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Search of human proteins with 153946395
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|153946395 tenascin C precursor [Homo sapiens]
(2201 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|153946395 tenascin C precursor [Homo sapiens] 4561 0.0
gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens] 937 0.0
gi|157384973 tenascin R [Homo sapiens] 645 0.0
gi|62988324 tenascin N [Homo sapiens] 544 e-154
gi|20665034 tenascin XB isoform 2 [Homo sapiens] 521 e-147
gi|47132557 fibronectin 1 isoform 1 preproprotein [Homo sapiens] 380 e-105
gi|47132551 fibronectin 1 isoform 2 preproprotein [Homo sapiens] 379 e-104
gi|47132549 fibronectin 1 isoform 6 preproprotein [Homo sapiens] 364 e-100
gi|16933542 fibronectin 1 isoform 3 preproprotein [Homo sapiens] 360 6e-99
gi|47132555 fibronectin 1 isoform 4 preproprotein [Homo sapiens] 360 6e-99
gi|47132553 fibronectin 1 isoform 5 preproprotein [Homo sapiens] 358 2e-98
gi|14192943 multiple EGF-like-domains 10 [Homo sapiens] 237 1e-61
gi|181336739 multiple EGF-like-domains 11 [Homo sapiens] 234 5e-61
gi|170016091 odz, odd Oz/ten-m homolog 2 [Homo sapiens] 233 1e-60
gi|122937400 odz, odd Oz/ten-m homolog 3 [Homo sapiens] 233 1e-60
gi|24041035 notch 2 preproprotein [Homo sapiens] 231 5e-60
gi|21704279 jagged 2 isoform b precursor [Homo sapiens] 228 5e-59
gi|4557679 jagged 1 precursor [Homo sapiens] 226 2e-58
gi|169790825 odz, odd Oz/ten-m homolog 4 [Homo sapiens] 223 2e-57
gi|148833508 notch1 preproprotein [Homo sapiens] 221 6e-57
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 219 3e-56
gi|21704277 jagged 2 isoform a precursor [Homo sapiens] 218 5e-56
gi|122937343 platelet endothelial aggregation receptor 1 [Homo s... 216 2e-55
gi|134244285 Notch homolog 3 [Homo sapiens] 213 2e-54
gi|122937283 6720455I24Rik homolog [Homo sapiens] 213 2e-54
gi|110347400 odz, odd Oz/ten-m homolog 1 isoform 3 [Homo sapiens] 209 3e-53
gi|253970446 odz, odd Oz/ten-m homolog 1 isoform 2 [Homo sapiens] 209 3e-53
gi|253970444 odz, odd Oz/ten-m homolog 1 isoform 1 [Homo sapiens] 209 3e-53
gi|93141049 collagen, type XII, alpha 1 short isoform precursor ... 202 2e-51
gi|93141047 collagen, type XII, alpha 1 long isoform precursor [... 202 2e-51
>gi|153946395 tenascin C precursor [Homo sapiens]
Length = 2201
Score = 4561 bits (11831), Expect = 0.0
Identities = 2201/2201 (100%), Positives = 2201/2201 (100%)
Query: 1 MGAMTQLLAGVFLAFLALATEGGVLKKVIRHKRQSGVNATLPEENQPVVFNHVYNIKLPV 60
MGAMTQLLAGVFLAFLALATEGGVLKKVIRHKRQSGVNATLPEENQPVVFNHVYNIKLPV
Sbjct: 1 MGAMTQLLAGVFLAFLALATEGGVLKKVIRHKRQSGVNATLPEENQPVVFNHVYNIKLPV 60
Query: 61 GSQCSVDLESASGEKDLAPPSEPSESFQEHTVDGENQIVFTHRINIPRRACGCAAAPDVK 120
GSQCSVDLESASGEKDLAPPSEPSESFQEHTVDGENQIVFTHRINIPRRACGCAAAPDVK
Sbjct: 61 GSQCSVDLESASGEKDLAPPSEPSESFQEHTVDGENQIVFTHRINIPRRACGCAAAPDVK 120
Query: 121 ELLSRLEELENLVSSLREQCTAGAGCCLQPATGRLDTRPFCSGRGNFSTEGCGCVCEPGW 180
ELLSRLEELENLVSSLREQCTAGAGCCLQPATGRLDTRPFCSGRGNFSTEGCGCVCEPGW
Sbjct: 121 ELLSRLEELENLVSSLREQCTAGAGCCLQPATGRLDTRPFCSGRGNFSTEGCGCVCEPGW 180
Query: 181 KGPNCSEPECPGNCHLRGRCIDGQCICDDGFTGEDCSQLACPSDCNDQGKCVNGVCICFE 240
KGPNCSEPECPGNCHLRGRCIDGQCICDDGFTGEDCSQLACPSDCNDQGKCVNGVCICFE
Sbjct: 181 KGPNCSEPECPGNCHLRGRCIDGQCICDDGFTGEDCSQLACPSDCNDQGKCVNGVCICFE 240
Query: 241 GYAGADCSREICPVPCSEEHGTCVDGLCVCHDGFAGDDCNKPLCLNNCYNRGRCVENECV 300
GYAGADCSREICPVPCSEEHGTCVDGLCVCHDGFAGDDCNKPLCLNNCYNRGRCVENECV
Sbjct: 241 GYAGADCSREICPVPCSEEHGTCVDGLCVCHDGFAGDDCNKPLCLNNCYNRGRCVENECV 300
Query: 301 CDEGFTGEDCSELICPNDCFDRGRCINGTCYCEEGFTGEDCGKPTCPHACHTQGRCEEGQ 360
CDEGFTGEDCSELICPNDCFDRGRCINGTCYCEEGFTGEDCGKPTCPHACHTQGRCEEGQ
Sbjct: 301 CDEGFTGEDCSELICPNDCFDRGRCINGTCYCEEGFTGEDCGKPTCPHACHTQGRCEEGQ 360
Query: 361 CVCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECDDGFTGADCGELKCPNGCSGHGRCVN 420
CVCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECDDGFTGADCGELKCPNGCSGHGRCVN
Sbjct: 361 CVCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECDDGFTGADCGELKCPNGCSGHGRCVN 420
Query: 421 GQCVCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCEQGFKGYDCSDMSCPNDCHQHGRC 480
GQCVCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCEQGFKGYDCSDMSCPNDCHQHGRC
Sbjct: 421 GQCVCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCEQGFKGYDCSDMSCPNDCHQHGRC 480
Query: 481 VNGMCVCDDGYTGEDCRDRQCPRDCSNRGLCVDGQCVCEDGFTGPDCAELSCPNDCHGQG 540
VNGMCVCDDGYTGEDCRDRQCPRDCSNRGLCVDGQCVCEDGFTGPDCAELSCPNDCHGQG
Sbjct: 481 VNGMCVCDDGYTGEDCRDRQCPRDCSNRGLCVDGQCVCEDGFTGPDCAELSCPNDCHGQG 540
Query: 541 RCVNGQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLDCGQHSCPSDCNN 600
RCVNGQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLDCGQHSCPSDCNN
Sbjct: 541 RCVNGQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLDCGQHSCPSDCNN 600
Query: 601 LGQCVSGRCICNEGYSGEDCSEVSPPKDLVVTEVTEETVNLAWDNEMRVTEYLVVYTPTH 660
LGQCVSGRCICNEGYSGEDCSEVSPPKDLVVTEVTEETVNLAWDNEMRVTEYLVVYTPTH
Sbjct: 601 LGQCVSGRCICNEGYSGEDCSEVSPPKDLVVTEVTEETVNLAWDNEMRVTEYLVVYTPTH 660
Query: 661 EGGLEMQFRVPGDQTSTIIQELEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKF 720
EGGLEMQFRVPGDQTSTIIQELEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKF
Sbjct: 661 EGGLEMQFRVPGDQTSTIIQELEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKF 720
Query: 721 KSIKETSVEVEWDPLDIAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYE 780
KSIKETSVEVEWDPLDIAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYE
Sbjct: 721 KSIKETSVEVEWDPLDIAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYE 780
Query: 781 ISLHIVKNNTRGPGLKRVTTTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIK 840
ISLHIVKNNTRGPGLKRVTTTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIK
Sbjct: 781 ISLHIVKNNTRGPGLKRVTTTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIK 840
Query: 841 DVPGDRTTIDLTEDENQYSIGNLKPDTEYEVSLISRRGDMSSNPAKETFTTGLDAPRNLR 900
DVPGDRTTIDLTEDENQYSIGNLKPDTEYEVSLISRRGDMSSNPAKETFTTGLDAPRNLR
Sbjct: 841 DVPGDRTTIDLTEDENQYSIGNLKPDTEYEVSLISRRGDMSSNPAKETFTTGLDAPRNLR 900
Query: 901 RVSQTDNSITLEWRNGKAAIDSYRIKYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTE 960
RVSQTDNSITLEWRNGKAAIDSYRIKYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTE
Sbjct: 901 RVSQTDNSITLEWRNGKAAIDSYRIKYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTE 960
Query: 961 YGIGVSAVKEDKESNPATINAATELDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYS 1020
YGIGVSAVKEDKESNPATINAATELDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYS
Sbjct: 961 YGIGVSAVKEDKESNPATINAATELDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYS 1020
Query: 1021 LPTGQWVGVQLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTEQAPELENL 1080
LPTGQWVGVQLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTEQAPELENL
Sbjct: 1021 LPTGQWVGVQLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTEQAPELENL 1080
Query: 1081 TVTEVGWDGLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPY 1140
TVTEVGWDGLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPY
Sbjct: 1081 TVTEVGWDGLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPY 1140
Query: 1141 TVSIYGVIQGYRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQ 1200
TVSIYGVIQGYRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQ
Sbjct: 1141 TVSIYGVIQGYRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQ 1200
Query: 1201 EADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLTEEVPDMG 1260
EADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLTEEVPDMG
Sbjct: 1201 EADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLTEEVPDMG 1260
Query: 1261 NLTVTEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGT 1320
NLTVTEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGT
Sbjct: 1261 NLTVTEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGT 1320
Query: 1321 PYTVTLHGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQ 1380
PYTVTLHGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQ
Sbjct: 1321 PYTVTLHGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQ 1380
Query: 1381 VQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEASTAKEPE 1440
VQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEASTAKEPE
Sbjct: 1381 VQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEASTAKEPE 1440
Query: 1441 IGNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTAHISGLPP 1500
IGNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTAHISGLPP
Sbjct: 1441 IGNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTAHISGLPP 1500
Query: 1501 STDFIVYLSGLAPSIRTKTISATATTEALPLLENLTISDINPYGFTVSWMASENAFDSFL 1560
STDFIVYLSGLAPSIRTKTISATATTEALPLLENLTISDINPYGFTVSWMASENAFDSFL
Sbjct: 1501 STDFIVYLSGLAPSIRTKTISATATTEALPLLENLTISDINPYGFTVSWMASENAFDSFL 1560
Query: 1561 VTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFTQGHQTKPLRAEIVTEAE 1620
VTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFTQGHQTKPLRAEIVTEAE
Sbjct: 1561 VTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFTQGHQTKPLRAEIVTEAE 1620
Query: 1621 PEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQSEPLEITLLAPERTRDITGL 1680
PEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQSEPLEITLLAPERTRDITGL
Sbjct: 1621 PEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQSEPLEITLLAPERTRDITGL 1680
Query: 1681 REATEYEIELYGISKGRRSQTVSAIATTAMGSPKEVIFSDITENSATVSWRAPTAQVESF 1740
REATEYEIELYGISKGRRSQTVSAIATTAMGSPKEVIFSDITENSATVSWRAPTAQVESF
Sbjct: 1681 REATEYEIELYGISKGRRSQTVSAIATTAMGSPKEVIFSDITENSATVSWRAPTAQVESF 1740
Query: 1741 RITYVPITGGTPSMVTVDGTKTQTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTTALD 1800
RITYVPITGGTPSMVTVDGTKTQTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTTALD
Sbjct: 1741 RITYVPITGGTPSMVTVDGTKTQTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTTALD 1800
Query: 1801 GPSGLVTANITDSEALARWQPAIATVDSYVISYTGEKVPEITRTVSGNTVEYALTDLEPA 1860
GPSGLVTANITDSEALARWQPAIATVDSYVISYTGEKVPEITRTVSGNTVEYALTDLEPA
Sbjct: 1801 GPSGLVTANITDSEALARWQPAIATVDSYVISYTGEKVPEITRTVSGNTVEYALTDLEPA 1860
Query: 1861 TEYTLRIFAEKGPQKSSTITAKFTTDLDSPRDLTATEVQSETALLTWRPPRASVTGYLLV 1920
TEYTLRIFAEKGPQKSSTITAKFTTDLDSPRDLTATEVQSETALLTWRPPRASVTGYLLV
Sbjct: 1861 TEYTLRIFAEKGPQKSSTITAKFTTDLDSPRDLTATEVQSETALLTWRPPRASVTGYLLV 1920
Query: 1921 YESVDGTVKEVIVGPDTTSYSLADLSPSTHYTAKIQALNGPLRSNMIQTIFTTIGLLYPF 1980
YESVDGTVKEVIVGPDTTSYSLADLSPSTHYTAKIQALNGPLRSNMIQTIFTTIGLLYPF
Sbjct: 1921 YESVDGTVKEVIVGPDTTSYSLADLSPSTHYTAKIQALNGPLRSNMIQTIFTTIGLLYPF 1980
Query: 1981 PKDCSQAMLNGDTTSGLYTIYLNGDKAEALEVFCDMTSDGGGWIVFLRRKNGRENFYQNW 2040
PKDCSQAMLNGDTTSGLYTIYLNGDKAEALEVFCDMTSDGGGWIVFLRRKNGRENFYQNW
Sbjct: 1981 PKDCSQAMLNGDTTSGLYTIYLNGDKAEALEVFCDMTSDGGGWIVFLRRKNGRENFYQNW 2040
Query: 2041 KAYAAGFGDRREEFWLGLDNLNKITAQGQYELRVDLRDHGETAFAVYDKFSVGDAKTRYK 2100
KAYAAGFGDRREEFWLGLDNLNKITAQGQYELRVDLRDHGETAFAVYDKFSVGDAKTRYK
Sbjct: 2041 KAYAAGFGDRREEFWLGLDNLNKITAQGQYELRVDLRDHGETAFAVYDKFSVGDAKTRYK 2100
Query: 2101 LKVEGYSGTAGDSMAYHNGRSFSTFDKDTDSAITNCALSYKGAFWYRNCHRVNLMGRYGD 2160
LKVEGYSGTAGDSMAYHNGRSFSTFDKDTDSAITNCALSYKGAFWYRNCHRVNLMGRYGD
Sbjct: 2101 LKVEGYSGTAGDSMAYHNGRSFSTFDKDTDSAITNCALSYKGAFWYRNCHRVNLMGRYGD 2160
Query: 2161 NNHSQGVNWFHWKGHEHSIQFAEMKLRPSNFRNLEGRRKRA 2201
NNHSQGVNWFHWKGHEHSIQFAEMKLRPSNFRNLEGRRKRA
Sbjct: 2161 NNHSQGVNWFHWKGHEHSIQFAEMKLRPSNFRNLEGRRKRA 2201
>gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens]
Length = 4242
Score = 937 bits (2421), Expect = 0.0
Identities = 608/2059 (29%), Positives = 916/2059 (44%), Gaps = 277/2059 (13%)
Query: 161 CSGRGNFSTEGCGCVCEPGWKGPNCSEPECPGNCHLRGRCIDGQCICDDGFTGEDCSQLA 220
CS RG EG CVC+PG+ G +C CP C RGRC +G+C+C+ G+TGEDC +
Sbjct: 253 CSQRGR--CEGGRCVCDPGYTGDDCGMRSCPRGCSQRGRCENGRCVCNPGYTGEDCGVRS 310
Query: 221 CPSDCNDQGKCVNGVCICFEGYAGADCSREICPVPCSEEHGTCVDGLCVCHDGFAGDDCN 280
CP C+ +G+C +G C+C GY G DC CP C E G CVDG CVC G+ G+DC+
Sbjct: 311 CPRGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEG-GRCVDGRCVCWPGYTGEDCS 369
Query: 281 KPLCLNNCYNRGRCVENECVCDEGFTGEDCSELICPNDCFDRGRCINGTCYCEEGFTGED 340
C +C RGRC + EC+CD G++G+DC CP DC RGRC +G C C G+TG D
Sbjct: 370 TRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQRGRCEDGRCVCWPGYTGTD 429
Query: 341 CGKPTCPHACHTQGRCEEGQCVCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECDDGFTG 400
CG CP C +GRCE G CVC+ G++G DC + CP DC RGRC GRC C G+TG
Sbjct: 430 CGSRACPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWPGYTG 489
Query: 401 ADCGELKCPNGCSGHGRCVNGQCVCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCEQGF 460
DCG CP C G GRCV+G+CVC+ G+TGEDC RCP DC G C +G CVC+ G+
Sbjct: 490 RDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGY 549
Query: 461 KGYDCSDMSCPNDCHQHGRCVNGMCVCDDGYTGEDCRDRQCPRDCSNRGLCVDGQCVCED 520
G DCS SCP C G+C++G CVC+DGY+GEDC RQCP DCS G+C DG C+C +
Sbjct: 550 SGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWE 609
Query: 521 GFTGPDCAELSCPNDCHGQGRCVNGQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCIC 580
G+ DC+ +CP++CHG+GRC G+C+C G+ G C + CP+DC G+GRCV G C+C
Sbjct: 610 GYVSEDCSIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLC 669
Query: 581 HEGFTGLDCGQ------------------------------------HSCPSDCNNLGQC 604
H G+ G DCGQ +CP DC G+C
Sbjct: 670 HVGYGGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPGDCRGRGEC 729
Query: 605 VSGRCICNEGYSGEDCSEVSPPKDLVVTEVTEE-TVNLAWDNEM-RVTEYLVVYTPTHEG 662
G C+C +GY+GEDC E P + + + EE TV W V Y + + PT EG
Sbjct: 730 HDGSCVCKDGYAGEDCGEEVPTIEGMRMHLLEETTVRTEWTPAPGPVDAYEIQFIPTTEG 789
Query: 663 GL-EMQFRVPGDQTSTIIQELEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFK 721
RVP ++ + L PG EY + V A+ +P S + T + P+ L+
Sbjct: 790 ASPPFTARVPSSASAYDQRGLAPGQEYQVTVRALRGTSWGLPASKTITTMIDGPQDLRVV 849
Query: 722 SIKETSVEVEWDPLDIAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEI 781
++ T++E+ W + + + + + + + + T L PG EY +
Sbjct: 850 AVTPTTLELGWLRPQAEVDRFVVSYVSAGNQ---RVRLEVPPEADGTLLTDLMPGVEYVV 906
Query: 782 SLHI-----------VKNNTRGPGLKRVTTTRLDAPS---------------------QI 809
++ V+ NT L + TT PS ++
Sbjct: 907 TVTAERGRAVSYPASVRANTGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRPQELGEL 966
Query: 810 EVKDVTDTTAL-ITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQYSIGNLKPDTE 868
V +T L + W +L + + PG + L D Q + P T
Sbjct: 967 RVLGRDETGRLRVVWTAQPDTFAYFQLRMRVPEGPGAHEEV-LPGDVRQALVPPPPPGTP 1025
Query: 869 YEVSL------------ISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSITLEWRNG 916
YE+SL I +G M + K ++G L +T +S+ L W
Sbjct: 1026 YELSLHGVPPGGKPSDPIIYQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVP 1085
Query: 917 KAAIDSYRIKYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKEDKESNP 976
+ DS+ I+Y G + V + +T L PG +Y + K P
Sbjct: 1086 EGEFDSFVIQYKDRDG----QPQVVPVEGPQRSAVITSLDPGRKYKFVLYGFVGKKRHGP 1141
Query: 977 ATINAA------TELDTPK---DLQVSETAETSLTLLWKTPLAKFDRYRLNYSLPTGQWV 1027
A TP +L V++ SL L W P +FD + + Y G+
Sbjct: 1142 LVAEAKILPQSDPSPGTPPHLGNLWVTDPTPDSLHLSWTVPEGQFDTFMVQYRDRDGRPQ 1201
Query: 1028 GVQLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTE-------------QA 1074
V + S+V+ L+P +Y L + + P +T +
Sbjct: 1202 VVPVEGPERSFVVSSLDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQ 1261
Query: 1075 PELENLTVTEVGWDGLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGL 1134
P L LTVT V D LRL+WT A ++ F++Q ++A A + V G V +PGL
Sbjct: 1262 PLLGELTVTGVTPDSLRLSWTVAQGPFDSFMVQYKDAQGQPQA--VPVAGDENEVTVPGL 1319
Query: 1135 KAATPYTVSIYGVIQGYRTPVLSAEASTG----------------------ETPNLGEVV 1172
Y +++YG+ R S A T E P LGE+
Sbjct: 1320 DPDRKYKMNLYGLRGRQRVGPESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELT 1379
Query: 1173 VAEVGWDALKLNWTAPEGAYEYFFIQVQEADTVEAAQNLTVPGGLRSTDLPGLKAATHYT 1232
V D+L L WT P+G+++ F +Q ++ D A + V G + GL+ Y
Sbjct: 1380 VTGSSPDSLSLFWTVPQGSFDSFTVQYKDRDGRPRA--VRVGGKESEVTVGGLEPGHKYK 1437
Query: 1233 ITIRGVTQDFSTTPLSVEVLT----EEVPD---------MGNLTVTEVSWDALRLNWTTP 1279
+ + G+ + P+S +T EE P +G LTVT+V+ +++ L+WT P
Sbjct: 1438 MHLYGLHEGQRVGPVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVP 1497
Query: 1280 DGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTVTLHGEVRGHSTRPLA 1339
+G +D F +Q ++ D + + V R + + L Y + ++G G PL+
Sbjct: 1498 EGQFDSFIVQYKDKDGQPQV--VPVAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLS 1555
Query: 1340 VEVVTEDL--------------PQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQVQEVN 1385
V +VT L P+LG+L V+++ D + L+WT + ++ FV+Q ++
Sbjct: 1556 VVIVTAPLPPAPATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQYKD-- 1613
Query: 1386 KVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEASTAKE------- 1438
+ Q + + R V IP LE + Y+ ++G+ G R +S EA T
Sbjct: 1614 RDGQPQVVPVAADQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGA 1673
Query: 1439 -PEIGNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTAHISG 1497
P +G L V+D TP+S LSW +G F++F ++ D + + G ER+ ++
Sbjct: 1674 PPRLGELWVTDPTPDSLRLSWTVPEGQFDSFVVQFKDKD---GPQVVPVEGHERSVTVTP 1730
Query: 1498 LPPSTDFIVYLSGLAPSIRTKTISATATTEALPLL--------------ENLTISDINPY 1543
L + L GL R ++A TTEA + E L ++ +
Sbjct: 1731 LDAGRKYRFLLYGLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQN 1790
Query: 1544 GFTVSWMASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFT 1603
+SW E FDSF+V D PQ + G+ R++ + GL Y++++ G
Sbjct: 1791 SVGLSWTVPEGQFDSFVVQYKDRDG--QPQVVPVEGSLREVSVPGLDPAHRYKLLLYGLH 1848
Query: 1604 QGHQTKPLRAEIVTEA----------------EPEVDNLLVSDATPDGFRLSWTADEGVF 1647
G + P+ A +T EP + L V +AT LSW EG F
Sbjct: 1849 HGKRVGPISAVAITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEF 1908
Query: 1648 DNFVLKIRDTKKQSEPLEITLLAPERTRDIT--GLREATEYEIELYGISKGRRSQTVSAI 1705
D+F ++ D Q L++ + +R DIT GL Y + LYG S G+ V
Sbjct: 1909 DSFEIQYTDRDGQ---LQMVRIGGDR-NDITLSGLESDHRYLVTLYGFSDGKHVGPVHVE 1964
Query: 1706 ATTAMGSPK------------------EVIFSDITENSATVSWRAPTAQVESFRITYVPI 1747
A T K E+ +D T +S ++SW P Q + F + Y
Sbjct: 1965 ALTVPEEEKPSEPPTATPEPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDHFLVQY-RN 2023
Query: 1748 TGGTPSMVTVDGTKTQTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTTA--------- 1798
G P V V G + + L P +Y +++ G + PVS TA
Sbjct: 2024 GDGQPKAVRVPGHEEGVTISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPT 2083
Query: 1799 ---LDGPSG---------LVTANITDSEALARWQPAIATVDSYVISYTG-EKVPEITRTV 1845
++ P VT + DS +L+ W DS+ + Y + P++ R V
Sbjct: 2084 EPSMEAPEPAEEPLLGELTVTGSSPDSLSLS-WTVPQGRFDSFTVQYKDRDGRPQVVR-V 2141
Query: 1846 SGNTVEYALTDLEPATEYTLRIFA-----EKGPQKSSTITAKFTTDLDSP------RDLT 1894
G E + LEP +Y + ++ GP + +TA D+P +T
Sbjct: 2142 GGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQMT 2201
Query: 1895 ATEVQSETALLTWRPPRASVTGYLLVYESVDGTVKEVIVGPDTTSYSLADLSPSTHYTAK 1954
++ S++ L+W P +L+ +++ DG K V V +++ L P Y
Sbjct: 2202 VRDITSDSLSLSWTVPEGQFDHFLVQFKNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMN 2261
Query: 1955 IQALNGPLRSNMIQTIFTT 1973
+ +G R + + T
Sbjct: 2262 LYGFHGGQRVGPVSAVGLT 2280
Score = 780 bits (2013), Expect = 0.0
Identities = 544/1736 (31%), Positives = 835/1736 (48%), Gaps = 189/1736 (10%)
Query: 628 DLVVTEVTEETVNLAWD-NEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTIIQELEPGV 686
+L VT + ++++L+W + R + V Y G RV G ++ ++ LEPG
Sbjct: 2527 ELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKD--RDGRPQAVRVGGQESKVTVRGLEPGR 2584
Query: 687 EYFIRVFAILENKKSIPVSA------------RVATYLPAPE------GLKFKSIKETSV 728
+Y + ++ + E ++ PVSA V T P P L S+
Sbjct: 2585 KYKMHLYGLHEGRRLGPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSL 2644
Query: 729 EVEWDPLDIAFETWEIIFRNMNKEDEGEITKSLRRP--ETSYRQTGLAPGQEYEISLHIV 786
+ W + F+ + + +RN + + K++R P E +GL P +Y+++L+
Sbjct: 2645 SLSWTVPEGQFDHFLVQYRNGDGQP-----KAVRVPGHEDGVTISGLEPDHKYKMNLYGF 2699
Query: 787 KNNTR-GP-GLKRVTTTRLDAPSQIEVK-------------DVTDT-----TALITWFKP 826
R GP + VT + PS E+ ++T T + ++W P
Sbjct: 2700 HGGQRVGPISVIGVTAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIP 2759
Query: 827 LAEIDGIELTYGIKDVPGDRTTIDLTEDENQYSIGNLKPDTEYEVSLISRRGDMSSNPAK 886
D + Y KD G + + +E++ ++G L+P +Y++ L P
Sbjct: 2760 QGHFDSFTVQY--KDRDGRPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVS 2817
Query: 887 ETFTTGLDA------------PRNLRRVSQ------TDNSITLEWRNGKAAIDSYRIKYA 928
T +A P N R+ + T +S++L W + D + ++Y
Sbjct: 2818 TVGVTEDEAETTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYR 2877
Query: 929 PISGGDHAEVDVPKSQQATT----------KTTLTGLRPGTEYG-IGVSAVKEDKESNPA 977
G V VP + T K L G G G I V V +E PA
Sbjct: 2878 N-GDGQPKVVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPA 2936
Query: 978 TINAATELDTPKD------LQVSETAETSLTLLWKTPLAKFDRYRLNYSLPTGQWVGVQL 1031
+TE P + L V+ ++ SL+L W P +FD + + Y G+ V++
Sbjct: 2937 PTEPSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGRFDSFTVQYKDRDGRPQVVRV 2996
Query: 1032 PRNTTSYVLRGLEPGQEYNV-LLTAEKGRHKSKPARV-------KASTEQA--------- 1074
+ + GLEPG +Y + L +G+ + V +A T QA
Sbjct: 2997 RGEESEVTVGGLEPGCKYKMHLYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPP 3056
Query: 1075 --PELENLTVTEVGWDGLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIP 1132
P L LTVT+ D L L+W + ++HF++Q + + A + VPG V I
Sbjct: 3057 IKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQPKA--VRVPGHEDGVTIS 3114
Query: 1133 GLKAATPYTVSIYGVIQGYRTPVLSA------------EASTG-----ETPNLGEVVVAE 1175
GL+ Y +++YG G R +SA E ST E P LGE+ V
Sbjct: 3115 GLEPDHKYKMNLYGFHGGQRVGPVSAIGVTEEETPSPTEPSTEAPEAPEEPLLGELTVTG 3174
Query: 1176 VGWDALKLNWTAPEGAYEYFFIQVQEADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITI 1235
D+L L+WT P+G ++ F +Q ++ D Q + V G + GL+ Y + +
Sbjct: 3175 SSPDSLSLSWTVPQGRFDSFTVQYKDRDG--QPQVVRVRGEESEVTVGGLEPGRKYKMHL 3232
Query: 1236 RGVTQDFSTTPLSVEVLTEEVPD-------MGNLTVTEVSWDALRLNWTTPDGTYDQFTI 1288
G+ + P+S +T +P +G L V V+ D++ L+WT G +D F +
Sbjct: 3233 YGLHEGQRVGPVSTVGITAPLPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQGPFDSFLV 3292
Query: 1289 QVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTVTLHGEVRGHSTRPLAVEVVT---- 1344
Q ++A +A + V G LR++ + GL Y L G G P+ VE T
Sbjct: 3293 QYRDAQGQPQA--VPVSGDLRAVAVSGLDPARKYKFLLFGLQNGKRHGPVPVEARTAPDT 3350
Query: 1345 EDLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQVQEVNKVEAAQNLTLPGSLRAVDI 1404
+ P+LG+L V++ D + L+WT + ++ FV+Q ++ K Q + + + R V +
Sbjct: 3351 KPSPRLGELTVTDATPDSVGLSWTVPEGEFDSFVVQYKD--KDGRLQVVPVAANQREVTV 3408
Query: 1405 PGLEAATPYRVSIYGVIRGYRTPVLSAEASTA---KE--PEIGNLNVSDITPESFNLSWM 1459
GLE + YR +YG+ R +SA+++TA KE P +G L V++ T S LSW
Sbjct: 3409 QGLEPSRKYRFLLYGLSGRKRLGPISADSTTAPLEKELPPHLGELTVAEETSSSLRLSWT 3468
Query: 1460 ATDGIFETFTIEIIDSNRLLETVEYNISGAERTAHISGLPPSTDFIVYLSGLAPSIRTKT 1519
G F++F ++ D++ V ++ +RT + L P + L GL R
Sbjct: 3469 VAQGPFDSFVVQYRDTDGQPRAVP--VAADQRTVTVEDLEPGKKYKFLLYGLLGGKRLGP 3526
Query: 1520 ISA---TATTEALPLLEN---------------LTISDINPYGFTVSWMASENAFDSFLV 1561
+SA TA E P E LT++D P +SW ++ FDSF+V
Sbjct: 3527 VSALGMTAPEEDTPAPELAPEAPEPPEEPRLGVLTVTDTTPDSMRLSWSVAQGPFDSFVV 3586
Query: 1562 TVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFTQGHQTKPLRAEIVT---- 1617
D+ PQ + G Q K+ + GL Y ++ G +G + PL AE T
Sbjct: 3587 QYEDTNG--QPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGKRLGPLSAEGTTGLAP 3644
Query: 1618 ------EAEPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQS-EP-----LE 1665
E+ P + L V+D T RL+W A G FD+F+L+ + EP L+
Sbjct: 3645 AGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTLEPHPRPLLQ 3704
Query: 1666 ITLLAP--ERTRDITGLREATEYEIELYGISKGRRSQTVSAIATT---AMGSPKEVIFSD 1720
L+ P + + LR T Y + LYG+ ++ ++ A T + SP+++ FS+
Sbjct: 3705 RELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQFSE 3764
Query: 1721 ITENSATVSWRAPTAQVESFRITYVPITGGTPSMVTVDGTKTQTRLVKLIPGVEYLVSII 1780
I E SA V+W P ++ +SF+++Y GG P V VDG +L LIPG Y V+++
Sbjct: 3765 IRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQKLQGLIPGARYEVTVV 3824
Query: 1781 AMKGFEESEPVSGSFTTALDGPSGLVTANITDSEALARWQPAIATVDSYVISYTGEKVPE 1840
+++GFEESEP++G TT DGP+ L N+T+ A+ W+P VD+Y + T P
Sbjct: 3825 SVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNPVDTYDVQVTAPGAPP 3884
Query: 1841 ITRTVSGNTVEYALTDLEPATEYTLRIFAEKGPQKSSTITAKFTTDLDSPRDLTATEVQS 1900
+ G+ V+Y L DL T YT + +GP +S + FTT L++PRDL A EV
Sbjct: 3885 LQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTTGLEAPRDLEAKEVTP 3944
Query: 1901 ETALLTWRPPRASVTGYLLVYESVDGTVKEVIVGPDTTSYSLADLSPSTHYTAKIQALNG 1960
TALLTW P GYLL + + G +E+++ TS+ L L PST Y A++QA+ G
Sbjct: 3945 RTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLGLFPSTSYNARLQAMWG 4004
Query: 1961 PLRSNMIQTIFTTIGLLYPFPKDCSQAMLNGDTTSGLYTIYLNGDKAEALEVFCDMTSDG 2020
+ T FTT GL PFP+DC + M NG S TI+LNG++ L VFCDM +DG
Sbjct: 4005 QSLLPPVSTSFTTGGLRIPFPRDCGEEMQNGAGASRTSTIFLNGNRERPLNVFCDMETDG 4064
Query: 2021 GGWIVFLRRKNGRENFYQNWKAYAAGFGDRREEFWLGLDNLNKITAQGQYELRVDLRDHG 2080
GGW+VF RR +G+ +F+++W+ YA GFG+ EFWLG + L+ +T G Y +RVDLR
Sbjct: 4065 GGWLVFQRRMDGQTDFWRDWEDYAHGFGNISGEFWLGNEALHSLTQAGDYSMRVDLRAGD 4124
Query: 2081 ETAFAVYDKFSVGDAKTRYKLKVEGYSGTAGDSMAYHNGRSFSTFDKDTDSAITNCALSY 2140
E FA YD F V A Y+L +EGY GTAGDSM+YH+G FS D+D +S + +CA+SY
Sbjct: 4125 EAVFAQYDSFHVDSAAEYYRLHLEGYHGTAGDSMSYHSGSVFSARDRDPNSLLISCAVSY 4184
Query: 2141 KGAFWYRNCHRVNLMGRYGDNNHSQGVNWFHWKGHEHSIQFAEMKLRPSNFRNLEG 2196
+GA+WYRNCH NL G YG QGV+W+HWKG E S+ F EMKLRP NFR+ G
Sbjct: 4185 RGAWWYRNCHYANLNGLYGSTVDHQGVSWYHWKGFEFSVPFTEMKLRPRNFRSPAG 4240
Score = 659 bits (1699), Expect = 0.0
Identities = 289/632 (45%), Positives = 360/632 (56%), Gaps = 90/632 (14%)
Query: 83 PSESFQEHTVDG-ENQIVFTHRINIP-RRACGC-------AAAPDVKELLSRLEELENLV 133
PS EHTV+G E Q+VFTHRIN+P CGC A +V+ L RLE LE LV
Sbjct: 55 PSSQLYEHTVEGGEKQVVFTHRINLPPSTGCGCPPGTEPPVLASEVQALRVRLEILEELV 114
Query: 134 SSLREQCTAGAGCC---LQPATGRLDTRPFCSGRGNFSTEGCGCVCEPGWKGPNCSEP-- 188
L+EQCT G CC Q TG+ D R CS G F C C CEPGW GP CS+P
Sbjct: 115 KGLKEQCTGG--CCPASAQAGTGQTDVRTLCSLHGVFDLSRCTCSCEPGWGGPTCSDPTD 172
Query: 189 -------------ECPGNCHLRGRCIDGQCICDDGFTGEDCSQLACPSDCNDQGKCVNGV 235
CP +C+ +GRC+ G+C+C G+TG C +CP DC +G+CV GV
Sbjct: 173 AEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSCGWPSCPGDCQGRGRCVQGV 232
Query: 236 CICFEGYAGADCSREICPVPCSE------------------------------EHGTCVD 265
C+C G++G DCS+ CP CS+ + G C +
Sbjct: 233 CVCRAGFSGPDCSQRSCPRGCSQRGRCEGGRCVCDPGYTGDDCGMRSCPRGCSQRGRCEN 292
Query: 266 GLCVCHDGFAGDDCNKPLCLNNCYNRGRCVENECVCDEGFTGEDCSELICPNDCFDRGRC 325
G CVC+ G+ G+DC C C RGRC + CVCD G+TGEDC CP DC + GRC
Sbjct: 293 GRCVCNPGYTGEDCGVRSCPRGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGGRC 352
Query: 326 INGTCYCEEGFTGEDCGKPTCPHACHTQGRCEEGQCVCDEGFAGVDCSEKRCPADCHNRG 385
++G C C G+TGEDC TCP C +GRCE+G+C+CD G++G DC + CP DC+ RG
Sbjct: 353 VDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQRG 412
Query: 386 RCVDGRCECDDGFTGADCGELKCPNGCSGHGRCVNGQCVCDEGYTGE------------- 432
RC DGRC C G+TG DCG CP C G GRC NG CVC+ GY+GE
Sbjct: 413 RCEDGRCVCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRG 472
Query: 433 ------------------DCSQLRCPNDCHSRGRCVEGKCVCEQGFKGYDCSDMSCPNDC 474
DC CP DC RGRCV+G+CVC GF G DC CP DC
Sbjct: 473 RGRCESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDC 532
Query: 475 HQHGRCVNGMCVCDDGYTGEDCRDRQCPRDCSNRGLCVDGQCVCEDGFTGPDCAELSCPN 534
HG C +G+CVCD GY+GEDC R CP C RG C+DG+CVCEDG++G DC CPN
Sbjct: 533 RGHGLCEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPN 592
Query: 535 DCHGQGRCVNGQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLDCGQHSC 594
DC G C +G C+C EG++ +DC + CPS+CHG+GRC +G+C+C G+TG C C
Sbjct: 593 DCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRMC 652
Query: 595 PSDCNNLGQCVSGRCICNEGYSGEDCSEVSPP 626
P+DC G+CV G C+C+ GY GEDC + PP
Sbjct: 653 PADCRGRGRCVQGVCLCHVGYGGEDCGQEEPP 684
Score = 395 bits (1014), Expect = e-109
Identities = 395/1631 (24%), Positives = 649/1631 (39%), Gaps = 307/1631 (18%)
Query: 618 EDCSEVSPPK-----DLVVTEVTEETVNLAWD-NEMRVTEYLVVYTPTHEGGLEMQFRVP 671
+D PPK +L VT VT+ +V L+W E + ++V Y G V
Sbjct: 1766 DDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPEGQFDSFVVQY--KDRDGQPQVVPVE 1823
Query: 672 GDQTSTIIQELEPGVEYFIRVFAILENKKSIPVSA-------------RVATYLPAPE-- 716
G + L+P Y + ++ + K+ P+SA A PAPE
Sbjct: 1824 GSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVAITAGREETETETTAPTPPAPEPH 1883
Query: 717 --GLKFKSIKETSVEVEWDPLDIAFETWEIIFRNMNKE--------DEGEITKSLRRPET 766
L + ++ + W + F+++EI + + + + D +IT S
Sbjct: 1884 LGELTVEEATSHTLHLSWMVTEGEFDSFEIQYTDRDGQLQMVRIGGDRNDITLS------ 1937
Query: 767 SYRQTGLAPGQEYEISLHIVKNNTR-GP-GLKRVTTTRLDAPS----------------Q 808
GL Y ++L+ + GP ++ +T + PS +
Sbjct: 1938 -----GLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSEPPTATPEPPIKPRLGE 1992
Query: 809 IEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQYSIGNLKPDTE 868
+ V D T + ++W P + D + Y ++ G + + E +I L+PD +
Sbjct: 1993 LTVTDATPDSLSLSWTVPEGQFDHFLVQY--RNGDGQPKAVRVPGHEEGVTISGLEPDHK 2050
Query: 869 YEVSLISRRGDMSSNPAKETFTT------------GLDAPR--------NLRRVSQTDNS 908
Y+++L G P T ++AP L + +S
Sbjct: 2051 YKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLLGELTVTGSSPDS 2110
Query: 909 ITLEWRNGKAAIDSYRIKYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAV 968
++L W + DS+ ++Y G V + ++ T+ GL PG +Y + + +
Sbjct: 2111 LSLSWTVPQGRFDSFTVQYKDRDG----RPQVVRVGGEESEVTVGGLEPGRKYKMHLYGL 2166
Query: 969 KEDKESNPATINAAT--ELDTPK---------DLQVSETAETSLTLLWKTPLAKFDRYRL 1017
E + P + T E ++P + V + SL+L W P +FD + +
Sbjct: 2167 HEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQMTVRDITSDSLSLSWTVPEGQFDHFLV 2226
Query: 1018 NYSLPTGQWVGVQLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPA------------ 1065
+ GQ V++P + + GLEP +Y + L G + P
Sbjct: 2227 QFKNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAVGLTAPGKDE 2286
Query: 1066 -RVKASTEQ-------APELENLTVTEVGWDGLRLNWTAADQAYEHFIIQVQEANKVEAA 1117
ASTE P LE LTVT+ D L L+WT + ++HF++Q + + A
Sbjct: 2287 EMAPASTEPPTPEPPIKPRLEELTVTDATPDSLSLSWTVPEGQFDHFLVQYKNGDGQPKA 2346
Query: 1118 RNLTVPGSLRAVDIPGLKAATPYTVSIYGVIQGYRTPVLSAEASTG-------------- 1163
VPG V I GL+ Y +++YG G R +SA T
Sbjct: 2347 TR--VPGHEDRVTISGLEPDNKYKMNLYGFHGGQRVGPVSAIGVTAAEEETPSPTEPSME 2404
Query: 1164 -----ETPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEAD------TVEAAQNLT 1212
E P LGE+ V D+L L+WT P+G ++ F +Q ++ D V ++
Sbjct: 2405 APEPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVRVGGEESEV 2464
Query: 1213 VPGGLRSTDLPGLKAATHY-------------TITIRGVTQDFSTTPLSVEVLTE----- 1254
GGL PG K H T+ + +D TP E TE
Sbjct: 2465 TVGGLE----PGRKYKMHLYGLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPP 2520
Query: 1255 EVPDMGNLTVTEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIP 1314
E P +G LTVT S D+L L+WT P G +D FT+Q ++ D +A + V G + +
Sbjct: 2521 EEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQA--VRVGGQESKVTVR 2578
Query: 1315 GLRAGTPYTVTLHGEVRGHSTRPLAVEVVTED-----------------LPQLGDLAVSE 1357
GL G Y + L+G G P++ VTED P+LG+L +++
Sbjct: 2579 GLEPGRKYKMHLYGLHEGRRLGPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTD 2638
Query: 1358 VGWDGLRLNWTAADNAYEHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSI 1417
D L L+WT + ++HF++Q + N + + +PG V I GLE Y++++
Sbjct: 2639 ATPDSLSLSWTVPEGQFDHFLVQYR--NGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNL 2696
Query: 1418 YGVIRGYRTPVLSAEASTA-------------------KEPEIGNLNVSDITPESFNLSW 1458
YG G R +S TA +EP +G L V+ +P+S +LSW
Sbjct: 2697 YGFHGGQRVGPISVIGVTAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSW 2756
Query: 1459 MATDGIFETFTIEIIDSNRLLETVEYNISGAERTAHISGLPPSTDFIVYLSGLAPSIRTK 1518
G F++FT++ D + + + + G E + GL P + ++L GL R
Sbjct: 2757 TIPQGHFDSFTVQYKDRDGRPQVM--RVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVG 2814
Query: 1519 TISATA-------TTEALPL----------LENLTISDINPYGFTVSWMASENAFDSFLV 1561
+S TT+A+P L LT++D P ++SWM E FD FLV
Sbjct: 2815 PVSTVGVTEDEAETTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLV 2874
Query: 1562 TVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFTQGHQTKPLRAEIVTEA-- 1619
+ P+ + G + + + GL Y++ + GF G + P+ VT A
Sbjct: 2875 QYRNGDG--QPKVVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEE 2932
Query: 1620 -----------------EPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQSE 1662
EP + L V+ ++PD LSWT +G FD+F ++ +D +
Sbjct: 2933 ETPAPTEPSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGRFDSFTVQYKD--RDGR 2990
Query: 1663 PLEITLLAPERTRDITGLREATEYEIELYGISKGRRSQTVSAIATTAMGSPK-------- 1714
P + + E + GL +Y++ LYG+ +G+R VSA+ TA PK
Sbjct: 2991 PQVVRVRGEESEVTVGGLEPGCKYKMHLYGLHEGQRVGPVSAVGVTA---PKDEAETTQA 3047
Query: 1715 ---------------EVIFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSMVTVDG 1759
E+ +D T +S ++SW P Q + F + Y G P V V G
Sbjct: 3048 VPTMTPEPPIKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQY-RNGDGQPKAVRVPG 3106
Query: 1760 TKTQTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTTALDGPSG--------------- 1804
+ + L P +Y +++ G + PVS T + PS
Sbjct: 3107 HEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAIGVTEEETPSPTEPSTEAPEAPEEPL 3166
Query: 1805 ----LVTANITDSEALARWQPAIATVDSYVISYTG-EKVPEITRTVSGNTVEYALTDLEP 1859
VT + DS +L+ W DS+ + Y + P++ R V G E + LEP
Sbjct: 3167 LGELTVTGSSPDSLSLS-WTVPQGRFDSFTVQYKDRDGQPQVVR-VRGEESEVTVGGLEP 3224
Query: 1860 ATEYTLRIFA-----EKGPQKSSTITAKFTTDLD-SPR--DLTATEVQSETALLTWRPPR 1911
+Y + ++ GP + ITA T L PR +L V S++ L+W +
Sbjct: 3225 GRKYKMHLYGLHEGQRVGPVSTVGITAPLPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQ 3284
Query: 1912 ASVTGYLLVYESVDGTVKEVIVGPDTTSYSLADLSPSTHYTAKIQALNGPLRSNMIQTIF 1971
+L+ Y G + V V D + +++ L P+ Y + L R +
Sbjct: 3285 GPFDSFLVQYRDAQGQPQAVPVSGDLRAVAVSGLDPARKYKFLLFGLQNGKRHGPVPVEA 3344
Query: 1972 TTIGLLYPFPK 1982
T P P+
Sbjct: 3345 RTAPDTKPSPR 3355
Score = 382 bits (980), Expect = e-105
Identities = 390/1586 (24%), Positives = 639/1586 (40%), Gaps = 271/1586 (17%)
Query: 623 VSPPKDLVVTEVTEETVNLAWDN-EMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTIIQE 681
+ P+DL V VT T+ L W + V ++V Y G ++ VP + T++ +
Sbjct: 840 IDGPQDLRVVAVTPTTLELGWLRPQAEVDRFVVSYVSA--GNQRVRLEVPPEADGTLLTD 897
Query: 682 LEPGVEYFIRVFAILENKKSIPVSARV-----------ATYLPAPEG------------- 717
L PGVEY + V A S P S R T P P G
Sbjct: 898 LMPGVEYVVTVTAERGRAVSYPASVRANTGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQ 957
Query: 718 --------LKFKSIKETS-VEVEWDPLDIAFETWEIIFR---NMNKEDE---GEITKSLR 762
L+ ET + V W F +++ R +E G++ ++L
Sbjct: 958 QRPQELGELRVLGRDETGRLRVVWTAQPDTFAYFQLRMRVPEGPGAHEEVLPGDVRQALV 1017
Query: 763 RPETSYRQTGLAPGQEYEISLH----------------IVKNNTRGPGLKRVTTTRLDAP 806
P PG YE+SLH I+ + PG K RL
Sbjct: 1018 PPPP--------PGTPYELSLHGVPPGGKPSDPIIYQGIMDKDEEKPG-KSSGPPRL--- 1065
Query: 807 SQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQYSIGNLKPD 866
++ V D T + L+ W P E D + Y KD G + + + I +L P
Sbjct: 1066 GELTVTDRTSDSLLLRWTVPEGEFDSFVIQY--KDRDGQPQVVPVEGPQRSAVITSLDPG 1123
Query: 867 TEYEVSLISRRGDMSSNP--AKETFTTGLD----APRNLRRVSQTD---NSITLEWRNGK 917
+Y+ L G P A+ D P +L + TD +S+ L W +
Sbjct: 1124 RKYKFVLYGFVGKKRHGPLVAEAKILPQSDPSPGTPPHLGNLWVTDPTPDSLHLSWTVPE 1183
Query: 918 AAIDSYRIKY---------APISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYG---IGV 965
D++ ++Y P+ G + + V + TL G+ YG
Sbjct: 1184 GQFDTFMVQYRDRDGRPQVVPVEGPERSFVVSSLDPDHKYRFTLFGIANKKRYGPLTADG 1243
Query: 966 SAVKEDKESNPATINAATELDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYSLPTGQ 1025
+ E KE P E +L V+ SL L W FD + + Y GQ
Sbjct: 1244 TTAPERKEEPPRP--EFLEQPLLGELTVTGVTPDSLRLSWTVAQGPFDSFMVQYKDAQGQ 1301
Query: 1026 WVGVQLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKAST-------------- 1071
V + + + GL+P ++Y + L +GR + P V A T
Sbjct: 1302 PQAVPVAGDENEVTVPGLDPDRKYKMNLYGLRGRQRVGPESVVAKTAPQEDVDETPSPTE 1361
Query: 1072 --EQAPE------LENLTVTEVGWDGLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVP 1123
+APE L LTVT D L L WT +++ F +Q ++ + R + V
Sbjct: 1362 LGTEAPESPEEPLLGELTVTGSSPDSLSLFWTVPQGSFDSFTVQYKDRD--GRPRAVRVG 1419
Query: 1124 GSLRAVDIPGLKAATPYTVSIYGVIQGYRTPVLSAEASTG----ET---------PNLGE 1170
G V + GL+ Y + +YG+ +G R +SA T ET P LGE
Sbjct: 1420 GKESEVTVGGLEPGHKYKMHLYGLHEGQRVGPVSAVGVTAPQQEETPPATESPLEPRLGE 1479
Query: 1171 VVVAEVGWDALKLNWTAPEGAYEYFFIQVQEADTVEAAQNLTVPGGLRSTDLPGLKAATH 1230
+ V +V +++ L+WT PEG ++ F +Q ++ D Q + V R + L+
Sbjct: 1480 LTVTDVTPNSVGLSWTVPEGQFDSFIVQYKDKD--GQPQVVPVAADQREVTVYNLEPERK 1537
Query: 1231 YTITIRGVTQDFSTTPLSVEVLTEEVPD--------------MGNLTVTEVSWDALRLNW 1276
Y + + G+ PLSV ++T +P +G LTVT+++ D++ L+W
Sbjct: 1538 YKMNMYGLHDGQRMGPLSVVIVTAPLPPAPATEASKPPLEPRLGELTVTDITPDSVGLSW 1597
Query: 1277 TTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTVTLHGEVRGHSTR 1336
T P+G +D F +Q ++ D + + V R + IP L Y L G G
Sbjct: 1598 TVPEGEFDSFVVQYKDRDGQPQV--VPVAADQREVTIPDLEPSRKYKFLLFGIQDGKRRS 1655
Query: 1337 PLAVEVVTEDL--------PQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQVQEVNKVE 1388
P++VE T P+LG+L V++ D LRL+WT + ++ FV+Q ++ +
Sbjct: 1656 PVSVEAKTVARGDASPGAPPRLGELWVTDPTPDSLRLSWTVPEGQFDSFVVQFKD---KD 1712
Query: 1389 AAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEAST------------- 1435
Q + + G R+V + L+A YR +YG++ R L+A+ +T
Sbjct: 1713 GPQVVPVEGHERSVTVTPLDAGRKYRFLLYGLLGKKRHGPLTADGTTEARSAMDDTGTKR 1772
Query: 1436 AKEPEIG-NLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTAH 1494
+P +G L V+ +T S LSW +G F++F ++ D + + V + G+ R
Sbjct: 1773 PPKPRLGEELQVTTVTQNSVGLSWTVPEGQFDSFVVQYKDRDGQPQVVP--VEGSLREVS 1830
Query: 1495 ISGLPPSTDFIVYLSGLAPSIRTKTISATATTEAL----------------PLLENLTIS 1538
+ GL P+ + + L GL R ISA A T P L LT+
Sbjct: 1831 VPGLDPAHRYKLLLYGLHHGKRVGPISAVAITAGREETETETTAPTPPAPEPHLGELTVE 1890
Query: 1539 DINPYGFTVSWMASENAFDSFLVTVVD-SGKLLDPQEFTLSGTQRKLELRGLITGIGYEV 1597
+ + +SWM +E FDSF + D G+L Q + G + + L GL + Y V
Sbjct: 1891 EATSHTLHLSWMVTEGEFDSFEIQYTDRDGQL---QMVRIGGDRNDITLSGLESDHRYLV 1947
Query: 1598 MVSGFTQGHQTKPLRAEIVTEAE-----------------PEVDNLLVSDATPDGFRLSW 1640
+ GF+ G P+ E +T E P + L V+DATPD LSW
Sbjct: 1948 TLYGFSDGKHVGPVHVEALTVPEEEKPSEPPTATPEPPIKPRLGELTVTDATPDSLSLSW 2007
Query: 1641 TADEGVFDNFVLKIRDTKKQSEPLEITLLAPERTRDITGLREATEYEIELYGISKGRRSQ 1700
T EG FD+F+++ R+ +P + + E I+GL +Y++ LYG G+R
Sbjct: 2008 TVPEGQFDHFLVQYRN--GDGQPKAVRVPGHEEGVTISGLEPDHKYKMNLYGFHGGQRMG 2065
Query: 1701 TVSAIATTA------------MGSPK--------EVIFSDITENSATVSWRAPTAQVESF 1740
VS + TA M +P+ E+ + + +S ++SW P + +SF
Sbjct: 2066 PVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSF 2125
Query: 1741 RITYVPITGGTPSMVTVDGTKTQTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTTALD 1800
+ Y G P +V V G +++ + L PG +Y + + + PVS TA +
Sbjct: 2126 TVQYKD-RDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSAVGVTAPE 2184
Query: 1801 GPS----------GLVTANITDSEALA-RWQPAIATVDSYVISY-TGEKVPEITRTVSGN 1848
S G +T S++L+ W D +++ + G+ P+ R V G+
Sbjct: 2185 EESPDAPLAKLRLGQMTVRDITSDSLSLSWTVPEGQFDHFLVQFKNGDGQPKAVR-VPGH 2243
Query: 1849 TVEYALTDLEPATEYTLRIFAEKGPQKSSTIT-------------AKFTTDLDSP----- 1890
++ LEP +Y + ++ G Q+ ++ A +T+ +P
Sbjct: 2244 EDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAVGLTAPGKDEEMAPASTEPPTPEPPIK 2303
Query: 1891 ---RDLTATEVQSETALLTWRPPRASVTGYLLVYESVDGTVKEVIVGPDTTSYSLADLSP 1947
+LT T+ ++ L+W P +L+ Y++ DG K V +++ L P
Sbjct: 2304 PRLEELTVTDATPDSLSLSWTVPEGQFDHFLVQYKNGDGQPKATRVPGHEDRVTISGLEP 2363
Query: 1948 STHYTAKIQALNGPLRSNMIQTIFTT 1973
Y + +G R + I T
Sbjct: 2364 DNKYKMNLYGFHGGQRVGPVSAIGVT 2389
Score = 379 bits (972), Expect = e-104
Identities = 381/1596 (23%), Positives = 632/1596 (39%), Gaps = 283/1596 (17%)
Query: 628 DLVVTEVTEETVNLAWDNEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTIIQELEPGVE 687
+L VT++T ++V L+W + VV +G ++ V DQ I +LEP +
Sbjct: 1582 ELTVTDITPDSVGLSWTVPEGEFDSFVVQYKDRDGQPQV-VPVAADQREVTIPDLEPSRK 1640
Query: 688 YFIRVFAILENKKSIPVSARVATYLP------APEGLKFKSIKET---SVEVEWDPLDIA 738
Y +F I + K+ PVS T AP L + + S+ + W +
Sbjct: 1641 YKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVTDPTPDSLRLSWTVPEGQ 1700
Query: 739 FETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLH-IVKNNTRGP---- 793
F+++ + F K+ +G + E S T L G++Y L+ ++ GP
Sbjct: 1701 FDSFVVQF----KDKDGPQVVPVEGHERSVTVTPLDAGRKYRFLLYGLLGKKRHGPLTAD 1756
Query: 794 ------------GLKRVTTTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKD 841
G KR RL +++V VT + ++W P + D + Y KD
Sbjct: 1757 GTTEARSAMDDTGTKRPPKPRLG--EELQVTTVTQNSVGLSWTVPEGQFDSFVVQY--KD 1812
Query: 842 VPGDRTTIDLTEDENQYSIGNLKPDTEYEVSLIS-----RRGDMSS------NPAKETFT 890
G + + + S+ L P Y++ L R G +S+ ET T
Sbjct: 1813 RDGQPQVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVAITAGREETETET 1872
Query: 891 TGLDAPR------NLRRVSQTDNSITLEWRNGKAAIDSYRIKYAPISGGDHAEVDVPKSQ 944
T P L T +++ L W + DS+ I+Y G ++ + +
Sbjct: 1873 TAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFDSFEIQYTDRDG----QLQMVRIG 1928
Query: 945 QATTKTTLTGLRPGTEYGIGVSAVKEDKESNPATINAATELDTPK--------------- 989
TL+GL Y + + + K P + A T + K
Sbjct: 1929 GDRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSEPPTATPEPPIKP 1988
Query: 990 ---DLQVSETAETSLTLLWKTPLAKFDRYRLNYSLPTGQWVGVQLPRNTTSYVLRGLEPG 1046
+L V++ SL+L W P +FD + + Y GQ V++P + + GLEP
Sbjct: 1989 RLGELTVTDATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKAVRVPGHEEGVTISGLEPD 2048
Query: 1047 QEYNVLLTAEKGRHKSKPARVKASTE-------------QAPE------LENLTVTEVGW 1087
+Y + L G + P V T +APE L LTVT
Sbjct: 2049 HKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLLGELTVTGSSP 2108
Query: 1088 DGLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGV 1147
D L L+WT ++ F +Q ++ + + + V G V + GL+ Y + +YG+
Sbjct: 2109 DSLSLSWTVPQGRFDSFTVQYKDRD--GRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGL 2166
Query: 1148 IQGYRTPVLSAEASTG---ETPN-------LGEVVVAEVGWDALKLNWTAPEGAYEYFFI 1197
+G R +SA T E+P+ LG++ V ++ D+L L+WT PEG +++F +
Sbjct: 2167 HEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQMTVRDITSDSLSLSWTVPEGQFDHFLV 2226
Query: 1198 QVQEADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGV-----------------TQ 1240
Q + D A + VPG + GL+ Y + + G +
Sbjct: 2227 QFKNGDGQPKA--VRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAVGLTAPGK 2284
Query: 1241 DFSTTPLSVEVLTEE---VPDMGNLTVTEVSWDALRLNWTTPDGTYDQFTIQVQEADQVE 1297
D P S E T E P + LTVT+ + D+L L+WT P+G +D F +Q + D
Sbjct: 2285 DEEMAPASTEPPTPEPPIKPRLEELTVTDATPDSLSLSWTVPEGQFDHFLVQYKNGDGQP 2344
Query: 1298 EAHNLTVPGSLRSMEIPGLRAGTPYTVTLHGEVRGHSTRPLAVEVVT------------- 1344
+A VPG + I GL Y + L+G G P++ VT
Sbjct: 2345 KA--TRVPGHEDRVTISGLEPDNKYKMNLYGFHGGQRVGPVSAIGVTAAEEETPSPTEPS 2402
Query: 1345 ------EDLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQVQEVNKVEAAQNLTLPGS 1398
+ P LG+L V+ D L L+WT ++ F +Q ++ + Q + + G
Sbjct: 2403 MEAPEPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKD--RDGRPQVVRVGGE 2460
Query: 1399 LRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEASTA---------------------- 1436
V + GLE Y++ +YG+ G R +S TA
Sbjct: 2461 ESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPP 2520
Query: 1437 KEPEIGNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTAHIS 1496
+EP +G L V+ +P+S +LSW G F++FT++ D + + V + G E +
Sbjct: 2521 EEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQAV--RVGGQESKVTVR 2578
Query: 1497 GLPPSTDFIVYLSGLAPSIRTKTISATATTE-----------------ALPLLENLTISD 1539
GL P + ++L GL R +SA TE P L LT++D
Sbjct: 2579 GLEPGRKYKMHLYGLHEGRRLGPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTD 2638
Query: 1540 INPYGFTVSWMASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMV 1599
P ++SW E FD FLV + P+ + G + + + GL Y++ +
Sbjct: 2639 ATPDSLSLSWTVPEGQFDHFLVQYRNGDG--QPKAVRVPGHEDGVTISGLEPDHKYKMNL 2696
Query: 1600 SGFTQGHQTKPLR--------------AEIVTEA-----EPEVDNLLVSDATPDGFRLSW 1640
GF G + P+ E+ TEA EP + L V+ ++PD LSW
Sbjct: 2697 YGFHGGQRVGPISVIGVTAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSW 2756
Query: 1641 TADEGVFDNFVLKIRDTKKQSEPLEITLLAPERTRDITGLREATEYEIELYGISKGRR-- 1698
T +G FD+F ++ +D + P + + E + GL +Y++ LYG+ +GRR
Sbjct: 2757 TIPQGHFDSFTVQYKD--RDGRPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVG 2814
Query: 1699 -----------SQTVSAIATTAMGSPK-----EVIFSDITENSATVSWRAPTAQVESFRI 1742
++T A+ TT P E+ +D T +S ++SW P Q + F +
Sbjct: 2815 PVSTVGVTEDEAETTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLV 2874
Query: 1743 TYVPITGGTPSMVTVDGTKTQTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTTALDGP 1802
Y G P +V V G + + L P +Y +++ G + P+S TA +
Sbjct: 2875 QY-RNGDGQPKVVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEE 2933
Query: 1803 SG---------------------LVTANITDSEALARWQPAIATVDSYVISYTG-EKVPE 1840
+ VT + DS +L+ W DS+ + Y + P+
Sbjct: 2934 TPAPTEPSTEAPEPPEEPLLGELTVTGSSPDSLSLS-WTIPQGRFDSFTVQYKDRDGRPQ 2992
Query: 1841 ITRTVSGNTVEYALTDLEPATEYTLRIFAEKGPQKSSTITAKFTTDLDSPRD-------- 1892
+ R V G E + LEP +Y + ++ Q+ ++A T +P+D
Sbjct: 2993 VVR-VRGEESEVTVGGLEPGCKYKMHLYGLHEGQRVGPVSAVGVT---APKDEAETTQAV 3048
Query: 1893 ---------------LTATEVQSETALLTWRPPRASVTGYLLVYESVDGTVKEVIVGPDT 1937
LT T+ ++ L+W P +L+ Y + DG K V V
Sbjct: 3049 PTMTPEPPIKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQPKAVRVPGHE 3108
Query: 1938 TSYSLADLSPSTHYTAKIQALNGPLRSNMIQTIFTT 1973
+++ L P Y + +G R + I T
Sbjct: 3109 DGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAIGVT 3144
Score = 375 bits (964), Expect = e-103
Identities = 380/1582 (24%), Positives = 642/1582 (40%), Gaps = 266/1582 (16%)
Query: 628 DLVVTEVTEETVNLAWDNEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTIIQELEPGVE 687
+L VT + ++++L W + V +G RV G ++ + LEPG +
Sbjct: 1377 ELTVTGSSPDSLSLFWTVPQGSFDSFTVQYKDRDGR-PRAVRVGGKESEVTVGGLEPGHK 1435
Query: 688 YFIRVFAILENKKSIPVSARVAT------YLPAPEG--------LKFKSIKETSVEVEWD 733
Y + ++ + E ++ PVSA T PA E L + SV + W
Sbjct: 1436 YKMHLYGLHEGQRVGPVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWT 1495
Query: 734 PLDIAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNNTRGP 793
+ F+++ + +++ + + + + +R T Y L P ++Y+++++ + + R
Sbjct: 1496 VPEGQFDSFIVQYKDKDGQPQVVPVAADQREVTVY---NLEPERKYKMNMYGLHDGQRMG 1552
Query: 794 GLKRVTTTRLDAPS---------------QIEVKDVTDTTALITWFKPLAEIDGIELTYG 838
L V T P+ ++ V D+T + ++W P E D + Y
Sbjct: 1553 PLSVVIVTAPLPPAPATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQY- 1611
Query: 839 IKDVPGDRTTIDLTEDENQYSIGNLKPDTEYEVSLISRRGDMSSNPAK---ETFTTGLDA 895
KD G + + D+ + +I +L+P +Y+ L + +P +T G +
Sbjct: 1612 -KDRDGQPQVVPVAADQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDAS 1670
Query: 896 PRNLRRVSQ------TDNSITLEWRNGKAAIDSYRIKYAPISGGDHAEVDVPKSQQATTK 949
P R+ + T +S+ L W + DS+ +++ G V+ +
Sbjct: 1671 PGAPPRLGELWVTDPTPDSLRLSWTVPEGQFDSFVVQFKDKDGPQVVPVEGHE-----RS 1725
Query: 950 TTLTGLRPGTEYGIGVSAVKEDKESNPATINAATEL-----DT-----PK-----DLQVS 994
T+T L G +Y + + K P T + TE DT PK +LQV+
Sbjct: 1726 VTVTPLDAGRKYRFLLYGLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVT 1785
Query: 995 ETAETSLTLLWKTPLAKFDRYRLNYSLPTGQWVGVQLPRNTTSYVLRGLEPGQEYNVLL- 1053
+ S+ L W P +FD + + Y GQ V + + + GL+P Y +LL
Sbjct: 1786 TVTQNSVGLSWTVPEGQFDSFVVQYKDRDGQPQVVPVEGSLREVSVPGLDPAHRYKLLLY 1845
Query: 1054 --------------TAEKGRHKSKPARVKASTEQAPE--LENLTVTEVGWDGLRLNWTAA 1097
GR +++ A T APE L LTV E L L+W
Sbjct: 1846 GLHHGKRVGPISAVAITAGREETE-TETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVT 1904
Query: 1098 DQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVIQGYRTPVLS 1157
+ ++ F ++Q ++ + + + G + + GL++ Y V++YG G +
Sbjct: 1905 EGEFDSF--EIQYTDRDGQLQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDGKHVGPVH 1962
Query: 1158 AEASTGE-----------------TPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQ 1200
EA T P LGE+ V + D+L L+WT PEG +++F +Q +
Sbjct: 1963 VEALTVPEEEKPSEPPTATPEPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDHFLVQYR 2022
Query: 1201 EADTVEAAQNLTVPGGLRSTDLPGLKAATHY--------------TITIRGVTQDFSTTP 1246
D A + VPG + GL+ Y +++ GVT TP
Sbjct: 2023 NGDGQPKA--VRVPGHEEGVTISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETP 2080
Query: 1247 LSVEVLTE-----EVPDMGNLTVTEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHN 1301
E E E P +G LTVT S D+L L+WT P G +D FT+Q ++ D +
Sbjct: 2081 SPTEPSMEAPEPAEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQV-- 2138
Query: 1302 LTVPGSLRSMEIPGLRAGTPYTVTLHGEVRGHSTRPLAVEVVT---EDLP-------QLG 1351
+ V G + + GL G Y + L+G G P++ VT E+ P +LG
Sbjct: 2139 VRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSAVGVTAPEEESPDAPLAKLRLG 2198
Query: 1352 DLAVSEVGWDGLRLNWTAADNAYEHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAAT 1411
+ V ++ D L L+WT + ++HF++Q + N + + +PG V I GLE
Sbjct: 2199 QMTVRDITSDSLSLSWTVPEGQFDHFLVQFK--NGDGQPKAVRVPGHEDGVTISGLEPDH 2256
Query: 1412 PYRVSIYGVIRGYRTPVLSAEASTAK--------------------EPEIGNLNVSDITP 1451
Y++++YG G R +SA TA +P + L V+D TP
Sbjct: 2257 KYKMNLYGFHGGQRVGPVSAVGLTAPGKDEEMAPASTEPPTPEPPIKPRLEELTVTDATP 2316
Query: 1452 ESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTAHISGLPPSTDFIVYLSGL 1511
+S +LSW +G F+ F ++ + + + + G E ISGL P + + L G
Sbjct: 2317 DSLSLSWTVPEGQFDHFLVQYKNGDG--QPKATRVPGHEDRVTISGLEPDNKYKMNLYGF 2374
Query: 1512 APSIRTKTISATATTEA-------------------LPLLENLTISDINPYGFTVSWMAS 1552
R +SA T A PLL LT++ +P ++SW
Sbjct: 2375 HGGQRVGPVSAIGVTAAEEETPSPTEPSMEAPEPPEEPLLGELTVTGSSPDSLSLSWTVP 2434
Query: 1553 ENAFDSFLVTVVD-SGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFTQGHQTKPL 1611
+ FDSF V D G+ PQ + G + ++ + GL G Y++ + G +G + P+
Sbjct: 2435 QGRFDSFTVQYKDRDGR---PQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPV 2491
Query: 1612 RAEIVTEAEPEVD----------------------NLLVSDATPDGFRLSWTADEGVFDN 1649
VT + +VD L V+ ++PD LSWT +G FD+
Sbjct: 2492 STVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDS 2551
Query: 1650 FVLKIRDTKKQSEPLEITLLAPERTRDITGLREATEYEIELYGISKGRRSQTVSAI---- 1705
F ++ +D + P + + E + GL +Y++ LYG+ +GRR VSA+
Sbjct: 2552 FTVQYKD--RDGRPQAVRVGGQESKVTVRGLEPGRKYKMHLYGLHEGRRLGPVSAVGVTE 2609
Query: 1706 --ATTAMGSPK------------EVIFSDITENSATVSWRAPTAQVESFRITYVPITGGT 1751
A T P E+ +D T +S ++SW P Q + F + Y G
Sbjct: 2610 DEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLSLSWTVPEGQFDHFLVQY-RNGDGQ 2668
Query: 1752 PSMVTVDGTKTQTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTTALD----GPSGL-- 1805
P V V G + + L P +Y +++ G + P+S TA + P+ L
Sbjct: 2669 PKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPSPTELST 2728
Query: 1806 ---------------VTANITDSEALARWQPAIATVDSYVISYTG-EKVPEITRTVSGNT 1849
VT + DS +L+ W DS+ + Y + P++ R V G
Sbjct: 2729 EAPEPPEEPLLGELTVTGSSPDSLSLS-WTIPQGHFDSFTVQYKDRDGRPQVMR-VRGEE 2786
Query: 1850 VEYALTDLEPATEYTLRIFA-----EKGP--------QKSSTITAKFTTDLDSPR----- 1891
E + LEP +Y + ++ GP ++ T A TT + P
Sbjct: 2787 SEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTEDEAETTQAVPTTTPEPPNKPRLG 2846
Query: 1892 DLTATEVQSETALLTWRPPRASVTGYLLVYESVDGTVKEVIVGPDTTSYSLADLSPSTHY 1951
+LT T+ ++ L+W P +L+ Y + DG K V V +++ L P Y
Sbjct: 2847 ELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQPKVVRVPGHEDGVTISGLEPDHKY 2906
Query: 1952 TAKIQALNGPLRSNMIQTIFTT 1973
+ +G R I I T
Sbjct: 2907 KMNLYGFHGGQRVGPISVIGVT 2928
Score = 292 bits (748), Expect = 2e-78
Identities = 273/1138 (23%), Positives = 468/1138 (41%), Gaps = 167/1138 (14%)
Query: 984 ELDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYSLPTGQWVG----VQLPRNTTSYV 1039
E+ T + +++ ET++ W D Y + + +PT + ++P + ++Y
Sbjct: 748 EVPTIEGMRMHLLEETTVRTEWTPAPGPVDAYEIQF-IPTTEGASPPFTARVPSSASAYD 806
Query: 1040 LRGLEPGQEYNVLLTAEKGRHKSKPARVKASTEQAPELENLTVTEVGWDGLRLNWTAADQ 1099
RGL PGQEY V + A +G PA K T ++L V V L L W
Sbjct: 807 QRGLAPGQEYQVTVRALRGTSWGLPAS-KTITTMIDGPQDLRVVAVTPTTLELGWLRPQA 865
Query: 1100 AYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVIQGYRTPVLSAE 1159
+ F++ A L VP + L Y V++ + S
Sbjct: 866 EVDRFVVSYVSAGNQRV--RLEVPPEADGTLLTDLMPGVEYVVTVTAERGRAVSYPASVR 923
Query: 1160 ASTGETP-------------------------------NLGEV-VVAEVGWDALKLNWTA 1187
A+TG +P LGE+ V+ L++ WTA
Sbjct: 924 ANTGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRPQELGELRVLGRDETGRLRVVWTA 983
Query: 1188 PEGAYEYFFIQVQEADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTT-P 1246
+ YF ++++ + A + + +PG +R +P T Y +++ GV + P
Sbjct: 984 QPDTFAYFQLRMRVPEGPGAHEEV-LPGDVRQALVPPPPPGTPYELSLHGVPPGGKPSDP 1042
Query: 1247 LSVEVLTEE----------VPDMGNLTVTEVSWDALRLNWTTPDGTYDQFTIQVQEADQV 1296
+ + + ++ P +G LTVT+ + D+L L WT P+G +D F IQ ++ D
Sbjct: 1043 IIYQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPEGEFDSFVIQYKDRDGQ 1102
Query: 1297 EEAHNLTVPGSLRSMEIPGLRAGTPYTVTLHGEVRGHSTRPLAVEVVTEDLPQ------- 1349
+ + V G RS I L G Y L+G V PL E + LPQ
Sbjct: 1103 PQV--VPVEGPQRSAVITSLDPGRKYKFVLYGFVGKKRHGPLVAEA--KILPQSDPSPGT 1158
Query: 1350 ---LGDLAVSEVGWDGLRLNWTAADNAYEHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPG 1406
LG+L V++ D L L+WT + ++ F++Q ++ + Q + + G R+ +
Sbjct: 1159 PPHLGNLWVTDPTPDSLHLSWTVPEGQFDTFMVQYRD--RDGRPQVVPVEGPERSFVVSS 1216
Query: 1407 LEAATPYRVSIYGVIRGYRTPVLSAEASTAKE-------------PEIGNLNVSDITPES 1453
L+ YR +++G+ R L+A+ +TA E P +G L V+ +TP+S
Sbjct: 1217 LDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGELTVTGVTPDS 1276
Query: 1454 FNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTAHISGLPPSTDFIVYLSGLAP 1513
LSW G F++F ++ D+ + V ++G E + GL P + + L GL
Sbjct: 1277 LRLSWTVAQGPFDSFMVQYKDAQGQPQAVP--VAGDENEVTVPGLDPDRKYKMNLYGLRG 1334
Query: 1514 SIRT---KTISATATTEAL-------------------PLLENLTISDINPYGFTVSWMA 1551
R ++ TA E + PLL LT++ +P ++ W
Sbjct: 1335 RQRVGPESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELTVTGSSPDSLSLFWTV 1394
Query: 1552 SENAFDSFLVTVVD-SGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFTQGHQTKP 1610
+ +FDSF V D G+ P+ + G + ++ + GL G Y++ + G +G + P
Sbjct: 1395 PQGSFDSFTVQYKDRDGR---PRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQRVGP 1451
Query: 1611 LRAEIVTEA-------------EPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRDT 1657
+ A VT EP + L V+D TP+ LSWT EG FD+F+++ +D
Sbjct: 1452 VSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDSFIVQYKD- 1510
Query: 1658 KKQSEPLEITLLAPERTRDITGLREATEYEIELYGISKGRRSQTVSAIATTAMGSPK--- 1714
K +P + + A +R + L +Y++ +YG+ G+R +S + TA P
Sbjct: 1511 -KDGQPQVVPVAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPPAPAT 1569
Query: 1715 ------------EVIFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSMVTVDGTKT 1762
E+ +DIT +S +SW P + +SF + Y G P +V V +
Sbjct: 1570 EASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQYKD-RDGQPQVVPVAADQR 1628
Query: 1763 QTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTTALDGPSG----------LVTANITD 1812
+ + L P +Y + ++ + PVS T G + VT D
Sbjct: 1629 EVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVTDPTPD 1688
Query: 1813 SEALARWQPAIATVDSYVISYTGEKVPEITRTVSGNTVEYALTDLEPATEYTLRIFAEKG 1872
S L+ W DS+V+ + + P++ V G+ +T L+ +Y ++ G
Sbjct: 1689 SLRLS-WTVPEGQFDSFVVQFKDKDGPQVV-PVEGHERSVTVTPLDAGRKYRFLLYGLLG 1746
Query: 1873 PQKSSTITAKFTTDLDSPRDLTATE---------------VQSETALLTWRPPRASVTGY 1917
++ +TA TT+ S D T T+ V + L+W P +
Sbjct: 1747 KKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPEGQFDSF 1806
Query: 1918 LLVYESVDGTVKEVIVGPDTTSYSLADLSPSTHYTAKIQALNGPLRSNMIQTIFTTIG 1975
++ Y+ DG + V V S+ L P+ Y + L+ R I + T G
Sbjct: 1807 VVQYKDRDGQPQVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVAITAG 1864
Score = 168 bits (426), Expect = 5e-41
Identities = 200/831 (24%), Positives = 319/831 (38%), Gaps = 122/831 (14%)
Query: 1254 EEVPDMGNLTVTEVSWDALRLNWTTPDGTYDQFTIQ-VQEADQVEEAHNLTVPGSLRSME 1312
EEVP + + + + +R WT G D + IQ + + VP S + +
Sbjct: 747 EEVPTIEGMRMHLLEETTVRTEWTPAPGPVDAYEIQFIPTTEGASPPFTARVPSSASAYD 806
Query: 1313 IPGLRAGTPYTVTLHGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWDGLRLNWTAADN 1372
GL G Y VT+ +RG S A + +T + DL V V L L W
Sbjct: 807 QRGLAPGQEYQVTVRA-LRGTSWGLPASKTITTMIDGPQDLRVVAVTPTTLELGWLRPQA 865
Query: 1373 AYEHFVIQVQEVNKVEAAQNLTLP----GSLRAVDIPGLE----------AATPYRVSI- 1417
+ FV+ V+ L +P G+L +PG+E A Y S+
Sbjct: 866 EVDRFVVSY--VSAGNQRVRLEVPPEADGTLLTDLMPGVEYVVTVTAERGRAVSYPASVR 923
Query: 1418 -------YGVIRGYRTPVLSAEAST--AKEP-------EIGNLNV--SDITPESFNLSWM 1459
G++ P S ++T A+ P E+G L V D T + W
Sbjct: 924 ANTGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRPQELGELRVLGRDETGR-LRVVWT 982
Query: 1460 ATDGIFETFTIEIIDSNRLLE---TVEYNISGAERTAHISGLPPSTDFIVYLSGLAPS-- 1514
A F F + + R+ E E + G R A + PP T + + L G+ P
Sbjct: 983 AQPDTFAYFQLRM----RVPEGPGAHEEVLPGDVRQALVPPPPPGTPYELSLHGVPPGGK 1038
Query: 1515 ---------IRTKTISATATTEALPLLENLTISDINPYGFTVSWMASENAFDSFLVTVVD 1565
I K + P L LT++D + W E FDSF++ D
Sbjct: 1039 PSDPIIYQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPEGEFDSFVIQYKD 1098
Query: 1566 SGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFTQGHQTKPLRAE--IVTEAEPE- 1622
PQ + G QR + L G Y+ ++ GF + PL AE I+ +++P
Sbjct: 1099 RDG--QPQVVPVEGPQRSAVITSLDPGRKYKFVLYGFVGKKRHGPLVAEAKILPQSDPSP 1156
Query: 1623 -----VDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQSEPLEITLLAPERTRDI 1677
+ NL V+D TPD LSWT EG FD F+++ RD + P + + PER+ +
Sbjct: 1157 GTPPHLGNLWVTDPTPDSLHLSWTVPEGQFDTFMVQYRD--RDGRPQVVPVEGPERSFVV 1214
Query: 1678 TGLREATEYEIELYGISKGRRSQTVSAIATTAMGSPKE--------------VIFSDITE 1723
+ L +Y L+GI+ +R ++A TTA +E + + +T
Sbjct: 1215 SSLDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGELTVTGVTP 1274
Query: 1724 NSATVSWRAPTAQVESFRITYVPITGGTPSMVTVDGTKTQTRLVKLIPGVEYLVSIIAMK 1783
+S +SW +SF + Y G P V V G + + + L P +Y +++ ++
Sbjct: 1275 DSLRLSWTVAQGPFDSFMVQYKDAQG-QPQAVPVAGDENEVTVPGLDPDRKYKMNLYGLR 1333
Query: 1784 GFEESEPVSGSFTTA-------LDGPSGL-----------------VTANITDSEALARW 1819
G + P S TA P+ L VT + DS +L W
Sbjct: 1334 GRQRVGPESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELTVTGSSPDSLSLF-W 1392
Query: 1820 QPAIATVDSYVISYTGEKVPEITRTVSGNTVEYALTDLEPATEYTLRIFA-----EKGPQ 1874
+ DS+ + Y V G E + LEP +Y + ++ GP
Sbjct: 1393 TVPQGSFDSFTVQYKDRDGRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQRVGPV 1452
Query: 1875 KSSTITAKFTTDLD-------SPR--DLTATEVQSETALLTWRPPRASVTGYLLVYESVD 1925
+ +TA + PR +LT T+V + L+W P +++ Y+ D
Sbjct: 1453 SAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDSFIVQYKDKD 1512
Query: 1926 GTVKEVIVGPDTTSYSLADLSPSTHYTAKIQALNGPLRSNMIQTIFTTIGL 1976
G + V V D ++ +L P Y + L+ R + + T L
Sbjct: 1513 GQPQVVPVAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPL 1563
Score = 36.2 bits (82), Expect = 0.36
Identities = 29/87 (33%), Positives = 39/87 (44%), Gaps = 5/87 (5%)
Query: 626 PKDLVVTEVTEETVNLAW-DNEMRVTEYLV-VYTPTHEGGLEMQFRVPGDQTSTIIQELE 683
P+DL EVT T L W + +R YL+ +TP GG + +PG TS + L
Sbjct: 3934 PRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTP---GGQNQEILLPGGITSHQLLGLF 3990
Query: 684 PGVEYFIRVFAILENKKSIPVSARVAT 710
P Y R+ A+ PVS T
Sbjct: 3991 PSTSYNARLQAMWGQSLLPPVSTSFTT 4017
>gi|157384973 tenascin R [Homo sapiens]
Length = 1358
Score = 645 bits (1665), Expect = 0.0
Identities = 337/935 (36%), Positives = 529/935 (56%), Gaps = 19/935 (2%)
Query: 485 CVCDDGYTGEDCRDRQCPRDCSNRGLCVDGQCVCEDGFTGPDCAELSCPNDCHGQGRCVN 544
C+C++G+ G++C + CP CS+RG+CVDGQC+C+ ++G DC+EL CP DC +G CV+
Sbjct: 188 CICNEGWFGKNCSEPYCPLGCSSRGVCVDGQCICDSEYSGDDCSELRCPTDCSSRGLCVD 247
Query: 545 GQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLDCGQHSCPSDCNNLGQC 604
G+CVC E + G+DC+E RCP DC G+GRC +G C+C EG+ G DCGQ C + C+ GQC
Sbjct: 248 GECVCEEPYTGEDCRELRCPGDCSGKGRCANGTCLCEEGYVGEDCGQRQCLNACSGRGQC 307
Query: 605 VSGRCICNEGYSGEDCSEVSPPKDLVVTEVTEETVNLAWDNEMRVTEYLVVYTPTHEGGL 664
G C+C EGY G DCS V+PP+DL V +++ ++ L WD M VTEY++ Y PT GGL
Sbjct: 308 EEGLCVCEEGYQGPDCSAVAPPEDLRVAGISDRSIELEWDGPMAVTEYVISYQPTALGGL 367
Query: 665 EMQFRVPGDQTSTIIQELEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFKSIK 724
++Q RVPGD + I ELEPG+ Y I V+A++ N S+P++A+VAT+L P+GL+FK+I
Sbjct: 368 QLQQRVPGDWSGVTITELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTIT 427
Query: 725 ETSVEVEWDPLDIAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLH 784
ET+VEV+W+P +F+ WEI F + K +EG + + TS+ QTGL PG+EY +++
Sbjct: 428 ETTVEVQWEPFSFSFDGWEISF--IPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVV 485
Query: 785 IVKNNTRGPGLKRVTTTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPG 844
+K R P +T +D P+QI V+DV+DT A + W P A++D I L YG+ G
Sbjct: 486 ALKEQARSPPTSASVSTVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEG 545
Query: 845 DRTTIDLTEDENQYSIGNLKPDTEYEVSLISRRGDMSSNPAKETFTTGLDAPRNLRRVSQ 904
RTT L +QYS+ L+P + YEVS+ + RG S+ A FTT +DAP+NLR S+
Sbjct: 546 GRTTFRLQPPLSQYSVQALRPGSRYEVSVSAVRGTNESDSATTQFTTEIDAPKNLRVGSR 605
Query: 905 TDNSITLEWRNGKAAIDSYRIKYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIG 964
T S+ LEW N +A + Y++ Y+ ++G + EV VP+ TT+ TLT L PGTEYG+G
Sbjct: 606 TATSLDLEWDNSEAEVQEYKVVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVG 665
Query: 965 VSAVKEDKESNPATINAATELDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYSLPTG 1024
+SAV ++S PAT+NA TELD+P+DL V+ ++ETS++L+W D YR+ ++ +G
Sbjct: 666 ISAVMNSQQSVPATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPSSG 725
Query: 1025 QWVGVQLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTEQAPELENLTVTE 1084
V +P++ TSY L LEPG EY + +TAE+GR +S + V A T P + +L +
Sbjct: 726 IASEVTVPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRP-ISHLHFSH 784
Query: 1085 VGWDGLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSI 1144
V + + W+ + I+ ++ E +++ + R + GL+ AT Y V++
Sbjct: 785 VTSSSVNITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNL 844
Query: 1145 YGVIQGYRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEADT 1204
V + + +TG P ++ ++ V D++ ++W+ P +++Y+ + +
Sbjct: 845 VAVHGTVTSEPIVGSITTGIDPP-KDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQ- 902
Query: 1205 VEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLTEEVPDMGNLTV 1264
V + VP + + L AT Y I++ V + + V T + + +L
Sbjct: 903 VGRLDSSVVPNTVTEFTITRLNPATEYEISLNSVRGREESERICTLVHT-AMDNPVDLIA 961
Query: 1265 TEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTV 1324
T ++ L W P G + + I + E + V G + L T YT
Sbjct: 962 TNITPTEALLQWKAPVGEVENYVIVLTHFAVAGE--TILVDGVSEEFRLVDLLPSTHYTA 1019
Query: 1325 TLHGEVRGHSTRPLAVEVVTEDLPQLGD----LAVSEVGWDGLRLNWTAADNAYEHFVIQ 1380
T++ + PL ++ + L D L SEV ++W E++V+
Sbjct: 1020 TMYA-----TNGPLTSGTISTNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENYVLT 1074
Query: 1381 VQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRV 1415
+ + + + L + + + GL T Y V
Sbjct: 1075 YKSTD--GSRKELIVDAEDTWIRLEGLLENTDYTV 1107
Score = 598 bits (1542), Expect = e-170
Identities = 354/1062 (33%), Positives = 550/1062 (51%), Gaps = 31/1062 (2%)
Query: 1149 QGYRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEADTVEAA 1208
+GY+ P SA A + + VA + +++L W P EY I Q
Sbjct: 316 EGYQGPDCSAVAPPED------LRVAGISDRSIELEWDGPMAVTEYV-ISYQPTALGGLQ 368
Query: 1209 QNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLTEEVPDMG------NL 1262
VPG + L+ Y I++ V + + P++ +V T G
Sbjct: 369 LQQRVPGDWSGVTITELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTITE 428
Query: 1263 TVTEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTPY 1322
T EV W+ ++ DG F + E + + VP + S GL+ G Y
Sbjct: 429 TTVEVQWEPFSFSF---DGWEISFIPKNNEGGVIAQ-----VPSDVTSFNQTGLKPGEEY 480
Query: 1323 TVTLHGEVRGHSTRPLAVEVVTE-DLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQV 1381
V + + P + V T D P + V +V + W + +++
Sbjct: 481 IVNVVALKEQARSPPTSASVSTVIDGPT--QILVRDVSDTVAFVEWIPPRAKVDFILLKY 538
Query: 1382 QEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEASTAKEPEI 1441
V L L + L + Y VS+ +RG + T +
Sbjct: 539 GLVGGEGGRTTFRLQPPLSQYSVQALRPGSRYEVSV-SAVRGTNESDSATTQFTTEIDAP 597
Query: 1442 GNLNVSDITPESFNLSWMATDGIFETFTI--EIIDSNRLLETVEYNISGAERTAHISGLP 1499
NL V T S +L W ++ + + + + + E + G A ++ L
Sbjct: 598 KNLRVGSRTATSLDLEWDNSEAEVQEYKVVYSTLAGEQYHEVLVPRGIGPTTRATLTDLV 657
Query: 1500 PSTDFIVYLSGLAPSIRTKTISATATTEALPLLENLTISDINPYGFTVSWMASENAFDSF 1559
