Guide to the Human Genome
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Search of human proteins with 153792298

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|153792298 piwi-like 3 [Homo sapiens]
         (882 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|153792298 piwi-like 3 [Homo sapiens]                              1793   0.0  
gi|66346725 piwi-like 1 [Homo sapiens]                                864   0.0  
gi|221316711 piwi-like 4 [Homo sapiens]                               637   0.0  
gi|209180418 piwi-like 2 [Homo sapiens]                               514   e-145
gi|24431985 piwi-like 2 [Homo sapiens]                                514   e-145
gi|169217928 PREDICTED: similar to piwi like homolog 2 [Homo sap...   171   4e-42
gi|29171734 eukaryotic translation initiation factor 2C, 2 [Homo...   156   7e-38
gi|6912352 eukaryotic translation initiation factor 2C, 1 [Homo ...   147   3e-35
gi|29294647 eukaryotic translation initiation factor 2C, 3 isofo...   144   4e-34
gi|29029593 eukaryotic translation initiation factor 2C, 4 [Homo...   135   2e-31
gi|29337286 eukaryotic translation initiation factor 2C, 3 isofo...   129   1e-29
gi|239750966 PREDICTED: hypothetical protein XP_002347633 [Homo ...    38   0.047
gi|239745372 PREDICTED: hypothetical protein XP_002343483 [Homo ...    38   0.047
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     37   0.11 
gi|112734870 hypothetical protein LOC57648 [Homo sapiens]              35   0.23 
gi|50843837 hypothetical protein LOC55701 [Homo sapiens]               35   0.23 
gi|223633935 hypothetical protein LOC254427 [Homo sapiens]             35   0.31 
gi|51173735 ras responsive element binding protein 1 isoform 2 [...    35   0.31 
gi|51173737 ras responsive element binding protein 1 isoform 1 [...    35   0.31 
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         35   0.31 
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]       35   0.40 
gi|18079216 CASK interacting protein 1 [Homo sapiens]                  34   0.52 
gi|239746530 PREDICTED: hypothetical protein XP_002343754 [Homo ...    34   0.52 
gi|239751186 PREDICTED: WD repeat domain 81 [Homo sapiens]             34   0.68 
gi|239749150 PREDICTED: hypothetical protein XP_002346928 [Homo ...    34   0.68 
gi|19924103 synapsin II isoform IIa [Homo sapiens]                     34   0.68 
gi|193082982 zinc finger protein 837 isoform 1 [Homo sapiens]          34   0.68 
gi|193082980 zinc finger protein 837 isoform 2 [Homo sapiens]          34   0.68 
gi|19924101 synapsin II isoform IIb [Homo sapiens]                     34   0.68 
gi|238908524 hypothetical protein LOC389333 [Homo sapiens]             33   0.89 

>gi|153792298 piwi-like 3 [Homo sapiens]
          Length = 882

 Score = 1793 bits (4645), Expect = 0.0
 Identities = 882/882 (100%), Positives = 882/882 (100%)

Query: 1   MPGRARTRARGRARRRESYQQEAPGGPRAPGSATTQEPPQLQSTPRPLQEEVPVVRPLQP 60
           MPGRARTRARGRARRRESYQQEAPGGPRAPGSATTQEPPQLQSTPRPLQEEVPVVRPLQP
Sbjct: 1   MPGRARTRARGRARRRESYQQEAPGGPRAPGSATTQEPPQLQSTPRPLQEEVPVVRPLQP 60

Query: 61  RAARGGAGGGAQSQGVKEPGPEAGLHTAPLQERRIGGVFQDLVVNTRQDMKHVKDSKTGS 120
           RAARGGAGGGAQSQGVKEPGPEAGLHTAPLQERRIGGVFQDLVVNTRQDMKHVKDSKTGS
Sbjct: 61  RAARGGAGGGAQSQGVKEPGPEAGLHTAPLQERRIGGVFQDLVVNTRQDMKHVKDSKTGS 120

Query: 121 EGTVVQLLANHFRVISRPQWVAYKYNVDYKPDIEDGNLRTILLDQHRRKFGERHIFDGNS 180
           EGTVVQLLANHFRVISRPQWVAYKYNVDYKPDIEDGNLRTILLDQHRRKFGERHIFDGNS
Sbjct: 121 EGTVVQLLANHFRVISRPQWVAYKYNVDYKPDIEDGNLRTILLDQHRRKFGERHIFDGNS 180

Query: 181 LLLSRPLKERRVEWLSTTKDKNIVKITVEFSKELTPTSPDCLRYYNILFRRTFKLLDFEQ 240
           LLLSRPLKERRVEWLSTTKDKNIVKITVEFSKELTPTSPDCLRYYNILFRRTFKLLDFEQ
Sbjct: 181 LLLSRPLKERRVEWLSTTKDKNIVKITVEFSKELTPTSPDCLRYYNILFRRTFKLLDFEQ 240

Query: 241 VGRNYYTKKKAIQLYRHGTSLEIWLGYVTSVLQYENSITLCADVSHKLLRIETAYDFIKR 300
           VGRNYYTKKKAIQLYRHGTSLEIWLGYVTSVLQYENSITLCADVSHKLLRIETAYDFIKR
Sbjct: 241 VGRNYYTKKKAIQLYRHGTSLEIWLGYVTSVLQYENSITLCADVSHKLLRIETAYDFIKR 300

Query: 301 TSAQAQTGNIREEVTNKLIGSIVLTKYNNKTYRVDDIDWKQNPEDTFNKSDGSKITYIDY 360
           TSAQAQTGNIREEVTNKLIGSIVLTKYNNKTYRVDDIDWKQNPEDTFNKSDGSKITYIDY
Sbjct: 301 TSAQAQTGNIREEVTNKLIGSIVLTKYNNKTYRVDDIDWKQNPEDTFNKSDGSKITYIDY 360

Query: 361 YRQQHKEIVTVKKQPLLVSQGRWKKGLTGTQREPILLIPQLCHMTGLTDEICKDYSIVKE 420
           YRQQHKEIVTVKKQPLLVSQGRWKKGLTGTQREPILLIPQLCHMTGLTDEICKDYSIVKE
Sbjct: 361 YRQQHKEIVTVKKQPLLVSQGRWKKGLTGTQREPILLIPQLCHMTGLTDEICKDYSIVKE 420

Query: 421 LAKHTRLSPRRRHHTLKEFINTLQDNKKVRELLQLWDLKFDTNFLSVPGRVLKNANIVQG 480
           LAKHTRLSPRRRHHTLKEFINTLQDNKKVRELLQLWDLKFDTNFLSVPGRVLKNANIVQG
Sbjct: 421 LAKHTRLSPRRRHHTLKEFINTLQDNKKVRELLQLWDLKFDTNFLSVPGRVLKNANIVQG 480

Query: 481 RRMVKANSQGDWSREIRELPLLNAMPLHSWLILYSRSSHREAMSLKGHLQSVTAPMGITM 540
           RRMVKANSQGDWSREIRELPLLNAMPLHSWLILYSRSSHREAMSLKGHLQSVTAPMGITM
Sbjct: 481 RRMVKANSQGDWSREIRELPLLNAMPLHSWLILYSRSSHREAMSLKGHLQSVTAPMGITM 540

Query: 541 KPAEMIEVDGDANSYIDTLRKYTRPTLQMGMSCLLVFKVICILPNDDKRRYDSIKRYLCT 600
           KPAEMIEVDGDANSYIDTLRKYTRPTLQMGMSCLLVFKVICILPNDDKRRYDSIKRYLCT
Sbjct: 541 KPAEMIEVDGDANSYIDTLRKYTRPTLQMGMSCLLVFKVICILPNDDKRRYDSIKRYLCT 600

Query: 601 KCPIPSQCVVKKTLEKVQARTIVTKIAQQMNCKMGGALWKVETDVQRTMFVGIDCFHDIV 660
           KCPIPSQCVVKKTLEKVQARTIVTKIAQQMNCKMGGALWKVETDVQRTMFVGIDCFHDIV
Sbjct: 601 KCPIPSQCVVKKTLEKVQARTIVTKIAQQMNCKMGGALWKVETDVQRTMFVGIDCFHDIV 660

Query: 661 NRQKSIAGFVASTNAELTKWYSQCVIQKTGEELVKELEICLKAALDVWCKNESSMPHSVI 720
           NRQKSIAGFVASTNAELTKWYSQCVIQKTGEELVKELEICLKAALDVWCKNESSMPHSVI
Sbjct: 661 NRQKSIAGFVASTNAELTKWYSQCVIQKTGEELVKELEICLKAALDVWCKNESSMPHSVI 720

Query: 721 VYRDGVGDGQLQALLDHEAKKMSTYLKTISPNNFTLAFIVVKKRINTRFFLKHGSNFQNP 780
           VYRDGVGDGQLQALLDHEAKKMSTYLKTISPNNFTLAFIVVKKRINTRFFLKHGSNFQNP
Sbjct: 721 VYRDGVGDGQLQALLDHEAKKMSTYLKTISPNNFTLAFIVVKKRINTRFFLKHGSNFQNP 780

Query: 781 PPGTVIDVELTRNEWYDFFIVSQSVQDGTVTPTHYNVIYDTIGLSPDTVQRLTYCLCHMY 840
           PPGTVIDVELTRNEWYDFFIVSQSVQDGTVTPTHYNVIYDTIGLSPDTVQRLTYCLCHMY
Sbjct: 781 PPGTVIDVELTRNEWYDFFIVSQSVQDGTVTPTHYNVIYDTIGLSPDTVQRLTYCLCHMY 840

Query: 841 YNLPGIIRVPAPCHYAHKLAYLVGQSIHQEPNRSLSTRLFYL 882
           YNLPGIIRVPAPCHYAHKLAYLVGQSIHQEPNRSLSTRLFYL
Sbjct: 841 YNLPGIIRVPAPCHYAHKLAYLVGQSIHQEPNRSLSTRLFYL 882


