BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|153792298 piwi-like 3 [Homo sapiens] (882 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|153792298 piwi-like 3 [Homo sapiens] 1793 0.0 gi|66346725 piwi-like 1 [Homo sapiens] 864 0.0 gi|221316711 piwi-like 4 [Homo sapiens] 637 0.0 gi|209180418 piwi-like 2 [Homo sapiens] 514 e-145 gi|24431985 piwi-like 2 [Homo sapiens] 514 e-145 gi|169217928 PREDICTED: similar to piwi like homolog 2 [Homo sap... 171 4e-42 gi|29171734 eukaryotic translation initiation factor 2C, 2 [Homo... 156 7e-38 gi|6912352 eukaryotic translation initiation factor 2C, 1 [Homo ... 147 3e-35 gi|29294647 eukaryotic translation initiation factor 2C, 3 isofo... 144 4e-34 gi|29029593 eukaryotic translation initiation factor 2C, 4 [Homo... 135 2e-31 gi|29337286 eukaryotic translation initiation factor 2C, 3 isofo... 129 1e-29 gi|239750966 PREDICTED: hypothetical protein XP_002347633 [Homo ... 38 0.047 gi|239745372 PREDICTED: hypothetical protein XP_002343483 [Homo ... 38 0.047 gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 37 0.11 gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 35 0.23 gi|50843837 hypothetical protein LOC55701 [Homo sapiens] 35 0.23 gi|223633935 hypothetical protein LOC254427 [Homo sapiens] 35 0.31 gi|51173735 ras responsive element binding protein 1 isoform 2 [... 35 0.31 gi|51173737 ras responsive element binding protein 1 isoform 1 [... 35 0.31 gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 35 0.31 gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 35 0.40 gi|18079216 CASK interacting protein 1 [Homo sapiens] 34 0.52 gi|239746530 PREDICTED: hypothetical protein XP_002343754 [Homo ... 34 0.52 gi|239751186 PREDICTED: WD repeat domain 81 [Homo sapiens] 34 0.68 gi|239749150 PREDICTED: hypothetical protein XP_002346928 [Homo ... 34 0.68 gi|19924103 synapsin II isoform IIa [Homo sapiens] 34 0.68 gi|193082982 zinc finger protein 837 isoform 1 [Homo sapiens] 34 0.68 gi|193082980 zinc finger protein 837 isoform 2 [Homo sapiens] 34 0.68 gi|19924101 synapsin II isoform IIb [Homo sapiens] 34 0.68 gi|238908524 hypothetical protein LOC389333 [Homo sapiens] 33 0.89 >gi|153792298 piwi-like 3 [Homo sapiens] Length = 882 Score = 1793 bits (4645), Expect = 0.0 Identities = 882/882 (100%), Positives = 882/882 (100%) Query: 1 MPGRARTRARGRARRRESYQQEAPGGPRAPGSATTQEPPQLQSTPRPLQEEVPVVRPLQP 60 MPGRARTRARGRARRRESYQQEAPGGPRAPGSATTQEPPQLQSTPRPLQEEVPVVRPLQP Sbjct: 1 MPGRARTRARGRARRRESYQQEAPGGPRAPGSATTQEPPQLQSTPRPLQEEVPVVRPLQP 60 Query: 61 RAARGGAGGGAQSQGVKEPGPEAGLHTAPLQERRIGGVFQDLVVNTRQDMKHVKDSKTGS 120 RAARGGAGGGAQSQGVKEPGPEAGLHTAPLQERRIGGVFQDLVVNTRQDMKHVKDSKTGS Sbjct: 61 RAARGGAGGGAQSQGVKEPGPEAGLHTAPLQERRIGGVFQDLVVNTRQDMKHVKDSKTGS 120 Query: 121 EGTVVQLLANHFRVISRPQWVAYKYNVDYKPDIEDGNLRTILLDQHRRKFGERHIFDGNS 180 EGTVVQLLANHFRVISRPQWVAYKYNVDYKPDIEDGNLRTILLDQHRRKFGERHIFDGNS Sbjct: 121 EGTVVQLLANHFRVISRPQWVAYKYNVDYKPDIEDGNLRTILLDQHRRKFGERHIFDGNS 180 Query: 181 LLLSRPLKERRVEWLSTTKDKNIVKITVEFSKELTPTSPDCLRYYNILFRRTFKLLDFEQ 240 LLLSRPLKERRVEWLSTTKDKNIVKITVEFSKELTPTSPDCLRYYNILFRRTFKLLDFEQ Sbjct: 181 LLLSRPLKERRVEWLSTTKDKNIVKITVEFSKELTPTSPDCLRYYNILFRRTFKLLDFEQ 240 Query: 241 VGRNYYTKKKAIQLYRHGTSLEIWLGYVTSVLQYENSITLCADVSHKLLRIETAYDFIKR 300 VGRNYYTKKKAIQLYRHGTSLEIWLGYVTSVLQYENSITLCADVSHKLLRIETAYDFIKR Sbjct: 241 VGRNYYTKKKAIQLYRHGTSLEIWLGYVTSVLQYENSITLCADVSHKLLRIETAYDFIKR 300 Query: 301 TSAQAQTGNIREEVTNKLIGSIVLTKYNNKTYRVDDIDWKQNPEDTFNKSDGSKITYIDY 360 TSAQAQTGNIREEVTNKLIGSIVLTKYNNKTYRVDDIDWKQNPEDTFNKSDGSKITYIDY Sbjct: 301 TSAQAQTGNIREEVTNKLIGSIVLTKYNNKTYRVDDIDWKQNPEDTFNKSDGSKITYIDY 360 Query: 361 YRQQHKEIVTVKKQPLLVSQGRWKKGLTGTQREPILLIPQLCHMTGLTDEICKDYSIVKE 420 YRQQHKEIVTVKKQPLLVSQGRWKKGLTGTQREPILLIPQLCHMTGLTDEICKDYSIVKE Sbjct: 361 YRQQHKEIVTVKKQPLLVSQGRWKKGLTGTQREPILLIPQLCHMTGLTDEICKDYSIVKE 420 Query: 421 LAKHTRLSPRRRHHTLKEFINTLQDNKKVRELLQLWDLKFDTNFLSVPGRVLKNANIVQG 480 LAKHTRLSPRRRHHTLKEFINTLQDNKKVRELLQLWDLKFDTNFLSVPGRVLKNANIVQG Sbjct: 421 LAKHTRLSPRRRHHTLKEFINTLQDNKKVRELLQLWDLKFDTNFLSVPGRVLKNANIVQG 480 Query: 481 RRMVKANSQGDWSREIRELPLLNAMPLHSWLILYSRSSHREAMSLKGHLQSVTAPMGITM 540 RRMVKANSQGDWSREIRELPLLNAMPLHSWLILYSRSSHREAMSLKGHLQSVTAPMGITM Sbjct: 481 RRMVKANSQGDWSREIRELPLLNAMPLHSWLILYSRSSHREAMSLKGHLQSVTAPMGITM 540 Query: 541 KPAEMIEVDGDANSYIDTLRKYTRPTLQMGMSCLLVFKVICILPNDDKRRYDSIKRYLCT 600 KPAEMIEVDGDANSYIDTLRKYTRPTLQMGMSCLLVFKVICILPNDDKRRYDSIKRYLCT Sbjct: 541 KPAEMIEVDGDANSYIDTLRKYTRPTLQMGMSCLLVFKVICILPNDDKRRYDSIKRYLCT 600 Query: 601 KCPIPSQCVVKKTLEKVQARTIVTKIAQQMNCKMGGALWKVETDVQRTMFVGIDCFHDIV 660 KCPIPSQCVVKKTLEKVQARTIVTKIAQQMNCKMGGALWKVETDVQRTMFVGIDCFHDIV Sbjct: 601 KCPIPSQCVVKKTLEKVQARTIVTKIAQQMNCKMGGALWKVETDVQRTMFVGIDCFHDIV 660 Query: 661 NRQKSIAGFVASTNAELTKWYSQCVIQKTGEELVKELEICLKAALDVWCKNESSMPHSVI 720 NRQKSIAGFVASTNAELTKWYSQCVIQKTGEELVKELEICLKAALDVWCKNESSMPHSVI Sbjct: 661 NRQKSIAGFVASTNAELTKWYSQCVIQKTGEELVKELEICLKAALDVWCKNESSMPHSVI 720 Query: 721 VYRDGVGDGQLQALLDHEAKKMSTYLKTISPNNFTLAFIVVKKRINTRFFLKHGSNFQNP 780 VYRDGVGDGQLQALLDHEAKKMSTYLKTISPNNFTLAFIVVKKRINTRFFLKHGSNFQNP Sbjct: 721 VYRDGVGDGQLQALLDHEAKKMSTYLKTISPNNFTLAFIVVKKRINTRFFLKHGSNFQNP 780 Query: 781 PPGTVIDVELTRNEWYDFFIVSQSVQDGTVTPTHYNVIYDTIGLSPDTVQRLTYCLCHMY 840 PPGTVIDVELTRNEWYDFFIVSQSVQDGTVTPTHYNVIYDTIGLSPDTVQRLTYCLCHMY Sbjct: 781 