Search of human proteins with 154146187

Search of human proteins with 154146187

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|154146187 TFIIS central domain-containing protein 1 [Homo
sapiens]
         (381 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|154146187 TFIIS central domain-containing protein 1 [Homo sap...   778   0.0  
gi|41350335 transcription elongation factor A (SII), 3 [Homo sap...   137   2e-32
gi|4507385 transcription elongation factor A protein 2 isoform a...   132   5e-31
gi|5803191 transcription elongation factor A 1 isoform 1 [Homo s...   128   7e-30
gi|239749424 PREDICTED: hypothetical protein XP_002347041 [Homo ...   125   8e-29
gi|38505156 transcription elongation factor A protein 2 isoform ...   122   4e-28
gi|45439355 transcription elongation factor A 1 isoform 2 [Homo ...   117   2e-26
gi|7662018 PHD finger protein 3 [Homo sapiens]                         50   3e-06
gi|47271475 SPOC domain containing 1 [Homo sapiens]                    42   7e-04
gi|28372523 intraflagellar transport protein IFT20 [Homo sapiens]      42   0.001
gi|219881538 hypothetical protein LOC199870 isoform 2 [Homo sapi...    40   0.003
gi|219881536 hypothetical protein LOC199870 isoform 1 [Homo sapi...    40   0.003
gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]       40   0.005
gi|71044477 death inducer-obliterator 1 isoform b [Homo sapiens]       40   0.005
gi|6005810 mitogen-activated protein kinase kinase kinase kinase...    40   0.005
gi|58533176 zinc finger, matrin type 1 isoform 1 [Homo sapiens]        39   0.008
gi|148839316 NIMA-related kinase 4 [Homo sapiens]                      38   0.013
gi|34147532 myosin, light chain 10, regulatory [Homo sapiens]          37   0.023
gi|61969666 arginine-fifty homeobox [Homo sapiens]                     37   0.023
gi|29789008 Huntingtin interacting protein C isoform 2 [Homo sap...    37   0.023
gi|72534686 Huntingtin interacting protein C isoform 1 [Homo sap...    37   0.023
gi|24497440 interleukin 12 receptor, beta 1 isoform 2 precursor ...    37   0.030
gi|94680985 cyclin J-like [Homo sapiens]                               37   0.030
gi|40807368 potassium channel regulator isoform 2 [Homo sapiens]       36   0.050
gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens]     36   0.066
gi|28558977 mediator complex subunit 26 [Homo sapiens]                 36   0.066
gi|51243063 MAD2L1 binding protein isoform 1 [Homo sapiens]            35   0.15 
gi|58294160 breast carcinoma amplified sequence 4 isoform a [Hom...    34   0.19 
gi|42718017 retinoblastoma binding protein 8 isoform b [Homo sap...    34   0.25 
gi|42718015 retinoblastoma binding protein 8 isoform a [Homo sap...    34   0.25 

>gi|154146187 TFIIS central domain-containing protein 1 [Homo
           sapiens]
          Length = 381

 Score =  778 bits (2008), Expect = 0.0
 Identities = 381/381 (100%), Positives = 381/381 (100%)

Query: 1   MISAHRKLCLPGSSNSPASAFRVAGTTAVKMSDKNQIAARASLIEQLMSKRNFEDLGNHL 60
           MISAHRKLCLPGSSNSPASAFRVAGTTAVKMSDKNQIAARASLIEQLMSKRNFEDLGNHL
Sbjct: 1   MISAHRKLCLPGSSNSPASAFRVAGTTAVKMSDKNQIAARASLIEQLMSKRNFEDLGNHL 60

Query: 61  TELETIYVTKEHLQETDVVRAVYRVLKNCPSVALKKKAKCLLSKWKAVYKQTHSKARNSP 120
           TELETIYVTKEHLQETDVVRAVYRVLKNCPSVALKKKAKCLLSKWKAVYKQTHSKARNSP
Sbjct: 61  TELETIYVTKEHLQETDVVRAVYRVLKNCPSVALKKKAKCLLSKWKAVYKQTHSKARNSP 120

Query: 121 KLFPVRGNKEENSGPSHDPSQNETLGICSSNSLSSQDVAKLSEMIVPENRAIQLKPKEEH 180
           KLFPVRGNKEENSGPSHDPSQNETLGICSSNSLSSQDVAKLSEMIVPENRAIQLKPKEEH
Sbjct: 121 KLFPVRGNKEENSGPSHDPSQNETLGICSSNSLSSQDVAKLSEMIVPENRAIQLKPKEEH 180

Query: 181 FGDGDPESTGKRSSELLDPTTPMRTKCIELLYAALTSSSTDQPKADLWQNFAREIEEHVF 240
           FGDGDPESTGKRSSELLDPTTPMRTKCIELLYAALTSSSTDQPKADLWQNFAREIEEHVF
Sbjct: 181 FGDGDPESTGKRSSELLDPTTPMRTKCIELLYAALTSSSTDQPKADLWQNFAREIEEHVF 240

Query: 241 TLYSKNIKKYKTCIRSKVANLKNPRNSHLQQNLLSGTTSPREFAEMTVMEMANKELKQLR 300
           TLYSKNIKKYKTCIRSKVANLKNPRNSHLQQNLLSGTTSPREFAEMTVMEMANKELKQLR
Sbjct: 241 TLYSKNIKKYKTCIRSKVANLKNPRNSHLQQNLLSGTTSPREFAEMTVMEMANKELKQLR 300