>gi|66346725 piwi-like 1 [Homo sapiens]
          Length = 861

 Score =  864 bits (2233), Expect = 0.0
 Identities = 449/889 (50%), Positives = 598/889 (67%), Gaps = 35/889 (3%)

Query: 1   MPGRARTRARGRARRRESYQQEAPGGPRAPGSATTQEPPQLQSTPRPLQEEVPVVRPLQP 60
           M GRAR RARGRAR +E+ Q          GS  +Q+P  +Q  P+P     P    L  
Sbjct: 1   MTGRARARARGRARGQETAQ--------LVGSTASQQPGYIQPRPQP----PPAEGELFG 48

Query: 61  RAA-RGGAGGGAQSQGVKEPGPEAGLHTAPLQERRIGGV---FQDLVVNTRQDMKHVKDS 116
           R   RG AGG A+SQG++     AG     L ER  GG    F DL VNTRQ++ HVK+S
Sbjct: 49  RGRQRGTAGGTAKSQGLQI---SAGFQELSLAER--GGRRRDFHDLGVNTRQNLDHVKES 103

Query: 117 KTGSEGTVVQLLANHFRVISRPQWVAYKYNVDYKPDIEDGNLRTILLDQHRRKFGERHIF 176
           KTGS G +V+L  NHFR+ SRPQW  Y+Y++DY P +E   LR+ LL QH    G+ H F
Sbjct: 104 KTGSSGIIVRLSTNHFRLTSRPQWALYQYHIDYNPLMEARRLRSALLFQHEDLIGKCHAF 163

Query: 177 DGNSLLLSRPLKERRVEWLSTTKDKNIVKITVEFSKELTPTSPDCLRYYNILFRRTFKLL 236
           DG  L L + L+++  E  S T++   V+IT+  + EL PTSP CL++YNI+FRR  K++
Sbjct: 164 DGTILFLPKRLQQKVTEVFSKTRNGEDVRITITLTNELPPTSPTCLQFYNIIFRRLLKIM 223

Query: 237 DFEQVGRNYYTKKKAIQLYRHGTSLEIWLGYVTSVLQYENSITLCADVSHKLLRIETAYD 296
           + +Q+GRNYY     I +  H   L IW G+ TS+LQYENSI LC DVSHK+LR ET  D
Sbjct: 224 NLQQIGRNYYNPNDPIDIPSH--RLVIWPGFTTSILQYENSIMLCTDVSHKVLRSETVLD 281

Query: 297 FIKRTSAQAQTGNIREEVTNKLIGSIVLTKYNNKTYRVDDIDWKQNPEDTFNKSDGSKIT 356
           F+     Q +    +E+V+ +LIG +VLTKYNNKTYRVDDIDW QNP+ TF K+DGS+++
Sbjct: 282 FMFNFYHQTEEHKFQEQVSKELIGLVVLTKYNNKTYRVDDIDWDQNPKSTFKKADGSEVS 341

Query: 357 YIDYYRQQHKEIVTVKKQPLLVSQGRWKKGLTGTQREPILLIPQLCHMTGLTDEICKDYS 416
           +++YYR+Q+ + +T  KQP+LVSQ + ++G  GT   P +LIP+LC++TGLTD++  D++
Sbjct: 342 FLEYYRKQYNQEITDLKQPVLVSQPKRRRGPGGTLPGPAMLIPELCYLTGLTDKMRNDFN 401

Query: 417 IVKELAKHTRLSPRRRHHTLKEFINTLQDNKKVRELLQLWDLKFDTNFLSVPGRVLKNAN 476
           ++K+LA HTRL+P +R   +   I+ +  N  V+  L+ W L FD+N LS  GR+L+   
Sbjct: 402 VMKDLAVHTRLTPEQRQREVGRLIDYIHKNDNVQRELRDWGLSFDSNLLSFSGRILQTEK 461

Query: 477 IVQGRRMVKANSQ-GDWSREIRELPLLNAMPLHSWLILYSRSSHREAMSLKGHLQSVTAP 535
           I QG +    N Q  DWS+E R  PL++  PL +WL++Y+R ++  A SL  +L  VT  
Sbjct: 462 IHQGGKTFDYNPQFADWSKETRGAPLISVKPLDNWLLIYTRRNYEAANSLIQNLFKVTPA 521

Query: 536 MGITMKPAEMIEVDGDANSYIDTLRKYTRPTLQMGMSCLLVFKVICILPNDDKRRYDSIK 595
           MG+ M+ A MIEVD    +Y+  L++      Q+         V+C+L ++ K +YD+IK
Sbjct: 522 MGMQMRKAIMIEVDDRTEAYLRVLQQKVTADTQI---------VVCLLSSNRKDKYDAIK 572

Query: 596 RYLCTKCPIPSQCVVKKTLEKVQ-ARTIVTKIAQQMNCKMGGALWKVETDVQRTMFVGID 654
           +YLCT CP PSQCVV +TL K Q    I TKIA QMNCKMGG LW+V+  ++  M VGID
Sbjct: 573 KYLCTDCPTPSQCVVARTLGKQQTVMAIATKIALQMNCKMGGELWRVDIPLKLVMIVGID 632

Query: 655 CFHDIVNRQKSIAGFVASTNAELTKWYSQCVIQKTGEELVKELEICLKAALDVWCKNESS 714
           C+HD+   ++SIAGFVAS N  +T+W+S+C+ Q  G+ELV  L++CL+AAL  W      
Sbjct: 633 CYHDMTAGRRSIAGFVASINEGMTRWFSRCIFQDRGQELVDGLKVCLQAALRAWNSCNEY 692

Query: 715 MPHSVIVYRDGVGDGQLQALLDHEAKKMSTYLKTISPN-NFTLAFIVVKKRINTRFFLKH 773
           MP  +IVYRDGVGDGQL+ L+++E  +    LK+I    N  L  IVVKKR+NTRFF + 
Sbjct: 693 MPSRIIVYRDGVGDGQLKTLVNYEVPQFLDCLKSIGRGYNPRLTVIVVKKRVNTRFFAQS 752

Query: 774 GSNFQNPPPGTVIDVELTRNEWYDFFIVSQSVQDGTVTPTHYNVIYDTIGLSPDTVQRLT 833
           G   QNP PGTVIDVE+TR EWYDFFIVSQ+V+ G+V+PTHYNVIYD  GL PD +QRLT
Sbjct: 753 GGRLQNPLPGTVIDVEVTRPEWYDFFIVSQAVRSGSVSPTHYNVIYDNSGLKPDHIQRLT 812

Query: 834 YCLCHMYYNLPGIIRVPAPCHYAHKLAYLVGQSIHQEPNRSLSTRLFYL 882
           Y LCH+YYN PG+IRVPAPC YAHKLA+LVGQSIH+EPN SLS RL+YL
Sbjct: 813 YKLCHIYYNWPGVIRVPAPCQYAHKLAFLVGQSIHREPNLSLSNRLYYL 861


>gi|221316711 piwi-like 4 [Homo sapiens]
          Length = 852

 Score =  637 bits (1643), Expect = 0.0
 Identities = 345/886 (38%), Positives = 519/886 (58%), Gaps = 38/886 (4%)

Query: 1   MPGRARTRARGRARRRESYQQEAPGGPRAPGSATTQEPPQLQSTPRPLQEEVPVVRPLQP 60
           M GRAR +ARG AR                 S +  E  ++Q++P P   ++        
Sbjct: 1   MSGRARVKARGIAR-----------------SPSATEVGRIQASPLPRSVDLSN----NE 39

Query: 61  RAARGGAGGGAQSQGVKEPGPEAGLHTAPLQERRIGGV--FQDLVVNTRQDMKHVKDSKT 118
            ++  G  G ++     + G  +G   +   ER +     F DL + TR+ + HV++ KT
Sbjct: 40  ASSSNGFLGTSRISTNDKYGISSGDAGSTFMERGVKNKQDFMDLSICTREKLAHVRNCKT 99

Query: 119 GSEGTVVQLLANHFRVISRPQWVAYKYNVDYKPDIEDGNLRTILLDQHRRKFGERHIFDG 178
           GS G  V+L+ N F +     W  Y+Y+V Y PD+    LR  LL  H     +   FDG
Sbjct: 100 GSSGIPVKLVTNLFNLDFPQDWQLYQYHVTYIPDLASRRLRIALLYSHSELSNKAKAFDG 159

Query: 179 NSLLLSRPLKERRVEWLSTTKDKNIVKITVEFSKELTPTSPDCLRYYNILFRRTFKLLDF 238
             L LS+ L+E+  E  S T+    +K+T+   +EL  +SP C++ +NI+FR+  K L  
Sbjct: 160 AILFLSQKLEEKVTELSSETQRGETIKMTITLKRELPSSSPVCIQVFNIIFRKILKKLSM 219

Query: 239 EQVGRNYYTKKKAIQLYRHGTSLEIWLGYVTSVLQYENSITLCADVSHKLLRIETAYDFI 298
            Q+GRN+Y   + +++ +H   L +W G+  SV  +E  +   ADVS+K+LR ET  +F+
Sbjct: 220 YQIGRNFYNPSEPMEIPQH--KLSLWPGFAISVSYFERKLLFSADVSYKVLRNETVLEFM 277

Query: 299 KRTSAQAQTGNIREEVTNKLIGSIVLTKYNNKTYRVDDIDWKQNPEDTFNKSDGSKITYI 358
                +       +    +LIG IVLT+YNN+TY +DDIDW   P  TF K DG++ITY+
Sbjct: 278 TALCQRTGLSCFTQTCEKQLIGLIVLTRYNNRTYSIDDIDWSVKPTHTFQKRDGTEITYV 337

Query: 359 DYYRQQHKEIVTVKKQPLLVSQGRWKKGLTGTQREPILLIPQLCHMTGLTDEICKDYSIV 418
           DYY+QQ+   V+   QP+LVS  + KK    ++ +   LIP+LC +TGLTD+   D+ ++
Sbjct: 338 DYYKQQYDITVSDLNQPMLVSLLK-KKRNDNSEAQLAHLIPELCFLTGLTDQATSDFQLM 396

