Search of human proteins with 156086724

Search of human proteins with 156086724

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|156086724 GTPase activating Rap/RanGAP domain-like 4 isoform
1 [Homo sapiens]
         (730 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|156086724 GTPase activating Rap/RanGAP domain-like 4 isoform ...  1472   0.0  
gi|156086740 GTPase activating Rap/RanGAP domain-like 4 isoform ...  1431   0.0  
gi|224809578 RAP1 GTPase activating protein isoform a [Homo sapi...   667   0.0  
gi|224809582 RAP1 GTPase activating protein isoform c [Homo sapi...   642   0.0  
gi|224809573 RAP1 GTPase activating protein isoform b [Homo sapi...   633   0.0  
gi|71143119 signal-induced proliferation-associated 1 like 3 [Ho...   234   2e-61
gi|7662126 signal-induced proliferation-associated 1 like 1 [Hom...   231   2e-60
gi|112421013 signal-induced proliferation-associated 1 like 2 [H...   230   4e-60
gi|206725526 signal-induced proliferation-associated protein 1 [...   222   1e-57
gi|206725523 signal-induced proliferation-associated protein 1 [...   222   1e-57
gi|207448705 GTPase activating Rap/RanGAP domain-like 3 [Homo sa...   222   1e-57
gi|118600961 akt substrate AS250 [Homo sapiens]                        77   6e-14
gi|51230412 GTPase activating Rap/RanGAP domain-like 1 isoform 2...    75   2e-13
gi|51226124 GTPase activating Rap/RanGAP domain-like 1 isoform 1...    75   2e-13
gi|116256350 tuberous sclerosis 2 isoform 4 [Homo sapiens]             68   3e-11
gi|116256352 tuberous sclerosis 2 isoform 1 [Homo sapiens]             68   3e-11
gi|167412124 tuberous sclerosis 2 isoform 5 [Homo sapiens]             68   3e-11
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]         49   1e-05
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        49   2e-05
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          48   3e-05
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          48   3e-05
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          48   3e-05
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        47   8e-05
gi|239758148 PREDICTED: similar to mucin 11 [Homo sapiens]             42   0.002
gi|239752490 PREDICTED: similar to Mucin-12 [Homo sapiens]             42   0.002
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ...    42   0.002
gi|157384984 transducin-like enhancer protein 3 isoform c [Homo ...    41   0.003
gi|42518068 trans-golgi network protein 2 [Homo sapiens]               41   0.005
gi|161016767 mucin 21 [Homo sapiens]                                   41   0.005
gi|158854042 hypothetical protein LOC222183 [Homo sapiens]             40   0.006

>gi|156086724 GTPase activating Rap/RanGAP domain-like 4 isoform 1
           [Homo sapiens]
          Length = 730

 Score = 1472 bits (3810), Expect = 0.0
 Identities = 730/730 (100%), Positives = 730/730 (100%)

Query: 1   MFGRKRSVSFGGFGWIDKTMLASLKVKKQELANSSDATLPDRPLSPPLTAPPTMKSSEFF 60
           MFGRKRSVSFGGFGWIDKTMLASLKVKKQELANSSDATLPDRPLSPPLTAPPTMKSSEFF
Sbjct: 1   MFGRKRSVSFGGFGWIDKTMLASLKVKKQELANSSDATLPDRPLSPPLTAPPTMKSSEFF 60

Query: 61  EMLEKMQGIKLEEQKPGPQKNKDDYIPYPSIDEVVEKGGPYPQVILPQFGGYWIEDPENV 120
           EMLEKMQGIKLEEQKPGPQKNKDDYIPYPSIDEVVEKGGPYPQVILPQFGGYWIEDPENV
Sbjct: 61  EMLEKMQGIKLEEQKPGPQKNKDDYIPYPSIDEVVEKGGPYPQVILPQFGGYWIEDPENV 120

Query: 121 GTPTSLGSSICEEEEEDNLSPNTFGYKLECKGEARAYRRHFLGKDHLNFYCTGSSLGNLI 180
           GTPTSLGSSICEEEEEDNLSPNTFGYKLECKGEARAYRRHFLGKDHLNFYCTGSSLGNLI
Sbjct: 121 GTPTSLGSSICEEEEEDNLSPNTFGYKLECKGEARAYRRHFLGKDHLNFYCTGSSLGNLI 180

Query: 181 LSVKCEEAEGIEYLRVILRSKLKTVHERIPLAGLSKLPSVPQIAKAFCDDAVGLRFNPVL 240
           LSVKCEEAEGIEYLRVILRSKLKTVHERIPLAGLSKLPSVPQIAKAFCDDAVGLRFNPVL
Sbjct: 181 LSVKCEEAEGIEYLRVILRSKLKTVHERIPLAGLSKLPSVPQIAKAFCDDAVGLRFNPVL 240

Query: 241 YPKASQMIVSYDEHEVNNTFKFGVIYQKARQTLEEELFGNNEESPAFKEFLDLLGDTITL 300
           YPKASQMIVSYDEHEVNNTFKFGVIYQKARQTLEEELFGNNEESPAFKEFLDLLGDTITL
Sbjct: 241 YPKASQMIVSYDEHEVNNTFKFGVIYQKARQTLEEELFGNNEESPAFKEFLDLLGDTITL 300

Query: 301 QDFKGFRGGLDVTHGQTGVESVYTTFRDREIMFHVSTKLPFTDGDAQQLQRKRHIGNDIV 360
           QDFKGFRGGLDVTHGQTGVESVYTTFRDREIMFHVSTKLPFTDGDAQQLQRKRHIGNDIV
Sbjct: 301 QDFKGFRGGLDVTHGQTGVESVYTTFRDREIMFHVSTKLPFTDGDAQQLQRKRHIGNDIV 360

Query: 361 AIIFQEENTPFVPDMIASNFLHAYIVVQVETPGTETPSYKVSVTAREDVPTFGPPLPSPP 420
           AIIFQEENTPFVPDMIASNFLHAYIVVQVETPGTETPSYKVSVTAREDVPTFGPPLPSPP
Sbjct: 361 AIIFQEENTPFVPDMIASNFLHAYIVVQVETPGTETPSYKVSVTAREDVPTFGPPLPSPP 420

Query: 421 VFQKGPEFREFLLTKLTNAENACCKSDKFAKLEDRTRAALLDNLHDELHAHTQAMLGLGP 480
           VFQKGPEFREFLLTKLTNAENACCKSDKFAKLEDRTRAALLDNLHDELHAHTQAMLGLGP
Sbjct: 421 VFQKGPEFREFLLTKLTNAENACCKSDKFAKLEDRTRAALLDNLHDELHAHTQAMLGLGP 480

Query: 481 EEDKFENGGHGGFLESFKRAIRVRSHSMETMVGGQKKSHSGGIPGSLSGGISHNSMEVTK 540
           EEDKFENGGHGGFLESFKRAIRVRSHSMETMVGGQKKSHSGGIPGSLSGGISHNSMEVTK
Sbjct: 481 EEDKFENGGHGGFLESFKRAIRVRSHSMETMVGGQKKSHSGGIPGSLSGGISHNSMEVTK 540

Query: 541 TTFSPPVVAATVKNQSRSPIKRRSGLFPRLHTGSEGQGDSRARCDSTSSTPKTPDGGHSS 600
           TTFSPPVVAATVKNQSRSPIKRRSGLFPRLHTGSEGQGDSRARCDSTSSTPKTPDGGHSS
Sbjct: 541 TTFSPPVVAATVKNQSRSPIKRRSGLFPRLHTGSEGQGDSRARCDSTSSTPKTPDGGHSS 600

Query: 601 QEIKSETSSNPSSPEICPNKEKPFMKLKENGRAISRSSSSTSSVSSTAGEGEAMEEGDSG 660
           QEIKSETSSNPSSPEICPNKEKPFMKLKENGRAISRSSSSTSSVSSTAGEGEAMEEGDSG
Sbjct: 601 QEIKSETSSNPSSPEICPNKEKPFMKLKENGRAISRSSSSTSSVSSTAGEGEAMEEGDSG 660

Query: 661 GSQPSTTSPFKQEVFVYSPSPSSESPSLGAAATPIIMSRSPTDAKSRNSPRSNLKFRFDK 720
           GSQPSTTSPFKQEVFVYSPSPSSESPSLGAAATPIIMSRSPTDAKSRNSPRSNLKFRFDK
Sbjct: 661 GSQPSTTSPFKQEVFVYSPSPSSESPSLGAAATPIIMSRSPTDAKSRNSPRSNLKFRFDK 720

Query: 721 LSHASSGAGH 730
           LSHASSGAGH
Sbjct: 721 LSHASSGAGH 730


>gi|156086740 GTPase activating Rap/RanGAP domain-like 4 isoform 2
           [Homo sapiens]
          Length = 715

 Score = 1431 bits (3704), Expect = 0.0
 Identities = 715/730 (97%), Positives = 715/730 (97%), Gaps = 15/730 (2%)

Query: 1   MFGRKRSVSFGGFGWIDKTMLASLKVKKQELANSSDATLPDRPLSPPLTAPPTMKSSEFF 60
           MFGRKRSVSFGGFGWIDKTMLASLKVKKQELANSSDATLPDRPLSPPLTAPPTMKSSEFF
Sbjct: 1   MFGRKRSVSFGGFGWIDKTMLASLKVKKQELANSSDATLPDRPLSPPLTAPPTMKSSEFF 60

Query: 61  EMLEKMQGIKLEEQKPGPQKNKDDYIPYPSIDEVVEKGGPYPQVILPQFGGYWIEDPENV 120
           EMLEKMQ               DDYIPYPSIDEVVEKGGPYPQVILPQFGGYWIEDPENV
Sbjct: 61  EMLEKMQ---------------DDYIPYPSIDEVVEKGGPYPQVILPQFGGYWIEDPENV 105

Query: 121 GTPTSLGSSICEEEEEDNLSPNTFGYKLECKGEARAYRRHFLGKDHLNFYCTGSSLGNLI 180
           GTPTSLGSSICEEEEEDNLSPNTFGYKLECKGEARAYRRHFLGKDHLNFYCTGSSLGNLI
Sbjct: 106 GTPTSLGSSICEEEEEDNLSPNTFGYKLECKGEARAYRRHFLGKDHLNFYCTGSSLGNLI 165

Query: 181 LSVKCEEAEGIEYLRVILRSKLKTVHERIPLAGLSKLPSVPQIAKAFCDDAVGLRFNPVL 240
           LSVKCEEAEGIEYLRVILRSKLKTVHERIPLAGLSKLPSVPQIAKAFCDDAVGLRFNPVL
Sbjct: 166 LSVKCEEAEGIEYLRVILRSKLKTVHERIPLAGLSKLPSVPQIAKAFCDDAVGLRFNPVL 225

Query: 241 YPKASQMIVSYDEHEVNNTFKFGVIYQKARQTLEEELFGNNEESPAFKEFLDLLGDTITL 300
           YPKASQMIVSYDEHEVNNTFKFGVIYQKARQTLEEELFGNNEESPAFKEFLDLLGDTITL
Sbjct: 226 YPKASQMIVSYDEHEVNNTFKFGVIYQKARQTLEEELFGNNEESPAFKEFLDLLGDTITL 285

Query: 301 QDFKGFRGGLDVTHGQTGVESVYTTFRDREIMFHVSTKLPFTDGDAQQLQRKRHIGNDIV 360
           QDFKGFRGGLDVTHGQTGVESVYTTFRDREIMFHVSTKLPFTDGDAQQLQRKRHIGNDIV
Sbjct: 286 QDFKGFRGGLDVTHGQTGVESVYTTFRDREIMFHVSTKLPFTDGDAQQLQRKRHIGNDIV 345

Query: 361 AIIFQEENTPFVPDMIASNFLHAYIVVQVETPGTETPSYKVSVTAREDVPTFGPPLPSPP 420
           AIIFQEENTPFVPDMIASNFLHAYIVVQVETPGTETPSYKVSVTAREDVPTFGPPLPSPP
Sbjct: 346 AIIFQEENTPFVPDMIASNFLHAYIVVQVETPGTETPSYKVSVTAREDVPTFGPPLPSPP 405

Query: 421 VFQKGPEFREFLLTKLTNAENACCKSDKFAKLEDRTRAALLDNLHDELHAHTQAMLGLGP 480
           VFQKGPEFREFLLTKLTNAENACCKSDKFAKLEDRTRAALLDNLHDELHAHTQAMLGLGP
Sbjct: 406 VFQKGPEFREFLLTKLTNAENACCKSDKFAKLEDRTRAALLDNLHDELHAHTQAMLGLGP 465

Query: 481 EEDKFENGGHGGFLESFKRAIRVRSHSMETMVGGQKKSHSGGIPGSLSGGISHNSMEVTK 540
           EEDKFENGGHGGFLESFKRAIRVRSHSMETMVGGQKKSHSGGIPGSLSGGISHNSMEVTK
Sbjct: 466 EEDKFENGGHGGFLESFKRAIRVRSHSMETMVGGQKKSHSGGIPGSLSGGISHNSMEVTK 525

Query: 541 TTFSPPVVAATVKNQSRSPIKRRSGLFPRLHTGSEGQGDSRARCDSTSSTPKTPDGGHSS 600
           TTFSPPVVAATVKNQSRSPIKRRSGLFPRLHTGSEGQGDSRARCDSTSSTPKTPDGGHSS
Sbjct: 526 TTFSPPVVAATVKNQSRSPIKRRSGLFPRLHTGSEGQGDSRARCDSTSSTPKTPDGGHSS 585

Query: 601 QEIKSETSSNPSSPEICPNKEKPFMKLKENGRAISRSSSSTSSVSSTAGEGEAMEEGDSG 660
           QEIKSETSSNPSSPEICPNKEKPFMKLKENGRAISRSSSSTSSVSSTAGEGEAMEEGDSG
Sbjct: 586 QEIKSETSSNPSSPEICPNKEKPFMKLKENGRAISRSSSSTSSVSSTAGEGEAMEEGDSG 645

