Guide to the Human Genome
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Search of human proteins with 110349727

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|110349727 nuclear cap binding protein subunit 2, 20kDa
isoform 2 [Homo sapiens]
         (103 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|110349727 nuclear cap binding protein subunit 2, 20kDa isofor...   214   1e-56
gi|19923387 nuclear cap binding protein subunit 2, 20kDa isoform...   183   2e-47
gi|239757879 PREDICTED: similar to Nuclear cap-binding protein s...   104   1e-23
gi|5803137 RNA binding motif protein 3 [Homo sapiens]                  34   0.022
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]     31   0.24 
gi|22094125 zinc finger protein 28 [Homo sapiens]                      30   0.31 
gi|14702180 eukaryotic translation initiation factor 4H isoform ...    30   0.41 
gi|15826852 acyl-Coenzyme A binding domain containing 3 [Homo sa...    30   0.41 
gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens]           30   0.53 
gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens]          30   0.53 
gi|109452587 family with sequence similarity 98, member B isofor...    30   0.53 
gi|4502847 cold inducible RNA binding protein [Homo sapiens]           28   1.2  
gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]     28   2.0  
gi|103471997 DNA-directed RNA polymerase I A [Homo sapiens]            27   2.6  
gi|4759098 splicing factor, arginine/serine-rich 10 [Homo sapiens]     27   4.5  
gi|4505101 microtubule-associated protein 7 [Homo sapiens]             27   4.5  
gi|9558733 transformer-2 alpha [Homo sapiens]                          26   5.9  
gi|169161779 PREDICTED: similar to nucleophosmin 1 [Homo sapiens]      26   7.7  
gi|169161624 PREDICTED: similar to nucleophosmin 1 [Homo sapiens]      26   7.7  
gi|169162829 PREDICTED: similar to nucleophosmin 1 [Homo sapiens]      26   7.7  
gi|5031795 inhibin beta C chain preproprotein [Homo sapiens]           26   7.7  
gi|153945734 teashirt zinc finger homeobox 2 [Homo sapiens]            26   7.7  

>gi|110349727 nuclear cap binding protein subunit 2, 20kDa isoform 2
           [Homo sapiens]
          Length = 103

 Score =  214 bits (545), Expect = 1e-56
 Identities = 103/103 (100%), Positives = 103/103 (100%)

Query: 1   MSGGLLKALRSDSYVELSQYRDQHFRGDNEEQEKLLKKSYAENAMRYINGTRLDDRIIRT 60
           MSGGLLKALRSDSYVELSQYRDQHFRGDNEEQEKLLKKSYAENAMRYINGTRLDDRIIRT
Sbjct: 1   MSGGLLKALRSDSYVELSQYRDQHFRGDNEEQEKLLKKSYAENAMRYINGTRLDDRIIRT 60

Query: 61  DWDAGFKEGRQYGRGRSGGQVRDEYRQDYDAGRGGYGKLAQNQ 103
           DWDAGFKEGRQYGRGRSGGQVRDEYRQDYDAGRGGYGKLAQNQ
Sbjct: 61  DWDAGFKEGRQYGRGRSGGQVRDEYRQDYDAGRGGYGKLAQNQ 103


>gi|19923387 nuclear cap binding protein subunit 2, 20kDa isoform 1
           [Homo sapiens]
          Length = 156

 Score =  183 bits (465), Expect = 2e-47
 Identities = 100/156 (64%), Positives = 102/156 (65%), Gaps = 53/156 (33%)

Query: 1   MSGGLLKALRSDSYVELSQYRDQHFRGDNEEQEKLLK----------------------- 37
           MSGGLLKALRSDSYVELSQYRDQHFRGDNEEQEKLLK                       
Sbjct: 1   MSGGLLKALRSDSYVELSQYRDQHFRGDNEEQEKLLKKSCTLYVGNLSFYTTEEQIYELF 60