PPGTVIDVELTRNEWYDFFIVSQSVQDGTVTPTHYNVIYDTIGLSPDTVQRLTYCLCHMY 840 Query: 841 YNLPGIIRVPAPCHYAHKLAYLVGQSIHQEPNRSLSTRLFYL 882 YNLPGIIRVPAPCHYAHKLAYLVGQSIHQEPNRSLSTRLFYL Sbjct: 841 YNLPGIIRVPAPCHYAHKLAYLVGQSIHQEPNRSLSTRLFYL 882 >gi|66346725 piwi-like 1 [Homo sapiens] Length = 861 Score = 864 bits (2233), Expect = 0.0 Identities = 449/889 (50%), Positives = 598/889 (67%), Gaps = 35/889 (3%) Query: 1 MPGRARTRARGRARRRESYQQEAPGGPRAPGSATTQEPPQLQSTPRPLQEEVPVVRPLQP 60 M GRAR RARGRAR +E+ Q GS +Q+P +Q P+P P L Sbjct: 1 MTGRARARARGRARGQETAQ--------LVGSTASQQPGYIQPRPQP----PPAEGELFG 48 Query: 61 RAA-RGGAGGGAQSQGVKEPGPEAGLHTAPLQERRIGGV---FQDLVVNTRQDMKHVKDS 116 R RG AGG A+SQG++ AG L ER GG F DL VNTRQ++ HVK+S Sbjct: 49 RGRQRGTAGGTAKSQGLQI---SAGFQELSLAER--GGRRRDFHDLGVNTRQNLDHVKES 103 Query: 117 KTGSEGTVVQLLANHFRVISRPQWVAYKYNVDYKPDIEDGNLRTILLDQHRRKFGERHIF 176 KTGS G +V+L NHFR+ SRPQW Y+Y++DY P +E LR+ LL QH G+ H F Sbjct: 104 KTGSSGIIVRLSTNHFRLTSRPQWALYQYHIDYNPLMEARRLRSALLFQHEDLIGKCHAF 163 Query: 177 DGNSLLLSRPLKERRVEWLSTTKDKNIVKITVEFSKELTPTSPDCLRYYNILFRRTFKLL 236 DG L L + L+++ E S T++ V+IT+ + EL PTSP CL++YNI+FRR K++ Sbjct: 164 DGTILFLPKRLQQKVTEVFSKTRNGEDVRITITLTNELPPTSPTCLQFYNIIFRRLLKIM 223 Query: 237 DFEQVGRNYYTKKKAIQLYRHGTSLEIWLGYVTSVLQYENSITLCADVSHKLLRIETAYD 296 + +Q+GRNYY I + H L IW G+ TS+LQYENSI LC DVSHK+LR ET D Sbjct: 224 NLQQIGRNYYNPNDPIDIPSH--RLVIWPGFTTSILQYENSIMLCTDVSHKVLRSETVLD 281 Query: 297 FIKRTSAQAQTGNIREEVTNKLIGSIVLTKYNNKTYRVDDIDWKQNPEDTFNKSDGSKIT 356 F+ Q + +E+V+ +LIG +VLTKYNNKTYRVDDIDW QNP+ TF K+DGS+++ Sbjct: 282 FMFNFYHQTEEHKFQEQVSKELIGLVVLTKYNNKTYRVDDIDWDQNPKSTFKKADGSEVS 341 Query: 357 YIDYYRQQHKEIVTVKKQPLLVSQGRWKKGLTGTQREPILLIPQLCHMTGLTDEICKDYS 416 +++YYR+Q+ + +T KQP+LVSQ + ++G GT P +LIP+LC++TGLTD++ D++ Sbjct: 342 FLEYYRKQYNQEITDLKQPVLVSQPKRRRGPGGTLPGPAMLIPELCYLTGLTDKMRNDFN 401 Query: 417 IVKELAKHTRLSPRRRHHTLKEFINTLQDNKKVRELLQLWDLKFDTNFLSVPGRVLKNAN 476 ++K+LA HTRL+P +R + I+ + N V+ L+ W L FD+N LS GR+L+ Sbjct: 402 VMKDLAVHTRLTPEQRQREVGRLIDYIHKNDNVQRELRDWGLSFDSNLLSFSGRILQTEK 461 Query: 477 IVQGRRMVKANSQ-GDWSREIRELPLLNAMPLHSWLILYSRSSHREAMSLKGHLQSVTAP 535 I QG + N Q DWS+E R PL++ PL +WL++Y+R ++ A SL +L VT Sbjct: 462 IHQGGKTFDYNPQFADWSKETRGAPLISVKPLDNWLLIYTRRNYEAANSLIQNLFKVTPA 521 Query: 536 MGITMKPAEMIEVDGDANSYIDTLRKYTRPTLQMGMSCLLVFKVICILPNDDKRRYDSIK 595 MG+ M+ A MIEVD +Y+ L++ Q+ V+C+L ++ K +YD+IK Sbjct: 522 MGMQMRKAIMIEVDDRTEAYLRVLQQKVTADTQI---------VVCLLSSNRKDKYDAIK 572 Query: 596 RYLCTKCPIPSQCVVKKTLEKVQ-ARTIVTKIAQQMNCKMGGALWKVETDVQRTMFVGID 654 +YLCT CP PSQCVV +TL K Q I TKIA QMNCKMGG LW+V+ ++ M VGID Sbjct: 573 KYLCTDCPTPSQCVVARTLGKQQTVMAIATKIALQMNCKMGGELWRVDIPLKLVMIVGID 632 Query: 655 CFHDIVNRQKSIAGFVASTNAELTKWYSQCVIQKTGEELVKELEICLKAALDVWCKNESS 714 C+HD+ ++SIAGFVAS N +T+W+S+C+ Q G+ELV L++CL+AAL W Sbjct: 633 CYHDMTAGRRSIAGFVASINEGMTRWFSRCIFQDRGQELVDGLKVCLQAALRAWNSCNEY 692 Query: 715 MPHSVIVYRDGVGDGQLQALLDHEAKKMSTYLKTISPN-NFTLAFIVVKKRINTRFFLKH 773 MP +IVYRDGVGDGQL+ L+++E + LK+I N L IVVKKR+NTRFF + Sbjct: 693 MPSRIIVYRDGVGDGQLKTLVNYEVPQFLDCLKSIGRGYNPRLTVIVVKKRVNTRFFAQS 752 Query: 774 GSNFQNPPPGTVIDVELTRNEWYDFFIVSQSVQDGTVTPTHYNVIYDTIGLSPDTVQRLT 833 G QNP PGTVIDVE+TR EWYDFFIVSQ+V+ G+V+PTHYNVIYD GL PD +QRLT Sbjct: 753 GGRLQNPLPGTVIDVEVTRPEWYDFFIVSQAVRSGSVSPTHYNVIYDNSGLKPDHIQRLT 812 Query: 834 YCLCHMYYNLPGIIRVPAPCHYAHKLAYLVGQSIHQEPNRSLSTRLFYL 882 Y LCH+YYN PG+IRVPAPC YAHKLA+LVGQSIH+EPN SLS RL+YL Sbjct: 813 YKLCHIYYNWPGVIRVPAPCQYAHKLAFLVGQSIHREPNLSLSNRLYYL 861 >gi|221316711 piwi-like 4 [Homo sapiens] Length = 852 Score = 637 bits (1643), Expect = 0.0 Identities = 345/886 (38%), Positives = 519/886 (58%), Gaps = 38/886 (4%) Query: 1 MPGRARTRARGRARRRESYQQEAPGGPRAPGSATTQEPPQLQSTPRPLQEEVPVVRPLQP 60 M GRAR +ARG AR S + E ++Q++P P ++ Sbjct: 1 MSGRARVKARGIAR-----------------SPSATEVGRIQASPLPRSVDLSN----NE 39 Query: 61 RAARGGAGGGAQSQGVKEPGPEAGLHTAPLQERRIGGV--FQDLVVNTRQDMKHVKDSKT 118 ++ G G ++ + G +G + ER + F DL + TR+ + HV++ KT Sbjct: 40 ASSSNGFLGTSRISTNDKYGISSGDAGSTFMERGVKNKQDFMDLSICTREKLAHVRNCKT 99 Query: 119 GSEGTVVQLLANHFRVISRPQWVAYKYNVDYKPDIEDGNLRTILLDQHRRKFGERHIFDG 178 GS G V+L+ N F + W Y+Y+V Y PD+ LR LL H + FDG Sbjct: 100 GSSGIPVKLVTNLFNLDFPQDWQLYQYHVTYIPDLASRRLRIALLYSHSELSNKAKAFDG 159 Query: 179 NSLLLSRPLKERRVEWLSTTKDKNIVKITVEFSKELTPTSPDCLRYYNILFRRTFKLLDF 238 L LS+ L+E+ E S T+ +K+T+ +EL +SP C++ +NI+FR+ K L Sbjct: 160 AILFLSQKLEEKVTELSSETQRGETIKMTITLKRELPSSSPVCIQVFNIIFRKILKKLSM 219 Query: 239 EQVGRNYYTKKKAIQLYRHGTSLEIWLGYVTSVLQYENSITLCADVSHKLLRIETAYDFI 298 Q+GRN+Y + +++ +H L +W G+ SV +E + ADVS+K+LR ET +F+ Sbjct: 220 YQIGRNFYNPSEPMEIPQH--KLSLWPGFAISVSYFERKLLFSADVSYKVLRNETVLEFM 277 Query: 299 KRTSAQAQTGNIREEVTNKLIGSIVLTKYNNKTYRVDDIDWKQNPEDTFNKSDGSKITYI 358 + + +LIG IVLT+YNN+TY +DDIDW P TF K DG++ITY+ Sbjct: 278 TALCQRTGLSCFTQTCEKQLIGLIVLTRYNNRTYSIDDIDWSVKPTHTFQKRDGTEITYV 337 Query: 359 DYYRQQHKEIVTVKKQPLLVSQGRWKKGLTGTQREPILLIPQLCHMTGLTDEICKDYSIV 418 DYY+QQ+ V+ QP+LVS + KK ++ + LIP+LC +TGLTD+ D+ ++ Sbjct: 338 DYYKQQYDITVSDLNQPMLVSLLK-KKRNDNSEAQLAHLIPELCFLTGLTDQATSDFQLM 396 Query: 419 KELAKHTRLSPRRRHHTLKEFINTLQDNKKVRELLQLWDLKFDTNFLSVPGRVLKNANIV 478 K +A+ TRLSP R L ++ +Q N R L+ W L F + +S+ GR++ + I+ Sbjct: 397 KAVAEKTRLSPSGRQQRLARLVDNIQRNTNARFELETWGLHFGSQ-ISLTGRIVPSEKIL 455 Query: 479 QGRRMVKANSQGDWSREIRELPLLNAMPLHSWLILYSRSSHREAMSLKGHLQSVTAPMGI 