Search of human proteins with 155030226

Search of human proteins with 155030226

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|155030226 phosphatidylinositol 4-kinase type 3 alpha isoform
2 [Homo sapiens]
         (2044 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|155030226 phosphatidylinositol 4-kinase type 3 alpha isoform ...  4110   0.0  
gi|4505807 phosphatidylinositol 4-kinase type 3 alpha isoform 1 ...  1738   0.0  
gi|239757646 PREDICTED: similar to phosphatidylinositol 4-kinase...   393   e-108
gi|4505809 catalytic phosphatidylinositol 4-kinase beta [Homo sa...   193   1e-48
gi|54792082 phosphoinositide-3-kinase, catalytic, alpha polypept...   154   1e-36
gi|21237725 phosphoinositide-3-kinase, catalytic, gamma polypept...   137   1e-31
gi|194353959 phosphoinositide-3-kinase, class 2 gamma polypeptid...   136   2e-31
gi|194097347 phosphoinositide-3-kinase, class 2 beta polypeptide...   130   1e-29
gi|157671929 phosphoinositide-3-kinase, class 2 alpha polypeptid...   127   9e-29
gi|34761064 catalytic phosphatidylinositol 3-kinase 3 [Homo sapi...   116   2e-25
gi|5453894 catalytic phosphatidylinositol 3-kinase beta [Homo sa...   115   6e-25
gi|156564405 catalytic phosphatidylinositol 3-kinase delta [Homo...   112   5e-24
gi|4826730 FK506 binding protein 12-rapamycin associated protein...    48   9e-05
gi|157266317 ataxia telangiectasia and Rad3 related protein [Hom...    44   0.002
gi|169165926 PREDICTED: similar to ataxia telangiectasia and Rad...    44   0.002
gi|20336199 ataxia telangiectasia mutated isoform 2 [Homo sapiens]     38   0.089
gi|71902540 ataxia telangiectasia mutated isoform 1 [Homo sapiens]     38   0.089
gi|169218268 PREDICTED: similar to Serine-protein kinase ATM, pa...    38   0.089
gi|62243658 PI-3-kinase-related kinase SMG-1 [Homo sapiens]            38   0.089
gi|226246554 hypothetical protein LOC643677 [Homo sapiens]             36   0.44 
gi|239756039 PREDICTED: hypothetical protein LOC643677 [Homo sap...    36   0.44 
gi|239750569 PREDICTED: hypothetical protein LOC643677 [Homo sap...    36   0.44 
gi|239744870 PREDICTED: hypothetical protein LOC643677 [Homo sap...    36   0.44 
gi|19924149 toll-like receptor 4 precursor [Homo sapiens]              34   1.3  
gi|126032350 protein kinase, DNA-activated, catalytic polypeptid...    34   1.3  
gi|113430845 PREDICTED: similar to protein kinase, DNA-activated...    34   1.3  
gi|171184451 centrosome-associated protein 350 [Homo sapiens]          34   1.3  
gi|194394141 nucleolar preribosomal-associated protein 1 [Homo s...    34   1.7  
gi|59710093 G-protein coupled receptor 112 [Homo sapiens]              33   2.9  
gi|13654237 protein kinase, DNA-activated, catalytic polypeptide...    33   3.7  

>gi|155030226 phosphatidylinositol 4-kinase type 3 alpha isoform 2
            [Homo sapiens]
          Length = 2044

 Score = 4110 bits (10658), Expect = 0.0
 Identities = 2044/2044 (100%), Positives = 2044/2044 (100%)

Query: 1    MCPVDFHGIFQLDERRRDAVIALGIFLIESDLQHKDCVVPYLLRLLKGLPKVYWVEESTA 60
            MCPVDFHGIFQLDERRRDAVIALGIFLIESDLQHKDCVVPYLLRLLKGLPKVYWVEESTA
Sbjct: 1    MCPVDFHGIFQLDERRRDAVIALGIFLIESDLQHKDCVVPYLLRLLKGLPKVYWVEESTA 60

Query: 61   RKGRGALPVAESFSFCLVTLLSDVAYRDPSLRDEILEVLLQVLHVLLGMCQALEIQDKEY 120
            RKGRGALPVAESFSFCLVTLLSDVAYRDPSLRDEILEVLLQVLHVLLGMCQALEIQDKEY
Sbjct: 61   RKGRGALPVAESFSFCLVTLLSDVAYRDPSLRDEILEVLLQVLHVLLGMCQALEIQDKEY 120

Query: 121  LCKYAIPCLIGISRAFGRYSNMEESLLSKLFPKIPPHSLRVLEELEGVRRRSFNDFRSIL 180
            LCKYAIPCLIGISRAFGRYSNMEESLLSKLFPKIPPHSLRVLEELEGVRRRSFNDFRSIL
Sbjct: 121  LCKYAIPCLIGISRAFGRYSNMEESLLSKLFPKIPPHSLRVLEELEGVRRRSFNDFRSIL 180

Query: 181  PSNLLTVCQEGTLKRKTSSVSSISQVSPERGMPPPSSPGGSAFHYFEASCLPDGTALEPE 240
            PSNLLTVCQEGTLKRKTSSVSSISQVSPERGMPPPSSPGGSAFHYFEASCLPDGTALEPE
Sbjct: 181  PSNLLTVCQEGTLKRKTSSVSSISQVSPERGMPPPSSPGGSAFHYFEASCLPDGTALEPE 240

Query: 241  YYFSTISSSFSVSPLFNGVTYKEFNIPLEMLRELLNLVKKIVEEAVLKSLDAIVASVMEA 300
            YYFSTISSSFSVSPLFNGVTYKEFNIPLEMLRELLNLVKKIVEEAVLKSLDAIVASVMEA
Sbjct: 241  YYFSTISSSFSVSPLFNGVTYKEFNIPLEMLRELLNLVKKIVEEAVLKSLDAIVASVMEA 300

Query: 301  NPSADLYYTSFSDPLYLTMFKMLRDTLYYMKDLPTSFVKEIHDFVLEQFNTSQGELQKIL 360
            NPSADLYYTSFSDPLYLTMFKMLRDTLYYMKDLPTSFVKEIHDFVLEQFNTSQGELQKIL
Sbjct: 301  NPSADLYYTSFSDPLYLTMFKMLRDTLYYMKDLPTSFVKEIHDFVLEQFNTSQGELQKIL 360

Query: 361  HDADRIHNELSPLKLRCQANAACVDLMVWAVKDEQGAENLCIKLSEKLQSKTSSKVIIAH 420
            HDADRIHNELSPLKLRCQANAACVDLMVWAVKDEQGAENLCIKLSEKLQSKTSSKVIIAH
Sbjct: 361  HDADRIHNELSPLKLRCQANAACVDLMVWAVKDEQGAENLCIKLSEKLQSKTSSKVIIAH 420

Query: 421  LPLLICCLQGLGRLCERFPVVVHSVTPSLRDFLVIPSPVLVKLYKYHSQYHTVAGNDIKI 480
            LPLLICCLQGLGRLCERFPVVVHSVTPSLRDFLVIPSPVLVKLYKYHSQYHTVAGNDIKI
Sbjct: 421  LPLLICCLQGLGRLCERFPVVVHSVTPSLRDFLVIPSPVLVKLYKYHSQYHTVAGNDIKI 480

Query: 481  SVTNEHSESTLNVMSGKKSQPSMYEQLRDIAIDNICRCLKAGLTVDPVIVEAFLASLSNR 540
            SVTNEHSESTLNVMSGKKSQPSMYEQLRDIAIDNICRCLKAGLTVDPVIVEAFLASLSNR
Sbjct: 481  SVTNEHSESTLNVMSGKKSQPSMYEQLRDIAIDNICRCLKAGLTVDPVIVEAFLASLSNR 540

Query: 541  LYISQESDKDAHLIPDHTIRALGHIAVALRDTPKVMEPILQILQQKFCQPPSPLDVLIID 600
            LYISQESDKDAHLIPDHTIRALGHIAVALRDTPKVMEPILQILQQKFCQPPSPLDVLIID
Sbjct: 541  LYISQESDKDAHLIPDHTIRALGHIAVALRDTPKVMEPILQILQQKFCQPPSPLDVLIID 600

Query: 601  QLGCLVITGNQYIYQEVWNLFQQISVKASSVVYSATKDYKDHGYRHCSLAVINALANIAA 660
            QLGCLVITGNQYIYQEVWNLFQQISVKASSVVYSATKDYKDHGYRHCSLAVINALANIAA
Sbjct: 601  QLGCLVITGNQYIYQEVWNLFQQISVKASSVVYSATKDYKDHGYRHCSLAVINALANIAA 660

Query: 661  NIQDEHLVDELLMNLLELFVQLGLEGKRASERASEKGPALKASSSAGNLGVLIPVIAVLT 720
            NIQDEHLVDELLMNLLELFVQLGLEGKRASERASEKGPALKASSSAGNLGVLIPVIAVLT
Sbjct: 661  NIQDEHLVDELLMNLLELFVQLGLEGKRASERASEKGPALKASSSAGNLGVLIPVIAVLT 720

Query: 721  RRLPPIKEAKPRLQKLFRDFWLYSVLMGFAVEGSGLWPEEWYEGVCEIATKSPLLTFPSK 780
            RRLPPIKEAKPRLQKLFRDFWLYSVLMGFAVEGSGLWPEEWYEGVCEIATKSPLLTFPSK
Sbjct: 721  RRLPPIKEAKPRLQKLFRDFWLYSVLMGFAVEGSGLWPEEWYEGVCEIATKSPLLTFPSK 780