P T++ V +S + S ++ + A TE L +L ++ + ++ W + D +
Sbjct: 658 PGTEYGVGISAVMNSQQSVPATMNARTE-LDSPRDLMVTASSETSISLIWTKASGPIDHY 716
Query: 1560 LVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFTQGHQTKPLRAEIVTEA 1619
+T S + E T+ + L L G Y + V+ Q+ + T
Sbjct: 717 RITFTPSSGIAS--EVTVPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGF 774
Query: 1620 EPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQSEPLEITLLAPERTRDITG 1679
P + +L S T ++W+ D +L ++ E +E++L A +R + G
Sbjct: 775 RP-ISHLHFSHVTSSSVNITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMG 833
Query: 1680 LREATEYEIELYGISKGRRSQTVSAIATTAMGSPKEVIFSDITENSATVSWRAPTAQVES 1739
L+ ATEY + L + S+ + TT + PK++ S++T++S VSW P A +
Sbjct: 834 LQPATEYIVNLVAVHGTVTSEPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDY 893
Query: 1740 FRITYVPITGGTPSMVTVDGTKTQTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTTAL 1799
+R++Y P G V T T+ + +L P EY +S+ +++G EESE + TA+
Sbjct: 894 YRVSYRPTQVGRLDSSVVPNTVTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAM 953
Query: 1800 DGPSGLVTANITDSEALARWQPAIATVDSYVISYTGEKVPEITRTVSGNTVEYALTDLEP 1859
D P L+ NIT +EAL +W+ + V++YVI T V T V G + E+ L DL P
Sbjct: 954 DNPVDLIATNITPTEALLQWKAPVGEVENYVIVLTHFAVAGETILVDGVSEEFRLVDLLP 1013
Query: 1860 ATEYTLRIFAEKGPQKSSTITAKFTTDLDSPRDLTATEVQSETALLTWRPPRASVTGYLL 1919
+T YT ++A GP S TI+ F+T LD P +LTA+EV ++AL++W+PPRA + Y+L
Sbjct: 1014 STHYTATMYATNGPLTSGTISTNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENYVL 1073
Query: 1920 VYESVDGTVKEVIVGPDTTSYSLADLSPSTHYTAKIQALNGPLRSNMIQTIFTTIGLLYP 1979
Y+S DG+ KE+IV + T L L +T YT +QA S++ T FTT G ++P
Sbjct: 1074 TYKSTDGSRKELIVDAEDTWIRLEGLLENTDYTVLLQAAQDTTWSSITSTAFTTGGRVFP 1133
Query: 1980 FPKDCSQAMLNGDTTSGLYTIYLNGDKAEALEVFCDMTSDGGGWIVFLRRKNGRENFYQN 2039
P+DC+Q ++NGDT SG+Y I+LNG+ ++ L+V+CDMT+DGGGWIVF RR+NG+ +F++
Sbjct: 1134 HPQDCAQHLMNGDTLSGVYPIFLNGELSQKLQVYCDMTTDGGGWIVFQRRQNGQTDFFRK 1193
Query: 2040 WKAYAAGFGDRREEFWLGLDNLNKITAQGQYELRVDLRDHGETAFAVYDKFSVGDAKTRY 2099
W Y GFG+ +EFWLGLDN+++IT+QG+YELRVD+RD E AFA YD+FSV D++ Y
Sbjct: 1194 WADYRVGFGNVEDEFWLGLDNIHRITSQGRYELRVDMRDGQEAAFASYDRFSVEDSRNLY 1253
Query: 2100 KLKVEGYSGTAGDSMAYHNGRSFSTFDKDTDSAITNCALSYKGAFWYRNCHRVNLMGRYG 2159
KL++ Y+GTAGDS++YH GR FST D+D D A+TNCA+SYKGA+WY+NCHR NL G+YG
Sbjct: 1254 KLRIGSYNGTAGDSLSYHQGRPFSTEDRDNDVAVTNCAMSYKGAWWYKNCHRTNLNGKYG 1313
Query: 2160 DNNHSQGVNWFHWKGHEHSIQFAEMKLRPSNFRNLEGRRKRA 2201
++ HSQG+NW+HWKGHE SI F EMK+RP N R + GR++++
Sbjct: 1314 ESRHSQGINWYHWKGHEFSIPFVEMKMRPYNHRLMAGRKRQS 1355
Score = 414 bits (1064), Expect = e-115
Identities = 287/957 (29%), Positives = 441/957 (46%), Gaps = 57/957 (5%)
Query: 392 CECDDGFTGADCGELKCPNGCSGHGRCVNGQCVCDEGYTGEDCSQLRCPNDCHSRGRCVE 451
C C++G+ G +C E CP GCS G CV+GQC+CD Y+G+DCS+LRCP DC SRG CV+
Sbjct: 188 CICNEGWFGKNCSEPYCPLGCSSRGVCVDGQCICDSEYSGDDCSELRCPTDCSSRGLCVD 247
Query: 452 GKCVCEQGFKGYDCSDMSCPNDCHQHGRCVNGMCVCDDGYTGEDCRDRQCPRDCSNRGLC 511
G+CVCE+ + G DC ++ CP DC GRC NG C+C++GY GEDC RQC CS RG C
Sbjct: 248 GECVCEEPYTGEDCRELRCPGDCSGKGRCANGTCLCEEGYVGEDCGQRQCLNACSGRGQC 307
Query: 512 VDGQCVCEDGFTGPDCAELSCPNDCHGQG-------------RCVNGQCVCHE-GFMGKD 557
+G CVCE+G+ GPDC+ ++ P D G V + ++ +G
Sbjct: 308 EEGLCVCEEGYQGPDCSAVAPPEDLRVAGISDRSIELEWDGPMAVTEYVISYQPTALGGL 367
Query: 558 CKEQRCPSDCHGQGRCVDGQCICHEGFTGLDCGQHSCPSDCNNLGQCVSGRCICNEGYSG 617
+QR P D G T L+ P N+ I + +
Sbjct: 368 QLQQRVPGDWSG------------VTITELE------PGLTYNISVYAVISNILSLPITA 409
Query: 618 EDCSEVSPPKDLVVTEVTEETVNLAWDN-EMRVTEYLVVYTP-THEGGLEMQFRVPGDQT 675
+ + +S P+ L +TE TV + W+ + + + P +EGG+ Q VP D T
Sbjct: 410 KVATHLSTPQGLQFKTITETTVEVQWEPFSFSFDGWEISFIPKNNEGGVIAQ--VPSDVT 467
Query: 676 STIIQELEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPL 735
S L+PG EY + V A+ E +S P SA V+T + P + + + +T VEW P
Sbjct: 468 SFNQTGLKPGEEYIVNVVALKEQARSPPTSASVSTVIDGPTQILVRDVSDTVAFVEWIP- 526
Query: 736 DIAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNNTRGPGL 795
A + ++ + + G T L+ P + Y L PG YE+S+ V+
Sbjct: 527 PRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQYSVQALRPGSRYEVSVSAVRGTNESDSA 586
Query: 796 KRVTTTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTE-- 853
TT +DAP + V T T+ + W AE+ ++ Y + G++ L
Sbjct: 587 TTQFTTEIDAPKNLRVGSRTATSLDLEWDNSEAEVQEYKVVY--STLAGEQYHEVLVPRG 644
Query: 854 --DENQYSIGNLKPDTEYEVSLISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSITL 911
+ ++ +L P TEY V + + S PA T LD+PR+L + ++ SI+L
Sbjct: 645 IGPTTRATLTDLVPGTEYGVGISAVMNSQQSVPATMNARTELDSPRDLMVTASSETSISL 704
Query: 912 EWRNGKAAIDSYRIKYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKED 971
W ID YRI + P S G +EV VPK + T TLT L PG EY I V+A +
Sbjct: 705 IWTKASGPIDHYRITFTP-SSGIASEVTVPKDR---TSYTLTDLEPGAEYIISVTAERGR 760
Query: 972 KESNPATINAATELDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYSL--PTGQWVGV 1029
++S +T++A T L S +S+ + W P DR LNYS + + V
Sbjct: 761 QQSLESTVDAFTGFRPISHLHFSHVTSSSVNITWSDPSPPADRLILNYSPRDEEEEMMEV 820
Query: 1030 QLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTEQAPELENLTVTEVGWDG 1089
L VL GL+P EY V L A G S+P +T P +++T++ V D
Sbjct: 821 SLDATKRHAVLMGLQPATEYIVNLVAVHGTVTSEPIVGSITTGIDPP-KDITISNVTKDS 879
Query: 1090 LRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVIQ 1149
+ ++W+ +++++ + + +V + VP ++ I L AT Y +S+ V
Sbjct: 880 VMVSWSPPVASFDYYRVSYR-PTQVGRLDSSVVPNTVTEFTITRLNPATEYEISLNSVRG 938
Query: 1150 GYRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEADTVEAAQ 1209
+ + T N +++ + L W AP G E + I + A +
Sbjct: 939 REESERICTLVHTA-MDNPVDLIATNITPTEALLQWKAPVGEVENYVIVL--THFAVAGE 995
Query: 1210 NLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLTEEVPDMGNLTVTEVSW 1269
+ V G L L +THYT T+ ++ +S T P NLT +EV+
Sbjct: 996 TILVDGVSEEFRLVDLLPSTHYTATMYATNGPLTSGTISTNFSTLLDPP-ANLTASEVTR 1054
Query: 1270 DALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTVTL 1326
+ ++W P + + + + D + L V + + GL T YTV L
Sbjct: 1055 QSALISWQPPRAEIENYVLTYKSTDGSRK--ELIVDAEDTWIRLEGLLENTDYTVLL 1109
Score = 314 bits (805), Expect = 5e-85
Identities = 145/283 (51%), Positives = 187/283 (66%), Gaps = 6/283 (2%)
Query: 38 NATLPEENQPVVFNHVYNIKLPVGSQCSVDLESASGEKDLAPPSEPSESFQEHTVDGENQ 97
N + QPVVFNHVYNI +P+ + CS LE AS E++++ E + T D E+Q
Sbjct: 53 NYNTSSKEQPVVFNHVYNINVPLDNLCSSGLE-ASAEQEVSAEDETLAEYMGQTSDHESQ 111
Query: 98 IVFTHRINIPRRACGCAAAPDV-KELLSRLEELENLVSSLREQCTAGAGCCLQPA-TGRL 155
+ FTHRIN P++AC CA++ V +ELLSR+E LE VS LR+QC A CC + A TG+L
Sbjct: 112 VTFTHRINFPKKACPCASSAQVLQELLSRIEMLEREVSVLRDQCNAN--CCQESAATGQL 169
Query: 156 DTRPFCSGRGNFSTEGCGCVCEPGWKGPNCSEPECPGNCHLRGRCIDGQCICDDGFTGED 215
D P CSG GNFS E CGC+C GW G NCSEP CP C RG C+DGQCICD ++G+D
Sbjct: 170 DYIPHCSGHGNFSFESCGCICNEGWFGKNCSEPYCPLGCSSRGVCVDGQCICDSEYSGDD 229
Query: 216 CSQLACPSDCNDQGKCVNGVCICFEGYAGADCSREICPVPCSEEHGTCVDGLCVCHDGFA 275
CS+L CP+DC+ +G CV+G C+C E Y G DC CP CS + G C +G C+C +G+
Sbjct: 230 CSELRCPTDCSSRGLCVDGECVCEEPYTGEDCRELRCPGDCSGK-GRCANGTCLCEEGYV 288
Query: 276 GDDCNKPLCLNNCYNRGRCVENECVCDEGFTGEDCSELICPND 318
G+DC + CLN C RG+C E CVC+EG+ G DCS + P D
Sbjct: 289 GEDCGQRQCLNACSGRGQCEEGLCVCEEGYQGPDCSAVAPPED 331
Score = 207 bits (526), Expect = 1e-52
Identities = 81/149 (54%), Positives = 105/149 (70%)
Query: 330 CYCEEGFTGEDCGKPTCPHACHTQGRCEEGQCVCDEGFAGVDCSEKRCPADCHNRGRCVD 389
C C EG+ G++C +P CP C ++G C +GQC+CD ++G DCSE RCP DC +RG CVD
Sbjct: 188 CICNEGWFGKNCSEPYCPLGCSSRGVCVDGQCICDSEYSGDDCSELRCPTDCSSRGLCVD 247
Query: 390 GRCECDDGFTGADCGELKCPNGCSGHGRCVNGQCVCDEGYTGEDCSQLRCPNDCHSRGRC 449
G C C++ +TG DC EL+CP CSG GRC NG C+C+EGY GEDC Q +C N C RG+C
Sbjct: 248 GECVCEEPYTGEDCRELRCPGDCSGKGRCANGTCLCEEGYVGEDCGQRQCLNACSGRGQC 307
Query: 450 VEGKCVCEQGFKGYDCSDMSCPNDCHQHG 478
EG CVCE+G++G DCS ++ P D G
Sbjct: 308 EEGLCVCEEGYQGPDCSAVAPPEDLRVAG 336
Score = 188 bits (477), Expect = 6e-47
Identities = 71/149 (47%), Positives = 99/149 (66%)
Query: 299 CVCDEGFTGEDCSELICPNDCFDRGRCINGTCYCEEGFTGEDCGKPTCPHACHTQGRCEE 358
C+C+EG+ G++CSE CP C RG C++G C C+ ++G+DC + CP C ++G C +
Sbjct: 188 CICNEGWFGKNCSEPYCPLGCSSRGVCVDGQCICDSEYSGDDCSELRCPTDCSSRGLCVD 247
Query: 359 GQCVCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECDDGFTGADCGELKCPNGCSGHGRC 418
G+CVC+E + G DC E RCP DC +GRC +G C C++G+ G DCG+ +C N CSG G+C
Sbjct: 248 GECVCEEPYTGEDCRELRCPGDCSGKGRCANGTCLCEEGYVGEDCGQRQCLNACSGRGQC 307
Query: 419 VNGQCVCDEGYTGEDCSQLRCPNDCHSRG 447
G CVC+EGY G DCS + P D G
Sbjct: 308 EEGLCVCEEGYQGPDCSAVAPPEDLRVAG 336
Score = 177 bits (448), Expect = 1e-43
Identities = 65/142 (45%), Positives = 96/142 (67%)
Query: 268 CVCHDGFAGDDCNKPLCLNNCYNRGRCVENECVCDEGFTGEDCSELICPNDCFDRGRCIN 327
C+C++G+ G +C++P C C +RG CV+ +C+CD ++G+DCSEL CP DC RG C++
Sbjct: 188 CICNEGWFGKNCSEPYCPLGCSSRGVCVDGQCICDSEYSGDDCSELRCPTDCSSRGLCVD 247
Query: 328 GTCYCEEGFTGEDCGKPTCPHACHTQGRCEEGQCVCDEGFAGVDCSEKRCPADCHNRGRC 387
G C CEE +TGEDC + CP C +GRC G C+C+EG+ G DC +++C C RG+C
Sbjct: 248 GECVCEEPYTGEDCRELRCPGDCSGKGRCANGTCLCEEGYVGEDCGQRQCLNACSGRGQC 307
Query: 388 VDGRCECDDGFTGADCGELKCP 409
+G C C++G+ G DC + P
Sbjct: 308 EEGLCVCEEGYQGPDCSAVAPP 329
Score = 152 bits (385), Expect = 3e-36
Identities = 120/438 (27%), Positives = 191/438 (43%), Gaps = 13/438 (2%)
Query: 621 SEVSPPKDLVVTEVTEETVNLAWDNEMR-VTEYLVVYTPTHEGGLEMQFRVPGDQTSTII 679
+E+ P+DL+VT +E +++L W + Y + +TP+ G+ + VP D+TS +
Sbjct: 684 TELDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPS--SGIASEVTVPKDRTSYTL 741
Query: 680 QELEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFKSIKETSVEVEW-DPLDIA 738
+LEPG EY I V A ++S+ + T L F + +SV + W DP A
Sbjct: 742 TDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVNITWSDPSPPA 801
Query: 739 FETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNNTRGPGLKRV 798
I+ + E+E + SL + GL P EY ++L V +
Sbjct: 802 DRL--ILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTVTSEPIVGS 859
Query: 799 TTTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQY 858
TT +D P I + +VT + +++W P+A D ++Y V G + + ++
Sbjct: 860 ITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQV-GRLDSSVVPNTVTEF 918
Query: 859 SIGNLKPDTEYEVSLISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSITLEWRNGKA 918
+I L P TEYE+SL S RG S T +D P +L + T L+W+
Sbjct: 919 TITRLNPATEYEISLNSVRGREESERICTLVHTAMDNPVDLIATNITPTEALLQWKAPVG 978
Query: 919 AIDSYRIKYAPIS-GGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKEDKESNPA 977
+++Y I + G+ VD + + L L P T Y + A S
Sbjct: 979 EVENYVIVLTHFAVAGETILVD-----GVSEEFRLVDLLPSTHYTATMYATNGPLTSGTI 1033
Query: 978 TINAATELDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYSLPTGQWVGVQLPRNTTS 1037
+ N +T LD P +L SE S + W+ P A+ + Y L Y G + + T
Sbjct: 1034 STNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENYVLTYKSTDGSRKELIVDAEDTW 1093
Query: 1038 YVLRGLEPGQEYNVLLTA 1055
L GL +Y VLL A
Sbjct: 1094 IRLEGLLENTDYTVLLQA 1111
Score = 95.9 bits (237), Expect = 4e-19
Identities = 71/284 (25%), Positives = 123/284 (43%), Gaps = 7/284 (2%)
Query: 610 ICNEGYSGEDCSEVSPPKDLVVTEVTEETVNLAWDNEMRVTEYL-VVYTPTHEGGLEMQF 668
+ +E G + + PPKD+ ++ VT+++V ++W + +Y V Y PT G L+
Sbjct: 851 VTSEPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQVGRLDSSV 910
Query: 669 RVPGDQTSTIIQELEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFKSIKETSV 728
VP T I L P EY I + ++ ++S + V T + P L +I T
Sbjct: 911 -VPNTVTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMDNPVDLIATNITPTEA 969
Query: 729 EVEWDPLDIAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKN 788
++W E + I+ + E + + +R L P Y +++
Sbjct: 970 LLQWKAPVGEVENYVIVLTHFAVAGETILVDGVSE---EFRLVDLLPSTHYTATMYATNG 1026
Query: 789 NTRGPGLKRVTTTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTT 848
+ +T LD P+ + +VT +ALI+W P AEI+ LTY K G R
Sbjct: 1027 PLTSGTISTNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENYVLTY--KSTDGSRKE 1084
Query: 849 IDLTEDENQYSIGNLKPDTEYEVSLISRRGDMSSNPAKETFTTG 892
+ + ++ + L +T+Y V L + + S+ FTTG
Sbjct: 1085 LIVDAEDTWIRLEGLLENTDYTVLLQAAQDTTWSSITSTAFTTG 1128
Score = 72.0 bits (175), Expect = 6e-12
Identities = 37/100 (37%), Positives = 52/100 (52%), Gaps = 8/100 (8%)
Query: 135 SLREQCTAGAGCCLQPATGRLDTRPF-----CSGRGNFSTEGCGCVCEPGWKGPNCSEPE 189
S R C G C +P TG D R CSG+G + C +CE G+ G +C + +
Sbjct: 240 SSRGLCVDGECVCEEPYTGE-DCRELRCPGDCSGKGRCANGTC--LCEEGYVGEDCGQRQ 296
Query: 190 CPGNCHLRGRCIDGQCICDDGFTGEDCSQLACPSDCNDQG 229
C C RG+C +G C+C++G+ G DCS +A P D G
Sbjct: 297 CLNACSGRGQCEEGLCVCEEGYQGPDCSAVAPPEDLRVAG 336
>gi|62988324 tenascin N [Homo sapiens]
Length = 1299
Score = 544 bits (1401), Expect = e-154
Identities = 332/1039 (31%), Positives = 529/1039 (50%), Gaps = 41/1039 (3%)
Query: 1179 DALKLNWTAPEGAYEYFFIQVQEADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGV 1238
D+L ++W P +++ + + + + VP S ++ GL T Y +T+R V
Sbjct: 276 DSLLVSWE-PSSQVDHYLLSYYPLGKELSGKQIQVPKEQHSYEILGLLPGTKYIVTLRNV 334
Query: 1239 TQDFSTTPLSVEVLTEEVPDMGNLTVTEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEE 1298
+ S++P + + T ++ +G VT+ + ++L + W P D + ++ E
Sbjct: 335 KNEVSSSPQHL-LATTDLAVLGTAWVTDETENSLDVEWENPSTEVDYYKLRYGPMTGQEV 393
Query: 1299 AHNLTVPGSL---RSMEIPGLRAGTPYTVT---LHGEVRGHSTRPLAVEVVTE-DLPQLG 1351
A +TVP S +I GL GT Y +T + GE+ G +P+ + TE D P
Sbjct: 394 AE-VTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEG---KPILLNGRTEIDSPT-- 447
Query: 1352 DLAVSEVGWDGLRLNWTAADNAYEHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAAT 1411
++ V D ++W + +V++ + + + + + + GL+
Sbjct: 448 NVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSADG--DTKEMAVHKDESSTVLTGLKPGE 505
Query: 1412 PYRVSIYGVIRGYRTPVLSAEASTAKEPEI---GNLNVSDITPESFNLSWMATDGIFETF 1468
Y+V ++ RG + S +A T EI NL +T + +SW + +
Sbjct: 506 AYKVYVWAE-RGNQG---SKKADTNALTEIDSPANLVTDRVTENTATISWDPVQATIDKY 561
Query: 1469 TIEIIDSNRLLETVEYNISGAERTAHISGLPPSTDFIVYLSGLAPSIRTKTISATATTEA 1528
+ ++ ET E + + + ++GL P ++ V++ +K A T+
Sbjct: 562 VVRYTSADDQ-ETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESKKADTNAPTD- 619
Query: 1529 LPLLENLTISDINPYGFTVSWMASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELRG 1588
+ +NL + TVSW + A D ++V +G + +E + Q L G
Sbjct: 620 IDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYTSAGG--ETREVPVGKEQSSTVLTG 677
Query: 1589 LITGIGYEVMVSGFTQGHQTKPLRAEIVTEAEPEVD---NLLVSDATPDGFRLSWTADEG 1645
L G+ Y MV + Q + +A+ T+A+ ++D NL+ T + +SW
Sbjct: 678 LRPGMEY--MVHVWAQKGDQESKKAD--TKAQTDIDSPQNLVTDRVTENMATVSWDPVRA 733
Query: 1646 VFDNFVLKIRDTKKQSEPLEITLLAPERTRDITGLREATEYEIELYGISKGRRSQTVSAI 1705
D +V++ K E E+ + + + +TGLR EY + ++ + S+
Sbjct: 734 TIDRYVVRYTSAK-DGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQESKKADTK 792
Query: 1706 ATTAMGSPKEVIFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSMVTVDGTKTQTR 1765
A T + SP+ ++ +TEN+ATVSW A ++ + + Y G T V V ++ T
Sbjct: 793 AQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYTSANGETRE-VPVGKEQSSTV 851
Query: 1766 LVKLIPGVEYLVSIIAMKGFEESEPVSGSFTTALDGPSGLVTANITDSEALARWQPAIAT 1825
L L PG+EY V + A KG +ES+ T +DGP LVT +T++ A W P AT
Sbjct: 852 LTGLRPGMEYTVHVWAQKGNQESKKADTKAQTEIDGPKNLVTDWVTENMATVSWDPVQAT 911
Query: 1826 VDSYVISYTGEKVPEITRTVSGNTVEYALTDLEPATEYTLRIFAEKGPQKSSTITAKFTT 1885
+D Y++ YT V LT L P EY + ++A+KG Q+S K T
Sbjct: 912 IDKYMVRYTSADGETREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGAQESKKADTKAQT 971
Query: 1886 DLDSPRDLTATEVQSETALLTWRPPRASVTGYLLVYESVDGTVKEVIVGPDTTSYSLADL 1945
+LD PR+L + V +LTW PP A + GY+L Y+ DGTVKE+ +G + ++L L
Sbjct: 972 ELDPPRNLRPSAVTQSGGILTWTPPSAQIHGYILTYQFPDGTVKEMQLGREDQRFALQGL 1031
Query: 1946 SPSTHYTAKIQALNGPLRSNMIQTIFTTIGLLYPFPKDCSQAMLNGDTTSGLYTIYLNGD 2005
Y + A G RS + T +T+G +P P DCSQ N + SGLYTIYL+GD
Sbjct: 1032 EQGATYPVSLVAFKGGRRSRNVSTTLSTVGARFPHPSDCSQVQQNSNAASGLYTIYLHGD 1091
Query: 2006 KAEALEVFCDMTSDGGGWIVFLRRKNGRENFYQNWKAYAAGFGDRREEFWLGLDNLNKIT 2065
+ L+V+CDM +DGGGWIVF RR G+ +F++ W++Y GFGD +EFWLGLD L+ +T
Sbjct: 1092 ASRPLQVYCDMETDGGGWIVFQRRNTGQLDFFKRWRSYVEGFGDPMKEFWLGLDKLHNLT 1151
Query: 2066 --AQGQYELRVDLRDHGETAFAVYDKFSVGDAKTRYKLKVEGYSGTAGDSMAYHNGRSFS 2123
+YE+RVDL+ E+A+A+YD F V +K RYKL V Y GTAGD++ YHNG F+
Sbjct: 1152 TGTPARYEVRVDLQTANESAYAIYDFFQVASSKERYKLTVGKYRGTAGDALTYHNGWKFT 1211
Query: 2124 TFDKDTDSAITNCALSYKGAFWYRNCHRVNLMGRYGDNNHSQGVNWFHWKGHEHSIQFAE 2183
TFD+D D A++NCAL++ G +WY+NCH N GRYG+ HS+GVNW WKGHE SI + E
Sbjct: 1212 TFDRDNDIALSNCALTHHGGWWYKNCHLANPNGRYGETKHSEGVNWEPWKGHEFSIPYVE 1271
Query: 2184 MKLRPSNFRN--LEGRRKR 2200
+K+RP + + GR+KR
Sbjct: 1272 LKIRPHGYSREPVLGRKKR 1290
Score = 398 bits (1023), Expect = e-110
Identities = 273/955 (28%), Positives = 436/955 (45%), Gaps = 32/955 (3%)
Query: 494 EDCRDRQC-------PRDCSNRGL--CVDGQCVCEDGFTGPDCAELSCPNDCHGQGRCVN 544
E C ++C R CS G C CE+G GP C L+CP C G GRCV+
Sbjct: 124 EQCSAQRCCQGVTDLSRHCSGHGTFSLETCSCHCEEGREGPACERLACPGACSGHGRCVD 183
Query: 545 GQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLDCGQHSCPSDCNNLGQC 604
G+C+CHE ++G DC CP +C G G CV G C CHE F DC + CP DC+ G C
Sbjct: 184 GRCLCHEPYVGADCGYPACPENCSGHGECVRGVCQCHEDFMSEDCSEKRCPGDCSGHGFC 243
Query: 605 VSGRCICNEGYSGEDCSEVSPPKDLVVTEVTEETVNLAWDNEMRVTEYLVVYTPTHEGGL 664
+G C C EG++G DC++V P+ L + + TE+++ ++W+ +V YL+ Y P +
Sbjct: 244 DTGECYCEEGFTGLDCAQVVTPQGLQLLKNTEDSLLVSWEPSSQVDHYLLSYYPLGKELS 303
Query: 665 EMQFRVPGDQTSTIIQELEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFKSIK 724
Q +VP +Q S I L PG +Y + + + S P T L
Sbjct: 304 GKQIQVPKEQHSYEILGLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDET 363
Query: 725 ETSVEVEWDPLDIAFETWEIIFRNMNKEDEGEIT-KSLRRPETSYRQTGLAPGQEYEISL 783
E S++VEW+ + +++ + M ++ E+T P++ Y TGL PG EY+I++
Sbjct: 364 ENSLDVEWENPSTEVDYYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITV 423
Query: 784 HIVKNNTRGPGLKRVTTTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVP 843
++ G + T +D+P+ + VT+ TA ++W A ID + Y D
Sbjct: 424 VPMRGELEGKPILLNGRTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSAD-- 481
Query: 844 GDRTTIDLTEDENQYSIGNLKPDTEYEVSLISRRGDMSSNPAKETFTTGLDAPRNLRRVS 903
GD + + +DE+ + LKP Y+V + + RG+ S A T +D+P NL
Sbjct: 482 GDTKEMAVHKDESSTVLTGLKPGEAYKVYVWAERGNQGSKKADTNALTEIDSPANLVTDR 541
Query: 904 QTDNSITLEWRNGKAAIDSYRIKYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGI 963
T+N+ T+ W +A ID Y ++Y + EV V K Q + T LTGLRPG EY +
Sbjct: 542 VTENTATISWDPVQATIDKYVVRYTSADDQETREVLVGKEQ---SSTVLTGLRPGVEYTV 598
Query: 964 GVSAVKEDKESNPATINAATELDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYSLPT 1023
V A K D+ES A NA T++D+PK+L E T+ W A D+Y + Y+
Sbjct: 599 HVWAQKGDRESKKADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYTSAG 658
Query: 1024 GQWVGVQLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTEQAPELENLTVT 1083
G+ V + + +S VL GL PG EY V + A+KG +SK A KA T+ +NL
Sbjct: 659 GETREVPVGKEQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQTD-IDSPQNLVTD 717
Query: 1084 EVGWDGLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVS 1143
V + ++W + ++++ A E R + V + + GL+ YTV
Sbjct: 718 RVTENMATVSWDPVRATIDRYVVRYTSAKDGE-TREVPVGKEQSSTVLTGLRPGVEYTVH 776
Query: 1144 IYGVIQGYRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEAD 1203
++ + +A T + + +V V + ++W + + + + A+
Sbjct: 777 VWAQKGAQESKKADTKAQT-DIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYTSAN 835
Query: 1204 TVEAAQNLTVPGGLR--STDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLTEEVPDMGN 1261
+ VP G ST L GL+ YT+ + + + + T E+ N
Sbjct: 836 ----GETREVPVGKEQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQT-EIDGPKN 890
Query: 1262 LTVTEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTP 1321
L V+ + ++W T D++ ++ AD E + V S + GLR G
Sbjct: 891 LVTDWVTENMATVSWDPVQATIDKYMVRYTSAD--GETREVPVGKEHSSTVLTGLRPGME 948
Query: 1322 YTVTLHGEVRGHSTRPLAVEVVTE-DLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQ 1380
Y V + + ++ + TE D P+ +L S V G L WT +++
Sbjct: 949 YMVHVWAQKGAQESKKADTKAQTELDPPR--NLRPSAVTQSGGILTWTPPSAQIHGYILT 1006
Query: 1381 VQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEAST 1435
Q + + + L + + GLE Y VS+ G R+ +S ST
Sbjct: 1007 YQFPD--GTVKEMQLGREDQRFALQGLEQGATYPVSLVAFKGGRRSRNVSTTLST 1059
Score = 336 bits (862), Expect = 1e-91
Identities = 265/959 (27%), Positives = 413/959 (43%), Gaps = 69/959 (7%)
Query: 432 EDCSQLRCPNDCHSRGRCVEG---------KCVCEQGFKGYDCSDMSCPNDCHQHGRCVN 482
E CS RC R G C CE+G +G C ++CP C HGRCV+
Sbjct: 124 EQCSAQRCCQGVTDLSRHCSGHGTFSLETCSCHCEEGREGPACERLACPGACSGHGRCVD 183
Query: 483 GMCVCDDGYTGEDCRDRQCPRDCSNRGLCVDGQCVCEDGFTGPDCAELSCPNDCHGQGRC 542
G C+C + Y G DC CP +CS G CV G C C + F DC+E CP DC G G C
Sbjct: 184 GRCLCHEPYVGADCGYPACPENCSGHGECVRGVCQCHEDFMSEDCSEKRCPGDCSGHGFC 243
Query: 543 VNGQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLDCGQHSCPSDCNNLG 602
G+C C EGF G DC + P D + E + +D H S LG
Sbjct: 244 DTGECYCEEGFTGLDCAQVVTPQGLQLLKNTEDSLLVSWEPSSQVD---HYLLS-YYPLG 299
Query: 603 QCVSGRCI--CNEGYSGEDC----------------SEV-SPPKDLV------------V 631
+ +SG+ I E +S E +EV S P+ L+ V
Sbjct: 300 KELSGKQIQVPKEQHSYEILGLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWV 359
Query: 632 TEVTEETVNLAWDN-EMRVTEYLVVYTP-THEGGLEMQFRVPGDQTSTI-IQELEPGVEY 688
T+ TE ++++ W+N V Y + Y P T + E+ D S I L PG EY
Sbjct: 360 TDETENSLDVEWENPSTEVDYYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEY 419
Query: 689 FIRVFAILENKKSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPLDIAFETWEIIFRN 748
I V + + P+ T + +P + + E + V WDP+ + + + + +
Sbjct: 420 KITVVPMRGELEGKPILLNGRTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTS 479
Query: 749 MNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNNTRGPGLKRVTTTRLDAPSQ 808
+ + + ++ + E+S TGL PG+ Y++ + + N T +D+P+
Sbjct: 480 ADGDTK---EMAVHKDESSTVLTGLKPGEAYKVYVWAERGNQGSKKADTNALTEIDSPAN 536
Query: 809 IEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQYSIGNLKPDTE 868
+ VT+ TA I+W A ID + Y D R + + ++++ + L+P E
Sbjct: 537 LVTDRVTENTATISWDPVQATIDKYVVRYTSADDQETREVL-VGKEQSSTVLTGLRPGVE 595
Query: 869 YEVSLISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSITLEWRNGKAAIDSYRIKYA 928
Y V + +++GD S A T +D+P+NL T+N T+ W +AAID Y ++Y
Sbjct: 596 YTVHVWAQKGDRESKKADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYT 655
Query: 929 PISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKEDKESNPATINAATELDTP 988
+GG+ EV V K Q + T LTGLRPG EY + V A K D+ES A A T++D+P
Sbjct: 656 S-AGGETREVPVGKEQ---SSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSP 711
Query: 989 KDLQVSETAETSLTLLWKTPLAKFDRYRLNY-SLPTGQWVGVQLPRNTTSYVLRGLEPGQ 1047
++L E T+ W A DRY + Y S G+ V + + +S VL GL PG
Sbjct: 712 QNLVTDRVTENMATVSWDPVRATIDRYVVRYTSAKDGETREVPVGKEQSSTVLTGLRPGV 771
Query: 1048 EYNVLLTAEKGRHKSKPARVKASTEQAPELENLTVTEVGWDGLRLNWTAADQAYEHFIIQ 1107
EY V + A+KG +SK A KA T+ +NL V + ++W + +++
Sbjct: 772 EYTVHVWAQKGAQESKKADTKAQTD-IDSPQNLVTDWVTENTATVSWDPVQATIDRYVVH 830
Query: 1108 VQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVIQGYRTPVLSAEASTGETPN 1167
AN R + V + + GL+ YTV ++ + +A T E
Sbjct: 831 YTSAN--GETREVPVGKEQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQT-EIDG 887
Query: 1168 LGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEADTVEAAQNLTVPGGLR--STDLPGL 1225
+V V + ++W + + + ++ AD + VP G ST L GL
Sbjct: 888 PKNLVTDWVTENMATVSWDPVQATIDKYMVRYTSAD----GETREVPVGKEHSSTVLTGL 943
Query: 1226 KAATHYTITIRGVTQDFSTTPLSVEVLTEEVPDMGNLTVTEVSWDALRLNWTTPDGTYDQ 1285
+ Y + + + + TE P NL + V+ L WT P
Sbjct: 944 RPGMEYMVHVWAQKGAQESKKADTKAQTELDPPR-NLRPSAVTQSGGILTWTPPSAQIHG 1002
Query: 1286 FTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTVTLHGEVRGHSTRPLAVEVVT 1344
+ + Q D + + + + GL G Y V+L G +R ++ + T
Sbjct: 1003 YILTYQFPDGT--VKEMQLGREDQRFALQGLEQGATYPVSLVAFKGGRRSRNVSTTLST 1059
Score = 179 bits (454), Expect = 3e-44
Identities = 91/236 (38%), Positives = 122/236 (51%), Gaps = 12/236 (5%)
Query: 44 ENQPVVFNHVYNIKLPVGSQCSVDLESASGEKDLAPPSEPSESFQEHTVDGENQIVFTHR 103
+ Q V +H Y I +P + VD + D A E+ +E I+F H
Sbjct: 36 KEQQVTVSHTYKIDVPKSALVQVDADPQPLSDDGASLLALGEAREEQN------IIFRHN 89
Query: 104 INIPRRACGCAAAPDVKELLSRLEELENLVSSLREQCTAGAGCCLQPATGRLDTRPFCSG 163
I + C A V++LL+R+++LE + ++EQC+A CC G D CSG
Sbjct: 90 IRLQTPQKDCELAGSVQDLLARVKKLEEEMVEMKEQCSAQR-CC----QGVTDLSRHCSG 144
Query: 164 RGNFSTEGCGCVCEPGWKGPNCSEPECPGNCHLRGRCIDGQCICDDGFTGEDCSQLACPS 223
G FS E C C CE G +GP C CPG C GRC+DG+C+C + + G DC ACP
Sbjct: 145 HGTFSLETCSCHCEEGREGPACERLACPGACSGHGRCVDGRCLCHEPYVGADCGYPACPE 204
Query: 224 DCNDQGKCVNGVCICFEGYAGADCSREICPVPCSEEHGTCVDGLCVCHDGFAGDDC 279
+C+ G+CV GVC C E + DCS + CP CS HG C G C C +GF G DC
Sbjct: 205 NCSGHGECVRGVCQCHEDFMSEDCSEKRCPGDCS-GHGFCDTGECYCEEGFTGLDC 259
Score = 146 bits (368), Expect = 3e-34
Identities = 60/140 (42%), Positives = 80/140 (57%), Gaps = 9/140 (6%)
Query: 403 CGELKCPNG-------CSGHGR--CVNGQCVCDEGYTGEDCSQLRCPNDCHSRGRCVEGK 453
C +C G CSGHG C C+EG G C +L CP C GRCV+G+
Sbjct: 126 CSAQRCCQGVTDLSRHCSGHGTFSLETCSCHCEEGREGPACERLACPGACSGHGRCVDGR 185
Query: 454 CVCEQGFKGYDCSDMSCPNDCHQHGRCVNGMCVCDDGYTGEDCRDRQCPRDCSNRGLCVD 513
C+C + + G DC +CP +C HG CV G+C C + + EDC +++CP DCS G C
Sbjct: 186 CLCHEPYVGADCGYPACPENCSGHGECVRGVCQCHEDFMSEDCSEKRCPGDCSGHGFCDT 245
Query: 514 GQCVCEDGFTGPDCAELSCP 533
G+C CE+GFTG DCA++ P
Sbjct: 246 GECYCEEGFTGLDCAQVVTP 265
Score = 143 bits (361), Expect = 2e-33
Identities = 63/140 (45%), Positives = 75/140 (53%), Gaps = 5/140 (3%)
Query: 332 CEEGFTGEDCGKPTCPHACHTQGRCEEGQCVCDEGFAGVDCSEKRCPADCHNRGRCVDGR 391
C +G T D + H + C C C+EG G C CP C GRCVDGR
Sbjct: 131 CCQGVT--DLSRHCSGHGTFSLETCS---CHCEEGREGPACERLACPGACSGHGRCVDGR 185
Query: 392 CECDDGFTGADCGELKCPNGCSGHGRCVNGQCVCDEGYTGEDCSQLRCPNDCHSRGRCVE 451
C C + + GADCG CP CSGHG CV G C C E + EDCS+ RCP DC G C
Sbjct: 186 CLCHEPYVGADCGYPACPENCSGHGECVRGVCQCHEDFMSEDCSEKRCPGDCSGHGFCDT 245
Query: 452 GKCVCEQGFKGYDCSDMSCP 471
G+C CE+GF G DC+ + P
Sbjct: 246 GECYCEEGFTGLDCAQVVTP 265
Score = 140 bits (353), Expect = 1e-32
Identities = 60/142 (42%), Positives = 77/142 (54%), Gaps = 9/142 (6%)
Query: 308 EDCSELICPNDCFDRGRCING---------TCYCEEGFTGEDCGKPTCPHACHTQGRCEE 358
E CS C D R +G +C+CEEG G C + CP AC GRC +
Sbjct: 124 EQCSAQRCCQGVTDLSRHCSGHGTFSLETCSCHCEEGREGPACERLACPGACSGHGRCVD 183
Query: 359 GQCVCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECDDGFTGADCGELKCPNGCSGHGRC 418
G+C+C E + G DC CP +C G CV G C+C + F DC E +CP CSGHG C
Sbjct: 184 GRCLCHEPYVGADCGYPACPENCSGHGECVRGVCQCHEDFMSEDCSEKRCPGDCSGHGFC 243
Query: 419 VNGQCVCDEGYTGEDCSQLRCP 440
G+C C+EG+TG DC+Q+ P
Sbjct: 244 DTGECYCEEGFTGLDCAQVVTP 265
Score = 139 bits (350), Expect = 3e-32
Identities = 59/141 (41%), Positives = 73/141 (51%), Gaps = 9/141 (6%)
Query: 372 CSEKRCPADCHNRGRCVDGR---------CECDDGFTGADCGELKCPNGCSGHGRCVNGQ 422
CS +RC + R G C C++G G C L CP CSGHGRCV+G+
Sbjct: 126 CSAQRCCQGVTDLSRHCSGHGTFSLETCSCHCEEGREGPACERLACPGACSGHGRCVDGR 185
Query: 423 CVCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCEQGFKGYDCSDMSCPNDCHQHGRCVN 482
C+C E Y G DC CP +C G CV G C C + F DCS+ CP DC HG C
Sbjct: 186 CLCHEPYVGADCGYPACPENCSGHGECVRGVCQCHEDFMSEDCSEKRCPGDCSGHGFCDT 245
Query: 483 GMCVCDDGYTGEDCRDRQCPR 503
G C C++G+TG DC P+
Sbjct: 246 GECYCEEGFTGLDCAQVVTPQ 266
Score = 139 bits (349), Expect = 4e-32
Identities = 55/113 (48%), Positives = 63/113 (55%)
Query: 299 CVCDEGFTGEDCSELICPNDCFDRGRCINGTCYCEEGFTGEDCGKPTCPHACHTQGRCEE 358
C C+EG G C L CP C GRC++G C C E + G DCG P CP C G C
Sbjct: 155 CHCEEGREGPACERLACPGACSGHGRCVDGRCLCHEPYVGADCGYPACPENCSGHGECVR 214
Query: 359 GQCVCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECDDGFTGADCGELKCPNG 411
G C C E F DCSEKRCP DC G C G C C++GFTG DC ++ P G
Sbjct: 215 GVCQCHEDFMSEDCSEKRCPGDCSGHGFCDTGECYCEEGFTGLDCAQVVTPQG 267
Score = 137 bits (345), Expect = 1e-31
Identities = 69/167 (41%), Positives = 77/167 (46%), Gaps = 10/167 (5%)
Query: 214 EDCSQLACPSDCNDQGKCVNG---------VCICFEGYAGADCSREICPVPCSEEHGTCV 264
E CS C D + +G C C EG G C R CP CS HG CV
Sbjct: 124 EQCSAQRCCQGVTDLSRHCSGHGTFSLETCSCHCEEGREGPACERLACPGACSG-HGRCV 182
Query: 265 DGLCVCHDGFAGDDCNKPLCLNNCYNRGRCVENECVCDEGFTGEDCSELICPNDCFDRGR 324
DG C+CH+ + G DC P C NC G CV C C E F EDCSE CP DC G
Sbjct: 183 DGRCLCHEPYVGADCGYPACPENCSGHGECVRGVCQCHEDFMSEDCSEKRCPGDCSGHGF 242
Query: 325 CINGTCYCEEGFTGEDCGKPTCPHACHTQGRCEEGQCVCDEGFAGVD 371
C G CYCEEGFTG DC + P E+ V E + VD
Sbjct: 243 CDTGECYCEEGFTGLDCAQVVTPQGLQLLKNTEDSLLVSWEPSSQVD 289
Score = 120 bits (301), Expect = 1e-26
Identities = 49/121 (40%), Positives = 63/121 (52%), Gaps = 2/121 (1%)
Query: 260 HGTCVDGLCVCH--DGFAGDDCNKPLCLNNCYNRGRCVENECVCDEGFTGEDCSELICPN 317
HGT C CH +G G C + C C GRCV+ C+C E + G DC CP
Sbjct: 145 HGTFSLETCSCHCEEGREGPACERLACPGACSGHGRCVDGRCLCHEPYVGADCGYPACPE 204
Query: 318 DCFDRGRCINGTCYCEEGFTGEDCGKPTCPHACHTQGRCEEGQCVCDEGFAGVDCSEKRC 377
+C G C+ G C C E F EDC + CP C G C+ G+C C+EGF G+DC++
Sbjct: 205 NCSGHGECVRGVCQCHEDFMSEDCSEKRCPGDCSGHGFCDTGECYCEEGFTGLDCAQVVT 264
Query: 378 P 378
P
Sbjct: 265 P 265
>gi|20665034 tenascin XB isoform 2 [Homo sapiens]
Length = 673
Score = 521 bits (1341), Expect = e-147
Identities = 275/671 (40%), Positives = 387/671 (57%), Gaps = 23/671 (3%)
Query: 1547 VSWMASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFTQGH 1606
+SW ++ FDSF+V D+ PQ + G Q K+ + GL Y ++ G +G
Sbjct: 3 LSWSVAQGPFDSFVVQYEDTNG--QPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGK 60
Query: 1607 QTKPLRAEIVT----------EAEPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRD 1656
+ PL AE T E+ P + L V+D T RL+W A G FD+F+L+
Sbjct: 61 RLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGV 120
Query: 1657 TKKQS-EP-----LEITLLAP--ERTRDITGLREATEYEIELYGISKGRRSQTVSAIATT 1708
+ EP L+ L+ P + + LR T Y + LYG+ ++ ++ A T
Sbjct: 121 PSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTART 180
Query: 1709 ---AMGSPKEVIFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSMVTVDGTKTQTR 1765
+ SP+++ FS+I E SA V+W P ++ +SF+++Y GG P V VDG +
Sbjct: 181 LSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQK 240
Query: 1766 LVKLIPGVEYLVSIIAMKGFEESEPVSGSFTTALDGPSGLVTANITDSEALARWQPAIAT 1825
L LIPG Y V++++++GFEESEP++G TT DGP+ L N+T+ A+ W+P
Sbjct: 241 LQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNP 300
Query: 1826 VDSYVISYTGEKVPEITRTVSGNTVEYALTDLEPATEYTLRIFAEKGPQKSSTITAKFTT 1885
VD+Y + T P + G+ V+Y L DL T YT + +GP +S + FTT
Sbjct: 301 VDTYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTT 360
Query: 1886 DLDSPRDLTATEVQSETALLTWRPPRASVTGYLLVYESVDGTVKEVIVGPDTTSYSLADL 1945
L++PRDL A EV TALLTW P GYLL + + G +E+++ TS+ L L
Sbjct: 361 GLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLGL 420
Query: 1946 SPSTHYTAKIQALNGPLRSNMIQTIFTTIGLLYPFPKDCSQAMLNGDTTSGLYTIYLNGD 2005
PST Y A++QA+ G + T FTT GL PFP+DC + M NG S TI+LNG+
Sbjct: 421 FPSTSYNARLQAMWGQSLLPPVSTSFTTGGLRIPFPRDCGEEMQNGAGASRTSTIFLNGN 480
Query: 2006 KAEALEVFCDMTSDGGGWIVFLRRKNGRENFYQNWKAYAAGFGDRREEFWLGLDNLNKIT 2065
+ L VFCDM +DGGGW+VF RR +G+ +F+++W+ YA GFG+ EFWLG + L+ +T
Sbjct: 481 RERPLNVFCDMETDGGGWLVFQRRMDGQTDFWRDWEDYAHGFGNISGEFWLGNEALHSLT 540
Query: 2066 AQGQYELRVDLRDHGETAFAVYDKFSVGDAKTRYKLKVEGYSGTAGDSMAYHNGRSFSTF 2125
G Y +RVDLR E FA YD F V A Y+L +EGY GTAGDSM+YH+G FS
Sbjct: 541 QAGDYSMRVDLRAGDEAVFAQYDSFHVDSAAEYYRLHLEGYHGTAGDSMSYHSGSVFSAR 600
Query: 2126 DKDTDSAITNCALSYKGAFWYRNCHRVNLMGRYGDNNHSQGVNWFHWKGHEHSIQFAEMK 2185
D+D +S + +CA+SY+GA+WYRNCH NL G YG QGV+W+HWKG E S+ F EMK
Sbjct: 601 DRDPNSLLISCAVSYRGAWWYRNCHYANLNGLYGSTVDHQGVSWYHWKGFEFSVPFTEMK 660
Query: 2186 LRPSNFRNLEG 2196
LRP NFR+ G
Sbjct: 661 LRPRNFRSPAG 671
Score = 150 bits (378), Expect = 2e-35
Identities = 126/459 (27%), Positives = 206/459 (44%), Gaps = 35/459 (7%)
Query: 1363 LRLNWTAADNAYEHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIR 1422
+RL+W+ A ++ FV+Q ++ N Q L + G + I GLE +TPYR +YG+
Sbjct: 1 MRLSWSVAQGPFDSFVVQYEDTNG--QPQALLVDGDQSKILISGLEPSTPYRFLLYGLHE 58
Query: 1423 GYRTPVLSAEASTA----------KEPEIGNLNVSDITPESFNLSWMATDGIFETFTIEI 1472
G R LSAE +T P + L+V+D+T S L+W A G F++F +
Sbjct: 59 GKRLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRF 118
Query: 1473 -IDSNRLLE-------TVEYNISGAERTAHISGLPPSTDFIVYLSGLAPSIRTKTISATA 1524
+ S LE E + G +A + L T + + L GL + +I TA
Sbjct: 119 GVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTA 178
Query: 1525 TTEALPLLE---NLTISDINPYGFTVSWMASENAFDSFLVT--VVDSGKLLDPQEFTLSG 1579
T + P+LE +L S+I V+WM + DSF V+ + D G +PQ + G
Sbjct: 179 RTLS-PVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGG---EPQSVQVDG 234
Query: 1580 TQRKLELRGLITGIGYEVMVSGFTQGHQTKPLRAEIVTEAEPEVDNLLVSDATPDGFR-L 1638
R +L+GLI G YEV V +++PL + T P+ L + +GF L
Sbjct: 235 QARTQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTT--VPDGPTQLRALNLTEGFAVL 292
Query: 1639 SWTADEGVFDNFVLKIRDTKKQSEPLEITLLAPERTRDITGLREATEYEIELYGISKGRR 1698
W + D + +++ T + PL+ + L T Y + G+
Sbjct: 293 HWKPPQNPVDTYDVQV--TAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNL 350
Query: 1699 SQTVSAIATTAMGSPKEVIFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSMVTVD 1758
+ S TT + +P+++ ++T +A ++W P + + +++ GG + +
Sbjct: 351 TSPASITFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSF-HTPGGQNQEILLP 409
Query: 1759 GTKTQTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTT 1797
G T +L+ L P Y + AM G PVS SFTT
Sbjct: 410 GGITSHQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTT 448
Score = 137 bits (345), Expect = 1e-31
Identities = 112/446 (25%), Positives = 188/446 (42%), Gaps = 38/446 (8%)
Query: 652 YLVVYTPTHEGGLEMQFRVPGDQTSTIIQELEPGVEYFIRVFAILENKKSIPVSARVATY 711
++V Y T+ G V GDQ+ +I LEP Y ++ + E K+ P+SA T
Sbjct: 15 FVVQYEDTN--GQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGKRLGPLSAEGTTG 72
Query: 712 LPAPEG------------LKFKSIKETSVEVEWDPLDIAFETWEIIF-----RNMNKEDE 754
L AP G L + +S+ + W+ AF+++ + F +
Sbjct: 73 L-APAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTLEPHPR 131
Query: 755 GEITKSLRRPETSYRQT--GLAPGQEYEISLHIVKNNTRGP-------GLKRVTTTRLDA 805
+ + L P T + L G Y ++L+ RGP G R + L++
Sbjct: 132 PLLQRELMVPGTRHSAVLRDLRSGTLYSLTLY----GLRGPHKADSIQGTARTLSPVLES 187
Query: 806 PSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQYSIGNLKP 865
P ++ ++ +T+A + W P + D +++Y + D G+ ++ + + L P
Sbjct: 188 PRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLAD-GGEPQSVQVDGQARTQKLQGLIP 246
Query: 866 DTEYEVSLISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSITLEWRNGKAAIDSYRI 925
YEV+++S RG S P TT D P LR ++ T+ L W+ + +D+Y +
Sbjct: 247 GARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNPVDTYDV 306
Query: 926 KYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKEDKESNPATINAATEL 985
+ G + + P S L L T Y V ++ ++PA+I T L
Sbjct: 307 QVTA-PGAPPLQAETPGS---AVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTTGL 362
Query: 986 DTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYSLPTGQWVGVQLPRNTTSYVLRGLEP 1045
+ P+DL+ E + L W P + Y L++ P GQ + LP TS+ L GL P
Sbjct: 363 EAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLGLFP 422
Query: 1046 GQEYNVLLTAEKGRHKSKPARVKAST 1071
YN L A G+ P +T
Sbjct: 423 STSYNARLQAMWGQSLLPPVSTSFTT 448
Score = 124 bits (311), Expect = 1e-27
Identities = 126/482 (26%), Positives = 206/482 (42%), Gaps = 73/482 (15%)
Query: 1090 LRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVIQ 1149
+RL+W+ A ++ F++Q ++ N A L V G + I GL+ +TPY +YG+ +
Sbjct: 1 MRLSWSVAQGPFDSFVVQYEDTNGQPQA--LLVDGDQSKILISGLEPSTPYRFLLYGLHE 58
Query: 1150 GYRTPVLSAEASTG----------ETPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQ- 1198
G R LSAE +TG P L ++ V +V +L+LNW AP GA++ F ++
Sbjct: 59 GKRLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRF 118
Query: 1199 -VQEADTVE------AAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPL--SV 1249
V T+E + L VPG S L L++ T Y++T+ G+ + +
Sbjct: 119 GVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTA 178
Query: 1250 EVLTEEVPDMGNLTVTEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLR 1309
L+ + +L +E+ + ++NW P D F + Q AD E ++ V G R
Sbjct: 179 RTLSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADG-GEPQSVQVDGQAR 237
Query: 1310 SMEIPGLRAGTPYTVTLHGEVRG-HSTRPLA--VEVVTEDLPQLGDLAVSEVGWDGLRLN 1366
+ ++ GL G Y VT+ VRG + PL + V + QL L ++E L+
Sbjct: 238 TQKLQGLIPGARYEVTV-VSVRGFEESEPLTGFLTTVPDGPTQLRALNLTE---GFAVLH 293
Query: 1367 WTAADNAYEHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIY-------- 1418
W N + + +QV T PG+ P L+A TP Y
Sbjct: 294 WKPPQNPVDTYDVQV------------TAPGA------PPLQAETPGSAVDYPLHDLVLH 335
Query: 1419 ----GVIRGYRTPVLSAEAS---TAKEPEIGNLNVSDITPESFNLSW----MATDGIFET 1467
+RG R P L++ AS T +L ++TP + L+W + G +
Sbjct: 336 TNYTATVRGLRGPNLTSPASITFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLS 395
Query: 1468 FTIEIIDSNRLLETVEYNISGAERTAHISGLPPSTDFIVYLSGLAPSIRTKTISATATTE 1527
F + +L + G + + GL PST + L + +S + TT
Sbjct: 396 FHTPGGQNQEIL------LPGGITSHQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTTG 449
Query: 1528 AL 1529
L
Sbjct: 450 GL 451
Score = 109 bits (272), Expect = 3e-23
Identities = 115/461 (24%), Positives = 187/461 (40%), Gaps = 39/461 (8%)
Query: 1001 LTLLWKTPLAKFDRYRLNYSLPTGQWVGVQLPRNTTSYVLRGLEPGQEYNVLLTAEKGRH 1060
+ L W FD + + Y GQ + + + + ++ GLEP Y LL G H
Sbjct: 1 MRLSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLY---GLH 57
Query: 1061 KSK---PARVKAST----------EQAPELENLTVTEVGWDGLRLNWTAADQAYEHFIIQ 1107
+ K P + +T E P L L+VT+V LRLNW A A++ F+++
Sbjct: 58 EGKRLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLR 117
Query: 1108 --VQEANKVE------AARNLTVPGSLRAVDIPGLKAATPYTVSIYGVIQGYRTPVLSAE 1159
V + +E R L VPG+ + + L++ T Y++++YG+ ++ +
Sbjct: 118 FGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGT 177
Query: 1160 AST----GETPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEADTVEAAQNLTVPG 1215
A T E+P ++ +E+ + K+NW P + F + Q AD E Q++ V G
Sbjct: 178 ARTLSPVLESPR--DLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGE-PQSVQVDG 234
Query: 1216 GLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLTEEVPD-MGNLTVTEVSWDALRL 1274
R+ L GL Y +T+ V + PL+ + T VPD L ++ L
Sbjct: 235 QARTQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTT--VPDGPTQLRALNLTEGFAVL 292
Query: 1275 NWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTVTLHGEVRGHS 1334
+W P D + +QV PGS + L T YT T+ G +RG +
Sbjct: 293 HWKPPQNPVDTYDVQVTAPG--APPLQAETPGSAVDYPLHDLVLHTNYTATVRG-LRGPN 349
Query: 1335 TRPLAVEVVTEDLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQVQEVNKVEAAQNLT 1394
A T L DL EV L WT +++ Q +
Sbjct: 350 LTSPASITFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQN--QEIL 407
Query: 1395 LPGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEAST 1435
LPG + + + GL +T Y + + P +S +T
Sbjct: 408 LPGGITSHQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTT 448
Score = 75.1 bits (183), Expect = 7e-13
Identities = 68/280 (24%), Positives = 111/280 (39%), Gaps = 31/280 (11%)
Query: 626 PKDLVVTEVTEETVNLAWDNEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTIIQELEPG 685
P+DL +E+ E + + W + V +GG +V G + +Q L PG
Sbjct: 188 PRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQKLQGLIPG 247
Query: 686 VEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPLDIAFETWEII 745
Y + V ++ ++S P++ + T P L+ ++ E + W P +T+++
Sbjct: 248 ARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNPVDTYDV- 306
Query: 746 FRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNNT---------RGPGLK 796
++T P + PG + LH + +T RGP L
Sbjct: 307 ----------QVTAPGAPPLQAE-----TPGSAVDYPLHDLVLHTNYTATVRGLRGPNLT 351
Query: 797 RVT----TTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLT 852
TT L+AP +E K+VT TAL+TW +P G L++ G I L
Sbjct: 352 SPASITFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPG--GQNQEILLP 409
Query: 853 EDENQYSIGNLKPDTEYEVSLISRRGDMSSNPAKETFTTG 892
+ + L P T Y L + G P +FTTG
Sbjct: 410 GGITSHQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTTG 449
>gi|47132557 fibronectin 1 isoform 1 preproprotein [Homo sapiens]
Length = 2477
Score = 380 bits (977), Expect = e-105
Identities = 314/1291 (24%), Positives = 542/1291 (41%), Gaps = 51/1291 (3%)
Query: 626 PKDLVVTEVTEETVNLAWDN-EMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTIIQELEP 684
P D V +V + ++ + W + +T Y +VY+P+ EG + +P S + +L+P
Sbjct: 814 PPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGS-STELNLPETANSVTLSDLQP 872
Query: 685 GVEYFIRVFAILENKKSIPVSARVATY-------LPAPEGLKFKSIKETSVEVEWDPLDI 737
GV+Y I ++A+ EN++S PV + T +P+P L+F + + V + W P +
Sbjct: 873 GVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES 932
Query: 738 AFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNNTRGPGLKR 797
A + + +N E + R T TGL+PG Y + V + L
Sbjct: 933 AVTGYRVDVIPVNLPGEHGQRLPISR-NTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTA 991
Query: 798 VTTTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQ 857
TT+LDAP+ ++ + TD+T L+ W P A+I G LT G+ G ++ ++
Sbjct: 992 QQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTR-RGQPRQYNVGPSVSK 1050
Query: 858 YSIGNLKPDTEYEVSLISRRGDMSSNPAKETFTT---GLDAPRNLRRVSQTDNSITLEWR 914
Y + NL+P +EY VSL++ +G+ S A FTT G P V++T +I + W
Sbjct: 1051 YPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTET--TIVITWT 1108
Query: 915 NGKAAIDSYRIKYAPISGGDHAEVDVPKSQQATTKT-TLTGLRPGTEYGIGVSAVKEDKE 973
A +++ P GG+ P+ + + + ++GL PG EY + +++ +E
Sbjct: 1109 --PAPRIGFKLGVRPSQGGE-----APREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQE 1161
Query: 974 SNPATIN-AATELDTPKDLQVSETAETS-LTLLW-KTPLAKFDRYRLNYSLPTGQWVGVQ 1030
+ +N T L P +L + +T LT+ W ++ YR+ + PT G
Sbjct: 1162 RDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRIT-TTPTNGQQGNS 1220
Query: 1031 LPR----NTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTEQAPELENLTVTEVG 1086
L + +S L PG EYNV + K +S P E P+L +L+ ++
Sbjct: 1221 LEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPE-VPQLTDLSFVDIT 1279
Query: 1087 WDGLRLNWTAADQA-YEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIY 1145
+ L WT + + + I V A + V S+ + GL+ Y +S+
Sbjct: 1280 DSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVI 1339
Query: 1146 GVIQGYRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWTAPEGA-YEYFFIQVQEADT 1204
+I G + + T P ++ +G D +++ W P F ++
Sbjct: 1340 TLINGGESAPTTLTQQTAVPPPT-DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKN 1398
Query: 1205 VEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLTEEVPDMGNLTV 1264
E L++ + L L T Y +++ V + +TPL T G +
Sbjct: 1399 EEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTG-IDF 1457
Query: 1265 TEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTV 1324
++++ ++ ++W P T + I+ VP S S+ + L GT Y V
Sbjct: 1458 SDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVV 1517
Query: 1325 TLHGEVRGHSTRPLAV--EVVTEDLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQVQ 1382
++ + G PL + + D+P+ DL V L ++W A ++ I
Sbjct: 1518 SIVA-LNGREESPLLIGQQSTVSDVPR--DLEVVAATPTSLLISWDAPAVTVRYYRITYG 1574
Query: 1383 EVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEASTAKEPEI- 1441
E Q T+PGS I GL+ Y +++Y V +P S S EI
Sbjct: 1575 ETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1634
Query: 1442 --GNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTAHISGLP 1499
+ V+D+ S ++ W+ + + + N T + I GL
Sbjct: 1635 KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1694
Query: 1500 PSTDFIVYLSGLAPSIRTKTISATATTEALPLLENLTISDINPYGFTVSWMASENAFDSF 1559
P+ +++V + PS ++ + TA T + + L +D++ ++W + + +
Sbjct: 1695 PTVEYVVSVYAQNPSGESQPLVQTAVTN-IDRPKGLAFTDVDVDSIKIAWESPQGQVSRY 1753
Query: 1560 LVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFTQGHQTKPLRAEIVTEA 1619
VT + G + EL+GL G Y V V +++PL T A
Sbjct: 1754 RVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQST-A 1812
Query: 1620 EPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQSEPLEITLLAPERTRDITG 1679
P +L + TP WT + +++ +K EI L + ++G
Sbjct: 1813 IPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSG 1872
Query: 1680 LREATEYEIELYGISKGRRSQTVSAIATTA--MGSPKEVIFSDITENSATVSWRAPTAQV 1737
L AT+YE+ +Y + S+ + TT + P+ +D TE + T+SWR T +
Sbjct: 1873 LMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETI 1932
Query: 1738 ESFRITYVPITGGTPSMVTVDGTKTQTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTT 1797
F++ VP G TP T+ + L PG +Y + + + S PV +T
Sbjct: 1933 TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1992
Query: 1798 ALDGPSGLVTANITDSEALARWQPAIATVDSYVISY--TGEKVPEITRTVSGNTVEYALT 1855
A+D PS L T + L WQP A + Y+I Y G E+ E +T
Sbjct: 1993 AIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATIT 2052
Query: 1856 DLEPATEYTLRIFAEKGPQKSSTITAKFTTD 1886
LEP TEYT+ + A K QKS + + TD
Sbjct: 2053 GLEPGTEYTIYVIALKNNQKSEPLIGRKKTD 2083
Score = 366 bits (939), Expect = e-100
Identities = 337/1402 (24%), Positives = 598/1402 (42%), Gaps = 82/1402 (5%)
Query: 624 SPPKDLVVTEVTEETVN--LAWD--NEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTII 679
S P ++ +TE + + + W+ +++Y++ + P + G + +PG S I
Sbjct: 609 SGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTI 668
Query: 680 QELEPGVEYFIRVFAILE-------------NKKSIPVSARVATYLPAP------EGLKF 720
+ L+PGV Y ++ +I + S PV++ T P
Sbjct: 669 KGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESV 728
Query: 721 KSIKETSVEVEWDPLDIAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYE 780
I +S V W + + + + DE + L TS L PG++Y
Sbjct: 729 TEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYL-DLPSTATSVNIPDLLPGRKYI 787
Query: 781 ISLH-IVKNNTRGPGLKRVTTTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGI 839
++++ I ++ + L TT DAP V V DT+ ++ W +P A I G + Y
Sbjct: 788 VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYS- 846
Query: 840 KDVPGDRTTIDLTEDENQYSIGNLKPDTEYEVSLISRRGDMSSNPAK-ETFTTG------ 892
V G T ++L E N ++ +L+P +Y +++ + + S P + TTG
Sbjct: 847 PSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDT 906
Query: 893 LDAPRNLRRVSQTDNSITLEWRNGKAAIDSYRIKYAPIS-GGDHAEVDVPKSQQATTKTT 951
+ +PR+L+ V TD +T+ W ++A+ YR+ P++ G+H + +P S+ T
Sbjct: 907 VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQ-RLPISRN--TFAE 963
Query: 952 LTGLRPGTEYGIGVSAVKEDKESNPATINAATELDTPKDLQVSETAETSLTLLWKTPLAK 1011
+TGL PG Y V AV +ES P T T+LD P +LQ ++++ + W P A+
Sbjct: 964 VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQ 1023
Query: 1012 FDRYRLNYSLPT-GQWVGVQLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKAS 1070
YRL L GQ + + + Y LR L+P EY V L A KG +S A +
Sbjct: 1024 ITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFT 1083
Query: 1071 TEQAPELENLTVTEVGWDGLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVD 1130
T Q TEV + + WT A + F + V+ + EA R +T ++
Sbjct: 1084 TLQPGSSIPPYNTEVTETTIVITWTPAPRI--GFKLGVRPSQGGEAPREVTSDSG--SIV 1139
Query: 1131 IPGLKAATPYTVSIYGVIQGYR--TPVLSAEASTGETPNLGEVVVAEVGWDALKLNW--- 1185
+ GL Y +I + G P+++ + T +P + A L ++W
Sbjct: 1140 VSGLTPGVEYVYTIQVLRDGQERDAPIVN-KVVTPLSPPTNLHLEANPDTGVLTVSWERS 1198
Query: 1186 TAPE-GAYEYFFIQV--QEADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDF 1242
T P+ Y Q+ +++E V S L Y +++ V D
Sbjct: 1199 TTPDITGYRITTTPTNGQQGNSLEEV----VHADQSSCTFDNLSPGLEYNVSVYTVKDDK 1254
Query: 1243 STTPLSVEVLTEEVPDMGNLTVTEVSWDALRLNWTTPDG-TYDQFTIQVQEADQVEEAHN 1301
+ P+S + + EVP + +L+ +++ ++ L WT + T + I V A +
Sbjct: 1255 ESVPIS-DTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFE 1313
Query: 1302 LTVPGSLRSMEIPGLRAGTPYTVTLHGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWD 1361
V S+ + GL G Y +++ + G + P + T +P DL + +G D
Sbjct: 1314 DFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTA-VPPPTDLRFTNIGPD 1372
Query: 1362 GLRLNWTAADNA-YEHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGV 1420
+R+ W + +F+++ V E L++ S AV + L T Y VS+ V
Sbjct: 1373 TMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSV 1432
Query: 1421 IRGYRTPVLSAEASTAKEPEIGNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLE 1480
+ + L T + G ++ SDIT SF + W+A + I +
Sbjct: 1433 YEQHESTPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGR 1491
Query: 1481 TVEYNISGAERTAHISGLPPSTDFIVYLSGLAPSIRTKT-ISATATTEALPLLENLTISD 1539
E + + + ++ L P T+++V + L + I +T +P +L +
Sbjct: 1492 PREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVP--RDLEVVA 1549
Query: 1540 INPYGFTVSWMASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMV 1599
P +SW A + +T ++G QEFT+ G++ + GL G+ Y + V
Sbjct: 1550 ATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1609
Query: 1600 SGFT----QGHQTKPLRAEIVTEAEPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIR 1655
T +KP+ TE + + + V+D + + W + ++
Sbjct: 1610 YAVTGRGDSPASSKPISINYRTEID-KPSQMQVTDVQDNSISVKWLPSSSPVTGY--RVT 1666
Query: 1656 DTKKQSE-PLEITLLAPERTR-DITGLREATEYEIELYGISKGRRSQTVSAIATTAMGSP 1713
T K P + P++T I GL+ EY + +Y + SQ + A T + P
Sbjct: 1667 TTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRP 1726
Query: 1714 KEVIFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSMVTV-DGTKTQTRLVKLIPG 1772
K + F+D+ +S ++W +P QV +R+TY G + DG + L L PG
Sbjct: 1727 KGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPG 1786
Query: 1773 VEYLVSIIAMKGFEESEPVSGSFTTALDGPSGLVTANITDSEALARWQPAIATVDSYVIS 1832
EY VS++A+ ES+P+ G+ +TA+ P+ L +T + A+W P + Y +
Sbjct: 1787 SEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVR 1846
Query: 1833 YTGEK----VPEITRTVSGNTVEYALTDLEPATEYTLRIFAEKGPQKSSTITAKFTT--D 1886
T ++ + EI ++V ++ L AT+Y + ++A K S TT +
Sbjct: 1847 VTPKEKTGPMKEINLAPDSSSV--VVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLEN 1904
Query: 1887 LDSPRDLTATEVQSETALLTWRPPRASVTGYLLVYESVDG-TVKEVIVGPDTTSYSLADL 1945
+ PR T+ T ++WR ++TG+ + +G T + + PD SY++ L
Sbjct: 1905 VSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGL 1964
Query: 1946 SPSTHYTAKIQALNGPLRSNMI 1967
P T Y + LN RS+ +
Sbjct: 1965 QPGTDYKIYLYTLNDNARSSPV 1986
Score = 337 bits (863), Expect = 1e-91
Identities = 324/1285 (25%), Positives = 539/1285 (41%), Gaps = 63/1285 (4%)
Query: 623 VSPPKDLVVTEVTEETVNLAW-DNEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTIIQE 681
V P+DL EVT+ V + W E VT Y V P + G Q T +
Sbjct: 907 VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTG 966
Query: 682 LEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPLDIAFET 741
L PGV Y+ +VFA+ ++S P++A+ T L AP L+F + +++V V W P
Sbjct: 967 LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITG 1026
Query: 742 WEIIFRNMNKEDEGEITKSLRRPETS-YRQTGLAPGQEYEISLHIVKNNTRGPGLKRVTT 800
+ + + G+ + P S Y L P EY +SL +K N P V T
Sbjct: 1027 YRL---TVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFT 1083
Query: 801 TRLDAPSQIEV--KDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQY 858
T L S I +VT+TT +ITW P I G +L G++ G ++T D
Sbjct: 1084 T-LQPGSSIPPYNTEVTETTIVITW-TPAPRI-GFKL--GVRPSQGGEAPREVTSDSGSI 1138
Query: 859 SIGNLKPDTEYEVSL-ISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSI-TLEW-RN 915
+ L P EY ++ + R G P T L P NL + D + T+ W R+
Sbjct: 1139 VVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERS 1198
Query: 916 GKAAIDSYRIKYAPISG--GDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKEDKE 973
I YRI P +G G+ E V Q + T L PG EY + V VK+DKE
Sbjct: 1199 TTPDITGYRITTTPTNGQQGNSLEEVVHADQ---SSCTFDNLSPGLEYNVSVYTVKDDKE 1255
Query: 974 SNPATINAATELDTPKDLQVSETAETSLTLLWKTPL--AKFDRYRLNYSLPTGQWVGV-- 1029
S P + E+ DL + ++S+ L W TPL + YR+ + G+ + +
Sbjct: 1256 SVPISDTIIPEVPQLTDLSFVDITDSSIGLRW-TPLNSSTIIGYRITV-VAAGEGIPIFE 1313
Query: 1030 -QLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTEQAPELENLTVTEVGWD 1088
+ + Y + GLEPG +Y++ + +S P + T P + L T +G D
Sbjct: 1314 DFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTD-LRFTNIGPD 1372
Query: 1089 GLRLNWTAADQA-YEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGV 1147
+R+ W +F+++ E L++ S AV + L T Y VS+ V
Sbjct: 1373 TMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSV 1432
Query: 1148 IQGYRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEADTVEA 1207
+ + + L TG G + +++ ++ ++W AP + I+
Sbjct: 1433 YEQHESTPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGR 1491
Query: 1208 AQNLTVPGGLRSTDLPGLKAATHYTITIRGVT-QDFSTTPLSVEVLTEEVPDMGNLTVTE 1266
+ VP S L L T Y ++I + ++ S + + +VP +L V
Sbjct: 1492 PREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVP--RDLEVVA 1549
Query: 1267 VSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTVTL 1326
+ +L ++W P T + I E TVPGS + I GL+ G YT+T+
Sbjct: 1550 ATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1609
Query: 1327 HGEV-RGH---STRPLAVEVVTEDLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQVQ 1382
+ RG S++P+++ TE + + + V++V + + + W + + + +
Sbjct: 1610 YAVTGRGDSPASSKPISINYRTE-IDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTT 1668
Query: 1383 EVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGV-IRGYRTPVLSAEASTAKEPEI 1441
N + T + I GL+ Y VS+Y G P++ + P+
Sbjct: 1669 PKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPK- 1727
Query: 1442 GNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTAHISGLPPS 1501
L +D+ +S ++W + G + + + + G E TA + GL P
Sbjct: 1728 -GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPG 1786
Query: 1502 TDFIVYLSGLAPSIRTKTISATATTEALPLLENLTISDINPYGFTVSWMASENAFDSFLV 1561
+++ V + L + ++ + T +T A+P +L + + P + W + V
Sbjct: 1787 SEYTVSVVALHDDMESQPLIGTQST-AIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRV 1845
Query: 1562 TVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFTQGHQTKPLRAEIVT-EAE 1620
V K +E L+ + + GL+ YEV V ++P + + T E
Sbjct: 1846 RVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENV 1905
Query: 1621 PEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQSEPLEITLLAPERTRDITGL 1680
V+DAT +SW F + Q+ P++ T+ R+ ITGL
Sbjct: 1906 SPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQT-PIQRTIKPDVRSYTITGL 1964
Query: 1681 REATEYEIELYGISKGRRSQTVSAIATTAMGSPKEVIFSDITENSATVSWRAPTAQVESF 1740
+ T+Y+I LY ++ RS V A+TA+ +P + F T NS VSW+ P A++ +
Sbjct: 1965 QPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGY 2024
Query: 1741 RITYVPITGGTPSMVTVDGTK---TQTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTT 1797
I Y G+P V + T+ + L PG EY + +IA+K ++SEP+ G T
Sbjct: 2025 IIKYE--KPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT 2082
Query: 1798 ALDGPSGLVTANITDSEALARWQPAIATVDSYVISYTGEKVPEITRT--VSGNTVEYALT 1855
D LVT + P I V S T +K P +T +GN ++ T
Sbjct: 2083 --DELPQLVTLPHPNLHG-----PEILDVPS-----TVQKTPFVTHPGYDTGNGIQLPGT 2130
Query: 1856 DLEPATEYTLRIFAEKGPQKSSTIT 1880
+ + IF E G ++++ T
Sbjct: 2131 SGQQPSVGQQMIFEEHGFRRTTPPT 2155
Score = 334 bits (856), Expect = 6e-91
Identities = 315/1382 (22%), Positives = 570/1382 (41%), Gaps = 84/1382 (6%)
Query: 631 VTEVTEETVNLAWDNEM-RVTEYLVVYTPTHEGGLEMQFRVPGDQTSTIIQELEPGVEYF 689
VTE+T + ++W + V+ + V Y + EG +P TS I +L PG +Y
Sbjct: 728 VTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYI 787
Query: 690 IRVFAILEN-KKSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPLDIAFETWEIIFRN 748
+ V+ I E+ ++S+ +S T AP + +TS+ V W + I++
Sbjct: 788 VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVY-- 845
Query: 749 MNKEDEGEITKSLRRPETSYRQT--GLAPGQEYEISLHIVKNNTRGPGL----KRVTTTR 802
+ EG T+ L PET+ T L PG +Y I+++ V+ N + + T R
Sbjct: 846 -SPSVEGSSTE-LNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPR 903
Query: 803 LD---APSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQYS 859
D +P ++ +VTD I W P + + G + ++PG+ L N ++
Sbjct: 904 SDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQ-RLPISRNTFA 962
Query: 860 -IGNLKPDTEYEVSLISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSITLEWRNGKA 918
+ L P Y + + S P TT LDAP NL+ V++TD+++ + W +A
Sbjct: 963 EVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRA 1022
Query: 919 AIDSYRIKYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKEDKESNPAT 978
I YR+ G + +V S +K L L+P +EY + + A+K ++ES AT
Sbjct: 1023 QITGYRLTVGLTRRGQPRQYNVGPS---VSKYPLRNLQPASEYTVSLVAIKGNQESPKAT 1079
Query: 979 INAATELDTPKDLQV--SETAETSLTLLWKTPLAKFDRYRLNYSLPTGQWVGVQLPRNTT 1036
T L + +E ET++ + W TP R+ + L G + PR T
Sbjct: 1080 -GVFTTLQPGSSIPPYNTEVTETTIVITW-TPAP-----RIGFKLGVRPSQGGEAPREVT 1132
Query: 1037 S----YVLRGLEPGQEY-NVLLTAEKGRHKSKPARVKASTEQAPELE-------NLTVTE 1084
S V+ GL PG EY + G+ + P K T +P + V
Sbjct: 1133 SDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLT 1192
Query: 1085 VGWD--------GLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKA 1136
V W+ G R+ T + + + +V A++ + PG
Sbjct: 1193 VSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPG------------ 1240
Query: 1137 ATPYTVSIYGVIQGYRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWTAPEGA--YEY 1194
Y VS+Y ++ + V ++ E P L ++ ++ ++ L WT + Y
Sbjct: 1241 -LEYNVSVY-TVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGY 1298
Query: 1195 FFIQVQEADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLTE 1254
V + + ++ V + + GL+ Y I++ + + P ++ T
Sbjct: 1299 RITVVAAGEGIPIFEDF-VDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTA 1357
Query: 1255 EVPDMGNLTVTEVSWDALRLNWTTPDGT-YDQFTIQVQEADQVEEAHNLTVPGSLRSMEI 1313
VP +L T + D +R+ W P F ++ E+ L++ S ++ +
Sbjct: 1358 -VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL 1416
Query: 1314 PGLRAGTPYTVTLHGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWDGLRLNWTAADNA 1373
L GT Y V++ H + PL T L + S++ + ++W A
Sbjct: 1417 TNLLPGTEYVVSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFSDITANSFTVHWIAPRAT 1475
Query: 1374 YEHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEA 1433
+ I+ + + +P S ++ + L T Y VSI + +P+L +
Sbjct: 1476 ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQ 1535
Query: 1434 STAKEPEIGNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTA 1493
ST + +L V TP S +SW A + I ++ E+ + G++ TA
Sbjct: 1536 STVSDVP-RDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1594
Query: 1494 HISGLPPSTDFIVYL-----SGLAPSIRTKTISATATTEALPLLENLTISDINPYGFTVS 1548
ISGL P D+ + + G +P+ +K IS TE + + ++D+ +V
Sbjct: 1595 TISGLKPGVDYTITVYAVTGRGDSPA-SSKPISINYRTE-IDKPSQMQVTDVQDNSISVK 1652
Query: 1549 WMASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFTQGHQT 1608
W+ S + + VT + T Q ++ + GL + Y V V ++
Sbjct: 1653 WLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGES 1712
Query: 1609 KPLRAEIVTEAEPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQSEPLEITL 1668
+PL VT + L +D D +++W + +G + + + L
Sbjct: 1713 QPLVQTAVTNID-RPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAP 1771
Query: 1669 LAPERTRDITGLREATEYEIELYGISKGRRSQTVSAIATTAMGSPKEVIFSDITENSATV 1728
E T ++ GLR +EY + + + SQ + +TA+ +P ++ F+ +T S +
Sbjct: 1772 DGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSA 1831
Query: 1729 SWRAPTAQVESFRITYVPITGGTPSM-VTVDGTKTQTRLVKLIPGVEYLVSIIAMKGFEE 1787
W P Q+ +R+ P P + + + + L+ +Y VS+ A+K
Sbjct: 1832 QWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLT 1891
Query: 1788 SEPVSGSFTTA--LDGPSGLVTANITDSEALARWQPAIATVDSYVI-SYTGEKVPEITRT 1844
S P G TT + P + T++ W+ T+ + + + I RT
Sbjct: 1892 SRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRT 1951
Query: 1845 VSGNTVEYALTDLEPATEYTLRIFAEKGPQKSSTITAKFTTDLDSPRDLTATEVQSETAL 1904
+ + Y +T L+P T+Y + ++ +SS + +T +D+P +L + L
Sbjct: 1952 IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLL 2011
Query: 1905 LTWRPPRASVTGYLLVYESVDGTVKEVI--VGPDTTSYSLADLSPSTHYTAKIQALNGPL 1962
++W+PPRA +TGY++ YE +EV+ P T ++ L P T YT + AL
Sbjct: 2012 VSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQ 2071
Query: 1963 RS 1964
+S
Sbjct: 2072 KS 2073
Score = 314 bits (805), Expect = 5e-85
Identities = 310/1276 (24%), Positives = 535/1276 (41%), Gaps = 96/1276 (7%)
Query: 767 SYRQTGLAPGQEYEISLHIVKN--------------NTRGPGLKRVTTTRLDAPSQI--- 809
SY GL PG YE L ++ +T P T S +
Sbjct: 665 SYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVAT 724
Query: 810 --EVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQYSIGNLKPDT 867
V ++T ++ +++W + G + Y + + + +DL +I +L P
Sbjct: 725 SESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGR 784
Query: 868 EYEVSL--ISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSITLEWRNGKAAIDSYRI 925
+Y V++ IS G+ S + TT DAP + D SI + W +A I YRI
Sbjct: 785 KYIVNVYQISEDGEQSLILSTSQ-TTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRI 843
Query: 926 KYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKEDKESNPATINAATE- 984
Y+P G E+++P++ + T L+ L+PG +Y I + AV+E++ES P I T
Sbjct: 844 VYSPSVEGSSTELNLPETANSVT---LSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
Query: 985 ------LDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNY---SLPTGQWVGVQLPRNT 1035
+ +P+DLQ E + +T++W P + YR++ +LP + + RNT
Sbjct: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
Query: 1036 TSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTE-QAPELENLTVTEVGWDGLRLNW 1094
+ V GL PG Y + A +SKP + +T+ AP NL + + W
Sbjct: 961 FAEVT-GLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPT--NLQFVNETDSTVLVRW 1017
Query: 1095 TAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVIQGYRTP 1154
T + + V + + R V S+ + L+ A+ YTVS+ + +P
Sbjct: 1018 TPPRAQITGYRLTVGLTRRGQP-RQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESP 1076
Query: 1155 VLSAEASTGETPNLGEVVVAEVGWDALKLNWT-APEGAYEYFFIQVQEADTVEAAQNLTV 1213
+ +T + + EV + + WT AP ++ + V+ + EA + +T
Sbjct: 1077 KATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFK---LGVRPSQGGEAPREVTS 1133
Query: 1214 PGGLRSTDLPGLKAATHYTITIR----GVTQDFS-----TTPLS--VEVLTEEVPDMGNL 1262
G S + GL Y TI+ G +D TPLS + E PD G L
Sbjct: 1134 DSG--SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVL 1191
Query: 1263 TVTEVSWDALRLNWTTPDGTYDQFTIQV---QEADQVEEAHNLTVPGSLRSMEIPGLRAG 1319
TV SW+ TTPD T + T Q+ + +EE V S L G
Sbjct: 1192 TV---SWERS----TTPDITGYRITTTPTNGQQGNSLEEV----VHADQSSCTFDNLSPG 1240
Query: 1320 TPYTVTLHGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVI 1379
Y V+++ + P++ ++ E +PQL DL+ ++ + L WT +++ I
Sbjct: 1241 LEYNVSVYTVKDDKESVPISDTIIPE-VPQLTDLSFVDITDSSIGLRWTPLNSS----TI 1295
Query: 1380 QVQEVNKVEAAQNLTL-----PGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEAS 1434
+ V A + + + S+ + GLE Y +S+ +I G + +
Sbjct: 1296 IGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQ 1355
Query: 1435 TAKEPEIGNLNVSDITPESFNLSWMATDGIFET-FTIEIIDSNRLLETVEYNISGAERTA 1493
TA P +L ++I P++ ++W I T F + + E +IS ++
Sbjct: 1356 TAVPPPT-DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAV 1414
Query: 1494 HISGLPPSTDFIVYLSGLAPSIRTKTISATATTEALPLLENLTISDINPYGFTVSWMASE 1553
++ L P T+++V +S + + + T L + SDI FTV W+A
Sbjct: 1415 VLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFSDITANSFTVHWIAPR 1473
Query: 1554 NAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFTQGHQTKPLRA 1613
+ + P+E + ++ + L L G Y V + G + PL
Sbjct: 1474 ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN-GREESPLLI 1532
Query: 1614 EIVTEAEPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQSEPLEITLLAPER 1673
+ +L V ATP +SW A + + +T S E T+ +
Sbjct: 1533 GQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKS 1592
Query: 1674 TRDITGLREATEYEIELYGISKGR-----RSQTVSAIATTAMGSPKEVIFSDITENSATV 1728
T I+GL+ +Y I +Y ++ GR S+ +S T + P ++ +D+ +NS +V
Sbjct: 1593 TATISGLKPGVDYTITVYAVT-GRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1651
Query: 1729 SWRAPTAQVESFRITYVPITGGTPSMVTVDGT-KTQTRLVKLIPGVEYLVSIIAMKGFEE 1787
W ++ V +R+T P G P+ G +T+ + L P VEY+VS+ A E
Sbjct: 1652 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1711
Query: 1788 SEPVSGSFTTALDGPSGLVTANITDSEALARWQPAIATVDSYVISYTGEK--VPEITRTV 1845
S+P+ + T +D P GL ++ W+ V Y ++Y+ + + E+
Sbjct: 1712 SQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAP 1771
Query: 1846 SGNTVEYALTDLEPATEYTLRIFAEKGPQKSSTITAKFTTDLDSPRDLTATEVQSETALL 1905
G L L P +EYT+ + A +S + +T + +P DL T+V +
Sbjct: 1772 DGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSA 1831
Query: 1906 TWRPPRASVTGYLL--VYESVDGTVKEVIVGPDTTSYSLADLSPSTHYTAKIQALNGPLR 1963
W PP +TGY + + G +KE+ + PD++S ++ L +T Y + AL L
Sbjct: 1832 QWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLT 1891
