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Search of human proteins with 154354974
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|154354974 phosphatase and actin regulator 2 isoform 3 [Homo
sapiens]
(634 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|154354974 phosphatase and actin regulator 2 isoform 3 [Homo s... 1258 0.0
gi|154354968 phosphatase and actin regulator 2 isoform 1 [Homo s... 1251 0.0
gi|154354972 phosphatase and actin regulator 2 isoform 4 [Homo s... 814 0.0
gi|154354970 phosphatase and actin regulator 2 isoform 2 [Homo s... 814 0.0
gi|115430209 phosphatase and actin regulator 4 isoform 2 [Homo s... 394 e-109
gi|115430211 phosphatase and actin regulator 4 isoform 1 [Homo s... 394 e-109
gi|54144631 phosphatase and actin regulator 1 [Homo sapiens] 270 4e-72
gi|34304354 phosphatase and actin regulator 3 isoform 2 [Homo sa... 229 6e-60
gi|18087853 phosphatase and actin regulator 3 isoform 1 [Homo sa... 229 6e-60
gi|34304356 phosphatase and actin regulator 3 isoform 3 [Homo sa... 225 8e-59
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 70 5e-12
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 64 4e-10
gi|116284392 mucin 2 precursor [Homo sapiens] 64 6e-10
gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2... 62 1e-09
gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1... 62 1e-09
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 62 2e-09
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 60 5e-09
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 60 5e-09
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 60 5e-09
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 60 5e-09
gi|73808090 zinc finger protein 207 isoform b [Homo sapiens] 60 5e-09
gi|52485606 formin-like 2 [Homo sapiens] 60 6e-09
gi|72256200 B-cell CLL/lymphoma 9 [Homo sapiens] 60 6e-09
gi|28559039 mediator complex subunit 1 [Homo sapiens] 59 1e-08
gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ... 59 2e-08
gi|148612835 zinc finger protein 207 isoform c [Homo sapiens] 58 2e-08
gi|4508017 zinc finger protein 207 isoform a [Homo sapiens] 58 2e-08
gi|238624188 diffuse panbronchiolitis critical region 1 protein ... 57 7e-08
gi|239740773 PREDICTED: similar to diffuse panbronchiolitis crit... 57 7e-08
gi|47132519 Ras association and pleckstrin homology domains 1 is... 57 7e-08
>gi|154354974 phosphatase and actin regulator 2 isoform 3 [Homo
sapiens]
Length = 634
Score = 1258 bits (3256), Expect = 0.0
Identities = 634/634 (100%), Positives = 634/634 (100%)
Query: 1 MDNAVDGLDKASIANSDGPTAGSQTPPFKRKGKLSTIGKIFKPWKWRKKKTSDKFRETSA 60
MDNAVDGLDKASIANSDGPTAGSQTPPFKRKGKLSTIGKIFKPWKWRKKKTSDKFRETSA
Sbjct: 1 MDNAVDGLDKASIANSDGPTAGSQTPPFKRKGKLSTIGKIFKPWKWRKKKTSDKFRETSA 60
Query: 61 VLERKISTRQSREELIRRGVLKELPDQDGDVTVNFENSNGHMIPIGEESTREENVVKSEE 120
VLERKISTRQSREELIRRGVLKELPDQDGDVTVNFENSNGHMIPIGEESTREENVVKSEE
Sbjct: 61 VLERKISTRQSREELIRRGVLKELPDQDGDVTVNFENSNGHMIPIGEESTREENVVKSEE 120
Query: 121 GNGSVSEKTPPLEEQAEDKKENTENHSETPAAPALPPSAPPKPRPKPKPKKSPVPPKGAT 180
GNGSVSEKTPPLEEQAEDKKENTENHSETPAAPALPPSAPPKPRPKPKPKKSPVPPKGAT
Sbjct: 121 GNGSVSEKTPPLEEQAEDKKENTENHSETPAAPALPPSAPPKPRPKPKPKKSPVPPKGAT 180
Query: 181 AGASHKGDEVPPIKKNTKAPGKQAPVPPPKPASRNTTREAAGSSHSKKTTGSKASASPST 240
AGASHKGDEVPPIKKNTKAPGKQAPVPPPKPASRNTTREAAGSSHSKKTTGSKASASPST
Sbjct: 181 AGASHKGDEVPPIKKNTKAPGKQAPVPPPKPASRNTTREAAGSSHSKKTTGSKASASPST 240
Query: 241 SSTSSRPKASKETVSSKAGTVGTTKGKRKTDKQPITSHLSSDTTTSGTSDLKGEPAETRV 300
SSTSSRPKASKETVSSKAGTVGTTKGKRKTDKQPITSHLSSDTTTSGTSDLKGEPAETRV
Sbjct: 241 SSTSSRPKASKETVSSKAGTVGTTKGKRKTDKQPITSHLSSDTTTSGTSDLKGEPAETRV 300
Query: 301 ESFKLEQTVPGAEEQNTGKFKSMVPPPPVAPAPSPLAPPLPLEDQCITASDTPVVLVSVG 360
ESFKLEQTVPGAEEQNTGKFKSMVPPPPVAPAPSPLAPPLPLEDQCITASDTPVVLVSVG
Sbjct: 301 ESFKLEQTVPGAEEQNTGKFKSMVPPPPVAPAPSPLAPPLPLEDQCITASDTPVVLVSVG 360
Query: 361 ADLPVSALDPSQLLWAEEPTNRTTLYSGTGLSVNRENAKCFTTKEELGKTVPQLLTPGLM 420
ADLPVSALDPSQLLWAEEPTNRTTLYSGTGLSVNRENAKCFTTKEELGKTVPQLLTPGLM
Sbjct: 361 ADLPVSALDPSQLLWAEEPTNRTTLYSGTGLSVNRENAKCFTTKEELGKTVPQLLTPGLM 420
Query: 421 GESSESFSASEDEGHREYQANDSDSDGPILYTDDEDEDEDEDGSGESALASKIRRRDTLA 480
GESSESFSASEDEGHREYQANDSDSDGPILYTDDEDEDEDEDGSGESALASKIRRRDTLA
Sbjct: 421 GESSESFSASEDEGHREYQANDSDSDGPILYTDDEDEDEDEDGSGESALASKIRRRDTLA 480
Query: 481 IKLGNRPSKKELEDKNILQRTSEEERQEIRQQIGTKLVRRLSQRPTTEELEQRNILKQKN 540
IKLGNRPSKKELEDKNILQRTSEEERQEIRQQIGTKLVRRLSQRPTTEELEQRNILKQKN
Sbjct: 481 IKLGNRPSKKELEDKNILQRTSEEERQEIRQQIGTKLVRRLSQRPTTEELEQRNILKQKN 540
Query: 541 EEEEQEAKMELKRRLSRKLSLRPTVAELQARRILRFNEYVEVTDSPDYDRRADKPWARLT 600
EEEEQEAKMELKRRLSRKLSLRPTVAELQARRILRFNEYVEVTDSPDYDRRADKPWARLT
Sbjct: 541 EEEEQEAKMELKRRLSRKLSLRPTVAELQARRILRFNEYVEVTDSPDYDRRADKPWARLT 600
Query: 601 PADKAAIRKELNEFKSTEMEVHEESRQFTRFHRP 634
PADKAAIRKELNEFKSTEMEVHEESRQFTRFHRP
Sbjct: 601 PADKAAIRKELNEFKSTEMEVHEESRQFTRFHRP 634
>gi|154354968 phosphatase and actin regulator 2 isoform 1 [Homo
sapiens]
Length = 645
Score = 1251 bits (3236), Expect = 0.0
Identities = 630/631 (99%), Positives = 631/631 (100%)
Query: 4 AVDGLDKASIANSDGPTAGSQTPPFKRKGKLSTIGKIFKPWKWRKKKTSDKFRETSAVLE 63
+VDGLDKASIANSDGPTAGSQTPPFKRKGKLSTIGKIFKPWKWRKKKTSDKFRETSAVLE
Sbjct: 15 SVDGLDKASIANSDGPTAGSQTPPFKRKGKLSTIGKIFKPWKWRKKKTSDKFRETSAVLE 74
Query: 64 RKISTRQSREELIRRGVLKELPDQDGDVTVNFENSNGHMIPIGEESTREENVVKSEEGNG 123
RKISTRQSREELIRRGVLKELPDQDGDVTVNFENSNGHMIPIGEESTREENVVKSEEGNG
Sbjct: 75 RKISTRQSREELIRRGVLKELPDQDGDVTVNFENSNGHMIPIGEESTREENVVKSEEGNG 134
Query: 124 SVSEKTPPLEEQAEDKKENTENHSETPAAPALPPSAPPKPRPKPKPKKSPVPPKGATAGA 183
SVSEKTPPLEEQAEDKKENTENHSETPAAPALPPSAPPKPRPKPKPKKSPVPPKGATAGA
Sbjct: 135 SVSEKTPPLEEQAEDKKENTENHSETPAAPALPPSAPPKPRPKPKPKKSPVPPKGATAGA 194
Query: 184 SHKGDEVPPIKKNTKAPGKQAPVPPPKPASRNTTREAAGSSHSKKTTGSKASASPSTSST 243
SHKGDEVPPIKKNTKAPGKQAPVPPPKPASRNTTREAAGSSHSKKTTGSKASASPSTSST
Sbjct: 195 SHKGDEVPPIKKNTKAPGKQAPVPPPKPASRNTTREAAGSSHSKKTTGSKASASPSTSST 254
Query: 244 SSRPKASKETVSSKAGTVGTTKGKRKTDKQPITSHLSSDTTTSGTSDLKGEPAETRVESF 303
SSRPKASKETVSSKAGTVGTTKGKRKTDKQPITSHLSSDTTTSGTSDLKGEPAETRVESF
Sbjct: 255 SSRPKASKETVSSKAGTVGTTKGKRKTDKQPITSHLSSDTTTSGTSDLKGEPAETRVESF 314
Query: 304 KLEQTVPGAEEQNTGKFKSMVPPPPVAPAPSPLAPPLPLEDQCITASDTPVVLVSVGADL 363
KLEQTVPGAEEQNTGKFKSMVPPPPVAPAPSPLAPPLPLEDQCITASDTPVVLVSVGADL
Sbjct: 315 KLEQTVPGAEEQNTGKFKSMVPPPPVAPAPSPLAPPLPLEDQCITASDTPVVLVSVGADL 374
Query: 364 PVSALDPSQLLWAEEPTNRTTLYSGTGLSVNRENAKCFTTKEELGKTVPQLLTPGLMGES 423
PVSALDPSQLLWAEEPTNRTTLYSGTGLSVNRENAKCFTTKEELGKTVPQLLTPGLMGES
Sbjct: 375 PVSALDPSQLLWAEEPTNRTTLYSGTGLSVNRENAKCFTTKEELGKTVPQLLTPGLMGES 434
Query: 424 SESFSASEDEGHREYQANDSDSDGPILYTDDEDEDEDEDGSGESALASKIRRRDTLAIKL 483
SESFSASEDEGHREYQANDSDSDGPILYTDDEDEDEDEDGSGESALASKIRRRDTLAIKL
Sbjct: 435 SESFSASEDEGHREYQANDSDSDGPILYTDDEDEDEDEDGSGESALASKIRRRDTLAIKL 494
Query: 484 GNRPSKKELEDKNILQRTSEEERQEIRQQIGTKLVRRLSQRPTTEELEQRNILKQKNEEE 543
GNRPSKKELEDKNILQRTSEEERQEIRQQIGTKLVRRLSQRPTTEELEQRNILKQKNEEE
Sbjct: 495 GNRPSKKELEDKNILQRTSEEERQEIRQQIGTKLVRRLSQRPTTEELEQRNILKQKNEEE 554
Query: 544 EQEAKMELKRRLSRKLSLRPTVAELQARRILRFNEYVEVTDSPDYDRRADKPWARLTPAD 603
EQEAKMELKRRLSRKLSLRPTVAELQARRILRFNEYVEVTDSPDYDRRADKPWARLTPAD
Sbjct: 555 EQEAKMELKRRLSRKLSLRPTVAELQARRILRFNEYVEVTDSPDYDRRADKPWARLTPAD 614
Query: 604 KAAIRKELNEFKSTEMEVHEESRQFTRFHRP 634
KAAIRKELNEFKSTEMEVHEESRQFTRFHRP
Sbjct: 615 KAAIRKELNEFKSTEMEVHEESRQFTRFHRP 645
>gi|154354972 phosphatase and actin regulator 2 isoform 4 [Homo
sapiens]
Length = 554
Score = 814 bits (2102), Expect = 0.0
Identities = 415/424 (97%), Positives = 416/424 (98%)
Query: 211 PASRNTTREAAGSSHSKKTTGSKASASPSTSSTSSRPKASKETVSSKAGTVGTTKGKRKT 270
P + AGSSHSKKTTGSKASASPSTSSTSSRPKASKETVSSKAGTVGTTKGKRKT
Sbjct: 131 PLEEQAEDKKAGSSHSKKTTGSKASASPSTSSTSSRPKASKETVSSKAGTVGTTKGKRKT 190
Query: 271 DKQPITSHLSSDTTTSGTSDLKGEPAETRVESFKLEQTVPGAEEQNTGKFKSMVPPPPVA 330
DKQPITSHLSSDTTTSGTSDLKGEPAETRVESFKLEQTVPGAEEQNTGKFKSMVPPPPVA
Sbjct: 191 DKQPITSHLSSDTTTSGTSDLKGEPAETRVESFKLEQTVPGAEEQNTGKFKSMVPPPPVA 250
Query: 331 PAPSPLAPPLPLEDQCITASDTPVVLVSVGADLPVSALDPSQLLWAEEPTNRTTLYSGTG 390
PAPSPLAPPLPLEDQCITASDTPVVLVSVGADLPVSALDPSQLLWAEEPTNRTTLYSGTG
Sbjct: 251 PAPSPLAPPLPLEDQCITASDTPVVLVSVGADLPVSALDPSQLLWAEEPTNRTTLYSGTG 310
Query: 391 LSVNRENAKCFTTKEELGKTVPQLLTPGLMGESSESFSASEDEGHREYQANDSDSDGPIL 450
LSVNRENAKCFTTKEELGKTVPQLLTPGLMGESSESFSASEDEGHREYQANDSDSDGPIL
Sbjct: 311 LSVNRENAKCFTTKEELGKTVPQLLTPGLMGESSESFSASEDEGHREYQANDSDSDGPIL 370
Query: 451 YTDDEDEDEDEDGSGESALASKIRRRDTLAIKLGNRPSKKELEDKNILQRTSEEERQEIR 510
YTDDEDEDEDEDGSGESALASKIRRRDTLAIKLGNRPSKKELEDKNILQRTSEEERQEIR
Sbjct: 371 YTDDEDEDEDEDGSGESALASKIRRRDTLAIKLGNRPSKKELEDKNILQRTSEEERQEIR 430
Query: 511 QQIGTKLVRRLSQRPTTEELEQRNILKQKNEEEEQEAKMELKRRLSRKLSLRPTVAELQA 570
QQIGTKLVRRLSQRPTTEELEQRNILKQKNEEEEQEAKMELKRRLSRKLSLRPTVAELQA
Sbjct: 431 QQIGTKLVRRLSQRPTTEELEQRNILKQKNEEEEQEAKMELKRRLSRKLSLRPTVAELQA 490
Query: 571 RRILRFNEYVEVTDSPDYDRRADKPWARLTPADKAAIRKELNEFKSTEMEVHEESRQFTR 630
RRILRFNEYVEVTDSPDYDRRADKPWARLTPADKAAIRKELNEFKSTEMEVHEESRQFTR
Sbjct: 491 RRILRFNEYVEVTDSPDYDRRADKPWARLTPADKAAIRKELNEFKSTEMEVHEESRQFTR 550
Query: 631 FHRP 634
FHRP
Sbjct: 551 FHRP 554
Score = 296 bits (758), Expect = 4e-80
Identities = 152/194 (78%), Positives = 160/194 (82%), Gaps = 3/194 (1%)
Query: 1 MDNAVDGLDKASIANSDGPTAGSQTPPFKRKGKLSTIGKIFKPWKWRKKKTSDKFRETSA 60
MDNAVDGLDKASIANSDGPTAGSQTPPFKRKGKLSTIGKIFKPWKWRKKKTSDKFRETSA
Sbjct: 1 MDNAVDGLDKASIANSDGPTAGSQTPPFKRKGKLSTIGKIFKPWKWRKKKTSDKFRETSA 60
Query: 61 VLERKISTRQSREELIRRGVLKELPDQDGDVTVNFENSNGHMIPIGEESTREENVVKSEE 120
VLERKISTRQSREELIRRGVLKELPDQDGDVTVNFENSNGHMIPIGEESTREENVVKSEE
Sbjct: 61 VLERKISTRQSREELIRRGVLKELPDQDGDVTVNFENSNGHMIPIGEESTREENVVKSEE 120
Query: 121 GNGSVSEKTPPLEEQAEDKKENTENHSETPAAPALPPSAPPKPRPKPKPKKSPVPPKGAT 180
GNGSVSEKTPPLEEQAEDKK + + +T + A + +PK K V K T
Sbjct: 121 GNGSVSEKTPPLEEQAEDKKAGSSHSKKTTGSKASASPSTSSTSSRPKASKETVSSKAGT 180
Query: 181 AGAS---HKGDEVP 191
G + K D+ P
Sbjct: 181 VGTTKGKRKTDKQP 194
>gi|154354970 phosphatase and actin regulator 2 isoform 2 [Homo
sapiens]
Length = 565
Score = 814 bits (2102), Expect = 0.0
Identities = 415/424 (97%), Positives = 416/424 (98%)
Query: 211 PASRNTTREAAGSSHSKKTTGSKASASPSTSSTSSRPKASKETVSSKAGTVGTTKGKRKT 270
P + AGSSHSKKTTGSKASASPSTSSTSSRPKASKETVSSKAGTVGTTKGKRKT
Sbjct: 142 PLEEQAEDKKAGSSHSKKTTGSKASASPSTSSTSSRPKASKETVSSKAGTVGTTKGKRKT 201
Query: 271 DKQPITSHLSSDTTTSGTSDLKGEPAETRVESFKLEQTVPGAEEQNTGKFKSMVPPPPVA 330
DKQPITSHLSSDTTTSGTSDLKGEPAETRVESFKLEQTVPGAEEQNTGKFKSMVPPPPVA
Sbjct: 202 DKQPITSHLSSDTTTSGTSDLKGEPAETRVESFKLEQTVPGAEEQNTGKFKSMVPPPPVA 261
Query: 331 PAPSPLAPPLPLEDQCITASDTPVVLVSVGADLPVSALDPSQLLWAEEPTNRTTLYSGTG 390
PAPSPLAPPLPLEDQCITASDTPVVLVSVGADLPVSALDPSQLLWAEEPTNRTTLYSGTG
Sbjct: 262 PAPSPLAPPLPLEDQCITASDTPVVLVSVGADLPVSALDPSQLLWAEEPTNRTTLYSGTG 321
Query: 391 LSVNRENAKCFTTKEELGKTVPQLLTPGLMGESSESFSASEDEGHREYQANDSDSDGPIL 450
LSVNRENAKCFTTKEELGKTVPQLLTPGLMGESSESFSASEDEGHREYQANDSDSDGPIL
Sbjct: 322 LSVNRENAKCFTTKEELGKTVPQLLTPGLMGESSESFSASEDEGHREYQANDSDSDGPIL 381
Query: 451 YTDDEDEDEDEDGSGESALASKIRRRDTLAIKLGNRPSKKELEDKNILQRTSEEERQEIR 510
YTDDEDEDEDEDGSGESALASKIRRRDTLAIKLGNRPSKKELEDKNILQRTSEEERQEIR
Sbjct: 382 YTDDEDEDEDEDGSGESALASKIRRRDTLAIKLGNRPSKKELEDKNILQRTSEEERQEIR 441
Query: 511 QQIGTKLVRRLSQRPTTEELEQRNILKQKNEEEEQEAKMELKRRLSRKLSLRPTVAELQA 570
QQIGTKLVRRLSQRPTTEELEQRNILKQKNEEEEQEAKMELKRRLSRKLSLRPTVAELQA
Sbjct: 442 QQIGTKLVRRLSQRPTTEELEQRNILKQKNEEEEQEAKMELKRRLSRKLSLRPTVAELQA 501
Query: 571 RRILRFNEYVEVTDSPDYDRRADKPWARLTPADKAAIRKELNEFKSTEMEVHEESRQFTR 630
RRILRFNEYVEVTDSPDYDRRADKPWARLTPADKAAIRKELNEFKSTEMEVHEESRQFTR
Sbjct: 502 RRILRFNEYVEVTDSPDYDRRADKPWARLTPADKAAIRKELNEFKSTEMEVHEESRQFTR 561
Query: 631 FHRP 634
FHRP
Sbjct: 562 FHRP 565
Score = 288 bits (738), Expect = 8e-78
Identities = 148/191 (77%), Positives = 157/191 (82%), Gaps = 3/191 (1%)
Query: 4 AVDGLDKASIANSDGPTAGSQTPPFKRKGKLSTIGKIFKPWKWRKKKTSDKFRETSAVLE 63
+VDGLDKASIANSDGPTAGSQTPPFKRKGKLSTIGKIFKPWKWRKKKTSDKFRETSAVLE
Sbjct: 15 SVDGLDKASIANSDGPTAGSQTPPFKRKGKLSTIGKIFKPWKWRKKKTSDKFRETSAVLE 74
Query: 64 RKISTRQSREELIRRGVLKELPDQDGDVTVNFENSNGHMIPIGEESTREENVVKSEEGNG 123
RKISTRQSREELIRRGVLKELPDQDGDVTVNFENSNGHMIPIGEESTREENVVKSEEGNG
Sbjct: 75 RKISTRQSREELIRRGVLKELPDQDGDVTVNFENSNGHMIPIGEESTREENVVKSEEGNG 134
Query: 124 SVSEKTPPLEEQAEDKKENTENHSETPAAPALPPSAPPKPRPKPKPKKSPVPPKGATAGA 183
SVSEKTPPLEEQAEDKK + + +T + A + +PK K V K T G
Sbjct: 135 SVSEKTPPLEEQAEDKKAGSSHSKKTTGSKASASPSTSSTSSRPKASKETVSSKAGTVGT 194
Query: 184 S---HKGDEVP 191
+ K D+ P
Sbjct: 195 TKGKRKTDKQP 205
>gi|115430209 phosphatase and actin regulator 4 isoform 2 [Homo
sapiens]
Length = 712
Score = 394 bits (1012), Expect = e-109
Identities = 281/700 (40%), Positives = 361/700 (51%), Gaps = 99/700 (14%)
Query: 17 DGPTAGSQTPPFKRKGKLSTIGKIFKPWKWRKKKTSDKFRETSAVLERKISTRQSREELI 76
D AG TPP KRK K S GKIFKPWKWRKKK+SDKF+ETS VLERKIS R+ REEL+
Sbjct: 30 DSVEAGDTTPPTKRKSKFSGFGKIFKPWKWRKKKSSDKFKETSEVLERKISMRKPREELV 89
Query: 77 RRGVLKELPDQDGDVTVNFENS---NGHMIPIG-----------EESTR---------EE 113
+RGVL E P+Q G+ ++ NGH PIG EE R EE
Sbjct: 90 KRGVLLEDPEQGGEDPGKPSDAMLKNGHTTPIGNARSSSPVQVEEEPVRLASLRKAIPEE 149
Query: 114 NVVKSEEGNGS--------VSEKTP---------PL-------EEQAEDKKEN------- 142
++ K GS V E P PL E QA+D +
Sbjct: 150 DLKKRLGSTGSQPNSEAESVPENVPKPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFI 209
Query: 143 -----TENHSETPAAPALPPSAPPKPRPKPKPKKSPVPPKGATAGASHKGDEVPPIKKNT 197
T + T AA +L + P P P+ P P A+ +
Sbjct: 210 ISTSITTAPAATTAATSLAKTVNLSVTPSPAPRTLPAAPASTNTTATPSLTHM------- 262
Query: 198 KAPGKQAPVPPPKPASRNTTREAAGSSHSKKTTGSKASASPSTSSTSSRPKASKETVSSK 257
P KQ P+PPPKPA RN+ A S + + + SP P S T+ S
Sbjct: 263 -VPAKQPPIPPPKPAHRNSNPVIAELSQAINSGTLLSKPSPPLPPKRGIPSTSVPTLESA 321
Query: 258 AG-TVGTTKGKR-----------------KTDKQPITSHLSSDTTTSGTSDLKGEPAETR 299
A T T +R ++ P+ +H+ + + K
Sbjct: 322 AAITTKTPSDEREKSTCSMGSELLPMISPRSPSPPLPTHIPPEPPRTPPFPAKTFQVVPE 381
Query: 300 VE---SFKLEQTVPGAEEQNTGKFKSMVPPPPVAPAPSPLAPPLPLEDQCITASDTPVVL 356
+E S L Q +P E+Q K ++ P PPLPL + A +P+ +
Sbjct: 382 IEFPPSLDLHQEIPQQEDQKKEVPKRILDQNFGEPHIPSRLPPLPLHIRIQQALTSPLPM 441
Query: 357 VSV--GADLPVSALDPSQLLWAEEPTNRTTLYSGTGLSVNRENAKCFTTKEELGKTVPQL 414
+ G+ S L + ++E+ + TL L + E K +EE +T P
Sbjct: 442 TPILEGSHRAHSLLFENSDSFSEDSS---TLGRTRSLPITIEMLKVPDDEEEEEQTCPST 498
Query: 415 LTPGLMGESSESFSASEDEGHREYQANDSDSDGPILYTDDEDEDEDEDGSGESALASKIR 474
+ M +S + E + +DSDS+GPI Y D+EDEDE S +SALA+K++
Sbjct: 499 FSEE-MTPTSVIPKLPQCLREEEEKESDSDSEGPIQYRDEEDEDE----SYQSALANKVK 553
Query: 475 RRDTLAIKLGNRPSKKELEDKNILQRTSEEERQEIRQQIGTKLVRRLSQRPTTEELEQRN 534
R+DTLA+KL +RPS+ EL + N S+EE EIR QIG L+RRLSQRPT EELEQRN
Sbjct: 554 RKDTLAMKLNHRPSEPEL-NLNSWPCKSKEEWNEIRHQIGNTLIRRLSQRPTPEELEQRN 612
Query: 535 ILKQKNEEEEQEAKMELKRRLSRKLSLRPTVAELQARRILRFNEYVEVTDSPDYDRRADK 594
IL+ KNE + Q K E+KRRL+RKLS RPTVAEL AR+ILRFNEYVEVTD+ DYDRRADK
Sbjct: 613 ILQPKNEADRQAEKREIKRRLTRKLSQRPTVAELLARKILRFNEYVEVTDAQDYDRRADK 672
Query: 595 PWARLTPADKAAIRKELNEFKSTEMEVHEESRQFTRFHRP 634
PW +LTPADKAAIRKELNEFKS+EMEVHEES+ FTR+HRP
Sbjct: 673 PWTKLTPADKAAIRKELNEFKSSEMEVHEESKHFTRYHRP 712
>gi|115430211 phosphatase and actin regulator 4 isoform 1 [Homo
sapiens]
Length = 702
Score = 394 bits (1012), Expect = e-109
Identities = 281/700 (40%), Positives = 361/700 (51%), Gaps = 99/700 (14%)
Query: 17 DGPTAGSQTPPFKRKGKLSTIGKIFKPWKWRKKKTSDKFRETSAVLERKISTRQSREELI 76
D AG TPP KRK K S GKIFKPWKWRKKK+SDKF+ETS VLERKIS R+ REEL+
Sbjct: 20 DSVEAGDTTPPTKRKSKFSGFGKIFKPWKWRKKKSSDKFKETSEVLERKISMRKPREELV 79
Query: 77 RRGVLKELPDQDGDVTVNFENS---NGHMIPIG-----------EESTR---------EE 113
+RGVL E P+Q G+ ++ NGH PIG EE R EE
Sbjct: 80 KRGVLLEDPEQGGEDPGKPSDAMLKNGHTTPIGNARSSSPVQVEEEPVRLASLRKAIPEE 139
Query: 114 NVVKSEEGNGS--------VSEKTP---------PL-------EEQAEDKKEN------- 142
++ K GS V E P PL E QA+D +
Sbjct: 140 DLKKRLGSTGSQPNSEAESVPENVPKPPLLPPKRPLSSSHEASEGQAKDATSSGGTARFI 199
Query: 143 -----TENHSETPAAPALPPSAPPKPRPKPKPKKSPVPPKGATAGASHKGDEVPPIKKNT 197
T + T AA +L + P P P+ P P A+ +
Sbjct: 200 ISTSITTAPAATTAATSLAKTVNLSVTPSPAPRTLPAAPASTNTTATPSLTHM------- 252
Query: 198 KAPGKQAPVPPPKPASRNTTREAAGSSHSKKTTGSKASASPSTSSTSSRPKASKETVSSK 257
P KQ P+PPPKPA RN+ A S + + + SP P S T+ S
Sbjct: 253 -VPAKQPPIPPPKPAHRNSNPVIAELSQAINSGTLLSKPSPPLPPKRGIPSTSVPTLESA 311
Query: 258 AG-TVGTTKGKR-----------------KTDKQPITSHLSSDTTTSGTSDLKGEPAETR 299
A T T +R ++ P+ +H+ + + K
Sbjct: 312 AAITTKTPSDEREKSTCSMGSELLPMISPRSPSPPLPTHIPPEPPRTPPFPAKTFQVVPE 371
Query: 300 VE---SFKLEQTVPGAEEQNTGKFKSMVPPPPVAPAPSPLAPPLPLEDQCITASDTPVVL 356
+E S L Q +P E+Q K ++ P PPLPL + A +P+ +
Sbjct: 372 IEFPPSLDLHQEIPQQEDQKKEVPKRILDQNFGEPHIPSRLPPLPLHIRIQQALTSPLPM 431
