Search of human proteins with 110431352

Search of human proteins with 110431352

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|110431352 transducer of regulated CREB protein 3 isoform b
[Homo sapiens]
         (618 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|110431352 transducer of regulated CREB protein 3 isoform b [H...  1253   0.0  
gi|110431354 transducer of regulated CREB protein 3 isoform a [H...  1248   0.0  
gi|32171215 CREB regulated transcription coactivator 2 [Homo sap...   337   3e-92
gi|148596965 mucoepidermoid carcinoma translocated 1 isoform 1 [...   283   3e-76
gi|148596988 mucoepidermoid carcinoma translocated 1 isoform 3 [...   278   1e-74
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    53   7e-07
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    52   2e-06
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    51   3e-06
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    50   6e-06
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ...    50   8e-06
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)...    50   8e-06
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)...    50   8e-06
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)...    50   8e-06
gi|105990535 coagulation factor V precursor [Homo sapiens]             49   1e-05
gi|239756297 PREDICTED: hypothetical protein [Homo sapiens]            49   1e-05
gi|50345997 E1A binding protein p300 [Homo sapiens]                    49   2e-05
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]               49   2e-05
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]     47   4e-05
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]     47   4e-05
gi|157739945 tetratricopeptide repeat, ankyrin repeat and coiled...    47   4e-05
gi|239745228 PREDICTED: hypothetical protein XP_002343392 [Homo ...    47   7e-05
gi|55750053 atrophin-1 [Homo sapiens]                                  47   7e-05
gi|55750041 atrophin-1 [Homo sapiens]                                  47   7e-05
gi|236459851 ubinuclein 2 [Homo sapiens]                               46   1e-04
gi|239750867 PREDICTED: hypothetical protein XP_002347588 [Homo ...    46   1e-04
gi|55953100 tubby like protein 4 isoform 1 [Homo sapiens]              45   2e-04
gi|33186895 selenoprotein V [Homo sapiens]                             45   3e-04
gi|112421108 capicua homolog [Homo sapiens]                            44   3e-04
gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]        44   4e-04
gi|237757326 synaptojanin 1 isoform d [Homo sapiens]                   44   4e-04

>gi|110431352 transducer of regulated CREB protein 3 isoform b [Homo
           sapiens]
          Length = 618

 Score = 1253 bits (3241), Expect = 0.0
 Identities = 618/618 (100%), Positives = 618/618 (100%)

Query: 1   MAASPGSGSANPRKFSEKIALHTQRQAEETRAFEQLMTDLTLSRVQFQKLQQLRLTQYHG 60
           MAASPGSGSANPRKFSEKIALHTQRQAEETRAFEQLMTDLTLSRVQFQKLQQLRLTQYHG
Sbjct: 1   MAASPGSGSANPRKFSEKIALHTQRQAEETRAFEQLMTDLTLSRVQFQKLQQLRLTQYHG 60

Query: 61  GSLPNVSQLRSSASEFQPSFHQADNVRGTRHHGLVERPSRNRFHPLHRRSGDKPGRQFDG 120
           GSLPNVSQLRSSASEFQPSFHQADNVRGTRHHGLVERPSRNRFHPLHRRSGDKPGRQFDG
Sbjct: 61  GSLPNVSQLRSSASEFQPSFHQADNVRGTRHHGLVERPSRNRFHPLHRRSGDKPGRQFDG 120

Query: 121 SAFGANYSSQPLDESWPRQQPPWKDEKHPGFRLTSALNRTNSDSALHTSALSTKPQDPYG 180
           SAFGANYSSQPLDESWPRQQPPWKDEKHPGFRLTSALNRTNSDSALHTSALSTKPQDPYG
Sbjct: 121 SAFGANYSSQPLDESWPRQQPPWKDEKHPGFRLTSALNRTNSDSALHTSALSTKPQDPYG 180

Query: 181 GGGQSAWPAPYMGFCDGENNGHGEVASFPGPLKEENLLNVPKPLPKQLWETKEIQSLSGR 240
           GGGQSAWPAPYMGFCDGENNGHGEVASFPGPLKEENLLNVPKPLPKQLWETKEIQSLSGR
Sbjct: 181 GGGQSAWPAPYMGFCDGENNGHGEVASFPGPLKEENLLNVPKPLPKQLWETKEIQSLSGR 240

Query: 241 PRSCDVGGGNAFPHNGQNLGLSPFLGTLNTGGSLPDLTNLHYSTPLPASLDTTDHHFGSM 300
           PRSCDVGGGNAFPHNGQNLGLSPFLGTLNTGGSLPDLTNLHYSTPLPASLDTTDHHFGSM
Sbjct: 241 PRSCDVGGGNAFPHNGQNLGLSPFLGTLNTGGSLPDLTNLHYSTPLPASLDTTDHHFGSM 300

Query: 301 SVGNSVNNIPAAMTHLGIRSSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASAL 360
           SVGNSVNNIPAAMTHLGIRSSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASAL
Sbjct: 301 SVGNSVNNIPAAMTHLGIRSSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASAL 360

Query: 361 HPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPT 420
           HPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPT
Sbjct: 361 HPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPT 420

Query: 421 SQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQ 480
           SQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQ
Sbjct: 421 SQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQ 480

Query: 481 SDFQLLPAQGSSLTNFFPDVGFDQQSMRPGPAFPQQVPLVQQGSRELQDSFHLRPSPYSN 540
           SDFQLLPAQGSSLTNFFPDVGFDQQSMRPGPAFPQQVPLVQQGSRELQDSFHLRPSPYSN
Sbjct: 481 SDFQLLPAQGSSLTNFFPDVGFDQQSMRPGPAFPQQVPLVQQGSRELQDSFHLRPSPYSN 540

Query: 541 CGSLPNTILPDSSTSLFKDLNSALAGLPEVSLNVDTPFPLEEELQIEPLSLDGLNMLSDS 600
           CGSLPNTILPDSSTSLFKDLNSALAGLPEVSLNVDTPFPLEEELQIEPLSLDGLNMLSDS
Sbjct: 541 CGSLPNTILPDSSTSLFKDLNSALAGLPEVSLNVDTPFPLEEELQIEPLSLDGLNMLSDS 600

Query: 601 SMGLLDPSVEETFRADRL 618
           SMGLLDPSVEETFRADRL
Sbjct: 601 SMGLLDPSVEETFRADRL 618


>gi|110431354 transducer of regulated CREB protein 3 isoform a [Homo
           sapiens]
          Length = 619

 Score = 1248 bits (3229), Expect = 0.0
 Identities = 618/619 (99%), Positives = 618/619 (99%), Gaps = 1/619 (0%)

Query: 1   MAASPGSGSANPRKFSEKIALHTQRQAEETRAFEQLMTDLTLSRVQFQKLQQLRLTQYHG 60
           MAASPGSGSANPRKFSEKIALHTQRQAEETRAFEQLMTDLTLSRVQFQKLQQLRLTQYHG
Sbjct: 1   MAASPGSGSANPRKFSEKIALHTQRQAEETRAFEQLMTDLTLSRVQFQKLQQLRLTQYHG 60

Query: 61  GSLPNVSQLRSSASEFQPSFHQADNVRGTRHHGLVERPSRNRFHPLHRRSGDKPGRQFDG 120
           GSLPNVSQLRSSASEFQPSFHQADNVRGTRHHGLVERPSRNRFHPLHRRSGDKPGRQFDG
Sbjct: 61  GSLPNVSQLRSSASEFQPSFHQADNVRGTRHHGLVERPSRNRFHPLHRRSGDKPGRQFDG 120

Query: 121 SAFGANYSSQPLDESWPRQQPPWKDEKHPGFRLTSALNRTNSDSALHTSALSTKPQDPYG 180
           SAFGANYSSQPLDESWPRQQPPWKDEKHPGFRLTSALNRTNSDSALHTSALSTKPQDPYG
Sbjct: 121 SAFGANYSSQPLDESWPRQQPPWKDEKHPGFRLTSALNRTNSDSALHTSALSTKPQDPYG 180

Query: 181 GGGQSAWPAPYMGFCDGENNGHGEVASFPGPLKEENLLNVPKPLPKQLWETKEIQSLSGR 240
           GGGQSAWPAPYMGFCDGENNGHGEVASFPGPLKEENLLNVPKPLPKQLWETKEIQSLSGR
Sbjct: 181 GGGQSAWPAPYMGFCDGENNGHGEVASFPGPLKEENLLNVPKPLPKQLWETKEIQSLSGR 240

Query: 241 PRSCDVGGGNAFPHNGQNLGLSPFLGTLNTGGSLPDLTNLHYSTPLPASLDTTDHHFGSM 300
           PRSCDVGGGNAFPHNGQNLGLSPFLGTLNTGGSLPDLTNLHYSTPLPASLDTTDHHFGSM
Sbjct: 241 PRSCDVGGGNAFPHNGQNLGLSPFLGTLNTGGSLPDLTNLHYSTPLPASLDTTDHHFGSM 300

Query: 301 SVGNSVNNIPAAMTHLGIRSSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASAL 360
           SVGNSVNNIPAAMTHLGIRSSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASAL
Sbjct: 301 SVGNSVNNIPAAMTHLGIRSSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASAL 360

Query: 361 HPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPT 420
           HPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPT
Sbjct: 361 HPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPT 420

Query: 421 SQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQ 480
           SQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQ
Sbjct: 421 SQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQ 480

Query: 481 SDFQLLPAQGSSLTNFFPDVGFDQQSMRPGPAFPQQVPLVQQGSRELQDSFHLRPSPYSN 540
           SDFQLLPAQGSSLTNFFPDVGFDQQSMRPGPAFPQQVPLVQQGSRELQDSFHLRPSPYSN
Sbjct: 481 SDFQLLPAQGSSLTNFFPDVGFDQQSMRPGPAFPQQVPLVQQGSRELQDSFHLRPSPYSN 540

Query: 541 CGSLPNTILP-DSSTSLFKDLNSALAGLPEVSLNVDTPFPLEEELQIEPLSLDGLNMLSD 599
           CGSLPNTILP DSSTSLFKDLNSALAGLPEVSLNVDTPFPLEEELQIEPLSLDGLNMLSD
Sbjct: 541 CGSLPNTILPEDSSTSLFKDLNSALAGLPEVSLNVDTPFPLEEELQIEPLSLDGLNMLSD 600

Query: 600 SSMGLLDPSVEETFRADRL 618
           SSMGLLDPSVEETFRADRL
Sbjct: 601 SSMGLLDPSVEETFRADRL 619


>gi|32171215 CREB regulated transcription coactivator 2 [Homo
           sapiens]
          Length = 693

 Score =  337 bits (863), Expect = 3e-92
 Identities = 271/710 (38%), Positives = 353/710 (49%), Gaps = 116/710 (16%)

Query: 2   AASPGSGSA---NPRKFSEKIALHTQRQAEETRAFEQLMTDLTLSRVQFQKLQ-QLRLTQ 57
           A  PGS +A   NPRKFSEKIAL  QRQAEET AFE++M D+  +R+Q QKL+     + 
Sbjct: 6   ANGPGSATASASNPRKFSEKIALQKQRQAEETAAFEEVMMDIGSTRLQAQKLRLAYTRSS 65

Query: 58  YHGGSLPNVSQLRSSASEFQPSFHQA-DNVRGTRHHGLVERPSRN---RFHPLHRRSGDK 113
           ++GGSLPNV+Q+ S  +EFQ   H   D+ R TRHHGLVER  R+      PL R +   
Sbjct: 66  HYGGSLPNVNQIGSGLAEFQSPLHSPLDSSRSTRHHGLVERVQRDPRRMVSPLRRYT--- 122

Query: 114 PGRQFDGSAFGANYSSQPLDESWPRQQPPWKD---EKHPGFRLTSALNRTNSDSALHTSA 170
             R  D S +   Y S P + SW R+   W +   EK   FRL SALNRT+SDSALHTS 
Sbjct: 123 --RHIDSSPYSPAYLSPPPESSW-RRTMAWGNFPAEKGQLFRLPSALNRTSSDSALHTSV 179

Query: 171 LSTKPQDPYGGGGQ-SAWPAPYMGFCDGENNGHGEVASFPGPLKEENLLNVPKPLPKQLW 229
           ++  PQD Y G    S  P+   G  DGE +          P  EENLL+  K L K  W
Sbjct: 180 MNPSPQDTYPGPTPPSILPSRRGGILDGEMDPKV-------PAIEENLLD-DKHLLKP-W 230

