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Search of human proteins with 110347437
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|110347437 latent transforming growth factor beta binding
protein 4 isoform c [Homo sapiens]
(1557 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|110347437 latent transforming growth factor beta binding prot... 3460 0.0
gi|110347412 latent transforming growth factor beta binding prot... 3289 0.0
gi|110347431 latent transforming growth factor beta binding prot... 3289 0.0
gi|4557733 latent transforming growth factor beta binding protei... 1113 0.0
gi|46249414 latent transforming growth factor beta binding prote... 922 0.0
gi|46249412 latent transforming growth factor beta binding prote... 922 0.0
gi|194328809 latent transforming growth factor beta binding prot... 600 e-171
gi|56237021 fibrillin 3 precursor [Homo sapiens] 581 e-165
gi|18497288 latent transforming growth factor beta binding prote... 575 e-163
gi|24430141 fibrillin 1 precursor [Homo sapiens] 539 e-153
gi|66346695 fibrillin 2 precursor [Homo sapiens] 525 e-148
gi|134244285 Notch homolog 3 [Homo sapiens] 317 6e-86
gi|51873053 fibulin 2 isoform a precursor [Homo sapiens] 282 2e-75
gi|148833508 notch1 preproprotein [Homo sapiens] 279 1e-74
gi|24041035 notch 2 preproprotein [Homo sapiens] 268 2e-71
gi|51873055 fibulin 2 isoform b precursor [Homo sapiens] 265 2e-70
gi|55770876 notch4 preproprotein [Homo sapiens] 265 3e-70
gi|118572606 hemicentin 1 [Homo sapiens] 246 2e-64
gi|34734064 fibulin 1 isoform B precursor [Homo sapiens] 239 1e-62
gi|34734068 fibulin 1 isoform A precursor [Homo sapiens] 239 1e-62
gi|34734066 fibulin 1 isoform D [Homo sapiens] 239 1e-62
gi|34734062 fibulin 1 isoform C precursor [Homo sapiens] 239 1e-62
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 233 1e-60
gi|21704279 jagged 2 isoform b precursor [Homo sapiens] 225 2e-58
gi|21704277 jagged 2 isoform a precursor [Homo sapiens] 221 4e-57
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 214 4e-55
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 214 4e-55
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 214 4e-55
gi|122937283 6720455I24Rik homolog [Homo sapiens] 211 3e-54
gi|4557679 jagged 1 precursor [Homo sapiens] 202 3e-51
>gi|110347437 latent transforming growth factor beta binding protein 4
isoform c [Homo sapiens]
Length = 1557
Score = 3460 bits (8971), Expect = 0.0
Identities = 1557/1557 (100%), Positives = 1557/1557 (100%)
Query: 1 MAGGVRLLWVSLLVLLAQLGPQPGLGRLGERLRVRFTPVVCGLRCVHGPTGSRCTPTCAP 60
MAGGVRLLWVSLLVLLAQLGPQPGLGRLGERLRVRFTPVVCGLRCVHGPTGSRCTPTCAP
Sbjct: 1 MAGGVRLLWVSLLVLLAQLGPQPGLGRLGERLRVRFTPVVCGLRCVHGPTGSRCTPTCAP 60
Query: 61 RNATSVDSGAPGGAAPGGPGFRAFLCPLICHNGGVCVKPDRCLCPPDFAGKFCQLHSSGA 120
RNATSVDSGAPGGAAPGGPGFRAFLCPLICHNGGVCVKPDRCLCPPDFAGKFCQLHSSGA
Sbjct: 61 RNATSVDSGAPGGAAPGGPGFRAFLCPLICHNGGVCVKPDRCLCPPDFAGKFCQLHSSGA 120
Query: 121 RPPAPAVPGLTRSVYTMPLANHRDDEHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEA 180
RPPAPAVPGLTRSVYTMPLANHRDDEHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEA
Sbjct: 121 RPPAPAVPGLTRSVYTMPLANHRDDEHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEA 180
Query: 181 DAEAVARAEAAARAEAAAPYTVLAQSAPREDGYSDASGFGYCFRELRGGECASPLPGLRT 240
DAEAVARAEAAARAEAAAPYTVLAQSAPREDGYSDASGFGYCFRELRGGECASPLPGLRT
Sbjct: 181 DAEAVARAEAAARAEAAAPYTVLAQSAPREDGYSDASGFGYCFRELRGGECASPLPGLRT 240
Query: 241 QEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPTGFERVNGSCEDVDECATGGRC 300
QEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPTGFERVNGSCEDVDECATGGRC
Sbjct: 241 QEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPTGFERVNGSCEDVDECATGGRC 300
Query: 301 QHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNIT 360
QHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNIT
Sbjct: 301 QHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNIT 360
Query: 361 KQICCCSRVGKAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVS 420
KQICCCSRVGKAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVS
Sbjct: 361 KQICCCSRVGKAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVS 420
Query: 421 LSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSG 480
LSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSG
Sbjct: 421 LSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSG 480
Query: 481 MCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSP 540
MCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSP
Sbjct: 481 MCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSP 540
Query: 541 GSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGA 600
GSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGA
Sbjct: 541 GSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGA 600
Query: 601 SCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCD 660
SCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCD
Sbjct: 601 SCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCD 660
Query: 661 NTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNT 720
NTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNT
Sbjct: 661 NTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNT 720
Query: 721 AGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGP 780
AGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGP
Sbjct: 721 AGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGP 780
Query: 781 HGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAP 840
HGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAP
Sbjct: 781 HGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAP 840
Query: 841 GYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRE 900
GYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRE
Sbjct: 841 GYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRE 900
Query: 901 RGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPG 960
RGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPG
Sbjct: 901 RGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPG 960
Query: 961 SYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGR 1020
SYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGR
Sbjct: 961 SYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGR 1020
Query: 1021 HCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQP 1080
HCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQP
Sbjct: 1021 HCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQP 1080
Query: 1081 QAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECC 1140
QAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECC
Sbjct: 1081 QAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECC 1140
Query: 1141 CTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKS 1200
CTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKS
Sbjct: 1141 CTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKS 1200
Query: 1201 GVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPL 1260
GVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPL
Sbjct: 1201 GVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPL 1260
Query: 1261 VLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLYGEAWGMDC 1320
VLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLYGEAWGMDC
Sbjct: 1261 VLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLYGEAWGMDC 1320
Query: 1321 ALCPAQDSDDFEALCNVLRPPAYSPPRPGGFGLPYEYGPDLGPPYQGLPYGPELYPPPAL 1380
ALCPAQDSDDFEALCNVLRPPAYSPPRPGGFGLPYEYGPDLGPPYQGLPYGPELYPPPAL
Sbjct: 1321 ALCPAQDSDDFEALCNVLRPPAYSPPRPGGFGLPYEYGPDLGPPYQGLPYGPELYPPPAL 1380
Query: 1381 PYDPYPPPPGPFARREAPYGAPRFDMPDFEDDGGPYGESEAPAPPGPGTRWPYRSRDTRR 1440
PYDPYPPPPGPFARREAPYGAPRFDMPDFEDDGGPYGESEAPAPPGPGTRWPYRSRDTRR
Sbjct: 1381 PYDPYPPPPGPFARREAPYGAPRFDMPDFEDDGGPYGESEAPAPPGPGTRWPYRSRDTRR 1440
Query: 1441 SFPEPEEPPEGGSYAGSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDM 1500
SFPEPEEPPEGGSYAGSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDM
Sbjct: 1441 SFPEPEEPPEGGSYAGSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDM 1500
Query: 1501 TRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHCAPARPRA 1557
TRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHCAPARPRA
Sbjct: 1501 TRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHCAPARPRA 1557
>gi|110347412 latent transforming growth factor beta binding protein 4
isoform b [Homo sapiens]
Length = 1587
Score = 3289 bits (8527), Expect = 0.0
Identities = 1478/1488 (99%), Positives = 1478/1488 (99%), Gaps = 7/1488 (0%)
Query: 70 APGGAAPGGPGFRAFLCPLICHNGGVCVKPDRCLCPPDFAGKFCQLHSSGARPPAPAVPG 129
AP G AP LCPLICHNGGVCVKPDRCLCPPDFAGKFCQLHSSGARPPAPAVPG
Sbjct: 107 APAGKAP-------VLCPLICHNGGVCVKPDRCLCPPDFAGKFCQLHSSGARPPAPAVPG 159
Query: 130 LTRSVYTMPLANHRDDEHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAE 189
LTRSVYTMPLANHRDDEHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAE
Sbjct: 160 LTRSVYTMPLANHRDDEHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAE 219
Query: 190 AAARAEAAAPYTVLAQSAPREDGYSDASGFGYCFRELRGGECASPLPGLRTQEVCCRGAG 249
AAARAEAAAPYTVLAQSAPREDGYSDASGFGYCFRELRGGECASPLPGLRTQEVCCRGAG
Sbjct: 220 AAARAEAAAPYTVLAQSAPREDGYSDASGFGYCFRELRGGECASPLPGLRTQEVCCRGAG 279
Query: 250 LAWGVHDCQLCSERLGNSERVSAPDGPCPTGFERVNGSCEDVDECATGGRCQHGECANTR 309
LAWGVHDCQLCSERLGNSERVSAPDGPCPTGFERVNGSCEDVDECATGGRCQHGECANTR
Sbjct: 280 LAWGVHDCQLCSERLGNSERVSAPDGPCPTGFERVNGSCEDVDECATGGRCQHGECANTR 339
Query: 310 GGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRV 369
GGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRV
Sbjct: 340 GGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRV 399
Query: 370 GKAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPA 429
GKAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPA
Sbjct: 400 GKAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPA 459
Query: 430 TSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVC 489
TSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVC
Sbjct: 460 TSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVC 519
Query: 490 GPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGP 549
GPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGP
Sbjct: 520 GPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGP 579
Query: 550 GFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECT 609
GFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECT
Sbjct: 580 GFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECT 639
Query: 610 QSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCA 669
QSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCA
Sbjct: 640 QSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCA 699
Query: 670 CPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVD 729
CPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVD
Sbjct: 700 CPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVD 759
Query: 730 ECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEG 789
ECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEG
Sbjct: 760 ECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEG 819
Query: 790 SFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGA 849
SFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGA
Sbjct: 820 SFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGA 879
Query: 850 SCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQ 909
SCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQ
Sbjct: 880 SCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQ 939
Query: 910 RCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACD 969
RCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACD
Sbjct: 940 RCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACD 999
Query: 970 PGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECE 1029
PGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECE
Sbjct: 1000 PGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECE 1059
Query: 1030 TLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLP 1089
TLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLP
Sbjct: 1060 TLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLP 1119
Query: 1090 ARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGS 1149
ARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGS
Sbjct: 1120 ARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGS 1179
Query: 1150 GCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPG 1209
GCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPG
Sbjct: 1180 GCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPG 1239
Query: 1210 YSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRC 1269
YSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRC
Sbjct: 1240 YSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRC 1299
Query: 1270 VSNESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLYGEAWGMDCALCPAQDSD 1329
VSNESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLYGEAWGMDCALCPAQDSD
Sbjct: 1300 VSNESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLYGEAWGMDCALCPAQDSD 1359
Query: 1330 DFEALCNVLRPPAYSPPRPGGFGLPYEYGPDLGPPYQGLPYGPELYPPPALPYDPYPPPP 1389
DFEALCNVLRPPAYSPPRPGGFGLPYEYGPDLGPPYQGLPYGPELYPPPALPYDPYPPPP
Sbjct: 1360 DFEALCNVLRPPAYSPPRPGGFGLPYEYGPDLGPPYQGLPYGPELYPPPALPYDPYPPPP 1419
Query: 1390 GPFARREAPYGAPRFDMPDFEDDGGPYGESEAPAPPGPGTRWPYRSRDTRRSFPEPEEPP 1449
GPFARREAPYGAPRFDMPDFEDDGGPYGESEAPAPPGPGTRWPYRSRDTRRSFPEPEEPP
Sbjct: 1420 GPFARREAPYGAPRFDMPDFEDDGGPYGESEAPAPPGPGTRWPYRSRDTRRSFPEPEEPP 1479
Query: 1450 EGGSYAGSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDIN 1509
EGGSYAGSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDIN
Sbjct: 1480 EGGSYAGSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDIN 1539
Query: 1510 ECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHCAPARPRA 1557
ECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHCAPARPRA
Sbjct: 1540 ECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHCAPARPRA 1587
>gi|110347431 latent transforming growth factor beta binding protein 4
isoform a [Homo sapiens]
Length = 1624
Score = 3289 bits (8527), Expect = 0.0
Identities = 1478/1488 (99%), Positives = 1478/1488 (99%), Gaps = 7/1488 (0%)
Query: 70 APGGAAPGGPGFRAFLCPLICHNGGVCVKPDRCLCPPDFAGKFCQLHSSGARPPAPAVPG 129
AP G AP LCPLICHNGGVCVKPDRCLCPPDFAGKFCQLHSSGARPPAPAVPG
Sbjct: 144 APAGKAP-------VLCPLICHNGGVCVKPDRCLCPPDFAGKFCQLHSSGARPPAPAVPG 196
Query: 130 LTRSVYTMPLANHRDDEHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAE 189
LTRSVYTMPLANHRDDEHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAE
Sbjct: 197 LTRSVYTMPLANHRDDEHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAE 256
Query: 190 AAARAEAAAPYTVLAQSAPREDGYSDASGFGYCFRELRGGECASPLPGLRTQEVCCRGAG 249
AAARAEAAAPYTVLAQSAPREDGYSDASGFGYCFRELRGGECASPLPGLRTQEVCCRGAG
Sbjct: 257 AAARAEAAAPYTVLAQSAPREDGYSDASGFGYCFRELRGGECASPLPGLRTQEVCCRGAG 316
Query: 250 LAWGVHDCQLCSERLGNSERVSAPDGPCPTGFERVNGSCEDVDECATGGRCQHGECANTR 309
LAWGVHDCQLCSERLGNSERVSAPDGPCPTGFERVNGSCEDVDECATGGRCQHGECANTR
Sbjct: 317 LAWGVHDCQLCSERLGNSERVSAPDGPCPTGFERVNGSCEDVDECATGGRCQHGECANTR 376
Query: 310 GGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRV 369
GGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRV
Sbjct: 377 GGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRV 436
Query: 370 GKAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPA 429
GKAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPA
Sbjct: 437 GKAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPA 496
Query: 430 TSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVC 489
TSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVC
Sbjct: 497 TSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVC 556
Query: 490 GPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGP 549
GPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGP
Sbjct: 557 GPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGP 616
Query: 550 GFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECT 609
GFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECT
Sbjct: 617 GFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECT 676
Query: 610 QSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCA 669
QSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCA
Sbjct: 677 QSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCA 736
Query: 670 CPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVD 729
CPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVD
Sbjct: 737 CPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVD 796
Query: 730 ECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEG 789
ECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEG
Sbjct: 797 ECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEG 856
Query: 790 SFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGA 849
SFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGA
Sbjct: 857 SFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGA 916
Query: 850 SCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQ 909
SCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQ
Sbjct: 917 SCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQ 976
Query: 910 RCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACD 969
RCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACD
Sbjct: 977 RCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACD 1036
Query: 970 PGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECE 1029
PGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECE
Sbjct: 1037 PGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECE 1096
Query: 1030 TLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLP 1089
TLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLP
Sbjct: 1097 TLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLP 1156
Query: 1090 ARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGS 1149
ARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGS
Sbjct: 1157 ARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGS 1216
Query: 1150 GCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPG 1209
GCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPG
Sbjct: 1217 GCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPG 1276
Query: 1210 YSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRC 1269
YSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRC
Sbjct: 1277 YSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRC 1336
Query: 1270 VSNESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLYGEAWGMDCALCPAQDSD 1329
VSNESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLYGEAWGMDCALCPAQDSD
Sbjct: 1337 VSNESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLYGEAWGMDCALCPAQDSD 1396
Query: 1330 DFEALCNVLRPPAYSPPRPGGFGLPYEYGPDLGPPYQGLPYGPELYPPPALPYDPYPPPP 1389
DFEALCNVLRPPAYSPPRPGGFGLPYEYGPDLGPPYQGLPYGPELYPPPALPYDPYPPPP
Sbjct: 1397 DFEALCNVLRPPAYSPPRPGGFGLPYEYGPDLGPPYQGLPYGPELYPPPALPYDPYPPPP 1456
Query: 1390 GPFARREAPYGAPRFDMPDFEDDGGPYGESEAPAPPGPGTRWPYRSRDTRRSFPEPEEPP 1449
GPFARREAPYGAPRFDMPDFEDDGGPYGESEAPAPPGPGTRWPYRSRDTRRSFPEPEEPP
Sbjct: 1457 GPFARREAPYGAPRFDMPDFEDDGGPYGESEAPAPPGPGTRWPYRSRDTRRSFPEPEEPP 1516
Query: 1450 EGGSYAGSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDIN 1509
EGGSYAGSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDIN
Sbjct: 1517 EGGSYAGSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDIN 1576
Query: 1510 ECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHCAPARPRA 1557
ECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHCAPARPRA
Sbjct: 1577 ECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHCAPARPRA 1624
>gi|4557733 latent transforming growth factor beta binding protein 2
[Homo sapiens]
Length = 1821
Score = 1113 bits (2878), Expect = 0.0
Identities = 633/1586 (39%), Positives = 818/1586 (51%), Gaps = 182/1586 (11%)
