Guide to the Human Genome
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Search of human proteins with 150378545

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo
sapiens]
         (987 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens]  1942   0.0  
gi|26051278 nuclear pore membrane protein 121 [Homo sapiens]         1881   0.0  
gi|239743232 PREDICTED: hypothetical protein XP_002342775 [Homo ...  1598   0.0  
gi|239754624 PREDICTED: similar to hCG1998564 [Homo sapiens]          679   0.0  
gi|253683544 POM121 membrane glycoprotein-like 2 [Homo sapiens]       627   e-179
gi|112421134 hypothetical protein LOC23742 [Homo sapiens]             192   1e-48
gi|239742580 PREDICTED: similar to Putative POM121-like protein ...   162   2e-39
gi|239742514 PREDICTED: similar to Putative POM121-like protein ...   161   2e-39
gi|239757688 PREDICTED: similar to POM121-like 1, partial [Homo ...   150   6e-36
gi|23510406 POMZP3 fusion protein isoform 2 [Homo sapiens]            149   1e-35
gi|111160500 POMZP3 fusion protein isoform 1 [Homo sapiens]           149   1e-35
gi|33946327 nucleoporin 214kDa [Homo sapiens]                         145   2e-34
gi|116284392 mucin 2 precursor [Homo sapiens]                         142   2e-33
gi|163965366 nascent polypeptide-associated complex alpha subuni...   124   6e-28
gi|167736355 mucin 4 isoform a [Homo sapiens]                         122   2e-27
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]      121   3e-27
gi|91982772 mucin 17 [Homo sapiens]                                   121   4e-27
gi|151301154 mucin 6, gastric [Homo sapiens]                          119   1e-26
gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]             118   3e-26
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                  117   7e-26
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                   117   7e-26
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...   116   1e-25
gi|161019170 mucin 5AC [Homo sapiens]                                 110   8e-24
gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapi...   110   8e-24
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                  108   2e-23
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                  108   2e-23
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]        108   2e-23
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                       107   4e-23
gi|89276766 trophinin isoform 5 [Homo sapiens]                        107   6e-23
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]       102   2e-21

>gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens]
          Length = 987

 Score = 1942 bits (5030), Expect = 0.0
 Identities = 987/987 (100%), Positives = 987/987 (100%)

Query: 1   MVCSPVTVRIAPPDRRFSRSAIPEQIISSTLSSPSSNAPDPCAKETVLSALKEKKKKRTV 60
           MVCSPVTVRIAPPDRRFSRSAIPEQIISSTLSSPSSNAPDPCAKETVLSALKEKKKKRTV
Sbjct: 1   MVCSPVTVRIAPPDRRFSRSAIPEQIISSTLSSPSSNAPDPCAKETVLSALKEKKKKRTV 60

Query: 61  EEEDQIFLDGQENKRRRHDSSGSGHSAFEPLVASGVPASFVPKPGSLKRGLNSQSSDDHL 120
           EEEDQIFLDGQENKRRRHDSSGSGHSAFEPLVASGVPASFVPKPGSLKRGLNSQSSDDHL
Sbjct: 61  EEEDQIFLDGQENKRRRHDSSGSGHSAFEPLVASGVPASFVPKPGSLKRGLNSQSSDDHL 120

Query: 121 NKRSRSSSMSSLTGAYTSGIPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRS 180
           NKRSRSSSMSSLTGAYTSGIPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRS
Sbjct: 121 NKRSRSSSMSSLTGAYTSGIPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRS 180

Query: 181 QTPERPAKKIREEELCHHSSSSTPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQRK 240
           QTPERPAKKIREEELCHHSSSSTPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQRK
Sbjct: 181 QTPERPAKKIREEELCHHSSSSTPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQRK 240

Query: 241 RKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTET 300
           RKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTET
Sbjct: 241 RKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTET 300

Query: 301 PPTTQPSFTFTLPAAATASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEAL 360
           PPTTQPSFTFTLPAAATASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEAL
Sbjct: 301 PPTTQPSFTFTLPAAATASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEAL 360

Query: 361 SPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAE 420
           SPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAE
Sbjct: 361 SPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAE 420

Query: 421 TATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTP 480
           TATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTP
Sbjct: 421 TATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTP 480

Query: 481 PGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTA 540
           PGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTA
Sbjct: 481 PGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTA 540

Query: 541 PLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFG 600
           PLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFG
Sbjct: 541 PLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFG 600

Query: 601 APQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTL 660
           APQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTL
Sbjct: 601 APQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTL 660

Query: 661 ATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKP 720
           ATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKP
Sbjct: 661 ATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKP 720

Query: 721 ALTPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVPAHVPTPIQPTFGGATHSAFGLKAT 780
           ALTPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVPAHVPTPIQPTFGGATHSAFGLKAT
Sbjct: 721 ALTPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVPAHVPTPIQPTFGGATHSAFGLKAT 780

Query: 781 ASAFGAPASSQPAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGS 840
           ASAFGAPASSQPAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGS
Sbjct: 781 ASAFGAPASSQPAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGS 840

Query: 841 AAPAGSGSFGINVATPGSSATTGAFSFGAGQSGSTATSTPFTGGLGQNALGTTGQSTPFA 900
           AAPAGSGSFGINVATPGSSATTGAFSFGAGQSGSTATSTPFTGGLGQNALGTTGQSTPFA
Sbjct: 841 AAPAGSGSFGINVATPGSSATTGAFSFGAGQSGSTATSTPFTGGLGQNALGTTGQSTPFA 900

Query: 901 FNVGSTTESKPVFGGTATPTFGQNTPAPGVGTSGSSLSFGASSAPAQGFVGVGPFGSAAP 960
           FNVGSTTESKPVFGGTATPTFGQNTPAPGVGTSGSSLSFGASSAPAQGFVGVGPFGSAAP
Sbjct: 901 FNVGSTTESKPVFGGTATPTFGQNTPAPGVGTSGSSLSFGASSAPAQGFVGVGPFGSAAP 960

Query: 961 SFSIGAGSKTPGARQRLQARRQHTRKK 987
           SFSIGAGSKTPGARQRLQARRQHTRKK
Sbjct: 961 SFSIGAGSKTPGARQRLQARRQHTRKK 987


>gi|26051278 nuclear pore membrane protein 121 [Homo sapiens]
          Length = 984

 Score = 1881 bits (4872), Expect = 0.0
 Identities = 962/987 (97%), Positives = 967/987 (97%), Gaps = 3/987 (0%)

Query: 1   MVCSPVTVRIAPPDRRFSRSAIPEQIISSTLSSPSSNAPDPCAKETVLSALKEKKKKRTV 60
           MVCSPVTVRIAPPDRRFSRSAIPEQIISSTLSSPSSNAPDPCAKETVLSALKEK+KKRTV
Sbjct: 1   MVCSPVTVRIAPPDRRFSRSAIPEQIISSTLSSPSSNAPDPCAKETVLSALKEKEKKRTV 60

Query: 61  EEEDQIFLDGQENKRRRHDSSGSGHSAFEPLVASGVPASFVPKPGSLKRGLNSQSSDDHL 120
           EEEDQIFLDGQENKRRRHDSSGSGHSAFEPLVA+GVPASFVPKPGSLKRGLNSQSSDDHL
Sbjct: 61  EEEDQIFLDGQENKRRRHDSSGSGHSAFEPLVANGVPASFVPKPGSLKRGLNSQSSDDHL 120

Query: 121 NKRSRSSSMSSLTGAYTSGIPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRS 180
           NKRSRSSSMSSLTGAY SGIPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRS
Sbjct: 121 NKRSRSSSMSSLTGAYASGIPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRS 180

Query: 181 QTPERPAKKIREEELCHHSSSSTPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQRK 240
           QTPERPAKKIREEELCHHSSSSTPLAAD+ESQGEKAADTTPRKKQNSNSQSTPGSSGQRK
Sbjct: 181 QTPERPAKKIREEELCHHSSSSTPLAADRESQGEKAADTTPRKKQNSNSQSTPGSSGQRK 240

Query: 241 RKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTET 300
           RKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTET
Sbjct: 241 RKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTET 300

Query: 301 PPTTQPSFTFTLPAAATASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEAL 360
           PP TQPSFTFTLPAAA ASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEAL
Sbjct: 301 PPITQPSFTFTLPAAAPASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEAL 360

Query: 361 SPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAE 420
           SPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAE
Sbjct: 361 SPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAE 420

Query: 421 TATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTP 480
           TATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSA PMFKPIFTAPPKSEKEGPTP
Sbjct: 421 TATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSAPPMFKPIFTAPPKSEKEGPTP 480

Query: 481 PGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTA 540
           PGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTA
Sbjct: 481 PGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTA 540

Query: 541 PLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFG 600
           PLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFG
Sbjct: 541 PLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFG 600

Query: 601 APQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTL 660
           APQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSL TAVPTATSSSAADFSGFGSTL
Sbjct: 601 APQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLHTAVPTATSSSAADFSGFGSTL 660

Query: 661 ATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKP 720
           ATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKP
Sbjct: 661 ATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKP 720

Query: 721 ALTPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVPAHVPTPIQPTFGGATHSAFGLKAT 780
           AL PSFGSSFTFGNSA  APA APTPAP S IK+VPA+VPTPI P FGGATHSAFGLKAT
Sbjct: 721 ALAPSFGSSFTFGNSA--APAAAPTPAPPSMIKVVPAYVPTPIHPIFGGATHSAFGLKAT 778

Query: 781 ASAFGAPASSQPAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGS 840
           ASAFGAPASSQPAFGGSTAVF FGAATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGS
Sbjct: 779 ASAFGAPASSQPAFGGSTAVF-FGAATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGS 837

Query: 841 AAPAGSGSFGINVATPGSSATTGAFSFGAGQSGSTATSTPFTGGLGQNALGTTGQSTPFA 900
           AAPAGSGSFGINVATPGSS TTGAFSFGAGQSGSTATSTPF GGLGQNALGTTGQSTPFA
Sbjct: 838 AAPAGSGSFGINVATPGSSTTTGAFSFGAGQSGSTATSTPFAGGLGQNALGTTGQSTPFA 897

Query: 901 FNVGSTTESKPVFGGTATPTFGQNTPAPGVGTSGSSLSFGASSAPAQGFVGVGPFGSAAP 960
           FNV STTESKPVFGGTATPTFG NTPAPGVGTSGSSLSFGASSAPAQGFVGV PFGSAA 
Sbjct: 898 FNVSSTTESKPVFGGTATPTFGLNTPAPGVGTSGSSLSFGASSAPAQGFVGVAPFGSAAL 957

Query: 961 SFSIGAGSKTPGARQRLQARRQHTRKK 987
           SFSIGAGSKTPGARQRLQARRQHTRKK
Sbjct: 958 SFSIGAGSKTPGARQRLQARRQHTRKK 984


>gi|239743232 PREDICTED: hypothetical protein XP_002342775 [Homo
           sapiens]
          Length = 834

 Score = 1598 bits (4138), Expect = 0.0
 Identities = 812/829 (97%), Positives = 816/829 (98%), Gaps = 2/829 (0%)

Query: 159 SQLWKRNGPSSSPFSSPASSRSQTPERPAKKIREEELCHHSSSSTPLAADKESQGEKAAD 218
           S+LWKRNGPSSSPFSSPASSRSQTPERPAKKIREEE+CHHSSSSTPLAADKESQGEKAAD
Sbjct: 8   SELWKRNGPSSSPFSSPASSRSQTPERPAKKIREEEMCHHSSSSTPLAADKESQGEKAAD 67

Query: 219 TTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKAS 278
           TTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKAS
Sbjct: 68  TTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKAS 127

Query: 279 LQWFNQALEDKSDAASNSVTETPPTTQPSFTFTLPAAATASPPTSLLAPSTNPLLESLKK 338
           LQWFNQALEDKSDAASNSVTETPP TQPSFTFTLPAAA ASPPTSLLAPSTNPLLESLKK
Sbjct: 128 LQWFNQALEDKSDAASNSVTETPPITQPSFTFTLPAAAPASPPTSLLAPSTNPLLESLKK 187

Query: 339 MQTPPSLPPCPESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLG 398
           MQTPPSLPPCPESAGAATTEALSPPKTP+LLPPLGLSQSGPPGLLPSPSFDS PPTTLLG
Sbjct: 188 MQTPPSLPPCPESAGAATTEALSPPKTPNLLPPLGLSQSGPPGLLPSPSFDSNPPTTLLG 247

Query: 399 LIPAPSMVPATDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASS 458
           LIPAPSMVPATDTKAPPTLQAET TKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASS
Sbjct: 248 LIPAPSMVPATDTKAPPTLQAETTTKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASS 307

Query: 459 ASPMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPAS 518
           ASPMFKPIFTAPPKSEKEGPTPPGPSV+ATAPSSSSLPTTTSTTAPTFQPVFSSMGPPAS
Sbjct: 308 ASPMFKPIFTAPPKSEKEGPTPPGPSVSATAPSSSSLPTTTSTTAPTFQPVFSSMGPPAS 367

Query: 519 VPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSV 578
           VPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSV
Sbjct: 368 VPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSV 427

Query: 579 SSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSL 638
           SSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSL
Sbjct: 428 SSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSL 487

Query: 639 PTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSY 698
           PTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSY
Sbjct: 488 PTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSY 547

Query: 699 PGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVPAH 758
           PGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSA  APA APTPAP S IKIVPAH
Sbjct: 548 PGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSA--APAAAPTPAPPSMIKIVPAH 605

Query: 759 VPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAATSSGFGATTQTA 818
           VPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAATSSGFGATTQTA
Sbjct: 606 VPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAATSSGFGATTQTA 665

Query: 819 SSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATTGAFSFGAGQSGSTATS 878
           SSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATTGAFSFGAGQSGSTATS
Sbjct: 666 SSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATTGAFSFGAGQSGSTATS 725

Query: 879 TPFTGGLGQNALGTTGQSTPFAFNVGSTTESKPVFGGTATPTFGQNTPAPGVGTSGSSLS 938
           TPF GGLGQNALGTTGQSTPFAFNVGSTTESKPVFGGTATPTFG NTPAPGVGTSGSSLS
Sbjct: 726 TPFAGGLGQNALGTTGQSTPFAFNVGSTTESKPVFGGTATPTFGLNTPAPGVGTSGSSLS 785

Query: 939 FGASSAPAQGFVGVGPFGSAAPSFSIGAGSKTPGARQRLQARRQHTRKK 987
           FGASSAPAQGFVGV PFGSAAPSFSIGAGSKT GARQRLQARRQHTRKK
Sbjct: 786 FGASSAPAQGFVGVAPFGSAAPSFSIGAGSKTLGARQRLQARRQHTRKK 834


>gi|239754624 PREDICTED: similar to hCG1998564 [Homo sapiens]
          Length = 526

 Score =  679 bits (1751), Expect = 0.0
 Identities = 343/349 (98%), Positives = 346/349 (99%)

Query: 1   MVCSPVTVRIAPPDRRFSRSAIPEQIISSTLSSPSSNAPDPCAKETVLSALKEKKKKRTV 60
           MVCSPVTVRIAPPDRRFSRSAIPEQIISSTLSSPSSNAPDPCAKETVLSALKEK+KKRTV
Sbjct: 129 MVCSPVTVRIAPPDRRFSRSAIPEQIISSTLSSPSSNAPDPCAKETVLSALKEKEKKRTV 188

Query: 61  EEEDQIFLDGQENKRRRHDSSGSGHSAFEPLVASGVPASFVPKPGSLKRGLNSQSSDDHL 120
           EEEDQIFLDGQENKRRRHDSSGSGHSAFEPLVA+GVPASFVPKPGSLKRGLNSQSSDDHL
Sbjct: 189 EEEDQIFLDGQENKRRRHDSSGSGHSAFEPLVANGVPASFVPKPGSLKRGLNSQSSDDHL 248

Query: 121 NKRSRSSSMSSLTGAYTSGIPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRS 180
           NKRSRSSSMSSLTGAY SGIPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRS
Sbjct: 249 NKRSRSSSMSSLTGAYASGIPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRS 308

Query: 181 QTPERPAKKIREEELCHHSSSSTPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQRK 240
           QTPERPAKKIREEELCHHSSSSTPLAAD+ESQGEKAADTTPRKKQNSNSQSTPGSSGQRK
Sbjct: 309 QTPERPAKKIREEELCHHSSSSTPLAADRESQGEKAADTTPRKKQNSNSQSTPGSSGQRK 368

Query: 241 RKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTET 300
           RKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTET
Sbjct: 369 RKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTET 428

Query: 301 PPTTQPSFTFTLPAAATASPPTSLLAPSTNPLLESLKKMQTPPSLPPCP 349
           PP TQPSFTFTLPAAA ASPPTSLLAPSTNPLLESLKKMQTPPSLPPCP
Sbjct: 429 PPITQPSFTFTLPAAAPASPPTSLLAPSTNPLLESLKKMQTPPSLPPCP 477


>gi|253683544 POM121 membrane glycoprotein-like 2 [Homo sapiens]
          Length = 1035

 Score =  627 bits (1616), Expect = e-179
 Identities = 429/995 (43%), Positives = 527/995 (52%), Gaps = 82/995 (8%)

Query: 2    VCSPVTVRIAPPDRRFSRSAIPEQIISSTLSSPSSNAPDPCAKETVLSALKEKKKKRTVE 61
            + SPVT+RI PPD+R   S  PE +I+     PS    DPC+KETVL AL+E +K +   
Sbjct: 114  IWSPVTIRITPPDQRVPPSTSPEDVIALAGLPPSEELADPCSKETVLRALRECRKGKGRL 173

Query: 62   EEDQIFLDGQENKRRRHDSSGSGHSAFEPLVASGVPASFVPKPGSLKRGLNSQSSDDHLN 121
            EE  +F +  ++KRR   S  +  SAF+PL+ +G   SFVP+PG LKR L+S  SD  L 
Sbjct: 174  EEP-LFPESLDSKRR---SPETRPSAFKPLMKNGTLTSFVPRPGPLKRSLHSWGSDHSLT 229

Query: 122  KRSRSSSMSSLTGAYTSGIPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRSQ 181
            KR   SSMSSL   Y  G  SS RNAI SSYSS R  S  WKR+ PS S          +
Sbjct: 230  KRPNCSSMSSLASIYRGGTLSSKRNAIGSSYSSCRNFSDPWKRSVPSVS---------FE 280

Query: 182  TPERPAKKIREEELCHHSSSSTPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQRKR 241
            TPE P KK   E+ CH  SS  PL +D ES G                     SSGQ+ +
Sbjct: 281  TPEWPIKK---EKSCHRPSSPVPLVSDFESLGGSE------------------SSGQQNQ 319

Query: 242  KVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETP 301
            K+  LPS     ++  PPPQLGY+++ E+L L KKA LQ  N A ED ++  ++   ET 
Sbjct: 320  KIPQLPSSPENLVSEIPPPQLGYAVSDENLTLGKKAELQVSNNAGEDTTEVNTDPFPETW 379

Query: 302  PTTQPSFTFTLPAAATASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALS 361
               QPS +  LP++ T       L    NP LE+L+KMQ        P+S G AT+ A S
Sbjct: 380  LAIQPSLSLALPSSETD------LTQGANPQLENLRKMQKSLGPLASPQSTGEATSVAHS 433

Query: 362  PPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPP-TLQAE 420
            P KTPSL  P G SQS    LLP  S DSKP  T + L P    +P TDT  PP T QA+
Sbjct: 434  PLKTPSLPTPPGCSQSE---LLPGTSPDSKPTATFILLTPTSPTLPVTDTTWPPSTSQAD 490

Query: 421  TATKPQATSAPSPAPKQSFLFG-----TQNTSPSSPAAPAASSASPMFKPIFTAPPKSEK 475
             +  P     P+P   QS L G     T + S S+P  P A+SA  M KPI      SE 
Sbjct: 491  RS--PMPPDPPAPPTIQSTLLGMVSSPTSHLSASAP--PDATSAHLMLKPILGPLHNSEI 546

Query: 476  EGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFF-KQTTTPAT 534
               +    SVTA A S SSL T   T  PTF+P+F S+ P  + P+ APF  KQT  P T
Sbjct: 547  GSSSYSRISVTAAASSISSLSTIQGTLTPTFKPIFGSIDPLKTTPMIAPFSSKQTPPPFT 606

Query: 535  APTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAAS 594
              +T    F GL  ATS V   T AS S DS  KP   FG+ +V+S+  +T +  +T  +
Sbjct: 607  HASTHH--FHGLVKATSVVMSTTLASTSKDSVFKPPLDFGVVNVTSAVGNTYSVPSTCDT 664

Query: 595  QPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFS 654
              FL G  QA  A FTPA G IF     P +PT  TVT F+Q L + V  +  SS A+F 
Sbjct: 665  --FLLGTAQAFRADFTPATGFIFPPHHHPTIPTVHTVTMFTQVLSSVVQISPRSSTANFR 722

Query: 655  GFGSTLATSAPATSSQPTLTFSNTS-TPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQ 713
            G GS L  SA  +++    T S ++ TP    P GSS++ P P   GANPQPAFGA  GQ
Sbjct: 723  GMGSPLPASALVSTNWLASTPSISNLTPAITSPLGSSSRPPFPLSQGANPQPAFGATNGQ 782

Query: 714  PPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVPAHVPTPIQPTFGGATHS 773
              G ++PAL PS  SSF FG+SA   P   PTPA                QP F   T S
Sbjct: 783  KQGPSQPALMPSVSSSFLFGSSAVALPTPMPTPA----------------QPAFISTTQS 826

Query: 774  AFG-LKATASAFGAPASSQPAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSVFGSTTP 832
            A G L  +AS    PAS+    GG  A F    A+++GF    QT  SG+  SVFGS  P
Sbjct: 827  ALGCLTPSASTSQTPASTWSGIGGIPAGFPISQASTTGFRIVIQTHQSGAFGSVFGSRAP 886

Query: 833  SPFTFGGSAAPAGSGSFGINVATPGSSATTGAFSFGAGQSGSTATSTPFTGGLGQNALGT 892
             PFTFGG   P      GI +  P  S T+GAFS GA  SG+T T  PF  G  QN  G 
Sbjct: 887  QPFTFGGFVTPMDCDESGIIMTGPDMSPTSGAFSIGALPSGTTNTMIPFGKGWSQNTEGL 946

Query: 893  TGQSTPFAFNVGSTTESKPVFGGTATPTFGQNTPAPGVGTSGSSLSFGASSAPAQGFVGV 952
                T F+   GS +  K     T  P   QNTP PG   +GSS+ FG    PAQG VG 
Sbjct: 947  PSHRTAFSLGRGSISARK-----TMAP-IAQNTPVPGQAKAGSSVGFGMPFPPAQGSVGR 1000

Query: 953  GPFGSAAPSFSIGAGSKTPGARQRLQARRQHTRKK 987
            GPF S+A SFSIGA SKTP  R++  +RR H  KK
Sbjct: 1001 GPFRSSASSFSIGAKSKTPKNREKGHSRRHHAYKK 1035


>gi|112421134 hypothetical protein LOC23742 [Homo sapiens]
          Length = 1156

 Score =  192 bits (488), Expect = 1e-48
 Identities = 279/1093 (25%), Positives = 425/1093 (38%), Gaps = 236/1093 (21%)

Query: 5    PVTVRIAPPDRRFSRSAIPEQIISSTLSSPSSNAPDPCAKETVLSALKEKKK-------K 57
            P +VRI PP R F            TL  PS   P   A++ + + L E+ +       +
Sbjct: 111  PSSVRIPPPSRMF------------TLLLPSPREPAVKARKPIPATLLEETEVWAQEGPR 158

Query: 58   RTVEEEDQIFLDGQENKRRRHDSSGSGHSAFEPLVASGVPASFVPKPGSLKRGLNSQSSD 117
            R  ++ED + ++G+++++R   SSG   S        G  ASF   PG L+  +  + S+
Sbjct: 159  RVKKDEDPVQIEGEDDEKRTPLSSGEASSTSRSQGTQGDVASFRCSPGPLEGNVYHKFSE 218

Query: 118  DHLNKRSRSSSMSS-LTGAYTSGIPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPA 176
            + +++++++S  SS L G            A+ S++S       L K +  +++P   PA
Sbjct: 219  NSMSEKAQASPASSCLEGP-----------AMPSTHSQAGCARHLGKPDPDATAP-PEPA 266

Query: 177  SSRSQTPERPAKKIREEELCHHS-SSSTPLAADKESQGEKAADTTPRKKQNSNSQSTPGS 235
               S   ++ A ++  EE    S     PL + K    EK     PR      S + P +
Sbjct: 267  VGCSLLQQKLAAEVLNEEPPPSSLGLPIPLMSGKRMPDEKPFCIPPR------SAAPPRA 320

Query: 236  SGQR--KRKVQ---LLPS--------RRGEQLTLPPPPQLGYSITAEDL-DLEKKASLQW 281
            +  R  KRK+    LLP          RGE   LPPP +L       DL  LEK    + 
Sbjct: 321  ARNRPCKRKMSIPLLLPLPPSLPLLWDRGE---LPPPAKLPCLSVEGDLHTLEKSPEYKR 377

Query: 282  FNQALEDKSDAASNSVTETPPTTQPSFTFTLPAAATAS-PPTSLLAPSTNPL-LESLKKM 339
             ++ LEDK++  +NS       TQP+ +F+ P   T S P T+  +  + PL +  L  +
Sbjct: 378  NSRILEDKTETMTNS-----SITQPAPSFSQPVQTTDSLPLTTYTSQVSAPLPIPDLADL 432

Query: 340  QTPPSLPPCPESAGAATTE---ALSPPKTPSLLP-------------------------P 371
             T P + P P  +     +   A + P +P  LP                         P
Sbjct: 433  ATGPLILPIPPLSTTPKMDEKIAFTIPNSPLALPADLVPILGDQSNEKGGSYNSVVGAAP 492

Query: 372  LGLSQSGPPGLLP------------SPSFDSKPPTTLLGLIPAP---------------S 404
            L      PP   P            S   DS PP + L L+P P               S
Sbjct: 493  LTSDPPTPPSSTPSFKPPVTRESPISMCVDSPPPLSFLTLLPVPSTGTSVITSKPMNSTS 552

Query: 405  MVPATDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNTS-----PSSPAAPAASSA 459
            ++    T A   L ++TA  P+  +  + AP Q  +F +  +S     P+S    +A   
Sbjct: 553  VISTVTTNASAHLTSQTAVDPEVVNMDTTAPSQVVIFTSSLSSRVSSLPNSQIHCSAEQR 612

Query: 460  SPMFKPIFTAPPKSEKEGPTPPGPSV-TATAPSSSSLPTTTSTTAPTFQPVFSSMGPPAS 518
             P    ++T+P            P +   T PS + L    +T  P F+   +  G P  
Sbjct: 613  HPGKTSVYTSPL-----------PFIFHNTTPSFNQLFGKEATPQPKFE---APDGQPQK 658

Query: 519  VPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAF------- 571
              LP+      + P   P  T+ L    ++A+S+  PI + +  T   SK          
Sbjct: 659  ASLPSACV-FLSLPIIPPPDTSTLVNSASTASSSKPPIETNAMHTTPPSKAVILQSASVS 717

Query: 572  -----------GFGINSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFG 620
                       G G    S ++ S   ST+  A    +     AS     P      +FG
Sbjct: 718  KKYLPFYLGLPGSGNTQPSGNTASVQGSTSLPAQS--VRAPATASNHPLNPGATPQPKFG 775

Query: 621  KPPALPTTTTVTTFSQ--SLPTAVPTATSSSAADFSGFGSTLATSAPATS-SQPTLTFS- 676
             P      T++ +     SLP  VP  T           STL +SA A S S+P +  S 
Sbjct: 776  APDGPQQKTSLPSAHDFLSLPIMVPPDT-----------STLVSSASAASLSKPAIDTSD 824

Query: 677  -NTSTPTFNIPFGSSAKSPLPSY-------PG------------ANPQPAFGAAEGQPP- 715
             NT+ P+  +   S+  S    Y       PG            A    +F A   + P 
Sbjct: 825  MNTTPPSKTVILQSTFVSRKEEYIRFYMGLPGSGNTLHSDSIASAQVSTSFPAQADRRPT 884

Query: 716  -GAAKPALTPSFG--------------SSFTFGNSAAPAPATAPTPAPASTIKIVPAHVP 760
              ++ P  T S                SSF  GN A PAP    T +P+           
Sbjct: 885  TTSSHPLNTGSISHSTLGATDGQQKSDSSFILGNPATPAPVIGLT-SPS----------- 932

Query: 761  TPIQPTFGGATHSAFG-LKATASAFGAPASSQPAFGGSTAVFSFGAATSSGFGATTQTAS 819
              +QP  G      F  L +  +A G P +++P  G + + F  G A +SGF   T    
Sbjct: 933  --VQPLSGSIIPPGFAELTSPYTALGTPVNAEPVEGHNASAFPNGTAKTSGFRIATGMPG 990

Query: 820  SGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATTGAFSFGAGQSGSTATST 879
            +G S+ + G+T P P    G   P   GS G +++ PG S+T+G  + G GQSG+ +T++
Sbjct: 991  TGDSTLLVGNTIPGPQVIMGPGTPMDGGSIGFSMSAPGPSSTSGELNIGQGQSGTPSTTS 1050

Query: 880  PFTGGLGQNALGTTGQSTPFAFNVGSTTESKPVFGGTATPTF--GQNTP----APGVGTS 933
             F    GQ A   TG S   A    S     PVFG T+   +  G + P      G+G  
Sbjct: 1051 VFP--FGQAAWDPTGHSMAAAPQGASNI---PVFGYTSAAAYIPGLDPPTQNSCSGMGGD 1105

Query: 934  GSSLSFGASSAPA 946
            G+    G    PA
Sbjct: 1106 GTRSIVGGPCVPA 1118


>gi|239742580 PREDICTED: similar to Putative POM121-like protein
           1-like [Homo sapiens]
          Length = 897

 Score =  162 bits (409), Expect = 2e-39
 Identities = 213/778 (27%), Positives = 318/778 (40%), Gaps = 115/778 (14%)

Query: 61  EEEDQIFLDGQENKRRRHDSSGSGHSAFEPLVASGVPASFVPKPGSLKRGLNSQSSDDHL 120
           +++D    +  +++R   + +G   SAF PL  +G P+ FVP+PG L+  L++QSS+   
Sbjct: 4   QDKDPRVQENPDDQRTVPEVTGDARSAFWPLRDNGGPSPFVPRPGPLQTDLHAQSSEIRY 63

Query: 121 NKRSRSSSMSSLTGAYTSGIPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRS 180
           N  S++S  SS          S+ RNAI+SSYSST G+  L +R GP        ASSR 
Sbjct: 64  NHTSQTSWTSS----------STKRNAISSSYSSTGGLPGLKQRRGP--------ASSRC 105

Query: 181 QTPERPAKKIREEELCHHSSSSTPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQ-R 239
           Q     +K + E+     SS  T        + EK ADT P +       S      + R
Sbjct: 106 QLTLSYSKTVSEDRPQAVSSGHT--------RCEKGADTAPGQTIAPTGGSPRSQDSRPR 157

Query: 240 KRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQAL--EDKSDAASNSV 297
           +RK+ LLP RRGE L LPPP +LGY +TAEDL LEK+ + Q  N AL  EDK      ++
Sbjct: 158 RRKIPLLPRRRGEPLMLPPPLELGYRVTAEDLHLEKETAFQRINSALHVEDK------AI 211

Query: 298 TETPPTTQPSFTF-TLPAAATASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAAT 356
            +  P ++PS T  +L   A+  PP S  AP+ +   +  K       + P    A AA 
Sbjct: 212 PDCRP-SRPSHTLSSLATGASGGPPVS-KAPTMDAQQDRPKSQDCLGLVAPL---ASAAE 266

Query: 357 TEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPT 416
             + +P       PP  L  S  P  LP+ S+ S+    +  LIPA     + D     T
Sbjct: 267 VPSTAPVSGKKHRPPGPLFSSSDP--LPATSYHSRDTAQVTSLIPATFTAASRDAGMRRT 324

Query: 417 LQAETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKE 476
             A  A    AT+AP P+   +      N     P+   AS+         TA  ++++ 
Sbjct: 325 RSAPAA----ATAAPPPSTLNNTSGSLLNAVDGGPSHFLASA---------TAAARAQRS 371

Query: 477 GPTPPGPSVTATAPS----SSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTP 532
                  S T+   S    ++S  +++ ++    Q +    G PAS           T  
Sbjct: 372 EVRYNQRSQTSRTRSCLKRNASSSSSSHSSTEGLQELKRRRG-PASSHCQLAHSSSNTVS 430

Query: 533 ATAPTTTAPLFTGLASATSA-VAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTAT 591
              P   +   +G      A  AP  + +P   S    A    IN  S+  V     +  
Sbjct: 431 EDGPQAVS---SGHRCENKAGTAPGQTLAPRGGSPRSQASRPHIN--SALYVEDKAISDC 485

Query: 592 AASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAA 651
             S+P    +  A+ AS           G PP               PT         + 
Sbjct: 486 RPSRPSHTLSSLATGAS-----------GGPPV-----------SKAPTMDAQQDRPKSQ 523

Query: 652 DFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAE 711
           D  G  + LA++A   S+ P                G   + P P +  ++P PA   + 
Sbjct: 524 DCLGLVAPLASAAEVPSTAPV--------------SGKKHRPPGPLFSSSDPLPA--TSS 567

Query: 712 GQPPGAAKPALTPSFGSSFTFGNSAAPAPATAP-TPAPASTIKIVPAHVPTPIQPTFGGA 770
                A   +L P   ++FT  +  A    T P T APA+    +P   P+ + PT G  
Sbjct: 568 HSRDSAQVTSLIP---ATFTAASRDAGMRRTRPGTSAPAAAAAALP---PSTLNPTSGSL 621

Query: 771 THSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSVFG 828
            ++  G     S F A A++      S   ++  + TS       + ASS S SS  G
Sbjct: 622 LNAVDG---GPSHFLASATAAARAQRSEVRYNQRSQTSRTRSCLKRNASSSSHSSTEG 676



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 74/309 (23%), Positives = 108/309 (34%), Gaps = 81/309 (26%)

Query: 95  GVPASFVPKPGSLKRGLNSQSSDDHLNKRSRSSSMSSLTGAYTSGIPSSSRNAITSSYSS 154
           G P+ F+    +  R   +Q S+   N+RS++S   S             RNA +SS+SS
Sbjct: 627 GGPSHFLASATAAAR---AQRSEVRYNQRSQTSRTRSCL----------KRNASSSSHSS 673

Query: 155 TRGISQLWKRNGPSSSPFSSPASSRSQTPERPAKKIREEELCHHSSSSTPLAADKESQGE 214
           T G+ +L +R GP+SS      SS +   E   + +     C + + + P          
Sbjct: 674 TEGLQELKRRRGPASSHCQLAHSSSNTVSEDGPQAVSSGHRCENKAGTAP---------- 723

Query: 215 KAADTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLE 274
                                               G+ L     P+ GY          
Sbjct: 724 ------------------------------------GQTLA----PRGGYP--------R 735

Query: 275 KKASLQWFNQALEDKSDAASNSVTETPPTTQPSFTFTLPAAATASPPTSLLAPSTNPLLE 334
            +AS    N AL  +  A S+     P  T  S    L   A+  PP S  AP+ +   +
Sbjct: 736 SQASRPRINSALHVEDKAISDCRPSRPSHTLSS----LATGASGGPPVS-KAPTMDAQQD 790

Query: 335 SLKKMQTPPSLPPCPESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPT 394
             K       L P   +A  ++T  +S  K     PP  L  S  P  LP+ S  S    
Sbjct: 791 RPKSQDCLGLLAPLASAAEVSSTAPVSGKKH---RPPGPLFSSSDP--LPATSSHSGDSA 845

Query: 395 TLLGLIPAP 403
               LIPAP
Sbjct: 846 QDTSLIPAP 854


>gi|239742514 PREDICTED: similar to Putative POM121-like protein
           1-like [Homo sapiens]
          Length = 896

 Score =  161 bits (408), Expect = 2e-39
 Identities = 194/669 (28%), Positives = 275/669 (41%), Gaps = 93/669 (13%)

Query: 61  EEEDQIFLDGQENKRRRHDSSGSGHSAFEPLVASGVPASFVPKPGSLKRGLNSQSSDDHL 120
           +++D    +  ++ R   + +G   SAF PL  +G  + FVP+PG L+  L++QSS+   
Sbjct: 4   QDKDPRVQENPDDHRTVPEVTGDARSAFWPLRDNGGLSPFVPRPGPLQTDLHAQSSEIRY 63

Query: 121 NKRSRSSSMSSLTGAYTSGIPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRS 180
           N+ S++S  SS          S+ RNAI+SSYSST G+  L +R GP        ASSR 
Sbjct: 64  NQTSQTSWTSS----------STKRNAISSSYSSTGGLPGLKQRRGP--------ASSRC 105

Query: 181 QTPERPAKKIREEELCHHSSSSTPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQ-R 239
           Q     +K + E+     SS  T        + EKAADT P +       S    + + R
Sbjct: 106 QLTLSYSKTVSEDRPQAVSSGHT--------RCEKAADTAPGQTLAPRGGSPRSQASRPR 157

Query: 240 KRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTE 299
           +RK+ LLPSRRGE L +PPP +LGY +TAEDL LEK+A+ Q  N AL  +  A S+    
Sbjct: 158 RRKIPLLPSRRGEPLMMPPPLELGYRVTAEDLHLEKQAAFQRINSALHVEDKAISDCRPS 217

Query: 300 TPPTTQPSFTFTLPAAATASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEA 359
            P  T  S    L   A+  PP S  AP+ +   +  K       + P   +A  ++T  
Sbjct: 218 RPSHTLSS----LATGASGGPPVS-KAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAP 272

Query: 360 LSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQA 419
           +S  K     PP  L  S  P  LP+ S  S+    +  +IPAP    + D     T  A
Sbjct: 273 VSGKKQ---RPPGPLFSSSDP--LPATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRSA 327

Query: 420 ETATKPQATSAPSPA---PKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKE 476
             A    A +AP P+   P    L    +  PS   A A ++A      +     +  + 
Sbjct: 328 PAA----AAAAPPPSTLNPTSGSLLNAVDGGPSHFLASATAAARAQRSEV-----RYNQR 378

Query: 477 GPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAP 536
                  S      SSSS  +T         P       PAS           T     P
Sbjct: 379 SQISRTRSCLKRNASSSSHSSTEGL------PELKRRRGPASSHCQLAHSSSKTVSEDGP 432

Query: 537 TTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINS---VSSSSVS--------- 584
              +   T      +  AP  + +P   S    A    INS   V   ++S         
Sbjct: 433 QAVSSGHT-RCEKRADTAPGQTLAPRGGSPRSQASRPHINSALHVEDKAISDCRPSRPSH 491

Query: 585 TTTSTATAASQ-PFLFGAPQASAASFTP----AMGSIFQFGKPPALPTTTTVT------- 632
           T +S AT AS+ P +  AP   A    P     +G +        LP+T  V+       
Sbjct: 492 TLSSLATGASRGPPVSKAPTMDAQQDRPKSQDCLGLLAPLASAAELPSTAPVSGKKHRPP 551

Query: 633 --TFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTL--TFSNTSTPTFNIPFG 688
              FS S P     ATSS + D +   S +     A S    +  T   TS P       
Sbjct: 552 GPLFSSSDPL---PATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRPGTSAP------A 602

Query: 689 SSAKSPLPS 697
           ++A +P PS
Sbjct: 603 AAAAAPPPS 611



 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 96/403 (23%), Positives = 142/403 (35%), Gaps = 114/403 (28%)

Query: 95  GVPASFVPKPGSLKRGLNSQSSDDHLNKRSRSSSMSSLTGAYTSGIPSSSRNAITSSYSS 154
           G P+ F+    +  R   +Q S+   N+RS+ S   S             RNA +SS+SS
Sbjct: 353 GGPSHFLASATAAAR---AQRSEVRYNQRSQISRTRSCL----------KRNASSSSHSS 399

Query: 155 TRGISQLWKRNGPSSSPFSSPASSRSQTPERPAKKIREEELCHHSSSSTPLAADKESQGE 214
           T G+ +L +R GP        ASS  Q     +K + E+     SS  T        + E
Sbjct: 400 TEGLPELKRRRGP--------ASSHCQLAHSSSKTVSEDGPQAVSSGHT--------RCE 443

Query: 215 KAADTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLE 274
           K ADT P                      Q L  R G   +    P +  ++  ED    
Sbjct: 444 KRADTAPG---------------------QTLAPRGGSPRSQASRPHINSALHVED---- 478

Query: 275 KKASLQWFNQALEDKSDAASNSVTETPPTTQPSFTFT-LPAAATASPPTSLLAPSTNPLL 333
                                ++++  P+ +PS T + L   A+  PP S  AP+ +   
Sbjct: 479 --------------------KAISDCRPS-RPSHTLSSLATGASRGPPVSK-APTMDAQQ 516

Query: 334 ESLKKMQTPPSLPPCPESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPP 393
           +  K       L P   +A   +T  +S  K     PP  L  S  P  LP+ S  S+  
Sbjct: 517 DRPKSQDCLGLLAPLASAAELPSTAPVSGKKHR---PPGPLFSSSDP--LPATSSHSRDS 571

Query: 394 TTLLGLIPAPSMVPATDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNTSP--SSP 451
             +  +IPAP    + D                               G + T P  S+P
Sbjct: 572 AQVTSMIPAPFTAASRDA------------------------------GMRRTRPGTSAP 601

Query: 452 AAPAASSASPMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSSS 494
           AA AA+       P   +   +  EGP+    S TA A +  S
Sbjct: 602 AAAAAAPPPSTLNPTSGSLLNAVDEGPSHFLASATAAARARRS 644



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 78/326 (23%), Positives = 122/326 (37%), Gaps = 75/326 (23%)

Query: 84  GHSAFEPLVASGVPASFVPKPGSLKRGLNSQSSDDHLNK----RSRSSSMSSLTGAYTSG 139
           G SA     A+  P++  P  GSL   ++   S    +     R+R S +     + TS 
Sbjct: 597 GTSAPAAAAAAPPPSTLNPTSGSLLNAVDEGPSHFLASATAAARARRSQVRYNQRSQTSR 656

Query: 140 IPSS-SRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRSQTPERPAKKIREEELCHH 198
             S   RNA +SS+SST G+ +L +R GP+SS                         C  
Sbjct: 657 TRSCLKRNASSSSHSSTEGLQELKRRRGPASSH------------------------CQL 692

Query: 199 SSSSTPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPP 258
           + SS+   ++   Q   + DT   K     + + PG         Q L  R G   +   
Sbjct: 693 ALSSSNTVSEDGPQAVSSRDTRCEK-----ADTAPG---------QTLAPRGGSPRSQAS 738

Query: 259 PPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETPPTTQPSFTF-TLPAAAT 317
            P++  ++  ED                         ++++  P ++PS T  +L   A+
Sbjct: 739 RPRINSALHVED------------------------KAISDCRP-SRPSHTLSSLATGAS 773

Query: 318 ASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALSPPKTPSLLPPLGLSQS 377
             PP S  AP+ +   +  K       + P   +A  ++T  +S  K     PP  L  S
Sbjct: 774 GGPPVS-KAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKH---RPPGPLFSS 829

Query: 378 GPPGLLPSPSFDSKPPTTLLGLIPAP 403
             P  LP+ S  S        LIPAP
Sbjct: 830 SDP--LPATSSHSGDSAQDTSLIPAP 853


>gi|239757688 PREDICTED: similar to POM121-like 1, partial [Homo
           sapiens]
          Length = 346

 Score =  150 bits (379), Expect = 6e-36
 Identities = 124/355 (34%), Positives = 170/355 (47%), Gaps = 37/355 (10%)

Query: 38  APDPCAKETVLSALKEKKKKRTVEEEDQIFLDGQENKRRRHDSSGSGHSAFEPLVASGVP 97
           +PD C  + VL ALKE       +++D    +   ++RR  + +G   SAF PL  +G  
Sbjct: 22  SPDLCPGKIVLRALKESGAGMPEQDKDPRVQENPGDQRRVPEVTGDAPSAFRPLRDNGGL 81

Query: 98  ASFVPKPGSLKRGLNSQSSDDHLNKRSRSSSMSSLTGAYTSGIPSSSRNAITSSYSSTRG 157
           + FVP+PG L+  L++Q S+   N+ S++S  SS T          +RNAI+SSYSST G
Sbjct: 82  SPFVPRPGPLQTDLHAQRSEIRYNQTSQTSWTSSCT----------NRNAISSSYSSTGG 131

Query: 158 ISQLWKRNGPSSSPFSSPASSRSQTPERPAKKIREEELCHHSSSSTPLAADKESQGEKAA 217
           +  L +R GP+SS      SS        +K + E+     SS  T        Q EKAA
Sbjct: 132 LPGLKRRRGPASSHCQLTLSS--------SKTVSEDRPQAVSSGHT--------QCEKAA 175

Query: 218 DTTPRKKQN-SNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKK 276
           D  P +     N  ST  +S     K  LLP RRGE L LPPP +LGY +T EDLD EK+
Sbjct: 176 DIAPGQTLTLRNDSSTSEASRPSTHKFPLLPRRRGEPLMLPPPLELGYRVTVEDLDREKE 235

Query: 277 ASLQWFNQALEDKSDAASNSVTETPPTTQPSFTFTLPAAATASPPTSLLAPSTNPLLESL 336
           A+ Q  N AL+ +  A S+        + PS T +  A   +  P    A S +   E+ 
Sbjct: 236 AAFQRINSALQVEDKAISDC-----RPSWPSHTLSSLATGASGLPAVSKASSMDAQQETH 290

Query: 337 KKMQTPPSLPPCPESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSK 391
           K       L P    A AA   + +P       PP  L  S  P  LP+ S DS+
Sbjct: 291 KSQDCLGLLAPL---ASAAEVPSTAPVSGKKHRPPGPLFSSSDP--LPATSSDSQ 340



 Score = 31.2 bits (69), Expect = 5.0
 Identities = 70/335 (20%), Positives = 104/335 (31%), Gaps = 44/335 (13%)

Query: 441 FGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSSSLPTTTS 500
           FG  NT  S    P       + K      P+ +K+      P V         +P  T 
Sbjct: 14  FGVHNTRLSPDLCPGKIVLRAL-KESGAGMPEQDKD------PRVQENPGDQRRVPEVTG 66

Query: 501 TTAPTFQPVFSSMGPPASVPLPAPF------------FKQTT-TPATAPTTTAPLFTGLA 547
                F+P+  + G    VP P P             + QT+ T  T+  T     +   
Sbjct: 67  DAPSAFRPLRDNGGLSPFVPRPGPLQTDLHAQRSEIRYNQTSQTSWTSSCTNRNAISSSY 126

Query: 548 SATSAV-------APITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFG 600
           S+T  +        P +S    T S+SK        +VSS       +   A  Q     
Sbjct: 127 SSTGGLPGLKRRRGPASSHCQLTLSSSKTVSEDRPQAVSSGHTQCEKAADIAPGQTLTLR 186

Query: 601 APQASAASFTPAMGSI----FQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGF 656
              +++ +  P+         + G+P  LP    +          V        A F   
Sbjct: 187 NDSSTSEASRPSTHKFPLLPRRRGEPLMLPPPLEL-----GYRVTVEDLDREKEAAFQRI 241

Query: 657 GSTLATSAPATS----SQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEG 712
            S L     A S    S P+ T S+ +T    +P  S A S          Q   G    
Sbjct: 242 NSALQVEDKAISDCRPSWPSHTLSSLATGASGLPAVSKASSMDAQQETHKSQDCLGLLAP 301

Query: 713 QPPGAAKPALTPSFGSSF----TFGNSAAPAPATA 743
               A  P+  P  G          +S+ P PAT+
Sbjct: 302 LASAAEVPSTAPVSGKKHRPPGPLFSSSDPLPATS 336


>gi|23510406 POMZP3 fusion protein isoform 2 [Homo sapiens]
          Length = 115

 Score =  149 bits (376), Expect = 1e-35
 Identities = 82/106 (77%), Positives = 85/106 (80%), Gaps = 12/106 (11%)

Query: 1   MVCSPVTVRIAPPDRRFSRSAIPEQIISSTLSSPSSNAPDPCAKETVLSALKEKKKKRTV 60
           MVCSPVT+RIAPPDRRFSRSAIPEQIISSTLSSPSSNAPDPCAKETVLSALKEKKKKRTV
Sbjct: 1   MVCSPVTLRIAPPDRRFSRSAIPEQIISSTLSSPSSNAPDPCAKETVLSALKEKKKKRTV 60

Query: 61  EEEDQIFLDGQENKRR-RHDSSGSGHSAFEPLVASGVPASFVPKPG 105
           EEEDQIFLDGQENKR    D      SAF+           VP+PG
Sbjct: 61  EEEDQIFLDGQENKRSCLVDGLTDASSAFK-----------VPRPG 95


>gi|111160500 POMZP3 fusion protein isoform 1 [Homo sapiens]
          Length = 187

 Score =  149 bits (376), Expect = 1e-35
 Identities = 82/106 (77%), Positives = 85/106 (80%), Gaps = 12/106 (11%)

Query: 1   MVCSPVTVRIAPPDRRFSRSAIPEQIISSTLSSPSSNAPDPCAKETVLSALKEKKKKRTV 60
           MVCSPVT+RIAPPDRRFSRSAIPEQIISSTLSSPSSNAPDPCAKETVLSALKEKKKKRTV
Sbjct: 1   MVCSPVTLRIAPPDRRFSRSAIPEQIISSTLSSPSSNAPDPCAKETVLSALKEKKKKRTV 60

Query: 61  EEEDQIFLDGQENKRR-RHDSSGSGHSAFEPLVASGVPASFVPKPG 105
           EEEDQIFLDGQENKR    D      SAF+           VP+PG
Sbjct: 61  EEEDQIFLDGQENKRSCLVDGLTDASSAFK-----------VPRPG 95


>gi|33946327 nucleoporin 214kDa [Homo sapiens]
          Length = 2090

 Score =  145 bits (366), Expect = 2e-34
 Identities = 244/948 (25%), Positives = 367/948 (38%), Gaps = 159/948 (16%)

Query: 168  SSSPFSSPASSRSQTPERPAKKIREEELCHHSSSSTPLAADKE-SQGEKAADTTPRKKQN 226
            SS P+S+  +         A + ++  L +    S P  A  + S G+KA+ T    K  
Sbjct: 1141 SSVPYSTAKTPHPVLTPVAANQAKQGSLINSLKPSGPTPASGQLSSGDKASGTA---KIE 1197

Query: 227  SNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQAL 286
            +   STP +SGQ  +     PS  G    +  P        A+      K S Q    + 
Sbjct: 1198 TAVTSTPSASGQFSKPFSFSPSGTGFNFGIITPTPSSNFTAAQGATPSTKESSQPDAFSS 1257

Query: 287  EDKSDAASNSVTET-PPTTQPSFTFTLPA--AATASPPTSLLAPSTNPLLESLKKMQTPP 343
               S  +  ++ E+ PP+   S + T P   AA++S P   +APS   L  +  K++TPP
Sbjct: 1258 GGGSKPSYEAIPESSPPSGITSASNTTPGEPAASSSRP---VAPSGTALSTTSSKLETPP 1314

Query: 344  S-----LPPCP---ESAG-------------------AATTEALSPPKTPSLLPPLGLSQ 376
            S     L P     E+ G                   A++T   S   T +   P G + 
Sbjct: 1315 SKLGELLFPSSLAGETLGSFSGLRVGQADDSTKPTNKASSTSLTSTQPTKTSGVPSGFNF 1374

Query: 377  SGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAETATKPQATSAPS---- 432
            + PP L       ++PP T      + +   AT T +     +   T   ++   S    
Sbjct: 1375 TAPPVL----GKHTEPPVTSSATTTSVAPPAATSTSSTAVFGSLPVTSAGSSGVISFGGT 1430

Query: 433  --PAPKQSFLFGTQNTSPSSP--AAPAASSASPMFKPIFTAPPKSEKEGPTPPGPSVTA- 487
               A K SF FG+Q T+ + P  A P  ++A+P+     T    S     T P   ++A 
Sbjct: 1431 SLSAGKTSFSFGSQQTNSTVPPSAPPPTTAATPLPTSFPTLSFGSLLSSATTPSLPMSAG 1490

Query: 488  ---TAPSSSSLP-----TTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTT---PATAP 536
                  +SS+LP     +  S +A +      S   P + P  +   K+      PA + 
Sbjct: 1491 RSTEEATSSALPEKPGDSEVSASAASLLEEQQSAQLPQAPPQTSDSVKKEPVLAQPAVSN 1550

Query: 537  TTTAPLFTGLASATSAVAPITSASPSTDS-ASKPAFGFGI---NSVSSSSVST------- 585
            + TA   T L + ++   P T+  P   + A  PA  F +    +V+++++S+       
Sbjct: 1551 SGTAASSTSLVALSAEATPATTGVPDARTEAVPPASSFSVPGQTAVTAAAISSAGPVAVE 1610

Query: 586  TTSTATAASQPFLFG-APQASAASFTPAMGSIFQFGKPPALPTTTT---VTTFSQSLPTA 641
            T+ST  A+S   +    P A AA+F         F +PPA  +++    +T  + + P+A
Sbjct: 1611 TSSTPIASSTTSIVAPGPSAEAAAFGTVTSGSSVFAQPPAASSSSAFNQLTNNTATAPSA 1670

Query: 642  VPTATSSSAADF-SGFGSTLATSAPATSSQPTLTFSNTSTPTFNIP-------------- 686
             P     +A+   S FG    ++A   ++ P ++ S  S+P F                 
Sbjct: 1671 TPVFGQVAASTAPSLFGQQTGSTASTAAATPQVSSSGFSSPAFGTTAPGVFGQTTFGQAS 1730

Query: 687  -FGSSAKSPLP----SYPGANPQPAFGAAEGQPPGAAK-----PALTPSFGSSFTFGNSA 736
             FG SA S       S PG +  PAFG      P +        A + S  SSF+FG S+
Sbjct: 1731 VFGQSASSAASVFSFSQPGFSSVPAFGQPASSTPTSTSGSVFGAASSTSSSSSFSFGQSS 1790

Query: 737  ----------APAPATAPTPA---PASTIKIVPAHVPTPIQPTFGGATHSAFGLKATASA 783
                      + APA   +P      S      A   T     F     S FG   T S 
Sbjct: 1791 PNTGGGLFGQSNAPAFGQSPGFGQGGSVFGGTSAATTTAATSGFSFCQASGFGSSNTGSV 1850

Query: 784  FGAPASS------QPAFGGSTAVFSFG-AATSSGF-----GATTQTASS----GSSSSVF 827
            FG  AS+      Q +   S +VF  G      GF     G  +Q A++     S+S  F
Sbjct: 1851 FGQAASTGGIVFGQQSSSSSGSVFGSGNTGRGGGFFSGLGGKPSQDAANKNPFSSASGGF 1910

Query: 828  GSTTPSPFT--FGGSAAPAGSGSFGINVATPGSSATTGAFSFGAGQSGSTA---TSTPFT 882
            GST  S  +  FG S A    G    +    G    TG FS G G   S     +S   T
Sbjct: 1911 GSTATSNTSNLFGNSGAKTFGGFASSSF---GEQKPTGTFSSGGGSVASQGFGFSSPNKT 1967

Query: 883  GGLGQNAL--------GTTGQSTPFAFNVGSTTESKPVFGGTATPTFGQNTPAP-----G 929
            GG G   +        G+ G     AF  GS        G T    FG+ T A      G
Sbjct: 1968 GGFGAAPVFGSPPTFGGSPGFGGVPAF--GSAPAFTSPLGSTGGKVFGEGTAAASAGGFG 2025

Query: 930  VGTSGSSLSFG---ASSAPAQGFVG--VGPFGSAAPSFSIGAGSKTPG 972
             G+S ++ SFG   + +AP  G +      FG+ +  FS G GS T G
Sbjct: 2026 FGSSSNTTSFGTLASQNAPTFGSLSQQTSGFGTQSSGFS-GFGSGTGG 2072



 Score =  142 bits (357), Expect = 2e-33
 Identities = 245/1029 (23%), Positives = 384/1029 (37%), Gaps = 172/1029 (16%)

Query: 21   AIPEQIISSTLSSPSSNAPDPCAKETVLSALKEKKKKRTVEEEDQIFLDGQENKRRRHDS 80
            A P   + S++   ++  P P       +  K+     +++        GQ +       
Sbjct: 1133 ATPSTAMGSSVPYSTAKTPHPVLTPVAANQAKQGSLINSLKPSGPTPASGQLSS----GD 1188

Query: 81   SGSGHSAFEPLVASGVPASFVPKPGSLKRGLNSQSSDDHLNKRSRSSSMSSLTGAYTSGI 140
              SG +  E  V S   AS     G   +  +   S    N    + + SS   A     
Sbjct: 1189 KASGTAKIETAVTSTPSAS-----GQFSKPFSFSPSGTGFNFGIITPTPSSNFTAAQGAT 1243

Query: 141  PSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRSQTPERPAKKIREEELCHHSS 200
            PS+  ++   ++SS  G    ++   P SSP S   S+ + TP  PA           +S
Sbjct: 1244 PSTKESSQPDAFSSGGGSKPSYEAI-PESSPPSGITSASNTTPGEPA-----------AS 1291

Query: 201  SSTPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPP 260
            SS P+A                   +  + ST  S      K++  PS+ GE L      
Sbjct: 1292 SSRPVAP------------------SGTALSTTSS------KLETPPSKLGELL------ 1321

Query: 261  QLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETPPTTQ---PS-FTFTLPAAA 316
                S+  E L       +   + + +  + A+S S+T T PT     PS F FT P   
Sbjct: 1322 -FPSSLAGETLGSFSGLRVGQADDSTKPTNKASSTSLTSTQPTKTSGVPSGFNFTAPPVL 1380

Query: 317  T--ASPPTSLLAPSTN---PLLESLKKMQTPPSLPPCPESAGAA--------------TT 357
                 PP +  A +T+   P   S        SLP    SAG++              T+
Sbjct: 1381 GKHTEPPVTSSATTTSVAPPAATSTSSTAVFGSLPVT--SAGSSGVISFGGTSLSAGKTS 1438

Query: 358  EALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTL 417
             +    +T S +PP     S PP    +    +  PT   G + + +  P+    A  + 
Sbjct: 1439 FSFGSQQTNSTVPP-----SAPPPTTAATPLPTSFPTLSFGSLLSSATTPSLPMSAGRST 1493

Query: 418  QAETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEG 477
            +  T++        S     +     +  S   P AP  +S S   +P+   P  S   G
Sbjct: 1494 EEATSSALPEKPGDSEVSASAASLLEEQQSAQLPQAPPQTSDSVKKEPVLAQPAVSNS-G 1552

Query: 478  PTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPP-------ASVPLPAPFFKQTT 530
                  S+ A +  ++   T          P  SS   P       A++    P   +T+
Sbjct: 1553 TAASSTSLVALSAEATPATTGVPDARTEAVPPASSFSVPGQTAVTAAAISSAGPVAVETS 1612

Query: 531  TPATAPTTTAPLFTGLASATSAVAPITSAS-----PSTDSASKPAFGFGINSVSSSSVST 585
            +   A +TT+ +  G ++  +A   +TS S     P   S+S        N+ ++ S + 
Sbjct: 1613 STPIASSTTSIVAPGPSAEAAAFGTVTSGSSVFAQPPAASSSSAFNQLTNNTATAPSATP 1672

Query: 586  TTSTATAASQPFLFGAPQASAASFTPAMGSIFQFG-KPPALPTTTT----VTTFSQSLPT 640
                  A++ P LFG    S AS   A   +   G   PA  TT       TTF Q+   
Sbjct: 1673 VFGQVAASTAPSLFGQQTGSTASTAAATPQVSSSGFSSPAFGTTAPGVFGQTTFGQASVF 1732

Query: 641  AVPTATSSSAADFS--GFGSTLATSAPATSSQPTLTF------SNTSTPTFNIPFGSSAK 692
                ++++S   FS  GF S  A   PA SS PT T       +++++ + +  FG S+ 
Sbjct: 1733 GQSASSAASVFSFSQPGFSSVPAFGQPA-SSTPTSTSGSVFGAASSTSSSSSFSFGQSSP 1791

Query: 693  SPLPSYPGANPQPAFGAAEGQPPGAA-----KPALTPSFGSSFTFGNSAAPAPATAPTP- 746
            +      G +  PAFG + G   G +       A T +  S F+F  ++    +   +  
Sbjct: 1792 NTGGGLFGQSNAPAFGQSPGFGQGGSVFGGTSAATTTAATSGFSFCQASGFGSSNTGSVF 1851

Query: 747  -APASTIKIVPAHVPTPIQPTF--------GGATHSAFGLKATASA------------FG 785
               AST  IV     +    +         GG   S  G K +  A            FG
Sbjct: 1852 GQAASTGGIVFGQQSSSSSGSVFGSGNTGRGGGFFSGLGGKPSQDAANKNPFSSASGGFG 1911

Query: 786  APASSQPA--FGGSTAVFSFGAATSSGFGAT--TQTASSGSSSSV---FGSTTP------ 832
            + A+S  +  FG S A  +FG   SS FG    T T SSG  S     FG ++P      
Sbjct: 1912 STATSNTSNLFGNSGAK-TFGGFASSSFGEQKPTGTFSSGGGSVASQGFGFSSPNKTGGF 1970

Query: 833  -------SPFTFGGSAAPAGSGSFGINVATPGSSATTGAFSFGAGQSGSTATSTPFTGGL 885
                   SP TFGGS    G  +FG   A      +TG   FG G + ++A      GG 
Sbjct: 1971 GAAPVFGSPPTFGGSPGFGGVPAFGSAPAFTSPLGSTGGKVFGEGTAAASA------GGF 2024

Query: 886  GQNALGTTGQSTPFAFNVGSTTESKPVFGGTATPTFG---QNTPAPGVGTSGSSLSFGAS 942
            G    G++  +T F       +++ P FG  +  T G   Q++   G G+     SFG++
Sbjct: 2025 G---FGSSSNTTSFG---TLASQNAPTFGSLSQQTSGFGTQSSGFSGFGSGTGGFSFGSN 2078

Query: 943  SAPAQGFVG 951
            ++  QGF G
Sbjct: 2079 NSSVQGFGG 2087



 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 103/400 (25%), Positives = 147/400 (36%), Gaps = 112/400 (28%)

Query: 279 LQWFNQALEDKSDAASNSVTETPPTTQPSFTFTLPAAATASPPTSLLAPSTNPLLESLKK 338
           + W +  LED S A      E P T +          +  S P  ++   TN +  ++  
Sbjct: 336 INWESWLLEDSSRA------ELPVTDK----------SDDSLPMGVVVDYTNQVEITISD 379

Query: 339 MQTPPSLPPCPESAGAATTEALSP-------------PKTPSLLPPLGLSQSGPPGLLPS 385
            +T   LPP P     +T   L P              KTP  L   G  Q   PG  P+
Sbjct: 380 EKT---LPPAPVLMLLSTDGVLCPFYMINQNPGVKSLIKTPERLSLEGERQPKSPGSTPT 436

Query: 386 PSFDSKPPTTL-LGLIPAPSMVPATDTKAP------------PTLQA--ETATKPQAT-- 428
               S+ P  L      AP+ +P +   AP            PT+ +   ++ K  AT  
Sbjct: 437 TPTSSQAPQKLDASAAAAPASLPPSSPAAPIATFSLLPAGGAPTVFSFGSSSLKSSATVT 496

Query: 429 --------------SAPSPA--------PKQSFLFGTQNTSPSSPAAPAASSASPMFKPI 466
                         +AP P         P ++ L  T   SP +P+A + S  S  FKP 
Sbjct: 497 GEPPSYSSGSDSSKAAPGPGPSTFSFVPPSKASLAPTPAASPVAPSAASFSFGSSGFKPT 556

Query: 467 FTAPPKSEKEGPT-------PPGPSVTAT------APSSSSLPTTTSTTAPTFQPVFSSM 513
             + P      P        PP  S            +++S P ++S +AP   P  S+ 
Sbjct: 557 LESTPVPSVSAPNIAMKPSFPPSTSAVKVNLSEKFTAAATSTPVSSSQSAPPMSPFSSAS 616

Query: 514 GPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGF 573
            P AS PL  P      TP +AP ++ PL        S+V P    SPS  SA       
Sbjct: 617 KPAASGPLSHP------TPLSAPPSSVPL-------KSSVLP----SPSGRSAQ------ 653

Query: 574 GINSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAM 613
           G +S   S V  +      A++P   G+PQA   S  PA+
Sbjct: 654 GSSSPVPSMVQKSPRITPPAAKP---GSPQAK--SLQPAV 688



 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 118/446 (26%), Positives = 158/446 (35%), Gaps = 105/446 (23%)

Query: 622  PPALPTTTTVTTFSQSLPTAVPTATSSSAADFSG--FGSTLATSAPATSSQPTLTFSNTS 679
            P   P   T +     LP A P A S      S    G+++ATSA     Q      +T 
Sbjct: 1013 PRHAPVVRTPSIQPSLLPHAAPFAKSHLVHGSSPGVMGTSVATSASKIIPQGA---DSTM 1069

Query: 680  TPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKPAL----------------- 722
              T  +  G+    P PS+P + PQ A  AA  +   +  PA+                 
Sbjct: 1070 LATKTVKHGA----PSPSHPISAPQAAAAAALRRQMASQAPAVNTLTESTLKNVPQVVNV 1125

Query: 723  --------TPS--FGSSFTFGNSAAPAPATAPTPA----PASTIKIVPAHVPTPIQPTFG 768
                    TPS   GSS  +  +  P P   P  A      S I  +    PTP      
Sbjct: 1126 QELKNNPATPSTAMGSSVPYSTAKTPHPVLTPVAANQAKQGSLINSLKPSGPTPA----S 1181

Query: 769  GATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFG-AATSSGFGATTQTASS------G 821
            G   S      TA    A  S+  A G  +  FSF  + T   FG  T T SS      G
Sbjct: 1182 GQLSSGDKASGTAKIETAVTSTPSASGQFSKPFSFSPSGTGFNFGIITPTPSSNFTAAQG 1241

Query: 822  SSSSVFGSTTPSPFTFGGSAAPA---------GSGSFGINVATPGSSATTGAFSFGAGQS 872
            ++ S   S+ P  F+ GG + P+          SG    +  TPG  A + +       +
Sbjct: 1242 ATPSTKESSQPDAFSSGGGSKPSYEAIPESSPPSGITSASNTTPGEPAASSSRPVAPSGT 1301

Query: 873  GSTATS----TP--------FTGGLGQNALGT-----TGQ---STPFAFNVGST--TESK 910
              + TS    TP        F   L    LG+      GQ   ST       ST  T ++
Sbjct: 1302 ALSTTSSKLETPPSKLGELLFPSSLAGETLGSFSGLRVGQADDSTKPTNKASSTSLTSTQ 1361

Query: 911  PV--------FGGTATPTFGQNTP------------APGVGTSGSSLS-FGASSAPAQGF 949
            P         F  TA P  G++T             AP   TS SS + FG+    + G 
Sbjct: 1362 PTKTSGVPSGFNFTAPPVLGKHTEPPVTSSATTTSVAPPAATSTSSTAVFGSLPVTSAGS 1421

Query: 950  VGVGPFGSAAPSFSIGAGSKTPGARQ 975
             GV  FG    S S G  S + G++Q
Sbjct: 1422 SGVISFGGT--SLSAGKTSFSFGSQQ 1445



 Score = 54.3 bits (129), Expect = 6e-07
 Identities = 74/272 (27%), Positives = 99/272 (36%), Gaps = 28/272 (10%)

Query: 285 ALEDKSDAASNSVTETPPTTQ--PSFTFTLPAAATAS-PPTSLLAP-STNPLL------- 333
           +LE +    S   T T PT+   P       AAA AS PP+S  AP +T  LL       
Sbjct: 421 SLEGERQPKSPGSTPTTPTSSQAPQKLDASAAAAPASLPPSSPAAPIATFSLLPAGGAPT 480

Query: 334 ------ESLKKMQTPPSLPPCPESAGAATTEALSP-PKTPSLLPPLGLSQSGPPGLLP-- 384
                  SLK   T    PP   S   ++  A  P P T S +PP   S +  P   P  
Sbjct: 481 VFSFGSSSLKSSATVTGEPPSYSSGSDSSKAAPGPGPSTFSFVPPSKASLAPTPAASPVA 540

Query: 385 ----SPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAETATKPQATSAPSPAPKQSFL 440
               S SF S      L   P PS+        P    + +A K   +   + A   + +
Sbjct: 541 PSAASFSFGSSGFKPTLESTPVPSVSAPNIAMKPSFPPSTSAVKVNLSEKFTAAATSTPV 600

Query: 441 FGTQNTSPSSP----AAPAASSASPMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSSSLP 496
             +Q+  P SP    + PAAS       P+   P     +    P PS  +   SSS +P
Sbjct: 601 SSSQSAPPMSPFSSASKPAASGPLSHPTPLSAPPSSVPLKSSVLPSPSGRSAQGSSSPVP 660

Query: 497 TTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQ 528
           +    +     P      P A    PA   KQ
Sbjct: 661 SMVQKSPRITPPAAKPGSPQAKSLQPAVAEKQ 692



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 65/243 (26%), Positives = 90/243 (37%), Gaps = 23/243 (9%)

Query: 622 PPALPTTTTVTTFSQSLPTAVPTAT-----SSSAADFSGFGSTLATSAPATSSQPTLTFS 676
           P + PTT T +   Q L  +   A      SS AA  + F    A  AP   S  + +  
Sbjct: 431 PGSTPTTPTSSQAPQKLDASAAAAPASLPPSSPAAPIATFSLLPAGGAPTVFSFGSSSLK 490

Query: 677 NTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKPALTP--SFGSSFTFGN 734
           +++T T   P  SS      + PG  P         +   A  PA +P     +SF+FG+
Sbjct: 491 SSATVTGEPPSYSSGSDSSKAAPGPGPSTFSFVPPSKASLAPTPAASPVAPSAASFSFGS 550

Query: 735 SAAPAPATAPTPAPASTIKIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAF 794
           S    P    TP P+ +    P     P  P    A       K TA+A   P SS    
Sbjct: 551 SGF-KPTLESTPVPSVS---APNIAMKPSFPPSTSAVKVNLSEKFTAAATSTPVSS---- 602

Query: 795 GGSTAVFSFGAATSSGFGATTQTASSGSSSSVFG-STTPSPFTFGGSAAPAGSGSFGINV 853
                  S  A   S F + ++ A+SG  S     S  PS      S  P+ SG      
Sbjct: 603 -------SQSAPPMSPFSSASKPAASGPLSHPTPLSAPPSSVPLKSSVLPSPSGRSAQGS 655

Query: 854 ATP 856
           ++P
Sbjct: 656 SSP 658



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 62/239 (25%), Positives = 99/239 (41%), Gaps = 30/239 (12%)

Query: 530 TTPATAPTTTAP--LFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTT 587
           +TP T  ++ AP  L    A+A +++ P + A+P    +  PA G    +V S   S+  
Sbjct: 433 STPTTPTSSQAPQKLDASAAAAPASLPPSSPAAPIATFSLLPAGG--APTVFSFGSSSLK 490

Query: 588 STATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATS 647
           S+AT   +P  + +   S+ +      S F F  P       T        P A P A S
Sbjct: 491 SSATVTGEPPSYSSGSDSSKAAPGPGPSTFSFVPPSKASLAPT--------PAASPVAPS 542

Query: 648 SSAADF--SGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQP 705
           +++  F  SGF  TL ++   + S P +       P+F          P  S    N   
Sbjct: 543 AASFSFGSSGFKPTLESTPVPSVSAPNIAMK----PSF---------PPSTSAVKVNLSE 589

Query: 706 AFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTP--APASTIKIVPAHVPTP 762
            F AA    P ++  +  P    S +    AA  P + PTP  AP S++ +  + +P+P
Sbjct: 590 KFTAAATSTPVSSSQSAPPMSPFS-SASKPAASGPLSHPTPLSAPPSSVPLKSSVLPSP 647



 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 62/241 (25%), Positives = 81/241 (33%), Gaps = 34/241 (14%)

Query: 761 TPIQPTFGGATHSAFGLKATASAFGAPASSQPAF-------------GGSTAVFSFGAAT 807
           TP  PT   A       K  ASA  APAS  P+              GG+  VFSFG+++
Sbjct: 434 TPTTPTSSQAPQ-----KLDASAAAAPASLPPSSPAAPIATFSLLPAGGAPTVFSFGSSS 488

Query: 808 SSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATTGAFSF 867
                  T    S SS S      P P     S  P    S     A    + +  +FSF
Sbjct: 489 LKSSATVTGEPPSYSSGSDSSKAAPGPGPSTFSFVPPSKASLAPTPAASPVAPSAASFSF 548

Query: 868 GAGQSGSTATSTPFTGGLGQNAL-------GTTGQSTPFAFNVGSTTESKPVFGGTATPT 920
           G+     T  STP       N          T+      +    +   S PV    + P 
Sbjct: 549 GSSGFKPTLESTPVPSVSAPNIAMKPSFPPSTSAVKVNLSEKFTAAATSTPVSSSQSAPP 608

Query: 921 FGQNTPAPGVGTSG-----SSLSFGASSAPAQGFVGVGPFGSAAPSFSIGAGSKTPGARQ 975
               + A     SG     + LS   SS P +  V   P G +A     G+ S  P   Q
Sbjct: 609 MSPFSSASKPAASGPLSHPTPLSAPPSSVPLKSSVLPSPSGRSAQ----GSSSPVPSMVQ 664

Query: 976 R 976
           +
Sbjct: 665 K 665



 Score = 50.8 bits (120), Expect = 6e-06
 Identities = 80/319 (25%), Positives = 124/319 (38%), Gaps = 43/319 (13%)

Query: 412 KAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPP 471
           K P  L  E   +P++  +    P  S     Q    S+ AAPA+   S    PI T   
Sbjct: 415 KTPERLSLEGERQPKSPGSTPTTPTSSQ--APQKLDASAAAAPASLPPSSPAAPIATF-- 470

Query: 472 KSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTT 531
                   P G + T  +  SSSL ++ + T    +P   S G  +S   P P     +T
Sbjct: 471 -----SLLPAGGAPTVFSFGSSSLKSSATVTG---EPPSYSSGSDSSKAAPGP---GPST 519

Query: 532 PATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTAT 591
            +  P + A L     + T A +P+  ++ S        F FG +    +  ST   + +
Sbjct: 520 FSFVPPSKASL-----APTPAASPVAPSAAS--------FSFGSSGFKPTLESTPVPSVS 566

Query: 592 AASQPFLFGAPQASAASFTPAMGSI-FQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSA 650
           A +         A   SF P+  ++     +      T+T  + SQS P   P +++S  
Sbjct: 567 APN--------IAMKPSFPPSTSAVKVNLSEKFTAAATSTPVSSSQSAPPMSPFSSASKP 618

Query: 651 ADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAA 710
           A           SAP +S    L  S   +P+     GSS  SP+PS    +P+    AA
Sbjct: 619 AASGPLSHPTPLSAPPSS--VPLKSSVLPSPSGRSAQGSS--SPVPSMVQKSPRITPPAA 674

Query: 711 EGQPPGA--AKPALTPSFG 727
           +   P A   +PA+    G
Sbjct: 675 KPGSPQAKSLQPAVAEKQG 693


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score =  142 bits (358), Expect = 2e-33
 Identities = 174/662 (26%), Positives = 248/662 (37%), Gaps = 81/662 (12%)

Query: 298  TETPPTTQPS----FTFTLPAAATASPPTSLLA---PSTNPLLESLKKMQTPPSLPPCPE 350
            T +PPTT PS     T TLP   T SPPT+      P+T P          PP+  P P 
Sbjct: 1398 TPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPP 1457

Query: 351  SAGAATTEALSPPKTPSLLPPLGLSQSGPP---GLLPSPSFDSKPPTTLLGLIPA-PSMV 406
             +   T    + P  P+  P    +   PP      P P+    PPTT     PA  + +
Sbjct: 1458 ISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTL 1517

Query: 407  PATDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNTS---PSSPAAPAASSASPMF 463
            P T T +PPT    T T P  T+ PSP         T  T+    ++P+ P  ++ +P  
Sbjct: 1518 PPTTTPSPPT---TTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTP-- 1572

Query: 464  KPIFTAPPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPA 523
             P  T P       P+PP  + T   P+++  P TT+TT P   P  ++  PP + P+  
Sbjct: 1573 -PPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTP---PPTTTPSPPTTTPITP 1628

Query: 524  PFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSV 583
            P     T+  T P TT P  +   + T+   P T+ SP T +   P            + 
Sbjct: 1629 P-----TSTTTLPPTTTP--SPPPTTTTTPPPTTTPSPPTTTTPSPPI----------TT 1671

Query: 584  STTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVP 643
            +TT    T  S P        +    TP+  +       P+ P TTT T  S + P+  P
Sbjct: 1672 TTTPPPTTTPSSPITTTPSPPTTTMTTPSPTT------TPSSPITTTTTPSSTTTPSPPP 1725

Query: 644  T--ATSSSAADFSGFGSTLATSAPATSSQPTLTF---SNTSTPTFNIPFGSSAKSPLPSY 698
            T   T S     S   +T+ T  P T+S P  T     + + PTF+ PF S+     P  
Sbjct: 1726 TTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFS-PF-STTTPTTPCV 1783

Query: 699  PGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAP-------APATAPTPAPAST 751
            P  N     G  +   P   KP      G +   G+   P         AT     P   
Sbjct: 1784 PLCN---WTGWLDSGKPNFHKPG-----GDTELIGDVCGPGWAANISCRATMYPDVPIGQ 1835