Query: 1964 SNMIQTIFTTIGLLYP 1979
S Q + TT+ + P
Sbjct: 1892 SRPAQGVVTTLENVSP 1907
Score = 221 bits (564), Expect = 5e-57
Identities = 247/1093 (22%), Positives = 427/1093 (39%), Gaps = 117/1093 (10%)
Query: 622 EVSPPKDLVVTEVTEETVNLAWD--NEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTII 679
EV DL ++T+ ++ L W N + Y + EG + V +
Sbjct: 1266 EVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTV 1325
Query: 680 QELEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPLDIAF 739
LEPG++Y I V ++ +S P + T +P P L+F +I ++ V W P
Sbjct: 1326 TGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSID 1385
Query: 740 ETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNNTRGPGLKRVT 799
T ++ + K +E S+ + + T L PG EY +S+ V L+
Sbjct: 1386 LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ 1445
Query: 800 TTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQYS 859
T LD+P+ I+ D+T + + W P A I G + + + G + N +
Sbjct: 1446 KTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSIT 1505
Query: 860 IGNLKPDTEYEVSLISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSITLEWRNGKAA 919
+ NL P TEY VS+++ G S +T D PR+L V+ T S+ + W
Sbjct: 1506 LTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT 1565
Query: 920 IDSYRIKYAPISGGDHA-EVDVPKSQQATTKTTLTGLRPGTEYGIGVSAV----KEDKES 974
+ YRI Y G E VP S+ + T++GL+PG +Y I V AV S
Sbjct: 1566 VRYYRITYGETGGNSPVQEFTVPGSK---STATISGLKPGVDYTITVYAVTGRGDSPASS 1622
Query: 975 NPATINAATELDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYSLPTGQWVGVQLPRN 1034
P +IN TE+D P +QV++ + S+++ W + YR+ + G P
Sbjct: 1623 KPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPG-----PTK 1677
Query: 1035 T-------TSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTEQAPELENLTVTEVGW 1087
T T + GL+P EY V + A+ +S+P V+ + + L T+V
Sbjct: 1678 TKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL-VQTAVTNIDRPKGLAFTDVDV 1736
Query: 1088 DGLRLNWTAADQAYEHFIIQVQEANKVEAARNL--TVPGSLRAVDIPGLKAATPYTVSIY 1145
D +++ W + + +V ++ + L G ++ GL+ + YTVS+
Sbjct: 1737 DSIKIAWESPQGQVSRY--RVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVV 1794
Query: 1146 GVIQGYRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEADTV 1205
+ + L ST P ++ +V +L WT P + ++V +
Sbjct: 1795 ALHDDMESQPLIGTQSTA-IPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKT 1853
Query: 1206 EAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLT-EEVPDMGNLTV 1264
+ + + S + GL AT Y +++ + ++ P V T E V V
Sbjct: 1854 GPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARV 1913
Query: 1265 TEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTV 1324
T+ + + ++W T T F + A+ + T+ +RS I GL+ GT Y +
Sbjct: 1914 TDATETTITISWRTKTETITGFQVDAVPANG-QTPIQRTIKPDVRSYTITGLQPGTDYKI 1972
Query: 1325 TLHGEVRGHSTRPLAVEVVTE-DLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQVQE 1383
L+ + P+ ++ T D P +L + L ++W ++I+ ++
Sbjct: 1973 YLYTLNDNARSSPVVIDASTAIDAP--SNLRFLATTPNSLLVSWQPPRARITGYIIKYEK 2030
Query: 1384 V-NKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEASTAKEPEIG 1442
+ PG A I GLE T Y +IY V++ + + EP IG
Sbjct: 2031 PGSPPREVVPRPRPGVTEAT-ITGLEPGTEY--TIY---------VIALKNNQKSEPLIG 2078
Query: 1443 NLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTAHISGLPPST 1502
++ P+ L G EI+D ++ + T + LP +
Sbjct: 2079 RKKTDEL-PQLVTLPHPNLHG------PEILDVPSTVQKTPFVTHPGYDTGNGIQLPGT- 2130
Query: 1503 DFIVYLSGLAPSIRTKTI-------SATATTEALPLL-----------ENLTISDI---- 1540
SG PS+ + I T T A P+ E + I I
Sbjct: 2131 ------SGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGEEIQIGHIPRED 2184
Query: 1541 ------------NPYGFT---------VSWMASENAFDSFLVTVVDSGKLLDPQEFTLSG 1579
NP T +SW ++ ++++ G +P +F + G
Sbjct: 2185 VDYHLYPHGPGLNPNASTGQEALSQTTISWAPFQDT-SEYIISCHPVGTDEEPLQFRVPG 2243
Query: 1580 TQRKLELRGLITGIGYEVMVSGFTQGHQTKPLRAEIVTEAEPEVDNLLVSDATPDGFRLS 1639
T L GL G Y ++V + Q +R E+VT V ++ +G L+
Sbjct: 2244 TSTSATLTGLTRGATYNIIVEAL-KDQQRHKVREEVVT----------VGNSVNEG--LN 2290
Query: 1640 WTADEGVFDNFVL 1652
D+ FD + +
Sbjct: 2291 QPTDDSCFDPYTV 2303
Score = 213 bits (541), Expect = 2e-54
Identities = 156/656 (23%), Positives = 288/656 (43%), Gaps = 17/656 (2%)
Query: 617 GEDCSEVSPPKDLVVTEVTEETVNLAW-DNEMRVTEYLVVYTPTHEGGLEMQFRVPGDQT 675
G + + P + +++T + + W +T Y + + P H G + RVP +
Sbjct: 1443 GRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRN 1502
Query: 676 STIIQELEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPL 735
S + L PG EY + + A+ ++S + + +T P L+ + TS+ + WD
Sbjct: 1503 SITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP 1562
Query: 736 DIAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNNTRGPGL 795
+ + I + + ++ +++ +GL PG +Y I+++ V P
Sbjct: 1563 AVTVRYYRITYGETGGNSPVQ-EFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPAS 1621
Query: 796 KRVTT----TRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDL 851
+ + T +D PSQ++V DV D + + W + + G +T K+ PG T
Sbjct: 1622 SKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTA 1681
Query: 852 TEDENQYSIGNLKPDTEYEVSLISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSITL 911
D+ + +I L+P EY VS+ ++ S P +T T +D P+ L +SI +
Sbjct: 1682 GPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKI 1741
Query: 912 EWRNGKAAIDSYRIKYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKED 971
W + + + YR+ Y+ G H P ++ T + L GLRPG+EY + V A+ +D
Sbjct: 1742 AWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAE--LQGLRPGSEYTVSVVALHDD 1799
Query: 972 KESNPATINAATELDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYS--LPTGQWVGV 1029
ES P +T + P DL+ ++ TSL+ W P + YR+ + TG +
Sbjct: 1800 MESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEI 1859
Query: 1030 QLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPAR-VKASTEQAPELENLTVTEVGWD 1088
L +++S V+ GL +Y V + A K S+PA+ V + E VT+
Sbjct: 1860 NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATET 1919
Query: 1089 GLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVI 1148
+ ++W + F + AN + T+ +R+ I GL+ T Y + +Y +
Sbjct: 1920 TITISWRTKTETITGFQVDAVPANG-QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1978
Query: 1149 QGYRTPVLSAEASTG-ETP-NLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEADTVE 1206
R+ + +AST + P NL + ++L ++W P + I+ ++ +
Sbjct: 1979 DNARSSPVVIDASTAIDAPSNLRFLATTP---NSLLVSWQPPRARITGYIIKYEKPGSPP 2035
Query: 1207 AAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLTEEVPDMGNL 1262
G+ + GL+ T YTI + + + + PL T+E+P + L
Sbjct: 2036 REVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTL 2091
Score = 152 bits (385), Expect = 3e-36
Identities = 152/694 (21%), Positives = 275/694 (39%), Gaps = 47/694 (6%)
Query: 1365 LNWTAADNAY-EHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIR- 1422
+ W A ++ ++++ + N V + T+PG L + I GL+ Y + + +
Sbjct: 628 IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687
Query: 1423 GYR-------------TPVLSAEASTAKEP----EIGNLNVSDITPESFNLSWMATDGIF 1465
G++ TPV S + P + +V++IT SF +SW++
Sbjct: 688 GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747
Query: 1466 ETFTIEIIDSNRLLETVEYNISGAERTAHISGLPPSTDFIVYLSGLAPSIRTKTISATAT 1525
F +E S E ++ + +I L P +IV + ++ I +T+
Sbjct: 748 SGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQ 807
Query: 1526 TEALPLLENLTISDINPYGFTVSWMASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLE 1585
T A + T+ ++ V W + + + S + E L T +
Sbjct: 808 TTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEG-SSTELNLPETANSVT 866
Query: 1586 LRGLITGIGYEVMVSGFTQGHQTKPLRAEIVTEAEPEVD------NLLVSDATPDGFRLS 1639
L L G+ Y + + + ++ P+ + T P D +L + T +
Sbjct: 867 LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926
Query: 1640 WTADEGVFDNFVLKIRDTKKQSEPLEITLLAPERTRDITGLREATEYEIELYGISKGRRS 1699
WT E + + + E + ++ ++TGL Y +++ +S GR S
Sbjct: 927 WTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986
Query: 1700 QTVSAIATTAMGSPKEVIFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSMVTVDG 1759
+ ++A TT + +P + F + T+++ V W P AQ+ +R+T G P V
Sbjct: 987 KPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGP 1046
Query: 1760 TKTQTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTTALDGPS-GLVTANITDSEALAR 1818
+ ++ L L P EY VS++A+KG +ES +G FTT G S +T++ +
Sbjct: 1047 SVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVIT 1106
Query: 1819 WQPAIATVDSYVISYTGEKVPEITRTVSGNTVEYALTDLEPATEYTLRI-FAEKGPQKSS 1877
W PA + + + E R V+ ++ ++ L P EY I G ++ +
Sbjct: 1107 WTPAPRI--GFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDA 1164
Query: 1878 TITAKFTTDLDSPRDLTATEVQSETALLT--W-RPPRASVTGYLLVYESVD---GTVKEV 1931
I K T L P +L E +T +LT W R +TGY + + G E
Sbjct: 1165 PIVNKVVTPLSPPTNL-HLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEE 1223
Query: 1932 IVGPDTTSYSLADLSPSTHYTAKIQALNG-----PLRSNMIQTIFTTIGLLYPFPKDCSQ 1986
+V D +S + +LSP Y + + P+ +I + L + D S
Sbjct: 1224 VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSI 1283
Query: 1987 AM----LNGDTTSGL-YTIYLNGDKAEALEVFCD 2015
+ LN T G T+ G+ E F D
Sbjct: 1284 GLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVD 1317
>gi|47132551 fibronectin 1 isoform 2 preproprotein [Homo sapiens]
Length = 2421
Score = 379 bits (973), Expect = e-104
Identities = 314/1295 (24%), Positives = 543/1295 (41%), Gaps = 51/1295 (3%)
Query: 626 PKDLVVTEVTEETVNLAWDN-EMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTIIQELEP 684
P D V +V + ++ + W + +T Y +VY+P+ EG + +P S + +L+P
Sbjct: 814 PPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGS-STELNLPETANSVTLSDLQP 872
Query: 685 GVEYFIRVFAILENKKSIPVSARVATY-------LPAPEGLKFKSIKETSVEVEWDPLDI 737
GV+Y I ++A+ EN++S PV + T +P+P L+F + + V + W P +
Sbjct: 873 GVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES 932
Query: 738 AFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNNTRGPGLKR 797
A + + +N E + R T TGL+PG Y + V + L
Sbjct: 933 AVTGYRVDVIPVNLPGEHGQRLPISR-NTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTA 991
Query: 798 VTTTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQ 857
TT+LDAP+ ++ + TD+T L+ W P A+I G LT G+ G ++ ++
Sbjct: 992 QQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTR-RGQPRQYNVGPSVSK 1050
Query: 858 YSIGNLKPDTEYEVSLISRRGDMSSNPAKETFTT---GLDAPRNLRRVSQTDNSITLEWR 914
Y + NL+P +EY VSL++ +G+ S A FTT G P V++T +I + W
Sbjct: 1051 YPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTET--TIVITWT 1108
Query: 915 NGKAAIDSYRIKYAPISGGDHAEVDVPKSQQATTKT-TLTGLRPGTEYGIGVSAVKEDKE 973
A +++ P GG+ P+ + + + ++GL PG EY + +++ +E
Sbjct: 1109 --PAPRIGFKLGVRPSQGGE-----APREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQE 1161
Query: 974 SNPATIN-AATELDTPKDLQVSETAETS-LTLLW-KTPLAKFDRYRLNYSLPTGQWVGVQ 1030
+ +N T L P +L + +T LT+ W ++ YR+ + PT G
Sbjct: 1162 RDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRIT-TTPTNGQQGNS 1220
Query: 1031 LPR----NTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTEQAPELENLTVTEVG 1086
L + +S L PG EYNV + K +S P E P+L +L+ ++
Sbjct: 1221 LEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPE-VPQLTDLSFVDIT 1279
Query: 1087 WDGLRLNWTAADQA-YEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIY 1145
+ L WT + + + I V A + V S+ + GL+ Y +S+
Sbjct: 1280 DSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVI 1339
Query: 1146 GVIQGYRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWTAPEGA-YEYFFIQVQEADT 1204
+I G + + T P ++ +G D +++ W P F ++
Sbjct: 1340 TLINGGESAPTTLTQQTAVPPPT-DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKN 1398
Query: 1205 VEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLTEEVPDMGNLTV 1264
E L++ + L L T Y +++ V + +TPL T G +
Sbjct: 1399 EEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTG-IDF 1457
Query: 1265 TEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTV 1324
++++ ++ ++W P T + I+ VP S S+ + L GT Y V
Sbjct: 1458 SDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVV 1517
Query: 1325 TLHGEVRGHSTRPLAV--EVVTEDLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQVQ 1382
++ + G PL + + D+P+ DL V L ++W A ++ I
Sbjct: 1518 SIVA-LNGREESPLLIGQQSTVSDVPR--DLEVVAATPTSLLISWDAPAVTVRYYRITYG 1574
Query: 1383 EVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEASTAKEPEI- 1441
E Q T+PGS I GL+ Y +++Y V +P S S EI
Sbjct: 1575 ETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1634
Query: 1442 --GNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTAHISGLP 1499
+ V+D+ S ++ W+ + + + N T + I GL
Sbjct: 1635 KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1694
Query: 1500 PSTDFIVYLSGLAPSIRTKTISATATTEALPLLENLTISDINPYGFTVSWMASENAFDSF 1559
P+ +++V + PS ++ + TA T + + L +D++ ++W + + +
Sbjct: 1695 PTVEYVVSVYAQNPSGESQPLVQTAVTN-IDRPKGLAFTDVDVDSIKIAWESPQGQVSRY 1753
Query: 1560 LVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFTQGHQTKPLRAEIVTEA 1619
VT + G + EL+GL G Y V V +++PL T A
Sbjct: 1754 RVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQST-A 1812
Query: 1620 EPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQSEPLEITLLAPERTRDITG 1679
P +L + TP WT + +++ +K EI L + ++G
Sbjct: 1813 IPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSG 1872
Query: 1680 LREATEYEIELYGISKGRRSQTVSAIATTA--MGSPKEVIFSDITENSATVSWRAPTAQV 1737
L AT+YE+ +Y + S+ + TT + P+ +D TE + T+SWR T +
Sbjct: 1873 LMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETI 1932
Query: 1738 ESFRITYVPITGGTPSMVTVDGTKTQTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTT 1797
F++ VP G TP T+ + L PG +Y + + + S PV +T
Sbjct: 1933 TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1992
Query: 1798 ALDGPSGLVTANITDSEALARWQPAIATVDSYVISY--TGEKVPEITRTVSGNTVEYALT 1855
A+D PS L T + L WQP A + Y+I Y G E+ E +T
Sbjct: 1993 AIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATIT 2052
Query: 1856 DLEPATEYTLRIFAEKGPQKSSTITAKFTTDLDSP 1890
LEP TEYT+ + A K QKS + + T +P
Sbjct: 2053 GLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTP 2087
Score = 366 bits (939), Expect = e-100
Identities = 337/1402 (24%), Positives = 598/1402 (42%), Gaps = 82/1402 (5%)
Query: 624 SPPKDLVVTEVTEETVN--LAWD--NEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTII 679
S P ++ +TE + + + W+ +++Y++ + P + G + +PG S I
Sbjct: 609 SGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTI 668
Query: 680 QELEPGVEYFIRVFAILE-------------NKKSIPVSARVATYLPAP------EGLKF 720
+ L+PGV Y ++ +I + S PV++ T P
Sbjct: 669 KGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESV 728
Query: 721 KSIKETSVEVEWDPLDIAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYE 780
I +S V W + + + + DE + L TS L PG++Y
Sbjct: 729 TEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYL-DLPSTATSVNIPDLLPGRKYI 787
Query: 781 ISLH-IVKNNTRGPGLKRVTTTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGI 839
++++ I ++ + L TT DAP V V DT+ ++ W +P A I G + Y
Sbjct: 788 VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYS- 846
Query: 840 KDVPGDRTTIDLTEDENQYSIGNLKPDTEYEVSLISRRGDMSSNPAK-ETFTTG------ 892
V G T ++L E N ++ +L+P +Y +++ + + S P + TTG
Sbjct: 847 PSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDT 906
Query: 893 LDAPRNLRRVSQTDNSITLEWRNGKAAIDSYRIKYAPIS-GGDHAEVDVPKSQQATTKTT 951
+ +PR+L+ V TD +T+ W ++A+ YR+ P++ G+H + +P S+ T
Sbjct: 907 VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQ-RLPISRN--TFAE 963
Query: 952 LTGLRPGTEYGIGVSAVKEDKESNPATINAATELDTPKDLQVSETAETSLTLLWKTPLAK 1011
+TGL PG Y V AV +ES P T T+LD P +LQ ++++ + W P A+
Sbjct: 964 VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQ 1023
Query: 1012 FDRYRLNYSLPT-GQWVGVQLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKAS 1070
YRL L GQ + + + Y LR L+P EY V L A KG +S A +
Sbjct: 1024 ITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFT 1083
Query: 1071 TEQAPELENLTVTEVGWDGLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVD 1130
T Q TEV + + WT A + F + V+ + EA R +T ++
Sbjct: 1084 TLQPGSSIPPYNTEVTETTIVITWTPAPRI--GFKLGVRPSQGGEAPREVTSDSG--SIV 1139
Query: 1131 IPGLKAATPYTVSIYGVIQGYR--TPVLSAEASTGETPNLGEVVVAEVGWDALKLNW--- 1185
+ GL Y +I + G P+++ + T +P + A L ++W
Sbjct: 1140 VSGLTPGVEYVYTIQVLRDGQERDAPIVN-KVVTPLSPPTNLHLEANPDTGVLTVSWERS 1198
Query: 1186 TAPE-GAYEYFFIQV--QEADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDF 1242
T P+ Y Q+ +++E V S L Y +++ V D
Sbjct: 1199 TTPDITGYRITTTPTNGQQGNSLEEV----VHADQSSCTFDNLSPGLEYNVSVYTVKDDK 1254
Query: 1243 STTPLSVEVLTEEVPDMGNLTVTEVSWDALRLNWTTPDG-TYDQFTIQVQEADQVEEAHN 1301
+ P+S + + EVP + +L+ +++ ++ L WT + T + I V A +
Sbjct: 1255 ESVPIS-DTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFE 1313
Query: 1302 LTVPGSLRSMEIPGLRAGTPYTVTLHGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWD 1361
V S+ + GL G Y +++ + G + P + T +P DL + +G D
Sbjct: 1314 DFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTA-VPPPTDLRFTNIGPD 1372
Query: 1362 GLRLNWTAADNA-YEHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGV 1420
+R+ W + +F+++ V E L++ S AV + L T Y VS+ V
Sbjct: 1373 TMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSV 1432
Query: 1421 IRGYRTPVLSAEASTAKEPEIGNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLE 1480
+ + L T + G ++ SDIT SF + W+A + I +
Sbjct: 1433 YEQHESTPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGR 1491
Query: 1481 TVEYNISGAERTAHISGLPPSTDFIVYLSGLAPSIRTKT-ISATATTEALPLLENLTISD 1539
E + + + ++ L P T+++V + L + I +T +P +L +
Sbjct: 1492 PREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVP--RDLEVVA 1549
Query: 1540 INPYGFTVSWMASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMV 1599
P +SW A + +T ++G QEFT+ G++ + GL G+ Y + V
Sbjct: 1550 ATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1609
Query: 1600 SGFT----QGHQTKPLRAEIVTEAEPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIR 1655
T +KP+ TE + + + V+D + + W + ++
Sbjct: 1610 YAVTGRGDSPASSKPISINYRTEID-KPSQMQVTDVQDNSISVKWLPSSSPVTGY--RVT 1666
Query: 1656 DTKKQSE-PLEITLLAPERTR-DITGLREATEYEIELYGISKGRRSQTVSAIATTAMGSP 1713
T K P + P++T I GL+ EY + +Y + SQ + A T + P
Sbjct: 1667 TTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRP 1726
Query: 1714 KEVIFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSMVTV-DGTKTQTRLVKLIPG 1772
K + F+D+ +S ++W +P QV +R+TY G + DG + L L PG
Sbjct: 1727 KGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPG 1786
Query: 1773 VEYLVSIIAMKGFEESEPVSGSFTTALDGPSGLVTANITDSEALARWQPAIATVDSYVIS 1832
EY VS++A+ ES+P+ G+ +TA+ P+ L +T + A+W P + Y +
Sbjct: 1787 SEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVR 1846
Query: 1833 YTGEK----VPEITRTVSGNTVEYALTDLEPATEYTLRIFAEKGPQKSSTITAKFTT--D 1886
T ++ + EI ++V ++ L AT+Y + ++A K S TT +
Sbjct: 1847 VTPKEKTGPMKEINLAPDSSSV--VVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLEN 1904
Query: 1887 LDSPRDLTATEVQSETALLTWRPPRASVTGYLLVYESVDG-TVKEVIVGPDTTSYSLADL 1945
+ PR T+ T ++WR ++TG+ + +G T + + PD SY++ L
Sbjct: 1905 VSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGL 1964
Query: 1946 SPSTHYTAKIQALNGPLRSNMI 1967
P T Y + LN RS+ +
Sbjct: 1965 QPGTDYKIYLYTLNDNARSSPV 1986
Score = 337 bits (865), Expect = 6e-92
Identities = 310/1230 (25%), Positives = 516/1230 (41%), Gaps = 53/1230 (4%)
Query: 623 VSPPKDLVVTEVTEETVNLAW-DNEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTIIQE 681
V P+DL EVT+ V + W E VT Y V P + G Q T +
Sbjct: 907 VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTG 966
Query: 682 LEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPLDIAFET 741
L PGV Y+ +VFA+ ++S P++A+ T L AP L+F + +++V V W P
Sbjct: 967 LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITG 1026
Query: 742 WEIIFRNMNKEDEGEITKSLRRPETS-YRQTGLAPGQEYEISLHIVKNNTRGPGLKRVTT 800
+ + + G+ + P S Y L P EY +SL +K N P V T
Sbjct: 1027 YRL---TVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFT 1083
Query: 801 TRLDAPSQIEV--KDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQY 858
T L S I +VT+TT +ITW P I G +L G++ G ++T D
Sbjct: 1084 T-LQPGSSIPPYNTEVTETTIVITW-TPAPRI-GFKL--GVRPSQGGEAPREVTSDSGSI 1138
Query: 859 SIGNLKPDTEYEVSL-ISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSI-TLEW-RN 915
+ L P EY ++ + R G P T L P NL + D + T+ W R+
Sbjct: 1139 VVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERS 1198
Query: 916 GKAAIDSYRIKYAPISG--GDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKEDKE 973
I YRI P +G G+ E V Q + T L PG EY + V VK+DKE
Sbjct: 1199 TTPDITGYRITTTPTNGQQGNSLEEVVHADQ---SSCTFDNLSPGLEYNVSVYTVKDDKE 1255
Query: 974 SNPATINAATELDTPKDLQVSETAETSLTLLWKTPL--AKFDRYRLNYSLPTGQWVGV-- 1029
S P + E+ DL + ++S+ L W TPL + YR+ + G+ + +
Sbjct: 1256 SVPISDTIIPEVPQLTDLSFVDITDSSIGLRW-TPLNSSTIIGYRITV-VAAGEGIPIFE 1313
Query: 1030 -QLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTEQAPELENLTVTEVGWD 1088
+ + Y + GLEPG +Y++ + +S P + T P + L T +G D
Sbjct: 1314 DFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTD-LRFTNIGPD 1372
Query: 1089 GLRLNWTAADQA-YEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGV 1147
+R+ W +F+++ E L++ S AV + L T Y VS+ V
Sbjct: 1373 TMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSV 1432
Query: 1148 IQGYRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEADTVEA 1207
+ + + L TG G + +++ ++ ++W AP + I+
Sbjct: 1433 YEQHESTPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGR 1491
Query: 1208 AQNLTVPGGLRSTDLPGLKAATHYTITIRGVT-QDFSTTPLSVEVLTEEVPDMGNLTVTE 1266
+ VP S L L T Y ++I + ++ S + + +VP +L V
Sbjct: 1492 PREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVP--RDLEVVA 1549
Query: 1267 VSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTVTL 1326
+ +L ++W P T + I E TVPGS + I GL+ G YT+T+
Sbjct: 1550 ATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1609
Query: 1327 HGEV-RGH---STRPLAVEVVTEDLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQVQ 1382
+ RG S++P+++ TE + + + V++V + + + W + + + +
Sbjct: 1610 YAVTGRGDSPASSKPISINYRTE-IDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTT 1668
Query: 1383 EVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGV-IRGYRTPVLSAEASTAKEPEI 1441
N + T + I GL+ Y VS+Y G P++ + P+
Sbjct: 1669 PKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPK- 1727
Query: 1442 GNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTAHISGLPPS 1501
L +D+ +S ++W + G + + + + G E TA + GL P
Sbjct: 1728 -GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPG 1786
Query: 1502 TDFIVYLSGLAPSIRTKTISATATTEALPLLENLTISDINPYGFTVSWMASENAFDSFLV 1561
+++ V + L + ++ + T +T A+P +L + + P + W + V
Sbjct: 1787 SEYTVSVVALHDDMESQPLIGTQST-AIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRV 1845
Query: 1562 TVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFTQGHQTKPLRAEIVT-EAE 1620
V K +E L+ + + GL+ YEV V ++P + + T E
Sbjct: 1846 RVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENV 1905
Query: 1621 PEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQSEPLEITLLAPERTRDITGL 1680
V+DAT +SW F + Q+ P++ T+ R+ ITGL
Sbjct: 1906 SPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQT-PIQRTIKPDVRSYTITGL 1964
Query: 1681 REATEYEIELYGISKGRRSQTVSAIATTAMGSPKEVIFSDITENSATVSWRAPTAQVESF 1740
+ T+Y+I LY ++ RS V A+TA+ +P + F T NS VSW+ P A++ +
Sbjct: 1965 QPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGY 2024
Query: 1741 RITYVPITGGTPSMVTVDGTK---TQTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTT 1797
I Y G+P V + T+ + L PG EY + +IA+K ++SEP+ G T
Sbjct: 2025 IIKYE--KPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT 2082
Query: 1798 ALDGP----SGLVTANITDSEALARWQPAI 1823
P G T N + QP++
Sbjct: 2083 VQKTPFVTHPGYDTGNGIQLPGTSGQQPSV 2112
Score = 334 bits (856), Expect = 6e-91
Identities = 315/1382 (22%), Positives = 570/1382 (41%), Gaps = 84/1382 (6%)
Query: 631 VTEVTEETVNLAWDNEM-RVTEYLVVYTPTHEGGLEMQFRVPGDQTSTIIQELEPGVEYF 689
VTE+T + ++W + V+ + V Y + EG +P TS I +L PG +Y
Sbjct: 728 VTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYI 787
Query: 690 IRVFAILEN-KKSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPLDIAFETWEIIFRN 748
+ V+ I E+ ++S+ +S T AP + +TS+ V W + I++
Sbjct: 788 VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVY-- 845
Query: 749 MNKEDEGEITKSLRRPETSYRQT--GLAPGQEYEISLHIVKNNTRGPGL----KRVTTTR 802
+ EG T+ L PET+ T L PG +Y I+++ V+ N + + T R
Sbjct: 846 -SPSVEGSSTE-LNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPR 903
Query: 803 LD---APSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQYS 859
D +P ++ +VTD I W P + + G + ++PG+ L N ++
Sbjct: 904 SDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQ-RLPISRNTFA 962
Query: 860 -IGNLKPDTEYEVSLISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSITLEWRNGKA 918
+ L P Y + + S P TT LDAP NL+ V++TD+++ + W +A
Sbjct: 963 EVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRA 1022
Query: 919 AIDSYRIKYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKEDKESNPAT 978
I YR+ G + +V S +K L L+P +EY + + A+K ++ES AT
Sbjct: 1023 QITGYRLTVGLTRRGQPRQYNVGPS---VSKYPLRNLQPASEYTVSLVAIKGNQESPKAT 1079
Query: 979 INAATELDTPKDLQV--SETAETSLTLLWKTPLAKFDRYRLNYSLPTGQWVGVQLPRNTT 1036
T L + +E ET++ + W TP R+ + L G + PR T
Sbjct: 1080 -GVFTTLQPGSSIPPYNTEVTETTIVITW-TPAP-----RIGFKLGVRPSQGGEAPREVT 1132
Query: 1037 S----YVLRGLEPGQEY-NVLLTAEKGRHKSKPARVKASTEQAPELE-------NLTVTE 1084
S V+ GL PG EY + G+ + P K T +P + V
Sbjct: 1133 SDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLT 1192
Query: 1085 VGWD--------GLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKA 1136
V W+ G R+ T + + + +V A++ + PG
Sbjct: 1193 VSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPG------------ 1240
Query: 1137 ATPYTVSIYGVIQGYRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWTAPEGA--YEY 1194
Y VS+Y ++ + V ++ E P L ++ ++ ++ L WT + Y
Sbjct: 1241 -LEYNVSVY-TVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGY 1298
Query: 1195 FFIQVQEADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLTE 1254
V + + ++ V + + GL+ Y I++ + + P ++ T
Sbjct: 1299 RITVVAAGEGIPIFEDF-VDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTA 1357
Query: 1255 EVPDMGNLTVTEVSWDALRLNWTTPDGT-YDQFTIQVQEADQVEEAHNLTVPGSLRSMEI 1313
VP +L T + D +R+ W P F ++ E+ L++ S ++ +
Sbjct: 1358 -VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL 1416
Query: 1314 PGLRAGTPYTVTLHGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWDGLRLNWTAADNA 1373
L GT Y V++ H + PL T L + S++ + ++W A
Sbjct: 1417 TNLLPGTEYVVSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFSDITANSFTVHWIAPRAT 1475
Query: 1374 YEHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEA 1433
+ I+ + + +P S ++ + L T Y VSI + +P+L +
Sbjct: 1476 ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQ 1535
Query: 1434 STAKEPEIGNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTA 1493
ST + +L V TP S +SW A + I ++ E+ + G++ TA
Sbjct: 1536 STVSDVP-RDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1594
Query: 1494 HISGLPPSTDFIVYL-----SGLAPSIRTKTISATATTEALPLLENLTISDINPYGFTVS 1548
ISGL P D+ + + G +P+ +K IS TE + + ++D+ +V
Sbjct: 1595 TISGLKPGVDYTITVYAVTGRGDSPA-SSKPISINYRTE-IDKPSQMQVTDVQDNSISVK 1652
Query: 1549 WMASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFTQGHQT 1608
W+ S + + VT + T Q ++ + GL + Y V V ++
Sbjct: 1653 WLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGES 1712
Query: 1609 KPLRAEIVTEAEPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQSEPLEITL 1668
+PL VT + L +D D +++W + +G + + + L
Sbjct: 1713 QPLVQTAVTNID-RPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAP 1771
Query: 1669 LAPERTRDITGLREATEYEIELYGISKGRRSQTVSAIATTAMGSPKEVIFSDITENSATV 1728
E T ++ GLR +EY + + + SQ + +TA+ +P ++ F+ +T S +
Sbjct: 1772 DGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSA 1831
Query: 1729 SWRAPTAQVESFRITYVPITGGTPSM-VTVDGTKTQTRLVKLIPGVEYLVSIIAMKGFEE 1787
W P Q+ +R+ P P + + + + L+ +Y VS+ A+K
Sbjct: 1832 QWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLT 1891
Query: 1788 SEPVSGSFTTA--LDGPSGLVTANITDSEALARWQPAIATVDSYVI-SYTGEKVPEITRT 1844
S P G TT + P + T++ W+ T+ + + + I RT
Sbjct: 1892 SRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRT 1951
Query: 1845 VSGNTVEYALTDLEPATEYTLRIFAEKGPQKSSTITAKFTTDLDSPRDLTATEVQSETAL 1904
+ + Y +T L+P T+Y + ++ +SS + +T +D+P +L + L
Sbjct: 1952 IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLL 2011
Query: 1905 LTWRPPRASVTGYLLVYESVDGTVKEVI--VGPDTTSYSLADLSPSTHYTAKIQALNGPL 1962
++W+PPRA +TGY++ YE +EV+ P T ++ L P T YT + AL
Sbjct: 2012 VSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQ 2071
Query: 1963 RS 1964
+S
Sbjct: 2072 KS 2073
Score = 314 bits (805), Expect = 5e-85
Identities = 310/1276 (24%), Positives = 535/1276 (41%), Gaps = 96/1276 (7%)
Query: 767 SYRQTGLAPGQEYEISLHIVKN--------------NTRGPGLKRVTTTRLDAPSQI--- 809
SY GL PG YE L ++ +T P T S +
Sbjct: 665 SYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVAT 724
Query: 810 --EVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQYSIGNLKPDT 867
V ++T ++ +++W + G + Y + + + +DL +I +L P
Sbjct: 725 SESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGR 784
Query: 868 EYEVSL--ISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSITLEWRNGKAAIDSYRI 925
+Y V++ IS G+ S + TT DAP + D SI + W +A I YRI
Sbjct: 785 KYIVNVYQISEDGEQSLILSTSQ-TTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRI 843
Query: 926 KYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKEDKESNPATINAATE- 984
Y+P G E+++P++ + T L+ L+PG +Y I + AV+E++ES P I T
Sbjct: 844 VYSPSVEGSSTELNLPETANSVT---LSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
Query: 985 ------LDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNY---SLPTGQWVGVQLPRNT 1035
+ +P+DLQ E + +T++W P + YR++ +LP + + RNT
Sbjct: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
Query: 1036 TSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTE-QAPELENLTVTEVGWDGLRLNW 1094
+ V GL PG Y + A +SKP + +T+ AP NL + + W
Sbjct: 961 FAEVT-GLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPT--NLQFVNETDSTVLVRW 1017
Query: 1095 TAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVIQGYRTP 1154
T + + V + + R V S+ + L+ A+ YTVS+ + +P
Sbjct: 1018 TPPRAQITGYRLTVGLTRRGQP-RQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESP 1076
Query: 1155 VLSAEASTGETPNLGEVVVAEVGWDALKLNWT-APEGAYEYFFIQVQEADTVEAAQNLTV 1213
+ +T + + EV + + WT AP ++ + V+ + EA + +T
Sbjct: 1077 KATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFK---LGVRPSQGGEAPREVTS 1133
Query: 1214 PGGLRSTDLPGLKAATHYTITIR----GVTQDFS-----TTPLS--VEVLTEEVPDMGNL 1262
G S + GL Y TI+ G +D TPLS + E PD G L
Sbjct: 1134 DSG--SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVL 1191
Query: 1263 TVTEVSWDALRLNWTTPDGTYDQFTIQV---QEADQVEEAHNLTVPGSLRSMEIPGLRAG 1319
TV SW+ TTPD T + T Q+ + +EE V S L G
Sbjct: 1192 TV---SWERS----TTPDITGYRITTTPTNGQQGNSLEEV----VHADQSSCTFDNLSPG 1240
Query: 1320 TPYTVTLHGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVI 1379
Y V+++ + P++ ++ E +PQL DL+ ++ + L WT +++ I
Sbjct: 1241 LEYNVSVYTVKDDKESVPISDTIIPE-VPQLTDLSFVDITDSSIGLRWTPLNSS----TI 1295
Query: 1380 QVQEVNKVEAAQNLTL-----PGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEAS 1434
+ V A + + + S+ + GLE Y +S+ +I G + +
Sbjct: 1296 IGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQ 1355
Query: 1435 TAKEPEIGNLNVSDITPESFNLSWMATDGIFET-FTIEIIDSNRLLETVEYNISGAERTA 1493
TA P +L ++I P++ ++W I T F + + E +IS ++
Sbjct: 1356 TAVPPPT-DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAV 1414
Query: 1494 HISGLPPSTDFIVYLSGLAPSIRTKTISATATTEALPLLENLTISDINPYGFTVSWMASE 1553
++ L P T+++V +S + + + T L + SDI FTV W+A
Sbjct: 1415 VLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFSDITANSFTVHWIAPR 1473
Query: 1554 NAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFTQGHQTKPLRA 1613
+ + P+E + ++ + L L G Y V + G + PL
Sbjct: 1474 ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN-GREESPLLI 1532
Query: 1614 EIVTEAEPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQSEPLEITLLAPER 1673
+ +L V ATP +SW A + + +T S E T+ +
Sbjct: 1533 GQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKS 1592
Query: 1674 TRDITGLREATEYEIELYGISKGR-----RSQTVSAIATTAMGSPKEVIFSDITENSATV 1728
T I+GL+ +Y I +Y ++ GR S+ +S T + P ++ +D+ +NS +V
Sbjct: 1593 TATISGLKPGVDYTITVYAVT-GRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1651
Query: 1729 SWRAPTAQVESFRITYVPITGGTPSMVTVDGT-KTQTRLVKLIPGVEYLVSIIAMKGFEE 1787
W ++ V +R+T P G P+ G +T+ + L P VEY+VS+ A E
Sbjct: 1652 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1711
Query: 1788 SEPVSGSFTTALDGPSGLVTANITDSEALARWQPAIATVDSYVISYTGEK--VPEITRTV 1845
S+P+ + T +D P GL ++ W+ V Y ++Y+ + + E+
Sbjct: 1712 SQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAP 1771
Query: 1846 SGNTVEYALTDLEPATEYTLRIFAEKGPQKSSTITAKFTTDLDSPRDLTATEVQSETALL 1905
G L L P +EYT+ + A +S + +T + +P DL T+V +
Sbjct: 1772 DGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSA 1831
Query: 1906 TWRPPRASVTGYLL--VYESVDGTVKEVIVGPDTTSYSLADLSPSTHYTAKIQALNGPLR 1963
W PP +TGY + + G +KE+ + PD++S ++ L +T Y + AL L
Sbjct: 1832 QWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLT 1891
Query: 1964 SNMIQTIFTTIGLLYP 1979
S Q + TT+ + P
Sbjct: 1892 SRPAQGVVTTLENVSP 1907
Score = 224 bits (571), Expect = 7e-58
Identities = 238/1052 (22%), Positives = 418/1052 (39%), Gaps = 91/1052 (8%)
Query: 622 EVSPPKDLVVTEVTEETVNLAWD--NEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTII 679
EV DL ++T+ ++ L W N + Y + EG + V +
Sbjct: 1266 EVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTV 1325
Query: 680 QELEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPLDIAF 739
LEPG++Y I V ++ +S P + T +P P L+F +I ++ V W P
Sbjct: 1326 TGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSID 1385
Query: 740 ETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNNTRGPGLKRVT 799
T ++ + K +E S+ + + T L PG EY +S+ V L+
Sbjct: 1386 LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ 1445
Query: 800 TTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQYS 859
T LD+P+ I+ D+T + + W P A I G + + + G + N +
Sbjct: 1446 KTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSIT 1505
Query: 860 IGNLKPDTEYEVSLISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSITLEWRNGKAA 919
+ NL P TEY VS+++ G S +T D PR+L V+ T S+ + W
Sbjct: 1506 LTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT 1565
Query: 920 IDSYRIKYAPISGGDHA-EVDVPKSQQATTKTTLTGLRPGTEYGIGVSAV----KEDKES 974
+ YRI Y G E VP S+ + T++GL+PG +Y I V AV S
Sbjct: 1566 VRYYRITYGETGGNSPVQEFTVPGSK---STATISGLKPGVDYTITVYAVTGRGDSPASS 1622
Query: 975 NPATINAATELDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYSLPTGQWVGVQLPRN 1034
P +IN TE+D P +QV++ + S+++ W + YR+ + G P
Sbjct: 1623 KPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPG-----PTK 1677
Query: 1035 T-------TSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTEQAPELENLTVTEVGW 1087
T T + GL+P EY V + A+ +S+P V+ + + L T+V
Sbjct: 1678 TKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL-VQTAVTNIDRPKGLAFTDVDV 1736
Query: 1088 DGLRLNWTAADQAYEHFIIQVQEANKVEAARNL--TVPGSLRAVDIPGLKAATPYTVSIY 1145
D +++ W + + +V ++ + L G ++ GL+ + YTVS+
Sbjct: 1737 DSIKIAWESPQGQVSRY--RVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVV 1794
Query: 1146 GVIQGYRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEADTV 1205
+ + L ST P ++ +V +L WT P + ++V +
Sbjct: 1795 ALHDDMESQPLIGTQSTA-IPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKT 1853
Query: 1206 EAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLT-EEVPDMGNLTV 1264
+ + + S + GL AT Y +++ + ++ P V T E V V
Sbjct: 1854 GPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARV 1913
Query: 1265 TEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTV 1324
T+ + + ++W T T F + A+ + T+ +RS I GL+ GT Y +
Sbjct: 1914 TDATETTITISWRTKTETITGFQVDAVPANG-QTPIQRTIKPDVRSYTITGLQPGTDYKI 1972
Query: 1325 TLHGEVRGHSTRPLAVEVVTE-DLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQVQE 1383
L+ + P+ ++ T D P +L + L ++W ++I+ ++
Sbjct: 1973 YLYTLNDNARSSPVVIDASTAIDAP--SNLRFLATTPNSLLVSWQPPRARITGYIIKYEK 2030
Query: 1384 V-NKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEASTAKEPEIG 1442
+ PG A I GLE T Y +IY V++ + + EP IG
Sbjct: 2031 PGSPPREVVPRPRPGVTEAT-ITGLEPGTEY--TIY---------VIALKNNQKSEPLIG 2078
Query: 1443 NLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTAHISGLPPST 1502
TP + + +GI T + + + + G RT PP+T
Sbjct: 2079 RKKTVQKTPFVTHPGYDTGNGIQLPGTSG--QQPSVGQQMIFEEHGFRRTT-----PPTT 2131
Query: 1503 DFIV--YLSGLAPSIRTKTISATATTEALPLLENLTISDINPYGFTVSWMASENAFDSFL 1560
+ P++ + +S T T+SW ++ ++
Sbjct: 2132 ATPIRHRPRPYPPNVGQEALSQT----------------------TISWAPFQDT-SEYI 2168
Query: 1561 VTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFTQGHQTKPLRAEIVTEAE 1620
++ G +P +F + GT L GL G Y ++V + Q +R E+VT
Sbjct: 2169 ISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEAL-KDQQRHKVREEVVT--- 2224
Query: 1621 PEVDNLLVSDATPDGFRLSWTADEGVFDNFVL 1652
V ++ +G L+ D+ FD + +
Sbjct: 2225 -------VGNSVNEG--LNQPTDDSCFDPYTV 2247
Score = 208 bits (530), Expect = 4e-53
Identities = 186/811 (22%), Positives = 334/811 (41%), Gaps = 56/811 (6%)
Query: 617 GEDCSEVSPPKDLVVTEVTEETVNLAW-DNEMRVTEYLVVYTPTHEGGLEMQFRVPGDQT 675
G + + P + +++T + + W +T Y + + P H G + RVP +
Sbjct: 1443 GRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRN 1502
Query: 676 STIIQELEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPL 735
S + L PG EY + + A+ ++S + + +T P L+ + TS+ + WD
Sbjct: 1503 SITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP 1562
Query: 736 DIAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNNTRGPGL 795
+ + I + + ++ +++ +GL PG +Y I+++ V P
Sbjct: 1563 AVTVRYYRITYGETGGNSPVQ-EFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPAS 1621
Query: 796 KRVTT----TRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDL 851
+ + T +D PSQ++V DV D + + W + + G +T K+ PG T
Sbjct: 1622 SKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTA 1681
Query: 852 TEDENQYSIGNLKPDTEYEVSLISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSITL 911
D+ + +I L+P EY VS+ ++ S P +T T +D P+ L +SI +
Sbjct: 1682 GPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKI 1741
Query: 912 EWRNGKAAIDSYRIKYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKED 971
W + + + YR+ Y+ G H P ++ T + L GLRPG+EY + V A+ +D
Sbjct: 1742 AWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAE--LQGLRPGSEYTVSVVALHDD 1799
Query: 972 KESNPATINAATELDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYS--LPTGQWVGV 1029
ES P +T + P DL+ ++ TSL+ W P + YR+ + TG +
Sbjct: 1800 MESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEI 1859
Query: 1030 QLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPAR-VKASTEQAPELENLTVTEVGWD 1088
L +++S V+ GL +Y V + A K S+PA+ V + E VT+
Sbjct: 1860 NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATET 1919
Query: 1089 GLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVI 1148
+ ++W + F + AN + T+ +R+ I GL+ T Y + +Y +
Sbjct: 1920 TITISWRTKTETITGFQVDAVPANG-QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1978
Query: 1149 QGYRTPVLSAEASTG-ETP-NLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEADTVE 1206
R+ + +AST + P NL + ++L ++W P + I+ ++ +
Sbjct: 1979 DNARSSPVVIDASTAIDAPSNLRFLATTP---NSLLVSWQPPRARITGYIIKYEKPGSPP 2035
Query: 1207 AAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLTEEVPDMGNLTVTE 1266
G+ + GL+ T YTI + + + + PL T + VT
Sbjct: 2036 REVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPF----VTH 2091
Query: 1267 VSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTVTL 1326
+D N GT Q Q+ + E H G R TP T
Sbjct: 2092 PGYDT--GNGIQLPGTSGQQPSVGQQ--MIFEEH--------------GFRRTTPPTTAT 2133
Query: 1327 HGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQVQEVNK 1386
+R H RP P +G A+S+ ++W + E ++I V
Sbjct: 2134 --PIR-HRPRPYP--------PNVGQEALSQT-----TISWAPFQDTSE-YIISCHPVGT 2176
Query: 1387 VEAAQNLTLPGSLRAVDIPGLEAATPYRVSI 1417
E +PG+ + + GL Y + +
Sbjct: 2177 DEEPLQFRVPGTSTSATLTGLTRGATYNIIV 2207
Score = 189 bits (479), Expect = 3e-47
Identities = 144/609 (23%), Positives = 258/609 (42%), Gaps = 67/609 (11%)
Query: 621 SEVSPPKDLVVTEVTEETVNLAW-DNEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTII 679
+E+ P + VT+V + ++++ W + VT Y V TP + G DQT I
Sbjct: 1631 TEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTI 1690
Query: 680 QELEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPLDIAF 739
+ L+P VEY + V+A + +S P+ T + P+GL F + S+++ W+
Sbjct: 1691 EGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQV 1750
Query: 740 ETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNNTRGPGLKRVT 799
+ + + + ++ E+ + E + GL PG EY +S+ + ++ L
Sbjct: 1751 SRYRVTYSSP-EDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQ 1809
Query: 800 TTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQYS 859
+T + AP+ ++ VT T+ W P ++ G + K+ G I+L D +
Sbjct: 1810 STAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVV 1869
Query: 860 IGNLKPDTEYEVSLISRRGDMSSNPAKETFTT--GLDAPRNLRRVSQTDNSITLEWRNGK 917
+ L T+YEVS+ + + ++S PA+ TT + PR R T+ +IT+ WR
Sbjct: 1870 VSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT 1929
Query: 918 AAIDSYRIKYAPISGGDHAEVDVPKSQQATTKT-TLTGLRPGTEYGIGVSAVKEDKESNP 976
I +++ P +G + + ++ + ++ T+TGL+PGT+Y I + + ++ S+P
Sbjct: 1930 ETITGFQVDAVPANG----QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP 1985
Query: 977 ATINAATELDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYSLPTGQWVGVQLPR--- 1033
I+A+T +D P +L+ T SL + W+ P A+ Y + Y P G +PR
Sbjct: 1986 VVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKP-GSPPREVVPRPRP 2044
Query: 1034 NTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPA------------------------RVKA 1069
T + GLEPG EY + + A K KS+P ++
Sbjct: 2045 GVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYDTGNGIQLPG 2104
Query: 1070 STEQAPELENLTVTE--------------------------VGWDGLR---LNWTAADQA 1100
++ Q P + + E VG + L ++W A Q
Sbjct: 2105 TSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISW-APFQD 2163
Query: 1101 YEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVIQGYRTPVLSAEA 1160
+II E VPG+ + + GL Y + + + R V
Sbjct: 2164 TSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVV 2223
Query: 1161 STGETPNLG 1169
+ G + N G
Sbjct: 2224 TVGNSVNEG 2232
Score = 152 bits (385), Expect = 3e-36
Identities = 152/694 (21%), Positives = 275/694 (39%), Gaps = 47/694 (6%)
Query: 1365 LNWTAADNAY-EHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIR- 1422
+ W A ++ ++++ + N V + T+PG L + I GL+ Y + + +
Sbjct: 628 IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687
Query: 1423 GYR-------------TPVLSAEASTAKEP----EIGNLNVSDITPESFNLSWMATDGIF 1465
G++ TPV S + P + +V++IT SF +SW++
Sbjct: 688 GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747
Query: 1466 ETFTIEIIDSNRLLETVEYNISGAERTAHISGLPPSTDFIVYLSGLAPSIRTKTISATAT 1525
F +E S E ++ + +I L P +IV + ++ I +T+
Sbjct: 748 SGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQ 807
Query: 1526 TEALPLLENLTISDINPYGFTVSWMASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLE 1585
T A + T+ ++ V W + + + S + E L T +
Sbjct: 808 TTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEG-SSTELNLPETANSVT 866
Query: 1586 LRGLITGIGYEVMVSGFTQGHQTKPLRAEIVTEAEPEVD------NLLVSDATPDGFRLS 1639
L L G+ Y + + + ++ P+ + T P D +L + T +
Sbjct: 867 LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926
Query: 1640 WTADEGVFDNFVLKIRDTKKQSEPLEITLLAPERTRDITGLREATEYEIELYGISKGRRS 1699
WT E + + + E + ++ ++TGL Y +++ +S GR S
Sbjct: 927 WTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986
Query: 1700 QTVSAIATTAMGSPKEVIFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSMVTVDG 1759
+ ++A TT + +P + F + T+++ V W P AQ+ +R+T G P V
Sbjct: 987 KPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGP 1046
Query: 1760 TKTQTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTTALDGPS-GLVTANITDSEALAR 1818
+ ++ L L P EY VS++A+KG +ES +G FTT G S +T++ +
Sbjct: 1047 SVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVIT 1106
Query: 1819 WQPAIATVDSYVISYTGEKVPEITRTVSGNTVEYALTDLEPATEYTLRI-FAEKGPQKSS 1877
W PA + + + E R V+ ++ ++ L P EY I G ++ +
Sbjct: 1107 WTPAPRI--GFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDA 1164
Query: 1878 TITAKFTTDLDSPRDLTATEVQSETALLT--W-RPPRASVTGYLLVYESVD---GTVKEV 1931
I K T L P +L E +T +LT W R +TGY + + G E
Sbjct: 1165 PIVNKVVTPLSPPTNL-HLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEE 1223
Query: 1932 IVGPDTTSYSLADLSPSTHYTAKIQALNG-----PLRSNMIQTIFTTIGLLYPFPKDCSQ 1986
+V D +S + +LSP Y + + P+ +I + L + D S
Sbjct: 1224 VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSI 1283
Query: 1987 AM----LNGDTTSGL-YTIYLNGDKAEALEVFCD 2015
+ LN T G T+ G+ E F D
Sbjct: 1284 GLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVD 1317
>gi|47132549 fibronectin 1 isoform 6 preproprotein [Homo sapiens]
Length = 2176
Score = 364 bits (935), Expect = e-100
Identities = 341/1403 (24%), Positives = 585/1403 (41%), Gaps = 86/1403 (6%)
Query: 624 SPPKDLVVTEVTEETVN--LAWD--NEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTII 679
S P ++ +TE + + + W+ +++Y++ + P + G + +PG S I
Sbjct: 609 SGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTI 668
Query: 680 QELEPGVEYFIRVFAILE-------------NKKSIPVSARVATYLPAP------EGLKF 720
+ L+PGV Y ++ +I + S PV++ T P
Sbjct: 669 KGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESV 728
Query: 721 KSIKETSVEVEWDPLDIAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYE 780
I +S V W + + + + DE + L TS L PG++Y
Sbjct: 729 TEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYL-DLPSTATSVNIPDLLPGRKYI 787
Query: 781 ISLH-IVKNNTRGPGLKRVTTTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGI 839
++++ I ++ + L TT DAP V V DT+ ++ W +P A I G + Y
Sbjct: 788 VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYS- 846
Query: 840 KDVPGDRTTIDLTEDENQYSIGNLKPDTEYEVSLISRRGDMSSNPAK-ETFTTG------ 892
V G T ++L E N ++ +L+P +Y +++ + + S P + TTG
Sbjct: 847 PSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDT 906
Query: 893 LDAPRNLRRVSQTDNSITLEWRNGKAAIDSYRIKYAPIS-GGDHAEVDVPKSQQATTKTT 951
+ +PR+L+ V TD +T+ W ++A+ YR+ P++ G+H + +P S+ T
Sbjct: 907 VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQ-RLPISRN--TFAE 963
Query: 952 LTGLRPGTEYGIGVSAVKEDKESNPATINAATELDTPKDLQVSETAETSLTLLWKTPLAK 1011
+TGL PG Y V AV +ES P T T+LD P +LQ ++++ + W P A+
Sbjct: 964 VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQ 1023
Query: 1012 FDRYRLNYSLPT-GQWVGVQLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKAS 1070
YRL L GQ + + + Y LR L+P EY V L A KG +S A +
Sbjct: 1024 ITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFT 1083
Query: 1071 TEQAPELENLTVTEVGWDGLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVD 1130
T Q TEV + + WT A + F + V+ + EA R +T ++
Sbjct: 1084 TLQPGSSIPPYNTEVTETTIVITWTPAPRI--GFKLGVRPSQGGEAPREVTSDSG--SIV 1139
Query: 1131 IPGLKAATPYTVSIYGVIQGYR--TPVLSAEASTGETPNLGEVVVAEVGWDALKLNW--- 1185
+ GL Y +I + G P+++ + T +P + A L ++W
Sbjct: 1140 VSGLTPGVEYVYTIQVLRDGQERDAPIVN-KVVTPLSPPTNLHLEANPDTGVLTVSWERS 1198
Query: 1186 TAPE-GAYEYFFIQV--QEADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDF 1242
T P+ Y Q+ +++E V S L Y +++ V D
Sbjct: 1199 TTPDITGYRITTTPTNGQQGNSLEEV----VHADQSSCTFDNLSPGLEYNVSVYTVKDDK 1254
Query: 1243 STTPLSVEVLTEEVPDMGNLTVTEVSWDALRLNWTTPDGT-YDQFTIQVQEADQVEEAHN 1301
+ P+S + + VP +L T + D +R+ W P F ++ E+
Sbjct: 1255 ESVPIS-DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE 1313
Query: 1302 LTVPGSLRSMEIPGLRAGTPYTVTLHGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWD 1361
L++ S ++ + L GT Y V++ H + PL T L + S++ +
Sbjct: 1314 LSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFSDITAN 1372
Query: 1362 GLRLNWTAADNAYEHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVI 1421
++W A + I+ + + +P S ++ + L T Y VSI +
Sbjct: 1373 SFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN 1432
Query: 1422 RGYRTPVLSAEASTAKEPEIGNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLET 1481
+P+L + ST + +L V TP S +SW A + I ++
Sbjct: 1433 GREESPLLIGQQSTVSDVP-RDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPV 1491
Query: 1482 VEYNISGAERTAHISGLPPSTDFIVYL-----SGLAPSIRTKTISATATTEALPLLENLT 1536
E+ + G++ TA ISGL P D+ + + G +P+ +K IS TE + +
Sbjct: 1492 QEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPA-SSKPISINYRTE-IDKPSQMQ 1549
Query: 1537 ISDINPYGFTVSWMASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYE 1596
++D+ +V W+ S + + VT + T Q ++ + GL + Y
Sbjct: 1550 VTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYV 1609
Query: 1597 VMVSGFTQGHQTKPLRAEIVTEAEPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRD 1656
V V +++PL VT P +L + TP WT + +++
Sbjct: 1610 VSVYAQNPSGESQPLVQTAVTTI-PAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTP 1668
Query: 1657 TKKQSEPLEITLLAPERTRDITGLREATEYEIELYGISKGRRSQTVSAIATTA--MGSPK 1714
+K EI L + ++GL AT+YE+ +Y + S+ + TT + P+
Sbjct: 1669 KEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPR 1728
Query: 1715 EVIFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSMVTVDGTKTQTRLVKLIPGVE 1774
+D TE + T+SWR T + F++ VP G TP T+ + L PG +
Sbjct: 1729 RARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTD 1788
Query: 1775 YLVSIIAMKGFEESEPVSGSFTTALDGPSGLVTANITDSEALARWQPAIATVDSYVISY- 1833
Y + + + S PV +TA+D PS L T + L WQP A + Y+I Y
Sbjct: 1789 YKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYE 1848
Query: 1834 -TGEKVPEITRTVSGNTVEYALTDLEPATEYTLRIFAEKGPQKSSTITAKFTTDLDSPRD 1892
G E+ E +T LEP TEYT+ + A K QKS + R
Sbjct: 1849 KPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIG---------RK 1899
Query: 1893 LTATEVQSETALLTWRPPRASVTGYLLVYESVDGTVKEVI---VGPDTTSYSLADLSPST 1949
T E S+T ++W P + + Y++ V GT +E + V +TS +L L+
Sbjct: 1900 KTGQEALSQTT-ISWAPFQ-DTSEYIISCHPV-GTDEEPLQFRVPGTSTSATLTGLTRGA 1956
Query: 1950 HYTAKIQALNGPLRSNMIQTIFT 1972
Y ++AL R + + + T
Sbjct: 1957 TYNIIVEALKDQQRHKVREEVVT 1979
Score = 278 bits (710), Expect = 6e-74
Identities = 271/1105 (24%), Positives = 440/1105 (39%), Gaps = 52/1105 (4%)
Query: 623 VSPPKDLVVTEVTEETVNLAW-DNEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTIIQE 681
V P+DL EVT+ V + W E VT Y V P + G Q T +
Sbjct: 907 VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTG 966
Query: 682 LEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPLDIAFET 741
L PGV Y+ +VFA+ ++S P++A+ T L AP L+F + +++V V W P
Sbjct: 967 LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITG 1026
Query: 742 WEIIFRNMNKEDEGEITKSLRRPETS-YRQTGLAPGQEYEISLHIVKNNTRGPGLKRVTT 800
+ + + G+ + P S Y L P EY +SL +K N P V T
Sbjct: 1027 YRL---TVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFT 1083
Query: 801 TRLDAPSQIEV--KDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQY 858
T L S I +VT+TT +ITW P I G +L G++ G ++T D
Sbjct: 1084 T-LQPGSSIPPYNTEVTETTIVITW-TPAPRI-GFKL--GVRPSQGGEAPREVTSDSGSI 1138
Query: 859 SIGNLKPDTEYEVSL-ISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSI-TLEW-RN 915
+ L P EY ++ + R G P T L P NL + D + T+ W R+
Sbjct: 1139 VVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERS 1198
Query: 916 GKAAIDSYRIKYAPISG--GDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKEDKE 973
I YRI P +G G+ E V Q + T L PG EY + V VK+DKE
Sbjct: 1199 TTPDITGYRITTTPTNGQQGNSLEEVVHADQ---SSCTFDNLSPGLEYNVSVYTVKDDKE 1255
Query: 974 SNPATINAATELDTPKDLQVSETAETSLTLLWKTPLA-KFDRYRLNYSLPTGQ--WVGVQ 1030
S P + + P DL+ + ++ + W P + + + YS + +
Sbjct: 1256 SVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELS 1315
Query: 1031 LPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTEQAPELENLTVTEVGWDGL 1090
+ + + VL L PG EY V +++ +H+S P R + T + +++ +
Sbjct: 1316 ISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFSDITANSF 1374
Query: 1091 RLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVIQG 1150
++W A + I+ + R VP S ++ + L T Y VSI +
Sbjct: 1375 TVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR 1434
Query: 1151 YRTPVLSAEAST-GETPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEADTVEAAQ 1209
+P+L + ST + P EVV A +L ++W AP Y+ I E Q
Sbjct: 1435 EESPLLIGQQSTVSDVPRDLEVVAATP--TSLLISWDAPAVTVRYYRITYGETGGNSPVQ 1492
Query: 1210 NLTVPGGLRSTDLPGLKAATHYTITIRGVT----QDFSTTPLSVEVLTEEVPDMGNLTVT 1265
TVPG + + GLK YTIT+ VT S+ P+S+ T E+ + VT
Sbjct: 1493 EFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRT-EIDKPSQMQVT 1551
Query: 1266 EVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTVT 1325
+V +++ + W + + + T M I GL+ Y V+
Sbjct: 1552 DVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVS 1611
Query: 1326 LHGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQVQEVN 1385
++ + ++PL VT +P DL ++V L WT + + ++V
Sbjct: 1612 VYAQNPSGESQPLVQTAVT-TIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKE 1670
Query: 1386 KVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRT-PVLSAEASTAKEPEIGNL 1444
K + + L +V + GL AT Y VS+Y + + P +
Sbjct: 1671 KTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRA 1730
Query: 1445 NVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTAHISGLPPSTDF 1504
V+D T + +SW F ++ + +N ++ I R+ I+GL P TD+
Sbjct: 1731 RVTDATETTITISWRTKTETITGFQVDAVPANG-QTPIQRTIKPDVRSYTITGLQPGTDY 1789
Query: 1505 IVYLSGLAPSIRTKTISATATTEALPLLENLTISDINPYGFTVSWMASENAFDSFLVTVV 1564
+YL L + R+ + A+T A+ NL P VSW +++
Sbjct: 1790 KIYLYTLNDNARSSPVVIDAST-AIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYE 1848
Query: 1565 DSGKLLDPQEFTLSGTQRKLE--LRGLITGIGYEVMVSGFTQGHQTKPLRAEIVTEAEPE 1622
G P+E E + GL G Y + V +++PL T E
Sbjct: 1849 KPGS--PPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQE-- 1904
Query: 1623 VDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQSEPLEITLLAPERTRDITGLRE 1682
+S T +SW + +++ EPL+ + + +TGL
Sbjct: 1905 ----ALSQTT-----ISWAPFQDT-SEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTR 1954
Query: 1683 ATEYEIELYGISKGRRSQTVSAIAT 1707
Y I + + +R + + T
Sbjct: 1955 GATYNIIVEALKDQQRHKVREEVVT 1979
Score = 229 bits (584), Expect = 2e-59
Identities = 252/1125 (22%), Positives = 465/1125 (41%), Gaps = 74/1125 (6%)
Query: 907 NSITLEWRNGKAA-IDSYRIKYAPISG-GDHAEVDVPKSQQATTKTTLTGLRPGTEYGIG 964
NS ++W + + I Y +++ P + G E +P + T + GL+PG Y
Sbjct: 624 NSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYT---IKGLKPGVVYEGQ 680
Query: 965 VSAVKE-------------DKESNPATINAATELDTP------KDLQVSETAETSLTLLW 1005
+ ++++ S P T N T TP V+E +S + W
Sbjct: 681 LISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSW 740
Query: 1006 KTPLAKFDRYRLNYSLPT--GQWVGVQLPRNTTSYVLRGLEPGQEY--NVLLTAEKGRHK 1061
+ +R+ Y L + + LP TS + L PG++Y NV +E G
Sbjct: 741 VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQS 800
Query: 1062 SKPARVKASTEQAPELENLTVTEVGWDGLRLNWTAADQAYEHFIIQVQEANKVEAARNLT 1121
+ + + AP + TV +V + + W+ + I V + ++ L
Sbjct: 801 LILSTSQTTAPDAPP--DPTVDQVDDTSIVVRWSRPQAPITGYRI-VYSPSVEGSSTELN 857
Query: 1122 VPGSLRAVDIPGLKAATPYTVSIYGVIQGYR-TPVLSAEASTGE-----TPNLGEVVVAE 1175
+P + +V + L+ Y ++IY V + TPV+ + +TG P+ ++ E
Sbjct: 858 LPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVE 917
Query: 1176 VGWDALKLNWTAPEGAYEYFFIQVQEADTV-EAAQNLTVPGGLRST--DLPGLKAATHYT 1232
V + + WT PE A + + V + E Q L + R+T ++ GL Y
Sbjct: 918 VTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPIS---RNTFAEVTGLSPGVTYY 974
Query: 1233 ITIRGVTQDFSTTPLSVEVLTE-EVPDMGNLTVTEVSWDALRLNWTTPDGTYDQFTIQVQ 1291
+ V+ + PL+ + T+ + P NL + + + WT P + + V
Sbjct: 975 FKVFAVSHGRESKPLTAQQTTKLDAPT--NLQFVNETDSTVLVRWTPPRAQITGYRLTVG 1032
Query: 1292 EADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTVTLHGEVRGHSTRPLAVEVVTEDLPQLG 1351
+ + V S+ + L+ + YTV+L ++G+ P A V T P
Sbjct: 1033 LTRR-GQPRQYNVGPSVSKYPLRNLQPASEYTVSLVA-IKGNQESPKATGVFTTLQPGSS 1090
Query: 1352 DLAVS-EVGWDGLRLNWTAADNAYEHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAA 1410
+ EV + + WT A F + V+ EA + +T ++ + GL
Sbjct: 1091 IPPYNTEVTETTIVITWTPAPRI--GFKLGVRPSQGGEAPREVTSDSG--SIVVSGLTPG 1146
Query: 1411 TPYRVSIYGVIRGYR--TPVLSAEASTAKEPEIGNLNVSDITPES--FNLSW-MATDGIF 1465
Y +I + G P+++ + P NL++ + P++ +SW +T
Sbjct: 1147 VEYVYTIQVLRDGQERDAPIVNKVVTPLSPPT--NLHL-EANPDTGVLTVSWERSTTPDI 1203
Query: 1466 ETFTIEIIDSN-RLLETVEYNISGAERTAHISGLPPSTDFIVYLSGLAPSIRTKTISATA 1524
+ I +N + ++E + + + L P ++ V + + + IS T
Sbjct: 1204 TGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTI 1263
Query: 1525 TTEALPLLENLTISDINPYGFTVSWMASENA-FDSFLVTVVDSGKLLDPQEFTLSGTQRK 1583
A+P +L ++I P V+W + +FLV D E ++S +
Sbjct: 1264 IP-AVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNA 1322
Query: 1584 LELRGLITGIGYEVMVSGFTQGHQTKPLRAEIVTEAEPEVDNLLVSDATPDGFRLSWTAD 1643
+ L L+ G Y V VS + H++ PLR T + + SD T + F + W A
Sbjct: 1323 VVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPT-GIDFSDITANSFTVHWIAP 1381
Query: 1644 EGVFDNFVLKIRDTKKQSEPLEITLLAPERTRDITGLREATEYEIELYGISKGRRSQTVS 1703
+ ++ P E + + +T L TEY + + ++ S +
Sbjct: 1382 RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLI 1441
Query: 1704 AIATTAMGSPKEVIFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSM-VTVDGTKT 1762
+T P+++ T S +SW AP V +RITY G +P TV G+K+
Sbjct: 1442 GQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKS 1501
Query: 1763 QTRLVKLIPGVEYLVSIIAMKGFEES----EPVSGSFTTALDGPSGLVTANITDSEALAR 1818
+ L PGV+Y +++ A+ G +S +P+S ++ T +D PS + ++ D+ +
Sbjct: 1502 TATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVK 1561
Query: 1819 WQPAIATVDSYVISYTGEKVPEITRTVSG--NTVEYALTDLEPATEYTLRIFAEKGPQKS 1876
W P+ + V Y ++ T + P T+T + + E + L+P EY + ++A+ +S
Sbjct: 1562 WLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGES 1621
Query: 1877 STITAKFTTDLDSPRDLTATEVQSETALLTWRPPRASVTGYLL--VYESVDGTVKEVIVG 1934
+ T + +P DL T+V + W PP +TGY + + G +KE+ +
Sbjct: 1622 QPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLA 1681
Query: 1935 PDTTSYSLADLSPSTHYTAKIQALNGPLRSNMIQTIFTTIGLLYP 1979
PD++S ++ L +T Y + AL L S Q + TT+ + P
Sbjct: 1682 PDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSP 1726
Score = 207 bits (526), Expect = 1e-52
Identities = 145/564 (25%), Positives = 249/564 (44%), Gaps = 29/564 (5%)
Query: 617 GEDCSEVSPPKDLVVTEVTEETVNLAWDNE-MRVTEYLVVYTPTHEGGLEMQFRVPGDQT 675
G+ + P+DL V T ++ ++WD + V Y + Y T +F VPG ++
Sbjct: 1442 GQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKS 1501
Query: 676 STIIQELEPGVEYFIRVFAILEN----KKSIPVSARVATYLPAPEGLKFKSIKETSVEVE 731
+ I L+PGV+Y I V+A+ S P+S T + P ++ +++ S+ V+
Sbjct: 1502 TATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVK 1561
Query: 732 WDPLDIAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNNTR 791
W P + + N + TK+ +T GL P EY +S++ +
Sbjct: 1562 WLPSSSPVTGYRVTTTPKNGPGPTK-TKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1620
Query: 792 GPGLKRVTTTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDL 851
L + T + AP+ ++ VT T+ W P ++ G + K+ G I+L
Sbjct: 1621 SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL 1680
Query: 852 TEDENQYSIGNLKPDTEYEVSLISRRGDMSSNPAKETFTT--GLDAPRNLRRVSQTDNSI 909
D + + L T+YEVS+ + + ++S PA+ TT + PR R T+ +I
Sbjct: 1681 APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI 1740
Query: 910 TLEWRNGKAAIDSYRIKYAPISGGDHAEVDVPKSQQATTKT-TLTGLRPGTEYGIGVSAV 968
T+ WR I +++ P +G + + ++ + ++ T+TGL+PGT+Y I + +
Sbjct: 1741 TISWRTKTETITGFQVDAVPANG----QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTL 1796
Query: 969 KEDKESNPATINAATELDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYSLPTGQWVG 1028
++ S+P I+A+T +D P +L+ T SL + W+ P A+ Y + Y P G
Sbjct: 1797 NDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKP-GSPPR 1855
Query: 1029 VQLPR---NTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTEQAPELENLTVTEV 1085
+PR T + GLEPG EY + + A K KS+P + T Q E L+ T +
Sbjct: 1856 EVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQ----EALSQTTI 1911
Query: 1086 GWDGLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIY 1145
W A Q +II E VPG+ + + GL Y + +
Sbjct: 1912 SW--------APFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVE 1963
Query: 1146 GVIQGYRTPVLSAEASTGETPNLG 1169
+ R V + G + N G
Sbjct: 1964 ALKDQQRHKVREEVVTVGNSVNEG 1987
Score = 153 bits (386), Expect = 2e-36
Identities = 147/662 (22%), Positives = 264/662 (39%), Gaps = 40/662 (6%)
Query: 1365 LNWTAADNAY-EHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIR- 1422
+ W A ++ ++++ + N V + T+PG L + I GL+ Y + + +
Sbjct: 628 IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687
Query: 1423 GYR-------------TPVLSAEASTAKEP----EIGNLNVSDITPESFNLSWMATDGIF 1465
G++ TPV S + P + +V++IT SF +SW++
Sbjct: 688 GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747
Query: 1466 ETFTIEIIDSNRLLETVEYNISGAERTAHISGLPPSTDFIVYLSGLAPSIRTKTISATAT 1525
F +E S E ++ + +I L P +IV + ++ I +T+
Sbjct: 748 SGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQ 807
Query: 1526 TEALPLLENLTISDINPYGFTVSWMASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLE 1585
T A + T+ ++ V W + + + S + E L T +
Sbjct: 808 TTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEG-SSTELNLPETANSVT 866
Query: 1586 LRGLITGIGYEVMVSGFTQGHQTKPLRAEIVTEAEPEVD------NLLVSDATPDGFRLS 1639
L L G+ Y + + + ++ P+ + T P D +L + T +
Sbjct: 867 LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926
Query: 1640 WTADEGVFDNFVLKIRDTKKQSEPLEITLLAPERTRDITGLREATEYEIELYGISKGRRS 1699
WT E + + + E + ++ ++TGL Y +++ +S GR S
Sbjct: 927 WTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986
Query: 1700 QTVSAIATTAMGSPKEVIFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSMVTVDG 1759
+ ++A TT + +P + F + T+++ V W P AQ+ +R+T G P V
Sbjct: 987 KPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGP 1046
Query: 1760 TKTQTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTTALDGPS-GLVTANITDSEALAR 1818
+ ++ L L P EY VS++A+KG +ES +G FTT G S +T++ +
Sbjct: 1047 SVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVIT 1106
Query: 1819 WQPAIATVDSYVISYTGEKVPEITRTVSGNTVEYALTDLEPATEYTLRI-FAEKGPQKSS 1877
W PA + + + E R V+ ++ ++ L P EY I G ++ +
Sbjct: 1107 WTPAPRI--GFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDA 1164
Query: 1878 TITAKFTTDLDSPRDLTATEVQSETALLT--W-RPPRASVTGYLLVYESVD---GTVKEV 1931
I K T L P +L E +T +LT W R +TGY + + G E
Sbjct: 1165 PIVNKVVTPLSPPTNL-HLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEE 1223
Query: 1932 IVGPDTTSYSLADLSPSTHYTAKIQALNGPLRSNMIQTIFTTIGLLYPFPKDCSQAMLNG 1991
+V D +S + +LSP Y + + S I TI P P D +
Sbjct: 1224 VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKES---VPISDTIIPAVPPPTDLRFTNIGP 1280
Query: 1992 DT 1993
DT
Sbjct: 1281 DT 1282
>gi|16933542 fibronectin 1 isoform 3 preproprotein [Homo sapiens]
Length = 2355
Score = 360 bits (925), Expect = 6e-99
Identities = 325/1394 (23%), Positives = 584/1394 (41%), Gaps = 73/1394 (5%)
Query: 624 SPPKDLVVTEVTEETVN--LAWD--NEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTII 679
S P ++ +TE + + + W+ +++Y++ + P + G + +PG S I
Sbjct: 609 SGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTI 668
Query: 680 QELEPGVEYFIRVFAILE-------------NKKSIPVSARVATYLPAP------EGLKF 720
+ L+PGV Y ++ +I + S PV++ T P
Sbjct: 669 KGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESV 728
Query: 721 KSIKETSVEVEWDPLDIAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYE 780
I +S V W + + + + DE + L TS L PG++Y
Sbjct: 729 TEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYL-DLPSTATSVNIPDLLPGRKYI 787
Query: 781 ISLH-IVKNNTRGPGLKRVTTTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGI 839
++++ I ++ + L TT DAP V V DT+ ++ W +P A I G + Y
Sbjct: 788 VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYS- 846
Query: 840 KDVPGDRTTIDLTEDENQYSIGNLKPDTEYEVSLISRRGDMSSNPAK-ETFTTG------ 892
V G T ++L E N ++ +L+P +Y +++ + + S P + TTG
Sbjct: 847 PSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDT 906
Query: 893 LDAPRNLRRVSQTDNSITLEWRNGKAAIDSYRIKYAPIS-GGDHAEVDVPKSQQATTKTT 951