Query: 301 ASYTESCIQEHYLPQVIDGTQTNKIKCRRCEKYNCKVTVIDRGTLFLPSWVRNSNPDEQM 360
           ASYTESCIQEHYLPQVIDGTQTNKIKCRRCEKYNCKVTVIDRGTLFLPSWVRNSNPDEQM
Sbjct: 301 ASYTESCIQEHYLPQVIDGTQTNKIKCRRCEKYNCKVTVIDRGTLFLPSWVRNSNPDEQM 360

Query: 361 MTYVICNECGEQWYHSKWVCW 381
           MTYVICNECGEQWYHSKWVCW
Sbjct: 361 MTYVICNECGEQWYHSKWVCW 381


>gi|41350335 transcription elongation factor A (SII), 3 [Homo
           sapiens]
          Length = 348

 Score =  137 bits (344), Expect = 2e-32
 Identities = 106/361 (29%), Positives = 171/361 (47%), Gaps = 34/361 (9%)

Query: 31  MSDKNQIAARASLIEQLMSKRNFEDLGNHLTELETIYVTKEHLQETDVVRAVYRVLKNCP 90
           M  + ++   A  +E++++++N E   + L +L +  ++ + LQ T +  AV  V K+C 
Sbjct: 1   MGQEEELLRIAKKLEKMVARKNTEGALDLLKKLHSCQMSIQLLQTTRIGVAVNGVRKHCS 60

Query: 91  SVALKKKAKCLLSKWKAVYK----------QTHSKARNSPKLFPVRGNKEENSGPSHDPS 140
              +   AK L+  WK +            +   KA+   K       K E +G S  P 
Sbjct: 61  DKEVVSLAKVLIKNWKRLLDSPGPPKGEKGEEREKAKKKEKGLECSDWKPE-AGLS-PPR 118

Query: 141 QNETLGICSSNSLSSQDVAKLSEMIVPENRAIQLKPKEEHFGDGDPES----TGKRSSEL 196
           +         +S+ S+  A  S       R+   K K E      P S    T   S  L
Sbjct: 119 KKREDPKTRRDSVDSKSSASSSPKRPSVERSNSSKSKAE--SPKTPSSPLTPTFASSMCL 176

Query: 197 LDPT----TPMRTKCIELLYAALTSSSTDQPKADLWQNFAREIEEHVFTLYSKNIKKYKT 252
           L P       +R KC+E+L AAL +    +         A EIE+H++        KY+ 
Sbjct: 177 LAPCYLTGDSVRDKCVEMLSAALKADDDYKDYGVNCDKMASEIEDHIYQELKSTDMKYRN 236

Query: 253 CIRSKVANLKNPRNSHLQQNLLSGTTSPREFAEMTVMEMANKELKQLRASYTESCIQEHY 312
            +RS+++NLK+PRN  L++N+LSG  S    A+MT  EMA+ EL++LR + T+  I+EH 
Sbjct: 237 RVRSRISNLKDPRNPGLRRNVLSGAISAGLIAKMTAEEMASDELRELRNAMTQEAIREHQ 296

Query: 313 LPQVIDGTQTNKIKCRRCEKYNCKVTVIDRGTLFLPSWVRNSNPDEQMMTYVICNECGEQ 372
           + +   GT T+  +C +C+K NC             + V+  + DE M T+V+CNECG +
Sbjct: 297 MAKT-GGTTTDLFQCSKCKKKNCTY-----------NQVQTRSADEPMTTFVLCNECGNR 344

Query: 373 W 373
           W
Sbjct: 345 W 345


>gi|4507385 transcription elongation factor A protein 2 isoform a
           [Homo sapiens]
          Length = 299

 Score =  132 bits (332), Expect = 5e-31
 Identities = 97/348 (27%), Positives = 159/348 (45%), Gaps = 58/348 (16%)

Query: 31  MSDKNQIAARASLIEQLMSKRNFEDLGNHLTELETIYVTKEHLQETDVVRAVYRVLKNCP 90
           M  + +IA  A  ++++++K++ E   + L EL+ + +T   LQ T V  +V  + K   
Sbjct: 2   MGKEEEIARIARRLDKMVTKKSAEGAMDLLRELKAMPITLHLLQSTRVGMSVNALRKQSS 61

Query: 91  SVALKKKAKCLLSKWKAVYKQTHSKARNSPKLFPVRGNKEENSGPSHDPSQNETLGICSS 150
              +   AK L+  WK +   + +KAR   +  P+  +  + S  + DPS+         
Sbjct: 62  DEEVIALAKSLIKSWKKLLDASDAKARERGRGMPLPTSSRDAS-EAPDPSRKR------- 113

Query: 151 NSLSSQDVAKLSEMIVPENRAIQLKPKEEHFGDGDPESTGKRSSELLDPTTPM-----RT 205
                           PE       P+   F                 P  P+     R 
Sbjct: 114 ----------------PELPRAPSTPRITTF-----------------PPVPVTCDAVRN 140

Query: 206 KCIELLYAALTSSSTDQPKADLWQNFAREIEEHVFTLYSKNIKKYKTCIRSKVANLKNPR 265
           KC E+L AAL +           +  + +IEE +F        KYK  +RS+++NLK+ +
Sbjct: 141 KCREMLTAALQTDHDHVAIGADCERLSAQIEECIFRDVGNTDMKYKNRVRSRISNLKDAK 200