Query: 230 ETKEIQSLSGRPRSCDVGGGNAFPHNGQNLGLSPFLGTLNTGGSLPDLTNLHYSTPLPAS 289
           + K++ S S RPRSC+V G N FP   Q   +      +NTGGSLPDLTNLH+  PLP  
Sbjct: 231 DAKKLSSSSSRPRSCEVPGINIFPSPDQPANVPVLPPAMNTGGSLPDLTNLHFPPPLPTP 290

Query: 290 LDTTDHHFGSMSVGNSVNNIPAAMTHLGIR---------SSSGLQSSRSNPSIQATLNKT 340
           LD  +  + S+S GNS +N+   MTHLGI           + GL S  S+PS+Q++L+  
Sbjct: 291 LDPEETAYPSLSGGNSTSNLTHTMTHLGISRGMGLGPGYDAPGLHSPLSHPSLQSSLSNP 350

Query: 341 VLSSSLN--------NHPQTSVPNASALHPSLRLFSLSNPSLSTTNLSGPS--------- 383
            L +SL+        +H   S+P +S     L   SL +PSLS   LS  S         
Sbjct: 351 NLQASLSSPQPQLQGSHSHPSLPASSLARHVLPTTSLGHPSLSAPALSSSSSSSSTSSPV 410

Query: 384 ---------------RRRQPPVSPLTLSPGP----EAHQGFSRQLSSTSPLAPYPTSQMV 424
                            R+ P+SPL+L  GP     + Q   +Q S T        +Q V
Sbjct: 411 LGAPSYPASTPGASPHHRRVPLSPLSLLAGPADARRSQQQLPKQFSPTMSPTLSSITQGV 470

Query: 425 SSDRSQLSFLPTEAQAQVSPPPPYPAP------QELTQPLLQQPRAPE------------ 466
             D S+LS        Q  PP PY +P      Q  T   LQQP  P             
Sbjct: 471 PLDTSKLS------TDQRLPPYPYSSPSLVLPTQPHTPKSLQQPGLPSQSCSVQSSGGQP 524

Query: 467 -------------APAQQPQAASSLPQSDFQLLPAQGSSLTNFFPDVGFDQQSMRPGPAF 513
                         P+   Q +   P SDF L   +  S+ +    +  D      GP F
Sbjct: 525 PGRQSHYGTPYPPGPSGHGQQSYHRPMSDFNLGNLEQFSMESPSASLVLDPPGFSEGPGF 584

Query: 514 -PQQVPLVQQGSRELQDSFHLRPSPYSNCGSLPNTILP-DSSTSLFKDLNSALAGLP--E 569
              + P+   G ++     H   +  S  GS PN IL  DSS    K++ +ALAG+P  E
Sbjct: 585 LGGEGPM--GGPQDPHTFNHQNLTHCSRHGSGPNIILTGDSSPGFSKEIAAALAGVPGFE 642

Query: 570 VS-LNVDTPFPLEEELQIEPLSLDGLNMLSDSSMGLLDPSVEETFRADRL 618
           VS   ++    LE+EL++EPL L+GLNMLSD    L DP+VEE+FR+DRL
Sbjct: 643 VSAAGLELGLGLEDELRMEPLGLEGLNMLSDPCALLPDPAVEESFRSDRL 692


>gi|148596965 mucoepidermoid carcinoma translocated 1 isoform 1
           [Homo sapiens]
          Length = 634

 Score =  283 bits (724), Expect = 3e-76
 Identities = 239/681 (35%), Positives = 318/681 (46%), Gaps = 121/681 (17%)

Query: 9   SANPRKFSEKIALHTQRQAEETRAFEQLMTDLTLSR---VQFQKLQQLRLT----QYHGG 61
           S NPRKFSEKIALH Q+QAEET AFE++M DL+L+R   +Q QK Q L+L     QY+GG
Sbjct: 4   SNNPRKFSEKIALHNQKQAEETAAFEEVMKDLSLTRAARLQLQKSQYLQLGPSRGQYYGG 63

Query: 62  SLPNVSQLRSSASE--FQPSFHQA--DNVRGTRHHGLVERP--SRNRFHPLHRR--SGDK 113
           SLPNV+Q+ S   +  FQ  F  +  D  R TRHHGLV+R    R R    HRR  S DK
Sbjct: 64  SLPNVNQIGSGTMDLPFQTPFQSSGLDTSRTTRHHGLVDRVYRERGRLGSPHRRPLSVDK 123

Query: 114 PGRQFDGSAFGANYSSQPLDESWPRQQPPWKDEKHPGFRLTSALNRTNSDSALHTSALST 173
            GRQ D   +G  Y S P D SW                      RTNSDSALH S ++ 
Sbjct: 124 HGRQADSCPYGTMYLSPPADTSW---------------------RRTNSDSALHQSTMTP 162

Query: 174 KPQDPYGGGGQSAWPAPYMGFCDGENNGHGEVASFPGPLKEENLLNVPKPLPKQLWETKE 233
              + +  G Q       +            + + PG   EE      K L KQ W+TK+
Sbjct: 163 TQPESFSSGSQDVHQKRVL------------LLTVPG--MEETTSEADKNLSKQAWDTKK 208

Query: 234 IQSLSGRPRSCDVGGGNAFPHNGQNLGLSPFLGTLNTGGSLPDLTNLHYSTPLPASLDTT 293
             S   RP+SC+V G N FP   Q    +    T NTGGSLPDLTN+H+ +PLP  LD  
Sbjct: 209 TGS---RPKSCEVPGINIFPSADQENTTALIPATHNTGGSLPDLTNIHFPSPLPTPLDPE 265

Query: 294 DHHFGSMSVGNSVNNIPAAMTHLGI-RSSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQT 352
           +  F ++S  +S  N+ A +THLGI  +  G+ +  S+P        + LS S     Q 
Sbjct: 266 EPTFPALSSSSSTGNLAANLTHLGIGGAGQGMSTPGSSPQ-HRPAGVSPLSLSTEARRQQ 324

Query: 353 SVPNASALHPSLRLFSLSNPSLSTT---NLSGPSRRRQPPVSPLTLSPGPEAHQGFSRQL 409
           + P  S L P  +  ++   SL           +  +QPP  P    P P A        
Sbjct: 325 ASPTLSPLSPITQAVAMDALSLEQQLPYAFFTQAGSQQPPPQPQPPPPPPPA-------- 376

Query: 410 SSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPPPP--YPAPQELTQPLLQQPRAP-- 465
           S   P  P P + +       L  LP+ +  +   PPP     P  L Q   + P  P  
Sbjct: 377 SQQPPPPPPPQAPVRLPPGGPL--LPSASLTRGPQPPPLAVTVPSSLPQSPPENPGQPSM 434

Query: 466 -----EAPAQQ---PQAASSLPQSDFQLLPAQG----------SSLTNFFPDVGFDQQ-S 506
                 APA Q     A S   QS    +  QG          S+L + F D  ++QQ +
Sbjct: 435 GIDIASAPALQQYRTSAGSPANQSPTSPVSNQGFSPGSSPQHTSTLGSVFGDAYYEQQMA 494

Query: 507 MRPGPAFPQQV-------------PLVQQGSR----------------ELQDSFHLRPSP 537
            R   A   Q+              L   GS                  L DS  L  + 
Sbjct: 495 ARQANALSHQLEQFNMMENAISSSSLYSPGSTLNYSQAAMMGLTGSHGSLPDSQQLGYAS 554

Query: 538 YSNCGSLPNTILPDSSTSLFKDLNSALAGLPEVSLNVDTPFPLEEELQIEPLSLDGLNML 597
           +S   ++  T+  +S  SL K+L S+LAG+ +VS + D+ FPL +EL+I+PL+LDGL+ML
Sbjct: 555 HSGIPNIILTVTGESPPSLSKELTSSLAGVGDVSFDSDSQFPL-DELKIDPLTLDGLHML 613

Query: 598 SDSSMGLLDPSVEETFRADRL 618
           +D  M L DP+ E+TFR DRL
Sbjct: 614 NDPDMVLADPATEDTFRMDRL 634


>gi|148596988 mucoepidermoid carcinoma translocated 1 isoform 3
           [Homo sapiens]
          Length = 650

 Score =  278 bits (710), Expect = 1e-74
 Identities = 241/697 (34%), Positives = 320/697 (45%), Gaps = 137/697 (19%)

Query: 9   SANPRKFSEKIALHTQRQAEETRAFEQLMTDLTLSR---VQFQKLQQLRLT----QYHGG 61
           S NPRKFSEKIALH Q+QAEET AFE++M DL+L+R   +Q QK Q L+L     QY+GG
Sbjct: 4   SNNPRKFSEKIALHNQKQAEETAAFEEVMKDLSLTRAARLQLQKSQYLQLGPSRGQYYGG 63

Query: 62  SLPNVSQLRSSASE--FQPS----------------FHQA--DNVRGTRHHGLVERP--S 99
           SLPNV+Q+ S   +  FQPS                F  +  D  R TRHHGLV+R    
Sbjct: 64  SLPNVNQIGSGTMDLPFQPSGFLGEALAAAPVSLTPFQSSGLDTSRTTRHHGLVDRVYRE 123

Query: 100 RNRFHPLHRR--SGDKPGRQFDGSAFGANYSSQPLDESWPRQQPPWKDEKHPGFRLTSAL 157
           R R    HRR  S DK GRQ D   +G  Y S P D SW                     
Sbjct: 124 RGRLGSPHRRPLSVDKHGRQADSCPYGTMYLSPPADTSW--------------------- 162

Query: 158 NRTNSDSALHTSALSTKPQDPYGGGGQSAWPAPYMGFCDGENNGHGEVASFPGPLKEENL 217
            RTNSDSALH S ++    + +  G Q       +            + + PG   EE  
Sbjct: 163 RRTNSDSALHQSTMTPTQPESFSSGSQDVHQKRVL------------LLTVPG--MEETT 208

Query: 218 LNVPKPLPKQLWETKEIQSLSGRPRSCDVGGGNAFPHNGQNLGLSPFLGTLNTGGSLPDL 277
               K L KQ W+TK+  S   RP+SC+V G N FP   Q    +    T NTGGSLPDL
Sbjct: 209 SEADKNLSKQAWDTKKTGS---RPKSCEVPGINIFPSADQENTTALIPATHNTGGSLPDL 265

Query: 278 TNLHYSTPLPASLDTTDHHFGSMSVGNSVNNIPAAMTHLGI-RSSSGLQSSRSNPSIQAT 336
           TN+H+ +PLP  LD  +  F ++S  +S  N+ A +THLGI  +  G+ +  S+P     
Sbjct: 266 TNIHFPSPLPTPLDPEEPTFPALSSSSSTGNLAANLTHLGIGGAGQGMSTPGSSPQ-HRP 324

Query: 337 LNKTVLSSSLNNHPQTSVPNASALHPSLRLFSLSNPSLSTT---NLSGPSRRRQPPVSPL 393
              + LS S     Q + P  S L P  +  ++   SL           +  +QPP  P 
Sbjct: 325 AGVSPLSLSTEARRQQASPTLSPLSPITQAVAMDALSLEQQLPYAFFTQAGSQQPPPQPQ 384

Query: 394 TLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPPPP--YPAP 451
              P P A        S   P  P P + +       L  LP+ +  +   PPP     P
Sbjct: 385 PPPPPPPA--------SQQPPPPPPPQAPVRLPPGGPL--LPSASLTRGPQPPPLAVTVP 434

Query: 452 QELTQPLLQQPRAP-------EAPAQQ---PQAASSLPQSDFQLLPAQG----------S 491
             L Q   + P  P        APA Q     A S   QS    +  QG          S
Sbjct: 435 SSLPQSPPENPGQPSMGIDIASAPALQQYRTSAGSPANQSPTSPVSNQGFSPGSSPQHTS 494

Query: 492 SLTNFFPDVGFDQQ-SMRPGPAFPQQV-------------PLVQQGSR------------ 525
           +L + F D  ++QQ + R   A   Q+              L   GS             
Sbjct: 495 TLGSVFGDAYYEQQMAARQANALSHQLEQFNMMENAISSSSLYSPGSTLNYSQAAMMGLT 554

Query: 526 ----ELQDSFHLRPSPYSNCGSLPNTILPDSSTSLFKDLNSALAGLPEVSLNVDTPFPLE 581
                L DS  L  + +S   ++  T+  +S  SL K+L S+LAG+ +VS + D+ FPL 
Sbjct: 555 GSHGSLPDSQQLGYASHSGIPNIILTVTGESPPSLSKELTSSLAGVGDVSFDSDSQFPL- 613