Query: 661 GSQPSTTSPFKQEVFVYSPSPSSESPSLGAAATPIIMSRSPTDAKSRNSPRSNLKFRFDK 720
           GSQPSTTSPFKQEVFVYSPSPSSESPSLGAAATPIIMSRSPTDAKSRNSPRSNLKFRFDK
Sbjct: 646 GSQPSTTSPFKQEVFVYSPSPSSESPSLGAAATPIIMSRSPTDAKSRNSPRSNLKFRFDK 705

Query: 721 LSHASSGAGH 730
           LSHASSGAGH
Sbjct: 706 LSHASSGAGH 715


>gi|224809578 RAP1 GTPase activating protein isoform a [Homo
           sapiens]
          Length = 727

 Score =  667 bits (1722), Expect = 0.0
 Identities = 368/716 (51%), Positives = 481/716 (67%), Gaps = 35/716 (4%)

Query: 1   MFGRKRSVSFGGFGWIDKTMLASLKVKKQELANSSDATLPDRP---LSPPLTAPPTMKSS 57
           M GRKRS +FG +G +DK+  +   V + +  N       D     L P  T     K++
Sbjct: 1   MSGRKRSFTFGAYGGVDKSFTSRRSVWRSDGQNQHFPQALDLSRVNLVPSYTPSLYPKNT 60

Query: 58  EFFEMLEKMQGIKLEEQK---PGPQKNKDDYIPYPSIDEVVEKGGPYPQVILPQFGGYWI 114
           + FEM+EKMQG +++EQ+   P P K ++DYIPYPS+ EV+ + GP+P ++LPQFGGYWI
Sbjct: 61  DLFEMIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLGREGPFPLILLPQFGGYWI 120

Query: 115 EDPENVGTPTSLGSSICEEEEEDNLSPNTFGYKLECKGEARAYRRHFLGKDHLNFYCTGS 174
           E   +          I    E + L   T   KLEC   AR YR+HFLGK+H N+Y   +
Sbjct: 121 EGTNH---------EITSIPETEPLQSPTTKVKLECNPTARIYRKHFLGKEHFNYYSLDA 171

Query: 175 SLGNLILSVKCEEAEGIEYLRVILRSKLKTVHERIPLAGLSKLPSVPQIAKAFCDDAVGL 234
           +LG+L+ S+K +     E+LR++LR+K +T H+ IP++ L++ P+V Q+AK  C+D    
Sbjct: 172 ALGHLVFSLKYDVIGDQEHLRLLLRTKCRTYHDVIPISCLTEFPNVVQMAKLVCEDVNVD 231

Query: 235 RFNPVLYPKASQMIVSYDEHEVNNTFKFGVIYQKARQTLEEELFGNNEESPAFKEFLDLL 294
           RF PVLYPKAS++IV++DEH ++N FKFGVIYQK  QT EEELF  NEESPAF EFL+ L
Sbjct: 232 RFYPVLYPKASRLIVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFL 291

Query: 295 GDTITLQDFKGFRGGLDVTHGQTGVESVYTTFRDREIMFHVSTKLPFTDGDAQQLQRKRH 354
           G  + LQDFKGFRGGLDVTHGQTG ESVY  FR++EIMFHVSTKLP+T+GDAQQLQRKRH
Sbjct: 292 GQKVKLQDFKGFRGGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRH 351

Query: 355 IGNDIVAIIFQEENTPFVPDMIASNFLHAYIVVQVETPGTETPSYKVSVTAREDVPTFGP 414
           IGNDIVA++FQ+ENTPFVPDMIASNFLHAY+VVQ E  G + P YKVSVTAR+DVP FGP
Sbjct: 352 IGNDIVAVVFQDENTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGP 411

Query: 415 PLPSPPVFQKGPEFREFLLTKLTNAENACCKSDKFAKLEDRTRAALLDNLHDELHAHTQA 474
           PLP P VF+KGPEF+EFLLTKL NAE AC K++KFAKLE+RTRAALL+ L++ELH H+Q+
Sbjct: 412 PLPDPAVFRKGPEFQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEELHIHSQS 471

Query: 475 MLGLGPEEDKFENG-GHGGFLESFKRAIRVRSHSMETMVGGQKKSHSGGIPGSLSGGISH 533
           M+GLG +EDK ENG G GGF ESFKR IR RS SM+ M    KK ++  +  S SG  + 
Sbjct: 472 MMGLGGDEDKMENGSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNT--VSTSHSGSFAP 529

Query: 534 NSMEVTKTTFSPPVVAATVKNQSRSPIKRRSGLFPRLHT---GSEGQGDSRARCDSTSST 590
           N+ ++ K      +V        +SP +++SG F    +   G E   + + + +S  + 
Sbjct: 530 NNPDLAKAAGISLIV------PGKSPTRKKSGPFGSRRSSAIGIENIQEVQEKRESPPAG 583

Query: 591 PKTPDGGHSSQEIKSETSSNPSSPEI--CPNKEKPFMKLKENGRAISRSSSSTSSVSSTA 648
            KTPD GH SQE KSE SS  SSPE+    N+ +   +  E  +  SRSSSS SS +S  
Sbjct: 584 QKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRAETAAQRAEALKDFSRSSSSASSFASVV 643

Query: 649 GEGEAMEEGDSG-GSQPSTTSPFKQEVFVYSP--SPSSESPSLGAAATPIIMSRSP 701
            E E ++  D+G  S  S+ +P K++ F+YS     S  + S G++  P   SRSP
Sbjct: 644 EETEGVDGEDTGLESVSSSGTPHKRDSFIYSTWLEDSVSTTSGGSSPGP---SRSP 696


>gi|224809582 RAP1 GTPase activating protein isoform c [Homo
           sapiens]
          Length = 663

 Score =  642 bits (1655), Expect = 0.0
 Identities = 348/652 (53%), Positives = 451/652 (69%), Gaps = 32/652 (4%)

Query: 62  MLEKMQGIKLEEQK---PGPQKNKDDYIPYPSIDEVVEKGGPYPQVILPQFGGYWIEDPE 118
           M+EKMQG +++EQ+   P P K ++DYIPYPS+ EV+ + GP+P ++LPQFGGYWIE   
Sbjct: 1   MIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLGREGPFPLILLPQFGGYWIEGTN 60

Query: 119 NVGTPTSLGSSICEEEEEDNLSPNTFGYKLECKGEARAYRRHFLGKDHLNFYCTGSSLGN 178
           +          I    E + L   T   KLEC   AR YR+HFLGK+H N+Y   ++LG+
Sbjct: 61  H---------EITSIPETEPLQSPTTKVKLECNPTARIYRKHFLGKEHFNYYSLDAALGH 111

Query: 179 LILSVKCEEAEGIEYLRVILRSKLKTVHERIPLAGLSKLPSVPQIAKAFCDDAVGLRFNP 238
           L+ S+K +     E+LR++LR+K +T H+ IP++ L++ P+V Q+AK  C+D    RF P
Sbjct: 112 LVFSLKYDVIGDQEHLRLLLRTKCRTYHDVIPISCLTEFPNVVQMAKLVCEDVNVDRFYP 171

Query: 239 VLYPKASQMIVSYDEHEVNNTFKFGVIYQKARQTLEEELFGNNEESPAFKEFLDLLGDTI 298
           VLYPKAS++IV++DEH ++N FKFGVIYQK  QT EEELF  NEESPAF EFL+ LG  +
Sbjct: 172 VLYPKASRLIVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKV 231

Query: 299 TLQDFKGFRGGLDVTHGQTGVESVYTTFRDREIMFHVSTKLPFTDGDAQQLQRKRHIGND 358
            LQDFKGFRGGLDVTHGQTG ESVY  FR++EIMFHVSTKLP+T+GDAQQLQRKRHIGND
Sbjct: 232 KLQDFKGFRGGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGND 291

Query: 359 IVAIIFQEENTPFVPDMIASNFLHAYIVVQVETPGTETPSYKVSVTAREDVPTFGPPLPS 418
           IVA++FQ+ENTPFVPDMIASNFLHAY+VVQ E  G + P YKVSVTAR+DVP FGPPLP 
Sbjct: 292 IVAVVFQDENTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLPD 351

Query: 419 PPVFQKGPEFREFLLTKLTNAENACCKSDKFAKLEDRTRAALLDNLHDELHAHTQAMLGL 478
           P VF+KGPEF+EFLLTKL NAE AC K++KFAKLE+RTRAALL+ L++ELH H+Q+M+GL
Sbjct: 352 PAVFRKGPEFQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEELHIHSQSMMGL 411

Query: 479 GPEEDKFENG-GHGGFLESFKRAIRVRSHSMETMVGGQKKSHSGGIPGSLSGGISHNSME 537
           G +EDK ENG G GGF ESFKR IR RS SM+ M    KK ++  +  S SG  + N+ +
Sbjct: 412 GGDEDKMENGSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNT--VSTSHSGSFAPNNPD 469

Query: 538 VTKTTFSPPVVAATVKNQSRSPIKRRSGLFPRLHT---GSEGQGDSRARCDSTSSTPKTP 594
           + K      +V        +SP +++SG F    +   G E   + + + +S  +  KTP
Sbjct: 470 LAKAAGISLIV------PGKSPTRKKSGPFGSRRSSAIGIENIQEVQEKRESPPAGQKTP 523

Query: 595 DGGHSSQEIKSETSSNPSSPEI--CPNKEKPFMKLKENGRAISRSSSSTSSVSSTAGEGE 652
           D GH SQE KSE SS  SSPE+    N+ +   +  E  +  SRSSSS SS +S   E E
Sbjct: 524 DSGHVSQEPKSENSSTQSSPEMPTTKNRAETAAQRAEALKDFSRSSSSASSFASVVEETE 583

Query: 653 AMEEGDSG-GSQPSTTSPFKQEVFVYSP--SPSSESPSLGAAATPIIMSRSP 701
            ++  D+G  S  S+ +P K++ F+YS     S  + S G++  P   SRSP
Sbjct: 584 GVDGEDTGLESVSSSGTPHKRDSFIYSTWLEDSVSTTSGGSSPGP---SRSP 632


>gi|224809573 RAP1 GTPase activating protein isoform b [Homo
           sapiens]
          Length = 681

 Score =  633 bits (1633), Expect = 0.0
 Identities = 342/650 (52%), Positives = 438/650 (67%), Gaps = 47/650 (7%)

Query: 62  MLEKMQGIKLEEQK---PGPQKNKDDYIPYPSIDEVVEKGGPYPQVILPQFGGYWIEDPE 118
           M+EKMQG +++EQ+   P P K ++DYIPYPS+ EV+ + GP+P ++LPQFGGYWIE   
Sbjct: 1   MIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLGREGPFPLILLPQFGGYWIEGTN 60

Query: 119 NVGTPTSLGSSICEEEEEDNLSPNTFGYKLECKGEARAYRRHFLGKDHLNFYCTGSSLGN 178
           +          I    E + L   T   KLEC   AR YR+HFLGK+H N+Y   ++LG+
Sbjct: 61  H---------EITSIPETEPLQSPTTKVKLECNPTARIYRKHFLGKEHFNYYSLDAALGH 111

Query: 179 LILSVKCEEAEGIEYLRVILRSKLKTVHERIPLAGLSKLPSVPQIAKAFCDDAVGLRFNP 238
           L+ S+K +     E+LR++LR+K +T H+ IP++ L++ P+V Q+AK  C+D    RF P
Sbjct: 112 LVFSLKYDVIGDQEHLRLLLRTKCRTYHDVIPISCLTEFPNVVQMAKLVCEDVNVDRFYP 171

Query: 239 VLYPKASQMIVSYDEHEVNNTFKFGVIYQKARQTLEEELFGNNEESPAFKEFLDLLGDTI 298
           VLYPKAS++IV++DEH ++N FKFGVIYQK  QT EEELF  NEESPAF EFL+ LG  +
Sbjct: 172 VLYPKASRLIVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKV 231

Query: 299 TLQDFKGFRGGLDVTHGQTGVESVYTTFRDREIMFHVSTKLPFTDGDAQQLQRKRHIGND 358
            LQDFKGFRGGLDVTHGQTG ESVY  FR++EIMFHVSTKLP+T+GDAQQLQRKRHIGND
Sbjct: 232 KLQDFKGFRGGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGND 291

Query: 359 IVAIIFQEENTPFVPDMIASNFLHAYIVVQVETPGTETPSYKVSVTAREDVPTFGPPLPS 418
           IVA++FQ+ENTPFVPDMIASNFLHAY+VVQ E  G + P YKVSVTAR+DVP FGPPLP 
Sbjct: 292 IVAVVFQDENTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLPD 351

Query: 419 PPVFQKGPEFREFLLTKLTNAENACCKSDKFAKLEDRTRAALLDNLHDELHAHTQAMLGL 478
           P VF+KGPEF+EFLLTKL NAE AC K++KFAKLE+RTRAALL+ L++ELH H+Q+M+GL
Sbjct: 352 PAVFRKGPEFQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEELHIHSQSMMGL 411

Query: 479 GPEEDKFENG-GHGGFLESFKRAIRVRSHSMETMVGGQKK------SHSGG--------- 522
           G +EDK ENG G GGF ESFKR IR RS SM+ M    KK      SHSG          
Sbjct: 412 GGDEDKMENGSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNTVSTSHSGSFAPNNPDLA 471

Query: 523 --------IPGSLSGGISHNSMEVTKTTFSPPVVAATVKNQSRSPIKRRSGLFPRLHT-- 572
                   IPG  +         +   T    ++        +SP +++SG F    +  
Sbjct: 472 KAAGISLLIPGKSASRFGRRGSAIGIGTVEESLIV-----PGKSPTRKKSGPFGSRRSSA 526

