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Search of human proteins with 153791514
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|153791514 tripartite motif-containing 32 [Homo sapiens]
(653 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|153791514 tripartite motif-containing 32 [Homo sapiens] 1315 0.0
gi|153792582 tripartite motif-containing 32 [Homo sapiens] 1315 0.0
gi|194248081 tripartite motif-containing 2 isoform 2 [Homo sapiens] 117 4e-26
gi|194248079 tripartite motif-containing 2 isoform 1 [Homo sapiens] 117 4e-26
gi|84993742 tripartite motif-containing 71 [Homo sapiens] 74 6e-13
gi|32454739 tripartite motif-containing 3 [Homo sapiens] 72 1e-12
gi|32454737 tripartite motif-containing 3 [Homo sapiens] 72 1e-12
gi|60593056 hypothetical protein LOC283948 [Homo sapiens] 72 1e-12
gi|15208660 tripartite motif protein 21 [Homo sapiens] 72 2e-12
gi|157743261 tripartite motif-containing 75 [Homo sapiens] 71 4e-12
gi|209862805 SPRY domain containing 5 [Homo sapiens] 70 8e-12
gi|27436877 tripartite motif-containing 59 [Homo sapiens] 69 2e-11
gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens] 67 4e-11
gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens] 67 4e-11
gi|51477690 tripartite motif-containing 6 and tripartite motif-c... 67 4e-11
gi|157426898 tripartite motif-containing 10 isoform 1 [Homo sapi... 66 9e-11
gi|157426896 tripartite motif-containing 10 isoform 2 [Homo sapi... 66 9e-11
gi|4508005 tripartite motif-containing 26 [Homo sapiens] 65 2e-10
gi|37622899 ring finger protein 137 [Homo sapiens] 65 2e-10
gi|223890259 midline 2 isoform 2 [Homo sapiens] 64 4e-10
gi|223890257 midline 2 isoform 1 [Homo sapiens] 64 4e-10
gi|55953112 ret finger protein 2 isoform 2 [Homo sapiens] 64 4e-10
gi|47132524 ret finger protein 2 isoform 1 [Homo sapiens] 64 4e-10
gi|16445412 ret finger protein 2 isoform 1 [Homo sapiens] 64 4e-10
gi|47132521 ret finger protein 2 isoform 1 [Homo sapiens] 64 4e-10
gi|5730009 ret finger protein [Homo sapiens] 63 7e-10
gi|62865604 tripartite motif protein 31 [Homo sapiens] 62 2e-09
gi|169202726 PREDICTED: similar to ring finger protein 18 isofor... 61 4e-09
gi|239755488 PREDICTED: similar to ring finger protein 18 isofor... 61 4e-09
gi|169203362 PREDICTED: similar to ring finger protein 18 [Homo ... 61 4e-09
>gi|153791514 tripartite motif-containing 32 [Homo sapiens]
Length = 653
Score = 1315 bits (3404), Expect = 0.0
Identities = 653/653 (100%), Positives = 653/653 (100%)
Query: 1 MAAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVR 60
MAAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVR
Sbjct: 1 MAAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVR 60
Query: 61 CPFCSKITRITSLTQLTDNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSCGLVLC 120
CPFCSKITRITSLTQLTDNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSCGLVLC
Sbjct: 61 CPFCSKITRITSLTQLTDNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSCGLVLC 120
Query: 121 EPCREADHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDLQAR 180
EPCREADHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDLQAR
Sbjct: 121 EPCREADHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDLQAR 180
Query: 181 YKAVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEEQSYLLNIAEVQAVSRCD 240
YKAVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEEQSYLLNIAEVQAVSRCD
Sbjct: 181 YKAVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEEQSYLLNIAEVQAVSRCD 240
Query: 241 YFLAKIKQADVALLEETADEEEPELTASLPRELTLQDVELLKVGHVGPLQIGQAVKKPRT 300
YFLAKIKQADVALLEETADEEEPELTASLPRELTLQDVELLKVGHVGPLQIGQAVKKPRT
Sbjct: 241 YFLAKIKQADVALLEETADEEEPELTASLPRELTLQDVELLKVGHVGPLQIGQAVKKPRT 300
Query: 301 VNVEDSWAMEATASAASTSVTFREMDMSPEEVVASPRASPAKQRGPEAASNIQQCLFLKK 360
VNVEDSWAMEATASAASTSVTFREMDMSPEEVVASPRASPAKQRGPEAASNIQQCLFLKK
Sbjct: 301 VNVEDSWAMEATASAASTSVTFREMDMSPEEVVASPRASPAKQRGPEAASNIQQCLFLKK 360
Query: 361 MGAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKGFLKEIRRSPSGIDSFVLS 420
MGAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKGFLKEIRRSPSGIDSFVLS
Sbjct: 361 MGAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKGFLKEIRRSPSGIDSFVLS 420
Query: 421 FLGADLPNLTPLSVAMNCQGLIGVTDSYDNSLKVYTLDGHCVACHRSQLSKPWGITALPS 480
FLGADLPNLTPLSVAMNCQGLIGVTDSYDNSLKVYTLDGHCVACHRSQLSKPWGITALPS
Sbjct: 421 FLGADLPNLTPLSVAMNCQGLIGVTDSYDNSLKVYTLDGHCVACHRSQLSKPWGITALPS 480
Query: 481 GQFVVTDVEGGKLWCFTVDRGSGVVKYSCLCSAVRPKFVTCDAEGTVYFTQGLGLNLENR 540
GQFVVTDVEGGKLWCFTVDRGSGVVKYSCLCSAVRPKFVTCDAEGTVYFTQGLGLNLENR
Sbjct: 481 GQFVVTDVEGGKLWCFTVDRGSGVVKYSCLCSAVRPKFVTCDAEGTVYFTQGLGLNLENR 540
Query: 541 QNEHHLEGGFSIGSVGPDGQLGRQISHFFSENEDFRCIAGMCVDARGDLIVADSSRKEIL 600
QNEHHLEGGFSIGSVGPDGQLGRQISHFFSENEDFRCIAGMCVDARGDLIVADSSRKEIL
Sbjct: 541 QNEHHLEGGFSIGSVGPDGQLGRQISHFFSENEDFRCIAGMCVDARGDLIVADSSRKEIL 600
Query: 601 HFPKGGGYSVLIREGLTCPVGIALTPKGQLLVLDCWDHCIKIYSYHLRRYSTP 653
HFPKGGGYSVLIREGLTCPVGIALTPKGQLLVLDCWDHCIKIYSYHLRRYSTP
Sbjct: 601 HFPKGGGYSVLIREGLTCPVGIALTPKGQLLVLDCWDHCIKIYSYHLRRYSTP 653
>gi|153792582 tripartite motif-containing 32 [Homo sapiens]
Length = 653
Score = 1315 bits (3404), Expect = 0.0
Identities = 653/653 (100%), Positives = 653/653 (100%)
Query: 1 MAAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVR 60
MAAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVR
Sbjct: 1 MAAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVR 60
Query: 61 CPFCSKITRITSLTQLTDNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSCGLVLC 120
CPFCSKITRITSLTQLTDNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSCGLVLC
Sbjct: 61 CPFCSKITRITSLTQLTDNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSCGLVLC 120
Query: 121 EPCREADHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDLQAR 180
EPCREADHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDLQAR
Sbjct: 121 EPCREADHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDLQAR 180
Query: 181 YKAVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEEQSYLLNIAEVQAVSRCD 240
YKAVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEEQSYLLNIAEVQAVSRCD
Sbjct: 181 YKAVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEEQSYLLNIAEVQAVSRCD 240
Query: 241 YFLAKIKQADVALLEETADEEEPELTASLPRELTLQDVELLKVGHVGPLQIGQAVKKPRT 300
