360
CPSASSLEIHMRSHSGERPFVCLICLSAFTTKANCERHLKVHTDTLSGVCHSCGFISTTR
Sbjct: 301 CPSASSLEIHMRSHSGERPFVCLICLSAFTTKANCERHLKVHTDTLSGVCHSCGFISTTR 360
Query: 361 DILYSHLVTNHMVCQPGSKGEIYSPGAGHPATKLPPDSLGSFQQQHTALQGPLASADLGL 420
DILYSHLVTNHMVCQPGSKGEIYSPGAGHPATKLPPDSLGSFQQQHTALQGPLASADLGL
Sbjct: 361 DILYSHLVTNHMVCQPGSKGEIYSPGAGHPATKLPPDSLGSFQQQHTALQGPLASADLGL 420
Query: 421 APTPSPGLDRKALAEATNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILGPGE 480
APTPSPGLDRKALAEATNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILGPGE
Sbjct: 421 APTPSPGLDRKALAEATNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILGPGE 480
Query: 481 PGPQAPSRTPSPRSPAPARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGPDAAPPAS 540
PGPQAPSRTPSPRSPAPARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGPDAAPPAS
Sbjct: 481 PGPQAPSRTPSPRSPAPARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGPDAAPPAS 540
Query: 541 EILAKMSELVHSRLQQGAGAGAGGAQTGLFPGAPKGATCFECEITFSNVNNYYVHKRLYC 600
EILAKMSELVHSRLQQGAGAGAGGAQTGLFPGAPKGATCFECEITFSNVNNYYVHKRLYC
Sbjct: 541 EILAKMSELVHSRLQQGAGAGAGGAQTGLFPGAPKGATCFECEITFSNVNNYYVHKRLYC 600
Query: 601 SGRRAPEDAPAARRPKAPPGPARAPPGQPAEPDAPRSSPGPGAREEGAGGAATPEDGAGG 660
SGRRAPEDAPAARRPKAPPGPARAPPGQPAEPDAPRSSPGPGAREEGAGGAATPEDGAGG
Sbjct: 601 SGRRAPEDAPAARRPKAPPGPARAPPGQPAEPDAPRSSPGPGAREEGAGGAATPEDGAGG 660
Query: 661 RGSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRPAAP 720
RGSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRPAAP
Sbjct: 661 RGSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRPAAP 720
Query: 721 PGPPGPAAPPAPSPAAPVRTRRRRKLYELHAAGAPPPPPPGHAPAPESPRPGSGSGSGPG 780
PGPPGPAAPPAPSPAAPVRTRRRRKLYELHAAGAPPPPPPGHAPAPESPRPGSGSGSGPG
Sbjct: 721 PGPPGPAAPPAPSPAAPVRTRRRRKLYELHAAGAPPPPPPGHAPAPESPRPGSGSGSGPG 780
Query: 781 LAPARSPGPAADGPIDLSKKPRRPLPGAPAPALADYHECTACRVSFHSLEAYLAHKKYSC 840
LAPARSPGPAADGPIDLSKKPRRPLPGAPAPALADYHECTACRVSFHSLEAYLAHKKYSC
Sbjct: 781 LAPARSPGPAADGPIDLSKKPRRPLPGAPAPALADYHECTACRVSFHSLEAYLAHKKYSC 840
Query: 841 PAAPPPGALGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGPGVEARTPADRGP 900
PAAPPPGALGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGPGVEARTPADRGP
Sbjct: 841 PAAPPPGALGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGPGVEARTPADRGP 900
Query: 901 SPAPAPAASPQPGSRGPRDGLGPEPQEPPPGPPPSPAAAPEAVPPPPAPPSYSDKGVQTP 960
SPAPAPAASPQPGSRGPRDGLGPEPQEPPPGPPPSPAAAPEAVPPPPAPPSYSDKGVQTP
Sbjct: 901 SPAPAPAASPQPGSRGPRDGLGPEPQEPPPGPPPSPAAAPEAVPPPPAPPSYSDKGVQTP 960
Query: 961 SKGTPAPLPNGNHRYCRLCNIKFSSLSTFIAHKKYYCSSHAAEHVK 1006
SKGTPAPLPNGNHRYCRLCNIKFSSLSTFIAHKKYYCSSHAAEHVK
Sbjct: 961 SKGTPAPLPNGNHRYCRLCNIKFSSLSTFIAHKKYYCSSHAAEHVK 1006
>gi|223890230 zinc finger protein, multitype 2 [Homo sapiens]
Length = 1151
Score = 379 bits (974), Expect = e-105
Identities = 311/959 (32%), Positives = 431/959 (44%), Gaps = 199/959 (20%)
Query: 1 MSRRKQSNPRQIKRSLGDMEAREEVQLVGASHMEQKATAPEAPSPPSADVNSPPPLPPPT 60
MSRRKQS PRQIKR L D EE E PS + D+ S P
Sbjct: 1 MSRRKQSKPRQIKRPLEDAIEDEE---------------EECPSEET-DIISKGDFPLEE 44
Query: 61 SPG---GPKEL------------------EGQEPEPRPTEEEPGSP------WSGPDELE 93
S GP+ L E E + E+PG P W GP ELE
Sbjct: 45 SFSTEFGPENLSCEEVEYFCNKGDDEGIQETAESDGDTQSEKPGQPGVETDDWDGPGELE 104
Query: 94 PVVQDGQRRIRARLSLATGLSWGPFHGSVQTRASSPRQAEPSPALTLLLVDEACWLRTLP 153
+DG+R+I++R L G +WGPF G + +S + P ++L WL +
Sbjct: 105 VFQKDGERKIQSRQQLPVGTTWGPFPGKMDLNNNSLKTKAQVP---MVLTAGPKWLLDVT 161
Query: 154 -QALTEAEANTEIHRKDDALWCRVTKPVPAGGLLSVLLTAEPHSTPGHPVKKEPAEPTCP 212
Q + + + N ++ K LWC TK + G L + + S + E P
Sbjct: 162 WQGVEDNKNNCIVYSKGGQLWCTTTKAISEGEEL-IAFVVDFDSRLQAASQMTLTEGMYP 220
Query: 213 APAHD-LQLLPQQAGMASILATAVINKDVFPCKDCGIWYRSERNLQAHLLYYCASRQGTG 271
A D +QLLPQQA MASIL TA++NKD+FPCK CGIWYRSERNLQAHL+YYC+ RQ
Sbjct: 221 ARLLDSIQLLPQQAAMASILPTAIVNKDIFPCKSCGIWYRSERNLQAHLMYYCSGRQREA 280
Query: 272 SPAAAATDEKPKETYPNERVCPFPQCRKSCPSASSLEIHMRSHSGER---------PFVC 322
+P + +E + +CPFPQC KS +A +LE+H+ SHSG + C
Sbjct: 281 APVS---EENEDSAHQISSLCPFPQCTKSFSNARALEMHLNSHSGVKMEEFLPPGASLKC 337
Query: 323 LICLSAFTTKANCERHLKVHTDTLSGVCHSCGFISTTRDILYSHLVTNHMVCQPGSKGEI 382
+C + N +HL H + C+ C F T+ L H E+
Sbjct: 338 TVCSYTADSVINFHQHLFSHLTQAAFRCNHCHFGFQTQRELLQHQ-------------EL 384
Query: 383 YSPGAGHPATKLPPDSLGSFQQQHTALQGPLASADLGLAPTPSPGLDRKALAEATNGEAR 442
+ P KLP +S +H SP +L AT+ R
Sbjct: 385 HVPSG-----KLPRES----DMEH------------------SPSATEDSLQPATDLLTR 417
Query: 443 AEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILGPGEPGPQAPSRTPSPRSPAPARVKA 502
+E L Q+ + + A +++ E+ + L P Q T + +S + ++K+
Sbjct: 418 SE-LPQSQKAMQTKDASSDTELDKCEK-KTQLFLTNQRPEIQP---TTNKQSFSYTKIKS 472
Query: 503 ELSSPTPGSSPVPGELGLAGAL--FLPQYVFGPDAA--PPASEILAKMSELVHSRLQQGA 558
E SSP SSPV +G + + FL Q+ F D P ASEILAKMSELVH RL+ G+
Sbjct: 473 EPSSPRLASSPVQPNIGPSFPVGPFLSQFSFPQDITMVPQASEILAKMSELVHRRLRHGS 532
Query: 559 GAGAGGAQTGLFPGAPKGATCFECEITFSNVNNYYVHKRLYCSGR-----RAPE-DAPAA 612
+ + L P KGATCFEC ITF+N++NY VHK+ YCS R ++PE + +
Sbjct: 533 SSYPPVIYSPLMP---KGATCFECNITFNNLDNYLVHKKHYCSSRWQQMAKSPEFPSVSE 589
Query: 613 RRPKA-PPGPARA------PPGQPAEPDAP-------RSSP-----GPGAR--------- 644
+ P+A P + P A+P+ P SS GP +
Sbjct: 590 KMPEALSPNTGQTSINLLNPAAHSADPENPLLQTSCINSSTVLDLIGPNGKGHDKDFSTQ 649
Query: 645 EEGAGGAATPEDGAGGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRY 704
+ ++ +D G+ + ++P + D E DP++T CEACNI FSRHETY VHK+Y
Sbjct: 650 TKKLSTSSNNDDKINGKPVD-VKNPSVPLVDGESDPNKTTCEACNITFSRHETYMVHKQY 708
Query: 705 YCASRHDPPPRRPAAPPGPPGPAAPPAPSPAAPVRTRRRRKLYELHAAGAPPPPP----- 759
YCA+RHDPP +R A+ P+ +RTR+RRK+YE+ PP
Sbjct: 709 YCATRHDPPLKR---------SASNKVPAMQRTMRTRKRRKMYEMCLPEQEQRPPLVQQR 759
Query: 760 -----PGHAPAPESPRPGSGSGS--------GPGLAPARSPGPAA--------------- 791
+ P + P G G PG+
Sbjct: 760 FLDVANLNNPCTSTQEPTEGLGECYHPRCDIFPGIVSKHLETSLTINKCVPVSKCDTTHS 819
Query: 792 -------DGPIDLSKK--PRRPLPGAPAPALADYHECTACRVSFHSLEAYLAHKKYSCP 841
D PIDLSKK + L DYHECT C++SF+ +E YLAHK+ CP
Sbjct: 820 SVSCLEMDVPIDLSKKCLSQSERTTTSPKRLLDYHECTVCKISFNKVENYLAHKQNFCP 878
Score = 71.6 bits (174), Expect = 3e-12
Identities = 49/110 (44%), Positives = 60/110 (54%), Gaps = 21/110 (19%)
Query: 906 PAASPQPGSRGPRDGLGPEPQEPPPGPPPS-----PAAAPEAVPP--PPAPPSYSD--KG 956
PAA+PQ ++ + PQ PS P AA E V P P A S KG
Sbjct: 1054 PAANPQ------QENISQNPQHEDDHKSPSWISENPLAANENVSPGIPSAEEQLSSIAKG 1107
Query: 957 VQTPSKGTPAPLPNGNHRYCRLCNIKFSSLSTFIAHKKYYCSSHAAEHVK 1006
V S+ AP +YCRLC+I+F++LS FI HKK+YCSSHAAEHVK
Sbjct: 1108 VNGSSQ---APTSG---KYCRLCDIQFNNLSNFITHKKFYCSSHAAEHVK 1151
Score = 55.5 bits (132), Expect = 3e-07
Identities = 74/347 (21%), Positives = 115/347 (33%), Gaps = 43/347 (12%)
Query: 680 PSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRPAAPPGPPGPAAPPAPSPAAPVR 739
P C CNI F+ + Y VHK++YC+SR + P P + P +P
Sbjct: 545 PKGATCFECNITFNNLDNYLVHKKHYCSSRWQQMAKSPEFPS-----VSEKMPEALSPNT 599
Query: 740 TRRRRKLYELHAAGAPPPPPPGHAPAPESPRP-------GSG-----SGSGPGLAPARSP 787
+ L A A P P S G G S L+ + +
Sbjct: 600 GQTSINLLNPAAHSADPENPLLQTSCINSSTVLDLIGPNGKGHDKDFSTQTKKLSTSSNN 659
Query: 788 GPAADG-PIDLSKKPRRPLPGAPAPALADYHECTACRVSFHSLEAYLAHKKYSCPAAPPP 846
+G P+D+ K P PL + + C AC ++F E Y+ HK+Y C P
Sbjct: 660 DDKINGKPVDV-KNPSVPLVDGESDP--NKTTCEACNITFSRHETYMVHKQYYCATRHDP 716
Query: 847 GALGLPAAACP----------------YCPPNGPVRGDLLEHFRLAHGLLLGAPLAGPGV 890
+ P C P R L++ L A L P
Sbjct: 717 PLKRSASNKVPAMQRTMRTRKRRKMYEMCLPEQEQRPPLVQ-----QRFLDVANLNNPCT 771
Query: 891 EARTPADRGPSPAPAPAASPQPGSRGPRDGLGPEPQEPPPGPPPSPAAAPEAVPPPPAPP 950
+ P + G P PG + P + + P
Sbjct: 772 STQEPTE-GLGECYHPRCDIFPGIVSKHLETSLTINKCVPVSKCDTTHSSVSCLEMDVPI 830
Query: 951 SYSDKGVQTPSKGTPAPLPNGNHRYCRLCNIKFSSLSTFIAHKKYYC 997
S K + + T +P ++ C +C I F+ + ++AHK+ +C
Sbjct: 831 DLSKKCLSQSERTTTSPKRLLDYHECTVCKISFNKVENYLAHKQNFC 877
Score = 37.7 bits (86), Expect = 0.055
Identities = 17/42 (40%), Positives = 23/42 (54%), Gaps = 4/42 (9%)
Query: 962 KGTPAPLPNG----NHRYCRLCNIKFSSLSTFIAHKKYYCSS 999
K PL +G N C CNI FS T++ HK+YYC++
Sbjct: 671 KNPSVPLVDGESDPNKTTCEACNITFSRHETYMVHKQYYCAT 712
Score = 36.6 bits (83), Expect = 0.12
Identities = 14/31 (45%), Positives = 20/31 (64%)
Query: 976 CRLCNIKFSSLSTFIAHKKYYCSSHAAEHVK 1006
C CNI F++L ++ HKK+YCSS + K
Sbjct: 550 CFECNITFNNLDNYLVHKKHYCSSRWQQMAK 580
Score = 35.8 bits (81), Expect = 0.21
Identities = 13/30 (43%), Positives = 19/30 (63%)
Query: 576 GATCFECEITFSNVNNYYVHKRLYCSGRRA 605
G C C+I F+N++N+ HK+ YCS A
Sbjct: 1118 GKYCRLCDIQFNNLSNFITHKKFYCSSHAA 1147
Score = 32.0 bits (71), Expect = 3.0
Identities = 20/71 (28%), Positives = 31/71 (43%), Gaps = 17/71 (23%)
Query: 638 SPGPGAREEGAGGAATPEDGAGGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHET 697
SPG + EE A +G+ SQ+P S C C+I+F+
Sbjct: 1091 SPGIPSAEEQLSSIAKGVNGS-------SQAPTSG----------KYCRLCDIQFNNLSN 1133
Query: 698 YTVHKRYYCAS 708
+ HK++YC+S
Sbjct: 1134 FITHKKFYCSS 1144
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 109 bits (272), Expect = 1e-23
Identities = 162/632 (25%), Positives = 222/632 (35%), Gaps = 106/632 (16%)
Query: 390 PATKLPPDSLGSFQQQHTALQGPLA----SADLGLAPTPSPGLDRKAL---AEATNG-EA 441
P T+ P S+ S + T P A SA GL S L A + A +G A
Sbjct: 200 PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSA 259
Query: 442 RAEPLAQNGGSSEPPAAPRSIKVEAVEEP--EAAPILGPGEPGPQA---PSRTPSPRSPA 496
R P A S P ++++ V P +AAP LGP P A PS T + P
Sbjct: 260 RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPP 319
Query: 497 PARVKAELSSPTPGSSPVPGELGLAG--------------------ALFLPQYVFGPDAA 536
P L + P S P+ L LA + P P A
Sbjct: 320 PDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQA 379
Query: 537 PPASEILAKMSELVHSRLQQGAGAGAGGAQTGLFPGAPKGATCFECEITFSNVNNYYVHK 596
PP+ + + + ++ HS A P +P + + + + H
Sbjct: 380 PPSLQTIPPI-QVPHSLTSPSLQA----------PPSPLALSSLQATTSLGSPTLQATHS 428
Query: 597 RLYCSGRRAPEDAPAARRPKAPPG---PARAPPGQPAEPDAPRSSPGPGAREEGAGGAAT 653
L S R+ + RP + P P +AP PA P ++S P +
Sbjct: 429 FLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPL-QTSLSPAVSPLSSPLTIH 487
Query: 654 PEDGAGGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPP 713
P S Q+P SS+ + +L + + T S PP
Sbjct: 488 PLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPS--LQTPPASLTTPPLENLPSLAPPP 545
Query: 714 PRRPAAP------PGPPGPAAPPAPSPAAPVRTRRRRKLYELHAAGAPPP--------PP 759
+ +AP PP PA P +P +P+ T PPP PP
Sbjct: 546 LQTASAPLTTPHLETPPCPAPCPLQAPPSPLTT--------------PPPETPSSIATPP 591
Query: 760 PGHAPAPESPRPGSGSGSGPGLAPARSPGPAADGPIDLSKKPRRPLPGAPAPA--LADYH 817
P PA SP P G S P L+P +P P A + L P P A P LA
Sbjct: 592 PQAPPALASP-PLQGLPSPP-LSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPS 649
Query: 818 ECTACRVSFHSLEAYLAHKKYSCPAAPPPGALGLPAAACPYCPPNGPVRGDLLEHFRLAH 877
++ H L+A P +PPP P P+ PP P A
Sbjct: 650 PQAPNALAVHLLQA---------PFSPPPS----PPVQAPFSPPASPPVSPSATPPSQAP 696
Query: 878 GLLLGAPLAGPGVEARTPADRGPSPAPAPAASPQPGSRGPRDGLGPEPQEPPPGPPPSPA 937
L PL + P SP +P+A+P P + P L P + PP PP SP
Sbjct: 697 PSLAAPPL-------QVPPSPPASPPMSPSATPPPQAPPP---LAAPPLQVPPSPPASPP 746
Query: 938 AAPEAVPPPPAPPSYSDKGVQTPSKGTPAPLP 969
+P A PPP PP + +Q P PA LP
Sbjct: 747 MSPSATPPPRVPPLLAAPPLQVP-PSPPASLP 777
Score = 81.6 bits (200), Expect = 3e-15
Identities = 156/619 (25%), Positives = 203/619 (32%), Gaps = 109/619 (17%)
Query: 385 PGAGHPATKLP---PDSLGSFQQQHTALQGPLASADLGLAPTPSPGLDRKALAEATNGEA 441
P + AT LP P S A P A L P+P +A T
Sbjct: 318 PPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPM 377
Query: 442 RAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILGP----GEPGPQAPSRTPSPRSPAP 497
+A P Q + P + S ++A P A L G P QA T S + +P
Sbjct: 378 QAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQA---THSFLTMSP 434
Query: 498 ARVKAELSSPTPGSSPVPGELGLAGALFLP-----QYVFGPDAAPPASEILAKMSELVHS 552
+ +A L+SP+ +S P L L LP Q P +P +S + + + S
Sbjct: 435 RQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSS 494
Query: 553 RLQQGAGAGAGG-------AQTGLFPGAPKGATCFECEITFSNVNNYYVHKRLYCSGRRA 605
A Q+ L AP +T + N A
Sbjct: 495 LASHSPQAPLSSLIMPPLETQSSL---APPSLQTPPASLTTPPLENLPSLAPPPLQTASA 551
Query: 606 PEDAPAARRPKAP-PGPARAPPGQPAEPDAPRSSPGPGAREEGAGGAATPEDGAGGRGSE 664
P P P P P P +APP +P ++P P E ATP A
Sbjct: 552 PLTTPHLETPPCPAPCPLQAPP-------SPLTTPPP----ETPSSIATPPPQA------ 594
Query: 665 GSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRPAAPPGPP 724
P + + PS L PPP+ P PP
Sbjct: 595 ---PPALASPPLQGLPSPPLSPLAT----------------------PPPQAPPXLALPP 629
Query: 725 --GPAAPPAPSPAAPVRTRRRRK-----LYELHAAGAPPPPPPGHAP-APESPRPGSGSG 776
P +PPA P +P+ T + ++ L A +PPP PP AP +P + P S S
Sbjct: 630 LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSA 689
Query: 777 SGPGLAPAR--------SPGPAADGPIDLSKKPRRPLPGAPAPALADYHECTACRVSFHS 828
+ P AP P P A P+ S P P AP P A +
Sbjct: 690 TPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPP---PQAPPPLAAPPLQVPPSPP---- 742
Query: 829 LEAYLAHKKYSCPAAPPPGALGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGP 888
A S A PPP L AA PP+ P L L P P
Sbjct: 743 -----ASPPMSPSATPPPRVPPLLAAPPLQVPPSPPAS--------LPMSPLAKPPPQAP 789
Query: 889 GVEARTPADRGPSPAPAPAASPQPGSRGPRDGLGPEPQEPPPGPPPSPAAAPEAVPPPPA 948
A P PSP PA+ P P L P PP P AAP PP
Sbjct: 790 PALATPPLQALPSP---PASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSP 846
Query: 949 PPSYSDKGVQTPSKGTPAP 967
P S + + + P TP P
Sbjct: 847 PASPTLQAPRRPP--TPGP 863
Score = 79.7 bits (195), Expect = 1e-14
Identities = 161/656 (24%), Positives = 228/656 (34%), Gaps = 118/656 (17%)
Query: 385 PGAGHPATKLPPDSLGSFQQQHTALQGPLASADLGLAPTPSPGLDRKALAEATNGEARAE 444
PG+ P + P +L + PLA G+ P +A G R+
Sbjct: 30 PGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRA------GPTRSA 83
Query: 445 PLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILGPGEPGPQAPSRTPSPRSPAPARVKAEL 504
+ +S PPA+ R + + P+ PG + + P P R+ AE
Sbjct: 84 GTSSRNPASRPPASGRGERAPPAKNTSPGPV---SSPGRASGTTRPGPLGQKGLRISAEE 140
Query: 505 SSPTPGSSPVPGELGL-AGALFLPQYVFGPDAAPPASEILAKMSELVHSRLQQGAGAGAG 563
+ ++ P L AGA + GP P S +A+ S A
Sbjct: 141 TVARGKATEAPKRSALSAGA---RRDTSGPTPGTP-SPAMARRSR-------------AA 183
Query: 564 GAQTGLFPGAPKGATCFECEITFSNVNNYYVHKRLYCS--GRRAPEDAPAARRP------ 615
G + GL AP E +V++ H S RR P +RP
Sbjct: 184 GTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLS 243
Query: 616 -KAPP--GPARAPPGQPAEPDAPRSSPGPGAREEGAGGAATPEDGAGGRGSEGSQSPGSS 672
A P PAR+ P P AP P + +G P+ + + + P SS
Sbjct: 244 SSATPLSSPARSGPSARGTPRAPAHPSQP--KPKGLQALRPPQVTPPRKDAAPALGPLSS 301
Query: 673 VDDAEDDPSRTLCEAC--NIRFSRHETYTVHKRYYCASRHDPPPRRPAAPPG----PPGP 726
A PS T + T+ A+ P P+APP P P
Sbjct: 302 SPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPP 361
Query: 727 AAPPAPSP--------AAPVRTRRRRKLYELHAAGAP----PPPP--------------- 759
A PP+ +P AP + + H+ +P PP P
Sbjct: 362 ATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSP 421
Query: 760 ---PGHAPAPESPRPGSGSGSGPGLAPARSP--GPAADGPIDLSKKPRRPLPGAPAPALA 814
H+ SPR S + P PA +P P P+ L P PL + +PA++
Sbjct: 422 TLQATHSFLTMSPRQTQASLTSPS-RPASTPPDSPPLQAPLSLPASP--PLQTSLSPAVS 478
Query: 815 DYHECTACRVSFHSLEAYLAHKKYSCPAAP------PP----GALGLPAAACPYCPPNGP 864
+ ++ H L+A + +S P AP PP +L P+ P P
Sbjct: 479 P----LSSPLTIHPLQALSSLASHS-PQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTP 533
Query: 865 VRGDLLEHFRLAHGLL--LGAPLAGPGVEARTPADRGPSPAPAPAASP-----QPGSRGP 917
+L LA L APL P +E TP P PAP P +P P P
Sbjct: 534 PLENLPS---LAPPPLQTASAPLTTPHLE--TP----PCPAPCPLQAPPSPLTTPPPETP 584
Query: 918 RDGLGPEPQEPP--PGPP----PSPAAAPEAVPPPPAPPSYSDKGVQTPSKGTPAP 967
P PQ PP PP PSP +P A PPP APP + +Q P +P
Sbjct: 585 SSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASP 640
Score = 72.0 bits (175), Expect = 3e-12
Identities = 129/499 (25%), Positives = 165/499 (33%), Gaps = 142/499 (28%)
Query: 485 APSRTPSPRSPAPARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGPDAAPPASEILA 544
A +RTP+ R+P L +P P SP P P P A +L
Sbjct: 12 AAARTPAARAPG-------LLTPRPPGSPRPP----------------PPVTPAALRVLG 48
Query: 545 KMSELVHSRLQQGAGAGAGGAQTGLFPGAPKGATCFECEITFSNVNNYYVHKRLYCSGRR 604
+ L + AG G GGA + AP+ + S R
Sbjct: 49 AAGAVGRKPLAERAG-GIGGAT--IPESAPRAGPT----------------RSAGTSSRN 89
Query: 605 APEDAPAARRPKAPPGPARAPPGQPAEPDAPRSSPGPGAREEGAGGAATPEDGAGGRGSE 664
PA+ R + RAPP A +SPGP + A G P G G +
Sbjct: 90 PASRPPASGRGE------RAPP-------AKNTSPGPVSSPGRASGTTRP----GPLGQK 132
Query: 665 GSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRPAAPPGPP 724
G +R S ET + P+R A G
Sbjct: 133 G------------------------LRISAEET-------VARGKATEAPKRSALSAGAR 161
Query: 725 GPAAPPAPSPAAPVRTRRRRKLYELHAAGAP---PPPPPGHAPAP--ESPRPGSGSGSGP 779
+ P P +P RR R AAG P P P P P E PR S S
Sbjct: 162 RDTSGPTPGTPSPAMARRSR------AAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEH 215
Query: 780 GL---APARSPGPAADGPIDLSKKPRRPLPGAPAPALADYHECTACRVSFHSLEAYLAHK 836
+PA P+A G L + R L + P + + R
Sbjct: 216 STTEPSPAARRRPSAGG--GLQRPASRSLSSSATPLSSPARSGPSAR------------- 260
Query: 837 KYSCPAAPPPGALGLPAAACPYCPPN-GPVRGDLLEHFRLAHGLLLGAPLAGP---GVEA 892
P AP + P PP P R D A G L +PLA P G +A
Sbjct: 261 --GTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAP----ALGPLSSSPLATPSPSGTKA 314
Query: 893 RTPADRGPSPAPAPAASPQPGSRGPRDGLGPEPQEPPPGPPPSPAAAP--EAVPPPPA-P 949
R P P P AA+P P + P P P P PPSP+A P + +P PPA P
Sbjct: 315 R------PVPPPDNAATPLPATLPP----SPPLATPLPLAPPSPSAPPSLQTLPSPPATP 364
Query: 950 PSYSDKGVQTPSKGTPAPL 968
PS + + TP P L
Sbjct: 365 PSQAPPSMTTPPMQAPPSL 383
Score = 70.5 bits (171), Expect = 8e-12
Identities = 127/439 (28%), Positives = 142/439 (32%), Gaps = 128/439 (29%)
Query: 610 PAARRP----KAPPGPARAPPGQPAEPDAPRSSPGPGA--------REEGAGGAATPEDG 657
PAAR P PPG R PP P P A R GA R G GGA PE
Sbjct: 17 PAARAPGLLTPRPPGSPRPPP--PVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESA 74
Query: 658 ---------------------AGGRGSEG------SQSPGSSVDDAEDDPSRTLCEACNI 690
A GRG S P SS A +
Sbjct: 75 PRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGL 134
Query: 691 RFSRHETYTVHKRYYCASRHDPPPRRPAAPPGPPGPAAPPAPSPAAPVRTRRRRKLYELH 750
R S ET K P+R A G + P P +P RR R
Sbjct: 135 RISAEETVARGKA-------TEAPKRSALSAGARRDTSGPTPGTPSPAMARRSR------ 181
Query: 751 AAGAP---PPPPPGHAPAP--ESPRPGSGSGSGPGLAPARSPGPAADGPIDLSKKPRRPL 805
AAG P P P P P E PR S S P PAA RRP
Sbjct: 182 AAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTT---EPSPAAR---------RRPS 229
Query: 806 PGAPAPALADYHECTACRVSFHSLEAYLAHKKYSCPAAPPPGALGLPAA-ACPYCP-PNG 863
G R + SL + + S PA P A G P A A P P P G
Sbjct: 230 AGGGLQ-----------RPASRSLSS--SATPLSSPARSGPSARGTPRAPAHPSQPKPKG 276
Query: 864 ----------PVRGDLLEHFRLAHGLLLGAPLAGP---GVEART-----------PADRG 899
P R D A G L +PLA P G +AR PA
Sbjct: 277 LQALRPPQVTPPRKDAAP----ALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLP 332
Query: 900 PSP---APAPAASPQPGSRGPRDGLGPEPQEPPPGPPPS----PAAAP---EAVPPPPAP 949
PSP P P A P P + L P PP PPS P AP + +PP P
Sbjct: 333 PSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVP 392
Query: 950 PSYSDKGVQTPSKGTPAPL 968
S + +Q P P+PL
Sbjct: 393 HSLTSPSLQAP----PSPL 407
Score = 69.7 bits (169), Expect = 1e-11
Identities = 139/585 (23%), Positives = 191/585 (32%), Gaps = 134/585 (22%)
Query: 390 PATKLPPDSLGS--FQQQHTALQGPLASADLGLAPTPSPGLDRKALAEATNGEARAEPLA 447
P+ + PP SL + + + PL +A AP +P L+ +A PL
Sbjct: 521 PSLQTPPASLTTPPLENLPSLAPPPLQTAS---APLTTPHLETPPCPAPCPLQAPPSPL- 576
Query: 448 QNGGSSEPPAAPRSIKVEAVEEPEAA---PILGPGEPGPQAPSRTPSPRSPAPARVKAEL 504
++ PP P SI + P A P+ G P P +P TP P++P +
Sbjct: 577 ----TTPPPETPSSIATPPPQAPPALASPPLQGLPSP-PLSPLATPPPQAPPXLALPPLQ 631
Query: 505 SSPTPGSSPVPGELGL-------AGALFLPQYVFGPDAAPPASEILAKMSELVHSRLQQG 557
+ P+P +SP L A A+ L Q F P +PP V +
Sbjct: 632 APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPP-----------VQAPFSPP 680
Query: 558 AGAGAGGAQTGLFPGAPKGATCFECEITFSNVNNYYVHKRLYCSGRRAPEDAPAARRPKA 617
A + T P A ++ S +P +P+A P
Sbjct: 681 ASPPVSPSATPPSQAPPSLAA---------------PPLQVPPSPPASPPMSPSATPPPQ 725
Query: 618 PPGPARAPPGQ--PAEPDAPRSSPGPGAREEGAGGAATPEDGAGGRGSEGSQSPGSSVDD 675
P P APP Q P+ P +P SP A P + SP +S+
Sbjct: 726 APPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPP-------LQVPPSPPASL-- 776
Query: 676 AEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRPAAPPGPPGPAAPPAPSPA 735
P L + PPP+ P A PP A P P+
Sbjct: 777 ----PMSPLAK-------------------------PPPQAPPALATPPLQALPSPPASF 807
Query: 736 APVRTRRRRKLYELHAAGAPPPPPPGHAPAPESPRPGSGSGSGPGLAPARSPGPAAD--- 792
+ PPP P AP P S S AP R P P D
Sbjct: 808 PGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSV 867
Query: 793 -GP-IDLSKKPRRPLPGAPAPA-------LADYHECTACRVSFHSLEAYLAHKKYSCPAA 843
GP + L+ P P P + +P+ LA H +A L Y + + A+
Sbjct: 868 SGPRLTLALAPGPPPPPSRSPSSTLSGPDLAG-HSSSATSTP-EELRGYDSGPEGGAAAS 925
Query: 844 PPPGA--------------------LGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGA 883
PPP A G P A P+ P GP D GL
Sbjct: 926 PPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSAD---------GLCTIY 976
Query: 884 PLAGPGVEARTPADRGPSPAPAPAASPQPGSRGPRDGLGPEPQEP 928
GP E+ TPA P P+P S + G G G + P
Sbjct: 977 ETEGP--ESATPAPGALDPGPSPGTSGGKAAAGA--GAGASSRSP 1017
Score = 68.6 bits (166), Expect = 3e-11
Identities = 158/609 (25%), Positives = 191/609 (31%), Gaps = 127/609 (20%)
Query: 384 SPGAGHPATKLPPDSLGSFQQQHTALQGPLASADLGLAP----TPSPGLDRKALAEATNG 439
SP HP L + S Q ++L P LAP TP L L N
Sbjct: 482 SPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLE---NL 538
Query: 440 EARAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILGPGEPGPQAPSRTPSPRSPAPAR 499
+ A P Q +S P P +E P P+ P P P TPS + P +
Sbjct: 539 PSLAPPPLQT--ASAPLTTPH---LETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQ 593
Query: 500 VKAELSSPTPGSSPVP--GELGLAGALFLPQYVFGPDAAPPASEILAKMSELVHSRLQQG 557
L+SP P P L P P APP+ +S L
Sbjct: 594 APPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPS---- 649
Query: 558 AGAGAGGAQTGLFPGAPKGATCFECEITFSNVNNYYVHKRLYCSGRRAPEDAPAAR--RP 615
P AP + FS + V +AP PA+ P
Sbjct: 650 -------------PQAPNALAVHLLQAPFSPPPSPPV---------QAPFSPPASPPVSP 687
Query: 616 KAPPGPARAPPGQPAEPDAPRSSPGPGAREEGAGGAATPEDGAGGRGSEGSQSPGSSVDD 675
A P P++APP A P + P P A + A P + Q P S
Sbjct: 688 SATP-PSQAPPSLAAPP--LQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPAS 744
Query: 676 AEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRPAAPPGPP--GPAAPPAPS 733
PS T PPPR P PP P +PPA
Sbjct: 745 PPMSPSAT----------------------------PPPRVPPLLAAPPLQVPPSPPASL 776
Query: 734 PAAPVRTRRRRKLYELHAAGAPPPPPPGHAPAPESPRPGSGSGSGPGLAPARSPGPAADG 793
P +P+ A PP PP A P P S S PG AP P+A
Sbjct: 777 PMSPL-------------AKPPPQAPPALATPPLQALP-SPPASFPGQAPF---SPSASL 819
Query: 794 PIDLSKKPRRPLPGAPAPALADYHECTACRVSFHSLEAYLAHKKYSCPAAPPPGALGLPA 853
P+ P P AP P LA A L S PA+P A P
Sbjct: 820 PMSPLATPP---PQAP-PVLA----------------APLLQVPPSPPASPTLQAPRRPP 859
Query: 854 AACPYCPPNGP------VRGDLLEHFRLAHGLLLGAPLAGPGVEAR-TPAD-RGPSPAPA 905
P +GP G R L G LAG A TP + RG P
Sbjct: 860 TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPE 919
Query: 906 PAASPQPGSRGPRDGLGPEPQEPPPGPPPSPAAAPEA-VPPPPAPPSYSDKGVQT----- 959
A+ P P P PP + AP A +P PPA S G+ T
Sbjct: 920 GGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETE 979
Query: 960 -PSKGTPAP 967
P TPAP
Sbjct: 980 GPESATPAP 988
Score = 65.5 bits (158), Expect = 2e-10
Identities = 115/444 (25%), Positives = 137/444 (30%), Gaps = 82/444 (18%)
Query: 384 SPGAGHPATKLPPDSLGSFQQQHTALQGPLASADLGLAPTPSPGLDRKALAEATNGEARA 443
SP A P P +L Q A P AS L TPSP
Sbjct: 612 SPLATPPPQAPPXLALPPLQ----APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSP 667
Query: 444 EPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILG-------PGEPG--PQAPSRTPSPRS 494
P PPA+P + A +A P L P P P +PS TP P++
Sbjct: 668 PPSPPVQAPFSPPASP-PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA 726
Query: 495 PAPARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGPDAAPPASEILAKMSELVHSRL 554
P P P+P +SP P P PP+ MS L
Sbjct: 727 PPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPP 786
Query: 555 QQGAGAGAGGAQTGLFPGAPKGATCFECEITFSNVNNYYVHKRLYCSGRRAPEDAPAARR 614
Q Q P F + FS P A
Sbjct: 787 QAPPALATPPLQ-----ALPSPPASFPGQAPFS-------------PSASLPMSPLATPP 828
Query: 615 PKAPPGPA----RAPPGQPAEP--DAPRSSPGPGAREEGAGGAATPEDGAGGRGSEGSQS 668
P+APP A + PP PA P APR P PG P+ G + +
Sbjct: 829 PQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPG-----------PDTSVSGPRLTLALA 877
Query: 669 PGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRPAAPPGPPG--- 725
PG + PS TL S T T + +D P AA PP
Sbjct: 878 PGPPPPPSR-SPSSTLSGPDLAGHSSSATSTPEE----LRGYDSGPEGGAAASPPPDAEL 932
Query: 726 PAAPPAP---SPAAPVRTRRRRKLYELHAAGAPPPPPPGHAP-------------APESP 769
A PA PA P+ R A GAP P PP P PES
Sbjct: 933 AACHPAAWSRGPAPPLAFR--------GAPGAPLPWPPATGPGSADGLCTIYETEGPESA 984
Query: 770 RPGSGSGSGPGLAPARSPGPAADG 793
P G+ PG +P S G AA G
Sbjct: 985 TPAPGA-LDPGPSPGTSGGKAAAG 1007
Score = 58.9 bits (141), Expect = 2e-08
Identities = 145/629 (23%), Positives = 192/629 (30%), Gaps = 152/629 (24%)
Query: 463 KVEAVEEPEAAPILGPGEPGPQAPSRTPSPRSPAPARVKAELSSPTPGSSPVPGELGLAG 522
K A AA G P P R P P +PA RV ++ G P+ G G
Sbjct: 9 KAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLG--AAGAVGRKPLAERAGGIG 66
Query: 523 ALFLPQYV-------------FGPDAAPPASEILAKMSELVHSRLQQGAGAGAGGAQTGL 569
+P+ P + PPAS + ++ + G T
Sbjct: 67 GATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP 126
Query: 570 FPGAPKGATCFECEITFSNVNNYYVHKRLYCSGRRAPEDAPA--------ARRPKAPPG- 620
P KG E + +G R P ARR +A
Sbjct: 127 GPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTE 186
Query: 621 ---PARAPPGQPAEP-DAPRSS-----------PGPGARE--EGAGGAATPEDGAGGRGS 663
P AP +P P + PR S P P AR GG P + +
Sbjct: 187 VGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSA 246
Query: 664 EGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHD-PPPRRPAAP-- 720
SP S A P R H + K PPR+ AAP
Sbjct: 247 TPLSSPARSGPSARGTP----------RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL 296
Query: 721 ----------PGPPGPAAPPAPSP---AAPVRTRRRRKLYELHAAGAPPPPP-----PGH 762
P P G A P P P A P+ A PP PP P
Sbjct: 297 GPLSSSPLATPSPSGTKARPVPPPDNAATPL------------PATLPPSPPLATPLPLA 344
Query: 763 APAPESPRPGSGSGSGPGLAPARSP----GPAADGPIDLSKKPRRPLP---------GAP 809
P+P +P S P P+++P P P L P +P P
Sbjct: 345 PPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPP 404
Query: 810 AP-ALADYHECTA-------CRVSFHSLEAYLAHKKYSCPAAP---PPGA------LGLP 852
+P AL+ T+ SF ++ + P+ P PP + L LP
Sbjct: 405 SPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLP 464
Query: 853 AA---ACPYCPPNGPVRGDLLEHFRLAHGLLLG----APLAG---PGVEART-------- 894
A+ P P+ L H A L APL+ P +E ++
Sbjct: 465 ASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQ 524
Query: 895 ---------PADRGPSPAPAPAASPQPGSRGPRDGLGPEPQEPPPGPPPSPAAAPE---- 941
P + PS AP P + P P P P PPSP P
Sbjct: 525 TPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETP 584
Query: 942 ---AVPPPPAPPSYSDKGVQTPSKGTPAP 967
A PPP APP+ + P +G P+P
Sbjct: 585 SSIATPPPQAPPALA----SPPLQGLPSP 609
Score = 42.4 bits (98), Expect = 0.002
Identities = 76/317 (23%), Positives = 102/317 (32%), Gaps = 57/317 (17%)
Query: 385 PGAGHPATKLPPDSLGSFQQQHTALQGP-----LASADLGLAPTPSPGLDRKALAEATNG 439
P P ++PP S +A P LA+ L + P+P L LA+
Sbjct: 728 PPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPP-- 785
Query: 440 EARAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILGP-GEPGPQAPSRTPSPRSPAPA 498
+A P P+ P S +A P A+ + P P PQAP +P P
Sbjct: 786 -PQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPP 844
Query: 499 RVKAELSSPTPGSSPVPG-ELGLAGALFLPQYVFGPDAAP---PASEI----LAKMSELV 550
A + P P PG + ++G GP P P+S + LA S
Sbjct: 845 SPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSA 904
Query: 551 HSRLQQGAGAGAGGAQTGLFPGAPKGATCFECEITFSNVNNYYVHKRLYCSGRRAP---E 607
S ++ G +G + G P A C H + G P
Sbjct: 905 TSTPEELRGYDSG-PEGGAAASPPPDAELAAC------------HPAAWSRGPAPPLAFR 951
Query: 608 DAPAARRPKAPP----------------GPARAPPGQPAEPDAPRSSPGPGAREEGAGGA 651
AP A P P GP A P P A P PG +GG
Sbjct: 952 GAPGAPLPWPPATGPGSADGLCTIYETEGPESATPA----PGALDPGPSPGT----SGGK 1003
Query: 652 ATPEDGAGGRGSEGSQS 668
A GAG Q+
Sbjct: 1004 AAAGAGAGASSRSPKQA 1020
Score = 39.7 bits (91), Expect = 0.014
Identities = 65/256 (25%), Positives = 80/256 (31%), Gaps = 34/256 (13%)
Query: 752 AGAPPPPPPGHAPAPESPRPGSGSGSGPGLAPARSPGPAADGPIDLSKKPRRP--LPGAP 809
AGA P AP +PRP P + PA A G + R + GA
Sbjct: 10 AGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGAT 69
Query: 810 APALADYHECTACRVSFHSLEAYLAHKKYSCPAAPP-----PGALGLPAAACPYCPPNGP 864
P A T + A APP PG + P A P GP
Sbjct: 70 IPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP-GP 128
Query: 865 VRGDLLE---HFRLAHGLLLGAP-----LAGPGVEARTPADRGPSPA------------- 903
+ L +A G AP AG + P PSPA
Sbjct: 129 LGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVG 188
Query: 904 ---PAPAASPQPGSRGPRDGLGPEPQEPPPGPPPSPAAAPEAVPPPPAPPSYSDKGVQTP 960
PAP+A P+P + GPR + + P P+ P A P S S TP
Sbjct: 189 LPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP 248
Query: 961 --SKGTPAPLPNGNHR 974
S P G R
Sbjct: 249 LSSPARSGPSARGTPR 264
Score = 37.4 bits (85), Expect = 0.071
Identities = 49/190 (25%), Positives = 63/190 (33%), Gaps = 50/190 (26%)
Query: 33 MEQKATAPEAPSPPSADVNSPPPLPPPTSPGGPKELEGQEPEPR--------PTEEEPGS 84
M AT P PP A +PP PP+ P P P PR P + P
Sbjct: 716 MSPSATPPPQAPPPLA---APPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSP 772
Query: 85 PWSGPDELEPVVQDGQRRIRARLSLATGLSWGPFHGSVQTRASSPRQAEPSPALTLLLVD 144
P S P + P+ + +A +LAT P AS P QA SP+ +L +
Sbjct: 773 PASLP--MSPLAKPPP---QAPPALAT----PPLQALPSPPASFPGQAPFSPSASLPMSP 823
Query: 145 EACWLRTLPQALTEAEANTEIHRKDDALWCRVTKPVPAGGLLSVLLTAEPHSTPGHPVKK 204
A T P A +L+ L P S P P +
Sbjct: 824 LA------------------------------TPPPQAPPVLAAPLLQVPPSPPASPTLQ 853
Query: 205 EPAEPTCPAP 214
P P P P
Sbjct: 854 APRRPPTPGP 863
Score = 36.6 bits (83), Expect = 0.12
Identities = 45/171 (26%), Positives = 54/171 (31%), Gaps = 25/171 (14%)
Query: 40 PEAPSPPSADVNSPPPLP-PPTSPGGPKELEGQEP-EPRPTEEEPGSPWSGPDELEPVVQ 97
P P+ P+ PP P P TS GP+ P P P P S SGPD +
Sbjct: 844 PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPD-----LA 898
Query: 98 DGQRRIRARLSLATGLSWGPFHGSVQTRASSPRQAEPSPALTLLLVDEACWLR--TLPQA 155
+ G GP G+ A P P L A W R P A
Sbjct: 899 GHSSSATSTPEELRGYDSGPEGGAA---------ASPPPDAELAACHPAAWSRGPAPPLA 949
Query: 156 LTEAEANTEIHRKDDALWCRVTKPVPAGGLLSVLLTAEPHSTPGHPVKKEP 206
A W T P A GL ++ T P S P +P
Sbjct: 950 FRGAPG-------APLPWPPATGPGSADGLCTIYETEGPESATPAPGALDP 993
Score = 35.4 bits (80), Expect = 0.27
Identities = 53/214 (24%), Positives = 78/214 (36%), Gaps = 36/214 (16%)
Query: 384 SPGAGHPATKLP------PDSLG---SFQQQHTALQGPLASADLGLAPTPSPGLDRKALA 434
+PG P ++ P PD G S L+G + + G A +P P + A
Sbjct: 877 APGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACH 936
Query: 435 EATNGEARAEPLAQNGG---------SSEPPAAPRSIKVEAVEEPEAA-PILGPGEPGPQ 484
A A PLA G ++ P +A + E PE+A P G +PGP
Sbjct: 937 PAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGP- 995
Query: 485 APSRTPSPRSPAPARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGPDAAPPASEILA 544
SP + KA + SS P + L + G A +L+
Sbjct: 996 ---------SPGTSGGKAAAGAGAGASSRSPKQARLG------ELPLGALQASVVQHLLS 1040
Query: 545 KMSELVHSR-LQQGAGAGAGGAQTGLFPGAPKGA 577
+ L + G+G G GGA+ G G + A
Sbjct: 1041 RTLLLAAAEGAAGGSGGGPGGAEGGGVTGGARAA 1074
Score = 33.9 bits (76), Expect = 0.79
Identities = 22/65 (33%), Positives = 30/65 (46%), Gaps = 2/65 (3%)
Query: 34 EQKATAPEAPSPPSADVNSPPPLPPPTSPGGPKELEG-QEPEPRPTEEEPGSPWSGPDEL 92
+ AT A PPS + +P PL PP SP P L+ P P + P S + P +
Sbjct: 321 DNAATPLPATLPPSPPLATPLPLAPP-SPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQA 379
Query: 93 EPVVQ 97
P +Q
Sbjct: 380 PPSLQ 384
Score = 30.4 bits (67), Expect = 8.7
Identities = 40/173 (23%), Positives = 58/173 (33%), Gaps = 37/173 (21%)
Query: 43 PSPPSADVNSPPPLPPPTSPGGPKELEGQEPEPRPTEEEPGSPWSGPDELEPVVQDGQRR 102
PSPP + + +PPP PP L + P P P SP + P P
Sbjct: 607 PSPPLSPLATPPPQAPP-----XLALPPLQAPPSPPASPPLSPLATPSPQAP-------- 653
Query: 103 IRARLSLATGLSWGPFHGSVQTRASSPRQAEPSPALTLLLVDEACWLRTLPQALTEAEAN 162
+LA L PF +P SP ++ P A ++A
Sbjct: 654 ----NALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS-------------PSATPPSQAP 696
Query: 163 TEIHRKDDALWCRVTKPVPAGGLLSVLLTAEPHSTP---GHPVKKEPAEPTCP 212
+ A +V PA +S T P + P P++ P+ P P
Sbjct: 697 PSL----AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASP 745
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 106 bits (265), Expect = 1e-22
Identities = 150/579 (25%), Positives = 197/579 (34%), Gaps = 90/579 (15%)
Query: 408 ALQGPLASADLGLAPTPSPGLDRKALAEATNGEARAEPLAQNGGSSEPPAAPRSIKVEAV 467
A + P A A L P P PG R A L G P A R+ +
Sbjct: 13 AARTPAARAPGLLTPRP-PGSPRPPPPVTP---AALRVLGAAGAVGRKPLAERAGGIGGA 68
Query: 468 EEPEAAPILGPGEPGPQAPSRTPSPRSPAPARVK----AELSSPTPGSSPV-------PG 516
PE+AP GP + SR P+ R PA R + A+ +SP P SSP PG
Sbjct: 69 TIPESAPRAGPTRSAGTS-SRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPG 127
Query: 517 ELGLAGALFLPQYVFGPDAAPPASEILAKMSELVHSRLQQGAGAGAGGAQTGLFPGAPKG 576
LG G A E +A+ + + + AGA +G PG P
Sbjct: 128 PLGQKGLRI------------SAEETVAR-GKATEAPKRSALSAGARRDTSGPTPGTPSP 174
Query: 577 ATCFECEITFSNVNNYYVHKRLYCSGRRAPEDAPAARRPKAPPGPARAPPGQPAEPDAPR 636
A + V P AP+AR P+ P R +E
Sbjct: 175 AMARRSRAAGTEVG--------------LPRPAPSAR-PRPPTEGPRKSVSSASEHSTTE 219
Query: 637 SSPGPGAREEGAGGAATPEDGAGGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHE 696
SP R GG P + + SP S A P R H
Sbjct: 220 PSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTP----------RAPAHP 269
Query: 697 TYTVHKRYYCASRHD-PPPRRPAAPPGPPGPAAPPA-PSPAAPVRTRRRRKLYELHAAGA 754
+ K PPR+ AAP P ++P A PSP+A ++++ A
Sbjct: 270 SQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQ------------A 317
Query: 755 PPPPPPGHAPAPESPRPGSGSGSGPGLAPARSPGPAADGPIDLSKKPRRPLPGAPAPALA 814
PP P +P S + P P P+A + P P +L
Sbjct: 318 PPT-------LPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLG 370
Query: 815 DYHECTACRVSFHSLEAYLAHKKYSCPAAPPPGA---LGLPAAACPYCPPNGPVRGDLLE 871
+ + ++L S A PPP A L LP P PP P L
Sbjct: 371 S--------PTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLAT 422
Query: 872 HFRLAHGLLLGAPLAGPGVEARTPADRGP-SPAPAPAASPQ--PGSRGPRDGLGPEPQEP 928
A L L P +P + P SP +P SP P S+ P L P +
Sbjct: 423 PSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAP-PSLAAPPLQV 481
Query: 929 PPGPPPSPAAAPEAVPPPPAPPSYSDKGVQTPSKGTPAP 967
PP PP SP +P A PPP APP + +Q AP
Sbjct: 482 PPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAP 520
Score = 85.5 bits (210), Expect = 2e-16
Identities = 152/680 (22%), Positives = 215/680 (31%), Gaps = 170/680 (25%)
Query: 385 PGAGHPATKLPPDSLGSFQQQHTALQGPLASADLGLAPTPSPGLDRKALAEATNGEARAE 444
PG+ P + P +L + PLA G+ P +A G R+
Sbjct: 30 PGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRA------GPTRSA 83
Query: 445 PLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILGPGE------PGP--------------- 483
+ +S PPA+ R + + P+ PG PGP
Sbjct: 84 GTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVA 143
Query: 484 -----QAPSRT------------PSPRSPAPARVKAE--------LSSPTPGSSPVPGEL 518
+AP R+ P+P +P+PA + L P P + P P
Sbjct: 144 RGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTE 203
Query: 519 GLAGALFLPQYVFGPDAAP--------------PASEILAKMSELVHSRLQQGAGA-GAG 563
G ++ + +P PAS L+ + + S + G A G
Sbjct: 204 GPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTP 263
Query: 564 GAQTGLFPGAPKGATCFEC-EITFSNVNNYYVHKRLYCSGRRAPEDAPAARRPKAPPGPA 622
A PKG ++T + AP P + P A P P+
Sbjct: 264 RAPAHPSQPKPKGLQALRPPQVTPPRKD-------------AAPALGPLSSSPLATPSPS 310
Query: 623 -----RAPPGQPAEPDA---------------PRSSPGPGAREEGAGGAATPEDGAGGRG 662
+APP PA P + P S P + + A P G
Sbjct: 311 AALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLG 370
Query: 663 SEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRPAAPPG 722
S Q+ S + P T PPP+ P A
Sbjct: 371 SPTLQATHSFLPSPPLSPLAT----------------------------PPPQAPPALAL 402
Query: 723 PP--GPAAPPAPSPAAPVRTRRRRK-----LYELHAAGAPPPPPPGHAP-APESPRPGSG 774
PP P +PPA P +P+ T + ++ L A +PPP PP AP +P + P S
Sbjct: 403 PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSP 462
Query: 775 SGSGPGLAPAR--------SPGPAADGPIDLSKKPRRPLPGAPAPALADYHECTACRVSF 826
S + P AP P P A P+ S P P AP P A +
Sbjct: 463 SATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPP---PQAPPPLAAPPLQLA------ 513
Query: 827 HSLEAYLAHKKYSCPAAPPPGALGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLA 886
P PP P A P P + P + L L P
Sbjct: 514 ------------KPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQ 561
Query: 887 GPGVEARTPADRGPSPAPAPA--ASPQPGSRGPRDGL-GPE-PQEPPPGPPPSPAAAPEA 942
P V A PSP +P A +P + GP + GP PGPPP P+ +P +
Sbjct: 562 APPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSS 621
Query: 943 VPPPPAPPSYSDKGVQTPSK 962
P +S TP +
Sbjct: 622 TLSGPDLAGHSSSATSTPEE 641
Score = 74.3 bits (181), Expect = 5e-13
Identities = 150/602 (24%), Positives = 200/602 (33%), Gaps = 116/602 (19%)
Query: 390 PATKLPPDSLGSFQQQHTALQGPLA----SADLGLAPTPSPGLDRKAL---AEATNG-EA 441
P T+ P S+ S + T P A SA GL S L A + A +G A
Sbjct: 200 PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSA 259
Query: 442 RAEPLAQNGGSSEPPAAPRSIKVEAVEEP--EAAPILGPGEPGPQAPSRTPSPRSPAPAR 499
R P A S P ++++ V P +AAP LGP P A TPSP + ++
Sbjct: 260 RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLA---TPSPSAALQSQ 316
Query: 500 VKAELSSPTPGSSPVPGELGLAGALFLPQYVFGPDAAPPASEILAKMSELVHSRLQQGAG 559
L + TP SS + +L L P +APP+ + L S+ G
Sbjct: 317 APPTLPA-TPHSSSLTCQLATPLPLAPPS-----PSAPPSLQTLPSPPATPPSQATTSLG 370
Query: 560 AGAGGAQTGLFPGAPKGATCFECEITFSNVNNYYVHKRLYCSGRRAPEDAPAARRP--KA 617
+ A P P L P+ PA P +A
Sbjct: 371 SPTLQATHSFLPSPP-----------------------LSPLATPPPQAPPALALPPLQA 407
Query: 618 PPGPARAPPGQPAEPDAPRSSPGPGAREEGAGGAATPEDGAGGRGSEGSQSPGS-SVDDA 676
PP P +PP P +P++ A + P S + P S S
Sbjct: 408 PPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPP 467
Query: 677 EDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRP---AAPP---GPPGPAAPP 730
P + S + + + PPP+ P AAPP P P APP
Sbjct: 468 SQAPPSLAAPPLQVPPSPPASPPM------SPSATPPPQAPPPLAAPPLQLAKPPPQAPP 521
Query: 731 A---------PSPAAPVRTRRR---RKLYELHAAGAPPPPPPGHAPAPESPRPGSGSGSG 778
A PSP A + + PPP P AP P S S
Sbjct: 522 ALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASP 581
Query: 779 PGLAPARSPGPAAD----GP-IDLSKKPRRPLPGAPAPA-------LADYHECTACRVSF 826
AP R P P D GP + L+ P P P + +P+ LA H +A
Sbjct: 582 TLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAG-HSSSATSTP- 639
Query: 827 HSLEAYLAHKKYSCPAAPPPGA--------------------LGLPAAACPYCPPNGPVR 866
L Y + + A+PPP A G P A P+ P GP
Sbjct: 640 EELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGS 699
Query: 867 GDLLEHFRLAHGLLLGAPLAGPGVEARTPADRGPSPAPAPAASPQPGSRGPRDGLGPEPQ 926
D GL GP E+ TPA P P+P S + G G G +
Sbjct: 700 AD---------GLCTIYETEGP--ESATPAPGALDPGPSPGTSGGKAAAGA--GAGASSR 746
Query: 927 EP 928
P
Sbjct: 747 SP 748
Score = 45.4 bits (106), Expect = 3e-04
Identities = 75/299 (25%), Positives = 97/299 (32%), Gaps = 53/299 (17%)
Query: 384 SPGAGHPATKLPPDSLGSFQQQHTALQGPLASADLGLAPTPSPGLDRKALAE-ATNGEAR 442
SP A P PP + Q Q P A A L PSP A + +
Sbjct: 492 SPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLP 551
Query: 443 AEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILGPGEPGPQAPSRTPSPRSPAPARVKA 502
PLA + PP AP + ++ P + P P QAP R P+P
Sbjct: 552 MSPLA-----TPPPQAPPVLAAPLLQVPPSP----PASPTLQAPRRPPTPGPDTSVSGPR 602
Query: 503 ELSSPTPGSSPVPGELGLAGALFLPQYVFGPDAAPPASEILAKMSELVHSRLQQGAGAGA 562
+ PG P P + GPD A +S + EL +G +G
Sbjct: 603 LTLALAPGPPPPPSRSP-------SSTLSGPDLAGHSSSATSTPEEL------RGYDSGP 649
Query: 563 GGAQTGLFPGAPKGATCFECEITFSNVNNYYVHKRLYCSGRRAPEDAPAARRPKAP-PGP 621
G P + A C H + G P A P AP P P
Sbjct: 650 EGGAAASPPPDAELAAC---------------HPAAWSRGPAPPLAFRGA--PGAPLPWP 692
Query: 622 ARAPPGQP------AEPDAPRS-SPGPGAREEG-----AGGAATPEDGAGGRGSEGSQS 668
PG E + P S +P PGA + G +GG A GAG Q+
Sbjct: 693 PATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQA 751
Score = 39.7 bits (91), Expect = 0.014
Identities = 65/256 (25%), Positives = 80/256 (31%), Gaps = 34/256 (13%)
Query: 752 AGAPPPPPPGHAPAPESPRPGSGSGSGPGLAPARSPGPAADGPIDLSKKPRRP--LPGAP 809
AGA P AP +PRP P + PA A G + R + GA
Sbjct: 10 AGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGAT 69
Query: 810 APALADYHECTACRVSFHSLEAYLAHKKYSCPAAPP-----PGALGLPAAACPYCPPNGP 864
P A T + A APP PG + P A P GP
Sbjct: 70 IPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP-GP 128
Query: 865 VRGDLLE---HFRLAHGLLLGAP-----LAGPGVEARTPADRGPSPA------------- 903
+ L +A G AP AG + P PSPA
Sbjct: 129 LGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVG 188
Query: 904 ---PAPAASPQPGSRGPRDGLGPEPQEPPPGPPPSPAAAPEAVPPPPAPPSYSDKGVQTP 960
PAP+A P+P + GPR + + P P+ P A P S S TP
Sbjct: 189 LPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP 248
Query: 961 --SKGTPAPLPNGNHR 974
S P G R
Sbjct: 249 LSSPARSGPSARGTPR 264
Score = 36.6 bits (83), Expect = 0.12
Identities = 45/171 (26%), Positives = 54/171 (31%), Gaps = 25/171 (14%)
Query: 40 PEAPSPPSADVNSPPPLP-PPTSPGGPKELEGQEP-EPRPTEEEPGSPWSGPDELEPVVQ 97
P P+ P+ PP P P TS GP+ P P P P S SGPD +
Sbjct: 575 PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPD-----LA 629
Query: 98 DGQRRIRARLSLATGLSWGPFHGSVQTRASSPRQAEPSPALTLLLVDEACWLR--TLPQA 155
+ G GP G+ A P P L A W R P A
Sbjct: 630 GHSSSATSTPEELRGYDSGPEGGAA---------ASPPPDAELAACHPAAWSRGPAPPLA 680
Query: 156 LTEAEANTEIHRKDDALWCRVTKPVPAGGLLSVLLTAEPHSTPGHPVKKEP 206
A W T P A GL ++ T P S P +P
Sbjct: 681 FRGAPG-------APLPWPPATGPGSADGLCTIYETEGPESATPAPGALDP 724
Score = 35.8 bits (81), Expect = 0.21
Identities = 47/181 (25%), Positives = 59/181 (32%), Gaps = 29/181 (16%)
Query: 39 APEAPSPPSADVNSP--PPLPPPTSPGGPKELEGQEPEPRPTEEEPGSPWSGP---DELE 93
AP +P PPS V +P PP PP SP + P + P SP + P
Sbjct: 438 APFSP-PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSAT 496
Query: 94 PVVQDGQRRIRARLSLATGLSWGPFHGSVQTRASSPRQAEPSPALTLLLVDEACWLRTLP 153
P Q L LA P A+ P QA PSP + +LP
Sbjct: 497 PPPQAPPPLAAPPLQLAKPPPQAP-----PALATPPLQALPSPPASFPGQAPFSPSASLP 551
Query: 154 QALTEAEANTEIHRKDDALWCRVTKPVPAGGLLSVLLTAEPHSTPGHPVKKEPAEPTCPA 213
+ T P A +L+ L P S P P + P P P
Sbjct: 552 MSPL------------------ATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPG 593
Query: 214 P 214
P
Sbjct: 594 P 594
Score = 35.8 bits (81), Expect = 0.21
Identities = 55/212 (25%), Positives = 77/212 (36%), Gaps = 38/212 (17%)
Query: 384 SPGAGHPATKLP------PDSLG---SFQQQHTALQGPLASADLGLAPTPSPGLDRKALA 434
+PG P ++ P PD G S L+G + + G A +P P + A
Sbjct: 608 APGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACH 667
Query: 435 EATNGEARAEPLAQNGG---------SSEPPAAPRSIKVEAVEEPEAA-PILGPGEPGPQ 484
A A PLA G ++ P +A + E PE+A P G +PGP
Sbjct: 668 PAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGP- 726
Query: 485 APSRTPSPRSPAPARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGPDAAPPASEILA 544
SP + KA + SS P + L G L P A AS +
Sbjct: 727 ---------SPGTSGGKAAAGAGAGASSRSPKQARL-GEL--------PLGALQASVVQH 768
Query: 545 KMSELVHSRLQQGAGAGAGGAQTGLFPGAPKG 576
+S + +GA G+GG G G G
Sbjct: 769 LLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTG 800
Score = 31.6 bits (70), Expect = 3.9
Identities = 31/108 (28%), Positives = 39/108 (36%), Gaps = 21/108 (19%)
Query: 36 KATAPEAPSPPSADVNSPPPLPPPTSPGGPKELEGQEPEPRPTEEEPGSPWSGPDELEPV 95
+AT PSPP + + +PPP PP L + P P P SP + P P
Sbjct: 375 QATHSFLPSPPLSPLATPPPQAPPA-----LALPPLQAPPSPPASPPLSPLATPSPQAP- 428
Query: 96 VQDGQRRIRARLSLATGLSWGPF----HGSVQTRASSPRQAEPSPALT 139
+LA L PF VQ S P SP+ T
Sbjct: 429 -----------NALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSAT 465
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 105 bits (263), Expect = 2e-22
Identities = 163/629 (25%), Positives = 201/629 (31%), Gaps = 96/629 (15%)
Query: 390 PATKLPPDSLGSFQQQHTA--LQGPLASADLGLAPTPSPGLD-RKALAEATNGEARAEPL 446
P TK PP GS L P++ + P S K T+ P
Sbjct: 803 PQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPK 862
Query: 447 AQNGGSSEPPAAPRSIKVEAVEEPEAA------PILGPGEPGP-QAPSRTPSPRSPAPAR 499
S+ P +P+ + + E P + P GP P P QAP+ + + SP AR
Sbjct: 863 GAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKAR 922
Query: 500 V----KAELSSPTPGSSPVPGELGLAG-----ALFLPQYVFGPDAAPPASEILAKMSELV 550
K +SP+P +P P A P++ P AA P S +
Sbjct: 923 ATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSP 982
Query: 551 HSRLQQGAG---AGAGGAQTGLFPGAPKGATCFECEITFSNVNNYYVHKRLYCSGRRAPE 607
A + GG T GAP +T + P
Sbjct: 983 KGAPTPPAATPPSPKGGPATPSPKGAPTPPA-----VTPPSPKGSPAATPFPKGASTPPA 1037
Query: 608 DAPAARRPKAPPGPARAPPGQPAEPDAPRSSPGPGAREEGAGGAATPEDGA--GGRGSEG 665
P + PK P P G P P A SP G GA TP +G
Sbjct: 1038 ATPPS--PKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPA 1095
Query: 666 SQSP-GSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRPAA-PPGP 723
+ SP G+ + A PS K H P PAA PP P
Sbjct: 1096 TPSPKGAPMPPAATPPSP-------------------KGGLATPPHKGAPTTPAATPPSP 1136
Query: 724 PGPAAPPAP--SPAAPVRTRRRRKLYELHAAGAPPPPPPGH----APAPESPRPGSGSGS 777
G A P P +P P T K G PPP G A P SP+ G + S
Sbjct: 1137 KGGLATPPPKGAPTTPAATPPSPK------GGLATPPPKGAPTTPAATPPSPKGGLATPS 1190
Query: 778 GPGL--APARSPGPAADGPIDLSKKPRRPLPGAPAPALADYHECTACRVSFHSLEAYLAH 835
G PA +P G S K P A P+ L
Sbjct: 1191 PKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKG------------GLATPSPK 1238
Query: 836 KKYSCPAAPPPGALGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGPGVEARTP 895