Query: 573 -GSEGQGDSRARCDSTSSTPKTPDGGHSSQEIKSETSSNPSSPEI--CPNKEKPFMKLKE 629
            G E   + + + +S  +  KTPD GH SQE KSE SS  SSPE+    N+ +   +  E
Sbjct: 527 IGIENIQEVQEKRESPPAGQKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRAETAAQRAE 586

Query: 630 NGRAISRSSSSTSSVSSTAGEGEAMEEGDSG-GSQPSTTSPFKQEVFVYS 678
             +  SRSSSS SS +S   E E ++  D+G  S  S+ +P K++ F+YS
Sbjct: 587 ALKDFSRSSSSASSFASVVEETEGVDGEDTGLESVSSSGTPHKRDSFIYS 636


>gi|71143119 signal-induced proliferation-associated 1 like 3 [Homo
           sapiens]
          Length = 1781

 Score =  234 bits (598), Expect = 2e-61
 Identities = 144/389 (37%), Positives = 210/389 (53%), Gaps = 27/389 (6%)

Query: 107 PQFGGYWIEDPENVGTPTSLGSSICE---EEEEDNLSPNTFGYKLECKGEARAYRRHFLG 163
           P  G   + +P      T+   S+ E   E++     P  +  +    G AR Y+ +F+G
Sbjct: 452 PSSGEGHLAEPALSAYRTNASISVLEVPKEQQRTQSRPRQYSIEHVDLG-ARYYQDYFVG 510

Query: 164 KDHLNFYCTGSSLGNLILSVKCEEAE-----GIEY-LRVILRSKL------KTVHERIPL 211
           K+H N++     LG + +S+K E+ E     G +Y  R+I R++         + +  P 
Sbjct: 511 KEHANYFGVDEKLGPVAVSIKREKLEDHKEHGPQYQYRIIFRTRELITLRGSILEDATPT 570

Query: 212 A-------GLSKLPSVPQIAKAFCDDAVGLRFNPVLYPKASQMIVSYDEHEVNNTFKFGV 264
           A       GL    ++  +        + L  N    PK ++ ++  DE  +    K G+
Sbjct: 571 ATKHGTGRGLPLKDALEYVIPELNIHCLRLALNT---PKVTEQLLKLDEQGLCRKHKVGI 627

Query: 265 IYQKARQTLEEELFGNNEESPAFKEFLDLLGDTITLQDFKGFRGGLDVTHGQTGVESVYT 324
           +Y KA Q+ EEE++ N E  PAF+EFL L+G+ + L+ F  +   LDV    TG  S+YT
Sbjct: 628 LYCKAGQSSEEEMYNNEEAGPAFEEFLSLIGEKVCLKGFTKYAAQLDVKTDSTGTHSLYT 687

Query: 325 TFRDREIMFHVSTKLPFTDGDAQQLQRKRHIGNDIVAIIFQEENT-PFVPDMIASNFLHA 383
            ++D EIMFHVST LP+T  + QQL RKRHIGNDIV IIFQE    PF P  I S+F H 
Sbjct: 688 MYQDYEIMFHVSTLLPYTPNNRQQLLRKRHIGNDIVTIIFQEPGALPFTPKNIRSHFQHV 747

Query: 384 YIVVQVETPGTETPSYKVSVTAREDVPTFGPPLPSPPVFQKGPEFREFLLTKLTNAENAC 443
           +I+V+V  P T+   Y ++VT  +D P FGPP+PS   F+K   FR+FLL K+ NAENA 
Sbjct: 748 FIIVRVHNPCTDNVCYSMAVTRSKDAPPFGPPIPSGTTFRKSDVFRDFLLAKVINAENAA 807

Query: 444 CKSDKFAKLEDRTRAALLDNLHDELHAHT 472
            KSDKF  +  RTR   L +L +   ++T
Sbjct: 808 HKSDKFHTMATRTRQEYLKDLAENCVSNT 836



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 60/249 (24%), Positives = 93/249 (37%), Gaps = 25/249 (10%)

Query: 485  FENGG-HGGFLESFKRAIRVRSHSMETMVGGQKKSHSGGIPGSLSGGISHNSMEVTKTTF 543
            FE+G    G+ E++           E++  G +  +    P   SG  SHNS+  +K  +
Sbjct: 1041 FEDGTPRRGWPETYDMNTSEPKTEQESITPGGRPPYRSNAPWQWSGPASHNSLPASK--W 1098

Query: 544  SPPVVAATVKNQSRSPIKRRSGLFPRLHTGSEGQGDSRARCDSTSSTPKT--PDGGHSSQ 601
            + P      ++ SR P+K+       +    E Q     R  S   TP T  P G     
Sbjct: 1099 ATPTTPGHAQSLSR-PLKQTP-----IVPFRESQPLHSKRPVSFPETPYTVSPAGADRVP 1152

Query: 602  EIK--SETSSNPSSPEICPNKEKPFMKLKENGRAISRSSSSTSSVSSTAGEGEAMEEGDS 659
              +  S + S P S      K  P        R  +      S     + +G +  +  S
Sbjct: 1153 PYRQPSGSFSTPGSATYVRYKPSP-------ERYTAAPHPLLSLDPHFSHDGTSSGDSSS 1205

Query: 660  GG--SQPSTTSPFKQEVFVYSPSPSSESPSLGAAATPIIMSRSPTDAKSRNSPRSNLKFR 717
            GG  SQ ST    K E   + P+ +  S   G++        S  DA  ++SP  + K  
Sbjct: 1206 GGLTSQESTMERQKPEPLWHVPAQARLSAIAGSSGN---KHPSRQDAAGKDSPNRHSKGE 1262

Query: 718  FDKLSHASS 726
                SH+SS
Sbjct: 1263 PQYSSHSSS 1271


>gi|7662126 signal-induced proliferation-associated 1 like 1 [Homo
           sapiens]
          Length = 1804

 Score =  231 bits (589), Expect = 2e-60
 Identities = 134/335 (40%), Positives = 190/335 (56%), Gaps = 31/335 (9%)

Query: 157 YRRHFLGKDHLNFYCTGSSLGNLILSVKCEEAE-----GIEY-LRVILRSKLKTVHERIP 210
           YR+ F  K+H N++    +LG + +S++ E+ +     G  Y  R+I R+      E + 
Sbjct: 492 YRKFFYQKEHWNYFGADENLGPVAVSIRREKPDEMKENGSPYNYRIIFRTS-----ELMT 546

Query: 211 LAGLSKLPSVPQIAKAFCDDAVGLRFNPVLY-----------------PKASQMIVSYDE 253
           L G     ++P  AK     A GL    VL                  PK ++ ++  DE
Sbjct: 547 LRGSVLEDAIPSTAKH--STARGLPLKEVLEHVVPELNVQCLRLAFNTPKVTEQLMKLDE 604

Query: 254 HEVNNTFKFGVIYQKARQTLEEELFGNNEESPAFKEFLDLLGDTITLQDFKGFRGGLDVT 313
             +N   K G++Y KA Q+ EEE++ N    PAF+EFL LLG+ + L+ F+ +R  LD  
Sbjct: 605 QGLNYQQKVGIMYCKAGQSTEEEMYNNESAGPAFEEFLQLLGERVRLKGFEKYRAQLDTK 664

Query: 314 HGQTGVESVYTTFRDREIMFHVSTKLPFTDGDAQQLQRKRHIGNDIVAIIFQEENT-PFV 372
              TG  S+YTT++D EIMFHVST LP+T  + QQL RKRHIGNDIV I+FQE    PF 
Sbjct: 665 TDSTGTHSLYTTYKDYEIMFHVSTMLPYTPNNKQQLLRKRHIGNDIVTIVFQEPGAQPFS 724

Query: 373 PDMIASNFLHAYIVVQVETPGTETPSYKVSVTAREDVPTFGPPLPSPPVFQKGPEFREFL 432
           P  I S+F H +++V+V  P +++  Y V+VT   DVP+FGPP+P    F K   FR+FL
Sbjct: 725 PKNIRSHFQHVFVIVRVHNPCSDSVCYSVAVTRSRDVPSFGPPIPKGVTFPKSNVFRDFL 784

Query: 433 LTKLTNAENACCKSDKFAKLEDRTRAALLDNLHDE 467
           L K+ NAENA  KS+KF  +  RTR   L +L ++
Sbjct: 785 LAKVINAENAAHKSEKFRAMATRTRQEYLKDLAEK 819


>gi|112421013 signal-induced proliferation-associated 1 like 2 [Homo
           sapiens]
          Length = 1722

 Score =  230 bits (586), Expect = 4e-60
 Identities = 135/333 (40%), Positives = 184/333 (55%), Gaps = 32/333 (9%)

Query: 157 YRRHFLGKDHLNFYCTGSSLGNLILSVKCE------EAEGIEY-LRVILRSKLKTVHERI 209
           YR+ F GK+H N++    +LG + +S++ E      E EG ++  RV  R+      E  
Sbjct: 487 YRKFFYGKEHQNYFGIDENLGPVAVSIRREKVEDAKEKEGSQFNYRVAFRTS-----ELT 541

Query: 210 PLAGLSKLPSVPQIAKAFCDDAVGLRFNPVLY-----------------PKASQMIVSYD 252
            L G     ++P  A+     A GL    VL                  PK S+ ++  D
Sbjct: 542 TLRGAILEDAIPSTARH--GTARGLPLKEVLEYVIPELSIQCLRQASNSPKVSEQLLKLD 599

Query: 253 EHEVNNTFKFGVIYQKARQTLEEELFGNNEESPAFKEFLDLLGDTITLQDFKGFRGGLDV 312
           E  ++   K G++Y KA Q+ EEE++ N    PAF+EFLDLLG  + L+ F  +R  LD 
Sbjct: 600 EQGLSFQHKIGILYCKAGQSTEEEMYNNETAGPAFEEFLDLLGQRVRLKGFSKYRAQLDN 659

Query: 313 THGQTGVESVYTTFRDREIMFHVSTKLPFTDGDAQQLQRKRHIGNDIVAIIFQEENT-PF 371
               TG  S+YTT++D E+MFHVST LP+   + QQL RKRHIGNDIV I+FQE    PF
Sbjct: 660 KTDSTGTHSLYTTYKDYELMFHVSTLLPYMPNNRQQLLRKRHIGNDIVTIVFQEPGALPF 719

Query: 372 VPDMIASNFLHAYIVVQVETPGTETPSYKVSVTAREDVPTFGPPLPSPPVFQKGPEFREF 431
            P  I S+F H +++V+V  P TE   Y V V+  +DVP FGPP+P    F K   FR+F
Sbjct: 720 TPKSIRSHFQHVFVIVKVHNPCTENVCYSVGVSRSKDVPPFGPPIPKGVTFPKSAVFRDF 779

Query: 432 LLTKLTNAENACCKSDKFAKLEDRTRAALLDNL 464
           LL K+ NAENA  KS+KF  +  RTR   L +L
Sbjct: 780 LLAKVINAENAAHKSEKFRAMATRTRQEYLKDL 812


>gi|206725526 signal-induced proliferation-associated protein 1
           [Homo sapiens]
          Length = 1042

 Score =  222 bits (565), Expect = 1e-57
 Identities = 139/353 (39%), Positives = 195/353 (55%), Gaps = 25/353 (7%)

Query: 129 SICEEEEEDNLSPNTFGYKLECKG-EARAYRRHFLGKDHLNFYCTGSSLGNLILSVKCEE 187
           SI EE +       T  Y LE     A  YR++F GK+H NF+    SLG + +S++ EE
Sbjct: 195 SILEEPQN-----RTSAYSLEHADLGAGYYRKYFYGKEHQNFFGMDESLGPVAVSLRREE 249

Query: 188 AEG-----IEYLRVILRS-KLKTVHERI--------PLAGLSKLPSVPQIAKAFCDDAVG 233
            EG     +   RVI+R+ +L+T+   I        P  GLS    +  +A       + 
Sbjct: 250 KEGSGGGTLHSYRVIVRTTQLRTLRGTISEDALPPGPPRGLSPRKLLEHVAPQLSPSCLR 309

Query: 234 LRFNPVLYPKASQMIVSYDEHEVNNTFKFGVIYQKARQTLEEELFGNNEESPAFKEFLDL 293
           L       PK  + +++ DE  ++   K G++Y +A Q  EEE++ N E  PAF +FL L
Sbjct: 310 LGSAS---PKVPRTLLTLDEQVLSFQRKVGILYCRAGQGSEEEMYNNQEAGPAFMQFLTL 366

Query: 294 LGDTITLQDFKGFRGGLDVTHGQTGVESVYTTFRDREIMFHVSTKLPFTDGDAQQLQRKR 353
           LGD + L+ F+ +R  LD     TG  S+YTT++D EIMFHVST LP+T  + QQL RKR
Sbjct: 367 LGDVVRLKGFESYRAQLDTKTDSTGTHSLYTTYQDHEIMFHVSTMLPYTPNNQQQLLRKR 426

Query: 354 HIGNDIVAIIFQEENT-PFVPDMIASNFLHAYIVVQVETPGTETPSYKVSVTAREDVPTF 412
           HIGNDIV I+FQE  + PF P  I S+F H ++VV+  TP T   +Y+V+V+  +D P F
Sbjct: 427 HIGNDIVTIVFQEPGSKPFCPTTIRSHFQHVFLVVRAHTPCTPHTTYRVAVSRTQDTPAF 486

Query: 413 GPPLPS-PPVFQKGPEFREFLLTKLTNAENACCKSDKFAKLEDRTRAALLDNL 464
           GP LP+    F    +FR FLL K  N E A   + +F  +  RTR   L +L
Sbjct: 487 GPALPAGGGPFAANADFRAFLLAKALNGEQAAGHARQFHAMATRTRQQYLQDL 539


>gi|206725523 signal-induced proliferation-associated protein 1
           [Homo sapiens]
          Length = 1042

