Guide to the Human Genome
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Search of human proteins with 154800441

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|154800441 proline-rich protein HaeIII subfamily 1 [Homo
sapiens]
         (166 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|154800441 proline-rich protein HaeIII subfamily 1 [Homo sapiens]   365   e-101
gi|158966674 proline-rich protein HaeIII subfamily 2 [Homo sapiens]   360   e-100
gi|4826944 proline-rich protein HaeIII subfamily 2 [Homo sapiens]     360   e-100
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...   195   2e-50
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]    194   4e-50
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H...   184   4e-47
gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2 pre...   171   2e-43
gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Ho...   169   1e-42
gi|41349486 proline-rich protein BstNI subfamily 1 isoform 3 pre...   163   7e-41
gi|154448886 proline rich 4 (lacrimal) isoform 2 [Homo sapiens]        96   1e-20
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ...    80   1e-15
gi|7706501 WW domain binding protein 11 [Homo sapiens]                 79   2e-15
gi|19924099 synapsin I isoform Ia [Homo sapiens]                       76   2e-14
gi|19924097 synapsin I isoform Ib [Homo sapiens]                       76   2e-14
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ...    74   7e-14
gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]               74   7e-14
gi|57165375 glutamate receptor, ionotropic, N-methyl D-aspartate...    73   1e-13
gi|57165373 glutamate receptor, ionotropic, N-methyl D-aspartate...    73   1e-13
gi|154448882 proline rich 4 (lacrimal) isoform 1 [Homo sapiens]        73   1e-13
gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]             71   5e-13
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    71   5e-13
gi|38150007 small nuclear ribonucleoprotein polypeptide B/B' iso...    70   6e-13
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]                70   8e-13
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap...    69   2e-12
gi|50428940 mediator complex subunit 25 [Homo sapiens]                 68   3e-12
gi|50511941 EMI domain containing 1 [Homo sapiens]                     66   1e-11
gi|56117846 synovial sarcoma translocation, chromosome 18 isofor...    65   3e-11
gi|56117844 synovial sarcoma translocation, chromosome 18 isofor...    65   3e-11
gi|42544123 splicing factor 1 isoform 3 [Homo sapiens]                 65   3e-11
gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]                 65   3e-11

>gi|154800441 proline-rich protein HaeIII subfamily 1 [Homo sapiens]
          Length = 166

 Score =  365 bits (936), Expect = e-101
 Identities = 166/166 (100%), Positives = 166/166 (100%)

Query: 1   MLLILLSVALLAFSSAQDLNEDVSQEDVPLVISDGGDSEQFLDEERQGPPLGGQQSQPSA 60
           MLLILLSVALLAFSSAQDLNEDVSQEDVPLVISDGGDSEQFLDEERQGPPLGGQQSQPSA
Sbjct: 1   MLLILLSVALLAFSSAQDLNEDVSQEDVPLVISDGGDSEQFLDEERQGPPLGGQQSQPSA 60

Query: 61  GDGNQDDGPQQGPPQQGGQQQQGPPPPQGKPQGPPQQGGHPPPPQGRPQGPPQQGGHPRP 120
           GDGNQDDGPQQGPPQQGGQQQQGPPPPQGKPQGPPQQGGHPPPPQGRPQGPPQQGGHPRP
Sbjct: 61  GDGNQDDGPQQGPPQQGGQQQQGPPPPQGKPQGPPQQGGHPPPPQGRPQGPPQQGGHPRP 120

Query: 121 PRGRPQGPPQQGGHQQGPPPPPPGKPQGPPPQGGRPQGPPQGQSPQ 166
           PRGRPQGPPQQGGHQQGPPPPPPGKPQGPPPQGGRPQGPPQGQSPQ
Sbjct: 121 PRGRPQGPPQQGGHQQGPPPPPPGKPQGPPPQGGRPQGPPQGQSPQ 166


>gi|158966674 proline-rich protein HaeIII subfamily 2 [Homo sapiens]
          Length = 166

 Score =  360 bits (924), Expect = e-100
 Identities = 163/166 (98%), Positives = 166/166 (100%)

Query: 1   MLLILLSVALLAFSSAQDLNEDVSQEDVPLVISDGGDSEQFLDEERQGPPLGGQQSQPSA 60
           MLLILLSVALLAFSSAQDL+EDVSQEDVPLVISDGGDSEQF+DEERQGPPLGGQQSQPSA
Sbjct: 1   MLLILLSVALLAFSSAQDLDEDVSQEDVPLVISDGGDSEQFIDEERQGPPLGGQQSQPSA 60

Query: 61  GDGNQDDGPQQGPPQQGGQQQQGPPPPQGKPQGPPQQGGHPPPPQGRPQGPPQQGGHPRP 120
           GDGNQ+DGPQQGPPQQGGQQQQGPPPPQGKPQGPPQQGGHPPPPQGRPQGPPQQGGHPRP
Sbjct: 61  GDGNQNDGPQQGPPQQGGQQQQGPPPPQGKPQGPPQQGGHPPPPQGRPQGPPQQGGHPRP 120

Query: 121 PRGRPQGPPQQGGHQQGPPPPPPGKPQGPPPQGGRPQGPPQGQSPQ 166
           PRGRPQGPPQQGGHQQGPPPPPPGKPQGPPPQGGRPQGPPQGQSPQ
Sbjct: 121 PRGRPQGPPQQGGHQQGPPPPPPGKPQGPPPQGGRPQGPPQGQSPQ 166


>gi|4826944 proline-rich protein HaeIII subfamily 2 [Homo sapiens]
          Length = 166

 Score =  360 bits (924), Expect = e-100
 Identities = 163/166 (98%), Positives = 166/166 (100%)

Query: 1   MLLILLSVALLAFSSAQDLNEDVSQEDVPLVISDGGDSEQFLDEERQGPPLGGQQSQPSA 60
           MLLILLSVALLAFSSAQDL+EDVSQEDVPLVISDGGDSEQF+DEERQGPPLGGQQSQPSA
Sbjct: 1   MLLILLSVALLAFSSAQDLDEDVSQEDVPLVISDGGDSEQFIDEERQGPPLGGQQSQPSA 60

Query: 61  GDGNQDDGPQQGPPQQGGQQQQGPPPPQGKPQGPPQQGGHPPPPQGRPQGPPQQGGHPRP 120
           GDGNQ+DGPQQGPPQQGGQQQQGPPPPQGKPQGPPQQGGHPPPPQGRPQGPPQQGGHPRP
Sbjct: 61  GDGNQNDGPQQGPPQQGGQQQQGPPPPQGKPQGPPQQGGHPPPPQGRPQGPPQQGGHPRP 120

Query: 121 PRGRPQGPPQQGGHQQGPPPPPPGKPQGPPPQGGRPQGPPQGQSPQ 166
           PRGRPQGPPQQGGHQQGPPPPPPGKPQGPPPQGGRPQGPPQGQSPQ
Sbjct: 121 PRGRPQGPPQQGGHQQGPPPPPPGKPQGPPPQGGRPQGPPQGQSPQ 166


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score =  195 bits (495), Expect = 2e-50
 Identities = 108/200 (54%), Positives = 122/200 (61%), Gaps = 34/200 (17%)

Query: 1   MLLILLSVALLAFSSAQDLNEDVSQEDVPLVISDG--GDSEQFLDEERQGPPLGGQQSQP 58
           MLLILLSVALLA SSAQ+LNEDVSQE+ P +I+    G S Q  ++ +  PP  G+   P
Sbjct: 1   MLLILLSVALLALSSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGP 60

Query: 59  SAGDGNQDDGPQ-------------------------QGPPQQGGQQQQGPPPPQGKPQG 93
               GN+  GP                          QGPP QGG Q QGPPPP GKPQG
Sbjct: 61  PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQG 120

Query: 94  PPQQGGHPP---PPQGRPQGPPQQGGH---PRPPRGRPQGPPQQGGHQQGPPPPPPGKPQ 147
           PP QGG+ P   PP G+PQGPP QG     PR P G+PQGPP QGG+Q   PPPPPGKPQ
Sbjct: 121 PPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 180

Query: 148 GPPPQGG-RPQGPPQGQSPQ 166
           GPPPQGG +PQGPP    PQ
Sbjct: 181 GPPPQGGKKPQGPPPPGKPQ 200



 Score =  158 bits (400), Expect = 2e-39
 Identities = 80/132 (60%), Positives = 87/132 (65%), Gaps = 12/132 (9%)

Query: 47  QGPPLGGQ-QSQPSAGDGNQDD----GPQQGPPQQGGQQQQGPPPPQGKPQGPPQQGGHP 101
           QGPP  G+ Q  P  GD ++      G  QGPP QGG Q QGPPPP GKPQGPP QGG  
Sbjct: 130 QGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKK 189

Query: 102 P---PPQGRPQGPPQQGGHPRP---PRGRPQGPPQQGGHQQGPPPPPPGKPQGPPPQGG- 154
           P   PP G+PQGPP QG   R    P G+PQGPP QGG+Q   PPPPPGKPQGPPPQGG 
Sbjct: 190 PQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN 249

Query: 155 RPQGPPQGQSPQ 166
           +PQGPP    PQ
Sbjct: 250 KPQGPPPPGKPQ 261



 Score =  145 bits (367), Expect = 1e-35
 Identities = 79/141 (56%), Positives = 87/141 (61%), Gaps = 26/141 (18%)

Query: 47  QGPPLGGQ-QSQPSAGDGNQDD----GPQQGPPQQGGQQQQGPPPPQGKPQGPPQQGGHP 101
           QGPP  G+ Q  P  GD ++      G  QGPP QGG Q QGPPPP GKPQGPP QGG+ 
Sbjct: 191 QGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK 250

Query: 102 P---PPQGRPQGPPQQGG----HPRPPRGRPQGPPQQ-GGHQQGPPP-----------PP 142
           P   PP G+PQGPP QGG      R P G+PQGPPQQ G + QGPPP           PP
Sbjct: 251 PQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPP 310

Query: 143 PGKPQGP--PPQGGRPQGPPQ 161
            G+PQGP  PPQGGRP  PPQ
Sbjct: 311 AGQPQGPPRPPQGGRPSRPPQ 331


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score =  194 bits (492), Expect = 4e-50
 Identities = 103/173 (59%), Positives = 113/173 (65%), Gaps = 20/173 (11%)

Query: 1   MLLILLSVALLAFSSAQDLNEDVSQEDVPLVISDGGDSEQFLDEERQGPPLGGQQSQPSA 60
           MLLILLSVALLA SSAQ+LNEDVSQE+ P +I+               PP GG + Q   
Sbjct: 1   MLLILLSVALLALSSAQNLNEDVSQEESPSLIAGNPQG---------APPQGGNKPQGPP 51

Query: 61  GDGNQDDGPQQGPPQQGGQQQQGPPPPQGKPQGPPQQGGHPP---PPQGRPQGPPQQGGH 117
                  G  QGPP QGG Q QGPPPP GKPQGPP QGG+ P   PP G+PQGPP QG  
Sbjct: 52  SP----PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDK 107

Query: 118 ---PRPPRGRPQGPPQQGGHQQGPPPPPPGKPQGPPPQGG-RPQGPPQGQSPQ 166
              PR P G+PQGPP QGG+Q   PPPPPGKPQGPPPQGG +PQGPP    PQ
Sbjct: 108 SRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQ 160



 Score =  161 bits (408), Expect = 2e-40
 Identities = 81/134 (60%), Positives = 87/134 (64%), Gaps = 14/134 (10%)

Query: 47  QGPPLGGQ-QSQPSAGDGNQDD-----GPQQGPPQQGGQQQQGPPPPQGKPQGPPQQGGH 100
           QGPP  G+ Q  P  GD          G  QGPP QGG Q QGPPPP GKPQGPP QGG+
Sbjct: 213 QGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN 272

Query: 101 PP---PPQGRPQGPPQQGGHP----RPPRGRPQGPPQQGGHQQGPPPPPPGKPQGPPPQG 153
            P   PP G+PQGPP QGG      R P G+PQGPP QGG+Q   PPPPPGKPQGPPPQG
Sbjct: 273 KPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG 332

Query: 154 G-RPQGPPQGQSPQ 166
           G +PQGPP    PQ
Sbjct: 333 GNKPQGPPPPGKPQ 346



 Score =  159 bits (401), Expect = 1e-39
 Identities = 80/134 (59%), Positives = 87/134 (64%), Gaps = 14/134 (10%)

Query: 47  QGPPLGGQ-QSQPSAGDGNQDD-----GPQQGPPQQGGQQQQGPPPPQGKPQGPPQQGGH 100
           QGPP  G+ Q  P  GD          G  QGPP QGG Q QGPPPP GKPQGPP QGG+
Sbjct: 151 QGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN 210

Query: 101 PP---PPQGRPQGPPQQGGHP----RPPRGRPQGPPQQGGHQQGPPPPPPGKPQGPPPQG 153
            P   PP G+PQGPP QG +     R P G+PQGPP QGG+Q   PPPPPGKPQGPPPQG
Sbjct: 211 KPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG 270

Query: 154 G-RPQGPPQGQSPQ 166
           G +PQGPP    PQ
Sbjct: 271 GNKPQGPPPPGKPQ 284



 Score =  144 bits (362), Expect = 5e-35
 Identities = 76/134 (56%), Positives = 83/134 (61%), Gaps = 25/134 (18%)

Query: 49  PPLGGQQSQPSAGDGNQDDGPQQGPPQQGGQQQQGPPPPQGKPQGPPQQGGHPP---PPQ 105
           PP GG +S+ S        G  QGPP QGG Q QGPPPP GKPQGPP QGG+ P   PP 
Sbjct: 287 PPQGGSKSRSS----RSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPP 342

Query: 106 GRPQGPPQQGG----HPRPPRGRPQGPPQQ-GGHQQGPPP-----------PPPGKPQGP 149
           G+PQGPP QGG      R P G+PQGPPQQ G + QGPPP           PP G+PQGP
Sbjct: 343 GKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGP 402

Query: 150 --PPQGGRPQGPPQ 161
             PPQGGRP  PPQ
Sbjct: 403 PRPPQGGRPSRPPQ 416



 Score =  137 bits (346), Expect = 3e-33
 Identities = 78/149 (52%), Positives = 89/149 (59%), Gaps = 29/149 (19%)

Query: 44  EERQGPPLGGQQSQPSAGDGNQDDGPQ----QGPPQQGGQQQQGPPPPQGKPQGPPQQGG 99
           +  + PP   Q   P  G+  Q   P     QGPP QGG + QGPPPP GKPQGPP QGG
Sbjct: 233 QSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPP-GKPQGPPPQGG 291

Query: 100 HPP----PPQGRPQGPPQQGGH----PRPPRGRPQGPPQQGGHQ-QGPPPPPPGKPQGPP 150
                   P G+PQGPP QGG+    P PP G+PQGPP QGG++ QG  PPPPGKPQGPP
Sbjct: 292 SKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQG--PPPPGKPQGPP 349

Query: 151 PQG-----------GRPQGPPQ--GQSPQ 166
           PQG           G+PQGPPQ  G +PQ
Sbjct: 350 PQGGSKSRSARSPPGKPQGPPQQEGNNPQ 378


>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
           sapiens]
          Length = 309

 Score =  184 bits (466), Expect = 4e-47
 Identities = 103/190 (54%), Positives = 121/190 (63%), Gaps = 25/190 (13%)