Query: 30 ERLRVRFTPVVCGLRCVHGPTGSRCTPTCAPRNATSVDSGAPGGAAPGGPGFRAFLCPLI 89
+++++ FTP +C C G C +C + T++ S G P GFR + C +
Sbjct: 349 KKIKIVFTPTICKQTCARG----HCANSCERGDTTTLYSQGGHGHDPKS-GFRIYFCQIP 403
Query: 90 CHNGGVCVKPDRCLCPPDFAGKFCQLH---------SSGARPPAPAVPGLTRSVYTMPLA 140
C NGG C+ D C CP + GKFC L G+RP A L +S +T+PL+
Sbjct: 404 CLNGGRCIGRDECWCPANSTGKFCHLPIPQPDREPPGRGSRPRALLEAPLKQSTFTLPLS 463
Query: 141 NHRDDEHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAEAAA-------- 192
N + S+V VH+ HP EASV +HQV +V G EEA E
Sbjct: 464 NQLASVN--PSLVKVHIHHPPEASVQIHQVAQVRGGVEEALVENSVETRPPPWLPASPGH 521
Query: 193 --------RAEAAAPYTVLAQSAPREDGYSDASGFGYCFRELRGGECASPLPGLRTQEVC 244
A + P L +APR G G C+ G+CA+PL L TQE C
Sbjct: 522 SLWDSNNIPARSGEPPRPLPPAAPRPRGL-----LGRCYLNTVNGQCANPLLELTTQEDC 576
Query: 245 CRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPTGFERVNGS-CEDVDECATGGRCQHG 303
C G WGV C C R S + CP G++R+N + C+D++EC T G C+
Sbjct: 577 CGSVGAFWGVTLCAPCPPRPA-SPVIENGQLECPQGYKRLNLTHCQDINECLTLGLCKDA 635
Query: 304 ECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQI 363
EC NTRG Y C C G +LD SRS C+S IS +G C+R L G C+LP+ + ITKQI
Sbjct: 636 ECVNTRGSYLCTCRPGLMLDPSRSRCVSDKAISMLQGLCYRSLGPGTCTLPLAQRITKQI 695
Query: 364 CCCSRVGKAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQE----PPRV 419
CCCSRVGKAWG C+ CP G+E FREICPAG GY Y++SD+R + R +E PPR
Sbjct: 696 CCCSRVGKAWGSECEKCPLPGTEAFREICPAGHGYTYASSDIRLSMRKAEEEELARPPRE 755
Query: 420 SLSQPRTL---PATSRPSAGFLPTHRLEPRPEPRPDPRPGP-ELPLPSIPAW-TGPEIPE 474
+ PA +P T + D + G + PAW TG
Sbjct: 756 QGQRSSGALPGPAERQPLRVVTDTWLEAGTIPDKGDSQAGQVTTSVTHAPAWVTGNATTP 815
Query: 475 SGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRR-VPPPCAP 533
P G+ + + P + D LS G +D C C P
Sbjct: 816 PMPEQGIAEIQEEQVTP------------STDVLVTLSTPG-----IDRCAAGATNVCGP 858
Query: 534 GRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCD-LGRCENTPGSFLCVCPAG 592
G C N P +RCVC PG++ P A C D +EC R PC GRC N GS+ C C G
Sbjct: 859 GTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLR--DPCKGKGRCINRVGSYSCFCYPG 916
Query: 593 YQAAPHGAS--CQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGF---RGSACEEDVDEC 647
Y A GA+ CQD++EC Q PG+C G C N GS+ C C G+ R C+ D++EC
Sbjct: 917 YTLATSGATQECQDINECEQ-PGVCSGGQCTNTEGSYHCECDQGYIMVRKGHCQ-DINEC 974
Query: 648 AQEPPPCGPGRCDNTAGSFHC-ACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEG 706
+ P C GRC N+ GS+ C AC G+R G C DV+EC +P C +G+C N EG
Sbjct: 975 -RHPGTCPDGRCVNSPGSYTCLACEEGYR--GQSGSCVDVNECL-TPGVCAHGKCTNLEG 1030
Query: 707 SFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRG--R 764
SF+C C G++ + C+DVDEC + +CP C+N+ GSF C C +G+ ++
Sbjct: 1031 SFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLNTEGSFACSACENGYWVNEDGTA 1090
Query: 765 CTDVDECSSGAPPCGPHGHCTNTEGSFRCS-CAPGYRAPSGRPGPCADVNECLEGDFCFP 823
C D+DEC+ P P G CTNT GSF C C GYR PS C DV+EC +
Sbjct: 1091 CEDLDECAF--PGVCPSGVCTNTAGSFSCKDCDGGYR-PSPLGDSCEDVDECEDPQSSCL 1147
Query: 824 HGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQS-GICTNTDGSFECICPPG 882
GEC NT GS+ C C G++ G C DV+EC E+ C G C N+ GSF C+C PG
Sbjct: 1148 GGECKNTVGSYQCLCPQGFQLA-NGTVCEDVNECMGEEHCAPHGECLNSHGSFFCLCAPG 1206
Query: 883 HRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPE-GTCDDVDE 941
+ SC DVDEC P + G C N+ GS+ C+ C+ G+ PE G C D+DE
Sbjct: 1207 FVSAEGGTSCQDVDECATTDPCVGG--HCVNTEGSFNCL--CETGFQPSPESGECVDIDE 1262
Query: 942 CQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNL 1001
C++YG +CG +CEN+PGSYRC C PG+ P G C D+DEC N + CG+H C N
Sbjct: 1263 CEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNGDCIDIDECANDTMCGSHGFCDNT 1322
Query: 1002 PGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPM 1061
GSF+CLCDQG+E + G CVDVNECE + VCGAALCENVEGSFLC+C + EE+D
Sbjct: 1323 DGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGAALCENVEGSFLCLCASDLEEYDAQ 1382
Query: 1062 TGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTA 1121
G C PR + G S +AP PA R +CY
Sbjct: 1383 EGHC-RPRGAGGQ---SMSEAPTGDHAPAPT--------------------RMDCYSGQK 1418
Query: 1122 APDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSG-- 1179
C ++L RN T ECCCT G WG C + CP ++AE+ +CP G+GY+ G
Sbjct: 1419 GHAPCSSVLGRNTTQAECCCTQGASWGDACDL--CPSEDSAEFSEICPSGKGYIPVEGAW 1476
Query: 1180 --DLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEE 1237
++ D DEC +F +C +G C+NT PGY C C+ G++Y +C D+DEC D
Sbjct: 1477 TFGQTMYTDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDASHKKCEDHDECQDL- 1535
Query: 1238 PACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLD-----DNLGVCWQEVGADL 1292
ACE G CVNT GS+HC C PPL LD SQ+RC+++ S + D ++ +CW++V D
Sbjct: 1536 -ACENGECVNTEGSFHCFCSPPLTLDLSQQRCMNSTSSTEDLPDHDIHMDICWKKVTND- 1593
Query: 1293 VCSHPRLDRQATYTECCCLYGEAWGMDCALCPAQDSDDFEALCNVLRPPAYSPP----RP 1348
VCS P + TYTECCC GEAW CALCP + S+ + LCNV R A RP
Sbjct: 1594 VCSEPLRGHRTTYTECCCQDGEAWSQQCALCPPRSSEVYAQLCNVARIEAEREAGVHFRP 1653
Query: 1349 GGFGLPYEYGPDLGPPYQGLPYGPELYPPPALPYDPYPPPPGPFARREAPYGAPRFDMPD 1408
G YEYGP P L Y Y P PF P
Sbjct: 1654 G-----YEYGPG----------------PDDLHYSIYGPDGAPFYNYLGP---------- 1682
Query: 1409 FEDDGGPYGESEAPAPPGPGTRWPYRSRDTRRSFPEPEEPPE-GGSYAGSLAEP---YEE 1464
E P P P T S D P +P E Y S EP +E
Sbjct: 1683 ---------EDTVPEPAFPNTAG--HSADRTPILESPLQPSELQPHYVASHPEPPAGFEG 1731
Query: 1465 LEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1524
L+AEECGIL+GC NGRCVRV EG+TC CF+G++LD MACVD+NECD+ + LCV+
Sbjct: 1732 LQAEECGILNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHG 1791
Query: 1525 RCLNTDGSFRCICRPGFAPTHQPHHC 1550
C NT+GS+RC C PG+ P HC
Sbjct: 1792 YCENTEGSYRCHCSPGYVAEAGPPHC 1817
Score = 395 bits (1015), Expect = e-109
Identities = 294/907 (32%), Positives = 383/907 (42%), Gaps = 164/907 (18%)
Query: 480 GMCQ-----RNPQVCGPGRCISRPSGYTC-ACDSGFRLSPQGTRCIDVDECRRVPPPCAP 533
G CQ R+P C GRC++ P YTC AC+ G+R Q C+DV+EC P CA
Sbjct: 966 GHCQDINECRHPGTCPDGRCVNSPGSYTCLACEEGYR--GQSGSCVDVNECL-TPGVCAH 1022
Query: 534 GRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLC-VCPAG 592
G+C N GSFRC C G+ C DVDEC C G C NT GSF C C G
Sbjct: 1023 GKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECAS-RASCPTGLCLNTEGSFACSACENG 1081
Query: 593 YQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCV-CPAGFR----GSACEEDVDEC 647
Y G +C+D+DEC PG+C G C N GSF C C G+R G +CE DVDEC
Sbjct: 1082 YWVNEDGTACEDLDECA-FPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCE-DVDEC 1139
Query: 648 AQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGS 707
C G C NT GS+ C CP GF+ G C+DV+EC +G C N+ GS
Sbjct: 1140 EDPQSSCLGGECKNTVGSYQCLCPQGFQLAN-GTVCEDVNECMGEEHCAPHGECLNSHGS 1198
Query: 708 FQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHL--HRGRC 765
F C+C GF G+ C+DVDEC C G CVN+ GSF C C +G G C
Sbjct: 1199 FFCLCAPGFVSAEGGTSCQDVDECATTDPCVGGHCVNTEGSFNC-LCETGFQPSPESGEC 1257
Query: 766 TDVDECSS-GAPPCGPHGHCTNTEGSFRC--SCAPGYR-APSGRPGPCADVNECLEGDFC 821
D+DEC G P CG C N+ GS+RC C PG+ AP+G C D++EC C
Sbjct: 1258 VDIDECEDYGDPVCGTW-KCENSPGSYRCVLGCQPGFHMAPNG---DCIDIDECANDTMC 1313
Query: 822 FPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEE-DLCQSGICTNTDGSFECIC- 879
HG C NTDGSF C C G+ P G C+DV+EC +C + +C N +GSF C+C
Sbjct: 1314 GSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGAALCENVEGSFLCLCA 1373
Query: 880 --------------------------PPG-HRAGPDLASCLDVDECRERGPALCGSQRCE 912
P G H P C ++G A C S
Sbjct: 1374 SDLEEYDAQEGHCRPRGAGGQSMSEAPTGDHAPAPTRMDCYS----GQKGHAPCSSVLGR 1429
Query: 913 NSPGSYRCVRDCDPGYHAGPEGTCD----------------------------------- 937
N+ + C C G G CD
Sbjct: 1430 NTTQAECC---CTQGASWGD--ACDLCPSEDSAEFSEICPSGKGYIPVEGAWTFGQTMYT 1484
Query: 938 DVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQ-PTPGGGCQDVDECRNRSFCGAHA 996
D DEC +GP +C RC NT Y C C+PG+ C+D DEC++ + +
Sbjct: 1485 DADECVIFGPGLCPNGRCLNTVPGYVCL--CNPGFHYDASHKKCEDHDECQDLAC--ENG 1540
Query: 997 VCQNLPGSFQCLCDQGYEGARDGRHCV-------DVNECETLQGVCGAALCENVEGSFL- 1048
C N GSF C C + C+ D+ + + +C + +V L
Sbjct: 1541 ECVNTEGSFHCFCSPPLTLDLSQQRCMNSTSSTEDLPDHDIHMDICWKKVTNDVCSEPLR 1600
Query: 1049 --------CVCPNSPEEFDPMTGRCVPPRTS---AGTFPGSQPQAPASPVLPARPPPPPL 1097
C C + E + C PPR+S A ++ +A + RP
Sbjct: 1601 GHRTTYTECCCQDG-EAWSQQCALC-PPRSSEVYAQLCNVARIEAEREAGVHFRPGYE-- 1656
Query: 1098 PRRPSTPRQGPVGSGRRECYFDTAAPDACD--NILARNVTWQECCCTVGEGWGSGCRIQQ 1155
G G + ++ PD N L T E G + +
Sbjct: 1657 -----------YGPGPDDLHYSIYGPDGAPFYNYLGPEDTVPEPAFPNTAGHSA----DR 1701
Query: 1156 CPGTETAEYQS-LCPHGRGYLA-----PSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPG 1209
P E+ S L PH Y+A P+G L+ +EC + C++G CV G
Sbjct: 1702 TPILESPLQPSELQPH---YVASHPEPPAGFEGLQ--AEECGILNG--CENGRCVRVREG 1754
Query: 1210 YSCYCSNGYYYHTQRLECIDNDECAD-EEPA--CEGGRCVNTVGSYHCTCEPPLVLDGSQ 1266
Y+C C G+ + C+D +EC D PA C G C NT GSY C C P V +
Sbjct: 1755 YTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCENTEGSYRCHCSPGYVAEAGP 1814
Query: 1267 RRCVSNE 1273
C + E
Sbjct: 1815 PHCTAKE 1821
Score = 43.1 bits (100), Expect = 0.002
Identities = 48/186 (25%), Positives = 58/186 (31%), Gaps = 72/186 (38%)
Query: 946 GPEICGAQRCEN----TPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNL 1001
G +CG Q C ++ P C+P C+NR C +C
Sbjct: 165 GRNVCGGQCCPGWTTANSTNHCIKPVCEP--------------PCQNRGSCSRPQLC--- 207
Query: 1002 PGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPM 1061
+C G+ GAR CE V P+ EEFDP
Sbjct: 208 ------VCRSGFRGAR----------------------CEEV-------IPD--EEFDPQ 230
Query: 1062 TGRCVPPR-------------TSAGTFPGSQPQAPASPVLPARPPPPPLPRRPST-PRQG 1107
R P R GT +QP AP SP P PP L T P Q
Sbjct: 231 NSRLAPRRWAERSPNLRRSSAAGEGTLARAQPPAPQSPPAPQSPPAGTLSGLSQTHPSQQ 290
Query: 1108 PVGSGR 1113
VG R
Sbjct: 291 HVGLSR 296
Score = 41.2 bits (95), Expect = 0.008
Identities = 20/62 (32%), Positives = 30/62 (48%), Gaps = 6/62 (9%)
Query: 277 CPTGFE--RVNGSCEDVDEC----ATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCI 330
C GF+ + +C DV+EC C HG C NT G Y C C G++ ++ C
Sbjct: 1759 CFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYCENTEGSYRCHCSPGYVAEAGPPHCT 1818
Query: 331 SQ 332
++
Sbjct: 1819 AK 1820
Score = 36.2 bits (82), Expect = 0.25
Identities = 36/136 (26%), Positives = 48/136 (35%), Gaps = 24/136 (17%)
Query: 523 ECRRVPPPCAPGRC----ENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRC 578
+ RRV PP R + P P RA P PP GR
Sbjct: 111 QSRRVQPPAQTRRSTPLGQQQPA-------PRTRAAPALPRLGTPQRSGAAPPTPPRGRL 163
Query: 579 ENTPGSFLCVCPAGYQAAPHGASCQDVDECTQ---SPGLCGRGACKNLPGSFRCVCPAGF 635
G +C G Q P + + C + P RG+C CVC +GF
Sbjct: 164 T---GRNVC----GGQCCPGWTTANSTNHCIKPVCEPPCQNRGSCSRPQ---LCVCRSGF 213
Query: 636 RGSACEEDVDECAQEP 651
RG+ CEE + + +P
Sbjct: 214 RGARCEEVIPDEEFDP 229
Score = 32.3 bits (72), Expect = 3.7
Identities = 27/104 (25%), Positives = 36/104 (34%), Gaps = 9/104 (8%)
Query: 17 AQLGPQPGLGRLGERLRVRFTPVVCGLRCVHGPTGSRCTPTCAPRNATSVDSGAPGGAAP 76
AQ LG+ R R P + L P S P PR + + G P
Sbjct: 119 AQTRRSTPLGQQQPAPRTRAAPALPRLGT---PQRSGAAPPTPPRGRLTGRNVCGGQCCP 175
Query: 77 GGPGFRAF------LCPLICHNGGVCVKPDRCLCPPDFAGKFCQ 114
G + +C C N G C +P C+C F G C+
Sbjct: 176 GWTTANSTNHCIKPVCEPPCQNRGSCSRPQLCVCRSGFRGARCE 219
>gi|46249414 latent transforming growth factor beta binding protein 1
isoform LTBP-1L [Homo sapiens]
Length = 1722
Score = 922 bits (2383), Expect = 0.0
Identities = 526/1355 (38%), Positives = 703/1355 (51%), Gaps = 173/1355 (12%)
Query: 31 RLRVRFTPVVCGLRCVHGPTGSRCTPTCAPRNATSVDSGAPGGAAPG--GPGFRAFLCPL 88
R++V FTP +C + C G C +C N T++ S G AA FR +C L
Sbjct: 351 RIKVVFTPSICKVTCTKGS----CQNSCEKGNTTTLIS-ENGHAADTLTATNFRVVICHL 405
Query: 89 ICHNGGVCVKPDRCLCPPDFAGKFCQLHSSGARPPA----PAVPG------LTRSVYTMP 138
C NGG C D+C CPP+F GK CQ+ GA P PG + S +T+P
Sbjct: 406 PCMNGGQCSSRDKCQCPPNFTGKLCQIPVHGASVPKLYQHSQQPGKALGTHVIHSTHTLP 465
Query: 139 LANHRDDEHGVA-----SMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAEAAAR 193
L + GV ++V++HV+HP EASV +HQV R+ GP + EA +
Sbjct: 466 LTV--TSQQGVKVKFPPNIVNIHVKHPPEASVQIHQVSRIDGPTGQKTKEAQPGQSQVSY 523
Query: 194 AEAAAPYTVLAQSA-------PREDGYSDASGFGYCFRELRGGECASPLPGLRTQEVCCR 246
T S P + + G CF+E G +C LPGL QE CC
Sbjct: 524 QGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGSQCGKALPGLSKQEDCCG 583
Query: 247 GAGLAWGVHDCQLCSERL---GNSERVSAPDGPCPTGFERVNGS-CEDVDECATGGRCQH 302
G +WG + CQ C ++ G ++ + C G++RVN + C+D++EC G C +
Sbjct: 584 TVGTSWGFNKCQKCPKKPSYHGYNQMME-----CLPGYKRVNNTFCQDINECQLQGVCPN 638
Query: 303 GECANTRGGYTCVCPDGFLLDSSRSSCISQH-VISEAKGPCFRVLRDGG-CSLPILRNIT 360
GEC NT G Y C C GF D + SSC+ VISE KGPC+R++ G C P+ ++T
Sbjct: 639 GECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSGRQCMHPLSVHLT 698
Query: 361 KQICCCSRVGKAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVS 420
KQ+CCCS VGKAWG C+ CP G+ F+EICP G GY S R RP+ V
Sbjct: 699 KQLCCCS-VGKAWGPHCEKCPLPGTAAFKEICPGGMGYTVSGVHRR---RPIHHH---VG 751
Query: 421 LSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSG 480
P ++P A TH P P P E P+ ++ E GP G
Sbjct: 752 KGPVFVKPKNTQPVAK--STH---------PPPLPAKEEPVEALTFSR-----EHGP--G 793
Query: 481 MCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSP 540
+ + P + I PS +D ++ + PG+ + SP
Sbjct: 794 VAEPEVATAPPEKEI--PS-------------------LDQEKTK-----LEPGQPQLSP 827
Query: 541 GSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGA 600
G P F V E P P ++ +T + + P
Sbjct: 828 GISTIHLHPQFPG--------IVIEKTSPPVPVEVAPEASTSSASQVIAPT--------- 870
Query: 601 SCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEE---DVDECAQEPPPCGPG 657
+++ECT +P +CG G C NLP + C+C G+R S + D+DEC Q C G
Sbjct: 871 QVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQG 930
Query: 658 RCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQC-VCPMGF 716
RC+NT GSF C CPAGF + G C DVDEC R P C G C NT G+F+C C G+
Sbjct: 931 RCENTEGSFLCICPAGFMASEEGTNCIDVDECLR-PDVCGEGHCVNTVGAFRCEYCDSGY 989
Query: 717 QPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAP 776
+ G CED+DEC N CP ++CVNSPGS+QC C G G+C DVDEC P
Sbjct: 990 RMTQRG-RCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLE--P 1046
Query: 777 PCGPHGHCTNTEGSFRCSCAPGY-RAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFA 835
+G C+N EGS+ CSC GY R P + C D++EC +G+ C +G+C NT+GSF
Sbjct: 1047 NVCANGDCSNLEGSYMCSCHKGYTRTPDHKH--CRDIDECQQGNLCV-NGQCKNTEGSFR 1103
Query: 836 CTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDV 895
CTC GY+ C D+DEC LC G C NT+GSF+C+C G+RA C D+
Sbjct: 1104 CTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDI 1163
Query: 896 DECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQ-R 954
+EC E ++C C N+ GSY C C G+ TC D++EC+ P +CG Q
Sbjct: 1164 NECLE-DKSVCQRGDCINTAGSYDCT--CPDGFQLDDNKTCQDINECEH--PGLCGPQGE 1218
Query: 955 CENTPGSYRCTPACDPGYQPTPGGG-CQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGY 1013
C NT GS+ C C G+ + G C+D+DEC N + C +H C N GSF+CLC QG+
Sbjct: 1219 CLNTEGSFHCV--CQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGF 1276
Query: 1014 EGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAG 1073
+ +DG+ CVDVNECE L GVCG A CENVEGSFLCVC + +E+ PMTG+C ++
Sbjct: 1277 QAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDL 1336
Query: 1074 TFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARN 1133
QP+ ++ECY++ CDN+LA N
Sbjct: 1337 DVDVDQPKEE-----------------------------KKECYYNLNDASLCDNVLAPN 1367
Query: 1134 VTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLR------RDV 1187
VT QECCCT G GWG C I CP TAE+ +CP G+G++ P+G+ S +D
Sbjct: 1368 VTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFV-PAGESSSEAGGENYKDA 1426
Query: 1188 DECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVN 1247
DEC LF ++CK+G C+NT PGY CYC G YY +L+C D DEC D +C G+CVN
Sbjct: 1427 DECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPS-SCIDGQCVN 1485
Query: 1248 TVGSYHCTCEPPLVLDGSQRRCV----SNES-QSLDDNLGVCWQEVGADLVCSHPRLDRQ 1302
T GSY+C C P+VLD S++RC+ SNE + D +CW+ + + VCS P + +Q
Sbjct: 1486 TEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQ 1545
Query: 1303 ATYTECCCLYGEAWGMDCALCPAQDSDDFEALCNV 1337
TYTECCCLYGEAWGM CALCP +DSDD+ LCN+
Sbjct: 1546 TTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNI 1580
Score = 257 bits (657), Expect = 5e-68
Identities = 205/647 (31%), Positives = 265/647 (40%), Gaps = 110/647 (17%)
Query: 482 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPG 541
CQ+ +C G+C + + C C G++LS +C D+DEC+ CA G+C N+ G
Sbjct: 1084 CQQG-NLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQH-RHLCAHGQCRNTEG 1141
Query: 542 SFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGAS 601
SF+CVC G+RA C D++EC C G C NT GS+ C CP G+Q + +
Sbjct: 1142 SFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDN-KT 1200
Query: 602 CQDVDECTQSPGLCG-RGACKNLPGSFRCVCPAGFR----GSACEEDVDECAQEPPPCGP 656
CQD++EC + PGLCG +G C N GSF CVC GF G CE D+DEC
Sbjct: 1201 CQDINEC-EHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCE-DIDECVNNTVCDSH 1258
Query: 657 GRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVC---- 712
G CDNTAGSF C C GF++ G C DV+EC C CEN EGSF CVC
Sbjct: 1259 GFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADEN 1318
Query: 713 ----PMGFQ---------------PNTAGSEC----EDVDECENHLA--CPGQECVNSPG 747
PM Q P EC D C+N LA QEC + G
Sbjct: 1319 QEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSG 1378
Query: 748 S--------FQC---------RTCPSGH-HLHRGRCT---------DVDECSSGAPPCGP 780
+ F C CP G + G + D DEC
Sbjct: 1379 AGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICK 1438
Query: 781 HGHCTNTEGSFRCSCAPG-YRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCA 839
+G C NT + C C G Y P C D++EC + C G+C+NT+GS+ C C
Sbjct: 1439 NGFCLNTRPGYECYCKQGTYYDPVKLQ--CFDMDECQDPSSCID-GQCVNTEGSYNCFCT 1495
Query: 840 PGY----------RPGPRGASCLDVD--------ECSEEDLCQSGICTNTDGSFECICPP 881
RP + D S+E +C + EC C
Sbjct: 1496 HPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLY 1555
Query: 882 GHRAGPDLASC--LDVDECRERGPALCGSQRC-ENSPGSYRCVRDCDPGY--HAGPEGTC 936
G G A C D D+ + LC P + D Y A P
Sbjct: 1556 GEAWGMQCALCPLKDSDDYAQ----LCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQ 1611
Query: 937 DD-VDECQEYGPEICGAQ------RCENTPGSYRCTPACDPGYQ-PTPGGGCQDVDEC-- 986
D ++ +E E CG RC Y C C GY T C DV+EC
Sbjct: 1612 DRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCD--CFDGYHLDTAKMTCVDVNECDE 1669
Query: 987 -RNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQ 1032
NR +A C N GS++CLC GY + +C +N L+
Sbjct: 1670 LNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLNTALNLE 1716
Score = 153 bits (386), Expect = 1e-36
Identities = 127/463 (27%), Positives = 176/463 (38%), Gaps = 93/463 (20%)
Query: 1116 CYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYL 1175
C+ +T C L ++CC TVG WG + Q+CP P GY
Sbjct: 559 CFQETIGSQ-CGKALPGLSKQEDCCGTVGTSWGFN-KCQKCPKK---------PSYHGY- 606
Query: 1176 APSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECAD 1235
+ EC PGY C D +EC
Sbjct: 607 ---------NQMMEC----------------LPGYK---------RVNNTFCQDINEC-Q 631
Query: 1236 EEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCS 1295
+ C G C+NT+GSY CTC+ D + CV + + + G C++ V + C
Sbjct: 632 LQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVP-DPPVISEEKGPCYRLVSSGRQCM 690
Query: 1296 HPRLDRQATYTECCCLYGEAWGMDCALCPAQDSDDFEALCNVLRPPAYSPPRPGGFGL-- 1353
HP L T CCC G+AWG C CP + F+ +C PGG G
Sbjct: 691 HP-LSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEIC------------PGGMGYTV 737
Query: 1354 -------PYEYGPDLGP----PYQGLPYGPELYPPPALPYDPYPPPPGPFARREAPYGA- 1401
P + GP P P +PPP LP P F+R P A
Sbjct: 738 SGVHRRRPIHHHVGKGPVFVKPKNTQPVAKSTHPPP-LPAKEEPVEALTFSREHGPGVAE 796
Query: 1402 -------PRFDMPDFEDDGGPYGESEAPAPPGPGTRWPYRSRD----TRRSFPEPEE--P 1448
P ++P + + + PG T + + S P P E P
Sbjct: 797 PEVATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPGIVIEKTSPPVPVEVAP 856
Query: 1449 PEGGSYAGSLAEPYEELEAEECGIL-DGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVD 1507
S A + P + E EC + D C G C+ +P +TC C++GYR + CVD
Sbjct: 857 EASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVD 916