Query: 419 KELAKHTRLSPRRRHHTLKEFINTLQDNKKVRELLQLWDLKFDTNFLSVPGRVLKNANIV 478
           K +A+ TRLSP  R   L   ++ +Q N   R  L+ W L F +  +S+ GR++ +  I+
Sbjct: 397 KAVAEKTRLSPSGRQQRLARLVDNIQRNTNARFELETWGLHFGSQ-ISLTGRIVPSEKIL 455

Query: 479 QGRRMVKANSQGDWSREIRELPLLNAMPLHSWLILYSRSSHREAMSLKGHLQSVTAPMGI 538
               + +  S  DWS++IR   +LNA  L++WLIL S  +   A S    L+ V   MG 
Sbjct: 456 MQDHICQPVSAADWSKDIRTCKILNAQSLNTWLILCSDRTEYVAESFLNCLRRVAGSMGF 515

Query: 539 TMKPAEMIEVDGDANSYIDTLRKYTRPTLQMGMSCLLVFKVICILPNDDKRRYDSIKRYL 598
            +   ++I+V  +  +++  +++Y  P +Q+         V+CILP++ K  YDSIK+YL
Sbjct: 516 NVDYPKIIKVQENPAAFVRAIQQYVDPDVQL---------VMCILPSNQKTYYDSIKKYL 566

Query: 599 CTKCPIPSQCVVKKTLEKV-QARTIVTKIAQQMNCKMGGALWKVETDVQRTMFVGIDCFH 657
            + CP+PSQCV+ +TL K     +I TKIA QM CK+GG LW VE  ++  M VGID   
Sbjct: 567 SSDCPVPSQCVLARTLNKQGMMMSIATKIAMQMTCKLGGELWAVEIPLKSLMVVGIDVCK 626

Query: 658 DIVNRQKSIAGFVASTNAELTKWYSQCVIQKTGEELVKELEICLKAALDVWCKNESSMPH 717
           D +++   + G VAS N  +T+W+S+C++Q+T  ++   L++ +  AL+ W K    +P 
Sbjct: 627 DALSKDVMVVGCVASVNPRITRWFSRCILQRTMTDVADCLKVFMTGALNKWYKYNHDLPA 686

Query: 718 SVIVYRDGVGDGQLQALLDHEAKKM-STYLKTISPNNFTLAFIVVKKRINTRFFLKHGSN 776
            +IVYR GVGDGQL+ L+++E  ++ S+  ++ S  +  L+ IVV+K+   RFF +    
Sbjct: 687 RIIVYRAGVGDGQLKTLIEYEVPQLLSSVAESSSNTSSRLSVIVVRKKCMPRFFTEMNRT 746

Query: 777 FQNPPPGTVIDVELTRNEWYDFFIVSQSVQDGTVTPTHYNVIYDTIGLSPDTVQRLTYCL 836
            QNPP GTV+D E TRNEWYDF+++SQ    GTV+PT+YNVIYD  GL PD +QRLT+ L
Sbjct: 747 VQNPPLGTVVDSEATRNEWYDFYLISQVACRGTVSPTYYNVIYDDNGLKPDHMQRLTFKL 806

Query: 837 CHMYYNLPGIIRVPAPCHYAHKLAYLVGQSIHQEPNRSLSTRLFYL 882
           CH+YYN PGI+ VPAPC YAHKL +LV QSIH+EP+  L+  LFYL
Sbjct: 807 CHLYYNWPGIVSVPAPCQYAHKLTFLVAQSIHKEPSLELANHLFYL 852


>gi|209180418 piwi-like 2 [Homo sapiens]
          Length = 973

 Score =  514 bits (1323), Expect = e-145
 Identities = 275/773 (35%), Positives = 444/773 (57%), Gaps = 22/773 (2%)

Query: 117 KTGSEGTVVQLLANHFRVISRPQWVAYKYNVDYKPDIEDGNLRTILLDQHRRKFGERHIF 176
           K GS+GT   L  N  ++    + V Y+Y+V + P++E  ++R  +L  H+   G    F
Sbjct: 216 KQGSKGTPQSLGLNLVKIQCHNEAV-YQYHVTFSPNVECKSMRFGMLKDHQAVTGNVTAF 274

Query: 177 DGNSLLLSRPLKERRVEWLSTTK--DKNIVKITVEFSKELTPTSPDCLRYYNILFRRTFK 234
           DG+ L L  P+K ++V  L + +  D   + I ++ +K L P S  C+ +YN++FRR  K
Sbjct: 275 DGSILYL--PVKLQQVLELKSQRKTDSAEISIKIQMTKILEPCSDLCIPFYNVVFRRVMK 332

Query: 235 LLDFEQVGRNYYTKKKAIQLYRHGTSLEIWLGYVTSVLQYENSITLCADVSHKLLRIETA 294
           LLD + VGRN+Y    A+ L +H   L+IW GY  S+ + +  + L ADVSHK++R +  
Sbjct: 333 LLDMKLVGRNFYDPTSAMVLQQH--RLQIWPGYAASIRRTDGGLFLLADVSHKVIRNDCV 390

Query: 295 YDFIKRTSAQAQTGNIREEVTNKLIGSIVLTKYNNKTYRVDDIDWKQNPEDTFNKSDGSK 354
            D +     Q    + ++E T  L+G+IV+T+YNN+TYR+DD+DW + P+D+F  SDG +
Sbjct: 391 LD-VMHAIYQQNKEHFQDECTKLLVGNIVITRYNNRTYRIDDVDWNKTPKDSFTMSDGKE 449

Query: 355 ITYIDYYRQQHKEIVTVKKQPLLVSQGRWKKGLTGTQ-REPILLIPQLCHMTGLTDEICK 413
           IT+++YY + +   V  + QPLL+ +   ++   G   +  ILL+P+L  MTG+ +++ K
Sbjct: 450 ITFLEYYSKNYGITVKEEDQPLLIHRPSERQDNHGMLLKGEILLLPELSFMTGIPEKMKK 509

Query: 414 DYSIVKELAKHTRLSPRRRHHTLKEFINTLQDNKKVRELLQLWDLKFDTNFLSVPGRVLK 473
           D+  +K+LA+   LSP++ H  L+  +  +  N+     L  W L+   +   + GRVL 
Sbjct: 510 DFRAMKDLAQQINLSPKQHHSALECLLQRIAKNEAATNELMRWGLRLQKDVHKIEGRVLP 569

Query: 474 NANIVQGRRMVKANSQGDWSREIRELPLLNAMPLHSWLILYSRSSHREAMSLKGHLQSVT 533
              I         + + +W +E+   P +  +P+H W + Y + +  +A  L   L+ + 
Sbjct: 570 MERINLKNTSFITSQELNWVKEVTRDPSILTIPMHFWALFYPKRAMDQARELVNMLEKIA 629

Query: 534 APMGITMKPAEMIEVDGDA-NSYIDTLRKYTRPTLQMGMSCLLVFKVICIL--PNDDKRR 590
            P+G+ M P   +E+  D   +Y+ T++       ++ M       V+CI+  P DD   
Sbjct: 630 GPIGMRMSPPAWVELKDDRIETYVRTIQSTLGAEGKIQM-------VVCIIMGPRDDL-- 680

Query: 591 YDSIKRYLCTKCPIPSQCVVKKTL-EKVQARTIVTKIAQQMNCKMGGALWKVETDVQRTM 649
           Y +IK+  C + P+PSQ V  +T+ +  + R++  KI  Q+NCK+GG LW V+  +++ M
Sbjct: 681 YGAIKKLCCVQSPVPSQVVNVRTIGQPTRLRSVAQKILLQINCKLGGELWGVDIPLKQLM 740

Query: 650 FVGIDCFHDIVNRQKSIAGFVASTNAELTKWYSQCVIQKTGEELVKELEICLKAALDVWC 709
            +G+D +HD     +S+ GFVAS N  LTKWYS+ V Q   +E+V  L++CL  +L  + 
Sbjct: 741 VIGMDVYHDPSRGMRSVVGFVASINLTLTKWYSRVVFQMPHQEIVDSLKLCLVGSLKKFY 800

Query: 710 KNESSMPHSVIVYRDGVGDGQLQALLDHEAKKMSTYLKTISPNNFTLAFIVVKKRINTRF 769
           +    +P  ++VYRDGV DGQL+ + ++E  ++    +        +   VV+K+I+T  
Sbjct: 801 EVNHCLPEKIVVYRDGVSDGQLKTVANYEIPQLQKCFEAFENYQPKMVVFVVQKKISTNL 860

Query: 770 FLKHGSNFQNPPPGTVIDVELTRNEWYDFFIVSQSVQDGTVTPTHYNVIYDTIGLSPDTV 829
           +L    NF  P PGTV+D  +T  EW DF++++  V+ G   PTHY  + +T  LSPD +
Sbjct: 861 YLAAPQNFVTPTPGTVVDHTITSCEWVDFYLLAHHVRQGCGIPTHYVCVLNTANLSPDHM 920

Query: 830 QRLTYCLCHMYYNLPGIIRVPAPCHYAHKLAYLVGQSIHQEPNRSLSTRLFYL 882
           QRLT+ LCHMY+N PG IRVPAPC YAHKLA+L G  +H EP   L   LF+L
Sbjct: 921 QRLTFKLCHMYWNWPGTIRVPAPCKYAHKLAFLSGHILHHEPAIQLCENLFFL 973


>gi|24431985 piwi-like 2 [Homo sapiens]
          Length = 973

 Score =  514 bits (1323), Expect = e-145
 Identities = 275/773 (35%), Positives = 444/773 (57%), Gaps = 22/773 (2%)