Query: 1   MLLILLSVALLAFSSAQDLNEDVSQEDVPLVIS---DGGDSEQFLDEERQGPPLGGQQSQ 57
           MLLILLSVALLA SSAQ LNEDVSQE+ P VIS   +G   +     +R  PP G  + +
Sbjct: 1   MLLILLSVALLALSSAQSLNEDVSQEESPSVISGKPEGRRPQGGNQPQRTPPPPGKPEGR 60

Query: 58  PSAGDGNQDDGPQ------QGPPQQGGQQQQGPPPPQGKPQGPPQQGGH----PPPPQGR 107
           P  G GNQ  GP       +GPP QGG Q QGPPP  GKP+G P QGG+    PPP  G+
Sbjct: 61  PPQG-GNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPPRPGK 119

Query: 108 PQGPPQQGGH----PRPPRGRPQGPPQQGGHQQGPPPPPPGKPQGPPPQGG-RPQGP--- 159
           P+GPP QGG+    P P  G+P+GPP QGG+Q   PPP PGKP+GPPPQGG + QGP   
Sbjct: 120 PEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPH 179

Query: 160 ---PQGQSPQ 166
              P+G  PQ
Sbjct: 180 PGKPEGPPPQ 189



 Score =  145 bits (367), Expect = 1e-35
 Identities = 75/144 (52%), Positives = 86/144 (59%), Gaps = 26/144 (18%)

Query: 49  PPLGGQQSQ-----------PSAGDGNQDDGPQ------QGPPQQGGQQQQGPPPPQGKP 91
           PP GG QSQ           P    GNQ  GP       +GPP QGG Q QGPPP  GKP
Sbjct: 124 PPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKP 183

Query: 92  QGPPQQGGH----PPPPQGRPQGPPQQGGH----PRPPRGRPQGPPQQGGHQQGPPPPPP 143
           +GPP QGG+    PPP  G+P+GPP QGG+    P P  G+P+GPP QGG++   PPP P
Sbjct: 184 EGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHP 243

Query: 144 GKPQGPPPQ-GGRPQGPPQGQSPQ 166
           GKPQGPPPQ G +PQ PP    PQ
Sbjct: 244 GKPQGPPPQEGNKPQRPPPPGRPQ 267



 Score =  144 bits (364), Expect = 3e-35
 Identities = 82/165 (49%), Positives = 89/165 (53%), Gaps = 47/165 (28%)

Query: 49  PPLGGQQSQ-----------PSAGDGNQDDGPQ------QGPPQQGGQQQQGPPPPQGKP 91
           PP GG QSQ           P    GNQ  GP       +GPP QGG Q QGPPP  GKP
Sbjct: 145 PPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKP 204

Query: 92  QGPPQQGGH----PPP----PQG-------RPQGPPQQGGHPR-------------PPRG 123
           +GPP QGG+    PPP    P+G       +PQGPP   G P+             PP G
Sbjct: 205 EGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPG 264

Query: 124 RPQGPPQQGGHQQGPPPPPPGKPQG--PPPQGGRPQGPPQGQSPQ 166
           RPQGPP  GG+ Q P PPP GKPQG  PPPQGGRP  PPQGQ PQ
Sbjct: 265 RPQGPPPPGGNPQQPLPPPAGKPQGPPPPPQGGRPHRPPQGQPPQ 309



 Score = 39.3 bits (90), Expect = 0.002
 Identities = 27/67 (40%), Positives = 32/67 (47%), Gaps = 10/67 (14%)

Query: 36  GDSEQFLDEERQGPPLGGQQSQPSAGDGNQDDGPQQGPPQQGGQQQQGPPPPQG-----K 90
           G   Q  ++ ++ PP G  Q  P  G GN    PQQ  P   G+ Q  PPPPQG      
Sbjct: 248 GPPPQEGNKPQRPPPPGRPQGPPPPG-GN----PQQPLPPPAGKPQGPPPPPQGGRPHRP 302

Query: 91  PQGPPQQ 97
           PQG P Q
Sbjct: 303 PQGQPPQ 309


>gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2
           preproprotein [Homo sapiens]
          Length = 198

 Score =  171 bits (434), Expect = 2e-43
 Identities = 103/198 (52%), Positives = 119/198 (60%), Gaps = 37/198 (18%)

Query: 1   MLLILLSVALLAFSSAQDLNEDVSQEDVPLVISDG--GDSEQFLDEERQGPPLGGQQSQP 58
           MLLILLSVALLA SSAQ+LNEDVSQE+ P +I+    G S Q  ++ +  PP  G+   P
Sbjct: 1   MLLILLSVALLALSSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGP 60

Query: 59  SAGDGNQDDGPQ-----QGPPQQGGQQQ---------QGPPPPQGKPQGPPQQGGHPP-- 102
               GN+  GP      QGPP QG + +         QGPPP  GKPQGPP QGG+ P  
Sbjct: 61  PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGKPQGPPPQGGNKPQG 120

Query: 103 -PPQGRPQGPPQQGGHP----RPPRGRPQGPPQQ-GGHQQGPPP-----------PPPGK 145
            PP G+PQGPP QGG      R P G+PQGPPQQ G + QGPPP           PP G+
Sbjct: 121 PPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQ 180

Query: 146 PQGP--PPQGGRPQGPPQ 161
           PQGP  PPQGGRP  PPQ
Sbjct: 181 PQGPPRPPQGGRPSRPPQ 198


>gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Homo
           sapiens]
          Length = 247

 Score =  169 bits (427), Expect = 1e-42
 Identities = 98/196 (50%), Positives = 116/196 (59%), Gaps = 31/196 (15%)

Query: 1   MLLILLSVALLAFSSAQDLNEDVSQEDVPLVIS---DGGDSEQFLDEERQGPPLGGQQSQ 57
           MLLILLSVALLA SSA+  +EDVSQE+   +IS   +G   +     +R  PP G  Q  
Sbjct: 1   MLLILLSVALLALSSAESSSEDVSQEESLFLISGKPEGRRPQGGNQPQRPPPPPGKPQGP 60

Query: 58  PSAGDGNQDDGPQ------QGPPQQGGQQQQGPPPPQGKPQGPPQQGGHP----PPPQGR 107
           P  G GNQ  GP       +G P QGG Q QGPPP  GKP+ PP QGG+     PPP G+
Sbjct: 61  PPQG-GNQSQGPPPPPGKPEGRPPQGGNQSQGPPPHPGKPERPPPQGGNQSQGTPPPPGK 119

Query: 108 PQGPPQQGGH----PRPPRGRPQGPPQQGGHQQGPPPPPPGKPQGPPPQ----------- 152
           P+ PP QGG+    P PP G+P+ PP QGG+Q   PPP PGKP+GPPPQ           
Sbjct: 120 PERPPPQGGNQSHRPPPPPGKPERPPPQGGNQSQGPPPHPGKPEGPPPQEGNKSRSARSP 179

Query: 153 GGRPQGPPQ--GQSPQ 166
            G+PQGPPQ  G  PQ
Sbjct: 180 PGKPQGPPQQEGNKPQ 195



 Score = 85.1 bits (209), Expect = 2e-17
 Identities = 52/106 (49%), Positives = 58/106 (54%), Gaps = 27/106 (25%)

Query: 49  PPLGGQQSQ-----------PSAGDGNQD------DGPQQGPPQQGGQQQQGPPPPQGKP 91
           PP GG QSQ           P   +GN+        G  QGPPQQ G + QGPPPP GKP
Sbjct: 145 PPQGGNQSQGPPPHPGKPEGPPPQEGNKSRSARSPPGKPQGPPQQEGNKPQGPPPP-GKP 203

Query: 92  QGPPQQGGHPP----PPQGRPQG---PPQQGGHPRPPRGRPQGPPQ 130
           QGPP  GG+P     PP G+PQG   PPQ G  PRP +G  Q PPQ
Sbjct: 204 QGPPPAGGNPQQPQAPPAGKPQGPPPPPQGGRPPRPAQG--QQPPQ 247


>gi|41349486 proline-rich protein BstNI subfamily 1 isoform 3
           preproprotein [Homo sapiens]
          Length = 178

 Score =  163 bits (412), Expect = 7e-41
 Identities = 102/198 (51%), Positives = 112/198 (56%), Gaps = 57/198 (28%)

Query: 1   MLLILLSVALLAFSSAQDLNEDVSQEDVPLVISDGGDSEQFLDEERQGPPLGGQQSQPSA 60
           MLLILLSVALLA SSAQ+LNEDVSQE+ P +I+              G P G     PS 
Sbjct: 1   MLLILLSVALLALSSAQNLNEDVSQEESPSLIA--------------GNPQG-----PSP 41

Query: 61  GDGNQDDGPQ------QGPPQQGGQQQQGPPPPQGKPQGPPQQGGH-------------P 101
             GN+  GP       QGPP QGG + QGPPPP GKPQGPP QG               P
Sbjct: 42  QGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPP-GKPQGPPPQGDKSRSPRSPPGKPQGP 100

Query: 102 PPPQGRPQGPPQQGG----HPRPPRGRPQGPPQQ-GGHQQGPPP-----------PPPGK 145
           PP  G+PQGPP QGG      R P G+PQGPPQQ G + QGPPP           PP G+
Sbjct: 101 PPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQ 160

Query: 146 PQGP--PPQGGRPQGPPQ 161
           PQGP  PPQGGRP  PPQ
Sbjct: 161 PQGPPRPPQGGRPSRPPQ 178


>gi|154448886 proline rich 4 (lacrimal) isoform 2 [Homo sapiens]
          Length = 134

 Score = 96.3 bits (238), Expect = 1e-20
 Identities = 50/98 (51%), Positives = 59/98 (60%)

Query: 1  MLLILLSVALLAFSSAQDLNEDVSQEDVPLVISDGGDSEQFLDEERQGPPLGGQQSQPSA 60
          MLL+LLSV LLA SSAQ  + DV+ ED    I D  DS Q  D+  Q PP  G   +P  
Sbjct: 1  MLLVLLSVVLLALSSAQSTDNDVNYEDFTFTIPDVEDSSQRPDQGPQRPPPEGLLPRPPG 60

Query: 61 GDGNQDDGPQQGPPQQGGQQQQGPPPPQGKPQGPPQQG 98
            GNQDDGPQQ PP+ GG  +  PPPP    Q PP++G
Sbjct: 61 DSGNQDDGPQQRPPKPGGHHRHPPPPPFQNQQRPPRRG 98


>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
           subunit [Homo sapiens]
          Length = 551

 Score = 79.7 bits (195), Expect = 1e-15
 Identities = 60/151 (39%), Positives = 67/151 (44%), Gaps = 26/151 (17%)

Query: 38  SEQFLDEERQGPPLGGQQSQ-PSAG-----------DGNQDDGPQQ--GPPQQGGQQQQG 83
           S Q   E + GPP G  ++  P  G            G++  GP    GPP      Q  
Sbjct: 177 SGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTP 236

Query: 84  PPPPQGKPQGPPQQGGHPPPPQGRPQ---GPPQQGGHPRPP---RGRPQGPPQQGGHQQG 137
           P PP G P GPP   G PPP Q  P    GPP +G  P PP    G+P G P  G    G
Sbjct: 237 PRPPLGPP-GPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPG 295

Query: 138 PPPPPPG---KPQGPPPQGGRPQGPPQGQSP 165
           PPPP PG    P  PPPQ G P  PP G  P
Sbjct: 296 PPPPVPGYGPPPGPPPPQQGPP--PPPGPFP 324



 Score = 62.4 bits (150), Expect = 2e-10
 Identities = 53/139 (38%), Positives = 55/139 (39%), Gaps = 29/139 (20%)

Query: 50  PLGGQQSQPSAGDGNQDDGPQQGPPQQGGQQQQGPPPP-QGKPQ---GPPQQGGHPPPP- 104
           P G     P    G     P  GPP   G    GPPPP Q  P    GPP +G  PPPP 
Sbjct: 220 PAGPGGPPPPFPAGQTPPRPPLGPPGPPGPP--GPPPPGQVLPPPLAGPPNRGDRPPPPV 277

Query: 105 --QGRPQGPPQQGGHPR----------PPRGRP---QGPPQQGGHQQGPPPPPPGKPQGP 149
              G+P G P  G  P           PP G P   QGPP       GP PP P  P GP
Sbjct: 278 LFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPP----PPGPFPPRPPGPLGP 333

Query: 150 PPQGGRP---QGPPQGQSP 165
           P     P    GPP G  P
Sbjct: 334 PLTLAPPPHLPGPPPGAPP 352



 Score = 61.6 bits (148), Expect = 3e-10
 Identities = 50/111 (45%), Positives = 51/111 (45%), Gaps = 16/111 (14%)

Query: 48  GPPLGGQQSQPS-AGDGNQDDGPQQG---PPQQGGQQQQGPPPPQGKPQGPPQQG-GHPP 102
           GPP  GQ   P  AG  N+ D P      P Q  GQ   GP PP G P  PP  G G PP
Sbjct: 251 GPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPP-GPP--PPVPGYGPPP 307

Query: 103 PPQGRPQGPPQQGG--HPRPPRGRPQGPPQQGGHQQGPPPPPPGKPQGPPP 151
            P    QGPP   G   PRPP   P GPP        PPP  PG P G PP
Sbjct: 308 GPPPPQQGPPPPPGPFPPRPP--GPLGPPL----TLAPPPHLPGPPPGAPP 352



 Score = 53.9 bits (128), Expect = 6e-08
 Identities = 48/145 (33%), Positives = 49/145 (33%), Gaps = 27/145 (18%)

Query: 40  QFLDEERQGPPLGGQQSQPSAGDGNQDDG--------PQQGPPQQGGQQQQGPPPPQGKP 91
           Q L     GPP  G +  P      Q  G        P   PP  G     GPPP     
Sbjct: 257 QVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPP---PQ 313

Query: 92  QGPPQQGGHPPPPQGRPQGPPQQGGHPRPPRGRPQGPPQQGGHQQG---PPP-------- 140
           QGPP   G  PP    P GPP     P    G P G P    H      PPP        
Sbjct: 314 QGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTS 373

Query: 141 ----PPPGKPQG-PPPQGGRPQGPP 160
               PPP  P G PPP      GPP
Sbjct: 374 DSRGPPPTDPYGRPPPYDRGDYGPP 398


>gi|7706501 WW domain binding protein 11 [Homo sapiens]
          Length = 641

 Score = 78.6 bits (192), Expect = 2e-15
 Identities = 61/154 (39%), Positives = 71/154 (46%), Gaps = 32/154 (20%)

Query: 34  DGGDSEQFL---DEERQGPPLGGQQSQPSAGDGNQDDGP------QQGPPQQGGQQQ-QG 83
           +G + E+F    DE+        +QSQ    + +  DG       QQ PPQ     Q Q 
Sbjct: 345 EGREVEEFSEDDDEDDSDDSEAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQA 404

Query: 84  PP----PPQGKPQGPPQQGGHPPPPQGRPQGPPQQGGHP--RPP----------RGRPQG 127
           PP    PP G P  PP +   P PP G P GPP  G  P  RPP          R  P G
Sbjct: 405 PPMPGPPPLGPPPAPPLRP--PGPPTGLPPGPPP-GAPPFLRPPGMPGLRGPLPRLLPPG 461