+ PAA PP G PA PP G L GL P TP
Sbjct: 1239 GAPTTPAATPPSPKGGPATP----PPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTP 1294
Query: 896 ADRGPSPAPAPAASPQPGSRGPRDGLGPEPQEPPPGPPPSPAAAPEAVPPP--------P 947
PSP PA SP G+ P P P+ P PPP A P AV PP P
Sbjct: 1295 ----PSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLP 1350
Query: 948 APPSYSDKGVQTPS--KGTPAPLPNGNHR 974
A S G TPS +G P +H+
Sbjct: 1351 ATTPSSKGGPTTPSSKEGPTPPAATPSHK 1379
Score = 100 bits (248), Expect = 9e-21
Identities = 151/615 (24%), Positives = 194/615 (31%), Gaps = 116/615 (18%)
Query: 390 PATKLPPDSLGSFQQQHTALQGPLASADLGLAPTPSPGLDRKALAEATNGEARAEPLAQN 449
PAT P + + + A G+ +PSP + A P +
Sbjct: 900 PATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSP--------KGAPTPPAATPPSPK 951
Query: 450 GGSSEPPAAPRSIKVEAVEEPEAAPILGPGEPGPQAPSRTPSPRSPAPARVKAELSSPTP 509
GG + P +P+ A P A P G P +P P+P + P K ++P+P
Sbjct: 952 GGPATP--SPKW----APTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSP 1005
Query: 510 GSSPVPGEL------GLAGALFLPQYVFGPDAAPPASEILAKMSELVHSRLQQGAG---- 559
+P P + G A P+ P AA P S + L +GA
Sbjct: 1006 KGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSP----KGSPAATPLPKGAPTTPA 1061
Query: 560 ----AGAGGAQTGLFPGAPKGATCFECEITFSNVNNYYVHKRLYCSGRRAPEDAPAARRP 615
+ GG T GAP S + AP P A P
Sbjct: 1062 ATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATP---------SPKGAP--MPPAATP 1110
Query: 616 KAPPGPARAPP--GQPAEPDAPRSSPGPGAREEGAGGA-----ATPEDGAGGRGSEGSQS 668
+P G PP G P P A SP G GA ATP GG + +
Sbjct: 1111 PSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKG 1170
Query: 669 PGSSVDDAEDDPSRTLCEAC--NIRFSRHETYTVHKRYYCASRHDPPPRRPAA-PPGPPG 725
++ P L + T K P PAA PP P G
Sbjct: 1171 APTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKG 1230
Query: 726 PAAPPAP--SPAAPVRTRRRRKLYELHAAGAPPPPPPGHAPAPESPRPGSGSGSGPGLAP 783
A P+P +P P T K G P PPP AP P + P S G
Sbjct: 1231 GLATPSPKGAPTTPAATPPSPK-------GGPATPPPKGAPTPPAATPPSLKGGLATPPH 1283
Query: 784 ARSPGPAADGPIDLSKKPRRPLP-GAPAPALADYHECTACRVSFHSLEAYLAHKKYSCPA 842
+P PA P P P GAP P PA
Sbjct: 1284 KGAPNPAVVTPPSPKGGPATSPPKGAPTP-----------------------------PA 1314
Query: 843 APPPGALGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGPGVEARTPADRGPSP 902
A PP G P P P P + +P P + A TP+ +G
Sbjct: 1315 ATPPSPKGSPGTPPPKGAPTPPA-------------VTPPSPKGTPTLPATTPSSKGGPT 1361
Query: 903 APAPAASPQPGSRGPRDGLGPEPQEP----------PPGPPPSPAAAPEAVPPPPAPPSY 952
P+ P P + P GP P P G P SPA P + PA P
Sbjct: 1362 TPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATP-V 1420
Query: 953 SDKGVQTPSKGTPAP 967
+ +G TPSKG P
Sbjct: 1421 TREGAATPSKGDLTP 1435
Score = 90.5 bits (223), Expect = 7e-18
Identities = 159/632 (25%), Positives = 199/632 (31%), Gaps = 141/632 (22%)
Query: 376 PGSKGEIYSP---GAGHPATKLPPDSLGSFQQQHTALQGPLASADLGLAPTPSPGLDRKA 432
P KG +P GA P PP G GP + G APTP
Sbjct: 971 PSPKGGPATPSPKGAPTPPAATPPSPKG----------GPATPSPKG-APTPPA-----V 1014
Query: 433 LAEATNGEARAEPLAQNGGSSEPPAAPRSIKVE--AVEEPEAAPI-----LGPGEPGPQA 485
+ G A P + G S+ P A P S K A P+ AP L + GP
Sbjct: 1015 TPPSPKGSPAATPFPK-GASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPAT 1073
Query: 486 PSRTPSPRSPA--PARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGPDAAPPASEIL 543
PS +P PA P K ++P+P +P+P P A PP+ +
Sbjct: 1074 PSLKGAPTPPAATPPSPKGGPATPSPKGAPMP-----------------PAATPPSPK-- 1114
Query: 544 AKMSELVHSRLQQGAGAGAGGAQTGLFPGAPKGATCFECEITFSNVNNYYVHKRLYCSGR 603
++ H A + GL PKGA
Sbjct: 1115 GGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPT------------------------ 1150
Query: 604 RAPEDAPAARRPKAPPGPARAPP-GQPAEPDAPRSSPGPGAREEGAGGA-----ATPEDG 657
PAA P G A PP G P P A SP G GA ATP
Sbjct: 1151 -----TPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSP 1205
Query: 658 AGGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRP 717
GG + + G+ A PS K P P
Sbjct: 1206 KGGLATPSPK--GAPTTPAATPPSP-------------------KGGLATPSPKGAPTTP 1244
Query: 718 AAPPGPP--GPAAPP---APSPAAPVRTRRRRKLYELHAAGAPPPP-------------- 758
AA P P GPA PP AP+P A + L GAP P
Sbjct: 1245 AATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATS 1304
Query: 759 PPGHAPAPESPRPGSGSGSGPGLAPAR-SPGPAADGPIDLSKKPRRPLPGAPAPALADYH 817
PP AP P + P S GS PG P + +P P A P P P A P+
Sbjct: 1305 PPKGAPTPPAATPPSPKGS-PGTPPPKGAPTPPAVTPPSPKGTPTLP---ATTPSSKGGP 1360
Query: 818 ECTACRVSFHSLEAYLAHKKYSCPAAPPPGALGLPAAACPYCPPNGPVRGDLLEHFRLAH 877
+ + A +HK PA PP PA P P P L+
Sbjct: 1361 TTPSSKEGPTPPAATPSHK--GGPAMTPPSPKRGPAIPSPKGDPTSPAV------IPLSP 1412
Query: 878 GLLLGAPLAGPGVEARTPADRGPSPAPAPAASPQPGSRGPRDGLGPEPQEPPP-GPPPSP 936
P+ G + D P + P + P+ G P P G P P
Sbjct: 1413 KKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGG----PATPSSKGDPTLP 1468
Query: 937 AAAPEAVPPPPAPPSYSDKGVQTPSKGTPAPL 968
A P + PPAP + + TPAP+
Sbjct: 1469 AVTPPSPKEPPAPKQVATSSSPKKAPATPAPM 1500
Score = 85.1 bits (209), Expect = 3e-16
Identities = 153/636 (24%), Positives = 207/636 (32%), Gaps = 94/636 (14%)
Query: 376 PGSKGEIYSP---GAGHPATKLPPDSLGSFQQQHTALQGPLASADLGLAPTPSPGLDRKA 432
P KG +P GA P PP G T + P+P GL
Sbjct: 1088 PSPKGGPATPSPKGAPMPPAATPPSPKGGLA---TPPHKGAPTTPAATPPSPKGGLATPP 1144
Query: 433 LAEATNGEARAEPLAQNGGSSEPP--------AAPRSIKVE-AVEEPEAAPILGPGEP-G 482
A A P + G ++ PP A P S K A P+ AP P
Sbjct: 1145 PKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPS 1204
Query: 483 PQAPSRTPSPR----SPA--PARVKAELSSPTPGSSPV------PGELGLAGALFLPQYV 530
P+ TPSP+ +PA P K L++P+P +P P G A P+
Sbjct: 1205 PKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKG-GPATPPPKGA 1263
Query: 531 FGPDAAPPASEILAKMSELVHSRLQQGAGAGAGGAQTGLFPGAPKGATCFECEITFSNVN 590
P AA P S + ++ H A + G PKGA S
Sbjct: 1264 PTPPAATPPS-LKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPS--- 1319
Query: 591 NYYVHKRLYCSGRRAPEDAPAARRPK-APPGPARAPPGQPAEPDAPRSSPG-------PG 642
P+ +P PK AP PA PP P P ++P P
Sbjct: 1320 ---------------PKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPS 1364
Query: 643 AREEGAGGAATPEDGAGGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHK 702
++E AATP G + S G ++ + DP+ + +
Sbjct: 1365 SKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPK----------- 1413
Query: 703 RYYCASRHDPPPRRPAAPPGPPGPAAPPAPSPA----APVRTRRRRKLYELHAAGAPP-- 756
+ P R AA P G PPA +P AP + + + G P
Sbjct: 1414 ----KAPATPVTREGAATPSK-GDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLP 1468
Query: 757 ---PPPPGHAPAPESPRPGSGSGSGPGLAPARSPGPAADGPIDLSKKPRRPLPGAPAPAL 813
PP P PAP+ S P PA P I S K P + +
Sbjct: 1469 AVTPPSPKEPPAPKQVATSSSPKKAPA-TPAPMGAPTLPAVIPSSPKEVPATPSSRRDPI 1527
Query: 814 ADYHECTACRVSFHSLEAYLAHKKYSCPAAPPPGALGLPAAACPYCPPNGPVRGDLLEHF 873
A TA +S + + PA P PA P P P +
Sbjct: 1528 AP----TATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPP 1583
Query: 874 RLAHGLLLGAPLAGPGVEARTPADRGPSPAPAP---AASPQPGSRGPRDGLGPEPQEPPP 930
+ GAP P PA PSP AP A +P +GP P P+ P
Sbjct: 1584 AVTPSTYKGAP--SPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPAT---PAPKGTPT 1638
Query: 931 GPPPSPAAAPEAVPPPPAPPSYSDKGVQTPSKGTPA 966
PP +P++ ++ P + V SKG PA
Sbjct: 1639 SPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPA 1674
Score = 68.6 bits (166), Expect = 3e-11
Identities = 150/619 (24%), Positives = 199/619 (32%), Gaps = 115/619 (18%)
Query: 376 PGSKGEIYSPGA------GHPATKLPPDSLGSFQQQHTALQGPLASADLGLAPTPSPGLD 429
P KG +P A G PAT P + +L+G GLA P G
Sbjct: 1235 PSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKG-------GLATPPHKG-- 1285
Query: 430 RKALAEATNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILGPGEPGPQAPSRT 489
A N P + G ++ PP A P A P G PG P
Sbjct: 1286 ------APNPAVVTPPSPKGGPATSPPKG-------APTPPAATPPSPKGSPGTPPPKGA 1332
Query: 490 PSPRSPAPARVKAELSSP--TPGSSPVP----GELGLAGALFLPQYVFGPDAAPPASEIL 543
P+P + P K + P TP S P + G P + GP PP+
Sbjct: 1333 PTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSP--- 1389
Query: 544 AKMSELVHSRLQQGAGAGAGGAQTGLFPGAPK----GATCFECEITFSNVNNYYVHKRLY 599
K + S P P AT + ++T V + K
Sbjct: 1390 -KRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPA 1448
Query: 600 CSGRRAPEDAPAARRPKAPPGPARAPPGQPAEPDAPR-----SSPGPGAREEGAGGAATP 654
S AP+ PA K P P P EP AP+ SSP GA T
Sbjct: 1449 TS---APKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTL 1505
Query: 655 EDGAGGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPP 714
E +P S D P+ TL T + + P P
Sbjct: 1506 PAVIPSSPKEVPATPSSRRDPIA--PTATLLSK-----KTPATLAPKEALIPPAMTVPSP 1558
Query: 715 RR-PAAPPGPPGPAAPPAPSPAAPVRTRRRRKLYELHAAGAPPPPPPGHAPAPESPRPGS 773
++ PA P PA P + ++P Y+ GAP P PA SP
Sbjct: 1559 KKTPAIPTPKEAPATPSSKEASSPPAVTP--STYK----GAPSPKELLIPPAVTSP---- 1608
Query: 774 GSGSGPGLAPARSPGPAADGPIDLSKKPRRPLP-GAPAPALADYHECTACRVSFHSL-EA 831
+P +P P A P K P P P G P T+ V+ SL ++
Sbjct: 1609 --------SPKEAPTPPAVTPPSPEKGPATPAPKGTP----------TSPPVTPSSLKDS 1650
Query: 832 YLAHKKYSCP--AAPPPGALGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGPG 889
+ +C A P + GLPA P L L+ AP + P
Sbjct: 1651 PTSPASVTCKMGATVPQASKGLPAKKGPTA---------------LKEVLVAPAPESTPI 1695
Query: 890 VEARTPADRGP----SPAPAPAASPQP----GSRGPRDGLGPEPQEPPPGPPPSPAAAPE 941
+ A P +GP S A +P P P GS+GP + P P P A +
Sbjct: 1696 ITA--PTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKD 1753
Query: 942 AVPPPPAPPSYSDKGVQTP 960
A P P + + TP
Sbjct: 1754 ASHSPKGPLAPPESKASTP 1772
Score = 59.3 bits (142), Expect = 2e-08
Identities = 72/281 (25%), Positives = 97/281 (34%), Gaps = 36/281 (12%)
Query: 717 PAAPPGPPGPAAPPAPSPAAPVRTRRRRKLYELHAAGAPPPPPPGHAPAPESPRPGSGSG 776
P P P P+ PPA +P T++ + A AP P P +S + S
Sbjct: 728 PEIPKSVPSPSLPPAGTPPG---TKKVDGISHTSAL-APVASSPKECPTEDSGASATASS 783
Query: 777 SGPGLAPARSPGPAADGPIDLSKKP--RRPLPGAPAPALADYHECTACRVSFHSLEAYLA 834
G A SP P +K+P ++ G P + SF +
Sbjct: 784 KGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSF 843
Query: 835 HKKYSCPAA------PPPGALGLPAAACPY------CPPNGPVRGDLLEHFRLAHGLLLG 882
PA P P P+A P PP ++ G
Sbjct: 844 QGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATP 903
Query: 883 APLAGPGV--------EAR-TPADRGPSPAPAPAASPQPGSRGPRDGLGPEPQEPPPGPP 933
AP P + +AR TPA +G +P+P +P P + P P P+ P P
Sbjct: 904 APKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATP-----PSPKGGPATPS 958
Query: 934 PSPAAAPEAVPPPP---APPSYSDKGVQTPSKGTPAPLPNG 971
P A P A PP P + S KG TP TP P P G
Sbjct: 959 PKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATP-PSPKG 998
Score = 57.4 bits (137), Expect = 7e-08
Identities = 138/610 (22%), Positives = 199/610 (32%), Gaps = 95/610 (15%)
Query: 376 PGSKGEIYSPGAGH---PATKLPPDSLGSFQQQHTALQGPLASADLGLAPTPS--PGLDR 430
P SKG +P + P P G + +GP + G +P+ P +
Sbjct: 1354 PSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPK 1413
Query: 431 KALAEATNGEARAEPLAQNGGSSEPPAAPRSIK-VEAVEEPEAAPILGPGEPGPQAPSRT 489
KA A E A P G + P P S+K A P+ P + P P+ T
Sbjct: 1414 KAPATPVTREGAATP--SKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVT 1471
Query: 490 P-SPRSP-APARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGPDAAPPAS-----EI 542
P SP+ P AP +V S ++P P GA LP + PA+ +
Sbjct: 1472 PPSPKEPPAPKQVATSSSPKKAPATPAP-----MGAPTLPAVIPSSPKEVPATPSSRRDP 1526
Query: 543 LAKMSELVHSRLQQGAGAGAGGAQTGLFPGAPKGATCFECEITFSNVNNYYVHKRLYCSG 602
+A + L+ + + +PK
Sbjct: 1527 IAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIP--------------------- 1565
Query: 603 RRAPEDAPAARRPKAPPGPARAPPG------QPAEPDAPRSSPGPGAREEGAGGAATP-- 654
P++APA K P P P E P + P +E A TP
Sbjct: 1566 --TPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPS 1623
Query: 655 -EDGAGGRGSEGSQ-SPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDP 712
E G +G+ SP + +D P+ C + + + AS+ P
Sbjct: 1624 PEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQ----------ASKGLP 1673
Query: 713 PPRRPAAPPGP-PGPAAPPAPSPAAPVRTRRRRKLYELHAAGAPPPPPPGHAPAPESPRP 771
+ P A PA P AP R + K ++ PP P + S P
Sbjct: 1674 AKKGPTALKEVLVAPAPESTPIITAPTRKGPQTK----KSSATSPPICPDPSAKNGSKGP 1729
Query: 772 GSGSGSGPGLAPARSPGPAADGPIDLSKKPRRPLPGAPAPALADYHECTACRVSFHSLEA 831
S P L + A G D S P+ PL AP + A A + E
Sbjct: 1730 LSTVAPAPLLPVQKDSSKTAKGK-DASHSPKGPL--APPESKASTPLTAA------AFEK 1780
Query: 832 YLAHKKYSCPAAPPPGALGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGPGVE 891
L + + +A P + LP A P P P + L + GL+L +P +
Sbjct: 1781 VLPKPESASVSAAPSPPVSLPLAPSPV--PTLPPKQQFLPS---SPGLVLESPS-----K 1830
Query: 892 ARTPADRGPSPAPAPAASPQPGSRGPRDGLGPEPQEPPPGPPPSPAAAPEAVPPPPAPPS 951
PAD P P+P S G P P P A P P P +
Sbjct: 1831 PLAPADEDEL---LPLIPPEPISGGV-----PFQSVLVNMPTPKSAGIPVPTPSAKQPVT 1882
Query: 952 YSDKGVQTPS 961
++KG T S
Sbjct: 1883 KNNKGSGTES 1892
Score = 33.1 bits (74), Expect = 1.3
Identities = 31/110 (28%), Positives = 40/110 (36%), Gaps = 19/110 (17%)
Query: 42 APSPPSADVNSPP-----------PLPPPTSPGGPKELEGQEPEPR----PTEEEPGSPW 86
AP+PP+A SP P PP +P PK P P+ P P SP
Sbjct: 985 APTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSP- 1043
Query: 87 SGPDELEPVVQDGQRRIRARLSLATGLSWGPFHGSVQTRASSPRQAEPSP 136
G P+ + A L G GP S++ + P PSP
Sbjct: 1044 KGSPAATPLPKGAPTTPAATLPSPKG---GPATPSLKGAPTPPAATPPSP 1090
Score = 33.1 bits (74), Expect = 1.3
Identities = 20/53 (37%), Positives = 21/53 (39%), Gaps = 6/53 (11%)
Query: 43 PSPPSADVNSPP---PLPPPTSPGGPKELEGQEP---EPRPTEEEPGSPWSGP 89
PSP SPP P PP +P PK G P P P P SP P
Sbjct: 1295 PSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTP 1347
Score = 32.7 bits (73), Expect = 1.8
Identities = 23/63 (36%), Positives = 29/63 (46%), Gaps = 11/63 (17%)
Query: 38 TAPEAPSPPSA-DVNSPPPLPPPTSPG--GPKEL--------EGQEPEPRPTEEEPGSPW 86
T EAP+ PS+ + +SPP + P T G PKEL + P P P SP
Sbjct: 1566 TPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPE 1625
Query: 87 SGP 89
GP
Sbjct: 1626 KGP 1628
Score = 32.3 bits (72), Expect = 2.3
Identities = 55/199 (27%), Positives = 73/199 (36%), Gaps = 40/199 (20%)
Query: 722 GPPGPAAPPAPSPAAPVRTRRRRKLYELHAA--GAPPPPPPGHAPAP-ESPRPGSGSGSG 778
G PGP PP SPA + L AA +P P P A P E P P S SG+
Sbjct: 39 GQPGPTLPPPCSPAP--------QQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTA 90
Query: 779 PGLAPARSPGPAADGPIDLSKKPRRPLPGA----PAPALADYHECTACRVSFHSLEAYLA 834
L G A + P L P+ A +P +A + T + +L A
Sbjct: 91 LPL------GTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAP 144
Query: 835 HKKYSCPAAPPPGALGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGPGVEART 894
H A PP P+ A +G V + L AP+A E +T
Sbjct: 145 HSVQKSSAFPPNLLTSPPSVA---VAESGSV-------------ITLSAPIAPS--EPKT 186
Query: 895 PADRGPSP-APAPAASPQP 912
++ PS P P +P P
Sbjct: 187 NLNKVPSEVVPNPKGTPSP 205
Score = 32.0 bits (71), Expect = 3.0
Identities = 23/77 (29%), Positives = 30/77 (38%), Gaps = 8/77 (10%)
Query: 900 PSPAPAPAASPQPGSRGPRDGLG-PEPQEPPP---GPPPSPAAAPEAVPPPPAPPSYSDK 955
P P A P + LG P P PPP P P +A P P+P + +
Sbjct: 17 PQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIAST 76
Query: 956 GVQTP----SKGTPAPL 968
++ P S GT PL
Sbjct: 77 PLEVPFPQSSSGTALPL 93
Score = 32.0 bits (71), Expect = 3.0
Identities = 21/67 (31%), Positives = 24/67 (35%), Gaps = 14/67 (20%)
Query: 42 APSPPSADVNSP--------------PPLPPPTSPGGPKELEGQEPEPRPTEEEPGSPWS 87
AP+PP+A SP PP P SP G + P P P SP
Sbjct: 939 APTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKG 998
Query: 88 GPDELEP 94
GP P
Sbjct: 999 GPATPSP 1005
Score = 31.6 bits (70), Expect = 3.9
Identities = 19/55 (34%), Positives = 21/55 (38%), Gaps = 3/55 (5%)
Query: 40 PEAPSPPSADVNSPPPLPPPTSPGGPKELEGQEPEPRPTEEEPGSPWSGPDELEP 94
P +PSP A PP P SP G + P P P SP GP P
Sbjct: 931 PASPSPKGAPT---PPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSP 982
Score = 31.6 bits (70), Expect = 3.9
Identities = 53/201 (26%), Positives = 71/201 (35%), Gaps = 22/201 (10%)
Query: 37 ATAPE--APSPPSADVNSP---PPLPPPTSPGGPKELEGQEPEPRPTEEEPG-SPWSGPD 90
AT+P AP+PP+A SP P PPP G P P P+ T P +P S
Sbjct: 1302 ATSPPKGAPTPPAATPPSPKGSPGTPPP--KGAPTPPAVTPPSPKGTPTLPATTPSSKGG 1359
Query: 91 ELEPVVQDGQRRIRARLSLATGLSWGPFHGSVQTRASSPRQAEPSPALTLLLVDEACWLR 150
P ++G A S G + P SP+ SPA+ L +A
Sbjct: 1360 PTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKA---- 1415
Query: 151 TLPQALTEAEANTEIHRKDDALWCRVTKP-VPAGGLLSVLLTAEPHSTPGHPVKK-EPAE 208
P E + D +T P V L T+ P P P K +P
Sbjct: 1416 --PATPVTREGAATPSKGD------LTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTL 1467
Query: 209 PTCPAPAHDLQLLPQQAGMAS 229
P P+ P+Q +S
Sbjct: 1468 PAVTPPSPKEPPAPKQVATSS 1488
Score = 30.4 bits (67), Expect = 8.7
Identities = 38/122 (31%), Positives = 50/122 (40%), Gaps = 25/122 (20%)
Query: 30 ASHMEQKATAPEAPSPPS---ADVNSPPPLPPPTSP--------GGP--KELEGQEPEPR 76
A+ + A+ P A +PPS + +P P PT+P GGP L+G P
Sbjct: 1025 ATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKG---APT 1081
Query: 77 PTEEEPGSPWSGPDELEPVVQDGQRRIRARL--SLATGLSWGPFHGSVQTRASSPRQAEP 134
P P SP GP P G A S GL+ P G+ T A++P P
Sbjct: 1082 PPAATPPSPKGGPATPSP---KGAPMPPAATPPSPKGGLATPPHKGAPTTPAATP----P 1134
Query: 135 SP 136
SP
Sbjct: 1135 SP 1136
Score = 30.4 bits (67), Expect = 8.7
Identities = 22/65 (33%), Positives = 25/65 (38%), Gaps = 8/65 (12%)
Query: 38 TAPEAPSP-PSADVNSPPPLPPPTSPGG-PKELEG------QEPEPRPTEEEPGSPWSGP 89
T P A P P +PPP PT P P L+G + P P P SP GP
Sbjct: 1242 TTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGP 1301
Query: 90 DELEP 94
P
Sbjct: 1302 ATSPP 1306
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 100 bits (249), Expect = 7e-21
Identities = 150/590 (25%), Positives = 197/590 (33%), Gaps = 122/590 (20%)
Query: 421 APTPSPGLDRKALAE-ATNGEARAEPLAQN----GGSSEPPAAPRSIKVEAVEEPEAAPI 475
+P P P + AL G +PLA+ GG++ P +APR+ P +
Sbjct: 32 SPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRPPAS--- 88
Query: 476 LGPGEPGPQAPSRTPSPRSPAPARVKAELSSPTPGSSPV-PGELGLAGALFLPQYVFGPD 534
G GE P A + +P P +SSP S PG LG G
Sbjct: 89 -GRGERAPPAKNTSPGP-----------VSSPGRASGTTRPGPLGQKGLRI--------- 127
Query: 535 AAPPASEILAKMSELVHSRLQQGAGAGAGGAQTGLFPGAPKGATCFECEITFSNVNNYYV 594
A E +A+ + + + AGA +G PG P A + V
Sbjct: 128 ---SAEETVAR-GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVG---- 179
Query: 595 HKRLYCSGRRAPEDAPAARRPKAPPGPARAPPGQPAEPDAPRSSPGPGAREEGAGGAATP 654
P AP+AR P+ P R +E SP R GG P
Sbjct: 180 ----------LPRPAPSAR-PRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRP 228
Query: 655 EDGAGGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHD-PP 713
+ + SP S A P R H + K P
Sbjct: 229 ASRSLSSSATPLSSPARSGPSARGTP----------RAPAHPSQPKPKGLQALRPPQVTP 278
Query: 714 PRRPAAPP-GP--------PGPAAPPAPSPAAPVRTRRRRKLYELHAAGAPPPPPPGHAP 764
PR+ AAP GP P P+APP+PS ++T +PP PP A
Sbjct: 279 PRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQT-----------LPSPPATPPSQAT 327
Query: 765 APESPRPGSGSGS---GPGLAPARSPGPAADGPIDLSKKPRRPLPGAPAPA--LADYHEC 819
+ S P L+P +P P A + L P P A P LA
Sbjct: 328 TSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQ 387
Query: 820 TACRVSFHSLEAYLAHKKYSCPAAPPPGALGLPAAACPYCPPNGPVRGDLLEHFRLAHGL 879
++ H L+A P +PPP P P+ PP P A
Sbjct: 388 APNALAVHLLQA---------PFSPPPS----PPVQAPFSPPASPPVSPSATPPSQAPPS 434
Query: 880 LLGAPLAGPGVEARTPADRGPSPAPAPAASPQPGSRGPRDGLGPEPQEPP---------- 929
L PL P +P PS P P A P P + P P PQ PP
Sbjct: 435 LAAPPLQVPPSPPASPP-MSPSATPPPQAPP-PLAAPPLQLAKPPPQAPPALATPPLQAL 492
Query: 930 PGPPPS--------PAAA----PEAVPPPPAPPSYSDKGVQTPSKGTPAP 967
P PP S P+A+ P A PPP APP + +Q P +P
Sbjct: 493 PSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASP 542
Score = 74.7 bits (182), Expect = 4e-13
Identities = 153/594 (25%), Positives = 198/594 (33%), Gaps = 130/594 (21%)
Query: 390 PATKLPPDSLGSFQQQHTALQGPLA----SADLGLAPTPSPGLDRKAL---AEATNG-EA 441
P T+ P S+ S + T P A SA GL S L A + A +G A
Sbjct: 191 PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSA 250
Query: 442 RAEPLAQNGGSSEPPAAPRSIKVEAVEEP--EAAPILGPGEPGPQAPSRTPSPRSP---- 495
R P A S P ++++ V P +AAP LGP P A TPSP +P
Sbjct: 251 RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLA---TPSPSAPPSPS 307
Query: 496 APARVKAELSSPTPGSSPVPGELGL----AGALFLPQYVFGPDAAPPASEILAKMSELVH 551
AP ++ S P S LG A FLP P A PP A L
Sbjct: 308 APPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPA----LAL 363
Query: 552 SRLQQGAGAGAGGAQTGLF---PGAPKGATCFECEITFSNVNNYYVHKRLYCSGRRAPED 608
LQ A + L P AP + FS + V S +P
Sbjct: 364 PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF--SPPASPPV 421
Query: 609 APAARRPKAPPGPARAPPGQ--PAEPDAPRSSPGPGAREEGAGGAATPEDGAGGRGSEGS 666
+P+A P P APP Q P+ P +P SP + A P + +
Sbjct: 422 SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP-------LQLA 474
Query: 667 QSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRPAAPPGPPGP 726
+ P + P + L P PA+ PG P
Sbjct: 475 KPPPQAPPALATPPLQAL-----------------------------PSPPASFPGQ-AP 504
Query: 727 AAPPAPSPAAPVRTRRRRKLYELHAAGAPPPPPPGHAPAPESPRPGSGSGSGPGLAPARS 786
+P A P +P+ T PPP P AP P S S AP R
Sbjct: 505 FSPSASLPMSPLAT--------------PPPQAPPVLAAPLLQVPPSPPASPTLQAPRRP 550
Query: 787 PGPAAD----GP-IDLSKKPRRPLPGAPAPA-------LADYHECTACRVSFHSLEAYLA 834
P P D GP + L+ P P P + +P+ LA H +A L Y +
Sbjct: 551 PTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAG-HSSSATSTP-EELRGYDS 608
Query: 835 HKKYSCPAAPPPGA--------------------LGLPAAACPYCPPNGPVRGDLLEHFR 874
+ A+PPP A G P A P+ P GP D
Sbjct: 609 GPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSAD------ 662
Query: 875 LAHGLLLGAPLAGPGVEARTPADRGPSPAPAPAASPQPGSRGPRDGLGPEPQEP 928
GL GP E+ TPA P P+P S + G G G + P
Sbjct: 663 ---GLCTIYETEGP--ESATPAPGALDPGPSPGTSGGKAAAGA--GAGASSRSP 709
Score = 72.4 bits (176), Expect = 2e-12
Identities = 122/459 (26%), Positives = 144/459 (31%), Gaps = 111/459 (24%)
Query: 610 PAARRP----KAPPGPARAPPGQPAEPDAPRSSPGPGA--------REEGAGGAATPEDG 657
PAAR P PPG R PP P P A R GA R G GGA PE
Sbjct: 17 PAARAPGLLTPRPPGSPRPPP--PVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESA 74
Query: 658 ------------AGGRGSEG------SQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYT 699
A GRG S P SS A +R S ET
Sbjct: 75 PRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVA 134
Query: 700 VHKRYYCASRHDPPPRRPAAPPGPPGPAAPPAPSPAAPVRTRRRRK------LYELHAAG 753
K P+R A G + P P +P RR R L +
Sbjct: 135 RGKA-------TEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSA 187
Query: 754 APPPPPPG----------HAPAPESP----RPGSGSG------------SGPGLAPARSP 787
P PP G H+ SP RP +G G + P +PARS
Sbjct: 188 RPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARS- 246
Query: 788 GPAADGPIDLSKKPRRPLPG---APAPALADYHECTACRVSFHSLEAYLAHKKYSCPAAP 844
GP+A G P +P P A P A + LA S P +P
Sbjct: 247 GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSP 306
Query: 845 --PPGALGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLA--------GPGVEART 894
PP LP+ P PP+ + H L PL+ P A
Sbjct: 307 SAPPSLQTLPSP--PATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALP 364
Query: 895 PADRGPSPAPAPAASP--QPGSRGP--------RDGLGPEPQ-------EPPPGPPPSPA 937
P PSP +P SP P + P + P P PP PP SP+
Sbjct: 365 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 424
Query: 938 AAPE-------AVPPPPAPPSYSDKGVQTPSKGTPAPLP 969
A P A PP PPS +PS P P
Sbjct: 425 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP 463
Score = 45.4 bits (106), Expect = 3e-04
Identities = 75/299 (25%), Positives = 97/299 (32%), Gaps = 53/299 (17%)
Query: 384 SPGAGHPATKLPPDSLGSFQQQHTALQGPLASADLGLAPTPSPGLDRKALAE-ATNGEAR 442
SP A P PP + Q Q P A A L PSP A + +
Sbjct: 453 SPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLP 512
Query: 443 AEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILGPGEPGPQAPSRTPSPRSPAPARVKA 502
PLA + PP AP + ++ P + P P QAP R P+P
Sbjct: 513 MSPLA-----TPPPQAPPVLAAPLLQVPPSP----PASPTLQAPRRPPTPGPDTSVSGPR 563
Query: 503 ELSSPTPGSSPVPGELGLAGALFLPQYVFGPDAAPPASEILAKMSELVHSRLQQGAGAGA 562
+ PG P P + GPD A +S + EL +G +G
Sbjct: 564 LTLALAPGPPPPPSRSP-------SSTLSGPDLAGHSSSATSTPEEL------RGYDSGP 610
Query: 563 GGAQTGLFPGAPKGATCFECEITFSNVNNYYVHKRLYCSGRRAPEDAPAARRPKAP-PGP 621
G P + A C H + G P A P AP P P
Sbjct: 611 EGGAAASPPPDAELAAC---------------HPAAWSRGPAPPLAFRGA--PGAPLPWP 653
Query: 622 ARAPPGQP------AEPDAPRS-SPGPGAREEG-----AGGAATPEDGAGGRGSEGSQS 668
PG E + P S +P PGA + G +GG A GAG Q+
Sbjct: 654 PATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQA 712
Score = 37.0 bits (84), Expect = 0.093
Identities = 61/249 (24%), Positives = 77/249 (30%), Gaps = 29/249 (11%)
Query: 752 AGAPPPPPPGHAPAPESPRPGSGSGSGPGLAPARSPGPAADGPIDLSKKPRRPLPGAPAP 811
AGA P AP +PRP P + PA A G + +KP G
Sbjct: 10 AGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAV--GRKPLAERAGGIGG 67
Query: 812 ALADYHECTACRVSFHSLEAYLAHKKYSCPAAPPPGALGLPAAACPYCPPNGPVRGDLLE 871
A A A ++ PG + P A P GP+ L
Sbjct: 68 ATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP-GPLGQKGLR 126
Query: 872 ---HFRLAHGLLLGAP-----LAGPGVEARTPADRGPSPA----------------PAPA 907
+A G AP AG + P PSPA PAP+
Sbjct: 127 ISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPS 186
Query: 908 ASPQPGSRGPRDGLGPEPQEPPPGPPPSPAAAPEAVPPPPAPPSYSDKGVQTP--SKGTP 965
A P+P + GPR + + P P+ P A P S S TP S
Sbjct: 187 ARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARS 246
Query: 966 APLPNGNHR 974
P G R
Sbjct: 247 GPSARGTPR 255
Score = 36.6 bits (83), Expect = 0.12
Identities = 45/171 (26%), Positives = 54/171 (31%), Gaps = 25/171 (14%)
Query: 40 PEAPSPPSADVNSPPPLP-PPTSPGGPKELEGQEP-EPRPTEEEPGSPWSGPDELEPVVQ 97
P P+ P+ PP P P TS GP+ P P P P S SGPD +
Sbjct: 536 PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPD-----LA 590
Query: 98 DGQRRIRARLSLATGLSWGPFHGSVQTRASSPRQAEPSPALTLLLVDEACWLR--TLPQA 155
+ G GP G+ A P P L A W R P A
Sbjct: 591 GHSSSATSTPEELRGYDSGPEGGAA---------ASPPPDAELAACHPAAWSRGPAPPLA 641
Query: 156 LTEAEANTEIHRKDDALWCRVTKPVPAGGLLSVLLTAEPHSTPGHPVKKEP 206
A W T P A GL ++ T P S P +P
Sbjct: 642 FRGAPG-------APLPWPPATGPGSADGLCTIYETEGPESATPAPGALDP 685
Score = 35.8 bits (81), Expect = 0.21
Identities = 47/181 (25%), Positives = 59/181 (32%), Gaps = 29/181 (16%)
Query: 39 APEAPSPPSADVNSP--PPLPPPTSPGGPKELEGQEPEPRPTEEEPGSPWSGP---DELE 93
AP +P PPS V +P PP PP SP + P + P SP + P
Sbjct: 399 APFSP-PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSAT 457
Query: 94 PVVQDGQRRIRARLSLATGLSWGPFHGSVQTRASSPRQAEPSPALTLLLVDEACWLRTLP 153
P Q L LA P A+ P QA PSP + +LP
Sbjct: 458 PPPQAPPPLAAPPLQLAKPPPQAP-----PALATPPLQALPSPPASFPGQAPFSPSASLP 512
Query: 154 QALTEAEANTEIHRKDDALWCRVTKPVPAGGLLSVLLTAEPHSTPGHPVKKEPAEPTCPA 213
+ T P A +L+ L P S P P + P P P
Sbjct: 513 MSPL------------------ATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPG 554
Query: 214 P 214
P
Sbjct: 555 P 555
Score = 35.8 bits (81), Expect = 0.21
Identities = 55/212 (25%), Positives = 77/212 (36%), Gaps = 38/212 (17%)
Query: 384 SPGAGHPATKLP------PDSLG---SFQQQHTALQGPLASADLGLAPTPSPGLDRKALA 434
+PG P ++ P PD G S L+G + + G A +P P + A
Sbjct: 569 APGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACH 628
Query: 435 EATNGEARAEPLAQNGG---------SSEPPAAPRSIKVEAVEEPEAA-PILGPGEPGPQ 484
A A PLA G ++ P +A + E PE+A P G +PGP
Sbjct: 629 PAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGP- 687
Query: 485 APSRTPSPRSPAPARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGPDAAPPASEILA 544
SP + KA + SS P + L G L P A AS +
Sbjct: 688 ---------SPGTSGGKAAAGAGAGASSRSPKQARL-GEL--------PLGALQASVVQH 729
Query: 545 KMSELVHSRLQQGAGAGAGGAQTGLFPGAPKG 576
+S + +GA G+GG G G G
Sbjct: 730 LLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTG 761
Score = 31.6 bits (70), Expect = 3.9
Identities = 31/108 (28%), Positives = 39/108 (36%), Gaps = 21/108 (19%)
Query: 36 KATAPEAPSPPSADVNSPPPLPPPTSPGGPKELEGQEPEPRPTEEEPGSPWSGPDELEPV 95
+AT PSPP + + +PPP PP L + P P P SP + P P
Sbjct: 336 QATHSFLPSPPLSPLATPPPQAPPA-----LALPPLQAPPSPPASPPLSPLATPSPQAP- 389
Query: 96 VQDGQRRIRARLSLATGLSWGPF----HGSVQTRASSPRQAEPSPALT 139
+LA L PF VQ S P SP+ T
Sbjct: 390 -----------NALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSAT 426
>gi|148276998 zinc finger protein 628 [Homo sapiens]
Length = 1055
Score = 100 bits (249), Expect = 7e-21
Identities = 126/512 (24%), Positives = 182/512 (35%), Gaps = 89/512 (17%)
Query: 199 GHPVKKEPAEPTCPAPAHDLQLLPQQAGMASILATAVINKDVFPCKDCGIWYRSERNLQA 258
GH ++ P CP LL + + L F C CG+ ++ + Q
Sbjct: 81 GHTGERPYQCPDCPKAFKRSSLLQIHRSVHTGLRA-------FICGQCGLAFKWSSHYQY 133
Query: 259 HLLYYCASRQGTGSPAAAATDEKPKETYPNERVCPFPQCRKSCPSASSLEIHMRSHSGER 318
HL RQ TG ER P P C K+ ++SSL H H+GER
Sbjct: 134 HL------RQHTG-----------------ERPYPCPDCPKAFKNSSSLRRHRHVHTGER 170
Query: 319 PFVCLICLSAFTTKANCERHLKVHTDTLSGVCHSCGFISTTRDILYSHLVTNHMVCQPGS 378
P+ C +C +FT N +H +VHT C C T L H T+ PG+
Sbjct: 171 PYTCGVCGKSFTQSTNLRQHQRVHTGERPFRCPLCPKTFTHSSNLLLHQRTHGAAPAPGT 230
Query: 379 KGEIYSPGAGHPATKLPPDSLGSFQQQHTALQGPLASADLGLAPTPSPGLDRKALAEATN 438
P + P D ++ Q+H LQ A P P P + LA A
Sbjct: 231 ASAAPPPQSREPGKVFVCD---AYLQRH--LQPHSPPAPPAPPPPPPPVVPELFLAAA-- 283
Query: 439 GEARAEPLAQNGGSSEPPAAPR-SIKVEAVEEPEAAPILGPGEPGPQAPSRTPSPRSPAP 497
E E + + G + ++ ++ + P+AAP P E +AP + P SP P
Sbjct: 284 -ETTVELVYRCDGCEQGFSSEELLLEHQPCPGPDAAP--QPQEAPAEAP-KADQPPSPLP 339
Query: 498 ARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGPDAAPPASEILAKMSELVHSRLQQG 557
P P ++P PG A P + ++ L SR Q
Sbjct: 340 -------QPPPPAAAPAPG-----------------FACLPCGKSFRTVAGL--SRHQHS 373
Query: 558 AGAGAGGAQTGLFPGAPKGATCFECEITFSNVNNYYVHKRLYCSGRRAPEDAPAARRPKA 617
GA G A C C+ +F + + H++ + E+A A R P
Sbjct: 374 HGAAGGQA-----------FRCGSCDGSFPQLASLLAHQQCHV------EEAAAGRPPPQ 416
Query: 618 PPGPARAPPGQPAEPDAPRSSPGPGAREEGAGGAATPEDGAGGRGSEGSQSPGSSVDDAE 677
P +P P AP P P A E G +GS G + D
Sbjct: 417 AEAAEVTCPQEPLAPAAPVPPPPPSAPASAERPYKCAECGKSFKGSSGLRY--HLRDHTG 474
Query: 678 DDPSRTLCEACNIRFSRHETYTVHKRYYCASR 709
+ P + C C F R +H+R + R
Sbjct: 475 ERPYQ--CGECGKAFKRSSLLAIHQRVHTGLR 504
Score = 82.0 bits (201), Expect = 3e-15
Identities = 113/474 (23%), Positives = 159/474 (33%), Gaps = 78/474 (16%)
Query: 283 KETYPNERVCPFPQCRKSCPSASSLEIHMRSHSGERPFVCLICLSAFTTKANCERHLKVH 342
+ T+ ER P C K+ +S+L H R H+GERP+ C C AF + + H VH
Sbjct: 51 QRTHTGERPYKCPDCPKAFKGSSALLYHQRGHTGERPYQCPDCPKAFKRSSLLQIHRSVH 110
Query: 343 TDTLSGVCHSCGFISTTRDILYSHLVTNHMVCQPGSKGEIYSPGAGHPATKLPPDSLGSF 402
T + +C CG HL + GE P P SL
Sbjct: 111 TGLRAFICGQCGLAFKWSSHYQYHLRQH--------TGERPYPCPDCPKAFKNSSSLRRH 162
Query: 403 QQQHTALQGPLASADLGLAPTPSPGLDRKALAEATNGEARAEPLAQNGGSSEPPAAPRSI 462
+ HT + P G + T S L + R PL P S
Sbjct: 163 RHVHTG-ERPYTCGVCGKSFTQSTNLRQHQRVHTGERPFRC-PLC-------PKTFTHSS 213
Query: 463 KVEAVEEPE-AAPILGPGEPGPQAPSRTPSPRSPAPARVKAELSSPTPGSSPVPGELGLA 521
+ + AAP G P SR P A ++ L +P + P P
Sbjct: 214 NLLLHQRTHGAAPAPGTASAAPPPQSREPGKVFVCDAYLQRHLQPHSPPAPPAP------ 267
Query: 522 GALFLPQYVFGPDAAPPASEILAKMSELVHSRLQQGAGAGAGGAQTGLFPGAPKGATCFE 581
P P E+ +E + + C
Sbjct: 268 ----------PPPPPPVVPELFLAAAETTVELVYR----------------------CDG 295
Query: 582 CEITFSNVNNYYVHKRLYCSGRRAPEDAPAARRPKAPPGPARAPPGQPAEPDAPRSSPGP 641
CE FS+ H+ C G P+ AP + A A PP +P P ++P P
Sbjct: 296 CEQGFSSEELLLEHQP--CPG---PDAAPQPQEAPAEAPKADQPPSPLPQPPPPAAAPAP 350
Query: 642 GAREEGAGGAATPEDGAGGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVH 701
G G + G S S G++ A C +C+ F + + H
Sbjct: 351 GFACLPCGKSFRTVAGL----SRHQHSHGAAGGQA------FRCGSCDGSFPQLASLLAH 400
Query: 702 KRYYC--ASRHDPPPRRPAA----PPGPPGPAAP-PAPSPAAPVRTRRRRKLYE 748
++ + A+ PPP+ AA P P PAAP P P P+AP R K E
Sbjct: 401 QQCHVEEAAAGRPPPQAEAAEVTCPQEPLAPAAPVPPPPPSAPASAERPYKCAE 454
Score = 73.2 bits (178), Expect = 1e-12
Identities = 144/593 (24%), Positives = 196/593 (33%), Gaps = 119/593 (20%)
Query: 241 FPCKDCGIWYRSERNLQAHLLYYCASRQ---GTGSPAAAATD--EKPKETYPNERVCPFP 295
F C CG+ ++ + Q HL + R G A T + + + ER
Sbjct: 506 FTCGQCGLTFKWSSHYQYHLRLHSGERPYACGECGKAFRNTSCLRRHRHVHTGERPHACG 565
Query: 296 QCRKSCPSASSLEIHMRSHSGERPFVCLICLSAFTTKANCERHLKVHTDTLSGVCHSCGF 355
C KS S+L H R H+GERPF C +C FT +N H + H+ C CG
Sbjct: 566 VCGKSFAQTSNLRQHQRVHTGERPFRCPLCPKTFTHSSNLLLHQRTHSAERPFTCPICGR 625
Query: 356 ISTTRDILYSHLVTNHMVCQPGSKGEIYSPGAGHPATKLPPDSLGSFQQQHTALQGPLAS 415
L HL T+ P S +P AG PP L A + P A+
Sbjct: 626 GFVMAAYLQRHLRTHAPANTPPS---TTAPAAG----PQPPAPL-------AAARAPPAT 671
Query: 416 ADLGLAPTPSPGLDRKALAEATNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPI 475
D+ + P L E G A+A L PAAP S V+ + +
Sbjct: 672 QDVHVL----PHLQATLSLEVAGGTAQAPSLG--------PAAPNSQTFLLVQTAQGLQL 719
Query: 476 LGPGEPGPQAPSRTPSPRSPAPARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGPDA 535
+ PS P PTP P P P+ + P +
Sbjct: 720 I-------------PSSVQP-----------PTPPPPPAP-----------PKLILLPSS 744
Query: 536 APPASEILAKMSELVHSRLQQGAGA----GAGGAQTGLFPGAPKGAT-CFECEITFSNVN 590
+ A A+ + QGAG G GG G+ A GA+ + I NV
Sbjct: 745 SAGAGGGRARQGPRAVGKAGQGAGVVWLPGPGG--LGVQGAASAGASGTGQSLIVLQNVG 802
Query: 591 NYYVHKRLYCSG------RRAPEDAPAARRPKAPPGPARAPPG--------QPA-EPDAP 635
+ SG R APE +P + P QPA E
Sbjct: 803 GGEAGPQ-EMSGVQLQPLRPAPEVTTVQLQPAQEVTTVQLQPAQEVTTVQLQPAQEVTTV 861
Query: 636 RSSPGPGAREEGAGGAATPEDG-----AGGRGSEGSQSPGSSVDDAEDDPSRTLCEACNI 690
+ P G +GGA E G E PG +A D + T ++
Sbjct: 862 QLQPVAGQLSNSSGGAVATEAPNLLVVQSGAAEELLTGPGPG--EAGDGEAST-GVVQDV 918
Query: 691 RFSRHETYTVHKRYYCASRHDPPPRR---PAAPPGPPGPAAPPAPSPAAP----VRTRRR 743
F +T + S D R PPG PPA P +R+
Sbjct: 919 LFETLQTDEGLQSVLVLSGADGEQTRLCVQEVETLPPGLTEPPATGPPGQKLLIIRSAPA 978
Query: 744 RKLYELHAAG---------APPPPPPGHAPAPESPRPGS------GSGSGPGL 781
+L + G APPP P PA P S +G+GPG+
Sbjct: 979 TELLDSSNTGGGTATLQLLAPPPSGPASGPAGLPGAPASQMVQVVPAGAGPGV 1031
Score = 70.9 bits (172), Expect = 6e-12
Identities = 104/420 (24%), Positives = 148/420 (35%), Gaps = 79/420 (18%)
Query: 272 SPAAAATDEKPKETYPNERVCPFPQCRKSCPSASSLEIHMRSHSGERPFVCLICLSAFTT 331
+PAA P ER +C KS +S L H+R H+GERP+ C C AF
Sbjct: 430 APAAPVPPPPPSAPASAERPYKCAECGKSFKGSSGLRYHLRDHTGERPYQCGECGKAFKR 489
Query: 332 KANCERHLKVHTDTLSGVCHSCGFISTTRDILYSHLVTNHMVCQPGSKGEIYSPGAGHPA 391
+ H +VHT + C CG ++ Y + + H +P + GE G
Sbjct: 490 SSLLAIHQRVHTGLRAFTCGQCG-LTFKWSSHYQYHLRLHSGERPYACGEC---GKAFRN 545
Query: 392 TKLPPDSLGSFQQQHTALQGPLASADLGLAPTPSPGLDRKALAEATNGEARAEPLAQNGG 451
T L + HT + P A G+ K+ A+ +N R G
Sbjct: 546 T----SCLRRHRHVHTG-ERPHAC-----------GVCGKSFAQTSN--LRQHQRVHTGE 587
Query: 452 SS-EPPAAPRSI----------KVEAVEEPEAAPILGPGEPGPQAPSRTPSPRSPAPARV 500
P P++ + + E P PI G G A R+ APA
Sbjct: 588 RPFRCPLCPKTFTHSSNLLLHQRTHSAERPFTCPICGRG--FVMAAYLQRHLRTHAPANT 645
Query: 501 KAELSSPTPGSSPVPGELGLAGALFLPQYVFGPDAAPPASEILAKMSELVHSRLQQGAGA 560
++P G P P L A APPA++ + + L + + AG
Sbjct: 646 PPSTTAPAAGPQP-PAPLAAA-------------RAPPATQDVHVLPHLQATLSLEVAGG 691
Query: 561 GAGGAQTGLFPGAPKGATCFECEITFSNVNNYYVHKRLYCSGRRAPEDAPAARRPKAPPG 620
A G P AP T L + + P++ +P PP
Sbjct: 692 TAQAPSLG--PAAPNSQTF------------------LLVQTAQGLQLIPSSVQPPTPPP 731
Query: 621 PARAP-----PGQPAEPDAPRSSPGP---GAREEGAGGAATPEDGAGGRGSEGSQSPGSS 672
P P P A R+ GP G +GAG P G GG G +G+ S G+S
Sbjct: 732 PPAPPKLILLPSSSAGAGGGRARQGPRAVGKAGQGAGVVWLP--GPGGLGVQGAASAGAS 789
Score = 56.2 bits (134), Expect = 1e-07
Identities = 74/285 (25%), Positives = 93/285 (32%), Gaps = 70/285 (24%)
Query: 685 CEACNIRFSRHETYTVHKRYYCASRHDPPPRRPAAPPGPPGPAAPPAPSPAAPVRTRRRR 744
C C F+ +H+R H P A PP + P +R
Sbjct: 202 CPLCPKTFTHSSNLLLHQR-----THGAAPAPGTASAAPPPQSREPGKVFVCDAYLQRHL 256
Query: 745 KLYELHAAGAPPPPPPGHAP------------------------------APESPRPGSG 774
+ + A APPPPPP P P PG
Sbjct: 257 QPHSPPAPPAPPPPPPPVVPELFLAAAETTVELVYRCDGCEQGFSSEELLLEHQPCPGPD 316
Query: 775 SGSGPGLAPARSPGPAADGPIDLSKKPRRPLPGAPAPALADYHECTACRVSFHSLEAYLA 834
+ P APA +P A P L + P P APAP A C C SF ++
Sbjct: 317 AAPQPQEAPAEAP-KADQPPSPLPQPP--PPAAAPAPGFA----CLPCGKSFRTVAGLSR 369
Query: 835 HKKYSCPAAPPPGALGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGPGVEART 894
H+ GA G A C C + P LL H + H VE
Sbjct: 370 HQH-------SHGAAGGQAFRCGSCDGSFPQLASLLAH-QQCH------------VE--- 406
Query: 895 PADRGPSPAPAPAASPQPGSRGPRDGLGPEPQEPPPGPPPSPAAA 939
A G P A AA P++ L P PPP PP +PA+A
Sbjct: 407 EAAAGRPPPQAEAAE----VTCPQEPLAPAAPVPPP-PPSAPASA 446
Score = 45.8 bits (107), Expect = 2e-04
Identities = 154/685 (22%), Positives = 211/685 (30%), Gaps = 199/685 (29%)
Query: 241 FPCKDCGIWYRSERNLQAHLLYYCASRQGT----GSPAAAATD-EKPKETYPNERVCPFP 295
+PC DC +++ +L+ H + R T G +T+ + + + ER P
Sbjct: 144 YPCPDCPKAFKNSSSLRRHRHVHTGERPYTCGVCGKSFTQSTNLRQHQRVHTGERPFRCP 203
Query: 296 QCRKSCPSASSLEIHMRSH---------SGERPFVCLICLSAFTTKANCERHLKVHTDTL 346
C K+ +S+L +H R+H S P F A +RHL+ H+
Sbjct: 204 LCPKTFTHSSNLLLHQRTHGAAPAPGTASAAPPPQSREPGKVFVCDAYLQRHLQPHSPPA 263
Query: 347 SGVCHS----------CGFISTTRDILY-----------SHLVTNHMVCQ-PGSKGEIYS 384
TT +++Y L+ H C P + +
Sbjct: 264 PPAPPPPPPPVVPELFLAAAETTVELVYRCDGCEQGFSSEELLLEHQPCPGPDAAPQPQE 323
Query: 385 PGAGHPATKLPPDSLGSFQQQHTALQGPLASADLGLAPTPSPGLDRKALAE-ATNGEA-- 441
A P PP L A A G + GL R + A G+A
Sbjct: 324 APAEAPKADQPPSPLPQPPPPAAAPAPGFACLPCGKSFRTVAGLSRHQHSHGAAGGQAFR 383
Query: 442 ----------RAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILGPGEP-GPQAPSRTP 490
A LA E AA R + EAA + P EP P AP P
Sbjct: 384 CGSCDGSFPQLASLLAHQQCHVEEAAAGRP-----PPQAEAAEVTCPQEPLAPAAPVPPP 438
Query: 491 SPRSPAPARVK---AELSSPTPGSSPV-----------PGELGLAGALFLPQYVFGPDAA 536
P +PA A AE GSS + P + G G F
Sbjct: 439 PPSAPASAERPYKCAECGKSFKGSSGLRYHLRDHTGERPYQCGECGKAF----------- 487
Query: 537 PPASEILAKMSELVHSRLQQGAGAGAGGAQTGLFPGAPKGATCFECEITFSNVNNYYVHK 596
S +LA +H R+ G A TC +C +TF ++Y H
Sbjct: 488 -KRSSLLA-----IHQRVHTGLRA----------------FTCGQCGLTFKWSSHYQYHL 525
Query: 597 RLYCSGRR---APEDAPAARRPKAPPGPARAPPGQPAEPDAPRSSPGPGAREEGAGGAAT 653
RL+ SG R E A R G+ P A
Sbjct: 526 RLH-SGERPYACGECGKAFRNTSCLRRHRHVHTGE--RPHA------------------- 563
Query: 654 PEDGAGGRGSEGSQSPGSSVDDAEDDPSRTL-CEACNIRFSRHETYTVHKRYYCASR--- 709
G G +Q+ R C C F+ +H+R + A R
Sbjct: 564 ----CGVCGKSFAQTSNLRQHQRVHTGERPFRCPLCPKTFTHSSNLLLHQRTHSAERPFT 619
Query: 710 --------------------HDP---PP--RRPAAPPGPPGP----AAPP---------- 730
H P PP PAA P PP P APP
Sbjct: 620 CPICGRGFVMAAYLQRHLRTHAPANTPPSTTAPAAGPQPPAPLAAARAPPATQDVHVLPH 679
Query: 731 ---------------APS--PAAP-----VRTRRRRKLYELHAAGAPPPPPPGHAPAPES 768
APS PAAP + + + L + ++ PP PPP AP
Sbjct: 680 LQATLSLEVAGGTAQAPSLGPAAPNSQTFLLVQTAQGLQLIPSSVQPPTPPPPPAPPKLI 739
Query: 769 PRPGSGSGSGPGLAPARSPGPAADG 793
P S +G+G G A GP A G
Sbjct: 740 LLPSSSAGAGGGRA---RQGPRAVG 761
Score = 40.8 bits (94), Expect = 0.006
Identities = 32/102 (31%), Positives = 45/102 (44%), Gaps = 3/102 (2%)
Query: 902 PAPAPAASPQPGSRGPRDGLGPEPQEPPPGPPPSPAAAPEAVPPPPAPPSYSDKGVQTPS 961
P P P A+PQP +P P P PPP PAAAP A P S + V S
Sbjct: 311 PCPGPDAAPQPQEAPAEAPKADQPPSPLPQPPP-PAAAP-APGFACLPCGKSFRTVAGLS 368
Query: 962 KGTPAPLPNGNHRY-CRLCNIKFSSLSTFIAHKKYYCSSHAA 1002
+ + G + C C+ F L++ +AH++ + AA
Sbjct: 369 RHQHSHGAAGGQAFRCGSCDGSFPQLASLLAHQQCHVEEAAA 410
Score = 35.8 bits (81), Expect = 0.21
Identities = 72/316 (22%), Positives = 102/316 (32%), Gaps = 71/316 (22%)
Query: 720 PPGPPGPAAPPA----PSPAAPVRTRRRRKLYEL-----HAAGAPPPPPPGHAPAPESPR 770
PP PP P APP PS +A R R+ AG P PG +
Sbjct: 726 PPTPPPPPAPPKLILLPSSSAGAGGGRARQGPRAVGKAGQGAGVVWLPGPGGLGVQGAAS 785
Query: 771 PGSGSGSGPGLAPARSPGPAADGPIDLS---KKPRRPLPGAPAPALADYHECTACR---- 823
G+ SG+G L ++ G GP ++S +P RP P L E T +
Sbjct: 786 AGA-SGTGQSLIVLQNVGGGEAGPQEMSGVQLQPLRPAPEVTTVQLQPAQEVTTVQLQPA 844
Query: 824 ----------------VSFHSLEAYLAHKKYSCPAAPPPGALGLPAAACPYC-------- 859
V + L++ A P L + + A
Sbjct: 845 QEVTTVQLQPAQEVTTVQLQPVAGQLSNSSGGAVATEAPNLLVVQSGAAEELLTGPGPGE 904
Query: 860 -----PPNGPVRGDLLEHFRLAHGLLLGAPLAG-PGVEAR---TPADRGPSPAPAPAASP 910
G V+ L E + GL L+G G + R + P P A+
Sbjct: 905 AGDGEASTGVVQDVLFETLQTDEGLQSVLVLSGADGEQTRLCVQEVETLPPGLTEPPATG 964
Query: 911 QPGSR--------------GPRDGLGPEPQEPPPGPPPSPAAAPEAVPPPPAP------P 950
PG + G G + PP PA+ P +P PA P
Sbjct: 965 PPGQKLLIIRSAPATELLDSSNTGGGTATLQLLAPPPSGPASGPAGLPGAPASQMVQVVP 1024
Query: 951 SYSDKGVQTPSKGTPA 966
+ + GV TP +G P+
Sbjct: 1025 AGAGPGVMTP-QGLPS 1039
Score = 34.7 bits (78), Expect = 0.46
Identities = 34/121 (28%), Positives = 42/121 (34%), Gaps = 32/121 (26%)
Query: 776 GSGPGLAPARSPGPAADGPIDLSKKPRRPLPGAPAPALADYHECTACRVSF-------HS 828
GS +APA + A + +P P APAPA +EC C SF H
Sbjct: 3 GSHADMAPASTAEGAGE----------KPGPAAPAPA--AQYECGECGKSFRWSSRLLHH 50
Query: 829 LEAYLAHKKYSCPAAPPP------------GALGLPAAACPYCPPNGPVRGDLLEHFRLA 876
+ + Y CP P G G CP C P R LL+ R
Sbjct: 51 QRTHTGERPYKCPDCPKAFKGSSALLYHQRGHTGERPYQCPDC-PKAFKRSSLLQIHRSV 109
Query: 877 H 877
H
Sbjct: 110 H 110
Score = 32.7 bits (73), Expect = 1.8
Identities = 43/164 (26%), Positives = 51/164 (31%), Gaps = 35/164 (21%)
Query: 817 HECTACRVSFHSLEAYLAHKKYSCPAAPPPGALGLPAAACPYCPPNGPVRGDLLEHFRLA 876
H C C SF H++ P CP CP +LL H R
Sbjct: 562 HACGVCGKSFAQTSNLRQHQRVHTGERP---------FRCPLCPKTFTHSSNLLLHQRTH 612
Query: 877 HGLL-LGAPLAGPG----------VEARTPADRGPSPAPAPAASPQPGSRGPRDGLGPEP 925
P+ G G + PA+ PS APAA PQP P P
Sbjct: 613 SAERPFTCPICGRGFVMAAYLQRHLRTHAPANTPPSTT-APAAGPQP----------PAP 661
Query: 926 QEPPPGPPPSPAAAPEAVPPPPAPPSYSDKG--VQTPSKGTPAP 967
PP + +P A S G Q PS G AP
Sbjct: 662 LAAARAPPATQDV--HVLPHLQATLSLEVAGGTAQAPSLGPAAP 703
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 97.1 bits (240), Expect = 8e-20
Identities = 171/656 (26%), Positives = 206/656 (31%), Gaps = 175/656 (26%)
Query: 376 PGSKGEIYSPGAGHPATKLPPDSLGSFQQQHTALQGPLASADLGLAPTPSPGLDRKALAE 435
PG+KG SPG+ P K P + P A G+ P P
Sbjct: 535 PGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGP--------- 585
Query: 436 ATNGEARAEPLAQNGGSSEPPAA--PRSIKVEAVEEPEAAPILGPGEPGPQAPSRTPSPR 493
G A A G PP A P EA + P GE G Q P+ +P +
Sbjct: 586 --KGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQ 643
Query: 494 S-PAPARVKAELSSP----TPGSSPVPGELGLAGALFLP--QYVFGP------------- 533
P PA E P PG PG G G P + V GP
Sbjct: 644 GLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAP 703
Query: 534 -------DAAPPASEILAKMSELVHSRLQQGAGAGAGGAQTGLFPGAPKGATCFECEITF 586
DA P + L ++GA AG G + PKGA
Sbjct: 704 GNDGAKGDAGAPGAPGSQGAPGLQGMPGERGA-AGLPGPKGDRGDAGPKGA--------- 753
Query: 587 SNVNNYYVHKRLYCSGRRAPEDAPAARRPKAPPGPARAP-------PGQPAEPDAPRSSP 639
G + P PPGPA AP P PA P R +P
Sbjct: 754 --------------DGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAP 799
Query: 640 GPGAREEGAGGAATPEDGAGGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYT 699
G + G G P AG G++G PG A+ +P
Sbjct: 800 G----DRGEPGPPGPAGFAGPPGADGQ--PG-----AKGEPG------------------ 830
Query: 700 VHKRYYCASRHDPPPRRPAAPPGPPGPAAPPAP--SPAAPVRTRRRRKLYELHAAGAP-- 755
D + A PPGP GPA PP P + AP R A G P
Sbjct: 831 -----------DAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGA 879
Query: 756 -----PPPPPGHAPAPESPRP-GSGSGSGP--GLAPARSPG----PAADGPIDLSKKPRR 803
PP P G+A P P P G G GP PA PG P GP P
Sbjct: 880 AGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGA 939
Query: 804 P----LPGAPAPALADYHECTACRVSFHSLEAYLAHKKYSCPAAP--PPGALGLPAAACP 857
PG P P + A + L + + P PG G P+ A
Sbjct: 940 DGPAGAPGTPGP------QGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQG-PSGASG 992
Query: 858 YCPPNGPVRGDLLEHFRLAHGLLLGAP-LAGPGVEARTPADRGPSPAPAPAASP----QP 912
P GP +G P LAGP P + G AP SP P
Sbjct: 993 ERGPPGP----------------MGPPGLAGP------PGESGREGAPGAEGSPGRDGSP 1030
Query: 913 GSRGPRDGLGPEPQEPPPGPPPSPAAAPEAVPPPPAPPSYSDKGVQTPSKGTPAPL 968
G++G R GP PPG P +P A P P P S +T G P+
Sbjct: 1031 GAKGDRGETGP---AGPPGAPGAPGA-----PGPVGPAGKSGDRGETGPAGPAGPV 1078
Score = 95.5 bits (236), Expect = 2e-19
Identities = 155/582 (26%), Positives = 184/582 (31%), Gaps = 157/582 (26%)
Query: 426 PGLDRKALAEATNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILGPGEPGPQA 485
PG A A +G A G + PP P ++ + EA P G GPQ
Sbjct: 313 PGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKG----EAGPQGPRGSEGPQG 368
Query: 486 PSRTPSPRSPAPARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGPDAAPPASEILAK 545
P P PA A A PG+ PG G GA + P A P+
Sbjct: 369 VRGEPGPPGPAGAAGPA----GNPGADGQPGAKGANGAPGIAGAPGFPGARGPSG----- 419
Query: 546 MSELVHSRLQQGAGAGAGGAQTGLFPGAPKGATCFECEITFSNVNNYYVHKRLYCSGRRA 605
QG G G PGAP G
Sbjct: 420 ---------PQGPGGPPGPKGNSGEPGAPGS------------------------KGDTG 446
Query: 606 PEDAPAARRPKAPPGP--------ARAPPGQPAEPDAPRSSPGPGARE-EGAGGAATPED 656
+ P + PPGP AR PG P P GPG+R GA G A P+
Sbjct: 447 AKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKG 506
Query: 657 GAGGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRR 716
AG RGS G P S +A L A + S P P
Sbjct: 507 PAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGL---------------TGSPGSPGPDG 551
Query: 717 PAAPPGP------PGPAAPPAPSPAAPVRTRRRRKLYELHAAGAP--------PPPP--- 759
PPGP PGP PP A V K AAG P P PP
Sbjct: 552 KTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPK----GAAGEPGKAGERGVPGPPGAV 607
Query: 760 -----PGHAPAPESPRPGSGSGSGPGLAPARSPG----PAADGPIDLSKKP-RRPLP--- 806
G A A P P +G PA SPG P GP + KP + +P
Sbjct: 608 GPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDL 667
Query: 807 GAPAPALADYHECTACRVSFHSLEAYLAHKKYSCPAAP--PPGALGLPAAACPYCPPNGP 864
GAP P+ A + + P P P GA G P N
Sbjct: 668 GAPGPSGA------------RGERGFPGERGVQGPPGPAGPRGANGAPG--------NDG 707
Query: 865 VRGDLLEHFRLAHGLLLGAPLA-----GPGVEARTPADRGPSPAPAP----------AAS 909
+GD GAP A PG++ P +RG + P P A
Sbjct: 708 AKGD------------AGAPGAPGSQGAPGLQG-MPGERGAAGLPGPKGDRGDAGPKGAD 754
Query: 910 PQPGSRGPRDGLGPEPQEPPPGPPPSPAAAPEAVPPPPAPPS 951
PG G R GP PPGP +P E+ P PA P+
Sbjct: 755 GSPGKDGVRGLTGP---IGPPGPAGAPGDKGESGPSGPAGPT 793
Score = 79.7 bits (195), Expect = 1e-14
Identities = 154/588 (26%), Positives = 191/588 (32%), Gaps = 163/588 (27%)
Query: 411 GPLASADLG--LAPTPSPGLDRKALAEATNGEARAEPLAQNG--GSSEPPAAPRSIKVEA 466
