Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 153791514

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|153791514 tripartite motif-containing 32 [Homo sapiens]
         (653 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|153791514 tripartite motif-containing 32 [Homo sapiens]           1315   0.0  
gi|153792582 tripartite motif-containing 32 [Homo sapiens]           1315   0.0  
gi|194248081 tripartite motif-containing 2 isoform 2 [Homo sapiens]   117   4e-26
gi|194248079 tripartite motif-containing 2 isoform 1 [Homo sapiens]   117   4e-26
gi|84993742 tripartite motif-containing 71 [Homo sapiens]              74   6e-13
gi|32454739 tripartite motif-containing 3 [Homo sapiens]               72   1e-12
gi|32454737 tripartite motif-containing 3 [Homo sapiens]               72   1e-12
gi|60593056 hypothetical protein LOC283948 [Homo sapiens]              72   1e-12
gi|15208660 tripartite motif protein 21 [Homo sapiens]                 72   2e-12
gi|157743261 tripartite motif-containing 75 [Homo sapiens]             71   4e-12
gi|209862805 SPRY domain containing 5 [Homo sapiens]                   70   8e-12
gi|27436877 tripartite motif-containing 59 [Homo sapiens]              69   2e-11
gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens]     67   4e-11
gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens]     67   4e-11
gi|51477690 tripartite motif-containing 6 and tripartite motif-c...    67   4e-11
gi|157426898 tripartite motif-containing 10 isoform 1 [Homo sapi...    66   9e-11
gi|157426896 tripartite motif-containing 10 isoform 2 [Homo sapi...    66   9e-11
gi|4508005 tripartite motif-containing 26 [Homo sapiens]               65   2e-10
gi|37622899 ring finger protein 137 [Homo sapiens]                     65   2e-10
gi|223890259 midline 2 isoform 2 [Homo sapiens]                        64   4e-10
gi|223890257 midline 2 isoform 1 [Homo sapiens]                        64   4e-10
gi|55953112 ret finger protein 2 isoform 2 [Homo sapiens]              64   4e-10
gi|47132524 ret finger protein 2 isoform 1 [Homo sapiens]              64   4e-10
gi|16445412 ret finger protein 2 isoform 1 [Homo sapiens]              64   4e-10
gi|47132521 ret finger protein 2 isoform 1 [Homo sapiens]              64   4e-10
gi|5730009 ret finger protein [Homo sapiens]                           63   7e-10
gi|62865604 tripartite motif protein 31 [Homo sapiens]                 62   2e-09
gi|169202726 PREDICTED: similar to ring finger protein 18 isofor...    61   4e-09
gi|239755488 PREDICTED: similar to ring finger protein 18 isofor...    61   4e-09
gi|169203362 PREDICTED: similar to ring finger protein 18 [Homo ...    61   4e-09

>gi|153791514 tripartite motif-containing 32 [Homo sapiens]
          Length = 653

 Score = 1315 bits (3404), Expect = 0.0
 Identities = 653/653 (100%), Positives = 653/653 (100%)

Query: 1   MAAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVR 60
           MAAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVR
Sbjct: 1   MAAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVR 60

Query: 61  CPFCSKITRITSLTQLTDNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSCGLVLC 120
           CPFCSKITRITSLTQLTDNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSCGLVLC
Sbjct: 61  CPFCSKITRITSLTQLTDNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSCGLVLC 120

Query: 121 EPCREADHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDLQAR 180
           EPCREADHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDLQAR
Sbjct: 121 EPCREADHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDLQAR 180

Query: 181 YKAVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEEQSYLLNIAEVQAVSRCD 240
           YKAVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEEQSYLLNIAEVQAVSRCD
Sbjct: 181 YKAVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEEQSYLLNIAEVQAVSRCD 240

Query: 241 YFLAKIKQADVALLEETADEEEPELTASLPRELTLQDVELLKVGHVGPLQIGQAVKKPRT 300
           YFLAKIKQADVALLEETADEEEPELTASLPRELTLQDVELLKVGHVGPLQIGQAVKKPRT
Sbjct: 241 YFLAKIKQADVALLEETADEEEPELTASLPRELTLQDVELLKVGHVGPLQIGQAVKKPRT 300

Query: 301 VNVEDSWAMEATASAASTSVTFREMDMSPEEVVASPRASPAKQRGPEAASNIQQCLFLKK 360
           VNVEDSWAMEATASAASTSVTFREMDMSPEEVVASPRASPAKQRGPEAASNIQQCLFLKK
Sbjct: 301 VNVEDSWAMEATASAASTSVTFREMDMSPEEVVASPRASPAKQRGPEAASNIQQCLFLKK 360

Query: 361 MGAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKGFLKEIRRSPSGIDSFVLS 420
           MGAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKGFLKEIRRSPSGIDSFVLS
Sbjct: 361 MGAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKGFLKEIRRSPSGIDSFVLS 420

Query: 421 FLGADLPNLTPLSVAMNCQGLIGVTDSYDNSLKVYTLDGHCVACHRSQLSKPWGITALPS 480
           FLGADLPNLTPLSVAMNCQGLIGVTDSYDNSLKVYTLDGHCVACHRSQLSKPWGITALPS
Sbjct: 421 FLGADLPNLTPLSVAMNCQGLIGVTDSYDNSLKVYTLDGHCVACHRSQLSKPWGITALPS 480

Query: 481 GQFVVTDVEGGKLWCFTVDRGSGVVKYSCLCSAVRPKFVTCDAEGTVYFTQGLGLNLENR 540
           GQFVVTDVEGGKLWCFTVDRGSGVVKYSCLCSAVRPKFVTCDAEGTVYFTQGLGLNLENR
Sbjct: 481 GQFVVTDVEGGKLWCFTVDRGSGVVKYSCLCSAVRPKFVTCDAEGTVYFTQGLGLNLENR 540

Query: 541 QNEHHLEGGFSIGSVGPDGQLGRQISHFFSENEDFRCIAGMCVDARGDLIVADSSRKEIL 600
           QNEHHLEGGFSIGSVGPDGQLGRQISHFFSENEDFRCIAGMCVDARGDLIVADSSRKEIL
Sbjct: 541 QNEHHLEGGFSIGSVGPDGQLGRQISHFFSENEDFRCIAGMCVDARGDLIVADSSRKEIL 600

Query: 601 HFPKGGGYSVLIREGLTCPVGIALTPKGQLLVLDCWDHCIKIYSYHLRRYSTP 653
           HFPKGGGYSVLIREGLTCPVGIALTPKGQLLVLDCWDHCIKIYSYHLRRYSTP
Sbjct: 601 HFPKGGGYSVLIREGLTCPVGIALTPKGQLLVLDCWDHCIKIYSYHLRRYSTP 653


>gi|153792582 tripartite motif-containing 32 [Homo sapiens]
          Length = 653

 Score = 1315 bits (3404), Expect = 0.0
 Identities = 653/653 (100%), Positives = 653/653 (100%)

Query: 1   MAAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVR 60
           MAAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVR
Sbjct: 1   MAAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVR 60

Query: 61  CPFCSKITRITSLTQLTDNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSCGLVLC 120
           CPFCSKITRITSLTQLTDNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSCGLVLC
Sbjct: 61  CPFCSKITRITSLTQLTDNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSCGLVLC 120

Query: 121 EPCREADHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDLQAR 180
           EPCREADHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDLQAR
Sbjct: 121 EPCREADHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDLQAR 180

Query: 181 YKAVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEEQSYLLNIAEVQAVSRCD 240
           YKAVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEEQSYLLNIAEVQAVSRCD
Sbjct: 181 YKAVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEEQSYLLNIAEVQAVSRCD 240

Query: 241 YFLAKIKQADVALLEETADEEEPELTASLPRELTLQDVELLKVGHVGPLQIGQAVKKPRT 300
           YFLAKIKQADVALLEETADEEEPELTASLPRELTLQDVELLKVGHVGPLQIGQAVKKPRT
Sbjct: 241 YFLAKIKQADVALLEETADEEEPELTASLPRELTLQDVELLKVGHVGPLQIGQAVKKPRT 300

Query: 301 VNVEDSWAMEATASAASTSVTFREMDMSPEEVVASPRASPAKQRGPEAASNIQQCLFLKK 360
           VNVEDSWAMEATASAASTSVTFREMDMSPEEVVASPRASPAKQRGPEAASNIQQCLFLKK
Sbjct: 301 VNVEDSWAMEATASAASTSVTFREMDMSPEEVVASPRASPAKQRGPEAASNIQQCLFLKK 360

Query: 361 MGAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKGFLKEIRRSPSGIDSFVLS 420
           MGAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKGFLKEIRRSPSGIDSFVLS
Sbjct: 361 MGAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKGFLKEIRRSPSGIDSFVLS 420

Query: 421 FLGADLPNLTPLSVAMNCQGLIGVTDSYDNSLKVYTLDGHCVACHRSQLSKPWGITALPS 480
           FLGADLPNLTPLSVAMNCQGLIGVTDSYDNSLKVYTLDGHCVACHRSQLSKPWGITALPS
Sbjct: 421 FLGADLPNLTPLSVAMNCQGLIGVTDSYDNSLKVYTLDGHCVACHRSQLSKPWGITALPS 480

Query: 481 GQFVVTDVEGGKLWCFTVDRGSGVVKYSCLCSAVRPKFVTCDAEGTVYFTQGLGLNLENR 540
           GQFVVTDVEGGKLWCFTVDRGSGVVKYSCLCSAVRPKFVTCDAEGTVYFTQGLGLNLENR
Sbjct: 481 GQFVVTDVEGGKLWCFTVDRGSGVVKYSCLCSAVRPKFVTCDAEGTVYFTQGLGLNLENR 540