Query: 752  I-KIVPAHVPTPI-----QPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFGA 805
            + + V   V   +         GG    AF L    +       +QP    +T   +   
Sbjct: 1836 LGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTP 1895

Query: 806  ATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATTGAF 865
             T++    TT    + + +     TT +P T   +  P  + +      T   + TT   
Sbjct: 1896 PTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 1954

Query: 866  SFGAGQSGSTATSTPFTGGLGQNALGT-TGQSTPFAFNVGSTTESKPVFGGTATPTFGQN 924
                     T T+TP T         T TG  TP    + +TT   P    T TPT G  
Sbjct: 1955 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP----TPTPT-GTQ 2009

Query: 925  TP 926
            TP
Sbjct: 2010 TP 2011



 Score =  132 bits (333), Expect = 1e-30
 Identities = 180/688 (26%), Positives = 249/688 (36%), Gaps = 111/688 (16%)

Query: 294  SNSVTETPPTTQPS----FTFTLPAAATASPPTSLLAPSTNPLLESLKKMQTPPSLPPCP 349
            + + T  PPTT PS     T T P   T SPP S    +T P   +     T PS PP  
Sbjct: 1426 TTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPIS--TTTTPPPTTTPSPPTTTPS-PPTT 1482

Query: 350  ESAGAATTEALSPP-KTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPA 408
              +   TT    PP  TPS  PP     + P      P   +  P T     P P+  P+
Sbjct: 1483 TPSPPTTTTTTPPPTTTPS--PPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPS 1540

Query: 409  TDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNTSP---SSPAAPAASSASPMFKP 465
              T  P T    T T P  T+ PSP P       T  T+P   ++P+ P  ++ SP    
Sbjct: 1541 PPTTTPITPPTSTTTLP-PTTTPSPPP-------TTTTTPPPTTTPSPPTTTTPSPPTIT 1592

Query: 466  IFTAPPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPF 525
              T PP +     TP  P+ T T P  ++ P+  +TT P   P  ++  PP + P P P 
Sbjct: 1593 TTTPPPTT-----TPSPPTTTTTTPPPTTTPSPPTTT-PITPPTSTTTLPPTTTPSPPPT 1646

Query: 526  FKQTTTPATA---PTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINS---VS 579
               T  P T    PTTT P    + + T+     T +SP T + S P       S     
Sbjct: 1647 TTTTPPPTTTPSPPTTTTP-SPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTP 1705

Query: 580  SSSVSTTT---STATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQ 636
            SS ++TTT   ST T +  P     P  +    TP+         PP    TT   T + 
Sbjct: 1706 SSPITTTTTPSSTTTPSPPPTTMTTPSPTT---TPS---------PPTTTMTTLPPTTTS 1753

Query: 637  SLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFS---NTSTPTFNIPFGSSAKS 693
            S  T  P   S +   FS F    +T+ P T   P   ++   ++  P F+ P G +   
Sbjct: 1754 SPLTTTPLPPSITPPTFSPF----STTTPTTPCVPLCNWTGWLDSGKPNFHKPGGDTELI 1809

Query: 694  PLPSYPG--AN--------PQPAFGAA----------------EGQPPGAAKPALTPSFG 727
                 PG  AN        P    G                  E Q PG   P    +F 
Sbjct: 1810 GDVCGPGWAANISCRATMYPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPM---AFC 1866

Query: 728  SSFTFG--------NSAAPAPATAPTPAPASTIKIVPAHVPTPIQPTFGGATHSAFGLKA 779
             ++                   T   P P +T  I      TP     G  T +   +  
Sbjct: 1867 LNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 1926

Query: 780  TASAFGAPASSQPAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGG 839
            T +    P  +      +T + +    T +     TQT ++ +  +   + TP+P T  G
Sbjct: 1927 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTP-TPTG 1984

Query: 840  SAAPAGSGSFGINVATPGSSATTGAFSFGAGQSGSTATSTPFTGGLGQNALGT-TGQSTP 898
            +  P  +        TP  + T             T T+TP T         T TG  TP
Sbjct: 1985 TQTPTTTPITTTTTVTPTPTPT----------GTQTPTTTPITTTTTVTPTPTPTGTQTP 2034

Query: 899  FAFNVGSTTESKPVFGGTATPTFGQNTP 926
                + +TT   P    T TPT G  TP
Sbjct: 2035 TTTPITTTTTVTP----TPTPT-GTQTP 2057



 Score =  132 bits (331), Expect = 2e-30
 Identities = 162/663 (24%), Positives = 241/663 (36%), Gaps = 89/663 (13%)

Query: 298  TETPPTTQPSFTFTLPAAATASP---PTSLLAPSTNPLLESLKKMQTP-PSLPPCPESAG 353
            T TP  TQ   T  +    T +P   PT    P+T P+  +     TP P+    P +  
Sbjct: 2117 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2176

Query: 354  AATTEALSPPKTPS-----LLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPA 408
              TT  ++P  TP+        P+  + +  P   P+P+    P TT     P  +    
Sbjct: 2177 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGTQTPTTT-----PITTTTTV 2229

Query: 409  TDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQN--------TSPSSPAAPAASSAS 460
            T T  P   Q  T T    T+  +P P  +   GTQ         T+  +P      + +
Sbjct: 2230 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQT 2286

Query: 461  PMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSSSL-----PTTTSTTAPTFQPVFSSMGP 515
            P   PI T    +    PTP G     T P +++      PT T T  PT  P+ ++   
Sbjct: 2287 PTTTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-- 2342

Query: 516  PASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGI 575
                P P P    T TP T P TT    T   + T    P T+   +T + +      G 
Sbjct: 2343 -TVTPTPTP--TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2399

Query: 576  NSVSSSSVSTTTS-----TATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTT 630
             + +++ ++TTT+     T T    P        +  + TP              PTTT 
Sbjct: 2400 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-------TQTPTTTP 2452

Query: 631  VTTFSQSLPTAVPTATSS-SAADFSGFGSTLATSAPATSSQPT---LTFSNTSTPTFNIP 686
            +TT +   PT  PT T + +    +   +   T  P  +  PT   +T + T TPT   P
Sbjct: 2453 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-PTP 2511

Query: 687  FGSS--AKSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAP 744
             G+     +P+ +     P P        P G   P  TP      T   +  P P    
Sbjct: 2512 TGTQTPTTTPITTTTTVTPTPT-------PTGTQTPTTTP-----ITTTTTVTPTPTPTG 2559

Query: 745  TPAPASTIKIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFG 804
            T  P +T  I      TP     G  T +   +  T +    P  +      +T + +  
Sbjct: 2560 TQTPTTT-PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2618

Query: 805  AATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATTGA 864
              T +     TQT ++ +  +   + TP+P T  G+  P  +        TP  + T   
Sbjct: 2619 TVTPTPTPTGTQTPTT-TPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT--- 2673

Query: 865  FSFGAGQSGSTATSTPFTGGLGQNALGT-TGQSTPFAFNVGSTTESKPVFGGTATPTFGQ 923
                      T T+TP T         T TG  TP    + +TT   P    T TPT G 
Sbjct: 2674 -------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP----TPTPT-GT 2721

Query: 924  NTP 926
             TP
Sbjct: 2722 QTP 2724



 Score =  132 bits (331), Expect = 2e-30
 Identities = 162/663 (24%), Positives = 241/663 (36%), Gaps = 89/663 (13%)

Query: 298  TETPPTTQPSFTFTLPAAATASP---PTSLLAPSTNPLLESLKKMQTP-PSLPPCPESAG 353
            T TP  TQ   T  +    T +P   PT    P+T P+  +     TP P+    P +  
Sbjct: 2439 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2498

Query: 354  AATTEALSPPKTPS-----LLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPA 408
              TT  ++P  TP+        P+  + +  P   P+P+    P TT     P  +    
Sbjct: 2499 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGTQTPTTT-----PITTTTTV 2551

Query: 409  TDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQN--------TSPSSPAAPAASSAS 460
            T T  P   Q  T T    T+  +P P  +   GTQ         T+  +P      + +
Sbjct: 2552 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQT 2608

Query: 461  PMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSSSL-----PTTTSTTAPTFQPVFSSMGP 515
            P   PI T    +    PTP G     T P +++      PT T T  PT  P+ ++   
Sbjct: 2609 PTTTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-- 2664

Query: 516  PASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGI 575
                P P P    T TP T P TT    T   + T    P T+   +T + +      G 
Sbjct: 2665 -TVTPTPTP--TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2721

Query: 576  NSVSSSSVSTTTS-----TATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTT 630
             + +++ ++TTT+     T T    P        +  + TP              PTTT 
Sbjct: 2722 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-------TQTPTTTP 2774

Query: 631  VTTFSQSLPTAVPTATSS-SAADFSGFGSTLATSAPATSSQPT---LTFSNTSTPTFNIP 686
            +TT +   PT  PT T + +    +   +   T  P  +  PT   +T + T TPT   P
Sbjct: 2775 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-PTP 2833

Query: 687  FGSS--AKSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAP 744
             G+     +P+ +     P P        P G   P  TP      T   +  P P    
Sbjct: 2834 TGTQTPTTTPITTTTTVTPTPT-------PTGTQTPTTTP-----ITTTTTVTPTPTPTG 2881

Query: 745  TPAPASTIKIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFG 804
            T  P +T  I      TP     G  T +   +  T +    P  +      +T + +  
Sbjct: 2882 TQTPTTT-PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2940

Query: 805  AATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATTGA 864
              T +     TQT ++ +  +   + TP+P T  G+  P  +        TP  + T   
Sbjct: 2941 TVTPTPTPTGTQTPTT-TPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT--- 2995

Query: 865  FSFGAGQSGSTATSTPFTGGLGQNALGT-TGQSTPFAFNVGSTTESKPVFGGTATPTFGQ 923
                      T T+TP T         T TG  TP    + +TT   P    T TPT G 
Sbjct: 2996 -------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP----TPTPT-GT 3043

Query: 924  NTP 926
             TP
Sbjct: 3044 QTP 3046



 Score =  132 bits (331), Expect = 2e-30
 Identities = 162/663 (24%), Positives = 241/663 (36%), Gaps = 89/663 (13%)

Query: 298  TETPPTTQPSFTFTLPAAATASP---PTSLLAPSTNPLLESLKKMQTP-PSLPPCPESAG 353
            T TP  TQ   T  +    T +P   PT    P+T P+  +     TP P+    P +  
Sbjct: 2761 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2820

Query: 354  AATTEALSPPKTPS-----LLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPA 408
              TT  ++P  TP+        P+  + +  P   P+P+    P TT     P  +    
Sbjct: 2821 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGTQTPTTT-----PITTTTTV 2873

Query: 409  TDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQN--------TSPSSPAAPAASSAS 460
            T T  P   Q  T T    T+  +P P  +   GTQ         T+  +P      + +
Sbjct: 2874 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQT 2930

Query: 461  PMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSSSL-----PTTTSTTAPTFQPVFSSMGP 515
            P   PI T    +    PTP G     T P +++      PT T T  PT  P+ ++   
Sbjct: 2931 PTTTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-- 2986

Query: 516  PASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGI 575
                P P P    T TP T P TT    T   + T    P T+   +T + +      G 
Sbjct: 2987 -TVTPTPTP--TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3043

Query: 576  NSVSSSSVSTTTS-----TATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTT 630
             + +++ ++TTT+     T T    P        +  + TP              PTTT 
Sbjct: 3044 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-------TQTPTTTP 3096

Query: 631  VTTFSQSLPTAVPTATSS-SAADFSGFGSTLATSAPATSSQPT---LTFSNTSTPTFNIP 686
            +TT +   PT  PT T + +    +   +   T  P  +  PT   +T + T TPT   P
Sbjct: 3097 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-PTP 3155

Query: 687  FGSS--AKSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAP 744
             G+     +P+ +     P P        P G   P  TP      T   +  P P    
Sbjct: 3156 TGTQTPTTTPITTTTTVTPTPT-------PTGTQTPTTTP-----ITTTTTVTPTPTPTG 3203

Query: 745  TPAPASTIKIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFG 804
            T  P +T  I      TP     G  T +   +  T +    P  +      +T + +  
Sbjct: 3204 TQTPTTT-PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3262

Query: 805  AATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATTGA 864
              T +     TQT ++ +  +   + TP+P T  G+  P  +        TP  + T   
Sbjct: 3263 TVTPTPTPTGTQTPTT-TPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT--- 3317

Query: 865  FSFGAGQSGSTATSTPFTGGLGQNALGT-TGQSTPFAFNVGSTTESKPVFGGTATPTFGQ 923
                      T T+TP T         T TG  TP    + +TT   P    T TPT G 
Sbjct: 3318 -------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP----TPTPT-GT 3365

Query: 924  NTP 926
             TP
Sbjct: 3366 QTP 3368



 Score =  132 bits (331), Expect = 2e-30
 Identities = 162/663 (24%), Positives = 241/663 (36%), Gaps = 89/663 (13%)

Query: 298  TETPPTTQPSFTFTLPAAATASP---PTSLLAPSTNPLLESLKKMQTP-PSLPPCPESAG 353
            T TP  TQ   T  +    T +P   PT    P+T P+  +     TP P+    P +  
Sbjct: 3083 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3142

Query: 354  AATTEALSPPKTPS-----LLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPA 408
              TT  ++P  TP+        P+  + +  P   P+P+    P TT     P  +    
Sbjct: 3143 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGTQTPTTT-----PITTTTTV 3195

Query: 409  TDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQN--------TSPSSPAAPAASSAS 460
            T T  P   Q  T T    T+  +P P  +   GTQ         T+  +P      + +
Sbjct: 3196 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQT 3252

Query: 461  PMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSSSL-----PTTTSTTAPTFQPVFSSMGP 515
            P   PI T    +    PTP G     T P +++      PT T T  PT  P+ ++   
Sbjct: 3253 PTTTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-- 3308

Query: 516  PASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGI 575
                P P P    T TP T P TT    T   + T    P T+   +T + +      G 
Sbjct: 3309 -TVTPTPTP--TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3365

Query: 576  NSVSSSSVSTTTS-----TATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTT 630
             + +++ ++TTT+     T T    P        +  + TP              PTTT 
Sbjct: 3366 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-------TQTPTTTP 3418

Query: 631  VTTFSQSLPTAVPTATSS-SAADFSGFGSTLATSAPATSSQPT---LTFSNTSTPTFNIP 686
            +TT +   PT  PT T + +    +   +   T  P  +  PT   +T + T TPT   P
Sbjct: 3419 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-PTP 3477

Query: 687  FGSS--AKSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAP 744
             G+     +P+ +     P P        P G   P  TP      T   +  P P    
Sbjct: 3478 TGTQTPTTTPITTTTTVTPTPT-------PTGTQTPTTTP-----ITTTTTVTPTPTPTG 3525

Query: 745  TPAPASTIKIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFG 804
            T  P +T  I      TP     G  T +   +  T +    P  +      +T + +  
Sbjct: 3526 TQTPTTT-PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3584

Query: 805  AATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATTGA 864
              T +     TQT ++ +  +   + TP+P T  G+  P  +        TP  + T   
Sbjct: 3585 TVTPTPTPTGTQTPTT-TPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT--- 3639

Query: 865  FSFGAGQSGSTATSTPFTGGLGQNALGT-TGQSTPFAFNVGSTTESKPVFGGTATPTFGQ 923
                      T T+TP T         T TG  TP    + +TT   P    T TPT G 
Sbjct: 3640 -------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP----TPTPT-GT 3687

Query: 924  NTP 926
             TP
Sbjct: 3688 QTP 3690



 Score =  132 bits (331), Expect = 2e-30
 Identities = 162/663 (24%), Positives = 241/663 (36%), Gaps = 89/663 (13%)

Query: 298  TETPPTTQPSFTFTLPAAATASP---PTSLLAPSTNPLLESLKKMQTP-PSLPPCPESAG 353
            T TP  TQ   T  +    T +P   PT    P+T P+  +     TP P+    P +  
Sbjct: 3405 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3464

Query: 354  AATTEALSPPKTPS-----LLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPA 408
              TT  ++P  TP+        P+  + +  P   P+P+    P TT     P  +    
Sbjct: 3465 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGTQTPTTT-----PITTTTTV 3517

Query: 409  TDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQN--------TSPSSPAAPAASSAS 460
            T T  P   Q  T T    T+  +P P  +   GTQ         T+  +P      + +
Sbjct: 3518 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQT 3574

Query: 461  PMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSSSL-----PTTTSTTAPTFQPVFSSMGP 515
            P   PI T    +    PTP G     T P +++      PT T T  PT  P+ ++   
Sbjct: 3575 PTTTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-- 3630

Query: 516  PASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGI 575
                P P P    T TP T P TT    T   + T    P T+   +T + +      G 
Sbjct: 3631 -TVTPTPTP--TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3687

Query: 576  NSVSSSSVSTTTS-----TATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTT 630
             + +++ ++TTT+     T T    P        +  + TP              PTTT 
Sbjct: 3688 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-------TQTPTTTP 3740

Query: 631  VTTFSQSLPTAVPTATSS-SAADFSGFGSTLATSAPATSSQPT---LTFSNTSTPTFNIP 686
            +TT +   PT  PT T + +    +   +   T  P  +  PT   +T + T TPT   P
Sbjct: 3741 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-PTP 3799

Query: 687  FGSS--AKSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAP 744
             G+     +P+ +     P P        P G   P  TP      T   +  P P    
Sbjct: 3800 TGTQTPTTTPITTTTTVTPTPT-------PTGTQTPTTTP-----ITTTTTVTPTPTPTG 3847

Query: 745  TPAPASTIKIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFG 804
            T  P +T  I      TP     G  T +   +  T +    P  +      +T + +  
Sbjct: 3848 TQTPTTT-PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3906

Query: 805  AATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATTGA 864
              T +     TQT ++ +  +   + TP+P T  G+  P  +        TP  + T   
Sbjct: 3907 TVTPTPTPTGTQTPTT-TPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT--- 3961

Query: 865  FSFGAGQSGSTATSTPFTGGLGQNALGT-TGQSTPFAFNVGSTTESKPVFGGTATPTFGQ 923
                      T T+TP T         T TG  TP    + +TT   P    T TPT G 
Sbjct: 3962 -------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP----TPTPT-GT 4009

Query: 924  NTP 926
             TP
Sbjct: 4010 QTP 4012



 Score =  131 bits (329), Expect = 4e-30
 Identities = 153/619 (24%), Positives = 229/619 (36%), Gaps = 71/619 (11%)

Query: 298  TETPPTTQPSFTFTLPAAATASP---PTSLLAPSTNPLLESLKKMQTP-PSLPPCPESAG 353
            T TP  TQ   T  +    T +P   PT    P+T P+  +     TP P+    P +  
Sbjct: 3727 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3786

Query: 354  AATTEALSPPKTPS-----LLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPA 408
              TT  ++P  TP+        P+  + +  P   P+P+    P TT     P  +    
Sbjct: 3787 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGTQTPTTT-----PITTTTTV 3839

Query: 409  TDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQN--------TSPSSPAAPAASSAS 460
            T T  P   Q  T T    T+  +P P  +   GTQ         T+  +P      + +
Sbjct: 3840 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQT 3896

Query: 461  PMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSSSL-----PTTTSTTAPTFQPVFSSMGP 515
            P   PI T    +    PTP G     T P +++      PT T T  PT  P+ ++   
Sbjct: 3897 PTTTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-- 3952

Query: 516  PASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGI 575
                P P P    T TP T P TT    T   + T    P T+   +T + +      G 
Sbjct: 3953 -TVTPTPTP--TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 4009

Query: 576  NSVSSSSVSTTTS-----TATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTT 630
             + +++ ++TTT+     T T    P        +  + TP              PTTT 
Sbjct: 4010 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-------TQTPTTTP 4062

Query: 631  VTTFSQSLPTAVPTATSS-SAADFSGFGSTLATSAPATSSQPT---LTFSNTSTPTFNIP 686
            +TT +   PT  PT T + +    +   +   T  P  +  PT   +T + T TPT   P
Sbjct: 4063 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-PTP 4121

Query: 687  FGSS--AKSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAP 744
             G+     +P+ +     P P        P G   P  TP   ++ T   +  P     P
Sbjct: 4122 TGTQTPTTTPITTTTTVTPTPT-------PTGTQTPTTTP-ITTTTTVTPTPTPTGTQTP 4173

Query: 745  TPAPASTIKIVPAHVPTPIQPTFGGATH-SAFGLKATASAFGAPASSQPAFGGSTAVFSF 803
            T  P +T   V    PTP     G  TH S   +    ++   P SS P    ST   S 
Sbjct: 4174 TTTPITTTTTV-TPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRST---SS 4229

Query: 804  GAATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATTG 863
                S+   +T   A   +S++   + T    T GG        +      TP    TTG
Sbjct: 4230 PLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTG 4289

Query: 864  AFSFGAGQSGSTATSTPFT 882
            + S     +  T T++ +T
Sbjct: 4290 SSSAPTPSTVQTTTTSAWT 4308



 Score =  127 bits (319), Expect = 5e-29
 Identities = 163/666 (24%), Positives = 240/666 (36%), Gaps = 95/666 (14%)

Query: 298  TETPPTTQPSFTFTLPAAATASP---PTSLLAPSTNPLLESLKKMQTP-PSLPPCPESAG 353
            T TP  TQ   T  +    T +P   PT    P+T P+  +     TP P+    P +  
Sbjct: 1956 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2015

Query: 354  AATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVP------ 407
              TT  ++P  TP+         +  P   P  +  +  PT        P+  P      
Sbjct: 2016 ITTTTTVTPTPTPT--------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2067

Query: 408  ATDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQ--------NTSPSSPAAPAASSA 459
             T T  P   Q  T T    T+  +P P  +   GTQ         T+  +P      + 
Sbjct: 2068 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQ 2124

Query: 460  SPMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSSS-----LPTTTSTTAPTFQPVFSSMG 514
            +P   PI T    +    PTP G     T P +++      PT T T  PT  P+ ++  
Sbjct: 2125 TPTTTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT-- 2180

Query: 515  PPASVPLPAPFFKQ--TTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFG 572
                 P P P   Q  TTTP T  TT  P  T   + T    PIT+ +  T + +     
Sbjct: 2181 -TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT--- 2236

Query: 573  FGINSVSSSSVSTTTS-----TATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPT 627
             G  + +++ ++TTT+     T T    P        +  + TP              PT
Sbjct: 2237 -GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-------TQTPT 2288

Query: 628  TTTVTTFSQSLPTAVPTATSS-SAADFSGFGSTLATSAPATSSQPT---LTFSNTSTPTF 683
            TT +TT +   PT  PT T + +    +   +   T  P  +  PT   +T + T TPT 
Sbjct: 2289 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT- 2347

Query: 684  NIPFGSS--AKSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPA 741
              P G+     +P+ +     P P        P G   P  TP      T   +  P P 
Sbjct: 2348 PTPTGTQTPTTTPITTTTTVTPTPT-------PTGTQTPTTTP-----ITTTTTVTPTPT 2395

Query: 742  TAPTPAPASTIKIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVF 801
               T  P +T  I      TP     G  T +   +  T +    P  +      +T + 
Sbjct: 2396 PTGTQTPTTT-PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2454

Query: 802  SFGAATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSAT 861
            +    T +     TQT ++ +  +   + TP+P T  G+  P  +        TP  + T
Sbjct: 2455 TTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT 2512

Query: 862  TGAFSFGAGQSGSTATSTPFTGGLGQNALGT-TGQSTPFAFNVGSTTESKPVFGGTATPT 920
                         T T+TP T         T TG  TP    + +TT   P    T TPT
Sbjct: 2513 ----------GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP----TPTPT 2558

Query: 921  FGQNTP 926
             G  TP
Sbjct: 2559 -GTQTP 2563



 Score =  121 bits (304), Expect = 3e-27
 Identities = 121/435 (27%), Positives = 176/435 (40%), Gaps = 52/435 (11%)

Query: 336  LKKMQTPPSLPPCPESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLPSP---SFDSKP 392
            + K  T PS P    S    +T  L P  TPS  PP   + + PP   PSP   +  + P
Sbjct: 1392 MDKCITTPSPPTTTPSPPPTSTTTLPPTTTPS--PPTTTTTTPPPTTTPSPPITTTTTPP 1449

Query: 393  PTTLLGLIPAPSMVPATDTKAPPTL--QAETATKPQATSAPSPAPKQSFLFGTQNTSPSS 450
            PTT       PS   +T T  PPT      T T    T+ PSP         T  T+P  
Sbjct: 1450 PTT------TPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPT-------TTTTTPPP 1496

Query: 451  PAAPAASSASPMFKPIFTA--PPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQP 508
               P+  + +P+  P  T   PP +     TP  P+ T T P  ++ P+  +TT P   P
Sbjct: 1497 TTTPSPPTTTPITPPASTTTLPPTT-----TPSPPTTTTTTPPPTTTPSPPTTT-PITPP 1550

Query: 509  VFSSMGPPASVPLPAPFFKQTTTPATA---PTTTAPLFTGLASATSAVAPITSASPSTDS 565
              ++  PP + P P P    T  P T    PTTT P  +     T+   P T+ SP T +
Sbjct: 1551 TSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTP--SPPTITTTTPPPTTTPSPPTTT 1608

Query: 566  ASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPAL 625
             + P      +  +++ ++  TST T    P    +P  +  +  P   +       P+ 
Sbjct: 1609 TTTPPPTTTPSPPTTTPITPPTSTTTL--PPTTTPSPPPTTTTTPPPTTT-------PSP 1659

Query: 626  PTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNI 685
            PTTTT +    +  T  PT T SS    +    T   + P+ ++ P+   + T+TP+   
Sbjct: 1660 PTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPS--- 1716

Query: 686  PFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAPT 745
               ++  SP P+     P P        PP      L P+  SS     +  P   T PT
Sbjct: 1717 --STTTPSPPPT-TMTTPSP---TTTPSPPTTTMTTLPPTTTSS-PLTTTPLPPSITPPT 1769

Query: 746  PAPASTIKIVPAHVP 760
             +P ST       VP
Sbjct: 1770 FSPFSTTTPTTPCVP 1784



 Score =  111 bits (278), Expect = 3e-24
 Identities = 144/590 (24%), Positives = 215/590 (36%), Gaps = 81/590 (13%)

Query: 349  PESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPA 408
            P +    TTE  +PP T     P+  + +  P   P+P+    P TT     P  +    
Sbjct: 1882 PTTMTTTTTENPTPPTTT----PITTTTTVTP--TPTPTGTQTPTTT-----PITTTTTV 1930

Query: 409  TDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFT 468
            T T  P   Q  T T    T+  +P P  +   GTQ  +P++      ++ +P   P  T
Sbjct: 1931 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT---GTQ--TPTTTPITTTTTVTPTPTPTGT 1985

Query: 469  APPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQ 528
              P       T P  + T   P+    PT T T  PT  P+ ++       P P P    
Sbjct: 1986 QTPT------TTPITTTTTVTPT----PTPTGTQTPTTTPITTTT---TVTPTPTP--TG 2030

Query: 529  TTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTS 588
            T TP T P TT    T   + T    P T+   +T + +      G  + +++ ++TTT+
Sbjct: 2031 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2090

Query: 589  -----TATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVP 643
                 T T    P        +  + TP              PTTT +TT +   PT  P
Sbjct: 2091 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-------TQTPTTTPITTTTTVTPTPTP 2143

Query: 644  TATSS-SAADFSGFGSTLATSAPATSSQPT---LTFSNTSTPTFNIPFGSS--AKSPLPS 697
            T T + +    +   +   T  P  +  PT   +T + T TPT   P G+     +P+ +
Sbjct: 2144 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITT 2202

Query: 698  YPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVPA 757
                 P P        P G   P  TP      T   +  P P    T  P +T  I   
Sbjct: 2203 TTTVTPTPT-------PTGTQTPTTTP-----ITTTTTVTPTPTPTGTQTPTTT-PITTT 2249

Query: 758  HVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAATSSGFGATTQT 817
               TP     G  T +   +  T +    P  +      +T + +    T +     TQT
Sbjct: 2250 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2309

Query: 818  ASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATTGAFSFGAGQSGSTAT 877
             ++ +  +   + TP+P T  G+  P  +        TP  + T             T T
Sbjct: 2310 PTT-TPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPT----------GTQTPT 2357

Query: 878  STPFTGGLGQNALGT-TGQSTPFAFNVGSTTESKPVFGGTATPTFGQNTP 926
            +TP T         T TG  TP    + +TT   P    T TPT G  TP
Sbjct: 2358 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP----TPTPT-GTQTP 2402



 Score =  107 bits (266), Expect = 7e-23
 Identities = 117/438 (26%), Positives = 169/438 (38%), Gaps = 65/438 (14%)

Query: 298  TETPPTTQPSFTFTLPAAATASP---PTSLLAPSTNPLLESLKKMQTP-PSLPPCPESAG 353
            T TP  TQ   T  +    T +P   PT    P+T P+  +     TP P+    P +  
Sbjct: 3911 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3970

Query: 354  AATTEALSPPKTPS-----LLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPA 408
              TT  ++P  TP+        P+  + +  P   P+P+    P TT     P  +    
Sbjct: 3971 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGTQTPTTT-----PITTTTTV 4023

Query: 409  TDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQN--------TSPSSPAAPAASSAS 460
            T T  P   Q  T T    T+  +P P  +   GTQ         T+  +P      + +
Sbjct: 4024 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQT 4080

Query: 461  PMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSSSL-----PTTTSTTAPTFQPVFSSMGP 515
            P   PI T    +    PTP G     T P +++      PT T T  PT  P+ ++   
Sbjct: 4081 PTTTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-- 4136

Query: 516  PASVPLPAPFFKQT--TTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGF 573
                P P P   QT  TTP T  TT  P  T   + T    PIT+ +  T + +      
Sbjct: 4137 -TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG--- 4192

Query: 574  GINSVSSSSVSTTTSTA-----TAASQPFLFGAPQASAASFTPAMGSIFQFGK-PPALPT 627
                 + +   T TSTA     T ++ P     PQ S ++ +P   S       PPA+  
Sbjct: 4193 -----TQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEM 4247

Query: 628  TTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPF 687
            T+T      S PTA PT TS         G TL+     T+S P      T+T + + P 
Sbjct: 4248 TSTAPP---STPTA-PTTTSG--------GHTLSPPPSTTTSPPGTPTRGTTTGSSSAPT 4295

Query: 688  GSSAKSPLPSYPGANPQP 705
             S+ ++   S     P P
Sbjct: 4296 PSTVQTTTTSAWTPTPTP 4313



 Score = 99.8 bits (247), Expect = 1e-20
 Identities = 126/512 (24%), Positives = 178/512 (34%), Gaps = 58/512 (11%)

Query: 384  PSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGT 443
            PS   D     T  G+  AP  +     K P     +   K Q   +     K    FG 
Sbjct: 1314 PSSGSDDGDRETFDGVCGAPEDIECRSVKDPHLSLEQLGQKVQCDVSVGFICKNEDQFGN 1373

Query: 444  QNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTA 503
                         +   PM K I T  P +    P+PP  S T   P+++  P TT+TT 
Sbjct: 1374 GPFGLCYDYKIRVNCCWPMDKCITTPSPPTTT--PSPPPTSTTTLPPTTTPSPPTTTTTT 1431

Query: 504  PTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPST 563
            P          PP + P P      T  P T P+      T     T+   P T+ SP T
Sbjct: 1432 P----------PPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPT 1481

Query: 564  DSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPP 623
             + S P              +TTT+T    + P    +P  +     PA  +       P
Sbjct: 1482 TTPSPP--------------TTTTTTPPPTTTP----SPPTTTPITPPASTTTLPPTTTP 1523

Query: 624  ALPTTTTVT---TFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTST 680
            + PTTTT T   T + S PT  P    +S        +T  +  P T++ P  T +  S 
Sbjct: 1524 SPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLP--PTTTPSPPPTTTTTPPPT-TTPSP 1580

Query: 681  PTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGA--AKPALTPSFGSSFTFGNSAAP 738
            PT   P   +  +  P  P   P P        PP    + P  TP    + T       
Sbjct: 1581 PTTTTPSPPTITTTTPP-PTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTST----TTL 1635

Query: 739  APATAPTPAPASTIKIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGST 798
             P T P+P P +T    P   P+P   T      +        +   +P ++ P+   +T
Sbjct: 1636 PPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTT 1695

Query: 799  AVFSFGAATSSGFGATTQTASSGSSSS--------VFGSTTPSPFTFGGSAAPAGSGSFG 850
                    T S    TT T SS ++ S           +TTPSP T   +  P  + S  
Sbjct: 1696 MTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSP 1755

Query: 851  INVATPGSSATTGAFSFGAGQSGSTATSTPFT 882
            +       S T   FS         +T+TP T
Sbjct: 1756 LTTTPLPPSITPPTFS-------PFSTTTPTT 1780



 Score = 96.3 bits (238), Expect = 1e-19
 Identities = 131/519 (25%), Positives = 189/519 (36%), Gaps = 93/519 (17%)

Query: 298  TETPPTTQPSFTFTLPAAATASP---PTSLLAPSTNPLLESLKKMQTP-PSLPPCPESAG 353
            T TP  TQ   T  +    T +P   PT    P+T P+  +     TP P+    P +  
Sbjct: 3980 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4039

Query: 354  AATTEALSPPKTPS-----LLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPA 408
              TT  ++P  TP+        P+  + +  P   P+P+    P TT     P  +    
Sbjct: 4040 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGTQTPTTT-----PITTTTTV 4092

Query: 409  TDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFT 468
            T T  P   Q  T T    T+  +P P  +   GTQ  +P++      ++ +P   P  T
Sbjct: 4093 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT---GTQ--TPTTTPITTTTTVTPTPTPTGT 4147

Query: 469  APPKSEKEGPTP---PGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPF 525
              P +     T    P P+ T T   +++  TTT+T  PT  P  +  GPP      AP 
Sbjct: 4148 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTST-API 4206

Query: 526  FKQTT--------TPATAPTTTAPLF---TGLASATSAVAPITSASPSTDSASKPAFGFG 574
             + TT        TP T+ +T++PL    T L++   A+   ++A PST +A     G  
Sbjct: 4207 AELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSG-- 4264

Query: 575  INSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTF 634
                 S   STTTS                     TP  G+       P  P+T   TT 
Sbjct: 4265 -GHTLSPPPSTTTSPPG------------------TPTRGTTTGSSSAPT-PSTVQTTTT 4304

Query: 635  SQSLPTAVPTATSS--SAADFSGFGSTLATS--------APA----------------TS 668
            S   PT  P +T S         + S++           AP                  S
Sbjct: 4305 SAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCS 4364

Query: 669  SQPTLTFSNTSTPTFNIPFGSSAKS-PLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFG 727
               TL F N S P+   P  + +KS P PS P + P         +P    KP   P F 
Sbjct: 4365 LSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTP--------SKPTPGTKPPECPDFD 4416

Query: 728  SSFTFGNSAAPAPATAPTPAPASTIKIVPAHVPTPIQPT 766
                   +         T    +T++IV      P  PT
Sbjct: 4417 PPRQENETWWLCDCFMATCKYNNTVEIVKVECEPPPMPT 4455



 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 80/314 (25%), Positives = 113/314 (35%), Gaps = 27/314 (8%)

Query: 622  PPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTP 681
            PP   TTT   T + S PT   T    +        +T  T  P T+  P ++ + T  P
Sbjct: 1408 PPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPI-TTTTTPPPTTTPSPPISTTTTPPP 1466

Query: 682  TFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGA--AKPALTPSFGSSFTFGNSAAPA 739
            T       S  +  PS P   P P        PP    + P  TP      T   S    
Sbjct: 1467 TTT----PSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTP-----ITPPASTTTL 1517

Query: 740  PATAPTPAPASTIKIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTA 799
            P T  TP+P +T    P    TP  PT    T          S    P ++ P+   +T 
Sbjct: 1518 PPTT-TPSPPTTTTTTPPPTTTPSPPTTTPIT-------PPTSTTTLPPTTTPSPPPTTT 1569

Query: 800  VFSFGAATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVA--TPG 857
                   T S    TT +  + ++++   +TTPSP T   +  P  +          TP 
Sbjct: 1570 TTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPP 1629

Query: 858  SSATTGAFSFGAGQSGSTATSTPFTGGLGQNALGTTGQSTPFAFNVG---STTESKPVFG 914
            +S TT   +       +T T+ P T     +   TT  S P         +TT S P+  
Sbjct: 1630 TSTTTLPPTTTPSPPPTTTTTPPPT--TTPSPPTTTTPSPPITTTTTPPPTTTPSSPITT 1687

Query: 915  GTATPTFGQNTPAP 928
              + PT    TP+P
Sbjct: 1688 TPSPPTTTMTTPSP 1701



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 74/366 (20%), Positives = 130/366 (35%), Gaps = 40/366 (10%)

Query: 126  SSSMSSLTGAYTSGIPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRSQTPER 185
            ++ +++ T    +  P+ ++   T+  ++T  ++      G + +P ++P ++ +     
Sbjct: 4083 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG-TQTPTTTPITTTTTVTPT 4141

Query: 186  PAKKIREEELCHHSSSSTPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQRKRKVQL 245
            P     +       +++T +       G +   TTP     + + +   +  Q       
Sbjct: 4142 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHT 4201

Query: 246  LPSRRGEQLTLPPPPQLGYSITAEDLD---LEKKASLQWFNQALEDKSDAASNSVTETPP 302
              +   E  T  PPP+     T+        E    L     A+E  S A  ++ T  P 
Sbjct: 4202 STAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPT-APT 4260

Query: 303  TTQPSFTFTLPAAATASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALSP 362
            TT    T + P + T SPP +    +T           T  S  P P +    TT A +P
Sbjct: 4261 TTSGGHTLSPPPSTTTSPPGTPTRGTT-----------TGSSSAPTPSTVQTTTTSAWTP 4309

Query: 363  P----KTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPAT--------D 410
                  TPS++   GL       L+     D+          P   +   T        +
Sbjct: 4310 TPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTY-------YAPGEEVYNGTYGDTCYFVN 4362

Query: 411  TKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAP 470
                 TL+    + P   S PSP P  S    T +   S+P+ P   +  P   P F  P
Sbjct: 4363 CSLSCTLEFYNWSCP---STPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPEC-PDFD-P 4417

Query: 471  PKSEKE 476
            P+ E E
Sbjct: 4418 PRQENE 4423


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score =  124 bits (310), Expect = 6e-28
 Identities = 209/807 (25%), Positives = 278/807 (34%), Gaps = 121/807 (14%)

Query: 4    SPVTVRIAPPDRR---FSRSAIPEQIISSTLSSPSSNAPDPCAKETVLSALKEKKKKRTV 60
            SP+ V ++P  +R      SA P+  I + LSSP S        E  LS    K    T 
Sbjct: 795  SPLGVSVSPQTKRPPTKKGSAGPDTPIGN-LSSPVSPVEASFLPENSLSFQGSKDSPATT 853

Query: 61   EEEDQIFLDGQENKRRRHDSSGSGHSAFEPLVASGV--PASFVPKPGSLKRGLNSQSSDD 118
                     G               SA  PL   GV  P    P P  +      +    
Sbjct: 854  HSPTPPSPKGAPTP-----------SAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPAT 902

Query: 119  HLNKRSRSSSMSSLTGAYTSGIPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASS 178
               K++ + SM       TS  P  +R     +  + +GI       G  + P ++P S 
Sbjct: 903  PAPKQAPALSM-------TSSSPKKAR-----ATPAPKGIPASPSPKGAPTPPAATPPSP 950

Query: 179  RSQTPERPAKKIREEELCHHSSSSTPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQ 238
            +   P  P+ K           + TP AA   S   K    TP  K    + + P ++  
Sbjct: 951  KGG-PATPSPKW----------APTPPAATPPSP--KGGPATPSPK---GAPTPPAATPP 994

Query: 239  RKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVT 298
              +     PS +G     P PP    ++T        K S      A       AS    
Sbjct: 995  SPKGGPATPSPKGA----PTPP----AVTPPS----PKGS-----PAATPFPKGASTPPA 1037

Query: 299  ETPPTTQPSFTFT-LPAAATASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATT 357
             TPP+ + S   T LP  A  +P  +L +P   P   SLK   TPP+  P     G AT 
Sbjct: 1038 ATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATP 1097

Query: 358  EALSPPKTPSLLPPL---GLSQSGPPGLLPSPSFDSKPPTTLLGL-IPAPSMVPATDTKA 413
                 P  P+  PP    GL+     G   +P+  + PP+   GL  P P   P T    
Sbjct: 1098 SPKGAPMPPAATPPSPKGGLATPPHKGAPTTPA--ATPPSPKGGLATPPPKGAPTTPAAT 1155

Query: 414  PPTLQAETAT-----KPQATSAPSPAPKQSFLFGTQNTSP-SSPAAPAASSASPMFKPIF 467
            PP+ +   AT      P   +A  P+PK     G    SP  +P  PAA+  SP    + 
Sbjct: 1156 PPSPKGGLATPPPKGAPTTPAATPPSPKG----GLATPSPKGAPTTPAATPPSPK-GGLA 1210

Query: 468  TAPPKSEKEGP--TPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPF 525
            T  PK     P  TPP P      PS    PTT + T P      S  G PA+   P P 
Sbjct: 1211 TPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP------SPKGGPAT---PPPK 1261

Query: 526  FKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVST 585
               T   AT P+    L T         A +T  SP    A+ P  G           + 
Sbjct: 1262 GAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKG-----------AP 1310

Query: 586  TTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTA 645
            T   AT  S     G P    A   PA+        PP+   T T       LP   P++
Sbjct: 1311 TPPAATPPSPKGSPGTPPPKGAPTPPAV-------TPPSPKGTPT-------LPATTPSS 1356

Query: 646  TSSSAADFSGFGSTLATSAPATSSQPTLT-FSNTSTPTFNIPFG---SSAKSPL-PSYPG 700
                    S  G T   + P+    P +T  S    P    P G   S A  PL P    
Sbjct: 1357 KGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAP 1416

Query: 701  ANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVPAHVP 760
            A P    GAA         PA+TP         ++    PAT  +    +   + P    
Sbjct: 1417 ATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPK 1476

Query: 761  TPIQPTFGGATHSAFGLKATASAFGAP 787
             P  P     + S     AT +  GAP
Sbjct: 1477 EPPAPKQVATSSSPKKAPATPAPMGAP 1503



 Score =  115 bits (288), Expect = 2e-25
 Identities = 217/847 (25%), Positives = 288/847 (34%), Gaps = 143/847 (16%)

Query: 167  PSSSPFSSPASSRSQTPERPAKKIREEELCHHSSSSTPLAADKESQGEKAADTTPRKKQN 226
            P +SP     SS  + P  P   + ++ L        P+     S        +      
Sbjct: 567  PKNSPSFQSTSSSPEIPLSPEATLAKKSL----GEPLPIGKPASSMTSPLGVNSSASVIK 622

Query: 227  SNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLG---------YSITAEDLDLEKKA 277
            ++S + P S+G   +   + P+     L    P  +          Y+ TA    LE   
Sbjct: 623  TDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPF-LEGTV 681

Query: 278  SLQWFNQALEDKSDAASNSVTETPPTTQPSFTFTLPAAATASPPTSLLAP-STNPLLESL 336
            SL   N           + V E   TT P           A  P +  AP +T  L   +
Sbjct: 682  SLAPKN-----------HPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEI 730

Query: 337  KKMQTPPSLPPCPESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTL 396
             K    PSLPP     G    + +S     S L P+  S    P      S  +    TL
Sbjct: 731  PKSVPSPSLPPAGTPPGTKKVDGIS---HTSALAPVASSPKECPTEDSGASATASSKGTL 787

Query: 397  LGLIPAPSMVPAT---DTKAPPTLQAETATKPQATSAPSPA--------PKQSFLF-GTQ 444
              L  +PS +  +    TK PPT +          +  SP         P+ S  F G++
Sbjct: 788  TYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSK 847

Query: 445  N--------TSPSSPAAPAASSASPMFKPIFTAPPKS-----------EKEGPTPPGP-S 484
            +        T PS   AP  S+ +P+     T PPK             KEGP  P P  
Sbjct: 848  DSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQ 907

Query: 485  VTATAPSSSSLPTTTSTTAPTFQPVFSS----MGPPASVP--------LPAPFFKQTTTP 532
              A + +SSS     +T AP   P   S      PPA+ P         P+P +  T   
Sbjct: 908  APALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPA 967

Query: 533  ATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATA 592
            AT P+       G A+ +   AP   A+        PA      + +  +V+  +   + 
Sbjct: 968  ATPPSPKG----GPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSP 1023

Query: 593  ASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAAD 652
            A+ PF  GA    AA+     GS      P   PTT   T  S     A P+   +    
Sbjct: 1024 AATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPP 1083

Query: 653  FSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSP---LPSYPGAN-PQPAFG 708
             +   S      PAT S         +TP    P G  A  P    P+ P A  P P  G
Sbjct: 1084 AATPPS--PKGGPATPSPKGAPMPPAATPP--SPKGGLATPPHKGAPTTPAATPPSPKGG 1139

Query: 709  AAEGQPPGA-AKPALTPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVPAHVPTPIQPTF 767
             A   P GA   PA TP        G  A P P  APT   A           TP  P  
Sbjct: 1140 LATPPPKGAPTTPAATPPSPK----GGLATPPPKGAPTTPAA-----------TPPSPKG 1184

Query: 768  GGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSVF 827
            G AT S  G   T      PA++ P+  G       G AT S  GA T  A         
Sbjct: 1185 GLATPSPKGAPTT------PAATPPSPKG-------GLATPSPKGAPTTPA--------- 1222

Query: 828  GSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATTGAFSFGAGQSGSTATSTPFTGGLGQ 887
             +T PSP   GG A P+  G+     ATP S     A     G     A + P   G   
Sbjct: 1223 -ATPPSP--KGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKG--- 1276

Query: 888  NALGTTGQSTP---FAFNVGSTTESKPVFGGTATPTFGQNTPAPGV-----GTSGSSLSF 939
                  G +TP    A N    T   P  G   +P  G  TP         G+ G+    
Sbjct: 1277 ------GLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPK 1330

Query: 940  GASSAPA 946
            GA + PA
Sbjct: 1331 GAPTPPA 1337



 Score =  114 bits (284), Expect = 6e-25
 Identities = 207/768 (26%), Positives = 275/768 (35%), Gaps = 103/768 (13%)

Query: 290  SDAASNSVTETPPTTQPSFTFTLPAAATASPPTSLLAPSTNPLLESLKKMQTPPSLPPCP 349
            S  AS+  T T     PS      +  T  PPT   +   +  + +L    +P      P
Sbjct: 778  SATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLP 837

Query: 350  ESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLP-SPSFDSKP----PTTLLGLIPAPS 404
            E++ +      SP  T S  PP       P  + P SP   + P    PT  +  +P P 
Sbjct: 838  ENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPK 897

Query: 405  MVPATDT-KAPPTLQAETAT--KPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASP 461
              PAT   K  P L   +++  K +AT AP   P      G      ++P +P    A+P
Sbjct: 898  EGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATP 957

Query: 462  MFKPIFTAP---PKSEKEGPTPPGPS-----VTATAPSSSSLPTTTSTTAPTFQPVFSSM 513
              K   T P   P S K GP  P P        AT PS    P T S       P  +  
Sbjct: 958  SPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPP 1017

Query: 514  GPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGF 573
             P  S P   PF K  +TP   P  T P   G  +AT    P+   +P+T +A+ P+   
Sbjct: 1018 SPKGS-PAATPFPKGASTP---PAATPPSPKGSPAAT----PLPKGAPTTPAATLPSPKG 1069

Query: 574  G-----INSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPP--ALP 626
            G     +    +   +T  S     + P   GAP   AA+     G +     PP    P
Sbjct: 1070 GPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGL---ATPPHKGAP 1126

Query: 627  TTTTVTTFSQSLPTAVPT---ATSSSAADFSGFGSTLATSAP--------ATSSQPTLTF 675
            TT   T  S     A P    A ++ AA        LAT  P        AT   P    
Sbjct: 1127 TTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGL 1186

Query: 676  SNTS------TPTFNIPF---GSSAKSP--LPSYPGAN-PQPAFGAAEGQPPGA-AKPAL 722
            +  S      TP    P    G +  SP   P+ P A  P P  G A   P GA   PA 
Sbjct: 1187 ATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAA 1246

Query: 723  TPSFGSSFTFGNSAAPAPATAPTPAPASTIKI-----VPAH-------VPTPIQPTFGGA 770
            TP        G  A P P  APTP  A+   +      P H       V TP  P  G A
Sbjct: 1247 TPPSPK----GGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPA 1302

Query: 771  THSAFGLKATASAF-----GAPASSQPAFGGST--AVFSFGAATSSGFGATTQTASSG-- 821
            T    G     +A      G+P +  P  G  T  AV       +    ATT ++  G  
Sbjct: 1303 TSPPKGAPTPPAATPPSPKGSPGTPPPK-GAPTPPAVTPPSPKGTPTLPATTPSSKGGPT 1361

Query: 822  SSSSVFGSTTP--SPFTFGGSAAPAGSGSFGINVATPGSSATTGAFSFGAGQSGSTATST 879
            + SS  G T P  +P   GG A    S   G  + +P    T+ A       S   A +T
Sbjct: 1362 TPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAV---IPLSPKKAPAT 1418

Query: 880  PFT-GGLGQNALG--TTGQSTPFAFNVGSTTESKPVFGGTATPTFGQNTPAPGVGTSG-- 934
            P T  G    + G  T    TP +      T +    GG ATP+   +   P V      
Sbjct: 1419 PVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPK--GGPATPSSKGDPTLPAVTPPSPK 1476

Query: 935  ---SSLSFGASSAPAQGFVGVGPFGSAAPSFSIGAGSK----TPGARQ 975
               +      SS+P +      P G+      I +  K    TP +R+
Sbjct: 1477 EPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRR 1524



 Score = 99.8 bits (247), Expect = 1e-20
 Identities = 165/656 (25%), Positives = 231/656 (35%), Gaps = 125/656 (19%)

Query: 164  RNGPSSSPFSSPASSRSQTPERPAKKIREEELCHHSSSSTPLAADKESQGEKAADTTPRK 223
            + GP++SP     +  + TP  P              + TP A    S   K   T P  
Sbjct: 1298 KGGPATSPPKGAPTPPAATPPSPKGSPGTPP---PKGAPTPPAVTPPSP--KGTPTLPAT 1352

Query: 224  KQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFN 283
              +S    T  SS +        PS +G     PP P+ G +I +               
Sbjct: 1353 TPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSP-------------- 1398

Query: 284  QALEDKSDAASNSVTETPPTTQPSFTFTLPAAATASPPTSLLAPSTNPLLESLKKM---Q 340
                 K D  S +V    P   P+   T   AAT S    L  P+  P+  SLKK     
Sbjct: 1399 -----KGDPTSPAVIPLSPKKAPATPVTREGAATPSKG-DLTPPAVTPV--SLKKAPATS 1450

Query: 341  TPPSLPPCPESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLI 400
             P   P  P S G  T  A++PP       P  ++ S  P   P+       PT    + 
Sbjct: 1451 APKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIP 1510

Query: 401  PAPSMVPATDT---------------KAPPTLQAETATKPQATSAPSPAPKQSFLFGTQN 445
             +P  VPAT +               K P TL  + A  P A + PS  PK++    T  
Sbjct: 1511 SSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPS--PKKTPAIPTPK 1568

Query: 446  TSPSSPAAPAASS------------ASP---MFKPIFTAP------------PKSEKEGP 478
             +P++P++  ASS             SP   +  P  T+P            P S ++GP
Sbjct: 1569 EAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGP 1628

Query: 479  TPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMG---PPASVPLPA----PFFKQ--- 528
              P P  T T+P  +      S T+P    V   MG   P AS  LPA       K+   
Sbjct: 1629 ATPAPKGTPTSPPVTPSSLKDSPTSPA--SVTCKMGATVPQASKGLPAKKGPTALKEVLV 1686

Query: 529  TTTPATAPTTTAPLFTG-LASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSV---- 583
               P + P  TAP   G     +SA +P     PS  + SK      +++V+ + +    
Sbjct: 1687 APAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGP----LSTVAPAPLLPVQ 1742

Query: 584  ---STTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPT 640
               S T     A+  P    AP  S AS TP   + F+   P   P + +V+  + S P 
Sbjct: 1743 KDSSKTAKGKDASHSPKGPLAPPESKAS-TPLTAAAFEKVLPK--PESASVSA-APSPPV 1798

Query: 641  AVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPG 700
            ++P A S           TL        S P L   + S P       +     LP  P 
Sbjct: 1799 SLPLAPSPV--------PTLPPKQQFLPSSPGLVLESPSKPL----APADEDELLPLIP- 1845

Query: 701  ANPQPAFGAAEGQ--------PPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAP 748
              P+P  G    Q        P  A  P  TPS     T  N  +   + +    P
Sbjct: 1846 --PEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVP 1899



 Score = 75.1 bits (183), Expect = 3e-13
 Identities = 170/677 (25%), Positives = 244/677 (36%), Gaps = 134/677 (19%)

Query: 255 TLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETPPTTQPSFTFTLPA 314
           TLPPP               ++  L   NQA    S +   S     P  Q S    LP 
Sbjct: 44  TLPPPCS----------PAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPL 93

Query: 315 AATASPPT---SLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALSPPKT------ 365
                 PT   +L+ P  +P   +L      P+L   P S+      AL+P         
Sbjct: 94  GTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAF 153

Query: 366 -PSLL---PPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPP------ 415
            P+LL   P + +++SG    L +P   S+P T L   +P+  +     T +PP      
Sbjct: 154 PPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNL-NKVPSEVVPNPKGTPSPPCIVSTV 212

Query: 416 ---------TLQAETATKPQAT-----SAPSPAPKQ----SFLFGTQNTS------PSSP 451
                    ++Q+  A+ PQ T     +  SP  K     S L   QN        P SP
Sbjct: 213 PYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSP 272

Query: 452 AAPAASSASPMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFS 511
             PAA S S    P+ T+  K+        GP+     P S       S  AP  Q  F 
Sbjct: 273 --PAALSLSTQSLPVVTSSQKTA-------GPNTPPDFPISLG-----SHLAPLHQSSFG 318

Query: 512 S---MGPPASVPLPAPFFK-----QTTTPATAPTTTA-----PLFTGLASATSA----VA 554
           S   +G      L  P  K      ++T A+ P+  +     P    +  AT A    VA
Sbjct: 319 SVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVA 378

Query: 555 PITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMG 614
           P     PST S+   +    +N  +S S+S TTS         L  +P A+      A  
Sbjct: 379 PSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSL-------ILKSSPNATYHYPLVAQM 431

Query: 615 SIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLT 674
            +   G  P +   T   T + +  T    AT  S    SG  S +  ++PA      + 
Sbjct: 432 PVSSVGTTPLV--VTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVA 489

Query: 675 FSNTST---PTFNIPFGSSAKSP-----LPS-----YPGANP-QPAFGAAEGQPPGAAKP 720
               ST    T  IP       P     LPS     +P     Q    + EG P   A+ 
Sbjct: 490 PKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQA 549

Query: 721 ALTPSFGSSFTFGNSAAPA-----PATAPTP----APASTIKIVPAHVPTPIQPTFGGAT 771
            LT     +      AAP       +T+ +P    +P +T+       P PI       T
Sbjct: 550 GLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMT 609

Query: 772 HSAFGLKATAS-----AFGAPASSQPAFGGS-----TAVFSFGAATSSGFGATTQTASSG 821
            S  G+ ++AS     ++  P S+ P    S      A F   +A  +G   TT   + G
Sbjct: 610 -SPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTT---AKG 665

Query: 822 SSSSVFGSTTPSPFTFG 838
           +S+    +TT SPF  G
Sbjct: 666 TSTY---TTTASPFLEG 679



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 101/432 (23%), Positives = 153/432 (35%), Gaps = 55/432 (12%)

Query: 471 PKSEKEGPTPPGPSVTATAPSSSSLPTTTS--TTAPTFQPVFSSMGPPASVPLPAPFFKQ 528
           P +E+E P P   + TA  P SS+L  T +     PT  P  S    P   PL A     
Sbjct: 10  PATEQELPQP--QAETAVLPMSSALSVTAALGQPGPTLPPPCSP--APQQCPLSA---AN 62

Query: 529 TTTPATAPTTTA--PLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTT 586
             +P  +P+T A  PL      ++S  A     +P   +       F  N +        
Sbjct: 63  QASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPT-------FLPNLIGPPISPAA 115

Query: 587 TSTATAASQPFLFGAPQASA-------ASFTPAMGSIFQFGKPPAL---PTTTTVTTFSQ 636
            + A+    P L G P +SA       A  +    S F    PP L   P +  V     
Sbjct: 116 LALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAF----PPNLLTSPPSVAVAESGS 171

Query: 637 SLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLP 696
            +  + P A S    + +   S +  +   T S P +    ++ P   +   +S +S + 
Sbjct: 172 VITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIV---STVPYHCVTPMASIQSGVA 228

Query: 697 SYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVP 756
           S P   P      A    P      ++    S    G+ +   P + P     ST  +  
Sbjct: 229 SLPQTTPTTTLAIAS---PQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSL-- 283

Query: 757 AHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAATSSGFGATTQ 816
             V T  Q T G  T   F +  +  +  AP   Q +FG    +   G +  S    T +
Sbjct: 284 -PVVTSSQKTAGPNTPPDFPI--SLGSHLAPL-HQSSFGSVQLLGQTGPSALS--DPTVK 337

Query: 817 TASSGSSSSVFGSTTPS------PFTFGGSAAPAGSGSFGINVATPGSSATTGAFSFGAG 870
           T S   SS+  G++ PS      P        PA   +F + VA       +   S    
Sbjct: 338 TISVDHSST--GASYPSQRSVIPPLPSRNEVVPATVAAFPV-VAPSVDKGPSTISSITCS 394

Query: 871 QSGSTATSTPFT 882
            SGS   +T F+
Sbjct: 395 PSGSLNVATSFS 406


>gi|167736355 mucin 4 isoform a [Homo sapiens]
          Length = 5284

 Score =  122 bits (305), Expect = 2e-27
 Identities = 230/995 (23%), Positives = 375/995 (37%), Gaps = 151/995 (15%)

Query: 32   SSPSSNAPDPCAKETVLSALKEKKKKRTVEEEDQIFLDGQENKRRRHDSSGSGHSAFEPL 91
            S+ +S +PD  A  T     +  +     +  +      +         S SG S   P 
Sbjct: 757  SASASTSPDTAAAMTHTHQAESTEASGQTQTSEPASSGSRTTSAGTATPSSSGASGTTPS 816

Query: 92   VASGVPASFVPKPGSLKRGLNSQSSDDHLNKR-----SRSSSMSSL---TGAYTSGIPSS 143
             + G+  S     G   R  ++ S D H  +      S S+S  ++   TG  +S +P +
Sbjct: 817  GSEGISTS-----GETTRFSSNPSRDSHTTQSTTELLSASASHGAIPVSTGMASSIVPGT 871

Query: 144  SRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRSQTPERPAKKIREEELCHHSSSST 203
                ++ + ++ R   Q      PS+SP  + A SR    +R               + T
Sbjct: 872  FHPTLSEASTAGRPTGQS-SPTSPSASPQETAAISRMAQTQR---------------TRT 915

Query: 204  PLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTL------- 256
               +D  S   +A DT         S ++ G +  +     L PS  G+  T        
Sbjct: 916  SRGSDTISLASQATDTFSTVPPTPPSITSTGLTSPQTETHTLSPSGSGKTFTTALISNAT 975

Query: 257  PPPPQLGYSIT-------------------AEDLDLEKKASLQWFNQALEDKSDAASNSV 297
            P P     S +                   A  L +   +S+   +      +D +S S 
Sbjct: 976  PLPVTYASSASTGHTTPLHVTDASSVSTGHATPLPVTSPSSVSTGHTTPLPVTDTSSEST 1035

Query: 298  TETPPTTQPSFTFTLPAAATASPPTSLLAPSTN---PL-LESLKKMQTPPSLP-PCPESA 352
                P    SF+      +T  P T   + ST    PL + SL    T  + P P  +++
Sbjct: 1036 GHVTPLPVTSFSSASTGDSTPLPVTDTSSASTGHVTPLPVTSLSSASTGDTTPLPVTDTS 1095

Query: 353  GAATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTK 412
             A+T  A S P T +     G +        P P  D+   +T        + +P TDT 
Sbjct: 1096 SASTGHATSLPVTDTSSVSTGHTT-------PLPVTDTSSAST-----GHATSLPVTDTS 1143

Query: 413  APPT--------LQAETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFK 464
            +  T          A +A+  QAT  P P    S +  T +T+P    +P+++S      
Sbjct: 1144 SVSTGHTTPLHVTDASSASTGQAT--PLPVTSLSSV-STGDTTPLPVTSPSSASTGHA-T 1199

Query: 465  PIFTAPPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLP-- 522
            P+      S   G   P P   A     SS+ T  +T+ P   P  +S G    +P+   
Sbjct: 1200 PLLVTDTSSASTGHATPLPVTDA-----SSVSTDHATSLPVTIPSAASTGHTTPLPVTDT 1254

Query: 523  ---------APFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGF 573
                     +     T++ +T  TT  P+ +  +++T  V P+   SPS+ S    A   
Sbjct: 1255 SSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGH-ATPL 1313

Query: 574  GINSVSSSS--------VSTTTSTATAASQPF-LFGAPQASAASFTPAM---GSIFQFGK 621
             + S+SS+S        V++ +S +T  + P  +  A   S    TP      S    G+
Sbjct: 1314 PVTSLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLHVTDASSASTGQ 1373

Query: 622  PPALPTTTTVTTFSQSLPTAVPTATSSSAA----------DFSGFGSTLATSAPATSSQP 671
               LP T+ +++ S    T +P  + SSA+          D S   +  AT  P T +  
Sbjct: 1374 ATPLPVTS-LSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPLPVTDASS 1432

Query: 672  TLTFSNTSTPTFNIPFGSSA--KSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSS 729
              T   TS P   IP  +S    +PLP    ++      A+ GQ       +L  +  SS
Sbjct: 1433 VSTDHATSLPV-TIPSAASTGHTTPLPVTDTSS------ASTGQAT-----SLLVTDTSS 1480

Query: 730  FTFGNSAAPAPATAPTPAPASTIKIVPAHVPTPIQPTFGGATH---SAFGLKATASAFGA 786
             + G++  P P T+ + A  ST  + P HV +P   + G AT    ++    +T      
Sbjct: 1481 VSTGDTT-PLPVTSTSSA--STGHVTPLHVTSPSSASTGHATPLPVTSLSSASTGDTMPL 1537

Query: 787  PASS-QPAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAG 845
            P +S   A  G T       A+S   G TT    +  SS+  G TTP P T   SA+   
Sbjct: 1538 PVTSPSSASTGDTTPLPVTDASSVSTGHTTPLPVTSPSSASTGHTTPLPVTDTSSASKGD 1597

Query: 846  SGSFGINVATPGSSATTGAFSFGAGQSGSTATSTPFTGGLGQNALGTTGQSTPF---AFN 902
            +    +   +  S+  T         S ST  +TP    +   +  +TG +TP    + +
Sbjct: 1598 TTPLPVTSPSSASTGHTTPLPVTDTSSASTGDTTPLP--VTNASSLSTGHATPLHVTSPS 1655

Query: 903  VGSTTESKPV-FGGTATPTFGQNTPAPGVGTSGSS 936
              ST  + P+    T++ + G  TP P  G S ++
Sbjct: 1656 SASTGHATPLPVTSTSSASTGHATPLPVTGLSSAT 1690



 Score =  119 bits (299), Expect = 1e-26
 Identities = 236/937 (25%), Positives = 349/937 (37%), Gaps = 164/937 (17%)

Query: 124  SRSSSMSSLTGA-----YTSGIPSSSRNAITS-SYSSTRGISQLWKRNGPSSSPFSSPAS 177
            S S+++   TGA     +T    ++    ++S SYS T+ I         ++SP SSP  
Sbjct: 550  SHSTTLPKTTGAGAQTQWTQETGTTGEALLSSPSYSVTQMIKT-------ATSPSSSPML 602

Query: 178  SRSQTPERPAKKIREEELCHHSSSSTPLAADKESQGEKAADTTPRKKQNSNSQS------ 231
             R  + +            H +S+S   +     +G   A  T ++ Q + S S      
Sbjct: 603  DRHTSQQITTAPSTNHSTIHSTSTSPQESPAVSQRGHTQAPQTTQESQTTRSVSPMTDTK 662

Query: 232  ---TPGS----SGQRKRKV--QLLPSRRGEQLTLPPPPQLGYSITAEDLDLE-----KKA 277
               TPGS    SG    ++  Q  P+        P P   G++  A    L+       A
Sbjct: 663  TVTTPGSSFTASGHSPSEIVPQDAPTISAATTFAPAPTGDGHTTQAPTTALQAAPSSHDA 722

Query: 278  SLQWFNQALEDKSDA--ASNSVTETPPTTQPSFTFTLPAAATASPPTSLLAPSTNPLLES 335
            +L         K+ A   +NSV  TP   +  +T    A+A+ SP T+     T+    +
Sbjct: 723  TLGPSGGTSLSKTGALTLANSVVSTPGGPEGQWT---SASASTSPDTAAAMTHTHQAEST 779

Query: 336  LKKMQTPPSLPPCPESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLPS---------P 386
                QT  S    P S+G+ TT A     TPS     G + SG  G+  S         P
Sbjct: 780  EASGQTQTSE---PASSGSRTTSA--GTATPSSSGASGTTPSGSEGISTSGETTRFSSNP 834

Query: 387  SFDS---KPPTTLL------GLIP-----APSMVPATDTKAPPTL-QAETATKPQATS-- 429
            S DS   +  T LL      G IP     A S+VP T     PTL +A TA +P   S  
Sbjct: 835  SRDSHTTQSTTELLSASASHGAIPVSTGMASSIVPGT---FHPTLSEASTAGRPTGQSSP 891

Query: 430  -APSPAPKQ----SFLFGTQ--NTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPPG 482
             +PS +P++    S +  TQ   TS  S     AS A+  F  +   PP     G T P 
Sbjct: 892  TSPSASPQETAAISRMAQTQRTRTSRGSDTISLASQATDTFSTVPPTPPSITSTGLTSPQ 951

Query: 483  PSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAP---TTT 539
                  +PS S    TT+  +              + PLP  +    +T  T P   T  
Sbjct: 952  TETHTLSPSGSGKTFTTALIS-------------NATPLPVTYASSASTGHTTPLHVTDA 998

Query: 540  APLFTGLASATSAVAPI------TSASPSTDSASK--------PAFGFGINSVSSSS--- 582
            + + TG A+     +P       T+  P TD++S+        P   F   S   S+   
Sbjct: 999  SSVSTGHATPLPVTSPSSVSTGHTTPLPVTDTSSESTGHVTPLPVTSFSSASTGDSTPLP 1058

Query: 583  VSTTTSTATAASQPF-LFGAPQASAASFTP---AMGSIFQFGKPPALPTTTTVTTFSQSL 638
            V+ T+S +T    P  +     AS    TP      S    G   +LP T T ++ S   
Sbjct: 1059 VTDTSSASTGHVTPLPVTSLSSASTGDTTPLPVTDTSSASTGHATSLPVTDT-SSVSTGH 1117

Query: 639  PTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAK----SP 694
             T +P   +SSA+      +  ATS P T    T + S   T   ++   SSA     +P
Sbjct: 1118 TTPLPVTDTSSAS------TGHATSLPVTD---TSSVSTGHTTPLHVTDASSASTGQATP 1168

Query: 695  LP-------SYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPA 747
            LP       S     P P    +     G A P L     S+ T    A P P T  +  
Sbjct: 1169 LPVTSLSSVSTGDTTPLPVTSPSSAS-TGHATPLLVTDTSSAST--GHATPLPVTDASSV 1225

Query: 748  PASTIKIVPAHVPT----------PIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGS 797
                   +P  +P+          P+  T   +T  A  L  T ++  +   + P    S
Sbjct: 1226 STDHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVTS 1285

Query: 798  TAVFSFGAAT--------SSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSF 849
            T+  S G  T        S+  G  T    +  SS+  G T P P T   SA+   +   
Sbjct: 1286 TSSASTGHVTPLHVTSPSSASTGHATPLPVTSLSSASTGDTMPLPVTSPSSASTGDTTPL 1345

Query: 850  GINVATPGSSATTGAFSFGAGQSGSTATSTPFTGGLGQNALGTTGQSTPFAF---NVGST 906
             +  A+  S+  T         S ST  +TP    +   +  +TG +TP      +  ST
Sbjct: 1346 PVTDASSVSTGHTTPLHVTDASSASTGQATPLP--VTSLSSVSTGDTTPLPVTSPSSAST 1403

Query: 907  TESKPVF-GGTATPTFGQNTPAPGVGTSGSSLSFGAS 942
              + P+    T++ + G  TP P    S  S     S
Sbjct: 1404 GHATPLLVTDTSSASTGHATPLPVTDASSVSTDHATS 1440



 Score =  111 bits (277), Expect = 4e-24
 Identities = 213/920 (23%), Positives = 350/920 (38%), Gaps = 126/920 (13%)

Query: 113  SQSSDDHLNKRSRSSSMSSLTGAYTSGIPSSSRNAITSSYSSTRGISQLWKRNGPSSSPF 172
            S +S  H      +S+ S+ TG  T+ +P +   + ++  ++   ++     +   ++P 
Sbjct: 2567 SAASTGHATPLPVTSTSSASTGD-TTPLPVTDTYSASTGQATPLPVTDTSSASTGDTTPL 2625

Query: 173  ----SSPASSRSQTPERPAKKIREEELCHHSSSSTPLAADKESQGEKAADTTPRKKQNSN 228
                +S AS+   TP  P          H    +TPL     S       TTP    +++
Sbjct: 2626 PVTDTSSASTGHATP-LPVTNTSSVSTGH----ATPLHVTSPSSAS-TGHTTPLPVTDAS 2679

Query: 229  SQSTPGSS------------GQRKRKVQLLPSRRGEQLTLPPPPQLGYSIT---AEDLDL 273
            S ST  ++            G        +PS      T P P     S++   A  L +
Sbjct: 2680 SVSTGHATSLPVTDASSVFTGHATSLPVTIPSSASSGHTTPLPVTDASSVSTGHATSLPV 2739

Query: 274  EKKASLQWFNQALEDKSDAASNSVTETPPTTQPSFTFTLPAAATASPPTSLLAPSTN--- 330
               +S+   +      +DA+S S     P    S +       T  P T   + ST    
Sbjct: 2740 TDASSVSTGHATPLPVTDASSVSTGHATPLPLTSLSSVSTGDTTPLPVTDTSSASTGQAT 2799

Query: 331  PL-LESLKKMQTPPSLP-PCPESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSF 388
            PL + SL  + T  + P P  +++ A+T  A S P T +       S +      P P  
Sbjct: 2800 PLPVTSLSSVSTGDTTPLPVTDTSSASTGHATSLPVTDT-------SSASTGHATPLPDT 2852

Query: 389  DSKPPTTLLGLIPAPSMVPATDTKAPPTLQAE----TATKPQATSAPSPAPKQSFLFGTQ 444
            D+   +T        +++P TDT +     A     T T   +T   +P    S    + 
Sbjct: 2853 DTSSAST-----GHATLLPVTDTSSASIGHATSLPVTDTSSISTGHATPLHVTSPSSAST 2907

Query: 445  NTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPPGPSVTATAPSS------------ 492
              +   P    +S+++    P+    P S   G   P P VT T+ +S            
Sbjct: 2908 GHATPLPVTDTSSASTGHANPLHVTSPSSASTGHATPLP-VTDTSSASTGHATPLPVTSL 2966

Query: 493  SSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSA 552
            SS+ T  +T  P   P  +S G   + PLP      T++ +T   T  P+ +  +++T  
Sbjct: 2967 SSVSTGDTTPLPVTSPSSASTGH--TTPLPVT---DTSSASTGQATALPVTSTSSASTGD 3021

Query: 553  VAP--ITSASPSTDSASKPAFGFGINSVSSSS-----VSTTTSTATAASQPFLF-GAPQA 604
              P  +T  S ++   + P     ++SVS+       V++ +S +T  + P L   A  A
Sbjct: 3022 TTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSA 3081

Query: 605  SAASFTP----AMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAA--------- 651
            S    TP    ++ S+   G    LP T+  ++ S    T++P   +SSA+         
Sbjct: 3082 STGQATPLPVTSLSSV-STGDTTPLPVTSP-SSASTGHATSLPVTDTSSASTGDTTSLPV 3139

Query: 652  -DFSGFGSTLATSAPATSSQPTLTFSNTS---TPTFNIPFGSSAKSPLPSYPGANPQPAF 707
             D S   +   TS P T +  + T   T    T T ++  G +    +     A+   A 
Sbjct: 3140 TDTSSAYTGDTTSLPVTDTSSSSTGDTTPLLVTETSSVSTGHATPLLVTDASSASTGHAT 3199

Query: 708  GAAEGQPPGAAKPALTP---SFGSSFTFGNSAAPAPATAPTPAPASTIKIVPAH------ 758
                  P  A+    TP   +  SS + G+ A P P T  + A       +P        
Sbjct: 3200 PLHVTSPSSASTGDTTPVPVTDTSSVSTGH-ATPLPVTGLSSASTGDTTRLPVTDISSAS 3258

Query: 759  ----VPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAAT------- 807
                 P P+  T   +T     L  T+ +  +   + P    ST+  S G AT       
Sbjct: 3259 TGQATPLPVTNTSSVSTGDTMPLPVTSPSSASTGHATPLPVTSTSSASTGHATPVPVTST 3318

Query: 808  -SSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATTGAFS 866
             S+  G TT    + +SS+  G TTP P T   SA+   +    + + +  S+  T    
Sbjct: 3319 SSASTGHTTPLPVTDTSSASTGDTTPLPVTSPSSASTGHTTPLHVTIPSSASTGDTSTLP 3378

Query: 867  FGAGQSGSTATSTPFTGGLGQNALGTTGQSTPF------AFNVGSTTESKPVFGGTATPT 920
                 S ST  +TP    +   +  +TG +TP       + + G TT   PV   ++  T
Sbjct: 3379 VTGASSASTGHATPLP--VTDTSSVSTGHATPLPVTSLSSVSTGDTT-PLPVTDASSAST 3435

Query: 921  FGQNTPAPGVGTSGSSLSFG 940
             GQ TP P   TS SS+S G
Sbjct: 3436 -GQATPLP--VTSLSSVSTG 3452



 Score =  111 bits (277), Expect = 4e-24
 Identities = 213/909 (23%), Positives = 339/909 (37%), Gaps = 120/909 (13%)

Query: 80   SSGSGHSAFEPLV-ASGVPASFVPKPGSLKRGLNSQSSDDHLNKRSRSSSMSSLTGAYTS 138
            S  +GH+   P+  AS V   F     SL   + S +S  H      + + S  TG  TS
Sbjct: 2680 SVSTGHATSLPVTDASSV---FTGHATSLPVTIPSSASSGHTTPLPVTDASSVSTGHATS 2736

Query: 139  GIPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRSQTPERPAKKIREEELCHH 198
             +P +  +++++ +++   ++     +   ++P    + S   T +     + +      
Sbjct: 2737 -LPVTDASSVSTGHATPLPVTDASSVSTGHATPLPLTSLSSVSTGDTTPLPVTDTSSAS- 2794

Query: 199  SSSSTPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPP 258
            +  +TPL     S      DTTP    +++S ST  ++         LP      +T   
Sbjct: 2795 TGQATPLPVTSLSS-VSTGDTTPLPVTDTSSASTGHATS--------LP------VTDTS 2839

Query: 259  PPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETPPTTQPSFT--------F 310
                G++    D D    ++       + D S A+    T  P T   S +         
Sbjct: 2840 SASTGHATPLPDTDTSSASTGHATLLPVTDTSSASIGHATSLPVTDTSSISTGHATPLHV 2899

Query: 311  TLPAAATASPPTSLLAPST--------NPL-LESLKKMQTPPSLP-PCPESAGAATTEAL 360
            T P++A+    T L    T        NPL + S     T  + P P  +++ A+T  A 
Sbjct: 2900 TSPSSASTGHATPLPVTDTSSASTGHANPLHVTSPSSASTGHATPLPVTDTSSASTGHA- 2958

Query: 361  SPPKTPSLLPPLGLSQSGPPGLLP--SPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQ 418
                TP  +  L    +G    LP  SPS  S   TT L         P TDT +  T Q
Sbjct: 2959 ----TPLPVTSLSSVSTGDTTPLPVTSPSSASTGHTTPL---------PVTDTSSASTGQ 3005

Query: 419  AE----TATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSE 474
            A     T+T   +T   +P P       +   +   P    +S ++    P+    P S 
Sbjct: 3006 ATALPVTSTSSASTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSA 3065

Query: 475  KEGPTPP-----------GPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPA 523
              G   P           G +      S SS+ T  +T  P   P  +S G   S+P+  
Sbjct: 3066 STGHATPLLVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATSLPVT- 3124

Query: 524  PFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSV 583
                 T++ +T  TT+ P+       +SA    T++ P TD++S           +   V
Sbjct: 3125 ----DTSSASTGDTTSLPV----TDTSSAYTGDTTSLPVTDTSSSST-----GDTTPLLV 3171

Query: 584  STTTSTATAASQPFLF-GAPQASAASFTP----AMGSIFQFGKPPALPTTTTVTTFSQSL 638
            + T+S +T  + P L   A  AS    TP    +  S       P   T T+  +   + 
Sbjct: 3172 TETSSVSTGHATPLLVTDASSASTGHATPLHVTSPSSASTGDTTPVPVTDTSSVSTGHAT 3231

Query: 639  PTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSY 698
            P  V   +S+S  D +    T  +SA    + P L  +NTS+ +          SP  + 
Sbjct: 3232 PLPVTGLSSASTGDTTRLPVTDISSASTGQATP-LPVTNTSSVSTGDTMPLPVTSPSSAS 3290