GP LG AP S G D K+ T G + P+ +G G PP AP +
Sbjct: 148 GPPGPPGLGGNFAPQLSYGYDEKS----TGGISVPGPMGPSGPRGLPGPPGAPGP---QG 200
Query: 467 VEEPEAAPILGPGEPGPQAPSRTPSPRSPAPARVKAELSSPTPGSSPVPGELGLAGALFL 526
+ P P GEPG P P P P + + + PG PGE G G
Sbjct: 201 FQGPPGEP----GEPGASGPMGPRGPPGP-PGKNGDDGEAGKPGR---PGERGPPG---- 248
Query: 527 PQYVFGPDAAPPASEILAKMSELVHSRLQQGAGAGAGGAQTGLFPGAPKGATCFECEITF 586
P + L + L + +G +G GA+ P PKG
Sbjct: 249 ----------PQGARGLPGTAGLPGMKGHRGF-SGLDGAKGDAGPAGPKGEP-------- 289
Query: 587 SNVNNYYVHKRLYCSGRRAPEDAPAARRPKAPPGPARAPPGQPAEPDAPRSSPGP-GAR- 644
G AP P+ PG R PG +PGP GAR
Sbjct: 290 ---------------GSPGENGAPGQMGPRGLPGE-RGRPG----------APGPAGARG 323
Query: 645 EEGAGGAATPEDGAGGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRY 704
+GA GAA P G G G PG+ E P
Sbjct: 324 NDGATGAAGPPGPTGPAGPPGF--PGAVGAKGEAGPQ----------------------- 358
Query: 705 YCASRHDPPPRRPAAPPGPPGPA--APPAPSPAAPVRTRRRRKLYELHAAGAPPPPPPGH 762
R P+ PGPPGPA A PA +P A + + AGAP P
Sbjct: 359 --GPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARG 416
Query: 763 APAPESPR--PGSGSGSGPGLAPARSPGPAADG---PIDLSKKPRRPLPGAPAPALADYH 817
P+ P PG SG AP A G P+ + G P PA
Sbjct: 417 PSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQ--------GPPGPA----- 463
Query: 818 ECTACRVSFHSLEAYLAHKKYSCPAAPPPGALGLPAAACPYCPPNGPVRGDLLEHFRLAH 877
++ A PG GLP P G G F A
Sbjct: 464 -----------------GEEGKRGARGEPGPTGLPG-------PPGERGGPGSRGFPGAD 499
Query: 878 GLLLGAPLAGPGVEARTPADRGPSPAPAPAASP-------------QPGSRGPRDGL--- 921
G+ A GP E +P GP +P A P PGS GP DG
Sbjct: 500 GV---AGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGP-DGKTGP 555
Query: 922 -GPEPQEPPPGPPPSPAAAPEA-VPPPPAPPSYSDKGVQTPSKGTPAP 967
GP Q+ PGPP P A +A V P P + + + +G P P
Sbjct: 556 PGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGP 603
Score = 72.4 bits (176), Expect = 2e-12
Identities = 158/623 (25%), Positives = 195/623 (31%), Gaps = 171/623 (27%)
Query: 376 PGSKGEIYSPGAGHPA-TKLPPDSLGSFQQQH-------TALQGPLASADLGLAPTPSPG 427
PGSKG+ + G P + PP G ++ T L GP G PG
Sbjct: 439 PGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERG-GPGSRGFPG 497
Query: 428 LDRKALAEATNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAP-ILGP----GEPG 482
D A + GE + A GS P + + +P GP G PG
Sbjct: 498 ADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPG 557
Query: 483 PQAPSRTPSPRSPAPARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGPDAAPPASEI 542
P P P P AR +A + PG GE G AG +P P A PA +
Sbjct: 558 PAGQDGRPGPPGPPGARGQAGVMG-FPGPKGAAGEPGKAGERGVPG---PPGAVGPAGK- 612
Query: 543 LAKMSELVHSRLQQGAGAGAGGAQTGLFPGAPKGATCFECEITFSNVNNYYVHKRLYCSG 602
G GAQ P P G G
Sbjct: 613 -----------------DGEAGAQGPPGPAGPAGER-----------------------G 632
Query: 603 RRAPEDAPAARRPKAPPGPARAPPGQPAEPDAPRS--SPGP-GAREE----GAGGAATPE 655
+ P +P + P GP G+P E P +PGP GAR E G G P
Sbjct: 633 EQGPAGSPGFQGLPGPAGPP-GEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPP 691
Query: 656 DGAGGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPR 715
AG RG+ G+ + DA + A ++ P R
Sbjct: 692 GPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGM------------------PGER 733
Query: 716 RPAAPPGPPGPAAPPAPSPA--APVRTRRRRKLYELHAAGAPPPPPPGHAPAPESPRPGS 773
A PGP G P A +P + R P PPG A AP G
Sbjct: 734 GAAGLPGPKGDRGDAGPKGADGSPGKDGVRGL--------TGPIGPPGPAGAP-----GD 780
Query: 774 GSGSGPGLAPARSPGPAADGPIDLSKKPR-RPLPGAPAPALADYHECTACRVSFHSLEAY 832
SGP GPA GP P R PG P PA
Sbjct: 781 KGESGPS-------GPA--GPTGARGAPGDRGEPGPPGPA-------------------- 811
Query: 833 LAHKKYSCPAAPPPGALGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGPGVEA 892
A PPGA G P A P + +GD AGP
Sbjct: 812 --------GFAGPPGADGQPGAKGE--PGDAGAKGD-----------------AGP---- 840
Query: 893 RTPADRGPSPAPAPAASP-QPGSRGPRDGLGPEPQEPPPGP-----PPSPAAAPEAVPPP 946
P GP+ P P + PG++G R GP PG PP P+ A PP
Sbjct: 841 --PGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSG--NAGPPG 896
Query: 947 PAPPSYSDKGVQTPSKGTPAPLP 969
P P+ + G + PA P
Sbjct: 897 PPGPAGKEGGKGPRGETGPAGRP 919
Score = 69.7 bits (169), Expect = 1e-11
Identities = 110/431 (25%), Positives = 138/431 (32%), Gaps = 109/431 (25%)
Query: 377 GSKGEIYSPGAGHPATKLPPDSLGSFQQQHTALQGPLASADLGLAPTPSPGLDRKALAEA 436
G+KG+ PG PA PP +G+ + P A G A P A
Sbjct: 833 GAKGDAGPPGPAGPAG--PPGPIGN-------VGAPGAKGARGSAGPPG----------A 873
Query: 437 TNGEARAEPLAQNG--GSSEPPAAPRSIKVEAVEEP--EAAPILGPGEPGPQAPSRTPSP 492
T A + G G++ PP P E + P E P PGE GP P
Sbjct: 874 TGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGP------ 927
Query: 493 RSPAPARVKAELSSPTPGSSP-VPGELGLAG---ALFLPQY--------VFGPDAAPPAS 540
P PA K + P +P PG G+AG + LP + GP P
Sbjct: 928 --PGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPG-- 983
Query: 541 EILAKMSELVHSRLQQGAGAGAGGAQTGLFPGAPKGATCFECEITFSNVNNYYVHKRLYC 600
+QG +GA G + P P G E
Sbjct: 984 --------------KQGP-SGASGERGPPGPMGPPGLAGPPGESGREGAPG--------A 1020
Query: 601 SGRRAPEDAPAARRPKAPPGPARAPPGQPAEPDAPRSSPGPGAR-----EEGAGGAATPE 655
G + +P A+ + GPA PPG P P AP GP + E G G A P
Sbjct: 1021 EGSPGRDGSPGAKGDRGETGPA-GPPGAPGAPGAP-GPVGPAGKSGDRGETGPAGPAGPV 1078
Query: 656 DGAGGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPP- 714
G RG G Q P + + R + H+ + PP
Sbjct: 1079 GPVGARGPAGPQGPRGDKGETGEQGDRGI--------------KGHRGFSGLQGPPGPPG 1124
Query: 715 ----------RRPAAPPGPPGPAAPPA-------PSPAAPVRTRRRRKLYELHAAGAPPP 757
PA P GPPG A P P P P R R + G P P
Sbjct: 1125 SPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTG--DAGPVGPPGP 1182
Query: 758 PPPGHAPAPES 768
P P P P S
Sbjct: 1183 PGPPGPPGPPS 1193
Score = 67.8 bits (164), Expect = 5e-11
Identities = 108/410 (26%), Positives = 132/410 (32%), Gaps = 105/410 (25%)
Query: 601 SGRRAPEDAPAARRPKAPPGPARAP--PGQPAEPDAPRSSPGPGAREEGAGGAATP---- 654
+G P+ R P+ P GP PGQP P P PGP G GG P
Sbjct: 108 TGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLP-GPPGPPGPPG-PPGLGGNFAPQLSY 165
Query: 655 ---EDGAGGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHD 711
E GG G P S P +
Sbjct: 166 GYDEKSTGGISVPGPMGP-SGPRGLPGPPGAPGPQG----------------------FQ 202
Query: 712 PPPRRPAAP--PGPPGPAAPPAPSPAAPVRTRRRRKLYELHAAGAPPPPPPGHAPAPESP 769
PP P P GP GP PP P K + AG P P P P+
Sbjct: 203 GPPGEPGEPGASGPMGPRGPPGPP----------GKNGDDGEAGKPGRPGERGPPGPQGA 252
Query: 770 RPGSGSGSGPGL-------------------APARSPGPAADGPIDLSKKPR-----RPL 805
R G+ PG+ P PG + PR R
Sbjct: 253 RGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGR 312
Query: 806 PGAPAPALADYHECTACRVSFHSLEAYLAHKKYSCPAAPP--PGALGLPAAACPYCP--P 861
PGAP PA A ++ + PA PP PGA+G A P P
Sbjct: 313 PGAPGPAGARGND---------GATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGS 363
Query: 862 NGP--VRGDLLEHFRLAHGLLLGAPLAGPGVEARTPADRGPSPAPAPAASPQ-PGSRGPR 918
GP VRG+ P PG + + P +G + AP A +P PG+RGP
Sbjct: 364 EGPQGVRGEPGPPGPAG----AAGPAGNPGADGQ-PGAKGANGAPGIAGAPGFPGARGPS 418
Query: 919 DGLGPEPQEPPPGPPPSPAAAPEAVPPPPAPPSYSDKGVQTPSKGTPAPL 968
GP+ PPGP + P AP S D G +KG P P+
Sbjct: 419 ---GPQGPGGPPGPKGNSG-------EPGAPGSKGDTG----AKGEPGPV 454
Score = 50.8 bits (120), Expect = 6e-06
Identities = 106/416 (25%), Positives = 125/416 (30%), Gaps = 127/416 (30%)
Query: 376 PGSKGEIYSPGA-GHPATKLPPDSLGSFQQQHTALQGPLASADLGLAPTPSPGLDRKALA 434
PG G + +PGA G + PP + G F + P S + G P PG K
Sbjct: 850 PGPIGNVGAPGAKGARGSAGPPGATG-FPGAAGRVGPPGPSGNAG--PPGPPGPAGKEGG 906
Query: 435 EATNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAP-------------------- 474
+ GE G PP + P AP
Sbjct: 907 KGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQ 966
Query: 475 --------ILGP-GEPGPQAPSRTPSPRSPAPARVKAELSSPTPGSSPVPGELGLAGALF 525
+ GP GEPG Q PS R P L+ P PG S G G GA
Sbjct: 967 RGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGP-PGES---GREGAPGAEG 1022
Query: 526 LPQYVFGPDAAPPASEILAKMSELVHSRLQQGAGA--GAGGAQTGLFPGAPKGATCFECE 583
P G D +P A R + G GA GA P P G + E
Sbjct: 1023 SP----GRDGSPGAK----------GDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGE 1068
Query: 584 ITFSNVNNYYVHKRLYCSGRRAPEDAPAARRPKAPPGPARAPPGQPAE------------ 631
+G P AR P P GP R G+ E
Sbjct: 1069 TG--------------PAGPAGPVGPVGARGPAGPQGP-RGDKGETGEQGDRGIKGHRGF 1113
Query: 632 -----PDAPRSSPGPGAREEGAGGAATPEDGAGGRGSEGSQ-SPGSSVDDAEDDPSRTLC 685
P P SPG E+G GA+ P AG RG GS +PG + P
Sbjct: 1114 SGLQGPPGPPGSPG----EQGPSGASGP---AGPRGPPGSAGAPGKDGLNGLPGPI---- 1162
Query: 686 EACNIRFSRHETYTVHKRYYCASRHDPPPR------RPAAPPGPPGPAAPPAPSPA 735
P PR P PPGPPGP PP P A
Sbjct: 1163 ------------------------GPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSA 1194
Score = 33.1 bits (74), Expect = 1.3
Identities = 16/52 (30%), Positives = 21/52 (40%), Gaps = 1/52 (1%)
Query: 900 PSPAPAPAASPQPGSRGPRDGLGPEPQEPPPGPPPSPAAAPE-AVPPPPAPP 950
P + +P G GP+ GP P GPP + +P PP PP
Sbjct: 96 PDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPP 147
Score = 31.6 bits (70), Expect = 3.9
Identities = 25/87 (28%), Positives = 33/87 (37%), Gaps = 7/87 (8%)
Query: 892 ARTPADRGPSPAPAPAASPQP-GSRGP-----RDGLGPEPQEPPPGPPPSPAAAPEAVPP 945
+ +P D+ + P P G RGP RDG+ +P P P PP P P
Sbjct: 99 SESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGN 158
Query: 946 PPAPPSYSDKGVQTPSKGTPAPL-PNG 971
SY T P P+ P+G
Sbjct: 159 FAPQLSYGYDEKSTGGISVPGPMGPSG 185
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 92.4 bits (228), Expect = 2e-18
Identities = 110/379 (29%), Positives = 125/379 (32%), Gaps = 84/379 (22%)
Query: 634 APRSSPGPGAREEGAGGAATPEDGAGGR---GSEGSQSPGSSVDDAEDDPSRTLCEACNI 690
A + GP A EGA GAA PE GR G G Q PG
Sbjct: 68 AGAAGAGPAAPAEGAPGAA-PEPPPAGRARPGGGGPQRPGP------------------- 107
Query: 691 RFSRHETYTVHKRYYCASRHDPPPRRPAAPPGPPGPAAPPAPSPAAPVRTRRRRKLYELH 750
P PRRP P GP PAA P P +
Sbjct: 108 ---------------------PSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAV 146
Query: 751 AAGAPPPPPPGHA----PAPESPRPGSGSGSGPGLAPARSPG-PAADGPIDLSKKPRRPL 805
AAG P P P G A PA + R G G G GPG P PG PA G L
Sbjct: 147 AAG-PEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALL 205
Query: 806 PG--APAPALADYHECTACRVSFHSLEA---------YLAHKKYSCPAAPPPGALGLPAA 854
A APA++ + A + A ++ PAAP P A PAA
Sbjct: 206 NSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAA 265
Query: 855 ACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGPGVEARTPADRGPSPAPAPAASPQPGS 914
PP P L G AP P A+ G +PAPAPAA G
Sbjct: 266 PAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGV 325
Query: 915 RGPRDGLGPEPQEPPPG-------------PP---------PSPAAAPEAVPPPPAPPSY 952
G + G G P PG PP P+ AA + P
Sbjct: 326 SG-QPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALP 384
Query: 953 SDKGVQTPSKGTPAPLPNG 971
S V P+ GTP LP G
Sbjct: 385 SPAAVPPPAPGTPTGLPKG 403
Score = 78.6 bits (192), Expect = 3e-14
Identities = 107/374 (28%), Positives = 133/374 (35%), Gaps = 82/374 (21%)
Query: 601 SGRRAPEDAPAARRPKAPPGPARAPPGQPAEPD--APRSSPGPG-----------AREEG 647
+G AP PAA A P PA A P +PA P A R+ PGPG + G
Sbjct: 134 AGSCAP--VPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAG 191
Query: 648 AGGAATPEDGAGGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCA 707
G A T A S + +P S+ + P+ L TV +
Sbjct: 192 PGAAQTLNGSAALLNSHHAAAPAVSL--VNNGPAALLPLP-----KPAAPGTVIQ----- 239
Query: 708 SRHDPPPRRPAAPPGPPGPAAPPAPSPAAPVRTRRRRKLYELHAAGAPPPP--------P 759
PP AAPP P P+ P AP+PAAP AA PPPP P
Sbjct: 240 ---TPPFVGAAAPPAPAAPSPPAAPAPAAP-------------AAAPPPPPPAPATLARP 283
Query: 760 PGHAPAPESPRP------GSGSGSGPGLAPARSPGPAADGPIDLSKKPRRPLPGAPAPAL 813
PGH P + P + +G G APA P PAA GP +S +P PGA A A
Sbjct: 284 PGHPAGPPTAAPAVPPPAAAQNGGSAGAAPA--PAPAAGGPAGVSGQPG---PGAAAAAP 338
Query: 814 ADYHECTACRVSFHSLEAYLAHKKYSCPAAPPPGALGLPAAACPYCPPNGPVRGDLLEHF 873
A A A PP A L AA+ P V G ++
Sbjct: 339 A---------------PGVKAESPKRVVQAAPPAAQTL-AASGPASTAASMVIGPTMQG- 381
Query: 874 RLAHGLLLGAPLAGPGVEARTPADRGPSPAPAPAASPQPGSRGPRDGLGPEPQEPP-PGP 932
A P PG P + + + +P + G R L P P P P
Sbjct: 382 --ALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQP 439
Query: 933 PPSPAAAPEAVPPP 946
P +P PP
Sbjct: 440 PQNPTNIQNFQLPP 453
Score = 60.1 bits (144), Expect = 1e-08
Identities = 103/386 (26%), Positives = 126/386 (32%), Gaps = 97/386 (25%)
Query: 408 ALQGPLASADLGLAPTPSPGLDRKALAEATNGEARAEPLAQN-----GGSSEP-PAAPRS 461
A G L + + +P + G A AE G A P A GG P P +PR
Sbjct: 53 AAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRR 112
Query: 462 IKVEAVEEPEAAPILGP--GEPGPQAP---------SRTPSPRSPAPARVKAELSS---- 506
V A P AA + P G G AP P+P PA A L++
Sbjct: 113 PLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGP 172
Query: 507 -----PTPGSSPVPGELGLAGALFLPQYVFGPDAAPPASEILAKMSELVHSRLQQGAGAG 561
P PG P PG+ A P A++ L + L++S
Sbjct: 173 GPGPGPGPGPGPGPGK----------------PAGPGAAQTLNGSAALLNSHHAAAPAVS 216
Query: 562 -AGGAQTGLFPGAPKGATCFECEITFSNVNNYYVHKRLYCSGRRAPED-APAARRPKAPP 619
L P PK A T V S AP APAA P PP
Sbjct: 217 LVNNGPAALLP-LPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPP 275
Query: 620 GPA--RAPPGQPA-EPDAPRSSPGPGAREEG--AGGAATPEDGAGG-RGSEGSQSPGSSV 673
PA PPG PA P A + P P A + G AG A P AGG G G PG++
Sbjct: 276 APATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAA 335
Query: 674 -----DDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRPAAPPGP----- 723
+ P R + A PP + A GP
Sbjct: 336 AAPAPGVKAESPKRVVQAA------------------------PPAAQTLAASGPASTAA 371
Query: 724 ------------PGPAAPPAPSPAAP 737
P PAA P P+P P
Sbjct: 372 SMVIGPTMQGALPSPAAVPPPAPGTP 397
Score = 48.1 bits (113), Expect = 4e-05
Identities = 80/315 (25%), Positives = 98/315 (31%), Gaps = 80/315 (25%)
Query: 385 PGAGHPATKLPPDSLGSFQQQHTALQGPLASADLGLAPTPSPGLDR-----------KAL 433
P PA P +L A GP G P P PG AL
Sbjct: 152 PAPAGPAKPAGPAALA-------ARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAAL 204
Query: 434 AEATNGEARAEPLAQNGGSS----EPPAAPRSIK-----VEAVEEPEAAPILGPGEPGPQ 484
+ + A A L NG ++ PAAP ++ V A P A P P P
Sbjct: 205 LNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPA 264
Query: 485 APSRTPSPRSPAP---ARVKAELSSPTPGSSPVPGEL-----GLAGALFLPQYVFGPDAA 536
AP+ P P PAP AR + P + VP G AGA P P A
Sbjct: 265 APAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAP----APAAG 320
Query: 537 PPASEILAKMSELVHSRLQQGAGAGAGGAQTGLFPGAPKGATCFECEITFSNVNNYYVHK 596
PA Q G GA A G+ +PK
Sbjct: 321 GPAG-----------VSGQPGPGAAAAAPAPGVKAESPK--------------------- 348
Query: 597 RLYCSGRRAPEDAPAARRPKAPPGPARAPPGQPAEPDAPRSSPGPGAREEGAGGAAT--P 654
R + AP A + A GPA P + P P A A G T P
Sbjct: 349 -------RVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLP 401
Query: 655 EDGAGGRGSEGSQSP 669
+ AG S++P
Sbjct: 402 KGAAGAVTQSLSRTP 416
Score = 47.0 bits (110), Expect = 9e-05
Identities = 29/99 (29%), Positives = 41/99 (41%), Gaps = 2/99 (2%)
Query: 875 LAHGLLLGAPLAGPGVEARTPADRGP--SPAPAPAASPQPGSRGPRDGLGPEPQEPPPGP 932
L + ++ G+P G PA+ P +P P PA +PG GP+ P P+ P
Sbjct: 58 LGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPA 117
Query: 933 PPSPAAAPEAVPPPPAPPSYSDKGVQTPSKGTPAPLPNG 971
P+P AA PP + S + P P P G
Sbjct: 118 GPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAG 156
Score = 38.9 bits (89), Expect = 0.025
Identities = 48/167 (28%), Positives = 54/167 (32%), Gaps = 30/167 (17%)
Query: 810 APALADYHECTACRVSFHSLEAYLAHKKYSCPAAPPPGALGLPAAACPYCPPNGPVRGDL 869
AP + A + H + A + PAAP GA G A P PP G R
Sbjct: 44 APRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPG----AAPEPPPAGRARP-- 97
Query: 870 LEHFRLAHGLLLGAPLAGPGVEARTPADRGPSPA-----PAPAAS-----PQPGSRGPRD 919
G G GP R GP+P P P S P P +
Sbjct: 98 ------GGG---GPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAV-- 146
Query: 920 GLGPEPQEPPPGPPPSPAAAPEAVPPPPAPPSYSDKGVQTPSKGTPA 966
GPEP P P PAA P P P G P G PA
Sbjct: 147 AAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPG---PGPGKPA 190
Score = 35.4 bits (80), Expect = 0.27
Identities = 49/205 (23%), Positives = 66/205 (32%), Gaps = 26/205 (12%)
Query: 385 PGAGHPATKLPPDSLGSFQQQHTALQGPLASADLGLAPTPSPGLDRKALAEATNGEARAE 444
P A + PP + A P A A A P P A G
Sbjct: 231 PAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGP 290
Query: 445 PLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILG-----PGEPGPQAPSRTPSP--RSPAP 497
P A + PP A A P AP G G+PGP A + P+P ++ +P
Sbjct: 291 PTA---APAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESP 347
Query: 498 ARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFG----PDAAPPASEILAKMSELVHSR 553
RV + + P + G A ++ + + G P A PP +
Sbjct: 348 KRV-VQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPA-----------PG 395
Query: 554 LQQGAGAGAGGAQTGLFPGAPKGAT 578
G GA GA T P T
Sbjct: 396 TPTGLPKGAAGAVTQSLSRTPTATT 420
Score = 35.4 bits (80), Expect = 0.27
Identities = 35/117 (29%), Positives = 43/117 (36%), Gaps = 21/117 (17%)
Query: 39 APEAPSPPSADVNSPPPLPPPTSPGGPKELEGQEPEPRPTEEEPGSPWSGPDELEPVVQD 98
AP APSPP+A + P PP P P L RP G P + P P
Sbjct: 251 APAAPSPPAAPAPAAPAAAPPPPPPAPATL------ARPPGHPAGPPTAAPAVPPPAAAQ 304
Query: 99 GQRRIRARLSLA------TGLSWGPFHGSVQ------TRASSPR---QAEPSPALTL 140
A + A G+S P G+ +A SP+ QA P A TL
Sbjct: 305 NGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTL 361
Score = 31.2 bits (69), Expect = 5.1
Identities = 21/60 (35%), Positives = 24/60 (40%), Gaps = 8/60 (13%)
Query: 37 ATAPEAPSPPSADVNSPPPLPPPTSPGGPKELEGQEPEPRPTEEEPGSPWSGPDELEPVV 96
A AP AP+ PS PP P P +P P P PG P +GP P V
Sbjct: 246 AAAPPAPAAPS-----PPAAPAPAAPAAAP--PPPPPAPATLARPPGHP-AGPPTAAPAV 297
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 90.1 bits (222), Expect = 9e-18
Identities = 168/647 (25%), Positives = 195/647 (30%), Gaps = 183/647 (28%)
Query: 350 CHSCGFISTTRDI---LYSHLVTNHMVCQPGSKGEIYSPGAGHPATKLPPDSLGSFQQQH 406
C I + R I L SH T + P ++S G G P ++ P FQ H
Sbjct: 782 CSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSH 841
Query: 407 TALQGPLASADLGLAPTPSPGLDRKALAEATNGEARAEPLAQNGGSSEPPAAPRSIKVEA 466
+ ++SA PSP PL SS P
Sbjct: 842 ---EHSVSSAFKNSCNIPSP-----------------PPLPCTESSSSMPGL-------G 874
Query: 467 VEEPEAAPILGPGEPGPQAPSRT-PSPRSPAPARVKAELSSPTPGSS-PVPGELGLAGAL 524
+ P P+ PG P PS P P + P PG+ P P L AG L
Sbjct: 875 MVPPPPPPL--PGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGIL 932
Query: 525 FLPQYVFGPDAAPPASEILAKMSELVHSRLQQGAGA-------GAGGAQTGLFPGAPKGA 577
LP P A P L + L GAG GAG PGA
Sbjct: 933 PLPPL---PGAGIPPPPPLPGAAIPPPPPLP-GAGIPLPPPLPGAGIPPPPPLPGA---- 984
Query: 578 TCFECEITFSNVNNYYVHKRLYCSGRRAPEDAPAARRPKAPPGPARAPPGQPAEPDA--P 635
G P P A P PP P P P P A P
Sbjct: 985 ------------------------GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 1020
Query: 636 RSSPGPGAREEGAGGAATPEDGAGGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRH 695
P PGA G P G PG+ + P +
Sbjct: 1021 PPPPLPGA------GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI----------- 1063
Query: 696 ETYTVHKRYYCASRHDPPPRRPAA--PPGPPGPAA---PPAPSPAAPVRTRRRRKLYELH 750
PPP P A PP PP P A PP P P A + L
Sbjct: 1064 ---------------PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP-----PLP 1103
Query: 751 AAGAPPPPP-PGHAPAPESPRPGSGSGSGPGLAPARSPGPAADGPIDLSKKPRRPLPGAP 809
G PPPPP PG P P PG+G P L A P P + + P PLPGA
Sbjct: 1104 GVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPP--PLPGAG 1161
Query: 810 APALADYHECTACRVSFHSLEAYLAHKKYSCPAAPPPGALGLPAAACPYCPPNGPVRGDL 869
P PPP LP A P PP V
Sbjct: 1162 IPP-------------------------------PPP----LPGAGIPPPPPLPGV---- 1182
Query: 870 LEHFRLAHGLLLGAPLAGPGVEARTPADRGPSPAPAPAASPQPGSRGPRDGLGPEPQEPP 929
G+ PL G G+ P P P P A P P G+G P P
Sbjct: 1183 --------GIPPPPPLPGVGI---------PPPPPLPGAGIPPPP--PLPGMGIPPAPAP 1223
Query: 930 PGPPPSPAAAPEAVPP---PPAPPSYSDKGVQTPS--KGTPAPLPNG 971
P PPP P + P PP P + TP P PLP+G
Sbjct: 1224 PLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLPSG 1270
Score = 46.6 bits (109), Expect = 1e-04
Identities = 64/251 (25%), Positives = 93/251 (37%), Gaps = 49/251 (19%)
Query: 738 VRTRRRRKLYELHAAGAPPPPPPGHAPAPES--------PRPGSGSGSGPGLAPARSPGP 789
++ +++++ +L A P PP +P P + P G+G PG
Sbjct: 215 LQLQQQQQQQQLQGAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALS 274
Query: 790 A-ADGPIDLSKKPRRPLPGAPAPALADYHECTACRVSFHSLEAYLAHKKYSCPAAPPPGA 848
A +D P L+ +PR P P+P E S PAA P
Sbjct: 275 ALSDLPESLAAEPREPQQ-PPSPGGLPVSEAP------------------SLPAAQPAAK 315
Query: 849 LGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGPG---VEARTPA-DRGPSPAP 904
+ A P+ P GP GAP+ G G E A + P +P
Sbjct: 316 DSPSSTAFPF-PEAGPGEE------------AAGAPVRGAGDTDEEGEEDAFEDAPRGSP 362
Query: 905 APAASPQPGSRGPRDGLGPEPQEPPPGPPPSPAAAPEAVPPPPAPPSYSDKGVQTPS--K 962
+P+ G P+ LG EP+E G P +PAAA P P+ + + TP K
Sbjct: 363 GEEWAPEVGEDAPQR-LGEEPEEEAQG-PDAPAAASLPGSPAPSQRCFKPYPLITPCYIK 420
Query: 963 GTPAPLPNGNH 973
T L + NH
Sbjct: 421 TTTRQLSSPNH 431
Score = 33.1 bits (74), Expect = 1.3
Identities = 38/120 (31%), Positives = 47/120 (39%), Gaps = 12/120 (10%)
Query: 403 QQQHTALQGPLASADLGLAPTPSPG----LDRKALAEATN-GEARAEPLAQNGGSSEPPA 457
QQQ LQG A A +P PG LDR L + GEA P + S+
Sbjct: 220 QQQQQQLQGAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDL 279
Query: 458 APRSIKVEAVEEPEAAPILGPGEPGPQAPSRTPSPRSPAPARVKAELSSPTPGSSPVPGE 517
P S+ E EP+ P PG S PS + PA + S+ P PGE
Sbjct: 280 -PESLAAEP-REPQQPP-----SPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGE 332
Score = 32.3 bits (72), Expect = 2.3
Identities = 76/335 (22%), Positives = 100/335 (29%), Gaps = 109/335 (32%)
Query: 479 GEPGPQAPSRTPSPRSPAPARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGPDAAPP 538
G P AP SP+ A + L P+ G+ PG +P
Sbjct: 228 GAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPG-------------------SPD 268
Query: 539 ASEILAKMSELVHSRLQQGAGAGAGGAQTGLFPGAPKGATCFECEITFSNVNNYYVHKRL 598
+ L+ +S+L S + P P+
Sbjct: 269 TEQALSALSDLPESLAAE--------------PREPQQPP-------------------- 294
Query: 599 YCSGRRAPEDAPAARRPKAPPGPARAPPGQPAEPDAPRSS----PGPGAREEGAGGAATP 654
+P P + P P QPA D+P S+ P G EE AG P
Sbjct: 295 ------SPGGLPVSEAPS-------LPAAQPAAKDSPSSTAFPFPEAGPGEEAAG---AP 338
Query: 655 EDGAGGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPP 714
GAG EG + D ED P R S E + R P
Sbjct: 339 VRGAGDTDEEGEE------DAFEDAP----------RGSPGEEWAPEVGEDAPQRLGEEP 382
Query: 715 RRPAAPPGPPGPAAPPAPSPAAPVRTRRRRKLY-------------ELHAAGAPPPPPPG 761
A GP PAA A P +P ++R K Y +L + P P
Sbjct: 383 EEEA--QGPDAPAA--ASLPGSPAPSQRCFKPYPLITPCYIKTTTRQLSSPNHSPSQSPN 438
Query: 762 HAP-APESPRPGSGSGSGPGLAPARSPGP--AADG 793
+P P P GS LA +P ADG
Sbjct: 439 QSPRIKRRPEPSLSRGSRTALASVAAPAKKHRADG 473
Score = 31.6 bits (70), Expect = 3.9
Identities = 27/79 (34%), Positives = 29/79 (36%), Gaps = 20/79 (25%)
Query: 37 ATAPEAPSPPSADVNSPPPL------PPPTSPGG----PKELEGQ--EPEPRPTEEEPGS 84
A P P P + PPPL PPP PG P L G P P P PG+
Sbjct: 1171 AGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGT 1230
Query: 85 --------PWSGPDELEPV 95
P SGP L V
Sbjct: 1231 GIPPPPLLPVSGPPLLPQV 1249
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 87.8 bits (216), Expect = 5e-17
Identities = 138/592 (23%), Positives = 191/592 (32%), Gaps = 113/592 (19%)
Query: 396 PDSLGSFQQQHTALQGPLASADLGLAPTPSPGLDRKALA---EATNGEARAEPLAQNGGS 452
P S+ S Q + Q P + PT +P D L +A+ + + + + G
Sbjct: 236 PKSISSQQPEKIKSQPPGTGKPIQ-GPTQTPQTDHAKLPLQRDASRPQTKQADIVR--GE 292
Query: 453 SEPPAAPRSIKVEAVEEPEAAPILGPGEPGPQAPSRTPSPRSPAPARVKAELSSPTPGSS 512
S P+ P K +++P PG+P Q P S P PA+ A+ S T +
Sbjct: 293 SVKPSLPSPSK-PPIQQPT------PGKPPAQQPGHEKS--QPGPAKPPAQPSGLTKPLA 343
Query: 513 PVPG----ELGLAGALFLPQYVFGPDAAPPASEILAKMSELVH---SRLQQGAGAGAGGA 565
PG + G P GP A PPA + ++ L Q G G A
Sbjct: 344 QQPGTVKPPVQPPGTTKPPAQPLGP-AKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPA 402
Query: 566 QTGLFPGAPKGATCFECEITFSNVNNYYVHKRLYCSGRRAPEDAPAARRPKAPPGPARAP 625
Q PG K T + P + P PGP + P
Sbjct: 403 QQ---PGPAKPPT-------------------QQVGTPKPLAQQPGLQSPAKAPGPTKTP 440
Query: 626 PGQPAEPDAPRSSPGPGAREEGAGGAATPEDGAGGRGSEGSQSPGSSVDDAEDDPSRTLC 685
QP P GPG G P G Q PG + + S
Sbjct: 441 VQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSA--- 497
Query: 686 EACNIRFSRHETYTVHKRYYCASRHDPPPRRPAAPPGPPGPAAPPAPSPAAPVRTRRRRK 745
PP ++P + PP P PSP P T+ +
Sbjct: 498 -------------------------KPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQ 532
Query: 746 LYELHAAGAPPPPPPGHAPAPESPRPGSGSGSGPGLAPARSPGPAADGPIDLSKKPRRPL 805
A + P P A +S +P S +GSG L P A P K PL
Sbjct: 533 -QPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPL 591
Query: 806 PGAP-----APALADYHECTACRVSFHSLEAYLAHKKYSCPAAPPPGALGLPAAACPYCP 860
P A+++ CT C+ + SL C P P + C C
Sbjct: 592 CNTTELLLHVPEKANFNTCTECQTTVCSL----------CGFNPNPHLTEVKEWLCLNCQ 641
Query: 861 PNGPVRGDLLEHFRLAHGLLLGAPLAGPGVEARTPADRGPSPAPAPAASPQPGSRGPRD- 919
+ GDL L AP+ T A SP P SP+ + +D
Sbjct: 642 MKRALGGDLAPVPSSPQPKLKTAPV------TTTSAVSKSSPQP-QQTSPKKDAAPKQDL 694
Query: 920 GLGPEPQEPPP----------------GPPPSPAAAPEAVPPPPAPPSYSDK 955
PEP++PPP PP + + + A P P+ PS DK
Sbjct: 695 SKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDK 746
Score = 65.1 bits (157), Expect = 3e-10
Identities = 80/301 (26%), Positives = 107/301 (35%), Gaps = 53/301 (17%)
Query: 712 PPPRRPAAPPGPPGPAAPPA-PS----PAA--------PVRTRRRRKLYELHAAGAPPPP 758
PP ++P PGPA PPA PS P A PV+ K A PP
Sbjct: 314 PPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPA 373
Query: 759 PPGHAPAPESPRPGS---GSGSGPGLAPARSPGPA------ADGPIDLSKKPRRPLPG-A 808
+ P S +PG G G PA+ PGPA P L+++P P A
Sbjct: 374 QQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKA 433
Query: 809 PAPALADYHECTACRVSFHSLEAYLAHKKYSCPAAPPPGALGLPAAACPYCPPNGPVRGD 868
P P + ++ + + P PP LP A P GP +
Sbjct: 434 PGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPS---QLPGPAKPPPQQPGPAKPP 490
Query: 869 LLEHFRLAHGLLLGAPLAGPGVEARTPADRGPS-PAPAPAASPQPGSRGPRDGLGPEPQE 927
+ P PG P GP+ P+P S +P S+ P P Q+
Sbjct: 491 PQQPGSAK------PPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQP-GSAKPSAQQ 543
Query: 928 PPPGPPPSPAAAPEAVPP--------PPAPPSYSDKGVQTPSKGTPAPLPNGNHRYCRLC 979
P P P +A ++ P P PP+ S Q PS+G P + C LC
Sbjct: 544 PSPAKP----SAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTI-------CPLC 592
Query: 980 N 980
N
Sbjct: 593 N 593
Score = 50.4 bits (119), Expect = 8e-06
Identities = 28/71 (39%), Positives = 35/71 (49%), Gaps = 4/71 (5%)
Query: 895 PADRGPSPAPAPA---ASPQPGSRGPRDGLGPEPQEPPPGPPPSPAAAPEAVPPPPAPPS 951
PA + PS +P+ + A P+P R + +P PPP PPP P P PPPP PP
Sbjct: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPP-PPPPPPPPPPPPPPPPLPPP 2430
Query: 952 YSDKGVQTPSK 962
S K P K
Sbjct: 2431 TSPKPTILPKK 2441
Score = 49.3 bits (116), Expect = 2e-05
Identities = 138/663 (20%), Positives = 198/663 (29%), Gaps = 124/663 (18%)
Query: 375 QPGSKGEIYSPGAGHPATKLPPDSLGSFQQ--------QHTALQGPLASADLGLAPTPSP 426
QPG K PG G + P + QQ Q LQ P + P P
Sbjct: 385 QPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQP 444
Query: 427 GLDRKALAEATNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILGPGEPGPQAP 486
G + +A G+ A+ Q G + P P K P P GP +P PQ P
Sbjct: 445 GPGKIPAQQAGPGKTSAQ---QTGPTKPPSQLPGPAK-----PPPQQP--GPAKPPPQQP 494
Query: 487 -----------SRTPSPRSPAPARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGPDA 535
S P P+ P PA+ + T S PG + P +
Sbjct: 495 GSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQS 554
Query: 536 APPASEI---LAKMSELVHSRLQQGAGAGAGGA------QTGLFPGAPKGA---TCFECE 583
P S+ V +Q G T L P+ A TC EC+
Sbjct: 555 TKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQ 614
Query: 584 ITFSNVNNYYVHKR---------LYCSGRRA----PEDAPAARRPKAPPGPARAPPGQPA 630
T ++ + + L C +RA P++ +PK P
Sbjct: 615 TTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSA--- 671
Query: 631 EPDAPRSSPGPGAREEGAGGAATPEDGAGGRGSEGSQSPGSSVDDAEDDPSRTLCEACNI 690
+SSP P ++ A P+ P PS
Sbjct: 672 ---VSKSSPQP--QQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPS--------- 717
Query: 691 RFSRHETYTVHKRYYCASRHDPPPRRPAAPPGPPGPAAPPAPSPAAPVRTRRRRK----- 745
A PP + P PP + P+ APV + ++
Sbjct: 718 ----------------AKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVK 761
Query: 746 ----LYELHAAGAPPPPPPG--HAPAPESPRPGSGSGSGPGLAPARSPGPAAD--GPIDL 797
L +A P P + A E P + S P++S P + P D
Sbjct: 762 PTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSA---KPSQSFPPTGEKVSPFD- 817
Query: 798 SKKPRRPLPGAPAPALADYHECTACRVSFHSLEAYLAHKKYSCPAAPPPGALGLPAAACP 857
SK RP + + + + ++ KK +P P A +P + P
Sbjct: 818 SKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGS-P 876
Query: 858 YCPPNGPVRGDLL-------------EHFRLAHGLLLGAPLAGPGVEARTPADR--GPSP 902
P P G + F L G + AP + P T + G
Sbjct: 877 TPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGA 936
Query: 903 APAPAASPQPGSRGPRDGLGPEPQEPPPGPPPSPAAAPEAVPPPPAPPSYSDKGVQTPSK 962
+ AS + G GP Q PG P A AP P PP + + P+K
Sbjct: 937 SIFSQASNLISTAGQP---GPHSQS-GPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAK 992
Query: 963 GTP 965
P
Sbjct: 993 SIP 995
Score = 46.2 bits (108), Expect = 2e-04
Identities = 74/333 (22%), Positives = 109/333 (32%), Gaps = 67/333 (20%)
Query: 446 LAQNGGSSEPPAAPRSIKVEAVEEPEAAPI-LGPGEPGPQAPSRTPSPRSPAPARVKAEL 504
++ G SSE + V+ EEP+ A + P P +P+P P P A
Sbjct: 831 ISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPT---AGQ 887
Query: 505 SSPTPGSSPVPGELGLAGALFLPQYVFGPDAAP--PASEILAKMSELVHSRLQQGAG--- 559
+ PTP SP P E +L L P + P P + K+ S Q +
Sbjct: 888 TVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLIS 947
Query: 560 -AGAGGAQTGLFPGAPKGATCFECEITFSNVNNYYVHKRLYCSGRRAPEDAPAARRPKAP 618
AG G + PGAP K+ + P +AP
Sbjct: 948 TAGQPGPHSQSGPGAPM--------------------KQAPAPSQPPTSQGPPKSTGQAP 987
Query: 619 PGPA---------RAPPGQPAEPDAPR--------SSPGPGAREEGAGGAATPEDGAGGR 661
P PA +AP + EP A + + P ++ A P+
Sbjct: 988 PAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPT 1047
Query: 662 GSEGSQSPGSSVD--------DAEDDPSRTLC-----EACNI-RFSRHETYTVHKRYYCA 707
E S P S+ ++D P+ C + CN+ F+ T + + C
Sbjct: 1048 KLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCL 1107
Query: 708 SRHDPPPRR------PAAPPGPPGPAAPPAPSP 734
+ PP P GP A P P P
Sbjct: 1108 NCQTQRAISGQLGDIRKMPPAPSGPKASPMPVP 1140
Score = 40.0 bits (92), Expect = 0.011
Identities = 192/936 (20%), Positives = 285/936 (30%), Gaps = 208/936 (22%)
Query: 21 AREEVQLVGASHMEQKATAPEAPSPP----SADVNSPPPLPPPTSPGGPKELEGQEPEPR 76
A+ Q G+ + P+A + P P P PPT G P+
Sbjct: 369 AKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVG---------TPK 419
Query: 77 PTEEEPG--SPWSGPDELE-PVVQDGQRRIRARLSLATGLSWGPFHGSV-QTRASSPRQA 132
P ++PG SP P + PV Q G +I A+ + GP S QT + P
Sbjct: 420 PLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQA-------GPGKTSAQQTGPTKPPSQ 472
Query: 133 EPSPALTLLLVDEACWLRTLPQALTEAEANTEIHRKDDALWCRVTKPVPAGGLLSVLLTA 192
P PA + PQ A KP P + +
Sbjct: 473 LPGPA------------KPPPQQPGPA------------------KPPPQQPGSAKPPSQ 502
Query: 193 EPHSTPGHPVKKEPAEPTCPAPAHDLQLLPQQAGMASILATAVINKDVFPCKDCGIWYRS 252
+P ST P + PA+P+ P + QQ G A A + P K
Sbjct: 503 QPGSTKPPPQQPGPAKPS-PQQPGSTKPPSQQPGSAKPSA-----QQPSPAKP------- 549
Query: 253 ERNLQAHLLYYCASRQGTGSPAAAATDEKPKETYPNERVCPFPQCRKSCPSASSLEIHMR 312
A S+ G+G P T P P + P + CP ++ E+ +
Sbjct: 550 ----SAQQSTKPVSQTGSGKPLQPPT-VSPSAKQPPSQGLP----KTICPLCNTTELLL- 599
Query: 313 SHSGERPFVCLICLSAFTTKANCERHLKVHTDTLSGVCHSCGFISTTRDILYSHLVTNHM 372
H E+ + F T C+ + VC CGF + +
Sbjct: 600 -HVPEK--------ANFNTCTECQ----------TTVCSLCGFNPNPHLTEVKEWLCLNC 640
Query: 373 VCQPGSKGEIYS-PGAGHPATKLPP------DSLGSFQQQHTALQGPLA-SADLGLAPTP 424
+ G++ P + P K P S S Q Q T+ + A DL AP P
Sbjct: 641 QMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEP 700
Query: 425 S---PGLDRKALAEATNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILGPGEP 481
P + + L + + +A+ P A + PP P E + AP+
Sbjct: 701 KKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEP-----SVPSEQDKAPVADDKPK 755
Query: 482 GPQAPSRTPSPRSPAPARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGPDAAPPASE 541
P+ T S + A K ++ S S A P D+A P S+
Sbjct: 756 QPKMVKPTTDLVSSSSATTKPDIPSSKVQSQ--------AEEKTTPP--LKTDSAKP-SQ 804
Query: 542 ILAKMSELVHSRLQQGAGAGAGGAQTGLFPGAPKGATCFECEITFSNVNNYYVHKRLYCS 601
E V + A ++ PG P + + ++ V K+
Sbjct: 805 SFPPTGEKVSPFDSKAIPRPASDSKIISHPG-PSSESKGQKQV--DPVQKKEEPKKAQTK 861
Query: 602 GRRAPEDAPAARRPKAPPGPARAPPGQPAEPDAPRSSPGPGAREEGAGGAATPEDGAGGR 661
P+ P + PPGP R GQ P+ SP P +
Sbjct: 862 MSPKPDAKPMPKGSPTPPGP-RPTAGQTV--PTPQQSPKPQEQSR--------------- 903
Query: 662 GSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPR------ 715
S + GS D + P+ F + ++ P P
Sbjct: 904 --RFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPG 961
Query: 716 -------RPAAPPGPPGP-----AAPPAPSPAAPVRTRRRRKLYELHAAGAPPPPPPGHA 763
P+ PP GP APPAP+ + PV+ + E A P
Sbjct: 962 APMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRT 1021
Query: 764 PAPESPRPGSGSGSGPGLAPARSPGPAADGPIDLSKKPRRPLP--------GAPAPALAD 815
+ P P S S A ++ S KP P G+ P +
Sbjct: 1022 ETEKKPPPIKDSKS----LTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDP--PN 1075
Query: 816 YHECTACRVSFHSLEAYLAHKKYSCPAAPPPGALGLPAAACPYCPPNGPVRGDLLEHFRL 875
++ CT C+ +L C P P + C C + G L +
Sbjct: 1076 FNTCTECKNQVCNL----------CGFNPTPHLTEIQEWLCLNCQTQRAISGQLGD---- 1121
Query: 876 AHGLLLGAPLAGPGVEARTPADRGP--SPAPAPAAS 909
+ PA GP SP P P S
Sbjct: 1122 --------------IRKMPPAPSGPKASPMPVPTES 1143
Score = 38.9 bits (89), Expect = 0.025
Identities = 36/121 (29%), Positives = 42/121 (34%), Gaps = 34/121 (28%)
Query: 712 PPPRRPAAPPGPPGPAAPPAPSPAAPVRTRRRRK-------------LYE---------- 748
PPP P PP PP P PP P P +P T +K L++
Sbjct: 2408 PPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAV 2467
Query: 749 LHAAGAPPPPPPGHAPAPESPRPGSGSGSGPGLAPARSPGPAADGPIDLSKKPRRPLPGA 808
L + G P AP P P+P S GL P P SK P P P
Sbjct: 2468 LRSNGLPVTRICTTAPPPVPPKP---SSIPSGLVFTHRPEP--------SKPPIAPKPVI 2516
Query: 809 P 809
P
Sbjct: 2517 P 2517
Score = 36.2 bits (82), Expect = 0.16
Identities = 26/71 (36%), Positives = 30/71 (42%), Gaps = 9/71 (12%)
Query: 721 PGPPGPAAPPAPS--PAAPVRTRRRRKLYELHAAGAPPPPPPGHAPAPESPRPGSGSGSG 778
P P+ P+ S PA P R R ++ A PPPPPP P P P P
Sbjct: 2372 PASQLPSGSPSVSSLPAKP-RPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPP------P 2424
Query: 779 PGLAPARSPGP 789
P L P SP P
Sbjct: 2425 PPLPPPTSPKP 2435
Score = 35.0 bits (79), Expect = 0.35
Identities = 14/23 (60%), Positives = 14/23 (60%)
Query: 40 PEAPSPPSADVNSPPPLPPPTSP 62
P P PP PPPLPPPTSP
Sbjct: 2411 PPPPPPPPPPPPPPPPLPPPTSP 2433
Score = 34.7 bits (78), Expect = 0.46
Identities = 20/68 (29%), Positives = 25/68 (36%), Gaps = 25/68 (36%)
Query: 704 YYCASRHDPPPRRPAAPPGPPGPAAPPAPSPAAPVRTRRRRKLYELHAAGAPPPPPPGHA 763
++ +S D + P PP PP P P PPPPPP
Sbjct: 2393 FFRSSSLDISAQPPPPPPPPPPPPPP-------------------------PPPPPPPPL 2427
Query: 764 PAPESPRP 771
P P SP+P
Sbjct: 2428 PPPTSPKP 2435
Score = 33.1 bits (74), Expect = 1.3
Identities = 32/137 (23%), Positives = 50/137 (36%), Gaps = 20/137 (14%)
Query: 16 LGDMEAREEVQLVGASHMEQKATAPEAPSPPSADVNSPPPLPPPTSP--------GGPKE 67
+ D EA +E ++++ PE P P P+P P G PK
Sbjct: 179 ISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKS 238
Query: 68 LEGQEPEPRPTEEE-PGSPWSGPDELE-------PVVQDGQRRIRARLSLATGLSWGPFH 119
+ Q+PE ++ G P GP + P+ +D R + + G S P
Sbjct: 239 ISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSL 298
Query: 120 GSVQTRASSPRQAEPSP 136
S S P +P+P
Sbjct: 299 PS----PSKPPIQQPTP 311
Score = 31.2 bits (69), Expect = 5.1
Identities = 27/94 (28%), Positives = 32/94 (34%), Gaps = 12/94 (12%)
Query: 882 GAPLAGPGVEARTPADRGPSPAPAPAASPQPGSRGPRDGLGPEPQEPPPGPPP------- 934
G P+ GP +T D P A+ PQ G +P P P PP
Sbjct: 255 GKPIQGPTQTPQT--DHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPG 312
Query: 935 -SPAAAP--EAVPPPPAPPSYSDKGVQTPSKGTP 965
PA P E P PA P G+ P P
Sbjct: 313 KPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQP 346
Score = 31.2 bits (69), Expect = 5.1
Identities = 18/52 (34%), Positives = 24/52 (46%), Gaps = 6/52 (11%)
Query: 37 ATAPEAPSP----PSADVNS--PPPLPPPTSPGGPKELEGQEPEPRPTEEEP 82
++ P P P S D+++ PPP PPP P P P P PT +P
Sbjct: 2384 SSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKP 2435
Score = 30.8 bits (68), Expect = 6.7
Identities = 34/124 (27%), Positives = 48/124 (38%), Gaps = 23/124 (18%)
Query: 401 SFQQQHTALQGPLASADLGLAPTPSPGLDRKALAEATNGEARAEPLAQNGGSSEPPAAPR 460
S QH L P + D SPG+D K LA E + L Q+
Sbjct: 4596 SENSQHLELHEPPKAVD----KAKSPGVDPKQLA----AELQKVSLQQS----------- 4636
Query: 461 SIKVEAVEEPEAAPILGPGEPGPQAPSRTPSPRSPAPARVKAELSSPTPG----SSPVPG 516
+ + +V E + GP G + P SP+ ++ K S PT G S P+ G
Sbjct: 4637 PLVLSSVVEKGSHVHSGPTSAGSSSVPSPGQPGSPSVSKKKHGSSKPTDGTKVVSHPITG 4696
Query: 517 ELGL 520
E+ L
Sbjct: 4697 EIQL 4700
Score = 30.4 bits (67), Expect = 8.7
Identities = 20/73 (27%), Positives = 28/73 (38%), Gaps = 11/73 (15%)
Query: 36 KATAPEAPSPPSADVNSPPP-LPPPTSPGGPKELEGQEPEP-------RPTEEEPGS--- 84
++ P PSP + P P PP PG K G P +P ++PG+
Sbjct: 292 ESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKP 351
Query: 85 PWSGPDELEPVVQ 97
P P +P Q
Sbjct: 352 PVQPPGTTKPPAQ 364
Score = 30.4 bits (67), Expect = 8.7
Identities = 13/33 (39%), Positives = 16/33 (48%)
Query: 30 ASHMEQKATAPEAPSPPSADVNSPPPLPPPTSP 62
+S ++ A P P PP PPP PPP P
Sbjct: 2396 SSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLP 2428
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 87.8 bits (216), Expect = 5e-17
Identities = 138/592 (23%), Positives = 191/592 (32%), Gaps = 113/592 (19%)
Query: 396 PDSLGSFQQQHTALQGPLASADLGLAPTPSPGLDRKALA---EATNGEARAEPLAQNGGS 452
P S+ S Q + Q P + PT +P D L +A+ + + + + G
Sbjct: 236 PKSISSQQPEKIKSQPPGTGKPIQ-GPTQTPQTDHAKLPLQRDASRPQTKQADIVR--GE 292
Query: 453 SEPPAAPRSIKVEAVEEPEAAPILGPGEPGPQAPSRTPSPRSPAPARVKAELSSPTPGSS 512
S P+ P K +++P PG+P Q P S P PA+ A+ S T +
Sbjct: 293 SVKPSLPSPSK-PPIQQPT------PGKPPAQQPGHEKS--QPGPAKPPAQPSGLTKPLA 343
Query: 513 PVPG----ELGLAGALFLPQYVFGPDAAPPASEILAKMSELVH---SRLQQGAGAGAGGA 565
PG + G P GP A PPA + ++ L Q G G A
Sbjct: 344 QQPGTVKPPVQPPGTTKPPAQPLGP-AKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPA 402
Query: 566 QTGLFPGAPKGATCFECEITFSNVNNYYVHKRLYCSGRRAPEDAPAARRPKAPPGPARAP 625
Q PG K T + P + P PGP + P
Sbjct: 403 QQ---PGPAKPPT-------------------QQVGTPKPLAQQPGLQSPAKAPGPTKTP 440
Query: 626 PGQPAEPDAPRSSPGPGAREEGAGGAATPEDGAGGRGSEGSQSPGSSVDDAEDDPSRTLC 685
QP P GPG G P G Q PG + + S
Sbjct: 441 VQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSA--- 497
Query: 686 EACNIRFSRHETYTVHKRYYCASRHDPPPRRPAAPPGPPGPAAPPAPSPAAPVRTRRRRK 745
PP ++P + PP P PSP P T+ +
Sbjct: 498 -------------------------KPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQ 532
Query: 746 LYELHAAGAPPPPPPGHAPAPESPRPGSGSGSGPGLAPARSPGPAADGPIDLSKKPRRPL 805
A + P P A +S +P S +GSG L P A P K PL
Sbjct: 533 -QPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPL 591
Query: 806 PGAP-----APALADYHECTACRVSFHSLEAYLAHKKYSCPAAPPPGALGLPAAACPYCP 860
P A+++ CT C+ + SL C P P + C C
Sbjct: 592 CNTTELLLHVPEKANFNTCTECQTTVCSL----------CGFNPNPHLTEVKEWLCLNCQ 641
Query: 861 PNGPVRGDLLEHFRLAHGLLLGAPLAGPGVEARTPADRGPSPAPAPAASPQPGSRGPRD- 919
+ GDL L AP+ T A SP P SP+ + +D
Sbjct: 642 MKRALGGDLAPVPSSPQPKLKTAPV------TTTSAVSKSSPQP-QQTSPKKDAAPKQDL 694
Query: 920 GLGPEPQEPPP----------------GPPPSPAAAPEAVPPPPAPPSYSDK 955
PEP++PPP PP + + + A P P+ PS DK
Sbjct: 695 SKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDK 746
Score = 65.1 bits (157), Expect = 3e-10
Identities = 80/301 (26%), Positives = 107/301 (35%), Gaps = 53/301 (17%)
Query: 712 PPPRRPAAPPGPPGPAAPPA-PS----PAA--------PVRTRRRRKLYELHAAGAPPPP 758
PP ++P PGPA PPA PS P A PV+ K A PP
Sbjct: 314 PPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPA 373
Query: 759 PPGHAPAPESPRPGS---GSGSGPGLAPARSPGPA------ADGPIDLSKKPRRPLPG-A 808
+ P S +PG G G PA+ PGPA P L+++P P A
Sbjct: 374 QQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKA 433
Query: 809 PAPALADYHECTACRVSFHSLEAYLAHKKYSCPAAPPPGALGLPAAACPYCPPNGPVRGD 868
P P + ++ + + P PP LP A P GP +
Sbjct: 434 PGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPS---QLPGPAKPPPQQPGPAKPP 490
Query: 869 LLEHFRLAHGLLLGAPLAGPGVEARTPADRGPS-PAPAPAASPQPGSRGPRDGLGPEPQE 927
+ P PG P GP+ P+P S +P S+ P P Q+
Sbjct: 491 PQQPGSAK------PPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQP-GSAKPSAQQ 543
Query: 928 PPPGPPPSPAAAPEAVPP--------PPAPPSYSDKGVQTPSKGTPAPLPNGNHRYCRLC 979
P P P +A ++ P P PP+ S Q PS+G P + C LC
Sbjct: 544 PSPAKP----SAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTI-------CPLC 592
Query: 980 N 980
N
Sbjct: 593 N 593
Score = 50.4 bits (119), Expect = 8e-06
Identities = 28/71 (39%), Positives = 35/71 (49%), Gaps = 4/71 (5%)
Query: 895 PADRGPSPAPAPA---ASPQPGSRGPRDGLGPEPQEPPPGPPPSPAAAPEAVPPPPAPPS 951
PA + PS +P+ + A P+P R + +P PPP PPP P P PPPP PP
Sbjct: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPP-PPPPPPPPPPPPPPPPLPPP 2430
Query: 952 YSDKGVQTPSK 962
S K P K
Sbjct: 2431 TSPKPTILPKK 2441
Score = 49.3 bits (116), Expect = 2e-05
Identities = 138/663 (20%), Positives = 198/663 (29%), Gaps = 124/663 (18%)
Query: 375 QPGSKGEIYSPGAGHPATKLPPDSLGSFQQ--------QHTALQGPLASADLGLAPTPSP 426
QPG K PG G + P + QQ Q LQ P + P P
Sbjct: 385 QPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQP 444
Query: 427 GLDRKALAEATNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILGPGEPGPQAP 486
G + +A G+ A+ Q G + P P K P P GP +P PQ P
Sbjct: 445 GPGKIPAQQAGPGKTSAQ---QTGPTKPPSQLPGPAK-----PPPQQP--GPAKPPPQQP 494
Query: 487 -----------SRTPSPRSPAPARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGPDA 535
S P P+ P PA+ + T S PG + P +
Sbjct: 495 GSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQS 554
Query: 536 APPASEI---LAKMSELVHSRLQQGAGAGAGGA------QTGLFPGAPKGA---TCFECE 583
P S+ V +Q G T L P+ A TC EC+
Sbjct: 555 TKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQ 614
Query: 584 ITFSNVNNYYVHKR---------LYCSGRRA----PEDAPAARRPKAPPGPARAPPGQPA 630
T ++ + + L C +RA P++ +PK P
Sbjct: 615 TTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSA--- 671
Query: 631 EPDAPRSSPGPGAREEGAGGAATPEDGAGGRGSEGSQSPGSSVDDAEDDPSRTLCEACNI 690
+SSP P ++ A P+ P PS
Sbjct: 672 ---VSKSSPQP--QQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPS--------- 717
Query: 691 RFSRHETYTVHKRYYCASRHDPPPRRPAAPPGPPGPAAPPAPSPAAPVRTRRRRK----- 745
A PP + P PP + P+ APV + ++
Sbjct: 718 ----------------AKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVK 761
Query: 746 ----LYELHAAGAPPPPPPG--HAPAPESPRPGSGSGSGPGLAPARSPGPAAD--GPIDL 797
L +A P P + A E P + S P++S P + P D
Sbjct: 762 PTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSA---KPSQSFPPTGEKVSPFD- 817
Query: 798 SKKPRRPLPGAPAPALADYHECTACRVSFHSLEAYLAHKKYSCPAAPPPGALGLPAAACP 857
SK RP + + + + ++ KK +P P A +P + P
Sbjct: 818 SKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGS-P 876
Query: 858 YCPPNGPVRGDLL-------------EHFRLAHGLLLGAPLAGPGVEARTPADR--GPSP 902
P P G + F L G + AP + P T + G
Sbjct: 877 TPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGA 936
Query: 903 APAPAASPQPGSRGPRDGLGPEPQEPPPGPPPSPAAAPEAVPPPPAPPSYSDKGVQTPSK 962
+ AS + G GP Q PG P A AP P PP + + P+K
Sbjct: 937 SIFSQASNLISTAGQP---GPHSQS-GPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAK 992
Query: 963 GTP 965
P
Sbjct: 993 SIP 995
Score = 46.2 bits (108), Expect = 2e-04
Identities = 74/333 (22%), Positives = 109/333 (32%), Gaps = 67/333 (20%)
Query: 446 LAQNGGSSEPPAAPRSIKVEAVEEPEAAPI-LGPGEPGPQAPSRTPSPRSPAPARVKAEL 504
++ G SSE + V+ EEP+ A + P P +P+P P P A
Sbjct: 831 ISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPT---AGQ 887
Query: 505 SSPTPGSSPVPGELGLAGALFLPQYVFGPDAAP--PASEILAKMSELVHSRLQQGAG--- 559
+ PTP SP P E +L L P + P P + K+ S Q +
Sbjct: 888 TVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLIS 947
Query: 560 -AGAGGAQTGLFPGAPKGATCFECEITFSNVNNYYVHKRLYCSGRRAPEDAPAARRPKAP 618
AG G + PGAP K+ + P +AP
Sbjct: 948 TAGQPGPHSQSGPGAPM--------------------KQAPAPSQPPTSQGPPKSTGQAP 987
Query: 619 PGPA---------RAPPGQPAEPDAPR--------SSPGPGAREEGAGGAATPEDGAGGR 661
P PA +AP + EP A + + P ++ A P+
Sbjct: 988 PAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPT 1047
Query: 662 GSEGSQSPGSSVD--------DAEDDPSRTLC-----EACNI-RFSRHETYTVHKRYYCA 707
E S P S+ ++D P+ C + CN+ F+ T + + C
Sbjct: 1048 KLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCL 1107
Query: 708 SRHDPPPRR------PAAPPGPPGPAAPPAPSP 734
+ PP P GP A P P P
Sbjct: 1108 NCQTQRAISGQLGDIRKMPPAPSGPKASPMPVP 1140
Score = 40.0 bits (92), Expect = 0.011
Identities = 192/936 (20%), Positives = 285/936 (30%), Gaps = 208/936 (22%)
Query: 21 AREEVQLVGASHMEQKATAPEAPSPP----SADVNSPPPLPPPTSPGGPKELEGQEPEPR 76
A+ Q G+ + P+A + P P P PPT G P+
Sbjct: 369 AKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVG---------TPK 419
Query: 77 PTEEEPG--SPWSGPDELE-PVVQDGQRRIRARLSLATGLSWGPFHGSV-QTRASSPRQA 132
P ++PG SP P + PV Q G +I A+ + GP S QT + P
Sbjct: 420 PLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQA-------GPGKTSAQQTGPTKPPSQ 472
Query: 133 EPSPALTLLLVDEACWLRTLPQALTEAEANTEIHRKDDALWCRVTKPVPAGGLLSVLLTA 192
P PA + PQ A KP P + +
Sbjct: 473 LPGPA------------KPPPQQPGPA------------------KPPPQQPGSAKPPSQ 502
Query: 193 EPHSTPGHPVKKEPAEPTCPAPAHDLQLLPQQAGMASILATAVINKDVFPCKDCGIWYRS 252
+P ST P + PA+P+ P + QQ G A A + P K
Sbjct: 503 QPGSTKPPPQQPGPAKPS-PQQPGSTKPPSQQPGSAKPSA-----QQPSPAKP------- 549
Query: 253 ERNLQAHLLYYCASRQGTGSPAAAATDEKPKETYPNERVCPFPQCRKSCPSASSLEIHMR 312
A S+ G+G P T P P + P + CP ++ E+ +
Sbjct: 550 ----SAQQSTKPVSQTGSGKPLQPPT-VSPSAKQPPSQGLP----KTICPLCNTTELLL- 599
Query: 313 SHSGERPFVCLICLSAFTTKANCERHLKVHTDTLSGVCHSCGFISTTRDILYSHLVTNHM 372
H E+ + F T C+ + VC CGF + +