Query: 541 QNEHHLEGGFSIGSVGPDGQLGRQISHFFSENEDFRCIAGMCVDARGDLIVADSSRKEIL 600
           QNEHHLEGGFSIGSVGPDGQLGRQISHFFSENEDFRCIAGMCVDARGDLIVADSSRKEIL
Sbjct: 541 QNEHHLEGGFSIGSVGPDGQLGRQISHFFSENEDFRCIAGMCVDARGDLIVADSSRKEIL 600

Query: 601 HFPKGGGYSVLIREGLTCPVGIALTPKGQLLVLDCWDHCIKIYSYHLRRYSTP 653
           HFPKGGGYSVLIREGLTCPVGIALTPKGQLLVLDCWDHCIKIYSYHLRRYSTP
Sbjct: 601 HFPKGGGYSVLIREGLTCPVGIALTPKGQLLVLDCWDHCIKIYSYHLRRYSTP 653


>gi|194248081 tripartite motif-containing 2 isoform 2 [Homo sapiens]
          Length = 744

 Score =  117 bits (292), Expect = 4e-26
 Identities = 170/765 (22%), Positives = 291/765 (38%), Gaps = 174/765 (22%)

Query: 15  REVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVRCPFCSK-------- 66
           ++ L C IC+E +      PK+L C HT C +CL+  + +    + CP C +        
Sbjct: 18  KQFLICSICLERYKN----PKVLPCLHTFCERCLQNYIPAHSLTLSCPVCRQTSILPEKG 73

Query: 67  ---------ITRITSLTQLT--DNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSC 115
                    IT +  + Q T   N     I++T     A   L C +    +   +C+SC
Sbjct: 74  VAALQNNFFITNLMDVLQRTPGSNAEESSILETVTAVAAGKPLSCPNHDGNVMEFYCQSC 133

Query: 116 GLVLCEPCREADHQPPGHCTLPVKEAAEERRR--------------DFGEKLTRLRELMG 161
              +C  C E +H    H T+P+K+  E+ +               +    L  + E++ 
Sbjct: 134 ETAMCRECTEGEHAE--HPTVPLKDVVEQHKASLQVQLDAVNKRLPEIDSALQFISEIIH 191

Query: 162 ELQRRKAAL--------EGVSKDLQARYKAVLQE----YGHEERRVQDEL---------A 200
           +L  +KA++        + + K L  R   +L E    YG + + +Q +L          
Sbjct: 192 QLTNQKASIVDDIHSTFDELQKTLNVRKSVLLMELEVNYGLKHKVLQSQLDTLLQGQESI 251

Query: 201 RSRKFFT------GSLAEVEKSNSQVVEEQSYLLN---------------IAEVQAVSRC 239
           +S   FT      G+  EV     Q+ E+ + L +               I E + + + 
Sbjct: 252 KSCSNFTAQALNHGTETEVLLVKKQMSEKLNELADQDFPLHPRENDQLDFIVETEGLKKS 311

Query: 240 DYFLAKIKQADVALLEETADEEEPELTA-SLPRELTL----QDVELLKVGHV-------- 286
            + L  I   +    E  A  E    T    P  +T+    +D EL K G+         
Sbjct: 312 IHNLGTILTTNAVASETVATGEGLRQTIIGQPMSVTITTKDKDGELCKTGNAYLTAELST 371

Query: 287 --GPLQIGQAVKKPR-------TVNVEDSWAM------EATASAASTSVTFREMDMSP-- 329
             G +  G+ +           TV  E  + +      +    +       R  D+SP  
Sbjct: 372 PDGSVADGEILDNKNGTYEFLYTVQKEGDFTLSLRLYDQHIRGSPFKLKVIRSADVSPTT 431

Query: 330 ---EEVVASPRASPAKQR-----------GPEAASNIQQCLFLKKMGAKGSTPGMFNLPV 375
              +  V SP +   KQ+           G    + I+  L  + +G KG   G F    
Sbjct: 432 EGVKRRVKSPGSGHVKQKAVKRPASMYSTGKRKENPIEDDLIFR-VGTKGRNKGEFTNLQ 490

Query: 376 SLYVTSQGEVLVADRGNYRIQVFTRKGFLKE---IR-RSPSGIDSFVLSFLGADLPNLTP 431
            +  ++ G++L+AD  N  +Q+F+  G  K    IR RSP  +                P
Sbjct: 491 GVAASTNGKILIADSNNQCVQIFSNDGQFKSRFGIRGRSPGQLQR--------------P 536

Query: 432 LSVAMNCQGLIGVTDSYDNS-LKVYTLDGHC-VACHRSQLSKPWGITALPSGQFVVTDVE 489
             VA++  G I + D YDN  + +++ DG         +L  P G++   +G  +V D +
Sbjct: 537 TGVAVHPSGDIIIAD-YDNKWVSIFSSDGKFKTKIGSGKLMGPKGVSVDRNGHIIVVDNK 595

Query: 490 GGKLWCFTVDRGSGVVKYSCLCSAVR----PKFVTCDAEGTVYFTQ--GLGLNLENRQNE 543
              ++ F  + G  V ++    +  R    P F   ++   +  T      + + N++ E
Sbjct: 596 ACCVFIFQPN-GKIVTRFGSRGNGDRQFAGPHFAAVNSNNEIIITDFHNHSVKVFNQEGE 654

Query: 544 HHLEGGFSIGSVGPDGQLGRQISHFFSENEDFRCIAGMCVDARGDLIVADSSRKEILHFP 603
             L+        G +G+           N  F    G+ VD+ G++IVAD     I  F 
Sbjct: 655 FMLK-------FGSNGE----------GNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFD 697

Query: 604 KGGGYSVLIR---EGLTCPVGIALTPKGQLLVLDCWDHCIKIYSY 645
             G +   I    + L  P G+ALT  G ++V D  +HC K+Y Y
Sbjct: 698 GSGSFLSYINTSADPLYGPQGLALTSDGHVVVADSGNHCFKVYRY 742


>gi|194248079 tripartite motif-containing 2 isoform 1 [Homo sapiens]
          Length = 771

 Score =  117 bits (292), Expect = 4e-26
 Identities = 170/765 (22%), Positives = 291/765 (38%), Gaps = 174/765 (22%)

Query: 15  REVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVRCPFCSK-------- 66
           ++ L C IC+E +      PK+L C HT C +CL+  + +    + CP C +        
Sbjct: 45  KQFLICSICLERYKN----PKVLPCLHTFCERCLQNYIPAHSLTLSCPVCRQTSILPEKG 100

Query: 67  ---------ITRITSLTQLT--DNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSC 115
                    IT +  + Q T   N     I++T     A   L C +    +   +C+SC
Sbjct: 101 VAALQNNFFITNLMDVLQRTPGSNAEESSILETVTAVAAGKPLSCPNHDGNVMEFYCQSC 160

Query: 116 GLVLCEPCREADHQPPGHCTLPVKEAAEERRR--------------DFGEKLTRLRELMG 161
              +C  C E +H    H T+P+K+  E+ +               +    L  + E++ 
Sbjct: 161 ETAMCRECTEGEHAE--HPTVPLKDVVEQHKASLQVQLDAVNKRLPEIDSALQFISEIIH 218

Query: 162 ELQRRKAAL--------EGVSKDLQARYKAVLQE----YGHEERRVQDEL---------A 200
           +L  +KA++        + + K L  R   +L E    YG + + +Q +L          
Sbjct: 219 QLTNQKASIVDDIHSTFDELQKTLNVRKSVLLMELEVNYGLKHKVLQSQLDTLLQGQESI 278

Query: 201 RSRKFFT------GSLAEVEKSNSQVVEEQSYLLN---------------IAEVQAVSRC 239
           +S   FT      G+  EV     Q+ E+ + L +               I E + + + 
Sbjct: 279 KSCSNFTAQALNHGTETEVLLVKKQMSEKLNELADQDFPLHPRENDQLDFIVETEGLKKS 338

Query: 240 DYFLAKIKQADVALLEETADEEEPELTA-SLPRELTL----QDVELLKVGHV-------- 286
            + L  I   +    E  A  E    T    P  +T+    +D EL K G+         
Sbjct: 339 IHNLGTILTTNAVASETVATGEGLRQTIIGQPMSVTITTKDKDGELCKTGNAYLTAELST 398

Query: 287 --GPLQIGQAVKKPR-------TVNVEDSWAM------EATASAASTSVTFREMDMSP-- 329
             G +  G+ +           TV  E  + +      +    +       R  D+SP  
Sbjct: 399 PDGSVADGEILDNKNGTYEFLYTVQKEGDFTLSLRLYDQHIRGSPFKLKVIRSADVSPTT 458

Query: 330 ---EEVVASPRASPAKQR-----------GPEAASNIQQCLFLKKMGAKGSTPGMFNLPV 375
              +  V SP +   KQ+           G    + I+  L  + +G KG   G F    
Sbjct: 459 EGVKRRVKSPGSGHVKQKAVKRPASMYSTGKRKENPIEDDLIFR-VGTKGRNKGEFTNLQ 517

Query: 376 SLYVTSQGEVLVADRGNYRIQVFTRKGFLKE---IR-RSPSGIDSFVLSFLGADLPNLTP 431
            +  ++ G++L+AD  N  +Q+F+  G  K    IR RSP  +                P
Sbjct: 518 GVAASTNGKILIADSNNQCVQIFSNDGQFKSRFGIRGRSPGQLQR--------------P 563

Query: 432 LSVAMNCQGLIGVTDSYDNS-LKVYTLDGHC-VACHRSQLSKPWGITALPSGQFVVTDVE 489
             VA++  G I + D YDN  + +++ DG         +L  P G++   +G  +V D +
Sbjct: 564 TGVAVHPSGDIIIAD-YDNKWVSIFSSDGKFKTKIGSGKLMGPKGVSVDRNGHIIVVDNK 622

Query: 490 GGKLWCFTVDRGSGVVKYSCLCSAVR----PKFVTCDAEGTVYFTQ--GLGLNLENRQNE 543
              ++ F  + G  V ++    +  R    P F   ++   +  T      + + N++ E
Sbjct: 623 ACCVFIFQPN-GKIVTRFGSRGNGDRQFAGPHFAAVNSNNEIIITDFHNHSVKVFNQEGE 681