Query: 117 KTGSEGTVVQLLANHFRVISRPQWVAYKYNVDYKPDIEDGNLRTILLDQHRRKFGERHIF 176
           K GS+GT   L  N  ++    + V Y+Y+V + P++E  ++R  +L  H+   G    F
Sbjct: 216 KQGSKGTPQSLGLNLVKIQCHNEAV-YQYHVTFSPNVECKSMRFGMLKDHQAVTGNVTAF 274

Query: 177 DGNSLLLSRPLKERRVEWLSTTK--DKNIVKITVEFSKELTPTSPDCLRYYNILFRRTFK 234
           DG+ L L  P+K ++V  L + +  D   + I ++ +K L P S  C+ +YN++FRR  K
Sbjct: 275 DGSILYL--PVKLQQVLELKSQRKTDSAEISIKIQMTKILEPCSDLCIPFYNVVFRRVMK 332

Query: 235 LLDFEQVGRNYYTKKKAIQLYRHGTSLEIWLGYVTSVLQYENSITLCADVSHKLLRIETA 294
           LLD + VGRN+Y    A+ L +H   L+IW GY  S+ + +  + L ADVSHK++R +  
Sbjct: 333 LLDMKLVGRNFYDPTSAMVLQQH--RLQIWPGYAASIRRTDGGLFLLADVSHKVIRNDCV 390

Query: 295 YDFIKRTSAQAQTGNIREEVTNKLIGSIVLTKYNNKTYRVDDIDWKQNPEDTFNKSDGSK 354
            D +     Q    + ++E T  L+G+IV+T+YNN+TYR+DD+DW + P+D+F  SDG +
Sbjct: 391 LD-VMHAIYQQNKEHFQDECTKLLVGNIVITRYNNRTYRIDDVDWNKTPKDSFTMSDGKE 449

Query: 355 ITYIDYYRQQHKEIVTVKKQPLLVSQGRWKKGLTGTQ-REPILLIPQLCHMTGLTDEICK 413
           IT+++YY + +   V  + QPLL+ +   ++   G   +  ILL+P+L  MTG+ +++ K
Sbjct: 450 ITFLEYYSKNYGITVKEEDQPLLIHRPSERQDNHGMLLKGEILLLPELSFMTGIPEKMKK 509

Query: 414 DYSIVKELAKHTRLSPRRRHHTLKEFINTLQDNKKVRELLQLWDLKFDTNFLSVPGRVLK 473
           D+  +K+LA+   LSP++ H  L+  +  +  N+     L  W L+   +   + GRVL 
Sbjct: 510 DFRAMKDLAQQINLSPKQHHSALECLLQRIAKNEAATNELMRWGLRLQKDVHKIEGRVLP 569

Query: 474 NANIVQGRRMVKANSQGDWSREIRELPLLNAMPLHSWLILYSRSSHREAMSLKGHLQSVT 533
              I         + + +W +E+   P +  +P+H W + Y + +  +A  L   L+ + 
Sbjct: 570 MERINLKNTSFITSQELNWVKEVTRDPSILTIPMHFWALFYPKRAMDQARELVNMLEKIA 629

Query: 534 APMGITMKPAEMIEVDGDA-NSYIDTLRKYTRPTLQMGMSCLLVFKVICIL--PNDDKRR 590
            P+G+ M P   +E+  D   +Y+ T++       ++ M       V+CI+  P DD   
Sbjct: 630 GPIGMRMSPPAWVELKDDRIETYVRTIQSTLGAEGKIQM-------VVCIIMGPRDDL-- 680

Query: 591 YDSIKRYLCTKCPIPSQCVVKKTL-EKVQARTIVTKIAQQMNCKMGGALWKVETDVQRTM 649
           Y +IK+  C + P+PSQ V  +T+ +  + R++  KI  Q+NCK+GG LW V+  +++ M
Sbjct: 681 YGAIKKLCCVQSPVPSQVVNVRTIGQPTRLRSVAQKILLQINCKLGGELWGVDIPLKQLM 740

Query: 650 FVGIDCFHDIVNRQKSIAGFVASTNAELTKWYSQCVIQKTGEELVKELEICLKAALDVWC 709
            +G+D +HD     +S+ GFVAS N  LTKWYS+ V Q   +E+V  L++CL  +L  + 
Sbjct: 741 VIGMDVYHDPSRGMRSVVGFVASINLTLTKWYSRVVFQMPHQEIVDSLKLCLVGSLKKFY 800

Query: 710 KNESSMPHSVIVYRDGVGDGQLQALLDHEAKKMSTYLKTISPNNFTLAFIVVKKRINTRF 769
           +    +P  ++VYRDGV DGQL+ + ++E  ++    +        +   VV+K+I+T  
Sbjct: 801 EVNHCLPEKIVVYRDGVSDGQLKTVANYEIPQLQKCFEAFENYQPKMVVFVVQKKISTNL 860

Query: 770 FLKHGSNFQNPPPGTVIDVELTRNEWYDFFIVSQSVQDGTVTPTHYNVIYDTIGLSPDTV 829
           +L    NF  P PGTV+D  +T  EW DF++++  V+ G   PTHY  + +T  LSPD +
Sbjct: 861 YLAAPQNFVTPTPGTVVDHTITSCEWVDFYLLAHHVRQGCGIPTHYVCVLNTANLSPDHM 920

Query: 830 QRLTYCLCHMYYNLPGIIRVPAPCHYAHKLAYLVGQSIHQEPNRSLSTRLFYL 882
           QRLT+ LCHMY+N PG IRVPAPC YAHKLA+L G  +H EP   L   LF+L
Sbjct: 921 QRLTFKLCHMYWNWPGTIRVPAPCKYAHKLAFLSGHILHHEPAIQLCENLFFL 973


>gi|169217928 PREDICTED: similar to piwi like homolog 2 [Homo
           sapiens]
          Length = 349

 Score =  171 bits (432), Expect = 4e-42
 Identities = 92/297 (30%), Positives = 158/297 (53%), Gaps = 13/297 (4%)

Query: 413 KDYSIVKELAKHTRLSPRRRHHTLKEFINTLQDNKKVRELLQLWDLKFDTNFLSVPGRVL 472
           KD+  +K+LA+   LSP++ H  L+  +  +  N+     L  W L+   +   + GRVL
Sbjct: 3   KDFRAMKDLAQQINLSPKQHHSALECLLQRIAKNEAATNELMRWGLRLQKDVHKIEGRVL 62

Query: 473 KNANIVQGRRMVKANSQGDWSREIRELPLLNAMPLHSWLILYSRSSHREAMSLKGHLQSV 532
               I         + + +W +E+   P +  +P+H W + Y + +  +A  L   L+ +
Sbjct: 63  PMERINLKNTSFITSQELNWVKEVTRDPSILTIPMHFWALFYPKRAMDQARELVNMLEKI 122

Query: 533 TAPMGITMKPAEMIEVDGDA-NSYIDTLRKYTRPTLQMGMSCLLVFKVICIL--PNDDKR 589
             P+G+ M P   +E+  D   +Y+ T++       ++ M       V+CI+  P DD  
Sbjct: 123 AGPIGMRMSPPAWVELKDDRIETYVRTIQSTLGAEGKIQM-------VVCIIMGPRDDL- 174

Query: 590 RYDSIKRYLCTKCPIPSQCVVKKTL-EKVQARTIVTKIAQQMNCKMGGALWKVETDVQRT 648
            Y +IK+  C + P+PSQ V  +T+ +  + R++  KI  Q+NCK+GG LW V+  +++ 
Sbjct: 175 -YGAIKKLCCVQSPVPSQVVNVRTIGQPTRLRSVAQKILLQINCKLGGELWGVDIPLKQL 233

Query: 649 MFVGIDCFHDIVNRQKSIAGFVASTNAELTKWYSQCVIQKTGEELVKELEICLKAAL 705
           M +G+D +HD     +S+ GFVAS N  LTKWYS+ V Q   +E+V  L++CL  +L
Sbjct: 234 MVIGMDVYHDPSRGMRSVVGFVASINLTLTKWYSRVVFQMPHQEIVDSLKLCLVGSL 290


>gi|29171734 eukaryotic translation initiation factor 2C, 2 [Homo
           sapiens]
          Length = 859

 Score =  156 bits (395), Expect = 7e-38
 Identities = 200/814 (24%), Positives = 345/814 (42%), Gaps = 105/814 (12%)

Query: 119 GSEGTVVQLLANHFRVISRPQWVAYKYNVDYKPDIEDGNLRTILLD---QHRRK--FGER 173
           G+ G  ++L AN F +   P+   Y Y +D KP+     +   +++   QH +   FG+R
Sbjct: 32  GTSGRTIKLQANFFEM-DIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDR 90

Query: 174 H-IFDGNSLLLSR---PLKERRVEWLSTT----KDKNIVKITVEF-------------SK 212
             +FDG   L +    P+   +VE   T     KD+ I K+++++             S 
Sbjct: 91  KPVFDGRKNLYTAMPLPIGRDKVELEVTLPGEGKDR-IFKVSIKWVSCVSLQALHDALSG 149

Query: 213 ELTPTSPDCLRYYNILFRRTFKLLDFEQVGRNYYTKKKAIQLYRHGTSLEIWLGYVTSVL 272
            L     + ++  +++ R     + +  VGR+++T  +       G   E+W G+  SV 
Sbjct: 150 RLPSVPFETIQALDVVMRH-LPSMRYTPVGRSFFTASEGCS-NPLGGGREVWFGFHQSVR 207

Query: 273 QYENSITLCADVSHKLLR-----IETAYDFIKRTSAQAQ----TGNIREEVTNKLIG--- 320
                + L  DVS          IE   + +   S + Q    T + R + T ++ G   
Sbjct: 208 PSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKV 267

Query: 321 SIVLTKYNNKTYRVDDIDWKQNPEDTFNKSDGS----KITYIDYYRQQHKEIVTVKKQPL 376
            I       + YRV ++  +     TF     S    + T   Y++ +HK ++     P 
Sbjct: 268 EITHCGQMKRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPC 327