Query: 699  PG-ANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVPA 757
             G A P P    +     G A P    S  S+ T      P P T    + AST    P 
Sbjct: 3291 TGHATPLPVTSTSSAST-GHATPVPVTSTSSAST--GHTTPLPVT--DTSSASTGDTTPL 3345

Query: 758  HVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAATSSGFGATTQT 817
             V +P   + G  T     + ++AS             G T+      A+S+  G  T  
Sbjct: 3346 PVTSPSSASTGHTTPLHVTIPSSAST------------GDTSTLPVTGASSASTGHATPL 3393

Query: 818  ASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATTGAFSFGAGQSGSTAT 877
              + +SS   G  TP P T   S +   +    +  A+  S+         +  S ST  
Sbjct: 3394 PVTDTSSVSTGHATPLPVTSLSSVSTGDTTPLPVTDASSASTGQATPLPVTSLSSVSTGD 3453

Query: 878  STPFTGGLGQNALGTTGQSTPF------AFNVGSTTESKPVFGGTATPTFGQNTPAPGVG 931
            +TP    +   +  +TG +TP       + + G TT   PV   T++ + GQ TP P   
Sbjct: 3454 TTPLL--VTDASSVSTGHATPLPVTDTSSASTGDTTR-LPV-TDTSSASTGQATPLP--V 3507

Query: 932  TSGSSLSFG 940
            TS SS+S G
Sbjct: 3508 TSLSSVSTG 3516



 Score =  107 bits (266), Expect = 7e-23
 Identities = 209/902 (23%), Positives = 328/902 (36%), Gaps = 119/902 (13%)

Query: 136  YTSGIPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSP--ASSRSQTPERPAKKIREE 193
            +T+  P+++  A  SS+ +T G S      G S S   +   A+S   TP  P     E 
Sbjct: 704  HTTQAPTTALQAAPSSHDATLGPS-----GGTSLSKTGALTLANSVVSTPGGP-----EG 753

Query: 194  ELCHHSSSSTPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQRKRKV-QLLPSRRGE 252
            +    S+S++P  A   +   +A  T   +       S P SSG R        PS  G 
Sbjct: 754  QWTSASASTSPDTAAAMTHTHQAEST---EASGQTQTSEPASSGSRTTSAGTATPSSSGA 810

Query: 253  QLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETPPTT-------Q 305
              T P   + G S + E        S          +  +AS S    P +T        
Sbjct: 811  SGTTPSGSE-GISTSGETTRFSSNPSRDSHTTQSTTELLSASASHGAIPVSTGMASSIVP 869

Query: 306  PSFTFTLPAAATASPPT---SLLAPSTNPL-LESLKKM---------------------- 339
             +F  TL  A+TA  PT   S  +PS +P    ++ +M                      
Sbjct: 870  GTFHPTLSEASTAGRPTGQSSPTSPSASPQETAAISRMAQTQRTRTSRGSDTISLASQAT 929

Query: 340  QTPPSLPPCPESAGAATTEALSPPKTPS-LLPPLGLSQSGPPGLL----PSP----SFDS 390
             T  ++PP P S    T+  L+ P+T +  L P G  ++    L+    P P    S  S
Sbjct: 930  DTFSTVPPTPPSI---TSTGLTSPQTETHTLSPSGSGKTFTTALISNATPLPVTYASSAS 986

Query: 391  KPPTTLLGLIPAPSMVPATDTKAPPTLQAE-----------TATKPQATSAPSPAPKQSF 439
               TT L +  A S+     T  P T  +            T T  ++T   +P P  SF
Sbjct: 987  TGHTTPLHVTDASSVSTGHATPLPVTSPSSVSTGHTTPLPVTDTSSESTGHVTPLPVTSF 1046

Query: 440  LFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSSSLPTTT 499
               +   S   P    +S+++    P+      S   G T P P VT T+ +S+   T+ 
Sbjct: 1047 SSASTGDSTPLPVTDTSSASTGHVTPLPVTSLSSASTGDTTPLP-VTDTSSASTGHATSL 1105

Query: 500  STTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAP--IT 557
              T        SS+    + PLP      T++ +T   T+ P+    + +T    P  +T
Sbjct: 1106 PVTDT------SSVSTGHTTPLPV---TDTSSASTGHATSLPVTDTSSVSTGHTTPLHVT 1156

Query: 558  SASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIF 617
             AS ++   + P     +   S SSVST  +T    + P       A+    T    +  
Sbjct: 1157 DASSASTGQATP-----LPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSAST 1211

Query: 618  QFGKP-PALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFS 676
                P P    ++  T  + SLP  +P+A S+        G T  T  P T +    T  
Sbjct: 1212 GHATPLPVTDASSVSTDHATSLPVTIPSAAST--------GHT--TPLPVTDTSSASTGQ 1261

Query: 677  NTS---TPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFG 733
             TS   T T ++  G +   P+ S   A+           P  A+    TP   +S +  
Sbjct: 1262 ATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTSLSSA 1321

Query: 734  NSAAPAPATAPTPAPASTIKIVPAHVPTPIQPTFGGAT--HSAFGLKA-TASAFGAPASS 790
            ++    P    +P+ AST    P  V      + G  T  H      A T  A   P +S
Sbjct: 1322 STGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLHVTDASSASTGQATPLPVTS 1381

Query: 791  QPAFG-GSTAVFSFGAATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSF 849
              +   G T      + +S+  G  T    + +SS+  G  TP P T   S +   + S 
Sbjct: 1382 LSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPLPVTDASSVSTDHATSL 1441

Query: 850  GINVATPGSSATTGAFSFGAGQSGSTATSTPFTGGLGQNALGTTGQSTPFAFNVGSTTES 909
             + + +  S+  T         S ST  +T     +   +  +TG +TP        T +
Sbjct: 1442 PVTIPSAASTGHTTPLPVTDTSSASTGQATSLL--VTDTSSVSTGDTTPL-----PVTST 1494

Query: 910  KPVFGGTATPTFGQNTPAPGVGTSGSSLSFGASSAPAQGFVGVGPFGSAAPSFSIGAGSK 969
                 G  TP    +  +P   ++G +     +S  +       P    +PS S   G  
Sbjct: 1495 SSASTGHVTPL---HVTSPSSASTGHATPLPVTSLSSASTGDTMPLPVTSPS-SASTGDT 1550

Query: 970  TP 971
            TP
Sbjct: 1551 TP 1552



 Score =  100 bits (248), Expect = 9e-21
 Identities = 218/925 (23%), Positives = 350/925 (37%), Gaps = 126/925 (13%)

Query: 80   SSGSGHSAFEPLVASGVPASFVPKPGSLKRGLNSQSSDDHLNKRSRSSSMSSLTGAYTSG 139
            S+ +GH+   P+ ++   ++    P  +  GL+S ++DD    R   + +SS +    + 
Sbjct: 1656 SASTGHATPLPVTSTSSASTGHATPLPVT-GLSSATTDD--TTRLPVTDVSSASTGQATP 1712

Query: 140  IPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRSQTPERPAKKIREEELCHHS 199
            +P +S +++++  ++   ++     +   +SP     +S + T +     + +      S
Sbjct: 1713 LPVTSLSSVSTGDTTPLPVTSPSSASTGHASPLLVTDASSASTGQATPLPVTDT-----S 1767

Query: 200  SSSTPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPP 259
            S ST  A      G  +A T    +      S+  S+GQ        PS      T P P
Sbjct: 1768 SVSTAHATPLPVTGLSSASTDDTTRLPVTDVSS-ASTGQAIPLPVTSPSSASTGDTTPLP 1826

Query: 260  PQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETPPTTQPSFTFTLPAAATAS 319
                 S +  D            +  +   S A+S   T  P T   S +     +   +
Sbjct: 1827 VTDASSASTGDTT----------SLPVTIPSSASSGHTTSLPVTDASSVSTGHATSLLVT 1876

Query: 320  PPTSLLAPSTNPL-LESLKKMQTPPSLP-PCPESAGAATTEALSPPKTPSLLPPLGLSQS 377
              +S+    T PL +       T  + P    +++  +T  A S P T      L  + +
Sbjct: 1877 DASSVSTGDTTPLPVTDTNSASTGDTTPLHVTDASSVSTGHATSLPVTS-----LSSAST 1931

Query: 378  GPPGLLP--SPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAETATKPQATSAPSPAP 435
            G    LP  SPS  S   TT L +  A S VP     + P   A + +   AT  P P  
Sbjct: 1932 GDTTPLPVTSPSSASSGHTTPLPVTDASS-VPTGHATSLPVTDASSVSTGHAT--PLPVT 1988

Query: 436  KQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSSSL 495
              S +  T + +P  P    +S ++    P+      S   G T P P VT T+ +S+  
Sbjct: 1989 DASSV-STGHATPL-PVTDTSSVSTGQATPLPVTSLSSASTGDTTPLP-VTDTSSASTGQ 2045

Query: 496  PTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTA-PLFTGLASATSAVA 554
             T    T+       SS+    + PLP       T+P++A T  A PL    AS+ S   
Sbjct: 2046 DTPLPVTS------LSSVSTGDTTPLPV------TSPSSASTGHATPLLVTDASSVST-G 2092

Query: 555  PITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAM- 613
              TS   +  S+        ++   +SS+ST  +T    + P       AS    TP   
Sbjct: 2093 HATSLLVTDASSVSTGHATALHVTDASSLSTGDTTPLPVTSP-----SSASTGDTTPLPV 2147

Query: 614  --GSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAA----------DFSGFGSTLA 661
               S    G   +LP T T ++ S    T++P   +SSA+          D S   +  A
Sbjct: 2148 TDTSSVSTGHATSLPVTDT-SSASTGHATSLPVTDTSSASTGHATPLPVTDTSSASTGQA 2206

Query: 662  TSAPATSSQPTLT---FSNTSTPTFNIPFGSSAKSPLPSYPGAN-----PQPAFGAAEGQ 713
            T  P TS     T        T T +   G +   P+ S   A+     P P   A+   
Sbjct: 2207 TPLPVTSPSSASTGHAIPLLVTDTSSASTGQATPLPVTSLSSASTGDTTPLPVTDASSVS 2266

Query: 714  PPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVPAHV------------PT 761
               A    +T    SS + G++  P P T+P+ A  ST    P HV            P 
Sbjct: 2267 TGHATSLPVTSL--SSVSTGDTT-PLPVTSPSSA--STGHATPLHVTDASSASTGHATPL 2321

Query: 762  PIQPTFGGATHSAFGLKATASAFGAPASSQPAF--------GGSTAVFSFGAATSSGFGA 813
            P+      +T     L  T+ +  +   + P           G T      +++S+  G 
Sbjct: 2322 PVTSLSSASTGDTTPLPVTSPSSASTGHATPLHVTDASSVSTGDTTPLPVTSSSSASSGH 2381

Query: 814  TTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSF---GINVATPG----------SSA 860
            TT    + +SS+  G TTP P T   SA+   +      G++ A+ G          SSA
Sbjct: 2382 TTPLPVTDASSASTGDTTPLPVTDTSSASTGHATHLPVTGLSSASTGDTTRLPVTNVSSA 2441

Query: 861  TTG---AFSFGAGQSGSTATSTPFTGGLGQNALGTTGQSTPF------AFNVGSTTESKP 911
            +TG        +  S ST  +TP  G     +  +TG +TP       + + G TT   P
Sbjct: 2442 STGHATPLPVTSTSSASTGDTTPLPG--TDTSSVSTGHTTPLLVTDASSVSTGDTTR-LP 2498

Query: 912  VFGGTATPTFGQNTPAPGVGTSGSS 936
            V   ++  T G  TP P   T  +S
Sbjct: 2499 VTSPSSAST-GHTTPLPVTDTPSAS 2522



 Score = 98.6 bits (244), Expect = 3e-20
 Identities = 195/867 (22%), Positives = 315/867 (36%), Gaps = 89/867 (10%)

Query: 130  SSLTGAYTSGIPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRSQTPERPAKK 189
            SS +  + + +P +  +++++ +++   ++ L   +   ++P   P +  S      A  
Sbjct: 3383 SSASTGHATPLPVTDTSSVSTGHATPLPVTSLSSVSTGDTTPL--PVTDASSASTGQATP 3440

Query: 190  IREEELCHHSSSSTPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSR 249
            +    L   S+  T      ++        TP    +++S ST  ++  R        + 
Sbjct: 3441 LPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSSASTGDTT--RLPVTDTSSAS 3498

Query: 250  RGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQA----LEDKSDAASNSVTETPPTTQ 305
             G+   LP       S       L   AS      A    + D S A++   T  P T  
Sbjct: 3499 TGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSSASTGDTTRLPVTDT 3558

Query: 306  PSFTFTLPAAATASPPTSLLAPSTNPL-LESLKKMQTPPSLPPCPESAGAATTEALSP-P 363
             S +         + P+S  +  T PL + S   + T    P    S  +A+T  ++P P
Sbjct: 3559 SSASTGQATPLPVTIPSSSSSGHTTPLPVTSTSSVSTGHVTPLHVTSPSSASTGHVTPLP 3618

Query: 364  KTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAETAT 423
             T +     G      P L+   S  S    T L +  A S     DT   P     +A+
Sbjct: 3619 VTSTSSASTG---HATPLLVTDASSVSTGHATPLPVTDASS-ASTGDTTPLPVTDTSSAS 3674

Query: 424  KPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPPGP 483
              QAT  P P    S +  T +T+P  P   A+S+++    P+    P S   G T P P
Sbjct: 3675 TGQAT--PLPVTSLSSV-STGDTTPL-PVTDASSASTGHATPLPVTIPSSVSTGDTMPLP 3730

Query: 484  SVTATAPSSSS------LPTT------TSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTT 531
                T+PSS+S      LP T      T  T P      SS     + PLP      T++
Sbjct: 3731 ---VTSPSSASTGHATPLPVTGLSSASTGDTTPLPVTDTSSASTRHATPLPVT---DTSS 3784

Query: 532  PATAPTTTAPLFTGLASATSAVA---PITSASPSTDSASKPAFGFGINSVSSSSVSTTTS 588
             +T  TT  P+ T ++SA++  A   P+TS S ++   + P     +    +SSVST  +
Sbjct: 3785 ASTDDTTRLPV-TDVSSASTGHATPLPVTSTSSASTGDTTP-----LPVTDTSSVSTGHA 3838

Query: 589  TATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSS 648
            T+   +         A+    T    S    G    LP T+T ++ S    T +P  + S
Sbjct: 3839 TSLPVTSRSSASTGHATPLPVTDT--SSVSTGHATPLPVTST-SSVSTGHATPLPVTSPS 3895

Query: 649  SAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFG 708
            SA+      +  AT  P TS+    T   T  P  N                     +  
Sbjct: 3896 SAS------TGHATPVPVTSTSSASTGDTTPLPVTNAS-------------------SLS 3930

Query: 709  AAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVPAH--VPTPIQPT 766
                 P     P+      +S      A+ A     TP P +++  V      P P+  T
Sbjct: 3931 TGHATPLHVTSPSSASRGDTSTLPVTDASSASTGHATPLPLTSLSSVSTGDTTPLPVTDT 3990

Query: 767  FGGATHSAFGLKATASAFGAPASSQP--------AFGGSTAVFSFGAATSSGFGATTQTA 818
               +T  A  L  T+ +  +   + P        A  G T       A+S   G  T   
Sbjct: 3991 SSASTGQATPLPVTSLSSVSTGDTTPLPVTIPSSASSGHTTSLPVTDASSVSTGHGTPLP 4050

Query: 819  SSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATTGAFSFGAGQSGSTATS 878
             + +SS+  G TTP P T   SA+   +    +   +  S+         +  S ST  +
Sbjct: 4051 VTSTSSASTGDTTPLPVTDTSSASTGHATPLPVTDTSSASTGHATPLPVTSLSSVSTGHA 4110

Query: 879  TPFTGGLGQNALGTTGQSTPFAFNVGSTTESKPVFGGTATPTFGQNTPAPGVGTSGSSLS 938
            TP       +A   +  S       G TT S    GG  T T    T +  + ++  S +
Sbjct: 4111 TPLAVSSATSASTVSSDSPLKMETPGMTTPSLKTDGGRRTATSPPPTTSQTIISTIPSTA 4170

Query: 939  FGASSAPA------QGFVGVGPFGSAA 959
                S  A      +  V + P+G+ A
Sbjct: 4171 MHTRSTAAPIPILPERGVSLFPYGAGA 4197



 Score = 95.1 bits (235), Expect = 3e-19
 Identities = 206/888 (23%), Positives = 316/888 (35%), Gaps = 161/888 (18%)

Query: 199  SSSSTPLAAD---KESQGEKAADTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLT 255
            SS+ST  A      ++      DTTP    +++S ST            + P      +T
Sbjct: 1463 SSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSASTG----------HVTPLH----VT 1508

Query: 256  LPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETPPTTQPSF----TFT 311
             P     G++       L   ++       +   S A++   T  P T   S     T  
Sbjct: 1509 SPSSASTGHATPLPVTSLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTP 1568

Query: 312  LPAAATASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALSPPKTPSLLPP 371
            LP  + +S  T    P       S  K  T P     P SA    T       TP  LP 
Sbjct: 1569 LPVTSPSSASTGHTTPLPVTDTSSASKGDTTPLPVTSPSSASTGHT-------TP--LPV 1619

Query: 372  LGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAETATKPQATSAP 431
               S +      P P  ++   +T     P     P++ +    T    T+T   +T   
Sbjct: 1620 TDTSSASTGDTTPLPVTNASSLSTGHAT-PLHVTSPSSASTGHATPLPVTSTSSASTGHA 1678

Query: 432  SPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPPGPSVTATAPS 491
            +P P       T + +   P    +S+++    P+      S   G T P P    T+PS
Sbjct: 1679 TPLPVTGLSSATTDDTTRLPVTDVSSASTGQATPLPVTSLSSVSTGDTTPLP---VTSPS 1735

Query: 492  SSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASAT- 550
            S+S    T   +P      SS     + PLP      T++ +TA  T  P+ TGL+SA+ 
Sbjct: 1736 SAS----TGHASPLLVTDASSASTGQATPLPV---TDTSSVSTAHATPLPV-TGLSSAST 1787

Query: 551  --SAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTT--------STATAASQPFLFG 600
              +   P+T  S ++   + P     + S SS+S   TT        S +T  +      
Sbjct: 1788 DDTTRLPVTDVSSASTGQAIP---LPVTSPSSASTGDTTPLPVTDASSASTGDTTSLPVT 1844

Query: 601  APQASAASFTPAM----GSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAA----- 651
             P ++++  T ++     S    G   +L   T  ++ S    T +P   ++SA+     
Sbjct: 1845 IPSSASSGHTTSLPVTDASSVSTGHATSL-LVTDASSVSTGDTTPLPVTDTNSASTGDTT 1903

Query: 652  -----DFSGFGSTLATSAPATS--------------SQPTLTFSNTSTP-----TFNIPF 687
                 D S   +  ATS P TS              + P+   S  +TP       ++P 
Sbjct: 1904 PLHVTDASSVSTGHATSLPVTSLSSASTGDTTPLPVTSPSSASSGHTTPLPVTDASSVPT 1963

Query: 688  GSSAKSPLP-----SYPGANPQPAFGAA---------------EGQPPGAAKPALTPSFG 727
            G +   P+      S   A P P   A+                    G A P    S  
Sbjct: 1964 GHATSLPVTDASSVSTGHATPLPVTDASSVSTGHATPLPVTDTSSVSTGQATPLPVTSLS 2023

Query: 728  SSFTFGNSAAPAPATA------PTPAPASTIKIVPAHVPTPI---QPTFGGATHSAFGLK 778
            S+ T   +  P   T+       TP P +++  V     TP+    P+     H+   L 
Sbjct: 2024 SASTGDTTPLPVTDTSSASTGQDTPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLV 2083

Query: 779  ATASAFG--------APASSQPAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSVFGST 830
              AS+             +S  + G +TA+    A++ S  G TT    +  SS+  G T
Sbjct: 2084 TDASSVSTGHATSLLVTDASSVSTGHATALHVTDASSLS-TGDTTPLPVTSPSSASTGDT 2142

Query: 831  TPSPFTFGGSAAPAGSGSFGINVATPGSSATTG-AFSFGAGQSGSTATSTPFTGGLGQNA 889
            TP P T   S +   + S  +   T  SSA+TG A S     + S +T       +   +
Sbjct: 2143 TPLPVTDTSSVSTGHATSLPV---TDTSSASTGHATSLPVTDTSSASTGHATPLPVTDTS 2199

Query: 890  LGTTGQSTPFAFNVGST-----------TESKPVFGGTATP---------TFGQNTPAPG 929
              +TGQ+TP      S+           T++     G ATP         + G  TP P 
Sbjct: 2200 SASTGQATPLPVTSPSSASTGHAIPLLVTDTSSASTGQATPLPVTSLSSASTGDTTPLP- 2258

Query: 930  VGTSGSSLSFG-ASSAPAQGFVGVG-----PFGSAAPSFSIGAGSKTP 971
              T  SS+S G A+S P      V      P    +PS S   G  TP
Sbjct: 2259 -VTDASSVSTGHATSLPVTSLSSVSTGDTTPLPVTSPS-SASTGHATP 2304



 Score = 93.6 bits (231), Expect = 8e-19
 Identities = 223/943 (23%), Positives = 344/943 (36%), Gaps = 132/943 (13%)

Query: 110  GLNSQSSDDHLNKRSRSSSMSSLTGAYTSGI--PSSSRNAITSSYSSTRGISQLWKRNGP 167
            GL+S S+DD         S +S   A    +  PSS+    T+    T   S        
Sbjct: 1781 GLSSASTDDTTRLPVTDVSSASTGQAIPLPVTSPSSASTGDTTPLPVTDASSA--STGDT 1838

Query: 168  SSSPFSSPASSRS-QTPERPAKKIREEELCHHSSSSTPLAADKESQGEKAADTTPRKKQN 226
            +S P + P+S+ S  T   P          H +S    L  D  S      DTTP    +
Sbjct: 1839 TSLPVTIPSSASSGHTTSLPVTDASSVSTGHATSL---LVTDASSVS--TGDTTPLPVTD 1893

Query: 227  SNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQAL 286
            +NS ST  ++         + +     L   P   L  + T +   L            +
Sbjct: 1894 TNSASTGDTTPLHVTDASSVSTGHATSL---PVTSLSSASTGDTTPLP-----------V 1939

Query: 287  EDKSDAASNSVTETPPTTQPSFTFTLPAAATASPPTSLLAPSTN---PL-LESLKKMQTP 342
               S A+S   T  P T   S        AT+ P T   + ST    PL +     + T 
Sbjct: 1940 TSPSSASSGHTTPLPVTDASSVP---TGHATSLPVTDASSVSTGHATPLPVTDASSVSTG 1996

Query: 343  PSLP-PCPESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLP-------SPSFDSKPPT 394
             + P P  +++  +T +A     TP  +  L  + +G    LP       S   D+  P 
Sbjct: 1997 HATPLPVTDTSSVSTGQA-----TPLPVTSLSSASTGDTTPLPVTDTSSASTGQDTPLPV 2051

Query: 395  TLLGLIPAPSMVPATDTKAPPTLQAETATKPQATSAPSPAPKQSF-LFGTQNTSPSSPAA 453
            T L  +      P   T +P +     AT    T A S +   +  L  T  +S S+  A
Sbjct: 2052 TSLSSVSTGDTTPLPVT-SPSSASTGHATPLLVTDASSVSTGHATSLLVTDASSVSTGHA 2110

Query: 454  PA------ASSASPMFKPIFTAPPKSEKEGPTPPGPSVTATAPSS---SSLPTTTSTTAP 504
             A      +S ++    P+    P S   G T P P    ++ S+   +SLP T +++A 
Sbjct: 2111 TALHVTDASSLSTGDTTPLPVTSPSSASTGDTTPLPVTDTSSVSTGHATSLPVTDTSSAS 2170

Query: 505  TFQ----PVF--SSMGPPASVPLP------APFFKQTTTPATAPTTTAP------LFTGL 546
            T      PV   SS     + PLP      A   + T  P T+P++ +       L T  
Sbjct: 2171 TGHATSLPVTDTSSASTGHATPLPVTDTSSASTGQATPLPVTSPSSASTGHAIPLLVTDT 2230

Query: 547  ASATSAVA---PITSASPSTDSASKPAFGFGINSVSS-----------SSVSTTTSTATA 592
            +SA++  A   P+TS S ++   + P      +SVS+           SSVST  +T   
Sbjct: 2231 SSASTGQATPLPVTSLSSASTGDTTPLPVTDASSVSTGHATSLPVTSLSSVSTGDTTPLP 2290

Query: 593  ASQPFLFGAPQASAASFTPAMGSIFQFGKP-PALPTTTTVTTFSQSLPTAVPTATSSSAA 651
             + P       A+    T A  +      P P    ++  T  +  LP   P++ S+  A
Sbjct: 2291 VTSPSSASTGHATPLHVTDASSASTGHATPLPVTSLSSASTGDTTPLPVTSPSSASTGHA 2350

Query: 652  ------DFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKS-PLP-------S 697
                  D S   +   T  P TSS    +   T  P  +    S+  + PLP       S
Sbjct: 2351 TPLHVTDASSVSTGDTTPLPVTSSSSASSGHTTPLPVTDASSASTGDTTPLPVTDTSSAS 2410

Query: 698  YPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVPA 757
               A   P  G +        +  +T    SS + G+ A P P T+ + A       +P 
Sbjct: 2411 TGHATHLPVTGLSSASTGDTTRLPVTNV--SSASTGH-ATPLPVTSTSSASTGDTTPLP- 2466

Query: 758  HVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAATSSGFGATTQT 817
                       G   S+     T       ASS     G T      + +S+  G TT  
Sbjct: 2467 -----------GTDTSSVSTGHTTPLLVTDASSVST--GDTTRLPVTSPSSASTGHTTPL 2513

Query: 818  ASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATTGAFSFGAGQSGSTAT 877
              + + S+  G TTP P T   S +   + S  ++V +P S++T  A S     + + +T
Sbjct: 2514 PVTDTPSASTGDTTPLPVTNASSLSTRHATS--LHVTSPSSASTGHATSLPVTDTSAAST 2571

Query: 878  STPFTGGLGQNALGTTGQSTPFAFN---VGSTTESKPV-FGGTATPTFGQNTPAPGVGTS 933
                   +   +  +TG +TP         ST ++ P+    T++ + G  TP P   TS
Sbjct: 2572 GHATPLPVTSTSSASTGDTTPLPVTDTYSASTGQATPLPVTDTSSASTGDTTPLPVTDTS 2631

Query: 934  GSSLSFGASSAPAQGFVGVG-----PFGSAAPSFSIGAGSKTP 971
             +S    A+  P      V      P    +PS S   G  TP
Sbjct: 2632 SASTGH-ATPLPVTNTSSVSTGHATPLHVTSPS-SASTGHTTP 2672



 Score = 90.1 bits (222), Expect = 9e-18
 Identities = 188/788 (23%), Positives = 295/788 (37%), Gaps = 132/788 (16%)

Query: 213  GEKAADTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLD 272
            G  + +T P  +  ++S S+  ++     KV  +P+ R    TL    +   S++     
Sbjct: 363  GTVSQETFPSGETTTSSPSSVSNTFLVTSKVFRMPTSRDS--TLGNTEETSLSVSGTISA 420

Query: 273  LEKKASLQWFNQALEDKSDAASNSVTETPPTTQPSF-TFTLPAAATASPP--TSLLAPST 329
            +  K S  W++  L     + + S +  PP    +F T     A T   P   S  +P  
Sbjct: 421  ITSKVSTIWWSDTL-----STALSPSSLPPKISTAFHTQQSEGAETTGRPHERSSFSPGV 475

Query: 330  NPLLESLKKMQTPPS--------------LPPCPESAGAATTEALSPPKTPSL--LP--P 371
            +  + +L +  T PS              LP    S GAAT      P T +   +P  P
Sbjct: 476  SQEIFTLHETTTWPSSFSSKGHTTWSQTELPST--STGAATRLVTGNPSTGTAGTIPRVP 533

Query: 372  LGLSQSGPPGLLPSPSFDSK--PPTTLLG---------------LIPAPS------MVPA 408
              +S  G PG   + S  S   P TT  G               L+ +PS      +  A
Sbjct: 534  SKVSAIGEPGEPTTYSSHSTTLPKTTGAGAQTQWTQETGTTGEALLSSPSYSVTQMIKTA 593

Query: 409  TDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFT 468
            T   + P L   T+   Q T+APS            +TS S   +PA S          T
Sbjct: 594  TSPSSSPMLDRHTSQ--QITTAPSTNHST-----IHSTSTSPQESPAVSQRG------HT 640

Query: 469  APPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQ 528
              P++ +E         + T  S S +  T + T P      S   P   VP  AP    
Sbjct: 641  QAPQTTQE---------SQTTRSVSPMTDTKTVTTPGSSFTASGHSPSEIVPQDAPTISA 691

Query: 529  TTTPATAPT----TTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSS---- 580
             TT A APT    TT    T L +A S+       S  T  +   A     + VS+    
Sbjct: 692  ATTFAPAPTGDGHTTQAPTTALQAAPSSHDATLGPSGGTSLSKTGALTLANSVVSTPGGP 751

Query: 581  ----SSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQ 636
                +S S +TS  TAA+      A    A+  T       Q  +P +  + TT      
Sbjct: 752  EGQWTSASASTSPDTAAAMTHTHQAESTEASGQT-------QTSEPASSGSRTT------ 798

Query: 637  SLPTAVPTATSSSAADFSGFGSTLATSAPAT--SSQPTLTFSNTSTPTFNIPFGSSAKSP 694
            S  TA P+++ +S    SG    ++TS   T  SS P+   S+T+  T  +   S++   
Sbjct: 799  SAGTATPSSSGASGTTPSG-SEGISTSGETTRFSSNPSRD-SHTTQSTTELLSASASHGA 856

Query: 695  LPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPASTIKI 754
            +P         + G A    PG   P L+ +  +    G S+  +P+ +P    A     
Sbjct: 857  IP--------VSTGMASSIVPGTFHPTLSEASTAGRPTGQSSPTSPSASPQETAA----- 903

Query: 755  VPAHVPTPIQPTFGGATHSAFGLKATASAFGAPAS--SQPAFGGSTAVFSFGAATSSGFG 812
            +     T    T  G+   +   +AT +    P +  S  + G ++        + SG G
Sbjct: 904  ISRMAQTQRTRTSRGSDTISLASQATDTFSTVPPTPPSITSTGLTSPQTETHTLSPSGSG 963

Query: 813  ATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATTGAFSFGAGQS 872
             T  TA       +  + TP P T+  SA+   +    +  A+  S+         +  S
Sbjct: 964  KTFTTA-------LISNATPLPVTYASSASTGHTTPLHVTDASSVSTGHATPLPVTSPSS 1016

Query: 873  GSTATSTPFTGGLGQNALGTTGQSTPF---AFNVGSTTESKPV-FGGTATPTFGQNTPAP 928
             ST  +TP    +   +  +TG  TP    +F+  ST +S P+    T++ + G  TP P
Sbjct: 1017 VSTGHTTPLP--VTDTSSESTGHVTPLPVTSFSSASTGDSTPLPVTDTSSASTGHVTPLP 1074

Query: 929  GVGTSGSS 936
                S +S
Sbjct: 1075 VTSLSSAS 1082



 Score = 82.4 bits (202), Expect = 2e-15
 Identities = 219/955 (22%), Positives = 347/955 (36%), Gaps = 121/955 (12%)

Query: 80   SSGSGHSAFEPLVASGVPASFVPKPGSLKRGLNSQSSDDHLNKRSRSSSMSSLTGAYTSG 139
            SS S H+  E      +  SF   P S+   L   S    +   S  S++ +     T+G
Sbjct: 103  SSPSVHNVMETAPPDEMTTSF---PSSVTNTLMMTSKTITMTT-STDSTLGNTEETSTAG 158

Query: 140  IPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRSQTPERPAKKIREEELCH-- 197
              SS+   +TS+ S T G     +     +S   + ASS++    R  +  RE +     
Sbjct: 159  TESST--PVTSAVSITAGQEGQSRTTSWRTSIQDTSASSQNHWT-RSTQTTRESQTSTLT 215

Query: 198  HSSSSTPLAADKESQ--GEKAADTTPRKKQNSNSQ-STPGSSGQRKRKVQLLPS------ 248
            H ++STP  +       G  +  T+P  +  ++S  S   +S     K+ +  S      
Sbjct: 216  HRTTSTPSFSPSVHNVTGTVSQKTSPSGETATSSLCSVTNTSMMTSEKITVTTSTGSTLG 275

Query: 249  RRGEQLTLPPPPQLGYSITAEDL---DLEKKASLQWFNQALEDKSDAASNSVTETPPTTQ 305
              GE  ++P    L   +T+  L   D E ++   +   + +D +  + N  T++  TT+
Sbjct: 276  NPGETSSVPVTGSL-MPVTSAALVTFDPEGQSPATFSRTSTQDTTAFSKNHQTQSVETTR 334

Query: 306  PSFTFTLPAAATASPPTSLLAPS-TNP----LLESLKKMQTPPSLPPCPESAGAATTEAL 360
             S   TL      +  T L +PS  NP      E+    +T  S P    +    T++  
Sbjct: 335  VSQINTLNTLTPVTTSTVLSSPSGFNPSGTVSQETFPSGETTTSSPSSVSNTFLVTSKVF 394

Query: 361  SPP----KTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPT 416
              P     T        LS SG    + S         TL   + +PS +P   + A  T
Sbjct: 395  RMPTSRDSTLGNTEETSLSVSGTISAITSKVSTIWWSDTLSTAL-SPSSLPPKISTAFHT 453

Query: 417  LQ---AETATKPQATSAPSPAPKQS-FLFGTQNTSPSSPAAPAASSASPMFKP------- 465
             Q   AET  +P   S+ SP   Q  F      T PSS ++   ++ S    P       
Sbjct: 454  QQSEGAETTGRPHERSSFSPGVSQEIFTLHETTTWPSSFSSKGHTTWSQTELPSTSTGAA 513

Query: 466  --IFTAPPKSEKEGPTPPGPS----------VTATAPSSSSLPTTTSTTAPTFQPVFSSM 513
              + T  P +   G  P  PS           T  +  S++LP TT   A T     +  
Sbjct: 514  TRLVTGNPSTGTAGTIPRVPSKVSAIGEPGEPTTYSSHSTTLPKTTGAGAQTQWTQETGT 573

Query: 514  GPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGF 573
               A +  P+    Q    AT+P +++P+     S     AP T+ S    +++ P    
Sbjct: 574  TGEALLSSPSYSVTQMIKTATSP-SSSPMLDRHTSQQITTAPSTNHSTIHSTSTSPQESP 632

Query: 574  GINSVSSSSVSTTT--STATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTV 631
             ++    +    TT  S  T +  P        +  S   A G       P   PT +  
Sbjct: 633  AVSQRGHTQAPQTTQESQTTRSVSPMTDTKTVTTPGSSFTASGHSPSEIVPQDAPTISAA 692

Query: 632  TTF----------SQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTP 681
            TTF          +Q+  TA+  A SS  A     G T      + S    LT +N+   
Sbjct: 693  TTFAPAPTGDGHTTQAPTTALQAAPSSHDATLGPSGGT------SLSKTGALTLANSVVS 746

Query: 682  TFNIPFG--SSAKSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPA 739
            T   P G  +SA +       A       A   +  G  + +   S GS  T   +A P+
Sbjct: 747  TPGGPEGQWTSASASTSPDTAAAMTHTHQAESTEASGQTQTSEPASSGSRTTSAGTATPS 806

Query: 740  PATAPTPAPASTIKIV-----------PAHVPTPIQPT----FGGATHSAFGLKATASAF 784
             + A    P+ +  I            P+      Q T       A+H A  +    ++ 
Sbjct: 807  SSGASGTTPSGSEGISTSGETTRFSSNPSRDSHTTQSTTELLSASASHGAIPVSTGMASS 866

Query: 785  GAPASSQPAFG-GSTAVFSFGAATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAP 843
              P +  P     STA    G ++ +   A+ Q  ++ S  +    T  S  +   S A 
Sbjct: 867  IVPGTFHPTLSEASTAGRPTGQSSPTSPSASPQETAAISRMAQTQRTRTSRGSDTISLAS 926

Query: 844  AGSGSFGINVATPGSSATTGAFS----------FGAGQSGSTA---TSTPFTGGLGQNAL 890
              + +F     TP S  +TG  S           G+G++ +TA    +TP       +A 
Sbjct: 927  QATDTFSTVPPTPPSITSTGLTSPQTETHTLSPSGSGKTFTTALISNATPLPVTYASSA- 985

Query: 891  GTTGQSTPFAFNVGSTTESKPVFGGTATP---------TFGQNTPAPGVGTSGSS 936
             +TG +TP        T++  V  G ATP         + G  TP P   TS  S
Sbjct: 986  -STGHTTPL-----HVTDASSVSTGHATPLPVTSPSSVSTGHTTPLPVTDTSSES 1034



 Score = 63.9 bits (154), Expect = 7e-10
 Identities = 150/701 (21%), Positives = 263/701 (37%), Gaps = 86/701 (12%)

Query: 294 SNSVTETPPTTQPSFTFTLPAAATASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAG 353
           + S T  P T+  S T TL   +TA+   +    S   +  S +  QT  +     E+  
Sbjct: 36  TGSKTAAPVTSTGSTTATLEGQSTAASSRT----SNQDISASSQNHQTKST-----ETTS 86

Query: 354 AATTEALSPPKTPSLL--PPL-GLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATD 410
            A T+ L+   T +L   P +  + ++ PP  + + SF S    TL+      +M  +TD
Sbjct: 87  KAQTDTLTQMMTSTLFSSPSVHNVMETAPPDEMTT-SFPSSVTNTLMMTSKTITMTTSTD 145

Query: 411 TKAPPTLQAETA---TKPQATSAPSPAPKQ-------SFLFGTQNTSPSSP--------- 451
           +    T +  TA   +    TSA S    Q       S+    Q+TS SS          
Sbjct: 146 STLGNTEETSTAGTESSTPVTSAVSITAGQEGQSRTTSWRTSIQDTSASSQNHWTRSTQT 205

Query: 452 -------AAPAASSASPMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAP 504
                       ++++P F P       +  +  +P G + T      SSL + T+T+  
Sbjct: 206 TRESQTSTLTHRTTSTPSFSPSVHNVTGTVSQKTSPSGETAT------SSLCSVTNTSMM 259

Query: 505 TFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTD 564
           T + +  +    +++  P        T +  P T+A L T      S   P T +  ST 
Sbjct: 260 TSEKITVTTSTGSTLGNPGETSSVPVTGSLMPVTSAALVTFDPEGQS---PATFSRTSTQ 316

Query: 565 SASKPAFGFGINSVSSSSVS--TTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKP 622
             +  +      SV ++ VS   T +T T  +   +  +P    + F P+ G++ Q   P
Sbjct: 317 DTTAFSKNHQTQSVETTRVSQINTLNTLTPVTTSTVLSSP----SGFNPS-GTVSQETFP 371

Query: 623 PALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTST-- 680
               TT++ ++ S +           ++ D S  G+T  TS   + +   +T S  ST  
Sbjct: 372 SGETTTSSPSSVSNTFLVTSKVFRMPTSRD-STLGNTEETSLSVSGTISAIT-SKVSTIW 429

Query: 681 --PTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQP-------PGAAKPAL----TPSFG 727
              T +     S+  P  S      Q       G+P       PG ++       T ++ 
Sbjct: 430 WSDTLSTALSPSSLPPKISTAFHTQQSEGAETTGRPHERSSFSPGVSQEIFTLHETTTWP 489

Query: 728 SSFTFGNSAAPAPATAPTPAPASTIKIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAP 787
           SSF+       +    P+ +  +  ++V  +  T       G   +   + +  SA G P
Sbjct: 490 SSFSSKGHTTWSQTELPSTSTGAATRLVTGNPST-------GTAGTIPRVPSKVSAIGEP 542

Query: 788 ASSQPAFGGSTAVFSFGAATSSGFGATTQ-TASSGSSSSVFGSTTPSPFTFGGSAAPAGS 846
                    ST +       ++G GA TQ T  +G++     S+     T     A + S
Sbjct: 543 GEPTTYSSHSTTL-----PKTTGAGAQTQWTQETGTTGEALLSSPSYSVTQMIKTATSPS 597

Query: 847 GSFGINVATPGSSATTGAFSFGAGQSGSTA-TSTPFTGGLGQNALGTTGQSTPFAFNVGS 905
            S  ++  T     T  + +     S ST+   +P     G      T Q +    +V  
Sbjct: 598 SSPMLDRHTSQQITTAPSTNHSTIHSTSTSPQESPAVSQRGHTQAPQTTQESQTTRSVSP 657

Query: 906 TTESKPVFGGTATPTFGQNTPAPGVGTSGSSLSFGASSAPA 946
            T++K V    ++ T   ++P+  V     ++S   + APA
Sbjct: 658 MTDTKTVTTPGSSFTASGHSPSEIVPQDAPTISAATTFAPA 698



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 97/465 (20%), Positives = 163/465 (35%), Gaps = 54/465 (11%)

Query: 528 QTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTT 587
           +TT+ A   T T  + + L S+ S    + +A P   + S P+       ++S +++ TT
Sbjct: 83  ETTSKAQTDTLTQMMTSTLFSSPSVHNVMETAPPDEMTTSFPSSVTNTLMMTSKTITMTT 142

Query: 588 STATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATS 647
           ST +      L    + S A            G   + P T+ V+  +     +  T+  
Sbjct: 143 STDST-----LGNTEETSTA------------GTESSTPVTSAVSITAGQEGQSRTTSWR 185

Query: 648 SSAADFSGFGS---TLATSAPATSSQPTLTFSNTSTPTFN--------------IPFGSS 690
           +S  D S       T +T     S   TLT   TSTP+F+               P G +
Sbjct: 186 TSIQDTSASSQNHWTRSTQTTRESQTSTLTHRTTSTPSFSPSVHNVTGTVSQKTSPSGET 245

Query: 691 AKSPLPSYPGANPQ--------PAFGAAEGQPPGAAKPALT----PSFGSSFTFGNSAAP 738
           A S L S    +           + G+  G P   +   +T    P   ++    +    
Sbjct: 246 ATSSLCSVTNTSMMTSEKITVTTSTGSTLGNPGETSSVPVTGSLMPVTSAALVTFDPEGQ 305

Query: 739 APATAPTPAPASTIKIVPAHVPTPIQPTFGGATHSAFGLK--ATASAFGAPASSQPAFGG 796
           +PAT    +   T      H    ++ T     ++   L    T++   +P+   P+   
Sbjct: 306 SPATFSRTSTQDTTAFSKNHQTQSVETTRVSQINTLNTLTPVTTSTVLSSPSGFNPSGTV 365

Query: 797 STAVFSFGAATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATP 856
           S   F  G  T+S   + + T     +S VF   T    T G +   + S S  I+  T 
Sbjct: 366 SQETFPSGETTTSSPSSVSNTFL--VTSKVFRMPTSRDSTLGNTEETSLSVSGTISAITS 423

Query: 857 GSSATTGAFSFGAGQSGSTATSTPFTGGLGQNALGTTGQSTPFAFNVGSTTESKPVFGGT 916
             S    + +     S S+      T    Q + G      P   +  S   S+ +F   
Sbjct: 424 KVSTIWWSDTLSTALSPSSLPPKISTAFHTQQSEGAETTGRPHERSSFSPGVSQEIFTLH 483

Query: 917 ATPTFGQNTPAPGVGTSGS----SLSFGASSAPAQGFVGVGPFGS 957
            T T+  +  + G  T       S S GA++    G    G  G+
Sbjct: 484 ETTTWPSSFSSKGHTTWSQTELPSTSTGAATRLVTGNPSTGTAGT 528


>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
          Length = 5765

 Score =  121 bits (304), Expect = 3e-27
 Identities = 172/655 (26%), Positives = 255/655 (38%), Gaps = 106/655 (16%)

Query: 297  VTETPPTTQPSFTFTLPAAA--TASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGA 354
            +T T  TT  + +   P++   TA PP  L +P+T P   S K   T  S P    +   
Sbjct: 4256 LTTTATTTASTGSTATPSSTPGTAPPPKVLTSPATTPTATSSK--ATSSSSPRTATTLPV 4313

Query: 355  ATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAP 414
             T+ A     T + + P+  S  G  G LP     +  P   +  I   S    T T   
Sbjct: 4314 LTSTATK--STATSVTPIPSSTLGTTGTLPE---QTTTPVATMSTIHPSSTPETTHTSTV 4368

Query: 415  PTLQAETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSE 474
             T +A T     +TS PS  P  +++     T+ ++ AA                     
Sbjct: 4369 LTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAA--------------------- 4407

Query: 475  KEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPAT 534
              GPT    S   T    + L TT +TTA T      S   P+S P        TT   T
Sbjct: 4408 -TGPTATPSSTPGTTWILTELTTTATTTAST-----GSTATPSSTP-------GTTWILT 4454

Query: 535  APTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAAS 594
             P+TTA +   + + ++A A  T A+  T   S  A      +V+SS  + ++S  TA +
Sbjct: 4455 EPSTTATV--TVPTGSTATASSTQATAGTPHVSTTA---TTPTVTSSKATPSSSPGTATA 4509

Query: 595  QPFLFG-APQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADF 653
             P L   A   +A SFT             A+P+++  TT+++   T  PTAT S+A   
Sbjct: 4510 LPALRSTATTPTATSFT-------------AIPSSSLGTTWTRLSQTTTPTATMSTATP- 4555

Query: 654  SGFGSTLATSAPATSSQPTL-TFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEG 712
            S    T+ TS   T++  T     + +TP+       + K P  +  G      F A   
Sbjct: 4556 SSTPETVHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTG------FTATPS 4609

Query: 713  QPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVPAHVPTPIQPTFGGATH 772
              PG    ALTP    S T        P T       ST  + P+ +P        G TH
Sbjct: 4610 SSPGT---ALTPPVWISTT------TTPTTTTPTTSGST--VTPSSIP--------GTTH 4650

Query: 773  SAFGLKATASAFGAPASSQPAFGGSTAVFSFGAATSSGFGATTQTA--SSGSSSSVFGST 830
            +A  L  T +     + + P+    T+    G   S    ATT TA  S+ + SS  G+T
Sbjct: 4651 TARVLTTTTTTVATGSMATPSSSTQTS----GTPPSLTTTATTITATGSTTNPSSTPGTT 4706

Query: 831  TPSPFTFGGSAAPAGSGSFGINVATPGSSATTGAFSFGAGQSGSTATS-TPFTGGL---- 885
              +P     +  PA + S   + ++P ++ T    +  A  + STATS TP         
Sbjct: 4707 PITPVLTSTATTPAATSSKATSSSSPRTATTLPVLTSTA--TKSTATSFTPIPSSTLWTT 4764

Query: 886  ----GQNALGTTGQSTPFAFNVGSTTESKPVFGGTATPTFGQNTPAPGVGTSGSS 936
                 Q     +  ST    +   TT +  V   TAT T   N+ A    T G++
Sbjct: 4765 WTVPAQTTTPMSTMSTIHTSSTPETTHTSTVLTTTATMTRATNSTATPSSTLGTT 4819



 Score =  115 bits (288), Expect = 2e-25
 Identities = 158/629 (25%), Positives = 249/629 (39%), Gaps = 73/629 (11%)

Query: 294  SNSVTETPPTTQPSFTFTLPAAATASPPT----SLLAPSTNPLLESLKKMQTPPSLPPCP 349
            + S T TP +T P  T+ L    TA+  T    S   PS+ P      K+ T  +  P  
Sbjct: 2979 ATSSTATPSST-PGTTWILTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATTPTA 3037

Query: 350  ESAGAATTEALSPPKTPSLLPPLG--LSQSGPPGLLPSPSF----------DSKPPTTLL 397
             S+ A ++   S P+T + LP L    ++S      P PSF           +  P   +
Sbjct: 3038 TSSKATSS---SSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPEQTTTPMATM 3094

Query: 398  GLIPAPSMVPATDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAAS 457
              I   S    T T    T +A T     + S PS  P  +++  T+ T+ ++  A    
Sbjct: 3095 STIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWIL-TELTTAATTTAATGP 3153

Query: 458  SASPMFKPIFT---APPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMG 514
            +A+P   P  T     P +      P G + TA++  +++      T+  T   V SS  
Sbjct: 3154 TATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTPTVISSRA 3213

Query: 515  PPASVPLPA---PFFKQTTTPATAPTTTAPLFTGLASATSAVAPITS--ASPSTDSASKP 569
             P+S P  A   P  + T T  TA + TA   + L +A + ++  T+  A+ ST + S  
Sbjct: 3214 TPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPSST 3273

Query: 570  AFGFGINSVSSSSVSTTTSTATAASQPFLFG------APQASAASF--TPAMGSIFQFGK 621
                  ++V +++ +TT +T + A+     G       P  +   F  TP+         
Sbjct: 3274 PETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTP 3333

Query: 622  PPALPTTTTVTTFSQSL-PTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTF----S 676
            P  + TTTT TT   ++ P+++P  T+ +A   +   +T+AT + AT S  T T     S
Sbjct: 3334 PVWISTTTTPTTRGSTVTPSSIP-GTTHTATVLTTTTTTVATGSMATPSSSTQTSGTPPS 3392

Query: 677  NTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSA 736
             T+T T     GS+      S PG  P P         P A    +TPS         SA
Sbjct: 3393 LTTTATTITATGSTTNP--SSTPGTTPIPPVLTTTATTPAATSSTVTPS---------SA 3441

Query: 737  APAPATAPTPAPASTI--KIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAF 794
                 T P P   +T   + +P   P  ++  +           AT+   G    ++P  
Sbjct: 3442 LGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAW---------TSATSGILGTTHITEP-- 3490

Query: 795  GGSTAVFSFGAATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVA 854
              ST      AAT+S    +T   SS   SS    + PSP    G+  P  +       A
Sbjct: 3491 --STVTSHTPAATTSTTQHSTPALSSPHPSSRTTESPPSP----GTTTPGHTRGTSRTTA 3544

Query: 855  TPGSSATTGAFSFGAGQSGSTATSTPFTG 883
            T   S T  +    +  + +  T+   TG
Sbjct: 3545 TATPSKTRTSTLLPSSPTSAPITTVVTTG 3573



 Score =  106 bits (265), Expect = 9e-23
 Identities = 174/740 (23%), Positives = 253/740 (34%), Gaps = 88/740 (11%)

Query: 290  SDAASNSVTETPPTTQPSFTFTLPAAATASPPTSLLAPSTNPLLESLKKMQTPP---SLP 346
            S A   S   T P  +   T       T+S  T   +P T   L +L+   T P   S+ 
Sbjct: 1925 STATPTSTLRTAPPPKVLTTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSVT 1984

Query: 347  PCPESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTT-LLGLIPAPSM 405
            P P S+   T   LS   TP+         S P     S    +   TT   G +  PS 
Sbjct: 1985 PIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSS 2044

Query: 406  VPAT--DTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMF 463
             P T   TK P T        P ++   +  P       T  T+  S   P++   +   
Sbjct: 2045 TPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHT 2104

Query: 464  KPIFTAPPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPA 523
              + T    +   G      S T T+ +  SL TTT+TT        +    P + P+P 
Sbjct: 2105 ATVLTTTTTTVATGSMATPSSSTQTSGTPPSL-TTTATTITATGSTTNPSSTPGTTPIPP 2163

Query: 524  PFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSAS-------PSTDSASKPAFGFGIN 576
                  TTPA    T  P  + L +  +   P T A+       PS+    + A+    +
Sbjct: 2164 VLTTTATTPAATSNTVTPS-SALGTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATS 2222

Query: 577  SVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTT--VTTF 634
             +  ++  T  ST T+ +     G  Q S  + +    S      PP+  TTT    T  
Sbjct: 2223 GILGTTHITEPSTVTSHTLAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTAT 2282

Query: 635  SQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSP 694
            S++  TA P+ T +S    S   S   T+      +P   +S     ++ +P  S     
Sbjct: 2283 SRTTATATPSKTRTSTLLPSSPTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFD 2342

Query: 695  LPSYPGANPQPAFGAAEGQP----------PGAAKPALTPSFGSSFTFG----------- 733
              S    N + A GA   QP          PG     L      S  FG           
Sbjct: 2343 TYS----NIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGK 2398

Query: 734  ----------------NSAAPAPATAPTPAPASTIKIVPAHVPTPIQPTFGGATHSAFGL 777
                                  PAT+ T  P+ST    P       + T    T  + G 
Sbjct: 2399 FKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSST----PGTTWILTELTTTATTTESTGS 2454

Query: 778  KATASAFGAPASSQPAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSVFGS-----TTP 832
             AT S       S P   G+T + +  + T++    T  TA++ S+ +  G+     T  
Sbjct: 2455 TATPS-------STP---GTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTAT 2504

Query: 833  SPFTFGGSAAPAGSGSFGINVATPGSSATTG-AFSFGAGQSGSTATSTPFTGGLGQNALG 891
            +P      A P  S      +    S+ATT  A SF A  S S  T+      L Q    
Sbjct: 2505 TPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWT---RLSQTTTP 2561

Query: 892  TTGQSTPFAFNVGSTTESKPVFGGTATPTFGQNTPAPGVGTSGSSLSFGASSAPAQGFVG 951
            T   ST    +   T  +  V   TAT T    + A    T G++ +    +    GF  
Sbjct: 2562 TATMSTATPSSTPETVHTSTVLTTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGF-- 2619

Query: 952  VGPFGSAAPSFSIGAGSKTP 971
                 +A PS S G     P
Sbjct: 2620 -----TATPSSSPGTARTLP 2634



 Score =  105 bits (262), Expect = 2e-22
 Identities = 184/762 (24%), Positives = 264/762 (34%), Gaps = 99/762 (12%)

Query: 290  SDAASNSVTETPPTTQPSFTFTLPAAATASPPTSLLAPSTNPLLESLKKMQTPP---SLP 346
            S A ++S   T  T   S T T P   T+S  T   +P T   L +L+   T P   S  
Sbjct: 3740 STATASSTQATAGTPHVSTTATTPTV-TSSKATPFSSPGTATALPALRSTATTPTATSFT 3798

Query: 347  PCPESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTT-LLGLIPAPSM 405
              P S+   T   LS   TP+         S P     S    +   TT   G +  PS 
Sbjct: 3799 AIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRATGSVATPSS 3858

Query: 406  VPAT--DTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMF 463
             P T   TK P T        P ++   +  P       T  T+  S   P++   +   
Sbjct: 3859 TPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPGTTHT 3918

Query: 464  KPIFTAPPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPA 523
              + T    +   G      S T T+ +  SL TT +T   T      S   P + P+P 
Sbjct: 3919 PTVLTTTTTTVATGSMATPSSSTQTSGTPPSLITTATTITATGSTTNPS-STPGTTPIPP 3977

Query: 524  PFFKQTTTPATAPTTTAP------LFTGLASATSAVAPITSASPSTDSASKPAFGFGINS 577
                  TTPA   +T  P        T     T+A     S SPS+    + A+    + 
Sbjct: 3978 VLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSG 4037

Query: 578  VSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTT--VTTFS 635
               ++  T  ST T+ +     G  Q S  + +    S      PP+  TTT    T  S
Sbjct: 4038 TLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATS 4097

Query: 636  QSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPL 695
            ++  TA P+ T +S    S   S   T+   T  +P   +S      ++ P    +    
Sbjct: 4098 RTTATATPSKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWL--DYSYPMPGPSGGDF 4155

Query: 696  PSYPGANPQPAFGAAEGQP----------PGAAKPALTPSFGSSFTFG------------ 733
             +Y  +N + A GA   QP          PG     L      S  FG            
Sbjct: 4156 DTY--SNIRAAGGAVCEQPLGLECRAQAQPGVPLGELGQVVECSLDFGLVCRNREQVGKF 4213

Query: 734  ---------------NSAAPAPATAPTPAPASTIKIVPAHVPTPIQPTFGGATHSAFGLK 778
                                 PAT+ T  P+ST    P       + T    T ++ G  
Sbjct: 4214 KMCFNYEIRVFCCNYGHCPSTPATSSTAMPSST----PGTTWILTELTTTATTTASTGST 4269

Query: 779  ATASAFGAPA---------SSQPAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSVFGS 829
            AT S+    A         ++ P    S A  S    T++     T TA+  +++SV   
Sbjct: 4270 ATPSSTPGTAPPPKVLTSPATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSV--- 4326

Query: 830  TTPSPFTFGG--------SAAPAGSGSFGINVATPGSS-----ATTGAFSFGAGQSGSTA 876
             TP P +  G        +  P  + S     +TP ++      TT A +  A  S ST 
Sbjct: 4327 -TPIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRATSSTSTP 4385

Query: 877  TSTPFTGGLGQNALGTTGQSTPFAFNVGSTTESKP-------VFGGTATPTFGQNTPAPG 929
            +STP T  +      TT  +T  A    +T  S P           TAT T    + A  
Sbjct: 4386 SSTPGTTWILTEL--TTAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATP 4443

Query: 930  VGTSGSSLSFGASSAPAQGFVGVGPFGSAAPSFSIGAGSKTP 971
              T G++      S  A   V   P GS A + S  A + TP
Sbjct: 4444 SSTPGTTWILTEPSTTATVTV---PTGSTATASSTQATAGTP 4482



 Score =  104 bits (259), Expect = 5e-22
 Identities = 173/700 (24%), Positives = 255/700 (36%), Gaps = 78/700 (11%)

Query: 132  LTGAYTSGIPSSSRNAITSSYSSTRGI----SQLWKRNGPSSSPF-SSPASSRSQTPERP 186
            LT   T+   +SS+   +SS  +   +    S   K    S +P  SS   +    PE+ 
Sbjct: 4285 LTSPATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGTLPEQT 4344

Query: 187  AKKIREEELCHHSSSSTPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQRKRKVQLL 246
               +      H   SSTP      +     A TT      S   STPG++          
Sbjct: 4345 TTPVATMSTIH--PSSTPETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAA 4402

Query: 247  PSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETPPTTQP 306
             +      T  P    G +    +L      +    + A    +   +  +TE P TT  
Sbjct: 4403 TTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTTWILTE-PSTTA- 4460

Query: 307  SFTFTLPAAATASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALSPPKTP 366
              T T+P  +TA+  +S  A +  P + +     T  S    P S+          P T 
Sbjct: 4461 --TVTVPTGSTATA-SSTQATAGTPHVSTTATTPTVTSSKATPSSS----------PGTA 4507

Query: 367  SLLPPLGLSQSGPPGL----LPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAETA 422
            + LP L  + + P       +PS S  +          P  +M  AT +  P T+   T 
Sbjct: 4508 TALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTV 4567

Query: 423  TKPQATS--APSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPK---SEKEG 477
                AT+  A       S   GT +T+          +A+P   P     P    S    
Sbjct: 4568 LTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTT 4627

Query: 478  PTPPGPSVTATAPSSSSLPTTTST----TAPTFQPVFSSMGPPASVPLPAPFFKQTTTPA 533
            PT   P+ + +  + SS+P TT T    T  T      SM  P+S    +      TT A
Sbjct: 4628 PTTTTPTTSGSTVTPSSIPGTTHTARVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTA 4687

Query: 534  TAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAA 593
            T  T T    T   S+T    PIT    ST  A+ PA        +SS  ++++S  TA 
Sbjct: 4688 TTITATGS--TTNPSSTPGTTPITPVLTST--ATTPA-------ATSSKATSSSSPRTAT 4736

Query: 594  SQPFLFG-APQASAASFTP---------------------AMGSIFQFGKPPALPTTTTV 631
            + P L   A +++A SFTP                      M +I     P    T+T +
Sbjct: 4737 TLPVLTSTATKSTATSFTPIPSSTLWTTWTVPAQTTTPMSTMSTIHTSSTPETTHTSTVL 4796

Query: 632  TTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQ-PTLTFSNTSTPTFNIPFGSS 690
            TT +        TAT SS    +   + L T+A  T++   T T S+T   T+ +   S+
Sbjct: 4797 TTTATMTRATNSTATPSSTLGTTRILTELTTTATTTAATGSTATLSSTPGTTWILTEPST 4856

Query: 691  -AKSPLPSYPGANPQPAFGAAEGQ---PPGAAKPALTPS-FGSSFTFGNSAAPAPATAPT 745
             A   +P+   A      G A         A  P  T S   SS T G +    PA  P+
Sbjct: 4857 IATVMVPTGSTATASSTLGTAHTPKVVTTMATMPTATASTVPSSSTVGTTR--TPAVLPS 4914

Query: 746  PAPASTIKIVPAHVPTPIQPTFGGATHSAFGLKATASAFG 785
              P  ++  V + V T ++PT  G   S F       AFG
Sbjct: 4915 SLPTFSVSTVSSSVLTTLRPT--GFPSSHFSTPCFCRAFG 4952



 Score =  103 bits (258), Expect = 6e-22
 Identities = 144/542 (26%), Positives = 224/542 (41%), Gaps = 98/542 (18%)

Query: 427  ATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKS-EKEGPTPPGPSV 485
            +T+ PS  P  +++  T+ T+ ++  A   S+A P   P    PPK       TP   S 
Sbjct: 2982 STATPSSTPGTTWIL-TEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATTPTATSS 3040

Query: 486  TATAPSS----SSLPTTTST----TAPTFQPVFS-SMGPPASVPLPAPFFKQTTTPATAP 536
             AT+ SS    ++LP  TST    TA +F P+ S ++G   ++P      +QTTTP    
Sbjct: 3041 KATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLP------EQTTTPMATM 3094

Query: 537  TTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQP 596
            +T  P  T   + TS V  +T+ + +T + S           S S+ S+T  T    ++ 
Sbjct: 3095 STIHPSSTPETTHTSTV--LTTKATTTRATS-----------SMSTPSSTPGTTWILTE- 3140

Query: 597  FLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGF 656
                    +AA+ T A G       P A P++T  TT+  + P+   T T  + +     
Sbjct: 3141 ------LTTAATTTAATG-------PTATPSSTPGTTWILTEPSTTATVTVPTGS----- 3182

Query: 657  GSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPG 716
             +  A+S  AT+    +  S  +TPT      SS  +P  S   A   PA  +    P  
Sbjct: 3183 -TATASSTRATAGTLKVLTSTATTPTVI----SSRATPSSSPGTATALPALRSTATTPTA 3237

Query: 717  AAKPAL-TPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVPAHVPTPIQPTFGGATHSAF 775
             +  A+ + S G+++T  +      AT  T  P+ST + V  H  T +       T +  
Sbjct: 3238 TSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPSSTPETV--HTSTVL-------TTTTT 3288

Query: 776  GLKATASAFGAPASSQPAFGGSTAVFSFGAATSSGFGATTQTA-SSGSSSSVFGSTTPSP 834
              +AT S   A  SS P    +T V      T++GF AT  ++  +  +  V+ STT +P
Sbjct: 3289 TTRATGSV--ATPSSTPGTAHTTKV---PTTTTTGFTATPSSSPGTALTPPVWISTTTTP 3343

Query: 835  FTFGGSAAPAGSGSFGINVATPGSSATTGAFSFGAGQSGSTATSTPFTGGLGQNALGTTG 894
             T G +  P+         + PG++ T    +        T T+T  TG +   +  T  
Sbjct: 3344 TTRGSTVTPS---------SIPGTTHTATVLT--------TTTTTVATGSMATPSSSTQT 3386

Query: 895  QSTPFAFN--------VGSTTESKPVFGGTATP---TFGQNTPAPGVGTSGSSLSFGASS 943
              TP +           GSTT      G T  P   T    TPA    T   S + G + 
Sbjct: 3387 SGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTH 3446

Query: 944  AP 945
             P
Sbjct: 3447 TP 3448



 Score =  102 bits (253), Expect = 2e-21
 Identities = 162/699 (23%), Positives = 263/699 (37%), Gaps = 87/699 (12%)

Query: 316  ATASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATT------EALSPPKTPSLL 369
            AT  PPT+ L  +T    ++L     P S P    +  A+TT      E L+ P+  S  
Sbjct: 1610 ATTPPPTTELETATTTTTQALFSTPQPTSSPGLTRAPPASTTAVPTLSEGLTSPRYTS-- 1667

Query: 370  PPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATD-------TKAPPTLQAET- 421
              LG + +G P   P+ S +   P      +P  S +P T           PPTL   T 
Sbjct: 1668 -TLGTATTGGP-TTPAGSTEPTVPGVATSTLPTRSALPGTTGSLGTWRPSQPPTLAPTTM 1725

Query: 422  -ATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFT-APPKSEKEGPT 479
              ++ + T   S A K+        T  S  +   A +++P  +   +     +  +G T
Sbjct: 1726 ATSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTETTMSPLTNTTTSQGTT 1785

Query: 480  PPGPSVTATAPSSSSLPTT--TSTTAPTFQPVFSSMG----PPASVPLPAPFFKQTTTPA 533
               P    T       PT+        TF+ + ++ G     P S+   A  + + +   
Sbjct: 1786 RCQPKCEWTEWFDVDFPTSGVAGGDMETFENIRAAGGKMCWAPKSIECRAENYPEVSIDQ 1845

Query: 534  TAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSS------SVSTTT 587
                 T  L TGL          T  +          F + +  +         S   T+
Sbjct: 1846 VGQVLTCSLETGL----------TCKNEDQTGRFNMCFNYNVRVLCCDDYSHCPSTPATS 1895

Query: 588  STATAASQP---FLFGAPQASAAS-----FTPAMGSIFQFGKPPALPTTTTVT---TFSQ 636
            STAT +S P   ++   P  +A +      T    S  +   PP + TTT  T   T S+
Sbjct: 1896 STATPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTTTATTPTVTSSK 1955

Query: 637  SLPTAVP-TATSSSAADFSGFGSTLATSAPATSSQPTLTF---SNTSTPTFNIPFGSSAK 692
            + P++ P TAT+  A   +    T  +  P  SS    T+   S T+TPT  +   + + 
Sbjct: 1956 ATPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATPSS 2015

Query: 693  SPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFG------SSFTFGNSAAP--APATAP 744
            +P  ++  +    A     G     A P+ TP         ++ T G +A P  +P TA 
Sbjct: 2016 TPETAHT-STVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTAL 2074

Query: 745  TPAPASTIKIVPAHVPTPIQP-TFGGATHSAFGLKAT----ASAFGAPASSQPAFGGSTA 799
            TP    +    P    + + P +  G TH+A  L  T    A+   A  SS     G+  
Sbjct: 2075 TPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTPP 2134

Query: 800  VFSFGAATSSGFGATTQTASSGSSS---SVFGSTTPSPFTFGGSAAPAGSGSFGINVATP 856
              +  A T +  G+TT  +S+  ++    V  +T  +P     +  P+ +         P
Sbjct: 2135 SLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSNTVTPSSALGTTHTPPVP 2194

Query: 857  GSSATTGAFSFGAGQSGSTATS-TPFTGGLGQNALGTTGQSTP-------FAFNVGSTTE 908
             + ATT   S       +  T+ T  T G+    LGTT  + P        A   G+T  
Sbjct: 2195 NTMATTHGRSLPPSSPHTVRTAWTSATSGI----LGTTHITEPSTVTSHTLAATTGTTQH 2250

Query: 909  SKPVFGGT-ATPTFGQNTPAPGVGTSGSSLSFGASSAPA 946
            S P       +    ++ P+PG  T G + +   ++A A
Sbjct: 2251 STPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATA 2289



 Score =  101 bits (251), Expect = 4e-21
 Identities = 178/732 (24%), Positives = 253/732 (34%), Gaps = 98/732 (13%)

Query: 286  LEDKSDAASNSVTETP-PTTQPSFTFTLPAAATASPPTS--LLAPS-TNPLLESLKKMQT 341
            LE  +   + ++  TP PT+ P  T   PA+ TA P  S  L +P  T+ L  +     T
Sbjct: 1619 LETATTTTTQALFSTPQPTSSPGLTRAPPASTTAVPTLSEGLTSPRYTSTLGTATTGGPT 1678

Query: 342  PPSLPPCPESAGAATTEALSPPKTPSLLPPLGL-SQSGPPGLLPSPSFDSKPPTTLLGLI 400
             P+    P   G AT+   +    P     LG    S PP L P+    S+   T  G  
Sbjct: 1679 TPAGSTEPTVPGVATSTLPTRSALPGTTGSLGTWRPSQPPTLAPTTMATSRARPT--GTA 1736

Query: 401  PAPSMVPATDTKAP------PTLQAETATKPQATSAPSPAPKQSFLFGTQNTSPSS---- 450
               S  P T + AP       T QAET+T P+  +  SP    +   GT    P      
Sbjct: 1737 STASKEPLTTSLAPTLTSELSTSQAETST-PRTETTMSPLTNTTTSQGTTRCQPKCEWTE 1795

Query: 451  ------PAAPAASSASPMFKPIFT-------APPKSEKEGPTPPGPSV-----TATAPSS 492
                  P +  A      F+ I         AP   E      P  S+       T    
Sbjct: 1796 WFDVDFPTSGVAGGDMETFENIRAAGGKMCWAPKSIECRAENYPEVSIDQVGQVLTCSLE 1855

Query: 493  SSLPTTTSTTAPTFQ---------------------PVFSSMGPPASVPLPAPFFKQTTT 531
            + L          F                      P  SS   P+S P        TT 
Sbjct: 1856 TGLTCKNEDQTGRFNMCFNYNVRVLCCDDYSHCPSTPATSSTATPSSTP-------GTTW 1908

Query: 532  PATAPTTTAPLFTGLASATSAVAPITSASPS---TDSASKPAFGFGINSVSSSSVSTTTS 588
              T PTTTA       S  +  + + +A P    T +A+ P       +V+SS  + ++S
Sbjct: 1909 ILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTTTATTP-------TVTSSKATPSSS 1961

Query: 589  TATAASQPFLFG-APQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATS 647
              TA + P L   A   +A S TP   S           TTT   T S + P++ P    
Sbjct: 1962 PGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAH 2021

Query: 648  SSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAF 707
            +S    +   +T AT + AT S    T   T  PT       +  +   + P ++P  A 
Sbjct: 2022 TSTVLTATATTTGATGSVATPSSTPGTAHTTKVPT-------TTTTGFTATPSSSPGTAL 2074

Query: 708  GAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVPAHVPTPIQPTF 767
                  PP       TP+   S T   S+ P      T    +T  +    + TP   T 
Sbjct: 2075 -----TPPVWISTTTTPTTRGS-TVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQ 2128

Query: 768  GGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSVF 827
               T  +    AT        ++  +  G+T +      T++   AT+ T +  S+    
Sbjct: 2129 TSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSNTVTPSSALGT- 2187

Query: 828  GSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATTGAFSFGAGQSGSTATSTPFTGGLGQ 887
              T P P T   +   +   S    V T  +SAT+G          ST TS       G 
Sbjct: 2188 THTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTLAATTGT 2247

Query: 888  NALGTTGQSTPFAFNVGSTTESKPVFGGTATP---TFGQNTPA---PGVGTSGSSLSFGA 941
                T   S+P   +  S T   P   GT TP   T    T A   P    + + L    
Sbjct: 2248 TQHSTPALSSP---HPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSP 2304

Query: 942  SSAPAQGFVGVG 953
            +SAP    V +G
Sbjct: 2305 TSAPITTVVTMG 2316



 Score = 99.0 bits (245), Expect = 2e-20
 Identities = 200/895 (22%), Positives = 313/895 (34%), Gaps = 146/895 (16%)

Query: 135  AYTSGIPSSSRNAITSSYSSTRGIS---QLW-------KRNGPSSSPFSSPASSRSQTPE 184
            A+T+ +P+++    T++ SS+ G +    +W          G + +P S P ++ + T  
Sbjct: 3306 AHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVL 3365

Query: 185  RPAKKIREEELCHHSSSSTPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQRKRKVQ 244
                           SSST  +    S     A T       +N  STPG          
Sbjct: 3366 TTTTTTVATGSMATPSSSTQTSGTPPSL-TTTATTITATGSTTNPSSTPG---------- 3414

Query: 245  LLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETPPTT 304
                      T P PP L  + T                      + +++   T TPP  
Sbjct: 3415 ----------TTPIPPVLTTTATTPAA-------------TSSTVTPSSALGTTHTPPVP 3451

Query: 305  QPSFTFTLPAAATASPPTSLLA--PSTNPLLESLKKMQTPPSLPPCPESAGAATTEALSP 362
              + T    +   +SP T   A   +T+ +L +     T PS       A   +T   S 
Sbjct: 3452 NTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHI--TEPSTVTSHTPAATTSTTQHST 3509

Query: 363  PKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPS----MVPATDTKAPPTLQ 418
            P   S  P    ++S P     +P        T     P+ +    ++P++ T AP T  
Sbjct: 3510 PALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPSKTRTSTLLPSSPTSAPITTV 3569

Query: 419  AETATKPQAT-------SAPSPAPKQSFL-----------------FGTQNTSPSSPAAP 454
              T  +PQ         S P P P                       G +  + + P  P
Sbjct: 3570 VTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVP 3629

Query: 455  AASSASPM------------------FKPIFTAPPK----SEKEGPTPPGPSVTAT---A 489
                   +                  FK  F    +    +    P+ P  S TAT    
Sbjct: 3630 LRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTATPSST 3689

Query: 490  PSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASA 549
            P ++ + T  +TTA T +    S   P+S P        TT   T P+TTA +   + + 
Sbjct: 3690 PGTTWILTKLTTTATTTEST-GSTATPSSTP-------GTTWILTEPSTTATVT--VPTG 3739

Query: 550  TSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFG-APQASAAS 608
            ++A A  T A+  T   S  A      +V+SS  +  +S  TA + P L   A   +A S
Sbjct: 3740 STATASSTQATAGTPHVSTTAT---TPTVTSSKATPFSSPGTATALPALRSTATTPTATS 3796

Query: 609  FTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATS 668
            FT             A+P+++  TT+++   T  PTAT S+A   S   +   ++   T+
Sbjct: 3797 FT-------------AIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTT 3843

Query: 669  SQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGS 728
            +  T    + +TP+       + K P  +  G    P+      + P       T    S
Sbjct: 3844 ATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTS 3903

Query: 729  SFTFGNSAAPAPATAPTPAPASTIKIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPA 788
              T   S+ P     PT    +T  +    + TP   T    T  +    AT        
Sbjct: 3904 GSTVTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLITTATTITATGST 3963

Query: 789  SSQPAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGS 848
            ++  +  G+T +      T++   AT+ T +  S+      T P P T   +   + S S
Sbjct: 3964 TNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGT-THTPPVPNTTATTHGRSLSPS 4022

Query: 849  FGINVATPGSSATTGAFSFGAGQSGSTATSTPFTGGLGQNA--LGTTGQSTP--FAFNVG 904
                V T  +SAT+G         G+T  + P TG     A   GTT  STP   + +  
Sbjct: 4023 SPHTVRTAWTSATSGTL-------GTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPS 4075

Query: 905  STTESKPVFGGTATP---TFGQNTPA---PGVGTSGSSLSFGASSAPAQGFVGVG 953
            S T   P   GT TP   T    T A   P    + + L    +SAP    V  G
Sbjct: 4076 SRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTTG 4130



 Score = 96.7 bits (239), Expect = 1e-19
 Identities = 193/864 (22%), Positives = 305/864 (35%), Gaps = 133/864 (15%)

Query: 127  SSMSSLTGAYTSGIPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRSQTPERP 186
            S+ ++ T    + IPSSS     +  S T   +       PSS+P +             
Sbjct: 1973 STATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPET------------- 2019

Query: 187  AKKIREEELCHHSSSSTPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQRKRKVQLL 246
                        + +ST L A   + G   +  TP         STPG++   K     +
Sbjct: 2020 ------------AHTSTVLTATATTTGATGSVATP--------SSTPGTAHTTK-----V 2054

Query: 247  PSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETPPTTQP 306
            P+      T  P    G ++T             W +      +  ++ + +  P TT  
Sbjct: 2055 PTTTTTGFTATPSSSPGTALTPP----------VWISTTTTPTTRGSTVTPSSIPGTTHT 2104

Query: 307  SFTFTLPAAATASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPE--SAGAATTEALSPPK 364
            +   T      A+   S+  PS+     S +   TPPSL       +A  +TT   S P 
Sbjct: 2105 ATVLTTTTTTVAT--GSMATPSS-----STQTSGTPPSLTTTATTITATGSTTNPSSTPG 2157

Query: 365  TPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAETATK 424
            T  + P L  + +      P+ + ++  P++ LG    P   P  +T A    ++   + 
Sbjct: 2158 TTPIPPVLTTTAT-----TPAATSNTVTPSSALGTTHTP---PVPNTMATTHGRSLPPSS 2209

Query: 425  PQATSAPSPAPKQSFLFGTQNTSPS---SPAAPAASSASPMFKPIFTAPPKSEKEGPTPP 481
            P        +     L  T  T PS   S    A +  +    P  ++P  S +   +PP
Sbjct: 2210 PHTVRTAWTSATSGILGTTHITEPSTVTSHTLAATTGTTQHSTPALSSPHPSSRTTESPP 2269

Query: 482  GPS------------VTATAPSSSSLPTTTSTTAPTFQPVFS--SMGPPA---------- 517
             P              TATA  S +  +T   ++PT  P+ +  +MG             
Sbjct: 2270 SPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTMGCEPQCAWSEWLDY 2329

Query: 518  SVPLPAPFFKQTTT-----PATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFG 572
            S P+P P      T      A       PL     +      P+       +     +  
Sbjct: 2330 SYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVEC----SLD 2385

Query: 573  FGINSVSSSSVSTTTSTATAASQPFL--FGAPQASAASFTPAMGSIFQFGKPPALPTTTT 630
            FG+   +   V           + F   +G   ++ A+ + AM S            TTT
Sbjct: 2386 FGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTTWILTELTTT 2445