Query: 544 HHLEGGFSIGSVGPDGQLGRQISHFFSENEDFRCIAGMCVDARGDLIVADSSRKEILHFP 603
             L+        G +G+           N  F    G+ VD+ G++IVAD     I  F 
Sbjct: 682 FMLK-------FGSNGE----------GNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFD 724

Query: 604 KGGGYSVLIR---EGLTCPVGIALTPKGQLLVLDCWDHCIKIYSY 645
             G +   I    + L  P G+ALT  G ++V D  +HC K+Y Y
Sbjct: 725 GSGSFLSYINTSADPLYGPQGLALTSDGHVVVADSGNHCFKVYRY 769


>gi|84993742 tripartite motif-containing 71 [Homo sapiens]
          Length = 868

 Score = 73.6 bits (179), Expect = 6e-13
 Identities = 77/301 (25%), Positives = 123/301 (40%), Gaps = 48/301 (15%)

Query: 362 GAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKGFLKEIRRSPSGIDSFVLSF 421
           G++G + G    P  + V  +G ++VADR N RIQVF            P G        
Sbjct: 597 GSEGDSDGKLCRPWGVSVDKEGYIIVADRSNNRIQVF-----------KPCGAFHHKFGT 645

Query: 422 LGADLPNL-TPLSVAMNCQGLIGVTDSYDNSLKVYTLDGHCV------ACHRSQLSKPWG 474
           LG+       P  VA +    I V D  ++ ++++T +G  +           Q + PW 
Sbjct: 646 LGSRPGQFDRPAGVACDASRRIVVADKDNHRIQIFTFEGQFLLKFGEKGTKNGQFNYPWD 705

Query: 475 ITALPSGQFVVTDVEGGKLWCFTVDRGSGVVKYSCLCSAVR----PKFVTCDAEGTVYFT 530
           +     G+ +V+D    ++  F  D G  + KY    +  +    P+ V  + EG +  T
Sbjct: 706 VAVNSEGKILVSDTRNHRIQLFGPD-GVFLNKYGFEGALWKHFDSPRGVAFNHEGHLVVT 764

Query: 531 QGLGLNLENRQNEHHLEGGFSIGSVGPDGQLGRQISHFFSENEDFRCIAGMCVDARGDLI 590
                      N H L        + PD Q  R +    + N  F    G+ VD  G +I
Sbjct: 765 D---------FNNHRLL------VIHPDCQSARFLGSEGTGNGQFLRPQGVAVDQEGRII 809

Query: 591 VADSSRKEILHFPKGGGYSVLIREG--------LTCPVGIALTPKGQLLVLDCWDHCIKI 642
           VADS    +  F   G  S L + G        +  P GIA+TP G ++V+D  ++ I +
Sbjct: 810 VADSRNHRVQMFESNG--SFLCKFGAQGSGFGQMDRPSGIAITPDGMIVVVDFGNNRILV 867

Query: 643 Y 643
           +
Sbjct: 868 F 868



 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 51/182 (28%), Positives = 77/182 (42%), Gaps = 23/182 (12%)

Query: 357 FLKKMGAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKGFLKEIRRSPSGIDS 416
           FL K G KG+  G FN P  + V S+G++LV+D  N+RIQ+F            P G+  
Sbjct: 686 FLLKFGEKGTKNGQFNYPWDVAVNSEGKILVSDTRNHRIQLF-----------GPDGVFL 734

Query: 417 FVLSFLGADLPNL-TPLSVAMNCQGLIGVTDSYDNSLKVYTLDGHCV------ACHRSQL 469
               F GA   +  +P  VA N +G + VTD  ++ L V   D               Q 
Sbjct: 735 NKYGFEGALWKHFDSPRGVAFNHEGHLVVTDFNNHRLLVIHPDCQSARFLGSEGTGNGQF 794

Query: 470 SKPWGITALPSGQFVVTDVEGGKLWCFTVDRGSGVVKYSCLCSAV----RPKFVTCDAEG 525
            +P G+     G+ +V D    ++  F    GS + K+    S      RP  +    +G
Sbjct: 795 LRPQGVAVDQEGRIIVADSRNHRVQMFE-SNGSFLCKFGAQGSGFGQMDRPSGIAITPDG 853

Query: 526 TV 527
            +
Sbjct: 854 MI 855



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 37/151 (24%), Positives = 65/151 (43%), Gaps = 24/151 (15%)

Query: 356 LFLKKMGAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKGFLKEIRRSPSGID 415
           +FL K G +G+    F+ P  +    +G ++V D  N+R+ V                 D
Sbjct: 732 VFLNKYGFEGALWKHFDSPRGVAFNHEGHLVVTDFNNHRLLVIHP--------------D 777

Query: 416 SFVLSFLGADLPN----LTPLSVAMNCQGLIGVTDSYDNSLKVYTLDGHCVACHRS---- 467
                FLG++       L P  VA++ +G I V DS ++ ++++  +G  +    +    
Sbjct: 778 CQSARFLGSEGTGNGQFLRPQGVAVDQEGRIIVADSRNHRVQMFESNGSFLCKFGAQGSG 837

Query: 468 --QLSKPWGITALPSGQFVVTDVEGGKLWCF 496
             Q+ +P GI   P G  VV D    ++  F
Sbjct: 838 FGQMDRPSGIAITPDGMIVVVDFGNNRILVF 868



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 28/102 (27%), Positives = 47/102 (46%), Gaps = 12/102 (11%)

Query: 355 CLFLKKMGAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKG-FLKEIRRSPSG 413
           C   + +G++G+  G F  P  + V  +G ++VAD  N+R+Q+F   G FL +     SG
Sbjct: 778 CQSARFLGSEGTGNGQFLRPQGVAVDQEGRIIVADSRNHRVQMFESNGSFLCKFGAQGSG 837

Query: 414 IDSFVLSFLGADLPNLTPLSVAMNCQGLIGVTDSYDNSLKVY 455
                            P  +A+   G+I V D  +N + V+
Sbjct: 838 FGQMD-----------RPSGIAITPDGMIVVVDFGNNRILVF 868


>gi|32454739 tripartite motif-containing 3 [Homo sapiens]
          Length = 744

 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 78/299 (26%), Positives = 123/299 (41%), Gaps = 44/299 (14%)

Query: 360 KMGAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKGFLK---EIR-RSPSGID 415
           ++G++G   G F     +   S G ++VAD  N  IQVF+ +G  K    +R RSP  + 
Sbjct: 475 RVGSRGREKGEFTNLQGVSAASSGRIVVADSNNQCIQVFSNEGQFKFRFGVRGRSPGQLQ 534

Query: 416 SFVLSFLGADLPNLTPLSVAMNCQGLIGVTDSYDNS-LKVYTLDGHC-VACHRSQLSKPW 473
                          P  VA++  G I V D YDN  + +++ +G         +L  P 
Sbjct: 535 R--------------PTGVAVDTNGDIIVAD-YDNRWVSIFSPEGKFKTKIGAGRLMGPK 579

Query: 474 GITALPSGQFVVTDVEGGKLWCFTVDRGSGVVKYSCLCSAVR----PKFVTCDAEGTVYF 529
           G+    +G  +V D +   ++ F  + G  V ++    +  R    P FV  + +  +  
Sbjct: 580 GVAVDRNGHIIVVDNKSCCVFTFQPN-GKLVGRFGGRGATDRHFAGPHFVAVNNKNEIVV 638

Query: 530 TQGLGLNLENRQNEHHLEGGFSIGSVGPDGQLGRQISHFFSENEDFRCIAGMCVDARGDL 589
           T            + H     S+     DG+   +       N  F    G+ VD+ G++
Sbjct: 639 T------------DFH---NHSVKVYSADGEFLFKFGSHGEGNGQFNAPTGVAVDSNGNI 683

Query: 590 IVADSSRKEILHFPKGGGYSVLIR---EGLTCPVGIALTPKGQLLVLDCWDHCIKIYSY 645
           IVAD     I  F   G +   I    E L  P G+ALT  G ++V D  +HC K Y Y
Sbjct: 684 IVADWGNSRIQVFDSSGSFLSYINTSAEPLYGPQGLALTSDGHVVVADAGNHCFKAYRY 742



 Score = 70.1 bits (170), Expect = 6e-12
 Identities = 74/344 (21%), Positives = 135/344 (39%), Gaps = 41/344 (11%)

Query: 15  REVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVRCPFC--SKITRITS 72
           ++ L C IC++ +      PK+L C HT C +CL+  + +    + CP C  + I     
Sbjct: 17  KQFLVCSICLDRYQ----CPKVLPCLHTFCERCLQNYIPAQSLTLSCPVCRQTSILPEQG 72

Query: 73  LTQLTDNLTVLKII--------------DTAGLSEAVGL-LMCRSCGRRLPRQFCRSCGL 117
           ++ L +N  +  ++              D   LS   G  L C +   +    +C +C  
Sbjct: 73  VSALQNNFFISSLMEAMQQAPDGAHDPEDPHPLSVVAGRPLSCPNHEGKTMEFYCEACET 132

Query: 118 VLCEPCREADHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDL 177
            +C  CR  +H+   H T+ +++  E+ +     +L  +R  + +L    A + G+S+ L
Sbjct: 133 AMCGECRAGEHRE--HGTVLLRDVVEQHKAALQRQLEAVRGRLPQLSAAIALVGGISQQL 190

Query: 178 QARYKAVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEEQSYLLNIAEVQAVS 237
           Q R    L +       ++  L + ++     L  +  +  +V++ Q   L   +    S
Sbjct: 191 QERKAEALAQISAAFEDLEQALQQRKQALVSDLETICGAKQKVLQSQLDTLRQGQEHIGS 250