Query: 128 PPQQGGHQQGPPP-PPPGKPQGPPPQGGRPQGPP 160
           PP   G   GPPP PPPG P GPPP+G  P+ PP
Sbjct: 462 PPP--GRPPGPPPGPPPGLPPGPPPRGPPPRLPP 493



 Score = 73.9 bits (180), Expect = 6e-14
 Identities = 53/153 (34%), Positives = 59/153 (38%), Gaps = 38/153 (24%)

Query: 37  DSEQFLDEERQGPPLGGQQSQPSAGDGNQDDGPQQGPPQQG---GQQQQGPPPPQGKPQG 93
           D       ++Q PP     SQ  A        P  GPP  G       + P PP G P G
Sbjct: 381 DGTSTASSQQQAPPQSVPPSQIQAP-------PMPGPPPLGPPPAPPLRPPGPPTGLPPG 433

Query: 94  PPQQGGHPP---------------------PPQGRPQGPPQQGGHPRPPRGRPQGPPQQG 132
           PP   G PP                     PP GRP GPP     P PP G P GPP +G
Sbjct: 434 PPP--GAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPP-----PGPPPGLPPGPPPRG 486

Query: 133 GHQQGPPPPPPGKPQGPPPQGGRPQGPPQGQSP 165
              + PPP PPG P   P     P  PP G +P
Sbjct: 487 PPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAP 519



 Score = 61.2 bits (147), Expect = 4e-10
 Identities = 49/130 (37%), Positives = 55/130 (42%), Gaps = 33/130 (25%)

Query: 49  PPLGGQQSQPSAGDG---NQDDGPQQGPPQ----------QGGQQQQGPP-PPQGKPQGP 94
           PPLG   + P    G       GP  G P           +G   +  PP PP G+P GP
Sbjct: 411 PPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGP 470

Query: 95  PQQGGHPPPPQGRPQGPPQQGGHPRPPRGRPQGPPQQGGHQQGPPPPPPGKPQGP--PPQ 152
           P     P PP G P GPP +G  PR P   P  PP       G PPP PG  + P  PP 
Sbjct: 471 P-----PGPPPGLPPGPPPRGPPPRLP---PPAPP-------GIPPPRPGMMRPPLVPPL 515

Query: 153 GGRPQG--PP 160
           G  P G  PP
Sbjct: 516 GPAPPGLFPP 525



 Score = 55.8 bits (133), Expect = 2e-08
 Identities = 42/114 (36%), Positives = 49/114 (42%), Gaps = 5/114 (4%)

Query: 48  GPPLGGQQS-QPSAGDGNQDDGPQQGPPQQGGQQQQGPPP--PQGKPQGPPQQGGHPPPP 104
           GPP G     +P    G +   P+  PP     +  GPPP  P G P GPP +G  P  P
Sbjct: 433 GPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLP 492

Query: 105 QGRPQG-PPQQGGHPRPPRGRPQGPPQQGGHQQGPPPPPPGKPQGPPPQGGRPQ 157
              P G PP + G  RPP   P GP   G      P P PG    PP    RP+
Sbjct: 493 PPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPA-PLPNPGVLSAPPNLIQRPK 545



 Score = 28.1 bits (61), Expect = 3.6
 Identities = 21/48 (43%), Positives = 22/48 (45%), Gaps = 16/48 (33%)

Query: 127 GPPQQG-------GHQQGPPPPPPG-KPQGPPPQGGRPQGPPQGQSPQ 166
           GPP +        GH  G P  PPG KP GPPP      GPP  Q  Q
Sbjct: 174 GPPTRAVSILPLLGH--GVPRLPPGRKPPGPPP------GPPPPQVVQ 213



 Score = 27.3 bits (59), Expect = 6.1
 Identities = 23/65 (35%), Positives = 26/65 (40%), Gaps = 12/65 (18%)

Query: 92  QGPPQQGGHPPP--PQGRPQGPPQQGGHPRPPRGR--PQGPPQQGGHQQGPPPPPPGKPQ 147
           Q  P  G  PP    +    GPP +     P  G   P+ PP  G    GPPP P     
Sbjct: 154 QDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPP--GRKPPGPPPGP----- 206

Query: 148 GPPPQ 152
            PPPQ
Sbjct: 207 -PPPQ 210


>gi|19924099 synapsin I isoform Ia [Homo sapiens]
          Length = 705

 Score = 75.9 bits (185), Expect = 2e-14
 Identities = 59/152 (38%), Positives = 62/152 (40%), Gaps = 42/152 (27%)

Query: 50  PLGGQQSQPSAGD-GNQDDGPQQGPPQQG-GQQQQGPP-----PPQGK------------ 90
           PLG Q SQ  AG    Q   PQ GPPQ G G Q+QGPP     PPQG+            
Sbjct: 443 PLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGS 502

Query: 91  ------------PQGPPQQGGHPPPPQGRPQGPPQQGGHPRPPRGRPQGPPQQGGHQQGP 138
                       PQ P  Q   P   QGR Q  P  GG   PP  RP   P     Q GP
Sbjct: 503 PLPQRLPSPTSAPQQPASQAAPPTQGQGR-QSRPVAGGPGAPPAARPPASPSPQ-RQAGP 560

Query: 139 PP---------PPPGKPQGPPPQGGRPQGPPQ 161
           P          P P K  G PP G + QGPPQ
Sbjct: 561 PQATRQTSVSGPAPPKASGAPPGGQQRQGPPQ 592



 Score = 55.8 bits (133), Expect = 2e-08
 Identities = 51/169 (30%), Positives = 64/169 (37%), Gaps = 27/169 (15%)

Query: 15  SAQDLNEDVSQEDVPLVISDGGDSEQFLDEERQGPPLGGQQSQPSAGDGNQDDGPQQGPP 74
           S+  L  D   ED  L++      E  +++  Q  P   +Q   S G G+    P  G  
Sbjct: 390 SSMPLIGDHQDEDKQLIV------ELVVNKMAQALPRQ-RQRDASPGRGSHGQTPSPGAL 442

Query: 75  QQGGQQQQGPPPPQGKPQGPPQQGGHPPPPQGRPQGPPQQ-----------------GGH 117
             G Q  Q P  P  + + PPQ G   P P  + QGPP Q                  G 
Sbjct: 443 PLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGS 502

Query: 118 PRPPR-GRPQGPPQQGGHQQGPPPPPPGKPQGPPPQGGRPQGPPQGQSP 165
           P P R   P   PQQ   Q  PP    G+ Q  P  GG P  PP  + P
Sbjct: 503 PLPQRLPSPTSAPQQPASQAAPPTQGQGR-QSRPVAGG-PGAPPAARPP 549



 Score = 47.8 bits (112), Expect = 4e-06
 Identities = 44/138 (31%), Positives = 51/138 (36%), Gaps = 30/138 (21%)

Query: 46  RQGPPLGGQQSQPSAGDGNQDDGPQQ--GPPQQ-------------------GGQQQQGP 84
           RQ  P+ G    P A        PQ+  GPPQ                    GGQQ+QGP
Sbjct: 531 RQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGP 590

Query: 85  -PPPQGKPQGPPQQGGHPPPPQGRPQGPPQQGGHPRP----PRGRPQGPPQQGGHQQGPP 139
              P G P GP +Q     P    P+  P     PRP    P GRP+    Q   Q  PP
Sbjct: 591 PQKPPG-PAGPTRQASQAGPV---PRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPP 646

Query: 140 PPPPGKPQGPPPQGGRPQ 157
           P        P PQ  + Q
Sbjct: 647 PATAAAGGPPHPQLNKSQ 664


>gi|19924097 synapsin I isoform Ib [Homo sapiens]
          Length = 669

 Score = 75.9 bits (185), Expect = 2e-14
 Identities = 59/152 (38%), Positives = 62/152 (40%), Gaps = 42/152 (27%)

Query: 50  PLGGQQSQPSAGD-GNQDDGPQQGPPQQG-GQQQQGPP-----PPQGK------------ 90
           PLG Q SQ  AG    Q   PQ GPPQ G G Q+QGPP     PPQG+            
Sbjct: 443 PLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGS 502

Query: 91  ------------PQGPPQQGGHPPPPQGRPQGPPQQGGHPRPPRGRPQGPPQQGGHQQGP 138
                       PQ P  Q   P   QGR Q  P  GG   PP  RP   P     Q GP
Sbjct: 503 PLPQRLPSPTSAPQQPASQAAPPTQGQGR-QSRPVAGGPGAPPAARPPASPSPQ-RQAGP 560

Query: 139 PP---------PPPGKPQGPPPQGGRPQGPPQ 161
           P          P P K  G PP G + QGPPQ
Sbjct: 561 PQATRQTSVSGPAPPKASGAPPGGQQRQGPPQ 592



 Score = 55.8 bits (133), Expect = 2e-08
 Identities = 51/169 (30%), Positives = 64/169 (37%), Gaps = 27/169 (15%)

Query: 15  SAQDLNEDVSQEDVPLVISDGGDSEQFLDEERQGPPLGGQQSQPSAGDGNQDDGPQQGPP 74
           S+  L  D   ED  L++      E  +++  Q  P   +Q   S G G+    P  G  
Sbjct: 390 SSMPLIGDHQDEDKQLIV------ELVVNKMAQALPRQ-RQRDASPGRGSHGQTPSPGAL 442

Query: 75  QQGGQQQQGPPPPQGKPQGPPQQGGHPPPPQGRPQGPPQQ-----------------GGH 117
             G Q  Q P  P  + + PPQ G   P P  + QGPP Q                  G 
Sbjct: 443 PLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGS 502

Query: 118 PRPPR-GRPQGPPQQGGHQQGPPPPPPGKPQGPPPQGGRPQGPPQGQSP 165
           P P R   P   PQQ   Q  PP    G+ Q  P  GG P  PP  + P
Sbjct: 503 PLPQRLPSPTSAPQQPASQAAPPTQGQGR-QSRPVAGG-PGAPPAARPP 549



 Score = 49.3 bits (116), Expect = 2e-06
 Identities = 46/144 (31%), Positives = 52/144 (36%), Gaps = 32/144 (22%)

Query: 46  RQGPPLGGQQSQPSAGDGNQDDGPQQ--GPPQQ-------------------GGQQQQGP 84
           RQ  P+ G    P A        PQ+  GPPQ                    GGQQ+QGP
Sbjct: 531 RQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGP 590

Query: 85  -PPPQGKPQGPPQQGGHPPPPQGRPQGPPQQGGHPRP----PRGRPQGPPQQGGHQQGPP 139
              P G P GP +Q     P    P+  P     PRP    P GRP+  PQ         
Sbjct: 591 PQKPPG-PAGPTRQASQAGPV---PRTGPPTTQQPRPSGPGPAGRPK--PQLAQKPSQDV 644

Query: 140 PPPPGKPQGPPPQGGRPQGPPQGQ 163
           PPP     G PP       P Q Q
Sbjct: 645 PPPATAAAGGPPHPQLKASPAQAQ 668



 Score = 29.6 bits (65), Expect = 1.2
 Identities = 23/65 (35%), Positives = 26/65 (40%), Gaps = 9/65 (13%)

Query: 46  RQGPPLGGQQSQPSAGDGNQDDGPQQGPPQQGGQQ--QQGPPPPQGKPQGPPQQGGHPPP 103
           R GPP   QQ +PS        GP   P  Q  Q+  Q  PPP      GPP       P
Sbjct: 612 RTGPPTT-QQPRPSG------PGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLKASP 664

Query: 104 PQGRP 108
            Q +P
Sbjct: 665 AQAQP 669


>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
            sapiens]
          Length = 1362

 Score = 73.6 bits (179), Expect = 7e-14
 Identities = 54/134 (40%), Positives = 60/134 (44%), Gaps = 30/134 (22%)

Query: 43   DEERQGPPLGGQQSQ----------------PSAGDGNQDDGPQQGPPQQGGQQQ---QG 83
            DEE   PPL   Q Q                PS    +Q   P   PP    QQQ   Q 
Sbjct: 915  DEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQP 974

Query: 84   PPPPQGKPQGPPQQGGHPPPPQGRPQGPPQQGGHPRPPRGRPQGPPQQGGHQQGPPPPPP 143
            PPPP  +PQ PPQQ  H PPP+     P Q   H + P      PP QG   Q PP PPP
Sbjct: 975  PPPPPPQPQPPPQQQ-HQPPPRPVHLQPMQFSTHIQQP------PPPQG---QQPPHPPP 1024

Query: 144  GKPQGPPPQGGRPQ 157
            G+ Q PPPQ  +PQ
Sbjct: 1025 GQ-QPPPPQPAKPQ 1037



 Score = 53.9 bits (128), Expect = 6e-08
 Identities = 43/120 (35%), Positives = 48/120 (40%), Gaps = 7/120 (5%)

Query: 45   ERQGPPLGGQQSQPSAGDGNQDDG-PQQGPPQQGGQQQQGPPPPQGKPQGPPQ--QGGHP 101
            ++Q PP    Q QP     +Q    P    P Q     Q PPPPQG  Q PP    G  P
Sbjct: 971  QQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQG--QQPPHPPPGQQP 1028

Query: 102  PPPQGRPQGPPQQGGHPRPPRGRPQGPPQQGGHQQGPPPPPPGKPQGPPPQGGRPQGPPQ 161
            PPPQ  P  P Q   H   PR     P   G  ++ P P     PQ    Q    Q PPQ
Sbjct: 1029 PPPQ--PAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQ 1086



 Score = 48.9 bits (115), Expect = 2e-06
 Identities = 36/109 (33%), Positives = 42/109 (38%), Gaps = 18/109 (16%)

Query: 33  SDGGDSEQFLDEERQGPPLGGQQSQPSAGDGNQDDGPQQGPPQQGGQQQQGPPPPQGKPQ 92
           S   DSE   D E +  P   ++  P            Q       Q QQ P P   +P 
Sbjct: 709 SSSSDSE---DSETEMAPKSKKKGHPGREQKKHHHHHHQ-------QMQQAPAPVPQQPP 758

Query: 93  GPPQQGGHPPPPQGRPQGPPQQGGHPRPPRGRPQGPPQQGGHQQGPPPP 141
            PPQQ   PPPPQ + Q PP     P PP   P  P Q     +  PPP
Sbjct: 759 PPPQQPPPPPPPQQQQQPPP-----PPPP---PSMPQQAAPAMKSSPPP 799



 Score = 40.0 bits (92), Expect = 0.001
 Identities = 27/73 (36%), Positives = 30/73 (41%), Gaps = 16/73 (21%)

Query: 99  GHPPPPQGRPQGPPQQGGH------PRPPRGRPQGPPQQGGHQQGPPPPPPGKPQGPPPQ 152
           GHP    GR Q       H      P P   +P  PPQQ      PPPPPP + Q  PP 
Sbjct: 729 GHP----GREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQ------PPPPPPPQQQQQPPP 778

Query: 153 GGRPQGPPQGQSP 165
              P   PQ  +P
Sbjct: 779 PPPPPSMPQQAAP 791



 Score = 33.5 bits (75), Expect = 0.086
 Identities = 29/97 (29%), Positives = 32/97 (32%), Gaps = 3/97 (3%)

Query: 70   QQGPPQQGGQQQQGPP---PPQGKPQGPPQQGGHPPPPQGRPQGPPQQGGHPRPPRGRPQ 126
            QQ PP QG Q    PP   PP  +P  P Q   H   P+     P   G     P     
Sbjct: 1009 QQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMI 1068