Query: 631  VTTFSQSLPTAVPTATSSSAADFSGFGSTLATSAP------ATSSQPTLTFSNTSTPTFN 684
             TT   +  TA P++T  +    +   +T   + P      A+S+Q T    + ST    
Sbjct: 2446 ATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATT 2505

Query: 685  IPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKPAL-TPSFGSSFTFGNSAAPAPATA 743
                SS  +P  S   A   PA  +    P   +  A+ + S G+++T  +      AT 
Sbjct: 2506 PTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATM 2565

Query: 744  PTPAPASTIKIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSF 803
             T  P+ST + V          T  GAT S            A  SS P    +T V + 
Sbjct: 2566 STATPSSTPETVHTSTVLTTTATTTGATGSV-----------ATPSSTPGTAHTTKVLT- 2613

Query: 804  GAATSSGFGAT-TQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATT 862
               T++GF AT + +  +  +  V+ STT +P T G +  P+             ++ TT
Sbjct: 2614 --TTTTGFTATPSSSPGTARTLPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTT 2671

Query: 863  GAFSFGAGQSGSTATS-TPFTGGLGQNALGTTGQSTPFAFNVGSTTESKPVFGGTATPTF 921
             A    A  S ST TS TP +       +  TG +T  +   G TT   PV   TAT   
Sbjct: 2672 VATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPG-TTPIPPVLTTTAT--- 2727

Query: 922  GQNTPAPGVGTSGSSLSFGASSAP 945
               TPA    T   S + G +  P
Sbjct: 2728 ---TPAATSSTVTPSSALGTTHTP 2748



 Score = 94.0 bits (232), Expect = 6e-19
 Identities = 209/873 (23%), Positives = 316/873 (36%), Gaps = 151/873 (17%)

Query: 127  SSMSSLTGAYTSGIPSSSRNAITSSYSSTRGISQLWKRNGPSSSP---FSSPASSRSQTP 183
            S+ ++ T    + IPSSS     +  S T   +       PSS+P    +S   + + T 
Sbjct: 3230 STATTPTATSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTTTT 3289

Query: 184  ERPAKKIREEELCHHSSSSTPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQRKRKV 243
             R    +        + SSTP  A           TT      +   S+PG++      +
Sbjct: 3290 TRATGSVA-------TPSSTPGTAHTTK-----VPTTTTTGFTATPSSSPGTALTPPVWI 3337

Query: 244  QLL--PSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETP 301
                 P+ RG  +T    P   ++ T           L      +   S A  +S T+T 
Sbjct: 3338 STTTTPTTRGSTVTPSSIPGTTHTATV----------LTTTTTTVATGSMATPSSSTQTS 3387

Query: 302  PTTQPSFTFTLPAAATASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALS 361
             T     T      AT S       P T P+         PP L          TT A +
Sbjct: 3388 GTPPSLTTTATTITATGSTTNPSSTPGTTPI---------PPVL----------TTTATT 3428

Query: 362  PPKTPSLLPP---LGLSQSGP-PGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTL 417
            P  T S + P   LG + + P P    +    S PP+       +P  V    T A   +
Sbjct: 3429 PAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLPPS-------SPHTVRTAWTSATSGI 3481

Query: 418  QAET-ATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAP-PKSEK 475
               T  T+P   ++ +PA           TS +  + PA SS  P  +   + P P +  
Sbjct: 3482 LGTTHITEPSTVTSHTPA---------ATTSTTQHSTPALSSPHPSSRTTESPPSPGTTT 3532

Query: 476  EGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFS------------SMGPPASVPLPA 523
             G T      TATA  S +  +T   ++PT  P+ +            S     S P+P 
Sbjct: 3533 PGHTRGTSRTTATATPSKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPG 3592

Query: 524  PFFKQTTT-----PATAPTTTAPLFTGLASATSAVAPITSASPSTDSA------------ 566
            P      T      A       PL     +      P+       + +            
Sbjct: 3593 PSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQ 3652

Query: 567  ---SKPAFGFGI-----NSVSSSSVSTTTSTATAASQP--FLFGAPQASAASFTPAMGSI 616
                K  F + I     N     S   T+STAT +S P          + A+ T + GS 
Sbjct: 3653 VGKFKMCFNYEIRVFCCNYGHCPSTPATSSTATPSSTPGTTWILTKLTTTATTTESTGS- 3711

Query: 617  FQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFS 676
                   A P++T  TT+  + P+   T T  + +      +  A+S  AT+  P ++ +
Sbjct: 3712 ------TATPSSTPGTTWILTEPSTTATVTVPTGS------TATASSTQATAGTPHVS-T 3758

Query: 677  NTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKPAL-TPSFGSSFTFGNS 735
              +TPT      SS  +P  S   A   PA  +    P   +  A+ + S G+++T  + 
Sbjct: 3759 TATTPTVT----SSKATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQ 3814

Query: 736  AAPAPATAPTPAPASTIKIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFG 795
                 AT  T  P+ST +   AH  T +       T +A   +AT S   A  SS P   
Sbjct: 3815 TTTPTATMSTATPSSTPE--TAHTSTVL-------TTTATTTRATGSV--ATPSSTPGTA 3863

Query: 796  GSTAVFSFGAATSSGFGATTQTASSGSSSS--VFGSTTPSPFTFGGSAAPAGSGSFGINV 853
             +T V      T++GF   T ++S G++ +  V+ STT +P T G +  P+         
Sbjct: 3864 HTTKV---PTTTTTGF-TVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPGTTHTP 3919

Query: 854  ATPGSSATTGAFSFGAGQSGSTATS-TPFTGGLGQNALGTTGQSTPFAFNVGSTTESKPV 912
                ++ TT A    A  S ST TS TP +       +  TG +T  +   G TT   PV
Sbjct: 3920 TVLTTTTTTVATGSMATPSSSTQTSGTPPSLITTATTITATGSTTNPSSTPG-TTPIPPV 3978

Query: 913  FGGTATPTFGQNTPAPGVGTSGSSLSFGASSAP 945
               TAT      TPA    T   S + G +  P
Sbjct: 3979 LTTTAT------TPAATSSTVTPSSALGTTHTP 4005



 Score = 92.0 bits (227), Expect = 2e-18
 Identities = 191/776 (24%), Positives = 267/776 (34%), Gaps = 120/776 (15%)

Query: 290  SDAASNSVTETPPTTQPSFTFTLPAAATASPPTSLLAPSTNPLLESLKKMQTPP---SLP 346
            S A ++S   T  T   S T T P   T+S  T   +P T   L +L+   T P   S  
Sbjct: 2483 STATASSTQATAGTPHVSTTATTPTV-TSSKATPFSSPGTATALPALRSTATTPTATSFT 2541

Query: 347  PCPESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTT-LLGLIPAPSM 405
              P S+   T   LS   TP+         S P  +  S    +   TT   G +  PS 
Sbjct: 2542 AIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATTTGATGSVATPSS 2601

Query: 406  VPATDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNTSP---SSPAAPAA--SSAS 460
             P T      T +  T T    T+ PS +P      GT  T P   S+   P    S+ +
Sbjct: 2602 TPGT----AHTTKVLTTTTTGFTATPSSSP------GTARTLPVWISTTTTPTTRGSTVT 2651

Query: 461  PMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSSSLPTTTS-------TTAPTFQPVFSSM 513
            P   P  T  P       T       AT PSSS   T TS       TTA T     S+ 
Sbjct: 2652 PSSIPGTTHTPTVLTTTTTTVATGSMAT-PSSS---TQTSGTPPSLTTTATTITATGSTT 2707

Query: 514  GP---PASVPLPAPFFKQTTTPATAPTTTAP------LFTGLASATSAVAPITSASPSTD 564
             P   P + P+P       TTPA   +T  P        T     T+A     S SPS+ 
Sbjct: 2708 NPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPSSP 2767

Query: 565  SASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPA 624
               + A+    +    ++  T  ST T+ +     G  Q S  + +    S      PP+
Sbjct: 2768 HTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPS 2827

Query: 625  LPTTTTVTT--FSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPT 682
              TTT   T   S++  TA P+ T +S    S   S   T+      +P   +S      
Sbjct: 2828 PGTTTPGHTRATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTMGCEPQCAWSEWL--D 2885

Query: 683  FNIPFGSSAKSPLPSYPGANPQPAFGAAEGQP----------PGAAKPALTPSFGSSFTF 732
            ++ P    +     +Y  +N + A GA   QP          PG     L      S  F
Sbjct: 2886 YSYPMPGPSGGDFDTY--SNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDF 2943

Query: 733  G---------------------------NSAAPAPATAPTPAPASTIKIVPAHVPTPIQP 765
            G                                 PAT+ T  P+ST    P       + 
Sbjct: 2944 GLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTATPSST----PGTTWILTEQ 2999

Query: 766  TFGGATHSAFGLKATASAFGAPASSQP----AFGGSTAVFSFGAATSSGFGATTQT---A 818
            T    T +  G  +TA     P ++ P        +T   +   ATSS    T  T    
Sbjct: 3000 TTAATTTATTG--STAIPSSTPGTAPPPKVLTSTATTPTATSSKATSSSSPRTATTLPVL 3057

Query: 819  SSGSSSSVFGSTTPSP-FTFG-------GSAAPAGSGSFGINVATPGSS-----ATTGAF 865
            +S ++ S   S TP P FT G        +  P  + S     +TP ++      TT A 
Sbjct: 3058 TSTATKSTATSFTPIPSFTLGTTGTLPEQTTTPMATMSTIHPSSTPETTHTSTVLTTKAT 3117

Query: 866  SFGAGQSGSTATSTPFTGGL------GQNALGTTGQSTPFAFNVGST-TESKPVFGGTAT 918
            +  A  S ST +STP T  +             TG +   +   G+T   ++P    T T
Sbjct: 3118 TTRATSSMSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTEPSTTATVT 3177

Query: 919  PTFGQNTPAPGVGTSGSSLSFGASSAPAQGFVGVGPFGSAAPSFSIGAGSKTPGAR 974
               G    A     +  +L    S+A     +       A PS S G  +  P  R
Sbjct: 3178 VPTGSTATASSTRATAGTLKVLTSTATTPTVIS----SRATPSSSPGTATALPALR 3229



 Score = 85.9 bits (211), Expect = 2e-16
 Identities = 124/500 (24%), Positives = 190/500 (38%), Gaps = 80/500 (16%)

Query: 392  PPTTLLGLIPAPSMVPATD-TKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNTSPSS 450
            P T        PS  P T       T  A T     +T+ PS  P  +++     T PS+
Sbjct: 2418 PSTPATSSTAMPSSTPGTTWILTELTTTATTTESTGSTATPSSTPGTTWIL----TEPST 2473

Query: 451  PAAPAASSASPMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVF 510
             A     + S       TA   S +     P  S TAT       PT TS+ A  F    
Sbjct: 2474 TATVTVPTGS-------TATASSTQATAGTPHVSTTATT------PTVTSSKATPFS--- 2517

Query: 511  SSMGPPASVPLPAPFFKQTTTPATAPTTTA-------PLFTGLASATSAVAPITSASPST 563
                P  +  LPA   + T T  TA + TA         +T L+  T+  A +++A+PS+
Sbjct: 2518 ---SPGTATALPA--LRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSS 2572

Query: 564  DSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPP 623
                         +V +S+V TTT+T T A+                   GS+      P
Sbjct: 2573 TP----------ETVHTSTVLTTTATTTGAT-------------------GSVATPSSTP 2603

Query: 624  ALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSS-QPTLTFSNTSTPT 682
                TT V T + +  TA P+++  +A     + ST  T     S+  P+     T TPT
Sbjct: 2604 GTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTPTTRGSTVTPSSIPGTTHTPT 2663

Query: 683  FNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPAT 742
                  ++  +   + P ++ Q       G PP     A T +   S T   + +  P T
Sbjct: 2664 VLTTTTTTVATGSMATPSSSTQ-----TSGTPPSLTTTATTITATGSTT---NPSSTPGT 2715

Query: 743  APTPAPASTIKIVPAHVPTPIQPTFG-GATHSAFGLKATASAFGAPASSQPAFGGSTAVF 801
             P P   +T    PA   + + P+   G TH+      TA+  G   S        TA  
Sbjct: 2716 TPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTA-- 2773

Query: 802  SFGAATSSGFGATTQT-ASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSA 860
             + +ATS   G T  T  S+G+S +   +T  +  +    ++P  S     +  +PG++ 
Sbjct: 2774 -WTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTT 2832

Query: 861  TTGAFSFGAGQSGSTATSTP 880
                       S +TAT+TP
Sbjct: 2833 P----GHTRATSRTTATATP 2848



 Score = 85.9 bits (211), Expect = 2e-16
 Identities = 200/926 (21%), Positives = 314/926 (33%), Gaps = 174/926 (18%)

Query: 127  SSMSSLTGAYTSGIPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRSQTPERP 186
            S+ ++ T    + IPSSS     +  S T   +       PSS+P ++            
Sbjct: 3787 STATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETA------------ 3834

Query: 187  AKKIREEELCHHSSSSTPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQRKRKVQLL 246
                      H S+  T  A    + G  A   TP         STPG++   K      
Sbjct: 3835 ----------HTSTVLTTTATTTRATGSVA---TP--------SSTPGTAHTTK------ 3867

Query: 247  PSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETPPTTQP 306
                     +P     G+++T        +    W +      +  ++ + +  P TT  
Sbjct: 3868 ---------VPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPGTTHT 3918

Query: 307  SFTFTLPAAATASPPTSLLAPSTNPLLESLKKMQTPPSL--PPCPESAGAATTEALSPPK 364
                T      A+   S+  PS+     S +   TPPSL       +A  +TT   S P 
Sbjct: 3919 PTVLTTTTTTVAT--GSMATPSS-----STQTSGTPPSLITTATTITATGSTTNPSSTPG 3971

Query: 365  TPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAETATK 424
            T  + P L  + +      P+ +  +  P++ LG    P   P  +T A    ++ + + 
Sbjct: 3972 TTPIPPVLTTTAT-----TPAATSSTVTPSSALGTTHTP---PVPNTTATTHGRSLSPSS 4023

Query: 425  PQATSAPSPAPKQSFLFGTQNTSPSSPAA--PAASSASPMFK-PIFTAPPKSEKEGPTPP 481
            P        +     L  T  T PS+  +  PAA++ +     P  ++P  S +   +PP
Sbjct: 4024 PHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPP 4083

Query: 482  GPS------------VTATAPSSSSLPTTTSTTAPTFQPVFS------------SMGPPA 517
             P              TATA  S +  +T   ++PT  P+ +            S     
Sbjct: 4084 SPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWLDY 4143

Query: 518  SVPLPAPFFKQTTT-----PATAPTTTAPLFTGLASATSAVAPITSASPSTDSA------ 566
            S P+P P      T      A       PL     +      P+       + +      
Sbjct: 4144 SYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLGELGQVVECSLDFGLV 4203

Query: 567  ---------SKPAFGFGI-----NSVSSSSVSTTTSTATAASQP--FLFGAPQASAASFT 610
                      K  F + I     N     S   T+STA  +S P          + A+ T
Sbjct: 4204 CRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTT 4263

Query: 611  PAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQ 670
             + GS       P       V T     P   PTATSS A   S      AT+ P  +S 
Sbjct: 4264 ASTGSTATPSSTPGTAPPPKVLT----SPATTPTATSSKAT--SSSSPRTATTLPVLTST 4317

Query: 671  PTLTFSNTSTPTFNIPFGSSAKSPLPS----------YPGANPQPAFGA----AEGQPPG 716
             T + + + TP  +   G++   P  +          +P + P+    +     +     
Sbjct: 4318 ATKSTATSVTPIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTR 4377

Query: 717  AAKPALTPSFGSSFTF-----GNSAAPAPATAPTPAPASTIKIVPAHVPTPIQPTFGGAT 771
            A     TPS     T+       +A    AT PT  P+ST    P       + T    T
Sbjct: 4378 ATSSTSTPSSTPGTTWILTELTTAATTTAATGPTATPSST----PGTTWILTELTTTATT 4433

Query: 772  HSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSVFG--- 828
             ++ G  AT        SS P   G+T + +  + T++    T  TA++ S+ +  G   
Sbjct: 4434 TASTGSTAT-------PSSTP---GTTWILTEPSTTATVTVPTGSTATASSTQATAGTPH 4483

Query: 829  --STTPSPFTFGGSAAPAGSGSFGINVATPGSSATT-GAFSFGAGQSGSTATSTPFTGGL 885
              +T  +P      A P+ S      +    S+ATT  A SF A  S S  T+      L
Sbjct: 4484 VSTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWT---RL 4540

Query: 886  GQNALGTTGQSTPFAFNVGSTTESKPVFGGTATPTFGQNTPAPGVGTSGSSLSFGASSAP 945
             Q    T   ST    +   T  +  V   TAT T    + A    T G++ +    +  
Sbjct: 4541 SQTTTPTATMSTATPSSTPETVHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTT 4600

Query: 946  AQGFVGVGPFGSAAPSFSIGAGSKTP 971
              GF       +A PS S G     P
Sbjct: 4601 TTGF-------TATPSSSPGTALTPP 4619



 Score = 85.5 bits (210), Expect = 2e-16
 Identities = 122/515 (23%), Positives = 197/515 (38%), Gaps = 93/515 (18%)

Query: 427  ATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFT---APPKSEKEGPTPPGP 483
            +T+ PS  P  +++  T+ T+ ++      S+A+P   P  T     P +      P G 
Sbjct: 2425 STAMPSSTPGTTWIL-TELTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTGS 2483

Query: 484  SVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTA--- 540
            + TA++  +++     STTA T   V SS   P S P  A       + AT PT T+   
Sbjct: 2484 TATASSTQATAGTPHVSTTATT-PTVTSSKATPFSSPGTATALPALRSTATTPTATSFTA 2542

Query: 541  -------PLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAA 593
                     +T L+  T+  A +++A+PS+             +V +S+V TTT+T T A
Sbjct: 2543 IPSSSLGTTWTRLSQTTTPTATMSTATPSSTP----------ETVHTSTVLTTTATTTGA 2592

Query: 594  SQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADF 653
            +                   GS+      P    TT V T + +  TA P+++  +A   
Sbjct: 2593 T-------------------GSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTL 2633

Query: 654  SGFGSTLATSAPATSS-QPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEG 712
              + ST  T     S+  P+     T TPT      ++  +   + P ++ Q +     G
Sbjct: 2634 PVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTS-----G 2688

Query: 713  QPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVPAHVPTPIQPTFG-GAT 771
             PP     A T +   S T  +S    P T P P   +T    PA   + + P+   G T
Sbjct: 2689 TPPSLTTTATTITATGSTTNPSST---PGTTPIPPVLTTTATTPAATSSTVTPSSALGTT 2745

Query: 772  HSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSVFGSTT 831
            H+                  P    +TA  + G + S     T +TA + ++S   G+T 
Sbjct: 2746 HT------------------PPVPNTTAT-THGRSLSPSSPHTVRTAWTSATSGTLGTTH 2786

Query: 832  PSPFTFGGSAAPAGSGSFGINVATPGSSATTGAFSFGAGQSGSTATSTPFTGGLGQNALG 891
             +  + G S  PA               ATT     G  Q  + A S+P        +  
Sbjct: 2787 ITEPSTGTSHTPA---------------ATT-----GTTQHSTPALSSPHPSSRTTESPP 2826

Query: 892  TTGQSTPFAFNVGSTTESKPVFGGTATPTFGQNTP 926
            + G +TP      S T +      T T T   ++P
Sbjct: 2827 SPGTTTPGHTRATSRTTATATPSKTRTSTLLPSSP 2861



 Score = 80.1 bits (196), Expect = 9e-15
 Identities = 176/782 (22%), Positives = 266/782 (34%), Gaps = 169/782 (21%)

Query: 313  PAAATASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALSPPKTPSLLPPL 372
            PA ++ + P+S   P T  +L  L              +  A TTE+     TPS  P  
Sbjct: 2421 PATSSTAMPSS--TPGTTWILTEL--------------TTTATTTESTGSTATPSSTP-- 2462

Query: 373  GLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPP-------TLQAETATKP 425
                 G   +L  PS      TT    +P  S   A+ T+A         T    T T  
Sbjct: 2463 -----GTTWILTEPS------TTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSS 2511

Query: 426  QATSAPSPAPKQSF----LFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPP 481
            +AT   SP    +        T  T+ S  A P++S  +   +   T  P +     TP 
Sbjct: 2512 KATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPS 2571

Query: 482  GPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTAP 541
              S   T  +S+ L TT +TT  T      S+  P+S P  A   K  TT  T  T T  
Sbjct: 2572 --STPETVHTSTVLTTTATTTGAT-----GSVATPSSTPGTAHTTKVLTTTTTGFTATPS 2624

Query: 542  LFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAA-SQPFLFG 600
               G A         T+   +  S   P+   G     +   +TTT+ AT + + P    
Sbjct: 2625 SSPGTARTLPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSMATPSSST 2684

Query: 601  APQASAASFTPAMGSIFQFG---KPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFG 657
                +  S T    +I   G    P + P TT +     +  T  P ATSS+    S  G
Sbjct: 2685 QTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTAT-TPAATSSTVTPSSALG 2743

Query: 658  STLATSAPATS----------SQP----------------TLTFSNTSTPTFNIPFGSSA 691
            +T     P T+          S P                T   +  ST T + P  ++ 
Sbjct: 2744 TTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTG 2803

Query: 692  KSPLPSYPGANPQPAFGAAEGQP-PGAAKPALTPSFGSSFTFGNSAAPAPAT----APTP 746
             +   +   ++P P+    E  P PG   P  T +   +      +    +T    +PT 
Sbjct: 2804 TTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRATSRTTATATPSKTRTSTLLPSSPTS 2863

Query: 747  APASTIKIVPAH--------------VPTP----------IQPTFGGATHSAFGLKATAS 782
            AP +T+  +                 +P P          I+   G       GL+  A 
Sbjct: 2864 APITTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQ 2923

Query: 783  A------------------FGAPASSQPAFGGSTAVFSFGAAT-SSGFG---ATTQTASS 820
            A                  FG    ++   G     F++        +G   +T  T+S+
Sbjct: 2924 AQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSST 2983

Query: 821  GSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPG---------SSATTGAFSFGAGQ 871
             + SS  G+T         +   A +GS  I  +TPG         S+ATT   +     
Sbjct: 2984 ATPSSTPGTTWILTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATTPTATSSKAT 3043

Query: 872  SGST----------------ATSTPFTGGLGQNALGTTG-----QSTPFA-------FNV 903
            S S+                +T+T FT  +    LGTTG      +TP A        + 
Sbjct: 3044 SSSSPRTATTLPVLTSTATKSTATSFT-PIPSFTLGTTGTLPEQTTTPMATMSTIHPSST 3102

Query: 904  GSTTESKPVFGGTATPTFGQNTPAPGVGTSGSSLSFGASSAPAQGFVGVGPFGSAAPSFS 963
              TT +  V    AT T   ++ +    T G++      +  A      GP  +A PS +
Sbjct: 3103 PETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATTTAATGP--TATPSST 3160

Query: 964  IG 965
             G
Sbjct: 3161 PG 3162



 Score = 79.7 bits (195), Expect = 1e-14
 Identities = 188/880 (21%), Positives = 299/880 (33%), Gaps = 165/880 (18%)

Query: 167  PSSSPFSSPASSRSQTPERPAKKIREEELCHHSSSSTPLAADKESQGEKAADTTPRKKQN 226
            P++S  ++P+S+   T                 S++TP +  + +   K   TT      
Sbjct: 1892 PATSSTATPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTTTATTPTV 1951

Query: 227  SNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQAL 286
            ++S++TP SS              G    LP       + TA  +     +SL      L
Sbjct: 1952 TSSKATPSSSP-------------GTATALPALRSTATTPTATSVTPIPSSSLGTTWTRL 1998

Query: 287  EDKSDAASNSVTETP---PTTQPSFTFTLPAAATASPPTSLLAPSTNPLLESLKKMQTPP 343
               +   +   T TP   P T  + T     A T     S+  PS+ P      K+    
Sbjct: 1999 SQTTTPTATMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKV---- 2054

Query: 344  SLPPCPESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAP 403
               P   + G   T + SP    +L PP+ +S +  P              T  G    P
Sbjct: 2055 ---PTTTTTGFTATPSSSPGT--ALTPPVWISTTTTP--------------TTRGSTVTP 2095

Query: 404  SMVPATD------TKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAAS 457
            S +P T       T    T+   +   P +++  S  P       T  T+  S   P+++
Sbjct: 2096 SSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSST 2155

Query: 458  SASPMFKPIFTAP---PKSEKEGPTPPGP-SVTATAPSSSSLPTTTSTTAPTFQP--VFS 511
              +    P+ T     P +     TP      T T P  +++ TT   + P   P  V +
Sbjct: 2156 PGTTPIPPVLTTTATTPAATSNTVTPSSALGTTHTPPVPNTMATTHGRSLPPSSPHTVRT 2215

Query: 512  SMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLAS-ATSAVAPITSASPSTDSASKPA 570
            +     S  L        T P+T  + T    TG    +T A++    +S +T+S   P 
Sbjct: 2216 AWTSATSGILGT---THITEPSTVTSHTLAATTGTTQHSTPALSSPHPSSRTTESPPSP- 2271

Query: 571  FGFGINSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTT 630
                    ++   +T TS  TA + P      +   ++  P+         P + P TT 
Sbjct: 2272 ------GTTTPGHTTATSRTTATATP-----SKTRTSTLLPS--------SPTSAPITTV 2312

Query: 631  VT-------TFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQP------------ 671
            VT        +S+ L  + P     S  DF  + S +  +  A   QP            
Sbjct: 2313 VTMGCEPQCAWSEWLDYSYP-MPGPSGGDFDTY-SNIRAAGGAVCEQPLGLECRAQAQPG 2370

Query: 672  ------------TLTFS----------------NTSTPTFNIPFGSSAKSPLPS---YPG 700
                        +L F                 N     F   +G    +P  S    P 
Sbjct: 2371 VPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPS 2430

Query: 701  ANPQPAFGAAE--------GQPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPASTI 752
            + P   +   E              A P+ TP  G+++     +  A  T PT + A+  
Sbjct: 2431 STPGTTWILTELTTTATTTESTGSTATPSSTP--GTTWILTEPSTTATVTVPTGSTATAS 2488

Query: 753  KI-----VPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAAT 807
                    P    T   PT   +  + F    TA+A  A  S+      +    SF A  
Sbjct: 2489 STQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRST----ATTPTATSFTAIP 2544

Query: 808  SSGFGAT-TQTASSGSSSSVFGSTTPS--PFTFGGS-------AAPAGSGSFGINVATPG 857
            SS  G T T+ + + + ++   + TPS  P T   S            +GS     +TPG
Sbjct: 2545 SSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATTTGATGSVATPSSTPG 2604

Query: 858  SSATTGAFS-----FGAGQSGSTATSTPFTGGLGQNALGTTGQSTPFAFNVGSTTESKPV 912
            ++ TT   +     F A  S S  T+      +      TT  ST    ++  TT +  V
Sbjct: 2605 TAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTPTTRGSTVTPSSIPGTTHTPTV 2664

Query: 913  FGGTAT--PTFGQNTPAPGVGTSGS--SLSFGASSAPAQG 948
               T T   T    TP+    TSG+  SL+  A++  A G
Sbjct: 2665 LTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATG 2704



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 119/491 (24%), Positives = 165/491 (33%), Gaps = 77/491 (15%)

Query: 529  TTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTS 588
            TT   TA TTT          TS+  P  + +P   + + P    G+ S   +S   T +
Sbjct: 1616 TTELETATTTTTQALFSTPQPTSS--PGLTRAPPASTTAVPTLSEGLTSPRYTSTLGTAT 1673

Query: 589  TATAASQPFLFGAPQASAASFTPAMGSIFQFGKPP--ALPTTT-TVTTFSQSLP-TAVPT 644
            T          G P   A S  P +  +     P   ALP TT ++ T+  S P T  PT
Sbjct: 1674 T----------GGPTTPAGSTEPTVPGVATSTLPTRSALPGTTGSLGTWRPSQPPTLAPT 1723

Query: 645  ATSSSAADFSGFGSTLATSAPATSSQPTLTFS-NTSTPTFNIPFGSSAKSPLPSYPGANP 703
              ++S A  +G  ST +     TS  PTLT   +TS    + P   +  SPL      N 
Sbjct: 1724 TMATSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTETTMSPL-----TNT 1778

Query: 704  QPAFGAAEGQPP-------GAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVP 756
              + G    QP            P    + G   TF N  A        P    +I+   
Sbjct: 1779 TTSQGTTRCQPKCEWTEWFDVDFPTSGVAGGDMETFENIRAAGGKMCWAP---KSIECRA 1835

Query: 757  AHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFG--------------GSTAVFS 802
             + P       G     +     T             F                ST   S
Sbjct: 1836 ENYPEVSIDQVGQVLTCSLETGLTCKNEDQTGRFNMCFNYNVRVLCCDDYSHCPSTPATS 1895

Query: 803  FGAATSSGFGAT----------TQTASSGSSSSVFGS--TTPSPFTFGGSAA-PAGSGSF 849
              A  SS  G T          T TAS+GS+++   +  T P P     +A  P  + S 
Sbjct: 1896 STATPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTTTATTPTVTSSK 1955

Query: 850  GINVATPGSSATTGAFSFGAGQSGSTATS-TPFTGG--------LGQNALGTTGQSTPFA 900
                ++PG++    A    A  +  TATS TP            L Q    T   ST   
Sbjct: 1956 ATPSSSPGTATALPALRSTA--TTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATP 2013

Query: 901  FNVGSTTESKPVFGGTATPTFGQNTPAPGVGTSGSSLSFGASSAPAQGFVGVGPFGSAAP 960
             +   T  +  V   TAT T    + A    T G++ +    +    GF       +A P
Sbjct: 2014 SSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGF-------TATP 2066

Query: 961  SFSIGAGSKTP 971
            S S G     P
Sbjct: 2067 SSSPGTALTPP 2077


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score =  121 bits (303), Expect = 4e-27
 Identities = 202/900 (22%), Positives = 347/900 (38%), Gaps = 136/900 (15%)

Query: 130 SSLTGAYTSGIPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRSQTPERPAKK 189
           +SLT       P ++    +SS ++    +     N   S+P +S  +S  +     A  
Sbjct: 176 TSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASSEAIT 235

Query: 190 IREEELCHHSSSSTPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSR 249
           +    L      STP+    ++    ++ TT      SNS  + GS+   +  + ++   
Sbjct: 236 L----LTTPVEISTPVTISAQAS---SSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVV 288

Query: 250 RGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETPPTTQPSFT 309
             E  TL   P       A ++ +                S  AS+S T    T+ P+ T
Sbjct: 289 SSEASTLSTTP------AATNIPVIT--------------STEASSSPTTAEGTSIPTST 328

Query: 310 FTLPAAATASPPTSLLAPSTNPL---------LESLKKMQTPPSLPPCPESAGAATTEAL 360
           +T  +    S P S +  +T+ +           +L    T PS  P    A +  T  L
Sbjct: 329 YTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTL 388

Query: 361 SPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAE 420
           S   TP                       + P +T+L      S   +T +  P   +  
Sbjct: 389 SEGSTP---------------------LTNMPVSTIL----VASSEASTTSTIPVDSKTF 423

Query: 421 TATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEG--- 477
             T  +A+S+P+ A   S    T    PS  + P  S       P+ T P  S +     
Sbjct: 424 VTTASEASSSPTTAEDTSIATST----PSEGSTPLTS------MPVSTTPVASSEASNLS 473

Query: 478 --PTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASV---PLPAPFFKQTTTP 532
             P      VT +  +SSS PT    + PT  P   S  P  S+    +P    + +T  
Sbjct: 474 TTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGST-PLTSMSVSTMPVASSEASTLS 532

Query: 533 ATAPTTTAPLFTGLASATSAVAPITSASPST--DSASKPAFGFGINS-VSSSSVSTTTST 589
            T   T+ P+ T   +++S+  P  ++ P++     S P     +++ +  SS ++TTST
Sbjct: 533 TTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTST 592

Query: 590 ATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSS 649
             A S  F+  + +AS++S T A G+           TT T  + S +L  +   +T S+
Sbjct: 593 TPADSNTFVTTSSEASSSS-TTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLST 651

Query: 650 AADFSGFGSTLATSAPATS------SQPTLTFSNTSTPTFNIP-----FGSSAKSPLPSY 698
               S    T +T A ++S      S PT T++  STP  ++P       SS  S L + 
Sbjct: 652 TPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTT 711

Query: 699 PGANPQPAFGAAEGQ-----PPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPASTIK 753
           P     P   + E         GA+ P  TPS GS+     ++ P   T  T + AST+ 
Sbjct: 712 PVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGST---PLTSMPVSKTLLTSSEASTLS 768

Query: 754 IVP----AHVPTPIQPTFGGATHSAFGLKATASAFGAP------------ASSQPAFGGS 797
             P     H+ T  + +    T     +  +  + G+P             S + +   +
Sbjct: 769 TTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLST 828

Query: 798 TAVFSFGAATSSGFGATTQTASSGSS--SSVFG------STTPSPFTFGGSAAPAGSGSF 849
           T V S    T+S   +++ T + G+S  +S +       ++ P   T   ++A +   + 
Sbjct: 829 TPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTT 888

Query: 850 GINVATPGSSATTGAFSFGAGQSGSTATSTPFTGGLGQNALGTTGQSTPFAFNVGSTTES 909
            ++ +TP +++T    S    +  S  TSTP  G     ++     +TP   +   T  +
Sbjct: 889 PVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSM--PDSTTPVVSSEARTLSA 946

Query: 910 KPVFGGTATPTFGQNTPAPGVGTSGSSLSFGASSAPAQGFVGVGPFGSAAPSFSIGAGSK 969
            PV   T   T  + T +P     G+S+    +S P++   G  P  S   S ++ A S+
Sbjct: 947 TPVDTSTPVTTSTEATSSP-TTAEGTSI---PTSTPSE---GTTPLTSTPVSHTLVANSE 999



 Score =  118 bits (295), Expect = 3e-26
 Identities = 213/898 (23%), Positives = 335/898 (37%), Gaps = 144/898 (16%)

Query: 94   SGVPASFVPKPGSLKRGLNSQSSDDHLNKRSRSSSMSSLTGAYTSGIPSSSRNAITSSYS 153
            + +P S  P   S  R L++   D      + + + SS T A  + IP+S+ +  T+  +
Sbjct: 927  TSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLT 986

Query: 154  STRGISQLWKRNGPSSSPFSSPASSRSQTPERPAKKIREEELCHHSSSSTPLAADKESQG 213
            ST  +S     N        S AS+ S TP                 S+TPL    E   
Sbjct: 987  STP-VSHTLVAN--------SEASTLSTTPV---------------DSNTPLTTSTE--- 1019

Query: 214  EKAADTTPRKKQNSNSQSTP--GSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDL 271
              A+   P  +  S   STP  GS+   +  V        E  TL   P    + T+  +
Sbjct: 1020 --ASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTP----ADTSTPV 1073

Query: 272  DLEKKASLQWFNQALEDKSDAASNSVTE--TPPTTQPSFTFTLPAAATASPPTSLLAPST 329
                +AS    +    D +   +++ +E  TP T+ P  T  L  ++ AS  ++    ++
Sbjct: 1074 TTYSQASS---SSTTADGTSMPTSTYSEGSTPLTSVPVST-RLVVSSEASTLSTTPVDTS 1129

Query: 330  NPLLESLKKMQTPP-----SLPPCPESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLP 384
             P+  S +   +P      S+P  P S G  TT   S P + +L+       S     L 
Sbjct: 1130 IPVTTSTEASSSPTTAEGTSIPTSPPSEG--TTPLASMPVSTTLVV------SSEANTLS 1181

Query: 385  SPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQ 444
            +   DSK  T +     A S  P  +  + PT      + P  +      P  S    T 
Sbjct: 1182 TTPVDSK--TQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTL 1239

Query: 445  NTSPSSPAAPAASSASPMFKPIF----TAPPKSEKEGPTP----PGPSVTATAPSSSSLP 496
            +TSP   + P  +SA     P      + P  +  EG T     P  +   T+P +S+L 
Sbjct: 1240 STSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLL 1299

Query: 497  TT---TSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAV 553
            TT   T     T   V SS  P     +P   + +  TP T+      L    A +  + 
Sbjct: 1300 TTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILST 1359

Query: 554  APITSASP---STDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQASAASFT 610
             P+ +++P   ST++ S P    G +  +S+    TT   +         + +AS  S T
Sbjct: 1360 TPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSAT 1419

Query: 611  PAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQ 670
            P             + T+T  TT +++  T+ PT            G ++ TS P+    
Sbjct: 1420 P-------------VDTSTPGTTSAEA--TSSPTTAE---------GISIPTSTPSEGKT 1455

Query: 671  PTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSF 730
            P  +   ++TP  N    + + +P+ S        A  ++     G +    TPS GS+ 
Sbjct: 1456 PLKSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGST- 1514

Query: 731  TFGNSAAPAPATAPTPAPASTIKIVPAHVPTPIQPTFGGATHS---AFGLKATASAFG-- 785
                ++ P   T    +  +++   PA   TP+  T+  A+ S   A G     S +   
Sbjct: 1515 --ALTSIPVSTTTVASSEINSLSTTPAVTSTPV-TTYSQASSSPTTADGTSMQTSTYSEG 1571

Query: 786  ------------------------APASSQPAFGGSTAVFSFGAATSSGFGATTQTASSG 821
                                     P  S+     ST   S  + T+ G   T  T S G
Sbjct: 1572 STPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASS--STTAEGSSMTISTPSEG 1629

Query: 822  SS--SSVFGSTTP--SPFTFGGSAAPAGSGSFGINVATPGSSATTGAFSFGAGQSGSTAT 877
            S   +S+  STTP  SP     S  P  S S  +  +T  SS+ T A       S  T  
Sbjct: 1630 SPLLTSIPVSTTPVASPEASTLSTTPVDSNS-PVITSTEVSSSPTPAEGTSMPTSTYTEG 1688

Query: 878  STPFTGGLGQNALGTTGQSTPFAFNVGSTTESKPVFGGT--ATPTFGQNTPAPGVGTS 933
             TP T          T ++TP A +  ST  + PV   T   T T  +++P    GTS
Sbjct: 1689 RTPLT--------SITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTS 1738



 Score =  117 bits (293), Expect = 5e-26
 Identities = 205/918 (22%), Positives = 341/918 (37%), Gaps = 131/918 (14%)

Query: 126  SSSMSSLTGAYTSGIPSSSRNAITSSYS----STRGISQLWKRNGPSSSPFSSPASSRSQ 181
            S   + LT    S  P  S  A T S +    ST G +     + P+++   S  +S   
Sbjct: 1392 SEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPS 1451

Query: 182  TPERPAKKIREEELCHHSSSSTPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQRKR 241
              + P K I          S+TP+A  + S       TTP    +    ST  SS     
Sbjct: 1452 EGKTPLKSI--------PVSNTPVANSEAS----TLSTTPVDSNSPVVTSTAVSSSPTPA 1499

Query: 242  KVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETP 301
            +        G  + +  P +   ++T+  +     AS        E  S + + +VT TP
Sbjct: 1500 E--------GTSIAISTPSEGSTALTSIPVSTTTVASS-------EINSLSTTPAVTSTP 1544

Query: 302  PTTQPSFTFTLPAAATASPPTSLLAPSTNPL--------LESLKKMQTPPSLPPCPESAG 353
             TT    + +   A   S  TS  +  + PL        L    +  T  + P   ++  
Sbjct: 1545 VTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQV 1604

Query: 354  AATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDS---KPPTTLLGLIPAPSMVP--- 407
             A+TEA S          +     G P L   P   +    P  + L   P  S  P   
Sbjct: 1605 TASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVIT 1664

Query: 408  ATDTKAPPTLQAETATKPQATSAPSPAPKQSFL----------FGTQNTSPSSPAAPAAS 457
            +T+  + PT  AE  + P +T      P  S              T +T+P   + P  +
Sbjct: 1665 STEVSSSPT-PAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTT 1723

Query: 458  S----ASPMFKPIFTAPPKSEKEGPTP-------PGPSVTATAPSSSSLPTTTSTTAPTF 506
            S    +SP      + P  +  EG TP         P +++ A + S+ P  TST   T 
Sbjct: 1724 STEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTS 1783

Query: 507  QPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASP---ST 563
                SS        +P     +  TP T+   +  L     ++T +  P+ S SP   ST
Sbjct: 1784 TEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTST 1843

Query: 564  DSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGS--IFQFGK 621
              +S P    G +  +S+    +T+  +         + + +  S TPA+ S  +  + +
Sbjct: 1844 AVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQ 1903

Query: 622  PPALPTTTTVTTFSQSLP-------TAVPTATSS-SAADFSGFGSTL------------A 661
              + PTT   ++   S P       T++P +T++ ++++ +   +TL            A
Sbjct: 1904 VSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQA 1963

Query: 662  TSAPAT---SSQPTLTFSNTSTPTFNIPFG-----SSAKSPLPSYPGANPQPAFGAAEG- 712
            +S+P T   +S PT  +S  STP  ++P       SS  S L + P     PA  + EG 
Sbjct: 1964 SSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGS 2023

Query: 713  -QPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVPAHVPTPI-QPTFGGA 770
              P  A   ++  S  S  T   +  P   T    +  +T+   P    T +   T   +
Sbjct: 2024 SSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASS 2083

Query: 771  THSAFGLKATASA--------FGAPASSQPAFGGSTAVFSFGAATSSGFGATTQTASS-- 820
            + +A G   T SA           P S+ P      +  S     S+    T+   SS  
Sbjct: 2084 SATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSP 2143

Query: 821  ----GSS--SSVFG------STTPSPFTFGGSAAPAGSGSFGINVATPGSSATTGAFSFG 868
                G+S  +S +       ++ P   T   S+A +   +  ++ +TP +++T    S  
Sbjct: 2144 IPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPT 2203

Query: 869  AGQSGSTATSTPFTGGLGQNALGTTGQSTPFAFNVGSTTESKPVFGGTATPTFGQNTPAP 928
              +  S  TSTP  G     ++  +  + P   +  ST  + PV   T   T  + T +P
Sbjct: 2204 TSEGTSMPTSTPSEGSTPFTSMPVS--TMPVVTSEASTLSATPVDTSTPVTTSTEATSSP 2261

Query: 929  ----GVGTSGSSLSFGAS 942
                G     S+LS G +
Sbjct: 2262 TTAEGTSIPTSTLSEGTT 2279



 Score =  116 bits (290), Expect = 1e-25
 Identities = 209/945 (22%), Positives = 349/945 (36%), Gaps = 121/945 (12%)

Query: 94   SGVPASFVPKPGSLKRGLNSQSSDDHLNKRSRSSSMSSLTGAYTSGIPSSSRNAITSSYS 153
            + +P S +P   S    L++   D      + + + SS T A  + IP+S+ +  T+  +
Sbjct: 2223 TSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLT 2282

Query: 154  S---------TRGISQLWKRNGPSSSPFSSPASSRSQTPERPAKKIREEELCHHSSSSTP 204
            S            +S L      S++PF++   + S  P      +        S  +TP
Sbjct: 2283 SIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTST---SSEGNTP 2339

Query: 205  LAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGY 264
            L     S    A+  T          STP ++           S+ G   T      +  
Sbjct: 2340 LTRMPVSTTMVASFETSTLSTTPADTSTPVTTY----------SQAGSSPTTADDTSMPT 2389

Query: 265  SITAEDLDLEKKASLQWFNQALEDKSDAASNSV-TETPPTTQPSFTFTLPAAATASPPTS 323
            S  +E         +        + S  ++  V T TP TT    + +   A   S PTS
Sbjct: 2390 STYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTS 2449

Query: 324  LLAPSTNPLLESLKKMQTPP--------SLPPCPESAGAAT-TEALSPPKTPS-LLPPLG 373
              +  T PL  S+    TP         S  P   S    T TEA S P T   ++ P+ 
Sbjct: 2450 PPSEGTTPLA-SMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPIS 2508

Query: 374  LSQSGPPGLLPSPSFDS---KPPTTLLGLIPAPS---MVPATDTKAPPTLQAETATKPQA 427
             +  G   L   P   +    P  + L   P  S   +V +T+  +  T  AE  + P +
Sbjct: 2509 TASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSAT-SAEGTSMPTS 2567

Query: 428  TSAPSPAPKQSFLFGTQ----------NTSPSSPAAPAASSASPMFKPIFTAPPKSEKEG 477
            T +    P +S    T+          +T+P   + P  +S      P            
Sbjct: 2568 TYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPIST 2627

Query: 478  PTPPGPSVTA----TAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVP-------LPAPFF 526
            P+    S+T+    T P +SS  +T STT    + + ++    +S P       +P    
Sbjct: 2628 PSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTP 2687

Query: 527  KQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTT 586
             + +TP T    +  L     ++T +  P+ +++P T SA            +SSS +T 
Sbjct: 2688 GERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAE-----------ASSSPTTA 2736

Query: 587  TSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTAT 646
              T+   S P     P          + SI     P A    +TV+T +      V T+T
Sbjct: 2737 EGTSMRISTPSDGSTP----------LTSILVSTLPVASSEASTVSTTAVDTSIPVTTST 2786

Query: 647  SSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPA 706
             +S++  +   +++ TS P+ +S P  +     TP  +   G+ + +P+ +         
Sbjct: 2787 EASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTK 2846

Query: 707  FGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVPAHVPTPIQPT 766
              ++     G   P  T S GS+     ++ P   T    + AST+   P     P+  +
Sbjct: 2847 ASSSPTTAEGIVVPISTASEGSTLL---TSIPVSTTPVASSEASTLSTTPVDTSIPVTTS 2903

Query: 767  FGGATH--SAFGLK---ATASAFGAP-----------ASSQPAFGGSTAVFSFGAATSSG 810
              G++   +A G     +T S    P           A S+ +   +T V +    T+S 
Sbjct: 2904 TEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSA 2963

Query: 811  FGATTQTASSGSSSSVFGSTTP----SPFT-FGGSAAPAGSGSFGINVATPGSSATTGAF 865
              +++ T + G+S  +   +TP    +P T    S  P  S        TP  ++T    
Sbjct: 2964 EASSSPTTAEGTSMPI---STPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTT 3020

Query: 866  SFGAGQSGSTAT------STPFTGGLGQNALGTTGQSTPFAFNVGSTTESKPVFGGT--A 917
            S  A  S +TA       STP  G     ++  +  +TP A    ST  + PV   +   
Sbjct: 3021 STEASSSPTTAEGTGIPISTPSEGSTPLTSIPVS--TTPVAIPEASTLSTTPVDSNSPVV 3078

Query: 918  TPTFGQNTPAPGVGTSGSSLSFGASSAPAQGF-VGVGPFGSAAPS 961
            T T   ++P P  GTS    ++   S P  G  V   P  S+A S
Sbjct: 3079 TSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAIS 3123



 Score =  114 bits (286), Expect = 3e-25
 Identities = 219/933 (23%), Positives = 340/933 (36%), Gaps = 141/933 (15%)

Query: 90   PLVASGVPASFVPKPGSLKRGLNSQSSDDHLNKRSRSSSMSSLTGAYTSGIPSS------ 143
            PL +  V  S +P   S    L++   D      + S + SS T    + IP+S      
Sbjct: 512  PLTSMSV--STMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGS 569

Query: 144  --------SRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRSQTPERPAKKIREEEL 195
                    S   + SS +ST   +        ++S  +S +S+ ++    P     E   
Sbjct: 570  TPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGT 629

Query: 196  CHHSSS-STPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQL 254
               S S ST L A  E+       TTP       + ST  +S     +   +P+    + 
Sbjct: 630  TITSMSVSTTLVASSEAS---TLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEG 686

Query: 255  TLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVT----ETPPTTQPSFTF 310
            + P        +T+  +           N  L   S+A++ S T     TP TT    + 
Sbjct: 687  STP--------LTSMPV-----------NTTLVASSEASTLSTTPVDTSTPVTTSTEASS 727

Query: 311  TLPAAATASPPTSLLAPSTNPL--------LESLKKMQTPPSLPPCPESAGAATTEA-LS 361
            +   A  AS PTS  +  + PL        L +  +  T  + P    +    +TEA  S
Sbjct: 728  SPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCS 787

Query: 362  PPKTPSLLPPLGLSQSGPPGLLPSP---SFDSKPPTTLLGLIPAPSMVP---ATDTKAPP 415
            P  T     P+     G P L   P   +  + P  + L   P  S  P   +T+  + P
Sbjct: 788  PTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSP 847

Query: 416  TLQAETATKPQATSAPSPAPKQSF----------LFGTQNTSPSSPAAPAASS----ASP 461
            T  AE  + P +T +    P  S              T +T+P   + P  +S    +SP
Sbjct: 848  T-PAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSP 906

Query: 462  MFKPIFTAPPKSEKEGPTP-------PGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMG 514
                  + P  +  EG TP         P V++ A + S+ P  TST   T     SS  
Sbjct: 907  TTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPT 966

Query: 515  PPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASP---STDSASKPAF 571
                  +P     + TTP T+   +  L     ++T +  P+ S +P   ST+++S P  
Sbjct: 967  TAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPT 1026

Query: 572  GFGINSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTV 631
              G +  +S+    +T          +  + + S  S TPA              T+T V
Sbjct: 1027 AEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPA-------------DTSTPV 1073

Query: 632  TTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATS----SQPTLTFSNTSTPTFNIPF 687
            TT+SQ+  ++     +S        GST  TS P ++    S    T S T   T +IP 
Sbjct: 1074 TTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDT-SIPV 1132

Query: 688  GSSAK-SPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPA----- 741
             +S + S  P+       P    +EG  P A+ P  T    SS     S  P  +     
Sbjct: 1133 TTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVA 1192

Query: 742  ---TAPTPAPASTIKIVPAHVP----TPIQPTFGGATHSAFGLKATASAFGAPASSQPAF 794
                A +P P + +  +P   P    TP+       T  A    +T S      S+    
Sbjct: 1193 TSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTT 1252

Query: 795  GGSTAVFSFGAATSSGFGATTQTASSGSS--SSVFGSTT--PSP------FTFGGSAAPA 844
               T   S    T+ G    T T S GS+  +S+  STT   SP       T   +  P 
Sbjct: 1253 SAET---SSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPV 1309

Query: 845  GSGSFGINVATP--GSSATTGAFSFGAGQSGSTATSTPFTGGLGQNALGTT--GQSTPFA 900
             + +   +  TP  G+S  T  +S G     S   +T        + L TT    STP  
Sbjct: 1310 VTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTP-- 1367

Query: 901  FNVGSTTESKPVFGGTATPTFGQNTPAPGVGTS 933
              V ++TE+       ++PT  + T  P    S
Sbjct: 1368 --VTTSTEA------CSSPTTSEGTSMPNSNPS 1392



 Score =  114 bits (286), Expect = 3e-25
 Identities = 224/979 (22%), Positives = 350/979 (35%), Gaps = 173/979 (17%)

Query: 83   SGHSAFEPLVASGVPASFVPKPGSLKRGLNSQSSDDHLNKRSRSSSMSSLTGAYTSGIPS 142
            S  S   PL+ S +P S  P        L++   D +       S + + T   +S IP+
Sbjct: 2095 SAPSEGSPLLTS-IPLSTTPVASPEASTLSTTPVDSN-------SPVITSTEVSSSPIPT 2146

Query: 143  SSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRSQTPERPAKKIREEELCHHSSSS 202
               +  TS+YS  R  + L      ++   SS  S+ S TP                 +S
Sbjct: 2147 EGTSMQTSTYSDRR--TPLTSMPVSTTVVASSAISTLSTTPV---------------DTS 2189

Query: 203  TPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQL 262
            TP+    E+   +++ TT        S  + GS+      V  +P    E  TL   P  
Sbjct: 2190 TPVTNSTEA---RSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATP-- 2244

Query: 263  GYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETPPTTQPSFTFTLPAAATASPPT 322
                    +D                         T TP TT    T +   A   S PT
Sbjct: 2245 --------VD-------------------------TSTPVTTSTEATSSPTTAEGTSIPT 2271

Query: 323  SLLAPSTNPL--------LESLKKMQTPPSLPPCPESAGAATTEALSPPKTPS-LLPPLG 373
            S L+  T PL        L +  ++ T  + P    +    +TEA SPP T      P  
Sbjct: 2272 STLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTS 2331

Query: 374  LSQSGPPGLLPSP---SFDSKPPTTLLGLIPAPSMVPAT-------------DTKAPPTL 417
             S  G   L   P   +  +   T+ L   PA +  P T             DT  P + 
Sbjct: 2332 TSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTST 2391

Query: 418  QAETATKPQATSAP-SPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKP-------IFTA 469
             +E +T    TS P S  P  S    T +T+P   + P  +S      P       I T+
Sbjct: 2392 YSEGSTP--LTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTS 2449

Query: 470  PPKSEKEGPTPPG-------PSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLP 522
            PP    EG TP         P V++ A + S+ P  TST   T     SS      + +P
Sbjct: 2450 PPS---EGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVP 2506

Query: 523  APFFKQTTTPATA-PTTTAPLFTGLASATSAVAPITSASPSTDS---------------- 565
                 + +T  T+ P +T P+ +  AS T +  P+ S SP   S                
Sbjct: 2507 ISTASEGSTLLTSIPVSTTPVASPEAS-TLSTTPVDSNSPVVTSTEISSSATSAEGTSMP 2565

Query: 566  ----------------ASKPAFGFGINSVSSSSVST----TTSTATAASQPFL--FGAPQ 603
                            ++KP      +++S++ V T    TTST T++S         P 
Sbjct: 2566 TSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPI 2625

Query: 604  ASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATS 663
            ++ +  + ++ SI     P A    +T++T      T V T+T +S++  +  GS++ TS
Sbjct: 2626 STPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTS 2685

Query: 664  APATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKPALT 723
             P   S P      ++T   N    + + +P+ +           ++     G +    T
Sbjct: 2686 TPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRIST 2745

Query: 724  PSFGSSFTFGNSAAPAPATAPTPAPASTIKI---VPAHVPTPI--QPTFGGATHSAFGLK 778
            PS GS+       +  P  +   +  ST  +   +P    T     PT    T       
Sbjct: 2746 PSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMP---T 2802

Query: 779  ATASAFGAPASSQPAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSVFGSTTPSPFTFG 838
            +T S    P +S P      A    G  +++    +T   +S  +SS       SP T  
Sbjct: 2803 STPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASS-------SPTTAE 2855

Query: 839  GSAAPAGSGSFGINVATPGSSATTGAFSFGAGQSGSTATSTPFTGGLGQNALGTTGQSTP 898
            G   P  + S G  + T    +TT      A    ST ++TP    +      T G S+P
Sbjct: 2856 GIVVPISTASEGSTLLTSIPVSTTPV----ASSEASTLSTTPVDTSIPVTT-STEGSSSP 2910

Query: 899  FAFNVGSTTESKPVFGGTATPTFGQNTPAPGVGTSGSSLSFGASSAPAQGFVGVGPFGSA 958
                  S   S P    T   +   +T  P  G+  S+LS   +    +  V      S+
Sbjct: 2911 TTAEGTSMPISTPSEVSTPLTSILVST-VPVAGSEASTLS--TTPVDTRTPVTTSAEASS 2967

Query: 959  APSFSIGAGS--KTPGARQ 975
            +P+ + G      TPG R+
Sbjct: 2968 SPTTAEGTSMPISTPGERR 2986



 Score =  108 bits (269), Expect = 3e-23
 Identities = 172/714 (24%), Positives = 271/714 (37%), Gaps = 128/714 (17%)

Query: 309 TFTLPAAATASPPTSLLAPSTNPLLESLKKM------------QTPPSLPPCPESAGAAT 356
           T T   +     P   L+ STNP + S++               TP       ES   +T
Sbjct: 67  TATGTTSTNVVEPRMYLSCSTNPEMTSIESSVTSDTPGVSSTRMTPTESRTTSESTSDST 126

Query: 357 T------EALSPPKTPS-----LLPPLGLSQSGPPGLL---PSPSFDSKPPTTLLGLIPA 402
           T      E  S P TP      +  P   S S     +   P PSF++    T    +  
Sbjct: 127 TLFPSSTEDTSSPTTPEGTDVPMSTPSEESISSTMAFVSTAPLPSFEAYTSLTYKVDMST 186

Query: 403 PSMVPATDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPM 462
           P +  +T   + PT   E+ T P++T++    P  S    T   + SS A    ++   +
Sbjct: 187 P-LTTSTQASSSPTTP-ESTTIPKSTNSEGSTPLTSMPASTMKVA-SSEAITLLTTPVEI 243

Query: 463 FKPIFTAPPKSEKEGPTPPGPSVTATAPSSSSLPTT-----------------TSTTAPT 505
             P+ T   ++     T  GPS++ +APS  S P T                 ++T A T
Sbjct: 244 STPV-TISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAAT 302

Query: 506 FQPVFSSMGPPAS------VPLPAPFFKQTTTPATA-PTTTAPLFTGLASATSAVAPI-- 556
             PV +S    +S        +P   + + +TP T+ P +T P+ T   S T ++ P+  
Sbjct: 303 NIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMS-TLSITPVDT 361

Query: 557 -TSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGS 615
            T  + ST+ +S P      + ++S+    +T          L  + +AS  S  P    
Sbjct: 362 STLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSK 421

Query: 616 IF--QFGKPPALPTTTTVTTFSQSLP-------TAVPTAT----SSSAADFSGFG----- 657
            F     +  + PTT   T+ + S P       T++P +T    SS A++ S        
Sbjct: 422 TFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKT 481

Query: 658 ----STLATSAPATS---SQPTLTFSNTSTPTFNI-----PFGSSAKSPLPSYPGANPQP 705
               ST A+S+P T+   S PT T S  STP  ++     P  SS  S L + P     P
Sbjct: 482 QVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTP 541

Query: 706 AFGAAEGQ-----PPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVPAHVP 760
              ++E       P G + P  TPS GS             T  T  P ST  +V +   
Sbjct: 542 VTTSSEASSSSTTPEGTSIPTSTPSEGS-------------TPLTNMPVSTRLVVSSEAS 588

Query: 761 TPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAATSSGFGATTQTASS 820
           T         T      +A++S+  A  +S P     T+ +S    T +    +T   +S
Sbjct: 589 TTSTTPADSNTFVTTSSEASSSSTTAEGTSMP-----TSTYSERGTTITSMSVSTTLVAS 643

Query: 821 GSSSSVFGSTTP----SPFTFGGSAAPAGSGSFGINVATPGSSATTGAFSFGAGQSGSTA 876
             +S++  STTP    +P T    A  +       +    G+S  T  ++ G+    S  
Sbjct: 644 SEASTL--STTPVDSNTPVTTSTEATSS-------STTAEGTSMPTSTYTEGSTPLTSMP 694

Query: 877 TSTPFTGGLGQNALGTTGQSTPFAFNVGSTTESKPVFG-GTATPTFGQNTPAPG 929
            +T        + L TT   T       +   S P    G + PT   +TP+ G
Sbjct: 695 VNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPT---STPSEG 745



 Score =  108 bits (269), Expect = 3e-23
 Identities = 210/950 (22%), Positives = 347/950 (36%), Gaps = 108/950 (11%)

Query: 86   SAFEPLVASGVPA-SFVPKPGSLKRGLNSQSSDDHLNKRSRSSSMSS-LTGAYTSGIPSS 143
            ++FE    S  PA +  P     + G +  ++DD     S  S  S+ LT    S +P  
Sbjct: 2351 ASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVV 2410

Query: 144  SRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRSQTPERPAKKIREEELCHHSSSST 203
            S  A T S +     + +      SSSP ++  +S   +P           L     S+T
Sbjct: 2411 SSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTT----PLASMPVSTT 2466

Query: 204  PLAADKESQ-GEKAADTTPRKKQNSNSQSTP---------------GSSGQRKRKVQLLP 247
            P+ + +         DT+     ++ + S+P               GS+      V   P
Sbjct: 2467 PVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTP 2526

Query: 248  SRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETPPTTQP- 306
                E  TL   P    S      ++   A+               S  +   P +T+P 
Sbjct: 2527 VASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPL 2586

Query: 307  ----SFTFTLPAAATASPPTSLLAPSTNPLLESLKKMQTPPSLPP-------------CP 349
                + T +     T+ P T+    S++P   + K    P S P               P
Sbjct: 2587 ASSEASTLSTTPVDTSIPVTTSTETSSSPT--TAKDTSMPISTPSEVSTSLTSILVSTMP 2644

Query: 350  ESAGAATTEALSPPKTPSLLPPLGLSQSGP------------PGLLPSPSFDSKPPTTLL 397
             ++  A+T + +P  T +L+     + S P            PG   +P  +    TTLL
Sbjct: 2645 VASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLL 2704

Query: 398  GLIPAPSM-VPATDTKAPPTLQAETATKPQ---------ATSAPSPAPKQSFLFGTQNTS 447
                A ++     DT  P T  AE ++ P          +T +    P  S L  T   +
Sbjct: 2705 ANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVA 2764

Query: 448  PSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQ 507
             SS A+  +++A     P+ T+   S     T    S+  + PS +S P T+     T  
Sbjct: 2765 -SSEASTVSTTAVDTSIPVTTSTEASSSP-TTAEVTSMPTSTPSETSTPLTSMPVNHT-- 2820

Query: 508  PVFSS-MGPPASVPLPAPFFKQTTTPATA-PTTTAPLFTGLASATSAVAPITSASPSTDS 565
            PV SS  G  ++ P+       T+T A++ PTT   +   +++A+     +TS   ST  
Sbjct: 2821 PVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTP 2880

Query: 566  ASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGA--PQASAASFTPAMGSIFQFGKPP 623
             +         +   +S+  TTST  ++S     G   P ++ +  +  + SI     P 
Sbjct: 2881 VASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPV 2940

Query: 624  ALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTF 683
            A    +T++T      T V T+  +S++  +  G+++  S P     P LT  + ST   
Sbjct: 2941 AGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTP-LTSMSVST--- 2996

Query: 684  NIPFGSSAKSPLPSYPGANPQPAFGAAEGQPP-----GAAKPALTPSFGSSFTFGNSAAP 738
             +P  SS  S L   P     P   + E         G   P  TPS GS+       + 
Sbjct: 2997 -MPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVST 3055

Query: 739  APATAP-------TPAPASTIKIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQ 791
             P   P       TP  +++  +    V +   P  G +   +   + +    G P S+ 
Sbjct: 3056 TPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTT 3115

Query: 792  PAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSA----APAG-- 845
            P    + +  S     +S    TT T +  S ++  G++ P+     GS      P    
Sbjct: 3116 PVTSSAISTLSTTPVDTS-TPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTM 3174

Query: 846  ---SGSFGINVATPGSSAT-----TGAFSFGAGQSGSTATSTPFTGGLGQNALGTTGQST 897
               S       ATP  ++T     T A S    +  S  TSTP  G     ++  +  +T
Sbjct: 3175 LVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVS--NT 3232

Query: 898  PFAFNVGSTTESKPVFGGT--ATPTFGQNTPAPGVGTSGSSLSFGASSAP 945
            P A +  S   + PV   T   T T   ++P    GTS  + +    S P
Sbjct: 3233 PVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTP 3282



 Score =  107 bits (267), Expect = 6e-23
 Identities = 210/918 (22%), Positives = 360/918 (39%), Gaps = 121/918 (13%)

Query: 94   SGVPASFVPKPGSLKRGLNSQSSDDHLNKRSRSSSMSSLTGAYTSGIPSSSRNAITSSYS 153
            + +P S  P   S    L++   D  +   + +   SS T A  + +P S+ + +++  +
Sbjct: 2872 TSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLT 2931

Query: 154  STRGISQLWKRNGPSSSPFSSP------------ASSRSQTPERPAKKI-----REEELC 196
            S   +S +      +S+  ++P            ASS   T E  +  I     R   L 
Sbjct: 2932 SIL-VSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLT 2990

Query: 197  HHSSSSTPLAADKESQGEKA-ADTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLT 255
              S S+ P+A+ + S   +  ADT+     ++ + S+P ++      +   PS     LT
Sbjct: 2991 SMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPIST-PSEGSTPLT 3049

Query: 256  LPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETPPTTQPSFTFTLPAA 315
              P       ++   + + + ++L      ++  S   +++   + PT     +  +   
Sbjct: 3050 SIP-------VSTTPVAIPEASTLS--TTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTY 3100

Query: 316  ATASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALSPPKTPSLLPPLGLS 375
            +  S P + +  ST P+  S   + T  + P    +    +TEA S P T       G S
Sbjct: 3101 SEGSTPLTGVPVSTTPVTSSA--ISTLSTTPVDTSTPVTTSTEAHSSPTTSE-----GTS 3153

Query: 376  QSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPAT--DTKAPPTLQAE--TATKPQATSAP 431
                     S      P +T+L +    S + AT  DT  P T   E  ++T  + TS P
Sbjct: 3154 MPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIP 3213

Query: 432  SPAPKQSFLFGTQNTSPSSPAAPAASSASPMFK--------PIFTA------PPKSE--- 474
            +  P +     T  TS      P ASS + +          P+ T+      PP +E   
Sbjct: 3214 TSTPSEGM---TPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTS 3270

Query: 475  ------KEGPTP----PGPSVTATAPSSSSLPTT---TSTTAPTFQPVFSSMGPPASVPL 521
                   EG TP    P  + T  +  +S+L TT   TST   T+    SS        +
Sbjct: 3271 MPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSM 3330

Query: 522  PAPFFKQTTTPATAPT-TTAPLFTGLASATSAVAPITSASP---STDSASKPAFGFGINS 577
            P   + + +TP T  + +T P+ +  AS T +  P+ +++P   ST+++  P    G + 
Sbjct: 3331 PTSTYSEGSTPLTNMSFSTTPVVSSEAS-TLSTTPVDTSTPVTTSTEASLSPTTAEGTSI 3389

Query: 578  VSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQS 637
             +SS    TT  A+         + + +  S TP   +         L TT+T  + S +
Sbjct: 3390 PTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSN--------TLVTTSTEASSSPT 3441

Query: 638  LP--TAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFS--NTSTPTFNIPFGSSAKS 693
            +   T++PT+T+S  +        L+T+  A+S   TL+ +  +TSTP       SS  +
Sbjct: 3442 IAEGTSLPTSTTSEGSTPLSI-MPLSTTPVASSEASTLSTTPVDTSTPVTT----SSPTN 3496

Query: 694  PLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPA----TAPTPAPA 749
              P+       P   A EG  P    P  T    SS     S  P  +    T+ + A +
Sbjct: 3497 SSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASS 3556

Query: 750  S--TIKIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAAT 807
            S  T+++    + TP + +    T        T+S    P  S P+   ST V +   + 
Sbjct: 3557 SPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTP--STPSVDRSTPVTTSTQSN 3614

Query: 808  SSGFGATTQTASSGSSSSVFGSTTPSPF-TFGGSAAPAGSGS-FGINVATPGSSATTGAF 865
            S+       T    + S V    T  P  T   + + AG+ S   ++ +TP  ++T  + 
Sbjct: 3615 STPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSS 3674

Query: 866  SFGAGQSGSTATSTPFTGGLGQNALGTTGQSTPFAFNVGSTTESKPVFGGT-ATPTFGQN 924
            S    +  +    TP  G            STP      STT      G T +TP+   +
Sbjct: 3675 SPVTPEGTTMPIWTPSEG------------STPLTTMPVSTTRVTSSEGSTLSTPSVVTS 3722

Query: 925  TPAPGVGTSGSSLSFGAS 942
            TP   V TS  ++S  A+
Sbjct: 3723 TP---VTTSTEAISSSAT 3737



 Score =  102 bits (254), Expect = 2e-21
 Identities = 211/945 (22%), Positives = 345/945 (36%), Gaps = 143/945 (15%)

Query: 20   SAIPEQIISSTLSSPSSNAPDPCAKETVLSALKEKKKKRTVEEEDQIFLDGQENKRRRHD 79
            ++ P + ++   S P SN P   ++ ++LS         T  + +       E       
Sbjct: 3214 TSTPSEGMTPLTSVPVSNTPVASSEASILST--------TPVDSNTPLTTSTEASSSPPT 3265

Query: 80   SSGSGHSAFEPLVASGVPASFVPKPGSLKRGLNSQSSDDHLNKRSRSSSMSSLTGAYTSG 139
            + G+      P   S    S    P S     +S++S         S+ +++ + A +S 
Sbjct: 3266 AEGTSMPTSTPSEGSTPLTSM---PVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSP 3322

Query: 140  IPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRSQTP---ERPAKKIREEELC 196
              +   +  TS+YS   G + L   +  ++   SS AS+ S TP     P     E  L 
Sbjct: 3323 PIADGTSMPTSTYSE--GSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLS 3380

Query: 197  HHSSSSTPLAADKESQG-----EKAADTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRG 251
              ++  T +     S+G          TTP      N+ ST          +    +   
Sbjct: 3381 PTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNT---LVTTSTEAS 3437

Query: 252  EQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETPPTTQPSFTFT 311
               T+     L  S T+E         L     A  + S  ++  V  + P T  S T +
Sbjct: 3438 SSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNS 3497

Query: 312  LPAAA-TASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALSPPKTPSLLP 370
             P  A   S PTS     + PL        T   +   P ++  A+T + +P  + + + 
Sbjct: 3498 SPTTAEVTSMPTSTAGEGSTPL--------TNMPVSTTPVASSEASTLSTTPVDSNTFVT 3549

Query: 371  PLGLSQSGPPGL------LPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAETATK 424
                + S P  L      + +PS  S   TT+L                   L +   T 
Sbjct: 3550 SSSQASSSPATLQVTTMRMSTPSEGSSSLTTML-------------------LSSTYVTS 3590

Query: 425  PQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPPGPS 484
             +A++  +P+  +S    T   S S+P  P   +  PM  P   + P +     T    S
Sbjct: 3591 SEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITL-PMSTPSEVSTPLTIMPVSTT---S 3646

Query: 485  VTAT-APSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTAPLF 543
            VT + A ++S+LP  TST   T   V SS   P    +P     + +TP T    +    
Sbjct: 3647 VTISEAGTASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRV 3706

Query: 544  TGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQ 603
            T    +T +   + +++P T S             + SS +T  ST  + S P      +
Sbjct: 3707 TSSEGSTLSTPSVVTSTPVTTSTE-----------AISSSATLDSTTMSVSMPM-----E 3750

Query: 604  ASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATS 663
             S    T              L +TT VT F +S   ++P+  +S +   +  GS+  T+
Sbjct: 3751 ISTLGTT-------------ILVSTTPVTRFPESSTPSIPSVYTSMSMTTASEGSSSPTT 3797

Query: 664  APATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPG-AAKPAL 722
               T++ P  T S  ST    +             P +   P+  +    PPG  + P L
Sbjct: 3798 LEGTTTMPMSTTSERSTLLTTVLIS----------PISVMSPSEASTLSTPPGDTSTPLL 3847

Query: 723  TPSFGSSFTFGNSAAPAPATAPTPAPASTIKI-VPAHVPTPIQPTFGGATHSAFGLKATA 781
            T +   SF+              PA  +TI+I + +   TP+       T          
Sbjct: 3848 TSTKAGSFSI-------------PAEVTTIRISITSERSTPLTTLLVSTT-------LPT 3887

Query: 782  SAFGAPASSQPAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSA 841
            S  GA  +S P    ST   +F  +T +    T   A++ S S +   +TP    F  S 
Sbjct: 3888 SFPGASIASTPPLDTST---TFTPSTDTASTPTIPVATTISVSVITEGSTPGTTIFIPS- 3943

Query: 842  APAGSGSFGINVATPGSSATTGAFSFGAGQSGSTATSTPFTGGLGQNALGTTGQSTPFAF 901
             P  S +  +  AT G+ +T            ST  +TP T     ++  TT  ST   F
Sbjct: 3944 TPVTSSTADVFPATTGAVSTP--------VITSTELNTPST----SSSSTTTSFSTTKEF 3991

Query: 902  NVGSTTESKPV-FGGTATPTFGQNTPAPGVGTSGSSLSFGASSAP 945
               + T + P+ +   +T      T + G  TS S+LS  A+S P
Sbjct: 3992 TTPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSASTLS--ATSTP 4034



 Score = 90.9 bits (224), Expect = 5e-18
 Identities = 172/717 (23%), Positives = 270/717 (37%), Gaps = 102/717 (14%)

Query: 96   VPASFVPKPGSLKRGLNSQSSDDHLNKRSRSSSMSSLTGAYTSGIPSS------------ 143
            +P S  P   S    L++   D      + S + SS T A  + +P+S            
Sbjct: 3463 MPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNM 3522

Query: 144  --SRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRSQTPERPAKKIREEELCHHSSS 201
              S   + SS +ST   + +      +SS   S ASS   T +    ++        S +
Sbjct: 3523 PVSTTPVASSEASTLSTTPVDSNTFVTSS---SQASSSPATLQVTTMRMSTPSEGSSSLT 3579

Query: 202  STPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTLP--PP 259
            +  L++   +  E +  +TP     S  +STP ++  +       P    E +TLP   P
Sbjct: 3580 TMLLSSTYVTSSEASTPSTP-----SVDRSTPVTTSTQSNSTPTPP----EVITLPMSTP 3630

Query: 260  PQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETP----PTTQPSFTFTLPAA 315
             ++   +T   +      ++     A     D ++  +T T     P T    T  +   
Sbjct: 3631 SEVSTPLTIMPVSTTS-VTISEAGTASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTP 3689

Query: 316  ATASPPTSLLAPSTNPLLESLKKMQTPPSL---PPCPESAGAATTEALSPPKTPSLLPPL 372
            +  S P + +  ST  +  S     + PS+    P   S  A ++ A     T S+  P+
Sbjct: 3690 SEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAISSSATLDSTTMSVSMPM 3749

Query: 373  GLSQSGPPGLL---PSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAETATKPQATS 429
             +S  G   L+   P   F      ++  +  + SM  A++  + PT    T T P +T+
Sbjct: 3750 EISTLGTTILVSTTPVTRFPESSTPSIPSVYTSMSMTTASEGSSSPTTLEGTTTMPMSTT 3809

Query: 430  APSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPP--KSEKEGPTPPGPSVTA 487
            +     ++S L  T   SP S  +P+ +S      P  T+ P   S K G       VT 
Sbjct: 3810 S-----ERSTLLTTVLISPISVMSPSEASTLST-PPGDTSTPLLTSTKAGSFSIPAEVTT 3863

Query: 488  ---TAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTT-TPAT--APTTTAP 541
               +  S  S P TT   + T    F    P AS+    P    TT TP+T  A T T P
Sbjct: 3864 IRISITSERSTPLTTLLVSTTLPTSF----PGASIASTPPLDTSTTFTPSTDTASTPTIP 3919

Query: 542  LFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFL--- 598
            + T     T +V+ IT  S    +   P+       V+SS+     +T  A S P +   
Sbjct: 3920 VAT-----TISVSVITEGSTPGTTIFIPS-----TPVTSSTADVFPATTGAVSTPVITST 3969

Query: 599  -FGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATS----SSAADF 653
                P  S++S T +  +  +F   PA+ T   +T  + S   + P  TS    +SA+  
Sbjct: 3970 ELNTPSTSSSSTTTSFSTTKEF-TTPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSASTL 4028

Query: 654  SGFG----STLATSAPAT----SSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQP 705
            S       ST  T+ P T    SS+P+   S+T  PTF     S+  +   S    NP+ 
Sbjct: 4029 SATSTPHTSTSVTTRPVTPSSESSRPSTITSHTIPPTFPPAHSSTPPTTSASSTTVNPEA 4088

Query: 706  AFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPA-STIKIVPAHVPT 761
                     P       T SF             P    T  P  +TIK  P   PT
Sbjct: 4089 VTTMTTRTKPSTR----TTSF-------------PTVTTTAVPTNTTIKSNPTSTPT 4128



 Score = 77.8 bits (190), Expect = 5e-14
 Identities = 101/405 (24%), Positives = 159/405 (39%), Gaps = 55/405 (13%)

Query: 293  ASNSVTETPPTTQPSF--TFTLPAAATASP----PTSLLAPSTNPLLESLKK--MQTPPS 344
            ++  VT  P ++ PS    +T  +  TAS     PT+L   +T P+  + ++  + T   
Sbjct: 3761 STTPVTRFPESSTPSIPSVYTSMSMTTASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVL 3820

Query: 345  LPPCPESAGAATTEALSPP---KTPSLLPPLGLSQSGPPGL----LPSPSFDSKPPTTLL 397
            + P    + +  +   +PP    TP L      S S P  +    +   S  S P TTLL
Sbjct: 3821 ISPISVMSPSEASTLSTPPGDTSTPLLTSTKAGSFSIPAEVTTIRISITSERSTPLTTLL 3880

Query: 398  GLIPAPSMVPATDTKAPPTLQAETATKPQATSAPSP----APKQSFLFGTQNTSPSS--- 450
                 P+  P     + P L   T   P   +A +P    A   S    T+ ++P +   
Sbjct: 3881 VSTTLPTSFPGASIASTPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEGSTPGTTIF 3940

Query: 451  -PAAPAASSASPMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPV 509
             P+ P  SS + +F       P +     TP   S     PS+SS  TTTS     F   
Sbjct: 3941 IPSTPVTSSTADVF-------PATTGAVSTPVITSTELNTPSTSSSSTTTS-----FSTT 3988

Query: 510  FSSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKP 569
                 P  +   P  +   +T P+T  TT+    T  ++ ++   P TS S +T      
Sbjct: 3989 KEFTTPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSASTLSATSTPHTSTSVTT------ 4042

Query: 570  AFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTT 629
                    V+ SS S+  ST T+ + P  F      A S TP   S       P   TT 
Sbjct: 4043 ------RPVTPSSESSRPSTITSHTIPPTF----PPAHSSTPPTTSASSTTVNPEAVTTM 4092