Query: 781  EPLRSVLQYNSAMKNDTVTPAELSELRSTIINLLDPPPEVSALINKLDFAMSTYLLSVYR 840
            EPLRSVLQYNSAMKNDTVTPAELSELRSTIINLLDPPPEVSALINKLDFAMSTYLLSVYR
Sbjct: 781  EPLRSVLQYNSAMKNDTVTPAELSELRSTIINLLDPPPEVSALINKLDFAMSTYLLSVYR 840

Query: 841  LEYMRVLRSTDPDRFQVMFCYFEDKAIQKDKSGMMQCVIAVADKVFDAFLNMMADKAKTK 900
            LEYMRVLRSTDPDRFQVMFCYFEDKAIQKDKSGMMQCVIAVADKVFDAFLNMMADKAKTK
Sbjct: 841  LEYMRVLRSTDPDRFQVMFCYFEDKAIQKDKSGMMQCVIAVADKVFDAFLNMMADKAKTK 900

Query: 901  ENEEELERHAQFLLVNFNHIHKRIRRVADKYLSGLVDKFPHLLWSGTVLKTMLDILQTLS 960
            ENEEELERHAQFLLVNFNHIHKRIRRVADKYLSGLVDKFPHLLWSGTVLKTMLDILQTLS
Sbjct: 901  ENEEELERHAQFLLVNFNHIHKRIRRVADKYLSGLVDKFPHLLWSGTVLKTMLDILQTLS 960

Query: 961  LSLSADIHKDQPYYDIPDAPYRITVPDTYEARESIVKDFAARCGMILQEAMKWAPTVTKS 1020
            LSLSADIHKDQPYYDIPDAPYRITVPDTYEARESIVKDFAARCGMILQEAMKWAPTVTKS
Sbjct: 961  LSLSADIHKDQPYYDIPDAPYRITVPDTYEARESIVKDFAARCGMILQEAMKWAPTVTKS 1020

Query: 1021 HLQEYLNKHQNWVSGLSQHTGLAMATESILHFAGYNKQNTTLGATQLSERPACVKKDYSN 1080
            HLQEYLNKHQNWVSGLSQHTGLAMATESILHFAGYNKQNTTLGATQLSERPACVKKDYSN
Sbjct: 1021 HLQEYLNKHQNWVSGLSQHTGLAMATESILHFAGYNKQNTTLGATQLSERPACVKKDYSN 1080

Query: 1081 FMASLNLRNRYAGEVYGMIRFSGTTGQMSDLNKMMVQDLHSALDRSHPQHYTQAMFKLTA 1140
            FMASLNLRNRYAGEVYGMIRFSGTTGQMSDLNKMMVQDLHSALDRSHPQHYTQAMFKLTA
Sbjct: 1081 FMASLNLRNRYAGEVYGMIRFSGTTGQMSDLNKMMVQDLHSALDRSHPQHYTQAMFKLTA 1140

Query: 1141 MLISSKDCDPQLLHHLCWGPLRMFNEHGMETALACWEWLLAGKDGVEVPFMREMAGAWHM 1200
            MLISSKDCDPQLLHHLCWGPLRMFNEHGMETALACWEWLLAGKDGVEVPFMREMAGAWHM
Sbjct: 1141 MLISSKDCDPQLLHHLCWGPLRMFNEHGMETALACWEWLLAGKDGVEVPFMREMAGAWHM 1200

Query: 1201 TVEQKFGLFSAEIKEADPLAASEASQPKPCPPEVTPHYIWIDFLVQRFEIAKYCSSDQVE 1260
            TVEQKFGLFSAEIKEADPLAASEASQPKPCPPEVTPHYIWIDFLVQRFEIAKYCSSDQVE
Sbjct: 1201 TVEQKFGLFSAEIKEADPLAASEASQPKPCPPEVTPHYIWIDFLVQRFEIAKYCSSDQVE 1260

Query: 1261 IFSSLLQRSMSLNIGGAKGSMNRHVAAIGPRFKLLTLGLSLLHADVVPNATIRNVLREKI 1320
            IFSSLLQRSMSLNIGGAKGSMNRHVAAIGPRFKLLTLGLSLLHADVVPNATIRNVLREKI
Sbjct: 1261 IFSSLLQRSMSLNIGGAKGSMNRHVAAIGPRFKLLTLGLSLLHADVVPNATIRNVLREKI 1320

Query: 1321 YSTAFDYFSCPPKFPTQGEKRLREDISIMIKFWTAMFSDKKYLTASQLVPPDNQDTRSNL 1380
            YSTAFDYFSCPPKFPTQGEKRLREDISIMIKFWTAMFSDKKYLTASQLVPPDNQDTRSNL
Sbjct: 1321 YSTAFDYFSCPPKFPTQGEKRLREDISIMIKFWTAMFSDKKYLTASQLVPPDNQDTRSNL 1380

Query: 1381 DITVGSRQQATQGWINTYPLSSGMSTISKKSGMSKKTNRGSQLHKYYMKRRTLLLSLLAT 1440
            DITVGSRQQATQGWINTYPLSSGMSTISKKSGMSKKTNRGSQLHKYYMKRRTLLLSLLAT
Sbjct: 1381 DITVGSRQQATQGWINTYPLSSGMSTISKKSGMSKKTNRGSQLHKYYMKRRTLLLSLLAT 1440

Query: 1441 EIERLITWYNPLSAPELELDQAGENSVANWRSKYISLSEKQWKDNVNLAWSISPYLAVQL 1500
            EIERLITWYNPLSAPELELDQAGENSVANWRSKYISLSEKQWKDNVNLAWSISPYLAVQL
Sbjct: 1441 EIERLITWYNPLSAPELELDQAGENSVANWRSKYISLSEKQWKDNVNLAWSISPYLAVQL 1500

Query: 1501 PARFKNTEAIGNEVTRLVRLDPGAVSDVPEAIKFLVTWHTIDADAPELSHVLCWAPTDPP 1560
            PARFKNTEAIGNEVTRLVRLDPGAVSDVPEAIKFLVTWHTIDADAPELSHVLCWAPTDPP
Sbjct: 1501 PARFKNTEAIGNEVTRLVRLDPGAVSDVPEAIKFLVTWHTIDADAPELSHVLCWAPTDPP 1560

Query: 1561 TGLSYFSSMYPPHPLTAQYGVKVLRSFPPDAILFYIPQIVQALRYDKMGYVREYILWAAS 1620
            TGLSYFSSMYPPHPLTAQYGVKVLRSFPPDAILFYIPQIVQALRYDKMGYVREYILWAAS
Sbjct: 1561 TGLSYFSSMYPPHPLTAQYGVKVLRSFPPDAILFYIPQIVQALRYDKMGYVREYILWAAS 1620

Query: 1621 KSQLLAHQFIWNMKTNIYLDEEGHQKDPDIGDLLDQLVEEITGSLSGPAKDFYQREFDFF 1680
            KSQLLAHQFIWNMKTNIYLDEEGHQKDPDIGDLLDQLVEEITGSLSGPAKDFYQREFDFF
Sbjct: 1621 KSQLLAHQFIWNMKTNIYLDEEGHQKDPDIGDLLDQLVEEITGSLSGPAKDFYQREFDFF 1680

Query: 1681 NKITNVSAIIKPYPKGDERKKACLSALSEVKVQPGCYLPSNPEAIVLDIDYKSGTPMQSA 1740
            NKITNVSAIIKPYPKGDERKKACLSALSEVKVQPGCYLPSNPEAIVLDIDYKSGTPMQSA
Sbjct: 1681 NKITNVSAIIKPYPKGDERKKACLSALSEVKVQPGCYLPSNPEAIVLDIDYKSGTPMQSA 1740

Query: 1741 AKAPYLAKFKVKRCGVSELEKEGLRCRSDSEDECSTQEADGQKISWQAAIFKVGDDCRQD 1800
            AKAPYLAKFKVKRCGVSELEKEGLRCRSDSEDECSTQEADGQKISWQAAIFKVGDDCRQD
Sbjct: 1741 AKAPYLAKFKVKRCGVSELEKEGLRCRSDSEDECSTQEADGQKISWQAAIFKVGDDCRQD 1800

Query: 1801 MLALQIIDLFKNIFQLVGLDLFVFPYRVVATAPGCGVIECIPDCTSRDQLGRQTDFGMYD 1860
            MLALQIIDLFKNIFQLVGLDLFVFPYRVVATAPGCGVIECIPDCTSRDQLGRQTDFGMYD
Sbjct: 1801 MLALQIIDLFKNIFQLVGLDLFVFPYRVVATAPGCGVIECIPDCTSRDQLGRQTDFGMYD 1860

Query: 1861 YFTRQYGDESTLAFQQARYNFIRSMAAYSLLLFLLQIKDRHNGNIMLDKKGHIIHIDFGF 1920
            YFTRQYGDESTLAFQQARYNFIRSMAAYSLLLFLLQIKDRHNGNIMLDKKGHIIHIDFGF
Sbjct: 1861 YFTRQYGDESTLAFQQARYNFIRSMAAYSLLLFLLQIKDRHNGNIMLDKKGHIIHIDFGF 1920

Query: 1921 MFESSPGGNLGWEPDIKLTDEMVMIMGGKMEATPFKWFMEMCVRGYLAVRPYMDAVVSLV 1980
            MFESSPGGNLGWEPDIKLTDEMVMIMGGKMEATPFKWFMEMCVRGYLAVRPYMDAVVSLV
Sbjct: 1921 MFESSPGGNLGWEPDIKLTDEMVMIMGGKMEATPFKWFMEMCVRGYLAVRPYMDAVVSLV 1980