Query: 582 EELQIEPLSLDGLNMLSDSSMGLLDPSVEETFRADRL 618
           +EL+I+PL+LDGL+ML+D  M L DP+ E+TFR DRL
Sbjct: 614 DELKIDPLTLDGLHMLNDPDMVLADPATEDTFRMDRL 650


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 53.1 bits (126), Expect = 7e-07
 Identities = 50/176 (28%), Positives = 74/176 (42%), Gaps = 13/176 (7%)

Query: 329 SNPSIQATLNKTV--LSSSLNNHPQTSVPNASALHPSLRLFSLSNPSLSTTNLSGPSRRR 386
           ++P +Q +L+  V  LSS L  HP  ++ + ++  P   L SL  P L T +   P   +
Sbjct: 465 ASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQ 524

Query: 387 QPPVSPLTLSP-------GPEAHQGFSRQLSSTS-PLAPYPTSQMVSSDRSQLSFLPTEA 438
            PP S LT  P        P   Q  S  L++      P P    + +  S L+  P E 
Sbjct: 525 TPPAS-LTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPET 583

Query: 439 QAQVSPPPPYPAPQELTQPLLQQPRAPEAP--AQQPQAASSLPQSDFQLLPAQGSS 492
            + ++ PPP   P   + PL   P  P +P     PQA   L     Q  P+  +S
Sbjct: 584 PSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPAS 639



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 86/311 (27%), Positives = 116/311 (37%), Gaps = 65/311 (20%)

Query: 303 GNSVNNIPAAMTHLGIRSSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASALHP 362
           G S    P A  H       GLQ+ R                     PQ + P   A  P
Sbjct: 256 GPSARGTPRAPAHPSQPKPKGLQALRP--------------------PQVTPPRKDAA-P 294

Query: 363 SLRLFSLSNPSLSTTNLSGPSRRRQPPVS------PLTLSPGPEAHQGFSRQLSSTSPLA 416
           +L    LS+  L+T + SG   R  PP        P TL P P         L+  SP A
Sbjct: 295 ALG--PLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLP--LAPPSPSA 350

Query: 417 PYPTSQMVSSDRS--------QLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPEAP 468
           P P+ Q + S  +         ++  P +A   +   PP   P  LT P LQ P +P A 
Sbjct: 351 P-PSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLA- 408

Query: 469 AQQPQAASSLPQSDFQ-------LLPAQ-GSSLTNFFPDVGFDQQSMRPGPAFPQQVPLV 520
               QA +SL     Q       + P Q  +SLT+        + +  P  + P Q PL 
Sbjct: 409 LSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTS------PSRPASTPPDSPPLQAPLS 462

Query: 521 QQGSRELQDSFHLRPSPYSNCGSLPNTILPDSSTSLFKDLNSALAGLPEVSLNVDTPFPL 580
              S  LQ S     SP S+    P TI P       + L+S  +  P+  L+     PL
Sbjct: 463 LPASPPLQTSLSPAVSPLSS----PLTIHP------LQALSSLASHSPQAPLSSLIMPPL 512

Query: 581 EEELQIEPLSL 591
           E +  + P SL
Sbjct: 513 ETQSSLAPPSL 523



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 71/270 (26%), Positives = 100/270 (37%), Gaps = 39/270 (14%)

Query: 263 PFLGTLNTGGSLPDLTNLHYSTPLPASLDTTDHHFGSMSVGNSVNNIPAAMTHLGIRSSS 322
           P    L+   S P  T+L  +   P S   T H   ++S  +  ++ P A     I    
Sbjct: 456 PLQAPLSLPASPPLQTSLSPAVS-PLSSPLTIHPLQALS--SLASHSPQAPLSSLIMPPL 512

Query: 323 GLQSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASALHPSLRLFS--LSNPSLSTTNLS 380
             QSS + PS+Q         +SL   P  ++P+ +   P L+  S  L+ P L T    
Sbjct: 513 ETQSSLAPPSLQTP------PASLTTPPLENLPSLAP--PPLQTASAPLTTPHLETPPCP 564

Query: 381 GPSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQA 440
            P   + PP SPLT +P PE     +       P    P           L  LP+   +
Sbjct: 565 APCPLQAPP-SPLT-TPPPETPSSIATPPPQAPPALASPP----------LQGLPSPPLS 612

Query: 441 QVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQSDFQLLPAQGSSLTNFFPDV 500
            ++ PPP  AP  L  P LQ P +P A       A+  PQ+   L              V
Sbjct: 613 PLATPPP-QAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALA-------------V 658

Query: 501 GFDQQSMRPGPAFPQQVPLVQQGSRELQDS 530
              Q    P P+ P Q P     S  +  S
Sbjct: 659 HLLQAPFSPPPSPPVQAPFSPPASPPVSPS 688



 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 36/100 (36%), Positives = 46/100 (46%), Gaps = 13/100 (13%)

Query: 382 PSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQ 441
           PS    PP+SPL  +P P+A    +  L   +P +P P+  +      Q  F P  A   
Sbjct: 634 PSPPASPPLSPLA-TPSPQAPNALAVHLLQ-APFSPPPSPPV------QAPFSPP-ASPP 684

Query: 442 VSPP--PPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLP 479
           VSP   PP  AP  L  P LQ P  P  PA  P + S+ P
Sbjct: 685 VSPSATPPSQAPPSLAAPPLQVP--PSPPASPPMSPSATP 722



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 59/225 (26%), Positives = 74/225 (32%), Gaps = 23/225 (10%)

Query: 350 PQTSVPNASALHPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSPG--PEAHQGFSR 407
           P    PNA A+H     FS           S P+    PPVSP    P   P +      
Sbjct: 648 PSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA---SPPVSPSATPPSQAPPSLAAPPL 704

Query: 408 QLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPP----------PPYPAPQELTQP 457
           Q+  + P +P  +       ++         Q   SPP          PP   P  L  P
Sbjct: 705 QVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAP 764

Query: 458 LLQQPRAPEAPAQQ-------PQAASSLPQSDFQLLPAQGSSLTNFFPDVGFDQQSMRPG 510
            LQ P +P A           PQA  +L     Q LP+  +S     P        M P 
Sbjct: 765 PLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL 824

Query: 511 PAFPQQVPLVQQGSRELQDSFHLRPSPYSNCGSLPNTILPDSSTS 555
              P Q P V   +  LQ       SP       P T  PD+S S
Sbjct: 825 ATPPPQAPPV-LAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVS 868



 Score = 36.6 bits (83), Expect = 0.070
 Identities = 82/322 (25%), Positives = 118/322 (36%), Gaps = 49/322 (15%)

Query: 311 AAMTHLGIRSSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSV-----PNASA--LHPS 363
           AA T +G+   +   S+R  P  +    K+V S+S ++  + S      P+A      P+
Sbjct: 182 AAGTEVGLPRPA--PSARPRPPTEGP-RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPA 238

Query: 364 LRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSP-------LA 416
            R  S S   LS+   SGPS R  P        P P+  Q   R    T P       L 
Sbjct: 239 SRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQAL-RPPQVTPPRKDAAPALG 297

Query: 417 PYPTSQMVSSDRSQLSFLPTEAQAQVSPPP-----PYPAPQELTQPLLQQ-PRAPEAPAQ 470
           P  +S + +         P+  +A+  PPP     P PA    + PL    P AP +P+ 
Sbjct: 298 PLSSSPLATPS-------PSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSA 350

Query: 471 QPQAASSLPQSDFQLLPAQGSSLTNFFPDVGFDQQSMRPGPAFPQQVPLVQQGSRELQDS 530
            P           Q LP+  ++  +  P        M+  P+  Q +P +Q        S
Sbjct: 351 PP---------SLQTLPSPPATPPSQAPP-SMTTPPMQAPPSL-QTIPPIQVPHSLTSPS 399

Query: 531 FHLRPSPYSNCG-----SLPNTILPDSSTSLFKDLNSALAGLPEVSLNVDTPFPLEEELQ 585
               PSP +        SL +  L  + + L        A L   S    TP P    LQ
Sbjct: 400 LQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTP-PDSPPLQ 458

Query: 586 IEPLSLDGLNMLSDSSMGLLDP 607
             PLSL     L  S    + P
Sbjct: 459 -APLSLPASPPLQTSLSPAVSP 479



 Score = 34.3 bits (77), Expect = 0.35
 Identities = 32/112 (28%), Positives = 41/112 (36%), Gaps = 9/112 (8%)

Query: 382 PSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPY------PTSQMVSSDRSQLSFLP 435
           PS     P+SPL   P P+A    +       P  P       P S   S   S L+  P
Sbjct: 770 PSPPASLPMSPLA-KPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP 828

Query: 436 TEAQAQVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQSDFQLLP 487
            +A   ++ P     P     P LQ PR P  P   P  + S P+    L P
Sbjct: 829 PQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPG--PDTSVSGPRLTLALAP 878


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 63/215 (29%), Positives = 83/215 (38%), Gaps = 41/215 (19%)

Query: 303 GNSVNNIPAAMTHLGIRSSSGLQSSR----SNPSIQATLNKTVLSSSLNNHPQTSVPNAS 358
           G S    P A  H       GLQ+ R    + P   A      LSSS    P  S P + 
Sbjct: 247 GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSP 306

Query: 359 ALHPSLRLFS---LSNPSLSTTNLSGPSRRR------QPPVSPLTLSPGPEAHQGFSRQ- 408
           +  PSL+       + PS +TT+L  P+ +        PP+SPL  +P P+A    +   
Sbjct: 307 SAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLA-TPPPQAPPALALPP 365

Query: 409 -LSSTSPLAPYPTSQMVSSDRS----------QLSFLPTEA---QAQVSPP--------- 445
             +  SP A  P S + +              Q  F P  +   QA  SPP         
Sbjct: 366 LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSA 425

Query: 446 -PPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLP 479
            PP  AP  L  P LQ P  P  PA  P + S+ P
Sbjct: 426 TPPSQAPPSLAAPPLQVP--PSPPASPPMSPSATP 458



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 60/222 (27%), Positives = 82/222 (36%), Gaps = 29/222 (13%)

Query: 320 SSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASALHPSLRLFSLSNPSLSTTNL 379
           +  GLQ   S      + + T LSS   + P       +  HPS +       +L    +
Sbjct: 221 AGGGLQRPASR---SLSSSATPLSSPARSGPSARGTPRAPAHPS-QPKPKGLQALRPPQV 276

Query: 380 SGPSRRRQPPVSPLTLSP----GPEAHQGFSRQLS-STSPLAPY-PTSQMVSSDRSQL-- 431
           + P +   P + PL+ SP     P A    S   S  T P  P  P SQ  +S  S    
Sbjct: 277 TPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQ 336

Query: 432 ---SFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQSDFQLLPA 488
              SFLP+   + ++ PPP  AP  L  P LQ P +P A       A+  PQ+   L   
Sbjct: 337 ATHSFLPSPPLSPLATPPP-QAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALA-- 393

Query: 489 QGSSLTNFFPDVGFDQQSMRPGPAFPQQVPLVQQGSRELQDS 530
                      V   Q    P P+ P Q P     S  +  S
Sbjct: 394 -----------VHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 424


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
           sapiens]
          Length = 5537

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 74/292 (25%), Positives = 107/292 (36%), Gaps = 36/292 (12%)

Query: 321 SSGLQSSRSNPSIQATLNKTVLSSSLNNHPQ----TSVPNASALHPSLRLFSLSNPSLST 376
           S  L++  S P   + L+     S L+  P+    +  P AS L P      +S P   +
Sbjct: 529 SPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEES 588

Query: 377 TNLSGPSRRRQ-PPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLP 435
                P   R  PP     LSP PE            SPL+P P +  +S         P
Sbjct: 589 PMSPPPEASRLFPPFEESPLSPPPEE-----------SPLSPPPEASRLSPPPEDSPMSP 637

Query: 436 TEAQAQVSPPP------PYPAPQELTQPLLQQPRAP---EAPAQQPQAASSL--PQSDFQ 484
              ++ +SPPP      P P    L+ P  + P +P   E+P   P  AS L  P  D  
Sbjct: 638 PPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSP 697

Query: 485 LLPAQGSSLTNFFPD-----VGFDQQSMRPGPAFPQQVPLVQQGSRELQ-DSFHLRPSPY 538
             P    S  +  P+     +  ++  + P P  PQ  P  +      + +  HL P P 
Sbjct: 698 TSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPE 757