Query: 266 NSHLQQNLLSGTTSPREFAEMTVMEMANKELKQLRASYTESCIQEHYLPQVIDGTQTNKI 325
           N  L++N+L G  +P++ A MT  EMA+ ELK++R + T+  I+EH + +   GTQT+  
Sbjct: 201 NPDLRRNVLCGAITPQQIAVMTSEEMASDELKEIRKAMTKEAIREHQMART-GGTQTDLF 259

Query: 326 KCRRCEKYNCKVTVIDRGTLFLPSWVRNSNPDEQMMTYVICNECGEQW 373
            C +C K NC  T            V+  + DE M T+V+CNECG +W
Sbjct: 260 TCGKCRKKNCTYT-----------QVQTRSSDEPMTTFVVCNECGNRW 296


>gi|5803191 transcription elongation factor A 1 isoform 1 [Homo
           sapiens]
          Length = 301

 Score =  128 bits (322), Expect = 7e-30
 Identities = 95/343 (27%), Positives = 160/343 (46%), Gaps = 49/343 (14%)

Query: 34  KNQIAARASLIEQLMSKRNFEDLGNHLTELETIYVTKEHLQETDVVRAVYRVLKNCPSVA 93
           ++++   A  +++++ K+N     + L EL+ I +T E LQ T +  +V  + K      
Sbjct: 2   EDEVVRFAKKMDKMVQKKNAAGALDLLKELKNIPMTLELLQSTRIGMSVNAIRKQSTDEE 61

Query: 94  LKKKAKCLLSKWKAVYKQTHSKARNSPKLFPVRGNKEENSGPSHDPSQNETL---GICSS 150
           +   AK L+  WK +                         GPS +   +E      I S 
Sbjct: 62  VTSLAKSLIKSWKKLL-----------------------DGPSTEKDLDEKKKEPAITSQ 98

Query: 151 NSLSSQDVAKLSEMIVPENRAIQLKPKEEHFGDGDPESTGKRSSELLDPTTPMRTKCIEL 210
           NS  +++ +  S  +   NR  +   ++ +       S+  R+    D    +R KC E+
Sbjct: 99  NSPEAREESTSSGNV--SNRKDETNARDTYV------SSFPRAPSTSDS---VRLKCREM 147

Query: 211 LYAALTSSSTDQPKADLWQNFAREIEEHVFTLYSKNIKKYKTCIRSKVANLKNPRNSHLQ 270
           L AAL +           +    +IEE ++        KYK  +RS+++NLK+ +N +L+
Sbjct: 148 LAAALRTGDDYIAIGADEEELGSQIEEAIYQEIRNTDMKYKNRVRSRISNLKDAKNPNLR 207

Query: 271 QNLLSGTTSPREFAEMTVMEMANKELKQLRASYTESCIQEHYLPQVIDGTQTNKIKCRRC 330
           +N+L G   P  FA MT  EMA+ ELK++R + T+  I+EH + +   GTQT+   C +C
Sbjct: 208 KNVLCGNIPPDLFARMTAEEMASDELKEMRKNLTKEAIREHQMAKT-GGTQTDLFTCGKC 266

Query: 331 EKYNCKVTVIDRGTLFLPSWVRNSNPDEQMMTYVICNECGEQW 373
           +K NC  T            V+  + DE M T+V+CNECG +W
Sbjct: 267 KKKNCTYT-----------QVQTRSADEPMTTFVVCNECGNRW 298


>gi|239749424 PREDICTED: hypothetical protein XP_002347041 [Homo
           sapiens]
          Length = 287

 Score =  125 bits (313), Expect = 8e-29
 Identities = 94/330 (28%), Positives = 152/330 (46%), Gaps = 49/330 (14%)

Query: 47  LMSKRNFEDLGNHLTELETIYVTKEHLQETDVVRAVYRVLKNCPSVALKKKAKCLLSKWK 106
           ++ K+N     + L EL+ I +T E LQ T +  +V  + K      +   AK L+  WK
Sbjct: 1   MVQKKNAAGALDLLKELKNIPMTLELLQSTRIGMSVNAIRKQSTDEEVTSLAKSLIKSWK 60

Query: 107 AVYKQTHSKARNSPKLFPVRGNKEENSGPSHDPSQNETL---GICSSNSLSSQDVAKLSE 163
            +                         GPS +   +E      I S NS  +++ +  S 
Sbjct: 61  KLL-----------------------DGPSTEKDLDEKKKEPAITSQNSPEAREESTSSG 97

Query: 164 MIVPENRAIQLKPKEEHFGDGDPESTGKRSSELLDPTTPMRTKCIELLYAALTSSSTDQP 223
            +   NR  +   ++ +       S+  R+    D    +R KC E+L AAL +      
Sbjct: 98  NV--SNRKDETNARDTYV------SSFPRAPSTSDS---VRLKCREMLAAALRTGDDYIA 146

Query: 224 KADLWQNFAREIEEHVFTLYSKNIKKYKTCIRSKVANLKNPRNSHLQQNLLSGTTSPREF 283
                +    +IEE ++        KYK  +RS+++NLK+ +N +L++N+L G   P  F
Sbjct: 147 IGADEEELGSQIEEAIYQEIRNTDMKYKNRVRSRISNLKDAKNPNLRKNVLCGNIPPDLF 206