Query: 1981 TLMLDTGLPCFRGQTIKLLKHRFSPNMTEREAANFIMKVIQSCFLSNRSRTYDMIQYYQN 2040
            TLMLDTGLPCFRGQTIKLLKHRFSPNMTEREAANFIMKVIQSCFLSNRSRTYDMIQYYQN
Sbjct: 1981 TLMLDTGLPCFRGQTIKLLKHRFSPNMTEREAANFIMKVIQSCFLSNRSRTYDMIQYYQN 2040

Query: 2041 DIPY 2044
            DIPY
Sbjct: 2041 DIPY 2044


>gi|4505807 phosphatidylinositol 4-kinase type 3 alpha isoform 1 [Homo
            sapiens]
          Length = 854

 Score = 1738 bits (4500), Expect = 0.0
 Identities = 854/854 (100%), Positives = 854/854 (100%)

Query: 1191 MREMAGAWHMTVEQKFGLFSAEIKEADPLAASEASQPKPCPPEVTPHYIWIDFLVQRFEI 1250
            MREMAGAWHMTVEQKFGLFSAEIKEADPLAASEASQPKPCPPEVTPHYIWIDFLVQRFEI
Sbjct: 1    MREMAGAWHMTVEQKFGLFSAEIKEADPLAASEASQPKPCPPEVTPHYIWIDFLVQRFEI 60

Query: 1251 AKYCSSDQVEIFSSLLQRSMSLNIGGAKGSMNRHVAAIGPRFKLLTLGLSLLHADVVPNA 1310
            AKYCSSDQVEIFSSLLQRSMSLNIGGAKGSMNRHVAAIGPRFKLLTLGLSLLHADVVPNA
Sbjct: 61   AKYCSSDQVEIFSSLLQRSMSLNIGGAKGSMNRHVAAIGPRFKLLTLGLSLLHADVVPNA 120

Query: 1311 TIRNVLREKIYSTAFDYFSCPPKFPTQGEKRLREDISIMIKFWTAMFSDKKYLTASQLVP 1370
            TIRNVLREKIYSTAFDYFSCPPKFPTQGEKRLREDISIMIKFWTAMFSDKKYLTASQLVP
Sbjct: 121  TIRNVLREKIYSTAFDYFSCPPKFPTQGEKRLREDISIMIKFWTAMFSDKKYLTASQLVP 180

Query: 1371 PDNQDTRSNLDITVGSRQQATQGWINTYPLSSGMSTISKKSGMSKKTNRGSQLHKYYMKR 1430
            PDNQDTRSNLDITVGSRQQATQGWINTYPLSSGMSTISKKSGMSKKTNRGSQLHKYYMKR
Sbjct: 181  PDNQDTRSNLDITVGSRQQATQGWINTYPLSSGMSTISKKSGMSKKTNRGSQLHKYYMKR 240

Query: 1431 RTLLLSLLATEIERLITWYNPLSAPELELDQAGENSVANWRSKYISLSEKQWKDNVNLAW 1490
            RTLLLSLLATEIERLITWYNPLSAPELELDQAGENSVANWRSKYISLSEKQWKDNVNLAW
Sbjct: 241  RTLLLSLLATEIERLITWYNPLSAPELELDQAGENSVANWRSKYISLSEKQWKDNVNLAW 300

Query: 1491 SISPYLAVQLPARFKNTEAIGNEVTRLVRLDPGAVSDVPEAIKFLVTWHTIDADAPELSH 1550
            SISPYLAVQLPARFKNTEAIGNEVTRLVRLDPGAVSDVPEAIKFLVTWHTIDADAPELSH
Sbjct: 301  SISPYLAVQLPARFKNTEAIGNEVTRLVRLDPGAVSDVPEAIKFLVTWHTIDADAPELSH 360

Query: 1551 VLCWAPTDPPTGLSYFSSMYPPHPLTAQYGVKVLRSFPPDAILFYIPQIVQALRYDKMGY 1610
            VLCWAPTDPPTGLSYFSSMYPPHPLTAQYGVKVLRSFPPDAILFYIPQIVQALRYDKMGY
Sbjct: 361  VLCWAPTDPPTGLSYFSSMYPPHPLTAQYGVKVLRSFPPDAILFYIPQIVQALRYDKMGY 420

Query: 1611 VREYILWAASKSQLLAHQFIWNMKTNIYLDEEGHQKDPDIGDLLDQLVEEITGSLSGPAK 1670
            VREYILWAASKSQLLAHQFIWNMKTNIYLDEEGHQKDPDIGDLLDQLVEEITGSLSGPAK
Sbjct: 421  VREYILWAASKSQLLAHQFIWNMKTNIYLDEEGHQKDPDIGDLLDQLVEEITGSLSGPAK 480

Query: 1671 DFYQREFDFFNKITNVSAIIKPYPKGDERKKACLSALSEVKVQPGCYLPSNPEAIVLDID 1730
            DFYQREFDFFNKITNVSAIIKPYPKGDERKKACLSALSEVKVQPGCYLPSNPEAIVLDID
Sbjct: 481  DFYQREFDFFNKITNVSAIIKPYPKGDERKKACLSALSEVKVQPGCYLPSNPEAIVLDID 540

Query: 1731 YKSGTPMQSAAKAPYLAKFKVKRCGVSELEKEGLRCRSDSEDECSTQEADGQKISWQAAI 1790
            YKSGTPMQSAAKAPYLAKFKVKRCGVSELEKEGLRCRSDSEDECSTQEADGQKISWQAAI
Sbjct: 541  YKSGTPMQSAAKAPYLAKFKVKRCGVSELEKEGLRCRSDSEDECSTQEADGQKISWQAAI 600

Query: 1791 FKVGDDCRQDMLALQIIDLFKNIFQLVGLDLFVFPYRVVATAPGCGVIECIPDCTSRDQL 1850
            FKVGDDCRQDMLALQIIDLFKNIFQLVGLDLFVFPYRVVATAPGCGVIECIPDCTSRDQL
Sbjct: 601  FKVGDDCRQDMLALQIIDLFKNIFQLVGLDLFVFPYRVVATAPGCGVIECIPDCTSRDQL 660

Query: 1851 GRQTDFGMYDYFTRQYGDESTLAFQQARYNFIRSMAAYSLLLFLLQIKDRHNGNIMLDKK 1910
            GRQTDFGMYDYFTRQYGDESTLAFQQARYNFIRSMAAYSLLLFLLQIKDRHNGNIMLDKK
Sbjct: 661  GRQTDFGMYDYFTRQYGDESTLAFQQARYNFIRSMAAYSLLLFLLQIKDRHNGNIMLDKK 720

Query: 1911 GHIIHIDFGFMFESSPGGNLGWEPDIKLTDEMVMIMGGKMEATPFKWFMEMCVRGYLAVR 1970
            GHIIHIDFGFMFESSPGGNLGWEPDIKLTDEMVMIMGGKMEATPFKWFMEMCVRGYLAVR
Sbjct: 721  GHIIHIDFGFMFESSPGGNLGWEPDIKLTDEMVMIMGGKMEATPFKWFMEMCVRGYLAVR 780

Query: 1971 PYMDAVVSLVTLMLDTGLPCFRGQTIKLLKHRFSPNMTEREAANFIMKVIQSCFLSNRSR 2030
            PYMDAVVSLVTLMLDTGLPCFRGQTIKLLKHRFSPNMTEREAANFIMKVIQSCFLSNRSR
Sbjct: 781  PYMDAVVSLVTLMLDTGLPCFRGQTIKLLKHRFSPNMTEREAANFIMKVIQSCFLSNRSR 840

Query: 2031 TYDMIQYYQNDIPY 2044
            TYDMIQYYQNDIPY
Sbjct: 841  TYDMIQYYQNDIPY 854


>gi|239757646 PREDICTED: similar to phosphatidylinositol 4-kinase type
            3 alpha [Homo sapiens]
          Length = 286

 Score =  393 bits (1009), Expect = e-108
 Identities = 191/192 (99%), Positives = 192/192 (100%)

Query: 1737 MQSAAKAPYLAKFKVKRCGVSELEKEGLRCRSDSEDECSTQEADGQKISWQAAIFKVGDD 1796
            MQSAAKAPYLAKFKVKRCGVSELEKEGLRCRSDSEDECSTQEADGQKISWQAAIFK+GDD
Sbjct: 1    MQSAAKAPYLAKFKVKRCGVSELEKEGLRCRSDSEDECSTQEADGQKISWQAAIFKLGDD 60

Query: 1797 CRQDMLALQIIDLFKNIFQLVGLDLFVFPYRVVATAPGCGVIECIPDCTSRDQLGRQTDF 1856
            CRQDMLALQIIDLFKNIFQLVGLDLFVFPYRVVATAPGCGVIECIPDCTSRDQLGRQTDF
Sbjct: 61   CRQDMLALQIIDLFKNIFQLVGLDLFVFPYRVVATAPGCGVIECIPDCTSRDQLGRQTDF 120

Query: 1857 GMYDYFTRQYGDESTLAFQQARYNFIRSMAAYSLLLFLLQIKDRHNGNIMLDKKGHIIHI 1916
            GMYDYFTRQYGDESTLAFQQARYNFIRSMAAYSLLLFLLQIKDRHNGNIMLDKKGHIIHI
Sbjct: 121  GMYDYFTRQYGDESTLAFQQARYNFIRSMAAYSLLLFLLQIKDRHNGNIMLDKKGHIIHI 180

Query: 1917 DFGFMFESSPGG 1928
            DFGFMFESSPGG
Sbjct: 181  DFGFMFESSPGG 192


>gi|4505809 catalytic phosphatidylinositol 4-kinase beta [Homo
            sapiens]
          Length = 828

 Score =  193 bits (491), Expect = 1e-48
 Identities = 105/267 (39%), Positives = 166/267 (62%), Gaps = 7/267 (2%)