Query: 377 LVSQGRWKKGLTGTQREPILLIPQLCHMTGLTDEICK--DYSIVKELAKHTRLSPRRRHH 434
           L           G +++   L  ++C++      I K  D      +    R +P R+  
Sbjct: 328 LQ---------VGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEE 378

Query: 435 TLKEFIN-TLQDNKKVRELLQLWDLKFDTNFLSVPGRVLKNANIVQGRR--MVKANSQGD 491
             K   + +   +  VRE    + +        V GRVL+  +I+ G R   +    QG 
Sbjct: 379 ISKLMRSASFNTDPYVRE----FGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGV 434

Query: 492 WSREIRELPLLNAMPLHSWLILYSRSSHREAMSLKGHLQSVT---------APMGITMKP 542
           W  ++R       + +  W I    +  R+   +  HL+S T         A M I  +P
Sbjct: 435 W--DMRNKQFHTGIEIKVWAIACF-APQRQCTEV--HLKSFTEQLRKISRDAGMPIQGQP 489

Query: 543 AEMIEVDGDANSYIDTLR--KYTRPTLQMGMSCLLVFKVICILPNDDKRRYDSIKRYLCT 600
                  G A+S     R  K T   LQ+         V+ ILP      Y  +KR   T
Sbjct: 490 CFCKYAQG-ADSVEPMFRHLKNTYAGLQL---------VVVILPGKTPV-YAEVKRVGDT 538

Query: 601 KCPIPSQCVVKKTLEKVQARTIVTKIAQQMNCKMGGA------LWKVETDVQRTMFVGID 654
              + +QCV  K +++   +T+ + +  ++N K+GG         +     Q  +F+G D
Sbjct: 539 VLGMATQCVQMKNVQRTTPQTL-SNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGAD 597

Query: 655 CFHDIVN--RQKSIAGFVASTNAELTKWYSQCVIQKTGEELVKELEICLKAALDVWCKNE 712
             H      ++ SIA  V S +A   ++ +   +Q+  +E++++L   ++  L  + K+ 
Sbjct: 598 VTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKST 657

Query: 713 SSMPHSVIVYRDGVGDGQLQALLDHEAKKM-STYLKTISPNNFTLAFIVVKKRINTRFFL 771
              P  +I YRDGV +GQ Q +L HE   +    +K        + FIVV+KR +TR F 
Sbjct: 658 RFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFC 717

Query: 772 ----KHGSNFQNPPPGTVIDVELTRNEWYDFFIVSQSVQDGTVTPTHYNVIYDTIGLSPD 827
               +      N P GT +D ++T    +DF++ S +   GT  P+HY+V++D    S D
Sbjct: 718 TDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSD 777

Query: 828 TVQRLTYCLCHMYYNLPGIIRVPAPCHYAHKLAY 861
            +Q LTY LCH Y      + +PAP +YAH +A+
Sbjct: 778 ELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAF 811


>gi|6912352 eukaryotic translation initiation factor 2C, 1 [Homo
           sapiens]
          Length = 857

 Score =  147 bits (372), Expect = 3e-35
 Identities = 188/816 (23%), Positives = 352/816 (43%), Gaps = 109/816 (13%)

Query: 119 GSEGTVVQLLANHFRVISRPQWVAYKYNVDYKPDIEDGNLRTILLD---QHRRK--FGER 173
           G+ G  ++LLAN+F V   P+   Y Y VD KPD     +   +++   QH +   FG+R
Sbjct: 30  GTVGKPIKLLANYFEV-DIPKIDVYHYEVDIKPDKCPRRVNREVVEYMVQHFKPQIFGDR 88

Query: 174 H-IFDGNS---LLLSRPLKERRVEWLSTT----KDKNIVKITVEFSKELT---------- 215
             ++DG      + + P+   RV++  T     KD+ I K+++++   ++          
Sbjct: 89  KPVYDGKKNIYTVTALPIGNERVDFEVTIPGEGKDR-IFKVSIKWLAIVSWRMLHEALVS 147

Query: 216 ---PTSPDCLRYYNILFRRTFKLLDFEQVGRNYYTKKKAIQLYRH--GTSLEIWLGYVTS 270
              P   + ++  ++  R    +  +  VGR++++  +    Y H  G   E+W G+  S
Sbjct: 148 GQIPVPLESVQALDVAMRHLASMR-YTPVGRSFFSPPEG---YYHPLGGGREVWFGFHQS 203

Query: 271 VLQYENSITLCADVSHKLL-RIETAYDF------IKRTSAQAQ--TGNIREEVTNKLIGS 321
           V      + L  DVS     + +   +F      I+    Q +  T + R   T ++ G 
Sbjct: 204 VRPAMWKMMLNIDVSATAFYKAQPVIEFMCEVLDIRNIDEQPKPLTDSQRVRFTKEIKGL 263

Query: 322 IVLTKY---NNKTYRVDDIDWKQNPEDTF----NKSDGSKITYIDYYRQQHKEIVTVKKQ 374
            V   +     + YRV ++  +     TF          + T   Y++Q++   +     
Sbjct: 264 KVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLESGQTVECTVAQYFKQKYNLQLKYPHL 323

Query: 375 PLLVSQGRWKKGLTGTQREPILLIPQLCHMTG-------LTDEICKDYSIVKELAKHTRL 427
           P L           G +++   L  ++C++         LTD   +  +++K  A   R 
Sbjct: 324 PCLQ---------VGQEQKHTYLPLEVCNIVAGQRCIKKLTDN--QTSTMIKATA---RS 369

Query: 428 SPRRRHHTLKEFINTLQDNKKVR--ELLQLWDLKFDTNFLSVPGRVLKNANIVQG--RRM 483
           +P R+     E I+ L  N        +Q + +K   +   V GRVL    +  G   R 
Sbjct: 370 APDRQ-----EEISRLMKNASYNLDPYIQEFGIKVKDDMTEVTGRVLPAPILQYGGRNRA 424

Query: 484 VKANSQGDWSREIRELPLLNAMPLHSWLILY---SRSSHREAM-SLKGHLQSVTAPMGIT 539
           +   +QG W  ++R     N + +  W I      +    E + +    L+ ++   G+ 
Sbjct: 425 IATPNQGVW--DMRGKQFYNGIEIKVWAIACFAPQKQCREEVLKNFTDQLRKISKDAGMP 482

Query: 540 MKPAEMIEVDGDANSYIDTLRKYTRPTLQMGMSCLLVFKVICILPNDDKRRYDSIKRYLC 599
           ++              ++ + ++ + T   G+  ++V     ILP      Y  +KR   
Sbjct: 483 IQGQPCFCKYAQGADSVEPMFRHLKNTYS-GLQLIIV-----ILPGKTPV-YAEVKRVGD 535

Query: 600 TKCPIPSQCVVKKTLEKVQARTIVTKIAQQMNCKMGGALWKVETDVQRT-------MFVG 652
           T   + +QCV  K + K   +T+ + +  ++N K+GG +  +    QR+       +F+G
Sbjct: 536 TLLGMATQCVQVKNVVKTSPQTL-SNLCLKINVKLGG-INNILVPHQRSAVFQQPVIFLG 593

Query: 653 IDCFHDIVN--RQKSIAGFVASTNAELTKWYSQCVIQKTGEELVKELEICLKAALDVWCK 710
            D  H      ++ SI   V S +A  +++ +   +Q+  +E++++L   ++  L  + K
Sbjct: 594 ADVTHPPAGDGKKPSITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSYMVRELLIQFYK 653

Query: 711 NESSMPHSVIVYRDGVGDGQLQALLDHEAKKM-STYLKTISPNNFTLAFIVVKKRINTRF 769
           +    P  +I YRDGV +GQL  +L +E   +    +K        + +IVV+KR +TR 
Sbjct: 654 STRFKPTRIIFYRDGVPEGQLPQILHYELLAIRDACIKLEKDYQPGITYIVVQKRHHTRL 713

Query: 770 FLKHGSN----FQNPPPGTVIDVELTRNEWYDFFIVSQSVQDGTVTPTHYNVIYDTIGLS 825
           F    +       N P GT +D  +T    +DF++ S +   GT  P+HY V++D    +
Sbjct: 714 FCADKNERIGKSGNIPAGTTVDTNITHPFEFDFYLCSHAGIQGTSRPSHYYVLWDDNRFT 773

Query: 826 PDTVQRLTYCLCHMYYNLPGIIRVPAPCHYAHKLAY 861
            D +Q LTY LCH Y      + +PAP +YA  +A+
Sbjct: 774 ADELQILTYQLCHTYVRCTRSVSIPAPAYYARLVAF 809


>gi|29294647 eukaryotic translation initiation factor 2C, 3 isoform
           a [Homo sapiens]
          Length = 860

 Score =  144 bits (363), Expect = 4e-34
 Identities = 190/824 (23%), Positives = 342/824 (41%), Gaps = 116/824 (14%)

Query: 119 GSEGTVVQLLANHFRVISRPQWVAYKYNVDYKPDIEDGNLRTILLD---QHRRK--FGER 173
           G+ G  ++LLAN F+V   P+   Y Y VD KPD     +   ++D   QH +   FG+R
Sbjct: 24  GTMGKPIKLLANCFQV-EIPKIDVYLYEVDIKPDKCPRRVNREVVDSMVQHFKVTIFGDR 82

Query: 174 H-IFDGN-SLLLSRPL------------------KER----------RVEW--LSTTKDK 201
             ++DG  SL  + PL                  K+R          RV W  L      
Sbjct: 83  RPVYDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRPFKVSIKFVSRVSWHLLHEVLTG 142

Query: 202 NIVKITVEFSKELTPTSPDCLRYYNILFRRTFKLLDFEQVGRNYYTKKKAIQLYRH--GT 259
             +   +E  K   P S + +   +++ R     + +  VGR++++  +    Y H  G 
Sbjct: 143 RTLPEPLELDK---PISTNPVHAVDVVLRH-LPSMKYTPVGRSFFSAPEG---YDHPLGG 195