Sbjct: 600 -HVPEK--------ANFNTCTECQ----------TTVCSLCGFNPNPHLTEVKEWLCLNC 640
Query: 373 VCQPGSKGEIYS-PGAGHPATKLPP------DSLGSFQQQHTALQGPLA-SADLGLAPTP 424
+ G++ P + P K P S S Q Q T+ + A DL AP P
Sbjct: 641 QMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEP 700
Query: 425 S---PGLDRKALAEATNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILGPGEP 481
P + + L + + +A+ P A + PP P E + AP+
Sbjct: 701 KKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEP-----SVPSEQDKAPVADDKPK 755
Query: 482 GPQAPSRTPSPRSPAPARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGPDAAPPASE 541
P+ T S + A K ++ S S A P D+A P S+
Sbjct: 756 QPKMVKPTTDLVSSSSATTKPDIPSSKVQSQ--------AEEKTTPP--LKTDSAKP-SQ 804
Query: 542 ILAKMSELVHSRLQQGAGAGAGGAQTGLFPGAPKGATCFECEITFSNVNNYYVHKRLYCS 601
E V + A ++ PG P + + ++ V K+
Sbjct: 805 SFPPTGEKVSPFDSKAIPRPASDSKIISHPG-PSSESKGQKQV--DPVQKKEEPKKAQTK 861
Query: 602 GRRAPEDAPAARRPKAPPGPARAPPGQPAEPDAPRSSPGPGAREEGAGGAATPEDGAGGR 661
P+ P + PPGP R GQ P+ SP P +
Sbjct: 862 MSPKPDAKPMPKGSPTPPGP-RPTAGQTV--PTPQQSPKPQEQSR--------------- 903
Query: 662 GSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPR------ 715
S + GS D + P+ F + ++ P P
Sbjct: 904 --RFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPG 961
Query: 716 -------RPAAPPGPPGP-----AAPPAPSPAAPVRTRRRRKLYELHAAGAPPPPPPGHA 763
P+ PP GP APPAP+ + PV+ + E A P
Sbjct: 962 APMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRT 1021
Query: 764 PAPESPRPGSGSGSGPGLAPARSPGPAADGPIDLSKKPRRPLP--------GAPAPALAD 815
+ P P S S A ++ S KP P G+ P +
Sbjct: 1022 ETEKKPPPIKDSKS----LTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDP--PN 1075
Query: 816 YHECTACRVSFHSLEAYLAHKKYSCPAAPPPGALGLPAAACPYCPPNGPVRGDLLEHFRL 875
++ CT C+ +L C P P + C C + G L +
Sbjct: 1076 FNTCTECKNQVCNL----------CGFNPTPHLTEIQEWLCLNCQTQRAISGQLGD---- 1121
Query: 876 AHGLLLGAPLAGPGVEARTPADRGP--SPAPAPAAS 909
+ PA GP SP P P S
Sbjct: 1122 --------------IRKMPPAPSGPKASPMPVPTES 1143
Score = 38.9 bits (89), Expect = 0.025
Identities = 36/121 (29%), Positives = 42/121 (34%), Gaps = 34/121 (28%)
Query: 712 PPPRRPAAPPGPPGPAAPPAPSPAAPVRTRRRRK-------------LYE---------- 748
PPP P PP PP P PP P P +P T +K L++
Sbjct: 2408 PPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAV 2467
Query: 749 LHAAGAPPPPPPGHAPAPESPRPGSGSGSGPGLAPARSPGPAADGPIDLSKKPRRPLPGA 808
L + G P AP P P+P S GL P P SK P P P
Sbjct: 2468 LRSNGLPVTRICTTAPPPVPPKP---SSIPSGLVFTHRPEP--------SKPPIAPKPVI 2516
Query: 809 P 809
P
Sbjct: 2517 P 2517
Score = 36.2 bits (82), Expect = 0.16
Identities = 26/71 (36%), Positives = 30/71 (42%), Gaps = 9/71 (12%)
Query: 721 PGPPGPAAPPAPS--PAAPVRTRRRRKLYELHAAGAPPPPPPGHAPAPESPRPGSGSGSG 778
P P+ P+ S PA P R R ++ A PPPPPP P P P P
Sbjct: 2372 PASQLPSGSPSVSSLPAKP-RPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPP------P 2424
Query: 779 PGLAPARSPGP 789
P L P SP P
Sbjct: 2425 PPLPPPTSPKP 2435
Score = 35.0 bits (79), Expect = 0.35
Identities = 14/23 (60%), Positives = 14/23 (60%)
Query: 40 PEAPSPPSADVNSPPPLPPPTSP 62
P P PP PPPLPPPTSP
Sbjct: 2411 PPPPPPPPPPPPPPPPLPPPTSP 2433
Score = 34.7 bits (78), Expect = 0.46
Identities = 20/68 (29%), Positives = 25/68 (36%), Gaps = 25/68 (36%)
Query: 704 YYCASRHDPPPRRPAAPPGPPGPAAPPAPSPAAPVRTRRRRKLYELHAAGAPPPPPPGHA 763
++ +S D + P PP PP P P PPPPPP
Sbjct: 2393 FFRSSSLDISAQPPPPPPPPPPPPPP-------------------------PPPPPPPPL 2427
Query: 764 PAPESPRP 771
P P SP+P
Sbjct: 2428 PPPTSPKP 2435
Score = 33.1 bits (74), Expect = 1.3
Identities = 32/137 (23%), Positives = 50/137 (36%), Gaps = 20/137 (14%)
Query: 16 LGDMEAREEVQLVGASHMEQKATAPEAPSPPSADVNSPPPLPPPTSP--------GGPKE 67
+ D EA +E ++++ PE P P P+P P G PK
Sbjct: 179 ISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKS 238
Query: 68 LEGQEPEPRPTEEE-PGSPWSGPDELE-------PVVQDGQRRIRARLSLATGLSWGPFH 119
+ Q+PE ++ G P GP + P+ +D R + + G S P
Sbjct: 239 ISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSL 298
Query: 120 GSVQTRASSPRQAEPSP 136
S S P +P+P
Sbjct: 299 PS----PSKPPIQQPTP 311
Score = 31.2 bits (69), Expect = 5.1
Identities = 27/94 (28%), Positives = 32/94 (34%), Gaps = 12/94 (12%)
Query: 882 GAPLAGPGVEARTPADRGPSPAPAPAASPQPGSRGPRDGLGPEPQEPPPGPPP------- 934
G P+ GP +T D P A+ PQ G +P P P PP
Sbjct: 255 GKPIQGPTQTPQT--DHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPG 312
Query: 935 -SPAAAP--EAVPPPPAPPSYSDKGVQTPSKGTP 965
PA P E P PA P G+ P P
Sbjct: 313 KPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQP 346
Score = 31.2 bits (69), Expect = 5.1
Identities = 18/52 (34%), Positives = 24/52 (46%), Gaps = 6/52 (11%)
Query: 37 ATAPEAPSP----PSADVNS--PPPLPPPTSPGGPKELEGQEPEPRPTEEEP 82
++ P P P S D+++ PPP PPP P P P P PT +P
Sbjct: 2384 SSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKP 2435
Score = 30.8 bits (68), Expect = 6.7
Identities = 34/124 (27%), Positives = 48/124 (38%), Gaps = 23/124 (18%)
Query: 401 SFQQQHTALQGPLASADLGLAPTPSPGLDRKALAEATNGEARAEPLAQNGGSSEPPAAPR 460
S QH L P + D SPG+D K LA E + L Q+
Sbjct: 4596 SENSQHLELHEPPKAVD----KAKSPGVDPKQLA----AELQKVSLQQS----------- 4636
Query: 461 SIKVEAVEEPEAAPILGPGEPGPQAPSRTPSPRSPAPARVKAELSSPTPG----SSPVPG 516
+ + +V E + GP G + P SP+ ++ K S PT G S P+ G
Sbjct: 4637 PLVLSSVVEKGSHVHSGPTSAGSSSVPSPGQPGSPSVSKKKHGSSKPTDGTKVVSHPITG 4696
Query: 517 ELGL 520
E+ L
Sbjct: 4697 EIQL 4700
Score = 30.4 bits (67), Expect = 8.7
Identities = 20/73 (27%), Positives = 28/73 (38%), Gaps = 11/73 (15%)
Query: 36 KATAPEAPSPPSADVNSPPP-LPPPTSPGGPKELEGQEPEP-------RPTEEEPGS--- 84
++ P PSP + P P PP PG K G P +P ++PG+
Sbjct: 292 ESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKP 351
Query: 85 PWSGPDELEPVVQ 97
P P +P Q
Sbjct: 352 PVQPPGTTKPPAQ 364
Score = 30.4 bits (67), Expect = 8.7
Identities = 13/33 (39%), Positives = 16/33 (48%)
Query: 30 ASHMEQKATAPEAPSPPSADVNSPPPLPPPTSP 62
+S ++ A P P PP PPP PPP P
Sbjct: 2396 SSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLP 2428
>gi|210031154 zinc finger protein 541 [Homo sapiens]
Length = 1365
Score = 85.5 bits (210), Expect = 2e-16
Identities = 145/591 (24%), Positives = 201/591 (34%), Gaps = 114/591 (19%)
Query: 268 QGTGSPAAAATDEKPKETYPNERVCPFPQCRKSCPSASSLEIHMRSHSGERPFVCLICLS 327
+G + + +A K + + P + C K SASSL H +HS ER VC IC
Sbjct: 116 EGGRATSGSARKGKRQHSSPQNPLLDCSLCGKVFSSASSLSKHYLTHSQERKHVCKICSK 175
Query: 328 AFTTKANCERHLKVHTDTLSGVCHSCGFISTTRDI--LYSHLVTNHMVC-----QPGSKG 380
AF + + H+ H T VC G + D L H +H +C P +
Sbjct: 176 AFKRQDHLTGHMLTHQKTKPFVCIEQGCSKSYCDYRSLRRHYEVHHGLCILKEAPPEEEA 235
Query: 381 EIYSPGAGHPATKLPPDSLGSFQQQHTALQGPLAS---------ADLGLAPTPSPGLDRK 431
SP A A + PP SL S G L + + TPSPG
Sbjct: 236 CGDSPHAHESAGQPPPSSLRSLVPPEARSPGSLLPHRDLLRRIVSSIVHQKTPSPG-PAP 294
Query: 432 ALAEATNGEARAEPLAQNGGSSE-----PPAAPRSIKVEAVEEP-----EAAPILGPGEP 481
A A + G A P + GSS P AAP ++ E EEP E A +
Sbjct: 295 AGASDSEGRNTACPCPASSGSSSCTPAGPHAAPAALDTELPEEPCLPQKEPATDVFTAPN 354
Query: 482 GPQAPSRTPSPRSPAPARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGPDAAPPASE 541
A + P P P P + S T P G + LF Q V P ++ P+S
Sbjct: 355 SRAAENGAPDPPEPEPDTALLQARS-TAECWPEGGSVPACLPLFRGQTV--PASSQPSSH 411
Query: 542 ILAKMSELVHSRLQQGAGAGAGGAQTGLFPGAPKGATCFECEITFSNVNNYYVHKRLYCS 601
+ L PG PK N + VHK
Sbjct: 412 SFQWLRNL---------------------PGCPKS----------KGNNVFVVHK----- 435
Query: 602 GRRAPEDAPAARRPKAPPGPARAPPGQPAEPDAPRSSPGPGAREEGAGGAATPEDGAGGR 661
P P+ ++ PGP+ P + S PGPG E A P A R
Sbjct: 436 ----PSAVPSREGSESGPGPSSGSPSE-------ESPPGPGGGLED----ALPFPAALLR 480
Query: 662 -GSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRPAAP 720
+E P S+ EDDP C ++ + C + +P +
Sbjct: 481 VPAEAPSDPRSA--SGEDDP----CAPKKVKVDCDS-------FLCQNPGEPGLQEAQKA 527
Query: 721 PGPPGPAAPPAP----SPAAPVRTRRRRKLYEL------------HAAGAPPPPPPGHAP 764
G P A+P P+ + + +++++ AA + P P P
Sbjct: 528 GGLPADASPLFRQLFLKSQEPLVSHEQMQVFQMITKSQRIFSHAQVAAVSSQLPAPEGKP 587
Query: 765 APESPRPGSGSGSGPGLAPARSPGPAADGPIDLSKKP---RRPLPGAPAPA 812
A P G P LAPA A G + P R+ PG P A
Sbjct: 588 AALRPLQGPWPQQPPPLAPAVDSLHAGPGNPEAEGSPARRRKTTPGVPREA 638
Score = 38.1 bits (87), Expect = 0.042
Identities = 72/302 (23%), Positives = 93/302 (30%), Gaps = 55/302 (18%)
Query: 677 EDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRPAAPP-------GPPGPAA- 728
E S++ C+ ++R RH Y VH C + PP G P P++
Sbjct: 200 EQGCSKSYCDYRSLR--RH--YEVHHGL-CILKEAPPEEEACGDSPHAHESAGQPPPSSL 254
Query: 729 -----PPAPSPAA--PVRTRRRRKLYEL-HAAGAPPPPPPGHA----------PAPESPR 770
P A SP + P R RR + + H P P P A P P S
Sbjct: 255 RSLVPPEARSPGSLLPHRDLLRRIVSSIVHQKTPSPGPAPAGASDSEGRNTACPCPASSG 314
Query: 771 PGSGSGSGPGLAPARSPGPAADGPIDLSKKPRRPLPGAPAPALADYHECTACRVSFHSLE 830
S + +GP APA + P K+P + AP
Sbjct: 315 SSSCTPAGPHAAPAALDTELPEEPCLPQKEPATDVFTAP--------------------N 354
Query: 831 AYLAHKKYSCPAAPPPGALGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGPGV 890
+ A P P P L A + C P G L FR P +
Sbjct: 355 SRAAENGAPDPPEPEPDTALLQARSTAECWPEGGSVPACLPLFRGQTVPASSQPSSHSFQ 414
Query: 891 EART----PADRGPSPAPAPAASPQPGSRGPRDGLGPEPQEPPPGPPPSPAAAPEAVPPP 946
R P +G + S P G G GP P PP P E P
Sbjct: 415 WLRNLPGCPKSKGNNVFVVHKPSAVPSREGSESGPGPSSGSPSEESPPGPGGGLEDALPF 474
Query: 947 PA 948
PA
Sbjct: 475 PA 476
Score = 32.3 bits (72), Expect = 2.3
Identities = 34/115 (29%), Positives = 41/115 (35%), Gaps = 30/115 (26%)
Query: 844 PPPGALGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGPGVEARTPADRGPSPA 903
PPP +L PP G LL H L ++ V +TP+ P PA
Sbjct: 249 PPPSSLR------SLVPPEARSPGSLLPHRDLLRRIVSSI------VHQKTPS---PGPA 293
Query: 904 PAPA--------ASPQPGSRGPRDGLGPEPQEPPPGPPPSPAAAPEAVPPPPAPP 950
PA A A P P S G P GP +PAA +P P P
Sbjct: 294 PAGASDSEGRNTACPCPASSGSSSCT-------PAGPHAAPAALDTELPEEPCLP 341
Score = 30.4 bits (67), Expect = 8.7
Identities = 46/209 (22%), Positives = 72/209 (34%), Gaps = 24/209 (11%)
Query: 47 SADVNSPPPLPPPTSPGGPKELEGQEPE-PRPTEE-----EPGSPWSGPDELEPVVQDGQ 100
S+ V+ P P P +P G + EG+ P P P P + P L+ + +
Sbjct: 280 SSIVHQKTPSPGP-APAGASDSEGRNTACPCPASSGSSSCTPAGPHAAPAALDTELPE-- 336
Query: 101 RRIRARLSLATGLSWGPFHGSVQTRASSPRQAEPSPALTLLLVDEACWLR--TLPQALTE 158
+ AT + P + + A P + EP AL CW ++P L
Sbjct: 337 EPCLPQKEPATDVFTAPNSRAAENGAPDPPEPEPDTALLQARSTAECWPEGGSVPACLPL 396
Query: 159 AEANTEIHRKDDA----LWCRVTKPVPAGGLLSVLLTAEPHSTPGH--------PVKKEP 206
T + W R P +V + +P + P P P
Sbjct: 397 FRGQTVPASSQPSSHSFQWLRNLPGCPKSKGNNVFVVHKPSAVPSREGSESGPGPSSGSP 456
Query: 207 AEPTCPAPAHDLQ-LLPQQAGMASILATA 234
+E + P P L+ LP A + + A A
Sbjct: 457 SEESPPGPGGGLEDALPFPAALLRVPAEA 485
>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 1487
Score = 84.7 bits (208), Expect = 4e-16
Identities = 170/687 (24%), Positives = 205/687 (29%), Gaps = 180/687 (26%)
Query: 375 QPGSKGEIYSPGA----------GHPATKLPPDSLG-SFQQQHTALQGPLASADLGLAPT 423
+PG GE PGA G PP G + ++ GP L P
Sbjct: 613 EPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPG 672
Query: 424 PSPGLDRKALAEATNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILGPGEPGP 483
P PG K + GEA A L G P S + ++ P P G PG
Sbjct: 673 P-PGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLP----GTPGT 727
Query: 484 QAPSRTPSPRSPAPARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGPDAAPPASEIL 543
P P P A+ PG +PGE G AG + GP
Sbjct: 728 DGPKGASGPAGPPGAQ-------GPPGLQGMPGERGAAG-------IAGPKG-------- 765
Query: 544 AKMSELVHSRLQQGAGAGAGGAQTG-LFPGAPKGATCFECEITFSNVNNYYVHKRLYCSG 602
++ + G G TG + P P GA + E+ +G
Sbjct: 766 -DRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGP-----------AG 813
Query: 603 RRAPEDAPAARRPKAPPGPA--RAPPGQPAEPDA--------------------PRSSPG 640
AP R PPGPA PPG +P A P +PG
Sbjct: 814 SAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPG 873
Query: 641 P----------GAREEGAGGAATPEDGAGGR----GSEGSQSP-GSSVDDAEDDPSRTLC 685
P GAR AT GA GR GS G+ P G +D P
Sbjct: 874 PQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPK---- 929
Query: 686 EACNIRFSRHETYTVHKRYYCASRHDPPPRRPAAPPGPPGPAAPP-------------AP 732
+R D P A PG GPA PP A
Sbjct: 930 ---------------------GARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAE 968
Query: 733 SPAAPVRTRRRRKLYELHAA----GAPPPPPPGHAPAPESPRPGSGSGSGPG-------L 781
P P +R + L G P P P P + SG PG
Sbjct: 969 GPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLT 1028
Query: 782 APARSPG----PAADGPI----------DLSKKPRRPLPGAPAPALADYHECTACRVSFH 827
PA PG P ADGP D + PGAP P + +
Sbjct: 1029 GPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQG-- 1086
Query: 828 SLEAYLAHKKYSCPAAPPPGALGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAG 887
+ A P G G PA A P GP RGD E AG
Sbjct: 1087 --------DRGEAGAQGPMGPSG-PAGARGIQGPQGP-RGDKGE--------------AG 1122
Query: 888 PGVEARTPADRGPSPAPAPAASPQP-GSRGPRDGLGPEPQEPPPGPP-PSPAAAPEAVPP 945
E RG + P P G +G GP PPGP PS +P
Sbjct: 1123 EPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPG 1182
Query: 946 PPAPPSYSDKGVQTPSKGTPA-PLPNG 971
P PP + +T G P P P G
Sbjct: 1183 PIGPPGPRGRSGETGPAGPPGNPGPPG 1209
Score = 81.3 bits (199), Expect = 4e-15
Identities = 158/601 (26%), Positives = 193/601 (32%), Gaps = 139/601 (23%)
Query: 426 PGLDRKALAEATNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILG-PGEPGPQ 484
PG D A + GE LA G++ P P + P A + G PG+ GPQ
Sbjct: 518 PGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGL-----PGARGLTGRPGDAGPQ 572
Query: 485 -------APSRTPSPRSPAPARVKAELS-SPTPGSSPVPGELGLAGALFLPQYVFGPDAA 536
AP P P P + + PG GE G AG LP A
Sbjct: 573 GKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLP-------GA 625
Query: 537 PPASEILAKMSEL-----------VHSRLQQGA----------------GAGAGGAQTGL 569
P + K E R +QGA G G G+
Sbjct: 626 PGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGV 685
Query: 570 FPG--------APKGATCFECEITFSNVNNYYVHKRLYCSGRRAPEDAPAARRPKAPPGP 621
PG P+G F E G R P PK GP
Sbjct: 686 -PGEAGAPGLVGPRGERGFPGERGSPGAQGL--------QGPRGLPGTPGTDGPKGASGP 736
Query: 622 ARAPPGQPAEPDAPRSSPGPGAREEGAGGAATPEDGAGGRGSEGSQ-SPGSSVDDAEDDP 680
A PPG P + PG E GA G A P+ G G +G + +PG P
Sbjct: 737 A-GPPGAQGPPGL-QGMPG----ERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGP 790
Query: 681 SRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRPAAPPGPPGPAAPPAPSPAAPVRT 740
A + E +R P R PPGP G A PP + P
Sbjct: 791 IGPPGPA-GANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPG-ADGQPGAK 848
Query: 741 RRRRKLYELHAAGAPPPPPPGHAPAPESPRPGSGSGSGPGLAPARSPGPAADGPIDLSKK 800
+ + + AGAP P P AP P+ P +G G A+ P P A G
Sbjct: 849 GEQGEAGQKGDAGAPGPQGPSGAPGPQGP---TGVTGPKGARGAQGP-PGATG------- 897
Query: 801 PRRPLPGAPAPALADYHECTACRVSFHSLEAYLAHKKYSCPAAPPPGALGLPAAACPYCP 860
PGA A RV PPG+ G P P P
Sbjct: 898 ----FPGA------------AGRVG-------------------PPGSNGNPGPPGPPGP 922
Query: 861 --PNGP--VRGDLLEHFRLAHGLLLGAPLAGPGVEARTPADRGPSPAPAPAASPQ----- 911
+GP RGD R L G AGP E P D GPS A P PQ
Sbjct: 923 SGKDGPKGARGDSGPPGRAGEPGLQGP--AGPPGEKGEPGDDGPSGAEGP-PGPQGLAGQ 979
Query: 912 ------PGSRGPRDGLGPEPQEPPPGPPPSPAAAPEAVPP-PPAPPSYSDKGVQTPSKGT 964
PG RG R G PG +P A+ + PP P PP + + +G+
Sbjct: 980 RGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGS 1039
Query: 965 P 965
P
Sbjct: 1040 P 1040
Score = 74.7 bits (182), Expect = 4e-13
Identities = 163/639 (25%), Positives = 186/639 (29%), Gaps = 148/639 (23%)
Query: 426 PGLDRKALAEATNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILGPGEPGPQA 485
PGLD A EA + E + S P PR + E A G G
Sbjct: 293 PGLDG-AKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPG 351
Query: 486 PSRTPSPRSPAPARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGPDAAP--PASEIL 543
P+ P P PA PG+ GE G GA P+ GP P P S
Sbjct: 352 PAGPPGPVGPAG-------GPGFPGAPGAKGEAGPTGARG-PEGAQGPRGEPGTPGSPGP 403
Query: 544 AKMSELVHSRLQQGAGAGAG-----------------GAQTGLFPGAPKGATCFECEITF 586
A S + GA AG G Q P PKG T F
Sbjct: 404 AGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGF 463
Query: 587 SNVNNYYVHKRLYCSGRRAPEDAPAARRPKAPPGP--------ARAPPG--QPAEPDAPR 636
G + P+ P P+ PGP AR PG P P R
Sbjct: 464 --------------KGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGER 509
Query: 637 SSPGPGAREEGAGGAATPEDGAGGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHE 696
+PG G G A P+ G RG G P A DP R E
Sbjct: 510 GAPG-NRGFPGQDGLAGPKGAPGERGPSGLAGP----KGANGDPGRP-----------GE 553
Query: 697 TYTVHKRYYCASRHDPPPRRPAAP---------PGPPGPAAP---------PAPS----- 733
R D P+ P PGPPGP P P
Sbjct: 554 PGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGE 613
Query: 734 ---------PAAPVRTRRRRKLYELHAAGAPPPPPPG---------------HAPAPESP 769
P AP K E AAG P P P P P P
Sbjct: 614 PGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGP 673
Query: 770 RPGSGSGSGPGLAPARSPGPAADGPIDLSKKPRRPLPGAPAPALADYHECTACRVSFHSL 829
PG G G P + P GP + R PG A +
Sbjct: 674 -PGEGGKPGDQGVPGEAGAPGLVGP-----RGERGFPGERGSPGAQGLQGPR---GLPGT 724
Query: 830 EAYLAHKKYSCPAAP-----PPGALGLPA--AACPYCPPNGPVRGDLLEHFRLA-----H 877
K S PA P PPG G+P A P G RGD+ E
Sbjct: 725 PGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGD-RGDVGEKGPEGAPGKDG 783
Query: 878 GLLLGAPLAGPGVEARTPADRGPSPAPAPAASPQPGSRGPRDGLGPEPQEPPPGP----- 932
G L P+ PG A ++G P PA GS G R G + PPGP
Sbjct: 784 GRGLTGPIGPPG-PAGANGEKGEVGPPGPA-----GSAGARGAPGERGETGPPGPAGFAG 837
Query: 933 PPSPAAAPEAVPPPPAPPSYSDKGVQTPSKGTPAPLPNG 971
PP P A D G P + AP P G
Sbjct: 838 PPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQG 876
Score = 74.3 bits (181), Expect = 5e-13
Identities = 137/528 (25%), Positives = 166/528 (31%), Gaps = 140/528 (26%)
Query: 468 EEPEAAPILGP-GEPGPQAPSRTPSPRSPAPARVKAELSSPTP-GSSPVPGELGLAGALF 525
E + I+GP G PGPQ P+ PR K E +P P G PG G G
Sbjct: 108 EPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGD--KGEKGAPGPRGRDGEPGTPGNPGPPG 165
Query: 526 LPQYVFGPDAAPPASEILAKMSELVHSRLQQGAGAGAGGAQTGLFPGAPKGATCFECEIT 585
P GP P A +++ G AGGAQ G+ G P G
Sbjct: 166 PP----GPPGPPGLGGNFA-------AQMAGGFDEKAGGAQLGVMQG-PMGPM------- 206
Query: 586 FSNVNNYYVHKRLYCSGRRAPEDAPAARRPKAPPGPARAP--------PGQPAEPDA--- 634
P+ PPGPA AP PG+P EP
Sbjct: 207 ----------------------------GPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGP 238
Query: 635 --PRSSPGPGAREEGAGGAATPEDGAGGRGSEGSQS----PGS-------------SVDD 675
PR PGP + G A P AG RG G Q PG+ +D
Sbjct: 239 MGPRGPPGPPGKPGDDGEAGKPGK-AGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDG 297
Query: 676 AEDDPSRTLCEA-------------CNIRFSRHETYTVHKRYYCASRHDPPPRRPAAPPG 722
A+ + + R E +R + PA PPG
Sbjct: 298 AKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPG 357
Query: 723 PPGPA-------APPAPSPAAPVRTR----RRRKLYELHAAGAPPPPPPGHAPAPESPRP 771
P GPA AP A A P R + E G+P P P +
Sbjct: 358 PVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPG 417
Query: 772 GSGSGSGPGLAPARS-PGPAADGPIDLSKKPRRPLPGAPAPALADYHECTACRVSFHSLE 830
GS PG+A A PGP + P P P +A +
Sbjct: 418 AKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGF-------------- 463
Query: 831 AYLAHKKYSCPAAPPPGALGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGPGV 890
G G P A P P GP G+ E R A G G GP
Sbjct: 464 ------------KGEQGPKGEPGPAGPQGAP-GPA-GE--EGKRGARGEPGGVGPIGPPG 507
Query: 891 EARTPADRGPSPAPAPAASPQ--PGSRGPRDGLGPEPQEPPPGPPPSP 936
E P +RG P A P+ PG RGP GP+ PG P P
Sbjct: 508 ERGAPGNRG-FPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEP 554
Score = 72.8 bits (177), Expect = 2e-12
Identities = 127/512 (24%), Positives = 154/512 (30%), Gaps = 173/512 (33%)
Query: 377 GSKGEIYSPG-AGHPATKLPPDSLGSFQQQHTALQGPLASADLGLAPTPSPGLDRKALAE 435
G KGE+ PG AG + P G T GP A PG D + A+
Sbjct: 801 GEKGEVGPPGPAGSAGARGAPGERGE-----TGPPGPAGFAG-------PPGADGQPGAK 848
Query: 436 ATNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEPE----------------AAPILGP- 478
GEA + A G P AP V P+ AA +GP
Sbjct: 849 GEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPP 908
Query: 479 ------GEPGPQAPSRTPSPR-----SPAPARV-KAELSSPT--PGSSPVPGELGLAGAL 524
G PGP PS P+ S P R + L P PG PG+ G +GA
Sbjct: 909 GSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGA- 967
Query: 525 FLPQYVFGPDAAPPASEILAKMSELVHSRLQQGAGAGAGGAQTGLFPGAPKGATCFECEI 584
PP + LA +V Q+G FPG P
Sbjct: 968 ----------EGPPGPQGLAGQRGIVGLPGQRGERG---------FPGLPGP-------- 1000
Query: 585 TFSNVNNYYVHKRLYCSGRRAPEDAPAARRPKAPPGPARAP--------PGQPAEPDA-- 634
SG + AP A + PPGP P PG+ P A
Sbjct: 1001 ----------------SGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADG 1044
Query: 635 ---------------------------PRSSPGPGAR--------EEGAGGAATPEDGAG 659
P SPGP E GA G P AG
Sbjct: 1045 PPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAG 1104
Query: 660 GRGSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPP------ 713
RG +G Q P +A + R L H +T + PP
Sbjct: 1105 ARGIQGPQGPRGDKGEAGEPGERGL--------KGHRGFTGLQ-----GLPGPPGPSGDQ 1151
Query: 714 ----PRRPAAPPGPPGPAAPPA-------PSPAAPVRTRRRRKLYELHAAGAPPPPPPGH 762
P P+ P GPPGP P P P P R R + P PPG+
Sbjct: 1152 GASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGR-------SGETGPAGPPGN 1204
Query: 763 APAPESPRPGSGSGSGPGLAPARSPGPAADGP 794
P P P G G ++ GP GP
Sbjct: 1205 ---PGPPGPPGPPGPGIDMSAFAGLGPREKGP 1233
Score = 68.6 bits (166), Expect = 3e-11
Identities = 117/451 (25%), Positives = 142/451 (31%), Gaps = 97/451 (21%)
Query: 375 QPGSKGEIYSPG----AGHPATKLPPDSLGSFQQQHTALQGPLASADLGLAP--TPSPGL 428
QPG+KGE G AG P + P + G Q T + GP + P T PG
Sbjct: 844 QPGAKGEQGEAGQKGDAGAPGPQGPSGAPGP--QGPTGVTGPKGARGAQGPPGATGFPG- 900
Query: 429 DRKALAEATNGEARAEPLAQNGGSSEP-PAAPRSIKVEAVEEPEAAPILGPGEPGPQAPS 487
R P NG P P P ++ P GEPG Q P+
Sbjct: 901 ----------AAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPA 950
Query: 488 RTPSPRSPAPARVKAELSSPTPGSSPVPGELGLAG-----------ALFLPQYVFGPDAA 536
P + + P PG + G+ G+ G L P G A
Sbjct: 951 GPPGEKGEPGDDGPSGAEGP-PGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGA 1009
Query: 537 PPASEILAKMSELVHSRLQQGAGA-GAGGAQTGLFPGAPKGATCFECEITFSNVNNYYVH 595
P AS + L AG G G+ P GA + +
Sbjct: 1010 PGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGD------------ 1057
Query: 596 KRLYCSGRRAPEDAPAARRPKAPPGPARAPPGQPAEPDAPRSSPGPGAREEGAGGAATPE 655
G AP A P PGPA P G+ + E GA G P
Sbjct: 1058 -----RGETGAVGAPGAPGPPGSPGPA-GPTGKQGD-----------RGEAGAQGPMGPS 1100
Query: 656 DGAGGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPP-- 713
AG RG +G Q P +A + R L H +T PP
Sbjct: 1101 GPAGARGIQGPQGPRGDKGEAGEPGERGL--------KGHRGFT-----GLQGLPGPPGP 1147
Query: 714 --------PRRPAAPPGPPGPAAPPA-------PSPAAPVRTRRRRKLYELHAAGAPPPP 758
P P+ P GPPGP P P P P R R E AG P P
Sbjct: 1148 SGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSG--ETGPAGPPGNP 1205
Query: 759 PPGHAPAPESPRPGSGSGSGPGLAPARSPGP 789
P P P P PG + GL P R GP
Sbjct: 1206 GPPGPPGP--PGPGIDMSAFAGLGP-REKGP 1233
Score = 56.2 bits (134), Expect = 1e-07
Identities = 95/374 (25%), Positives = 117/374 (31%), Gaps = 95/374 (25%)
Query: 606 PEDAPAARRPKAPPGPARAPPGQPAEPDAPRSSPGPGAREEGAGGAATPEDGAGGRGSEG 665
P D A P G + PG + P+ PGP +G G P G +G +G
Sbjct: 90 PTDLATASGQPGPKGQ-KGEPGDIKDIVGPKGPPGP----QGPAGEQGPRGDRGDKGEKG 144
Query: 666 SQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRPAAPPGPPG 725
+ PG D E + +P P P PPGPPG
Sbjct: 145 A--PGPRGRDGEP----------------------------GTPGNPGPPGPPGPPGPPG 174
Query: 726 PAAPPAPSPAAPVRTRR-RRKLYELHAAGAP--PPPPPGHAPAPESPRPGSGSGSGPGLA 782
A A + +L + P P PPG A AP P+ G+ PG
Sbjct: 175 LGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAP-GPQGFQGNPGEPG-- 231
Query: 783 PARSPGPAADGPIDLSKKPRRPLPGAPAPALADYHECTACRVSFHSLEAYLAHKKYSCPA 842
P GP+ PR P PG P D A K
Sbjct: 232 -----EPGVSGPMG----PRGP-PGPPGKPGDDGE----------------AGKPGKAGE 265
Query: 843 APPPGALGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAP-LAGPGVEARTPADRGPS 901
PPG G A P P V+G G P L G EA P +G S
Sbjct: 266 RGPPGPQG--ARGFPGTPGLPGVKGH------------RGYPGLDGAKGEAGAPGVKGES 311
Query: 902 PAPAPAASPQP----------GSRGPRDGLGPEPQEPPPGP--PPSPAAAPEAVPPPPAP 949
+P SP P G GP G + PGP PP P P P P
Sbjct: 312 GSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGP-VGPAGGPGFPGA 370
Query: 950 PSYSDKGVQTPSKG 963
P + T ++G
Sbjct: 371 PGAKGEAGPTGARG 384
Score = 37.0 bits (84), Expect = 0.093
Identities = 28/106 (26%), Positives = 37/106 (34%), Gaps = 29/106 (27%)
Query: 856 CPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGPGVEARTPAD-------RGPSPAPAPAA 908
CP CP + L + GP + P D +GP PA
Sbjct: 86 CPICPTD----------------LATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAG 129
Query: 909 SPQP----GSRGPRDGLGPEPQEPPPGPPPSPAAAPEAVPPPPAPP 950
P G +G + GP ++ PG P +P P P PP PP
Sbjct: 130 EQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNP--GPPGPPGPPGPP 173
>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 1418
Score = 84.7 bits (208), Expect = 4e-16
Identities = 170/687 (24%), Positives = 205/687 (29%), Gaps = 180/687 (26%)
Query: 375 QPGSKGEIYSPGA----------GHPATKLPPDSLG-SFQQQHTALQGPLASADLGLAPT 423
+PG GE PGA G PP G + ++ GP L P
Sbjct: 544 EPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPG 603
Query: 424 PSPGLDRKALAEATNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILGPGEPGP 483
P PG K + GEA A L G P S + ++ P P G PG
Sbjct: 604 P-PGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLP----GTPGT 658
Query: 484 QAPSRTPSPRSPAPARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGPDAAPPASEIL 543
P P P A+ PG +PGE G AG + GP
Sbjct: 659 DGPKGASGPAGPPGAQ-------GPPGLQGMPGERGAAG-------IAGPKG-------- 696
Query: 544 AKMSELVHSRLQQGAGAGAGGAQTG-LFPGAPKGATCFECEITFSNVNNYYVHKRLYCSG 602
++ + G G TG + P P GA + E+ +G
Sbjct: 697 -DRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGP-----------AG 744
Query: 603 RRAPEDAPAARRPKAPPGPA--RAPPGQPAEPDA--------------------PRSSPG 640
AP R PPGPA PPG +P A P +PG
Sbjct: 745 SAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPG 804
Query: 641 P----------GAREEGAGGAATPEDGAGGR----GSEGSQSP-GSSVDDAEDDPSRTLC 685
P GAR AT GA GR GS G+ P G +D P
Sbjct: 805 PQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPK---- 860
Query: 686 EACNIRFSRHETYTVHKRYYCASRHDPPPRRPAAPPGPPGPAAPP-------------AP 732
+R D P A PG GPA PP A
Sbjct: 861 ---------------------GARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAE 899
Query: 733 SPAAPVRTRRRRKLYELHAA----GAPPPPPPGHAPAPESPRPGSGSGSGPG-------L 781
P P +R + L G P P P P + SG PG
Sbjct: 900 GPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLT 959
Query: 782 APARSPG----PAADGPI----------DLSKKPRRPLPGAPAPALADYHECTACRVSFH 827
PA PG P ADGP D + PGAP P + +
Sbjct: 960 GPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQG-- 1017
Query: 828 SLEAYLAHKKYSCPAAPPPGALGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAG 887
+ A P G G PA A P GP RGD E AG
Sbjct: 1018 --------DRGEAGAQGPMGPSG-PAGARGIQGPQGP-RGDKGE--------------AG 1053
Query: 888 PGVEARTPADRGPSPAPAPAASPQP-GSRGPRDGLGPEPQEPPPGPP-PSPAAAPEAVPP 945
E RG + P P G +G GP PPGP PS +P
Sbjct: 1054 EPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPG 1113
Query: 946 PPAPPSYSDKGVQTPSKGTPA-PLPNG 971
P PP + +T G P P P G
Sbjct: 1114 PIGPPGPRGRSGETGPAGPPGNPGPPG 1140
Score = 81.3 bits (199), Expect = 4e-15
Identities = 158/601 (26%), Positives = 193/601 (32%), Gaps = 139/601 (23%)
Query: 426 PGLDRKALAEATNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILG-PGEPGPQ 484
PG D A + GE LA G++ P P + P A + G PG+ GPQ
Sbjct: 449 PGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGL-----PGARGLTGRPGDAGPQ 503
Query: 485 -------APSRTPSPRSPAPARVKAELS-SPTPGSSPVPGELGLAGALFLPQYVFGPDAA 536
AP P P P + + PG GE G AG LP A
Sbjct: 504 GKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLP-------GA 556
Query: 537 PPASEILAKMSEL-----------VHSRLQQGA----------------GAGAGGAQTGL 569
P + K E R +QGA G G G+
Sbjct: 557 PGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGV 616
Query: 570 FPG--------APKGATCFECEITFSNVNNYYVHKRLYCSGRRAPEDAPAARRPKAPPGP 621
PG P+G F E G R P PK GP
Sbjct: 617 -PGEAGAPGLVGPRGERGFPGERGSPGAQGL--------QGPRGLPGTPGTDGPKGASGP 667
Query: 622 ARAPPGQPAEPDAPRSSPGPGAREEGAGGAATPEDGAGGRGSEGSQ-SPGSSVDDAEDDP 680
A PPG P + PG E GA G A P+ G G +G + +PG P
Sbjct: 668 A-GPPGAQGPPGL-QGMPG----ERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGP 721
Query: 681 SRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRPAAPPGPPGPAAPPAPSPAAPVRT 740
A + E +R P R PPGP G A PP + P
Sbjct: 722 IGPPGPA-GANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPG-ADGQPGAK 779
Query: 741 RRRRKLYELHAAGAPPPPPPGHAPAPESPRPGSGSGSGPGLAPARSPGPAADGPIDLSKK 800
+ + + AGAP P P AP P+ P +G G A+ P P A G
Sbjct: 780 GEQGEAGQKGDAGAPGPQGPSGAPGPQGP---TGVTGPKGARGAQGP-PGATG------- 828
Query: 801 PRRPLPGAPAPALADYHECTACRVSFHSLEAYLAHKKYSCPAAPPPGALGLPAAACPYCP 860
PGA A RV PPG+ G P P P
Sbjct: 829 ----FPGA------------AGRVG-------------------PPGSNGNPGPPGPPGP 853
Query: 861 --PNGP--VRGDLLEHFRLAHGLLLGAPLAGPGVEARTPADRGPSPAPAPAASPQ----- 911
+GP RGD R L G AGP E P D GPS A P PQ
Sbjct: 854 SGKDGPKGARGDSGPPGRAGEPGLQGP--AGPPGEKGEPGDDGPSGAEGP-PGPQGLAGQ 910
Query: 912 ------PGSRGPRDGLGPEPQEPPPGPPPSPAAAPEAVPP-PPAPPSYSDKGVQTPSKGT 964
PG RG R G PG +P A+ + PP P PP + + +G+
Sbjct: 911 RGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGS 970
Query: 965 P 965
P
Sbjct: 971 P 971
Score = 74.7 bits (182), Expect = 4e-13
Identities = 163/639 (25%), Positives = 186/639 (29%), Gaps = 148/639 (23%)
Query: 426 PGLDRKALAEATNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILGPGEPGPQA 485
PGLD A EA + E + S P PR + E A G G
Sbjct: 224 PGLDG-AKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPG 282
Query: 486 PSRTPSPRSPAPARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGPDAAP--PASEIL 543
P+ P P PA PG+ GE G GA P+ GP P P S
Sbjct: 283 PAGPPGPVGPAG-------GPGFPGAPGAKGEAGPTGARG-PEGAQGPRGEPGTPGSPGP 334
Query: 544 AKMSELVHSRLQQGAGAGAG-----------------GAQTGLFPGAPKGATCFECEITF 586
A S + GA AG G Q P PKG T F
Sbjct: 335 AGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGF 394
Query: 587 SNVNNYYVHKRLYCSGRRAPEDAPAARRPKAPPGP--------ARAPPG--QPAEPDAPR 636
G + P+ P P+ PGP AR PG P P R
Sbjct: 395 --------------KGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGER 440
Query: 637 SSPGPGAREEGAGGAATPEDGAGGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHE 696
+PG G G A P+ G RG G P A DP R E
Sbjct: 441 GAPG-NRGFPGQDGLAGPKGAPGERGPSGLAGP----KGANGDPGRP-----------GE 484
Query: 697 TYTVHKRYYCASRHDPPPRRPAAP---------PGPPGPAAP---------PAPS----- 733
R D P+ P PGPPGP P P
Sbjct: 485 PGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGE 544
Query: 734 ---------PAAPVRTRRRRKLYELHAAGAPPPPPPG---------------HAPAPESP 769
P AP K E AAG P P P P P P
Sbjct: 545 PGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGP 604
Query: 770 RPGSGSGSGPGLAPARSPGPAADGPIDLSKKPRRPLPGAPAPALADYHECTACRVSFHSL 829
PG G G P + P GP + R PG A +
Sbjct: 605 -PGEGGKPGDQGVPGEAGAPGLVGP-----RGERGFPGERGSPGAQGLQGPR---GLPGT 655
Query: 830 EAYLAHKKYSCPAAP-----PPGALGLPA--AACPYCPPNGPVRGDLLEHFRLA-----H 877
K S PA P PPG G+P A P G RGD+ E
Sbjct: 656 PGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGD-RGDVGEKGPEGAPGKDG 714
Query: 878 GLLLGAPLAGPGVEARTPADRGPSPAPAPAASPQPGSRGPRDGLGPEPQEPPPGP----- 932
G L P+ PG A ++G P PA GS G R G + PPGP
Sbjct: 715 GRGLTGPIGPPG-PAGANGEKGEVGPPGPA-----GSAGARGAPGERGETGPPGPAGFAG 768
Query: 933 PPSPAAAPEAVPPPPAPPSYSDKGVQTPSKGTPAPLPNG 971
PP P A D G P + AP P G
Sbjct: 769 PPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQG 807
Score = 74.3 bits (181), Expect = 5e-13
Identities = 137/528 (25%), Positives = 166/528 (31%), Gaps = 140/528 (26%)
Query: 468 EEPEAAPILGP-GEPGPQAPSRTPSPRSPAPARVKAELSSPTP-GSSPVPGELGLAGALF 525
E + I+GP G PGPQ P+ PR K E +P P G PG G G
Sbjct: 39 EPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGD--KGEKGAPGPRGRDGEPGTPGNPGPPG 96
Query: 526 LPQYVFGPDAAPPASEILAKMSELVHSRLQQGAGAGAGGAQTGLFPGAPKGATCFECEIT 585
P GP P A +++ G AGGAQ G+ G P G
Sbjct: 97 PP----GPPGPPGLGGNFA-------AQMAGGFDEKAGGAQLGVMQG-PMGPM------- 137
Query: 586 FSNVNNYYVHKRLYCSGRRAPEDAPAARRPKAPPGPARAP--------PGQPAEPDA--- 634
P+ PPGPA AP PG+P EP
Sbjct: 138 ----------------------------GPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGP 169
Query: 635 --PRSSPGPGAREEGAGGAATPEDGAGGRGSEGSQS----PGS-------------SVDD 675
PR PGP + G A P AG RG G Q PG+ +D
Sbjct: 170 MGPRGPPGPPGKPGDDGEAGKPGK-AGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDG 228
Query: 676 AEDDPSRTLCEA-------------CNIRFSRHETYTVHKRYYCASRHDPPPRRPAAPPG 722
A+ + + R E +R + PA PPG
Sbjct: 229 AKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPG 288
Query: 723 PPGPA-------APPAPSPAAPVRTR----RRRKLYELHAAGAPPPPPPGHAPAPESPRP 771
P GPA AP A A P R + E G+P P P +
Sbjct: 289 PVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPG 348
Query: 772 GSGSGSGPGLAPARS-PGPAADGPIDLSKKPRRPLPGAPAPALADYHECTACRVSFHSLE 830
GS PG+A A PGP + P P P +A +
Sbjct: 349 AKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGF-------------- 394
Query: 831 AYLAHKKYSCPAAPPPGALGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGPGV 890
G G P A P P GP G+ E R A G G GP
Sbjct: 395 ------------KGEQGPKGEPGPAGPQGAP-GPA-GE--EGKRGARGEPGGVGPIGPPG 438
Query: 891 EARTPADRGPSPAPAPAASPQ--PGSRGPRDGLGPEPQEPPPGPPPSP 936
E P +RG P A P+ PG RGP GP+ PG P P
Sbjct: 439 ERGAPGNRG-FPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEP 485
Score = 72.8 bits (177), Expect = 2e-12
Identities = 127/512 (24%), Positives = 154/512 (30%), Gaps = 173/512 (33%)
Query: 377 GSKGEIYSPG-AGHPATKLPPDSLGSFQQQHTALQGPLASADLGLAPTPSPGLDRKALAE 435
G KGE+ PG AG + P G T GP A PG D + A+
Sbjct: 732 GEKGEVGPPGPAGSAGARGAPGERGE-----TGPPGPAGFAG-------PPGADGQPGAK 779
Query: 436 ATNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEPE----------------AAPILGP- 478
GEA + A G P AP V P+ AA +GP
Sbjct: 780 GEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPP 839
Query: 479 ------GEPGPQAPSRTPSPR-----SPAPARV-KAELSSPT--PGSSPVPGELGLAGAL 524
G PGP PS P+ S P R + L P PG PG+ G +GA
Sbjct: 840 GSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGA- 898
Query: 525 FLPQYVFGPDAAPPASEILAKMSELVHSRLQQGAGAGAGGAQTGLFPGAPKGATCFECEI 584
PP + LA +V Q+G FPG P
Sbjct: 899 ----------EGPPGPQGLAGQRGIVGLPGQRGERG---------FPGLPGP-------- 931
Query: 585 TFSNVNNYYVHKRLYCSGRRAPEDAPAARRPKAPPGPARAP--------PGQPAEPDA-- 634
SG + AP A + PPGP P PG+ P A
Sbjct: 932 ----------------SGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADG 975
Query: 635 ---------------------------PRSSPGPGAR--------EEGAGGAATPEDGAG 659
P SPGP E GA G P AG
Sbjct: 976 PPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAG 1035
Query: 660 GRGSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPP------ 713
RG +G Q P +A + R L H +T + PP
Sbjct: 1036 ARGIQGPQGPRGDKGEAGEPGERGL--------KGHRGFTGLQ-----GLPGPPGPSGDQ 1082
Query: 714 ----PRRPAAPPGPPGPAAPPA-------PSPAAPVRTRRRRKLYELHAAGAPPPPPPGH 762
P P+ P GPPGP P P P P R R + P PPG+
Sbjct: 1083 GASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGR-------SGETGPAGPPGN 1135
Query: 763 APAPESPRPGSGSGSGPGLAPARSPGPAADGP 794
P P P G G ++ GP GP
Sbjct: 1136 ---PGPPGPPGPPGPGIDMSAFAGLGPREKGP 1164
Score = 68.6 bits (166), Expect = 3e-11
Identities = 117/451 (25%), Positives = 142/451 (31%), Gaps = 97/451 (21%)
Query: 375 QPGSKGEIYSPG----AGHPATKLPPDSLGSFQQQHTALQGPLASADLGLAP--TPSPGL 428
QPG+KGE G AG P + P + G Q T + GP + P T PG
Sbjct: 775 QPGAKGEQGEAGQKGDAGAPGPQGPSGAPGP--QGPTGVTGPKGARGAQGPPGATGFPG- 831
Query: 429 DRKALAEATNGEARAEPLAQNGGSSEP-PAAPRSIKVEAVEEPEAAPILGPGEPGPQAPS 487
R P NG P P P ++ P GEPG Q P+
Sbjct: 832 ----------AAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPA 881
Query: 488 RTPSPRSPAPARVKAELSSPTPGSSPVPGELGLAG-----------ALFLPQYVFGPDAA 536
P + + P PG + G+ G+ G L P G A
Sbjct: 882 GPPGEKGEPGDDGPSGAEGP-PGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGA 940
Query: 537 PPASEILAKMSELVHSRLQQGAGA-GAGGAQTGLFPGAPKGATCFECEITFSNVNNYYVH 595
P AS + L AG G G+ P GA + +
Sbjct: 941 PGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGD------------ 988
Query: 596 KRLYCSGRRAPEDAPAARRPKAPPGPARAPPGQPAEPDAPRSSPGPGAREEGAGGAATPE 655
G AP A P PGPA P G+ + E GA G P
Sbjct: 989 -----RGETGAVGAPGAPGPPGSPGPA-GPTGKQGD-----------RGEAGAQGPMGPS 1031
Query: 656 DGAGGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPP-- 713
AG RG +G Q P +A + R L H +T PP
Sbjct: 1032 GPAGARGIQGPQGPRGDKGEAGEPGERGL--------KGHRGFT-----GLQGLPGPPGP 1078
Query: 714 --------PRRPAAPPGPPGPAAPPA-------PSPAAPVRTRRRRKLYELHAAGAPPPP 758
P P+ P GPPGP P P P P R R E AG P P
Sbjct: 1079 SGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSG--ETGPAGPPGNP 1136
Query: 759 PPGHAPAPESPRPGSGSGSGPGLAPARSPGP 789
P P P P PG + GL P R GP
Sbjct: 1137 GPPGPPGP--PGPGIDMSAFAGLGP-REKGP 1164
Score = 47.4 bits (111), Expect = 7e-05
Identities = 75/284 (26%), Positives = 89/284 (31%), Gaps = 54/284 (19%)
Query: 717 PAAPPGPPGPAAPPAPSPAAPVRTRRRRKLYELHAAGAP-------PPPPPGHAPAPESP 769
P PPGP GPA P R + GAP P PG+ P P
Sbjct: 49 PKGPPGPQGPAGEQGP----------RGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPP 98
Query: 770 RPGSGSGSGPGLAPARSPG---PAADGPIDLSKKPRRPL--PGAPAPALADYHECTACRV 824
P G G A + G A + + + P P+ G P PA A +
Sbjct: 99 GPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQ------ 152
Query: 825 SFHSLEAYLAHKKYSCPAAP--PPGALGLP-----AAACPYCPPNGPVRGDLLEHFRLAH 877
F S P P PPG G P A GP F
Sbjct: 153 GFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTP 212
Query: 878 GL-----LLGAP-LAGPGVEARTPADRGPSPAPAPAASPQP----------GSRGPRDGL 921
GL G P L G EA P +G S +P SP P G GP
Sbjct: 213 GLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAA 272
Query: 922 GPEPQEPPPGP--PPSPAAAPEAVPPPPAPPSYSDKGVQTPSKG 963
G + PGP PP P P P P P + T ++G
Sbjct: 273 GARGNDGQPGPAGPPGP-VGPAGGPGFPGAPGAKGEAGPTGARG 315
Score = 36.6 bits (83), Expect = 0.12
Identities = 26/92 (28%), Positives = 34/92 (36%), Gaps = 22/92 (23%)
Query: 879 LLLGAPLAGPGVEARTPADRGPSPAPA-------PAASPQP-------------GSRGPR 918
LL+ A L G + R P +G P P P P G +G +
Sbjct: 15 LLVAAVLRCQGQDVRQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEK 74
Query: 919 DGLGPEPQEPPPGPPPSPAAAPEAVPPPPAPP 950
GP ++ PG P +P P P PP PP
Sbjct: 75 GAPGPRGRDGEPGTPGNP--GPPGPPGPPGPP 104
>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
Length = 1120
Score = 82.4 bits (202), Expect = 2e-15
Identities = 138/545 (25%), Positives = 188/545 (34%), Gaps = 122/545 (22%)
Query: 431 KALAEATNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILGPGEPGPQAPSRTP 490
K LAE G + E L++ G P + +E +E E GP GP+ +
Sbjct: 535 KRLAELRRGLLQGEALSEGG--RRLAKGPELMAIEGLENGE-----GPATAGPRLLTFQG 587
Query: 491 SPRSPAPARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGPDAAPPASEILAKMSELV 550
S SP EL + G P P L LP P +P I A+
Sbjct: 588 SELSP-------ELQAAMAGGGPEP--------LPLP-----PARSPSQESIGARSRGSG 627
Query: 551 HSRLQQGAGAGAGGAQTGLFPGAPKGATCFE--CEITFSNVNNYYVHKRLYCSGRRAPED 608
HS+ Q G P+G C YV +Y P+
Sbjct: 628 HSQEQPAPQPSGGDPSPPQERNLPEGTERPPKLCSSLPGQGPPPYVF--MY------PQG 679
Query: 609 APAARRPKAPPGPARA------PPGQPAEPDAPR------SSPGPGAREEGAGGAATPED 656
+P++ P PPG A PP P +P P+ S PGP + G A P
Sbjct: 680 SPSSPAPGPPPGAPWAFSYLAGPPATPPDPPRPKRRSHSLSRPGP-TEGDAEGEAEGPVG 738
Query: 657 GAGGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRR 716
G + ++ PG S PS T A R +++ + R PPP+R
Sbjct: 739 STLGSYATLTRRPGRSAL-VRTSPSVTPTPARGT--PRSQSFALRARR--KGPPPPPPKR 793
Query: 717 PAAPPGPPGPAAPP---APSPAAPVRTRRRRKLYELHAAGAPPPPPPGHAPA-------- 765
++ GP P PP +P P RRR L E PP PP PA
Sbjct: 794 LSSVSGP-SPEPPPLDESPGPKEGATGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEP 852
Query: 766 -PESPRPGSGSGSGPGLAPARSPGPAADGPIDLSKKPRRPLPGAPAPALADYHECTACRV 824
PE P GS SG GL A +G + + ++P+ P P P +
Sbjct: 853 GPEGTPPSRGS-SGEGLPFAE------EGNLTIKQRPK---PAGPPPRETPVPP----GL 898
Query: 825 SFHSLEAYLAHKKYSCPAAPPPGALGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAP 884
F+ E+ ++ P C P++ LL
Sbjct: 899 DFNLTESDTVKRR-------------------PKCREREPLQTALLAF------------ 927
Query: 885 LAGPGVEARTPADRGPSPAPAPAASPQPGSRGPRDGLGPEPQEPPPGPPPSPAAAPEAVP 944
GV + TP P P+P P SP P S P+ PEP P P+P A A+
Sbjct: 928 ----GVASATPGPAAPLPSPTPGESP-PASSLPQ----PEPSSLPAQGVPTPLAPSPAMQ 978
Query: 945 PPPAP 949
PP P
Sbjct: 979 PPVPP 983
Score = 69.3 bits (168), Expect = 2e-11
Identities = 119/482 (24%), Positives = 150/482 (31%), Gaps = 78/482 (16%)
Query: 418 LGLAPTPSPGLDRKALAEATNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEP----EAA 473
L L P SP + +G ++ +P Q G P R++ E E P +
Sbjct: 606 LPLPPARSPSQESIGARSRGSGHSQEQPAPQPSGGDPSPPQERNLP-EGTERPPKLCSSL 664
Query: 474 PILGP---------GEPGPQAPSRTPS---------------PRSPAPARVKAELSSPTP 509
P GP G P AP P P P P R LS P P
Sbjct: 665 PGQGPPPYVFMYPQGSPSSPAPGPPPGAPWAFSYLAGPPATPPDPPRPKRRSHSLSRPGP 724
Query: 510 GSSPVPGELGLAGALFLPQYVFGPDAAPPASEILAKMSELVHSRLQQGAGAGAGGAQTGL 569
GE L Y P L + S V +G A
Sbjct: 725 TEGDAEGEAEGPVGSTLGSYA--TLTRRPGRSALVRTSPSVTPTPARGTPRSQSFALRAR 782
Query: 570 FPGAPKGATCFECEITFSNVNNYYVHKRLYCSGRRAPEDAPAARRP---KAPPGPAR--- 623
G P KRL +PE P P + GP R
Sbjct: 783 RKGPPPPPP-----------------KRLSSVSGPSPEPPPLDESPGPKEGATGPRRRTL 825
Query: 624 APPGQPAEPDAPRSSPGPGA--REEGAGGAATPED-GAGGRG----SEGSQSPGSSVDDA 676
+ P P+EP P + GP + EE G TP G+ G G EG+ + A
Sbjct: 826 SEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLTIKQRPKPA 885
Query: 677 EDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRPA-----APPGPPGPAAPPA 731
P T + F+ E+ TV +R C R A A PGP P P
Sbjct: 886 GPPPRETPVPP-GLDFNLTESDTVKRRPKCREREPLQTALLAFGVASATPGPAAPLPSPT 944
Query: 732 PSPAAPVRTRRRRKLYELHAAGAPPPPPPGHA---PAPESPRPGSGSGSGPGLAPARSPG 788
P + P + + + L A G P P P A P P P PG S + P
Sbjct: 945 PGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPGPGLESSAASRWNGETEP- 1003
Query: 789 PAADGPIDLSKKPRRPLPGAPAPALADYHECTACRVSFHSLEAYLAHKKYSCPAAPPPGA 848
PAA P L K +PGA CT S L L + P G
Sbjct: 1004 PAA--PAALLK-----VPGAGTAPKPVSVACTQLAFSGPKLAPRLGPRPVPPPRPESTGT 1056
Query: 849 LG 850
+G
Sbjct: 1057 VG 1058
Score = 55.8 bits (133), Expect = 2e-07
Identities = 105/425 (24%), Positives = 133/425 (31%), Gaps = 112/425 (26%)
Query: 620 GPARAPP------GQPAEPDAPRSSPGPGAREEGAGGAATPED---GAGGRGSEGSQ--- 667
GPA A P G P+ + G G A +P GA RGS SQ
Sbjct: 574 GPATAGPRLLTFQGSELSPELQAAMAGGGPEPLPLPPARSPSQESIGARSRGSGHSQEQP 633
Query: 668 SPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASR--HDPPPRRPAAPPGPPG 725
+P S D R L E T C+S PPP P G P
Sbjct: 634 APQPSGGDPSPPQERNLPEG-----------TERPPKLCSSLPGQGPPPYVFMYPQGSPS 682
Query: 726 PAAPPAPSPAAPVRTRRRRKLYELHAAGAPPPPPPGHAPAPESPRPGSGSGSGPGLAPAR 785
AP P P AP + PP PP P P+ S S S PG
Sbjct: 683 SPAP-GPPPGAP---------WAFSYLAGPPATPPD----PPRPKRRSHSLSRPGPTEGD 728
Query: 786 SPGPAADGPID--------LSKKPRRPLPGAPAPALADYHECTACRVSFHSLEAYLAHKK 837
+ G A +GP+ L+++P R +P++ T R + S +++ +
Sbjct: 729 AEGEA-EGPVGSTLGSYATLTRRPGRSALVRTSPSVTP----TPARGTPRS-QSFALRAR 782
Query: 838 YSCPAAPPPGALGLPAAACPYCPP----NGPVRGDLLEHFRLAHGLLLGAPLAGPGVEAR 893
P PPP L + P PP GP G R L P AGP
Sbjct: 783 RKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKEGATGPRRRT-----LSEP-AGPSEPPG 836
Query: 894 TPADRGPSP-----APAPAASPQPGSRGPRDGLG------------PEPQEPPPGPPPSP 936
PA GP+ P P +P P +GL P+P PPP P P
Sbjct: 837 PPAPAGPASDTEEEEPGPEGTP-PSRGSSGEGLPFAEEGNLTIKQRPKPAGPPPRETPVP 895
Query: 937 AA-------------------------------APEAVPPPPAPPSYSDKGVQTPSKGTP 965
A P P AP G P+ P
Sbjct: 896 PGLDFNLTESDTVKRRPKCREREPLQTALLAFGVASATPGPAAPLPSPTPGESPPASSLP 955
Query: 966 APLPN 970
P P+
Sbjct: 956 QPEPS 960
Score = 49.7 bits (117), Expect = 1e-05
Identities = 106/434 (24%), Positives = 142/434 (32%), Gaps = 103/434 (23%)
Query: 387 AGHPATKLPPDSLGSFQQQHTA-------------LQGPLASADLGLAPTPSPGLDRKAL 433
AG PAT PPD ++ H+ +GP+ S LG T + R AL
Sbjct: 700 AGPPAT--PPDPPRPKRRSHSLSRPGPTEGDAEGEAEGPVGST-LGSYATLTRRPGRSAL 756
Query: 434 AEA----TNGEARAEPLAQNGG-----SSEPPAAPRSIKVEAVEEPEAAPI---LGPGEP 481
T AR P +Q+ PP P+ + + PE P+ GP E
Sbjct: 757 VRTSPSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKEG 816
Query: 482 G----------PQAPSRTPSPRSPAPARVKAELSSPTPGSSPVPGELGLAGALFLPQYVF 531
P PS P P PAPA ++ PG P G +G
Sbjct: 817 ATGPRRRTLSEPAGPSEPPGP--PAPAGPASDTEEEEPGPEGTPPSRGSSG--------- 865
Query: 532 GPDAAPPASEILAKMSELVHSRLQQGAGAGAGGAQTGLFPGAPKGATCFECEITFSNVNN 591
+ P A E + Q+ AG +T + PG + F+ +
Sbjct: 866 --EGLPFAEEGNLTIK-------QRPKPAGPPPRETPVPPG-----------LDFNLTES 905
Query: 592 YYVHKRLYCSGRRAPEDAPAARRPKAPPGPARAPPGQPAEPDAPRSSPGPGAREEGAGGA 651
V +R C R + A A G A A PG P AP SP PG E +
Sbjct: 906 DTVKRRPKCREREPLQTALLAF------GVASATPG----PAAPLPSPTPG---ESPPAS 952
Query: 652 ATPEDGAGGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHD 711
+ P+ ++G +P P C + S + +
Sbjct: 953 SLPQPEPSSLPAQGVPTP--LAPSPAMQPPVPPCPGPGLESSAASRW---------NGET 1001
Query: 712 PPPRRPAAPPGPPGPAAPPAPSPAAPVRTRRRRKLYELHAAGAPPPPPPGHAPAPESPRP 771
PP PAA PG P P A +L +G P G P P PRP
Sbjct: 1002 EPPAAPAALLKVPGAGTAPKPVSVA---------CTQLAFSGPKLAPRLGPRPVP-PPRP 1051
Query: 772 GSGSGSGPGLAPAR 785
S GPG A R
Sbjct: 1052 ESTGTVGPGQAQQR 1065
Score = 33.9 bits (76), Expect = 0.79
Identities = 36/127 (28%), Positives = 49/127 (38%), Gaps = 25/127 (19%)
Query: 875 LAHGLLLGAPLA--------GPGVEARTPADRGPSPAPA-------PAASPQPGSRGPRD 919
L GLL G L+ GP + A + G PA A + P +
Sbjct: 540 LRRGLLQGEALSEGGRRLAKGPELMAIEGLENGEGPATAGPRLLTFQGSELSPELQAAMA 599
Query: 920 GLGPEPQEPPPGPPPSPAAAPEAVPPPPAPPSYS-DKGVQTPSKGTPAP-----LPNGNH 973
G GPEP PP PS E++ +S ++ PS G P+P LP G
Sbjct: 600 GGGPEPLPLPPARSPS----QESIGARSRGSGHSQEQPAPQPSGGDPSPPQERNLPEGTE 655
Query: 974 RYCRLCN 980
R +LC+
Sbjct: 656 RPPKLCS 662
Score = 32.3 bits (72), Expect = 2.3
