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Search of human proteins with 155722987
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|155722987 elongation factor, RNA polymerase II, 2 [Homo
sapiens]
(640 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|155722987 elongation factor, RNA polymerase II, 2 [Homo sapiens] 1286 0.0
gi|5729812 elongation factor RNA polymerase II [Homo sapiens] 553 e-157
gi|13376768 elongation factor RNA polymerase II-like 3 [Homo sap... 131 2e-30
gi|84370252 MARVEL domain containing 2 isoform 1 [Homo sapiens] 91 4e-18
gi|4505487 occludin [Homo sapiens] 70 5e-12
gi|13375756 occludin/ELL domain containing 1 [Homo sapiens] 59 1e-08
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 46 9e-05
gi|40788007 FYN binding protein (FYB-120/130) isoform 2 [Homo sa... 45 2e-04
gi|42476118 FYN binding protein (FYB-120/130) isoform 1 [Homo sa... 45 2e-04
gi|55750053 atrophin-1 [Homo sapiens] 43 8e-04
gi|55750041 atrophin-1 [Homo sapiens] 43 8e-04
gi|95147555 microtubule-associated protein 1A [Homo sapiens] 42 0.002
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 42 0.002
gi|126090663 zinc finger homeodomain 4 [Homo sapiens] 42 0.002
gi|7662244 DAZ interacting protein 3, zinc finger [Homo sapiens] 42 0.002
gi|120953251 neuron navigator 3 [Homo sapiens] 41 0.004
gi|189011568 adenomatous polyposis coli [Homo sapiens] 40 0.007
gi|189011566 adenomatous polyposis coli [Homo sapiens] 40 0.007
gi|53759122 adenomatous polyposis coli [Homo sapiens] 40 0.007
gi|125656165 THO complex 2 [Homo sapiens] 40 0.007
gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens] 40 0.007
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] 40 0.009
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 40 0.009
gi|160707881 formin 2 [Homo sapiens] 40 0.009
gi|170016091 odz, odd Oz/ten-m homolog 2 [Homo sapiens] 40 0.009
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi... 40 0.009
gi|28559039 mediator complex subunit 1 [Homo sapiens] 39 0.011
gi|161169015 neuron navigator 2 isoform 3 [Homo sapiens] 39 0.011
gi|161169013 neuron navigator 2 isoform 1 [Homo sapiens] 39 0.011
gi|38044282 neuron navigator 2 isoform 2 [Homo sapiens] 39 0.011
>gi|155722987 elongation factor, RNA polymerase II, 2 [Homo sapiens]
Length = 640
Score = 1286 bits (3328), Expect = 0.0
Identities = 640/640 (100%), Positives = 640/640 (100%)
Query: 1 MAAGGTGGLREEQRYGLSCGRLGQDNITVLHVKLTETAIRALETYQSHKNLIPFRPSIQF 60
MAAGGTGGLREEQRYGLSCGRLGQDNITVLHVKLTETAIRALETYQSHKNLIPFRPSIQF
Sbjct: 1 MAAGGTGGLREEQRYGLSCGRLGQDNITVLHVKLTETAIRALETYQSHKNLIPFRPSIQF 60
Query: 61 QGLHGLVKIPKNDPLNEVHNFNFYLSNVGKDNPQGSFDCIQQTFSSSGASQLNCLGFIQD 120
QGLHGLVKIPKNDPLNEVHNFNFYLSNVGKDNPQGSFDCIQQTFSSSGASQLNCLGFIQD
Sbjct: 61 QGLHGLVKIPKNDPLNEVHNFNFYLSNVGKDNPQGSFDCIQQTFSSSGASQLNCLGFIQD 120
Query: 121 KITVCATNDSYQMTRERMTQAEEESRNRSTKVIKPGGPYVGKRVQIRKAPQAVSDTVPER 180
KITVCATNDSYQMTRERMTQAEEESRNRSTKVIKPGGPYVGKRVQIRKAPQAVSDTVPER
Sbjct: 121 KITVCATNDSYQMTRERMTQAEEESRNRSTKVIKPGGPYVGKRVQIRKAPQAVSDTVPER 180
Query: 181 KRSTPMNPANTIRKTHSSSTISQRPYRDRVIHLLALKAYKKPELLARLQKDGVNQKDKNS 240
KRSTPMNPANTIRKTHSSSTISQRPYRDRVIHLLALKAYKKPELLARLQKDGVNQKDKNS
Sbjct: 181 KRSTPMNPANTIRKTHSSSTISQRPYRDRVIHLLALKAYKKPELLARLQKDGVNQKDKNS 240
Query: 241 LGAILQQVANLNSKDLSYTLKDYVFKELQRDWPGYSEIDRRSLESVLSRKLNPSQNAAGT 300
LGAILQQVANLNSKDLSYTLKDYVFKELQRDWPGYSEIDRRSLESVLSRKLNPSQNAAGT
Sbjct: 241 LGAILQQVANLNSKDLSYTLKDYVFKELQRDWPGYSEIDRRSLESVLSRKLNPSQNAAGT 300
Query: 301 SRSESPVCSSRDAVSSPQKRLLDSEFIDPLMNKKARISHLTNRVPPTLNGHLNPTSEKSA 360
SRSESPVCSSRDAVSSPQKRLLDSEFIDPLMNKKARISHLTNRVPPTLNGHLNPTSEKSA
Sbjct: 301 SRSESPVCSSRDAVSSPQKRLLDSEFIDPLMNKKARISHLTNRVPPTLNGHLNPTSEKSA 360
Query: 361 AGLPLPPAAAAIPTPPPLPSTYLPISHPPQIVNSNSNSPSTPEGRGTQDLPVDSFSQNDS 420
AGLPLPPAAAAIPTPPPLPSTYLPISHPPQIVNSNSNSPSTPEGRGTQDLPVDSFSQNDS
Sbjct: 361 AGLPLPPAAAAIPTPPPLPSTYLPISHPPQIVNSNSNSPSTPEGRGTQDLPVDSFSQNDS 420
Query: 421 IYEDQQDKYTSRTSLETLPPGSVLLKCPKPMEENHSMSHKKSKKKSKKHKEKDQIKKHDI 480
IYEDQQDKYTSRTSLETLPPGSVLLKCPKPMEENHSMSHKKSKKKSKKHKEKDQIKKHDI
Sbjct: 421 IYEDQQDKYTSRTSLETLPPGSVLLKCPKPMEENHSMSHKKSKKKSKKHKEKDQIKKHDI 480
Query: 481 ETIEEKEEDLKREEEIAKLNNSSPNSSGGVKEDCTASMEPSAIELPDYLIKYIAIVSYEQ 540
ETIEEKEEDLKREEEIAKLNNSSPNSSGGVKEDCTASMEPSAIELPDYLIKYIAIVSYEQ
Sbjct: 481 ETIEEKEEDLKREEEIAKLNNSSPNSSGGVKEDCTASMEPSAIELPDYLIKYIAIVSYEQ 540
Query: 541 RQNYKDDFNAEYDEYRALHARMETVARRFIKLDAQRKRLSPGSKEYQNVHEEVLQEYQKI 600
RQNYKDDFNAEYDEYRALHARMETVARRFIKLDAQRKRLSPGSKEYQNVHEEVLQEYQKI
Sbjct: 541 RQNYKDDFNAEYDEYRALHARMETVARRFIKLDAQRKRLSPGSKEYQNVHEEVLQEYQKI 600
Query: 601 KQSSPNYHEEKYRCEYLHNKLAHIKRLIGEFDQQQAESWS 640
KQSSPNYHEEKYRCEYLHNKLAHIKRLIGEFDQQQAESWS
Sbjct: 601 KQSSPNYHEEKYRCEYLHNKLAHIKRLIGEFDQQQAESWS 640
>gi|5729812 elongation factor RNA polymerase II [Homo sapiens]
Length = 621
Score = 553 bits (1426), Expect = e-157
Identities = 306/642 (47%), Positives = 412/642 (64%), Gaps = 36/642 (5%)
Query: 9 LREEQRYGLSCGRLGQDN-ITVLHVKLTETAIRALETYQSHKNLIPFRPSIQFQGLHGLV 67
L+E++ YGLSCGR+ + ++V HVKLT++A+RA E+Y++ ++ + RPSI+FQG G +
Sbjct: 4 LKEDRSYGLSCGRVSDGSKVSVFHVKLTDSALRAFESYRARQDSVSLRPSIRFQGSQGHI 63
Query: 68 KIPKNDPLNEVHNFNFYLSNVGKDNPQGSFDCIQQTFSSSGASQLNCLGFIQDKITVCAT 127
IP+ D E F+FYLSN+G+DNPQGSFDCIQQ SS G L+CLG IQDKITVCAT
Sbjct: 64 SIPQPDCPAEARTFSFYLSNIGRDNPQGSFDCIQQYVSSHGEVHLDCLGSIQDKITVCAT 123
Query: 128 NDSYQMTRERMTQAEEESRNRSTKVIKPGGPYVGKRVQIRKAPQAVSDTVPERKRSTPMN 187
+DSYQ R+ M QAEEE+R+RS VIK GG Y+GK+VQ RK +D VP RKR+TP+N
Sbjct: 124 DDSYQKARQSMAQAEEETRSRSAIVIKAGGRYLGKKVQFRKPAPGATDAVPSRKRATPIN 183
Query: 188 PANTIRKTHSS-----STISQRPYRDRVIHLLALKAYKKPELLARLQKDGVNQKDKNSLG 242
A+ IRK+ +S S +SQRP+RDRV+HLLAL+ Y+K ELL RLQKDG+ Q DK++L
Sbjct: 184 LASAIRKSGASAVSGGSGVSQRPFRDRVLHLLALRPYRKAELLLRLQKDGLTQADKDALD 243
Query: 243 AILQQVANLNSKDLSYTLKDYVFKELQRDWPGYSEIDRRSLESVLSRKLNPSQNAA---G 299
+LQQVAN+++KD + TL+D ++K++Q+DWPGYSE D++ L+ VL RKL Q+ G
Sbjct: 244 GLLQQVANMSAKDGTCTLQDCMYKDVQKDWPGYSEGDQQLLKRVLVRKLCQPQSTGSLLG 303
Query: 300 TSRSESPVCSSRDAVSSPQKRLLDSEFIDPLMNKKARISHLTNRVPPTLNGHLN-PTSEK 358