YFLAKIKQADVALLEETADEEEPELTASLPRELTLQDVELLKVGHVGPLQIGQAVKKPRT
Sbjct: 241 YFLAKIKQADVALLEETADEEEPELTASLPRELTLQDVELLKVGHVGPLQIGQAVKKPRT 300
Query: 301 VNVEDSWAMEATASAASTSVTFREMDMSPEEVVASPRASPAKQRGPEAASNIQQCLFLKK 360
VNVEDSWAMEATASAASTSVTFREMDMSPEEVVASPRASPAKQRGPEAASNIQQCLFLKK
Sbjct: 301 VNVEDSWAMEATASAASTSVTFREMDMSPEEVVASPRASPAKQRGPEAASNIQQCLFLKK 360
Query: 361 MGAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKGFLKEIRRSPSGIDSFVLS 420
MGAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKGFLKEIRRSPSGIDSFVLS
Sbjct: 361 MGAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKGFLKEIRRSPSGIDSFVLS 420
Query: 421 FLGADLPNLTPLSVAMNCQGLIGVTDSYDNSLKVYTLDGHCVACHRSQLSKPWGITALPS 480
FLGADLPNLTPLSVAMNCQGLIGVTDSYDNSLKVYTLDGHCVACHRSQLSKPWGITALPS
Sbjct: 421 FLGADLPNLTPLSVAMNCQGLIGVTDSYDNSLKVYTLDGHCVACHRSQLSKPWGITALPS 480
Query: 481 GQFVVTDVEGGKLWCFTVDRGSGVVKYSCLCSAVRPKFVTCDAEGTVYFTQGLGLNLENR 540
GQFVVTDVEGGKLWCFTVDRGSGVVKYSCLCSAVRPKFVTCDAEGTVYFTQGLGLNLENR
Sbjct: 481 GQFVVTDVEGGKLWCFTVDRGSGVVKYSCLCSAVRPKFVTCDAEGTVYFTQGLGLNLENR 540
Query: 541 QNEHHLEGGFSIGSVGPDGQLGRQISHFFSENEDFRCIAGMCVDARGDLIVADSSRKEIL 600
QNEHHLEGGFSIGSVGPDGQLGRQISHFFSENEDFRCIAGMCVDARGDLIVADSSRKEIL
Sbjct: 541 QNEHHLEGGFSIGSVGPDGQLGRQISHFFSENEDFRCIAGMCVDARGDLIVADSSRKEIL 600
Query: 601 HFPKGGGYSVLIREGLTCPVGIALTPKGQLLVLDCWDHCIKIYSYHLRRYSTP 653
HFPKGGGYSVLIREGLTCPVGIALTPKGQLLVLDCWDHCIKIYSYHLRRYSTP
Sbjct: 601 HFPKGGGYSVLIREGLTCPVGIALTPKGQLLVLDCWDHCIKIYSYHLRRYSTP 653
>gi|194248081 tripartite motif-containing 2 isoform 2 [Homo sapiens]
Length = 744
Score = 117 bits (292), Expect = 4e-26
Identities = 170/765 (22%), Positives = 291/765 (38%), Gaps = 174/765 (22%)
Query: 15 REVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVRCPFCSK-------- 66
++ L C IC+E + PK+L C HT C +CL+ + + + CP C +
Sbjct: 18 KQFLICSICLERYKN----PKVLPCLHTFCERCLQNYIPAHSLTLSCPVCRQTSILPEKG 73
Query: 67 ---------ITRITSLTQLT--DNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSC 115
IT + + Q T N I++T A L C + + +C+SC
Sbjct: 74 VAALQNNFFITNLMDVLQRTPGSNAEESSILETVTAVAAGKPLSCPNHDGNVMEFYCQSC 133
Query: 116 GLVLCEPCREADHQPPGHCTLPVKEAAEERRR--------------DFGEKLTRLRELMG 161
+C C E +H H T+P+K+ E+ + + L + E++
Sbjct: 134 ETAMCRECTEGEHAE--HPTVPLKDVVEQHKASLQVQLDAVNKRLPEIDSALQFISEIIH 191
Query: 162 ELQRRKAAL--------EGVSKDLQARYKAVLQE----YGHEERRVQDEL---------A 200
+L +KA++ + + K L R +L E YG + + +Q +L
Sbjct: 192 QLTNQKASIVDDIHSTFDELQKTLNVRKSVLLMELEVNYGLKHKVLQSQLDTLLQGQESI 251
Query: 201 RSRKFFT------GSLAEVEKSNSQVVEEQSYLLN---------------IAEVQAVSRC 239
+S FT G+ EV Q+ E+ + L + I E + + +
Sbjct: 252 KSCSNFTAQALNHGTETEVLLVKKQMSEKLNELADQDFPLHPRENDQLDFIVETEGLKKS 311
Query: 240 DYFLAKIKQADVALLEETADEEEPELTA-SLPRELTL----QDVELLKVGHV-------- 286
+ L I + E A E T P +T+ +D EL K G+
Sbjct: 312 IHNLGTILTTNAVASETVATGEGLRQTIIGQPMSVTITTKDKDGELCKTGNAYLTAELST 371
Query: 287 --GPLQIGQAVKKPR-------TVNVEDSWAM------EATASAASTSVTFREMDMSP-- 329
G + G+ + TV E + + + + R D+SP
Sbjct: 372 PDGSVADGEILDNKNGTYEFLYTVQKEGDFTLSLRLYDQHIRGSPFKLKVIRSADVSPTT 431
Query: 330 ---EEVVASPRASPAKQR-----------GPEAASNIQQCLFLKKMGAKGSTPGMFNLPV 375
+ V SP + KQ+ G + I+ L + +G KG G F
Sbjct: 432 EGVKRRVKSPGSGHVKQKAVKRPASMYSTGKRKENPIEDDLIFR-VGTKGRNKGEFTNLQ 490
Query: 376 SLYVTSQGEVLVADRGNYRIQVFTRKGFLKE---IR-RSPSGIDSFVLSFLGADLPNLTP 431
+ ++ G++L+AD N +Q+F+ G K IR RSP + P
Sbjct: 491 GVAASTNGKILIADSNNQCVQIFSNDGQFKSRFGIRGRSPGQLQR--------------P 536
Query: 432 LSVAMNCQGLIGVTDSYDNS-LKVYTLDGHC-VACHRSQLSKPWGITALPSGQFVVTDVE 489
VA++ G I + D YDN + +++ DG +L P G++ +G +V D +
Sbjct: 537 TGVAVHPSGDIIIAD-YDNKWVSIFSSDGKFKTKIGSGKLMGPKGVSVDRNGHIIVVDNK 595
Query: 490 GGKLWCFTVDRGSGVVKYSCLCSAVR----PKFVTCDAEGTVYFTQ--GLGLNLENRQNE 543
++ F + G V ++ + R P F ++ + T + + N++ E
Sbjct: 596 ACCVFIFQPN-GKIVTRFGSRGNGDRQFAGPHFAAVNSNNEIIITDFHNHSVKVFNQEGE 654
Query: 544 HHLEGGFSIGSVGPDGQLGRQISHFFSENEDFRCIAGMCVDARGDLIVADSSRKEILHFP 603
L+ G +G+ N F G+ VD+ G++IVAD I F
Sbjct: 655 FMLK-------FGSNGE----------GNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFD 697
Query: 604 KGGGYSVLIR---EGLTCPVGIALTPKGQLLVLDCWDHCIKIYSY 645
G + I + L P G+ALT G ++V D +HC K+Y Y
Sbjct: 698 GSGSFLSYINTSADPLYGPQGLALTSDGHVVVADSGNHCFKVYRY 742
>gi|194248079 tripartite motif-containing 2 isoform 1 [Homo sapiens]
Length = 771
Score = 117 bits (292), Expect = 4e-26
Identities = 170/765 (22%), Positives = 291/765 (38%), Gaps = 174/765 (22%)
Query: 15 REVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVRCPFCSK-------- 66
++ L C IC+E + PK+L C HT C +CL+ + + + CP C +
Sbjct: 45 KQFLICSICLERYKN----PKVLPCLHTFCERCLQNYIPAHSLTLSCPVCRQTSILPEKG 100
Query: 67 ---------ITRITSLTQLT--DNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSC 115
IT + + Q T N I++T A L C + + +C+SC
Sbjct: 101 VAALQNNFFITNLMDVLQRTPGSNAEESSILETVTAVAAGKPLSCPNHDGNVMEFYCQSC 160
Query: 116 GLVLCEPCREADHQPPGHCTLPVKEAAEERRR--------------DFGEKLTRLRELMG 161
+C C E +H H T+P+K+ E+ + + L + E++
Sbjct: 161 ETAMCRECTEGEHAE--HPTVPLKDVVEQHKASLQVQLDAVNKRLPEIDSALQFISEIIH 218
Query: 162 ELQRRKAAL--------EGVSKDLQARYKAVLQE----YGHEERRVQDEL---------A 200
+L +KA++ + + K L R +L E YG + + +Q +L
Sbjct: 219 QLTNQKASIVDDIHSTFDELQKTLNVRKSVLLMELEVNYGLKHKVLQSQLDTLLQGQESI 278
Query: 201 RSRKFFT------GSLAEVEKSNSQVVEEQSYLLN---------------IAEVQAVSRC 239
+S FT G+ EV Q+ E+ + L + I E + + +
Sbjct: 279 KSCSNFTAQALNHGTETEVLLVKKQMSEKLNELADQDFPLHPRENDQLDFIVETEGLKKS 338
Query: 240 DYFLAKIKQADVALLEETADEEEPELTA-SLPRELTL----QDVELLKVGHV-------- 286
+ L I + E A E T P +T+ +D EL K G+
Sbjct: 339 IHNLGTILTTNAVASETVATGEGLRQTIIGQPMSVTITTKDKDGELCKTGNAYLTAELST 398
Query: 287 --GPLQIGQAVKKPR-------TVNVEDSWAM------EATASAASTSVTFREMDMSP-- 329
G + G+ + TV E + + + + R D+SP
Sbjct: 399 PDGSVADGEILDNKNGTYEFLYTVQKEGDFTLSLRLYDQHIRGSPFKLKVIRSADVSPTT 458
Query: 330 ---EEVVASPRASPAKQR-----------GPEAASNIQQCLFLKKMGAKGSTPGMFNLPV 375
+ V SP + KQ+ G + I+ L + +G KG G F
Sbjct: 459 EGVKRRVKSPGSGHVKQKAVKRPASMYSTGKRKENPIEDDLIFR-VGTKGRNKGEFTNLQ 517
Query: 376 SLYVTSQGEVLVADRGNYRIQVFTRKGFLKE---IR-RSPSGIDSFVLSFLGADLPNLTP 431
+ ++ G++L+AD N +Q+F+ G K IR RSP + P
Sbjct: 518 GVAASTNGKILIADSNNQCVQIFSNDGQFKSRFGIRGRSPGQLQR--------------P 563
Query: 432 LSVAMNCQGLIGVTDSYDNS-LKVYTLDGHC-VACHRSQLSKPWGITALPSGQFVVTDVE 489