Query: 238 RCDY--------------FLAKIKQADVALLEETADEEEPELTASLPRELTLQ-DVELLK 282
            C +               + K  +  +A L   A  E P   A L  EL L+ D     
Sbjct: 251 SCSFAEQALRLGSAPEVLLVRKHMRERLAALAAQAFPERPHENAQL--ELVLEVDGLRRS 308

Query: 283 VGHVGPLQIGQAVKKPRTVNVEDSWAMEATASAASTSVTFREMD 326
           V ++G L    A     TV   +          AS +VT ++ D
Sbjct: 309 VLNLGALLTTSATAH-ETVATGEGLRQALVGQPASLTVTTKDKD 351



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 35/100 (35%), Positives = 45/100 (45%), Gaps = 15/100 (15%)

Query: 357 FLKKMGAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKG-FLKEIRRSPSGID 415
           FL K G+ G   G FN P  + V S G ++VAD GN RIQVF   G FL  I  S     
Sbjct: 655 FLFKFGSHGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDSSGSFLSYINTSAE--- 711

Query: 416 SFVLSFLGADLPNLTPLSVAMNCQGLIGVTDSYDNSLKVY 455
                      P   P  +A+   G + V D+ ++  K Y
Sbjct: 712 -----------PLYGPQGLALTSDGHVVVADAGNHCFKAY 740



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 42/178 (23%), Positives = 70/178 (39%), Gaps = 38/178 (21%)

Query: 357 FLKKMGAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKGFLKE-----IRRSP 411
           F  + G +G +PG    P  + V + G+++VAD  N  + +F+ +G  K          P
Sbjct: 519 FKFRFGVRGRSPGQLQRPTGVAVDTNGDIIVADYDNRWVSIFSPEGKFKTKIGAGRLMGP 578

Query: 412 SGI--------------DSFVLSFL-------------GADLPNLTPLSVAMNCQGLIGV 444
            G+                 V +F                D     P  VA+N +  I V
Sbjct: 579 KGVAVDRNGHIIVVDNKSCCVFTFQPNGKLVGRFGGRGATDRHFAGPHFVAVNNKNEIVV 638

Query: 445 TDSYDNSLKVYTLDGHCV---ACH---RSQLSKPWGITALPSGQFVVTDVEGGKLWCF 496
           TD +++S+KVY+ DG  +     H     Q + P G+    +G  +V D    ++  F
Sbjct: 639 TDFHNHSVKVYSADGEFLFKFGSHGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVF 696


>gi|32454737 tripartite motif-containing 3 [Homo sapiens]
          Length = 744

 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 78/299 (26%), Positives = 123/299 (41%), Gaps = 44/299 (14%)

Query: 360 KMGAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKGFLK---EIR-RSPSGID 415
           ++G++G   G F     +   S G ++VAD  N  IQVF+ +G  K    +R RSP  + 
Sbjct: 475 RVGSRGREKGEFTNLQGVSAASSGRIVVADSNNQCIQVFSNEGQFKFRFGVRGRSPGQLQ 534

Query: 416 SFVLSFLGADLPNLTPLSVAMNCQGLIGVTDSYDNS-LKVYTLDGHC-VACHRSQLSKPW 473
                          P  VA++  G I V D YDN  + +++ +G         +L  P 
Sbjct: 535 R--------------PTGVAVDTNGDIIVAD-YDNRWVSIFSPEGKFKTKIGAGRLMGPK 579

Query: 474 GITALPSGQFVVTDVEGGKLWCFTVDRGSGVVKYSCLCSAVR----PKFVTCDAEGTVYF 529
           G+    +G  +V D +   ++ F  + G  V ++    +  R    P FV  + +  +  
Sbjct: 580 GVAVDRNGHIIVVDNKSCCVFTFQPN-GKLVGRFGGRGATDRHFAGPHFVAVNNKNEIVV 638

Query: 530 TQGLGLNLENRQNEHHLEGGFSIGSVGPDGQLGRQISHFFSENEDFRCIAGMCVDARGDL 589
           T            + H     S+     DG+   +       N  F    G+ VD+ G++
Sbjct: 639 T------------DFH---NHSVKVYSADGEFLFKFGSHGEGNGQFNAPTGVAVDSNGNI 683

Query: 590 IVADSSRKEILHFPKGGGYSVLIR---EGLTCPVGIALTPKGQLLVLDCWDHCIKIYSY 645
           IVAD     I  F   G +   I    E L  P G+ALT  G ++V D  +HC K Y Y
Sbjct: 684 IVADWGNSRIQVFDSSGSFLSYINTSAEPLYGPQGLALTSDGHVVVADAGNHCFKAYRY 742



 Score = 70.1 bits (170), Expect = 6e-12
 Identities = 74/344 (21%), Positives = 135/344 (39%), Gaps = 41/344 (11%)

Query: 15  REVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVRCPFC--SKITRITS 72
           ++ L C IC++ +      PK+L C HT C +CL+  + +    + CP C  + I     
Sbjct: 17  KQFLVCSICLDRYQ----CPKVLPCLHTFCERCLQNYIPAQSLTLSCPVCRQTSILPEQG 72

Query: 73  LTQLTDNLTVLKII--------------DTAGLSEAVGL-LMCRSCGRRLPRQFCRSCGL 117
           ++ L +N  +  ++              D   LS   G  L C +   +    +C +C  
Sbjct: 73  VSALQNNFFISSLMEAMQQAPDGAHDPEDPHPLSVVAGRPLSCPNHEGKTMEFYCEACET 132

Query: 118 VLCEPCREADHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDL 177
            +C  CR  +H+   H T+ +++  E+ +     +L  +R  + +L    A + G+S+ L
Sbjct: 133 AMCGECRAGEHRE--HGTVLLRDVVEQHKAALQRQLEAVRGRLPQLSAAIALVGGISQQL 190

Query: 178 QARYKAVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEEQSYLLNIAEVQAVS 237
           Q R    L +       ++  L + ++     L  +  +  +V++ Q   L   +    S
Sbjct: 191 QERKAEALAQISAAFEDLEQALQQRKQALVSDLETICGAKQKVLQSQLDTLRQGQEHIGS 250

Query: 238 RCDY--------------FLAKIKQADVALLEETADEEEPELTASLPRELTLQ-DVELLK 282
            C +               + K  +  +A L   A  E P   A L  EL L+ D     
Sbjct: 251 SCSFAEQALRLGSAPEVLLVRKHMRERLAALAAQAFPERPHENAQL--ELVLEVDGLRRS 308

Query: 283 VGHVGPLQIGQAVKKPRTVNVEDSWAMEATASAASTSVTFREMD 326
           V ++G L    A     TV   +          AS +VT ++ D
Sbjct: 309 VLNLGALLTTSATAH-ETVATGEGLRQALVGQPASLTVTTKDKD 351



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 35/100 (35%), Positives = 45/100 (45%), Gaps = 15/100 (15%)

Query: 357 FLKKMGAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKG-FLKEIRRSPSGID 415
           FL K G+ G   G FN P  + V S G ++VAD GN RIQVF   G FL  I  S     
Sbjct: 655 FLFKFGSHGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDSSGSFLSYINTSAE--- 711

Query: 416 SFVLSFLGADLPNLTPLSVAMNCQGLIGVTDSYDNSLKVY 455
                      P   P  +A+   G + V D+ ++  K Y
Sbjct: 712 -----------PLYGPQGLALTSDGHVVVADAGNHCFKAY 740



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 42/178 (23%), Positives = 70/178 (39%), Gaps = 38/178 (21%)

Query: 357 FLKKMGAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKGFLKE-----IRRSP 411
           F  + G +G +PG    P  + V + G+++VAD  N  + +F+ +G  K          P
Sbjct: 519 FKFRFGVRGRSPGQLQRPTGVAVDTNGDIIVADYDNRWVSIFSPEGKFKTKIGAGRLMGP 578

Query: 412 SGI--------------DSFVLSFL-------------GADLPNLTPLSVAMNCQGLIGV 444
            G+                 V +F                D     P  VA+N +  I V
Sbjct: 579 KGVAVDRNGHIIVVDNKSCCVFTFQPNGKLVGRFGGRGATDRHFAGPHFVAVNNKNEIVV 638

Query: 445 TDSYDNSLKVYTLDGHCV---ACH---RSQLSKPWGITALPSGQFVVTDVEGGKLWCF 496
           TD +++S+KVY+ DG  +     H     Q + P G+    +G  +V D    ++  F
Sbjct: 639 TDFHNHSVKVYSADGEFLFKFGSHGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVF 696


>gi|60593056 hypothetical protein LOC283948 [Homo sapiens]
          Length = 123

 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 37/87 (42%), Positives = 52/87 (59%), Gaps = 6/87 (6%)

Query: 557 PDGQLGRQISHFFSENEDFRCIAGMCVDARGDLIVADSSRKEILHFPKGGGYSVLIREGL 616
           P G LG    H F       C AG+C ++ G++IVAD  R+++  FP+ G    L+ EGL
Sbjct: 36  PLGSLGGWTGHTFG------CPAGICSNSEGNVIVADEQRRQVTLFPRAGPPICLVSEGL 89

Query: 617 TCPVGIALTPKGQLLVLDCWDHCIKIY 643
             P+G+A  P+GQLLV D  D+ IK+Y
Sbjct: 90  GQPLGVACAPQGQLLVADAKDNSIKVY 116



 Score = 37.7 bits (86), Expect = 0.034
 Identities = 30/91 (32%), Positives = 40/91 (43%), Gaps = 16/91 (17%)

Query: 365 GSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKGFLKEIRRSPSGIDSFVLSFLGA 424
           G T   F  P  +   S+G V+VAD    ++ +F R G        P  + S  L     
Sbjct: 42  GWTGHTFGCPAGICSNSEGNVIVADEQRRQVTLFPRAG-------PPICLVSEGLG---- 90

Query: 425 DLPNLTPLSVAMNCQGLIGVTDSYDNSLKVY 455
                 PL VA   QG + V D+ DNS+KVY
Sbjct: 91  -----QPLGVACAPQGQLLVADAKDNSIKVY 116