+ +PR+L+ V TD +T+ W ++A+ YR+ P++ G+H + +P S+ T
Sbjct: 907 VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQ-RLPISRN--TFAE 963
Query: 952 LTGLRPGTEYGIGVSAVKEDKESNPATINAATELDTPKDLQVSETAETSLTLLWKTPLAK 1011
+TGL PG Y V AV +ES P T T+LD P +LQ ++++ + W P A+
Sbjct: 964 VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQ 1023
Query: 1012 FDRYRLNYSLPT-GQWVGVQLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKAS 1070
YRL L GQ + + + Y LR L+P EY V L A KG +S A +
Sbjct: 1024 ITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFT 1083
Query: 1071 TEQAPELENLTVTEVGWDGLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVD 1130
T Q TEV + + WT A + F + V+ + EA R +T ++
Sbjct: 1084 TLQPGSSIPPYNTEVTETTIVITWTPAPRI--GFKLGVRPSQGGEAPREVTSDSG--SIV 1139
Query: 1131 IPGLKAATPYTVSIYGVIQGYR--TPVLSAEASTGETPNLGEVVVAEVGWDALKLNW--- 1185
+ GL Y +I + G P+++ + T +P + A L ++W
Sbjct: 1140 VSGLTPGVEYVYTIQVLRDGQERDAPIVN-KVVTPLSPPTNLHLEANPDTGVLTVSWERS 1198
Query: 1186 TAPE-GAYEYFFIQV--QEADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDF 1242
T P+ Y Q+ +++E V S L Y +++ V D
Sbjct: 1199 TTPDITGYRITTTPTNGQQGNSLEEV----VHADQSSCTFDNLSPGLEYNVSVYTVKDDK 1254
Query: 1243 STTPLSVEVLTEEVPDMGNLTVTEVSWDALRLNWTTPDGT-YDQFTIQVQEADQVEEAHN 1301
+ P+S + + VP +L T + D +R+ W P F ++ E+
Sbjct: 1255 ESVPIS-DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE 1313
Query: 1302 LTVPGSLRSMEIPGLRAGTPYTVTLHGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWD 1361
L++ S ++ + L GT Y V++ H + PL T L + S++ +
Sbjct: 1314 LSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFSDITAN 1372
Query: 1362 GLRLNWTAADNAYEHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVI 1421
++W A + I+ + + +P S ++ + L T Y VSI +
Sbjct: 1373 SFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN 1432
Query: 1422 RGYRTPVLSAEASTAKEPEIGNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLET 1481
+P+L + ST + +L V TP S +SW A + I ++
Sbjct: 1433 GREESPLLIGQQSTVSDVP-RDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPV 1491
Query: 1482 VEYNISGAERTAHISGLPPSTDFIVYL-----SGLAPSIRTKTISATATTEALPLLENLT 1536
E+ + G++ TA ISGL P D+ + + G +P+ +K IS TE + +
Sbjct: 1492 QEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPA-SSKPISINYRTE-IDKPSQMQ 1549
Query: 1537 ISDINPYGFTVSWMASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYE 1596
++D+ +V W+ S + + VT + T Q ++ + GL + Y
Sbjct: 1550 VTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYV 1609
Query: 1597 VMVSGFTQGHQTKPLRAEIVTEAEPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRD 1656
V V +++PL VT + L +D D +++W + +G + +
Sbjct: 1610 VSVYAQNPSGESQPLVQTAVTNID-RPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSS 1668
Query: 1657 TKKQSEPLEITLLAPERTRDITGLREATEYEIELYGISKGRRSQTVSAIATTAMGSPKEV 1716
+ L E T ++ GLR +EY + + + SQ + +TA+ +P ++
Sbjct: 1669 PEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDL 1728
Query: 1717 IFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSM-VTVDGTKTQTRLVKLIPGVEY 1775
F+ +T S + W P Q+ +R+ P P + + + + L+ +Y
Sbjct: 1729 KFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKY 1788
Query: 1776 LVSIIAMKGFEESEPVSGSFTTA--LDGPSGLVTANITDSEALARWQPAIATVDSYVI-S 1832
VS+ A+K S P G TT + P + T++ W+ T+ + + +
Sbjct: 1789 EVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDA 1848
Query: 1833 YTGEKVPEITRTVSGNTVEYALTDLEPATEYTLRIFAEKGPQKSSTITAKFTTDLDSPRD 1892
I RT+ + Y +T L+P T+Y + ++ +SS + +T +D+P +
Sbjct: 1849 VPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSN 1908
Query: 1893 LTATEVQSETALLTWRPPRASVTGYLLVYESVDGTVKEVI--VGPDTTSYSLADLSPSTH 1950
L + L++W+PPRA +TGY++ YE +EV+ P T ++ L P T
Sbjct: 1909 LRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTE 1968
Query: 1951 YTAKIQALNGPLRS 1964
YT + AL +S
Sbjct: 1969 YTIYVIALKNNQKS 1982
Score = 342 bits (876), Expect = 3e-93
Identities = 309/1300 (23%), Positives = 527/1300 (40%), Gaps = 79/1300 (6%)
Query: 631 VTEVTEETVNLAWDNEM-RVTEYLVVYTPTHEGGLEMQFRVPGDQTSTIIQELEPGVEYF 689
VTE+T + ++W + V+ + V Y + EG +P TS I +L PG +Y
Sbjct: 728 VTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYI 787
Query: 690 IRVFAILEN-KKSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPLDIAFETWEIIFRN 748
+ V+ I E+ ++S+ +S T AP + +TS+ V W + I++
Sbjct: 788 VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVY-- 845
Query: 749 MNKEDEGEITKSLRRPETSYRQT--GLAPGQEYEISLHIVKNNTRGPGL----KRVTTTR 802
+ EG T+ L PET+ T L PG +Y I+++ V+ N + + T R
Sbjct: 846 -SPSVEGSSTE-LNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPR 903
Query: 803 LD---APSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQYS 859
D +P ++ +VTD I W P + + G + ++PG+ L N ++
Sbjct: 904 SDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQ-RLPISRNTFA 962
Query: 860 -IGNLKPDTEYEVSLISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSITLEWRNGKA 918
+ L P Y + + S P TT LDAP NL+ V++TD+++ + W +A
Sbjct: 963 EVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRA 1022
Query: 919 AIDSYRIKYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKEDKESNPAT 978
I YR+ G + +V S +K L L+P +EY + + A+K ++ES AT
Sbjct: 1023 QITGYRLTVGLTRRGQPRQYNVGPS---VSKYPLRNLQPASEYTVSLVAIKGNQESPKAT 1079
Query: 979 INAATELDTPKDLQV--SETAETSLTLLWKTPLAKFDRYRLNYSLPTGQWVGVQLPRNTT 1036
T L + +E ET++ + W TP R+ + L G + PR T
Sbjct: 1080 -GVFTTLQPGSSIPPYNTEVTETTIVITW-TPAP-----RIGFKLGVRPSQGGEAPREVT 1132
Query: 1037 S----YVLRGLEPGQEY-NVLLTAEKGRHKSKPARVKASTEQAPELE-------NLTVTE 1084
S V+ GL PG EY + G+ + P K T +P + V
Sbjct: 1133 SDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLT 1192
Query: 1085 VGWD--------GLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKA 1136
V W+ G R+ T + + + +V A++ + PG
Sbjct: 1193 VSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPG------------ 1240
Query: 1137 ATPYTVSIYGVIQGYRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWTAPEGA-YEYF 1195
Y VS+Y ++ + V ++ P ++ +G D +++ W P F
Sbjct: 1241 -LEYNVSVY-TVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNF 1298
Query: 1196 FIQVQEADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLTEE 1255
++ E L++ + L L T Y +++ V + +TPL T
Sbjct: 1299 LVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL 1358
Query: 1256 VPDMGNLTVTEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPG 1315
G + ++++ ++ ++W P T + I+ VP S S+ +
Sbjct: 1359 DSPTG-IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1417
Query: 1316 LRAGTPYTVTLHGEVRGHSTRPLAV--EVVTEDLPQLGDLAVSEVGWDGLRLNWTAADNA 1373
L GT Y V++ + G PL + + D+P+ DL V L ++W A
Sbjct: 1418 LTPGTEYVVSIVA-LNGREESPLLIGQQSTVSDVPR--DLEVVAATPTSLLISWDAPAVT 1474
Query: 1374 YEHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEA 1433
++ I E Q T+PGS I GL+ Y +++Y V +P S
Sbjct: 1475 VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPI 1534
Query: 1434 STAKEPEI---GNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAE 1490
S EI + V+D+ S ++ W+ + + + N T +
Sbjct: 1535 SINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1594
Query: 1491 RTAHISGLPPSTDFIVYLSGLAPSIRTKTISATATTEALPLLENLTISDINPYGFTVSWM 1550
I GL P+ +++V + PS ++ + TA T + + L +D++ ++W
Sbjct: 1595 TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTN-IDRPKGLAFTDVDVDSIKIAWE 1653
Query: 1551 ASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFTQGHQTKP 1610
+ + + VT + G + EL+GL G Y V V +++P
Sbjct: 1654 SPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQP 1713
Query: 1611 LRAEIVTEAEPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQSEPLEITLLA 1670
L T A P +L + TP WT + +++ +K EI L
Sbjct: 1714 LIGTQST-AIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAP 1772
Query: 1671 PERTRDITGLREATEYEIELYGISKGRRSQTVSAIATTA--MGSPKEVIFSDITENSATV 1728
+ ++GL AT+YE+ +Y + S+ + TT + P+ +D TE + T+
Sbjct: 1773 DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITI 1832
Query: 1729 SWRAPTAQVESFRITYVPITGGTPSMVTVDGTKTQTRLVKLIPGVEYLVSIIAMKGFEES 1788
SWR T + F++ VP G TP T+ + L PG +Y + + + S
Sbjct: 1833 SWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARS 1892
Query: 1789 EPVSGSFTTALDGPSGLVTANITDSEALARWQPAIATVDSYVISY--TGEKVPEITRTVS 1846
PV +TA+D PS L T + L WQP A + Y+I Y G E+
Sbjct: 1893 SPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPR 1952
Query: 1847 GNTVEYALTDLEPATEYTLRIFAEKGPQKSSTITAKFTTD 1886
E +T LEP TEYT+ + A K QKS + + TD
Sbjct: 1953 PGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTD 1992
Score = 313 bits (803), Expect = 9e-85
Identities = 308/1264 (24%), Positives = 532/1264 (42%), Gaps = 96/1264 (7%)
Query: 767 SYRQTGLAPGQEYEISLHIVKN--------------NTRGPGLKRVTTTRLDAPSQI--- 809
SY GL PG YE L ++ +T P T S +
Sbjct: 665 SYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVAT 724
Query: 810 --EVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQYSIGNLKPDT 867
V ++T ++ +++W + G + Y + + + +DL +I +L P
Sbjct: 725 SESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGR 784
Query: 868 EYEVSL--ISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSITLEWRNGKAAIDSYRI 925
+Y V++ IS G+ S + TT DAP + D SI + W +A I YRI
Sbjct: 785 KYIVNVYQISEDGEQSLILSTSQ-TTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRI 843
Query: 926 KYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKEDKESNPATINAATE- 984
Y+P G E+++P++ + T L+ L+PG +Y I + AV+E++ES P I T
Sbjct: 844 VYSPSVEGSSTELNLPETANSVT---LSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
Query: 985 ------LDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNY---SLPTGQWVGVQLPRNT 1035
+ +P+DLQ E + +T++W P + YR++ +LP + + RNT
Sbjct: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
Query: 1036 TSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTE-QAPELENLTVTEVGWDGLRLNW 1094
+ V GL PG Y + A +SKP + +T+ AP NL + + W
Sbjct: 961 FAEVT-GLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPT--NLQFVNETDSTVLVRW 1017
Query: 1095 TAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVIQGYRTP 1154
T + + V + + R V S+ + L+ A+ YTVS+ + +P
Sbjct: 1018 TPPRAQITGYRLTVGLTRRGQP-RQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESP 1076
Query: 1155 VLSAEASTGETPNLGEVVVAEVGWDALKLNWT-APEGAYEYFFIQVQEADTVEAAQNLTV 1213
+ +T + + EV + + WT AP ++ + V+ + EA + +T
Sbjct: 1077 KATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFK---LGVRPSQGGEAPREVTS 1133
Query: 1214 PGGLRSTDLPGLKAATHYTITIR----GVTQDFS-----TTPLS--VEVLTEEVPDMGNL 1262
G S + GL Y TI+ G +D TPLS + E PD G L
Sbjct: 1134 DSG--SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVL 1191
Query: 1263 TVTEVSWDALRLNWTTPDGTYDQFTIQV---QEADQVEEAHNLTVPGSLRSMEIPGLRAG 1319
TV SW+ TTPD T + T Q+ + +EE V S L G
Sbjct: 1192 TV---SWERS----TTPDITGYRITTTPTNGQQGNSLEEV----VHADQSSCTFDNLSPG 1240
Query: 1320 TPYTVTLHGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWDGLRLNWTAADNA-YEHFV 1378
Y V+++ + P++ + + +P DL + +G D +R+ W + +F+
Sbjct: 1241 LEYNVSVYTVKDDKESVPIS-DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFL 1299
Query: 1379 IQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEASTAKE 1438
++ V E L++ S AV + L T Y VS+ V + + L T +
Sbjct: 1300 VRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD 1359
Query: 1439 PEIGNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTAHISGL 1498
G ++ SDIT SF + W+A + I + E + + + ++ L
Sbjct: 1360 SPTG-IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNL 1418
Query: 1499 PPSTDFIVYLSGLAPSIRTKT-ISATATTEALPLLENLTISDINPYGFTVSWMASENAFD 1557
P T+++V + L + I +T +P +L + P +SW A
Sbjct: 1419 TPGTEYVVSIVALNGREESPLLIGQQSTVSDVP--RDLEVVAATPTSLLISWDAPAVTVR 1476
Query: 1558 SFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFT----QGHQTKPLRA 1613
+ +T ++G QEFT+ G++ + GL G+ Y + V T +KP+
Sbjct: 1477 YYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISI 1536
Query: 1614 EIVTEAEPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQSE-PLEITLLAPE 1672
TE + + + V+D + + W + ++ T K P + P+
Sbjct: 1537 NYRTEID-KPSQMQVTDVQDNSISVKWLPSSSPVTGY--RVTTTPKNGPGPTKTKTAGPD 1593
Query: 1673 RTR-DITGLREATEYEIELYGISKGRRSQTVSAIATTAMGSPKEVIFSDITENSATVSWR 1731
+T I GL+ EY + +Y + SQ + A T + PK + F+D+ +S ++W
Sbjct: 1594 QTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWE 1653
Query: 1732 APTAQVESFRITYVPITGGTPSMVTV-DGTKTQTRLVKLIPGVEYLVSIIAMKGFEESEP 1790
+P QV +R+TY G + DG + L L PG EY VS++A+ ES+P
Sbjct: 1654 SPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQP 1713
Query: 1791 VSGSFTTALDGPSGLVTANITDSEALARWQPAIATVDSYVISYTGEK----VPEITRTVS 1846
+ G+ +TA+ P+ L +T + A+W P + Y + T ++ + EI
Sbjct: 1714 LIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPD 1773
Query: 1847 GNTVEYALTDLEPATEYTLRIFAEKGPQKSSTITAKFTT--DLDSPRDLTATEVQSETAL 1904
++V ++ L AT+Y + ++A K S TT ++ PR T+ T
Sbjct: 1774 SSSV--VVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTIT 1831
Query: 1905 LTWRPPRASVTGYLLVYESVDG-TVKEVIVGPDTTSYSLADLSPSTHYTAKIQALNGPLR 1963
++WR ++TG+ + +G T + + PD SY++ L P T Y + LN R
Sbjct: 1832 ISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNAR 1891
Query: 1964 SNMI 1967
S+ +
Sbjct: 1892 SSPV 1895
Score = 277 bits (708), Expect = 9e-74
Identities = 270/1107 (24%), Positives = 446/1107 (40%), Gaps = 59/1107 (5%)
Query: 623 VSPPKDLVVTEVTEETVNLAW-DNEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTIIQE 681
V P+DL EVT+ V + W E VT Y V P + G Q T +
Sbjct: 907 VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTG 966
Query: 682 LEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPLDIAFET 741
L PGV Y+ +VFA+ ++S P++A+ T L AP L+F + +++V V W P
Sbjct: 967 LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITG 1026
Query: 742 WEIIFRNMNKEDEGEITKSLRRPETS-YRQTGLAPGQEYEISLHIVKNNTRGPGLKRVTT 800
+ + + G+ + P S Y L P EY +SL +K N P V T
Sbjct: 1027 YRL---TVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFT 1083
Query: 801 TRLDAPSQIEV--KDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQY 858
T L S I +VT+TT +ITW P I G +L G++ G ++T D
Sbjct: 1084 T-LQPGSSIPPYNTEVTETTIVITW-TPAPRI-GFKL--GVRPSQGGEAPREVTSDSGSI 1138
Query: 859 SIGNLKPDTEYEVSL-ISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSI-TLEW-RN 915
+ L P EY ++ + R G P T L P NL + D + T+ W R+
Sbjct: 1139 VVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERS 1198
Query: 916 GKAAIDSYRIKYAPISG--GDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKEDKE 973
I YRI P +G G+ E V Q + T L PG EY + V VK+DKE
Sbjct: 1199 TTPDITGYRITTTPTNGQQGNSLEEVVHADQ---SSCTFDNLSPGLEYNVSVYTVKDDKE 1255
Query: 974 SNPATINAATELDTPKDLQVSETAETSLTLLWKTPLA-KFDRYRLNYSLPTGQ--WVGVQ 1030
S P + + P DL+ + ++ + W P + + + YS + +
Sbjct: 1256 SVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELS 1315
Query: 1031 LPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTEQAPELENLTVTEVGWDGL 1090
+ + + VL L PG EY V +++ +H+S P R + T + +++ +
Sbjct: 1316 ISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFSDITANSF 1374
Query: 1091 RLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVIQG 1150
++W A + I+ + R VP S ++ + L T Y VSI +
Sbjct: 1375 TVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR 1434
Query: 1151 YRTPVLSAEAST-GETPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEADTVEAAQ 1209
+P+L + ST + P EVV A +L ++W AP Y+ I E Q
Sbjct: 1435 EESPLLIGQQSTVSDVPRDLEVVAATP--TSLLISWDAPAVTVRYYRITYGETGGNSPVQ 1492
Query: 1210 NLTVPGGLRSTDLPGLKAATHYTITIRGVT----QDFSTTPLSVEVLTEEVPDMGNLTVT 1265
TVPG + + GLK YTIT+ VT S+ P+S+ T E+ + VT
Sbjct: 1493 EFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRT-EIDKPSQMQVT 1551
Query: 1266 EVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTVT 1325
+V +++ + W + + + T M I GL+ Y V+
Sbjct: 1552 DVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVS 1611
Query: 1326 LHGEVRGHSTRPLAVEVVTE-DLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQVQEV 1384
++ + ++PL VT D P+ LA ++V D +++ W + + +
Sbjct: 1612 VYAQNPSGESQPLVQTAVTNIDRPK--GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSP 1669
Query: 1385 NKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEASTAKEPEIGNL 1444
G ++ GL + Y VS+ + + L STA P +L
Sbjct: 1670 EDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTA-IPAPTDL 1728
Query: 1445 NVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTAHISGLPPSTDF 1504
+ +TP S + W + + + + + E N++ + +SGL +T +
Sbjct: 1729 KFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKY 1788
Query: 1505 IVYLSGLAPSIRTKTISATATTEALPLLENLT------ISDINPYGFTVSWMASENAFDS 1558
V + L ++ ++ TT LEN++ ++D T+SW
Sbjct: 1789 EVSVYALKDTLTSRPAQGVVTT-----LENVSPPRRARVTDATETTITISWRTKTETITG 1843
Query: 1559 FLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFTQGHQTKPLRAEIVTE 1618
F V V + P + T+ R + GL G Y++ + ++ P +V +
Sbjct: 1844 FQVDAVPANG-QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP----VVID 1898
Query: 1619 AEPEVD---NLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQSEPLEITLLAPERTR 1675
A +D NL TP+ +SW +++K K S P E+
Sbjct: 1899 ASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYE--KPGSPPREVVPRPRPGVT 1956
Query: 1676 D--ITGLREATEYEIELYGISKGRRSQ 1700
+ ITGL TEY I + + ++S+
Sbjct: 1957 EATITGLEPGTEYTIYVIALKNNQKSE 1983
Score = 270 bits (689), Expect = 2e-71
Identities = 277/1182 (23%), Positives = 475/1182 (40%), Gaps = 87/1182 (7%)
Query: 856 NQYSIGNLKPDTEYEVSLIS---------RRGDMS----SNPAKETFTTGLDAPRN-LRR 901
N Y+I LKP YE LIS R D + S P TG P + L
Sbjct: 664 NSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVA 723
Query: 902 VSQ-----TDNSITLEWRNGKAAIDSYRIKYAPISGGDHAE-VDVPKSQQATTKTTLTGL 955
S+ T +S + W + + +R++Y GD + +D+P + T + L
Sbjct: 724 TSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPST---ATSVNIPDL 780
Query: 956 RPGTEYGIGVSAVKEDKESNPA-TINAATELDTPKDLQVSETAETSLTLLWKTPLAKFDR 1014
PG +Y + V + ED E + + + T D P D V + +TS+ + W P A
Sbjct: 781 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
Query: 1015 YRLNYSLPT-GQWVGVQLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKAST-- 1071
YR+ YS G + LP S L L+PG +YN+ + A + +S P ++ T
Sbjct: 841 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
Query: 1072 ----EQAPELENLTVTEVGWDGLRLNWTAADQAYEHFIIQVQEANKV-EAARNLTVPGSL 1126
+ P +L EV + + WT + A + + V N E + L + +
Sbjct: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
Query: 1127 RAVDIPGLKAATPYTVSIYGVIQGYRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWT 1186
A ++ GL Y ++ V G + L+A+ +T V E L + WT
Sbjct: 961 FA-EVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVL-VRWT 1018
Query: 1187 APEGAYEYFFIQVQEADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTP 1246
P + + V + Q P + L L+ A+ YT+++ + + +P
Sbjct: 1019 PPRAQITGYRLTVGLTRRGQPRQYNVGPS-VSKYPLRNLQPASEYTVSLVAIKGN-QESP 1076
Query: 1247 LSVEVLTEEVPDMGNLTV-TEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVP 1305
+ V T P TEV+ + + WT F + V+ + E +T
Sbjct: 1077 KATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI--GFKLGVRPSQGGEAPREVTSD 1134
Query: 1306 GSLRSMEIPGLRAGTPYTVTLHGEVRGHST-RPLAVEVVTEDLPQLG-------DLAVSE 1357
S+ + GL G Y T+ G P+ +VVT P D V
Sbjct: 1135 SG--SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLT 1192
Query: 1358 VGWD--------GLRLNWTAADNAYEHFVIQVQEVNKVEAA-QNLTLPGSLRAVDIPGLE 1408
V W+ G R+ T + + + +V ++ NL+ PGLE
Sbjct: 1193 VSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLS----------PGLE 1242
Query: 1409 AATPYRVSIYGVIRGYRTPVLSAEASTAKEPEIGNLNVSDITPESFNLSWMATDGIFET- 1467
Y VS+Y ++ + V ++ P +L ++I P++ ++W I T
Sbjct: 1243 ----YNVSVY-TVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTN 1297
Query: 1468 FTIEIIDSNRLLETVEYNISGAERTAHISGLPPSTDFIVYLSGLAPSIRTKTISATATTE 1527
F + + E +IS ++ ++ L P T+++V +S + + + T
Sbjct: 1298 FLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT- 1356
Query: 1528 ALPLLENLTISDINPYGFTVSWMASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELR 1587
L + SDI FTV W+A + + P+E + ++ + L
Sbjct: 1357 GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLT 1416
Query: 1588 GLITGIGYEVMVSGFTQGHQTKPLRAEIVTEAEPEVDNLLVSDATPDGFRLSWTADEGVF 1647
L G Y V + G + PL + +L V ATP +SW A
Sbjct: 1417 NLTPGTEYVVSIVALN-GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTV 1475
Query: 1648 DNFVLKIRDTKKQSEPLEITLLAPERTRDITGLREATEYEIELYGISKGR-----RSQTV 1702
+ + +T S E T+ + T I+GL+ +Y I +Y ++ GR S+ +
Sbjct: 1476 RYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVT-GRGDSPASSKPI 1534
Query: 1703 SAIATTAMGSPKEVIFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSMVTVDGT-K 1761
S T + P ++ +D+ +NS +V W ++ V +R+T P G P+ G +
Sbjct: 1535 SINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1594
Query: 1762 TQTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTTALDGPSGLVTANITDSEALARWQP 1821
T+ + L P VEY+VS+ A ES+P+ + T +D P GL ++ W+
Sbjct: 1595 TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWES 1654
Query: 1822 AIATVDSYVISYTGEK--VPEITRTVSGNTVEYALTDLEPATEYTLRIFAEKGPQKSSTI 1879
V Y ++Y+ + + E+ G L L P +EYT+ + A +S +
Sbjct: 1655 PQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPL 1714
Query: 1880 TAKFTTDLDSPRDLTATEVQSETALLTWRPPRASVTGYLL--VYESVDGTVKEVIVGPDT 1937
+T + +P DL T+V + W PP +TGY + + G +KE+ + PD+
Sbjct: 1715 IGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDS 1774
Query: 1938 TSYSLADLSPSTHYTAKIQALNGPLRSNMIQTIFTTIGLLYP 1979
+S ++ L +T Y + AL L S Q + TT+ + P
Sbjct: 1775 SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSP 1816
Score = 256 bits (654), Expect = 2e-67
Identities = 251/1095 (22%), Positives = 446/1095 (40%), Gaps = 51/1095 (4%)
Query: 632 TEVTEETVNLAWDNEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTIIQELEPGVEYFIR 691
TEVTE T+ + W R+ L V P+ G E V D S ++ L PGVEY
Sbjct: 1096 TEVTETTIVITWTPAPRIGFKLGV-RPSQGG--EAPREVTSDSGSIVVSGLTPGVEYVYT 1152
Query: 692 VFAILENK-KSIPVSARVATYLPAPEGLKFKSIKETSV-EVEWDPLDIAFET-WEIIFRN 748
+ + + + + P+ +V T L P L ++ +T V V W+ T + I
Sbjct: 1153 IQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTP 1212
Query: 749 MNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNNTRGPGLKRVTTTRLDAPSQ 808
N + + + + ++S L+PG EY +S++ VK++ + + P+
Sbjct: 1213 TNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTD 1272
Query: 809 IEVKDVTDTTALITWFKPLA-EIDGIELTYGIKDVPGDRTTIDLTEDENQYSIGNLKPDT 867
+ ++ T +TW P + ++ + Y D + ++ +N + NL P T
Sbjct: 1273 LRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGT 1332
Query: 868 EYEVSLISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSITLEWRNGKAAIDSYRIKY 927
EY VS+ S S P + TGLD+P + T NS T+ W +A I YRI++
Sbjct: 1333 EYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRH 1392
Query: 928 APIS-GGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKEDKESNPATINAATELD 986
P G E VP S+ + T T LT PGTEY + + A+ +ES +T D
Sbjct: 1393 HPEHFSGRPREDRVPHSRNSITLTNLT---PGTEYVVSIVALNGREESPLLIGQQSTVSD 1449
Query: 987 TPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYSLPTGQWVGVQ---LPRNTTSYVLRGL 1043
P+DL+V TSL + W P YR+ Y TG VQ +P + ++ + GL
Sbjct: 1450 VPRDLEVVAATPTSLLISWDAPAVTVRYYRITYG-ETGGNSPVQEFTVPGSKSTATISGL 1508
Query: 1044 EPGQEYNVLLTAEKGRH----KSKPARVKASTEQAPELENLTVTEVGWDGLRLNWTAADQ 1099
+PG +Y + + A GR SKP + TE + + VT+V + + + W +
Sbjct: 1509 KPGVDYTITVYAVTGRGDSPASSKPISINYRTE-IDKPSQMQVTDVQDNSISVKWLPSSS 1567
Query: 1100 AYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVI-QGYRTPVLSA 1158
+ + N + T + I GL+ Y VS+Y G P++
Sbjct: 1568 PVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQT 1627
Query: 1159 EASTGETPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEADTVEAAQNLTVPGGLR 1218
+ + P + +V D++K+ W +P+G + + + + P G
Sbjct: 1628 AVTNIDRPK--GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPED-GIHELFPAPDGEE 1684
Query: 1219 ST-DLPGLKAATHYTITIRGVTQDFSTTPLSVEVLTEEVPDMGNLTVTEVSWDALRLNWT 1277
T +L GL+ + YT+++ + D + PL + + +P +L T+V+ +L WT
Sbjct: 1685 DTAELQGLRPGSEYTVSVVALHDDMESQPL-IGTQSTAIPAPTDLKFTQVTPTSLSAQWT 1743
Query: 1278 TPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTVTLHGEVRGHSTRP 1337
P+ + ++V ++ + + S+ + GL T Y V+++ ++RP
Sbjct: 1744 PPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRP 1803
Query: 1338 LAVEVVT-EDLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQVQEVNKVEAAQNLTLP 1396
V T E++ V++ + ++W F + N Q T+
Sbjct: 1804 AQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQR-TIK 1862
Query: 1397 GSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEASTAKEPEIGNLNVSDITPESFNL 1456
+R+ I GL+ T Y++ +Y + R+ + +ASTA + NL TP S +
Sbjct: 1863 PDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAP-SNLRFLATTPNSLLV 1921
Query: 1457 SWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTAHISGLPPSTDFIVYLSGLAPSIR 1516
SW + I+ V A I+GL P T++ +Y+ L + +
Sbjct: 1922 SWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQK 1981
Query: 1517 TKTISATATTEALPLLENLTISDINPYGFTVSWMASENAFDSFLVTVVDSGKLLDPQEFT 1576
++ + T+ LP L +T+ N +G + + S TV + + P T
Sbjct: 1982 SEPLIGRKKTDELPQL--VTLPHPNLHGPEILDVPS---------TVQKTPFVTHPGYDT 2030
Query: 1577 LSGTQRKLELRGLITGIGYEVMVSGFTQGHQTKPLRAEIVTEA----EPEVDNLLVSDAT 1632
+G Q G +G +++ T P A + P V +S T
Sbjct: 2031 GNGIQLP-GTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTT 2089
Query: 1633 PDGFRLSWTADEGVFDNFVLKIRDTKKQSEPLEITLLAPERTRDITGLREATEYEIELYG 1692
+SW + +++ EPL+ + + +TGL Y I +
Sbjct: 2090 -----ISWAPFQDT-SEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEA 2143
Query: 1693 ISKGRRSQTVSAIAT 1707
+ +R + + T
Sbjct: 2144 LKDQQRHKVREEVVT 2158
Score = 240 bits (612), Expect = 1e-62
Identities = 247/1064 (23%), Positives = 437/1064 (41%), Gaps = 90/1064 (8%)
Query: 623 VSPPKDLVVTEVTEET--VNLAWDNEMR--VTEYLVVYTPTH-EGGLEMQFRVPGDQTST 677
+SPP +L + E +T + ++W+ +T Y + TPT+ + G ++ V DQ+S
Sbjct: 1174 LSPPTNLHL-EANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSC 1232
Query: 678 IIQELEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPLDI 737
L PG+EY + V+ + ++K+S+P+S + +P P L+F +I ++ V W P
Sbjct: 1233 TFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPS 1292
Query: 738 AFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNNTRGPGLKR 797
T ++ + K +E S+ + + T L PG EY +S+ V L+
Sbjct: 1293 IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRG 1352
Query: 798 VTTTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQ 857
T LD+P+ I+ D+T + + W P A I G + + + G + N
Sbjct: 1353 RQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNS 1412
Query: 858 YSIGNLKPDTEYEVSLISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSITLEWRNGK 917
++ NL P TEY VS+++ G S +T D PR+L V+ T S+ + W
Sbjct: 1413 ITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPA 1472
Query: 918 AAIDSYRIKYAPISGGDHA-EVDVPKSQQATTKTTLTGLRPGTEYGIGVSAV----KEDK 972
+ YRI Y G E VP S+ + T++GL+PG +Y I V AV
Sbjct: 1473 VTVRYYRITYGETGGNSPVQEFTVPGSK---STATISGLKPGVDYTITVYAVTGRGDSPA 1529
Query: 973 ESNPATINAATELDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYSLPTGQWVGVQLP 1032
S P +IN TE+D P +QV++ + S+++ W + YR+ + G P
Sbjct: 1530 SSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPG-----P 1584
Query: 1033 RNT-------TSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTEQAPELENLTVTEV 1085
T T + GL+P EY V + A+ +S+P V+ + + L T+V
Sbjct: 1585 TKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL-VQTAVTNIDRPKGLAFTDV 1643
Query: 1086 GWDGLRLNWTAADQAYEHFIIQVQEANKVEAARNL--TVPGSLRAVDIPGLKAATPYTVS 1143
D +++ W + + +V ++ + L G ++ GL+ + YTVS
Sbjct: 1644 DVDSIKIAWESPQGQVSRY--RVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVS 1701
Query: 1144 IYGVIQGYRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEAD 1203
+ + + L ST P ++ +V +L WT P + ++V +
Sbjct: 1702 VVALHDDMESQPLIGTQSTA-IPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKE 1760
Query: 1204 TVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLT-EEVPDMGNL 1262
+ + + S + GL AT Y +++ + ++ P V T E V
Sbjct: 1761 KTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRA 1820
Query: 1263 TVTEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTPY 1322
VT+ + + ++W T T F + A+ + T+ +RS I GL+ GT Y
Sbjct: 1821 RVTDATETTITISWRTKTETITGFQVDAVPANG-QTPIQRTIKPDVRSYTITGLQPGTDY 1879
Query: 1323 TVTLHGEVRGHSTRPLAVEVVTE-DLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQV 1381
+ L+ + P+ ++ T D P +L + L ++W ++I+
Sbjct: 1880 KIYLYTLNDNARSSPVVIDASTAIDAP--SNLRFLATTPNSLLVSWQPPRARITGYIIKY 1937
Query: 1382 QEV-NKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEASTAKEPE 1440
++ + PG A I GLE T Y +IY V++ + + EP
Sbjct: 1938 EKPGSPPREVVPRPRPGVTEAT-ITGLEPGTEY--TIY---------VIALKNNQKSEPL 1985
Query: 1441 IGNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTAHISGLPP 1500
IG ++ P+ L G EI+D ++ + T + LP
Sbjct: 1986 IGRKKTDEL-PQLVTLPHPNLHG------PEILDVPSTVQKTPFVTHPGYDTGNGIQLPG 2038
Query: 1501 STDFIVYLSGLAPSIRTKTI-------SATATTEALPLLEN-----LTISDINPYGFTVS 1548
+ SG PS+ + I T T A P+ + T+S
Sbjct: 2039 T-------SGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTIS 2091
Query: 1549 WMASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFTQGHQT 1608
W ++ ++++ G +P +F + GT L GL G Y ++V + Q
Sbjct: 2092 WAPFQDT-SEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEAL-KDQQR 2149
Query: 1609 KPLRAEIVTEAEPEVDNLLVSDATPDGFRLSWTADEGVFDNFVL 1652
+R E+VT V ++ +G L+ D+ FD + +
Sbjct: 2150 HKVREEVVT----------VGNSVNEG--LNQPTDDSCFDPYTV 2181
Score = 217 bits (552), Expect = 1e-55
Identities = 186/819 (22%), Positives = 340/819 (41%), Gaps = 47/819 (5%)
Query: 617 GEDCSEVSPPKDLVVTEVTEETVNLAW-DNEMRVTEYLVVYTPTHEGGLEMQFRVPGDQT 675
G + + P + +++T + + W +T Y + + P H G + RVP +
Sbjct: 1352 GRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRN 1411
Query: 676 STIIQELEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPL 735
S + L PG EY + + A+ ++S + + +T P L+ + TS+ + WD
Sbjct: 1412 SITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP 1471
Query: 736 DIAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNNTRGPGL 795
+ + I + + ++ +++ +GL PG +Y I+++ V P
Sbjct: 1472 AVTVRYYRITYGETGGNSPVQ-EFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPAS 1530
Query: 796 KRVTT----TRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDL 851
+ + T +D PSQ++V DV D + + W + + G +T K+ PG T
Sbjct: 1531 SKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTA 1590
Query: 852 TEDENQYSIGNLKPDTEYEVSLISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSITL 911
D+ + +I L+P EY VS+ ++ S P +T T +D P+ L +SI +
Sbjct: 1591 GPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKI 1650
Query: 912 EWRNGKAAIDSYRIKYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKED 971
W + + + YR+ Y+ G H P ++ T + L GLRPG+EY + V A+ +D
Sbjct: 1651 AWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAE--LQGLRPGSEYTVSVVALHDD 1708
Query: 972 KESNPATINAATELDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYS--LPTGQWVGV 1029
ES P +T + P DL+ ++ TSL+ W P + YR+ + TG +
Sbjct: 1709 MESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEI 1768
Query: 1030 QLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPAR-VKASTEQAPELENLTVTEVGWD 1088
L +++S V+ GL +Y V + A K S+PA+ V + E VT+
Sbjct: 1769 NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATET 1828
Query: 1089 GLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVI 1148
+ ++W + F + AN + T+ +R+ I GL+ T Y + +Y +
Sbjct: 1829 TITISWRTKTETITGFQVDAVPANG-QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1887
Query: 1149 QGYRTPVLSAEASTG-ETP-NLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEADTVE 1206
R+ + +AST + P NL + ++L ++W P + I+ ++ +
Sbjct: 1888 DNARSSPVVIDASTAIDAPSNLRFLATTP---NSLLVSWQPPRARITGYIIKYEKPGSPP 1944
Query: 1207 AAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLTEEVPDMGNL---- 1262
G+ + GL+ T YTI + + + + PL T+E+P + L
Sbjct: 1945 REVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPN 2004
Query: 1263 ----TVTEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRA 1318
+ +V + + T G IQ+ + + G E G R
Sbjct: 2005 LHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPS-----VGQQMIFEEHGFRR 2059
Query: 1319 GTPYTVTLHGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFV 1378
TP T +R H RP P +G A+S+ ++W + E ++
Sbjct: 2060 TTPPTTAT--PIR-HRPRPYP--------PNVGQEALSQT-----TISWAPFQDTSE-YI 2102
Query: 1379 IQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSI 1417
I V E +PG+ + + GL Y + +
Sbjct: 2103 ISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIV 2141
Score = 187 bits (475), Expect = 1e-46
Identities = 155/570 (27%), Positives = 255/570 (44%), Gaps = 54/570 (9%)
Query: 621 SEVSPPKDLVVTEVTEETVNLAWDNEM-RVTEYLVVYTPTHEGGLEMQFRVPGDQTSTII 679
+ + PK L T+V +++ +AW++ +V+ Y V Y+ +G E+ G++ + +
Sbjct: 1630 TNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAEL 1689
Query: 680 QELEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPLDIAF 739
Q L PG EY + V A+ ++ +S P+ +T +PAP LKF + TS+ +W P ++
Sbjct: 1690 QGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQL 1749
Query: 740 ETWEIIFRNMNKEDEGEITKSLRRPETS-YRQTGLAPGQEYEISLHIVKNNTRGPGLKRV 798
+ + R KE G + + P++S +GL +YE+S++ +K+ + V
Sbjct: 1750 TGYRV--RVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV 1807
Query: 799 TTT--RLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGD-RTTIDLT--E 853
TT + P + V D T+TT I+W I G + + VP + +T I T
Sbjct: 1808 VTTLENVSPPRRARVTDATETTITISWRTKTETITGFQ----VDAVPANGQTPIQRTIKP 1863
Query: 854 DENQYSIGNLKPDTEYEVSLISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSITLEW 913
D Y+I L+P T+Y++ L + + S+P +T +DAP NLR ++ T NS+ + W
Sbjct: 1864 DVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSW 1923
Query: 914 RNGKAAIDSYRIKYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKEDKE 973
+ +A I Y IKY G EV VP+ + T+ T+TGL PGTEY I V A+K +++
Sbjct: 1924 QPPRARITGYIIKYEK-PGSPPREV-VPRPRPGVTEATITGLEPGTEYTIYVIALKNNQK 1981
Query: 974 SNPATINAATE------------LDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYSL 1021
S P T+ L P+ L V T + KTP Y
Sbjct: 1982 SEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQ-------KTPFVTHPGY------ 2028
Query: 1022 PTGQWVGVQLPRNTTSYVLRGLEP--GQEYNVLLTAEKGRHKSKPARVKASTEQAPELEN 1079
TG G+QLP + G +P GQ+ ++ E G ++ P P
Sbjct: 2029 DTGN--GIQLPGTS------GQQPSVGQQ---MIFEEHGFRRTTPPTTATPIRHRPRPYP 2077
Query: 1080 LTVTEVGWDGLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATP 1139
V + ++W A Q +II E VPG+ + + GL
Sbjct: 2078 PNVGQEALSQTTISW-APFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGAT 2136
Query: 1140 YTVSIYGVIQGYRTPVLSAEASTGETPNLG 1169
Y + + + R V + G + N G
Sbjct: 2137 YNIIVEALKDQQRHKVREEVVTVGNSVNEG 2166
Score = 153 bits (386), Expect = 2e-36
Identities = 147/662 (22%), Positives = 264/662 (39%), Gaps = 40/662 (6%)
Query: 1365 LNWTAADNAY-EHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIR- 1422
+ W A ++ ++++ + N V + T+PG L + I GL+ Y + + +
Sbjct: 628 IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687
Query: 1423 GYR-------------TPVLSAEASTAKEP----EIGNLNVSDITPESFNLSWMATDGIF 1465
G++ TPV S + P + +V++IT SF +SW++
Sbjct: 688 GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747
Query: 1466 ETFTIEIIDSNRLLETVEYNISGAERTAHISGLPPSTDFIVYLSGLAPSIRTKTISATAT 1525
F +E S E ++ + +I L P +IV + ++ I +T+
Sbjct: 748 SGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQ 807
Query: 1526 TEALPLLENLTISDINPYGFTVSWMASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLE 1585
T A + T+ ++ V W + + + S + E L T +
Sbjct: 808 TTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEG-SSTELNLPETANSVT 866
Query: 1586 LRGLITGIGYEVMVSGFTQGHQTKPLRAEIVTEAEPEVD------NLLVSDATPDGFRLS 1639
L L G+ Y + + + ++ P+ + T P D +L + T +
Sbjct: 867 LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926
Query: 1640 WTADEGVFDNFVLKIRDTKKQSEPLEITLLAPERTRDITGLREATEYEIELYGISKGRRS 1699
WT E + + + E + ++ ++TGL Y +++ +S GR S
Sbjct: 927 WTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986
Query: 1700 QTVSAIATTAMGSPKEVIFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSMVTVDG 1759
+ ++A TT + +P + F + T+++ V W P AQ+ +R+T G P V
Sbjct: 987 KPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGP 1046
Query: 1760 TKTQTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTTALDGPS-GLVTANITDSEALAR 1818
+ ++ L L P EY VS++A+KG +ES +G FTT G S +T++ +
Sbjct: 1047 SVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVIT 1106
Query: 1819 WQPAIATVDSYVISYTGEKVPEITRTVSGNTVEYALTDLEPATEYTLRI-FAEKGPQKSS 1877
W PA + + + E R V+ ++ ++ L P EY I G ++ +
Sbjct: 1107 WTPAPRI--GFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDA 1164
Query: 1878 TITAKFTTDLDSPRDLTATEVQSETALLT--W-RPPRASVTGYLLVYESVD---GTVKEV 1931
I K T L P +L E +T +LT W R +TGY + + G E
Sbjct: 1165 PIVNKVVTPLSPPTNL-HLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEE 1223
Query: 1932 IVGPDTTSYSLADLSPSTHYTAKIQALNGPLRSNMIQTIFTTIGLLYPFPKDCSQAMLNG 1991
+V D +S + +LSP Y + + S I TI P P D +
Sbjct: 1224 VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKES---VPISDTIIPAVPPPTDLRFTNIGP 1280
Query: 1992 DT 1993
DT
Sbjct: 1281 DT 1282
>gi|47132555 fibronectin 1 isoform 4 preproprotein [Homo sapiens]
Length = 2330
Score = 360 bits (925), Expect = 6e-99
Identities = 325/1394 (23%), Positives = 584/1394 (41%), Gaps = 73/1394 (5%)
Query: 624 SPPKDLVVTEVTEETVN--LAWD--NEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTII 679
S P ++ +TE + + + W+ +++Y++ + P + G + +PG S I
Sbjct: 609 SGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTI 668
Query: 680 QELEPGVEYFIRVFAILE-------------NKKSIPVSARVATYLPAP------EGLKF 720
+ L+PGV Y ++ +I + S PV++ T P
Sbjct: 669 KGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESV 728
Query: 721 KSIKETSVEVEWDPLDIAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYE 780
I +S V W + + + + DE + L TS L PG++Y
Sbjct: 729 TEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYL-DLPSTATSVNIPDLLPGRKYI 787
Query: 781 ISLH-IVKNNTRGPGLKRVTTTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGI 839
++++ I ++ + L TT DAP V V DT+ ++ W +P A I G + Y
Sbjct: 788 VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYS- 846
Query: 840 KDVPGDRTTIDLTEDENQYSIGNLKPDTEYEVSLISRRGDMSSNPAK-ETFTTG------ 892
V G T ++L E N ++ +L+P +Y +++ + + S P + TTG
Sbjct: 847 PSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDT 906
Query: 893 LDAPRNLRRVSQTDNSITLEWRNGKAAIDSYRIKYAPIS-GGDHAEVDVPKSQQATTKTT 951
+ +PR+L+ V TD +T+ W ++A+ YR+ P++ G+H + +P S+ T
Sbjct: 907 VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQ-RLPISRN--TFAE 963
Query: 952 LTGLRPGTEYGIGVSAVKEDKESNPATINAATELDTPKDLQVSETAETSLTLLWKTPLAK 1011
+TGL PG Y V AV +ES P T T+LD P +LQ ++++ + W P A+
Sbjct: 964 VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQ 1023
Query: 1012 FDRYRLNYSLPT-GQWVGVQLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKAS 1070
YRL L GQ + + + Y LR L+P EY V L A KG +S A +
Sbjct: 1024 ITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFT 1083
Query: 1071 TEQAPELENLTVTEVGWDGLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVD 1130
T Q TEV + + WT A + F + V+ + EA R +T ++
Sbjct: 1084 TLQPGSSIPPYNTEVTETTIVITWTPAPRI--GFKLGVRPSQGGEAPREVTSDSG--SIV 1139
Query: 1131 IPGLKAATPYTVSIYGVIQGYR--TPVLSAEASTGETPNLGEVVVAEVGWDALKLNW--- 1185
+ GL Y +I + G P+++ + T +P + A L ++W
Sbjct: 1140 VSGLTPGVEYVYTIQVLRDGQERDAPIVN-KVVTPLSPPTNLHLEANPDTGVLTVSWERS 1198
Query: 1186 TAPE-GAYEYFFIQV--QEADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDF 1242
T P+ Y Q+ +++E V S L Y +++ V D
Sbjct: 1199 TTPDITGYRITTTPTNGQQGNSLEEV----VHADQSSCTFDNLSPGLEYNVSVYTVKDDK 1254
Query: 1243 STTPLSVEVLTEEVPDMGNLTVTEVSWDALRLNWTTPDGT-YDQFTIQVQEADQVEEAHN 1301
+ P+S + + VP +L T + D +R+ W P F ++ E+
Sbjct: 1255 ESVPIS-DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE 1313
Query: 1302 LTVPGSLRSMEIPGLRAGTPYTVTLHGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWD 1361
L++ S ++ + L GT Y V++ H + PL T L + S++ +
Sbjct: 1314 LSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFSDITAN 1372
Query: 1362 GLRLNWTAADNAYEHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVI 1421
++W A + I+ + + +P S ++ + L T Y VSI +
Sbjct: 1373 SFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN 1432
Query: 1422 RGYRTPVLSAEASTAKEPEIGNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLET 1481
+P+L + ST + +L V TP S +SW A + I ++
Sbjct: 1433 GREESPLLIGQQSTVSDVP-RDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPV 1491
Query: 1482 VEYNISGAERTAHISGLPPSTDFIVYL-----SGLAPSIRTKTISATATTEALPLLENLT 1536
E+ + G++ TA ISGL P D+ + + G +P+ +K IS TE + +
Sbjct: 1492 QEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPA-SSKPISINYRTE-IDKPSQMQ 1549
Query: 1537 ISDINPYGFTVSWMASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYE 1596
++D+ +V W+ S + + VT + T Q ++ + GL + Y
Sbjct: 1550 VTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYV 1609
Query: 1597 VMVSGFTQGHQTKPLRAEIVTEAEPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRD 1656
V V +++PL VT + L +D D +++W + +G + +
Sbjct: 1610 VSVYAQNPSGESQPLVQTAVTNID-RPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSS 1668
Query: 1657 TKKQSEPLEITLLAPERTRDITGLREATEYEIELYGISKGRRSQTVSAIATTAMGSPKEV 1716
+ L E T ++ GLR +EY + + + SQ + +TA+ +P ++
Sbjct: 1669 PEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDL 1728
Query: 1717 IFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSM-VTVDGTKTQTRLVKLIPGVEY 1775
F+ +T S + W P Q+ +R+ P P + + + + L+ +Y
Sbjct: 1729 KFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKY 1788
Query: 1776 LVSIIAMKGFEESEPVSGSFTTA--LDGPSGLVTANITDSEALARWQPAIATVDSYVI-S 1832
VS+ A+K S P G TT + P + T++ W+ T+ + + +
Sbjct: 1789 EVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDA 1848
Query: 1833 YTGEKVPEITRTVSGNTVEYALTDLEPATEYTLRIFAEKGPQKSSTITAKFTTDLDSPRD 1892
I RT+ + Y +T L+P T+Y + ++ +SS + +T +D+P +
Sbjct: 1849 VPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSN 1908
Query: 1893 LTATEVQSETALLTWRPPRASVTGYLLVYESVDGTVKEVI--VGPDTTSYSLADLSPSTH 1950
L + L++W+PPRA +TGY++ YE +EV+ P T ++ L P T
Sbjct: 1909 LRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTE 1968
Query: 1951 YTAKIQALNGPLRS 1964
YT + AL +S
Sbjct: 1969 YTIYVIALKNNQKS 1982
Score = 340 bits (872), Expect = 9e-93
Identities = 309/1304 (23%), Positives = 528/1304 (40%), Gaps = 79/1304 (6%)
Query: 631 VTEVTEETVNLAWDNEM-RVTEYLVVYTPTHEGGLEMQFRVPGDQTSTIIQELEPGVEYF 689
VTE+T + ++W + V+ + V Y + EG +P TS I +L PG +Y
Sbjct: 728 VTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYI 787
Query: 690 IRVFAILEN-KKSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPLDIAFETWEIIFRN 748
+ V+ I E+ ++S+ +S T AP + +TS+ V W + I++
Sbjct: 788 VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVY-- 845
Query: 749 MNKEDEGEITKSLRRPETSYRQT--GLAPGQEYEISLHIVKNNTRGPGL----KRVTTTR 802
+ EG T+ L PET+ T L PG +Y I+++ V+ N + + T R
Sbjct: 846 -SPSVEGSSTE-LNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPR 903
Query: 803 LD---APSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQYS 859
D +P ++ +VTD I W P + + G + ++PG+ L N ++
Sbjct: 904 SDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQ-RLPISRNTFA 962
Query: 860 -IGNLKPDTEYEVSLISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSITLEWRNGKA 918
+ L P Y + + S P TT LDAP NL+ V++TD+++ + W +A
Sbjct: 963 EVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRA 1022
Query: 919 AIDSYRIKYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKEDKESNPAT 978
I YR+ G + +V S +K L L+P +EY + + A+K ++ES AT
Sbjct: 1023 QITGYRLTVGLTRRGQPRQYNVGPS---VSKYPLRNLQPASEYTVSLVAIKGNQESPKAT 1079
Query: 979 INAATELDTPKDLQV--SETAETSLTLLWKTPLAKFDRYRLNYSLPTGQWVGVQLPRNTT 1036
T L + +E ET++ + W TP R+ + L G + PR T
Sbjct: 1080 -GVFTTLQPGSSIPPYNTEVTETTIVITW-TPAP-----RIGFKLGVRPSQGGEAPREVT 1132
Query: 1037 S----YVLRGLEPGQEY-NVLLTAEKGRHKSKPARVKASTEQAPELE-------NLTVTE 1084
S V+ GL PG EY + G+ + P K T +P + V
Sbjct: 1133 SDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLT 1192
Query: 1085 VGWD--------GLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKA 1136
V W+ G R+ T + + + +V A++ + PG
Sbjct: 1193 VSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPG------------ 1240
Query: 1137 ATPYTVSIYGVIQGYRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWTAPEGA-YEYF 1195
Y VS+Y ++ + V ++ P ++ +G D +++ W P F
Sbjct: 1241 -LEYNVSVY-TVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNF 1298
Query: 1196 FIQVQEADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLTEE 1255
++ E L++ + L L T Y +++ V + +TPL T
Sbjct: 1299 LVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL 1358
Query: 1256 VPDMGNLTVTEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPG 1315
G + ++++ ++ ++W P T + I+ VP S S+ +
Sbjct: 1359 DSPTG-IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1417
Query: 1316 LRAGTPYTVTLHGEVRGHSTRPLAV--EVVTEDLPQLGDLAVSEVGWDGLRLNWTAADNA 1373
L GT Y V++ + G PL + + D+P+ DL V L ++W A
Sbjct: 1418 LTPGTEYVVSIVA-LNGREESPLLIGQQSTVSDVPR--DLEVVAATPTSLLISWDAPAVT 1474
Query: 1374 YEHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEA 1433
++ I E Q T+PGS I GL+ Y +++Y V +P S
Sbjct: 1475 VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPI 1534
Query: 1434 STAKEPEI---GNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAE 1490
S EI + V+D+ S ++ W+ + + + N T +
Sbjct: 1535 SINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1594
Query: 1491 RTAHISGLPPSTDFIVYLSGLAPSIRTKTISATATTEALPLLENLTISDINPYGFTVSWM 1550
I GL P+ +++V + PS ++ + TA T + + L +D++ ++W
Sbjct: 1595 TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTN-IDRPKGLAFTDVDVDSIKIAWE 1653
Query: 1551 ASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFTQGHQTKP 1610
+ + + VT + G + EL+GL G Y V V +++P
Sbjct: 1654 SPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQP 1713
Query: 1611 LRAEIVTEAEPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQSEPLEITLLA 1670
L T A P +L + TP WT + +++ +K EI L
Sbjct: 1714 LIGTQST-AIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAP 1772
Query: 1671 PERTRDITGLREATEYEIELYGISKGRRSQTVSAIATTA--MGSPKEVIFSDITENSATV 1728
+ ++GL AT+YE+ +Y + S+ + TT + P+ +D TE + T+
Sbjct: 1773 DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITI 1832
Query: 1729 SWRAPTAQVESFRITYVPITGGTPSMVTVDGTKTQTRLVKLIPGVEYLVSIIAMKGFEES 1788
SWR T + F++ VP G TP T+ + L PG +Y + + + S
Sbjct: 1833 SWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARS 1892
Query: 1789 EPVSGSFTTALDGPSGLVTANITDSEALARWQPAIATVDSYVISY--TGEKVPEITRTVS 1846
PV +TA+D PS L T + L WQP A + Y+I Y G E+
Sbjct: 1893 SPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPR 1952
Query: 1847 GNTVEYALTDLEPATEYTLRIFAEKGPQKSSTITAKFTTDLDSP 1890
E +T LEP TEYT+ + A K QKS + + T +P
Sbjct: 1953 PGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTP 1996
Score = 313 bits (803), Expect = 9e-85
Identities = 308/1264 (24%), Positives = 532/1264 (42%), Gaps = 96/1264 (7%)
Query: 767 SYRQTGLAPGQEYEISLHIVKN--------------NTRGPGLKRVTTTRLDAPSQI--- 809
SY GL PG YE L ++ +T P T S +
Sbjct: 665 SYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVAT 724
Query: 810 --EVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQYSIGNLKPDT 867
V ++T ++ +++W + G + Y + + + +DL +I +L P
Sbjct: 725 SESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGR 784
Query: 868 EYEVSL--ISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSITLEWRNGKAAIDSYRI 925
+Y V++ IS G+ S + TT DAP + D SI + W +A I YRI
Sbjct: 785 KYIVNVYQISEDGEQSLILSTSQ-TTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRI 843
Query: 926 KYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKEDKESNPATINAATE- 984
Y+P G E+++P++ + T L+ L+PG +Y I + AV+E++ES P I T
Sbjct: 844 VYSPSVEGSSTELNLPETANSVT---LSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
Query: 985 ------LDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNY---SLPTGQWVGVQLPRNT 1035
+ +P+DLQ E + +T++W P + YR++ +LP + + RNT
Sbjct: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
Query: 1036 TSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTE-QAPELENLTVTEVGWDGLRLNW 1094
+ V GL PG Y + A +SKP + +T+ AP NL + + W
Sbjct: 961 FAEVT-GLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPT--NLQFVNETDSTVLVRW 1017
Query: 1095 TAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVIQGYRTP 1154
T + + V + + R V S+ + L+ A+ YTVS+ + +P
Sbjct: 1018 TPPRAQITGYRLTVGLTRRGQP-RQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESP 1076
Query: 1155 VLSAEASTGETPNLGEVVVAEVGWDALKLNWT-APEGAYEYFFIQVQEADTVEAAQNLTV 1213
+ +T + + EV + + WT AP ++ + V+ + EA + +T
Sbjct: 1077 KATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFK---LGVRPSQGGEAPREVTS 1133
Query: 1214 PGGLRSTDLPGLKAATHYTITIR----GVTQDFS-----TTPLS--VEVLTEEVPDMGNL 1262
G S + GL Y TI+ G +D TPLS + E PD G L
Sbjct: 1134 DSG--SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVL 1191
Query: 1263 TVTEVSWDALRLNWTTPDGTYDQFTIQV---QEADQVEEAHNLTVPGSLRSMEIPGLRAG 1319
TV SW+ TTPD T + T Q+ + +EE V S L G
Sbjct: 1192 TV---SWERS----TTPDITGYRITTTPTNGQQGNSLEEV----VHADQSSCTFDNLSPG 1240
Query: 1320 TPYTVTLHGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWDGLRLNWTAADNA-YEHFV 1378
Y V+++ + P++ + + +P DL + +G D +R+ W + +F+
Sbjct: 1241 LEYNVSVYTVKDDKESVPIS-DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFL 1299
Query: 1379 IQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEASTAKE 1438
++ V E L++ S AV + L T Y VS+ V + + L T +
Sbjct: 1300 VRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD 1359
Query: 1439 PEIGNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTAHISGL 1498
G ++ SDIT SF + W+A + I + E + + + ++ L
Sbjct: 1360 SPTG-IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNL 1418
Query: 1499 PPSTDFIVYLSGLAPSIRTKT-ISATATTEALPLLENLTISDINPYGFTVSWMASENAFD 1557
P T+++V + L + I +T +P +L + P +SW A
Sbjct: 1419 TPGTEYVVSIVALNGREESPLLIGQQSTVSDVP--RDLEVVAATPTSLLISWDAPAVTVR 1476
Query: 1558 SFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFT----QGHQTKPLRA 1613
+ +T ++G QEFT+ G++ + GL G+ Y + V T +KP+
Sbjct: 1477 YYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISI 1536
Query: 1614 EIVTEAEPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQSE-PLEITLLAPE 1672
TE + + + V+D + + W + ++ T K P + P+
Sbjct: 1537 NYRTEID-KPSQMQVTDVQDNSISVKWLPSSSPVTGY--RVTTTPKNGPGPTKTKTAGPD 1593
Query: 1673 RTR-DITGLREATEYEIELYGISKGRRSQTVSAIATTAMGSPKEVIFSDITENSATVSWR 1731
+T I GL+ EY + +Y + SQ + A T + PK + F+D+ +S ++W
Sbjct: 1594 QTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWE 1653
Query: 1732 APTAQVESFRITYVPITGGTPSMVTV-DGTKTQTRLVKLIPGVEYLVSIIAMKGFEESEP 1790
+P QV +R+TY G + DG + L L PG EY VS++A+ ES+P
Sbjct: 1654 SPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQP 1713
Query: 1791 VSGSFTTALDGPSGLVTANITDSEALARWQPAIATVDSYVISYTGEK----VPEITRTVS 1846
+ G+ +TA+ P+ L +T + A+W P + Y + T ++ + EI
Sbjct: 1714 LIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPD 1773
Query: 1847 GNTVEYALTDLEPATEYTLRIFAEKGPQKSSTITAKFTT--DLDSPRDLTATEVQSETAL 1904
++V ++ L AT+Y + ++A K S TT ++ PR T+ T
Sbjct: 1774 SSSV--VVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTIT 1831
Query: 1905 LTWRPPRASVTGYLLVYESVDG-TVKEVIVGPDTTSYSLADLSPSTHYTAKIQALNGPLR 1963
++WR ++TG+ + +G T + + PD SY++ L P T Y + LN R
Sbjct: 1832 ISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNAR 1891
Query: 1964 SNMI 1967
S+ +
Sbjct: 1892 SSPV 1895
Score = 278 bits (712), Expect = 3e-74
Identities = 272/1120 (24%), Positives = 450/1120 (40%), Gaps = 59/1120 (5%)
Query: 623 VSPPKDLVVTEVTEETVNLAW-DNEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTIIQE 681
V P+DL EVT+ V + W E VT Y V P + G Q T +
Sbjct: 907 VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTG 966
Query: 682 LEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPLDIAFET 741
L PGV Y+ +VFA+ ++S P++A+ T L AP L+F + +++V V W P
Sbjct: 967 LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITG 1026
Query: 742 WEIIFRNMNKEDEGEITKSLRRPETS-YRQTGLAPGQEYEISLHIVKNNTRGPGLKRVTT 800
+ + + G+ + P S Y L P EY +SL +K N P V T
Sbjct: 1027 YRL---TVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFT 1083
Query: 801 TRLDAPSQIEV--KDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQY 858
T L S I +VT+TT +ITW P I G +L G++ G ++T D
Sbjct: 1084 T-LQPGSSIPPYNTEVTETTIVITW-TPAPRI-GFKL--GVRPSQGGEAPREVTSDSGSI 1138
Query: 859 SIGNLKPDTEYEVSL-ISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSI-TLEW-RN 915
+ L P EY ++ + R G P T L P NL + D + T+ W R+
Sbjct: 1139 VVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERS 1198
Query: 916 GKAAIDSYRIKYAPISG--GDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKEDKE 973
I YRI P +G G+ E V Q + T L PG EY + V VK+DKE
Sbjct: 1199 TTPDITGYRITTTPTNGQQGNSLEEVVHADQ---SSCTFDNLSPGLEYNVSVYTVKDDKE 1255
Query: 974 SNPATINAATELDTPKDLQVSETAETSLTLLWKTPLA-KFDRYRLNYSLPTGQ--WVGVQ 1030
S P + + P DL+ + ++ + W P + + + YS + +
Sbjct: 1256 SVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELS 1315
Query: 1031 LPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTEQAPELENLTVTEVGWDGL 1090
+ + + VL L PG EY V +++ +H+S P R + T + +++ +
Sbjct: 1316 ISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFSDITANSF 1374
Query: 1091 RLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVIQG 1150
++W A + I+ + R VP S ++ + L T Y VSI +
Sbjct: 1375 TVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR 1434
Query: 1151 YRTPVLSAEAST-GETPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEADTVEAAQ 1209
+P+L + ST + P EVV A +L ++W AP Y+ I E Q
Sbjct: 1435 EESPLLIGQQSTVSDVPRDLEVVAATP--TSLLISWDAPAVTVRYYRITYGETGGNSPVQ 1492
Query: 1210 NLTVPGGLRSTDLPGLKAATHYTITIRGVT----QDFSTTPLSVEVLTEEVPDMGNLTVT 1265
TVPG + + GLK YTIT+ VT S+ P+S+ T E+ + VT
Sbjct: 1493 EFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRT-EIDKPSQMQVT 1551
Query: 1266 EVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTVT 1325
+V +++ + W + + + T M I GL+ Y V+
Sbjct: 1552 DVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVS 1611
Query: 1326 LHGEVRGHSTRPLAVEVVTE-DLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQVQEV 1384
++ + ++PL VT D P+ LA ++V D +++ W + + +
Sbjct: 1612 VYAQNPSGESQPLVQTAVTNIDRPK--GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSP 1669
Query: 1385 NKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEASTAKEPEIGNL 1444
G ++ GL + Y VS+ + + L STA P +L
Sbjct: 1670 EDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTA-IPAPTDL 1728
Query: 1445 NVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTAHISGLPPSTDF 1504
+ +TP S + W + + + + + E N++ + +SGL +T +
Sbjct: 1729 KFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKY 1788
Query: 1505 IVYLSGLAPSIRTKTISATATTEALPLLENLT------ISDINPYGFTVSWMASENAFDS 1558
V + L ++ ++ TT LEN++ ++D T+SW
Sbjct: 1789 EVSVYALKDTLTSRPAQGVVTT-----LENVSPPRRARVTDATETTITISWRTKTETITG 1843
Query: 1559 FLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFTQGHQTKPLRAEIVTE 1618
F V V + P + T+ R + GL G Y++ + ++ P +V +
Sbjct: 1844 FQVDAVPANG-QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP----VVID 1898
Query: 1619 AEPEVD---NLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQSEPLEITLLAPERTR 1675
A +D NL TP+ +SW +++K K S P E+
Sbjct: 1899 ASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYE--KPGSPPREVVPRPRPGVT 1956
Query: 1676 D--ITGLREATEYEIELYGISKGRRSQTVSAIATTAMGSP 1713
+ ITGL TEY I + + ++S+ + T +P
Sbjct: 1957 EATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTP 1996
Score = 270 bits (689), Expect = 2e-71
Identities = 277/1182 (23%), Positives = 475/1182 (40%), Gaps = 87/1182 (7%)
Query: 856 NQYSIGNLKPDTEYEVSLIS---------RRGDMS----SNPAKETFTTGLDAPRN-LRR 901
N Y+I LKP YE LIS R D + S P TG P + L
Sbjct: 664 NSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVA 723
Query: 902 VSQ-----TDNSITLEWRNGKAAIDSYRIKYAPISGGDHAE-VDVPKSQQATTKTTLTGL 955
S+ T +S + W + + +R++Y GD + +D+P + T + L
Sbjct: 724 TSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPST---ATSVNIPDL 780
Query: 956 RPGTEYGIGVSAVKEDKESNPA-TINAATELDTPKDLQVSETAETSLTLLWKTPLAKFDR 1014
PG +Y + V + ED E + + + T D P D V + +TS+ + W P A
Sbjct: 781 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
Query: 1015 YRLNYSLPT-GQWVGVQLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKAST-- 1071
YR+ YS G + LP S L L+PG +YN+ + A + +S P ++ T
Sbjct: 841 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
Query: 1072 ----EQAPELENLTVTEVGWDGLRLNWTAADQAYEHFIIQVQEANKV-EAARNLTVPGSL 1126
+ P +L EV + + WT + A + + V N E + L + +
Sbjct: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
Query: 1127 RAVDIPGLKAATPYTVSIYGVIQGYRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWT 1186
A ++ GL Y ++ V G + L+A+ +T V E L + WT
Sbjct: 961 FA-EVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVL-VRWT 1018
Query: 1187 APEGAYEYFFIQVQEADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTP 1246
P + + V + Q P + L L+ A+ YT+++ + + +P
Sbjct: 1019 PPRAQITGYRLTVGLTRRGQPRQYNVGPS-VSKYPLRNLQPASEYTVSLVAIKGN-QESP 1076
Query: 1247 LSVEVLTEEVPDMGNLTV-TEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVP 1305
+ V T P TEV+ + + WT F + V+ + E +T
Sbjct: 1077 KATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI--GFKLGVRPSQGGEAPREVTSD 1134
Query: 1306 GSLRSMEIPGLRAGTPYTVTLHGEVRGHST-RPLAVEVVTEDLPQLG-------DLAVSE 1357
S+ + GL G Y T+ G P+ +VVT P D V
Sbjct: 1135 SG--SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLT 1192
Query: 1358 VGWD--------GLRLNWTAADNAYEHFVIQVQEVNKVEAA-QNLTLPGSLRAVDIPGLE 1408
V W+ G R+ T + + + +V ++ NL+ PGLE
Sbjct: 1193 VSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLS----------PGLE 1242
Query: 1409 AATPYRVSIYGVIRGYRTPVLSAEASTAKEPEIGNLNVSDITPESFNLSWMATDGIFET- 1467
Y VS+Y ++ + V ++ P +L ++I P++ ++W I T
Sbjct: 1243 ----YNVSVY-TVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTN 1297
Query: 1468 FTIEIIDSNRLLETVEYNISGAERTAHISGLPPSTDFIVYLSGLAPSIRTKTISATATTE 1527
F + + E +IS ++ ++ L P T+++V +S + + + T
Sbjct: 1298 FLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT- 1356
Query: 1528 ALPLLENLTISDINPYGFTVSWMASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELR 1587
L + SDI FTV W+A + + P+E + ++ + L
Sbjct: 1357 GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLT 1416
Query: 1588 GLITGIGYEVMVSGFTQGHQTKPLRAEIVTEAEPEVDNLLVSDATPDGFRLSWTADEGVF 1647
L G Y V + G + PL + +L V ATP +SW A
Sbjct: 1417 NLTPGTEYVVSIVALN-GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTV 1475
Query: 1648 DNFVLKIRDTKKQSEPLEITLLAPERTRDITGLREATEYEIELYGISKGR-----RSQTV 1702
+ + +T S E T+ + T I+GL+ +Y I +Y ++ GR S+ +
Sbjct: 1476 RYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVT-GRGDSPASSKPI 1534
Query: 1703 SAIATTAMGSPKEVIFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSMVTVDGT-K 1761
S T + P ++ +D+ +NS +V W ++ V +R+T P G P+ G +
Sbjct: 1535 SINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1594
Query: 1762 TQTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTTALDGPSGLVTANITDSEALARWQP 1821
T+ + L P VEY+VS+ A ES+P+ + T +D P GL ++ W+
Sbjct: 1595 TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWES 1654
Query: 1822 AIATVDSYVISYTGEK--VPEITRTVSGNTVEYALTDLEPATEYTLRIFAEKGPQKSSTI 1879
V Y ++Y+ + + E+ G L L P +EYT+ + A +S +
Sbjct: 1655 PQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPL 1714
Query: 1880 TAKFTTDLDSPRDLTATEVQSETALLTWRPPRASVTGYLL--VYESVDGTVKEVIVGPDT 1937
+T + +P DL T+V + W PP +TGY + + G +KE+ + PD+
Sbjct: 1715 IGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDS 1774
Query: 1938 TSYSLADLSPSTHYTAKIQALNGPLRSNMIQTIFTTIGLLYP 1979
+S ++ L +T Y + AL L S Q + TT+ + P
Sbjct: 1775 SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSP 1816
Score = 208 bits (530), Expect = 4e-53
Identities = 186/811 (22%), Positives = 334/811 (41%), Gaps = 56/811 (6%)
Query: 617 GEDCSEVSPPKDLVVTEVTEETVNLAW-DNEMRVTEYLVVYTPTHEGGLEMQFRVPGDQT 675
G + + P + +++T + + W +T Y + + P H G + RVP +
Sbjct: 1352 GRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRN 1411
Query: 676 STIIQELEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPL 735
S + L PG EY + + A+ ++S + + +T P L+ + TS+ + WD
Sbjct: 1412 SITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP 1471
Query: 736 DIAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNNTRGPGL 795
+ + I + + ++ +++ +GL PG +Y I+++ V P
Sbjct: 1472 AVTVRYYRITYGETGGNSPVQ-EFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPAS 1530
Query: 796 KRVTT----TRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDL 851
+ + T +D PSQ++V DV D + + W + + G +T K+ PG T
Sbjct: 1531 SKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTA 1590
Query: 852 TEDENQYSIGNLKPDTEYEVSLISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSITL 911
D+ + +I L+P EY VS+ ++ S P +T T +D P+ L +SI +
Sbjct: 1591 GPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKI 1650
Query: 912 EWRNGKAAIDSYRIKYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKED 971
W + + + YR+ Y+ G H P ++ T + L GLRPG+EY + V A+ +D
Sbjct: 1651 AWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAE--LQGLRPGSEYTVSVVALHDD 1708
Query: 972 KESNPATINAATELDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYS--LPTGQWVGV 1029
ES P +T + P DL+ ++ TSL+ W P + YR+ + TG +
Sbjct: 1709 MESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEI 1768
Query: 1030 QLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPAR-VKASTEQAPELENLTVTEVGWD 1088
L +++S V+ GL +Y V + A K S+PA+ V + E VT+
Sbjct: 1769 NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATET 1828
Query: 1089 GLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVI 1148
+ ++W + F + AN + T+ +R+ I GL+ T Y + +Y +
Sbjct: 1829 TITISWRTKTETITGFQVDAVPANG-QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1887
Query: 1149 QGYRTPVLSAEASTG-ETP-NLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEADTVE 1206
R+ + +AST + P NL + ++L ++W P + I+ ++ +
Sbjct: 1888 DNARSSPVVIDASTAIDAPSNLRFLATTP---NSLLVSWQPPRARITGYIIKYEKPGSPP 1944
Query: 1207 AAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLTEEVPDMGNLTVTE 1266
G+ + GL+ T YTI + + + + PL T + VT
Sbjct: 1945 REVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPF----VTH 2000
Query: 1267 VSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTVTL 1326
+D N GT Q Q+ + E H G R TP T
Sbjct: 2001 PGYDT--GNGIQLPGTSGQQPSVGQQ--MIFEEH--------------GFRRTTPPTTAT 2042
Query: 1327 HGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQVQEVNK 1386
+R H RP P +G A+S+ ++W + E ++I V
Sbjct: 2043 --PIR-HRPRPYP--------PNVGQEALSQT-----TISWAPFQDTSE-YIISCHPVGT 2085
Query: 1387 VEAAQNLTLPGSLRAVDIPGLEAATPYRVSI 1417
E +PG+ + + GL Y + +
Sbjct: 2086 DEEPLQFRVPGTSTSATLTGLTRGATYNIIV 2116
Score = 207 bits (526), Expect = 1e-52
Identities = 169/678 (24%), Positives = 290/678 (42%), Gaps = 71/678 (10%)
Query: 621 SEVSPPKDLVVTEVTEETVNLAW-DNEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTII 679
+E+ P + VT+V + ++++ W + VT Y V TP + G DQT I
Sbjct: 1540 TEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTI 1599
Query: 680 QELEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPLDIAF 739
+ L+P VEY + V+A + +S P+ T + P+GL F + S+++ W+
Sbjct: 1600 EGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQV 1659
Query: 740 ETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNNTRGPGLKRVT 799
+ + + + ++ E+ + E + GL PG EY +S+ + ++ L
Sbjct: 1660 SRYRVTYSSP-EDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQ 1718
Query: 800 TTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQYS 859
+T + AP+ ++ VT T+ W P ++ G + K+ G I+L D +
Sbjct: 1719 STAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVV 1778
Query: 860 IGNLKPDTEYEVSLISRRGDMSSNPAKETFTT--GLDAPRNLRRVSQTDNSITLEWRNGK 917
+ L T+YEVS+ + + ++S PA+ TT + PR R T+ +IT+ WR
Sbjct: 1779 VSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT 1838