Query: 357 VSV--GADLPVSALDPSQLLWAEEPTNRTTLYSGTGLSVNRENAKCFTTKEELGKTVPQL 414
+ G+ S L + ++E+ + TL L + E K +EE +T P
Sbjct: 432 TPILEGSHRAHSLLFENSDSFSEDSS---TLGRTRSLPITIEMLKVPDDEEEEEQTCPST 488
Query: 415 LTPGLMGESSESFSASEDEGHREYQANDSDSDGPILYTDDEDEDEDEDGSGESALASKIR 474
+ M +S + E + +DSDS+GPI Y D+EDEDE S +SALA+K++
Sbjct: 489 FSEE-MTPTSVIPKLPQCLREEEEKESDSDSEGPIQYRDEEDEDE----SYQSALANKVK 543
Query: 475 RRDTLAIKLGNRPSKKELEDKNILQRTSEEERQEIRQQIGTKLVRRLSQRPTTEELEQRN 534
R+DTLA+KL +RPS+ EL + N S+EE EIR QIG L+RRLSQRPT EELEQRN
Sbjct: 544 RKDTLAMKLNHRPSEPEL-NLNSWPCKSKEEWNEIRHQIGNTLIRRLSQRPTPEELEQRN 602
Query: 535 ILKQKNEEEEQEAKMELKRRLSRKLSLRPTVAELQARRILRFNEYVEVTDSPDYDRRADK 594
IL+ KNE + Q K E+KRRL+RKLS RPTVAEL AR+ILRFNEYVEVTD+ DYDRRADK
Sbjct: 603 ILQPKNEADRQAEKREIKRRLTRKLSQRPTVAELLARKILRFNEYVEVTDAQDYDRRADK 662
Query: 595 PWARLTPADKAAIRKELNEFKSTEMEVHEESRQFTRFHRP 634
PW +LTPADKAAIRKELNEFKS+EMEVHEES+ FTR+HRP
Sbjct: 663 PWTKLTPADKAAIRKELNEFKSSEMEVHEESKHFTRYHRP 702
>gi|54144631 phosphatase and actin regulator 1 [Homo sapiens]
Length = 580
Score = 270 bits (689), Expect = 4e-72
Identities = 144/210 (68%), Positives = 171/210 (81%), Gaps = 6/210 (2%)
Query: 431 EDEGHREYQANDSD-SDGPILYT---DDEDEDEDEDGS-GESALASKIRRRDTLAIKLGN 485
E + ++E ++SD D LYT ++E+EDED+D S S+LA K+ R+D+LAIKL N
Sbjct: 371 ECDDNKENVPHESDYEDSSCLYTREEEEEEEDEDDDSSLYTSSLAMKVCRKDSLAIKLSN 430
Query: 486 RPSKKELEDKNILQRTSEEERQEIRQQIGTKLVRRLSQRPTTEELEQRNILKQKNEEEEQ 545
RPSK+ELE+KNIL R ++EER E+RQQIGTKL RRLSQRPT EELEQRNILK +NE+EEQ
Sbjct: 431 RPSKRELEEKNILPRQTDEERLELRQQIGTKLTRRLSQRPTAEELEQRNILKPRNEQEEQ 490
Query: 546 EAKMELKRRLSRKLSLRPTVAELQARRIL-RFNEYVEVTDSPDYDRRADKPWARLTPADK 604
E K E+KRRL+RKLS RPTV EL+ R+IL RF++YVEV D+ DYDRRADKPW RLT ADK
Sbjct: 491 EEKREIKRRLTRKLSQRPTVEELRERKILIRFSDYVEVADAQDYDRRADKPWTRLTAADK 550
Query: 605 AAIRKELNEFKSTEMEVHEESRQFTRFHRP 634
AAIRKELNEFKSTEMEVHE SR TRFHRP
Sbjct: 551 AAIRKELNEFKSTEMEVHELSRHLTRFHRP 580
Score = 117 bits (294), Expect = 2e-26
Identities = 147/559 (26%), Positives = 234/559 (41%), Gaps = 70/559 (12%)
Query: 4 AVDGLDKASIANSDGPTAGSQTPPFKRKGKLSTIGKIFKPWKWRKKKTSDKFRETSAVLE 63
A + +++ + SD G+ TPP +R+ K + +G+IFKPWKWRKKK S+KF+ TSA LE
Sbjct: 83 AAEEVERLAAMRSDSLVPGTHTPPIRRRSKFANLGRIFKPWKWRKKK-SEKFKHTSAALE 141
Query: 64 RKISTRQSREELIRRGVLKELPDQDGDVTVNFENSNGHMIPIGEESTREENVVKSEEGNG 123
RKIS RQSREELI+RGVLKE+ D+DG+++++ E E+S + S + +
Sbjct: 142 RKISMRQSREELIKRGVLKEIYDKDGELSISNE----------EDSLENGQSLSSSQLSL 191
Query: 124 SVSEKTPPLEEQAEDKKENTENHSETPAAPALPPSAPPKPRPKPKPKKSPVPPKGATAGA 183
+ P+ + S+ P P AP K P P+PPK
Sbjct: 192 PALSEMEPVPMPRDPCSYEVLQPSDIMDGP--DPGAPVKLPCLPVKLSPPLPPKKVMICM 249
Query: 184 SHKGDEVPPIKKNTKAPGKQAPVPPPKPASRNTTREAAGSSHSKKTTGSKASASPSTSST 243
G ++ + + G+Q A + T + H + GS PST+ +
Sbjct: 250 PVGGPDLSLVSYTAQKSGQQG------VAQHHHTVLPSQIQHQLQ-YGSHGQHLPSTTGS 302
Query: 244 SSRPKASKETVSSKAGTVGTTKGKRKTDKQ--PITSHLSSDTTTSGTSDLKGEPAETRVE 301
+ + T+ T + ++ +Q P ++ S SG K P +
Sbjct: 303 LPMHPSGCRMIDELNKTLAMTMQRLESSEQRVPCSTSYHSSGLHSGDGVTKAGP--MGLP 360
Query: 302 SFKLEQTVPGAEEQNTGKFKSMVPPPPVAPAPSPLAPPLPLEDQCITASDTPVVLVSVGA 361
+ TV + N K VP S L E++ D+ + S+
Sbjct: 361 EIRQVPTVVIECDDN----KENVPHESDYEDSSCLYTREEEEEEEDEDDDSSLYTSSLA- 415
Query: 362 DLPVSALDPSQLLWAEEPTNRTTLYSGTGLSVNRENAKCFTTKEELGKTVPQLLTPGLMG 421
+ V D + + P+ R + +N T EE + Q+ T L
Sbjct: 416 -MKVCRKDSLAIKLSNRPSKR---------ELEEKNILPRQTDEERLELRQQIGTK-LTR 464
Query: 422 ESSESFSASEDEGHREYQANDSDSDGPILYTDDEDEDEDEDGSGESALASKIRRRDTLAI 481
S+ +A E E Q N IL +E E+++E +I+RR L
Sbjct: 465 RLSQRPTAEELE-----QRN-------ILKPRNEQEEQEE--------KREIKRR--LTR 502
Query: 482 KLGNRPSKKELEDKNILQRTSEEERQEIRQQIGTKLVRRLSQRPTTE--ELEQRNILKQK 539
KL RP+ +EL ++ IL R S+ Q R + +P T ++ I K+
Sbjct: 503 KLSQRPTVEELRERKILIRFSDYVEVADAQDYD-----RRADKPWTRLTAADKAAIRKEL 557
Query: 540 NEEEEQEAKM-ELKRRLSR 557
NE + E ++ EL R L+R
Sbjct: 558 NEFKSTEMEVHELSRHLTR 576
Score = 33.1 bits (74), Expect = 0.80
Identities = 45/170 (26%), Positives = 70/170 (41%), Gaps = 26/170 (15%)
Query: 414 LLTPGLMGESSESFSASEDEGHREYQANDSDSDGPILYTDDEDEDEDEDGSGESALASKI 473
LL P LM SSE +D R + S SD P L E G+ E
Sbjct: 41 LLPPTLMAASSE-----DDIDRRPIRRVRSKSDTPYLA---EARISFNLGAAEEVERLAA 92
Query: 474 RRRDTLAIKLGNRPSKKELEDKNILQRTS----EEERQEIRQQIGTKLVRRLSQRPTTEE 529
R D+L P ++ + N+ + +++ E + L R++S R + EE
Sbjct: 93 MRSDSLVPGTHTPPIRRRSKFANLGRIFKPWKWRKKKSEKFKHTSAALERKISMRQSREE 152
Query: 530 LEQRNILKQ----------KNEEEEQEAKMELKRRLSRKLSLRPTVAELQ 569
L +R +LK+ NEE+ E L S +LSL P ++E++
Sbjct: 153 LIKRGVLKEIYDKDGELSISNEEDSLENGQSLS---SSQLSL-PALSEME 198
>gi|34304354 phosphatase and actin regulator 3 isoform 2 [Homo
sapiens]
Length = 518
Score = 229 bits (584), Expect = 6e-60
Identities = 164/436 (37%), Positives = 225/436 (51%), Gaps = 24/436 (5%)
Query: 208 PPKPASRNTTREAAGSSHSKKTTGSKASASPSTSSTSSRPKASKETVSSKAGTVGTTKGK 267
PP P S T E A T + S SS + A+K +S
Sbjct: 98 PPTPKSETLTSEDAQPGSPLATGTDQVSLDKPLSSAAHLDDAAKMPSASSGEEADAGS-- 155
Query: 268 RKTDKQPITSHLSSDTTTSGTSDLKGEPAETRVESFKLEQTVPGAEEQNTGKF-KSMVPP 326
P T+ LS + + D P E V +P + + K K++
Sbjct: 156 ----LLPTTNELSQALAGADSLDSPPRPLERSVGQLPSPPLLPTPPPKASSKTTKNVTGQ 211
Query: 327 PPVAPAPSPLAPPLPLEDQCITASDTPVVLVSVGADLPVSALDPSQLLWAEEPTNRTTLY 386
+ A S + L Q T + +P L +V LP S + +L A +R +
Sbjct: 212 ATLFQASSMKSADPSLRGQLSTPTGSPH-LTTVHRPLPPSRVI-EELHRALATKHRQDSF 269
Query: 387 SGT---GLSVNRENAKCFTTKE-ELGKTVPQLLTPGLMGESSESFSASEDEGHREYQAND 442
G G R + + T E GK + + E+ + + +E N
Sbjct: 270 QGRESKGSPKKRLDVRLSRTSSVERGKEREEAWSFDGALENKRTAAKESEENKENLIINS 329
Query: 443 SDSDGPILYTDDEDEDEDEDGSGESALASKIRRR---DTLAIKLGNRPSKKELEDKNILQ 499
D +LY +DE+ +S ++ + R+ + LA+KL NRPSK+ELED+NI
Sbjct: 330 ELKDDLLLY-------QDEEALNDSIISGTLPRKCKKELLAVKLRNRPSKQELEDRNIFP 382
Query: 500 RTSEEERQEIRQQIGTKLVRRLSQRPTTEELEQRNILKQKNEEEEQEAKMELKRRLSRKL 559
R ++EERQEIRQQI KL +RLSQRP EELE+RNILKQ+N++ EQE + E+K+RL+RKL
Sbjct: 383 RRTDEERQEIRQQIEMKLSKRLSQRPAVEELERRNILKQRNDQTEQEERREIKQRLTRKL 442
Query: 560 SLRPTVAELQARRIL-RFNEYVEVTDSPDYDRRADKPWARLTPADKAAIRKELNEFKSTE 618
+ RPTV EL+ R+IL RF++YVEV + DYDRRADKPW RL+ ADKAAIRKELNE+KS E
Sbjct: 443 NQRPTVDELRDRKILIRFSDYVEVAKAQDYDRRADKPWTRLSAADKAAIRKELNEYKSNE 502
Query: 619 MEVHEESRQFTRFHRP 634
MEVH S+ TRFHRP
Sbjct: 503 MEVHASSKHLTRFHRP 518
Score = 97.4 bits (241), Expect = 3e-20
Identities = 75/245 (30%), Positives = 120/245 (48%), Gaps = 10/245 (4%)
Query: 8 LDKASIANSDGPTAGSQTPPFKRKGKLSTIGKIFKPWKWRKKKTSDKFRETSAVLERKIS 67
+D+ A + +G +TPP +R KL+T+G+IFKPWKWRKKK ++K ++T++ LE+K++
Sbjct: 1 MDQTPPARPEYLVSGIRTPPVRRNSKLATLGRIFKPWKWRKKK-NEKLKQTTSALEKKMA 59
Query: 68 TRQSREELIRRGVLKELPDQDGDVTVNFENSNGHMIPIGEESTREENVVKSEEGNGSVSE 127
RQ REELI++G+L E+ +QD + + G E T + + SE+ S
Sbjct: 60 GRQGREELIKKGLL-EMMEQDAE-SKTCNPDGGPRSVQSEPPTPKSETLTSEDAQPG-SP 116
Query: 128 KTPPLEEQAEDKKENTENHSETPAAPALPPSAPPKPRPKPKPKKSPVPPKGATAGASHKG 187
++ + DK ++ H + A S P + + A AGA
Sbjct: 117 LATGTDQVSLDKPLSSAAHLDDAAKMPSASSGEEADAGSLLPTTNEL--SQALAGADSLD 174
Query: 188 DEVPPIKKNT-KAPGKQ-APVPPPKPASRNTTREAAGSSHSKKTTGSKASASPSTSSTSS 245
P++++ + P P PPPK AS TT+ G + + + K SA PS S
Sbjct: 175 SPPRPLERSVGQLPSPPLLPTPPPK-ASSKTTKNVTGQATLFQASSMK-SADPSLRGQLS 232
Query: 246 RPKAS 250
P S
Sbjct: 233 TPTGS 237
>gi|18087853 phosphatase and actin regulator 3 isoform 1 [Homo
sapiens]
Length = 559
Score = 229 bits (584), Expect = 6e-60
Identities = 164/436 (37%), Positives = 225/436 (51%), Gaps = 24/436 (5%)
Query: 208 PPKPASRNTTREAAGSSHSKKTTGSKASASPSTSSTSSRPKASKETVSSKAGTVGTTKGK 267
PP P S T E A T + S SS + A+K +S
Sbjct: 139 PPTPKSETLTSEDAQPGSPLATGTDQVSLDKPLSSAAHLDDAAKMPSASSGEEADAGS-- 196
Query: 268 RKTDKQPITSHLSSDTTTSGTSDLKGEPAETRVESFKLEQTVPGAEEQNTGKF-KSMVPP 326
P T+ LS + + D P E V +P + + K K++
Sbjct: 197 ----LLPTTNELSQALAGADSLDSPPRPLERSVGQLPSPPLLPTPPPKASSKTTKNVTGQ 252
Query: 327 PPVAPAPSPLAPPLPLEDQCITASDTPVVLVSVGADLPVSALDPSQLLWAEEPTNRTTLY 386
+ A S + L Q T + +P L +V LP S + +L A +R +
Sbjct: 253 ATLFQASSMKSADPSLRGQLSTPTGSPH-LTTVHRPLPPSRVI-EELHRALATKHRQDSF 310
Query: 387 SGT---GLSVNRENAKCFTTKE-ELGKTVPQLLTPGLMGESSESFSASEDEGHREYQAND 442
G G R + + T E GK + + E+ + + +E N
Sbjct: 311 QGRESKGSPKKRLDVRLSRTSSVERGKEREEAWSFDGALENKRTAAKESEENKENLIINS 370
Query: 443 SDSDGPILYTDDEDEDEDEDGSGESALASKIRRR---DTLAIKLGNRPSKKELEDKNILQ 499
D +LY +DE+ +S ++ + R+ + LA+KL NRPSK+ELED+NI
Sbjct: 371 ELKDDLLLY-------QDEEALNDSIISGTLPRKCKKELLAVKLRNRPSKQELEDRNIFP 423
Query: 500 RTSEEERQEIRQQIGTKLVRRLSQRPTTEELEQRNILKQKNEEEEQEAKMELKRRLSRKL 559
R ++EERQEIRQQI KL +RLSQRP EELE+RNILKQ+N++ EQE + E+K+RL+RKL
Sbjct: 424 RRTDEERQEIRQQIEMKLSKRLSQRPAVEELERRNILKQRNDQTEQEERREIKQRLTRKL 483
Query: 560 SLRPTVAELQARRIL-RFNEYVEVTDSPDYDRRADKPWARLTPADKAAIRKELNEFKSTE 618
+ RPTV EL+ R+IL RF++YVEV + DYDRRADKPW RL+ ADKAAIRKELNE+KS E
Sbjct: 484 NQRPTVDELRDRKILIRFSDYVEVAKAQDYDRRADKPWTRLSAADKAAIRKELNEYKSNE 543
Query: 619 MEVHEESRQFTRFHRP 634
MEVH S+ TRFHRP
Sbjct: 544 MEVHASSKHLTRFHRP 559
Score = 99.0 bits (245), Expect = 1e-20
Identities = 76/247 (30%), Positives = 121/247 (48%), Gaps = 10/247 (4%)
Query: 6 DGLDKASIANSDGPTAGSQTPPFKRKGKLSTIGKIFKPWKWRKKKTSDKFRETSAVLERK 65
D +D+ A + +G +TPP +R KL+T+G+IFKPWKWRKKK ++K ++T++ LE+K
Sbjct: 40 DEMDQTPPARPEYLVSGIRTPPVRRNSKLATLGRIFKPWKWRKKK-NEKLKQTTSALEKK 98
Query: 66 ISTRQSREELIRRGVLKELPDQDGDVTVNFENSNGHMIPIGEESTREENVVKSEEGNGSV 125
++ RQ REELI++G+L E+ +QD + + G E T + + SE+
Sbjct: 99 MAGRQGREELIKKGLL-EMMEQDAE-SKTCNPDGGPRSVQSEPPTPKSETLTSEDAQPG- 155
Query: 126 SEKTPPLEEQAEDKKENTENHSETPAAPALPPSAPPKPRPKPKPKKSPVPPKGATAGASH 185
S ++ + DK ++ H + A S P + + A AGA
Sbjct: 156 SPLATGTDQVSLDKPLSSAAHLDDAAKMPSASSGEEADAGSLLPTTNEL--SQALAGADS 213
Query: 186 KGDEVPPIKKNT-KAPGKQ-APVPPPKPASRNTTREAAGSSHSKKTTGSKASASPSTSST 243
P++++ + P P PPPK AS TT+ G + + + K SA PS
Sbjct: 214 LDSPPRPLERSVGQLPSPPLLPTPPPK-ASSKTTKNVTGQATLFQASSMK-SADPSLRGQ 271
Query: 244 SSRPKAS 250
S P S
Sbjct: 272 LSTPTGS 278
>gi|34304356 phosphatase and actin regulator 3 isoform 3 [Homo
sapiens]
Length = 448
Score = 225 bits (574), Expect = 8e-59
Identities = 167/458 (36%), Positives = 235/458 (51%), Gaps = 34/458 (7%)
Query: 187 GDEVPPIKKNTKAPGKQAPVPPPK-PASRNTTREAAGSSHSKKTTGSKASASPSTSSTSS 245
G PP+++N+K P K +N + S+ KK G +
Sbjct: 15 GIRTPPVRRNSKLATLGRIFKPWKWRKKKNEKLKQTTSALEKKMAGRQGREELIKKGLLE 74
Query: 246 RPKASKETVSSKAGTVGTTKGKRKTDKQPITSHLSSDTTTSGTSDLKGEPAETRVESFKL 305
+ E+ T G R +P T S+T TS + G P T + L
Sbjct: 75 MMEQDAESK-----TCNPDGGPRSVQSEPPTP--KSETLTSEDAQ-PGSPLATGTDQVSL 126
Query: 306 EQTVPGAEEQNTGKFKSMVPPPPVAPA-PSPLAPPLPLEDQCITASDTPVVLVSVGADLP 364
++ + A + ++ + A PS L Q T + +P L +V LP
Sbjct: 127 DKPLSSAAHLDDAGQATLFQASSMKSADPS-------LRGQLSTPTGSPH-LTTVHRPLP 178
Query: 365 VSALDPSQLLWAEEPTNRTTLYSGT---GLSVNRENAKCFTTKE-ELGKTVPQLLTPGLM 420
S + +L A +R + G G R + + T E GK + +
Sbjct: 179 PSRVI-EELHRALATKHRQDSFQGRESKGSPKKRLDVRLSRTSSVERGKEREEAWSFDGA 237
Query: 421 GESSESFSASEDEGHREYQANDSDSDGPILYTDDEDEDEDEDGSGESALASKIRRR---D 477
E+ + + +E N D +LY +DE+ +S ++ + R+ +
Sbjct: 238 LENKRTAAKESEENKENLIINSELKDDLLLY-------QDEEALNDSIISGTLPRKCKKE 290
Query: 478 TLAIKLGNRPSKKELEDKNILQRTSEEERQEIRQQIGTKLVRRLSQRPTTEELEQRNILK 537
LA+KL NRPSK+ELED+NI R ++EERQEIRQQI KL +RLSQRP EELE+RNILK
Sbjct: 291 LLAVKLRNRPSKQELEDRNIFPRRTDEERQEIRQQIEMKLSKRLSQRPAVEELERRNILK 350
Query: 538 QKNEEEEQEAKMELKRRLSRKLSLRPTVAELQARRIL-RFNEYVEVTDSPDYDRRADKPW 596
Q+N++ EQE + E+K+RL+RKL+ RPTV EL+ R+IL RF++YVEV + DYDRRADKPW
Sbjct: 351 QRNDQTEQEERREIKQRLTRKLNQRPTVDELRDRKILIRFSDYVEVAKAQDYDRRADKPW 410
Query: 597 ARLTPADKAAIRKELNEFKSTEMEVHEESRQFTRFHRP 634
RL+ ADKAAIRKELNE+KS EMEVH S+ TRFHRP
Sbjct: 411 TRLSAADKAAIRKELNEYKSNEMEVHASSKHLTRFHRP 448
Score = 84.7 bits (208), Expect = 2e-16
Identities = 39/83 (46%), Positives = 63/83 (75%), Gaps = 2/83 (2%)
Query: 8 LDKASIANSDGPTAGSQTPPFKRKGKLSTIGKIFKPWKWRKKKTSDKFRETSAVLERKIS 67
+D+ A + +G +TPP +R KL+T+G+IFKPWKWRKKK ++K ++T++ LE+K++
Sbjct: 1 MDQTPPARPEYLVSGIRTPPVRRNSKLATLGRIFKPWKWRKKK-NEKLKQTTSALEKKMA 59
Query: 68 TRQSREELIRRGVLKELPDQDGD 90
RQ REELI++G+L E+ +QD +
Sbjct: 60 GRQGREELIKKGLL-EMMEQDAE 81
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 70.5 bits (171), Expect = 5e-12
Identities = 115/525 (21%), Positives = 192/525 (36%), Gaps = 49/525 (9%)
Query: 107 EESTREENVVKSEEGNGSVSE-KTPPLEEQAEDKKENTENHSETPAAPALPPSAPPKPRP 165
EE +EE + EE G E K+PP EE A +KE E +PA S +
Sbjct: 480 EEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAK 539
Query: 166 KPKPKKSPVPPKG-ATAGASHKGDEVPPIKKNTKAPGKQAPVPPPKPASRNTTREAAGSS 224
P KSP K A A + P K+ K+P A V P+ A EA +
Sbjct: 540 SPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSP---AEVKSPEKAKSPAKEEAKSPA 596
Query: 225 HSKKTTGSKASASPSTSSTSSRPKASKETVSSKAGTVGTTKGKRKTDKQPITSH--LSSD 282
+K +K+ S + KE S A K K T ++ + S +
Sbjct: 597 EAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPE 656
Query: 283 TTTSGTSDLKGEPAETRVESFKLEQTVPGAEEQNTGKFKSMVPPPPVAPAPSPLAPPLPL 342
+ + + P + +S + ++ AE ++ K KS P A +P P+
Sbjct: 657 KEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKS--PVKEEAKSPEKAKSPVKE 714
Query: 343 EDQCITASDTPVVLVSVGADLPVSALDPSQLLWAEEPTNRTTLYSGTGLSVNRENAKCFT 402
E + + +P V A P A P + EE + + E AK
Sbjct: 715 EAKSPEKAKSP---VKEEAKTPEKAKSPVK----EE-------------AKSPEKAKSPE 754
Query: 403 TKEELGKTVPQLLTPGLMGESS--ESFSASEDEGHREYQANDSDSDGPILYTDDEDEDED 460
+ L P+ TP S + F +E + + P+ +D E
Sbjct: 755 KAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPL--KEDAKAPEK 812
Query: 461 EDGSGESALASKIRRRDTLAIKLGNRPSKKELEDKNILQRTSEEERQEIRQQIGTKLVRR 520
E E + +K+ P K E E +T EE+++ +++ K +
Sbjct: 813 EIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKT--EEKKDSKKEEAPK---K 867
Query: 521 LSQRPTTEELEQRNILKQKNEEEEQEAKMELKRRLSRKLSLRPT-----VAELQARRILR 575
+ +P EE K+ E+ +E+K+E K+ + PT A+++ + +
Sbjct: 868 EAPKPKVEE------KKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAK 921
Query: 576 FNEYVEVTDSPDYDRRADKPWARLTPADKAAIRKELNEFKSTEME 620
E EV D +A +P + A +K+ E K+ + E
Sbjct: 922 PKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPE 966
Score = 54.7 bits (130), Expect = 3e-07
Identities = 60/242 (24%), Positives = 86/242 (35%), Gaps = 23/242 (9%)
Query: 21 AGSQTPPFKRKGKLSTIGKIFKPWKWRKKKTSD-KFRETSAVLERKISTRQSREELIRRG 79
A S F K K ++ P K + D K E + ++ + EE +
Sbjct: 774 ARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEV 833
Query: 80 VLKELPDQDGDVTVNFENSNGHMIPIGEES--TREENVVKSEEGNGSVSEKTPPL----- 132
+KE P + E P EE +++E K E V EK P
Sbjct: 834 KVKEPPKKA-------EEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPK 886
Query: 133 -------EEQAEDKKENTENHSETPAAPALPPSAPPKPRPKPKPKKSPVPPKGATAGASH 185
+E+AEDKK+ E PA + A PK + + KK P K
Sbjct: 887 ESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTE-VAKKEPDDAKAKEPSKPA 945
Query: 186 KGDEVPPIKKNTKAPGKQAPVPPPKPASRNTTREAAGSSHSKKTTGSKASASPSTSSTSS 245
+ E P KK+TK + P PK ++ + S K KA S ST S
Sbjct: 946 EKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDS 1005
Query: 246 RP 247
+P
Sbjct: 1006 KP 1007
Score = 52.4 bits (124), Expect = 1e-06
Identities = 115/595 (19%), Positives = 201/595 (33%), Gaps = 91/595 (15%)
Query: 33 KLSTIGKIFKPWKWRKKKTSDKFRETSAVLERKISTRQSREELIRRGVLKELPDQDGDVT 92
K+ ++ K K K +K + + ++E + Q EE+ KE +++G
Sbjct: 428 KIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEE-KEAKEEEGKEE 486
Query: 93 VNFENSNGH------MIPIGEESTREENVVKS---EEGNGSVSEKTP------------- 130
E P EE+ E KS EE K+P
Sbjct: 487 EGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKS 546
Query: 131 ------PLEEQAEDKKENTENHSETPAAPALPPSAPPKPRPKPKPKKSPVPPKGATAGAS 184
P +E+A+ E E +PA S P + KSP K S
Sbjct: 547 PEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKS 606
Query: 185 HKGDEVP-------PIKKNTKAPGKQAPVPPPKPASRNTTREAAGSSHSKKTTGSKASAS 237
+E P+K+ K+P A V P+ A ++ T+E A S K+ + + S
Sbjct: 607 PVKEEAKSPAEAKSPVKEEAKSP---AEVKSPEKA-KSPTKEEAKSPEKAKSPEKEEAKS 662
Query: 238 PSTSST-----SSRPKASKETVSSKAGTVGTTKGKRKTD-------KQPITSHLSS---- 281
P + + + P+ +K V ++A + K K + K P+ S
Sbjct: 663 PEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKA 722
Query: 282 --------DTTTSGTSDLKGE---------PAETRVESFKL-EQTVPGAEEQNT--GKFK 321
T S +K E P + + K E P EE + KF
Sbjct: 723 KSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFP 782
Query: 322 SMVPPPPVAPAPSPLAPPLPL-EDQCITASDTPVVLVSVGADLPVSALDPSQLLWAEEPT 380
P SP PL ED + P PV + Q + +EP
Sbjct: 783 EKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIP---KKEEVKSPVKEEEKPQEVKVKEPP 839
Query: 381 NRTTLYSGTGLSVNRENAKCFTTKEELGK------TVPQLLTPGLMGESSESFSASEDEG 434
+ E K + KEE K V + P + A ++E
Sbjct: 840 KKAEEEKAPATPKTEE--KKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEA 897
Query: 435 HREYQANDSDSDGP--ILYTDDEDEDEDEDGSGESALASKIRRRDTLAIKLGNRPSKKEL 492
+ + + + P + +D E + + + +K + A K P KK+