 Score =  222 bits (565), Expect = 1e-57
 Identities = 139/353 (39%), Positives = 195/353 (55%), Gaps = 25/353 (7%)

Query: 129 SICEEEEEDNLSPNTFGYKLECKG-EARAYRRHFLGKDHLNFYCTGSSLGNLILSVKCEE 187
           SI EE +       T  Y LE     A  YR++F GK+H NF+    SLG + +S++ EE
Sbjct: 195 SILEEPQN-----RTSAYSLEHADLGAGYYRKYFYGKEHQNFFGMDESLGPVAVSLRREE 249

Query: 188 AEG-----IEYLRVILRS-KLKTVHERI--------PLAGLSKLPSVPQIAKAFCDDAVG 233
            EG     +   RVI+R+ +L+T+   I        P  GLS    +  +A       + 
Sbjct: 250 KEGSGGGTLHSYRVIVRTTQLRTLRGTISEDALPPGPPRGLSPRKLLEHVAPQLSPSCLR 309

Query: 234 LRFNPVLYPKASQMIVSYDEHEVNNTFKFGVIYQKARQTLEEELFGNNEESPAFKEFLDL 293
           L       PK  + +++ DE  ++   K G++Y +A Q  EEE++ N E  PAF +FL L
Sbjct: 310 LGSAS---PKVPRTLLTLDEQVLSFQRKVGILYCRAGQGSEEEMYNNQEAGPAFMQFLTL 366

Query: 294 LGDTITLQDFKGFRGGLDVTHGQTGVESVYTTFRDREIMFHVSTKLPFTDGDAQQLQRKR 353
           LGD + L+ F+ +R  LD     TG  S+YTT++D EIMFHVST LP+T  + QQL RKR
Sbjct: 367 LGDVVRLKGFESYRAQLDTKTDSTGTHSLYTTYQDHEIMFHVSTMLPYTPNNQQQLLRKR 426

Query: 354 HIGNDIVAIIFQEENT-PFVPDMIASNFLHAYIVVQVETPGTETPSYKVSVTAREDVPTF 412
           HIGNDIV I+FQE  + PF P  I S+F H ++VV+  TP T   +Y+V+V+  +D P F
Sbjct: 427 HIGNDIVTIVFQEPGSKPFCPTTIRSHFQHVFLVVRAHTPCTPHTTYRVAVSRTQDTPAF 486

Query: 413 GPPLPS-PPVFQKGPEFREFLLTKLTNAENACCKSDKFAKLEDRTRAALLDNL 464
           GP LP+    F    +FR FLL K  N E A   + +F  +  RTR   L +L
Sbjct: 487 GPALPAGGGPFAANADFRAFLLAKALNGEQAAGHARQFHAMATRTRQQYLQDL 539


>gi|207448705 GTPase activating Rap/RanGAP domain-like 3 [Homo
           sapiens]
          Length = 1013

 Score =  222 bits (565), Expect = 1e-57
 Identities = 128/319 (40%), Positives = 186/319 (58%), Gaps = 9/319 (2%)

Query: 155 RAYRRHFLGKDHLNFYCTGSSLGNLILSVKCEEAEG--IEYLRVILRSKLKTVHERIPLA 212
           R Y ++FLG+ H N+    +      LSV   +     +   R IL  K  T    +P +
Sbjct: 97  RWYFKYFLGQVHQNYIGNDAEKSPFFLSVTLSDQNNQRVPQYRAILWRKTGTQKICLPYS 156

Query: 213 GLSKLPSVPQIAKAFCDDAVGLRFNPVLYPKASQMIVSYDEHEVNNTFKFGVIYQKARQT 272
               L SV  I  A   D        + +P+  + ++  +E E +  FKFGV++ K  Q 
Sbjct: 157 PTKTL-SVKSILSAMNLDKFEKGPREIFHPEIQKDLLVLEEQEGSVNFKFGVLFAKDGQL 215

Query: 273 LEEELFGNNEESPAFKEFLDLLGDTITLQDFKGFRGGLDVTHGQTGVESVYTTFRDREIM 332
            ++E+F N   S  F++FL+LLGDTITL+ + G+RGGLD  +  TG+ SVYT ++  EIM
Sbjct: 216 TDDEMFSNEIGSEPFQKFLNLLGDTITLKGWTGYRGGLDTKNDTTGIHSVYTVYQGHEIM 275

Query: 333 FHVSTKLPFTDGDAQQLQRKRHIGNDIVAIIFQ--EENTP-FVPDMIASNFLHAYIVVQV 389
           FHVST LP++  + QQ++RKRHIGNDIV I+FQ  EE++P F P MI S+F H + +V+ 
Sbjct: 276 FHVSTMLPYSKENKQQVERKRHIGNDIVTIVFQEGEESSPAFKPSMIRSHFTHIFALVRY 335

Query: 390 ETPGTETPSYKVSVTAREDVPTFGPPLPSPPVFQKGPEFREFLLTKLTNAENACCKSDKF 449
                +  +Y++ + + E VP FGPPLP+PPVF    EFR+FLL KL N E A  ++  F
Sbjct: 336 ---NQQNDNYRLKIFSEESVPLFGPPLPTPPVFTDHQEFRDFLLVKLINGEKATLETPTF 392

Query: 450 AKLEDRTRAALLDNLHDEL 468
           A+   RT   L+ +LH +L
Sbjct: 393 AQKRRRTLDMLIRSLHQDL 411


>gi|118600961 akt substrate AS250 [Homo sapiens]
          Length = 1873

 Score = 77.0 bits (188), Expect = 6e-14
 Identities = 49/172 (28%), Positives = 85/172 (49%), Gaps = 6/172 (3%)

Query: 243  KASQMIVSYDEHEVNNTFKFGVIYQKARQTLEEELFGNNEESPAFKEFLDLLGDTITLQD 302
            K  + + + D  +   T K  V Y    Q  +  +  N   S A+++F+  LG  + L  
Sbjct: 1630 KLLRELKNLDSRQCRETHKIAVFYIAEGQEDKCSILSNERGSQAYEDFVAGLGWEVDLST 1689

Query: 303  FKGFRGGLDVTHGQTGVESVYTTFRDREIMFHVSTKLPFTDGDAQQLQRKRHIGNDIVAI 362
              GF GGL   +G TG  + Y      E++FHVST++P +D D    ++ RH+GND V I
Sbjct: 1690 HCGFMGGLQ-RNGSTGQTAPYYATSTVEVIFHVSTRMP-SDSDDSLTKKLRHLGNDEVHI 1747

Query: 363  IFQEENTPFVPDMIASNFLHAYIVVQVETPGTETPSYKVSVTAREDVPTFGP 414
            ++ E +  +   +I + F    I++       +   + +++T + +VP FGP
Sbjct: 1748 VWSEHSRDYRRGIIPTAFGDVSIIIY----PMKNHMFFIAITKKPEVPFFGP 1795



 Score = 32.7 bits (73), Expect = 1.2
 Identities = 40/146 (27%), Positives = 58/146 (39%), Gaps = 16/146 (10%)

Query: 576 GQGDSRARCDSTSSTPKTPDGGHSSQEIKSETSSNPSSPEICPNKE-KPFMKLKENGRAI 634
           GQ     R  STS  P+ P    SSQ  K+E + N SS E  P +E K  +K +  G  I
Sbjct: 756 GQQQQVLRSSSTSDIPE-PLCSDSSQGQKAENTQNSSSSEPQPIQENKGHVKREHEGITI 814

Query: 635 --SRSSSST-----SSVSSTAGEGEAMEEGDSGGSQPSTTSPFKQEVFVYSPSPSSESPS 687
              RSSS         +  T G+    ++ +S  S  +     + E+ +       E P 
Sbjct: 815 LVRRSSSPAELDLKDDLQQTQGKCRERQKSESTNSDTTLGCTNEAELSMGPWQTCEEDPE 874

Query: 688 LGAAATPII-------MSRSPTDAKS 706
           L      +        +  SPTDA +
Sbjct: 875 LNTPTDVVADADARHWLQLSPTDASN 900


>gi|51230412 GTPase activating Rap/RanGAP domain-like 1 isoform 2
            [Homo sapiens]
          Length = 2083

 Score = 75.5 bits (184), Expect = 2e-13
 Identities = 47/163 (28%), Positives = 79/163 (48%), Gaps = 6/163 (3%)

Query: 252  DEHEVNNTFKFGVIYQKARQTLEEELFGNNEESPAFKEFLDLLGDTITLQDFKGFRGGLD 311
            D  +   T K  V Y    Q  +  +  N   S A+++F+  LG  + L +  GF GGL 
Sbjct: 1800 DSRQCRETHKIAVFYVAEGQEDKHSILTNTGGSQAYEDFVAGLGWEVNLTNHCGFMGGLQ 1859

Query: 312  VTHGQTGVESVYTTFRDREIMFHVSTKLPFTDGDAQQLQRKRHIGNDIVAIIFQEENTPF 371
              +  TG+ + Y      E++FHVST++P +D D    ++ RH+GND V I++ E    +
Sbjct: 1860 -KNKSTGLTTPYFATSTVEVIFHVSTRMP-SDSDDSLTKKLRHLGNDEVHIVWSEHTRDY 1917

Query: 372  VPDMIASNFLHAYIVVQVETPGTETPSYKVSVTAREDVPTFGP 414
               +I + F    IV+       +   + + +  + +VP FGP
Sbjct: 1918 RRGIIPTEFGDVLIVIY----PMKNHMFSIQIMKKPEVPFFGP 1956


>gi|51226124 GTPase activating Rap/RanGAP domain-like 1 isoform 1
            [Homo sapiens]
          Length = 2036

 Score = 75.5 bits (184), Expect = 2e-13
 Identities = 47/163 (28%), Positives = 79/163 (48%), Gaps = 6/163 (3%)

Query: 252  DEHEVNNTFKFGVIYQKARQTLEEELFGNNEESPAFKEFLDLLGDTITLQDFKGFRGGLD 311
            D  +   T K  V Y    Q  +  +  N   S A+++F+  LG  + L +  GF GGL 
Sbjct: 1800 DSRQCRETHKIAVFYVAEGQEDKHSILTNTGGSQAYEDFVAGLGWEVNLTNHCGFMGGLQ 1859

Query: 312  VTHGQTGVESVYTTFRDREIMFHVSTKLPFTDGDAQQLQRKRHIGNDIVAIIFQEENTPF 371
              +  TG+ + Y      E++FHVST++P +D D    ++ RH+GND V I++ E    +
Sbjct: 1860 -KNKSTGLTTPYFATSTVEVIFHVSTRMP-SDSDDSLTKKLRHLGNDEVHIVWSEHTRDY 1917

Query: 372  VPDMIASNFLHAYIVVQVETPGTETPSYKVSVTAREDVPTFGP 414
               +I + F    IV+       +   + + +  + +VP FGP
Sbjct: 1918 RRGIIPTEFGDVLIVIY----PMKNHMFSIQIMKKPEVPFFGP 1956


>gi|116256350 tuberous sclerosis 2 isoform 4 [Homo sapiens]
          Length = 1740

 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 53/165 (32%), Positives = 77/165 (46%), Gaps = 23/165 (13%)

Query: 238  PVLYPKASQ----------MIVSYDEHEVNNTFKFGVIYQKARQTLEE-ELFGNNEESPA 286
            P+L P  SQ           I SYD H      K  V+Y    Q+  E  +  N   S  
Sbjct: 1450 PILLPNESQSFERSVQLLDQIPSYDTH------KIAVLYVGEGQSNSELAILSNEHGSYR 1503

Query: 287  FKEFLDLLGDTITLQDF---KGFRGGLDVTHGQTGVESVYTTFRD-REIMFHVSTKLPFT 342
            + EFL  LG  I L+D    K + GGLDV  G+ G +  Y    D  + +FH++T +P  
Sbjct: 1504 YTEFLTGLGRLIELKDCQPDKVYLGGLDVC-GEDG-QFTYCWHDDIMQAVFHIATLMPTK 1561

Query: 343  DGDAQQLQRKRHIGNDIVAIIFQEENTPFVPDMIASNFLHAYIVV 387
            D D  +  +KRH+GND V+I++ +    F    I   F   +++V
Sbjct: 1562 DVDKHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIV 1606


>gi|116256352 tuberous sclerosis 2 isoform 1 [Homo sapiens]
          Length = 1807

 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 53/165 (32%), Positives = 77/165 (46%), Gaps = 23/165 (13%)

Query: 238  PVLYPKASQ----------MIVSYDEHEVNNTFKFGVIYQKARQTLEE-ELFGNNEESPA 286
            P+L P  SQ           I SYD H      K  V+Y    Q+  E  +  N   S  
Sbjct: 1517 PILLPNESQSFERSVQLLDQIPSYDTH------KIAVLYVGEGQSNSELAILSNEHGSYR 1570

Query: 287  FKEFLDLLGDTITLQDF---KGFRGGLDVTHGQTGVESVYTTFRD-REIMFHVSTKLPFT 342
            + EFL  LG  I L+D    K + GGLDV  G+ G +  Y    D  + +FH++T +P  
Sbjct: 1571 YTEFLTGLGRLIELKDCQPDKVYLGGLDVC-GEDG-QFTYCWHDDIMQAVFHIATLMPTK 1628

Query: 343  DGDAQQLQRKRHIGNDIVAIIFQEENTPFVPDMIASNFLHAYIVV 387
            D D  +  +KRH+GND V+I++ +    F    I   F   +++V
Sbjct: 1629 DVDKHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIV 1673


>gi|167412124 tuberous sclerosis 2 isoform 5 [Homo sapiens]
          Length = 1784

 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 53/165 (32%), Positives = 77/165 (46%), Gaps = 23/165 (13%)

Query: 238  PVLYPKASQ----------MIVSYDEHEVNNTFKFGVIYQKARQTLEE-ELFGNNEESPA 286
            P+L P  SQ           I SYD H      K  V+Y    Q+  E  +  N   S  
Sbjct: 1494 PILLPNESQSFERSVQLLDQIPSYDTH------KIAVLYVGEGQSNSELAILSNEHGSYR 1547