+ SP + S PQKRL +FIDPL NKK RISH T R P +NG L P +
Sbjct: 304 DPAASSPPGERGRSASPPQKRLQPPDFIDPLANKKPRISHFTQRAQPAVNGKLGVPNGRE 363
Query: 359 SAAGLPLPPAAAAIPTPPPLPSTYLPISHPPQIVNSNSNSPSTPEGRGTQDLPVDSFSQN 418
+ P PPA+ T ST+LP P + S G +D
Sbjct: 364 ALLPTPGPPAS----TDTLSSSTHLPPRLEPPRAHDPLADVSNDLGHSGRDC-------- 411
Query: 419 DSIYEDQQDKYTSRTSLETLPPGSVLLKCPKPMEENHSMSHKKSKKKSKKHKEKDQIKKH 478
E + + T LP +L C +P + S S K KKKSKKHK+K++ +
Sbjct: 412 ----EHGEAAAPAPTVRLGLP---LLTDCAQPSRPHGSPSRSKPKKKSKKHKDKERAAE- 463
Query: 479 DIETIEEKEEDLKREEEIAKLNNSSPNSSGGVKEDCTASMEP-SAIELPDYLIKYIAIVS 537
++ L +P + G+ C+ S P S E PDYL+KY AI S
Sbjct: 464 -----DKPRAQLPDCAPATHATPGAPADTPGLNGTCSVSSVPTSTSETPDYLLKYAAISS 518
Query: 538 YEQRQNYKDDFNAEYDEYRALHARMETVARRFIKLDAQRKRLSPGSKEYQNVHEEVLQEY 597
EQRQ+YK+DFNAEY EYR LHAR+E + RRF +LDAQ ++LS GS+EY+ ++LQEY
Sbjct: 519 SEQRQSYKNDFNAEYSEYRDLHARIERITRRFTQLDAQLRQLSQGSEEYETTRGQILQEY 578
Query: 598 QKIKQSSPNYHEEKYRCEYLHNKLAHIKRLIGEFDQQQAESW 639
+KIK+++ NY +EK+RCEYLH+KLAHIKRLI E+DQ+Q ++W
Sbjct: 579 RKIKKTNTNYSQEKHRCEYLHSKLAHIKRLIAEYDQRQLQAW 620
>gi|13376768 elongation factor RNA polymerase II-like 3 [Homo
sapiens]
Length = 397
Score = 131 bits (329), Expect = 2e-30
Identities = 70/156 (44%), Positives = 106/156 (67%), Gaps = 10/156 (6%)
Query: 485 EKEEDLKREEEIA--KLNNSSPNSSGGVKEDCTASMEPSAIELPDYLIKYIAIVSYEQRQ 542
++ ED ++E+E +L +SS V+ED S PS ++PDYL++Y AI S EQ+
Sbjct: 250 QEGEDWEQEDEDMDPRLEHSS-----SVQED---SESPSPEDIPDYLLQYRAIHSAEQQH 301
Query: 543 NYKDDFNAEYDEYRALHARMETVARRFIKLDAQRKRLSPGSKEYQNVHEEVLQEYQKIKQ 602
Y+ DF +Y EYR LHAR+ T ++RFI+L A+ KR+ G+ EY+ + ++++QEY+K ++
Sbjct: 302 AYEQDFETDYAEYRILHARVGTASQRFIELGAEIKRVRRGTPEYKVLEDKIIQEYKKFRK 361
Query: 603 SSPNYHEEKYRCEYLHNKLAHIKRLIGEFDQQQAES 638
P+Y EEK RCEYLH KL+HIK LI EF+++ S
Sbjct: 362 QYPSYREEKRRCEYLHQKLSHIKGLILEFEEKNRGS 397
Score = 51.6 bits (122), Expect = 2e-06
Identities = 32/103 (31%), Positives = 56/103 (54%), Gaps = 7/103 (6%)
Query: 28 TVLHVKLTETAIRALETYQSHKNLIPFRPSIQFQGLHGLVKIPKNDPLNEVHNFNFYLSN 87
++L ++L + A+RAL+ Q + RP I FQG G +++P F+F +S
Sbjct: 23 SLLLLRLNDAALRALQECQRQQ----VRPVIAFQGHRGYLRLPGP---GWSCLFSFIVSQ 75
Query: 88 VGKDNPQGSFDCIQQTFSSSGASQLNCLGFIQDKITVCATNDS 130
++ GS D + Q F SG + L+CLG +++++ + A DS
Sbjct: 76 CCQEGAGGSLDLVCQRFLRSGPNSLHCLGSLRERLIIWAAMDS 118
>gi|84370252 MARVEL domain containing 2 isoform 1 [Homo sapiens]
Length = 558
Score = 90.5 bits (223), Expect = 4e-18
Identities = 58/169 (34%), Positives = 90/169 (53%), Gaps = 17/169 (10%)
Query: 481 ETIEEKEEDLKREE-EIAKLNNSSPNSSGGVKEDCTASMEPSAIE-------------LP 526
+ I E KR+ E+A + +S KE TA M+P + +P
Sbjct: 381 QEINEPSLSSKRKMCEMATSGDRQRDSEVNFKELRTAKMKPELLSGHIPPGHIPKPIVMP 440
Query: 527 DYLIKYIAIVSYEQRQNYKDDFNAEYDEYRALHARMETVARRFIKLDAQRKRLSPGSKEY 586
DY+ KY I + ++R+ YK F ++ EY+ L A ++ V R+F +LDA RL P E
Sbjct: 441 DYVAKYPVIQTDDERERYKAVFQDQFSEYKELSAEVQAVLRKFDELDAVMSRL-PHHSES 499
Query: 587 QNVHEEV--LQEYQKIKQSSPNYHEEKYRCEYLHNKLAHIKRLIGEFDQ 633
+ HE + + E K K++ P + E+K RC+YL NKL+HIK+ I E+D+
Sbjct: 500 RQEHERISRIHEEFKKKKNDPTFLEKKERCDYLKNKLSHIKQRIQEYDK 548
>gi|4505487 occludin [Homo sapiens]
Length = 522
Score = 70.5 bits (171), Expect = 5e-12
Identities = 42/151 (27%), Positives = 74/151 (49%), Gaps = 6/151 (3%)
Query: 487 EEDLKREEEIAKLNNSSPNSSGGVKEDCTASMEPSAIELPDYLIKYIAIVSYEQRQNYKD 546
E KR + S + D T E D++ +Y I S +QRQ YK
Sbjct: 375 ETPSKRAPAKGRAGRSKRTEQDHYETDYTTGGESCDELEEDWIREYPPITSDQQRQLYKR 434
Query: 547 DFNAEYDEYRALHARMETVARRFIKLDAQRKRLSPGSKEYQNVHEEVLQEYQKIKQ--SS 604
+F+ EY++L + ++ + + +LD + S+EY EY ++KQ S
Sbjct: 435 NFDTGLQEYKSLQSELDEINKELSRLDKELDDYREESEEYM----AAADEYNRLKQVKGS 490
Query: 605 PNYHEEKYRCEYLHNKLAHIKRLIGEFDQQQ 635
+Y +K C+ L +KL+HIK+++G++D+Q+
Sbjct: 491 ADYKSKKNHCKQLKSKLSHIKKMVGDYDRQK 521
>gi|13375756 occludin/ELL domain containing 1 [Homo sapiens]
Length = 264
Score = 58.9 bits (141), Expect = 1e-08
Identities = 58/248 (23%), Positives = 102/248 (41%), Gaps = 22/248 (8%)
Query: 388 PPQIVNSNSNSPSTPEGRGTQDLPVDSFSQNDSIYEDQQDKYTSRTSLETLPPGSVLLKC 447
PP ++ + P R P+ FS+ + SR L T PPG
Sbjct: 29 PPPRAGHDAPRRTRPSARK----PLSCFSRRPMPTREPPKTRGSRGHLHTHPPG------ 78
Query: 448 PKPMEENHSMSHKKSKKKSKKHKEKDQIKKHDIETIEEKEEDLKREEEIAKLNNSSPNSS 507
P ++ + K + + + Q H +T + ED E +++ +
Sbjct: 79 --PGPPLQGLAPRGLKTSAPRPPCQPQPGPHKAKTKKIVFED----ELLSQALLGAKKPI 132
Query: 508 GGVKEDCTASMEPSAIELPDYLIKYIAIVSYEQRQNYKDDFNAEYDEYRALHARMETVAR 567
G + + +P +PDY +KY + S +R Y F +Y E+ L +
Sbjct: 133 GAIPK----GHKPRPHPVPDYELKYPPVSSERERSRYVAVFQDQYGEFLELQHEVGCAQA 188
Query: 568 RFIKLDAQRKRLSPG-SKEYQNVHEEVLQEYQKIKQSSPNYHEEKYRCEYLHNKLAHIKR 626
+ +L+A L P S++ V V +E++ +K+ P + +++ RC YL KL H+K
Sbjct: 189 KLRQLEALLSSLPPPQSQKEAQVAARVWREFE-MKRMDPGFLDKQARCHYLKGKLRHLKT 247
Query: 627 LIGEFDQQ 634
I +FD Q
Sbjct: 248 QIQKFDDQ 255
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 46.2 bits (108), Expect = 9e-05
Identities = 43/162 (26%), Positives = 79/162 (48%), Gaps = 23/162 (14%)
Query: 357 EKSAAGLPLPPAAAAIPTPPPLPSTY-LPISHPPQIVNSNSNSPSTPEGRGT----QDLP 411
E AA PLPP P PPP+P LP PPQ+V TP G G +DL
Sbjct: 831 ELPAAPGPLPPPP---PPPPPVPGPVTLP---PPQLVPEG-----TPGGGGPPALEEDLT 879
Query: 412 VDSFSQNDSIYEDQQDKYTSRTSLETLPPGSVLLKCPKPMEENHSMSHKKSKKKSKKHKE 471
V + + +D E+++++ E + EE+ ++ +++ ++ +E
Sbjct: 880 VININSSDEEEEEEEEEEEEEEEEEEEEEDF------EEEEEDEEEYFEEEEEEEEEFEE 933
Query: 472 KDQIKKHDIETIEEKEEDLKREEEIAKLNNSSPNSSGGVKED 513
+ + ++ ++E EE+EED + EEE+ ++ + ++GG E+
Sbjct: 934 EFEEEEGELEE-EEEEEDEEEEEELEEVEDLEFGTAGGEVEE 974
Score = 35.8 bits (81), Expect = 0.12
Identities = 33/139 (23%), Positives = 56/139 (40%), Gaps = 17/139 (12%)
Query: 364 PLPPAAAAIPTPPPLPSTYLPISHPPQIVNSNSNSPSTPEGRGTQDLPVDSFSQNDSIYE 423
PLPP + TPPP+ T P + PP V + P G P
Sbjct: 797 PLPPPPPSGATPPPIAPTGPPTASPP--VPAKEEPEELPAAPGPLPPPPPP--------P 846
Query: 424 DQQDKYTSRTSLETLPPGSVLLKCPKPMEE-------NHSMSHKKSKKKSKKHKEKDQIK 476
+ + +P G+ P +EE N S ++ +++ ++ +E+++ +
Sbjct: 847 PPVPGPVTLPPPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEE 906
Query: 477 KHDIETIEEKEEDLKREEE 495