Query: 260 SLEIWLGYVTSVLQYENSITLCADVSHKLL-RIETAYDFIKRT--------SAQAQTGNI 310
             E+W G+  SV      + L  DVS     + +    F+             +  T + 
Sbjct: 196 GREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQFMCEVLDIHNIDEQPRPLTDSH 255

Query: 311 REEVTNKLIGSIVLTKY---NNKTYRVDDIDWKQNPEDTF--NKSDGSKI--TYIDYYRQ 363
           R + T ++ G  V   +     + YRV ++  +     TF     +G  +  T   Y+R+
Sbjct: 256 RVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLENGQTVERTVAQYFRE 315

Query: 364 QHKEIVTVKKQPLLVSQGRWKKGLTGTQREPILLIPQLCHMTG-------LTDEICKDYS 416
           ++   +     P L           G +++   L  ++C++         LTD      +
Sbjct: 316 KYTLQLKYPHLPCLQ---------VGQEQKHTYLPLEVCNIVAGQRCIKKLTD------N 360

Query: 417 IVKELAKHTRLSPRRRHHTLKEFINTLQDNKKVRELLQLWDLKFDTNFLSVPGRVLKNAN 476
               + K T  S   R   +   + +   N +    +Q +  K       V GRVL    
Sbjct: 361 QTSTMIKATARSAPDRQEEISRLVRSA--NYETDPFVQEFQFKVRDEMAHVTGRVLPAPM 418

Query: 477 IVQG--RRMVKANSQGDWSREIRELPLLNAMPLHSWLIL-YSRSSHREAMSLKG---HLQ 530
           +  G   R V   S G W  ++R       + +  W I  ++         LKG    L+
Sbjct: 419 LQYGGRNRTVATPSHGVW--DMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLR 476

Query: 531 SVTAPMGITMKPAEMIEVDGDANSYIDTLRKYTRPTLQMGMSCLLVFKVICILPNDDKRR 590
            ++   G+ ++              ++ + ++ + T   G+  ++V     ILP      
Sbjct: 477 KISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYS-GLQLIIV-----ILPGKTPV- 529

Query: 591 YDSIKRYLCTKCPIPSQCVVKKTLEKVQARTIVTKIAQQMNCKMGGAL------WKVETD 644
           Y  +KR   T   + +QCV  K + K   +T+ + +  ++N K+GG         +    
Sbjct: 530 YAEVKRVGDTLLGMATQCVQVKNVIKTSPQTL-SNLCLKINVKLGGINNILVPHQRPSVF 588

Query: 645 VQRTMFVGIDCFHDIVN--RQKSIAGFVASTNAELTKWYSQCVIQKTGEELVKELEICLK 702
            Q  +F+G D  H      ++ SIA  V S +A  +++ +   +Q+  +E++++L   ++
Sbjct: 589 QQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVR 648

Query: 703 AALDVWCKNESSMPHSVIVYRDGVGDGQLQALLDHEAKKMSTYLKTISPNNFT-LAFIVV 761
             L  + K+    P  +I YRDGV +GQ + +L +E   +     ++  +    + +IVV
Sbjct: 649 ELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVV 708

Query: 762 KKRINTRFFL----KHGSNFQNPPPGTVIDVELTRNEWYDFFIVSQSVQDGTVTPTHYNV 817
           +KR +TR F     +      N P GT +D ++T    +DF++ S +   GT  P+HY+V
Sbjct: 709 QKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHV 768

Query: 818 IYDTIGLSPDTVQRLTYCLCHMYYNLPGIIRVPAPCHYAHKLAY 861
           ++D    + D +Q LTY LCH Y      + +PAP +YAH +A+
Sbjct: 769 LWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAF 812


>gi|29029593 eukaryotic translation initiation factor 2C, 4 [Homo
           sapiens]
          Length = 861

 Score =  135 bits (339), Expect = 2e-31
 Identities = 182/826 (22%), Positives = 345/826 (41%), Gaps = 117/826 (14%)

Query: 119 GSEGTVVQLLANHFRVISRPQWVAYKYNVDYKPDIEDGNLRTILLDQHRRKF-------- 170
           G+ G  ++LLANHF+V   P+   Y Y+VD KP+     +   ++D   R F        
Sbjct: 22  GTVGKPIRLLANHFQV-QIPKIDVYHYDVDIKPEKRPRRVNREVVDTMVRHFKMQIFGDR 80

Query: 171 -----GERHIFDGNSLLLSRPLKERRVEWLSTTKDKNIVKITVEF-------------SK 212
                G+R+++  + L + R   +  V      KD+   K++V++             + 
Sbjct: 81  QPGYDGKRNMYTAHPLPIGRDRVDMEVTLPGEGKDQTF-KVSVQWVSVVSLQLLLEALAG 139

Query: 213 ELTPTSPDCLRYYNILFRRTFKLLDFEQVGRNYYTKKKAIQLYRH--GTSLEIWLGYVTS 270
            L     D ++  +++ R     + +  VGR++++  +    Y H  G   E+W G+  S
Sbjct: 140 HLNEVPDDSVQALDVITRH-LPSMRYTPVGRSFFSPPEG---YYHPLGGGREVWFGFHQS 195

Query: 271 VLQYENSITLCADVSHKLL-RIETAYDF------IKRTSAQAQ--TGNIREEVTNKLIGS 321
           V     ++ L  DVS     R +   +F      I+  + Q +  T + R + T ++ G 
Sbjct: 196 VRPAMWNMMLNIDVSATAFYRAQPIIEFMCEVLDIQNINEQTKPLTDSQRVKFTKEIRGL 255

Query: 322 IVLTKY---NNKTYRVDDIDWKQNPEDTF----NKSDGSKITYIDYYRQQHKEIVTVKKQ 374
            V   +     + YRV ++  +     TF          + T   Y++Q++   +     
Sbjct: 256 KVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLENGQAMECTVAQYFKQKYSLQLKYPHL 315

Query: 375 PLLVSQGRWKKGLTGTQREPILLIPQLCHMTG-------LTDEICKDYSIVKELAKHTRL 427
           P L           G +++   L  ++C++         LTD   +  +++K  A   R 
Sbjct: 316 PCLQ---------VGQEQKHTYLPLEVCNIVAGQRCIKKLTDN--QTSTMIKATA---RS 361

Query: 428 SPRRRHHTLKEFINTLQDNKKVR---ELLQLWDLKFDTNFLSVPGRVLKNANIVQGRR-- 482
           +P R+    +E    ++ N  V      L+ + +        + GRVL    +  G R  
Sbjct: 362 APDRQ----EEISRLVKSNSMVGGPDPYLKEFGIVVHNEMTELTGRVLPAPMLQYGGRNK 417

Query: 483 MVKANSQGDWSREIRELPLLNAMPLHSWLI--LYSRSSHREAM--SLKGHLQSVTAPMGI 538
            V   +QG W  ++R       + +  W +     +   RE +  S    L+ ++   G+
Sbjct: 418 TVATPNQGVW--DMRGKQFYAGIEIKVWAVACFAPQKQCREDLLKSFTDQLRKISKDAGM 475

Query: 539 TMKPAEMIEVDGDANSYIDTLRKYTRPTLQMGMSCLLVFKVICILPNDDKRRYDSIKRYL 598
            ++              ++ + K+ + T  +G+  ++V     ILP      Y  +KR  
Sbjct: 476 PIQGQPCFCKYAQGADSVEPMFKHLKMTY-VGLQLIVV-----ILPGKTPV-YAEVKRVG 528

Query: 599 CTKCPIPSQCVVKKTLEKVQARTIVTKIAQQMNCKMGGAL------WKVETDVQRTMFVG 652
            T   + +QCV  K + K   +T+ + +  ++N K+GG         +     Q  +F+G
Sbjct: 529 DTLLGMATQCVQVKNVVKTSPQTL-SNLCLKINAKLGGINNVLVPHQRPSVFQQPVIFLG 587

Query: 653 IDCFHDIVN--RQKSIAGFVASTNAELTKWYSQCVIQKTGEELVKELEICLKAALDV--- 707
            D  H      ++ SIA  V S +   +++ +   +Q + +E+ +EL    +   D+   
Sbjct: 588 ADVTHPPAGDGKKPSIAAVVGSMDGHPSRYCATVRVQTSRQEISQELLYSQEVIQDLTNM 647

Query: 708 -------WCKNESSMPHSVIVYRDGVGDGQLQALLDHEAKKMSTYLKTISPNNFT-LAFI 759
                  + K+    P  +I YR GV +GQ++ +   E   +     ++  +    + +I
Sbjct: 648 VRELLIQFYKSTRFKPTRIIYYRGGVSEGQMKQVAWPELIAIRKACISLEEDYRPGITYI 707

Query: 760 VVKKRINTRFFL----KHGSNFQNPPPGTVIDVELTRNEWYDFFIVSQSVQDGTVTPTHY 815
           VV+KR +TR F     +      N P GT +D  +T    +DF++ S +   GT  P+HY
Sbjct: 708 VVQKRHHTRLFCADKTERVGKSGNVPAGTTVDSTITHPSEFDFYLCSHAGIQGTSRPSHY 767

Query: 816 NVIYDTIGLSPDTVQRLTYCLCHMYYNLPGIIRVPAPCHYAHKLAY 861
            V++D    + D +Q LTY LCH Y      + +PAP +YA  +A+
Sbjct: 768 QVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYARLVAF 813


>gi|29337286 eukaryotic translation initiation factor 2C, 3 isoform
           b [Homo sapiens]
          Length = 626

 Score =  129 bits (324), Expect = 1e-29
 Identities = 113/460 (24%), Positives = 206/460 (44%), Gaps = 31/460 (6%)