Query: 127  GPPQQGGHQQGPPPPPPGKPQGPPPQGGRPQGPPQGQ 163
              PQ    Q      PP +   P  Q  R     Q Q
Sbjct: 1069 HSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQ 1105



 Score = 32.7 bits (73), Expect = 0.15
 Identities = 35/138 (25%), Positives = 44/138 (31%), Gaps = 44/138 (31%)

Query: 70  QQGPPQQGGQQQQGPPPPQGKPQG------------------PPQQGGHPPPPQGRPQGP 111
           Q   P Q    Q  PPP Q  P                    PPQ    PPP   +PQ P
Sbjct: 201 QASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPP 260

Query: 112 PQQGGHPRPPRGRP---QGPPQQGGHQQG-----------------PPPPPPGKPQ---- 147
           P     P+P +  P      PQ    ++G                  PP  P +P+    
Sbjct: 261 PAPA--PQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKL 318

Query: 148 GPPPQGGRPQGPPQGQSP 165
           G   +  RP  PP+   P
Sbjct: 319 GQRRESSRPVKPPKKDVP 336



 Score = 32.7 bits (73), Expect = 0.15
 Identities = 20/51 (39%), Positives = 20/51 (39%), Gaps = 4/51 (7%)

Query: 116 GHPRPPRGRPQGPPQQGGHQQGPPPPPPGKPQGPPPQGGRPQGPPQGQSPQ 166
           GHP    GR Q       HQQ    P P   Q PPP    P  PP  Q  Q
Sbjct: 729 GHP----GREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQ 775



 Score = 32.0 bits (71), Expect = 0.25
 Identities = 20/65 (30%), Positives = 25/65 (38%), Gaps = 2/65 (3%)

Query: 104 PQGRPQGPP--QQGGHPRPPRGRPQGPPQQGGHQQGPPPPPPGKPQGPPPQGGRPQGPPQ 161
           P+ + +G P  +Q  H      + Q  P     Q  PPP  P  P  P  Q   P  PP 
Sbjct: 723 PKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPP 782

Query: 162 GQSPQ 166
              PQ
Sbjct: 783 PSMPQ 787



 Score = 30.4 bits (67), Expect = 0.73
 Identities = 43/186 (23%), Positives = 49/186 (26%), Gaps = 89/186 (47%)

Query: 69   PQQGPPQQGGQQQQGPPPP--QGKPQGPPQQGGH----PPPPQGRPQGPP---QQGGHPR 119
            P+   P    Q     PP      PQ P +        PP P   P   P   Q    P+
Sbjct: 843  PEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQ 902

Query: 120  PPRGRP--------------------------------------------QGPPQ----- 130
            PP  +P                                            Q PP      
Sbjct: 903  PPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPP 962

Query: 131  ----QGGHQQGPPPPPPGKP---------------------------QGPPPQGGRPQGP 159
                Q   QQ PPPPPP +P                           Q PPPQG +P  P
Sbjct: 963  HPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHP 1022

Query: 160  PQGQSP 165
            P GQ P
Sbjct: 1023 PPGQQP 1028



 Score = 30.0 bits (66), Expect = 0.95
 Identities = 43/190 (22%), Positives = 53/190 (27%), Gaps = 64/190 (33%)

Query: 40   QFLDEERQGPPLGGQQSQPSAGDGNQDDGPQQGPPQQGGQQQQGPPPPQGKP-------- 91
            QF    +Q PP  GQQ  P    G Q   PQ   PQQ  Q    P   +  P        
Sbjct: 1003 QFSTHIQQPPPPQGQQP-PHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLRE 1061

Query: 92   --------------------QGPPQQGGHP------------PPP--------------Q 105
                                Q PPQQ   P            P P              +
Sbjct: 1062 APSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIR 1121

Query: 106  GRPQGPPQQGGHPRPPRG---------RPQGPPQQGGHQQGPPPPPPGKPQGPPPQGGRP 156
              P  P  +   P+ P           RP+  P   G     PP     P G P +  + 
Sbjct: 1122 SEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQK 1181

Query: 157  QGPPQGQSPQ 166
            Q P    +P+
Sbjct: 1182 QEPKTPVAPK 1191


>gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]
          Length = 1336

 Score = 73.6 bits (179), Expect = 7e-14
 Identities = 57/158 (36%), Positives = 65/158 (41%), Gaps = 43/158 (27%)

Query: 44  EERQGP-PLGGQQSQ-PSAGDGNQDDGPQQGPPQQGG-----QQQQGPPPPQGKPQGPPQ 96
           +E +GP P GG     P    G Q+    QGPP QG      Q+ +GPP  Q + QGPPQ
Sbjct: 808 QEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQ-QGPPQ 866

Query: 97  QGGHPPPPQGRPQGPPQQGGHPRPPRG--------------------RPQGPPQQGGHQQ 136
            G   PPPQG  QGPP   G   P RG                     P+ P  Q G   
Sbjct: 867 -GSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQST 925

Query: 137 GPPP--------------PPPGKPQGPPPQGGRPQGPP 160
           GPPP              PP    QGP P  G  +GPP
Sbjct: 926 GPPPLIPGLGQQGAQGRIPPLNPGQGPGPNKGDSRGPP 963



 Score = 73.2 bits (178), Expect = 1e-13
 Identities = 58/145 (40%), Positives = 65/145 (44%), Gaps = 20/145 (13%)

Query: 39  EQFLDEERQGPPLGGQQSQPSAGDGNQ-DDGPQQGPPQQG---GQQQQGPPPPQG--KPQ 92
           EQ       G PL G Q  P  G  +Q   G QQ  P Q       Q GPP PQG  +P 
Sbjct: 570 EQIQPPPSSGTPLLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPP 629

Query: 93  GPPQQGGHPPPPQGRPQGPPQQGGHPRPPRGRPQGPPQ------QGGHQQGPPPPPPGKP 146
           GP  Q G   PP  +  G PQ    P+ P+G PQG P+        G Q+ P P  P  P
Sbjct: 630 GPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGP 689

Query: 147 QGPP-PQGGR-------PQGPPQGQ 163
           QGPP PQG         PQGPP  Q
Sbjct: 690 QGPPGPQGSSGPQGHMGPQGPPGPQ 714



 Score = 71.6 bits (174), Expect = 3e-13
 Identities = 61/147 (41%), Positives = 66/147 (44%), Gaps = 29/147 (19%)

Query: 47  QGPPLGGQQSQPSAGDGNQD-DGPQQGPPQ-------QGGQQQQGPPPPQGKPQGPP-QQ 97
           QGPPL      P    G Q   GP QG P+       QG Q+  GP  P G PQGPP  Q
Sbjct: 638 QGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLG-PQGPPGPQ 696

Query: 98  GGHPPPPQGRPQGPPQQGGH-----PRPPRGR--PQGPPQQGGHQQGPP-------PPPP 143
           G   P     PQGPP   GH     P  P+G   PQGPP   G  QGPP       PP P
Sbjct: 697 GSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQG-MQGPPGPRGMQGPPHP 755

Query: 144 GKPQGPPP----QGGRPQGPPQGQSPQ 166
              QG P     QG   QGP  G +P+
Sbjct: 756 HGIQGGPGSQGIQGPVSQGPLMGLNPR 782



 Score = 68.2 bits (165), Expect = 3e-12
 Identities = 60/143 (41%), Positives = 65/143 (45%), Gaps = 28/143 (19%)

Query: 47  QGPP-----LGGQQSQPSAGDGNQDDGPQQGPPQQGGQQQQGP-----PPPQGKPQG-PP 95
           QGPP      GG  SQ   G  +Q  GP  G   +G Q   GP     P PQG   G PP
Sbjct: 750 QGPPHPHGIQGGPGSQGIQGPVSQ--GPLMGLNPRGMQGPPGPRENQGPAPQGMIMGHPP 807

Query: 96  QQGGHPPPPQGRPQGPPQQGGHPRPPRGRPQGPPQQGGHQQGPP-----PP-------PP 143
           Q+   P PP G     PQ+   P+  RG  QGPP QG    GPP     PP       PP
Sbjct: 808 QEMRGPHPPGGLLGHGPQEMRGPQEIRGM-QGPPPQGS-MLGPPQELRGPPGSQSQQGPP 865

Query: 144 GKPQGPPPQGGRPQGPPQGQSPQ 166
               GPPPQGG  QGPP  Q  Q
Sbjct: 866 QGSLGPPPQGG-MQGPPGPQGQQ 887



 Score = 64.3 bits (155), Expect = 5e-11
 Identities = 59/160 (36%), Positives = 61/160 (38%), Gaps = 45/160 (28%)

Query: 47  QGPPLGGQQSQPSAGDGNQDDGPQQGPPQQGGQQ-------QQGPPPPQGKPQGPPQQGG 99
           QGPP       P    G Q     QGPP   G Q        QGPP P G   GP  QG 
Sbjct: 708 QGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGI 767

Query: 100 HPPPPQGRPQGPPQQGGHPRPPRGRP-----QGPPQQGGHQQGPP-----PPPPG----- 144
             P  QG     P  G +PR  +G P     QGP  QG     PP     P PPG     
Sbjct: 768 QGPVSQG-----PLMGLNPRGMQGPPGPRENQGPAPQGMIMGHPPQEMRGPHPPGGLLGH 822

Query: 145 ------------KPQGPPPQG---GRPQ---GPPQGQSPQ 166
                         QGPPPQG   G PQ   GPP  QS Q
Sbjct: 823 GPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQ 862



 Score = 63.5 bits (153), Expect = 8e-11
 Identities = 55/132 (41%), Positives = 57/132 (43%), Gaps = 23/132 (17%)

Query: 54  QQSQPSAGDGNQDDGPQ----QGPPQQGGQQQQGPPPPQGKPQGPPQQGGHPPPPQG--R 107
           +Q QP    G    GPQ    QGP  Q  Q  Q P P Q  P    Q G  PP PQG  R
Sbjct: 570 EQIQPPPSSGTPLLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMG--PPGPQGQFR 627

Query: 108 PQGPPQQGGHPRPPRGRPQGPPQQGGHQQGPPPPPPG--------KPQG----PPPQGG- 154
           P GP  Q G   PP  +  G PQ     QGP  PP G         PQG    P P G  
Sbjct: 628 PPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPL 687

Query: 155 RPQGP--PQGQS 164
            PQGP  PQG S
Sbjct: 688 GPQGPPGPQGSS 699



 Score = 63.2 bits (152), Expect = 1e-10
 Identities = 56/146 (38%), Positives = 65/146 (44%), Gaps = 14/146 (9%)

Query: 29  PLVISDGGDSEQFLDEERQGPPLG----GQQSQPSAGDGNQDDGPQQGPPQQGGQQQQGP 84
           P  I  G  S+       QGP +G    G Q  P   + NQ   PQ        Q+ +GP
Sbjct: 755 PHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPRE-NQGPAPQGMIMGHPPQEMRGP 813

Query: 85  PPPQGKPQGPPQQGGHPPPPQGRPQGPPQQG---GHPRPPRGRPQGPPQQGGHQQGP-PP 140
            PP G     PQ+   P   +G  QGPP QG   G P+  RG P G   Q G  QG   P
Sbjct: 814 HPPGGLLGHGPQEMRGPQEIRGM-QGPPPQGSMLGPPQELRG-PPGSQSQQGPPQGSLGP 871

Query: 141 PPPGKPQGPP-PQGGRPQGPPQGQSP 165
           PP G  QGPP PQG   Q P +G  P
Sbjct: 872 PPQGGMQGPPGPQG--QQNPARGPHP 895



 Score = 61.6 bits (148), Expect = 3e-10
 Identities = 55/134 (41%), Positives = 58/134 (43%), Gaps = 24/134 (17%)

Query: 46  RQGPPLGGQQSQPSAGDGNQDDGPQQGPPQQGGQQQQG---PPPPQGK------------ 90
           + GPP    Q +P    G    GPQ  P  QGG   QG   P  PQG             
Sbjct: 616 QMGPPGPQGQFRPPGPQGQM--GPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHG 673

Query: 91  PQGPPQQGGHPPPPQGRPQGPPQQGGHPRPP-RGRPQGPPQQGGH--QQGPPPPPPG-KP 146
           PQG  +  G P  P G PQGPP   G   P     PQGPP   GH   QGPP P     P
Sbjct: 674 PQGMQRHPG-PHGPLG-PQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGP 731

Query: 147 QGPPPQGGRPQGPP 160
           QGPP   G  QGPP
Sbjct: 732 QGPPGTQGM-QGPP 744



 Score = 53.5 bits (127), Expect = 8e-08
 Identities = 50/152 (32%), Positives = 62/152 (40%), Gaps = 24/152 (15%)

Query: 35   GGDSEQFLDEERQGPPLGGQQSQPSAGDGNQDDGPQQGP-PQQGG---QQQQ------GP 84
            G  S+Q   +   GPP  G    P    G Q+  P +GP P QG    QQQ+      GP
Sbjct: 857  GSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQN--PARGPHPSQGPIPFQQQKTPLLGDGP 914

Query: 85   PPP---QGKPQGPP-------QQGGHPP-PPQGRPQGPPQQGGHPRPPRGRPQGPPQQGG 133
              P   +G+  GPP       QQG     PP    QGP    G  R P     GP  +  
Sbjct: 915  RAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPGQGPGPNKGDSRGPPNHHMGPMSERR 974

Query: 134  HQQGPPPPPPGKPQGPPPQGGRPQGPPQGQSP 165
            H+Q    P  G  +GP   G   +GPP  + P
Sbjct: 975  HEQS-GGPEHGPERGPFRGGQDCRGPPDRRGP 1005



 Score = 47.4 bits (111), Expect = 6e-06
 Identities = 37/114 (32%), Positives = 44/114 (38%), Gaps = 11/114 (9%)

Query: 47   QGPPLGGQQSQPSAGDGNQ----DDGPQQGPPQQ----GGQQQQGPPPPQGKPQGPPQQG 98
            QGP    QQ  P  GDG +     +G   GPP      G Q  QG  PP    QGP    
Sbjct: 897  QGPIPFQQQKTPLLGDGPRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPGQGPGPNK 956

Query: 99   GHPPPPQGRPQGPPQQGGHPR---PPRGRPQGPPQQGGHQQGPPPPPPGKPQGP 149
            G    P     GP  +  H +   P  G  +GP + G   +GPP      P  P
Sbjct: 957  GDSRGPPNHHMGPMSERRHEQSGGPEHGPERGPFRGGQDCRGPPDRRGPHPDFP 1010



 Score = 42.4 bits (98), Expect = 2e-04
 Identities = 42/137 (30%), Positives = 60/137 (43%), Gaps = 28/137 (20%)

Query: 45   ERQGPP---LGGQQSQPSAGDGNQDDGPQQGPPQQGGQQQQGPPPPQGKPQGPPQQGGHP 101
            + +GPP   +G    +     G  + GP++GP  +GGQ  +GP         P ++G HP
Sbjct: 958  DSRGPPNHHMGPMSERRHEQSGGPEHGPERGP-FRGGQDCRGP---------PDRRGPHP 1007