+ D E EE EE+ EEE
Sbjct: 907 EEDFEEEEEDEEEYFEEEE 925
Score = 30.8 bits (68), Expect = 4.0
Identities = 30/133 (22%), Positives = 48/133 (36%), Gaps = 9/133 (6%)
Query: 362 GLPLPPAAAAIPTPPPLPSTYLPISHPPQIVNSNSNSPSTPEGRGTQDLPVDSFSQNDSI 421
G P PP PP P P P + P T E RG P + S
Sbjct: 975 GAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQ 1034
Query: 422 YEDQQDKYTSRTSLETLPPGSVLLK-----CPKPMEENHSMSHKKSKKKSKKHKEKDQIK 476
E +++ + PP L++ P +EE K + + E++
Sbjct: 1035 GEVEREGESPAAG----PPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMET 1090
Query: 477 KHDIETIEEKEED 489
+ + E ++EKE+D
Sbjct: 1091 ETEAEALQEKEQD 1103
>gi|40788007 FYN binding protein (FYB-120/130) isoform 2 [Homo
sapiens]
Length = 783
Score = 45.4 bits (106), Expect = 2e-04
Identities = 54/225 (24%), Positives = 92/225 (40%), Gaps = 24/225 (10%)
Query: 284 ESVLSRKLNPSQNAAGTSRSESPVCSSRDAVSSPQKRLLDSEFIDP--LMNKKARISHLT 341
++ K+N + A+GT + P S+ V P + + E D K+ + L
Sbjct: 292 KNTFQSKINQEELASGTPPARFPKAPSKLTVGGPWGQSQEKEKGDKNSATPKQKPLPPLF 351
Query: 342 NRVPPTLNGHLNPTSE-----KSAAGLPLPPAAAAIPT---PPPLPSTYLPISHPPQIVN 393
PP + P + K+++G + T PPP PS P S PP +
Sbjct: 352 TLGPPPPKPNRPPNVDLTKFHKTSSGNSTSKGQTSYSTTSLPPPPPSH--PASQPP-LPA 408
Query: 394 SNSNSPSTPEGRGTQDLPVDSFSQNDSIYEDQQDKYTSRTSLETLPPGSVLLKCPKPMEE 453
S+ + P P P F + ED QD T L + E
Sbjct: 409 SHPSQPPVPSLPPRNIKP--PFDLKSPVNEDNQDGVTHSDGAGNLDE--------EQDSE 458
Query: 454 NHSMSHKKSKKKSKKHKEKDQIKKHDIETIEEKEEDLKREEEIAK 498
+ ++ K+ +K +EK++ K+ ++E E+KE++ K+E+EI K
Sbjct: 459 GETYEDIEASKEREKKREKEEKKRLELEKKEQKEKE-KKEQEIKK 502
>gi|42476118 FYN binding protein (FYB-120/130) isoform 1 [Homo
sapiens]
Length = 829
Score = 45.4 bits (106), Expect = 2e-04
Identities = 54/225 (24%), Positives = 92/225 (40%), Gaps = 24/225 (10%)
Query: 284 ESVLSRKLNPSQNAAGTSRSESPVCSSRDAVSSPQKRLLDSEFIDP--LMNKKARISHLT 341
++ K+N + A+GT + P S+ V P + + E D K+ + L
Sbjct: 292 KNTFQSKINQEELASGTPPARFPKAPSKLTVGGPWGQSQEKEKGDKNSATPKQKPLPPLF 351
Query: 342 NRVPPTLNGHLNPTSE-----KSAAGLPLPPAAAAIPT---PPPLPSTYLPISHPPQIVN 393
PP + P + K+++G + T PPP PS P S PP +
Sbjct: 352 TLGPPPPKPNRPPNVDLTKFHKTSSGNSTSKGQTSYSTTSLPPPPPSH--PASQPP-LPA 408
Query: 394 SNSNSPSTPEGRGTQDLPVDSFSQNDSIYEDQQDKYTSRTSLETLPPGSVLLKCPKPMEE 453
S+ + P P P F + ED QD T L + E
Sbjct: 409 SHPSQPPVPSLPPRNIKP--PFDLKSPVNEDNQDGVTHSDGAGNLDE--------EQDSE 458
Query: 454 NHSMSHKKSKKKSKKHKEKDQIKKHDIETIEEKEEDLKREEEIAK 498
+ ++ K+ +K +EK++ K+ ++E E+KE++ K+E+EI K
Sbjct: 459 GETYEDIEASKEREKKREKEEKKRLELEKKEQKEKE-KKEQEIKK 502
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 43.1 bits (100), Expect = 8e-04
Identities = 46/172 (26%), Positives = 79/172 (45%), Gaps = 24/172 (13%)
Query: 345 PPTLNGHLNPTSEKSAAGLPLPPAA-AAIPTPPPLPSTYLPISHPP----QIVNSNSNSP 399
PP G P S G PLPPA + +P+ PP P+ P S PP QI +
Sbjct: 678 PPAGPGTFKPGSPTVGPG-PLPPAGPSGLPSLPPPPAA--PASGPPLSATQIKQEPAEEY 734
Query: 400 STPEG-----RGTQDLP----VDSFSQNDSIYEDQQDK---YTSRTSLETLP-PGSVLLK 446
TPE R P V S + + + D+ +R+ L +P GS L K
Sbjct: 735 ETPESPVPPARSPSPPPKVVDVPSHASQSARFNKHLDRGFNSCARSDLYFVPLEGSKLAK 794
Query: 447 CPKPMEENHSMSHKKSKKKSKKHKEKDQIKKHDIETIEEKEEDLKREEEIAK 498
+ E +++++++++ KE+++ ++ + E EKE +L+R ++A+
Sbjct: 795 KRADLVEK---VRREAEQRAREEKEREREREREKEREREKERELERSVKLAQ 843
Score = 30.4 bits (67), Expect = 5.2
Identities = 33/120 (27%), Positives = 44/120 (36%), Gaps = 16/120 (13%)
Query: 354 PTSEKSAAGLPLPPAAAAIP-TPPPLPSTYLPISHPPQIVNSNSNSPSTPEGRGTQDLPV 412
PT+ LP P A P P LP PP + +N+ ++P G G Q LP
Sbjct: 276 PTTPVGGGNLPSAPPPANFPHVTPNLP--------PPPALRPLNNASASPPGLGAQPLPG 327
Query: 413 DSFSQN------DSIYEDQQDKYTSRTSLETLPPGSVLLKCPKPMEENHSMSHKKSKKKS 466
S + + + T S +LPP S P PM +S S S S
Sbjct: 328 HLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAP-PMRFPYSSSSSSSAAAS 386
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 43.1 bits (100), Expect = 8e-04
Identities = 46/172 (26%), Positives = 79/172 (45%), Gaps = 24/172 (13%)
Query: 345 PPTLNGHLNPTSEKSAAGLPLPPAA-AAIPTPPPLPSTYLPISHPP----QIVNSNSNSP 399
PP G P S G PLPPA + +P+ PP P+ P S PP QI +
Sbjct: 678 PPAGPGTFKPGSPTVGPG-PLPPAGPSGLPSLPPPPAA--PASGPPLSATQIKQEPAEEY 734
Query: 400 STPEG-----RGTQDLP----VDSFSQNDSIYEDQQDK---YTSRTSLETLP-PGSVLLK 446
TPE R P V S + + + D+ +R+ L +P GS L K
Sbjct: 735 ETPESPVPPARSPSPPPKVVDVPSHASQSARFNKHLDRGFNSCARSDLYFVPLEGSKLAK 794
Query: 447 CPKPMEENHSMSHKKSKKKSKKHKEKDQIKKHDIETIEEKEEDLKREEEIAK 498
+ E +++++++++ KE+++ ++ + E EKE +L+R ++A+
Sbjct: 795 KRADLVEK---VRREAEQRAREEKEREREREREKEREREKERELERSVKLAQ 843
Score = 30.4 bits (67), Expect = 5.2
Identities = 33/120 (27%), Positives = 44/120 (36%), Gaps = 16/120 (13%)
Query: 354 PTSEKSAAGLPLPPAAAAIP-TPPPLPSTYLPISHPPQIVNSNSNSPSTPEGRGTQDLPV 412
PT+ LP P A P P LP PP + +N+ ++P G G Q LP
Sbjct: 276 PTTPVGGGNLPSAPPPANFPHVTPNLP--------PPPALRPLNNASASPPGLGAQPLPG 327
Query: 413 DSFSQN------DSIYEDQQDKYTSRTSLETLPPGSVLLKCPKPMEENHSMSHKKSKKKS 466
S + + + T S +LPP S P PM +S S S S
Sbjct: 328 HLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAP-PMRFPYSSSSSSSAAAS 386
>gi|95147555 microtubule-associated protein 1A [Homo sapiens]
Length = 2803
Score = 42.0 bits (97), Expect = 0.002
Identities = 69/368 (18%), Positives = 142/368 (38%), Gaps = 50/368 (13%)
Query: 136 ERMTQAEEESRNRSTKVIKPGGPYVGKRVQIRKAPQAVSDTVPERKRSTPMNPANTIRKT 195
+ + + E++++ S K P P +RV+ S+ + KR +
Sbjct: 354 KELAKTEKKAKESSEK--PPEKPAKPERVKTES-----SEALKAEKRKLIKDKVGKKHLK 406
Query: 196 HSSSTISQRPYRDRVIHLLALKAYKKPELLARLQKDGVNQKDKNSLGAILQQVANLNSKD 255
S + ++ +++ K KK E +KD ++ + L++++ + K
Sbjct: 407 EKISKLEEKKDKEKKEIKKERKELKKDEGRKEEKKDAKKEEKRKDTKPELKKISKPDLKP 466
Query: 256 LSYTLKDYVFKELQRDWPGYSEIDR-RSLESVLSRKLNPSQNAAGTSRSESPVCSSRD-- 312
+ ++ ++K PG +IDR R++ P A P S
Sbjct: 467 FTPEVRKTLYKAKV---PGRVKIDRSRAIRGEKELSSEPQTPPAQKGTVPLPTISGHREL 523
Query: 313 AVSSPQKRLLDSEFIDPLMNKKARISHLTNRVPPTLNGHLNP--TSEKSAAGLPLPPAAA 370
+SSP+ D E + K+ + L + L P T+E+ PP+ A
Sbjct: 524 VLSSPEDLTQDFEEM-----KREERALLAEQRDTGLGDKPFPLDTAEEG------PPSTA 572
Query: 371 AIPTPPPLPSTYLPISHPPQIVNSNSNSPSTPEGRGTQDLPVDSFSQNDSIYEDQQDKYT 430