538 + + S DWS++IR +LNA L++WLIL S + A S L+ V MG Sbjct: 456 MQDHICQPVSAADWSKDIRTCKILNAQSLNTWLILCSDRTEYVAESFLNCLRRVAGSMGF 515 Query: 539 TMKPAEMIEVDGDANSYIDTLRKYTRPTLQMGMSCLLVFKVICILPNDDKRRYDSIKRYL 598 + ++I+V + +++ +++Y P +Q+ V+CILP++ K YDSIK+YL Sbjct: 516 NVDYPKIIKVQENPAAFVRAIQQYVDPDVQL---------VMCILPSNQKTYYDSIKKYL 566 Query: 599 CTKCPIPSQCVVKKTLEKV-QARTIVTKIAQQMNCKMGGALWKVETDVQRTMFVGIDCFH 657 + CP+PSQCV+ +TL K +I TKIA QM CK+GG LW VE ++ M VGID Sbjct: 567 SSDCPVPSQCVLARTLNKQGMMMSIATKIAMQMTCKLGGELWAVEIPLKSLMVVGIDVCK 626 Query: 658 DIVNRQKSIAGFVASTNAELTKWYSQCVIQKTGEELVKELEICLKAALDVWCKNESSMPH 717 D +++ + G VAS N +T+W+S+C++Q+T ++ L++ + AL+ W K +P Sbjct: 627 DALSKDVMVVGCVASVNPRITRWFSRCILQRTMTDVADCLKVFMTGALNKWYKYNHDLPA 686 Query: 718 SVIVYRDGVGDGQLQALLDHEAKKM-STYLKTISPNNFTLAFIVVKKRINTRFFLKHGSN 776 +IVYR GVGDGQL+ L+++E ++ S+ ++ S + L+ IVV+K+ RFF + Sbjct: 687 RIIVYRAGVGDGQLKTLIEYEVPQLLSSVAESSSNTSSRLSVIVVRKKCMPRFFTEMNRT 746 Query: 777 FQNPPPGTVIDVELTRNEWYDFFIVSQSVQDGTVTPTHYNVIYDTIGLSPDTVQRLTYCL 836 QNPP GTV+D E TRNEWYDF+++SQ GTV+PT+YNVIYD GL PD +QRLT+ L Sbjct: 747 VQNPPLGTVVDSEATRNEWYDFYLISQVACRGTVSPTYYNVIYDDNGLKPDHMQRLTFKL 806 Query: 837 CHMYYNLPGIIRVPAPCHYAHKLAYLVGQSIHQEPNRSLSTRLFYL 882 CH+YYN PGI+ VPAPC YAHKL +LV QSIH+EP+ L+ LFYL Sbjct: 807 CHLYYNWPGIVSVPAPCQYAHKLTFLVAQSIHKEPSLELANHLFYL 852 >gi|209180418 piwi-like 2 [Homo sapiens] Length = 973 Score = 514 bits (1323), Expect = e-145 Identities = 275/773 (35%), Positives = 444/773 (57%), Gaps = 22/773 (2%) Query: 117 KTGSEGTVVQLLANHFRVISRPQWVAYKYNVDYKPDIEDGNLRTILLDQHRRKFGERHIF 176 K GS+GT L N ++ + V Y+Y+V + P++E ++R +L H+ G F Sbjct: 216 KQGSKGTPQSLGLNLVKIQCHNEAV-YQYHVTFSPNVECKSMRFGMLKDHQAVTGNVTAF 274 Query: 177 DGNSLLLSRPLKERRVEWLSTTK--DKNIVKITVEFSKELTPTSPDCLRYYNILFRRTFK 234 DG+ L L P+K ++V L + + D + I ++ +K L P S C+ +YN++FRR K Sbjct: 275 DGSILYL--PVKLQQVLELKSQRKTDSAEISIKIQMTKILEPCSDLCIPFYNVVFRRVMK 332 Query: 235 LLDFEQVGRNYYTKKKAIQLYRHGTSLEIWLGYVTSVLQYENSITLCADVSHKLLRIETA 294 LLD + VGRN+Y A+ L +H L+IW GY S+ + + + L ADVSHK++R + Sbjct: 333 LLDMKLVGRNFYDPTSAMVLQQH--RLQIWPGYAASIRRTDGGLFLLADVSHKVIRNDCV 390 Query: 295 YDFIKRTSAQAQTGNIREEVTNKLIGSIVLTKYNNKTYRVDDIDWKQNPEDTFNKSDGSK 354 D + Q + ++E T L+G+IV+T+YNN+TYR+DD+DW + P+D+F SDG + Sbjct: 391 LD-VMHAIYQQNKEHFQDECTKLLVGNIVITRYNNRTYRIDDVDWNKTPKDSFTMSDGKE 449 Query: 355 ITYIDYYRQQHKEIVTVKKQPLLVSQGRWKKGLTGTQ-REPILLIPQLCHMTGLTDEICK 413 IT+++YY + + V + QPLL+ + ++ G + ILL+P+L MTG+ +++ K Sbjct: 450 ITFLEYYSKNYGITVKEEDQPLLIHRPSERQDNHGMLLKGEILLLPELSFMTGIPEKMKK 509 Query: 414 DYSIVKELAKHTRLSPRRRHHTLKEFINTLQDNKKVRELLQLWDLKFDTNFLSVPGRVLK 473 D+ +K+LA+ LSP++ H L+ + + N+ L W L+ + + GRVL Sbjct: 510 DFRAMKDLAQQINLSPKQHHSALECLLQRIAKNEAATNELMRWGLRLQKDVHKIEGRVLP 569 Query: 474 NANIVQGRRMVKANSQGDWSREIRELPLLNAMPLHSWLILYSRSSHREAMSLKGHLQSVT 533 I + + +W +E+ P + +P+H W + Y + + +A L L+ + Sbjct: 570 MERINLKNTSFITSQELNWVKEVTRDPSILTIPMHFWALFYPKRAMDQARELVNMLEKIA 629 Query: 534 APMGITMKPAEMIEVDGDA-NSYIDTLRKYTRPTLQMGMSCLLVFKVICIL--PNDDKRR 590 P+G+ M P +E+ D +Y+ T++ ++ M V+CI+ P DD Sbjct: 630 GPIGMRMSPPAWVELKDDRIETYVRTIQSTLGAEGKIQM-------VVCIIMGPRDDL-- 680 Query: 591 YDSIKRYLCTKCPIPSQCVVKKTL-EKVQARTIVTKIAQQMNCKMGGALWKVETDVQRTM 649 Y +IK+ C + P+PSQ V +T+ + + R++ KI Q+NCK+GG LW V+ +++ M Sbjct: 681 YGAIKKLCCVQSPVPSQVVNVRTIGQPTRLRSVAQKILLQINCKLGGELWGVDIPLKQLM 740 Query: 650 FVGIDCFHDIVNRQKSIAGFVASTNAELTKWYSQCVIQKTGEELVKELEICLKAALDVWC 709 +G+D +HD +S+ GFVAS N LTKWYS+ V Q +E+V L++CL +L + Sbjct: 741 VIGMDVYHDPSRGMRSVVGFVASINLTLTKWYSRVVFQMPHQEIVDSLKLCLVGSLKKFY 800 Query: 710 KNESSMPHSVIVYRDGVGDGQLQALLDHEAKKMSTYLKTISPNNFTLAFIVVKKRINTRF 769 + +P ++VYRDGV DGQL+ + ++E ++ + + VV+K+I+T Sbjct: 801 EVNHCLPEKIVVYRDGVSDGQLKTVANYEIPQLQKCFEAFENYQPKMVVFVVQKKISTNL 860 Query: 770 FLKHGSNFQNPPPGTVIDVELTRNEWYDFFIVSQSVQDGTVTPTHYNVIYDTIGLSPDTV 829 +L NF P PGTV+D +T EW DF++++ V+ G PTHY + +T LSPD + Sbjct: 861 YLAAPQNFVTPTPGTVVDHTITSCEWVDFYLLAHHVRQGCGIPTHYVCVLNTANLSPDHM 920 Query: 830 QRLTYCLCHMYYNLPGIIRVPAPCHYAHKLAYLVGQSIHQEPNRSLSTRLFYL 882 QRLT+ LCHMY+N PG IRVPAPC YAHKLA+L G +H EP L LF+L Sbjct: 921 QRLTFKLCHMYWNWPGTIRVPAPCKYAHKLAFLSGHILHHEPAIQLCENLFFL 973 >gi|24431985 piwi-like 2 [Homo sapiens] Length = 973 Score = 514 bits (1323), Expect = e-145 Identities = 275/773 (35%), Positives = 444/773 (57%), Gaps = 22/773 (2%) Query: 117 KTGSEGTVVQLLANHFRVISRPQWVAYKYNVDYKPDIEDGNLRTILLDQHRRKFGERHIF 176 K GS+GT L N ++ + V Y+Y+V + P++E ++R +L H+ G F Sbjct: 216 KQGSKGTPQSLGLNLVKIQCHNEAV-YQYHVTFSPNVECKSMRFGMLKDHQAVTGNVTAF 274 Query: 177 DGNSLLLSRPLKERRVEWLSTTK--DKNIVKITVEFSKELTPTSPDCLRYYNILFRRTFK 234 DG+ L L P+K ++V L + + D + I ++ +K L P S C+ +YN++FRR K Sbjct: 275 DGSILYL--PVKLQQVLELKSQRKTDSAEISIKIQMTKILEPCSDLCIPFYNVVFRRVMK 332 Query: 235 LLDFEQVGRNYYTKKKAIQLYRHGTSLEIWLGYVTSVLQYENSITLCADVSHKLLRIETA 294 LLD + VGRN+Y A+ L +H L+IW GY S+ + + + L ADVSHK++R + Sbjct: 333 LLDMKLVGRNFYDPTSAMVLQQH--RLQIWPGYAASIRRTDGGLFLLADVSHKVIRNDCV 390 Query: 295 YDFIKRTSAQAQTGNIREEVTNKLIGSIVLTKYNNKTYRVDDIDWKQNPEDTFNKSDGSK 354 D + Q + ++E T L+G+IV+T+YNN+TYR+DD+DW + P+D+F SDG + Sbjct: 391 LD-VMHAIYQQNKEHFQDECTKLLVGNIVITRYNNRTYRIDDVDWNKTPKDSFTMSDGKE 449 Query: 355 ITYIDYYRQQHKEIVTVKKQPLLVSQGRWKKGLTGTQ-REPILLIPQLCHMTGLTDEICK 413 IT+++YY + + V + QPLL+ + ++ G + ILL+P+L MTG+ +++ K Sbjct: 450 ITFLEYYSKNYGITVKEEDQPLLIHRPSERQDNHGMLLKGEILLLPELSFMTGIPEKMKK 