Query: 1508 INECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHC 1550
I+EC + + LC RC NT+GSF CIC GF + + +C
Sbjct: 917 IDECTQVQ---HLCSQGRCENTEGSFLCICPAGFMASEEGTNC 956
Score = 151 bits (381), Expect = 5e-36
Identities = 69/130 (53%), Positives = 86/130 (66%), Gaps = 4/130 (3%)
Query: 1425 PGPGTRWPYRSRDTRRSFPEPEEPPEGGSY--AGSLAEPYEELEAEECGILDGCTNGRCV 1482
P G R PY RD F E + PE Y +EEL+AEECGIL+GC NGRCV
Sbjct: 1581 PVTGRRQPY-GRDALVDFSE-QYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCV 1638
Query: 1483 RVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFA 1542
RV EG+TC CFDGY LD +M CVD+NECDE LC NA+C+NTDGS++C+C PG+
Sbjct: 1639 RVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYV 1698
Query: 1543 PTHQPHHCAP 1552
P+ +P++C P
Sbjct: 1699 PSDKPNYCTP 1708
Score = 110 bits (276), Expect = 8e-24
Identities = 84/308 (27%), Positives = 122/308 (39%), Gaps = 54/308 (17%)
Query: 279 TGFERVNGSCEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCI----SQHV 334
T ++ V C D+DEC C G+C NT G Y C C +LD+S CI S
Sbjct: 1457 TYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQ 1516
Query: 335 ISEA---KGPCFRVLRDGG-CSLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFRE 390
I E + C+ L D CS P++ T CC G+AWG C LCP S+ + +
Sbjct: 1517 IEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQ 1576
Query: 391 ICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPR 450
+C + +P G++ V S+ T P
Sbjct: 1577 LCNI---------PVTGRRQPYGRDA-LVDFSEQYT----------------------PE 1604
Query: 451 PDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFR 510
DP + L S + E G +G C GRC+ GYTC C G+
Sbjct: 1605 ADPYFIQDRFLNSFEEL---QAEECGILNG--------CENGRCVRVQEGYTCDCFDGYH 1653
Query: 511 LSPQGTRCIDVDECRRVPPP---CAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECH 567
L C+DV+EC + C +C N+ GS++C+C PG+ + C ++
Sbjct: 1654 LDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLNTAL 1713
Query: 568 RVPPPCDL 575
+ DL
Sbjct: 1714 NLEKDSDL 1721
Score = 69.7 bits (169), Expect = 2e-11
Identities = 30/85 (35%), Positives = 44/85 (51%), Gaps = 4/85 (4%)
Query: 1466 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNAR 1525
+ +EC + C NG+C F C C GY+L + C DI+EC LC + +
Sbjct: 1080 DIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRH----LCAHGQ 1135
Query: 1526 CLNTDGSFRCICRPGFAPTHQPHHC 1550
C NT+GSF+C+C G+ + HC
Sbjct: 1136 CRNTEGSFQCVCDQGYRASGLGDHC 1160
Score = 66.6 bits (161), Expect = 2e-10
Identities = 31/86 (36%), Positives = 42/86 (48%), Gaps = 4/86 (4%)
Query: 1465 LEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1524
L+ +EC + C NG C + + C C GY C DI+EC + LCVN
Sbjct: 1038 LDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGN----LCVNG 1093
Query: 1525 RCLNTDGSFRCICRPGFAPTHQPHHC 1550
+C NT+GSFRC C G+ + C
Sbjct: 1094 QCKNTEGSFRCTCGQGYQLSAAKDQC 1119
Score = 63.9 bits (154), Expect = 1e-09
Identities = 28/75 (37%), Positives = 39/75 (52%), Gaps = 4/75 (5%)
Query: 1476 CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRC 1535
C G C+ + C C DG++LD + C DINEC+ P CLNT+GSF C
Sbjct: 1173 CQRGDCINTAGSYDCTCPDGFQLDDNK-TCQDINECEHPGLCGP---QGECLNTEGSFHC 1228
Query: 1536 ICRPGFAPTHQPHHC 1550
+C+ GF+ + C
Sbjct: 1229 VCQQGFSISADGRTC 1243
Score = 62.0 bits (149), Expect = 4e-09
Identities = 29/91 (31%), Positives = 50/91 (54%), Gaps = 8/91 (8%)
Query: 1449 PEGGSYAGSLAEPYEELEAEECGIL--DGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACV 1506
P G S + + E Y++ A+EC + + C NG C+ G+ C C G D ++ C
Sbjct: 1410 PAGESSSEAGGENYKD--ADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCF 1467
Query: 1507 DINECDEAEAASPLCVNARCLNTDGSFRCIC 1537
D++EC + + C++ +C+NT+GS+ C C
Sbjct: 1468 DMDECQDPSS----CIDGQCVNTEGSYNCFC 1494
Score = 57.0 bits (136), Expect = 1e-07
Identities = 33/91 (36%), Positives = 43/91 (47%), Gaps = 4/91 (4%)
Query: 1451 GGSYAGSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINE 1510
G Y S A+ E + +EC C +G+C F C C GYR C DINE
Sbjct: 1107 GQGYQLSAAKDQCE-DIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINE 1165
Query: 1511 CDEAEAASPLCVNARCLNTDGSFRCICRPGF 1541
C E ++ +C C+NT GS+ C C GF
Sbjct: 1166 CLEDKS---VCQRGDCINTAGSYDCTCPDGF 1193
Score = 55.8 bits (133), Expect = 3e-07
Identities = 27/79 (34%), Positives = 36/79 (45%), Gaps = 10/79 (12%)
Query: 1466 EAEECGILDGCTN-------GRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAAS 1518
+ C +D C N G C F C C+ G++ CVD+NEC E S
Sbjct: 1239 DGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNEC---ELLS 1295
Query: 1519 PLCVNARCLNTDGSFRCIC 1537
+C A C N +GSF C+C
Sbjct: 1296 GVCGEAFCENVEGSFLCVC 1314
Score = 52.0 bits (123), Expect = 4e-06
Identities = 26/64 (40%), Positives = 31/64 (48%), Gaps = 5/64 (7%)
Query: 1492 CFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHCA 1551
C GY+ + C DINEC +C N CLNT GS+RC C+ GF P C
Sbjct: 612 CLPGYKR-VNNTFCQDINECQ----LQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCV 666
Query: 1552 PARP 1555
P P
Sbjct: 667 PDPP 670
Score = 50.8 bits (120), Expect = 1e-05
Identities = 28/79 (35%), Positives = 40/79 (50%), Gaps = 7/79 (8%)
Query: 1465 LEAEECGILDGCTNGRCVRVPEGFTCR-CFDGYRLDMTRMACVDINECDEAEAASPLCVN 1523
++ +EC D C G CV F C C GYR+ R C DI+EC C +
Sbjct: 957 IDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQ-RGRCEDIDECLNPST----CPD 1011
Query: 1524 ARCLNTDGSFRCI-CRPGF 1541
+C+N+ GS++C+ C GF
Sbjct: 1012 EQCVNSPGSYQCVPCTEGF 1030
Score = 48.5 bits (114), Expect = 5e-05
Identities = 29/107 (27%), Positives = 46/107 (42%), Gaps = 12/107 (11%)
Query: 1452 GSYAGSLAEPYEELEAEECGILDGCTN-------GRCVRVPEGFTCRCFDGYRLDMTRMA 1504
GSY + + ++ + + C ++ C + G C+ F C C G+ +
Sbjct: 1183 GSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRT 1242
Query: 1505 CVDINECDEAEAASPLC-VNARCLNTDGSFRCICRPGFAPTHQPHHC 1550
C DI+EC + +C + C NT GSFRC+C GF C
Sbjct: 1243 CEDIDEC----VNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGC 1285
Score = 48.5 bits (114), Expect = 5e-05
Identities = 36/134 (26%), Positives = 55/134 (41%), Gaps = 28/134 (20%)
Query: 231 CASPLPGLRTQEV-CCRGAGLAWGVHDCQLCS-------------------ERLGNSERV 270
C+ PL G +T CC G AWG+ C LC + G V
Sbjct: 1537 CSRPLVGKQTTYTECCCLYGEAWGMQ-CALCPLKDSDDYAQLCNIPVTGRRQPYGRDALV 1595
Query: 271 SAPDGPCPTGF-----ERVNGSCEDV--DECATGGRCQHGECANTRGGYTCVCPDGFLLD 323
+ P +R S E++ +EC C++G C + GYTC C DG+ LD
Sbjct: 1596 DFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLD 1655
Query: 324 SSRSSCISQHVISE 337
+++ +C+ + E
Sbjct: 1656 TAKMTCVDVNECDE 1669
Score = 46.2 bits (108), Expect = 2e-04
Identities = 26/80 (32%), Positives = 32/80 (40%), Gaps = 33/80 (41%)
Query: 40 VCGLRCVHG----PTGSRCT-PTCAPRNATSVDSGAPGGAAPGGPGFRAFLCPLICHNGG 94
VCG RC HG P RCT P+C P C NGG
Sbjct: 168 VCGGRCCHGWSKAPGSQRCTKPSCVPP----------------------------CQNGG 199
Query: 95 VCVKPDRCLCPPDFAGKFCQ 114
+C++P C+C P GK C+
Sbjct: 200 MCLRPQLCVCKPGTKGKACE 219
>gi|46249412 latent transforming growth factor beta binding protein 1
isoform LTBP-1S [Homo sapiens]
Length = 1396
Score = 922 bits (2383), Expect = 0.0
Identities = 526/1355 (38%), Positives = 703/1355 (51%), Gaps = 173/1355 (12%)
Query: 31 RLRVRFTPVVCGLRCVHGPTGSRCTPTCAPRNATSVDSGAPGGAAPG--GPGFRAFLCPL 88
R++V FTP +C + C G C +C N T++ S G AA FR +C L
Sbjct: 25 RIKVVFTPSICKVTCTKGS----CQNSCEKGNTTTLIS-ENGHAADTLTATNFRVVICHL 79
Query: 89 ICHNGGVCVKPDRCLCPPDFAGKFCQLHSSGARPPA----PAVPG------LTRSVYTMP 138
C NGG C D+C CPP+F GK CQ+ GA P PG + S +T+P
Sbjct: 80 PCMNGGQCSSRDKCQCPPNFTGKLCQIPVHGASVPKLYQHSQQPGKALGTHVIHSTHTLP 139
Query: 139 LANHRDDEHGVA-----SMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAEAAAR 193
L + GV ++V++HV+HP EASV +HQV R+ GP + EA +
Sbjct: 140 LTV--TSQQGVKVKFPPNIVNIHVKHPPEASVQIHQVSRIDGPTGQKTKEAQPGQSQVSY 197
Query: 194 AEAAAPYTVLAQSA-------PREDGYSDASGFGYCFRELRGGECASPLPGLRTQEVCCR 246
T S P + + G CF+E G +C LPGL QE CC
Sbjct: 198 QGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGSQCGKALPGLSKQEDCCG 257
Query: 247 GAGLAWGVHDCQLCSERL---GNSERVSAPDGPCPTGFERVNGS-CEDVDECATGGRCQH 302
G +WG + CQ C ++ G ++ + C G++RVN + C+D++EC G C +
Sbjct: 258 TVGTSWGFNKCQKCPKKPSYHGYNQMME-----CLPGYKRVNNTFCQDINECQLQGVCPN 312
Query: 303 GECANTRGGYTCVCPDGFLLDSSRSSCISQH-VISEAKGPCFRVLRDGG-CSLPILRNIT 360
GEC NT G Y C C GF D + SSC+ VISE KGPC+R++ G C P+ ++T
Sbjct: 313 GECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSGRQCMHPLSVHLT 372
Query: 361 KQICCCSRVGKAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVS 420
KQ+CCCS VGKAWG C+ CP G+ F+EICP G GY S R RP+ V
Sbjct: 373 KQLCCCS-VGKAWGPHCEKCPLPGTAAFKEICPGGMGYTVSGVHRR---RPIHHH---VG 425
Query: 421 LSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSG 480
P ++P A TH P P P E P+ ++ E GP G
Sbjct: 426 KGPVFVKPKNTQPVAK--STH---------PPPLPAKEEPVEALTFSR-----EHGP--G 467
Query: 481 MCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSP 540
+ + P + I PS +D ++ + PG+ + SP
Sbjct: 468 VAEPEVATAPPEKEI--PS-------------------LDQEKTK-----LEPGQPQLSP 501
Query: 541 GSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGA 600
G P F V E P P ++ +T + + P
Sbjct: 502 GISTIHLHPQFPG--------IVIEKTSPPVPVEVAPEASTSSASQVIAPT--------- 544
Query: 601 SCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEE---DVDECAQEPPPCGPG 657
+++ECT +P +CG G C NLP + C+C G+R S + D+DEC Q C G
Sbjct: 545 QVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQG 604
Query: 658 RCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQC-VCPMGF 716
RC+NT GSF C CPAGF + G C DVDEC R P C G C NT G+F+C C G+
Sbjct: 605 RCENTEGSFLCICPAGFMASEEGTNCIDVDECLR-PDVCGEGHCVNTVGAFRCEYCDSGY 663
Query: 717 QPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAP 776
+ G CED+DEC N CP ++CVNSPGS+QC C G G+C DVDEC P
Sbjct: 664 RMTQRG-RCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLE--P 720
Query: 777 PCGPHGHCTNTEGSFRCSCAPGY-RAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFA 835
+G C+N EGS+ CSC GY R P + C D++EC +G+ C +G+C NT+GSF
Sbjct: 721 NVCANGDCSNLEGSYMCSCHKGYTRTPDHKH--CRDIDECQQGNLCV-NGQCKNTEGSFR 777
Query: 836 CTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDV 895
CTC GY+ C D+DEC LC G C NT+GSF+C+C G+RA C D+
Sbjct: 778 CTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDI 837
Query: 896 DECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQ-R 954
+EC E ++C C N+ GSY C C G+ TC D++EC+ P +CG Q
Sbjct: 838 NECLE-DKSVCQRGDCINTAGSYDCT--CPDGFQLDDNKTCQDINECEH--PGLCGPQGE 892
Query: 955 CENTPGSYRCTPACDPGYQPTPGGG-CQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGY 1013
C NT GS+ C C G+ + G C+D+DEC N + C +H C N GSF+CLC QG+
Sbjct: 893 CLNTEGSFHCV--CQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGF 950
Query: 1014 EGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAG 1073
+ +DG+ CVDVNECE L GVCG A CENVEGSFLCVC + +E+ PMTG+C ++
Sbjct: 951 QAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDL 1010
Query: 1074 TFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARN 1133
QP+ ++ECY++ CDN+LA N
Sbjct: 1011 DVDVDQPKEE-----------------------------KKECYYNLNDASLCDNVLAPN 1041
Query: 1134 VTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLR------RDV 1187
VT QECCCT G GWG C I CP TAE+ +CP G+G++ P+G+ S +D
Sbjct: 1042 VTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFV-PAGESSSEAGGENYKDA 1100
Query: 1188 DECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVN 1247
DEC LF ++CK+G C+NT PGY CYC G YY +L+C D DEC D +C G+CVN
Sbjct: 1101 DECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPS-SCIDGQCVN 1159
Query: 1248 TVGSYHCTCEPPLVLDGSQRRCV----SNES-QSLDDNLGVCWQEVGADLVCSHPRLDRQ 1302
T GSY+C C P+VLD S++RC+ SNE + D +CW+ + + VCS P + +Q
Sbjct: 1160 TEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQ 1219
Query: 1303 ATYTECCCLYGEAWGMDCALCPAQDSDDFEALCNV 1337
TYTECCCLYGEAWGM CALCP +DSDD+ LCN+
Sbjct: 1220 TTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNI 1254
Score = 257 bits (657), Expect = 5e-68
Identities = 205/647 (31%), Positives = 265/647 (40%), Gaps = 110/647 (17%)
Query: 482 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPG 541
CQ+ +C G+C + + C C G++LS +C D+DEC+ CA G+C N+ G
Sbjct: 758 CQQG-NLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQH-RHLCAHGQCRNTEG 815
Query: 542 SFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGAS 601
SF+CVC G+RA C D++EC C G C NT GS+ C CP G+Q + +
Sbjct: 816 SFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDN-KT 874
Query: 602 CQDVDECTQSPGLCG-RGACKNLPGSFRCVCPAGFR----GSACEEDVDECAQEPPPCGP 656
CQD++EC + PGLCG +G C N GSF CVC GF G CE D+DEC
Sbjct: 875 CQDINEC-EHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCE-DIDECVNNTVCDSH 932
Query: 657 GRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVC---- 712
G CDNTAGSF C C GF++ G C DV+EC C CEN EGSF CVC
Sbjct: 933 GFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADEN 992
Query: 713 ----PMGFQ---------------PNTAGSEC----EDVDECENHLA--CPGQECVNSPG 747
PM Q P EC D C+N LA QEC + G
Sbjct: 993 QEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSG 1052
Query: 748 S--------FQC---------RTCPSGH-HLHRGRCT---------DVDECSSGAPPCGP 780
+ F C CP G + G + D DEC
Sbjct: 1053 AGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICK 1112
Query: 781 HGHCTNTEGSFRCSCAPG-YRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCA 839
+G C NT + C C G Y P C D++EC + C G+C+NT+GS+ C C
Sbjct: 1113 NGFCLNTRPGYECYCKQGTYYDPVKLQ--CFDMDECQDPSSCID-GQCVNTEGSYNCFCT 1169
Query: 840 PGY----------RPGPRGASCLDVD--------ECSEEDLCQSGICTNTDGSFECICPP 881
RP + D S+E +C + EC C
Sbjct: 1170 HPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLY 1229
Query: 882 GHRAGPDLASC--LDVDECRERGPALCGSQRC-ENSPGSYRCVRDCDPGY--HAGPEGTC 936
G G A C D D+ + LC P + D Y A P
Sbjct: 1230 GEAWGMQCALCPLKDSDDYAQ----LCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQ 1285
Query: 937 DD-VDECQEYGPEICGAQ------RCENTPGSYRCTPACDPGYQ-PTPGGGCQDVDEC-- 986
D ++ +E E CG RC Y C C GY T C DV+EC
Sbjct: 1286 DRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCD--CFDGYHLDTAKMTCVDVNECDE 1343
Query: 987 -RNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQ 1032
NR +A C N GS++CLC GY + +C +N L+
Sbjct: 1344 LNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLNTALNLE 1390
Score = 153 bits (386), Expect = 1e-36
Identities = 127/463 (27%), Positives = 176/463 (38%), Gaps = 93/463 (20%)
Query: 1116 CYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYL 1175
C+ +T C L ++CC TVG WG + Q+CP P GY
Sbjct: 233 CFQETIGSQ-CGKALPGLSKQEDCCGTVGTSWGFN-KCQKCPKK---------PSYHGY- 280
Query: 1176 APSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECAD 1235
+ EC PGY C D +EC
Sbjct: 281 ---------NQMMEC----------------LPGYK---------RVNNTFCQDINEC-Q 305
Query: 1236 EEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCS 1295
+ C G C+NT+GSY CTC+ D + CV + + + G C++ V + C
Sbjct: 306 LQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVP-DPPVISEEKGPCYRLVSSGRQCM 364
Query: 1296 HPRLDRQATYTECCCLYGEAWGMDCALCPAQDSDDFEALCNVLRPPAYSPPRPGGFGL-- 1353
HP L T CCC G+AWG C CP + F+ +C PGG G
Sbjct: 365 HP-LSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEIC------------PGGMGYTV 411
Query: 1354 -------PYEYGPDLGP----PYQGLPYGPELYPPPALPYDPYPPPPGPFARREAPYGA- 1401
P + GP P P +PPP LP P F+R P A
Sbjct: 412 SGVHRRRPIHHHVGKGPVFVKPKNTQPVAKSTHPPP-LPAKEEPVEALTFSREHGPGVAE 470
Query: 1402 -------PRFDMPDFEDDGGPYGESEAPAPPGPGTRWPYRSRD----TRRSFPEPEE--P 1448
P ++P + + + PG T + + S P P E P
Sbjct: 471 PEVATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPGIVIEKTSPPVPVEVAP 530
Query: 1449 PEGGSYAGSLAEPYEELEAEECGIL-DGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVD 1507
S A + P + E EC + D C G C+ +P +TC C++GYR + CVD
Sbjct: 531 EASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVD 590
Query: 1508 INECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHC 1550
I+EC + + LC RC NT+GSF CIC GF + + +C
Sbjct: 591 IDECTQVQ---HLCSQGRCENTEGSFLCICPAGFMASEEGTNC 630
Score = 151 bits (381), Expect = 5e-36
Identities = 69/130 (53%), Positives = 86/130 (66%), Gaps = 4/130 (3%)
Query: 1425 PGPGTRWPYRSRDTRRSFPEPEEPPEGGSY--AGSLAEPYEELEAEECGILDGCTNGRCV 1482
P G R PY RD F E + PE Y +EEL+AEECGIL+GC NGRCV
Sbjct: 1255 PVTGRRQPY-GRDALVDFSE-QYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCV 1312
Query: 1483 RVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFA 1542
RV EG+TC CFDGY LD +M CVD+NECDE LC NA+C+NTDGS++C+C PG+
Sbjct: 1313 RVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYV 1372
Query: 1543 PTHQPHHCAP 1552
P+ +P++C P
Sbjct: 1373 PSDKPNYCTP 1382
Score = 110 bits (276), Expect = 8e-24
Identities = 84/308 (27%), Positives = 122/308 (39%), Gaps = 54/308 (17%)
Query: 279 TGFERVNGSCEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCI----SQHV 334
T ++ V C D+DEC C G+C NT G Y C C +LD+S CI S
Sbjct: 1131 TYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQ 1190
Query: 335 ISEA---KGPCFRVLRDGG-CSLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFRE 390
I E + C+ L D CS P++ T CC G+AWG C LCP S+ + +
Sbjct: 1191 IEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQ 1250
Query: 391 ICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPR 450
+C + +P G++ V S+ T P
Sbjct: 1251 LCNI---------PVTGRRQPYGRDA-LVDFSEQYT----------------------PE 1278
Query: 451 PDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFR 510
DP + L S + E G +G C GRC+ GYTC C G+
Sbjct: 1279 ADPYFIQDRFLNSFEEL---QAEECGILNG--------CENGRCVRVQEGYTCDCFDGYH 1327
Query: 511 LSPQGTRCIDVDECRRVPPP---CAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECH 567
L C+DV+EC + C +C N+ GS++C+C PG+ + C ++
Sbjct: 1328 LDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLNTAL 1387
Query: 568 RVPPPCDL 575
+ DL
Sbjct: 1388 NLEKDSDL 1395
Score = 69.7 bits (169), Expect = 2e-11
Identities = 30/85 (35%), Positives = 44/85 (51%), Gaps = 4/85 (4%)
Query: 1466 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNAR 1525
+ +EC + C NG+C F C C GY+L + C DI+EC LC + +
Sbjct: 754 DIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRH----LCAHGQ 809
Query: 1526 CLNTDGSFRCICRPGFAPTHQPHHC 1550
C NT+GSF+C+C G+ + HC
Sbjct: 810 CRNTEGSFQCVCDQGYRASGLGDHC 834
Score = 66.6 bits (161), Expect = 2e-10
Identities = 31/86 (36%), Positives = 42/86 (48%), Gaps = 4/86 (4%)
Query: 1465 LEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1524
L+ +EC + C NG C + + C C GY C DI+EC + LCVN
Sbjct: 712 LDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGN----LCVNG 767
Query: 1525 RCLNTDGSFRCICRPGFAPTHQPHHC 1550
+C NT+GSFRC C G+ + C
Sbjct: 768 QCKNTEGSFRCTCGQGYQLSAAKDQC 793
Score = 63.9 bits (154), Expect = 1e-09
Identities = 28/75 (37%), Positives = 39/75 (52%), Gaps = 4/75 (5%)
Query: 1476 CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRC 1535
C G C+ + C C DG++LD + C DINEC+ P CLNT+GSF C
Sbjct: 847 CQRGDCINTAGSYDCTCPDGFQLDDNK-TCQDINECEHPGLCGP---QGECLNTEGSFHC 902
Query: 1536 ICRPGFAPTHQPHHC 1550
+C+ GF+ + C
Sbjct: 903 VCQQGFSISADGRTC 917
Score = 62.0 bits (149), Expect = 4e-09
Identities = 29/91 (31%), Positives = 50/91 (54%), Gaps = 8/91 (8%)
Query: 1449 PEGGSYAGSLAEPYEELEAEECGIL--DGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACV 1506
P G S + + E Y++ A+EC + + C NG C+ G+ C C G D ++ C
Sbjct: 1084 PAGESSSEAGGENYKD--ADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCF 1141
Query: 1507 DINECDEAEAASPLCVNARCLNTDGSFRCIC 1537
D++EC + + C++ +C+NT+GS+ C C
Sbjct: 1142 DMDECQDPSS----CIDGQCVNTEGSYNCFC 1168
Score = 57.0 bits (136), Expect = 1e-07
Identities = 33/91 (36%), Positives = 43/91 (47%), Gaps = 4/91 (4%)
Query: 1451 GGSYAGSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINE 1510
G Y S A+ E + +EC C +G+C F C C GYR C DINE
Sbjct: 781 GQGYQLSAAKDQCE-DIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINE 839
Query: 1511 CDEAEAASPLCVNARCLNTDGSFRCICRPGF 1541
C E ++ +C C+NT GS+ C C GF
Sbjct: 840 CLEDKS---VCQRGDCINTAGSYDCTCPDGF 867
Score = 55.8 bits (133), Expect = 3e-07