VA++ G I + D YDN + +++ DG +L P G++ +G +V D +
Sbjct: 564 TGVAVHPSGDIIIAD-YDNKWVSIFSSDGKFKTKIGSGKLMGPKGVSVDRNGHIIVVDNK 622
Query: 490 GGKLWCFTVDRGSGVVKYSCLCSAVR----PKFVTCDAEGTVYFTQ--GLGLNLENRQNE 543
++ F + G V ++ + R P F ++ + T + + N++ E
Sbjct: 623 ACCVFIFQPN-GKIVTRFGSRGNGDRQFAGPHFAAVNSNNEIIITDFHNHSVKVFNQEGE 681
Query: 544 HHLEGGFSIGSVGPDGQLGRQISHFFSENEDFRCIAGMCVDARGDLIVADSSRKEILHFP 603
L+ G +G+ N F G+ VD+ G++IVAD I F
Sbjct: 682 FMLK-------FGSNGE----------GNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFD 724
Query: 604 KGGGYSVLIR---EGLTCPVGIALTPKGQLLVLDCWDHCIKIYSY 645
G + I + L P G+ALT G ++V D +HC K+Y Y
Sbjct: 725 GSGSFLSYINTSADPLYGPQGLALTSDGHVVVADSGNHCFKVYRY 769
>gi|84993742 tripartite motif-containing 71 [Homo sapiens]
Length = 868
Score = 73.6 bits (179), Expect = 6e-13
Identities = 77/301 (25%), Positives = 123/301 (40%), Gaps = 48/301 (15%)
Query: 362 GAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKGFLKEIRRSPSGIDSFVLSF 421
G++G + G P + V +G ++VADR N RIQVF P G
Sbjct: 597 GSEGDSDGKLCRPWGVSVDKEGYIIVADRSNNRIQVF-----------KPCGAFHHKFGT 645
Query: 422 LGADLPNL-TPLSVAMNCQGLIGVTDSYDNSLKVYTLDGHCV------ACHRSQLSKPWG 474
LG+ P VA + I V D ++ ++++T +G + Q + PW
Sbjct: 646 LGSRPGQFDRPAGVACDASRRIVVADKDNHRIQIFTFEGQFLLKFGEKGTKNGQFNYPWD 705
Query: 475 ITALPSGQFVVTDVEGGKLWCFTVDRGSGVVKYSCLCSAVR----PKFVTCDAEGTVYFT 530
+ G+ +V+D ++ F D G + KY + + P+ V + EG + T
Sbjct: 706 VAVNSEGKILVSDTRNHRIQLFGPD-GVFLNKYGFEGALWKHFDSPRGVAFNHEGHLVVT 764
Query: 531 QGLGLNLENRQNEHHLEGGFSIGSVGPDGQLGRQISHFFSENEDFRCIAGMCVDARGDLI 590
N H L + PD Q R + + N F G+ VD G +I
Sbjct: 765 D---------FNNHRLL------VIHPDCQSARFLGSEGTGNGQFLRPQGVAVDQEGRII 809
Query: 591 VADSSRKEILHFPKGGGYSVLIREG--------LTCPVGIALTPKGQLLVLDCWDHCIKI 642
VADS + F G S L + G + P GIA+TP G ++V+D ++ I +
Sbjct: 810 VADSRNHRVQMFESNG--SFLCKFGAQGSGFGQMDRPSGIAITPDGMIVVVDFGNNRILV 867
Query: 643 Y 643
+
Sbjct: 868 F 868
Score = 58.9 bits (141), Expect = 1e-08
Identities = 51/182 (28%), Positives = 77/182 (42%), Gaps = 23/182 (12%)
Query: 357 FLKKMGAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKGFLKEIRRSPSGIDS 416
FL K G KG+ G FN P + V S+G++LV+D N+RIQ+F P G+
Sbjct: 686 FLLKFGEKGTKNGQFNYPWDVAVNSEGKILVSDTRNHRIQLF-----------GPDGVFL 734
Query: 417 FVLSFLGADLPNL-TPLSVAMNCQGLIGVTDSYDNSLKVYTLDGHCV------ACHRSQL 469
F GA + +P VA N +G + VTD ++ L V D Q
Sbjct: 735 NKYGFEGALWKHFDSPRGVAFNHEGHLVVTDFNNHRLLVIHPDCQSARFLGSEGTGNGQF 794
Query: 470 SKPWGITALPSGQFVVTDVEGGKLWCFTVDRGSGVVKYSCLCSAV----RPKFVTCDAEG 525
+P G+ G+ +V D ++ F GS + K+ S RP + +G
Sbjct: 795 LRPQGVAVDQEGRIIVADSRNHRVQMFE-SNGSFLCKFGAQGSGFGQMDRPSGIAITPDG 853
Query: 526 TV 527
+
Sbjct: 854 MI 855
Score = 42.4 bits (98), Expect = 0.001
Identities = 37/151 (24%), Positives = 65/151 (43%), Gaps = 24/151 (15%)
Query: 356 LFLKKMGAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKGFLKEIRRSPSGID 415
+FL K G +G+ F+ P + +G ++V D N+R+ V D
Sbjct: 732 VFLNKYGFEGALWKHFDSPRGVAFNHEGHLVVTDFNNHRLLVIHP--------------D 777
Query: 416 SFVLSFLGADLPN----LTPLSVAMNCQGLIGVTDSYDNSLKVYTLDGHCVACHRS---- 467
FLG++ L P VA++ +G I V DS ++ ++++ +G + +
Sbjct: 778 CQSARFLGSEGTGNGQFLRPQGVAVDQEGRIIVADSRNHRVQMFESNGSFLCKFGAQGSG 837
Query: 468 --QLSKPWGITALPSGQFVVTDVEGGKLWCF 496
Q+ +P GI P G VV D ++ F
Sbjct: 838 FGQMDRPSGIAITPDGMIVVVDFGNNRILVF 868
Score = 42.0 bits (97), Expect = 0.002
Identities = 28/102 (27%), Positives = 47/102 (46%), Gaps = 12/102 (11%)
Query: 355 CLFLKKMGAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKG-FLKEIRRSPSG 413
C + +G++G+ G F P + V +G ++VAD N+R+Q+F G FL + SG
Sbjct: 778 CQSARFLGSEGTGNGQFLRPQGVAVDQEGRIIVADSRNHRVQMFESNGSFLCKFGAQGSG 837
Query: 414 IDSFVLSFLGADLPNLTPLSVAMNCQGLIGVTDSYDNSLKVY 455
P +A+ G+I V D +N + V+
Sbjct: 838 FGQMD-----------RPSGIAITPDGMIVVVDFGNNRILVF 868
>gi|32454739 tripartite motif-containing 3 [Homo sapiens]
Length = 744
Score = 72.4 bits (176), Expect = 1e-12
Identities = 78/299 (26%), Positives = 123/299 (41%), Gaps = 44/299 (14%)
Query: 360 KMGAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKGFLK---EIR-RSPSGID 415
++G++G G F + S G ++VAD N IQVF+ +G K +R RSP +
Sbjct: 475 RVGSRGREKGEFTNLQGVSAASSGRIVVADSNNQCIQVFSNEGQFKFRFGVRGRSPGQLQ 534
Query: 416 SFVLSFLGADLPNLTPLSVAMNCQGLIGVTDSYDNS-LKVYTLDGHC-VACHRSQLSKPW 473
P VA++ G I V D YDN + +++ +G +L P
Sbjct: 535 R--------------PTGVAVDTNGDIIVAD-YDNRWVSIFSPEGKFKTKIGAGRLMGPK 579
Query: 474 GITALPSGQFVVTDVEGGKLWCFTVDRGSGVVKYSCLCSAVR----PKFVTCDAEGTVYF 529
G+ +G +V D + ++ F + G V ++ + R P FV + + +
Sbjct: 580 GVAVDRNGHIIVVDNKSCCVFTFQPN-GKLVGRFGGRGATDRHFAGPHFVAVNNKNEIVV 638
Query: 530 TQGLGLNLENRQNEHHLEGGFSIGSVGPDGQLGRQISHFFSENEDFRCIAGMCVDARGDL 589
T + H S+ DG+ + N F G+ VD+ G++
Sbjct: 639 T------------DFH---NHSVKVYSADGEFLFKFGSHGEGNGQFNAPTGVAVDSNGNI 683
Query: 590 IVADSSRKEILHFPKGGGYSVLIR---EGLTCPVGIALTPKGQLLVLDCWDHCIKIYSY 645
IVAD I F G + I E L P G+ALT G ++V D +HC K Y Y
Sbjct: 684 IVADWGNSRIQVFDSSGSFLSYINTSAEPLYGPQGLALTSDGHVVVADAGNHCFKAYRY 742
Score = 70.1 bits (170), Expect = 6e-12
Identities = 74/344 (21%), Positives = 135/344 (39%), Gaps = 41/344 (11%)
Query: 15 REVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVRCPFC--SKITRITS 72
++ L C IC++ + PK+L C HT C +CL+ + + + CP C + I
Sbjct: 17 KQFLVCSICLDRYQ----CPKVLPCLHTFCERCLQNYIPAQSLTLSCPVCRQTSILPEQG 72
Query: 73 LTQLTDNLTVLKII--------------DTAGLSEAVGL-LMCRSCGRRLPRQFCRSCGL 117
++ L +N + ++ D LS G L C + + +C +C
Sbjct: 73 VSALQNNFFISSLMEAMQQAPDGAHDPEDPHPLSVVAGRPLSCPNHEGKTMEFYCEACET 132
Query: 118 VLCEPCREADHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDL 177
+C CR +H+ H T+ +++ E+ + +L +R + +L A + G+S+ L
Sbjct: 133 AMCGECRAGEHRE--HGTVLLRDVVEQHKAALQRQLEAVRGRLPQLSAAIALVGGISQQL 190
Query: 178 QARYKAVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEEQSYLLNIAEVQAVS 237
Q R L + ++ L + ++ L + + +V++ Q L + S
Sbjct: 191 QERKAEALAQISAAFEDLEQALQQRKQALVSDLETICGAKQKVLQSQLDTLRQGQEHIGS 250
Query: 238 RCDY--------------FLAKIKQADVALLEETADEEEPELTASLPRELTLQ-DVELLK 282
C + + K + +A L A E P A L EL L+ D
Sbjct: 251 SCSFAEQALRLGSAPEVLLVRKHMRERLAALAAQAFPERPHENAQL--ELVLEVDGLRRS 308
Query: 283 VGHVGPLQIGQAVKKPRTVNVEDSWAMEATASAASTSVTFREMD 326
V ++G L A TV + AS +VT ++ D
Sbjct: 309 VLNLGALLTTSATAH-ETVATGEGLRQALVGQPASLTVTTKDKD 351