Sbjct: 898 EDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDT 957
Query: 493 EDKNILQRTSEEERQEIRQQIGTKLVRRLSQRPTTEELEQRNILKQKNEEEEQEA 547
+++ ++ E+ + E + + K + + +P E+ E+ + QK+ + ++A
Sbjct: 958 KEEK-AKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKA 1011
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 63.9 bits (154), Expect = 4e-10
Identities = 85/367 (23%), Positives = 133/367 (36%), Gaps = 47/367 (12%)
Query: 16 SDGPTAGSQTPPFKRKGKLSTIGKIFKPWK--WRKKKTSDKFRETSAVLERKISTRQSRE 73
S P + PP K K WK WR+ K+ K K+ S
Sbjct: 487 SPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKK----------KLGVSVSPS 536
Query: 74 ELIRRGVLKELPDQDGDVTVNFENSNGHMIPIGEESTREENVVKSEEGNGSVSEKTPPLE 133
RR ++ + + +S+ G S+R + S S S +
Sbjct: 537 RARRR---RKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSR----H 589
Query: 134 EQAEDKKENTENHSETPAAPALPPSAPPKP-RPKPKPKKSPVPPKGATAGASHKGDEVPP 192
+ + + S +P+ PS P P RP + K P PP G S K PP
Sbjct: 590 SSFSGSRSRSRSFSSSPS-----PSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPP 644
Query: 193 IKKNTKAPGKQAPVP-PPKPA----SRNTTREAAGSSHSKKTTGSKASASPSTSSTSSRP 247
+A APVP P KP +R R A + +GS + + S S +SSR
Sbjct: 645 AP--PQATKTTAPVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRS 702
Query: 248 KA-SKETVSSKAGTVGTTKGKRKTDKQPITSHLSSDTTTSGTSDLKGEPAETRVESFKLE 306
++ S +VSS + ++ D + + + L+S S S PA+TR E K +
Sbjct: 703 RSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLAS--PVSSASSRSPAPAQTRKEKGKSK 760
Query: 307 QTVPGAEEQNTGKFKSMVPPPPVAP-----------APSPLAPPLPLEDQCITASDTPVV 355
+ G +E+ + S PP P P P P + + + +
Sbjct: 761 KE-DGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQAPPGQPQQGTFVAHKEIKLT 819
Query: 356 LVSVGAD 362
L++ AD
Sbjct: 820 LLNKAAD 826
Score = 53.5 bits (127), Expect = 6e-07
Identities = 56/246 (22%), Positives = 92/246 (37%), Gaps = 21/246 (8%)
Query: 108 ESTREENVVKSEEGNGSVSEKTPPLEEQAEDKKENTENHSETPAAPALPPSAPPKPRPKP 167
E RE + +E E ++ E +++ + E P P+P
Sbjct: 433 EREREREHERDKERQRRKEEWERERAKRDEKDRQHRDRDREKEREKEKGKPKPRSPQPPS 492
Query: 168 KPKKSPVPPKGATAGASHKGDEVPPIKKNTKAPGKQAPV---PPPKPASRNTTREAAGSS 224
+ + P T + DE + +K+P K+ V P R T+ +A +S
Sbjct: 493 RQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKTSASSASAS 552
Query: 225 HSKKTTGSKASASPSTSSTSSRPKASKETVSSKAGTVGTTKGKRKTDKQPITSHLSSDTT 284
+S +++ +S S S SS S +S + SS++ + G R + +S S T
Sbjct: 553 NSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTP 612
Query: 285 TSGTSDL--KGEPAETRVESFKLEQTVPGAEEQNTGKFKSMVPPPP-----VAPAPSPLA 337
+ + KGEPA PG + + K + P PP AP P P
Sbjct: 613 SPHRPSIRTKGEPAPP-----------PGKAGEKSVKKPAPPPAPPQATKTTAPVPEPTK 661
Query: 338 PPLPLE 343
P P E
Sbjct: 662 PGDPRE 667
Score = 35.0 bits (79), Expect = 0.21
Identities = 37/164 (22%), Positives = 61/164 (37%), Gaps = 13/164 (7%)
Query: 166 KPKPKKSPVPPKGATAGASHKGDEVPPIKKNTKAPGKQAPVPPPKPASRNTTREAAGSSH 225
K K S PPK A A K + P + +QAP P+ + +E +
Sbjct: 769 KRKRDSSTQPPKSAKPPAGGKSSQQP-------STPQQAPPGQPQQGTFVAHKEIKLTLL 821
Query: 226 SKKTT-GSKASASPSTSSTSSRPKASKETVSSKAGTVGTTKGKRKTDKQPITSHLSSDTT 284
+K GS+ PS S P A + S G+ G R +P +
Sbjct: 822 NKAADKGSRKRYEPSDKDRQSPPPAKRPNTSPDRGSRDRKSGGRLGSPKPERQRGQNSKA 881
Query: 285 TSGTSDLKGE-----PAETRVESFKLEQTVPGAEEQNTGKFKSM 323
+ +D K + + ++V S + + PGA +GK ++
Sbjct: 882 PAAPADRKRQLSPQSKSSSKVTSVPGKASDPGAASTKSGKASTL 925
Score = 33.1 bits (74), Expect = 0.80
Identities = 42/193 (21%), Positives = 68/193 (35%), Gaps = 32/193 (16%)
Query: 104 PIGEESTREENVVKSEEGNGSVSEKTPPLEEQAEDKKENTENHSETPAAPALPPSAPPKP 163
P+ S+R ++ + G S+K ++E+ + +T+ P A PP+
Sbjct: 738 PVSSASSRSPAPAQTRKEKGK-SKKEDGVKEEKRKRDSSTQ-----PPKSAKPPAGGKSS 791
Query: 164 RPKPKPKKSPVPPKGATAGASHKGDEVPPIKKNTKAPGKQAPVP------PPKPASRNTT 217
+ P+++P +HK ++ + K ++ P P PA R T
Sbjct: 792 QQPSTPQQAPPGQPQQGTFVAHKEIKLTLLNKAADKGSRKRYEPSDKDRQSPPPAKRPNT 851
Query: 218 REAAGSSHSK-------------KTTGSKASASP-------STSSTSSRPKASKETVSSK 257
GS K + SKA A+P S S SS S +S
Sbjct: 852 SPDRGSRDRKSGGRLGSPKPERQRGQNSKAPAAPADRKRQLSPQSKSSSKVTSVPGKASD 911
Query: 258 AGTVGTTKGKRKT 270
G T GK T
Sbjct: 912 PGAASTKSGKAST 924
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 63.5 bits (153), Expect = 6e-10
Identities = 60/230 (26%), Positives = 75/230 (32%), Gaps = 17/230 (7%)
Query: 147 SETPAAPALPPSAPPKPRPKPKPKKSPVPPKGATAGASHKGDEVPPIKKNTKAPGKQAPV 206
S T P PS PP P P +P PP T PP P
Sbjct: 1552 STTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTT 1611
Query: 207 PPP--KPASRNTTREAAGSSHSKKTTGSKASASPSTSST---SSRPKASKETVSSKAGTV 261
PPP P+ TT +S + + S P+T++T ++ P T S T
Sbjct: 1612 PPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITT 1671
Query: 262 GTTKGKRKTDKQPITSHLSSDTTTSGTSDLKGEPAETRVESFKLEQTVPGAEEQNTGKFK 321
TT T PIT+ S TTT T P+ T S + T +
Sbjct: 1672 TTTPPPTTTPSSPITTTPSPPTTTMTT------PSPTTTPSSPITTTTTPSSTTTPS--- 1722
Query: 322 SMVPPPPVAPAPSPLAPPLPLEDQCITASDTPVVLVSVGADLPVSALDPS 371
PPP PSP P P T T LP S P+
Sbjct: 1723 ---PPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPT 1769
Score = 61.6 bits (148), Expect = 2e-09
Identities = 62/244 (25%), Positives = 82/244 (33%), Gaps = 13/244 (5%)
Query: 149 TPAAPALPPSAPPKPRPKPKPKKSPVPPKGATAGASHKGDEVPPIKKNTKAPGKQAPVPP 208
TP+ P PS PP P +P PP T PPI T P P P
Sbjct: 1398 TPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSP- 1456
Query: 209 PKPASRNTTREAAGSSHSKKTTGSKASASPS--TSSTSSRPKASKETVSSKAGTVGTTKG 266
P S TT + TT S + +PS T++T++ P T S T T
Sbjct: 1457 --PISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPT---TTPSPPTTTPITPP 1511
Query: 267 KRKTDKQPIT--SHLSSDTTTSGTSDLKGEPAETRVESFKLEQTVPGAEEQNTGKFKSMV 324
T P T S ++ TTT + P T + T+P + +
Sbjct: 1512 ASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTT 1571
Query: 325 PPPPVAPAPSPLAPPLPLEDQCITASDTPV---VLVSVGADLPVSALDPSQLLWAEEPTN 381
PPP P+P P P T T + P + P PT+
Sbjct: 1572 PPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTS 1631
Query: 382 RTTL 385
TTL
Sbjct: 1632 TTTL 1635
Score = 58.2 bits (139), Expect = 2e-08
Identities = 58/260 (22%), Positives = 83/260 (31%), Gaps = 28/260 (10%)
Query: 129 TPPLEEQAEDKKENTENHSETPAAPALPPSAPPKPRPKPKPKKSPVPPKGATAGASHKGD 188
TPP + TP+ P + PP P +P+ P +T
Sbjct: 1463 TPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTT 1522
Query: 189 EVPPIKKNTKAPGKQAPVPPPK-----PASRNTTREAAGSSHSKKTTGSK---ASASPST 240
PP T P P PP P S T S TT + + SP T
Sbjct: 1523 PSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPT 1582
Query: 241 SSTSSRPKASKETVSSKAGTVGTTKGKRKTDKQPITSHLSSDTTTSGTSDLKGEPAETRV 300
++T S P T+ TT T P T + TTT + P T +
Sbjct: 1583 TTTPSPP------------TITTTTPPPTTTPSPPT----TTTTTPPPTTTPSPPTTTPI 1626
Query: 301 ESFKLEQTVPGAEEQNTGKFKSMVPPPPVAPAPSPLAPPLPLEDQCITASDTPVVLVSVG 360
T+P + + PPP P+P P P IT + TP +
Sbjct: 1627 TPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSP----PITTTTTPPPTTTPS 1682
Query: 361 ADLPVSALDPSQLLWAEEPT 380
+ + + P+ + PT
Sbjct: 1683 SPITTTPSPPTTTMTTPSPT 1702
Score = 56.6 bits (135), Expect = 7e-08
Identities = 63/260 (24%), Positives = 82/260 (31%), Gaps = 30/260 (11%)
Query: 147 SETPAAPALPPSAPPKPRPKPKPKKSPVPPKGATAGASHKGDEVPPIKKNTKAPGKQAPV 206
S T P PS P P P +P PP T PPI T P P
Sbjct: 1412 STTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPS 1471
Query: 207 PP----------PKPASRNTTREAAGSSHSKKTTGSKASASPSTSSTSSRPKASKETVSS 256
PP P P + TT ++ S TT +P S+T+ P T S
Sbjct: 1472 PPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTT---TPITPPASTTTLPP----TTTPS 1524
Query: 257 KAGTVGTTKGKRKTDKQPITSHL---SSDTTTSGTSDLKGEPAETRVESFKLEQTVPGAE 313
T TT T P T+ + +S TT T+ P T + P
Sbjct: 1525 PPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTT 1584
Query: 314 EQNTGKFKSMVPPPPVAPA--------PSPLAPPLPLEDQCIT--ASDTPVVLVSVGADL 363
+ + PPP P+ P P P P IT S T + + +
Sbjct: 1585 TPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPP 1644
Query: 364 PVSALDPSQLLWAEEPTNRT 383
P + P PT T
Sbjct: 1645 PTTTTTPPPTTTPSPPTTTT 1664
Score = 41.2 bits (95), Expect = 0.003
Identities = 46/205 (22%), Positives = 69/205 (33%), Gaps = 13/205 (6%)
Query: 192 PIKKNTKAPGKQAPVPPPKPASRNTTREAAGSSHSKKTTGS---KASASPSTSSTSSRPK 248
P+ K P P P P S T S TT + + SP ++T++ P
Sbjct: 1391 PMDKCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPP 1450
Query: 249 ASKETVSSKAGTV---GTTKGKRKTDKQPITSHLSSDTTTSGT---SDLKGEPAETRVES 302
+ + T TT T P T+ S TTT+ T + P T +
Sbjct: 1451 TTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITP 1510
Query: 303 FKLEQTVPGAEEQNTGKFKSMVPPPPVAPAP---SPLAPPLPLEDQCITASDTPVVLVSV 359
T+P + + PPP P+P +P+ PP T + +P +
Sbjct: 1511 PASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTT 1570
Query: 360 GADLPVSALDPSQLLWAEEPTNRTT 384
P + P PT TT
Sbjct: 1571 -TPPPTTTPSPPTTTTPSPPTITTT 1594
Score = 37.7 bits (86), Expect = 0.033
Identities = 41/198 (20%), Positives = 68/198 (34%), Gaps = 21/198 (10%)
Query: 100 GHMIPIGEESTREENVVKSEEGNGSVSEKTPPLEEQAEDKKENTENHSETPAAPALPPSA 159
G P T V + G+ + T P+ T ++TP + +
Sbjct: 4123 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 4182
Query: 160 PPKPRPKPKPKKSPVPPKGATAGASHKGDEVPPIKKNTKAPGKQAPVPPPK--------- 210
P P P ++ P +TA + PP + +T + P +
Sbjct: 4183 TVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLP 4242
Query: 211 PASRNTTREAAGSSHSKKTTGSKASASPSTSSTSSRPKASKETVSSKAGTVGTTKGKRKT 270
PA T+ + + TT + SP S+T+S P T GTT G +
Sbjct: 4243 PAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTP---------TRGTTTG---S 4290
Query: 271 DKQPITSHLSSDTTTSGT 288
P S + + TT++ T
Sbjct: 4291 SSAPTPSTVQTTTTSAWT 4308
Score = 36.6 bits (83), Expect = 0.073
Identities = 51/283 (18%), Positives = 85/283 (30%), Gaps = 16/283 (5%)
Query: 100 GHMIPIGEESTREENVVKSEEGNGSVSEKTPPLEEQAEDKKENTENHSETPAAPALPPSA 159
G P T V + G+ + T P+ T ++TP + +
Sbjct: 1915 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 1974
Query: 160 PPKPRPKPKPKKSP-----VPPKGATAGASHKGDEVP---PIKKNTKAPGKQAPVPPPKP 211
P P P ++P T + G + P PI T P P
Sbjct: 1975 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2034
Query: 212 ASRNTTREAAGSSHSKKTTGSKASASPSTSSTSSRP---KASKETVSSKAGTVGTTKGKR 268
+ T + T + +P T++T+ P +T ++ T TT
Sbjct: 2035 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2094
Query: 269 KT---DKQPITSHLSSDTTTSGTSDLKG--EPAETRVESFKLEQTVPGAEEQNTGKFKSM 323
T + P T+ +++ TT + T G P T + + P T +
Sbjct: 2095 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2154
Query: 324 VPPPPVAPAPSPLAPPLPLEDQCITASDTPVVLVSVGADLPVS 366
V P P+P P T + G P +
Sbjct: 2155 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2197
Score = 36.6 bits (83), Expect = 0.073
Identities = 51/283 (18%), Positives = 85/283 (30%), Gaps = 16/283 (5%)
Query: 100 GHMIPIGEESTREENVVKSEEGNGSVSEKTPPLEEQAEDKKENTENHSETPAAPALPPSA 159
G P T V + G+ + T P+ T ++TP + +
Sbjct: 2145 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2204
Query: 160 PPKPRPKPKPKKSP-----VPPKGATAGASHKGDEVP---PIKKNTKAPGKQAPVPPPKP 211
P P P ++P T + G + P PI T P P
Sbjct: 2205 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2264
Query: 212 ASRNTTREAAGSSHSKKTTGSKASASPSTSSTSSRP---KASKETVSSKAGTVGTTKGKR 268
+ T + T + +P T++T+ P +T ++ T TT
Sbjct: 2265 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2324
Query: 269 KT---DKQPITSHLSSDTTTSGTSDLKG--EPAETRVESFKLEQTVPGAEEQNTGKFKSM 323
T + P T+ +++ TT + T G P T + + P T +
Sbjct: 2325 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2384
Query: 324 VPPPPVAPAPSPLAPPLPLEDQCITASDTPVVLVSVGADLPVS 366
V P P+P P T + G P +
Sbjct: 2385 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2427
Score = 36.6 bits (83), Expect = 0.073
Identities = 51/283 (18%), Positives = 85/283 (30%), Gaps = 16/283 (5%)
Query: 100 GHMIPIGEESTREENVVKSEEGNGSVSEKTPPLEEQAEDKKENTENHSETPAAPALPPSA 159
G P T V + G+ + T P+ T ++TP + +
Sbjct: 2375 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2434
Query: 160 PPKPRPKPKPKKSP-----VPPKGATAGASHKGDEVP---PIKKNTKAPGKQAPVPPPKP 211
P P P ++P T + G + P PI T P P
Sbjct: 2435 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2494
Query: 212 ASRNTTREAAGSSHSKKTTGSKASASPSTSSTSSRP---KASKETVSSKAGTVGTTKGKR 268
+ T + T + +P T++T+ P +T ++ T TT
Sbjct: 2495 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2554
Query: 269 KT---DKQPITSHLSSDTTTSGTSDLKG--EPAETRVESFKLEQTVPGAEEQNTGKFKSM 323
T + P T+ +++ TT + T G P T + + P T +
Sbjct: 2555 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2614
Query: 324 VPPPPVAPAPSPLAPPLPLEDQCITASDTPVVLVSVGADLPVS 366
V P P+P P T + G P +
Sbjct: 2615 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2657
Score = 36.6 bits (83), Expect = 0.073
Identities = 51/283 (18%), Positives = 85/283 (30%), Gaps = 16/283 (5%)
Query: 100 GHMIPIGEESTREENVVKSEEGNGSVSEKTPPLEEQAEDKKENTENHSETPAAPALPPSA 159
G P T V + G+ + T P+ T ++TP + +
Sbjct: 2605 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2664
Query: 160 PPKPRPKPKPKKSP-----VPPKGATAGASHKGDEVP---PIKKNTKAPGKQAPVPPPKP 211
P P P ++P T + G + P PI T P P
Sbjct: 2665 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2724
Query: 212 ASRNTTREAAGSSHSKKTTGSKASASPSTSSTSSRP---KASKETVSSKAGTVGTTKGKR 268
+ T + T + +P T++T+ P +T ++ T TT
Sbjct: 2725 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2784
Query: 269 KT---DKQPITSHLSSDTTTSGTSDLKG--EPAETRVESFKLEQTVPGAEEQNTGKFKSM 323
T + P T+ +++ TT + T G P T + + P T +
Sbjct: 2785 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2844
Query: 324 VPPPPVAPAPSPLAPPLPLEDQCITASDTPVVLVSVGADLPVS 366
V P P+P P T + G P +
Sbjct: 2845 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2887
Score = 36.6 bits (83), Expect = 0.073
Identities = 51/283 (18%), Positives = 85/283 (30%), Gaps = 16/283 (5%)
Query: 100 GHMIPIGEESTREENVVKSEEGNGSVSEKTPPLEEQAEDKKENTENHSETPAAPALPPSA 159
G P T V + G+ + T P+ T ++TP + +
Sbjct: 2835 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2894
Query: 160 PPKPRPKPKPKKSP-----VPPKGATAGASHKGDEVP---PIKKNTKAPGKQAPVPPPKP 211
P P P ++P T + G + P PI T P P
Sbjct: 2895 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2954
Query: 212 ASRNTTREAAGSSHSKKTTGSKASASPSTSSTSSRP---KASKETVSSKAGTVGTTKGKR 268
+ T + T + +P T++T+ P +T ++ T TT
Sbjct: 2955 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3014
Query: 269 KT---DKQPITSHLSSDTTTSGTSDLKG--EPAETRVESFKLEQTVPGAEEQNTGKFKSM 323
T + P T+ +++ TT + T G P T + + P T +
Sbjct: 3015 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3074
Query: 324 VPPPPVAPAPSPLAPPLPLEDQCITASDTPVVLVSVGADLPVS 366
V P P+P P T + G P +
Sbjct: 3075 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3117
Score = 36.6 bits (83), Expect = 0.073
Identities = 51/283 (18%), Positives = 85/283 (30%), Gaps = 16/283 (5%)
Query: 100 GHMIPIGEESTREENVVKSEEGNGSVSEKTPPLEEQAEDKKENTENHSETPAAPALPPSA 159
G P T V + G+ + T P+ T ++TP + +
Sbjct: 3065 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3124
Query: 160 PPKPRPKPKPKKSP-----VPPKGATAGASHKGDEVP---PIKKNTKAPGKQAPVPPPKP 211
P P P ++P T + G + P PI T P P
Sbjct: 3125 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3184
Query: 212 ASRNTTREAAGSSHSKKTTGSKASASPSTSSTSSRP---KASKETVSSKAGTVGTTKGKR 268
+ T + T + +P T++T+ P +T ++ T TT
Sbjct: 3185 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3244
Query: 269 KT---DKQPITSHLSSDTTTSGTSDLKG--EPAETRVESFKLEQTVPGAEEQNTGKFKSM 323
T + P T+ +++ TT + T G P T + + P T +
Sbjct: 3245 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3304
Query: 324 VPPPPVAPAPSPLAPPLPLEDQCITASDTPVVLVSVGADLPVS 366
V P P+P P T + G P +
Sbjct: 3305 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3347
Score = 36.6 bits (83), Expect = 0.073
Identities = 51/283 (18%), Positives = 85/283 (30%), Gaps = 16/283 (5%)
Query: 100 GHMIPIGEESTREENVVKSEEGNGSVSEKTPPLEEQAEDKKENTENHSETPAAPALPPSA 159
G P T V + G+ + T P+ T ++TP + +
Sbjct: 3295 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3354
Query: 160 PPKPRPKPKPKKSP-----VPPKGATAGASHKGDEVP---PIKKNTKAPGKQAPVPPPKP 211
P P P ++P T + G + P PI T P P
Sbjct: 3355 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3414
Query: 212 ASRNTTREAAGSSHSKKTTGSKASASPSTSSTSSRP---KASKETVSSKAGTVGTTKGKR 268
+ T + T + +P T++T+ P +T ++ T TT
Sbjct: 3415 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3474
Query: 269 KT---DKQPITSHLSSDTTTSGTSDLKG--EPAETRVESFKLEQTVPGAEEQNTGKFKSM 323
T + P T+ +++ TT + T G P T + + P T +
Sbjct: 3475 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3534
Query: 324 VPPPPVAPAPSPLAPPLPLEDQCITASDTPVVLVSVGADLPVS 366
V P P+P P T + G P +
Sbjct: 3535 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3577
Score = 36.6 bits (83), Expect = 0.073
Identities = 51/283 (18%), Positives = 85/283 (30%), Gaps = 16/283 (5%)
Query: 100 GHMIPIGEESTREENVVKSEEGNGSVSEKTPPLEEQAEDKKENTENHSETPAAPALPPSA 159
G P T V + G+ + T P+ T ++TP + +