TPP +P + ++ P PE +G++D +DS ++ E+++D +
Sbjct: 573 IQGTPPSVPG----LGQEEHVMKEKELVPEVPEEQGSKDRGLDSGAET----EEEKDTWE 624
Query: 431 SRTSLETLPPGSVLLKCPKPMEENHSMSHKKSKKKSKKHKEKDQIKKHDIETIEEKEEDL 490
+ K E +++++S+ ++D I+K ++E +EE
Sbjct: 625 EK----------------KQREAERLPDRTEAREESEPEVKEDVIEKAELEEMEEVHPSD 668
Query: 491 KREEEIAK 498
+ EE+ K
Sbjct: 669 EEEEDATK 676
Score = 34.7 bits (78), Expect = 0.28
Identities = 54/273 (19%), Positives = 109/273 (39%), Gaps = 15/273 (5%)
Query: 350 GHLNPTSEKS--AAGLPLPPAAAAIPTPPPLPSTYLPISHPPQIVNSNSNSP------ST 401
GHL + S A + +P AA +PP +T + + SP ST
Sbjct: 1238 GHLMQAEDTSHHTAPMSVPEPHAATASPPTDGTTRYSAQTDITDDSLDRKSPASSFSHST 1297
Query: 402 PEGRGTQDLPVDSFSQNDSIYEDQQDKYTSRTSLETLPPGSVLLKCPKPMEENHSMSHKK 461
P G G LP S ++ I S SL PG L E+ +
Sbjct: 1298 PSGNGKY-LPGAITSPDEHILTPDSSFSKSPESL----PGPALEDIAIKWEDKVPGLKDR 1352
Query: 462 SKKKSKKHKEKDQIKKHDIETIEEKEEDLKREEEIAKLNNSSPNSSGGVK-EDCTASMEP 520
+ ++ K+ + KD++ + +T+E KE ++ I + + + + VK +D +
Sbjct: 1353 TSEQKKEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQKG 1412
Query: 521 SAIELPDYLIKYIAIVSYEQRQNYKDDFNAEYDEYRALHARMETVARRFIKLDAQRKRLS 580
+E D ++ + ++ ++ A + + + + + ++ L+ + K L
Sbjct: 1413 RDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALE 1472
Query: 581 PGSKEYQNVHEEVLQEYQKIKQSSPNYHEEKYR 613
P K+ + + VL++ +KI + ++K R
Sbjct: 1473 PKDKDLEQ-KDRVLEQKEKIPEEKDKALDQKVR 1504
Score = 32.0 bits (71), Expect = 1.8
Identities = 32/169 (18%), Positives = 69/169 (40%), Gaps = 9/169 (5%)
Query: 449 KPMEENHSMSHKKSK---KKSKKHKEKDQIKKHDIETIEEKEEDLKREEEIAKLNNSSPN 505
K +EE +K K +K K ++KD + + +E K++DL++++ + + P
Sbjct: 1434 KDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPE 1493
Query: 506 SSGGVKEDCTASMEPSAIELPDYLIKYIAIVSYEQRQNYKDD-FNAEYDEYRALHARMET 564
+ S+E A P+ + + EQ + A+ + + + +
Sbjct: 1494 EKDKALDQKVRSVEHKA---PEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQA 1550
Query: 565 VARRFIKLDAQRKRLSPGSKEYQNVHEEVLQE--YQKIKQSSPNYHEEK 611
+ +++ L + + L + + H+ QE Q+ K P EEK
Sbjct: 1551 LEQKYWALGQKDEALEQNIQALEENHQTQEQESLVQEDKTRKPKMLEEK 1599
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 42.0 bits (97), Expect = 0.002
Identities = 51/208 (24%), Positives = 72/208 (34%), Gaps = 47/208 (22%)
Query: 273 PGYSEIDRRSLESVLSRKLNPSQNAAGTSRSESPVCSSRDAVSSPQKRLLDSEFIDPL-- 330
P S + RS + +P A TS S PV R A SSPQ+R S P+
Sbjct: 666 PSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPV--RRGASSSPQRRQSPSPSTRPIRR 723
Query: 331 MNKKARISHLTNRVPPTLNGHLNPTSEKSAAGLPLPPAAAAIPTPPPLPSTYLPISHPPQ 390
+++ + P+ +S +S +G P PAA P PP + P
Sbjct: 724 VSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSP-EPAAKKPPAPPSPVQSQSP------ 776
Query: 391 IVNSNSNSPSTPEGRGTQDLPVDSFSQNDSIYEDQQDKYTSRTSLETLPPGSVLLKCPKP 450
S + SP+ P + P S +N
Sbjct: 777 ---STNWSPAVPVKKAKSPTPSPSPPRNS------------------------------- 802
Query: 451 MEENHSMSHKKSKKKSKKHKEKDQIKKH 478
+ KK KKK KKHK+ + KKH
Sbjct: 803 --DQEGGGKKKKKKKDKKHKKDKKHKKH 828
Score = 38.9 bits (89), Expect = 0.015
Identities = 72/346 (20%), Positives = 117/346 (33%), Gaps = 55/346 (15%)
Query: 139 TQAEEESRNRSTKVIKPGGPYVGKRVQIRKAPQAVSDTVPERKRSTPMNPANTIRKTHSS 198
+ + SR+RS P R R +P A P R+R P PA KT S
Sbjct: 359 SSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSAS----PPRRRHRPSPPATPPPKTRHS 414
Query: 199 ST-----------ISQRPYRD--RVIHLLALKAYKKPELLARLQKDGVNQKDKNSLGAIL 245
T +S P R +V + + P + +K +++ +++ G
Sbjct: 415 PTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGG--- 471
Query: 246 QQVANLNSKDLSYTLKDYVFKELQRDWPGYSEIDRRSLESVLSRKLNPSQNAAGTSRSES 305
+ + D + Y + Q S S E ++ + G R S
Sbjct: 472 ----KMAAADSVQQRRQYRRQNQQSSSDSGSS---SSSEDERPKRSHVKNGEVGRRRRHS 524
Query: 306 PVCSSRDAVSSPQKRLLDSEFIDPLMNKKARISHLTNRVPPTLNGHLNPTSEKSAAGLPL 365
P SR A SP+KR ++ + + R + P +P P
Sbjct: 525 P---SRSASPSPRKRQKET-------SPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPT 574
Query: 366 PPAAAAIPTPPPLPSTYLPISHPPQIVNSNSNSPSTPEGRGTQDLPVDSFSQNDSIYEDQ 425
PP P+PPP + P + P I SPS P R T P
Sbjct: 575 PPPRRRTPSPPPRRRSPSPRRYSPPI--QRRYSPSPPPKRRTASPPPP------------ 620
Query: 426 QDKYTSRTSLETLPPGSVLLKCPKPMEENHSMSHKKSKKKSKKHKE 471
R + + PP + P P + + ++ ++S S KH++
Sbjct: 621 ----PKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRK 662
>gi|126090663 zinc finger homeodomain 4 [Homo sapiens]
Length = 3571
Score = 41.6 bits (96), Expect = 0.002
Identities = 41/142 (28%), Positives = 64/142 (45%), Gaps = 14/142 (9%)
Query: 359 SAAGLPLPPAAAAIPTPPP--LPSTYLPISHPPQIVNSNSNSPSTPEGRGTQDLPVDSFS 416
S G+ LP A +P PP LP P S P NSN+ TP G G P + S
Sbjct: 3043 SLHGISLPTAYPGLPGLPPVLLPGMNGPSSLPGFPQNSNT---LTPPGAGMLGFPTSATS 3099
Query: 417 QNDSIYEDQQDKYTSRTSLETLPPGSVLLKCPKPMEENHSMSHKKSKKKSKKHKEKDQIK 476
K L+T PP P P + S+S +++++++K+ EK Q K
Sbjct: 3100 SPALSLSSAPTK----PLLQTPPPPPP----PPPPPPSSSLSGQQTEQQNKE-SEKKQTK 3150
Query: 477 KHDIETIEEKEEDLKREEEIAK 498
+ ++ I+E+E + + E+ K
Sbjct: 3151 PNKVKKIKEEELEATKPEKHPK 3172
Score = 32.0 bits (71), Expect = 1.8
Identities = 17/51 (33%), Positives = 21/51 (41%)
Query: 352 LNPTSEKSAAGLPLPPAAAAIPTPPPLPSTYLPISHPPQIVNSNSNSPSTP 402
L P S S P PP +P PP PS+ P+ P + P TP
Sbjct: 1947 LYPISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTP 1997
Score = 30.4 bits (67), Expect = 5.2
Identities = 16/39 (41%), Positives = 17/39 (43%)
Query: 353 NPTSEKSAAGLPLPPAAAAIPTPPPLPSTYLPISHPPQI 391
N S A P PP P PPP P P S PPQ+
Sbjct: 1984 NTVSTPLQAPPPTPPPPPPPPPPPPPPPPPPPPSAPPQV 2022
>gi|7662244 DAZ interacting protein 3, zinc finger [Homo sapiens]
Length = 1208
Score = 41.6 bits (96), Expect = 0.002
Identities = 46/206 (22%), Positives = 92/206 (44%), Gaps = 28/206 (13%)
Query: 449 KPMEENHSMSHKKSKKKSKKHKEKDQIKKHDIETIEEKEEDLKREEEIAKLNNSSPNS-S 507
K ++E S KK K K+KK+K+ K+ + + EKEE L++E+ ++P+S S
Sbjct: 650 KDLQEVKSKQRKKKKTKNKKNKDS---KEDQVPYVVEKEEQLRKEQ-------ANPHSVS 699
Query: 508 GGVKEDCTASMEPSAIELPDYLIKYIAI-----------VSYEQRQNYKDDFNAEYDEYR 556
+K+D + E SA+E Y + + I V+ + + K+ + Y+
Sbjct: 700 RLIKDDASDVQEDSAMEDKFYSLDELHILDMIEQGSAGKVTTDYGETEKERLARQRQLYK 759