Query: 918 AAIDSYRIKYAPISGGDHAEVDVPKSQQATTKT-TLTGLRPGTEYGIGVSAVKEDKESNP 976
I +++ P +G + + ++ + ++ T+TGL+PGT+Y I + + ++ S+P
Sbjct: 1839 ETITGFQVDAVPANG----QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP 1894
Query: 977 ATINAATELDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYSLPTGQWVGVQLPR--- 1033
I+A+T +D P +L+ T SL + W+ P A+ Y + Y P G +PR
Sbjct: 1895 VVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKP-GSPPREVVPRPRP 1953
Query: 1034 NTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTEQAPELENLTVTEVGWD---GL 1090
T + GLEPG EY + + A K KS+P + T Q VT G+D G+
Sbjct: 1954 GVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPF----VTHPGYDTGNGI 2009
Query: 1091 RLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVIQG 1150
+L T+ Q G + G + TP T +
Sbjct: 2010 QLPGTSGQQPSV---------------------GQQMIFEEHGFRRTTPPTTA------- 2041
Query: 1151 YRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEADTVEAAQN 1210
TP+ PN+G+ +++ ++W + EY I T E
Sbjct: 2042 --TPI--RHRPRPYPPNVGQEALSQT-----TISWAPFQDTSEYI-ISCHPVGTDEEPLQ 2091
Query: 1211 LTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLTEEVPDMGNLTVTEVSWD 1270
VPG S L GL Y I + + + EEV +GN +V E
Sbjct: 2092 FRVPGTSTSATLTGLTRGATYNIIVEALKDQ------QRHKVREEVVTVGN-SVNE---- 2140
Query: 1271 ALRLNWTTPDGTYDQFTI 1288
LN T D +D +T+
Sbjct: 2141 --GLNQPTDDSCFDPYTV 2156
Score = 153 bits (386), Expect = 2e-36
Identities = 147/662 (22%), Positives = 264/662 (39%), Gaps = 40/662 (6%)
Query: 1365 LNWTAADNAY-EHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIR- 1422
+ W A ++ ++++ + N V + T+PG L + I GL+ Y + + +
Sbjct: 628 IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687
Query: 1423 GYR-------------TPVLSAEASTAKEP----EIGNLNVSDITPESFNLSWMATDGIF 1465
G++ TPV S + P + +V++IT SF +SW++
Sbjct: 688 GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747
Query: 1466 ETFTIEIIDSNRLLETVEYNISGAERTAHISGLPPSTDFIVYLSGLAPSIRTKTISATAT 1525
F +E S E ++ + +I L P +IV + ++ I +T+
Sbjct: 748 SGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQ 807
Query: 1526 TEALPLLENLTISDINPYGFTVSWMASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLE 1585
T A + T+ ++ V W + + + S + E L T +
Sbjct: 808 TTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEG-SSTELNLPETANSVT 866
Query: 1586 LRGLITGIGYEVMVSGFTQGHQTKPLRAEIVTEAEPEVD------NLLVSDATPDGFRLS 1639
L L G+ Y + + + ++ P+ + T P D +L + T +
Sbjct: 867 LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926
Query: 1640 WTADEGVFDNFVLKIRDTKKQSEPLEITLLAPERTRDITGLREATEYEIELYGISKGRRS 1699
WT E + + + E + ++ ++TGL Y +++ +S GR S
Sbjct: 927 WTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986
Query: 1700 QTVSAIATTAMGSPKEVIFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSMVTVDG 1759
+ ++A TT + +P + F + T+++ V W P AQ+ +R+T G P V
Sbjct: 987 KPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGP 1046
Query: 1760 TKTQTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTTALDGPS-GLVTANITDSEALAR 1818
+ ++ L L P EY VS++A+KG +ES +G FTT G S +T++ +
Sbjct: 1047 SVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVIT 1106
Query: 1819 WQPAIATVDSYVISYTGEKVPEITRTVSGNTVEYALTDLEPATEYTLRI-FAEKGPQKSS 1877
W PA + + + E R V+ ++ ++ L P EY I G ++ +
Sbjct: 1107 WTPAPRI--GFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDA 1164
Query: 1878 TITAKFTTDLDSPRDLTATEVQSETALLT--W-RPPRASVTGYLLVYESVD---GTVKEV 1931
I K T L P +L E +T +LT W R +TGY + + G E
Sbjct: 1165 PIVNKVVTPLSPPTNL-HLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEE 1223
Query: 1932 IVGPDTTSYSLADLSPSTHYTAKIQALNGPLRSNMIQTIFTTIGLLYPFPKDCSQAMLNG 1991
+V D +S + +LSP Y + + S I TI P P D +
Sbjct: 1224 VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKES---VPISDTIIPAVPPPTDLRFTNIGP 1280
Query: 1992 DT 1993
DT
Sbjct: 1281 DT 1282
>gi|47132553 fibronectin 1 isoform 5 preproprotein [Homo sapiens]
Length = 2296
Score = 358 bits (920), Expect = 2e-98
Identities = 321/1314 (24%), Positives = 549/1314 (41%), Gaps = 71/1314 (5%)
Query: 624 SPPKDLVVTEVTEETVN--LAWD--NEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTII 679
S P ++ +TE + + + W+ +++Y++ + P + G + +PG S I
Sbjct: 609 SGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTI 668
Query: 680 QELEPGVEYFIRVFAILE-------------NKKSIPVSARVATYLPAP------EGLKF 720
+ L+PGV Y ++ +I + S PV++ T P
Sbjct: 669 KGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESV 728
Query: 721 KSIKETSVEVEWDPLDIAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYE 780
I +S V W + + + + DE + L TS L PG++Y
Sbjct: 729 TEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYL-DLPSTATSVNIPDLLPGRKYI 787
Query: 781 ISLH-IVKNNTRGPGLKRVTTTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGI 839
++++ I ++ + L TT DAP V V DT+ ++ W +P A I G + Y
Sbjct: 788 VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYS- 846
Query: 840 KDVPGDRTTIDLTEDENQYSIGNLKPDTEYEVSLISRRGDMSSNPAK-ETFTTG------ 892
V G T ++L E N ++ +L+P +Y +++ + + S P + TTG
Sbjct: 847 PSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDT 906
Query: 893 LDAPRNLRRVSQTDNSITLEWRNGKAAIDSYRIKYAPIS-GGDHAEVDVPKSQQATTKTT 951
+ +PR+L+ V TD +T+ W ++A+ YR+ P++ G+H + +P S+ T
Sbjct: 907 VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQ-RLPISRN--TFAE 963
Query: 952 LTGLRPGTEYGIGVSAVKEDKESNPATINAATELDTPKDLQVSETAETSLTLLWKTPLAK 1011
+TGL PG Y V AV +ES P T T+LD P +LQ ++++ + W P A+
Sbjct: 964 VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQ 1023
Query: 1012 FDRYRLNYSLPT-GQWVGVQLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKAS 1070
YRL L GQ + + + Y LR L+P EY V L A KG +S A +
Sbjct: 1024 ITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFT 1083
Query: 1071 TEQAPELENLTVTEVGWDGLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVD 1130
T Q TEV + + WT A + F + V+ + EA R +T ++
Sbjct: 1084 TLQPGSSIPPYNTEVTETTIVITWTPAPRI--GFKLGVRPSQGGEAPREVTSDSG--SIV 1139
Query: 1131 IPGLKAATPYTVSIYGVIQGYR--TPVLSAEASTGETPNLGEVVVAEVGWDALKLNW--- 1185
+ GL Y +I + G P+++ + T +P + A L ++W
Sbjct: 1140 VSGLTPGVEYVYTIQVLRDGQERDAPIVN-KVVTPLSPPTNLHLEANPDTGVLTVSWERS 1198
Query: 1186 TAPE-GAYEYFFIQV--QEADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDF 1242
T P+ Y Q+ +++E V S L Y +++ V D
Sbjct: 1199 TTPDITGYRITTTPTNGQQGNSLEEV----VHADQSSCTFDNLSPGLEYNVSVYTVKDDK 1254
Query: 1243 STTPLSVEVLTEEVPDMGNLTVTEVSWDALRLNWTTPDGT-YDQFTIQVQEADQVEEAHN 1301
+ P+S + + VP +L T + D +R+ W P F ++ E+
Sbjct: 1255 ESVPIS-DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE 1313
Query: 1302 LTVPGSLRSMEIPGLRAGTPYTVTLHGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWD 1361
L++ S ++ + L GT Y V++ H + PL T L + S++ +
Sbjct: 1314 LSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFSDITAN 1372
Query: 1362 GLRLNWTAADNAYEHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVI 1421
++W A + I+ + + +P S ++ + L T Y VSI +
Sbjct: 1373 SFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN 1432
Query: 1422 RGYRTPVLSAEASTAKEPEIGNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLET 1481
+P+L + ST + +L V TP S +SW A + I ++
Sbjct: 1433 GREESPLLIGQQSTVSDVP-RDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPV 1491
Query: 1482 VEYNISGAERTAHISGLPPSTDFIVYL-----SGLAPSIRTKTISATATTEALPLLENLT 1536
E+ + G++ TA ISGL P D+ + + G +P+ +K IS TE + +
Sbjct: 1492 QEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPA-SSKPISINYRTE-IDKPSQMQ 1549
Query: 1537 ISDINPYGFTVSWMASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYE 1596
++D+ +V W+ S + + VT + T Q ++ + GL + Y
Sbjct: 1550 VTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYV 1609
Query: 1597 VMVSGFTQGHQTKPLRAEIVTEAEPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRD 1656
V V +++PL VT P +L + TP WT + +++
Sbjct: 1610 VSVYAQNPSGESQPLVQTAVTTI-PAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTP 1668
Query: 1657 TKKQSEPLEITLLAPERTRDITGLREATEYEIELYGISKGRRSQTVSAIATTA--MGSPK 1714
+K EI L + ++GL AT+YE+ +Y + S+ + TT + P+
Sbjct: 1669 KEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPR 1728
Query: 1715 EVIFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSMVTVDGTKTQTRLVKLIPGVE 1774
+D TE + T+SWR T + F++ VP G TP T+ + L PG +
Sbjct: 1729 RARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTD 1788
Query: 1775 YLVSIIAMKGFEESEPVSGSFTTALDGPSGLVTANITDSEALARWQPAIATVDSYVISY- 1833
Y + + + S PV +TA+D PS L T + L WQP A + Y+I Y
Sbjct: 1789 YKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYE 1848
Query: 1834 -TGEKVPEITRTVSGNTVEYALTDLEPATEYTLRIFAEKGPQKSSTITAKFTTD 1886
G E+ E +T LEP TEYT+ + A K QKS + + TD
Sbjct: 1849 KPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTD 1902
Score = 308 bits (788), Expect = 5e-83
Identities = 299/1259 (23%), Positives = 523/1259 (41%), Gaps = 92/1259 (7%)
Query: 767 SYRQTGLAPGQEYEISLHIVKN--------------NTRGPGLKRVTTTRLDAPSQI--- 809
SY GL PG YE L ++ +T P T S +
Sbjct: 665 SYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVAT 724
Query: 810 --EVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQYSIGNLKPDT 867
V ++T ++ +++W + G + Y + + + +DL +I +L P
Sbjct: 725 SESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGR 784
Query: 868 EYEVSL--ISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSITLEWRNGKAAIDSYRI 925
+Y V++ IS G+ S + TT DAP + D SI + W +A I YRI
Sbjct: 785 KYIVNVYQISEDGEQSLILSTSQ-TTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRI 843
Query: 926 KYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKEDKESNPATINAATE- 984
Y+P G E+++P++ + T L+ L+PG +Y I + AV+E++ES P I T
Sbjct: 844 VYSPSVEGSSTELNLPETANSVT---LSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
Query: 985 ------LDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNY---SLPTGQWVGVQLPRNT 1035
+ +P+DLQ E + +T++W P + YR++ +LP + + RNT
Sbjct: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
Query: 1036 TSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTE-QAPELENLTVTEVGWDGLRLNW 1094
+ V GL PG Y + A +SKP + +T+ AP NL + + W
Sbjct: 961 FAEVT-GLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPT--NLQFVNETDSTVLVRW 1017
Query: 1095 TAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVIQGYRTP 1154
T + + V + + R V S+ + L+ A+ YTVS+ + +P
Sbjct: 1018 TPPRAQITGYRLTVGLTRRGQP-RQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESP 1076
Query: 1155 VLSAEASTGETPNLGEVVVAEVGWDALKLNWT-APEGAYEYFFIQVQEADTVEAAQNLTV 1213
+ +T + + EV + + WT AP ++ + V+ + EA + +T
Sbjct: 1077 KATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFK---LGVRPSQGGEAPREVTS 1133
Query: 1214 PGGLRSTDLPGLKAATHYTITIR----GVTQDFS-----TTPLS--VEVLTEEVPDMGNL 1262
G S + GL Y TI+ G +D TPLS + E PD G L
Sbjct: 1134 DSG--SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVL 1191
Query: 1263 TVTEVSWDALRLNWTTPDGTYDQFTIQV---QEADQVEEAHNLTVPGSLRSMEIPGLRAG 1319
TV SW+ TTPD T + T Q+ + +EE V S L G
Sbjct: 1192 TV---SWERS----TTPDITGYRITTTPTNGQQGNSLEEV----VHADQSSCTFDNLSPG 1240
Query: 1320 TPYTVTLHGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWDGLRLNWTAADNA-YEHFV 1378
Y V+++ + P++ + + +P DL + +G D +R+ W + +F+
Sbjct: 1241 LEYNVSVYTVKDDKESVPIS-DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFL 1299
Query: 1379 IQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEASTAKE 1438
++ V E L++ S AV + L T Y VS+ V + + L T +
Sbjct: 1300 VRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD 1359
Query: 1439 PEIGNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTAHISGL 1498
G ++ SDIT SF + W+A + I + E + + + ++ L
Sbjct: 1360 SPTG-IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNL 1418
Query: 1499 PPSTDFIVYLSGLAPSIRTKT-ISATATTEALPLLENLTISDINPYGFTVSWMASENAFD 1557
P T+++V + L + I +T +P +L + P +SW A
Sbjct: 1419 TPGTEYVVSIVALNGREESPLLIGQQSTVSDVP--RDLEVVAATPTSLLISWDAPAVTVR 1476
Query: 1558 SFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFT----QGHQTKPLRA 1613
+ +T ++G QEFT+ G++ + GL G+ Y + V T +KP+
Sbjct: 1477 YYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISI 1536
Query: 1614 EIVTEAEPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQSE-PLEITLLAPE 1672
TE + + + V+D + + W + ++ T K P + P+
Sbjct: 1537 NYRTEID-KPSQMQVTDVQDNSISVKWLPSSSPVTGY--RVTTTPKNGPGPTKTKTAGPD 1593
Query: 1673 RTR-DITGLREATEYEIELYGISKGRRSQTVSAIATTAMGSPKEVIFSDITENSATVSWR 1731
+T I GL+ EY + +Y + SQ + A T + +P ++ F+ +T S + W
Sbjct: 1594 QTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWT 1653
Query: 1732 APTAQVESFRITYVPITGGTPSM-VTVDGTKTQTRLVKLIPGVEYLVSIIAMKGFEESEP 1790
P Q+ +R+ P P + + + + L+ +Y VS+ A+K S P
Sbjct: 1654 PPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRP 1713
Query: 1791 VSGSFTTA--LDGPSGLVTANITDSEALARWQPAIATVDSYVI-SYTGEKVPEITRTVSG 1847
G TT + P + T++ W+ T+ + + + I RT+
Sbjct: 1714 AQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKP 1773
Query: 1848 NTVEYALTDLEPATEYTLRIFAEKGPQKSSTITAKFTTDLDSPRDLTATEVQSETALLTW 1907
+ Y +T L+P T+Y + ++ +SS + +T +D+P +L + L++W
Sbjct: 1774 DVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSW 1833
Query: 1908 RPPRASVTGYLLVYESVDGTVKEVI--VGPDTTSYSLADLSPSTHYTAKIQALNGPLRS 1964
+PPRA +TGY++ YE +EV+ P T ++ L P T YT + AL +S
Sbjct: 1834 QPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKS 1892
Score = 272 bits (695), Expect = 3e-72
Identities = 300/1234 (24%), Positives = 480/1234 (38%), Gaps = 81/1234 (6%)
Query: 623 VSPPKDLVVTEVTEETVNLAW-DNEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTIIQE 681
V P+DL EVT+ V + W E VT Y V P + G Q T +
Sbjct: 907 VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTG 966
Query: 682 LEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPLDIAFET 741
L PGV Y+ +VFA+ ++S P++A+ T L AP L+F + +++V V W P
Sbjct: 967 LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITG 1026
Query: 742 WEIIFRNMNKEDEGEITKSLRRPETS-YRQTGLAPGQEYEISLHIVKNNTRGPGLKRVTT 800
+ + + G+ + P S Y L P EY +SL +K N P V T
Sbjct: 1027 YRL---TVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFT 1083
Query: 801 TRLDAPSQIEV--KDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQY 858
T L S I +VT+TT +ITW P I G +L G++ G ++T D
Sbjct: 1084 T-LQPGSSIPPYNTEVTETTIVITW-TPAPRI-GFKL--GVRPSQGGEAPREVTSDSGSI 1138
Query: 859 SIGNLKPDTEYEVSL-ISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSI-TLEW-RN 915
+ L P EY ++ + R G P T L P NL + D + T+ W R+
Sbjct: 1139 VVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERS 1198
Query: 916 GKAAIDSYRIKYAPISG--GDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKEDKE 973
I YRI P +G G+ E V Q + T L PG EY + V VK+DKE
Sbjct: 1199 TTPDITGYRITTTPTNGQQGNSLEEVVHADQ---SSCTFDNLSPGLEYNVSVYTVKDDKE 1255
Query: 974 SNPATINAATELDTPKDLQVSETAETSLTLLWKTPLA-KFDRYRLNYSLPTGQ--WVGVQ 1030
S P + + P DL+ + ++ + W P + + + YS + +
Sbjct: 1256 SVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELS 1315
Query: 1031 LPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTEQAPELENLTVTEVGWDGL 1090
+ + + VL L PG EY V +++ +H+S P R + T + +++ +
Sbjct: 1316 ISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFSDITANSF 1374
Query: 1091 RLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVIQG 1150
++W A + I+ + R VP S ++ + L T Y VSI +
Sbjct: 1375 TVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR 1434
Query: 1151 YRTPVLSAEAST-GETPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEADTVEAAQ 1209
+P+L + ST + P EVV A +L ++W AP Y+ I E Q
Sbjct: 1435 EESPLLIGQQSTVSDVPRDLEVVAATP--TSLLISWDAPAVTVRYYRITYGETGGNSPVQ 1492
Query: 1210 NLTVPGGLRSTDLPGLKAATHYTITIRGVT----QDFSTTPLSVEVLTEEVPDMGNLTVT 1265
TVPG + + GLK YTIT+ VT S+ P+S+ T E+ + VT
Sbjct: 1493 EFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRT-EIDKPSQMQVT 1551
Query: 1266 EVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTVT 1325
+V +++ + W + + + T M I GL+ Y V+
Sbjct: 1552 DVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVS 1611
Query: 1326 LHGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQVQEVN 1385
++ + ++PL VT +P DL ++V L WT + + ++V
Sbjct: 1612 VYAQNPSGESQPLVQTAVT-TIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKE 1670
Query: 1386 KVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRT-PVLSAEASTAKEPEIGNL 1444
K + + L +V + GL AT Y VS+Y + + P +
Sbjct: 1671 KTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRA 1730
Query: 1445 NVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTAHISGLPPSTDF 1504
V+D T + +SW F ++ + +N ++ I R+ I+GL P TD+
Sbjct: 1731 RVTDATETTITISWRTKTETITGFQVDAVPANG-QTPIQRTIKPDVRSYTITGLQPGTDY 1789
Query: 1505 IVYLSGLAPSIRTKTISATATTEALPLLENLTISDINPYGFTVSWMASENAFDSFLVTVV 1564
+YL L + R+ + A+T A+ NL P VSW +++
Sbjct: 1790 KIYLYTLNDNARSSPVVIDAST-AIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYE 1848
Query: 1565 DSGKLLDPQEFTLSGTQRKLE--LRGLITGIGYEVMVSGFTQGHQTKPL--------RAE 1614
G P+E E + GL G Y + V +++PL +
Sbjct: 1849 KPGS--PPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQ 1906
Query: 1615 IVTEAEPEVDNLLVSDA----------------TPDGFRLSWTADE--GVFDNFVLKIRD 1656
+VT P + + D T +G +L T+ + V + +
Sbjct: 1907 LVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHG 1966
Query: 1657 TKKQSEPLEITLLAPERTRDITGLREATEYEIELYGISKGRRSQTVSAIATTAMGSPKEV 1716
++ + P T P R R E EI++ I R + G
Sbjct: 1967 FRRTTPP---TTATPIRHRPRPYPPNVGE-EIQIGHIP---REDVDYHLYPHGPGLNPNA 2019
Query: 1717 IFSDITENSATVSWRAPTAQVESFRITYVPI-TGGTPSMVTVDGTKTQTRLVKLIPGVEY 1775
+ T+SW AP + I+ P+ T P V GT T L L G Y
Sbjct: 2020 STGQEALSQTTISW-APFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATY 2078
Query: 1776 LVSIIAMKG------FEESEPVSGSFTTALDGPS 1803
+ + A+K EE V S L+ P+
Sbjct: 2079 NIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPT 2112
Score = 252 bits (644), Expect = 2e-66
Identities = 272/1173 (23%), Positives = 470/1173 (40%), Gaps = 92/1173 (7%)
Query: 856 NQYSIGNLKPDTEYEVSLIS---------RRGDMS----SNPAKETFTTGLDAPRN-LRR 901
N Y+I LKP YE LIS R D + S P TG P + L
Sbjct: 664 NSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVA 723
Query: 902 VSQ-----TDNSITLEWRNGKAAIDSYRIKYAPISGGDHAE-VDVPKSQQATTKTTLTGL 955
S+ T +S + W + + +R++Y GD + +D+P + T + L
Sbjct: 724 TSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPST---ATSVNIPDL 780
Query: 956 RPGTEYGIGVSAVKEDKESNPA-TINAATELDTPKDLQVSETAETSLTLLWKTPLAKFDR 1014
PG +Y + V + ED E + + + T D P D V + +TS+ + W P A
Sbjct: 781 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
Query: 1015 YRLNYSLPT-GQWVGVQLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKAST-- 1071
YR+ YS G + LP S L L+PG +YN+ + A + +S P ++ T
Sbjct: 841 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
Query: 1072 ----EQAPELENLTVTEVGWDGLRLNWTAADQAYEHFIIQVQEANKV-EAARNLTVPGSL 1126
+ P +L EV + + WT + A + + V N E + L + +
Sbjct: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
Query: 1127 RAVDIPGLKAATPYTVSIYGVIQGYRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWT 1186
A ++ GL Y ++ V G + L+A+ +T V E L + WT
Sbjct: 961 FA-EVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVL-VRWT 1018
Query: 1187 APEGAYEYFFIQVQEADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTP 1246
P + + V + Q P + L L+ A+ YT+++ + + +P
Sbjct: 1019 PPRAQITGYRLTVGLTRRGQPRQYNVGPS-VSKYPLRNLQPASEYTVSLVAIKGN-QESP 1076
Query: 1247 LSVEVLTEEVPDMGNLTV-TEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVP 1305
+ V T P TEV+ + + WT F + V+ + E +T
Sbjct: 1077 KATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI--GFKLGVRPSQGGEAPREVTSD 1134
Query: 1306 GSLRSMEIPGLRAGTPYTVTLHGEVRGHST-RPLAVEVVTEDLPQLG-------DLAVSE 1357
S+ + GL G Y T+ G P+ +VVT P D V
Sbjct: 1135 SG--SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLT 1192
Query: 1358 VGWD--------GLRLNWTAADNAYEHFVIQVQEVNKVEAA-QNLTLPGSLRAVDIPGLE 1408
V W+ G R+ T + + + +V ++ NL+ PGLE
Sbjct: 1193 VSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLS----------PGLE 1242
Query: 1409 AATPYRVSIYGVIRGYRTPVLSAEASTAKEPEIGNLNVSDITPESFNLSWMATDGIFET- 1467
Y VS+Y ++ + V ++ P +L ++I P++ ++W I T
Sbjct: 1243 ----YNVSVY-TVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTN 1297
Query: 1468 FTIEIIDSNRLLETVEYNISGAERTAHISGLPPSTDFIVYLSGLAPSIRTKTISATATTE 1527
F + + E +IS ++ ++ L P T+++V +S + + + T
Sbjct: 1298 FLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT- 1356
Query: 1528 ALPLLENLTISDINPYGFTVSWMASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELR 1587
L + SDI FTV W+A + + P+E + ++ + L
Sbjct: 1357 GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLT 1416
Query: 1588 GLITGIGYEVMVSGFTQGHQTKPLRAEIVTEAEPEVDNLLVSDATPDGFRLSWTADEGVF 1647
L G Y V + G + PL + +L V ATP +SW A
Sbjct: 1417 NLTPGTEYVVSIVALN-GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTV 1475
Query: 1648 DNFVLKIRDTKKQSEPLEITLLAPERTRDITGLREATEYEIELYGISKGR-----RSQTV 1702
+ + +T S E T+ + T I+GL+ +Y I +Y ++ GR S+ +
Sbjct: 1476 RYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVT-GRGDSPASSKPI 1534
Query: 1703 SAIATTAMGSPKEVIFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSMVTVDGT-K 1761
S T + P ++ +D+ +NS +V W ++ V +R+T P G P+ G +
Sbjct: 1535 SINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1594
Query: 1762 TQTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTTALDGPSGLVTANITDSEALARWQP 1821
T+ + L P VEY+VS+ A ES+P+ + T + P+ L +T + A+W P
Sbjct: 1595 TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTP 1654
Query: 1822 AIATVDSYVISYTGEK----VPEITRTVSGNTVEYALTDLEPATEYTLRIFAEKGPQKSS 1877
+ Y + T ++ + EI ++V ++ L AT+Y + ++A K S
Sbjct: 1655 PNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSV--VVSGLMVATKYEVSVYALKDTLTSR 1712
Query: 1878 TITAKFTT--DLDSPRDLTATEVQSETALLTWRPPRASVTGYLLVYESVDG-TVKEVIVG 1934
TT ++ PR T+ T ++WR ++TG+ + +G T + +
Sbjct: 1713 PAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIK 1772
Query: 1935 PDTTSYSLADLSPSTHYTAKIQALNGPLRSNMI 1967
PD SY++ L P T Y + LN RS+ +
Sbjct: 1773 PDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV 1805
Score = 229 bits (584), Expect = 2e-59
Identities = 252/1125 (22%), Positives = 465/1125 (41%), Gaps = 74/1125 (6%)
Query: 907 NSITLEWRNGKAA-IDSYRIKYAPISG-GDHAEVDVPKSQQATTKTTLTGLRPGTEYGIG 964
NS ++W + + I Y +++ P + G E +P + T + GL+PG Y
Sbjct: 624 NSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYT---IKGLKPGVVYEGQ 680
Query: 965 VSAVKE-------------DKESNPATINAATELDTP------KDLQVSETAETSLTLLW 1005
+ ++++ S P T N T TP V+E +S + W
Sbjct: 681 LISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSW 740
Query: 1006 KTPLAKFDRYRLNYSLPT--GQWVGVQLPRNTTSYVLRGLEPGQEY--NVLLTAEKGRHK 1061
+ +R+ Y L + + LP TS + L PG++Y NV +E G
Sbjct: 741 VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQS 800
Query: 1062 SKPARVKASTEQAPELENLTVTEVGWDGLRLNWTAADQAYEHFIIQVQEANKVEAARNLT 1121
+ + + AP + TV +V + + W+ + I V + ++ L
Sbjct: 801 LILSTSQTTAPDAPP--DPTVDQVDDTSIVVRWSRPQAPITGYRI-VYSPSVEGSSTELN 857
Query: 1122 VPGSLRAVDIPGLKAATPYTVSIYGVIQGYR-TPVLSAEASTGE-----TPNLGEVVVAE 1175
+P + +V + L+ Y ++IY V + TPV+ + +TG P+ ++ E
Sbjct: 858 LPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVE 917
Query: 1176 VGWDALKLNWTAPEGAYEYFFIQVQEADTV-EAAQNLTVPGGLRST--DLPGLKAATHYT 1232
V + + WT PE A + + V + E Q L + R+T ++ GL Y
Sbjct: 918 VTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPIS---RNTFAEVTGLSPGVTYY 974
Query: 1233 ITIRGVTQDFSTTPLSVEVLTE-EVPDMGNLTVTEVSWDALRLNWTTPDGTYDQFTIQVQ 1291
+ V+ + PL+ + T+ + P NL + + + WT P + + V
Sbjct: 975 FKVFAVSHGRESKPLTAQQTTKLDAPT--NLQFVNETDSTVLVRWTPPRAQITGYRLTVG 1032
Query: 1292 EADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTVTLHGEVRGHSTRPLAVEVVTEDLPQLG 1351
+ + V S+ + L+ + YTV+L ++G+ P A V T P
Sbjct: 1033 LTRR-GQPRQYNVGPSVSKYPLRNLQPASEYTVSLVA-IKGNQESPKATGVFTTLQPGSS 1090
Query: 1352 DLAVS-EVGWDGLRLNWTAADNAYEHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAA 1410
+ EV + + WT A F + V+ EA + +T ++ + GL
Sbjct: 1091 IPPYNTEVTETTIVITWTPAPRI--GFKLGVRPSQGGEAPREVTSDSG--SIVVSGLTPG 1146
Query: 1411 TPYRVSIYGVIRGYR--TPVLSAEASTAKEPEIGNLNVSDITPES--FNLSW-MATDGIF 1465
Y +I + G P+++ + P NL++ + P++ +SW +T
Sbjct: 1147 VEYVYTIQVLRDGQERDAPIVNKVVTPLSPPT--NLHL-EANPDTGVLTVSWERSTTPDI 1203
Query: 1466 ETFTIEIIDSN-RLLETVEYNISGAERTAHISGLPPSTDFIVYLSGLAPSIRTKTISATA 1524
+ I +N + ++E + + + L P ++ V + + + IS T
Sbjct: 1204 TGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTI 1263
Query: 1525 TTEALPLLENLTISDINPYGFTVSWMASENA-FDSFLVTVVDSGKLLDPQEFTLSGTQRK 1583
A+P +L ++I P V+W + +FLV D E ++S +
Sbjct: 1264 IP-AVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNA 1322
Query: 1584 LELRGLITGIGYEVMVSGFTQGHQTKPLRAEIVTEAEPEVDNLLVSDATPDGFRLSWTAD 1643
+ L L+ G Y V VS + H++ PLR T + + SD T + F + W A
Sbjct: 1323 VVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPT-GIDFSDITANSFTVHWIAP 1381
Query: 1644 EGVFDNFVLKIRDTKKQSEPLEITLLAPERTRDITGLREATEYEIELYGISKGRRSQTVS 1703
+ ++ P E + + +T L TEY + + ++ S +
Sbjct: 1382 RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLI 1441
Query: 1704 AIATTAMGSPKEVIFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSM-VTVDGTKT 1762
+T P+++ T S +SW AP V +RITY G +P TV G+K+
Sbjct: 1442 GQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKS 1501
Query: 1763 QTRLVKLIPGVEYLVSIIAMKGFEES----EPVSGSFTTALDGPSGLVTANITDSEALAR 1818
+ L PGV+Y +++ A+ G +S +P+S ++ T +D PS + ++ D+ +
Sbjct: 1502 TATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVK 1561
Query: 1819 WQPAIATVDSYVISYTGEKVPEITRTVSG--NTVEYALTDLEPATEYTLRIFAEKGPQKS 1876
W P+ + V Y ++ T + P T+T + + E + L+P EY + ++A+ +S
Sbjct: 1562 WLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGES 1621
Query: 1877 STITAKFTTDLDSPRDLTATEVQSETALLTWRPPRASVTGYLL--VYESVDGTVKEVIVG 1934
+ T + +P DL T+V + W PP +TGY + + G +KE+ +
Sbjct: 1622 QPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLA 1681
Query: 1935 PDTTSYSLADLSPSTHYTAKIQALNGPLRSNMIQTIFTTIGLLYP 1979
PD++S ++ L +T Y + AL L S Q + TT+ + P
Sbjct: 1682 PDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSP 1726
Score = 226 bits (576), Expect = 2e-58
Identities = 208/935 (22%), Positives = 382/935 (40%), Gaps = 29/935 (3%)
Query: 616 SGEDCSEVSPPKDLVVTEVTEETVNLAWDN-EMRVTEYLVVYTPTHEGGLEMQFRVPGDQ 674
+ + +++ P +L T+ TV + W ++T Y + T G Q+ V
Sbjct: 990 TAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQ-PRQYNVGPSV 1048
Query: 675 TSTIIQELEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFKS-IKETSVEVEWD 733
+ ++ L+P EY + + AI N++S + T P + + + ET++ + W
Sbjct: 1049 SKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWT 1108
Query: 734 PLD-IAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNNT-R 791
P I F+ + GE + + S +GL PG EY ++ ++++ R
Sbjct: 1109 PAPRIGFKL------GVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQER 1162
Query: 792 GPGLKRVTTTRLDAPSQIEVKDVTDTTAL-ITWFKPLA-EIDGIELTYG-IKDVPGDRTT 848
+ T L P+ + ++ DT L ++W + +I G +T G+
Sbjct: 1163 DAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLE 1222
Query: 849 IDLTEDENQYSIGNLKPDTEYEVSLISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNS 908
+ D++ + NL P EY VS+ + + D S P +T + P +LR + ++
Sbjct: 1223 EVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDT 1282
Query: 909 ITLEWRNGKAA-IDSYRIKYAPISGG-DHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVS 966
+ + W + + ++ ++Y+P+ D AE+ + S A LT L PGTEY + VS
Sbjct: 1283 MRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVV---LTNLLPGTEYVVSVS 1339
Query: 967 AVKEDKESNPATINAATELDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYSLP--TG 1024
+V E ES P T LD+P + S+ S T+ W P A YR+ + +G
Sbjct: 1340 SVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSG 1399
Query: 1025 QWVGVQLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTEQAPELENLTVTE 1084
+ ++P + S L L PG EY V + A GR +S P + + + +L V
Sbjct: 1400 RPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREES-PLLIGQQSTVSDVPRDLEVVA 1458
Query: 1085 VGWDGLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSI 1144
L ++W A ++ I E + TVPGS I GLK YT+++
Sbjct: 1459 ATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518
Query: 1145 YGVIQGYRTPVLSAEASTG---ETPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQE 1201
Y V +P S S E ++ V +V +++ + W + +
Sbjct: 1519 YAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTP 1578
Query: 1202 ADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLTEEVPDMGN 1261
+ + T + GL+ Y +++ + PL V+ +P +
Sbjct: 1579 KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL-VQTAVTTIPAPTD 1637
Query: 1262 LTVTEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTP 1321
L T+V+ +L WT P+ + ++V ++ + + S+ + GL T
Sbjct: 1638 LKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATK 1697
Query: 1322 YTVTLHGEVRGHSTRPLAVEVVT-EDLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQ 1380
Y V+++ ++RP V T E++ V++ + ++W F +
Sbjct: 1698 YEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVD 1757
Query: 1381 VQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEASTAKEPE 1440
N Q T+ +R+ I GL+ T Y++ +Y + R+ + +ASTA +
Sbjct: 1758 AVPANGQTPIQR-TIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAP 1816
Query: 1441 IGNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTAHISGLPP 1500
NL TP S +SW + I+ V A I+GL P
Sbjct: 1817 -SNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEP 1875
Query: 1501 STDFIVYLSGLAPSIRTKTISATATTEALPLLENL 1535
T++ +Y+ L + +++ + T+ LP L L
Sbjct: 1876 GTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTL 1910
Score = 153 bits (386), Expect = 2e-36
Identities = 147/662 (22%), Positives = 264/662 (39%), Gaps = 40/662 (6%)
Query: 1365 LNWTAADNAY-EHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIR- 1422
+ W A ++ ++++ + N V + T+PG L + I GL+ Y + + +
Sbjct: 628 IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687
Query: 1423 GYR-------------TPVLSAEASTAKEP----EIGNLNVSDITPESFNLSWMATDGIF 1465
G++ TPV S + P + +V++IT SF +SW++
Sbjct: 688 GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747
Query: 1466 ETFTIEIIDSNRLLETVEYNISGAERTAHISGLPPSTDFIVYLSGLAPSIRTKTISATAT 1525
F +E S E ++ + +I L P +IV + ++ I +T+
Sbjct: 748 SGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQ 807
Query: 1526 TEALPLLENLTISDINPYGFTVSWMASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLE 1585
T A + T+ ++ V W + + + S + E L T +
Sbjct: 808 TTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEG-SSTELNLPETANSVT 866
Query: 1586 LRGLITGIGYEVMVSGFTQGHQTKPLRAEIVTEAEPEVD------NLLVSDATPDGFRLS 1639
L L G+ Y + + + ++ P+ + T P D +L + T +
Sbjct: 867 LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926
Query: 1640 WTADEGVFDNFVLKIRDTKKQSEPLEITLLAPERTRDITGLREATEYEIELYGISKGRRS 1699
WT E + + + E + ++ ++TGL Y +++ +S GR S
Sbjct: 927 WTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986
Query: 1700 QTVSAIATTAMGSPKEVIFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSMVTVDG 1759
+ ++A TT + +P + F + T+++ V W P AQ+ +R+T G P V
Sbjct: 987 KPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGP 1046
Query: 1760 TKTQTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTTALDGPS-GLVTANITDSEALAR 1818
+ ++ L L P EY VS++A+KG +ES +G FTT G S +T++ +
Sbjct: 1047 SVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVIT 1106
Query: 1819 WQPAIATVDSYVISYTGEKVPEITRTVSGNTVEYALTDLEPATEYTLRI-FAEKGPQKSS 1877
W PA + + + E R V+ ++ ++ L P EY I G ++ +
Sbjct: 1107 WTPAPRI--GFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDA 1164
Query: 1878 TITAKFTTDLDSPRDLTATEVQSETALLT--W-RPPRASVTGYLLVYESVD---GTVKEV 1931
I K T L P +L E +T +LT W R +TGY + + G E
Sbjct: 1165 PIVNKVVTPLSPPTNL-HLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEE 1223
Query: 1932 IVGPDTTSYSLADLSPSTHYTAKIQALNGPLRSNMIQTIFTTIGLLYPFPKDCSQAMLNG 1991
+V D +S + +LSP Y + + S I TI P P D +
Sbjct: 1224 VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKES---VPISDTIIPAVPPPTDLRFTNIGP 1280
Query: 1992 DT 1993
DT
Sbjct: 1281 DT 1282
>gi|14192943 multiple EGF-like-domains 10 [Homo sapiens]
Length = 1140
Score = 237 bits (604), Expect = 1e-61
Identities = 189/638 (29%), Positives = 243/638 (38%), Gaps = 200/638 (31%)
Query: 174 CVCEPGWKGPNCSE--------PECPGNCHLRGRC----IDGQCICDDGFTG----EDCS 217
C CEPGW G NCS P C C + I G C C GF G + C
Sbjct: 124 CQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALCNPITGACHCAAGFRGWRCEDRCE 183
Query: 218 QLACPSDCNDQGKCVNGV--------CICFEGYAGADCSREICP-----------VPCSE 258
Q +DC+ + +C NG C C GY GA C ++CP PC +
Sbjct: 184 QGTYGNDCHQRCQCQNGATCDHVTGECRCPPGYTGAFCE-DLCPPGKHGPQCEQRCPC-Q 241
Query: 259 EHGTC--VDGLCVCHDGFAGDDCNKPL--------CLNNC--YNRGRC--VENECVCDEG 304
G C V G C C G+ G C +P C C +N G C +C C G
Sbjct: 242 NGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSPG 301
Query: 305 FTGEDCSE--------LICPN--DCFDRGRC--INGTCYCEEGFTGEDCGKPTCP----- 347
+TGE C + ++C C + G+C ++G C CE GF GE C CP
Sbjct: 302 YTGERCQDECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLYG 361
Query: 348 --------------HACHTQGRCEEGQCVCDEGFAGVDCSEKRCP----------ADCHN 383
H+CH G+C C G++G+ C+E P C N
Sbjct: 362 IKCDKRCPCHLENTHSCHPM----SGECACKPGWSGLYCNETCSPGFYGEACQQICSCQN 417
Query: 384 RGRC--VDGRCECDDGFTGADCGELKCPNG-----CSGHGRC--------VNGQCVCDEG 428
C V G+C C GF G DC CP G CS C V+G C C G
Sbjct: 418 GADCDSVTGKCTCAPGFKGIDC-STPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAG 476
Query: 429 YTGEDCSQLRCPN-----------DCHSRGRC--VEGKCVCEQGFKGYDCS--------- 466
+ G DCS +RCP+ C + G C ++G C C G++G C
Sbjct: 477 WHGVDCS-IRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYG 535
Query: 467 -------DMSCPNDCHQ---HGRCVNGM------CVCDDGYTGEDCRDRQCPRDCSNRGL 510
D S + CH H RC+ G VC +G G +C P C N
Sbjct: 536 LNCAERCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNC---SLPCYCKNGAS 592
Query: 511 CV--DGQCVCEDGFTGPDCAEL------------SCPNDCHGQGRC--VNGQCVCHEGFM 554
C DG C C GF G C + +CP H G C + G C C GF
Sbjct: 593 CSPDDGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFT 652
Query: 555 GKDCKEQRCPS-----------DCHGQGRC--VDGQCICHEGFTGLDCGQ---------- 591
G C E CPS C G C +D C C+ G+ G DC Q
Sbjct: 653 GALCNEV-CPSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPN 711
Query: 592 --HSCPSDCNNLGQC--VSGRCICNEGYSGEDCSEVSP 625
H+C +C+N C G C C G++G C++ P
Sbjct: 712 CIHTC--NCHNGAFCSAYDGECKCTPGWTGLYCTQRCP 747
Score = 233 bits (594), Expect = 2e-60
Identities = 202/660 (30%), Positives = 254/660 (38%), Gaps = 197/660 (29%)
Query: 137 REQCTAGAGCCLQPATGRLDTRPFCSGRGNFSTEGCGCVCEPGWKGPNCSEPECPGNCHL 196
R QC GA C TG P +G C +C PG GP C E CP C
Sbjct: 194 RCQCQNGATC--DHVTGECRCPPGYTGAF------CEDLCPPGKHGPQC-EQRCP--CQN 242
Query: 197 RGRC--IDGQCICDDGFTGEDCSQLACPS-----------DCNDQGKC--VNGVCICFEG 241
G C + G+C C G+ G C Q CP C++ G C G C C G
Sbjct: 243 GGVCHHVTGECSCPSGWMGTVCGQ-PCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSPG 301
Query: 242 YAGADCSREICPVP-----CSE-----EHGTC--VDGLCVCHDGFAGDDCNKPLCLNNCY 289
Y G C E CPV C+E G C V G C+C GFAG+ C LC Y
Sbjct: 302 YTGERCQDE-CPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLY 360
Query: 290 -------------NRGRC--VENECVCDEGFTGEDCSELICPN----------DCFDRGR 324
N C + EC C G++G C+E P C +
Sbjct: 361 GIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGAD 420
Query: 325 C--INGTCYCEEGFTGEDCGKPTCP---HACHTQGRCE----------EGQCVCDEGFAG 369
C + G C C GF G DC P CP + + RC +G C C G+ G
Sbjct: 421 CDSVTGKCTCAPGFKGIDCSTP-CPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHG 479
Query: 370 VDCSEKRCPA-----------DCHNRGRC--VDGRCECDDGFTGADCGELKCPNG----- 411
VDCS RCP+ C N G C +DG C C G+ G C EL C +G
Sbjct: 480 VDCSI-RCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKC-ELPCQDGTYGLN 537
Query: 412 ------CS---------GHGRCVNG------QCVCDEGYTGEDCSQLRCPNDCHSRGRCV 450
CS GH RC+ G VC EG G +CS P C + C
Sbjct: 538 CAERCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCS---LPCYCKNGASCS 594
Query: 451 --EGKCVCEQGFKGYDCS------------DMSCPNDCHQHGRC--VNGMCVCDDGYTGE 494
+G C C GF+G C +CP H G C + G+C C G+TG
Sbjct: 595 PDDGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGA 654
Query: 495 DCRDRQCPRD-----------CSNRGLC--VDGQCVCEDGFTGPDCAELSCPN------- 534
C + CP C+N G C +D C C G+ G DC++ CP
Sbjct: 655 LCNE-VCPSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQ-PCPPAHWGPNC 712
Query: 535 ----DCHGQGRC--VNGQCVCHEGFMGKDCKEQRCPSDCHGQG-----RC--------VD 575
+CH C +G+C C G+ G C QRCP +G+ +C +
Sbjct: 713 IHTCNCHNGAFCSAYDGECKCTPGWTGLYCT-QRCPLGFYGKDCALICQCQNGADCDHIS 771
Query: 576 GQCICHEGFTGLDCGQHSCPS-----------DCNNLGQC--VSGRCICNEGYSGEDCSE 622
GQC C GF G C Q CPS DC N C ++G C C+ G+ G C +
Sbjct: 772 GQCTCRTGFMGRHCEQ-KCPSGTYGYGCRQICDCLNNSTCDHITGTCYCSPGWKGARCDQ 830
Score = 200 bits (508), Expect = 1e-50
Identities = 170/566 (30%), Positives = 218/566 (38%), Gaps = 170/566 (30%)
Query: 221 CPSDCNDQGKCVNGVCI------CFEGYAGADCSREI--------CPVPCSEEHGTC--- 263
C C D KCV+G CI C G+ G +CS C C ++G
Sbjct: 105 CVPHCAD--KCVHGRCIAPNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALCNP 162
Query: 264 VDGLCVCHDGFAG----DDCNKPLCLNNCYNRGRC--------VENECVCDEGFTGEDCS 311
+ G C C GF G D C + N+C+ R +C V EC C G+TG C
Sbjct: 163 ITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTGECRCPPGYTGAFCE 222
Query: 312 ELICPN----------DCFDRGRC--INGTCYCEEGFTGEDCGKPTCPHA---------- 349
+L P C + G C + G C C G+ G CG+P CP
Sbjct: 223 DLCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSGWMGTVCGQP-CPEGRFGKNCSQEC 281
Query: 350 -CHTQGRCE--EGQCVCDEGFAGVDCSEKRCP-----------ADCHNRGRC--VDGRCE 393
CH G C+ GQC C G+ G C ++ CP C N G+C V G C
Sbjct: 282 QCHNGGTCDAATGQCHCSPGYTGERCQDE-CPVGTYGVLCAETCQCVNGGKCYHVSGACL 340
Query: 394 CDDGFTGADCGELKCPNGCSG---HGRC------------VNGQCVCDEGYTGEDCSQLR 438
C+ GF G C CP G G RC ++G+C C G++G C++
Sbjct: 341 CEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNETC 400
Query: 439 CPN----------DCHSRGRC--VEGKCVCEQGFKGYDCSDMSCP-----NDCHQHGRC- 480
P C + C V GKC C GFKG DCS CP +C C
Sbjct: 401 SPGFYGEACQQICSCQNGADCDSVTGKCTCAPGFKGIDCS-TPCPLGTYGINCSSRCGCK 459
Query: 481 -------VNGMCVCDDGYTGEDCRDRQCPR-----------DCSNRGLC--VDGQCV--- 517
V+G C C G+ G DC R CP C N G C +DG C
Sbjct: 460 NDAVCSPVDGSCTCKAGWHGVDCSIR-CPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAP 518
Query: 518 ----------CEDGFTGPDCAE---LSCPNDCH---GQGRCVNG------QCVCHEGFMG 555
C+DG G +CAE S + CH G RC+ G VC EG G
Sbjct: 519 GWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWG 578
Query: 556 KDCKEQRCPSDCHGQGRCV--DGQCICHEGFTGLDCGQ------------HSCPSDCNNL 601
+C P C C DG C C GF G C + +CP ++
Sbjct: 579 PNCS---LPCYCKNGASCSPDDGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSS 635
Query: 602 GQC--VSGRCICNEGYSGEDCSEVSP 625
G C ++G C C G++G C+EV P
Sbjct: 636 GPCHHITGLCDCLPGFTGALCNEVCP 661
Score = 184 bits (466), Expect = 1e-45
Identities = 146/459 (31%), Positives = 185/459 (40%), Gaps = 135/459 (29%)
Query: 270 CHDGF--AGDDCNKPLCLNNCYNRGRCVE-NECVCDEGFTGEDCSELICPND-----CFD 321
C GF +G+ C P C + C + GRC+ N C C+ G+ G +CS C D C
Sbjct: 94 CCPGFYESGEMC-VPHCADKCVH-GRCIAPNTCQCEPGWGGTNCSS-ACDGDHWGPHCTS 150
Query: 322 RGRC--------INGTCYCEEGFTG----EDCGKPTCPHACHTQGRCEE--------GQC 361
R +C I G C+C GF G + C + T + CH + +C+ G+C
Sbjct: 151 RCQCKNGALCNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTGEC 210
Query: 362 VCDEGFAGVDCS------------EKRCPADCHNRGRC--VDGRCECDDGFTGADCGELK 407
C G+ G C E+RCP C N G C V G C C G+ G CG+
Sbjct: 211 RCPPGYTGAFCEDLCPPGKHGPQCEQRCP--CQNGGVCHHVTGECSCPSGWMGTVCGQ-P 267
Query: 408 CPNG-----CSGHGRCVN--------GQCVCDEGYTGEDCSQLRCP-----------NDC 443
CP G CS +C N GQC C GYTGE C Q CP C
Sbjct: 268 CPEGRFGKNCSQECQCHNGGTCDAATGQCHCSPGYTGERC-QDECPVGTYGVLCAETCQC 326
Query: 444 HSRGRC--VEGKCVCEQGFKGYDCSDMSCPNDCHQHGRCVNGMCVCDDGYTGEDCRDRQC 501
+ G+C V G C+CE GF G C CP +G G C D++C
Sbjct: 327 VNGGKCYHVSGACLCEAGFAGERCEARLCP-----------------EGLYGIKC-DKRC 368
Query: 502 PRDCSNRGLC--VDGQCVCEDGFTGPDCAELSCPN----------DCHGQGRC--VNGQC 547
P N C + G+C C+ G++G C E P C C V G+C
Sbjct: 369 PCHLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTGKC 428
Query: 548 VCHEGFMGKDCKEQRCPSDCHG---QGRC----------VDGQCICHEGFTGLDCGQHSC 594
C GF G DC CP +G RC VDG C C G+ G+DC C
Sbjct: 429 TCAPGFKGIDCSTP-CPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIR-C 486
Query: 595 PS-----------DCNNLGQC--VSGRCICNEGYSGEDC 620
PS C N G C + G C C G+ GE C
Sbjct: 487 PSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKC 525
Score = 151 bits (381), Expect = 8e-36
Identities = 127/390 (32%), Positives = 161/390 (41%), Gaps = 104/390 (26%)
Query: 301 CDEGF--TGEDCSELICPNDCFDRGRCIN-GTCYCEEGFTGEDC-----GKPTCPHACHT 352
C GF +GE C C + C GRCI TC CE G+ G +C G PH C +
Sbjct: 94 CCPGFYESGEMCVPH-CADKCV-HGRCIAPNTCQCEPGWGGTNCSSACDGDHWGPH-CTS 150
Query: 353 QGRCEEGQ--------CVCDEGFAGVDCSEKRCPA-----DCHNRGRCVDGRCECDDGFT 399
+ +C+ G C C GF G C E RC DCH R +C +G CD
Sbjct: 151 RCQCKNGALCNPITGACHCAAGFRGWRC-EDRCEQGTYGNDCHQRCQCQNG-ATCDHV-- 206
Query: 400 GADCGELKCPNGCSGHGRCVNGQCVCDEGYTGEDCSQLRCPNDCHSRGRC--VEGKCVCE 457
GE +CP G +G C + +C G G C Q RCP C + G C V G+C C
Sbjct: 207 ---TGECRCPPGYTG-AFCED---LCPPGKHGPQCEQ-RCP--CQNGGVCHHVTGECSCP 256
Query: 458 QGFKGYDCSDMSCPN-----------DCHQHGRC--VNGMCVCDDGYTGEDCRDRQCPRD 504
G+ G C CP CH G C G C C GYTGE C+D
Sbjct: 257 SGWMGTVCGQ-PCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSPGYTGERCQDE----- 310
Query: 505 CSNRGLCVDGQCVCEDGFTGPDCAELSCPNDCHGQGRC--VNGQCVCHEGFMGKDCKEQR 562
C G G CAE +C C G+C V+G C+C GF G+ C+ +
Sbjct: 311 -------------CPVGTYGVLCAE-TC--QCVNGGKCYHVSGACLCEAGFAGERCEARL 354
Query: 563 CPSDCHG---QGRC------------VDGQCICHEGFTGLDCGQHSCPS----------D 597
CP +G RC + G+C C G++GL C + P
Sbjct: 355 CPEGLYGIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICS 414
Query: 598 CNNLGQC--VSGRCICNEGYSGEDCSEVSP 625
C N C V+G+C C G+ G DCS P
Sbjct: 415 CQNGADCDSVTGKCTCAPGFKGIDCSTPCP 444
Score = 136 bits (343), Expect = 2e-31
Identities = 100/320 (31%), Positives = 133/320 (41%), Gaps = 92/320 (28%)
Query: 391 RCECDDGFTGADCGELKCPNGCSG---HGRCVN-GQCVCDEGYTGEDCSQLRCPND---- 442
+ +C GF + GE+ P+ C+ HGRC+ C C+ G+ G +CS C D
Sbjct: 91 KSQCCPGFY--ESGEMCVPH-CADKCVHGRCIAPNTCQCEPGWGGTNCSSA-CDGDHWGP 146
Query: 443 -CHSRGRC--------VEGKCVCEQGFKGYDCSDM----SCPNDCHQHGRCVNGM----- 484
C SR +C + G C C GF+G+ C D + NDCHQ +C NG
Sbjct: 147 HCTSRCQCKNGALCNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHV 206
Query: 485 ---CVCDDGYTGEDCRD------------RQCPRDCSNRGLC--VDGQCVCEDGFTGPDC 527
C C GYTG C D ++CP C N G+C V G+C C G+ G C
Sbjct: 207 TGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCP--CQNGGVCHHVTGECSCPSGWMGTVC 264
Query: 528 AELSCPN-----------DCHGQGRC--VNGQCVCHEGFMGKDCKEQRCP---------- 564
+ CP CH G C GQC C G+ G+ C+++ CP
Sbjct: 265 GQ-PCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSPGYTGERCQDE-CPVGTYGVLCAE 322
Query: 565 -SDCHGQGRC--VDGQCICHEGFTGLDCGQHSCPSD-----CNNLGQC----------VS 606
C G+C V G C+C GF G C CP C+ C +S
Sbjct: 323 TCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSCHPMS 382
Query: 607 GRCICNEGYSGEDCSEVSPP 626
G C C G+SG C+E P
Sbjct: 383 GECACKPGWSGLYCNETCSP 402
>gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]
Length = 1044
Score = 234 bits (598), Expect = 5e-61
Identities = 175/586 (29%), Positives = 230/586 (39%), Gaps = 180/586 (30%)
Query: 174 CVCEPGWKGPNCSEPECPGN----------CHLRGRC--IDGQCICDDGFTGEDCSQLAC 221
C C PGW G C++P PG CH G+C + GQC C G+ G+ C + C
Sbjct: 247 CACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQE-EC 305
Query: 222 P-----------SDCNDQGKC--VNGVCICFEGYAGADCSREICP-----------VPCS 257
P DC++ G+C G C C GY G C +CP PC
Sbjct: 306 PFGSFGFQCSQHCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCD 365
Query: 258 EEHG-TC--VDGLCVCHDGFAGDDCNKPLCLNNCYNRGRCVENECVCDEGFTGEDCSELI 314
++ +C V G C C G++G CN+ C G+ G+ C
Sbjct: 366 ADNTISCHPVTGACTCQPGWSGHHCNES------------------CPVGYYGDGCQ--- 404
Query: 315 CPNDCFDRGRC--INGTCYCEEGFTGEDCGK--------PTCPH--ACHTQGRCE--EGQ 360
P C + C I G C C GF GE C P C +C+ G C +G
Sbjct: 405 LPCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGS 464
Query: 361 CVCDEGFAGVDCSEKRCPAD-----------CHNRGRC--VDGRCECDDGFTGADCGELK 407
C C EG+ G+DC+ CP+ C N C +DG C C G+ G C EL
Sbjct: 465 CTCKEGWQGLDCTLP-CPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTC-ELP 522
Query: 408 CPNG-----CSGHGRC--------VNGQCVCDEGYTGEDCSQLRCPN----------DCH 444
CP+G CS H C V G C C G+TG C P C
Sbjct: 523 CPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCE 582
Query: 445 SRGRCV--EGKCVCEQGFKGYDCSDMS------------CPNDCHQHGRC--VNGMCVCD 488
+ G C +G C C GF+G C + CP H C ++G+C C
Sbjct: 583 NGGSCSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECL 642
Query: 489 DGYTGEDCRDRQCPRDCSNRGLCVDGQCVCEDGFTGPDCAELSCPNDCHGQGRC--VNGQ 546
G++G C VC G+ G DCA+L C G C ++G
Sbjct: 643 PGFSGALCNQ------------------VCAGGYFGQDCAQLC---SCANNGTCSPIDGS 681
Query: 547 CVCHEGFMGKDCKEQRCPS-----------DCHGQGRCV--DGQCICHEGFTGLDCGQHS 593
C C G++GKDC Q CP CH C DG C C G+TGL C Q
Sbjct: 682 CQCFPGWIGKDCS-QACPPGFWGPACFHACSCHNGASCSAEDGACHCTPGWTGLFCTQR- 739
Query: 594 CPS-----DCNNLGQC--------VSGRCICNEGYSGEDCSEVSPP 626
CP+ DC + QC +SG+C C G++G+ C + P
Sbjct: 740 CPAAFFGKDCGRVCQCQNGASCDHISGKCTCRTGFTGQHCEQRCAP 785
Score = 233 bits (593), Expect = 2e-60
Identities = 185/632 (29%), Positives = 242/632 (38%), Gaps = 188/632 (29%)
Query: 174 CVCEPGWKGPNCSE--------PECPGNCHLRGRC----IDGQCICDDGFTGEDCSQLAC 221
C CEPGW GP+CS P C C + I G C+C GF G C +L
Sbjct: 118 CHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALCNPITGACVCAAGFRGWRCEELCA 177
Query: 222 PS----------DCNDQGKC--VNGVCICFEGYAGADCSREICP-----------VPCSE 258
P C C G C+C GY G C E+CP PC +
Sbjct: 178 PGTHGKGCQLPCQCRHGASCDPRAGECLCAPGYTGVYC-EELCPPGSHGAHCELRCPC-Q 235
Query: 259 EHGTC--VDGLCVCHDGFAGDDCNKPL--------CLNN--CYNRGRC--VENECVCDEG 304
GTC + G C C G+ G C +P C + C++ G+C V +C C G
Sbjct: 236 NGGTCHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAG 295
Query: 305 FTGEDCSELICP-----------NDCFDRGRC--INGTCYCEEGFTGEDCGKPTCPHACH 351
+ G+ C E CP DC + G+C G C CE G+ G C + CP H
Sbjct: 296 YMGDRCQE-ECPFGSFGFQCSQHCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLH 354
Query: 352 TQG-----RCE----------EGQCVCDEGFAGVDCSEK----------RCPADCHNRGR 386
G C+ G C C G++G C+E + P C N
Sbjct: 355 GPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGAD 414
Query: 387 C--VDGRCECDDGFTGADCGELKCPNG-----------CSGHGRC--VNGQCVCDEGYTG 431
C + G C C GF G C + C G C+ G C V+G C C EG+ G
Sbjct: 415 CHSITGGCTCAPGFMGEVCA-VSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQG 473
Query: 432 EDCSQLRCPN-----DCHSRGRC--------VEGKCVCEQGFKGYDCSDMSCPN-----D 473
DC+ L CP+ +C+ C ++G C C G+ G C ++ CP+ +
Sbjct: 474 LDCT-LPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTC-ELPCPDGTFGLN 531
Query: 474 CHQHGRC--------VNGMCVCDDGYTGEDCRDRQCPR-----------DCSNRGLC--V 512
C +H C V G C C G+TG C D CP C N G C
Sbjct: 532 CSEHCDCSHADGCDPVTGHCCCLAGWTGIRC-DSTCPPGRWGPNCSVSCSCENGGSCSPE 590
Query: 513 DGQCVCEDGFTGPDCAEL------------SCPNDCHGQGRC--VNGQCVCHEGFMGKDC 558
DG C C GF GP C + CP H C ++G C C GF G C
Sbjct: 591 DGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALC 650
Query: 559 KE--------QRCPS--DCHGQGRC--VDGQCICHEGFTGLDCGQHSCP----------- 595
+ Q C C G C +DG C C G+ G DC Q +CP
Sbjct: 651 NQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQ-ACPPGFWGPACFHA 709
Query: 596 SDCNNLGQCVS--GRCICNEGYSGEDCSEVSP 625
C+N C + G C C G++G C++ P
Sbjct: 710 CSCHNGASCSAEDGACHCTPGWTGLFCTQRCP 741
Score = 206 bits (523), Expect = 3e-52
Identities = 167/552 (30%), Positives = 219/552 (39%), Gaps = 168/552 (30%)
Query: 161 CSGRGNFSTEGCGCVCEPGWKGPNCSEPECPGNCHLRGRCIDGQCICDDGFTGEDCSQLA 220
C G S C CEPG+KGP C E CP +G G C+ L
Sbjct: 320 CHNGGQCSPTTGACECEPGYKGPRCQERLCP-----------------EGLHGPGCT-LP 361
Query: 221 CPSDCNDQGKC--VNGVCICFEGYAGADCSREICPV---------PCSEEHGT---CVDG 266
CP D ++ C V G C C G++G C+ E CPV PC+ ++G + G
Sbjct: 362 CPCDADNTISCHPVTGACTCQPGWSGHHCN-ESCPVGYYGDGCQLPCTCQNGADCHSITG 420
Query: 267 LCVCHDGFAGDDC--------NKPLC--LNNCYNRGRC--VENECVCDEGFTGEDCSELI 314
C C GF G+ C P C + +C N G C V+ C C EG+ G DC+ L
Sbjct: 421 GCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCT-LP 479
Query: 315 CPN-----DCFDRGRC--------INGTCYCEEGFTGEDCGKP--------TCPHAC--- 350
CP+ +C + C I+G+C C G+ G+ C P C C
Sbjct: 480 CPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCS 539
Query: 351 HTQGRCE--EGQCVCDEGFAGVDCSEKRCP-----------ADCHNRGRC--VDGRCECD 395
H G C+ G C C G+ G+ C + CP C N G C DG CEC
Sbjct: 540 HADG-CDPVTGHCCCLAGWTGIRC-DSTCPPGRWGPNCSVSCSCENGGSCSPEDGSCECA 597
Query: 396 DGFTGADCGELKCPNGCSGHG---------------RCVNGQCVCDEGYTGEDCSQLRCP 440
GF G C + CP G GHG ++G C C G++G C+Q
Sbjct: 598 PGFRGPLCQRI-CPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQ---- 652
Query: 441 NDCHSRGRCVEGKCVCEQGFKGYDCSDMSCPNDCHQHGRC--VNGMCVCDDGYTGEDCRD 498
VC G+ G DC+ + C +G C ++G C C G+ G+DC
Sbjct: 653 --------------VCAGGYFGQDCAQLC---SCANNGTCSPIDGSCQCFPGWIGKDC-S 694
Query: 499 RQCPR-----------DCSNRGLC--VDGQCVCEDGFTGPDCAELSCP-----NDCHGQG 540
+ CP C N C DG C C G+TG C + CP DC
Sbjct: 695 QACPPGFWGPACFHACSCHNGASCSAEDGACHCTPGWTGLFCTQ-RCPAAFFGKDCGRVC 753
Query: 541 RC--------VNGQCVCHEGFMGKDCKEQRCPSDCHGQG-----RC--------VDGQCI 579
+C ++G+C C GF G+ C EQRC G G C V G C
Sbjct: 754 QCQNGASCDHISGKCTCRTGFTGQHC-EQRCAPGTFGYGCQQLCECMNNSTCDHVTGTCY 812
Query: 580 CHEGFTGLDCGQ 591
C GF G+ C Q
Sbjct: 813 CSPGFKGIRCDQ 824
Score = 176 bits (447), Expect = 2e-43
Identities = 136/419 (32%), Positives = 164/419 (39%), Gaps = 119/419 (28%)
Query: 301 CDEGF--TGEDCSELICPNDCFDRGRCIN-GTCYCEEGFTGEDCGK--------PTCPHA 349
C G+ +G+ C L C +C GRC++ TC+CE G+ G DC P C +
Sbjct: 88 CCPGYYESGDFCIPL-CTEECV-HGRCVSPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNR 145
Query: 350 CHTQGR--CEE--GQCVCDEGFAGVDCSE--------KRC--PADCHNRGRCVD--GRCE 393
C Q C G CVC GF G C E K C P C + C G C
Sbjct: 146 CQCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDPRAGECL 205
Query: 394 CDDGFTGADCGELKCPNG-----------CSGHGRC--VNGQCVCDEGYTGEDCSQLRCP 440
C G+TG C EL CP G C G C + G+C C G+TG C+Q
Sbjct: 206 CAPGYTGVYCEEL-CPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCAQ---- 260
Query: 441 NDCHSRGRCVEGKCVCEQGFKGYDCSDMSCPNDCHQHGRC--VNGMCVCDDGYTGEDCRD 498
C G G +CS CP CH G+C V G C C GY G+ C++
Sbjct: 261 --------------PCPPGTFGQNCSQ-DCP--CHHGGQCDHVTGQCHCTAGYMGDRCQE 303
Query: 499 R--------QCPR--DCSNRGLC--VDGQCVCEDGFTGPDCAELSCPNDCHGQG------ 540
QC + DC N G C G C CE G+ GP C E CP HG G
Sbjct: 304 ECPFGSFGFQCSQHCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCP 363
Query: 541 ---------RCVNGQCVCHEGFMGKDCKEQRCPSDCHGQG-------------RCVDGQC 578
V G C C G+ G C E CP +G G + G C
Sbjct: 364 CDADNTISCHPVTGACTCQPGWSGHHCNES-CPVGYYGDGCQLPCTCQNGADCHSITGGC 422
Query: 579 ICHEGFTGLDCGQH--------SCPS--DCNNLGQC--VSGRCICNEGYSGEDCSEVSP 625
C GF G C +C S CNN G C V G C C EG+ G DC+ P
Sbjct: 423 TCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCP 481
Score = 129 bits (324), Expect = 3e-29
Identities = 97/295 (32%), Positives = 128/295 (43%), Gaps = 82/295 (27%)
Query: 391 RCECDDGF--TGADCGELKCPNGCSGHGRCVNGQ-CVCDEGYTGEDCSQLRCPND----- 442
R +C G+ +G C L C C HGRCV+ C C+ G+ G DCS C +D
Sbjct: 85 RSQCCPGYYESGDFCIPL-CTEECV-HGRCVSPDTCHCEPGWGGPDCSS-GCDSDHWGPH 141
Query: 443 CHSRGRC--------VEGKCVCEQGFKGYDCSDMSCPND--------CH-QHGRCVN--- 482
C +R +C + G CVC GF+G+ C ++ P C +HG +
Sbjct: 142 CSNRCQCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDPRA 201
Query: 483 GMCVCDDGYTGEDCRDR------------QCPRDCSNRGLC--VDGQCVCEDGFTGPDCA 528
G C+C GYTG C + +CP C N G C + G+C C G+TG CA
Sbjct: 202 GECLCAPGYTGVYCEELCPPGSHGAHCELRCP--CQNGGTCHHITGECACPPGWTGAVCA 259
Query: 529 E--------LSCPNDC--HGQGRC--VNGQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDG 576
+ +C DC H G+C V GQC C G+MG C+E+
Sbjct: 260 QPCPPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEE--------------- 304
Query: 577 QCICHEGFTGLDCGQHSCPSDCNNLGQC--VSGRCICNEGYSGEDCSEVSPPKDL 629
C G G C QH DC+N GQC +G C C GY G C E P+ L
Sbjct: 305 ---CPFGSFGFQCSQHC---DCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGL 353
>gi|170016091 odz, odd Oz/ten-m homolog 2 [Homo sapiens]
Length = 2765
Score = 233 bits (595), Expect = 1e-60
Identities = 116/308 (37%), Positives = 163/308 (52%), Gaps = 30/308 (9%)
Query: 221 CPSDCNDQGKCVNGVCICFEGYAGADCSREICPVPCSEEHGTCVDGLCVCHDGFAGDDCN 280
CP +C+ G+CV+GVC CF G+ GADC++ CPV CS +G G C C+ G+ G +C+
Sbjct: 576 CPRNCHGNGECVSGVCHCFPGFLGADCAKAACPVLCSG-NGQYSKGTCQCYSGWKGAECD 634
Query: 281 KPL--CLN-NCYNRGRCVENECVCDEGFTGEDCSELICPND-CFDRGRCINGTCYCEEGF 336
P+ C++ +C G C++ CVC G+ GE C E+ C + C G C+NG C C G+
Sbjct: 635 VPMNQCIDPSCGGHGSCIDGNCVCSAGYKGEHCEEVDCLDPTCSSHGVCVNGECLCSPGW 694
Query: 337 TGEDC--GKPTCPHACHTQGRC--EEGQCVCDEGFAGVDCSEKRCPADCHNRGRCVDGRC 392
G +C + CP C G + G C CD + G DCS + C DC G C+ G C
Sbjct: 695 GGLNCELARVQCPDQCSGHGTYLPDTGLCSCDPNWMGPDCSVEVCSVDCGTHGVCIGGAC 754
Query: 393 ECDDGFTGADCGELKCPNGCSGHGRCVNGQCVCDEGYTGEDCSQLRCPNDCHSRGRCVEG 452
C++G+TGA C + C C HG C +G+C C EG+ GE C+ CP+ C+ GRC G
Sbjct: 755 RCEEGWTGAACDQRVCHPRCIEHGTCKDGKCECREGWNGEHCTIDGCPDLCNGNGRCTLG 814
Query: 453 ----KCVCEQGFKGYDCS---DMSCPNDCHQHGRCVNGMCVCDDGYTGEDCRDRQC--PR 503
+CVC+ G++G C+ + SC ++ G DG DC D C
Sbjct: 815 QNSWQCVCQTGWRGPGCNVAMETSCADNKDNEG----------DGLV--DCLDPDCCLQS 862
Query: 504 DCSNRGLC 511
C N LC
Sbjct: 863 ACQNSLLC 870
Score = 231 bits (589), Expect = 6e-60
Identities = 107/283 (37%), Positives = 145/283 (51%), Gaps = 19/283 (6%)
Query: 315 CPNDCFDRGRCINGTCYCEEGFTGEDCGKPTCPHACHTQGRCEEGQCVCDEGFAGVDCSE 374
CP +C G C++G C+C GF G DC K CP C G+ +G C C G+ G +C
Sbjct: 576 CPRNCHGNGECVSGVCHCFPGFLGADCAKAACPVLCSGNGQYSKGTCQCYSGWKGAECDV 635
Query: 375 --KRC-PADCHNRGRCVDGRCECDDGFTGADCGELKCPNG-CSGHGRCVNGQCVCDEGYT 430
+C C G C+DG C C G+ G C E+ C + CS HG CVNG+C+C G+
Sbjct: 636 PMNQCIDPSCGGHGSCIDGNCVCSAGYKGEHCEEVDCLDPTCSSHGVCVNGECLCSPGWG 695
Query: 431 GEDC--SQLRCPNDCHSRGRCVE--GKCVCEQGFKGYDCSDMSCPNDCHQHGRCVNGMCV 486
G +C ++++CP+ C G + G C C+ + G DCS C DC HG C+ G C
Sbjct: 696 GLNCELARVQCPDQCSGHGTYLPDTGLCSCDPNWMGPDCSVEVCSVDCGTHGVCIGGACR 755
Query: 487 CDDGYTGEDCRDRQCPRDCSNRGLCVDGQCVCEDGFTGPDCAELSCPNDCHGQGRCVNG- 545
C++G+TG C R C C G C DG+C C +G+ G C CP+ C+G GRC G
Sbjct: 756 CEEGWTGAACDQRVCHPRCIEHGTCKDGKCECREGWNGEHCTIDGCPDLCNGNGRCTLGQ 815
Query: 546 ---QCVCHEGFMGKDCK---EQRCPSDCHGQG----RCVDGQC 578
QCVC G+ G C E C + +G C+D C
Sbjct: 816 NSWQCVCQTGWRGPGCNVAMETSCADNKDNEGDGLVDCLDPDC 858
Score = 226 bits (575), Expect = 2e-58
Identities = 116/335 (34%), Positives = 160/335 (47%), Gaps = 34/335 (10%)
Query: 186 SEPECPGNCHLRGRCIDGQCICDDGFTGEDCSQLACPSDCNDQGKCVNGVCICFEGYAGA 245
S +CP NCH G C+ G C C GF G DC++ ACP C+ G+ G C C+ G+ GA
Sbjct: 572 SVQDCPRNCHGNGECVSGVCHCFPGFLGADCAKAACPVLCSGNGQYSKGTCQCYSGWKGA 631
Query: 246 DCSREI--CPVPCSEEHGTCVDGLCVCHDGFAGDDCNKPLCLN-NCYNRGRCVENECVCD 302
+C + C P HG+C+DG CVC G+ G+ C + CL+ C + G CV EC+C
Sbjct: 632 ECDVPMNQCIDPSCGGHGSCIDGNCVCSAGYKGEHCEEVDCLDPTCSSHGVCVNGECLCS 691
Query: 303 EGFTGEDC--SELICPNDCFDRGRCI--NGTCYCEEGFTGEDCGKPTCPHACHTQGRCEE 358
G+ G +C + + CP+ C G + G C C+ + G DC C C T G C
Sbjct: 692 PGWGGLNCELARVQCPDQCSGHGTYLPDTGLCSCDPNWMGPDCSVEVCSVDCGTHGVCIG 751
Query: 359 GQCVCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECDDGFTGADCGELKCPNGCSGHGRC 418
G C C+EG+ G C ++ C C G C DG+CEC +G+ G C CP+ C+G+GRC
Sbjct: 752 GACRCEEGWTGAACDQRVCHPRCIEHGTCKDGKCECREGWNGEHCTIDGCPDLCNGNGRC 811
Query: 419 VNG----QCVCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCEQGFKGYDCSDMSCPNDC 474
G QCVC G+ G C+ +E C + +G D P DC
Sbjct: 812 TLGQNSWQCVCQTGWRGPGCNV------------AMETSCADNKDNEGDGLVDCLDP-DC 858
Query: 475 HQHGRCVNGMCVCDDGYTGEDCRDRQCPRDCSNRG 509
C N + CR + P D +G
Sbjct: 859 CLQSACQNSLL----------CRGSRDPLDIIQQG 883
Score = 223 bits (569), Expect = 1e-57
Identities = 103/261 (39%), Positives = 136/261 (52%), Gaps = 12/261 (4%)
Query: 373 SEKRCPADCHNRGRCVDGRCECDDGFTGADCGELKCPNGCSGHGRCVNGQCVCDEGYTGE 432
S + CP +CH G CV G C C GF GADC + CP CSG+G+ G C C G+ G
Sbjct: 572 SVQDCPRNCHGNGECVSGVCHCFPGFLGADCAKAACPVLCSGNGQYSKGTCQCYSGWKGA 631
Query: 433 DCS--QLRCPN-DCHSRGRCVEGKCVCEQGFKGYDCSDMSCPND-CHQHGRCVNGMCVCD 488
+C +C + C G C++G CVC G+KG C ++ C + C HG CVNG C+C
Sbjct: 632 ECDVPMNQCIDPSCGGHGSCIDGNCVCSAGYKGEHCEEVDCLDPTCSSHGVCVNGECLCS 691
Query: 489 DGYTGEDCRDR--QCPRDCSNRGLCVD--GQCVCEDGFTGPDCAELSCPNDCHGQGRCVN 544
G+ G +C QCP CS G + G C C+ + GPDC+ C DC G C+
Sbjct: 692 PGWGGLNCELARVQCPDQCSGHGTYLPDTGLCSCDPNWMGPDCSVEVCSVDCGTHGVCIG 751
Query: 545 GQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLDCGQHSCPSDCNNLGQC 604
G C C EG+ G C ++ C C G C DG+C C EG+ G C CP CN G+C
Sbjct: 752 GACRCEEGWTGAACDQRVCHPRCIEHGTCKDGKCECREGWNGEHCTIDGCPDLCNGNGRC 811
Query: 605 VSG----RCICNEGYSGEDCS 621
G +C+C G+ G C+
Sbjct: 812 TLGQNSWQCVCQTGWRGPGCN 832
Score = 189 bits (479), Expect = 3e-47
Identities = 103/306 (33%), Positives = 138/306 (45%), Gaps = 32/306 (10%)
Query: 161 CSGRGNFSTEGCGCVCEPGWKGPNCSEPECPGNCHLRGRCIDGQCICDDGFTGEDC---- 216
C G G + C C PG+ G +C++ CP C G+ G C C G+ G +C
Sbjct: 580 CHGNGECVSGVCHCF--PGFLGADCAKAACPVLCSGNGQYSKGTCQCYSGWKGAECDVPM 637
Query: 217 SQLACPSDCNDQGKCVNGVCICFEGYAGADCSREICPVPCSEEHGTCVDGLCVCHDGFAG 276
+Q PS C G C++G C+C GY G C C P HG CV+G C+C G+ G
Sbjct: 638 NQCIDPS-CGGHGSCIDGNCVCSAGYKGEHCEEVDCLDPTCSSHGVCVNGECLCSPGWGG 696
Query: 277 DDCN--KPLCLNNCYNRGRCVENE--CVCDEGFTGEDCSELICPNDCFDRGRCINGTCYC 332
+C + C + C G + + C CD + G DCS +C DC G CI G C C
Sbjct: 697 LNCELARVQCPDQCSGHGTYLPDTGLCSCDPNWMGPDCSVEVCSVDCGTHGVCIGGACRC 756
Query: 333 EEGFTGEDCGKPTCPHACHTQGRCEEGQCVCDEGFAGVDCSEKRCPADCHNRGRCVDG-- 390
EEG+TG C + C C G C++G+C C EG+ G C+ CP C+ GRC G
Sbjct: 757 EEGWTGAACDQRVCHPRCIEHGTCKDGKCECREGWNGEHCTIDGCPDLCNGNGRCTLGQN 816
Query: 391 --RCECDDGFTGADCG---ELKCPNGCSGHG----RCVNGQCVCDEGYTGEDCSQLRCPN 441
+C C G+ G C E C + G C++ C C Q C N
Sbjct: 817 SWQCVCQTGWRGPGCNVAMETSCADNKDNEGDGLVDCLDPDC----------CLQSACQN 866
Query: 442 DCHSRG 447
RG
Sbjct: 867 SLLCRG 872
Score = 162 bits (411), Expect = 3e-39
Identities = 75/192 (39%), Positives = 97/192 (50%), Gaps = 8/192 (4%)
Query: 439 CPNDCHSRGRCVEGKCVCEQGFKGYDCSDMSCPNDCHQHGRCVNGMCVCDDGYTGEDCRD 498
CP +CH G CV G C C GF G DC+ +CP C +G+ G C C G+ G +C
Sbjct: 576 CPRNCHGNGECVSGVCHCFPGFLGADCAKAACPVLCSGNGQYSKGTCQCYSGWKGAECDV 635
Query: 499 --RQC-PRDCSNRGLCVDGQCVCEDGFTGPDCAELSCPND-CHGQGRCVNGQCVCHEGFM 554
QC C G C+DG CVC G+ G C E+ C + C G CVNG+C+C G+
Sbjct: 636 PMNQCIDPSCGGHGSCIDGNCVCSAGYKGEHCEEVDCLDPTCSSHGVCVNGECLCSPGWG 695
Query: 555 GKDCKEQR--CPSDCHGQGRCVD--GQCICHEGFTGLDCGQHSCPSDCNNLGQCVSGRCI 610
G +C+ R CP C G G + G C C + G DC C DC G C+ G C
Sbjct: 696 GLNCELARVQCPDQCSGHGTYLPDTGLCSCDPNWMGPDCSVEVCSVDCGTHGVCIGGACR 755
Query: 611 CNEGYSGEDCSE 622
C EG++G C +
Sbjct: 756 CEEGWTGAACDQ 767
Score = 130 bits (328), Expect = 1e-29
Identities = 70/193 (36%), Positives = 88/193 (45%), Gaps = 24/193 (12%)
Query: 159 PFCSGRGNFSTEGCGCVCEPGWKGPNC--SEPECPGNCHLRGRCI--DGQCICDDGFTGE 214
P CS G G C+C PGW G NC + +CP C G + G C CD + G
Sbjct: 675 PTCSSHG-VCVNG-ECLCSPGWGGLNCELARVQCPDQCSGHGTYLPDTGLCSCDPNWMGP 732
Query: 215 DCSQLACPSDCNDQGKCVNGVCICFEGYAGADCSREICPVPCSEEHGTCVDGLCVCHDGF 274
DCS C DC G C+ G C C EG+ GA C + +C C EHGTC DG C C +G+
Sbjct: 733 DCSVEVCSVDCGTHGVCIGGACRCEEGWTGAACDQRVCHPRCI-EHGTCKDGKCECREGW 791
Query: 275 AGDDCNKPLCLNNCYNRGRCVEN----ECVCDEGFTGEDCS---ELICPN---------- 317
G+ C C + C GRC +CVC G+ G C+ E C +
Sbjct: 792 NGEHCTIDGCPDLCNGNGRCTLGQNSWQCVCQTGWRGPGCNVAMETSCADNKDNEGDGLV 851
Query: 318 DCFDRGRCINGTC 330
DC D C+ C
Sbjct: 852 DCLDPDCCLQSAC 864
Score = 113 bits (283), Expect = 2e-24
Identities = 65/195 (33%), Positives = 89/195 (45%), Gaps = 23/195 (11%)
Query: 140 CTAGAGCCLQPATGRLDTRPFCSGRGNFSTEGCGCVCEPGWKGPNCSEPECPGNCHLRGR 199
C+ G G L R+ CSG G + + C C+P W GP+CS C +C G
Sbjct: 690 CSPGWGG-LNCELARVQCPDQCSGHGTYLPDTGLCSCDPNWMGPDCSVEVCSVDCGTHGV 748
Query: 200 CIDGQCICDDGFTGEDCSQLACPSDCNDQGKCVNGVCICFEGYAGADCSREICPVPCSEE 259
CI G C C++G+TG C Q C C + G C +G C C EG+ G C+ + CP C+
Sbjct: 749 CIGGACRCEEGWTGAACDQRVCHPRCIEHGTCKDGKCECREGWNGEHCTIDGCPDLCN-G 807
Query: 260 HGTCVDG----LCVCHDGFAGDDCNKPL---CLNNCYNRG----RCVENECVCDEGFTGE 308
+G C G CVC G+ G CN + C +N N G C++ +C
Sbjct: 808 NGRCTLGQNSWQCVCQTGWRGPGCNVAMETSCADNKDNEGDGLVDCLDPDC--------- 858
Query: 309 DCSELICPNDCFDRG 323
C + C N RG
Sbjct: 859 -CLQSACQNSLLCRG 872
Score = 102 bits (253), Expect = 5e-21
Identities = 43/96 (44%), Positives = 55/96 (57%), Gaps = 5/96 (5%)
Query: 532 CPNDCHGQGRCVNGQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLDCG- 590
CP +CHG G CV+G C C GF+G DC + CP C G G+ G C C+ G+ G +C
Sbjct: 576 CPRNCHGNGECVSGVCHCFPGFLGADCAKAACPVLCSGNGQYSKGTCQCYSGWKGAECDV 635
Query: 591 -QHSC--PSDCNNLGQCVSGRCICNEGYSGEDCSEV 623
+ C PS C G C+ G C+C+ GY GE C EV
Sbjct: 636 PMNQCIDPS-CGGHGSCIDGNCVCSAGYKGEHCEEV 670
Score = 41.6 bits (96), Expect = 0.009
Identities = 15/33 (45%), Positives = 22/33 (66%)
Query: 594 CPSDCNNLGQCVSGRCICNEGYSGEDCSEVSPP 626
CP +C+ G+CVSG C C G+ G DC++ + P
Sbjct: 576 CPRNCHGNGECVSGVCHCFPGFLGADCAKAACP 608
>gi|122937400 odz, odd Oz/ten-m homolog 3 [Homo sapiens]
Length = 2699
Score = 233 bits (595), Expect = 1e-60
Identities = 115/309 (37%), Positives = 158/309 (51%), Gaps = 24/309 (7%)
Query: 217 SQLACPSDCNDQGKCVNGVCICFEGYAGADCSREICPVPCSEEHGTCVDGLCVCHDGFAG 276
S + CP +C+ G+CV+G C CF G+ G DCSR CPV CS +G G C+C G+ G
Sbjct: 514 SVVECPRNCHGNGECVSGTCHCFPGFLGPDCSRAACPVLCSG-NGQYSKGRCLCFSGWKG 572
Query: 277 DDCNKPL--CLN-NCYNRGRCVENECVCDEGFTGEDCSELICPND-CFDRGRCINGTCYC 332
+C+ P C++ C RG C+ C C+ G+ GE C E C + C + G CI+G C+C
Sbjct: 573 TECDVPTTQCIDPQCGGRGICIMGSCACNSGYKGESCEEADCIDPGCSNHGVCIHGECHC 632
Query: 333 EEGFTGEDCG--KPTCPHACHTQGRC--EEGQCVCDEGFAGVDCSEKRCPADCHNRGRCV 388
G+ G +C K CP C G E G C CD + G DCS + C DC + G C+
Sbjct: 633 SPGWGGSNCEILKTMCPDQCSGHGTYLQESGSCTCDPNWTGPDCSNEICSVDCGSHGVCM 692
Query: 389 DGRCECDDGFTGADCGELKCPNGCSGHGRCVNGQCVCDEGYTGEDCSQLRCPNDCHSRGR 448
G C C++G+TG C + C C+ HG C +G+C C +G+ GE C+ CP C+S GR
Sbjct: 693 GGTCRCEEGWTGPACNQRACHPRCAEHGTCKDGKCECSQGWNGEHCTIEGCPGLCNSNGR 752
Query: 449 CVEGK----CVCEQGFKGYDCSDMSCPNDCHQHGRCVNGMCVCDDGYTGEDCRDRQC--P 502
C + CVC+ G++G C D C + DG DC D C
Sbjct: 753 CTLDQNGWHCVCQPGWRGAGC-------DVAMETLCTDSKDNEGDGLI--DCMDPDCCLQ 803
Query: 503 RDCSNRGLC 511
C N+ C
Sbjct: 804 SSCQNQPYC 812
Score = 223 bits (568), Expect = 2e-57
Identities = 106/305 (34%), Positives = 150/305 (49%), Gaps = 20/305 (6%)
Query: 346 CPHACHTQGRCEEGQCVCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECDDGFTGADCG- 404
CP CH G C G C C GF G DCS CP C G+ GRC C G+ G +C
Sbjct: 518 CPRNCHGNGECVSGTCHCFPGFLGPDCSRAACPVLCSGNGQYSKGRCLCFSGWKGTECDV 577
Query: 405 -ELKCPNG-CSGHGRCVNGQCVCDEGYTGEDCSQLRCPND-CHSRGRCVEGKCVCEQGFK 461
+C + C G G C+ G C C+ GY GE C + C + C + G C+ G+C C G+
Sbjct: 578 PTTQCIDPQCGGRGICIMGSCACNSGYKGESCEEADCIDPGCSNHGVCIHGECHCSPGWG 637
Query: 462 GYDCSDMS--CPNDCHQHGRCV--NGMCVCDDGYTGEDCRDRQCPRDCSNRGLCVDGQCV 517
G +C + CP+ C HG + +G C CD +TG DC + C DC + G+C+ G C
Sbjct: 638 GSNCEILKTMCPDQCSGHGTYLQESGSCTCDPNWTGPDCSNEICSVDCGSHGVCMGGTCR 697
Query: 518 CEDGFTGPDCAELSCPNDCHGQGRCVNGQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQ 577
CE+G+TGP C + +C C G C +G+C C +G+ G+ C + CP C+ GRC Q
Sbjct: 698 CEEGWTGPACNQRACHPRCAEHGTCKDGKCECSQGWNGEHCTIEGCPGLCNSNGRCTLDQ 757
Query: 578 ----CICHEGFTGLDCG---QHSCPSDCNNLG----QCVSGRCICNEGYSGED-CSEVSP 625
C+C G+ G C + C +N G C+ C + C +
Sbjct: 758 NGWHCVCQPGWRGAGCDVAMETLCTDSKDNEGDGLIDCMDPDCCLQSSCQNQPYCRGLPD 817
Query: 626 PKDLV 630
P+D++
Sbjct: 818 PQDII 822
Score = 221 bits (563), Expect = 6e-57
Identities = 109/305 (35%), Positives = 147/305 (48%), Gaps = 22/305 (7%)
Query: 189 ECPGNCHLRGRCIDGQCICDDGFTGEDCSQLACPSDCNDQGKCVNGVCICFEGYAGADCS 248
ECP NCH G C+ G C C GF G DCS+ ACP C+ G+ G C+CF G+ G +C
Sbjct: 517 ECPRNCHGNGECVSGTCHCFPGFLGPDCSRAACPVLCSGNGQYSKGRCLCFSGWKGTECD 576
Query: 249 --REICPVPCSEEHGTCVDGLCVCHDGFAGDDCNKPLCLN-NCYNRGRCVENECVCDEGF 305