Query: 1781 GQKISWQ--AAIFKVGDDCRQDMLALQIIDLFKNIFQLVGLDLFVFPYRVVATAPGCGVI 1838
            G   +W+  + I K GDD RQ++LA Q++   ++I++   + L++ PY+++  +   G+I
Sbjct: 563  GHLPNWRLLSVIVKCGDDLRQELLAFQVLKQLQSIWEQERVPLWIKPYKILVISADSGMI 622

Query: 1839 ECIPDCTSRDQLGRQTDFGMYDYFTRQYGDESTLAFQQARYNFIRSMAAYSLLLFLLQIK 1898
            E + +  S  Q+ +Q+   + DYF +++G  +T AF  A+ NF++S A Y L+ +LLQ+K
Sbjct: 623  EPVVNAVSIHQVKKQSQLSLLDYFLQEHGSYTTEAFLSAQRNFVQSCAGYCLVCYLLQVK 682

Query: 1899 DRHNGNIMLDKKGHIIHIDFGFMFESSPGGNLGWEPD-IKLTDEMVMIMGGKMEATPFKW 1957
            DRHNGNI+LD +GHIIHIDFGF+  SSP  NLG+E    KLT E V +MGG ++   F +
Sbjct: 683  DRHNGNILLDAEGHIIHIDFGFILSSSP-RNLGFETSAFKLTTEFVDVMGG-LDGDMFNY 740

Query: 1958 FMEMCVRGYLAVRPYMDAVVSLVTLMLD-TGLPCFRG-QTIKLLKHRFSPNMTEREAANF 2015
            +  + ++G +A R +MD VV +V +M   + LPCF G  TI+ LK RF  +MTE +    
Sbjct: 741  YKMLMLQGLIAARKHMDKVVQIVEIMQQGSQLPCFHGSSTIRNLKERFHMSMTEEQLQLL 800

Query: 2016 IMKVIQSCFLSNRSRTYDMIQYYQNDI 2042
            + +++     S  ++ YD  QY  N I
Sbjct: 801  VEQMVDGSMRSITTKLYDGFQYLTNGI 827


>gi|54792082 phosphoinositide-3-kinase, catalytic, alpha polypeptide
            [Homo sapiens]
          Length = 1068

 Score =  154 bits (388), Expect = 1e-36
 Identities = 140/517 (27%), Positives = 225/517 (43%), Gaps = 62/517 (11%)

Query: 1528 VPEAIKFL---VTWHTIDADAPELSHVLCWAPTDPPTGLSYFSSMYPPHPLTAQYGVKVL 1584
            +PE +  L   V W++ D  A     V  W P  P   +      YP  P+   + V+ L
Sbjct: 561  IPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPD-PMVRGFAVRCL 619

Query: 1585 RSF-PPDAILFYIPQIVQALRYDKM--GYVREYILWAASKSQLLAHQFIWNMKTNIYLDE 1641
              +   D +  Y+ Q+VQ L+Y++     +  ++L  A  +Q + H F W++K+      
Sbjct: 620  EKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFWHLKS------ 673

Query: 1642 EGHQKDPDIGDLLDQLVEEITGSLSGPAKDFYQREFDFFNKITNVSAIIKPYPKGDERKK 1701
            E H K   +      L+E    +     K    R+ +   K+ N++ I+K   K DE +K
Sbjct: 674  EMHNKT--VSQRFGLLLESYCRACGMYLKHL-NRQVEAMEKLINLTDILKQEKK-DETQK 729

Query: 1702 ACLSALSEVKVQP-------GCYLPSNPEAIVLDIDYKSGTPMQSAAKAPYLAKFKVKRC 1754
              +  L E   +P       G   P NP                    A  L   +++ C
Sbjct: 730  VQMKFLVEQMRRPDFMDALQGFLSPLNP--------------------AHQLGNLRLEEC 769

Query: 1755 GVSELEKEGLRCRSDSEDECSTQEADGQKISWQAAIFKVGDDCRQDMLALQIIDLFKNIF 1814
             +    K  L    ++ D  S       +I     IFK GDD RQDML LQII + +NI+
Sbjct: 770  RIMSSAKRPLWLNWENPDIMSELLFQNNEI-----IFKNGDDLRQDMLTLQIIRIMENIW 824

Query: 1815 QLVGLDLFVFPYRVVATAPGCGVIECIPDCTSRDQL----GRQTDFGMYDYFTRQYGDES 1870
            Q  GLDL + PY  ++     G+IE + +  +  Q+    G +       +   Q+  + 
Sbjct: 825  QNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDK 884

Query: 1871 TLA--FQQARYNFIRSMAAYSLLLFLLQIKDRHNGNIMLDKKGHIIHIDFGFMFESSP-- 1926
                 +  A   F RS A Y +  F+L I DRHN NIM+   G + HIDFG   +     
Sbjct: 885  NKGEIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKK 944

Query: 1927 -GGNLGWEPDIKLTDEMVMIMGGKMEAT---PFKWFMEMCVRGYLAVRPYMDAVVSLVTL 1982
             G      P +   D +++I  G  E T    F+ F EMC + YLA+R + +  ++L ++
Sbjct: 945  FGYKRERVPFVLTQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSM 1004

Query: 1983 MLDTGLPCFRG-QTIKLLKHRFSPNMTEREAANFIMK 2018
            ML +G+P  +    I  ++   + + TE+EA  + MK
Sbjct: 1005 MLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFMK 1041


>gi|21237725 phosphoinositide-3-kinase, catalytic, gamma polypeptide
            [Homo sapiens]
          Length = 1102

 Score =  137 bits (345), Expect = 1e-31
 Identities = 123/457 (26%), Positives = 218/457 (47%), Gaps = 40/457 (8%)

Query: 1581 VKVLRSFPPDAILFYIPQIVQALRYDKM--GYVREYILWAASKSQLLAHQFIWNMKTNIY 1638
            V+ L S   D +L Y+ Q+VQA++++      +  ++L    +++ + H   W +++ I 
Sbjct: 645  VQKLESLEDDDVLHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIA 704

Query: 1639 LDEEGHQKDPDIGDLLDQLVEEITGSLSGPAKDFYQREFDFFNKITNVSAIIKPYPKGDE 1698
                  Q+   I      L   + G  +    DF Q +      +  V+  IK      E
Sbjct: 705  QSRHYQQRFAVI------LEAYLRGCGTAMLHDFTQ-QVQVIEMLQKVTLDIKSLSA--E 755

Query: 1699 RKKACLSALSEVKVQPGCYLPSNPEAIVLDIDYKSGTPMQSAAKAPYLAKFKVKRCGVSE 1758
            +       +S++K +       N +   L   ++   P     KA  LA   +++C V  
Sbjct: 756  KYDVSSQVISQLKQKL-----ENLQNSQLPESFR--VPYDPGLKAGALA---IEKCKVMA 805

Query: 1759 LEKEGLRCRSDSEDECSTQEADGQKISWQAAIFKVGDDCRQDMLALQIIDLFKNIFQLVG 1818
             +K+ L      E +C+   A   +      IFK GDD RQDML LQI+ + ++I++   
Sbjct: 806  SKKKPLWL----EFKCADPTALSNETI--GIIFKHGDDLRQDMLILQILRIMESIWETES 859

Query: 1819 LDLFVFPYRVVATAPGCGVIECIPDCTSRDQLGRQT--DFGMY-DYFTRQYGDESTLA-- 1873
            LDL + PY  ++T    G+IE + D T+  ++ + T  + G + D     +  E +    
Sbjct: 860  LDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTGAFKDEVLNHWLKEKSPTEE 919

Query: 1874 -FQQARYNFIRSMAAYSLLLFLLQIKDRHNGNIMLDKKGHIIHIDFGFM---FESSPGGN 1929
             FQ A   F+ S A Y +  F+L I DRHN NIM+ + G++ HIDFG +   ++S  G N
Sbjct: 920  KFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNLFHIDFGHILGNYKSFLGIN 979

Query: 1930 LGWEPDIKLTDEMVMIMG--GKMEATPFKWFMEMCVRGYLAVRPYMDAVVSLVTLMLDTG 1987
                P + LT + + +MG  GK  +  F+ F ++CV+ YLA+R + + ++ L ++ML TG
Sbjct: 980  KERVPFV-LTPDFLFVMGTSGKKTSPHFQKFQDICVKAYLALRHHTNLLIILFSMMLMTG 1038

Query: 1988 LPCFRG-QTIKLLKHRFSPNMTEREAANFIMKVIQSC 2023
            +P     + I+ ++   +    E +A  + +  I+ C
Sbjct: 1039 MPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVC 1075


>gi|194353959 phosphoinositide-3-kinase, class 2 gamma polypeptide
            [Homo sapiens]
          Length = 1445

 Score =  136 bits (343), Expect = 2e-31
 Identities = 123/490 (25%), Positives = 220/490 (44%), Gaps = 59/490 (12%)

Query: 1554 WAPTDPPTGLSYFSSMYPPHPLTAQYGVKVLRSFPPDAILFYIPQIVQALRYD--KMGYV 1611
            W  + P   L   +S +P   +  +  V+ L +   D +L Y+PQ+VQA++++      +
Sbjct: 716  WTFSQPLEALGLLTSSFPDQEIR-KVAVQQLDNLLNDELLEYLPQLVQAVKFEWNLESPL 774

Query: 1612 REYILWAASKSQLLAHQFIWNMKTNIYLDEEGHQKDPDIGDLLDQLVEEITGSLSGPAKD 1671
             + +L  + +S  +AH+  W +K     + E + K         +L+  +         D
Sbjct: 775  VQLLLHRSLQSIQVAHRLYWLLKN---AENEAYFKS-----WYQKLLAALQFCAGKALND 826