Query: 539 SNCGSLPNTILPDSSTSLFKDLNSALAGLPEVSLNVDTPF--PLEEELQIEP 588
               S P    P  S    +    A+   P +S   + P   P  EEL + P
Sbjct: 758 EPHLS-PQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSP 808



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 79/281 (28%), Positives = 108/281 (38%), Gaps = 56/281 (19%)

Query: 331 PSIQATLNKTVLSSSLNNHPQTSVPNASALHPSLRLFSLSNPSLSTTNLSGPSRRRQPPV 390
           P ++A LN+ +        P    P  S L P         P  S T+    + R  PP 
Sbjct: 428 PQLEAPLNEEM--------PLLPPPEESPLSPP--------PEESPTSPPPEASRLSPPP 471

Query: 391 SPLTLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPP---PP 447
             L  SP PEA    SR L   SPL+P P    +S       F P E ++ +SPP   PP
Sbjct: 472 EELPASPLPEALH-LSRPLEE-SPLSPPPEESPLSPPPESSPFSPLE-ESPLSPPEESPP 528

Query: 448 YPA-------PQE---LTQPLLQQPRAP---EAPAQQPQAASSL--PQSDFQLLPAQGSS 492
            PA       P E   L+ P  + P +P   E P   P  AS L  P  +  + P    S
Sbjct: 529 SPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEES 588

Query: 493 LTNFFPDVG-----FDQQSMRPGPAFPQQVPLVQQGSRELQDSFHLRPSPYSNCGSLPNT 547
             +  P+       F++  + P    P++ PL         ++  L P P  +  S P  
Sbjct: 589 PMSPPPEASRLFPPFEESPLSPP---PEESPLSPP-----PEASRLSPPPEDSPMSPP-- 638

Query: 548 ILPDSSTSLFKDLNSALAGLPEVSLNVDTPFPLEEELQIEP 588
             P+ S        S L+ LP VS    +P P E  L   P
Sbjct: 639 --PEESPMSPPPEVSRLSPLPVVSRL--SPPPEESPLSPPP 675



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 42/165 (25%), Positives = 63/165 (38%), Gaps = 13/165 (7%)

Query: 325 QSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASALHPSLRLFSLSNPSLSTTNLSGPSR 384
           +S  S P  ++ L+    SS  +   ++ +       PS  L +  +P    + LS P  
Sbjct: 491 ESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFE 550

Query: 385 RR--QPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQV 442
                PP   L  SP PEA +         SP++P P    +S         P   ++ +
Sbjct: 551 ESPLSPPPEELPTSPPPEASR--LSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPL 608

Query: 443 SPPP------PYPAPQELTQPLLQQPRAP---EAPAQQPQAASSL 478
           SPPP      P P    L+ P    P +P   E+P   P   S L
Sbjct: 609 SPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRL 653



 Score = 35.4 bits (80), Expect = 0.16
 Identities = 61/246 (24%), Positives = 94/246 (38%), Gaps = 28/246 (11%)

Query: 338  NKTVLSSSLNNHPQTSVPNASALHPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSP 397
            ++T+LS       Q ++       P L+ FS       T  L+G  +    P      + 
Sbjct: 3981 SRTLLSPQQQQQQQVALGPGMPAKP-LQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATE 4039

Query: 398  GPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLS-FLPTEAQAQVSPPPPYPAPQELTQ 456
            GP  HQG         PLA   T + ++++  ++   L  ++Q  +  P P P P  L  
Sbjct: 4040 GPSTHQG--------GPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQ- 4090

Query: 457  PLLQQPRAPEAPAQQPQAASSLPQ----SDFQL---LPAQGSSLTNFF--PDVGFDQQ-- 505
              LQ P     P QQ Q  S L      S  QL     ++ SS+ +    P V    Q  
Sbjct: 4091 --LQPPL--RLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPG 4146

Query: 506  SMRPGPAFPQQVPLVQQGSRELQDSFHLRPSPYSNCG-SLPNTILPDSSTSLFKDLNSAL 564
            SM      PQQ P++++  +        +P P    G  LP   +  +   L   L   L
Sbjct: 4147 SMTQNLLGPQQ-PMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVL 4205

Query: 565  AGLPEV 570
            A  P++
Sbjct: 4206 AKNPQL 4211



 Score = 33.5 bits (75), Expect = 0.60
 Identities = 43/167 (25%), Positives = 61/167 (36%), Gaps = 33/167 (19%)

Query: 387 QPPVSPLT----LSPGPEA-HQGFSRQLSSTSP------LAPYPTSQMVSSDRSQLSFLP 435
           +P +SP      LSP PE  H     +    SP      L+P P    +S    +    P
Sbjct: 785 EPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSP 844

Query: 436 TEAQAQVSP----PPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQSDFQLLPAQGS 491
              ++ +SP    PP  P P+          + PE P Q P A   LP     L P  G 
Sbjct: 845 RPEESHLSPELEKPPLSPRPE----------KPPEEPGQCP-APEELP-----LFPPPGE 888

Query: 492 -SLTNFFPDVGFDQQSMRPGPAFPQQVPLVQQGSRELQDSFHLRPSP 537
            SL+    +    +    P    P+++PL   G   L     + P P
Sbjct: 889 PSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQL-MPPDP 934



 Score = 32.0 bits (71), Expect = 1.7
 Identities = 30/84 (35%), Positives = 39/84 (46%), Gaps = 15/84 (17%)

Query: 409  LSSTSPLAPYPTSQ------MVSSDRSQLSFLPTEAQAQVSPPPPYPAPQEL---TQPLL 459
            L   SP AP P +Q      + + D  QLS  P E   + SPPP   AP      T+PL+
Sbjct: 4879 LKQESP-APEPPTQHSYTYNVSNLDVRQLSAPPPE---EPSPPPSPLAPSPASPPTEPLV 4934

Query: 460  QQPRAP--EAPAQQPQAASSLPQS 481
            + P  P  E P   P   +S P+S
Sbjct: 4935 ELPTEPLAEPPVPSPLPLASSPES 4958



 Score = 31.6 bits (70), Expect = 2.3
 Identities = 47/175 (26%), Positives = 64/175 (36%), Gaps = 35/175 (20%)

Query: 389  PVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQ-AQVSPPP- 446
            PV P+ L P P +  G        SP+   P     S    Q S +P  +  +Q SPP  
Sbjct: 995  PVPPMILPPSPGSPVG------PASPILMEPLPPQCSP-LLQHSLVPQNSPPSQCSPPAL 1047

Query: 447  --PYPAP-------------QELTQPLLQQPRAPEAPAQQPQAASSLPQSDFQL---LPA 488
                P+P              EL +   ++   PE PA +P A S LP     L    P+
Sbjct: 1048 PLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPS 1107

Query: 489  QGSSLTNF-------FPDVGFDQQSMRPGPA-FPQQVPLVQQGSRELQDSFHLRP 535
               +L +F        P  G D    +P P   P  +    +GS  L D   L P
Sbjct: 1108 PAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASELKGSPVLLDPEELAP 1162



 Score = 31.2 bits (69), Expect = 3.0
 Identities = 32/96 (33%), Positives = 39/96 (40%), Gaps = 19/96 (19%)

Query: 380  SGPSRRRQP--PVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQL----SF 433
            +GP  +  P  P  P  LS GP         L    P  P P+S       SQL    S 
Sbjct: 4279 AGPRPQGPPRLPAPPGALSTGPV--------LGPVHPTPP-PSSPQEPKRPSQLPSPSSQ 4329

Query: 434  LPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPEAPA 469
            LPTEAQ     PP +P   +   P L+ P    +PA
Sbjct: 4330 LPTEAQL----PPTHPGTPKPQGPTLEPPPGRVSPA 4361



 Score = 30.0 bits (66), Expect = 6.6
 Identities = 35/129 (27%), Positives = 47/129 (36%), Gaps = 18/129 (13%)

Query: 381  GPSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLA----------PYPTSQMVSSDRSQ 430
            G   R Q P     L+P P +H    R  S T P A          P P S      RS 
Sbjct: 2344 GLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRS- 2402

Query: 431  LSFLPTEAQAQVSPPPPYPAPQELTQ-PLLQQPRAPEAPAQQPQAASSLPQSDFQLLPAQ 489
               LP++  ++V   P  P  Q  +Q PL  +P + EA    P          +   P++
Sbjct: 2403 ---LPSDPFSRV---PASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSR 2456

Query: 490  GSSLTNFFP 498
              S   F P
Sbjct: 2457 PQSRDPFAP 2465


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 58/204 (28%), Positives = 85/204 (41%), Gaps = 38/204 (18%)

Query: 310 PAAMTHLGIRSSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASALHPSLRLFS- 368
           P + + L   S S    S++ P++ AT + + L+  L      + P+ SA  PSL+    
Sbjct: 298 PLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSA-PPSLQTLPS 356

Query: 369 --LSNPSLSTTNLSGPSRRR------QPPVSPLTLSPGPEAHQGFSRQ--LSSTSPLAPY 418
              + PS +TT+L  P+ +        PP+SPL  +P P+A    +     +  SP A  
Sbjct: 357 PPATPPSQATTSLGSPTLQATHSFLPSPPLSPLA-TPPPQAPPALALPPLQAPPSPPASP 415

Query: 419 PTSQMVSSDRS----------QLSFLPTEA---QAQVSPP----------PPYPAPQELT 455
           P S + +              Q  F P  +   QA  SPP          PP  AP  L 
Sbjct: 416 PLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLA 475

Query: 456 QPLLQQPRAPEAPAQQPQAASSLP 479
            P LQ P  P  PA  P + S+ P
Sbjct: 476 APPLQVP--PSPPASPPMSPSATP 497



 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 63/230 (27%), Positives = 86/230 (37%), Gaps = 24/230 (10%)

Query: 303 GNSVNNIPAAMTHLGIRSSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASALHP 362
           G S    P A  H       GLQ+ R     Q T  +   + +L   P +S P A+   P
Sbjct: 256 GPSARGTPRAPAHPSQPKPKGLQALRPP---QVTPPRKDAAPALG--PLSSSPLATP-SP 309

Query: 363 SLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPTSQ 422
           S  L S + P+L  T  S  S       +PL L+P   +     + L S     P   + 
Sbjct: 310 SAALQSQAPPTLPATPHS--SSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATT 367

Query: 423 MVSSDRSQL--SFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQ 480
            + S   Q   SFLP+   + ++ PPP  AP  L  P LQ P +P A       A+  PQ
Sbjct: 368 SLGSPTLQATHSFLPSPPLSPLATPPP-QAPPALALPPLQAPPSPPASPPLSPLATPSPQ 426

Query: 481 SDFQLLPAQGSSLTNFFPDVGFDQQSMRPGPAFPQQVPLVQQGSRELQDS 530
           +   L              V   Q    P P+ P Q P     S  +  S
Sbjct: 427 APNALA-------------VHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 463



 Score = 35.4 bits (80), Expect = 0.16
 Identities = 56/199 (28%), Positives = 80/199 (40%), Gaps = 30/199 (15%)

Query: 311 AAMTHLGIRSSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSV-----PNASA--LHPS 363
           AA T +G+   +   S+R  P  +    K+V S+S ++  + S      P+A      P+
Sbjct: 182 AAGTEVGLPRPA--PSARPRPPTEGP-RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPA 238

Query: 364 LRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSPGPEAHQGF-SRQLS------------ 410
            R  S S   LS+   SGPS R  P        P P+  Q     Q++            
Sbjct: 239 SRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP 298

Query: 411 -STSPLA-PYPTSQMVSSDRSQLSFLP--TEAQAQVSPPPPYPAPQELTQPLLQQPRAPE 466
            S+SPLA P P++ + S     L   P  +    Q++ P P   P     P LQ    P 
Sbjct: 299 LSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQ--TLPS 356

Query: 467 APAQQP-QAASSLPQSDFQ 484
            PA  P QA +SL     Q
Sbjct: 357 PPATPPSQATTSLGSPTLQ 375


>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
            sapiens]
          Length = 1362

 Score = 49.7 bits (117), Expect = 8e-06
 Identities = 70/216 (32%), Positives = 79/216 (36%), Gaps = 33/216 (15%)

Query: 346  LNNHPQTSVPNASALHPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLT----LSPGPEA 401
            LN H   S P   ALH +L     S PS     L  P   R P VSP      L P P  
Sbjct: 851  LNQHAVVSPP---ALHNALPQ-QPSRPSNRAAALP-PKPARPPAVSPALTQTPLLPQPPM 905