C P G C+ G C C+ G+ G+ C + C++ C N G C+ EC C G+
Sbjct: 577 VPTTQCIDPQCGGRGICIMGSCACNSGYKGESCEEADCIDPGCSNHGVCIHGECHCSPGW 636
Query: 306 TGEDCSEL--ICPNDCFDRGRCI--NGTCYCEEGFTGEDCGKPTCPHACHTQGRCEEGQC 361
G +C L +CP+ C G + +G+C C+ +TG DC C C + G C G C
Sbjct: 637 GGSNCEILKTMCPDQCSGHGTYLQESGSCTCDPNWTGPDCSNEICSVDCGSHGVCMGGTC 696
Query: 362 VCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECDDGFTGADCGELKCPNGCSGHGRCV-- 419
C+EG+ G C+++ C C G C DG+CEC G+ G C CP C+ +GRC
Sbjct: 697 RCEEGWTGPACNQRACHPRCAEHGTCKDGKCECSQGWNGEHCTIEGCPGLCNSNGRCTLD 756
Query: 420 -NG-QCVCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCEQGFKGYDCSDMSC--PNDCH 475
NG CVC G+ G C D C + K +G DC D C + C
Sbjct: 757 QNGWHCVCQPGWRGAGC-------DVAMETLCTDSK--DNEGDGLIDCMDPDCCLQSSCQ 807
Query: 476 QHGRC 480
C
Sbjct: 808 NQPYC 812
Score = 201 bits (512), Expect = 5e-51
Identities = 103/305 (33%), Positives = 139/305 (45%), Gaps = 30/305 (9%)
Query: 161 CSGRGNFSTEGCGCVCEPGWKGPNCSEPECPGNCHLRGRCIDGQCICDDGFTGEDC---S 217
C G G + C C PG+ GP+CS CP C G+ G+C+C G+ G +C +
Sbjct: 522 CHGNGECVSGTCHCF--PGFLGPDCSRAACPVLCSGNGQYSKGRCLCFSGWKGTECDVPT 579
Query: 218 QLACPSDCNDQGKCVNGVCICFEGYAGADCSREICPVPCSEEHGTCVDGLCVCHDGFAGD 277
C +G C+ G C C GY G C C P HG C+ G C C G+ G
Sbjct: 580 TQCIDPQCGGRGICIMGSCACNSGYKGESCEEADCIDPGCSNHGVCIHGECHCSPGWGGS 639
Query: 278 DCN--KPLCLNNCYNRGRCVE--NECVCDEGFTGEDCSELICPNDCFDRGRCINGTCYCE 333
+C K +C + C G ++ C CD +TG DCS IC DC G C+ GTC CE
Sbjct: 640 NCEILKTMCPDQCSGHGTYLQESGSCTCDPNWTGPDCSNEICSVDCGSHGVCMGGTCRCE 699
Query: 334 EGFTGEDCGKPTCPHACHTQGRCEEGQCVCDEGFAGVDCSEKRCPADCHNRGRCV----D 389
EG+TG C + C C G C++G+C C +G+ G C+ + CP C++ GRC
Sbjct: 700 EGWTGPACNQRACHPRCAEHGTCKDGKCECSQGWNGEHCTIEGCPGLCNSNGRCTLDQNG 759
Query: 390 GRCECDDGFTGADCG---ELKCPNGCSGHG----RCVNGQCVCDEGYTGEDCSQLRCPND 442
C C G+ GA C E C + G C++ C C Q C N
Sbjct: 760 WHCVCQPGWRGAGCDVAMETLCTDSKDNEGDGLIDCMDPDC----------CLQSSCQNQ 809
Query: 443 CHSRG 447
+ RG
Sbjct: 810 PYCRG 814
Score = 181 bits (459), Expect = 7e-45
Identities = 98/277 (35%), Positives = 134/277 (48%), Gaps = 25/277 (9%)
Query: 139 QCTAGAGCC----LQPATGRLDTRPFCSGRGNFSTEGCGCVCEPGWKGPNCSEP--EC-P 191
+C +G C L P R CSG G +S C+C GWKG C P +C
Sbjct: 527 ECVSGTCHCFPGFLGPDCSRAACPVLCSGNGQYSKG--RCLCFSGWKGTECDVPTTQCID 584
Query: 192 GNCHLRGRCIDGQCICDDGFTGEDCSQLAC-PSDCNDQGKCVNGVCICFEGYAGADCS-- 248
C RG CI G C C+ G+ GE C + C C++ G C++G C C G+ G++C
Sbjct: 585 PQCGGRGICIMGSCACNSGYKGESCEEADCIDPGCSNHGVCIHGECHCSPGWGGSNCEIL 644
Query: 249 REICPVPCSEEHGTCV--DGLCVCHDGFAGDDCNKPLCLNNCYNRGRCVENECVCDEGFT 306
+ +CP CS HGT + G C C + G DC+ +C +C + G C+ C C+EG+T
Sbjct: 645 KTMCPDQCS-GHGTYLQESGSCTCDPNWTGPDCSNEICSVDCGSHGVCMGGTCRCEEGWT 703
Query: 307 GEDCSELICPNDCFDRGRCINGTCYCEEGFTGEDCGKPTCPHACHTQGRCEEGQ----CV 362
G C++ C C + G C +G C C +G+ GE C CP C++ GRC Q CV
Sbjct: 704 GPACNQRACHPRCAEHGTCKDGKCECSQGWNGEHCTIEGCPGLCNSNGRCTLDQNGWHCV 763
Query: 363 CDEGFAGVDCS---EKRCPADCHNRGRCVDGRCECDD 396
C G+ G C E C N G DG +C D
Sbjct: 764 CQPGWRGAGCDVAMETLCTDSKDNEG---DGLIDCMD 797
Score = 133 bits (335), Expect = 2e-30
Identities = 62/196 (31%), Positives = 86/196 (43%), Gaps = 39/196 (19%)
Query: 466 SDMSCPNDCHQHGRCVNGMCVCDDGYTGEDCRDRQCP----------------------- 502
S + CP +CH +G CV+G C C G+ G DC CP
Sbjct: 514 SVVECPRNCHGNGECVSGTCHCFPGFLGPDCSRAACPVLCSGNGQYSKGRCLCFSGWKGT 573
Query: 503 -----------RDCSNRGLCVDGQCVCEDGFTGPDCAELSCPN-DCHGQGRCVNGQCVCH 550
C RG+C+ G C C G+ G C E C + C G C++G+C C
Sbjct: 574 ECDVPTTQCIDPQCGGRGICIMGSCACNSGYKGESCEEADCIDPGCSNHGVCIHGECHCS 633
Query: 551 EGFMGKDCK--EQRCPSDCHGQGRCV--DGQCICHEGFTGLDCGQHSCPSDCNNLGQCVS 606
G+ G +C+ + CP C G G + G C C +TG DC C DC + G C+
Sbjct: 634 PGWGGSNCEILKTMCPDQCSGHGTYLQESGSCTCDPNWTGPDCSNEICSVDCGSHGVCMG 693
Query: 607 GRCICNEGYSGEDCSE 622
G C C EG++G C++
Sbjct: 694 GTCRCEEGWTGPACNQ 709
>gi|24041035 notch 2 preproprotein [Homo sapiens]
Length = 2471
Score = 231 bits (590), Expect = 5e-60
Identities = 192/593 (32%), Positives = 254/593 (42%), Gaps = 152/593 (25%)
Query: 171 GCGCVCEPGWKGPNCSEP--ECPGN-CHLRGRCIDG----QCICDDGFTG-------EDC 216
G C+C PG+KG +C EC N C G+C+D QC+C GFTG +DC
Sbjct: 477 GFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDC 536
Query: 217 SQLACPSDCNDQGKCV---NGV-CICFEGYAGADCSREI--C-PVPCSEEHGTCVDGL-- 267
S + C + KC+ NG C C G+ G C I C P PC HG C DG+
Sbjct: 537 SS----TPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPC--HHGQCQDGIDS 590
Query: 268 --CVCHDGFAGDDCNKPL--CLNN-CYNRGRCVE----NECVCDEGFTGEDCS---ELIC 315
C+C+ G+ G C+ + C ++ C N GRC++ +C C G +G +C +
Sbjct: 591 YTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCA 650
Query: 316 PNDCFDRGRCING----TCYCEEGFTGEDCGK---------------------------P 344
N C G C++G +C C GFTG+ C P
Sbjct: 651 SNPCI-HGICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICP 709
Query: 345 TCPH--ACHTQ-----------GRCEEG----QCVCDEGFAGVDCS--EKRCPAD-CHNR 384
PH +C++Q G C G +C+CD G+ G++C + C ++ C N
Sbjct: 710 EGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNG 769
Query: 385 GRC---VDG-RCECDDGFTGADCG---ELKCPNGCSGHGRCVNG----QCVCDEGYTGED 433
G C V+G RC C GF G +C + N C G C + C C YTG++
Sbjct: 770 GTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKN 829
Query: 434 CSQLRCP---NDCHSRGRCVEGK------CVCEQGFKGYDCS---DMSCPNDCHQHGRCV 481
C + P N C + C E C+C G++G C+ D C HG C
Sbjct: 830 CQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCH 889
Query: 482 NG----MCVCDDGYTGEDCR---DRQCPRDCSNRGLCVDG----QCVCEDGFTGPDCAE- 529
N MC C G++G DC D C N G C+DG C+C GFTG C
Sbjct: 890 NTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTD 949
Query: 530 ----LSCPNDCHGQGRC---VNGQ-CVCHEGFMGKDCKEQ--RCP-SDCHGQGRCVDG-- 576
LS P C G C VN C C GF G C+ C S C G CVDG
Sbjct: 950 MNECLSEP--CKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGIN 1007
Query: 577 --QCICHEGFTGLDCGQ--HSCPSD-CNNLGQCVSG----RCICNEGYSGEDC 620
C+C GFTG C + C S C N G CV G RC C GY+G++C
Sbjct: 1008 SFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNC 1060
Score = 226 bits (576), Expect = 2e-58
Identities = 187/620 (30%), Positives = 257/620 (41%), Gaps = 154/620 (24%)
Query: 146 CCLQPATGRLDTRPFCSGRGNFSTEGCGCVCEPGWKGPNCSE--PEC------PGN---- 193
C LQP C+ R G GCVC GW G +CSE +C PG+
Sbjct: 302 CLLQP--NACQNGGTCANRNG----GYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCID 355
Query: 194 -----------------CHLRGRCI---------------DGQ--CICDDGFTGEDCSQ- 218
CHL CI +GQ C C G+ G DC++
Sbjct: 356 RVASFSCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTED 415
Query: 219 -----LACPSDCNDQGKCVNG----VCICFEGYAGADCSREI--CPVPCSEEHGTCVDGL 267
+A + C GKCVN C C +GYAG C +I C + TC+D +
Sbjct: 416 VDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKI 475
Query: 268 ----CVCHDGFAGDDCNKPL--CLNN-CYNRGRCVEN----ECVCDEGFTG-------ED 309
C+C GF G C + C +N C N G+CV+ +C+C GFTG +D
Sbjct: 476 GGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDD 535
Query: 310 CSELICPN--DCFDRGRCING-TCYCEEGFTGEDCGK--PTC-PHACHTQGRCEEG---- 359
CS C N C D NG C C GFTG C + C P CH G+C++G
Sbjct: 536 CSSTPCLNGAKCIDHP---NGYECQCATGFTGVLCEENIDNCDPDPCH-HGQCQDGIDSY 591
Query: 360 QCVCDEGFAGVDCSEK--RC-PADCHNRGRCVD----GRCECDDGFTGADCGELK---CP 409
C+C+ G+ G CS++ C + C N GRC+D +C C G +G +C E+ C
Sbjct: 592 TCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNC-EINFDDCA 650
Query: 410 NGCSGHGRCVNG----QCVCDEGYTGEDCS---QLRCPNDCHSRGRCVEG----KCVCEQ 458
+ HG C++G CVC G+TG+ C+ N C C+ G +C+C +
Sbjct: 651 SNPCIHGICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPE 710
Query: 459 GFKGYDCSDM--SCPNDCHQHGRCVNGM----CVCDDGYTGEDC---RDRQCPRDCSNRG 509
G C C ++ HG C G+ C+CD G+ G +C ++ C N G
Sbjct: 711 GPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGG 770
Query: 510 LC---VDG-QCVCEDGFTGPDC---AELSCPNDCHGQGRCVNG----QCVCHEGFMGKDC 558
C V+G +C C+ GF G +C + N C QG C + C C + GK+C
Sbjct: 771 TCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNC 830
Query: 559 KEQRC---PSDCHGQGRCVDG------QCICHEGFTGLDCG---QHSCPSDCNNLGQC-- 604
+ P+ C C + C+C G+ G C C N G C
Sbjct: 831 QTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHN 890
Query: 605 --VSGRCICNEGYSGEDCSE 622
S C C G+SG DC E
Sbjct: 891 TQGSYMCECPPGFSGMDCEE 910
Score = 217 bits (552), Expect = 1e-55
Identities = 179/630 (28%), Positives = 249/630 (39%), Gaps = 150/630 (23%)
Query: 139 QCTAG-AGCCLQPATGRLDTRPFCSGRGNFSTEGCGCVCEPGWKGPNCSE---------- 187
QC G G + D P G+ + C+C PG+ G CS+
Sbjct: 557 QCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPC 616
Query: 188 ------------------------------PECPGNCHLRGRCIDG----QCICDDGFTG 213
+C N + G C+DG C+C GFTG
Sbjct: 617 LNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMDGINRYSCVCSPGFTG 676
Query: 214 EDCS---QLACPSDCNDQGKCVNGV----CICFEGYAGADC---SREICPVPCSEEHGTC 263
+ C+ + C C+NGV CIC EG C E PC HG C
Sbjct: 677 QRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCI--HGNC 734
Query: 264 VDGL----CVCHDGFAGDDC--NKPLCLNN-CYNRGRCVE----NECVCDEGFTGEDCSE 312
GL C+C G+ G +C +K CL+N C N G C C C +GF G +C
Sbjct: 735 TGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQV 794
Query: 313 LI---CPNDCFDRGRCING----TCYCEEGFTGEDCG---KPTCPHACHTQGRCEEG--- 359
I N C ++G C + TC+C +TG++C P P+ C C+E
Sbjct: 795 NIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNF 854
Query: 360 ---QCVCDEGFAGVDCS---EKRCPADCHNRGRCVDGR----CECDDGFTGADCGE--LK 407
C+C G+ G C+ ++ C N G C + + CEC GF+G DC E
Sbjct: 855 ESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDD 914
Query: 408 C-PNGCSGHGRCVNG----QCVCDEGYTGEDC--SQLRCPND-CHSRGRCVE----GKCV 455
C N C G C++G C+C G+TG+ C C ++ C + G C + C
Sbjct: 915 CLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCK 974
Query: 456 CEQGFKGYDCS---DMSCPNDCHQHGRCVNGM----CVCDDGYTGEDC--RDRQC-PRDC 505
C+ GF G C + + C G CV+G+ C+C G+TG C +C C
Sbjct: 975 CQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPC 1034
Query: 506 SNRGLCVDG----QCVCEDGFTGPDC---AELSCPNDCHGQGRCV----NGQCVCHEGFM 554
N G CVDG +C C G+TG +C L + C +G CV QC+C G+
Sbjct: 1035 LNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWA 1094
Query: 555 GKDCKEQRCPSD-------------CHGQGRCVDG----QCICHEGFTGLDCGQH--SCP 595
G C D C G C++ C C G+TG C + C
Sbjct: 1095 GAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECA 1154
Query: 596 SD-CNNLGQC---VSG-RCICNEGYSGEDC 620
S+ C + C + G RC C GY G +C
Sbjct: 1155 SNPCQHGATCSDFIGGYRCECVPGYQGVNC 1184
Score = 213 bits (541), Expect = 2e-54
Identities = 183/592 (30%), Positives = 237/592 (40%), Gaps = 118/592 (19%)
Query: 146 CCLQPATGRL--DTRPFCSGRGNFST--EGCG-CVCEPGWKGPNCSEPE-CPGN-CHLRG 198
CC PA D C G T G G C C G+ G C + C N C G
Sbjct: 18 CCAAPAHALQCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGG 77
Query: 199 RCI------DGQCICDDGFTGEDCSQLACPSDCNDQGKCVNG-----------VCICFEG 241
C+ C C GFTGEDC Q + C C+NG C C G
Sbjct: 78 TCVAQAMLGKATCRCASGFTGEDC-QYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVG 136
Query: 242 YAGADCS-REIC-PVPCSEEHGTCV----DGLCVCHDGFAGDDC----NKPLCLNNCYNR 291
+ G +C + C PC+ TC C C GF G C N+ +C +
Sbjct: 137 FTGKECQWTDACLSHPCA-NGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHG 195
Query: 292 GRCV----ENECVCDEGFTGEDCSEL---ICPNDCFDRGRC-----INGTCYCEEGFTGE 339
G C+ +C C +GFTG+ C L P+ C + G C C C GF G
Sbjct: 196 GTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGS 255
Query: 340 DCGK--PTCP-HACHTQGRCEEG----QCVCDEGFAGVDCSE--KRC---PADCHNRGRC 387
C + CP H C G C +G C C + G C+E C P C N G C
Sbjct: 256 TCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTC 315
Query: 388 VDGR----CECDDGFTGADCGE-------LKCPNGCSGHGRCVNGQCVCDEGYTGEDC-- 434
+ C C +G++G DC E C G + R + C+C EG G C
Sbjct: 316 ANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHL 375
Query: 435 SQLRCPNDCHSRGRC----VEGK--CVCEQGFKGYDCSD------MSCPNDCHQHGRCVN 482
N CH C + G+ C C QG+KG DC++ M+ N C G+CVN
Sbjct: 376 DDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVN 435
Query: 483 G----MCVCDDGYTGEDCR--DRQCPRD-CSNRGLCVDG----QCVCEDGFTGPDCAELS 531
C C GY G C +C D C N C+D C+C GF G C EL
Sbjct: 436 TDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHC-ELE 494
Query: 532 C----PNDCHGQGRCVNG----QCVCHEGFMGKDCK---EQRCPSDCHGQGRCVDG---- 576
N C G+CV+ QC+C GF G C+ + + C +C+D
Sbjct: 495 INECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGY 554
Query: 577 QCICHEGFTGLDCGQH--SCPSDCNNLGQCVSG----RCICNEGYSGEDCSE 622
+C C GFTG+ C ++ +C D + GQC G CICN GY G CS+
Sbjct: 555 ECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSD 606
Score = 199 bits (505), Expect = 3e-50
Identities = 173/583 (29%), Positives = 231/583 (39%), Gaps = 130/583 (22%)
Query: 161 CSGRGNFSTEGCGCVCEPGWKGPNCSEP--ECPGN-CHLRGRCIDGQ----CICDDGFTG 213
C NF E C+C PGW+G C+ EC C G C + Q C C GF+G
Sbjct: 848 CKESPNF--ESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSG 905
Query: 214 EDCSQ-----LACPSDCNDQGKCVNGV----CICFEGYAGADCS---REICPVPCSEEHG 261
DC + LA P C + G C++GV C+C G+ G C E PC + G
Sbjct: 906 MDCEEDIDDCLANP--CQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPC-KNGG 962
Query: 262 TCVDGL----CVCHDGFAGDDCNKPL--CL-NNCYNRGRCVEN----ECVCDEGFTGEDC 310
TC D + C C GF G C + C ++C+N G CV+ C+C GFTG C
Sbjct: 963 TCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFC 1022
Query: 311 SELI---CPNDCFDRGRCINGT----CYCEEGFTGEDCGKPT--CPHA-CHTQGRC---- 356
I + C + G C++G C C G+TG++C C + C +G C
Sbjct: 1023 LHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKK 1082
Query: 357 EEGQCVCDEGFAGVDCSEKRCPAD-------------CHNRGRCVDG----RCECDDGFT 399
E QC+C G+AG C D C + G C++ C+C G+T
Sbjct: 1083 AESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYT 1142
Query: 400 GADCGEL--KCPNGCSGHGRCVNG-----QCVCDEGYTGEDCSQL--RCPND-CHSRGRC 449
G+ C E +C + HG + +C C GY G +C C N C + G C
Sbjct: 1143 GSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTC 1202
Query: 450 VE----GKCVCEQGFKGYDCSDMSCPNDCHQHGRCVNG----------MCVCDDGYTGED 495
++ KC C G +G C + +DC + C+NG C C G+ GE
Sbjct: 1203 IDLVNHFKCSCPPGTRGLLCEENI--DDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGER 1260
Query: 496 CRD--RQC-PRDCSNRG------LCVDGQCVCEDGFTGPDCAEL--SCPN-DCHGQGRCV 543
C +C CS+ G L D CVC FTG C CP C G C
Sbjct: 1261 CEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCA 1320
Query: 544 NGQ-------CVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGF-------TGLDC 589
C C GF G RC S C GQ +C G+ H + DC
Sbjct: 1321 VASNMPDGFICRCPPGFSG-----ARCQSSC-GQVKCRKGEQCVHTASGPRCFCPSPRDC 1374
Query: 590 GQHSCPSDCNNLGQCVSGR------CICNEGYSGEDCSEVSPP 626
S C + G C R C C +SG C + P
Sbjct: 1375 ESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAP 1417
Score = 86.3 bits (212), Expect = 3e-16
Identities = 60/191 (31%), Positives = 80/191 (41%), Gaps = 39/191 (20%)
Query: 474 CHQHGRCVN-----GMCVCDDGYTGEDCRDRQ-CPRD-CSNRGLCV------DGQCVCED 520
C G CV G C C +G+ GE C+ R C ++ C N G CV C C
Sbjct: 35 CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCAS 94
Query: 521 GFTGPDCAELSCPNDCHGQGRCVNG-----------QCVCHEGFMGKDCK-EQRCPSD-C 567
GFTG DC + S + C C+NG +C C GF GK+C+ C S C
Sbjct: 95 GFTGEDC-QYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPC 153
Query: 568 HGQGRCV----DGQCICHEGFTGLDC----GQHSCPSDCNNLGQCV----SGRCICNEGY 615
C C C GFTG C + P C + G C+ S +C C +G+
Sbjct: 154 ANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGF 213
Query: 616 SGEDCSEVSPP 626
+G+ C + P
Sbjct: 214 TGQYCDSLYVP 224
Score = 50.8 bits (120), Expect = 1e-05
Identities = 49/207 (23%), Positives = 70/207 (33%), Gaps = 39/207 (18%)
Query: 170 EGCGCVCEPGWKGPNCSEPECPGNCHLRGRCIDG----QCICDDGFTGEDCSQLACPSDC 225
+G C C PG+ G C C +C+ +C C + DC S C
Sbjct: 1327 DGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCP---SPRDCESGCASSPC 1383
Query: 226 NDQGKCVNG------VCICFEGYAGADCSREICPVPCSEEHGTCVDGLCV--CHDGFAGD 277
G C C C ++G+ C E+ P S TC+ C DG +
Sbjct: 1384 QHGGSCHPQRQPPYYSCQCAPPFSGSRC--ELYTAPPSTPPATCLSQYCADKARDGVCDE 1441
Query: 278 DCNKPLCLNNCYNRGRCVENECV-CDE-----GFTGEDCSELICPNDC-FDRGRCING-- 328
CN C + + +EN C + C EL +C FD C
Sbjct: 1442 ACNSHACQWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTVECLFDNFECQGNSK 1501
Query: 329 TC-------------YCEEGFTGEDCG 342
TC +C++G E+CG
Sbjct: 1502 TCKYDKYCADHFKDNHCDQGCNSEECG 1528
>gi|21704279 jagged 2 isoform b precursor [Homo sapiens]
Length = 1200
Score = 228 bits (581), Expect = 5e-59
Identities = 189/609 (31%), Positives = 249/609 (40%), Gaps = 136/609 (22%)
Query: 143 GAGCCLQPATGRLDTRPFCSGRGNFSTEGCG----CVCEPGWKGPNCSE-PECPGNCHLR 197
G C+ G+ C N GC C C GW+G C E PG H
Sbjct: 227 GNKACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGRFCDECVPYPGCVH-- 284
Query: 198 GRCID-GQCICDDGFTG----EDCSQLACPSDCNDQGKCVNGV-----CICFEGYAGADC 247
G C++ QC C+ + G +D + C + G C+N C C +GY+G +C
Sbjct: 285 GSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNC 344
Query: 248 SR--EICPVPCSEEHGTCVD---GL-CVCHDGFAGDDCNKPL--CLNN-CYNRGRCVEN- 297
+ C G+C + G C C G++G C + C +N C G CV+
Sbjct: 345 EKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQV 404
Query: 298 ---ECVCDEGFTGEDCSELICPNDCFDRGRCING----------TCYCEEGFTGEDC--G 342
EC+C E + G C + NDC RG+C +G C C GF G C
Sbjct: 405 DGFECICPEQWVGATCQ--LDVNDC--RGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELE 460
Query: 343 KPTCPHA-CHTQGRCEE----GQCVCDEGFAGVDCS---EKRCPADCHNRGRCV----DG 390
+ C + CH+ G CE+ C C +GF+G C + P+ C N RC D
Sbjct: 461 RDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDY 520
Query: 391 RCECDDGFTGADCGELK--CPNG------------------------CSGHGRCV----- 419
C C D F G +C + CP G C HGRCV
Sbjct: 521 YCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGG 580
Query: 420 NGQCVCDEGYTGEDCSQ-----LRCPNDCHSRGRCVEG----KCVCEQGFKGYDCS---D 467
N C+CD G+TG C + L P C + G C++ +C C G++G C +
Sbjct: 581 NFSCICDSGFTGTYCHENIDDCLGQP--CRNGGTCIDEVDAFRCFCPSGWEGELCDTNPN 638
Query: 468 MSCPNDCHQHGRC---VNGM-CVCDDGYTGEDCRDRQCPRD---CSNRGLCVDG----QC 516
P+ CH GRC VN C CDDG+ G+ C R+ D CSN G C D +C
Sbjct: 639 DCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRC 698
Query: 517 VCEDGFTGPDCA---ELSC-PNDCHGQGRCVNG----QCVCHEGFMGKDCKEQR--C-PS 565
C G+ G CA SC PN C G CV C+C +G+ G+ C C P
Sbjct: 699 ACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPL 758
Query: 566 DCHGQGRCVDG----QCICHEGFTGLDC--GQHSCPSD-CNNLGQCVSG----RCICNEG 614
C+ G CVDG +C C GF G DC C S C CV RC C G
Sbjct: 759 PCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPG 818
Query: 615 YSGEDCSEV 623
+G C EV
Sbjct: 819 RAGPRCQEV 827
Score = 197 bits (501), Expect = 9e-50
Identities = 181/562 (32%), Positives = 228/562 (40%), Gaps = 118/562 (20%)
Query: 171 GCGCVCEPGWKGPNCS--EPECPGN-CHLRGRCIDG----QCICDDGFTGEDCSQL---A 220
G C C GW GP C+ EC N C G C+D +CIC + + G C QL
Sbjct: 368 GFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATC-QLDVND 426
Query: 221 CPSDCNDQGKC---VNGV-CICFEGYAGADC--SREICPVPCSEEHGTC---VDGL-CVC 270
C C G C VNG C+C G+ G C R+ C G C DG C C
Sbjct: 427 CRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFHCHC 486
Query: 271 HDGFAGDDCNKPLCL---NNCYNRGRCVENE----CVCDEGFTGEDCSELICPNDCFDRG 323
GF+G C + L + C N RC E C C + F G++CS R
Sbjct: 487 PQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCS--------VPRE 538
Query: 324 RCINGTCYCEEGFTGEDCGKPTCP-----HACHTQGRCEEG-----QCVCDEGFAGVDCS 373
C G C +G G D G P P C GRC C+CD GF G C
Sbjct: 539 PCPGGACRVIDG-CGSDAG-PGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCH 596
Query: 374 EK--RCPAD-CHNRGRCVDG----RCECDDGFTG--ADCGELKC-PNGCSGHGRC---VN 420
E C C N G C+D RC C G+ G D C P+ C GRC VN
Sbjct: 597 ENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVN 656
Query: 421 G-QCVCDEGYTGEDCSQLRCPND---CHSRGRCVEG----KCVCEQGFKGYDCS---DMS 469
C CD+G+ G+ C D C + G C + +C C G+KG C+ + S
Sbjct: 657 DFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSS 716
Query: 470 C-PNDCHQHGRCVNG----MCVCDDGYTGEDC--RDRQC-PRDCSNRGLCVDG----QCV 517
C PN C G CV C+C DG+ G C C P C N G+CVDG +C
Sbjct: 717 CLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCE 776
Query: 518 CEDGFTGPDC---AELSCPNDCHGQGRCV---NG-QCVCHEGFMGKDCKE-----QRCPS 565
C GF GPDC + + C CV NG +C C G G C+E + C S
Sbjct: 777 CAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCWS 836
Query: 566 -------------DCHGQGRCVDGQCICHEGFTG----LDCGQHSCPSDCNNLGQ-CVS- 606
DC+ RC+DG+ C + + G L GQ S LGQ C+
Sbjct: 837 RGTPFPHGSSWVEDCN-SCRCLDGRRDCSKVWCGWKPCLLAGQPEALSAQCPLGQRCLEK 895
Query: 607 --GRCICNEGYSGEDCSEVSPP 626
G+C+ + +C PP
Sbjct: 896 APGQCLRPPCEAWGECGAEEPP 917
Score = 183 bits (465), Expect = 1e-45
Identities = 151/528 (28%), Positives = 208/528 (39%), Gaps = 128/528 (24%)
Query: 207 CDDGFTGEDCSQLACPSD-------CNDQGKCVNGVCICFEGYAGADCSREICPVPCSEE 259
CD+ + C++ P + C+ G C +G+ G +C +C C+
Sbjct: 198 CDENYYSATCNKFCRPRNDFFGHYTCDQYGNKA-----CMDGWMGKECKEAVCKQGCNLL 252
Query: 260 HGTC-VDGLCVCHDGFAGDDCNKPLCLNNCYNRGRCVEN-ECVCDEGFTGEDCSELICPN 317
HG C V G C C G+ G C++ + C + G CVE +C C+ + G L+C
Sbjct: 253 HGGCTVPGECRCSYGWQGRFCDECVPYPGCVH-GSCVEPWQCNCETNWGG-----LLCDK 306
Query: 318 D---------CFDRGRCING-----TCYCEEGFTGEDCGKPTCPHACHTQ-----GRCEE 358
D C + G CIN C C +G++G +C K HAC + G C E
Sbjct: 307 DLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEK--AEHACTSNPCANGGSCHE 364
Query: 359 ----GQCVCDEGFAGVDCS---EKRCPADCHNRGRCVDG----RCECDDGFTGADC--GE 405
+C C G++G C+ ++ C G CVD C C + + GA C
Sbjct: 365 VPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDV 424
Query: 406 LKCPNGCSGHGRC---VNG-QCVCDEGYTGEDCSQLR---CPNDCHSRGRCVE----GKC 454
C C G C VNG QCVC G+ G C R + CHS G C + C
Sbjct: 425 NDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFHC 484
Query: 455 VCEQGFKGYDCS---DMSCPNDCHQHGRCVN----GMCVCDDGYTGEDCR--DRQCPRD- 504
C QGF G C D+ P+ C RC N C C D + G++C CP
Sbjct: 485 HCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGA 544
Query: 505 -----------------------CSNRGLCV-----DGQCVCEDGFTGPDCAELSCPNDC 536
C G CV + C+C+ GFTG C E +DC
Sbjct: 545 CRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENI--DDC 602
Query: 537 HGQ-----GRCVNG----QCVCHEGFMGKDC---KEQRCPSDCHGQGRCV----DGQCIC 580
GQ G C++ +C C G+ G+ C P CH +GRC D C C
Sbjct: 603 LGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCAC 662
Query: 581 HEGFTGLDCGQHSCPSD---CNNLGQCVSG----RCICNEGYSGEDCS 621
+G+ G C D C+N G C RC C G+ G C+
Sbjct: 663 DDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCA 710
Score = 131 bits (330), Expect = 6e-30
Identities = 143/480 (29%), Positives = 183/480 (38%), Gaps = 107/480 (22%)
Query: 170 EGCGCVCEPGWKGPNCSEPE--C-PGNCHLRGRCI----DGQCICDDGFTGEDCSQL--- 219
+G C C G+ GP C C P C RC D C C D F G++CS
Sbjct: 480 DGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREP 539
Query: 220 ----------ACPSD-------------CNDQGKCV-----NGVCICFEGYAGADCSREI 251
C SD C G+CV N CIC G+ G C I
Sbjct: 540 CPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENI 599
Query: 252 CPV---PCSEEHGTCVDGL----CVCHDGFAGDDC--NKPLCLNN-CYNRGRCVE--NE- 298
PC GTC+D + C C G+ G+ C N CL + C++RGRC + N+
Sbjct: 600 DDCLGQPC-RNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDF 658
Query: 299 -CVCDEGFTGE-------DCSELICPND--CFDRGRCINGTCYCEEGFTGEDCG---KPT 345
C CD+G+ G+ C C N C+D G C C G+ G C +
Sbjct: 659 YCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFR--CACPPGWKGSTCAVAKNSS 716
Query: 346 C-PHACHTQGRCEEG----QCVCDEGFAGVDCSEKR--C-PADCHNRGRCVDG----RCE 393
C P+ C G C C+C +G+ G C+ C P C+N G CVDG RCE
Sbjct: 717 CLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCE 776
Query: 394 CDDGFTGADC--GELKCPNG-CSGHGRCV---NG-QCVCDEGYTGEDCSQ-LRCPNDCHS 445
C GF G DC +C + C+ CV NG +C C G G C + + C S
Sbjct: 777 CAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCWS 836
Query: 446 RG-------RCVE--GKCVCEQGFKGYDCSDMSCP-NDCHQHGRCVNGMCVCDDGYTGED 495
RG VE C C G + DCS + C C G+ C G +
Sbjct: 837 RGTPFPHGSSWVEDCNSCRCLDGRR--DCSKVWCGWKPCLLAGQPEALSAQCPLGQRCLE 894
Query: 496 CRDRQCPR-DCSNRGLC-----VDGQCVCEDGFTGPDCAELSC--PNDCHGQGRCVNGQC 547
QC R C G C C+ G +CA L+ D QG V C
Sbjct: 895 KAPGQCLRPPCEAWGECGAEEPPSTPCLPRSGHLDNNCARLTLHFNRDHVPQGTTVGAIC 954
Score = 94.4 bits (233), Expect = 1e-18
Identities = 99/337 (29%), Positives = 131/337 (38%), Gaps = 75/337 (22%)
Query: 130 ENLVSSLREQCTAGAGC--------CLQPA--TGRL-DTRPF------CSGRGNFS--TE 170
EN+ L + C G C C P+ G L DT P C RG
Sbjct: 597 ENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVN 656
Query: 171 GCGCVCEPGWKGPNC--SEPECPG-NCHLRGRCIDG----QCICDDGFTGEDC----SQL 219
C C+ GWKG C E +C C G C D +C C G+ G C +
Sbjct: 657 DFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSS 716
Query: 220 ACPSDCNDQGKCVNG----VCICFEGYAGADC---SREICPVPCSEEHGTCVDGL----C 268
P+ C + G CV CIC +G+ G C + + P+PC G CVDG+ C
Sbjct: 717 CLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPC-YNGGICVDGVNWFRC 775
Query: 269 VCHDGFAGDDC--NKPLCLNN-CYNRGRCVEN----ECVCDEGFTGEDCSELI-CPNDCF 320
C GFAG DC N C ++ C CV+ C C G G C E+I C+
Sbjct: 776 ECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCW 835
Query: 321 DRG----------------RCINGTCYCEEGFTG-EDC---GKPTCPHA-CHTQGRCEE- 358
RG RC++G C + + G + C G+P A C RC E
Sbjct: 836 SRGTPFPHGSSWVEDCNSCRCLDGRRDCSKVWCGWKPCLLAGQPEALSAQCPLGQRCLEK 895
Query: 359 --GQCVCDEGFAGVDCSEKRCPA-DCHNRGRCVDGRC 392
GQC+ A +C + P+ C R +D C
Sbjct: 896 APGQCLRPPCEAWGECGAEEPPSTPCLPRSGHLDNNC 932
Score = 58.9 bits (141), Expect = 5e-08
Identities = 45/149 (30%), Positives = 61/149 (40%), Gaps = 44/149 (29%)
Query: 518 CEDGFTGPDCAELSCP-NDCHGQGRCVN-GQCVCHEGFMGKDCKEQRCPSDC---HG--- 569
C++ + C + P ND G C G C +G+MGK+CKE C C HG
Sbjct: 198 CDENYYSATCNKFCRPRNDFFGHYTCDQYGNKACMDGWMGKECKEAVCKQGCNLLHGGCT 257
Query: 570 -----------QGR----------CVDGQCI------CHEGFTGLDCGQ--HSCPS--DC 598
QGR CV G C+ C + GL C + + C S C
Sbjct: 258 VPGECRCSYGWQGRFCDECVPYPGCVHGSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPC 317
Query: 599 NNLGQCVSG-----RCICNEGYSGEDCSE 622
N G C++ RC C +GYSG +C +
Sbjct: 318 TNGGTCINAEPDQYRCTCPDGYSGRNCEK 346
Score = 43.5 bits (101), Expect = 0.002
Identities = 26/81 (32%), Positives = 35/81 (43%), Gaps = 4/81 (4%)
Query: 549 CHEGFMGKDCKEQRCP-SDCHGQGRCVD-GQCICHEGFTGLDCGQHSCPSDCNNL--GQC 604
C E + C + P +D G C G C +G+ G +C + C CN L G
Sbjct: 198 CDENYYSATCNKFCRPRNDFFGHYTCDQYGNKACMDGWMGKECKEAVCKQGCNLLHGGCT 257
Query: 605 VSGRCICNEGYSGEDCSEVSP 625
V G C C+ G+ G C E P
Sbjct: 258 VPGECRCSYGWQGRFCDECVP 278
>gi|4557679 jagged 1 precursor [Homo sapiens]
Length = 1218
Score = 226 bits (576), Expect = 2e-58
Identities = 180/577 (31%), Positives = 242/577 (41%), Gaps = 109/577 (18%)
Query: 174 CVCEPGWKGPNC--SEPECPGN-CHLRGRC----IDGQCICDDGFTGEDCSQL---ACPS 223
C C G+ GPNC +E C + CH RG C + +C C G+TG CS P+
Sbjct: 322 CSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPN 381
Query: 224 DCNDQGKC---VNGV-CICFEGYAGADC---SREICPVPCSEEHGT---CVDGLCVCHDG 273
+C+ G C VNG C+C + G C + E PC C C G
Sbjct: 382 NCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPG 441
Query: 274 FAGDDCNKPL--CLNNCYNRGRCVE----NECVCDEGFTGEDCSELI---CPNDCFDRGR 324
+ G +C+ + CL C N C + C+C G+ G+ C I N C + G
Sbjct: 442 WMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGH 501
Query: 325 CINGT----CYCEEGFTG-------EDCGKPTCPHACHTQGRCEEGQCVCDEGFAGVDCS 373
C N C C GF+G + C C + R + C C E + G +CS
Sbjct: 502 CQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCS 561
Query: 374 EKRCPADCHNRGRCVDGRCECDDGFTGADCGELKCPNG--------CSGHGRCVNGQ--- 422
H + C CE D T A P G C HG+C +
Sbjct: 562 --------HLKDHCRTTPCEVIDSCTVAMASN-DTPEGVRYISSNVCGPHGKCKSQSGGK 612
Query: 423 --CVCDEGYTGEDCSQL--RCP-NDCHSRGRCVEG----KCVCEQGFKGYDC----SDMS 469
C C++G+TG C + C N C + G C++G KC+C G++G C +D S
Sbjct: 613 FTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCS 672
Query: 470 CPNDCHQHGRC---VNGM-CVCDDGYTGEDC--RDRQCPR-DCSNRGLCVDG----QCVC 518
N CH G C VN C C +G+ G+ C RD QC C+N G C D +C+C
Sbjct: 673 -QNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMC 731
Query: 519 EDGFTGPDC---AELSC-PNDCHGQGRCV-NGQ---CVCHEGFMGKDCKEQR---CPSDC 567
G+ G C SC PN CH G CV NG+ CVC EG+ G C + P C
Sbjct: 732 PGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPC 791
Query: 568 HGQGRCVDG----QCICHEGFTGLDC--GQHSCPSD-CNNLGQCVSG----RCICNEGYS 616
+ G CVDG +C C GF G DC + C S C CV RC+C G+S
Sbjct: 792 YNSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHS 851
Query: 617 GEDCSEVSPPKDLVVTEVTEETVNLAWDNEMRVTEYL 653
G C EVS + + V + WD++ + L
Sbjct: 852 GAKCQEVSGRPCITMGSVIPD--GAKWDDDCNTCQCL 886
Score = 211 bits (536), Expect = 8e-54
Identities = 173/572 (30%), Positives = 238/572 (41%), Gaps = 133/572 (23%)
Query: 161 CSGRGNFSTEGCG--CVCEPGWKGPNCSE--PEC-PGNCHLRGRCID----GQCICDDGF 211
C RG+ G C C PGW GP CS +C P NC G C D +C+C +
Sbjct: 345 CHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQW 404
Query: 212 TGEDCSQLA--CPS-DCNDQGKCVNGV----CICFEGYAGADCSREI--CPVPCSEEHGT 262
TG+ C A C + C + C N + C C G+ G +C I C C + +
Sbjct: 405 TGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQND-AS 463
Query: 263 CVDGL----CVCHDGFAGDDCNKPL--CLNN-CYNRGRCVEN----ECVCDEGFTGEDCS 311
C D + C+C G+AGD C + + C +N C N G C +C+C GF+G C
Sbjct: 464 CRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQ 523
Query: 312 ---ELICPNDCFDRGRCINGT----CYCEEGFTGEDCG--KPTC---------------- 346
+ PN C + +C N C C E + G++C K C
Sbjct: 524 LDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMA 583
Query: 347 ------------PHACHTQGRCEEGQ-----CVCDEGFAGVDCSE--KRCPAD-CHNRGR 386
+ C G+C+ C C++GF G C E C ++ C N G
Sbjct: 584 SNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGT 643
Query: 387 CVDG----RCECDDGFTGA-------DCGELKCPNGCSGHGRCVNGQCVCDEGYTGEDCS 435
C+DG +C C DG+ GA DC + C NG + + C C G+ G+ C
Sbjct: 644 CIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCH 703
Query: 436 QLRCPND---CHSRGRCVEG----KCVCEQGFKGYDCS---DMSC-PNDCHQHGRC-VNG 483
D C++ G C + KC+C G++G C+ + SC PN CH G C VNG
Sbjct: 704 SRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNG 763
Query: 484 ---MCVCDDGYTGEDCRDRQ---CPRDCSNRGLCVDG----QCVCEDGFTGPDC---AEL 530
CVC +G+ G C P C N G CVDG +C C GF GPDC
Sbjct: 764 ESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPGFAGPDCRININE 823
Query: 531 SCPNDCHGQGRCV---NG-QCVCHEGFMGKDCKEQRCPSDCHGQGR-CVDGQCICHEGFT 585
+ C CV NG +CVC G G C+E GR C+ + +G
Sbjct: 824 CQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQEV--------SGRPCITMGSVIPDGAK 875
Query: 586 GLDCGQHSCPSDCNNLGQCVSGRCICNEGYSG 617
D DCN QC++GR C++ + G
Sbjct: 876 WDD--------DCNTC-QCLNGRIACSKVWCG 898
Score = 206 bits (524), Expect = 2e-52
Identities = 175/596 (29%), Positives = 247/596 (41%), Gaps = 146/596 (24%)
Query: 160 FCSGRGNF-----STEGCGCVCEPGWKGPNCSEPECPGNCHLR-GRC-IDGQCICDDGFT 212
FC R +F + C GW GP C+ C C + G C + G C C G+
Sbjct: 199 FCRPRDDFFGHYACDQNGNKTCMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQ 258
Query: 213 GEDCSQLACPSDCNDQGKCVNGV------CICFEGYAGADCSREI--CPV--PCSEEHGT 262
G C + C CV+G+ C+C + G C +++ C PC GT
Sbjct: 259 GLYCDK------CIPHPGCVHGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCL-NGGT 311
Query: 263 CVDG-----LCVCHDGFAGDDCN--KPLCLNN-CYNRGRCVEN----ECVCDEGFTGEDC 310
C + C C +G++G +C + CL++ C+NRG C E EC C G+TG C
Sbjct: 312 CSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTC 371
Query: 311 SELI---CPNDCFDRGRC---ING-TCYCEEGFTGEDC--------GKPTCPHACHTQGR 355
S I PN+C G C +NG C C +TG+ C KP C +A +
Sbjct: 372 STNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKP-CVNAKSCKNL 430
Query: 356 CEEGQCVCDEGFAGVDC--SEKRCPADCHNRGRCVD----GRCECDDGFTGADCG---EL 406
C C G+ G +C + C C N C D RC C G+ G C +
Sbjct: 431 IASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDE 490
Query: 407 KCPNGCSGHGRCVNG----QCVCDEGYTGEDCSQLRC----PNDCHSRGRCVEGK----C 454
N C G C N QC+C G++G C QL PN C + +C C
Sbjct: 491 CASNPCLNGGHCQNEINRFQCLCPTGFSGNLC-QLDIDYCEPNPCQNGAQCYNRASDYFC 549
Query: 455 VCEQGFKGYDCSDM-------------SC-----------------PNDCHQHGRCVNG- 483
C + ++G +CS + SC N C HG+C +
Sbjct: 550 KCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQS 609
Query: 484 ----MCVCDDGYTGEDCRD--RQCPRD-CSNRGLCVDG----QCVCEDGFTGP------- 525
C C+ G+TG C + C + C N G C+DG +C+C DG+ G
Sbjct: 610 GGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNIN 669
Query: 526 DCAELSCPNDCHGQGRC---VNG-QCVCHEGFMGKDC--KEQRC-PSDCHGQGRCVDG-- 576
DC++ N CH G C VN C C G+ GK C ++ +C + C+ G C D
Sbjct: 670 DCSQ----NPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGD 725
Query: 577 --QCICHEGFTGLDCG---QHSC-PSDCNNLGQCV----SGRCICNEGYSGEDCSE 622
+C+C G+ G C SC P+ C+N G CV S C+C EG+ G C++
Sbjct: 726 AFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQ 781
Score = 187 bits (476), Expect = 8e-47
Identities = 156/510 (30%), Positives = 219/510 (42%), Gaps = 128/510 (25%)
Query: 207 CDDGFTGEDCSQLACPSD-------CNDQGKCVNGVCICFEGYAGADCSREICPVPCSEE 259
CDD + G C++ P D C+ NG C EG+ G +C+R IC CS +
Sbjct: 187 CDDYYYGFGCNKFCRPRDDFFGHYACDQ-----NGNKTCMEGWMGPECNRAICRQGCSPK 241
Query: 260 HGTC-VDGLCVCHDGFAGDDCNKPLCLNNCYNRGRCVEN-ECVCDEGFTGEDCSELICPN 317
HG+C + G C C G+ G C+K + C + G C E +C+C+ + G+ C + + N
Sbjct: 242 HGSCKLPGDCRCQYGWQGLYCDKCIPHPGCVH-GICNEPWQCLCETNWGGQLCDKDL--N 298
Query: 318 DCFDRGRCIN-GTCYCEEGFTGEDCGKPTCPHACHTQGRCEEGQCVCDEGFAGVDC--SE 374
C C+N GTC TG D + +CP EG++G +C +E
Sbjct: 299 YCGTHQPCLNGGTC----SNTGPDKYQCSCP-----------------EGYSGPNCEIAE 337
Query: 375 KRCPAD-CHNRGRCVDG----RCECDDGFTGADCG---ELKCPNGCSGHGRC---VNG-Q 422
C +D CHNRG C + CEC G+TG C + PN CS G C VNG +
Sbjct: 338 HACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFK 397
Query: 423 CVCDEGYTGEDCSQLRCPNDCHSRGRCVEGK----------CVCEQGFKGYDC--SDMSC 470
CVC +TG+ C QL N+C ++ CV K C C G+ G +C + C
Sbjct: 398 CVCPPQWTGKTC-QLDA-NECEAK-PCVNAKSCKNLIASYYCDCLPGWMGQNCDININDC 454
Query: 471 PNDCHQHGRC---VNG-MCVCDDGYTGEDCR---DRQCPRDCSNRGLCVDG----QCVCE 519
C C VNG C+C GY G+ C D C N G C + QC+C
Sbjct: 455 LGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCP 514
Query: 520 DGFTGPDC---AELSCPNDCHGQGRCVNGQ----CVCHEGFMGKDCK--EQRCPSD---- 566
GF+G C + PN C +C N C C E + GK+C + C +
Sbjct: 515 TGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEV 574
Query: 567 ------------------------CHGQGRCVDGQ-----CICHEGFTGLDCGQ--HSCP 595
C G+C C C++GFTG C + + C
Sbjct: 575 IDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDCE 634
Query: 596 SD-CNNLGQCVSG----RCICNEGYSGEDC 620
S+ C N G C+ G +CIC++G+ G C
Sbjct: 635 SNPCRNGGTCIDGVNSYKCICSDGWEGAYC 664
>gi|169790825 odz, odd Oz/ten-m homolog 4 [Homo sapiens]
Length = 2769
Score = 223 bits (568), Expect = 2e-57
Identities = 114/302 (37%), Positives = 153/302 (50%), Gaps = 31/302 (10%)
Query: 221 CPSDCNDQGKCVNGVCICFEGYAGADCSREICPVPCSEEHGTCVDGLCVCHDGFAGDDCN 280
CPS+C G C++G C CF G+ G DC R CPV CS +G + G C+CH G+ G +C+
Sbjct: 566 CPSNCYGNGDCISGTCHCFLGFLGPDCGRASCPVLCSG-NGQYMKGRCLCHSGWKGAECD 624
Query: 281 KPL--CLN-NCYNRGRCVENECVCDEGFTGEDCSELICPND-CFDRGRCINGTCYCEEGF 336
P C++ C N G C+ C+C+ G+ GE C E+ C + C RG C+ G C+C G+
Sbjct: 625 VPTNQCIDVACSNHGTCITGTCICNPGYKGESCEEVDCMDPTCSGRGVCVRGECHCSVGW 684
Query: 337 TGEDCGKP--TCPHACHTQGRC--EEGQCVCDEGFAGVDCSEKRCPADCHNRGRCVDGRC 392
G +C P TC C G + G C CD + G DCS + C ADC G CV G C
Sbjct: 685 GGTNCETPRATCLDQCSGHGTFLPDTGLCSCDPSWTGHDCSIEICAADCGGHGVCVGGTC 744
Query: 393 ECDDGFTGADCGELKCPNGCSGHGRCVNGQCVCDEGYTGEDCS---------QLRCPNDC 443
C+DG+ GA C + C C+ HG C +G+C C G+ GE C+ + CP C
Sbjct: 745 RCEDGWMGAACDQRACHPRCAEHGTCRDGKCECSPGWNGEHCTIAHYLDRVVKEGCPGLC 804
Query: 444 HSRGRCV----EGKCVCEQGFKGYDCSDMSCPNDCHQHGRCVNGMCVCDDGYTGEDCRDR 499
+ GRC CVC+ G++G C D S C G +DG DC D
Sbjct: 805 NGNGRCTLDLNGWHCVCQLGWRGAGC-DTSMETAC--------GDSKDNDGDGLVDCMDP 855
Query: 500 QC 501
C
Sbjct: 856 DC 857
Score = 222 bits (565), Expect = 4e-57
Identities = 112/299 (37%), Positives = 151/299 (50%), Gaps = 32/299 (10%)
Query: 315 CPNDCFDRGRCINGTCYCEEGFTGEDCGKPTCPHACHTQGRCEEGQCVCDEGFAGVDCS- 373
CP++C+ G CI+GTC+C GF G DCG+ +CP C G+ +G+C+C G+ G +C
Sbjct: 566 CPSNCYGNGDCISGTCHCFLGFLGPDCGRASCPVLCSGNGQYMKGRCLCHSGWKGAECDV 625
Query: 374 -EKRC-PADCHNRGRCVDGRCECDDGFTGADCGELKCPNG-CSGHGRCVNGQCVCDEGYT 430
+C C N G C+ G C C+ G+ G C E+ C + CSG G CV G+C C G+
Sbjct: 626 PTNQCIDVACSNHGTCITGTCICNPGYKGESCEEVDCMDPTCSGRGVCVRGECHCSVGWG 685
Query: 431 GEDCSQLR--CPNDCHSRGRCVE--GKCVCEQGFKGYDCSDMSCPNDCHQHGRCVNGMCV 486
G +C R C + C G + G C C+ + G+DCS C DC HG CV G C
Sbjct: 686 GTNCETPRATCLDQCSGHGTFLPDTGLCSCDPSWTGHDCSIEICAADCGGHGVCVGGTCR 745
Query: 487 CDDGYTGEDCRDRQCPRDCSNRGLCVDGQCVCEDGFTGPDC---------AELSCPNDCH 537
C+DG+ G C R C C+ G C DG+C C G+ G C + CP C+
Sbjct: 746 CEDGWMGAACDQRACHPRCAEHGTCRDGKCECSPGWNGEHCTIAHYLDRVVKEGCPGLCN 805
Query: 538 GQGRC---VNG-QCVCHEGFMGKDC---KEQRC----PSDCHGQGRCVDGQC----ICH 581
G GRC +NG CVC G+ G C E C +D G C+D C +CH
Sbjct: 806 GNGRCTLDLNGWHCVCQLGWRGAGCDTSMETACGDSKDNDGDGLVDCMDPDCCLQPLCH 864
Score = 208 bits (530), Expect = 4e-53
Identities = 111/322 (34%), Positives = 152/322 (47%), Gaps = 34/322 (10%)
Query: 186 SEPECPGNCHLRGRCIDGQCICDDGFTGEDCSQLACPSDCNDQGKCVNGVCICFEGYAGA 245
S CP NC+ G CI G C C GF G DC + +CP C+ G+ + G C+C G+ GA
Sbjct: 562 SVDNCPSNCYGNGDCISGTCHCFLGFLGPDCGRASCPVLCSGNGQYMKGRCLCHSGWKGA 621
Query: 246 DC---SREICPVPCSEEHGTCVDGLCVCHDGFAGDDCNKPLCLN-NCYNRGRCVENECVC 301
+C + + V CS HGTC+ G C+C+ G+ G+ C + C++ C RG CV EC C
Sbjct: 622 ECDVPTNQCIDVACS-NHGTCITGTCICNPGYKGESCEEVDCMDPTCSGRGVCVRGECHC 680
Query: 302 DEGFTGEDCS--ELICPNDCFDRGRCI--NGTCYCEEGFTGEDCGKPTCPHACHTQGRCE 357
G+ G +C C + C G + G C C+ +TG DC C C G C
Sbjct: 681 SVGWGGTNCETPRATCLDQCSGHGTFLPDTGLCSCDPSWTGHDCSIEICAADCGGHGVCV 740
Query: 358 EGQCVCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECDDGFTGADCG---------ELKC 408
G C C++G+ G C ++ C C G C DG+CEC G+ G C + C
Sbjct: 741 GGTCRCEDGWMGAACDQRACHPRCAEHGTCRDGKCECSPGWNGEHCTIAHYLDRVVKEGC 800
Query: 409 PNGCSGHGRC---VNG-QCVCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCEQGFKGYD 464
P C+G+GRC +NG CVC G+ G C D C + K G D
Sbjct: 801 PGLCNGNGRCTLDLNGWHCVCQLGWRGAGC-------DTSMETACGDSKDNDGDGL--VD 851
Query: 465 CSDMSCPNDCHQHGRCVNGMCV 486
C D C C Q +N +C+
Sbjct: 852 CMDPDC---CLQPLCHINPLCL 870
Score = 202 bits (515), Expect = 2e-51
Identities = 97/269 (36%), Positives = 133/269 (49%), Gaps = 21/269 (7%)
Query: 373 SEKRCPADCHNRGRCVDGRCECDDGFTGADCGELKCPNGCSGHGRCVNGQCVCDEGYTGE 432
S CP++C+ G C+ G C C GF G DCG CP CSG+G+ + G+C+C G+ G
Sbjct: 562 SVDNCPSNCYGNGDCISGTCHCFLGFLGPDCGRASCPVLCSGNGQYMKGRCLCHSGWKGA 621
Query: 433 DCS--QLRCPN-DCHSRGRCVEGKCVCEQGFKGYDCSDMSCPN-DCHQHGRCVNGMCVCD 488
+C +C + C + G C+ G C+C G+KG C ++ C + C G CV G C C
Sbjct: 622 ECDVPTNQCIDVACSNHGTCITGTCICNPGYKGESCEEVDCMDPTCSGRGVCVRGECHCS 681
Query: 489 DGYTGEDCRDRQ--CPRDCSNRG--LCVDGQCVCEDGFTGPDCAELSCPNDCHGQGRCVN 544
G+ G +C + C CS G L G C C+ +TG DC+ C DC G G CV
Sbjct: 682 VGWGGTNCETPRATCLDQCSGHGTFLPDTGLCSCDPSWTGHDCSIEICAADCGGHGVCVG 741
Query: 545 GQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLDCG---------QHSCP 595
G C C +G+MG C ++ C C G C DG+C C G+ G C + CP
Sbjct: 742 GTCRCEDGWMGAACDQRACHPRCAEHGTCRDGKCECSPGWNGEHCTIAHYLDRVVKEGCP 801
Query: 596 SDCNNLGQCV----SGRCICNEGYSGEDC 620
CN G+C C+C G+ G C
Sbjct: 802 GLCNGNGRCTLDLNGWHCVCQLGWRGAGC 830
Score = 196 bits (499), Expect = 2e-49
Identities = 90/238 (37%), Positives = 129/238 (54%), Gaps = 17/238 (7%)
Query: 408 CPNGCSGHGRCVNGQCVCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCEQGFKGYDCS- 466
CP+ C G+G C++G C C G+ G DC + CP C G+ ++G+C+C G+KG +C
Sbjct: 566 CPSNCYGNGDCISGTCHCFLGFLGPDCGRASCPVLCSGNGQYMKGRCLCHSGWKGAECDV 625
Query: 467 ------DMSCPNDCHQHGRCVNGMCVCDDGYTGEDCRDRQC-PRDCSNRGLCVDGQCVCE 519
D++C N HG C+ G C+C+ GY GE C + C CS RG+CV G+C C
Sbjct: 626 PTNQCIDVACSN----HGTCITGTCICNPGYKGESCEEVDCMDPTCSGRGVCVRGECHCS 681
Query: 520 DGFTGPDCA--ELSCPNDCHGQGRCV--NGQCVCHEGFMGKDCKEQRCPSDCHGQGRCVD 575
G+ G +C +C + C G G + G C C + G DC + C +DC G G CV
Sbjct: 682 VGWGGTNCETPRATCLDQCSGHGTFLPDTGLCSCDPSWTGHDCSIEICAADCGGHGVCVG 741
Query: 576 GQCICHEGFTGLDCGQHSCPSDCNNLGQCVSGRCICNEGYSGEDCSEVSPPKDLVVTE 633
G C C +G+ G C Q +C C G C G+C C+ G++GE C+ ++ D VV E
Sbjct: 742 GTCRCEDGWMGAACDQRACHPRCAEHGTCRDGKCECSPGWNGEHCT-IAHYLDRVVKE 798
Score = 182 bits (461), Expect = 4e-45
Identities = 90/263 (34%), Positives = 122/263 (46%), Gaps = 22/263 (8%)
Query: 161 CSGRGNFSTEGCGCVCEPGWKGPNCSEPECPGNCHLRGRCIDGQCICDDGFTGEDC---S 217
C G G+ + C C G+ GP+C CP C G+ + G+C+C G+ G +C +
Sbjct: 570 CYGNGDCISGTCHCFL--GFLGPDCGRASCPVLCSGNGQYMKGRCLCHSGWKGAECDVPT 627
Query: 218 QLACPSDCNDQGKCVNGVCICFEGYAGADCSREICPVPCSEEHGTCVDGLCVCHDGFAGD 277
C++ G C+ G CIC GY G C C P G CV G C C G+ G
Sbjct: 628 NQCIDVACSNHGTCITGTCICNPGYKGESCEEVDCMDPTCSGRGVCVRGECHCSVGWGGT 687
Query: 278 DCNKP--LCLNNCYNRGRCVENE--CVCDEGFTGEDCSELICPNDCFDRGRCINGTCYCE 333
+C P CL+ C G + + C CD +TG DCS IC DC G C+ GTC CE
Sbjct: 688 NCETPRATCLDQCSGHGTFLPDTGLCSCDPSWTGHDCSIEICAADCGGHGVCVGGTCRCE 747
Query: 334 EGFTGEDCGKPTCPHACHTQGRCEEGQCVCDEGFAGVDCS---------EKRCPADCHNR 384
+G+ G C + C C G C +G+C C G+ G C+ ++ CP C+
Sbjct: 748 DGWMGAACDQRACHPRCAEHGTCRDGKCECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGN 807
Query: 385 GRCV----DGRCECDDGFTGADC 403
GRC C C G+ GA C
Sbjct: 808 GRCTLDLNGWHCVCQLGWRGAGC 830
Score = 169 bits (427), Expect = 4e-41
Identities = 101/305 (33%), Positives = 135/305 (44%), Gaps = 30/305 (9%)
Query: 119 VKELLSRLEELENLVSSL--REQCTAGAGCC----LQPATGRLDTRPFCSGRGNFSTEGC 172
V L + +E ++N S+ C +G C L P GR CSG G +
Sbjct: 553 VSFLTTAIESVDNCPSNCYGNGDCISGTCHCFLGFLGPDCGRASCPVLCSGNGQYMKG-- 610
Query: 173 GCVCEPGWKGPNCSEP--EC-PGNCHLRGRCIDGQCICDDGFTGEDCSQLAC-PSDCNDQ 228
C+C GWKG C P +C C G CI G CIC+ G+ GE C ++ C C+ +
Sbjct: 611 RCLCHSGWKGAECDVPTNQCIDVACSNHGTCITGTCICNPGYKGESCEEVDCMDPTCSGR 670
Query: 229 GKCVNGVCICFEGYAGADCS--REICPVPCSEEHGTCV--DGLCVCHDGFAGDDCNKPLC 284
G CV G C C G+ G +C R C CS HGT + GLC C + G DC+ +C
Sbjct: 671 GVCVRGECHCSVGWGGTNCETPRATCLDQCS-GHGTFLPDTGLCSCDPSWTGHDCSIEIC 729
Query: 285 LNNCYNRGRCVENECVCDEGFTGEDCSELICPNDCFDRGRCINGTCYCEEGFTGEDCG-- 342
+C G CV C C++G+ G C + C C + G C +G C C G+ GE C
Sbjct: 730 AADCGGHGVCVGGTCRCEDGWMGAACDQRACHPRCAEHGTCRDGKCECSPGWNGEHCTIA 789
Query: 343 -------KPTCPHACHTQGRC----EEGQCVCDEGFAGVDCSEKRCPADCHNRGRCVDGR 391
K CP C+ GRC CVC G+ G C A ++ DG
Sbjct: 790 HYLDRVVKEGCPGLCNGNGRCTLDLNGWHCVCQLGWRGAGCDTSMETACGDSKDNDGDGL 849
Query: 392 CECDD 396
+C D
Sbjct: 850 VDCMD 854
Score = 107 bits (268), Expect = 1e-22
Identities = 42/96 (43%), Positives = 58/96 (60%), Gaps = 3/96 (3%)
Query: 531 SCPNDCHGQGRCVNGQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLDCG 590
+CP++C+G G C++G C C GF+G DC CP C G G+ + G+C+CH G+ G +C
Sbjct: 565 NCPSNCYGNGDCISGTCHCFLGFLGPDCGRASCPVLCSGNGQYMKGRCLCHSGWKGAECD 624
Query: 591 ---QHSCPSDCNNLGQCVSGRCICNEGYSGEDCSEV 623
C+N G C++G CICN GY GE C EV
Sbjct: 625 VPTNQCIDVACSNHGTCITGTCICNPGYKGESCEEV 660
Score = 96.7 bits (239), Expect = 2e-19
Identities = 64/207 (30%), Positives = 86/207 (41%), Gaps = 37/207 (17%)
Query: 140 CTAGAGC--CLQPATGRLDTRPFCSGRGNFSTEGCGCVCEPGWKGPNCSEPECPGNCHLR 197
C+ G G C P LD CSG G F + C C+P W G +CS C +C
Sbjct: 680 CSVGWGGTNCETPRATCLDQ---CSGHGTFLPDTGLCSCDPSWTGHDCSIEICAADCGGH 736
Query: 198 GRCIDGQCICDDGFTGEDCSQLACPSDCNDQGKCVNGVCICFEGYAGADCS--------- 248
G C+ G C C+DG+ G C Q AC C + G C +G C C G+ G C+
Sbjct: 737 GVCVGGTCRCEDGWMGAACDQRACHPRCAEHGTCRDGKCECSPGWNGEHCTIAHYLDRVV 796
Query: 249 REICPVPCSEEHGTCVDGL----CVCHDGFAGDDCNKPLCLNNCYNRGRCVENECVCDEG 304
+E CP C+ +G C L CVC G+ G C+ + E C +
Sbjct: 797 KEGCPGLCN-GNGRCTLDLNGWHCVCQLGWRGAGCDTSM--------------ETACGDS 841
Query: 305 FTGEDCSELICPNDCFDRGRCINGTCY 331
D L+ DC D C+ C+
Sbjct: 842 -KDNDGDGLV---DCMDPDCCLQPLCH 864
Score = 42.0 bits (97), Expect = 0.007
Identities = 16/34 (47%), Positives = 20/34 (58%)
Query: 593 SCPSDCNNLGQCVSGRCICNEGYSGEDCSEVSPP 626
+CPS+C G C+SG C C G+ G DC S P
Sbjct: 565 NCPSNCYGNGDCISGTCHCFLGFLGPDCGRASCP 598
>gi|148833508 notch1 preproprotein [Homo sapiens]
Length = 2555
Score = 221 bits (563), Expect = 6e-57
Identities = 176/583 (30%), Positives = 240/583 (41%), Gaps = 112/583 (19%)
Query: 147 CLQPATGRLDTRPFCSGRGN---FSTEGCGCVCEPGWKGPNCSEPE-CPGN-CHLRGRCI 201
CL P T P C G + C C PGW G +C + + C N C G+C+
Sbjct: 98 CLTPLDNACLTNP-CRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCL 156
Query: 202 DGQ----CICDDGFTGEDCSQ--LAC---PSDCNDQGKCVNGV----CICFEGYAGADCS 248
+ C C F G C Q C P C G C N V C+C + G +C
Sbjct: 157 PFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCE 216
Query: 249 REICPVPCS----EEHGTC-----VDGLCVCHDGFAGDDCNKPL--CL-NNCYNRGRCVE 296
R VPCS + GTC V C C GF G +C + + C NNC N G CV+
Sbjct: 217 RPY--VPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVD 274
Query: 297 N----ECVCDEGFTGEDCSE-----LICPNDCFDRGRCING----TCYCEEGFTGEDCGK 343
C C +TG+ C+E + PN C + G C N C C G+TGEDC +
Sbjct: 275 GVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSE 334
Query: 344 -------PTCPHACHTQGRCEEGQCVCDEGFAGVDC--SEKRCPADCHNRGRC----VDG 390
C H R C C G G+ C ++ C+ C V+G
Sbjct: 335 NIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNG 394
Query: 391 R--CECDDGFTGADCGE--LKC---PNGCSGHGRCVNG----QCVCDEGYTG-------E 432
+ C C G+TG C + +C N C G+C+N +C C +GYTG
Sbjct: 395 KAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVN 454
Query: 433 DCSQLRCPNDCHSRGRCVEGKCVCEQGFKGYDC---SDMSCPNDCHQHGRCVNGM----C 485
+C C ND + E +C+C G++G C +D + C +GRC++ + C
Sbjct: 455 ECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQC 514
Query: 486 VCDDGYTGEDCR---DRQCPRDCSNRGLCVDG----QCVCEDGFTGPDC---AELSCPND 535
C G+TG C+ D C N C+DG CVC +G+TG C + P+
Sbjct: 515 ECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDP 574
Query: 536 CHGQGRCVNG----QCVCHEGFMGKDCKE--QRCPSD-CHGQGRCVDGQ----CICHEGF 584
CH G C +G C+C G+ G C+ C S C G C D C C +G
Sbjct: 575 CH-YGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGT 633
Query: 585 TGLDC--GQHSCPSDCNNLGQCVSG----RCICNEGYSGEDCS 621
TG +C C S + G C+ C C GY+G C+
Sbjct: 634 TGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCN 676
Score = 221 bits (562), Expect = 8e-57
Identities = 187/611 (30%), Positives = 250/611 (40%), Gaps = 156/611 (25%)
Query: 161 CSGRGNFSTEGCGCVCEPGWKGPNCSE--PECPGN-CHLRGRCIDG----QCICDDGFTG 213
C G+ + E C C PG+ G NC E +CPGN C G C+DG C C +TG
Sbjct: 233 CRPTGDVTHE---CACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTG 289
Query: 214 EDCSQ-----LACPSDCNDQGKCVNGV----CICFEGYAGADCSREI--CPVPCSEEHGT 262
+ C++ P+ C + G C N C+C G+ G DCS I C T
Sbjct: 290 QYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGAT 349
Query: 263 CVDGL----CVCHDGFAGDDCN-KPLCLNNCYNRG-RCVENE------CVCDEGFTGEDC 310
C D + C C G G C+ C++N N G C N C C G+TG C
Sbjct: 350 CHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPAC 409
Query: 311 SELI--CP---NDCFDRGRCINGT----CYCEEGFTGEDCG---KPTCPHACHTQGRC-- 356
S+ + C N C G+CIN C C +G+TG C + C C
Sbjct: 410 SQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLD 469
Query: 357 --EEGQCVCDEGFAGVDC---SEKRCPADCHNRGRCVDG----RCECDDGFTGA------ 401
E QC+C G+ GV C +++ + C + GRC+D +CEC GFTG
Sbjct: 470 QIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDV 529
Query: 402 -DCGELKCPNGCSGHGRCVNGQ----CVCDEGYTGEDCSQL--RC-PNDCHSRGRCVEG- 452
+C C NG +C++G CVC EGYTG C C P+ CH G C +G
Sbjct: 530 DECASTPCKNGA----KCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHY-GSCKDGV 584
Query: 453 ---KCVCEQGFKGY-------DCSDMSC-----------------------PN------D 473
C+C G+ G+ +CS C PN D
Sbjct: 585 ATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDD 644
Query: 474 CHQH----GRCVNGM----CVCDDGYTGEDCR---DRQCPRDCSNRGLCVDG----QCVC 518
C G C++ + C C+ GYTG C D C N G C DG C C
Sbjct: 645 CASSPCDSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRC 704
Query: 519 EDGFTGPDCAELSCPNDCHGQGRCVNG---------QCVCHEGFMGKDC--KEQRCPSD- 566
+G+ P C LS N+C+ CV+G +C C G+ G +C C S+
Sbjct: 705 PEGYHDPTC--LSEVNECNSNP-CVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNP 761
Query: 567 CHGQGRCVDGQ----CICHEGFTGLDCGQH--SCPSD-CNNLGQCVSG----RCICNEGY 615
C G C D C C EGF+G +C + C S+ C N G C+ +C C Y
Sbjct: 762 CVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPY 821
Query: 616 SGEDCSEVSPP 626
+G C V P
Sbjct: 822 TGATCEVVLAP 832
Score = 214 bits (545), Expect = 7e-55
Identities = 173/592 (29%), Positives = 239/592 (40%), Gaps = 147/592 (24%)
Query: 171 GCGCVCEPGWKGPNCSEP------------------------ECPGN-----CHLRGRCI 201
G CVC GW G +CSE ECP CHL CI
Sbjct: 318 GYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACI 377
Query: 202 DGQ-----------------CICDDGFTGEDCSQ-----LACPSDCNDQGKCVNGV---- 235
C C G+TG CSQ + C GKC+N +
Sbjct: 378 SNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFE 437
Query: 236 CICFEGYAGADCS---REICPVPCSEEHGTCVDGL----CVCHDGFAGDDC--NKPLCLN 286
C C +GY G C E PC + TC+D + C+C G+ G C N C +
Sbjct: 438 CQCLQGYTGPRCEIDVNECVSNPCQND-ATCLDQIGEFQCICMPGYEGVHCEVNTDECAS 496
Query: 287 N-CYNRGRCV----ENECVCDEGFTGEDCS---ELICPNDCFDRGRCING----TCYCEE 334
+ C + GRC+ E +C C GFTG C + C + +C++G TC C E
Sbjct: 497 SPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTE 556
Query: 335 GFTGEDCG---KPTCPHACHTQGRCEEG----QCVCDEGFAGVDCSE--KRCPAD-CHNR 384
G+TG C P CH G C++G C+C G+ G C C + C +
Sbjct: 557 GYTGTHCEVDIDECDPDPCH-YGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHG 615
Query: 385 GRCVDG----RCECDDGFTGADCGELK---CPNGCSGHGRCVNG----QCVCDEGYTGED 433
G C D C C G TG +C E+ C + G C++ +C C+ GYTG
Sbjct: 616 GTCQDRDNAYLCFCLKGTTGPNC-EINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSM 674
Query: 434 CS---QLRCPNDCHSRGRCVEG----KCVCEQGFKGYDCSDMSCPNDCHQ----HGRC-- 480
C+ N CH+ G C +G C C +G+ +D + +S N+C+ HG C
Sbjct: 675 CNINIDECAGNPCHNGGTCEDGINGFTCRCPEGY--HDPTCLSEVNECNSNPCVHGACRD 732
Query: 481 -VNG-MCVCDDGYTGEDC--RDRQCPRD-CSNRGLCVDGQ----CVCEDGFTGPDC---A 528
+NG C CD G++G +C + +C + C N G C D C C +GF+GP+C
Sbjct: 733 SLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNI 792
Query: 529 ELSCPNDCHGQGRCVNG----QCVCHEGFMGKDCK---EQRCPSDCHGQGRCVDGQ---- 577
N C QG C++ +C C + G C+ PS C G C +
Sbjct: 793 NECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYES 852
Query: 578 --CICHEGFTGLDCG---QHSCPSDCNNLGQCVSG----RCICNEGYSGEDC 620
C+C G+ G C S C + C + RC C GYSG +C
Sbjct: 853 FSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNC 904
Score = 206 bits (524), Expect = 2e-52
Identities = 165/548 (30%), Positives = 216/548 (39%), Gaps = 112/548 (20%)
Query: 181 KGPNCSEPECPGNCHLRGRCIDGQ----CICDDGFTGEDCSQ----LACPSDCNDQGKC- 231
+GP CS+P C G+C C+C F G C L+ P C + G C
Sbjct: 20 RGPRCSQPG--ETCLNGGKCEAANGTEACVCGGAFVGPRCQDPNPCLSTP--CKNAGTCH 75
Query: 232 -------VNGVCICFEGYAGADCSREI---CPVPCSEEHGTC-----VDGLCVCHDGFAG 276
+ C C G++G C + C GTC + C C G++G
Sbjct: 76 VVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSG 135
Query: 277 DDCNK--PLCLNNCYNRGRCVENE----CVCDEGFTGEDCSELI--C---PNDCFDRGRC 325
C + P N C N G+C+ E C C F G C + + C P C G C
Sbjct: 136 KSCQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTC 195
Query: 326 INGT----CYCEEGFTGEDCGKP---TCPHACHTQGRCEEG-----QCVCDEGFAGVDCS 373
N C C TG +C +P P C G C +C C GF G +C
Sbjct: 196 HNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCE 255
Query: 374 EK--RCPAD-CHNRGRCVDG----RCECDDGFTGADCGEL--KC---PNGCSGHGRCVNG 421
E CP + C N G CVDG C C +TG C E +C PN C G C N
Sbjct: 256 ENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNT 315
Query: 422 Q----CVCDEGYTGEDCSQ-------LRCPNDCHSRGRCVEGKCVCEQGFKGYDC--SDM 468
CVC G+TGEDCS+ C + R C C G G C +D
Sbjct: 316 HGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDA 375
Query: 469 SCPNDCHQHGRC----VNG--MCVCDDGYTGEDCRD--RQC---PRDCSNRGLCVDG--- 514
N C++ C VNG +C C GYTG C +C C + G C++
Sbjct: 376 CISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGS 435
Query: 515 -QCVCEDGFTGP-------DCAELSCPNDCHGQGRCVNGQCVCHEGFMGKDCK---EQRC 563
+C C G+TGP +C C ND + QC+C G+ G C+ ++
Sbjct: 436 FECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECA 495
Query: 564 PSDCHGQGRCVDG----QCICHEGFTGLDCG---QHSCPSDCNNLGQCVSG----RCICN 612
S C GRC+D QC C GFTG C + C N +C+ G C+C
Sbjct: 496 SSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCT 555
Query: 613 EGYSGEDC 620
EGY+G C
Sbjct: 556 EGYTGTHC 563
Score = 206 bits (524), Expect = 2e-52
Identities = 175/592 (29%), Positives = 229/592 (38%), Gaps = 129/592 (21%)
Query: 156 DTRPFCSGRGNFSTEGCGCVCEPGWKGPNC--SEPECPGN-CHLRGRCIDGQ----CICD 208
++ P G S G C C+PGW G NC + EC N C G C D C C
Sbjct: 721 NSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCR 780
Query: 209 DGFTGEDCSQLA--CPSD-CNDQGKCVNGV----CICFEGYAGADCSREICPV---PCSE 258
+GF+G +C C S+ C +QG C++ V C C Y GA C + P PC
Sbjct: 781 EGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPC-R 839
Query: 259 EHGTCVDG------LCVCHDGFAGDDCNKPL---CLNNCYNRGRCVENE----CVCDEGF 305
G C CVC G+ G C + L+ C + C C C G+
Sbjct: 840 NGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGY 899
Query: 306 TGEDCSELI--C-PNDCFDRGRCINGT----CYCEEGFTG-------EDCGKPTCPHACH 351
+G +C I C PN C + G C +G C C GF G +C C + +
Sbjct: 900 SGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGAN 959
Query: 352 TQGRCEEGQCVCDEGFAGVDCSEKRCP----ADCHNRGRCVDG----RCECDDGFTGA-- 401
+ C C GF+G+ C E P + C N G CVDG C C GFTG+
Sbjct: 960 CTDCVDSYTCTCPAGFSGIHC-ENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYC 1018
Query: 402 -----DCGELKCPNGCSGHGRCVNGQCVCDEGYTGEDCSQL--RCPND-CHSRGRC---- 449
+C C +G + C + +C C +GYTG +C L C + C + G+C
Sbjct: 1019 QHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTH 1078
Query: 450 VEGKCVCEQGFKGYDCS--DMSC-----------PNDCHQHGRCVNG----MCVCDDGYT 492
+ +C C G+ G C +SC C G CV+ C C GYT
Sbjct: 1079 TQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYT 1138
Query: 493 GEDCRD--RQC-PRDCSNRGLCVD----GQCVCEDGFTGPDCAE-----LSCPNDCHGQG 540
G C D +C P C N C D C C G+ G +C+E LS P C G
Sbjct: 1139 GSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHP--CQNGG 1196
Query: 541 RCVN----GQCVCHEGFMGKDCK------------EQRCPSDCHGQGRCVDG----QCIC 580
C++ +C C G G C+ R P C G CVD C C
Sbjct: 1197 TCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPK-CFNNGTCVDQVGGYSCTC 1255
Query: 581 HEGFTGLDCGQH-----SCPSDCNNLGQCVSG----RCICNEGYSGEDCSEV 623
GF G C S P D CV C C G++G C V
Sbjct: 1256 PPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESV 1307
Score = 204 bits (518), Expect = 1e-51
Identities = 173/600 (28%), Positives = 240/600 (40%), Gaps = 160/600 (26%)
Query: 174 CVCEPGWKGPNCSEP--------ECPGNCHLRGR-------------------------- 199
CVC + GP C +P + G CH+ R
Sbjct: 46 CVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNA 105
Query: 200 -----CIDG-----------QCICDDGFTGEDCSQL-ACPSD-CNDQGKCV----NGVCI 237
C +G +C C G++G+ C Q C S+ C + G+C+ + +C
Sbjct: 106 CLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFEASYICH 165
Query: 238 CFEGYAGADCSREICPVPCSEEHGTCVDG----------LCVCHDGFAGDDCNK---PLC 284
C + G C +++ C ++ G C G CVC G +C + P
Sbjct: 166 CPPSFHGPTCRQDV--NECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCS 223
Query: 285 LNNCYNRGRC-----VENECVCDEGFTGEDCSELI--CP-NDCFDRGRCING----TCYC 332
+ C N G C V +EC C GFTG++C E I CP N+C + G C++G C C
Sbjct: 224 PSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRC 283
Query: 333 EEGFTGEDCGKPT-----CPHACHTQGRCEEG----QCVCDEGFAGVDCSEK---RCPAD 380
+TG+ C + P+AC G C CVC G+ G DCSE A
Sbjct: 284 PPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAA 343
Query: 381 CHNRGRCVDG----RCECDDGFTGADC--GELKCPNGCSGHGRC----VNGQ--CVCDEG 428
C + C D CEC G TG C + N C+ C VNG+ C C G
Sbjct: 344 CFHGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSG 403
Query: 429 YTGEDCSQ--LRC---PNDCHSRGRCVEG----KCVCEQGFKGYDCS---DMSCPNDCHQ 476
YTG CSQ C N C G+C+ +C C QG+ G C + N C
Sbjct: 404 YTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQN 463
Query: 477 HGRCVNGM----CVCDDGYTGEDCR---DRQCPRDCSNRGLCVDG----QCVCEDGFTG- 524
C++ + C+C GY G C D C + G C+D QC C GFTG
Sbjct: 464 DATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGH 523
Query: 525 ------PDCAELSCPNDCHGQGRCVNG----QCVCHEGFMGKDCK---EQRCPSDCHGQG 571
+CA C N +C++G CVC EG+ G C+ ++ P CH G
Sbjct: 524 LCQYDVDECASTPCKNG----AKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCH-YG 578
Query: 572 RCVDG----QCICHEGFTGLDC--GQHSCPSD-CNNLGQCV----SGRCICNEGYSGEDC 620
C DG C+C G+TG C + C S C + G C + C C +G +G +C
Sbjct: 579 SCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNC 638
Score = 201 bits (512), Expect = 5e-51
Identities = 174/629 (27%), Positives = 241/629 (38%), Gaps = 167/629 (26%)
Query: 140 CTAGAGCCLQPATGRLDTRPFCSGRGNFSTEGCGCVCEPGWKGPNCSEP--ECP---GNC 194
C G+ C P G+ C C G+ GP CS+ EC C
Sbjct: 381 CNEGSNCDTNPVNGKAI-----------------CTCPSGYTGPACSQDVDECSLGANPC 423
Query: 195 HLRGRCIDG----QCICDDGFTGEDCS---QLACPSDCNDQGKCVNGV----CICFEGYA 243
G+CI+ +C C G+TG C + C + C++ + CIC GY
Sbjct: 424 EHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYE 483
Query: 244 GADC---SREICPVPCSEEHGTCVDGL----CVCHDGFAGDDCNKPL--CLNN-CYNRGR 293
G C + E PC +G C+D + C C GF G C + C + C N +
Sbjct: 484 GVHCEVNTDECASSPCLH-NGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAK 542
Query: 294 CVENE----CVCDEGFTGEDCSELI--CPNDCFDRGRCING----TCYCEEGFTGE---- 339
C++ CVC EG+TG C I C D G C +G TC C G+TG
Sbjct: 543 CLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHCET 602
Query: 340 ---DCGKPTCPHACHTQGRCEEGQCVCDEGFAGVDCSEKR--CPADCHNRGRCVDG---- 390
+C C H Q R C C +G G +C C + + G C+D
Sbjct: 603 NINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGY 662
Query: 391 RCECDDGFTGADCG---ELKCPNGCSGHGRCVNG----QCVCDEGYTGEDCSQLRCPNDC 443
C C+ G+TG+ C + N C G C +G C C EGY C L N+C
Sbjct: 663 ECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTC--LSEVNEC 720
Query: 444 HSRGRCVEG---------KCVCEQGFKGYDCSDMSCPNDCHQHGRCVNG----------M 484
+S CV G KC C+ G+ G +C + N+C + CVNG +
Sbjct: 721 NSNP-CVHGACRDSLNGYKCDCDPGWSGTNCDINN--NECESNP-CVNGGTCKDMTSGYV 776
Query: 485 CVCDDGYTGEDCRDR--QCPRD-CSNRGLCVDG----QCVCEDGFTGPDCAEL---SCPN 534
C C +G++G +C+ +C + C N+G C+D +C C +TG C + P+
Sbjct: 777 CTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPS 836
Query: 535 DCHGQGRCVNGQ------CVCHEGFMGKDCKEQ----------------------RC--- 563
C G C + CVC G+ G+ C+ RC
Sbjct: 837 PCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQ 896
Query: 564 ----------------PSDCHGQGRCVDGQ----CICHEGFTGLDCGQ--HSCPSD-CNN 600
P+ CH G C DG C C GF G C + + C SD C N
Sbjct: 897 AGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRN 956
Query: 601 LGQCV----SGRCICNEGYSGEDCSEVSP 625
C S C C G+SG C +P
Sbjct: 957 GANCTDCVDSYTCTCPAGFSGIHCENNTP 985
Score = 164 bits (415), Expect = 9e-40
Identities = 166/602 (27%), Positives = 215/602 (35%), Gaps = 162/602 (26%)
Query: 171 GCGCVCEPGWKGPNCSEP--EC-PGNCHLRGRCIDGQ----CICDDGFTGEDCSQ--LAC 221
G C C+ G+ G NC +C P CH G C DG C C GF G C + C
Sbjct: 890 GYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINEC 949
Query: 222 PSD-CNDQGKCVNGV----CICFEGYAGADCSREI--CPVPCSEEHGTCVDGL----CVC 270
SD C + C + V C C G++G C C GTCVDG+ C+C
Sbjct: 950 ASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLC 1009
Query: 271 HDGFAG-------DDCNKPLCLNNCYNRGRCVENECVCDEGFTGEDCSELI--CPND-CF 320
GF G ++C+ CL+ + C C C +G+TG +C L+ C + C
Sbjct: 1010 PPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCK 1069
Query: 321 DRGRC----INGTCYCEEGFTGEDCGKPT--CPHACHTQG-----RCEEG---------- 359
+ G+C C C G+TG C P+ C A QG C+ G
Sbjct: 1070 NGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTH 1129
Query: 360 QCVCDEGFAGVDCSE---KRCPADCHNRGRCVDG----RCECDDGFTGADCGE------- 405
C C G+ G C + + P+ C N C D C+C G+ G +C E
Sbjct: 1130 HCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLS 1189
Query: 406 -----------------LKCPNG-------------------------CSGHGRCVNG-- 421
CP G C +G CV+
Sbjct: 1190 HPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVG 1249
Query: 422 --QCVCDEGYTGEDCSQ--LRC-PNDCHSRG--RCVEG----KCVCEQGFKGYDCSDM-- 468
C C G+ GE C C N C +RG CV+ C C G G C +
Sbjct: 1250 GYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVIN 1309
Query: 469 SCPND-CHQHGRCVNG-------MCVCDDGYTGEDCRD--RQCPR-DCSNRGLCVDGQ-- 515
C C G C +C C G+ G C + R C C N G C+ G
Sbjct: 1310 GCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRS 1369
Query: 516 --CVCEDGFTGPDC---AELSC--PNDCHGQGRCVNG------QCVCHEGFMGKDCKEQR 562
C+C FTGP+C A C N C+ QG C +C+C F G C
Sbjct: 1370 PTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILD 1429
Query: 563 CPSDCHGQGRCVDGQCI---CHEGFTGLDCGQHSCPSDCNNLGQCVSGRCICNEGYSGED 619
S G GR + I C D G C CNN C G+ G D
Sbjct: 1430 Y-SFGGGAGRDIPPPLIEEACELPECQEDAGNKVCSLQCNN-HAC---------GWDGGD 1478
Query: 620 CS 621
CS
Sbjct: 1479 CS 1480
Score = 138 bits (347), Expect = 7e-32
Identities = 155/579 (26%), Positives = 218/579 (37%), Gaps = 135/579 (23%)
Query: 133 VSSLREQCTAG-AGCCLQPATGRLDTRPFCSGRGNFSTEGCG---CVCEPGWKGPNCSEP 188
++S C G G Q D++P G +GCG C C G+ GPNC
Sbjct: 1002 INSFTCLCPPGFTGSYCQHDVNECDSQPCL--HGGTCQDGCGSYRCTCPQGYTGPNCQNL 1059
Query: 189 E--CPGN-CHLRGRC----IDGQCICDDGFTGEDCSQLACPSD-------------CNDQ 228
C + C G+C +C C G+TG C + + C
Sbjct: 1060 VHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHG 1119
Query: 229 GKCVNGV----CICFEGYAGADCSR---EICPVPCSEEHGTCVDGL----CVCHDGFAGD 277
G CV+ C C GY G+ C E P PC + TC D L C C G+ G
Sbjct: 1120 GLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPC-QNGATCTDYLGGYSCKCVAGYHGV 1178
Query: 278 DCNKPL--CLNN-CYNRGRCVE----NECVCDEGFTG-------EDCSELICPND----C 319
+C++ + CL++ C N G C++ +C C G G +DC+ + P C
Sbjct: 1179 NCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKC 1238
Query: 320 FDRGRCING----TCYCEEGFTGEDCG---KPTCPHACHTQG------RCEEGQCVCDEG 366
F+ G C++ +C C GF GE C + C +G R + C C G
Sbjct: 1239 FNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAG 1298
Query: 367 FAGVDCSE--KRCPAD-CHNRGRCVDGR-------CECDDGFTGADC-------GELKCP 409
G C C C N G C C+C GF GA C G L+C
Sbjct: 1299 HTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCL 1358
Query: 410 NGCSGHGRCVNGQ----CVCDEGYTGEDC-----SQLRCPNDCHSRGRCVEG------KC 454
NG G C++G C+C +TG +C S N C+++G C +C
Sbjct: 1359 NG----GTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRC 1414
Query: 455 VCEQGFKGYDCS--DMSCPNDCHQHGRCVNGMCV---CDDGYTGEDCRDRQCPRDCSNRG 509
+C F G C D S GR + + C+ ED ++ C C+N
Sbjct: 1415 LCPAKFNGLLCHILDYSFGGGA---GRDIPPPLIEEACELPECQEDAGNKVCSLQCNNHA 1471
Query: 510 LCVDGQCVCEDGFTGP--DCAE-LSCP---NDCHGQGRCVNGQCVCHEGFMGKDCK---- 559
DG C F P +C + L C +D H +C + C+ F G DC+
Sbjct: 1472 CGWDGGD-CSLNFNDPWKNCTQSLQCWKYFSDGHCDSQCNSAGCL----FDGFDCQRAEG 1526
Query: 560 ------EQRCPSDCHGQGRCVDGQCICHEGFTGLDCGQH 592
+Q C D G C G + GLDC +H
Sbjct: 1527 QCNPLYDQYC-KDHFSDGHCDQGCNSAECEWDGLDCAEH 1564
Score = 118 bits (296), Expect = 6e-26
Identities = 101/345 (29%), Positives = 132/345 (38%), Gaps = 91/345 (26%)
Query: 338 GEDCGKPTCPHACHTQGRCEEGQ----CVCDEGFAGVDCSEKR--CPADCHNRGRC---- 387
G C +P C G+CE CVC F G C + C N G C
Sbjct: 21 GPRCSQPG--ETCLNGGKCEAANGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVD 78
Query: 388 ----VDGRCECDDGFTGADCGELKCPNGCSGHGRCVNGQCVCDEGYTGEDCSQLRCPNDC 443
D C C GF+G C N C N C
Sbjct: 79 RRGVADYACSCALGFSGPLC-LTPLDNAC--------------------------LTNPC 111
Query: 444 HSRGRC-----VEGKCVCEQGFKGYDC--SDMSCPNDCHQHGRCV----NGMCVCDDGYT 492
+ G C E KC C G+ G C +D N C G+C+ + +C C +
Sbjct: 112 RNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSFH 171
Query: 493 GEDCRDRQCPRDCSNR-GLCVDG----------QCVCEDGFTGPDCAE--LSC-PNDCHG 538
G CR Q +C + GLC G +CVC TGP+C + C P+ C
Sbjct: 172 GPTCR--QDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQN 229
Query: 539 QGRC-----VNGQCVCHEGFMGKDCKEQ--RCP-SDCHGQGRCVDG----QCICHEGFTG 586
G C V +C C GF G++C+E CP ++C G CVDG C C +TG
Sbjct: 230 GGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTG 289
Query: 587 LDCGQH--SC---PSDCNNLGQCVSGR----CICNEGYSGEDCSE 622
C + C P+ C N G C + C+C G++GEDCSE
Sbjct: 290 QYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSE 334
Score = 68.2 bits (165), Expect = 9e-11