Query: 557 ALHARMETVARRF----IKLDAQRKRLSPGSKEYQNVHEEVLQEYQKIKQSSPNYHEEKY 612
LH + E R+ + + ++ K +++++V K+ + H +
Sbjct: 760 -LHYQCEDFKRQLRTVTFRWQENQMQIKKKDKIIASLNQQVAFGINKVSKLQRQIHAKDN 818
Query: 613 RCEYLHNKLAHIKRLIGEFDQQQAES 638
+ L +L+ +KR E ++ ES
Sbjct: 819 EIKNLKEQLS-MKRSQWEMEKHNLES 843
>gi|120953251 neuron navigator 3 [Homo sapiens]
Length = 2363
Score = 40.8 bits (94), Expect = 0.004
Identities = 62/274 (22%), Positives = 105/274 (38%), Gaps = 31/274 (11%)
Query: 274 GYSEIDRRSLESVLSRKLNPSQNAAGTSRSESPVCSSRDAVSS-----------PQKRLL 322
G S ++RRS K P A G + S S V+ P +
Sbjct: 265 GASNLNRRSQSFNSIDKNKPPNYANGNEKDSSKGPQSSSGVNGNVQPPSTAGQPPASAIP 324
Query: 323 DSEFIDPLMNKKARISHLTNRVPPTLNGHLNPTSEKSAAGLPLPPAAAAIPTPPPLPSTY 382
P +K + H T+ TS ++ PP + + T P +
Sbjct: 325 SPSASKPWRSKSMNVKHSATSTMLTVKQSSTATSPTPSSDRLKPPVSEGVKTAPSGQKSM 384
Query: 383 LPISHPPQIVNSNSN-SPSTPEGRGTQD--LPVDSFSQNDSIYEDQQDKYTSRTSLETLP 439
L ++VN+ + P P G D D+FS++ + E S S + P
Sbjct: 385 L---EKFKLVNARTALRPPQPPSSGPSDGGKDDDAFSESGEM-EGFNSGLNSGGSTNSSP 440
Query: 440 PGSVLLKCPKPMEENHSMSHKKS--KKKSKKHKEKDQIKKHDIETIEEKEEDL-----KR 492
S L PK +N +S+KKS + K K+ K +D+ K + ++E+++ + K+
Sbjct: 441 KVSPKLAPPKAGSKN--LSNKKSLLQPKEKEEKNRDKNKVCTEKPVKEEKDQVTEMAPKK 498
Query: 493 EEEIAKLNNSSPNSSGGVKEDCTASMEPSAIELP 526
+IA L ++ KE S+ PS+ +P
Sbjct: 499 TSKIASLIPKGSKTTAAKKE----SLIPSSSGIP 528
>gi|189011568 adenomatous polyposis coli [Homo sapiens]
Length = 2843
Score = 40.0 bits (92), Expect = 0.007
Identities = 66/295 (22%), Positives = 117/295 (39%), Gaps = 35/295 (11%)
Query: 276 SEIDRRSLESVLSRKLNPSQNAAGTSRS-------ESPVCSSR-DAVSSPQKRLLDSEFI 327
SE R S +PS++ A T +S E+P+ SR +VSS +
Sbjct: 1344 SESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSS----------L 1393
Query: 328 DPLMNKKARISHLTNRVPPTLNGHLNPTSEKSAAGLPLPPAAAAIPTPPPLPS---TYLP 384
D ++ S + ++G ++P+ + G +PP+ + P PPP + +P
Sbjct: 1394 DSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPPPPPQTAQTKREVP 1453
Query: 385 ISHPPQIVNSNSNSPSTPEGRGTQDLPV--DSFSQNDSIYEDQQDKYTSRTSLETLP--- 439
+ P S Q + V D+ + E D ++ +SL L
Sbjct: 1454 KNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLHFATESTPDGFSCSSSLSALSLDE 1513
Query: 440 ---PGSVLLKCPKPMEENHSMSHKKSK--KKSKKHKEKDQIKKHDIE---TIEEKEEDLK 491
V L+ P++EN + + +S+ K+S +++EK+ K D E + ++D++
Sbjct: 1514 PFIQKDVELRIMPPVQENDNGNETESEQPKESNENQEKEAEKTIDSEKDLLDDSDDDDIE 1573
Query: 492 REEEIAKLNNSSPNSSGGVKEDCTAS-MEPSAIELPDYLIKYIAIVSYEQRQNYK 545
EE + +S K TAS + P P L Y + S + Q K
Sbjct: 1574 ILEECIISAMPTKSSRKAKKPAQTASKLPPPVARKPSQLPVYKLLPSQNRLQPQK 1628
>gi|189011566 adenomatous polyposis coli [Homo sapiens]
Length = 2843
Score = 40.0 bits (92), Expect = 0.007
Identities = 66/295 (22%), Positives = 117/295 (39%), Gaps = 35/295 (11%)
Query: 276 SEIDRRSLESVLSRKLNPSQNAAGTSRS-------ESPVCSSR-DAVSSPQKRLLDSEFI 327
SE R S +PS++ A T +S E+P+ SR +VSS +
Sbjct: 1344 SESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSS----------L 1393
Query: 328 DPLMNKKARISHLTNRVPPTLNGHLNPTSEKSAAGLPLPPAAAAIPTPPPLPS---TYLP 384
D ++ S + ++G ++P+ + G +PP+ + P PPP + +P
Sbjct: 1394 DSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPPPPPQTAQTKREVP 1453
Query: 385 ISHPPQIVNSNSNSPSTPEGRGTQDLPV--DSFSQNDSIYEDQQDKYTSRTSLETLP--- 439
+ P S Q + V D+ + E D ++ +SL L
Sbjct: 1454 KNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLHFATESTPDGFSCSSSLSALSLDE 1513
Query: 440 ---PGSVLLKCPKPMEENHSMSHKKSK--KKSKKHKEKDQIKKHDIE---TIEEKEEDLK 491
V L+ P++EN + + +S+ K+S +++EK+ K D E + ++D++
Sbjct: 1514 PFIQKDVELRIMPPVQENDNGNETESEQPKESNENQEKEAEKTIDSEKDLLDDSDDDDIE 1573
Query: 492 REEEIAKLNNSSPNSSGGVKEDCTAS-MEPSAIELPDYLIKYIAIVSYEQRQNYK 545
EE + +S K TAS + P P L Y + S + Q K
Sbjct: 1574 ILEECIISAMPTKSSRKAKKPAQTASKLPPPVARKPSQLPVYKLLPSQNRLQPQK 1628
>gi|53759122 adenomatous polyposis coli [Homo sapiens]
Length = 2843
Score = 40.0 bits (92), Expect = 0.007
Identities = 66/295 (22%), Positives = 117/295 (39%), Gaps = 35/295 (11%)
Query: 276 SEIDRRSLESVLSRKLNPSQNAAGTSRS-------ESPVCSSR-DAVSSPQKRLLDSEFI 327
SE R S +PS++ A T +S E+P+ SR +VSS +
Sbjct: 1344 SESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSS----------L 1393
Query: 328 DPLMNKKARISHLTNRVPPTLNGHLNPTSEKSAAGLPLPPAAAAIPTPPPLPS---TYLP 384
D ++ S + ++G ++P+ + G +PP+ + P PPP + +P
Sbjct: 1394 DSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPPPPPQTAQTKREVP 1453
Query: 385 ISHPPQIVNSNSNSPSTPEGRGTQDLPV--DSFSQNDSIYEDQQDKYTSRTSLETLP--- 439
+ P S Q + V D+ + E D ++ +SL L
Sbjct: 1454 KNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLHFATESTPDGFSCSSSLSALSLDE 1513
Query: 440 ---PGSVLLKCPKPMEENHSMSHKKSK--KKSKKHKEKDQIKKHDIE---TIEEKEEDLK 491
V L+ P++EN + + +S+ K+S +++EK+ K D E + ++D++
Sbjct: 1514 PFIQKDVELRIMPPVQENDNGNETESEQPKESNENQEKEAEKTIDSEKDLLDDSDDDDIE 1573
Query: 492 REEEIAKLNNSSPNSSGGVKEDCTAS-MEPSAIELPDYLIKYIAIVSYEQRQNYK 545
EE + +S K TAS + P P L Y + S + Q K
Sbjct: 1574 ILEECIISAMPTKSSRKAKKPAQTASKLPPPVARKPSQLPVYKLLPSQNRLQPQK 1628
>gi|125656165 THO complex 2 [Homo sapiens]
Length = 1593
Score = 40.0 bits (92), Expect = 0.007
Identities = 38/151 (25%), Positives = 63/151 (41%), Gaps = 26/151 (17%)
Query: 395 NSNSPSTPEGRGTQDLPVDSFS----QNDSIYEDQQDKYTSRTSLETLPPGSVLLKC--P 448
N S +TP+G + + + +ND +++K + T P VL K
Sbjct: 1242 NKASSTTPKGNSSNGNSGSNSNKAVKENDKEKGKEKEKEKKEKTPATTPEARVLGKDGKE 1301
Query: 449 KPMEENHSMSHK---------KSKKKSKKHKEKDQIKKHDIETI-----------EEKEE 488
KP EE + K KS K+ +K K++++ K +T E+E+
Sbjct: 1302 KPKEERPNKDEKARETKERTPKSDKEKEKFKKEEKAKDEKFKTTVPNAESKSTQEREREK 1361
Query: 489 DLKREEEIAKLNNSSPNSSGGVKEDCTASME 519
+ RE +IAK S N GG K + S++
Sbjct: 1362 EPSRERDIAKEMKSKENVKGGEKTPVSGSLK 1392
>gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens]
Length = 1303
Score = 40.0 bits (92), Expect = 0.007
Identities = 48/212 (22%), Positives = 91/212 (42%), Gaps = 23/212 (10%)
Query: 358 KSAAGLPLPPAAAAIPTP-PPLPSTYLPISHPPQIVNSNSNSPSTPEGRGTQDLPVDSFS 416
++A G P PP + + P P PP PST P PP ++ +P R LP+
Sbjct: 2 EAAPGTPPPPPSESPPPPSPPPPSTPSP---PPCSPDARPATPHLLHHR----LPLPDDR 54
Query: 417 QNDSIYEDQQDKYTSRTSLETLPPGSVLLKCPKPMEENHS-----MSHKKSKKKSKKHKE 471