Query: 402  HQGFSRQLSSTSPLAPYPTSQMVSSDRSQLS-------FLPT-EAQAQVSPPPPYPAPQE 453
             Q     L    P AP  TS  +     QL         LP+ + Q+Q  PP P P    
Sbjct: 906  AQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPS 965

Query: 454  LTQPLLQQPRAPEAPAQQ--PQAASSLPQSDFQLLPAQGSS-LTNFFPDVGFD------- 503
            + Q L QQP  P  P  Q  PQ     P     L P Q S+ +    P  G         
Sbjct: 966  VQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPG 1025

Query: 504  QQSMRPGPAFPQQVPLVQQGSRELQDSFHLRPSPYS 539
            QQ   P PA PQQV       R      H +  PYS
Sbjct: 1026 QQPPPPQPAKPQQVIQHHHSPR------HHKSDPYS 1055



 Score = 36.2 bits (82), Expect = 0.092
 Identities = 33/123 (26%), Positives = 44/123 (35%), Gaps = 7/123 (5%)

Query: 430 QLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQSDFQLLPAQ 489
           Q+   P     Q  PPP  P P    Q   Q P  P  P+   QAA ++  S    +  Q
Sbjct: 745 QMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQ 804

Query: 490 GSSLTNFFPDVGFD------QQSMR-PGPAFPQQVPLVQQGSRELQDSFHLRPSPYSNCG 542
              L    P   FD      Q  +  P P  P  +P   + S     + H   SP +   
Sbjct: 805 VPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHN 864

Query: 543 SLP 545
           +LP
Sbjct: 865 ALP 867


>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 49.7 bits (117), Expect = 8e-06
 Identities = 76/303 (25%), Positives = 111/303 (36%), Gaps = 67/303 (22%)

Query: 287  PASLDTTDHHFGSMSVGNSVNNIPAAMTHLGIRSSSGLQSSRSNPSIQATLNKTVLSSSL 346
            P+S D+T    G    GNS +   ++ ++ G+ SSS L  S    S   T     + SS 
Sbjct: 1566 PSSYDST---MGGSICGNSSSQ--SSCSYGGLSSSSSLTQS----SCVVTQQMASMGSSC 1616

Query: 347  NNHPQTSVPNASALHPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSPGPEAHQGFS 406
            +   Q+SV  A+         S+ +P          ++++QPP  P              
Sbjct: 1617 SMMQQSSVQPAANC-------SIKSPQSCVVERPPSNQQQQPPPPP-------------- 1655

Query: 407  RQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPE 466
                   P  P P               P + Q    PPPP   PQ+  QP  QQP  P 
Sbjct: 1656 -------PQQPQPP--------------PPQPQPAPQPPPPQQQPQQQPQPQPQQPPPPP 1694

Query: 467  APAQQPQAA------SSLPQSDFQLLPAQGS----SLTNFFP-DVGFDQQSMRPGPAFPQ 515
             P QQP  +      S  P      +P  GS    S+    P D G    S    P+   
Sbjct: 1695 PPQQQPPLSQCSMNNSFTPAPMIMEIPESGSTGNISIYERIPGDFGAGSYSQ---PSATF 1751

Query: 516  QVPLVQQGSRELQDSFHLRPSPYSNCGSLPNTILPDSSTSLFKDLNS-ALAGLPEVSLNV 574
             +  +QQ +  + D  H  P  +S   +   T +  S+T L +   S  LAG P+    +
Sbjct: 1752 SLAKLQQLTNTIMDP-HAMPYSHSPAVTSYATSVSLSNTGLAQLAPSHPLAGTPQAQATM 1810

Query: 575  DTP 577
              P
Sbjct: 1811 TPP 1813


>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 49.7 bits (117), Expect = 8e-06
 Identities = 76/303 (25%), Positives = 111/303 (36%), Gaps = 67/303 (22%)

Query: 287  PASLDTTDHHFGSMSVGNSVNNIPAAMTHLGIRSSSGLQSSRSNPSIQATLNKTVLSSSL 346
            P+S D+T    G    GNS +   ++ ++ G+ SSS L  S    S   T     + SS 
Sbjct: 1566 PSSYDST---MGGSICGNSSSQ--SSCSYGGLSSSSSLTQS----SCVVTQQMASMGSSC 1616

Query: 347  NNHPQTSVPNASALHPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSPGPEAHQGFS 406
            +   Q+SV  A+         S+ +P          ++++QPP  P              
Sbjct: 1617 SMMQQSSVQPAANC-------SIKSPQSCVVERPPSNQQQQPPPPP-------------- 1655

Query: 407  RQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPE 466
                   P  P P               P + Q    PPPP   PQ+  QP  QQP  P 
Sbjct: 1656 -------PQQPQPP--------------PPQPQPAPQPPPPQQQPQQQPQPQPQQPPPPP 1694

Query: 467  APAQQPQAA------SSLPQSDFQLLPAQGS----SLTNFFP-DVGFDQQSMRPGPAFPQ 515
             P QQP  +      S  P      +P  GS    S+    P D G    S    P+   
Sbjct: 1695 PPQQQPPLSQCSMNNSFTPAPMIMEIPESGSTGNISIYERIPGDFGAGSYSQ---PSATF 1751

Query: 516  QVPLVQQGSRELQDSFHLRPSPYSNCGSLPNTILPDSSTSLFKDLNS-ALAGLPEVSLNV 574
             +  +QQ +  + D  H  P  +S   +   T +  S+T L +   S  LAG P+    +
Sbjct: 1752 SLAKLQQLTNTIMDP-HAMPYSHSPAVTSYATSVSLSNTGLAQLAPSHPLAGTPQAQATM 1810

Query: 575  DTP 577
              P
Sbjct: 1811 TPP 1813


>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 49.7 bits (117), Expect = 8e-06
 Identities = 76/303 (25%), Positives = 111/303 (36%), Gaps = 67/303 (22%)

Query: 287  PASLDTTDHHFGSMSVGNSVNNIPAAMTHLGIRSSSGLQSSRSNPSIQATLNKTVLSSSL 346
            P+S D+T    G    GNS +   ++ ++ G+ SSS L  S    S   T     + SS 
Sbjct: 1566 PSSYDST---MGGSICGNSSSQ--SSCSYGGLSSSSSLTQS----SCVVTQQMASMGSSC 1616

Query: 347  NNHPQTSVPNASALHPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSPGPEAHQGFS 406
            +   Q+SV  A+         S+ +P          ++++QPP  P              
Sbjct: 1617 SMMQQSSVQPAANC-------SIKSPQSCVVERPPSNQQQQPPPPP-------------- 1655

Query: 407  RQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPE 466
                   P  P P               P + Q    PPPP   PQ+  QP  QQP  P 
Sbjct: 1656 -------PQQPQPP--------------PPQPQPAPQPPPPQQQPQQQPQPQPQQPPPPP 1694

Query: 467  APAQQPQAA------SSLPQSDFQLLPAQGS----SLTNFFP-DVGFDQQSMRPGPAFPQ 515
             P QQP  +      S  P      +P  GS    S+    P D G    S    P+   
Sbjct: 1695 PPQQQPPLSQCSMNNSFTPAPMIMEIPESGSTGNISIYERIPGDFGAGSYSQ---PSATF 1751

Query: 516  QVPLVQQGSRELQDSFHLRPSPYSNCGSLPNTILPDSSTSLFKDLNS-ALAGLPEVSLNV 574
             +  +QQ +  + D  H  P  +S   +   T +  S+T L +   S  LAG P+    +
Sbjct: 1752 SLAKLQQLTNTIMDP-HAMPYSHSPAVTSYATSVSLSNTGLAQLAPSHPLAGTPQAQATM 1810

Query: 575  DTP 577
              P
Sbjct: 1811 TPP 1813


>gi|105990535 coagulation factor V precursor [Homo sapiens]
          Length = 2224

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 116/503 (23%), Positives = 188/503 (37%), Gaps = 74/503 (14%)

Query: 137  PRQQPPWKDEKHPGF-----RLTSALNRTNSDSALHTSALSTKPQDPYGGGGQSAWPAPY 191
            PR   P + E +  F     + +  L+++N +++L T    T P   +G      W A  
Sbjct: 1045 PRTFHPLRSEAYNTFSERRLKHSLVLHKSN-ETSLPTDLNQTLPSMDFG------WIASL 1097

Query: 192  MGFCDGENNGHGEVASFPGPLK----EENLLNVPKPLPKQLWETKEIQSLSGRPRSCDV- 246
                   +N  G+ +  PG  +    EE+    P   P Q+  T +    S  P   ++ 
Sbjct: 1098 PDHNQNSSNDTGQASCPPGLYQTVPPEEHYQTFPIQDPDQMHSTSDPSHRSSSPELSEML 1157

Query: 247  ---GGGNAFPHNGQNLGLSPFLGTLNTGGSLPDLTNLHYSTPLPASLDTTDHHFGSMSVG 303
                   +FP +   +  S       T  S PDL+ +  S  L  +  + D    ++S  
Sbjct: 1158 EYDRSHKSFPTDISQMSPSSEHEVWQTVIS-PDLSQVTLSPELSQTNLSPDLSHTTLSPE 1216

Query: 304  NSVNNIPAAMTHLGIR---SSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASAL 360
                N+  A+  + I    S + L    S+ ++   L++T LS  L+    +       L
Sbjct: 1217 LIQRNLSPALGQMPISPDLSHTTLSPDLSHTTLSLDLSQTNLSPELSQTNLSPALGQMPL 1276

Query: 361  HPSLRLFSLS-----------------NPSLSTTNLSGPSRRRQPPVSP----LTLSPGP 399
             P L   +LS                 +P LS TNLS      Q P+SP     TLS   
Sbjct: 1277 SPDLSHTTLSLDFSQTNLSPELSHMTLSPELSQTNLS--PALGQMPISPDLSHTTLSLD- 1333

Query: 400  EAHQGFSRQLSSTS--------PLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPPPPYPAP 451
             +    S +LS T+        PL+P P+   +S D SQ +  P  +Q  +SP     + 
Sbjct: 1334 FSQTNLSPELSQTNLSPALGQMPLSPDPSHTTLSLDLSQTNLSPELSQTNLSPD---LSE 1390

Query: 452  QELTQPLLQQPRAPEAPAQQPQAASSLPQSDF-----QLLPAQGSSLTNFFPDVGF---- 502
              L   L Q P  P+    Q   +  L ++D      Q+  +   S     PD+      
Sbjct: 1391 MPLFADLSQIPLTPD--LDQMTLSPDLGETDLSPNFGQMSLSPDLSQVTLSPDISDTTLL 1448

Query: 503  -DQQSMRPGPAFPQQVPLVQQGSRELQDSFHLRPSPYSNCGSLPNTILPD-SSTSLFKDL 560
             D   + P P    Q+    + S+ L         PY + G +P+   P  + T L K+ 
Sbjct: 1449 PDLSQISPPPDL-DQIFYPSESSQSLLLQEFNESFPYPDLGQMPSPSSPTLNDTFLSKEF 1507

Query: 561  NS-ALAGLPEVSLNVDTPFPLEE 582
            N   + GL +   +     P EE
Sbjct: 1508 NPLVIVGLSKDGTDYIEIIPKEE 1530


>gi|239756297 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 525

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 65/249 (26%), Positives = 93/249 (37%), Gaps = 31/249 (12%)

Query: 270 TGGSLPDLTNLHYSTPLPASLDTTDHHFGSMSVGNSVNNIPAAMTHLGIRSSSGLQSSRS 329
           TG +LP       + PLP          G++  G +V   P  +T          QSSR 
Sbjct: 209 TGPTLPGGRESSEAYPLP--------QLGAIGSGQAVAYGPFVLT----------QSSRP 250

Query: 330 NPSIQATLNKTVLSSSL-NNHPQTSVPNAS--ALHPSLRLFSLSNPSLSTTNLSG----- 381
              +  +L  ++ S  + ++ P T        +  P L   SL  P   T  L+      
Sbjct: 251 TDMLLNSLATSLSSRRMPSSCPMTIFMRCRIRSRSPPLLGSSLGCPRTPTPGLTEGGGTG 310

Query: 382 -PSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQA 440
            PS++R+ P SP T   GP+   G   + S + P  P P     S DR  L       +A
Sbjct: 311 LPSKQRRGP-SPKTELGGPQGSLG---RASLSGPFGPGPQGGPPSRDRRHLGVQIGRVRA 366