Query: 287  FKEFLDLLGDTITLQDF---KGFRGGLDVTHGQTGVESVYTTFRD-REIMFHVSTKLPFT 342
            + EFL  LG  I L+D    K + GGLDV  G+ G +  Y    D  + +FH++T +P  
Sbjct: 1548 YTEFLTGLGRLIELKDCQPDKVYLGGLDVC-GEDG-QFTYCWHDDIMQAVFHIATLMPTK 1605

Query: 343  DGDAQQLQRKRHIGNDIVAIIFQEENTPFVPDMIASNFLHAYIVV 387
            D D  +  +KRH+GND V+I++ +    F    I   F   +++V
Sbjct: 1606 DVDKHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIV 1650


>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
          Length = 2968

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 47/157 (29%), Positives = 69/157 (43%), Gaps = 16/157 (10%)

Query: 588  SSTPKTP----DGGHSSQE----IKSETSSNPSSPEICPNKEKPFMKLKENGRAISRSSS 639
            SS PK P      G  +QE    +  E S NP SP+    ++    + + +  + S SSS
Sbjct: 2510 SSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSS 2569

Query: 640  STSSVSSTAGEGEAMEEGD--------SGGSQPSTTSPFKQEVFVYSPSPSSESPSLGAA 691
            S+SS SS+  E E  EEGD        +GG   S  S         S S SS S S  ++
Sbjct: 2570 SSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSS 2629

Query: 692  ATPIIMSRSPTDAKSRNSPRSNLKFRFDKLSHASSGA 728
            ++    S S + + S +S  S+        S +SS +
Sbjct: 2630 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2666



 Score = 40.0 bits (92), Expect = 0.008
 Identities = 39/166 (23%), Positives = 63/166 (37%), Gaps = 30/166 (18%)

Query: 572  TGSEGQGDSRARCDSTSSTPKTPDGGHSSQEIKSETSSNPSSPEICPNKEKPFMKLKENG 631
            TG      + +R  S +S+  +     SS    S +SS+ SS     +          + 
Sbjct: 2597 TGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2656

Query: 632  RAISRSSSSTSSVSSTAGEGEAMEEGD-----------------------SGGSQPSTTS 668
             + S SSSS+SS SST  E  +    D                       +G ++PS  S
Sbjct: 2657 SSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHS 2716

Query: 669  PFKQEVFVYSPSPSSESPSLGAAATPIIMSRSPTDAKSRNSPRSNL 714
            P K+     +P+P  ++P      T  +  ++   AKSR   R  +
Sbjct: 2717 PGKK-----TPAPQPQAPP--PQPTQPLQPKAQAGAKSRPKKREGV 2755


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 52/214 (24%), Positives = 74/214 (34%), Gaps = 13/214 (6%)

Query: 510  TMVGGQKKSHSGGIPGSLSGGISHNSMEVTKTTFSP--PVVAATVKNQSRSPIKRRSGLF 567
            T V G +   SG +  + S    HN M        P   V        ++ P    + L 
Sbjct: 2467 TPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQP-SALAALQ 2525

Query: 568  PRLHTGSEGQGDSRARCDSTSSTPKTPDGGHSSQEIKSETSSNPSSPEIC----PNKEKP 623
            P     S     S +   S+SS+  +      S    SE SS P  PE+     P+    
Sbjct: 2526 PAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPA 2585

Query: 624  FMKLKENGR------AISRSSSSTSSVSSTAGEGEAMEEGDSGGSQPSTTSPFKQEVFVY 677
              +    GR      A  +  SS+SS SS++    +     S  S  S++S         
Sbjct: 2586 PKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2645

Query: 678  SPSPSSESPSLGAAATPIIMSRSPTDAKSRNSPR 711
            S SPS   P   A   P    + P   +   SPR
Sbjct: 2646 SSSPSPAKPGPQALPKPASPKKPPPGERRSRSPR 2679



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 53/239 (22%), Positives = 88/239 (36%), Gaps = 22/239 (9%)

Query: 490 HGGFLESFKRAIRVRSHSMETMVGGQKKSHSGGIPGSLSGGISHNSMEVTKTTFSPPVVA 549
           H    ES KR  R  +   +     +K+  S     +     +H S      + S    +
Sbjct: 218 HRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRS 277

Query: 550 ATVKNQSRSPIKRRSGLFPRLHTGSEGQGDSRARCDSTSST--PKTPDGGHSSQEIKSET 607
            +    +++     +G  P   +G  G+GD+      T+ST  P +P+            
Sbjct: 278 RSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPE----------TA 327

Query: 608 SSNPSSPEICPNKEKPFMKLKENGRAISRSSSSTSSVSSTAGEGEAMEEGDSGGSQPSTT 667
           +  PSSP    +K+K          +  RSS+     + T      + E   G  QP  T
Sbjct: 328 TKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTP----LLAERHGGSPQPLAT 383

Query: 668 SPFKQEVFVYSPSPSSESPSLGAAATPIIMSRSPTDAKSRNSPRSNLKFRFDKLSHASS 726
           +P  QE      +P SE+      + P    + P  + S +SP S    +  +  HASS
Sbjct: 384 TPLSQE----PVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSR--HASS 436



 Score = 40.0 bits (92), Expect = 0.008
 Identities = 49/204 (24%), Positives = 83/204 (40%), Gaps = 36/204 (17%)

Query: 532  SHNSMEVTKTTFSPPVVAATVKNQSRSPIKRRSGLFPRLHTGSEGQGDSRARC----DST 587
            S +S E+     + P   +   +   S  K R+ L  R  +GS  + DS++R       +
Sbjct: 1539 SGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRS 1598

Query: 588  SSTPKTPDGGHSSQEIKSETSSNPSSPEICPNKEKPFMKLKENGRAISRSSSSTSSVSST 647
             S+P+  D   ++   +S + S+P      P             RA+ R S S    SS+
Sbjct: 1599 GSSPEVKDKPRAAPRAQSGSDSSPEPKAPAP-------------RALPRRSRSG---SSS 1642

Query: 648  AGEGEAMEEGDSGGSQPSTTSPFKQEVFVYSPSPSSESPSLGAAATPIIMSRS---PTDA 704
             G G + E     GS  + +SP           P S +   G+ ++P   ++S   P   
Sbjct: 1643 KGRGPSPE-----GSSSTESSP--------EHPPKSRTARRGSRSSPEPKTKSRTPPRRR 1689

Query: 705  KSRNSPRSNLKFRFDKLSHASSGA 728
             SR+SP    K R  + S ++S +
Sbjct: 1690 SSRSSPELTRKARLSRRSRSASSS 1713



 Score = 38.9 bits (89), Expect = 0.017
 Identities = 41/164 (25%), Positives = 65/164 (39%), Gaps = 24/164 (14%)

Query: 553 KNQSRSPIKRRSGLFPRLHTGSEGQGDSRARCDSTSSTPKTPDGGHSSQEIKSETSSNPS 612
           K++S S  K+R    P   +  + +   R R  ST+  PK       S+     TS++ +
Sbjct: 217 KHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPK-------SRRAHRSTSADSA 269

Query: 613 SPEICPNKEKPFMKLKENGRAISRSSSSTSSVSSTAGEGEAMEEGDSGGSQPST------ 666
           S              K +  A++  S S +S     G+    E G +   +PS+      
Sbjct: 270 SSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATK 329

Query: 667 --TSPF------KQEVFVYSPSPSSESPSLG---AAATPIIMSR 699
             +SP+      K+E     PSPS E  S G    A TP++  R
Sbjct: 330 QPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAER 373



 Score = 33.9 bits (76), Expect = 0.55
 Identities = 42/163 (25%), Positives = 59/163 (36%), Gaps = 27/163 (16%)

Query: 555  QSRSPIKRRSGLFPRLHTGSEGQGDSRARCDSTSSTPKTPDGGHSSQEIKSETSSNPSSP 614
            + ++P  R      R  + S+G+G S     ST S+P+ P         KS T+   S  
Sbjct: 1623 EPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPP--------KSRTARRGS-- 1672

Query: 615  EICPNKEKPFMKLKENGRAISRSSSSTSSVSSTAGEGEAMEEGDSGGSQPSTTSPFKQEV 674
                 +  P  K K       RSS S+  ++  A          S     S T P  +  
Sbjct: 1673 -----RSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRR- 1726

Query: 675  FVYSPSPSSESPSLGAAATPIIMSRSPTDAKSRNSPRSNLKFR 717
                 SPS  SP       P   SRS    +S +SPR+    R
Sbjct: 1727 -----SPSVSSPE------PAEKSRSSRRRRSASSPRTKTTSR 1758



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 45/186 (24%), Positives = 70/186 (37%), Gaps = 23/186 (12%)

Query: 544  SPPVVAATVKNQSRSPIKRRSGLFPRLHTGSE------------GQGDSRARCDSTSSTP 591
            SP V +     +SRS  +RRS   PR  T S              +  SR+R + T +T 
Sbjct: 1727 SPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTR 1786

Query: 592  KTPDGGHSSQEIKSETSSNPSSPEICPNKEKPFMKLKENGRAISRSSSSTSSVSSTAGEG 651
            +    G SSQ        + S   +   +         + R+ +R  SS +S     G  
Sbjct: 1787 RRDRSG-SSQSTSRRRQRSRSRSRVTRRRRG---GSGYHSRSPARQESSRTSSRRRRGRS 1842

Query: 652  EAMEEGDSGGSQPSTTSPFKQEVFVYSPSPSSESPSLGAAATPIIMSRSPTDAKSRNSPR 711
                         ++ +P+K+     SP+    S S     TP+I  R    ++SR SP 
Sbjct: 1843 RTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRS----RTPLISRRR---SRSRTSPV 1895

Query: 712  SNLKFR 717
            S  + R
Sbjct: 1896 SRRRSR 1901


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 52/231 (22%), Positives = 94/231 (40%), Gaps = 21/231 (9%)

Query: 496 SFKRAIRVRSH--SMETMVGGQKKSHSGGIPGSLSGGISHNSMEVTKTTFSPPVVAATVK 553
           S K ++R R    SM T+  G+KK      P S  G  S  + ++  +  + P  A+T  
Sbjct: 13  SGKHSMRTRRSRGSMSTLRSGRKKQ-----PASPDGRTSPINEDIRSSGRNSPSAASTSS 67

Query: 554 NQSRSPIKRRSGLFPRLHTGSEGQGDSRARCDSTSSTPKTPDGGHSSQEIKSETSSNPSS 613
           N S++   ++S    +    S  + + R R    S T +      SS++ K++  S P+S
Sbjct: 68  NDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRT--SSKKTKTQEISRPNS 125

Query: 614 PEICPNKEKPFMKLKENGRA----ISRSSSSTSSVSSTAGEGEAMEEGDSGGSQPSTTSP 669
           P     +      + + G +    I + + STS    +  + E+  +  +         P
Sbjct: 126 PSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPP 185

Query: 670 FKQEVFVYSPSPSSESPSLGAAATP--------IIMSRSPTDAKSRNSPRS 712
             Q     +P+PSS  P      TP        +    SPT +++ N P++
Sbjct: 186 ALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQA 236


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 52/231 (22%), Positives = 94/231 (40%), Gaps = 21/231 (9%)

Query: 496 SFKRAIRVRSH--SMETMVGGQKKSHSGGIPGSLSGGISHNSMEVTKTTFSPPVVAATVK 553
           S K ++R R    SM T+  G+KK      P S  G  S  + ++  +  + P  A+T  
Sbjct: 567 SGKHSMRTRRSRGSMSTLRSGRKKQ-----PASPDGRTSPINEDIRSSGRNSPSAASTSS 621

Query: 554 NQSRSPIKRRSGLFPRLHTGSEGQGDSRARCDSTSSTPKTPDGGHSSQEIKSETSSNPSS 613
           N S++   ++S    +    S  + + R R    S T +      SS++ K++  S P+S
Sbjct: 622 NDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRT--SSKKTKTQEISRPNS 679

Query: 614 PEICPNKEKPFMKLKENGRA----ISRSSSSTSSVSSTAGEGEAMEEGDSGGSQPSTTSP 669
           P     +      + + G +    I + + STS    +  + E+  +  +         P
Sbjct: 680 PSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPP 739

Query: 670 FKQEVFVYSPSPSSESPSLGAAATP--------IIMSRSPTDAKSRNSPRS 712
             Q     +P+PSS  P      TP        +    SPT +++ N P++
Sbjct: 740 ALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQA 790


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 52/231 (22%), Positives = 94/231 (40%), Gaps = 21/231 (9%)

Query: 496 SFKRAIRVRSH--SMETMVGGQKKSHSGGIPGSLSGGISHNSMEVTKTTFSPPVVAATVK 553
           S K ++R R    SM T+  G+KK      P S  G  S  + ++  +  + P  A+T  
Sbjct: 567 SGKHSMRTRRSRGSMSTLRSGRKKQ-----PASPDGRTSPINEDIRSSGRNSPSAASTSS 621

Query: 554 NQSRSPIKRRSGLFPRLHTGSEGQGDSRARCDSTSSTPKTPDGGHSSQEIKSETSSNPSS 613
           N S++   ++S    +    S  + + R R    S T +      SS++ K++  S P+S
Sbjct: 622 NDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRT--SSKKTKTQEISRPNS 679

Query: 614 PEICPNKEKPFMKLKENGRA----ISRSSSSTSSVSSTAGEGEAMEEGDSGGSQPSTTSP 669
           P     +      + + G +    I + + STS    +  + E+  +  +         P
Sbjct: 680 PSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPP 739

Query: 670 FKQEVFVYSPSPSSESPSLGAAATP--------IIMSRSPTDAKSRNSPRS 712
             Q     +P+PSS  P      TP        +    SPT +++ N P++
Sbjct: 740 ALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQA 790