++ + E + + + + +T G + E++HS SH++ K+K KK +E
Sbjct: 55 EDGELEEGELEDDGAEETQDT--SGGPERSRKEKGEKHHSDSDEEKSHRRLKRKRKKERE 112
Query: 472 KDQIKKHDIETIEEKEEDLKREE--EIAKLNNSSPNSSGGVK-EDCTASMEPSAIELPDY 528
K++ + + K ++ + + ++ SP+ G K + + PS + P
Sbjct: 113 KEKRRSKKRRKSKHKRHASSSDDFSDFSDDSDFSPSEKGHRKYREYSPPYAPSHQQYPPS 172
Query: 529 LIKYIAIVSYEQRQN-----YKDDFNAEYDEY 555
+ +Y + + Y+D N +Y EY
Sbjct: 173 HATPLPKKAYSKMDSKSYGMYEDYENEQYGEY 204
>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
Length = 1220
Score = 39.7 bits (91), Expect = 0.009
Identities = 31/136 (22%), Positives = 62/136 (45%), Gaps = 8/136 (5%)
Query: 368 AAAAIPTPPPLPSTYLPISHPP-------QIVNSNSNSPSTPEGRGTQDLPVDSFSQNDS 420
A + P PP LP Y+P S +++S S PE +D +
Sbjct: 289 AMSGQPLPPVLPPEYIPPSFRRVRSGSGISVISSTSVDQRLPEEPVLEDEQQQLEKKLPV 348
Query: 421 IYEDQQDKYTSRTSLETLPPGSVLLKCP-KPMEENHSMSHKKSKKKSKKHKEKDQIKKHD 479
+ED++ + R +LE LL+ K E + + ++K ++ +E+++ ++ +
Sbjct: 349 TFEDKKRENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLE 408
Query: 480 IETIEEKEEDLKREEE 495
+E EK+ +L+R+ E
Sbjct: 409 LEKQLEKQRELERQRE 424
>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
Length = 1721
Score = 39.7 bits (91), Expect = 0.009
Identities = 31/136 (22%), Positives = 62/136 (45%), Gaps = 8/136 (5%)
Query: 368 AAAAIPTPPPLPSTYLPISHPP-------QIVNSNSNSPSTPEGRGTQDLPVDSFSQNDS 420
A + P PP LP Y+P S +++S S PE +D +
Sbjct: 289 AMSGQPLPPVLPPEYIPPSFRRVRSGSGISVISSTSVDQRLPEEPVLEDEQQQLEKKLPV 348
Query: 421 IYEDQQDKYTSRTSLETLPPGSVLLKCP-KPMEENHSMSHKKSKKKSKKHKEKDQIKKHD 479
+ED++ + R +LE LL+ K E + + ++K ++ +E+++ ++ +
Sbjct: 349 TFEDKKRENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLE 408
Query: 480 IETIEEKEEDLKREEE 495
+E EK+ +L+R+ E
Sbjct: 409 LEKQLEKQRELERQRE 424
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 39.7 bits (91), Expect = 0.009
Identities = 24/69 (34%), Positives = 30/69 (43%), Gaps = 4/69 (5%)
Query: 345 PPTLNGHLNPTSEKSAAGLPLPP--AAAAIPTPPPLPSTYLPISHPPQIVNSNSNSPSTP 402
PP + P AG+P PP AAIP PPPLP +P+ PP + + P
Sbjct: 924 PPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPL--PPPLPGAGIPPPPPL 981
Query: 403 EGRGTQDLP 411
G G P
Sbjct: 982 PGAGIPPPP 990
Score = 39.7 bits (91), Expect = 0.009
Identities = 24/69 (34%), Positives = 29/69 (42%), Gaps = 4/69 (5%)
Query: 345 PPTLNGHLNPTSEKSAAGLPLPP--AAAAIPTPPPLPSTYLPISHPPQIVNSNSNSPSTP 402
PP + P AG+PLPP A IP PPPLP +P PP + + P
Sbjct: 946 PPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIP--PPPPLPGAGIPPPPPL 1003
Query: 403 EGRGTQDLP 411
G G P
Sbjct: 1004 PGAGIPPPP 1012
Score = 37.0 bits (84), Expect = 0.056
Identities = 23/69 (33%), Positives = 28/69 (40%), Gaps = 4/69 (5%)
Query: 345 PPTLNGHLNPTSEKSAAGLPLPP--AAAAIPTPPPLPSTYLPISHPPQIVNSNSNSPSTP 402
PP + P AG+P PP A IP PPPLP +P PP + + P
Sbjct: 968 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP--PPPPLPGAGIPPPPPL 1025
Query: 403 EGRGTQDLP 411
G G P
Sbjct: 1026 PGAGIPPPP 1034
Score = 37.0 bits (84), Expect = 0.056
Identities = 23/69 (33%), Positives = 28/69 (40%), Gaps = 4/69 (5%)
Query: 345 PPTLNGHLNPTSEKSAAGLPLPP--AAAAIPTPPPLPSTYLPISHPPQIVNSNSNSPSTP 402
PP + P AG+P PP A IP PPPLP +P PP + + P
Sbjct: 979 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP--PPPPLPGAGIPPPPPL 1036
Query: 403 EGRGTQDLP 411
G G P
Sbjct: 1037 PGAGIPPPP 1045
Score = 37.0 bits (84), Expect = 0.056
Identities = 23/69 (33%), Positives = 28/69 (40%), Gaps = 4/69 (5%)
Query: 345 PPTLNGHLNPTSEKSAAGLPLPP--AAAAIPTPPPLPSTYLPISHPPQIVNSNSNSPSTP 402
PP + P AG+P PP A IP PPPLP +P PP + + P
Sbjct: 990 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP--PPPPLPGAGIPPPPPL 1047
Query: 403 EGRGTQDLP 411
G G P
Sbjct: 1048 PGAGIPPPP 1056
Score = 37.0 bits (84), Expect = 0.056
Identities = 23/69 (33%), Positives = 28/69 (40%), Gaps = 4/69 (5%)
Query: 345 PPTLNGHLNPTSEKSAAGLPLPP--AAAAIPTPPPLPSTYLPISHPPQIVNSNSNSPSTP 402
PP + P AG+P PP A IP PPPLP +P PP + + P
Sbjct: 1001 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP--PPPPLPGAGIPPPPPL 1058
Query: 403 EGRGTQDLP 411
G G P
Sbjct: 1059 PGAGIPPPP 1067
Score = 37.0 bits (84), Expect = 0.056
Identities = 23/69 (33%), Positives = 28/69 (40%), Gaps = 4/69 (5%)
Query: 345 PPTLNGHLNPTSEKSAAGLPLPP--AAAAIPTPPPLPSTYLPISHPPQIVNSNSNSPSTP 402
PP + P AG+P PP A IP PPPLP +P PP + + P
Sbjct: 1012 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP--PPPPLPGAGIPPPPPL 1069
Query: 403 EGRGTQDLP 411
G G P
Sbjct: 1070 PGAGIPPPP 1078
Score = 37.0 bits (84), Expect = 0.056
Identities = 23/69 (33%), Positives = 28/69 (40%), Gaps = 4/69 (5%)
Query: 345 PPTLNGHLNPTSEKSAAGLPLPP--AAAAIPTPPPLPSTYLPISHPPQIVNSNSNSPSTP 402
PP + P AG+P PP A IP PPPLP +P PP + + P
Sbjct: 1023 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP--PPPPLPGAGIPPPPPL 1080
Query: 403 EGRGTQDLP 411
G G P
Sbjct: 1081 PGAGIPPPP 1089
Score = 37.0 bits (84), Expect = 0.056
Identities = 23/69 (33%), Positives = 28/69 (40%), Gaps = 4/69 (5%)
Query: 345 PPTLNGHLNPTSEKSAAGLPLPP--AAAAIPTPPPLPSTYLPISHPPQIVNSNSNSPSTP 402
PP + P AG+P PP A IP PPPLP +P PP + + P
Sbjct: 1034 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP--PPPPLPGAGIPPPPPL 1091
Query: 403 EGRGTQDLP 411
G G P
Sbjct: 1092 PGAGIPPPP 1100
Score = 37.0 bits (84), Expect = 0.056
Identities = 23/69 (33%), Positives = 28/69 (40%), Gaps = 4/69 (5%)
Query: 345 PPTLNGHLNPTSEKSAAGLPLPP--AAAAIPTPPPLPSTYLPISHPPQIVNSNSNSPSTP 402
PP + P AG+P PP A IP PPPLP +P PP + + P
Sbjct: 1067 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIP--PPPPLPGAGIPPPPPL 1124
Query: 403 EGRGTQDLP 411
G G P
Sbjct: 1125 PGAGIPPPP 1133
Score = 36.6 bits (83), Expect = 0.073
Identities = 23/69 (33%), Positives = 28/69 (40%), Gaps = 4/69 (5%)
Query: 345 PPTLNGHLNPTSEKSAAGLPLPP--AAAAIPTPPPLPSTYLPISHPPQIVNSNSNSPSTP 402
PP + P AG+P PP A IP PPPLP +P PP + + P
Sbjct: 1111 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIP--PPPPLPGAGIPPPPPL 1168
Query: 403 EGRGTQDLP 411
G G P
Sbjct: 1169 PGAGIPPPP 1177
Score = 36.6 bits (83), Expect = 0.073
Identities = 44/180 (24%), Positives = 66/180 (36%), Gaps = 37/180 (20%)