Sbjct: 3525 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3584
Query: 160 PPKPRPKPKPKKSP-----VPPKGATAGASHKGDEVP---PIKKNTKAPGKQAPVPPPKP 211
P P P ++P T + G + P PI T P P
Sbjct: 3585 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3644
Query: 212 ASRNTTREAAGSSHSKKTTGSKASASPSTSSTSSRP---KASKETVSSKAGTVGTTKGKR 268
+ T + T + +P T++T+ P +T ++ T TT
Sbjct: 3645 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3704
Query: 269 KT---DKQPITSHLSSDTTTSGTSDLKG--EPAETRVESFKLEQTVPGAEEQNTGKFKSM 323
T + P T+ +++ TT + T G P T + + P T +
Sbjct: 3705 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3764
Query: 324 VPPPPVAPAPSPLAPPLPLEDQCITASDTPVVLVSVGADLPVS 366
V P P+P P T + G P +
Sbjct: 3765 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3807
Score = 36.6 bits (83), Expect = 0.073
Identities = 51/283 (18%), Positives = 85/283 (30%), Gaps = 16/283 (5%)
Query: 100 GHMIPIGEESTREENVVKSEEGNGSVSEKTPPLEEQAEDKKENTENHSETPAAPALPPSA 159
G P T V + G+ + T P+ T ++TP + +
Sbjct: 3755 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3814
Query: 160 PPKPRPKPKPKKSP-----VPPKGATAGASHKGDEVP---PIKKNTKAPGKQAPVPPPKP 211
P P P ++P T + G + P PI T P P
Sbjct: 3815 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3874
Query: 212 ASRNTTREAAGSSHSKKTTGSKASASPSTSSTSSRP---KASKETVSSKAGTVGTTKGKR 268
+ T + T + +P T++T+ P +T ++ T TT
Sbjct: 3875 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3934
Query: 269 KT---DKQPITSHLSSDTTTSGTSDLKG--EPAETRVESFKLEQTVPGAEEQNTGKFKSM 323
T + P T+ +++ TT + T G P T + + P T +
Sbjct: 3935 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3994
Query: 324 VPPPPVAPAPSPLAPPLPLEDQCITASDTPVVLVSVGADLPVS 366
V P P+P P T + G P +
Sbjct: 3995 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 4037
Score = 35.8 bits (81), Expect = 0.12
Identities = 63/339 (18%), Positives = 102/339 (30%), Gaps = 35/339 (10%)
Query: 100 GHMIPIGEESTREENVVKSEEGNGSVSEKTPPLEEQAEDKKENTENHSETPAAPALPPSA 159
G P T V + G+ + T P+ T ++TP + +
Sbjct: 3985 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 4044
Query: 160 PPKPRPKPKPKKSP-----VPPKGATAGASHKGDEVP---PIKKNTKA------PGKQAP 205
P P P ++P T + G + P PI T G Q P
Sbjct: 4045 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 4104
Query: 206 VPPPKPASRNTTREAAGSSHSKKTT---GSKASASPSTSSTSSR-PKASKETVSSKAGTV 261
P + T + TT + + +P+ + T ++ P + T ++
Sbjct: 4105 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 4164
Query: 262 GTTKGKRKTDKQPITSHLSSDTTTSGTSDLKGEPAETRVESFKLEQTVPGAEEQNTGKFK 321
T G + PIT+ + T + T G P T T P AE +
Sbjct: 4165 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHT--------STAPIAELTTSN--- 4213
Query: 322 SMVPPPPVAPAPSPLAPPLPLEDQCITASDTPVVLVSVGADLPVSALDPSQLLWA---EE 378
PPP + + + PL + S P + P + P+
Sbjct: 4214 ---PPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSP 4270
Query: 379 PTNRTTLYSGTGLSVNRENAKCFTTKEELGKTVPQLLTP 417
P + TT GT + T + T TP
Sbjct: 4271 PPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTP 4309
Score = 35.4 bits (80), Expect = 0.16
Identities = 49/273 (17%), Positives = 83/273 (30%), Gaps = 16/273 (5%)
Query: 110 TREENVVKSEEGNGSVSEKTPPLEEQAEDKKENTENHSETPAAPALPPSAPPKPRPKPKP 169
T V + G+ + T P+ T ++TP + + P P P
Sbjct: 1902 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 1961
Query: 170 KKSP-----VPPKGATAGASHKGDEVP---PIKKNTKAPGKQAPVPPPKPASRNTTREAA 221
++P T + G + P PI T P P + T
Sbjct: 1962 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2021
Query: 222 GSSHSKKTTGSKASASPSTSSTSSRP---KASKETVSSKAGTVGTTKGKRKT---DKQPI 275
+ T + +P T++T+ P +T ++ T TT T + P
Sbjct: 2022 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2081
Query: 276 TSHLSSDTTTSGTSDLKG--EPAETRVESFKLEQTVPGAEEQNTGKFKSMVPPPPVAPAP 333
T+ +++ TT + T G P T + + P T + V P P
Sbjct: 2082 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2141
Query: 334 SPLAPPLPLEDQCITASDTPVVLVSVGADLPVS 366
+P P T + G P +
Sbjct: 2142 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2174
Score = 33.5 bits (75), Expect = 0.61
Identities = 27/117 (23%), Positives = 38/117 (32%), Gaps = 1/117 (0%)
Query: 149 TPAAPALPPSAPPKPRPKPKP-KKSPVPPKGATAGASHKGDEVPPIKKNTKAPGKQAPVP 207
TP+ P + PP P +P PP S PI T P P
Sbjct: 1664 TPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSP 1723
Query: 208 PPKPASRNTTREAAGSSHSKKTTGSKASASPSTSSTSSRPKASKETVSSKAGTVGTT 264
PP + + + TT + S ++T P + T S + T TT
Sbjct: 1724 PPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTT 1780
Score = 32.7 bits (73), Expect = 1.0
Identities = 34/149 (22%), Positives = 53/149 (35%), Gaps = 18/149 (12%)
Query: 146 HSETPAAPALPPSAPPKPRPKPKPKKSPVPPKGATAGASHKGDEVPPIKKNTKAP----- 200
H+ T L S PP P+ +S P T + P I+ + AP
Sbjct: 4200 HTSTAPIAELTTSNPPPESSTPQTSRSTSSP--LTESTTLLSTLPPAIEMTSTAPPSTPT 4257
Query: 201 ------GKQAPVPPPKPASRNTTREAAGSSHSKKTTGSKASASPSTSSTSSRPKASKETV 254
G PPP +TT G+ TTGS ++ +PST T++ +
Sbjct: 4258 APTTTSGGHTLSPPP-----STTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPT 4312
Query: 255 SSKAGTVGTTKGKRKTDKQPITSHLSSDT 283
++ T G R + + +DT
Sbjct: 4313 PLSTPSIIRTTGLRPYPSSVLICCVLNDT 4341
>gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2
[Homo sapiens]
Length = 1481
Score = 62.4 bits (150), Expect = 1e-09
Identities = 89/331 (26%), Positives = 133/331 (40%), Gaps = 53/331 (16%)
Query: 29 KRKGKLSTIGKIFKPWKWRKKKTSDKFRETSAVLERKISTRQSREELIRRGVLKELPDQD 88
K GK S +F P RK+ +S + +++ LE K R + E K PD +
Sbjct: 414 KMDGKESKGSPVFLP---RKENSSVEAKDSG--LESKKLPRSVKLE-------KSAPDTE 461
Query: 89 -GDVT-VNFENSNGH---MIPIGEESTREENVVKSEEGNGSVSEKTPPLEEQAEDKKENT 143
+VT +N E N + + E S E+++VK + G+ K L+E+ KE
Sbjct: 462 LVNVTHLNTEVKNSSDTGKVKLDENS--EKHLVKDLKAQGTRDSKPIALKEEIVTPKETE 519
Query: 144 ENHSETPAA-PALPPSAPPKPRPKPKPKKSPVPPKGATAGASHKGDEVPPIKKNTKAPGK 202
+ ETP P + PP P P P+ P+PP +PPI A +
Sbjct: 520 TSEKETPPPLPTIASPPPPLPTTTPPPQTPPLPP-------------LPPI----PALPQ 562
Query: 203 QAPVPPPKPASRNTTREAAGSSHSKKTTGSKASASPSTSSTSSRPKASKETVSSKAGTVG 262
Q P+PP +PA A+ +S +T SK SA S +++ + S +T S +
Sbjct: 563 QPPLPPSQPAFSQV--PASSTSTLPPSTHSKTSAVSSQANSQPPVQVSVKTQVSVTAAIP 620
Query: 263 TTKGKRKTDKQPITSHLSSDTTTSGTSDLKGEPAETRVESFKLEQTVPGAEEQNTGKFKS 322
K P+ L D D P ET + V +EQ T +
Sbjct: 621 HLK-TSTLPPLPLPPLLPGD-------DDMDSPKETLP-----SKPVKKEKEQRTRHLLT 667
Query: 323 MVPPPPVAPAPSPLAPPLPLEDQCITASDTP 353
+P PP P L+PP E + IT P
Sbjct: 668 DLPLPPELPG-GDLSPPDSPEPKAITPPQQP 697
Score = 33.1 bits (74), Expect = 0.80
Identities = 26/126 (20%), Positives = 50/126 (39%), Gaps = 14/126 (11%)
Query: 53 DKFRETSAVLERKISTRQSREELIRRGVLKELPDQDGDVTVNFENSNGHMIPIGEESTRE 112
+ ++ + L S +Q E + LKE P S ++P E++T E
Sbjct: 1151 EALNQSISALTEATSQQQDSETMAPEESLKEAP------------SAPVILPSAEQTTLE 1198
Query: 113 ENVVKSEEGN--GSVSEKTPPLEEQAEDKKENTENHSETPAAPALPPSAPPKPRPKPKPK 170
+ ++ N + + +E A +EN + + P P P+ P + + +P
Sbjct: 1199 ASSTPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAEKRPP 1258
Query: 171 KSPVPP 176
+ P PP
Sbjct: 1259 EPPGPP 1264
>gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1
[Homo sapiens]
Length = 1490
Score = 62.4 bits (150), Expect = 1e-09
Identities = 89/331 (26%), Positives = 133/331 (40%), Gaps = 53/331 (16%)
Query: 29 KRKGKLSTIGKIFKPWKWRKKKTSDKFRETSAVLERKISTRQSREELIRRGVLKELPDQD 88
K GK S +F P RK+ +S + +++ LE K R + E K PD +
Sbjct: 414 KMDGKESKGSPVFLP---RKENSSVEAKDSG--LESKKLPRSVKLE-------KSAPDTE 461
Query: 89 -GDVT-VNFENSNGH---MIPIGEESTREENVVKSEEGNGSVSEKTPPLEEQAEDKKENT 143
+VT +N E N + + E S E+++VK + G+ K L+E+ KE
Sbjct: 462 LVNVTHLNTEVKNSSDTGKVKLDENS--EKHLVKDLKAQGTRDSKPIALKEEIVTPKETE 519
Query: 144 ENHSETPAA-PALPPSAPPKPRPKPKPKKSPVPPKGATAGASHKGDEVPPIKKNTKAPGK 202
+ ETP P + PP P P P+ P+PP +PPI A +
Sbjct: 520 TSEKETPPPLPTIASPPPPLPTTTPPPQTPPLPP-------------LPPI----PALPQ 562
Query: 203 QAPVPPPKPASRNTTREAAGSSHSKKTTGSKASASPSTSSTSSRPKASKETVSSKAGTVG 262
Q P+PP +PA A+ +S +T SK SA S +++ + S +T S +
Sbjct: 563 QPPLPPSQPAFSQV--PASSTSTLPPSTHSKTSAVSSQANSQPPVQVSVKTQVSVTAAIP 620
Query: 263 TTKGKRKTDKQPITSHLSSDTTTSGTSDLKGEPAETRVESFKLEQTVPGAEEQNTGKFKS 322
K P+ L D D P ET + V +EQ T +
Sbjct: 621 HLK-TSTLPPLPLPPLLPGD-------DDMDSPKETLP-----SKPVKKEKEQRTRHLLT 667
Query: 323 MVPPPPVAPAPSPLAPPLPLEDQCITASDTP 353
+P PP P L+PP E + IT P
Sbjct: 668 DLPLPPELPG-GDLSPPDSPEPKAITPPQQP 697
Score = 33.9 bits (76), Expect = 0.47
Identities = 36/146 (24%), Positives = 53/146 (36%), Gaps = 41/146 (28%)
Query: 53 DKFRETSAVLERKISTRQSREELIRRGVLKELPDQDGDVTVNFENSNGHMIPIGEESTRE 112
+ ++ + L S +Q E + LKE P S ++P E++T E
Sbjct: 1151 EALNQSISALTEATSQQQDSETMAPEESLKEAP------------SAPVILPSAEQTTLE 1198
Query: 113 EN----------------VVKSEEGNGSVSEKTPPLEEQAEDKKENTENHSETPAAP--- 153
+ ++K++E GS LEE DK + TP P
Sbjct: 1199 ASSTPADMQNILAVLLSQLMKTQEPAGS-------LEENNSDKNSGPQGPRRTPTMPQEE 1251
Query: 154 --ALPPS-APPKPRPKPKPKKSPVPP 176
A PP PP+ RP P P PP
Sbjct: 1252 AAACPPHILPPEKRPPEPPGPPPPPP 1277
Score = 30.0 bits (66), Expect = 6.8
Identities = 38/184 (20%), Positives = 62/184 (33%), Gaps = 13/184 (7%)
Query: 109 STREENVVKSEEGNGSVSEKTPPLEEQAEDKKENTENHSETPAAPALPPSAPPKPRPKPK 168
S E N K+ G T P EE A P P PP PP P +
Sbjct: 1226 SLEENNSDKNSGPQGPRRTPTMPQEEAAACPPHILPPEKRPPEPPGPPPPPPPPPLVEGD 1285
Query: 169 PKKSPVPPKGATAGASHKGDEVPPIKKNTKAPGKQAPVPPPKPASRNTTREAAGSSHSKK 228
+P A A + P + P + + P + ++R G++ +
Sbjct: 1286 LSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEHQALRPMEYSTRPRPNRTYGNTDGPE 1345
Query: 229 TTGSKASASPSTSSTSSRPKASKETVSSKAGTVGTTKGKRKTDKQPITSHLSSDTTTSGT 288
T ++ T +S P ++ V T K +T + SHL ++ GT
Sbjct: 1346 T----GFSAIDTDERNSGPALTESLVQ--------TLVKNRTFSGSL-SHLGESSSYQGT 1392
Query: 289 SDLK 292
++
Sbjct: 1393 GSVQ 1396
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 62.0 bits (149), Expect = 2e-09
Identities = 107/526 (20%), Positives = 186/526 (35%), Gaps = 98/526 (18%)
Query: 109 STREENVVKSEEGNGSVSEKT---------PPLEEQAEDKKENTENHSETPAAPALPPSA 159
S E++ + EE G ++K PP + A+ + ++ S
Sbjct: 85 SDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEESSDDDDEEDQKKQ 144
Query: 160 PPKPRPKPKPKKSPVPPKGATAGASHK---GDEVPP-----------IKKNTKAPGKQAP 205
P + KP+ K + PPK A + S ++ PP +K TKAP K
Sbjct: 145 PVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPK--- 201
Query: 206 VPPPKPASRNTTREAAGSSHSKKTTGSKASASPSTSSTSSRPKASKETVSSKAGTVGTTK 265
P + A + +AA SS S ++ S + ++ + + K+ V +KA T
Sbjct: 202 --PARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATT 259
Query: 266 GKRKTDKQPITSHLSSDTTTSGTSDLKGEPAETRVESFKLEQTVPGAEEQNTGKFKSMVP 325
RK+ SS+ ++S + + +P + + + +VP K P
Sbjct: 260 PTRKSS--------SSEDSSSDEEEEQKKPMKNKPGPY---SSVPPPSAPPPKKSLGTQP 308
Query: 326 PPPVAPAPSPLAPPLPLEDQCITASDTPVVLVSVGADLPVSALDPSQLLWAEEPTNRTTL 385
P P+ D+ ++S+ + + P AE ++ +
Sbjct: 309 PKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDS 368
Query: 386 YSG---------TGLSVNRENAKCFTTKEELGKTV----------PQLLTPGLMGESSES 426
S G + N N TTK K +LLT SSE
Sbjct: 369 DSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEE 428
Query: 427 FSASEDEGHREYQ------------------------ANDSDSDGPILYTDDEDEDEDED 462
S+S +E + + DS SD +D +E+E+
Sbjct: 429 ESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSD-----SDSSSSEEEEE 483
Query: 463 GSGESALASKIRRRDTLAIKLGNRPSKKELEDKNILQRTSEEERQEIRQQIGTKLVRRLS 522
+ +SA+ K ++ + G PSK K + ++ + ++ KL + S
Sbjct: 484 KTSKSAVKKKPQK-----VAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGS 538
Query: 523 QRPT------TEELEQRNILKQKNEEEEQEAKMELKRRLSRKLSLR 562
RP T L +N KN EEE+E K + +S+ SL+
Sbjct: 539 PRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLK 584
Score = 51.2 bits (121), Expect = 3e-06
Identities = 116/572 (20%), Positives = 195/572 (34%), Gaps = 106/572 (18%)
Query: 10 KASIANSDGPTAGSQTPPFKRKGKLSTIGKIF------KPWKWRKKKTSDKFRETSAVLE 63
KA ++SD ++ PP +K K++ + KP + K + K +S+
Sbjct: 163 KAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSS 222
Query: 64 RKISTRQSREELIRRGVLKELPDQDGDVTVNFENSNGHMIPIGEESTREENVVKSEEGNG 123
S+ S EE K +P + P+ +T SE+ +
Sbjct: 223 SSSSSDDSEEEKAAATPKKTVPKKQVVAKA----------PVKAATTPTRKSSSSEDSSS 272
Query: 124 SVSEKTPPLEEQAEDKKENTENHSETPAAPALPPSAPPKPRPKPKPKKSPVPPKGATAGA 183
E EQ + K +S P P + PPK +P K V + +
Sbjct: 273 DEEE------EQKKPMKNKPGPYSSVPP----PSAPPPKKSLGTQPPKKAVEKQQPVESS 322
Query: 184 SHKGDEVPPIKKNTKAPGKQAPVPPPKPASRNTTREAAGSSHSKKTTGSKASASPSTSST 243
DE + K P +A V + A SS S + S+ +PS +
Sbjct: 323 EDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAG 382
Query: 244 SSRPKASKETVSSKAGTVGTTKGKRKTDKQPITSHLSSDTTTSGTSDLKGEPAETR-VES 302
+++ ++K V++K+ V KQP+ G+ TR +S
Sbjct: 383 TTKNSSNKPAVTTKSPAVKPA----AAPKQPVGG---------------GQKLLTRKADS 423
Query: 303 FKLEQTVPGAEEQNTGKFKSMVPPPPVAPAPSPLAPPLPLEDQCITASDTPVVLVSVGAD 362
E+ +EE+ T K + P A A A P G+
Sbjct: 424 SSSEEESSSSEEEKTKKMVATTKPKATAKA----------------ALSLPAKQAPQGSR 467
Query: 363 LPVSALDPSQLLWAEEPTNRTTLYSGTGLSVNRENAKCFTTKEELGKTVPQLLTPGLMGE 422
S D S EE T+++ + K PQ + G
Sbjct: 468 DSSSDSDSSSSEEEEEKTSKSAV-----------------------KKKPQKVA----GG 500
Query: 423 SSESFSASEDEGHREYQANDSDSDGPILYTDDEDEDEDEDGSGESALASKIRRRDTLAIK 482
++ S AS +G E +N S SD E+E+E G G S + T A+
Sbjct: 501 AAPSKPASAKKGKAE-SSNSSSSD-----DSSEEEEEKLKGKG-SPRPQAPKANGTSALT 553
Query: 483 LGNRPSKKELEDKNILQRTSEEERQE---IRQQIGTKLVRRLSQRPTTEELEQRNILKQK 539
N + K E++ EEE+++ + + G+ R+ ++ E Q +K +
Sbjct: 554 AQNGKAAKNSEEE-------EEEKKKAAVVVSKSGSLKKRKQNEAAKEAETPQAKKIKLQ 606
Query: 540 NEEEEQEAKMELKRRLSRKLSLRPTVAELQAR 571
+ K KR S +R E+ +R
Sbjct: 607 TPNTFPKRKKGEKRASSPFRRVREEEIEVDSR 638
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 60.5 bits (145), Expect = 5e-09
Identities = 65/246 (26%), Positives = 87/246 (35%), Gaps = 27/246 (10%)
Query: 129 TPPLEEQAEDKKENTENHSETPAAPALPPSAPPKPRPKPKPKKSPVPPKGATAGASHKGD 188
T P E KE ++ PA P+ P +P P + +P PK T K
Sbjct: 445 TTPKEPAPTTPKEPAPTTTKKPA-----PTTPKEPAPTTPKETAPTTPKKLTPTTPEKLA 499
Query: 189 EVPPIKKNTKAPGKQAPVPPPKPASRN------TTREAAGSSHSKKTTGSKASASPSTSS 242
P K P + AP P +P TT +AA + K+ + T+
Sbjct: 500 PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTP 559
Query: 243 TSSRPKASKETV-SSKAGTVGTT--KGKRKTDKQPITSHLSSDTTTSGTSDLKGEPAETR 299
P KET ++ GT TT + T K+P L+ TT TS +PA T
Sbjct: 560 KEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTT 619
Query: 300 VESF------KLEQTVPGAEEQNTGK------FKSMVPPPPVAPAPSPLAPPLPLEDQCI 347
+ + T P T K K P P PAP LA P +
Sbjct: 620 PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELA-PTTTKGPTS 678
Query: 348 TASDTP 353
T SD P
Sbjct: 679 TTSDKP 684
Score = 56.6 bits (135), Expect = 7e-08
Identities = 56/198 (28%), Positives = 75/198 (37%), Gaps = 12/198 (6%)
Query: 129 TPPLEEQAEDKKENTENHSETPAAPALPPSAPPKPRPKPKPKK-SPVPPKGATAGASHKG 187
T P E KE + A L AP P+ KP PK+ +P KG T+ S K
Sbjct: 626 TTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK-KPAPKELAPTTTKGPTSTTSDKP 684
Query: 188 DEVPPIKKNTKAPGKQAPVPPPKPASRN------TTREAAGSSHSKKTTGSKASASPSTS 241
P + P + AP P KPA TT E + + +K+ T S ST
Sbjct: 685 APTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTP 744
Query: 242 STSSRPKASKETVSSKAGTVGTTKGKRKTDKQPITSHLSSDTTTSGTSDLKGEPAETRVE 301
S+ P S K V TTK T + T+ + D TT DL+ P T
Sbjct: 745 ELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTT--AKDKTTE--RDLRTTPETTTAA 800
Query: 302 SFKLEQTVPGAEEQNTGK 319
++T E+ K
Sbjct: 801 PKMTKETATTTEKTTESK 818
Score = 55.8 bits (133), Expect = 1e-07
Identities = 77/292 (26%), Positives = 105/292 (35%), Gaps = 39/292 (13%)
Query: 109 STREENVVKSEEGNGSVSEKTPPLEEQAEDKKENTENHSETPAAPALPPSAPPKPRPKPK 168
+T +E + + + K P E T++ TP PA P+ P KP P
Sbjct: 257 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPA--PTTPKKPAPTTP 314
Query: 169 PKKSPVP--PKGAT-------AGASHKGDEVPPIKKNTKAPGKQAPVPPPKPASRNTTRE 219
K P P PK T A + + P + AP K AP P +PA
Sbjct: 315 --KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEP 372
Query: 220 AAGSSHSKKTTGSKASASPSTSSTSSRPKASKETVSSKAGTVGTTKGKRKTDKQPITSHL 279
A ++ T K P+ ++T S P +KE + TTK T K+P
Sbjct: 373 APTTTKEPSPTTPK---EPAPTTTKSAPTTTKEPAPT------TTKSAPTTPKEP----- 418
Query: 280 SSDTTTSGTSDLKGEPAETRVESFKLEQTVPGAEEQNTGK------FKSMVPPPPVAPAP 333
S TT EPA T + K T P T K K P P PAP
Sbjct: 419 SPTTTKEPAPTTPKEPAPTTPK--KPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAP 476
Query: 334 SPLAPPLPLEDQCITASDTPVVLVSVGADLPVSALDPSQL--LWAEEPTNRT 383
+ P + +T + TP L + P + P +L EEPT T
Sbjct: 477 TTPKETAPTTPKKLTPT-TPEKLAPTTPEKP-APTTPEELAPTTPEEPTPTT 526
Score = 55.5 bits (132), Expect = 2e-07
Identities = 97/451 (21%), Positives = 146/451 (32%), Gaps = 45/451 (9%)
Query: 1 MDNAVDGLDKASIANSDGPTAGSQTPPFKRKGKLSTIGKIFKPWKWRKK--KTSDKFRET 58
+D A GLD + T+ +Q K++T KP R SD +ET
Sbjct: 85 VDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTA----KPINPRPSLPPNSDTSKET 140