Score = 52.0 bits (123), Expect = 2e-06
Identities = 35/100 (35%), Positives = 45/100 (45%), Gaps = 15/100 (15%)
Query: 357 FLKKMGAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKG-FLKEIRRSPSGID 415
FL K G+ G G FN P + V S G ++VAD GN RIQVF G FL I S
Sbjct: 655 FLFKFGSHGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDSSGSFLSYINTSAE--- 711
Query: 416 SFVLSFLGADLPNLTPLSVAMNCQGLIGVTDSYDNSLKVY 455
P P +A+ G + V D+ ++ K Y
Sbjct: 712 -----------PLYGPQGLALTSDGHVVVADAGNHCFKAY 740
Score = 45.4 bits (106), Expect = 2e-04
Identities = 42/178 (23%), Positives = 70/178 (39%), Gaps = 38/178 (21%)
Query: 357 FLKKMGAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKGFLKE-----IRRSP 411
F + G +G +PG P + V + G+++VAD N + +F+ +G K P
Sbjct: 519 FKFRFGVRGRSPGQLQRPTGVAVDTNGDIIVADYDNRWVSIFSPEGKFKTKIGAGRLMGP 578
Query: 412 SGI--------------DSFVLSFL-------------GADLPNLTPLSVAMNCQGLIGV 444
G+ V +F D P VA+N + I V
Sbjct: 579 KGVAVDRNGHIIVVDNKSCCVFTFQPNGKLVGRFGGRGATDRHFAGPHFVAVNNKNEIVV 638
Query: 445 TDSYDNSLKVYTLDGHCV---ACH---RSQLSKPWGITALPSGQFVVTDVEGGKLWCF 496
TD +++S+KVY+ DG + H Q + P G+ +G +V D ++ F
Sbjct: 639 TDFHNHSVKVYSADGEFLFKFGSHGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVF 696
>gi|32454737 tripartite motif-containing 3 [Homo sapiens]
Length = 744
Score = 72.4 bits (176), Expect = 1e-12
Identities = 78/299 (26%), Positives = 123/299 (41%), Gaps = 44/299 (14%)
Query: 360 KMGAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKGFLK---EIR-RSPSGID 415
++G++G G F + S G ++VAD N IQVF+ +G K +R RSP +
Sbjct: 475 RVGSRGREKGEFTNLQGVSAASSGRIVVADSNNQCIQVFSNEGQFKFRFGVRGRSPGQLQ 534
Query: 416 SFVLSFLGADLPNLTPLSVAMNCQGLIGVTDSYDNS-LKVYTLDGHC-VACHRSQLSKPW 473
P VA++ G I V D YDN + +++ +G +L P
Sbjct: 535 R--------------PTGVAVDTNGDIIVAD-YDNRWVSIFSPEGKFKTKIGAGRLMGPK 579
Query: 474 GITALPSGQFVVTDVEGGKLWCFTVDRGSGVVKYSCLCSAVR----PKFVTCDAEGTVYF 529
G+ +G +V D + ++ F + G V ++ + R P FV + + +
Sbjct: 580 GVAVDRNGHIIVVDNKSCCVFTFQPN-GKLVGRFGGRGATDRHFAGPHFVAVNNKNEIVV 638
Query: 530 TQGLGLNLENRQNEHHLEGGFSIGSVGPDGQLGRQISHFFSENEDFRCIAGMCVDARGDL 589
T + H S+ DG+ + N F G+ VD+ G++
Sbjct: 639 T------------DFH---NHSVKVYSADGEFLFKFGSHGEGNGQFNAPTGVAVDSNGNI 683
Query: 590 IVADSSRKEILHFPKGGGYSVLIR---EGLTCPVGIALTPKGQLLVLDCWDHCIKIYSY 645
IVAD I F G + I E L P G+ALT G ++V D +HC K Y Y
Sbjct: 684 IVADWGNSRIQVFDSSGSFLSYINTSAEPLYGPQGLALTSDGHVVVADAGNHCFKAYRY 742
Score = 70.1 bits (170), Expect = 6e-12
Identities = 74/344 (21%), Positives = 135/344 (39%), Gaps = 41/344 (11%)
Query: 15 REVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVRCPFC--SKITRITS 72
++ L C IC++ + PK+L C HT C +CL+ + + + CP C + I
Sbjct: 17 KQFLVCSICLDRYQ----CPKVLPCLHTFCERCLQNYIPAQSLTLSCPVCRQTSILPEQG 72
Query: 73 LTQLTDNLTVLKII--------------DTAGLSEAVGL-LMCRSCGRRLPRQFCRSCGL 117
++ L +N + ++ D LS G L C + + +C +C
Sbjct: 73 VSALQNNFFISSLMEAMQQAPDGAHDPEDPHPLSVVAGRPLSCPNHEGKTMEFYCEACET 132
Query: 118 VLCEPCREADHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDL 177
+C CR +H+ H T+ +++ E+ + +L +R + +L A + G+S+ L
Sbjct: 133 AMCGECRAGEHRE--HGTVLLRDVVEQHKAALQRQLEAVRGRLPQLSAAIALVGGISQQL 190
Query: 178 QARYKAVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEEQSYLLNIAEVQAVS 237
Q R L + ++ L + ++ L + + +V++ Q L + S
Sbjct: 191 QERKAEALAQISAAFEDLEQALQQRKQALVSDLETICGAKQKVLQSQLDTLRQGQEHIGS 250
Query: 238 RCDY--------------FLAKIKQADVALLEETADEEEPELTASLPRELTLQ-DVELLK 282
C + + K + +A L A E P A L EL L+ D
Sbjct: 251 SCSFAEQALRLGSAPEVLLVRKHMRERLAALAAQAFPERPHENAQL--ELVLEVDGLRRS 308
Query: 283 VGHVGPLQIGQAVKKPRTVNVEDSWAMEATASAASTSVTFREMD 326
V ++G L A TV + AS +VT ++ D
Sbjct: 309 VLNLGALLTTSATAH-ETVATGEGLRQALVGQPASLTVTTKDKD 351
Score = 52.0 bits (123), Expect = 2e-06
Identities = 35/100 (35%), Positives = 45/100 (45%), Gaps = 15/100 (15%)
Query: 357 FLKKMGAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKG-FLKEIRRSPSGID 415
FL K G+ G G FN P + V S G ++VAD GN RIQVF G FL I S
Sbjct: 655 FLFKFGSHGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDSSGSFLSYINTSAE--- 711
Query: 416 SFVLSFLGADLPNLTPLSVAMNCQGLIGVTDSYDNSLKVY 455
P P +A+ G + V D+ ++ K Y
Sbjct: 712 -----------PLYGPQGLALTSDGHVVVADAGNHCFKAY 740
Score = 45.4 bits (106), Expect = 2e-04
Identities = 42/178 (23%), Positives = 70/178 (39%), Gaps = 38/178 (21%)
Query: 357 FLKKMGAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKGFLKE-----IRRSP 411
F + G +G +PG P + V + G+++VAD N + +F+ +G K P
Sbjct: 519 FKFRFGVRGRSPGQLQRPTGVAVDTNGDIIVADYDNRWVSIFSPEGKFKTKIGAGRLMGP 578
Query: 412 SGI--------------DSFVLSFL-------------GADLPNLTPLSVAMNCQGLIGV 444
G+ V +F D P VA+N + I V
Sbjct: 579 KGVAVDRNGHIIVVDNKSCCVFTFQPNGKLVGRFGGRGATDRHFAGPHFVAVNNKNEIVV 638
Query: 445 TDSYDNSLKVYTLDGHCV---ACH---RSQLSKPWGITALPSGQFVVTDVEGGKLWCF 496
TD +++S+KVY+ DG + H Q + P G+ +G +V D ++ F
Sbjct: 639 TDFHNHSVKVYSADGEFLFKFGSHGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVF 696
>gi|60593056 hypothetical protein LOC283948 [Homo sapiens]
Length = 123
Score = 72.4 bits (176), Expect = 1e-12
Identities = 37/87 (42%), Positives = 52/87 (59%), Gaps = 6/87 (6%)
Query: 557 PDGQLGRQISHFFSENEDFRCIAGMCVDARGDLIVADSSRKEILHFPKGGGYSVLIREGL 616
P G LG H F C AG+C ++ G++IVAD R+++ FP+ G L+ EGL
Sbjct: 36 PLGSLGGWTGHTFG------CPAGICSNSEGNVIVADEQRRQVTLFPRAGPPICLVSEGL 89
Query: 617 TCPVGIALTPKGQLLVLDCWDHCIKIY 643
P+G+A P+GQLLV D D+ IK+Y
Sbjct: 90 GQPLGVACAPQGQLLVADAKDNSIKVY 116
Score = 37.7 bits (86), Expect = 0.034
Identities = 30/91 (32%), Positives = 40/91 (43%), Gaps = 16/91 (17%)
Query: 365 GSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKGFLKEIRRSPSGIDSFVLSFLGA 424
G T F P + S+G V+VAD ++ +F R G P + S L
Sbjct: 42 GWTGHTFGCPAGICSNSEGNVIVADEQRRQVTLFPRAG-------PPICLVSEGLG---- 90
Query: 425 DLPNLTPLSVAMNCQGLIGVTDSYDNSLKVY 455
PL VA QG + V D+ DNS+KVY
Sbjct: 91 -----QPLGVACAPQGQLLVADAKDNSIKVY 116
Score = 31.2 bits (69), Expect = 3.1
Identities = 14/63 (22%), Positives = 26/63 (41%)
Query: 431 PLSVAMNCQGLIGVTDSYDNSLKVYTLDGHCVACHRSQLSKPWGITALPSGQFVVTDVEG 490
P + N +G + V D + ++ G + L +P G+ P GQ +V D +
Sbjct: 51 PAGICSNSEGNVIVADEQRRQVTLFPRAGPPICLVSEGLGQPLGVACAPQGQLLVADAKD 110
Query: 491 GKL 493
+
Sbjct: 111 NSI 113
>gi|15208660 tripartite motif protein 21 [Homo sapiens]
Length = 475
Score = 71.6 bits (174), Expect = 2e-12