Query: 102  --PPPQGRPQG--PPQQGGHP-RPPRGRPQGPPQQ-----GGHQQGPPPPPPGKPQGPPP 151
              P    RP    P ++ GH  R   GR    PQ+     GG   GPP PP  +      
Sbjct: 1008 DFPDDFSRPDDFHPDKRFGHRLREFEGRGGPLPQEEKWRRGG--PGPPFPPDHREFSEGD 1065

Query: 152  QGGRPQGPP---QGQSP 165
              G  +GPP   +G+ P
Sbjct: 1066 GRGAARGPPGAWEGRRP 1082



 Score = 35.0 bits (79), Expect = 0.029
 Identities = 26/94 (27%), Positives = 37/94 (39%), Gaps = 14/94 (14%)

Query: 58   PSAGDGNQDDGPQQGPPQQGGQQQQGPPPPQGKPQ--------GPPQQGGHPPPPQGRP- 108
            P   +  + + P      +GG+ + GP P Q  P+        G    G H   P G P 
Sbjct: 1239 PGTSEHREMEAPGGPSEDRGGKGRGGPGPAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPP 1298

Query: 109  -QGPPQQGGHPRPPRGR----PQGPPQQGGHQQG 137
              G P +GG      GR      GPP++G  + G
Sbjct: 1299 GSGTPSRGGRSGSNWGRGSNMNSGPPRRGASRGG 1332



 Score = 33.1 bits (74), Expect = 0.11
 Identities = 29/95 (30%), Positives = 36/95 (37%), Gaps = 14/95 (14%)

Query: 35   GGDSEQFLDEERQGPPLGGQQSQPSAG-----DGNQDDGPQQGPPQQGGQQQQGPPPPQG 89
            GG SE    + R GP  G  Q  P +G     DG   DG  +  P  G       PP  G
Sbjct: 1251 GGPSEDRGGKGRGGP--GPAQRVPKSGRSSSLDGEHHDGYHRDEPFGG-------PPGSG 1301

Query: 90   KPQGPPQQGGHPPPPQGRPQGPPQQGGHPRPPRGR 124
             P    + G +         GPP++G      RGR
Sbjct: 1302 TPSRGGRSGSNWGRGSNMNSGPPRRGASRGGGRGR 1336



 Score = 30.4 bits (67), Expect = 0.73
 Identities = 25/97 (25%), Positives = 41/97 (42%), Gaps = 11/97 (11%)

Query: 69   PQQGPPQQGGQQQQGPPPPQGKPQGPPQQGGHPPPP--QGRPQGPPQQGGHPRPPRGRPQ 126
            PQ+   ++GG     PP  +   +G  +     PP   +GR  G  +    P  PR R +
Sbjct: 1040 PQEEKWRRGGPGPPFPPDHREFSEGDGRGAARGPPGAWEGRRPGDERFPRDPEDPRFRGR 1099

Query: 127  GPPQQGGHQQGPPP------PPPGKPQGPPPQGGRPQ 157
               ++   ++G PP      PP G+   P P+   P+
Sbjct: 1100 ---REESFRRGAPPRHEGRAPPRGRDGFPGPEDFGPE 1133


>gi|57165375 glutamate receptor, ionotropic, N-methyl
           D-aspartate-associated protein 1 [Homo sapiens]
          Length = 371

 Score = 73.2 bits (178), Expect = 1e-13
 Identities = 48/105 (45%), Positives = 51/105 (48%), Gaps = 11/105 (10%)

Query: 66  DDGPQQGPPQQGGQQQQGPP----PPQGKPQGPPQQGGHPPPPQGRPQGPPQQGGHPRPP 121
           D+ P   P   GG Q   PP    P  G P   P      P P G+P  P   G  P P 
Sbjct: 12  DNYPPPNPGYPGGPQPPMPPYAQPPYPGAPYPQPP---FQPSPYGQPGYP--HGPSPYPQ 66

Query: 122 RGRPQGPPQQGGHQQGPPPPPPGKPQGPPPQGGRPQGP-PQGQSP 165
            G PQGP  QGG+ QG P P  G PQGP PQGG PQGP PQ   P
Sbjct: 67  GGYPQGPYPQGGYPQG-PYPQEGYPQGPYPQGGYPQGPYPQSPFP 110



 Score = 63.5 bits (153), Expect = 8e-11
 Identities = 35/88 (39%), Positives = 42/88 (47%), Gaps = 1/88 (1%)

Query: 53  GQQSQPSAGDGNQDDGPQQGPPQQGGQQQQGPPPPQGKPQGPPQQGGHPPPPQGRPQGPP 112
           GQ   P         G  QGP  QGG  Q GP P +G PQGP  QGG+P  P  +   PP
Sbjct: 53  GQPGYPHGPSPYPQGGYPQGPYPQGGYPQ-GPYPQEGYPQGPYPQGGYPQGPYPQSPFPP 111

Query: 113 QQGGHPRPPRGRPQGPPQQGGHQQGPPP 140
              G P+   G+    PQ G +Q+  PP
Sbjct: 112 NPYGQPQVFPGQDPDSPQHGNYQEEGPP 139



 Score = 62.8 bits (151), Expect = 1e-10
 Identities = 49/113 (43%), Positives = 54/113 (47%), Gaps = 25/113 (22%)

Query: 69  PQQGPPQQGGQQQQGP--PPPQGKPQGPPQQGGHPPPPQGRPQGP-PQ----QGGHPRPP 121
           P   PP  G    Q P  P P G+P  P   G  P P  G PQGP PQ    QG  P P 
Sbjct: 31  PYAQPPYPGAPYPQPPFQPSPYGQPGYP--HGPSPYPQGGYPQGPYPQGGYPQG--PYPQ 86

Query: 122 RGRPQGPPQQGGHQQGP------PPPPPGKPQGPP------PQGG--RPQGPP 160
            G PQGP  QGG+ QGP      PP P G+PQ  P      PQ G  + +GPP
Sbjct: 87  EGYPQGPYPQGGYPQGPYPQSPFPPNPYGQPQVFPGQDPDSPQHGNYQEEGPP 139


>gi|57165373 glutamate receptor, ionotropic, N-methyl
           D-aspartate-associated protein 1 [Homo sapiens]
          Length = 371

 Score = 73.2 bits (178), Expect = 1e-13
 Identities = 48/105 (45%), Positives = 51/105 (48%), Gaps = 11/105 (10%)

Query: 66  DDGPQQGPPQQGGQQQQGPP----PPQGKPQGPPQQGGHPPPPQGRPQGPPQQGGHPRPP 121
           D+ P   P   GG Q   PP    P  G P   P      P P G+P  P   G  P P 
Sbjct: 12  DNYPPPNPGYPGGPQPPMPPYAQPPYPGAPYPQPP---FQPSPYGQPGYP--HGPSPYPQ 66

Query: 122 RGRPQGPPQQGGHQQGPPPPPPGKPQGPPPQGGRPQGP-PQGQSP 165
            G PQGP  QGG+ QG P P  G PQGP PQGG PQGP PQ   P
Sbjct: 67  GGYPQGPYPQGGYPQG-PYPQEGYPQGPYPQGGYPQGPYPQSPFP 110



 Score = 63.5 bits (153), Expect = 8e-11
 Identities = 35/88 (39%), Positives = 42/88 (47%), Gaps = 1/88 (1%)

Query: 53  GQQSQPSAGDGNQDDGPQQGPPQQGGQQQQGPPPPQGKPQGPPQQGGHPPPPQGRPQGPP 112
           GQ   P         G  QGP  QGG  Q GP P +G PQGP  QGG+P  P  +   PP
Sbjct: 53  GQPGYPHGPSPYPQGGYPQGPYPQGGYPQ-GPYPQEGYPQGPYPQGGYPQGPYPQSPFPP 111

Query: 113 QQGGHPRPPRGRPQGPPQQGGHQQGPPP 140
              G P+   G+    PQ G +Q+  PP
Sbjct: 112 NPYGQPQVFPGQDPDSPQHGNYQEEGPP 139



 Score = 62.8 bits (151), Expect = 1e-10
 Identities = 49/113 (43%), Positives = 54/113 (47%), Gaps = 25/113 (22%)

Query: 69  PQQGPPQQGGQQQQGP--PPPQGKPQGPPQQGGHPPPPQGRPQGP-PQ----QGGHPRPP 121
           P   PP  G    Q P  P P G+P  P   G  P P  G PQGP PQ    QG  P P 
Sbjct: 31  PYAQPPYPGAPYPQPPFQPSPYGQPGYP--HGPSPYPQGGYPQGPYPQGGYPQG--PYPQ 86

Query: 122 RGRPQGPPQQGGHQQGP------PPPPPGKPQGPP------PQGG--RPQGPP 160
            G PQGP  QGG+ QGP      PP P G+PQ  P      PQ G  + +GPP
Sbjct: 87  EGYPQGPYPQGGYPQGPYPQSPFPPNPYGQPQVFPGQDPDSPQHGNYQEEGPP 139


>gi|154448882 proline rich 4 (lacrimal) isoform 1 [Homo sapiens]
          Length = 147

 Score = 73.2 bits (178), Expect = 1e-13
 Identities = 38/94 (40%), Positives = 48/94 (51%)

Query: 5   LLSVALLAFSSAQDLNEDVSQEDVPLVISDGGDSEQFLDEERQGPPLGGQQSQPSAGDGN 64
           +L        S  ++  DV+ ED    I D  DS Q  D+  Q PP  G   +P    GN
Sbjct: 18  ILPAGTCCIYSRVEVFTDVNYEDFTFTIPDVEDSSQRPDQGPQRPPPEGLLPRPPGDSGN 77

Query: 65  QDDGPQQGPPQQGGQQQQGPPPPQGKPQGPPQQG 98
           QDDGPQQ PP+ GG  +  PPPP    Q PP++G
Sbjct: 78  QDDGPQQRPPKPGGHHRHPPPPPFQNQQRPPRRG 111



 Score = 55.1 bits (131), Expect = 3e-08
 Identities = 28/67 (41%), Positives = 34/67 (50%), Gaps = 2/67 (2%)

Query: 95  PQQGGHPPPPQGRPQGPPQQGGHPRPPRGRPQGPPQQGGHQQGPPPPPPGKPQGPPPQGG 154
           P QG   PPP+G    PP   G+     G  Q PP+ GGH + PPPPP    Q PP +G 
Sbjct: 55  PDQGPQRPPPEGLLPRPPGDSGNQDD--GPQQRPPKPGGHHRHPPPPPFQNQQRPPRRGH 112

Query: 155 RPQGPPQ 161
           R    P+
Sbjct: 113 RQLSLPR 119



 Score = 43.5 bits (101), Expect = 8e-05
 Identities = 28/79 (35%), Positives = 33/79 (41%), Gaps = 10/79 (12%)

Query: 58  PSAGDGNQDDGPQQGPPQQGGQQQQGPPPPQGKPQGPPQQGGHPPPPQGRPQGPPQQGGH 117
           P   D +Q   P QGP        Q PPP    P+ P   G     PQ RP  P     H
Sbjct: 46  PDVEDSSQR--PDQGP--------QRPPPEGLLPRPPGDSGNQDDGPQQRPPKPGGHHRH 95

Query: 118 PRPPRGRPQGPPQQGGHQQ 136
           P PP  + Q  P + GH+Q
Sbjct: 96  PPPPPFQNQQRPPRRGHRQ 114


>gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]
          Length = 502

 Score = 70.9 bits (172), Expect = 5e-13
 Identities = 43/106 (40%), Positives = 46/106 (43%), Gaps = 12/106 (11%)

Query: 65  QDDGPQQGPPQQGGQQQQGPPPPQGK-----PQGPPQQGGHPPPPQGRPQGPPQQGGHPR 119
           Q+  P   PP +GG Q   PP   G      P  P   G  PPPP  R   PP +GG P 
Sbjct: 310 QEPLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPPPPGRGGPPP 369

Query: 120 PP-----RGRPQGPPQQGGHQQGPPPPPPGKPQGPPPQGGRPQGPP 160
           PP     R  P  PP  G    GPP PPP  P  PPP  G    PP
Sbjct: 370 PPPPATGRSGPLPPPPPGAG--GPPMPPPPPPPPPPPSSGNGPAPP 413



 Score = 63.5 bits (153), Expect = 8e-11
 Identities = 53/148 (35%), Positives = 60/148 (40%), Gaps = 26/148 (17%)

Query: 32  ISDGGDSEQFLDEERQGPPL---------GGQQSQPSAGDGNQD-DGPQQGPPQQGGQQQ 81
           I D G  E    E R+  PL         G Q  +P    GN+   GP   PP   G   
Sbjct: 294 IEDQGGLEAVRQEMRRQEPLPPPPPPSRGGNQLPRPPIVGGNKGRSGPL--PPVPLGI-- 349

Query: 82  QGPPPPQGKPQGPPQQGGHPPPPQ---GR----PQGPPQQGGHPRPPRGRPQGPPQQGGH 134
             PPPP  +   PP +GG PPPP    GR    P  PP  GG P PP   P  PP   G+
Sbjct: 350 -APPPPTPRGPPPPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGN 408

Query: 135 QQGPPPPPPGKPQGPPPQGGRPQGPPQG 162
                P PP  P    P GG   G  +G
Sbjct: 409 G----PAPPPLPPALVPAGGLAPGGGRG 432



 Score = 59.3 bits (142), Expect = 1e-09
 Identities = 44/117 (37%), Positives = 54/117 (46%), Gaps = 26/117 (22%)

Query: 65  QDDGPQQGPPQQGGQQQQGPPPPQGKPQGPPQQGGH--PPPP-----QGR--PQGPPQQG 115
           +D G  +   Q+  +Q+  PPPP      PP +GG+  P PP     +GR  P  P   G
Sbjct: 295 EDQGGLEAVRQEMRRQEPLPPPP------PPSRGGNQLPRPPIVGGNKGRSGPLPPVPLG 348

Query: 116 GHPRPPRGRPQGPPQQGGHQQGPPPPPPGK-------PQGPPPQGGRPQGPPQGQSP 165
             P PP   P+GPP  G  + GPPPPPP         P  PP  GG P  PP    P
Sbjct: 349 IAPPPPT--PRGPPPPG--RGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPP 401



 Score = 49.7 bits (117), Expect = 1e-06
 Identities = 37/109 (33%), Positives = 39/109 (35%), Gaps = 7/109 (6%)

Query: 47  QGPP---LGGQQSQPSAGDGNQDDGPQQGPPQQGGQQQQGPPPPQGKPQGPPQQGGHPPP 103
           +GPP    GG    P    G    GP   PP   G     PPPP   P  PP  G  P P
Sbjct: 357 RGPPPPGRGGPPPPPPPATGRS--GPLPPPPPGAGGPPMPPPPPPPPP--PPSSGNGPAP 412

Query: 104 PQGRPQGPPQQGGHPRPPRGRPQGPPQQGGHQQGPPPPPPGKPQGPPPQ 152
           P   P   P  G  P   RG      +QG      P  P      PPPQ
Sbjct: 413 PPLPPALVPAGGLAPGGGRGALLDQIRQGIQLNKTPGAPESSALQPPPQ 461



 Score = 33.9 bits (76), Expect = 0.066
 Identities = 27/80 (33%), Positives = 34/80 (42%), Gaps = 11/80 (13%)

Query: 70  QQGPPQQGGQQQQGPPPPQGKPQGPPQQGGHPPPPQGRPQGPPQQGGHPRPPRGRP---- 125
           Q+   +Q G ++Q PPPP   P    ++GG PP P   P G   QGG P  P        
Sbjct: 146 QKRNQRQSGDRRQLPPPP--TPANEERRGGLPPLPL-HPGG--DQGGPPVGPLSLGLATV 200