Identities = 57/191 (29%), Positives = 77/191 (40%), Gaps = 38/191 (19%)
Query: 474 CHQHGRC--VNGM--CVCDDGYTGEDCRDRQ--CPRDCSNRGLC--------VDGQCVCE 519
C G+C NG CVC + G C+D C N G C D C C
Sbjct: 31 CLNGGKCEAANGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYACSCA 90
Query: 520 DGFTGPDCA---ELSC-PNDCHGQGRC-----VNGQCVCHEGFMGKDCKE-QRCPSD-CH 568
GF+GP C + +C N C G C +C C G+ GK C++ C S+ C
Sbjct: 91 LGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCA 150
Query: 569 GQGRCVDGQ----CICHEGFTGLDCGQ--HSC---PSDCNNLGQCV----SGRCICNEGY 615
G+C+ + C C F G C Q + C P C + G C S RC+C +
Sbjct: 151 NGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATH 210
Query: 616 SGEDCSEVSPP 626
+G +C P
Sbjct: 211 TGPNCERPYVP 221
Score = 46.6 bits (109), Expect = 3e-04
Identities = 36/125 (28%), Positives = 52/125 (41%), Gaps = 25/125 (20%)
Query: 524 GPDCAELSCPNDCHGQGRC--VNGQ--CVCHEGFMGKDCKEQR--CPSDCHGQGRC---- 573
GP C++ C G+C NG CVC F+G C++ + C G C
Sbjct: 21 GPRCSQPG--ETCLNGGKCEAANGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVD 78
Query: 574 ----VDGQCICHEGFTGLDCG---QHSCPSD-CNNLGQC-----VSGRCICNEGYSGEDC 620
D C C GF+G C ++C ++ C N G C +C C G+SG+ C
Sbjct: 79 RRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSC 138
Query: 621 SEVSP 625
+ P
Sbjct: 139 QQADP 143
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 219 bits (557), Expect = 3e-56
Identities = 188/639 (29%), Positives = 245/639 (38%), Gaps = 198/639 (30%)
Query: 173 GCVCEPGWKGPNCSEPECPG-----------NCHLRGRC--IDGQCICDDGFTGEDCSQL 219
GC C GW G C+E CP +C G C + G C C G +G +C
Sbjct: 539 GCDCPEGWTGLICNE-TCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSGTNCED- 596
Query: 220 ACPS-----------DCNDQGKC--VNGVCICFEGYAGADCSREICPV----PCSEEHGT 262
CP +C ++G+C + G C+C G G C CP P E
Sbjct: 597 GCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFC-HLTCPPWAFGPGCSEECQ 655
Query: 263 CV----------DGLCVCHDGFAGDDCNKPLCLN----NCYNRGRC--------VENEC- 299
CV DG C C GF G+ C L C+ C V EC
Sbjct: 656 CVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVSGECG 715
Query: 300 -VCDEGFTGEDCSE--------LICPNDCFDRG---RCINGTCYCEEGFTGEDCGKPTCP 347
C GF GEDC + + C + C G + G C C G TGEDC + CP
Sbjct: 716 KRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDC-EADCP 774
Query: 348 H------------ACHTQGRC--EEGQCVCDEGFAGVDCSEKRCPA-----------DCH 382
AC RC E G C+C GF G C + CPA C
Sbjct: 775 EGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDV-CPAGWYGPSCQTRCSCA 833
Query: 383 NRGRC--VDGRCECDDGFTGADCGEL--------KCPNGC---SGHGRC--VNGQCVCDE 427
N G C G C C G+TG C C + C +GHG C ++G C+C+
Sbjct: 834 NDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEA 893
Query: 428 GYTGEDCSQLRCPN-----DCHSRGRC--------VEGKCVCEQGFKGYDCSDMSCPN-- 472
GY G C Q +CP C R +C V G C C G++G C + +CP
Sbjct: 894 GYVGPRCEQ-QCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFC-EHACPAGF 951
Query: 473 ---DCHQHGRC--------VNGMCVCDDGYTGEDCRDRQCP-----RDCSNRGLC----- 511
DC C VNG C+C G G C + CP +CS C
Sbjct: 952 FGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAE-TCPAHTYGHNCSQACACFNGAS 1010
Query: 512 ---VDGQCVCEDGFTGPDCAELSCPND-----------CHGQGRC--VNGQCVCHEGFMG 555
V GQC C G+ GP C + +CP C G C V+G C C EG+ G
Sbjct: 1011 CDPVHGQCHCAPGWMGPSCLQ-ACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAG 1069
Query: 556 KDCKEQRCPSD----CHGQGRCVD--------GQCICHEGFTGLDC-------------- 589
C+++ P D C G C++ G+C+C G+TG C
Sbjct: 1070 LACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACA 1129
Query: 590 GQHSCP--SDCNNLGQCVSGRCICNEGYSGEDCSEVSPP 626
+ SCP + C++ V+G C C G++G C + PP
Sbjct: 1130 QRCSCPPGAACHH----VTGACRCPPGFTGSGCEQACPP 1164
Score = 219 bits (557), Expect = 3e-56
Identities = 199/658 (30%), Positives = 247/658 (37%), Gaps = 186/658 (28%)
Query: 143 GAGC-----CLQPATGRLDTRP-FCSGRGNFSTEGCGCVCEPGWKGPNCSEPECPGNCHL 196
G GC C+QP T D R CS + F E C CE G+ GP C + C +
Sbjct: 647 GPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQ-ACTCPVGV 705
Query: 197 RGRCIDGQC--ICDDGFTGEDCSQ--------LACPSDCNDQGKCVNGV---CICFEGYA 243
+ G+C C GF GEDC Q + C S C+ G +GV C C G
Sbjct: 706 ACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRT 765
Query: 244 GADCS------------REICPVPCSEEHGTCVD---GLCVCHDGFAGDDCNK------- 281
G DC +EICP C +H D G C+C GF G C
Sbjct: 766 GEDCEADCPEGRWGLGCQEICPA-C--QHAARCDPETGACLCLPGFVGSRCQDVCPAGWY 822
Query: 282 -PLCLN--NCYNRGRC--VENECVCDEGFTGEDCSELI--------CPNDC---FDRGRC 325
P C +C N G C C C G+TG C C + C G C
Sbjct: 823 GPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSC 882
Query: 326 --INGTCYCEEGFTGEDCGK--------PTCPHACHTQ--GRCE--EGQCVCDEGFAGVD 371
I+G C CE G+ G C + P C C Q C+ G C C G+ G
Sbjct: 883 DAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTF 942
Query: 372 CSEKRCPA-----DCHNRGRC--------VDGRCECDDGFTGADCGELKCPNGCSGHG-- 416
C E CPA DC + C V+G C C G G C E CP GH
Sbjct: 943 C-EHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAE-TCPAHTYGHNCS 1000
Query: 417 -RC----------VNGQCVCDEGYTGEDCSQLRCPND-----------CHSRGRC--VEG 452
C V+GQC C G+ G C Q CP C + G C V G
Sbjct: 1001 QACACFNGASCDPVHGQCHCAPGWMGPSCLQ-ACPAGLYGDNCRHSCLCQNGGTCDPVSG 1059
Query: 453 KCVCEQGFKGYDCSDMSCPND----CHQHGRCVN--------GMCVCDDGYTGEDCRDRQ 500
C C +G+ G C P D C G C+N G C+C G+TG+ C+
Sbjct: 1060 HCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQS-P 1118
Query: 501 CPRD-----CSNRGLC--------VDGQCVCEDGFTGPDCAELSCP-----NDCHGQGRC 542
C R C+ R C V G C C GFTG C E +CP DC +C
Sbjct: 1119 CLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGC-EQACPPGSFGEDCAQMCQC 1177
Query: 543 ---------VNGQCVCHEGFMGKDCKEQRCPSDCHGQG-----RCVD--------GQCIC 580
G C C G+ G C +QRCP +G G C++ G C C
Sbjct: 1178 PGENPACHPATGTCSCAAGYHGPSC-QQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRC 1236
Query: 581 HEGFTGLDCGQHSCPS-----DCNNLGQC--------VSGRCICNEGYSGEDCSEVSP 625
GF G DC +CP +C ++ C V+G C+C G +G C P
Sbjct: 1237 PTGFLGTDCNL-TCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCP 1293
Score = 216 bits (549), Expect = 3e-55
Identities = 196/692 (28%), Positives = 251/692 (36%), Gaps = 229/692 (33%)
Query: 140 CTAGAGCCLQPATGRLDTRPFCSGRGNFSTEGCGCVCEPGWKGPNCSEPECPGNCHLRGR 199
C A C P TG C F C VC GW GP+C + C +C G
Sbjct: 789 CQHAARC--DPETGA------CLCLPGFVGSRCQDVCPAGWYGPSC-QTRC--SCANDGH 837
Query: 200 C--IDGQCICDDGFTGEDCSQLA--------CPSDCN---DQGKC--VNGVCICFEGYAG 244
C G C C G+TG C + C CN G C ++G+C+C GY G
Sbjct: 838 CHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVG 897
Query: 245 ADCSREI--------CPVPCSEEHGTCVD---GLCVCHDGFAGDDCN------------K 281
C ++ C C +HG D G C C G+ G C +
Sbjct: 898 PRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCR 957
Query: 282 PLCLNNCYNRGRC--VENECVCDEGFTGEDCSELICPND-----------CFDRGRC--I 326
C NC C V C+C G G C+E CP CF+ C +
Sbjct: 958 SAC--NCTAGAACDAVNGSCLCPAGRRGPRCAE-TCPAHTYGHNCSQACACFNGASCDPV 1014
Query: 327 NGTCYCEEGFTGEDCGK--------PTCPHACHTQ--GRCE--EGQCVCDEGFAGVDCSE 374
+G C+C G+ G C + C H+C Q G C+ G C C EG+AG+ C +
Sbjct: 1015 HGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEK 1074
Query: 375 KRCPAD----CHNRGRCVD--------GRCECDDGFTGADC------------------- 403
+ P D C + G C++ GRC C G+TG C
Sbjct: 1075 ECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSC 1134
Query: 404 ----------GELKCPNGCSGHG------------------RC---------VNGQCVCD 426
G +CP G +G G +C G C C
Sbjct: 1135 PPGAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCA 1194
Query: 427 EGYTGEDCSQLRCPN-----------DCHSRGRC--VEGKCVCEQGFKGYDCSDMSCPN- 472
GY G C Q RCP C + G C G C C GF G DC +++CP
Sbjct: 1195 AGYHGPSCQQ-RCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDC-NLTCPQG 1252
Query: 473 ----------DCHQHGRC--VNGMCVCDDGYTGEDCRDRQCPRD-----------CSNRG 509
C Q C V G C+C G G C +R CP++ C N G
Sbjct: 1253 RFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRC-ERGCPQNRFGVGCEHTCSCRNGG 1311
Query: 510 LC--VDGQCVCEDGFTGPDCAELSCPN-----------DCHGQGRC--VNGQCVCHEGFM 554
LC +G C C G+TG C EL+CP CH C G C C GF
Sbjct: 1312 LCHASNGSCSCGLGWTGRHC-ELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFY 1370
Query: 555 GKDCKEQRCPSDCHG---QGRC----------VDGQCICHEGFTGLDCGQHSCPS----- 596
G+ C E CP HG QG C + G+C+C GF G C + P
Sbjct: 1371 GQAC-EHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGCEPGSFGEG 1429
Query: 597 -----DCNNLGQC--VSGRCICNEGYSGEDCS 621
DC+ C V+G C+C G SG C+
Sbjct: 1430 CHQRCDCDGGAPCDPVTGLCLCPPGRSGATCN 1461
Score = 213 bits (541), Expect = 2e-54
Identities = 199/650 (30%), Positives = 239/650 (36%), Gaps = 204/650 (31%)
Query: 162 SGRGNFSTEGCGCVCEPGWKGPNCSEPECPGN-----CHLRGRC--------IDGQCICD 208
+G G+ C+CE G+ GP C E +CP C R +C + G C C
Sbjct: 877 AGHGSCDAISGLCLCEAGYVGPRC-EQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCP 935
Query: 209 DGFTGEDCSQLACPS-----DCNDQGKC--------VNGVCICFEGYAGADCSREICPV- 254
G+ G C ACP+ DC C VNG C+C G G C+ E CP
Sbjct: 936 AGWRGTFCEH-ACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCA-ETCPAH 993
Query: 255 ----------------PCSEEHGTC--------VDGLCVCHDGFAGDDCNKPLCLNNCYN 290
C HG C L C G GD+C CL C N
Sbjct: 994 TYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHS-CL--CQN 1050
Query: 291 RGRC--VENECVCDEGFTGEDCSELICPND----CFDRGRCING--------TCYCEEGF 336
G C V C C EG+ G C + P D C G C+NG C C G+
Sbjct: 1051 GGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGW 1110
Query: 337 TGEDCGKP--------------TCPH--ACHTQGRCEEGQCVCDEGFAGVDCSEKRCPA- 379
TG+ C P +CP ACH G C C GF G C E+ CP
Sbjct: 1111 TGDKCQSPCLRGWFGEACAQRCSCPPGAACHHV----TGACRCPPGFTGSGC-EQACPPG 1165
Query: 380 ----DCHNRGRC---------VDGRCECDDGFTGADCGELKCPNGCSGHG-----RCVNG 421
DC +C G C C G+ G C + +CP G G G C+NG
Sbjct: 1166 SFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQ-RCPPGRYGPGCEQLCGCLNG 1224
Query: 422 --------QCVCDEGYTGEDCSQLRCPND-----------CHSRGRC--VEGKCVCEQGF 460
C C G+ G DC+ L CP C C V G C+C G
Sbjct: 1225 GSCDAATGACRCPTGFLGTDCN-LTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGR 1283
Query: 461 KGYDCSDMSCPND-----------CHQHGRC--VNGMCVCDDGYTGEDCRDRQCPR---- 503
G C + CP + C G C NG C C G+TG C + CP
Sbjct: 1284 AGVRC-ERGCPQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHC-ELACPPGRYG 1341
Query: 504 -------DCSNRGLC--VDGQCVCEDGFTGPDCAELSCPNDCHG---QGRC--------- 542
C N C G C C GF G C E CP HG QG C
Sbjct: 1342 AACHLECSCHNNSTCEPATGTCRCGPGFYGQAC-EHPCPPGFHGAGCQGLCWCQHGAPCD 1400
Query: 543 -VNGQCVCHEGFMGKDCKE------------QRCPSDCHGQGRC--VDGQCICHEGFTG- 586
++G+C+C GF G C+ QRC DC G C V G C+C G +G
Sbjct: 1401 PISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRC--DCDGGAPCDPVTGLCLCPPGRSGA 1458
Query: 587 ---LDC--GQH--SCP--SDCNNLGQC--VSGRCICNEGYSGEDCSEVSP 625
LDC GQ SC DC C VSG+C C +GY G C E P
Sbjct: 1459 TCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCREGGP 1508
Score = 209 bits (531), Expect = 3e-53
Identities = 185/586 (31%), Positives = 236/586 (40%), Gaps = 176/586 (30%)
Query: 206 ICDDGFTGEDCSQLACPSDCNDQGKCVNGV--CICFEGYAGADCSREICP---------V 254
+C D G DCS L C DC + G C+ G+ C C EG+ G C+ E CP
Sbjct: 510 VCLDDSFGHDCS-LTC-DDCRNGGTCLLGLDGCDCPEGWTGLICN-ETCPPDTFGKNCSF 566
Query: 255 PCS-EEHGTC--VDGLCVCHDGFAGDDCN------------KPLCLNNCYNRGRC--VEN 297
CS + GTC V G C C G +G +C + C NC NRGRC +
Sbjct: 567 SCSCQNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKC--NCANRGRCHRLYG 624
Query: 298 ECVCDEGFTGEDCSELICPNDCFDRG-----RCI----------NGTCYCEEGFTGEDCG 342
C+CD G G C L CP F G +C+ +G+C C+ GF GE C
Sbjct: 625 ACLCDPGLYGRFC-HLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQ 683
Query: 343 K--------PTCPHACHTQG--RCEE--GQCV--CDEGFAGVDCSEKRCPA-----DCHN 383
P C AC C+ G+C C GF G DC ++ CP +C +
Sbjct: 684 AECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQE-CPVGTFGVNCSS 742
Query: 384 RGRC-------VDGRCECDDGFTGADCGELKCPNG------------CSGHGRC--VNGQ 422
C V G+C C G TG DC E CP G C RC G
Sbjct: 743 SCSCGGAPCHGVTGQCRCPPGRTGEDC-EADCPEGRWGLGCQEICPACQHAARCDPETGA 801
Query: 423 CVCDEGYTGEDCS------------QLRCPNDCHSRGRC--VEGKCVCEQGFKGYDCS-- 466
C+C G+ G C Q RC C + G C G C C G+ G+ C
Sbjct: 802 CLCLPGFVGSRCQDVCPAGWYGPSCQTRC--SCANDGHCHPATGHCSCAPGWTGFSCQRA 859
Query: 467 --------DMSCPNDCHQ-HGRC--VNGMCVCDDGYTGEDCRDRQCPRD-----CSNRGL 510
D S P +C HG C ++G+C+C+ GY G C ++QCP+ C R
Sbjct: 860 CDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRC-EQQCPQGHFGPGCEQRCQ 918
Query: 511 C--------VDGQCVCEDGFTGPDCAELSCPN-----DCHGQGRC--------VNGQCVC 549
C V G C C G+ G C E +CP DC C VNG C+C
Sbjct: 919 CQHGAACDHVSGACTCPAGWRGTFC-EHACPAGFFGLDCRSACNCTAGAACDAVNGSCLC 977
Query: 550 HEGFMGKDCKEQRCPSDCHGQG-----------RC--VDGQCICHEGFTGLDCGQHSCPS 596
G G C E CP+ +G C V GQC C G+ G C Q +CP+
Sbjct: 978 PAGRRGPRCAET-CPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQ-ACPA 1035
Query: 597 D-----------CNNLGQC--VSGRCICNEGYSGEDCSEVSPPKDL 629
C N G C VSG C C EG++G C + P+D+
Sbjct: 1036 GLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEKECLPRDV 1081
Score = 187 bits (476), Expect = 8e-47
Identities = 171/564 (30%), Positives = 207/564 (36%), Gaps = 163/564 (28%)
Query: 140 CTAGAGC------CLQPATGRLDTRPFCSGR------GNFSTEGCGCV------------ 175
CTAGA C CL PA R P C+ G+ ++ C C
Sbjct: 962 CTAGAACDAVNGSCLCPAGRR---GPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQC 1018
Query: 176 -CEPGWKGPNCSEPECPGN-----------CHLRGRC--IDGQCICDDGFTGEDCSQLAC 221
C PGW GP+C + CP C G C + G C C +G+ G C +
Sbjct: 1019 HCAPGWMGPSCLQA-CPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEKECL 1077
Query: 222 PSD----CNDQGKCVNGV--------CICFEGYAGADCSR--------EICPVPCSEEHG 261
P D C G C+NG C+C G+ G C E C CS G
Sbjct: 1078 PRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPG 1137
Query: 262 TC---VDGLCVCHDGFAGDDCNKPL--------CLNNCYNRGR---C--VENECVCDEGF 305
V G C C GF G C + C C G C C C G+
Sbjct: 1138 AACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAGY 1197
Query: 306 TGEDCSELICPN----------DCFDRGRC--INGTCYCEEGFTGEDCGK--------PT 345
G C + P C + G C G C C GF G DC P
Sbjct: 1198 HGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPN 1257
Query: 346 CPHACHT-QGR-CEE--GQCVCDEGFAGVDCSEKRCPAD-----------CHNRGRC--V 388
C H C QG C+ G C+C G AGV C E+ CP + C N G C
Sbjct: 1258 CTHVCGCGQGAACDPVTGTCLCPPGRAGVRC-ERGCPQNRFGVGCEHTCSCRNGGLCHAS 1316
Query: 389 DGRCECDDGFTGADCGELKCPNG-----------CSGHGRC--VNGQCVCDEGYTGEDCS 435
+G C C G+TG C EL CP G C + C G C C G+ G+ C
Sbjct: 1317 NGSCSCGLGWTGRHC-ELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACE 1375
Query: 436 QLRCPNDCHSRGRCVEGKCVCEQGFKGYDCSDMS----CPNDCHQHGRCVNGMCVCDDGY 491
CP H G +G C C+ G C +S CP H H C G C+ G
Sbjct: 1376 H-PCPPGFHGAG--CQGLCWCQHGAP---CDPISGRCLCPAGFHGHF-CERG---CEPGS 1425
Query: 492 TGEDCRDRQCPRDCSNRGLC--VDGQCVCEDGFTGPDCAELSCPN-----------DCHG 538
GE C R C DC C V G C+C G +G C L C DC G
Sbjct: 1426 FGEGCHQR-C--DCDGGAPCDPVTGLCLCPPGRSGATC-NLDCRRGQFGPSCTLHCDCGG 1481
Query: 539 QGRC--VNGQCVCHEGFMGKDCKE 560
C V+GQC C +G+MG C+E
Sbjct: 1482 GADCDPVSGQCHCVDGYMGPTCRE 1505
Score = 124 bits (310), Expect = 1e-27
Identities = 164/616 (26%), Positives = 214/616 (34%), Gaps = 194/616 (31%)
Query: 174 CVCEPGWKGPNC--SEPEC---PGNCHLRGRCIDGQ----CICDDGFTGEDCSQ--LACP 222
C C PG++GP C EC G C + RC++ C C GF S+ LA
Sbjct: 147 CHCPPGFQGPRCQYDVDECRTHNGGC--QHRCVNTPGSYLCECKPGFRLHTDSRTCLAIN 204
Query: 223 SDCNDQGKCVNGV---------CICFEGYA----GADCSREICPVPCSEEHGTC------ 263
S G C + C C G+ G C R PC+ +G+C
Sbjct: 205 SCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRR---SPCANRNGSCMHRCQV 261
Query: 264 VDGL--CVCHDGFA----------GDDCNKPL--CLNNCYNRGRCVENECVCDEGF---- 305
V GL C CH G+ D+C L C + C N +CVC G+
Sbjct: 262 VRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQGSF--KCVCHAGYELGA 319
Query: 306 TGEDC--SELICPNDC-FDRGRCINGTCYCEEGFTGEDCGKPTCP---------HACHTQ 353
G C E+ N C + G C +G C G C TCP C
Sbjct: 320 DGRQCYRIEMEIVNSCEANNGGCSHG---CSHTSAGPLC---TCPRGYELDTDQRTCIDV 373
Query: 354 GRCEEGQC---VCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECDDGFTGADCGELKCPN 410
C + C VC G +C C+ R C C+D +C +
Sbjct: 374 DDCADSPCCQQVCTNNPGGYECG-------CYAGYRLSADGCGCED---VDECASSR--G 421
Query: 411 GCSGHGRCVNG--QCVCDEGYTGED----CSQLRCP------------------------ 440
GC H + G QC C+ GY + CS L P
Sbjct: 422 GCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDEL 481
Query: 441 -------------NDCHSRG-RCVEGKCVCEQGFKGYDCSDMSCPNDCHQHGRCVNGM-- 484
+ RG + K VC G+DCS ++C +DC G C+ G+
Sbjct: 482 PQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCS-LTC-DDCRNGGTCLLGLDG 539
Query: 485 CVCDDGYTGEDCRDRQCPRD-----------CSNRGLC--VDGQCVCEDGFTGPDCAELS 531
C C +G+TG C + CP D C N G C V G C C G +G +C E
Sbjct: 540 CDCPEGWTGLICNE-TCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSGTNC-EDG 597
Query: 532 CPN-----------DCHGQGRC--VNGQCVCHEGFMGKDCKEQRCPSDCHGQG-----RC 573
CP +C +GRC + G C+C G G+ C CP G G +C
Sbjct: 598 CPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFC-HLTCPPWAFGPGCSEECQC 656
Query: 574 V----------DGQCICHEGFTGLDCGQ------------HSCPSDCNNLGQCVSGRC-- 609
V DG C C GF G C +C VSG C
Sbjct: 657 VQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGK 716
Query: 610 ICNEGYSGEDCSEVSP 625
C G+ GEDC + P
Sbjct: 717 RCPAGFQGEDCGQECP 732
Score = 45.8 bits (107), Expect = 5e-04
Identities = 53/181 (29%), Positives = 65/181 (35%), Gaps = 39/181 (21%)
Query: 479 RCVNGMCVCDDGYTGEDCRDRQCPRD-CSNRGLCVDGQ---CVCEDGFTGPDCAELSCPN 534
RC G D E C +C C + G CV G C C GF GP C
Sbjct: 109 RCCRGWMQQPDE---EGCLSAECSASLCFHGGRCVPGSAQPCHCPPGFQGPRCQYDVDEC 165
Query: 535 DCHGQG---RCVNGQ----CVCHEGF-MGKDCKEQRCPSDCH-GQGRC---------VDG 576
H G RCVN C C GF + D + + C G G C
Sbjct: 166 RTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRH 225
Query: 577 QCICHEGFTGLDCGQHSC-PSDC-NNLGQCVS--------GRCICNEGY----SGEDCSE 622
+C C GF + G+H S C N G C+ RC C+ GY G+ C +
Sbjct: 226 RCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACED 285
Query: 623 V 623
V
Sbjct: 286 V 286
>gi|21704277 jagged 2 isoform a precursor [Homo sapiens]
Length = 1238
Score = 218 bits (555), Expect = 5e-56
Identities = 193/646 (29%), Positives = 255/646 (39%), Gaps = 172/646 (26%)
Query: 143 GAGCCLQPATGRLDTRPFCSGRGNFSTEGCG----CVCEPGWKGPNCSE----PEC---- 190
G C+ G+ C N GC C C GW+G C E P C
Sbjct: 227 GNKACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGRFCDECVPYPGCVHGS 286
Query: 191 ---PGNCHLR------------------------GRCIDGQ-----CICDDGFTGEDC-- 216
P C+ G CI+ + C C DG++G +C
Sbjct: 287 CVEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEK 346
Query: 217 SQLACPSD-CNDQGKC----VNGVCICFEGYAGADCSREI---CPVPCSEEHGTCVDGL- 267
++ AC S+ C + G C C C G++G C+ +I PC+ GTCVD +
Sbjct: 347 AEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCA-AGGTCVDQVD 405
Query: 268 ---CVCHDGFAG-------DDCNKPLCLNNCYNRGRCVENECVCDEGFTGEDCSELICPN 317
C+C + + G ++C CLN + C C G+ G +C I N
Sbjct: 406 GFECICPEQWVGATCQLDANECEGKPCLNAFSCKNLIGGYYCDCIPGWKGINCH--INVN 463
Query: 318 DCFDRGRCING----------TCYCEEGFTGEDC--GKPTCPHA-CHTQGRCEE----GQ 360
DC RG+C +G C C GF G C + C + CH+ G CE+
Sbjct: 464 DC--RGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFH 521
Query: 361 CVCDEGFAGVDCS---EKRCPADCHNRGRCV----DGRCECDDGFTGADCGELK--CPNG 411
C C +GF+G C + P+ C N RC D C C D F G +C + CP G
Sbjct: 522 CHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGG 581
Query: 412 ------------------------CSGHGRCV-----NGQCVCDEGYTGEDCSQ-----L 437
C HGRCV N C+CD G+TG C + L
Sbjct: 582 ACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCL 641
Query: 438 RCPNDCHSRGRCVEG----KCVCEQGFKGYDCS---DMSCPNDCHQHGRC---VNGM-CV 486
P C + G C++ +C C G++G C + P+ CH GRC VN C
Sbjct: 642 GQP--CRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCA 699
Query: 487 CDDGYTGEDCRDRQCPRD---CSNRGLCVDG----QCVCEDGFTGPDCA---ELSC-PND 535
CDDG+ G+ C R+ D CSN G C D +C C G+ G CA SC PN
Sbjct: 700 CDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNP 759
Query: 536 CHGQGRCVNG----QCVCHEGFMGKDCKEQR--C-PSDCHGQGRCVDG----QCICHEGF 584
C G CV C+C +G+ G+ C C P C+ G CVDG +C C GF
Sbjct: 760 CVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGF 819
Query: 585 TGLDC--GQHSCPSD-CNNLGQCVSG----RCICNEGYSGEDCSEV 623
G DC C S C CV RC C G +G C EV
Sbjct: 820 AGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEV 865
Score = 195 bits (495), Expect = 5e-49
Identities = 179/590 (30%), Positives = 238/590 (40%), Gaps = 136/590 (23%)
Query: 171 GCGCVCEPGWKGPNCS--EPECPGN-CHLRGRCIDG----QCICDDGFTGEDCSQLACPS 223
G C C GW GP C+ EC N C G C+D +CIC + + G C A
Sbjct: 368 GFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDANEC 427
Query: 224 D---CNDQGKCVNGV----CICFEGYAGADCSREI--CPVPCSEEHGTCVDGL----CVC 270
+ C + C N + C C G+ G +C + C C + GTC D + CVC
Sbjct: 428 EGKPCLNAFSCKNLIGGYYCDCIPGWKGINCHINVNDCRGQC-QHGGTCKDLVNGYQCVC 486
Query: 271 HDGFAGDDC--NKPLCLNN-CYNRGRCVE----NECVCDEGFTGEDCS---ELICPNDCF 320
GF G C + C ++ C++ G C + C C +GF+G C +L P+ C
Sbjct: 487 PRGFGGRHCELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCR 546
Query: 321 DRGRCIN----GTCYCEEGFTGEDCGKP--TCP------------------------HAC 350
+ RC N C C + F G++C P CP C
Sbjct: 547 NGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVC 606
Query: 351 HTQGRCEEG-----QCVCDEGFAGVDCSEK--RCPAD-CHNRGRCVDG----RCECDDGF 398
GRC C+CD GF G C E C C N G C+D RC C G+
Sbjct: 607 GPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGW 666
Query: 399 TG--ADCGELKC-PNGCSGHGRC---VNG-QCVCDEGYTGEDCSQLRCPND---CHSRGR 448
G D C P+ C GRC VN C CD+G+ G+ C D C + G
Sbjct: 667 EGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGT 726
Query: 449 CVEG----KCVCEQGFKGYDCS---DMSC-PNDCHQHGRCVNG----MCVCDDGYTGEDC 496
C + +C C G+KG C+ + SC PN C G CV C+C DG+ G C
Sbjct: 727 CYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTC 786
Query: 497 --RDRQC-PRDCSNRGLCVDG----QCVCEDGFTGPDC---AELSCPNDCHGQGRCV--- 543
C P C N G+CVDG +C C GF GPDC + + C CV
Sbjct: 787 THNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEI 846
Query: 544 NG-QCVCHEGFMGKDCKE-----QRCPS-------------DCHGQGRCVDGQCICHEGF 584
NG +C C G G C+E + C S DC+ RC+DG+ C + +
Sbjct: 847 NGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHGSSWVEDCN-SCRCLDGRRDCSKVW 905
Query: 585 TG----LDCGQHSCPSDCNNLGQ-CVS---GRCICNEGYSGEDCSEVSPP 626
G L GQ S LGQ C+ G+C+ + +C PP
Sbjct: 906 CGWKPCLLAGQPEALSAQCPLGQRCLEKAPGQCLRPPCEAWGECGAEEPP 955
Score = 184 bits (467), Expect = 8e-46
Identities = 172/612 (28%), Positives = 229/612 (37%), Gaps = 158/612 (25%)
Query: 140 CTAGAGC--------CLQP-----ATGRLDTRPFCSGRGNFSTEGCG-------CVCEPG 179
C AG C C+ P AT +LD C G+ + C C C PG
Sbjct: 394 CAAGGTCVDQVDGFECICPEQWVGATCQLDANE-CEGKPCLNAFSCKNLIGGYYCDCIPG 452
Query: 180 WKGPNC--SEPECPGNCHLRGRCID----GQCICDDGFTGEDCS---QLACPSDCNDQGK 230
WKG NC + +C G C G C D QC+C GF G C S C+ G
Sbjct: 453 WKGINCHINVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGL 512
Query: 231 CVNGV----CICFEGYAGADCSREI--C-PVPCSEEHGTCV----DGLCVCHDGFAGDDC 279
C + C C +G++G C ++ C P PC C D C C D F G +C
Sbjct: 513 CEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPC-RNGARCYNLEGDYYCACPDDFGGKNC 571
Query: 280 NKP--------------------------LCLNNCYNRGRCVEN-----ECVCDEGFTGE 308
+ P C GRCV C+CD GFTG
Sbjct: 572 SVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGT 631
Query: 309 DCSELI---CPNDCFDRGRCINGT----CYCEEGFTGEDCG---KPTCPHACHTQGRC-- 356
C E I C + G CI+ C+C G+ GE C P CH++GRC
Sbjct: 632 YCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYD 691
Query: 357 --EEGQCVCDEGFAGVDCSEKRCPAD---CHNRGRCVDG----RCECDDGFTGADCGELK 407
+ C CD+G+ G C + D C N G C D RC C G+ G+ C K
Sbjct: 692 LVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAK 751
Query: 408 ----CPNGCSGHGRCVNG----QCVCDEGYTGEDCSQLR--C-PNDCHSRGRCVEG---- 452
PN C G CV C+C +G+ G C+ C P C++ G CV+G
Sbjct: 752 NSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWF 811
Query: 453 KCVCEQGFKGYDCS---DMSCPNDCHQHGRCV---NG-MCVCDDGYTGEDCRD-RQCPRD 504
+C C GF G DC D + C CV NG C C G G C++ R
Sbjct: 812 RCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRS 871
Query: 505 CSNRGLCVD---------GQCVCEDGFTGPDCAELSC---PNDCHGQGRCVNGQCVCHEG 552
C +RG C C DG DC+++ C P GQ ++ QC
Sbjct: 872 CWSRGTPFPHGSSWVEDCNSCRCLDG--RRDCSKVWCGWKPCLLAGQPEALSAQCP---- 925
Query: 553 FMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLDCGQHSCPSDCNNLGQCVSGRCICN 612
+G+ C E+ GQC+ +CG PS C+
Sbjct: 926 -LGQRCLEK------------APGQCLRPPCEAWGECGAEEPPST----------PCLPR 962
Query: 613 EGYSGEDCSEVS 624
G+ +C+ ++
Sbjct: 963 SGHLDNNCARLT 974
Score = 58.9 bits (141), Expect = 5e-08
Identities = 45/149 (30%), Positives = 61/149 (40%), Gaps = 44/149 (29%)
Query: 518 CEDGFTGPDCAELSCP-NDCHGQGRCVN-GQCVCHEGFMGKDCKEQRCPSDC---HG--- 569
C++ + C + P ND G C G C +G+MGK+CKE C C HG
Sbjct: 198 CDENYYSATCNKFCRPRNDFFGHYTCDQYGNKACMDGWMGKECKEAVCKQGCNLLHGGCT 257
Query: 570 -----------QGR----------CVDGQCI------CHEGFTGLDCGQ--HSCPS--DC 598
QGR CV G C+ C + GL C + + C S C
Sbjct: 258 VPGECRCSYGWQGRFCDECVPYPGCVHGSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPC 317
Query: 599 NNLGQCVSG-----RCICNEGYSGEDCSE 622
N G C++ RC C +GYSG +C +
Sbjct: 318 TNGGTCINAEPDQYRCTCPDGYSGRNCEK 346
Score = 43.5 bits (101), Expect = 0.002
Identities = 26/81 (32%), Positives = 35/81 (43%), Gaps = 4/81 (4%)
Query: 549 CHEGFMGKDCKEQRCP-SDCHGQGRCVD-GQCICHEGFTGLDCGQHSCPSDCNNL--GQC 604
C E + C + P +D G C G C +G+ G +C + C CN L G
Sbjct: 198 CDENYYSATCNKFCRPRNDFFGHYTCDQYGNKACMDGWMGKECKEAVCKQGCNLLHGGCT 257
Query: 605 VSGRCICNEGYSGEDCSEVSP 625
V G C C+ G+ G C E P
Sbjct: 258 VPGECRCSYGWQGRFCDECVP 278
>gi|122937343 platelet endothelial aggregation receptor 1 [Homo
sapiens]
Length = 1037
Score = 216 bits (551), Expect = 2e-55
Identities = 183/624 (29%), Positives = 235/624 (37%), Gaps = 186/624 (29%)
Query: 174 CVCEPGWKGPNCSE--------PEC--PGNCHLRGRC--IDGQCICDDGFTGEDCSQLAC 221
C C PGW+G +CS P+C P +C C G C C G +C Q
Sbjct: 120 CQCVPGWRGDDCSSECAPGMWGPQCDKPCSCGNNSSCDPKSGVCSCPSGLQPPNCLQPCT 179
Query: 222 PS----DCNDQGKC-------VNGVCICFEGYAGADC--------SREICPVPCSEEHG- 261
P C + +C G C C G C S CP S ++G
Sbjct: 180 PGYYGPACQFRCQCHGAPCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGG 239
Query: 262 --TCVDGLCVCHDGFAGDDCNKPL--------CLN--NCYNRGRC--VENECVCDEGFTG 307
G C C G+ G C+ P C C+N G C +C C G+TG
Sbjct: 240 VFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAPGYTG 299
Query: 308 EDCSELICP-----------NDCFDRGRCI--NGTCYCEEGFTGEDCGKPTCPH-----A 349
+ C E CP DC RC NG C CE GFTG+ C CP +
Sbjct: 300 DRCRE-ECPVGRFGQDCAETCDCAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLS 358
Query: 350 CHTQGRCE----------EGQCVCDEGFAGVDCSEKRCPADCHNRG-------------R 386
C C+ G+C C G+AG+ C+E CP D H G +
Sbjct: 359 CQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCNES-CPQDTHGPGCQEHCLCLHGGVCQ 417
Query: 387 CVDGRCECDDGFTGADCGELKCPN----GCSGHGRC--------VNGQCVCDEGYTGEDC 434
G C+C G+TG C L P+ CS C ++G+CVC EG+ +C
Sbjct: 418 ATSGLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNC 477
Query: 435 SQLRCPN-----DCHSRGRCVE--------GKCVCEQGFKGYDCSDMSCPN--------- 472
S + CP C++ +C G C C G+ G C + CP
Sbjct: 478 S-VPCPPGTWGFSCNASCQCAHEAVCSPQTGACTCTPGWHGAHC-QLPCPKGQFGEGCAS 535
Query: 473 --DCHQHGRC--VNGMCVCDDGYTGEDCRDRQCPR-----------DCSNRGLCV--DGQ 515
DC C V+G C C G+ G C CP C N G C+ +G
Sbjct: 536 RCDCDHSDGCDPVHGRCQCQAGWMGARCH-LSCPEGLWGVNCSNTCTCKNGGTCLPENGN 594
Query: 516 CVCEDGFTGPDCAELSCPNDCHGQGRCV-------------NGQCVCHEGFMGKDCKEQR 562
CVC GF GP C + SC +G+ RCV NG C C G+ G DC Q
Sbjct: 595 CVCAPGFRGPSC-QRSCQPGRYGK-RCVPCKCANHSFCHPSNGTCYCLAGWTGPDC-SQP 651
Query: 563 CP-----------SDCHGQGRC--VDGQCICHEGFTGLDCGQHSCP-----SDCNNLGQC 604
CP CH G C DG CIC G+TG C CP ++C+ QC
Sbjct: 652 CPPGHWGENCAQTCQCHHGGTCHPQDGSCICPLGWTGHHC-LEGCPLGTFGANCSQPCQC 710
Query: 605 --------VSGRCICNEGYSGEDC 620
+G C+C G+SG C
Sbjct: 711 GPGEKCHPETGACVCPPGHSGAPC 734
Score = 210 bits (534), Expect = 1e-53
Identities = 175/581 (30%), Positives = 227/581 (39%), Gaps = 150/581 (25%)
Query: 161 CSGRGNFSTEGCGCVCEPGWKGPNCSEPECPGN----CHLRGRCID-------GQCICDD 209
C + + C C G + PNC +P PG C R +C G C C
Sbjct: 150 CGNNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPCDPQTGACFCPA 209
Query: 210 GFTGEDC--------SQLACPS--DCNDQG--KCVNGVCICFEGYAGADCSREICPVPCS 257
TG C S CPS C + G + G C C G+ G IC +PC
Sbjct: 210 ERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGT-----ICSLPCP 264
Query: 258 EE-HGTCVDGLCVCHDGFAGDDCNKPLCLNNCYNRGRCVENECVCDEGFTGEDCSELICP 316
E HG C CH+G D Y RC E C G G+DC+E
Sbjct: 265 EGFHGPNCSQECRCHNGGLCDRFTGQCRCAPGYTGDRCREE---CPVGRFGQDCAETC-- 319
Query: 317 NDCFDRGRCI--NGTCYCEEGFTGEDCGKPTCPHACHTQGRCEEGQCVCDEGFAGVDCSE 374
DC RC NG C CE GFTG+ C CP +GF G+ C +
Sbjct: 320 -DCAPDARCFPANGACLCEHGFTGDRCTDRLCP-----------------DGFYGLSC-Q 360
Query: 375 KRCPADCHNRGRC--VDGRCECDDGFTGADCGELKCPN-----GCSGHGRCVNGQ----- 422
C D + C ++G C C G+ G C E CP GC H C++G
Sbjct: 361 APCTCDREHSLSCHPMNGECSCLPGWAGLHCNE-SCPQDTHGPGCQEHCLCLHGGVCQAT 419
Query: 423 ---CVCDEGYTGEDCSQLRCPND-----CHSRGRC--------VEGKCVCEQGFKGYDCS 466
C C GYTG C+ L CP D C +R C ++G+CVC++G++ +CS
Sbjct: 420 SGLCQCAPGYTGPHCASL-CPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCS 478
Query: 467 DMSCPN-----DCHQHGRCVN--------GMCVCDDGYTGEDCRDRQCPR---------- 503
+ CP C+ +C + G C C G+ G C+ CP+
Sbjct: 479 -VPCPPGTWGFSCNASCQCAHEAVCSPQTGACTCTPGWHGAHCQ-LPCPKGQFGEGCASR 536
Query: 504 -DCSNRGLC--VDGQCVCEDGFTGPDCAELSCPND-----------CHGQGRCV--NGQC 547
DC + C V G+C C+ G+ G C LSCP C G C+ NG C
Sbjct: 537 CDCDHSDGCDPVHGRCQCQAGWMGARC-HLSCPEGLWGVNCSNTCTCKNGGTCLPENGNC 595
Query: 548 VCHEGFMGKDCKE--------QRC-PSDCHGQGRC--VDGQCICHEGFTGLDCGQHSCPS 596
VC GF G C+ +RC P C C +G C C G+TG DC Q P
Sbjct: 596 VCAPGFRGPSCQRSCQPGRYGKRCVPCKCANHSFCHPSNGTCYCLAGWTGPDCSQPCPPG 655
Query: 597 ----------DCNNLGQC--VSGRCICNEGYSGEDCSEVSP 625
C++ G C G CIC G++G C E P
Sbjct: 656 HWGENCAQTCQCHHGGTCHPQDGSCICPLGWTGHHCLEGCP 696
Score = 198 bits (504), Expect = 4e-50
Identities = 173/598 (28%), Positives = 221/598 (36%), Gaps = 173/598 (28%)
Query: 111 CGCAAAPDVKELLSRLEELENLVSSLREQCTAGAGCCLQPATGRLDTRPFCSGRGNFSTE 170
C C AP + + E S C+ G P+T C G F T
Sbjct: 191 CQCHGAPCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHS------CQNGGVFQTP 244
Query: 171 GCGCVCEPGWK-------------GPNCSEPECPGNCHLRGRC--IDGQCICDDGFTGED 215
C C PGW GPNCS+ EC CH G C GQC C G+TG+
Sbjct: 245 QGSCSCPPGWMGTICSLPCPEGFHGPNCSQ-EC--RCHNGGLCDRFTGQCRCAPGYTGDR 301
Query: 216 CSQLACP-----------SDCNDQGKC--VNGVCICFEGYAGADCSREIC---------- 252
C + CP DC +C NG C+C G+ G C+ +C
Sbjct: 302 CRE-ECPVGRFGQDCAETCDCAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQ 360
Query: 253 -PVPCSEEHG-TC--VDGLCVCHDGFAGDDCNK--------PLCLNN--CYNRGRC--VE 296
P C EH +C ++G C C G+AG CN+ P C + C + G C
Sbjct: 361 APCTCDREHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATS 420
Query: 297 NECVCDEGFTGEDCSELICPND-----CFDRGRC--------INGTCYCEEGFTGEDCGK 343
C C G+TG C+ L CP D C R C I+G C C+EG+ +C
Sbjct: 421 GLCQCAPGYTGPHCASL-CPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSV 479
Query: 344 PTCP-----HACHTQGRC--------EEGQCVCDEGFAGVDCSEKRCP-----------A 379
P CP +C+ +C + G C C G+ G C + CP
Sbjct: 480 P-CPPGTWGFSCNASCQCAHEAVCSPQTGACTCTPGWHGAHC-QLPCPKGQFGEGCASRC 537
Query: 380 DCHNRGRC--VDGRCECDDGFTGADCGELKCPNG-----------CSGHGRCV--NGQCV 424
DC + C V GRC+C G+ GA C L CP G C G C+ NG CV
Sbjct: 538 DCDHSDGCDPVHGRCQCQAGWMGARC-HLSCPEGLWGVNCSNTCTCKNGGTCLPENGNCV 596
Query: 425 CDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCEQGFKGYDCSDMSCPNDCHQHGRCVNGM 484
C G+ G C + C+ G G C C N H NG
Sbjct: 597 CAPGFRGPSCQR------------------SCQPGRYGKRCVPCKCAN--HSFCHPSNGT 636
Query: 485 CVCDDGYTGEDCRDRQCPR-----------DCSNRGLC--VDGQCVCEDGFTGPDCAELS 531
C C G+TG DC + CP C + G C DG C+C G+TG C E
Sbjct: 637 CYCLAGWTGPDC-SQPCPPGHWGENCAQTCQCHHGGTCHPQDGSCICPLGWTGHHCLE-G 694
Query: 532 CPNDCHGQGRCVNGQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLDC 589
CP G + C C G CH + G C+C G +G C
Sbjct: 695 CPLGTFGAN--CSQPCQCGPG------------EKCHPE----TGACVCPPGHSGAPC 734
Score = 188 bits (477), Expect = 6e-47
Identities = 171/610 (28%), Positives = 228/610 (37%), Gaps = 169/610 (27%)
Query: 176 CEPGWKGPN-CSEPECPGNCHLRGRCIDG-----QCICDDGFTGEDCSQLACPSDCNDQG 229
CE W+GP+ C +P R QC C + C +C G
Sbjct: 55 CERPWEGPHTCPQPTVVYRTVYRQVVKTDHRQRLQC-CHGFYESRGFCVPLCAQECV-HG 112
Query: 230 KCVN-GVCICFEGYAGADCSREI--------CPVPCSEEHGTCVD---GLCVCHDGFAGD 277
+CV C C G+ G DCS E C PCS + + D G+C C G
Sbjct: 113 RCVAPNQCQCVPGWRGDDCSSECAPGMWGPQCDKPCSCGNNSSCDPKSGVCSCPSGLQPP 172
Query: 278 DCNKPL--------CLNNCYNRGRCVENE---CVCDEGFTGEDC--------SELICPN- 317
+C +P C C G + + C C TG C S CP+
Sbjct: 173 NCLQPCTPGYYGPACQFRCQCHGAPCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPST 232
Query: 318 -DCFDRG--RCINGTCYCEEGFTGEDCGKPTCPHA-----------CHTQGRCEE--GQC 361
C + G + G+C C G+ G C P CP CH G C+ GQC
Sbjct: 233 HSCQNGGVFQTPQGSCSCPPGWMGTICSLP-CPEGFHGPNCSQECRCHNGGLCDRFTGQC 291
Query: 362 VCDEGFAGVDCSEKRCPA-----------DCHNRGRC--VDGRCECDDGFTGADCGELKC 408
C G+ G C E+ CP DC RC +G C C+ GFTG C + C
Sbjct: 292 RCAPGYTGDRCREE-CPVGRFGQDCAETCDCAPDARCFPANGACLCEHGFTGDRCTDRLC 350
Query: 409 PNG-----CSGHGRC----------VNGQCVCDEGYTGEDCSQLRCPNDCHSRG------ 447
P+G C C +NG+C C G+ G C++ CP D H G
Sbjct: 351 PDGFYGLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCNE-SCPQDTHGPGCQEHCL 409
Query: 448 -------RCVEGKCVCEQGFKGYDCSDMSCPNDCHQ---HGRC----------VNGMCVC 487
+ G C C G+ G C+ + CP D + RC ++G CVC
Sbjct: 410 CLHGGVCQATSGLCQCAPGYTGPHCASL-CPPDTYGVNCSARCSCENAIACSPIDGECVC 468
Query: 488 DDGYTGEDCRDRQCPR-----------DCSNRGLCVD--GQCVCEDGFTGPDCAELSCPN 534
+G+ +C CP C++ +C G C C G+ G C +L CP
Sbjct: 469 KEGWQRGNC-SVPCPPGTWGFSCNASCQCAHEAVCSPQTGACTCTPGWHGAHC-QLPCPK 526
Query: 535 DCHGQG---RC----------VNGQCVCHEGFMGKDCKEQRCPSD-----------CHGQ 570
G+G RC V+G+C C G+MG C CP C
Sbjct: 527 GQFGEGCASRCDCDHSDGCDPVHGRCQCQAGWMGARC-HLSCPEGLWGVNCSNTCTCKNG 585
Query: 571 GRCV--DGQCICHEGFTGLDCGQHSC----------PSDCNNLGQC--VSGRCICNEGYS 616
G C+ +G C+C GF G C Q SC P C N C +G C C G++
Sbjct: 586 GTCLPENGNCVCAPGFRGPSC-QRSCQPGRYGKRCVPCKCANHSFCHPSNGTCYCLAGWT 644
Query: 617 GEDCSEVSPP 626
G DCS+ PP
Sbjct: 645 GPDCSQPCPP 654
Score = 176 bits (447), Expect = 2e-43
Identities = 149/489 (30%), Positives = 191/489 (39%), Gaps = 137/489 (28%)
Query: 270 CHDGFAGDDCNKPLCLNNCYNRGRCVE-NECVCDEGFTGEDCSELICPN----------D 318
CH + PLC C + GRCV N+C C G+ G+DCS P
Sbjct: 91 CHGFYESRGFCVPLCAQECVH-GRCVAPNQCQCVPGWRGDDCSSECAPGMWGPQCDKPCS 149
Query: 319 CFDRGRC--INGTCYCEEGFTGEDCGKPTCP----HACHTQGRC-------EEGQCVCDE 365
C + C +G C C G +C +P P AC + +C + G C C
Sbjct: 150 CGNNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPCDPQTGACFCPA 209
Query: 366 GFAG----VDCSEKR----CPA--DCHNRG--RCVDGRCECDDGFTGADCGELKCPNG-- 411
G V CS+ CP+ C N G + G C C G+ G C L CP G
Sbjct: 210 ERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTIC-SLPCPEGFH 268
Query: 412 ---CSGHGRCVN--------GQCVCDEGYTGEDCSQLRCP-----------NDCHSRGRC 449
CS RC N GQC C GYTG+ C + CP DC RC
Sbjct: 269 GPNCSQECRCHNGGLCDRFTGQCRCAPGYTGDRCRE-ECPVGRFGQDCAETCDCAPDARC 327
Query: 450 --VEGKCVCEQGFKGYDCSDMSCPN-----DCHQHGRC----------VNGMCVCDDGYT 492
G C+CE GF G C+D CP+ C C +NG C C G+
Sbjct: 328 FPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGECSCLPGWA 387
Query: 493 GEDCRDRQCPRD-----------CSNRGLC--VDGQCVCEDGFTGPDCAELSCPNDCHG- 538
G C + CP+D C + G+C G C C G+TGP CA L CP D +G
Sbjct: 388 GLHCNE-SCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCASL-CPPDTYGV 445
Query: 539 --QGRC----------VNGQCVCHEGFMGKDCKEQRCPS-----DCHGQGRCV------- 574
RC ++G+CVC EG+ +C CP C+ +C
Sbjct: 446 NCSARCSCENAIACSPIDGECVCKEGWQRGNCSVP-CPPGTWGFSCNASCQCAHEAVCSP 504
Query: 575 -DGQCICHEGFTGLDCGQHSCPS-----------DCNNLGQC--VSGRCICNEGYSGEDC 620
G C C G+ G C Q CP DC++ C V GRC C G+ G C
Sbjct: 505 QTGACTCTPGWHGAHC-QLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGWMGARC 563
Query: 621 SEVSPPKDL 629
+S P+ L
Sbjct: 564 -HLSCPEGL 571
>gi|134244285 Notch homolog 3 [Homo sapiens]
Length = 2321
Score = 213 bits (542), Expect = 2e-54
Identities = 181/588 (30%), Positives = 231/588 (39%), Gaps = 110/588 (18%)
Query: 138 EQCTAGAGCCLQPATGRLDTRPFCSGRGNFSTEGCGCVCEPGWKGPNCSEPE--CPGNCH 195
E+C C P GR C T C C G++GP+CS P+ C
Sbjct: 74 ERCQLEDPCHSGPCAGR----GVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPCLSSPCA 129
Query: 196 LRGRCIDGQ-----CICDDGFTGEDC----SQLACPSDCNDQGKCVNGV----CICFEGY 242
RC G C C G+ G C + C G C+N C C GY
Sbjct: 130 HGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGY 189
Query: 243 AGADCSR---EICPVPCSEEHGTC-----VDGLCVCHDGFAGDDC--NKPLCL-NNCYNR 291
G C P PC GTC + C C GF G +C N C + C N
Sbjct: 190 TGPLCENPAVPCAPSPC-RNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNG 248
Query: 292 GRCVEN----ECVCDEGFTGEDCSE-----LICPNDCFDRGRCIN----GTCYCEEGFTG 338
G CV+ C C +TG+ C+E + PN C + G C N +C C G+TG
Sbjct: 249 GTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTG 308
Query: 339 E-------DCGKPTCPHACHTQGRCEEGQCVCDEGFAGVDCS-EKRCPAD-CHNRGRC-- 387
E DC C H R C C G G+ C + C ++ CH C
Sbjct: 309 ESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDT 368
Query: 388 --VDGR--CECDDGFTGADCGE--LKC---PNGCSGHGRCVNGQ----CVCDEGYTG--- 431
V+GR C C GFTG C + +C N C GRCVN Q C C GYTG
Sbjct: 369 NPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRC 428
Query: 432 ----EDCSQLRCPNDCHSRGRCVEGKCVCEQGFKGYDCS---DMSCPNDCHQHGRC---V 481
+C C N R + C+C GF G C D + C G C V
Sbjct: 429 ETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRV 488
Query: 482 NGM-CVCDDGYTGEDCR---DRQCPRDCSNRGLCVDG----QCVCEDGFTGPDC---AEL 530
NG C C G++G C+ D C N CVD +C C +GF G C +
Sbjct: 489 NGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDD 548
Query: 531 SCPNDCHGQGRCVNG----QCVCHEGFMGKDCKEQ--RCPSD-CHGQGRCVD----GQCI 579
P+ CH GRCV+G C C G+ G C+ Q C S C G+C+D C
Sbjct: 549 CSPDPCH-HGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCR 607
Query: 580 CHEGFTGLDCGQH--SCPSDCNNLGQCVSG----RCICNEGYSGEDCS 621
C G TG++C + C S+ G C G C+C G++G C+
Sbjct: 608 CPSGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCN 655
Score = 202 bits (514), Expect = 3e-51
Identities = 182/630 (28%), Positives = 247/630 (39%), Gaps = 186/630 (29%)
Query: 174 CVCEPGWKGPNCSEP--EC---PGNCHLRGRCIDG----QCICDDGFTGEDCSQ------ 218
C C P W G C+E EC P CH G C + C+C +G+TGE CSQ
Sbjct: 260 CQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCA 319
Query: 219 ------------------LACP----------------SDCNDQGKC----VNG--VCIC 238
ACP + C++ C VNG +C C
Sbjct: 320 TAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTC 379
Query: 239 FEGYAGADCSREI--CPV---PCSEEHGTCVDG----LCVCHDGFAGDDCNKPL--CLNN 287
G+ G C +++ C + PC E G CV+ LC C G+ G C + CL+
Sbjct: 380 PPGFTGGACDQDVDECSIGANPC-EHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSG 438
Query: 288 -CYNRGRCVEN----ECVCDEGFTG-------EDCSELICPND--CFDRGRCING-TCYC 332
C N+ C++ C+C GFTG ++C C N C DR +NG +C C
Sbjct: 439 PCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDR---VNGFSCTC 495
Query: 333 EEGFTG-------EDCGKPTCPHACHTQGRCEEGQCVCDEGFAGVDCSEK--RCPADCHN 383
GF+G ++C C + + + +C C EGF G C C D +
Sbjct: 496 PSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCH 555
Query: 384 RGRCVDG----RCECDDGFTGADCGE------------------------LKCPNGCSG- 414
GRCVDG C C G+TG C +CP+G +G
Sbjct: 556 HGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGV 615
Query: 415 ---------------HGRCVNG----QCVCDEGYTGEDCS---QLRCPNDCHSRGRCVEG 452
G C +G CVC G+TG C+ + C G CV+G
Sbjct: 616 NCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDG 675
Query: 453 ----KCVCEQGFKGYDCSDMS--CPNDCHQHGRCVNG----MCVCDDGYTGEDC-----R 497
+C+C G C S C ++ HG C + CVC+ G++G C R
Sbjct: 676 ENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLAR 735
Query: 498 DRQCPRDCSNRGLC-VDG---QCVCEDGFTGPDCAELS--CPNDCHGQGRCVN--GQ--- 546
D + C G C DG C C G G C LS PN C GRC + GQ
Sbjct: 736 DACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPV 795
Query: 547 CVCHEGFMGKDCKE--QRC--PSDCHGQGRCVD----GQCICHEGFTGLDCGQ--HSC-P 595
C C +G+ G C++ C P+ C G C + C CH G+TG C Q + C P
Sbjct: 796 CSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDP 855
Query: 596 SDCNNLGQCVSG----RCICNEGYSGEDCS 621
+ C N G C G C C G++G C+
Sbjct: 856 NPCLNGGSCQDGVGSFSCSCLPGFAGPRCA 885
Score = 197 bits (501), Expect = 9e-50
Identities = 172/578 (29%), Positives = 231/578 (39%), Gaps = 126/578 (21%)
Query: 171 GCGCVCEPGWKGPNCSE----PECPGN-CHLRGRC-IDG---QCICDDGFTGEDCSQLA- 220
G CVCEPGW GP CS+ C C G C DG C C G G C L+
Sbjct: 715 GFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSP 774
Query: 221 -CPSDCNDQGKCVNG-----VCICFEGYAGADCSREI--C--PVPCSEEHGTCVD----G 266
P+ C G+C + VC C +G+ G C +++ C P PC HG C +
Sbjct: 775 CTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCG-PHGICTNLAGSF 833
Query: 267 LCVCHDGFAGDDCNKPL--C-LNNCYNRGRCVEN----ECVCDEGFTGEDCSELI--CPN 317
C CH G+ G C++ + C N C N G C + C C GF G C+ + C +
Sbjct: 834 SCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLS 893
Query: 318 DCFDRGRCING----TCYCEEGFTGEDCGK--PTC-PHACHTQGRCEEG----QCVCDEG 366
+ G C + TC C G+ G C + P C P +C G C +G C+C G
Sbjct: 894 NPCGPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPG 953
Query: 367 FAGVDCSEKRCPA---DCHNRGRCVDG----RCECDDGFTGADCGELK---CPNGCSGHG 416
+ G C + P C + G C RC C + FTG C L C G
Sbjct: 954 YTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGG 1013
Query: 417 RCV--NGQCVCDEGYTGEDCS-------------QLRCPNDCHSRGRCVEGK----CVCE 457
RCV C+C G++G C +R C + G+CV+ CVC
Sbjct: 1014 RCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCP 1073
Query: 458 QGFKGYDCS---DMSCPNDCHQHGRCVNG-----MCVCDDGYTGEDCRD--RQC-PRDCS 506
+G G C D C QHG G MC C GY G++C D +C + C
Sbjct: 1074 EGRTGSHCEQEVDPCLAQPC-QHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQ 1132
Query: 507 NRGLCVD----GQCVCEDGFTGPDCA--ELSC----PND----CHGQGRCVN----GQCV 548
+ G C+D C C G G C E C P D C G CV+ +C
Sbjct: 1133 HGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCT 1192
Query: 549 CHEGFMGKDCKE--QRCPSD-CHGQGR--CVDG-----QCICHEGFTGLDCGQHSCPSD- 597
C G+ G C+ C S CH C+ +C+CH GF+G C P +
Sbjct: 1193 CPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCES 1252
Query: 598 --CNNLGQC---------VSGRCICNEGYSGEDCSEVS 624
C + GQC ++ C C + + G C V+
Sbjct: 1253 QPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVA 1290
Score = 188 bits (477), Expect = 6e-47
Identities = 176/567 (31%), Positives = 214/567 (37%), Gaps = 150/567 (26%)
Query: 182 GPNCSEPECPGN--CHLRGRCI-----DGQCICDDGFTGEDCSQLACPSDCNDQGKCVNG 234
GP + P C C GRC + C+C G+ GE C QL P C +G
Sbjct: 35 GPGAAAPPCLDGSPCANGGRCTQLPSREAACLCPPGWVGERC-QLEDP--------CHSG 85
Query: 235 VCICFEGYAGADCSREICPVPCSEEHGTCVDGLCVCHDGFAGDDCNKP-LCLNN-CYNRG 292
C R +C S GT C C GF G DC+ P CL++ C +
Sbjct: 86 PC----------AGRGVCQ--SSVVAGTARFS-CRCPRGFRGPDCSLPDPCLSSPCAHGA 132
Query: 293 RCVENE-----CVCDEGFTGEDC----SELICPNDCFDRGRCINGT----CYCEEGFTGE 339
RC C C G+ G C E C G C+N C C G+TG
Sbjct: 133 RCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGP 192
Query: 340 DCGKPTCPHA---CHTQGRCEEG-----QCVCDEGFAGVDCSEK--RCPAD-CHNRGRCV 388
C P P A C G C + C C GF G +C CP C N G CV
Sbjct: 193 LCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCV 252
Query: 389 DG----RCECDDGFTGADCGEL--KC---PNGCSGHGRCVNG----QCVCDEGYTGEDCS 435
DG C+C +TG C E +C PN C G C N CVC G+TGE CS
Sbjct: 253 DGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCS 312
Query: 436 Q------------------------LRCP----------------NDCHSRGRC----VE 451
Q CP N CH C V
Sbjct: 313 QNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVN 372
Query: 452 GK--CVCEQGFKGYDCSD--MSC---PNDCHQHGRCVNG----MCVCDDGYTGEDCRD-- 498
G+ C C GF G C C N C GRCVN +C C GYTG C
Sbjct: 373 GRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDV 432
Query: 499 RQC-PRDCSNRGLCVD--GQ--CVCEDGFTGPDC---AELSCPNDCHGQGRC---VNG-Q 546
+C C N+ C+D GQ C+C GFTG C + + C G C VNG
Sbjct: 433 NECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFS 492
Query: 547 CVCHEGFMGKDCK---EQRCPSDCHGQGRCVDG----QCICHEGFTGLDCGQH--SCPSD 597
C C GF G C+ ++ + C +CVD +C C EGF G C ++ C D
Sbjct: 493 CTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPD 552
Query: 598 CNNLGQCVSG----RCICNEGYSGEDC 620
+ G+CV G C C GY+G C
Sbjct: 553 PCHHGRCVDGIASFSCACAPGYTGTRC 579
Score = 176 bits (446), Expect = 2e-43
Identities = 186/702 (26%), Positives = 245/702 (34%), Gaps = 230/702 (32%)
Query: 142 AGAGCCLQPATGRLDTRPFCSGRGNFSTEGCG--CVCEPGWKGPNCS--EPECPGNCHLR 197
+G C A +++P C G S++G G C C PG +G C P P C
Sbjct: 725 SGPRCSQSLARDACESQP-CRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHG 783
Query: 198 GRC--IDGQ---CICDDGFTGEDCSQ----LACPSDCNDQGKCVNGV----CICFEGYAG 244
GRC GQ C C G+ G C Q A P+ C G C N C C GY G
Sbjct: 784 GRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTG 843
Query: 245 ADCSREI--C-PVPCSEEHGTCVDGL----CVCHDGFAGDDCNKPL--CLNNCYNRGRCV 295
C ++I C P PC G+C DG+ C C GFAG C + + CL+N G C
Sbjct: 844 PSCDQDINDCDPNPCLNG-GSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGTCT 902
Query: 296 EN----ECVCDEGFTGEDCSELI---CPNDCFDRGRCING----TCYCEEGFTGEDC--- 341
++ C C G+ G C + + P+ CF+ G C++G +C C G+TG C
Sbjct: 903 DHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHE 962
Query: 342 GKPTCPHACHTQGRCEEG----QCVCDEGFAGVDCSE-----KRCPADCHNRGRCVD--G 390
P C G C +C C E F G C R P C N GRCV
Sbjct: 963 ADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQP--CQNGGRCVQTGA 1020
Query: 391 RCECDDGFTGADCG--ELKCPNG-----------CSGHGRCVNGQ----CVCDEGYTGED 433
C C G++G C L C C G+CV+ CVC EG TG
Sbjct: 1021 YCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSH 1080
Query: 434 CSQLRCP---NDCHSRGRC---VEG-KCVCEQGFKGYDCSD------------------- 467
C Q P C G C + G C C G+ G +C D
Sbjct: 1081 CEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDL 1140
Query: 468 -----MSCPND------------------------CHQHGRCVNGM----CVCDDGYTG- 493
SCP C +G CV+ + C C GYTG
Sbjct: 1141 VARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGL 1200
Query: 494 ------EDCRDRQC----PRDCSNRGLCVDG---QCVCEDGFTGPDCAELSCPND---CH 537
+CR C RDC L G +C+C GF+GP C + P + C
Sbjct: 1201 RCEADINECRSGACHAAHTRDC----LQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQ 1256
Query: 538 GQGRC---------VNGQCVCHEGFMG-------KDCKEQRCP----------------- 564
G+C + C C + F G + C+E +CP
Sbjct: 1257 HGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCACP 1316
Query: 565 -------------------------SDCHGQGRCVDG------QCICHEGFTGLDCGQHS 593
+ C G C +C C +G+TG C +
Sbjct: 1317 PGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPA 1376
Query: 594 CPSDCNNLGQCVSGRC-----------ICNE---GYSGEDCS 621
+ + +C C CN G+ G DCS
Sbjct: 1377 AAPEVSEEPRCPRAACQAKRGDQRCDRECNSPGCGWDGGDCS 1418
Score = 146 bits (368), Expect = 3e-34
Identities = 164/622 (26%), Positives = 220/622 (35%), Gaps = 149/622 (23%)
Query: 74 EKDLAPPSEPSESFQEHT-VDGENQIVFTHRINIPRRACGCAAAPDVKELLSRLEELENL 132
E+DL P PS F T VDG N R C A P LSR L
Sbjct: 922 EQDL-PDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADP----CLSR----PCL 972
Query: 133 VSSLREQCTAGAGC-CLQPATGR-----LD--TRPFCSGRGNFSTEGCGCVCEPGWKGPN 184
+ G C CL+ TG +D +R C G G C+C PGW G
Sbjct: 973 HGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCPPGWSGRL 1032
Query: 185 CSEPECPGN-------------CHLRGRCIDGQ----CICDDGFTGEDCSQLACP---SD 224
C P C G+C+D C+C +G TG C Q P
Sbjct: 1033 CDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQP 1092
Query: 225 CNDQGKC---VNG-VCICFEGYAGADCSREI--CPVPCSEEHGTCVD----GLCVCHDGF 274
C G C + G +C C GY G +C ++ C + G+C+D LC C G
Sbjct: 1093 CQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGT 1152
Query: 275 AG-------DDCNKPLCLNN---CYNRGRCVE----NECVCDEGFTGEDCSELICPNDCF 320
G DDC L++ C + G CV+ C C G+TG C
Sbjct: 1153 LGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEA-------- 1204
Query: 321 DRGRCINGTCYCEEGFTGEDCGKPTCPHACHTQGRCEEG----QCVCDEGFAGVDCSEKR 376
D C +G C HA HT+ ++ +C+C GF+G C
Sbjct: 1205 DINECRSGAC-----------------HAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVL 1247
Query: 377 CPAD---CHNRGRC---------VDGRCECDDGFTG-------ADCGELKCPNGCSGHGR 417
P + C + G+C + C C F G C EL+CP G
Sbjct: 1248 SPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQT 1307
Query: 418 CVNGQCVCDEGYTGEDC-----SQLRCPNDCHSRGRCVEG------------KCVCEQGF 460
+C C G +G C S N + C+ G +C C QG+
Sbjct: 1308 PRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGW 1367
Query: 461 KGYDCSDMSCPNDCHQHGRCVNGMCVCDDGYTGEDCRDRQCPRDCSNRGLCVD-GQCVCE 519
G C + + + RC C G D++C R+C++ G D G C
Sbjct: 1368 TGPRCEAPAAAPEVSEEPRCPRAACQAKRG-------DQRCDRECNSPGCGWDGGDCSLS 1420
Query: 520 DGFTGPDCAELSC---PNDCHGQGRCVNGQCV-----CHEGFMGKDCK---EQRCPSDCH 568
G C L C N+ C + C+ CH G + C E+ C +D
Sbjct: 1421 VGDPWRQCEALQCWRLFNNSRCDPACSSPACLYDNFDCHAGGRERTCNPVYEKYC-ADHF 1479
Query: 569 GQGRCVDGQCICHE-GFTGLDC 589
GRC G C E G+ GLDC
Sbjct: 1480 ADGRCDQG-CNTEECGWDGLDC 1500
Score = 57.4 bits (137), Expect = 2e-07
Identities = 52/183 (28%), Positives = 64/183 (34%), Gaps = 61/183 (33%)
Query: 474 CHQHGRCVN-----GMCVCDDGYTGEDCR--DRQCPRDCSNRGLCVDG--------QCVC 518
C GRC C+C G+ GE C+ D C+ RG+C C C
Sbjct: 49 CANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRC 108
Query: 519 EDGFTGPDCAELSCPNDC------HGQGRCVNGQ-----CVCHEGFMGKDCK----EQRC 563
GF GPDC S P+ C HG RC G C C G+ G+ C+ E R
Sbjct: 109 PRGFRGPDC---SLPDPCLSSPCAHG-ARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRV 164
Query: 564 PSDCHGQGRCVDGQCICHEGFTGLDCGQHSCPSDCNNLGQCVSGRCICNEGYSGEDCSEV 623
C G C+ N G S RC C GY+G C
Sbjct: 165 GEPCRHGGTCL------------------------NTPG---SFRCQCPAGYTGPLCENP 197
Query: 624 SPP 626
+ P
Sbjct: 198 AVP 200
Score = 57.4 bits (137), Expect = 2e-07
Identities = 73/337 (21%), Positives = 102/337 (30%), Gaps = 119/337 (35%)
Query: 155 LDTRPFCSGRGNFS--TEGCGCVCEPGWKGPNCSEP--EC-PGNCHLRGR--CIDG---- 203
LD+ P C G G C C PG+ G C EC G CH C+
Sbjct: 1170 LDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGG 1229
Query: 204 -QCICDDGFTGEDCSQLACPSD---CNDQGKC---------VNGVCICFEGYAGADCSRE 250
+C+C GF+G C + P + C G+C + C C + + G C R
Sbjct: 1230 FRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERV 1289
Query: 251 I-------CPV--PCSEEHGTCVDGLCVCHDGFAGDDC-----------NKPLCLNNCYN 290
CPV PC + T C C G +G C N C +
Sbjct: 1290 ARSCRELQCPVGVPCQQ---TPRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAAPCLH 1346
Query: 291 RGRCVEN------ECVCDEGFTGEDCSELICPNDCFDRGRCINGTCYCEEG--------- 335
G C C C +G+TG C + + RC C + G
Sbjct: 1347 GGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRCDRECN 1406
Query: 336 -----FTGEDCG-----------------------------KPTCPHA---CHT------ 352
+ G DC P C + CH
Sbjct: 1407 SPGCGWDGGDCSLSVGDPWRQCEALQCWRLFNNSRCDPACSSPACLYDNFDCHAGGRERT 1466
Query: 353 --------------QGRCEEGQCVCDEGFAGVDCSEK 375
GRC++G + G+ G+DC+ +
Sbjct: 1467 CNPVYEKYCADHFADGRCDQGCNTEECGWDGLDCASE 1503
Score = 34.7 bits (78), Expect = 1.1
Identities = 25/78 (32%), Positives = 29/78 (37%), Gaps = 19/78 (24%)
Query: 565 SDCHGQGRCV-----DGQCICHEGFTGLDCGQ----HSCPSDCNNLGQCVSG-------- 607
S C GRC + C+C G+ G C HS P C G C S
Sbjct: 47 SPCANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGP--CAGRGVCQSSVVAGTARF 104
Query: 608 RCICNEGYSGEDCSEVSP 625
C C G+ G DCS P
Sbjct: 105 SCRCPRGFRGPDCSLPDP 122
>gi|122937283 6720455I24Rik homolog [Homo sapiens]
Length = 1413
Score = 213 bits (542), Expect = 2e-54
Identities = 239/906 (26%), Positives = 342/906 (37%), Gaps = 206/906 (22%)
Query: 174 CVCEPGWKGPNC--SEPECPGN-CHLRGRCIDG----QCICDDGFTGEDCSQLACPSD-- 224
C C G+ G C EC C G C G +C C GF G C P D
Sbjct: 297 CSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTK 356
Query: 225 -CNDQGKCV----NGVCICFEGYAGADCSREI---CPVPCSEEHGTCVDGL----CVCHD 272
C G+C + VC+C GY GA C ++ P PC G+CVD + C+C +
Sbjct: 357 ECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPDPCLNG-GSCVDLVGNYTCLCAE 415
Query: 273 GFAGDDCNK------PLCLNN-CYNRGRCVENE----CVCDEGFTGEDCSELICPNDCFD 321
F G C CL+ C+N G CV+ + C C EGF G DC E + P+DC
Sbjct: 416 PFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERV-PDDCEC 474
Query: 322 R--GRCINGT---CYCEEGFTGEDCG----------KPTCPHA-------------CHTQ 353
R GRC+ C C GF G C CP CHT
Sbjct: 475 RNGGRCLGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTD 534
Query: 354 -------------------GRCEEGQ----CVCDEGFAGVDCSEKR----CPADCHNRGR 386
G C+ C C GF G C + R C N G
Sbjct: 535 HNASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGT 594
Query: 387 CVDG----RCECDDGFTGADCGELKCPNGCSGHGRCVNG----------QCVCDEGYTGE 432
C + C C FTG C E+ P+ C+ G C NG +C C G++G
Sbjct: 595 CKEAGGEYHCSCPYRFTGRHC-EIGKPDSCAS-GPCHNGGTCFHYIGKYKCDCPPGFSGR 652
Query: 433 DCSQLRCP---NDCHSRGRCVEGK----CVCEQGFKGYDCS---DMSCPNDCHQHGRCVN 482
C P + C + G C + C C+ G+ G C D P + N
Sbjct: 653 HCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFN 712
Query: 483 G-------MCVCDDGYTG------------------------EDCRDRQCPRDCSNRGLC 511
G + CD GY+ ++CR + C S +
Sbjct: 713 GTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRV 772
Query: 512 VDGQCVCEDGFTGPDCA---ELSCPNDCHGQGRCVNGQ----CVCHEGFMGKDCKEQ--R 562
C+C G+ G C + + C G C N C C GF+G C+ +
Sbjct: 773 AGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDA 832
Query: 563 CPSD-CHGQGRCVDGQ----CICHEGFTGLDCGQHSCP---SDCNNLGQCVSGR----CI 610
C S C GRC G C+C E F G C S P S C G C++ C
Sbjct: 833 CDSSPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCT 892
Query: 611 CNEGYSGEDCS-EVSPPKDLVVTEVTEETVNLAWD--NEMRVTEYLVVYTPTH---EGGL 664
C GY+GEDC+ E+ PP L + V E V+++W+ N + L Y T+ +G
Sbjct: 893 CKVGYTGEDCAKELFPPTALKMERVEESGVSISWNPPNGPAARQMLDGYAVTYVSSDGSY 952
Query: 665 EMQFRVPGDQTSTIIQELEPGVEYFIRVFAILENKKSIPVSARVATYL----PAP-EGLK 719
V ++S +Q L G Y I VF++ N + +R A L P P EG +
Sbjct: 953 RRTDFVDRTRSSHQLQALAAGRAYNISVFSVKRNSNNKNDISRPAVLLARTRPRPVEGFE 1012
Query: 720 FKSIKETSVEVEWDPLDIAFETWEIIFRNMN-----KEDEGEITKSLRRPETSYRQTGLA 774
++ +++ V+W I T + ++ ++ ++ +S+ R + L
Sbjct: 1013 VTNVTASTISVQWALHRIRHATVSGVRVSIRHPEALRDQATDVDRSVDR----FTFRALL 1068
Query: 775 PGQEYEISLHIVKNNTRG---PGLKRVTT-----TRLDAPSQIEVKDVTDTTALITWFKP 826
PG+ Y I L + + RG P T TR P+ + VT T+A + W P
Sbjct: 1069 PGKRYTIQLTTL-SGLRGEEHPTESLATAPTHVWTRPLPPANLTAARVTATSAHVVWDAP 1127
Query: 827 LAEIDGIELTYGIKDVPGDRTTIDLTEDENQ---YSIGNLKPDTEYEVSLI----SRRGD 879
G L + +V ++T + Y++ +L P Y++S+I + G
Sbjct: 1128 ---TPGSLLEAYVINVTTSQSTKSRYVPNGKLASYTVRDLLPGRRYQLSVIAVQSTELGP 1184
Query: 880 MSSNPA 885
S PA
Sbjct: 1185 QHSEPA 1190
Score = 148 bits (374), Expect = 5e-35
Identities = 131/445 (29%), Positives = 165/445 (37%), Gaps = 91/445 (20%)
Query: 273 GFAGDDCNKPLCLNNCYNRGRCVEN--------ECVCDEGFTGEDCS---ELICPNDCFD 321
G G + L L C N G+C+++ C C GFTG C C +
Sbjct: 263 GGCGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQN 322
Query: 322 RGRCING----TCYCEEGFTGEDCGKPTCP---HACHTQGRCE----EGQCVCDEGFAGV 370
G C +G C C GF G C P C G+C+ CVC G+ G
Sbjct: 323 GGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGA 382
Query: 371 DCS---EKRCPADCHNRGRCVD----GRCECDDGFTGADC--GELKCPNG-----CSGHG 416
C + P C N G CVD C C + F G C G+ P+ C G
Sbjct: 383 ACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGG 442
Query: 417 RCVNGQ----CVCDEGYTGEDCSQLRCPNDCHSR--GRCVEGK---CVCEQGFKGYDCSD 467
CV+ C C EG+ G DC + R P+DC R GRC+ C C GF G C
Sbjct: 443 TCVDADQGYVCECPEGFMGLDCRE-RVPDDCECRNGGRCLGANTTLCQCPLGFFGLLCEF 501
Query: 468 MSCPNDCHQHGRCVNG----------MCVCDDGYTGEDCRDRQCPRD-CSNRGLC----V 512
C+ + +C +G +CVC + C D C N G C
Sbjct: 502 EITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGSCDAHDD 561
Query: 513 DGQCVCEDGFTGPDCAELSCPNDCHGQGRCVNG----------QCVCHEGFMGKDC---K 559
C C GF G C E + P+ C G C NG C C F G+ C K
Sbjct: 562 SYTCECPRGFHGKHC-EKARPHLC-SSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGK 619
Query: 560 EQRCPS-DCHGQGRCV----DGQCICHEGFTGLDCGQHSCP---SDCNNLGQC----VSG 607
C S CH G C +C C GF+G C P S C N G C
Sbjct: 620 PDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDF 679
Query: 608 RCICNEGYSGEDCS---EVSPPKDL 629
C C GY G C + PP+++
Sbjct: 680 FCHCQAGYMGRRCQAEVDCGPPEEV 704
Score = 52.4 bits (124), Expect = 5e-06
Identities = 58/269 (21%), Positives = 102/269 (37%), Gaps = 23/269 (8%)
Query: 1713 PKEVIFSDITENSATVSWRAPTA-----QVESFRITYVPITGGTPSMVTVDGTKTQTRLV 1767
P + + E+ ++SW P ++ + +TYV G VD T++ +L
Sbjct: 909 PTALKMERVEESGVSISWNPPNGPAARQMLDGYAVTYVSSDGSYRRTDFVDRTRSSHQLQ 968
Query: 1768 KLIPGVEYLVSIIAMKGFEE-----SEPVSGSFTTALDGPSGLVTANITDSEALARW--- 1819
L G Y +S+ ++K S P T G N+T S +W
Sbjct: 969 ALAAGRAYNISVFSVKRNSNNKNDISRPAVLLARTRPRPVEGFEVTNVTASTISVQWALH 1028
Query: 1820 QPAIATVDSYVISYTG-EKVPEITRTVSGNTVEYALTDLEPATEYTLRIFA------EKG 1872
+ ATV +S E + + V + + L P YT+++ E+
Sbjct: 1029 RIRHATVSGVRVSIRHPEALRDQATDVDRSVDRFTFRALLPGKRYTIQLTTLSGLRGEEH 1088
Query: 1873 PQKS-STITAKFTTDLDSPRDLTATEVQSETALLTWRPPR--ASVTGYLLVYESVDGTVK 1929
P +S +T T P +LTA V + +A + W P + + Y++ + T
Sbjct: 1089 PTESLATAPTHVWTRPLPPANLTAARVTATSAHVVWDAPTPGSLLEAYVINVTTSQSTKS 1148
Query: 1930 EVIVGPDTTSYSLADLSPSTHYTAKIQAL 1958
+ SY++ DL P Y + A+
Sbjct: 1149 RYVPNGKLASYTVRDLLPGRRYQLSVIAV 1177
Score = 46.6 bits (109), Expect = 3e-04
Identities = 67/296 (22%), Positives = 120/296 (40%), Gaps = 46/296 (15%)
Query: 806 PSQIEVKDVTDTTALITWFKPLAE-----IDGIELTYGIKDVPGDRTT-IDLTEDENQYS 859
P+ ++++ V ++ I+W P +DG +TY D RT +D T +Q
Sbjct: 909 PTALKMERVEESGVSISWNPPNGPAARQMLDGYAVTYVSSDGSYRRTDFVDRTRSSHQLQ 968
Query: 860 IGNLKPDTEYEVSLIS--RRGDMSSNPAKETFTTGLDAPRNLRRVSQTD---NSITLEWR 914
L Y +S+ S R + ++ ++ PR + T+ ++I+++W
Sbjct: 969 A--LAAGRAYNISVFSVKRNSNNKNDISRPAVLLARTRPRPVEGFEVTNVTASTISVQWA 1026
Query: 915 NGKAAIDSYRIKYAPISGGD----HAEV------DVPKSQQATTKTTLTGLRPGTEYGIG 964
+RI++A +SG H E DV +S + T L PG Y I
Sbjct: 1027 -------LHRIRHATVSGVRVSIRHPEALRDQATDVDRS---VDRFTFRALLPGKRYTIQ 1076
Query: 965 V---SAVKEDKESNPATINAATELDT----PKDLQVSETAETSLTLLWK--TPLAKFDRY 1015
+ S ++ ++ + A T + T P +L + TS ++W TP + + Y
Sbjct: 1077 LTTLSGLRGEEHPTESLATAPTHVWTRPLPPANLTAARVTATSAHVVWDAPTPGSLLEAY 1136
Query: 1016 RLNYSLPTGQWVGVQLPRNTTSYVLRGLEPGQEYNVLLTA----EKGRHKSKPARV 1067
+N + SY +R L PG+ Y + + A E G S+PA +
Sbjct: 1137 VINVTTSQSTKSRYVPNGKLASYTVRDLLPGRRYQLSVIAVQSTELGPQHSEPAHL 1192
Score = 45.4 bits (106), Expect = 6e-04
Identities = 67/281 (23%), Positives = 113/281 (40%), Gaps = 28/281 (9%)
Query: 1535 LTISDINPYGFTVSWM-----ASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELRGL 1589
L + + G ++SW A+ D + VT V S +F + T+ +L+ L
Sbjct: 912 LKMERVEESGVSISWNPPNGPAARQMLDGYAVTYVSSDGSYRRTDF-VDRTRSSHQLQAL 970
Query: 1590 ITGIGYEVMVSGFTQGHQTK---PLRAEIVTEAEPE-VDNLLVSDATPDGFRLSWTADEG 1645
G Y + V + K A ++ P V+ V++ T + W
Sbjct: 971 AAGRAYNISVFSVKRNSNNKNDISRPAVLLARTRPRPVEGFEVTNVTASTISVQWALHR- 1029
Query: 1646 VFDNFVLKIRDTKKQSEPLEITLLAPERTRD---ITGLREATEYEIELYGIS--KGRRSQ 1700
+ V +R + + E L +R+ D L Y I+L +S +G
Sbjct: 1030 IRHATVSGVRVSIRHPEALRDQATDVDRSVDRFTFRALLPGKRYTIQLTTLSGLRGEEHP 1089
Query: 1701 TVS-AIATTAMGS----PKEVIFSDITENSATVSWRAPT--AQVESFRITYVPITGGTPS 1753
T S A A T + + P + + +T SA V W APT + +E++ I V + T S
Sbjct: 1090 TESLATAPTHVWTRPLPPANLTAARVTATSAHVVWDAPTPGSLLEAYVIN-VTTSQSTKS 1148
Query: 1754 MVTVDGTKTQTRLVKLIPGVEYLVSIIAMK----GFEESEP 1790
+G + L+PG Y +S+IA++ G + SEP
Sbjct: 1149 RYVPNGKLASYTVRDLLPGRRYQLSVIAVQSTELGPQHSEP 1189
Score = 31.6 bits (70), Expect = 9.0
Identities = 20/49 (40%), Positives = 22/49 (44%), Gaps = 9/49 (18%)
Query: 364 DEGFAGVDCSEKRCPADCHNRGRCVDGR----CECDDGFTGADCGELKC 408
D G +CSE C N G CV G C+C GF G C EL C
Sbjct: 1303 DIGNVPGNCSEN----PCQNGGTCVPGADAHSCDCGPGFKGRRC-ELAC 1346
>gi|110347400 odz, odd Oz/ten-m homolog 1 isoform 3 [Homo sapiens]
Length = 2725
Score = 209 bits (531), Expect = 3e-53
Identities = 107/296 (36%), Positives = 146/296 (49%), Gaps = 27/296 (9%)
Query: 189 ECPGNCHLRGRCIDGQCICDDGFTGEDCSQLACPSDCNDQGKCVNGVCICFEGYAGADCS 248
+C NC+ G CI G C C GF G DC++ +CP C G+ G C+C G+ G +C
Sbjct: 531 DCSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECD 590
Query: 249 --REICPVPCSEEHGTCVDGLCVCHDGFAGDDCNKPLCLN-NCYNRGRCVENECVCDEGF 305
E C P HGTC+ G+C+C G+ G+ C + CL+ C N G CV+ EC C G+
Sbjct: 591 VPEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGECHCSTGW 650
Query: 306 TGEDCSE--LICPNDCFDRGRCI--NGTCYCEEGFTGEDCGKPTCPHACHTQGRCEEGQC 361
G +C +C C G + G C C+ +TG DC C C + G C G C
Sbjct: 651 GGVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGIC 710
Query: 362 VCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECDDGFTGADCGELK--------CPNGCS 413
C+EG+ G C E+ C + C G+C DG+CEC G+ G C CP C
Sbjct: 711 QCEEGWVGPTCEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCF 770
Query: 414 GHGRCV---NG-QCVCDEGYTGEDCS---QLRC----PNDCHSRGRCVEGKCVCEQ 458
G+GRC NG CVC G++G C+ ++ C ND CV+ C C+Q
Sbjct: 771 GNGRCTLDQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDC-CQQ 825
Score = 197 bits (500), Expect = 1e-49
Identities = 96/267 (35%), Positives = 129/267 (48%), Gaps = 20/267 (7%)
Query: 377 CPADCHNRGRCVDGRCECDDGFTGADCGELKCPNGCSGHGRCVNGQCVCDEGYTGEDCS- 435
C +C+ G C+ G C C GF G DC CP C G+G G CVC G+ G +C
Sbjct: 532 CSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDV 591
Query: 436 -QLRCPND-CHSRGRCVEGKCVCEQGFKGYDCSDMSCPND-CHQHGRCVNGMCVCDDGYT 492
+ +C + C G C+ G C+C G+KG C + C + C HG CV G C C G+
Sbjct: 592 PEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGECHCSTGWG 651
Query: 493 GEDCRDRQ--CPRDCSNRG--LCVDGQCVCEDGFTGPDCAELSCPNDCHGQGRCVNGQCV 548
G +C C CS G L G C C+ +TG DC+ C +C G C G C
Sbjct: 652 GVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQ 711
Query: 549 CHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTG--------LDCGQHSCPSDCNN 600
C EG++G C+E+ C S C G+C DG+C C G+ G LD + CP C
Sbjct: 712 CEEGWVGPTCEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFG 771
Query: 601 LGQCVSGR----CICNEGYSGEDCSEV 623
G+C + C+C G+SG C+ V
Sbjct: 772 NGRCTLDQNGWHCVCQVGWSGTGCNVV 798
Score = 195 bits (496), Expect = 4e-49
Identities = 112/324 (34%), Positives = 144/324 (44%), Gaps = 32/324 (9%)
Query: 284 CLNNCYNRGRCVENECVCDEGFTGEDCSELICPNDCFDRGRCINGTCYCEEGFTGEDCGK 343
C NC G C+ C C GF G DC+ CP C G G C C G+ G +C
Sbjct: 532 CSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDV 591
Query: 344 PT---CPHACHTQGRCEEGQCVCDEGFAGVDCSEKRC-PADCHNRGRCVDGRCECDDGFT 399
P C G C G C+C G+ G C E+ C C N G CV G C C G+
Sbjct: 592 PEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGECHCSTGWG 651
Query: 400 GADCGELK--CPNGCSGHGRCV--NGQCVCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCV 455
G +C C CSGHG + G C CD +TG DCS C +C S G C G C
Sbjct: 652 GVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQ 711
Query: 456 CEQGFKGYDCSDMSCPNDCHQHGRCVNGMCVCDDGYTGEDC---------RDRQCPRDCS 506
CE+G+ G C + SC + C +HG+C +G C C G+ G+ C RD CP C
Sbjct: 712 CEEGWVGPTCEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRD-GCPGLCF 770
Query: 507 NRGLCVDGQ----CVCEDGFTGPDC---AELSC----PNDCHGQGRCVNGQCVCHEG--F 553
G C Q CVC+ G++G C E+ C ND G CV+ C C + +
Sbjct: 771 GNGRCTLDQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDC-CQQSNCY 829
Query: 554 MGKDCKEQRCPSDCHGQGRCVDGQ 577
+ C+ P D Q + + Q
Sbjct: 830 ISPLCQGSPDPLDLIQQSQTLFSQ 853
Score = 167 bits (424), Expect = 8e-41
Identities = 99/285 (34%), Positives = 128/285 (44%), Gaps = 33/285 (11%)
Query: 139 QCTAGAGCC----LQPATGRLDTRPFCSGRGNFSTEGCGCVCEPGWKGPNCSEPE---CP 191
+C +G C L P R C G G + E CVC GWKGP C PE
Sbjct: 541 ECISGHCHCFPGFLGPDCARDSCPVLCGGNGEY--EKGHCVCRHGWKGPECDVPEEQCID 598
Query: 192 GNCHLRGRCIDGQCICDDGFTGEDCSQLACPSD-CNDQGKCVNGVCICFEGYAGADCSRE 250
C G CI G CIC G+ GE C + C C++ G CV G C C G+ G +C
Sbjct: 599 PTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGECHCSTGWGGVNCETP 658
Query: 251 --ICPVPCSEEHGTCV--DGLCVCHDGFAGDDCNKPLCLNNCYNRGRCVENECVCDEGFT 306
+C CS HGT + G+C C + G DC+ LC C + G C C C+EG+
Sbjct: 659 LPVCQEQCSG-HGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQCEEGWV 717