Identities = 27/80 (33%), Positives = 31/80 (38%), Gaps = 11/80 (13%)
Query: 57 PPPTSPGGPKELEGQEPEPRPTEEEPGSPWSGPDELEPVVQDGQRRIRARLSLATGLSWG 116
PPP P + G PEP P +E PG P G G R R LS G S
Sbjct: 786 PPPPPPKRLSSVSGPSPEPPPLDESPG-PKEG--------ATGPR--RRTLSEPAGPSEP 834
Query: 117 PFHGSVQTRASSPRQAEPSP 136
P + AS + EP P
Sbjct: 835 PGPPAPAGPASDTEEEEPGP 854
Score = 32.3 bits (72), Expect = 2.3
Identities = 52/216 (24%), Positives = 73/216 (33%), Gaps = 41/216 (18%)
Query: 34 EQKATAPEAPSPPSADVNSPPPLPPPTSPGGP-KELEGQEPEPRPTEEEPGSPWSGPDEL 92
++ AT P + S PP PP +P GP + E +EP P T GS G
Sbjct: 814 KEGATGPRRRTLSEPAGPSEPPGPP--APAGPASDTEEEEPGPEGTPPSRGSSGEG---- 867
Query: 93 EPVVQDGQRRIRARLSLATGLSWGPFHGSVQTRASSPRQAEPSPALTLLLVDEACWLRTL 152
P ++G I+ R A GP PR+ P L L E+ ++
Sbjct: 868 LPFAEEGNLTIKQRPKPA-----GP----------PPRETPVPPGLDFNLT-ESDTVKRR 911
Query: 153 PQALTEAEANTEIHRKDDALWCRVTKPVPAGGLLSVLLTAEPHSTPGHPVKKEPAEPTCP 212
P+ T + A P PA L P TPG + P
Sbjct: 912 PKCREREPLQTALL----AFGVASATPGPAAPL--------PSPTPGE------SPPASS 953
Query: 213 APAHDLQLLPQQAGMASILATAVINKDVFPCKDCGI 248
P + LP Q + + + V PC G+
Sbjct: 954 LPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPGPGL 989
>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
Length = 1202
Score = 82.4 bits (202), Expect = 2e-15
Identities = 138/545 (25%), Positives = 188/545 (34%), Gaps = 122/545 (22%)
Query: 431 KALAEATNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILGPGEPGPQAPSRTP 490
K LAE G + E L++ G P + +E +E E GP GP+ +
Sbjct: 617 KRLAELRRGLLQGEALSEGG--RRLAKGPELMAIEGLENGE-----GPATAGPRLLTFQG 669
Query: 491 SPRSPAPARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGPDAAPPASEILAKMSELV 550
S SP EL + G P P L LP P +P I A+
Sbjct: 670 SELSP-------ELQAAMAGGGPEP--------LPLP-----PARSPSQESIGARSRGSG 709
Query: 551 HSRLQQGAGAGAGGAQTGLFPGAPKGATCFE--CEITFSNVNNYYVHKRLYCSGRRAPED 608
HS+ Q G P+G C YV +Y P+
Sbjct: 710 HSQEQPAPQPSGGDPSPPQERNLPEGTERPPKLCSSLPGQGPPPYVF--MY------PQG 761
Query: 609 APAARRPKAPPGPARA------PPGQPAEPDAPR------SSPGPGAREEGAGGAATPED 656
+P++ P PPG A PP P +P P+ S PGP + G A P
Sbjct: 762 SPSSPAPGPPPGAPWAFSYLAGPPATPPDPPRPKRRSHSLSRPGP-TEGDAEGEAEGPVG 820
Query: 657 GAGGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRR 716
G + ++ PG S PS T A R +++ + R PPP+R
Sbjct: 821 STLGSYATLTRRPGRSAL-VRTSPSVTPTPARGT--PRSQSFALRARR--KGPPPPPPKR 875
Query: 717 PAAPPGPPGPAAPP---APSPAAPVRTRRRRKLYELHAAGAPPPPPPGHAPA-------- 765
++ GP P PP +P P RRR L E PP PP PA
Sbjct: 876 LSSVSGP-SPEPPPLDESPGPKEGATGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEP 934
Query: 766 -PESPRPGSGSGSGPGLAPARSPGPAADGPIDLSKKPRRPLPGAPAPALADYHECTACRV 824
PE P GS SG GL A +G + + ++P+ P P P +
Sbjct: 935 GPEGTPPSRGS-SGEGLPFAE------EGNLTIKQRPK---PAGPPPRETPVPP----GL 980
Query: 825 SFHSLEAYLAHKKYSCPAAPPPGALGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAP 884
F+ E+ ++ P C P++ LL
Sbjct: 981 DFNLTESDTVKRR-------------------PKCREREPLQTALLAF------------ 1009
Query: 885 LAGPGVEARTPADRGPSPAPAPAASPQPGSRGPRDGLGPEPQEPPPGPPPSPAAAPEAVP 944
GV + TP P P+P P SP P S P+ PEP P P+P A A+
Sbjct: 1010 ----GVASATPGPAAPLPSPTPGESP-PASSLPQ----PEPSSLPAQGVPTPLAPSPAMQ 1060
Query: 945 PPPAP 949
PP P
Sbjct: 1061 PPVPP 1065
Score = 69.3 bits (168), Expect = 2e-11
Identities = 119/482 (24%), Positives = 150/482 (31%), Gaps = 78/482 (16%)
Query: 418 LGLAPTPSPGLDRKALAEATNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEP----EAA 473
L L P SP + +G ++ +P Q G P R++ E E P +
Sbjct: 688 LPLPPARSPSQESIGARSRGSGHSQEQPAPQPSGGDPSPPQERNLP-EGTERPPKLCSSL 746
Query: 474 PILGP---------GEPGPQAPSRTPS---------------PRSPAPARVKAELSSPTP 509
P GP G P AP P P P P R LS P P
Sbjct: 747 PGQGPPPYVFMYPQGSPSSPAPGPPPGAPWAFSYLAGPPATPPDPPRPKRRSHSLSRPGP 806
Query: 510 GSSPVPGELGLAGALFLPQYVFGPDAAPPASEILAKMSELVHSRLQQGAGAGAGGAQTGL 569
GE L Y P L + S V +G A
Sbjct: 807 TEGDAEGEAEGPVGSTLGSYA--TLTRRPGRSALVRTSPSVTPTPARGTPRSQSFALRAR 864
Query: 570 FPGAPKGATCFECEITFSNVNNYYVHKRLYCSGRRAPEDAPAARRP---KAPPGPAR--- 623
G P KRL +PE P P + GP R
Sbjct: 865 RKGPPPPPP-----------------KRLSSVSGPSPEPPPLDESPGPKEGATGPRRRTL 907
Query: 624 APPGQPAEPDAPRSSPGPGA--REEGAGGAATPED-GAGGRG----SEGSQSPGSSVDDA 676
+ P P+EP P + GP + EE G TP G+ G G EG+ + A
Sbjct: 908 SEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLTIKQRPKPA 967
Query: 677 EDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRPA-----APPGPPGPAAPPA 731
P T + F+ E+ TV +R C R A A PGP P P
Sbjct: 968 GPPPRETPVPP-GLDFNLTESDTVKRRPKCREREPLQTALLAFGVASATPGPAAPLPSPT 1026
Query: 732 PSPAAPVRTRRRRKLYELHAAGAPPPPPPGHA---PAPESPRPGSGSGSGPGLAPARSPG 788
P + P + + + L A G P P P A P P P PG S + P
Sbjct: 1027 PGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPGPGLESSAASRWNGETEP- 1085
Query: 789 PAADGPIDLSKKPRRPLPGAPAPALADYHECTACRVSFHSLEAYLAHKKYSCPAAPPPGA 848
PAA P L K +PGA CT S L L + P G
Sbjct: 1086 PAA--PAALLK-----VPGAGTAPKPVSVACTQLAFSGPKLAPRLGPRPVPPPRPESTGT 1138
Query: 849 LG 850
+G
Sbjct: 1139 VG 1140
Score = 55.8 bits (133), Expect = 2e-07
Identities = 105/425 (24%), Positives = 133/425 (31%), Gaps = 112/425 (26%)
Query: 620 GPARAPP------GQPAEPDAPRSSPGPGAREEGAGGAATPED---GAGGRGSEGSQ--- 667
GPA A P G P+ + G G A +P GA RGS SQ
Sbjct: 656 GPATAGPRLLTFQGSELSPELQAAMAGGGPEPLPLPPARSPSQESIGARSRGSGHSQEQP 715
Query: 668 SPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASR--HDPPPRRPAAPPGPPG 725
+P S D R L E T C+S PPP P G P
Sbjct: 716 APQPSGGDPSPPQERNLPEG-----------TERPPKLCSSLPGQGPPPYVFMYPQGSPS 764
Query: 726 PAAPPAPSPAAPVRTRRRRKLYELHAAGAPPPPPPGHAPAPESPRPGSGSGSGPGLAPAR 785
AP P P AP + PP PP P P+ S S S PG
Sbjct: 765 SPAP-GPPPGAP---------WAFSYLAGPPATPPD----PPRPKRRSHSLSRPGPTEGD 810
Query: 786 SPGPAADGPID--------LSKKPRRPLPGAPAPALADYHECTACRVSFHSLEAYLAHKK 837
+ G A +GP+ L+++P R +P++ T R + S +++ +
Sbjct: 811 AEGEA-EGPVGSTLGSYATLTRRPGRSALVRTSPSVTP----TPARGTPRS-QSFALRAR 864
Query: 838 YSCPAAPPPGALGLPAAACPYCPP----NGPVRGDLLEHFRLAHGLLLGAPLAGPGVEAR 893
P PPP L + P PP GP G R L P AGP
Sbjct: 865 RKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKEGATGPRRRT-----LSEP-AGPSEPPG 918
Query: 894 TPADRGPSP-----APAPAASPQPGSRGPRDGLG------------PEPQEPPPGPPPSP 936
PA GP+ P P +P P +GL P+P PPP P P
Sbjct: 919 PPAPAGPASDTEEEEPGPEGTP-PSRGSSGEGLPFAEEGNLTIKQRPKPAGPPPRETPVP 977
Query: 937 AA-------------------------------APEAVPPPPAPPSYSDKGVQTPSKGTP 965
A P P AP G P+ P
Sbjct: 978 PGLDFNLTESDTVKRRPKCREREPLQTALLAFGVASATPGPAAPLPSPTPGESPPASSLP 1037
Query: 966 APLPN 970
P P+
Sbjct: 1038 QPEPS 1042
Score = 49.7 bits (117), Expect = 1e-05
Identities = 106/434 (24%), Positives = 142/434 (32%), Gaps = 103/434 (23%)
Query: 387 AGHPATKLPPDSLGSFQQQHTA-------------LQGPLASADLGLAPTPSPGLDRKAL 433
AG PAT PPD ++ H+ +GP+ S LG T + R AL
Sbjct: 782 AGPPAT--PPDPPRPKRRSHSLSRPGPTEGDAEGEAEGPVGST-LGSYATLTRRPGRSAL 838
Query: 434 AEA----TNGEARAEPLAQNGG-----SSEPPAAPRSIKVEAVEEPEAAPI---LGPGEP 481
T AR P +Q+ PP P+ + + PE P+ GP E
Sbjct: 839 VRTSPSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKEG 898
Query: 482 G----------PQAPSRTPSPRSPAPARVKAELSSPTPGSSPVPGELGLAGALFLPQYVF 531
P PS P P PAPA ++ PG P G +G
Sbjct: 899 ATGPRRRTLSEPAGPSEPPGP--PAPAGPASDTEEEEPGPEGTPPSRGSSG--------- 947
Query: 532 GPDAAPPASEILAKMSELVHSRLQQGAGAGAGGAQTGLFPGAPKGATCFECEITFSNVNN 591
+ P A E + Q+ AG +T + PG + F+ +
Sbjct: 948 --EGLPFAEEGNLTIK-------QRPKPAGPPPRETPVPPG-----------LDFNLTES 987
Query: 592 YYVHKRLYCSGRRAPEDAPAARRPKAPPGPARAPPGQPAEPDAPRSSPGPGAREEGAGGA 651
V +R C R + A A G A A PG P AP SP PG E +
Sbjct: 988 DTVKRRPKCREREPLQTALLAF------GVASATPG----PAAPLPSPTPG---ESPPAS 1034
Query: 652 ATPEDGAGGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHD 711
+ P+ ++G +P P C + S + +
Sbjct: 1035 SLPQPEPSSLPAQGVPTP--LAPSPAMQPPVPPCPGPGLESSAASRW---------NGET 1083
Query: 712 PPPRRPAAPPGPPGPAAPPAPSPAAPVRTRRRRKLYELHAAGAPPPPPPGHAPAPESPRP 771
PP PAA PG P P A +L +G P G P P PRP
Sbjct: 1084 EPPAAPAALLKVPGAGTAPKPVSVA---------CTQLAFSGPKLAPRLGPRPVP-PPRP 1133
Query: 772 GSGSGSGPGLAPAR 785
S GPG A R
Sbjct: 1134 ESTGTVGPGQAQQR 1147
Score = 33.9 bits (76), Expect = 0.79
Identities = 36/127 (28%), Positives = 49/127 (38%), Gaps = 25/127 (19%)
Query: 875 LAHGLLLGAPLA--------GPGVEARTPADRGPSPAPA-------PAASPQPGSRGPRD 919
L GLL G L+ GP + A + G PA A + P +
Sbjct: 622 LRRGLLQGEALSEGGRRLAKGPELMAIEGLENGEGPATAGPRLLTFQGSELSPELQAAMA 681
Query: 920 GLGPEPQEPPPGPPPSPAAAPEAVPPPPAPPSYS-DKGVQTPSKGTPAP-----LPNGNH 973
G GPEP PP PS E++ +S ++ PS G P+P LP G
Sbjct: 682 GGGPEPLPLPPARSPS----QESIGARSRGSGHSQEQPAPQPSGGDPSPPQERNLPEGTE 737
Query: 974 RYCRLCN 980
R +LC+
Sbjct: 738 RPPKLCS 744
Score = 32.3 bits (72), Expect = 2.3
Identities = 27/80 (33%), Positives = 31/80 (38%), Gaps = 11/80 (13%)
Query: 57 PPPTSPGGPKELEGQEPEPRPTEEEPGSPWSGPDELEPVVQDGQRRIRARLSLATGLSWG 116
PPP P + G PEP P +E PG P G G R R LS G S
Sbjct: 868 PPPPPPKRLSSVSGPSPEPPPLDESPG-PKEG--------ATGPR--RRTLSEPAGPSEP 916
Query: 117 PFHGSVQTRASSPRQAEPSP 136
P + AS + EP P
Sbjct: 917 PGPPAPAGPASDTEEEEPGP 936
Score = 32.3 bits (72), Expect = 2.3
Identities = 52/216 (24%), Positives = 73/216 (33%), Gaps = 41/216 (18%)
Query: 34 EQKATAPEAPSPPSADVNSPPPLPPPTSPGGP-KELEGQEPEPRPTEEEPGSPWSGPDEL 92
++ AT P + S PP PP +P GP + E +EP P T GS G
Sbjct: 896 KEGATGPRRRTLSEPAGPSEPPGPP--APAGPASDTEEEEPGPEGTPPSRGSSGEG---- 949
Query: 93 EPVVQDGQRRIRARLSLATGLSWGPFHGSVQTRASSPRQAEPSPALTLLLVDEACWLRTL 152
P ++G I+ R A GP PR+ P L L E+ ++
Sbjct: 950 LPFAEEGNLTIKQRPKPA-----GP----------PPRETPVPPGLDFNLT-ESDTVKRR 993
Query: 153 PQALTEAEANTEIHRKDDALWCRVTKPVPAGGLLSVLLTAEPHSTPGHPVKKEPAEPTCP 212
P+ T + A P PA L P TPG + P
Sbjct: 994 PKCREREPLQTALL----AFGVASATPGPAAPL--------PSPTPGE------SPPASS 1035
Query: 213 APAHDLQLLPQQAGMASILATAVINKDVFPCKDCGI 248
P + LP Q + + + V PC G+
Sbjct: 1036 LPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPGPGL 1071
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 82.0 bits (201), Expect = 3e-15
Identities = 99/385 (25%), Positives = 132/385 (34%), Gaps = 59/385 (15%)
Query: 615 PKAPPGPARAPPGQPAEPDAPRSSPGPGAREEGAGGAATPEDGAGGRGSEGSQSPGSSVD 674
P PP P PP P P P P A G+ + R SQ G+
Sbjct: 626 PPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFK 685
Query: 675 DAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRPAAPPGP--------PGP 726
P+ + ++ +++ + + PPP P PP P P P
Sbjct: 686 P----PTPPVMQSQSVK---------PQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAP 732
Query: 727 AAPPAP---SPAAPVRTRRRRKLYELHAAGAPPPPPPGHAPAPES---------PRPGSG 774
AP P +P P++ + + + ++ A PPPPPP AP P P P S
Sbjct: 733 CAPSLPQFSAPPPPLKIHQVQHITQV-APPTPPPPPPIPAPLPPQAPPKPLVTIPAPTST 791
Query: 775 SGSGPGLAPARSPGPAADGPIDLSKKPRRPLPGAPAPALADYHECTACRVSFHSLEAYLA 834
P + A P P P P + P PA + V +L
Sbjct: 792 KTVAPVVTQAAPPTPTPPVP------PAKKQPAFPASYIPPSPPTPPVPVPPPTLP---- 841
Query: 835 HKKYSCPAAPPPGALG-----LPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGPG 889
K+ S A PPP L + A + PP P +E L AP + P
Sbjct: 842 -KQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTP---PAMESQPLKPVPANVAPQSPPA 897
Query: 890 VEARTPADRGPSPAPAPAASPQPGSRGPRDGLGPEPQEPPPGPPPSPAAAPEAVPPPPAP 949
V+A+ P P+P P P P L P P P P P P P A P P
Sbjct: 898 VKAKPKWQPSSIPVPSPDFPPPP----PESSLVFPPPPPSPVPAPPPPPPPTASPTPDKS 953
Query: 950 PSYSDKGVQTPSKG--TPAPLPNGN 972
S K +T S G P P P N
Sbjct: 954 GSPGKKTSKTSSPGGKKPPPTPQRN 978
Score = 54.3 bits (129), Expect = 6e-07
Identities = 117/540 (21%), Positives = 170/540 (31%), Gaps = 131/540 (24%)
Query: 438 NGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILGPGEPGPQAPSRTPSPRSPAP 497
+ +AR E + + S PP +P+ V + +P L P P P P P P P P
Sbjct: 590 SSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPP---PPPPPPPP 646
Query: 498 ARVKAELSSPTPGSSP-----------VPGELGLAGALFLPQYVFGPDAAPPASEILAKM 546
+ ++ S+P+ GS+ + +GALF P + +IL
Sbjct: 647 PPLPSQ-SAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPP 705
Query: 547 SELVHSRLQQGAGAGAGGAQTGLFPGAPKGATCFECEITFS-NVNNYYVHKRLYCSGRRA 605
+ +V G A L P A C FS +H+ + +
Sbjct: 706 NGVVPPPPPPPPPPTPGSAMAQLKP-----APCAPSLPQFSAPPPPLKIHQVQHITQVAP 760
Query: 606 PEDAPAARRPKAPPGPARAPPGQPAEPDAPRSSPGPGAREEGAGGAATPEDGAGGRGSEG 665
P P PP PA PP P +P +P A P
Sbjct: 761 PTP------PPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAP----------- 803
Query: 666 SQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRPAAPPGPP- 724
+P V A+ P+ + AS P P P P PP
Sbjct: 804 -PTPTPPVPPAKKQPA-----------------------FPASYIPPSPPTPPVPVPPPT 839
Query: 725 -----GPAAPPAPSPAAPVRTRRRRKLYELHAAGAPPPPPPGHAPAPESPRPGSGSGSGP 779
A P PSP +PV + + ++ + PPP PP P P P + + P
Sbjct: 840 LPKQQSFCAKPPPSPLSPVPS----VVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSP 895
Query: 780 GLAPARSPGPAADGPIDLSKKPRRPLPGAPAPALADYHECTACRVSFHSLEAYLAHKKYS 839
A+ + P+ P P P P S
Sbjct: 896 PAVKAKPKWQPSSIPV--------PSPDFPPP------------------------PPES 923
Query: 840 CPAAPPPGALGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGPGVE-ARTPADR 898
PPP +PA P P P PG + ++T +
Sbjct: 924 SLVFPPPPPSPVPAPPPPPPPTASPTPD----------------KSGSPGKKTSKTSSPG 967
Query: 899 GPSPAPAPAASPQPGSRGPRDGLGPEPQEPPPG------PPPSPAAAP--EAVPPPPAPP 950
G P P P + S + PEP+ P PP+ + +P E +PPP APP
Sbjct: 968 GKKPPPTPQRNSSIKSSSGAE--HPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPP 1025
Score = 53.1 bits (126), Expect = 1e-06
Identities = 29/78 (37%), Positives = 34/78 (43%), Gaps = 6/78 (7%)
Query: 891 EARTPADRGPSPAPAPAASPQPGSRGPRDGLGPEPQEPPPGPPPSPAAAPEAVPPPPAPP 950
+AR + P + P SPQP P P P PPP PPP P P PPPP P
Sbjct: 592 KARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPS 651
Query: 951 SYSDKGVQTPSKGTPAPL 968
PS G+ AP+
Sbjct: 652 Q------SAPSAGSAAPM 663
Score = 49.7 bits (117), Expect = 1e-05
Identities = 71/289 (24%), Positives = 89/289 (30%), Gaps = 92/289 (31%)
Query: 718 AAPPGPPGPAAPPAPSPAAPVRTRRRRKLYELHAAGAPPPPPPGHAPAPESPRPGSGSG- 776
A+ P PP P PP P P P PPPPPP P+ +P GS +
Sbjct: 621 ASQPSPPLPPPPPPPPPPPP-----------------PPPPPPPPLPSQSAPSAGSAAPM 663
Query: 777 ----------------SG-------PGLAPARSPGPAADGPIDLSKKPRRPLPGAPAPAL 813
SG P + ++S P P + P P P P P
Sbjct: 664 FVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGS 723
Query: 814 ADYHECTACRVSFHSLEAYLAHKKYSCPAAPPPGALGLPAAACPYCPPNGPVRGDLLEHF 873
A +A K P P A LP + P PP P++ ++H
Sbjct: 724 A------------------MAQLK------PAPCAPSLPQFSAP--PP--PLKIHQVQHI 755
Query: 874 RLAHGLLLGAPLAGPGVEARTPADRGPSPAPAPAASPQ------PGSRGPRDGLGPEPQE 927
+A P TP P PAP P +P P + Q
Sbjct: 756 ---------TQVAPP-----TPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQA 801
Query: 928 PPPGPPPSPAAAPEAVPPPPAPPSYSDKGVQTPSKGTPAPLPNGNHRYC 976
PP P P P A P P SY TP P P +C
Sbjct: 802 APPTPTPP---VPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFC 847
Score = 47.4 bits (111), Expect = 7e-05
Identities = 55/217 (25%), Positives = 77/217 (35%), Gaps = 38/217 (17%)
Query: 606 PEDAPAARRPKAPPGPARAPPGQPAEPDAPRSSPGPG---AREEGAGGAA---TPEDGAG 659
PE + P P PA PP P P S PG ++ GG TP+ +
Sbjct: 921 PESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSS 980
Query: 660 GRGSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRPAA 719
+ S G++ P +P R ++ +F T S+ PP PAA
Sbjct: 981 IKSSSGAEHP---------EPKRPSVDSLVSKF------TPPAESGSPSKETLPP--PAA 1023
Query: 720 PPGP----------PGPAAPPAPSPAAPVRTRRRR-KLYELHAAGA----PPPPPPGHAP 764
PP P PG S APV + R + + E + + PPPPP P
Sbjct: 1024 PPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELP 1083
Query: 765 APESPRPGSGSGSGPGLAPARSPGPAADGPIDLSKKP 801
P P SG+ +P P + + K P
Sbjct: 1084 LPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAP 1120
Score = 40.0 bits (92), Expect = 0.011
Identities = 39/150 (26%), Positives = 59/150 (39%), Gaps = 10/150 (6%)
Query: 375 QPGSKGEIYSPGAGHPATKLPPDSLGSFQQQHTALQGPLASADLGLAPTPS--PGLDRKA 432
QP P P +PP +L QQ A P L+P PS + +
Sbjct: 816 QPAFPASYIPPSPPTPPVPVPPPTLPK-QQSFCAKPPPSP-----LSPVPSVVKQIASQF 869
Query: 433 LAEATNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILGPGEPGPQAPSRTPSP 492
T ++PL + ++ P +P ++K + +P + P+ P P P S P
Sbjct: 870 PPPPTPPAMESQPL-KPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFP 928
Query: 493 RSPAPARVKAELSSPTPGSSPVPGELGLAG 522
P P+ V A P P +SP P + G G
Sbjct: 929 -PPPPSPVPAPPPPPPPTASPTPDKSGSPG 957
Score = 35.8 bits (81), Expect = 0.21
Identities = 21/68 (30%), Positives = 27/68 (39%), Gaps = 5/68 (7%)
Query: 22 REEVQLVGASHMEQKATAPEAPSPPSADVNSPPPLPPPTSPGGPKELEGQEPEPRPTEEE 81
R LV + K P S PS + PPP PPP P P P P P++
Sbjct: 600 RPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPP-----PPPPPLPSQSA 654
Query: 82 PGSPWSGP 89
P + + P
Sbjct: 655 PSAGSAAP 662
Score = 34.7 bits (78), Expect = 0.46
Identities = 20/65 (30%), Positives = 27/65 (41%), Gaps = 13/65 (20%)
Query: 43 PSPPSADVNSPPPLPPPTSPGGPKEL-------------EGQEPEPRPTEEEPGSPWSGP 89
P PP + V +PPP PPPT+ P + G++P P P SG
Sbjct: 928 PPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGA 987
Query: 90 DELEP 94
+ EP
Sbjct: 988 EHPEP 992
Score = 33.9 bits (76), Expect = 0.79
Identities = 13/31 (41%), Positives = 19/31 (61%)
Query: 33 MEQKATAPEAPSPPSADVNSPPPLPPPTSPG 63
M+ ++ P+ PP+ V PPP PPP +PG
Sbjct: 692 MQSQSVKPQILVPPNGVVPPPPPPPPPPTPG 722
Score = 33.1 bits (74), Expect = 1.3
Identities = 19/55 (34%), Positives = 22/55 (40%), Gaps = 3/55 (5%)
Query: 901 SPAP---APAASPQPGSRGPRDGLGPEPQEPPPGPPPSPAAAPEAVPPPPAPPSY 952
SP P P + QP P P P PPP PPP P + A A P +
Sbjct: 610 SPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMF 664
Score = 33.1 bits (74), Expect = 1.3
Identities = 44/203 (21%), Positives = 65/203 (32%), Gaps = 34/203 (16%)
Query: 32 HMEQKATAPEAPSPPSADVNSPPPLPPPTSPGGPKELEGQEPEPRPTEE-EPGSPWSGPD 90
H Q T P+PP PPP+P P P P + P P T+ P + P
Sbjct: 750 HQVQHITQVAPPTPPP-----PPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPP 804
Query: 91 ELEPVVQDGQRRIRARLSLATGLSWGPFHGSVQTRASSPRQAEPSPALTLLLVDEACW-- 148
P V +++ P + S P P P TL C
Sbjct: 805 TPTPPVPPAKKQ--------------PAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKP 850
Query: 149 ----LRTLPQALTEAEANTEIHRKDDALWCRVTKPVPAGGLLSVLLTAEPHSTPGHPVKK 204
L +P + + + A+ + KPVPA P S P K
Sbjct: 851 PPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPA--------NVAPQSPPAVKAKP 902
Query: 205 EPAEPTCPAPAHDLQLLPQQAGM 227
+ + P P+ D P ++ +
Sbjct: 903 KWQPSSIPVPSPDFPPPPPESSL 925
Score = 32.3 bits (72), Expect = 2.3
Identities = 27/108 (25%), Positives = 43/108 (39%), Gaps = 24/108 (22%)
Query: 422 PTPSPGLDRKALAEATNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILGPGEP 481
PT SP D+ + + + GG PP R+ +++ G P
Sbjct: 944 PTASPTPDKSG-----SPGKKTSKTSSPGGKKPPPTPQRNSSIKSSS--------GAEHP 990
Query: 482 GPQAPSR-------TPSPRSPAPARVKAELSSPTPGSSPVPGELGLAG 522
P+ PS TP S +P++ + P P + P PG+L L+G
Sbjct: 991 EPKRPSVDSLVSKFTPPAESGSPSKE----TLPPPAAPPKPGKLNLSG 1034
>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
Length = 1466
Score = 81.6 bits (200), Expect = 3e-15
Identities = 175/683 (25%), Positives = 206/683 (30%), Gaps = 187/683 (27%)
Query: 376 PGSKGEIYSPGAGHPATKLPPDSLGSFQQQHTALQGPLASADLG--LAPTPSPGLDRKAL 433
PG GE PG P + PP G T QGP G T PG
Sbjct: 590 PGKNGERGGPGG--PGPQGPPGKNGE-----TGPQGPPGPTGPGGDKGDTGPPGPQGLQG 642
Query: 434 AEATNGEARAEPLAQNGGSSEP--------PAAPRSIKVEAVEEPEAAPIL--------G 477
T G P +NG EP P AP P L G
Sbjct: 643 LPGTGG-----PPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGG 697
Query: 478 PGEPGPQAPSRTPSPRSPAPARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGPDAAP 537
G PGP+ P P A + TPG +PGE G G+ P+ G P
Sbjct: 698 AGPPGPEGGKGAAGPPGPPGA-------AGTPGLQGMPGERGGLGSPG-PKGDKGEPGGP 749
Query: 538 PASEILAKMSELVHSRLQQGAGAGAGGAQTGLFPGAPKGATCFECEITFSNVNNYYVHKR 597
A + K G G + P P G + E +
Sbjct: 750 GADGVPGK--------------DGPRGPTGPIGPPGPAGQPGDKGEGGAPGL-------- 787
Query: 598 LYCSGRRAPEDAPAARRPKAPPGPARAP--PGQPAEPDAPRSSPGPGAREEGAG-GAATP 654
G P +P R PPGPA P PGQ EP PG + EG G A P
Sbjct: 788 ---PGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGP 844
Query: 655 EDGAGGRGSEGSQ-------SPG----SSVDDAEDDPSRTLCEACNIRFSRHETYTVHKR 703
G+G G G Q SPG + A P
Sbjct: 845 PGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPP-------------------- 884
Query: 704 YYCASRHDPPPRRPAAPPG---PPGPAA-------------------------------P 729
S +P P P+ PG PPGPA P
Sbjct: 885 ---GSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPP 941
Query: 730 PAPSPAAPVRTRRRRKLYELHAAGAPPPPPPGHAPAP-----ESPRPGSGSGSG------ 778
AP P R L AG P P P +P P ES +PG+ SG
Sbjct: 942 GAPGPLGIAGITGARGL-----AGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPG 996
Query: 779 ----PGLA-----PARSPGPAADG-------PIDLSKKPRRPLPGAPAPALADYHECTAC 822
PGLA P R P +DG P + PGAP A H
Sbjct: 997 PQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPG---APGHPGPPG 1053
Query: 823 RVSFHSLEAYLAHKKYSCPAAPPPGALGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLG 882
V A + + A P GA G PA + P GP RGD E + G
Sbjct: 1054 PVG----PAGKSGDRGESGPAGPAGAPG-PAGSRGAPGPQGP-RGDKGETGERGAAGIKG 1107
Query: 883 APLAGPGVEARTPADRGPSPAPAPAASPQPGSRGPRDGLGPEPQEPPPGPPPSPAAAPEA 942
G A P PA A PG GPR +GP GPP +
Sbjct: 1108 ----HRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPS------GPPGKDGTSGH- 1156
Query: 943 VPPPPAPPSYSDKGVQTPSKGTP 965
P P PP + S+G+P
Sbjct: 1157 -PGPIGPPGPRGNRGERGSEGSP 1178
Score = 79.7 bits (195), Expect = 1e-14
Identities = 157/599 (26%), Positives = 186/599 (31%), Gaps = 217/599 (36%)
Query: 375 QPGSKGEIYSPGAGHPATKLPPDSLGSFQQQHTALQGPLASADLGLAPTPS--PGLDRKA 432
QPG KGE +PG P P S G + GP A AP + PG +
Sbjct: 775 QPGDKGEGGAPGL--PGIAGPRGSPGERGET-----GPPGPAGFPGAPGQNGEPGGKGER 827
Query: 433 LAEATNGEARAEPLAQNGGSSEP--PAAPRSIKVEAVEE--PEAAPILGP-GEPGPQAPS 487
A GE +A G S P P P+ +K E P AA G G PGP +
Sbjct: 828 GAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSN 887
Query: 488 RTPSPRSPAPARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGP--DAAPPASEILAK 545
P P P S +PG PG G GA P V GP DA P +
Sbjct: 888 GNPGPPGP----------SGSPGKDGPPGPAGNTGAPGSPG-VSGPKGDAGQPGEK---- 932
Query: 546 MSELVHSRLQQGAGAGAGGAQTGLFPGAPKGATCFECEITFSNVNNYYVHKRLYCSGRRA 605
G+ GAQ PGAP + + + +G R
Sbjct: 933 ---------------GSPGAQGP--PGAPG-------PLGIAGI-----------TGARG 957
Query: 606 PEDAPAARRPKAPPGPARAPPGQPAEPDA-----PRSSPGPGAREEGAGGAATPEDGAGG 660
P P+ PGP + G+ +P A R PGP AG A P G
Sbjct: 958 LAGPPGMPGPRGSPGP-QGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRD-GN 1015
Query: 661 RGSEG----SQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRR 716
GS+G SPG D E+ P
Sbjct: 1016 PGSDGLPGRDGSPGGKGDRGENGS---------------------------------PGA 1042
Query: 717 PAAP--PGPPGPAAPPAPS-------PAAPVRTRRRRKLYELHAAGAPPPPPPGHAPAPE 767
P AP PGPPGP P S PA P AGAP P AP P+
Sbjct: 1043 PGAPGHPGPPGPVGPAGKSGDRGESGPAGP--------------AGAPGPAGSRGAPGPQ 1088
Query: 768 SPRPGSGSGSGPGLAPARSPGPAADGPIDLSKKPRRPLPGAPAPALADYHECTACRVSFH 827
PR G G A K R PG P
Sbjct: 1089 GPRGDKGETGERGAAGI---------------KGHRGFPGNPG----------------- 1116
Query: 828 SLEAYLAHKKYSCPAAPPP----GALGLPAAACPYCP--PNGPVRGDLLEHFRLAHGLLL 881
P +P P GA+G P A P P P+GP
Sbjct: 1117 ------------APGSPGPAGQQGAIGSPGPAGPRGPVGPSGP----------------- 1147
Query: 882 GAPLAGPGVEARTPADRGPSPAPAPAASPQP-GSRGPR--DGLGPEPQEP-PPGPPPSP 936
P G S P P P P G+RG R +G P +P PPGPP +P
Sbjct: 1148 -------------PGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAP 1193
Score = 77.8 bits (190), Expect = 5e-14
Identities = 183/692 (26%), Positives = 222/692 (32%), Gaps = 167/692 (24%)
Query: 376 PGSKGEIYSPGAGHPA--TKLPPDSLGSFQQQHTALQGPLASADLGLAPTPSPGLDRKAL 433
PG G+ SPG+ P + P ++ Q+ + A GLA P P
Sbjct: 123 PGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGP------- 175
Query: 434 AEATNGEARAEPLAQNG--GSSEPPAAPRSIKVEAVEEPEAAPILGPGEPGPQAPSRTPS 491
A P G G+S P +P S + PGEPG PS P
Sbjct: 176 ---------AGPPGPPGPPGTSGHPGSPGSPGYQGP----------PGEPGQAGPSGPPG 216
Query: 492 PRSP----APARVKAELSSP-TPGSSPVPGELGLAGALFLPQY----------------- 529
P PA E P PG +PG G+ G +P +
Sbjct: 217 PPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKG 276
Query: 530 ------------VFGPDAAPPASEILAKMSELVHSRLQQGAGA----GAGGAQTGLFPGA 573
+ G + AP E L AGA GA G+ P
Sbjct: 277 ETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPG 336
Query: 574 PKGATCF--------ECEITFSNVNNYYVHKRLYCSGRRAPEDAPAARRPKAPPGPARAP 625
P G F E S +N +R G P+ A+ P PPG +P
Sbjct: 337 PPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQR----GEPGPQGHAGAQGPPGPPGINGSP 392
Query: 626 PGQ----PAE-PDAP-----RSSPGP-----------GAREEGAGGAATPEDGAGGRGSE 664
G+ PA P AP R PGP GA E G GA G RG
Sbjct: 393 GGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEA 452
Query: 665 GSQS-PGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRPAAPPGP 723
G PG+ +D +D S E R P R PA P G
Sbjct: 453 GIPGVPGAKGEDGKDG-------------SPGEPGANGLPGAAGERGAPGFRGPAGPNGI 499
Query: 724 PGPAAPP----APSPAAPVRTRRRRKLYELHAAGAPP----PPPPGHAPAPESPR-PGSG 774
PG P AP PA P AAG P P PG P SP PGS
Sbjct: 500 PGEKGPAGERGAPGPAGP-----------RGAAGEPGRDGVPGGPGMRGMPGSPGGPGSD 548
Query: 775 SGSGPGLAPARSPGPAADGPIDLSKKPRRPLPGAPAPALADYHECTACRVSFHSLEAYLA 834
GP + S P GP +P + G P P D A
Sbjct: 549 GKPGPPGSQGESGRPGPPGPSGPRGQPG--VMGFPGPKGND--------------GAPGK 592
Query: 835 HKKYSCPAAP-PPGALGLPAAACPYCPPN--GPVRGDLLEHFRLAHGLLLGAP-LAGPGV 890
+ + P P P G G P PP GP GD + L G P GP
Sbjct: 593 NGERGGPGGPGPQGPPGKNGETGPQGPPGPTGP-GGDKGDTGPPGPQGLQGLPGTGGPPG 651
Query: 891 EARTPADRGPS-PAPAPAA------SPQPGSRGPRDGLGPEPQEPPPGPPPSPAAAPEAV 943
E P + GP A AP A + PG RGP GL P PP P A
Sbjct: 652 ENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGP-PGLAGAPGLRGGAGPPGPEGGKGAA 710
Query: 944 PPPPAPPSYSDKGVQ-TPSK--GTPAPLPNGN 972
PP P + G+Q P + G +P P G+
Sbjct: 711 GPPGPPGAAGTPGLQGMPGERGGLGSPGPKGD 742
Score = 76.6 bits (187), Expect = 1e-13
Identities = 163/670 (24%), Positives = 215/670 (32%), Gaps = 140/670 (20%)
Query: 376 PGSKGEIYSPGAGHPA--TKLPPDSLGSFQQQHTALQGPLASAD-------------LGL 420
PG+ GE +PG PA +P + + ++ GP +A G+
Sbjct: 479 PGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGM 538
Query: 421 APTPS-PGLDRKALAEATNGEA-RAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPIL-- 476
+P PG D K + GE+ R P G S P P + + + AP
Sbjct: 539 PGSPGGPGSDGKPGPPGSQGESGRPGP----PGPSGPRGQPGVMGFPGPKGNDGAPGKNG 594
Query: 477 ---GPGEPGPQAP---SRTPSPRSP----APARVKAELSSP-------------TPGSSP 513
GPG PGPQ P + P+ P P K + P PG +
Sbjct: 595 ERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENG 654
Query: 514 VPGELGLAGALFLPQYVFGP-DAAPPASEILAKMSELVHSRLQQGAGAGAGGAQTGLFPG 572
PGE G G P G DA P ++ R G GG PG
Sbjct: 655 KPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPG 714
Query: 573 APKGATCFECEITFSNVNNYYVHKRLYCSGRRAPEDAPAARRPKAPPGPARAP--PGQ-- 628
P A + G R +P + K PG A PG+
Sbjct: 715 PPGAAGTPGLQ---------------GMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDG 759
Query: 629 PAEPDAPRSSPGPGAR--EEGAGGAATPEDGAGGRGSEGSQS----------PGSSVDDA 676
P P P PGP + ++G GGA AG RGS G + PG+ +
Sbjct: 760 PRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNG 819
Query: 677 EDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRPAAPPGPPGPAAPPAPS--- 733
E +R + + P A PPG GPA PP P
Sbjct: 820 EPGGKG-------------------ERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVK 860
Query: 734 --------PAAPVRTRRRRKLYELHAAGAPPPPPPGHAPAPESPRPGSGSGSGPGLAPAR 785
P A R + G P PP P +P + P +G+ PG
Sbjct: 861 GERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVS 920
Query: 786 SPGPAADGPIDLSKKPRRPLPGAPAPALADYHECTACRVSFHSLEAYLAHKKYSCPAAPP 845
P A P + + PGAP P T R A PP
Sbjct: 921 GPKGDAGQPGEKGSPGAQGPPGAPGP--LGIAGITGARGL----------------AGPP 962
Query: 846 --PGALGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGP-GVEARTPADRGPSP 902
PG G P P G V+G+ + A+GL GP G+ P
Sbjct: 963 GMPGPRGSPG-------PQG-VKGESGKPG--ANGLSGERGPPGPQGLPGLAGTAGEPGR 1012
Query: 903 APAPAASPQPGSRGPRDGLGPEPQEPPPGPPPSPAAAPEAVPPPPAPPSYSDKGVQTPSK 962
P + PG G G G + PG P +P P PA S D+G P+
Sbjct: 1013 DGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKS-GDRGESGPAG 1071
Query: 963 GTPAPLPNGN 972
AP P G+
Sbjct: 1072 PAGAPGPAGS 1081
Score = 70.1 bits (170), Expect = 1e-11
Identities = 139/521 (26%), Positives = 169/521 (32%), Gaps = 87/521 (16%)
Query: 479 GEPGPQAPSRTPSPRSPAPARVKAELSSP-TPGSSPVPGELGLAGALFLPQYVFGPDAAP 537
G PGP P P P P SP +PG PGE G AG P GP A
Sbjct: 171 GYPGPAGP-----PGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPP----GPPGAI 221
Query: 538 PASEILAKMSELVH-----SRLQQGAGAGAGGAQTGLFPGAPKGATCFECEITFSNVNNY 592
S K E R G G A FPG KG F+
Sbjct: 222 GPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGM-KGHRGFDGR--------- 271
Query: 593 YVHKRLYCSGRRAPEDAPAARRPKAPPGPARAPPGQPAEPDAPRSSPGPGAREEGAGGAA 652
+G + AP + PG AP P PR +PG R G GAA
Sbjct: 272 --------NGEKGETGAPGLKGENGLPGENGAPG-----PMGPRGAPGERGRP-GLPGAA 317
Query: 653 TPEDGAGGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDP 712
G RGS+G P A S S R +P
Sbjct: 318 GARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAP------GQRGEP 371
Query: 713 PPRRPAAPPGPPGPAAPPAPSPAAPVRTRRRRKLYELHAAGAPPPP-------PPGHAPA 765
P+ A GPPGP SP E+ AG P P PPG PA
Sbjct: 372 GPQGHAGAQGPPGPPGING-SPGGK---------GEMGPAGIPGAPGLMGARGPPG--PA 419
Query: 766 PESPRPGSGSGSG-PGLAPAR-SPGPAADGPIDLSKKPRRPLPGAPAPALADYHECTACR 823
+ PG G+G PG A+ PGP + + +PG P D + +
Sbjct: 420 GANGAPGLRGGAGEPGKNGAKGEPGPRGE-------RGEAGIPGVPGAKGEDGKDGSPGE 472
Query: 824 VSFHSLEAYLAHK---KYSCPAAPP--PGALGLPAAACPYCPPNGPVRGDLLEHFRLAHG 878
+ L + + PA P PG G PA P GP RG E R G
Sbjct: 473 PGANGLPGAAGERGAPGFRGPAGPNGIPGEKG-PAGERGAPGPAGP-RGAAGEPGR--DG 528
Query: 879 LLLGAPLAG-PGVEARTPADRGPSPAPAPAASPQPGSRGPRDGLGPEPQEPPPGPPPSPA 937
+ G + G PG +D P P + S +PG GP G PGP +
Sbjct: 529 VPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDG 588
Query: 938 A----APEAVPPPPAPPSYSDKGVQTPSKGTPAPLPNGNHR 974
A P P P K +T +G P P G +
Sbjct: 589 APGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDK 629
Score = 69.7 bits (169), Expect = 1e-11
Identities = 107/389 (27%), Positives = 132/389 (33%), Gaps = 50/389 (12%)
Query: 596 KRLYCSGRRAPEDAPAARRPKAPPGPARAPPGQPAEPDAPRSSPGPGAREEGAGGAATPE 655
+ L C P A P+ P P R P GQ P P+ PGP G P
Sbjct: 70 QELDCPNPEIPFGECCAVCPQPPTAPTRPPNGQG--PQGPKGDPGPPGIPGRNGDPGIP- 126
Query: 656 DGAGGRGSEGSQSPGSSVDDAEDDPSRTLCEACNI---RFS-RHETYTVHKRYYCASRHD 711
G GS GS P +CE+C +S ++++Y V
Sbjct: 127 ---GQPGSPGSPGPPG------------ICESCPTGPQNYSPQYDSYDVKSGVAVGGLAG 171
Query: 712 -PPPRRPAAPPGPPGPAAPPAPSPAAPVRTRRRRKLYELHAAGAPPPPPPGHAPAPESPR 770
P P P PPGPPG + P SP +P + E AG PP P A P P
Sbjct: 172 YPGPAGPPGPPGPPGTSGHPG-SPGSP---GYQGPPGEPGQAGPSGPPGPPGAIGPSGPA 227
Query: 771 PGSGSGSGPGLAPARS-PG-PAADGPIDLSKKPRRPLPGAPAPALADYHECTACRVSFHS 828
G PG R PG P GP + PG D
Sbjct: 228 GKDGESGRPGRPGERGLPGPPGIKGPAGIP-----GFPGMKGHRGFDGRNGEKGETGAPG 282
Query: 829 LEAYLAHKKYSCPAAPPPGALGLPA-AACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAG 887
L+ + A P G G P P P RG+ + R + G G P G
Sbjct: 283 LKGENGLPGEN-GAPGPMGPRGAPGERGRPGLPGAAGARGN--DGARGSDG-QPGPP--G 336
Query: 888 PGVEARTPADRGP----SPAPAPAASPQPGSRGPRDGLGPEPQEPPPGPP---PSPAAAP 940
P A P G PA +P ++ PG RG G + PPGPP SP
Sbjct: 337 PPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKG 396
Query: 941 EAVPP--PPAPPSYSDKGVQTPSKGTPAP 967
E P P AP +G P+ AP
Sbjct: 397 EMGPAGIPGAPGLMGARGPPGPAGANGAP 425
Score = 65.9 bits (159), Expect = 2e-10
Identities = 147/551 (26%), Positives = 170/551 (30%), Gaps = 94/551 (17%)
Query: 469 EPEAAPILGPGEPGPQAPSRTPSPRSPAPARVKAELSSPTPGSSPVPGELGLAGALFLPQ 528
+P AP P GPQ P P P P R PGS PG G+ +
Sbjct: 90 QPPTAPTRPPNGQGPQGPKGDPGPPG-IPGRNGDPGIPGQPGSPGSPGPPGICESC---- 144
Query: 529 YVFGPDAAPPASEILAKMSELVHSRLQQGAGAGAGGAQTGLFPGAPKGATCFECEITFSN 588
GP P + S V S + G AG G P P G +
Sbjct: 145 -PTGPQNYSPQYD-----SYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPG--- 195
Query: 589 VNNYYVHKRLYCSGRRAPEDAPAARRPKAPPGPARA-----PPGQPAEPDAP-----RSS 638
G + P P P PPGP A P G+ E P R
Sbjct: 196 -----------SPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGL 244
Query: 639 PGPGAREEGAGGAATP----EDGAGGRGSEGSQSPGSSVDDAEDDPSRTLCEA-CNIRFS 693
PGP + AG P G GR E ++ + P R +
Sbjct: 245 PGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGA 304
Query: 694 RHETYTVHKRYYCASRHDPPPRRPAAPPGPPGPAAPPAPSPAAPVRTRRRRKLYELHAAG 753
E +R + R PGPPGP A P +P + G
Sbjct: 305 PGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPG-TAGFPGSPGAKGEVGPAGSPGSNG 363
Query: 754 AP----PPPPPGHAPAPESPRP----GSGSGSG----------PGLAPARS-PGPA-ADG 793
AP P P GHA A P P GS G G PGL AR PGPA A+G
Sbjct: 364 APGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANG 423
Query: 794 PIDLSKKPRRP----LPGAPAPALADYHECTACRVSFHSLEAYLAHKKYSCPAAPPPGAL 849
L P G P P + E V E K P PGA
Sbjct: 424 APGLRGGAGEPGKNGAKGEPGPR-GERGEAGIPGVPGAKGE----DGKDGSPG--EPGAN 476
Query: 850 GLPAAACPYCPP--NGPVRGDLLEHFRLAHGLLLGAP-LAGPGVEARTPADRGPSPA--- 903
GLP AA P GP + G P GP E P GP A
Sbjct: 477 GLPGAAGERGAPGFRGPAGPN-------------GIPGEKGPAGERGAPGPAGPRGAAGE 523
Query: 904 PAPAASP-QPGSRGPRDGLGPEPQEPPPGPPPSPAAAPEAVPPPPAPPSYSD--KGVQTP 960
P P PG RG G + PGPP S + PP P+ P G P
Sbjct: 524 PGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGP 583
Query: 961 SKGTPAPLPNG 971
AP NG
Sbjct: 584 KGNDGAPGKNG 594
Score = 42.4 bits (98), Expect = 0.002
Identities = 70/292 (23%), Positives = 88/292 (30%), Gaps = 54/292 (18%)
Query: 377 GSKGEIYSPGA-GHPATKLPPDSLGSFQQQHTALQGPLASADLGLAPTPSPGLDRKALAE 435
G KGE PGA G + PP G TA + D PG D +
Sbjct: 975 GVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGE---PGRDGNPGSDGLPGRDGSPGGK 1031
Query: 436 ATNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILGPGEPGPQAPSRTPSPRSP 495
GE P A P P ++ + E+ P G PGP P P+ P
Sbjct: 1032 GDRGE-NGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGP 1090
Query: 496 APARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGPDAAPPASEILAKMSELVHSRLQ 555
+ G + G G+ G P P + PA Q
Sbjct: 1091 RGDK----------GETGERGAAGIKGHRGFPGNPGAPGSPGPAG--------------Q 1126
Query: 556 QGA--GAGAGGAQTGLFPGAPKGATCFECEITFSNVNNYYVHKRLYCSGRRAPEDAPAAR 613
QGA G G + + P P G SG P P R
Sbjct: 1127 QGAIGSPGPAGPRGPVGPSGPPGKDG--------------------TSGHPGPIGPPGPR 1166
Query: 614 RPKAPPGPARAPPGQPAEPDAPRSSPGPGAREEGAGGAATPEDGAGGRGSEG 665
+ G + PG P +P P PG G G AA G GG + G
Sbjct: 1167 GNRGERG-SEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAIA--GIGGEKAGG 1215
>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
sapiens]
Length = 1691
Score = 81.6 bits (200), Expect = 3e-15
Identities = 139/537 (25%), Positives = 166/537 (30%), Gaps = 115/537 (21%)
Query: 478 PGEPGPQAPSRTPSPRSPAPARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGPDAAP 537
PG PGP + P P + + P +PG GL G P P
Sbjct: 382 PGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGL---PGPPG 438
Query: 538 PASEILAKMSELVHSRLQQGAGA-GAGGAQTGLFPGAPKGATCFECEITFSNVNNYYVHK 596
PA + E+ G+ G G Q KG TCF C T
Sbjct: 439 PAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGT----------- 487
Query: 597 RLYCSGRRAPEDAPAARRPKAPPGP--------------ARAPPGQPAEPDAPRSSPGPG 642
G P P PPG A P G P P AP + PG
Sbjct: 488 -----GISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPG 542
Query: 643 AREEGAGGAATPEDGAGGRGSEGSQS-------PGSSVDDAEDDPSRTLCEACNIRFSRH 695
++ E G T G +G GS PG+ D E I F
Sbjct: 543 SKGE-PGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGE 601
Query: 696 ETYTVHKRYYCASRHDPPPRRPAAP--PGPPGPAAPPAPSPAAPVRTRRRRKLYELHAAG 753
PP P P PG GP PP P PV + + + G
Sbjct: 602 R---------------GPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGV--AGNPG 644
Query: 754 APPPPPPGHAPAPESPRPGSGSGSGPGLAPARSPG-PAADGPIDLSKKPRRP----LPGA 808
P P P P +PG PGL PG P DG + L P P LPG
Sbjct: 645 QPGIPGPKGDPGQTITQPGK-----PGL-----PGNPGRDGDVGLPGDPGLPGQPGLPGI 694
Query: 809 PA----PALADYHECTACRVSFHSLEAYLAHKKYSCPAAP-PPGALGLPAAACPYCPPNG 863
P P + L K + P P PPGA G P PP
Sbjct: 695 PGSKGEPGIPGI-----------GLPGPPGPKGF--PGIPGPPGAPGTPGRIGLEGPPGP 741
Query: 864 P----VRGDLLEHFRLAHGLLLGAPLAGPGVEARTPA-----DRG-PSPAPAPAASPQPG 913
P +G+ G L P PG+ A DRG P P P + G
Sbjct: 742 PGFPGPKGE--------PGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDG 793
Query: 914 SRGPRDGLGPEPQEPPPGPPPSPAAAPEAVPPPPA-PPSYSDKGVQ--TPSKGTPAP 967
GP+ +GP Q P GPP P + P PP P G+ KG P P
Sbjct: 794 LPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGP 850
Score = 71.2 bits (173), Expect = 4e-12
Identities = 159/665 (23%), Positives = 214/665 (32%), Gaps = 124/665 (18%)
Query: 377 GSKGEIYSPGA-------GHPATKLPPDSLGSFQQQHTALQGPLASADL----GLAPTP- 424
G KGE PG G P + PP G Q+ + GP + GL P
Sbjct: 45 GEKGERGFPGLEGHPGLPGFPGPEGPPGPRG--QKGDDGIPGPPGPKGIRGPPGLPGFPG 102
Query: 425 SPGLDRKALAEATNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILGPGEPGPQ 484
+PGL + G G P +P ++ P P + GEPG
Sbjct: 103 TPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGM-KGEPGSI 161
Query: 485 APSRTPSPRS----PAPARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGPDAAPPAS 540
S P P+ P P ++ PG + +PG +G G P + GP P
Sbjct: 162 IMSSLPGPKGNPGYPGPPGIQG-----LPGPTGIPGPIGPPG----PPGLMGPPGPPGLP 212
Query: 541 EILAKMSELVHSRLQQGAGAGAGGAQTGLFPGAPKGATCFE---CEITFSNVNNYYVHKR 597
M L G G Q P P G + ++ F +
Sbjct: 213 GPKGNMG------LNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGL---- 262
Query: 598 LYCSGRRAPEDAPAARRPKAPPGPARAPPGQPAEPDAPRSSPGPGAREEGAGGAATPEDG 657
G R P P R P PPG + G+ EP R PG G P D
Sbjct: 263 ---PGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEP-GKRGKPGKDGENGQPGIPGLPGDP 318
Query: 658 A--------GGRGSEGSQSPGSSVDDAEDDPSR--TLCEACNIRFSRHETYTVHKRYYCA 707
G +G +G P P T+ E NI + +
Sbjct: 319 GYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGF--- 375
Query: 708 SRHDPPPRRPAAPPGPPGPAAPPAPSPAAPVRTRRRRKLYELHAAGAPPPPPPGHAPAPE 767
P + P PGPPG A P P P R + + G P PPG P
Sbjct: 376 ----PGIQGPPGLPGPPGAAVMGPPGP--PGFPGERGQKGDEGPPGISIPGPPGLDGQPG 429
Query: 768 SP-RPGSGSGSGPGLAPAR---SPGPAA--DGPID------------------------L 797
+P PG +GP + P+ PGP P D +
Sbjct: 430 APGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGI 489
Query: 798 SKKPRRP-LPGAPAPALADYHECTACRVSFHSLEAYLAHKKYSCPAAPPPGALGLPAA-A 855
S P +P LPG P P + + F + +K A P G G+P A
Sbjct: 490 SGPPGQPGLPGLPGPPGS---------LGFPGQKG----EKGQAGATGPKGLPGIPGAPG 536
Query: 856 CPYCPPNGPVRGDLLEHFRLAHGL-LLGAPLAGPGVEARTPADRGPSPAPAPAASPQPGS 914
P P + GD+L + LG+P PG+ P G P PG
Sbjct: 537 APGFPGSKGEPGDILTFPGMKGDKGELGSP-GAPGLPG-LPGTPGQDGLPG-----LPGP 589
Query: 915 RGPRDGLGPEPQEPPPGPPPSPAAAPEAVPPPP----APPSYSDKGVQ--TPSKGTPA-P 967
+G G+ + + PPG P P P P P +KG+Q + G P P
Sbjct: 590 KGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIP 649
Query: 968 LPNGN 972
P G+
Sbjct: 650 GPKGD 654
Score = 62.4 bits (150), Expect = 2e-09
Identities = 161/675 (23%), Positives = 206/675 (30%), Gaps = 161/675 (23%)
Query: 376 PGSKGEIYSPGAG---------HPATKLPPDSLGSFQQQHTALQGPLA-------SADLG 419
PGSKGE PG G P PP + G+ L+GP + G
Sbjct: 695 PGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGT--PGRIGLEGPPGPPGFPGPKGEPG 752
Query: 420 LA---PTPSPGLDRKALAEATNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPIL 476
A P PGL A G+ G PP P ++ + P+ +
Sbjct: 753 FALPGPPGPPGLPGFKGALGPKGDR---------GFPGPPGPPGRTGLDGLPGPKGD--V 801
Query: 477 GP-GEPGPQAPSRTPS---------PRSPAPAR------VKAELSSPTPGSSPVPGELGL 520
GP G+PGP P P P P P + E P P VPG G
Sbjct: 802 GPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGE 861
Query: 521 AGALFLPQYVFGPDAAPPASEILAKMSELVHSRLQQGAGA----GAGGAQTGLFPGAPKG 576
G+ +P GP P + + K AGA G G + P P G
Sbjct: 862 RGSPGIPGAP-GPIGPPGSPGLPGK------------AGASGFPGTKGEMGMMGPPGPPG 908
Query: 577 ATCFECEITFSNVNNYYVHKRLYC-------SGRRAPEDAPAARRPKAPPGP----ARAP 625
S V L +G + + P P P P ++
Sbjct: 909 PLGIPGR---SGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGE 965
Query: 626 PGQPAEPDAPRSSPGPGAR----EEGAGGAATPEDGAGGRGSEGSQSPGSSVDDAEDDPS 681
G+P P P S G + + G G + G G +G+ PG P
Sbjct: 966 KGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGN--PGLPGQPGLIGPP 1023
Query: 682 RTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRPAAPPGPPG-PAAPPAPSPAAPVRT 740
++ F P P+ PPGP G P P +P
Sbjct: 1024 GLKGTIGDMGF-------------------PGPQGVEGPPGPSGVPGQPGSPGLPGQKGD 1064
Query: 741 RRRRKLYELHAAGAP-PPPPPGHAPAPESP-------------RPGSGSGSG-PGLAPAR 785
+ + + G P P PG P +P PG+ G PGL P
Sbjct: 1065 KGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGL-PGF 1123
Query: 786 SPGPAADGPIDLSKKPRRP-LPGAPAPALADYHECTACRVSFHSLEAYLAHKKYSCPAAP 844
P GP +S P P LPG P P H P P
Sbjct: 1124 PGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHP--------------------GQPGPP 1163
Query: 845 ----PPGALGLPAAACPYCPPNGPVRGDLLE------HFRLAHGLLLGAP----LAGPGV 890
PG G+P A P P G+ + G L G P L GP
Sbjct: 1164 GEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKG 1223
Query: 891 EARTPADRGPSPAPAPAASPQPGSRGPRDGLGPEPQEPPPGPPPSPAAAPEAVPPPPAPP 950
E G P P SP P GP+ P PQ PP P P+ + +P P PP
Sbjct: 1224 EPGFHGFPGVQGPPGPPGSPGPALEGPKG--NPGPQGPPGRPGPT---GFQGLPGPEGPP 1278
Query: 951 SYSDKGVQTPSKGTP 965
G KG P
Sbjct: 1279 GLPGNGGIKGEKGNP 1293
Score = 62.0 bits (149), Expect = 3e-09
Identities = 156/654 (23%), Positives = 192/654 (29%), Gaps = 144/654 (22%)
Query: 376 PGSKGEIYSPGAGHPATKLPPDSLGSFQQQHTALQGPLASADLGLAPTPSPGLDRKALAE 435
PG KG+ PG P PP GS + A + P SPGL KA A
Sbjct: 842 PGEKGDPGPPGLDVPG---PPGERGS---------PGIPGAPGPIGPPGSPGLPGKAGAS 889
Query: 436 A---TNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILG-PGEPGPQAPSRTPS 491
T GE G PP P + + P + + G G+ G Q P
Sbjct: 890 GFPGTKGEM---------GMMGPPGPPGPLGI-----PGRSGVPGLKGDDGLQGQPGLPG 935
Query: 492 PRSPAPARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGPDAAPPASEILAKMSELVH 551
P + K E P P P LG G P P + P +
Sbjct: 936 PTGEKGS--KGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKG----------Y 983
Query: 552 SRLQQGAGAGAGGAQTGL-FPGAPKGATCFECEITFSNVNNYYVHKRLYCSGRRAPEDAP 610
L G Q GL P PKG + G P
Sbjct: 984 QGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGL--------KGTIGDMGFP 1035
Query: 611 AARRPKAPPGPARAP--PGQPAEPDAPRSSPGPGAREEGAGGAATPEDGAGGRGSEGSQS 668
+ + PPGP+ P PG P P PG G G P+ G G G+
Sbjct: 1036 GPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPG 1095
Query: 669 PGSSVDD-----------AEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRP 717
SV D A+ P + + P P+
Sbjct: 1096 IKGSVGDPGLPGLPGTPGAKGQPGLP--------------------GFPGTPGPPGPKGI 1135
Query: 718 AAPPGPPGPAAPPAP-----SPAAPVRTRRRRKLYELHAAGAP----PPPPPGHAPAPES 768
+ PPG PG P P P P + K + G P PG
Sbjct: 1136 SGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPP 1195
Query: 769 PRPGSGSGSGPGLAPARSPGPAADGP--------IDLSKKPRRPLPGAPAPALADYHECT 820
PG G G P P GP + P P PG+P PAL
Sbjct: 1196 GLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGP-PGSPGPALE------ 1248
Query: 821 ACRVSFHSLEAYLAHKKYSCPAAPP--PGALGLPAAACPYCPPNGPVRGDLL-EHFRLAH 877
K P PP PG G P PP P G + E
Sbjct: 1249 -------------GPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQ 1295
Query: 878 GLLLGAP-LAG----PGVEAR--TPADRGPSPAPA-PAASPQPGSRGPR---DGLGPEPQ 926
L G P L G PG++ P G P P PG +GP GPE +
Sbjct: 1296 PGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGE 1355
Query: 927 E---PPPGPPPSPAAAPEAV------PPPPAPPSYSDKGVQTPSKGTPAPLPNG 971
PPGPP P + +++ PP P KG+ P P P G
Sbjct: 1356 PGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTG 1409
Score = 59.3 bits (142), Expect = 2e-08
Identities = 148/630 (23%), Positives = 180/630 (28%), Gaps = 157/630 (24%)
Query: 375 QPGSKGEIYSPGAGHPATKLPPDSLGSFQQQ-HTALQG-PLASADLGLAPTPS----PGL 428
+ GSKGE PG P + P+ LGS ++ L G P S G P PGL
Sbjct: 939 EKGSKGE---PGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGL 995
Query: 429 DRKALAEATNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILGPGEPGPQAPSR 488
+ G L G PP +I P+ G GP PS
Sbjct: 996 SGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQ-------GVEGPPGPSG 1048
Query: 489 TPS-PRSPAPARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGPDAAPPASEILAKMS 547
P P SP K + P S +PG G G LP Y P +
Sbjct: 1049 VPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGD------ 1102
Query: 548 ELVHSRLQQGAGAGAGGAQTGL--FPGAPKGATCFECEITFSNVNNYYVHKRLYCSGRRA 605
L G Q GL FPG P G
Sbjct: 1103 ----PGLPGLPGTPGAKGQPGLPGFPGTPGPPGP---------------------KGISG 1137
Query: 606 PEDAPAARRPKAPPGPARAP--PGQPAEPDAPRSS--PGPGAREEGAGGAATPEDGAGGR 661
P P P G P PG P E P PGP ++ G G G
Sbjct: 1138 PPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGL 1197
Query: 662 GSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRPAAPP 721
Q + +P + + E P + P PP
Sbjct: 1198 PGLSGQKGDGGLPGIPGNPG--------LPGPKGEP---------GFHGFPGVQGPPGPP 1240
Query: 722 GPPGPAAPPA---PSPAAPVRTRRRRKLYELHAAGAPPPPPPGHAPAPESP--RPGSGSG 776
G PGPA P P P G P P P PE P PG+G
Sbjct: 1241 GSPGPALEGPKGNPGPQGP--------------PGRPGPTGFQGLPGPEGPPGLPGNGGI 1286
Query: 777 SG-------PGLAPARSPGPAAD-GPIDLSKKPRRP----------LPGAPAPALADYHE 818
G PGL PG D GP L P RP LPG P
Sbjct: 1287 KGEKGNPGQPGLPGL--PGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVP--------- 1335
Query: 819 CTACRVSFHSLEAYLAHKKYSCPAAPP--PGALGLPAAACPYCPPNGPVRGDLLEHFRLA 876
F ++ P+ P G G P P PP P
Sbjct: 1336 ------GFPGMKG---------PSGVPGSAGPEGEPGLIGPPGPPGLPGPS--------G 1372
Query: 877 HGLLLGAPLAGPGVEAR-----TPADRGPSPAPAPAASP-QPGSRGPRDGLGPEPQEPPP 930
+++ PG+ + P +GP P P P PG G G ++ P
Sbjct: 1373 QSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDP 1432
Query: 931 GPPPSPAA-------APEAVPPPPAPPSYS 953
G P P P+ + PP PP S
Sbjct: 1433 GLPGQPGTRGLDGPPGPDGLQGPPGPPGTS 1462
Score = 54.7 bits (130), Expect = 4e-07