Query: 441 QVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQSDFQLLPAQGSSLTNFFPDV 500
            +    PYPA  EL  P  Q   +P+     P         +  L PA  S+L    P  
Sbjct: 367 PLGSALPYPARSELAPPGAQDALSPDPERPCPGTRGVRSGREGLLSPAPRSALGETAPTA 426

Query: 501 GFDQQSMRP 509
            F  +  RP
Sbjct: 427 QFTFRKRRP 435


>gi|50345997 E1A binding protein p300 [Homo sapiens]
          Length = 2414

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 44/161 (27%), Positives = 60/161 (37%), Gaps = 11/161 (6%)

Query: 381  GPSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQA 440
            GPS   +P + P  +   P   QG   Q        P P    V+     L+  P     
Sbjct: 1975 GPSGHLEPGMGPTGMQQQPPWSQGGLPQPQQLQSGMPRPAMMSVAQHGQPLNMAPQPGLG 2034

Query: 441  QV--SPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSL---PQSDFQLLPAQGSSLTN 495
            QV  SP  P    Q+  Q LL+  R+P +P QQ Q  S L   PQ     +  + +   N
Sbjct: 2035 QVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAFIKQRAAKYAN 2094

Query: 496  FFPDVGFDQQSMRPGPAFPQQVPLVQQGSRELQDSFHLRPS 536
              P      Q +   P  PQ  P +Q  +   Q   H  P+
Sbjct: 2095 SNP------QPIPGQPGMPQGQPGLQPPTMPGQQGVHSNPA 2129



 Score = 38.9 bits (89), Expect = 0.014
 Identities = 58/201 (28%), Positives = 77/201 (38%), Gaps = 49/201 (24%)

Query: 301 SVGNSVNNIPAAMTHLGIRSSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASAL 360
           S G +V NIP A             SS   P  QA ++    SSS   +     P +   
Sbjct: 772 SQGMNVTNIPLA------------PSSGQAPVSQAQMS----SSSCPVNSPIMPPGSQGS 815

Query: 361 HPSLRLFSLSNPSLSTTNLSG-PSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYP 419
           H  +    L  P+L   + S  PSR   P  +P ++          ++Q  +T+  AP P
Sbjct: 816 H--IHCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIG---------AQQPPATTIPAPVP 864

Query: 420 TSQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQ--PRAPEAP-AQQPQ--- 473
           T             +P   Q+Q   PPP   P   T  L QQ  P  P AP A QPQ   
Sbjct: 865 TPPA----------MPPGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQQQP 914

Query: 474 -----AASSLPQSDFQLLPAQ 489
                 A+S+P     LLP Q
Sbjct: 915 RSQQSTAASVPTPTAPLLPPQ 935



 Score = 34.3 bits (77), Expect = 0.35
 Identities = 24/81 (29%), Positives = 33/81 (40%), Gaps = 11/81 (13%)

Query: 400  EAHQGFSRQLSSTSPLAPYPTS-------QMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQ 452
            +A+Q    Q    SP+ P P S           S   Q   +P     QV  P P P+P+
Sbjct: 2258 QAYQQRLLQQQMGSPVQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSPQPVPSPR 2317

Query: 453  ELTQPLLQQPRAPEAPAQQPQ 473
              +QP    P +  +P  QPQ
Sbjct: 2318 PQSQP----PHSSPSPRMQPQ 2334


>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
          Length = 1860

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 104/436 (23%), Positives = 160/436 (36%), Gaps = 51/436 (11%)

Query: 190 PYMGFCDGENNGHGEVASFPGPLKEENLLNVPKP-------LPKQLWETKEIQSLSGRPR 242
           P   F  G+ N H     F G L + ++  V +        L KQ  +    QS  G   
Sbjct: 193 PGGSFLFGKMNPHA--VQFEGALCQFSIYPVTQVAHNYCTHLRKQCGQADTYQSPLGPLF 250

Query: 243 SCDVGGGNAFPHNGQNLGL------SPFLGTLNTGGSLPDLTNLHYSTPLPASLDTTDHH 296
           S D G    F  +   LGL      +P LG+L  G   P  T    +   P     T+ H
Sbjct: 251 SQDSGRPFTFQSDLALLGLENLTTATPALGSLPAGRG-PRGTVAPATPTKPQRTSPTNPH 309

Query: 297 FGSMSVGN-----------SVNNIPAAMTHLGIRSSSGL-QSSRSNPSIQATLNKTVLSS 344
              M+VG            S +N    M    +  S+   + + + PS + T  K   S 
Sbjct: 310 -QHMAVGGPAQTPLLPAKLSASNALDPMLPASVGGSTRTPRPAAAQPSQKITATKIPKSL 368

Query: 345 SLN-NHPQTSVPNASALHPSLRLF--SLSNPSLST------TNLSGPSRRRQPPVSPLTL 395
               + P TS+    + HP+ +    S +  +L T      T+   P+R  +P   P+  
Sbjct: 369 PTKPSAPSTSIVPIKSPHPTQKTAPSSFTKSALPTQKQVPPTSRPVPARVSRPAEKPIQR 428

Query: 396 SPG-PEAHQGFSRQLSST--SPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQ 452
           +PG P      +R L  T  S   P PT     +  +  +  P  A+     PPP+ A  
Sbjct: 429 NPGMPRPPPPSTRPLPPTTSSSKKPIPTLARTEAKITSHASKPASARTSTHKPPPFTALS 488

Query: 453 ELTQPLLQQPRAPEAPAQQ--PQAASSLPQSDFQLLPAQGSSLTNFFPDVGFDQQSMRPG 510
               P     R+   PA    P + +S P++    +P  GS+ T     +G  + S + G
Sbjct: 489 SSPAPTPGSTRSTRPPATMVPPTSGTSTPRT-APAVPTPGSAPTGSKKPIG-SEASKKAG 546

Query: 511 PAFPQQVPLVQQGSRELQD----SFHLRPSPYSNCGSLPNT--ILPDSSTSLFKDLNSAL 564
           P    + P+  +  +  +D        RPSP     S   T  ++   +  L        
Sbjct: 547 PKSSPRKPVPLRPGKAARDVPLSDLTTRPSPRQPQPSQQTTPALVLAPAQFLSSSPRPTS 606

Query: 565 AGLPEVSLNVDTPFPL 580
           +G     L   TPFPL
Sbjct: 607 SGYSIFHLAGSTPFPL 622


>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
          Length = 2285

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 53/194 (27%), Positives = 68/194 (35%), Gaps = 17/194 (8%)

Query: 344 SSLNNHPQTSVPNASALHPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTL-SPGPEAH 402
           S      QT   N  + HP  +    S    S T  + PS ++QP   P  L S  P   
Sbjct: 460 SGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYS 519

Query: 403 QGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQP 462
           Q  S+     SP APYP+ Q  +    Q               PPY  PQ  +    QQP
Sbjct: 520 QQPSQPPHQQSP-APYPSQQSTTQQHPQ-------------SQPPYSQPQAQSPYQQQQP 565

Query: 463 RAPEAPAQQPQAASSLPQSDFQLLPAQGSSLTNFFPDVGFDQQSMRPGPAFPQQVPLVQQ 522
           + P       QAA   PQS  Q       S   F P     Q S     +    +   + 
Sbjct: 566 QQPAPSTLSQQAAYPQPQS--QQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKG 623

Query: 523 GSRELQDSFHLRPS 536
           G  ++  S   RPS
Sbjct: 624 GQEDMNLSLQSRPS 637



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 46/178 (25%), Positives = 62/178 (34%), Gaps = 32/178 (17%)

Query: 372  PSLSTTNLSGPSRRRQPPVSPLTLSPGPEAHQGFSRQLSS--TSPLAPYPTSQMVSSDRS 429
            PS   + +  PSR       P       + H  +  Q S+  T   +P+P+ Q     + 
Sbjct: 1311 PSNPDSGMYSPSR-----YPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQ 1365

Query: 430  QLSFLPTEAQAQVSPPPP------YPAPQELTQPLLQQPRAPEA---PAQQPQAASSLPQ 480
            Q ++          PP        Y  P    Q   QQ + P A   PA Q QAA   PQ
Sbjct: 1366 QQNY-KRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPPAQPQPASQQQAAQPSPQ 1424

Query: 481  SDF-----QLLPAQGSSLT---------NFFP-DVGFDQQSMRPGPAFPQQVPLVQQG 523
             D         PA  ++ T         N FP   G D+ S  PG    Q +P    G
Sbjct: 1425 QDVYNQYGNAYPATATAATERRPAGGPQNQFPFQFGRDRVSAPPGTNAQQNMPPQMMG 1482


>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
          Length = 2068

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 53/194 (27%), Positives = 68/194 (35%), Gaps = 17/194 (8%)

Query: 344 SSLNNHPQTSVPNASALHPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTL-SPGPEAH 402
           S      QT   N  + HP  +    S    S T  + PS ++QP   P  L S  P   
Sbjct: 460 SGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYS 519

Query: 403 QGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQP 462
           Q  S+     SP APYP+ Q  +    Q               PPY  PQ  +    QQP
Sbjct: 520 QQPSQPPHQQSP-APYPSQQSTTQQHPQ-------------SQPPYSQPQAQSPYQQQQP 565

Query: 463 RAPEAPAQQPQAASSLPQSDFQLLPAQGSSLTNFFPDVGFDQQSMRPGPAFPQQVPLVQQ 522
           + P       QAA   PQS  Q       S   F P     Q S     +    +   + 
Sbjct: 566 QQPAPSTLSQQAAYPQPQS--QQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKG 623

Query: 523 GSRELQDSFHLRPS 536
           G  ++  S   RPS
Sbjct: 624 GQEDMNLSLQSRPS 637


>gi|157739945 tetratricopeptide repeat, ankyrin repeat and coiled-coil
            containing 2 [Homo sapiens]
          Length = 1990

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 52/210 (24%), Positives = 87/210 (41%), Gaps = 19/210 (9%)

Query: 319  RSSSGLQSSRSNPSIQATLNKTVLSSS-LNNHPQTSVPNASAL-HPSLRLFSLSNPSLST 376
            R S GL   +S PS     +   +SSS L +H      ++S++  P+ + +  ++P+LS 
Sbjct: 1432 RPSQGLPVIQSPPSSPPHRDSAYISSSPLGSHQVFDFRSSSSVGSPTRQTYQSTSPALSP 1491

Query: 377  TNLSGPSRRRQPPVSPL------TLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQ 430
            T+ +   R   P  SP         SP P   QG        SPL   P  +      S 
Sbjct: 1492 THQNSHYRPSPPHTSPAHQGGSYRFSPPPVGGQGKEYPSPPPSPLRRGPQYRASPPAESM 1551

Query: 431  LSFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAP-----EAPAQQPQAASSLPQSDFQL 485
              +     ++Q   P  Y     ++Q L  +P++P     + P Q PQ   ++PQ   +L
Sbjct: 1552 SVY-----RSQSGSPVRYQQETSVSQ-LPGRPKSPLSKMAQRPYQMPQLPVAVPQQGLRL 1605

Query: 486  LPAQGSSLTNFFPDVGFDQQSMRPGPAFPQ 515
             PA+   + +  P       ++ P  A+ Q
Sbjct: 1606 QPAKAQIVRSNQPSPAVHSSTVIPTGAYGQ 1635



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 40/183 (21%), Positives = 69/183 (37%), Gaps = 15/183 (8%)

Query: 305  SVNNIPAAMTHLGIRSSSGLQSSRSNPSIQATLNK--TVLSSSLNNHPQTSVPNASALHP 362
            S +  P   + L +  SS   S   +P +   + +  +V  + +  HP T  P   +   
Sbjct: 1722 SASYYPVCHSKLDLERSS---SQLGSPDVSHLIRRPISVNPNEIKPHPPTPRPLLHSQSV 1778

Query: 363  SLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAP----Y 418
             LR    SN   ST+NL+ P+ R    +  + +   P     + R     SP++P    Y
Sbjct: 1779 GLRFSPSSNSISSTSNLT-PTFRPSSSIQQMEIPLKP----AYERSCDELSPVSPTQGGY 1833

Query: 419  PTSQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSL 478
            P+    S     +  +   A+ Q   P  +   +      +    +P +P   PQ  S  
Sbjct: 1834 PSEPTRSRTTPFMGIIDKTARTQ-QYPHLHQQNRTWAVSSVDTVLSPTSPGNLPQPESFS 1892

Query: 479  PQS 481
            P S
Sbjct: 1893 PPS 1895


>gi|239745228 PREDICTED: hypothetical protein XP_002343392 [Homo
           sapiens]
          Length = 488