Identities = 75/299 (25%), Positives = 129/299 (43%), Gaps = 35/299 (11%)
Query: 6 ASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVRCPFCS 65
AS L + E + CPIC++ F E P + CGH+ C++C+ ++ G CP C
Sbjct: 2 ASAARLTMMWEEVTCPICLDPFVE----PVSIECGHSFCQECISQV--GKGGGSVCPVCR 55
Query: 66 KITRITSL---TQLTDNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSCGLVLCEP 122
+ + +L QL + + LK I G C G RL FC G LC
Sbjct: 56 QRFLLKNLRPNRQLANMVNNLKEISQEAREGTQG-ERCAVHGERL-HLFCEKDGKALCWV 113
Query: 123 CREADHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDLQARYK 182
C ++ + H +P++EAA+E + +L+ +GEL+R++ E + ++ +
Sbjct: 114 CAQS-RKHRDHAMVPLEEAAQEYQE-------KLQVALGELRRKQELAEKLEVEIAIKRA 165
Query: 183 AVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVE----EQSYLLNIAEVQAVSR 238
+ ++ R+ E + + F L E E+ Q +E EQ +L E + +
Sbjct: 166 DWKKTVETQKSRIHAEFVQQKNF----LVEEEQRQLQELEKDEREQLRILGEKEAKLAQQ 221
Query: 239 CDYFLAKIKQAD-------VALLEETADEEEPELTASLPRELTLQDVELLKVGHVGPLQ 290
I + D + LL+E E + +L ++L + EL V HV L+
Sbjct: 222 SQALQELISELDRRCHSSALELLQEVIIVLERSESWNL-KDLDITSPELRSVCHVPGLK 279
>gi|157743261 tripartite motif-containing 75 [Homo sapiens]
Length = 468
Score = 70.9 bits (172), Expect = 4e-12
Identities = 69/283 (24%), Positives = 121/283 (42%), Gaps = 35/283 (12%)
Query: 1 MAAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVR 60
MA AAA L L+ +C IC++ ++ P + CGH CR C+++
Sbjct: 1 MAVAAA----LTGLQAEAKCSICLDYLSD----PVTIECGHNFCRSCIQQSWLDLQELFP 52
Query: 61 CPFCSKITR---ITSLTQLTDNLTVLKIIDT--AGLSEAVGLLMCRSCGRRLPRQFCRSC 115
CP C + S TQL + + K++ + + + +C + L FC+
Sbjct: 53 CPVCRHQCQEGHFRSNTQLGRMIEIAKLLQSTKSNKRKQEETTLCEKHNQPLS-VFCKED 111
Query: 116 GLVLCEPCREA-DHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVS 174
+VLC C + DHQ GH P+++AA R+ F + L++ + +LQ+ +
Sbjct: 112 LMVLCPLCTQPPDHQ--GHHVRPIEKAAIHYRKRFCSYIQPLKKQLADLQKLISTQSKKP 169
Query: 175 KDLQARYKAVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEE----------- 223
+L+ + QE E + L R ++ LAE EK N Q +
Sbjct: 170 LELREMVENQRQELSSEFEHLNQFLDREQQAVLSRLAEEEKDNQQKLSANITAFSNYSAT 229
Query: 224 -QSYLLNIAEVQAVSRCDYFLAKIKQADVALLEETADEEEPEL 265
+S L + E+ +S + L++IK + E+ +E P +
Sbjct: 230 LKSQLSKVVELSELSELE-LLSQIK-----IFYESENESSPSI 266
>gi|209862805 SPRY domain containing 5 [Homo sapiens]
Length = 452
Score = 69.7 bits (169), Expect = 8e-12
Identities = 77/282 (27%), Positives = 121/282 (42%), Gaps = 40/282 (14%)
Query: 11 LDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVRCPFCSKITRI 70
L + L CPICM F L P + CGH+ CR CL + +C C K TR
Sbjct: 6 LQVFQRALTCPICMNYF----LDPVTIDCGHSFCRPCLYLNWQDTAVLAQCSECKKTTRQ 61
Query: 71 TSLTQLTDNLTVLKIIDTAGLSEAVGLLMCRS-----CG--RRLPRQFCRSCGLVLCEPC 123
+L T + + + A ++ L S CG R + FC +LC PC
Sbjct: 62 RNLN------TDICLKNMAFIARKASLRQFLSSEEQICGMHRETKKMFCEVDKSLLCLPC 115
Query: 124 REA-DHQPPGHCTLPVKEAAEERRRDFGEKL--------TRLRELMGELQRRKAALEGVS 174
+ +H+ HC P++ AAEERR + +K+ LR L E R + + VS
Sbjct: 116 SNSQEHRNHIHC--PIEWAAEERREELLKKMQSLWEKACENLRNLNMETTRTRCWKDYVS 173
Query: 175 ---KDLQARYKAVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEEQSYLLNIA 231
+ ++A Y+ + + HEE Q L R RK ++ +S +++ + L +
Sbjct: 174 LRIEAIRAEYQK-MPAFLHEEE--QHHLERLRKEGEDIFQQLNESKARMEHSRELLRGMY 230
Query: 232 E--VQAVSRCDYFLAK----IKQADVALLEETADEEEPELTA 267
E Q + D L + I +LL + ++ PEL+A
Sbjct: 231 EDLKQMCHKADVELLQAFGDILHRYESLLLQVSEPVNPELSA 272
>gi|27436877 tripartite motif-containing 59 [Homo sapiens]
Length = 403
Score = 68.6 bits (166), Expect = 2e-11
Identities = 86/344 (25%), Positives = 147/344 (42%), Gaps = 58/344 (16%)
Query: 16 EVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSIN---------GVRCPFCSK 66
E L CPIC F + P++L C HT CR CLE +L +S N ++CP C
Sbjct: 6 EELTCPICYSIFED----PRVLPCSHTFCRNCLENILQASGNFYIWRPLRIPLKCPNCRS 61
Query: 67 ITRI--TSLTQLTDNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSCGLVLCEPCR 124
IT I T + L N + II+ + ++ C R+ +C ++C C
Sbjct: 62 ITEIAPTGIESLPVNFALRAIIEKYQQEDHPDIVTCPEHYRQPLNVYCLLDKKLVCGHCL 121
Query: 125 EADHQPPGHCTLPVKEAAEERRRDFGEKL---------TRLRELMGELQRRKAALEGVSK 175
Q GH + ++A + +D +KL T L L+ +L+ +K+ E K
Sbjct: 122 TIG-QHHGH-PIDDLQSAYLKEKDTPQKLLEQLTDTHWTDLTHLIEKLKEQKSHSE---K 176
Query: 176 DLQARYKAVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEEQSYLLNIAEVQA 235
+Q +AVLQ + + + D L + +K F +L +V L+N
Sbjct: 177 MIQGDKEAVLQYF----KELNDTLEQKKKSFLTALCDV-----------GNLINQEYTPQ 221
Query: 236 VSRCDYFLAKIKQADVALLEETAD-EEEPELTASLPRELTLQDVELLK---VGHVGPLQI 291
+ R + +I++ + L+ T +EE L + Q V++LK + V P++I
Sbjct: 222 IER----MKEIREQQLELMALTISLQEESPLKFLEKVDDVRQHVQILKQRPLPEVQPVEI 277
Query: 292 GQAVKKPRTVNVEDSWAMEATASAASTSVTFREMDMSPEEVVAS 335
V K +++ W+ T +V +M +SP+ + S
Sbjct: 278 YPRVSK----ILKEEWS--RTEIGQIKNVLIPKMKISPKRMSCS 315
>gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens]
Length = 488
Score = 67.4 bits (163), Expect = 4e-11
Identities = 53/216 (24%), Positives = 96/216 (44%), Gaps = 12/216 (5%)
Query: 14 LREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVR----CPFCSKITR 69
+RE + CPIC+E TE P + CGH+ C+ C+ S+ G CP C +
Sbjct: 9 IREEVTCPICLELLTE----PLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQ 64
Query: 70 ITSLTQLTDNLTVLKIIDTA--GLSEAVGLLMCRSCGRRLPRQFCRSCGLVLCEPCREAD 127
+L +++ + G + + ++C G +L + FC+ G V+C C E
Sbjct: 65 PGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKL-QLFCQEDGKVICWLC-ERS 122
Query: 128 HQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDLQARYKAVLQE 187
+ GH T V+E A+E + F E L +L+ E ++ A + + + +
Sbjct: 123 QEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCR 182
Query: 188 YGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEE 223
E ++++ L R + L + EK +++EE
Sbjct: 183 IQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEE 218
>gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens]
Length = 516
Score = 67.4 bits (163), Expect = 4e-11
Identities = 53/216 (24%), Positives = 96/216 (44%), Gaps = 12/216 (5%)
Query: 14 LREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVR----CPFCSKITR 69
+RE + CPIC+E TE P + CGH+ C+ C+ S+ G CP C +
Sbjct: 37 IREEVTCPICLELLTE----PLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQ 92
Query: 70 ITSLTQLTDNLTVLKIIDTA--GLSEAVGLLMCRSCGRRLPRQFCRSCGLVLCEPCREAD 127