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 46.6 bits (109), Expect = 8e-05
 Identities = 54/211 (25%), Positives = 84/211 (39%), Gaps = 21/211 (9%)

Query: 507  SMETMVGGQKKSHSGGIPGSLSGGISHNSMEVTKTTFSPPVVAATVKNQSRSPIKRRSGL 566
            SM ++  G++ + S   PGS     +H+++    TT +P +   +    S SP    + +
Sbjct: 2345 SMTSLGVGEESTTSRSQPGS-----THSTVSPASTT-TPGLSEESTTVYSSSPGSTETTV 2398

Query: 567  FPRLHTGS---EGQGDSRARCDSTSSTPKTPDGGHSSQEIKSETSSNPSSPEICPNKEKP 623
            FPR  T S   E      +R  ST +T  T D   S   +  E+++ P SP         
Sbjct: 2399 FPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSG--LTEESTAFPGSPASTQTGLPA 2456

Query: 624  FMKLKENGRAISRSSSSTSSVSSTAGEGEAMEEGDSGGSQPSTTSPFKQEVFVYSPSPSS 683
             +   + G   +   SS+ S  +T     +   G  G S PS  SP   E      SP+ 
Sbjct: 2457 TLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPT- 2515

Query: 684  ESPSLGAAATPIIMSRSPTDAKSRNSPRSNL 714
                     TP +  +S T   S  SP + L
Sbjct: 2516 ---------TPSLSEKSTTFYTSPRSPDATL 2537



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 54/211 (25%), Positives = 84/211 (39%), Gaps = 21/211 (9%)

Query: 507  SMETMVGGQKKSHSGGIPGSLSGGISHNSMEVTKTTFSPPVVAATVKNQSRSPIKRRSGL 566
            SM ++  G++ + S   PGS     +H+++    TT +P +   +    S SP    + +
Sbjct: 2819 SMTSLGVGEESTTSRSQPGS-----THSTVSPASTT-TPGLSEESTTVYSSSPGSTETTV 2872

Query: 567  FPRLHTGS---EGQGDSRARCDSTSSTPKTPDGGHSSQEIKSETSSNPSSPEICPNKEKP 623
            FPR  T S   E      +R  ST +T  T D   S   +  E+++ P SP         
Sbjct: 2873 FPRSTTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSG--LTEESTAFPGSPASTQTGLPA 2930

Query: 624  FMKLKENGRAISRSSSSTSSVSSTAGEGEAMEEGDSGGSQPSTTSPFKQEVFVYSPSPSS 683
             +   + G   +   SS+ S  +T     +   G  G S PS  SP   E      SP+ 
Sbjct: 2931 TLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPT- 2989

Query: 684  ESPSLGAAATPIIMSRSPTDAKSRNSPRSNL 714
                     TP +  +S T   S  SP + L
Sbjct: 2990 ---------TPSLSEKSTTFYTSPRSPDATL 3011



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 53/211 (25%), Positives = 83/211 (39%), Gaps = 21/211 (9%)

Query: 507  SMETMVGGQKKSHSGGIPGSLSGGISHNSMEVTKTTFSPPVVAATVKNQSRSPIKRRSGL 566
            SM ++  G++ + S   PGS     +H+++    TT +P +   +    S SP    + +
Sbjct: 3902 SMTSLGVGEESTTSRSQPGS-----THSTVSPASTT-TPGLSEESTTVYSSSPGSTETTV 3955

Query: 567  FPRLHTGS---EGQGDSRARCDSTSSTPKTPDGGHSSQEIKSETSSNPSSPEICPNKEKP 623
            FPR  T S   E      +R  ST +T  T D   S   +  E+++ P SP         
Sbjct: 3956 FPRSTTTSVRREEPTTFHSRPASTHTTLFTEDSTTSG--LTEESTAFPGSPASTQTGLPA 4013

Query: 624  FMKLKENGRAISRSSSSTSSVSSTAGEGEAMEEGDSGGSQPSTTSPFKQEVFVYSPSPSS 683
             +   + G   +   SS+ S  +      +   G  G S PS  SP   E      SP+ 
Sbjct: 4014 TLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPT- 4072

Query: 684  ESPSLGAAATPIIMSRSPTDAKSRNSPRSNL 714
                     TP +  +S T   S  SP + L
Sbjct: 4073 ---------TPSLSEKSTTFYTSPRSPDATL 4094



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 54/196 (27%), Positives = 80/196 (40%), Gaps = 25/196 (12%)

Query: 528  SGGISHNSMEVTKTTFSPPVVAAT-VKNQSRSPIKRRSGLFPRLHTGSEGQGDSRARCDS 586
            S G +H ++    TT S  V A+T V + + SP   R+ L P   T    QG+S A    
Sbjct: 2167 SPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSP---RTTLSPASSTSPGLQGESTAFQTH 2223

Query: 587  TSSTPKTPDGGHSSQEIKSETSSNPSSPEICPNKEKPFMKLKE---------NGRAISRS 637
             +ST  TP    ++     E+++   SP   P    P               +    +  
Sbjct: 2224 PASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASG 2283

Query: 638  SSSTSSVSSTAGEGEAMEEGDSGGSQPSTTSPFKQEVFVYSPSPSSESPSLGAAATPIIM 697
            ++ +S+ S+T+G GE+     S GS   TT P            S+ +P L  A+T    
Sbjct: 2284 TTPSSAHSTTSGRGESTTSRISPGSTEITTLP-----------GSTTTPGLSEASTTFYS 2332

Query: 698  S-RSPTDAKSRNSPRS 712
            S RSPT   S  S  S
Sbjct: 2333 SPRSPTTTLSPASMTS 2348



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 54/196 (27%), Positives = 80/196 (40%), Gaps = 25/196 (12%)

Query: 528  SGGISHNSMEVTKTTFSPPVVAAT-VKNQSRSPIKRRSGLFPRLHTGSEGQGDSRARCDS 586
            S G +H ++    TT S  V A+T V + + SP   R+ L P   T    QG+S A    
Sbjct: 3724 SPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSP---RTTLSPASSTSPGLQGESTAFQTH 3780

Query: 587  TSSTPKTPDGGHSSQEIKSETSSNPSSPEICPNKEKPFMKLKE---------NGRAISRS 637
             +ST  TP    ++     E+++   SP   P    P               +    +  
Sbjct: 3781 PASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASG 3840

Query: 638  SSSTSSVSSTAGEGEAMEEGDSGGSQPSTTSPFKQEVFVYSPSPSSESPSLGAAATPIIM 697
            ++ +S+ S+T+G GE+     S GS   TT P            S+ +P L  A+T    
Sbjct: 3841 TTPSSAHSTTSGRGESTTSRISPGSTEITTLP-----------GSTTTPGLSEASTTFYS 3889

Query: 698  S-RSPTDAKSRNSPRS 712
            S RSPT   S  S  S
Sbjct: 3890 SPRSPTTTLSPASMTS 3905



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 57/210 (27%), Positives = 85/210 (40%), Gaps = 30/210 (14%)

Query: 514  GQKKSHSGGIPGSLSGGISHNSMEVTKTTFSPPVVAAT-VKNQSRSPIKRRSGLFPRLHT 572
            GQ+ +     PGS     +H ++    TT S  V A+T V + + SP   R+ L P   T
Sbjct: 1075 GQESTTFHSNPGS-----THTTLFPDSTTSSGIVEASTRVHSSTGSP---RTTLSPASST 1126

Query: 573  GSEGQGDSRARCDSTSSTPKTPDGGHSSQEIKSETSSNPSSPEICPNKEKPFMKLKE--- 629
                QG+S A     +ST  TP    ++     E+++   SP   P    P         
Sbjct: 1127 SPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHS 1186

Query: 630  ------NGRAISRSSSSTSSVSSTAGEGEAMEEGDSGGSQPSTTSPFKQEVFVYSPSPSS 683
                  +    +  ++ +S+ S+T+G GE+     S GS   TT P            S+
Sbjct: 1187 EKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLP-----------GST 1235

Query: 684  ESPSLGAAATPIIMS-RSPTDAKSRNSPRS 712
             +P L  A+T    S RSPT   S  S  S
Sbjct: 1236 TTPGLSEASTTFYSSPRSPTTTLSPASMTS 1265



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 51/187 (27%), Positives = 70/187 (37%), Gaps = 7/187 (3%)

Query: 528  SGGISHNSMEVTKTTFSPPVVAAT-VKNQSRSPIKRRSGLFPRLHTGSEGQGDSRARCDS 586
            S G +H ++    TT S  V A+T V + + SP   R+ L P   T    QG+S      
Sbjct: 2641 SPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSP---RTTLSPASSTSPGLQGESTTFQTH 2697

Query: 587  TSSTPKTPDGGHSSQEIKSETSSNPSSPEICPNKEKPFMKLKENGRAISRSSSSTSSVSS 646
             +ST  TP    ++     E+++   SP   P    P           S    S+   S 
Sbjct: 2698 PASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASG 2757

Query: 647  TAGEGEAMEEGDSGGSQPSTTSPFKQEVFVYSPSPSSESPSLGAAATPIIMS-RSPTDAK 705
            T            G S  S  SP   E+       S+ +P L  A+T    S RSPT   
Sbjct: 2758 TTPSSAHSTTSGRGESTTSRISPGSTEITTL--PGSTTTPGLSEASTTFYSSPRSPTTTL 2815

Query: 706  SRNSPRS 712
            S  S  S
Sbjct: 2816 SPASMTS 2822



 Score = 38.5 bits (88), Expect = 0.022
 Identities = 51/211 (24%), Positives = 81/211 (38%), Gaps = 21/211 (9%)

Query: 507  SMETMVGGQKKSHSGGIPGSLSGGISHNSMEVTKTTFSPPVVAATVKNQSRSPIKRRSGL 566
            SM ++  G++ + S   PGS     +H+++    TT +P +   +    S S     + +
Sbjct: 1262 SMTSLGVGEESTTSRSQPGS-----THSTVSPASTT-TPGLSEESTTVYSSSRGSTETTV 1315

Query: 567  FPRLHTGS---EGQGDSRARCDSTSSTPKTPDGGHSSQEIKSETSSNPSSPEICPNKEKP 623
            FP   T S   E      +R  ST +T  T D   S   +  E+++ P SP         
Sbjct: 1316 FPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSG--LTEESTAFPGSPASTQTGLPA 1373

Query: 624  FMKLKENGRAISRSSSSTSSVSSTAGEGEAMEEGDSGGSQPSTTSPFKQEVFVYSPSPSS 683
             +   + G   +   SS+ S  +      +   G  G S PS  SP   E      SP+ 
Sbjct: 1374 TLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPT- 1432

Query: 684  ESPSLGAAATPIIMSRSPTDAKSRNSPRSNL 714
                     TP +  +S T   S  SP + L
Sbjct: 1433 ---------TPSLSEKSTTFYTSPRSPDATL 1454



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 55/202 (27%), Positives = 72/202 (35%), Gaps = 27/202 (13%)

Query: 532  SHNSMEVTKTTFSPP--VVAATVKNQSRSPIKRRSGLFPRLHTGSEGQGDSRARC---DS 586
            SH+S + T T   P     +  +   + SPI   S     L   +   G S        S
Sbjct: 4636 SHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSS 4695

Query: 587  TSSTPKTPDGGHSSQEIKSETSSNP-SSPEICPNKEKPFMK----LKENGRAISRSSSST 641
             SSTP T     S+   +SE S+   SSP        P       L E   A   S  ST
Sbjct: 4696 PSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGST 4755

Query: 642  SSV-----SSTAGEGEAMEEGDSG-----GSQPSTTSPFKQEVFVYSPSPSSESPSLGAA 691
             ++     S+ +G  E      S       S PSTTS   +E   Y  SP       G+ 
Sbjct: 4756 QTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSP-------GSI 4808

Query: 692  ATPIIMSRSPTDAKSRNSPRSN 713
            AT      S T  +S  S  S+
Sbjct: 4809 ATTHFPESSTTSGRSEESTASH 4830



 Score = 35.8 bits (81), Expect = 0.14
 Identities = 54/227 (23%), Positives = 89/227 (39%), Gaps = 26/227 (11%)

Query: 518  SHSGGIPGSLS-------GGISHNSMEVTKTTFSP-PVVAATVKNQSR----SPIKRRSG 565
            +H+   PGS +          SH+S   T TT SP    A+++  +S     SP    + 
Sbjct: 1729 THTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETT 1788

Query: 566  LFPRLHTGSEGQGDSRARCDSTSSTPKT---PDGGHSSQEIKSETSSNPSSPEICPNKEK 622
            L P  +T + G  ++     S++ +P T   P G  + Q   +   S PSS +  P    
Sbjct: 1789 LLPD-NTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPT 1847

Query: 623  PFMKLKENGRAISRSSSSTSSVSSTAGEGEAMEEGDSGGSQPSTTSPFKQEVFVYSPSPS 682
                       +  S++S  S SST     +      G S+ STT          +PSP+
Sbjct: 1848 T------TSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPA 1901

Query: 683  SESPSLGAAATPIIMSRSPTDAKSRNSPRSNL---KFRFDKLSHASS 726
              + S G          SP   ++ + P S+    +    + SH+S+
Sbjct: 1902 RSTTS-GLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSST 1947



 Score = 35.4 bits (80), Expect = 0.19
 Identities = 54/218 (24%), Positives = 84/218 (38%), Gaps = 17/218 (7%)

Query: 505  SHSMETMVGGQKKSHSGGIPG-SLSGGISHNSMEVTKTTFSP-PVVAATVKNQSR----S 558
            SHS    +       S  +PG S     SH+S   T TT SP    A+++  +S     S
Sbjct: 4362 SHSRPGSMHTTAFPSSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSS 4421