Query: 38  ------------------------------KSYAENAMRYINGTRLDDRIIRTDWDAGFK 67
                                         ++ AENAMRYINGTRLDDRIIRTDWDAGFK
Sbjct: 61  SKSGDIKKIIMGLDKMKKTACGFCFVEYYSRADAENAMRYINGTRLDDRIIRTDWDAGFK 120

Query: 68  EGRQYGRGRSGGQVRDEYRQDYDAGRGGYGKLAQNQ 103
           EGRQYGRGRSGGQVRDEYRQDYDAGRGGYGKLAQNQ
Sbjct: 121 EGRQYGRGRSGGQVRDEYRQDYDAGRGGYGKLAQNQ 156


>gi|239757879 PREDICTED: similar to Nuclear cap-binding protein
           subunit 2-like [Homo sapiens]
          Length = 114

 Score =  104 bits (260), Expect = 1e-23
 Identities = 55/109 (50%), Positives = 69/109 (63%), Gaps = 13/109 (11%)

Query: 6   LKALRSDSYVELSQYRDQHFRGDNEEQEKLLKKSYAENAMRY-------------INGTR 52
           LK L  D  +ELS YRD  F G   +QEKLLK+S   N                 + GT 
Sbjct: 5   LKILCKDPALELSCYRDHQFSGRKFQQEKLLKESSTLNMGNLSFYTTEEKIHELLLTGTC 64

Query: 53  LDDRIIRTDWDAGFKEGRQYGRGRSGGQVRDEYRQDYDAGRGGYGKLAQ 101
           LD+ II TDWD GF+EG+QYGRG+SGGQVRDE+R+D+ +GRGG+G+  Q
Sbjct: 65  LDEWIICTDWDVGFREGQQYGRGKSGGQVRDEFREDFHSGRGGFGRQTQ 113


>gi|5803137 RNA binding motif protein 3 [Homo sapiens]
          Length = 157

 Score = 34.3 bits (77), Expect = 0.022
 Identities = 26/68 (38%), Positives = 32/68 (47%), Gaps = 10/68 (14%)

Query: 40  YAENAMRYINGTRLDDRIIRTDWDAGFKEGRQ------YGRGRS----GGQVRDEYRQDY 89
           +A  AMR +NG  LD R IR D       G +      +GRGRS    GG       + Y
Sbjct: 59  HASVAMRAMNGESLDGRQIRVDHAGKSARGTRGGGFGAHGRGRSYSRGGGDQGYGSGRYY 118

Query: 90  DAGRGGYG 97
           D+  GGYG
Sbjct: 119 DSRPGGYG 126


>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
          Length = 494

 Score = 30.8 bits (68), Expect = 0.24
 Identities = 24/86 (27%), Positives = 38/86 (44%), Gaps = 2/86 (2%)

Query: 20  YRDQHFRGDNEEQEKLLKKSYAENAMRYINGTRLDDRIIRTDWD-AGFKEGRQYGRGRSG 78
           Y D H    NE   + +  S  + A+  ++GT ++ R IR   D  G +  R Y R RS 
Sbjct: 132 YADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSH 191

Query: 79  GQVRDEYRQDYDA-GRGGYGKLAQNQ 103
            + R   R    +  R G  K + ++
Sbjct: 192 SRSRSRSRHSRKSRSRSGSSKSSHSK 217



 Score = 26.2 bits (56), Expect = 5.9
 Identities = 23/87 (26%), Positives = 35/87 (40%), Gaps = 10/87 (11%)

Query: 13 SYVELSQYRDQHFRGDNEEQEKLLKKSY----------AENAMRYINGTRLDDRIIRTDW 62
          SY    +  ++ F+G  +  E  LK  Y          A++A+  +NG  L    +  + 
Sbjct: 10 SYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGKDLCGERVIVEH 69

Query: 63 DAGFKEGRQYGRGRSGGQVRDEYRQDY 89
            G +    YG GRSG   R   R  Y
Sbjct: 70 ARGPRRDGSYGSGRSGYGYRRSGRDKY 96


>gi|22094125 zinc finger protein 28 [Homo sapiens]
          Length = 868

 Score = 30.4 bits (67), Expect = 0.31
 Identities = 18/52 (34%), Positives = 27/52 (51%), Gaps = 1/52 (1%)