Identities = 27/79 (34%), Positives = 36/79 (45%), Gaps = 10/79 (12%)
Query: 1466 EAEECGILDGCTN-------GRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAAS 1518
+ C +D C N G C F C C+ G++ CVD+NEC E S
Sbjct: 913 DGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNEC---ELLS 969
Query: 1519 PLCVNARCLNTDGSFRCIC 1537
+C A C N +GSF C+C
Sbjct: 970 GVCGEAFCENVEGSFLCVC 988
Score = 52.0 bits (123), Expect = 4e-06
Identities = 26/64 (40%), Positives = 31/64 (48%), Gaps = 5/64 (7%)
Query: 1492 CFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHCA 1551
C GY+ + C DINEC +C N CLNT GS+RC C+ GF P C
Sbjct: 286 CLPGYKR-VNNTFCQDINECQ----LQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCV 340
Query: 1552 PARP 1555
P P
Sbjct: 341 PDPP 344
Score = 50.8 bits (120), Expect = 1e-05
Identities = 28/79 (35%), Positives = 40/79 (50%), Gaps = 7/79 (8%)
Query: 1465 LEAEECGILDGCTNGRCVRVPEGFTCR-CFDGYRLDMTRMACVDINECDEAEAASPLCVN 1523
++ +EC D C G CV F C C GYR+ R C DI+EC C +
Sbjct: 631 IDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQ-RGRCEDIDECLNPST----CPD 685
Query: 1524 ARCLNTDGSFRCI-CRPGF 1541
+C+N+ GS++C+ C GF
Sbjct: 686 EQCVNSPGSYQCVPCTEGF 704
Score = 48.5 bits (114), Expect = 5e-05
Identities = 29/107 (27%), Positives = 46/107 (42%), Gaps = 12/107 (11%)
Query: 1452 GSYAGSLAEPYEELEAEECGILDGCTN-------GRCVRVPEGFTCRCFDGYRLDMTRMA 1504
GSY + + ++ + + C ++ C + G C+ F C C G+ +
Sbjct: 857 GSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRT 916
Query: 1505 CVDINECDEAEAASPLC-VNARCLNTDGSFRCICRPGFAPTHQPHHC 1550
C DI+EC + +C + C NT GSFRC+C GF C
Sbjct: 917 CEDIDEC----VNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGC 959
Score = 48.5 bits (114), Expect = 5e-05
Identities = 36/134 (26%), Positives = 55/134 (41%), Gaps = 28/134 (20%)
Query: 231 CASPLPGLRTQEV-CCRGAGLAWGVHDCQLCS-------------------ERLGNSERV 270
C+ PL G +T CC G AWG+ C LC + G V
Sbjct: 1211 CSRPLVGKQTTYTECCCLYGEAWGMQ-CALCPLKDSDDYAQLCNIPVTGRRQPYGRDALV 1269
Query: 271 SAPDGPCPTGF-----ERVNGSCEDV--DECATGGRCQHGECANTRGGYTCVCPDGFLLD 323
+ P +R S E++ +EC C++G C + GYTC C DG+ LD
Sbjct: 1270 DFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLD 1329
Query: 324 SSRSSCISQHVISE 337
+++ +C+ + E
Sbjct: 1330 TAKMTCVDVNECDE 1343
>gi|194328809 latent transforming growth factor beta binding protein 3
isoform 1 [Homo sapiens]
Length = 1303
Score = 600 bits (1548), Expect = e-171
Identities = 446/1389 (32%), Positives = 591/1389 (42%), Gaps = 292/1389 (21%)
Query: 2 AGGVRLLWVSLLVLLAQLGPQPGLGRLGER------------LRVRFTPVVCGLRCVHGP 49
A G+ L + LL+LL LG + G GER +V F PV+C C+ G
Sbjct: 20 AAGLLALLLLLLLLLLGLGGRVEGGPAGERGAGGGGALARERFKVVFAPVICKRTCLKG- 78
Query: 50 TGSRCTPTCAP-RNATSVDSGAPGGAAPGGPGFRAFLCPLICHNGGVCVKPDRCLCPPDF 108
+C +C N T + G GFR +CPL C NGG C ++CLCPPDF
Sbjct: 79 ---QCRDSCQQGSNMTLIGENGHSTDTLTGSGFRVVVCPLPCMNGGQCSSRNQCLCPPDF 135
Query: 109 AGKFCQLHSSGAR---------------------------------------------PP 123
G+FCQ+ + GA PP
Sbjct: 136 TGRFCQVPAGGAGGGTGGSGPGLSRTGALSTGALPPLAPEGDSVASKHAIYAVQVIADPP 195
Query: 124 APAV-PGLTRSVYTMPLANHRDDEHGVAS--MVSVHVEHPQEASVVVHQVERVSGPWEEA 180
P P + + +PL + A +V+V V HP EASV VH++E
Sbjct: 196 GPGEGPPAQHAAFLVPLGPGQISAEVQAPPPVVNVRVHHPPEASVQVHRIES-------- 247
Query: 181 DAEAVARAEAAARAEAAAPYTVLAQSAPREDGYSDASGFGYCFRE-LRGGECAS-PLPGL 238
+ AE+AA ++ P+ + P G CF++ L C S PLPGL
Sbjct: 248 -----SNAESAAPSQHLLPHPKPSHPRPPTQ-----KPLGRCFQDTLPKQPCGSNPLPGL 297
Query: 239 RTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAP-----DGPCPTGFERVNGS-CEDVD 292
QE CC G AWG C C + + P CP G++R+N + C+D++
Sbjct: 298 TKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEVGADCPQGYKRLNSTHCQDIN 357
Query: 293 ECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLR-DGGC 351
ECA G C+HG+C N G Y CVCP G L SR+ CI+ E K CFR++ + C
Sbjct: 358 ECAMPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADK--PEEKSLCFRLVSPEHQC 415
Query: 352 SLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREICPAGPGYHY----------S 401
P+ +T+Q+CCCS VGKAWG CQ CP G+ F+EICPAG GYH
Sbjct: 416 QHPLTTRLTRQLCCCS-VGKAWGARCQRCPTDGTAAFKEICPAGKGYHILTSHQTLTIQG 474
Query: 402 ASDLRYNTRPLGQEPPRVSLSQPRTLP-----------ATSRPSAGFLPTHRLEPRPEPR 450
SD P G P+ P P T P + + P
Sbjct: 475 ESDFSLFLHPDGPPKPQQLPESPSQAPPPEDTEEERGVTTDSPVSEERSVQQSHPTATTT 534
Query: 451 PDPRPGPEL---PLPSIPAWTGPEIPESGPS----------SGMCQRNPQVCGPGRCISR 497
P RP PEL P P W P++P S + + C+ N +CG G C+
Sbjct: 535 P-ARPYPELISRPSPPTMRWFLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPG 593
Query: 498 PSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGR--CENSPGSFRCVCGPGFR--A 553
P Y+C C+ G+R PQ C+DV+EC PC PGR C N+ GS+ C C G+R
Sbjct: 594 PPDYSCHCNPGYRSHPQHRYCVDVNECE--AEPCGPGRGICMNTGGSYNCHCNRGYRLHV 651
Query: 554 GPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQ-AAPHGASCQDVDECTQSP 612
G C+D++EC + D G C N PG + C C GY+ A C+D+DEC + P
Sbjct: 652 GAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDEC-RDP 710
Query: 613 GLCGRGACKNLPGSFRCV-CPAGFR---GSACEEDVDECAQEPPPCGPGRCDNTAGSFHC 668
C G C+N PGSF+C+ C G+R G AC DV+ECA E PC PG C+N GSF C
Sbjct: 711 SSCPDGKCENKPGSFKCIACQPGYRSQGGGAC-RDVNECA-EGSPCSPGWCENLPGSFRC 768
Query: 669 ACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDV 728
C G+ G C DVDEC + C G C NT GSFQC C G+ + S CED+
Sbjct: 769 TCAQGYAPAPDGRSCLDVDEC-EAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDI 827
Query: 729 DECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGR-CTDVDECSSGAPPCGPHGHCTNT 787
DEC+ AC G +C+N+ GS++C CP GH L GR C D+DECS C PHG C N
Sbjct: 828 DECDFPAACIGGDCINTNGSYRC-LCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNL 886
Query: 788 EGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPH-GECLNTDGSFA-------CTCA 839
+GS+ C C G+ + G C +V + C+ + + + D A C C+
Sbjct: 887 QGSYVCVCDEGFTPTQDQHG-CEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCS 945
Query: 840 --------------PGYRPGPRGASC--------------------LDVDECS--EEDLC 863
P Y + C D+DEC ++C
Sbjct: 946 LGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEIC 1005
Query: 864 QSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRD 923
+ G C NT +EC C G +L C+DVDEC + + C + CEN+ G YRC
Sbjct: 1006 KEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDE--SNCRNGVCENTRGGYRCA-- 1061
Query: 924 CDPGYHAGP-EGTC-----DDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPG 977
C P P + C DVDECQ+ P C RC N PGSYRC C P + P P
Sbjct: 1062 CTPPAEYSPAQRQCLSPEEMDVDECQD--PAACRPGRCVNLPGSYRC--ECRPPWVPGPS 1117
Query: 978 GGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGA 1037
G + E VC + G +C G + ++C QG
Sbjct: 1118 GRDCQLPESPAERAPERRDVCWSQRGE-DGMCAGPLAGP-----ALTFDDCCCRQGRGWG 1171
Query: 1038 ALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQA----PASPVLPARPP 1093
A C R PPR + P SQ ++ SP+L +PP
Sbjct: 1172 AQC-----------------------RPCPPRGAGSHCPTSQSESNSFWDTSPLLLGKPP 1208
Query: 1094 PPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRI 1153
R E D++ D+ EC C G R
Sbjct: 1209 -------------------RDE---DSSEEDS-----------DECRCVSG-------RC 1228
Query: 1154 QQCPGTETAEYQSLCPHGRGYLAPSGDLSLRR--DVDECQLF--RDQVCKSGVCVNTAPG 1209
PG E CP G D S R D+DEC+ R +CKS CVNT+
Sbjct: 1229 VPRPGGAVCE----CPGGFQL-----DASRARCVDIDECRELNQRGLLCKSERCVNTSGS 1279
Query: 1210 YSCYCSNGY 1218
+ C C G+
Sbjct: 1280 FRCVCKAGF 1288
Score = 502 bits (1292), Expect = e-141
Identities = 368/1103 (33%), Positives = 469/1103 (42%), Gaps = 225/1103 (20%)
Query: 565 ECHRVPPPCDLGRCENTP--GSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKN 622
+CH+ P G + P G CP GY+ + CQD++EC PG+C G C N
Sbjct: 315 KCHKCPQLQYTGVQKPGPVRGEVGADCPQGYKRL-NSTHCQDINECAM-PGVCRHGDCLN 372
Query: 623 LPGSFRCVCPAGFR----GSACEEDVDE----CAQEPPP------------------CGP 656
PGS+RCVCP G + C D E C + P C
Sbjct: 373 NPGSYRCVCPPGHSLGPSRTQCIADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSV 432
Query: 657 G--------RC--DNTAGSFHCACPAG-----------------------FRSRGPGAPC 683
G RC D TA +F CPAG GP P
Sbjct: 433 GKAWGARCQRCPTDGTA-AFKEICPAGKGYHILTSHQTLTIQGESDFSLFLHPDGPPKPQ 491
Query: 684 QDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHL----ACPG 739
Q + +++PPP E+TE G ++ SE V + A P
Sbjct: 492 QLPESPSQAPPP------EDTEEE------RGVTTDSPVSEERSVQQSHPTATTTPARPY 539
Query: 740 QECVNSPGSFQCR-------TCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFR 792
E ++ P R S + + T+ DEC CG HG C +
Sbjct: 540 PELISRPSPPTMRWFLPDLPPSRSAVEIAPTQVTETDECRLNQNICG-HGECVPGPPDYS 598
Query: 793 CSCAPGYRA-PSGRPGPCADVNECLEGDFCFP-HGECLNTDGSFACTCAPGYR--PGPRG 848
C C PGYR+ P R C DVNEC E + C P G C+NT GS+ C C GYR G G
Sbjct: 599 CHCNPGYRSHPQHRY--CVDVNEC-EAEPCGPGRGICMNTGGSYNCHCNRGYRLHVGAGG 655
Query: 849 ASCLDVDECSEEDLC-QSGICTNTDGSFECICPPGHRAGPDLAS-CLDVDECRERGPALC 906
SC+D++EC++ LC G C N G ++C C PG+R C D+DECR+ P+ C
Sbjct: 656 RSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRD--PSSC 713
Query: 907 GSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTP 966
+CEN PGS++C+ C PGY + G C DV+EC E P C CEN PGS+RCT
Sbjct: 714 PDGKCENKPGSFKCIA-CQPGYRSQGGGACRDVNECAEGSP--CSPGWCENLPGSFRCT- 769
Query: 967 ACDPGYQPTPGG-GCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDV 1025
C GY P P G C DVDEC C + +C N PGSFQC C GY +RD HC D+
Sbjct: 770 -CAQGYAPAPDGRSCLDVDECEAGDVCD-NGICSNTPGSFQCQCLSGYHLSRDRSHCEDI 827
Query: 1026 NECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQA--- 1082
+EC+ C C N GS+ C+CP R V R SQ +
Sbjct: 828 DECD-FPAACIGGDCINTNGSYRCLCPQGH--------RLVGGRKCQDIDECSQDPSLCL 878
Query: 1083 PASPVLPARPPPPPLPRRPSTPRQGPVGSG-------RRECYFDTAAPDACDNILARNVT 1135
P + + TP Q G ++ECY + CD++LA NVT
Sbjct: 879 PHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVT 938
Query: 1136 WQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSG----DLSLRRDVDECQ 1191
QECCC++G GWG C I CP +AE+ SLCP G+GY + + RD+DEC
Sbjct: 939 QQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECM 998
Query: 1192 LFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGS 1251
LF ++CK G CVNT PGY CYC G+YY LEC+D DEC DE C G C NT G
Sbjct: 999 LFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESN-CRNGVCENTRGG 1057
Query: 1252 YHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCL 1311
Y C C PP +QR+C+S E +D EC
Sbjct: 1058 YRCACTPPAEYSPAQRQCLSPEEMDVD----------------------------EC--- 1086
Query: 1312 YGEAWGMDCALCPAQDSDDFEALCNVLRPPAYSPPRPGG-FGLPYEYGPDLGPPYQGLPY 1370
D A C RPG LP Y + PP+ P
Sbjct: 1087 ------QDPAAC-----------------------RPGRCVNLPGSYRCECRPPWVPGPS 1117
Query: 1371 GPELYPPPALPYDPYPPPP----------GPFARREAPYGAPRFDMPDFE-DDGGPYGES 1419
G + LP P P G P P D G +G
Sbjct: 1118 GRDCQ----LPESPAERAPERRDVCWSQRGEDGMCAGPLAGPALTFDDCCCRQGRGWGAQ 1173
Query: 1420 EAPAPP-GPGTRWPYRSRDTRRSFPEPE-----EPPEGGSYAGSLAEPYEELEAEECGIL 1473
P PP G G+ P S+ SF + +PP E E +++EC
Sbjct: 1174 CRPCPPRGAGSHCP-TSQSESNSFWDTSPLLLGKPPRD--------EDSSEEDSDECR-- 1222
Query: 1474 DGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSF 1533
C +GRCV P G C C G++LD +R CVDI+EC E LC + RC+NT GSF
Sbjct: 1223 --CVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSF 1280
Query: 1534 RCICRPGFAPTHQPHHCAPARPR 1556
RC+C+ GFA + C P R R
Sbjct: 1281 RCVCKAGFARSRPHGACVPQRRR 1303
Score = 337 bits (863), Expect = 7e-92
Identities = 233/658 (35%), Positives = 296/658 (44%), Gaps = 97/658 (14%)
Query: 486 PQVCGPGR-CISRPSGYTCACDSGFRL-SPQGTRCIDVDECRRVPPPCAPGRCENSPGSF 543
P +CG G CI+ P Y C C G+RL + + C D+DECR P C G+CEN PGSF
Sbjct: 667 PHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRD-PSSCPDGKCENKPGSF 725
Query: 544 RCV-CGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASC 602
+C+ C PG+R+ A C DV+EC PC G CEN PGSF C C GY AP G SC
Sbjct: 726 KCIACQPGYRSQGGGA-CRDVNECAE-GSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSC 783
Query: 603 QDVDECTQSPGLCGRGACKNLPGSFRCVCPAGF---RGSACEEDVDECAQEPPPCGPGRC 659
DVDEC ++ +C G C N PGSF+C C +G+ R + ED+DEC P C G C
Sbjct: 784 LDVDEC-EAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDEC-DFPAACIGGDC 841
Query: 660 DNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCT-YGRCENTEGSFQCVCPMGFQP 718
NT GS+ C CP G R G G CQD+DEC++ P C +G C+N +GS+ CVC GF P
Sbjct: 842 INTNGSYRCLCPQGHRLVG-GRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTP 900
Query: 719 NTAGSECEDVDE----------------CENHLAC--PGQECVNSPGS--------FQCR 752
CE+V++ C++ LA QEC S G+ + C
Sbjct: 901 TQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCP 960
Query: 753 T---------CPSGHHLHRGRCT---------DVDECSSGAPPCGPHGHCTNTEGSFRCS 794
CP G + D+DEC G C NT+ + C
Sbjct: 961 VYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECY 1020
Query: 795 CAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCL-- 852
C G+ G C DV+ECL+ C +G C NT G + C C P P CL
Sbjct: 1021 CKQGFYY-DGNLLECVDVDECLDESNC-RNGVCENTRGGYRCACTPPAEYSPAQRQCLSP 1078
Query: 853 ---DVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPA---LC 906
DVDEC + C+ G C N GS+ C C P GP C + ER P +C
Sbjct: 1079 EEMDVDECQDPAACRPGRCVNLPGSYRCECRPPWVPGPSGRDCQLPESPAERAPERRDVC 1138
Query: 907 GSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDV---------DECQEYGPEICGAQ--RC 955
SQR E+ C G AGP T DD +C+ P G+
Sbjct: 1139 WSQRGEDG----MCA-----GPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSHCPTS 1189
Query: 956 ENTPGSYRCTPACDPGYQPTPGGGC-QDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYE 1014
++ S+ T G P +D DECR S C PG C C G++
Sbjct: 1190 QSESNSFWDTSPLLLGKPPRDEDSSEEDSDECRCVS-----GRCVPRPGGAVCECPGGFQ 1244
Query: 1015 GARDGRHCVDVNECETLQG---VCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPR 1069
CVD++EC L +C + C N GSF CVC P G CVP R
Sbjct: 1245 LDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRP-HGACVPQR 1301
Score = 130 bits (328), Expect = 8e-30
Identities = 129/469 (27%), Positives = 174/469 (37%), Gaps = 103/469 (21%)
Query: 1094 PPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCC-TVGEGWG-SGC 1151
P P P P P Q P+G C+ DT C + +T QE CC ++G WG S C
Sbjct: 261 PHPKPSHPRPPTQKPLG----RCFQDTLPKQPCGSNPLPGLTKQEDCCGSIGTAWGQSKC 316
Query: 1152 ----RIQ----QCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVC 1203
++Q Q PG E + CP G L + + +D++EC + VC+ G C
Sbjct: 317 HKCPQLQYTGVQKPGPVRGEVGADCPQGYKRL----NSTHCQDINECAM--PGVCRHGDC 370
Query: 1204 VNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLD 1263
+N Y C C G+ R +CI AD+
Sbjct: 371 LNNPGSYRCVCPPGHSLGPSRTQCI-----ADKP-------------------------- 399
Query: 1264 GSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLYGEAWGMDCALC 1323
E +SL C++ V + C HP L + T CCC G+AWG C C
Sbjct: 400 ---------EEKSL------CFRLVSPEHQCQHP-LTTRLTRQLCCCSVGKAWGARCQRC 443
Query: 1324 PAQDSDDFEALCNV-----LRPPAYSPPRPGGFGLPYEYGPDLGPPYQGLPYGPELYPPP 1378
P + F+ +C + + G PD P Q LP P PPP
Sbjct: 444 PTDGTAAFKEICPAGKGYHILTSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSQAPPP 503
Query: 1379 ALPYDPYPPPPGPFARREAPYGAPRFDMPDFEDDGGPYGESEAPAPPGPGTRWPYRSRDT 1438
E G D P E+ A P PY +
Sbjct: 504 --------------EDTEEERGVTT-DSPVSEERSVQQSHPTATTTPAR----PYPELIS 544
Query: 1439 RRSFPE-----PEEPPEGGSYAGSLAEPYEELEAEECGILDG-CTNGRCVRVPEGFTCRC 1492
R S P P+ PP S + P + E +EC + C +G CV P ++C C
Sbjct: 545 RPSPPTMRWFLPDLPP---SRSAVEIAPTQVTETDECRLNQNICGHGECVPGPPDYSCHC 601
Query: 1493 FDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGF 1541
GYR CVD+NEC EAE P C+NT GS+ C C G+
Sbjct: 602 NPGYRSHPQHRYCVDVNEC-EAEPCGP--GRGICMNTGGSYNCHCNRGY 647
Score = 60.8 bits (146), Expect = 1e-08
Identities = 56/176 (31%), Positives = 63/176 (35%), Gaps = 44/176 (25%)
Query: 229 GECASPL--PGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPTGFERVNG 286
G CA PL P L + CCR G WG C+ C R S CPT N
Sbjct: 1146 GMCAGPLAGPALTFDDCCCR-QGRGWGAQ-CRPCPPRGAGSH--------CPTSQSESNS 1195
Query: 287 ------------------SCEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSS 328
S ED DEC RC G C GG C CP GF LD+SR+
Sbjct: 1196 FWDTSPLLLGKPPRDEDSSEEDSDEC----RCVSGRCVPRPGGAVCECPGGFQLDASRAR 1251
Query: 329 CISQHVISEAKGPCFRVLRDGG--CSLPILRNITKQICCCSRVGKAWGRGCQLCPP 382
C+ I E R L G C N + C + G A R C P
Sbjct: 1252 CVD---IDEC-----RELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGACVP 1299
Score = 52.4 bits (124), Expect = 3e-06
Identities = 63/219 (28%), Positives = 82/219 (37%), Gaps = 36/219 (16%)
Query: 1358 GPDLGPPYQG----LPYGPELY------PPPALPYDPYPPPPGPFARREAPYGAPRFDMP 1407
GP GPP Q +P GP PPP + + PP EA R +
Sbjct: 196 GPGEGPPAQHAAFLVPLGPGQISAEVQAPPPVVNVRVHHPP-------EASVQVHRIESS 248
Query: 1408 DFEDDGGPYGESEAPAP--PGPGTRWPYRS--RDTRRSFPEPEEPPEG----GSYAGSLA 1459
+ E P P P P T+ P +DT P P G GS+
Sbjct: 249 NAESAAPSQHLLPHPKPSHPRPPTQKPLGRCFQDTLPKQPCGSNPLPGLTKQEDCCGSIG 308
Query: 1460 EPYEELEAEECGILD--GCTNGRCVRVPEGFTCRCFDGY-RLDMTRMACVDINECDEAEA 1516
+ + + +C L G VR G C GY RL+ T C DINEC A
Sbjct: 309 TAWGQSKCHKCPQLQYTGVQKPGPVRGEVGADCP--QGYKRLNSTH--CQDINEC----A 360
Query: 1517 ASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHCAPARP 1555
+C + CLN GS+RC+C PG + C +P
Sbjct: 361 MPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADKP 399
>gi|56237021 fibrillin 3 precursor [Homo sapiens]
Length = 2809
Score = 581 bits (1497), Expect = e-165
Identities = 438/1395 (31%), Positives = 568/1395 (40%), Gaps = 205/1395 (14%)
Query: 222 CFRELRGGECASPLPGLRTQ-EVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPTG 280
C+ + G CA P PG T+ E CC +G CQLC + +S A C +G
Sbjct: 620 CYGAIEKGSCARPFPGTVTKSECCCANPDHGFG-EPCQLCPAK--DSAEFQAL---CSSG 673
Query: 281 FERVNGSCEDVDECATGGR-CQHGECANTRGGYTCVCPDGFLLDSSRSSC--ISQHVISE 337
+ D++ECA C +G C N RG Y CVC G+ +S C + + ++
Sbjct: 674 LG-ITTDGRDINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNS 732
Query: 338 A---KGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQ--LCPPFGSEGFREIC 392
G C CS P + + C V + C +C C
Sbjct: 733 LLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSPCVSGVCRNLAGS---YTC 789
Query: 393 PAGPGYHYSAS-----DLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRP 447
GPG S D T L + R ++ L S S P
Sbjct: 790 KCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVN----LQGASLRSECCATLGAAWGSP 845
Query: 448 EPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDS 507
R + P + T ++ E C+ P VC GRC++ + C C
Sbjct: 846 CERCEIDPACARGFARMTGVTCDDVNE-------CESFPGVCPNGRCVNTAGSFRCECPE 898
Query: 508 GFRLSPQGTRCIDV-----------DECRRVPPP--------CAPG-----RCENSPG-- 541
G L G C+DV DEC P C+ G CE P
Sbjct: 899 GLMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVWGVECEACPDPE 958
Query: 542 --SFRCVCGPGFRAGPR-----AAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQ 594
F +C G R DV+EC P C G C NT GSF C C G+
Sbjct: 959 SLEFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFA 1018
Query: 595 AAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEE----DVDECAQE 650
+C D+DEC SP LCG+G C N PGSF C C G+ DVDECA++
Sbjct: 1019 LDAQERNCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARD 1078
Query: 651 PPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQC 710
P C G C NT GS+ C CP G G C+D+DEC+ S C +G+C N G+FQC
Sbjct: 1079 PLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQC 1138
Query: 711 VCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHR-GR-CTDV 768
C GFQ C D++EC C+N+ GS++C +C G+ L GR C DV
Sbjct: 1139 SCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRC-SCGQGYSLMPDGRACADV 1197
Query: 769 DECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRA-PSGRPGPCADVNEC-LEGDFCFPHGE 826
DEC C GHCTN G RC C G+ A P R C DV+EC L C HG+
Sbjct: 1198 DECEENPRVCD-QGHCTNMPGGHRCLCYDGFMATPDMRT--CVDVDECDLNPHICL-HGD 1253
Query: 827 CLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDL-CQS-GICTNTDGSFECICPPGHR 884
C NT GSF C C GY C DVDEC C S C N GSF C C PG
Sbjct: 1254 CENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWV 1313
Query: 885 AGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQE 944
D C D+DEC + C N PGSYRC C G+ AG C+D DEC E
Sbjct: 1314 G--DGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCT--CRQGF-AGDGFFCEDRDECAE 1368