Query: 1672 FYQREFDFFNKITNVSAIIKPYPKGDERK--KACLSALSEVKVQPG-CYLPSNPEAIVLD 1728
             + +E      + ++   +K       ++  K  +  L E       C+LP NP   +  
Sbjct: 827  EFSKEQKLIKILGDIGERVKSASDHQRQEVLKKEIGRLEEFFQDVNTCHLPLNPALCIKG 886

Query: 1729 IDYKSGTPMQSAAKAPYLAKFKVKRCGVSELEKEGLRCRSDSEDECSTQEADGQKISWQA 1788
            ID+ + +   S A        K+     + +                     G+ IS   
Sbjct: 887  IDHDACSYFTSNA-----LPLKITFINANPM---------------------GKNIS--- 917

Query: 1789 AIFKVGDDCRQDMLALQIIDLFKNIFQLVGLDLFVFPYRVVATAPGCGVIECIPDCTSRD 1848
             IFK GDD RQDML LQ+I +  NI+   GLD+ +  YR ++T    G+++ +PD  +  
Sbjct: 918  IIFKAGDDLRQDMLVLQLIQVMDNIWLQEGLDMQMIIYRCLSTGKDQGLVQMVPDAVTLA 977

Query: 1849 QLGRQT-------DFGMYDYFTRQYGDESTLAFQQARYNFIRSMAAYSLLLFLLQIKDRH 1901
            ++ R +       +  +  +F++   +     +++A  NF  S A + ++ F+L + DRH
Sbjct: 978  KIHRHSGLIGPLKENTIKKWFSQH--NHLKADYEKALRNFFYSCAGWCVVTFILGVCDRH 1035

Query: 1902 NGNIMLDKKGHIIHIDFG-FMFESSPGGNLGWE--PDIKLTDEMVMIMGGKMEATPFKWF 1958
            N NIML K GH+ HIDFG F+  +   G +  +  P I  ++    I  G      F+ F
Sbjct: 1036 NDNIMLTKSGHMFHIDFGKFLGHAQTFGGIKRDRAPFIFTSEMEYFITEGGKNPQHFQDF 1095

Query: 1959 MEMCVRGYLAVRPYMDAVVSLVTLMLDTGLPCFRG-QTIKLLKHRFSPNMTEREAANFIM 2017
            +E+C R Y  +R +   +++L+ +ML  GLP   G Q +K + +   P  T+ EA +   
Sbjct: 1096 VELCCRAYNIIRKHSQLLLNLLEMMLYAGLPELSGIQDLKYVYNNLRPQDTDLEATSHFT 1155

Query: 2018 KVIQ---SCF 2024
            K I+    CF
Sbjct: 1156 KKIKESLECF 1165


>gi|194097347 phosphoinositide-3-kinase, class 2 beta polypeptide
            [Homo sapiens]
          Length = 1634

 Score =  130 bits (328), Expect = 1e-29
 Identities = 128/516 (24%), Positives = 221/516 (42%), Gaps = 61/516 (11%)

Query: 1525 VSDVPEAIKFLVTWHTIDADAPELSHVLC-WAPTDPPTGLSYFSSMYPPHPLTAQYGVKV 1583
            VS +P  +    +W    A  P++  +L  W   +    L    + +P   +  +  V+ 
Sbjct: 850  VSSLPLVLASAPSWEW--ACLPDIYVLLKQWTHMNHQDALGLLHATFPDQEVR-RMAVQW 906

Query: 1584 LRSFPPDAILFYIPQIVQALRYDKM--GYVREYILWAASKSQLLAHQFIWNMKTNIYLDE 1641
            + S     +L Y+PQ+VQAL+Y+      +  ++L  A     + H F W +K  +    
Sbjct: 907  IGSLSDAELLDYLPQLVQALKYECYLDSPLVRFLLKRAVSDLRVTHYFFWLLKDGL---- 962

Query: 1642 EGHQKDPDIGDLLDQLVEEITGSLSGPAKDFYQREFDFFNKITNVSAIIKPYPKGDERKK 1701
                KD         L+  +        ++ + R+    N +  ++  ++       R+ 
Sbjct: 963  ----KDSQFSIRYQYLLAALLCCCGKGLREEFNRQCWLVNALAKLAQQVREAAPS-ARQG 1017

Query: 1702 ACLSALSEVK----VQPGCYLPSNPEAIVLDIDYKSGTPMQSAAKAPYLAKFKVKRCGVS 1757
               + L EVK    +   C LP +P  +V  I  +  +   S A    L+   V   G  
Sbjct: 1018 ILRTGLEEVKQFFALNGSCRLPLSPSLLVKGIVPRDCSYFNSNAVPLKLSFQNVDPLG-- 1075

Query: 1758 ELEKEGLRCRSDSEDECSTQEADGQKISWQAAIFKVGDDCRQDMLALQIIDLFKNIFQLV 1817
                E +R                        IFK GDD RQDML LQ+I +   I+   
Sbjct: 1076 ----ENIR-----------------------VIFKCGDDLRQDMLTLQMIRIMSKIWVQE 1108

Query: 1818 GLDLFVFPYRVVATAPGCGVIECIPDCTSRDQL-------GRQTDFGMYDYFTRQYGDES 1870
            GLD+ +  +R  +T  G G++E IP+  +  ++       G   D  + D+  +    E 
Sbjct: 1109 GLDMRMVIFRCFSTGRGRGMVEMIPNAETLRKIQVEHGVTGSFKDRPLADWLQKHNPGED 1168

Query: 1871 TLAFQQARYNFIRSMAAYSLLLFLLQIKDRHNGNIMLDKKGHIIHIDFG-FMFESSPGGN 1929
               +++A  NFI S A   +  ++L I DRHN NIML   GH+ HIDFG F+  +   GN
Sbjct: 1169 --EYEKAVENFIYSCAGCCVATYVLGICDRHNDNIMLKTTGHMFHIDFGRFLGHAQMFGN 1226

Query: 1930 LGWE--PDIKLTDEMVMIMGGKMEATPFKWFMEMCVRGYLAVRPYMDAVVSLVTLMLDTG 1987
            +  +  P +  +D   +I GG   ++ F  F+++C + Y  +R +    ++L+ LML  G
Sbjct: 1227 IKRDRAPFVFTSDMAYVINGGDKPSSRFHDFVDLCCQAYNLIRKHTHLFLNLLGLMLSCG 1286

Query: 1988 LPCFRG-QTIKLLKHRFSPNMTEREAANFIMKVIQS 2022
            +P     + +K +     P  TE  A  +  ++I+S
Sbjct: 1287 IPELSDLEDLKYVYDALRPQDTEANATTYFTRLIES 1322


>gi|157671929 phosphoinositide-3-kinase, class 2 alpha polypeptide
            [Homo sapiens]
          Length = 1686

 Score =  127 bits (320), Expect = 9e-29
 Identities = 121/486 (24%), Positives = 216/486 (44%), Gaps = 59/486 (12%)

Query: 1554 WAPTDPPTGLSYFSSMYPPHPLTAQYGVKVLRSFPPDAILFYIPQIVQALRYDKM--GYV 1611
            W    P   L    S +    + +   V  + +   D +   +PQ VQAL+Y+      +
Sbjct: 934  WPALYPLIALELLDSKFADQEVRS-LAVTWIEAISDDELTDLLPQFVQALKYEIYLNSSL 992

Query: 1612 REYILWAASKSQLLAHQFIWNMKTNIYLDEEGHQKDPDIGDLLDQLVEEITGSLSGPAKD 1671
             +++L  A  +  +AH   W +K  ++  +   + +  +G LL    + +   L    K 
Sbjct: 993  VQFLLSRALGNIQIAHNLYWLLKDALHDVQFSTRYEHVLGALLSVGGKRLREELLKQTK- 1051

Query: 1672 FYQREFDFFNKITNVSAIIKPYPKGDERKKACLSALSEVKV---QPGCYLPSNPEAIVLD 1728
              Q       K+   S        G  R+     ++  V+    +  C LP  P  +  +
Sbjct: 1052 LVQLLGGVAEKVRQAS--------GSARQVVLQRSMERVQSFFQKNKCRLPLKPSLVAKE 1103

Query: 1729 IDYKSGTPMQSAAKAPYLAKFKVKRCGVSELEKEGLRCRSDSEDECSTQEADGQKISWQA 1788
            ++ KS +   S A        KV       +                     G++I+   
Sbjct: 1104 LNIKSCSFFSSNA-----VPLKVTMVNADPM---------------------GEEIN--- 1134

Query: 1789 AIFKVGDDCRQDMLALQIIDLFKNIFQLVGLDLFVFPYRVVATAPGCGVIECIPDCTSRD 1848
             +FKVG+D RQDMLALQ+I +   I+   GLDL +  ++ ++T    G++E +P   +  
Sbjct: 1135 VMFKVGEDLRQDMLALQMIKIMDKIWLKEGLDLRMVIFKCLSTGRDRGMVELVPASDTLR 1194

Query: 1849 QLGRQTDFGMYDYFT--------RQYGDESTLAFQQARYNFIRSMAAYSLLLFLLQIKDR 1900
            ++  Q ++G+   F         R+Y + S   +++A  NFI S A   +  ++L I DR
Sbjct: 1195 KI--QVEYGVTGSFKDKPLAEWLRKY-NPSEEEYEKASENFIYSCAGCCVATYVLGICDR 1251

Query: 1901 HNGNIMLDKKGHIIHIDFG-FMFESSPGGNLGWE--PDIKLTDEMVMIMGGKMEATPFKW 1957
            HN NIML   GH+ HIDFG F+  +   G+   +  P +  +D   +I GG+     F+ 
Sbjct: 1252 HNDNIMLRSTGHMFHIDFGKFLGHAQMFGSFKRDRAPFVLTSDMAYVINGGEKPTIRFQL 1311