+L +++ + G + + ++C G +L + FC+ G V+C C E
Sbjct: 93 PGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKL-QLFCQEDGKVICWLC-ERS 150
Query: 128 HQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDLQARYKAVLQE 187
+ GH T V+E A+E + F E L +L+ E ++ A + + + +
Sbjct: 151 QEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCR 210
Query: 188 YGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEE 223
E ++++ L R + L + EK +++EE
Sbjct: 211 IQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEE 246
>gi|51477690 tripartite motif-containing 6 and tripartite
motif-containing 34 [Homo sapiens]
Length = 842
Score = 67.4 bits (163), Expect = 4e-11
Identities = 53/216 (24%), Positives = 96/216 (44%), Gaps = 12/216 (5%)
Query: 14 LREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVR----CPFCSKITR 69
+RE + CPIC+E TE P + CGH+ C+ C+ S+ G CP C +
Sbjct: 37 IREEVTCPICLELLTE----PLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQ 92
Query: 70 ITSLTQLTDNLTVLKIIDTA--GLSEAVGLLMCRSCGRRLPRQFCRSCGLVLCEPCREAD 127
+L +++ + G + + ++C G +L + FC+ G V+C C E
Sbjct: 93 PGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKL-QLFCQEDGKVICWLC-ERS 150
Query: 128 HQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDLQARYKAVLQE 187
+ GH T V+E A+E + F E L +L+ E ++ A + + + +
Sbjct: 151 QEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCR 210
Query: 188 YGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEE 223
E ++++ L R + L + EK +++EE
Sbjct: 211 IQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEE 246
Score = 59.7 bits (143), Expect = 8e-09
Identities = 59/238 (24%), Positives = 102/238 (42%), Gaps = 31/238 (13%)
Query: 2 AAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCL---EKLLASSING 58
++A AS + L+ EV CPIC+E TE P L CGH++CR C+ K +S+ G
Sbjct: 352 SSAMASKILLNVQEEVT-CPICLELLTE----PLSLDCGHSLCRACITVSNKEAVTSMGG 406
Query: 59 -VRCPFC------SKITRITSLTQLTDNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQF 111
CP C + L + + L +K+ G +C G +L F
Sbjct: 407 KSSCPVCGISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRD----LCDHHGEKL-LLF 461
Query: 112 CRSCGLVLCEPCREADHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALE 171
C+ V+C C E + GH T+ +E F E +L+ ++ L++ + E
Sbjct: 462 CKEDRKVICWLC-ERSQEHRGHHTVLTEEV-------FKECQEKLQAVLKRLKKEEEEAE 513
Query: 172 GVSKDLQARYKAVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEEQSYLLN 229
+ D++ + + E +R+Q E + R E ++ ++ EE+ L+
Sbjct: 514 KLEADIREEKTSWKYQVQTERQRIQTEFDQLRSILNN---EEQRELQRLEEEEKKTLD 568
>gi|157426898 tripartite motif-containing 10 isoform 1 [Homo
sapiens]
Length = 481
Score = 66.2 bits (160), Expect = 9e-11
Identities = 58/233 (24%), Positives = 98/233 (42%), Gaps = 30/233 (12%)
Query: 6 ASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLL----ASSINGVRC 61
AS ++ +L + + CPIC + E P + CGH CR CL + C
Sbjct: 2 ASAASVTSLADEVNCPICQGTLRE----PVTIDCGHNFCRACLTRYCEIPGPDLEESPTC 57
Query: 62 PFCSKITRITS------LTQLTDNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSC 115
P C + R S L + +N+ L+++ T GL E +C+ G ++ FC
Sbjct: 58 PLCKEPFRPGSFRPNWQLANVVENIERLQLVSTLGLGEED---VCQEHGEKI-YFFCEDD 113
Query: 116 GLVLCEPCREADHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSK 175
+ LC CREA H +++AA R + L LR+ E+Q +
Sbjct: 114 EMQLCVVCREAGEHAT-HTMRFLEDAAAPYREQIHKCLKCLRKEREEIQE-------IQS 165
Query: 176 DLQARYKAVLQEYGHEERRVQDELARSRKFFTGS----LAEVEKSNSQVVEEQ 224
R + +L + + ++V E A RKF LA++E + ++ ++
Sbjct: 166 RENKRMQVLLTQVSTKRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQR 218
>gi|157426896 tripartite motif-containing 10 isoform 2 [Homo
sapiens]
Length = 395
Score = 66.2 bits (160), Expect = 9e-11
Identities = 58/233 (24%), Positives = 98/233 (42%), Gaps = 30/233 (12%)
Query: 6 ASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLL----ASSINGVRC 61
AS ++ +L + + CPIC + E P + CGH CR CL + C
Sbjct: 2 ASAASVTSLADEVNCPICQGTLRE----PVTIDCGHNFCRACLTRYCEIPGPDLEESPTC 57
Query: 62 PFCSKITRITS------LTQLTDNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSC 115
P C + R S L + +N+ L+++ T GL E +C+ G ++ FC
Sbjct: 58 PLCKEPFRPGSFRPNWQLANVVENIERLQLVSTLGLGEED---VCQEHGEKI-YFFCEDD 113
Query: 116 GLVLCEPCREADHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSK 175
+ LC CREA H +++AA R + L LR+ E+Q +
Sbjct: 114 EMQLCVVCREAGEHAT-HTMRFLEDAAAPYREQIHKCLKCLRKEREEIQE-------IQS 165
Query: 176 DLQARYKAVLQEYGHEERRVQDELARSRKFFTGS----LAEVEKSNSQVVEEQ 224
R + +L + + ++V E A RKF LA++E + ++ ++
Sbjct: 166 RENKRMQVLLTQVSTKRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQR 218
>gi|4508005 tripartite motif-containing 26 [Homo sapiens]
Length = 539
Score = 65.5 bits (158), Expect = 2e-10
Identities = 70/277 (25%), Positives = 121/277 (43%), Gaps = 42/277 (15%)
Query: 6 ASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVRCPFCS 65
A+ L +L E + C IC++ + P + CGH CR C + S + CP C
Sbjct: 2 ATSAPLRSLEEEVTCSICLDYLRD----PVTIDCGHVFCRSCTTDVRPISGSRPVCPLCK 57
Query: 66 K------ITRITSLTQLTDNLTVLKIIDTAGLSEAV----GLLMCRSCGRRLPRQFCRSC 115
K I + L L +N+ LK+ E +C +L +C
Sbjct: 58 KPFKKENIRPVWQLASLVENIERLKVDKGRQPGEVTREQQDAKLCERHREKL-HYYCEDD 116
Query: 116 GLVLCEPCREA-DHQPPGHCTLPVKEAAEERRRDFGEKLTRLR----ELMGELQRRKAAL 170
G +LC CRE+ +H+P H + +++AA+ R L+ LR ++ G + +A +
Sbjct: 117 GKLLCVMCRESREHRP--HTAVLMEKAAQPHREKILNHLSTLRRDRDKIQGFQAKGEADI 174
Query: 171 EGVSKDLQARYKAVLQEY--GHE-----ERRVQDELARSRKFFTGSLAEVEKSNSQVVEE 223
K LQ + + ++ E+ GH+ E + ++LA+ + T EK S+ V E
Sbjct: 175 LAALKKLQDQRQYIVAEFEQGHQFLREREEHLLEQLAKLEQELTEGR---EKFKSRGVGE 231
Query: 224 QSYL-LNIAEVQAVSRCDYFLAKIKQADVALLEETAD 259
+ L L I+E++ K +Q L+++T D
Sbjct: 232 LARLALVISELE---------GKAQQPAAELMQDTRD 259
>gi|37622899 ring finger protein 137 [Homo sapiens]
Length = 485
Score = 65.1 bits (157), Expect = 2e-10
Identities = 60/254 (23%), Positives = 116/254 (45%), Gaps = 33/254 (12%)
Query: 11 LDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLL----ASSINGVRCPFCSK 66
++A+ E + CPICM E P + CGH+ C CL L S G CP C
Sbjct: 7 VEAIVEEVACPICMTFLRE----PMSIDCGHSFCHSCLSGLWEIPGESQNWGYTCPLCRA 62
Query: 67 ITRITSLTQLTDNLTVLKIIDTAGLSEAVGLL--MCRSCGRRLPRQFCRSCGLVLCEPCR 124
+ +L V++ + L +GL +C G +L + FC+ L++CE C
Sbjct: 63 PVQPRNLRPNWQLANVVEKVRLLRLHPGMGLKGDLCERHGEKL-KMFCKEDVLIMCEACS 121