Query: 284 AEMTVMEMANKELKQLRASYTESCIQEHYLPQVIDGTQTNKIKCRRCEKYNCKVTVIDRG 343
           A MT  EMA+ ELK++R + T+  I+EH + +   GTQT+   C +C+K NC  T     
Sbjct: 207 ARMTAEEMASDELKEMRKNLTKEAIREHQMAKT-GGTQTDLFTCGKCKKKNCTYT----- 260

Query: 344 TLFLPSWVRNSNPDEQMMTYVICNECGEQW 373
                  V+  + DE M T+V+CNECG +W
Sbjct: 261 ------QVQTRSADEPMTTFVVCNECGNRW 284


>gi|38505156 transcription elongation factor A protein 2 isoform b
           [Homo sapiens]
          Length = 272

 Score =  122 bits (307), Expect = 4e-28
 Identities = 91/319 (28%), Positives = 142/319 (44%), Gaps = 58/319 (18%)

Query: 60  LTELETIYVTKEHLQETDVVRAVYRVLKNCPSVALKKKAKCLLSKWKAVYKQTHSKARNS 119
           L EL+ + +T   LQ T V  +V  + K      +   AK L+  WK +   + +KAR  
Sbjct: 4   LRELKAMPITLHLLQSTRVGMSVNALRKQSSDEEVIALAKSLIKSWKKLLDASDAKARER 63

Query: 120 PKLFPVRGNKEENSGPSHDPSQNETLGICSSNSLSSQDVAKLSEMIVPENRAIQLKPKEE 179
            +  P+  +  + S  + DPS+                         PE       P+  
Sbjct: 64  GRGMPLPTSSRDAS-EAPDPSRKR-----------------------PELPRAPSTPRIT 99

Query: 180 HFGDGDPESTGKRSSELLDPTTPM-----RTKCIELLYAALTSSSTDQPKADLWQNFARE 234
            F                 P  P+     R KC E+L AAL +           +  + +
Sbjct: 100 TF-----------------PPVPVTCDAVRNKCREMLTAALQTDHDHVAIGADCERLSAQ 142

Query: 235 IEEHVFTLYSKNIKKYKTCIRSKVANLKNPRNSHLQQNLLSGTTSPREFAEMTVMEMANK 294
           IEE +F        KYK  +RS+++NLK+ +N  L++N+L G  +P++ A MT  EMA+ 
Sbjct: 143 IEECIFRDVGNTDMKYKNRVRSRISNLKDAKNPDLRRNVLCGAITPQQIAVMTSEEMASD 202

Query: 295 ELKQLRASYTESCIQEHYLPQVIDGTQTNKIKCRRCEKYNCKVTVIDRGTLFLPSWVRNS 354
           ELK++R + T+  I+EH + +   GTQT+   C +C K NC  T            V+  
Sbjct: 203 ELKEIRKAMTKEAIREHQMART-GGTQTDLFTCGKCRKKNCTYT-----------QVQTR 250

Query: 355 NPDEQMMTYVICNECGEQW 373
           + DE M T+V+CNECG +W
Sbjct: 251 SSDEPMTTFVVCNECGNRW 269


>gi|45439355 transcription elongation factor A 1 isoform 2 [Homo
           sapiens]
          Length = 280

 Score =  117 bits (292), Expect = 2e-26
 Identities = 87/296 (29%), Positives = 141/296 (47%), Gaps = 27/296 (9%)

Query: 82  VYRVLKNCPSVALKKKAKCLLS-KWKAVYKQTHSKARNSPKLFPVRGNKEENSGPSHDPS 140
           V R  K    +  KK A   +     A+ KQ+  +   S     ++  K+   GPS +  
Sbjct: 5   VVRFAKKMDKMVQKKNASTRIGMSVNAIRKQSTDEEVTSLAKSLIKSWKKLLDGPSTEKD 64

Query: 141 QNETL---GICSSNSLSSQDVAKLSEMIVPENRAIQLKPKEEHFGDGDPESTGKRSSELL 197
            +E      I S NS  +++ +  S  +   NR  +   ++ +       S+  R+    
Sbjct: 65  LDEKKKEPAITSQNSPEAREESTSSGNV--SNRKDETNARDTYV------SSFPRAPSTS 116

Query: 198 DPTTPMRTKCIELLYAALTSSSTDQPKADLWQNFAREIEEHVFTLYSKNIKKYKTCIRSK 257
           D    +R KC E+L AAL +           +    +IEE ++        KYK  +RS+
Sbjct: 117 DS---VRLKCREMLAAALRTGDDYIAIGADEEELGSQIEEAIYQEIRNTDMKYKNRVRSR 173

Query: 258 VANLKNPRNSHLQQNLLSGTTSPREFAEMTVMEMANKELKQLRASYTESCIQEHYLPQVI 317
           ++NLK+ +N +L++N+L G   P  FA MT  EMA+ ELK++R + T+  I+EH + +  
Sbjct: 174 ISNLKDAKNPNLRKNVLCGNIPPDLFARMTAEEMASDELKEMRKNLTKEAIREHQMAKT- 232

Query: 318 DGTQTNKIKCRRCEKYNCKVTVIDRGTLFLPSWVRNSNPDEQMMTYVICNECGEQW 373
            GTQT+   C +C+K NC  T            V+  + DE M T+V+CNECG +W
Sbjct: 233 GGTQTDLFTCGKCKKKNCTYT-----------QVQTRSADEPMTTFVVCNECGNRW 277