Identities = 172/698 (24%), Positives = 207/698 (29%), Gaps = 152/698 (21%)
Query: 376 PGSKGEIYSPGA-------GHPATKLPPDSLGSFQQQHTALQGPLASADLGLAPTP-SPG 427
PG KGE GA G P P GS + L P D G +P +PG
Sbjct: 511 PGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPG 570
Query: 428 LDRKALAEATNG-EARAEPLAQNGGSS-----EPPAAPRSIKVEAVEEPEAAPILGP--- 478
L +G P + GG + PP P + P P GP
Sbjct: 571 LPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGP 630
Query: 479 -GEPGPQAPSRTPS-PRSPAPARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGPDAA 536
GE G Q + P P P P + + PG +PG G G + LP D
Sbjct: 631 VGEKGIQGVAGNPGQPGIPGPKGDPGQTITQ-PGKPGLPGNPGRDGDVGLPG-----DPG 684
Query: 537 PPASEILAKMSELVHSRLQQGAGAGAGGAQTGLFPG--APKGATCFECEITFSNVNNYYV 594
P L + G G G FPG P GA I
Sbjct: 685 LPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKG-FPGIPGPPGAPGTPGRI---------- 733
Query: 595 HKRLYCSGRRAPEDAPAARRPKAPPGPAR-APPGQPAEPD-----APRSS------PGPG 642
G P P PK PG A PPG P P P+ PGP
Sbjct: 734 -------GLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPP 786
Query: 643 AREEGAGGAATPEDGAGGRGSEGSQSP----GSSVDDAEDDPSRTLCEACNIRFSRHETY 698
R G G P+ G G G P G V P + +
Sbjct: 787 GRT-GLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPG------IPGPIGQPGLH 839
Query: 699 TVHKRYYCASRHDP---------PPRRPAAP--PGPPGPAAPPAPSPAAPVRTRRRR--- 744
+ + DP PP +P PG PGP PP SP P +
Sbjct: 840 GIP-----GEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPG-SPGLPGKAGASGFPG 893
Query: 745 KLYELHAAGAPPPPPPGHAPAPESPRPGSGSGSG----PGLAPARSPGPAADGPIDLSKK 800
E+ G P PP P P S PG G PGL PGP + K
Sbjct: 894 TKGEMGMMGPPGPPGPLGIPG-RSGVPGLKGDDGLQGQPGL-----PGPTGEK----GSK 943
Query: 801 PRRPLPGAPAPALADY--HECTACRVSFHSLEAYLAHKKYSCPAAPP-----PGALGLPA 853
LPG P P + + + K Y P G GLP
Sbjct: 944 GEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPG 1003
Query: 854 AACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGP-GVEARTPADRGPSPAPAPAASPQ- 911
P P P + L+ L G + GP GVE GPS P SP
Sbjct: 1004 PPGPKGNPGLPGQPGLIGPPGLK-GTIGDMGFPGPQGVEGPP----GPSGVPGQPGSPGL 1058
Query: 912 PGSRGPRDGLG---------PEPQEPP--------------------PGPPPSPAAAPE- 941
PG +G + G P P+ P PG P +P A +
Sbjct: 1059 PGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQP 1118
Query: 942 ------AVPPPPAPPSYSDKGVQTPSKGTPAPLPNGNH 973
P PP P S G P P+ G H
Sbjct: 1119 GLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGH 1156
Score = 31.6 bits (70), Expect = 3.9
Identities = 52/188 (27%), Positives = 63/188 (33%), Gaps = 30/188 (15%)
Query: 377 GSKGEIYSPGA----GHPATKL---PPDSLGSFQQQHTALQGPLASADLGLAPTPS-PGL 428
G KGE +PG G P K PP G+ L G D GL P PG+
Sbjct: 1285 GIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGN--PGRPGLNG--MKGDPGLPGVPGFPGM 1340
Query: 429 DRKALAEATNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILGPGEPG------ 482
+ + G L G PP P + + +A P PG+PG
Sbjct: 1341 KGPSGVPGSAGPEGEPGLI---GPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPG 1397
Query: 483 PQAPSRTPSPRSP--------APARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGPD 534
PQ P P P P P A PG PG GL G P + GP
Sbjct: 1398 PQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPG-PDGLQGPP 1456
Query: 535 AAPPASEI 542
P S +
Sbjct: 1457 GPPGTSSV 1464
>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
sapiens]
Length = 1685
Score = 81.6 bits (200), Expect = 3e-15
Identities = 139/537 (25%), Positives = 166/537 (30%), Gaps = 115/537 (21%)
Query: 478 PGEPGPQAPSRTPSPRSPAPARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGPDAAP 537
PG PGP + P P + + P +PG GL G P P
Sbjct: 382 PGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGL---PGPPG 438
Query: 538 PASEILAKMSELVHSRLQQGAGA-GAGGAQTGLFPGAPKGATCFECEITFSNVNNYYVHK 596
PA + E+ G+ G G Q KG TCF C T
Sbjct: 439 PAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGT----------- 487
Query: 597 RLYCSGRRAPEDAPAARRPKAPPGP--------------ARAPPGQPAEPDAPRSSPGPG 642
G P P PPG A P G P P AP + PG
Sbjct: 488 -----GISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPG 542
Query: 643 AREEGAGGAATPEDGAGGRGSEGSQS-------PGSSVDDAEDDPSRTLCEACNIRFSRH 695
++ E G T G +G GS PG+ D E I F
Sbjct: 543 SKGE-PGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGE 601
Query: 696 ETYTVHKRYYCASRHDPPPRRPAAP--PGPPGPAAPPAPSPAAPVRTRRRRKLYELHAAG 753
PP P P PG GP PP P PV + + + G
Sbjct: 602 R---------------GPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGV--AGNPG 644
Query: 754 APPPPPPGHAPAPESPRPGSGSGSGPGLAPARSPG-PAADGPIDLSKKPRRP----LPGA 808
P P P P +PG PGL PG P DG + L P P LPG
Sbjct: 645 QPGIPGPKGDPGQTITQPGK-----PGL-----PGNPGRDGDVGLPGDPGLPGQPGLPGI 694
Query: 809 PA----PALADYHECTACRVSFHSLEAYLAHKKYSCPAAP-PPGALGLPAAACPYCPPNG 863
P P + L K + P P PPGA G P PP
Sbjct: 695 PGSKGEPGIPGI-----------GLPGPPGPKGF--PGIPGPPGAPGTPGRIGLEGPPGP 741
Query: 864 P----VRGDLLEHFRLAHGLLLGAPLAGPGVEARTPA-----DRG-PSPAPAPAASPQPG 913
P +G+ G L P PG+ A DRG P P P + G
Sbjct: 742 PGFPGPKGE--------PGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDG 793
Query: 914 SRGPRDGLGPEPQEPPPGPPPSPAAAPEAVPPPPA-PPSYSDKGVQ--TPSKGTPAP 967
GP+ +GP Q P GPP P + P PP P G+ KG P P
Sbjct: 794 LPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGP 850
Score = 71.2 bits (173), Expect = 4e-12
Identities = 159/665 (23%), Positives = 214/665 (32%), Gaps = 124/665 (18%)
Query: 377 GSKGEIYSPGA-------GHPATKLPPDSLGSFQQQHTALQGPLASADL----GLAPTP- 424
G KGE PG G P + PP G Q+ + GP + GL P
Sbjct: 45 GEKGERGFPGLEGHPGLPGFPGPEGPPGPRG--QKGDDGIPGPPGPKGIRGPPGLPGFPG 102
Query: 425 SPGLDRKALAEATNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILGPGEPGPQ 484
+PGL + G G P +P ++ P P + GEPG
Sbjct: 103 TPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGM-KGEPGSI 161
Query: 485 APSRTPSPRS----PAPARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGPDAAPPAS 540
S P P+ P P ++ PG + +PG +G G P + GP P
Sbjct: 162 IMSSLPGPKGNPGYPGPPGIQG-----LPGPTGIPGPIGPPG----PPGLMGPPGPPGLP 212
Query: 541 EILAKMSELVHSRLQQGAGAGAGGAQTGLFPGAPKGATCFE---CEITFSNVNNYYVHKR 597
M L G G Q P P G + ++ F +
Sbjct: 213 GPKGNMG------LNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGL---- 262
Query: 598 LYCSGRRAPEDAPAARRPKAPPGPARAPPGQPAEPDAPRSSPGPGAREEGAGGAATPEDG 657
G R P P R P PPG + G+ EP R PG G P D
Sbjct: 263 ---PGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEP-GKRGKPGKDGENGQPGIPGLPGDP 318
Query: 658 A--------GGRGSEGSQSPGSSVDDAEDDPSR--TLCEACNIRFSRHETYTVHKRYYCA 707
G +G +G P P T+ E NI + +
Sbjct: 319 GYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGF--- 375
Query: 708 SRHDPPPRRPAAPPGPPGPAAPPAPSPAAPVRTRRRRKLYELHAAGAPPPPPPGHAPAPE 767
P + P PGPPG A P P P R + + G P PPG P
Sbjct: 376 ----PGIQGPPGLPGPPGAAVMGPPGP--PGFPGERGQKGDEGPPGISIPGPPGLDGQPG 429
Query: 768 SP-RPGSGSGSGPGLAPAR---SPGPAA--DGPID------------------------L 797
+P PG +GP + P+ PGP P D +
Sbjct: 430 APGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGI 489
Query: 798 SKKPRRP-LPGAPAPALADYHECTACRVSFHSLEAYLAHKKYSCPAAPPPGALGLPAA-A 855
S P +P LPG P P + + F + +K A P G G+P A
Sbjct: 490 SGPPGQPGLPGLPGPPGS---------LGFPGQKG----EKGQAGATGPKGLPGIPGAPG 536
Query: 856 CPYCPPNGPVRGDLLEHFRLAHGL-LLGAPLAGPGVEARTPADRGPSPAPAPAASPQPGS 914
P P + GD+L + LG+P PG+ P G P PG
Sbjct: 537 APGFPGSKGEPGDILTFPGMKGDKGELGSP-GAPGLPG-LPGTPGQDGLPG-----LPGP 589
Query: 915 RGPRDGLGPEPQEPPPGPPPSPAAAPEAVPPPP----APPSYSDKGVQ--TPSKGTPA-P 967
+G G+ + + PPG P P P P P +KG+Q + G P P
Sbjct: 590 KGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIP 649
Query: 968 LPNGN 972
P G+
Sbjct: 650 GPKGD 654
Score = 62.4 bits (150), Expect = 2e-09
Identities = 156/652 (23%), Positives = 194/652 (29%), Gaps = 146/652 (22%)
Query: 376 PGSKGEIYSPGAGHPATKLPPDSLGSFQQQHTALQGPLASADLGLAPTPSPGLDRKALAE 435
PG KG+ PG P PP GS + A + P SPGL KA A
Sbjct: 842 PGEKGDPGPPGLDVPG---PPGERGS---------PGIPGAPGPIGPPGSPGLPGKAGAS 889
Query: 436 A---TNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILG-PGEPGPQAPSRTPS 491
T GE G PP P + + P + + G G+ G Q P
Sbjct: 890 GFPGTKGEM---------GMMGPPGPPGPLGI-----PGRSGVPGLKGDDGLQGQPGLPG 935
Query: 492 PRSPAPARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGPDAAPPASEILAKMSELVH 551
P + K E P P P LG G P P + P +
Sbjct: 936 PTGEKGS--KGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKG----------Y 983
Query: 552 SRLQQGAGAGAGGAQTGL-FPGAPKGATCFECEITFSNVNNYYVHKRLYCSGRRAPEDAP 610
L G Q GL P PKG + G P
Sbjct: 984 QGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGL--------KGTIGDMGFP 1035
Query: 611 AARRPKAPPGPARAP--PGQPAEPDAPRSSPGPGAREEGAGGAATPEDGAGGRGSEGSQS 668
+ + PPGP+ P PG P P PG G G P+ G G G+
Sbjct: 1036 GPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPG 1095
Query: 669 PGSSVDD-----------AEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRP 717
SV D A+ P + + P P+
Sbjct: 1096 IKGSVGDPGLPGLPGTPGAKGQPGLP--------------------GFPGTPGPPGPKGI 1135
Query: 718 AAPPGPPGPAAPPAP-----SPAAPVRTRRRRKLYELHAAGAP----PPPPPGHAPAPES 768
+ PPG PG P P P P + K + G P PG
Sbjct: 1136 SGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPP 1195
Query: 769 PRPGSGSGSGPGLAPARSPGPAADGP--------IDLSKKPRRPLPGAPAPALADYHECT 820
PG G G P P GP + P P PG+P PAL
Sbjct: 1196 GLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGP-PGSPGPALEG----- 1249
Query: 821 ACRVSFHSLEAYLAHKKYSCPAAPPPGALGLPA-AACPYCPPNGPVRGDLLEHFRLAHGL 879
K + PPG GLP P P NG ++G E
Sbjct: 1250 ---------------PKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKG---EKGNPGQPG 1291
Query: 880 LLGAP-LAG----PGVEAR--TPADRGPSPAPA-PAASPQPGSRGPR---DGLGPEPQE- 927
L G P L G PG++ P G P P PG +GP GPE +
Sbjct: 1292 LPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPG 1351
Query: 928 --PPPGPPPSPAAAPEAV------PPPPAPPSYSDKGVQTPSKGTPAPLPNG 971
PPGPP P + +++ PP P KG+ P P P G
Sbjct: 1352 LIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTG 1403
Score = 60.1 bits (144), Expect = 1e-08
Identities = 160/675 (23%), Positives = 204/675 (30%), Gaps = 167/675 (24%)
Query: 376 PGSKGEIYSPGAG---------HPATKLPPDSLGSFQQQHTALQGPLA-------SADLG 419
PGSKGE PG G P PP + G+ L+GP + G
Sbjct: 695 PGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGT--PGRIGLEGPPGPPGFPGPKGEPG 752
Query: 420 LA---PTPSPGLDRKALAEATNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPIL 476
A P PGL A G+ G PP P ++ + P+ +
Sbjct: 753 FALPGPPGPPGLPGFKGALGPKGDR---------GFPGPPGPPGRTGLDGLPGPKGD--V 801
Query: 477 GP-GEPGPQAPSRTPS---------PRSPAPAR------VKAELSSPTPGSSPVPGELGL 520
GP G+PGP P P P P P + E P P VPG G
Sbjct: 802 GPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGE 861
Query: 521 AGALFLPQYVFGPDAAPPASEILAKMSELVHSRLQQGAGA----GAGGAQTGLFPGAPKG 576
G+ +P GP P + + K AGA G G + P P G
Sbjct: 862 RGSPGIPGAP-GPIGPPGSPGLPGK------------AGASGFPGTKGEMGMMGPPGPPG 908
Query: 577 ATCFECEITFSNVNNYYVHKRLYC-------SGRRAPEDAPAARRPKAPPGP----ARAP 625
S V L +G + + P P P P ++
Sbjct: 909 PLGIPGR---SGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGE 965
Query: 626 PGQPAEPDAPRSSPGPGAR----EEGAGGAATPEDGAGGRGSEGSQSPGSSVDDAEDDPS 681
G+P P P S G + + G G + G G +G+ PG P
Sbjct: 966 KGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGN--PGLPGQPGLIGPP 1023
Query: 682 RTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRPAAPPGPPG-PAAPPAPSPAAPVRT 740
++ F P P+ PPGP G P P +P
Sbjct: 1024 GLKGTIGDMGF-------------------PGPQGVEGPPGPSGVPGQPGSPGLPGQKGD 1064
Query: 741 RRRRKLYELHAAGAP-PPPPPGHAPAPESP-------------RPGSGSGSG-PGLAPAR 785
+ + + G P P PG P +P PG+ G PGL P
Sbjct: 1065 KGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGL-PGF 1123
Query: 786 SPGPAADGPIDLSKKPRRP-LPGAPAPALADYHECTACRVSFHSLEAYLAHKKYSCPAAP 844
P GP +S P P LPG P P H P P
Sbjct: 1124 PGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHP--------------------GQPGPP 1163
Query: 845 ----PPGALGLPAAACPYCPPNGPVRGDLLE------HFRLAHGLLLGAP----LAGPGV 890
PG G+P A P P G+ + G L G P L GP
Sbjct: 1164 GEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKG 1223
Query: 891 EARTPADRGPSPAPAPAASPQPGSRGPRDGLGPEPQEPPPGPPPSPAAAPEAVPPPPAPP 950
E G P P SP P GP+ GP+ GPP P +P P PP
Sbjct: 1224 EPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQ------GPPGRP-----GLPGPEGPP 1272
Query: 951 SYSDKGVQTPSKGTP 965
G KG P
Sbjct: 1273 GLPGNGGIKGEKGNP 1287
Score = 59.7 bits (143), Expect = 1e-08
Identities = 148/623 (23%), Positives = 179/623 (28%), Gaps = 160/623 (25%)
Query: 375 QPGSKGEIYSPGAGHPATKLPPDSLGSFQQQ-HTALQG-PLASADLGLAPTPS----PGL 428
+ GSKGE PG P + P+ LGS ++ L G P S G P PGL
Sbjct: 939 EKGSKGE---PGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGL 995
Query: 429 DRKALAEATNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILGPGEPGPQAPSR 488
+ G L G PP +I P+ G GP PS
Sbjct: 996 SGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQ-------GVEGPPGPSG 1048
Query: 489 TPS-PRSPAPARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGPDAAPPASEILAKMS 547
P P SP K + P S +PG G G LP Y P +
Sbjct: 1049 VPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGD------ 1102
Query: 548 ELVHSRLQQGAGAGAGGAQTGL--FPGAPKGATCFECEITFSNVNNYYVHKRLYCSGRRA 605
L G Q GL FPG P G
Sbjct: 1103 ----PGLPGLPGTPGAKGQPGLPGFPGTPGPPGP---------------------KGISG 1137
Query: 606 PEDAPAARRPKAPPGPARAP--PGQPAEPDAPRSS--PGPGAREEGAGGAATPEDGAGGR 661
P P P G P PG P E P PGP ++ G G G
Sbjct: 1138 PPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGL 1197
Query: 662 GSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRPAAPP 721
Q + +P + +P
Sbjct: 1198 PGLSGQKGDGGLPGIPGNPGLP-----------------------GPKGEPGFHGFPGVQ 1234
Query: 722 GPPGPAAPPAPSPAAPVRTRRRRKLYELHAAGAPPPP-PPGHA--PAPESPR--PGSGSG 776
GPPGP P P+ P G P P PPG P PE P PG+G
Sbjct: 1235 GPPGPPGSPGPALEGP--------------KGNPGPQGPPGRPGLPGPEGPPGLPGNGGI 1280
Query: 777 SGPGLAPARS-----PGPAAD-GPIDLSKKPRRP----------LPGAPAPALADYHECT 820
G P + PG D GP L P RP LPG P
Sbjct: 1281 KGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPG---------- 1330
Query: 821 ACRVSFHSLEAYLAHKKYSCPAAPP-----PGALGLPAAACPYCPPNGP---VRGDLLEH 872
F ++ + P P PG GLP P+G ++GD
Sbjct: 1331 -----FPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPG-------PSGQSIIIKGDAGPP 1378
Query: 873 FRLAHGLLLGAPLAGPGVEARTPADRGPSPAPA----------------PAASPQPGSRG 916
L G P GP P GP P P QPG+RG
Sbjct: 1379 GIPGQPGLKGLP--GPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRG 1436
Query: 917 PRDGLGPEPQEPPPGPPPSPAAA 939
GP+ + PPGPP + + A
Sbjct: 1437 LDGPPGPDGLQGPPGPPGTSSVA 1459
Score = 54.7 bits (130), Expect = 4e-07
Identities = 172/698 (24%), Positives = 207/698 (29%), Gaps = 152/698 (21%)
Query: 376 PGSKGEIYSPGA-------GHPATKLPPDSLGSFQQQHTALQGPLASADLGLAPTP-SPG 427
PG KGE GA G P P GS + L P D G +P +PG
Sbjct: 511 PGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPG 570
Query: 428 LDRKALAEATNG-EARAEPLAQNGGSS-----EPPAAPRSIKVEAVEEPEAAPILGP--- 478
L +G P + GG + PP P + P P GP
Sbjct: 571 LPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGP 630
Query: 479 -GEPGPQAPSRTPS-PRSPAPARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGPDAA 536
GE G Q + P P P P + + PG +PG G G + LP D
Sbjct: 631 VGEKGIQGVAGNPGQPGIPGPKGDPGQTITQ-PGKPGLPGNPGRDGDVGLPG-----DPG 684
Query: 537 PPASEILAKMSELVHSRLQQGAGAGAGGAQTGLFPG--APKGATCFECEITFSNVNNYYV 594
P L + G G G FPG P GA I
Sbjct: 685 LPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKG-FPGIPGPPGAPGTPGRI---------- 733
Query: 595 HKRLYCSGRRAPEDAPAARRPKAPPGPAR-APPGQPAEPD-----APRSS------PGPG 642
G P P PK PG A PPG P P P+ PGP
Sbjct: 734 -------GLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPP 786
Query: 643 AREEGAGGAATPEDGAGGRGSEGSQSP----GSSVDDAEDDPSRTLCEACNIRFSRHETY 698
R G G P+ G G G P G V P + +
Sbjct: 787 GRT-GLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPG------IPGPIGQPGLH 839
Query: 699 TVHKRYYCASRHDP---------PPRRPAAP--PGPPGPAAPPAPSPAAPVRTRRRR--- 744
+ + DP PP +P PG PGP PP SP P +
Sbjct: 840 GIP-----GEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPG-SPGLPGKAGASGFPG 893
Query: 745 KLYELHAAGAPPPPPPGHAPAPESPRPGSGSGSG----PGLAPARSPGPAADGPIDLSKK 800
E+ G P PP P P S PG G PGL PGP + K
Sbjct: 894 TKGEMGMMGPPGPPGPLGIPG-RSGVPGLKGDDGLQGQPGL-----PGPTGEK----GSK 943
Query: 801 PRRPLPGAPAPALADY--HECTACRVSFHSLEAYLAHKKYSCPAAPP-----PGALGLPA 853
LPG P P + + + K Y P G GLP
Sbjct: 944 GEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPG 1003
Query: 854 AACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGP-GVEARTPADRGPSPAPAPAASPQ- 911
P P P + L+ L G + GP GVE GPS P SP
Sbjct: 1004 PPGPKGNPGLPGQPGLIGPPGLK-GTIGDMGFPGPQGVEGPP----GPSGVPGQPGSPGL 1058
Query: 912 PGSRGPRDGLG---------PEPQEPP--------------------PGPPPSPAAAPE- 941
PG +G + G P P+ P PG P +P A +
Sbjct: 1059 PGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQP 1118
Query: 942 ------AVPPPPAPPSYSDKGVQTPSKGTPAPLPNGNH 973
P PP P S G P P+ G H
Sbjct: 1119 GLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGH 1156
>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
sapiens]
Length = 1688
Score = 81.6 bits (200), Expect = 3e-15
Identities = 139/537 (25%), Positives = 166/537 (30%), Gaps = 115/537 (21%)
Query: 478 PGEPGPQAPSRTPSPRSPAPARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGPDAAP 537
PG PGP + P P + + P +PG GL G P P
Sbjct: 382 PGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGL---PGPPG 438
Query: 538 PASEILAKMSELVHSRLQQGAGA-GAGGAQTGLFPGAPKGATCFECEITFSNVNNYYVHK 596
PA + E+ G+ G G Q KG TCF C T
Sbjct: 439 PAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGT----------- 487
Query: 597 RLYCSGRRAPEDAPAARRPKAPPGP--------------ARAPPGQPAEPDAPRSSPGPG 642
G P P PPG A P G P P AP + PG
Sbjct: 488 -----GISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPG 542
Query: 643 AREEGAGGAATPEDGAGGRGSEGSQS-------PGSSVDDAEDDPSRTLCEACNIRFSRH 695
++ E G T G +G GS PG+ D E I F
Sbjct: 543 SKGE-PGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGE 601
Query: 696 ETYTVHKRYYCASRHDPPPRRPAAP--PGPPGPAAPPAPSPAAPVRTRRRRKLYELHAAG 753
PP P P PG GP PP P PV + + + G
Sbjct: 602 R---------------GPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGV--AGNPG 644
Query: 754 APPPPPPGHAPAPESPRPGSGSGSGPGLAPARSPG-PAADGPIDLSKKPRRP----LPGA 808
P P P P +PG PGL PG P DG + L P P LPG
Sbjct: 645 QPGIPGPKGDPGQTITQPGK-----PGL-----PGNPGRDGDVGLPGDPGLPGQPGLPGI 694
Query: 809 PA----PALADYHECTACRVSFHSLEAYLAHKKYSCPAAP-PPGALGLPAAACPYCPPNG 863
P P + L K + P P PPGA G P PP
Sbjct: 695 PGSKGEPGIPGI-----------GLPGPPGPKGF--PGIPGPPGAPGTPGRIGLEGPPGP 741
Query: 864 P----VRGDLLEHFRLAHGLLLGAPLAGPGVEARTPA-----DRG-PSPAPAPAASPQPG 913
P +G+ G L P PG+ A DRG P P P + G
Sbjct: 742 PGFPGPKGE--------PGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDG 793
Query: 914 SRGPRDGLGPEPQEPPPGPPPSPAAAPEAVPPPPA-PPSYSDKGVQ--TPSKGTPAP 967
GP+ +GP Q P GPP P + P PP P G+ KG P P
Sbjct: 794 LPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGP 850
Score = 71.2 bits (173), Expect = 4e-12
Identities = 159/665 (23%), Positives = 214/665 (32%), Gaps = 124/665 (18%)
Query: 377 GSKGEIYSPGA-------GHPATKLPPDSLGSFQQQHTALQGPLASADL----GLAPTP- 424
G KGE PG G P + PP G Q+ + GP + GL P
Sbjct: 45 GEKGERGFPGLEGHPGLPGFPGPEGPPGPRG--QKGDDGIPGPPGPKGIRGPPGLPGFPG 102
Query: 425 SPGLDRKALAEATNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILGPGEPGPQ 484
+PGL + G G P +P ++ P P + GEPG
Sbjct: 103 TPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGM-KGEPGSI 161
Query: 485 APSRTPSPRS----PAPARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGPDAAPPAS 540
S P P+ P P ++ PG + +PG +G G P + GP P
Sbjct: 162 IMSSLPGPKGNPGYPGPPGIQG-----LPGPTGIPGPIGPPG----PPGLMGPPGPPGLP 212
Query: 541 EILAKMSELVHSRLQQGAGAGAGGAQTGLFPGAPKGATCFE---CEITFSNVNNYYVHKR 597
M L G G Q P P G + ++ F +
Sbjct: 213 GPKGNMG------LNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGL---- 262
Query: 598 LYCSGRRAPEDAPAARRPKAPPGPARAPPGQPAEPDAPRSSPGPGAREEGAGGAATPEDG 657
G R P P R P PPG + G+ EP R PG G P D
Sbjct: 263 ---PGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEP-GKRGKPGKDGENGQPGIPGLPGDP 318
Query: 658 A--------GGRGSEGSQSPGSSVDDAEDDPSR--TLCEACNIRFSRHETYTVHKRYYCA 707
G +G +G P P T+ E NI + +
Sbjct: 319 GYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGF--- 375
Query: 708 SRHDPPPRRPAAPPGPPGPAAPPAPSPAAPVRTRRRRKLYELHAAGAPPPPPPGHAPAPE 767
P + P PGPPG A P P P R + + G P PPG P
Sbjct: 376 ----PGIQGPPGLPGPPGAAVMGPPGP--PGFPGERGQKGDEGPPGISIPGPPGLDGQPG 429
Query: 768 SP-RPGSGSGSGPGLAPAR---SPGPAA--DGPID------------------------L 797
+P PG +GP + P+ PGP P D +
Sbjct: 430 APGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGI 489
Query: 798 SKKPRRP-LPGAPAPALADYHECTACRVSFHSLEAYLAHKKYSCPAAPPPGALGLPAA-A 855
S P +P LPG P P + + F + +K A P G G+P A
Sbjct: 490 SGPPGQPGLPGLPGPPGS---------LGFPGQKG----EKGQAGATGPKGLPGIPGAPG 536
Query: 856 CPYCPPNGPVRGDLLEHFRLAHGL-LLGAPLAGPGVEARTPADRGPSPAPAPAASPQPGS 914
P P + GD+L + LG+P PG+ P G P PG
Sbjct: 537 APGFPGSKGEPGDILTFPGMKGDKGELGSP-GAPGLPG-LPGTPGQDGLPG-----LPGP 589
Query: 915 RGPRDGLGPEPQEPPPGPPPSPAAAPEAVPPPP----APPSYSDKGVQ--TPSKGTPA-P 967
+G G+ + + PPG P P P P P +KG+Q + G P P
Sbjct: 590 KGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIP 649
Query: 968 LPNGN 972
P G+
Sbjct: 650 GPKGD 654
Score = 63.9 bits (154), Expect = 7e-10
Identities = 158/654 (24%), Positives = 195/654 (29%), Gaps = 147/654 (22%)
Query: 376 PGSKGEIYSPGAGHPATKLPPDSLGSFQQQHTALQGPLASADLGLAPTPSPGLDRKALAE 435
PG KG+ PG P PP GS + A + P SPGL KA A
Sbjct: 842 PGEKGDPGPPGLDVPG---PPGERGS---------PGIPGAPGPIGPPGSPGLPGKAGAS 889
Query: 436 A---TNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILG-PGEPGPQAPSRTPS 491
T GE G PP P + + P + + G G+ G Q P
Sbjct: 890 GFPGTKGEM---------GMMGPPGPPGPLGI-----PGRSGVPGLKGDDGLQGQPGLPG 935
Query: 492 PRSPAPARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGPDAAPPASEILAKMSELVH 551
P + K E P P P LG G P P + P +
Sbjct: 936 PTGEKGS--KGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKG----------Y 983
Query: 552 SRLQQGAGAGAGGAQTGL-FPGAPKGATCFECEITFSNVNNYYVHKRLYCSGRRAPEDAP 610
L G Q GL P PKG + G P
Sbjct: 984 QGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGL--------KGTIGDMGFP 1035
Query: 611 AARRPKAPPGPARAP--PGQPAEPDAPRSSPGPGAREEGAGGAATPEDGAGGRGSEGSQS 668
+ + PPGP+ P PG P P PG G G P+ G G G+
Sbjct: 1036 GPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPG 1095
Query: 669 PGSSVDD-----------AEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRP 717
SV D A+ P + + P P+
Sbjct: 1096 IKGSVGDPGLPGLPGTPGAKGQPGLP--------------------GFPGTPGPPGPKGI 1135
Query: 718 AAPPGPPGPAAPPAP-----SPAAPVRTRRRRKLYELHAAGAP----PPPPPGHAPAPES 768
+ PPG PG P P P P + K + G P PG
Sbjct: 1136 SGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPP 1195
Query: 769 PRPGSGSGSGPGLAPARSPGPAADGP--------IDLSKKPRRPLPGAPAPALADYHECT 820
PG G G P P GP + P P PG+P PAL
Sbjct: 1196 GLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGP-PGSPGPALE------ 1248
Query: 821 ACRVSFHSLEAYLAHKKYSCPAAPP--PGALGLPA-AACPYCPPNGPVRGDLLEHFRLAH 877
K P PP PG GLP P P NG ++G E
Sbjct: 1249 -------------GPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKG---EKGNPGQ 1292
Query: 878 GLLLGAP-LAG----PGVEAR--TPADRGPSPAPA-PAASPQPGSRGPR---DGLGPEPQ 926
L G P L G PG++ P G P P PG +GP GPE +
Sbjct: 1293 PGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGE 1352
Query: 927 E---PPPGPPPSPAAAPEAV------PPPPAPPSYSDKGVQTPSKGTPAPLPNG 971
PPGPP P + +++ PP P KG+ P P P G
Sbjct: 1353 PGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTG 1406
Score = 61.2 bits (147), Expect = 5e-09
Identities = 160/675 (23%), Positives = 205/675 (30%), Gaps = 164/675 (24%)
Query: 376 PGSKGEIYSPGAG---------HPATKLPPDSLGSFQQQHTALQGPLA-------SADLG 419
PGSKGE PG G P PP + G+ L+GP + G
Sbjct: 695 PGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGT--PGRIGLEGPPGPPGFPGPKGEPG 752
Query: 420 LA---PTPSPGLDRKALAEATNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPIL 476
A P PGL A G+ G PP P ++ + P+ +
Sbjct: 753 FALPGPPGPPGLPGFKGALGPKGDR---------GFPGPPGPPGRTGLDGLPGPKGD--V 801
Query: 477 GP-GEPGPQAPSRTPS---------PRSPAPAR------VKAELSSPTPGSSPVPGELGL 520
GP G+PGP P P P P P + E P P VPG G
Sbjct: 802 GPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGE 861
Query: 521 AGALFLPQYVFGPDAAPPASEILAKMSELVHSRLQQGAGA----GAGGAQTGLFPGAPKG 576
G+ +P GP P + + K AGA G G + P P G
Sbjct: 862 RGSPGIPGAP-GPIGPPGSPGLPGK------------AGASGFPGTKGEMGMMGPPGPPG 908
Query: 577 ATCFECEITFSNVNNYYVHKRLYC-------SGRRAPEDAPAARRPKAPPGP----ARAP 625
S V L +G + + P P P P ++
Sbjct: 909 PLGIPGR---SGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGE 965
Query: 626 PGQPAEPDAPRSSPGPGAR----EEGAGGAATPEDGAGGRGSEGSQSPGSSVDDAEDDPS 681
G+P P P S G + + G G + G G +G+ PG P
Sbjct: 966 KGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGN--PGLPGQPGLIGPP 1023
Query: 682 RTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRPAAPPGPPG-PAAPPAPSPAAPVRT 740
++ F P P+ PPGP G P P +P
Sbjct: 1024 GLKGTIGDMGF-------------------PGPQGVEGPPGPSGVPGQPGSPGLPGQKGD 1064
Query: 741 RRRRKLYELHAAGAP-PPPPPGHAPAPESP-------------RPGSGSGSG-PGLAPAR 785
+ + + G P P PG P +P PG+ G PGL P
Sbjct: 1065 KGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGL-PGF 1123
Query: 786 SPGPAADGPIDLSKKPRRP-LPGAPAPALADYHECTACRVSFHSLEAYLAHKKYSCPAAP 844
P GP +S P P LPG P P H P P
Sbjct: 1124 PGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHP--------------------GQPGPP 1163
Query: 845 ----PPGALGLPAAACPYCPPNGPVRGDLLE------HFRLAHGLLLGAP----LAGPGV 890
PG G+P A P P G+ + G L G P L GP
Sbjct: 1164 GEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKG 1223
Query: 891 EARTPADRGPSPAPAPAASPQPGSRGPRDGLGPEPQEPPPGPPPSPAAAPEAVPPPPAPP 950
E G P P SP P GP+ GP+ GPP P + +P P PP
Sbjct: 1224 EPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQ------GPPGRPGF--QGLPGPEGPP 1275
Query: 951 SYSDKGVQTPSKGTP 965
G KG P
Sbjct: 1276 GLPGNGGIKGEKGNP 1290
Score = 58.5 bits (140), Expect = 3e-08
Identities = 148/626 (23%), Positives = 179/626 (28%), Gaps = 163/626 (26%)
Query: 375 QPGSKGEIYSPGAGHPATKLPPDSLGSFQQQ-HTALQG-PLASADLGLAPTPS----PGL 428
+ GSKGE PG P + P+ LGS ++ L G P S G P PGL
Sbjct: 939 EKGSKGE---PGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGL 995
Query: 429 DRKALAEATNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILGPGEPGPQAPSR 488
+ G L G PP +I P+ G GP PS
Sbjct: 996 SGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQ-------GVEGPPGPSG 1048
Query: 489 TPS-PRSPAPARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGPDAAPPASEILAKMS 547
P P SP K + P S +PG G G LP Y P +
Sbjct: 1049 VPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGD------ 1102
Query: 548 ELVHSRLQQGAGAGAGGAQTGL--FPGAPKGATCFECEITFSNVNNYYVHKRLYCSGRRA 605
L G Q GL FPG P G
Sbjct: 1103 ----PGLPGLPGTPGAKGQPGLPGFPGTPGPPGP---------------------KGISG 1137
Query: 606 PEDAPAARRPKAPPGPARAP--PGQPAEPDAPRSS--PGPGAREEGAGGAATPEDGAGGR 661
P P P G P PG P E P PGP ++ G G G
Sbjct: 1138 PPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGL 1197
Query: 662 GSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRPAAPP 721
Q + +P + +P
Sbjct: 1198 PGLSGQKGDGGLPGIPGNPGLP-----------------------GPKGEPGFHGFPGVQ 1234
Query: 722 GPPGPAAPPAPSPAAPVRTRRRRKLYELHAAGAPPPP-PPGHA-----PAPESPR--PGS 773
GPPGP P P+ P G P P PPG P PE P PG+
Sbjct: 1235 GPPGPPGSPGPALEGP--------------KGNPGPQGPPGRPGFQGLPGPEGPPGLPGN 1280
Query: 774 GSGSGPGLAPARS-----PGPAAD-GPIDLSKKPRRP----------LPGAPAPALADYH 817
G G P + PG D GP L P RP LPG P
Sbjct: 1281 GGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPG------- 1333
Query: 818 ECTACRVSFHSLEAYLAHKKYSCPAAPP-----PGALGLPAAACPYCPPNGP---VRGDL 869
F ++ + P P PG GLP P+G ++GD
Sbjct: 1334 --------FPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPG-------PSGQSIIIKGDA 1378
Query: 870 LEHFRLAHGLLLGAPLAGPGVEARTPADRGPSPAPA----------------PAASPQPG 913
L G P GP P GP P P QPG
Sbjct: 1379 GPPGIPGQPGLKGLP--GPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPG 1436
Query: 914 SRGPRDGLGPEPQEPPPGPPPSPAAA 939
+RG GP+ + PPGPP + + A
Sbjct: 1437 TRGLDGPPGPDGLQGPPGPPGTSSVA 1462
Score = 54.7 bits (130), Expect = 4e-07
Identities = 172/698 (24%), Positives = 207/698 (29%), Gaps = 152/698 (21%)
Query: 376 PGSKGEIYSPGA-------GHPATKLPPDSLGSFQQQHTALQGPLASADLGLAPTP-SPG 427
PG KGE GA G P P GS + L P D G +P +PG
Sbjct: 511 PGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPG 570
Query: 428 LDRKALAEATNG-EARAEPLAQNGGSS-----EPPAAPRSIKVEAVEEPEAAPILGP--- 478
L +G P + GG + PP P + P P GP
Sbjct: 571 LPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGP 630
Query: 479 -GEPGPQAPSRTPS-PRSPAPARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGPDAA 536
GE G Q + P P P P + + PG +PG G G + LP D
Sbjct: 631 VGEKGIQGVAGNPGQPGIPGPKGDPGQTITQ-PGKPGLPGNPGRDGDVGLPG-----DPG 684
Query: 537 PPASEILAKMSELVHSRLQQGAGAGAGGAQTGLFPG--APKGATCFECEITFSNVNNYYV 594
P L + G G G FPG P GA I
Sbjct: 685 LPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKG-FPGIPGPPGAPGTPGRI---------- 733
Query: 595 HKRLYCSGRRAPEDAPAARRPKAPPGPAR-APPGQPAEPD-----APRSS------PGPG 642
G P P PK PG A PPG P P P+ PGP
Sbjct: 734 -------GLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPP 786
Query: 643 AREEGAGGAATPEDGAGGRGSEGSQSP----GSSVDDAEDDPSRTLCEACNIRFSRHETY 698
R G G P+ G G G P G V P + +
Sbjct: 787 GRT-GLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPG------IPGPIGQPGLH 839
Query: 699 TVHKRYYCASRHDP---------PPRRPAAP--PGPPGPAAPPAPSPAAPVRTRRRR--- 744
+ + DP PP +P PG PGP PP SP P +
Sbjct: 840 GIP-----GEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPG-SPGLPGKAGASGFPG 893
Query: 745 KLYELHAAGAPPPPPPGHAPAPESPRPGSGSGSG----PGLAPARSPGPAADGPIDLSKK 800
E+ G P PP P P S PG G PGL PGP + K
Sbjct: 894 TKGEMGMMGPPGPPGPLGIPG-RSGVPGLKGDDGLQGQPGL-----PGPTGEK----GSK 943
Query: 801 PRRPLPGAPAPALADY--HECTACRVSFHSLEAYLAHKKYSCPAAPP-----PGALGLPA 853
LPG P P + + + K Y P G GLP
Sbjct: 944 GEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPG 1003
Query: 854 AACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGP-GVEARTPADRGPSPAPAPAASPQ- 911
P P P + L+ L G + GP GVE GPS P SP
Sbjct: 1004 PPGPKGNPGLPGQPGLIGPPGLK-GTIGDMGFPGPQGVEGPP----GPSGVPGQPGSPGL 1058
Query: 912 PGSRGPRDGLG---------PEPQEPP--------------------PGPPPSPAAAPE- 941
PG +G + G P P+ P PG P +P A +
Sbjct: 1059 PGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQP 1118
Query: 942 ------AVPPPPAPPSYSDKGVQTPSKGTPAPLPNGNH 973
P PP P S G P P+ G H
Sbjct: 1119 GLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGH 1156
>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
Length = 1838
Score = 80.5 bits (197), Expect = 7e-15
Identities = 176/681 (25%), Positives = 220/681 (32%), Gaps = 167/681 (24%)
Query: 376 PGSKGEIYSPGA-GHPATKLPPDSLGSFQQQHTALQG-PLASADLGLAPTPS-PGLDRKA 432
PG KG++ PG G+P + P S+G G P A+ + G TP PG +
Sbjct: 861 PGEKGKLGVPGLPGYPGRQGPKGSIG--------FPGFPGANGEKGGRGTPGKPGPRGQR 912
Query: 433 LAEATNGEA-----RAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILGPGEPGPQAPS 487
GE +P + + PA P + G GPQ P+
Sbjct: 913 GPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGER---------------GPNGPQGPT 957
Query: 488 RTPSPRSPAPARVKAELSSPTPGSSPVPGELGLAGALFLP--QYVFGPDAAPPASEILAK 545
P P+ P K L PG GE G G P V GP P E
Sbjct: 958 GFPGPKGPPGPPGKDGL----PGHPGQRGETGFQGKTGPPGPPGVVGPQG--PTGET-GP 1010
Query: 546 MSELVHSRL-----QQGAGAGAGGAQTGLFPG--------APKGATCFECEITFSNVNNY 592
M E H +QG AG T PG P G F +
Sbjct: 1011 MGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVG- 1069
Query: 593 YVHKRLYCSGRRAPEDAPAARRPKAPPGPARA--PPGQPAEPDAPRSSPGPGAREEGAGG 650
L G P P GPA A P G P P P+ PGP A E+GA G
Sbjct: 1070 ----ALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRP-GPQGPPGP-AGEKGAPG 1123
Query: 651 AATPEDGAGGRGSEGS---QSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCA 707
P+ AG G +G P V +D + + +
Sbjct: 1124 EKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKG---------------EIGEPGQKG 1168
Query: 708 SRHDPPPRRPAAPPGPPGPAAPPAPSPA-APVRTRRRRKLY----ELHAAGAPPPP---- 758
S+ D + P P GP GP P PS A R ++ L+ + G P PP
Sbjct: 1169 SKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVG 1228
Query: 759 ------PPGHA-----------PAPESPRPGSGS--GSGPGLAPARSPGPAADGPIDLSK 799
PPG P P PR SG+ GP P P A G
Sbjct: 1229 LQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPG 1288
Query: 800 KPRRP-LPGAPAPALADYHECTACRVSFHSLEAYLAHKKYSCP--AAPPPGALGLPAAAC 856
+ P LPG P + K S P AA PPG G P
Sbjct: 1289 EAGEPGLPGEGGPP---------------GPKGERGEKGESGPSGAAGPPGPKGPPGDDG 1333
Query: 857 PYCPPNGPVR--GDLLEHFRLAHGLLLGAP-LAGPGVEARTPADRG----------PSPA 903
P P GPV GD G P GP + P D+G P P
Sbjct: 1334 PKGSP-GPVGFPGDP------------GPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPT 1380
Query: 904 PAPAASPQPGSRGPRDGLGPEPQEPPPG----------PPPSPAAAPEAVPPPPAPPSYS 953
P S PG RGP GPE ++ G P + P+ P P P
Sbjct: 1381 GEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGL- 1439
Query: 954 DKGVQTP--SKGTP-APLPNG 971
+G+ P +G P +P P+G
Sbjct: 1440 -RGIPGPVGEQGLPGSPGPDG 1459
Score = 78.6 bits (192), Expect = 3e-14
Identities = 167/675 (24%), Positives = 195/675 (28%), Gaps = 184/675 (27%)
Query: 377 GSKGEIYSPGA-GHPATKLPPDSLGSFQQQHTALQGPLAS-ADLGLAPTPS----PGLDR 430
G GE G GHP PP G L G + D G A P PGL
Sbjct: 1003 GPTGETGPMGERGHPGPPGPPGEQGL-----PGLAGKEGTKGDPGPAGLPGKDGPPGLRG 1057
Query: 431 KALAEATNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILGPGEPGPQAP---- 486
G A L N G PP P E A PI PG PGPQ P
Sbjct: 1058 FPGDRGLPGPVGALGLKGNEGPPGPPG-PAGSPGERGPAGAAGPIGIPGRPGPQGPPGPA 1116
Query: 487 --SRTPSPRSPAPARVKAELSSPT-----------PGSSPVPGELGLAGALFL------- 526
P + P + L P PG GE+G G
Sbjct: 1117 GEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQ 1176
Query: 527 ----PQYVFGPDAAPPASEILAKMSELVHSRLQQGAGAGAGGAQTGLFPGAP-------- 574
P GP P S + R QQG G FPG P
Sbjct: 1177 GPPGPTGPQGPIGQPGPSGADGEPGP----RGQQGLFGQKGDEGPRGFPGPPGPVGLQGL 1232
Query: 575 ------KGATCFECEITFSNVNNYYVHKRLYCSGRRAPEDAPAARRPKAPPGPARAP--- 625
KG T ++ G R P AP A P+ PPG P
Sbjct: 1233 PGPPGEKGETGDVGQMGPPGP-----------PGPRGPSGAPGADGPQGPPGGIGNPGAV 1281
Query: 626 -----PGQPAEPDAPRSSPGPGAR-EEGAGGAATPEDGAGGRGSEGSQSPGSSVDDAEDD 679
PG+ EP P PG + E G G + P AG G +G PG
Sbjct: 1282 GEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGP--PGDDGPKGSPG 1339
Query: 680 PSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRPAAPPGPPGPAAPPAPSPAAPVR 739
P DP PPG PGPA P P
Sbjct: 1340 P-------------------------VGFPGDP------GPPGEPGPAGQDGP-PGDKGD 1367
Query: 740 TRRRRKLYELHAAGAPPPP-PPGHA--PAPESPRPGSGSGSGPGLAPARSPGPAADGPID 796
+ G P P PPG P P P G G A P P GPI
Sbjct: 1368 DGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGP-PGKTGPIG 1426
Query: 797 LSKKPRRPLP----GAPAPALADYHECTACRVSFHSLEAYLAHKKYSCPAAP----PPGA 848
P +P P G P P + P +P PPG
Sbjct: 1427 PQGAPGKPGPDGLRGIPGPV-----------------------GEQGLPGSPGPDGPPGP 1463
Query: 849 LGLPAAACPYCPPNGP-VRGDLLEHFRLAHGLLLGAPLAGPGVEARTPADRG-------- 899
+G PP P ++GD H L+G L GP E DRG
Sbjct: 1464 MG---------PPGLPGLKGDSGPKGEKGHPGLIG--LIGPPGEQGEKGDRGLPGPQGSS 1512
Query: 900 -------------PSPAPAPAASPQP----GSRGPRDGLGPEPQEPPPGPPPSPAAAPEA 942
P P P P P G++G GP+ + PGPP P E
Sbjct: 1513 GPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPGEV 1572
Query: 943 VPPPPAPPSYSDKGV 957
+ P P S + + +
Sbjct: 1573 IQPLPIQASRTRRNI 1587
Score = 73.2 bits (178), Expect = 1e-12
Identities = 143/602 (23%), Positives = 173/602 (28%), Gaps = 212/602 (35%)
Query: 375 QPGSKGEIYSPGA----GHPATKLPPDSLGSFQQQHTALQGPLAS-ADLGLAPTPSPGLD 429
+ G KGEI PG G + PP G QGP+ G P P
Sbjct: 1154 EDGDKGEIGEPGQKGSKGDKGEQGPPGPTGP--------QGPIGQPGPSGADGEPGPRGQ 1205
Query: 430 RKALAEATNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILGPGEPGPQAPSRT 489
+ + + R P + P K E + + P PG PGP+ PS
Sbjct: 1206 QGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGP---PGPPGPRGPSGA 1262
Query: 490 PSPRSP--APARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGPDAAPPASEILAKMS 547
P P P + PG+ GE G AG LP
Sbjct: 1263 PGADGPQGPPGGI------GNPGAVGEKGEPGEAGEPGLP-------------------- 1296
Query: 548 ELVHSRLQQGAGAGAGGAQTGLFPGAPKGATCFECEITFSNVNNYYVHKRLYCSGRRAPE 607
G GG P PK G R +
Sbjct: 1297 -------------GEGG------PPGPK--------------------------GERGEK 1311
Query: 608 DAPAARRPKAPPGPARAPPGQPAEPDAPRSSPGPGAREEGAGGAATPEDGAGGRGSEGSQ 667
PPGP + PPG D P+ SPGP G G P G G +G
Sbjct: 1312 GESGPSGAAGPPGP-KGPPGD----DGPKGSPGP----VGFPGDPGPPGEPGPAGQDG-- 1360
Query: 668 SPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRPAAPPGPPGPA 727
PG DD E P +T P P P GPPG
Sbjct: 1361 PPGDKGDDGE--PGQT--------------------------GSPGPTGEPGPSGPPGKR 1392
Query: 728 APPAPSPAAPVRTRRRRKLYELHAAGAPPPP----PPGHAPAPESPRPGSGSGSGPGLAP 783
PP P+ + + K AG PP P G AP P P G
Sbjct: 1393 GPPGPAGPEGRQGEKGAK----GEAGLEGPPGKTGPIGPQGAPGKPGPDGLRG------- 1441
Query: 784 ARSPGPAADGPIDLSKKPRRPLPGAPAPALADYHECTACRVSFHSLEAYLAHKKYSCPAA 843
PGP + + LPG+P P
Sbjct: 1442 --IPGPVGE----------QGLPGSPGP-------------------------------D 1458
Query: 844 PPPGALGLPAAACPYCPPNGP-VRGDLLEHFRLAHGLLLGAPLAGPGVEARTPADRG-PS 901
PPG +G PP P ++GD H L+G L GP E DRG P
Sbjct: 1459 GPPGPMG---------PPGLPGLKGDSGPKGEKGHPGLIG--LIGPPGEQGEKGDRGLPG 1507
Query: 902 PAPAPAASPQPGSRGPRDGLGPEPQEPPPGPP-------------PSPAAAPEAVPPPPA 948
P + + G GP +GP PGPP P A P PP
Sbjct: 1508 PQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPG 1567
Query: 949 PP 950
PP
Sbjct: 1568 PP 1569
Score = 68.9 bits (167), Expect = 2e-11
Identities = 181/714 (25%), Positives = 210/714 (29%), Gaps = 211/714 (29%)
Query: 377 GSKGEIYSPGAGHPATKLPPDSLGSFQQQHTALQGPLASADLGLAPTPSPGLDRKALAEA 436
G G + PG+G K P +G Q +QGP P PG +A ++
Sbjct: 568 GRPGPVGPPGSG--GLKGEPGDVGP--QGPRGVQGPPG-------PAGKPGRRGRAGSDG 616
Query: 437 TNG-EARAEPLAQNG-----------------GSSEPPAAPRSIKVEAVEEPEAAPILGP 478
G + P G G S PP P E ++ E P P
Sbjct: 617 ARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGD-DGERGDDGEVGPRGLP 675
Query: 479 GEPGPQ---APSRTPSPRSPAPARVKAELSSPTP-------GSSPVPGELGLAGALFL-- 526
GEPGP+ P P P P P V P P G PG+ G GA L
Sbjct: 676 GEPGPRGLLGPKGPPGP--PGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPG 733
Query: 527 PQYVFGP--DAAPPASEILAKMSELVHSRLQQGAGAGAGGAQTGLFPGAPKGATCFECEI 584
PQ GP + P L M G G G + G P P+G +
Sbjct: 734 PQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGK-EGPPGEKGGQGPPGPQGPIGYPGPR 792
Query: 585 TFSNVNNYYVHK----------------RLYCSGRRAPEDAPAARRPKAP---------- 618
+ K + G R P R P
Sbjct: 793 GVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPN 852
Query: 619 --PGPARAP--------PGQPAEP--DAPRSSPG----PGAREEGAG----------GAA 652
PGP P PG P P P+ S G PGA E G G
Sbjct: 853 GDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQR 912
Query: 653 TPEDGAGGRGSEG-SQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHD 711
P G RG G + PG + D P+
Sbjct: 913 GPTGPRGERGPRGITGKPGPKGNSGGDGPA-----------------------------G 943
Query: 712 PP----PRRPAAPPGPPGPAAPPAP--SPAAPVRTRRRRKLYELHAAGAPPPP------- 758
PP P P P G PGP PP P P +R + G P PP
Sbjct: 944 PPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQG 1003
Query: 759 ------PPGHAPAPESPRPGSGSGSGPGLAPAR----SPGPAA----DGPIDLSKKP-RR 803
P G P P P G PGLA PGPA DGP L P R
Sbjct: 1004 PTGETGPMGERGHPGPPGPPGEQGL-PGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDR 1062
Query: 804 PLPGAPAPALADYHECTACRVSFHSLEAYLAHKKYSCPAAPPPGALGLPAAACPYCPPNG 863
LPG P GALGL P PP G
Sbjct: 1063 GLPG-------------------------------------PVGALGLKGNEGPPGPP-G 1084
Query: 864 PVRGDLLEHFRLAHGLLLGAPLAGP-GVEARTPADRGPSPAPAPAASPQPGSRGP--RDG 920
P + G A AGP G+ R P PA A + G +GP RDG
Sbjct: 1085 PAG---------SPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDG 1135
Query: 921 L-GPEPQEPPPGP--PPSPAAAPEAVPPPPAPPSYSDKGVQTPSKGTPAPLPNG 971
L GP P GP PP + P S DKG Q P T P G
Sbjct: 1136 LQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIG 1189
Score = 65.9 bits (159), Expect = 2e-10
Identities = 141/558 (25%), Positives = 175/558 (31%), Gaps = 140/558 (25%)
Query: 459 PRSIKVEAVEEPEAAP-ILGPGEPGPQAPSRTPSPRSPAPARVKAELSSP----TPGSSP 513
PR K + E P +L G PGP+ P+ P P P ++ P PG
Sbjct: 448 PRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGP--PGTMGPTGQVGDPGERGPPGRPG 505
Query: 514 VPGELGLAG----ALFLP-QYVFGPDAAPPASEILAKMSE----LVHSRLQQGAGAGAGG 564
+PG GL G L LP ++ G DA + A+ S+ L +RL AG G
Sbjct: 506 LPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMG 565
Query: 565 AQTGLFPGAPKGATCFECEITFSNVNNYYVHKRLYCSGRRAPEDAPAARRPKAPPGPARA 624
P P G+ + E G P+ R + PPGPA
Sbjct: 566 LTGRPGPVGPPGSGGLKGE-----------------PGDVGPQ---GPRGVQGPPGPAGK 605
Query: 625 PPGQ-PAEPDAPRSSPGPGA--REEGAGGAATPEDGAGGRGSEG-SQSPGSSVDDAEDDP 680
P + A D R PG + G G A G RG G S PG DD E
Sbjct: 606 PGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGE--- 662
Query: 681 SRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRPAAPPGPPGPAAPPA-------PS 733
R + V R +P PR P GPPGP PP P
Sbjct: 663 -------------RGDDGEVGPR---GLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPG 706
Query: 734 PAAPVRTRRRRKLYELHAAGAP-PPPPPGHAPAPESPRPGSGSGSGPGLAPARSPG---- 788
P V + G P PP G+ A P P G P PG
Sbjct: 707 PKGNVGPQ-----------GEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGM 755
Query: 789 PAADGPIDLSKKPRRPLPGAPAPALADYHECTACRVSFHSLEAYLAHKKYSCPAAPPPGA 848
P ADGP PG P E K P P G
Sbjct: 756 PGADGP-----------PGHPGK------------------EGPPGEKGGQGPPG-PQGP 785
Query: 849 LGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGPGVEARTPADRGPSPAPAPAA 908
+G P P G D + + G G + DRG P P
Sbjct: 786 IGYPG-------PRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRG 838
Query: 909 SPQPGSRGPRDGLGPEPQEPPPGPP--------------PSPAAAPEAVPPPPAPPSYSD 954
+ G GP+ GP P GPP P ++ P P + +
Sbjct: 839 --EDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGE 896
Query: 955 KGVQTPSKGTPA-PLPNG 971
KG +GTP P P G
Sbjct: 897 KG----GRGTPGKPGPRG 910
Score = 64.7 bits (156), Expect = 4e-10
Identities = 156/660 (23%), Positives = 207/660 (31%), Gaps = 124/660 (18%)
Query: 377 GSKGEIYSPGA-GHPATKLPPDSLGSFQQQHTALQGPLASADLGLAPTPSPGLD-RKALA 434
G G++ PG G P P + G T L P G A + P + +++ A
Sbjct: 487 GPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQA 546
Query: 435 EATNGEARAEPLAQNGGSSEPPAAPRSI--KVEAVEEPEAAPILG-PGEPGPQAPSRTPS 491
+A +AR LA G PA P + + V P + + G PG+ GPQ P
Sbjct: 547 QAILQQAR---LALRG-----PAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQG 598
Query: 492 PRSPA-----PARVKAELSSPTPGSSPVPGELGLAGALFLP--------QYVFGPDAAPP 538
P PA R ++ + PG + G+ G G LP GP P
Sbjct: 599 PPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPG 658
Query: 539 ASEILAKMSELVHSRLQQGAG-AGAGGAQTGLFPGAPKGATCFECEI-TFSNVNNYYVHK 596
E+ L G G G + P P G T + + NV
Sbjct: 659 DDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPG 718
Query: 597 RLYCSGRRAPEDAPAARRPKAPPGPARAPPGQPAEPDAPRSSPGPG-------AREEGAG 649
G + P + PPG + P G+P P P + PG E+G
Sbjct: 719 PPGQQGNPGAQGLPGPQGAIGPPG-EKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQ 777
Query: 650 GAATPE------DGAGGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKR 703
G P+ G +G++G + + + +D I+ R E R
Sbjct: 778 GPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPR 837
Query: 704 YYCASRHDPP--PRRPAAPPGPPGPAAPPAPS--------PAAPVRTRRRRKL------- 746
D P P+ P G PGP PP P P R + +
Sbjct: 838 -----GEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPG 892
Query: 747 --YELHAAGAPPPPPPGHAPAPESPR--------------PGSGSGSGPGLAPARSPGPA 790
E G P P P P PR G+ G GP P
Sbjct: 893 ANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNG 952
Query: 791 ADGPIDLSKKPRRPLPGAPAPALADYHECTACRVSFHSLEAYLAHKKYSCPAAPPPGALG 850
GP P+ P PG P H F K P PPG +G
Sbjct: 953 PQGPTGF-PGPKGP-PGPPGKDGLPGHPGQRGETGFQG--------KTGPPG--PPGVVG 1000
Query: 851 LPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAP--LAGPGVEARTPADRGPSPAPAPAA 908
P GP G+ H G P PG+ + P PA P
Sbjct: 1001 ----------PQGPT-GETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGK 1049
Query: 909 SPQPGSR---------GPRDGLGPEPQEPPPGPP----------PSPAAAPEAVPPPPAP 949
PG R GP LG + E PPGPP P+ AA P +P P P
Sbjct: 1050 DGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGP 1109
Score = 47.0 bits (110), Expect = 9e-05
Identities = 116/531 (21%), Positives = 155/531 (29%), Gaps = 135/531 (25%)
Query: 465 EAVEEPEAAPILGPGEPGPQAPSRTPSPRSPAPARVKAELSSPTPGSSPVPGELGLAGAL 524
E E P+ G G P + + T + +PAP P G+ + GE
Sbjct: 359 EGEENPDQPTDPGAGAEIPTSTADTSNSSNPAPP--------PGEGADDLEGEFTEETIR 410
Query: 525 FLPQYVFGPDAAPPASEILAKMSELVHSRLQQGAGAGAGGAQTGLFPGAPKGATCFECEI 584
L + + P P +S S + G A G+ G P+G + E
Sbjct: 411 NLDENYYDPYYDPTSSP----------SEIGPGMPANQDTIYEGI--GGPRGEKGQKGEP 458
Query: 585 TFSNVNNYYVHKRLYCSGRRAPEDAPAARRPKAPPGPA--------RAPPGQPAEPDAPR 636
+ + G PE P GP R PPG+P P A
Sbjct: 459 AI-------IEPGMLIEGPPGPEGPAGLPGPPGTMGPTGQVGDPGERGPPGRPGLPGAD- 510
Query: 637 SSPGPGAREEGAGGAATPEDGAGGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHE 696
PGP G GG G GS+ P S A++ ++ + + +
Sbjct: 511 GLPGP------PGTMLMLPFRFGGGGDAGSKGPMVS---AQESQAQAILQQARLALRG-- 559
Query: 697 TYTVHKRYYCASRHDPPPRRPAAPPGPPGPAAPPA-------PSPAAPVRTRRRRKLYEL 749
P P G PGP PP P P R
Sbjct: 560 -----------------PAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPR-------- 594
Query: 750 HAAGAPPPPPPGHAPAPESPRPGSGSGSGPGLAPARSPGPAADGPID-----LSKKPRRP 804
G PP P P G+ PG GP D D +K R
Sbjct: 595 ---GVQGPPGPAGKPGRRGRAGSDGARGMPG-----QTGPKGDRGFDGLAGLPGEKGHRG 646