Query: 26  RGDNEEQEKLLKK-SYAENAMRYINGTRLDDRIIRTDWDAGFKEGRQYGRGR 76
           R  +E QE   K+ SYAE      + T+LD    R +WD+ +  GR+   G+
Sbjct: 302 RSVHETQELFPKQDSYAEGVTDRTSNTKLDCSSFRENWDSDYVFGRKLAVGQ 353


>gi|14702180 eukaryotic translation initiation factor 4H isoform 2
           [Homo sapiens]
          Length = 228

 Score = 30.0 bits (66), Expect = 0.41
 Identities = 19/54 (35%), Positives = 27/54 (50%), Gaps = 1/54 (1%)

Query: 42  ENAMRYINGTRLDDRIIRTDWDAGFKEGRQYGRGRSGGQVRDEYRQDYDAGRGG 95
           + A+ Y +G  L DR +R D   G K+ +     R GG     +R D+  GRGG
Sbjct: 96  KEALTY-DGALLGDRSLRVDIAEGRKQDKGGFGFRKGGPDDRGFRDDFLGGRGG 148


>gi|15826852 acyl-Coenzyme A binding domain containing 3 [Homo
           sapiens]
          Length = 528

 Score = 30.0 bits (66), Expect = 0.41
 Identities = 12/44 (27%), Positives = 27/44 (61%)

Query: 5   LLKALRSDSYVELSQYRDQHFRGDNEEQEKLLKKSYAENAMRYI 48
           ++ AL S + V+  QY  Q + G+ E+Q+ L+++   ++  +Y+
Sbjct: 246 IMAALNSQTAVQFQQYAAQQYPGNYEQQQILIRQLQEQHYQQYM 289


>gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens]
          Length = 589

 Score = 29.6 bits (65), Expect = 0.53
 Identities = 27/82 (32%), Positives = 37/82 (45%), Gaps = 13/82 (15%)

Query: 13  SYVELSQYRDQHFRGDNEEQEKLLKKSYAENAMRYINGTRLDDRIIRTDWDAGFKEGRQY 72
           SY E S Y  QH   D+  Q +   +SY      Y + T+ D    R D     ++ R Y
Sbjct: 125 SYDEQSNYDQQH---DSYSQNQ---QSYHSQRENYSHHTQDD----RRDVSRYGEDNRGY 174

Query: 73  GRGRSGGQVRDEYRQDYDAGRG 94
           G  + GG+ R  Y +D   GRG
Sbjct: 175 GGSQGGGRGRGGYDKD---GRG 193



 Score = 25.8 bits (55), Expect = 7.7
 Identities = 12/26 (46%), Positives = 13/26 (50%)

Query: 72  YGRGRSGGQVRDEYRQDYDAGRGGYG 97
           YG  RSGG    +    Y   RGGYG
Sbjct: 546 YGGDRSGGGYGGDRGGGYGGDRGGYG 571


>gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens]
          Length = 592

 Score = 29.6 bits (65), Expect = 0.53
 Identities = 27/82 (32%), Positives = 37/82 (45%), Gaps = 13/82 (15%)

Query: 13  SYVELSQYRDQHFRGDNEEQEKLLKKSYAENAMRYINGTRLDDRIIRTDWDAGFKEGRQY 72
           SY E S Y  QH   D+  Q +   +SY      Y + T+ D    R D     ++ R Y
Sbjct: 128 SYDEQSNYDQQH---DSYSQNQ---QSYHSQRENYSHHTQDD----RRDVSRYGEDNRGY 177

Query: 73  GRGRSGGQVRDEYRQDYDAGRG 94
           G  + GG+ R  Y +D   GRG
Sbjct: 178 GGSQGGGRGRGGYDKD---GRG 196



 Score = 25.8 bits (55), Expect = 7.7
 Identities = 12/26 (46%), Positives = 13/26 (50%)