Query: 125 EA-DHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGEL------QRRKAALEGVSKDL 177
++ +H+ H +P+++ A E + + E L L++ E +R++ A + +
Sbjct: 122 QSPEHE--AHSVVPMEDVAWEYKWELHEALEHLKKEQEEAWKLEVGERKRTATWKIQVET 179
Query: 178 Q--------ARYKAVLQEYGHEERRVQDELARSRKFFTGSLAE----VEKSNSQVVEEQS 225
+ +Y+ +L++ R++ E+A + AE +E ++S+++++
Sbjct: 180 RKQSIVWEFEKYQRLLEKKQPPHRQLGAEVAAALASLQREAAETMQKLELNHSELIQQSQ 239
Query: 226 YLLN-IAEVQAVSR 238
L IAE++ S+
Sbjct: 240 VLWRMIAELKERSQ 253
>gi|223890259 midline 2 isoform 2 [Homo sapiens]
Length = 705
Score = 63.9 bits (154), Expect = 4e-10
Identities = 69/296 (23%), Positives = 111/296 (37%), Gaps = 61/296 (20%)
Query: 2 AAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASS------ 55
A+ L ++ L L CPIC+E F + P LL C H++C C ++L SS
Sbjct: 12 ASGGLFSLKMETLESELTCPICLELFED----PLLLPCAHSLCFSCAHRILVSSCSSGES 67
Query: 56 ---INGVRCPFCSKITRIT--SLTQLTDNLTVLKIID----------------------- 87
I +CP C + + L L N+T+ IID
Sbjct: 68 IEPITAFQCPTCRYVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYR 127
Query: 88 --TAGLSEAVGLLMCRSCGRRLPRQFCRSCGLVLCEPCREADHQPPGHCTLPVKEAAEER 145
TA SE + C R + C +C + C+ C A H P K+
Sbjct: 128 PTTAMSSERIACQFCEQDPPRDAVKTCITCEVSYCDRCLRATH--------PNKKPFTSH 179
Query: 146 RRDFGEKLTRLRELMG-ELQRRKAALEGVSKD--LQARYKAVLQEYGHEERRVQDELARS 202
R T LR + + + K + VS D + A K V + H+ + D +
Sbjct: 180 RLVEPVPDTHLRGITCLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKL 239
Query: 203 RKFFTGSLAEVEKSNSQVVEEQSYLLNIA----------EVQAVSRCDYFLAKIKQ 248
++ +L + K NS++ + + L+ I E + + CD + I+Q
Sbjct: 240 KQTLEMNLTNLVKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQ 295
>gi|223890257 midline 2 isoform 1 [Homo sapiens]
Length = 735
Score = 63.9 bits (154), Expect = 4e-10
Identities = 69/296 (23%), Positives = 111/296 (37%), Gaps = 61/296 (20%)
Query: 2 AAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASS------ 55
A+ L ++ L L CPIC+E F + P LL C H++C C ++L SS
Sbjct: 12 ASGGLFSLKMETLESELTCPICLELFED----PLLLPCAHSLCFSCAHRILVSSCSSGES 67
Query: 56 ---INGVRCPFCSKITRIT--SLTQLTDNLTVLKIID----------------------- 87
I +CP C + + L L N+T+ IID
Sbjct: 68 IEPITAFQCPTCRYVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYR 127
Query: 88 --TAGLSEAVGLLMCRSCGRRLPRQFCRSCGLVLCEPCREADHQPPGHCTLPVKEAAEER 145
TA SE + C R + C +C + C+ C A H P K+
Sbjct: 128 PTTAMSSERIACQFCEQDPPRDAVKTCITCEVSYCDRCLRATH--------PNKKPFTSH 179
Query: 146 RRDFGEKLTRLRELMG-ELQRRKAALEGVSKD--LQARYKAVLQEYGHEERRVQDELARS 202
R T LR + + + K + VS D + A K V + H+ + D +
Sbjct: 180 RLVEPVPDTHLRGITCLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKL 239
Query: 203 RKFFTGSLAEVEKSNSQVVEEQSYLLNIA----------EVQAVSRCDYFLAKIKQ 248
++ +L + K NS++ + + L+ I E + + CD + I+Q
Sbjct: 240 KQTLEMNLTNLVKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQ 295
>gi|55953112 ret finger protein 2 isoform 2 [Homo sapiens]
Length = 410
Score = 63.9 bits (154), Expect = 4e-10
Identities = 70/278 (25%), Positives = 128/278 (46%), Gaps = 44/278 (15%)
Query: 11 LDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSING-------VRCPF 63
++ L E L CPIC F + P++L C H C++CLE +L S+ +CP
Sbjct: 4 MELLEEDLTCPICCSLFDD----PRVLPCSHNFCKKCLEGILEGSVRNSLWRPAPFKCPT 59
Query: 64 CSKITRITSLTQLTDNLTVLKIIDTAG-LSEAVGLLMCRSCGRRLPRQFCRSCGLVLCEP 122
C K T T + L N ++ I++ + + + +C+ + FC + ++C
Sbjct: 60 CRKETSATGINSLQVNYSLKGIVEKYNKIKISPKMPVCKGHLGQPLNIFCLTDMQLICGI 119
Query: 123 C-READHQPPGHCTLPVKEAAEERRRDF------------GEKLTRLRELMGELQRRKAA 169
C +H C+ +++A + R F G+ L+RL L E +RK +
Sbjct: 120 CATRGEHTKHVFCS--IEDAYAQERDAFESLFQSFETWRRGDALSRLDTL--ETSKRK-S 174
Query: 170 LEGVSKDLQARYKAVLQEYGHEERRVQDELARSRKFFTGSLA-------EVEKSNSQVVE 222
L+ ++KD + K ++ H + ++E+ F T LA E+ K N+ +++
Sbjct: 175 LQLLTKD-SDKVKEFFEKLQHTLDQKKNEILSD--FETMKLAVMQAYDPEINKLNT-ILQ 230
Query: 223 EQSYLLNIAEV-QAVSRCDYFLAKIKQ--ADVALLEET 257
EQ NIAE + VS FL ++++ + +++ET
Sbjct: 231 EQRMAFNIAEAFKDVSEPIVFLQQMQEFREKIKVIKET 268
>gi|47132524 ret finger protein 2 isoform 1 [Homo sapiens]
Length = 407
Score = 63.9 bits (154), Expect = 4e-10
Identities = 70/278 (25%), Positives = 128/278 (46%), Gaps = 44/278 (15%)
Query: 11 LDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSING-------VRCPF 63
++ L E L CPIC F + P++L C H C++CLE +L S+ +CP
Sbjct: 1 MELLEEDLTCPICCSLFDD----PRVLPCSHNFCKKCLEGILEGSVRNSLWRPAPFKCPT 56
Query: 64 CSKITRITSLTQLTDNLTVLKIIDTAG-LSEAVGLLMCRSCGRRLPRQFCRSCGLVLCEP 122
C K T T + L N ++ I++ + + + +C+ + FC + ++C
Sbjct: 57 CRKETSATGINSLQVNYSLKGIVEKYNKIKISPKMPVCKGHLGQPLNIFCLTDMQLICGI 116
Query: 123 C-READHQPPGHCTLPVKEAAEERRRDF------------GEKLTRLRELMGELQRRKAA 169
C +H C+ +++A + R F G+ L+RL L E +RK +
Sbjct: 117 CATRGEHTKHVFCS--IEDAYAQERDAFESLFQSFETWRRGDALSRLDTL--ETSKRK-S 171
Query: 170 LEGVSKDLQARYKAVLQEYGHEERRVQDELARSRKFFTGSLA-------EVEKSNSQVVE 222
L+ ++KD + K ++ H + ++E+ F T LA E+ K N+ +++
Sbjct: 172 LQLLTKD-SDKVKEFFEKLQHTLDQKKNEILSD--FETMKLAVMQAYDPEINKLNT-ILQ 227
Query: 223 EQSYLLNIAEV-QAVSRCDYFLAKIKQ--ADVALLEET 257
EQ NIAE + VS FL ++++ + +++ET
Sbjct: 228 EQRMAFNIAEAFKDVSEPIVFLQQMQEFREKIKVIKET 265
>gi|16445412 ret finger protein 2 isoform 1 [Homo sapiens]
Length = 407
Score = 63.9 bits (154), Expect = 4e-10
Identities = 70/278 (25%), Positives = 128/278 (46%), Gaps = 44/278 (15%)
Query: 11 LDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSING-------VRCPF 63
++ L E L CPIC F + P++L C H C++CLE +L S+ +CP
Sbjct: 1 MELLEEDLTCPICCSLFDD----PRVLPCSHNFCKKCLEGILEGSVRNSLWRPAPFKCPT 56
Query: 64 CSKITRITSLTQLTDNLTVLKIIDTAG-LSEAVGLLMCRSCGRRLPRQFCRSCGLVLCEP 122
C K T T + L N ++ I++ + + + +C+ + FC + ++C
Sbjct: 57 CRKETSATGINSLQVNYSLKGIVEKYNKIKISPKMPVCKGHLGQPLNIFCLTDMQLICGI 116
Query: 123 C-READHQPPGHCTLPVKEAAEERRRDF------------GEKLTRLRELMGELQRRKAA 169
C +H C+ +++A + R F G+ L+RL L E +RK +
Sbjct: 117 CATRGEHTKHVFCS--IEDAYAQERDAFESLFQSFETWRRGDALSRLDTL--ETSKRK-S 171
Query: 170 LEGVSKDLQARYKAVLQEYGHEERRVQDELARSRKFFTGSLA-------EVEKSNSQVVE 222
L+ ++KD + K ++ H + ++E+ F T LA E+ K N+ +++
Sbjct: 172 LQLLTKD-SDKVKEFFEKLQHTLDQKKNEILSD--FETMKLAVMQAYDPEINKLNT-ILQ 227
Query: 223 EQSYLLNIAEV-QAVSRCDYFLAKIKQ--ADVALLEET 257
EQ NIAE + VS FL ++++ + +++ET
Sbjct: 228 EQRMAFNIAEAFKDVSEPIVFLQQMQEFREKIKVIKET 265
>gi|47132521 ret finger protein 2 isoform 1 [Homo sapiens]
Length = 407