Query: 345 PPTLNG-HLNPTSEKSAAGLPLPPA--AAAIPTPPPLPS--------------------- 380
PP L G + P G+P PP A IP PPPLP
Sbjct: 1176 PPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPP 1235
Query: 381 TYLPISHPPQIVNSNSNSPSTPEGRGTQDLPVDSFSQNDSIYEDQQDKYTSRTSLETLPP 440
LP+S PP + S++ TP+ G P+ S + QDK + + +E P
Sbjct: 1236 PLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLPSGLFGLGM---NQDKGSRKQPIEPCRP 1292
Query: 441 GSVLLKCPKPMEENHSMSHKKSKKKSK---KHKEKDQIKKHDIETIEEKEEDLKREEEIA 497
KP+ H K + + E+ I H+ E + K +R++ I+
Sbjct: 1293 -------MKPLYWTRIQLHSKRDSSTSLIWEKIEEPSIDCHEFEELFSKTAVKERKKPIS 1345
Score = 36.2 bits (82), Expect = 0.095
Identities = 25/69 (36%), Positives = 29/69 (42%), Gaps = 4/69 (5%)
Query: 345 PPTLNGHLNPTSEKSAAG-LPLPP-AAAAIPTPPPLPSTYLPISHPPQIVNSNSNSPSTP 402
PP + P AG LPLPP A IP PPPLP +P PP + + P
Sbjct: 913 PPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIP--PPPPLPGAGIPLPPPL 970
Query: 403 EGRGTQDLP 411
G G P
Sbjct: 971 PGAGIPPPP 979
Score = 36.2 bits (82), Expect = 0.095
Identities = 23/69 (33%), Positives = 28/69 (40%), Gaps = 4/69 (5%)
Query: 345 PPTLNGHLNPTSEKSAAGLPLPP--AAAAIPTPPPLPSTYLPISHPPQIVNSNSNSPSTP 402
PP + P AG+P PP A IP PPPLP +P PP + + P
Sbjct: 1045 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP--PPPPLPGAGIPPPPPL 1102
Query: 403 EGRGTQDLP 411
G G P
Sbjct: 1103 PGVGIPPPP 1111
Score = 36.2 bits (82), Expect = 0.095
Identities = 22/69 (31%), Positives = 27/69 (39%), Gaps = 4/69 (5%)
Query: 345 PPTLNGHLNPTSEKSAAGLPLPP--AAAAIPTPPPLPSTYLPISHPPQIVNSNSNSPSTP 402
PP + P AG+P PP IP PPPLP +P PP + + P
Sbjct: 1155 PPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIP--PPPPLPGAGIPPPPPL 1212
Query: 403 EGRGTQDLP 411
G G P
Sbjct: 1213 PGMGIPPAP 1221
Score = 35.8 bits (81), Expect = 0.12
Identities = 23/69 (33%), Positives = 27/69 (39%), Gaps = 4/69 (5%)
Query: 345 PPTLNGHLNPTSEKSAAGLPLPP--AAAAIPTPPPLPSTYLPISHPPQIVNSNSNSPSTP 402
PP + P AG+P PP A IP PPPLP +P PP + P
Sbjct: 1056 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP--PPPPLPGVGIPPPPPL 1113
Query: 403 EGRGTQDLP 411
G G P
Sbjct: 1114 PGAGIPPPP 1122
Score = 35.4 bits (80), Expect = 0.16
Identities = 22/69 (31%), Positives = 27/69 (39%), Gaps = 4/69 (5%)
Query: 345 PPTLNGHLNPTSEKSAAGLPLPP--AAAAIPTPPPLPSTYLPISHPPQIVNSNSNSPSTP 402
PP + P AG+P PP IP PPPLP +P PP + + P
Sbjct: 1078 PPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIP--PPPPLPGAGIPPPPPL 1135
Query: 403 EGRGTQDLP 411
G G P
Sbjct: 1136 PGAGIPPPP 1144
Score = 35.4 bits (80), Expect = 0.16
Identities = 25/70 (35%), Positives = 29/70 (41%), Gaps = 5/70 (7%)
Query: 345 PPTLNG-HLNPTSEKSAAGLPLPP--AAAAIPTPPPLPSTYLPISHPPQIVNSNSNSPST 401
PP L G + P AG+P PP A IP PPPLP +P PP + P
Sbjct: 1099 PPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP--PPPPLPRVGIPPPPP 1156
Query: 402 PEGRGTQDLP 411
G G P
Sbjct: 1157 LPGAGIPPPP 1166
Score = 35.0 bits (79), Expect = 0.21
Identities = 22/70 (31%), Positives = 28/70 (40%), Gaps = 4/70 (5%)
Query: 344 VPPTLNGHLNPTSEKSAAGLPLPP--AAAAIPTPPPLPSTYLPISHPPQIVNSNSNSPST 401
+PP + P A +P PP A IP PPPLP +P PP + + P
Sbjct: 934 LPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIP--PPPPLPGAGIPPPPP 991
Query: 402 PEGRGTQDLP 411
G G P
Sbjct: 992 LPGAGIPPPP 1001
Score = 34.3 bits (77), Expect = 0.36
Identities = 22/69 (31%), Positives = 27/69 (39%), Gaps = 4/69 (5%)
Query: 345 PPTLNGHLNPTSEKSAAGLPLPP--AAAAIPTPPPLPSTYLPISHPPQIVNSNSNSPSTP 402
PP + P AG+P PP IP PPPLP +P PP + + P
Sbjct: 1122 PPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIP--PPPPLPGAGIPPPPPL 1179
Query: 403 EGRGTQDLP 411
G G P
Sbjct: 1180 PGVGIPPPP 1188
Score = 33.1 bits (74), Expect = 0.81
Identities = 22/69 (31%), Positives = 26/69 (37%), Gaps = 4/69 (5%)
Query: 345 PPTLNGHLNPTSEKSAAGLPLPP--AAAAIPTPPPLPSTYLPISHPPQIVNSNSNSPSTP 402
PP + P G+P PP A IP PPPLP +P PP + P
Sbjct: 1133 PPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIP--PPPPLPGVGIPPPPPL 1190
Query: 403 EGRGTQDLP 411
G G P
Sbjct: 1191 PGVGIPPPP 1199
Score = 30.8 bits (68), Expect = 4.0
Identities = 23/67 (34%), Positives = 27/67 (40%), Gaps = 11/67 (16%)
Query: 345 PPTLNGHLNPTSEKSAAGLPLPPAAAAIPTPPPLPSTYLPISHPPQIVNSNSNSPSTPEG 404
PP L G PT LP + AIP PPPL T + PP + + P G
Sbjct: 880 PPPLPGMTVPT---------LP--STAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPG 928
Query: 405 RGTQDLP 411
G LP
Sbjct: 929 AGILPLP 935
>gi|170016091 odz, odd Oz/ten-m homolog 2 [Homo sapiens]
Length = 2765
Score = 39.7 bits (91), Expect = 0.009
Identities = 43/173 (24%), Positives = 61/173 (35%), Gaps = 8/173 (4%)
Query: 333 KKARISHLTNRVPP--TLNGHLNPTSEKSAAGLPLPPAAAAIPTPPPLPSTYLPISHPPQ 390
K R S L++R TL N G P+PP ++ P LPS LP SH P
Sbjct: 137 KSRRSSGLSSRENSALTLTDSDNENKSDDENGRPIPPTSS----PSLLPSAQLPSSHNPP 192
Query: 391 IVNSNSNSPSTPEGRGTQDL-PVDSFSQNDSIYEDQQDKYTSRTSLETLPPGSVLLKCPK 449
V+ + D P + FS N + + +S L+ P
Sbjct: 193 PVSCQMPLLDSNTSHQIMDTNPDEEFSPNSYLLRACSGPQQASSSGPPNHHSQSTLRPPL 252
Query: 450 PMEENHSMSHKKSKKKSKKHKEKDQIKKHDIETIEEKEEDLKREEEIAKLNNS 502
P NH++SH S S ++ I DL E +L +S
Sbjct: 253 PPPHNHTLSHHHSSANSLNRNSLTN-RRSQIHAPAPAPNDLATTPESVQLQDS 304
>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
sapiens]
Length = 820
Score = 39.7 bits (91), Expect = 0.009
Identities = 38/159 (23%), Positives = 76/159 (47%), Gaps = 19/159 (11%)
Query: 454 NHSMSHKKSKKKSKKHKEKDQIKKHDIETIE-EKEEDLKREEEIAKLNNSSPNSSGGVK- 511
+ S S KS ++ ++HKE+++ K+ D + ++++D R ++ K ++ SP K
Sbjct: 59 SRSRSRSKSAERERRHKERERDKERDRNKKDRDRDKDGHRRDKDRKRSSLSPGRGKDFKS 118
Query: 512 ----------EDCTASMEPSAIELPDYLIKYIAIVSYEQRQNYKDDFNAEYD-EYRALHA 560
ED +P A P L + +A E+ K F ++ + E AL
Sbjct: 119 RKDRDSKKDEEDEHGDKKPKA--QPLSLEELLAKKKAEEEAEAKPKFLSKAEREAEALKR 176
Query: 561 RMETVARRFIKLDAQRKRLSPGSKEYQNVHEEVLQEYQK 599
R + V R L+ +RK+ K++Q++ ++L++ Q+
Sbjct: 177 RQQEVEERQRMLEEERKK----RKQFQDLGRKMLEDPQE 211
>gi|28559039 mediator complex subunit 1 [Homo sapiens]
Length = 1581
Score = 39.3 bits (90), Expect = 0.011
Identities = 25/82 (30%), Positives = 42/82 (51%), Gaps = 2/82 (2%)