Query: 630  TVTTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLT 674
            T  T   +  T+ PT T+++        +T+ ++  +T + P  T
Sbjct: 4093 TTRTKPSTRTTSFPTVTTTAVPT----NTTIKSNPTSTPTVPRTT 4133



 Score = 64.3 bits (155), Expect = 5e-10
 Identities = 136/615 (22%), Positives = 216/615 (35%), Gaps = 94/615 (15%)

Query: 104  PGSLKRGLNSQSSDDHLNKRSRSSSMSSLTGAYTSGIPSSSRNAITSSYSSTRGISQLWK 163
            P S  R  +S+ S         S+ +++ T A +S   S++ ++ T S S    IS L  
Sbjct: 3700 PVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAISS---SATLDSTTMSVSMPMEISTLGT 3756

Query: 164  RNGPSSSPFSSPASSRSQTPERPAKKIREEELCHHSSSSTPLAADKESQGEKAADTTPRK 223
                S++P +      S TP  P+          ++S S   A++  S       TT   
Sbjct: 3757 TILVSTTPVTR--FPESSTPSIPSV---------YTSMSMTTASEGSSSPTTLEGTTTMP 3805

Query: 224  KQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPP-----QLGYSITAEDLDLEKKAS 278
               ++ +ST  ++        + PS   E  TL  PP      L  S  A    +  + +
Sbjct: 3806 MSTTSERSTLLTTVLISPISVMSPS---EASTLSTPPGDTSTPLLTSTKAGSFSIPAEVT 3862

Query: 279  LQWFNQALEDKSDAASNSVTETPPTTQPSFTFTLPAAATASPP---TSLLAPSTNPLLES 335
                +   E  +   +  V+ T PT+ P       A+  ++PP   ++   PST+     
Sbjct: 3863 TIRISITSERSTPLTTLLVSTTLPTSFPG------ASIASTPPLDTSTTFTPSTDTA--- 3913

Query: 336  LKKMQTPPSLPPCPESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTT 395
                 + P++P     + +  TE  S P T   +P   ++ S         + D  P TT
Sbjct: 3914 -----STPTIPVATTISVSVITEG-STPGTTIFIPSTPVTSS---------TADVFPATT 3958

Query: 396  LLGLIPAPSMVPATDTKAPPTLQAETATKPQAT---SAPSPAPKQSFLFGTQNTSPSSPA 452
              G +  P ++ +T+   P T  + T T    T   + P+        + T +T+PS+P 
Sbjct: 3959 --GAVSTP-VITSTELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPSTPR 4015

Query: 453  APAASSASPMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSS 512
              +    +       T+ P +     T P   VT ++ SS     T+ T  PTF P  SS
Sbjct: 4016 TTSRGCTTSASTLSATSTPHTSTSVTTRP---VTPSSESSRPSTITSHTIPPTFPPAHSS 4072

Query: 513  MGPPASVPLPA--PFFKQTTTPATAP---TTTAPLFTGLASATSAVAPITSASPSTDSAS 567
              P  S       P    T T  T P   TT+ P  T  A  T+        S  T   +
Sbjct: 4073 TPPTTSASSTTVNPEAVTTMTTRTKPSTRTTSFPTVTTTAVPTNTTIKSNPTSTPTVPRT 4132

Query: 568  KPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPT 627
               FG G  + +S   +  T        P L+          +  +G          L  
Sbjct: 4133 TTCFGDGCQNTASRCKNGGTWDGLKCQCPNLYYGELCEEVVSSIDIGPPETISAQMELTV 4192

Query: 628  TTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPF 687
            T T   F++ L                             SSQ    F  T T   NI +
Sbjct: 4193 TVTSVKFTEELKN--------------------------HSSQEFQEFKQTFTEQMNIVY 4226

Query: 688  GSSAKSPLPSYPGAN 702
                 S +P Y G N
Sbjct: 4227 -----SGIPEYVGVN 4236


>gi|151301154 mucin 6, gastric [Homo sapiens]
          Length = 2439

 Score =  119 bits (299), Expect = 1e-26
 Identities = 172/664 (25%), Positives = 247/664 (37%), Gaps = 81/664 (12%)

Query: 301  PPTT-QPSFTFTLPAAATASPPTSL-----------LAPSTNPLLESLKKMQTPPSLPPC 348
            PPTT QP  T  LP   T S PT +           L  ST P   S     +P   P  
Sbjct: 1198 PPTTPQPPTTPQLPT--TGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLL 1255

Query: 349  PESAGAATTEALS--PPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGL-IPAPSM 405
            P +  ++   A S  PP+  + + P   S   P   L S +  +KP  T       A + 
Sbjct: 1256 PATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTA--TKPTVTQATTRATASTA 1313

Query: 406  VPATDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKP 465
             PAT + A  T +        ATS  SP   +S       T+   P   A  +  P   P
Sbjct: 1314 SPATTSTAQSTTRTTMTLPTPATSGTSPTLPKS-------TNQELPGTTATQTTGPRPTP 1366

Query: 466  IFTAPPKSEKEGPTPPGPSVTATAPSSSSLP-TTTSTTAPTFQPVFSSMGPPASVPLPAP 524
              T  P + + G  P  P+ T T  + ++   TT  T   T  P  +    P++ P+ A 
Sbjct: 1367 ASTTGPTTPQPGQ-PTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTAT 1425

Query: 525  FFKQTTTPATA--PTTTAPLFTGLASATSAVAPITSA--SPSTDSASKPAFGFGINSVSS 580
             F  TTT  T   P TT P         + V P +++  +PST +   P       S S+
Sbjct: 1426 SFHATTTYPTPSHPETTLP---------THVPPFSTSLVTPSTHTVITPTHAQMATSASN 1476

Query: 581  SSVSTTT---STATAASQPFLFGAPQASAASFTPAMGSIFQFGK-PPALPTTTTVTTFSQ 636
             S  T T    T   A+       P     S T    S F   K P +L + T+ T   +
Sbjct: 1477 HSAPTGTIPPPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPE 1536

Query: 637  SLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLP 696
              PT+  T T +  +  +   + +A +  ATSS+P   F+  S PT + PF S+      
Sbjct: 1537 VTPTSTTTITPNPTS--TRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTAT 1594

Query: 697  SYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVP 756
            S+      P         P    P   P F +S        P+  T  TP  A       
Sbjct: 1595 SFKTTTTYPT-----PSHPQTTLPTHVPPFSTSL-----VTPSTHTVITPTHAQMATSAS 1644

Query: 757  AH-VPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAATSSGFGATT 815
             H +PT       G       LKAT S   AP  +    G S A+ S          A T
Sbjct: 1645 IHSMPT-------GTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNT-------AKT 1690

Query: 816  QTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATTGAFSFG----AGQ 871
             T+    +SS   +   S  T   +  P  +G+  + V T G+S +  +FS      +  
Sbjct: 1691 STSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLH 1750

Query: 872  SGSTATSTPFTGGLGQNAL----GTTGQSTPFAFNVGSTTESKPVFGGTATPTFGQNTPA 927
            S +++T  P        ++     +TG  TP A    +T+   P    T +P  G  TP 
Sbjct: 1751 SHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTG-TTPI 1809

Query: 928  PGVG 931
               G
Sbjct: 1810 SSTG 1813



 Score =  115 bits (288), Expect = 2e-25
 Identities = 227/954 (23%), Positives = 339/954 (35%), Gaps = 172/954 (18%)

Query: 69   DGQENKRRRHDSSGSGHSAFEPLVASGVPASFVPKPGSLKRGLNSQSSDDHLNKRSRSSS 128
            DG    +   +++ + H  ++P +    P S    PGS   G  + S D++ +       
Sbjct: 1140 DGHGEYQYTQEANCTWH--YQPCLCPSQPQSV---PGSNIEGCYNCSQDEYFDHEE---- 1190

Query: 129  MSSLTGAYTSGIPSSSRNAITSSYSSTRGI--SQLWKRNGPSSS----PFSSPASSRSQT 182
                 G     +P ++    T+    T G   +Q+W   G S++      + P+ S + T
Sbjct: 1191 -----GVCVPCMPPTTPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHT 1245

Query: 183  PERPAKKIREEELCHHSSSSTPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQRKRK 242
            P  P +      L    +SS P A+  E          PR       Q+T G        
Sbjct: 1246 PASPTQT---PLLPATLTSSKPTASSGEP---------PRPTTAVTPQATSG-------- 1285

Query: 243  VQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETPP 302
                         LPP   L  + T       K    Q   +A    +  A+ S  ++  
Sbjct: 1286 -------------LPPTATLRSTAT-------KPTVTQATTRATASTASPATTSTAQS-- 1323

Query: 303  TTQPSFTFTLPAAATASPPTSLLAPSTNPLLESLKKMQTP-------------------P 343
            TT+ + T   PA +  SP    L  STN  L      QT                    P
Sbjct: 1324 TTRTTMTLPTPATSGTSPT---LPKSTNQELPGTTATQTTGPRPTPASTTGPTTPQPGQP 1380

Query: 344  SLPPCPESAGAATTEALSPPKTPSLL--PPLGLSQSGPPGLLPSPSFD--------SKPP 393
            + P   E+    TT   + P+TP     PP   S     G + + SF         S P 
Sbjct: 1381 TRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTPSHPE 1440

Query: 394  TTLLGLIPAPS---MVPATDTKAPPTLQAETATKPQATSAPSPA-PKQSFLFGTQNTSPS 449
            TTL   +P  S   + P+T T   PT  A+ AT     SAP+   P  + L  T +T  +
Sbjct: 1441 TTLPTHVPPFSTSLVTPSTHTVITPT-HAQMATSASNHSAPTGTIPPPTTLKATGSTHTA 1499

Query: 450  SPAAPAASSASPMFKPIFT--APPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQ 507
             P  P  S  S       T   P        +   P VT   P+S++  T   T+  T  
Sbjct: 1500 PPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVT---PTSTTTITPNPTSTRTRT 1556

Query: 508  PVFSSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSAS 567
            PV  +    +S P P PF   +    ++P ++    T  +  T+   P  S   +T    
Sbjct: 1557 PVAHTNSATSSRP-PPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTH 1615

Query: 568  KPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPT 627
             P F   + + S+ +V T T    A S           A+  +   G+I     PP  PT
Sbjct: 1616 VPPFSTSLVTPSTHTVITPTHAQMATS-----------ASIHSMPTGTI-----PP--PT 1657

Query: 628  TTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPF 687
            T   T  + + PT   T + +S A  S   +   +++  + +  T     TST T NI  
Sbjct: 1658 TLKATGSTHTAPTMTLTTSGTSQA-LSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNI-- 1714

Query: 688  GSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPA 747
                 +P P+  G  P     +   Q   +   A T +   S T   S+   P    T  
Sbjct: 1715 -----TPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHT---SSTHHPEVTST-- 1764

Query: 748  PASTIKIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAAT 807
              ST  I P H  T      G  T  A    AT+S    P ++     G+T + S G  T
Sbjct: 1765 --STTSITPNHTST------GTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVT 1816

Query: 808  SSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATP-GSSATTGAFS 866
            ++ F  TT   +     +   +  PS   F  S     + +  I   T   +SA+  +  
Sbjct: 1817 ATSFQTTTTYPTPSHPHTTLPTHVPS---FSTSLVTPSTHTVIIPTHTQMATSASIHSMP 1873

Query: 867  FGA-------GQSGSTATS---TPFTGGLGQ--NALGTTGQSTPFAFNVGST--TESKPV 912
             G          +GST T+   TP T G  Q  ++  T   ST   ++  ST   E  P 
Sbjct: 1874 TGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPT 1933

Query: 913  FGGTATP---TFGQNTPAPGVGTSGSS---LSFGASSAPAQGFVGVGPFGSAAP 960
                 TP   + G  TP     ++ SS     F   S P     G  PF S  P
Sbjct: 1934 STTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPP----TGSSPFSSTGP 1983



 Score =  110 bits (275), Expect = 7e-24
 Identities = 228/1020 (22%), Positives = 364/1020 (35%), Gaps = 163/1020 (15%)

Query: 28   SSTLSSPSSNAPDPCAKETVLSALKEKKKKRTVEEEDQIFLDGQENKRRRHDSSGSGHSA 87
            S+T+   SS  P P +  T  S  +      T+         G+  +           +A
Sbjct: 1227 STTIGLLSSTGPSPSSNHTPASPTQTPLLPATLTSSKPTASSGEPPRPT---------TA 1277

Query: 88   FEPLVASGVPASFVPKPGSLKRGLNSQSSDDHLNKRSRSSSMSSLTGAYTSGIPSSSRNA 147
              P   SG+P +           L S ++   + + +  ++ S+ + A TS   S++R  
Sbjct: 1278 VTPQATSGLPPTAT---------LRSTATKPTVTQATTRATASTASPATTSTAQSTTRTT 1328

Query: 148  ITSSYSSTRGISQLWKRNG----------PSSSPFSSPASSRSQTPERPAKKIREEEL-- 195
            +T    +T G S    ++            ++ P  +PAS+   T  +P +  R      
Sbjct: 1329 MTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGPTTPQPGQPTRPTATET 1388

Query: 196  -------------CHHSSSSTPLAADK-ESQGEKAADT--------TPRKKQN------- 226
                           H++ S P A     S G   A +        TP   +        
Sbjct: 1389 TQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTPSHPETTLPTHVP 1448

Query: 227  --SNSQSTPGSSGQ-RKRKVQLLPSRRGEQL---TLPPPPQL---GYSITAEDLDLEKKA 277
              S S  TP +         Q+  S         T+PPP  L   G + TA  +      
Sbjct: 1449 PFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGSTHTAPPITPTTSG 1508

Query: 278  SLQWFNQALEDKSDAASNSVTETP--PTTQPSFTFTL----------------------- 312
            + Q  +    +K+  + +S T +   P   P+ T T+                       
Sbjct: 1509 TSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSATSSR 1568

Query: 313  --PAAATASPPT-SLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALSPPKTPSLL 369
              P   T SPPT S    ST P+  +  K  T    P  P++    T     PP + SL+
Sbjct: 1569 PPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQT----TLPTHVPPFSTSLV 1624

Query: 370  PPLGLSQSGPPG--LLPSPSFDSKPPTTLLGLIPAPSMVPAT-DTKAPPTLQAETATKPQ 426
             P   +   P    +  S S  S P     G IP P+ + AT  T   PT+   T+   Q
Sbjct: 1625 TPSTHTVITPTHAQMATSASIHSMPT----GTIPPPTTLKATGSTHTAPTMTLTTSGTSQ 1680

Query: 427  ATSAPSPAPKQSFLFG-TQNTSPSSPAAPAASSASPMFKPIFTA-PPKSEKEGPTPPGPS 484
            A S+ + A   + L   T +T  +   + + ++ +P   P  T  PP +     T    S
Sbjct: 1681 ALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITP--NPTSTGTPPMTVTTSGTSQSRS 1738

Query: 485  VTATAPSSSSL---------PTTTSTTAPTFQPVFSSMGPPASVP---------LPAPFF 526
              +TA +S+SL         P  TST+  +  P  +S G    V          LP PF 
Sbjct: 1739 SFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFT 1798

Query: 527  KQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSV--S 584
              +    T P ++    T  +  T+   P  S   +T     P+F   + + S+ +V   
Sbjct: 1799 THSPPTGTTPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIP 1858

Query: 585  TTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPT 644
            T T  AT+AS   +   P  +    T    +      PP  PTT+     SQS P++  T
Sbjct: 1859 THTQMATSAS---IHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGT---SQS-PSSFST 1911

Query: 645  ATSSSAADF--SGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGAN 702
            A +S++  +  S       T    T+  P  T + T TP  +    SS++ P P    + 
Sbjct: 1912 AKTSTSLPYHTSSTHHPEVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSP 1971

Query: 703  PQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVPAH---- 758
            P          P  +  P    SF ++ T+   + P         P ST  + P+     
Sbjct: 1972 P------TGSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVI 2025

Query: 759  VPTPIQPTFGGATHSA--------FGLKATASAFGAPASSQPAFGGSTAVFSFGAAT-SS 809
            + T  Q     + HS           LKAT S   AP  +    G S    SF  AT SS
Sbjct: 2026 ITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPPMTVTTSGTSQTHSSFSTATASS 2085

Query: 810  GFGATTQTASSGSSSSVFGS--TTPSPFTFGGSAAPAGSGSFGINVATPGSSATTGAFSF 867
             F +++      SSS    S  TT  P     +  P  + +   +  +P  SA +   S+
Sbjct: 2086 SFISSSSWLPQNSSSRPPSSPITTQLPH-LSSATTPVSTTNQLSSSFSPSPSAPSTVSSY 2144

Query: 868  GAGQSGSTATSTPFTGGLGQNALGTTGQSTPFAFNVGSTTESKPVFGGTATPTFGQNTPA 927
                  S  TS+P + G   + +     ST  +    S+  + P     +      ++PA
Sbjct: 2145 VPSSHSSPQTSSP-SVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPA 2203



 Score =  110 bits (274), Expect = 8e-24
 Identities = 179/738 (24%), Positives = 273/738 (36%), Gaps = 104/738 (14%)

Query: 80   SSGSGHSA-FEPLVASGVPASFVP-KPGSLKRGLNSQSSDDHLNKRSRSSSMSSLTGAYT 137
            ++GS H+A    L  SG   +            L+S +S  H  + + +S+ +      +
Sbjct: 1661 ATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTS 1720

Query: 138  SGIP-----SSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRSQTPERPAKKIRE 192
            +G P     +S  +   SS+S+ +  + L      +  P  +  S+ S TP   +   R 
Sbjct: 1721 TGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRT 1780

Query: 193  EELCHHSSSSTPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGE 252
              + H +S+++       +       TTP         ST   +    +     P+    
Sbjct: 1781 P-VAHTTSATSSRLPTPFTTHSPPTGTTP-------ISSTGPVTATSFQTTTTYPTPSHP 1832

Query: 253  QLTLPPP-PQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETPPTTQPSFTFT 311
              TLP   P    S+            +    Q     S  +  + T  PPTT       
Sbjct: 1833 HTTLPTHVPSFSTSLVTPSTHT---VIIPTHTQMATSASIHSMPTGTIPPPTT-----IK 1884

Query: 312  LPAAATASPPTSLLAPSTNPLLESLKKMQTPPSLP------PCPESAGAATTEALSPPKT 365
               +   +PP +     T+    S    +T  SLP        PE    +TT       +
Sbjct: 1885 ATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPTSTTNITPKHTS 1944

Query: 366  PSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAETATKP 425
                 P+  + S     LP+P     PPT   G  P  S  P T T    T    T + P
Sbjct: 1945 TGTRTPVAHTTSASSSRLPTPFTTHSPPT---GSSPFSSTGPMTATSFQTTTTYPTPSHP 2001

Query: 426  QATSAPSPAPKQSFLFGTQNTSPSSPAA------PAASSASPMFKPIFTAPPKS--EKEG 477
            Q T+ P+  P     F T   +PS+           A+SAS    P  T PP +  +  G
Sbjct: 2002 Q-TTLPTHVPP----FSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVPPPTTLKATG 2056

Query: 478  PTPPGPSVTATAPSSSSLPTTTST--------TAPTFQPVFSSMGPPAS-VPLPAPFFKQ 528
             T   P +T T   +S   ++ ST        ++ ++ P  SS  PP+S +    P    
Sbjct: 2057 STHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSS 2116

Query: 529  TTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTS 588
             TTP +     +  F+   SA S V+    +S S+   S P+ G   + VS+   STT S
Sbjct: 2117 ATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLS 2176

Query: 589  TATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVT---------TFSQSLP 639
            + + +S   L   P  ++ S +P       F   PA  TT   T         T S  LP
Sbjct: 2177 SGSHSS---LSTHPTTASVSASPL------FPSSPAASTTIRATLPHTISSPFTLSALLP 2227

Query: 640  ----TAVPTATSSSAADFSGFGSTLAT-----SAPATSSQPTLTFS---NTSTPTFNIPF 687
                T  PT +S  A+    F ST  T     +APA SSQ T + S    T  PT     
Sbjct: 2228 ISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVS 2287

Query: 688  GSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPA 747
             +S  + +P+ P  N          + PG   P L+P    +  F  S+  A  + P  A
Sbjct: 2288 LTSGVTGIPTSPVTN-------LTTRHPG---PTLSP----TTRFLTSSLTAHGSTPASA 2333

Query: 748  PASTIKIVPAHVPTPIQP 765
            P S++       PTP  P
Sbjct: 2334 PVSSL-----GTPTPTSP 2346


>gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]
          Length = 2639

 Score =  118 bits (295), Expect = 3e-26
 Identities = 137/494 (27%), Positives = 196/494 (39%), Gaps = 74/494 (14%)

Query: 293  ASNSVTETPPTTQPSFTFTLPAAATASPPTSLLAPSTNPLLESLKKMQTP-PSLPPCPES 351
            ++ S T TP TT  + T T         PT    P+T P+  +     TP P+    P +
Sbjct: 1330 STQSTTPTPITTTTTVTPT-------PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1382

Query: 352  AGAATTEALSPPKTPS-----LLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMV 406
                TT  ++P  TP+        P+  + +  P   P+P+    P TT     P  +  
Sbjct: 1383 TPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTP--TPTPTGTQTPTTT-----PITTTT 1435

Query: 407  PATDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPI 466
              T T  P   QA T T    TS  +P P  +   GTQ  +P++      ++ +P   P 
Sbjct: 1436 TVTPTPTPTGTQAPTPTAITTTSTVTPTPTPT---GTQ--TPTTTPITTTTTVTPTPTPT 1490

Query: 467  FTAPPKSEKEGPT---PPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASV---- 519
             T  P       T    P P+ T T   +S+  TTT+T  PT  P  +    P  +    
Sbjct: 1491 GTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTT 1550

Query: 520  ---PLPAPFFKQ--TTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFG 574
               P P P   Q  TTTP T  TT  P  T   + T     IT+ +  T + +       
Sbjct: 1551 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTP------ 1604

Query: 575  INSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTF 634
              S  S++V+  T+T T  + P   G         TP M        P +  TT T T  
Sbjct: 1605 -TSTKSTTVTPITTTTTVTATPTPTGTQ-------TPTM-------IPISTTTTVTPTPT 1649

Query: 635  SQSLPTAVPTATSSS-AADFSGFGSTLATSAPAT--SSQPTLTFSNTSTPTFNIPFGSSA 691
              +  T  PT TS++  A+ +       +S P T  S+   LT S T   T       ++
Sbjct: 1650 PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 1709

Query: 692  KSPLPSYPGANPQPAFGAAEGQPPG-AAKPALTPSFGSSFTFGNSAAPAPAT-------- 742
             +P PS P A    + G     PP     P  TP+ G+  T G+S+AP P+T        
Sbjct: 1710 TAP-PSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGT--TTGSSSAPTPSTVQTTTTSA 1766

Query: 743  -APTPAPASTIKIV 755
              PTP P ST  I+
Sbjct: 1767 WTPTPTPLSTPSII 1780



 Score =  103 bits (258), Expect = 6e-22
 Identities = 138/565 (24%), Positives = 198/565 (35%), Gaps = 116/565 (20%)

Query: 400  IPAPSMVPATDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNTSPS--------SP 451
            +  P+ +  T T+ P      T T    T  P+P P       TQ+T+P+        +P
Sbjct: 1297 VTQPTTMTTTTTENPTPTPITTTT----TVTPTPTPTS-----TQSTTPTPITTTTTVTP 1347

Query: 452  AAPAASSASPMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSSSL-----PTTTSTTAPTF 506
                  + +P   PI T    +    PTP G     T P +++      PT T T  PT 
Sbjct: 1348 TPTPTGTQTPTTTPITTTTTVTPT--PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTS 1405

Query: 507  QPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSA 566
             P+ ++       P P P    T TP T P TT    T   + T   AP  +A  +T + 
Sbjct: 1406 TPITTTT---TVTPTPTP--TGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTV 1460

Query: 567  SKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALP 626
            +      G  + +++ + TTT+T T    P           + TP          P A+ 
Sbjct: 1461 TPTPTPTGTQTPTTTPI-TTTTTVTPTPTP---------TGTQTPT---------PTAIT 1501

Query: 627  TTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIP 686
            TTTTVT      PT  PT T +         ST  T+    +  PT T + T TPT    
Sbjct: 1502 TTTTVT------PTPTPTGTQTPT-------STPITTTTTVTPTPTPTGTQTPTPT---- 1544

Query: 687  FGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTP 746
                   P+ +     P P        P G   P  TP      T   +  P P    T 
Sbjct: 1545 -------PISTTTTVTPTPT-------PTGTQTPTTTP-----ITTTTTVTPTPTPTGTQ 1585

Query: 747  APAST-IKIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFGA 805
             P +  I       PTP   +    T +      T +A   P  +Q              
Sbjct: 1586 TPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQ-------------- 1631

Query: 806  ATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATTGAF 865
             T +    +T T  + + +   GST P   T     A   + +     +TP +S +T   
Sbjct: 1632 -TPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRST--- 1687

Query: 866  SFGAGQSGSTATSTPFTGGLGQNALGTTGQSTPFAFNVGSTTESKPVFGGTATPTFGQNT 925
                  S     ST     L   A+  T  + P      +TT      G T +P     T
Sbjct: 1688 ------SSPLTESTTLLSTL-PPAIEMTSTAPPSTPTAPTTTSG----GHTLSPPPSTTT 1736

Query: 926  PAPGVGTSGSSLSFGASSAPAQGFV 950
              PG  T G++   G+SSAP    V
Sbjct: 1737 SPPGTPTRGTTT--GSSSAPTPSTV 1759



 Score =  103 bits (258), Expect = 6e-22
 Identities = 143/611 (23%), Positives = 225/611 (36%), Gaps = 66/611 (10%)

Query: 347  PCPESAGAATTEALSPPKTPSLLP-PLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSM 405
            P P +     T   +P  T S  P P+  + +  P   P+P+    P TT     P  + 
Sbjct: 1313 PTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTP--TPTPTGTQTPTTT-----PITTT 1365

Query: 406  VPATDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKP 465
               T T  P   Q  T T    T+  +P P  +   GTQ  +P+S      ++ +P   P
Sbjct: 1366 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT---GTQ--TPTSTPITTTTTVTPTPTP 1420

Query: 466  IFTAPPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPF 525
              T  P       T P  + T   P+    PT T T APT   + ++     S   P P 
Sbjct: 1421 TGTQTPT------TTPITTTTTVTPT----PTPTGTQAPTPTAITTT-----STVTPTPT 1465

Query: 526  FKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVST 585
               T TP T P TT    T   + T    P  +A  +T + +      G  + +S+ + T
Sbjct: 1466 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPI-T 1524

Query: 586  TTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTA 645
            TT+T T    P     P  +  S T  + +          PTTT +TT +   PT  PT 
Sbjct: 1525 TTTTVTPTPTPTGTQTPTPTPISTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 1583

Query: 646  TSSSAADFSGFGSTLA-----TSAPATSSQP-TLTFSNTSTPTFNIPFGSSAKSPLPSYP 699
            T +         +T+      TS  +T+  P T T + T+TPT   P G+   + +P   
Sbjct: 1584 TQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPT---PTGTQTPTMIPI-- 1638

Query: 700  GANPQPAFGAAEGQPPGAAKPALTPSFGSSF--TFGNSAAPAPATAPTPAPASTIKIVPA 757
                                P  TP+ GS+   T  ++A  A  T   P P S+      
Sbjct: 1639 -------------STTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSR 1685

Query: 758  HVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAATSSGFGATTQT 817
               +P+  +    +     ++ T++A  +  ++     G   +    + T+S  G  T+ 
Sbjct: 1686 STSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRG 1745

Query: 818  ASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATTGAFSFGAGQSGSTAT 877
             ++GSSS+   ST  +  T   +  P         ++TP    TTG   + +        
Sbjct: 1746 TTTGSSSAPTPSTVQTTTTSAWTPTPT-------PLSTPSIIRTTGLRPYPSSVLICCVL 1798

Query: 878  STPFTGGLGQNALGTTGQSTPFAFNVGSTTESKPVFGGTATPTFGQNTPAPGVGTSGSSL 937
            +  +     +   GT G +  F   V  +      F   + P+    TP P   T   S 
Sbjct: 1799 NDTYYAPGEEVYNGTYGDTCYF---VNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSK 1855

Query: 938  SFGASSAPAQG 948
                 S P  G
Sbjct: 1856 PSSTPSKPTPG 1866



 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 68/245 (27%), Positives = 91/245 (37%), Gaps = 45/245 (18%)

Query: 292  AASNSVTETP-PTT----QPSFTFTLPAA--ATASPPTSLLAPSTN-----PLLESLKKM 339
            + + +VT TP PTT     P+ T T P A   T++PP     P T+     PL ES   +
Sbjct: 1639 STTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLL 1698

Query: 340  QTPPSLPPCPESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPP------ 393
             T   LPP  E    A      PP TP+       + SG   L P PS  + PP      
Sbjct: 1699 ST---LPPAIEMTSTA------PPSTPTA----PTTTSGGHTLSPPPSTTTSPPGTPTRG 1745

Query: 394  -TTLLGLIPAPSMVPATDTKA-PPTLQAETATKPQATSAPSPAPKQSFLFGTQNTSPSSP 451
             TT     P PS V  T T A  PT    +      T+   P P    +    N +  +P
Sbjct: 1746 TTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAP 1805

Query: 452  AAPAAS------------SASPMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSSSLPTTT 499
                 +            S S   +    + P +    PTP   + T + PSS+    T 
Sbjct: 1806 GEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTP 1865

Query: 500  STTAP 504
             T  P
Sbjct: 1866 GTKPP 1870



 Score = 39.3 bits (90), Expect = 0.018
 Identities = 78/381 (20%), Positives = 137/381 (35%), Gaps = 47/381 (12%)

Query: 126  SSSMSSLTGAYTSGIPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRSQTPER 185
            S+ +++ T    +  P+ ++    +  S+T  ++      G + +P ++P ++ +     
Sbjct: 1520 STPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTG-TQTPTTTPITTTTTVTPT 1578

Query: 186  PAKKIREEELCHHSSSSTPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQRKRKVQL 245
            P     +       +++T +         K+   TP     + + +TP  +G +     +
Sbjct: 1579 PTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVT-ATPTPTGTQTPT--M 1635

Query: 246  LPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETPPTTQ 305
            +P      +T  P P  G +           A L   N   E  +   S S T +P T  
Sbjct: 1636 IPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRS-TSSPLTES 1694

Query: 306  PSFTFTLPAA---ATASPPTSLLAPST----NPLLESLKKMQTPPSLP-----------P 347
             +   TLP A    + +PP++  AP+T    + L        +PP  P           P
Sbjct: 1695 TTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAP 1754

Query: 348  CPESAGAATTEALSPP----KTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAP 403
             P +    TT A +P      TPS++   GL       L+     D+          P  
Sbjct: 1755 TPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTY-------YAPGE 1807

Query: 404  SMVPAT--------DTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPA 455
             +   T        +     TL+    + P   S PSP P  S    T +   S+P+ P 
Sbjct: 1808 EVYNGTYGDTCYFVNCSLSCTLEFYNWSCP---STPSPTPTPSKSTPTPSKPSSTPSKPT 1864

Query: 456  ASSASPMFKPIFTAPPKSEKE 476
              +  P   P F  PP+ E E
Sbjct: 1865 PGTKPPEC-PDFD-PPRQENE 1883


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score =  117 bits (292), Expect = 7e-26
 Identities = 229/968 (23%), Positives = 331/968 (34%), Gaps = 147/968 (15%)

Query: 3   CSPVTVRIAPPDRRFSRSAIPEQIISSTLSSPSSNAPDPCAKETVLSALKEKKKKRTVEE 62
           C+ V    +PP    S+ A P    S T+ S +  +P P            KKK + V E
Sbjct: 63  CAEVHNPTSPPS---SKKAPPPSGASQTIKSTTKRSPKP----------PNKKKTKKVIE 109

Query: 63  EDQIFLDGQENKRRRHDSSGSGHSAFEPLVASGVPASFVPKPGSLKRGLNSQSSDDHL-- 120
            ++I  +   ++ +   SS S  S+          +S + K  S K    ++     L  
Sbjct: 110 SEEITEEHSVSENQESSSSSSSSSS----------SSTIRKIKSSKNSAANRELQKKLKV 159

Query: 121 --NKRSRSSSMSS----LTGAYTSGIPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSS 174
             NK++R+    +    +     SG+ +      T   S+T+        N  S+SP  +
Sbjct: 160 KDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQ-------HNKVSTSPKIT 212

Query: 175 PASSRSQTPERPAKKIREEELCHHSSSSTPLAADKESQGEKAADTTPRKKQNSNSQ--ST 232
            A   +  P  P            +S  T L  +KE+  E    TT  K+ +++ +  +T
Sbjct: 213 TAKPINPRPSLPPNS--------DTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTT 264

Query: 233 PGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDA 292
                Q   K          ++   P P+   +     L   K+ +            + 
Sbjct: 265 SAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPT-------TPKEP 317

Query: 293 ASNSVTETPPTTQPSFTFTLPAAA---TASPPTSLLAPSTNPLLESLKKMQTPPSLPPCP 349
           AS +  E  PTT  S   T    A   T S PT+   P+     E        P+     
Sbjct: 318 ASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTK 377

Query: 350 ESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKP-PTTLLGLIPAPSMVPA 408
           E A   T  A + PK P+   P            P+P+   +P PTT     P     PA
Sbjct: 378 EPAPTTTKSAPTTPKEPAPTTPKK----------PAPTTPKEPAPTTPKEPTPTTPKEPA 427

Query: 409 TDTKAP-PTLQAETAT----KPQATSAPSPAP---KQSFLFGTQNTSPSSPAAPAASSAS 460
             TK P PT   E A     KP  T+   PAP   K+     T+  SP++P  PA ++  
Sbjct: 428 PTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTK 487

Query: 461 PMFKPIFTAPPKSEKEGPTPPG-PSVTAT---APSSSS--LPTTTSTTAPTFQ----PVF 510
                     P + K  PT P  PS T T   AP++     PTT    APT      P  
Sbjct: 488 SAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTT 547

Query: 511 SSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSA--VAPIT--SASPSTDSA 566
                P +   PAP   +   P T P  TAP      + T+   +AP T    +P+T   
Sbjct: 548 PKEPAPTTTKKPAPTTPKEPAPTT-PKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEE 606

Query: 567 SKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKP-PAL 625
             P         +    + TT  A A + P          A  TP   +     +P P  
Sbjct: 607 LAPTTPEEPTPTTPEEPAPTTPKAAAPNTP-------KEPAPTTPKEPAPTTPKEPAPTT 659

Query: 626 PTTTTVTTFSQSLPTAV----PTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTP 681
           P  T  TT   + PT +    PT     A             AP T+ +PT T  +   P
Sbjct: 660 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPK---------ELAPTTTKEPTSTTCDKPAP 710

Query: 682 TF---------NIPFGSSAKSPLPSYP-GANPQPAFGAAEGQPPGAAKPALTPSFGSSFT 731
           T            P  ++ K P P+ P G  P      A   P   A   L P+     T
Sbjct: 711 TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPT 770

Query: 732 FGNSAAPAPATA----PT----PAPASTIKIVPAHVPTPIQPTFGGATHSAFGLKATASA 783
              S  PAP T     PT    PAP +  K  P    TP   T   +T +    K   + 
Sbjct: 771 STTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTT--TKEPTTI 828

Query: 784 FGAPASSQPAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAP 843
             +P  S P         +   +       TT+T ++        +TT    T       
Sbjct: 829 HKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEM---TTTAKDKTTERDLRT 885

Query: 844 AGSGSFGINVATPGSSATTGAFSFGAGQSGSTATSTPFTGGLGQNALGTTGQSTPFAFNV 903
                     A P  +  T   +    +S  TAT+T  T         TT  +TPF    
Sbjct: 886 TPE----TTTAAPKMTKETATTTEKTTESKITATTTQVTS-------TTTQDTTPFKITT 934

Query: 904 GSTTESKP 911
             TT   P
Sbjct: 935 LKTTTLAP 942



 Score =  101 bits (251), Expect = 4e-21
 Identities = 180/798 (22%), Positives = 259/798 (32%), Gaps = 135/798 (16%)

Query: 167 PSSSPFSSPASSRSQT--------PERPAKK-----IREEELCHHSSSSTPLAADKESQG 213
           P SS  + P S  SQT        P+ P KK     I  EE+    S S    +   S  
Sbjct: 72  PPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSS 131

Query: 214 EKAADTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDL 273
             ++ T  + K + NS +      Q+K KV+     R ++   P PP             
Sbjct: 132 SSSSSTIRKIKSSKNSAAN--RELQKKLKVKDNKKNRTKKKPTPKPP------------- 176

Query: 274 EKKASLQWFNQALEDKSDAASNSVTETPPTTQPSFTFTLPAAATASPPTSLLAPSTNPLL 333
                       +++      N            F  T P  +T    T     ST+P +
Sbjct: 177 -----------VVDEAGSGLDNG----------DFKVTTPDTST----TQHNKVSTSPKI 211

Query: 334 ESLKKMQTPPSLPPCPESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPP 393
            + K +   PSLPP  +++   +          +        Q+   G        S   
Sbjct: 212 TTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDG---KEKTTSAKE 268

Query: 394 TTLLGLIPAPSMVPATDTKAPPTLQAETATK-PQATSAPSPAPKQSFLFGTQNTSPSSPA 452
           T  +    A  + P +   A PT +AET TK P  T+   P P          T+P  PA
Sbjct: 269 TQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTP----------TTPKEPA 318

Query: 453 APAASSASPMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSS 512
           +      +P          KS    P  P P+ T +AP++   P  T+T  P        
Sbjct: 319 STTPKEPTP-------TTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPA------- 364

Query: 513 MGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFG 572
              P +   PAP    TTT   APTTT              AP T   P+  +  KPA  
Sbjct: 365 ---PTTPKEPAP----TTTKEPAPTTTKS------------APTTPKEPAPTTPKKPA-- 403

Query: 573 FGINSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKP-PALPTTTTV 631
                 +    + TT      + P          A  TP   +     KP P  P     
Sbjct: 404 ----PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAP 459

Query: 632 TTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSA 691
           TT  +  PT     + ++  + +    T   SAP T+ +P  T + ++  T   P  ++ 
Sbjct: 460 TTPKEPAPTTTKEPSPTTPKEPA---PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTT 516

Query: 692 KSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPAST 751
           K P P+ P           E  P    KPA T              PAP T   PAP +T
Sbjct: 517 KEPAPTTP----------KEPAPTTPKKPAPT----------TPKEPAPTTPKEPAPTTT 556

Query: 752 IKIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAATSSGF 811
            K  P   P    PT    T      K T +     A + P     T        T    
Sbjct: 557 KKPAPT-TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP 615

Query: 812 GATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATTGAFSFGAGQ 871
             TT    + ++       TP          PA +        TP  +A T         
Sbjct: 616 TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTT 675

Query: 872 SGSTATSTPFTGGLGQNALGTTGQSTPFAFNVGSTTESKPVFGGT----ATPTFGQNTPA 927
               A +TP      + A  TT + T    +  + T  K     T    A  T  +  P 
Sbjct: 676 LKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPT 735

Query: 928 PGVGTSGSSLSFGASSAP 945
              GT+ ++L   A + P
Sbjct: 736 TPKGTAPTTLKEPAPTTP 753



 Score = 83.2 bits (204), Expect = 1e-15
 Identities = 136/611 (22%), Positives = 222/611 (36%), Gaps = 65/611 (10%)

Query: 141  PSSSRNAITSSY----SSTRGISQLWKRNGPSSSPFSSPASSRSQ---TPERPAKKIREE 193
            P+++++A T++     ++T+      K   P+++   +P + +     TP++PA    +E
Sbjct: 483  PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKE 542

Query: 194  ELCHHSSSSTPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQ 253
                      P         +K A TTP++   +  + T  ++ ++      L     E+
Sbjct: 543  PAPTTPKEPAPTTT------KKPAPTTPKEPAPTTPKETAPTTPKK------LTPTTPEK 590

Query: 254  LTLPPPPQLGYSITAEDL---DLEKKASLQWFNQALEDKSDAASNSVTETPPTTQPSFTF 310
            L  P  P+     T E+L     E+         A      AA N+  E  PTT      
Sbjct: 591  LA-PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAP 649

Query: 311  TLPAAATASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALSPPKT----P 366
            T P     + P    AP+T          +  P+ P  P     A T    P  T    P
Sbjct: 650  TTPKEPAPTTPKET-APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKP 708

Query: 367  SLLPPLGLSQSGPPGLLPSPSFDSKP-PTTLLGLIPAPSMVPATDTK---APPTLQAETA 422
            +   P G + + P    P+P+   +P PTT  G  P     PA  T    AP  L   T 
Sbjct: 709  APTTPKGTAPTTPKE--PAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT 766

Query: 423  TKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPPG 482
              P +T++  PAP        + T+P++P  PA ++           PP +  E  TP  
Sbjct: 767  KGPTSTTSDKPAPTTP-----KETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTT 821

Query: 483  PSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPA--SVPLPAPFFKQTTTPATAPTTTA 540
                 T   S    T   +  PT + + +S   P   +   PA    + TT A   TT  
Sbjct: 822  TKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTER 881

Query: 541  PLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFG 600
             L T   + T+A       + +T+  ++        S  +++ +  TST T  + PF   
Sbjct: 882  DLRTTPETTTAAPKMTKETATTTEKTTE--------SKITATTTQVTSTTTQDTTPFKIT 933

Query: 601  -------APQASAA----SFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSS 649
                   AP+ +      + T  M    +  KP    T +  TT     PT  P   +S+
Sbjct: 934  TLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTST 993

Query: 650  AADFS----GFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQP 705
                +        T  T    TS+ P L  ++              ++P       NP+ 
Sbjct: 994  KKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKS 1053

Query: 706  A-FGAAEGQPP 715
               G AEG+ P
Sbjct: 1054 EDAGGAEGETP 1064



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 116/535 (21%), Positives = 174/535 (32%), Gaps = 104/535 (19%)

Query: 348 CP--ESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSM 405
           CP  ES  A      SPP +    PP G SQ+       SP    KPP            
Sbjct: 56  CPDYESFCAEVHNPTSPPSSKKAPPPSGASQTIKSTTKRSP----KPP------------ 99

Query: 406 VPATDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKP 465
                 K    +++E  T+  + S    +   S    + +T     ++  +++   + K 
Sbjct: 100 ---NKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKK 156

Query: 466 IFTAPPKSE--KEGPTPPGPSV------------TATAPSSSSLPTTTSTTAPTFQPVFS 511
           +     K    K+ PTP  P V              T P +S+      +T+P       
Sbjct: 157 LKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTA-K 215

Query: 512 SMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAF 571
            + P  S+P  +   K+T+      TT     T            T+   STD   K   
Sbjct: 216 PINPRPSLPPNSDTSKETSLTVNKETTVETKET----------TTTNKQTSTDGKEKTTS 265

Query: 572 GFGINSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTV 631
                S+  +S      T+   ++P     P+A   +  PA+ +       P  PT TT 
Sbjct: 266 AKETQSIEKTSAKDLAPTSKVLAKP----TPKAETTTKGPALTT-------PKEPTPTTP 314

Query: 632 TTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSA 691
              + + P   PT T+               SAP T  +P  T + ++  T   P  ++ 
Sbjct: 315 KEPASTTPKE-PTPTT-------------IKSAPTTPKEPAPTTTKSAPTTPKEPAPTTT 360

Query: 692 KSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPAST 751
           K P P+ P    +PA    +   P   K A T              PAP T   PAP + 
Sbjct: 361 KEPAPTTP---KEPAPTTTKEPAPTTTKSAPT----------TPKEPAPTTPKKPAPTTP 407

Query: 752 IKIVPA--HVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAATSS 809
            +  P     PTP  P            K  A     PA + P     TA       T  
Sbjct: 408 KEPAPTTPKEPTPTTP------------KEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPK 455

Query: 810 GFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATTGA 864
               TT    + +++     TTP         AP  + S       P  + T  A
Sbjct: 456 EPAPTTPKEPAPTTTKEPSPTTPK------EPAPTTTKSAPTTTKEPAPTTTKSA 504


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score =  117 bits (292), Expect = 7e-26
 Identities = 229/968 (23%), Positives = 331/968 (34%), Gaps = 147/968 (15%)

Query: 3   CSPVTVRIAPPDRRFSRSAIPEQIISSTLSSPSSNAPDPCAKETVLSALKEKKKKRTVEE 62
           C+ V    +PP    S+ A P    S T+ S +  +P P            KKK + V E
Sbjct: 104 CAEVHNPTSPPS---SKKAPPPSGASQTIKSTTKRSPKP----------PNKKKTKKVIE 150

Query: 63  EDQIFLDGQENKRRRHDSSGSGHSAFEPLVASGVPASFVPKPGSLKRGLNSQSSDDHL-- 120
            ++I  +   ++ +   SS S  S+          +S + K  S K    ++     L  
Sbjct: 151 SEEITEEHSVSENQESSSSSSSSSS----------SSTIRKIKSSKNSAANRELQKKLKV 200

Query: 121 --NKRSRSSSMSS----LTGAYTSGIPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSS 174
             NK++R+    +    +     SG+ +      T   S+T+        N  S+SP  +
Sbjct: 201 KDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQ-------HNKVSTSPKIT 253

Query: 175 PASSRSQTPERPAKKIREEELCHHSSSSTPLAADKESQGEKAADTTPRKKQNSNSQ--ST 232
            A   +  P  P            +S  T L  +KE+  E    TT  K+ +++ +  +T
Sbjct: 254 TAKPINPRPSLPPNS--------DTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTT 305

Query: 233 PGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDA 292
                Q   K          ++   P P+   +     L   K+ +            + 
Sbjct: 306 SAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPT-------TPKEP 358

Query: 293 ASNSVTETPPTTQPSFTFTLPAAA---TASPPTSLLAPSTNPLLESLKKMQTPPSLPPCP 349
           AS +  E  PTT  S   T    A   T S PT+   P+     E        P+     
Sbjct: 359 ASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTK 418

Query: 350 ESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKP-PTTLLGLIPAPSMVPA 408
           E A   T  A + PK P+   P            P+P+   +P PTT     P     PA
Sbjct: 419 EPAPTTTKSAPTTPKEPAPTTPKK----------PAPTTPKEPAPTTPKEPTPTTPKEPA 468

Query: 409 TDTKAP-PTLQAETAT----KPQATSAPSPAP---KQSFLFGTQNTSPSSPAAPAASSAS 460
             TK P PT   E A     KP  T+   PAP   K+     T+  SP++P  PA ++  
Sbjct: 469 PTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTK 528

Query: 461 PMFKPIFTAPPKSEKEGPTPPG-PSVTAT---APSSSS--LPTTTSTTAPTFQ----PVF 510
                     P + K  PT P  PS T T   AP++     PTT    APT      P  
Sbjct: 529 SAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTT 588

Query: 511 SSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSA--VAPIT--SASPSTDSA 566
                P +   PAP   +   P T P  TAP      + T+   +AP T    +P+T   
Sbjct: 589 PKEPAPTTTKKPAPTTPKEPAPTT-PKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEE 647

Query: 567 SKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKP-PAL 625
             P         +    + TT  A A + P          A  TP   +     +P P  
Sbjct: 648 LAPTTPEEPTPTTPEEPAPTTPKAAAPNTP-------KEPAPTTPKEPAPTTPKEPAPTT 700

Query: 626 PTTTTVTTFSQSLPTAV----PTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTP 681
           P  T  TT   + PT +    PT     A             AP T+ +PT T  +   P
Sbjct: 701 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPK---------ELAPTTTKEPTSTTCDKPAP 751

Query: 682 TF---------NIPFGSSAKSPLPSYP-GANPQPAFGAAEGQPPGAAKPALTPSFGSSFT 731
           T            P  ++ K P P+ P G  P      A   P   A   L P+     T
Sbjct: 752 TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPT 811

Query: 732 FGNSAAPAPATA----PT----PAPASTIKIVPAHVPTPIQPTFGGATHSAFGLKATASA 783
              S  PAP T     PT    PAP +  K  P    TP   T   +T +    K   + 
Sbjct: 812 STTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTT--TKEPTTI 869

Query: 784 FGAPASSQPAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAP 843
             +P  S P         +   +       TT+T ++        +TT    T       
Sbjct: 870 HKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEM---TTTAKDKTTERDLRT 926

Query: 844 AGSGSFGINVATPGSSATTGAFSFGAGQSGSTATSTPFTGGLGQNALGTTGQSTPFAFNV 903
                     A P  +  T   +    +S  TAT+T  T         TT  +TPF    
Sbjct: 927 TPE----TTTAAPKMTKETATTTEKTTESKITATTTQVTS-------TTTQDTTPFKITT 975

Query: 904 GSTTESKP 911
             TT   P
Sbjct: 976 LKTTTLAP 983



 Score =  101 bits (251), Expect = 4e-21
 Identities = 180/798 (22%), Positives = 259/798 (32%), Gaps = 135/798 (16%)

Query: 167 PSSSPFSSPASSRSQT--------PERPAKK-----IREEELCHHSSSSTPLAADKESQG 213
           P SS  + P S  SQT        P+ P KK     I  EE+    S S    +   S  
Sbjct: 113 PPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSS 172

Query: 214 EKAADTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDL 273
             ++ T  + K + NS +      Q+K KV+     R ++   P PP             
Sbjct: 173 SSSSSTIRKIKSSKNSAAN--RELQKKLKVKDNKKNRTKKKPTPKPP------------- 217

Query: 274 EKKASLQWFNQALEDKSDAASNSVTETPPTTQPSFTFTLPAAATASPPTSLLAPSTNPLL 333
                       +++      N            F  T P  +T    T     ST+P +
Sbjct: 218 -----------VVDEAGSGLDNG----------DFKVTTPDTST----TQHNKVSTSPKI 252

Query: 334 ESLKKMQTPPSLPPCPESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPP 393
            + K +   PSLPP  +++   +          +        Q+   G        S   
Sbjct: 253 TTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDG---KEKTTSAKE 309

Query: 394 TTLLGLIPAPSMVPATDTKAPPTLQAETATK-PQATSAPSPAPKQSFLFGTQNTSPSSPA 452
           T  +    A  + P +   A PT +AET TK P  T+   P P          T+P  PA
Sbjct: 310 TQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTP----------TTPKEPA 359

Query: 453 APAASSASPMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSS 512
           +      +P          KS    P  P P+ T +AP++   P  T+T  P        
Sbjct: 360 STTPKEPTP-------TTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPA------- 405

Query: 513 MGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFG 572
              P +   PAP    TTT   APTTT              AP T   P+  +  KPA  
Sbjct: 406 ---PTTPKEPAP----TTTKEPAPTTTKS------------APTTPKEPAPTTPKKPA-- 444

Query: 573 FGINSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKP-PALPTTTTV 631
                 +    + TT      + P          A  TP   +     KP P  P     
Sbjct: 445 ----PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAP 500

Query: 632 TTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSA 691
           TT  +  PT     + ++  + +    T   SAP T+ +P  T + ++  T   P  ++ 
Sbjct: 501 TTPKEPAPTTTKEPSPTTPKEPA---PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTT 557

Query: 692 KSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPAST 751
           K P P+ P           E  P    KPA T              PAP T   PAP +T
Sbjct: 558 KEPAPTTP----------KEPAPTTPKKPAPT----------TPKEPAPTTPKEPAPTTT 597

Query: 752 IKIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAATSSGF 811
            K  P   P    PT    T      K T +     A + P     T        T    
Sbjct: 598 KKPAPT-TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP 656

Query: 812 GATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATTGAFSFGAGQ 871
             TT    + ++       TP          PA +        TP  +A T         
Sbjct: 657 TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTT 716

Query: 872 SGSTATSTPFTGGLGQNALGTTGQSTPFAFNVGSTTESKPVFGGT----ATPTFGQNTPA 927
               A +TP      + A  TT + T    +  + T  K     T    A  T  +  P 
Sbjct: 717 LKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPT 776

Query: 928 PGVGTSGSSLSFGASSAP 945
              GT+ ++L   A + P
Sbjct: 777 TPKGTAPTTLKEPAPTTP 794



 Score = 83.2 bits (204), Expect = 1e-15
 Identities = 136/611 (22%), Positives = 222/611 (36%), Gaps = 65/611 (10%)

Query: 141  PSSSRNAITSSY----SSTRGISQLWKRNGPSSSPFSSPASSRSQ---TPERPAKKIREE 193
            P+++++A T++     ++T+      K   P+++   +P + +     TP++PA    +E
Sbjct: 524  PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKE 583

Query: 194  ELCHHSSSSTPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQ 253
                      P         +K A TTP++   +  + T  ++ ++      L     E+
Sbjct: 584  PAPTTPKEPAPTTT------KKPAPTTPKEPAPTTPKETAPTTPKK------LTPTTPEK 631

Query: 254  LTLPPPPQLGYSITAEDL---DLEKKASLQWFNQALEDKSDAASNSVTETPPTTQPSFTF 310
            L  P  P+     T E+L     E+         A      AA N+  E  PTT      
Sbjct: 632  LA-PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAP 690

Query: 311  TLPAAATASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALSPPKT----P 366
            T P     + P    AP+T          +  P+ P  P     A T    P  T    P
Sbjct: 691  TTPKEPAPTTPKET-APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKP 749

Query: 367  SLLPPLGLSQSGPPGLLPSPSFDSKP-PTTLLGLIPAPSMVPATDTK---APPTLQAETA 422
            +   P G + + P    P+P+   +P PTT  G  P     PA  T    AP  L   T 
Sbjct: 750  APTTPKGTAPTTPKE--PAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT 807

Query: 423  TKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPPG 482
              P +T++  PAP        + T+P++P  PA ++           PP +  E  TP  
Sbjct: 808  KGPTSTTSDKPAPTTP-----KETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTT 862

Query: 483  PSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPA--SVPLPAPFFKQTTTPATAPTTTA 540
                 T   S    T   +  PT + + +S   P   +   PA    + TT A   TT  
Sbjct: 863  TKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTER 922

Query: 541  PLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFG 600
             L T   + T+A       + +T+  ++        S  +++ +  TST T  + PF   
Sbjct: 923  DLRTTPETTTAAPKMTKETATTTEKTTE--------SKITATTTQVTSTTTQDTTPFKIT 974

Query: 601  -------APQASAA----SFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSS 649
                   AP+ +      + T  M    +  KP    T +  TT     PT  P   +S+
Sbjct: 975  TLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTST 1034

Query: 650  AADFS----GFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQP 705
                +        T  T    TS+ P L  ++              ++P       NP+ 
Sbjct: 1035 KKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKS 1094

Query: 706  A-FGAAEGQPP 715
               G AEG+ P
Sbjct: 1095 EDAGGAEGETP 1105



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 116/535 (21%), Positives = 174/535 (32%), Gaps = 104/535 (19%)

Query: 348 CP--ESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSM 405
           CP  ES  A      SPP +    PP G SQ+       SP    KPP            
Sbjct: 97  CPDYESFCAEVHNPTSPPSSKKAPPPSGASQTIKSTTKRSP----KPP------------ 140

Query: 406 VPATDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKP 465
                 K    +++E  T+  + S    +   S    + +T     ++  +++   + K 
Sbjct: 141 ---NKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKK 197

Query: 466 IFTAPPKSE--KEGPTPPGPSV------------TATAPSSSSLPTTTSTTAPTFQPVFS 511
           +     K    K+ PTP  P V              T P +S+      +T+P       
Sbjct: 198 LKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTA-K 256

Query: 512 SMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAF 571
            + P  S+P  +   K+T+      TT     T            T+   STD   K   
Sbjct: 257 PINPRPSLPPNSDTSKETSLTVNKETTVETKET----------TTTNKQTSTDGKEKTTS 306

Query: 572 GFGINSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTV 631
                S+  +S      T+   ++P     P+A   +  PA+ +       P  PT TT 
Sbjct: 307 AKETQSIEKTSAKDLAPTSKVLAKP----TPKAETTTKGPALTT-------PKEPTPTTP 355

Query: 632 TTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSA 691
              + + P   PT T+               SAP T  +P  T + ++  T   P  ++ 
Sbjct: 356 KEPASTTPKE-PTPTT-------------IKSAPTTPKEPAPTTTKSAPTTPKEPAPTTT 401

Query: 692 KSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPAST 751
           K P P+ P    +PA    +   P   K A T              PAP T   PAP + 
Sbjct: 402 KEPAPTTP---KEPAPTTTKEPAPTTTKSAPT----------TPKEPAPTTPKKPAPTTP 448

Query: 752 IKIVPA--HVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAATSS 809
            +  P     PTP  P            K  A     PA + P     TA       T  
Sbjct: 449 KEPAPTTPKEPTPTTP------------KEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPK 496

Query: 810 GFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATTGA 864
               TT    + +++     TTP         AP  + S       P  + T  A
Sbjct: 497 EPAPTTPKEPAPTTTKEPSPTTPK------EPAPTTTKSAPTTTKEPAPTTTKSA 545


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 1124

 Score =  116 bits (290), Expect = 1e-25
 Identities = 225/981 (22%), Positives = 339/981 (34%), Gaps = 172/981 (17%)

Query: 92   VASGVPASFVPKPGSL-KRGLNSQSSDDHLNKRS----RSSSMSSLTGAYTSGIPSSSRN 146
            V+S   AS   +PG L ++GL   + +     ++    + S++S+     TSG    + +
Sbjct: 114  VSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPS 173

Query: 147  AITSSYSSTRGISQLWKRNGPSSSPFSSPASSRSQTPERPAKKIREEELCHHSSSSTPLA 206
               +  S   G      R  PS+ P         + P    +K       H ++  +P A
Sbjct: 174  PAMARRSRAAGTEVGLPRPAPSARP---------RPPTEGPRKSVSSASEHSTTEPSPAA 224

Query: 207  ADKESQGEKAADTTPRKKQNSNSQ-STPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYS 265
              + S G        R   +S +  S+P  SG   R     P+   +     P P+   +
Sbjct: 225  RRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQ-----PKPKGLQA 279

Query: 266  ITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETPPTTQPSFTFT-LPAAATASPPTSL 324
            +    +   +K +               S S T+  P   P    T LPA    SPP + 
Sbjct: 280  LRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLAT 339

Query: 325  ---LAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALSPPKTPSLLPPLGLSQSGPPG 381
               LAP +     SL+ + +PP+ PP  ++  + TT  +  P +   +PP+ +  S    
Sbjct: 340  PLPLAPPSPSAPPSLQTLPSPPATPPS-QAPPSMTTPPMQAPPSLQTIPPIQVPHS---- 394

Query: 382  LLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQA----------ETATKPQATSAP 431
             L SPS  + PP+ L     A S + AT +   PTLQA          +T     + S P
Sbjct: 395  -LTSPSLQA-PPSPL-----ALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRP 447

Query: 432  SPAPKQSFLFGTQNTSPSSPAAPAASS--ASPMFKPIFTAPPKS-------EKEGPT--- 479
            +  P  S       + P+SP    + S   SP+  P+   P ++         + P    
Sbjct: 448  ASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSL 507

Query: 480  --PPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPP----ASVPLPAPFFKQTTTPA 533
              PP  + ++ AP S   P  + TT P       S+ PP    AS PL  P  +    PA
Sbjct: 508  IMPPLETQSSLAPPSLQTPPASLTTPPLEN--LPSLAPPPLQTASAPLTTPHLETPPCPA 565

Query: 534  T-------APTTTAPLFTGLASATSAV-APITSASPSTDSASKPAFGFGINSVSSSSVST 585
                    +P TT P  T  + AT    AP   ASP       P                
Sbjct: 566  PCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPL-------------- 611

Query: 586  TTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAV--- 642
                      P     PQA      P + +      PPA P  + + T S   P A+   
Sbjct: 612  ---------SPLATPPPQAPPXLALPPLQAP---PSPPASPPLSPLATPSPQAPNALAVH 659

Query: 643  ----PTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSY 698
                P +   S    + F    +     +++ P+    + + P   +P    A  P+   
Sbjct: 660  LLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMS-- 717

Query: 699  PGANPQPAFGAAEGQPPGAAKP-ALTPSFGSSFTFGNSAAPAPATAP---------TPAP 748
            P A P P     +  PP AA P  + PS  +S     SA P P   P          P+P
Sbjct: 718  PSATPPP-----QAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSP 772

Query: 749  ASTIKIVPAHVPTPIQPTF-----------------GGATHSAFGLKATASAFGAPASSQ 791
             +++ + P   P P  P                   G A  S       +     P  + 
Sbjct: 773  PASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAP 832

Query: 792  PAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGS--- 848
            P               S    A  +  + G  +SV G         G    P+ S S   
Sbjct: 833  PVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTL 892

Query: 849  FGINVATPGSSATT---GAFSFGAGQSGSTATSTPFTGGLG--QNALGTTGQSTPFAFN- 902
             G ++A   SSAT+       + +G  G  A S P    L     A  + G + P AF  
Sbjct: 893  SGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRG 952

Query: 903  -VGSTTESKPVFG----------------GTATPTFGQNTPAPGVGTSGSSLSFGA---- 941
              G+     P  G                 +ATP  G   P P  GTSG   + GA    
Sbjct: 953  APGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGA 1012

Query: 942  -SSAPAQGFVGVGPFGSAAPS 961
             S +P Q  +G  P G+   S
Sbjct: 1013 SSRSPKQARLGELPLGALQAS 1033



 Score = 89.0 bits (219), Expect = 2e-17
 Identities = 143/593 (24%), Positives = 206/593 (34%), Gaps = 109/593 (18%)

Query: 202 STPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQ 261
           S P A    S G  + +   R   +   +  P +       V   P R        P  Q
Sbjct: 73  SAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSS-PGRASGTTRPGPLGQ 131

Query: 262 LGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETPPTTQPSFTFTLPAAATA--- 318
            G  I+AE+     KA+      AL   + A  ++   TP T  P+      AA T    
Sbjct: 132 KGLRISAEETVARGKATEAPKRSALS--AGARRDTSGPTPGTPSPAMARRSRAAGTEVGL 189

Query: 319 --SPPTSLLAPSTNPLLESLKKMQTPPSLPPCPE-----SAGAATTEALSPPKTPSLLPP 371
               P++   P T    +S+       +  P P      SAG       S   + S  P 
Sbjct: 190 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL 249

Query: 372 LGLSQSGPP--GLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAETATKPQATS 429
              ++SGP   G   +P+  S+P    L  +  P + P     AP       ++ P AT 
Sbjct: 250 SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL--GPLSSSPLATP 307

Query: 430 APSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPPGPSVTATA 489
           +PS         GT+    + P  P  ++A+P+     T PP      P P  P   +  
Sbjct: 308 SPS---------GTK----ARPVPPPDNAATPL---PATLPPSPPLATPLPLAPPSPSAP 351

Query: 490 PSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASA 549
           PS  +LP+                 PPA+ P  AP    TT P  AP +       L + 
Sbjct: 352 PSLQTLPS-----------------PPATPPSQAP-PSMTTPPMQAPPS-------LQTI 386

Query: 550 TSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTAT---AASQPFLFGAPQASA 606
                P +  SPS  +   P        ++ SS+  TTS  +    A+  FL  +P+ + 
Sbjct: 387 PPIQVPHSLTSPSLQAPPSP--------LALSSLQATTSLGSPTLQATHSFLTMSPRQTQ 438

Query: 607 ASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTL------ 660
           AS T          +P + P  +       SLP + P  TS S A  S   S L      
Sbjct: 439 ASLTSP-------SRPASTPPDSPPLQAPLSLPASPPLQTSLSPA-VSPLSSPLTIHPLQ 490

Query: 661 --------ATSAPATS--SQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAA 710
                   +  AP +S    P  T S+ + P+   P  S    PL + P   P P     
Sbjct: 491 ALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPL---- 546

Query: 711 EGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVPAHVPTPI 763
                 A+ P  TP             P PA  P  AP S +   P   P+ I
Sbjct: 547 ----QTASAPLTTPHL--------ETPPCPAPCPLQAPPSPLTTPPPETPSSI 587


>gi|161019170 mucin 5AC [Homo sapiens]
          Length = 6207

 Score =  110 bits (274), Expect = 8e-24
 Identities = 156/570 (27%), Positives = 218/570 (38%), Gaps = 71/570 (12%)

Query: 331  PLLESLKKMQTPPSLPPCPESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDS 390
            P   +     TP S P         TT A +   T S   P     S  PG  P P   +
Sbjct: 3555 PSTPATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIP-----SSTPGTAPPPKVLT 3609

Query: 391  KPPTTLLGLIPAPSMVPATDTKAPPT-----LQAETATKPQATSAPSPAPKQSFLFGTQN 445
               TT     P  +   AT + +P T     +   TATK  ATS     P  SF  GT  
Sbjct: 3610 STATT-----PTATSSKATSSSSPRTATTLPVLTSTATKSTATSF---TPIPSFTLGTTG 3661

Query: 446  TSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPT 505
            T P     P A+ +        T  P S  E           T  +S+ L T  +TT  T
Sbjct: 3662 TLPEQTTTPMATMS--------TIHPSSTPE-----------TTHTSTVLTTKATTTRAT 3702

Query: 506  FQPVFSSMGPPASVP-----LPAPFFKQTTTPATAPTTT---APLFTGLASATSAVAPIT 557
                 SSM  P+S P     L       TTT AT PT T    P  T + +  S  A +T
Sbjct: 3703 -----SSMSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTEPSTTATVT 3757

Query: 558  SASPSTDSASKPAFGFGINSVSSSSVSTTT---STATAASQPFLFGA-PQASAASFTPAM 613
              + ST +AS      G   V +S+ +T T   S AT +S P    A P   + + TP  
Sbjct: 3758 VPTGSTATASSTRATAGTLKVLTSTATTPTVISSRATPSSSPGTATALPALRSTATTPTA 3817

Query: 614  GSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTL 673
             S+       A+P+++  T +++   T  PTAT S+A   S   +   ++   T++  T 
Sbjct: 3818 TSV------TAIPSSSLGTAWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTTTTTR 3871

Query: 674  TFSNTSTPTFNIPFGSSAKSPLPSYPG--ANPQPAFGAAEGQPPGAAKPALTPSFGSSFT 731
               + +TP+       + K P  +  G  A P  + G A   PP       TP+   S T
Sbjct: 3872 ATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTAL-TPPVWISTTTTPTTRGS-T 3929

Query: 732  FGNSAAPAPATAPTPAPASTIKIVPAHVPTPIQPT-FGGATHSAFGLKATASAFGAPASS 790
               S+ P      T    +T  +    + TP   T   G TH+      TA+  G    S
Sbjct: 3930 VTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTTATTHG---RS 3986

Query: 791  QPAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFG 850
             P     T   ++ +ATS   G T  T  S  +S    +TT +  T   + A +      
Sbjct: 3987 LPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTPAATTST--TQHSTPALSSPHPSS 4044

Query: 851  INVATPGSSATTGAFSFGAGQSGSTATSTP 880
                +P S  TT       G S +TAT+TP
Sbjct: 4045 RTTESPPSPGTTTP-GHTRGTSRTTATATP 4073



 Score =  105 bits (263), Expect = 2e-22
 Identities = 203/884 (22%), Positives = 312/884 (35%), Gaps = 134/884 (15%)

Query: 135  AYTSGIPSSSRNAITSSYSSTRGISQ---LW--KRNGPSSSPFSSPASSRSQTPERPAKK 189
            A+T+ +P+++    T + SS+ G ++   +W      P++S  +   SS   T   P   
Sbjct: 4388 AHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVL 4447

Query: 190  IREEELCHHSSSSTPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSR 249
                      S +TP ++  ++ G       P     ++ +S   SS    R      + 
Sbjct: 4448 TTTTTTVATGSMATP-SSSTQTSGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATS 4506

Query: 250  RGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETPP----TTQ 305
                 T    P  G S T          + Q    AL   S   S+  TE+PP    TT 
Sbjct: 4507 GTLGTTHITEPSTGTSHTPA----ATTGTTQHSTPALS--SPHPSSRTTESPPSPGTTTP 4560

Query: 306  PSFTFTLPAAATASPP---TSLLAPSTNPLLESLKKMQTPPSLPPC-------------- 348
               T T    ATA+P    TS L PS+ P    +  + T    P C              
Sbjct: 4561 GHTTATSRTTATATPSKTRTSTLLPSS-PTSAPITTVVTTGCEPQCAWSEWLDYSYPMPG 4619

Query: 349  PESAGAATTEALSPPKTPSLLPPLGL-----SQSGPP----GLLPSPSFDSK-------- 391
            P      T   +          PLGL     +Q G P    G +   S D          
Sbjct: 4620 PSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLGELGQVVECSLDFGLVCRNREQ 4679

Query: 392  ----------------------PPTTLLGLIPAPSMVPATD-------TKAPPTLQAETA 422
                                  P T        PS  P T        T A  T    + 
Sbjct: 4680 VGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTTASTGST 4739

Query: 423  TKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPPG 482
              P +T   +P PK      T  T+ SS A  ++S  +    P+ T+           P 
Sbjct: 4740 ATPSSTPGTAPPPKVLTSPATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSVTPI 4799

Query: 483  PSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTAPL 542
            PS  +T  ++ +LP  T+T   T   +  S  P  +        K TTT AT+ T+T   
Sbjct: 4800 PS--STLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSS 4857

Query: 543  FTG----LASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVST------------- 585
              G    L   T+A     +  P+   +S P   + +  +++++ +T             
Sbjct: 4858 TPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPSSTP 4917

Query: 586  ------------------TTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPT 627
                              T STATA+S     G P  S  + TP + S      P + P 
Sbjct: 4918 GTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTS--SKATPSSSPG 4975

Query: 628  TTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPF 687
            T T     +S  T  PTATS +A   S  G+T    +  T+  PT T S T+TP+ + P 
Sbjct: 4976 TATALPALRSTAT-TPTATSFTAIPSSSLGTTWTRLSQTTT--PTATMS-TATPS-STPE 5030

Query: 688  GSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSS-FTFGNSAAPAPA-TAPT 745
                 + L +           A     PG A     P+  ++ FT   S++P  A T PT
Sbjct: 5031 TVHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPT 5090

Query: 746  PAPASTIKIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFGA 805
              P ST+  +          T    T +A   +AT S    P+S+     G+T + +   
Sbjct: 5091 TTPMSTMSTIHTSSTPETTHTSTVLTTTATMTRATNST-ATPSSTL----GTTRILTELT 5145

Query: 806  ATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATTGAF 865
             T++   AT  TA+  S+       T  P T      P GS +     +T G++ T    
Sbjct: 5146 TTATTTAATGSTATLSSTPGTTWILT-EPSTIATVMVPTGSTATA--SSTLGTAHTPKVV 5202

Query: 866  SFGAGQSGSTATSTPFTGGLGQNALGTTGQSTPFAFNVGSTTES 909
            +  A    +TA++ P +  +G         S+   F+V + + S
Sbjct: 5203 TTMATMPTATASTVPSSSTVGTTRTPAVLPSSLPTFSVSTVSSS 5246



 Score =  103 bits (258), Expect = 6e-22
 Identities = 224/973 (23%), Positives = 336/973 (34%), Gaps = 167/973 (17%)

Query: 127  SSMSSLTGAYTSGIPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRSQTPERP 186
            S+ ++ T    + IPSSS     +  S T   +       PSS+P ++  S+   T    
Sbjct: 4312 STATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATT 4371

Query: 187  AKKIREEELCHHSSSSTPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQRKR----- 241
             +           S +TP +    +   K   TT      +    TP SS    R     
Sbjct: 4372 TRAT--------GSVATPSSTPGTAHTTKVPTTT-----TTGFTVTPSSSPGTARTPPVW 4418

Query: 242  -KVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTET 300
                  P+  G  +T    P   ++ T     L    +           S   ++  T T
Sbjct: 4419 ISTTTTPTTSGSTVTPSSVPGTTHTPTV----LTTTTTTVATGSMATPSSSTQTSGTTHT 4474

Query: 301  PPTTQPSFTFTLPAAATASPPTSLLAPSTNPLLESLKKMQ-TPPSLPPCPESAGAATTEA 359
            PP    + T T   + + S P ++    T+    +L     T PS       A    T  
Sbjct: 4475 PPVPNTTAT-THGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQ 4533

Query: 360  LSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPA----PSMVPATDTKAPP 415
             S P   S  P    ++S P     +P   +    T     P+     +++P++ T AP 
Sbjct: 4534 HSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPI 4593

Query: 416  TLQAETATKPQAT-------SAPSPAPKQSFL-----------------FGTQNTSPSSP 451
            T    T  +PQ         S P P P                       G +  + + P
Sbjct: 4594 TTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQP 4653

Query: 452  AAPAASSASPM------------------FKPIFTAPPK--SEKEGPTPPGPSVTATAPS 491
              P       +                  FK  F    +      G  P  P+ ++TA  
Sbjct: 4654 GVPLGELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMP 4713

Query: 492  SSS---------LPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPT----- 537
            SS+         L TT +TTA T      S   P+S P  AP  K  T+PAT PT     
Sbjct: 4714 SSTPGTTWILTELTTTATTTAST-----GSTATPSSTPGTAPPPKVLTSPATTPTATSSK 4768

Query: 538  ----------TTAPLFTGLA--SATSAVAPITSASPST-----DSASKPAFGFGINSVSS 580
                      TT P+ T  A  S  ++V PI S++  T     +  + P         SS
Sbjct: 4769 ATSSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGTLPEQTTTPVATMSTIHPSS 4828

Query: 581  SSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIF----------QFGKPPALPTTTT 630
            +  +T TST               S  S TP    I               P A P++T 
Sbjct: 4829 TPETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTP 4888

Query: 631  VTTF--SQSLPTAVPTA-TSSSAADFSGFGSTLATSAPATSSQPTLTFSNTST------- 680
             TT+  ++   TA  TA T S+A   S  G+T   + P+T++  T+   +T+T       
Sbjct: 4889 GTTWILTELTTTATTTASTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQAT 4948

Query: 681  -------PTFNIPFGSSAKSPLPSYPG-ANPQPAFGAAEGQPPGAAKPAL-TPSFGSSFT 731
                    T   P  +S+K+   S PG A   PA  +    P   +  A+ + S G+++T
Sbjct: 4949 AGTPHVSTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWT 5008

Query: 732  FGNSAAPAPATAPTPAPASTIKIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQ 791
              +      AT  T  P+ST    P  V T    T    T  A G  AT S+    A + 
Sbjct: 5009 RLSQTTTPTATMSTATPSST----PETVHTSTVLTATATTTGATGSVATPSSTPGTAHTT 5064

Query: 792  PAFGGSTAVFSFGAATSSGFGATTQTASSGSS-SSVFGSTTPSPFTFGGSAAPAGSGSFG 850
                 +T  F+   ++S G   T  T +  S+ S++  S+TP             + +  
Sbjct: 5065 KVPTTTTTGFTATPSSSPGTALTPPTTTPMSTMSTIHTSSTPETTHTSTVLTTTATMTRA 5124

Query: 851  IN-VATPGSS---------ATTGAFSFGAGQSGSTATSTPFTGGLGQNALGTTGQSTPFA 900
             N  ATP S+          TT A +  A  S +T +STP T  +    L          
Sbjct: 5125 TNSTATPSSTLGTTRILTELTTTATTTAATGSTATLSSTPGTTWI----LTEPSTIATVM 5180

Query: 901  FNVGSTTESKPVFGGTATP---TFGQNTPAPGVGTSGSSLSFGASSAPAQGFVGVGPFGS 957
               GST  +    G   TP   T     P     T  SS + G +  PA          S
Sbjct: 5181 VPTGSTATASSTLGTAHTPKVVTTMATMPTATASTVPSSSTVGTTRTPA-------VLPS 5233

Query: 958  AAPSFSIGAGSKT 970
            + P+FS+   S +
Sbjct: 5234 SLPTFSVSTVSSS 5246



 Score =  103 bits (256), Expect = 1e-21
 Identities = 212/921 (23%), Positives = 320/921 (34%), Gaps = 182/921 (19%)

Query: 133  TGAYTSGIPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSS-PASSRSQTPERPAKKIR 191
            T A T  + SS     +S  ++T   +       P+++ F++ P+SS   T  R ++   
Sbjct: 4283 TTATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTT 4342

Query: 192  EEELCHHSS-SSTPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRR 250
                   ++ SSTP  A   +     A TT      +   STPG++   K          
Sbjct: 4343 PTATMSTATPSSTPETAHTSTVLTTTATTTRATGSVATPSSTPGTAHTTK---------- 4392

Query: 251  GEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETP-----PTTQ 305
                 +P     G+++T        +    W +      +  ++ + +  P     PT  
Sbjct: 4393 -----VPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVL 4447

Query: 306  PSFTFTLPAAATASPPTSLLAPSTN---PLLESLKKMQTPPSLPPCPESAGAATTEALS- 361
             + T T+   + A+P +S     T    P+  +          P  P +   A T A S 
Sbjct: 4448 TTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSG 4507

Query: 362  --------PPKTPSLLPPL---GLSQSGPPGLL---PSPSFDSKPP---TTLLGLIPAPS 404
                     P T +   P    G +Q   P L    PS      PP   TT  G   A S
Sbjct: 4508 TLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATS 4567

Query: 405  ---------------MVPATDTKAPPTLQAETATKPQAT-------SAPSPAPKQSFL-- 440
                           ++P++ T AP T    T  +PQ         S P P P       
Sbjct: 4568 RTTATATPSKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDT 4627

Query: 441  ---------------FGTQNTSPSSPAAPAASSASPM------------------FKPIF 467
                            G +  + + P  P       +                  FK  F
Sbjct: 4628 YSNIRAAGGAVCEQPLGLECRAQAQPGVPLGELGQVVECSLDFGLVCRNREQVGKFKMCF 4687

