Guide to the Human Genome
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Name: NEK4 Sequence: fasta or formatted (841aa) NCBI GI: 148839316
Description:

NIMA-related kinase 4

Referenced in:

Dual-Specificity Protein Kinases

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.2         44           2
 C cysteine            1.7         14           2
 D aspartate           4.4         37           1
 E glutamate           9.2         77           3
 F phenylalanine       2.1         18           2
 G glycine             5.8         49           2
 H histidine           2.6         22           2
 I isoleucine          4.8         40           2
 K lysine              7.1         60           2
 L leucine             9.6         81           2
 M methionine          2.1         18           1
 N asparagine          3.6         30           2
 P proline             5.4         45           2
 Q glutamine           5.7         48           1
 R arginine            6.8         57           3
 S serine             10.5         88           3
 T threonine           4.2         35           2
 V valine              6.1         51           2
 W tryptophan          0.5          4           1
 Y tyrosine            2.7         23           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   NIMA-related kinase 4 
NEK1                  0.165   NIMA-related kinase 1 
NEK3                  0.141   NIMA-related kinase 3 isoform a 
NEK3                  0.141   NIMA-related kinase 3 isoform a 
NEK3                  0.140   NIMA-related kinase 3 isoform b 
NEK5                  0.139   NIMA-related kinase 5 
NEK11                 0.124   NIMA-related kinase 11 isoform 2 
NEK11                 0.124   NIMA-related kinase 11 isoform 3 
NEK11                 0.124   NIMA-related kinase 11 isoform 1 
NEK8                  0.116   NIMA-related kinase 8 
NEK9                  0.116   NIMA-related kinase 9 
NEK2                  0.102   NIMA-related kinase 2 
NEK7                  0.100   NIMA-related kinase 7 
NEK6                  0.096   NIMA-related kinase 6 isoform 1 
NEK6                  0.096   NIMA-related kinase 6 isoform 2 
STK36                 0.076   serine/threonine kinase 36 
YSK4                  0.074   Yeast Sps1/Ste20-related kinase 4 isoform 1 
YSK4                  0.074   Yeast Sps1/Ste20-related kinase 4 isoform 2 
PLK2                  0.072   polo-like kinase 2 
MINK1                 0.070   misshapen/NIK-related kinase isoform 4 
MINK1                 0.070   misshapen/NIK-related kinase isoform 2 
MINK1                 0.070   misshapen/NIK-related kinase isoform 3 
MINK1                 0.070   misshapen/NIK-related kinase isoform 1 
MAP4K4                0.069   mitogen-activated protein kinase kinase kinase kinas...
EIF2AK2               0.069   eukaryotic translation initiation factor 2-alpha ki...
EIF2AK2               0.069   eukaryotic translation initiation factor 2-alpha kina...
RPS6KA2               0.068   ribosomal protein S6 kinase, 90kDa, polypeptide 2 is...
RPS6KA2               0.068   ribosomal protein S6 kinase, 90kDa, polypeptide 2 is...
MAP4K4                0.067   mitogen-activated protein kinase kinase kinase kinas...
MAP4K4                0.067   mitogen-activated protein kinase kinase kinase kinas...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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