Query: 449 KPMEENHSMSHKKSKKKSKKHKEKDQIKKHDIETIEEKEEDLKREEEIAKLNNSSPNSSG 508
+P+ E + HKK KK+ KK K+KD+ + D + ++K +K E +K SS S
Sbjct: 1487 RPLPEYSTEKHKKHKKEKKKVKDKDRDRDRDKDRDKKKSHSIK-PESWSKSPISSDQSLS 1545
Query: 509 GVKEDCTASMEPSAIELPDYLI 530
++ PS + PD++I
Sbjct: 1546 MTSNTILSADRPSRLS-PDFMI 1566
Score = 31.2 bits (69), Expect = 3.1
Identities = 42/172 (24%), Positives = 60/172 (34%), Gaps = 26/172 (15%)
Query: 282 SLESVLSRKLNPSQNAAGTSRSESPVCSSRDAVSSP-QKRLLDSEFIDPLMNKKARISHL 340
S S LS + SQ ++G+S+S++ S SSP K L S M + + S L
Sbjct: 1122 SSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSL 1181
Query: 341 TN---RVPPTLNGHLNPTSEKSAAGLPLPPAAAAIPTPPPLPSTYLPIS----------- 386
N P H P P+ P +P PP PIS
Sbjct: 1182 MNPSLSKPNISPSHSRPPGGSDKLASPMKP----VPGTPPSSKAKSPISSGSGGSHMSGT 1237
Query: 387 -------HPPQIVNSNSNSPSTPEGRGTQDLPVDSFSQNDSIYEDQQDKYTS 431
+ +S S S TP + SFS + S Q+++ S
Sbjct: 1238 SSSSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGS 1289
>gi|161169015 neuron navigator 2 isoform 3 [Homo sapiens]
Length = 2365
Score = 39.3 bits (90), Expect = 0.011
Identities = 84/384 (21%), Positives = 143/384 (37%), Gaps = 68/384 (17%)
Query: 131 YQMTRERMTQAEEESRNRSTKVIKPGGPYVGKRVQIRKAP-QAVSDTVPERKRSTPMNPA 189
+ ++R + Q + + ++ S+ P P V Q+ AP Q + T ++ TP P
Sbjct: 121 FSLSRYKQQQQQPQKQHLSS----PLPPAVS---QVAGAPSQCQAGTPQQQVPVTPQAPC 173
Query: 190 NTIRKTHSSSTISQRPYRDRVIHLLALKAYKKPELLARLQKDGVNQKDKN-SLGAILQQV 248
+ + +Q + R+ P AR+ G K + S A ++
Sbjct: 174 QPHQPAPHQQSKAQAEMQSRL-----------PGPTARVSAAGSEAKTRGGSTTANNRRS 222
Query: 249 ANLNSKDLSYTLKDYVFKELQRDWPGYSEIDRRSLESVLSRKLNPSQNAAGTSRSESPV- 307
+ N+ D S K + P S ++ L S S S NA + S S
Sbjct: 223 QSFNNYDKS--------KPVTSPPPPPSSHEKEPLASSASSHPGMSDNAPASLESGSSST 274
Query: 308 ---CSSRDAVSSPQKRLLDSEFIDPLMNKKARISHLTNRVPPTLNGHLNPTSEKSAAGLP 364
CS+ A+ P P +K + H ++ S +
Sbjct: 275 PTNCSTSSAIPQP------GAATKPWRSKSLSVKH---------------SATVSMLSVK 313
Query: 365 LPPAAAAIPTPP---PLPSTYLPISHPPQIVNSNSNSPSTPEGRGTQDLPVDSFSQNDSI 421
P A PTP P P+ + ++ NS S + EG G++D + S
Sbjct: 314 PPGPEAPRPTPEAMKPAPNNQKSMLEKLKLFNSKGGSKAG-EGPGSRDTSCERLETLPSF 372
Query: 422 YEDQQDKYTSRTSLETLPPGS----VLLKCPKPMEENHSMSHKKS------KKKSKKHKE 471
E ++ + SR L T+ P S + LK + ++++KKS K+K K+ +E
Sbjct: 373 EESEELEAASRM-LTTVGPASSSPKIALKGIAQRTFSRALTNKKSSLKGNEKEKEKQQRE 431
Query: 472 KDQIKKHDIETIEEKEEDLKREEE 495
KD+ K D+ E L +EE
Sbjct: 432 KDKEKSKDLAKRASVTERLDLKEE 455
>gi|161169013 neuron navigator 2 isoform 1 [Homo sapiens]
Length = 2432
Score = 39.3 bits (90), Expect = 0.011
Identities = 84/384 (21%), Positives = 143/384 (37%), Gaps = 68/384 (17%)
Query: 131 YQMTRERMTQAEEESRNRSTKVIKPGGPYVGKRVQIRKAP-QAVSDTVPERKRSTPMNPA 189
+ ++R + Q + + ++ S+ P P V Q+ AP Q + T ++ TP P
Sbjct: 185 FSLSRYKQQQQQPQKQHLSS----PLPPAVS---QVAGAPSQCQAGTPQQQVPVTPQAPC 237
Query: 190 NTIRKTHSSSTISQRPYRDRVIHLLALKAYKKPELLARLQKDGVNQKDKN-SLGAILQQV 248
+ + +Q + R+ P AR+ G K + S A ++
Sbjct: 238 QPHQPAPHQQSKAQAEMQSRL-----------PGPTARVSAAGSEAKTRGGSTTANNRRS 286
Query: 249 ANLNSKDLSYTLKDYVFKELQRDWPGYSEIDRRSLESVLSRKLNPSQNAAGTSRSESPV- 307
+ N+ D S K + P S ++ L S S S NA + S S
Sbjct: 287 QSFNNYDKS--------KPVTSPPPPPSSHEKEPLASSASSHPGMSDNAPASLESGSSST 338
Query: 308 ---CSSRDAVSSPQKRLLDSEFIDPLMNKKARISHLTNRVPPTLNGHLNPTSEKSAAGLP 364
CS+ A+ P P +K + H ++ S +
Sbjct: 339 PTNCSTSSAIPQP------GAATKPWRSKSLSVKH---------------SATVSMLSVK 377
Query: 365 LPPAAAAIPTPP---PLPSTYLPISHPPQIVNSNSNSPSTPEGRGTQDLPVDSFSQNDSI 421
P A PTP P P+ + ++ NS S + EG G++D + S
Sbjct: 378 PPGPEAPRPTPEAMKPAPNNQKSMLEKLKLFNSKGGSKAG-EGPGSRDTSCERLETLPSF 436
Query: 422 YEDQQDKYTSRTSLETLPPGS----VLLKCPKPMEENHSMSHKKS------KKKSKKHKE 471
E ++ + SR L T+ P S + LK + ++++KKS K+K K+ +E
Sbjct: 437 EESEELEAASRM-LTTVGPASSSPKIALKGIAQRTFSRALTNKKSSLKGNEKEKEKQQRE 495
Query: 472 KDQIKKHDIETIEEKEEDLKREEE 495
KD+ K D+ E L +EE
Sbjct: 496 KDKEKSKDLAKRASVTERLDLKEE 519
>gi|38044282 neuron navigator 2 isoform 2 [Homo sapiens]
Length = 2429
Score = 39.3 bits (90), Expect = 0.011
Identities = 84/384 (21%), Positives = 143/384 (37%), Gaps = 68/384 (17%)
Query: 131 YQMTRERMTQAEEESRNRSTKVIKPGGPYVGKRVQIRKAP-QAVSDTVPERKRSTPMNPA 189
+ ++R + Q + + ++ S+ P P V Q+ AP Q + T ++ TP P
Sbjct: 185 FSLSRYKQQQQQPQKQHLSS----PLPPAVS---QVAGAPSQCQAGTPQQQVPVTPQAPC 237
Query: 190 NTIRKTHSSSTISQRPYRDRVIHLLALKAYKKPELLARLQKDGVNQKDKN-SLGAILQQV 248
+ + +Q + R+ P AR+ G K + S A ++
Sbjct: 238 QPHQPAPHQQSKAQAEMQSRL-----------PGPTARVSAAGSEAKTRGGSTTANNRRS 286
Query: 249 ANLNSKDLSYTLKDYVFKELQRDWPGYSEIDRRSLESVLSRKLNPSQNAAGTSRSESPV- 307
+ N+ D S K + P S ++ L S S S NA + S S
Sbjct: 287 QSFNNYDKS--------KPVTSPPPPPSSHEKEPLASSASSHPGMSDNAPASLESGSSST 338
Query: 308 ---CSSRDAVSSPQKRLLDSEFIDPLMNKKARISHLTNRVPPTLNGHLNPTSEKSAAGLP 364
CS+ A+ P P +K + H ++ S +
Sbjct: 339 PTNCSTSSAIPQP------GAATKPWRSKSLSVKH---------------SATVSMLSVK 377
Query: 365 LPPAAAAIPTPP---PLPSTYLPISHPPQIVNSNSNSPSTPEGRGTQDLPVDSFSQNDSI 421
P A PTP P P+ + ++ NS S + EG G++D + S
Sbjct: 378 PPGPEAPRPTPEAMKPAPNNQKSMLEKLKLFNSKGGSKAG-EGPGSRDTSCERLETLPSF 436
Query: 422 YEDQQDKYTSRTSLETLPPGS----VLLKCPKPMEENHSMSHKKS------KKKSKKHKE 471
E ++ + SR L T+ P S + LK + ++++KKS K+K K+ +E
Sbjct: 437 EESEELEAASRM-LTTVGPASSSPKIALKGIAQRTFSRALTNKKSSLKGNEKEKEKQQRE 495
Query: 472 KDQIKKHDIETIEEKEEDLKREEE 495
KD+ K D+ E L +EE
Sbjct: 496 KDKEKSKDLAKRASVTERLDLKEE 519
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.128 0.364
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,044,107
Number of Sequences: 37866
Number of extensions: 1398447
Number of successful extensions: 13821
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 148
Number of HSP's successfully gapped in prelim test: 596
Number of HSP's that attempted gapping in prelim test: 10277
Number of HSP's gapped (non-prelim): 3240
length of query: 640
length of database: 18,247,518
effective HSP length: 109
effective length of query: 531
effective length of database: 14,120,124
effective search space: 7497785844
effective search space used: 7497785844
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.