Query: 468  TAPPKSE--KEGPTPPGPSVTATAPSSSS---------LPTTTSTTAPTFQPVFSSMGPP 516
                +      G  P  P+ ++TA  SS+         L TT +TTA T      S   P
Sbjct: 4688 NYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTTAST-----GSTATP 4742

Query: 517  ASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGIN 576
            +S P  AP  K  T+PAT PT T+      + ATS+ +P T+                  
Sbjct: 4743 SSTPGTAPPPKVLTSPATTPTATS------SKATSSSSPRTA------------------ 4778

Query: 577  SVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALP--TTTTVTTF 634
                +++   TSTAT           +++A S TP   S    G    LP  TTT V T 
Sbjct: 4779 ----TTLPVLTSTAT-----------KSTATSVTPIPSSTL--GTTGTLPEQTTTPVATM 4821

Query: 635  SQSLPTAVPTATSSSAADFSGFGSTLATSAPAT-SSQPTLTFSNTSTPTFNIPFGSSAKS 693
            S   P++ P  T +S    +   +T ATS+ +T SS P  T+  T   T      ++  +
Sbjct: 4822 STIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGPT 4881

Query: 694  PLPSY-PGAN----PQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAP 748
              PS  PG                     A P+ TP  G+++     +  A  T PT + 
Sbjct: 4882 ATPSSTPGTTWILTELTTTATTTASTGSTATPSSTP--GTTWILTEPSTTATVTVPTGST 4939

Query: 749  ASTIKIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAV---FSFGA 805
            A T     A   TP   T    T +    KAT S+    A++ PA   +       SF A
Sbjct: 4940 A-TASSTQATAGTPHVSTTA-TTPTVTSSKATPSSSPGTATALPALRSTATTPTATSFTA 4997

Query: 806  ATSSGFGAT----------TQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVAT 855
              SS  G T          T T S+ + SS   +   S      +     +GS     +T
Sbjct: 4998 IPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTATATTTGATGSVATPSST 5057

Query: 856  PGSSATTGAFSFGAGQSGSTATSTPFTGGLGQNALGTTGQSTPFAFNVGSTTESKPVFGG 915
            PG++ TT   +       +T +S+P T          +  ST    +   TT +  V   
Sbjct: 5058 PGTAHTTKVPTTTTTGFTATPSSSPGTALTPPTTTPMSTMSTIHTSSTPETTHTSTVLTT 5117

Query: 916  TATPTFGQNTPAPGVGTSGSS 936
            TAT T   N+ A    T G++
Sbjct: 5118 TATMTRATNSTATPSSTLGTT 5138



 Score =  102 bits (253), Expect = 2e-21
 Identities = 155/619 (25%), Positives = 237/619 (38%), Gaps = 108/619 (17%)

Query: 294  SNSVTETPPTTQPSFTFTLPAAATASPPT----SLLAPSTNPLLESLKKMQTPPSLPPCP 349
            + S T TP +T P  T+ L    TA+  T    S   PS+ P      K+ T  +  P  
Sbjct: 3559 ATSSTATPSST-PGTTWILTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATTPTA 3617

Query: 350  ESAGAATTEALSPPKTPSLLPPLG--LSQSGPPGLLPSPSF----------DSKPPTTLL 397
             S+ A ++   S P+T + LP L    ++S      P PSF           +  P   +
Sbjct: 3618 TSSKATSS---SSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPEQTTTPMATM 3674

Query: 398  GLIPAPSMVPATDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAAS 457
              I   S    T T    T +A T     + S PS  P  +++  T+ T+ ++  A    
Sbjct: 3675 STIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWIL-TELTTAATTTAATGP 3733

Query: 458  SASPMFKPIFT---APPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMG 514
            +A+P   P  T     P +      P G + TA++  +++      T+  T   V SS  
Sbjct: 3734 TATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTPTVISSRA 3793

Query: 515  PPASVPLPA---PFFKQTTTPATAPTTTA-------PLFTGLASATSAVAPITSASPSTD 564
             P+S P  A   P  + T T  TA + TA         +T L+  T+  A +++A+PS+ 
Sbjct: 3794 TPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPSST 3853

Query: 565  SASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPA 624
                        +V +S+V TTT+T T A+                   GS+       A
Sbjct: 3854 P----------ETVHTSTVLTTTTTTTRAT-------------------GSV-------A 3877

Query: 625  LPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFN 684
             P++T  T  +    T VPT T+      +GF +T  +S+P T+  P +  S T+TPT  
Sbjct: 3878 TPSSTPGTAHT----TKVPTTTT------TGFTAT-PSSSPGTALTPPVWISTTTTPTTR 3926

Query: 685  IPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAP 744
                 S  +P  S PG                      T + GS  T  +S   +  T  
Sbjct: 3927 ----GSTVTP-SSIPGTTHTATV---------LTTTTTTVATGSMATPSSSTQTSGTTHT 3972

Query: 745  TPAPASTIKIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFG 804
             P P +T       +P     T   A  S     AT+   G    ++P    ST      
Sbjct: 3973 PPVPNTTATTHGRSLPPSSPHTVRTAWTS-----ATSGILGTTHITEP----STVTSHTP 4023

Query: 805  AATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATTGA 864
            AAT+S    +T   SS   SS    + PSP    G+  P  +       AT   S T  +
Sbjct: 4024 AATTSTTQHSTPALSSPHPSSRTTESPPSP----GTTTPGHTRGTSRTTATATPSKTRTS 4079

Query: 865  FSFGAGQSGSTATSTPFTG 883
                +  + +  T+   TG
Sbjct: 4080 TLLPSSPTSAPITTVVTTG 4098



 Score = 94.7 bits (234), Expect = 4e-19
 Identities = 152/659 (23%), Positives = 244/659 (37%), Gaps = 85/659 (12%)

Query: 316  ATASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATT------EALSPPKTPSLL 369
            AT  PPT+ L  +T    ++L     P S P    +  A+TT      E L+ P+  S  
Sbjct: 2300 ATTPPPTTELETATTTTTQALFSTPQPTSSPGLTRAPPASTTAVPTLSEGLTSPRYTS-- 2357

Query: 370  PPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATD-------TKAPPTLQAET- 421
              LG + +G P   P+ S +   P      +P  S +P T           PPTL   T 
Sbjct: 2358 -TLGTATTGGP-TTPAGSTEPTVPGVATSTLPTRSALPGTTGSLGTWRPSQPPTLAPTTM 2415

Query: 422  -ATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFT-APPKSEKEGPT 479
              ++ + T   S A K+        T  S  +   A +++P  +   +     +  +G T
Sbjct: 2416 ATSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTETTMSPLTNTTTSQGTT 2475

Query: 480  PPGPSVTATAPSSSSLPTT--TSTTAPTFQPVFSSMG----PPASVPLPAPFFKQTTTPA 533
               P    T       PT+        TF+ + ++ G     P S+   A  + + +   
Sbjct: 2476 RCQPKCEWTEWFDVDFPTSGVAGGDMETFENIRAAGGKMCWAPKSIECRAENYPEVSIDQ 2535

Query: 534  TAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSS------SVSTTT 587
                 T  L TGL          T  +          F + +  +         S   T+
Sbjct: 2536 VGQVLTCSLETGL----------TCKNEDQTGRFNMCFNYNVRVLCCDDYSHCPSTPATS 2585

Query: 588  STATAASQP---FLFGAPQASAAS-----FTPAMGSIFQFGKPPALPTTTTVT---TFSQ 636
            STAT +S P   ++   P  +A +      T    S  +   PP + TTT  T   T S+
Sbjct: 2586 STATPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTTTATTPTVTSSK 2645

Query: 637  SLPTAVP-TATSSSAADFSGFGSTLATSAPATSSQPTLTF---SNTSTPTFNIPFGSSAK 692
            + P++ P TAT+  A   +    T  +  P  SS    T+   S T+TPT  +   + + 
Sbjct: 2646 ATPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATPSS 2705

Query: 693  SPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFG------SSFTFGNSAAP--APATAP 744
            +P  ++  +    A     G     A P+ TP         ++ T G +A P  +P TA 
Sbjct: 2706 TPETAHT-STVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTAL 2764

Query: 745  TPAPASTIKIVPAHVPTPIQP-TFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSF 803
            TP    +    P    + + P +  G TH+A  L  T +     + + P+    T+    
Sbjct: 2765 TPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTS---- 2820

Query: 804  GAATSSGFGATTQTASSGSSSSVFGSTTP--SPFTFGGSAAPAGSGSFGINVATPGSSAT 861
                    G T       + ++  G + P  SP T   +   A SG  G    T  S+ T
Sbjct: 2821 --------GTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVT 2872

Query: 862  TGAFSFGAGQSGSTATSTPFTGGLGQNALGTTGQSTPFAFNVGSTTESKPVFGGTATPT 920
            +      A  +G+T  STP       ++  T    +P     G TT +      TATP+
Sbjct: 2873 SHTL---AATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRT-TATATPS 2927



 Score = 94.4 bits (233), Expect = 5e-19
 Identities = 196/883 (22%), Positives = 310/883 (35%), Gaps = 142/883 (16%)

Query: 127  SSMSSLTGAYTSGIPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRSQTPERP 186
            S+ ++ T    + IPSSS     +  S T   +       PSS+P +   S+   T    
Sbjct: 3165 STATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATT 3224

Query: 187  AKKIREEELCHHSSSSTPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQRKRKVQL- 245
                         S +TP +    +   K   TT      +   +TP SS    R + + 
Sbjct: 3225 TGAT--------GSVATPSSTPGTAHTTKVLTTT-----TTGFTATPSSSPGTARTLPVW 3271

Query: 246  -----LPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTET 300
                  P+ RG  +T    P   ++ T         A+           S   ++  T T
Sbjct: 3272 ISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVAT----GSMATPSSSTQTSGTTHT 3327

Query: 301  PPTTQPSFTFTLPAAATASPPTSLLAPSTNPLLESLKKMQ-TPPSLPPCPESAGAATTEA 359
            PP    + T T   + + S P ++    T+    +L     T PS       A    T  
Sbjct: 3328 PPVPNTTAT-THGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQ 3386

Query: 360  LSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPS----MVPATDTKAPP 415
             S P   S  P    ++S P     +P        T     P+ +    ++P++ T AP 
Sbjct: 3387 HSTPALSSPHPSSRTTESPPSPGTTTPGHTRATSRTTATATPSKTRTSTLLPSSPTSAPI 3446

Query: 416  TLQAETATKPQAT-------SAPSPAPKQSFL-----------------FGTQNTSPSSP 451
            T       +PQ         S P P P                       G +  + + P
Sbjct: 3447 TTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQP 3506

Query: 452  AAPAASSASPM------------------FKPIFTAPPKSE--KEGPTPPGPSVTATAPS 491
              P       +                  FK  F    +      G  P  P+ ++TA  
Sbjct: 3507 GVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTATP 3566

Query: 492  SSSLPTT----TSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLA 547
            SS+  TT      TTA T      S   P+S P  AP  K  T+ AT PT T+   T  +
Sbjct: 3567 SSTPGTTWILTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATTPTATSSKATSSS 3626

Query: 548  SA-TSAVAPI--TSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAAS-------QPF 597
            S  T+   P+  ++A+ ST ++  P   F + +  +    TTT  AT ++       +  
Sbjct: 3627 SPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPEQTTTPMATMSTIHPSSTPETT 3686

Query: 598  LFGAPQASAASFTPAMGSIFQFGKPPALP-----TTTTVTTFSQSLPTAVPTATSSSAAD 652
                   + A+ T A  S+      P         TT  TT + + PTA P++T  +   
Sbjct: 3687 HTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWI 3746

Query: 653  FSGFGSTLATSAP------ATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPG-ANPQP 705
             +   +T   + P      A+S++ T       T T   P   S+++   S PG A   P
Sbjct: 3747 LTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTPTVISSRATPSSSPGTATALP 3806

Query: 706  AFGAAEGQPPGAAKPAL-TPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVPAHVPTPIQ 764
            A  +    P   +  A+ + S G+++T  +      AT  T  P+ST + V  H  T + 
Sbjct: 3807 ALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPSSTPETV--HTSTVL- 3863

Query: 765  PTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAATSSGFGATTQTA-SSGSS 823
                  T +    +AT S   A  SS P    +T V      T++GF AT  ++  +  +
Sbjct: 3864 ------TTTTTTTRATGSV--ATPSSTPGTAHTTKV---PTTTTTGFTATPSSSPGTALT 3912

Query: 824  SSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATTGAFSFGAGQSGSTATSTPFTG 883
              V+ STT +P T G +  P+                            G+T T+T  T 
Sbjct: 3913 PPVWISTTTTPTTRGSTVTPSSI-------------------------PGTTHTATVLT- 3946

Query: 884  GLGQNALGTTGQSTPFAFNVGSTTESKPVFGGTATPTFGQNTP 926
                  + T   +TP +    S T   P    T   T G++ P
Sbjct: 3947 -TTTTTVATGSMATPSSSTQTSGTTHTPPVPNTTATTHGRSLP 3988



 Score = 93.2 bits (230), Expect = 1e-18
 Identities = 181/817 (22%), Positives = 291/817 (35%), Gaps = 114/817 (13%)

Query: 127  SSMSSLTGAYTSGIPSSSRNAITSSYSSTRGISQLWKRNGPSSSP---FSSPASSRSQTP 183
            S+ ++ T    + IPSSS     +  S T   +       PSS+P    +S   + + T 
Sbjct: 3810 STATTPTATSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTTTT 3869

Query: 184  ERPAKKIREEELCHHSSSSTPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQRKRKV 243
             R    +        + SSTP  A           TT      +   S+PG++      +
Sbjct: 3870 TRATGSVA-------TPSSTPGTAHTTK-----VPTTTTTGFTATPSSSPGTALTPPVWI 3917

Query: 244  QLL--PSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETP 301
                 P+ RG  +T    P   ++ T         A+           S   ++  T TP
Sbjct: 3918 STTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVAT----GSMATPSSSTQTSGTTHTP 3973

Query: 302  PTTQPSFTFTLPAAATASPPTSLLA--PSTNPLLESLKKMQTPPSLPPCPESAGAATTEA 359
            P    + T    +   +SP T   A   +T+ +L +     T PS       A   +T  
Sbjct: 3974 PVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHI--TEPSTVTSHTPAATTSTTQ 4031

Query: 360  LSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPS----MVPATDTKAPP 415
             S P   S  P    ++S P     +P        T     P+ +    ++P++ T AP 
Sbjct: 4032 HSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPSKTRTSTLLPSSPTSAPI 4091

Query: 416  TLQAETATKPQAT-------SAPSPAPKQSFL-----------------FGTQNTSPSSP 451
            T    T  +PQ         S P P P                       G +  + + P
Sbjct: 4092 TTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQP 4151

Query: 452  AAPAASSASPM------------------FKPIFTAPPK----SEKEGPTPPGPSVTAT- 488
              P       +                  FK  F    +    +    P+ P  S TAT 
Sbjct: 4152 GVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTATP 4211

Query: 489  --APSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGL 546
               P ++ + T  +TTA T +    S   P+S P        TT   T P+TTA +   +
Sbjct: 4212 SSTPGTTWILTKLTTTATTTEST-GSTATPSSTP-------GTTWILTEPSTTATVT--V 4261

Query: 547  ASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFG-APQAS 605
             + ++A A  T A+  T   S  A      +V+SS  +  +S  TA + P L   A   +
Sbjct: 4262 PTGSTATASSTQATAGTPHVSTTAT---TPTVTSSKATPFSSPGTATALPALRSTATTPT 4318

Query: 606  AASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATSAP 665
            A SFT             A+P+++  TT+++   T  PTAT S+A   S   +   ++  
Sbjct: 4319 ATSFT-------------AIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVL 4365

Query: 666  ATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPS 725
             T++  T    + +TP+       + K P  +  G    P+      + P       T  
Sbjct: 4366 TTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTP 4425

Query: 726  FGSSFTFGNSAAPAPATAPTPAPASTIKIVPAHVPTPIQPT-FGGATHSAFGLKATASAF 784
              S  T   S+ P     PT    +T  +    + TP   T   G TH+      TA+  
Sbjct: 4426 TTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTTATTH 4485

Query: 785  GAPASSQPAFGGSTAVFSFGAATSSGFGATTQT-ASSGSSSSVFGSTTPSPFTFGGSAAP 843
            G   S        TA   + +ATS   G T  T  S+G+S +   +T  +  +    ++P
Sbjct: 4486 GRSLSPSSPHTVRTA---WTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSP 4542

Query: 844  AGSGSFGINVATPGSSATTGAFSFGAGQSGSTATSTP 880
              S     +  +PG++            S +TAT+TP
Sbjct: 4543 HPSSRTTESPPSPGTTTP----GHTTATSRTTATATP 4575



 Score = 92.4 bits (228), Expect = 2e-18
 Identities = 212/914 (23%), Positives = 322/914 (35%), Gaps = 168/914 (18%)

Query: 173  SSPASSRSQTPERPAKKIREEELCHHSSSSTPLAADKESQGEKAADTTPRKKQNSNSQST 232
            S+PA+S + TP                 SSTP      ++   AA TT      +   ST
Sbjct: 3556 STPATSSTATP-----------------SSTPGTTWILTEQTTAATTTATTGSTAIPSST 3598

Query: 233  PGSSGQRK--RKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWF-------- 282
            PG++   K        P+    + T    P+   ++        K  +  +         
Sbjct: 3599 PGTAPPPKVLTSTATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLG 3658

Query: 283  ------NQALEDKSDAASNSVTETPPTTQPSFTFTLPAA---ATASPPTSLLAPSTNPLL 333
                   Q     +  ++   + TP TT  S   T  A    AT+S  T    P T  +L
Sbjct: 3659 TTGTLPEQTTTPMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWIL 3718

Query: 334  ESLKKMQTPPSL--PPCPESAGAATTEALSPPKTPSLLP-PLGL-----SQSGPPGLLPS 385
              L    T  +   P    S+   TT  L+ P T + +  P G      S     G L  
Sbjct: 3719 TELTTAATTTAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKV 3778

Query: 386  PSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAETATKPQATSA---PSPAPKQSFLFG 442
             +  +  PT +      PS  P T T A P L++ TAT P ATS    PS +   ++   
Sbjct: 3779 LTSTATTPTVISSRA-TPSSSPGTAT-ALPALRS-TATTPTATSVTAIPSSSLGTAWTRL 3835

Query: 443  TQNTSPSSPAAPAASSASPMF---KPIFTAPPKSEKEGPTPPGPSVTATAPSSSSLPTTT 499
            +Q T+P++  + A  S++P       + T    + +   +   PS T     ++ +PTTT
Sbjct: 3836 SQTTTPTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTT 3895

Query: 500  STTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTAP--------LFTGLASATS 551
             TT  T  P  S    P +   P  +   TTTP T  +T  P          T L + T+
Sbjct: 3896 -TTGFTATPSSS----PGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTT 3950

Query: 552  AVAPITSASPSTDSASK-------------PAFGFGINSVSSSSVSTTTSTATAA----- 593
             VA  + A+PS+ + +                 G  +   S  +V T  ++AT+      
Sbjct: 3951 TVATGSMATPSSSTQTSGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTT 4010

Query: 594  --SQPFLF-----GAPQASAASFTPAMGSIFQFGK----PPALPTTTTVTT--FSQSLPT 640
              ++P         A  ++    TPA+ S     +    PP+  TTT   T   S++  T
Sbjct: 4011 HITEPSTVTSHTPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTAT 4070

Query: 641  AVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPG 700
            A P+ T +S    S   S   T+   T  +P   +S      ++ P    +     +Y  
Sbjct: 4071 ATPSKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWL--DYSYPMPGPSGGDFDTY-- 4126

Query: 701  ANPQPAFGAAEGQP----------PGAAKPALTPSFGSSFTFG----------------- 733
            +N + A GA   QP          PG     L      S  FG                 
Sbjct: 4127 SNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFN 4186

Query: 734  ----------NSAAPAPATAPTPAPASTIKIVPAHVPTPIQPTFGGATHSAFGLKATASA 783
                            PAT+ T  P+ST    P       + T    T  + G  AT   
Sbjct: 4187 YEIRVFCCNYGHCPSTPATSSTATPSST----PGTTWILTKLTTTATTTESTGSTAT--- 4239

Query: 784  FGAPASSQPAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSVFG-----STTPSPFTFG 838
                 SS P   G+T + +  + T++    T  TA++ S+ +  G     +T  +P    
Sbjct: 4240 ----PSSTP---GTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTS 4292

Query: 839  GSAAPAGSGSFGINVATPGSSATT-GAFSFGAGQSGSTATSTPFTGGLGQNALGTTGQST 897
              A P  S      +    S+ATT  A SF A  S S  T+      L Q    T   ST
Sbjct: 4293 SKATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWT---RLSQTTTPTATMST 4349

Query: 898  PFAFNVGSTTESKPVFGGTATPTFGQNTPAPGVGTSGSSLSFGASSAPAQGFVGVGPFGS 957
                +   T  +  V   TAT T    + A    T G++ +    +    GF       +
Sbjct: 4350 ATPSSTPETAHTSTVLTTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGF-------T 4402

Query: 958  AAPSFSIGAGSKTP 971
              PS S G     P
Sbjct: 4403 VTPSSSPGTARTPP 4416



 Score = 90.5 bits (223), Expect = 7e-18
 Identities = 161/668 (24%), Positives = 241/668 (36%), Gaps = 110/668 (16%)

Query: 316  ATASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALSPPKTPSLLPPLGLS 375
            AT+S  T    P T  +L  L              +  A TTE+     TPS  P     
Sbjct: 4204 ATSSTATPSSTPGTTWILTKL--------------TTTATTTESTGSTATPSSTP----- 4244

Query: 376  QSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPP-------TLQAETATKPQAT 428
              G   +L  PS      TT    +P  S   A+ T+A         T    T T  +AT
Sbjct: 4245 --GTTWILTEPS------TTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKAT 4296

Query: 429  SAPSPAPKQSF----LFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPPGPS 484
               SP    +        T  T+ S  A P++S  +   +   T  P +     TP   S
Sbjct: 4297 PFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPS--S 4354

Query: 485  VTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFT 544
               TA +S+ L TT +TT  T      S+  P+S P  A   K  TT  T  T T     
Sbjct: 4355 TPETAHTSTVLTTTATTTRAT-----GSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSP 4409

Query: 545  GLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQA 604
            G A         T+   ++ S   P+   G     +   +TTT+ AT +          A
Sbjct: 4410 GTARTPPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGS---------MA 4460

Query: 605  SAASFTPAMGSIFQFGKPPALPTTTTVT---TFSQSLPTAVPTATSSSAADFSGFGSTLA 661
            + +S T   G+       P +P TT  T   + S S P  V TA +S+ +   G  + + 
Sbjct: 4461 TPSSSTQTSGTT----HTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLG-TTHIT 4515

Query: 662  TSAPATSSQPTLTFSNT--STPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAK 719
              +  TS  P  T   T  STP  + P  SS  +  P  PG    P    A  +    A 
Sbjct: 4516 EPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTT-TPGHTTATSRTTATAT 4574

Query: 720  PALTPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVPAH----------VPTPIQPTFGG 769
            P+ T +        ++  P   ++PT AP +T+                   P+    GG
Sbjct: 4575 PSKTRT--------STLLP---SSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGG 4623

Query: 770  ATHSAFGLKATASA-----FGAPASSQPAFGGSTAVFSFGAATSSGFGATTQTASSGSSS 824
               +   ++A   A      G    +Q   G            S  FG   +        
Sbjct: 4624 DFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLGELGQVVECSLDFGLVCRNREQVGKF 4683

Query: 825  SVFGSTTPSPF--TFGGSAAPAGSGSFGINVATPGSS-----ATTGAFSFGAGQSGSTAT 877
             +  +     F   +G   +   + S  +  +TPG++      TT A +     +GSTAT
Sbjct: 4684 KMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATT--TASTGSTAT 4741

Query: 878  STPFTGGLGQNALGTTGQSTPFAFNVGSTTESK-------PVFGGTATPTFGQN-TPAPG 929
             +   G      + T+  +TP A +  +T+ S        PV   TAT +   + TP P 
Sbjct: 4742 PSSTPGTAPPPKVLTSPATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSVTPIPS 4801

Query: 930  --VGTSGS 935
              +GT+G+
Sbjct: 4802 STLGTTGT 4809



 Score = 90.1 bits (222), Expect = 9e-18
 Identities = 189/843 (22%), Positives = 304/843 (36%), Gaps = 89/843 (10%)

Query: 167  PSSSPFSSPASSRSQTPERPAKKIREEELCHHSSSSTPLAADKESQGEKAADTTPRKKQN 226
            P++S  ++P+S+   T                 S++TP +  + +   K   TT      
Sbjct: 2582 PATSSTATPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTTTATTPTV 2641

Query: 227  SNSQSTPGSSGQRKRKVQLLPSR----RGEQLTLPPPPQLGYSITAEDLDLEKKASLQWF 282
            ++S++TP SS      +  L S         +T  P   LG + T         A++   
Sbjct: 2642 TSSKATPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTA 2701

Query: 283  NQALEDKSDAASNSVTETPPTTQPSFTFTLPA-----AATASPPTSLLAPSTNPLLESLK 337
              +   ++   S  +T T  TT  + +   P+     A T   PT+     T     S  
Sbjct: 2702 TPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPG 2761

Query: 338  KMQTPP---SLPPCPESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPT 394
               TPP   S    P + G+  T +  P  T +       + +   G + +PS  ++   
Sbjct: 2762 TALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSG 2821

Query: 395  TLLGLIPAPSMVPATDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNTSPS---SP 451
            T     P P+ +  T  ++ P     T  +   TSA S       L  T  T PS   S 
Sbjct: 2822 T-THTPPVPNTMATTHGRSLPPSSPHT-VRTAWTSATS-----GILGTTHITEPSTVTSH 2874

Query: 452  AAPAASSASPMFKPIFTAPPKSEKEGPTPPGPS------------VTATAPSSSSLPTTT 499
               A +  +    P  ++P  S +   +PP P              TATA  S +  +T 
Sbjct: 2875 TLAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTL 2934

Query: 500  STTAPTFQPVFS--SMGPPA----------SVPLPAPFFKQTTT-----PATAPTTTAPL 542
              ++PT  P+ +  +MG             S P+P P      T      A       PL
Sbjct: 2935 LPSSPTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPL 2994

Query: 543  FTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFL--FG 600
                 +      P+       +     +  FG+   +   V           + F   +G
Sbjct: 2995 GLECRAQAQPGVPLRELGQVVEC----SLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYG 3050

Query: 601  APQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSL-PTAVPTATSSSAADFSGFGST 659
               ++ A+ + AM S    G    L   TT  T ++S   TA P++T  +    +   +T
Sbjct: 3051 HCPSTPATSSTAMPSSTP-GTTWILTELTTTATTTESTGSTATPSSTPGTTWILTEPSTT 3109

Query: 660  LATSAP------ATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQ 713
               + P      A+S+Q T    + ST        SS  +P  S   A   PA  +    
Sbjct: 3110 ATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATT 3169

Query: 714  PPGAAKPAL-TPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVPAHVPTPIQPTFGGATH 772
            P   +  A+ + S G+++T  +      AT  T  P+ST + V          T  GAT 
Sbjct: 3170 PTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATTTGATG 3229

Query: 773  SAFGLKATASAFGAPASSQPAFGGSTAVFSFGAATSSGFGAT-TQTASSGSSSSVFGSTT 831
            S            A  SS P    +T V +    T++GF AT + +  +  +  V+ STT
Sbjct: 3230 SV-----------ATPSSTPGTAHTTKVLT---TTTTGFTATPSSSPGTARTLPVWISTT 3275

Query: 832  PSPFTFGGSAAPAGSGSFGINVATPGSSATTGAFSFGAGQSGSTATS-TPFTGGLGQNAL 890
             +P T G +  P+             ++ TT A    A  S ST TS T  T  +     
Sbjct: 3276 TTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTTA 3335

Query: 891  GTTGQ----STPFAFNVGSTTESKPVFGGT--ATPTFG-QNTPAPGVGTSGSSLSFGASS 943
             T G+    S+P       T+ +    G T    P+ G  +TPA   GT+  S    +S 
Sbjct: 3336 TTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSP 3395

Query: 944  APA 946
             P+
Sbjct: 3396 HPS 3398



 Score = 87.8 bits (216), Expect = 5e-17
 Identities = 186/757 (24%), Positives = 258/757 (34%), Gaps = 144/757 (19%)

Query: 290  SDAASNSVTETPPTTQPSFTFTLPAAATASPPTSLLAPSTNPLLESLKKMQTPP---SLP 346
            S A ++S   T  T   S T T P   T+S  T   +P T   L +L+   T P   S  
Sbjct: 4265 STATASSTQATAGTPHVSTTATTPTV-TSSKATPFSSPGTATALPALRSTATTPTATSFT 4323

Query: 347  PCPESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTT-LLGLIPAPSM 405
              P S+   T   LS   TP+         S P     S    +   TT   G +  PS 
Sbjct: 4324 AIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRATGSVATPSS 4383

Query: 406  VPATDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNTSP---SSPAAPAASSASPM 462
             P T      T +  T T    T  PS +P      GT  T P   S+   P  S     
Sbjct: 4384 TPGT----AHTTKVPTTTTTGFTVTPSSSP------GTARTPPVWISTTTTPTTS----- 4428

Query: 463  FKPIFTAPPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLP 522
                          G T    SV  T  + + L TTT+T A        SM  P+S    
Sbjct: 4429 --------------GSTVTPSSVPGTTHTPTVLTTTTTTVAT------GSMATPSS---- 4464

Query: 523  APFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSS 582
                  T T  T  T   P        T+A     S SPS+    + A+    +    ++
Sbjct: 4465 -----STQTSGTTHTPPVP-------NTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTT 4512

Query: 583  VSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTT--VTTFSQSLPT 640
              T  ST T+ +     G  Q S  + +    S      PP+  TTT    T  S++  T
Sbjct: 4513 HITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTAT 4572

Query: 641  AVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPG 700
            A P+ T +S    S   S   T+   T  +P   +S      ++ P    +     +Y  
Sbjct: 4573 ATPSKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWL--DYSYPMPGPSGGDFDTY-- 4628

Query: 701  ANPQPAFGAAEGQP----------PGAAKPALTPSFGSSFTFG----------------- 733
            +N + A GA   QP          PG     L      S  FG                 
Sbjct: 4629 SNIRAAGGAVCEQPLGLECRAQAQPGVPLGELGQVVECSLDFGLVCRNREQVGKFKMCFN 4688

Query: 734  ----------NSAAPAPATAPTPAPASTIKIVPAHVPTPIQPTFGGATHSAFGLKATASA 783
                            PAT+ T  P+ST    P       + T    T ++ G  AT S+
Sbjct: 4689 YEIRVFCCNYGHCPSTPATSSTAMPSST----PGTTWILTELTTTATTTASTGSTATPSS 4744

Query: 784  FGAPA---------SSQPAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSVFGSTTPSP 834
                A         ++ P    S A  S    T++     T TA+  +++SV    TP P
Sbjct: 4745 TPGTAPPPKVLTSPATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSV----TPIP 4800

Query: 835  FTFGG--------SAAPAGSGSFGINVATPGSS-----ATTGAFSFGAGQSGSTATSTPF 881
             +  G        +  P  + S     +TP ++      TT A +  A  S ST +STP 
Sbjct: 4801 SSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTPG 4860

Query: 882  TGGLGQNALGTTGQSTPFAFNVGSTTESKP-------VFGGTATPTFGQNTPAPGVGTSG 934
            T  +      TT  +T  A    +T  S P           TAT T    + A    T G
Sbjct: 4861 TTWILTEL--TTAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPSSTPG 4918

Query: 935  SSLSFGASSAPAQGFVGVGPFGSAAPSFSIGAGSKTP 971
            ++      S  A   V   P GS A + S  A + TP
Sbjct: 4919 TTWILTEPSTTATVTV---PTGSTATASSTQATAGTP 4952



 Score = 87.0 bits (214), Expect = 8e-17
 Identities = 177/734 (24%), Positives = 248/734 (33%), Gaps = 131/734 (17%)

Query: 290  SDAASNSVTETPPTTQPSFTFTLPAAATASPPTSLLAPSTNPLLESLKKMQTPP---SLP 346
            S A   S   T P  +   T       T+S  T   +P T   L +L+   T P   S+ 
Sbjct: 2615 STATPTSTLRTAPPPKVLTTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSVT 2674

Query: 347  PCPESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTT-LLGLIPAPSM 405
            P P S+   T   LS   TP+         S P     S    +   TT   G +  PS 
Sbjct: 2675 PIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSS 2734

Query: 406  VPATDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNTSP---SSPAAPAASSASPM 462
             P T      T +  T T    T+ PS +P      GT  T P   S+   P    +   
Sbjct: 2735 TPGT----AHTTKVPTTTTTGFTATPSSSP------GTALTPPVWISTTTTPTTRGS--- 2781

Query: 463  FKPIFTAPPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLP 522
                 T  P S       PG + TAT      + TTT+TT  T      SM  P+S    
Sbjct: 2782 -----TVTPSS------IPGTTHTAT------VLTTTTTTVAT-----GSMATPSS---- 2815

Query: 523  APFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSS 582
                  T T  T  T   P        T A     S  PS+    + A+    + +  ++
Sbjct: 2816 -----STQTSGTTHTPPVP-------NTMATTHGRSLPPSSPHTVRTAWTSATSGILGTT 2863

Query: 583  VSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTT--VTTFSQSLPT 640
              T  ST T+ +     G  Q S  + +    S      PP+  TTT    T  S++  T
Sbjct: 2864 HITEPSTVTSHTLAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTAT 2923

Query: 641  AVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPG 700
            A P+ T +S    S   S   T+      +P   +S      ++ P    +     +Y  
Sbjct: 2924 ATPSKTRTSTLLPSSPTSAPITTVVTMGCEPQCAWSEWL--DYSYPMPGPSGGDFDTY-- 2979

Query: 701  ANPQPAFGAAEGQP----------PGAAKPALTPSFGSSFTFG----------------- 733
            +N + A GA   QP          PG     L      S  FG                 
Sbjct: 2980 SNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFN 3039

Query: 734  ----------NSAAPAPATAPTPAPASTIKIVPAHVPTPIQPTFGGATHSAFGLKATASA 783
                            PAT+ T  P+ST    P       + T    T  + G  AT   
Sbjct: 3040 YEIRVFCCNYGHCPSTPATSSTAMPSST----PGTTWILTELTTTATTTESTGSTAT--- 3092

Query: 784  FGAPASSQPAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSVFG-----STTPSPFTFG 838
                 SS P   G+T + +  + T++    T  TA++ S+ +  G     +T  +P    
Sbjct: 3093 ----PSSTP---GTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTS 3145

Query: 839  GSAAPAGSGSFGINVATPGSSATT-GAFSFGAGQSGSTATSTPFTGGLGQNALGTTGQST 897
              A P  S      +    S+ATT  A SF A  S S  T+      L Q    T   ST
Sbjct: 3146 SKATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWT---RLSQTTTPTATMST 3202

Query: 898  PFAFNVGSTTESKPVFGGTATPTFGQNTPAPGVGTSGSSLSFGASSAPAQGFVGVGPFGS 957
                +   T  +  V   TAT T    + A    T G++ +    +    GF       +
Sbjct: 3203 ATPSSTPETVHTSTVLTTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGF-------T 3255

Query: 958  AAPSFSIGAGSKTP 971
            A PS S G     P
Sbjct: 3256 ATPSSSPGTARTLP 3269



 Score = 87.0 bits (214), Expect = 8e-17
 Identities = 177/752 (23%), Positives = 264/752 (35%), Gaps = 164/752 (21%)

Query: 313  PAAATASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALSPPKTPSLLPPL 372
            PA ++ + P+S   P T  +L  L              +  A TTE+     TPS  P  
Sbjct: 3056 PATSSTAMPSS--TPGTTWILTEL--------------TTTATTTESTGSTATPSSTP-- 3097

Query: 373  GLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPP-------TLQAETATKP 425
                 G   +L  PS      TT    +P  S   A+ T+A         T    T T  
Sbjct: 3098 -----GTTWILTEPS------TTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSS 3146

Query: 426  QATSAPSPAPKQSF----LFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPP 481
            +AT   SP    +        T  T+ S  A P++S  +   +   T  P +     TP 
Sbjct: 3147 KATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPS 3206

Query: 482  GPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTAP 541
              S   T  +S+ L TT +TT  T      S+  P+S P  A   K  TT  T  T T  
Sbjct: 3207 --STPETVHTSTVLTTTATTTGAT-----GSVATPSSTPGTAHTTKVLTTTTTGFTATPS 3259

Query: 542  LFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGA 601
               G A         T+   +  S   P+   G     +   +TTT+ AT +        
Sbjct: 3260 SSPGTARTLPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGS-------- 3311

Query: 602  PQASAASFTPAMGSIFQFGKPPALPTTTTVT---TFSQSLPTAVPTATSSSAADFSGFGS 658
              A+ +S T   G+       P +P TT  T   + S S P  V TA +S+ +   G  +
Sbjct: 3312 -MATPSSSTQTSGTT----HTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLG-TT 3365

Query: 659  TLATSAPATSSQPTLTFSNT--STPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPG 716
             +   +  TS  P  T   T  STP  + P  SS  +  P  PG    P    A  +   
Sbjct: 3366 HITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTT-TPGHTRATSRTTA 3424

Query: 717  AAKPALTPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVPAH--------------VPTP 762
             A P+ T +        ++  P   ++PT AP +T+  +                 +P P
Sbjct: 3425 TATPSKTRT--------STLLP---SSPTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGP 3473

Query: 763  ----------IQPTFGGATHSAFGLKATASA------------------FGAPASSQPAF 794
                      I+   G       GL+  A A                  FG    ++   
Sbjct: 3474 SGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQV 3533

Query: 795  GGSTAVFSFGAAT-SSGFG---ATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFG 850
            G     F++        +G   +T  T+S+ + SS  G+T         +   A +GS  
Sbjct: 3534 GKFKMCFNYEIRVFCCNYGHCPSTPATSSTATPSSTPGTTWILTEQTTAATTTATTGSTA 3593

Query: 851  INVATPG---------SSATTGAFSFGAGQSGST----------------ATSTPFTGGL 885
            I  +TPG         S+ATT   +     S S+                +T+T FT  +
Sbjct: 3594 IPSSTPGTAPPPKVLTSTATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSFT-PI 3652

Query: 886  GQNALGTTG-----QSTPFA-------FNVGSTTESKPVFGGTATPTFGQNTPAPGVGTS 933
                LGTTG      +TP A        +   TT +  V    AT T   ++ +    T 
Sbjct: 3653 PSFTLGTTGTLPEQTTTPMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTP 3712

Query: 934  GSSLSFGASSAPAQGFVGVGPFGSAAPSFSIG 965
            G++      +  A      GP  +A PS + G
Sbjct: 3713 GTTWILTELTTAATTTAATGP--TATPSSTPG 3742



 Score = 86.7 bits (213), Expect = 1e-16
 Identities = 202/901 (22%), Positives = 321/901 (35%), Gaps = 159/901 (17%)

Query: 121  NKRSRSSSMSSLTG--AYTSGIPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASS 178
            +K + SSS  + T   A  S   + +  ++T   SS+ G +  W R   +++P ++ +++
Sbjct: 2644 SKATPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTT--WTRLSQTTTPTATMSTA 2701

Query: 179  R-SQTPERPAKKIREEELCHHSSSSTPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSG 237
              S TPE              + +ST L A   + G   +  TP         STPG++ 
Sbjct: 2702 TPSSTPET-------------AHTSTVLTATATTTGATGSVATP--------SSTPGTAH 2740

Query: 238  QRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSV 297
              K     +P+      T  P    G ++T               +          +++ 
Sbjct: 2741 TTK-----VPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTA 2795

Query: 298  T--ETPPTTQPSFTFTLPAAATASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAA 355
            T   T  TT  + +   P+++T +  T+   P  N +  +  +   PPS P    +A  +
Sbjct: 2796 TVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTMATTHGR-SLPPSSPHTVRTAWTS 2854

Query: 356  TTEAL---------SPPKTPSLLPPLGLSQSGPPGLL---PSPSFDSKPP---TTLLGLI 400
             T  +         S   + +L    G +Q   P L    PS      PP   TT  G  
Sbjct: 2855 ATSGILGTTHITEPSTVTSHTLAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHT 2914

Query: 401  PAPS---------------MVPATDTKAPPTLQAETATKPQAT-------SAPSPAPKQS 438
             A S               ++P++ T AP T       +PQ         S P P P   
Sbjct: 2915 TATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSG- 2973

Query: 439  FLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPPGPSV-----TATAPSSS 493
               G  +T  +  AA  A    P+           E      PG  +             
Sbjct: 2974 ---GDFDTYSNIRAAGGAVCEQPL---------GLECRAQAQPGVPLRELGQVVECSLDF 3021

Query: 494  SLPTTTSTTAPTFQPVFS--------SMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTG 545
             L          F+  F+        + G   S P  +     T  P++ P TT  L   
Sbjct: 3022 GLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATS----STAMPSSTPGTTWILTEL 3077

Query: 546  LASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVST--TTSTATAASQPFLFGAPQ 603
              +AT+  +  ++A+PS    S P   + +   S+++  T  T STATA+S     G P 
Sbjct: 3078 TTTATTTESTGSTATPS----STPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPH 3133

Query: 604  ASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATS 663
             S  + TP + S      P + P T T      +LP    TAT+ +A  F        T+
Sbjct: 3134 VSTTATTPTVTS--SKATPFSSPGTAT------ALPALRSTATTPTATSF--------TA 3177

Query: 664  APATSSQPTLT-FSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKPAL 722
             P++S   T T  S T+TPT  +   + + +P   +  +          G     A P+ 
Sbjct: 3178 IPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHT-STVLTTTATTTGATGSVATPSS 3236

Query: 723  TPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVPAHVPTPIQPTFGGATHSAFGLKATAS 782
            TP    +     +        P+ +P  T + +P  + T   PT  G+T        T S
Sbjct: 3237 TPGTAHTTKVLTTTTTGFTATPSSSPG-TARTLPVWISTTTTPTTRGST-------VTPS 3288

Query: 783  AFGAPASSQPAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAA 842
            +      +      +T   + G+           T SS + +S    T P P T   +  
Sbjct: 3289 SIPGTTHTPTVLTTTTTTVATGSMA---------TPSSSTQTSGTTHTPPVPNTTATTHG 3339

Query: 843  PAGSGSFGINVATPGSSATTGAFSFGAGQSGSTATSTPFTGGLGQNA--LGTTGQSTP-- 898
             + S S    V T  +SAT+G         G+T  + P TG     A   GTT  STP  
Sbjct: 3340 RSLSPSSPHTVRTAWTSATSGTL-------GTTHITEPSTGTSHTPAATTGTTQHSTPAL 3392

Query: 899  FAFNVGSTTESKPVFGGTATPTFGQ------NTPAPGVGTSGSSLSFGASSAPAQGFVGV 952
             + +  S T   P   GT TP   +       T  P    + + L    +SAP    V +
Sbjct: 3393 SSPHPSSRTTESPPSPGTTTPGHTRATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTM 3452

Query: 953  G 953
            G
Sbjct: 3453 G 3453



 Score = 84.7 bits (208), Expect = 4e-16
 Identities = 178/760 (23%), Positives = 271/760 (35%), Gaps = 132/760 (17%)

Query: 290  SDAASNSVTETPPTTQPSFTFTLPAAATASPPTSLLAPSTNPLLESLKKMQTPP---SLP 346
            S A ++S   T  T   S T T P   T+S  T   +P T   L +L+   T P   S  
Sbjct: 3118 STATASSTQATAGTPHVSTTATTPTV-TSSKATPFSSPGTATALPALRSTATTPTATSFT 3176

Query: 347  PCPESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTT-LLGLIPAPSM 405
              P S+   T   LS   TP+         S P  +  S    +   TT   G +  PS 
Sbjct: 3177 AIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATTTGATGSVATPSS 3236

Query: 406  VPATDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKP 465
             P T      T +  T T    T+ PS +P      GT  T P       +++ +P  + 
Sbjct: 3237 TPGT----AHTTKVLTTTTTGFTATPSSSP------GTARTLP----VWISTTTTPTTRG 3282

Query: 466  IFTAPPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPF 525
                P        TP   + T T  ++ S+ T +S+T    Q   ++  PP  VP     
Sbjct: 3283 STVTPSSIPGTTHTPTVLTTTTTTVATGSMATPSSST----QTSGTTHTPP--VPNTTAT 3336

Query: 526  FKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFG--------INS 577
                +   ++P T    +T   S T     IT   PST ++  PA   G        ++S
Sbjct: 3337 THGRSLSPSSPHTVRTAWTSATSGTLGTTHIT--EPSTGTSHTPAATTGTTQHSTPALSS 3394

Query: 578  VSSSSVSTTTSTATAASQPFLFGAPQASAASFTPA--MGSIFQFGKPPALPTTTTVT--- 632
               SS +T +  +   + P    A   + A+ TP+    S      P + P TT VT   
Sbjct: 3395 PHPSSRTTESPPSPGTTTPGHTRATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTMGC 3454

Query: 633  ----TFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQP----------------- 671
                 +S+ L  + P     S  DF  + S +  +  A   QP                 
Sbjct: 3455 EPQCAWSEWLDYSYP-MPGPSGGDFDTY-SNIRAAGGAVCEQPLGLECRAQAQPGVPLRE 3512

Query: 672  -------TLTF-----SNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAK 719
                   +L F     +      F + F    +    +Y      PA  +        A 
Sbjct: 3513 LGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSS-------TAT 3565

Query: 720  PALTPSFGSSFTFGNSAAPAPA-TAPTPAPASTIKIVPAHVPTPIQPTFGGATHSAFGLK 778
            P+ TP      T   +AA   A T  T  P+ST    P   P P   T    T +A   K
Sbjct: 3566 PSSTPGTTWILTEQTTAATTTATTGSTAIPSST----PGTAPPPKVLTSTATTPTATSSK 3621

Query: 779  ATASAFGAPASSQPAFGGS---TAVFSFGAATSSGFGAT-----TQTASSGSSSSVFGST 830
            AT+S+    A++ P    +   +   SF    S   G T       T    + S++  S+
Sbjct: 3622 ATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPEQTTTPMATMSTIHPSS 3681

Query: 831  TP-----SPFTFGGSAAPAGSGSFGINVATPGSS-----ATTGAFSFGAGQSGSTATSTP 880
            TP     S      +     + S     +TPG++      TT A +  A    +T +STP
Sbjct: 3682 TPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTP 3741

Query: 881  FTGGL--------------GQNALGTTGQSTPFAFNVGSTTESKP-VFGGTATPTFGQNT 925
             T  +              G  A  ++ ++T     V ++T + P V    ATP     +
Sbjct: 3742 GTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTPTVISSRATP-----S 3796

Query: 926  PAPGVGTSGSSLSFGASSAPAQGFVGVGPFGSAAPSFSIG 965
             +PG  T+  +L   A++  A          +A PS S+G
Sbjct: 3797 SSPGTATALPALRSTATTPTATSV-------TAIPSSSLG 3829



 Score = 82.0 bits (201), Expect = 2e-15
 Identities = 154/638 (24%), Positives = 228/638 (35%), Gaps = 116/638 (18%)

Query: 392  PPTTLLGLIPAPSMVPATD-------TKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQ 444
            P T        PS  P T        T A  T    +   P +T   +P PK      T 
Sbjct: 2579 PSTPATSSTATPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTTTATT 2638

Query: 445  NTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAP 504
             T  SS A P++S  +       TA P       TP   SVT     SSSL TT +  + 
Sbjct: 2639 PTVTSSKATPSSSPGTA------TALPALRSTATTPTATSVTPIP--SSSLGTTWTRLSQ 2690

Query: 505  TFQPVFS-SMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPST 563
            T  P  + S   P+S P  A     T   ATA TT A       S+T   A  T    +T
Sbjct: 2691 TTTPTATMSTATPSSTPETA--HTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTT 2748

Query: 564  DSA--SKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQA-------SAASFTPAMG 614
             +   + P+   G        +STTT+  T  S       P         +  + T A G
Sbjct: 2749 TTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATG 2808

Query: 615  SIFQFGK---------PPALPTTTTVTTFSQSLPTAVP-TATSSSAADFSGFGSTLATSA 664
            S+               P +P  T  TT  +SLP + P T  ++  +  SG   T   + 
Sbjct: 2809 SMATPSSSTQTSGTTHTPPVP-NTMATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITE 2867

Query: 665  PATSSQPTLT----FSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKP 720
            P+T +  TL      +  STP  + P  SS  +  P  PG    P    A  +    A P
Sbjct: 2868 PSTVTSHTLAATTGTTQHSTPALSSPHPSSRTTESPPSPGTT-TPGHTTATSRTTATATP 2926

Query: 721  ALTPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVPAH--------------VPTP---- 762
            + T +        ++  P   ++PT AP +T+  +                 +P P    
Sbjct: 2927 SKTRT--------STLLP---SSPTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSGGD 2975

Query: 763  ------IQPTFGGATHSAFGLKATASA------------------FGAPASSQPAFGGST 798
                  I+   G       GL+  A A                  FG    ++   G   
Sbjct: 2976 FDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFK 3035

Query: 799  AVFSFGAAT-SSGFG---ATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVA 854
              F++        +G   +T  T+S+   SS  G+T         +     +GS     +
Sbjct: 3036 MCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTTESTGSTATPSS 3095

Query: 855  TPGSS------ATTGAFSFGAGQSGSTATSTPFTGG------LGQNALGTTGQSTPFAFN 902
            TPG++      +TT   +   G S +TA+ST  T G             T+ ++TPF+ +
Sbjct: 3096 TPGTTWILTEPSTTATVTVPTG-STATASSTQATAGTPHVSTTATTPTVTSSKATPFS-S 3153

Query: 903  VGSTTESKPVFGGTATPTFGQNT--PAPGVGTSGSSLS 938
             G+ T    +     TPT    T  P+  +GT+ + LS
Sbjct: 3154 PGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLS 3191



 Score = 77.0 bits (188), Expect = 8e-14
 Identities = 126/560 (22%), Positives = 186/560 (33%), Gaps = 39/560 (6%)

Query: 126  SSSMSSLTGAYTSGIPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRSQTPER 185
            +S+ +  T    + IPSS+     +    T           PSS+P ++  S+   T   
Sbjct: 4785 TSTATKSTATSVTPIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTVLTTKAT 4844

Query: 186  PAKKIREEELCHHSSSSTPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQRKRKVQL 245
              +          + SSTP      ++   AA TT      +   STPG++         
Sbjct: 4845 TTRATSSTS----TPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTELTTT 4900

Query: 246  LPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETPPTTQ 305
              +      T  P    G +    +       ++          S A ++S   T  T  
Sbjct: 4901 ATTTASTGSTATPSSTPGTTWILTEPSTTATVTVP-------TGSTATASSTQATAGTPH 4953

Query: 306  PSFTFTLPAAATASPPTSLLAPSTNPLLESLKKMQTPP---SLPPCPESAGAATTEALSP 362
             S T T P   T+S  T   +P T   L +L+   T P   S    P S+   T   LS 
Sbjct: 4954 VSTTATTPTV-TSSKATPSSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQ 5012

Query: 363  PKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTT-LLGLIPAPSMVPAT--DTKAPPTLQA 419
              TP+         S P  +  S    +   TT   G +  PS  P T   TK P T   
Sbjct: 5013 TTTPTATMSTATPSSTPETVHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTT 5072

Query: 420  ETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPT 479
                 P ++   +  P  +    T +T  +S + P  +  S +   + T    +     T
Sbjct: 5073 GFTATPSSSPGTALTPPTTTPMSTMSTIHTS-STPETTHTSTV---LTTTATMTRATNST 5128

Query: 480  PPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTT 539
                S   T    + L TT +TTA T      S  P  +  L  P    T    T  T T
Sbjct: 5129 ATPSSTLGTTRILTELTTTATTTAATGSTATLSSTPGTTWILTEPSTIATVMVPTGSTAT 5188

Query: 540  APLFTGLASATSAVAPITSASPSTDSASKPAFGFGI--------NSVSSSSVSTTTSTAT 591
            A    G A     V  + +   +T S    +   G         +S+ + SVST +S+  
Sbjct: 5189 ASSTLGTAHTPKVVTTMATMPTATASTVPSSSTVGTTRTPAVLPSSLPTFSVSTVSSSVL 5248

Query: 592  AASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAA 651
               +P  F +   S   F  A G  F  G+     T      F          A  +   
Sbjct: 5249 TTLRPTGFPSSHFSTPCFCRAFGQFFSPGEVIYNKTDRAGCHF---------YAVCNQHC 5299

Query: 652  DFSGFGSTLATSAPATSSQP 671
            D   F     TS P  SS P
Sbjct: 5300 DIDRFQGACPTSPPPVSSAP 5319



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 119/491 (24%), Positives = 165/491 (33%), Gaps = 77/491 (15%)

Query: 529  TTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTS 588
            TT   TA TTT          TS+  P  + +P   + + P    G+ S   +S   T +
Sbjct: 2306 TTELETATTTTTQALFSTPQPTSS--PGLTRAPPASTTAVPTLSEGLTSPRYTSTLGTAT 2363

Query: 589  TATAASQPFLFGAPQASAASFTPAMGSIFQFGKPP--ALPTTT-TVTTFSQSLP-TAVPT 644
            T          G P   A S  P +  +     P   ALP TT ++ T+  S P T  PT
Sbjct: 2364 T----------GGPTTPAGSTEPTVPGVATSTLPTRSALPGTTGSLGTWRPSQPPTLAPT 2413

Query: 645  ATSSSAADFSGFGSTLATSAPATSSQPTLTFS-NTSTPTFNIPFGSSAKSPLPSYPGANP 703
              ++S A  +G  ST +     TS  PTLT   +TS    + P   +  SPL      N 
Sbjct: 2414 TMATSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTETTMSPL-----TNT 2468

Query: 704  QPAFGAAEGQPP-------GAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVP 756
              + G    QP            P    + G   TF N  A        P    +I+   
Sbjct: 2469 TTSQGTTRCQPKCEWTEWFDVDFPTSGVAGGDMETFENIRAAGGKMCWAP---KSIECRA 2525

Query: 757  AHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFG--------------GSTAVFS 802
             + P       G     +     T             F                ST   S
Sbjct: 2526 ENYPEVSIDQVGQVLTCSLETGLTCKNEDQTGRFNMCFNYNVRVLCCDDYSHCPSTPATS 2585

Query: 803  FGAATSSGFGAT----------TQTASSGSSSSVFGS--TTPSPFTFGGSAA-PAGSGSF 849
              A  SS  G T          T TAS+GS+++   +  T P P     +A  P  + S 
Sbjct: 2586 STATPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTTTATTPTVTSSK 2645

Query: 850  GINVATPGSSATTGAFSFGAGQSGSTATS-TPFTGG--------LGQNALGTTGQSTPFA 900
                ++PG++    A    A  +  TATS TP            L Q    T   ST   
Sbjct: 2646 ATPSSSPGTATALPALRSTA--TTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATP 2703

Query: 901  FNVGSTTESKPVFGGTATPTFGQNTPAPGVGTSGSSLSFGASSAPAQGFVGVGPFGSAAP 960
             +   T  +  V   TAT T    + A    T G++ +    +    GF       +A P
Sbjct: 2704 SSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGF-------TATP 2756

Query: 961  SFSIGAGSKTP 971
            S S G     P
Sbjct: 2757 SSSPGTALTPP 2767


>gi|239752594 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 673

 Score =  110 bits (274), Expect = 8e-24
 Identities = 152/617 (24%), Positives = 240/617 (38%), Gaps = 69/617 (11%)

Query: 223 KKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWF 282
           + Q+S+  +   S    KR    +P R     TLP    +    TA       +ASL   
Sbjct: 78  RMQSSSLLTRTPSMASLKR----MPPRASRTRTLPRASLMRRPSTASLTRSPSRASLT-- 131

Query: 283 NQALEDKSDAASNSVTETPPTTQPSFTFTLPAAATASPPTSLLA--PSTNPLLESLKKMQ 340
                     AS S+T   P+T  + T    A+ T +PP + L   PST  L  +  +  
Sbjct: 132 -----TTPSRASLSMT---PSTAAALTMPSRASLTRTPPRASLTMTPSTASLTRTPPRA- 182

Query: 341 TPPSLPPCPESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLI 400
           +P  +P      G  +T +L+   + + +    LS++ P G  P  S    PP   L ++
Sbjct: 183 SPTGMPSRTSPTGMPSTASLTKMDSTASITRT-LSRASPTGTPPRASPTGSPPRASLSMM 241

Query: 401 PAPSMVPATDTKAPPT--LQAETATKPQATSA------------PSPAPKQSFLFGTQNT 446
           P+ +++  T  +A PT  L   + TK  +T++            P+  P ++ L  T +T
Sbjct: 242 PSTALLIRTPPRASPTGMLSRTSLTKMDSTASITRTPSRPSTASPTGTPSRASLSMTPST 301

Query: 447 SPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPPGPSVTATA--------PSSSSLPTT 498
           +      P AS    + +   T    +     TPP  S+T T         PS++S   T
Sbjct: 302 ASLMRMLPRASPTGMLSRTSLTKMDSTASISRTPPRASITRTPSRASPTGKPSTASPTGT 361

Query: 499 TSTTAPTFQPVFSSMGPPASVPLPA---PFFKQTTTPATAPTTTAPLF---TGLASATSA 552
            S  +PT  P  +S+   +S   P    P    T TP+TA  T  P     TG+ S TS 
Sbjct: 362 PSRASPTGSPSTASLTGLSSTASPTGTPPRASPTGTPSTASLTRKPPRASPTGMLSRTSI 421

Query: 553 VAPITSASPS-----TDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLF---GAPQA 604
               ++ASP+           P       + S +S + T STA+    P      G+P  
Sbjct: 422 TKMDSTASPTRTPPRASPTGTPPRASPTGTPSRASPTGTQSTASPTGSPSTASPTGSPST 481

Query: 605 SAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATSA 664
           ++ + +P+  S+ +     +L    +  + +++   A PT T S+A+      + LA  +
Sbjct: 482 ASPTGSPSRASLTRTPSRASLTKMESTASITRTPSRASPTWTPSTASPTGSPSTALAMGS 541

Query: 665 PATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKPALTP 724
           P   S+  LT + +       P  S A    PS       P+       PP A+ P   P
Sbjct: 542 P---SRAALTRTPSRASLTRTP--SRASLTTPSRASLTRTPSTVLLTRMPPSAS-PTGMP 595

Query: 725 SFGSS--------FTFGNSAAPAPATAPTPAPAST-IKIVPAHVPTPIQPTFGGATHSAF 775
           S  S          T  +S A    T P  +P  T  +  P   P    PT      S  
Sbjct: 596 SRTSPTGMPSSALLTKMDSTASITRTPPRASPTETPPRASPTGTPPRASPTGTPPRASPT 655

Query: 776 GLKATASAFGAPASSQP 792
           G    AS  G P+ + P
Sbjct: 656 GTPPRASPTGTPSRASP 672



 Score =  108 bits (270), Expect = 2e-23
 Identities = 161/683 (23%), Positives = 253/683 (37%), Gaps = 103/683 (15%)

Query: 124 SRSSSMSSLTG----AYTSGIPSS-------SRNAIT-----SSYSSTRGISQLWKRNGP 167
           +R+ S +SLTG    A  +G PS+       SR ++T     +S   T  ++ L      
Sbjct: 14  TRTPSTASLTGTPSRASLTGTPSTASLMGTPSRASLTGTPPRASLKGTTSMASLMVSPSR 73

Query: 168 SSSPFSSPASSRSQTPER------PAKKIREEELCHHSSSSTPLAADKESQGEKAA-DTT 220
           +S      +S  ++TP        P +  R   L   S    P  A       +A+  TT
Sbjct: 74  ASLTRMQSSSLLTRTPSMASLKRMPPRASRTRTLPRASLMRRPSTASLTRSPSRASLTTT 133

Query: 221 PRKKQNSNSQSTPGSSGQRKR----------KVQLLPSRRGEQLTLPPPPQLGYSITAED 270
           P +   S + ST  +     R           + + PS      T P     G       
Sbjct: 134 PSRASLSMTPSTAAALTMPSRASLTRTPPRASLTMTPSTASLTRTPPRASPTGMPSRTSP 193

Query: 271 LDLEKKASLQWFNQALEDKSDAASNSVTETPPTTQPS------------FTFTLPAAATA 318
             +   ASL   +         +  S T TPP   P+             T  L      
Sbjct: 194 TGMPSTASLTKMDSTASITRTLSRASPTGTPPRASPTGSPPRASLSMMPSTALLIRTPPR 253

Query: 319 SPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALS-PPKTPSLLPPLGLSQS 377
           + PT +L+ ++   ++S   +   PS P      G  +  +LS  P T SL+  L   ++
Sbjct: 254 ASPTGMLSRTSLTKMDSTASITRTPSRPSTASPTGTPSRASLSMTPSTASLMRML--PRA 311

Query: 378 GPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAETATKPQATSAPSP--AP 435
            P G+L   S      T  +   P  + +  T ++A PT +  TA+     S  SP  +P
Sbjct: 312 SPTGMLSRTSLTKMDSTASISRTPPRASITRTPSRASPTGKPSTASPTGTPSRASPTGSP 371

Query: 436 KQSFLFGTQNTSPSSPAAPAAS-SASPMFKPIFTAPPKSEKEGP---------------- 478
             + L G  +T+  +   P AS + +P    +   PP++   G                 
Sbjct: 372 STASLTGLSSTASPTGTPPRASPTGTPSTASLTRKPPRASPTGMLSRTSITKMDSTASPT 431

Query: 479 -TPPGPSVTATAPSSSSLPT--------TTSTTAPTFQPVFSSM--GPPASVPLPAPF-F 526
            TPP  S T T P +S   T        T ST +PT  P  +S    P  + P  +P   
Sbjct: 432 RTPPRASPTGTPPRASPTGTPSRASPTGTQSTASPTGSPSTASPTGSPSTASPTGSPSRA 491

Query: 527 KQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTT 586
             T TP+ A  T       +    S  +P  + S ++ + S P+    + S S ++++ T
Sbjct: 492 SLTRTPSRASLTKMESTASITRTPSRASPTWTPSTASPTGS-PSTALAMGSPSRAALTRT 550

Query: 587 TSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTAT 646
            S A+    P        S AS T    ++     PP+            + PT +P+ T
Sbjct: 551 PSRASLTRTPSRASLTTPSRASLTRTPSTVLLTRMPPS------------ASPTGMPSRT 598

Query: 647 SSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAK-SPLPSYPGANPQP 705
           S +    S   + + ++A  T + P    S T TP    P G+  + SP  + P A+P  
Sbjct: 599 SPTGMPSSALLTKMDSTASITRTPPRA--SPTETPPRASPTGTPPRASPTGTPPRASP-- 654

Query: 706 AFGAAEGQPPGAAKPALTPSFGS 728
                 G PP  A P  TPS  S
Sbjct: 655 -----TGTPP-RASPTGTPSRAS 671



 Score = 99.4 bits (246), Expect = 1e-20
 Identities = 139/563 (24%), Positives = 229/563 (40%), Gaps = 47/563 (8%)

Query: 413 APPTLQAETA--TKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAP 470
           APPT     A  T+  +T++ +  P ++ L GT +T        A+   +P    +   P
Sbjct: 2   APPTRTPSRASPTRTPSTASLTGTPSRASLTGTPST--------ASLMGTPSRASLTGTP 53

Query: 471 PKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSS---MGPPASVPLPAPFFK 527
           P++  +G T     + +  PS +SL    S++  T  P  +S   M P AS     P   
Sbjct: 54  PRASLKGTTSMASLMVS--PSRASLTRMQSSSLLTRTPSMASLKRMPPRASRTRTLPRAS 111

Query: 528 QTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSA-SKPAFGFGINSVSSSSVSTT 586
               P+TA  T +P    L +  S  +   S +PST +A + P+      +   +S++ T
Sbjct: 112 LMRRPSTASLTRSPSRASLTTTPSRAS--LSMTPSTAAALTMPSRASLTRTPPRASLTMT 169

Query: 587 TSTATAASQP---FLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVP 643
            STA+    P      G P  ++ +  P+  S+ +     ++  T +  + + + P A P
Sbjct: 170 PSTASLTRTPPRASPTGMPSRTSPTGMPSTASLTKMDSTASITRTLSRASPTGTPPRASP 229

Query: 644 TATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANP 703
           T  S   A  S   ST         + PT   S TS    +     +     PS      
Sbjct: 230 TG-SPPRASLSMMPSTALLIRTPPRASPTGMLSRTSLTKMDSTASITRTPSRPSTASPTG 288

Query: 704 QPAFGAAEGQPPGAAKPALTPSFG-------SSFTFGNSAAPAPATAP------TPAPAS 750
            P+  +    P  A+   + P          +S T  +S A    T P      TP+ AS
Sbjct: 289 TPSRASLSMTPSTASLMRMLPRASPTGMLSRTSLTKMDSTASISRTPPRASITRTPSRAS 348

Query: 751 TI----KIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAA 806
                    P   P+   PT   +T S  GL +TAS  G P  + P    STA  +    
Sbjct: 349 PTGKPSTASPTGTPSRASPTGSPSTASLTGLSSTASPTGTPPRASPTGTPSTASLTRKPP 408

Query: 807 TSSGFGATTQTASSGSSSSVFGSTTP---SPFTFGGSAAPAGSGSFGINVATPGSSATTG 863
            +S  G  ++T+ +   S+   + TP   SP      A+P G+ S      T  +++ TG
Sbjct: 409 RASPTGMLSRTSITKMDSTASPTRTPPRASPTGTPPRASPTGTPSRASPTGTQSTASPTG 468

Query: 864 AFSFGAGQSGSTATSTPFTGGLGQNALGTTGQSTPFAFNVGSTTESKPVFGGTATPTFGQ 923
           + S  A  +GS +T++P TG   + +L  T      +     +T S       A+PT+  
Sbjct: 469 SPS-TASPTGSPSTASP-TGSPSRASLTRTPSRA--SLTKMESTASITRTPSRASPTWTP 524

Query: 924 NTPAPGVGTSGSSLSFGASSAPA 946
           +T +P  G+  ++L+ G+ S  A
Sbjct: 525 STASP-TGSPSTALAMGSPSRAA 546



 Score = 98.2 bits (243), Expect = 3e-20
 Identities = 170/672 (25%), Positives = 271/672 (40%), Gaps = 82/672 (12%)

Query: 296 SVTETPPTTQPSFTFTLPAAATASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAA 355
           S+T TP  ++ S T T   A+    P+      T P   SLK   +  SL   P  A   
Sbjct: 21  SLTGTP--SRASLTGTPSTASLMGTPSRASLTGTPPRA-SLKGTTSMASLMVSPSRASLT 77

Query: 356 TTEALSP-PKTPSL-----LPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPAT 409
             ++ S   +TPS+     +PP    ++     LP  S   +P T  L   P+ + +  T
Sbjct: 78  RMQSSSLLTRTPSMASLKRMPP----RASRTRTLPRASLMRRPSTASLTRSPSRASLTTT 133

Query: 410 DTKAPPTLQAETA---TKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPI 466
            ++A  ++   TA   T P   S     P+ S    T +T+  +   P AS   P   P 
Sbjct: 134 PSRASLSMTPSTAAALTMPSRASLTRTPPRASLTM-TPSTASLTRTPPRAS---PTGMPS 189

Query: 467 FTAPPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFF 526
            T+P          P  +      S++S+  T S  +PT  P  +S   P   P  A   
Sbjct: 190 RTSPTGM-------PSTASLTKMDSTASITRTLSRASPTGTPPRAS---PTGSPPRASLS 239

Query: 527 KQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTT 586
              +T     T      TG+ S TS +  + S +  T + S+P+      + S +S+S T
Sbjct: 240 MMPSTALLIRTPPRASPTGMLSRTS-LTKMDSTASITRTPSRPSTASPTGTPSRASLSMT 298

Query: 587 TSTATAA------------SQPFLFGAPQASAASFTPAMGSIFQF---GKPPALPTTTTV 631
            STA+              S+  L      ++ S TP   SI +      P   P+T + 
Sbjct: 299 PSTASLMRMLPRASPTGMLSRTSLTKMDSTASISRTPPRASITRTPSRASPTGKPSTASP 358

Query: 632 T-TFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTS--------TPT 682
           T T S++ PT  P     S A  +G  ST + +     + PT T S  S        +PT
Sbjct: 359 TGTPSRASPTGSP-----STASLTGLSSTASPTGTPPRASPTGTPSTASLTRKPPRASPT 413

Query: 683 FNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAP--AP 740
             +   S  K    + P   P  A  +  G PP A+ P  TPS  S     ++A+P  +P
Sbjct: 414 GMLSRTSITKMDSTASPTRTPPRA--SPTGTPPRAS-PTGTPSRASPTGTQSTASPTGSP 470

Query: 741 ATA-PTPAPASTIKIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTA 799
           +TA PT +P++     P   P+    T   +  S   +++TAS    P+ + P +  STA
Sbjct: 471 STASPTGSPSTA---SPTGSPSRASLTRTPSRASLTKMESTASITRTPSRASPTWTPSTA 527

Query: 800 VFSFGAATSSGFGATTQTASSGSSSSVFGSTTPS--PFTFGGSAAPAGSGSFGINVATPG 857
             +   +T+   G+ ++ A + + S    + TPS    T    A+   + S  +    P 
Sbjct: 528 SPTGSPSTALAMGSPSRAALTRTPSRASLTRTPSRASLTTPSRASLTRTPSTVLLTRMPP 587

Query: 858 SSATTGAFSFGAGQSGSTATSTPFTGGLGQ-NALGTTGQSTPFAFNVGSTTESKPVFGGT 916
           S++ TG        S ++ T  P +  L + ++  +  ++ P A    S TE+ P    T
Sbjct: 588 SASPTGM------PSRTSPTGMPSSALLTKMDSTASITRTPPRA----SPTETPPRASPT 637

Query: 917 ATPTFGQNTPAP 928
            TP     T  P
Sbjct: 638 GTPPRASPTGTP 649



 Score = 61.2 bits (147), Expect = 5e-09
 Identities = 116/524 (22%), Positives = 198/524 (37%), Gaps = 71/524 (13%)

Query: 513 MGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFG 572
           M PP   P  A     T TP+TA  T  P    L    S  + + + S ++ + + P   
Sbjct: 1   MAPPTRTPSRA---SPTRTPSTASLTGTPSRASLTGTPSTASLMGTPSRASLTGTPPRAS 57

Query: 573 F-GINSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTV 631
             G  S++S  VS + ++ T            +S  + TP+M S+ +   PP    T T+
Sbjct: 58  LKGTTSMASLMVSPSRASLTRMQ--------SSSLLTRTPSMASLKRM--PPRASRTRTL 107

Query: 632 TTFS-QSLPTAVPTATSSSAADFSGFGS----TLATSAPATSSQPTLTFSNTSTPTFNIP 686
              S    P+      S S A  +   S    ++  S  A  + P+      + P  ++ 
Sbjct: 108 PRASLMRRPSTASLTRSPSRASLTTTPSRASLSMTPSTAAALTMPSRASLTRTPPRASLT 167

Query: 687 FGSSAKSPLPSYPGANP--QPAFGAAEGQPPGAA--KPALTPSFGSSFTFGNSAAPAPAT 742
              S  S   + P A+P   P+  +  G P  A+  K   T S   + +  +     P  
Sbjct: 168 MTPSTASLTRTPPRASPTGMPSRTSPTGMPSTASLTKMDSTASITRTLSRASPTGTPPRA 227

Query: 743 APTPA-PASTIKIVPA-----HVPTPIQPTFGGATHSAF-------------GLKATASA 783
           +PT + P +++ ++P+       P    PT G  + ++                 +TAS 
Sbjct: 228 SPTGSPPRASLSMMPSTALLIRTPPRASPT-GMLSRTSLTKMDSTASITRTPSRPSTASP 286

Query: 784 FGAPASSQPAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSVFGSTTP----------- 832
            G P+ +  +   STA        +S  G  ++T+ +   S+   S TP           
Sbjct: 287 TGTPSRASLSMTPSTASLMRMLPRASPTGMLSRTSLTKMDSTASISRTPPRASITRTPSR 346

Query: 833 -SPFTFGGSAAPAGSGSFGINVATPGSSATTGAFSFGAGQSG----STATSTPFTGGLGQ 887
            SP     +A+P G+ S      +P +++ TG  S  A  +G    ++ T TP T  L +
Sbjct: 347 ASPTGKPSTASPTGTPSRASPTGSPSTASLTG-LSSTASPTGTPPRASPTGTPSTASLTR 405

Query: 888 N--ALGTTGQSTPFAF----NVGSTTESKPVFGGTATPTFGQNTPAPGVGTSGSSLSFGA 941
                  TG  +  +     +  S T + P    T TP     T  P   +  S     +
Sbjct: 406 KPPRASPTGMLSRTSITKMDSTASPTRTPPRASPTGTPPRASPTGTP---SRASPTGTQS 462

Query: 942 SSAPAQGFVGVGPFGSAAPSFSIGAGSKTPGARQRLQARRQHTR 985
           +++P        P GS  PS +   GS +  +  R  +R   T+
Sbjct: 463 TASPTGSPSTASPTGS--PSTASPTGSPSRASLTRTPSRASLTK 504



 Score = 36.6 bits (83), Expect = 0.12
 Identities = 75/317 (23%), Positives = 120/317 (37%), Gaps = 38/317 (11%)

Query: 102 PKPGSLKRGLNSQSSDDHLNKRSRSSSMSSLTGAYTSGIPSSSRNAITSSYSSTRGISQL 161
           P   SL  GL+S +S      R+  +   S T + T   P +S   + S  S T+  S  
Sbjct: 371 PSTASLT-GLSSTASPTGTPPRASPTGTPS-TASLTRKPPRASPTGMLSRTSITKMDSTA 428

Query: 162 WK-RNGPSSSPFSSPA-SSRSQTPERPAKKIREEELCHHSSSST------PLAADKESQG 213
              R  P +SP  +P  +S + TP R +    +       S ST      P  A      
Sbjct: 429 SPTRTPPRASPTGTPPRASPTGTPSRASPTGTQSTASPTGSPSTASPTGSPSTASPTGSP 488

Query: 214 EKAADT-TPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLD 272
            +A+ T TP +   +  +ST          +   PSR     T       G   TA  + 
Sbjct: 489 SRASLTRTPSRASLTKMESTAS--------ITRTPSRASPTWTPSTASPTGSPSTALAMG 540

Query: 273 LEKKASL-QWFNQALEDKSDAASN-------SVTETPPTTQPSFTFTLPAAATASPPTSL 324
              +A+L +  ++A   ++ + ++       S+T TP T        +P +A+ +   S 
Sbjct: 541 SPSRAALTRTPSRASLTRTPSRASLTTPSRASLTRTPSTV---LLTRMPPSASPTGMPSR 597

Query: 325 LAPSTNPLLESLKKM-------QTPPSLPPCPESAGAATTEALSPPKTPSLLPPLGLSQS 377
            +P+  P    L KM       +TPP   P  E+   A+     P  +P+  PP      
Sbjct: 598 TSPTGMPSSALLTKMDSTASITRTPPRASPT-ETPPRASPTGTPPRASPTGTPPRASPTG 656

Query: 378 GPPGLLPSPSFDSKPPT 394
            PP   P+ +     PT
Sbjct: 657 TPPRASPTGTPSRASPT 673


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score =  108 bits (270), Expect = 2e-23
 Identities = 206/903 (22%), Positives = 306/903 (33%), Gaps = 149/903 (16%)

Query: 45  ETVLSALKEKKKKRT---------VEEEDQIFLDGQENKRRRHDSSGSGHS--AFEPLVA 93
           E+  + +K+ KK RT         V +E    LD  + K    D+S + H+  +  P + 
Sbjct: 60  ESFCAEVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKIT 119

Query: 94  SGVPASFVPKPGSLKRGLNSQSSDDHLNKRSRSSSMSSLTGAYTSGIPSSSRNAITSSYS 153
           +  P +  P+P        S+ +   +NK +   +  + T   T+   S+     T+S  
Sbjct: 120 TAKPIN--PRPSLPPNSDTSKETSLTVNKETTVETKETTT---TNKQTSTDGKEKTTSAK 174

Query: 154 STRGISQLWKRN-GPSSSPFSSPASSRSQTPERPAKKIREEELCHHSSSSTPLAADKESQ 212
            T+ I +   ++  P+S   + P      T + PA    +E      + +TP        
Sbjct: 175 ETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEP-----TPTTP-------- 221

Query: 213 GEKAADTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLD 272
            ++ A TTP++   +  +S P +  +        P+      T P  P            
Sbjct: 222 -KEPASTTPKEPTPTTIKSAPTTPKEPA------PTTTKSAPTTPKEP------------ 262

Query: 273 LEKKASLQWFNQALEDKSDAASNSVTETPPTT--QPSFTFTLPAAATASPPTSLLAPSTN 330
                       A     + A  +  E  PTT  +P+ T T  A  T   P         
Sbjct: 263 ------------APTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA 310

Query: 331 PLLESLKKMQTPPSLPPCPESAGAATTEALSP--PKTPSLLPPLGLSQSGPPGLLPSPSF 388
           P         TP    P      A TT+  +P  PK P+   P   + + P    P+P+ 
Sbjct: 311 PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE--PAPTT 368

Query: 389 DSKP-PTTLLGLIPAPSMVPA-TDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNT 446
             +P PTT     P     PA T TK+ PT   E A  P  T +    PK+     T+  
Sbjct: 369 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPA--PTTTKSAPTTPKEPSPTTTKEP 426

Query: 447 SPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPPGPSVT---ATAPSSSSLPTTTSTTA 503
           +P++P  PA ++     KP  T P +     P  P P+ T   A        PTT   TA
Sbjct: 427 APTTPKEPAPTTPK---KPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 483