Query: 1958 FMEMCVRGYLAVRPYMDAVVSLVTLMLDTGLPCFRG-QTIKLLKHRFSPNMTEREAANFI 2016
            F+++C + Y  +R   +  ++L++LM+ +GLP     Q +K ++    P  T+ EA  F 
Sbjct: 1312 FVDLCCQAYNLIRKQTNLFLNLLSLMIPSGLPELTSIQDLKYVRDALQPQTTDAEATIFF 1371

Query: 2017 MKVIQS 2022
             ++I+S
Sbjct: 1372 TRLIES 1377


>gi|34761064 catalytic phosphatidylinositol 3-kinase 3 [Homo sapiens]
          Length = 887

 Score =  116 bits (291), Expect = 2e-25
 Identities = 72/237 (30%), Positives = 125/237 (52%), Gaps = 13/237 (5%)

Query: 1790 IFKVGDDCRQDMLALQIIDLFKNIFQLVGLDLFVFPYRVVATAPGCGVIECIPDCTSRDQ 1849
            IFK GDD RQD L LQII L   + +   LDL + PY+V+AT+   G ++ I      + 
Sbjct: 634  IFKHGDDLRQDQLILQIISLMDKLLRKENLDLKLTPYKVLATSTKHGFMQFIQSVPVAEV 693

Query: 1850 LGRQTDFGMYDYFTRQYGDES---TLAFQQARYNFIRSMAAYSLLLFLLQIKDRHNGNIM 1906
            L  +   G    F R+Y            +    +++S A Y ++ ++L + DRH  N++
Sbjct: 694  LDTE---GSIQNFFRKYAPSENGPNGISAEVMDTYVKSCAGYCVITYILGVGDRHLDNLL 750

Query: 1907 LDKKGHIIHIDFGFMFESSPGGNLGWEPDIKLTDEMVMIMGGKMEATPFKWFMEMCVRGY 1966
            L K G + HIDFG++    P       P +KL  EMV  MGG  ++  ++ F + C   +
Sbjct: 751  LTKTGKLFHIDFGYILGRDP---KPLPPPMKLNKEMVEGMGG-TQSEQYQEFRKQCYTAF 806

Query: 1967 LAVRPYMDAVVSLVTLMLDTGLPCFR---GQTIKLLKHRFSPNMTEREAANFIMKVI 2020
            L +R Y + +++L +LM+D  +P       +T+K ++ +F  ++++ EA +++  +I
Sbjct: 807  LHLRRYSNLILNLFSLMVDANIPDIALEPDKTVKKVQDKFRLDLSDEEAVHYMQSLI 863



 Score = 39.3 bits (90), Expect = 0.040
 Identities = 30/106 (28%), Positives = 44/106 (41%), Gaps = 3/106 (2%)

Query: 1533 KFL--VTWHTIDADAPELSHVLCWAPTDPPTGLSYFSSMYPPHPLTAQYGVKVLRSFPPD 1590
            KFL  V W         L  +  W P D    L   SS Y  +P   +Y V  LR    +
Sbjct: 332  KFLKCVNWDLPQEAKQALELLGKWKPMDVEDSLELLSSHYT-NPTVRRYAVARLRQADDE 390

Query: 1591 AILFYIPQIVQALRYDKMGYVREYILWAASKSQLLAHQFIWNMKTN 1636
             +L Y+ Q+VQAL+Y+    ++  +      SQ    + + N   N
Sbjct: 391  DLLMYLLQLVQALKYENFDDIKNGLEPTKKDSQSSVSENVSNSGIN 436


>gi|5453894 catalytic phosphatidylinositol 3-kinase beta [Homo
            sapiens]
          Length = 1070

 Score =  115 bits (287), Expect = 6e-25
 Identities = 123/501 (24%), Positives = 204/501 (40%), Gaps = 67/501 (13%)

Query: 1536 VTWHTIDADAPELSHVLCWAPTDPPTGLSYFSSMYPPHPLTAQYGVKVLRSFPPDAILFY 1595
            + W+ ++  A   + +  W    P   L      YP      +Y V  LR    + +  Y
Sbjct: 580  IKWNKLEDVAQLQALLQIWPKLPPREALELLDFNYPDQ-YVREYAVGCLRQMSDEELSQY 638

Query: 1596 IPQIVQALRYDKM--GYVREYILWAASKSQLLAHQFIWNMKTNIYLDEEGHQKDPDIGDL 1653
            + Q+VQ L+Y+      +  ++L  A  ++ +     W++++ +++     Q     G +
Sbjct: 639  LLQLVQVLKYEPFLDCALSRFLLERALGNRRIGQFLFWHLRSEVHIPAVSVQ----FGVI 694

Query: 1654 LDQLVEEITGSLSGPAKDFYQREFDFFNKITNVSAIIK------PYPKGDERKKACLSAL 1707
            L+       G +   +K     + +  NK+  ++++IK         KG E    CL   
Sbjct: 695  LEAYCRGSVGHMKVLSK-----QVEALNKLKTLNSLIKLNAVKLNRAKGKEAMHTCLKQS 749

Query: 1708 SEVKVQPGCYLPSNPEAIVLDIDYKSGTPMQSAAKAPYLAKFKVKRCGVSELEKEGLRCR 1767
            +  +       P NP  I+ ++  +    M S  K  +L  +  K  G   +        
Sbjct: 750  AYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPLWLV-YNNKVFGEDSV-------- 800

Query: 1768 SDSEDECSTQEADGQKISWQAAIFKVGDDCRQDMLALQIIDLFKNIFQLVGLDLFVFPYR 1827
                                  IFK GDD RQDML LQ++ L   +++  GLDL + PY 
Sbjct: 801  --------------------GVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG 840

Query: 1828 VVATAPGCGVIECIPDC-TSRDQLGRQTDFGMYDYFTR----------QYGDESTLAFQQ 1876
             +AT    G+IE +    T  D     ++      F +            GD+   A ++
Sbjct: 841  CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE 900

Query: 1877 ARYNFIRSMAAYSLLLFLLQIKDRHNGNIMLDKKGHIIHIDFGFM---FESSPGGNLGWE 1933
                F  S A Y +  ++L I DRH+ NIM+ K G + HIDFG +   F+S  G      
Sbjct: 901  ----FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERV 956

Query: 1934 PDIKLTDEMVMIMGGKMEAT-PFKWFMEMCVRGYLAVRPYMDAVVSLVTLMLDTGLPCFR 1992
            P I   D + +I  GK   T  F  F + C   YL +R + +  ++L  LML  GLP   
Sbjct: 957  PFILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELT 1016

Query: 1993 G-QTIKLLKHRFSPNMTEREA 2012
              + I+ LK   +   +E EA
Sbjct: 1017 SVKDIQYLKDSLALGKSEEEA 1037


>gi|156564405 catalytic phosphatidylinositol 3-kinase delta [Homo
            sapiens]
          Length = 1044

 Score =  112 bits (279), Expect = 5e-24
 Identities = 123/506 (24%), Positives = 205/506 (40%), Gaps = 59/506 (11%)

Query: 1529 PEAIK--FLVTWHTIDADAPELSHVLCWAPTDPPTGLSYFSSMYPPHPLTAQYGVKVLRS 1586
            PEA+    LVT      D  ++ ++LC  P  P            P      + +K LR 
Sbjct: 543  PEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKSLRK 602

Query: 1587 FPPDAILFYIPQIVQALRYDKM--GYVREYILWAASKSQLLAHQFIWNMKTNIYLDEEGH 1644
               D +  Y+ Q+VQ L+Y+      + +++L  A  ++ + H   W++++ +++     
Sbjct: 603  LTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSVAL 662

Query: 1645 QKDPDIGDLLDQLVEEITGSLSGPAKDFYQ-REFDFFNKITNVSAIIKPYPKGDERKKAC 1703
            +     G +L+      T  +    K      +    N    +S+   P P+  E    C
Sbjct: 663  R----FGLILEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKLSSQKTPKPQTKELMHLC 718

Query: 1704 LSALSEVKVQPGCYLPSNPEAIVLDIDYKSGTPMQSAAKAPYLAKFKVKRCGVSELEKEG 1763
            +   + ++       P +P  ++ ++  +  T M S  K  ++                 
Sbjct: 719  MRQEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMY--------------- 763

Query: 1764 LRCRSDSEDECSTQEADGQKISWQAAIFKVGDDCRQDMLALQIIDLFKNIFQLVGLDLFV 1823
                  S +E  +  + G        IFK GDD RQDML LQ+I L   +++  GLDL +
Sbjct: 764  ------SNEEAGSGGSVG-------IIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRM 810

Query: 1824 FPYRVVATAPGCGVIECI--PDCTSRDQLGRQTDFGMYDYFTRQYGDESTL--------- 1872
             PY  + T    G+IE +   D  +  QL +          T  +  ++ L         
Sbjct: 811  TPYGCLPTGDRTGLIEVVLRSDTIANIQLNKSNMAA-----TAAFNKDALLNWLKSKNPG 865

Query: 1873 -AFQQARYNFIRSMAAYSLLLFLLQIKDRHNGNIMLDKKGHIIHIDFGFM---FESSPGG 1928
             A  +A   F  S A Y +  ++L I DRH+ NIM+ + G + HIDFG     F++  G 
Sbjct: 866  EALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNFKTKFGI 925

Query: 1929 NLGWEPDIKLTDEMVMIMGGKM-EATPFKWFMEMCVRGYLAVRPYMDAVVSLVTLMLDTG 1987
            N    P I   D + +I  GK   +  F+ F   C R Y  +R +    + L  LM   G
Sbjct: 926  NRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAG 985