Query: 945 YGPEICGAQRCENTPGSYRCTPACDPGYQPTPGG-GCQDVDECRNRSFCGAHAVCQNLPG 1003
++C +C N PG YRC C+ G+ PT CQDVDEC + C A C+NLPG
Sbjct: 1369 -NVDLCDNGQCLNAPGGYRCE--CEMGFDPTEDHRACQDVDECAQGNLC-AFGSCENLPG 1424
Query: 1004 SFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTG 1063
F+C+C+ GYE R G +C D+NEC C +C N GS+LC CP E +P
Sbjct: 1425 MFRCICNGGYELDRGGGNCTDINECADPVN-CINGVCINTPGSYLCSCPQD-FELNPSGV 1482
Query: 1064 RCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTA-- 1121
CV R C+ +T
Sbjct: 1483 GCVDTRAG-------------------------------------------NCFLETHDR 1499
Query: 1122 --APDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSG 1179
+ +C + VT CCC++G WG+ C + CP T EY++LCP G G+ P+
Sbjct: 1500 GDSGISCSAEIGVGVTRASCCCSLGRAWGNPCEL--CPMANTTEYRTLCPGGEGF-QPNR 1556
Query: 1180 DLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPA 1239
+ D+DECQ +C+ G CVNT + C C GY+ C D DEC+
Sbjct: 1557 ITVILEDIDECQELPG-LCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSGI 1615
Query: 1240 CEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRL 1299
C G C NT+G+Y C C + C +D VC++ C + L
Sbjct: 1616 CGPGTCYNTLGNYTCVCPAEYLQVNGGNNC-------MDMRKSVCFRHYNG--TCQN-EL 1665
Query: 1300 DRQATYTECCCLY--GEAWGMDCALCPAQDSDDFEALCNVLRPPAYSPPRPGGFGLPYEY 1357
T CCC Y G+AW C CP S D++ LC P GF
Sbjct: 1666 AFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDYQILCGNQAP---------GFLTDIHT 1716
Query: 1358 GPDLGPPYQGLPYGPELYPPPALPYDPYPPPPGPFARREAPYGAPRFDMPDFEDDGGPYG 1417
G L E PA+ + R E P G + +D G
Sbjct: 1717 GKPLDI--------DECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECG 1768
Query: 1418 ESEAPAPPG------PGTRWPYRSRDTRRSFPEPEEPPEGGSYAGSLAEPYEELEAEEC- 1470
E+P PG+ YR + TR P GG+ G EC
Sbjct: 1769 SRESPCQQNADCINIPGS---YRCKCTRGYKLSP-----GGACVG----------RNECR 1810
Query: 1471 GILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTD 1530
I + C++G C+ + C C G++ + C+DI+ECD C N C N
Sbjct: 1811 EIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQP-----CGNGTCKNII 1865
Query: 1531 GSFRCICRPGFAPTH 1545
GS+ C+C PGF TH
Sbjct: 1866 GSYNCLCFPGFVVTH 1880
Score = 479 bits (1233), Expect = e-135
Identities = 362/1141 (31%), Positives = 475/1141 (41%), Gaps = 230/1141 (20%)
Query: 277 CPTGFE--RVNGSCEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHV 334
C G+E R G+C D++ECA C +G C NT G Y C CP F L+ S C+
Sbjct: 1430 CNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQDFELNPSGVGCVDTRA 1489
Query: 335 ISEAKGPCFRVLRDGG-----CSLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFR 389
G CF D G CS I +T+ CCCS +G+AWG C
Sbjct: 1490 -----GNCFLETHDRGDSGISCSAEIGVGVTRASCCCS-LGRAWGNPC------------ 1531
Query: 390 EICPAGPGYHYSASDLRYNTRPLGQE---PPRVS-----LSQPRTLPATSRPSAGFLPTH 441
E+CP A+ Y T G E P R++ + + + LP +
Sbjct: 1532 ELCPM-------ANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFG 1584
Query: 442 RLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGY 501
+ E P P + E C + +CGPG C + Y
Sbjct: 1585 SFQC------------ECP----PGYHLSEHTRICEDIDECSTHSGICGPGTCYNTLGNY 1628
Query: 502 TCACDSGFRLSPQGTRCIDVDE-------------------------------------C 524
TC C + + G C+D+ + C
Sbjct: 1629 TCVCPAEYLQVNGGNNCMDMRKSVCFRHYNGTCQNELAFNVTRKMCCCSYNIGQAWNRPC 1688
Query: 525 RRVPPPCAPGRCENSPGSFRCVCG---PGFRAGPRAAECLDVDECHRVPPPCDLGRCENT 581
P P +P ++ +CG PGF + LD+DEC +P C G C N
Sbjct: 1689 EACPTPISP--------DYQILCGNQAPGFLTDIHTGKPLDIDECGEIPAICANGICINQ 1740
Query: 582 PGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGA-CKNLPGSFRCVCPAGFR---G 637
GSF C CPAG+ +C+DVDEC C + A C N+PGS+RC C G++ G
Sbjct: 1741 IGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSPG 1800
Query: 638 SACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCT 697
AC +EC + P C G C +T GS+ C C GF++ C D+DEC R PC
Sbjct: 1801 GAC-VGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQ--PCG 1857
Query: 698 YGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHL--ACPGQECVNSPGSFQCRTCP 755
G C+N GS+ C+C GF T +C D DEC + C C+N+ GSF C C
Sbjct: 1858 NGTCKNIIGSYNCLCFPGFVV-THNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHC-LCQ 1915
Query: 756 SGHHLHRG--RCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVN 813
G L C D +EC S A C P G C N EGSFRC C PG++ S C D++
Sbjct: 1916 DGFELTADGKNCVDTNECLSLAGTCLP-GTCQNLEGSFRCICPPGFQVQSDH---CIDID 1971
Query: 814 ECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICT---- 869
EC E G C N+ GSF C C PG+ G C D + ++G C+
Sbjct: 1972 ECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKA 2031
Query: 870 -NT--------------------------DGSFECICPPGHRA--GPDLASCLDVDECRE 900
NT +F+ +CP GH A GPD S DV+EC E
Sbjct: 2032 FNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPD-DSREDVNECAE 2090
Query: 901 RGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEG-TCDDVDECQEYGPEICGAQRCENTP 959
P +C + C N+ GS+RC +C GY G C D DEC P CG C N
Sbjct: 2091 -NPGVCTNGVCVNTDGSFRC--ECPFGYSLDFTGINCVDTDECSVGHP--CGQGTCTNVI 2145
Query: 960 GSYRCTPACDPGYQPTPGGGCQDVDECR-NRSFCGAHAVCQNLPGSFQCLCDQGYEGARD 1018
G + C AC G++P C+D+DEC N C C N GS+ C C GY D
Sbjct: 2146 GGFEC--ACADGFEPGLMMTCEDIDECSLNPLLCAFR--CHNTEGSYLCTCPAGYTLRED 2201
Query: 1019 GRHCVDVNECETLQGVCGA--ALCENVEGSFLCVCPNSPEEFDP---------------- 1060
G C DV+EC Q C A C+N+ G+F CVCP
Sbjct: 2202 GAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPD 2261
Query: 1061 --MTGRCVPPRTSAGTF-----PGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGR 1113
+ GRCV +AG+F G QP SP L RQGP
Sbjct: 2262 LCVNGRCV---NTAGSFRCDCDEGFQP----SPTL----------TECHDIRQGPC---- 2300
Query: 1114 RECYFDTAAPDACDNILARN--VTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHG 1171
F C ++ + + VT ECCC G GWG C + CP T+ Y+ LCPHG
Sbjct: 2301 ----FAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCEL--CPLPGTSAYRKLCPHG 2354
Query: 1172 RGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDND 1231
GY A RDVDEC++ +C G C+N+ + C+C GY C+D D
Sbjct: 2355 SGYTAEG------RDVDECRMLA-HLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMD 2407
Query: 1232 ECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVS-NESQSLDDNLG-VCWQEVG 1289
EC+ C C NT GS+ C+C +L+ R C +E S N +C VG
Sbjct: 2408 ECSQVPKPCT-FLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVG 2466
Query: 1290 A 1290
A
Sbjct: 2467 A 2467
Score = 471 bits (1213), Expect = e-132
Identities = 382/1218 (31%), Positives = 508/1218 (41%), Gaps = 223/1218 (18%)
Query: 220 GYCFRELR-----GGECASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPD 274
G CF E G C++ + T+ CC G AWG + C+LC R P
Sbjct: 1490 GNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWG-NPCELCPMANTTEYRTLCPG 1548
Query: 275 GPCPTGFE--RVNGSCEDVDECAT-GGRCQHGECANTRGGYTCVCPDGFLLDSSRSSC-- 329
G GF+ R+ ED+DEC G CQ G+C NT G + C CP G+ L C
Sbjct: 1549 GE---GFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICED 1605
Query: 330 ---ISQHVISEAKGPCFRVL-------------------------------RDGGCSLPI 355
S H G C+ L +G C +
Sbjct: 1606 IDECSTHSGICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHYNGTCQNEL 1665
Query: 356 LRNITKQICCCS-RVGKAWGRGCQLCPPFGSEGFREIC-PAGPGYHYSASDLRYNTRPL- 412
N+T+++CCCS +G+AW R C+ CP S ++ +C PG+ +D+ + +PL
Sbjct: 1666 AFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDYQILCGNQAPGF---LTDI-HTGKPLD 1721
Query: 413 ----GQEPP----RVSLSQPRTL----PATSRPSAGFLPTHRL-EPRPEPRPDPRPGPEL 459
G+ P + ++Q + PA ++ L + E P + +
Sbjct: 1722 IDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCI 1781
Query: 460 PLPS---IPAWTGPEIPESGPSSGM--CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQ 514
+P G ++ G G C+ P VC G C+ Y C C GF+ S
Sbjct: 1782 NIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASAD 1841
Query: 515 GTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHR-VPPPC 573
T C+D+DEC R PC G C+N GS+ C+C PGF +C+D DEC V C
Sbjct: 1842 QTLCMDIDECDR--QPCGNGTCKNIIGSYNCLCFPGF-VVTHNGDCVDFDECTTLVGQVC 1898
Query: 574 DLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPA 633
G C NT GSF C+C G++ G +C D +EC G C G C+NL GSFRC+CP
Sbjct: 1899 RFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCICPP 1958
Query: 634 GFRGSACE-EDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDE---- 688
GF+ + D+DEC++EP C G C N+ GSF C CP GF G C D +
Sbjct: 1959 GFQVQSDHCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCF 2018
Query: 689 ----------------------CARSPPPCTYGRCE--NTEGS--FQCVCPMGF--QPNT 720
C++ P CE EGS FQ +CP G P
Sbjct: 2019 TRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGP 2078
Query: 721 AGSECEDVDEC-ENHLACPGQECVNSPGSFQCRTCPSGHHLHRG--RCTDVDECSSGAPP 777
S EDV+EC EN C CVN+ GSF+C CP G+ L C D DECS G P
Sbjct: 2079 DDSR-EDVNECAENPGVCTNGVCVNTDGSFRCE-CPFGYSLDFTGINCVDTDECSVG-HP 2135
Query: 778 CGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNEC-LEGDFCFPHGECLNTDGSFAC 836
CG G CTN G F C+CA G+ G C D++EC L C C NT+GS+ C
Sbjct: 2136 CG-QGTCTNVIGGFECACADGFE--PGLMMTCEDIDECSLNPLLC--AFRCHNTEGSYLC 2190
Query: 837 TCAPGYRPGPRGASCLDVDECS--EEDLCQSGI-CTNTDGSFECICPPGHRAGPDLA-SC 892
TC GY GA C DVDEC+ ++D G+ C N G+F C+CPPG R P C
Sbjct: 2191 TCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGC 2250
Query: 893 LDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGT-CDDVDE---------- 941
D +EC + P LC + RC N+ GS+RC DCD G+ P T C D+ +
Sbjct: 2251 TDDNECHAQ-PDLCVNGRCVNTAGSFRC--DCDEGFQPSPTLTECHDIRQGPCFAEVLQT 2307
Query: 942 -CQEYGPE---------ICG-----AQRCE--NTPGSYRCTPACDPGYQPTPGGGCQDVD 984
C+ CG RCE PG+ C G T G +DVD
Sbjct: 2308 MCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEG--RDVD 2365
Query: 985 ECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVE 1044
ECR + AH C N GSF+C C GY C+D++EC + C LC+N +
Sbjct: 2366 ECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPC-TFLCKNTK 2424
Query: 1045 GSFLCVCP---------NSPEEFDPMTGR-------CVPPRTSAGTFPGSQPQAPASPVL 1088
GSFLC CP + ++ D T R CV + G F P
Sbjct: 2425 GSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCV---NTVGAFTCRCP-------- 2473
Query: 1089 PARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGW- 1147
P + EC +A P C + T C +G+
Sbjct: 2474 ------------PGFTQHHQACFDNDEC---SAQPGPCGAHGHCHNTPGSFRCECHQGFT 2518
Query: 1148 ----GSGCR-IQQCPGTETAE---------YQSLCPHGRGYLAPSGDLSLRRDVDECQLF 1193
G GC + +C G + Y+ CP G + D +EC L
Sbjct: 2519 LVSSGHGCEDVNECDGPHRCQHGCQNQLGGYRCSCPQG---FTQHSQWAQCVDENECAL- 2574
Query: 1194 RDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYH 1253
C S C NT G+ C C +G+ + C + DECA C C NT G +
Sbjct: 2575 SPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQEVDECAGRRGPCSYS-CANTPGGFL 2633
Query: 1254 CTCEPPLVLDGSQRRCVS 1271
C C P Q CVS
Sbjct: 2634 CGC-PQGYFRAGQGHCVS 2650
Score = 469 bits (1208), Expect = e-132
Identities = 396/1228 (32%), Positives = 494/1228 (40%), Gaps = 257/1228 (20%)
Query: 220 GYCFRELRGGECASPLPGLR-TQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCP 278
G CF ++ C L GL T+ +CC G AWG+ C+LC A PC
Sbjct: 185 GPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGL-PCELCP----------AQPHPCR 233
Query: 279 TGF--ERVNGSCEDVDEC-ATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVI 335
GF G+C+DVDEC A G CQ G C N G + C CP G L S ++C
Sbjct: 234 RGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRA- 292
Query: 336 SEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGC--QLCPPFGSEGFREIC- 392
G CF VL G C+ + + T++ CCC R G+ W G +LCPP GS F+++C
Sbjct: 293 ----GACFSVLFGGRCAGDLAGHYTRRQCCCDR-GRCWAAGPVPELCPPRGSNEFQQLCA 347
Query: 393 ---PAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEP 449
P PG+ P P GF P
Sbjct: 348 QRLPLLPGH-------------------------PGLFPGL----LGFGSNGMGPPLGPA 378
Query: 450 RPDPRPGPELPLPSIPAWTGPEIPESGPSS-----GMCQRNPQVCGPGRCISRPSGYTCA 504
R +P +PS+ GP G ++ +C+ +C GRC+ PS Y C
Sbjct: 379 RLNPHGSDARGIPSL----GPGNSNIGTATLNQTIDICRHFTNLCLNGRCLPTPSSYRCE 434
Query: 505 CDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVD 564
C+ G+ +G CIDVDEC PC G C N PG++ C C PGF+A P C+DVD
Sbjct: 435 CNVGYTQDVRG-ECIDVDEC--TSSPCHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVD 491
Query: 565 ECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLP 624
EC C LGRC NT GSF CVC AG++ +P G +C D +EC S +C G C N
Sbjct: 492 ECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATST-MCVNGVCLNED 550
Query: 625 GSFRCVCPAGF----RGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPG 680
GSF C+C GF G C D+DEC Q P C G C NT GSF C C G G
Sbjct: 551 GSFSCLCKPGFLLAPGGHYC-MDIDEC-QTPGICVNGHCTNTEGSFRCQCLGGLAVGTDG 608
Query: 681 APCQDV------------DECARSPP-------------------PC------------- 696
C D CAR P PC
Sbjct: 609 RVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKDSAEFQA 668
Query: 697 ---------TYGR-----------CEN-----TEGSFQCVCPMGFQPNTAGSECEDVDEC 731
T GR C N GS++CVC +G++ +G +C DVDEC
Sbjct: 669 LCSSGLGITTDGRDINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDEC 728
Query: 732 E-NHLACPGQECVNSPGSFQCRTCPSGHHLHRGR--CTDVDECSSGAPPCGPHGHCTNTE 788
N L C C NSPGS+ C +CP G H + C DVDEC S PC G C N
Sbjct: 729 ALNSLLCDNGWCQNSPGSYSC-SCPPGFHFWQDTEICKDVDECLSS--PC-VSGVCRNLA 784
Query: 789 GSFRCSCAPGYRA-PSG------RPGPC--------ADVNECLEGDFCFPHGECLNTDGS 833
GS+ C C PG R PSG G C +VN L+G EC T G+
Sbjct: 785 GSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVN--LQG--ASLRSECCATLGA 840
Query: 834 ----------FACTCAPGYRPGPRGASCLDVDEC-SEEDLCQSGICTNTDGSFECICPPG 882
CA G+ G +C DV+EC S +C +G C NT GSF C CP G
Sbjct: 841 AWGSPCERCEIDPACARGF-ARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEG 899
Query: 883 HRAGPDLASCLDV-----------DECRERGPALCGSQR---------------CE--NS 914
C+DV DEC G L G R CE
Sbjct: 900 LMLDASGRLCVDVRLEPCFLRWDEDEC---GVTLPGKYRMDVCCCSIGAVWGVECEACPD 956
Query: 915 PGSYRCVRDCDPGYHAGPEGTCD------DVDECQEYGPEICGAQRCENTPGSYRCTPAC 968
P S C G DV+EC+ + P +C C NT GS+ C AC
Sbjct: 957 PESLEFASLCPRGLGFASRDFLSGRPFYKDVNECKVF-PGLCTHGTCRNTVGSFHC--AC 1013
Query: 969 DPGYQ-PTPGGGCQDVDECR-NRSFCGAHAVCQNLPGSFQCLCDQGYE-GARDGRHCVDV 1025
G+ C D+DECR + CG C N PGSF+C C GYE G ++C+DV
Sbjct: 1014 AGGFALDAQERNCTDIDECRISPDLCG-QGTCVNTPGSFECECFPGYESGFMLMKNCMDV 1072
Query: 1026 NECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPAS 1085
+EC +C C N +GS+ C CP P G G P
Sbjct: 1073 DECARDPLLCRGGTCTNTDGSYKCQCP--PGHELTAKGTACEDIDECSLSDGLCPHGQCV 1130
Query: 1086 PVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDA-CDNILARNVTWQECCCTVG 1144
V+ A + + RQG V EC D C N T C+ G
Sbjct: 1131 NVIGAFQCSCHAGFQSTPDRQGCVDI--NECRVQNGGCDVHCIN------TEGSYRCSCG 1182
Query: 1145 EGW-----GSGCR-IQQCPGTETAEYQSLC---PHGRGYLAPSG-----DLSLRRDVDEC 1190
+G+ G C + +C Q C P G L G D+ DVDEC
Sbjct: 1183 QGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDEC 1242
Query: 1191 QLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEG-GRCVNTV 1249
L +C G C NT + C+C GY C D DEC C+ C+N
Sbjct: 1243 DL-NPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIP 1301
Query: 1250 GSYHCTCEPPLVLDGSQ----RRCVSNE 1273
GS+ C C P V DG + CVS E
Sbjct: 1302 GSFSCRCLPGWVGDGFECHDLDECVSQE 1329
Score = 468 bits (1205), Expect = e-131
Identities = 419/1519 (27%), Positives = 556/1519 (36%), Gaps = 325/1519 (21%)
Query: 222 CFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQ------------LCSERLGNSER 269
CF EC LPG +VCC G WGV +C+ LC LG + R
Sbjct: 917 CFLRWDEDECGVTLPGKYRMDVCCCSIGAVWGV-ECEACPDPESLEFASLCPRGLGFASR 975
Query: 270 VSAPDGP------------------------------CPTGF--ERVNGSCEDVDECATG 297
P C GF + +C D+DEC
Sbjct: 976 DFLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRIS 1035
Query: 298 -GRCQHGECANTRGGYTCVC----PDGFLLDSSR---SSCISQHVISEAKGPCFRVLRDG 349
C G C NT G + C C GF+L + C ++ G C
Sbjct: 1036 PDLCGQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRG-GTCTNTDGSY 1094
Query: 350 GCSLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREICPAGP-----GYHYSASD 404
C P +T + C + + C L S+G +CP G G +
Sbjct: 1095 KCQCPPGHELTAKGTACEDIDE-----CSL-----SDG---LCPHGQCVNVIGAFQCSCH 1141
Query: 405 LRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSI 464
+ + P Q ++ R G H + R G L
Sbjct: 1142 AGFQSTPDRQGCVDIN---------ECRVQNGGCDVHCINTEGSYRCSCGQGYSL----- 1187
Query: 465 PAWTGPEIPESGPSSGM--CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVD 522
+P+ + + C+ NP+VC G C + P G+ C C GF +P C+DVD
Sbjct: 1188 -------MPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVD 1240
Query: 523 ECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDL-GRCENT 581
EC P C G CEN+ GSF C C G+ A C DVDEC CD C N
Sbjct: 1241 ECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNI 1300
Query: 582 PGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCG-RGACKNLPGSFRCVCPAGFRGSA- 639
PGSF C C G+ G C D+DEC C RG C N+PGS+RC C GF G
Sbjct: 1301 PGSFSCRCLPGWVG--DGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGF 1358
Query: 640 -CEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTY 698
CE D DECA+ C G+C N G + C C GF CQDVDECA+ C +
Sbjct: 1359 FCE-DRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNL-CAF 1416
Query: 699 GRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGH 758
G CEN G F+C+C G++ + G C D++EC + + C C+N+PGS+ C +CP
Sbjct: 1417 GSCENLPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLC-SCPQDF 1475
Query: 759 HLHRGRCTDVDE---------------------------------CSSGAP---PCGPHG 782
L+ VD CS G PC
Sbjct: 1476 ELNPSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWGNPCELCP 1535
Query: 783 HCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGY 842
TE C G++ P+ D++EC E G+C+NT GSF C C PGY
Sbjct: 1536 MANTTEYRTLCPGGEGFQ-PNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGY 1594
Query: 843 RPGPRGASCLDVDECSEED-LCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDE--CR 899
C D+DECS +C G C NT G++ C+CP + +C+D+ + C
Sbjct: 1595 HLSEHTRICEDIDECSTHSGICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCF 1654
Query: 900 ERGPALCGSQRCENSPGSYRCV---------RDCD-------PGY-----HAGPEGTCD- 937
C ++ N C R C+ P Y + P D
Sbjct: 1655 RHYNGTCQNELAFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDYQILCGNQAPGFLTDI 1714
Query: 938 ------DVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGG-GCQDVDECRNR- 989
D+DEC E P IC C N GS+RC C G+ C+DVDEC +R
Sbjct: 1715 HTGKPLDIDECGEI-PAICANGICINQIGSFRCE--CPAGFNYNSILLACEDVDECGSRE 1771
Query: 990 SFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLC 1049
S C +A C N+PGS++C C +GY+ + G CV NEC + VC C + EGS++C
Sbjct: 1772 SPCQQNADCINIPGSYRCKCTRGYKLSPGGA-CVGRNECREIPNVCSHGDCMDTEGSYMC 1830
Query: 1050 VCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRP--STPRQG 1107
+C F S Q + R+P + +
Sbjct: 1831 LCHRG--------------------FQASADQTLCMDI-------DECDRQPCGNGTCKN 1863
Query: 1108 PVGSGRRECY--FDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQ 1165
+GS C+ F C V + EC VG+ CR C T +
Sbjct: 1864 IIGSYNCLCFPGFVVTHNGDC-------VDFDECTTLVGQV----CRFGHCLNT-AGSFH 1911
Query: 1166 SLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRL 1225
LC G A + D +EC L C G C N + C C G+ Q
Sbjct: 1912 CLCQDGFELTADGKNCV---DTNEC-LSLAGTCLPGTCQNLEGSFRCICPPGF--QVQSD 1965
Query: 1226 ECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCW 1285
CID DEC++E C G C N+ GS+ C C P VL + RC D C+
Sbjct: 1966 HCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRC-------FDTRQSFCF 2018
Query: 1286 QEVGADLVCSHPRLDRQATYTECCCLY--GEAWGMDCALCPAQDSDDFEALCNVLRPPAY 1343
A CS P+ T T CCC GE WG C LCP + S F+ LC
Sbjct: 2019 TRFEAG-KCSVPKA-FNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELC-------- 2068
Query: 1344 SPPRPGGFGLPYEYGPDLGPPYQGLPYGPELYPPPALPYDPYPPPPGPFARREAPYGAPR 1403
P+ +G GP P G F R E P+G
Sbjct: 2069 ----------PFGHGAVPGPDDSREDVNECAENPGVCTNGVCVNTDGSF-RCECPFG--- 2114
Query: 1404 FDMPDFEDDGGPYGESEAPAPPGPGTRWPYRSRDTRRSFPEPEEPPEGGSYAGSLAEPYE 1463
+ + + E P G GT G + + A+ +E
Sbjct: 2115 YSLDFTGINCVDTDECSVGHPCGQGTCTNVI-----------------GGFECACADGFE 2157
Query: 1464 ELEAEECGILDGCTNG------RCVRVPEGFTCRCFDGYRLDMTRMACVDINEC------ 1511
C +D C+ RC + C C GY L C D++EC
Sbjct: 2158 PGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQD 2217
Query: 1512 ------------------------------------DEAEAASPLCVNARCLNTDGSFRC 1535