Query: 504 PTFQPVFSSMGP----PASVPLPAPFFKQTTTPATA--PTTTAPLFTGLASATSAVAPIT 557
           PT     +   P    P +   PAP   +   P T   PT T P      +   A AP T
Sbjct: 484 PTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPA-PTTPKAAAPNT 542

Query: 558 SASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIF 617
              P+  +  +PA        +    + TT   TA                         
Sbjct: 543 PKEPAPTTPKEPA------PTTPKEPAPTTPKETA------------------------- 571

Query: 618 QFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSN 677
                P  P  T  TT  +  PT   T    +  + +   +   TS       PT T   
Sbjct: 572 -----PTTPKGTAPTTLKEPAPT---TPKKPAPKELAPTTTKEPTSTTCDKPAPT-TPKG 622

Query: 678 TSTPTFNIPFGSSAKSPLPSYP-GANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSA 736
           T+  T   P  ++ K P P+ P G  P      A   P   A   L P+     T   S 
Sbjct: 623 TAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD 682

Query: 737 APAPATA----PT----PAPASTIKIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPA 788
            PAP T     PT    PAP +  K  P    TP   T   +T +    K   +   +P 
Sbjct: 683 KPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTT--TKEPTTIHKSPD 740

Query: 789 SSQPAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGS 848
            S P         +   +       TT+T ++        +TT    T            
Sbjct: 741 ESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEM---TTTAKDKTTERDLRTTPE-- 795

Query: 849 FGINVATPGSSATTGAFSFGAGQSGSTATSTPFTGGLGQNALGTTGQSTPFAFNVGSTTE 908
                A P  +  T   +    +S  TAT+T  T         TT  +TPF      TT 
Sbjct: 796 --TTTAAPKMTKETATTTEKTTESKITATTTQVTS-------TTTQDTTPFKITTLKTTT 846

Query: 909 SKP 911
             P
Sbjct: 847 LAP 849



 Score = 93.2 bits (230), Expect = 1e-18
 Identities = 153/673 (22%), Positives = 220/673 (32%), Gaps = 94/673 (13%)

Query: 287 EDKSDAASNSVTETPPTTQPS--------FTFTLPAAATASPPTSLLAPSTNPLLESLKK 338
           ++K +      T  PP    +        F  T P  +T    T     ST+P + + K 
Sbjct: 68  DNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTST----TQHNKVSTSPKITTAKP 123

Query: 339 MQTPPSLPPCPESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLG 398
           +   PSLPP  +++   +          +        Q+   G        S   T  + 
Sbjct: 124 INPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDG---KEKTTSAKETQSIE 180

Query: 399 LIPAPSMVPATDTKAPPTLQAETATK-PQATSAPSPAPKQSFLFGTQNTSPSSPAAPAAS 457
              A  + P +   A PT +AET TK P  T+   P P          T+P  PA+    
Sbjct: 181 KTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTP----------TTPKEPASTTPK 230

Query: 458 SASPMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPA 517
             +P          KS    P  P P+ T +AP++   P  T+T  P           P 
Sbjct: 231 EPTP-------TTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPA----------PT 273

Query: 518 SVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINS 577
           +   PAP    TTT   APTTT              AP T   P+  +  KPA       
Sbjct: 274 TPKEPAP----TTTKEPAPTTTKS------------APTTPKEPAPTTPKKPA------P 311

Query: 578 VSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKP-PALPTTTTVTTFSQ 636
            +    + TT      + P          A  TP   +     KP P  P     TT  +
Sbjct: 312 TTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKE 371

Query: 637 SLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLP 696
             PT     + ++  + +    T   SAP T+ +P  T + ++  T   P  ++ K P P
Sbjct: 372 PAPTTTKEPSPTTPKEPA---PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 428

Query: 697 SYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVP 756
           + P           E  P    KPA T              PAP T   PAP +T K  P
Sbjct: 429 TTP----------KEPAPTTPKKPAPT----------TPKEPAPTTPKEPAPTTTKKPAP 468

Query: 757 AHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAATSSGFGATTQ 816
              P    PT    T      K T +     A + P     T        T      TT 
Sbjct: 469 T-TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTP 527

Query: 817 TASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATTGAFSFGAGQSGSTA 876
              + ++       TP          PA +        TP  +A T             A
Sbjct: 528 EEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPA 587

Query: 877 TSTPFTGGLGQNALGTTGQSTPFAFNVGSTTESKPVFGGT----ATPTFGQNTPAPGVGT 932
            +TP      + A  TT + T    +  + T  K     T    A  T  +  P    GT
Sbjct: 588 PTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGT 647

Query: 933 SGSSLSFGASSAP 945
           + ++L   A + P
Sbjct: 648 APTTLKEPAPTTP 660



 Score = 83.2 bits (204), Expect = 1e-15
 Identities = 136/611 (22%), Positives = 222/611 (36%), Gaps = 65/611 (10%)

Query: 141 PSSSRNAITSSY----SSTRGISQLWKRNGPSSSPFSSPASSRSQ---TPERPAKKIREE 193
           P+++++A T++     ++T+      K   P+++   +P + +     TP++PA    +E
Sbjct: 390 PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKE 449

Query: 194 ELCHHSSSSTPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQ 253
                     P         +K A TTP++   +  + T  ++ ++      L     E+
Sbjct: 450 PAPTTPKEPAPTTT------KKPAPTTPKEPAPTTPKETAPTTPKK------LTPTTPEK 497

Query: 254 LTLPPPPQLGYSITAEDL---DLEKKASLQWFNQALEDKSDAASNSVTETPPTTQPSFTF 310
           L  P  P+     T E+L     E+         A      AA N+  E  PTT      
Sbjct: 498 LA-PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAP 556

Query: 311 TLPAAATASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALSPPKT----P 366
           T P     + P    AP+T          +  P+ P  P     A T    P  T    P
Sbjct: 557 TTPKEPAPTTPKET-APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKP 615

Query: 367 SLLPPLGLSQSGPPGLLPSPSFDSKP-PTTLLGLIPAPSMVPATDTK---APPTLQAETA 422
           +   P G + + P    P+P+   +P PTT  G  P     PA  T    AP  L   T 
Sbjct: 616 APTTPKGTAPTTPKE--PAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT 673

Query: 423 TKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPPG 482
             P +T++  PAP        + T+P++P  PA ++           PP +  E  TP  
Sbjct: 674 KGPTSTTSDKPAPTTP-----KETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTT 728

Query: 483 PSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPA--SVPLPAPFFKQTTTPATAPTTTA 540
                T   S    T   +  PT + + +S   P   +   PA    + TT A   TT  
Sbjct: 729 TKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTER 788

Query: 541 PLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFG 600
            L T   + T+A       + +T+  ++        S  +++ +  TST T  + PF   
Sbjct: 789 DLRTTPETTTAAPKMTKETATTTEKTTE--------SKITATTTQVTSTTTQDTTPFKIT 840

Query: 601 -------APQASAA----SFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSS 649
                  AP+ +      + T  M    +  KP    T +  TT     PT  P   +S+
Sbjct: 841 TLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTST 900

Query: 650 AADFS----GFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQP 705
               +        T  T    TS+ P L  ++              ++P       NP+ 
Sbjct: 901 KKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKS 960

Query: 706 A-FGAAEGQPP 715
              G AEG+ P
Sbjct: 961 EDAGGAEGETP 971


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score =  108 bits (270), Expect = 2e-23
 Identities = 206/903 (22%), Positives = 306/903 (33%), Gaps = 149/903 (16%)

Query: 45  ETVLSALKEKKKKRT---------VEEEDQIFLDGQENKRRRHDSSGSGHS--AFEPLVA 93
           E+  + +K+ KK RT         V +E    LD  + K    D+S + H+  +  P + 
Sbjct: 101 ESFCAEVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKIT 160

Query: 94  SGVPASFVPKPGSLKRGLNSQSSDDHLNKRSRSSSMSSLTGAYTSGIPSSSRNAITSSYS 153
           +  P +  P+P        S+ +   +NK +   +  + T   T+   S+     T+S  
Sbjct: 161 TAKPIN--PRPSLPPNSDTSKETSLTVNKETTVETKETTT---TNKQTSTDGKEKTTSAK 215

Query: 154 STRGISQLWKRN-GPSSSPFSSPASSRSQTPERPAKKIREEELCHHSSSSTPLAADKESQ 212
            T+ I +   ++  P+S   + P      T + PA    +E      + +TP        
Sbjct: 216 ETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEP-----TPTTP-------- 262

Query: 213 GEKAADTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLD 272
            ++ A TTP++   +  +S P +  +        P+      T P  P            
Sbjct: 263 -KEPASTTPKEPTPTTIKSAPTTPKEPA------PTTTKSAPTTPKEP------------ 303

Query: 273 LEKKASLQWFNQALEDKSDAASNSVTETPPTT--QPSFTFTLPAAATASPPTSLLAPSTN 330
                       A     + A  +  E  PTT  +P+ T T  A  T   P         
Sbjct: 304 ------------APTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA 351

Query: 331 PLLESLKKMQTPPSLPPCPESAGAATTEALSP--PKTPSLLPPLGLSQSGPPGLLPSPSF 388
           P         TP    P      A TT+  +P  PK P+   P   + + P    P+P+ 
Sbjct: 352 PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE--PAPTT 409

Query: 389 DSKP-PTTLLGLIPAPSMVPA-TDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNT 446
             +P PTT     P     PA T TK+ PT   E A  P  T +    PK+     T+  
Sbjct: 410 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPA--PTTTKSAPTTPKEPSPTTTKEP 467

Query: 447 SPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPPGPSVT---ATAPSSSSLPTTTSTTA 503
           +P++P  PA ++     KP  T P +     P  P P+ T   A        PTT   TA
Sbjct: 468 APTTPKEPAPTTPK---KPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 524

Query: 504 PTFQPVFSSMGP----PASVPLPAPFFKQTTTPATA--PTTTAPLFTGLASATSAVAPIT 557
           PT     +   P    P +   PAP   +   P T   PT T P      +   A AP T
Sbjct: 525 PTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPA-PTTPKAAAPNT 583

Query: 558 SASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIF 617
              P+  +  +PA        +    + TT   TA                         
Sbjct: 584 PKEPAPTTPKEPA------PTTPKEPAPTTPKETA------------------------- 612

Query: 618 QFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSN 677
                P  P  T  TT  +  PT   T    +  + +   +   TS       PT T   
Sbjct: 613 -----PTTPKGTAPTTLKEPAPT---TPKKPAPKELAPTTTKEPTSTTCDKPAPT-TPKG 663

Query: 678 TSTPTFNIPFGSSAKSPLPSYP-GANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSA 736
           T+  T   P  ++ K P P+ P G  P      A   P   A   L P+     T   S 
Sbjct: 664 TAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD 723

Query: 737 APAPATA----PT----PAPASTIKIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPA 788
            PAP T     PT    PAP +  K  P    TP   T   +T +    K   +   +P 
Sbjct: 724 KPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTT--TKEPTTIHKSPD 781

Query: 789 SSQPAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGS 848
            S P         +   +       TT+T ++        +TT    T            
Sbjct: 782 ESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEM---TTTAKDKTTERDLRTTPE-- 836

Query: 849 FGINVATPGSSATTGAFSFGAGQSGSTATSTPFTGGLGQNALGTTGQSTPFAFNVGSTTE 908
                A P  +  T   +    +S  TAT+T  T         TT  +TPF      TT 
Sbjct: 837 --TTTAAPKMTKETATTTEKTTESKITATTTQVTS-------TTTQDTTPFKITTLKTTT 887

Query: 909 SKP 911
             P
Sbjct: 888 LAP 890



 Score = 93.2 bits (230), Expect = 1e-18
 Identities = 153/673 (22%), Positives = 220/673 (32%), Gaps = 94/673 (13%)

Query: 287 EDKSDAASNSVTETPPTTQPS--------FTFTLPAAATASPPTSLLAPSTNPLLESLKK 338
           ++K +      T  PP    +        F  T P  +T    T     ST+P + + K 
Sbjct: 109 DNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTST----TQHNKVSTSPKITTAKP 164

Query: 339 MQTPPSLPPCPESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLG 398
           +   PSLPP  +++   +          +        Q+   G        S   T  + 
Sbjct: 165 INPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDG---KEKTTSAKETQSIE 221

Query: 399 LIPAPSMVPATDTKAPPTLQAETATK-PQATSAPSPAPKQSFLFGTQNTSPSSPAAPAAS 457
              A  + P +   A PT +AET TK P  T+   P P          T+P  PA+    
Sbjct: 222 KTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTP----------TTPKEPASTTPK 271

Query: 458 SASPMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPA 517
             +P          KS    P  P P+ T +AP++   P  T+T  P           P 
Sbjct: 272 EPTP-------TTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPA----------PT 314

Query: 518 SVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINS 577
           +   PAP    TTT   APTTT              AP T   P+  +  KPA       
Sbjct: 315 TPKEPAP----TTTKEPAPTTTKS------------APTTPKEPAPTTPKKPA------P 352

Query: 578 VSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKP-PALPTTTTVTTFSQ 636
            +    + TT      + P          A  TP   +     KP P  P     TT  +
Sbjct: 353 TTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKE 412

Query: 637 SLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLP 696
             PT     + ++  + +    T   SAP T+ +P  T + ++  T   P  ++ K P P
Sbjct: 413 PAPTTTKEPSPTTPKEPA---PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 469

Query: 697 SYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVP 756
           + P           E  P    KPA T              PAP T   PAP +T K  P
Sbjct: 470 TTP----------KEPAPTTPKKPAPT----------TPKEPAPTTPKEPAPTTTKKPAP 509

Query: 757 AHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAATSSGFGATTQ 816
              P    PT    T      K T +     A + P     T        T      TT 
Sbjct: 510 T-TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTP 568

Query: 817 TASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATTGAFSFGAGQSGSTA 876
              + ++       TP          PA +        TP  +A T             A
Sbjct: 569 EEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPA 628

Query: 877 TSTPFTGGLGQNALGTTGQSTPFAFNVGSTTESKPVFGGT----ATPTFGQNTPAPGVGT 932
            +TP      + A  TT + T    +  + T  K     T    A  T  +  P    GT
Sbjct: 629 PTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGT 688

Query: 933 SGSSLSFGASSAP 945
           + ++L   A + P
Sbjct: 689 APTTLKEPAPTTP 701



 Score = 83.2 bits (204), Expect = 1e-15
 Identities = 136/611 (22%), Positives = 222/611 (36%), Gaps = 65/611 (10%)

Query: 141  PSSSRNAITSSY----SSTRGISQLWKRNGPSSSPFSSPASSRSQ---TPERPAKKIREE 193
            P+++++A T++     ++T+      K   P+++   +P + +     TP++PA    +E
Sbjct: 431  PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKE 490

Query: 194  ELCHHSSSSTPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQ 253
                      P         +K A TTP++   +  + T  ++ ++      L     E+
Sbjct: 491  PAPTTPKEPAPTTT------KKPAPTTPKEPAPTTPKETAPTTPKK------LTPTTPEK 538

Query: 254  LTLPPPPQLGYSITAEDL---DLEKKASLQWFNQALEDKSDAASNSVTETPPTTQPSFTF 310
            L  P  P+     T E+L     E+         A      AA N+  E  PTT      
Sbjct: 539  LA-PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAP 597

Query: 311  TLPAAATASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALSPPKT----P 366
            T P     + P    AP+T          +  P+ P  P     A T    P  T    P
Sbjct: 598  TTPKEPAPTTPKET-APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKP 656

Query: 367  SLLPPLGLSQSGPPGLLPSPSFDSKP-PTTLLGLIPAPSMVPATDTK---APPTLQAETA 422
            +   P G + + P    P+P+   +P PTT  G  P     PA  T    AP  L   T 
Sbjct: 657  APTTPKGTAPTTPKE--PAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT 714

Query: 423  TKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPPG 482
              P +T++  PAP        + T+P++P  PA ++           PP +  E  TP  
Sbjct: 715  KGPTSTTSDKPAPTTP-----KETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTT 769

Query: 483  PSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPA--SVPLPAPFFKQTTTPATAPTTTA 540
                 T   S    T   +  PT + + +S   P   +   PA    + TT A   TT  
Sbjct: 770  TKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTER 829

Query: 541  PLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFG 600
             L T   + T+A       + +T+  ++        S  +++ +  TST T  + PF   
Sbjct: 830  DLRTTPETTTAAPKMTKETATTTEKTTE--------SKITATTTQVTSTTTQDTTPFKIT 881

Query: 601  -------APQASAA----SFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSS 649
                   AP+ +      + T  M    +  KP    T +  TT     PT  P   +S+
Sbjct: 882  TLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTST 941

Query: 650  AADFS----GFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQP 705
                +        T  T    TS+ P L  ++              ++P       NP+ 
Sbjct: 942  KKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKS 1001

Query: 706  A-FGAAEGQPP 715
               G AEG+ P
Sbjct: 1002 EDAGGAEGETP 1012


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score =  108 bits (270), Expect = 2e-23
 Identities = 138/542 (25%), Positives = 193/542 (35%), Gaps = 107/542 (19%)

Query: 298  TETPPTTQPSFTFTLPAAATASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATT 357
            + TP TT      +LP AA   PPT +   +   +++ + +      L P P  A A   
Sbjct: 1277 SSTPSTTPAPTGLSLPLAANQVPPTMV---NNTGVVKIVVRQAPRDGLTPVPPLAPA--- 1330

Query: 358  EALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTL 417
                 P+ PS         SG P +L      +  PT   G +P P++  A      PTL
Sbjct: 1331 -----PRPPS---------SGLPAVL------NPRPTLTPGRLPTPTLGTARAPMPTPTL 1370

Query: 418  QAETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSE--- 474
                  +P      SP+P+          S S+P A   + +SP+  P     P S    
Sbjct: 1371 -----VRPLLKLVHSPSPE---------VSASAPGAAPLTISSPLHVPSSLPGPASSPMP 1416

Query: 475  --KEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTP 532
                 P     S T + P SSSLP +  TT P           PAS PL  P     T  
Sbjct: 1417 IPNSSPLASPVSSTVSVPLSSSLPISVPTTLPA----------PASAPLTIPISAPLTVS 1466

Query: 533  ATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATA 592
            A+ P     +   LA    A     S +PS  S S  A   G+ +  S S S T      
Sbjct: 1467 ASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPG---- 1522

Query: 593  ASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAAD 652
               P L     A  +S  P + S          P  + V   + +L +  P+A + + A 
Sbjct: 1523 --HPLLL----APTSSHVPGLNST-------VAPACSPVLVPASALASPFPSAPNPAPAQ 1569

Query: 653  FSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEG 712
             S         APA+S+   L                      P  P A PQ A  A   
Sbjct: 1570 AS-------LLAPASSASQALA--------------------TPLAPMAAPQTAILAPSP 1602

Query: 713  QPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPASTI-KIVPAHVPTPI------QP 765
             PP A  P L PS G++    +S  P P  AP+  P +++    P   PTP+      Q 
Sbjct: 1603 APPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQT 1662

Query: 766  TFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAATSSGFGA-TTQTASSGSSS 824
                   S     A+        +  P  GGS+   +    T +  G   TQT S   +S
Sbjct: 1663 MLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPAS 1722

Query: 825  SV 826
            S+
Sbjct: 1723 SL 1724



 Score =  100 bits (250), Expect = 5e-21
 Identities = 142/557 (25%), Positives = 209/557 (37%), Gaps = 86/557 (15%)

Query: 301  PPTTQPSFTFTLPAAATASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEAL 360
            P    P  T T     T +  T+     T  L+  L K+   PS      + GAA     
Sbjct: 1339 PAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSASAPGAAPLTIS 1398

Query: 361  SPPKTPSLLP-----PLGLSQSGPPGLLPSP-------SFDSKPPTTLLGLIPAPSMVPA 408
            SP   PS LP     P+ +  S P   L SP          S  P ++   +PAP+  P 
Sbjct: 1399 SPLHVPSSLPGPASSPMPIPNSSP---LASPVSSTVSVPLSSSLPISVPTTLPAPASAPL 1455

Query: 409  TDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFT 468
            T   + P   + +      +  P  AP      G  + +PS     A+ SAS +   + T
Sbjct: 1456 TIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSG----ASPSASALTLGLAT 1511

Query: 469  APPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVF---SSMGPP-ASVPLPAP 524
            AP  S  + P  P       AP+SS +P   ST AP   PV    S++  P  S P PAP
Sbjct: 1512 APSLSSSQTPGHP----LLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAP 1567

Query: 525  FFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVS 584
               Q +  A A + +  L T LA   +    I + SP+   A  P               
Sbjct: 1568 --AQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVL------------- 1612

Query: 585  TTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPT 644
                    A  P   GA    A+S TP          P   P++T  T+ + + P   PT
Sbjct: 1613 --------APSP---GAAPVLASSQTPV---------PVMAPSSTPGTSLASASPVPAPT 1652

Query: 645  ATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQ 704
               + ++  +   + + +  P+ +S  TL  +    PT     G S+ S   S    NPQ
Sbjct: 1653 PVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTL----GGSSPSQTLSLGTGNPQ 1708

Query: 705  PAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTP----APASTIKIVPAHVP 760
              F         A+    TP+   S   G    P    +  P    APAS +   PAH  
Sbjct: 1709 GPFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAHTL 1768

Query: 761  TPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAATSSGFG---ATTQT 817
            T + P             +++++  APAS Q        V + G A +       A+TQ+
Sbjct: 1769 T-LAPA------------SSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAPASTQS 1815

Query: 818  ASSGSSSSVFGSTTPSP 834
             +S +SS V  ++  +P
Sbjct: 1816 PASQASSLVVSASGAAP 1832



 Score = 93.2 bits (230), Expect = 1e-18
 Identities = 132/485 (27%), Positives = 188/485 (38%), Gaps = 91/485 (18%)

Query: 300  TPPTTQPSFTFTLPAAATA--SPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATT 357
            +P  +  S T ++P +++   S PT+L AP++ PL         P S P    ++G A  
Sbjct: 1421 SPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLT-------IPISAPLTVSASGPALL 1473

Query: 358  EALSPPKTPSL--------LPPLGLSQSGPP---GLLPSPSFDS-KPPTTLLGLIPAPSM 405
             +++PP  P +        L P G S S      GL  +PS  S + P   L L P  S 
Sbjct: 1474 TSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSH 1533

Query: 406  VPATD-TKAP---PTLQAETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASP 461
            VP  + T AP   P L   +A      SAP+PAP Q+ L    +++  + A P A  A+P
Sbjct: 1534 VPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAP 1593

Query: 462  MFKPIFTAPPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPL 521
              +    AP       P PP   +   APS  + P   S+  P              VP+
Sbjct: 1594 --QTAILAP------SPAPPLAPLPVLAPSPGAAPVLASSQTP--------------VPV 1631

Query: 522  PAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSS 581
             AP    ++TP T+          LASA+   AP    +PS+     PA    + S   S
Sbjct: 1632 MAP----SSTPGTS----------LASASPVPAPTPVLAPSSTQTMLPA---PVPSPLPS 1674

Query: 582  SVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPA-LPTTTTVTTFSQSLPT 640
              ST T     A  P L G    S+ S T ++G+    G P    PT T   T + SL  
Sbjct: 1675 PASTQTLALAPALAPTLGG----SSPSQTLSLGT----GNPQGPFPTQTLSLTPASSL-- 1724

Query: 641  AVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFN--IPFGSSAKSPLPSY 698
             VPT   + +             AP     PT T S    P      P G +    L   
Sbjct: 1725 -VPTPAQTLSL------------APGPPLGPTQTLSLAPAPPLAPASPVGPAPAHTLTLA 1771

Query: 699  PGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVPAH 758
            P ++       A  Q      PA  P+ G +     + APA   +P    +S +      
Sbjct: 1772 PASSSASLLAPASVQTL-TLSPAPVPTLGPAAAQTLALAPASTQSPASQASSLVVSASGA 1830

Query: 759  VPTPI 763
             P P+
Sbjct: 1831 APLPV 1835



 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 90/317 (28%), Positives = 133/317 (41%), Gaps = 33/317 (10%)

Query: 302  PTTQPSFTFTLPAAATASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGA-ATTEAL 360
            P +  S     P A  A+P T++LAPS  P L  L      P L P P +A   A+++  
Sbjct: 1575 PASSASQALATPLAPMAAPQTAILAPSPAPPLAPL------PVLAPSPGAAPVLASSQTP 1628

Query: 361  SPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAE 420
             P   PS  P   L+ + P   +P+P+    P +T   ++PAP   P     +  TL   
Sbjct: 1629 VPVMAPSSTPGTSLASASP---VPAPTPVLAPSSTQT-MLPAPVPSPLPSPASTQTLALA 1684

Query: 421  TATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTP 480
             A  P    +   +P Q+   GT N  P  P      S +P    + T P ++    P P
Sbjct: 1685 PALAPTLGGS---SPSQTLSLGTGN--PQGPFPTQTLSLTPASSLVPT-PAQTLSLAPGP 1738

Query: 481  P-GPSVTAT-APSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTT 538
            P GP+ T + AP+    P +    AP      +     AS+  PA     T +PA  PT 
Sbjct: 1739 PLGPTQTLSLAPAPPLAPASPVGPAPAHTLTLAPASSSASLLAPASVQTLTLSPAPVPT- 1797

Query: 539  TAPLFTGLASATSAVAPITSASPSTDSASKPAFGFG-----INSVSSSSVS-TTTSTATA 592
                    A+ T A+AP ++ SP++ ++S      G     +  VS   VS     T T 
Sbjct: 1798 ----LGPAAAQTLALAPASTQSPASQASSLVVSASGAAPLPVTMVSRLPVSKDEPDTLTL 1853

Query: 593  ASQPFLFGAPQASAASF 609
             S P    +P ++A SF
Sbjct: 1854 RSGP---PSPPSTATSF 1867



 Score = 73.9 bits (180), Expect = 7e-13
 Identities = 179/727 (24%), Positives = 246/727 (33%), Gaps = 143/727 (19%)

Query: 312  LPAAATASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALSPPKTP----S 367
            L  A    PP     P   P+     KM+    L P P+  G  T   ++ P+ P     
Sbjct: 975  LEVATAPDPP-----PRPKPV-----KMKVNRMLQPVPKQEGR-TVVVVNNPRAPLGPVP 1023

Query: 368  LLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPA-PSMVPATDTKAP---PTLQAETAT 423
            + PP G   S  P   P P     P + ++   PA P ++PA+    P   P LQ  + +
Sbjct: 1024 VRPPPGPELSAQP--TPGPVPQVLPASLMVSASPAGPPLIPASRPPGPVLLPPLQPNSGS 1081

Query: 424  KPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPPGP 483
             PQ    PSP      L GT     S P  P  S      KP    PP   +  P PP  
Sbjct: 1082 LPQVL--PSPL---GVLSGT-----SRPPTPTLS-----LKP---TPPAPVRLSPAPPPG 1123

Query: 484  SVTA----TAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTT 539
            S +     T P   + P   +TT  T     ++   PA  P P          A  P+  
Sbjct: 1124 SSSLLKPLTVPPGYTFPPAAATTTSTTTATATTTAVPAPTPAPQRLILSPDMQARLPSGE 1183

Query: 540  APLFTGLAS-ATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVS-------TTTSTAT 591
                  LAS A   VA    + P T              V   +V              +
Sbjct: 1184 VVSIGQLASLAQRPVANAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVS 1243

Query: 592  AASQPFLFGAPQ--ASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAV----PTA 645
            A  Q  L   P   A   +  P  G       P + P+TT   T   SLP A     PT 
Sbjct: 1244 AGGQHHLISQPAHVALIQAVAPTPGPTPVSVLPSSTPSTTPAPT-GLSLPLAANQVPPTM 1302

Query: 646  TSSSA--------ADFSGFGSTLATSAPA-----------TSSQPTLTFSNTSTPTFNIP 686
             +++         A   G  + +   APA            + +PTLT     TPT    
Sbjct: 1303 VNNTGVVKIVVRQAPRDGL-TPVPPLAPAPRPPSSGLPAVLNPRPTLTPGRLPTPTL--- 1358

Query: 687  FGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTP 746
               +A++P+P+     P      +      A+ P   P   SS     S+ P PA++P P
Sbjct: 1359 --GTARAPMPTPTLVRPLLKLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMP 1416

Query: 747  AP---------ASTIKI---------VPAHVPTPIQ-----PTFGGATHSAFGLKATASA 783
             P         +ST+ +         VP  +P P       P     T SA G     S 
Sbjct: 1417 IPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSV 1476

Query: 784  FGAPASSQPAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSVFGSTTPS-PFTFGGSAA 842
                A   PA  G  ++   GA+ S    A+  T    ++ S+  S TP  P       A
Sbjct: 1477 TPPLAPVVPAAPGPPSLAPSGASPS----ASALTLGLATAPSLSSSQTPGHPLLL----A 1528

Query: 843  PAGSGSFGIN---------VATPGSS-----------ATTGAFSFGAGQSGSTATSTPFT 882
            P  S   G+N         V  P S+           A   A       S S A +TP  
Sbjct: 1529 PTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLA 1588

Query: 883  G-GLGQNALGTTGQSTPFA--FNVGSTTESKPVFGGTATPTFGQNTPAPGVGTSGSSLSF 939
                 Q A+     + P A    +  +  + PV   + TP       AP   T G+SL+ 
Sbjct: 1589 PMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPV---PVMAPS-STPGTSLA- 1643

Query: 940  GASSAPA 946
             AS  PA
Sbjct: 1644 SASPVPA 1650



 Score = 72.8 bits (177), Expect = 2e-12
 Identities = 125/504 (24%), Positives = 187/504 (37%), Gaps = 68/504 (13%)

Query: 166  GPSSSPFSSPASSRSQTPERPAKKIREEELCHHSSSSTPLAADKESQGEKAAD-TTPRKK 224
            GP+SSP   P SS   +P      +         SSS P++         +A  T P   
Sbjct: 1409 GPASSPMPIPNSSPLASPVSSTVSV-------PLSSSLPISVPTTLPAPASAPLTIPISA 1461

Query: 225  QNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQL---GYSITAEDLDLEKKASLQW 281
              + S S P           + P         P PP L   G S +A  L L        
Sbjct: 1462 PLTVSASGPA------LLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTL-------- 1507

Query: 282  FNQALEDKSDAASNSVTETPPTTQPSFTFTLPAAATASPPTSLLAPSTNPLLESLKKMQT 341
                    + A S S ++TP           P ++      S +AP+ +P+L     + +
Sbjct: 1508 ------GLATAPSLSSSQTPGHP----LLLAPTSSHVPGLNSTVAPACSPVLVPASALAS 1557

Query: 342  P-PSLP-PCPESA-----GAATTEALSPPKTPSLLPPLG-LSQSGPPGLLPSPSFDSKP- 392
            P PS P P P  A      ++ ++AL+ P  P   P    L+ S  P L P P     P 
Sbjct: 1558 PFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPG 1617

Query: 393  --PTTLLGLIPAPSMVPATDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNTSPSS 450
              P       P P M P++    P T  A  +  P  T   +P+  Q+ L     +   S
Sbjct: 1618 AAPVLASSQTPVPVMAPSS---TPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPS 1674

Query: 451  PAAPAASSASPMFKPIF--TAPPKSEKEGP-TPPGPSVTAT---APSSSSLPTTTSTTAP 504
            PA+    + +P   P    ++P ++   G   P GP  T T    P+SS +PT   T + 
Sbjct: 1675 PASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSL 1734

Query: 505  TFQPVFSSMGPPASVPL-PAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPST 563
               P    +GP  ++ L PAP     +    AP  T  L    +SA S +AP +  + + 
Sbjct: 1735 APGP---PLGPTQTLSLAPAPPLAPASPVGPAPAHTLTLAPASSSA-SLLAPASVQTLTL 1790

Query: 564  DSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPP 623
              A  P  G       + + ++T S A+ AS   +     AS A+  P    +    + P
Sbjct: 1791 SPAPVPTLGPAAAQTLALAPASTQSPASQASSLVV----SASGAAPLP----VTMVSRLP 1842

Query: 624  ALPTTTTVTTFSQSLPTAVPTATS 647
                     T     P+   TATS
Sbjct: 1843 VSKDEPDTLTLRSGPPSPPSTATS 1866



 Score = 58.2 bits (139), Expect = 4e-08
 Identities = 62/277 (22%), Positives = 94/277 (33%), Gaps = 11/277 (3%)

Query: 300  TPPTTQPSFTFTLPAAATASPPTSLLAPSTNPLLESLKKMQTPPSLPPC------PESAG 353
            TP +   +    +P   +A  P S   P T   +  L     P  +PPC      P  A 
Sbjct: 2446 TPASAPAAIPALVPVPVSAPVPISAPNPITILPVHILPSPPPPSQIPPCSSPACTPPPAC 2505

Query: 354  AATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKA 413
                    PP    L+ P      GPP +  S S  + P    LGL P   +  A    +
Sbjct: 2506 TPPPAHTPPPAQTCLVTPSSPLLLGPPSVPISASVTNLP----LGLRPEAELC-AQALAS 2560

Query: 414  PPTLQAETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKS 473
            P +L+  +    + +S     PK       +    S        SA  +     + P   
Sbjct: 2561 PESLELASVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPSAPSLTLEAGSIPNGQ 2620

Query: 474  EKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPA 533
            E+E P     +     P    LP   S +     P  ++   P   PL A    +  T A
Sbjct: 2621 EQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAASDEPLQEPLEADRTSEELTEA 2680

Query: 534  TAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPA 570
              PT++      L +A  A    +S++ S+     PA
Sbjct: 2681 KTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPA 2717



 Score = 53.9 bits (128), Expect = 7e-07
 Identities = 139/689 (20%), Positives = 224/689 (32%), Gaps = 100/689 (14%)

Query: 149  TSSYSSTRGISQLWKR--NGPSSSPFSSPASSRSQTPERPAKKIREEELCHHSSSSTPLA 206
            T++Y   + I +L+      PSSS   S      +T       I E+ LC  +     + 
Sbjct: 2197 TTAYFKQQTIRELFDMPLEEPSSSSVPSAPEEEEETVASKQTHILEQALCR-AEDEEDIR 2255

Query: 207  ADKESQGEKAADTTPRKKQNS------NSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPP 260
            A  +++ E+ A+     + +            PG+  +   + +   +   EQLT    P
Sbjct: 2256 AATQAKAEQVAELAEFNENDGFPAGEGEEAGRPGAEDEEMSRAEQEIAALVEQLT----P 2311

Query: 261  QLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETPPTTQPSFTFTLPAAATASP 320
               Y++   +  LE+  S +   QA E++ +AA   + +          F LP      P
Sbjct: 2312 IERYAMKFLEASLEE-VSREELKQA-EEQVEAARKDLDQAKEEV-----FRLPQEEEEGP 2364

Query: 321  PTSLLAP-STNPLLESLKKMQTPPSLPPC--PESAGAATTEALSPPKTPSLLPPLGLSQS 377
                 +   T        K    P  P     E    A  E      TP +      S +
Sbjct: 2365 GAGDESSCGTGGGTHRRSKKAKAPERPGTRVSERLRGARAETQGANHTPVISAHQTRSTT 2424

Query: 378  GPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAETATKPQATSAPSPAPKQ 437
             PP   P+     +P        P P   PA+   A P L     + P   SAP+P    
Sbjct: 2425 TPPRCSPARERVPRPA-------PRPRPTPASAPAAIPALVPVPVSAPVPISAPNPI--- 2474

Query: 438  SFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPK-SEKEGPTPPGPSVTATAPSSS--- 493
                 T       P+ P  S   P   P  T PP  +     TPP        PSS    
Sbjct: 2475 -----TILPVHILPSPPPPSQIPPCSSPACTPPPACTPPPAHTPPPAQTCLVTPSSPLLL 2529

Query: 494  ---SLPTTTSTT------APTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTA-PLF 543
               S+P + S T       P  +    ++  P S+ L +    +T++ +  P     P+ 
Sbjct: 2530 GPPSVPISASVTNLPLGLRPEAELCAQALASPESLELASVASSETSSLSLVPPKDLLPVA 2589

Query: 544  TGLASATSAVAPITSASPST--DSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGA 601
              +   +     +T ++PS   ++ S P    G    +  S   TT T     +      
Sbjct: 2590 VEILPVSEKNLSLTPSAPSLTLEAGSIPN---GQEQEAPDSAEGTTLTVLPEGEELPLCV 2646

Query: 602  PQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLA 661
             +++     P+  S     +P     T+   T +++ PT+ P               T  
Sbjct: 2647 SESNGLELPPSAASDEPLQEPLEADRTSEELTEAKT-PTSSPEKPQELV--------TAE 2697

Query: 662  TSAPATSSQPTLTFSNTST---PTFNIPFGSSAKSPLPSYPGANPQPAF----------- 707
             +AP+TSS  T +    S    P          +      PG  P P             
Sbjct: 2698 VAAPSTSSSATSSPEGPSPARPPRRRTSADVEIRGQGTGRPGQPPGPKVLRKLPGRLVTV 2757

Query: 708  --------------GAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPASTIK 753
                          GAA    PG ++ + +P   S  +     +  P   P  A  S   
Sbjct: 2758 VEEKELVRRRRQQRGAASTLVPGVSETSASPGSPSVRSMSGPESSPPIGGPCEAAPS--- 2814

Query: 754  IVPAHVPTPIQPTFGGATHSAFGLKATAS 782
               + +PTP Q  F    H   G+    S
Sbjct: 2815 ---SSLPTPPQQPFIARRHIELGVTGGGS 2840



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 64/252 (25%), Positives = 90/252 (35%), Gaps = 46/252 (18%)

Query: 314  AAATASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEAL-SPPKTP------ 366
            AA+T  P  S    S +P   S++ M  P S PP      AA + +L +PP+ P      
Sbjct: 2773 AASTLVPGVS--ETSASPGSPSVRSMSGPESSPPIGGPCEAAPSSSLPTPPQQPFIARRH 2830

Query: 367  -------------------SLLPPLGLSQSG-PPGLLPSPS-----FDSKPPTTLLGLIP 401
                               ++ PP    + G PP    SP+      D  P +TL G   
Sbjct: 2831 IELGVTGGGSPENGDGALLAITPPAVKRRRGRPPKKNRSPADAGRGVDEAPSSTLKGKTN 2890

Query: 402  APSMVPATDTK--APPTLQAETATKPQATSA-----PSP--APKQSFLFGTQNTSPSSPA 452
                VP  +T   A P L+ +    PQ         P+P  +P +    G    +   P 
Sbjct: 2891 GADPVPGPETLIVADPVLEPQLIPGPQPLGPQPVHRPNPLLSPVEKRRRGRPPKARDLPI 2950

Query: 453  APAASSASPMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSS 512
                SSA        T PP      P  P P +    P+++   T T+ T  T  P    
Sbjct: 2951 PGTISSAGDGNSESRTQPPPHPS--PLTPLPPLLV-CPTATVANTVTTVTISTSPPKRKR 3007

Query: 513  MGPPASVPLPAP 524
              PP + P P P
Sbjct: 3008 GRPPKNPPSPRP 3019



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 72/328 (21%), Positives = 115/328 (35%), Gaps = 47/328 (14%)

Query: 490  PSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASA 549
            P  S+  T ++TT P   P    +  PA  P P        TPA+AP           +A
Sbjct: 2413 PVISAHQTRSTTTPPRCSPARERVPRPAPRPRP--------TPASAP-----------AA 2453

Query: 550  TSAVAPITSASPSTDSASKPAFGFGINSVSS----SSVSTTTSTA----TAASQPFLFGA 601
              A+ P+  ++P   SA  P     ++ + S    S +   +S A     A + P     
Sbjct: 2454 IPALVPVPVSAPVPISAPNPITILPVHILPSPPPPSQIPPCSSPACTPPPACTPPPAHTP 2513

Query: 602  PQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSL-PTAVPTATSSSAADFSGFGSTL 660
            P A     TP+   +     PP++P + +VT     L P A   A + ++ +     S  
Sbjct: 2514 PPAQTCLVTPSSPLLL---GPPSVPISASVTNLPLGLRPEAELCAQALASPESLELASVA 2570

Query: 661  ATSAPATSSQPTLTFSNTSTPTFNI--------PFGSSAKSPLPSYPGANPQPAFGAAEG 712
            ++   + S  P       +     +        P   S      S P    Q A  +AEG
Sbjct: 2571 SSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPSAPSLTLEAGSIPNGQEQEAPDSAEG 2630

Query: 713  Q-----PPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVPAHVPT--PIQP 765
                  P G   P             ++A+  P   P  A  ++ ++  A  PT  P +P
Sbjct: 2631 TTLTVLPEGEELPLCVSESNGLELPPSAASDEPLQEPLEADRTSEELTEAKTPTSSPEKP 2690

Query: 766  TFGGATHSAFGLKATASAFGAPASSQPA 793
                 T        ++SA  +P    PA
Sbjct: 2691 Q-ELVTAEVAAPSTSSSATSSPEGPSPA 2717



 Score = 34.3 bits (77), Expect = 0.59
 Identities = 73/310 (23%), Positives = 97/310 (31%), Gaps = 25/310 (8%)

Query: 665  PATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKPALTP 724
            P  S+QPT        P   +   S A  PL   P + P         QP   + P + P
Sbjct: 1030 PELSAQPTPGPVPQVLPASLMVSASPAGPPL--IPASRPPGPVLLPPLQPNSGSLPQVLP 1087

Query: 725  SFGSSFTFGNSAAPAPATAPTPAPASTIKIVPAHVP------TPIQ-------PTFGGAT 771
            S       G S  P P  +  P P + +++ PA  P       P+        P     T
Sbjct: 1088 S-PLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAPPPGSSSLLKPLTVPPGYTFPPAAATT 1146

Query: 772  HSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSVFGSTT 831
             S     AT +A  AP    PA           A   SG   +    +S +   V  +  
Sbjct: 1147 TSTTTATATTTAVPAPT---PAPQRLILSPDMQARLPSGEVVSIGQLASLAQRPVANAGG 1203

Query: 832  PSPFTF---GGSAAPAGSGSFGINVATPGSSATTGAFSFGAGQSGSTATSTPFTGGLGQN 888
              P TF   G      G+    + V  P            AG       S P    L Q 
Sbjct: 1204 SKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVSAG-GQHHLISQPAHVALIQ- 1261

Query: 889  ALGTTGQSTPFAFNVGSTTESKPVFGGTATPTFGQNTPAPGVGTSGSSLSFGASSAPAQG 948
            A+  T   TP +    ST  + P   G + P      P   V  +G  +      AP  G
Sbjct: 1262 AVAPTPGPTPVSVLPSSTPSTTPAPTGLSLPLAANQVPPTMVNNTG-VVKIVVRQAPRDG 1320

Query: 949  FVGVGPFGSA 958
               V P   A
Sbjct: 1321 LTPVPPLAPA 1330


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score =  107 bits (268), Expect = 4e-23
 Identities = 214/928 (23%), Positives = 337/928 (36%), Gaps = 109/928 (11%)

Query: 78   HDSSGSGHSAFEPLVASGVPASFVPKPGSLKRGLNSQSSDDHLNKRSRSSSMSSLTGAYT 137
            H S+GS H+   P       A    + G      +  SS D +     ++S        +
Sbjct: 1807 HSSTGSPHTTLSP-------AGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTS 1859

Query: 138  SGIPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSP-ASSRSQTPERPAKK-IREEEL 195
             G PSS+     S+ S+T G      R+  S++  SSP A++ + +P R     + EE  
Sbjct: 1860 HGSPSSTPTTHFSASSTTLG------RSEESTTVHSSPVATATTPSPARSTTSGLVEEST 1913

Query: 196  CHHSS-SSTPLAADKESQGEKAADTTPRKKQNSNSQ---STPGSSGQRKRKVQLLPSRRG 251
             +HSS  ST      ES          R   +S +    S P ++     +     S  G
Sbjct: 1914 AYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPG 1973

Query: 252  EQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETPPTTQPSF--T 309
               T   P     S  +E+            + A     DA    V     TT      +
Sbjct: 1974 STATTHFPDSSTTSGRSEE------------STASHSSQDATGTIVLPARSTTSVLLGES 2021

Query: 310  FTLPAAATASPPTSLLAPSTNP-LLESLKKMQTPPSLPPCPESAGAATTEALSPPKTPSL 368
             T P ++ +   T+L   +T P L E      + P  P    S  + T+  +S   T S 
Sbjct: 2022 TTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSH 2081

Query: 369  LPPLGLSQSGPPGLLPSPSFD-------SKPPTTLLGLIPAPSMVPATDTKAPPTLQAET 421
              P     +  P    +P          S P +T   L+PA     +T T  P      +
Sbjct: 2082 SRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPA-----STTTSGPSQESTTS 2136

Query: 422  ATKPQAT-SAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTP 480
             + P +T +A SP    +  FG ++T+  S      ++  P           S +   + 
Sbjct: 2137 HSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSST 2196

Query: 481  PGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTT---TPATAPT 537
              P  T +  SS+S      +TA    P  +   P       AP  + TT   +P + PT
Sbjct: 2197 GSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPT 2256

Query: 538  TTAPLFTGLASATSAVAPITSASPSTD-----SASKPAFGFGINSVSSSSV--------- 583
            T  P  +   S  S  + I  +SP        SA     G G ++ S  S          
Sbjct: 2257 THFPA-SSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLP 2315

Query: 584  -STTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAV 642
             STTT   + AS  F + +P++   + +PA  +    G+      +   +T S   P + 
Sbjct: 2316 GSTTTPGLSEASTTF-YSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPAST 2374

Query: 643  PT---ATSSSAADFSGFGSTLATSAPAT------SSQPTLTFSNTSTPTFNIPFGSSAKS 693
             T   +  S+    S  GST  T  P T        +PT   S  ++    +    S  S
Sbjct: 2375 TTPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTS 2434

Query: 694  PLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPASTIK 753
             L     A P    G+      G      T   G   T   S++ +  T  +PA ++T  
Sbjct: 2435 GLTEESTAFP----GSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSG 2490

Query: 754  IVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAATSSGFGA 813
            +V    P+ + P+    T +  G   T S      +   +     A  S    TSSG   
Sbjct: 2491 LVGESTPSRLSPS-STETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSE 2549

Query: 814  TTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATT----GAFSFGA 869
             + T+ S   S+    TT  P     +  P  S     + ++PGS+ TT       + G 
Sbjct: 2550 ESSTSHSQPGST---HTTAFP---DSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGP 2603

Query: 870  GQSGSTATSTPFTGGLGQNALGTTGQSTPFAFNVGSTT-ESKPVFGGTATPTFGQNTPAP 928
             Q  +T+ S+P   G    AL + G +T  +F   STT  S P  G T T  F  +T + 
Sbjct: 2604 SQESTTSHSSP---GSTDTAL-SPGSTTALSFGQESTTFHSSP--GSTHTTLFPDSTTSS 2657

Query: 929  GV-----------GTSGSSLSFGASSAP 945
            G+           G+  ++LS  +S++P
Sbjct: 2658 GIVEASTRVHSSTGSPRTTLSPASSTSP 2685



 Score =  101 bits (252), Expect = 3e-21
 Identities = 195/866 (22%), Positives = 315/866 (36%), Gaps = 104/866 (12%)

Query: 141  PSSSRNAITSSYSSTRGISQLWKRNGPSSSPF-SSPASSRSQTPERPAKKIREEELCHHS 199
            P+S+   + +  S+T G+++        S+ F  SPAS+++  P         EE     
Sbjct: 2419 PASTHTTLFTEDSTTSGLTE-------ESTAFPGSPASTQTGLPATLTTADLGEESTTFP 2471

Query: 200  SSS----TPLAADKESQGEKAADTTPRKKQNSNSQST-----PGSSGQRKRKVQLLPSRR 250
            SSS    T L+  + +      ++TP +   S++++T     P +    ++      S R
Sbjct: 2472 SSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPR 2531

Query: 251  GEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETPPTTQPSFTF 310
                TL P       ++ E      +        A  D +     S   T   + P  T 
Sbjct: 2532 SPDATLSPATTTSSGVSEESSTSHSQPG-STHTTAFPDSTTTPGLSRHSTTSHSSPGSTD 2590

Query: 311  T--LPAAATASPPT--------------SLLAPSTNPLL----ESLKKMQTPPS-----L 345
            T  LPA+ T S P+              + L+P +   L    ES     +P S      
Sbjct: 2591 TTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLF 2650

Query: 346  PPCPESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLL-PSPSFDSKPPTTLLGLIPAPS 404
            P    S+G           T S    L  + S  PGL   S +F + P +T     P+P 
Sbjct: 2651 PDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPAST--HTTPSP- 2707

Query: 405  MVPATDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFK 464
              P+T T   P  ++ T  +   ++  +  P  S   G    S    ++P AS  +P   
Sbjct: 2708 --PSTATA--PVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSA 2763

Query: 465  PIFTAPPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAP 524
               T+           PG +   T P S++ P   S  + TF   +SS   P +   PA 
Sbjct: 2764 HSTTSGRGESTTSRISPGSTEITTLPGSTTTPGL-SEASTTF---YSSPRSPTTTLSPA- 2818

Query: 525  FFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVS 584
                T+      +TT+    G  S  S V+P ++ +P     S   +     S  ++   
Sbjct: 2819 --SMTSLGVGEESTTSRSQPG--STHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFP 2874

Query: 585  TTTSTATAASQPFLFGAPQASAAS--FTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAV 642
             +T+T+    +P  F +  AS  +  FT    +     +  A P +   T     LP  +
Sbjct: 2875 RSTTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPAST--QTGLPATL 2932

Query: 643  PTAT--SSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPG 700
             TA     S    S  GST  T +PA S+   L     STP+   P  S+  + LP  P 
Sbjct: 2933 TTADLGEESTTFPSSSGSTGTTLSPARSTTSGLV--GESTPSRLSP-SSTETTTLPGSPT 2989

Query: 701  ----ANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVP 756
                +     F  +   P     PA T S G S     S +   +T  T  P ST     
Sbjct: 2990 TPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGL 3049

Query: 757  AHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAATSSGFGATTQ 816
            +  PT    + G    +      TAS+ G  +++  +  G T        T +       
Sbjct: 3050 SQEPTASHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEAS 3109

Query: 817  TASSGSSSSVFGSTTPSPFTFGG-----------------SAAPAGSGSFGINVAT---- 855
            T +  S+ S+  + TP+  T  G                 + +P G+ +  + V+T    
Sbjct: 3110 TPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHS 3169

Query: 856  -PGSSATT----GAFSFGAGQSGSTATSTPFTGGLGQNALGTTGQSTPFAFNVGSTTESK 910
             P S+ TT     + + G  +  +T  S+P   G    AL  T  +T  +  VG  T S 
Sbjct: 3170 RPSSTPTTHFSASSTTLGRSEESTTVHSSP---GATGTALFPTRSAT--SVLVGEPTTSP 3224

Query: 911  PVFGGTATPTFGQNTPAPGVGTSGSS 936
               G T T     +T   G+    ++
Sbjct: 3225 ISSGSTETTALPGSTTTAGLSEKSTT 3250



 Score = 98.2 bits (243), Expect = 3e-20
 Identities = 214/940 (22%), Positives = 330/940 (35%), Gaps = 129/940 (13%)

Query: 28   SSTLSSPSSNAPDPCAKETVLSALKEKKKKRTVEEEDQIFLDGQENKRRRHDSSGSGHSA 87
            + T  SP +  P     E+          K T   ++       E     H S+GS H+ 
Sbjct: 346  TDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSSTGSPHTT 405

Query: 88   FEPLVAS---GVPASFVPKPGSLKRGLNSQSSDDHLNKRSRSSSMSSLTGAYTSGIPSSS 144
              P  ++   G P +F   P S          D        +S+   L+  Y S  PSS+
Sbjct: 406  LSPSSSTTHEGEPTTFQSWPSS---------KDTSPAPSGTTSAFVKLSTTYHSS-PSST 455

Query: 145  RNAITSSYSSTRGISQLWKRNGPSSSPFSSP-ASSRSQTPERPAKK--IREEELCHHSSS 201
                 S+ S+T G S+       S+   SSP A++ +  P R A    + E    H S  
Sbjct: 456  PTTHFSASSTTLGHSE------ESTPVHSSPVATATTPPPARSATSGHVEESTAYHRSPG 509

Query: 202  STPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQ 261
            ST      ES       TT     + +S+ +    G         PS             
Sbjct: 510  STQTMHFPESS------TT-----SGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSS 558

Query: 262  LGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTE--TPPTTQPSFTFTLPAAATAS 319
            LG + T    D    +     ++A     DA + +V    + P+     +   P ++ + 
Sbjct: 559  LGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSM 618

Query: 320  PPTSLLAPSTNP-LLESLKKMQTPPSLPPCPESAGAATTEALSPPKTPSLLPPLGLSQSG 378
              T+L   +T P L E      + P  P       + T+  +S   T S   P     + 
Sbjct: 619  ETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTA 678

Query: 379  PPGLLPSPSFDSK---------PPTTLL--GLIPAPSMVPATDTKAPPTLQAETATKPQA 427
             PG    P    +         P  T L  G   A S+ P   T        ET   P  
Sbjct: 679  FPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDN 738

Query: 428  TSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPPGPSVTA 487
            T+A S   + S    +   SP +  +PA S+        F + P S+   P PP      
Sbjct: 739  TTA-SGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPP------ 791

Query: 488  TAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLA 547
                        +TT+   +P  +S G P+S+P      + TT+     +TT     G  
Sbjct: 792  ------------TTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGST 839

Query: 548  SATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQASAA 607
                     T   P +D+ S    G G  S +S S +T T ++  ++   L   P +  +
Sbjct: 840  Q--------TMHFPESDTTS----GRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHS 887

Query: 608  SFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPAT 667
            S                 P +T  T F  S  T+    +  S A  S   +T     PA 
Sbjct: 888  S-----------------PGSTATTHFPDSSTTS--GRSEESTASHSSQDATGTIVLPAR 928

Query: 668  SSQPTLTFSNTSTPTFNIPFGSSAKSPLP---SYPGANPQ-PAFGAAEGQPPGAAKPALT 723
            S+   L   +T++P   I  GS   + LP   + PG + +   F ++   P     PA T
Sbjct: 929  STTSVLLGESTTSP---ISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPAST 985

Query: 724  PSFGSSFTFGNSAAPAPATAPTPAPASTIKIVPAHVPTPIQPTFGGATHSAFGLKATASA 783
             S G S     S +   +T  T  P ST         TP        +HS+ G   T   
Sbjct: 986  TSSGVSEESTTSRSRPGSTHTTAFPDST--------TTPGLSRHSTTSHSSPGSTDTTLL 1037

Query: 784  FGAPASSQPAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAP 843
              +  +S P+   +T+  S G+  ++    +T   S G  S+ F S   S  T   +  P
Sbjct: 1038 PASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHT---TLFP 1094

Query: 844  AGSGSFGINVATPGSSATTGAFSFGAGQSGSTATSTPFTGGLGQNALGTTGQSTPFAFNV 903
              + S GI  A+    ++TG+       + ST+              G  G+ST F  + 
Sbjct: 1095 DSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSP-------------GLQGESTAFQTHP 1141

Query: 904  GSTTESKPVFGGTATPTFGQNTPAPGVGTSGSSLSFGASS 943
             S T + P    TAT    ++T       S  +  F ASS
Sbjct: 1142 AS-THTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASS 1180



 Score = 97.8 bits (242), Expect = 4e-20
 Identities = 219/919 (23%), Positives = 334/919 (36%), Gaps = 97/919 (10%)

Query: 97   PASFVPKPGSLKRGLNSQSSDDHLNKRSRSSSMSSLTGAYTSGIPSSSRNAITSSYSSTR 156
            PAS      S K  +   S D      S + S +S  G  T+   S     IT+   ST 
Sbjct: 3817 PASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTT 3876

Query: 157  --GISQLWKRNGPSSSPFSSPASSRSQTPERPAKKIREEELCHHSSSSTPLAADKESQGE 214
              G+S+       S++ +SSP   RS T       +    +   S++S        S   
Sbjct: 3877 TPGLSEA------STTFYSSP---RSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVS 3927

Query: 215  KAADTTPRKKQNSNS--QSTPGSSGQRKRKVQLLPSRRGEQLTL--PPPPQLGYSITAED 270
             A+ TTP   + S +   S+PGS+           S R E+ T     P     ++  ED
Sbjct: 3928 PASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTED 3987

Query: 271  LDLE-----------KKASLQWFNQALEDKSDAASNSVTETPPTTQPSFTFTLPAAATAS 319
                             AS Q    A    +D    S T  P ++  + T   PA +T S
Sbjct: 3988 STTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTT-FPSSSGSTGTKLSPARSTTS 4046

Query: 320  PPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALSPPKTPSLLPPLGLSQSG- 378
                   PS   L  S  +  T P  P  P  +  +TT   SP    + L P   + SG 
Sbjct: 4047 GLVGESTPSR--LSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGV 4104

Query: 379  ---------PPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKA---PPTLQAETATKPQ 426
                      PG   + +F     T+ L   P  S      T+A   P +  A +  +  
Sbjct: 4105 SEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQS 4164

Query: 427  ATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPPGPSVT 486
             T   SP   ++ L      +     A   + +S         P  S   G      +  
Sbjct: 4165 TTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQEESTTFQ 4224

Query: 487  ATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTT---APLF 543
            +   SS + P+  STTA   +   +    P+S P        TT   +  +TT   +P  
Sbjct: 4225 SWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGA 4284

Query: 544  TGLAS-ATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAP 602
            TG A   T +   +    P+T   S      G    ++   STTT+  +  S  F + +P
Sbjct: 4285 TGTALFPTRSATSVLVGEPTTSPISS-----GSTETTALPGSTTTAGLSEKSTTF-YSSP 4338

Query: 603  QASAASFTPAM----GSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGS 658
            ++   + +PA     G   +     + P +   T F  S  T +P  +  S A  S  GS
Sbjct: 4339 RSPDTTLSPASTTSSGVSEESTTSHSRPGSMHTTAFPSS--TTMPGVSQESTASHSSPGS 4396

Query: 659  TLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGAN----PQPAFGAAEGQP 714
            T  T +P +++  +L   +T   TF+   GS+  + LP    A+          ++ G P
Sbjct: 4397 TDTTLSPGSTTASSLGPEST---TFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSP 4453

Query: 715  PGAAKPA-LTPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVPAHVPTPIQPTFGGATH- 772
                 PA  T   G S TF  S   +  T P P P +T   V     +   P+    TH 
Sbjct: 4454 HTTLSPAGSTTRQGESTTF-QSWPNSKDTTPAP-PTTTSAFVELSTTSHGSPSSTPTTHF 4511

Query: 773  SAFGLKATASAFGAPASSQPAFGGSTAVFSFGAATSSGF--GATTQTASSGSSSSVF--- 827
            SA       S       S P    +T   S   +T+SG    +TT  +S GS+ ++    
Sbjct: 4512 SASSTTLGRSEESTTVHSSPVATATTP--SPARSTTSGLVEESTTYHSSPGSTQTMHFPE 4569

Query: 828  ----------GSTTPSPFTFGGSAAPAGSGSFGINV----ATPGSSATTGAFSFGAGQSG 873
                       +T+ S  T   S+AP+ + +         ++PGS+ATT  F   +  SG
Sbjct: 4570 SNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTH-FPDSSTTSG 4628

Query: 874  STATSTPFTGGLGQNALGTT---GQSTPFAFNVGSTTESKPVFGGTATPTFGQNTPAPGV 930
             +  ST       Q+A GT     +ST     +G +T S    G   T     +T  PG+
Sbjct: 4629 RSEEST--ASHSSQDATGTIVLPARSTTSVL-LGESTTSPISSGSMETTALPGSTTTPGL 4685

Query: 931  GTSGSSLSFGASSAPAQGF 949
                ++     SS P   F
Sbjct: 4686 SEKSTTFHSSPSSTPTTHF 4704



 Score = 97.4 bits (241), Expect = 6e-20
 Identities = 206/930 (22%), Positives = 325/930 (34%), Gaps = 131/930 (14%)

Query: 103  KPGSLKRGLNSQSSDDHLNKRSRSSSMSSLTGAYTSGIPSSSRNAITSSYSSTRGISQLW 162
            +P +   G  S     H++ RS +S +   +  Y S  P S++        +T G     
Sbjct: 799  EPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSS-PGSTQTMHFPESDTTSG----- 852

Query: 163  KRNGPSSSPFSSPASSRSQTPERPAKKIREEELCHHSS-----------SSTPLAADKES 211
             R   S++  SS   + S  P   +  + EE   +HSS           SST     +ES
Sbjct: 853  -RGEESTTSHSSTTHTISSAPSTTSALV-EEPTSYHSSPGSTATTHFPDSSTTSGRSEES 910

Query: 212  QGEKAAD----------------------TTPRKKQNSNSQSTPGSS---GQRKRKVQLL 246
                ++                       T+P    +  + + PGS+   G  +R     
Sbjct: 911  TASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFH 970

Query: 247  PSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETPPTTQP 306
             S R    TL P       ++ E      +        A  D +     S   T   + P
Sbjct: 971  SSPRSPATTLSPASTTSSGVSEESTTSRSRPG-STHTTAFPDSTTTPGLSRHSTTSHSSP 1029

Query: 307  SFTFT--LPAAATASPPT--------------SLLAPSTNPLL----ESLKKMQTPPS-- 344
              T T  LPA+ T S P+              + L+P +   L    ES      P S  
Sbjct: 1030 GSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTH 1089

Query: 345  ---LPPCPESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLL-PSPSFDSKPPTTLLGLI 400
                P    S+G           T S    L  + S  PGL   S +F + P +T     
Sbjct: 1090 TTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPAST--HTT 1147

Query: 401  PAPSMVPATDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSAS 460
            P+P   P+T T   P  ++ T  +   ++  +  P  S   G    S    ++P AS  +
Sbjct: 1148 PSP---PSTATA--PVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTT 1202

Query: 461  PMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVP 520
            P      T+           PG +   T P S++ P   S  + TF   +SS   P +  
Sbjct: 1203 PSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGL-SEASTTF---YSSPRSPTTTL 1258

Query: 521  LPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSS 580
             PA     T+      +TT+    G  S  S V+P ++ +P     S   +     S  +
Sbjct: 1259 SPA---SMTSLGVGEESTTSRSQPG--STHSTVSPASTTTPGLSEESTTVYSSSRGSTET 1313

Query: 581  SSVSTTTSTATAASQPFLFGAPQASAAS--FTPAMGSIFQFGKPPALPTTTTVTTFSQSL 638
            +    +T+T+    +P  F +  AS  +  FT    +     +  A P +   T     L
Sbjct: 1314 TVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPAST--QTGL 1371

Query: 639  PTAVPTAT--SSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLP 696
            P  + TA     S    S  GST    +PA S+   L     STP+   P  S+  + LP
Sbjct: 1372 PATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLV--GESTPSRLSP-SSTETTTLP 1428

Query: 697  SYPG----ANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPASTI 752
              P     +     F  +   P     PA T S G S     S +   +T  T  P ST 
Sbjct: 1429 GSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTT 1488

Query: 753  KIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAATSSGFG 812
                +  PT    + G    +      TAS+ G  +++  +  G T        T +   
Sbjct: 1489 TSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGL 1548

Query: 813  ATTQTASSGSSSSVFGSTTPSPFTFGG-----------------SAAPAGSGSFGINVAT 855
                T +  S+ S+  + TP+  T  G                 + +P G+ +  + V+T
Sbjct: 1549 VEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVST 1608

Query: 856  -----PGSSATT----GAFSFGAGQSGSTATSTPFTGGLGQNALGTTGQSTPFAFNVGST 906
                 P S+ TT     + + G  +  +T  S+P   G    AL  T  +T  +  VG  
Sbjct: 1609 TYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSP---GATGTALFPTRSAT--SVLVGEP 1663

Query: 907  TESKPVFGGTATPTFGQNTPAPGVGTSGSS 936
            T S    G T T     +T   G+    ++
Sbjct: 1664 TTSPISSGSTETTALPGSTTTAGLSEKSTT 1693



 Score = 95.9 bits (237), Expect = 2e-19
 Identities = 222/1026 (21%), Positives = 350/1026 (34%), Gaps = 199/1026 (19%)

Query: 78   HDSSGSGHSAFEPLVASGVPASFVPKPGSLKRGLNSQSSDDHLNKRSRSSSMSSLTGAYT 137
            H S+GS H+   P              GS  R   S +     N +  + +  + T A+ 
Sbjct: 3364 HSSTGSPHTTLSPA-------------GSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFV 3410

Query: 138  S------GIPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSP-ASSRSQTPERPAKK- 189
                   G PSS+     S+ S+T G      R+  S++  SSP A++ + +P R     
Sbjct: 3411 ELSTTSHGSPSSTPTTHFSASSTTLG------RSEESTTVHSSPVATATTPSPARSTTSG 3464

Query: 190  -IREEELCHHSSSSTPLAADKESQ---GEKAADTTPRKKQNSNSQSTPGSSGQRKRKVQL 245
             + E    H S  ST      ES    G     TT          S P ++     +   
Sbjct: 3465 LVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTS 3524

Query: 246  LPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETPPTTQ 305
              S  G   T   P     S  +E+            + A     DA    V     TT 
Sbjct: 3525 YHSSPGSTATTHFPDSSTTSGRSEE------------STASHSSQDATGTIVLPARSTTS 3572

Query: 306  PSF--TFTLPAAATASPPTSLLAPSTNP-LLESLKKMQTPPSLPPCPESAGAATTEALSP 362
                 + T P ++ +   T+L   +T P L E      + P  P    S  + T+  +S 
Sbjct: 3573 VLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSE 3632

Query: 363  PKTPSLLPPLGLSQSGPPGLLPSPSFD-------SKPPTTLLGLIPAPSMVPATDTKAPP 415
              T S   P     +  P    +P          S P +T   L+PA +    +  ++  
Sbjct: 3633 ESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTT 3692

Query: 416  TLQA----ETATKPQATSA-----------PSPAPKQSFLFGTQNTSP----------SS 450
            +  +    +TA  P +T+A            SP    + LF    TS           SS
Sbjct: 3693 SHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSS 3752

Query: 451  PAAPA-----ASSASPMFKPIFTAPPKSEKEGPTPPGPSVTATAP---------SSSSLP 496
              +P      ASS SP  +   TA         T P P  TATAP         S  S P
Sbjct: 3753 TGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTP 3812

Query: 497  TTT--------------------------------STTAPTFQPVFSSMGP--------P 516
            TT                                 STT+   +   S + P        P
Sbjct: 3813 TTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLP 3872

Query: 517  ASVPLPA------PFFKQTTTPAT--APTTTAPLFTGLASATS---------AVAPITSA 559
             S   P        F+    +P T  +P +   L  G  S TS          V+P ++ 
Sbjct: 3873 GSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTT 3932

Query: 560  SPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQF 619
            +P     S   +     S  ++    +T+T+    +P  F                    
Sbjct: 3933 TPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTF-------------------- 3972

Query: 620  GKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTS 679
                + P +T  T F++   T+  T  S++   F G  ++  T  PAT +   L   +T+
Sbjct: 3973 ---HSRPASTHTTLFTEDSTTSGLTEESTA---FPGSPASTQTGLPATLTTADLGEESTT 4026

Query: 680  TPTFNIPFG---SSAKSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSA 736
             P+ +   G   S A+S      G +       +  +         TPS     T   ++
Sbjct: 4027 FPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTS 4086

Query: 737  APAPATAPTPAPASTIKIVPAHVPTPIQPTFGGATH-SAFGLKATASAFG-APASSQPAF 794
              +P    +PA  ++  +      +  QP   G+TH +AF    T S     P +S  + 
Sbjct: 4087 PRSPDATLSPATTTSSGVSEESSTSHSQP---GSTHTTAFPDSTTTSGLSQEPTTSHSSQ 4143

Query: 795  GGSTAVFSFGAATSSGFG--ATTQTASSGSSSSVF--GSTTPSPFTFGGSAAPAGSGSFG 850
            G + A  S G+ T+S  G  +TT  +S G + +      T  S      +   + +GS  
Sbjct: 4144 GSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLH 4203

Query: 851  INVATPGSSATTG----AFSFGAGQSGSTATSTPFTGGLGQNALGTTGQSTPFAFNVGST 906
              + TP SS +TG    + +F +  S S  T +P +       + TT  S P +      
Sbjct: 4204 TTL-TPASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHF 4262

Query: 907  TESKPVFGGTATPTFGQNTPAPGVGTSGSSLSFGASSAPA--QGFVGVGPFGSAAPSFSI 964
            + S    G +   T   ++P    G +G++L F   SA +   G     P  S +   + 
Sbjct: 4263 SASSTTLGRSEESTTVHSSP----GATGTAL-FPTRSATSVLVGEPTTSPISSGSTETTA 4317

Query: 965  GAGSKT 970
              GS T
Sbjct: 4318 LPGSTT 4323



 Score = 95.5 bits (236), Expect = 2e-19
 Identities = 216/987 (21%), Positives = 358/987 (36%), Gaps = 129/987 (13%)

Query: 29   STLSSPSSNAPDPCAKETVLSALKEKKKKRTVEEEDQIFLDGQENKRRRHDSSGSGHSAF 88
            ST+S  S+  P    + T + +      + TV           E     H    S H+  
Sbjct: 1284 STVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTL 1343

Query: 89   --EPLVASGVP---ASFVPKPGSLKRGLNSQSSDDHLNKRSRS-SSMSSLTGAYTSGIPS 142
              E    SG+     +F   P S + GL +  +   L + S +  S S  TG   S   S
Sbjct: 1344 FTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARS 1403

Query: 143  SSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRSQT----PERP----------AK 188
            ++   +  S  S    S       P S P +   S +S T    P  P          + 
Sbjct: 1404 TTSGLVGESTPSRLSPSSTETTTLPGS-PTTPSLSEKSTTFYTSPRSPDATLSPATTTSS 1462

Query: 189  KIREEELCHHS---SSSTPLAADKESQGEKAADTTPRKKQNSNSQST--PGSS-----GQ 238
             + EE    HS   S+ T    D  +  + + + T       ++++T  PGS+     GQ
Sbjct: 1463 GVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQ 1522

Query: 239  RKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVT 298
            +       P    E   LP        + A         SL          S +A     
Sbjct: 1523 QSTTFHSSPGDT-ETTLLPDDTITSGLVEASTPTHSSTGSLH--TTLTPASSTSAGLQEE 1579

Query: 299  ETPPTTQPSFTFTLPAAATASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTE 358
             T   + PS + T P     SPP +  AP     +E      + PS  P    + ++TT 
Sbjct: 1580 STTFQSWPSSSDTTP-----SPPGTTAAP-----VEVSTTYHSRPSSTPTTHFSASSTTL 1629

Query: 359  ALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQ 418
              S   T         +    PG   +  F ++  T++L   P  S + +  T       
Sbjct: 1630 GRSEEST---------TVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGST------- 1673

Query: 419  AETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGP 478
             ET   P +T+    + K +  + +   SP +  +PA++++S + +   T+  +      
Sbjct: 1674 -ETTALPGSTTTAGLSEKSTTFYSSPR-SPDTTLSPASTTSSGVSEESTTSHSRPGSTHT 1731

Query: 479  TP-PG----PSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPA 533
            T  PG    P V+  + +S S P +T TT        SS+GP ++           ++P 
Sbjct: 1732 TAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTT--------FHSSPG 1783

Query: 534  TAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAA 593
            +  TT  P  T  +    A  P+ S++ S  +   PA      S +    STT  +  ++
Sbjct: 1784 STETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPA-----GSTTRQGESTTFQSWPSS 1838

Query: 594  SQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTT------TTV-----TTFSQSLPTAV 642
                   AP  + ++F     S    G P + PTT      TT+     +T   S P A 
Sbjct: 1839 KD--TMPAPPTTTSAFVEL--STTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVAT 1894

Query: 643  PTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGAN 702
             T  S + +  SG          +  S  T+ F  +ST +       ++ S       + 
Sbjct: 1895 ATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSP 1954

Query: 703  PQPAFGAAEGQPPGAAKPALTPS--FGSSFTFGNSAAPAPATAPTPAPASTIKIVPAHVP 760
            P       E      + P  T +  F  S T    +  + A+  +     TI ++PA   
Sbjct: 1955 PSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTI-VLPARST 2013

Query: 761  TPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAATSSGFGATTQTASS 820
            T +    G +T S     +  +     +++ P     +  F     + +   +   T SS
Sbjct: 2014 TSV--LLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSS 2071

Query: 821  G------SSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATT----GAFSFGAG 870
            G      +S S  GST  + F    +  P  S     + ++PGS+ TT       + G  
Sbjct: 2072 GVSEESTTSHSRPGSTHTTAFP-DSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPS 2130

Query: 871  QSGSTATSTPFTGGLGQNALGTTGQSTPFAFNVGSTT-ESKPVFGGTATPTFGQNTPAPG 929
            Q  +T+ S+P   G    AL + G +T  +F   STT  S P  G T T  F  +T + G
Sbjct: 2131 QESTTSHSSP---GSTDTAL-SPGSTTALSFGQESTTFHSSP--GSTHTTLFPDSTTSSG 2184

Query: 930  V-----------GTSGSSLSFGASSAP 945
            +           G+  ++LS  +S++P
Sbjct: 2185 IVEASTRVHSSTGSPRTTLSPASSTSP 2211



 Score = 95.1 bits (235), Expect = 3e-19
 Identities = 221/1000 (22%), Positives = 363/1000 (36%), Gaps = 149/1000 (14%)

Query: 33   SPSSNAPDPCAKETVLSALKEKKKKRTVEEEDQIFLDGQENKRRRHDSSGSGHSAFEPLV 92
            SP++      ++E+  S  +      T   +     D  +     H S GS  +   P  
Sbjct: 1455 SPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSP-- 1512

Query: 93   ASGVPASFVPKPGSLKRGLNSQSSDDHLNKRSRSSSMSSLTGAYTSGIPS--SSRNAITS 150
                 AS +   G      +S   D         +  S L  A T    S  S    +T 
Sbjct: 1513 -GSTTASSL---GQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTP 1568

Query: 151  SYSSTRGISQLWKRNGPSSSPFSSPASSRSQTPERP---AKKIREEELCHHSSSSTPLAA 207
            + S++ G+ +        S+ F S  SS   TP  P   A  +      H   SSTP   
Sbjct: 1569 ASSTSAGLQE-------ESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTH 1621

Query: 208  DKESQGEKAADTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSIT 267
               S     + T  R ++++   S+PG++G       L P+R    + +  P     S  
Sbjct: 1622 FSAS-----STTLGRSEESTTVHSSPGATG-----TALFPTRSATSVLVGEPTTSPISSG 1671

Query: 268  AEDLDLEKKASLQWFNQALEDKSDAASNSVTETPPTTQP-SFTFTLPAAATASPPTSLLA 326
            + +              AL   +  A  S   T   + P S   TL  A+T S   S  +
Sbjct: 1672 STE------------TTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEES 1719

Query: 327  PSTNPLLESLKKMQTPPSLPPCPESAGAATTEALSPPKTPSLLPPLGLSQS--GPPGLLP 384
             +++    S      P S    P  +  +T    SP  T + L P   + S  GP     
Sbjct: 1720 TTSHSRPGSTHTTAFPGSTT-MPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPE---- 1774

Query: 385  SPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQ 444
            S +F S P +T   L+P        +T A   L+A T                     + 
Sbjct: 1775 STTFHSSPGSTETTLLP-------DNTTASGLLEASTPVH------------------SS 1809

Query: 445  NTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAP 504
              SP +  +PA S+        F + P S+   P PP  +      S++S  + +ST   
Sbjct: 1810 TGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTT 1869

Query: 505  TFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSA---SP 561
             F    +++G            +++TT  ++P  TA   +   S TS +   ++A   SP
Sbjct: 1870 HFSASSTTLGRS----------EESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSP 1919

Query: 562  -STDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFG 620
             ST +   P           S  S +++T T +S P    A      S+  + GS     
Sbjct: 1920 GSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTH 1979

Query: 621  KPPALPTT-----TTVTTFSQSLPTAVPTATSSSAADFSG--------FGSTLATSAPAT 667
             P +  T+     +T +  SQ     +     S+ +   G         GS   T+ P +
Sbjct: 1980 FPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGS 2039

Query: 668  SSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQP----PGA----AK 719
            ++ P L+  +T+       F SS +SP  +   A+   +  + E       PG+    A 
Sbjct: 2040 TTTPGLSEKSTT-------FHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAF 2092

Query: 720  PALTPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVPAHVPTPIQPTFGGATHSAFGLKA 779
            P  T + G S     S +   +T  T  PAST    P+   T    + G    +      
Sbjct: 2093 PDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGST 2152

Query: 780  TASAFGAPASSQPAFGGSTAVFSFGAAT--------------SSGFGATTQTASSGSSSS 825
            TA +FG  +++  +  GST    F  +T              S+G   TT + +S +S  
Sbjct: 2153 TALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPG 2212

Query: 826  VFGSTT---PSPFTFGGSAAPAGSGSFGINVAT-----PGSSATTGAFSFGAGQSGSTAT 877
            + G +T     P +   + +P  + +  +  +T     PGS+ TT  F   +  SG +  
Sbjct: 2213 LQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTT-HFPASSTTSGHSEK 2271

Query: 878  STPFTGGLGQNALGTTGQST-PFAFNVGSTTESKPVFGGTATPTFGQNTPAPGVGTSGSS 936
            ST F      +A GTT  S        G +T S+   G T   T   +T  PG+ +  S+
Sbjct: 2272 STIFHS--SPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGL-SEAST 2328

Query: 937  LSFGASSAPAQGFVGVGPFGSAAPSFSIGAGSKTPGARQR 976
              + +  +P           S A   S+G G ++  +R +
Sbjct: 2329 TFYSSPRSPTTTL-------SPASMTSLGVGEESTTSRSQ 2361



 Score = 92.4 bits (228), Expect = 2e-18
 Identities = 230/1009 (22%), Positives = 372/1009 (36%), Gaps = 149/1009 (14%)