Query: 1988 LPCFR-GQTIKLLKHRFSPNMTEREA 2012
            LP     + I+ LK   +   TE EA
Sbjct: 986  LPELSCSKDIQYLKDSLALGKTEEEA 1011


>gi|4826730 FK506 binding protein 12-rapamycin associated protein 1
            [Homo sapiens]
          Length = 2549

 Score = 48.1 bits (113), Expect = 9e-05
 Identities = 23/47 (48%), Positives = 33/47 (70%), Gaps = 1/47 (2%)

Query: 1878 RYNFIRSMAAYSLLLFLLQIKDRHNGNIMLDK-KGHIIHIDFGFMFE 1923
            R N+ RS+A  S++ ++L + DRH  N+MLD+  G I+HIDFG  FE
Sbjct: 2317 RTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFE 2363


>gi|157266317 ataxia telangiectasia and Rad3 related protein [Homo
            sapiens]
          Length = 2644

 Score = 43.9 bits (102), Expect = 0.002
 Identities = 26/90 (28%), Positives = 46/90 (51%), Gaps = 3/90 (3%)

Query: 1859 YDYFTRQYGDESTLAFQQARYNFIRSMAAYSLLLFLLQIKDRHNGNIMLDK-KGHIIHID 1917
            +++F R + D ++  +  +R  + RS A  S++ ++L + DRH  NI+ D   G  +H+D
Sbjct: 2437 HEWFLRTFPDPTS--WYSSRSAYCRSTAVMSMVGYILGLGDRHGENILFDSLTGECVHVD 2494

Query: 1918 FGFMFESSPGGNLGWEPDIKLTDEMVMIMG 1947
            F  +F       +      +LT  MV  MG
Sbjct: 2495 FNCLFNKGETFEVPEIVPFRLTHNMVNGMG 2524


>gi|169165926 PREDICTED: similar to ataxia telangiectasia and Rad3
            related protein, partial [Homo sapiens]
          Length = 386

 Score = 43.9 bits (102), Expect = 0.002
 Identities = 26/90 (28%), Positives = 46/90 (51%), Gaps = 3/90 (3%)

Query: 1859 YDYFTRQYGDESTLAFQQARYNFIRSMAAYSLLLFLLQIKDRHNGNIMLDK-KGHIIHID 1917
            +++F R + D ++  +  +R  + RS A  S++ ++L + DRH  NI+ D   G  +H+D
Sbjct: 179  HEWFLRTFPDPTS--WYSSRSAYCRSTAVMSMVGYILGLGDRHGENILFDSLTGECVHVD 236

Query: 1918 FGFMFESSPGGNLGWEPDIKLTDEMVMIMG 1947
            F  +F       +      +LT  MV  MG
Sbjct: 237  FNCLFNKGETFEVPEIVPFRLTHNMVNGMG 266


>gi|20336199 ataxia telangiectasia mutated isoform 2 [Homo sapiens]
          Length = 1708

 Score = 38.1 bits (87), Expect = 0.089
 Identities = 33/132 (25%), Positives = 68/132 (51%), Gaps = 13/132 (9%)

Query: 1858 MYDYFTRQYGDESTLAFQQARYNFIRSMAAYSLLLFLLQIKDRHNGNIML-DKKGHIIHI 1916
            ++ YF  +   +  + F++ R  + RS+A  S++ ++L + DRH  NI++ ++   ++HI
Sbjct: 1482 VFRYFCMEKFLDPAIWFEK-RLAYTRSVATSSIVGYILGLGDRHVQNILINEQSAELVHI 1540

Query: 1917 DFGFMFESSPGGNLGWEPD---IKLTDEMVMIMG-GKMEATPFKWFMEMCVRGYLAVRPY 1972
            D G  FE    G +   P+    +LT ++V  MG   +E      F   C +    +R  
Sbjct: 1541 DLGVAFEQ---GKILPTPETVPFRLTRDIVDGMGITGVEGV----FRRCCEKTMEVMRNS 1593

Query: 1973 MDAVVSLVTLML 1984
             + ++++V ++L
Sbjct: 1594 QETLLTIVEVLL 1605


>gi|71902540 ataxia telangiectasia mutated isoform 1 [Homo sapiens]
          Length = 3056

 Score = 38.1 bits (87), Expect = 0.089
 Identities = 33/132 (25%), Positives = 68/132 (51%), Gaps = 13/132 (9%)

Query: 1858 MYDYFTRQYGDESTLAFQQARYNFIRSMAAYSLLLFLLQIKDRHNGNIML-DKKGHIIHI 1916
            ++ YF  +   +  + F++ R  + RS+A  S++ ++L + DRH  NI++ ++   ++HI
Sbjct: 2830 VFRYFCMEKFLDPAIWFEK-RLAYTRSVATSSIVGYILGLGDRHVQNILINEQSAELVHI 2888

Query: 1917 DFGFMFESSPGGNLGWEPD---IKLTDEMVMIMG-GKMEATPFKWFMEMCVRGYLAVRPY 1972
            D G  FE    G +   P+    +LT ++V  MG   +E      F   C +    +R  
Sbjct: 2889 DLGVAFEQ---GKILPTPETVPFRLTRDIVDGMGITGVEGV----FRRCCEKTMEVMRNS 2941

Query: 1973 MDAVVSLVTLML 1984
             + ++++V ++L
Sbjct: 2942 QETLLTIVEVLL 2953


>gi|169218268 PREDICTED: similar to Serine-protein kinase ATM, partial
            [Homo sapiens]
          Length = 2934

 Score = 38.1 bits (87), Expect = 0.089
 Identities = 33/132 (25%), Positives = 68/132 (51%), Gaps = 13/132 (9%)

Query: 1858 MYDYFTRQYGDESTLAFQQARYNFIRSMAAYSLLLFLLQIKDRHNGNIML-DKKGHIIHI 1916
            ++ YF  +   +  + F++ R  + RS+A  S++ ++L + DRH  NI++ ++   ++HI
Sbjct: 2708 VFRYFCMEKFLDPAIWFEK-RLAYTRSVATSSIVGYILGLGDRHVQNILINEQSAELVHI 2766

Query: 1917 DFGFMFESSPGGNLGWEPD---IKLTDEMVMIMG-GKMEATPFKWFMEMCVRGYLAVRPY 1972
            D G  FE    G +   P+    +LT ++V  MG   +E      F   C +    +R  
Sbjct: 2767 DLGVAFEQ---GKILPTPETVPFRLTRDIVDGMGITGVEGV----FRRCCEKTMEVMRNS 2819

Query: 1973 MDAVVSLVTLML 1984
             + ++++V ++L
Sbjct: 2820 QETLLTIVEVLL 2831


>gi|62243658 PI-3-kinase-related kinase SMG-1 [Homo sapiens]
          Length = 3661

 Score = 38.1 bits (87), Expect = 0.089
 Identities = 17/69 (24%), Positives = 37/69 (53%), Gaps = 1/69 (1%)

Query: 1880 NFIRSMAAYSLLLFLLQIKDRHNGNIMLD-KKGHIIHIDFGFMFESSPGGNLGWEPDIKL 1938
            ++ RS A  S++ +++ + DRH  N+++D   G ++HID+   FE      +  +   ++
Sbjct: 2316 SYARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCFEKGKSLRVPEKVPFRM 2375

Query: 1939 TDEMVMIMG 1947
            T  +   +G
Sbjct: 2376 TQNIETALG 2384


>gi|226246554 hypothetical protein LOC643677 [Homo sapiens]
          Length = 7081

 Score = 35.8 bits (81), Expect = 0.44
 Identities = 28/83 (33%), Positives = 40/83 (48%), Gaps = 3/83 (3%)

Query: 1635 TNIYLDEEGHQKDPDIGDLLDQLVE--EITGSLSGPAKDFYQREFDFFNKITNVSAIIKP 1692
            T  YL E  HQK  + G+  D +    +IT  +   AKD+ Q++ D   KI+    I+ P
Sbjct: 4113 TRYYLPELSHQKSSEAGEKADGVASKGDITIKVQ-KAKDYMQQKEDDEVKISAKKDIMHP 4171

Query: 1693 YPKGDERKKACLSALSEVKVQPG 1715
              KG + KKA    L     +PG
Sbjct: 4172 EDKGLKAKKALSQDLPLNTKEPG 4194


>gi|239756039 PREDICTED: hypothetical protein LOC643677 [Homo sapiens]
          Length = 6929

 Score = 35.8 bits (81), Expect = 0.44
 Identities = 28/83 (33%), Positives = 40/83 (48%), Gaps = 3/83 (3%)

Query: 1635 TNIYLDEEGHQKDPDIGDLLDQLVE--EITGSLSGPAKDFYQREFDFFNKITNVSAIIKP 1692
            T  YL E  HQK  + G+  D +    +IT  +   AKD+ Q++ D   KI+    I+ P
Sbjct: 4042 TRYYLPELSHQKSSEAGEKADGVASKGDITIKVQ-KAKDYMQQKEDDEVKISAKKDIMHP 4100

Query: 1693 YPKGDERKKACLSALSEVKVQPG 1715
              KG + KKA    L     +PG
Sbjct: 4101 EDKGLKAKKALSQDLPLNTKEPG 4123


>gi|239750569 PREDICTED: hypothetical protein LOC643677 [Homo sapiens]
          Length = 6929

 Score = 35.8 bits (81), Expect = 0.44
 Identities = 28/83 (33%), Positives = 40/83 (48%), Gaps = 3/83 (3%)

Query: 1635 TNIYLDEEGHQKDPDIGDLLDQLVE--EITGSLSGPAKDFYQREFDFFNKITNVSAIIKP 1692
            T  YL E  HQK  + G+  D +    +IT  +   AKD+ Q++ D   KI+    I+ P
Sbjct: 4042 TRYYLPELSHQKSSEAGEKADGVASKGDITIKVQ-KAKDYMQQKEDDEVKISAKKDIMHP 4100