Query: 805 LPGA---PAPALADYHECTACRVSFHSLEAYLAHKKYSCPAAPP-----PGALGLPAAAC 856
PG P P D V L + P PP PG G+
Sbjct: 647 DPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPG 706
Query: 857 PYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGPGVEARTPADRGPSPAPAPAASPQPGSRG 916
P +G++ GP E P +G P A P G
Sbjct: 707 P--------KGNV-----------------GPQGEPGPPGQQGN-----PGAQGLP---G 733
Query: 917 PRDGLGPEPQEPPPGPPPSPAAAPEAVPPPPAPPSYSDKGVQTPSKGTPAP 967
P+ +GP ++ P G P P P A PP P G + +G P P
Sbjct: 734 PQGAIGPPGEKGPLGKPGLP-GMPGADGPPGHPGKEGPPG-EKGGQGPPGP 782
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 79.0 bits (193), Expect = 2e-14
Identities = 94/392 (23%), Positives = 120/392 (30%), Gaps = 79/392 (20%)
Query: 606 PEDAPAARRPKAPPGPARAPP--------GQPAEPDAPRSSPGPGAREEGAGGAATPEDG 657
P+ + P +PPG + PP G P P P+ P G + G
Sbjct: 41 PQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG 100
Query: 658 AGGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRP 717
+G + S+SP S + P + + PPP +P
Sbjct: 101 PPPQGDK-SRSPRSPPGKPQGPPPQGGNQP--------------------QGPPPPPGKP 139
Query: 718 AAPP--------GPPGPAAPPAPSPAAPVRTRRRRKLYELHAAGAPPPPPPGHAPAPESP 769
PP GPP P P P P ++R R G P PPP P+ P
Sbjct: 140 QGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRS-----PPGKPQGPPPQGGNQPQGP 194
Query: 770 RPGSGSGSGP---------GLAPARSP-GPAADGPIDLSKKPRRP--LPGAPAPALADYH 817
P G GP G P P GP G + S+ R P P P P +
Sbjct: 195 PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGD-NKSQSARSPPGKPQGPPPQGGNQP 253
Query: 818 ECTACRVSFHSLEAYLAHKKYSCPAAPPPGALGLPAAACPYCPPNGPVR--GDLLEHFRL 875
+ P PPP P P P GP G R
Sbjct: 254 QGPP--------------PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRS 299
Query: 876 AHGLLLGAPLAGPGVEARTPADRGPSPAPAPAASPQPGSRGPRDGLGPEPQEPPPGPPPS 935
G G P G +GP P P P P +G GP P P GPPP
Sbjct: 300 PPGKPQGPPPQGGN------QPQGPPPPPGKPQGPPP--QGGNKPQGPPPPGKPQGPPPQ 351
Query: 936 PAAAPEAVPPPPAPPSYSDKGVQTPSKGTPAP 967
+ + PP P + +G P P
Sbjct: 352 GGSKSRSARSPPGKPQGPPQQEGNNPQGPPPP 383
Score = 69.3 bits (168), Expect = 2e-11
Identities = 82/367 (22%), Positives = 111/367 (30%), Gaps = 76/367 (20%)
Query: 606 PEDAPAARRPKAPPGPARAPP--------GQPAEPDAPRSSPGPGAREEGAGGAATPEDG 657
P +R P++PPG + PP G P P P+ P G + G
Sbjct: 102 PPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG 161
Query: 658 AGGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRP 717
+G S+S S + P + + PPP +P
Sbjct: 162 PPPQGDNKSRSSRSPPGKPQGPPPQGGNQP--------------------QGPPPPPGKP 201
Query: 718 AAPP--------GPPGPAAPPAPSPAAPVRTRRRRKLYELHAAGAPPPPPPGHAPAPESP 769
PP GPP P P P P +++ R G P PPP P+ P
Sbjct: 202 QGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARS-----PPGKPQGPPPQGGNQPQGP 256
Query: 770 RPGSGSGSGPGLAPARSP-GPAADGPIDLSKKPRRPLPGAPAPALADYHECTACRVSFHS 828
P G GP P GP G KP+ P P + + +
Sbjct: 257 PPPPGKPQGPPPQGGNKPQGPPPPG------KPQGPPPQGGSKSRS-------------- 296
Query: 829 LEAYLAHKKYSCPAAPPPGALGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGP 888
+ P PPP P P P G +G + G GP
Sbjct: 297 -----SRSPPGKPQGPPPQGGNQPQGPPP---PPGKPQGPPPQGGNKPQGPPPPGKPQGP 348
Query: 889 GVEARTPADRGPSPAPAPAASPQPGSRGPRD-----GLGPEP-QEPPPGPPPSPAAAPEA 942
+ + + SP P PQ P+ G P+ Q PP G P P P+
Sbjct: 349 PPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQG 408
Query: 943 VPPPPAP 949
P P
Sbjct: 409 GRPSRPP 415
Score = 68.6 bits (166), Expect = 3e-11
Identities = 75/276 (27%), Positives = 91/276 (32%), Gaps = 56/276 (20%)
Query: 713 PPR---RPAAPPGPPG-PAAPPAPSPAAPVRTRRRRKLYELHAAGAPPPPPPGHAPAPES 768
PP+ +P PP PPG P PP P PPPPPG P+
Sbjct: 40 PPQGGNKPQGPPSPPGKPQGPPPQGGNQP----------------QGPPPPPGK---PQG 80
Query: 769 PRPGSGSGSGPGLAPARSPGPAADGPIDLSKKPRRP--LPGAPAPALADYHECTACRVSF 826
P P G+ P + GP G D S+ PR P P P P + +
Sbjct: 81 PPPQGGNKPQGPPPPGKPQGPPPQG--DKSRSPRSPPGKPQGPPPQGGNQPQGPP----- 133
Query: 827 HSLEAYLAHKKYSCPAAPPPGALGLPAAACPYCPPNGPV-RGDLLEHFRLAHGLLLGAPL 885
P PPP P P P GP +GD + G P
Sbjct: 134 ---------PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPP---GKPQ 181
Query: 886 AGPGVEARTPADRGPSPAPAPAASPQPGSRGPRDGLGPEPQEPPPGPPP------SPAAA 939
P P +GP P P P P +G GP P P GPPP A +
Sbjct: 182 GPPPQGGNQP--QGPPPPPGKPQGPPP--QGGNKPQGPPPPGKPQGPPPQGDNKSQSARS 237
Query: 940 PEAVPPPPAPPSYSDKGVQTPSKGTP-APLPNGNHR 974
P P P P + P G P P P G ++
Sbjct: 238 PPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK 273
Score = 62.4 bits (150), Expect = 2e-09
Identities = 93/400 (23%), Positives = 127/400 (31%), Gaps = 91/400 (22%)
Query: 448 QNGGSSEPPAAPRSIKVEAVEEPEAAPILGPGEPGPQAPSRTPSPRSPAPARVKA----- 502
Q G PP P+ + +P+ P G + P ++ SPRSP P + +
Sbjct: 67 QPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSP-PGKPQGPPPQG 125
Query: 503 ----ELSSPTPGSSPVPGELGLAGALFLPQYVFGPDAAPPASEILAKMSELVHSRLQ--- 555
+ P PG P G P P PP + ++ S + Q
Sbjct: 126 GNQPQGPPPPPGKPQGPPPQG-GNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPP 184
Query: 556 -QGAGAGAGGAQTGLFPGAPKGATCFECEITFSNVNNYYVHKRLYCSGRRAPEDAPAARR 614
QG G PG P+G G P+ P +
Sbjct: 185 PQGGNQPQGPPPP---PGKPQGPPP---------------------QGGNKPQGPPPPGK 220
Query: 615 PKAPP-------GPARAPPGQPAEP-----DAPRSSPGPGAREEGAGGAATPEDGAGGRG 662
P+ PP AR+PPG+P P + P+ P P + +G P+ GG
Sbjct: 221 PQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQG----PPPQ---GGNK 273
Query: 663 SEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRH----DPPPRRPA 718
+G PG S++ R SR PPP +P
Sbjct: 274 PQGPPPPGKPQGPPPQGGSKS-------RSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 326
Query: 719 APP--------GPPGPAAPPAPSPAAPVRTRRRRKLYELHAAGAPPPPPPGHAPAPESPR 770
PP GPP P P P P ++R R G P PP P+ P
Sbjct: 327 GPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARS-----PPGKPQGPPQQEGNNPQGPP 381
Query: 771 PGSGSGSGPGLAPARSPGPAADGPIDLSKKPRRPLPGAPA 810
P +G G P P GP PR P G P+
Sbjct: 382 PPAG---GNPQQPQAPPAGQPQGP------PRPPQGGRPS 412
Score = 47.8 bits (112), Expect = 5e-05
Identities = 33/99 (33%), Positives = 42/99 (42%), Gaps = 15/99 (15%)
Query: 879 LLLGAPLAGPGVEARTPADRGPSPAPAPAASPQPGSRGPRDGLGPEPQEPPP------GP 932
L+ G P P P +GP P+P PQ GP G +PQ PPP GP
Sbjct: 31 LIAGNPQGAPPQGGNKP--QGP---PSPPGKPQ----GPPPQGGNQPQGPPPPPGKPQGP 81
Query: 933 PPSPAAAPEAVPPPPAPPSYSDKGVQTPSKGTPAPLPNG 971
PP P+ PPP P +G ++ S +P P G
Sbjct: 82 PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQG 120
Score = 35.0 bits (79), Expect = 0.35
Identities = 29/88 (32%), Positives = 32/88 (36%), Gaps = 13/88 (14%)
Query: 888 PGVEARTPADRGPSPAPAPAASPQPGSRGPRDGLGPEPQ--EPPPGPPPSPAAAPEAVPP 945
P + A P P P P P P GP PQ P GPPP P P
Sbjct: 29 PSLIAGNPQGAPPQGGNKPQGPPSP----PGKPQGPPPQGGNQPQGPPPPPGK-----PQ 79
Query: 946 PPAPPSYSDKGVQTPSKGTP-APLPNGN 972
P PP +K P G P P P G+
Sbjct: 80 GP-PPQGGNKPQGPPPPGKPQGPPPQGD 106
Score = 35.0 bits (79), Expect = 0.35
Identities = 21/61 (34%), Positives = 24/61 (39%), Gaps = 9/61 (14%)
Query: 43 PSPPSADVNSPP--------PLPPPTSPGGPKELEGQEPE-PRPTEEEPGSPWSGPDELE 93
PSPP PP P PPP P GP G +P+ P P + G P G
Sbjct: 51 PSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRS 110
Query: 94 P 94
P
Sbjct: 111 P 111
Score = 35.0 bits (79), Expect = 0.35
Identities = 20/64 (31%), Positives = 24/64 (37%), Gaps = 9/64 (14%)
Query: 35 QKATAPEAPSPPSADVNSPP-------PLPPPTSPGGPKELEGQEPEPRPTEEEPGSPWS 87
Q P+ P PP PP P PP P GP G +P+ P PG P
Sbjct: 84 QGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPP--PPPGKPQG 141
Query: 88 GPDE 91
P +
Sbjct: 142 PPPQ 145
Score = 35.0 bits (79), Expect = 0.35
Identities = 20/65 (30%), Positives = 24/65 (36%), Gaps = 10/65 (15%)
Query: 35 QKATAPEAPSPPSADVNSPPPL--------PPPTSPGGPKELEGQEPEPRPTEEEPGSPW 86
Q P+ P PP PPP PPP P GP G + R + PG P
Sbjct: 248 QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGS--KSRSSRSPPGKPQ 305
Query: 87 SGPDE 91
P +
Sbjct: 306 GPPPQ 310
Score = 35.0 bits (79), Expect = 0.35
Identities = 20/65 (30%), Positives = 23/65 (35%), Gaps = 10/65 (15%)
Query: 35 QKATAPEAPSPPSADVNSPPPL--------PPPTSPGGPKELEGQEPEPRPTEEEPGSPW 86
Q P+ P PP PPP PPP P GP G + R PG P
Sbjct: 310 QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGS--KSRSARSPPGKPQ 367
Query: 87 SGPDE 91
P +
Sbjct: 368 GPPQQ 372
Score = 34.7 bits (78), Expect = 0.46
Identities = 26/95 (27%), Positives = 35/95 (36%), Gaps = 11/95 (11%)
Query: 40 PEAPSPPSADVNSPPPLPPPTSPGGPKELEGQEPEPRPTEEEPGSPWSGPDELEPVVQDG 99
P+ P P + PP PPP P GP G +P+ P PG P P + G
Sbjct: 118 PQGPPPQGGNQPQGPP-PPPGKPQGPPPQGGNKPQGPP---PPGKPQGPPPQ-------G 166
Query: 100 QRRIRARLSLATGLSWGPFHGSVQTRASSPRQAEP 134
+ R+ S P G Q + P +P
Sbjct: 167 DNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKP 201
Score = 34.7 bits (78), Expect = 0.46
Identities = 23/83 (27%), Positives = 31/83 (37%), Gaps = 13/83 (15%)
Query: 35 QKATAPEAPSPPSADVNSPPP--------LPPPTSPGGPKELEGQEPEPRP-----TEEE 81
Q P+ P PP PP PP P GP + EG P+ P ++
Sbjct: 331 QGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQ 390
Query: 82 PGSPWSGPDELEPVVQDGQRRIR 104
P +P +G + P G R R
Sbjct: 391 PQAPPAGQPQGPPRPPQGGRPSR 413
Score = 34.3 bits (77), Expect = 0.61
Identities = 20/65 (30%), Positives = 23/65 (35%), Gaps = 11/65 (16%)
Query: 35 QKATAPEAPSPPSADVNSPPPL--------PPPTSPGGPKELEGQEPEPRPTEEEPGSPW 86
Q P+ P PP PPP PPP P GP + PR PG P
Sbjct: 63 QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPR---SPPGKPQ 119
Query: 87 SGPDE 91
P +
Sbjct: 120 GPPPQ 124
Score = 34.3 bits (77), Expect = 0.61
Identities = 16/46 (34%), Positives = 21/46 (45%), Gaps = 1/46 (2%)
Query: 40 PEAPSPPSADVNSPPPLPPPTSPGGPKELEGQEPEPRPTEEEPGSP 85
P+ P P + PP PPP P GP G +P+ P +P P
Sbjct: 180 PQGPPPQGGNQPQGPP-PPPGKPQGPPPQGGNKPQGPPPPGKPQGP 224
Score = 34.3 bits (77), Expect = 0.61
Identities = 16/46 (34%), Positives = 21/46 (45%), Gaps = 1/46 (2%)
Query: 40 PEAPSPPSADVNSPPPLPPPTSPGGPKELEGQEPEPRPTEEEPGSP 85
P+ P P + PP PPP P GP G +P+ P +P P
Sbjct: 242 PQGPPPQGGNQPQGPP-PPPGKPQGPPPQGGNKPQGPPPPGKPQGP 286
Score = 34.3 bits (77), Expect = 0.61
Identities = 16/46 (34%), Positives = 21/46 (45%), Gaps = 1/46 (2%)
Query: 40 PEAPSPPSADVNSPPPLPPPTSPGGPKELEGQEPEPRPTEEEPGSP 85
P+ P P + PP PPP P GP G +P+ P +P P
Sbjct: 304 PQGPPPQGGNQPQGPP-PPPGKPQGPPPQGGNKPQGPPPPGKPQGP 348
Score = 33.1 bits (74), Expect = 1.3
Identities = 20/65 (30%), Positives = 26/65 (40%), Gaps = 10/65 (15%)
Query: 35 QKATAPEAPSPPSADVNSPPPL--------PPPTSPGGPKELEGQEPEPRPTEEEPGSPW 86
Q P+ P PP PPP PPP P GP +G + + R + PG P
Sbjct: 124 QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPP-QG-DNKSRSSRSPPGKPQ 181
Query: 87 SGPDE 91
P +
Sbjct: 182 GPPPQ 186
Score = 32.3 bits (72), Expect = 2.3
Identities = 18/52 (34%), Positives = 22/52 (42%), Gaps = 3/52 (5%)
Query: 40 PEAPSPPSADVNSPPPLPPPTSPGGPKELEGQEPEPRPTEEEPGSPWSGPDE 91
P+ P PP D S PP P GP G +P+ P PG P P +
Sbjct: 221 PQGP-PPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPP--PPPGKPQGPPPQ 269
Score = 31.6 bits (70), Expect = 3.9
Identities = 19/65 (29%), Positives = 23/65 (35%), Gaps = 10/65 (15%)
Query: 35 QKATAPEAPSPPSADVNSPPP--------LPPPTSPGGPKELEGQEPEPRPTEEEPGSPW 86
Q P+ P PP PP PP P GP G +P+ P PG P
Sbjct: 269 QGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPP--PPPGKPQ 326
Query: 87 SGPDE 91
P +
Sbjct: 327 GPPPQ 331
Score = 31.2 bits (69), Expect = 5.1
Identities = 19/65 (29%), Positives = 25/65 (38%), Gaps = 10/65 (15%)
Query: 35 QKATAPEAPSPPSADVNSPPPL--------PPPTSPGGPKELEGQEPEPRPTEEEPGSPW 86
Q P+ P PP PPP PPP P GP +G + + + PG P
Sbjct: 186 QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPP-QG-DNKSQSARSPPGKPQ 243
Query: 87 SGPDE 91
P +
Sbjct: 244 GPPPQ 248
Score = 30.8 bits (68), Expect = 6.7
Identities = 20/74 (27%), Positives = 28/74 (37%), Gaps = 11/74 (14%)
Query: 27 LVGASHMEQKATAPEAPS---------PPSADVNSPPPLPPPTSPGGPKELEGQEPEPRP 77
L A ++ + + E+PS PP P PP P GP G +P+ P
Sbjct: 13 LSSAQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPP 72
Query: 78 TEEEPGSPWSGPDE 91
PG P P +
Sbjct: 73 --PPPGKPQGPPPQ 84
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 78.2 bits (191), Expect = 4e-14
Identities = 74/240 (30%), Positives = 82/240 (34%), Gaps = 57/240 (23%)
Query: 759 PPGHAPAPESPRPGSGSGSGPGLAPA--RSPGPAADG----PIDLSKKPRRPLPGAPAPA 812
PPG + P+ G G G PG P R PGPA G P + P RP G P P
Sbjct: 188 PPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGPP 247
Query: 813 LADYHECTACRVSFHSLEAYLAHKKYSCPAAPPPGALGLPAAACPYCPPNGPVRGDLLEH 872
P PPPG + P A P P RGD
Sbjct: 248 --------------------------GPPGPPPPGQVLPPPLAGP------PNRGDRPPP 275
Query: 873 FRLAHGLLLGAPLAGP-------------GVEARTPADRGPSPAPAPAASPQPGSRGPRD 919
L G G P GP P +GP P P P PG GP
Sbjct: 276 PVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPL 335
Query: 920 GLGPEPQ--EPPPG-PPPSPAAAPEAVPPPP---APPSYSDKGVQTPSKGTPAPLPNGNH 973
L P P PPPG PPP+P P PPP P S S T G P P G++
Sbjct: 336 TLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDY 395
Score = 73.6 bits (179), Expect = 9e-13
Identities = 57/172 (33%), Positives = 64/172 (37%), Gaps = 44/172 (25%)
Query: 713 PPRRPAAPPGPPGPAAPPAPS-----PAAPVRTRRRRKLYELHAAG-------------A 754
PPR P PPGPPGP PP P P A R R + G
Sbjct: 236 PPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPG 295
Query: 755 PPPPPPGHAPAPESPRPGSGSGSGPGLAPARSPGPAADGPIDLSKKPR--RPLPGAPAPA 812
PPPP PG+ P P P P G PG P R PGP P+ L+ P P PGAP PA
Sbjct: 296 PPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGP-PLTLAPPPHLPGPPPGAPPPA 354
Query: 813 LADYHECTACRVSFHSLEAYLAHKKYSCPAAPPPGALGLPAAACPYCPPNGP 864
H A+ PPP G+P + PP P
Sbjct: 355 P-------------HVNPAFF----------PPPTNSGMPTSDSRGPPPTDP 383
Score = 72.4 bits (176), Expect = 2e-12
Identities = 71/220 (32%), Positives = 77/220 (35%), Gaps = 54/220 (24%)
Query: 721 PGPPGPAAPPAPSPAAPVRTRRRRKLYELHAAGAPPPPPPGHA-PAPESPRPGSGSGSGP 779
PGP GP PP P PA +T R L G P PPPPG P P + P G P
Sbjct: 218 PGPAGPGGPPPPFPAG--QTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPP 275
Query: 780 GLAPARSPGPAADGPIDLSKKPRRPLPGAPAPALADYHECTACRVSFHSLEAYLAHKKYS 839
P PG P P PLP P P + Y
Sbjct: 276 ---PVLFPGQPFGQP------PLGPLPPGPPPPVPG----------------------YG 304
Query: 840 CPAAPPPGALGLPAAACPYCP-PNGPVRGDLLEHFRLAHGLLLGAPLAGPGVEARTPADR 898
P PPP G P P+ P P GP L L L P PG P
Sbjct: 305 PPPGPPPPQQGPPPPPGPFPPRPPGP----------LGPPLTLAPPPHLPG-----PPPG 349
Query: 899 GPSPAP--APAASPQPGSRG--PRDGLGPEPQEPPPGPPP 934
P PAP PA P P + G D GP P +P PPP
Sbjct: 350 APPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPP 389
Score = 46.6 bits (109), Expect = 1e-04
Identities = 64/251 (25%), Positives = 72/251 (28%), Gaps = 63/251 (25%)
Query: 563 GGAQTGLFPGAPKGATCFECEITFSNVNNYYVHKRLYCSGRRAPEDAPAARRPKAPPGPA 622
GG G FPGA G F P PA + P PP
Sbjct: 200 GGRGRGRFPGAVPGGDRFPGP----------------AGPGGPPPPFPAGQTPPRPPLGP 243
Query: 623 RAPPGQPAEPDAPRSSPGPGAREEGAGGAATPEDGAGGRGSEGSQSPGSSVDDAEDDPSR 682
PPG P P + P P A G P G Q P + P
Sbjct: 244 PGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPP--VLFPGQPFGQPPLGPLPPGPPPP-- 299
Query: 683 TLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRPAAPPGPPGPAAPPAPSPAAPVRTRR 742
+ PPP P GPP P P P P P+
Sbjct: 300 ------------------------VPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGP-- 333
Query: 743 RRKLYELHAAGAPPPPPPGHAPAPESPRPGSGSGSGPGLAPARSPGPAADG-PIDLSKKP 801
APPP PG P P +P P P + PA P P G P S+ P
Sbjct: 334 -------PLTLAPPPHLPG--PPPGAPPP------APHVNPAFFPPPTNSGMPTSDSRGP 378
Query: 802 RRPLP-GAPAP 811
P G P P
Sbjct: 379 PPTDPYGRPPP 389
Score = 38.5 bits (88), Expect = 0.032
Identities = 48/164 (29%), Positives = 56/164 (34%), Gaps = 30/164 (18%)
Query: 385 PGAGHPATKLPPDSLGSFQQQHTALQGPLASADLGLAPTPSPGLDRKALAEATNGEARAE 444
PG P PP F T + PL P P P G+
Sbjct: 218 PGPAGPGGPPPP-----FPAGQTPPRPPLGPPGPPGPPGPPPP-----------GQVLPP 261
Query: 445 PLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILGPGEPG--PQAPSRTPSPRSPAPARVKA 502
PLA + P P V +P P LGP PG P P P P P P
Sbjct: 262 PLAGPPNRGDRPPPP----VLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPP----Q 313
Query: 503 ELSSPTPGSSP--VPGELGLAGALFLPQYVFG--PDAAPPASEI 542
+ P PG P PG LG L P ++ G P A PPA +
Sbjct: 314 QGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHV 357
Score = 35.8 bits (81), Expect = 0.21
Identities = 30/85 (35%), Positives = 33/85 (38%), Gaps = 11/85 (12%)
Query: 899 GPSPAPAPAASPQPG-SRG------PRDGLGPEPQEPPPGPPPSPAAAPEAVPP--PPAP 949
GP + AA PQ G RG P P P P PPP PA PP PP P
Sbjct: 187 GPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGP 246
Query: 950 PSYSDKGVQTPSKGTPAPLPNGNHR 974
P G P + P PL +R
Sbjct: 247 P--GPPGPPPPGQVLPPPLAGPPNR 269
Score = 34.3 bits (77), Expect = 0.61
Identities = 22/58 (37%), Positives = 24/58 (41%), Gaps = 9/58 (15%)
Query: 40 PEAPSPPSADVNSPPPLP---PPTSPGGPKELEGQEPEPRPTEEEPGSPWSGPDELEP 94
P P PP PPP+P PP PG P +G P P P P P P L P
Sbjct: 288 PLGPLPPGP----PPPVPGYGPP--PGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAP 339
Score = 30.8 bits (68), Expect = 6.7
Identities = 18/57 (31%), Positives = 22/57 (38%), Gaps = 11/57 (19%)
Query: 40 PEAPSPPSADVNSPPPL---------PP--PTSPGGPKELEGQEPEPRPTEEEPGSP 85
P PP+ PPP+ PP P PG P + G P P P + G P
Sbjct: 261 PPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPP 317
>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
Length = 1499
Score = 78.2 bits (191), Expect = 4e-14
Identities = 156/605 (25%), Positives = 188/605 (31%), Gaps = 161/605 (26%)
Query: 377 GSKGEIYSPG-AGHPATKLPPDSLGSFQQQHTALQGPLASADLGLAPTPSPGLDRKALAE 435
G G SPG +G P PP LQG + G+A TP P DR +
Sbjct: 738 GPDGPKGSPGPSGTPGDTGPP-----------GLQG--MPGERGIAGTPGPKGDRGGI-- 782
Query: 436 ATNGEARAEPLAQNGGSS--------EPPAAPRSIKVEAVEEPEAAPILGP--------- 478
GE AE A N G+ PA P K EP ++GP
Sbjct: 783 ---GEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEK----GEPGPRGLVGPPGSRGNPGS 835
Query: 479 -GEPGPQAPSRTPSPRSP-APARVKAELSSP-TPGSSPVPGELGLAGALFLPQYVFGPDA 535
GE GP P+ P VK E P G + PG GLAG+ GP+
Sbjct: 836 RGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGS----PGPHGPNG 891
Query: 536 APPASEILAKMSELVHSRLQQGAGAGAGGAQTGLFPGAPKGATCFECEITFSNVNNYYVH 595
P L+ G G TG FPG+
Sbjct: 892 VPG---------------LKGGRGTQGPPGATG-FPGS---------------------- 913
Query: 596 KRLYCSGRRAPEDAPAARRPKAPPGPARAPPGQPAEPDAP--RSSPGPGAREEGAGGAAT 653
+GR P P PGPA P G+P + P R PG R G G A
Sbjct: 914 -----AGRVGPPG------PAGAPGPA-GPLGEPGKEGPPGLRGDPGSHGRV-GDRGPAG 960
Query: 654 PEDGAGGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHE-----------TYTVHK 702
P G G +G G G D P+ T + + T K
Sbjct: 961 PPGGPGDKGDPGED--GQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGK 1018
Query: 703 RYYCASRHDPPPRRPAAPPGPPGPAAPPAPS-PAAPVRTRRRRKLYELHAAGAPPPPP-- 759
+ D P P PPG GP P P PA T R P P
Sbjct: 1019 VGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGL 1078
Query: 760 PGHAPAPESPRPGSGSGSGPGLAPARSPGPAADGPIDLSKKPRRPLPGAPAPALADYHEC 819
PG AP +P P G S GP GP + K P P P D+ +
Sbjct: 1079 PGSQGAPGTPGPVGAPGDAGQRGDPGSRGPI--GPPGRAGKRGLPGPQGPRGDKGDHGD- 1135
Query: 820 TACRVSFHSLEAYLAHKKYS----CPAAPPP----GALGLPAAACPYCPPNGPVRGDLLE 871
H+ ++ P P P G+ G+P P PP GPV
Sbjct: 1136 -------RGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPP-GPV------ 1181
Query: 872 HFRLAHGLLLGAPLAGPGVEARTPADRGPSPAPAPAASPQPGSRGPRDGLGPEPQEPPPG 931
GP + P GP P S G GP GP + PPG
Sbjct: 1182 ---------------GPSGKEGNPGPLGPIGPPGVRGSV--GEAGPE---GPPGEPGPPG 1221
Query: 932 PPPSP 936
PP P
Sbjct: 1222 PPGPP 1226
Score = 70.5 bits (171), Expect = 8e-12
Identities = 174/695 (25%), Positives = 215/695 (30%), Gaps = 150/695 (21%)
Query: 376 PGSKGEIYSPG-AGHPATKLPPDSLGSFQQQHTALQGPLAS-ADLGLAPTPSPGLDRKAL 433
PG+KG SPG +G P + PP S G Q T QG D G+ PG +A
Sbjct: 428 PGAKGPTGSPGTSGPPGSAGPPGSPGP--QGSTGPQGIRGQPGDPGV-----PGFKGEAG 480
Query: 434 AEATNGEARAE-PLAQNG--GSSEPPAAPRSIKVEAVEEPEAAPILG--PGEPGPQAPSR 488
+ G + P+ G G P P ++ AP PG G P
Sbjct: 481 PKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKG 540
Query: 489 TPSPRSPAPAR-VKAELSSP-TPGSSPVPGELGLAG--ALFLPQYVFGPDAAPPASEILA 544
R P + K P PG +PG GL G + P+ GP AP
Sbjct: 541 AQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPG 600
Query: 545 KMSELVHSRLQQGAGAGAGGAQTGLFPGAP-----------KGATCFECEITFSNVNNYY 593
+ R Q G+ G + PG P +GA + E+
Sbjct: 601 PPGS-IGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVG-------- 651
Query: 594 VHKRLYCSGRRAPEDAPAARRPKAPPGPAR-----APPGQPAE----------------- 631
SG P R + PPGP PPG P E
Sbjct: 652 ------PSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVG 705
Query: 632 PDAPRSSPG-PGAR-EEGAGGAATPEDGAGGRGSEGSQ-SPGSSVDDAEDDP-------- 680
P PR G PG R E G G + AGG G +G + SPG S + P
Sbjct: 706 PLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPG 765
Query: 681 SRTLCEACNIRFSRH---ETYTVHKRYYCASRHDPPPRRPAAPPGPPGPAAPPAPS---- 733
R + + R E +R P P P P GP G P P
Sbjct: 766 ERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVG 825
Query: 734 -PAAPVRTRRRRKLYELHAAGAPPPPPPGHAPA----PESPRPGSGSGSGPGLAPARSPG 788
P + R + A G P P P P P +GS A SPG
Sbjct: 826 PPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPG 885
Query: 789 PAADGPIDLSKKPRRPLPGAPAPALADYHECTACRVSFHSLEAYLAHKKYSCPAAPPPGA 848
P + K R G P A +A RV PPG
Sbjct: 886 PHGPNGVPGLKGGR----GTQGPPGATGFPGSAGRVG-------------------PPGP 922
Query: 849 LGLPAAACPYCPPN--GP--VRGDLLEHFRLAHGLLLGAP-----LAGPGVEARTPADRG 899
G P A P P GP +RGD H R+ G P PG + + D
Sbjct: 923 AGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGP 982
Query: 900 PSPA-----------------------PAPAASPQPGSRGPRDGLGPEPQEPPPGPPPSP 936
P PA P PA +P G GP G + P GPP S
Sbjct: 983 PGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTP--GKVGPTGATGDKGPPGPVGPPGSN 1040
Query: 937 AAAPEAVPPPPA----PPSYSDKGVQTPSKGTPAP 967
E P PA P + +G P P
Sbjct: 1041 GPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGP 1075
Score = 65.1 bits (157), Expect = 3e-10
Identities = 139/586 (23%), Positives = 183/586 (31%), Gaps = 119/586 (20%)
Query: 422 PTPSPGLDRKALAEATNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILGPGEP 481
P PG ++ G + G EP P + P A P G
Sbjct: 85 PVTPPGECCPVCSQTPGGGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGP-AGPPGSQGPR 143
Query: 482 GPQAPSRTPSPRSPAPARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGPDA-APPAS 540
G + P P PR P G VPG+ G G P + GPD + P S
Sbjct: 144 GERGPKGRPGPRGP----------QGIDGEPGVPGQPGAPGPPGHPSHP-GPDGLSRPFS 192
Query: 541 EILAKMSELVHSRLQQGAGAGAGGAQTGLFPGAPKGATCFECEITFSNVNNYYVHKRLYC 600
+A + E + G G+ G + P P+G + +
Sbjct: 193 AQMAGLDE------KSGLGSQVGLMPGSVGPVGPRGPQGLQGQ----------------- 229
Query: 601 SGRRAPEDAPAARRPKAPPGP-----ARAPPGQPAEPDAP--RSSPG-------PGARE- 645
G P P P GP PPG+P E P +PG PGAR
Sbjct: 230 QGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGF 289
Query: 646 EGAGGAATPEDGAGGRGSEGSQ----SPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVH 701
GA G + G +G EG + +PGS + P +
Sbjct: 290 PGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPL-------GPRGMPG 342
Query: 702 KRYYCASRHDPPPRRPAAPPGPPGPAAPPA--PSPAAPVRTRRRRKLYELHAAGAPPPP- 758
+R + P R PG PGP P S P + + A G P
Sbjct: 343 ERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQG 402
Query: 759 ------PPGHAPAPESP----RPGSGSGSGPGLAPARSPGPAADGPIDLSKKPRRPLPGA 808
PPG +P P G+ GP +P S P + GP PG+
Sbjct: 403 QRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGP-----------PGS 451
Query: 809 PAPALADYHECTACRVSFHSLEAYLAHKKYSCPAAPPPGALGLPAAACPYCPP-----NG 863
P P + + + + + A P G G P PP G
Sbjct: 452 PGPQGSTGPQGIRGQPGDPGVPGFKGE-------AGPKGEPGPHGIQGPIGPPGEEGKRG 504
Query: 864 PVRGDLLEHFRLAHGLLLGAPLAGPGVEARTPADRG-PSPAPAPAASPQPGSRGPRDGLG 922
P RGD +G P GP E P +RG P P G RGP G
Sbjct: 505 P-RGD---------PGTVGPP--GPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSG 552
Query: 923 PEPQEPPPGPPPSPAAAPEAVPPPPAPPSYSDKGVQTPSKGTPAPL 968
P+ + PG P P P A + GVQ P +G PL
Sbjct: 553 PKGSQGDPGRPGEPGL-------PGARGLTGNPGVQGP-EGKLGPL 590
Score = 63.9 bits (154), Expect = 7e-10
Identities = 144/605 (23%), Positives = 185/605 (30%), Gaps = 124/605 (20%)
Query: 412 PLASADLGLAPTPSP-GLDRKALAEATNGEARAEPLAQNG---GSSEP--PAAPRSIKVE 465
P A G P P GL R A+ + ++ +Q G GS P P P+ ++ +
Sbjct: 170 PGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQ 229
Query: 466 AVEEPEAAPILGPGEPGPQAPSRTPSPRSPAPARVKAELSSPTPGSSPVPGELGLAGALF 525
P PG+PGP P + P P P + + PG + PGE+G AG+
Sbjct: 230 QGGAGPTGPPGEPGDPGPMGPIGSRGPEGP-PGKPGED---GEPGRNGNPGEVGFAGSP- 284
Query: 526 LPQYVFGPDAAPPASEILAKMSELVHSRLQQGAG-AGAGGAQTGLFPGAPKGATCFECEI 584
G P A + H L+ G GA G++ P P GA
Sbjct: 285 ------GARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGA------- 331
Query: 585 TFSNVNNYYVHKRLYCSGRRAPEDAPAAR-----------------------------RP 615
+ GR P+ AP R +
Sbjct: 332 ----MGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKG 387
Query: 616 KAPPGPARAPPGQPAE-----PDAPRSSPG-PGA-REEGAGGAATPEDGAGGRGSEGSQS 668
+A P AR P G + P P SPG PGA +G GA P G G GS
Sbjct: 388 EAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAG 447
Query: 669 -PGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRPAAPPGPPGPA 727
PGS P IR + + + +P P P GPPG
Sbjct: 448 PPGSPGPQGSTGPQ-------GIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEE 500
Query: 728 APPAPSPAAPVRTRRRRKLYELHAAGAPPPPPPGHAPAPESPR-PGSGSGSGPGLAPARS 786
P PP P G AP + PGS GP A
Sbjct: 501 GKRGPRG---------------DPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGER 545
Query: 787 PGPAADGPIDLSKKPRRP-LPGAP-APALADYHECTACRVSFHSLEAYLAHKKYSCPAA- 843
+ GP P RP PG P A L L A + P +
Sbjct: 546 GPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSI 605
Query: 844 ---PPPGALGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGPGVEARTPADRGP 900
PG++GLP P P G A P RG
Sbjct: 606 GIRGQPGSMGLPGPKGSSGDPGKP----------------------GEAGNAGVPGQRG- 642
Query: 901 SPAPAPAASPQPGSRGPRDGLGPEPQEPPPGPPPSPAAAPEAVPPPPAPPSYSDKGVQTP 960
+P P G GP G ++ PPGP + +P PP PP K
Sbjct: 643 APGKDGEVGPS-GPVGPPGLAGERGEQGPPGP-----TGFQGLPGPPGPPGEGGKPGDQG 696
Query: 961 SKGTP 965
G P
Sbjct: 697 VPGDP 701
Score = 62.4 bits (150), Expect = 2e-09
Identities = 160/638 (25%), Positives = 197/638 (30%), Gaps = 162/638 (25%)
Query: 376 PGSKGEIYSPG----AGHPATKLPPDSLGSFQQQHTALQGPLASADLGLAPTPSPGLDRK 431
PGS G +PG AG + P G Q+ T GP+ S L PG
Sbjct: 374 PGSSGFPGNPGMKGEAGPTGARGPEGPQG--QRGETGPPGPVGSPGL-------PG---- 420
Query: 432 ALAEATNGEARAEPLAQNGGSSEPPAA---PRSIKVEAVEEPEAAPILG-PGEPGPQAPS 487
A T+G A+ + G+S PP + P S + P+ I G PG+PG
Sbjct: 421 --AIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQG--IRGQPGDPGVPGFK 476
Query: 488 RTPSPRS-PAPARVKAELSSP----------TPGSSPVPGELGLAGALFLPQYVFGPDAA 536
P+ P P ++ + P PG+ PG +G GA + G D
Sbjct: 477 GEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFP-GSDGL 535
Query: 537 PPASEILAKMSELVHSRLQQGAGAGAGGAQTGLFPGAPKGATCFECEITFSNVNNYYVHK 596
P + + S + G + GL PGA +G T N V
Sbjct: 536 PGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGL-PGA-RGLT-----------GNPGVQG 582
Query: 597 RLYCSGRRAPEDAPAARRPKAPPGPA--RAPPGQPAEPDAPRSSPGPGAREEGAGGAATP 654
G+ P AP PPG R PG P SS PG E
Sbjct: 583 P---EGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPG 639
Query: 655 EDGAGGRGSEGSQS-----PGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASR 709
+ GA G+ E S PG + + E P
Sbjct: 640 QRGAPGKDGEVGPSGPVGPPGLAGERGEQGP----------------------------- 670
Query: 710 HDPPPRRPAAPPGPPGP----------AAPPAPSPAAPVRTRRRRKLYELHAAGAP-PPP 758
P P PGPPGP P P P+ R R G P
Sbjct: 671 --PGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGER--------GNPGERG 720
Query: 759 PPGHAPAPESPRPGSGSG-SGPGLAPARSPGPAADGPIDLSKKP-RRPLPGAPAPALADY 816
PG P G G GP +P S P GP L P R + G P P
Sbjct: 721 EPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGP----- 775
Query: 817 HECTACRVSFHSLEAYLAHKKYSCPAAPPPGALGLPAAACPYCPPNGPVRGDLLEHFRLA 876
+ +K + A GA GLP P PP GP
Sbjct: 776 -----------KGDRGGIGEKGAEGTAGNDGARGLPG---PLGPP-GP------------ 808
Query: 877 HGLLLGAPLAGPGVEARTPADRGPSPAPAPAASPQPGSRGPRDGLGPEPQEPPPGPPPSP 936
AGP E P RG P + PGSRG G P GP P
Sbjct: 809 ---------AGPTGEKGEPGPRG--LVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQP 857
Query: 937 AAAPEAVPPPPAPPSYSDKGVQTPS--KGTPAPL-PNG 971
E P P D G P G+P P PNG
Sbjct: 858 GVKGE----PGEPGQKGDAGSPGPQGLAGSPGPHGPNG 891
Score = 55.5 bits (132), Expect = 3e-07
Identities = 112/445 (25%), Positives = 134/445 (30%), Gaps = 57/445 (12%)
Query: 375 QPGSKGEIYSPGAGHPATKLPPDSLGSFQQQHTALQGPLASADLGL-APTPSPGLDRKAL 433
QPG KGE PG A P L H P G P + G A
Sbjct: 856 QPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAG 915
Query: 434 AEATNGEARAE----PLAQNGGSSEPP-AAPRSIKVEAVEEPEAAPILGPGEPGPQAPSR 488
G A A PL + G P + A P GPG+ G
Sbjct: 916 RVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDG 975
Query: 489 TPSPRS-PAPARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGPDAAPPASEILAKMS 547
P P P PA + G +PG+ G G LP GP P
Sbjct: 976 QPGPDGPPGPAGTTGQ-----RGIVGMPGQRGERGMPGLP----GPAGTP---------- 1016
Query: 548 ELVHSRLQQGAGAGAGGAQTGLFPGAPKGATCFECEITFSNVNNYYVHKRLYCSGRRAPE 607
+ GA G + P P G+ V G +
Sbjct: 1017 -------GKVGPTGATGDKGPPGPVGPPGSN--------GPVGEPGPEGPAGNDGTPGRD 1061
Query: 608 DAPAARRPKAPPGPARAP--PGQPAEPDAPRSSPGPGAR--EEGAGGAATPEDGAGGRGS 663
A R + PGPA P G P P P +PG + + G+ G P AG RG
Sbjct: 1062 GAVGERGDRGDPGPAGLPGSQGAPGTP-GPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGL 1120
Query: 664 EGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRPAAPPGP 723
G Q P D D R + S P P P PPGP
Sbjct: 1121 PGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGP 1180
Query: 724 PGPAAPPA-PSPAAPVRTRR-RRKLYELHAAGAP-------PPPPPGHAPAPESPRPGSG 774
GP+ P P P+ R + E G P PP PPGH A G
Sbjct: 1181 VGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPGPPGHLTAALGDIMGHY 1240
Query: 775 SGSGPGLAPARSPGPAADGPIDLSK 799
S P P + AA P D +K
Sbjct: 1241 DESMPDPLPEFTEDQAA--PDDKNK 1263
Score = 35.4 bits (80), Expect = 0.27
Identities = 69/259 (26%), Positives = 80/259 (30%), Gaps = 26/259 (10%)
Query: 717 PAAPPGPPGPAAPPAPSPAAPVRTRRRRKLYELHAAGAPPPPPPGHAPAPESPRPGSGSG 776
P PPG P P R RK + P P P P PGS
Sbjct: 85 PVTPPGECCPVCSQTPG-GGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAGP-PGSQGP 142
Query: 777 SGPGLAPARSPGPAADGPIDLSKKPRRP-LPGAPAPALADYHECT-ACRVSFHSLEAYLA 834
G P PGP GP + +P P PGAP P H F + A L
Sbjct: 143 RGER-GPKGRPGPR--GPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLD 199
Query: 835 HKK-YSCPAAPPPGALGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGPGVEAR 893
K PG++G P GP L+ G GA GP E
Sbjct: 200 EKSGLGSQVGLMPGSVG----------PVGPRGPQGLQ------GQQGGAGPTGPPGEPG 243
Query: 894 TPADRGPSPAPAPAASP-QPGSRGPRDGLGPEPQEPPPGPPPSPAAAPEAVPPPPAPPSY 952
P GP + P P +PG G G P E P P A P
Sbjct: 244 DPGPMGPIGSRGPEGPPGKPGEDG-EPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHR 302
Query: 953 SDKGVQTPSKGTPAPLPNG 971
KG++ P AP G
Sbjct: 303 GHKGLEGPKGEVGAPGSKG 321
Score = 30.4 bits (67), Expect = 8.7
Identities = 19/59 (32%), Positives = 22/59 (37%)
Query: 40 PEAPSPPSADVNSPPPLPPPTSPGGPKELEGQEPEPRPTEEEPGSPWSGPDELEPVVQD 98
P P PS +P PL P PG + PE P E P P P L + D
Sbjct: 1177 PPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPGPPGHLTAALGD 1235
>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
Length = 464
Score = 77.4 bits (189), Expect = 6e-14
Identities = 69/256 (26%), Positives = 81/256 (31%), Gaps = 28/256 (10%)
Query: 711 DPPPRRPAAPPGPPGPAAPPAP-SPAAPVRTRRRRKLYELHAAGAPPPPPPGHAPAPESP 769
+ PP P+ P GPPG PP P P R L PPPPPG P P P
Sbjct: 215 EKPPAPPSLPAGPPGVKRPPPPLMNGLPPRPPLPESL---------PPPPPGGLPLPPMP 265
Query: 770 RPGSGSGSGPGLAPARSPGPAADGPIDLSKKPRR-----------PLPGAPAPALADYHE 818
G PG P P P + P P PG PA +
Sbjct: 266 PTGPAPSGPPGPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPP 325
Query: 819 CTACRVSFHSLEAYLAHKKYSCPAAPPPGALGLPAAACPYCPPNGPVRGDLLEHFRLAHG 878
+ + P PP P A + PP+ V A
Sbjct: 326 TSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPAAPA 385
Query: 879 LLLGAPLAGPGVEARTPADRGPSPAP------APAASPQ-PGSRGPRDGLGPEPQEPPPG 931
+ AP P P G P P AP PQ PG G+ P PP
Sbjct: 386 VHPQAPGVHPPAPGMHPQAPGVHPQPPGVHPSAPGVHPQPPGVHPSNPGVHPPTPMPPML 445
Query: 932 PPPSPAAAPEAVPPPP 947
PP P+ P +PPPP
Sbjct: 446 RPPLPSEGPGNIPPPP 461
Score = 47.0 bits (110), Expect = 9e-05
Identities = 37/114 (32%), Positives = 44/114 (38%), Gaps = 19/114 (16%)
Query: 871 EHFRLAHGLLLGAPLAGPGVEARTPADRGPSPA---------PAPAASPQPGSRG----P 917
+ F L + P A P + A P + P P P P + P P G P
Sbjct: 204 KQFFLQFHFKMEKPPAPPSLPAGPPGVKRPPPPLMNGLPPRPPLPESLPPPPPGGLPLPP 263
Query: 918 RDGLGPEPQEPPPGPPPSPAAAPEAVPPPPA--PPSYSDKGVQTPSKGTPAPLP 969
GP P PPGPP P AP PP P PP+ GV P+ G P P
Sbjct: 264 MPPTGPAPSG-PPGPPQLPPPAPGVHPPAPVVHPPA---SGVHPPAPGVHPPAP 313
Score = 46.2 bits (108), Expect = 2e-04
Identities = 72/300 (24%), Positives = 91/300 (30%), Gaps = 58/300 (19%)
Query: 467 VEEPEAAPILGPGEPGPQAPSRTPSPRSPAPARVKAELSSPTPGSSPVPGELGLAGALFL 526
+E+P A P L G PG + P P + L P PG P+P A
Sbjct: 214 MEKPPAPPSLPAGPPGVKRPPPPLMNGLPPRPPLPESLPPPPPGGLPLPPMPPTGPA--- 270
Query: 527 PQYVFGPDAAPPASEILAKMSELVHSRLQQGAGAGAGGAQTGLFPGAPKGATCFECEITF 586
P GP PP + + + +VH +G G+ P AP
Sbjct: 271 PSGPPGPPQLPPPAPGVHPPAPVVHP-----PASGVHPPAPGVHPPAP------------ 313
Query: 587 SNVNNYYVHKRLYCSGRRAPEDAPAARRPKA---PPGPARAPPGQPAEPDAPRSSPGPGA 643
V+ SG P AP P PP P PP P AP P P A
Sbjct: 314 -GVHPPAPGVHPPTSGVHPP--APGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSA 370
Query: 644 REEGAGGAATPEDGAGGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKR 703
P A + G P + + VH +
Sbjct: 371 GVHPQAPGVHPAAPAVHPQAPGVHPPAPGM--------------------HPQAPGVHPQ 410
Query: 704 YYCASRHDPPPRRPAAP---PGPPG-PAAPPAPSPAAPVRTRRRRKLYELHAAGAPPPPP 759
PP P+AP P PPG + P P P+ R L PPPPP
Sbjct: 411 --------PPGVHPSAPGVHPQPPGVHPSNPGVHPPTPMPPMLRPPLPSEGPGNIPPPPP 462
Score = 43.5 bits (101), Expect = 0.001
Identities = 46/142 (32%), Positives = 49/142 (34%), Gaps = 39/142 (27%)
Query: 835 HKKYSCPAAPPPGALGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGPGVEART 894
H K P APP G P P P L+ G P P E+
Sbjct: 211 HFKMEKPPAPPSLPAGPPGVKRPPPP------------------LMNGLPPRPPLPESLP 252
Query: 895 PADRGPSPAPA-PAASPQP-GSRGPRDGLGPEPQEPPPGPPPSPAAAPEAVPP-----PP 947
P G P P P P P G GP PQ PPP P P AP PP PP
Sbjct: 253 PPPPGGLPLPPMPPTGPAPSGPPGP-------PQLPPPAPGVHP-PAPVVHPPASGVHPP 304
Query: 948 APPSYSDKGVQTPSKGTPAPLP 969
AP GV P+ G P P
Sbjct: 305 AP------GVHPPAPGVHPPAP 320
Score = 32.3 bits (72), Expect = 2.3
Identities = 17/49 (34%), Positives = 21/49 (42%), Gaps = 2/49 (4%)
Query: 32 HMEQKATAPEAPS--PPSADVNSPPPLPPPTSPGGPKELEGQEPEPRPT 78
H P+ P P + V+ P P+PP P P E G P P PT
Sbjct: 415 HPSAPGVHPQPPGVHPSNPGVHPPTPMPPMLRPPLPSEGPGNIPPPPPT 463
Score = 31.2 bits (69), Expect = 5.1
Identities = 36/138 (26%), Positives = 50/138 (36%), Gaps = 16/138 (11%)
Query: 384 SPGAGHPATKLPPDSLGSFQQQHTALQGPLASADLGLAPTPSPGLDRKALAEATNGEARA 443
+PG PA + P + G H G A G+ P PS G+ +A G A
Sbjct: 333 APGVHPPAPGVHPPAPGV----HPPAPGVHPPAP-GVHPPPSAGVHPQA-----PGVHPA 382
Query: 444 EPLAQNGGSSEPPAAPRSIKVEAVEEPE------AAPILGPGEPGPQAPSRTPSPRSPAP 497
P P AP P+ +AP + P PG + P +P P
Sbjct: 383 APAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHPSAPGVHPQPPGVHPSNPGVHPPTPMP 442
Query: 498 ARVKAELSSPTPGSSPVP 515
++ L S PG+ P P
Sbjct: 443 PMLRPPLPSEGPGNIPPP 460
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 77.0 bits (188), Expect = 8e-14
Identities = 162/656 (24%), Positives = 206/656 (31%), Gaps = 150/656 (22%)
Query: 396 PDSL-----GSFQQQHTALQGPLASADLGLAPTPSPGLDRKALAEATNGEARAEPL---- 446
PDSL SF + G A+ D G A P D KA A G +P
Sbjct: 935 PDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYC 994
Query: 447 ---AQNGGSSEP-----PAAPRSIKVEAVEEPEAAPILGPGEPGPQAPSRTPSPRSPAPA 498
A G P P P + EP GP + P P P P +PA +
Sbjct: 995 PGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPA-S 1053
Query: 499 RVKAELSSPTPGSSPVPGELGLAG---------------ALFLPQYVFGPD---AAPPAS 540
K L+SP S+ L + L+ +Y F D A PA
Sbjct: 1054 EPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPKKLYAQEYEFEADEDKADVPAD 1113
Query: 541 EIL--AKMSELVHSRLQQGAGAGAGGAQTGLFPGAPKGATCFECEITFSNVNNYYVHKRL 598
L ++ +LV S + A + G P G +R
Sbjct: 1114 IRLNPRRLPDLVSSCRSRPALSPLGDIDFCPPNPGPDGP------------------RRR 1155
Query: 599 YCSGRRAPEDAPAARRPKAPPG------PARAPPGQPAEPDAPRSSP-----GPGAREEG 647
+A D P RP+ P P A P + P P G G + E
Sbjct: 1156 GRKPTKAKRDGPP--RPRGRPRIRPLEVPTTAGPASASTPTDGAKKPRGRGRGRGRKAEE 1213
Query: 648 AGGA------------ATPEDGAGGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRH 695
AGG + P+ G G S G G+ + + +R EA I+
Sbjct: 1214 AGGTRLEPLKPLKIKLSVPKAGEGLGTSSGDAISGTDHNSLDSSLTREKIEA-KIK-EVE 1271
Query: 696 ETYTVHKRYYCAS---------RHDPPPRRPAAPPGPPGPAAPPAPSPAAPVRTRRRRKL 746
E K + AS RH P + PP P + PP+
Sbjct: 1272 EKQPEMKSGFMASFLDFLKSGKRHPPLYQAGLTPPLSPPKSVPPS--------------- 1316
Query: 747 YELHAAGAPPPPPPGHAPAPESPRPGSGSGSGPGLAPARSPGPAADGPID---LSKKPRR 803
+ A G P PP PA P P G G L A S G P L ++ +R
Sbjct: 1317 --VPARGLQPQPPA--TPAVPHPPPSGAFGLGGALEAAESEGLGLGCPSPCKRLDEELKR 1372
Query: 804 PLPGAPAPAL---------ADYHECTACRVSFHSLEAYLAHKKYSCPAAPPPGALGLPAA 854
L P+ + D E + +S K S P PP PAA
Sbjct: 1373 NLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLA----PAA 1428
Query: 855 ACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGPGVEARTPA-DRGPSPAPAPAASPQPG 913
A P PP L G P A P + P P P PA +PQP
Sbjct: 1429 AVPGPPP------------------LPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQ 1470
Query: 914 SRGPRDGLGPEPQEPPPGPPPSPAAAPEAVPPPPAPPSYSDKGVQTPSKGTPAPLP 969
P P PQ P PPP A P + PPPP PP P PA P
Sbjct: 1471 PPPP----PPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAP 1522
Score = 63.5 bits (153), Expect = 9e-10
Identities = 157/662 (23%), Positives = 197/662 (29%), Gaps = 148/662 (22%)
Query: 378 SKGEIYSPGAGHPATKLPPDSLGSFQQQHT-ALQGPLASADLGLAPTPSPGLDRKALAEA 436
SK YS G P + PP L + Q LQG L G+ P PG
Sbjct: 470 SKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQL----YGVQGEPYPG--------- 516
Query: 437 TNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILGPGEPGPQAPSRTPSPRSPA 496
P A + G P A S+ P + G G PS +
Sbjct: 517 --------PAAHSQGL---PTASPSLSYSTGHSPALS-----GHGGGWGPSSLGGGGEAS 560
Query: 497 PARVKAELSSP-TPGSSPVPGELGLAGALFLPQYVFGPDAAPPASEILAKMSELVHSRLQ 555
P+ + L SP G P G G G P APP + A
Sbjct: 561 PSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAA---------- 610
Query: 556 QGAGAGAG---GAQTGLFPGAPKGATCFECEITFSNVNNYYVHKRLYCSGRRAPEDAPA- 611
GAG G G++ PG P + E ++ R + ED A
Sbjct: 611 -GAGGYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDGAAD 669
Query: 612 ARRPKAPPGPARAPPGQPAE----------------PDAPRSSPGPGAREEGAG------ 649
A + G A PPG P E A A E G G
Sbjct: 670 ASKGLGGSGGAGGPPGTPYELAKEDPQRYHLQSVIRTSASLDEGATAALELGLGRLKEKK 729
Query: 650 -----GAATPED--------GAGGRG-----SEGSQSPGSSVDDAEDDPSRTLCEACNIR 691
G TPE GAG + + P + + P L EA
Sbjct: 730 KGPERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQPTPHGLLLEAGGPD 789
Query: 692 FSRHETYTVHKRYYCASRHDPPPRRPAAPPG------------PPGPAAPPAPSPAAPVR 739
+ H P P A+ G P P PP P P P++
Sbjct: 790 LPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQ 849
Query: 740 TRRRRKLYELHAAGAPPP--------PPPGH------APAPESPRPGSGSGSGPGLAPAR 785
+ + L A AP P PPG A P P PG +G GP + +
Sbjct: 850 LEAHLRSHGLEPA-APSPRLRPEESLDPPGAMQELLGALEPLPPAPGD-TGVGPPNSEGK 907
Query: 786 SPGPAADGPIDLSKKPRRPLPGA----PAPALADYHECTACRVSFHSLEAYL---AHKKY 838
P A P K R +P P L D R F ++E A Y
Sbjct: 908 DPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEE-----RSFFPTMEEMFGGGAADDY 962
Query: 839 SCPAAPPPGALGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGPGVEARTPADR 898
A PP G P A PP GP D + G G G++ P +
Sbjct: 963 G--KAGPPEDEGDPKAGAG--PPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPEL 1018
Query: 899 GPSPAPAPAASPQPGSRGPRDGLGPEPQEPPPGPPPSPAAAPEAVPPPPAPPSYSDKGVQ 958
+ P Q G P PPP PPP PPPPAP S G+
Sbjct: 1019 PSTVNAEPLGLIQSG---------PHQAAPPPPPPP---------PPPPAPASEPKGGLT 1060
Query: 959 TP 960
+P
Sbjct: 1061 SP 1062
Score = 61.2 bits (147), Expect = 5e-09
Identities = 158/687 (22%), Positives = 212/687 (30%), Gaps = 160/687 (23%)
Query: 372 MVCQPGSKGEIYSPGAGHPATKLPPDSLGSFQQQHTALQGPLASADLGLAPTP------- 424
++ PG K GA PP + + +L GP A+ G A
Sbjct: 383 IIQSPGYKTGKGGYGAAAGGATRPPPPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQA 442
Query: 425 -SPGLDRKALAEATNGEA----RAEPLAQ----NGGSSEPPAAPRSIKVEAVEEPEAAPI 475
SPG + L G+ +A+ L++ +GG +PP+ P + + +
Sbjct: 443 YSPGQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQL 502
Query: 476 LGP-----GEPGPQAPSRTPSPRSPAPARVKAELSSPT---PGSSPVPGELGLAGALFLP 527
G GEP P + + + +P+ + SP G P LG G P
Sbjct: 503 QGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTGHSPALSGHGGGWGPSSLG-GGGEASP 561
Query: 528 QYVFGPDAAPPASEILAKMSELVHSRLQQGAGAGAGGAQTGLFPGAPKGATCFECEITFS 587
++ P +PPA+ G G G PGAP + + S
Sbjct: 562 SHIIRPLQSPPAT----------------GRPPGVGS------PGAPGK---YLSSVLAS 596
Query: 588 NVNNYYVHKRLYCSGRRAPEDAPAARRPKAPPGPARAPPGQPAE------------PDAP 635
Y +G + A PG PP + E P P
Sbjct: 597 APFLAPPGAGSYAAGAGGYKGKGDGSELLAGPG---GPPAERTEDEEFLIQHLLQAPSPP 653
Query: 636 RSSPGPGAREEGAGGAATPEDGAGGRGSEGSQSPGSSVDDAEDDPSRT-LCEACNIRFSR 694
R+S G G GAA G GG G G PG+ + A++DP R L S
Sbjct: 654 RTSGADGL--VGEDGAADASKGLGGSGGAGGP-PGTPYELAKEDPQRYHLQSVIRTSASL 710
Query: 695 HETYTVHKRYYCASRHDPPPRRPAAPPGPPGPAAPPAPSPAAPVRTRRRRKLYELHAAGA 754
E T A+ R GP P + V K +
Sbjct: 711 DEGAT-------AALELGLGRLKEKKKGPERGGETPEGLATSVVHYGAGAKELGAFLQKS 763
Query: 755 PPPPPPGHAPAPESPRPGSGSGSGPGLAPARSPGPAADGPIDLSKKPRRPLPGAPAPALA 814
PPPPPP +P GP L P P P LS P +P+P+
Sbjct: 764 PPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAP------SPSPS-- 815
Query: 815 DYHECTACRVSFHSLEAYLAHKKYSCPAAPPPGALGLPAAACPYCPPNGPVRGDLLEHFR 874
A +V H LE + P PPP PP P+ L H R
Sbjct: 816 ------ASKVGVHLLEPAT---RDGAPQPPPPPP-----------PPPPPMPLQLEAHLR 855
Query: 875 LAHGLLLGAP---------LAGPGVEAR----------TPADRGPSPA------PAPA-A 908
+HGL AP L PG P D G P PA A
Sbjct: 856 -SHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYR 914
Query: 909 SPQP-GSRGPRD----------------------------GLGPEPQEPPPGPPPSPAAA 939
SP P G++ PR G G GPP
Sbjct: 915 SPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDP 974
Query: 940 PEAVPPPPAPPSYSDKGVQTPSKGTPA 966
PPP PP+Y G P + + A
Sbjct: 975 KAGAGPPPGPPAYDPYGPYCPGRASGA 1001
Score = 50.4 bits (119), Expect = 8e-06
Identities = 82/347 (23%), Positives = 107/347 (30%), Gaps = 116/347 (33%)
Query: 595 HKRLYCSGRRAPEDAPAARRPKAPP-GPARAPPGQPAEPDAPRSSPGPGAREEGAGGAAT 653
H LY +G P P + P P G PP PA P P S GA G A
Sbjct: 1295 HPPLYQAGLTPPLSPPKSVPPSVPARGLQPQPPATPAVPHPPPS----GAFGLGGALEAA 1350
Query: 654 PEDGAGGRGSEGSQSPGSSVDDA-----EDDPSRTLCEACNIRFSRHETYTVHKRYYCAS 708
+G G G SP +D+ E PS + E ++ +R ++ ++
Sbjct: 1351 ESEGLG----LGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAI--SA 1404
Query: 709 RHDPP---PRRPAAPPGPP-GPAAP---PAPSPAAPVRTRRRRKLYELHAAGAPPPPPPG 761
DPP P+ + P GPP PAA P P P P ++ G P PP
Sbjct: 1405 LDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLP----------SANSNGTPEPPLLE 1454
Query: 762 HAPAPESPRPGSGSGSGPGLAPARSPGPAADGPIDLSKKPRRPLPGAPAPALADYHECTA 821
P P P PA +P P +P P P P
Sbjct: 1455 EKPPPTPP-------------PAPTPQP-------------QPPPPPPPPQ--------- 1479
Query: 822 CRVSFHSLEAYLAHKKYSCPAAPPPGALGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLL 881
PA P P L P + P PP P
Sbjct: 1480 -------------------PALPSPPPLVAPTPSSPPPPPLPP----------------- 1503
Query: 882 GAPLAGPGVEARTPADRGPSPAPAPAASPQPGSRGPRDGLGPEPQEP 928
P PSP P P + P + P + P P++P
Sbjct: 1504 ------------PPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDP 1538
Score = 50.1 bits (118), Expect = 1e-05
Identities = 139/594 (23%), Positives = 178/594 (29%), Gaps = 171/594 (28%)
Query: 410 QGPLASADLGLAPTPSPGLDRKALAEATNGEARAEPLAQNGGSSEPPAAPRSIKVE---- 465
Q P + LG G+ L A G A+ P G +PP PR + +
Sbjct: 195 QAPTVPSSLGFERLAGGGV----LGPAGLGPAQTPPYRP--GPPDPPPPPRHLPTQFNLL 248
Query: 466 ------AVEEPEAAPIL------GPGEPGP--------------QAPSRTPSPRSPAPAR 499
A +++P L PG P P Q P+ P P PA
Sbjct: 249 ASSSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAH 308
Query: 500 V----------------KAELS-SPTPGSSPVPGELGLAGALFLPQYVFGPDAAPPASEI 542
+A L+ SP G P PG AG P A P+
Sbjct: 309 ALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPG----AGE---------PSKAGPSGAT 355
Query: 543 LAKMSELVHSRLQQGAGAGAGGAQTGLFPGAPKGATCFECEITFSNVNNYYVHKRLYCSG 602
G GAG GG G
Sbjct: 356 AGASGRATGPEAAGGGGAGGGGG------------------------------------G 379
Query: 603 RRAPEDAPAARRPKAPPGPARAPPGQPAEPDAPRSSPGPGAREEGAGGAATPEDGAGGRG 662
R +P + K G A G P PRS+ P + G AA A G G
Sbjct: 380 YRPIIQSPGYKTGKGGYGAAA---GGATRPPPPRSTATPKCQSLGGPAAAYATGKASGAG 436
Query: 663 SEGSQ--SPGSSVDDAEDDPSRTL-CEACNIRFSRHETYTVHKRYYCASRHDPPPRRPAA 719
G Q SPG P L +A F + + K S PP+ P+
Sbjct: 437 GAGGQAYSPG--------QPQGLLGPQAYGQGFGGGQAQDLSK---APSYSGGPPQPPSG 485
Query: 720 PPGPPGPAAPPAPSPAAPVRTRRRRKLYELHAAGAPPPPPPGHAPAPESPRPGSG----- 774
PP PPG A + SP + + +LY + G P P P H+ + P
Sbjct: 486 PP-PPGLATCQSYSP-----DQLQGQLYGVQ--GEPYPGPAAHSQGLPTASPSLSYSTGH 537
Query: 775 ----SGSGPGLAPARSPGPAADGPIDLSKKPRRPLPGAPAPALADYHECTACRVSFHSLE 830
SG G G P+ G P + + + P P + S +
Sbjct: 538 SPALSGHGGGWGPSSLGGGGEASPSHIIRPLQSPPATGRPPGVG----------SPGAPG 587
Query: 831 AYLAHKKYSCPAAPPPGALGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGPGV 890
YL+ S P PPGA A A Y +GD E LL P GP
Sbjct: 588 KYLSSVLASAPFLAPPGAGSYAAGAGGY-----KGKGDGSE--------LLAGP-GGPPA 633
Query: 891 EARTPAD-------RGPSPAPAPAASPQPGSRGPRD---GLGPE-PQEPPPGPP 933
E + + PSP A G G D GLG PPG P