Query: 559  PIKRRSGLFPRLHTGSEGQGDSRARCDSTSSTPKT---PDGGHSSQEIKSETSSNPSSPE 615
            P    + L P  +T + G  ++     S++ +P T   P G  + Q   +   S P+S +
Sbjct: 4422 PGSTETTLLPD-NTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKD 4480

Query: 616  ICPNKEKPFMKLKENGRAISRSSSSTSSVSSTAGEGEAMEEGDSGGSQPSTTSPFKQEVF 675
              P               +  S++S  S SST     +      G S+ STT        
Sbjct: 4481 TTPAPPTT------TSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVAT 4534

Query: 676  VYSPSPSSESPSLGAAATPIIMSRSPTDAKSRNSPRSN 713
              +PSP+  + S G          SP   ++ + P SN
Sbjct: 4535 ATTPSPARSTTS-GLVEESTTYHSSPGSTQTMHFPESN 4571



 Score = 35.0 bits (79), Expect = 0.25
 Identities = 53/201 (26%), Positives = 74/201 (36%), Gaps = 30/201 (14%)

Query: 533 HNSMEVTKTTFSPPVVAAT--------VKNQSRSPIKRRSGLFPRLHTGSEGQGDSRARC 584
           H+    T+TT  P    A+        V + +RSP    + L P   T  +G+  +    
Sbjct: 724 HSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSP---HTTLSPAGSTTRQGESTTFHSW 780

Query: 585 DSTSSTPKTPDGGHSSQEIKSETS-SNPSS-PEICPNKEKPFMKLKENGRAISRSSSSTS 642
            S+  T   P    S+    S TS  +PSS P    +       L E       S  ST 
Sbjct: 781 PSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQ 840

Query: 643 SV-----SSTAGEGEAMEEGDSG-----GSQPSTTSPFKQEVFVYSPSPSSESPSLGAAA 692
           ++      +T+G GE      S       S PSTTS   +E   Y  SP       G+ A
Sbjct: 841 TMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSP-------GSTA 893

Query: 693 TPIIMSRSPTDAKSRNSPRSN 713
           T      S T  +S  S  S+
Sbjct: 894 TTHFPDSSTTSGRSEESTASH 914



 Score = 35.0 bits (79), Expect = 0.25
 Identities = 42/143 (29%), Positives = 54/143 (37%), Gaps = 22/143 (15%)

Query: 586  STSSTPKTPDGGHSSQEIKSETSSNP-SSPEICPNKEKPFMK----LKENGRAISRSSSS 640
            S SSTP T     S+   +SE S+   SSP        P       L E       S  S
Sbjct: 4502 SPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGS 4561

Query: 641  TSSV-----SSTAGEGEAMEEGDSG-----GSQPSTTSPFKQEVFVYSPSPSSESPSLGA 690
            T ++     ++T+G GE      S       S PSTTS   +E   Y  SP       G+
Sbjct: 4562 TQTMHFPESNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSP-------GS 4614

Query: 691  AATPIIMSRSPTDAKSRNSPRSN 713
             AT      S T  +S  S  S+
Sbjct: 4615 TATTHFPDSSTTSGRSEESTASH 4637



 Score = 34.7 bits (78), Expect = 0.32
 Identities = 42/143 (29%), Positives = 53/143 (37%), Gaps = 22/143 (15%)

Query: 586  STSSTPKTPDGGHSSQEIKSETSSNP-SSPEICPNKEKPFMK----LKENGRAISRSSSS 640
            S SSTP T     S+   +SE S+   SSP        P       L E       S  S
Sbjct: 3419 SPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGS 3478

Query: 641  TSSV-----SSTAGEGEAMEEGDSG-----GSQPSTTSPFKQEVFVYSPSPSSESPSLGA 690
            T ++      +T+G GE      S       S PSTTS   +E   Y  SP       G+
Sbjct: 3479 TQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSP-------GS 3531

Query: 691  AATPIIMSRSPTDAKSRNSPRSN 713
             AT      S T  +S  S  S+
Sbjct: 3532 TATTHFPDSSTTSGRSEESTASH 3554



 Score = 33.9 bits (76), Expect = 0.55
 Identities = 42/143 (29%), Positives = 53/143 (37%), Gaps = 22/143 (15%)

Query: 586  STSSTPKTPDGGHSSQEIKSETSSNP-SSPEICPNKEKPFMK----LKENGRAISRSSSS 640
            S SSTP T     S+   +SE S+   SSP        P       L E   A   S  S
Sbjct: 1862 SPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGS 1921

Query: 641  TSSV-----SSTAGEGEAMEEGDSG-----GSQPSTTSPFKQEVFVYSPSPSSESPSLGA 690
            T ++     S+ +G  E      S       S PSTTS   +E   Y  SP       G+
Sbjct: 1922 TQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSP-------GS 1974

Query: 691  AATPIIMSRSPTDAKSRNSPRSN 713
             AT      S T  +S  S  S+
Sbjct: 1975 TATTHFPDSSTTSGRSEESTASH 1997



 Score = 33.1 bits (74), Expect = 0.94
 Identities = 49/211 (23%), Positives = 82/211 (38%), Gaps = 23/211 (10%)

Query: 518  SHSGGIPGSLS-------GGISHNSMEVTKTTFSP-PVVAATVKNQSRS----PIKRRSG 565
            +H+   PGS +          SH+S   T TT SP    A+++  +S +    P    + 
Sbjct: 3286 THTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPGSTETT 3345

Query: 566  LFPRLHTGSEGQGDSRARCDSTSSTPKT---PDGGHSSQEIKSETSSNPSSPEICPNKEK 622
            L P  +T + G  ++     S++ +P T   P G  + Q   +   S P+S +  P    
Sbjct: 3346 LLPD-NTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPT 3404

Query: 623  PFMKLKENGRAISRSSSSTSSVSSTAGEGEAMEEGDSGGSQPSTTSPFKQEVFVYSPSPS 682
                       +  S++S  S SST     +      G S+ STT          +PSP+
Sbjct: 3405 T------TSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPA 3458

Query: 683  SESPSLGAAATPIIMSRSPTDAKSRNSPRSN 713
              + S G          SP   ++ + P S+
Sbjct: 3459 RSTTS-GLVEESTTYHSSPGSTQTMHFPESD 3488


>gi|239758148 PREDICTED: similar to mucin 11 [Homo sapiens]
          Length = 587

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 51/200 (25%), Positives = 78/200 (39%), Gaps = 16/200 (8%)

Query: 518 SHSGGIPGSLSGGISHNSMEVTKTTFSPPVVAATVKNQS----RSPIKRRSGLFPRLHTG 573
           S S G+ G  +   +H +   T TT SPP  A     +S    RSP    +  FP   T 
Sbjct: 284 STSPGLQGESTAFQTHPAS--THTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTT 341

Query: 574 SEGQGDSRARCDSTSSTPKTPDGGHSSQE-IKSETSSNPSSPEICPNKEKPFMKLKENGR 632
           S     S     S  ++  TP   HS+   +  E+S++ S P        P         
Sbjct: 342 SGHSEKSTIFHSSPDASGTTPSSAHSTTSGVSEESSTSHSQPGSTHTTAFP--------D 393

Query: 633 AISRSSSSTSSVSSTAGEGEAMEEGDSGGSQPSTTSPFKQEVFVYSPSPSSESPSLGAAA 692
           + + S  S    +S + +G      D+  S P TT+   +    Y   PSS +P+   +A
Sbjct: 394 STTTSGLSQEPTTSHSSQGSTEATLDTTPSPPGTTAAPVEVSTTYHSRPSS-TPTTHFSA 452

Query: 693 TPIIMSRSPTDAKSRNSPRS 712
           +   + RS       +SP S
Sbjct: 453 SSTTLGRSEESTTVHSSPGS 472



 Score = 38.9 bits (89), Expect = 0.017
 Identities = 48/181 (26%), Positives = 74/181 (40%), Gaps = 16/181 (8%)

Query: 528 SGGISHNSMEVTKTTFSPPVVAAT-VKNQSRSPIKRRSGLFPRLHTGSEGQGDSRARCDS 586
           S G +H ++    TT S  V A+T V + + SP   R+ L P   T    QG+S A    
Sbjct: 243 SPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSP---RTTLSPASSTSPGLQGESTAFQTH 299

Query: 587 TSSTPKTPDGGHSSQEIKSETSSNPSSPEICPNKEKPFMKLKENGRAISRSSSSTSSVSS 646
            +ST  TP    ++     E+++   SP   P    P           + S++S  S  S
Sbjct: 300 PASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFP-----------ASSTTSGHSEKS 348

Query: 647 TAGEGEAMEEGDSGGSQPSTTSPFKQEVFVYSPSP-SSESPSLGAAATPIIMSRSPTDAK 705
           T         G +  S  STTS   +E       P S+ + +   + T   +S+ PT + 
Sbjct: 349 TIFHSSPDASGTTPSSAHSTTSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSH 408

Query: 706 S 706
           S
Sbjct: 409 S 409


>gi|239752490 PREDICTED: similar to Mucin-12 [Homo sapiens]
          Length = 456

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 51/200 (25%), Positives = 78/200 (39%), Gaps = 16/200 (8%)

Query: 518 SHSGGIPGSLSGGISHNSMEVTKTTFSPPVVAATVKNQS----RSPIKRRSGLFPRLHTG 573
           S S G+ G  +   +H +   T TT SPP  A     +S    RSP    +  FP   T 
Sbjct: 178 STSPGLQGESTAFQTHPAS--THTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTT 235

Query: 574 SEGQGDSRARCDSTSSTPKTPDGGHSSQE-IKSETSSNPSSPEICPNKEKPFMKLKENGR 632
           S     S     S  ++  TP   HS+   +  E+S++ S P        P         
Sbjct: 236 SGHSEKSTIFHSSPDASGTTPSSAHSTTSGVSEESSTSHSQPGSTHTTAFP--------D 287

Query: 633 AISRSSSSTSSVSSTAGEGEAMEEGDSGGSQPSTTSPFKQEVFVYSPSPSSESPSLGAAA 692
           + + S  S    +S + +G      D+  S P TT+   +    Y   PSS +P+   +A
Sbjct: 288 STTTSGLSQEPTTSHSSQGSTEATLDTTPSPPGTTAAPVEVSTTYHSRPSS-TPTTHFSA 346

Query: 693 TPIIMSRSPTDAKSRNSPRS 712
           +   + RS       +SP S
Sbjct: 347 SSTTLGRSEESTTVHSSPGS 366



 Score = 38.9 bits (89), Expect = 0.017
 Identities = 48/181 (26%), Positives = 74/181 (40%), Gaps = 16/181 (8%)

Query: 528 SGGISHNSMEVTKTTFSPPVVAAT-VKNQSRSPIKRRSGLFPRLHTGSEGQGDSRARCDS 586
           S G +H ++    TT S  V A+T V + + SP   R+ L P   T    QG+S A    
Sbjct: 137 SPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSP---RTTLSPASSTSPGLQGESTAFQTH 193

Query: 587 TSSTPKTPDGGHSSQEIKSETSSNPSSPEICPNKEKPFMKLKENGRAISRSSSSTSSVSS 646
            +ST  TP    ++     E+++   SP   P    P           + S++S  S  S
Sbjct: 194 PASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFP-----------ASSTTSGHSEKS 242

Query: 647 TAGEGEAMEEGDSGGSQPSTTSPFKQEVFVYSPSP-SSESPSLGAAATPIIMSRSPTDAK 705
           T         G +  S  STTS   +E       P S+ + +   + T   +S+ PT + 
Sbjct: 243 TIFHSSPDASGTTPSSAHSTTSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSH 302

Query: 706 S 706
           S
Sbjct: 303 S 303


>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
           sapiens]
          Length = 2036

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 57/210 (27%), Positives = 85/210 (40%), Gaps = 30/210 (14%)

Query: 514 GQKKSHSGGIPGSLSGGISHNSMEVTKTTFSPPVVAAT-VKNQSRSPIKRRSGLFPRLHT 572
           GQ+ +     PGS     +H ++    TT S  V A+T V + + SP   R+ L P   T
Sbjct: 562 GQESTTFHSNPGS-----THTTLFPDSTTSSGIVEASTRVHSSTGSP---RTTLSPASST 613

Query: 573 GSEGQGDSRARCDSTSSTPKTPDGGHSSQEIKSETSSNPSSPEICPNKEKPFMKLKE--- 629
               QG+S A     +ST  TP    ++     E+++   SP   P    P         
Sbjct: 614 SPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHS 673

Query: 630 ------NGRAISRSSSSTSSVSSTAGEGEAMEEGDSGGSQPSTTSPFKQEVFVYSPSPSS 683
                 +    +  ++ +S+ S+T+G GE+     S GS   TT P            S+
Sbjct: 674 EKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLP-----------GST 722

Query: 684 ESPSLGAAATPIIMS-RSPTDAKSRNSPRS 712
            +P L  A+T    S RSPT   S  S  S
Sbjct: 723 TTPGLSEASTTFYSSPRSPTTTLSPASMTS 752



 Score = 38.5 bits (88), Expect = 0.022
 Identities = 51/211 (24%), Positives = 81/211 (38%), Gaps = 21/211 (9%)

Query: 507 SMETMVGGQKKSHSGGIPGSLSGGISHNSMEVTKTTFSPPVVAATVKNQSRSPIKRRSGL 566
           SM ++  G++ + S   PGS     +H+++    TT +P +   +    S S     + +
Sbjct: 749 SMTSLGVGEESTTSRSQPGS-----THSTVSPASTT-TPGLSEESTTVYSSSRGSTETTV 802

Query: 567 FPRLHTGS---EGQGDSRARCDSTSSTPKTPDGGHSSQEIKSETSSNPSSPEICPNKEKP 623
           FP   T S   E      +R  ST +T  T D   S   +  E+++ P SP         
Sbjct: 803 FPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSG--LTEESTAFPGSPASTQTGLPA 860