Query: 307 GEDCSELICPNDCFDRGRCINGTCYCEEGFTGEDCG--------KPTCPHACHTQGRCEE 358
G C E C + C + G+C +G C C G+ G+ C + CP C GRC
Sbjct: 718 GPTCEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTL 777
Query: 359 GQ----CVCDEGFAGVDCS---EKRCPADCHNRGRCVDGRCECDD 396
Q CVC G++G C+ E C + N G DG +C D
Sbjct: 778 DQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDG---DGLTDCVD 819
Score = 141 bits (356), Expect = 6e-33
Identities = 71/194 (36%), Positives = 92/194 (47%), Gaps = 8/194 (4%)
Query: 439 CPNDCHSRGRCVEGKCVCEQGFKGYDCSDMSCPNDCHQHGRCVNGMCVCDDGYTGEDCR- 497
C +C+ G C+ G C C GF G DC+ SCP C +G G CVC G+ G +C
Sbjct: 532 CSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDV 591
Query: 498 -DRQC-PRDCSNRGLCVDGQCVCEDGFTGPDCAELSCPND-CHGQGRCVNGQCVCHEGFM 554
+ QC C G C+ G C+C G+ G C E C + C G CV G+C C G+
Sbjct: 592 PEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGECHCSTGWG 651
Query: 555 GKDCKEQR--CPSDCHGQGRCV--DGQCICHEGFTGLDCGQHSCPSDCNNLGQCVSGRCI 610
G +C+ C C G G + G C C +TG DC C +C + G C G C
Sbjct: 652 GVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQ 711
Query: 611 CNEGYSGEDCSEVS 624
C EG+ G C E S
Sbjct: 712 CEEGWVGPTCEERS 725
Score = 116 bits (291), Expect = 2e-25
Identities = 53/129 (41%), Positives = 66/129 (51%), Gaps = 4/129 (3%)
Query: 501 CPRDCSNRGLCVDGQCVCEDGFTGPDCAELSCPNDCHGQGRCVNGQCVCHEGFMGKDC-- 558
C +C+ G C+ G C C GF GPDCA SCP C G G G CVC G+ G +C
Sbjct: 532 CSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDV 591
Query: 559 -KEQRCPSDCHGQGRCVDGQCICHEGFTGLDCGQHSCPSD-CNNLGQCVSGRCICNEGYS 616
+EQ C G G C+ G CIC G+ G C + C C+N G CV G C C+ G+
Sbjct: 592 PEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGECHCSTGWG 651
Query: 617 GEDCSEVSP 625
G +C P
Sbjct: 652 GVNCETPLP 660
Score = 100 bits (250), Expect = 1e-20
Identities = 56/188 (29%), Positives = 78/188 (41%), Gaps = 41/188 (21%)
Query: 161 CSGRGNFSTEGCGCVCEPGWKGPNCSEPECPGNCHLRGRCIDGQCICDDGFTGEDCSQLA 220
CSG G F + C C+P W G +CS C C G C G C C++G+ G C + +
Sbjct: 666 CSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQCEEGWVGPTCEERS 725
Query: 221 CPSDCNDQGKCVNGVCICFEGYAGADCSREICPVPCSEEHGTCVDGLCVCHDGFAGDDCN 280
C S C + G+C +G C C G+ G +H T L DG
Sbjct: 726 CHSHCTEHGQCKDGKCECSPGWEG--------------DHCTIAHYLDAVRDG------- 764
Query: 281 KPLCLNNCYNRGRCVENE----CVCDEGFTGEDCS---ELICPN----------DCFDRG 323
C C+ GRC ++ CVC G++G C+ E++C + DC D
Sbjct: 765 ---CPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPD 821
Query: 324 RCINGTCY 331
C CY
Sbjct: 822 CCQQSNCY 829
Score = 41.6 bits (96), Expect = 0.009
Identities = 15/33 (45%), Positives = 21/33 (63%)
Query: 594 CPSDCNNLGQCVSGRCICNEGYSGEDCSEVSPP 626
C ++CN G+C+SG C C G+ G DC+ S P
Sbjct: 532 CSTNCNGNGECISGHCHCFPGFLGPDCARDSCP 564
>gi|253970446 odz, odd Oz/ten-m homolog 1 isoform 2 [Homo sapiens]
Length = 2731
Score = 209 bits (531), Expect = 3e-53
Identities = 107/296 (36%), Positives = 146/296 (49%), Gaps = 27/296 (9%)
Query: 189 ECPGNCHLRGRCIDGQCICDDGFTGEDCSQLACPSDCNDQGKCVNGVCICFEGYAGADCS 248
+C NC+ G CI G C C GF G DC++ +CP C G+ G C+C G+ G +C
Sbjct: 530 DCSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECD 589
Query: 249 --REICPVPCSEEHGTCVDGLCVCHDGFAGDDCNKPLCLN-NCYNRGRCVENECVCDEGF 305
E C P HGTC+ G+C+C G+ G+ C + CL+ C N G CV+ EC C G+
Sbjct: 590 VPEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGECHCSTGW 649
Query: 306 TGEDCSE--LICPNDCFDRGRCI--NGTCYCEEGFTGEDCGKPTCPHACHTQGRCEEGQC 361
G +C +C C G + G C C+ +TG DC C C + G C G C
Sbjct: 650 GGVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGIC 709
Query: 362 VCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECDDGFTGADCGELK--------CPNGCS 413
C+EG+ G C E+ C + C G+C DG+CEC G+ G C CP C
Sbjct: 710 QCEEGWVGPTCEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCF 769
Query: 414 GHGRCV---NG-QCVCDEGYTGEDCS---QLRC----PNDCHSRGRCVEGKCVCEQ 458
G+GRC NG CVC G++G C+ ++ C ND CV+ C C+Q
Sbjct: 770 GNGRCTLDQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDC-CQQ 824
Score = 197 bits (500), Expect = 1e-49
Identities = 96/267 (35%), Positives = 129/267 (48%), Gaps = 20/267 (7%)
Query: 377 CPADCHNRGRCVDGRCECDDGFTGADCGELKCPNGCSGHGRCVNGQCVCDEGYTGEDCS- 435
C +C+ G C+ G C C GF G DC CP C G+G G CVC G+ G +C
Sbjct: 531 CSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDV 590
Query: 436 -QLRCPND-CHSRGRCVEGKCVCEQGFKGYDCSDMSCPND-CHQHGRCVNGMCVCDDGYT 492
+ +C + C G C+ G C+C G+KG C + C + C HG CV G C C G+
Sbjct: 591 PEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGECHCSTGWG 650
Query: 493 GEDCRDRQ--CPRDCSNRG--LCVDGQCVCEDGFTGPDCAELSCPNDCHGQGRCVNGQCV 548
G +C C CS G L G C C+ +TG DC+ C +C G C G C
Sbjct: 651 GVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQ 710
Query: 549 CHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTG--------LDCGQHSCPSDCNN 600
C EG++G C+E+ C S C G+C DG+C C G+ G LD + CP C
Sbjct: 711 CEEGWVGPTCEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFG 770
Query: 601 LGQCVSGR----CICNEGYSGEDCSEV 623
G+C + C+C G+SG C+ V
Sbjct: 771 NGRCTLDQNGWHCVCQVGWSGTGCNVV 797
Score = 195 bits (496), Expect = 4e-49
Identities = 112/324 (34%), Positives = 144/324 (44%), Gaps = 32/324 (9%)
Query: 284 CLNNCYNRGRCVENECVCDEGFTGEDCSELICPNDCFDRGRCINGTCYCEEGFTGEDCGK 343
C NC G C+ C C GF G DC+ CP C G G C C G+ G +C
Sbjct: 531 CSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDV 590
Query: 344 PT---CPHACHTQGRCEEGQCVCDEGFAGVDCSEKRC-PADCHNRGRCVDGRCECDDGFT 399
P C G C G C+C G+ G C E+ C C N G CV G C C G+
Sbjct: 591 PEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGECHCSTGWG 650
Query: 400 GADCGELK--CPNGCSGHGRCV--NGQCVCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCV 455
G +C C CSGHG + G C CD +TG DCS C +C S G C G C
Sbjct: 651 GVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQ 710
Query: 456 CEQGFKGYDCSDMSCPNDCHQHGRCVNGMCVCDDGYTGEDC---------RDRQCPRDCS 506
CE+G+ G C + SC + C +HG+C +G C C G+ G+ C RD CP C
Sbjct: 711 CEEGWVGPTCEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRD-GCPGLCF 769
Query: 507 NRGLCVDGQ----CVCEDGFTGPDC---AELSC----PNDCHGQGRCVNGQCVCHEG--F 553
G C Q CVC+ G++G C E+ C ND G CV+ C C + +
Sbjct: 770 GNGRCTLDQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDC-CQQSNCY 828
Query: 554 MGKDCKEQRCPSDCHGQGRCVDGQ 577
+ C+ P D Q + + Q
Sbjct: 829 ISPLCQGSPDPLDLIQQSQTLFSQ 852
Score = 167 bits (424), Expect = 8e-41
Identities = 99/285 (34%), Positives = 128/285 (44%), Gaps = 33/285 (11%)
Query: 139 QCTAGAGCC----LQPATGRLDTRPFCSGRGNFSTEGCGCVCEPGWKGPNCSEPE---CP 191
+C +G C L P R C G G + E CVC GWKGP C PE
Sbjct: 540 ECISGHCHCFPGFLGPDCARDSCPVLCGGNGEY--EKGHCVCRHGWKGPECDVPEEQCID 597
Query: 192 GNCHLRGRCIDGQCICDDGFTGEDCSQLACPSD-CNDQGKCVNGVCICFEGYAGADCSRE 250
C G CI G CIC G+ GE C + C C++ G CV G C C G+ G +C
Sbjct: 598 PTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGECHCSTGWGGVNCETP 657
Query: 251 --ICPVPCSEEHGTCV--DGLCVCHDGFAGDDCNKPLCLNNCYNRGRCVENECVCDEGFT 306
+C CS HGT + G+C C + G DC+ LC C + G C C C+EG+
Sbjct: 658 LPVCQEQCSG-HGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQCEEGWV 716
Query: 307 GEDCSELICPNDCFDRGRCINGTCYCEEGFTGEDCG--------KPTCPHACHTQGRCEE 358
G C E C + C + G+C +G C C G+ G+ C + CP C GRC
Sbjct: 717 GPTCEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTL 776
Query: 359 GQ----CVCDEGFAGVDCS---EKRCPADCHNRGRCVDGRCECDD 396
Q CVC G++G C+ E C + N G DG +C D
Sbjct: 777 DQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDG---DGLTDCVD 818
Score = 141 bits (356), Expect = 6e-33
Identities = 71/194 (36%), Positives = 92/194 (47%), Gaps = 8/194 (4%)
Query: 439 CPNDCHSRGRCVEGKCVCEQGFKGYDCSDMSCPNDCHQHGRCVNGMCVCDDGYTGEDCR- 497
C +C+ G C+ G C C GF G DC+ SCP C +G G CVC G+ G +C
Sbjct: 531 CSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDV 590
Query: 498 -DRQC-PRDCSNRGLCVDGQCVCEDGFTGPDCAELSCPND-CHGQGRCVNGQCVCHEGFM 554
+ QC C G C+ G C+C G+ G C E C + C G CV G+C C G+
Sbjct: 591 PEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGECHCSTGWG 650
Query: 555 GKDCKEQR--CPSDCHGQGRCV--DGQCICHEGFTGLDCGQHSCPSDCNNLGQCVSGRCI 610
G +C+ C C G G + G C C +TG DC C +C + G C G C
Sbjct: 651 GVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQ 710
Query: 611 CNEGYSGEDCSEVS 624
C EG+ G C E S
Sbjct: 711 CEEGWVGPTCEERS 724
Score = 116 bits (291), Expect = 2e-25
Identities = 53/129 (41%), Positives = 66/129 (51%), Gaps = 4/129 (3%)
Query: 501 CPRDCSNRGLCVDGQCVCEDGFTGPDCAELSCPNDCHGQGRCVNGQCVCHEGFMGKDC-- 558
C +C+ G C+ G C C GF GPDCA SCP C G G G CVC G+ G +C
Sbjct: 531 CSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDV 590
Query: 559 -KEQRCPSDCHGQGRCVDGQCICHEGFTGLDCGQHSCPSD-CNNLGQCVSGRCICNEGYS 616
+EQ C G G C+ G CIC G+ G C + C C+N G CV G C C+ G+
Sbjct: 591 PEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGECHCSTGWG 650
Query: 617 GEDCSEVSP 625
G +C P
Sbjct: 651 GVNCETPLP 659
Score = 100 bits (250), Expect = 1e-20
Identities = 56/188 (29%), Positives = 78/188 (41%), Gaps = 41/188 (21%)
Query: 161 CSGRGNFSTEGCGCVCEPGWKGPNCSEPECPGNCHLRGRCIDGQCICDDGFTGEDCSQLA 220
CSG G F + C C+P W G +CS C C G C G C C++G+ G C + +
Sbjct: 665 CSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQCEEGWVGPTCEERS 724
Query: 221 CPSDCNDQGKCVNGVCICFEGYAGADCSREICPVPCSEEHGTCVDGLCVCHDGFAGDDCN 280
C S C + G+C +G C C G+ G +H T L DG
Sbjct: 725 CHSHCTEHGQCKDGKCECSPGWEG--------------DHCTIAHYLDAVRDG------- 763
Query: 281 KPLCLNNCYNRGRCVENE----CVCDEGFTGEDCS---ELICPN----------DCFDRG 323
C C+ GRC ++ CVC G++G C+ E++C + DC D
Sbjct: 764 ---CPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPD 820
Query: 324 RCINGTCY 331
C CY
Sbjct: 821 CCQQSNCY 828
Score = 41.6 bits (96), Expect = 0.009
Identities = 15/33 (45%), Positives = 21/33 (63%)
Query: 594 CPSDCNNLGQCVSGRCICNEGYSGEDCSEVSPP 626
C ++CN G+C+SG C C G+ G DC+ S P
Sbjct: 531 CSTNCNGNGECISGHCHCFPGFLGPDCARDSCP 563
>gi|253970444 odz, odd Oz/ten-m homolog 1 isoform 1 [Homo sapiens]
Length = 2732
Score = 209 bits (531), Expect = 3e-53
Identities = 107/296 (36%), Positives = 146/296 (49%), Gaps = 27/296 (9%)
Query: 189 ECPGNCHLRGRCIDGQCICDDGFTGEDCSQLACPSDCNDQGKCVNGVCICFEGYAGADCS 248
+C NC+ G CI G C C GF G DC++ +CP C G+ G C+C G+ G +C
Sbjct: 531 DCSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECD 590
Query: 249 --REICPVPCSEEHGTCVDGLCVCHDGFAGDDCNKPLCLN-NCYNRGRCVENECVCDEGF 305
E C P HGTC+ G+C+C G+ G+ C + CL+ C N G CV+ EC C G+
Sbjct: 591 VPEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGECHCSTGW 650
Query: 306 TGEDCSE--LICPNDCFDRGRCI--NGTCYCEEGFTGEDCGKPTCPHACHTQGRCEEGQC 361
G +C +C C G + G C C+ +TG DC C C + G C G C
Sbjct: 651 GGVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGIC 710
Query: 362 VCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECDDGFTGADCGELK--------CPNGCS 413
C+EG+ G C E+ C + C G+C DG+CEC G+ G C CP C
Sbjct: 711 QCEEGWVGPTCEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCF 770
Query: 414 GHGRCV---NG-QCVCDEGYTGEDCS---QLRC----PNDCHSRGRCVEGKCVCEQ 458
G+GRC NG CVC G++G C+ ++ C ND CV+ C C+Q
Sbjct: 771 GNGRCTLDQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDC-CQQ 825
Score = 197 bits (500), Expect = 1e-49
Identities = 96/267 (35%), Positives = 129/267 (48%), Gaps = 20/267 (7%)
Query: 377 CPADCHNRGRCVDGRCECDDGFTGADCGELKCPNGCSGHGRCVNGQCVCDEGYTGEDCS- 435
C +C+ G C+ G C C GF G DC CP C G+G G CVC G+ G +C
Sbjct: 532 CSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDV 591
Query: 436 -QLRCPND-CHSRGRCVEGKCVCEQGFKGYDCSDMSCPND-CHQHGRCVNGMCVCDDGYT 492
+ +C + C G C+ G C+C G+KG C + C + C HG CV G C C G+
Sbjct: 592 PEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGECHCSTGWG 651
Query: 493 GEDCRDRQ--CPRDCSNRG--LCVDGQCVCEDGFTGPDCAELSCPNDCHGQGRCVNGQCV 548
G +C C CS G L G C C+ +TG DC+ C +C G C G C
Sbjct: 652 GVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQ 711
Query: 549 CHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTG--------LDCGQHSCPSDCNN 600
C EG++G C+E+ C S C G+C DG+C C G+ G LD + CP C
Sbjct: 712 CEEGWVGPTCEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFG 771
Query: 601 LGQCVSGR----CICNEGYSGEDCSEV 623
G+C + C+C G+SG C+ V
Sbjct: 772 NGRCTLDQNGWHCVCQVGWSGTGCNVV 798
Score = 195 bits (496), Expect = 4e-49
Identities = 112/324 (34%), Positives = 144/324 (44%), Gaps = 32/324 (9%)
Query: 284 CLNNCYNRGRCVENECVCDEGFTGEDCSELICPNDCFDRGRCINGTCYCEEGFTGEDCGK 343
C NC G C+ C C GF G DC+ CP C G G C C G+ G +C
Sbjct: 532 CSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDV 591
Query: 344 PT---CPHACHTQGRCEEGQCVCDEGFAGVDCSEKRC-PADCHNRGRCVDGRCECDDGFT 399
P C G C G C+C G+ G C E+ C C N G CV G C C G+
Sbjct: 592 PEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGECHCSTGWG 651
Query: 400 GADCGELK--CPNGCSGHGRCV--NGQCVCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCV 455
G +C C CSGHG + G C CD +TG DCS C +C S G C G C
Sbjct: 652 GVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQ 711
Query: 456 CEQGFKGYDCSDMSCPNDCHQHGRCVNGMCVCDDGYTGEDC---------RDRQCPRDCS 506
CE+G+ G C + SC + C +HG+C +G C C G+ G+ C RD CP C
Sbjct: 712 CEEGWVGPTCEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRD-GCPGLCF 770
Query: 507 NRGLCVDGQ----CVCEDGFTGPDC---AELSC----PNDCHGQGRCVNGQCVCHEG--F 553
G C Q CVC+ G++G C E+ C ND G CV+ C C + +
Sbjct: 771 GNGRCTLDQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDC-CQQSNCY 829
Query: 554 MGKDCKEQRCPSDCHGQGRCVDGQ 577
+ C+ P D Q + + Q
Sbjct: 830 ISPLCQGSPDPLDLIQQSQTLFSQ 853
Score = 167 bits (424), Expect = 8e-41
Identities = 99/285 (34%), Positives = 128/285 (44%), Gaps = 33/285 (11%)
Query: 139 QCTAGAGCC----LQPATGRLDTRPFCSGRGNFSTEGCGCVCEPGWKGPNCSEPE---CP 191
+C +G C L P R C G G + E CVC GWKGP C PE
Sbjct: 541 ECISGHCHCFPGFLGPDCARDSCPVLCGGNGEY--EKGHCVCRHGWKGPECDVPEEQCID 598
Query: 192 GNCHLRGRCIDGQCICDDGFTGEDCSQLACPSD-CNDQGKCVNGVCICFEGYAGADCSRE 250
C G CI G CIC G+ GE C + C C++ G CV G C C G+ G +C
Sbjct: 599 PTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGECHCSTGWGGVNCETP 658
Query: 251 --ICPVPCSEEHGTCV--DGLCVCHDGFAGDDCNKPLCLNNCYNRGRCVENECVCDEGFT 306
+C CS HGT + G+C C + G DC+ LC C + G C C C+EG+
Sbjct: 659 LPVCQEQCSG-HGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQCEEGWV 717
Query: 307 GEDCSELICPNDCFDRGRCINGTCYCEEGFTGEDCG--------KPTCPHACHTQGRCEE 358
G C E C + C + G+C +G C C G+ G+ C + CP C GRC
Sbjct: 718 GPTCEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTL 777
Query: 359 GQ----CVCDEGFAGVDCS---EKRCPADCHNRGRCVDGRCECDD 396
Q CVC G++G C+ E C + N G DG +C D
Sbjct: 778 DQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDG---DGLTDCVD 819
Score = 141 bits (356), Expect = 6e-33
Identities = 71/194 (36%), Positives = 92/194 (47%), Gaps = 8/194 (4%)
Query: 439 CPNDCHSRGRCVEGKCVCEQGFKGYDCSDMSCPNDCHQHGRCVNGMCVCDDGYTGEDCR- 497
C +C+ G C+ G C C GF G DC+ SCP C +G G CVC G+ G +C
Sbjct: 532 CSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDV 591
Query: 498 -DRQC-PRDCSNRGLCVDGQCVCEDGFTGPDCAELSCPND-CHGQGRCVNGQCVCHEGFM 554
+ QC C G C+ G C+C G+ G C E C + C G CV G+C C G+
Sbjct: 592 PEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGECHCSTGWG 651
Query: 555 GKDCKEQR--CPSDCHGQGRCV--DGQCICHEGFTGLDCGQHSCPSDCNNLGQCVSGRCI 610
G +C+ C C G G + G C C +TG DC C +C + G C G C
Sbjct: 652 GVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQ 711
Query: 611 CNEGYSGEDCSEVS 624
C EG+ G C E S
Sbjct: 712 CEEGWVGPTCEERS 725
Score = 116 bits (291), Expect = 2e-25
Identities = 53/129 (41%), Positives = 66/129 (51%), Gaps = 4/129 (3%)
Query: 501 CPRDCSNRGLCVDGQCVCEDGFTGPDCAELSCPNDCHGQGRCVNGQCVCHEGFMGKDC-- 558
C +C+ G C+ G C C GF GPDCA SCP C G G G CVC G+ G +C
Sbjct: 532 CSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDV 591
Query: 559 -KEQRCPSDCHGQGRCVDGQCICHEGFTGLDCGQHSCPSD-CNNLGQCVSGRCICNEGYS 616
+EQ C G G C+ G CIC G+ G C + C C+N G CV G C C+ G+
Sbjct: 592 PEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGECHCSTGWG 651
Query: 617 GEDCSEVSP 625
G +C P
Sbjct: 652 GVNCETPLP 660
Score = 100 bits (250), Expect = 1e-20
Identities = 56/188 (29%), Positives = 78/188 (41%), Gaps = 41/188 (21%)
Query: 161 CSGRGNFSTEGCGCVCEPGWKGPNCSEPECPGNCHLRGRCIDGQCICDDGFTGEDCSQLA 220
CSG G F + C C+P W G +CS C C G C G C C++G+ G C + +
Sbjct: 666 CSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQCEEGWVGPTCEERS 725
Query: 221 CPSDCNDQGKCVNGVCICFEGYAGADCSREICPVPCSEEHGTCVDGLCVCHDGFAGDDCN 280
C S C + G+C +G C C G+ G +H T L DG
Sbjct: 726 CHSHCTEHGQCKDGKCECSPGWEG--------------DHCTIAHYLDAVRDG------- 764
Query: 281 KPLCLNNCYNRGRCVENE----CVCDEGFTGEDCS---ELICPN----------DCFDRG 323
C C+ GRC ++ CVC G++G C+ E++C + DC D
Sbjct: 765 ---CPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPD 821
Query: 324 RCINGTCY 331
C CY
Sbjct: 822 CCQQSNCY 829
Score = 41.6 bits (96), Expect = 0.009
Identities = 15/33 (45%), Positives = 21/33 (63%)
Query: 594 CPSDCNNLGQCVSGRCICNEGYSGEDCSEVSPP 626
C ++CN G+C+SG C C G+ G DC+ S P
Sbjct: 532 CSTNCNGNGECISGHCHCFPGFLGPDCARDSCP 564
>gi|93141049 collagen, type XII, alpha 1 short isoform precursor [Homo
sapiens]
Length = 1899
Score = 202 bits (515), Expect = 2e-51
Identities = 221/960 (23%), Positives = 392/960 (40%), Gaps = 79/960 (8%)
Query: 610 ICNEGYSGEDCSEVSPPKDLVVTEVTEETVNLAWDNEM-RVTEYLVVYTPTHEGGLEMQF 668
+CN S + ++ P +LV++E T + ++W V Y V Y P GG +F
Sbjct: 211 LCN---SVKGPGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPV-SGGKRQEF 266
Query: 669 RVPGDQTSTIIQELEPGVEYFIRVFAILENKKSIPVSARVATYLPAP-EGLKFKSIKETS 727
V +TST++++L+P EY + V++++E++ S P+ T LP P L + T+
Sbjct: 267 YVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKT-LPVPVVSLNIYDVGPTT 325
Query: 728 VEVEWDPLDIAFETWEIIFRNMNKEDEGEITKSLRRPET--SYRQTGLAPGQEYEISLHI 785
+ V+W P+ A T I+ K+ E K +R T + T L P EY +++
Sbjct: 326 MHVQWQPVGGA--TGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQA 383
Query: 786 VKNN-TRGPGLKRVTTTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPG 844
V ++ T P R T L P ++++DVT +T + W ++ + Y K
Sbjct: 384 VLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRY--KTPEE 441
Query: 845 DRTTIDLTEDENQYSIGNLKPDTEYEVSLISRRGDMSSNP--AKETFTTGLDAPRNLRRV 902
D +++ E S+ +L T Y VS+ + + S P A+ET T + AP NL+
Sbjct: 442 DVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQET-TRPVPAPTNLKIT 500
Query: 903 SQTDNSITLEWRNGKAAIDSYRIKYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYG 962
T W +G + + YRI +AP D E + + L P T Y
Sbjct: 501 EVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETILNGDENT---LVFENLNPNTIYE 557
Query: 963 IGVSAVKEDKESNPATINAATEL---------DTPKDLQVSETAETSLTLLWKTPLAKFD 1013
+ ++A+ D+ + I + L P++LQV SLT+ W +
Sbjct: 558 VSITAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQ 617
Query: 1014 RYRLNYSLPTGQW--VGVQLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKAST 1071
+YR+ Y TG+ + S VL+ L+P Y + +++ + + T
Sbjct: 618 KYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKT 677
Query: 1072 EQAPELENLTVTEVGWDGLRLNWTAAD-QAYEHFIIQVQEANKVEAARNLTVPGSLRAVD 1130
+ + NL V + L + W A+ ++ + A E + +PG+
Sbjct: 678 KPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEEL--VPIPGNTNYAI 735
Query: 1131 IPGLKAATPYTVSIYGVI---QGYRTPVLSAEASTGETPNLG---EVVVAEVGWDALKLN 1184
+ L+ T YTV++ V G RT + TG T G V V ++L +
Sbjct: 736 LRNLQPDTSYTVTVVPVYTEGDGGRT------SDTGRTLMRGLARNVQVYNPTPNSLDVR 789
Query: 1185 WTAPEGAYEYFFIQVQEADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFST 1244
W G + + D ++++ VPG R L L T Y++ + + D
Sbjct: 790 WDPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEG 849
Query: 1245 TPLSVEVLTEEVPDMGNLTVTEVSWDALRLNWTTPDGTYDQFTI--QVQEADQVEEAHNL 1302
P + T NL V + ++L + W DG Q+ I D ++E
Sbjct: 850 NPSPAQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDE--YT 907
Query: 1303 TVPGSLRSMEIPGLRAGTPYTVTLHGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWDG 1362
TVPG ++ + L+ TPY +T+ L T L ++ +S+ +
Sbjct: 908 TVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTR 967
Query: 1363 LRLNWTAADNAYEHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIR 1422
R++W + + + I + V E + G + + + L +T Y V++Y
Sbjct: 968 FRVSWDPSPSPVLGYKIVYKPVGSNEPME--AFVGEMTSYTLHNLNPSTTYDVNVYAQYD 1025
Query: 1423 GYRTPVLSAEASTAKEPEIGNLNVSDITPESFNLSWMATDGIFETFTIE-----IIDSNR 1477
+ L+ + +T LNV+D+ +++ + W +TF ++ S R
Sbjct: 1026 SGLSVPLTDQGTTL------YLNVTDL--KTYQIGW-------DTFCVKWSPHRAATSYR 1070
Query: 1478 L-------LETVEYNISGAERTAHISGLPPSTDFIVYLSGLAPSIRTKTISATATTEALP 1530
L E + G+E + +GL P TD+ V + P++ +S T P
Sbjct: 1071 LKLSPADGTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKP 1130
Score = 172 bits (437), Expect = 2e-42
Identities = 219/927 (23%), Positives = 365/927 (39%), Gaps = 53/927 (5%)
Query: 788 NNTRGPGLKRVTTTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRT 847
N+ +GPG L+APS + + + T + ++W P +D ++ Y G R
Sbjct: 213 NSVKGPG-------DLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEY-YPVSGGKRQ 264
Query: 848 TIDLTEDENQYSIGNLKPDTEYEVSLISRRGDMSSNPAKETFTTGLDAP---RNLRRVSQ 904
++ E + +LKP+TEY V++ S D S P K T T L P N+ V
Sbjct: 265 EFYVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKT-LPVPVVSLNIYDVGP 323
Query: 905 TDNSITLEWRNGKAAIDSYRIKYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIG 964
T ++ ++W+ A Y + Y P+ + + LT L P TEY +
Sbjct: 324 T--TMHVQWQPVGGAT-GYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVT 380
Query: 965 VSAVKEDKESNPATINAAT-ELDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYSLPT 1023
V AV D S P T+ T L P+DL++ + +++ + W+ K +Y + Y P
Sbjct: 381 VQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPE 440
Query: 1024 GQWVGVQLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTEQAPELENLTVT 1083
V++ R+ TS L+ L Y V ++A +S P + +T P NL +T
Sbjct: 441 EDVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKIT 500
Query: 1084 EVGWDGLRLNWT--AAD-QAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPY 1140
EV +G R W A+D Y ++K+E N G + L T Y
Sbjct: 501 EVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETILN----GDENTLVFENLNPNTIY 556
Query: 1141 TVSIYGV----------IQGYRT-PVLSAEASTGETPNLGEVVVAEVGWDALKLNWTAPE 1189
VSI + I RT P+L+ +A NL V ++L + W
Sbjct: 557 EVSITAIYPDESESDDLIGSERTLPILTTQAPKSGPRNL---QVYNATSNSLTVKWDPAS 613
Query: 1190 GAYEYFFIQVQEADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSV 1249
G + + I Q + Q T+ G S L LK T YTIT+ + D ++
Sbjct: 614 GRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTG 673
Query: 1250 EVLTEEVPDMGNLTVTEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLR 1309
T+ + + NL V + S L + W +G Q+ + A E + +PG+
Sbjct: 674 RGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPE-ELVPIPGNTN 732
Query: 1310 SMEIPGLRAGTPYTVT---LHGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWDGLRLN 1366
+ L+ T YTVT ++ E G T + L + ++ V + L +
Sbjct: 733 YAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTG-RTLMRGLAR--NVQVYNPTPNSLDVR 789
Query: 1367 WTAADNAYEHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRT 1426
W A + + V+ ++++ +PG+ R V + L T Y V++ +
Sbjct: 790 WDPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEG 849
Query: 1427 PVLSAEASTAKEPEIGNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETV-EY- 1484
A+ T NL V T S +++W DG + + II S + + + EY
Sbjct: 850 NPSPAQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQY--RIIYSPTVGDPIDEYT 907
Query: 1485 NISGAERTAHISGLPPSTDFIVYLSGLAPSIRTKTISATATTEALPLLENLTISDINPYG 1544
+ G + L P T + + + + ++ T L +N+ ISD
Sbjct: 908 TVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTR 967
Query: 1545 FTVSWMASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFTQ 1604
F VSW S + + + G +P E G L L Y+V V
Sbjct: 968 FRVSWDPSPSPVLGYKIVYKPVGS-NEPME-AFVGEMTSYTLHNLNPSTTYDVNVYAQYD 1025
Query: 1605 GHQTKPLRAEIVTEAEPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQSEPL 1664
+ PL + T V +L D F + W+ ++ LK+ +
Sbjct: 1026 SGLSVPL-TDQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRAA-TSYRLKL-SPADGTRGQ 1082
Query: 1665 EITLLAPERTRDITGLREATEYEIELY 1691
EIT+ E + TGL T+Y + ++
Sbjct: 1083 EITVRGSETSHCFTGLSPDTDYGVTVF 1109
Score = 169 bits (428), Expect = 3e-41
Identities = 203/911 (22%), Positives = 358/911 (39%), Gaps = 46/911 (5%)
Query: 1079 NLTVTEVGWDGLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAAT 1138
NL ++E R++WT + + + ++ + + + V + + LK T
Sbjct: 226 NLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKR-QEFYVSRMETSTVLKDLKPET 284
Query: 1139 PYTVSIYGVIQGYRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQ 1198
Y V++Y V++ + L T P + + + +VG + + W GA Y
Sbjct: 285 EYVVNVYSVVEDEYSEPLKGTEKTLPVPVVS-LNIYDVGPTTMHVQWQPVGGATGYILSY 343
Query: 1199 VQEADTVEAA-QNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLTEEVP 1257
DT + + + + L L T Y +T++ V D ++ P++V +T +P
Sbjct: 344 KPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLP 403
Query: 1258 DMGNLTVTEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLR 1317
+L + +V+ + + W G ++ ++ + + E+ + V S S + L
Sbjct: 404 RPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPE--EDVKEVEVDRSETSTSLKDLF 461
Query: 1318 AGTPYTVTLHGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWDGLRLNWTAADNAYEHF 1377
+ T YTV++ + P+ + T +P +L ++EV +G R W + +
Sbjct: 462 SQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLY 521
Query: 1378 VIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGV----------IRGYRT- 1426
I + + + L G + L T Y VSI + I RT
Sbjct: 522 RITWAPFGSSDKMETI-LNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTL 580
Query: 1427 PVLSAEASTAKEPEIG--NLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEY 1484
P+L+ +A P+ G NL V + T S + W G + + I S
Sbjct: 581 PILTTQA-----PKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTT 635
Query: 1485 NISGAERTAHISGLPPSTDFIVYLSGLAPSIRTKTISATATTEALPLLENLTISDINPYG 1544
I G + + + L P T + + +S L P ++ T+ L + NL + D +
Sbjct: 636 TIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTST 695
Query: 1545 FTVSWMASENAFDSFLVTVVDSGKLLDPQEFT-LSGTQRKLELRGLITGIGYEV-MVSGF 1602
V W +E + + + P+E + G LR L Y V +V +
Sbjct: 696 LNVRWDHAEGNPRQYKLFYAPAAG--GPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVY 753
Query: 1603 TQGHQTKPLRAEIVTEAEPEVDNLLVSDATPDGFRLSWTADEGVFDNF--VLKIRDTKKQ 1660
T+G + T N+ V + TP+ + W G + V D +
Sbjct: 754 TEGDGGRTSDTGR-TLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRP 812
Query: 1661 SEPLEITLLAPERTR--DITGLREATEYEIELYGI-SKGRRSQTVSAIATTAMGSPKEVI 1717
SE +++ P TR + L T Y + L + S G + + + T P+ +
Sbjct: 813 SE----SIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRNLR 868
Query: 1718 FSDITENSATVSWRAPTAQVESFRITYVPITGGT-PSMVTVDGTKTQTRLVKLIPGVEYL 1776
T NS +V+W V+ +RI Y P G TV G + L L P Y
Sbjct: 869 VFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYK 928
Query: 1777 VSIIAMKGFEESEPVSGSF-TTALDGPSGLVTANITDSEALARWQPAIATVDSYVISYTG 1835
+++IA+ + ++G+ T L P + ++ + W P+ + V Y I Y
Sbjct: 929 ITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKP 988
Query: 1836 EKVPEITRTVSGNTVEYALTDLEPATEYTLRIFAEKGPQKSSTITAKFTTDLDSPRDLTA 1895
E G Y L +L P+T Y + ++A+ S +T + TT + DL
Sbjct: 989 VGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKT 1048
Query: 1896 TEVQSETALLTWRPPRASVTGYLLVYESVDGT-VKEVIVGPDTTSYSLADLSPSTHY--T 1952
++ +T + W P RA+ T Y L DGT +E+ V TS+ LSP T Y T
Sbjct: 1049 YQIGWDTFCVKWSPHRAA-TSYRLKLSPADGTRGQEITVRGSETSHCFTGLSPDTDYGVT 1107
Query: 1953 AKIQA--LNGP 1961
+Q L GP
Sbjct: 1108 VFVQTPNLEGP 1118
Score = 165 bits (418), Expect = 4e-40
Identities = 213/985 (21%), Positives = 385/985 (39%), Gaps = 48/985 (4%)
Query: 831 DGIEL-TYGIKDVPGDRTTIDLTE--DENQYSIGNLKPDTEYEVSLISRRGDMSSNPAKE 887
+G+EL GIK+ + T+ D + Y++ + + SL D++ N
Sbjct: 162 EGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFE-------SLSRIVDDLTINLCNS 214
Query: 888 TFTTG-LDAPRNLRRVSQTDNSITLEWRNGKAAIDSYRIKYAPISGGDHAEVDVPKSQQA 946
G L+AP NL +T S + W ++D Y+++Y P+SGG E V + +
Sbjct: 215 VKGPGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRME-- 272
Query: 947 TTKTTLTGLRPGTEYGIGVSAVKEDKESNPATINAATELDTPKDLQVSETAETSLTLLWK 1006
T T L L+P TEY + V +V ED+ S P T L + + T++ + W+
Sbjct: 273 -TSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQ 331
Query: 1007 TPLAKFDRYRLNY-----SLPTGQWVGVQLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHK 1061
P+ Y L+Y + PT V+L L L P EY V + A
Sbjct: 332 -PVGGATGYILSYKPVKDTEPTRP-KEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLT 389
Query: 1062 SKPARVKASTEQAPELENLTVTEVGWDGLRLNWTAADQAYEHFIIQVQEANKVEAARNLT 1121
S+P V+ T P ++L + +V + + W +I++ + E + +
Sbjct: 390 SEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPE--EDVKEVE 447
Query: 1122 VPGSLRAVDIPGLKAATPYTVSIYGVIQGYRTPVLSAEASTGETPNLGEVVVAEVGWDAL 1181
V S + + L + T YTVS+ V +P ++A+ +T P + + EV +
Sbjct: 448 VDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGF 507
Query: 1182 KLNWTAPEGAYEYFFIQVQEADTVEAAQNLTVPGGLRSTDL-PGLKAATHYTITIRGVTQ 1240
+ W GA + ++ A + + T+ G +T + L T Y ++I +
Sbjct: 508 RGTWD--HGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYP 565
Query: 1241 DFSTTP------LSVEVLTEEVPDMG--NLTVTEVSWDALRLNWTTPDGTYDQFTIQVQE 1292
D S + ++ +LT + P G NL V + ++L + W G ++ I Q
Sbjct: 566 DESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQP 625
Query: 1293 ADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTVTLHGEVRGHSTRPLAVEVVTEDLPQLGD 1352
+ T+ G S+ + L+ TPYT+T+ + T+ L + +
Sbjct: 626 STGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRN 685
Query: 1353 LAVSEVGWDGLRLNWTAAD-NAYEHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAAT 1411
L V + L + W A+ N ++ + E + + +PG+ + L+ T
Sbjct: 686 LRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPE--ELVPIPGNTNYAILRNLQPDT 743
Query: 1412 PYRVSIYGVIRGYRTPVLSAEASTAKEPEIGNLNVSDITPESFNLSWMATDGIFETFTIE 1471
Y V++ V S T N+ V + TP S ++ W G + +
Sbjct: 744 SYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVV 803
Query: 1472 I--IDSNRLLETVEYNISGAERTAHISGLPPSTDFIVYLSGLAPSIRTKTISATATTEAL 1529
+D R E++ + G R H+ L P T + V L L A T
Sbjct: 804 YSPVDGTRPSESIV--VPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPR 861
Query: 1530 PLLENLTISDINPYGFTVSWMASENAFDSFLVTVVDSGKLLDP--QEFTLSGTQRKLELR 1587
NL + +V+W ++ + ++ S + DP + T+ G + + L+
Sbjct: 862 SGPRNLRVFGETTNSLSVAWDHADGPVQQY--RIIYSPTVGDPIDEYTTVPGRRNNVILQ 919
Query: 1588 GLITGIGYEVMVSGFTQGHQTKPLRAEIVTEAEPEVDNLLVSDATPDGFRLSWTADEGVF 1647
L Y++ V + L T N+ +SD FR+SW
Sbjct: 920 PLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPV 979
Query: 1648 DNFVLKIRDTKKQSEPLEITLLAPERTRDITGLREATEYEIELYGISKGRRSQTVSAIAT 1707
+ + + +EP+E + + + L +T Y++ +Y S ++ T
Sbjct: 980 LGYKIVYKPVGS-NEPME-AFVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGT 1037
Query: 1708 TAMGSPKEVIFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSMVTVDGTKTQTRLV 1767
T + ++ I ++ V W +P S+R+ P G +TV G++T
Sbjct: 1038 TLYLNVTDLKTYQIGWDTFCVKW-SPHRAATSYRLKLSPADGTRGQEITVRGSETSHCFT 1096
Query: 1768 KLIPGVEYLVSIIAMKGFEESEPVS 1792
L P +Y V++ E VS
Sbjct: 1097 GLSPDTDYGVTVFVQTPNLEGPGVS 1121
Score = 118 bits (296), Expect = 6e-26
Identities = 84/256 (32%), Positives = 126/256 (49%), Gaps = 12/256 (4%)
Query: 1712 SPKEVIFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSMVTVDGTKTQTRLVKLIP 1771
+P ++ S+ T S VSW P+ V+ +++ Y P++GG V +T T L L P
Sbjct: 223 APSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDLKP 282
Query: 1772 GVEYLVSIIAMKGFEESEPVSGSFTTALDGPSGLVTANITD---SEALARWQPAIATVDS 1828
EY+V++ ++ E SEP+ G+ T P +V+ NI D + +WQP +
Sbjct: 283 ETEYVVNVYSVVEDEYSEPLKGTEKTL---PVPVVSLNIYDVGPTTMHVQWQP-VGGATG 338
Query: 1829 YVISYTGEKVPEITRTVS---GNTV-EYALTDLEPATEYTLRIFAEKGPQKSSTITAK-F 1883
Y++SY K E TR G TV + LTDL P TEY + + A S +T +
Sbjct: 339 YILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREV 398
Query: 1884 TTDLDSPRDLTATEVQSETALLTWRPPRASVTGYLLVYESVDGTVKEVIVGPDTTSYSLA 1943
T L P+DL +V T + W P V Y++ Y++ + VKEV V TS SL
Sbjct: 399 TLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLK 458
Query: 1944 DLSPSTHYTAKIQALN 1959
DL T YT + A++
Sbjct: 459 DLFSQTLYTVSVSAVH 474
Score = 70.1 bits (170), Expect = 2e-11
Identities = 58/192 (30%), Positives = 82/192 (42%), Gaps = 12/192 (6%)
Query: 1799 LDGPSGLVTANITDSEALARWQPAIATVDSYVISY---TGEKVPEITRTVSGNTVEYALT 1855
L+ PS LV + T W P +VD Y + Y +G K E VS L
Sbjct: 221 LEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFY--VSRMETSTVLK 278
Query: 1856 DLEPATEYTLRIFAEKGPQKSSTITAKFTTDLDSPRDLTATEVQSETALLTWRPPRASVT 1915
DL+P TEY + +++ + S + T L +V T + W+P T
Sbjct: 279 DLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPV-GGAT 337
Query: 1916 GYLLVYESVDGTV----KEVIVGPDTTSYSLADLSPSTHYTAKIQALNGPLRSNMIQTIF 1971
GY+L Y+ V T KEV +GP L DL P+T Y +QA+ L S +
Sbjct: 338 GYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVRE 397
Query: 1972 TTIGLLYPFPKD 1983
T+ L P P+D
Sbjct: 398 VTLPL--PRPQD 407
Score = 41.2 bits (95), Expect = 0.011
Identities = 24/74 (32%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
Query: 1886 DLDSPRDLTATEVQSETALLTWRPPRASVTGYLLVYESVDGTVK-EVIVGPDTTSYSLAD 1944
DL++P +L +E + ++W PP SV Y + Y V G + E V TS L D
Sbjct: 220 DLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKD 279
Query: 1945 LSPSTHYTAKIQAL 1958
L P T Y + ++
Sbjct: 280 LKPETEYVVNVYSV 293
Score = 32.0 bits (71), Expect = 6.9
Identities = 22/89 (24%), Positives = 36/89 (40%), Gaps = 1/89 (1%)
Query: 628 DLVVTEVTEETVNLAWDNEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTIIQELEPGVE 687
DL ++ +T + W T Y + +P +G + V G +TS L P +
Sbjct: 1045 DLKTYQIGWDTFCVKWSPHRAATSYRLKLSPA-DGTRGQEITVRGSETSHCFTGLSPDTD 1103
Query: 688 YFIRVFAILENKKSIPVSARVATYLPAPE 716
Y + VF N + VS + T + E
Sbjct: 1104 YGVTVFVQTPNLEGPGVSVKEHTTVKPTE 1132
>gi|93141047 collagen, type XII, alpha 1 long isoform precursor [Homo
sapiens]
Length = 3063
Score = 202 bits (515), Expect = 2e-51
Identities = 221/960 (23%), Positives = 392/960 (40%), Gaps = 79/960 (8%)
Query: 610 ICNEGYSGEDCSEVSPPKDLVVTEVTEETVNLAWDNEM-RVTEYLVVYTPTHEGGLEMQF 668
+CN S + ++ P +LV++E T + ++W V Y V Y P GG +F
Sbjct: 1375 LCN---SVKGPGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPV-SGGKRQEF 1430
Query: 669 RVPGDQTSTIIQELEPGVEYFIRVFAILENKKSIPVSARVATYLPAP-EGLKFKSIKETS 727
V +TST++++L+P EY + V++++E++ S P+ T LP P L + T+
Sbjct: 1431 YVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKT-LPVPVVSLNIYDVGPTT 1489
Query: 728 VEVEWDPLDIAFETWEIIFRNMNKEDEGEITKSLRRPET--SYRQTGLAPGQEYEISLHI 785
+ V+W P+ A T I+ K+ E K +R T + T L P EY +++
Sbjct: 1490 MHVQWQPVGGA--TGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQA 1547
Query: 786 VKNN-TRGPGLKRVTTTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPG 844
V ++ T P R T L P ++++DVT +T + W ++ + Y K
Sbjct: 1548 VLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRY--KTPEE 1605
Query: 845 DRTTIDLTEDENQYSIGNLKPDTEYEVSLISRRGDMSSNP--AKETFTTGLDAPRNLRRV 902
D +++ E S+ +L T Y VS+ + + S P A+ET T + AP NL+
Sbjct: 1606 DVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQET-TRPVPAPTNLKIT 1664
Query: 903 SQTDNSITLEWRNGKAAIDSYRIKYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYG 962
T W +G + + YRI +AP D E + + L P T Y
Sbjct: 1665 EVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETILNGDENT---LVFENLNPNTIYE 1721
Query: 963 IGVSAVKEDKESNPATINAATEL---------DTPKDLQVSETAETSLTLLWKTPLAKFD 1013
+ ++A+ D+ + I + L P++LQV SLT+ W +
Sbjct: 1722 VSITAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQ 1781
Query: 1014 RYRLNYSLPTGQW--VGVQLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKAST 1071
+YR+ Y TG+ + S VL+ L+P Y + +++ + + T
Sbjct: 1782 KYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKT 1841
Query: 1072 EQAPELENLTVTEVGWDGLRLNWTAAD-QAYEHFIIQVQEANKVEAARNLTVPGSLRAVD 1130
+ + NL V + L + W A+ ++ + A E + +PG+
Sbjct: 1842 KPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEEL--VPIPGNTNYAI 1899
Query: 1131 IPGLKAATPYTVSIYGVI---QGYRTPVLSAEASTGETPNLG---EVVVAEVGWDALKLN 1184
+ L+ T YTV++ V G RT + TG T G V V ++L +
Sbjct: 1900 LRNLQPDTSYTVTVVPVYTEGDGGRT------SDTGRTLMRGLARNVQVYNPTPNSLDVR 1953
Query: 1185 WTAPEGAYEYFFIQVQEADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFST 1244
W G + + D ++++ VPG R L L T Y++ + + D
Sbjct: 1954 WDPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEG 2013
Query: 1245 TPLSVEVLTEEVPDMGNLTVTEVSWDALRLNWTTPDGTYDQFTI--QVQEADQVEEAHNL 1302
P + T NL V + ++L + W DG Q+ I D ++E
Sbjct: 2014 NPSPAQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDE--YT 2071
Query: 1303 TVPGSLRSMEIPGLRAGTPYTVTLHGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWDG 1362
TVPG ++ + L+ TPY +T+ L T L ++ +S+ +
Sbjct: 2072 TVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTR 2131
Query: 1363 LRLNWTAADNAYEHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIR 1422
R++W + + + I + V E + G + + + L +T Y V++Y
Sbjct: 2132 FRVSWDPSPSPVLGYKIVYKPVGSNEPME--AFVGEMTSYTLHNLNPSTTYDVNVYAQYD 2189
Query: 1423 GYRTPVLSAEASTAKEPEIGNLNVSDITPESFNLSWMATDGIFETFTIE-----IIDSNR 1477
+ L+ + +T LNV+D+ +++ + W +TF ++ S R
Sbjct: 2190 SGLSVPLTDQGTTL------YLNVTDL--KTYQIGW-------DTFCVKWSPHRAATSYR 2234
Query: 1478 L-------LETVEYNISGAERTAHISGLPPSTDFIVYLSGLAPSIRTKTISATATTEALP 1530
L E + G+E + +GL P TD+ V + P++ +S T P
Sbjct: 2235 LKLSPADGTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKP 2294
Score = 194 bits (493), Expect = 8e-49
Identities = 248/1024 (24%), Positives = 415/1024 (40%), Gaps = 72/1024 (7%)
Query: 988 PKDLQVSETAETSLTLLWKTPLAKFDRYRLNYSLPTGQ-WVGVQLPRNTTSYVLRGLEPG 1046
PKDL SE W Y + Y G V V P ++TS VL L+P
Sbjct: 635 PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVVEPASSTSVVLSSLKPE 694
Query: 1047 QEYNVLLTAEKGRHKSKPARVKASTEQAPEL-ENLTVTEVGWDGLRLNWTAADQAYEHFI 1105
Y V +TAE S P + +TE+ NL VT+ D ++ WT A +
Sbjct: 695 TLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYR 754
Query: 1106 IQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYG-VIQGYRTPVLSAEASTGE 1164
I + E+ R +T P + R + L T Y VS+ G TP+ A+
Sbjct: 755 IIYRPVAGGES-REVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPLTGNAATEEV 813
Query: 1165 TPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEADTVEAAQNLTVPGGLRSTDLPG 1224
N ++ V++ +KL+W+ G + + + E Q +TV G +T L G
Sbjct: 814 RGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGET-QEVTVRGDTTNTVLQG 872
Query: 1225 LKAATHYTITIRGVTQDFSTTPLSVEVLT-EEVPDMGNLTVTEVSWDALRLNWTTPDGTY 1283
LK T Y +++ + + L E T EE +L +++ ++ WT+ G
Sbjct: 873 LKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSAPGMV 932
Query: 1284 DQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTVTLHGEVRGHSTRPLAVEVV 1343
+ + + + +P I L+ T Y +++ PL +
Sbjct: 933 RGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLTGDAT 992
Query: 1344 TEDLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQVQEVNKVEAAQNLTLPGSLRAVD 1403
TE L V E + +R+ W A ++ + + + + +P ++ +
Sbjct: 993 TELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMV-AKVPPTVTSTV 1051
Query: 1404 IPGLEAATPYRVS---IYGVIRGYRTPVLSAEASTAKEPEIGNLNVSDITPESFNLSWMA 1460
+ L+ T Y ++ IY + G AS K P NL SD T SF ++W
Sbjct: 1052 LKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPR--NLKTSDPTMSSFRVTWEP 1109
Query: 1461 TDGIFETFTIEII---DSNRLLETVEYNISGAERTAHISGLPPSTDFIVYLSGL------ 1511
G + + + D RL E V + + T + L T + V + G+
Sbjct: 1110 APGEVKGYKVTFHPTGDDRRLGELV---VGPYDNTVVLEELRAGTTYKVNVFGMFDGGES 1166
Query: 1512 APSIRTKTISATATTEALPLL----ENLTISDINPYGFTV-SWMASE------NAFDSFL 1560
+P + + + + TT +P+L E LT ++ + SW +F S +
Sbjct: 1167 SPLVGQEMTTLSDTT-VMPILSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRI 1225
Query: 1561 VTVVDSGKLL----------DPQ-EFTLSGTQRKLELRGLITGIGYEV--MVSGFTQGH- 1606
V V D G DP+ E+ L+ + K L + + Y+ ++G
Sbjct: 1226 VEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFI 1285
Query: 1607 QTKPLRAEIVTEAEPEVDNLLVSDA-TPDGFRL--SWTADEGVFDNFVLKIRDTKKQSEP 1663
+ + R + +L++D + D DEGV + F + I K ++
Sbjct: 1286 RQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGV-ELFAIGI----KNADE 1340
Query: 1664 LEITLLAPERTRDITGLREATEYEIELYGISKGRRSQTVSAIATTAMGSPKEVIFSDITE 1723
+E+ ++A + D T ++E + + S + +P ++ S+ T
Sbjct: 1341 VELKMIATDP--DDTHAYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSNLVISERTH 1398
Query: 1724 NSATVSWRAPTAQVESFRITYVPITGGTPSMVTVDGTKTQTRLVKLIPGVEYLVSIIAMK 1783
S VSW P+ V+ +++ Y P++GG V +T T L L P EY+V++ ++
Sbjct: 1399 RSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDLKPETEYVVNVYSVV 1458
Query: 1784 GFEESEPVSGSFTTALDGPSGLVTANITD---SEALARWQPAIATVDSYVISYTGEKVPE 1840
E SEP+ G+ T P +V+ NI D + +WQP + Y++SY K E
Sbjct: 1459 EDEYSEPLKGTEKTL---PVPVVSLNIYDVGPTTMHVQWQP-VGGATGYILSYKPVKDTE 1514
Query: 1841 ITRTVS---GNTV-EYALTDLEPATEYTLRIFAEKGPQKSSTITAK-FTTDLDSPRDLTA 1895
TR G TV + LTDL P TEY + + A S +T + T L P+DL
Sbjct: 1515 PTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKL 1574
Query: 1896 TEVQSETALLTWRPPRASVTGYLLVYESVDGTVKEVIVGPDTTSYSLADLSPSTHYTAKI 1955
+V T + W P V Y++ Y++ + VKEV V TS SL DL T YT +
Sbjct: 1575 RDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLKDLFSQTLYTVSV 1634
Query: 1956 QALN 1959
A++
Sbjct: 1635 SAVH 1638
Score = 177 bits (448), Expect = 1e-43
Identities = 262/1239 (21%), Positives = 471/1239 (38%), Gaps = 95/1239 (7%)
Query: 616 SGEDCSEVSPPKDLVVTEVTEETVNLAWDNEM-RVTEYLVVYTPTHEGGLEMQFRVPGDQ 674
SG S P++L ++ T + + W+ V Y V + PT + + V
Sbjct: 1080 SGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYD 1139
Query: 675 TSTIIQELEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFKSI-KETSVEVEWD 733
+ +++EL G Y + VF + + +S P+ + T L + S E E D
Sbjct: 1140 NTVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTTVMPILSSGMECLTRAEAD 1199
Query: 734 PLDIAFETWEI-----------IFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEIS 782
+ + +W I I R + D G +R + + Q P E++++
Sbjct: 1200 IVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGP-----KRVQIALAQYSGDPRTEWQLN 1254
Query: 783 LHIVK---------------NNTRGPGLK--RVTTTRLDAPSQIEVKDVTDTTALITWFK 825
H K N G L R R A + + + LIT K
Sbjct: 1255 AHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIG---VLITDGK 1311
Query: 826 PLAEID---------GIEL-TYGIKDVPGDRTTIDLTE--DENQYSIGNLKPDTEYEVSL 873
+++ G+EL GIK+ + T+ D + Y++ + + SL
Sbjct: 1312 SQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFE-------SL 1364
Query: 874 ISRRGDMSSNPAKETFTTG-LDAPRNLRRVSQTDNSITLEWRNGKAAIDSYRIKYAPISG 932
D++ N G L+AP NL +T S + W ++D Y+++Y P+SG
Sbjct: 1365 SRIVDDLTINLCNSVKGPGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSG 1424
Query: 933 GDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKEDKESNPATINAATELDTPKDLQ 992
G E V + + T T L L+P TEY + V +V ED+ S P T L
Sbjct: 1425 GKRQEFYVSRME---TSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLN 1481
Query: 993 VSETAETSLTLLWKTPLAKFDRYRLNY-----SLPTGQWVGVQLPRNTTSYVLRGLEPGQ 1047
+ + T++ + W+ P+ Y L+Y + PT V+L L L P
Sbjct: 1482 IYDVGPTTMHVQWQ-PVGGATGYILSYKPVKDTEPTRP-KEVRLGPTVNDMQLTDLVPNT 1539
Query: 1048 EYNVLLTAEKGRHKSKPARVKASTEQAPELENLTVTEVGWDGLRLNWTAADQAYEHFIIQ 1107
EY V + A S+P V+ T P ++L + +V + + W +I++
Sbjct: 1540 EYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVR 1599
Query: 1108 VQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVIQGYRTPVLSAEASTGETPN 1167
+ E + + V S + + L + T YTVS+ V +P ++A+ +T P
Sbjct: 1600 YKTPE--EDVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPA 1657
Query: 1168 LGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEADTVEAAQNLTVPGGLRSTDL-PGLK 1226
+ + EV + + W GA + ++ A + + T+ G +T + L
Sbjct: 1658 PTNLKITEVTSEGFRGTWD--HGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLN 1715
Query: 1227 AATHYTITIRGVTQDFSTTP------LSVEVLTEEVPDMG--NLTVTEVSWDALRLNWTT 1278
T Y ++I + D S + ++ +LT + P G NL V + ++L + W
Sbjct: 1716 PNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDP 1775
Query: 1279 PDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTVTLHGEVRGHSTRPL 1338
G ++ I Q + T+ G S+ + L+ TPYT+T+ +
Sbjct: 1776 ASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRM 1835
Query: 1339 AVEVVTEDLPQLGDLAVSEVGWDGLRLNWTAAD-NAYEHFVIQVQEVNKVEAAQNLTLPG 1397
T+ L + +L V + L + W A+ N ++ + E + + +PG
Sbjct: 1836 TGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPE--ELVPIPG 1893
Query: 1398 SLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEASTAKEPEIGNLNVSDITPESFNLS 1457
+ + L+ T Y V++ V S T N+ V + TP S ++
Sbjct: 1894 NTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVR 1953
Query: 1458 WMATDGIFETFTIEI--IDSNRLLETVEYNISGAERTAHISGLPPSTDFIVYLSGLAPSI 1515
W G + + +D R E++ + G R H+ L P T + V L L
Sbjct: 1954 WDPAPGPVLQYRVVYSPVDGTRPSESIV--VPGNTRMVHLERLIPDTLYSVNLVALYSDG 2011
Query: 1516 RTKTISATATTEALPLLENLTISDINPYGFTVSWMASENAFDSFLVTVVDSGKLLDP--Q 1573
A T NL + +V+W ++ + ++ S + DP +
Sbjct: 2012 EGNPSPAQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQY--RIIYSPTVGDPIDE 2069
Query: 1574 EFTLSGTQRKLELRGLITGIGYEVMVSGFTQGHQTKPLRAEIVTEAEPEVDNLLVSDATP 1633
T+ G + + L+ L Y++ V + L T N+ +SD
Sbjct: 2070 YTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWY 2129
Query: 1634 DGFRLSWTADEGVFDNFVLKIRDTKKQSEPLEITLLAPERTRDITGLREATEYEIELYGI 1693
FR+SW + + + +EP+E + + + L +T Y++ +Y
Sbjct: 2130 TRFRVSWDPSPSPVLGYKIVYKPVGS-NEPME-AFVGEMTSYTLHNLNPSTTYDVNVYAQ 2187
Query: 1694 SKGRRSQTVSAIATTAMGSPKEVIFSDITENSATVSWRAPTAQVESFRITYVPITGGTPS 1753
S ++ TT + ++ I ++ V W +P S+R+ P G
Sbjct: 2188 YDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCVKW-SPHRAATSYRLKLSPADGTRGQ 2246
Query: 1754 MVTVDGTKTQTRLVKLIPGVEYLVSIIAMKGFEESEPVS 1792
+TV G++T L P +Y V++ E VS
Sbjct: 2247 EITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVS 2285
Score = 169 bits (428), Expect = 3e-41
Identities = 203/911 (22%), Positives = 358/911 (39%), Gaps = 46/911 (5%)
Query: 1079 NLTVTEVGWDGLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAAT 1138
NL ++E R++WT + + + ++ + + + V + + LK T
Sbjct: 1390 NLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKR-QEFYVSRMETSTVLKDLKPET 1448
Query: 1139 PYTVSIYGVIQGYRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQ 1198
Y V++Y V++ + L T P + + + +VG + + W GA Y
Sbjct: 1449 EYVVNVYSVVEDEYSEPLKGTEKTLPVPVVS-LNIYDVGPTTMHVQWQPVGGATGYILSY 1507
Query: 1199 VQEADTVEAA-QNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLTEEVP 1257
DT + + + + L L T Y +T++ V D ++ P++V +T +P
Sbjct: 1508 KPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLP 1567
Query: 1258 DMGNLTVTEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLR 1317
+L + +V+ + + W G ++ ++ + + E+ + V S S + L
Sbjct: 1568 RPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPE--EDVKEVEVDRSETSTSLKDLF 1625
Query: 1318 AGTPYTVTLHGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWDGLRLNWTAADNAYEHF 1377
+ T YTV++ + P+ + T +P +L ++EV +G R W + +
Sbjct: 1626 SQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLY 1685
Query: 1378 VIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGV----------IRGYRT- 1426
I + + + L G + L T Y VSI + I RT
Sbjct: 1686 RITWAPFGSSDKMETI-LNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTL 1744
Query: 1427 PVLSAEASTAKEPEIG--NLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEY 1484
P+L+ +A P+ G NL V + T S + W G + + I S
Sbjct: 1745 PILTTQA-----PKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTT 1799
Query: 1485 NISGAERTAHISGLPPSTDFIVYLSGLAPSIRTKTISATATTEALPLLENLTISDINPYG 1544
I G + + + L P T + + +S L P ++ T+ L + NL + D +
Sbjct: 1800 TIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTST 1859
Query: 1545 FTVSWMASENAFDSFLVTVVDSGKLLDPQEFT-LSGTQRKLELRGLITGIGYEV-MVSGF 1602
V W +E + + + P+E + G LR L Y V +V +
Sbjct: 1860 LNVRWDHAEGNPRQYKLFYAPAAG--GPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVY 1917
Query: 1603 TQGHQTKPLRAEIVTEAEPEVDNLLVSDATPDGFRLSWTADEGVFDNF--VLKIRDTKKQ 1660
T+G + T N+ V + TP+ + W G + V D +
Sbjct: 1918 TEGDGGRTSDTGR-TLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRP 1976
Query: 1661 SEPLEITLLAPERTR--DITGLREATEYEIELYGI-SKGRRSQTVSAIATTAMGSPKEVI 1717
SE +++ P TR + L T Y + L + S G + + + T P+ +
Sbjct: 1977 SE----SIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRNLR 2032
Query: 1718 FSDITENSATVSWRAPTAQVESFRITYVPITGGT-PSMVTVDGTKTQTRLVKLIPGVEYL 1776
T NS +V+W V+ +RI Y P G TV G + L L P Y
Sbjct: 2033 VFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYK 2092
Query: 1777 VSIIAMKGFEESEPVSGSF-TTALDGPSGLVTANITDSEALARWQPAIATVDSYVISYTG 1835
+++IA+ + ++G+ T L P + ++ + W P+ + V Y I Y
Sbjct: 2093 ITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKP 2152
Query: 1836 EKVPEITRTVSGNTVEYALTDLEPATEYTLRIFAEKGPQKSSTITAKFTTDLDSPRDLTA 1895
E G Y L +L P+T Y + ++A+ S +T + TT + DL
Sbjct: 2153 VGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKT 2212
Query: 1896 TEVQSETALLTWRPPRASVTGYLLVYESVDGT-VKEVIVGPDTTSYSLADLSPSTHY--T 1952
++ +T + W P RA+ T Y L DGT +E+ V TS+ LSP T Y T
Sbjct: 2213 YQIGWDTFCVKWSPHRAA-TSYRLKLSPADGTRGQEITVRGSETSHCFTGLSPDTDYGVT 2271
Query: 1953 AKIQA--LNGP 1961
+Q L GP
Sbjct: 2272 VFVQTPNLEGP 2282
Score = 134 bits (336), Expect = 1e-30
Identities = 134/573 (23%), Positives = 229/573 (39%), Gaps = 32/573 (5%)
Query: 806 PSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGD-RTTIDLTEDENQYSIGNLK 864
P + +VT W + +TY K+ GD T+ + +LK
Sbjct: 635 PKDLSFSEVTSYGFKTNWSPAGENVFSYHITY--KEAAGDDEVTVVEPASSTSVVLSSLK 692
Query: 865 PDTEYEVSLISRRGDMSSNP--AKETFTTGLDAPRNLRRVSQTDNSITLEWRNGKAAIDS 922
P+T Y V++ + D S P +ET APRNL+ +T +S + W +
Sbjct: 693 PETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPGRVLR 752
Query: 923 YRIKYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKEDKESNPATINAA 982
YRI Y P++GG+ EV P +Q+ + TL L P T+Y + V P T NAA
Sbjct: 753 YRIIYRPVAGGESREVTTPPNQR---RRTLENLIPDTKYEVSVIPEYFSGPGTPLTGNAA 809
Query: 983 TE--LDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYS-LPTGQWVGVQLPRNTTSYV 1039
TE P+DL+VS+ +++ L W K +Y + Y+ + G+ V + +TT+ V
Sbjct: 810 TEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGETQEVTVRGDTTNTV 869
Query: 1040 LRGLEPGQEYNVLLTAEKGRHKSKPARVKAST-EQAPELENLTVTEVGWDGLRLNWTAAD 1098
L+GL+ G +Y + +TA + +T E+ ++L ++ + WT+A
Sbjct: 870 LQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSAP 929
Query: 1099 QAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVIQGYRTPVLSA 1158
+ + + +P I L+ T Y +S++ L+
Sbjct: 930 GMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLTG 989
Query: 1159 EASTGETPNLGEVVVAEVGWDALKLNW-TAPEGAYEYFFIQVQEADTVEAAQNLTVPGGL 1217
+A+T + + + V E + +++ W AP Y + + VP +
Sbjct: 990 DATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAK--VPPTV 1047
Query: 1218 RSTDLPGLKAATHYTITI-------RGVTQDFSTTPLSVEVLTEEVPDMGNLTVTEVSWD 1270
ST L L+ T Y IT+ G + S T S NL ++ +
Sbjct: 1048 TSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTAS------RFKSPRNLKTSDPTMS 1101
Query: 1271 ALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTVTLHGEV 1330
+ R+ W G + + L V ++ + LRAGT Y V + G
Sbjct: 1102 SFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMF 1161
Query: 1331 RGHSTRPLAVEVVTEDLPQLGDLAVSEVGWDGL 1363
G + PL V +++ L D V + G+
Sbjct: 1162 DGGESSPL----VGQEMTTLSDTTVMPILSSGM 1190
Score = 132 bits (333), Expect = 3e-30
Identities = 138/556 (24%), Positives = 226/556 (40%), Gaps = 31/556 (5%)
Query: 625 PPKDLVVTEVTEETVNLAWDNE-MRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTIIQELE 683
PPKDL +EVT W V Y + Y G E+ P TS ++ L+
Sbjct: 634 PPKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEA-AGDDEVTVVEPASSTSVVLSSLK 692
Query: 684 PGVEYFIRVFAILENKKSIPVSARVAT--YLPAPEGLKFKSIKETSVEVEWDPLDIAFET 741
P Y + V A E+ SIP++ T AP LK S ++ W
Sbjct: 693 PETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPGRVLR 752
Query: 742 WEIIFRNMNKEDEGEITKSLRRPETSYRQT--GLAPGQEYEISLHIVKNNTRGPGL---- 795
+ II+R + + E+T P R+T L P +YE+S ++ GPG
Sbjct: 753 YRIIYRPVAGGESREVT----TPPNQRRRTLENLIPDTKYEVS--VIPEYFSGPGTPLTG 806
Query: 796 KRVTTTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDE 855
T P + V D T +T ++W ++ +TY G+ + + D
Sbjct: 807 NAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTY-TPVAGGETQEVTVRGDT 865
Query: 856 NQYSIGNLKPDTEYEVSLISRRGDMSSNP--AKETFTTGLDAPRNLRRVSQTDNSITLEW 913
+ LK T+Y +S+ + + + + T +P++L TD SI W
Sbjct: 866 TNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYW 925
Query: 914 RNGKAAIDSYRIKYAPI-SGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKEDK 972
+ + YR+ + + D E ++P+ T + L+P T+Y I V A
Sbjct: 926 TSAPGMVRGYRVSWKSLYDDVDTGEKNLPED---AIHTMIENLQPETKYRISVFATYSSG 982
Query: 973 ESNPATINAATEL-DTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNY-SLPTGQWVGVQ 1030
E P T +A TEL K L+V E E ++ + WK K YR+ Y G+ + +
Sbjct: 983 EGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAK 1042
Query: 1031 LPRNTTSYVLRGLEPGQEYN--VLLTAEKGRHKSKP-ARVKASTEQAPELENLTVTEVGW 1087
+P TS VL+ L+P Y+ VL + G K + + AS ++P NL ++
Sbjct: 1043 VPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSP--RNLKTSDPTM 1100
Query: 1088 DGLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGV 1147
R+ W A + + + L V V + L+A T Y V+++G+
Sbjct: 1101 SSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGM 1160
Query: 1148 IQ-GYRTPVLSAEAST 1162
G +P++ E +T
Sbjct: 1161 FDGGESSPLVGQEMTT 1176
Score = 104 bits (260), Expect = 8e-22
Identities = 92/384 (23%), Positives = 163/384 (42%), Gaps = 13/384 (3%)
Query: 626 PKDLVVTEVTEETVNLAWDNEM-RVTEYLVVYTPTHEGGLEMQFRVPGDQTSTIIQELEP 684
P+DL V++ T T+ L+W +V +YLV YTP GG + V GD T+T++Q L+
Sbjct: 817 PRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPV-AGGETQEVTVRGDTTNTVLQGLKE 875
Query: 685 GVEYFIRVFAILENKKSIPVSARVATY--LPAPEGLKFKSIKETSVEVEWDPLDIAFETW 742
G +Y + V A+ + + T +P+ L K I +TS+ W +
Sbjct: 876 GTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSAPGMVRGY 935
Query: 743 EIIFRNMNKE-DEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNNTRGPGLKRVTTT 801
+ ++++ + D GE K+L L P +Y IS+ ++ G L TT
Sbjct: 936 RVSWKSLYDDVDTGE--KNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLTGDATT 993
Query: 802 RLDAPSQ-IEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQYSI 860
L S+ ++V + T+ T +TW ++ + Y G + + +
Sbjct: 994 ELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYR-PHGRGKQMVAKVPPTVTSTVL 1052
Query: 861 GNLKPDTEYEVSL--ISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSITLEWRNGKA 918
L+P T Y++++ I + G+ T + +PRNL+ T +S + W
Sbjct: 1053 KRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPG 1112
Query: 919 AIDSYRIKYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKEDKESNPAT 978
+ Y++ + P +G D ++ T L LR GT Y + V + + ES+P
Sbjct: 1113 EVKGYKVTFHP-TGDDRRLGELVVGPYDNT-VVLEELRAGTTYKVNVFGMFDGGESSPLV 1170
Query: 979 INAATELDTPKDLQVSETAETSLT 1002
T L + + + LT
Sbjct: 1171 GQEMTTLSDTTVMPILSSGMECLT 1194
Score = 87.0 bits (214), Expect = 2e-16
Identities = 83/271 (30%), Positives = 112/271 (41%), Gaps = 12/271 (4%)
Query: 1697 RRSQTVSAIATTAMGSPKEVIFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSMVT 1756
R Q ++AI A PK++ FS++T +W V S+ ITY G V
Sbjct: 619 RIEQELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVV 678
Query: 1757 VDGTKTQTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTT--ALDGPSGL-VTANITDS 1813
+ T L L P YLV++ A S P++G TT P L VT TDS
Sbjct: 679 EPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDS 738
Query: 1814 EALARWQPAIATVDSYVISY---TGEKVPEITRTVSGNTVEYALTDLEPATEYTLRIFAE 1870
+ W A V Y I Y G + E+ T N L +L P T+Y + + E
Sbjct: 739 FKIT-WTQAPGRVLRYRIIYRPVAGGESREV--TTPPNQRRRTLENLIPDTKYEVSVIPE 795
Query: 1871 --KGPQKSSTITAKFTTDLDSPRDLTATEVQSETALLTWRPPRASVTGYLLVYESV-DGT 1927
GP T A +PRDL ++ + T L+W V YL+ Y V G
Sbjct: 796 YFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGE 855
Query: 1928 VKEVIVGPDTTSYSLADLSPSTHYTAKIQAL 1958
+EV V DTT+ L L T Y + AL
Sbjct: 856 TQEVTVRGDTTNTVLQGLKEGTQYALSVTAL 886
Score = 70.1 bits (170), Expect = 2e-11
Identities = 58/192 (30%), Positives = 82/192 (42%), Gaps = 12/192 (6%)
Query: 1799 LDGPSGLVTANITDSEALARWQPAIATVDSYVISY---TGEKVPEITRTVSGNTVEYALT 1855
L+ PS LV + T W P +VD Y + Y +G K E VS L
Sbjct: 1385 LEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFY--VSRMETSTVLK 1442
Query: 1856 DLEPATEYTLRIFAEKGPQKSSTITAKFTTDLDSPRDLTATEVQSETALLTWRPPRASVT 1915
DL+P TEY + +++ + S + T L +V T + W+P T
Sbjct: 1443 DLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPV-GGAT 1501
Query: 1916 GYLLVYESVDGTV----KEVIVGPDTTSYSLADLSPSTHYTAKIQALNGPLRSNMIQTIF 1971
GY+L Y+ V T KEV +GP L DL P+T Y +QA+ L S +
Sbjct: 1502 GYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVRE 1561
Query: 1972 TTIGLLYPFPKD 1983
T+ L P P+D
Sbjct: 1562 VTLPL--PRPQD 1571
Score = 63.5 bits (153), Expect = 2e-09
Identities = 61/276 (22%), Positives = 115/276 (41%), Gaps = 14/276 (5%)
Query: 617 GEDCSEVSPPKDLVVTEVTEETVNLAWDNEM-RVTEYLVVYTPTHEGGLEMQFRVPGDQT 675
G E P+DLV ++T+ ++ W + V Y V + ++ + +P D
Sbjct: 899 GTTLEERGSPQDLVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAI 958
Query: 676 STIIQELEPGVEYFIRVFAILENKKSIPVSARVATYLPA-PEGLKFKSIKETSVEVEWDP 734
T+I+ L+P +Y I VFA + + P++ T L + LK E ++ V W P
Sbjct: 959 HTMIENLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKP 1018
Query: 735 LDIAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNNTRGPG 794
+ +++R + ++ + TS L P Y+I+ ++ G G
Sbjct: 1019 APGKVVNYRVVYRPHGRGK--QMVAKVPPTVTSTVLKRLQPQTTYDIT--VLPIYKMGEG 1074
Query: 795 LKR----VTTTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTID 850
R T +R +P ++ D T ++ +TW E+ G ++T+ DR +
Sbjct: 1075 KLRQGSGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTF--HPTGDDRRLGE 1132
Query: 851 LTED--ENQYSIGNLKPDTEYEVSLISRRGDMSSNP 884
L +N + L+ T Y+V++ S+P
Sbjct: 1133 LVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGESSP 1168
Score = 60.8 bits (146), Expect = 1e-08
Identities = 31/84 (36%), Positives = 45/84 (53%)
Query: 1713 PKEVIFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSMVTVDGTKTQTRLVKLIPG 1772
P ++ F I EN+ +SW P + +RIT P T G T+ + T+T L +L+P
Sbjct: 28 PSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSASTTETLLSELVPE 87
Query: 1773 VEYLVSIIAMKGFEESEPVSGSFT 1796
EY+V+I + EES PV G T
Sbjct: 88 TEYVVTITSYDEVEESVPVIGQLT 111
Score = 52.0 bits (123), Expect = 6e-06
Identities = 29/89 (32%), Positives = 45/89 (50%), Gaps = 2/89 (2%)
Query: 1887 LDSPRDLTATEVQSETALLTWRPPRASVTGYLLVYESVDGTVKE--VIVGPDTTSYSLAD 1944
++ P +L A EV S+ L W P + VTGY ++ + ++ + VGP TT+ S+ D
Sbjct: 334 VEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQTTTLSVRD 393
Query: 1945 LSPSTHYTAKIQALNGPLRSNMIQTIFTT 1973
LS T Y + A+ G S I + T
Sbjct: 394 LSADTEYQISVSAMKGMTSSEPISIMEKT 422
Score = 49.3 bits (116), Expect = 4e-05
Identities = 26/85 (30%), Positives = 46/85 (54%), Gaps = 2/85 (2%)
Query: 621 SEVSPPKDLVVTEVTEETVNLAWDNEMR-VTEYLVVYTPTHEGGLEMQFRVPGDQTSTII 679
+EV PP DL + E TV+++W + + Y + PT +G + +F + T T++
Sbjct: 23 AEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTK-EFTLSASTTETLL 81
Query: 680 QELEPGVEYFIRVFAILENKKSIPV 704
EL P EY + + + E ++S+PV
Sbjct: 82 SELVPETEYVVTITSYDEVEESVPV 106
Score = 45.4 bits (106), Expect = 6e-04
Identities = 33/92 (35%), Positives = 49/92 (53%), Gaps = 5/92 (5%)
Query: 616 SGEDCSEVSPPKDLVVTEVTEETVNLAWD-NEMRVTEYLVVYTPTHEGGLEMQFRVPGDQ 674
SGE+ V PP +L+ EV+ + V L W+ + VT Y V+ TP G + V G Q
Sbjct: 329 SGEEV--VEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSV-GPQ 385
Query: 675 TSTI-IQELEPGVEYFIRVFAILENKKSIPVS 705
T+T+ +++L EY I V A+ S P+S
Sbjct: 386 TTTLSVRDLSADTEYQISVSAMKGMTSSEPIS 417
Score = 45.4 bits (106), Expect = 6e-04
Identities = 23/81 (28%), Positives = 40/81 (49%), Gaps = 1/81 (1%)
Query: 1713 PKEVIFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSMVTVDGTKTQTRLVK-LIP 1771
P +I +++ ++W + V +++ P+T G+ G +T T V+ L
Sbjct: 337 PSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQTTTLSVRDLSA 396
Query: 1772 GVEYLVSIIAMKGFEESEPVS 1792
EY +S+ AMKG SEP+S
Sbjct: 397 DTEYQISVSAMKGMTSSEPIS 417
Score = 43.1 bits (100), Expect = 0.003
Identities = 21/81 (25%), Positives = 37/81 (45%), Gaps = 1/81 (1%)
Query: 1876 SSTITAKFTTDLDSPRDLTATEVQSETALLTWRPPRASVTGYLLVYE-SVDGTVKEVIVG 1934
++ + + ++D P DL + T ++W P + GY + + + DG KE +
Sbjct: 14 AALLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLS 73
Query: 1935 PDTTSYSLADLSPSTHYTAKI 1955
TT L++L P T Y I
Sbjct: 74 ASTTETLLSELVPETEYVVTI 94
Score = 40.0 bits (92), Expect = 0.025
Identities = 26/84 (30%), Positives = 41/84 (48%), Gaps = 3/84 (3%)
Query: 893 LDAPRNLRRVSQTDNSITLEWRNGKAAIDSYRIKYAPISGGDHAEVDVPKSQQATTKTTL 952
+D P +L +N++ + W I YRI P + G E + S TT+T L
Sbjct: 25 VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSAS---TTETLL 81
Query: 953 TGLRPGTEYGIGVSAVKEDKESNP 976
+ L P TEY + +++ E +ES P
Sbjct: 82 SELVPETEYVVTITSYDEVEESVP 105
Score = 39.7 bits (91), Expect = 0.033
Identities = 29/103 (28%), Positives = 47/103 (45%), Gaps = 9/103 (8%)
Query: 893 LDAPRNLRRVSQTDNSITLEWRNGKAAIDSYRIKYAPISGGD--HAEVDVPKSQQATTKT 950
++ P NL + + + L W + + Y++ P++ G HA P+ TT
Sbjct: 334 VEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQ----TTTL 389
Query: 951 TLTGLRPGTEYGIGVSAVKEDKESNPATINAATELDTPKDLQV 993
++ L TEY I VSA+K S P +I T+ P +QV
Sbjct: 390 SVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQ---PMKVQV 429
Score = 39.3 bits (90), Expect = 0.043
Identities = 38/175 (21%), Positives = 67/175 (38%), Gaps = 14/175 (8%)
Query: 1789 EPVSGSFTTALDGPSGLVTANITDSEALARWQPAIATVDSYVISYTGEKV--PEITRTVS 1846
E VSG ++ PS L+ ++ W P+ + V Y + T + +V
Sbjct: 326 ELVSGE--EVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVG 383
Query: 1847 GNTVEYALTDLEPATEYTLRIFAEKGPQKSSTI-----TAKFTTDLDSPRDLTATEVQSE 1901
T ++ DL TEY + + A KG S I T ++ R +++++
Sbjct: 384 PQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSR---GVDIKAD 440
Query: 1902 TALLTWRPPRASVTGYLLVYESVDGTVKEVIVGPDTTSYSLADLS--PSTHYTAK 1954
L + ++ V ++ VK + P+ SL S P T +T K
Sbjct: 441 IVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLK 495
Score = 36.6 bits (83), Expect = 0.28
Identities = 20/73 (27%), Positives = 34/73 (46%), Gaps = 1/73 (1%)
Query: 803 LDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQYSIGN 862
+D PS + K + + T ++W KP+ I G +T G L+ + +
Sbjct: 25 VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVD-PTTDGPTKEFTLSASTTETLLSE 83
Query: 863 LKPDTEYEVSLIS 875
L P+TEY V++ S
Sbjct: 84 LVPETEYVVTITS 96
Score = 33.5 bits (75), Expect = 2.4
Identities = 24/82 (29%), Positives = 35/82 (42%), Gaps = 1/82 (1%)
Query: 984 ELDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYSLPT-GQWVGVQLPRNTTSYVLRG 1042
E+D P DL E ++ + W P+ YR+ T G L +TT +L
Sbjct: 24 EVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSASTTETLLSE 83
Query: 1043 LEPGQEYNVLLTAEKGRHKSKP 1064
L P EY V +T+ +S P
Sbjct: 84 LVPETEYVVTITSYDEVEESVP 105
Score = 32.0 bits (71), Expect = 6.9
Identities = 22/89 (24%), Positives = 36/89 (40%), Gaps = 1/89 (1%)
Query: 628 DLVVTEVTEETVNLAWDNEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTIIQELEPGVE 687
DL ++ +T + W T Y + +P +G + V G +TS L P +
Sbjct: 2209 DLKTYQIGWDTFCVKWSPHRAATSYRLKLSPA-DGTRGQEITVRGSETSHCFTGLSPDTD 2267
Query: 688 YFIRVFAILENKKSIPVSARVATYLPAPE 716
Y + VF N + VS + T + E
Sbjct: 2268 YGVTVFVQTPNLEGPGVSVKEHTTVKPTE 2296
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.134 0.416
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 90,982,550
Number of Sequences: 37866
Number of extensions: 4785065
Number of successful extensions: 29529
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 158
Number of HSP's successfully gapped in prelim test: 470
Number of HSP's that attempted gapping in prelim test: 10313
Number of HSP's gapped (non-prelim): 6115
length of query: 2201
length of database: 18,247,518
effective HSP length: 118
effective length of query: 2083
effective length of database: 13,779,330
effective search space: 28702344390
effective search space used: 28702344390
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.