Query: 80   SSGSGHSAFEP-------LVASGVPASFVPK-------PGS-LKRGLNSQSSDDHLNKRS 124
            SSGS  +   P       LV    P+   P        PGS     L+ +S+  + + RS
Sbjct: 2947 SSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRS 3006

Query: 125  RSSSMSSLTGAYTSGI----------PSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSS 174
              +++S  T   +SG+          P S+        ++T G+SQ      P++S  S 
Sbjct: 3007 PDATLSPATTT-SSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQ-----EPTASHSSQ 3060

Query: 175  PASSRSQTP-ERPAKKIREEELCHHSS----SSTPLAADKESQGEKAADTTPRKKQNS-N 228
             ++  + +P    A  + ++    HSS     +T L  D  + G   A T       S +
Sbjct: 3061 GSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLH 3120

Query: 229  SQSTPGSSGQR--KRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEK----------- 275
            +  TP SS     + +     S      T P PP      TA  +++             
Sbjct: 3121 TTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPP----GTTAAPVEVSTTYHSRPSSTPT 3176

Query: 276  ---KASLQWFNQALEDKSDAASNSVTETPPTTQPSFTFTLPAAATASP------PTSLLA 326
                AS     ++ E  +  +S   T T      S T  L    T SP       T+ L 
Sbjct: 3177 THFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALP 3236

Query: 327  PSTNP--LLESLKKMQTPPSLPPCPESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLP 384
             ST    L E      + P  P    S  + T+  +S   T S   P     +  PG   
Sbjct: 3237 GSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTT 3296

Query: 385  SPSFD-------SKPPTTLLGLIP----APSMVPATDTKAPPTLQAETATKPQATSAPSP 433
             P          S P +T   L P    A S+ P + T        ET   P  T+A S 
Sbjct: 3297 MPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPGSTETTLLPDNTTA-SG 3355

Query: 434  APKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSS 493
              + S    +   SP +  +PA S+        F + P S+   P PP  +      S++
Sbjct: 3356 LLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTT 3415

Query: 494  SLPTTTSTTAPTFQPVFSSMG-PPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSA 552
            S  + +ST    F    +++G    S  + +      TTP+ A +TT+ L     +  S+
Sbjct: 3416 SHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSS 3475

Query: 553  VAPI-TSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTP 611
                 T   P +D+ S      G    S++S S+TT T ++A  P    A      S+  
Sbjct: 3476 PGSTQTMHFPESDTTS------GRGEESTTSHSSTTHTISSA--PSTTSALVEEPTSYHS 3527

Query: 612  AMGSIFQFGKPPALPTT-----TTVTTFSQSLPTAVPTATSSSAADFSG--------FGS 658
            + GS      P +  T+     +T +  SQ     +     S+ +   G         GS
Sbjct: 3528 SPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGS 3587

Query: 659  TLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQP---- 714
               T+ P +++ P L+  +T+       F SS +SP  +   A+   +  + E       
Sbjct: 3588 METTALPGSTTTPGLSEKSTT-------FHSSPRSPATTLSPASTTSSGVSEESTTSHSR 3640

Query: 715  PGA----AKPALTPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVPAHVPTPIQPTFGGA 770
            PG+    A P  T + G S     S +   +T  T  PAST     +   T    + G  
Sbjct: 3641 PGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTSHSSSGST 3700

Query: 771  THSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAAT--------------SSGFGATTQ 816
              +      TA +FG  +++  +  GST    F  +T              S+G   TT 
Sbjct: 3701 DTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTL 3760

Query: 817  TASSGSSSSVFGSTT---PSPFTFGGSAAPAGSGSFGINVAT-----PGSSATTGAFSFG 868
            + +S +S  + G +T     P +   + +P  + +  +  +T     PGS+ TT  F   
Sbjct: 3761 SPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTT-HFPAS 3819

Query: 869  AGQSGSTATSTPFTGGLGQNALGTTGQST-PFAFNVGSTTESKPVFGGTATPTFGQNTPA 927
            +  SG +  ST F      +A GTT  S        G +T S+   G T   T   +T  
Sbjct: 3820 STTSGHSEKSTIFHS--SPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTT 3877

Query: 928  PGVGTSGSSLSFGASSAPAQGFVGVGPFGSAAPSFSIGAGSKTPGARQR 976
            PG+ +  S+  + +  +P           S A   S+G G ++  +R +
Sbjct: 3878 PGL-SEASTTFYSSPRSPTTTL-------SPASMTSLGVGEESTTSRSQ 3918



 Score = 91.7 bits (226), Expect = 3e-18
 Identities = 214/980 (21%), Positives = 353/980 (36%), Gaps = 115/980 (11%)

Query: 29   STLSSPSSNAPDPCAKETVLSALKEKKKKRTVEEEDQIFLDGQENKRRRHDSSGSGHSAF 88
            ST+S  S+  P    + T + +      + TV           E     H    S H+  
Sbjct: 2841 STVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHSRPASTHTTL 2900

Query: 89   --EPLVASGVP---ASFVPKPGSLKRGLNSQSSDDHLNKRSRS-SSMSSLTGAYTSGIPS 142
              E    SG+     +F   P S + GL +  +   L + S +  S S  TG   S   S
Sbjct: 2901 FTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARS 2960

Query: 143  SSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRSQT----PERP----------AK 188
            ++   +  S  S    S       P S P +   S +S T    P  P          + 
Sbjct: 2961 TTSGLVGESTPSRLSPSSTETTTLPGS-PTTPSLSEKSTTFYTSPRSPDATLSPATTTSS 3019

Query: 189  KIREEELCHHS---SSSTPLAADKESQGEKAADTTPRKKQNSNSQST--PGSS-----GQ 238
             + EE    HS   S+ T    D  +    + + T       ++++T  PGS+     GQ
Sbjct: 3020 GVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQ 3079

Query: 239  RKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVT 298
            +       P    E   LP        + A         SL          S +A     
Sbjct: 3080 QSTTFHSSPGDT-ETTLLPDDTITSGLVEASTPTHSSTGSLH--TTLTPASSTSAGLQEE 3136

Query: 299  ETPPTTQPSFTFTLPAAATASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTE 358
             T   + PS + T P     SPP +  AP     +E      + PS  P    + ++TT 
Sbjct: 3137 STTFQSWPSSSDTTP-----SPPGTTAAP-----VEVSTTYHSRPSSTPTTHFSASSTTL 3186

Query: 359  ALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQ 418
              S   T         +    PG   +  F ++  T++L   P  S + +  T       
Sbjct: 3187 GRSEEST---------TVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGST------- 3230

Query: 419  AETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGP 478
             ET   P +T+    + K +  + +   SP +  +PA++++S + +   T+  +      
Sbjct: 3231 -ETTALPGSTTTAGLSEKSTTFYSSPR-SPDTTLSPASTTSSGVSEESTTSHSRPGSTHT 3288

Query: 479  TP-PG----PSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPA 533
            T  PG    P V+  + +S S P +T TT        SS+GP ++     P   +TT   
Sbjct: 3289 TAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPGSTETTLLP 3348

Query: 534  TAPTTTAPLFTGLASATSAVAPITSASP---STDSASKPAFGFGINSVSSSSVSTTTSTA 590
               T +  L       +S  +P T+ SP   +T       F    NS  ++    TT++A
Sbjct: 3349 DNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSA 3408

Query: 591  TAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTA--TSS 648
                     G+P ++  +   A  +     +      ++ V T +   P    T+     
Sbjct: 3409 FVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEE 3468

Query: 649  SAADFSGFGSTLATSAP---ATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQP 705
            S    S  GST     P    TS +   + ++ S+ T  I    S  S L   P +    
Sbjct: 3469 STTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSS 3528

Query: 706  AFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVPAHVPTPI-- 763
                A    P +   + T       T  +S+  A  T   PA ++T  ++     +PI  
Sbjct: 3529 PGSTATTHFPDS---STTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISS 3585

Query: 764  ---QPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAATSSGFG--ATTQTA 818
               + T    + +  GL   ++ F +   S PA        S  + TSSG    +TT  +
Sbjct: 3586 GSMETTALPGSTTTPGLSEKSTTFHSSPRS-PA-----TTLSPASTTSSGVSEESTTSHS 3639

Query: 819  SSGSS-SSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATTGAFSFGAGQSGSTAT 877
              GS+ ++ F  +T +P     S     S         P S+ T+G        S   +T
Sbjct: 3640 RPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSG--------SSQEST 3691

Query: 878  STPFTGGLGQNALGTTGQSTPFAFNVGSTT-ESKPVFGGTATPTFGQNTPAPGV------ 930
            ++  + G    AL + G +T  +F   STT  S P  G T T  F  +T + G+      
Sbjct: 3692 TSHSSSGSTDTAL-SPGSTTALSFGQESTTFHSSP--GSTHTTLFPDSTTSSGIVEASTR 3748

Query: 931  -----GTSGSSLSFGASSAP 945
                 G+  ++LS  +S++P
Sbjct: 3749 VHSSTGSPRTTLSPASSTSP 3768



 Score = 87.4 bits (215), Expect = 6e-17
 Identities = 177/826 (21%), Positives = 294/826 (35%), Gaps = 132/826 (15%)

Query: 30   TLSSPSSNAPDPCAKETVLSALKEKKKKRTVEEEDQIFLDGQENKRRRHDSSGSGHSAFE 89
            T  SP+S      ++E+  S  +      T            +     H S GS  +   
Sbjct: 4343 TTLSPASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSSPGSTDTTLS 4402

Query: 90   PLVASGVPASFVPKPGSLKRGLNSQSSDDHLNKRSRSSSMSSLTGAYTSGIPSSSRNAIT 149
            P   S   +S  P+  +      S  +    +  + S  + + T  ++S    S    ++
Sbjct: 4403 P--GSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSS--TGSPHTTLS 4458

Query: 150  SSYSSTRGISQLWKRNGPSSSPFSSPASSRSQTPERPAKKIREEELC------------- 196
             + S+TR            S+ F S  +S+  TP  P       EL              
Sbjct: 4459 PAGSTTRQ---------GESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTT 4509

Query: 197  HHSSSSTPLAADKES----QGEKAADTTPRKKQNSNS---------QSTPGSSGQRKRKV 243
            H S+SST L   +ES        A  TTP   +++ S          S+PGS+       
Sbjct: 4510 HFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPE 4569

Query: 244  QLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETPPT 303
                S RGE+ T        +S T   +      +     +     S   S + T  P +
Sbjct: 4570 SNTTSGRGEESTT------SHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDS 4623

Query: 304  TQPSFTFTLPAAATASPPTS--LLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALS 361
            +  S       A+ +S   +  ++ P+ +     L +  T P       S+G+  T AL 
Sbjct: 4624 STTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPI------SSGSMETTAL- 4676

Query: 362  PPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTL---- 417
                              PG   +P    K  T       +PS  P T   A  T     
Sbjct: 4677 ------------------PGSTTTPGLSEKSTT----FHSSPSSTPTTHFSASSTTLGRS 4714

Query: 418  -QAETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKE 476
             ++ T       +A +P+P +S   G    S +  ++P  S+ +  F    TA  +SE+ 
Sbjct: 4715 EESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPG-STQTMHFPESSTASGRSEES 4773

Query: 477  GPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAP 536
                   S ++T  + SS P+TTS          SS G  A+   P    + +TT   + 
Sbjct: 4774 RT-----SHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFP----ESSTTSGRSE 4824

Query: 537  TTTAPLFTGLASATSAVAPITSA-SPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQ 595
             +TA   +  +  T+ + P+ +  + S   A    F     S+ ++  ST T+   +A  
Sbjct: 4825 ESTA---SHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTATTPGLSAKS 4881

Query: 596  PFLFGAPQASAASFTPA-MGSIFQFGKPPAL------------PTTTTVTTFSQSLPT-- 640
              L+ + ++   + +PA M S    G+P +L            P +TT +  SQ   T  
Sbjct: 4882 TILYSSSRSPDQTLSPASMTSSSISGEPTSLYSQAESTHTTAFPASTTTSGLSQESTTFH 4941

Query: 641  AVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPG 700
            + P +T ++ +  S   S+ A       SQP    S  S  +  +P  S   +   S PG
Sbjct: 4942 SKPGSTETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEESTTFYSSPG 5001

Query: 701  ANPQPAFG--------AAEGQP----PGAAKPAL-----TPSFGSSFTFGNSAAPAPATA 743
            +    AF         + +  P    PG     L     T   G   T  +S++ A  T 
Sbjct: 5002 STETTAFSHSNTMSIHSQQSTPFPDSPGFTHTVLPATLTTTDIGQESTAFHSSSDATGTT 5061

Query: 744  PTPAPASTIKIVPAHV-----PTPIQPTFGGATHSAFGLKATASAF 784
            P PA ++   +V         P+P   T   A+ S  GL   ++ F
Sbjct: 5062 PLPARSTASDLVGEPTTFYISPSPTYTTLFPASSSTSGLTEESTTF 5107



 Score = 86.7 bits (213), Expect = 1e-16
 Identities = 211/955 (22%), Positives = 350/955 (36%), Gaps = 111/955 (11%)

Query: 29   STLSSPSSNAPDPCAKETVLSALKEKKKKRTVEEEDQIFLDGQENKRRRHDSSGSGHSAF 88
            ST+S  S+  P    + T + +      + TV          +E     H    S H+  
Sbjct: 3924 STVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTL 3983

Query: 89   --EPLVASGVP---ASFVPKPGSLKRGLNSQSSDDHLNKRSRS-SSMSSLTGAYTSGIPS 142
              E    SG+     +F   P S + GL +  +   L + S +  S S  TG   S   S
Sbjct: 3984 FTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARS 4043

Query: 143  SSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRSQT----PERP----------AK 188
            ++   +  S  S    S       P S P +   S +S T    P  P          + 
Sbjct: 4044 TTSGLVGESTPSRLSPSSTETTTLPGS-PTTPSLSEKSTTFYTSPRSPDATLSPATTTSS 4102

Query: 189  KIREEELCHHSS-SSTPLAADKES---QGEKAADTTPRKKQNSNSQS-TPGSS-----GQ 238
             + EE    HS   ST   A  +S    G     TT    Q S   + +PGS+     GQ
Sbjct: 4103 GVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTASSLGQ 4162

Query: 239  RKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVT 298
            +       P     + TL P   +   +   +      +S    +  L   S + S  + 
Sbjct: 4163 QSTTFHSSPG--DTETTLLPDDTITSGLV--EASTPTHSSTGSLHTTLTPAS-STSTGLQ 4217

Query: 299  ETPPTTQ--PSFTFTLPAAATASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAAT 356
            E   T Q  PS + T P     SPP++   P     +E      + PS  P    + ++T
Sbjct: 4218 EESTTFQSWPSSSDTTP-----SPPSTTAVP-----VEVSTTYHSRPSSTPTTHFSASST 4267

Query: 357  TEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPT 416
            T   S   T         +    PG   +  F ++  T++L   P  S + +  T     
Sbjct: 4268 TLGRSEEST---------TVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGST----- 4313

Query: 417  LQAETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEK- 475
               ET   P +T+    + K +  + +   SP +  +PA++++S + +   T+  +    
Sbjct: 4314 ---ETTALPGSTTTAGLSEKSTTFYSSPR-SPDTTLSPASTTSSGVSEESTTSHSRPGSM 4369

Query: 476  ------EGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQT 529
                     T PG S  +TA  SS  P +T TT        SS+GP ++    +P   +T
Sbjct: 4370 HTTAFPSSTTMPGVSQESTASHSS--PGSTDTTLSPGSTTASSLGPESTTFHSSPGSTET 4427

Query: 530  TTPATAPTTTAPLFTGLASATSAVAPITSASP---STDSASKPAFGFGINSVSSSSVSTT 586
            T      T +  L       +S  +P T+ SP   +T       F    NS  ++    T
Sbjct: 4428 TLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPT 4487

Query: 587  TSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTA- 645
            T++A         G+P ++  +   A  +     +      ++ V T +   P    T+ 
Sbjct: 4488 TTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSG 4547

Query: 646  -TSSSAADFSGFGSTLATSAP---ATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGA 701
                S    S  GST     P    TS +   + ++ S+ T  I    S  S L   P +
Sbjct: 4548 LVEESTTYHSSPGSTQTMHFPESNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTS 4607

Query: 702  NPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVPAHVPT 761
                    A    P +   + T       T  +S+  A  T   PA ++T  ++     +
Sbjct: 4608 YHSSPGSTATTHFPDS---STTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTS 4664

Query: 762  PI-----QPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAATSSGFGATTQ 816
            PI     + T    + +  GL   ++ F +  SS P     T  FS   A+S+  G  ++
Sbjct: 4665 PISSGSMETTALPGSTTTPGLSEKSTTFHSSPSSTP-----TTHFS---ASSTTLG-RSE 4715

Query: 817  TASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATT--GAFSFGAGQSGS 874
             +++  SS V  +TTPSP     S     S ++    ++PGS+ T      S  +G+S  
Sbjct: 4716 ESTTVHSSPVATATTPSPARSTTSGLVEESTAYH---SSPGSTQTMHFPESSTASGRSEE 4772

Query: 875  TATSTPFTGGLGQNALGTTGQSTPFAFNVGSTTESKPVFGGTATPTFGQNTPAPG 929
            + TS   T     + + +   +T       ++  S P  G  AT  F +++   G
Sbjct: 4773 SRTSHSST----THTISSPPSTTSALVEEPTSYHSSP--GSIATTHFPESSTTSG 4821



 Score = 73.2 bits (178), Expect = 1e-12
 Identities = 133/585 (22%), Positives = 216/585 (36%), Gaps = 103/585 (17%)

Query: 374 LSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAETATKPQATSAPSP 433
           +S SGP G   +  F S   T++   +  P   P T          ET   P +T+    
Sbjct: 226 VSHSGP-GATGTTLFPSHSATSVF--VGEPKTSPITSASM------ETTALPGSTTTAGL 276

Query: 434 APKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPK-------SEKEGPTPPGPSVT 486
           + K +  + +   SP    +PA +++S + +   T+  +       +  +  T PG S  
Sbjct: 277 SEKSTTFYSSPR-SPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQE 335

Query: 487 ATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGL 546
           +TA  S S+P +T TT        SS+GP ++    +P + +TT      TT+  L    
Sbjct: 336 STA--SHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEAST 393

Query: 547 ASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQASA 606
              +S  +P T+ SPS                         S+ T   +P  F +  +S 
Sbjct: 394 PVHSSTGSPHTTLSPS-------------------------SSTTHEGEPTTFQSWPSSK 428

Query: 607 ASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPA 666
            +     G+   F K         ++T   S P++ PT   S                  
Sbjct: 429 DTSPAPSGTTSAFVK---------LSTTYHSSPSSTPTTHFS------------------ 461

Query: 667 TSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSF 726
            +S  TL  S  STP  + P  ++A +P P+    +       A  + PG+ +    P  
Sbjct: 462 -ASSTTLGHSEESTPVHSSPV-ATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPE- 518

Query: 727 GSSFTFGNSAAPAP-ATAPTPAPASTIKIVPAHVPTPIQPTFGGATHSAFGLKATASAFG 785
            SS T G+S   A    + T   +ST     A   T    + G    + F   +T S  G
Sbjct: 519 -SSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTIS--G 575

Query: 786 APASSQPAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAG 845
               S+ +     A+            ATT   +  + S + G +TPSP + G     A 
Sbjct: 576 RSEESKASHSSPDAM------------ATTVLPAGSTPSVLVGDSTPSPISSGSMETTAL 623

Query: 846 SGSFGINVATPGSSATTGAFSFGAGQSGSTATSTPFTGGLGQNALGTTGQSTPFAFNVGS 905
            GS       PG S  +  F + + +S  T          G +   TT  S P       
Sbjct: 624 PGS----TTKPGLSEKSTTF-YSSPRSPDTTHLPASMTSSGVSEESTTSHSRP------G 672

Query: 906 TTESKPVFGGTATPTFGQNTPA--PGVGTSGSSLSFGASSAPAQG 948
           +T +    G T  P   Q + A     G + ++LS G+++A + G
Sbjct: 673 STHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLG 717



 Score = 70.5 bits (171), Expect = 7e-12
 Identities = 187/801 (23%), Positives = 307/801 (38%), Gaps = 168/801 (20%)

Query: 288 DKSDAASNSVTETPPTTQPSFTFTLPAAATASPPTSLLAPSTNPLLESLKKMQTPPSLPP 347
           D S  + +S   T   + P  T T    + ++    +  P T+P+  +   M+T  +LP 
Sbjct: 213 DSSTNSGHSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSA--SMET-TALPG 269

Query: 348 CPESAGAA--TTEALSPPKTPS-LLPPLGLSQSG----------PPGLLPSPSFDSKPPT 394
              +AG +  +T   S P++P   L P   + SG           PG  P+ +      T
Sbjct: 270 STTTAGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPG--PTHTIAFPDST 327

Query: 395 TLLGL----IPAPSMVPATDTKAPPTLQAETATKPQAT---SAP-----SPAPKQSFLFG 442
           T+ G+      + S+  +TDT   P     ++  P++T   S+P     +  P  +   G
Sbjct: 328 TMPGVSQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSG 387

Query: 443 ---------TQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPPGPS------VTA 487
                    +   SP +  +P++S+        F + P S+   P P G +       T 
Sbjct: 388 LLEASTPVHSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTT 447

Query: 488 TAPSSSSLPTT----TSTT---APTFQPVFSSMGPPASVPLPA-----PFFKQTTTPATA 535
              S SS PTT    +STT   +    PV SS    A+ P PA        +++T    +
Sbjct: 448 YHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVEESTAYHRS 507

Query: 536 PTTTAPLFTGLASATS-----------AVAPITSASPSTDSA-SKPAFGFGINSVSSSSV 583
           P +T  +    +S TS           +     S++PST +A +  ++   + S  ++  
Sbjct: 508 PGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHF 567

Query: 584 -STTTSTATAASQPFLFGAPQASAASFTPA--MGSIFQFGKPP-----------ALPTTT 629
             ++T +  +        +P A A +  PA    S+      P           ALP +T
Sbjct: 568 RDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGST 627

Query: 630 T-------VTTFSQS--------LPTAVPTA--TSSSAADFSGFGSTLATSAPATSSQPT 672
           T        TTF  S        LP ++ ++  +  S    S  GST  T+ P +++ P 
Sbjct: 628 TKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPG 687

Query: 673 LTFSNTS-------TPTFNIPFGSSAKSPLPSYPGANPQP-------------AFGAAEG 712
           L+  +T+       T T   P  ++A S  P Y   + +P             A G  E 
Sbjct: 688 LSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEA 747

Query: 713 ---------QPPGAAKPA-LTPSFGSSFTF-----GNSAAPAPATAPTP--APASTIKIV 755
                     P     PA  T   G S TF          PAP T  +    P++T    
Sbjct: 748 SMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGS 807

Query: 756 PAHVPTPIQPTFGGATHSAFGLKATASAF-GAPASSQPA-FGGSTAVFSFGAATSSGFGA 813
           P+ +PT    T   A  +  GL   ++ +  +P S+Q   F  S      G  +++   +
Sbjct: 808 PSSIPT----THISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSS 863

Query: 814 TTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATTGAFSFGAGQSG 873
           TT T SS  S++   +    P ++  S     +  F      P SS T+G     + +S 
Sbjct: 864 TTHTISSAPSTT--SALVEEPTSYHSSPGSTATTHF------PDSSTTSGR----SEEST 911

Query: 874 STATSTPFTGGLGQNALGTT----GQSTPFAFNVGSTTESKPVFGGTATP-------TFG 922
           ++ +S   TG +   A  TT    G+ST    + GS  E+  + G T TP       TF 
Sbjct: 912 ASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGS-METTALPGSTTTPGLSERSTTFH 970

Query: 923 QNTPAPGVGTS-GSSLSFGAS 942
            +  +P    S  S+ S G S
Sbjct: 971 SSPRSPATTLSPASTTSSGVS 991



 Score = 30.8 bits (68), Expect = 6.5
 Identities = 33/124 (26%), Positives = 49/124 (39%), Gaps = 18/124 (14%)

Query: 778 KATASAFGAPASSQPAFGGSTAVFS----FGAATSSGF----GATTQTASSGSSSSVFGS 829
           +A   + G P S Q    G+            +T SGF    G+T  T+  G+++S    
Sbjct: 124 RAEGFSLGLPLSEQARAAGAREKERQETVINHSTFSGFSQITGSTVNTSIGGNTTSASTP 183

Query: 830 TTPSPFTFGGSAAPAGSGSFGINVATPGSSATTGAFSFGAGQSGSTATSTPFTGGLGQNA 889
           ++  PFT            +G++V     S  T  F   +  SG +  ST    G G  A
Sbjct: 184 SSSDPFT--------TFSDYGVSVTFITGSTATKHFLDSSTNSGHSEESTVSHSGPG--A 233

Query: 890 LGTT 893
            GTT
Sbjct: 234 TGTT 237


>gi|89276766 trophinin isoform 5 [Homo sapiens]
          Length = 1431

 Score =  107 bits (267), Expect = 6e-23
 Identities = 160/614 (26%), Positives = 232/614 (37%), Gaps = 79/614 (12%)

Query: 405  MVPATDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFK 464
            + P+T      T           +S+ S A   SF      ++  S  A  +    P   
Sbjct: 761  VAPSTSASFSNTASISFGGTLSTSSSFSSAASISFGCAHSTSTSFSSEASISFGGMPCTS 820

Query: 465  PIFTAPPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAP 524
              F+    S   GP     S T +  +SS    T STTA  F  V S+     S P  + 
Sbjct: 821  ASFSGGVSSSFSGPL--STSATFSGGASSGFGGTLSTTAG-FSGVLSTSTSFGSAPTTST 877

Query: 525  FFKQTTTPATA---PTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSS 581
             F    + +T      +T+  F G  S++ +     S S     +   + GFG     S+
Sbjct: 878  VFSSALSTSTGFGGILSTSVCFGGSPSSSGSFGGTLSTSICFGGSPCTSTGFG--GTLST 935

Query: 582  SVSTTTSTATAA------SQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFS 635
            SVS   S++T+A      S    F    ++ A F  A+ +   FG         T T F 
Sbjct: 936  SVSFGGSSSTSANFGGTLSTSICFDGSPSTGAGFGGALNTSASFGS-----VLNTSTGFG 990

Query: 636  QSLPTAVPTA-TSSSAADFSG-------FGSTLATSAPATSSQPTLTFSNTSTPTFNIPF 687
             ++ T+     T S++  F G       FGS L T+A    +  T T    +  T ++ F
Sbjct: 991  GAMSTSADFGGTLSTSVCFGGSPGTSVSFGSALNTNAGYGGAVSTNTDFGGTLST-SVCF 1049

Query: 688  GSSAKSPLPSYPGANPQPAFGAAEGQPPG-----------AAKPALTPSFGSSFT----F 732
            G S  +        N   +FG A                 +  P   P FG +F+    F
Sbjct: 1050 GGSPSTSAGFGGALNTNASFGCAVSTSASFSGAVSTSACFSGAPITNPGFGGAFSTSAGF 1109

Query: 733  GNSAAPAPATAPTP--------APASTIKIVPAHVPTPIQPTFGGA--THSAFGLKATAS 782
            G + + A     TP        AP++++    AH  +     FGGA  T   FG  +  +
Sbjct: 1110 GGALSTAADFGGTPSNSIGFGAAPSTSVSFGGAHGTSLC---FGGAPSTSLCFGSASNTN 1166

Query: 783  -AFGAPASSQPAFGGSTAV-FSFGAATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGS 840
              FG P S+   F G+T+  F  G +TS+GF       +  S+++ FG    +   FGG 
Sbjct: 1167 LCFGGPPSTSACFSGATSPSFCDGPSTSTGFSF----GNGLSTNAGFGGGLNTSAGFGGG 1222

Query: 841  AAPAGSGSFGINVATPGSSATTGAFSFGAGQSGSTATSTPFTGGLGQNALGTTGQSTPFA 900
               +   S G++     SS   G     AG  G   TST F GGLG +A  + G  T   
Sbjct: 1223 LGTSAGFSGGLST----SSGFDGGLGTSAGFGGGPGTSTGFGGGLGTSAGFSGGLGTSAG 1278

Query: 901  FNVGSTTESKPVFGGTATPTFGQNTPAPGVGTSGSSLSFGASSAPAQGFVGVGPFGSAAP 960
            F  G  T     FGG      G  T A    T G+S  F    + + GF G  P  S   
Sbjct: 1279 FGGGLVTSDG--FGG------GLGTNASFGSTLGTSAGFSGGLSTSDGF-GSRPNASFDR 1329

Query: 961  SFS----IGAGSKT 970
              S     G+GS T
Sbjct: 1330 GLSTIIGFGSGSNT 1343



 Score =  101 bits (251), Expect = 4e-21
 Identities = 161/586 (27%), Positives = 234/586 (39%), Gaps = 103/586 (17%)

Query: 467  FTAPPKSEKEGPTPPGPSVT-ATAPSSS-SLPTTTS-------TTAPTFQPVFS------ 511
            F   P S   G    GP +T   APS+S S   T S       +T+ +F    S      
Sbjct: 741  FNGAPSSS--GGFSGGPGITFGVAPSTSASFSNTASISFGGTLSTSSSFSSAASISFGCA 798

Query: 512  -----SMGPPASVPL------PAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSAS 560
                 S    AS+         A F    ++  + P +T+  F+G AS+       T+A 
Sbjct: 799  HSTSTSFSSEASISFGGMPCTSASFSGGVSSSFSGPLSTSATFSGGASSGFGGTLSTTAG 858

Query: 561  PSTDSASKPAFGFG--INSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQ 618
             S   ++  +FG     ++V SS++ST+T      S    FG   +S+ SF   + +   
Sbjct: 859  FSGVLSTSTSFGSAPTTSTVFSSALSTSTGFGGILSTSVCFGGSPSSSGSFGGTLSTSIC 918

Query: 619  FGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATS-----APATSS---- 669
            FG  P      T T F  +L T+V    SSS +  + FG TL+TS     +P+T +    
Sbjct: 919  FGGSPC-----TSTGFGGTLSTSVSFGGSSSTS--ANFGGTLSTSICFDGSPSTGAGFGG 971

Query: 670  --QPTLTFS---NTSTP---------------TFNIPFGSSAKSPLPSYPGANPQPAFGA 709
                + +F    NTST                + ++ FG S  + +      N    +G 
Sbjct: 972  ALNTSASFGSVLNTSTGFGGAMSTSADFGGTLSTSVCFGGSPGTSVSFGSALNTNAGYGG 1031

Query: 710  AEGQPPG-----------AAKPALTPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVPAH 758
            A                    P+ +  FG +     S   A +T+ + + A +     + 
Sbjct: 1032 AVSTNTDFGGTLSTSVCFGGSPSTSAGFGGALNTNASFGCAVSTSASFSGAVSTSACFSG 1091

Query: 759  VPTPIQPTFGGA--THSAF-GLKATASAFGAPASSQPAFGG--STAVFSFGAA--TSSGF 811
             P    P FGGA  T + F G  +TA+ FG   S+   FG   ST+V SFG A  TS  F
Sbjct: 1092 API-TNPGFGGAFSTSAGFGGALSTAADFGGTPSNSIGFGAAPSTSV-SFGGAHGTSLCF 1149

Query: 812  GATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATTGAFSFG--- 868
            G       + S+S  FGS + +   FGG  + +   S   + +     +T+  FSFG   
Sbjct: 1150 G------GAPSTSLCFGSASNTNLCFGGPPSTSACFSGATSPSFCDGPSTSTGFSFGNGL 1203

Query: 869  ---AGQSGSTATSTPFTGGLGQNALGTTGQSTPFAFNVGSTTESKPVFGGTATPT---FG 922
               AG  G   TS  F GGLG +A  + G ST   F+ G  T S    GG  T T    G
Sbjct: 1204 STNAGFGGGLNTSAGFGGGLGTSAGFSGGLSTSSGFDGGLGT-SAGFGGGPGTSTGFGGG 1262

Query: 923  QNTPAPGVGTSGSSLSFGASSAPAQGF-VGVGPFGSAAPSFSIGAG 967
              T A   G  G+S  FG     + GF  G+G   S   +    AG
Sbjct: 1263 LGTSAGFSGGLGTSAGFGGGLVTSDGFGGGLGTNASFGSTLGTSAG 1308



 Score = 94.0 bits (232), Expect = 6e-19
 Identities = 135/461 (29%), Positives = 197/461 (42%), Gaps = 85/461 (18%)

Query: 543  FTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAP 602
            F+G    T  VAP TSAS S  +    +  FG       ++ST++S ++AAS    FG  
Sbjct: 751  FSGGPGITFGVAPSTSASFSNTA----SISFG------GTLSTSSSFSSAAS--ISFGCA 798

Query: 603  QASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLAT 662
             +++ SF+    +   FG  P    + +    S S    + T+ + S    SGFG TL+T
Sbjct: 799  HSTSTSFSSE--ASISFGGMPCTSASFS-GGVSSSFSGPLSTSATFSGGASSGFGGTLST 855

Query: 663  SAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPG-ANPQPAFGAAEGQPPGAAKPA 721
            +A  +    T T S  S PT +  F SSA S    + G  +    FG +         P+
Sbjct: 856  TAGFSGVLSTST-SFGSAPTTSTVF-SSALSTSTGFGGILSTSVCFGGS---------PS 904

Query: 722  LTPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVPAHVPTPIQPTFGG--ATHSAFGLKA 779
             + SFG + +       +P T+                       FGG  +T  +FG  +
Sbjct: 905  SSGSFGGTLSTSICFGGSPCTS---------------------TGFGGTLSTSVSFGGSS 943

Query: 780  TASA-FGAPASSQPAFGGSTAV-FSFGAA--TSSGFGATTQTAS----SGSSSSVFGSTT 831
            + SA FG   S+   F GS +    FG A  TS+ FG+   T++    + S+S+ FG T 
Sbjct: 944  STSANFGGTLSTSICFDGSPSTGAGFGGALNTSASFGSVLNTSTGFGGAMSTSADFGGTL 1003

Query: 832  PSPFTFGGSAAPAGSGSFG----INVATPGSSATT----GAFSFGAGQSGSTATSTPFTG 883
             +   FGGS  P  S SFG     N    G+ +T     G  S      GS +TS  F G
Sbjct: 1004 STSVCFGGS--PGTSVSFGSALNTNAGYGGAVSTNTDFGGTLSTSVCFGGSPSTSAGFGG 1061

Query: 884  GLGQNALGTTGQSTPFAFNVGSTTE--------SKPVFGGTATPTFG----QNTPAPGVG 931
             L  NA      ST  +F+   +T         + P FGG  + + G     +T A   G
Sbjct: 1062 ALNTNASFGCAVSTSASFSGAVSTSACFSGAPITNPGFGGAFSTSAGFGGALSTAADFGG 1121

Query: 932  TSGSSLSFGASSAPAQGFVGVGP----FGSAAPSFSIGAGS 968
            T  +S+ FGA+ + +  F G       FG  APS S+  GS
Sbjct: 1122 TPSNSIGFGAAPSTSVSFGGAHGTSLCFG-GAPSTSLCFGS 1161



 Score = 85.9 bits (211), Expect = 2e-16
 Identities = 119/466 (25%), Positives = 183/466 (39%), Gaps = 48/466 (10%)

Query: 529  TTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTS 588
            T+T      +T+  F G  S +         S S  SA     G+G       +VST T 
Sbjct: 985  TSTGFGGAMSTSADFGGTLSTSVCFGGSPGTSVSFGSALNTNAGYG------GAVSTNTD 1038

Query: 589  TATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSS 648
                 S    FG   +++A F  A+ +   FG   +   + +    + +  +  P     
Sbjct: 1039 FGGTLSTSVCFGGSPSTSAGFGGALNTNASFGCAVSTSASFSGAVSTSACFSGAPITNPG 1098

Query: 649  SAADFS---GFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQP 705
                FS   GFG  L+T+A    + P+ +    + P+ ++ FG +  + L      +   
Sbjct: 1099 FGGAFSTSAGFGGALSTAADFGGT-PSNSIGFGAAPSTSVSFGGAHGTSLCFGGAPSTSL 1157

Query: 706  AFGAAE------GQPP-------GAAKPALT--PSFGSSFTFGNSAAPAPATAPTPAPAS 750
             FG+A       G PP       GA  P+    PS  + F+FGN  +     A      +
Sbjct: 1158 CFGSASNTNLCFGGPPSTSACFSGATSPSFCDGPSTSTGFSFGNGLS---TNAGFGGGLN 1214

Query: 751  TIKIVPAHVPTPIQPTFGGATHSAF-GLKATASAFGAPASSQPAFGG---STAVFSFGAA 806
            T       + T    + G +T S F G   T++ FG    +   FGG   ++A FS G  
Sbjct: 1215 TSAGFGGGLGTSAGFSGGLSTSSGFDGGLGTSAGFGGGPGTSTGFGGGLGTSAGFSGGLG 1274

Query: 807  TSSGFGATTQTASS-----GSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSAT 861
            TS+GFG    T+       G+++S FGST  +   F G  +   S  FG           
Sbjct: 1275 TSAGFGGGLVTSDGFGGGLGTNAS-FGSTLGTSAGFSGGLST--SDGFGSRPNASFDRGL 1331

Query: 862  TGAFSFGAGQSGSTATSTPFTGGLGQNALGTTGQSTPFAFNVGSTTESKPVFGGTATPTF 921
            +    FG+G +    TST FTG    +   ++G S+   F+ G +T       G +T  F
Sbjct: 1332 STIIGFGSGSN----TSTGFTGEPSTSTGFSSGPSSIVGFSGGPST-GVGFCSGPSTSGF 1386

Query: 922  --GQNTPAPGVGTSGSSLSFGASSAPAQGFVGVGPFGSAAPSFSIG 965
              G +T A   G   +   FG   + + GF G G     A  FS G
Sbjct: 1387 SGGPSTGAGFGGGPNTGAGFGGGPSTSAGF-GSGAASLGACGFSYG 1431



 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 73/238 (30%), Positives = 107/238 (44%), Gaps = 31/238 (13%)

Query: 757 AHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVF--------SFGAATS 808
           A   T +  + G +T + F   A+ S  GAP+SS    GG    F        SF    S
Sbjct: 715 ADASTNVNFSRGASTRAGFSDGASISFNGAPSSSGGFSGGPGITFGVAPSTSASFSNTAS 774

Query: 809 SGFGATTQTASSGSS--SSVFG---STTPS-----PFTFGGSAAPAGSGSFGINVATPGS 858
             FG T  T+SS SS  S  FG   ST+ S       +FGG    + S S G++ +  G 
Sbjct: 775 ISFGGTLSTSSSFSSAASISFGCAHSTSTSFSSEASISFGGMPCTSASFSGGVSSSFSGP 834

Query: 859 SATTGAFSFGA--GQSGSTATSTPFTGGLGQNALGTTGQSTPFAFNVGSTTESKPVFGG- 915
            +T+  FS GA  G  G+ +T+  F+G L  +    +  +T   F+   +T +   FGG 
Sbjct: 835 LSTSATFSGGASSGFGGTLSTTAGFSGVLSTSTSFGSAPTTSTVFSSALSTSTG--FGGI 892

Query: 916 -TATPTFGQNTPAPGV--GTSGSSLSFGASSAPAQGFVGVGPFGSAAPSFSIGAGSKT 970
            + +  FG +  + G   GT  +S+ FG S   + GF      G+ + S S G  S T
Sbjct: 893 LSTSVCFGGSPSSSGSFGGTLSTSICFGGSPCTSTGF-----GGTLSTSVSFGGSSST 945



 Score = 47.4 bits (111), Expect = 7e-05
 Identities = 51/193 (26%), Positives = 81/193 (41%), Gaps = 29/193 (15%)

Query: 783 AFGAPASSQPAFGGSTAV-FSFGAATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSA 841
           +F   A +Q     ST V FS GA+T +GF       S G+S S           F G+ 
Sbjct: 704 SFEIEARAQENADASTNVNFSRGASTRAGF-------SDGASIS-----------FNGAP 745

Query: 842 APAGSGS------FGINVATPGSSATTGAFSFGAGQSGSTATSTPFTGGLGQNALGTTGQ 895
           + +G  S      FG+  +T  S + T + SFG   S S++ S+  +   G     +T  
Sbjct: 746 SSSGGFSGGPGITFGVAPSTSASFSNTASISFGGTLSTSSSFSSAASISFGCAHSTSTSF 805

Query: 896 STPFAFNVGSTTESKPVFGGTATPTFGQNTPAPGVGTSGSSLSFGASSAPAQGFVGV--- 952
           S+  + + G    +   F G  + +F          + G+S  FG + +   GF GV   
Sbjct: 806 SSEASISFGGMPCTSASFSGGVSSSFSGPLSTSATFSGGASSGFGGTLSTTAGFSGVLST 865

Query: 953 -GPFGSAAPSFSI 964
              FGSA  + ++
Sbjct: 866 STSFGSAPTTSTV 878


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score =  102 bits (253), Expect = 2e-21
 Identities = 190/825 (23%), Positives = 309/825 (37%), Gaps = 107/825 (12%)

Query: 104  PGSLKRGLNSQSSDDHLNKRSRSSSMSSLTG-AYTSGIP---SSSRNAITSSYSSTRGIS 159
            P   KR  +  S   H   RSR+  +S     + TS +    S SR ++T   S +R  S
Sbjct: 1858 PAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRA-S 1916

Query: 160  QLWKRNGPSSSPFSSPASSRSQTP--ERPAKKIREEELCHHSSSSTPLAADKESQGEKAA 217
             + +R   S +P  +   SRS+TP   R ++          S S TP    + S+     
Sbjct: 1917 PVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSR--- 1973

Query: 218  DTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTLP---------PPPQLGYSITA 268
             T+P  ++ S S+++P +  + + +   +  RR    T P          PP +     +
Sbjct: 1974 -TSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRS 2032

Query: 269  EDLDLEKKASLQWFNQALEDKSDAAS-------NSVTETPPTTQ--PSFTFTLPAAATAS 319
                L +K S      A+  +S + +        S+T +PP  +   +   +   + +A+
Sbjct: 2033 RTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSAT 2092

Query: 320  PPTSL--LAPSTNPLLESLKKMQ--TPPSLPPCP--ESAGAATTEALSPPKTP-SLLPPL 372
            PP +       T P+  +  +M   + PS+ P P          E L   +TP S+L   
Sbjct: 2093 PPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQA 2152

Query: 373  GLSQSGPPG-LLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAETATKPQATSAP 431
            G S    PG  +P     S P       I       +  T  PP   +      + +  P
Sbjct: 2153 GGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVP 2212

Query: 432  SPAPKQSFLFG-TQNTSPSSPAAPAASS--ASPMFKPIFTAPPKSEKEGPTPPGPSV--- 485
            +P P  S       N +   PAA AA+   AS     I TA   ++   P          
Sbjct: 2213 APVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLAS 2272

Query: 486  --TATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAP------- 536
              TA APS+ +L    + TAP      +  G      L A     + TP TA        
Sbjct: 2273 PRTAVAPSAVNLADPRTPTAPAV----NLAGARTPAALAALSLTGSGTPPTAANYPSSSR 2328

Query: 537  TTTAPLFTGLASATSA--VAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAAS 594
            T  AP    L    SA   AP+  A   T +A  PA      S++S+ ++   S A   S
Sbjct: 2329 TPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPA------SLTSARMAPALSGANLTS 2382

Query: 595  QPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTF-------------SQSL-PT 640
                  A +  +   +P +    +   PP+ P+ + +T+              SQSL P 
Sbjct: 2383 PRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPP 2442

Query: 641  AVPTATSSSAADFSGFGSTL-ATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYP 699
            A     S   + FS     L A + P   SQ   + +  +T +           P P  P
Sbjct: 2443 AQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVP 2502

Query: 700  GAN---PQPAFGAAEGQPPGAAKPAL------------------TPSFGSSFTFGNSAAP 738
             ++   P  + GA +     A +PA                   + S  SS + G+S++ 
Sbjct: 2503 HSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSD 2562

Query: 739  APATAPTPAPASTIKIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGST 798
            +  ++    P   +K VP+  P P +    G        K    +  + +SS  +   S 
Sbjct: 2563 SEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSS- 2621

Query: 799  AVFSFGAATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAP 843
                  +++SS   +++ ++SS SSSS   S++PSP   G  A P
Sbjct: 2622 ------SSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALP 2660



 Score = 90.1 bits (222), Expect = 9e-18
 Identities = 155/697 (22%), Positives = 251/697 (36%), Gaps = 111/697 (15%)

Query: 120  LNKRSRSSSMSSLTG--AYTSGIPSSSRNAITSSYS--STRGISQLWKRNGPSSSPFSSP 175
            + +RSRS +  +  G  + T   P+  R + + S S  S        + +  S +P  + 
Sbjct: 2050 IRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVAL 2109

Query: 176  ASSRSQTPERPAKKIREEELCHH-------SSSSTPLAADKESQGEKAADTTPRKKQNSN 228
             SSR     RP+      + C          SS TP++  +++ G       PR   +  
Sbjct: 2110 NSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQR 2169

Query: 229  SQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALED 288
            + S P +  Q +  + L     G     PPP      + A    +     L     A   
Sbjct: 2170 T-SVPENHAQSRIALALTAISLGT--ARPPPSMSAAGLAARMSQVPAPVPLMSLRTA--- 2223

Query: 289  KSDAASNSVTETPPTTQPSFTFTLPAAATASPPTSL-LAPSTNPLLESLKKMQTPPSL-- 345
                A+N  +  P  +  +    L +A T + PT++ LA S  P   +   + +P +   
Sbjct: 2224 ---PAANLASRIPAASAAAMN--LASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVA 2278

Query: 346  PPCPESAGAATTEA----LSPPKTPSLLPPLGLSQSG-PPGLLPSPSFDSKP-------- 392
            P     A   T  A    L+  +TP+ L  L L+ SG PP     PS    P        
Sbjct: 2279 PSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANL 2338

Query: 393  ----------PTTLLGLIPAPSMVPATDTKA--PPTLQAETATKPQA------------- 427
                      P  + G   A ++ PA+ T A   P L     T P+              
Sbjct: 2339 VGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTS 2398

Query: 428  --------TSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPT 479
                    +  P  AP QS +   +  SPSS    A S +          P + +   P 
Sbjct: 2399 PPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQS-------LLPPAQDQPRSPV 2451

Query: 480  PPGPS------VTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPA 533
            P   S      +  T P + S   ++   A T        G   SVP P         P 
Sbjct: 2452 PSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGM-LSVPAPGVPHSDVGEPP 2510

Query: 534  TAPTTTAPLFTGLASATSAVAPITS--ASPSTDSASKPAFGFGINSVSSSSVSTTTSTAT 591
             +     P      SA +A+ P     +S S+ S+S  +     +S SSSS  +++S + 
Sbjct: 2511 ASTGAQQP------SALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSE 2564

Query: 592  AASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAA 651
             +S P           S TPA     + G+PP            +  P      +SSS++
Sbjct: 2565 GSSLPVQPEVALKRVPSPTPAPKEAVREGRPP------------EPTPAKRKRRSSSSSS 2612

Query: 652  DFSGFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAE 711
              S   S+ ++S+ ++SS  + + S++S+ +      SS+ SP P+ PG    P   + +
Sbjct: 2613 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS------SSSSSPSPAKPGPQALPKPASPK 2666

Query: 712  GQPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAP 748
              PPG  +         S     S + +P     P+P
Sbjct: 2667 KPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSP 2703



 Score = 86.3 bits (212), Expect = 1e-16
 Identities = 234/1033 (22%), Positives = 369/1033 (35%), Gaps = 174/1033 (16%)

Query: 5    PVTVRIAPPDRRFSRSAIPEQIISSTLSSPSSNAPDPCAKETVLSALKEKKKKRTVEEED 64
            P T    PP RR SRS+ PE    + LS  S +A    + ET        ++  +V   +
Sbjct: 1678 PKTKSRTPPRRRSSRSS-PELTRKARLSRRSRSASS--SPETRSRTPPRHRRSPSVSSPE 1734

Query: 65   QIFLDGQENKRRRHDSSGSGHSAFEPLVASGVPASFVPKPGSLKRGLN------------ 112
                +   + RRR  +S            S    S  PKP  L+R  +            
Sbjct: 1735 PA--EKSRSSRRRRSASSP-----RTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRR 1787

Query: 113  ---SQSSDDHLNKRSRSSSMSSLTGAYTSGIPSSSRNAITSSYSSTRGISQLWKRNGPSS 169
               S SS     +R RS S S +T     G    SR+      S T       +R G S 
Sbjct: 1788 RDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSR----RRRGRSR 1843

Query: 170  SPFSSPASSRSQTPERPAKKIREEE---LCHHSSSSTPLAADKESQGEKAADTTPRKKQN 226
            +P +S   SRS+T   P K+ R          S S TPL + + S+      T+P  ++ 
Sbjct: 1844 TPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSR----TSPVSRRR 1899

Query: 227  SNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQAL 286
            S S++   S  +R+ + +  P  R    +  PP     S +       +  S        
Sbjct: 1900 SRSRT---SVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRS-------- 1948

Query: 287  EDKSDAASNSVTETPPTTQPSFTFTLPAAATASPPTSLLAPS-TNPLLESLKKMQTPPSL 345
                     S + TPP T+        + +  SP T   + S T+P+     + +T P  
Sbjct: 1949 RTPPVTRRRSRSRTPPVTRRR------SRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVT 2002

Query: 346  PPCPESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLL----GLIP 401
                 S  +  T   S  +TP   P +         LLP     S+ P  +        P
Sbjct: 2003 RRRSRSRTSPVTRRRSRSRTP---PAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTP 2059

Query: 402  APSMVPATDTKAPPTLQAETAT---KPQATSAPSPAPK---------------QSFLFGT 443
              +    + T++PP ++  +A+     ++ SA  PA +               +   F  
Sbjct: 2060 RTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSR 2119

Query: 444  QNTSPS------SPAA--PAASSASPMFKPIFTAPPKSEKEGPTPPGPSVTAT------A 489
             + SP+      SP    P  SS +PM   +      S  +GP P  P    T      A
Sbjct: 2120 PSMSPTPLDRCRSPGMLEPLGSSRTPM--SVLQQAGGSMMDGPGPRIPDHQRTSVPENHA 2177

Query: 490  PSSSSLPTTT---STTAPTFQPVFSSMGPPA---SVPLPAPFFKQTTTPATAPTTTAPLF 543
             S  +L  T     T  P   P  S+ G  A    VP P P     T PA    +  P  
Sbjct: 2178 QSRIALALTAISLGTARPP--PSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAA 2235

Query: 544  TG----LASATSAVAPI--------TSASPSTDSASKPAFGFGINSVSSSSVSTTTSTAT 591
            +     LASA +   P         T A+ +  + + P      ++V+ +   T T+ A 
Sbjct: 2236 SAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAV 2295

Query: 592  ---AASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTA-VPTATS 647
                A  P    A   + +   P   +     + P  P +  +     +  TA V  A S
Sbjct: 2296 NLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGS 2355

Query: 648  SSAADFSGFGSTLATSAPATS----SQPTLTFS-------NTSTPTFN-----IPFGSSA 691
             +AA  +    T A  APA S    + P +  S        TS P  +      P  + +
Sbjct: 2356 RTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPS 2415

Query: 692  KSPLPSYPGANPQPAFGAAEGQ---PPGAAKP-ALTPSFGSSFTFGNSAAPAPATAP--- 744
            +S + S    +P    G A  Q   PP   +P +  PS  S  +    A   P       
Sbjct: 2416 QSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSL 2475

Query: 745  -TPAPASTIKIVPAH-----VPTPIQPTFGGATHSAFGLKATASAFGAP---ASSQPAFG 795
             + A A+T      H     VP P      G  HS  G    ++    P   A+ QPA  
Sbjct: 2476 SSGAVATTTSSAGDHNGMLSVPAP------GVPHSDVGEPPASTGAQQPSALAALQPAKE 2529

Query: 796  --GSTAVFSFGAATSSGFGATTQTASSGSSSSVF-GSTTP--SPFTFGGSAAPAGSGSFG 850
               S++  S  +++SS   +++ ++SSGSSSS   GS+ P           +P  +    
Sbjct: 2530 RRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEA 2589

Query: 851  INVATP------------GSSATTGAFSFGAGQSGSTATSTPFTGGLGQNALGTTGQSTP 898
            +    P             SS+++ + S  +  S S+++S+  +     ++  ++  S+P
Sbjct: 2590 VREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSP 2649

Query: 899  FAFNVGSTTESKP 911
                 G     KP
Sbjct: 2650 SPAKPGPQALPKP 2662



 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 221/1093 (20%), Positives = 368/1093 (33%), Gaps = 158/1093 (14%)

Query: 13   PDRRFSRSAIPEQIISSTLSSP--SSNAPDPCAKETVLSALKEKKKKRTVEEEDQIFLDG 70
            P R+ SRS    ++ S +  SP  S +   P  K+   +A + +    +   E +     
Sbjct: 1572 PLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDS-SPEPKAPAPR 1630

Query: 71   QENKRRRHDSSGSGHSAFEPLVASGVPAS--FVPKPGSLKRGLNSQSSDDHLNKRS---- 124
               +R R  SS  G     P  +S   +S    PK  + +RG  S+SS +   K      
Sbjct: 1631 ALPRRSRSGSSSKGRGP-SPEGSSSTESSPEHPPKSRTARRG--SRSSPEPKTKSRTPPR 1687

Query: 125  RSSSMSSLTGAYTSGIPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRSQTPE 184
            R SS SS      + +   SR+A  SS   TR  +    R  PS S       SRS    
Sbjct: 1688 RRSSRSSPELTRKARLSRRSRSA--SSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRR 1745

Query: 185  RPAKKIREEELCHHSSSSTP----LAADKESQGEKAADTTPRKKQNSNSQSTP------- 233
            R A   R +       S +P    L   +     +   TT R+ ++ +SQST        
Sbjct: 1746 RSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSR 1805

Query: 234  ----------GSSGQRKRKVQLLPS-------RRGEQLTLPPPPQLGYSITA-------- 268
                      G SG   R      S       RRG   T P   +   S T+        
Sbjct: 1806 SRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSR 1865

Query: 269  ------------EDLDLEKKASLQWFNQALEDKSDAASNSVTETPPTTQPSFTFTLPAAA 316
                            L  +   +     +  +   +  SVT     ++ S      + +
Sbjct: 1866 SRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRS 1925

Query: 317  TASPPTSLLAPSTNPLLESLKKMQTPP--------SLPPCPESAGAATTEALSPPKTPSL 368
               P T   + S  P      + +TPP          PP       + T  ++  ++ S 
Sbjct: 1926 RTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSR 1985

Query: 369  LPPL----GLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTL--QAETA 422
              P+      S++ P     S S  S P T        P  +        P L  +   +
Sbjct: 1986 TSPVTRRRSRSRTSPVTRRRSRSRTS-PVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRS 2044

Query: 423  TKPQATSAPSPAPKQSFLFGTQNTSPSSPA--APAASSASPMFKPIFTAPPKSEKEGPTP 480
              P A    S +       G ++ + S PA    +AS +S       T P      G   
Sbjct: 2045 RSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRT 2104

Query: 481  PGPSVTA------TAPSSSSLPTTTSTTAPTFQPVFSSMGPPASV----------PLP-A 523
            P  ++ +      + PS S  P     +    +P+ SS  P + +          P P  
Sbjct: 2105 PPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRI 2164

Query: 524  PFFKQTTTPAT-APTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSS 582
            P  ++T+ P   A +  A   T ++  T+   P  SA+      S+      + S+ ++ 
Sbjct: 2165 PDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAP 2224

Query: 583  VSTTTSTATAASQPFLFGAPQASAA---------SFTPAMGSIFQFGKP----------- 622
             +   S   AAS   +  A   + A         S TPA  +      P           
Sbjct: 2225 AANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNL 2284

Query: 623  --PALPTTTTVTTFSQSLPTAVP------TATSSSAADFSGFGSTLATSAPATSSQP--- 671
              P  PT   V       P A+       + T  +AA++     T    A A    P   
Sbjct: 2285 ADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSA 2344

Query: 672  ----TLTFSNTSTPTFNIPFGSSAKSPLPSYPGAN------PQPAFGAAEGQ--PP--GA 717
                 +  + + T     P   ++    P+  GAN      P  A+    G+  PP    
Sbjct: 2345 HATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDR 2404

Query: 718  AKPALTPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVPAHVP-TPIQPTFG-------G 769
            A+    PS  S     +  AP+P++    AP+ ++       P +P+   F         
Sbjct: 2405 ARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIA 2464

Query: 770  ATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAATSSGFGATTQTASSGSSS-SVFG 828
             T    G ++ +S  GA A++  + G    + S  A            AS+G+   S   
Sbjct: 2465 QTTPVAGSQSLSS--GAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALA 2522

Query: 829  STTPSPFTFGGSAAPAGSGSFGINVATPGSSATTGAFSFGAGQSGSTATSTPFTGGLGQN 888
            +  P+      S++ + S S     ++  SS+++ + S G+  S S  +S P    +   
Sbjct: 2523 ALQPAKERRSSSSSSSSSSS-----SSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALK 2577

Query: 889  ALGTTGQSTPFAFNVGSTTESKPVFGGTATPTFGQNTPAPGVGTSGSSLSFGASSAPAQG 948
             + +   +   A   G   E  P      + +   ++ +    +S SS S  +SS+ +  
Sbjct: 2578 RVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2637

Query: 949  FVGVGPFGSAAPS 961
                    S++PS
Sbjct: 2638 SSSSSSSSSSSPS 2650



 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 89/374 (23%), Positives = 138/374 (36%), Gaps = 45/374 (12%)

Query: 97  PASFVPKPGSLKRGLNSQSSDDHLNKRSRSSSMSSLTGAYTSGIPSSSRNAITSSYSSTR 156
           PA   PKP SL R  +S  S     K+ +                   R   + S S  R
Sbjct: 163 PAPEPPKPYSLVRESSSSRSPTPKQKKKKKKK---------------DRGRRSESSSPRR 207

Query: 157 GISQLWKRNGPSSSPFSSPASSRSQTPERPAKKIREEELCHHSSSSTPLAADKESQGEKA 216
              +  K+    S   S     RS TP+  +K+  +++    S S+TP    + +    +
Sbjct: 208 ERKKSSKKKKHRSESESKKRKHRSPTPK--SKRKSKDKKRKRSRSTTPAPKSRRAHRSTS 265

Query: 217 ADT-----TPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDL 271
           AD+     T R +  S +  T  ++    R       RRGE       P      T+   
Sbjct: 266 ADSASSSDTSRSRSRSAAAKTH-TTALAGRSPSPASGRRGEG----DAPFSEPGTTSTQR 320

Query: 272 DLEKKASLQWFNQALEDKS-DAASNSVTETPPTTQPSFTFTLPAAATASPPTSLLAPSTN 330
               + + +  +   EDK  D    S T   P+ + S T   P A     PT LLA    
Sbjct: 321 PSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPA-----PTPLLAERHG 375

Query: 331 PLLESLKKMQTPPSLPPCPESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLP---SPS 387
              + L    TP S  P    + A+ T   SPPK+P  LP    S+S PP   P   S  
Sbjct: 376 GSPQPLAT--TPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRH 433

Query: 388 FDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNTS 447
             S P +      PAP+     +  + PT +  +  + +   + S  P +      ++ S
Sbjct: 434 ASSSPESPK----PAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRM---GRSRS 486

Query: 448 PSSPAAPAASSASP 461
           P++     + S +P
Sbjct: 487 PATAKRGRSRSRTP 500



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 166/807 (20%), Positives = 263/807 (32%), Gaps = 135/807 (16%)

Query: 11   APPDRRFSRSAIPEQIISSTLSSPSSNAPDPCAKETVLSALKEKKKKRTVEEEDQIFLDG 70
            A P R  S    PE++  S+ S  S  +P P       S+  E  K        +     
Sbjct: 397  ASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSS 456

Query: 71   QENKRRRH-----DSSGS-------GHSAFEPLVASGVPASFVPKPGSLKRGLNSQ---- 114
              +K R H     D S S       G S        G   S  P      R  + Q    
Sbjct: 457  PTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRS 516

Query: 115  --------SSDDHLNKRSRS---SSMSSLTGAYTSGIPSSSRNAITSSYS-STRG--ISQ 160
                    S       RSRS      S        G   S+R   + S S +TRG   S+
Sbjct: 517  RSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSR 576

Query: 161  LWKRNGPSSSPFSSPASSRSQTPERPAKKIREEELCHHSSSSTPLAADKESQG---EKAA 217
               R G S S   +   SRS+TP R   + R       S S TP      ++     ++ 
Sbjct: 577  TPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSR 636

Query: 218  DTTPRKKQNSNSQSTPGSSGQRK--------------------RKVQLLPSRRGEQLTLP 257
              +P ++   +   TP   G+ +                    R     P+RRG   +  
Sbjct: 637  SRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRT 696

Query: 258  P--------------------PPQLGYSITAEDLDLEKKASLQ--WFNQALEDKSDAASN 295
            P                    P + G S ++ +   + + S +    N + E K    S+
Sbjct: 697  PRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISS 756

Query: 296  --SVTETPPTTQPSFTFTLPAAATASPPTSLLAPSTNP------LLESLKKMQTPP---- 343
              S + + P ++     +L  + + S P       T P        +   K +TPP    
Sbjct: 757  RRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSR 816

Query: 344  --SLPPCPESAGAATTEALS------------PPKTPSLLPPLGLSQSGPPGLLPSPSFD 389
              S PP  + +   + ++ S            PP+  S+  P    QS  P       F+
Sbjct: 817  SSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTP--QRRSCFE 874

Query: 390  SKPPTTLLGLIPAPSMVPATDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNTSPS 449
            S P   L    P+     +    +PP +++ T  +   + + SP PK   +   +  S S
Sbjct: 875  SSPDPELKSRTPSRH---SCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHS 931

Query: 450  SPAAPAASSASPMFKPIFTAPPKSEKEGPTPPGPSVTATAPS---SSSLPTTTSTTAPTF 506
              ++P+ S  +       T P +S    P     S      S   SSS  T      P  
Sbjct: 932  GSSSPSPSRVTSR-----TTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPR 986

Query: 507  QPVFSSMGPPASVPL---PAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPST 563
            Q    S+ P   V     P P    + +P     +   L      + S  A + S++P  
Sbjct: 987  QSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPG 1046

Query: 564  DSASKPAFGFGINSV-----SSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQ 618
            +S       FG++S+     S +S    + T++   +     +P   + S T   G   +
Sbjct: 1047 ESY------FGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSR 1100

Query: 619  FGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTFSNT 678
               P     + +     +   +A P   S  + + S F S  ++S P   S   L  S  
Sbjct: 1101 SSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSD-SSSYPTVDSNSLLGQSRL 1159

Query: 679  STPTFNIPFGSSAKSPLPSYPGANPQP 705
             T        S  K  LP    A   P
Sbjct: 1160 ETAE------SKEKMALPPQEDATASP 1180



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 135/624 (21%), Positives = 219/624 (35%), Gaps = 108/624 (17%)

Query: 75   RRRHDSSGSGHSAFEPLVASGVPASFVPKPGSLKRGLNSQSSDDHLNK------RSRSSS 128
            R R  +   G S    LV  G   S  P+    +RG  S SS +  NK      RSRS+S
Sbjct: 691  RSRSRTPRRGRSRSRSLVRRGRSHSRTPQ----RRG-RSGSSSERKNKSRTSQRRSRSNS 745

Query: 129  MSSLTGAYTSGIPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSS--PASSRSQTPERP 186
               +  +  S   S S ++  S   S   + +    + P     S   P  SRS + +  
Sbjct: 746  SPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPK 805

Query: 187  AKKIREEELCHHSSSSTPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQRKRKVQLL 246
            AK          SSS  P    K    +  + ++P  K  S +    GS    +   Q +
Sbjct: 806  AKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSV 865

Query: 247  PSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETPPTTQP 306
              +R       P P+                        L+ ++ +  +    +PP  + 
Sbjct: 866  TPQRRSCFESSPDPE------------------------LKSRTPSRHSCSGSSPPRVKS 901

Query: 307  SFTFTLPAAATASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALSPPKTP 366
            S       + ++SP   + A      + S ++     S  P P    + TT    P ++ 
Sbjct: 902  STPPRQSPSRSSSPQPKVKA------IISPRQRSHSGSSSPSPSRVTSRTT----PRRSR 951

Query: 367  SLLPPLGLSQSGPPGLLP--SPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAETATK 424
            S+ P   +       LLP  S S  S P T +    P P    +      P ++A+T   
Sbjct: 952  SVSPCSNVESR----LLPRYSHSGSSSPDTKVKPETP-PRQSHSGSISPYPKVKAQTPPG 1006

Query: 425  PQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPPG-- 482
            P  + + SP P++        + P S +  A   +S                  TPPG  
Sbjct: 1007 PSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSS------------------TPPGES 1048

Query: 483  ----PSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAP--FFKQTTTPATAP 536
                 S+     S +S    + T++P  +   S      S    +P     ++++P T  
Sbjct: 1049 YFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTEL 1108

Query: 537  TTTAPL------FTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTA 590
             + +P+      F+      S ++P  S   S DS+S P       +V S+S+   +   
Sbjct: 1109 ASRSPIRQDRGEFSASPMLKSGMSPEQSRFQS-DSSSYP-------TVDSNSLLGQSRLE 1160

Query: 591  TAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSA 650
            TA S+  +   PQ  A +  P      +F   P      +   F  +L T          
Sbjct: 1161 TAESKEKMALPPQEDATASPPRQKD--KFSPFPVQDRPESSLVFKDTLRT--------PP 1210

Query: 651  ADFSGFGSTLAT----SAPATSSQ 670
             + SG GS+  T    SA  TSSQ
Sbjct: 1211 RERSGAGSSPETKEQNSALPTSSQ 1234



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 55/236 (23%), Positives = 88/236 (37%), Gaps = 22/236 (9%)

Query: 80   SSGSGHSAFEPLVASGVPASFVPKPG--------SLKRGLNSQSSDDHLNKRSRSSSMSS 131
            SS   H+    + A GVP S V +P         S    L         +  S SSS SS
Sbjct: 2485 SSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSS 2544

Query: 132  LTGAYTSGIPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRSQTPERPAKKIR 191
             + + +S   SS  ++  S  SS     ++  +  PS +P    A    + PE    K +
Sbjct: 2545 SSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRK 2604

Query: 192  EEELCHHSSSSTPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRG 251
                   SSSS+  ++   S    ++ ++     +S+S S+  S    K   Q LP    
Sbjct: 2605 RRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPAS 2664

Query: 252  EQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETPPTTQPS 307
             +   PPP +       + +D            +L D    + + V    P+ QPS
Sbjct: 2665 PK--KPPPGERRSRSPRKPID------------SLRDSRSLSYSPVERRRPSPQPS 2706



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 62/254 (24%), Positives = 107/254 (42%), Gaps = 39/254 (15%)

Query: 34   PSSNAPDPCA-----KETVLSALKEKKKKRTVEEEDQIFLDGQENKRRRHDSSGSGHSA- 87
            P S+  +P A     + + L+AL+  K++R+             +      SS SG S+ 
Sbjct: 2502 PHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSS 2561

Query: 88   --------FEPLVASGVPASFVPKPG-SLKRGLNSQSSDDHLNKRSRSSSMSSLTGAYTS 138
                     +P VA     S  P P  +++ G   + +     +RS SSS SS + + +S
Sbjct: 2562 DSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSS 2621

Query: 139  GIPSSSRNAITSSYSSTRGISQLWK------RNGPSSSPFSS------PASSRSQTPERP 186
               SSS ++ +SS SS+   S          + GP + P  +      P   RS++P +P
Sbjct: 2622 SSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKP 2681

Query: 187  AKKIREEELCHHSSSSTPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQRKRKVQLL 246
               +R+      S S +P+   + S        +PR +Q+S+S+     S + +R     
Sbjct: 2682 IDSLRDS----RSLSYSPVERRRPS-----PQPSPRDQQSSSSER---GSRRGQRGDSRS 2729

Query: 247  PSRRGEQLTLPPPP 260
            PS +  + T  P P
Sbjct: 2730 PSHKRRRETPSPRP 2743



 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 69/320 (21%), Positives = 120/320 (37%), Gaps = 43/320 (13%)

Query: 165 NGPSSSPFSSPASSRSQTPE--RPAKKIREEELCHHSSSSTPLAADKESQGEKAADTTPR 222
           +G S  P      ++   PE  +P   +RE       +        K+ +G ++  ++PR
Sbjct: 147 DGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPR 206

Query: 223 ---------KKQNSNSQSTP----GSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAE 269
                    KK  S S+S        + + KRK +    +R    T  P  +  +  T+ 
Sbjct: 207 RERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSA 266

Query: 270 D--------LDLEKKASLQWFNQALEDK--SDAASNSVTETPPTTQPSFTFTLPAAATAS 319
           D            + A+ +    AL  +  S A+        P ++P  T T      +S
Sbjct: 267 DSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTST---QRPSS 323

Query: 320 PPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALSPPKTPSLLPPLGLSQSGP 379
           P T+   PS +P  +  K  +   +  P P    ++T      P+ P+  P L     G 
Sbjct: 324 PETATKQPS-SPYEDKDKDKKEKSATRPSPSPERSST-----GPEPPAPTPLLAERHGGS 377

Query: 380 PGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAETATKPQATSAPSPAPKQSF 439
           P  L +     +P       +  PS    T  ++PP    +      + S+P P+P+ + 
Sbjct: 378 PQPLATTPLSQEP-------VNPPSEASPTRDRSPPKSPEKLPQSSSSESSP-PSPQPTK 429

Query: 440 LFGTQNTSPSSP-AAPAASS 458
           +    ++SP SP  APA  S
Sbjct: 430 VSRHASSSPESPKPAPAPGS 449



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 77/349 (22%), Positives = 122/349 (34%), Gaps = 79/349 (22%)

Query: 176 ASSRSQTPERPAKKIREEELCHHSSSSTPLAADKESQGEKAADTTPRKKQNSNSQSTPGS 235
           +SSRS TP++  KK ++++    S SS+P    K+S  +K   +    K+  +   TP S
Sbjct: 178 SSSRSPTPKQKKKK-KKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKS 236

Query: 236 SGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASN 295
               KRK +    +R    T  P  +  +  T+                     +D+AS+
Sbjct: 237 ----KRKSKDKKRKRSRSTTPAPKSRRAHRSTS---------------------ADSASS 271

Query: 296 SVTETPPTTQPSFTFTLPAAATASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAA 355
           S T    +          +AA  +  T+L   S +P      +   P S P      G  
Sbjct: 272 SDTSRSRSR---------SAAAKTHTTALAGRSPSPASGRRGEGDAPFSEP------GTT 316

Query: 356 TTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPP 415
           +T+  S P+T +  P              S  ++ K           PS  P   +  P 
Sbjct: 317 STQRPSSPETATKQP--------------SSPYEDKDKDKKEKSATRPSPSPERSSTGP- 361

Query: 416 TLQAETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEK 475
                          P+P P    L   ++     P A    S  P+  P   A P  ++
Sbjct: 362 -------------EPPAPTP----LLAERHGGSPQPLATTPLSQEPV-NPPSEASPTRDR 403

Query: 476 EGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAP 524
             P  P        P SSS  ++  +  PT     +S  P +  P PAP
Sbjct: 404 SPPKSP-----EKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAP 447



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 89/412 (21%), Positives = 152/412 (36%), Gaps = 50/412 (12%)

Query: 131  SLTGAYTSGIPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSP---ASSRSQTPERPA 187
            SLTG   SG P ++ N  +SS +     S      GP S+  ++P   A SR+     PA
Sbjct: 2310 SLTG---SGTPPTAANYPSSSRTPQAPASA--NLVGPRSAHATAPVNIAGSRTAAALAPA 2364

Query: 188  KKIREEEL-----CHHSSSSTPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQRKRK 242
                          + +S   PL+A +   G     T+P     + S++ P +  Q +  
Sbjct: 2365 SLTSARMAPALSGANLTSPRVPLSAYERVSGR----TSPPLLDRARSRTPPSAPSQSRMT 2420

Query: 243  VQLLPS---RRGE---QLTLPP-------PPQLGYS-----ITAEDLDLEKKASLQWFNQ 284
             +  PS   R G+   Q  LPP       P    +S     + A+   +    SL     
Sbjct: 2421 SERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAV 2480

Query: 285  ALEDKSDAASNSVTETPPTTQPSFTFTLPAAATASPPTSLLA---PSTNPLLESLKKMQT 341
            A    S    N +   P    P      P A+T +   S LA   P+      S     +
Sbjct: 2481 ATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSS 2540

Query: 342  PPSLPPCPESAGAATTEALSPPKTPSLLP---PLGLSQSGPPGLLPSPSF-DSKPPTTLL 397
              S      S+ ++++ + S     S LP    + L +   P   P  +  + +PP    
Sbjct: 2541 SSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPE--- 2597

Query: 398  GLIPAPSMVPATDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAAS 457
               P P+      + +  +  + +++   ++S+ S +   S    + ++S SS  +PA  
Sbjct: 2598 ---PTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKP 2654

Query: 458  SASPMFKPIF-TAPPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQP 508
                + KP     PP  E+   +P  P + +   S S   +      P+ QP
Sbjct: 2655 GPQALPKPASPKKPPPGERRSRSPRKP-IDSLRDSRSLSYSPVERRRPSPQP 2705



 Score = 40.0 bits (92), Expect = 0.011
 Identities = 85/384 (22%), Positives = 133/384 (34%), Gaps = 85/384 (22%)

Query: 197  HHSSSSTPLAADK------ESQGEKAADTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRR 250
            H SS  +P A +K      +S      D  PR    S  +S+  SS + K  +   PSRR
Sbjct: 1381 HSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTP--SRERSSSASSPEMKDGLPRTPSRR 1438

Query: 251  GEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETPPTTQPSFTF 310
                + P           +      + SL   +  ++D     S   +E   + +P    
Sbjct: 1439 SRSGSSPG--------LRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALP 1490

Query: 311  TLPAAATASPPT-----SLLAP----------------STNPLLE-----SLKKMQTPPS 344
              P   + SP +       L P                +  PL +     S +++   PS
Sbjct: 1491 QTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPS 1550

Query: 345  LPPCPESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSK----PPTTLLGLI 400
              P   S   ++ ++ +  +TP       L Q    G   SP  DSK    P  +  G  
Sbjct: 1551 ASPQERSESDSSPDSKAKTRTP-------LRQRSRSG--SSPEVDSKSRLSPRRSRSGSS 1601

Query: 401  PAPSMVPATDTKAPPTLQAETATKPQATS-APSPAPKQSFLFGTQNTSPSSPAAPAASSA 459
            P     P    +A P  Q+ + + P+  + AP   P++S    +      SP   +++ +
Sbjct: 1602 PEVKDKP----RAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTES 1657

Query: 460  SPMFKPIFTAPPKSEKEGP-------TPP-------GPSVTATA------PSSSSLPTTT 499
            SP   P      +  +  P       TPP        P +T  A       S+SS P T 
Sbjct: 1658 SPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETR 1717

Query: 500  STTAPTFQPVFSSMGPPASVPLPA 523
            S T P  +       P  S P PA
Sbjct: 1718 SRTPPRHR-----RSPSVSSPEPA 1736



 Score = 38.1 bits (87), Expect = 0.041
 Identities = 53/221 (23%), Positives = 78/221 (35%), Gaps = 23/221 (10%)

Query: 411 TKAPPTLQAETATKPQATSAP--SPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFT 468
           T AP + +A  +T   + S+   S +  +S    T  T+ +  +   AS         F+
Sbjct: 252 TPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFS 311

Query: 469 APPKSEKEGPTPPGPSVTATAPSSSSLPTTT------STTAPTFQPVFSSMGPPASVPLP 522
            P  +  + P+ P    TAT   SS            S T P+  P  SS GP    P P
Sbjct: 312 EPGTTSTQRPSSPE---TATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEP--PAP 366

Query: 523 APFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSS 582
            P   +    +  P  T PL     +  S  +P    SP       P         SSSS
Sbjct: 367 TPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQ--------SSSS 418

Query: 583 VSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPP 623
            S+  S            +P++   +  PA GS  +    P
Sbjct: 419 ESSPPSPQPTKVSRHASSSPESPKPA--PAPGSHREISSSP 457



 Score = 32.3 bits (72), Expect = 2.3
 Identities = 54/225 (24%), Positives = 80/225 (35%), Gaps = 35/225 (15%)

Query: 548 SATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQASAA 607
           S ++  AP +  +  + SA   +      S S S+ + T +TA A   P           
Sbjct: 248 SRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSP----------- 296

Query: 608 SFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPAT 667
             +PA G   +   P + P TT     S   P++  TAT   ++ +          + AT
Sbjct: 297 --SPASGRRGEGDAPFSEPGTT-----STQRPSSPETATKQPSSPYEDKDKDKKEKS-AT 348

Query: 668 SSQPTLTFSNTS------TPTFNIPFGSS----AKSPLPSYPGANPQPAFGAAEGQPPGA 717
              P+   S+T       TP      G S    A +PL   P   P  A    +  PP +
Sbjct: 349 RPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKS 408

Query: 718 AKPALTPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVPAHVPTP 762
             P   P   SS     S+ P+P        AS+    P   P P
Sbjct: 409 --PEKLPQSSSS----ESSPPSPQPTKVSRHASSSPESPKPAPAP 447


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.306    0.121    0.344 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 47,792,482
Number of Sequences: 37866
Number of extensions: 3106478
Number of successful extensions: 48752
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 425
Number of HSP's successfully gapped in prelim test: 2240
Number of HSP's that attempted gapping in prelim test: 17299
Number of HSP's gapped (non-prelim): 14210
length of query: 987
length of database: 18,247,518
effective HSP length: 112
effective length of query: 875
effective length of database: 14,006,526
effective search space: 12255710250
effective search space used: 12255710250
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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