>gi|7662018 PHD finger protein 3 [Homo sapiens]
          Length = 2039

 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 30/92 (32%), Positives = 49/92 (53%), Gaps = 1/92 (1%)

Query: 209  ELLYAALTSSSTDQPKADLWQNFAREIEEHVFTLYSKNIKKYKTCIRSKVANLKNPRNSH 268
            ++L   LT S+   P+       A +IE+ +F+ +     KYK   RS + NLK+P+N+ 
Sbjct: 937  DILMKRLTDSNLKVPEEKA-AKVATKIEKELFSFFRDTDAKYKNKYRSLMFNLKDPKNNI 995

Query: 269  LQQNLLSGTTSPREFAEMTVMEMANKELKQLR 300
            L + +L G  +P     M+  E+A+KEL   R
Sbjct: 996  LFKKVLKGEVTPDHLIRMSPEELASKELAAWR 1027


>gi|47271475 SPOC domain containing 1 [Homo sapiens]
          Length = 1216

 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 26/92 (28%), Positives = 46/92 (50%)

Query: 209 ELLYAALTSSSTDQPKADLWQNFAREIEEHVFTLYSKNIKKYKTCIRSKVANLKNPRNSH 268
           E+L+  L          ++ +  A  IE  ++ L      +YKT  RS + NL++PRN  
Sbjct: 618 EVLWTRLRELPDPVLSEEVVEGIAAGIEAALWDLTQGTNGRYKTKYRSLLFNLRDPRNLD 677

Query: 269 LQQNLLSGTTSPREFAEMTVMEMANKELKQLR 300
           L   ++ G  +P +   M+ M++A +EL + R
Sbjct: 678 LFLKVVHGDVTPYDLVRMSSMQLAPQELARWR 709


>gi|28372523 intraflagellar transport protein IFT20 [Homo sapiens]
          Length = 148

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 22/40 (55%), Positives = 27/40 (67%)

Query: 2   ISAHRKLCLPGSSNSPASAFRVAGTTAVKMSDKNQIAARA 41
           ISAH KLCL  SS+SP S  RV GTT  + S+  QI ++A
Sbjct: 85  ISAHCKLCLSDSSDSPTSPSRVGGTTGHRCSELAQIYSKA 124


>gi|219881538 hypothetical protein LOC199870 isoform 2 [Homo
          sapiens]
          Length = 312

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 20/29 (68%), Positives = 23/29 (79%)

Query: 2  ISAHRKLCLPGSSNSPASAFRVAGTTAVK 30
          ISAH  L LPGSS+SPAS+ RVAG T +K
Sbjct: 56 ISAHCNLHLPGSSDSPASSSRVAGITGIK 84


>gi|219881536 hypothetical protein LOC199870 isoform 1 [Homo
          sapiens]
          Length = 341

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 20/29 (68%), Positives = 23/29 (79%)

Query: 2  ISAHRKLCLPGSSNSPASAFRVAGTTAVK 30
          ISAH  L LPGSS+SPAS+ RVAG T +K
Sbjct: 56 ISAHCNLHLPGSSDSPASSSRVAGITGIK 84


>gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]
          Length = 2240

 Score = 39.7 bits (91), Expect = 0.005
 Identities = 30/115 (26%), Positives = 48/115 (41%), Gaps = 4/115 (3%)

Query: 186 PESTGKRSSELLDPTTPMRTKCIELLYAALTSSSTDQPKADLWQN----FAREIEEHVFT 241
           P   G  S+    P + +R      L   L     D     + +N     A  IE+ +F 
Sbjct: 653 PGRLGAMSAAPSQPNSQIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFN 712

Query: 242 LYSKNIKKYKTCIRSKVANLKNPRNSHLQQNLLSGTTSPREFAEMTVMEMANKEL 296
           L+     +YK+  RS + NLK+P+N  L   +L    S  +   +   E+ +KEL
Sbjct: 713 LFQVTDNRYKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKEL 767


>gi|71044477 death inducer-obliterator 1 isoform b [Homo sapiens]
          Length = 1189

 Score = 39.7 bits (91), Expect = 0.005
 Identities = 30/115 (26%), Positives = 48/115 (41%), Gaps = 4/115 (3%)

Query: 186 PESTGKRSSELLDPTTPMRTKCIELLYAALTSSSTDQPKADLWQN----FAREIEEHVFT 241
           P   G  S+    P + +R      L   L     D     + +N     A  IE+ +F 
Sbjct: 653 PGRLGAMSAAPSQPNSQIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFN 712

Query: 242 LYSKNIKKYKTCIRSKVANLKNPRNSHLQQNLLSGTTSPREFAEMTVMEMANKEL 296
           L+     +YK+  RS + NLK+P+N  L   +L    S  +   +   E+ +KEL
Sbjct: 713 LFQVTDNRYKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKEL 767


>gi|6005810 mitogen-activated protein kinase kinase kinase kinase 1
           isoform 2 [Homo sapiens]
          Length = 833

 Score = 39.7 bits (91), Expect = 0.005
 Identities = 20/28 (71%), Positives = 21/28 (75%)

Query: 2   ISAHRKLCLPGSSNSPASAFRVAGTTAV 29
           IS H  L LPGSSNSPASA RVAG T +
Sbjct: 806 ISPHCNLLLPGSSNSPASASRVAGITGL 833