Score = 63.9 bits (154), Expect = 4e-10
Identities = 70/278 (25%), Positives = 128/278 (46%), Gaps = 44/278 (15%)
Query: 11 LDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSING-------VRCPF 63
++ L E L CPIC F + P++L C H C++CLE +L S+ +CP
Sbjct: 1 MELLEEDLTCPICCSLFDD----PRVLPCSHNFCKKCLEGILEGSVRNSLWRPAPFKCPT 56
Query: 64 CSKITRITSLTQLTDNLTVLKIIDTAG-LSEAVGLLMCRSCGRRLPRQFCRSCGLVLCEP 122
C K T T + L N ++ I++ + + + +C+ + FC + ++C
Sbjct: 57 CRKETSATGINSLQVNYSLKGIVEKYNKIKISPKMPVCKGHLGQPLNIFCLTDMQLICGI 116
Query: 123 C-READHQPPGHCTLPVKEAAEERRRDF------------GEKLTRLRELMGELQRRKAA 169
C +H C+ +++A + R F G+ L+RL L E +RK +
Sbjct: 117 CATRGEHTKHVFCS--IEDAYAQERDAFESLFQSFETWRRGDALSRLDTL--ETSKRK-S 171
Query: 170 LEGVSKDLQARYKAVLQEYGHEERRVQDELARSRKFFTGSLA-------EVEKSNSQVVE 222
L+ ++KD + K ++ H + ++E+ F T LA E+ K N+ +++
Sbjct: 172 LQLLTKD-SDKVKEFFEKLQHTLDQKKNEILSD--FETMKLAVMQAYDPEINKLNT-ILQ 227
Query: 223 EQSYLLNIAEV-QAVSRCDYFLAKIKQ--ADVALLEET 257
EQ NIAE + VS FL ++++ + +++ET
Sbjct: 228 EQRMAFNIAEAFKDVSEPIVFLQQMQEFREKIKVIKET 265
>gi|5730009 ret finger protein [Homo sapiens]
Length = 513
Score = 63.2 bits (152), Expect = 7e-10
Identities = 44/170 (25%), Positives = 76/170 (44%), Gaps = 10/170 (5%)
Query: 12 DALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVRCPFCSKI---T 68
+ L++ CP+C++ F E P +L CGH IC CL + ++ V CP C +
Sbjct: 8 ECLQQETTCPVCLQYFAE----PMMLDCGHNICCACLARCWGTAETNVSCPQCRETFPQR 63
Query: 69 RITSLTQLTDNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSCGLVLCEPC-READ 127
+ L + ++K + T S G + R + +C + +C C R +
Sbjct: 64 HMRPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICVVCDRSRE 123
Query: 128 HQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDL 177
H+ GH LP++EA E + +L L+ + +RR+A E +L
Sbjct: 124 HR--GHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAEL 171
>gi|62865604 tripartite motif protein 31 [Homo sapiens]
Length = 425
Score = 62.0 bits (149), Expect = 2e-09
Identities = 56/227 (24%), Positives = 100/227 (44%), Gaps = 30/227 (13%)
Query: 6 ASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVRCPFCS 65
AS ++ L+E + CPIC++ +P + CGH C +C+ ++ +S +CP C
Sbjct: 2 ASGQFVNKLQEEVICPICLDILQ----KPVTIDCGHNFCLKCITQIGETSCGFFKCPLCK 57
Query: 66 KITRITSLTQLTDNLTVLKIIDTAGLSEAVGLLMCRSCGR--RLPRQFCRSCGLVLCEPC 123
R ++ + +++ I SE +C R + FC G LC C
Sbjct: 58 TSVRKNAIRFNSLLRNLVEKIQALQASEVQSKRKEATCPRHQEMFHYFCEDDGKFLCFVC 117
Query: 124 REA-DHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDLQARYK 182
RE+ DH+ H ++EAA+ + E++ L++ E + KA +GV R
Sbjct: 118 RESKDHK--SHNVSLIEEAAQNYQGQIQEQIQVLQQKEKETVQVKA--QGVH-----RVD 168
Query: 183 AVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEEQSYLLN 229
+ HE++R+ L E E + + EE+++LL+
Sbjct: 169 VFTDQVEHEKQRI--------------LTEFELLHQVLEEEKNFLLS 201
>gi|169202726 PREDICTED: similar to ring finger protein 18 isoform 1
[Homo sapiens]
Length = 452
Score = 60.8 bits (146), Expect = 4e-09
Identities = 61/215 (28%), Positives = 93/215 (43%), Gaps = 38/215 (17%)
Query: 11 LDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVRCPF---CSKI 67
L + L CPICM F + P + CGH+ CR C +N PF CS+
Sbjct: 6 LQVFQRELICPICMNYFID----PVTIDCGHSFCRPCF------YLNWKDSPFLVQCSEC 55
Query: 68 TRITSLTQLTDNLTVLKIIDTAGLSEAVGLLMCRS-----CG--RRLPRQFCRSCGLVLC 120
T+ T L N+ K+ A L+ V L + S CG R + FC +LC
Sbjct: 56 TKSTGQINLKTNIHFKKM---ASLARKVSLWLFLSSEEQMCGTHRETKKMFCEVDRSLLC 112
Query: 121 EPCREA-DHQPPGHCTLPVKEAAEERRRDFGEKLTRL--------RELMGELQRRKAALE 171
C + +H+ HC P++ AAEE + +K+ L R L E R + +
Sbjct: 113 LLCSSSQEHRDHRHC--PIESAAEEHQEKLLQKMQSLWEKACENHRNLNVETTRTRCWKD 170
Query: 172 GVSKDLQARYKAVLQE---YGHEERRVQDELARSR 203
V+ L+A +A Q+ + HEE + E+ + +
Sbjct: 171 YVNLRLEA-IRAEYQKMPAFHHEEEKHNLEMLKKK 204
>gi|239755488 PREDICTED: similar to ring finger protein 18 isoform 2
[Homo sapiens]
Length = 446
Score = 60.8 bits (146), Expect = 4e-09
Identities = 61/215 (28%), Positives = 93/215 (43%), Gaps = 38/215 (17%)
Query: 11 LDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVRCPF---CSKI 67
L + L CPICM F + P + CGH+ CR C +N PF CS+
Sbjct: 6 LQVFQRELICPICMNYFID----PVTIDCGHSFCRPCF------YLNWKDSPFLVQCSEC 55
Query: 68 TRITSLTQLTDNLTVLKIIDTAGLSEAVGLLMCRS-----CG--RRLPRQFCRSCGLVLC 120
T+ T L N+ K+ A L+ V L + S CG R + FC +LC
Sbjct: 56 TKSTGQINLKTNIHFKKM---ASLARKVSLWLFLSSEEQMCGTHRETKKMFCEVDRSLLC 112
Query: 121 EPCREA-DHQPPGHCTLPVKEAAEERRRDFGEKLTRL--------RELMGELQRRKAALE 171
C + +H+ HC P++ AAEE + +K+ L R L E R + +
Sbjct: 113 LLCSSSQEHRDHRHC--PIESAAEEHQEKLLQKMQSLWEKACENHRNLNVETTRTRCWKD 170
Query: 172 GVSKDLQARYKAVLQE---YGHEERRVQDELARSR 203
V+ L+A +A Q+ + HEE + E+ + +
Sbjct: 171 YVNLRLEA-IRAEYQKMPAFHHEEEKHNLEMLKKK 204
>gi|169203362 PREDICTED: similar to ring finger protein 18 [Homo
sapiens]
Length = 452
Score = 60.8 bits (146), Expect = 4e-09
Identities = 61/215 (28%), Positives = 93/215 (43%), Gaps = 38/215 (17%)
Query: 11 LDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVRCPF---CSKI 67
L + L CPICM F + P + CGH+ CR C +N PF CS+
Sbjct: 6 LQVFQRELICPICMNYFID----PVTIDCGHSFCRPCF------YLNWKDSPFLVQCSEC 55
Query: 68 TRITSLTQLTDNLTVLKIIDTAGLSEAVGLLMCRS-----CG--RRLPRQFCRSCGLVLC 120
T+ T L N+ K+ A L+ V L + S CG R + FC +LC
Sbjct: 56 TKSTGQINLKTNIHFKKM---ASLARKVSLWLFLSSEEQMCGTHRETKKMFCEVDRSLLC 112
Query: 121 EPCREA-DHQPPGHCTLPVKEAAEERRRDFGEKLTRL--------RELMGELQRRKAALE 171
C + +H+ HC P++ AAEE + +K+ L R L E R + +
Sbjct: 113 LLCSSSQEHRDHRHC--PIESAAEEHQEKLLQKMQSLWEKACENHRNLNVETTRTRCWKD 170
Query: 172 GVSKDLQARYKAVLQE---YGHEERRVQDELARSR 203
V+ L+A +A Q+ + HEE + E+ + +
Sbjct: 171 YVNLRLEA-IRAEYQKMPAFHHEEEKHNLEMLKKK 204
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,469,771
Number of Sequences: 37866
Number of extensions: 1195965
Number of successful extensions: 5014
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 91
Number of HSP's successfully gapped in prelim test: 328
Number of HSP's that attempted gapping in prelim test: 4390
Number of HSP's gapped (non-prelim): 701
length of query: 653
length of database: 18,247,518
effective HSP length: 109
effective length of query: 544
effective length of database: 14,120,124
effective search space: 7681347456
effective search space used: 7681347456
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.