Sbjct: 634 ERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDGAADASKGLGGSGGAGGPPGTP 687
Score = 46.2 bits (108), Expect = 2e-04
Identities = 137/600 (22%), Positives = 175/600 (29%), Gaps = 173/600 (28%)
Query: 476 LGPGEPGPQA--PSRTPSPRSPAPARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGP 533
LG GEP P A PS+ + A A +A G G G + P Y G
Sbjct: 334 LGGGEPSPGAGEPSKAGPSGATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGK 393
Query: 534 DA-----------APPASEILAKMSEL--VHSRLQQGAGAGAGGAQTGLF-PGAPKGATC 579
PP S K L + G +GAGGA + PG P+G
Sbjct: 394 GGYGAAAGGATRPPPPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQGL-- 451
Query: 580 FECEITFSNVNNYYVHKRLYCSGRRAPEDAPAARRPKAPPGPARAPPGQPA--------- 630
+ + Y G + ++ P GP + P G P
Sbjct: 452 --------------LGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSY 497
Query: 631 EPDAPRSS---------PGPGAREEGAGGAATPEDGAGGR-----GSEGSQSPGSSVDDA 676
PD + PGP A +G A+ + G G G P S
Sbjct: 498 SPDQLQGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTGHSPALSGHGGGWGPSSLGGGG 557
Query: 677 EDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRPAAPPGPPGPAAPPAPSPAA 736
E PS + P + P A PPG +P AP
Sbjct: 558 EASPSHII---------------------------RPLQSPPATGRPPGVGSPGAPG--- 587
Query: 737 PVRTRRRRKLYELHAAGAP--PPPPPGHAPAPESPRPGSGSGS----GPGLAPA------ 784
K A AP PP G A G G GS GPG PA
Sbjct: 588 --------KYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGDGSELLAGPGGPPAERTEDE 639
Query: 785 --------RSPGP----------AADGPIDLSKK-----PRRPLPGAPAPALAD----YH 817
++P P DG D SK PG P + YH
Sbjct: 640 EFLIQHLLQAPSPPRTSGADGLVGEDGAADASKGLGGSGGAGGPPGTPYELAKEDPQRYH 699
Query: 818 ECTACRVSFHSLEAYLA---------HKKYSCPAAPPPGALGLPAAACPY---------- 858
+ R S E A +K P GL + Y
Sbjct: 700 LQSVIRTSASLDEGATAALELGLGRLKEKKKGPERGGETPEGLATSVVHYGAGAKELGAF 759
Query: 859 ---CPPNGPVRGDLLEHFRLAHGLLLGAPLAGPGVEARTPADRGPSPAPAPAA---SPQP 912
PP P + HGLLL A GP + P P P P+ +P P
Sbjct: 760 LQKSPPPPPPTAQSTQP--TPHGLLLEA--GGPDLPLVLPP---PPPQLLPSVLSHAPSP 812
Query: 913 GSRGPRDG---LGPEPQEPPPGPPPSPAAAPEAVPPPPAPPSYSDKGVQTPSKGTPAPLP 969
+ G L P ++ P PPP P PPPP P + +++ AP P
Sbjct: 813 SPSASKVGVHLLEPATRDGAPQPPPPPP------PPPPPMPLQLEAHLRSHGLEPAAPSP 866
Score = 43.5 bits (101), Expect = 0.001
Identities = 59/231 (25%), Positives = 73/231 (31%), Gaps = 37/231 (16%)
Query: 713 PPRRPAAPPGPPGPAAPPAPSPAAPVRTRRRRKLYELHAAGAPPPPPPGHAPAPESPRPG 772
P + P PGPP P PP P + L AA A A SP+
Sbjct: 221 PAQTPPYRPGPPDPPPPPRHLPT------QFNLLASSSAAAA--------AAEQSSPQLY 266
Query: 773 SGSGSGPGLAPARSPGPAADGPIDLSKKPRRPLPGAPAPALADYHECTACRVSFHSL--E 830
+ SG+ PG P P D I ++P P P P +C S+ S+
Sbjct: 267 NFSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHR 326
Query: 831 AYLAHKKYSCPAAPPPGALGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGPGV 890
A LA P PGA G P+ A P G GA G
Sbjct: 327 ANLACSPLG-GGEPSPGA-GEPSKAGP-------------------SGATAGASGRATGP 365
Query: 891 EARTPADRGPSPAPAPAASPQPGSRGPRDGLGPEPQEPPPGPPPSPAAAPE 941
EA G PG + + G G PPP A P+
Sbjct: 366 EAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAAGGATRPPPPRSTATPK 416
Score = 43.5 bits (101), Expect = 0.001
Identities = 130/555 (23%), Positives = 169/555 (30%), Gaps = 177/555 (31%)
Query: 455 PPAAPRSIKVEAVEEPEAAP--------ILGPG--EPGPQAPSRTPSPRSPAPARVKAEL 504
PP P+ + P +P +L P + PQ P P P P P +++A L
Sbjct: 795 PPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHL 854
Query: 505 SS-------PTPGSSPV-----PGELG-LAGALF-LPQYVFGPDAAPPASEILAKMSELV 550
S P+P P PG + L GAL LP PP SE
Sbjct: 855 RSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSE--------- 905
Query: 551 HSRLQQGAGAGAGGAQTGLFPGAPKGATCFECEITFSNVNNYYVHKRLYCSGRRAPEDAP 610
+ GA T P + CF + +++ G A +
Sbjct: 906 -GKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGK 964
Query: 611 AARR-----PKAPPGPARAPPGQPAEPDAPRSSPGPGAREEGAGGAATPEDGAGGRGSEG 665
A PKA GP PPG PA PG R GAG PE G G +
Sbjct: 965 AGPPEDEGDPKAGAGP---PPGPPAYDPYGPYCPG---RASGAG----PE--TPGLGLDP 1012
Query: 666 SQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRPAAPPGPPG 725
++ P + PS E + S H P P PP PP
Sbjct: 1013 NKPP--------ELPSTVNAEPLGLIQS--------------GPHQAAPPPPPPPPPPPA 1050
Query: 726 PAAPPAPSPAAPV--RTRRRRKL----YELHAAGAPPPPPPGHAPAPESPRPGSGSGSGP 779
PA+ P +P+ T+ ++ L + L PP P A E
Sbjct: 1051 PASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPKKLYAQE------------ 1098
Query: 780 GLAPARSPGPAADGPIDLSKKPRRPLPGAPAPALADYHECTACRVSFHSLEAYLAHKKYS 839
+ AD P D+ PRR LP ++CR S
Sbjct: 1099 --YEFEADEDKADVPADIRLNPRR-LPDL----------VSSCR---------------S 1130
Query: 840 CPAAPPPGALGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGPGVEARTPADRG 899
PA P G + +CPPN PG + P RG
Sbjct: 1131 RPALSPLGDI-------DFCPPN-------------------------PGPDG--PRRRG 1156
Query: 900 PSPAPAPAASPQPGSRGPRDGLGPEPQEPPPGPPPSPAAAPEAVPPPPAPPSYSDKGVQT 959
P ++ RDG PP P P P VP P S S T
Sbjct: 1157 RKP-----------TKAKRDG--------PPRPRGRPRIRPLEVPTTAGPASAS-----T 1192
Query: 960 PSKGTPAPLPNGNHR 974
P+ G P G R
Sbjct: 1193 PTDGAKKPRGRGRGR 1207
Score = 42.0 bits (97), Expect = 0.003
Identities = 47/159 (29%), Positives = 52/159 (32%), Gaps = 34/159 (21%)
Query: 841 PAAPPPGALGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGPGVEARTPADRGP 900
P +PP L P P P L RLA G +LG GP A+TP R
Sbjct: 174 PFSPPANGLLSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPAGLGP---AQTPPYRPG 230
Query: 901 SPAPAPAASPQPG-----SRGPRDGLGPEPQEP--------PPGPPPSPAAAP------- 940
P P P P + E P PGPPP A P
Sbjct: 231 PPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIK 290
Query: 941 ------EAVPPPPAPPS-----YSDKGVQTPSKGTPAPL 968
A PPPP PP+ Y G PS G A L
Sbjct: 291 HYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANL 329
Score = 38.1 bits (87), Expect = 0.042
Identities = 58/236 (24%), Positives = 79/236 (33%), Gaps = 39/236 (16%)
Query: 606 PEDAPAARRPKAPPGPARAPPGQPAEPDAPRSSPGP----------GAREEGAGGAATPE 655
P PA P PP PA AP P E A S P ++E A +
Sbjct: 1503 PPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKKQETAAVCGETD 1562
Query: 656 DGAGGRGSEG-SQSPGSSVDDAEDDPSRTLC--------EACNIRFSRHETYTVH----K 702
+ AG G EG + V AED PS L ++ + + +T +
Sbjct: 1563 EEAGESGGEGIFRERDEFVIRAEDIPSLKLALQTGREPPPIWRVQKALLQKFTPEIKDGQ 1622
Query: 703 RYYCASRHDPPPRRPAAPPGPPGPAAPPAPSPAAPVRTRRRRKLYELHAAGAP---PPPP 759
R +CA+ + G G A +K Y A P PP P
Sbjct: 1623 RQFCATSN---------YLGYFGDAKNRYQRLYVKFLENVNKKDYVRVCARKPWHRPPVP 1673
Query: 760 PGHAPAPESPRPGSGSGSGPGLAPARSPGPAADGPIDLSKKPRR----PLPGAPAP 811
+ ++P GS + P APA P P K P + +P PAP
Sbjct: 1674 VRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAP 1729
Score = 35.8 bits (81), Expect = 0.21
Identities = 23/69 (33%), Positives = 26/69 (37%), Gaps = 16/69 (23%)
Query: 40 PEAPSPPSADVNSPPPL---------PPPTSPGGPKELEGQEPEPRPT-------EEEPG 83
P P PP + SPPPL PPP P P + P P P EEP
Sbjct: 1472 PPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPA 1531
Query: 84 SPWSGPDEL 92
+P EL
Sbjct: 1532 APSPEDPEL 1540
Score = 34.7 bits (78), Expect = 0.46
Identities = 23/69 (33%), Positives = 31/69 (44%), Gaps = 6/69 (8%)
Query: 619 PGPARAPPGQPAEPDAPRSSPGPGAREEG---AGGAATPEDGAGGRGSEGSQSPGSSVDD 675
P +R P +P + A P P R++ AGG AT G G S+ SPG+ +D
Sbjct: 1776 PATSRLPKARPTKVKA---EPPPKKRKKWLKEAGGNATAGGGPPGSSSDSESSPGAPSED 1832
Query: 676 AEDDPSRTL 684
P R L
Sbjct: 1833 ERAVPGRLL 1841
Score = 33.9 bits (76), Expect = 0.79
Identities = 23/67 (34%), Positives = 26/67 (38%), Gaps = 9/67 (13%)
Query: 892 ARTPADRGPSPAPAPAASPQPGSRGPRDGLGPEPQEPPPGP--------PPSPAAAPE-A 942
AR P R P P + P S G P+ PPP P P PE A
Sbjct: 1663 ARKPWHRPPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETA 1722
Query: 943 VPPPPAP 949
+P PPAP
Sbjct: 1723 MPEPPAP 1729
Score = 32.7 bits (73), Expect = 1.8
Identities = 24/67 (35%), Positives = 27/67 (40%), Gaps = 11/67 (16%)
Query: 32 HMEQKATAPEAPSPPSADVNSPPPLPPPTSPGGPKE------LEGQEPEPRPTEEEPGSP 85
H+ + AT AP PP PPP PPP P + LE P PR EE P
Sbjct: 822 HLLEPATRDGAPQPP-----PPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDP 876
Query: 86 WSGPDEL 92
EL
Sbjct: 877 PGAMQEL 883
Score = 32.3 bits (72), Expect = 2.3
Identities = 45/186 (24%), Positives = 63/186 (33%), Gaps = 18/186 (9%)
Query: 45 PPSADVNSPPPLPPPTSPGGPKELEGQEPEPRPTEEEPGSPWSGPDELEPVVQDGQRRIR 104
PP PPL PP S G +P+P T P P SG L ++ +
Sbjct: 1296 PPLYQAGLTPPLSPPKSVPPSVPARGLQPQPPATPAVPHPPPSGAFGLGGALEAAE---- 1351
Query: 105 ARLSLATGLSWGPFHGSVQTRASSPRQAEPSPALTLLLVDEACWLRTLPQALTEA----- 159
+ GL G + R E P+ + D R L ++++ A
Sbjct: 1352 -----SEGLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALD 1406
Query: 160 ---EANTEIHRKDDALWCRVTKPVPAGGLLSVLLTAEPHSTPGHPVKKEPAEPTCPAPAH 216
A + D VP L L +A + TP P+ +E PT P PA
Sbjct: 1407 DPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPT-PPPAP 1465
Query: 217 DLQLLP 222
Q P
Sbjct: 1466 TPQPQP 1471
Score = 32.0 bits (71), Expect = 3.0
Identities = 15/49 (30%), Positives = 17/49 (34%)
Query: 37 ATAPEAPSPPSADVNSPPPLPPPTSPGGPKELEGQEPEPRPTEEEPGSP 85
A P +P PP PP +P P P P P P P P
Sbjct: 1490 APTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDP 1538
Score = 31.6 bits (70), Expect = 3.9
Identities = 26/91 (28%), Positives = 38/91 (41%), Gaps = 6/91 (6%)
Query: 10 RQIKRSLGD-MEAREEVQLVGASHMEQKATAPEAPSPPSADVNSPPPLP--PPTSPGGPK 66
R ++ S+ + A ++ L G + +T P P+A V PPPLP P + G
Sbjct: 1392 RDLQESISSAISALDDPPLAGP---KDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTP 1448
Query: 67 ELEGQEPEPRPTEEEPGSPWSGPDELEPVVQ 97
E E +P PT +P P P Q
Sbjct: 1449 EPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQ 1479
Score = 31.2 bits (69), Expect = 5.1
Identities = 20/52 (38%), Positives = 22/52 (42%), Gaps = 6/52 (11%)
Query: 40 PEAPSPPSADVNSPP--PL----PPPTSPGGPKELEGQEPEPRPTEEEPGSP 85
P P PSA+ N P PL PPPT P P P P P + SP
Sbjct: 1434 PPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSP 1485
Score = 30.4 bits (67), Expect = 8.7
Identities = 47/190 (24%), Positives = 70/190 (36%), Gaps = 31/190 (16%)
Query: 20 EAREEVQLVGASHMEQKATAPEAPSPPSADVNSPPPLPPPTSPGGPKELEGQEPEPRPTE 79
+A+ V G+S A P+AP+PP P P +P + E P
Sbjct: 1679 QAKNPVSAGGSS-----APPPKAPAPP----------PKPETPEKTTSEKPPEQTPETAM 1723
Query: 80 EEPGSPWSGPDELEPVVQDGQRRIRARLSLATGLSWGPFHGSVQTRASSPRQAEPSPALT 139
EP +P P L PV ++ ++ R P G RA+S RQ P +L
Sbjct: 1724 PEPPAP-EKPSLLRPVEKEKEKEKVTR-------GERPLRGE---RATSGRQTRPERSLA 1772
Query: 140 LLLVDEACWLRTLPQALTEAEANTEIHRKDDALWCRVTKPVPAGGLLSVLLTAEPHSTPG 199
+ R LP+A + E K W + G +++ S+PG
Sbjct: 1773 ---TGQPATSR-LPKA-RPTKVKAEPPPKKRKKWLKEAGGNATAGGGPPGSSSDSESSPG 1827
Query: 200 HPVKKEPAEP 209
P + E A P
Sbjct: 1828 APSEDERAVP 1837
>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
sapiens]
Length = 1636
Score = 75.9 bits (185), Expect = 2e-13
Identities = 109/386 (28%), Positives = 128/386 (33%), Gaps = 74/386 (19%)
Query: 609 APAARRPKAPPGPAR--APPGQPAEPDAPRSSPGPGAREEGAGGAATPEDGAGGRGSEGS 666
AP PGPA AP P PRSSP G G AG +
Sbjct: 807 APGPHAMPVAPGPALYPAPAYTPELGLVPRSSPQHGVVSSPYVGVGPAPPVAGLPSAPPP 866
Query: 667 QSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRPAAPPGPPGP 726
Q G + A P+ T ++ H A R +P P APP P P
Sbjct: 867 QFSGPELAMAVR-PATTTVDSIQAPIPSHT----------APRPNPTP----APPPPCFP 911
Query: 727 AAPPAPSPAAPVRTRRRRKLYELHAAGAPPPPPPGHAPAPESPRPGSGSGSGPGLAPARS 786
PP P P + AGA P P H + P GP P
Sbjct: 912 VPPPQPLPTPYT-----------YPAGAKQPIPAQHHFSSGIPAGFPAPRIGPQPQPHPQ 960
Query: 787 PGPA-ADGPIDLSKKPRRPLPGAPAPALADYHECTACRVSFHSLEAYLAHKKYSCPAAPP 845
P P+ A GP + P++PLP L H F L + P AP
Sbjct: 961 PHPSQAFGP----QPPQQPLP------LQHPH-------LFPPQAPGLLPPQSPYPYAPQ 1003
Query: 846 PGALGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGPGVEARTPADRGPSPAP- 904
PG LG P GP + L AH L P GP P GP+P+
Sbjct: 1004 PGVLGQPPPPLHTQLYPGPAQDPLP-----AHSGALPFPSPGPPQPPHPPLAYGPAPSTR 1058
Query: 905 --APAASPQ----PGSRG---PRDGLGPEPQEPPPGPPPSPAAAPEAVPPP--------- 946
P A+P P S G P L P P P PGP P P P A PPP
Sbjct: 1059 PMGPQAAPLTIRGPSSAGQSTPSPHLVPSPA-PSPGPGPVPPRPPAAEPPPCLRRGAAAA 1117
Query: 947 ---PAPPSYSDKGVQTPSKGTPAPLP 969
+ P G Q+P G P P
Sbjct: 1118 DLLSSSPESQHGGTQSPGGGQPLLQP 1143
Score = 52.4 bits (124), Expect = 2e-06
Identities = 65/255 (25%), Positives = 82/255 (32%), Gaps = 44/255 (17%)
Query: 730 PAPSPAAPVRTRRRRKLYELHAAGAPPPP----PPGHAPAPESPRPGSGSGSGPGLAPAR 785
P P P AP RR+ E AG PP PP P P GS + P+
Sbjct: 716 PPPRPTAPKPLLPRREESEAVEAGDPPEELRSLPPDMVAGPRLPDTFLGSATPLHFPPSP 775
Query: 786 SPGPAADGPIDLSKKPRRPLPGAPAPALADYHECTACRVSFHSLEAYLAHKKYSCPAAPP 845
P GP LS PLP Y + P AP
Sbjct: 776 FPSSTGPGPHYLSG----PLPPG----------------------TYSGPTQLIQPRAPG 809
Query: 846 PGALGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGPGVEARTPADRGPSPAPA 905
P A+ + Y P L+ HG++ +P G G P G AP
Sbjct: 810 PHAMPVAPGPALYPAPAYTPELGLVPRSSPQHGVV-SSPYVGVGP---APPVAGLPSAPP 865
Query: 906 P-------AASPQPGSRGPRDGLGPEPQEPPPGPPPSPAAAPEAVPPPPAPPSYSDKGVQ 958
P A + +P + P P P P P+PA P P PP P +
Sbjct: 866 PQFSGPELAMAVRPATTTVDSIQAPIPSHTAPRPNPTPAPPPPCFPVPPPQPLPTP---Y 922
Query: 959 TPSKGTPAPLPNGNH 973
T G P+P +H
Sbjct: 923 TYPAGAKQPIPAQHH 937
Score = 35.4 bits (80), Expect = 0.27
Identities = 69/278 (24%), Positives = 95/278 (34%), Gaps = 57/278 (20%)
Query: 412 PLASADLGLAPTPSPGLDRKALAEATNGEARAEPLAQNGGSSEPP-----------AAPR 460
P + +LGL P SP ++ G A P+A G S PP P
Sbjct: 825 PAYTPELGLVPRSSP--QHGVVSSPYVGVGPAPPVA--GLPSAPPPQFSGPELAMAVRPA 880
Query: 461 SIKVEAVEEPEAA-----PILGPGEPGPQAPSRTPSP-----------RSPAPARVKAEL 504
+ V++++ P + P P P P P P P + P PA+
Sbjct: 881 TTTVDSIQAPIPSHTAPRPNPTPAPPPPCFPVPPPQPLPTPYTYPAGAKQPIPAQ--HHF 938
Query: 505 SSPTPGSSPVP--GELGLAGALFLPQYVFGPDAAPPASEILAKMSELVHSRLQQGAGAGA 562
SS P P P G P FGP PP + L H L G
Sbjct: 939 SSGIPAGFPAPRIGPQPQPHPQPHPSQAFGPQ--PPQQPL-----PLQHPHLFPPQAPGL 991
Query: 563 GGAQTGLFPGAPKGATCFECEITFSNVNNYYVHKRLYCSGRRAPEDAPAARRPKAPPGPA 622
Q+ +P AP+ + +H +LY + P A + P PGP
Sbjct: 992 LPPQSP-YPYAPQPGVLGQPPPP--------LHTQLYPGPAQDPLPAHSGALPFPSPGPP 1042
Query: 623 RAPPGQPAEPDAPRSSP-GPGA-----REEGAGGAATP 654
+ P A AP + P GP A R + G +TP
Sbjct: 1043 QPPHPPLAYGPAPSTRPMGPQAAPLTIRGPSSAGQSTP 1080
Score = 35.0 bits (79), Expect = 0.35
Identities = 36/118 (30%), Positives = 44/118 (37%), Gaps = 17/118 (14%)
Query: 410 QGPLASADLGLAPTPSPGLDRKALAEATNGEA--------RAEPLAQNGGSSEPPAAPRS 461
Q PL A G P PSPG + G A +A PL G SS + P
Sbjct: 1024 QDPLP-AHSGALPFPSPGPPQPPHPPLAYGPAPSTRPMGPQAAPLTIRGPSSAGQSTPSP 1082
Query: 462 IKVEAVEEPEAAPILGPGEPGPQAPSRTPSP---RSPAPARVKAELSSPTPGSSPVPG 516
V P AP GPG P+ P+ P P R A A + + G + PG
Sbjct: 1083 HLV-----PSPAPSPGPGPVPPRPPAAEPPPCLRRGAAAADLLSSSPESQHGGTQSPG 1135
Score = 34.7 bits (78), Expect = 0.46
Identities = 29/96 (30%), Positives = 37/96 (38%), Gaps = 9/96 (9%)
Query: 883 APLAGPGVEARTPADRGPSPAPAPAASPQPGSRGPRDGLGPEPQEPPP-------GPPPS 935
A L GP P P P P++SP P S + P+P+E PP GPP S
Sbjct: 1518 ASLPGPAEPPGLPPASLPESTPIPSSSPPPLSSPLPE--APQPKEEPPVPEAPSSGPPSS 1575
Query: 936 PAAAPEAVPPPPAPPSYSDKGVQTPSKGTPAPLPNG 971
++ P S +G Q SK NG
Sbjct: 1576 SLELLASLTPEAFSLDSSLRGKQRMSKHNFLQAHNG 1611
Score = 31.6 bits (70), Expect = 3.9
Identities = 17/46 (36%), Positives = 21/46 (45%), Gaps = 1/46 (2%)
Query: 23 EEVQLVGASHMEQKATAPEAPSPPSADVNSPPPLPPP-TSPGGPKE 67
+ +Q SH + AP PP V P PLP P T P G K+
Sbjct: 885 DSIQAPIPSHTAPRPNPTPAPPPPCFPVPPPQPLPTPYTYPAGAKQ 930
Score = 31.6 bits (70), Expect = 3.9
Identities = 39/136 (28%), Positives = 55/136 (40%), Gaps = 24/136 (17%)
Query: 422 PTPSPGLDRKALAEATNGEARAEPLAQNG----GSSEPPAAPRSIKVEAVEEPEAAPILG 477
P P L ++++ + ++ L G S + A SI+ E A + G
Sbjct: 1463 PPPCKPLASASISQKNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPPGGLESPVASLPG 1522
Query: 478 PGEPG--PQA--PSRTPSPRSPAPARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGP 533
P EP P A P TP P S P LSSP P +P P E P P
Sbjct: 1523 PAEPPGLPPASLPESTPIPSSSPP-----PLSSPLP-EAPQPKE--------EPPVPEAP 1568
Query: 534 DAAPPAS--EILAKMS 547
+ PP+S E+LA ++
Sbjct: 1569 SSGPPSSSLELLASLT 1584
Score = 31.2 bits (69), Expect = 5.1
Identities = 25/81 (30%), Positives = 32/81 (39%), Gaps = 20/81 (24%)
Query: 712 PPPRRPAAPPGPPGPAAPPAPSPAAPVRTRRRRKLYELHAAGAPPP---PPPGHAPAPES 768
PP + PGPA PP PA+ + P P PPP +P PE+
Sbjct: 1509 PPGGLESPVASLPGPAEPPGLPPASLPES-------------TPIPSSSPPPLSSPLPEA 1555
Query: 769 PRPGSGSGSGPGLAPARSPGP 789
P+P P + A S GP
Sbjct: 1556 PQP----KEEPPVPEAPSSGP 1572
Score = 30.4 bits (67), Expect = 8.7
Identities = 38/134 (28%), Positives = 47/134 (35%), Gaps = 15/134 (11%)
Query: 40 PEAPSPPSADVNSPP--PLPPPTSP---GGPKELEGQEPEPRPTEEEPGSPWSGPDELEP 94
P+ P PP A +P P+ P +P GP P P SP GP P
Sbjct: 1042 PQPPHPPLAYGPAPSTRPMGPQAAPLTIRGPSSAGQSTPSPHLVPSPAPSPGPGPVPPRP 1101
Query: 95 VVQDGQRRIRARLSLATGLSWGP--FHGSVQTRASSPRQAEPSPALTLLLVDEACWLRTL 152
+ +R + A LS P HG Q+ P L VD A R
Sbjct: 1102 PAAEPPPCLRRGAAAADLLSSSPESQHGGTQSPGGG------QPLLQPTKVDAAEGRR-- 1153
Query: 153 PQALTEAEANTEIH 166
PQAL E + H
Sbjct: 1154 PQALRLIERDPYEH 1167
Score = 30.4 bits (67), Expect = 8.7
Identities = 21/65 (32%), Positives = 27/65 (41%), Gaps = 2/65 (3%)
Query: 904 PAPAASPQPGSRGPRDGLGPEPQEPPPGPP-PSPAAAPEAVPPPPAPPSYSDKGV-QTPS 961
P SP GP + G P P P PS + P + P P AP + V + PS
Sbjct: 1510 PGGLESPVASLPGPAEPPGLPPASLPESTPIPSSSPPPLSSPLPEAPQPKEEPPVPEAPS 1569
Query: 962 KGTPA 966
G P+
Sbjct: 1570 SGPPS 1574
Score = 30.4 bits (67), Expect = 8.7
Identities = 22/64 (34%), Positives = 26/64 (40%), Gaps = 13/64 (20%)
Query: 717 PAAPPG-PPG--PAAPPAPSPAAPVRTRRRRKLYELHAAGAPPPPPPGHAPAPESPRPGS 773
PA PPG PP P + P PS + P L + P P P PE+P G
Sbjct: 1523 PAEPPGLPPASLPESTPIPSSSPP----------PLSSPLPEAPQPKEEPPVPEAPSSGP 1572
Query: 774 GSGS 777
S S
Sbjct: 1573 PSSS 1576
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 75.5 bits (184), Expect = 2e-13
Identities = 159/638 (24%), Positives = 222/638 (34%), Gaps = 148/638 (23%)
Query: 398 SLGSFQQQHTALQGPLASADLGLAPTPSPGLDRKALAEATNGEARAEPLAQNGGSSEPPA 457
++ S +QHT + + + G PT P AL A G+ + + +S P
Sbjct: 357 TIRSVAEQHTPVCSRFSPPEPGDTPTDEPD----ALYVACQGQPKGGHV-----TSMQPK 407
Query: 458 APRSIKVEA-------------VEEP--EAAPILGPGEPGPQAPSRTPSPRSPAPARVKA 502
P ++ EA +E P E P+L P E P +P SP SP P +A
Sbjct: 408 EPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPP---EA 464
Query: 503 ELSSPTP---GSSPVPGELGLAGAL----FLPQYVFGPDAAPPASEILAKMSELVHSRLQ 555
SP P +SP+P L L+ L P P + PP S + + E S +
Sbjct: 465 SRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPE 524
Query: 556 QGAGAGAGGAQTGLFPGAPKGATCFECEITFSNVNNYYVHKRLYCSGRRAPEDAPAARRP 615
+ + A +T L P P A +P P P
Sbjct: 525 ESPPSPA--LETPLSP--PPEA---------------------------SPLSPPFEESP 553
Query: 616 KAPPGPARAPPGQPAEPDAPRSSPGPGAREEGAGGAATPEDGAGGRGSEGS-------QS 668
+PP P P P P+A R SP P E + + PE+ E S +S
Sbjct: 554 LSPP-PEELPTSPP--PEASRLSPPP----EESPMSPPPEESPMSPPPEASRLFPPFEES 606
Query: 669 PGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPR-RPAAPPGPPGPA 727
P S E+ P E ASR PPP P +PP P
Sbjct: 607 PLS--PPPEESPLSPPPE--------------------ASRLSPPPEDSPMSPPPEESPM 644
Query: 728 APPAP-SPAAPVRTRRRRKLYELHAAGAPPPPPPGHAPAPESPRPGSGSGSGPGLAPARS 786
+PP S +P+ R + +PPP +P PE+ R P +P
Sbjct: 645 SPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSP-TSPPPE 703
Query: 787 PGPAADGPID------LSKKPRRPLPGAP--APALADYHECTACRVSFHSLEAYLA---H 835
PA+ P D L + P PLP P P H +S E +L+
Sbjct: 704 DSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPH------LSPRPEEPHLSPRPE 757
Query: 836 KKYSCPAAPPPGALGLPAAACPYCPPNGPVRGDLLEHFRLA---HGLLLGAPLAGPGVEA 892
+ + P A P P C P P E L+ L L P + +
Sbjct: 758 EPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHL-S 816
Query: 893 RTPADRGPSPAP----------APAASPQP-----GSRGPRDGLGPEPQEPPPGPPPSPA 937
P + SP P P SP+P + L P P++PP P P
Sbjct: 817 PVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCP- 875
Query: 938 AAPEAVP--PPPAPPSYS----DKGVQTPSKGTPAPLP 969
APE +P PPP PS S + + P + +PLP
Sbjct: 876 -APEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLP 912
Score = 55.5 bits (132), Expect = 3e-07
Identities = 141/565 (24%), Positives = 172/565 (30%), Gaps = 126/565 (22%)
Query: 453 SEPPAAPRSIKVEAVEEPEAAPILGPGEPGPQAPSRTPSPRSPAPARVKAELSSPTPGSS 512
S PPAA +I + + P G P A S P P SP +K L P
Sbjct: 2115 SPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGS-VPGPDSPGELFLK--LPPQVPAQV 2171
Query: 513 PVPGELGLAGALFL-PQYVFGPDAAPPASEILAKMSELVHSRLQQGAGAGAGGAQTGLFP 571
P GLA A L P++ P PP ++ GA + G Q G F
Sbjct: 2172 PSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPP----MLGASSRPGAGQPGEFH 2227
Query: 572 GAPKGATCFECEITFSNVNNYYVHKRLYCSGRRAPEDAPAARRPKAPPGPARAPPGQPA- 630
P G R P +P+ P A P P
Sbjct: 2228 TTPPGTP------------------------RHQPSTPDPFLKPRCPSLDNLAVPESPGV 2263
Query: 631 ---EPDAPRSSPGPGAREEGAG-------GAATPEDGAGGRGSEGSQSPGSSVDDAEDDP 680
+ P SP P A GA++P G G S S G+ + E
Sbjct: 2264 GGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKT 2323
Query: 681 SRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRPAAPPGPPGPAAPPAPSPAAPVRT 740
R AS+ +P P P PA APSP +
Sbjct: 2324 PDVFKAPLTPR---------------ASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDI 2368
Query: 741 RRRRKLYELHA------AGAPPPP------PPGHAPA------PESPRPGSGSGS----G 778
R + +A PPPP PP P+ P SP+ S S S
Sbjct: 2369 FRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPR 2428
Query: 779 PGLAPARSPGPAA---DGPIDLSKKPRRPLPGAPAPALADYHECTACRVSFHSLEAYLAH 835
P A A P P P S+ P RP P L V+F + LAH
Sbjct: 2429 PLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKA--GSLAH 2486
Query: 836 KKYSC---PAAPPPGALGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGPGVEA 892
PAA P G G A P P VR G +G P P
Sbjct: 2487 TSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSP-------GTGAFVGTP--SPMRFT 2537
Query: 893 RTPADRGPS---PAPAPAASPQPGSR---GPRDGLGPEPQEP----------PPGPPPSP 936
A PS P P P P G GP LG +PQ P G P P
Sbjct: 2538 FPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLG-KPQSTNYTVATGNFHPSGSPLGP 2596
Query: 937 AAA------------PEAVPPPPAP 949
++ P +V PPPAP
Sbjct: 2597 SSGSTGESYGLSPLRPPSVLPPPAP 2621
Score = 55.5 bits (132), Expect = 3e-07
Identities = 184/780 (23%), Positives = 274/780 (35%), Gaps = 153/780 (19%)
Query: 40 PEAPSPPSADVNSPP-----PLPPPTSPGGPKELEGQEPEPR---PTEEE-----PGSPW 86
P P+PP A P P PPP+SP PK Q P P PTE + PG+P
Sbjct: 4287 PRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKR-PSQLPSPSSQLPTEAQLPPTHPGTPK 4345
Query: 87 SGPDELEPV---VQDGQRRIRARLSLATGLS-WGPFHGSVQTRASSPRQAEPSPALTLLL 142
LEP V ++ L + GL W P +T+ P Q+ P
Sbjct: 4346 PQGPTLEPPPGRVSPAAAQLADTL-FSKGLGPWDPPDNLAETQ--KPEQSSLVPGH---- 4398
Query: 143 VDEACWLRTLPQALTEAEANTEIHRKDDALWCRVTK------PVPAGGLLSVLLTAEPHS 196
+D+ + +P+A ++ E + AL + K P+ A G + LL A P S
Sbjct: 4399 LDQVNG-QVVPEA-SQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHLLLAGPRS 4456
Query: 197 TPGHPVKKEPAEPTCPAPAHDLQLLPQQAGMASILATAVINKDVFPCKDCGIWYRSERNL 256
GH + ++ A ++QL G S A IN + K G+ E+ L
Sbjct: 4457 EAGHLLLQKLLR------AKNVQL---STGRGSEGLRAEINGHI-DSKLAGL----EQKL 4502
Query: 257 QAHLLYYCASRQGTGSPAAAATDEKPKETYPNERVCPFPQCRKSCPSASSLEIHMRSHSG 316
Q GT S A KP P + +K+ S +R G
Sbjct: 4503 Q-----------GTPSNKEDAAARKPLTPKPK-------RVQKASDRLVSSRKKLRKEDG 4544
Query: 317 ERPFVCLI----------------CLSAFTTKANCERHLKVHTDTLSGVCHSCGFISTTR 360
R L+ + F+ A V+ + G + T
Sbjct: 4545 VRASEALLKQLKQELSLLPLTEPAITANFSLFAPFGSGCPVNGQSQLRGAFGSGALPTGP 4604
Query: 361 DILYSHLVTNHMVCQPGSKGEIYSPGAGHPATKLPPDSLGSFQQQHTALQGPLASADLGL 420
D YS L+T + + P + P + LPP S QQ+ + G S +LG
Sbjct: 4605 DY-YSQLLTKNNLSNPPT-----------PPSSLPPTPPPSVQQK--MVNGVTPSEELGE 4650
Query: 421 APTPSPGLDRKALAEATNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILGPGE 480
P + A E ++ L + P +++E+ E+ ++ + P
Sbjct: 4651 HPKDAASARDSERALRDTSEVKSLDLLA-ALPTPPHNQTEDVRMESDEDSDSPDSIVPAS 4709
Query: 481 PGPQAPSRTPSPRSPAPARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGPDAAPPAS 540
P++ +PR P + E SPV + L +P + PD P +
Sbjct: 4710 -SPESILGEEAPRFPHLGSGRWEQEDRA--LSPV---IPLIPRASIPVF---PDTKPYGA 4760
Query: 541 EILAKMSELVHSRLQQGAGAGAGGAQTGLFPGAPKGATCFECEITFSNVNNYYVHKRLYC 600
L +L + ++G G+ T A N+N V
Sbjct: 4761 LGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAAA-------------KNLNGVMVAVAELL 4807
Query: 601 SGRRAPEDAPAARRPKAPPGPARAPPGQPAEPDAPRSSPGPGAREEGAGGAATPEDGAGG 660
S + P + P PARA +P + +A GPG +E+G G + P+ G
Sbjct: 4808 SMK-----IPNSYEVLFPESPARAGT-EPKKGEAE----GPGGKEKGLEGKS-PDTGPDW 4856
Query: 661 RGSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHD------PPP 714
+ PG ++ D S E+ E T H Y S D PPP
Sbjct: 4857 LKQFDAVLPGYTLKSQLDILSLLKQES-----PAPEPPTQHSYTYNVSNLDVRQLSAPPP 4911
Query: 715 RRPAAPPGPPGPAAPPAPSPAAPVRTRRRRKLYELHAAGAPPPPPPGHAP---APESPRP 771
P+ PP +P APSPA+P L EL PP P P +PES RP
Sbjct: 4912 EEPSPPP------SPLAPSPASP----PTEPLVELPTEPLAEPPVPSPLPLASSPESARP 4961
Score = 51.2 bits (121), Expect = 5e-06
Identities = 143/639 (22%), Positives = 201/639 (31%), Gaps = 99/639 (15%)
Query: 376 PGSKGEIYSPGAGHPATKLPPDSLGSFQQQHTALQGPLASADLGLAPTPSPGLDRKALAE 435
P ++ P P + P +S S + + L P + + P SP ++
Sbjct: 593 PPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVS- 651
Query: 436 ATNGEARAEPLAQNGGSSEPPA----APRSIKVEAVEEPEAAPILGPGEPGPQAPSRTPS 491
R PL S PP +P + PEA+ + P E P +P S
Sbjct: 652 ------RLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDS 705
Query: 492 PRSPAPARVKAELSSPTPGSSPVPGELGLAGALFLPQYVFGPDAAP-PASEILAKMSELV 550
P SP P L P+P E L P+ GP +P P L+ E
Sbjct: 706 PASPPPEDSLMSLPLEESPLLPLPEEPQLC-----PRSE-GPHLSPRPEEPHLSPRPEEP 759
Query: 551 HSRLQQGAGAGAGGAQTGLFPGAPKGATCFECEITFSNVNNYYVH-----KRLYCSGR-R 604
H Q + L P + C E + H + L+ S +
Sbjct: 760 HLSPQ--------AEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTE 811
Query: 605 APEDAPAARRPKAPPGPARAPPG-QPAEP---------------DAPRSSPGPGAREEGA 648
P +P P P P + Q EP + P SP P E
Sbjct: 812 EPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEP 871
Query: 649 GGAATPED----GAGGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRY 704
G PE+ G S ++ + + P L E + S + +
Sbjct: 872 GQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLM- 930
Query: 705 YCASRHDPPPRRPAAPPGPP--GPAAPPAPSPAAPVRTRRRRKLYELHAAGAPPPPPPGH 762
P P PP P AAPPA SP + Y A G P P
Sbjct: 931 ---------PPDPLPPPLSPIITAAAPPALSPLGELE-------YPFGAKGDSDPESPLA 974
Query: 763 APAPESPRPGSGSGSGPGLAPARSPGPAADGPIDLSKKPRRPLPGAPAPALADYHECTAC 822
AP E+P S P A P P P+ L P P+ G +P L +
Sbjct: 975 APILETPI------SPPPEANCTDPEPVP--PMILPPSPGSPV-GPASPILMEPLPPQCS 1025
Query: 823 RVSFHSLEAYLAHKKYSCPAAPPPGALGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLG 882
+ HSL + +PP L +P+ P G L
Sbjct: 1026 PLLQHSL---VPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPE 1082
Query: 883 APLAGPGVEARTPADRG----PSPAPAPAASPQPG---SRGPRDGLGPEPQEPPPGPPPS 935
P P + P+ G P+P+PAPA G P DG+ +P PG P
Sbjct: 1083 CPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPG 1142
Query: 936 PAA-----APEAVPP----PPAPPSYSDKGVQTPSKGTP 965
A +P + P P P + QT +G+P
Sbjct: 1143 SLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSP 1181
Score = 50.1 bits (118), Expect = 1e-05
Identities = 148/634 (23%), Positives = 194/634 (30%), Gaps = 110/634 (17%)
Query: 375 QPGSKGEIYSPGAGHPAT--KLPPDSLGSFQQQHTALQGPLASADLGLAPTPSPGL---- 428
QP G PGAG P PP + P + LA SPG+
Sbjct: 2208 QPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGK 2267
Query: 429 -DRKALAEATNGEARA--EPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILG-------- 477
L+ GE+R E + G+S P P ++ V+ P + LG
Sbjct: 2268 ASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGF--VDSPSSGTHLGGLELKTPD 2325
Query: 478 ---------PGEPGPQAPSRTPSPRSPAPARVKAELSSPTPGSSPV---PGELGLAGALF 525
+ PQ+P P+ P PA+ A P+P S P PG
Sbjct: 2326 VFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALA----PSPPSHPDIFRPGSY--TDPYA 2379
Query: 526 LPQYVFGPDAAPPASEILAKMSELVHSRLQQ--GAGAGAGGAQTGLFPGAPKGATCFECE 583
P P PP S L + + +Q+ L P P A F C
Sbjct: 2380 QPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTP-RPLSAEAF-CP 2437
Query: 584 ITFSNVNNYYVHKRLYCSGRRAPEDAPAARRPKAPPGPARAPPGQPAEPDAPRSSPGPGA 643
S V + Y P P +R P AP PP +P P+ +
Sbjct: 2438 ---SPVTPRFQSPDPYSR----PPSRPQSRDPFAP---LHKPP-RPQPPEVAFKAGSLAH 2486
Query: 644 REEGAGG--AATPEDGAG--------GRGSEGSQSPGSSVDDAEDDPSRTLCEACNIRFS 693
GAGG AA P AG G+ +SPG+ P R
Sbjct: 2487 TSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMR----------- 2535
Query: 694 RHETYTVHKRYYCASRHDPPPRRPAAPPGPPGPAAPPAPSPAAPVRTRRRRKLYELHAAG 753
+T + S P P+ PP P P+ P T H +G
Sbjct: 2536 ----FTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSG 2591
Query: 754 APPPPPPGHAPAPESPRPGSGSGSGPGLAPARSPGPAADGPIDLSKKPRRPLPGAPAPAL 813
+P P G G G P P+ P PA DG + G +P
Sbjct: 2592 SPLGPSSGST--------GESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVE 2643
Query: 814 ADYHECTACRVSFHSLEAYLAHKKYSCPAAPPPGALGLPAAACPYCPPNGPVRGDLLEHF 873
T S + E P PG GL +R +LL
Sbjct: 2644 KREDPGTGMGSSLATAE---------LPGTQDPGMSGLSQTELEKQRQRQRLR-ELLIRQ 2693
Query: 874 RLAHGLL--------LGAPLAGP----GVEARTPADRGPSPAPAPAASPQPGSRGPRDGL 921
++ L A GP G E +PA S P A Q + GL
Sbjct: 2694 QIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQ--DKSSLVGL 2751
Query: 922 GPEPQEPP-PGPPPSPAAAPEAVPPPPAPPSYSD 954
P P GP P+ + PPPPA PS D
Sbjct: 2752 PPSKLSGPILGPGSFPSDDRLSRPPPPATPSSMD 2785
Score = 49.7 bits (117), Expect = 1e-05
Identities = 178/731 (24%), Positives = 231/731 (31%), Gaps = 181/731 (24%)
Query: 344 DTLSGVCHSCGFISTTRDILYSHLVTNHMVCQPGSKGEIYSPGAGHPATKL---PPDSLG 400
D+ S H G T D+ + L +P S G P PA L PP
Sbjct: 2308 DSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPD 2367
Query: 401 SFQQQHTALQGPLASADLGLAPTPSP-----GLDRKALAEATNGEARAEPLAQNGGSSEP 455
F+ + P A L P P P L ++L A P +Q+ SS+
Sbjct: 2368 IFRPG--SYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQS--SSQS 2423
Query: 456 PAAPRSIKVEAVEEPEAAPILGPGEPGPQAPSRTPSPRSPAPARVKAELSSPTPGSSPVP 515
P PR + EA P +P + PSR P R P A L P P P
Sbjct: 2424 PLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSR-PQSRDPF-----APLHKP---PRPQP 2474
Query: 516 GELGL-AGALFLPQYVFG--PDAAP--PASEILAKMSELVHSRLQQGAGAGA-------- 562
E+ AG+L G P A P PA E+ AK+ + G GA
Sbjct: 2475 PEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPM 2534
Query: 563 ------GGAQTGLFPGAPK---------------GATCFECEITFSNVNNYYVHKRLYCS 601
+ L P P+ G T + + T NY V +
Sbjct: 2535 RFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQST-----NYTV-----AT 2584
Query: 602 GRRAPEDAPA-----------ARRPKAPPG--PARAPPGQPAEPDAPRSSPGPGAREEGA 648
G P +P P PP P AP G P S G R
Sbjct: 2585 GNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDG-----SLPYLSHGASQRSGIT 2639
Query: 649 GGAATPEDGAGGRGSE-------GSQSPG-SSVDDAEDDPSR---TLCEACNIRFSRHET 697
ED G GS G+Q PG S + E + R L E + + T
Sbjct: 2640 SPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNT 2699
Query: 698 YTVHKRYYCASRHDPPPRRPAAPPGPPGPAAPPAPSPAAPVRTRRRRKLYELHAAGAPPP 757
K A+ A GPPG SPA +R + +
Sbjct: 2700 LRQEKETAAAA---------AGAVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVG 2750
Query: 758 PPPGHAPAPESPRPGSGSGSGPGLAP-----ARSPGPAADGPIDLSKK----------PR 802
PP SG GPG P +R P PA +D++ + R
Sbjct: 2751 LPPSKL---------SGPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQR 2801
Query: 803 RPLPGAPAPALADYHECTACRVSFHSLEAYLAHKKYSCPAAPPPGALGLPAAACPYCPPN 862
P PG+ + + L ++ + A A+ +A P P
Sbjct: 2802 APYPGS---------------LPLQQQQQQLWQQQQATAATSMRFAM---SARFPSTP-- 2841
Query: 863 GPVRGDLLEHFRLAHGLLLGAPLAGPGVEARTPADRGPSPAPAPAASPQPGSRGPRDGLG 922
GP G R A LG+PLA G+ R P P P PA A + GLG
Sbjct: 2842 GPELG------RQA----LGSPLA--GISTRLPGPGEPVPGPAGPAQFIELRHNVQKGLG 2889
Query: 923 PEPQE-PPPGPPPSP----------AAAPE--------AVPP--PPAPPSYSDKGVQTPS 961
P P GPP P APE +PP P APP+ P+
Sbjct: 2890 PGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSLHPT 2949
Query: 962 KGTPAP-LPNG 971
T P LP G
Sbjct: 2950 PHTKGPTLPTG 2960
Score = 48.9 bits (115), Expect = 2e-05
Identities = 101/395 (25%), Positives = 125/395 (31%), Gaps = 82/395 (20%)
Query: 612 ARRPKAPPGPARAPPGQPAEPDAPRSSPGPGAREEGAGGAATPEDGAG-GRGSEGSQSPG 670
AR+ P R PP +P A S P A G TP AG ++G P
Sbjct: 2094 ARKTDRPALHLRIPP----QPGALGSPPPAAAPTIFIGSPTTP---AGLSTSADGFLKPP 2146
Query: 671 SSVDDAEDDPSRTLCEACNIRFSRHETYTVHKR--YYCASRHDPPPRRPAAPPGPPGPAA 728
+ D P ++ V + + A + PR P APP
Sbjct: 2147 AGSVPGPDSPGELF-----LKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPP-----TY 2196
Query: 729 PPAPSPAAPVRTRRRRKLYELHAAGAPPPPPPGHAPAPESPRPGSGSGSGPGLAPARSPG 788
PP PSP GAP PP A S RPG+G PG PG
Sbjct: 2197 PPYPSPT-----------------GAPAQPPMLGA----SSRPGAGQ---PGEFHTTPPG 2232
Query: 789 PAADGPI--DLSKKPRRP------LPGAPAPALADYHECTACRVSFHSLEAYLAHKKYSC 840
P D KPR P +P +P E F L KK
Sbjct: 2233 TPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEEL 2292
Query: 841 PAAPPPGALGLPAAACPYCPPN-----GPVRGDLLEHFRLAHGLLLGAPLA--GPGVEAR 893
A+ P Y PPN P G L L + APL VE +
Sbjct: 2293 GASSPS-----------YGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQ 2341
Query: 894 TPAD--RGPSPAPAPAASPQPGSRGP-------RDGLGPEPQEPPPGPPPSP---AAAPE 941
+P R P PA A +P P S D P P P PPP A P
Sbjct: 2342 SPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPR 2401
Query: 942 AVPPPPAPPSYSDKGVQTPSKGTPAPLPNGNHRYC 976
++P P + Q+ S+ P P +C
Sbjct: 2402 SLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFC 2436
Score = 47.8 bits (112), Expect = 5e-05
Identities = 184/815 (22%), Positives = 261/815 (32%), Gaps = 127/815 (15%)
Query: 31 SHMEQKATAPEAPSPPSADVN---SPPPLPPPTSPGGPKELEGQEPEPRPTEEEP-GSPW 86
S +E+ +P SPPS + SPPP P SP + PE PT P S
Sbjct: 513 SPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRL 572
Query: 87 SGPDELEPVVQDGQRRIRARLSLATGLSWGPFHGSVQTRASSPRQAEPSPALTLLLVDEA 146
S P E P+ + + A+ L + PF S + P P + L
Sbjct: 573 SPPPEESPMSPPPEESPMSPPPEASRL-FPPFEESPLSPPPEESPLSPPPEASRLSPPPE 631
Query: 147 CWLRTLPQALTEAEANTEIHRKDDALWCRVTKPVPAGGLLSVLLTAEPHSTPGHPVKKEP 206
+ P + E+ R P P LS P S P + P
Sbjct: 632 DSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSP 691
Query: 207 A---EPTCPAPAHDLQLLPQQAGMASILATAVINKDVFPC-KDCGIWYRSERNLQAHLLY 262
PT P P P + S+++ + + P ++ + RSE HL
Sbjct: 692 PPEDSPTSPPPEDSPASPPPE---DSLMSLPLEESPLLPLPEEPQLCPRSE---GPHL-- 743
Query: 263 YCASRQGTGSPAAAATDEKPKETYPNERVCPFPQCRKSCPSASSLEIHMRSHSGERPFVC 322
P + E+P + E PQ + C A E H+ S E P +
Sbjct: 744 ----SPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHL-SPQAEGPHL- 797
Query: 323 LICLSAFTTKANCERHLKVHTDT--LSGVCHSCGFISTTRDILYSHLVTNHMVCQPGSKG 380
+ E HL T+ LS V + SHL P S+
Sbjct: 798 --------SPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEE---SHL-------SPQSEE 839
Query: 381 EIYSPGAGH----PATKLPPDSLGSFQQQHTALQGPLASADLGLAPTP-----SPGLDRK 431
SP P + PP S + Q P A +L L P P SP L
Sbjct: 840 PCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCP-APEELPLFPPPGEPSLSPLLGEP 898
Query: 432 ALAEATNGEARAEPLAQN---GGSSEPPAAPRSIKVEAVEEP-------EAAPILGP--- 478
AL+E GE PL + S EP +P+ + + + P A P L P
Sbjct: 899 ALSEP--GEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGE 956
Query: 479 --------GEPGPQAPSRTPSPRSPAPARVKAELSSPTPGSSPVPGELGLAGALFLPQYV 530
G+ P++P P +P +A + P PVP + LP
Sbjct: 957 LEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDP----EPVP-------PMILPPSP 1005
Query: 531 FGPDAAPPASEIL-----AKMSELVHSRLQQGAGAGAGGAQTGLFPGAPKGATCFECEIT 585
P PAS IL + S L+ L + + L P + +
Sbjct: 1006 GSP--VGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVG 1063
Query: 586 FSNVNNYYVHKRLYCSGRRAPEDAPAARRPKAPPGPARAPPGQPAEPDAPRSSPGPGARE 645
S+ + + S P P+A P P + P SP P +
Sbjct: 1064 VSDEAELHEMETEKVSEPECPALEPSATSPL---------PSPMGDLSCPAPSPAPALDD 1114
Query: 646 -EGAGGAATPEDGAGGRGS--EGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHK 702
G G P DG GS E Q+PGS + + P + E V
Sbjct: 1115 FSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASELKGSP---------VLLDPEELAPV-- 1163
Query: 703 RYYCASRHDPPPRRPAAPPGPP-----GPAAPPAPSPAAPVRTRRRRKLYELHAAGAPPP 757
P + A G P P AP AP+P +++ ++ L + G
Sbjct: 1164 ----TPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPPTLIKSDIVNEISNL-SQGDASA 1218
Query: 758 PPPGHAPAPESPRPGSGSGSGPGLAPARSPGPAAD 792
PG P SP P G L + PA D
Sbjct: 1219 SFPGSEPLLGSPDPEGGGSLSMELGVSTDVSPARD 1253
Score = 38.1 bits (87), Expect = 0.042
Identities = 42/138 (30%), Positives = 55/138 (39%), Gaps = 16/138 (11%)
Query: 5 KQSNPRQIK-RSLGDMEAREEVQLVGASHMEQKATAPEAPSPPSADVNSPPPLPPPTSPG 63
K+ P Q + + LG + E QL + E P SP S PPP PTSP
Sbjct: 407 KEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLS-----PPPEESPTSP- 460
Query: 64 GPKELEGQEPEPRPTEEEPGSPWSGPDEL---EPVVQDGQRRIRARLSLATGLSWGPFHG 120
P E P P EE P SP P+ L P+ + L+ PF
Sbjct: 461 -PPEASRLSP---PPEELPASPL--PEALHLSRPLEESPLSPPPEESPLSPPPESSPFSP 514
Query: 121 SVQTRASSPRQAEPSPAL 138
++ S P ++ PSPAL
Sbjct: 515 LEESPLSPPEESPPSPAL 532
Score = 37.4 bits (85), Expect = 0.071
Identities = 23/55 (41%), Positives = 27/55 (49%), Gaps = 2/55 (3%)
Query: 895 PADRGPSPAPAPAA-SPQPGSRGPRDGLGPEPQEPPPGPPPSP-AAAPEAVPPPP 947
P PSP P+P A SP P L EP PP P P P A++PE+ P P
Sbjct: 4909 PPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKP 4963
Score = 37.0 bits (84), Expect = 0.093
Identities = 48/183 (26%), Positives = 63/183 (34%), Gaps = 43/183 (23%)
Query: 763 APAPESPRPGSGSGSGPGLAPARSPGPAADGPIDLSKKPRRPLPG--------------- 807
+PA P G GPG G + D D K+ LPG
Sbjct: 4822 SPARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQLDILSLLKQ 4881
Query: 808 -APAPALADYHECTACRVSFHSLEAYLAHKKYSCPAAPPPGALGLPAAACPYCPPNGPVR 866
+PAP H T + +L+ ++ S P P P A P PP P
Sbjct: 4882 ESPAPEPPTQHSYT---YNVSNLDV----RQLSAPPPEEPSPPPSPLAPSPASPPTEP-- 4932
Query: 867 GDLLEHFRLAHGLLLGAPLAGPGVEARTPADRGPSPAPAPAASPQPGSRGPRDGLGPEPQ 926
L+E L PLA P V + P P +A P+P +R P +G E
Sbjct: 4933 --LVE--------LPTEPLAEPPVPSPLPLASSPE-----SARPKPRARPPEEG---EDS 4974
Query: 927 EPP 929
PP
Sbjct: 4975 RPP 4977
Score = 36.6 bits (83), Expect = 0.12
Identities = 28/89 (31%), Positives = 32/89 (35%), Gaps = 10/89 (11%)
Query: 884 PLAGPGVEART-PADRGPSPAPAPAASPQPGSRGPRDGLGPEPQEPPPGPPPSPAAAPEA 942
P GP E P +GP PAP PG+ LGP PPP P P +
Sbjct: 4269 PQTGPLQELGAGPRPQGPPRLPAP-----PGALSTGPVLGPVHPTPPPSSPQEPKRPSQL 4323
Query: 943 VPPPPAPPSYSDKGVQTPSKGTPAPLPNG 971
P+P S Q P P P G
Sbjct: 4324 ----PSPSSQLPTEAQLPPTHPGTPKPQG 4348
Score = 35.4 bits (80), Expect = 0.27
Identities = 52/197 (26%), Positives = 65/197 (32%), Gaps = 24/197 (12%)
Query: 399 LGSFQQQHTALQGPLASADLGLAPTPSPGLDRKALAEATNGEARAEPLAQNGGSSEPPAA 458
LG F T GPL G P P L A +T S + P
Sbjct: 4263 LGGFPGPQT---GPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKR 4319
Query: 459 PRSIKVEAVEEPEAA--PILGPGEPGPQAPSRTPSPR--SPAPARVKAELSSPTPG---- 510
P + + + P A P PG P PQ P+ P P SPA A++ L S G
Sbjct: 4320 PSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDP 4379
Query: 511 ------------SSPVPGELGLAGALFLPQYVFGPDAAPPASEILAKMSELVHSRLQQGA 558
SS VPG L +P+ P E A ++ V R G
Sbjct: 4380 PDNLAETQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSV-KREANGE 4438
Query: 559 GAGAGGAQTGLFPGAPK 575
GA G L P+
Sbjct: 4439 PIGAPGTSNHLLLAGPR 4455
Score = 34.3 bits (77), Expect = 0.61
Identities = 30/96 (31%), Positives = 34/96 (35%), Gaps = 16/96 (16%)
Query: 720 PPGPPGPAAPPAPSPAAPVRTRRRRKLYELHAAGAPPPPPPGHAPAP-ESPRPGSGSGSG 778
P GPP APP PV L +H PPP P P + P P S +
Sbjct: 4283 PQGPPRLPAPPGALSTGPV-------LGPVHP--TPPPSSPQEPKRPSQLPSPSSQLPTE 4333
Query: 779 PGLAPARSPGPAADGPIDLSKKPRRPLPGAPAPALA 814
L P P GP P PG +PA A
Sbjct: 4334 AQLPPTHPGTPKPQGP------TLEPPPGRVSPAAA 4363
Score = 33.1 bits (74), Expect = 1.3
Identities = 58/214 (27%), Positives = 72/214 (33%), Gaps = 46/214 (21%)
Query: 759 PPGHAPAPESPRPGSGSGSGPGLAPARSPGPAADGPIDLSKKPRRPLPGAPAPALADYHE 818
P + P+ P+PG SG GL PG G + + R L G A H
Sbjct: 4163 PMQNNTGPQPPKPGPVLQSGQGL-----PGV---GIMPTVGQLRAQLQGVLAKNPQLRHL 4214
Query: 819 CTACRVSFHSLEAYLAHKKYSCPAA----PP---PGALGLPAAACPYCPPN-----GPVR 866
+ L+A L ++ A PP PG P C P GP
Sbjct: 4215 SPQQQ---QQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQT 4271
Query: 867 GDLLE-----------HFRLAHGLLLGAPLAGPGVEARTPADRGPSPAPAPAASPQPGSR 915
G L E G L P+ GP TP P P+ P P S+
Sbjct: 4272 GPLQELGAGPRPQGPPRLPAPPGALSTGPVLGP--VHPTPPPSSPQEPKRPSQLPSPSSQ 4329
Query: 916 GPRDGL-------GPEPQEPPPGPPP---SPAAA 939
P + P+PQ P PPP SPAAA
Sbjct: 4330 LPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAA 4363
Score = 33.1 bits (74), Expect = 1.3
Identities = 26/85 (30%), Positives = 30/85 (35%), Gaps = 8/85 (9%)
Query: 730 PAPSPAAPVRTRRRRKLYELHAAGAPPPPPPGHAPAPESPRPGSGSGS------GPGLA- 782
PAP P ++ APPP P P+P +P P S LA
Sbjct: 4884 PAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAE 4943
Query: 783 -PARSPGPAADGPIDLSKKPRRPLP 806
P SP P A P KPR P
Sbjct: 4944 PPVPSPLPLASSPESARPKPRARPP 4968
Score = 32.3 bits (72), Expect = 2.3
Identities = 102/434 (23%), Positives = 136/434 (31%), Gaps = 82/434 (18%)
Query: 492 PRSPAPARVKAELSSPTPGSS--------PVPGELGLAGALFLPQYV---FGPDAAP--- 537
P +P P + L SP G S PVPG G A + L V GP P
Sbjct: 2838 PSTPGPELGRQALGSPLAGISTRLPGPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPG 2897
Query: 538 ---PASEILAKMSELVHSRLQQGAGAGAGGAQTGLFPGAPKGATCFECEITFSNVNNYYV 594
P +SE H +G G A +GL P P E N +
Sbjct: 2898 QGPPQRPRFYPVSEDPHRLAPEGL---RGLAVSGLPPQKPSAPPAPEL--------NNSL 2946
Query: 595 HKRLYCSGRRAPEDAPAARRPKAP-----PGPARAPPGQ-PAE-PDAPRSSPGPGAREE- 646
H + G P RP + P P G+ P E P+ A E+
Sbjct: 2947 HPTPHTKGPTLPTGLELVNRPPSSTELGRPNPLALEAGKLPCEDPELDDDFDAHKALEDD 3006
Query: 647 ------GAGGAATPEDGAGGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIRFS---RHET 697
G G D G E ++ +DD + L + + +
Sbjct: 3007 EELAHLGLGVDVAKGDDELGT-LENLETNDPHLDDLLNGDEFDLLAYTDPELDTGDKKDI 3065
Query: 698 YTVHKRYYCASRHDPPPRRP---AAPPGPPGPAAPPAPSPAAPVRTRRRRKLYELHAAGA 754
+ H R S ++ R PGP GP P P+ A E A
Sbjct: 3066 FNEHLRLV-ESANEKAEREALLRGVEPGPLGPEERPPPAADAS----------EPRLASV 3114
Query: 755 PPPPPPGHAPAPESPRPGSGSGSGPGLAPARSPGPAADGPIDLSKKPRRPLPGAPAPALA 814
P P P P + + P + PA PAA+ + L KP + + G+
Sbjct: 3115 LPEVKPKVEEGGRHPSPCQFTIATPKVEPA----PAANS-LGLGLKPGQSMMGS------ 3163
Query: 815 DYHECTACRVSFHSLEAYLAHKKYSCPAAPPPGALGLPAAACPYCPPNGPVRGDLLEHFR 874
T S + A K PP L P+ P +GP LLE F
Sbjct: 3164 ---RDTRMGTGPFSSSGHTAEKASFGATGGPPAHLLTPS------PLSGPGGSSLLEKFE 3214
Query: 875 LAHGLLL--GAPLA 886
L G L G P A
Sbjct: 3215 LESGALTLPGGPAA 3228
Score = 32.3 bits (72), Expect = 2.3
Identities = 23/72 (31%), Positives = 28/72 (38%), Gaps = 6/72 (8%)
Query: 901 SPAPAPAASPQ----PGSRGPRDGLGPEPQEPPPGPPPSPAAAPEAVPPPPAPPSYSDKG 956
SPAP P + R P P+EP PPPSP A A PP +
Sbjct: 4883 SPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEP--SPPPSPLAPSPASPPTEPLVELPTEP 4940
Query: 957 VQTPSKGTPAPL 968
+ P +P PL
Sbjct: 4941 LAEPPVPSPLPL 4952
Score = 30.8 bits (68), Expect = 6.7
Identities = 27/90 (30%), Positives = 32/90 (35%), Gaps = 4/90 (4%)
Query: 7 SNPRQIKRSLGDMEAREEVQLVGASHMEQKATAPEAPSPPSADVNSPPPLPPPTSPGGPK 66
S P + R E L A H+ + PP SPPP P SP
Sbjct: 459 SPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEES 518
Query: 67 ELEG-QEPEPRPTEEEPGSPWSGPDELEPV 95
L +E P P E P SP P E P+
Sbjct: 519 PLSPPEESPPSPALETPLSP---PPEASPL 545
Score = 30.8 bits (68), Expect = 6.7
Identities = 37/139 (26%), Positives = 47/139 (33%), Gaps = 22/139 (15%)
Query: 403 QQQHTALQGPLASADLGLAPTPS--------PGLDRKALAEATNGEARAEPLAQNGGSSE 454
QQQ G L + L+P PG+ K L ++ A L G E
Sbjct: 3968 QQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTG--KE 4025
Query: 455 PPAAPRSIKVEAVEEPEAAPILGPGEPGPQAPSRTPSPRSPAPARVKAELSSPT------ 508
++ EA E P + GP A TP + P VK LS +
Sbjct: 4026 QNTVDPAVSSEATEGPSTH------QGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQ 4079
Query: 509 PGSSPVPGELGLAGALFLP 527
P P P L L L LP
Sbjct: 4080 PQPQPQPSSLQLQPPLRLP 4098
Score = 30.8 bits (68), Expect = 6.7
Identities = 37/153 (24%), Positives = 47/153 (30%), Gaps = 18/153 (11%)
Query: 379 KGEIYSPGAGHPAT--KLPPDSLGSFQQQHTALQGPLASADLGL-------APTPSPGLD 429
KGE PG K P +Q L G + L + +P P P
Sbjct: 4832 KGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQ 4891
Query: 430 RKALAEATNGEARAEPLAQNGGSSEPPA----APRSIKVEAVEEPEAAPILGPGEPGPQA 485
+N + R S PP+ +P S E + E P+ P P P
Sbjct: 4892 HSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSP-- 4949
Query: 486 PSRTPSPRSPAPARVKAELSSPTPGSSPVPGEL 518
P SP AR K P G P L
Sbjct: 4950 ---LPLASSPESARPKPRARPPEEGEDSRPPRL 4979
Score = 30.8 bits (68), Expect = 6.7
Identities = 34/136 (25%), Positives = 46/136 (33%), Gaps = 30/136 (22%)
Query: 26 QLVGASHMEQKATAPEAP-----------------SPPSADVNSPPPLPPPTSPGGPKE- 67
QL S ++Q++ APE P S P + SPPP P SP P
Sbjct: 4872 QLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTE 4931
Query: 68 ----------LEGQEPEPRPTEEEPGSPWSGPDELEPVVQDGQRRIRARLSLATGLSWGP 117
E P P P P S P P ++G+ RL G+ W
Sbjct: 4932 PLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPP--EEGEDSRPPRLKKWKGVRWKR 4989
Query: 118 FHGSVQTRASSPRQAE 133
+ + S RQ +
Sbjct: 4990 LRLLLTIQKGSGRQED 5005
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.132 0.417
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 63,879,015
Number of Sequences: 37866
Number of extensions: 5225400
Number of successful extensions: 146141
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 2134
Number of HSP's successfully gapped in prelim test: 2476
Number of HSP's that attempted gapping in prelim test: 31276
Number of HSP's gapped (non-prelim): 65100
length of query: 1006
length of database: 18,247,518
effective HSP length: 112
effective length of query: 894
effective length of database: 14,006,526
effective search space: 12521834244
effective search space used: 12521834244
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.