>gi|58533176 zinc finger, matrin type 1 isoform 1 [Homo sapiens]
          Length = 638

 Score = 38.9 bits (89), Expect = 0.008
 Identities = 19/26 (73%), Positives = 22/26 (84%)

Query: 2  ISAHRKLCLPGSSNSPASAFRVAGTT 27
          ISAH  L LPGSS+SPASA ++AGTT
Sbjct: 15 ISAHCSLHLPGSSDSPASASQIAGTT 40


>gi|148839316 NIMA-related kinase 4 [Homo sapiens]
          Length = 841

 Score = 38.1 bits (87), Expect = 0.013
 Identities = 22/45 (48%), Positives = 28/45 (62%)

Query: 2   ISAHRKLCLPGSSNSPASAFRVAGTTAVKMSDKNQIAARASLIEQ 46
           I AH  L L GSS+SPASA RVAG T V    ++Q+A    + +Q
Sbjct: 470 ILAHSNLRLLGSSDSPASASRVAGITGVCHHAQDQVAGECIIEKQ 514


>gi|34147532 myosin, light chain 10, regulatory [Homo sapiens]
          Length = 226

 Score = 37.4 bits (85), Expect = 0.023
 Identities = 30/74 (40%), Positives = 37/74 (50%), Gaps = 16/74 (21%)

Query: 1   MISAHRKLCLPGSSNSPASAFRVAGTTAVKMSDKNQIAARASLIEQLMSKRNFEDLGNHL 60
           MISAH  LCL GSSNSPASA     + A  + D+N    R   I++       EDL +  
Sbjct: 70  MISAHCNLCLTGSSNSPASA-----SQAFTIMDQN----RDGFIDK-------EDLRDTF 113

Query: 61  TELETIYVTKEHLQ 74
             L  I V  E L+
Sbjct: 114 AALGRINVKNEELE 127


>gi|61969666 arginine-fifty homeobox [Homo sapiens]
          Length = 315

 Score = 37.4 bits (85), Expect = 0.023
 Identities = 22/57 (38%), Positives = 33/57 (57%), Gaps = 3/57 (5%)

Query: 2   ISAHRKLCLPGSSNSPASAFRVAGTTAVKMSDKNQIA---ARASLIEQLMSKRNFED 55
           +SA+  L LPGS++ P SA RVA TTA++   K + +    +   +E L S+  F D
Sbjct: 48  VSAYCSLNLPGSTDPPTSASRVAATTAIRRRHKERTSFTHQQYEELEALFSQTMFPD 104


>gi|29789008 Huntingtin interacting protein C isoform 2 [Homo
           sapiens]
          Length = 858

 Score = 37.4 bits (85), Expect = 0.023
 Identities = 61/265 (23%), Positives = 99/265 (37%), Gaps = 38/265 (14%)

Query: 90  PSVALKKKAKCLLSK--WKAVYKQTHSKARNSPKLFPVRGNKEENSGPSHDPSQNETLGI 147
           PSV LK KA+ LLS+  WK  YK    K        P   N +        P   + L +
Sbjct: 117 PSV-LKSKAELLLSQCPWKE-YKSDTGK--------PYYYNNQSKESRWTRPKDLDDLEV 166

Query: 148 CSSNSLSSQDVAKLSEMIVPENRAIQLKPKEEHFGDG-------DPESTGKRSSELLDPT 200
                 + +   +L + + P+    Q  P     G         +PE  G    ++L+ T
Sbjct: 167 LVKQEAAGKQQQQLPQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEPGGSEDCDVLEAT 226

Query: 201 TPMRTKCIELLYAALTSSSTDQPKADLWQNFAREIEEHVFTLYSKNIKKYKTCIRSKVAN 260
            P+    ++ L    +SS   QP+ +  ++   + E     L   N +K K   +  + +
Sbjct: 227 QPLEQGFLQQLEEGPSSSGQHQPQQEEEES---KPEPERSGLSWSNREKAKQAFKELLRD 283

Query: 261 LKNPRNSHLQQNLLSGTTSPREF-------------AEMTVMEMANKELKQLRASYTESC 307
              P N+  +Q +    T PR               A     E   KE  +LRA   +  
Sbjct: 284 KAVPSNASWEQAMKMVVTDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQT 343

Query: 308 IQEHYLPQVIDGTQTNKIKCRRCEK 332
           +Q H+L Q      T+  + RR E+
Sbjct: 344 LQ-HFLEQ--HERMTSTTRYRRAEQ 365


>gi|72534686 Huntingtin interacting protein C isoform 1 [Homo
           sapiens]
          Length = 871

 Score = 37.4 bits (85), Expect = 0.023
 Identities = 61/265 (23%), Positives = 99/265 (37%), Gaps = 38/265 (14%)

Query: 90  PSVALKKKAKCLLSK--WKAVYKQTHSKARNSPKLFPVRGNKEENSGPSHDPSQNETLGI 147
           PSV LK KA+ LLS+  WK  YK    K        P   N +        P   + L +
Sbjct: 123 PSV-LKSKAELLLSQCPWKE-YKSDTGK--------PYYYNNQSKESRWTRPKDLDDLEV 172