Query: 59 SAVLERKISTRQSREELIRRGVLKELPDQDGDVTVNFENSNGHMIPIGEESTREENVVKS 118
S + ++ +T +++E K+ + T + + + ++ V+
Sbjct: 141 SLTVNKE-TTVETKETTTTN---KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK 196
Query: 119 EEGNGSVSEKTP----PLEEQAEDKKE--NTENHSETPAAPALPPSAPPKPRPKPKPKKS 172
+ K P P E KE +T TP P+ P +P P
Sbjct: 197 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 256
Query: 173 PVPPKGATAGASHKGDEVP--PIKKNTKAPG----KQAPVPPPKPA-------SRNTTRE 219
P + A P P TK P K AP P +PA + T +E
Sbjct: 257 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE 316
Query: 220 AAGSSHSKKTTGSKASASPSTSSTS-SRPKASKETVSSKAGTVGTTKGKRKTDKQ----- 273
A ++ + T + +P+T + + PK T K + T K+
Sbjct: 317 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 376
Query: 274 -----PITSHLSSDTTTSGTSDLKGEPAETRVESFKLEQTVPGAEEQNTGKFKSMVPPPP 328
P T + TTT EPA T +S T P T K + P
Sbjct: 377 TKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKS---APTTPKEPSPTTTKEPAPTTPKE 433
Query: 329 VAP-APSPLAPPLPLEDQCITASD-TPVVLVSVGADLPVSALDPSQLLWAEEPTNRTTLY 386
AP P AP P E T + P P + A + T
Sbjct: 434 PAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPT 493
Query: 387 SGTGLSVNRENAKCFTTKEELGKTVPQLLTP 417
+ L+ TT EEL T P+ TP
Sbjct: 494 TPEKLAPTTPEKPAPTTPEELAPTTPEEPTP 524
Score = 53.5 bits (127), Expect = 6e-07
Identities = 73/335 (21%), Positives = 111/335 (33%), Gaps = 60/335 (17%)
Query: 129 TPPLEEQAEDKKENTENHSE-----TPAAPA------LPPSAPPKPRPKPKPKKSPVPPK 177
T P E K+ T E TP PA L P+ P +P P + +P PK
Sbjct: 477 TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPK 536
Query: 178 GATAGASHKGDEVPPIKKNTKAPGKQAPV----------------------------PPP 209
A + P + P + AP P P
Sbjct: 537 AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 596
Query: 210 KPASRNTTREAAGSSHSKKTTGSKASASPSTSSTSSRPKASKETVSSKAGTVGTT--KGK 267
K + TT+E ++ K + +P+T + + ++ GT TT +
Sbjct: 597 KELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPA 656
Query: 268 RKTDKQPITSHLSSDTTTSGTSDLKGEPAETRVESFKLEQTVPGAEEQNTGKFKSMVPPP 327
T K+P L+ TT TS +PA T ++T P K P
Sbjct: 657 PTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP-----KETAPTTP-------KEPAPTT 704
Query: 328 PVAPAPSPLAPPLPLEDQCITASDT---PVVLVSVGADLPVSALDPSQLLWAEEPTNRTT 384
P PAP+ P P + T + T + S P + +P+ P
Sbjct: 705 PKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGV 764
Query: 385 LYSGTGLSVNRE---NAKCFTTKEELGKTVPQLLT 416
+ T + E AK TT+ +L +T P+ T
Sbjct: 765 PTTKTPAATKPEMTTTAKDKTTERDL-RTTPETTT 798
Score = 52.4 bits (124), Expect = 1e-06
Identities = 79/307 (25%), Positives = 109/307 (35%), Gaps = 43/307 (14%)
Query: 126 SEKTPPLEEQAEDKKENTENHSETPAAPALPPSAPPKPR-PKPKPKKSPVPPKGATAGAS 184
S TP +E A ++ ++ PA P SAP P+ P P K P P
Sbjct: 381 SPTTP--KEPAPTTTKSAPTTTKEPA-PTTTKSAPTTPKEPSPTTTKEPAP--------- 428
Query: 185 HKGDEVPPIKKNTKAPGKQAPVPPPKPASRNTTREAAGSSHSKKTTGSKASASPSTSSTS 244
P + P K AP P +PA T +E A ++ K + +P+T +
Sbjct: 429 -----TTPKEPAPTTPKKPAPTTPKEPAP-TTPKEPAPTTTKKPAPTTPKEPAPTTPKET 482
Query: 245 SRPKASKETVSSKAGTVGTTKGKRKTDKQPITSHLSSDTTTSGTSDLKGEPAETRVESFK 304
+ K T ++ TT K P T + TT EP T E +
Sbjct: 483 APTTPKKLTPTTPEKLAPTTPEK----PAPTTPEELAPTTPE-------EPTPTTPE--E 529
Query: 305 LEQTVPGAEEQNTGKFKSMVPPPPVAP-APSPLAPPLPLEDQCITASDTPVVLVSVGADL 363
T P A NT K + P AP P AP P E T T + A
Sbjct: 530 PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT 589
Query: 364 PVSALDPSQL--LWAEEPTNRT------TLYSGTGLSVNRENAKCFTTKEELGKTVPQLL 415
P +L +EPT+ T T GT + +E A TT +E T P+
Sbjct: 590 TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAP--TTPKEPAPTTPKGT 647
Query: 416 TPGLMGE 422
P + E
Sbjct: 648 APTTLKE 654
Score = 49.7 bits (117), Expect = 8e-06
Identities = 80/350 (22%), Positives = 118/350 (33%), Gaps = 46/350 (13%)
Query: 19 PTAGSQTPPFKRKGKLSTIGKIFKPWKWRKKKTSDKFRETSAVLERKISTRQSREELIRR 78
PT +T P KG T K +P KK + K + E +T +
Sbjct: 564 PTTPKETAPTTPKGTAPTTLK--EPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 621
Query: 79 GVLKELPDQDGDVTVNFENSNGHMIPIGEESTREENVVKSEEGNGSVSEKTPPLEEQAED 138
G P + T P + T + +E + +K P E
Sbjct: 622 GTAPTTPKEPAPTTPK------EPAPTTPKGTAPTTL---KEPAPTTPKKPAPKELAPTT 672
Query: 139 KKENTENHSETPAAPALPPSAPPKPR-PKPKPKKSPVPPKGATAGASHKGDEVPPIKKNT 197
K T S+ PA +AP P+ P P K P P T + P K
Sbjct: 673 TKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEP 732
Query: 198 ----KAPGKQAPV----PPPKPASRN-------TTREAAGSSHSKKTTGSKASAS----P 238
K+P + P P PK + TT+ A + TT +
Sbjct: 733 TTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT 792
Query: 239 STSSTSSRPKASKETVSSKAGTVGTTKGKRKTDKQPITSHLSSDTTTSGTSDLKGEPAET 298
+ +T++ PK +KET ++ T TT+ K +TS + DTT + LK
Sbjct: 793 TPETTTAAPKMTKETATT---TEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAP 849
Query: 299 RVESFKLEQTVPGAEEQN----TGKFK------SMVPPPPVAPAPSPLAP 338
+V + K +T+ E N T K K P P P +P P
Sbjct: 850 KVTTTK--KTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKP 897
Score = 32.7 bits (73), Expect = 1.0
Identities = 30/103 (29%), Positives = 40/103 (38%), Gaps = 9/103 (8%)
Query: 133 EEQAEDKKENTENHSETPAAPALPPSAPPKPRPKPKPKKSPVPPKGATAGASHK----GD 188
EE A+ K T + + TP P P AP KP KPK P K T K
Sbjct: 868 EETAKPKDRATNSKATTPK-PQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMP 926
Query: 189 EVPPIKKNTKAPGKQAPVPPPKPASR----NTTREAAGSSHSK 227
E+ P + +A + P P S+ N E AG + +
Sbjct: 927 ELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGE 969
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 60.5 bits (145), Expect = 5e-09
Identities = 65/246 (26%), Positives = 87/246 (35%), Gaps = 27/246 (10%)
Query: 129 TPPLEEQAEDKKENTENHSETPAAPALPPSAPPKPRPKPKPKKSPVPPKGATAGASHKGD 188
T P E KE ++ PA P+ P +P P + +P PK T K
Sbjct: 486 TTPKEPAPTTPKEPAPTTTKKPA-----PTTPKEPAPTTPKETAPTTPKKLTPTTPEKLA 540
Query: 189 EVPPIKKNTKAPGKQAPVPPPKPASRN------TTREAAGSSHSKKTTGSKASASPSTSS 242
P K P + AP P +P TT +AA + K+ + T+
Sbjct: 541 PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTP 600
Query: 243 TSSRPKASKETV-SSKAGTVGTT--KGKRKTDKQPITSHLSSDTTTSGTSDLKGEPAETR 299
P KET ++ GT TT + T K+P L+ TT TS +PA T
Sbjct: 601 KEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTT 660
Query: 300 VESF------KLEQTVPGAEEQNTGK------FKSMVPPPPVAPAPSPLAPPLPLEDQCI 347
+ + T P T K K P P PAP LA P +
Sbjct: 661 PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELA-PTTTKGPTS 719
Query: 348 TASDTP 353
T SD P
Sbjct: 720 TTSDKP 725
Score = 56.6 bits (135), Expect = 7e-08
Identities = 56/198 (28%), Positives = 75/198 (37%), Gaps = 12/198 (6%)
Query: 129 TPPLEEQAEDKKENTENHSETPAAPALPPSAPPKPRPKPKPKK-SPVPPKGATAGASHKG 187
T P E KE + A L AP P+ KP PK+ +P KG T+ S K
Sbjct: 667 TTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK-KPAPKELAPTTTKGPTSTTSDKP 725
Query: 188 DEVPPIKKNTKAPGKQAPVPPPKPASRN------TTREAAGSSHSKKTTGSKASASPSTS 241
P + P + AP P KPA TT E + + +K+ T S ST
Sbjct: 726 APTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTP 785
Query: 242 STSSRPKASKETVSSKAGTVGTTKGKRKTDKQPITSHLSSDTTTSGTSDLKGEPAETRVE 301
S+ P S K V TTK T + T+ + D TT DL+ P T
Sbjct: 786 ELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTT--AKDKTTE--RDLRTTPETTTAA 841
Query: 302 SFKLEQTVPGAEEQNTGK 319
++T E+ K
Sbjct: 842 PKMTKETATTTEKTTESK 859
Score = 55.8 bits (133), Expect = 1e-07
Identities = 77/292 (26%), Positives = 105/292 (35%), Gaps = 39/292 (13%)
Query: 109 STREENVVKSEEGNGSVSEKTPPLEEQAEDKKENTENHSETPAAPALPPSAPPKPRPKPK 168
+T +E + + + K P E T++ TP PA P+ P KP P
Sbjct: 298 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPA--PTTPKKPAPTTP 355
Query: 169 PKKSPVP--PKGAT-------AGASHKGDEVPPIKKNTKAPGKQAPVPPPKPASRNTTRE 219
K P P PK T A + + P + AP K AP P +PA
Sbjct: 356 --KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEP 413
Query: 220 AAGSSHSKKTTGSKASASPSTSSTSSRPKASKETVSSKAGTVGTTKGKRKTDKQPITSHL 279
A ++ T K P+ ++T S P +KE + TTK T K+P
Sbjct: 414 APTTTKEPSPTTPK---EPAPTTTKSAPTTTKEPAPT------TTKSAPTTPKEP----- 459
Query: 280 SSDTTTSGTSDLKGEPAETRVESFKLEQTVPGAEEQNTGK------FKSMVPPPPVAPAP 333
S TT EPA T + K T P T K K P P PAP
Sbjct: 460 SPTTTKEPAPTTPKEPAPTTPK--KPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAP 517
Query: 334 SPLAPPLPLEDQCITASDTPVVLVSVGADLPVSALDPSQL--LWAEEPTNRT 383
+ P + +T + TP L + P + P +L EEPT T
Sbjct: 518 TTPKETAPTTPKKLTPT-TPEKLAPTTPEKP-APTTPEELAPTTPEEPTPTT 567
Score = 55.5 bits (132), Expect = 2e-07
Identities = 97/451 (21%), Positives = 146/451 (32%), Gaps = 45/451 (9%)
Query: 1 MDNAVDGLDKASIANSDGPTAGSQTPPFKRKGKLSTIGKIFKPWKWRKK--KTSDKFRET 58
+D A GLD + T+ +Q K++T KP R SD +ET
Sbjct: 126 VDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTA----KPINPRPSLPPNSDTSKET 181
Query: 59 SAVLERKISTRQSREELIRRGVLKELPDQDGDVTVNFENSNGHMIPIGEESTREENVVKS 118
S + ++ +T +++E K+ + T + + + ++ V+
Sbjct: 182 SLTVNKE-TTVETKETTTTN---KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK 237
Query: 119 EEGNGSVSEKTP----PLEEQAEDKKE--NTENHSETPAAPALPPSAPPKPRPKPKPKKS 172
+ K P P E KE +T TP P+ P +P P
Sbjct: 238 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 297
Query: 173 PVPPKGATAGASHKGDEVP--PIKKNTKAPG----KQAPVPPPKPA-------SRNTTRE 219
P + A P P TK P K AP P +PA + T +E
Sbjct: 298 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE 357
Query: 220 AAGSSHSKKTTGSKASASPSTSSTS-SRPKASKETVSSKAGTVGTTKGKRKTDKQ----- 273
A ++ + T + +P+T + + PK T K + T K+
Sbjct: 358 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 417
Query: 274 -----PITSHLSSDTTTSGTSDLKGEPAETRVESFKLEQTVPGAEEQNTGKFKSMVPPPP 328
P T + TTT EPA T +S T P T K + P
Sbjct: 418 TKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKS---APTTPKEPSPTTTKEPAPTTPKE 474
Query: 329 VAP-APSPLAPPLPLEDQCITASD-TPVVLVSVGADLPVSALDPSQLLWAEEPTNRTTLY 386
AP P AP P E T + P P + A + T
Sbjct: 475 PAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPT 534
Query: 387 SGTGLSVNRENAKCFTTKEELGKTVPQLLTP 417
+ L+ TT EEL T P+ TP
Sbjct: 535 TPEKLAPTTPEKPAPTTPEELAPTTPEEPTP 565
Score = 53.5 bits (127), Expect = 6e-07
Identities = 73/335 (21%), Positives = 111/335 (33%), Gaps = 60/335 (17%)
Query: 129 TPPLEEQAEDKKENTENHSE-----TPAAPA------LPPSAPPKPRPKPKPKKSPVPPK 177
T P E K+ T E TP PA L P+ P +P P + +P PK
Sbjct: 518 TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPK 577
Query: 178 GATAGASHKGDEVPPIKKNTKAPGKQAPV----------------------------PPP 209
A + P + P + AP P P
Sbjct: 578 AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 637
Query: 210 KPASRNTTREAAGSSHSKKTTGSKASASPSTSSTSSRPKASKETVSSKAGTVGTT--KGK 267
K + TT+E ++ K + +P+T + + ++ GT TT +
Sbjct: 638 KELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPA 697
Query: 268 RKTDKQPITSHLSSDTTTSGTSDLKGEPAETRVESFKLEQTVPGAEEQNTGKFKSMVPPP 327
T K+P L+ TT TS +PA T ++T P K P
Sbjct: 698 PTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP-----KETAPTTP-------KEPAPTT 745
Query: 328 PVAPAPSPLAPPLPLEDQCITASDT---PVVLVSVGADLPVSALDPSQLLWAEEPTNRTT 384
P PAP+ P P + T + T + S P + +P+ P
Sbjct: 746 PKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGV 805
Query: 385 LYSGTGLSVNRE---NAKCFTTKEELGKTVPQLLT 416
+ T + E AK TT+ +L +T P+ T
Sbjct: 806 PTTKTPAATKPEMTTTAKDKTTERDL-RTTPETTT 839
Score = 52.4 bits (124), Expect = 1e-06
Identities = 79/307 (25%), Positives = 109/307 (35%), Gaps = 43/307 (14%)
Query: 126 SEKTPPLEEQAEDKKENTENHSETPAAPALPPSAPPKPR-PKPKPKKSPVPPKGATAGAS 184
S TP +E A ++ ++ PA P SAP P+ P P K P P
Sbjct: 422 SPTTP--KEPAPTTTKSAPTTTKEPA-PTTTKSAPTTPKEPSPTTTKEPAP--------- 469
Query: 185 HKGDEVPPIKKNTKAPGKQAPVPPPKPASRNTTREAAGSSHSKKTTGSKASASPSTSSTS 244
P + P K AP P +PA T +E A ++ K + +P+T +
Sbjct: 470 -----TTPKEPAPTTPKKPAPTTPKEPAP-TTPKEPAPTTTKKPAPTTPKEPAPTTPKET 523
Query: 245 SRPKASKETVSSKAGTVGTTKGKRKTDKQPITSHLSSDTTTSGTSDLKGEPAETRVESFK 304
+ K T ++ TT K P T + TT EP T E +
Sbjct: 524 APTTPKKLTPTTPEKLAPTTPEK----PAPTTPEELAPTTPE-------EPTPTTPE--E 570
Query: 305 LEQTVPGAEEQNTGKFKSMVPPPPVAP-APSPLAPPLPLEDQCITASDTPVVLVSVGADL 363
T P A NT K + P AP P AP P E T T + A
Sbjct: 571 PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT 630
Query: 364 PVSALDPSQL--LWAEEPTNRT------TLYSGTGLSVNRENAKCFTTKEELGKTVPQLL 415
P +L +EPT+ T T GT + +E A TT +E T P+
Sbjct: 631 TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAP--TTPKEPAPTTPKGT 688
Query: 416 TPGLMGE 422
P + E
Sbjct: 689 APTTLKE 695
Score = 49.7 bits (117), Expect = 8e-06
Identities = 80/350 (22%), Positives = 118/350 (33%), Gaps = 46/350 (13%)
Query: 19 PTAGSQTPPFKRKGKLSTIGKIFKPWKWRKKKTSDKFRETSAVLERKISTRQSREELIRR 78
PT +T P KG T K +P KK + K + E +T +
Sbjct: 605 PTTPKETAPTTPKGTAPTTLK--EPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 662
Query: 79 GVLKELPDQDGDVTVNFENSNGHMIPIGEESTREENVVKSEEGNGSVSEKTPPLEEQAED 138
G P + T P + T + +E + +K P E
Sbjct: 663 GTAPTTPKEPAPTTPK------EPAPTTPKGTAPTTL---KEPAPTTPKKPAPKELAPTT 713
Query: 139 KKENTENHSETPAAPALPPSAPPKPR-PKPKPKKSPVPPKGATAGASHKGDEVPPIKKNT 197
K T S+ PA +AP P+ P P K P P T + P K
Sbjct: 714 TKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEP 773
Query: 198 ----KAPGKQAPV----PPPKPASRN-------TTREAAGSSHSKKTTGSKASAS----P 238
K+P + P P PK + TT+ A + TT +
Sbjct: 774 TTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT 833
Query: 239 STSSTSSRPKASKETVSSKAGTVGTTKGKRKTDKQPITSHLSSDTTTSGTSDLKGEPAET 298
+ +T++ PK +KET ++ T TT+ K +TS + DTT + LK
Sbjct: 834 TPETTTAAPKMTKETATT---TEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAP 890
Query: 299 RVESFKLEQTVPGAEEQN----TGKFK------SMVPPPPVAPAPSPLAP 338
+V + K +T+ E N T K K P P P +P P
Sbjct: 891 KVTTTK--KTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKP 938
Score = 32.7 bits (73), Expect = 1.0
Identities = 30/103 (29%), Positives = 40/103 (38%), Gaps = 9/103 (8%)
Query: 133 EEQAEDKKENTENHSETPAAPALPPSAPPKPRPKPKPKKSPVPPKGATAGASHK----GD 188
EE A+ K T + + TP P P AP KP KPK P K T K
Sbjct: 909 EETAKPKDRATNSKATTPK-PQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMP 967
Query: 189 EVPPIKKNTKAPGKQAPVPPPKPASR----NTTREAAGSSHSK 227
E+ P + +A + P P S+ N E AG + +
Sbjct: 968 ELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGE 1010
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 60.5 bits (145), Expect = 5e-09
Identities = 65/246 (26%), Positives = 87/246 (35%), Gaps = 27/246 (10%)
Query: 129 TPPLEEQAEDKKENTENHSETPAAPALPPSAPPKPRPKPKPKKSPVPPKGATAGASHKGD 188
T P E KE ++ PA P+ P +P P + +P PK T K
Sbjct: 538 TTPKEPAPTTPKEPAPTTTKKPA-----PTTPKEPAPTTPKETAPTTPKKLTPTTPEKLA 592
Query: 189 EVPPIKKNTKAPGKQAPVPPPKPASRN------TTREAAGSSHSKKTTGSKASASPSTSS 242
P K P + AP P +P TT +AA + K+ + T+
Sbjct: 593 PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTP 652
Query: 243 TSSRPKASKETV-SSKAGTVGTT--KGKRKTDKQPITSHLSSDTTTSGTSDLKGEPAETR 299
P KET ++ GT TT + T K+P L+ TT TS +PA T
Sbjct: 653 KEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTT 712
Query: 300 VESF------KLEQTVPGAEEQNTGK------FKSMVPPPPVAPAPSPLAPPLPLEDQCI 347
+ + T P T K K P P PAP LA P +
Sbjct: 713 PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELA-PTTTKGPTS 771
Query: 348 TASDTP 353
T SD P
Sbjct: 772 TTSDKP 777
Score = 56.6 bits (135), Expect = 7e-08
Identities = 56/198 (28%), Positives = 75/198 (37%), Gaps = 12/198 (6%)
Query: 129 TPPLEEQAEDKKENTENHSETPAAPALPPSAPPKPRPKPKPKK-SPVPPKGATAGASHKG 187
T P E KE + A L AP P+ KP PK+ +P KG T+ S K
Sbjct: 719 TTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK-KPAPKELAPTTTKGPTSTTSDKP 777
Query: 188 DEVPPIKKNTKAPGKQAPVPPPKPASRN------TTREAAGSSHSKKTTGSKASASPSTS 241
P + P + AP P KPA TT E + + +K+ T S ST
Sbjct: 778 APTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTP 837
Query: 242 STSSRPKASKETVSSKAGTVGTTKGKRKTDKQPITSHLSSDTTTSGTSDLKGEPAETRVE 301
S+ P S K V TTK T + T+ + D TT DL+ P T
Sbjct: 838 ELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTT--AKDKTTE--RDLRTTPETTTAA 893
Query: 302 SFKLEQTVPGAEEQNTGK 319
++T E+ K
Sbjct: 894 PKMTKETATTTEKTTESK 911
Score = 55.8 bits (133), Expect = 1e-07
Identities = 77/292 (26%), Positives = 105/292 (35%), Gaps = 39/292 (13%)
Query: 109 STREENVVKSEEGNGSVSEKTPPLEEQAEDKKENTENHSETPAAPALPPSAPPKPRPKPK 168
+T +E + + + K P E T++ TP PA P+ P KP P
Sbjct: 350 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPA--PTTPKKPAPTTP 407
Query: 169 PKKSPVP--PKGAT-------AGASHKGDEVPPIKKNTKAPGKQAPVPPPKPASRNTTRE 219
K P P PK T A + + P + AP K AP P +PA
Sbjct: 408 --KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEP 465
Query: 220 AAGSSHSKKTTGSKASASPSTSSTSSRPKASKETVSSKAGTVGTTKGKRKTDKQPITSHL 279
A ++ T K P+ ++T S P +KE + TTK T K+P
Sbjct: 466 APTTTKEPSPTTPK---EPAPTTTKSAPTTTKEPAPT------TTKSAPTTPKEP----- 511
Query: 280 SSDTTTSGTSDLKGEPAETRVESFKLEQTVPGAEEQNTGK------FKSMVPPPPVAPAP 333
S TT EPA T + K T P T K K P P PAP
Sbjct: 512 SPTTTKEPAPTTPKEPAPTTPK--KPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAP 569