Query: 624 FMKLKENGRAISRSSSSTSSVSSTAGEGEAMEEGDSGGSQPSTTSPFKQEVFVYSPSPSS 683
            +   + G   +   SS+ S  +      +   G  G S PS  SP   E      SP+ 
Sbjct: 861 TLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPT- 919

Query: 684 ESPSLGAAATPIIMSRSPTDAKSRNSPRSNL 714
                    TP +  +S T   S  SP + L
Sbjct: 920 ---------TPSLSEKSTTFYTSPRSPDATL 941



 Score = 35.8 bits (81), Expect = 0.14
 Identities = 54/227 (23%), Positives = 89/227 (39%), Gaps = 26/227 (11%)

Query: 518  SHSGGIPGSLS-------GGISHNSMEVTKTTFSP-PVVAATVKNQSR----SPIKRRSG 565
            +H+   PGS +          SH+S   T TT SP    A+++  +S     SP    + 
Sbjct: 1216 THTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETT 1275

Query: 566  LFPRLHTGSEGQGDSRARCDSTSSTPKT---PDGGHSSQEIKSETSSNPSSPEICPNKEK 622
            L P  +T + G  ++     S++ +P T   P G  + Q   +   S PSS +  P    
Sbjct: 1276 LLPD-NTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPT 1334

Query: 623  PFMKLKENGRAISRSSSSTSSVSSTAGEGEAMEEGDSGGSQPSTTSPFKQEVFVYSPSPS 682
                       +  S++S  S SST     +      G S+ STT          +PSP+
Sbjct: 1335 T------TSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPA 1388

Query: 683  SESPSLGAAATPIIMSRSPTDAKSRNSPRSNL---KFRFDKLSHASS 726
              + S G          SP   ++ + P S+    +    + SH+S+
Sbjct: 1389 RSTTS-GLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSST 1434



 Score = 35.0 bits (79), Expect = 0.25
 Identities = 53/201 (26%), Positives = 74/201 (36%), Gaps = 30/201 (14%)

Query: 533 HNSMEVTKTTFSPPVVAAT--------VKNQSRSPIKRRSGLFPRLHTGSEGQGDSRARC 584
           H+    T+TT  P    A+        V + +RSP    + L P   T  +G+  +    
Sbjct: 211 HSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSP---HTTLSPAGSTTRQGESTTFHSW 267

Query: 585 DSTSSTPKTPDGGHSSQEIKSETS-SNPSS-PEICPNKEKPFMKLKENGRAISRSSSSTS 642
            S+  T   P    S+    S TS  +PSS P    +       L E       S  ST 
Sbjct: 268 PSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQ 327

Query: 643 SV-----SSTAGEGEAMEEGDSG-----GSQPSTTSPFKQEVFVYSPSPSSESPSLGAAA 692
           ++      +T+G GE      S       S PSTTS   +E   Y  SP       G+ A
Sbjct: 328 TMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSP-------GSTA 380

Query: 693 TPIIMSRSPTDAKSRNSPRSN 713
           T      S T  +S  S  S+
Sbjct: 381 TTHFPDSSTTSGRSEESTASH 401



 Score = 33.5 bits (75), Expect = 0.72
 Identities = 42/143 (29%), Positives = 53/143 (37%), Gaps = 22/143 (15%)

Query: 586  STSSTPKTPDGGHSSQEIKSETSSNP-SSPEICPNKEKPFMK----LKENGRAISRSSSS 640
            S SSTP T     S+   +SE S+   SSP        P       L E   A   S  S
Sbjct: 1349 SPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGS 1408

Query: 641  TSSV-----SSTAGEGEAMEEGDSG-----GSQPSTTSPFKQEVFVYSPSPSSESPSLGA 690
            T ++     S+ +G  E      S       S PSTTS   +E   Y  SP       G+
Sbjct: 1409 TQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSP-------GS 1461

Query: 691  AATPIIMSRSPTDAKSRNSPRSN 713
             AT      S T  +S  S  S+
Sbjct: 1462 IATTHFPESSTTSGRSEESTASH 1484


>gi|157384984 transducin-like enhancer protein 3 isoform c [Homo
           sapiens]
          Length = 760

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 31/145 (21%), Positives = 67/145 (46%), Gaps = 13/145 (8%)

Query: 579 DSRARCDSTSSTPKTPDGGHSSQEIKSETSSNPSSPEICPNKEKPFMKLKENGRAISRSS 638
           DS +R DS        DG  S   +   ++ +P++P + P    P   L +  R++ + +
Sbjct: 233 DSLSRYDS--------DGDKSDDLVVDVSNEDPATPRVSPAHSPPENGL-DKARSLKKDA 283

Query: 639 SSTSSVSSTAGEGEAMEEGDSGGSQPSTTSPFKQEVFVYSPSPSSESPSLGAAATPIIMS 698
            ++ +  +++    + +  D G +  S+T   K      +P+P +++P+ G + TP + S
Sbjct: 284 PTSPASVASSSSTPSSKTKDLGHNDKSSTPGLKSN----TPTPRNDAPTPGTSTTPGLRS 339

Query: 699 RSPTDAKSRNSPRSNLKFRFDKLSH 723
              +  ++  S  S+    F  +SH
Sbjct: 340 MPASALRTPISITSSYAAPFAMMSH 364


>gi|42518068 trans-golgi network protein 2 [Homo sapiens]
          Length = 437

 Score = 40.8 bits (94), Expect = 0.005
 Identities = 51/215 (23%), Positives = 80/215 (37%), Gaps = 20/215 (9%)

Query: 507 SMETMVGGQKKSHSGGIPGSLSGGISHNSMEVTKTTFSPPVVAATVKNQSRSPIKRRSGL 566
           S+    GG  KSH    P +     S +S E      +P    A  K Q  S    +SG 
Sbjct: 45  SLSQRPGGSTKSHPE--PQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDS--SNKSGA 100

Query: 567 FPRLHTGSEGQGDSRARC--DSTSS------TPKTPDGGHSSQEIKSETSSNPSSPEICP 618
             +   GS  +  S A+   DSTS       TPK   G   ++    E S N S  E   
Sbjct: 101 EAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKT 160

Query: 619 NKEKPFMKLKENGRAISRSSSSTSSVSSTAGEGEAMEEGDS-GGSQPSTTSPFKQEVFVY 677
            K+ P        ++ S + ++    + +  +G+  ++G S  G++  T      +    
Sbjct: 161 QKDSP-------SKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAE 213

Query: 678 SPSPSSESPSLGAAATPIIMSRSPTDAKSRNSPRS 712
             +P   S   GA     I   S + A+ + S  S
Sbjct: 214 KQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDS 248


>gi|161016767 mucin 21 [Homo sapiens]
          Length = 566

 Score = 40.8 bits (94), Expect = 0.005
 Identities = 39/138 (28%), Positives = 59/138 (42%), Gaps = 4/138 (2%)

Query: 572 TGSEGQGDSRARCDSTSSTPKTPDGGHSSQEIKSETSSNPSSPEICPNKEKPFMKLKENG 631
           T SE    S     +T+S   T   G +S    SE+S+  S      N E        + 
Sbjct: 301 TNSESSTTSSGANTATNSDSSTTSSG-ASTATNSESSTTSSGASTATNSESSTTSSGAS- 358

Query: 632 RAISRSSSSTSSVSSTAGEGEAMEEGDSGGSQPSTTSPFKQEVFVYSPSPSSESPSLGAA 691
            A +  SS+TSS +STA   E+     S G+  +TTS         S + +SES ++ + 
Sbjct: 359 TATNSGSSTTSSGTSTATNSESSTV--SSGASTATTSESSTTSSGASTATNSESSTVSSG 416

Query: 692 ATPIIMSRSPTDAKSRNS 709
           A+    S S T +   N+
Sbjct: 417 ASTATNSESSTTSSGANT 434



 Score = 40.0 bits (92), Expect = 0.008
 Identities = 57/233 (24%), Positives = 89/233 (38%), Gaps = 27/233 (11%)

Query: 500 AIRVRSHSMETMVGGQKKSHSGGIPGSLSGGISHNSMEVTKTTFSPPVVAATVKNQSRSP 559
           +I   S S  T  G    ++S     S     + NS   T ++      A+T  N   S 
Sbjct: 103 SIATNSESSTTSSGASTATNSESSTPSSGASTATNSDSSTTSSG-----ASTATNSDSST 157

Query: 560 IKRRSGLFPRLHTGSEGQGDSRARCDSTSSTPKTPDGGHSSQEIKSETSSNPSSPEICPN 619
               +       + +   G S A  +S SST  +     +S    SE+S+  S      N
Sbjct: 158 TSSEASTATNSESSTTSSGASTAT-NSESSTVSS----RASTATNSESSTTSSGASTATN 212

Query: 620 KEKPFMKLKENGRAISRSSSSTSSVSSTAGEGEAMEEGDSGG----SQPSTTSPFKQEVF 675
            E         G A +  SS+TSS +STA   E+       G    S+ STTS       
Sbjct: 213 SESRTTS-NGAGTATNSESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGA---- 267

Query: 676 VYSPSPSSESPSLGAAATPIIMSRSPTDAKSRNSPRSNLKFRFDKLSHASSGA 728
               + +SES ++ +  + +  S S T +   N+  ++      + S  SSGA
Sbjct: 268 --GTATNSESSTVSSGISTVTNSESSTPSSGANTATNS------ESSTTSSGA 312



 Score = 39.3 bits (90), Expect = 0.013
 Identities = 45/195 (23%), Positives = 77/195 (39%), Gaps = 16/195 (8%)

Query: 503 VRSHSMETMVGGQKKSHSGGIP-------GSLSGGISHNSMEVTKTTFSPPVVAATVKNQ 555
           V S+ +  +   +  + S GI         ++S GIS  +   + TT S    A+T  N 
Sbjct: 67  VTSNGVSIVTNSEFHTTSSGISTATNSEFSTVSSGISIATNSESSTTSSG---ASTATNS 123

Query: 556 SRSPIKRRSGLFPRLHTGSEGQGDSRARCDSTSSTPKTPDGGHSSQEIKSETSSNPSSPE 615
             S     +       + +   G S A    +S+T        +S    SE+S+  S   
Sbjct: 124 ESSTPSSGASTATNSDSSTTSSGASTATNSDSSTT-----SSEASTATNSESSTTSSGAS 178

Query: 616 ICPNKEKPFMKLKENGRAISRSSSSTSSVSSTAGEGEAMEEGDSGGSQPSTTSPFKQEVF 675
              N E   +  + +  A +  SS+TSS +STA   E+    +  G+  ++ S       
Sbjct: 179 TATNSESSTVSSRAS-TATNSESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGA 237

Query: 676 VYSPSPSSESPSLGA 690
             + +  S +PS GA
Sbjct: 238 STATNSESSTPSSGA 252


>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
          Length = 653

 Score = 40.4 bits (93), Expect = 0.006
 Identities = 52/211 (24%), Positives = 78/211 (36%), Gaps = 21/211 (9%)

Query: 504 RSHSMETMVGGQKKSHSGGIPGSLSGGISHNSMEVTKTTFSPPVVAATVKNQSRSPIKRR 563
           R+ S      G+     G  PGS  G   H      +    PP       + S     RR
Sbjct: 425 RARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKER----PPRARPASTSPSPGAHGRR 480

Query: 564 SGLFPRLHTGSEGQGDSRARCDSTSSTPKTPDGGHSSQEIKSETSSN-PSSPEICPNKEK 622
            G         EG+  SR    S    P++     S  + +S ++   P SP   P+ +K
Sbjct: 481 GG--------PEGKSSSR----SPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKK 528

Query: 623 PFMKLKEN-GRAISRSSSSTSSVSSTAGEG---EAMEEGDSGGSQPSTTSPFKQEVFVYS 678
           P  + K+  GRA    + +T +   +       +   +  S       TS  K+ +  Y 
Sbjct: 529 PLSRDKDGEGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYR 588

Query: 679 PSPSSESPSLGAAATPIIMSRSPTDAKSRNS 709
           PSPSS S  L +  +    SRSP+   S  S
Sbjct: 589 PSPSSSSSCLSSDYSTRSHSRSPSPGHSHGS 619



 Score = 31.6 bits (70), Expect = 2.7
 Identities = 46/209 (22%), Positives = 71/209 (33%), Gaps = 22/209 (10%)

Query: 514 GQKKSHSGGIPGSLSGGISHNSMEVTKTTFSPPVVAATVKNQSRSPIKRRSGLFPRLHTG 573
           GQ+    GG PGS     +H+  +   +  SP V           P + +    PR    
Sbjct: 318 GQRSGAHGGRPGS-----AHSPPDKPSSP-SPRVRDKAAAAAPTPPARGKESPSPRSAPS 371

Query: 574 SEGQGDSRARCDSTSSTPKTPDGGHSSQEIKSETSSNPSSPEICPNKEKPFMKLKENGRA 633
           S+G+G   A         +        +  +S  S+        P    P    +   RA
Sbjct: 372 SQGRGGRAA-----GGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRA 426

Query: 634 ISRSSSSTSSVSSTAGEGEAMEEGDSGGSQPSTTSPFKQEVFVYSPSP-----------S 682
            S S S +   +   G     E G  G  + +   P +      SPSP            
Sbjct: 427 RSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGK 486

Query: 683 SESPSLGAAATPIIMSRSPTDAKSRNSPR 711
           S S S G        SRSP+ ++SR++ +
Sbjct: 487 SSSRSPGPHPRSWSSSRSPSKSRSRSAEK 515


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.131    0.381 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,505,405
Number of Sequences: 37866
Number of extensions: 1668521
Number of successful extensions: 6235
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 42
Number of HSP's successfully gapped in prelim test: 251
Number of HSP's that attempted gapping in prelim test: 5608
Number of HSP's gapped (non-prelim): 745
length of query: 730
length of database: 18,247,518
effective HSP length: 110
effective length of query: 620
effective length of database: 14,082,258
effective search space: 8730999960
effective search space used: 8730999960
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.