Query: 126 --QGPPQQGGHQQGPPPPPP 143
             Q P       +G P P P
Sbjct: 201 DIQNPDITSSRYRGLPAPGP 220



 Score = 30.0 bits (66), Expect = 0.95
 Identities = 17/40 (42%), Positives = 18/40 (45%), Gaps = 7/40 (17%)

Query: 130 QQGGHQQGPPPPPP-------GKPQGPPPQGGRPQGPPQG 162
           Q G  +Q PPPP P       G P  P   GG   GPP G
Sbjct: 152 QSGDRRQLPPPPTPANEERRGGLPPLPLHPGGDQGGPPVG 191


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 70.9 bits (172), Expect = 5e-13
 Identities = 59/166 (35%), Positives = 65/166 (39%), Gaps = 37/166 (22%)

Query: 35  GGDSEQFLDEERQGPP-LGGQQSQPSAGDGNQDDGPQQGPPQQGGQQQQGPPPPQGKPQG 93
           GG     L + R  PP +G  Q++   G G    GP+   P     QQQ  PPPQ  P  
Sbjct: 21  GGGGRGGLHDFRSPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPP-- 78

Query: 94  PPQQGGHPPPP------QGRPQGPPQ--------QGGHPRPPRGR---------PQGPPQ 130
           P Q   H PPP      Q +P  PPQ        QG  P P  G          P  PP 
Sbjct: 79  PQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPT 138

Query: 131 QG---GHQQGP---PPP-----PPGKPQGPPPQGGRPQGPPQGQSP 165
            G   G   GP   PPP     PPG P   PP  G P  PPQ   P
Sbjct: 139 SGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGP 184



 Score = 70.5 bits (171), Expect = 6e-13
 Identities = 58/155 (37%), Positives = 59/155 (38%), Gaps = 42/155 (27%)

Query: 49  PPLGGQQSQPSAGDGNQDDGPQQGPPQ------QGGQQQQGPPPPQ--GKP---QGP--- 94
           PP   QQ QP      Q   PQQ PP       Q  QQQQ PPPPQ   KP   QGP   
Sbjct: 63  PPPHQQQQQPPP----QQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPA 118

Query: 95  PQQGGHPPPPQGRPQGPPQQGGHP-----------------RPPRGRPQGPPQQG----G 133
           P  G  PP     P   P   G P                  PP   P  PP  G     
Sbjct: 119 PGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTP 178

Query: 134 HQQGPPPPPPGKPQGP---PPQGGRPQGPPQGQSP 165
            Q G PPPPP    GP   P QG  P GP  G+ P
Sbjct: 179 PQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMP 213



 Score = 65.5 bits (158), Expect = 2e-11
 Identities = 52/134 (38%), Positives = 58/134 (43%), Gaps = 27/134 (20%)

Query: 49  PPLGGQQSQPSAGDGNQDDGPQQGPPQQGGQQQQGPPPP----QGKPQGPPQQGGHPPPP 104
           PP  G  + P +G G     P   PP        G PPP     G P  PPQ GG PPPP
Sbjct: 136 PPTSG--APPGSGPG-----PTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPP 188

Query: 105 QGRP-QGP-PQQGGHPRPPRG--RPQGPPQQGGHQQGPP---PPPP----GKPQG----- 148
              P  GP P+QG  P  P+G   P GP   GG     P   P PP    G+P+G     
Sbjct: 189 AAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHH 248

Query: 149 PPPQGGRPQGPPQG 162
           PP      QGPP G
Sbjct: 249 PPYHQQHHQGPPPG 262



 Score = 63.9 bits (154), Expect = 6e-11
 Identities = 50/150 (33%), Positives = 60/150 (40%), Gaps = 24/150 (16%)

Query: 37  DSEQFLDEERQGPPLGGQQSQPSAGDGNQDDGPQQGPPQQGGQQQQGPPPP--------- 87
           DS + +  +  GP  G   + P++        P  G P   G      PPP         
Sbjct: 105 DSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGA 164

Query: 88  -------QGKPQGPPQQGGHPPPPQGRP-QGP-PQQGGHPRPPRG--RPQGPPQQGGHQQ 136
                   G P  PPQ GG PPPP   P  GP P+QG  P  P+G   P GP   GG   
Sbjct: 165 PPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGL 224

Query: 137 GPP---PPPPGKPQGPPPQGGRPQGPPQGQ 163
             P   P PP +  G  P+GGR   PP  Q
Sbjct: 225 STPGGHPKPPHR-GGGEPRGGRQHHPPYHQ 253



 Score = 62.4 bits (150), Expect = 2e-10
 Identities = 39/98 (39%), Positives = 43/98 (43%), Gaps = 12/98 (12%)

Query: 49  PPLGGQQSQPSAGDGNQDDGPQQGPPQQGGQQQQGPPPPQGKPQGPPQQGGHP--PPPQG 106
           PP  G    P A       GP+QGP   G        P  GK  G P+ GG P    P G
Sbjct: 178 PPQAGGPPPPPAAVPGPGPGPKQGPGPGG--------PKGGKMPGGPKPGGGPGLSTPGG 229

Query: 107 RPQGPPQQGGHPRPPRGRPQGPPQQGGHQQGPPPPPPG 144
            P+ P + GG PR   GR   PP    H QGPPP  PG
Sbjct: 230 HPKPPHRGGGEPRG--GRQHHPPYHQQHHQGPPPGGPG 265



 Score = 34.7 bits (78), Expect = 0.038
 Identities = 21/51 (41%), Positives = 24/51 (47%), Gaps = 8/51 (15%)

Query: 120 PPRG----RPQGPPQQGGHQQGPPPPPPGKPQGPPPQGGRPQGPPQGQSPQ 166
           PP G    + +GP   G  Q GP PP P     PPP   + Q PPQ   PQ
Sbjct: 34  PPPGMGLNQNRGPMGPGPGQSGPKPPIPP----PPPHQQQQQPPPQQPPPQ 80



 Score = 30.0 bits (66), Expect = 0.95
 Identities = 25/78 (32%), Positives = 27/78 (34%), Gaps = 8/78 (10%)

Query: 77  GGQQQQGPPPPQGKPQGPPQQGGHPPPPQGRPQGPP------QQGGHPRPPRGRPQGPPQ 130
           GG    G P   G  + PP  GG     +  P  PP        G   R  R    G   
Sbjct: 615 GGAMNMGDPYGSGGQKFPPLGGGGGIGYEANPGVPPATMSGSMMGSDMRTERFGQGGAGP 674

Query: 131 QGGHQQGPPPPPPGKPQG 148
            GG  QGP    PG P G
Sbjct: 675 VGG--QGPRGMGPGTPAG 690


>gi|38150007 small nuclear ribonucleoprotein polypeptide B/B'
           isoform B' [Homo sapiens]
          Length = 240

 Score = 70.5 bits (171), Expect = 6e-13
 Identities = 48/128 (37%), Positives = 58/128 (45%), Gaps = 25/128 (19%)

Query: 35  GGDSEQFLDEERQGPPLGGQQSQPSAGDGNQDDGPQQGPPQQGGQQQQGPPPPQGKPQGP 94
           GG S+Q +  + +G       +  ++  G     P Q PP +GG     PPPP G+   P
Sbjct: 135 GGPSQQVMTPQGRGTVAAAAAAATASIAG----APTQYPPGRGG-----PPPPMGRGAPP 185

Query: 95  PQQGGHPP---PPQGRPQGPPQQGGHPRPPRGRPQGPPQQGGHQQGPPPPPPGKPQGPPP 151
           P   G PP   PP G P G P       P RG P G P  G       PPPPG  +GPPP
Sbjct: 186 PGMMGPPPGMRPPMGPPMGIP-------PGRGTPMGMPPPGMR-----PPPPGM-RGPPP 232

Query: 152 QGGRPQGP 159
            G RP  P
Sbjct: 233 PGMRPPRP 240



 Score = 41.6 bits (96), Expect = 3e-04
 Identities = 43/145 (29%), Positives = 46/145 (31%), Gaps = 66/145 (45%)

Query: 82  QGPPPPQ-----------------GKPQGPPQQGGHPPP--------------------- 103
           +GPPP                   G+  G     G P P                     
Sbjct: 83  EGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVM 142

Query: 104 -PQGR------------------PQGPPQQGGHPRPPRGRPQGPPQQGGHQQGPPP---P 141
            PQGR                   Q PP +GG P PP GR   PP       GPPP   P
Sbjct: 143 TPQGRGTVAAAAAAATASIAGAPTQYPPGRGG-PPPPMGRGAPPP----GMMGPPPGMRP 197

Query: 142 PPGKPQGPPPQGGRPQG-PPQGQSP 165
           P G P G PP  G P G PP G  P
Sbjct: 198 PMGPPMGIPPGRGTPMGMPPPGMRP 222


>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
          Length = 424

 Score = 70.1 bits (170), Expect = 8e-13
 Identities = 54/145 (37%), Positives = 55/145 (37%), Gaps = 33/145 (22%)

Query: 49  PPLGGQQSQPSAGDGNQDDG---PQQGPPQ--QGGQQQQGPPPPQGKPQGPPQQGGHPPP 103
           PP        S G G    G   P   PP     G    G PP    P  PP   GH PP
Sbjct: 217 PPSAPNPVVSSLGSGLPPPGMPPPGSFPPPVPPPGALPPGIPPAMPPPPMPPGAAGHGPP 276

Query: 104 PQGRP-QGPPQQGG---HPRPPRGRPQ---------------------GPPQQGGHQQGP 138
             G P  G P  G    HP PP G P                      GPP  GG  Q P
Sbjct: 277 SAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGG--QPP 334

Query: 139 PPPPPGKPQ-GPPPQGGRPQGPPQG 162
           P PPPG P  GPPP G  P+GPP G
Sbjct: 335 PRPPPGMPHPGPPPMGMPPRGPPFG 359



 Score = 66.6 bits (161), Expect = 9e-12
 Identities = 48/131 (36%), Positives = 55/131 (41%), Gaps = 18/131 (13%)

Query: 48  GPPLGGQQSQPSAGDGNQDDG-PQQGPPQQGGQQQQGPPP----PQGKPQGPPQQGGHPP 102
           G P  G      A  G    G P  GPP  GGQ    PPP    P   P G P +G    
Sbjct: 300 GMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQPPPRPPPGMPHPGPPPMGMPPRGPPFG 359

Query: 103 PPQGRPQGPPQQGGHPRPP-------RGRPQGPPQQGGHQQGPPPPPPGKPQGPPPQGGR 155
            P G P   P  G    PP        G P+ PP   G+Q+GP PPP   P+ P P    
Sbjct: 360 SPMGHPGPMPPHGMRGPPPLMPPHGYTGPPRPPPY--GYQRGPLPPPRPTPRPPVP---- 413

Query: 156 PQGPPQGQSPQ 166
           P+GP +G  PQ
Sbjct: 414 PRGPLRGPLPQ 424



 Score = 62.0 bits (149), Expect = 2e-10
 Identities = 49/124 (39%), Positives = 51/124 (41%), Gaps = 22/124 (17%)

Query: 48  GPPLGGQQS--QPSAGDGNQDDGPQQGPPQQGGQQQQ----GPPPPQGKPQGPPQQGGHP 101
           GPP  G      P  G  +    P  G P  G  Q Q    GP        GPP  GG P
Sbjct: 274 GPPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQP 333

Query: 102 PP--PQGRPQ-GPPQQGGHPRPPRGRPQGPPQQGGHQQGPPPPPPGKPQGPPPQGGRPQG 158
           PP  P G P  GPP  G    PPRG P G P   GH   P P PP   +GPPP       
Sbjct: 334 PPRPPPGMPHPGPPPMG---MPPRGPPFGSPM--GH---PGPMPPHGMRGPPPL-----M 380

Query: 159 PPQG 162
           PP G
Sbjct: 381 PPHG 384


>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
           sapiens]
          Length = 505

 Score = 68.6 bits (166), Expect = 2e-12
 Identities = 55/168 (32%), Positives = 64/168 (38%), Gaps = 34/168 (20%)

Query: 10  LLAFSSAQDLNEDVSQEDVPLVISDGGDSEQFLDEERQGPPLGGQQSQPSAGDGNQDDGP 69
           +   S AQ  + + S+     +   GG      +  RQ PP       PS G      GP
Sbjct: 238 MCGISEAQLKDRETSKVIYDFIEKTGGVEAVKNELRRQAPP----PPPPSRG------GP 287

Query: 70  QQGPPQQGGQQQQGPPPP----QGKPQGPPQQG---GHPPPPQGRPQ----GPPQQGGHP 118
              PP        GPPPP    +G P  PP +      PPPP  RP      PP    +P
Sbjct: 288 PPPPPPP---HNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYP 344

Query: 119 RPP----RGRPQGPPQQGGHQQG------PPPPPPGKPQGPPPQGGRP 156
            PP       P GPP       G      PPPPPP  P GPPP  G P
Sbjct: 345 PPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPGPPPPPGLP 392



 Score = 63.2 bits (152), Expect = 1e-10
 Identities = 37/99 (37%), Positives = 41/99 (41%), Gaps = 24/99 (24%)

Query: 80  QQQGPPPPQGKPQGPPQQGGHPPPPQGRPQGPPQQGGHPRPP---RGRPQGPPQQGGHQQ 136
           ++Q PPPP      PP +GG PPPP      PP   G P PP   RG P  PP +     
Sbjct: 273 RRQAPPPP------PPSRGGPPPPPP-----PPHNSGPPPPPARGRGAPPPPPSRAPTAA 321

Query: 137 GPPPPP----------PGKPQGPPPQGGRPQGPPQGQSP 165
            PPPPP          P     PPP    P   P G  P
Sbjct: 322 PPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPP 360



 Score = 61.2 bits (147), Expect = 4e-10
 Identities = 41/110 (37%), Positives = 44/110 (40%), Gaps = 18/110 (16%)

Query: 69  PQQGPPQQGGQQQQGPPPPQGKPQGPPQQG-GHPPPPQGR------PQGPPQQGGH--PR 119
           P   PP +GG     PPP    P  PP +G G PPPP  R      P  PP +     P 
Sbjct: 277 PPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPP 336

Query: 120 PPRGRPQGPPQQGGHQQGP--PPPPPGKPQG-------PPPQGGRPQGPP 160
           PP  R   PP        P  PPPPP    G       PPP    P GPP
Sbjct: 337 PPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPGPP 386



 Score = 38.9 bits (89), Expect = 0.002
 Identities = 22/63 (34%), Positives = 22/63 (34%), Gaps = 11/63 (17%)

Query: 73  PPQQGGQQQQGPPPPQGKPQGPPQQGGHPPPPQGRPQGPPQQGGHPRPPRGRPQGPPQQG 132
           PP        GPPPP     G       PPPP   P GPP            P G P  G
Sbjct: 347 PPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPGPPP-----------PPGLPSDG 395

Query: 133 GHQ 135
            HQ
Sbjct: 396 DHQ 398



 Score = 37.0 bits (84), Expect = 0.008
 Identities = 25/72 (34%), Positives = 26/72 (36%), Gaps = 9/72 (12%)