Query: 72  YGRGRSGGQVRDEYRQDYDAGRGGYG 97
           YG  RSGG    +    Y   RGGYG
Sbjct: 549 YGGDRSGGGYGGDRGGGYGGDRGGYG 574


>gi|109452587 family with sequence similarity 98, member B isoform 1
           [Homo sapiens]
          Length = 433

 Score = 29.6 bits (65), Expect = 0.53
 Identities = 16/36 (44%), Positives = 19/36 (52%), Gaps = 1/36 (2%)

Query: 62  WDAGFKEGRQYGRGRSGGQVRDEYRQDYDAGRGGYG 97
           W  G   G  +G G  GG+   + R DY  GRGGYG
Sbjct: 366 WGGGGGGGGGWGGGGGGGRGGFQGRGDY-GGRGGYG 400


>gi|4502847 cold inducible RNA binding protein [Homo sapiens]
          Length = 172

 Score = 28.5 bits (62), Expect = 1.2
 Identities = 26/78 (33%), Positives = 34/78 (43%), Gaps = 22/78 (28%)

Query: 41  AENAMRYINGTRLDDRIIRTDWDAG--------------------FKEGRQYGRGRS-GG 79
           A++AM  +NG  +D R IR D  AG                    F+ GR  GRG S GG
Sbjct: 60  AKDAMMAMNGKSVDGRQIRVD-QAGKSSDNRSRGYRGGSAGGRGFFRGGRGRGRGFSRGG 118

Query: 80  QVRDEYRQDYDAGRGGYG 97
             R      +++  GGYG
Sbjct: 119 GDRGYGGNRFESRSGGYG 136


>gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]
          Length = 614

 Score = 27.7 bits (60), Expect = 2.0
 Identities = 14/30 (46%), Positives = 18/30 (60%), Gaps = 1/30 (3%)

Query: 68  EGRQYGRGRSGGQVRDEYRQDYDAG-RGGY 96
           E R  GR R  G ++D+ R  Y AG RGG+
Sbjct: 476 EDRGSGRSRGRGGMKDDRRDRYSAGKRGGF 505


>gi|103471997 DNA-directed RNA polymerase I A [Homo sapiens]
          Length = 1720

 Score = 27.3 bits (59), Expect = 2.6
 Identities = 16/59 (27%), Positives = 25/59 (42%)

Query: 33   EKLLKKSYAENAMRYINGTRLDDRIIRTDWDAGFKEGRQYGRGRSGGQVRDEYRQDYDA 91
            E + KK+   +A R +N  R   R +    + G   G Q G     G + D   ++ DA
Sbjct: 1352 ESIKKKNNKASAFRNVNTRRATQRDLDNAGELGRSRGEQEGDEEEEGHIVDAEAEEGDA 1410


>gi|4759098 splicing factor, arginine/serine-rich 10 [Homo sapiens]
          Length = 288

 Score = 26.6 bits (57), Expect = 4.5
 Identities = 25/77 (32%), Positives = 28/77 (36%), Gaps = 20/77 (25%)

Query: 41  AENAMRYINGTRLDDRIIRTDWD---------AGFKEGR-QYGRGR----------SGGQ 80
           A+ A    NG  LD R IR D+           G   GR  YG  R           G  
Sbjct: 172 AKEAKERANGMELDGRRIRVDFSITKRPHTPTPGIYMGRPTYGSSRRRDYYDRGYDRGYD 231

Query: 81  VRDEYRQDYDAGRGGYG 97
            RD Y + Y  G GG G
Sbjct: 232 DRDYYSRSYRGGGGGGG 248


>gi|4505101 microtubule-associated protein 7 [Homo sapiens]
          Length = 749

 Score = 26.6 bits (57), Expect = 4.5
 Identities = 14/38 (36%), Positives = 21/38 (55%), Gaps = 2/38 (5%)

Query: 19  QYRDQHFRGDNEEQEKLLKKSYAENAMRYINGTRLDDR 56
           Q R++HF+   EEQE+L +K   E  M+    T   D+
Sbjct: 583 QEREKHFQ--REEQERLERKKRLEEIMKRTRRTEATDK 618