+E A LCVN RC+NT GSFRC
Sbjct: 2218 CHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRC 2277
Query: 1536 ICRPGFAPTHQPHHCAPAR 1554
C GF P+ C R
Sbjct: 2278 DCDEGFQPSPTLTECHDIR 2296
Score = 424 bits (1091), Expect = e-118
Identities = 313/903 (34%), Positives = 397/903 (43%), Gaps = 111/903 (12%)
Query: 482 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGR-CENSP 540
C P +C G CI++ + C C +GF + C DVDEC PC C N P
Sbjct: 1725 CGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIP 1784
Query: 541 GSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGA 600
GS+RC C G++ P A C+ +EC +P C G C +T GS++C+C G+QA+
Sbjct: 1785 GSYRCKCTRGYKLSPGGA-CVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQT 1843
Query: 601 SCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGF---RGSACEEDVDECAQ-EPPPCGP 656
C D+DEC + P CG G CKN+ GS+ C+C GF C D DEC C
Sbjct: 1844 LCMDIDECDRQP--CGNGTCKNIIGSYNCLCFPGFVVTHNGDC-VDFDECTTLVGQVCRF 1900
Query: 657 GRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGF 716
G C NTAGSFHC C GF G C D +EC C G C+N EGSF+C+CP GF
Sbjct: 1901 GHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCICPPGF 1960
Query: 717 QPNTAGSECEDVDEC-ENHLACPGQECVNSPGSFQCRTCPSGHHL----HR--------- 762
Q C D+DEC E C C NSPGSFQC CP G L HR
Sbjct: 1961 Q--VQSDHCIDIDECSEEPNLCLFGTCTNSPGSFQC-LCPPGFVLSDNGHRCFDTRQSFC 2017
Query: 763 ------GRC--------TDVDECSSGAPPCGPHGHC--TNTEGS--FRCSCAPGYRAPSG 804
G+C T C S P G C EGS F+ C G+ A G
Sbjct: 2018 FTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPG 2077
Query: 805 RPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQ 864
DVNEC E +G C+NTDGSF C C GY G +C+D DECS C
Sbjct: 2078 PDDSREDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCG 2137
Query: 865 SGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDC 924
G CTN G FEC C G G + +C D+DEC P LC + RC N+ GSY C C
Sbjct: 2138 QGTCTNVIGGFECACADGFEPGL-MMTCEDIDEC-SLNPLLC-AFRCHNTEGSYLCT--C 2192
Query: 925 DPGYHAGPEGT-CDDVDECQEYGPEICGAQ--RCENTPGSYRCTPACDPGYQPTPGG--G 979
GY +G C DVDEC + G + C A+ C+N G++ C C PG +P PG G
Sbjct: 2193 PAGYTLREDGAMCRDVDECAD-GQQDCHARGMECKNLIGTFAC--VCPPGMRPLPGSGEG 2249
Query: 980 CQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAAL 1039
C D +EC + + C N GSF+C CD+G++ + C D+ QG C A +
Sbjct: 2250 CTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIR-----QGPCFAEV 2304
Query: 1040 CENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPR 1099
+ +C +S E C G G P+ P+ P R
Sbjct: 2305 LQT-----MCRSLSSSSEAVTRAECC------CGGGRGWGPRCELCPL-----PGTSAYR 2348
Query: 1100 RPSTPRQGPVGSGR--RECYF--DTAAPDACDNILARNVTWQECCCTVG---EGWGSGC- 1151
+ G GR EC A C N L C C G + + C
Sbjct: 2349 KLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGS----FRCHCQAGYTPDATATTCL 2404
Query: 1152 RIQQC-----PGT---ETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVC 1203
+ +C P T + + LC RGYL D +D+DEC R C+ +C
Sbjct: 2405 DMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEE-DGRTCKDLDEC-TSRQHNCQF-LC 2461
Query: 1204 VNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEG-GRCVNTVGSYHCTCEPPLVL 1262
VNT ++C C G+ H Q C DNDEC+ + C G C NT GS+ C C L
Sbjct: 2462 VNTVGAFTCRCPPGFTQHHQ--ACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTL 2519
Query: 1263 DGSQRRCVS-NESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLYGEAWGMDCA 1321
S C NE C ++G CS P+ Q + C E CA
Sbjct: 2520 VSSGHGCEDVNECDGPHRCQHGCQNQLGG-YRCSCPQGFTQHSQWAQCVDENE-----CA 2573
Query: 1322 LCP 1324
L P
Sbjct: 2574 LSP 2576
Score = 386 bits (991), Expect = e-106
Identities = 290/964 (30%), Positives = 387/964 (40%), Gaps = 141/964 (14%)
Query: 488 VCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVC 547
+C G C + P + C C+ G+ L G C D++EC P C G C N+PGS+ C C
Sbjct: 1413 LCAFGSCENLPGMFRCICNGGYELDRGGGNCTDINECAD-PVNCINGVCINTPGSYLCSC 1471
Query: 548 GPGFRAGPRAAECLDVD------ECH------------------RVPPPCDLGR-----C 578
F P C+D E H R C LGR C
Sbjct: 1472 PQDFELNPSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWGNPC 1531
Query: 579 ENTPGS----FLCVCPAGYQAAPHGASC--QDVDECTQSPGLCGRGACKNLPGSFRCVCP 632
E P + + +CP G P+ + +D+DEC + PGLC G C N GSF+C CP
Sbjct: 1532 ELCPMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECP 1591
Query: 633 AGFRGSACE---EDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDEC 689
G+ S ED+DEC+ CGPG C NT G++ C CPA + G C D+ +
Sbjct: 1592 PGYHLSEHTRICEDIDECSTHSGICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKS 1651
Query: 690 A------------------RSPPPCTYG-------RCENT----EGSFQCVC---PMGFQ 717
R C+Y CE +Q +C GF
Sbjct: 1652 VCFRHYNGTCQNELAFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDYQILCGNQAPGFL 1711
Query: 718 PNTAGSECEDVDEC-ENHLACPGQECVNSPGSFQCRTCPSGHHLHRG--RCTDVDECSSG 774
+ + D+DEC E C C+N GSF+C CP+G + + C DVDEC S
Sbjct: 1712 TDIHTGKPLDIDECGEIPAICANGICINQIGSFRCE-CPAGFNYNSILLACEDVDECGSR 1770
Query: 775 APPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSF 834
PC + C N GS+RC C GY+ G G C NEC E HG+C++T+GS+
Sbjct: 1771 ESPCQQNADCINIPGSYRCKCTRGYKLSPG--GACVGRNECREIPNVCSHGDCMDTEGSY 1828
Query: 835 ACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLD 894
C C G++ C+D+DEC + C +G C N GS+ C+C PG + C+D
Sbjct: 1829 MCLCHRGFQASADQTLCMDIDECDRQP-CGNGTCKNIIGSYNCLCFPGFVVTHN-GDCVD 1886
Query: 895 VDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEG-TCDDVDECQEYGPEICGAQ 953
DEC +C C N+ GS+ C+ C G+ +G C D +EC C
Sbjct: 1887 FDECTTLVGQVCRFGHCLNTAGSFHCL--CQDGFELTADGKNCVDTNECLSLAGT-CLPG 1943
Query: 954 RCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGY 1013
C+N GS+RC C PG+Q C D+DEC C N PGSFQCLC G+
Sbjct: 1944 TCQNLEGSFRCI--CPPGFQ-VQSDHCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGF 2000
Query: 1014 EGARDGRHCVDVNE--CETL--QGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPR 1069
+ +G C D + C T G C N + C E + C P+
Sbjct: 2001 VLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELC--PQ 2058
Query: 1070 TSAGTFPGSQPQAPASPVLP--ARPPPPPLPRRPSTPRQGPV----GSGRRECYF----- 1118
+ F P + P +R P G GS R EC F
Sbjct: 2059 EGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLD 2118
Query: 1119 ----------DTAAPDACDNILARNVTWQ-ECCCTVGEGWG--------SGCRIQ----- 1154
+ + C NV EC C G G C +
Sbjct: 2119 FTGINCVDTDECSVGHPCGQGTCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCA 2178
Query: 1155 -QCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGV-CVNTAPGYSC 1212
+C TE Y CP G D ++ RDVDEC + G+ C N ++C
Sbjct: 2179 FRCHNTE-GSYLCTCPAG---YTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFAC 2234
Query: 1213 YCSNGYYYHTQRLE-CIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVS 1271
C G E C D++EC + C GRCVNT GS+ C C+ +G Q
Sbjct: 2235 VCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCD-----EGFQPSPTL 2289
Query: 1272 NESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLYGEAWGMDCALCPAQDSDDF 1331
E D G C+ EV + S T ECCC G WG C LCP + +
Sbjct: 2290 TECH--DIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAY 2347
Query: 1332 EALC 1335
LC
Sbjct: 2348 RKLC 2351
Score = 367 bits (943), Expect = e-101
Identities = 300/982 (30%), Positives = 400/982 (40%), Gaps = 182/982 (18%)
Query: 198 APYTVLAQSAPREDGYSDAS----GFGYCFRELRGG--------ECASPLPGLRTQEVC- 244
A + V ++ P + AS G G+ R+ G EC PGL T C
Sbjct: 945 AVWGVECEACPDPESLEFASLCPRGLGFASRDFLSGRPFYKDVNEC-KVFPGLCTHGTCR 1003
Query: 245 -------CRGAG---------LAWGVHDCQLCSERLGNSERVSAPDG---PCPTGFER-- 283
C AG + +C++ + G V+ P C G+E
Sbjct: 1004 NTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGF 1063
Query: 284 -VNGSCEDVDECATGGR-CQHGECANTRGGYTCVCPDGFLLDSSRSSC--ISQHVISEA- 338
+ +C DVDECA C+ G C NT G Y C CP G L + ++C I + +S+
Sbjct: 1064 MLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSDGL 1123
Query: 339 --KGPCFRVLRDGGCSLPILRNIT--KQICCCSRVGKAWGRGCQL-CPPFGSEGFREICP 393
G C V+ CS T +Q C + GC + C +EG C
Sbjct: 1124 CPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHC--INTEGSYR-CS 1180
Query: 394 AGPGYHYSASDLRYNTRPLGQEPPRV-SLSQPRTLPATSRPSA--GFLPTHRLEPRPEPR 450
G GY +E PRV +P R GF+ T
Sbjct: 1181 CGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMAT---------- 1230
Query: 451 PDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFR 510
PD R T ++ E C NP +C G C + + C C G+
Sbjct: 1231 PDMR-------------TCVDVDE-------CDLNPHICLHGDCENTKGSFVCHCQLGYM 1270
Query: 511 LSPQGTRCIDVDECRRVPPPC-APGRCENSPGSFRCVCGPGFRAGPRAAECLDVDEC--- 566
+ T C DVDEC C + C N PGSF C C PG+ EC D+DEC
Sbjct: 1271 VRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWVGD--GFECHDLDECVSQ 1328
Query: 567 -HRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLPG 625
HR P G C N PGS+ C C G+ A G C+D DEC ++ LC G C N PG
Sbjct: 1329 EHRCSP---RGDCLNVPGSYRCTCRQGF--AGDGFFCEDRDECAENVDLCDNGQCLNAPG 1383
Query: 626 SFRCVCPAGFRGS----ACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGA 681
+RC C GF + AC +DVDECAQ C G C+N G F C C G+ G
Sbjct: 1384 GYRCECEMGFDPTEDHRAC-QDVDECAQ-GNLCAFGSCENLPGMFRCICNGGYELDRGGG 1441
Query: 682 PCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDV----------DEC 731
C D++ECA P C G C NT GS+ C CP F+ N +G C D D
Sbjct: 1442 NCTDINECA-DPVNCINGVCINTPGSYLCSCPQDFELNPSGVGCVDTRAGNCFLETHDRG 1500
Query: 732 ENHLACP--------------------GQECVNSP--GSFQCRT-CPSGHHLHRGRCT-- 766
++ ++C G C P + + RT CP G R T
Sbjct: 1501 DSGISCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLCPGGEGFQPNRITVI 1560
Query: 767 --DVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNEC-LEGDFCFP 823
D+DEC P G C NT GSF+C C PGY S C D++EC C P
Sbjct: 1561 LEDIDECQE-LPGLCQGGDCVNTFGSFQCECPPGYHL-SEHTRICEDIDECSTHSGICGP 1618
Query: 824 HGECLNTDGSFACTCAPGYRPGPRGASCLDVDEC----SEEDLCQSGICTNTDGSFEC-- 877
G C NT G++ C C Y G +C+D+ + CQ+ + N C
Sbjct: 1619 -GTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHYNGTCQNELAFNVTRKMCCCS 1677
Query: 878 ------------ICP---------------PGHRAGPDLASCLDVDECRERGPALCGSQR 910
CP PG LD+DEC E PA+C +
Sbjct: 1678 YNIGQAWNRPCEACPTPISPDYQILCGNQAPGFLTDIHTGKPLDIDECGEI-PAICANGI 1736
Query: 911 CENSPGSYRCVRDCDPGYHAGP-EGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACD 969
C N GS+RC +C G++ C+DVDEC C N PGSYRC C
Sbjct: 1737 CINQIGSFRC--ECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRC--KCT 1792
Query: 970 PGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECE 1029
GY+ +PGG C +ECR +H C + GS+ CLC +G++ + D C+D++EC+
Sbjct: 1793 RGYKLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECD 1852
Query: 1030 TLQGVCGAALCENVEGSFLCVC 1051
+ CG C+N+ GS+ C+C
Sbjct: 1853 --RQPCGNGTCKNIIGSYNCLC 1872
Score = 353 bits (906), Expect = 7e-97
Identities = 283/866 (32%), Positives = 368/866 (42%), Gaps = 101/866 (11%)
Query: 277 CPTGFERVNGS--CEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSS------ 328
C GF+ C D+DEC C +G C N G Y C+C GF++ +
Sbjct: 1832 CHRGFQASADQTLCMDIDECDRQP-CGNGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDEC 1890
Query: 329 -------CISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCP 381
C H ++ A G + +DG +N C S G CQ
Sbjct: 1891 TTLVGQVCRFGHCLNTA-GSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQ--- 1946
Query: 382 PFGSEG-FREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPT 440
EG FR ICP PG+ SD + +EP P + + P
Sbjct: 1947 --NLEGSFRCICP--PGFQVQ-SDHCIDIDECSEEPNLCLFGTCTNSPGSFQCLCP--PG 1999
Query: 441 HRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSG 500
L D R + P+ + + C + P C P
Sbjct: 2000 FVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQE 2059
Query: 501 YT------CACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAG 554
+ C G P +R DV+EC P C G C N+ GSFRC C G+
Sbjct: 2060 GSAAFQELCPFGHGAVPGPDDSR-EDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLD 2118
Query: 555 PRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGL 614
C+D DEC V PC G C N G F C C G++ +C+D+DEC+ +P L
Sbjct: 2119 FTGINCVDTDECS-VGHPCGQGTCTNVIGGFECACADGFEPGLM-MTCEDIDECSLNPLL 2176
Query: 615 CGRGACKNLPGSFRCVCPAGFR----GSACEEDVDECAQEPPPCGPG--RCDNTAGSFHC 668
C C N GS+ C CPAG+ G+ C DVDECA C C N G+F C
Sbjct: 2177 CAF-RCHNTEGSYLCTCPAGYTLREDGAMCR-DVDECADGQQDCHARGMECKNLIGTFAC 2234
Query: 669 ACPAGFRSR-GPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECED 727
CP G R G G C D +EC P C GRC NT GSF+C C GFQP+ +EC D
Sbjct: 2235 VCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHD 2294
Query: 728 VDE---------------CENHLACPGQECVNSPGSF---QCRTCP-SGHHLHRGRCT-- 766
+ + + A EC G +C CP G +R C
Sbjct: 2295 IRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHG 2354
Query: 767 --------DVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEG 818
DVDEC A C HG C N+ GSFRC C GY P C D++EC +
Sbjct: 2355 SGYTAEGRDVDECRMLAHLCA-HGECINSLGSFRCHCQAGY-TPDATATTCLDMDECSQV 2412
Query: 819 DFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDEC-SEEDLCQSGICTNTDGSFEC 877
C NT GSF C+C GY G +C D+DEC S + CQ +C NT G+F C
Sbjct: 2413 PKPCTF-LCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQF-LCVNTVGAFTC 2470
Query: 878 ICPPGHRAGPDLASCLDVDECRERGPALCGSQ-RCENSPGSYRCVRDCDPGYHAGPEGT- 935
CPPG +C D DEC + P CG+ C N+PGS+RC +C G+ G
Sbjct: 2471 RCPPGFTQHHQ--ACFDNDECSAQ-PGPCGAHGHCHNTPGSFRC--ECHQGFTLVSSGHG 2525
Query: 936 CDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGY-QPTPGGGCQDVDECR-NRSFCG 993
C+DV+EC GP C C+N G YRC+ C G+ Q + C D +EC + CG
Sbjct: 2526 CEDVNECD--GPHRC-QHGCQNQLGGYRCS--CPQGFTQHSQWAQCVDENECALSPPTCG 2580
Query: 994 AHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPN 1053
+ A C+N G F+C+C G++ + C +V+EC +G C + C N G FLC CP
Sbjct: 2581 S-ASCRNTLGGFRCVCPSGFDFDQALGGCQEVDECAGRRGPCSYS-CANTPGGFLCGCPQ 2638
Query: 1054 SPEEFDPMTGRCVPPRTSAGTFPGSQ 1079
F G CV + G PG Q
Sbjct: 2639 G--YFRAGQGHCV---SGLGFSPGPQ 2659
Score = 346 bits (888), Expect = 9e-95
Identities = 339/1149 (29%), Positives = 438/1149 (38%), Gaps = 190/1149 (16%)
Query: 51 GSRCTPTCAP----RNATSVDSGAPGGAAPGGPGFRAFLCPLICHNGGVCVKPDRCLCPP 106
GS C+ +C R A+ + G G P +C CHNGG C+ P+RC C
Sbjct: 117 GSGCSVSCMNGGTCRGASCLCQKGYTGTVCGQP-----ICDRGCHNGGRCIGPNRCACVY 171
Query: 107 DFAGKFCQLH-----SSGARPPAPAVPGLTRSVYTMPLANHR-DDEHGVASMVSVHVEHP 160
F G C+ G P LT V T L G+ + HP
Sbjct: 172 GFMGPQCERDYRTGPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQPHP 231
Query: 161 QEASVV--VH-----QVERVSGPWEEADAEAVARAEAAARAEAAAPYTVLAQSAPREDGY 213
+ +H V+ + + + + SA ED
Sbjct: 232 CRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYR 291
Query: 214 SDASGFGYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDC-------------QLC 260
+ A CF L GG CA L G T+ CC G W QLC
Sbjct: 292 AGA-----CFSVLFGGRCAGDLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLC 346
Query: 261 SERLG---------------NSERVSAPDGPC---PTGFERVN-----------GSC--- 288
++RL S + P GP P G + G+
Sbjct: 347 AQRLPLLPGHPGLFPGLLGFGSNGMGPPLGPARLNPHGSDARGIPSLGPGNSNIGTATLN 406
Query: 289 EDVDECA-TGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEA---KGPCFR 344
+ +D C C +G C T Y C C G+ D R CI + + G C
Sbjct: 407 QTIDICRHFTNLCLNGRCLPTPSSYRCECNVGYTQD-VRGECIDVDECTSSPCHHGDCVN 465
Query: 345 VLRDGGCSL--PILRNITKQICCCSRVGKAWGRGCQLCPPFGSEG-FREICPAG----PG 397
+ C T+Q C G C L +EG F+ +C AG P
Sbjct: 466 IPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPD 525
Query: 398 YHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGP 457
T + V L++ + +P GFL L P D
Sbjct: 526 GKNCVDHNECATSTMCVN--GVCLNEDGSFSCLCKP--GFL----LAPGGHYCMDI---D 574
Query: 458 ELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGR-CISRPSGYTC-------ACDSGF 509
E P I G G C V GR C+ TC +C F
Sbjct: 575 ECQTPGI-CVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPF 633
Query: 510 RLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRV 569
+ + C + PC ++S F+ +C G + D++EC
Sbjct: 634 PGTVTKSECCCANPDHGFGEPCQLCPAKDS-AEFQALCSSGLGI---TTDGRDINECALD 689
Query: 570 PPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRC 629
P C G CEN GS+ CVC GY+A G C DVDEC + LC G C+N PGS+ C
Sbjct: 690 PEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSC 749
Query: 630 VCPAGF---RGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDV 686
CP GF + + +DVDEC PC G C N AGS+ C C G R G C D
Sbjct: 750 SCPPGFHFWQDTEICKDVDECLSS--PCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDS 807
Query: 687 ------------------------DECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAG 722
EC + CE E C GF T G
Sbjct: 808 TKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGSPCERCE--IDPACARGFARMT-G 864
Query: 723 SECEDVDECENHL-ACPGQECVNSPGSFQCRTCPSGHHLH-RGR-CTDV----------- 768
C+DV+ECE+ CP CVN+ GSF+C CP G L GR C DV
Sbjct: 865 VTCDDVNECESFPGVCPNGRCVNTAGSFRCE-CPEGLMLDASGRLCVDVRLEPCFLRWDE 923
Query: 769 DECSSGAPPCGPHGHCTNTEGS---FRCSCAP---------------GYRAP---SGRPG 807
DEC P C + G+ C P G+ + SGRP
Sbjct: 924 DECGVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLGFASRDFLSGRPF 983
Query: 808 PCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECS-EEDLCQSG 866
DVNEC HG C NT GSF C CA G+ + +C D+DEC DLC G
Sbjct: 984 -YKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQG 1042
Query: 867 ICTNTDGSFECICPPGHRAGPDL-ASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCD 925
C NT GSFEC C PG+ +G L +C+DVDEC R P LC C N+ GSY+C C
Sbjct: 1043 TCVNTPGSFECECFPGYESGFMLMKNCMDVDEC-ARDPLLCRGGTCTNTDGSYKC--QCP 1099
Query: 926 PGYHAGPEGT-CDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPG-GGCQDV 983
PG+ +GT C+D+DEC +C +C N G+++C +C G+Q TP GC D+
Sbjct: 1100 PGHELTAKGTACEDIDEC-SLSDGLCPHGQCVNVIGAFQC--SCHAGFQSTPDRQGCVDI 1156
Query: 984 DECR-NRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCEN 1042
+ECR C H C N GS++C C QGY DGR C DV+ECE VC C N
Sbjct: 1157 NECRVQNGGCDVH--CINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTN 1214
Query: 1043 VEGSFLCVC 1051
+ G C+C
Sbjct: 1215 MPGGHRCLC 1223
Score = 287 bits (735), Expect = 5e-77
Identities = 274/958 (28%), Positives = 350/958 (36%), Gaps = 242/958 (25%)
Query: 467 WTGPEIPESGPSSGMCQRNPQVC-GPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECR 525
W G + +GP + +P + GP C SR Y C G+R P ++C+ V CR
Sbjct: 33 WDGA-LEAAGPGRVRRRGSPGILQGPNVCGSRFHAYCCP---GWRTFPGRSQCV-VPICR 87
Query: 526 RVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGR-------C 578
R CG GF + P C D + P C + R C
Sbjct: 88 RA-------------------CGEGFCSQPNLCTCAD----GTLAPSCGVSRGSGCSVSC 124
Query: 579 EN--TPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKN---LPGSFRCVCPA 633
N T C+C GY G C +C RG C N G RC C
Sbjct: 125 MNGGTCRGASCLCQKGYT----GTVC--------GQPICDRG-CHNGGRCIGPNRCACVY 171
Query: 634 GFRGSACEEDVDECAQEPPPC----GPGRCDNTAGSFHCA------------------CP 671
GF G CE D PC GP C + C CP
Sbjct: 172 GFMGPQCERD-----YRTGPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCP 226
Query: 672 A-------GFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSE 724
A GF CQDVDEC P C G C N GSF C CP+G + + + +
Sbjct: 227 AQPHPCRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAA 286
Query: 725 CEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPP---CGPH 781
CED C + +C +GH+ R C D C + P C P
Sbjct: 287 CEDY---------RAGACFSVLFGGRCAGDLAGHYTRRQCCCDRGRCWAAGPVPELCPPR 337
Query: 782 GHCTNTEGSFRCSCA------PGYRA--------------------------------PS 803
G F+ CA PG+ PS
Sbjct: 338 G-----SNEFQQLCAQRLPLLPGHPGLFPGLLGFGSNGMGPPLGPARLNPHGSDARGIPS 392
Query: 804 GRPG----PCADVNECLE-----GDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDV 854
PG A +N+ ++ + C +G CL T S+ C C GY RG C+DV
Sbjct: 393 LGPGNSNIGTATLNQTIDICRHFTNLCL-NGRCLPTPSSYRCECNVGYTQDVRG-ECIDV 450
Query: 855 DECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENS 914
DEC+ C G C N G++ C C PG +A P +C+DVDEC G LC RC N+
Sbjct: 451 DECTSSP-CHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSG-GLCHLGRCVNT 508
Query: 915 PGSYRCVRDCDPGYHAGPEG-TCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQ 973
GS++CV C+ G+ P+G C D +EC +C C N GS+ C C PG+
Sbjct: 509 EGSFQCV--CNAGFELSPDGKNCVDHNECAT--STMCVNGVCLNEDGSFSC--LCKPGFL 562
Query: 974 PTPGGG-CQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQ 1032