Query: 421 LAKHTRLSPRRRHHTLKEFINTLQDNKKVRELLQLWDLKFDTNFLSVPGRVLKNANIVQG 480
           + K T  S   R   +   + +   N +    +Q +  K       V GRVL    +  G
Sbjct: 131 MIKATARSAPDRQEEISRLVRSA--NYETDPFVQEFQFKVRDEMAHVTGRVLPAPMLQYG 188

Query: 481 --RRMVKANSQGDWSREIRELPLLNAMPLHSWLIL-YSRSSHREAMSLKG---HLQSVTA 534
              R V   S G W  ++R       + +  W I  ++         LKG    L+ ++ 
Sbjct: 189 GRNRTVATPSHGVW--DMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISK 246

Query: 535 PMGITMKPAEMIEVDGDANSYIDTLRKYTRPTLQMGMSCLLVFKVICILPNDDKRRYDSI 594
             G+ ++              ++ + ++ + T   G+  ++V     ILP      Y  +
Sbjct: 247 DAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYS-GLQLIIV-----ILPGKTPV-YAEV 299

Query: 595 KRYLCTKCPIPSQCVVKKTLEKVQARTIVTKIAQQMNCKMGGAL------WKVETDVQRT 648
           KR   T   + +QCV  K + K   +T+ + +  ++N K+GG         +     Q  
Sbjct: 300 KRVGDTLLGMATQCVQVKNVIKTSPQTL-SNLCLKINVKLGGINNILVPHQRPSVFQQPV 358

Query: 649 MFVGIDCFHDIVN--RQKSIAGFVASTNAELTKWYSQCVIQKTGEELVKELEICLKAALD 706
           +F+G D  H      ++ SIA  V S +A  +++ +   +Q+  +E++++L   ++  L 
Sbjct: 359 IFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLI 418

Query: 707 VWCKNESSMPHSVIVYRDGVGDGQLQALLDHEAKKMSTYLKTISPNNFT-LAFIVVKKRI 765
            + K+    P  +I YRDGV +GQ + +L +E   +     ++  +    + +IVV+KR 
Sbjct: 419 QFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRH 478

Query: 766 NTRFFL----KHGSNFQNPPPGTVIDVELTRNEWYDFFIVSQSVQDGTVTPTHYNVIYDT 821
           +TR F     +      N P GT +D ++T    +DF++ S +   GT  P+HY+V++D 
Sbjct: 479 HTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDD 538

Query: 822 IGLSPDTVQRLTYCLCHMYYNLPGIIRVPAPCHYAHKLAY 861
              + D +Q LTY LCH Y      + +PAP +YAH +A+
Sbjct: 539 NCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAF 578


>gi|239750966 PREDICTED: hypothetical protein XP_002347633 [Homo
           sapiens]
          Length = 261

 Score = 37.7 bits (86), Expect = 0.047
 Identities = 25/75 (33%), Positives = 32/75 (42%), Gaps = 6/75 (8%)

Query: 2   PGRARTRARGRARRRESYQQEAPG------GPRAPGSATTQEPPQLQSTPRPLQEEVPVV 55
           PG AR   RGRA R  +      G      GP +P +A T  PP   + P P  E +   
Sbjct: 183 PGSARRPRRGRAGRGGAAPAPPTGSMRAGPGPSSPSAAPTSHPPPSPACPGPEMETILRN 242

Query: 56  RPLQPRAARGGAGGG 70
            P +   A  G+G G
Sbjct: 243 PPARSPGAGWGSGAG 257


>gi|239745372 PREDICTED: hypothetical protein XP_002343483 [Homo
           sapiens]
          Length = 261

 Score = 37.7 bits (86), Expect = 0.047
 Identities = 25/75 (33%), Positives = 32/75 (42%), Gaps = 6/75 (8%)

Query: 2   PGRARTRARGRARRRESYQQEAPG------GPRAPGSATTQEPPQLQSTPRPLQEEVPVV 55
           PG AR   RGRA R  +      G      GP +P +A T  PP   + P P  E +   
Sbjct: 183 PGSARRPRRGRAGRGGAAPAPPTGSMRAGPGPSSPSAAPTSHPPPSPACPGPEMETILRN 242

Query: 56  RPLQPRAARGGAGGG 70
            P +   A  G+G G
Sbjct: 243 PPARSPGAGWGSGAG 257


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 36.6 bits (83), Expect = 0.11
 Identities = 31/88 (35%), Positives = 35/88 (39%), Gaps = 7/88 (7%)

Query: 6   RTRARGRARRRESYQQEAPGGPR-APGSATTQEPPQLQSTPRPLQEEVPVVRPLQPRAAR 64
           R  AR +  RR +     P  PR AP +A    PP    TP P     PV      RA R
Sbjct: 94  RNAARVQPPRRGATPPAPPRAPRGAPAAAAAAAPPP---TPAPPPPPAPVAAAAPARAPR 150

Query: 65  GGAGGGAQ--SQGVKEPGPEAGLHTAPL 90
             A       S G  +PGP A    APL
Sbjct: 151 AAAAAATAPPSPGPAQPGPRA-QRAAPL 177


>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
          Length = 1094

 Score = 35.4 bits (80), Expect = 0.23
 Identities = 26/83 (31%), Positives = 36/83 (43%), Gaps = 19/83 (22%)

Query: 20  QQEAPGGPRAPGSATTQEPPQLQSTPRPLQEEVPVVRPLQPRAARGGAGGGAQ-SQGVKE 78
           ++EAPG PRAPG+      P +   P                  RG +G GA+ S    E
Sbjct: 238 EREAPGTPRAPGARDAVRIPTVDGRP------------------RGTSGMGARVSLQALE 279

Query: 79  PGPEAGLHTAPLQERRIGGVFQD 101
              EAG  T  + +R I  V++D
Sbjct: 280 AEAEAGAETEAMLQRHIDRVYRD 302


>gi|50843837 hypothetical protein LOC55701 [Homo sapiens]
          Length = 1519

 Score = 35.4 bits (80), Expect = 0.23
 Identities = 28/97 (28%), Positives = 40/97 (41%), Gaps = 22/97 (22%)

Query: 1   MPGRARTRARGRARRRESYQQEAPGGPRA------PGS-----ATTQEPPQLQSTPRPLQ 49
           +P R     +GR RR  ++  +   GPR       PG      A+ + PP  ++ P    
Sbjct: 271 VPTRKGAGGKGRHRRHRAWMHQKGLGPRGQDGARPPGEGSSTGASPESPPGAEAVPEAAV 330

Query: 50  EEV--PVVR---------PLQPRAARGGAGGGAQSQG 75
            EV  P            PL+P   RGG GGG  ++G
Sbjct: 331 LEVSEPPAEAVGEASGSCPLRPGELRGGGGGGQGAEG 367


>gi|223633935 hypothetical protein LOC254427 [Homo sapiens]
          Length = 435

 Score = 35.0 bits (79), Expect = 0.31
 Identities = 31/97 (31%), Positives = 42/97 (43%), Gaps = 7/97 (7%)

Query: 7   TRARGRARRRESYQQ---EAPGGPRAPGSATTQEPPQLQSTPRPLQEEVPVVRP--LQPR 61
           T+A G A   + +++   E P  P  P   T   PP L STP P + E+    P    PR
Sbjct: 127 TQAAGPAPAGKEHRKQDAETPPPPDPPAPETLLAPPPLPSTPDPPRRELRAPSPPVEHPR 186

Query: 62  AARGGAGGGAQSQGVKE--PGPEAGLHTAPLQERRIG 96
             R        +Q + E   G EA   T+P +E R G
Sbjct: 187 LLRSVPTPLVMAQKISERMAGNEALSPTSPFREGRPG 223


>gi|51173735 ras responsive element binding protein 1 isoform 2 [Homo
            sapiens]
          Length = 1687

 Score = 35.0 bits (79), Expect = 0.31
 Identities = 22/73 (30%), Positives = 36/73 (49%), Gaps = 5/73 (6%)

Query: 13   ARRRESYQQEAPGGPRAPGSATTQEPPQLQSTPRPLQEEVPVVRPLQPRAARGGAG-GGA 71
            +R R+++ ++ P   +  G++T +E PQ    P P QEE P   P +   +  GAG   A
Sbjct: 1409 SRHRKAHGRQEPKDEKGDGASTAEEGPQ----PAPEQEEKPPETPAEVVESAPGAGEAPA 1464

Query: 72   QSQGVKEPGPEAG 84
            +    +  GP  G
Sbjct: 1465 EKLAEETEGPSDG 1477


>gi|51173737 ras responsive element binding protein 1 isoform 1 [Homo
            sapiens]
          Length = 1742

 Score = 35.0 bits (79), Expect = 0.31
 Identities = 22/73 (30%), Positives = 36/73 (49%), Gaps = 5/73 (6%)

Query: 13   ARRRESYQQEAPGGPRAPGSATTQEPPQLQSTPRPLQEEVPVVRPLQPRAARGGAG-GGA 71
            +R R+++ ++ P   +  G++T +E PQ    P P QEE P   P +   +  GAG   A
Sbjct: 1464 SRHRKAHGRQEPKDEKGDGASTAEEGPQ----PAPEQEEKPPETPAEVVESAPGAGEAPA 1519

Query: 72   QSQGVKEPGPEAG 84
            +    +  GP  G
Sbjct: 1520 EKLAEETEGPSDG 1532


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 35.0 bits (79), Expect = 0.31
 Identities = 24/96 (25%), Positives = 37/96 (38%), Gaps = 2/96 (2%)

Query: 2   PGRARTRARGRARRRESYQQEAPGGPRAPGSATTQEPPQLQSTPRPLQEEVPVVRPLQPR 61
           P   R R R R+R R    +  P   R P       P ++   PR  +   PV R  +  
Sbjct: 293 PSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSS 352

Query: 62  AARGGAGGGAQSQGVKEP--GPEAGLHTAPLQERRI 95
           A+  G+   + S   + P   P     + P + RR+
Sbjct: 353 ASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRL 388