Query: 334 SPLAPPLPLEDQCITASDTPVVLVSVGADLPVSALDPSQL--LWAEEPTNRT 383
+ P + +T + TP L + P + P +L EEPT T
Sbjct: 570 TTPKETAPTTPKKLTPT-TPEKLAPTTPEKP-APTTPEELAPTTPEEPTPTT 619
Score = 55.5 bits (132), Expect = 2e-07
Identities = 97/451 (21%), Positives = 146/451 (32%), Gaps = 45/451 (9%)
Query: 1 MDNAVDGLDKASIANSDGPTAGSQTPPFKRKGKLSTIGKIFKPWKWRKK--KTSDKFRET 58
+D A GLD + T+ +Q K++T KP R SD +ET
Sbjct: 178 VDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTA----KPINPRPSLPPNSDTSKET 233
Query: 59 SAVLERKISTRQSREELIRRGVLKELPDQDGDVTVNFENSNGHMIPIGEESTREENVVKS 118
S + ++ +T +++E K+ + T + + + ++ V+
Sbjct: 234 SLTVNKE-TTVETKETTTTN---KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK 289
Query: 119 EEGNGSVSEKTP----PLEEQAEDKKE--NTENHSETPAAPALPPSAPPKPRPKPKPKKS 172
+ K P P E KE +T TP P+ P +P P
Sbjct: 290 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 349
Query: 173 PVPPKGATAGASHKGDEVP--PIKKNTKAPG----KQAPVPPPKPA-------SRNTTRE 219
P + A P P TK P K AP P +PA + T +E
Sbjct: 350 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE 409
Query: 220 AAGSSHSKKTTGSKASASPSTSSTS-SRPKASKETVSSKAGTVGTTKGKRKTDKQ----- 273
A ++ + T + +P+T + + PK T K + T K+
Sbjct: 410 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 469
Query: 274 -----PITSHLSSDTTTSGTSDLKGEPAETRVESFKLEQTVPGAEEQNTGKFKSMVPPPP 328
P T + TTT EPA T +S T P T K + P
Sbjct: 470 TKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKS---APTTPKEPSPTTTKEPAPTTPKE 526
Query: 329 VAP-APSPLAPPLPLEDQCITASD-TPVVLVSVGADLPVSALDPSQLLWAEEPTNRTTLY 386
AP P AP P E T + P P + A + T
Sbjct: 527 PAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPT 586
Query: 387 SGTGLSVNRENAKCFTTKEELGKTVPQLLTP 417
+ L+ TT EEL T P+ TP
Sbjct: 587 TPEKLAPTTPEKPAPTTPEELAPTTPEEPTP 617
Score = 53.5 bits (127), Expect = 6e-07
Identities = 73/335 (21%), Positives = 111/335 (33%), Gaps = 60/335 (17%)
Query: 129 TPPLEEQAEDKKENTENHSE-----TPAAPA------LPPSAPPKPRPKPKPKKSPVPPK 177
T P E K+ T E TP PA L P+ P +P P + +P PK
Sbjct: 570 TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPK 629
Query: 178 GATAGASHKGDEVPPIKKNTKAPGKQAPV----------------------------PPP 209
A + P + P + AP P P
Sbjct: 630 AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 689
Query: 210 KPASRNTTREAAGSSHSKKTTGSKASASPSTSSTSSRPKASKETVSSKAGTVGTT--KGK 267
K + TT+E ++ K + +P+T + + ++ GT TT +
Sbjct: 690 KELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPA 749
Query: 268 RKTDKQPITSHLSSDTTTSGTSDLKGEPAETRVESFKLEQTVPGAEEQNTGKFKSMVPPP 327
T K+P L+ TT TS +PA T ++T P K P
Sbjct: 750 PTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP-----KETAPTTP-------KEPAPTT 797
Query: 328 PVAPAPSPLAPPLPLEDQCITASDT---PVVLVSVGADLPVSALDPSQLLWAEEPTNRTT 384
P PAP+ P P + T + T + S P + +P+ P
Sbjct: 798 PKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGV 857
Query: 385 LYSGTGLSVNRE---NAKCFTTKEELGKTVPQLLT 416
+ T + E AK TT+ +L +T P+ T
Sbjct: 858 PTTKTPAATKPEMTTTAKDKTTERDL-RTTPETTT 891
Score = 52.4 bits (124), Expect = 1e-06
Identities = 79/307 (25%), Positives = 109/307 (35%), Gaps = 43/307 (14%)
Query: 126 SEKTPPLEEQAEDKKENTENHSETPAAPALPPSAPPKPR-PKPKPKKSPVPPKGATAGAS 184
S TP +E A ++ ++ PA P SAP P+ P P K P P
Sbjct: 474 SPTTP--KEPAPTTTKSAPTTTKEPA-PTTTKSAPTTPKEPSPTTTKEPAP--------- 521
Query: 185 HKGDEVPPIKKNTKAPGKQAPVPPPKPASRNTTREAAGSSHSKKTTGSKASASPSTSSTS 244
P + P K AP P +PA T +E A ++ K + +P+T +
Sbjct: 522 -----TTPKEPAPTTPKKPAPTTPKEPAP-TTPKEPAPTTTKKPAPTTPKEPAPTTPKET 575
Query: 245 SRPKASKETVSSKAGTVGTTKGKRKTDKQPITSHLSSDTTTSGTSDLKGEPAETRVESFK 304
+ K T ++ TT K P T + TT EP T E +
Sbjct: 576 APTTPKKLTPTTPEKLAPTTPEK----PAPTTPEELAPTTPE-------EPTPTTPE--E 622
Query: 305 LEQTVPGAEEQNTGKFKSMVPPPPVAP-APSPLAPPLPLEDQCITASDTPVVLVSVGADL 363
T P A NT K + P AP P AP P E T T + A
Sbjct: 623 PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT 682
Query: 364 PVSALDPSQL--LWAEEPTNRT------TLYSGTGLSVNRENAKCFTTKEELGKTVPQLL 415
P +L +EPT+ T T GT + +E A TT +E T P+
Sbjct: 683 TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAP--TTPKEPAPTTPKGT 740
Query: 416 TPGLMGE 422
P + E
Sbjct: 741 APTTLKE 747
Score = 49.7 bits (117), Expect = 8e-06
Identities = 80/350 (22%), Positives = 118/350 (33%), Gaps = 46/350 (13%)
Query: 19 PTAGSQTPPFKRKGKLSTIGKIFKPWKWRKKKTSDKFRETSAVLERKISTRQSREELIRR 78
PT +T P KG T K +P KK + K + E +T +
Sbjct: 657 PTTPKETAPTTPKGTAPTTLK--EPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 714
Query: 79 GVLKELPDQDGDVTVNFENSNGHMIPIGEESTREENVVKSEEGNGSVSEKTPPLEEQAED 138
G P + T P + T + +E + +K P E
Sbjct: 715 GTAPTTPKEPAPTTPK------EPAPTTPKGTAPTTL---KEPAPTTPKKPAPKELAPTT 765
Query: 139 KKENTENHSETPAAPALPPSAPPKPR-PKPKPKKSPVPPKGATAGASHKGDEVPPIKKNT 197
K T S+ PA +AP P+ P P K P P T + P K
Sbjct: 766 TKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEP 825
Query: 198 ----KAPGKQAPV----PPPKPASRN-------TTREAAGSSHSKKTTGSKASAS----P 238
K+P + P P PK + TT+ A + TT +
Sbjct: 826 TTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT 885
Query: 239 STSSTSSRPKASKETVSSKAGTVGTTKGKRKTDKQPITSHLSSDTTTSGTSDLKGEPAET 298
+ +T++ PK +KET ++ T TT+ K +TS + DTT + LK
Sbjct: 886 TPETTTAAPKMTKETATT---TEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAP 942
Query: 299 RVESFKLEQTVPGAEEQN----TGKFK------SMVPPPPVAPAPSPLAP 338
+V + K +T+ E N T K K P P P +P P
Sbjct: 943 KVTTTK--KTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKP 990
Score = 47.4 bits (111), Expect = 4e-05
Identities = 56/258 (21%), Positives = 87/258 (33%), Gaps = 26/258 (10%)
Query: 107 EESTREENVVKSEEGNGSVSEKTPPLEEQAEDKKENTENHSETPAAPALPPSAPPKPRPK 166
EE T E +V +++E + S S + + +N+ + E + + + + K
Sbjct: 111 EEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKK 170
Query: 167 PKPKKSPVPPKGA-------------TAGASHKGDEVPPIKKNTKAPGKQAPVPPPKPAS 213
P PK V G+ T+ H P K + +PP S
Sbjct: 171 PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTS 230
Query: 214 RNTT----REAAGSSHSKKTTGSKASASPSTSSTSSRPKASKETVSSK--AGT----VGT 263
+ T+ +E + TT + S +TS++ S E S+K A T
Sbjct: 231 KETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP 290
Query: 264 TKGKRKTDKQPITSHLSSDTTTSGTSDLKGEPAETRVESFKLEQTVPGAEEQNTGKFKSM 323
T T K P + T T+ P E + K T P T K
Sbjct: 291 TPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTK---S 347
Query: 324 VPPPPVAPAPSPLAPPLP 341
P P PAP+ P P
Sbjct: 348 APTTPKEPAPTTTKEPAP 365
Score = 35.8 bits (81), Expect = 0.12
Identities = 59/296 (19%), Positives = 93/296 (31%), Gaps = 73/296 (24%)
Query: 145 NHSETPAAPALPPSAPPKPRPKPKPKKSPVPP---------------------------- 176
N + P++ PP + K K+SP PP
Sbjct: 68 NPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSS 127
Query: 177 ---------------KGATAGASHKGDEVPPIKKNTKAPGKQAPVPPPKPAS-------- 213
+ A+ + + +K N K K+ P P P
Sbjct: 128 SSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDN 187
Query: 214 ---RNTTREAAGSSHSKKTTGSKASASPSTSSTSSRP---KASKET-VSSKAGTVGTTKG 266
+ TT + + + H+K +T K + + + S P SKET ++ T TK
Sbjct: 188 GDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKE 247
Query: 267 KRKTDKQPITSHLSSDTTTSGTSDLKGEPAETRVESFK-LEQTVPGAEEQNTGKFKSMVP 325
T+KQ T T+ T ++ A+ + K L + P AE G
Sbjct: 248 TTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKG------- 300
Query: 326 PPPVAPAPSPLAPPLPLEDQCITASD-TPVVLVSVGADLPVSALDPSQLLWAEEPT 380
P P P P E T + TP + S P + +P+ PT
Sbjct: 301 --PALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA----PTTPKEPAPTTTKSAPT 350
Score = 32.7 bits (73), Expect = 1.0
Identities = 30/103 (29%), Positives = 40/103 (38%), Gaps = 9/103 (8%)
Query: 133 EEQAEDKKENTENHSETPAAPALPPSAPPKPRPKPKPKKSPVPPKGATAGASHK----GD 188
EE A+ K T + + TP P P AP KP KPK P K T K
Sbjct: 961 EETAKPKDRATNSKATTPK-PQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMP 1019
Query: 189 EVPPIKKNTKAPGKQAPVPPPKPASR----NTTREAAGSSHSK 227
E+ P + +A + P P S+ N E AG + +
Sbjct: 1020 ELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGE 1062
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 60.5 bits (145), Expect = 5e-09
Identities = 65/246 (26%), Positives = 87/246 (35%), Gaps = 27/246 (10%)
Query: 129 TPPLEEQAEDKKENTENHSETPAAPALPPSAPPKPRPKPKPKKSPVPPKGATAGASHKGD 188
T P E KE ++ PA P+ P +P P + +P PK T K
Sbjct: 579 TTPKEPAPTTPKEPAPTTTKKPA-----PTTPKEPAPTTPKETAPTTPKKLTPTTPEKLA 633
Query: 189 EVPPIKKNTKAPGKQAPVPPPKPASRN------TTREAAGSSHSKKTTGSKASASPSTSS 242
P K P + AP P +P TT +AA + K+ + T+
Sbjct: 634 PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTP 693
Query: 243 TSSRPKASKETV-SSKAGTVGTT--KGKRKTDKQPITSHLSSDTTTSGTSDLKGEPAETR 299
P KET ++ GT TT + T K+P L+ TT TS +PA T
Sbjct: 694 KEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTT 753
Query: 300 VESF------KLEQTVPGAEEQNTGK------FKSMVPPPPVAPAPSPLAPPLPLEDQCI 347
+ + T P T K K P P PAP LA P +
Sbjct: 754 PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELA-PTTTKGPTS 812
Query: 348 TASDTP 353
T SD P
Sbjct: 813 TTSDKP 818
Score = 56.6 bits (135), Expect = 7e-08
Identities = 56/198 (28%), Positives = 75/198 (37%), Gaps = 12/198 (6%)
Query: 129 TPPLEEQAEDKKENTENHSETPAAPALPPSAPPKPRPKPKPKK-SPVPPKGATAGASHKG 187
T P E KE + A L AP P+ KP PK+ +P KG T+ S K
Sbjct: 760 TTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK-KPAPKELAPTTTKGPTSTTSDKP 818
Query: 188 DEVPPIKKNTKAPGKQAPVPPPKPASRN------TTREAAGSSHSKKTTGSKASASPSTS 241
P + P + AP P KPA TT E + + +K+ T S ST
Sbjct: 819 APTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTP 878
Query: 242 STSSRPKASKETVSSKAGTVGTTKGKRKTDKQPITSHLSSDTTTSGTSDLKGEPAETRVE 301
S+ P S K V TTK T + T+ + D TT DL+ P T
Sbjct: 879 ELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTT--AKDKTTE--RDLRTTPETTTAA 934
Query: 302 SFKLEQTVPGAEEQNTGK 319
++T E+ K
Sbjct: 935 PKMTKETATTTEKTTESK 952
Score = 55.8 bits (133), Expect = 1e-07
Identities = 77/292 (26%), Positives = 105/292 (35%), Gaps = 39/292 (13%)
Query: 109 STREENVVKSEEGNGSVSEKTPPLEEQAEDKKENTENHSETPAAPALPPSAPPKPRPKPK 168
+T +E + + + K P E T++ TP PA P+ P KP P
Sbjct: 391 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPA--PTTPKKPAPTTP 448
Query: 169 PKKSPVP--PKGAT-------AGASHKGDEVPPIKKNTKAPGKQAPVPPPKPASRNTTRE 219
K P P PK T A + + P + AP K AP P +PA
Sbjct: 449 --KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEP 506
Query: 220 AAGSSHSKKTTGSKASASPSTSSTSSRPKASKETVSSKAGTVGTTKGKRKTDKQPITSHL 279
A ++ T K P+ ++T S P +KE + TTK T K+P
Sbjct: 507 APTTTKEPSPTTPK---EPAPTTTKSAPTTTKEPAPT------TTKSAPTTPKEP----- 552
Query: 280 SSDTTTSGTSDLKGEPAETRVESFKLEQTVPGAEEQNTGK------FKSMVPPPPVAPAP 333
S TT EPA T + K T P T K K P P PAP
Sbjct: 553 SPTTTKEPAPTTPKEPAPTTPK--KPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAP 610
Query: 334 SPLAPPLPLEDQCITASDTPVVLVSVGADLPVSALDPSQL--LWAEEPTNRT 383
+ P + +T + TP L + P + P +L EEPT T
Sbjct: 611 TTPKETAPTTPKKLTPT-TPEKLAPTTPEKP-APTTPEELAPTTPEEPTPTT 660
Score = 55.5 bits (132), Expect = 2e-07
Identities = 97/451 (21%), Positives = 146/451 (32%), Gaps = 45/451 (9%)
Query: 1 MDNAVDGLDKASIANSDGPTAGSQTPPFKRKGKLSTIGKIFKPWKWRKK--KTSDKFRET 58
+D A GLD + T+ +Q K++T KP R SD +ET
Sbjct: 219 VDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTA----KPINPRPSLPPNSDTSKET 274
Query: 59 SAVLERKISTRQSREELIRRGVLKELPDQDGDVTVNFENSNGHMIPIGEESTREENVVKS 118
S + ++ +T +++E K+ + T + + + ++ V+
Sbjct: 275 SLTVNKE-TTVETKETTTTN---KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK 330
Query: 119 EEGNGSVSEKTP----PLEEQAEDKKE--NTENHSETPAAPALPPSAPPKPRPKPKPKKS 172
+ K P P E KE +T TP P+ P +P P
Sbjct: 331 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 390
Query: 173 PVPPKGATAGASHKGDEVP--PIKKNTKAPG----KQAPVPPPKPA-------SRNTTRE 219
P + A P P TK P K AP P +PA + T +E
Sbjct: 391 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE 450
Query: 220 AAGSSHSKKTTGSKASASPSTSSTS-SRPKASKETVSSKAGTVGTTKGKRKTDKQ----- 273
A ++ + T + +P+T + + PK T K + T K+
Sbjct: 451 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 510
Query: 274 -----PITSHLSSDTTTSGTSDLKGEPAETRVESFKLEQTVPGAEEQNTGKFKSMVPPPP 328
P T + TTT EPA T +S T P T K + P
Sbjct: 511 TKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKS---APTTPKEPSPTTTKEPAPTTPKE 567
Query: 329 VAP-APSPLAPPLPLEDQCITASD-TPVVLVSVGADLPVSALDPSQLLWAEEPTNRTTLY 386
AP P AP P E T + P P + A + T
Sbjct: 568 PAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPT 627
Query: 387 SGTGLSVNRENAKCFTTKEELGKTVPQLLTP 417
+ L+ TT EEL T P+ TP
Sbjct: 628 TPEKLAPTTPEKPAPTTPEELAPTTPEEPTP 658
Score = 53.5 bits (127), Expect = 6e-07
Identities = 73/335 (21%), Positives = 111/335 (33%), Gaps = 60/335 (17%)
Query: 129 TPPLEEQAEDKKENTENHSE-----TPAAPA------LPPSAPPKPRPKPKPKKSPVPPK 177
T P E K+ T E TP PA L P+ P +P P + +P PK
Sbjct: 611 TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPK 670
Query: 178 GATAGASHKGDEVPPIKKNTKAPGKQAPV----------------------------PPP 209
A + P + P + AP P P
Sbjct: 671 AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 730
Query: 210 KPASRNTTREAAGSSHSKKTTGSKASASPSTSSTSSRPKASKETVSSKAGTVGTT--KGK 267
K + TT+E ++ K + +P+T + + ++ GT TT +
Sbjct: 731 KELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPA 790
Query: 268 RKTDKQPITSHLSSDTTTSGTSDLKGEPAETRVESFKLEQTVPGAEEQNTGKFKSMVPPP 327
T K+P L+ TT TS +PA T ++T P K P
Sbjct: 791 PTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP-----KETAPTTP-------KEPAPTT 838
Query: 328 PVAPAPSPLAPPLPLEDQCITASDT---PVVLVSVGADLPVSALDPSQLLWAEEPTNRTT 384
P PAP+ P P + T + T + S P + +P+ P
Sbjct: 839 PKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGV 898
Query: 385 LYSGTGLSVNRE---NAKCFTTKEELGKTVPQLLT 416
+ T + E AK TT+ +L +T P+ T
Sbjct: 899 PTTKTPAATKPEMTTTAKDKTTERDL-RTTPETTT 932
Score = 52.4 bits (124), Expect = 1e-06
Identities = 79/307 (25%), Positives = 109/307 (35%), Gaps = 43/307 (14%)
Query: 126 SEKTPPLEEQAEDKKENTENHSETPAAPALPPSAPPKPR-PKPKPKKSPVPPKGATAGAS 184
S TP +E A ++ ++ PA P SAP P+ P P K P P
Sbjct: 515 SPTTP--KEPAPTTTKSAPTTTKEPA-PTTTKSAPTTPKEPSPTTTKEPAP--------- 562
Query: 185 HKGDEVPPIKKNTKAPGKQAPVPPPKPASRNTTREAAGSSHSKKTTGSKASASPSTSSTS 244
P + P K AP P +PA T +E A ++ K + +P+T +
Sbjct: 563 -----TTPKEPAPTTPKKPAPTTPKEPAP-TTPKEPAPTTTKKPAPTTPKEPAPTTPKET 616
Query: 245 SRPKASKETVSSKAGTVGTTKGKRKTDKQPITSHLSSDTTTSGTSDLKGEPAETRVESFK 304
+ K T ++ TT K P T + TT EP T E +
Sbjct: 617 APTTPKKLTPTTPEKLAPTTPEK----PAPTTPEELAPTTPE-------EPTPTTPE--E 663
Query: 305 LEQTVPGAEEQNTGKFKSMVPPPPVAP-APSPLAPPLPLEDQCITASDTPVVLVSVGADL 363
T P A NT K + P AP P AP P E T T + A
Sbjct: 664 PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT 723
Query: 364 PVSALDPSQL--LWAEEPTNRT------TLYSGTGLSVNRENAKCFTTKEELGKTVPQLL 415
P +L +EPT+ T T GT + +E A TT +E T P+
Sbjct: 724 TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAP--TTPKEPAPTTPKGT 781
Query: 416 TPGLMGE 422
P + E
Sbjct: 782 APTTLKE 788
Score = 49.7 bits (117), Expect = 8e-06
Identities = 80/350 (22%), Positives = 118/350 (33%), Gaps = 46/350 (13%)
Query: 19 PTAGSQTPPFKRKGKLSTIGKIFKPWKWRKKKTSDKFRETSAVLERKISTRQSREELIRR 78
PT +T P KG T K +P KK + K + E +T +
Sbjct: 698 PTTPKETAPTTPKGTAPTTLK--EPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 755
Query: 79 GVLKELPDQDGDVTVNFENSNGHMIPIGEESTREENVVKSEEGNGSVSEKTPPLEEQAED 138
G P + T P + T + +E + +K P E
Sbjct: 756 GTAPTTPKEPAPTTPK------EPAPTTPKGTAPTTL---KEPAPTTPKKPAPKELAPTT 806
Query: 139 KKENTENHSETPAAPALPPSAPPKPR-PKPKPKKSPVPPKGATAGASHKGDEVPPIKKNT 197
K T S+ PA +AP P+ P P K P P T + P K
Sbjct: 807 TKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEP 866
Query: 198 ----KAPGKQAPV----PPPKPASRN-------TTREAAGSSHSKKTTGSKASAS----P 238
K+P + P P PK + TT+ A + TT +
Sbjct: 867 TTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT 926
Query: 239 STSSTSSRPKASKETVSSKAGTVGTTKGKRKTDKQPITSHLSSDTTTSGTSDLKGEPAET 298
+ +T++ PK +KET ++ T TT+ K +TS + DTT + LK
Sbjct: 927 TPETTTAAPKMTKETATT---TEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAP 983
Query: 299 RVESFKLEQTVPGAEEQN----TGKFK------SMVPPPPVAPAPSPLAP 338
+V + K +T+ E N T K K P P P +P P
Sbjct: 984 KVTTTK--KTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKP 1031
Score = 47.4 bits (111), Expect = 4e-05
Identities = 56/258 (21%), Positives = 87/258 (33%), Gaps = 26/258 (10%)
Query: 107 EESTREENVVKSEEGNGSVSEKTPPLEEQAEDKKENTENHSETPAAPALPPSAPPKPRPK 166
EE T E +V +++E + S S + + +N+ + E + + + + K
Sbjct: 152 EEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKK 211
Query: 167 PKPKKSPVPPKGA-------------TAGASHKGDEVPPIKKNTKAPGKQAPVPPPKPAS 213
P PK V G+ T+ H P K + +PP S
Sbjct: 212 PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTS 271
Query: 214 RNTT----REAAGSSHSKKTTGSKASASPSTSSTSSRPKASKETVSSK--AGT----VGT 263
+ T+ +E + TT + S +TS++ S E S+K A T
Sbjct: 272 KETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP 331