PGG C D+DEC+ C + C N GSF+C C G DGR CVD + T
Sbjct: 563 LAPGGHYCMDIDECQTPGIC-VNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCY 621
Query: 1033 GVCGAALCENVEGSFL----CVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVL 1088
G C + C C N F C P + SA + QA S L
Sbjct: 622 GAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLC-PAKDSA------EFQALCSSGL 674
Query: 1089 PARPPPPPLPRRPSTPRQGPVGSGR--RECYFDTAAPDACDNILARNVTWQ-ECCCTVGE 1145
G GR EC D P+ C N + N+ C C +
Sbjct: 675 ------------------GITTDGRDINECALD---PEVCANGVCENLRGSYRCVCNL-- 711
Query: 1146 GWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVN 1205
G+ +G + C DVDEC L +C +G C N
Sbjct: 712 GYEAGASGKDC----------------------------TDVDECAL-NSLLCDNGWCQN 742
Query: 1206 TAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGS 1265
+ YSC C G+++ C D DEC C G C N GSY C C P LD S
Sbjct: 743 SPGSYSCSCPPGFHFWQDTEICKDVDECLSS--PCVSGVCRNLAGSYTCKCGPGSRLDPS 800
Query: 1266 QRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLYGEAWGMDCALC 1323
C LD G CW ++ L + +ECC G AWG C C
Sbjct: 801 GTFC-------LDSTKGTCWLKIQESR--CEVNLQGASLRSECCATLGAAWGSPCERC 849
Score = 247 bits (630), Expect = 7e-65
Identities = 176/548 (32%), Positives = 224/548 (40%), Gaps = 54/548 (9%)
Query: 277 CPTGFER-VNGSCEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVI 335
C GFE + +CED+DEC+ C NT G Y C CP G+ L + C
Sbjct: 2152 CADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRDVDEC 2211
Query: 336 SEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGK----AWGRGC----------QLCP 381
++ + C R C +N+ C G G GC LC
Sbjct: 2212 ADGQQDCHA--RGMEC-----KNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCV 2264
Query: 382 PFG----SEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGF 437
+ FR C G + S + Q P + Q +S A
Sbjct: 2265 NGRCVNTAGSFRCDCDEG----FQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEA-- 2318
Query: 438 LPTHRLEPRPEPRPDPRPGPEL-PLPSIPAWT-----GPEIPESGPSSGMCQRNPQVCGP 491
R E P EL PLP A+ G G C+ +C
Sbjct: 2319 --VTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAH 2376
Query: 492 GRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGF 551
G CI+ + C C +G+ T C+D+DEC +VP PC C+N+ GSF C C G+
Sbjct: 2377 GECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCT-FLCKNTKGSFLCSCPRGY 2435
Query: 552 RAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQS 611
C D+DEC C C NT G+F C CP G+ H +C D DEC+
Sbjct: 2436 LLEEDGRTCKDLDECTSRQHNCQF-LCVNTVGAFTCRCPPGF--TQHHQACFDNDECSAQ 2492
Query: 612 PGLCG-RGACKNLPGSFRCVCPAGFR----GSACEEDVDECAQEPPPCGPGRCDNTAGSF 666
PG CG G C N PGSFRC C GF G CE DV+EC P C G C N G +
Sbjct: 2493 PGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCE-DVNEC-DGPHRCQHG-CQNQLGGY 2549
Query: 667 HCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECE 726
C+CP GF A C D +ECA SPP C C NT G F+CVCP GF + A C+
Sbjct: 2550 RCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQ 2609
Query: 727 DVDECENHLACPGQECVNSPGSFQCRTCPSGH-HLHRGRCTDVDECSSGAPPCGPHGHCT 785
+VDEC C N+PG F C CP G+ +G C S G
Sbjct: 2610 EVDECAGRRGPCSYSCANTPGGFLC-GCPQGYFRAGQGHCVSGLGFSPGPQDTPDKEELL 2668
Query: 786 NTEGSFRC 793
++E + C
Sbjct: 2669 SSEACYEC 2676
Score = 138 bits (348), Expect = 4e-32
Identities = 165/661 (24%), Positives = 213/661 (32%), Gaps = 202/661 (30%)
Query: 946 GPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRN---RSFCGAHAVCQNLP 1002
GP +CG+ R C PG++ PG V CR FC +C
Sbjct: 56 GPNVCGS----------RFHAYCCPGWRTFPGRSQCVVPICRRACGEGFCSQPNLCTCAD 105
Query: 1003 GSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCV--CPNSPEEFDP 1060
G+ C G+ C++ C +C V G +C C N
Sbjct: 106 GTLAPSCGVS-RGSGCSVSCMNGGTCRGASCLCQKGYTGTVCGQPICDRGCHNG------ 158
Query: 1061 MTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDT 1120
GRC+ P A + PQ R GP F
Sbjct: 159 --GRCIGPNRCACVYGFMGPQCERDY------------------RTGPC--------FGQ 190
Query: 1121 AAPDACDNILARNV-TWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSG 1179
P+ C + L V T CC TVG WG C + CP PH
Sbjct: 191 VGPEGCQHQLTGLVCTKALCCATVGRAWGLPCEL--CPAQ---------PHP-------- 231
Query: 1180 DLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPA 1239
C+ G N G C D DEC
Sbjct: 232 ------------------CRRGFIPNIHTG----------------ACQDVDECQAVPGL 257
Query: 1240 CEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRL 1299
C+GG CVN VGS+HC C L S C D G C+ + L
Sbjct: 258 CQGGSCVNMVGSFHCRCPVGHRLSDSSAACE-------DYRAGACFSVLFGGRCAGD--L 308
Query: 1300 DRQATYTECCCLYGEAW--GMDCALCPAQDSDDFEALCNVLRPPAYSPPRPGGFGLPYEY 1357
T +CCC G W G LCP + S++F+ LC P P PG F +
Sbjct: 309 AGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQLCAQRLP--LLPGHPGLFPGLLGF 366
Query: 1358 GPD-LGPPYQGLPYGPELYPPPALPYDPYPPPPGPFARREAPYGAPRFDMPDFEDDGGPY 1416
G + +GPP GP R P+G+ +P
Sbjct: 367 GSNGMGPPL------------------------GP--ARLNPHGSDARGIP--------- 391
Query: 1417 GESEAPAPPGPGTRWPYRSRDTRRSFPE----PEEPPEGGSYAGSLAEPYEELEAEECGI 1472
S P GT ++ D R F P SY Y + EC
Sbjct: 392 --SLGPGNSNIGTATLNQTIDICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGECID 449
Query: 1473 LDGCTN-----GRCVRVPEGFTCRCFDGYRLDMTRMACVDINEC---------------- 1511
+D CT+ G CV +P + CRC+ G++ TR ACVD++EC
Sbjct: 450 VDECTSSPCHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTE 509
Query: 1512 ---------------------DEAEAA-SPLCVNARCLNTDGSFRCICRPGFAPTHQPHH 1549
D E A S +CVN CLN DGSF C+C+PGF H+
Sbjct: 510 GSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHY 569
Query: 1550 C 1550
C
Sbjct: 570 C 570
Score = 134 bits (338), Expect = 5e-31
Identities = 186/715 (26%), Positives = 246/715 (34%), Gaps = 140/715 (19%)
Query: 661 NTAGS-FHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMG-FQP 718
N GS FH C G+R+ PG V C R+ C G C C C G P
Sbjct: 58 NVCGSRFHAYCCPGWRTF-PGRSQCVVPICRRA---CGEGFCSQPN---LCTCADGTLAP 110
Query: 719 N---TAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGA 775
+ + GS C C N C G C+ C G+ G C G
Sbjct: 111 SCGVSRGSGCSV--SCMNGGTCRGASCL----------CQKGY---TGTVCGQPICDRG- 154
Query: 776 PPCGPHGHCTNTEGSFRCSCAPGYRAPSG----RPGPC------ADVNECLEGDFCFPHG 825
C G C G RC+C G+ P R GPC L G C
Sbjct: 155 --CHNGGRCI---GPNRCACVYGFMGPQCERDYRTGPCFGQVGPEGCQHQLTGLVCTKAL 209
Query: 826 ECLNTDGSFACTCA----------PGYRPGPRGASCLDVDECSE-EDLCQSGICTNTDGS 874
C ++ C G+ P +C DVDEC LCQ G C N GS
Sbjct: 210 CCATVGRAWGLPCELCPAQPHPCRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGS 269
Query: 875 FECICPPGHRAGPDLASCLDVDECRERGPALCGSQ----RCENSPGSYRCVRDC--DPG- 927
F C CP GHR A+ C + C S RC + R C D G
Sbjct: 270 FHCRCPVGHRLSDSSAA------CEDYRAGACFSVLFGGRCAGDLAGHYTRRQCCCDRGR 323
Query: 928 -YHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGC-QDVDE 985
+ AGP E+ ++C AQR PG P PG G +
Sbjct: 324 CWAAGPVPELCPPRGSNEF-QQLC-AQRLPLLPGH----PGLFPGLLGFGSNGMGPPLGP 377
Query: 986 CR-NRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVE 1044
R N A + PG+ G +D+ C +C C
Sbjct: 378 ARLNPHGSDARGIPSLGPGNSNI-------GTATLNQTIDI--CRHFTNLCLNGRCLPTP 428
Query: 1045 GSFLCVCPNSPEEFDPMTGRC--VPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPS 1102
S+ C C + + G C V TS+ G P + P P R
Sbjct: 429 SSYRCECNVGYTQ--DVRGECIDVDECTSSPCHHGDCVNIPGTYHCRCYPGFQATPTR-- 484
Query: 1103 TPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETA 1162
AC ++ EC + G C + +C TE
Sbjct: 485 ---------------------QACVDV-------DECIVS-----GGLCHLGRCVNTE-G 510
Query: 1163 EYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHT 1222
+Q +C G L+P G + VD + +C +GVC+N +SC C G+
Sbjct: 511 SFQCVCNAGFE-LSPDG----KNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAP 565
Query: 1223 QRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLG 1282
C+D DEC C G C NT GS+ C C L + R CV +S
Sbjct: 566 GGHYCMDIDEC-QTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRS------ 618
Query: 1283 VCWQEVGADLVCSHPRLDRQATYTECCCLYGE-AWGMDCALCPAQDSDDFEALCN 1336
C+ + C+ P T +ECCC + +G C LCPA+DS +F+ALC+
Sbjct: 619 TCYGAIEKG-SCARP-FPGTVTKSECCCANPDHGFGEPCQLCPAKDSAEFQALCS 671
Score = 62.8 bits (151), Expect = 3e-09
Identities = 32/93 (34%), Positives = 42/93 (45%), Gaps = 4/93 (4%)
Query: 1465 LEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1524
++ EC C NG C+ F+C C G+ L C+DI+EC +CVN
Sbjct: 530 VDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQ----TPGICVNG 585
Query: 1525 RCLNTDGSFRCICRPGFAPTHQPHHCAPARPRA 1557
C NT+GSFRC C G A C R+
Sbjct: 586 HCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRS 618
Score = 58.5 bits (140), Expect = 5e-08
Identities = 56/220 (25%), Positives = 82/220 (37%), Gaps = 24/220 (10%)
Query: 185 VARAEAAARAEAAAPYTVLAQSAPREDGYSDASGFGYCFRELRGGECASP-LPGLRTQEV 243
+AR A A + +A R DG +A+G G R G P + G R
Sbjct: 8 LARGPLARLLLAWSALLCMAGGQGRWDGALEAAGPGRVRRRGSPGILQGPNVCGSRFHAY 67
Query: 244 CCRGAGLAWGVHDC------QLCSERLGNSERV-SAPDGPCPTGFERVNGSCEDVDECAT 296
CC G G C + C E + + + DG GS V C
Sbjct: 68 CCPGWRTFPGRSQCVVPICRRACGEGFCSQPNLCTCADGTLAPSCGVSRGSGCSVS-CMN 126
Query: 297 GGRCQHGECANTRGGYTCVCPD----------GFLLDSSRSSCISQHVISEAK-----GP 341
GG C+ C +G VC G + +R +C+ + + + GP
Sbjct: 127 GGTCRGASCLCQKGYTGTVCGQPICDRGCHNGGRCIGPNRCACVYGFMGPQCERDYRTGP 186
Query: 342 CFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCP 381
CF + GC + + + CC+ VG+AWG C+LCP
Sbjct: 187 CFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCP 226
Score = 55.8 bits (133), Expect = 3e-07
Identities = 31/94 (32%), Positives = 41/94 (43%), Gaps = 11/94 (11%)
Query: 1449 PEGGSYAGSLAEPYEELEAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVD 1507
P G Y E + +EC +L C +G C+ F C C GY D T C+D
Sbjct: 2352 PHGSGYTA------EGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLD 2405
Query: 1508 INECDEAEAASPLCVNARCLNTDGSFRCICRPGF 1541
++EC + P C NT GSF C C G+
Sbjct: 2406 MDECSQV----PKPCTFLCKNTKGSFLCSCPRGY 2435
Score = 52.4 bits (124), Expect = 3e-06
Identities = 28/76 (36%), Positives = 35/76 (46%), Gaps = 4/76 (5%)
Query: 1466 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNAR 1525
+ EC C +G C G+ C C G+ CVD NEC + P C +A
Sbjct: 2528 DVNECDGPHRCQHG-CQNQLGGYRCSCPQGFTQHSQWAQCVDENEC---ALSPPTCGSAS 2583
Query: 1526 CLNTDGSFRCICRPGF 1541
C NT G FRC+C GF
Sbjct: 2584 CRNTLGGFRCVCPSGF 2599
Score = 48.1 bits (113), Expect = 6e-05
Identities = 31/90 (34%), Positives = 38/90 (42%), Gaps = 6/90 (6%)
Query: 1465 LEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1524
L +E C L C R C G+ MT + C D+NEC E+ +C N
Sbjct: 830 LRSECCATLGAAWGSPCERCE--IDPACARGFAR-MTGVTCDDVNEC---ESFPGVCPNG 883
Query: 1525 RCLNTDGSFRCICRPGFAPTHQPHHCAPAR 1554
RC+NT GSFRC C G C R
Sbjct: 884 RCVNTAGSFRCECPEGLMLDASGRLCVDVR 913
Score = 42.7 bits (99), Expect = 0.003
Identities = 29/101 (28%), Positives = 41/101 (40%), Gaps = 8/101 (7%)
Query: 1449 PEGGSYAGSLAEPYEELEAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVD 1507
P+G + A+ +E EC + C + C GF C C G+ D C +
Sbjct: 2554 PQGFTQHSQWAQCVDE---NECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQE 2610
Query: 1508 INECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPH 1548
++EC A P + C NT G F C C G+ Q H
Sbjct: 2611 VDEC--AGRRGPCSYS--CANTPGGFLCGCPQGYFRAGQGH 2647
Score = 38.9 bits (89), Expect = 0.039
Identities = 14/34 (41%), Positives = 21/34 (61%)
Query: 1510 ECDEAEAASPLCVNARCLNTDGSFRCICRPGFAP 1543
+ DE + LC + C+N+ GSFRC C+ G+ P
Sbjct: 2363 DVDECRMLAHLCAHGECINSLGSFRCHCQAGYTP 2396
Score = 37.4 bits (85), Expect = 0.11
Identities = 29/94 (30%), Positives = 40/94 (42%), Gaps = 11/94 (11%)
Query: 1466 EAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1524
+ +EC + G C G CV + F CRC G+RL + AC D A A +
Sbjct: 247 DVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDY----RAGACFSVLFGG 302
Query: 1525 RCL-NTDGSF---RCICRPG--FAPTHQPHHCAP 1552
RC + G + +C C G +A P C P
Sbjct: 303 RCAGDLAGHYTRRQCCCDRGRCWAAGPVPELCPP 336
Score = 36.6 bits (83), Expect = 0.19
Identities = 21/66 (31%), Positives = 29/66 (43%), Gaps = 3/66 (4%)
Query: 1492 CFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHCA 1551
C G+ ++ AC D++EC +A LC C+N GSF C C G + C
Sbjct: 232 CRRGFIPNIHTGACQDVDEC---QAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACE 288
Query: 1552 PARPRA 1557
R A
Sbjct: 289 DYRAGA 294
Score = 36.2 bits (82), Expect = 0.25
Identities = 15/37 (40%), Positives = 19/37 (51%)
Query: 1474 DGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINE 1510
D C NGRCV F C C +G++ T C DI +
Sbjct: 2261 DLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQ 2297
Score = 32.0 bits (71), Expect = 4.8
Identities = 37/130 (28%), Positives = 47/130 (36%), Gaps = 24/130 (18%)
Query: 7 LLWVSLLVLLAQLGPQPGLGRLGERLRVRFT--------PVVCGLR----CVHG----PT 50
L W +LL + G G RVR P VCG R C G P
Sbjct: 18 LAWSALLCMAGGQGRWDGALEAAGPGRVRRRGSPGILQGPNVCGSRFHAYCCPGWRTFPG 77
Query: 51 GSRCT-PTCAPR------NATSVDSGAPGGAAPGGPGFRAFLCPLICHNGGVCVKPDRCL 103
S+C P C + ++ + A G AP R C + C NGG C + CL
Sbjct: 78 RSQCVVPICRRACGEGFCSQPNLCTCADGTLAPSCGVSRGSGCSVSCMNGGTC-RGASCL 136
Query: 104 CPPDFAGKFC 113
C + G C
Sbjct: 137 CQKGYTGTVC 146
>gi|18497288 latent transforming growth factor beta binding protein 3
isoform 2 [Homo sapiens]
Length = 1256
Score = 575 bits (1482), Expect = e-163
Identities = 412/1275 (32%), Positives = 547/1275 (42%), Gaps = 247/1275 (19%)
Query: 2 AGGVRLLWVSLLVLLAQLGPQPGLGRLGER------------LRVRFTPVVCGLRCVHGP 49
A G+ L + LL+LL LG + G GER +V F PV+C C+ G
Sbjct: 20 AAGLLALLLLLLLLLLGLGGRVEGGPAGERGAGGGGALARERFKVVFAPVICKRTCLKG- 78
Query: 50 TGSRCTPTCAP-RNATSVDSGAPGGAAPGGPGFRAFLCPLICHNGGVCVKPDRCLCPPDF 108
+C +C N T + G GFR +CPL C NGG C ++CLCPPDF
Sbjct: 79 ---QCRDSCQQGSNMTLIGENGHSTDTLTGSGFRVVVCPLPCMNGGQCSSRNQCLCPPDF 135
Query: 109 AGKFCQLHSSGAR---------------------------------------------PP 123
G+FCQ+ + GA PP
Sbjct: 136 TGRFCQVPAGGAGGGTGGSGPGLSRTGALSTGALPPLAPEGDSVASKHAIYAVQVIADPP 195
Query: 124 APAV-PGLTRSVYTMPLANHRDDEHGVAS--MVSVHVEHPQEASVVVHQVERVSGPWEEA 180
P P + + +PL + A +V+V V HP EASV VH++E
Sbjct: 196 GPGEGPPAQHAAFLVPLGPGQISAEVQAPPPVVNVRVHHPPEASVQVHRIES-------- 247
Query: 181 DAEAVARAEAAARAEAAAPYTVLAQSAPREDGYSDASGFGYCFRE-LRGGECAS-PLPGL 238
+ AE+AA ++ P+ + P G CF++ L C S PLPGL
Sbjct: 248 -----SNAESAAPSQHLLPHPKPSHPRPPTQ-----KPLGRCFQDTLPKQPCGSNPLPGL 297
Query: 239 RTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAP-----DGPCPTGFERVNGS-CEDVD 292
QE CC G AWG C C + + P CP G++R+N + C+D++
Sbjct: 298 TKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEVGADCPQGYKRLNSTHCQDIN 357
Query: 293 ECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLR-DGGC 351
ECA G C+HG+C N G Y CVCP G L SR+ CI+ E K CFR++ + C
Sbjct: 358 ECAMPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADK--PEEKSLCFRLVSPEHQC 415
Query: 352 SLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREICPAGPGYHY----------S 401
P+ +T+Q+CCCS VGKAWG CQ CP G+ F+EICPAG GYH
Sbjct: 416 QHPLTTRLTRQLCCCS-VGKAWGARCQRCPTDGTAAFKEICPAGKGYHILTSHQTLTIQG 474
Query: 402 ASDLRYNTRPLGQEPPRVSLSQPRTLP-----------ATSRPSAGFLPTHRLEPRPEPR 450
SD P G P+ P P T P + + P
Sbjct: 475 ESDFSLFLHPDGPPKPQQLPESPSQAPPPEDTEEERGVTTDSPVSEERSVQQSHPTATTT 534
Query: 451 PDPRPGPEL---PLPSIPAWTGPEIPESGPS----------SGMCQRNPQVCGPGRCISR 497
P RP PEL P P W P++P S + + C+ N +CG G C+
Sbjct: 535 P-ARPYPELISRPSPPTMRWFLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPG 593
Query: 498 PSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGR--CENSPGSFRCVCGPGFR--A 553
P Y+C C+ G+R PQ C+DV+EC PC PGR C N+ GS+ C C G+R
Sbjct: 594 PPDYSCHCNPGYRSHPQHRYCVDVNECE--AEPCGPGRGICMNTGGSYNCHCNRGYRLHV 651
Query: 554 GPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQ-AAPHGASCQDVDECTQSP 612
G C+D++EC + D G C N PG + C C GY+ A C+D+DEC + P
Sbjct: 652 GAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDEC-RDP 710
Query: 613 GLCGRGACKNLPGSFRCV-CPAGFR---GSACEEDVDECAQEPPPCGPGRCDNTAGSFHC 668
C G C+N PGSF+C+ C G+R G AC DV+ECA E PC PG C+N GSF C
Sbjct: 711 SSCPDGKCENKPGSFKCIACQPGYRSQGGGAC-RDVNECA-EGSPCSPGWCENLPGSFRC 768
Query: 669 ACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDV 728
C G+ G C DVDEC + C G C NT GSFQC C G+ + S CED+
Sbjct: 769 TCAQGYAPAPDGRSCLDVDEC-EAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDI 827
Query: 729 DECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGR-CTDVDECSSGAPPCGPHGHCTNT 787
DEC+ AC G +C+N+ GS++C CP GH L GR C D+DECS C PHG C N
Sbjct: 828 DECDFPAACIGGDCINTNGSYRC-LCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNL 886
Query: 788 EGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPH-GECLNTDGSFA-------CTCA 839
+GS+ C C G+ + G C +V + C+ + + + D A C C+
Sbjct: 887 QGSYVCVCDEGFTPTQDQHG-CEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCS 945
Query: 840 --------------PGYRPGPRGASC--------------------LDVDECS--EEDLC 863
P Y + C D+DEC ++C
Sbjct: 946 LGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEIC 1005
Query: 864 QSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRD 923
+ G C NT +EC C G +L C+DVDEC + + C + CEN+ G YRC
Sbjct: 1006 KEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDE--SNCRNGVCENTRGGYRCA-- 1061
Query: 924 CDPGYHAGP-EGTCDDVDECQEYGPE---ICGAQRCEN------------TPGSYRCTPA 967
C P P + C +E E PE +C +QR E+ T C
Sbjct: 1062 CTPPAEYSPAQRQCLSPEE-MERAPERRDVCWSQRGEDGMCAGPLAGPALTFDDCCCRQG 1120
Query: 968 CDPGYQ-----PTPGGGCQDVDECRNRSFCGAHAVCQNLP---------GSFQCLCDQGY 1013
G Q P G + + SF + P S +C C G
Sbjct: 1121 RGWGAQCRPCPPRGAGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECRCVSGR 1180
Query: 1014 EGARDG----------------RHCVDVNECETLQG---VCGAALCENVEGSFLCVCPNS 1054
R G CVD++EC L +C + C N GSF CVC
Sbjct: 1181 CVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAG 1240
Query: 1055 PEEFDPMTGRCVPPR 1069
P G CVP R
Sbjct: 1241 FARSRP-HGACVPQR 1254
Score = 472 bits (1215), Expect = e-132
Identities = 305/854 (35%), Positives = 391/854 (45%), Gaps = 131/854 (15%)
Query: 565 ECHRVPPPCDLGRCENTP--GSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKN 622
+CH+ P G + P G CP GY+ + CQD++EC PG+C G C N
Sbjct: 315 KCHKCPQLQYTGVQKPGPVRGEVGADCPQGYKRL-NSTHCQDINECAM-PGVCRHGDCLN 372
Query: 623 LPGSFRCVCPAGFR----GSACEEDVDE----CAQEPPP------------------CGP 656
PGS+RCVCP G + C D E C + P C
Sbjct: 373 NPGSYRCVCPPGHSLGPSRTQCIADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSV 432
Query: 657 G--------RC--DNTAGSFHCACPAG-----------------------FRSRGPGAPC 683
G RC D TA +F CPAG GP P
Sbjct: 433 GKAWGARCQRCPTDGTA-AFKEICPAGKGYHILTSHQTLTIQGESDFSLFLHPDGPPKPQ 491
Query: 684 QDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHL----ACPG 739
Q + +++PPP E+TE G ++ SE V + A P
Sbjct: 492 QLPESPSQAPPP------EDTEEE------RGVTTDSPVSEERSVQQSHPTATTTPARPY 539
Query: 740 QECVNSPGSFQCR-------TCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFR 792
E ++ P R S + + T+ DEC CG HG C +
Sbjct: 540 PELISRPSPPTMRWFLPDLPPSRSAVEIAPTQVTETDECRLNQNICG-HGECVPGPPDYS 598
Query: 793 CSCAPGYRA-PSGRPGPCADVNECLEGDFCFP-HGECLNTDGSFACTCAPGYR--PGPRG 848
C C PGYR+ P R C DVNEC E + C P G C+NT GS+ C C GYR G G
Sbjct: 599 CHCNPGYRSHPQHRY--CVDVNEC-EAEPCGPGRGICMNTGGSYNCHCNRGYRLHVGAGG 655
Query: 849 ASCLDVDECSEEDLC-QSGICTNTDGSFECICPPGHRAGPDLAS-CLDVDECRERGPALC 906
SC+D++EC++ LC G C N G ++C C PG+R C D+DECR+ P+ C
Sbjct: 656 RSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRD--PSSC 713
Query: 907 GSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTP 966
+CEN PGS++C+ C PGY + G C DV+EC E P C CEN PGS+RCT
Sbjct: 714 PDGKCENKPGSFKCIA-CQPGYRSQGGGACRDVNECAEGSP--CSPGWCENLPGSFRCT- 769
Query: 967 ACDPGYQPTPGG-GCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDV 1025
C GY P P G C DVDEC C + +C N PGSFQC C GY +RD HC D+
Sbjct: 770 -CAQGYAPAPDGRSCLDVDECEAGDVCD-NGICSNTPGSFQCQCLSGYHLSRDRSHCEDI 827
Query: 1026 NECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQA--- 1082
+EC+ C C N GS+ C+CP R V R SQ +
Sbjct: 828 DECD-FPAACIGGDCINTNGSYRCLCPQGH--------RLVGGRKCQDIDECSQDPSLCL 878
Query: 1083 PASPVLPARPPPPPLPRRPSTPRQGPVGSG-------RRECYFDTAAPDACDNILARNVT 1135
P + + TP Q G ++ECY + CD++LA NVT