509 Query: 414 DYSIVKELAKHTRLSPRRRHHTLKEFINTLQDNKKVRELLQLWDLKFDTNFLSVPGRVLK 473 D+ +K+LA+ LSP++ H L+ + + N+ L W L+ + + GRVL Sbjct: 510 DFRAMKDLAQQINLSPKQHHSALECLLQRIAKNEAATNELMRWGLRLQKDVHKIEGRVLP 569 Query: 474 NANIVQGRRMVKANSQGDWSREIRELPLLNAMPLHSWLILYSRSSHREAMSLKGHLQSVT 533 I + + +W +E+ P + +P+H W + Y + + +A L L+ + Sbjct: 570 MERINLKNTSFITSQELNWVKEVTRDPSILTIPMHFWALFYPKRAMDQARELVNMLEKIA 629 Query: 534 APMGITMKPAEMIEVDGDA-NSYIDTLRKYTRPTLQMGMSCLLVFKVICIL--PNDDKRR 590 P+G+ M P +E+ D +Y+ T++ ++ M V+CI+ P DD Sbjct: 630 GPIGMRMSPPAWVELKDDRIETYVRTIQSTLGAEGKIQM-------VVCIIMGPRDDL-- 680 Query: 591 YDSIKRYLCTKCPIPSQCVVKKTL-EKVQARTIVTKIAQQMNCKMGGALWKVETDVQRTM 649 Y +IK+ C + P+PSQ V +T+ + + R++ KI Q+NCK+GG LW V+ +++ M Sbjct: 681 YGAIKKLCCVQSPVPSQVVNVRTIGQPTRLRSVAQKILLQINCKLGGELWGVDIPLKQLM 740 Query: 650 FVGIDCFHDIVNRQKSIAGFVASTNAELTKWYSQCVIQKTGEELVKELEICLKAALDVWC 709 +G+D +HD +S+ GFVAS N LTKWYS+ V Q +E+V L++CL +L + Sbjct: 741 VIGMDVYHDPSRGMRSVVGFVASINLTLTKWYSRVVFQMPHQEIVDSLKLCLVGSLKKFY 800 Query: 710 KNESSMPHSVIVYRDGVGDGQLQALLDHEAKKMSTYLKTISPNNFTLAFIVVKKRINTRF 769 + +P ++VYRDGV DGQL+ + ++E ++ + + VV+K+I+T Sbjct: 801 EVNHCLPEKIVVYRDGVSDGQLKTVANYEIPQLQKCFEAFENYQPKMVVFVVQKKISTNL 860 Query: 770 FLKHGSNFQNPPPGTVIDVELTRNEWYDFFIVSQSVQDGTVTPTHYNVIYDTIGLSPDTV 829 +L NF P PGTV+D +T EW DF++++ V+ G PTHY + +T LSPD + Sbjct: 861 YLAAPQNFVTPTPGTVVDHTITSCEWVDFYLLAHHVRQGCGIPTHYVCVLNTANLSPDHM 920 Query: 830 QRLTYCLCHMYYNLPGIIRVPAPCHYAHKLAYLVGQSIHQEPNRSLSTRLFYL 882 QRLT+ LCHMY+N PG IRVPAPC YAHKLA+L G +H EP L LF+L Sbjct: 921 QRLTFKLCHMYWNWPGTIRVPAPCKYAHKLAFLSGHILHHEPAIQLCENLFFL 973 >gi|169217928 PREDICTED: similar to piwi like homolog 2 [Homo sapiens] Length = 349 Score = 171 bits (432), Expect = 4e-42 Identities = 92/297 (30%), Positives = 158/297 (53%), Gaps = 13/297 (4%) Query: 413 KDYSIVKELAKHTRLSPRRRHHTLKEFINTLQDNKKVRELLQLWDLKFDTNFLSVPGRVL 472 KD+ +K+LA+ LSP++ H L+ + + N+ L W L+ + + GRVL Sbjct: 3 KDFRAMKDLAQQINLSPKQHHSALECLLQRIAKNEAATNELMRWGLRLQKDVHKIEGRVL 62 Query: 473 KNANIVQGRRMVKANSQGDWSREIRELPLLNAMPLHSWLILYSRSSHREAMSLKGHLQSV 532 I + + +W +E+ P + +P+H W + Y + + +A L L+ + Sbjct: 63 PMERINLKNTSFITSQELNWVKEVTRDPSILTIPMHFWALFYPKRAMDQARELVNMLEKI 122 Query: 533 TAPMGITMKPAEMIEVDGDA-NSYIDTLRKYTRPTLQMGMSCLLVFKVICIL--PNDDKR 589 P+G+ M P +E+ D +Y+ T++ ++ M V+CI+ P DD Sbjct: 123 AGPIGMRMSPPAWVELKDDRIETYVRTIQSTLGAEGKIQM-------VVCIIMGPRDDL- 174 Query: 590 RYDSIKRYLCTKCPIPSQCVVKKTL-EKVQARTIVTKIAQQMNCKMGGALWKVETDVQRT 648 Y +IK+ C + P+PSQ V +T+ + + R++ KI Q+NCK+GG LW V+ +++ Sbjct: 175 -YGAIKKLCCVQSPVPSQVVNVRTIGQPTRLRSVAQKILLQINCKLGGELWGVDIPLKQL 233 Query: 649 MFVGIDCFHDIVNRQKSIAGFVASTNAELTKWYSQCVIQKTGEELVKELEICLKAAL 705 M +G+D +HD +S+ GFVAS N LTKWYS+ V Q +E+V L++CL +L Sbjct: 234 MVIGMDVYHDPSRGMRSVVGFVASINLTLTKWYSRVVFQMPHQEIVDSLKLCLVGSL 290 >gi|29171734 eukaryotic translation initiation factor 2C, 2 [Homo sapiens] Length = 859 Score = 156 bits (395), Expect = 7e-38 Identities = 200/814 (24%), Positives = 345/814 (42%), Gaps = 105/814 (12%) Query: 119 GSEGTVVQLLANHFRVISRPQWVAYKYNVDYKPDIEDGNLRTILLD---QHRRK--FGER 173 G+ G ++L AN F + P+ Y Y +D KP+ + +++ QH + FG+R Sbjct: 32 GTSGRTIKLQANFFEM-DIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDR 90 Query: 174 H-IFDGNSLLLSR---PLKERRVEWLSTT----KDKNIVKITVEF-------------SK 212 +FDG L + P+ +VE T KD+ I K+++++ S Sbjct: 91 KPVFDGRKNLYTAMPLPIGRDKVELEVTLPGEGKDR-IFKVSIKWVSCVSLQALHDALSG 149 Query: 213 ELTPTSPDCLRYYNILFRRTFKLLDFEQVGRNYYTKKKAIQLYRHGTSLEIWLGYVTSVL 272 L + ++ +++ R + + VGR+++T + G E+W G+ SV Sbjct: 150 RLPSVPFETIQALDVVMRH-LPSMRYTPVGRSFFTASEGCS-NPLGGGREVWFGFHQSVR 207 Query: 273 QYENSITLCADVSHKLLR-----IETAYDFIKRTSAQAQ----TGNIREEVTNKLIG--- 320 + L DVS IE + + S + Q T + R + T ++ G Sbjct: 208 PSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKV 267 Query: 321 SIVLTKYNNKTYRVDDIDWKQNPEDTFNKSDGS----KITYIDYYRQQHKEIVTVKKQPL 376 I + YRV ++ + TF S + T Y++ +HK ++ P Sbjct: 268 EITHCGQMKRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPC 327 Query: 377 LVSQGRWKKGLTGTQREPILLIPQLCHMTGLTDEICK--DYSIVKELAKHTRLSPRRRHH 434 L G +++ L ++C++ I K D + R +P R+ Sbjct: 328 LQ---------VGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEE 378 Query: 435 TLKEFIN-TLQDNKKVRELLQLWDLKFDTNFLSVPGRVLKNANIVQGRR--MVKANSQGD 491 K + + + VRE + + V GRVL+ +I+ G R + QG Sbjct: 379 ISKLMRSASFNTDPYVRE----FGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGV 434 Query: 492 WSREIRELPLLNAMPLHSWLILYSRSSHREAMSLKGHLQSVT---------APMGITMKP 542 W ++R + + W I + R+ + HL+S T A M I +P Sbjct: 435 W--DMRNKQFHTGIEIKVWAIACF-APQRQCTEV--HLKSFTEQLRKISRDAGMPIQGQP 489 Query: 543 AEMIEVDGDANSYIDTLR--KYTRPTLQMGMSCLLVFKVICILPNDDKRRYDSIKRYLCT 600 G A+S R K T LQ+ V+ ILP Y +KR T Sbjct: 490 CFCKYAQG-ADSVEPMFRHLKNTYAGLQL---------VVVILPGKTPV-YAEVKRVGDT 538 Query: 601 KCPIPSQCVVKKTLEKVQARTIVTKIAQQMNCKMGGA------LWKVETDVQRTMFVGID 654 + +QCV K +++ +T+ + + ++N K+GG + Q +F+G D Sbjct: 539 VLGMATQCVQMKNVQRTTPQTL-SNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGAD 597 Query: 655 CFHDIVN--RQKSIAGFVASTNAELTKWYSQCVIQKTGEELVKELEICLKAALDVWCKNE 712 H ++ SIA V S +A ++ + +Q+ +E++++L ++ L + K+ Sbjct: 598 VTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKST 657 Query: 713 SSMPHSVIVYRDGVGDGQLQALLDHEAKKM-STYLKTISPNNFTLAFIVVKKRINTRFFL 771 P +I YRDGV +GQ Q +L HE + +K + FIVV+KR +TR F Sbjct: 658 RFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFC 717 Query: 772 ----KHGSNFQNPPPGTVIDVELTRNEWYDFFIVSQSVQDGTVTPTHYNVIYDTIGLSPD 827 + N P GT +D ++T +DF++ S + GT P+HY+V++D S D Sbjct: 718 TDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSD 777 Query: 828 TVQRLTYCLCHMYYNLPGIIRVPAPCHYAHKLAY 861 +Q LTY LCH Y + +PAP +YAH +A+ Sbjct: 778 ELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAF 811 >gi|6912352 eukaryotic translation initiation factor 2C, 1 [Homo sapiens] Length = 857 Score = 147 bits (372), Expect = 3e-35 Identities = 188/816 (23%), Positives = 352/816 (43%), Gaps = 109/816 (13%) Query: 119 GSEGTVVQLLANHFRVISRPQWVAYKYNVDYKPDIEDGNLRTILLD---QHRRK--FGER 173 G+ G ++LLAN+F V P+ Y Y VD KPD + +++ QH + FG+R Sbjct: 30 GTVGKPIKLLANYFEV-DIPKIDVYHYEVDIKPDKCPRRVNREVVEYMVQHFKPQIFGDR 88 Query: 174 H-IFDGNS---LLLSRPLKERRVEWLSTT----KDKNIVKITVEFSKELT---------- 215 ++DG + + P+ RV++ T KD+ I K+++++ ++ Sbjct: 89 KPVYDGKKNIYTVTALPIGNERVDFEVTIPGEGKDR-IFKVSIKWLAIVSWRMLHEALVS 147 Query: 216 ---PTSPDCLRYYNILFRRTFKLLDFEQVGRNYYTKKKAIQLYRH--GTSLEIWLGYVTS 270 P + ++ ++ R + + VGR++++ + Y H G E+W G+ S Sbjct: 148 GQIPVPLESVQALDVAMRHLASMR-YTPVGRSFFSPPEG---YYHPLGGGREVWFGFHQS 203 Query: 271 VLQYENSITLCADVSHKLL-RIETAYDF------IKRTSAQAQ--TGNIREEVTNKLIGS 321 V + L DVS + + +F I+ Q + T + R T ++ G Sbjct: 204 VRPAMWKMMLNIDVSATAFYKAQPVIEFMCEVLDIRNIDEQPKPLTDSQRVRFTKEIKGL 263 Query: 322 IVLTKY---NNKTYRVDDIDWKQNPEDTF----NKSDGSKITYIDYYRQQHKEIVTVKKQ 374 V + + YRV ++ + TF + T Y++Q++ + Sbjct: 264 KVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLESGQTVECTVAQYFKQKYNLQLKYPHL 323 Query: 375 PLLVSQGRWKKGLTGTQREPILLIPQLCHMTG-------LTDEICKDYSIVKELAKHTRL 427 P L G +++ L ++C++ LTD + +++K A R Sbjct: 324 PCLQ---------VGQEQKHTYLPLEVCNIVAGQRCIKKLTDN--QTSTMIKATA---RS 369 Query: 428 SPRRRHHTLKEFINTLQDNKKVR--ELLQLWDLKFDTNFLSVPGRVLKNANIVQG--RRM 483 +P R+ E I+ L N +Q + +K + V GRVL + G R Sbjct: 370 APDRQ-----EEISRLMKNASYNLDPYIQEFGIKVKDDMTEVTGRVLPAPILQYGGRNRA 424 Query: 484 VKANSQGDWSREIRELPLLNAMPLHSWLILY---SRSSHREAM-SLKGHLQSVTAPMGIT 539 + +QG W ++R N + + W I + E + + L+ ++ G+ Sbjct: 425 IATPNQGVW--DMRGKQFYNGIEIKVWAIACFAPQKQCREEVLKNFTDQLRKISKDAGMP 482 Query: 540 MKPAEMIEVDGDANSYIDTLRKYTRPTLQMGMSCLLVFKVICILPNDDKRRYDSIKRYLC 599 ++ ++ + ++ + T G+ ++V ILP Y +KR Sbjct: 483 IQGQPCFCKYAQGADSVEPMFRHLKNTYS-GLQLIIV-----ILPGKTPV-YAEVKRVGD 535 Query: 600 TKCPIPSQCVVKKTLEKVQARTIVTKIAQQMNCKMGGALWKVETDVQRT-------MFVG 652 T + +QCV K + K +T+ + + ++N K+GG + + QR+ +F+G Sbjct: 536 TLLGMATQCVQVKNVVKTSPQTL-SNLCLKINVKLGG-INNILVPHQRSAVFQQPVIFLG 593 Query: 653 IDCFHDIVN--RQKSIAGFVASTNAELTKWYSQCVIQKTGEELVKELEICLKAALDVWCK 710 D H ++ SI V S +A +++ + +Q+ +E++++L ++ L + K Sbjct: 594 ADVTHPPAGDGKKPSITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSYMVRELLIQFYK 653 Query: 711 NESSMPHSVIVYRDGVGDGQLQALLDHEAKKM-STYLKTISPNNFTLAFIVVKKRINTRF 769 + P +I YRDGV +GQL +L +E + +K + +IVV+KR +TR Sbjct: 654 STRFKPTRIIFYRDGVPEGQLPQILHYELLAIRDACIKLEKDYQPGITYIVVQKRHHTRL 713 Query: 770 FLKHGSN----FQNPPPGTVIDVELTRNEWYDFFIVSQSVQDGTVTPTHYNVIYDTIGLS 825 F + N P GT +D +T +DF++ S + GT P+HY V++D + Sbjct: 714 FCADKNERIGKSGNIPAGTTVDTNITHPFEFDFYLCSHAGIQGTSRPSHYYVLWDDNRFT 773 Query: 826 PDTVQRLTYCLCHMYYNLPGIIRVPAPCHYAHKLAY 861 D +Q LTY LCH Y + +PAP +YA +A+ Sbjct: 774 ADELQILTYQLCHTYVRCTRSVSIPAPAYYARLVAF 809 >gi|29294647 eukaryotic translation initiation factor 2C, 3 isoform a [Homo sapiens] Length = 860 Score = 144 bits (363), Expect = 4e-34 Identities = 190/824 (23%), Positives = 342/824 (41%), Gaps = 116/824 (14%) Query: 119 GSEGTVVQLLANHFRVISRPQWVAYKYNVDYKPDIEDGNLRTILLD---QHRRK--FGER 173 G+ G ++LLAN F+V P+ Y Y VD KPD + ++D QH + FG+R Sbjct: 24 GTMGKPIKLLANCFQV-EIPKIDVYLYEVDIKPDKCPRRVNREVVDSMVQHFKVTIFGDR 82 Query: 174 H-IFDGN-SLLLSRPL------------------KER----------RVEW--LSTTKDK 201 ++DG SL + PL K+R RV W L Sbjct: 83 RPVYDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRPFKVSIKFVSRVSWHLLHEVLTG 142 Query: 202 NIVKITVEFSKELTPTSPDCLRYYNILFRRTFKLLDFEQVGRNYYTKKKAIQLYRH--GT 259 + +E K P S + + +++ R + + VGR++++ + Y H G Sbjct: 143 RTLPEPLELDK---PISTNPVHAVDVVLRH-LPSMKYTPVGRSFFSAPEG---YDHPLGG 195 Query: 260 SLEIWLGYVTSVLQYENSITLCADVSHKLL-RIETAYDFIKRT--------SAQAQTGNI 310 E+W G+ SV + L DVS + + F+ + T + Sbjct: 196 GREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQFMCEVLDIHNIDEQPRPLTDSH 255 Query: 311 REEVTNKLIGSIVLTKY---NNKTYRVDDIDWKQNPEDTF--NKSDGSKI--TYIDYYRQ 363 R + T ++ G V + + YRV ++ + TF +G + T Y+R+ Sbjct: 256 RVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLENGQTVERTVAQYFRE 315 Query: 364 QHKEIVTVKKQPLLVSQGRWKKGLTGTQREPILLIPQLCHMTG-------LTDEICKDYS 416 ++ + P L G +++ L ++C++ LTD + Sbjct: 316 KYTLQLKYPHLPCLQ---------VGQEQKHTYLPLEVCNIVAGQRCIKKLTD------N 360 Query: 417 IVKELAKHTRLSPRRRHHTLKEFINTLQDNKKVRELLQLWDLKFDTNFLSVPGRVLKNAN 476 + K T S R + + + N + +Q + K V GRVL Sbjct: 361 QTSTMIKATARSAPDRQEEISRLVRSA--NYETDPFVQEFQFKVRDEMAHVTGRVLPAPM 418 Query: 477 IVQG--RRMVKANSQGDWSREIRELPLLNAMPLHSWLIL-YSRSSHREAMSLKG---HLQ 530 + G R V S G W ++R + + W I ++ LKG L+ Sbjct: 419 LQYGGRNRTVATPSHGVW--DMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLR 476 Query: 531 SVTAPMGITMKPAEMIEVDGDANSYIDTLRKYTRPTLQMGMSCLLVFKVICILPNDDKRR 590 ++ G+ ++ ++ + ++ + T G+ ++V ILP Sbjct: 477 KISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYS-GLQLIIV-----ILPGKTPV- 529 Query: 591 YDSIKRYLCTKCPIPSQCVVKKTLEKVQARTIVTKIAQQMNCKMGGAL------WKVETD 644 Y +KR T + +QCV K + K +T+ + + ++N K+GG + Sbjct: 530 YAEVKRVGDTLLGMATQCVQVKNVIKTSPQTL-SNLCLKINVKLGGINNILVPHQRPSVF 588 Query: 645 VQRTMFVGIDCFHDIVN--RQKSIAGFVASTNAELTKWYSQCVIQKTGEELVKELEICLK 702 Q +F+G D H ++ SIA V S +A +++ + +Q+ +E++++L ++ Sbjct: 589 QQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVR 648 Query: 703 AALDVWCKNESSMPHSVIVYRDGVGDGQLQALLDHEAKKMSTYLKTISPNNFT-LAFIVV 761 L + K+ P +I YRDGV +GQ + +L +E + ++ + + +IVV Sbjct: 649 ELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVV 708 Query: 762 KKRINTRFFL----KHGSNFQNPPPGTVIDVELTRNEWYDFFIVSQSVQDGTVTPTHYNV 817 +KR +TR F + N P GT +D ++T +DF++ S + GT P+HY+V Sbjct: 709 QKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHV 768 Query: 818 IYDTIGLSPDTVQRLTYCLCHMYYNLPGIIRVPAPCHYAHKLAY 861 ++D + D +Q LTY LCH Y + +PAP +YAH +A+ Sbjct: 769 LWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAF 812 >gi|29029593 eukaryotic translation initiation factor 2C, 4 [Homo sapiens] Length = 861 Score = 135 bits (339), Expect = 2e-31 Identities = 182/826 (22%), Positives = 345/826 (41%), Gaps = 117/826 (14%) Query: 119 GSEGTVVQLLANHFRVISRPQWVAYKYNVDYKPDIEDGNLRTILLDQHRRKF-------- 170 G+ G ++LLANHF+V P+ Y Y+VD KP+ + ++D R F Sbjct: 22 GTVGKPIRLLANHFQV-QIPKIDVYHYDVDIKPEKRPRRVNREVVDTMVRHFKMQIFGDR 80 Query: 171 -----GERHIFDGNSLLLSRPLKERRVEWLSTTKDKNIVKITVEF-------------SK 212 G+R+++ + L + R + V KD+ K++V++ + Sbjct: 81 QPGYDGKRNMYTAHPLPIGRDRVDMEVTLPGEGKDQTF-KVSVQWVSVVSLQLLLEALAG 139 Query: 213 ELTPTSPDCLRYYNILFRRTFKLLDFEQVGRNYYTKKKAIQLYRH--GTSLEIWLGYVTS 270 L D ++ +++ R + + VGR++++ + Y H G E+W G+ S Sbjct: 140 HLNEVPDDSVQALDVITRH-LPSMRYTPVGRSFFSPPEG---YYHPLGGGREVWFGFHQS 195 Query: 271 VLQYENSITLCADVSHKLL-RIETAYDF------IKRTSAQAQ--TGNIREEVTNKLIGS 321 V ++ L DVS R + +F I+ + Q + T + R + T ++ G Sbjct: 196 VRPAMWNMMLNIDVSATAFYRAQPIIEFMCEVLDIQNINEQTKPLTDSQRVKFTKEIRGL 255 Query: 322 IVLTKY---NNKTYRVDDIDWKQNPEDTF----NKSDGSKITYIDYYRQQHKEIVTVKKQ 374 V + + YRV ++ + TF + T Y++Q++ + Sbjct: 256 KVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLENGQAMECTVAQYFKQKYSLQLKYPHL 315 Query: 375 PLLVSQGRWKKGLTGTQREPILLIPQLCHMTG-------LTDEICKDYSIVKELAKHTRL 427 P L G +++ L ++C++ LTD + +++K A R Sbjct: 316 PCLQ---------VGQEQKHTYLPLEVCNIVAGQRCIKKLTDN--QTSTMIKATA---RS 361 Query: 428 SPRRRHHTLKEFINTLQDNKKVR---ELLQLWDLKFDTNFLSVPGRVLKNANIVQGRR-- 482 +P R+ +E ++ N V L+ + + + GRVL + G R Sbjct: 362 APDRQ----EEISRLVKSNSMVGGPDPYLKEFGIVVHNEMTELTGRVLPAPMLQYGGRNK 417 Query: 483 MVKANSQGDWSREIRELPLLNAMPLHSWLI--LYSRSSHREAM--SLKGHLQSVTAPMGI 538 V +QG W ++R + + W + + RE + S L+ ++ G+ Sbjct: 418 TVATPNQGVW--DMRGKQFYAGIEIKVWAVACFAPQKQCREDLLKSFTDQLRKISKDAGM 475 Query: 539 TMKPAEMIEVDGDANSYIDTLRKYTRPTLQMGMSCLLVFKVICILPNDDKRRYDSIKRYL 598 ++ ++ + K+ + T +G+ ++V ILP Y +KR Sbjct: 476 PIQGQPCFCKYAQGADSVEPMFKHLKMTY-VGLQLIVV-----ILPGKTPV-YAEVKRVG 528 Query: 599 CTKCPIPSQCVVKKTLEKVQARTIVTKIAQQMNCKMGGAL------WKVETDVQRTMFVG 652 T + +QCV K + K +T+ + + ++N K+GG + Q +F+G Sbjct: 529 DTLLGMATQCVQVKNVVKTSPQTL-SNLCLKINAKLGGINNVLVPHQRPSVFQQPVIFLG 587 Query: 653 IDCFHDIVN--RQKSIAGFVASTNAELTKWYSQCVIQKTGEELVKELEICLKAALDV--- 707 D H ++ SIA V S + +++ + +Q + +E+ +EL + D+ Sbjct: 588 ADVTHPPAGDGKKPSIAAVVGSMDGHPSRYCATVRVQTSRQEISQELLYSQEVIQDLTNM 647 Query: 708 -------WCKNESSMPHSVIVYRDGVGDGQLQALLDHEAKKMSTYLKTISPNNFT-LAFI 759 + K+ P +I YR GV +GQ++ + E + ++ + + +I Sbjct: 648 VRELLIQFYKSTRFKPTRIIYYRGGVSEGQMKQVAWPELIAIRKACISLEEDYRPGITYI 707 Query: 760 VVKKRINTRFFL----KHGSNFQNPPPGTVIDVELTRNEWYDFFIVSQSVQDGTVTPTHY 815 VV+KR +TR F + N P GT +D +T +DF++ S + GT P+HY Sbjct: 708 VVQKRHHTRLFCADKTERVGKSGNVPAGTTVDSTITHPSEFDFYLCSHAGIQGTSRPSHY 767 Query: 816 NVIYDTIGLSPDTVQRLTYCLCHMYYNLPGIIRVPAPCHYAHKLAY 861 V++D + D +Q LTY LCH Y + +PAP +YA +A+ Sbjct: 768 QVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYARLVAF 813 >gi|29337286 eukaryotic translation initiation factor 2C, 3 isoform b [Homo sapiens] Length = 626 Score = 129 bits (324), Expect = 1e-29 Identities = 113/460 (24%), Positives = 206/460 (44%), Gaps = 31/460 (6%) Query: 421 LAKHTRLSPRRRHHTLKEFINTLQDNKKVRELLQLWDLKFDTNFLSVPGRVLKNANIVQG 480 + K T S R + + + N + +Q + K V GRVL + G Sbjct: 131 MIKATARSAPDRQEEISRLVRSA--NYETDPFVQEFQFKVRDEMAHVTGRVLPAPMLQYG 188 Query: 481 --RRMVKANSQGDWSREIRELPLLNAMPLHSWLIL-YSRSSHREAMSLKG---HLQSVTA 534 R V S G W ++R + + W I ++ LKG L+ ++ Sbjct: 189 GRNRTVATPSHGVW--DMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISK 246 Query: 535 PMGITMKPAEMIEVDGDANSYIDTLRKYTRPTLQMGMSCLLVFKVICILPNDDKRRYDSI 594 G+ ++ ++ + ++ + T G+ ++V ILP Y + Sbjct: 247 DAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYS-GLQLIIV-----ILPGKTPV-YAEV 299 Query: 595 KRYLCTKCPIPSQCVVKKTLEKVQARTIVTKIAQQMNCKMGGAL------WKVETDVQRT 648 KR T + +QCV K + K +T+ + + ++N K+GG + Q Sbjct: 300 KRVGDTLLGMATQCVQVKNVIKTSPQTL-SNLCLKINVKLGGINNILVPHQRPSVFQQPV 358 Query: 649 MFVGIDCFHDIVN--RQKSIAGFVASTNAELTKWYSQCVIQKTGEELVKELEICLKAALD 706 +F+G D H ++ SIA V S +A +++ + +Q+ +E++++L ++ L Sbjct: 359 IFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLI 418 Query: 707 VWCKNESSMPHSVIVYRDGVGDGQLQALLDHEAKKMSTYLKTISPNNFT-LAFIVVKKRI 765 + K+ P +I YRDGV +GQ + +L +E + ++ + + +IVV+KR Sbjct: 