 Score = 31.2 bits (69), Expect = 3.1
 Identities = 14/63 (22%), Positives = 26/63 (41%)

Query: 431 PLSVAMNCQGLIGVTDSYDNSLKVYTLDGHCVACHRSQLSKPWGITALPSGQFVVTDVEG 490
           P  +  N +G + V D     + ++   G  +      L +P G+   P GQ +V D + 
Sbjct: 51  PAGICSNSEGNVIVADEQRRQVTLFPRAGPPICLVSEGLGQPLGVACAPQGQLLVADAKD 110

Query: 491 GKL 493
             +
Sbjct: 111 NSI 113


>gi|15208660 tripartite motif protein 21 [Homo sapiens]
          Length = 475

 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 75/299 (25%), Positives = 129/299 (43%), Gaps = 35/299 (11%)

Query: 6   ASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVRCPFCS 65
           AS   L  + E + CPIC++ F E    P  + CGH+ C++C+ ++      G  CP C 
Sbjct: 2   ASAARLTMMWEEVTCPICLDPFVE----PVSIECGHSFCQECISQV--GKGGGSVCPVCR 55

Query: 66  KITRITSL---TQLTDNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSCGLVLCEP 122
           +   + +L    QL + +  LK I         G   C   G RL   FC   G  LC  
Sbjct: 56  QRFLLKNLRPNRQLANMVNNLKEISQEAREGTQG-ERCAVHGERL-HLFCEKDGKALCWV 113

Query: 123 CREADHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDLQARYK 182
           C ++  +   H  +P++EAA+E +        +L+  +GEL+R++   E +  ++  +  
Sbjct: 114 CAQS-RKHRDHAMVPLEEAAQEYQE-------KLQVALGELRRKQELAEKLEVEIAIKRA 165

Query: 183 AVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVE----EQSYLLNIAEVQAVSR 238
              +    ++ R+  E  + + F    L E E+   Q +E    EQ  +L   E +   +
Sbjct: 166 DWKKTVETQKSRIHAEFVQQKNF----LVEEEQRQLQELEKDEREQLRILGEKEAKLAQQ 221

Query: 239 CDYFLAKIKQAD-------VALLEETADEEEPELTASLPRELTLQDVELLKVGHVGPLQ 290
                  I + D       + LL+E     E   + +L ++L +   EL  V HV  L+
Sbjct: 222 SQALQELISELDRRCHSSALELLQEVIIVLERSESWNL-KDLDITSPELRSVCHVPGLK 279


>gi|157743261 tripartite motif-containing 75 [Homo sapiens]
          Length = 468

 Score = 70.9 bits (172), Expect = 4e-12
 Identities = 69/283 (24%), Positives = 121/283 (42%), Gaps = 35/283 (12%)

Query: 1   MAAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVR 60
           MA AAA    L  L+   +C IC++  ++    P  + CGH  CR C+++          
Sbjct: 1   MAVAAA----LTGLQAEAKCSICLDYLSD----PVTIECGHNFCRSCIQQSWLDLQELFP 52

Query: 61  CPFCSKITR---ITSLTQLTDNLTVLKIIDT--AGLSEAVGLLMCRSCGRRLPRQFCRSC 115
           CP C    +     S TQL   + + K++ +  +   +     +C    + L   FC+  
Sbjct: 53  CPVCRHQCQEGHFRSNTQLGRMIEIAKLLQSTKSNKRKQEETTLCEKHNQPLS-VFCKED 111

Query: 116 GLVLCEPCREA-DHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVS 174
            +VLC  C +  DHQ  GH   P+++AA   R+ F   +  L++ + +LQ+  +      
Sbjct: 112 LMVLCPLCTQPPDHQ--GHHVRPIEKAAIHYRKRFCSYIQPLKKQLADLQKLISTQSKKP 169

Query: 175 KDLQARYKAVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEE----------- 223
            +L+   +   QE   E   +   L R ++     LAE EK N Q +             
Sbjct: 170 LELREMVENQRQELSSEFEHLNQFLDREQQAVLSRLAEEEKDNQQKLSANITAFSNYSAT 229

Query: 224 -QSYLLNIAEVQAVSRCDYFLAKIKQADVALLEETADEEEPEL 265
            +S L  + E+  +S  +  L++IK     +  E+ +E  P +
Sbjct: 230 LKSQLSKVVELSELSELE-LLSQIK-----IFYESENESSPSI 266


>gi|209862805 SPRY domain containing 5 [Homo sapiens]
          Length = 452

 Score = 69.7 bits (169), Expect = 8e-12
 Identities = 77/282 (27%), Positives = 121/282 (42%), Gaps = 40/282 (14%)

Query: 11  LDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVRCPFCSKITRI 70
           L   +  L CPICM  F    L P  + CGH+ CR CL      +    +C  C K TR 
Sbjct: 6   LQVFQRALTCPICMNYF----LDPVTIDCGHSFCRPCLYLNWQDTAVLAQCSECKKTTRQ 61

Query: 71  TSLTQLTDNLTVLKIIDTAGLSEAVGLLMCRS-----CG--RRLPRQFCRSCGLVLCEPC 123
            +L       T + + + A ++    L    S     CG  R   + FC     +LC PC
Sbjct: 62  RNLN------TDICLKNMAFIARKASLRQFLSSEEQICGMHRETKKMFCEVDKSLLCLPC 115

Query: 124 REA-DHQPPGHCTLPVKEAAEERRRDFGEKL--------TRLRELMGELQRRKAALEGVS 174
             + +H+   HC  P++ AAEERR +  +K+          LR L  E  R +   + VS
Sbjct: 116 SNSQEHRNHIHC--PIEWAAEERREELLKKMQSLWEKACENLRNLNMETTRTRCWKDYVS 173

Query: 175 ---KDLQARYKAVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEEQSYLLNIA 231
              + ++A Y+  +  + HEE   Q  L R RK       ++ +S +++   +  L  + 
Sbjct: 174 LRIEAIRAEYQK-MPAFLHEEE--QHHLERLRKEGEDIFQQLNESKARMEHSRELLRGMY 230

Query: 232 E--VQAVSRCDYFLAK----IKQADVALLEETADEEEPELTA 267
           E   Q   + D  L +    I     +LL + ++   PEL+A
Sbjct: 231 EDLKQMCHKADVELLQAFGDILHRYESLLLQVSEPVNPELSA 272


>gi|27436877 tripartite motif-containing 59 [Homo sapiens]
          Length = 403

 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 86/344 (25%), Positives = 147/344 (42%), Gaps = 58/344 (16%)

Query: 16  EVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSIN---------GVRCPFCSK 66
           E L CPIC   F +    P++L C HT CR CLE +L +S N          ++CP C  
Sbjct: 6   EELTCPICYSIFED----PRVLPCSHTFCRNCLENILQASGNFYIWRPLRIPLKCPNCRS 61

Query: 67  ITRI--TSLTQLTDNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSCGLVLCEPCR 124
           IT I  T +  L  N  +  II+     +   ++ C    R+    +C     ++C  C 
Sbjct: 62  ITEIAPTGIESLPVNFALRAIIEKYQQEDHPDIVTCPEHYRQPLNVYCLLDKKLVCGHCL 121

Query: 125 EADHQPPGHCTLPVKEAAEERRRDFGEKL---------TRLRELMGELQRRKAALEGVSK 175
               Q  GH  +   ++A  + +D  +KL         T L  L+ +L+ +K+  E   K
Sbjct: 122 TIG-QHHGH-PIDDLQSAYLKEKDTPQKLLEQLTDTHWTDLTHLIEKLKEQKSHSE---K 176

Query: 176 DLQARYKAVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEEQSYLLNIAEVQA 235
            +Q   +AVLQ +    + + D L + +K F  +L +V             L+N      
Sbjct: 177 MIQGDKEAVLQYF----KELNDTLEQKKKSFLTALCDV-----------GNLINQEYTPQ 221

Query: 236 VSRCDYFLAKIKQADVALLEETAD-EEEPELTASLPRELTLQDVELLK---VGHVGPLQI 291
           + R    + +I++  + L+  T   +EE  L      +   Q V++LK   +  V P++I
Sbjct: 222 IER----MKEIREQQLELMALTISLQEESPLKFLEKVDDVRQHVQILKQRPLPEVQPVEI 277

Query: 292 GQAVKKPRTVNVEDSWAMEATASAASTSVTFREMDMSPEEVVAS 335
              V K     +++ W+   T      +V   +M +SP+ +  S
Sbjct: 278 YPRVSK----ILKEEWS--RTEIGQIKNVLIPKMKISPKRMSCS 315


>gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens]
          Length = 488

 Score = 67.4 bits (163), Expect = 4e-11
 Identities = 53/216 (24%), Positives = 96/216 (44%), Gaps = 12/216 (5%)

Query: 14  LREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVR----CPFCSKITR 69
           +RE + CPIC+E  TE    P  + CGH+ C+ C+      S+ G      CP C    +
Sbjct: 9   IREEVTCPICLELLTE----PLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQ 64

Query: 70  ITSLTQLTDNLTVLKIIDTA--GLSEAVGLLMCRSCGRRLPRQFCRSCGLVLCEPCREAD 127
             +L        +++ +     G  + +  ++C   G +L + FC+  G V+C  C E  
Sbjct: 65  PGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKL-QLFCQEDGKVICWLC-ERS 122

Query: 128 HQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDLQARYKAVLQE 187
            +  GH T  V+E A+E +  F E L +L+    E ++  A +       + + +     
Sbjct: 123 QEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCR 182

Query: 188 YGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEE 223
              E  ++++ L R  +     L + EK   +++EE
Sbjct: 183 IQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEE 218


>gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens]
          Length = 516

 Score = 67.4 bits (163), Expect = 4e-11
 Identities = 53/216 (24%), Positives = 96/216 (44%), Gaps = 12/216 (5%)