 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 47/162 (29%), Positives = 63/162 (38%), Gaps = 12/162 (7%)

Query: 355 PNASALHPSLRLFSLSNPSLSTTNLSG---PSRRRQPPVSPLTLSPGPEAHQGFSRQLSS 411
           PN   L P     SL  P+   T   G   PS++R+ P SP T   GP+   G   + S 
Sbjct: 257 PNVHRLPPPP---SLRTPTPGLTEGGGTGLPSKQRRGP-SPKTELGGPQGSLG---RASL 309

Query: 412 TSPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPEAPAQQ 471
           + P  P P     S DR  L       +  +    PYPA  EL  P  +   +P+     
Sbjct: 310 SGPFGPGPQGGPPSRDRRHLGVQIGRVRVPLGSALPYPARSELAPPGARDALSPDPERPC 369

Query: 472 PQAASSLPQSDFQLLPAQGSSLTNFFPDVGFDQQSMR--PGP 511
           P         +  L PA  S+L    P   F  + +R  PGP
Sbjct: 370 PGTRGVRSGREGLLSPAPRSALGETAPTAQFTFRKVRNPPGP 411


>gi|55750053 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 130/542 (23%), Positives = 192/542 (35%), Gaps = 93/542 (17%)

Query: 11  NPRKFSEKIALHTQRQAEETRAFEQLMTDLTLSRVQFQK-LQQL--RLTQYHGGSLP-NV 66
           N +  SE+I+   + ++EET A ++  T+  L R Q    L  L  R     G S P ++
Sbjct: 68  NKQGRSEEIS---ESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDI 124

Query: 67  SQLRSSASEFQPSFHQADNVRGTRHH--GLVERPSRNRFHPLHRRSGDKPGRQFDGSAFG 124
            Q   S S   PS +   +V        GL + P+R    P H      P          
Sbjct: 125 DQDNRSTS---PSIYSPGSVENDSDSSSGLSQGPAR----PYHPPPLFPP---------- 167

Query: 125 ANYSSQPLDESWPRQQPPWKDEKHPGFRLTSA-LNRTNSDSALHTSALSTKPQDP--YGG 181
              S QP D S PRQ P    E HP    T          S +  +     P  P  Y G
Sbjct: 168 ---SPQPPD-STPRQ-PEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPG 222

Query: 182 GGQSAWPAPYMGFCDGENNGHGEVASFPGPLKEENLLNVPKPLPKQLWETKEIQSLSGRP 241
           G       P MG       G G  +S  GP   +   + P   P  +  +    +   +P
Sbjct: 223 GTGGVLSGPPMG-----PKGGGAASSVGGPNGGKQ--HPPPTTPISVSSSGASGAPPTKP 275

Query: 242 RSCDVGGGNA--------FPHNGQNLGLSPFLGTLNTGGSLPDLTNLHYSTPLPASLDTT 293
            +  VGGGN         FPH   NL   P L  LN   + P       + PLP  L + 
Sbjct: 276 PTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLG---AQPLPGHLPSP 332

Query: 294 DHHFGS------------MSVGNSVNNIPAAMTHLGIRSSSGLQSSRSNPSIQATLNKTV 341
            H  G              ++  S +++P A +           SS S+ S  A+ + + 
Sbjct: 333 -HAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSS 391

Query: 342 LSSSLNNHPQT-SVPNASALHPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSPGPE 400
            SSS +  P + ++P+     P     S+SN          P +  QP +          
Sbjct: 392 SSSSASPFPASQALPSYPHSFPPPTSLSVSNQ---------PPKYTQPSLP--------- 433

Query: 401 AHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQ 460
                S+ + S  P  P P  +++++  +     P    AQ +  PP        Q   Q
Sbjct: 434 -----SQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQ 488

Query: 461 QPRAPEAPAQQPQ---AASSLPQSDFQLLPAQGSSLTNFFP-DVGFDQQSMRPGPAFPQQ 516
           Q +  +   QQ Q     S  P       P +G S  +  P  +     S+RP P  P  
Sbjct: 489 QQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAH 548

Query: 517 VP 518
           +P
Sbjct: 549 LP 550


>gi|55750041 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 130/542 (23%), Positives = 192/542 (35%), Gaps = 93/542 (17%)

Query: 11  NPRKFSEKIALHTQRQAEETRAFEQLMTDLTLSRVQFQK-LQQL--RLTQYHGGSLP-NV 66
           N +  SE+I+   + ++EET A ++  T+  L R Q    L  L  R     G S P ++
Sbjct: 68  NKQGRSEEIS---ESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDI 124

Query: 67  SQLRSSASEFQPSFHQADNVRGTRHH--GLVERPSRNRFHPLHRRSGDKPGRQFDGSAFG 124
            Q   S S   PS +   +V        GL + P+R    P H      P          
Sbjct: 125 DQDNRSTS---PSIYSPGSVENDSDSSSGLSQGPAR----PYHPPPLFPP---------- 167

Query: 125 ANYSSQPLDESWPRQQPPWKDEKHPGFRLTSA-LNRTNSDSALHTSALSTKPQDP--YGG 181
              S QP D S PRQ P    E HP    T          S +  +     P  P  Y G
Sbjct: 168 ---SPQPPD-STPRQ-PEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPG 222

Query: 182 GGQSAWPAPYMGFCDGENNGHGEVASFPGPLKEENLLNVPKPLPKQLWETKEIQSLSGRP 241
           G       P MG       G G  +S  GP   +   + P   P  +  +    +   +P
Sbjct: 223 GTGGVLSGPPMG-----PKGGGAASSVGGPNGGKQ--HPPPTTPISVSSSGASGAPPTKP 275

Query: 242 RSCDVGGGNA--------FPHNGQNLGLSPFLGTLNTGGSLPDLTNLHYSTPLPASLDTT 293
            +  VGGGN         FPH   NL   P L  LN   + P       + PLP  L + 
Sbjct: 276 PTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLG---AQPLPGHLPSP 332

Query: 294 DHHFGS------------MSVGNSVNNIPAAMTHLGIRSSSGLQSSRSNPSIQATLNKTV 341
            H  G              ++  S +++P A +           SS S+ S  A+ + + 
Sbjct: 333 -HAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSS 391

Query: 342 LSSSLNNHPQT-SVPNASALHPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSPGPE 400
            SSS +  P + ++P+     P     S+SN          P +  QP +          
Sbjct: 392 SSSSASPFPASQALPSYPHSFPPPTSLSVSNQ---------PPKYTQPSLP--------- 433

Query: 401 AHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQ 460
                S+ + S  P  P P  +++++  +     P    AQ +  PP        Q   Q
Sbjct: 434 -----SQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQ 488

Query: 461 QPRAPEAPAQQPQ---AASSLPQSDFQLLPAQGSSLTNFFP-DVGFDQQSMRPGPAFPQQ 516
           Q +  +   QQ Q     S  P       P +G S  +  P  +     S+RP P  P  
Sbjct: 489 QQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAH 548

Query: 517 VP 518
           +P
Sbjct: 549 LP 550


>gi|236459851 ubinuclein 2 [Homo sapiens]
          Length = 1347

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 70/313 (22%), Positives = 117/313 (37%), Gaps = 23/313 (7%)

Query: 275  PDLTNLHYSTPLPASLDTTDHHFGSMSVGNSVNN----IPAAMTHLGIRSSSGLQSSRSN 330
            P +  L  STP P +     H   S +V ++  +      A ++ +  +      S  ++
Sbjct: 977  PLMYRLPLSTPSPGNGSQGSHPLVSRTVPSTTTSSNYLAKAMVSQISTQGFKSPFSMAAS 1036

Query: 331  PSIQATLNKTVLSSSLNNHPQTSVPNASALHPSLRLFSLSNPSLSTTNLSGPSRRRQPPV 390
            P + A+         L +   ++ P      PSL     + PS+ST  +S  +   +P V
Sbjct: 1037 PKLAASPKPATSPKPLPSPKPSASPK-----PSLS----AKPSVSTKLISKSNPTPKPTV 1087

Query: 391  SPLTLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPPPPYPA 450
            SP + SP     QG     S+ SP+   P+   +S     L+ LP+   + + P     A
Sbjct: 1088 SPSSSSPNALVAQG--SHSSTNSPVHKQPSGMNISRQSPTLNLLPSSRTSGLPPTKNLQA 1145

Query: 451  PQELTQPLLQQPRAPEAPAQQPQAASSLPQSDFQLLPAQGSSLTNFFPDVGFDQQSMRPG 510
            P +LT                   A ++P S    L + G++ T+     G   Q     
Sbjct: 1146 PSKLTN---SSSTGTVGKNSLSGIAMNVPASRGSNLNSSGANRTSLSGGTGSGTQGATKP 1202

Query: 511  PAFPQQVPLVQQGSRELQDSFHLRPSPYSNCGSLPNTIL--PDSSTSLFKDLNSALAGLP 568
             + P + P    GS  +  S            + P T++  P S T+        L GL 
Sbjct: 1203 LSTPHR-PSTASGSSVVTASVQSTAGASLLANASPLTLMTSPLSVTNQNVTPFGMLGGL- 1260

Query: 569  EVSLNVDTPFPLE 581
             V + +   FPLE
Sbjct: 1261 -VPVTMPFQFPLE 1272



 Score = 34.3 bits (77), Expect = 0.35
 Identities = 32/124 (25%), Positives = 42/124 (33%), Gaps = 11/124 (8%)

Query: 368 SLSNPSLSTTNLSGPSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSD 427
           SLS          GP R  + P  P  L P P        +    +P  P P S      
Sbjct: 11  SLSPVRRREAEYPGPEREPEYPREPPRLEPQPYREPA---RAEPPAPREPAPRSDAQPPS 67

Query: 428 RSQLSFLPTEAQAQVSPP------PPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQS 481
           R +   LP    ++  PP      PP P P     PL  QP  P   A + +     P+ 
Sbjct: 68  REKP--LPQREVSRAEPPMSLQREPPRPEPPPPFPPLPLQPPPPRESASRAEQPPRPPRE 125

Query: 482 DFQL 485
             +L
Sbjct: 126 TVRL 129



 Score = 32.0 bits (71), Expect = 1.7
 Identities = 29/111 (26%), Positives = 42/111 (37%), Gaps = 6/111 (5%)

Query: 428 RSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQSDFQLLP 487
           R +  +   E + +    PP   PQ   +P   +P AP  PA +  A    P S  + LP
Sbjct: 17  RREAEYPGPEREPEYPREPPRLEPQPYREPARAEPPAPREPAPRSDAQ---PPSREKPLP 73

Query: 488 AQGSSLTNFFPDVGFDQQSMRPGPAFP-QQVPLVQQGSRELQDSFHLRPSP 537
            +  S     P +   ++  RP P  P   +PL     RE        P P
Sbjct: 74  QREVSRAE--PPMSLQREPPRPEPPPPFPPLPLQPPPPRESASRAEQPPRP 122


>gi|239750867 PREDICTED: hypothetical protein XP_002347588 [Homo
           sapiens]
          Length = 800

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 43/149 (28%), Positives = 59/149 (39%), Gaps = 9/149 (6%)

Query: 368 SLSNPSLSTTNLSG---PSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPTSQMV 424
           SL  P+   T   G   PS++R+ P SP T   GP+   G   + S + P  P P     
Sbjct: 395 SLRTPTPGLTEGGGTGLPSKQRRGP-SPKTELGGPQGSLG---RASLSGPFGPGPQGGPP 450

Query: 425 SSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQSDFQ 484
           S DR  L       +  +    PYPA  EL  P  +   +P+     P         +  
Sbjct: 451 SRDRRHLGVQIGRVRVPLGSALPYPARSELAPPGARDALSPDPERPCPGTRGVRSGREGL 510

Query: 485 LLPAQGSSLTNFFPDVGFDQQSMR--PGP 511
           L PA  S+L    P   F  + +R  PGP
Sbjct: 511 LSPAPRSALGETAPTAQFTFRKVRNPPGP 539


>gi|55953100 tubby like protein 4 isoform 1 [Homo sapiens]
          Length = 1543

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 53/194 (27%), Positives = 74/194 (38%), Gaps = 21/194 (10%)

Query: 308 NIPAAMTHLGIRSSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASALHPSLRLF 367
           NIP A  H   ++ S  QS     S+ A  N+ V    L N   T+V  A     S   +
Sbjct: 688 NIPIAPIHSSAQAMSPTQSIGLVQSLLA--NQNVQLDVLTNQT-TAVGTAEHAGDSATQY 744