419 QFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRH 478 Query: 766 NTRFFL----KHGSNFQNPPPGTVIDVELTRNEWYDFFIVSQSVQDGTVTPTHYNVIYDT 821 +TR F + N P GT +D ++T +DF++ S + GT P+HY+V++D Sbjct: 479 HTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDD 538 Query: 822 IGLSPDTVQRLTYCLCHMYYNLPGIIRVPAPCHYAHKLAY 861 + D +Q LTY LCH Y + +PAP +YAH +A+ Sbjct: 539 NCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAF 578 >gi|239750966 PREDICTED: hypothetical protein XP_002347633 [Homo sapiens] Length = 261 Score = 37.7 bits (86), Expect = 0.047 Identities = 25/75 (33%), Positives = 32/75 (42%), Gaps = 6/75 (8%) Query: 2 PGRARTRARGRARRRESYQQEAPG------GPRAPGSATTQEPPQLQSTPRPLQEEVPVV 55 PG AR RGRA R + G GP +P +A T PP + P P E + Sbjct: 183 PGSARRPRRGRAGRGGAAPAPPTGSMRAGPGPSSPSAAPTSHPPPSPACPGPEMETILRN 242 Query: 56 RPLQPRAARGGAGGG 70 P + A G+G G Sbjct: 243 PPARSPGAGWGSGAG 257 >gi|239745372 PREDICTED: hypothetical protein XP_002343483 [Homo sapiens] Length = 261 Score = 37.7 bits (86), Expect = 0.047 Identities = 25/75 (33%), Positives = 32/75 (42%), Gaps = 6/75 (8%) Query: 2 PGRARTRARGRARRRESYQQEAPG------GPRAPGSATTQEPPQLQSTPRPLQEEVPVV 55 PG AR RGRA R + G GP +P +A T PP + P P E + Sbjct: 183 PGSARRPRRGRAGRGGAAPAPPTGSMRAGPGPSSPSAAPTSHPPPSPACPGPEMETILRN 242 Query: 56 RPLQPRAARGGAGGG 70 P + A G+G G Sbjct: 243 PPARSPGAGWGSGAG 257 >gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] Length = 538 Score = 36.6 bits (83), Expect = 0.11 Identities = 31/88 (35%), Positives = 35/88 (39%), Gaps = 7/88 (7%) Query: 6 RTRARGRARRRESYQQEAPGGPR-APGSATTQEPPQLQSTPRPLQEEVPVVRPLQPRAAR 64 R AR + RR + P PR AP +A PP TP P PV RA R Sbjct: 94 RNAARVQPPRRGATPPAPPRAPRGAPAAAAAAAPPP---TPAPPPPPAPVAAAAPARAPR 150 Query: 65 GGAGGGAQ--SQGVKEPGPEAGLHTAPL 90 A S G +PGP A APL Sbjct: 151 AAAAAATAPPSPGPAQPGPRA-QRAAPL 177 >gi|112734870 hypothetical protein LOC57648 [Homo sapiens] Length = 1094 Score = 35.4 bits (80), Expect = 0.23 Identities = 26/83 (31%), Positives = 36/83 (43%), Gaps = 19/83 (22%) Query: 20 QQEAPGGPRAPGSATTQEPPQLQSTPRPLQEEVPVVRPLQPRAARGGAGGGAQ-SQGVKE 78 ++EAPG PRAPG+ P + P RG +G GA+ S E Sbjct: 238 EREAPGTPRAPGARDAVRIPTVDGRP------------------RGTSGMGARVSLQALE 279 Query: 79 PGPEAGLHTAPLQERRIGGVFQD 101 EAG T + +R I V++D Sbjct: 280 AEAEAGAETEAMLQRHIDRVYRD 302 >gi|50843837 hypothetical protein LOC55701 [Homo sapiens] Length = 1519 Score = 35.4 bits (80), Expect = 0.23 Identities = 28/97 (28%), Positives = 40/97 (41%), Gaps = 22/97 (22%) Query: 1 MPGRARTRARGRARRRESYQQEAPGGPRA------PGS-----ATTQEPPQLQSTPRPLQ 49 +P R +GR RR ++ + GPR PG A+ + PP ++ P Sbjct: 271 VPTRKGAGGKGRHRRHRAWMHQKGLGPRGQDGARPPGEGSSTGASPESPPGAEAVPEAAV 330 Query: 50 EEV--PVVR---------PLQPRAARGGAGGGAQSQG 75 EV P PL+P RGG GGG ++G Sbjct: 331 LEVSEPPAEAVGEASGSCPLRPGELRGGGGGGQGAEG 367 >gi|223633935 hypothetical protein LOC254427 [Homo sapiens] Length = 435 Score = 35.0 bits (79), Expect = 0.31 Identities = 31/97 (31%), Positives = 42/97 (43%), Gaps = 7/97 (7%) Query: 7 TRARGRARRRESYQQ---EAPGGPRAPGSATTQEPPQLQSTPRPLQEEVPVVRP--LQPR 61 T+A G A + +++ E P P P T PP L STP P + E+ P PR Sbjct: 127 TQAAGPAPAGKEHRKQDAETPPPPDPPAPETLLAPPPLPSTPDPPRRELRAPSPPVEHPR 186 Query: 62 AARGGAGGGAQSQGVKE--PGPEAGLHTAPLQERRIG 96 R +Q + E G EA T+P +E R G Sbjct: 187 LLRSVPTPLVMAQKISERMAGNEALSPTSPFREGRPG 223 >gi|51173735 ras responsive element binding protein 1 isoform 2 [Homo sapiens] Length = 1687 Score = 35.0 bits (79), Expect = 0.31 Identities = 22/73 (30%), Positives = 36/73 (49%), Gaps = 5/73 (6%) Query: 13 ARRRESYQQEAPGGPRAPGSATTQEPPQLQSTPRPLQEEVPVVRPLQPRAARGGAG-GGA 71 +R R+++ ++ P + G++T +E PQ P P QEE P P + + GAG A Sbjct: 1409 SRHRKAHGRQEPKDEKGDGASTAEEGPQ----PAPEQEEKPPETPAEVVESAPGAGEAPA 1464 Query: 72 QSQGVKEPGPEAG 84 + + GP G Sbjct: 1465 EKLAEETEGPSDG 1477 >gi|51173737 ras responsive element binding protein 1 isoform 1 [Homo sapiens] Length = 1742 Score = 35.0 bits (79), Expect = 0.31 Identities = 22/73 (30%), Positives = 36/73 (49%), Gaps = 5/73 (6%) Query: 13 ARRRESYQQEAPGGPRAPGSATTQEPPQLQSTPRPLQEEVPVVRPLQPRAARGGAG-GGA 71 +R R+++ ++ P + G++T +E PQ P P QEE P P + + GAG A Sbjct: 1464 SRHRKAHGRQEPKDEKGDGASTAEEGPQ----PAPEQEEKPPETPAEVVESAPGAGEAPA 1519 Query: 72 QSQGVKEPGPEAG 84 + + GP G Sbjct: 1520 EKLAEETEGPSDG 1532 >gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] Length = 904 Score = 35.0 bits (79), Expect = 0.31 Identities = 24/96 (25%), Positives = 37/96 (38%), Gaps = 2/96 (2%) Query: 2 PGRARTRARGRARRRESYQQEAPGGPRAPGSATTQEPPQLQSTPRPLQEEVPVVRPLQPR 61 P R R R R+R R + P R P P ++ PR + PV R + Sbjct: 293 PSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSS 352 Query: 62 AARGGAGGGAQSQGVKEP--GPEAGLHTAPLQERRI 95 A+ G+ + S + P P + P + RR+ Sbjct: 353 ASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRL 388 >gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] Length = 2217 Score = 34.7 bits (78), Expect = 0.40 Identities = 35/122 (28%), Positives = 50/122 (40%), Gaps = 28/122 (22%) Query: 17 ESYQQEAPG--GPRAPGSATTQEPPQ--------LQSTPRPLQEEV--------PVVRPL 58 ES Q+E PG APG +PPQ L T R + E P Sbjct: 48 ESDQEEPPGLEAAEAPGP----QPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVA 103 Query: 59 QPRAARGGAGGGAQSQGVKEPGPE---AGLHTAPLQERRIGGVFQDLVVNTRQDMKHVKD 115 QP A A G + G +EPGP+ A + TAP + GG ++ R++ + + Sbjct: 104 