Query: 49  PPLGGQQSQPSAGDGNQDDGPQQGPPQQGGQQQQGPPPPQGKPQGPPQQGGHPPPPQGRP 108
           PP       P A   +   GP   PP   G     PPPP      PP   G PPPP    
Sbjct: 338 PPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPP----PPPPPGPPPPP---- 389

Query: 109 QGPPQQGGHPRP 120
            G P  G H  P
Sbjct: 390 -GLPSDGDHQVP 400


>gi|50428940 mediator complex subunit 25 [Homo sapiens]
          Length = 747

 Score = 68.2 bits (165), Expect = 3e-12
 Identities = 58/152 (38%), Positives = 69/152 (45%), Gaps = 36/152 (23%)

Query: 39  EQFLDEERQGPPLGGQQSQPSAGDGNQDDGPQQGPPQQGGQQQQGPPP-PQGK-----PQ 92
           +Q L+++++G  +GGQQ+ P  G   +D    Q  P Q   Q + P P PQG        
Sbjct: 549 QQKLEQQQRG--MGGQQAPPGLGPILED----QARPSQNLLQLRPPQPQPQGTVGASGAT 602

Query: 93  GPPQQGGHPPPPQGRPQGPPQQGGHPRPPRG--RPQGP---PQQGGHQQGPPPP------ 141
           G PQ  G   PP G PQGPP     P PP    RPQ P   PQ       PPPP      
Sbjct: 603 GQPQPQGTAQPPPGAPQGPPGAASGPPPPGPILRPQNPGANPQLRSLLLNPPPPQTGVPP 662

Query: 142 ---------PPGKPQ--GPPPQG-GRPQ-GPP 160
                    PPG P    PP QG G+PQ GPP
Sbjct: 663 PQASLHHLQPPGAPALLPPPHQGLGQPQLGPP 694



 Score = 56.6 bits (135), Expect = 9e-09
 Identities = 47/123 (38%), Positives = 49/123 (39%), Gaps = 20/123 (16%)

Query: 49  PPLGGQQSQPSAGDGNQDDGPQQGPPQQGGQQQQ-----GPPPPQGKPQGPPQQGGHPPP 103
           PP G  Q  P A  G    GP   P   G   Q       PPPPQ     PPQ   H   
Sbjct: 613 PPPGAPQGPPGAASGPPPPGPILRPQNPGANPQLRSLLLNPPPPQTGVP-PPQASLHHLQ 671

Query: 104 PQGRPQ--GPPQQG-GHPR--PPRGRPQGPPQQGGHQQGPPPPP-------PGKPQGPPP 151
           P G P    PP QG G P+  PP   P  PP Q    Q PP  P        G P+GP P
Sbjct: 672 PPGAPALLPPPHQGLGQPQLGPPLLHP--PPAQSWPAQLPPRAPLPGQMLLSGGPRGPVP 729

Query: 152 QGG 154
           Q G
Sbjct: 730 QPG 732



 Score = 37.4 bits (85), Expect = 0.006
 Identities = 34/106 (32%), Positives = 38/106 (35%), Gaps = 23/106 (21%)

Query: 79  QQQQGPPPPQGKPQGP-----PQQGGHPPPPQGRPQG----------------PPQQGGH 117
           Q +Q  P P   P G      PQQ   P PPQ +  G                  Q+ G 
Sbjct: 240 QSKQPVPLPPAAPSGATLSAAPQQPLPPVPPQYQVPGNLSAAQVAAQNAVEAAKNQKAG- 298

Query: 118 PRPPRGRPQGPPQQGGHQQGPPPPPPGKPQGPPPQGGRPQGPPQGQ 163
              PR  P  P QQ     GPP      PQ PP   G P+ PP  Q
Sbjct: 299 -LGPRFSPITPLQQAAPGVGPPFSQAPAPQLPPGPPGAPKPPPASQ 343



 Score = 32.7 bits (73), Expect = 0.15
 Identities = 26/92 (28%), Positives = 30/92 (32%), Gaps = 10/92 (10%)

Query: 65  QDDGPQQGPPQQGGQQQQGPPPPQGKPQGPPQQGGHPPPPQGRPQ-GPPQQGGHPRPPRG 123
           Q   P  GPP       Q PP P G P+         PPP  +P        G    P  
Sbjct: 310 QQAAPGVGPPFSQAPAPQLPPGPPGAPK---------PPPASQPSLVSTVAPGSGLAPTA 360

Query: 124 RPQGPPQQGGHQQGPPPPPPGKPQGPPPQGGR 155
           +P  P   G    G    P     G P  GG+
Sbjct: 361 QPGAPSMAGTVAPGGVSGPSPAQLGAPALGGQ 392



 Score = 28.1 bits (61), Expect = 3.6
 Identities = 24/88 (27%), Positives = 30/88 (34%), Gaps = 11/88 (12%)

Query: 81  QQGPPPPQGKPQGPPQQGGHPPPPQGRPQG---PPQQGGHPRPPRGRPQGPPQQGGHQQG 137
           ++  PP   +P  PP      P      +G   P   G  P P + +   P         
Sbjct: 196 EKAAPPALLEPLQPPTDVSQDPRHMVLVRGLVLPVGGGSAPGPLQSKQPVPL-------- 247

Query: 138 PPPPPPGKPQGPPPQGGRPQGPPQGQSP 165
           PP  P G      PQ   P  PPQ Q P
Sbjct: 248 PPAAPSGATLSAAPQQPLPPVPPQYQVP 275


>gi|50511941 EMI domain containing 1 [Homo sapiens]
          Length = 443

 Score = 66.2 bits (160), Expect = 1e-11
 Identities = 49/141 (34%), Positives = 55/141 (39%), Gaps = 29/141 (20%)

Query: 45  ERQGPPLGGQQSQPSAGDGNQDD-----------GPQQGPPQQGGQQQQGPPPPQGKPQG 93
           E   P  G   +Q S GDG   D           GP+     +G    +GPP PQG P  
Sbjct: 174 EDPAPLWGPPPAQGSPGDGGLQDQVGAWGLPGPTGPKGDAGSRGPMGMRGPPGPQGPPGS 233

Query: 94  PPQQGGHPPPPQGRPQGPPQQGGHPRPPRGRPQGPPQQGGHQQGPP-------------P 140
           P + G    P +  P GPP   G P PP   P GPP     Q G P             P
Sbjct: 234 PGRAGAVGTPGERGPPGPPGPPGPPGPP--APVGPPHARISQHGDPLLSNTFTETNNHWP 291

Query: 141 PPPGKPQGPP-PQGGRPQGPP 160
             P  P GPP P G  P GPP
Sbjct: 292 QGPTGPPGPPGPMG--PPGPP 310



 Score = 50.1 bits (118), Expect = 9e-07
 Identities = 48/137 (35%), Positives = 53/137 (38%), Gaps = 24/137 (17%)

Query: 47  QGPPLGGQQSQPSAGDGNQDDGPQQGPPQQGGQQQQGPPPPQGKPQGPPQQGGHPPP--- 103
           QGPP  G   +  A     + GP  GPP   G    GPP P G P     Q G P     
Sbjct: 228 QGPP--GSPGRAGAVGTPGERGPP-GPPGPPGPP--GPPAPVGPPHARISQHGDPLLSNT 282

Query: 104 --------PQGR--PQGPPQQGGHPRPPRGRPQGPPQQGGHQQGPPPPPPGKPQGPPPQG 153
                   PQG   P GPP   G P PP   P G P   GH   P P  P    G P + 
Sbjct: 283 FTETNNHWPQGPTGPPGPPGPMGPPGPPG--PTGVPGSPGHIGPPGPTGPKGISGHPGEK 340

Query: 154 G----RPQGPPQGQSPQ 166
           G    R +  PQG + Q
Sbjct: 341 GERGLRGEPGPQGSAGQ 357



 Score = 44.3 bits (103), Expect = 5e-05
 Identities = 32/77 (41%), Positives = 33/77 (42%), Gaps = 7/77 (9%)

Query: 72  GPPQQGGQQQQGPPPPQGKPQGPPQQGGHPPPPQGRPQGPPQQGGHP--RPPRGRPQGPP 129
           GPP   G    GPP P G P G P   GH  PP   P GP    GHP  +  RG    P 
Sbjct: 296 GPPGPPGPM--GPPGPPG-PTGVPGSPGHIGPP--GPTGPKGISGHPGEKGERGLRGEPG 350

Query: 130 QQGGHQQGPPPPPPGKP 146
            QG   Q   P P G P
Sbjct: 351 PQGSAGQRGEPGPKGDP 367



 Score = 39.3 bits (90), Expect = 0.002
 Identities = 35/86 (40%), Positives = 37/86 (43%), Gaps = 19/86 (22%)

Query: 79  QQQQGPPPPQGKPQGPPQQGGHPPPPQGRPQGPPQQGGHPRPPRGRPQGPPQQGGH---- 134
           Q   GPP P G P GPP     PP P G P  P    GH  PP   P GP    GH    
Sbjct: 292 QGPTGPPGPPG-PMGPP----GPPGPTGVPGSP----GHIGPP--GPTGPKGISGHPGEK 340

Query: 135 -QQGPPPPPPGKPQGPPPQGGRPQGP 159
            ++G    P   PQG   Q G P GP
Sbjct: 341 GERGLRGEP--GPQGSAGQRGEP-GP 363



 Score = 37.7 bits (86), Expect = 0.005
 Identities = 30/96 (31%), Positives = 34/96 (35%), Gaps = 12/96 (12%)

Query: 81  QQGPPPPQGKPQGPPQQGGHPPPPQGRPQG---PPQQGGHPRPPRGRPQGPPQQGGHQQG 137
           +Q  PP    P+ P    G PPP QG P       Q G    P    P+G     G    
Sbjct: 163 EQPVPPTPATPEDPAPLWG-PPPAQGSPGDGGLQDQVGAWGLPGPTGPKGDAGSRGPMGM 221

Query: 138 PPPPPPGKPQGPPPQGGR--------PQGPPQGQSP 165
             PP P  P G P + G         P GPP    P
Sbjct: 222 RGPPGPQGPPGSPGRAGAVGTPGERGPPGPPGPPGP 257



 Score = 31.2 bits (69), Expect = 0.43
 Identities = 28/112 (25%), Positives = 40/112 (35%), Gaps = 10/112 (8%)

Query: 23  VSQEDVPLVISDGGDSEQFLDEERQGPPLGGQQSQPSAGDGNQDDGPQQGPPQQGGQQQQ 82
           +SQ   PL+ +   ++     +   GPP       P         GP   P   G     
Sbjct: 271 ISQHGDPLLSNTFTETNNHWPQGPTGPP-----GPPGPMGPPGPPGPTGVPGSPGHIGPP 325

Query: 83  GPPPPQGKPQGPPQQGGHPPPPQGRPQGPPQQGGHPRPPRGRPQGPPQQGGH 134
           GP  P+G    P ++G      +  PQG   Q G P      P+G P +  H
Sbjct: 326 GPTGPKGISGHPGEKGERGLRGEPGPQGSAGQRGEP-----GPKGDPGEKSH 372


>gi|56117846 synovial sarcoma translocation, chromosome 18 isoform 1
           [Homo sapiens]
          Length = 418

 Score = 64.7 bits (156), Expect = 3e-11
 Identities = 63/145 (43%), Positives = 67/145 (46%), Gaps = 40/145 (27%)

Query: 47  QGPPLG-GQQSQPSAGDGNQDDGPQQGP-PQQG--------------------GQQQ--- 81
           QGPP G  QQ  P   DG+ D G QQ   P+QG                    GQQQ   
Sbjct: 280 QGPPEGMNQQYYP---DGHNDYGYQQPSYPEQGYDRPYEDSSQHYYEGGNSQYGQQQDAY 336

Query: 82  QGPPPPQGKP---QGPPQQGGHPPPPQGRPQGPPQQGGHPRPPRGRPQGPPQQGGHQQGP 138
           QGPPP QG P   Q  P Q G+P   QG   GP Q G  P+ P   PQG  QQ G   G 
Sbjct: 337 QGPPPQQGYPPQQQQYPGQQGYPGQQQG--YGPSQGGPGPQYP-NYPQGQGQQYG---GY 390

Query: 139 PPPPPGKPQGPPPQGGRPQGPPQGQ 163
            P  PG PQ PP Q  RP G  QGQ
Sbjct: 391 RPTQPGPPQ-PPQQ--RPYGYDQGQ 412



 Score = 52.4 bits (124), Expect = 2e-07
 Identities = 48/142 (33%), Positives = 54/142 (38%), Gaps = 39/142 (27%)

Query: 47  QGPPLGGQQSQPSAGDGNQDDGPQQGP-------------PQQGGQQQQGPPPPQGKPQG 93
           QG P+G    +P     N    P QGP             PQ GGQ  QG  PP G   G
Sbjct: 183 QGQPMGNYGPRP-----NMSMQPNQGPMMHQQPPSQQYNMPQGGGQHYQGQQPPMGM-MG 236

Query: 94  PPQQGGHPPPPQGRPQGPPQQGGHPRPPRGRPQGPPQQGGHQQ---------GPPPPPPG 144
              QG H     G+ Q PP      RPP+   QGPPQQ   Q+         G   PP G
Sbjct: 237 QVNQGNH---MMGQRQIPPY-----RPPQ---QGPPQQYSGQEDYYGDQYSHGGQGPPEG 285

Query: 145 KPQGPPPQGGRPQGPPQGQSPQ 166
             Q   P G    G  Q   P+
Sbjct: 286 MNQQYYPDGHNDYGYQQPSYPE 307



 Score = 45.8 bits (107), Expect = 2e-05
 Identities = 51/161 (31%), Positives = 59/161 (36%), Gaps = 43/161 (26%)

Query: 47  QGPPLG--GQQSQPSAGDGNQD----DGPQQGPPQQ-GGQQQQGPPPPQGKPQGPPQQGG 99
           Q PP+G  GQ +Q +   G +       PQQGPPQQ  GQ+           QGPP+   
Sbjct: 228 QQPPMGMMGQVNQGNHMMGQRQIPPYRPPQQGPPQQYSGQEDYYGDQYSHGGQGPPEGMN 287

Query: 100 HPPPPQGRPQGPPQQGGHPRPPRGRP-----------------------QGPPQQGGH-- 134
               P G      QQ  +P     RP                       QGPP Q G+  
Sbjct: 288 QQYYPDGHNDYGYQQPSYPEQGYDRPYEDSSQHYYEGGNSQYGQQQDAYQGPPPQQGYPP 347

Query: 135 -------QQGPPPPPPGKPQGPPPQGGRPQGP--PQGQSPQ 166
                  QQG P    G   GP   G  PQ P  PQGQ  Q
Sbjct: 348 QQQQYPGQQGYPGQQQG--YGPSQGGPGPQYPNYPQGQGQQ 386



 Score = 34.7 bits (78), Expect = 0.038
 Identities = 26/71 (36%), Positives = 27/71 (38%), Gaps = 12/71 (16%)

Query: 85  PPPQGKPQGP--PQQGGHPPPPQGR--PQGPPQQGGHPRPPRGRPQGPPQQGGHQQGPPP 140
           PP Q  P GP    Q G PPPP+    P      GG P P         Q  G   GP  
Sbjct: 78  PPTQNMPMGPGGMNQSGPPPPPRSHNMPSDGMVGGGPPAPHMQN-----QMNGQMPGPNH 132