Query: 264 TKGKRKTDKQPITSHLSSDTTTSGTSDLKGEPAETRVESFKLEQTVPGAEEQNTGKFKSM 323
T T K P + T T+ P E + K T P T K
Sbjct: 332 TPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTK---S 388
Query: 324 VPPPPVAPAPSPLAPPLP 341
P P PAP+ P P
Sbjct: 389 APTTPKEPAPTTTKEPAP 406
Score = 35.8 bits (81), Expect = 0.12
Identities = 59/296 (19%), Positives = 93/296 (31%), Gaps = 73/296 (24%)
Query: 145 NHSETPAAPALPPSAPPKPRPKPKPKKSPVPP---------------------------- 176
N + P++ PP + K K+SP PP
Sbjct: 109 NPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSS 168
Query: 177 ---------------KGATAGASHKGDEVPPIKKNTKAPGKQAPVPPPKPAS-------- 213
+ A+ + + +K N K K+ P P P
Sbjct: 169 SSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDN 228
Query: 214 ---RNTTREAAGSSHSKKTTGSKASASPSTSSTSSRP---KASKET-VSSKAGTVGTTKG 266
+ TT + + + H+K +T K + + + S P SKET ++ T TK
Sbjct: 229 GDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKE 288
Query: 267 KRKTDKQPITSHLSSDTTTSGTSDLKGEPAETRVESFK-LEQTVPGAEEQNTGKFKSMVP 325
T+KQ T T+ T ++ A+ + K L + P AE G
Sbjct: 289 TTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKG------- 341
Query: 326 PPPVAPAPSPLAPPLPLEDQCITASD-TPVVLVSVGADLPVSALDPSQLLWAEEPT 380
P P P P E T + TP + S P + +P+ PT
Sbjct: 342 --PALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA----PTTPKEPAPTTTKSAPT 391
Score = 32.7 bits (73), Expect = 1.0
Identities = 30/103 (29%), Positives = 40/103 (38%), Gaps = 9/103 (8%)
Query: 133 EEQAEDKKENTENHSETPAAPALPPSAPPKPRPKPKPKKSPVPPKGATAGASHK----GD 188
EE A+ K T + + TP P P AP KP KPK P K T K
Sbjct: 1002 EETAKPKDRATNSKATTPK-PQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMP 1060
Query: 189 EVPPIKKNTKAPGKQAPVPPPKPASR----NTTREAAGSSHSK 227
E+ P + +A + P P S+ N E AG + +
Sbjct: 1061 ELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGE 1103
>gi|73808090 zinc finger protein 207 isoform b [Homo sapiens]
Length = 463
Score = 60.5 bits (145), Expect = 5e-09
Identities = 55/210 (26%), Positives = 77/210 (36%), Gaps = 20/210 (9%)
Query: 150 PAAPALPPSAPPKPRPKPKPKKSP-VPPKGATAGASHKGDEVPPIKKNTKAPGKQAPVPP 208
P P +PP P P P P P +PP S P I AP P P
Sbjct: 209 PPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVS-----APGILNRPPAPTATVPAPQ 263
Query: 209 P---KPASRNTTREAAGSSHSKKTTGSKASASPSTSSTSSRPKASKETVSSKAGTVGTTK 265
P KP + + A T +++P+T++ +P T S+ A T TT
Sbjct: 264 PPVTKPLFPSAGQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQST-ASTTSTTN 322
Query: 266 GKRKTDKQPITSHLSSDTTTSGTS-------DLKGEPAETRVESFKLEQTVPGAE---EQ 315
ITS ++ TTTS TS D+ E ++ ++ PG
Sbjct: 323 STAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNP 382
Query: 316 NTGKFKSMVPPPPVAPAPSPLAPPLPLEDQ 345
G M+PP P P + PP+P Q
Sbjct: 383 PVGPIGGMMPPQPGIPQQQGMRPPMPPHGQ 412
>gi|52485606 formin-like 2 [Homo sapiens]
Length = 1092
Score = 60.1 bits (144), Expect = 6e-09
Identities = 44/179 (24%), Positives = 73/179 (40%), Gaps = 6/179 (3%)
Query: 29 KRKGKLSTIGKIFKPWKWRKKKTSDKFRETSAVLERKISTRQSREELIRRGVLKELPDQD 88
+R +L + +I+K + +E ++R+ + + EL ++G +K D
Sbjct: 429 QRNKELDVVREIYKDANTQVHTLRKMVKEKEEAIQRQSTLEKKIHELEKQGTIKIQKKGD 488
Query: 89 GDVTVNFENSNGHMIPIGEESTREENV--VKSEEGNGSVSEKTPPLEEQAEDKKENTENH 146
GD+ + ++G + +G E +V +G + PPL + D E +N
Sbjct: 489 GDIAILPVVASG-TLSMGSEVVAGNSVGPTMGAASSGPLPPPPPPLPPSS-DTPETVQNG 546
Query: 147 SETPAAPALPPSAPPKPRPKPKPKKSPVPPKGATAGASHKGDEVPPIKKNTKAPGKQAP 205
TP P PP PP P P P P P+P G A PP+ PG +P
Sbjct: 547 PVTPPMPPPPPPPPPPPPPPPPPPPPPLP--GPAAETVPAPPLAPPLPSAPPLPGTSSP 603
Score = 29.6 bits (65), Expect = 8.9
Identities = 11/17 (64%), Positives = 11/17 (64%)
Query: 325 PPPPVAPAPSPLAPPLP 341
PPPP P P P PPLP
Sbjct: 559 PPPPPPPPPPPPPPPLP 575
>gi|72256200 B-cell CLL/lymphoma 9 [Homo sapiens]
Length = 1426
Score = 60.1 bits (144), Expect = 6e-09
Identities = 75/351 (21%), Positives = 141/351 (40%), Gaps = 35/351 (9%)
Query: 130 PPLEEQAEDKKENTENHSETPAAPALPPSAPPKPRPKPKPKKSPVPPKGATAGASHKGDE 189
P L+ + ++ + + S++ +P S P+ P P S GA GA KG
Sbjct: 40 PQLDSKFSNQGKQGGSASQSQPSPCDSKSGGHTPKALPGPGGSMGLKNGAGNGAKGKGKR 99
Query: 190 VPPI------KKNTKAPGKQAPVPPPKPASRNTTREAAGSSHSKKTTGSKA--SASPSTS 241
I +++ P + + A ++++ + HS + + A S++PS
Sbjct: 100 ERSISADSFDQRDPGTPNDDSDIKECNSADHIKSQDSQHTPHSMTPSNATAPRSSTPSHG 159
Query: 242 STSSRPKASKETVSSKAGTVGTT-----------KGKRKTDKQPITSHLSSDTTTSGTSD 290
T++ + +K V +T KG+ +T ++S++ T T+
Sbjct: 160 QTTATEPTPAQKTPAKVVYVFSTEMANKAAEAVLKGQVETIVSFHIQNISNNKTERSTAP 219
Query: 291 LKGEPAETRVESFKLEQT--VPGAEEQNTGKFKSMVPPPPV-APAPSPLAPPLPLEDQCI 347
L + + R + L Q P ++QN+ + + P PP+ APAP P APP PL+ +
Sbjct: 220 LNTQISALRNDPKPLPQQPPAPANQDQNSSQNTRLQPTPPIPAPAPKPAAPPRPLDRESP 279
Query: 348 TASDTPVVLVSVGADLPVSALDPSQLLWAEEPTNRTTLYSGTGLSVNRENAKCFTTKEEL 407
+ ++ SVG+ + L P P NR G + + + K
Sbjct: 280 GVENK--LIPSVGSPASSTPLPPDGTGPNSTPNNRAVTPVSQGSNSSSADPK-------- 329
Query: 408 GKTVPQLLT--PGLMGESSESFSASEDEGHREYQANDSDSDGPILYTDDED 456
P + + P +GE+ + S + E HRE +L+ D+++
Sbjct: 330 APPPPPVSSGEPPTLGENPDGLSQEQLE-HRERSLQTLRDIQRMLFPDEKE 379
Score = 31.6 bits (70), Expect = 2.3
Identities = 66/279 (23%), Positives = 95/279 (34%), Gaps = 40/279 (14%)
Query: 89 GDVTVNFE-NSNGHMIP--IGEESTREENVVKSEEGNGSV---SEKTPPLEEQAEDKKEN 142
GDV +N SN MIP + E E ++K G + +K PL ++E
Sbjct: 718 GDVNLNVNMGSNSQMIPQKMREAGAGPEEMLKLRPGGSDMLPAQQKMVPLPFGEHPQQE- 776
Query: 143 TENHSETPAAPALPPSAPPKPRPKPKPKKSPVPPKGATAGASHKGDEVPPIKKNTKAPGK 202
+ P P LP S P + + P+ P T + + +PP+ N +
Sbjct: 777 ---YGMGPR-PFLPMSQGPGSNSGLRNLREPIGPDQRT---NSRLSHMPPLPLNPSSNPT 829
Query: 203 QAPVPPPKPASRNTTRE-----AAGSS-HSKKTTGSKASA-----SPSTSSTSSRPKASK 251
PP R R+ AGS HS K+ SP S S K S
Sbjct: 830 SLNTAPP--VQRGLGRKPLDISVAGSQVHSPGINPLKSPTMHQVQSPMLGSPSGNLK-SP 886
Query: 252 ETVSSKAGTVGTTKGKRKTDKQPITSHLSSDTTTSGTSDLKGEPAETRVESFKLEQTVPG 311
+T S AG + P+ ++ + L P+ S K PG
Sbjct: 887 QTPSQLAGMLAGPAAAASIKSPPVLGSAAASPVHLKSPSLPA-PSPGWTSSPKPPLQSPG 945
Query: 312 -----------AEEQNTGKFKSMVPPPPVAPAPSPLAPP 339
A G +S PPPP A P+ + P
Sbjct: 946 IPPNHKAPLTMASPAMLGNVESGGPPPPTASQPASVNIP 984
>gi|28559039 mediator complex subunit 1 [Homo sapiens]
Length = 1581
Score = 59.3 bits (142), Expect = 1e-08
Identities = 72/294 (24%), Positives = 123/294 (41%), Gaps = 58/294 (19%)
Query: 90 DVTVNFENSNGHMIPIGEESTREENVVKSEEGNGSVSE---------------KTPPLEE 134
D+ + S G ++ G+ +E+ + +EGNG+ + +TP +
Sbjct: 945 DLMEHHSGSQGPLLTTGDLG-KEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDG 1003
Query: 135 QAEDK-----KENTENHSETPAA---PALPPSAPPKPRPKPKPKKSPVPPKGATAGASHK 186
+++DK K +TE S + ++ P PP++ + +S PP AT
Sbjct: 1004 KSKDKPPKRKKADTEGKSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVAT------ 1057
Query: 187 GDEVPPIKKNT-KAPGKQAPVPPPKPASRNTTREAAGSSHSKKTTGSKASASPSTSSTSS 245
PPI K T + P V P S+ T+ + SS SK + S +S+S S++STS
Sbjct: 1058 ----PPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSK-SHHSHSSSSSSSASTSG 1112
Query: 246 RPKASKETVSSKA----------GTVGTTKGKR------KTDKQPITSHLSSDTTTSGTS 289
+ K+SK SS + G+ G+++ K K PIT H S ++S
Sbjct: 1113 KMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKM 1172
Query: 290 DLKGEPAETRVESFK------LEQTVPGAEEQNTGKFKSMVPPPPVAPAPSPLA 337
+G+P+ S PG ++ K + PP + A SP++
Sbjct: 1173 KPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPIS 1226
Score = 39.3 bits (90), Expect = 0.011
Identities = 50/228 (21%), Positives = 83/228 (36%), Gaps = 27/228 (11%)
Query: 89 GDVTVNFENSNGHMIPIGEESTREENVVKSEEGNGSVSEK--TPPLEEQAEDKKENTENH 146
G V+ + S+ S +KS + GS S K + Q ++N
Sbjct: 1087 GSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNS 1146
Query: 147 SETPAAPALPP---------SAPPKPRPKPKPKKSPVPPKGATAGASHKGDEVPPIKKNT 197
S++ P P S+ K +P+ KP S + P + S P
Sbjct: 1147 SQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPS-SLMNPSLSKPNISPSHSRPPGGSDKL 1205
Query: 198 KAPGKQAPVPPPKPAS--RNTTREAAGSSHSKKTT-----------GSKASASPSTSSTS 244
+P K PVP P+S ++ +G SH T+ GS S S T +S
Sbjct: 1206 ASPMK--PVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPSS 1263
Query: 245 SRPKASKETVSSKAGTVGTTKGKRKTDKQPITSHLSSDTTTSGTSDLK 292
+ AS + SS ++ +++ + + K S + T+ LK
Sbjct: 1264 NSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLK 1311
Score = 32.0 bits (71), Expect = 1.8
Identities = 41/197 (20%), Positives = 74/197 (37%), Gaps = 34/197 (17%)
Query: 98 SNGHMIPIGEESTREENVVKSEEGNGSVSEKTPPLEEQAEDKKENTENHSETPAAPALPP 157
S+G + G +S + S + S K+ E + K ++ S+ + +
Sbjct: 1085 SSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSK 1144
Query: 158 SAPPKPRPKPKPKKSPVPPKGATAGASHKGDEVPPIKKNTKAPGKQAPVPPPKPASRNTT 217
++ + KP SP+ G ++G+S K GK + + P + N +
Sbjct: 1145 NSS---QSGGKPGSSPITKHGLSSGSS---------STKMKPQGKPSSLMNPSLSKPNIS 1192
Query: 218 REAAGSSHSKKTTGSKASASPSTSSTSSRPKA-SKETVSSKAGTVGTTKGKRKTDKQPIT 276
SHS+ GS ASP + P + +K +SS +G
Sbjct: 1193 -----PSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSG----------------G 1231
Query: 277 SHLSSDTTTSGTSDLKG 293
SH+S +++SG G
Sbjct: 1232 SHMSGTSSSSGMKSSSG 1248
Score = 32.0 bits (71), Expect = 1.8
Identities = 41/173 (23%), Positives = 62/173 (35%), Gaps = 35/173 (20%)
Query: 110 TREENVVKSEEG---NGSVSEKTPPLEEQ--AEDKKENTENHSETPAAPALPPSAPPKPR 164
T + +KS G +GS+S+KTPP A ++ S + + S P
Sbjct: 1237 TSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPS 1296
Query: 165 PKPKPKKSPVPPKGATAGASHKGDEVPPIKKN--TKAPGKQAPVPPPKPASRNTTREAAG 222
KP + V K +K T PG + P+ S N++
Sbjct: 1297 RNKKPSLTAVIDK---------------LKHGVVTSGPGGEDPLDGQMGVSTNSSSHPMS 1341
Query: 223 SSHS----------KKTTGSKASASPSTSSTSSRPKASKETVSSKAGTVGTTK 265
S H+ +K+ K+ S S SS S K S+ S G+ G K
Sbjct: 1342 SKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSE---SKNVGSTGVAK 1391
>gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax
homolog 2 [Homo sapiens]
Length = 1210
Score = 58.5 bits (140), Expect = 2e-08
Identities = 66/256 (25%), Positives = 109/256 (42%), Gaps = 35/256 (13%)
Query: 98 SNGHMIPIGEESTREENVVKSEEGNGSVS--EKTPPLEEQAEDKKENTENHSETP--AAP 153
++ H EST + + E S S E+ PLE A + + T N +
Sbjct: 462 ASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTK 521
Query: 154 ALPPSAPPK-PRPKPKPKKSPVPPKGATAGAS---HKGDEVPPIKKNTKAPGKQAPVPPP 209
P+APP+ PR P++ P KG++ A+ H + PP K ++KAP +AP P
Sbjct: 522 VSQPAAPPEGPRSTEPPRRHP-ESKGSSDSATSQEHSESKDPPPKSSSKAP--RAPPEAP 578
Query: 210 KPASRNTTREAAGSS-HSKKTTGSKASASPSTSSTSSRPKASKETVSSKAGTVGTTKGKR 268
P R+ + A ++T G+K P + S++AG+ + +G+R
Sbjct: 579 HPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKA-------------SARAGSRTSLQGER 625
Query: 269 KTDKQPITSHLSSDTTTSGTSDLKGEPAETRVESFKLEQTVPGAEEQNTGKFKSMVPPPP 328
+ P + S D T+ +K + S + + VP + E+ K KS +P P
Sbjct: 626 EPGLLP---YGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKK--KHKSSLPAPS 680
Query: 329 VAPAPSPLAPPLPLED 344
A L+ P P +D
Sbjct: 681 KA-----LSGPEPAKD 691
Score = 40.4 bits (93), Expect = 0.005
Identities = 58/262 (22%), Positives = 79/262 (30%), Gaps = 51/262 (19%)
Query: 118 SEEGNGSVSEKTPPLEEQAEDKKENTENHSETPAAPALPPSAPPKP--------RPKPKP 169
S++G S+ E L + + E T + +AP P + P+P
Sbjct: 415 SQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESEST 474
Query: 170 KKSPVPPKGATAGASHKGDEVPPIKKNTKAPGKQAP------------------VPPPKP 211
S + +S +E P++ T AP + P PP P
Sbjct: 475 SDSDSSSDSESESSSSDSEENEPLE--TPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGP 532
Query: 212 ASRNTTR---EAAGSSHSKKTTGSKASASPSTSSTSSRPKASKETVSSKAGTVGTTKGKR 268
S R E+ GSS S + S P S+S P+A E GKR
Sbjct: 533 RSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPE---------APHPGKR 583
Query: 269 KTDKQPITSHLSSDTTTSGTSDLKGEPAETRVESFKLEQ------TVPGAEEQNTGKFKS 322
K P T K A R S Q +P T K K
Sbjct: 584 SCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKP 643
Query: 323 MV-----PPPPVAPAPSPLAPP 339
V P + P P PP
Sbjct: 644 KVKTKGRPRAAASNEPKPAVPP 665
Score = 36.6 bits (83), Expect = 0.073
Identities = 53/268 (19%), Positives = 98/268 (36%), Gaps = 46/268 (17%)
Query: 102 MIPIG--EESTREENVVKSE-EGNGSVSEKTPPLEEQAEDKKENTENHSETPAAPALPPS 158
++P G +++++++ VK++ + S + P + +KK+ H + AP+ S
Sbjct: 629 LLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKK----HKSSLPAPSKALS 684
Query: 159 APPKPRPKPK---PKKSPVPPKGATAGASHKG--------------------DEVPPIKK 195
P + + P+ + P + G H G D +P +
Sbjct: 685 GPEPAKDNVEDRTPEHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLR 744
Query: 196 NTKAPGKQAPVPPPKPASRNTTREAAGSSHSKKTTGSKASAS----PSTSSTSSRPKASK 251
+TK PPP+ T + GS+ + P S K S
Sbjct: 745 DTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSS 804
Query: 252 ETVSSKAGTVGTTKGKRKTDKQPITSHLSSDTTTSGTSDLKGEPAETRVESFKLEQTVPG 311
++ SSK + +R D + I + +S +S E ++T+ P
Sbjct: 805 DS-SSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTK----------PS 853
Query: 312 AEEQNTGKFKSMVPPPPVAPAPSPLAPP 339
+ K K M+PPPPV+ + A P
Sbjct: 854 RPSSQSSK-KEMLPPPPVSSSSQKPAKP 880
Score = 36.2 bits (82), Expect = 0.095
Identities = 36/144 (25%), Positives = 56/144 (38%), Gaps = 14/144 (9%)
Query: 111 REENVVKSEEGNGSVSEKTPPLEEQAEDKKENTENHSETPAAPALPPSAPPKPRPKPKPK 170
R E +KS+ + S S K K + + S++ LPP PP KP
Sbjct: 828 RLEKEIKSQSSSSSSSHKE-------SSKTKPSRPSSQSSKKEMLPP--PPVSSSSQKPA 878
Query: 171 KSPVPPKGATAGASHKGDEVPPIKKNTKAPGKQAPVPPPKPASRNTTREAAGSSHSKKTT 230
K + K + A G + P +TK+ K + +P + +R SS K ++
Sbjct: 879 KPAL--KRSRREADTCGQDPPKSASSTKSNHKDSSIPKQRRVEGKGSR---SSSEHKGSS 933
Query: 231 GSKASASPSTSSTSSRPKASKETV 254
G A+ P S + K K V
Sbjct: 934 GDTANPFPVPSLPNGNSKPGKPQV 957
>gi|148612835 zinc finger protein 207 isoform c [Homo sapiens]
Length = 494
Score = 58.2 bits (139), Expect = 2e-08
Identities = 59/235 (25%), Positives = 79/235 (33%), Gaps = 39/235 (16%)
Query: 150 PAAPALPPSAPPKPRPKPKPKKSP-VPPKGATAGASHKGDEVPPIKKNTKAPGKQAPVPP 208
P P +PP P P P P P +PP S G P P Q PV
Sbjct: 209 PPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTK 268
Query: 209 PKPASRN-----TTREAAGSSHSKKTTGSKASASPSTSST---------------SSRPK 248
P S T + SS+S+ + S + PST+ +S P
Sbjct: 269 PLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPVGTDFKPLNSTPA 328
Query: 249 ASKET--------VSSKAGTVGTTKGKRKTDKQPITSHLSSDTTTSGTS-------DLKG 293
+ E S A T TT ITS ++ TTTS TS D+
Sbjct: 329 TTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISL 388
Query: 294 EPAETRVESFKLEQTVPGAE---EQNTGKFKSMVPPPPVAPAPSPLAPPLPLEDQ 345
E ++ ++ PG G M+PP P P + PP+P Q
Sbjct: 389 EERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPPHGQ 443
>gi|4508017 zinc finger protein 207 isoform a [Homo sapiens]
Length = 478
Score = 58.2 bits (139), Expect = 2e-08
Identities = 59/235 (25%), Positives = 79/235 (33%), Gaps = 39/235 (16%)
Query: 150 PAAPALPPSAPPKPRPKPKPKKSP-VPPKGATAGASHKGDEVPPIKKNTKAPGKQAPVPP 208
P P +PP P P P P P +PP S G P P Q PV
Sbjct: 193 PPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTK 252
Query: 209 PKPASRN-----TTREAAGSSHSKKTTGSKASASPSTSST---------------SSRPK 248
P S T + SS+S+ + S + PST+ +S P
Sbjct: 253 PLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPVGTDFKPLNSTPA 312
Query: 249 ASKET--------VSSKAGTVGTTKGKRKTDKQPITSHLSSDTTTSGTS-------DLKG 293
+ E S A T TT ITS ++ TTTS TS D+
Sbjct: 313 TTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISL 372
Query: 294 EPAETRVESFKLEQTVPGAE---EQNTGKFKSMVPPPPVAPAPSPLAPPLPLEDQ 345
E ++ ++ PG G M+PP P P + PP+P Q
Sbjct: 373 EERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPPHGQ 427
>gi|238624188 diffuse panbronchiolitis critical region 1 protein
[Homo sapiens]
Length = 1393
Score = 56.6 bits (135), Expect = 7e-08
Identities = 89/378 (23%), Positives = 145/378 (38%), Gaps = 47/378 (12%)
Query: 97 NSNGHMIPIGEESTRE----ENVV-----KSEEGNGSVSEKTPPLEEQAEDKKENTENHS 147
N N P G RE EN +E G + +E T P + + E T N +
Sbjct: 332 NENTAPFPAGPTENREMTANENTTLFPAEPTEHGERTANENTTPSPAEPTEHGERTANEN 391
Query: 148 ETPAAPALPPSAPPKPRPKPKPKKSPVPPKGATAGASHKGDEVPPIKKNTKAPGKQAPVP 207
TP+ PA P+ + P K + ++A ++ G+ P +NT +
Sbjct: 392 TTPS-PA-EPTEHGERTPFANDKTT-----SSSAESTEHGERTPLANENTTPSPAEPTEN 444
Query: 208 PPKPASRNTTREAAGSSHSKKTTGS-KASASPSTSSTSSRPKASKETVSSKAGTVGTTKG 266
+ A+ NTT AG + +++TT + K + SP + + A+++T S A T G
Sbjct: 445 RERTANENTTPSPAGPTENRETTANEKTTLSPVEPTENRETTANEKTTPSPAEP--TENG 502
Query: 267 KRKTDKQPITSHLSSDTTTSG---------TSDLKGEPAETRVESFKLEQTVPGAEEQNT 317
+R T+ S++ T G T+ EP E R E E+T P E
Sbjct: 503 QRTPFANEKTTSSSAEPTEHGERTPLANENTTPSPAEPTENR-ERTANEKTTPSPAEPTE 561
Query: 318 GKFKSMVPPPPVAPAPSPLAPPLPLEDQCITASDTPVVLVSVGADLPVSALDPSQLLWAE 377
++ + P+ LA P + A++ S+ +P++
Sbjct: 562 NGDRTPLANEKTTPS---LAEPTENGQRTPFANEKTT----------SSSAEPTEHEERT 608
Query: 378 EPTNRTTLYSGTGLSVNRE-NAKCFTTKEELGKTVPQLLTPGLMGESSESFSASEDEGHR 436
N T S + NRE A TT G T + +T E + F A E +R
Sbjct: 609 PLANENTTPSPAEPTENRERTANENTTPSPAGPTENREMT---ANEKTTLFPAEPTE-NR 664
Query: 437 EYQANDSDSDGPILYTDD 454
E AN+ + P T++