Query: 1693 YPKGDERKKACLSALSEVKVQPG 1715
              KG + KKA    L     +PG
Sbjct: 4101 EDKGLKAKKALSQDLPLNTKEPG 4123


>gi|239744870 PREDICTED: hypothetical protein LOC643677 [Homo sapiens]
          Length = 6929

 Score = 35.8 bits (81), Expect = 0.44
 Identities = 28/83 (33%), Positives = 40/83 (48%), Gaps = 3/83 (3%)

Query: 1635 TNIYLDEEGHQKDPDIGDLLDQLVE--EITGSLSGPAKDFYQREFDFFNKITNVSAIIKP 1692
            T  YL E  HQK  + G+  D +    +IT  +   AKD+ Q++ D   KI+    I+ P
Sbjct: 4042 TRYYLPELSHQKSSEAGEKADGVASKGDITIKVQ-KAKDYMQQKEDDEVKISAKKDIMHP 4100

Query: 1693 YPKGDERKKACLSALSEVKVQPG 1715
              KG + KKA    L     +PG
Sbjct: 4101 EDKGLKAKKALSQDLPLNTKEPG 4123


>gi|19924149 toll-like receptor 4 precursor [Homo sapiens]
          Length = 839

 Score = 34.3 bits (77), Expect = 1.3
 Identities = 31/147 (21%), Positives = 62/147 (42%), Gaps = 4/147 (2%)

Query: 243 FSTISSSFSVSPLFNGVTYKEFNIPLEMLRELLNLVKKIVEEAVLKSLDAIVASVMEANP 302
           FST +   S +PL +  +Y  F+ P   + +L     + +E+   +SL  +   ++  NP
Sbjct: 54  FSTKNLDLSFNPLRHLGSYSFFSFPELQVLDLSRCEIQTIEDGAYQSLSHLSTLILTGNP 113

Query: 303 SADLYYTSFSDPLYLTMFKMLRDTLYYMKDLPTSFVKEIHDFVLEQFNTSQGELQKILHD 362
              L   +FS    L     +   L  +++ P   +K + +  +        +L +   +
Sbjct: 114 IQSLALGAFSGLSSLQKLVAVETNLASLENFPIGHLKTLKELNVAHNLIQSFKLPEYFSN 173

Query: 363 ADRI-HNELSPLKLRCQANAACVDLMV 388
              + H +LS  K++   +  C DL V
Sbjct: 174 LTNLEHLDLSSNKIQ---SIYCTDLRV 197


>gi|126032350 protein kinase, DNA-activated, catalytic polypeptide
            isoform 2 [Homo sapiens]
          Length = 4097

 Score = 34.3 bits (77), Expect = 1.3
 Identities = 43/168 (25%), Positives = 60/168 (35%), Gaps = 32/168 (19%)

Query: 1790 IFKVGDDCRQDMLALQIIDLFKNIF-QLVGLDLFVFPYRVVATAPGCGVIECIPDCTSRD 1848
            + K G+D RQD    Q+  +   I  Q           R  +  P        P C  +D
Sbjct: 3751 LVKGGEDLRQDQRVEQLFQVMNGILAQDSACSQRALQLRTYSVVPMTSSDPRAPPCEYKD 3810

Query: 1849 QLGRQT---DFGMY-------------------------DYFTRQYGDESTL--AFQQAR 1878
             L + +   D G Y                         D   R +   ST   AF   R
Sbjct: 3811 WLTKMSGKHDVGAYMLMYKGANRTETVTSFRKRESKVPADLLKRAFVRMSTSPEAFLALR 3870

Query: 1879 YNFIRSMAAYSLLLFLLQIKDRHNGNIMLD-KKGHIIHIDFGFMFESS 1925
             +F  S A   +  ++L I DRH  N M+  + G +I IDFG  F S+
Sbjct: 3871 SHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSA 3918


>gi|113430845 PREDICTED: similar to protein kinase, DNA-activated,
            catalytic polypeptide [Homo sapiens]
          Length = 4096

 Score = 34.3 bits (77), Expect = 1.3
 Identities = 43/168 (25%), Positives = 60/168 (35%), Gaps = 32/168 (19%)

Query: 1790 IFKVGDDCRQDMLALQIIDLFKNIF-QLVGLDLFVFPYRVVATAPGCGVIECIPDCTSRD 1848
            + K G+D RQD    Q+  +   I  Q           R  +  P        P C  +D
Sbjct: 3750 LVKGGEDLRQDQRVEQLFQVMNGILAQDSACSQRALQLRTYSVVPMTSSDPRAPPCEYKD 3809

Query: 1849 QLGRQT---DFGMY-------------------------DYFTRQYGDESTL--AFQQAR 1878
             L + +   D G Y                         D   R +   ST   AF   R
Sbjct: 3810 WLTKMSGKHDVGAYMLMYKGANRTETVTSFRKRESKVPADLLKRAFVRMSTSPEAFLALR 3869

Query: 1879 YNFIRSMAAYSLLLFLLQIKDRHNGNIMLD-KKGHIIHIDFGFMFESS 1925
             +F  S A   +  ++L I DRH  N M+  + G +I IDFG  F S+
Sbjct: 3870 SHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSA 3917


>gi|171184451 centrosome-associated protein 350 [Homo sapiens]
          Length = 3117

 Score = 34.3 bits (77), Expect = 1.3
 Identities = 26/110 (23%), Positives = 45/110 (40%), Gaps = 5/110 (4%)

Query: 1366 SQLVPPDNQDTRSNLDITVGSRQQATQGWINTYPLSSGMSTISKKSGMSKKTNRGSQLHK 1425
            S+L    + DT+ N   + G     T+      P    +S+    S M K     S++ +
Sbjct: 1801 SKLDSHSDDDTKDNKATSPGPTDLETRS-----PSPISISSSETSSIMQKLKKMRSRMDE 1855

Query: 1426 YYMKRRTLLLSLLATEIERLITWYNPLSAPELELDQAGENSVANWRSKYI 1475
             ++ +R   L       E L+ W   L A E E+ Q  + ++A W  + I
Sbjct: 1856 KFLTKREQKLMQRRQHAEELLEWKRRLDAEEAEIRQMEKQALAAWDKELI 1905


>gi|194394141 nucleolar preribosomal-associated protein 1 [Homo
           sapiens]
          Length = 2271

 Score = 33.9 bits (76), Expect = 1.7
 Identities = 31/103 (30%), Positives = 45/103 (43%), Gaps = 15/103 (14%)

Query: 21  IALGIFLIESDLQHKDCVVPYLLRLLK-------GLP---KVYWVEESTARKGRGALPVA 70
           +AL + L   D     C+VP   +L +        +P   +  W+ ++       ALP+A
Sbjct: 828 LALCLLLQAYDKLEPPCLVPCCQQLSRFNRYYSLWIPEQAREAWLLQAQGSPSPPALPLA 887

Query: 71  ESFSFCLVTLLSDVAYRDPSLRDEILEVLLQVLHVLLGMCQAL 113
            SF     T L   AY   +LRDE ++V LQ     L M Q L
Sbjct: 888 SSF-----TALLQAAYESQALRDEHIQVQLQATMPHLSMQQVL 925


>gi|59710093 G-protein coupled receptor 112 [Homo sapiens]
          Length = 3080

 Score = 33.1 bits (74), Expect = 2.9
 Identities = 31/163 (19%), Positives = 64/163 (39%), Gaps = 3/163 (1%)

Query: 151  FPKIPPHSLRVLEELEGVRRRSFNDFRSILPSNLLTVCQEGTLKRKTSSVSSISQVSPER 210
            FP   P S+ V +++  +        R+ + +N  TV    +  RKT S S+        
Sbjct: 2084 FPTSLPMSINVTDDIVYISTHPEASSRTTITANPRTVSHPSSFSRKTMSPSTTDHTLSVG 2143

Query: 211  GMPPPSSPGGSAFHYFEASCLPDGTALEPEYYFSTISSSFSVSPLFNGVTYK--EFNIPL 268
             MP PSS   S+++    +  P  T + P+    ++ +  + +    G ++      +  
Sbjct: 2144 AMPLPSSTITSSWNRIPTASSP-STLIIPKPTLDSLLNIMTTTSTVPGASFPLISTGVTY 2202

Query: 269  EMLRELLNLVKKIVEEAVLKSLDAIVASVMEANPSADLYYTSF 311
                 + + +    E   L S  + +++    +P+A     SF
Sbjct: 2203 PFTATVSSPISSFFETTWLDSTPSFLSTEASTSPTATKSTVSF 2245


>gi|13654237 protein kinase, DNA-activated, catalytic polypeptide
            isoform 1 [Homo sapiens]
          Length = 4128

 Score = 32.7 bits (73), Expect = 3.7
 Identities = 21/54 (38%), Positives = 29/54 (53%), Gaps = 1/54 (1%)

Query: 1873 AFQQARYNFIRSMAAYSLLLFLLQIKDRHNGNIMLD-KKGHIIHIDFGFMFESS 1925
            AF   R +F  S A   +  ++L I DRH  N M+  + G +I IDFG  F S+
Sbjct: 3896 AFLALRSHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSA 3949


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 76,852,369
Number of Sequences: 37866
Number of extensions: 3428243
Number of successful extensions: 8770
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 24
Number of HSP's that attempted gapping in prelim test: 8634
Number of HSP's gapped (non-prelim): 135
length of query: 2044
length of database: 18,247,518
effective HSP length: 118
effective length of query: 1926
effective length of database: 13,779,330
effective search space: 26538989580
effective search space used: 26538989580
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.