Query: 141 PPPGKPQGPPP 151
            P    QGP P
Sbjct: 133 MP---MQGPGP 140



 Score = 32.7 bits (73), Expect = 0.15
 Identities = 25/67 (37%), Positives = 25/67 (37%), Gaps = 7/67 (10%)

Query: 102 PPPQGRPQGP--PQQGGHPRPPRGRPQGPPQQGGHQQGPPPPPPGKP---QGPPPQGGRP 156
           PP Q  P GP    Q G P PPR      P  G    GPP P        Q P P     
Sbjct: 78  PPTQNMPMGPGGMNQSGPPPPPRS--HNMPSDGMVGGGPPAPHMQNQMNGQMPGPNHMPM 135

Query: 157 QGPPQGQ 163
           QGP   Q
Sbjct: 136 QGPGPNQ 142



 Score = 32.3 bits (72), Expect = 0.19
 Identities = 28/99 (28%), Positives = 31/99 (31%), Gaps = 8/99 (8%)

Query: 69  PQQGPPQQGGQQQQGPPPPQGKPQGPPQQ---GGHPPPPQGRPQGPPQQGGHPRPPRGRP 125
           P Q  P   G   Q  PPP  +    P     GG PP P  + Q     G  P P     
Sbjct: 79  PTQNMPMGPGGMNQSGPPPPPRSHNMPSDGMVGGGPPAPHMQNQ---MNGQMPGPNHMPM 135

Query: 126 QGPPQQGGHQQGPPPPPPGKPQGPPPQGGRPQGPPQGQS 164
           QGP     +        P    G    GG     P  QS
Sbjct: 136 QGPGPNQLNMTNSSMNMPSSSHG--SMGGYNHSVPSSQS 172



 Score = 32.0 bits (71), Expect = 0.25
 Identities = 19/44 (43%), Positives = 22/44 (50%), Gaps = 5/44 (11%)

Query: 118 PRPP-RGRPQGPPQQGGHQQGPPPPPPGKPQGPPPQGGRPQGPP 160
           P PP +  P GP   G +Q GPPPPP  +    P  G    GPP
Sbjct: 76  PAPPTQNMPMGPG--GMNQSGPPPPP--RSHNMPSDGMVGGGPP 115


>gi|56117844 synovial sarcoma translocation, chromosome 18 isoform 2
           [Homo sapiens]
          Length = 387

 Score = 64.7 bits (156), Expect = 3e-11
 Identities = 56/121 (46%), Positives = 58/121 (47%), Gaps = 23/121 (19%)

Query: 47  QGPPLG-GQQSQPSAGDGNQDDGPQQGPPQQGGQQQQGPPPPQGKP---QGPPQQGGHPP 102
           QGPP G  QQ  P   DGN   G QQ          QGPPP QG P   Q  P Q G+P 
Sbjct: 280 QGPPEGMNQQYYP---DGNSQYGQQQ-------DAYQGPPPQQGYPPQQQQYPGQQGYPG 329

Query: 103 PPQGRPQGPPQQGGHPRPPRGRPQGPPQQGGHQQGPPPPPPGKPQGPPPQGGRPQGPPQG 162
             QG   GP Q G  P+ P   PQG  QQ G   G  P  PG PQ PP Q  RP G  QG
Sbjct: 330 QQQG--YGPSQGGPGPQYP-NYPQGQGQQYG---GYRPTQPGPPQ-PPQQ--RPYGYDQG 380

Query: 163 Q 163
           Q
Sbjct: 381 Q 381



 Score = 61.2 bits (147), Expect = 4e-10
 Identities = 64/179 (35%), Positives = 68/179 (37%), Gaps = 65/179 (36%)

Query: 47  QGPPLGGQQSQPSAGDGNQDDGPQQGP-------------PQQGGQQQQGPPPPQGKPQG 93
           QG P+G    +P     N    P QGP             PQ GGQ  QG  PP G   G
Sbjct: 183 QGQPMGNYGPRP-----NMSMQPNQGPMMHQQPPSQQYNMPQGGGQHYQGQQPPMGM-MG 236

Query: 94  PPQQGGHP------PPPQGRPQGPPQQ-------------GGHPRPPRGR-----PQGPP 129
              QG H       PP +   QGPPQQ              G   PP G      P G  
Sbjct: 237 QVNQGNHMMGQRQIPPYRPPQQGPPQQYSGQEDYYGDQYSHGGQGPPEGMNQQYYPDGNS 296

Query: 130 QQGGHQ---QGPPP----PP-----------PGKPQG-PPPQGG-RPQGP--PQGQSPQ 166
           Q G  Q   QGPPP    PP           PG+ QG  P QGG  PQ P  PQGQ  Q
Sbjct: 297 QYGQQQDAYQGPPPQQGYPPQQQQYPGQQGYPGQQQGYGPSQGGPGPQYPNYPQGQGQQ 355



 Score = 34.7 bits (78), Expect = 0.038
 Identities = 26/71 (36%), Positives = 27/71 (38%), Gaps = 12/71 (16%)

Query: 85  PPPQGKPQGP--PQQGGHPPPPQGR--PQGPPQQGGHPRPPRGRPQGPPQQGGHQQGPPP 140
           PP Q  P GP    Q G PPPP+    P      GG P P         Q  G   GP  
Sbjct: 78  PPTQNMPMGPGGMNQSGPPPPPRSHNMPSDGMVGGGPPAPHMQN-----QMNGQMPGPNH 132

Query: 141 PPPGKPQGPPP 151
            P    QGP P
Sbjct: 133 MP---MQGPGP 140



 Score = 32.7 bits (73), Expect = 0.15
 Identities = 25/67 (37%), Positives = 25/67 (37%), Gaps = 7/67 (10%)

Query: 102 PPPQGRPQGP--PQQGGHPRPPRGRPQGPPQQGGHQQGPPPPPPGKP---QGPPPQGGRP 156
           PP Q  P GP    Q G P PPR      P  G    GPP P        Q P P     
Sbjct: 78  PPTQNMPMGPGGMNQSGPPPPPRS--HNMPSDGMVGGGPPAPHMQNQMNGQMPGPNHMPM 135

Query: 157 QGPPQGQ 163
           QGP   Q
Sbjct: 136 QGPGPNQ 142



 Score = 32.3 bits (72), Expect = 0.19
 Identities = 28/99 (28%), Positives = 31/99 (31%), Gaps = 8/99 (8%)

Query: 69  PQQGPPQQGGQQQQGPPPPQGKPQGPPQQ---GGHPPPPQGRPQGPPQQGGHPRPPRGRP 125
           P Q  P   G   Q  PPP  +    P     GG PP P  + Q     G  P P     
Sbjct: 79  PTQNMPMGPGGMNQSGPPPPPRSHNMPSDGMVGGGPPAPHMQNQ---MNGQMPGPNHMPM 135

Query: 126 QGPPQQGGHQQGPPPPPPGKPQGPPPQGGRPQGPPQGQS 164
           QGP     +        P    G    GG     P  QS
Sbjct: 136 QGPGPNQLNMTNSSMNMPSSSHG--SMGGYNHSVPSSQS 172



 Score = 32.0 bits (71), Expect = 0.25
 Identities = 19/44 (43%), Positives = 22/44 (50%), Gaps = 5/44 (11%)

Query: 118 PRPP-RGRPQGPPQQGGHQQGPPPPPPGKPQGPPPQGGRPQGPP 160
           P PP +  P GP   G +Q GPPPPP  +    P  G    GPP
Sbjct: 76  PAPPTQNMPMGPG--GMNQSGPPPPP--RSHNMPSDGMVGGGPP 115


>gi|42544123 splicing factor 1 isoform 3 [Homo sapiens]
          Length = 548

 Score = 64.7 bits (156), Expect = 3e-11
 Identities = 49/137 (35%), Positives = 55/137 (40%), Gaps = 24/137 (17%)

Query: 52  GGQQSQPSAG-DGNQDDGPQQGPPQ-----------QGGQQQQ----GPPPPQGKPQGPP 95
           G  +S+P  G  G    GP  GP              GG   Q    GPPPP  +P  PP
Sbjct: 372 GPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPP 431

Query: 96  Q-QGGHPPPPQGRPQGPPQQGGHP------RPPRGRPQGPPQQGGHQQGPPPPPPGKPQG 148
             QG HPP   G P      G  P      R  +G+   PP   G    PPPPP G+P  
Sbjct: 432 MNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPP- 490

Query: 149 PPPQGGRPQGPPQGQSP 165
           PPP G  P    Q Q P
Sbjct: 491 PPPSGPLPPWQQQQQQP 507



 Score = 57.0 bits (136), Expect = 7e-09
 Identities = 40/116 (34%), Positives = 44/116 (37%), Gaps = 3/116 (2%)

Query: 29  PLVISDGGDSEQFLDEERQGPPLGGQQSQPSAGDGNQDDGPQQGPPQQGGQQQQGPPPPQ 88
           PL    GG     +     GPP    Q  P   +         GPP    Q     P   
Sbjct: 400 PLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMD-QYLGSTPVGS 458

Query: 89  GKPQGPPQQGGHPPPPQGR-PQGPPQQGGHPRPPRGRPQGPPQQGGHQQGPPPPPP 143
           G  +    +G  PPPP G  P  PP   G P PP   P  PP Q   QQ PPPPPP
Sbjct: 459 GVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPL-PPWQQQQQQPPPPPPP 513



 Score = 53.9 bits (128), Expect = 6e-08
 Identities = 46/150 (30%), Positives = 50/150 (33%), Gaps = 37/150 (24%)

Query: 49  PPLGGQQSQPSAGDGNQDDGPQQGPPQQGGQQQQGPPPPQGKPQGPPQ--------QGGH 100
           PP     S   +     + GP +  P  G     GP  P G P   P          GGH
Sbjct: 353 PPPPSLMSTTQSRPPWMNSGPSESRPYHG-MHGGGPGGPGGGPHSFPHPLPSLTGGHGGH 411

Query: 101 PPPPQGRPQGPPQQGGHPRPPRGRPQGPPQQGGHQQGP---------------------- 138
           P   Q  P GPP     P PP    QGP   G H   P                      
Sbjct: 412 PM--QHNPNGPPPPWMQP-PPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKG 468

Query: 139 --PPPPPG-KPQGPPPQGGRPQGPPQGQSP 165
             PPPP G  P  PPP  G+P  PP G  P
Sbjct: 469 MMPPPPMGMMPPPPPPPSGQPPPPPSGPLP 498


>gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]
          Length = 638

 Score = 64.7 bits (156), Expect = 3e-11
 Identities = 49/137 (35%), Positives = 55/137 (40%), Gaps = 24/137 (17%)

Query: 52  GGQQSQPSAG-DGNQDDGPQQGPPQ-----------QGGQQQQ----GPPPPQGKPQGPP 95
           G  +S+P  G  G    GP  GP              GG   Q    GPPPP  +P  PP
Sbjct: 372 GPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPP 431

Query: 96  Q-QGGHPPPPQGRPQGPPQQGGHP------RPPRGRPQGPPQQGGHQQGPPPPPPGKPQG 148
             QG HPP   G P      G  P      R  +G+   PP   G    PPPPP G+P  
Sbjct: 432 MNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPP- 490

Query: 149 PPPQGGRPQGPPQGQSP 165
           PPP G  P    Q Q P
Sbjct: 491 PPPSGPLPPWQQQQQQP 507



 Score = 57.0 bits (136), Expect = 7e-09
 Identities = 40/116 (34%), Positives = 44/116 (37%), Gaps = 3/116 (2%)

Query: 29  PLVISDGGDSEQFLDEERQGPPLGGQQSQPSAGDGNQDDGPQQGPPQQGGQQQQGPPPPQ 88
           PL    GG     +     GPP    Q  P   +         GPP    Q     P   
Sbjct: 400 PLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMD-QYLGSTPVGS 458

Query: 89  GKPQGPPQQGGHPPPPQGR-PQGPPQQGGHPRPPRGRPQGPPQQGGHQQGPPPPPP 143
           G  +    +G  PPPP G  P  PP   G P PP   P  PP Q   QQ PPPPPP
Sbjct: 459 GVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPL-PPWQQQQQQPPPPPPP 513



 Score = 53.9 bits (128), Expect = 6e-08
 Identities = 46/150 (30%), Positives = 50/150 (33%), Gaps = 37/150 (24%)

Query: 49  PPLGGQQSQPSAGDGNQDDGPQQGPPQQGGQQQQGPPPPQGKPQGPPQ--------QGGH 100
           PP     S   +     + GP +  P  G     GP  P G P   P          GGH
Sbjct: 353 PPPPSLMSTTQSRPPWMNSGPSESRPYHG-MHGGGPGGPGGGPHSFPHPLPSLTGGHGGH 411

Query: 101 PPPPQGRPQGPPQQGGHPRPPRGRPQGPPQQGGHQQGP---------------------- 138
           P   Q  P GPP     P PP    QGP   G H   P                      
Sbjct: 412 PM--QHNPNGPPPPWMQP-PPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKG 468

Query: 139 --PPPPPG-KPQGPPPQGGRPQGPPQGQSP 165
             PPPP G  P  PPP  G+P  PP G  P
Sbjct: 469 MMPPPPMGMMPPPPPPPSGQPPPPPSGPLP 498



 Score = 49.3 bits (116), Expect = 2e-06
 Identities = 46/141 (32%), Positives = 50/141 (35%), Gaps = 38/141 (26%)

Query: 49  PPLGGQQSQPSAGDGNQDDGPQQGP--PQQGGQQQQGPPPPQGKPQG-----PPQQG--- 98
           PP  G    P      Q   P  GP  P Q  QQQ  PPPP           P QQ    
Sbjct: 472 PPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTT 531

Query: 99  -------GHPPPPQGRPQ------GPPQQGGHPR----PPRGRPQGPPQQGGHQQGPPPP 141
                  G  PP Q +        G PQ  G+P     PP  +P  PP        PPPP
Sbjct: 532 TTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPG------APPPP 585

Query: 142 PPGKPQGPPPQGGRPQGPPQG 162
           PP     PPP       PP+G
Sbjct: 586 PP-----PPPGSAGMMIPPRG 601



 Score = 35.0 bits (79), Expect = 0.029
 Identities = 26/85 (30%), Positives = 30/85 (35%), Gaps = 2/85 (2%)

Query: 49  PPLGGQQSQPSAGDG--NQDDGPQQGPPQQGGQQQQGPPPPQGKPQGPPQQGGHPPPPQG 106
           PP   QQ+  +A  G       P   P   G Q    P  P   P  PP   G   PP+G
Sbjct: 542 PPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMIPPRG 601

Query: 107 RPQGPPQQGGHPRPPRGRPQGPPQQ 131
                 +    PRP    P   PQQ
Sbjct: 602 GDGPSHESEDFPRPLVTLPGRQPQQ 626


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.307    0.139    0.442 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,323,200
Number of Sequences: 37866
Number of extensions: 1698355
Number of successful extensions: 44837
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1429
Number of HSP's successfully gapped in prelim test: 1564
Number of HSP's that attempted gapping in prelim test: 7527
Number of HSP's gapped (non-prelim): 15593
length of query: 166
length of database: 18,247,518
effective HSP length: 95
effective length of query: 71
effective length of database: 14,650,248
effective search space: 1040167608
effective search space used: 1040167608
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 58 (26.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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