Query: 368 SLSNPSLSTTNLSGPSRR-----RQPPVSPLTLSPGPEA--------HQGFSRQLSSTSP 414
            +SN   +   +   S       + PP  PL+L P P+         H     +    S 
Sbjct: 745 PVSNRYSNPGQVIFGSVEMGRIIQNPP--PLSLPPPPQGPMQLSTVGHGDRDHEHLQKSA 802

Query: 415 LAPYPTSQMVSSDRSQLSFLPTEAQA-QVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQ 473
            A  PT Q+ +   + +   P E Q  +++PPPPYP            P  P  P  QP 
Sbjct: 803 KALRPTPQLAAEGDAVVFSAPQEVQVTKINPPPPYPGTIPAAPTTAAPP--PPLPPPQPP 860

Query: 474 AASSLPQSDFQLLP 487
               L + DF L P
Sbjct: 861 VDVCLKKGDFSLYP 874


>gi|33186895 selenoprotein V [Homo sapiens]
          Length = 346

 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 62/241 (25%), Positives = 91/241 (37%), Gaps = 22/241 (9%)

Query: 346 LNNHPQTSVPNASALHPSLRLFSLSNPSLSTTNLSGPSR-RRQPPVSPLT--LSPGPEAH 402
           +NN  +T  P+++    S+R    S P+ + T L  P+  R + P+  LT  L+P P   
Sbjct: 1   MNNQARTPAPSSARTSTSVRA---STPTRTPTPLRTPTPVRTRTPIRTLTPVLTPSPA-- 55

Query: 403 QGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQP 462
            G S  + + +P A  PT     +       +P  A A +  P P P P     P+    
Sbjct: 56  -GTSPLVLTPAP-AQIPTLVPTPALARIPRLVPPPAPAWIPTPVPTPVPVRNPTPVPTPA 113

Query: 463 RAPEAPAQQP-QAASSLPQSDFQLLPAQGSSLTNFFPDVGFDQQSMRPGPAFPQQVPLVQ 521
           R    P + P  A + L       LP   S L    P        + P P    ++PL+ 
Sbjct: 114 RTLTPPVRVPAPAPAQLLAGIRAALPVLDSYLAPALP--------LDPPPEPAPELPLLP 165

Query: 522 QGSRELQDSFHLRPSPYSNCGSLPN---TILPDSSTSLFKDLNSALAGLPEVSLNVDTPF 578
           +   E   S  L PS  S  G  P    T  P ++ S    L+      P      D P 
Sbjct: 166 EEDPEPAPSLKLIPSVSSEAGPAPGPLPTRTPLAANSPGPTLDFTFRADPSAIGLADPPI 225

Query: 579 P 579
           P
Sbjct: 226 P 226


>gi|112421108 capicua homolog [Homo sapiens]
          Length = 1608

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 57/289 (19%), Positives = 97/289 (33%), Gaps = 30/289 (10%)

Query: 325  QSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASALHPSLRLFSLSNPSLSTTNLSGPSR 384
            Q S++ PS+  T+  +    +    P+     A+A       F  +     T +L  P  
Sbjct: 1110 QPSQAPPSLVYTVATSTTPPAATILPKGPPAPATATPAPTSPFPSATAGSMTYSLVAPKA 1169

Query: 385  RRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSP 444
            +R  P +P  +     +    S +  ++    P P   +      + +   +E + Q +P
Sbjct: 1170 QRPSPKAPQKVKAAIASIPVGSFEAGASGRPGPAPRQPLEPGPVREPTAPESELEGQPTP 1229

Query: 445  PPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQSDFQLLPAQGSSLTNFFPDVGFDQ 504
            P P P P+  T      P  P  P  + + ++  P++     P+  S      P  G + 
Sbjct: 1230 PAPPPLPETWTPTARSSPPLP--PPAEERTSAKGPETMASKFPSSSSDWR--VPGQGLEN 1285

Query: 505  QSMRPGPAFPQQVPLVQQGSRELQDS-------------------FHLRPSPYSNC-GSL 544
            +   P P  P   P V  G      S                     +RP P      S+
Sbjct: 1286 RGEPPTPPSPAPAPAVAPGGSSESSSGRAAGDTPERKEAAGTGKKVKVRPPPLKKTFDSV 1345

Query: 545  PNTILPDSSTSLFKDLNSALAGLPEVSLNVDTPFPLEEELQIEPLSLDG 593
             N +L +       D     A LPE       P P  + L   P ++ G
Sbjct: 1346 DNRVLSE------VDFEERFAELPEFRPEEVLPSPTLQSLATSPRAILG 1388


>gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]
          Length = 2089

 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 55/213 (25%), Positives = 77/213 (36%), Gaps = 26/213 (12%)

Query: 284  TPLPASLDTTDHHFGSMSVGNSVNNIPAAMTHLGIRSSSGLQSSRSNPSIQATLNKTVLS 343
            TP P S  TT       SV N  + +P A       S+S  Q     P+ +AT  +   S
Sbjct: 1343 TPKPTSR-TTRSRTNMSSVKNPESTVPIAPELPP--STSTEQPVTPEPTSRATRGRKNRS 1399

Query: 344  SSLNNHPQTSVPNASALHPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSPGPEAHQ 403
            S     P+T VP A  L PS        P  ++    G + R         +   PE   
Sbjct: 1400 SGKT--PETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPE--- 1454

Query: 404  GFSRQLSSTSPLAPYPTSQMV--SSDRSQL----SFLPTEAQAQVSPPPPYPAPQELTQP 457
                  S+  P+ P PTSQ     +DRS +    + +PT  + Q S     P   E T  
Sbjct: 1455 -LQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEPTSR 1513

Query: 458  LLQ-----------QPRAPEAPAQQPQAASSLP 479
              +           +   P AP  QP  ++  P
Sbjct: 1514 TTRGRKNRSSVKTPETVVPAAPELQPSTSTDQP 1546



 Score = 38.1 bits (87), Expect = 0.024
 Identities = 41/169 (24%), Positives = 64/169 (37%), Gaps = 10/169 (5%)

Query: 320  SSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASALHPSLRLFSLSNPSLSTTNL 379
            S+S  Q     P+ QAT  +T  SS     P+T VP A  L PS        P  ++   
Sbjct: 1417 STSTDQPVTPEPTSQATRGRTNRSSVKT--PETVVPTAPELQPSTSTDQPVTPEPTSQAT 1474

Query: 380  SGPSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQ 439
             G + R         +   PE         S+  P+   PTS+     +++ S    E  
Sbjct: 1475 RGRTDRSSVKTPETVVPTAPE----LQASASTDQPVTSEPTSRTTRGRKNRSSVKTPET- 1529

Query: 440  AQVSPPPPYPAPQELT-QPLLQQPRAPEAPAQQPQAASSLPQSDFQLLP 487
              V P  P   P   T QP+  +P +     +  +++   P+S   + P
Sbjct: 1530 --VVPAAPELQPSTSTDQPVTPEPTSRATRGRTNRSSVKTPESIVPIAP 1576



 Score = 37.7 bits (86), Expect = 0.032
 Identities = 43/164 (26%), Positives = 68/164 (41%), Gaps = 12/164 (7%)

Query: 320  SSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASALHPSLRLFSLSNPSLSTTNL 379
            S+S  Q   S P+ QAT  +   SS     P+  VP A  L PS        P    T+ 
Sbjct: 1253 STSTDQPVTSEPTYQATRGRKNRSSVKT--PEPVVPTAPELRPSTSTDRPVTPK--PTSR 1308

Query: 380  SGPSRRRQPPV-SPLTLSP-GPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTE 437
            +  SR     V +P T+ P  PE         S+  P+ P PTS+   S  +  S    E
Sbjct: 1309 TTRSRTNMSSVKTPETVVPTAPE----LQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPE 1364

Query: 438  AQAQVSPPPPYPAPQELTQPLLQQPRAPEAPAQQPQAASSLPQS 481
            +   ++P  P     E  QP+  +P +     ++ +++   P++
Sbjct: 1365 STVPIAPELPPSTSTE--QPVTPEPTSRATRGRKNRSSGKTPET 1406



 Score = 31.2 bits (69), Expect = 3.0
 Identities = 38/152 (25%), Positives = 57/152 (37%), Gaps = 23/152 (15%)

Query: 331  PSIQATLNKTVLSSSLNNHPQTSVPNASALHPSLRLFSLSNPSLSTTNLSGPSRRRQPPV 390
            PSI+ T+ KT    S               HP         P + T   S     R  P 
Sbjct: 1072 PSIKPTVRKTRQDGSQEAPEAPLSSELEPFHPK--------PKIRTRKSS-----RMTPF 1118

Query: 391  SPLTLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPPPPYPA 450
             P T S  PE H       S+  P+ P PTSQ   + RS+ +    +    V P  P   
Sbjct: 1119 -PAT-SAAPEPHPS----TSTAQPVTPKPTSQ---ATRSRTNRSSVKTPEPVVPTAPELQ 1169

Query: 451  PQELT-QPLLQQPRAPEAPAQQPQAASSLPQS 481
            P   T QP+  +P +     ++ +++   P++
Sbjct: 1170 PSTSTDQPVTSEPTSQVTRGRKSRSSVKTPET 1201



 Score = 29.6 bits (65), Expect = 8.6
 Identities = 34/130 (26%), Positives = 49/130 (37%), Gaps = 7/130 (5%)

Query: 320  SSSGLQSSRSNPSIQATLNKTVLSSSLNNHPQTSVPNASALHPSLRLFSLSNPSLSTTNL 379
            S+S  Q   S P+ + T  +   SS     P+T VP A  L PS        P  ++   
Sbjct: 1499 SASTDQPVTSEPTSRTTRGRKNRSSVKT--PETVVPAAPELQPSTSTDQPVTPEPTSRAT 1556

Query: 380  SGPSRRRQPPVSPLTLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQ 439
             G + R         +   PE     SR    T    P PTS+  +  R+  S + T   
Sbjct: 1557 RGRTNRSSVKTPESIVPIAPELQPSTSRNQLVT----PEPTSR-ATRCRTNRSSVKTPEP 1611

Query: 440  AQVSPPPPYP 449
               + P P+P
Sbjct: 1612 VVPTAPEPHP 1621


>gi|237757326 synaptojanin 1 isoform d [Homo sapiens]
          Length = 1526

 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 67/275 (24%), Positives = 100/275 (36%), Gaps = 23/275 (8%)

Query: 350  PQTSVPNASA-LHPSLRLFSLSNPSLSTTNLSGP--SRRRQPPVSPLTLSPGPEAHQGFS 406
            PQ   P++S+ L  S      ++P  S T   GP  S   +P  +P + +PGP + Q   
Sbjct: 1022 PQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAP-SRTPGPPSAQSSP 1080

Query: 407  RQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPPPPYPAPQELTQPLLQQPRAPE 466
                  +PL     +Q +   R      P     + +PP   P P   +QP  Q   A  
Sbjct: 1081 IDAQPATPLPQKDPAQPLEPKRPPPP-RPVAPPTRPAPPQRPPPPSGRSQPSPQAGLAGP 1139

Query: 467  APAQQPQAASSLP--------------QSDFQLLPAQGSSLTNFFPDVGFDQQSMRPGPA 512
             PA    A  ++P               S  +L P   S  +       F  + ++P  A
Sbjct: 1140 GPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAA 1199

Query: 513  FPQQVPLVQQGSRELQDSFHLRPSPYSNCGSLPNTILPDSSTSLFK---DLNSALAGLPE 569
            FP Q  L     R LQ+      +P    G  PN   P       +    L S  +  P+
Sbjct: 1200 FPPQSSLPPPAQR-LQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQ 1258

Query: 570  VSLNVDTPFPLEEELQIEPLSLDGLNMLSDSSMGL 604
            V  N  +    E  L+I+P      N+L+ S   L
Sbjct: 1259 VKTNGISDGKRESPLKIDPFEDLSFNLLAVSKAQL 1293


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.129    0.380 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,143,101
Number of Sequences: 37866
Number of extensions: 1679878
Number of successful extensions: 10177
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 116
Number of HSP's successfully gapped in prelim test: 787
Number of HSP's that attempted gapping in prelim test: 7422
Number of HSP's gapped (non-prelim): 2419
length of query: 618
length of database: 18,247,518
effective HSP length: 108
effective length of query: 510
effective length of database: 14,157,990
effective search space: 7220574900
effective search space used: 7220574900
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.