Sbjct: 665 ERTANEKTTSSPAEPTEN 682
Score = 52.0 bits (123), Expect = 2e-06
Identities = 86/423 (20%), Positives = 149/423 (35%), Gaps = 56/423 (13%)
Query: 99 NGHMIPIGEESTREENV--VKSEEGNGSVSEKTPPLEEQAEDKKENTENHSETPAAPALP 156
NG P E T + + EE +E T P + + +E T N + TP+
Sbjct: 583 NGQRTPFANEKTTSSSAEPTEHEERTPLANENTTPSPAEPTENRERTANENTTPS----- 637
Query: 157 PSAPPKPRPKPKPKKSPVPPKGATAGASHKGDEVPPIKKNTKAP------GKQAPVPPPK 210
P+ P + R +K+ + P T +E K T +P G++ P K
Sbjct: 638 PAGPTENREMTANEKTTLFPAEPTENRERTANE-----KTTSSPAEPTENGQRTPFANEK 692
Query: 211 PASRNTTREAAGS-----------SHSKKTTGSKASASPSTSSTSSRPKASKETVSSKAG 259
S + G S ++ T + +A+ T+ + P ++E +++
Sbjct: 693 TTSSSAEPTEHGERTPLANENTTLSPAEPTENRERTANEKTTPFPAEPTENRERTANENT 752
Query: 260 TVGTTKGKRKTDKQPITSHLSSDTTTSGTSDLKGEP-AETRVESFKLEQTVPGAEEQNTG 318
T + D+ P+ + ++ + T + K P A + S E T
Sbjct: 753 TPSPAQPTENGDRTPLANEKTTPSLAEPTENGKRTPFANEKTTSSSAEPTEHAERTPLAN 812
Query: 319 KFKSMVPPPPV------APAPSPLAPPLPLEDQCITASDTPVVLVSVGADLPVSALDPSQ 372
+ + P P A + P P E++ TA++ + + + +
Sbjct: 813 ENTTSSPAEPTENRERTANEKTTQFPAEPTENRESTANEKTTPFPAEPTENREWTANENT 872
Query: 373 LLWAEEPT---------NRTTLYSGTGLSVNRENAKCFTTKEELGKTVPQLLTPGLMGES 423
L EPT N T S + N E FT + KT P P GE
Sbjct: 873 TLSPAEPTEHEEMTPLANEKTTLSPAEPTENGERTP-FTNE----KTTPSSAEPTEHGER 927
Query: 424 SE------SFSASEDEGHREYQANDSDSDGPILYTDDEDEDEDEDGSGESALASKIRRRD 477
+ + S +E H E AN+ + P T+ + +ED + SA ++ R
Sbjct: 928 TPLANEITTPSRAEPTEHGERIANEKATPSPAKPTEHGETTVNEDTTPSSAEPTENGERT 987
Query: 478 TLA 480
LA
Sbjct: 988 PLA 990
Score = 50.1 bits (118), Expect = 6e-06
Identities = 82/390 (21%), Positives = 145/390 (37%), Gaps = 63/390 (16%)
Query: 99 NGHMIPIGEESTREENVVKSEEGNGSVSEKTPPLEEQAEDKKENTENHSETPAAPALP-- 156
+G P+ E+T +E + +EKT P + + +E T N + TP +PA P
Sbjct: 703 HGERTPLANENTTLSPAEPTENRERTANEKTTPFPAEPTENRERTANENTTP-SPAQPTE 761
Query: 157 ----------PSAPPKPRPKPKPKKSPVPPKGATAGA---SHKGDEVPPIKKNTKAPGKQ 203
+ P P K++P + T+ + + + P +NT +
Sbjct: 762 NGDRTPLANEKTTPSLAEPTENGKRTPFANEKTTSSSAEPTEHAERTPLANENTTS---- 817
Query: 204 APVPPPKPASRNTTREAAGSSHSKKTTGSKASASPSTSSTSSRPKASKETVSSKAGTVGT 263
+P P + R T E ++ T +++A+ T+ + P ++E +++ T+
Sbjct: 818 SPAEPTENRER-TANEKTTQFPAEPTENRESTANEKTTPFPAEPTENREWTANENTTLSP 876
Query: 264 TKGKRKTDKQPITSHLSSDTTTSGTSDLKGEPAETRVES-FKLEQTVPGAEE-----QNT 317
+ T+ + +T + TT S EP E + F E+T P + E + T
Sbjct: 877 AE---PTEHEEMTPLANEKTTLS-----PAEPTENGERTPFTNEKTTPSSAEPTEHGERT 928
Query: 318 GKFKSMVPPPPVAPA------PSPLAPPLPLEDQCITASDTPVVLVSVGADLPVSALDPS 371
+ P P + A P P A T +V D S+ +P+
Sbjct: 929 PLANEITTPSRAEPTEHGERIANEKATPSP-------AKPTEHGETTVNEDTTPSSAEPT 981
Query: 372 QLLWAEEPTNRTTLYSGTGLSVNRENAKCFTTKEELGKTVPQLLTPGLMGESSESF---- 427
+ N T S T + + E T E KT P P GE + S
Sbjct: 982 ENGERTPLANENTTTSPTESTEHGER----TANE---KTTPSPAEPTEHGERTPSANEKT 1034
Query: 428 --SASEDEGHREY--QANDSDSDGPILYTD 453
S ++ H E AN++ + P+ T+
Sbjct: 1035 IPSPAKPTEHEEMTPSANENTTPSPVKPTE 1064
Score = 49.3 bits (116), Expect = 1e-05
Identities = 61/282 (21%), Positives = 105/282 (37%), Gaps = 57/282 (20%)
Query: 85 PDQDGDVTVNFENS--------NGHMIPIGEESTREENVVKSEEGNGSVSEKTPPLEEQA 136
P + G+ TVN + + NG P+ E+T +E G + +EKT P +
Sbjct: 961 PTEHGETTVNEDTTPSSAEPTENGERTPLANENTTTSPTESTEHGERTANEKTTPSPAEP 1020
Query: 137 EDKKENTENHSE----TPAAPA----LPPSAPPKPRPKP-KP-----------KKSPVPP 176
+ E T + +E +PA P + PSA P P KP +K + P
Sbjct: 1021 TEHGERTPSANEKTIPSPAKPTEHEEMTPSANENTTPSPVKPTEHGEKTTLANEKITLSP 1080
Query: 177 KGAT---AGASHKGDEVPPIKKNTKAPGKQAPVPPPK----PASRNTTREAAGSS----- 224
+G T A + +++ P G++ P K A R+ A S+
Sbjct: 1081 EGPTEHGAKTTSANEKITPSLAKPTEHGERTTSPNDKITSSAAESTEHRDRATSANVITP 1140
Query: 225 -------HSKKTTGSKASASPSTSSTSSRPKASKETVSSKAGT----------VGTTKGK 267
H+K+TT + + T ++ P+ + T T TKGK
Sbjct: 1141 APAEPIKHAKRTTLAHEKMTQVTEKSTEHPEKTTSTTEKTTRTPEKPTLYSEKTICTKGK 1200
Query: 268 RKTDKQPITSHLSSDTTTSGTSDLKGEPAETRVESFKLEQTV 309
+ T +L + T T+ T + E ++ + +T+
Sbjct: 1201 NTPVPEKPTENLGNTTLTTETIKAPVKSTENPEKTAAVTKTI 1242
Score = 48.5 bits (114), Expect = 2e-05
Identities = 74/369 (20%), Positives = 131/369 (35%), Gaps = 38/369 (10%)
Query: 107 EESTREENVVKSEEGNGSVSEKTPPLEEQAE-DKKENTENHSETPAAPALPPSAPPKPRP 165
+ ST + E N S K P + Q D ++T H E+ + P+ P+
Sbjct: 109 KSSTDNHEAPPTSEENSSNQGKDPMIRNQRSVDPADSTTTHKESAGKKHITPA----PKS 164
Query: 166 KPKPKKSPVPPKGATAGASHKGDEVPPIKKNTKAPGKQAPVPPPKPASRNTTREAAGSSH 225
K +KS T G S + + + G+ P S +T + + SSH
Sbjct: 165 KINCRKS-------TTGKS-------TVTRKSDKTGR------PLEKSMSTLDKTSTSSH 204
Query: 226 SKKTTGSKASASPSTSSTSSRPKASKETVSSKAGTVGTTKGKRKTDKQPITSHLSSDTTT 285
T+ + S + ++S P+ + T GT + KT+ T+ S T
Sbjct: 205 KTTTSFHNSGNSQTKQKSTSFPEKITAASKTTYKTTGTPEESEKTEDSR-TTVASDKLLT 263
Query: 286 SGTSDLKGEPAETRVESFKLEQTVPGAEEQNTGKFKSMVPPPP----VAPAPSPLAPPLP 341
T +++ + + E T G N S P A + L+P P
Sbjct: 264 KTTKNIQETISANELTQSLAEPTEHGGRTANENNTPSPAEPTENRERTANENTTLSPAEP 323
Query: 342 LEDQCITASDTPVVLVSVGADLPVSALDPSQLLWAEEPT--------NRTTLYSGTGLSV 393
+E++ TA++ + + + + L+ EPT TT
Sbjct: 324 IENRERTANENTAPFPAGPTENREMTANENTTLFPAEPTEHGERTANENTTPSPAEPTEH 383
Query: 394 NRENAKCFTTKEELGKTVPQLLTPGLMGESSESFSASEDEGHREYQANDSDSDGPILYTD 453
A TT T TP +++ S + S + G R AN++ + P T+
Sbjct: 384 GERTANENTTPSPAEPTEHGERTPFANDKTTSSSAESTEHGERTPLANENTTPSPAEPTE 443
Query: 454 DEDEDEDED 462
+ + +E+
Sbjct: 444 NRERTANEN 452
>gi|239740773 PREDICTED: similar to diffuse panbronchiolitis
critical region 1 [Homo sapiens]
Length = 1400
Score = 56.6 bits (135), Expect = 7e-08
Identities = 89/378 (23%), Positives = 145/378 (38%), Gaps = 47/378 (12%)
Query: 97 NSNGHMIPIGEESTRE----ENVV-----KSEEGNGSVSEKTPPLEEQAEDKKENTENHS 147
N N P G RE EN +E G + +E T P + + E T N +
Sbjct: 394 NENTAPFPAGPTENREMTANENTTLFPAEPTEHGERTANENTTPSPAEPTEHGERTANEN 453
Query: 148 ETPAAPALPPSAPPKPRPKPKPKKSPVPPKGATAGASHKGDEVPPIKKNTKAPGKQAPVP 207
TP+ PA P+ + P K + ++A ++ G+ P +NT +
Sbjct: 454 TTPS-PA-EPTEHGERTPFANDKTT-----SSSAESTEHGERTPLANENTTPSPAEPTEN 506
Query: 208 PPKPASRNTTREAAGSSHSKKTTGS-KASASPSTSSTSSRPKASKETVSSKAGTVGTTKG 266
+ A+ NTT AG + +++TT + K + SP + + A+++T S A T G
Sbjct: 507 RERTANENTTPSPAGPTENRETTANEKTTLSPVEPTENRETTANEKTTPSPAEP--TENG 564
Query: 267 KRKTDKQPITSHLSSDTTTSG---------TSDLKGEPAETRVESFKLEQTVPGAEEQNT 317
+R T+ S++ T G T+ EP E R E E+T P E
Sbjct: 565 QRTPFANEKTTSSSAEPTEHGERTPLANENTTPSPAEPTENR-ERTANEKTTPSPAEPTE 623
Query: 318 GKFKSMVPPPPVAPAPSPLAPPLPLEDQCITASDTPVVLVSVGADLPVSALDPSQLLWAE 377
++ + P+ LA P + A++ S+ +P++
Sbjct: 624 NGDRTPLANEKTTPS---LAEPTENGQRTPFANEKTT----------SSSAEPTEHEERT 670
Query: 378 EPTNRTTLYSGTGLSVNRE-NAKCFTTKEELGKTVPQLLTPGLMGESSESFSASEDEGHR 436
N T S + NRE A TT G T + +T E + F A E +R
Sbjct: 671 PLANENTTPSPAEPTENRERTANENTTPSPAGPTENREMT---ANEKTTLFPAEPTE-NR 726
Query: 437 EYQANDSDSDGPILYTDD 454
E AN+ + P T++
Sbjct: 727 ERTANEKTTSSPAEPTEN 744
Score = 47.4 bits (111), Expect = 4e-05
Identities = 74/369 (20%), Positives = 130/369 (35%), Gaps = 38/369 (10%)
Query: 107 EESTREENVVKSEEGNGSVSEKTPPLEEQAE-DKKENTENHSETPAAPALPPSAPPKPRP 165
+ ST + E N S K P + Q D ++T H E+ + P+ P+
Sbjct: 171 KSSTDNHEAPPTSEENSSNQGKDPMIRNQRSVDPADSTTTHKESAGKKHITPA----PKS 226
Query: 166 KPKPKKSPVPPKGATAGASHKGDEVPPIKKNTKAPGKQAPVPPPKPASRNTTREAAGSSH 225
K +KS T G S + + + G+ P S +T + + SSH
Sbjct: 227 KINCRKS-------TTGKS-------TVTRKSDKTGR------PLEKSMSTLDKTSTSSH 266
Query: 226 SKKTTGSKASASPSTSSTSSRPKASKETVSSKAGTVGTTKGKRKTDKQPITSHLSSDTTT 285
T+ + S + ++S P+ + T GT + KT+ T+ S T
Sbjct: 267 KTTTSFHNSGNSQTKQKSTSFPEKITAASKTTYKTTGTPEESEKTEDSR-TTVASDKLLT 325
Query: 286 SGTSDLKGEPAETRVESFKLEQTVPGAEEQNTGKFKSMVPPPP----VAPAPSPLAPPLP 341
T +++ + + E T G N S P A + L+P P
Sbjct: 326 KTTKNIQETISANELTQSLAEPTEHGGRTANENNTPSPAEPTENRERTANENTTLSPAEP 385
Query: 342 LEDQCITASDTPVVLVSVGADLPVSALDPSQLLWAEEPT--------NRTTLYSGTGLSV 393
E++ TA++ + + + + L+ EPT TT
Sbjct: 386 TENRERTANENTAPFPAGPTENREMTANENTTLFPAEPTEHGERTANENTTPSPAEPTEH 445
Query: 394 NRENAKCFTTKEELGKTVPQLLTPGLMGESSESFSASEDEGHREYQANDSDSDGPILYTD 453
A TT T TP +++ S + S + G R AN++ + P T+
Sbjct: 446 GERTANENTTPSPAEPTEHGERTPFANDKTTSSSAESTEHGERTPLANENTTPSPAEPTE 505
Query: 454 DEDEDEDED 462
+ + +E+
Sbjct: 506 NRERTANEN 514
Score = 44.3 bits (103), Expect = 3e-04
Identities = 37/192 (19%), Positives = 77/192 (40%), Gaps = 21/192 (10%)
Query: 99 NGHMIPIGEESTREENVVKSEEGNGSVSEKTPPLEEQAEDKKENTENHSETPAAPALP-- 156
+G P+ E+T +E + +EKT P + + +E T N + TP +PA P
Sbjct: 765 HGERTPLANENTTLSPAGPTENRERTANEKTTPFPAEPTENRERTANENTTP-SPAQPTE 823
Query: 157 ----------PSAPPKPRPKPKPKKSPVPPKGATAGA---SHKGDEVPPIKKNTKAPGKQ 203
+ P P K++P + T+ + + + P +NT +
Sbjct: 824 NGDRTPLANEKTTPSLAEPTENGKRTPFANEKTTSSSAEPTEHAERTPLANENTTS---- 879
Query: 204 APVPPPKPASRNTTREAAGSSHSKKTTGSKASASPSTSSTSSRPKASKETVSSKAGTVGT 263
+P P + R T E ++ T +++A+ T+ + P ++E +++ T+
Sbjct: 880 SPAEPTENRER-TANEKTTQFPAEPTENRESTANEKTTPFPAEPTENREWTANENTTLSP 938
Query: 264 TKGKRKTDKQPI 275
+ + P+
Sbjct: 939 AEPTEHEEMTPL 950
Score = 35.0 bits (79), Expect = 0.21
Identities = 56/268 (20%), Positives = 94/268 (35%), Gaps = 32/268 (11%)
Query: 103 IPIGEESTREENVVKSEEGNGSVSEKTPPLEEQAEDKKENTENHSETPAAPALPPSAPPK 162
+P ++ +N E ++SE T +ED +T+ + AA ++P +A
Sbjct: 1068 VPTTASTSGSKNTTACE---ATMSETTIAAITASEDTTVSTQ--TSVIAAESVPHTATKT 1122
Query: 163 PRPKPKPKKSPVPPKGATAGASHKGDEVPP----------IKKNTKAPGKQAPVPPPKPA 212
P S PK T P K T + P
Sbjct: 1123 PTDTTTASVSATVPKNNTLSVITSTPSTAPNTASKTMTTASKTTTTSTITSLPTTVFTTT 1182
Query: 213 SRNT---------TREAAGSSHSKKTTGSKASASPSTSSTSSRPKASKETVSSKAGTVGT 263
S+ T T ++A ++ S K +G+ ++PST+ P ET ++ T +
Sbjct: 1183 SKITAGSEIPTASTTDSATTAISTKASGTTVESAPSTA-----PPTPAETTTASVPTTTS 1237
Query: 264 TKGKRKTDKQPITSHLSSDTTTSGTSDLKGEPAETRVESFKLEQTVPGAEEQNTGKFKSM 323
T G T ++S ++ T+ S E TR + E T TG ++
Sbjct: 1238 TTGSENTGHHTVSSVPTTVFATASESSTGSE--TTRASTSATEVTTAMTTAMTTGSETAV 1295
Query: 324 V-PPPPVAPAPSPLAPPLPLEDQCITAS 350
V PV S + + + TAS
Sbjct: 1296 VSTKAPVTTTQSGFSTATVMPAKTTTAS 1323
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 56.6 bits (135), Expect = 7e-08
Identities = 55/212 (25%), Positives = 77/212 (36%), Gaps = 40/212 (18%)
Query: 153 PALPPSAPPKPRPKPKPKKSPVPPKGATAGASHKGDEVPPIKKNTKAPGKQAPVPPPKPA 212
P PPS P P P P P SP P K + G KK +K PPP P
Sbjct: 928 PPPPPSPVPAPPPPPPPTASPTPDKSGSPG-----------KKTSKTSSPGGKKPPPTPQ 976
Query: 213 SRNTTREAAGSSHSK-----------KTTGSKASASPSTSS---TSSRPKASKETVSSKA 258
++ + ++G+ H + K T S SPS + ++ PK K +S
Sbjct: 977 RNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSG-V 1035
Query: 259 GTVGTTKGKRKTDKQPITSHLSSDTTTS-----GTSDLKGEPAETRVESFKLEQTVPGAE 313
G + + K P+ S D+ SD P ET + +E +P
Sbjct: 1036 NLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIE--IPAVF 1093
Query: 314 EQNTGKFKSMVPPPP-------VAPAPSPLAP 338
NT ++V P P V AP P P
Sbjct: 1094 SGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRP 1125
Score = 54.7 bits (130), Expect = 3e-07
Identities = 58/210 (27%), Positives = 79/210 (37%), Gaps = 32/210 (15%)
Query: 150 PAAPA-LPPSAPPKPR---PKPKPKKSPVPPKGATAGASHKGDEVPPIKKNTKAPGKQAP 205
P PA LPP APPKP P P K+ V P A VPP KK P P
Sbjct: 767 PPIPAPLPPQAPPKPLVTIPAPTSTKT-VAPVVTQAAPPTPTPPVPPAKKQPAFPASYIP 825
Query: 206 VPPPKPASRNTTREAAGSSHSKKTTGSKAS--ASPSTSSTSSRPKASKETVSSKAGTVGT 263
PP P T + S A P S S P K+ ++S+ T
Sbjct: 826 PSPPTPPV----------PVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQ-IASQFPPPPT 874
Query: 264 TKGKRKTDKQPITSHLSSDTTTSGTSDLKGEPAETRVESFKLEQTVPGAEEQNTGKFKSM 323
+P+ ++++ + + + K +P+ V S P + +
Sbjct: 875 PPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESS--------LV 926
Query: 324 VPPPPVAPAPSPLAPPLPLEDQCITASDTP 353
PPPP +P P+P PP P TAS TP
Sbjct: 927 FPPPPPSPVPAPPPPPPP------TASPTP 950
Score = 46.2 bits (108), Expect = 9e-05
Identities = 67/278 (24%), Positives = 91/278 (32%), Gaps = 38/278 (13%)
Query: 112 EENVVKSEEGNGSVSEKTPPLEEQAEDKKENTENHSETPAAPALPPSAPPKPRPKPKPKK 171
E + + E N + PPL Q + T + P P PP PP P P P P
Sbjct: 589 ESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPP 648
Query: 172 SP---VPPKGATA-------------------GASHKGDEVPPIKKNTKAPGKQAP---- 205
P P G+ A GA K P ++ + P P
Sbjct: 649 LPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGV 708
Query: 206 VPPPKPASRNTTREAAGSSHSKKTTGSKASASPSTSSTSSRPKASK----ETVSSKAGTV 261
VPPP P T GS+ ++ A +PS S+ P K + ++ A
Sbjct: 709 VPPPPPPPPPPT---PGSAMAQL---KPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPT 762
Query: 262 GTTKGKRKTDKQPITSHLSSDTTTSGTSDLKGEPAETRVESFKLEQTVPGAEEQNTGKFK 321
P T + TS P T+ VP A++Q
Sbjct: 763 PPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFP-A 821
Query: 322 SMVPPPPVAPAPSPLAPPLPLEDQCITASDTPVVLVSV 359
S +PP P P P P+ PP + Q A P L V
Sbjct: 822 SYIPPSPPTP-PVPVPPPTLPKQQSFCAKPPPSPLSPV 858
Score = 41.2 bits (95), Expect = 0.003
Identities = 53/235 (22%), Positives = 79/235 (33%), Gaps = 41/235 (17%)
Query: 153 PALPPS-APPKPRPKPKPKKSPVPPKGATAGASHKGDEVPPIKKNTKAPGKQAPVPPPKP 211
PA P S PP P P P P PK + A + P+ K Q P PP P
Sbjct: 817 PAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPP 876
Query: 212 ASRNTTRE---AAGSSHSKKTTGSKASASPSTSSTSS----------------------- 245
A + + A + S +K PS+ S
Sbjct: 877 AMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVP 936
Query: 246 ----RPKASKETVSSKAGTVG--TTKGKRKTDKQPITSHLSSDTTTSGTSDLKGEPAETR 299
P + K+G+ G T+K K+P + + + S + EP
Sbjct: 937 APPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPS 996
Query: 300 VESFKLEQTVPGAEEQNTGKFKSMVPPPPVAPAP-----SPLAPPLPLEDQCITA 349
V+S + T P ++ K +PPP P P S + P L+ C++A
Sbjct: 997 VDSLVSKFTPPA---ESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSA 1048
Score = 38.1 bits (87), Expect = 0.025
Identities = 55/257 (21%), Positives = 83/257 (32%), Gaps = 31/257 (12%)
Query: 96 ENSNGHMIPIGEESTREENVVKSEEGNGSVSEKTPPLEEQAEDKKENTENHSETPAAPAL 155
++++ + G T+ V+S+ SV + Q E+ + P +
Sbjct: 547 QSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEESSKARMESMNRPYTSLV 606
Query: 156 PPSAPPKPRPKPKPKKSPVPPKGATAGASHKGDEVPPIKKNTKAPGKQAPVPPPKPASRN 215
PP +P P P PP PP P P PPP P+
Sbjct: 607 PPLSPQPKIVTPYTASQPSPPL------------PPPPPPPPPPPPPPPPPPPPLPSQSA 654
Query: 216 TTREAAGSSHSKKTTGSKASASPSTSSTSSRPKAS--KETVSSKAGTVGTTKGKRKTDKQ 273
+ +A K +T ++ + S +P ++ S K + G
Sbjct: 655 PSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPP 714
Query: 274 PITSHLSSDTTTSGTSDLKGEPAETRVESF-------KLEQTVPGAEEQNTGKFKSMVPP 326
P T S + LK P + F K+ Q + T PP
Sbjct: 715 P----PPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQV-----QHITQVAPPTPPP 765
Query: 327 PPVAPAP-SPLAPPLPL 342
PP PAP P APP PL
Sbjct: 766 PPPIPAPLPPQAPPKPL 782
Score = 37.7 bits (86), Expect = 0.033
Identities = 39/139 (28%), Positives = 53/139 (38%), Gaps = 16/139 (11%)
Query: 230 TGSKASASPSTSSTSSRPKASKETVSSKAGTVGTTKGKRKTDKQPITSHLSSDTTTSGTS 289
T +S+ S SS+SS P++ + V T+ Q I S + S+ GT
Sbjct: 527 TSLSSSSIKSGSSSSSIPESQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQ 586
Query: 290 DLKGEPAETRVESFKLEQT--VPGAEEQN------TGKFKSMV------PPPPVAPAPSP 335
E ++ R+ES T VP Q T S PPPP P P P
Sbjct: 587 --LEESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPP 644
Query: 336 LAPPLPLEDQCITASDTPV 354
PPLP + S P+
Sbjct: 645 PPPPLPSQSAPSAGSAAPM 663
Score = 34.3 bits (77), Expect = 0.36
Identities = 50/212 (23%), Positives = 83/212 (39%), Gaps = 24/212 (11%)
Query: 123 GSVSEKTPPLEEQAEDKKENTENHSETPAAPALPPSAPPKPRPKPKPKKSPVPPKGATAG 182
G VS K P L + +D + P+ PP P P P P + P G T
Sbjct: 1044 GCVSAKAPVLSGRGKD---SVVEFPSPPSDSDFPPPPPETELPLP-PIEIPAVFSGNT-- 1097
Query: 183 ASHKGDEVPPIKKN-TKAPGKQAPVPPPKPASRNTTREAAGSSHSKKTTGSKASASPSTS 241
S K V P + +K K+AP PP +P ++TR T ++ S P+ +
Sbjct: 1098 -SPKVAVVNPQPQQWSKMSVKKAP-PPTRPKRNDSTR----------LTQAEISEQPTMA 1145
Query: 242 STSSR-PKASKETVSSKAGTVG----TTKGKRKTDKQPITSHLSSDTTTSGTSDLKGEPA 296
+ + P + K ++S + G + T + K T ++S +S T+ D+ P
Sbjct: 1146 TVVPQVPTSPKSSLSVQPGFLADLNRTLQRKSITRHGSLSSRMSRAEPTATMDDMALPPP 1205
Query: 297 ETRVESFKLEQTVPGAEEQNTGKFKSMVPPPP 328
+ S + + G+ + PP P
Sbjct: 1206 PPELLSDQQKAGYGGSHISGYATLRRGPPPAP 1237
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.304 0.124 0.342
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,738,900
Number of Sequences: 37866
Number of extensions: 1761018
Number of successful extensions: 32546
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 616
Number of HSP's successfully gapped in prelim test: 1913
Number of HSP's that attempted gapping in prelim test: 13898
Number of HSP's gapped (non-prelim): 12682
length of query: 634
length of database: 18,247,518
effective HSP length: 108
effective length of query: 526
effective length of database: 14,157,990
effective search space: 7447102740
effective search space used: 7447102740
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.