>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
          Length = 2217

 Score = 34.7 bits (78), Expect = 0.40
 Identities = 35/122 (28%), Positives = 50/122 (40%), Gaps = 28/122 (22%)

Query: 17  ESYQQEAPG--GPRAPGSATTQEPPQ--------LQSTPRPLQEEV--------PVVRPL 58
           ES Q+E PG     APG     +PPQ        L  T R + E          P     
Sbjct: 48  ESDQEEPPGLEAAEAPGP----QPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVA 103

Query: 59  QPRAARGGAGGGAQSQGVKEPGPE---AGLHTAPLQERRIGGVFQDLVVNTRQDMKHVKD 115
           QP A    A  G +  G +EPGP+   A + TAP  +   GG  ++     R++ +   +
Sbjct: 104 QPGAPGAPADAGPEPVGTQEPGPDPIAAAVETAPAPD---GGPREEAAATVRKEDEGAAE 160

Query: 116 SK 117
           +K
Sbjct: 161 AK 162


>gi|18079216 CASK interacting protein 1 [Homo sapiens]
          Length = 1431

 Score = 34.3 bits (77), Expect = 0.52
 Identities = 23/72 (31%), Positives = 32/72 (44%), Gaps = 6/72 (8%)

Query: 27   PRAPGSATTQEPPQLQSTPRPLQEEVPVVRPLQPRAARGGAGGGAQSQGVKEPGPEAGLH 86
            P +P    TQ  P+LQ +P P  ++VP+  P  P   R  A G       K P P     
Sbjct: 1225 PVSPKPVLTQPVPKLQGSPTPTSKKVPLPGPGSPEVKR--AHGTPPPVSPKPPPPP---- 1278

Query: 87   TAPLQERRIGGV 98
            TAP   + + G+
Sbjct: 1279 TAPKPVKAVAGL 1290


>gi|239746530 PREDICTED: hypothetical protein XP_002343754 [Homo
           sapiens]
          Length = 536

 Score = 34.3 bits (77), Expect = 0.52
 Identities = 28/80 (35%), Positives = 32/80 (40%), Gaps = 6/80 (7%)

Query: 2   PGRARTRARGRARRRESYQQEAPGGPRAPGSATTQEPPQLQSTPRPLQEEVPVVRPLQPR 61
           P R   R   R  R    Q   PGG RAPG      P      P P ++    VRPL   
Sbjct: 171 PSRCLGRLEPRRWRGHGLQ---PGGARAPGLQVPAPPGPASPAPLPARQPHKGVRPL--G 225

Query: 62  AARGG-AGGGAQSQGVKEPG 80
             RGG A    Q +G+  PG
Sbjct: 226 CCRGGRAQAAGQPRGLCLPG 245


>gi|239751186 PREDICTED: WD repeat domain 81 [Homo sapiens]
          Length = 2240

 Score = 33.9 bits (76), Expect = 0.68
 Identities = 30/112 (26%), Positives = 42/112 (37%), Gaps = 7/112 (6%)

Query: 2   PGRARTRARGRARRRESYQQEAPGGPRAPGSATTQEPPQLQSTPRPLQEEVPVVRPLQPR 61
           PG    R   RA R    ++  P    AP        P+   TP  +      V  L P 
Sbjct: 234 PGAQDPRRGKRAPRPPLRRRRLPAAASAPAPVPRPSQPRRPGTPEAVASR--AVAGLSPA 291

Query: 62  AARGGAGGGAQSQGVKEPG---PEAGLHTAPLQERR--IGGVFQDLVVNTRQ 108
              GG    AQ  G +E     P  G H+ P  + +  +  V +DL ++ RQ
Sbjct: 292 LPPGGLEEMAQGSGGREGALRTPAGGWHSPPSPDMQELLRSVERDLSIDPRQ 343


>gi|239749150 PREDICTED: hypothetical protein XP_002346928 [Homo
          sapiens]
          Length = 229

 Score = 33.9 bits (76), Expect = 0.68
 Identities = 22/60 (36%), Positives = 28/60 (46%), Gaps = 1/60 (1%)

Query: 28 RAPGSATTQEPPQLQSTPRPLQEEVPVVRPLQPRAARGGAGGGAQSQGVKEPGPEAGLHT 87
          R  G  +T+E    +   +P   EV   R    RA  GGAGG  Q+ GV E G + G  T
Sbjct: 16 RQSGDRSTREAGMKEPPLQPKAPEVTFARRAL-RACAGGAGGAGQAGGVCEAGADWGAQT 74


>gi|19924103 synapsin II isoform IIa [Homo sapiens]
          Length = 582

 Score = 33.9 bits (76), Expect = 0.68
 Identities = 26/78 (33%), Positives = 34/78 (43%), Gaps = 4/78 (5%)

Query: 15  RRESYQQEAPGGPRAPGSATTQE-PPQLQSTP--RPLQEEVPVVRPLQPRAARGGAGGGA 71
           +R   QQ  P  P  PG+A+    PP     P  RP     P  +P  P  + G +   +
Sbjct: 27  QRPEPQQPPPPPPPGPGAASASAAPPTASPGPERRPPPASAPAPQPA-PTPSVGSSFFSS 85

Query: 72  QSQGVKEPGPEAGLHTAP 89
            SQ VK+    AGL  AP
Sbjct: 86  LSQAVKQTAASAGLVDAP 103


>gi|193082982 zinc finger protein 837 isoform 1 [Homo sapiens]
          Length = 531

 Score = 33.9 bits (76), Expect = 0.68
 Identities = 22/71 (30%), Positives = 29/71 (40%), Gaps = 1/71 (1%)

Query: 20 QQEAPGG-PRAPGSATTQEPPQLQSTPRPLQEEVPVVRPLQPRAARGGAGGGAQSQGVKE 78
          Q+   GG P+A     +    +    PRPL+E+    RP Q    RG AGG     G   
Sbjct: 6  QKAGQGGLPKADAQGASGAREKRPEEPRPLEEDRAGSRPTQKGDLRGAAGGRTTPPGGGS 65

Query: 79 PGPEAGLHTAP 89
           G   G+   P
Sbjct: 66 RGCSLGVSPGP 76


>gi|193082980 zinc finger protein 837 isoform 2 [Homo sapiens]
          Length = 531

 Score = 33.9 bits (76), Expect = 0.68
 Identities = 22/71 (30%), Positives = 29/71 (40%), Gaps = 1/71 (1%)

Query: 20 QQEAPGG-PRAPGSATTQEPPQLQSTPRPLQEEVPVVRPLQPRAARGGAGGGAQSQGVKE 78
          Q+   GG P+A     +    +    PRPL+E+    RP Q    RG AGG     G   
Sbjct: 6  QKAGQGGLPKADAQGASGAREKRPEEPRPLEEDRAGSRPTQKGDLRGAAGGRTTPPGGGS 65

Query: 79 PGPEAGLHTAP 89
           G   G+   P
Sbjct: 66 RGCSLGVSPGP 76


>gi|19924101 synapsin II isoform IIb [Homo sapiens]
          Length = 478

 Score = 33.9 bits (76), Expect = 0.68
 Identities = 26/78 (33%), Positives = 34/78 (43%), Gaps = 4/78 (5%)

Query: 15  RRESYQQEAPGGPRAPGSATTQE-PPQLQSTP--RPLQEEVPVVRPLQPRAARGGAGGGA 71
           +R   QQ  P  P  PG+A+    PP     P  RP     P  +P  P  + G +   +
Sbjct: 27  QRPEPQQPPPPPPPGPGAASASAAPPTASPGPERRPPPASAPAPQPA-PTPSVGSSFFSS 85

Query: 72  QSQGVKEPGPEAGLHTAP 89
            SQ VK+    AGL  AP
Sbjct: 86  LSQAVKQTAASAGLVDAP 103


>gi|238908524 hypothetical protein LOC389333 [Homo sapiens]
          Length = 1015

 Score = 33.5 bits (75), Expect = 0.89
 Identities = 29/91 (31%), Positives = 36/91 (39%), Gaps = 10/91 (10%)

Query: 3   GRARTRARGRARRRESYQQEAPGGPRAPGSATTQEPPQLQSTPRPLQEEVPVVRPLQPRA 62
           G  RT   G AR         P G R+P   +    PQ+Q++P P     P   P  P  
Sbjct: 772 GDGRTSPLGGARSSSQRSPVGPAGVRSPRPGS----PQMQASPSPGIAPKPKTPPTAPEP 827

Query: 63  ARGGAGGGAQSQGVKEPGPEAGLHTAPLQER 93
           A        Q+   +EP   AG  TAP Q R
Sbjct: 828 A-----AAVQAPLPREPLALAG-RTAPAQPR 852



 Score = 31.6 bits (70), Expect = 3.4
 Identities = 26/81 (32%), Positives = 34/81 (41%), Gaps = 6/81 (7%)

Query: 2   PGR-ARTRARGRARRRESYQQEAPGG--PRAPGSATTQEPPQLQSTPRPLQEEVPVVRPL 58
           PGR A  + R     + S Q+  PG   PR PGS      PQL++ P     E+ V+  +
Sbjct: 61  PGRGAGAQPRLSVSAQNSRQRHGPGSGFPRGPGSGPRPPQPQLRTLP---SGEMEVIFGV 117

Query: 59  QPRAARGGAGGGAQSQGVKEP 79
            P     GA      Q   EP
Sbjct: 118 GPLFGCSGADDREAQQQFTEP 138


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.135    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,044,892
Number of Sequences: 37866
Number of extensions: 1662376
Number of successful extensions: 7205
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 34
Number of HSP's successfully gapped in prelim test: 126
Number of HSP's that attempted gapping in prelim test: 6938
Number of HSP's gapped (non-prelim): 328
length of query: 882
length of database: 18,247,518
effective HSP length: 111
effective length of query: 771
effective length of database: 14,044,392
effective search space: 10828226232
effective search space used: 10828226232
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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