QPGAPGAPADAGPEPVGTQEPGPDPIAAAVETAPAPD---GGPREEAAATVRKEDEGAAE 160 Query: 116 SK 117 +K Sbjct: 161 AK 162 >gi|18079216 CASK interacting protein 1 [Homo sapiens] Length = 1431 Score = 34.3 bits (77), Expect = 0.52 Identities = 23/72 (31%), Positives = 32/72 (44%), Gaps = 6/72 (8%) Query: 27 PRAPGSATTQEPPQLQSTPRPLQEEVPVVRPLQPRAARGGAGGGAQSQGVKEPGPEAGLH 86 P +P TQ P+LQ +P P ++VP+ P P R A G K P P Sbjct: 1225 PVSPKPVLTQPVPKLQGSPTPTSKKVPLPGPGSPEVKR--AHGTPPPVSPKPPPPP---- 1278 Query: 87 TAPLQERRIGGV 98 TAP + + G+ Sbjct: 1279 TAPKPVKAVAGL 1290 >gi|239746530 PREDICTED: hypothetical protein XP_002343754 [Homo sapiens] Length = 536 Score = 34.3 bits (77), Expect = 0.52 Identities = 28/80 (35%), Positives = 32/80 (40%), Gaps = 6/80 (7%) Query: 2 PGRARTRARGRARRRESYQQEAPGGPRAPGSATTQEPPQLQSTPRPLQEEVPVVRPLQPR 61 P R R R R Q PGG RAPG P P P ++ VRPL Sbjct: 171 PSRCLGRLEPRRWRGHGLQ---PGGARAPGLQVPAPPGPASPAPLPARQPHKGVRPL--G 225 Query: 62 AARGG-AGGGAQSQGVKEPG 80 RGG A Q +G+ PG Sbjct: 226 CCRGGRAQAAGQPRGLCLPG 245 >gi|239751186 PREDICTED: WD repeat domain 81 [Homo sapiens] Length = 2240 Score = 33.9 bits (76), Expect = 0.68 Identities = 30/112 (26%), Positives = 42/112 (37%), Gaps = 7/112 (6%) Query: 2 PGRARTRARGRARRRESYQQEAPGGPRAPGSATTQEPPQLQSTPRPLQEEVPVVRPLQPR 61 PG R RA R ++ P AP P+ TP + V L P Sbjct: 234 PGAQDPRRGKRAPRPPLRRRRLPAAASAPAPVPRPSQPRRPGTPEAVASR--AVAGLSPA 291 Query: 62 AARGGAGGGAQSQGVKEPG---PEAGLHTAPLQERR--IGGVFQDLVVNTRQ 108 GG AQ G +E P G H+ P + + + V +DL ++ RQ Sbjct: 292 LPPGGLEEMAQGSGGREGALRTPAGGWHSPPSPDMQELLRSVERDLSIDPRQ 343 >gi|239749150 PREDICTED: hypothetical protein XP_002346928 [Homo sapiens] Length = 229 Score = 33.9 bits (76), Expect = 0.68 Identities = 22/60 (36%), Positives = 28/60 (46%), Gaps = 1/60 (1%) Query: 28 RAPGSATTQEPPQLQSTPRPLQEEVPVVRPLQPRAARGGAGGGAQSQGVKEPGPEAGLHT 87 R G +T+E + +P EV R RA GGAGG Q+ GV E G + G T Sbjct: 16 RQSGDRSTREAGMKEPPLQPKAPEVTFARRAL-RACAGGAGGAGQAGGVCEAGADWGAQT 74 >gi|19924103 synapsin II isoform IIa [Homo sapiens] Length = 582 Score = 33.9 bits (76), Expect = 0.68 Identities = 26/78 (33%), Positives = 34/78 (43%), Gaps = 4/78 (5%) Query: 15 RRESYQQEAPGGPRAPGSATTQE-PPQLQSTP--RPLQEEVPVVRPLQPRAARGGAGGGA 71 +R QQ P P PG+A+ PP P RP P +P P + G + + Sbjct: 27 QRPEPQQPPPPPPPGPGAASASAAPPTASPGPERRPPPASAPAPQPA-PTPSVGSSFFSS 85 Query: 72 QSQGVKEPGPEAGLHTAP 89 SQ VK+ AGL AP Sbjct: 86 LSQAVKQTAASAGLVDAP 103 >gi|193082982 zinc finger protein 837 isoform 1 [Homo sapiens] Length = 531 Score = 33.9 bits (76), Expect = 0.68 Identities = 22/71 (30%), Positives = 29/71 (40%), Gaps = 1/71 (1%) Query: 20 QQEAPGG-PRAPGSATTQEPPQLQSTPRPLQEEVPVVRPLQPRAARGGAGGGAQSQGVKE 78 Q+ GG P+A + + PRPL+E+ RP Q RG AGG G Sbjct: 6 QKAGQGGLPKADAQGASGAREKRPEEPRPLEEDRAGSRPTQKGDLRGAAGGRTTPPGGGS 65 Query: 79 PGPEAGLHTAP 89 G G+ P Sbjct: 66 RGCSLGVSPGP 76 >gi|193082980 zinc finger protein 837 isoform 2 [Homo sapiens] Length = 531 Score = 33.9 bits (76), Expect = 0.68 Identities = 22/71 (30%), Positives = 29/71 (40%), Gaps = 1/71 (1%) Query: 20 QQEAPGG-PRAPGSATTQEPPQLQSTPRPLQEEVPVVRPLQPRAARGGAGGGAQSQGVKE 78 Q+ GG P+A + + PRPL+E+ RP Q RG AGG G Sbjct: 6 QKAGQGGLPKADAQGASGAREKRPEEPRPLEEDRAGSRPTQKGDLRGAAGGRTTPPGGGS 65 Query: 79 PGPEAGLHTAP 89 G G+ P Sbjct: 66 RGCSLGVSPGP 76 >gi|19924101 synapsin II isoform IIb [Homo sapiens] Length = 478 Score = 33.9 bits (76), Expect = 0.68 Identities = 26/78 (33%), Positives = 34/78 (43%), Gaps = 4/78 (5%) Query: 15 RRESYQQEAPGGPRAPGSATTQE-PPQLQSTP--RPLQEEVPVVRPLQPRAARGGAGGGA 71 +R QQ P P PG+A+ PP P RP P +P P + G + + Sbjct: 27 QRPEPQQPPPPPPPGPGAASASAAPPTASPGPERRPPPASAPAPQPA-PTPSVGSSFFSS 85 Query: 72 QSQGVKEPGPEAGLHTAP 89 SQ VK+ AGL AP Sbjct: 86 LSQAVKQTAASAGLVDAP 103 >gi|238908524 hypothetical protein LOC389333 [Homo sapiens] Length = 1015 Score = 33.5 bits (75), Expect = 0.89 Identities = 29/91 (31%), Positives = 36/91 (39%), Gaps = 10/91 (10%) Query: 3 GRARTRARGRARRRESYQQEAPGGPRAPGSATTQEPPQLQSTPRPLQEEVPVVRPLQPRA 62 G RT G AR P G R+P + PQ+Q++P P P P P Sbjct: 772 GDGRTSPLGGARSSSQRSPVGPAGVRSPRPGS----PQMQASPSPGIAPKPKTPPTAPEP 827 Query: 63 ARGGAGGGAQSQGVKEPGPEAGLHTAPLQER 93 A Q+ +EP AG TAP Q R Sbjct: 828 A-----AAVQAPLPREPLALAG-RTAPAQPR 852 Score = 31.6 bits (70), Expect = 3.4 Identities = 26/81 (32%), Positives = 34/81 (41%), Gaps = 6/81 (7%) Query: 2 PGR-ARTRARGRARRRESYQQEAPGG--PRAPGSATTQEPPQLQSTPRPLQEEVPVVRPL 58 PGR A + R + S Q+ PG PR PGS PQL++ P E+ V+ + Sbjct: 61 PGRGAGAQPRLSVSAQNSRQRHGPGSGFPRGPGSGPRPPQPQLRTLP---SGEMEVIFGV 117 Query: 59 QPRAARGGAGGGAQSQGVKEP 79 P GA Q EP Sbjct: 118 GPLFGCSGADDREAQQQFTEP 138 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.135 0.408 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 35,044,892 Number of Sequences: 37866 Number of extensions: 1662376 Number of successful extensions: 7205 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 34 Number of HSP's successfully gapped in prelim test: 126 Number of HSP's that attempted gapping in prelim test: 6938 Number of HSP's gapped (non-prelim): 328 length of query: 882 length of database: 18,247,518 effective HSP length: 111 effective length of query: 771 effective length of database: 14,044,392 effective search space: 10828226232 effective search space used: 10828226232 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.