Query: 148 CSSNSLSSQDVAKLSEMIVPENRAIQLKPKEEHFGDG-------DPESTGKRSSELLDPT 200
                 + +   +L + + P+    Q  P     G         +PE  G    ++L+ T
Sbjct: 173 LVKQEAAGKQQQQLPQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEPGGSEDCDVLEAT 232

Query: 201 TPMRTKCIELLYAALTSSSTDQPKADLWQNFAREIEEHVFTLYSKNIKKYKTCIRSKVAN 260
            P+    ++ L    +SS   QP+ +  ++   + E     L   N +K K   +  + +
Sbjct: 233 QPLEQGFLQQLEEGPSSSGQHQPQQEEEES---KPEPERSGLSWSNREKAKQAFKELLRD 289

Query: 261 LKNPRNSHLQQNLLSGTTSPREF-------------AEMTVMEMANKELKQLRASYTESC 307
              P N+  +Q +    T PR               A     E   KE  +LRA   +  
Sbjct: 290 KAVPSNASWEQAMKMVVTDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQT 349

Query: 308 IQEHYLPQVIDGTQTNKIKCRRCEK 332
           +Q H+L Q      T+  + RR E+
Sbjct: 350 LQ-HFLEQ--HERMTSTTRYRRAEQ 371


>gi|24497440 interleukin 12 receptor, beta 1 isoform 2 precursor
           [Homo sapiens]
          Length = 381

 Score = 37.0 bits (84), Expect = 0.030
 Identities = 19/29 (65%), Positives = 21/29 (72%)

Query: 1   MISAHRKLCLPGSSNSPASAFRVAGTTAV 29
           MISAH  L LP S +SPASA RVAG T +
Sbjct: 343 MISAHCNLRLPDSRDSPASASRVAGITGI 371


>gi|94680985 cyclin J-like [Homo sapiens]
          Length = 435

 Score = 37.0 bits (84), Expect = 0.030
 Identities = 40/123 (32%), Positives = 56/123 (45%), Gaps = 23/123 (18%)

Query: 1   MISAHRKLCLPGSSNSPASA-------FRVAGTTAVKMSDKNQIAARASLIE--QLMSKR 51
           MISAH  L LPGSSNSPASA        +VA TT  K  D+     +   I   +++S +
Sbjct: 108 MISAHCNLHLPGSSNSPASAPHPPPTPPQVAETTG-KFEDREDHVPKLEQINSTRILSSQ 166

Query: 52  NF-----EDLGNHLTELETI-----YVTKEHLQETDVVRAVYRVLKNC---PSVALKKKA 98
           NF     E L   L  LE         T  H  +  ++ +V +   +C   P+   +K  
Sbjct: 167 NFTLTKKELLSTELLLLEAFSWNLCLPTPAHFLDYYLLASVSQKDHHCHTWPTTCPRKTK 226

Query: 99  KCL 101
           +CL
Sbjct: 227 ECL 229


>gi|40807368 potassium channel regulator isoform 2 [Homo sapiens]
          Length = 229

 Score = 36.2 bits (82), Expect = 0.050
 Identities = 19/29 (65%), Positives = 22/29 (75%)

Query: 1   MISAHRKLCLPGSSNSPASAFRVAGTTAV 29
           +ISAH  L L GSS+SPASA RVAG T +
Sbjct: 199 VISAHHNLRLWGSSDSPASASRVAGITGM 227


>gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens]
          Length = 475

 Score = 35.8 bits (81), Expect = 0.066
 Identities = 18/29 (62%), Positives = 21/29 (72%)

Query: 1   MISAHRKLCLPGSSNSPASAFRVAGTTAV 29
           MI AH  L LPGS +SPASA + AGTT +
Sbjct: 437 MILAHCNLRLPGSRDSPASASQAAGTTGM 465


>gi|28558977 mediator complex subunit 26 [Homo sapiens]
          Length = 600

 Score = 35.8 bits (81), Expect = 0.066
 Identities = 20/63 (31%), Positives = 33/63 (52%)

Query: 51  RNFEDLGNHLTELETIYVTKEHLQETDVVRAVYRVLKNCPSVALKKKAKCLLSKWKAVYK 110
           RN   +   ++ LE   +TKE L+ET + + +  V K   +  L K+AK LL  W+ + +
Sbjct: 26  RNMVAVLEVISSLEKYPITKEALEETRLGKLINDVRKKTKNEELAKRAKKLLRSWQKLIE 85

Query: 111 QTH 113
             H
Sbjct: 86  PAH 88


>gi|51243063 MAD2L1 binding protein isoform 1 [Homo sapiens]
          Length = 306

 Score = 34.7 bits (78), Expect = 0.15
 Identities = 23/56 (41%), Positives = 31/56 (55%), Gaps = 1/56 (1%)

Query: 1  MISAHRKLCLPGSSNSPASAFRVAGTTAVKMSDKNQIAARASLIEQLMSKRNFEDL 56
          M SAH    LPGS +SPASA +VA    ++  +K++    AS IE L +    E L
Sbjct: 21 MTSAHHNFRLPGSRDSPASASQVAEIIDLEWYEKSE-ETHASQIELLETSSTQEPL 75


>gi|58294160 breast carcinoma amplified sequence 4 isoform a [Homo
           sapiens]
          Length = 211

 Score = 34.3 bits (77), Expect = 0.19
 Identities = 19/38 (50%), Positives = 23/38 (60%)