Query: 14  LREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVR----CPFCSKITR 69
           +RE + CPIC+E  TE    P  + CGH+ C+ C+      S+ G      CP C    +
Sbjct: 37  IREEVTCPICLELLTE----PLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQ 92

Query: 70  ITSLTQLTDNLTVLKIIDTA--GLSEAVGLLMCRSCGRRLPRQFCRSCGLVLCEPCREAD 127
             +L        +++ +     G  + +  ++C   G +L + FC+  G V+C  C E  
Sbjct: 93  PGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKL-QLFCQEDGKVICWLC-ERS 150

Query: 128 HQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDLQARYKAVLQE 187
            +  GH T  V+E A+E +  F E L +L+    E ++  A +       + + +     
Sbjct: 151 QEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCR 210

Query: 188 YGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEE 223
              E  ++++ L R  +     L + EK   +++EE
Sbjct: 211 IQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEE 246


>gi|51477690 tripartite motif-containing 6 and tripartite
           motif-containing 34 [Homo sapiens]
          Length = 842

 Score = 67.4 bits (163), Expect = 4e-11
 Identities = 53/216 (24%), Positives = 96/216 (44%), Gaps = 12/216 (5%)

Query: 14  LREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVR----CPFCSKITR 69
           +RE + CPIC+E  TE    P  + CGH+ C+ C+      S+ G      CP C    +
Sbjct: 37  IREEVTCPICLELLTE----PLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQ 92

Query: 70  ITSLTQLTDNLTVLKIIDTA--GLSEAVGLLMCRSCGRRLPRQFCRSCGLVLCEPCREAD 127
             +L        +++ +     G  + +  ++C   G +L + FC+  G V+C  C E  
Sbjct: 93  PGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKL-QLFCQEDGKVICWLC-ERS 150

Query: 128 HQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDLQARYKAVLQE 187
            +  GH T  V+E A+E +  F E L +L+    E ++  A +       + + +     
Sbjct: 151 QEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCR 210

Query: 188 YGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEE 223
              E  ++++ L R  +     L + EK   +++EE
Sbjct: 211 IQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEE 246



 Score = 59.7 bits (143), Expect = 8e-09
 Identities = 59/238 (24%), Positives = 102/238 (42%), Gaps = 31/238 (13%)

Query: 2   AAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCL---EKLLASSING 58
           ++A AS + L+   EV  CPIC+E  TE    P  L CGH++CR C+    K   +S+ G
Sbjct: 352 SSAMASKILLNVQEEVT-CPICLELLTE----PLSLDCGHSLCRACITVSNKEAVTSMGG 406

Query: 59  -VRCPFC------SKITRITSLTQLTDNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQF 111
              CP C        +     L  + + L  +K+    G        +C   G +L   F
Sbjct: 407 KSSCPVCGISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRD----LCDHHGEKL-LLF 461

Query: 112 CRSCGLVLCEPCREADHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALE 171
           C+    V+C  C E   +  GH T+  +E        F E   +L+ ++  L++ +   E
Sbjct: 462 CKEDRKVICWLC-ERSQEHRGHHTVLTEEV-------FKECQEKLQAVLKRLKKEEEEAE 513

Query: 172 GVSKDLQARYKAVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEEQSYLLN 229
            +  D++    +   +   E +R+Q E  + R        E ++   ++ EE+   L+
Sbjct: 514 KLEADIREEKTSWKYQVQTERQRIQTEFDQLRSILNN---EEQRELQRLEEEEKKTLD 568


>gi|157426898 tripartite motif-containing 10 isoform 1 [Homo
           sapiens]
          Length = 481

 Score = 66.2 bits (160), Expect = 9e-11
 Identities = 58/233 (24%), Positives = 98/233 (42%), Gaps = 30/233 (12%)

Query: 6   ASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLL----ASSINGVRC 61
           AS  ++ +L + + CPIC  +  E    P  + CGH  CR CL +              C
Sbjct: 2   ASAASVTSLADEVNCPICQGTLRE----PVTIDCGHNFCRACLTRYCEIPGPDLEESPTC 57

Query: 62  PFCSKITRITS------LTQLTDNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSC 115
           P C +  R  S      L  + +N+  L+++ T GL E     +C+  G ++   FC   
Sbjct: 58  PLCKEPFRPGSFRPNWQLANVVENIERLQLVSTLGLGEED---VCQEHGEKI-YFFCEDD 113

Query: 116 GLVLCEPCREADHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSK 175
            + LC  CREA      H    +++AA   R    + L  LR+   E+Q        +  
Sbjct: 114 EMQLCVVCREAGEHAT-HTMRFLEDAAAPYREQIHKCLKCLRKEREEIQE-------IQS 165

Query: 176 DLQARYKAVLQEYGHEERRVQDELARSRKFFTGS----LAEVEKSNSQVVEEQ 224
               R + +L +   + ++V  E A  RKF        LA++E  +  ++ ++
Sbjct: 166 RENKRMQVLLTQVSTKRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQR 218


>gi|157426896 tripartite motif-containing 10 isoform 2 [Homo
           sapiens]
          Length = 395

 Score = 66.2 bits (160), Expect = 9e-11
 Identities = 58/233 (24%), Positives = 98/233 (42%), Gaps = 30/233 (12%)

Query: 6   ASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLL----ASSINGVRC 61
           AS  ++ +L + + CPIC  +  E    P  + CGH  CR CL +              C
Sbjct: 2   ASAASVTSLADEVNCPICQGTLRE----PVTIDCGHNFCRACLTRYCEIPGPDLEESPTC 57

Query: 62  PFCSKITRITS------LTQLTDNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSC 115
           P C +  R  S      L  + +N+  L+++ T GL E     +C+  G ++   FC   
Sbjct: 58  PLCKEPFRPGSFRPNWQLANVVENIERLQLVSTLGLGEED---VCQEHGEKI-YFFCEDD 113

Query: 116 GLVLCEPCREADHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSK 175
            + LC  CREA      H    +++AA   R    + L  LR+   E+Q        +  
Sbjct: 114 EMQLCVVCREAGEHAT-HTMRFLEDAAAPYREQIHKCLKCLRKEREEIQE-------IQS 165

Query: 176 DLQARYKAVLQEYGHEERRVQDELARSRKFFTGS----LAEVEKSNSQVVEEQ 224
               R + +L +   + ++V  E A  RKF        LA++E  +  ++ ++
Sbjct: 166 RENKRMQVLLTQVSTKRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQR 218


>gi|4508005 tripartite motif-containing 26 [Homo sapiens]
          Length = 539

 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 70/277 (25%), Positives = 121/277 (43%), Gaps = 42/277 (15%)

Query: 6   ASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVRCPFCS 65
           A+   L +L E + C IC++   +    P  + CGH  CR C   +   S +   CP C 
Sbjct: 2   ATSAPLRSLEEEVTCSICLDYLRD----PVTIDCGHVFCRSCTTDVRPISGSRPVCPLCK 57

Query: 66  K------ITRITSLTQLTDNLTVLKIIDTAGLSEAV----GLLMCRSCGRRLPRQFCRSC 115
           K      I  +  L  L +N+  LK+       E         +C     +L   +C   
Sbjct: 58  KPFKKENIRPVWQLASLVENIERLKVDKGRQPGEVTREQQDAKLCERHREKL-HYYCEDD 116

Query: 116 GLVLCEPCREA-DHQPPGHCTLPVKEAAEERRRDFGEKLTRLR----ELMGELQRRKAAL 170
           G +LC  CRE+ +H+P  H  + +++AA+  R      L+ LR    ++ G   + +A +
Sbjct: 117 GKLLCVMCRESREHRP--HTAVLMEKAAQPHREKILNHLSTLRRDRDKIQGFQAKGEADI 174

Query: 171 EGVSKDLQARYKAVLQEY--GHE-----ERRVQDELARSRKFFTGSLAEVEKSNSQVVEE 223
               K LQ + + ++ E+  GH+     E  + ++LA+  +  T      EK  S+ V E
Sbjct: 175 LAALKKLQDQRQYIVAEFEQGHQFLREREEHLLEQLAKLEQELTEGR---EKFKSRGVGE 231

Query: 224 QSYL-LNIAEVQAVSRCDYFLAKIKQADVALLEETAD 259
            + L L I+E++          K +Q    L+++T D
Sbjct: 232 LARLALVISELE---------GKAQQPAAELMQDTRD 259


>gi|37622899 ring finger protein 137 [Homo sapiens]
          Length = 485

 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 60/254 (23%), Positives = 116/254 (45%), Gaps = 33/254 (12%)

Query: 11  LDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLL----ASSINGVRCPFCSK 66
           ++A+ E + CPICM    E    P  + CGH+ C  CL  L      S   G  CP C  
Sbjct: 7   VEAIVEEVACPICMTFLRE----PMSIDCGHSFCHSCLSGLWEIPGESQNWGYTCPLCRA 62

Query: 67  ITRITSLTQLTDNLTVLKIIDTAGLSEAVGLL--MCRSCGRRLPRQFCRSCGLVLCEPCR 124
             +  +L        V++ +    L   +GL   +C   G +L + FC+   L++CE C 
Sbjct: 63  PVQPRNLRPNWQLANVVEKVRLLRLHPGMGLKGDLCERHGEKL-KMFCKEDVLIMCEACS 121

Query: 125 EA-DHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGEL------QRRKAALEGVSKDL 177
           ++ +H+   H  +P+++ A E + +  E L  L++   E       +R++ A   +  + 
Sbjct: 122 QSPEHE--AHSVVPMEDVAWEYKWELHEALEHLKKEQEEAWKLEVGERKRTATWKIQVET 179

Query: 178 Q--------ARYKAVLQEYGHEERRVQDELARSRKFFTGSLAE----VEKSNSQVVEEQS 225
           +         +Y+ +L++     R++  E+A +        AE    +E ++S+++++  
Sbjct: 180 RKQSIVWEFEKYQRLLEKKQPPHRQLGAEVAAALASLQREAAETMQKLELNHSELIQQSQ 239