>gi|9558733 transformer-2 alpha [Homo sapiens]
          Length = 282

 Score = 26.2 bits (56), Expect = 5.9
 Identities = 23/77 (29%), Positives = 28/77 (36%), Gaps = 21/77 (27%)

Query: 41  AENAMRYINGTRLDDRIIRTDW--------------------DAGFKEGRQYGRGRSGGQ 80
           ++ AM   NG  LD R IR D+                      G   G   G G  GG+
Sbjct: 173 SKEAMERANGMELDGRRIRVDYSITKRAHTPTPGIYMGRPTHSGGGGGGGGGGGGGGGGR 232

Query: 81  VRDE-YRQDYDAGRGGY 96
            RD  Y + YD G   Y
Sbjct: 233 RRDSYYDRGYDRGYDRY 249


>gi|169161779 PREDICTED: similar to nucleophosmin 1 [Homo sapiens]
          Length = 186

 Score = 25.8 bits (55), Expect = 7.7
 Identities = 13/34 (38%), Positives = 19/34 (55%), Gaps = 3/34 (8%)

Query: 6  LKALRSDSYV---ELSQYRDQHFRGDNEEQEKLL 36
          +  LR  +Y+   EL   +D HF+ DN+E E  L
Sbjct: 5  MSPLRPQNYLFGCELKADKDDHFKVDNDENEHQL 38


>gi|169161624 PREDICTED: similar to nucleophosmin 1 [Homo sapiens]
          Length = 186

 Score = 25.8 bits (55), Expect = 7.7
 Identities = 13/34 (38%), Positives = 19/34 (55%), Gaps = 3/34 (8%)

Query: 6  LKALRSDSYV---ELSQYRDQHFRGDNEEQEKLL 36
          +  LR  +Y+   EL   +D HF+ DN+E E  L
Sbjct: 5  MSPLRPQNYLFGCELKADKDDHFKVDNDENEHQL 38


>gi|169162829 PREDICTED: similar to nucleophosmin 1 [Homo sapiens]
          Length = 186

 Score = 25.8 bits (55), Expect = 7.7
 Identities = 13/34 (38%), Positives = 19/34 (55%), Gaps = 3/34 (8%)

Query: 6  LKALRSDSYV---ELSQYRDQHFRGDNEEQEKLL 36
          +  LR  +Y+   EL   +D HF+ DN+E E  L
Sbjct: 5  MSPLRPQNYLFGCELKADKDDHFKVDNDENEHQL 38


>gi|5031795 inhibin beta C chain preproprotein [Homo sapiens]
          Length = 352

 Score = 25.8 bits (55), Expect = 7.7
 Identities = 19/44 (43%), Positives = 25/44 (56%), Gaps = 2/44 (4%)

Query: 28  DNEEQEKLLKKSYAENAMRYINGTRLDDRIIRTDWDAGFKEGRQ 71
           DN EQE  +  S+AE  +  IN TRLD     +D  AG +E +Q
Sbjct: 90  DNREQECEII-SFAETGLSTINQTRLDFH-FSSDRTAGDREVQQ 131


>gi|153945734 teashirt zinc finger homeobox 2 [Homo sapiens]
          Length = 1034

 Score = 25.8 bits (55), Expect = 7.7
 Identities = 12/37 (32%), Positives = 24/37 (64%), Gaps = 2/37 (5%)

Query: 12  DSYVELSQYRDQ--HFRGDNEEQEKLLKKSYAENAMR 46
           D+ VEL+ + ++  H++ DN +++KL   SY++   R
Sbjct: 225 DTLVELTVHMNETGHYQDDNRKKDKLRPTSYSKPRKR 261


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.136    0.396 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,839,420
Number of Sequences: 37866
Number of extensions: 152527
Number of successful extensions: 345
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 321
Number of HSP's gapped (non-prelim): 32
length of query: 103
length of database: 18,247,518
effective HSP length: 74
effective length of query: 29
effective length of database: 15,445,434
effective search space: 447917586
effective search space used: 447917586
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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