Query: 2   ISAHRKLCLPGSSNSPASAFRVAGTTAVKMSDKNQIAA 39
           I A   L LPGSS+SPASA +VAG T V  +    + A
Sbjct: 170 IPARCNLRLPGSSDSPASASQVAGITEVTCTGARDVRA 207


>gi|42718017 retinoblastoma binding protein 8 isoform b [Homo
           sapiens]
          Length = 867

 Score = 33.9 bits (76), Expect = 0.25
 Identities = 61/296 (20%), Positives = 116/296 (39%), Gaps = 27/296 (9%)

Query: 43  LIEQLMSKRN-FEDLGNHLTELETIYVTKEHLQETDVVRAVYRVLKNCPSVALKKKAKCL 101
           LI +LM++RN  ++    L+E     +  +   +   +     V+ + P  A        
Sbjct: 116 LITELMNERNTLQEENKKLSEQLQQKIENDQQHQAAELECEEDVIPDSPITAFSFSGVNR 175

Query: 102 LSKWKAVY----KQTHSKARNSPKLFPVRGNKEENSGPSHDPSQNETLGICSSNSLSSQD 157
           L + +  +    +QTH+K  +S     +R   + ++ P H+P++NE L +  +   S   
Sbjct: 176 LRRKENPHVRYIEQTHTKLEHSVCANEMRKVSKSSTHPQHNPNENEIL-VADTYDQSQSP 234

Query: 158 VAKL--SEMIVPENRAIQLKP-KEEHFGDGDPESTGKRSSELLDPTTPMRTKCIELLYAA 214
           +AK   +    P+  +  L     E  G G  E      SE   P +P+  +    LY  
Sbjct: 235 MAKAHGTSSYTPDKSSFNLATVVAETLGLGVQE-----ESETQGPMSPLGDE----LYHC 285

Query: 215 LTSSSTDQPKADLWQNFAREIEEHVFTLYSKNIKKYKTCIRSKVANLKNPRNSHLQQN-- 272
           L  +   QP  +  +N    +     T  +   ++  T + S V    +   S L  N  
Sbjct: 286 LEGNHKKQPFEESTRNTEDSLRFSDSTSKTPPQEELPTRVSSPVFGATSSIKSGLDLNTS 345

Query: 273 LLSGTTSPREFAEMTVMEMAN---KELKQLRASYTESCIQEHYLPQVIDGTQTNKI 325
           L      P +   +  +  +N     L++ R+   +S +  H+      G++ NKI
Sbjct: 346 LSPSLLQPGKKKHLKTLPFSNTCISRLEKTRSKSEDSALFTHHSL----GSEVNKI 397


>gi|42718015 retinoblastoma binding protein 8 isoform a [Homo
           sapiens]
          Length = 897

 Score = 33.9 bits (76), Expect = 0.25
 Identities = 61/296 (20%), Positives = 116/296 (39%), Gaps = 27/296 (9%)

Query: 43  LIEQLMSKRN-FEDLGNHLTELETIYVTKEHLQETDVVRAVYRVLKNCPSVALKKKAKCL 101
           LI +LM++RN  ++    L+E     +  +   +   +     V+ + P  A        
Sbjct: 116 LITELMNERNTLQEENKKLSEQLQQKIENDQQHQAAELECEEDVIPDSPITAFSFSGVNR 175

Query: 102 LSKWKAVY----KQTHSKARNSPKLFPVRGNKEENSGPSHDPSQNETLGICSSNSLSSQD 157
           L + +  +    +QTH+K  +S     +R   + ++ P H+P++NE L +  +   S   
Sbjct: 176 LRRKENPHVRYIEQTHTKLEHSVCANEMRKVSKSSTHPQHNPNENEIL-VADTYDQSQSP 234

Query: 158 VAKL--SEMIVPENRAIQLKP-KEEHFGDGDPESTGKRSSELLDPTTPMRTKCIELLYAA 214
           +AK   +    P+  +  L     E  G G  E      SE   P +P+  +    LY  
Sbjct: 235 MAKAHGTSSYTPDKSSFNLATVVAETLGLGVQE-----ESETQGPMSPLGDE----LYHC 285

Query: 215 LTSSSTDQPKADLWQNFAREIEEHVFTLYSKNIKKYKTCIRSKVANLKNPRNSHLQQN-- 272
           L  +   QP  +  +N    +     T  +   ++  T + S V    +   S L  N  
Sbjct: 286 LEGNHKKQPFEESTRNTEDSLRFSDSTSKTPPQEELPTRVSSPVFGATSSIKSGLDLNTS 345

Query: 273 LLSGTTSPREFAEMTVMEMAN---KELKQLRASYTESCIQEHYLPQVIDGTQTNKI 325
           L      P +   +  +  +N     L++ R+   +S +  H+      G++ NKI
Sbjct: 346 LSPSLLQPGKKKHLKTLPFSNTCISRLEKTRSKSEDSALFTHHSL----GSEVNKI 397


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.127    0.377 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,032,800
Number of Sequences: 37866
Number of extensions: 652757
Number of successful extensions: 2278
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 37
Number of HSP's successfully gapped in prelim test: 31
Number of HSP's that attempted gapping in prelim test: 2221
Number of HSP's gapped (non-prelim): 75
length of query: 381
length of database: 18,247,518
effective HSP length: 104
effective length of query: 277
effective length of database: 14,309,454
effective search space: 3963718758
effective search space used: 3963718758
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.