Query: 226 YLLN-IAEVQAVSR 238
            L   IAE++  S+
Sbjct: 240 VLWRMIAELKERSQ 253


>gi|223890259 midline 2 isoform 2 [Homo sapiens]
          Length = 705

 Score = 63.9 bits (154), Expect = 4e-10
 Identities = 69/296 (23%), Positives = 111/296 (37%), Gaps = 61/296 (20%)

Query: 2   AAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASS------ 55
           A+     L ++ L   L CPIC+E F +    P LL C H++C  C  ++L SS      
Sbjct: 12  ASGGLFSLKMETLESELTCPICLELFED----PLLLPCAHSLCFSCAHRILVSSCSSGES 67

Query: 56  ---INGVRCPFCSKITRIT--SLTQLTDNLTVLKIID----------------------- 87
              I   +CP C  +  +    L  L  N+T+  IID                       
Sbjct: 68  IEPITAFQCPTCRYVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYR 127

Query: 88  --TAGLSEAVGLLMCRSCGRRLPRQFCRSCGLVLCEPCREADHQPPGHCTLPVKEAAEER 145
             TA  SE +    C     R   + C +C +  C+ C  A H        P K+     
Sbjct: 128 PTTAMSSERIACQFCEQDPPRDAVKTCITCEVSYCDRCLRATH--------PNKKPFTSH 179

Query: 146 RRDFGEKLTRLRELMG-ELQRRKAALEGVSKD--LQARYKAVLQEYGHEERRVQDELARS 202
           R       T LR +   + +  K  +  VS D  + A  K V +   H+   + D   + 
Sbjct: 180 RLVEPVPDTHLRGITCLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKL 239

Query: 203 RKFFTGSLAEVEKSNSQVVEEQSYLLNIA----------EVQAVSRCDYFLAKIKQ 248
           ++    +L  + K NS++  + + L+ I           E + +  CD  +  I+Q
Sbjct: 240 KQTLEMNLTNLVKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQ 295


>gi|223890257 midline 2 isoform 1 [Homo sapiens]
          Length = 735

 Score = 63.9 bits (154), Expect = 4e-10
 Identities = 69/296 (23%), Positives = 111/296 (37%), Gaps = 61/296 (20%)

Query: 2   AAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASS------ 55
           A+     L ++ L   L CPIC+E F +    P LL C H++C  C  ++L SS      
Sbjct: 12  ASGGLFSLKMETLESELTCPICLELFED----PLLLPCAHSLCFSCAHRILVSSCSSGES 67

Query: 56  ---INGVRCPFCSKITRIT--SLTQLTDNLTVLKIID----------------------- 87
              I   +CP C  +  +    L  L  N+T+  IID                       
Sbjct: 68  IEPITAFQCPTCRYVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYR 127

Query: 88  --TAGLSEAVGLLMCRSCGRRLPRQFCRSCGLVLCEPCREADHQPPGHCTLPVKEAAEER 145
             TA  SE +    C     R   + C +C +  C+ C  A H        P K+     
Sbjct: 128 PTTAMSSERIACQFCEQDPPRDAVKTCITCEVSYCDRCLRATH--------PNKKPFTSH 179

Query: 146 RRDFGEKLTRLRELMG-ELQRRKAALEGVSKD--LQARYKAVLQEYGHEERRVQDELARS 202
           R       T LR +   + +  K  +  VS D  + A  K V +   H+   + D   + 
Sbjct: 180 RLVEPVPDTHLRGITCLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKL 239

Query: 203 RKFFTGSLAEVEKSNSQVVEEQSYLLNIA----------EVQAVSRCDYFLAKIKQ 248
           ++    +L  + K NS++  + + L+ I           E + +  CD  +  I+Q
Sbjct: 240 KQTLEMNLTNLVKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQ 295


>gi|55953112 ret finger protein 2 isoform 2 [Homo sapiens]
          Length = 410

 Score = 63.9 bits (154), Expect = 4e-10
 Identities = 70/278 (25%), Positives = 128/278 (46%), Gaps = 44/278 (15%)

Query: 11  LDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSING-------VRCPF 63
           ++ L E L CPIC   F +    P++L C H  C++CLE +L  S+          +CP 
Sbjct: 4   MELLEEDLTCPICCSLFDD----PRVLPCSHNFCKKCLEGILEGSVRNSLWRPAPFKCPT 59

Query: 64  CSKITRITSLTQLTDNLTVLKIIDTAG-LSEAVGLLMCRSCGRRLPRQFCRSCGLVLCEP 122
           C K T  T +  L  N ++  I++    +  +  + +C+    +    FC +   ++C  
Sbjct: 60  CRKETSATGINSLQVNYSLKGIVEKYNKIKISPKMPVCKGHLGQPLNIFCLTDMQLICGI 119

Query: 123 C-READHQPPGHCTLPVKEAAEERRRDF------------GEKLTRLRELMGELQRRKAA 169
           C    +H     C+  +++A  + R  F            G+ L+RL  L  E  +RK +
Sbjct: 120 CATRGEHTKHVFCS--IEDAYAQERDAFESLFQSFETWRRGDALSRLDTL--ETSKRK-S 174

Query: 170 LEGVSKDLQARYKAVLQEYGHEERRVQDELARSRKFFTGSLA-------EVEKSNSQVVE 222
           L+ ++KD   + K   ++  H   + ++E+     F T  LA       E+ K N+ +++
Sbjct: 175 LQLLTKD-SDKVKEFFEKLQHTLDQKKNEILSD--FETMKLAVMQAYDPEINKLNT-ILQ 230

Query: 223 EQSYLLNIAEV-QAVSRCDYFLAKIKQ--ADVALLEET 257
           EQ    NIAE  + VS    FL ++++    + +++ET
Sbjct: 231 EQRMAFNIAEAFKDVSEPIVFLQQMQEFREKIKVIKET 268


>gi|47132524 ret finger protein 2 isoform 1 [Homo sapiens]
          Length = 407

 Score = 63.9 bits (154), Expect = 4e-10
 Identities = 70/278 (25%), Positives = 128/278 (46%), Gaps = 44/278 (15%)

Query: 11  LDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSING-------VRCPF 63
           ++ L E L CPIC   F +    P++L C H  C++CLE +L  S+          +CP 
Sbjct: 1   MELLEEDLTCPICCSLFDD----PRVLPCSHNFCKKCLEGILEGSVRNSLWRPAPFKCPT 56

Query: 64  CSKITRITSLTQLTDNLTVLKIIDTAG-LSEAVGLLMCRSCGRRLPRQFCRSCGLVLCEP 122
           C K T  T +  L  N ++  I++    +  +  + +C+    +    FC +   ++C  
Sbjct: 57  CRKETSATGINSLQVNYSLKGIVEKYNKIKISPKMPVCKGHLGQPLNIFCLTDMQLICGI 116

Query: 123 C-READHQPPGHCTLPVKEAAEERRRDF------------GEKLTRLRELMGELQRRKAA 169
           C    +H     C+  +++A  + R  F            G+ L+RL  L  E  +RK +
Sbjct: 117 CATRGEHTKHVFCS--IEDAYAQERDAFESLFQSFETWRRGDALSRLDTL--ETSKRK-S 171

Query: 170 LEGVSKDLQARYKAVLQEYGHEERRVQDELARSRKFFTGSLA-------EVEKSNSQVVE 222
           L+ ++KD   + K   ++  H   + ++E+     F T  LA       E+ K N+ +++
Sbjct: 172 LQLLTKD-SDKVKEFFEKLQHTLDQKKNEILSD--FETMKLAVMQAYDPEINKLNT-ILQ 227

Query: 223 EQSYLLNIAEV-QAVSRCDYFLAKIKQ--ADVALLEET 257
           EQ    NIAE  + VS    FL ++++    + +++ET
Sbjct: 228 EQRMAFNIAEAFKDVSEPIVFLQQMQEFREKIKVIKET 265


>gi|16445412 ret finger protein 2 isoform 1 [Homo sapiens]
          Length = 407

 Score = 63.9 bits (154), Expect = 4e-10
 Identities = 70/278 (25%), Positives = 128/278 (46%), Gaps = 44/278 (15%)

Query: 11  LDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSING-------VRCPF 63
           ++ L E L CPIC   F +    P++L C H  C++CLE +L  S+          +CP 
Sbjct: 1   MELLEEDLTCPICCSLFDD----PRVLPCSHNFCKKCLEGILEGSVRNSLWRPAPFKCPT 56

Query: 64  CSKITRITSLTQLTDNLTVLKIIDTAG-LSEAVGLLMCRSCGRRLPRQFCRSCGLVLCEP 122
           C K T  T +  L  N ++  I++    +  +  + +C+    +    FC +   ++C  
Sbjct: 57  CRKETSATGINSLQVNYSLKGIVEKYNKIKISPKMPVCKGHLGQPLNIFCLTDMQLICGI 116

Query: 123 C-READHQPPGHCTLPVKEAAEERRRDF------------GEKLTRLRELMGELQRRKAA 169
           C    +H     C+  +++A  + R  F            G+ L+RL  L  E  +RK +
Sbjct: 117 CATRGEHTKHVFCS--IEDAYAQERDAFESLFQSFETWRRGDALSRLDTL--ETSKRK-S 171

Query: 170 LEGVSKDLQARYKAVLQEYGHEERRVQDELARSRKFFTGSLA-------EVEKSNSQVVE 222
           L+ ++KD   + K   ++  H   + ++E+     F T  LA       E+ K N+ +++
Sbjct: 172 LQLLTKD-SDKVKEFFEKLQHTLDQKKNEILSD--FETMKLAVMQAYDPEINKLNT-ILQ 227

Query: 223 EQSYLLNIAEV-QAVSRCDYFLAKIKQ--ADVALLEET 257
           EQ    NIAE  + VS    FL ++++    + +++ET
Sbjct: 228 EQRMAFNIAEAFKDVSEPIVFLQQMQEFREKIKVIKET 265


>gi|47132521 ret finger protein 2 isoform 1 [Homo sapiens]
          Length = 407

 Score = 63.9 bits (154), Expect = 4e-10
 Identities = 70/278 (25%), Positives = 128/278 (46%), Gaps = 44/278 (15%)

Query: 11  LDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSING-------VRCPF 63
           ++ L E L CPIC   F +    P++L C H  C++CLE +L  S+          +CP 
Sbjct: 1   MELLEEDLTCPICCSLFDD----PRVLPCSHNFCKKCLEGILEGSVRNSLWRPAPFKCPT 56

Query: 64  CSKITRITSLTQLTDNLTVLKIIDTAG-LSEAVGLLMCRSCGRRLPRQFCRSCGLVLCEP 122
           C K T  T +  L  N ++  I++    +  +  + +C+    +    FC +   ++C  
Sbjct: 57  CRKETSATGINSLQVNYSLKGIVEKYNKIKISPKMPVCKGHLGQPLNIFCLTDMQLICGI 116

Query: 123 C-READHQPPGHCTLPVKEAAEERRRDF------------GEKLTRLRELMGELQRRKAA 169
           C    +H     C+  +++A  + R  F            G+ L+RL  L  E  +RK +
Sbjct: 117 CATRGEHTKHVFCS--IEDAYAQERDAFESLFQSFETWRRGDALSRLDTL--ETSKRK-S 171

Query: 170 LEGVSKDLQARYKAVLQEYGHEERRVQDELARSRKFFTGSLA-------EVEKSNSQVVE 222
           L+ ++KD   + K   ++  H   + ++E+     F T  LA       E+ K N+ +++
Sbjct: 172 LQLLTKD-SDKVKEFFEKLQHTLDQKKNEILSD--FETMKLAVMQAYDPEINKLNT-ILQ 227

Query: 223 EQSYLLNIAEV-QAVSRCDYFLAKIKQ--ADVALLEET 257
           EQ    NIAE  + VS    FL ++++    + +++ET
Sbjct: 228 EQRMAFNIAEAFKDVSEPIVFLQQMQEFREKIKVIKET 265


>gi|5730009 ret finger protein [Homo sapiens]
          Length = 513

 Score = 63.2 bits (152), Expect = 7e-10
 Identities = 44/170 (25%), Positives = 76/170 (44%), Gaps = 10/170 (5%)

Query: 12  DALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVRCPFCSKI---T 68
           + L++   CP+C++ F E    P +L CGH IC  CL +   ++   V CP C +     
Sbjct: 8   ECLQQETTCPVCLQYFAE----PMMLDCGHNICCACLARCWGTAETNVSCPQCRETFPQR 63

Query: 69  RITSLTQLTDNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSCGLVLCEPC-READ 127
            +     L +   ++K + T   S   G +      R   + +C    + +C  C R  +
Sbjct: 64  HMRPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICVVCDRSRE 123

Query: 128 HQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDL 177
           H+  GH  LP++EA E  +     +L  L+ +    +RR+A  E    +L
Sbjct: 124 HR--GHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAEL 171


>gi|62865604 tripartite motif protein 31 [Homo sapiens]
          Length = 425

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 56/227 (24%), Positives = 100/227 (44%), Gaps = 30/227 (13%)

Query: 6   ASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVRCPFCS 65
           AS   ++ L+E + CPIC++       +P  + CGH  C +C+ ++  +S    +CP C 
Sbjct: 2   ASGQFVNKLQEEVICPICLDILQ----KPVTIDCGHNFCLKCITQIGETSCGFFKCPLCK 57

Query: 66  KITRITSLTQLTDNLTVLKIIDTAGLSEAVGLLMCRSCGR--RLPRQFCRSCGLVLCEPC 123
              R  ++   +    +++ I     SE        +C R   +   FC   G  LC  C
Sbjct: 58  TSVRKNAIRFNSLLRNLVEKIQALQASEVQSKRKEATCPRHQEMFHYFCEDDGKFLCFVC 117

Query: 124 REA-DHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDLQARYK 182
           RE+ DH+   H    ++EAA+  +    E++  L++   E  + KA  +GV      R  
Sbjct: 118 RESKDHK--SHNVSLIEEAAQNYQGQIQEQIQVLQQKEKETVQVKA--QGVH-----RVD 168

Query: 183 AVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEEQSYLLN 229
               +  HE++R+              L E E  +  + EE+++LL+
Sbjct: 169 VFTDQVEHEKQRI--------------LTEFELLHQVLEEEKNFLLS 201


>gi|169202726 PREDICTED: similar to ring finger protein 18 isoform 1
           [Homo sapiens]
          Length = 452

 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 61/215 (28%), Positives = 93/215 (43%), Gaps = 38/215 (17%)

Query: 11  LDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVRCPF---CSKI 67
           L   +  L CPICM  F +    P  + CGH+ CR C        +N    PF   CS+ 
Sbjct: 6   LQVFQRELICPICMNYFID----PVTIDCGHSFCRPCF------YLNWKDSPFLVQCSEC 55

Query: 68  TRITSLTQLTDNLTVLKIIDTAGLSEAVGLLMCRS-----CG--RRLPRQFCRSCGLVLC 120
           T+ T    L  N+   K+   A L+  V L +  S     CG  R   + FC     +LC
Sbjct: 56  TKSTGQINLKTNIHFKKM---ASLARKVSLWLFLSSEEQMCGTHRETKKMFCEVDRSLLC 112

Query: 121 EPCREA-DHQPPGHCTLPVKEAAEERRRDFGEKLTRL--------RELMGELQRRKAALE 171
             C  + +H+   HC  P++ AAEE +    +K+  L        R L  E  R +   +
Sbjct: 113 LLCSSSQEHRDHRHC--PIESAAEEHQEKLLQKMQSLWEKACENHRNLNVETTRTRCWKD 170

Query: 172 GVSKDLQARYKAVLQE---YGHEERRVQDELARSR 203
            V+  L+A  +A  Q+   + HEE +   E+ + +
Sbjct: 171 YVNLRLEA-IRAEYQKMPAFHHEEEKHNLEMLKKK 204


>gi|239755488 PREDICTED: similar to ring finger protein 18 isoform 2
           [Homo sapiens]
          Length = 446

 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 61/215 (28%), Positives = 93/215 (43%), Gaps = 38/215 (17%)

Query: 11  LDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVRCPF---CSKI 67
           L   +  L CPICM  F +    P  + CGH+ CR C        +N    PF   CS+ 
Sbjct: 6   LQVFQRELICPICMNYFID----PVTIDCGHSFCRPCF------YLNWKDSPFLVQCSEC 55

Query: 68  TRITSLTQLTDNLTVLKIIDTAGLSEAVGLLMCRS-----CG--RRLPRQFCRSCGLVLC 120
           T+ T    L  N+   K+   A L+  V L +  S     CG  R   + FC     +LC
Sbjct: 56  TKSTGQINLKTNIHFKKM---ASLARKVSLWLFLSSEEQMCGTHRETKKMFCEVDRSLLC 112

Query: 121 EPCREA-DHQPPGHCTLPVKEAAEERRRDFGEKLTRL--------RELMGELQRRKAALE 171
             C  + +H+   HC  P++ AAEE +    +K+  L        R L  E  R +   +
Sbjct: 113 LLCSSSQEHRDHRHC--PIESAAEEHQEKLLQKMQSLWEKACENHRNLNVETTRTRCWKD 170

Query: 172 GVSKDLQARYKAVLQE---YGHEERRVQDELARSR 203
            V+  L+A  +A  Q+   + HEE +   E+ + +
Sbjct: 171 YVNLRLEA-IRAEYQKMPAFHHEEEKHNLEMLKKK 204


>gi|169203362 PREDICTED: similar to ring finger protein 18 [Homo
           sapiens]
          Length = 452

 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 61/215 (28%), Positives = 93/215 (43%), Gaps = 38/215 (17%)

Query: 11  LDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVRCPF---CSKI 67
           L   +  L CPICM  F +    P  + CGH+ CR C        +N    PF   CS+ 
Sbjct: 6   LQVFQRELICPICMNYFID----PVTIDCGHSFCRPCF------YLNWKDSPFLVQCSEC 55

Query: 68  TRITSLTQLTDNLTVLKIIDTAGLSEAVGLLMCRS-----CG--RRLPRQFCRSCGLVLC 120
           T+ T    L  N+   K+   A L+  V L +  S     CG  R   + FC     +LC
Sbjct: 56  TKSTGQINLKTNIHFKKM---ASLARKVSLWLFLSSEEQMCGTHRETKKMFCEVDRSLLC 112

Query: 121 EPCREA-DHQPPGHCTLPVKEAAEERRRDFGEKLTRL--------RELMGELQRRKAALE 171
             C  + +H+   HC  P++ AAEE +    +K+  L        R L  E  R +   +
Sbjct: 113 LLCSSSQEHRDHRHC--PIESAAEEHQEKLLQKMQSLWEKACENHRNLNVETTRTRCWKD 170

Query: 172 GVSKDLQARYKAVLQE---YGHEERRVQDELARSR 203
            V+  L+A  +A  Q+   + HEE +   E+ + +
Sbjct: 171 YVNLRLEA-IRAEYQKMPAFHHEEEKHNLEMLKKK 204


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.135    0.407 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,469,771
Number of Sequences: 37866
Number of extensions: 1195965
Number of successful extensions: 5014
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 91
Number of HSP's successfully gapped in prelim test: 328
Number of HSP's that attempted gapping in prelim test: 4390
Number of HSP's gapped (non-prelim): 701
length of query: 653
length of database: 18,247,518
effective HSP length: 109
effective length of query: 544
effective length of database: 14,120,124
effective search space: 7681347456
effective search space used: 7681347456
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press