Sbjct: 879 PHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVT 938
Query: 1136 WQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSG----DLSLRRDVDECQ 1191
QECCC++G GWG C I CP +AE+ SLCP G+GY + + RD+DEC
Sbjct: 939 QQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECM 998
Query: 1192 LFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGS 1251
LF ++CK G CVNT PGY CYC G+YY LEC+D DEC DE C G C NT G
Sbjct: 999 LFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDES-NCRNGVCENTRGG 1057
Query: 1252 YHCTCEPPLVLDGSQRRCVS-NESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCC 1310
Y C C PP +QR+C+S E + + VCW + G D +C+ P T+ +CCC
Sbjct: 1058 YRCACTPPAEYSPAQRQCLSPEEMERAPERRDVCWSQRGEDGMCAGPLAGPALTFDDCCC 1117
Query: 1311 LYGEAWGMDCALCP 1324
G WG C CP
Sbjct: 1118 RQGRGWGAQCRPCP 1131
Score = 345 bits (886), Expect = 1e-94
Identities = 244/734 (33%), Positives = 311/734 (42%), Gaps = 123/734 (16%)
Query: 604 DVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEE---DVDECAQEPPPCGPGR-- 658
+ DEC + +CG G C P + C C G+R DV+EC EP CGPGR
Sbjct: 574 ETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEP--CGPGRGI 631
Query: 659 CDNTAGSFHCACPAGFRSR--GPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGF 716
C NT GS++C C G+R G C D++ECA+ G C N G ++C C G+
Sbjct: 632 CMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGY 691
Query: 717 QPNTAGSE-CEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRG-RCTDVDECSSG 774
+ + CED+DEC + +CP +C N PGSF+C C G+ G C DV+EC+ G
Sbjct: 692 RLKASRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGYRSQGGGACRDVNECAEG 751
Query: 775 APPCGPHGHCTNTEGSFRCSCAPGYR-APSGRPGPCADVNECLEGDFCFPHGECLNTDGS 833
+P C P G C N GSFRC+CA GY AP GR C DV+EC GD C +G C NT GS
Sbjct: 752 SP-CSP-GWCENLPGSFRCTCAQGYAPAPDGRS--CLDVDECEAGDVC-DNGICSNTPGS 806
Query: 834 FACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCL 893
F C C GY + C D+DEC C G C NT+GS+ C+CP GHR C
Sbjct: 807 FQCQCLSGYHLSRDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGG-RKCQ 865
Query: 894 DVDECRERGPALCGSQ-RCENSPGSYRCVRDCDPGY------HAGPEGT----------- 935
D+DEC + P+LC C+N GSY CV CD G+ H E
Sbjct: 866 DIDECSQ-DPSLCLPHGACKNLQGSYVCV--CDEGFTPTQDQHGCEEVEQPHHKKECYLN 922
Query: 936 ------CDDVDECQEYGPEIC---GA---QRCENTP----GSYRCTPACDPGYQPTPGGG 979
CD V E C GA CE P S C G T
Sbjct: 923 FDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNN 982
Query: 980 C--------QDVDECR--NRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECE 1029
+D+DEC C C N ++C C QG+ + CVDV+EC
Sbjct: 983 IVNYGIPAHRDIDECMLFGSEIC-KEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECL 1041
Query: 1030 TLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLP 1089
+ C +CEN G + C C P E+ P +C+ P
Sbjct: 1042 D-ESNCRNGVCENTRGGYRCAC-TPPAEYSPAQRQCLSPEE------------------- 1080
Query: 1090 ARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARN-VTWQECCCTVGEGWG 1148
+ R P R C+ C LA +T+ +CCC G GWG
Sbjct: 1081 -------MERAPER---------RDVCWSQRGEDGMCAGPLAGPALTFDDCCCRQGRGWG 1124
Query: 1149 SGCRI-------QQCPGTETAEYQSLCPHGRGYLA--PSGDLSLRRDVDECQLFRDQVCK 1199
+ CR CP T +E S L P + S D DEC+ C
Sbjct: 1125 AQCRPCPPRGAGSHCP-TSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECR------CV 1177
Query: 1200 SGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEP---ACEGGRCVNTVGSYHCTC 1256
SG CV G C C G+ R C+D DEC + C+ RCVNT GS+ C C
Sbjct: 1178 SGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVC 1237
Query: 1257 EPPLVLDGSQRRCV 1270
+ CV
Sbjct: 1238 KAGFARSRPHGACV 1251
Score = 211 bits (537), Expect = 4e-54
Identities = 213/772 (27%), Positives = 290/772 (37%), Gaps = 157/772 (20%)
Query: 853 DVDECS-EEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRC 911
+ DEC +++C G C + C C PG+R+ P C+DV+EC E P G C
Sbjct: 574 ETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNEC-EAEPCGPGRGIC 632
Query: 912 ENSPGSYRCVRDCDPGY--HAGPEG-TCDDVDECQEYGPEICG-AQRCENTPGSYRCTPA 967
N+ GSY C C+ GY H G G +C D++EC + P +CG C N PG Y+C
Sbjct: 633 MNTGGSYNC--HCNRGYRLHVGAGGRSCVDLNECAK--PHLCGDGGFCINFPGHYKCN-- 686
Query: 968 CDPGYQPTPGGG--CQDVDECRNRSFCGAHAVCQNLPGSFQCL-CDQGYEGARDGRHCVD 1024
C PGY+ C+D+DECR+ S C C+N PGSF+C+ C GY ++ G C D
Sbjct: 687 CYPGYRLKASRPPVCEDIDECRDPSSC-PDGKCENKPGSFKCIACQPGYR-SQGGGACRD 744
Query: 1025 VNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPA 1084
VNEC C CEN+ GSF C C +Q APA
Sbjct: 745 VNECAE-GSPCSPGWCENLPGSFRCTC--------------------------AQGYAPA 777
Query: 1085 SPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYF--DTAAPDACDNILARNVTWQ-ECCC 1141
P G R C + A D CDN + N +C C
Sbjct: 778 -----------------------PDG---RSCLDVDECEAGDVCDNGICSNTPGSFQCQC 811
Query: 1142 TVGE---------------GWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRD 1186
G + + C C T Y+ LCP G + +D
Sbjct: 812 LSGYHLSRDRSHCEDIDECDFPAACIGGDCINTN-GSYRCLCPQGHRLVGGRKC----QD 866
Query: 1187 VDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDND------ECA---DEE 1237
+DEC G C N Y C C G+ + C + + EC D+
Sbjct: 867 IDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDT 926
Query: 1238 PACEG--------GRCVNTVGSY---HCTCEPPLVLDGSQRR--CVSNESQSLDDNLGVC 1284
C+ C ++G+ HC P V ++ C + + D+N+
Sbjct: 927 VFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNY 986
Query: 1285 WQEVGADL---------VCSHPRLDRQATYTECCCLYGEAWGMDCALCPAQDSDDFEALC 1335
D+ +C + EC C G + + C D E+ C
Sbjct: 987 GIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNC 1046
Query: 1336 NVLRPPAYSPPRPGGFGL----PYEYGPDLGPPYQGLPYGPELYPPPALPYDPYPPPPGP 1391
GG+ P EY P Q PE D G
Sbjct: 1047 R----NGVCENTRGGYRCACTPPAEYSPA-----QRQCLSPEEMERAPERRDVCWSQRGE 1097
Query: 1392 FARREAPYGAPRFDMPDFE-DDGGPYGESEAPAPP-GPGTRWPYRSRDTRRSFPEPE--- 1446
P P D G +G P PP G G+ P S+ SF +
Sbjct: 1098 DGMCAGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSHCP-TSQSESNSFWDTSPLL 1156
Query: 1447 --EPPEGGSYAGSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMA 1504
+PP E E +++EC C +GRCV P G C C G++LD +R
Sbjct: 1157 LGKPPRD--------EDSSEEDSDECR----CVSGRCVPRPGGAVCECPGGFQLDASRAR 1204
Query: 1505 CVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHCAPARPR 1556
CVDI+EC E LC + RC+NT GSFRC+C+ GFA + C P R R
Sbjct: 1205 CVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGACVPQRRR 1256
Score = 166 bits (420), Expect = 2e-40
Identities = 183/672 (27%), Positives = 246/672 (36%), Gaps = 131/672 (19%)
Query: 754 CPSGH-HLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADV 812
CP G+ L+ C D++EC+ P HG C N GS+RC C PG+ R AD
Sbjct: 341 CPQGYKRLNSTHCQDINECAM--PGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADK 398
Query: 813 NECLEGDFCF----PHGECLNTDGSFA----CTCAPGYRPGPRGASCLDVDECSEEDLCQ 864
E E CF P +C + + C C+ G G R C + +++C
Sbjct: 399 PE--EKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQRCPTDGTAAFKEICP 456
Query: 865 SGICTNTDGSFECICPPG--------HRAGPDLASCLDVDECRERGPALCGSQR--CENS 914
+G + S + + G H GP L + P +R +S
Sbjct: 457 AGKGYHILTSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSQAPPPEDTEEERGVTTDS 516
Query: 915 PGSY-RCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQ 973
P S R V+ P P + Y PE+ + P P P
Sbjct: 517 PVSEERSVQQSHPTATTTP---------ARPY-PELISRP---SPPTMRWFLPDLPPSRS 563
Query: 974 PTPGGGCQ--DVDECR-NRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECET 1030
Q + DECR N++ CG H C P + C C+ GY R+CVDVNECE
Sbjct: 564 AVEIAPTQVTETDECRLNQNICG-HGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEA 622
Query: 1031 LQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGR-------CVPPRTSAG-----TFPGS 1078
G +C N GS+ C C GR C P FPG
Sbjct: 623 EPCGPGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGH 682
Query: 1079 QP--QAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDA-CDNILARNVT 1135
P + +RP PV EC ++ PD C+N + +
Sbjct: 683 YKCNCYPGYRLKASRP---------------PVCEDIDECRDPSSCPDGKCEN---KPGS 724
Query: 1136 WQECCCTVG---EGWGSGCRIQQC-------PG-TETAEYQSLCPHGRGYLAPSGDLSLR 1184
++ C G +G G+ + +C PG E C +GY AP+ D
Sbjct: 725 FKCIACQPGYRSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGY-APAPDGRSC 783
Query: 1185 RDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGR 1244
DVDEC+ VC +G+C NT + C C +GY+ R C D DEC D AC GG
Sbjct: 784 LDVDECE--AGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDEC-DFPAACIGGD 840
Query: 1245 CVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNL----GVCWQEVGA---------- 1290
C+NT GSY C C L G R+C + S D +L G C G+
Sbjct: 841 CINTNGSYRCLCPQGHRLVGG-RKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFT 899
Query: 1291 -------------------------DLVCSHPRLDRQATYTECCCLYGEAWGMDCAL--C 1323
D V L T ECCC G WG C + C
Sbjct: 900 PTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPC 959
Query: 1324 PAQDSDDFEALC 1335
P S +F +LC
Sbjct: 960 PVYSSAEFHSLC 971
Score = 139 bits (351), Expect = 2e-32
Identities = 125/460 (27%), Positives = 170/460 (36%), Gaps = 85/460 (18%)
Query: 1094 PPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCC-TVGEGWGSGCR 1152
P P P P P Q P+G C+ DT C + +T QE CC ++G WG +
Sbjct: 261 PHPKPSHPRPPTQKPLG----RCFQDTLPKQPCGSNPLPGLTKQEDCCGSIGTAWGQS-K 315
Query: 1153 IQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSC 1212
+CP + Q P +R +V
Sbjct: 316 CHKCPQLQYTGVQKPGP-------------VRGEV-----------------------GA 339
Query: 1213 YCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSN 1272
C GY C D +ECA C G C+N GSY C C P L S+ +C+++
Sbjct: 340 DCPQGYK-RLNSTHCQDINECA-MPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIAD 397
Query: 1273 ESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLYGEAWGMDCALCPAQDSDDFE 1332
+ + +C++ V + C HP L + T CCC G+AWG C CP + F+
Sbjct: 398 KPEEKS----LCFRLVSPEHQCQHP-LTTRLTRQLCCCSVGKAWGARCQRCPTDGTAAFK 452
Query: 1333 ALCNV-----LRPPAYSPPRPGGFGLPYEYGPDLGPPYQGLPYGPELYPPPALPYDPYPP 1387
+C + + G PD P Q LP P PPP
Sbjct: 453 EICPAGKGYHILTSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSQAPPP--------- 503
Query: 1388 PPGPFARREAPYGAPRFDMPDFEDDGGPYGESEAPAPPGPGTRWPYRSRDTRRSFPE--- 1444
E G D P E+ A P PY +R S P
Sbjct: 504 -----EDTEEERGVTT-DSPVSEERSVQQSHPTATTTPAR----PYPELISRPSPPTMRW 553
Query: 1445 --PEEPPEGGSYAGSLAEPYEELEAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMT 1501
P+ PP S + P + E +EC + C +G CV P ++C C GYR
Sbjct: 554 FLPDLPP---SRSAVEIAPTQVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQ 610
Query: 1502 RMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGF 1541
CVD+NEC EAE P C+NT GS+ C C G+
Sbjct: 611 HRYCVDVNEC-EAEPCGP--GRGICMNTGGSYNCHCNRGY 647
Score = 52.4 bits (124), Expect = 3e-06
Identities = 63/219 (28%), Positives = 82/219 (37%), Gaps = 36/219 (16%)
Query: 1358 GPDLGPPYQG----LPYGPELY------PPPALPYDPYPPPPGPFARREAPYGAPRFDMP 1407
GP GPP Q +P GP PPP + + PP EA R +
Sbjct: 196 GPGEGPPAQHAAFLVPLGPGQISAEVQAPPPVVNVRVHHPP-------EASVQVHRIESS 248
Query: 1408 DFEDDGGPYGESEAPAP--PGPGTRWPYRS--RDTRRSFPEPEEPPEG----GSYAGSLA 1459
+ E P P P P T+ P +DT P P G GS+
Sbjct: 249 NAESAAPSQHLLPHPKPSHPRPPTQKPLGRCFQDTLPKQPCGSNPLPGLTKQEDCCGSIG 308
Query: 1460 EPYEELEAEECGILD--GCTNGRCVRVPEGFTCRCFDGY-RLDMTRMACVDINECDEAEA 1516
+ + + +C L G VR G C GY RL+ T C DINEC A
Sbjct: 309 TAWGQSKCHKCPQLQYTGVQKPGPVRGEVGADCP--QGYKRLNSTH--CQDINEC----A 360
Query: 1517 ASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHCAPARP 1555
+C + CLN GS+RC+C PG + C +P
Sbjct: 361 MPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADKP 399
>gi|24430141 fibrillin 1 precursor [Homo sapiens]
Length = 2871
Score = 539 bits (1388), Expect = e-153
Identities = 369/1095 (33%), Positives = 491/1095 (44%), Gaps = 137/1095 (12%)
Query: 514 QGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDV---------- 563
+GT+C D+DEC P C G C N+ GSF+C C G CLD+
Sbjct: 904 KGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYE 963
Query: 564 -DEC-------HRVPPPC-------DLGRCE-----NTPGSFLCVCPAGYQAAPHGAS-- 601
+EC HR+ C CE NTP + +CP G A +
Sbjct: 964 DEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTP-EYEELCPRGPGFATKEITNG 1022
Query: 602 ---CQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEE---DVDECAQEPPPCG 655
+D++EC P LC G C+N GSF+C C +GF + E D+DEC P CG
Sbjct: 1023 KPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCG 1082
Query: 656 PGRCDNTAGSFHCACPAGFRSRGPGAP-CQDVDECARSPPPCTYGRCENTEGSFQCVCPM 714
G+C NT G F C C G+ S C D+DEC R P C G C NTEGS++C CP
Sbjct: 1083 RGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPP 1142
Query: 715 GFQPNTAGSECEDVDECE--NHLACPGQECVNSPGSFQCRTCPSGHHLHRGR--CTDVDE 770
G Q + S C D++ECE HL CP CVN G +QC C G+H R C D+DE
Sbjct: 1143 GHQLSPNISACIDINECELSAHL-CPNGRCVNLIGKYQC-ACNPGYHSTPDRLFCVDIDE 1200
Query: 771 CSSGAPPCGPHGHCTNTEGSFRCSCAPGYRA-PSGRPGPCADVNECLEGDFCFPHGECLN 829
CS C CTN+EGS+ CSC PG+ P R C D++EC + G+C N
Sbjct: 1201 CSIMNGGC--ETFCTNSEGSYECSCQPGFALMPDQRS--CTDIDECEDNPNICDGGQCTN 1256
Query: 830 TDGSFACTCAPGYRPGPRGASCLDVDECS-EEDLCQSGICTNTDGSFECICPPGHRAGPD 888
G + C C G+ +C+DV+EC ++C SG C NT GSF C C G+
Sbjct: 1257 IPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKG 1316
Query: 889 LASCLDVDECRERGPALCGSQR-CENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGP 947
C D++EC E G CG C N+ GS++C C PG+ G C D+DEC G
Sbjct: 1317 KTGCTDINEC-EIGAHNCGKHAVCTNTAGSFKC--SCSPGW-IGDGIKCTDLDECSN-GT 1371
Query: 948 EICGAQR-CENTPGSYRCTPACDPGYQPTPGGGCQDVDEC-RNRSFCGAHAVCQNLPGSF 1005
+C C+NT GSYRC C GY G C D+DEC N + CG + C N PG +
Sbjct: 1372 HMCSQHADCKNTMGSYRCL--CKEGYTGD-GFTCTDLDECSENLNLCG-NGQCLNAPGGY 1427
Query: 1006 QCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRC 1065
+C CD G+ + DG+ C D++EC +L +C C N+ G F C C E D G C
Sbjct: 1428 RCECDMGFVPSADGKACEDIDEC-SLPNICVFGTCHNLPGLFRCECEIG-YELDRSGGNC 1485
Query: 1066 ------VPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFD 1119
+ P T G+ P S + PP P+ R G V + CY D
Sbjct: 1486 TDVNECLDPTTCIS---GNCVNTPGSYICDC---PPDFELNPT--RVGCVDTRSGNCYLD 1537
Query: 1120 TA-----APDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGY 1174
AC N + V+ CCC++G+ WG+ C + CP T+EY+ LCP G G+
Sbjct: 1538 IRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPC--EMCPAVNTSEYKILCPGGEGF 1595
Query: 1175 LAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECA 1234
P+ + D+DECQ +C+ G C+NT + C C GYY + C D +EC
Sbjct: 1596 -RPNPITVILEDIDECQELPG-LCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNEC- 1652
Query: 1235 DEEPA-CEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLV 1293
E P C G C NTVG+Y C C P + C +D +C++ AD
Sbjct: 1653 -ETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNC-------MDMRRSLCYRNYYADNQ 1704
Query: 1294 CSHPRLDRQATYTECCCLY--GEAWGMDCALCPAQDSDDFEALCNVLRPPAYSPPRPGGF 1351
L T CCC Y G AW C CP +D+F LC RP GF
Sbjct: 1705 TCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRP---------GF 1755
Query: 1352 GLPYEYGPDLGPPYQGLPYG-PELYPPPALPYDPYPPPPGPFARREAPYGAPRFDMPDFE 1410
+ Y GLP E P + + R E P G F
Sbjct: 1756 VIDI---------YTGLPVDIDECREIPGVCENGVCINMVGSFRCECPVGF-------FY 1799
Query: 1411 DDGGPYGESEAPAPPGPGTRWPYRSRDTRRSFPEPEEPPEGGSYAGSLAEPYEELEAEEC 1470
+D E GP + +T S+ +P G S + + E +E
Sbjct: 1800 NDKLLVCEDIDECQNGPVCQRNAECINTAGSYRCDCKP---GYRFTSTGQCNDRNECQE- 1855
Query: 1471 GILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTD 1530
I + C++G+C+ F C C G++ + + C+DINEC+ C N C NT
Sbjct: 1856 -IPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECER-----DACGNGTCRNTI 1909
Query: 1531 GSFRCICRPGFAPTH 1545
GSF C C GF +H
Sbjct: 1910 GSFNCRCNHGFILSH 1924
Score = 478 bits (1230), Expect = e-134
Identities = 412/1505 (27%), Positives = 557/1505 (37%), Gaps = 299/1505 (19%)
Query: 222 CFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGP----- 276
CF EC P+ G + CC G AWG +C+ C R P GP
Sbjct: 958 CFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATK 1017
Query: 277 -------------------------------------CPTGF--ERVNGSCEDVDECATG 297
C +GF + +C D+DEC
Sbjct: 1018 EITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRIS 1077
Query: 298 -GRCQHGECANTRGGYTCVCPD----GFLLDSSR---SSCISQHVISEAKGPCFRVLRDG 349
C G+C NT G + C C + GF++ + C ++ G C
Sbjct: 1078 PDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRG-GVCHNTEGSY 1136
Query: 350 GCSLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGF--REICPAGPGYHYSASDLRY 407
C P ++ I C + + LCP + C PGY +S D +
Sbjct: 1137 RCECPPGHQLSPNISACIDINEC-ELSAHLCPNGRCVNLIGKYQCACNPGY-HSTPDRLF 1194
Query: 408 NTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAW 467
V + + + G T +PG L +P +
Sbjct: 1195 C----------VDIDECSIMN-------GGCETFCTNSEGSYECSCQPGFAL-MPDQRSC 1236
Query: 468 TGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRV 527
T +I E C+ NP +C G+C + P Y C C GF S C+DV+EC
Sbjct: 1237 T--DIDE-------CEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLN 1287
Query: 528 PPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGR-CENTPGSFL 586
P C G CEN+ GSF C C G+ C D++EC C C NT GSF
Sbjct: 1288 PNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFK 1347
Query: 587 CVCPAGYQAAPHGASCQDVDECTQSPGLCGRGA-CKNLPGSFRCVCPAGFRGSACE-EDV 644
C C G+ G C D+DEC+ +C + A CKN GS+RC+C G+ G D+
Sbjct: 1348 CSCSPGWIG--DGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCTDL 1405
Query: 645 DECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENT 704
DEC++ CG G+C N G + C C GF G C+D+DEC+ P C +G C N
Sbjct: 1406 DECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSL-PNICVFGTCHNL 1464
Query: 705 EGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGR 764
G F+C C +G++ + +G C DV+EC + C CVN+PGS+ C CP L+ R
Sbjct: 1465 PGLFRCECEIGYELDRSGGNCTDVNECLDPTTCISGNCVNTPGSYIC-DCPPDFELNPTR 1523
Query: 765 CTDVD----ECSSGAPPCGPHGH--CTNTEG----SFRCSCAPG---------------- 798
VD C P G +G C+N G C C+ G
Sbjct: 1524 VGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTS 1583
Query: 799 -YR--APSG---RPGPCA----DVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRG 848
Y+ P G RP P D++EC E G+C+NT GSF C C GY
Sbjct: 1584 EYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDT 1643
Query: 849 ASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGS 908
C DV+EC +C G C NT G++ CICPP + +C+D+ +
Sbjct: 1644 RVCDDVNECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADN 1703
Query: 909 QRCENSPGSYRCVRDCDPGYHAG----------PEGTCD--------------------- 937
Q C+ + C Y+ G P + D
Sbjct: 1704 QTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGL 1763
Query: 938 --DVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGG-GCQDVDECRNRSFCGA 994
D+DEC+E P +C C N GS+RC C G+ C+D+DEC+N C
Sbjct: 1764 PVDIDECREI-PGVCENGVCINMVGSFRCE--CPVGFFYNDKLLVCEDIDECQNGPVCQR 1820
Query: 995 HAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNS 1054
+A C N GS++C C GY G+ C D NEC+ + +C C + GSF C+C
Sbjct: 1821 NAECINTAGSYRCDCKPGYRFTSTGQ-CNDRNECQEIPNICSHGQCIDTVGSFYCLCHTG 1879
Query: 1055 PEEFDPMT-----GRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPV 1109
+ D T C GT + +
Sbjct: 1880 FKTNDDQTMCLDINECERDACGNGTC------------------------------RNTI 1909
Query: 1110 GSGRRECYFDTAAPDACDNILARN---VTWQECCCTVGEGWGSGCRIQQCPGTETAEYQS 1166
GS C IL+ N + EC G G+ CR QC T +Q
Sbjct: 1910 GSFNCRCNHGF--------ILSHNNDCIDVDECA----SGNGNLCRNGQCINT-VGSFQC 1956
Query: 1167 LCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLE 1226
C G +AP G + D++EC L + C G C N Y C C GY ++
Sbjct: 1957 QCNEGYE-VAPDGRTCV--DINEC-LLEPRKCAPGTCQNLDGSYRCICPPGYSLQNEK-- 2010
Query: 1227 CIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQ 1286
C D DEC +E C G C NT GS+ C C L S RRC D + C+
Sbjct: 2011 CEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRC-------QDLRMSYCYA 2063
Query: 1287 EVGADLVCSHPRLDRQATYTECCC-LYGEAWGMDCALCPAQDSDDFEALCNVLRPPAYSP 1345
+ CS P+ R + ECCC L GE WG C LCP + + F +C
Sbjct: 2064 KFEGG-KCSSPK-SRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQIC---------- 2111
Query: 1346 PRPGGFGLPYEYGPDLGPPYQGLPYGPELYPPPALPYDPYPPPPGPFARREAPYGAPRFD 1405
PY G +GP + E P + G + R E P+G
Sbjct: 2112 --------PYGSGIIVGPDDSAVDM-DECKEPDVCKHGQCINTDGSY-RCECPFGYILAG 2161
Query: 1406 MPDFEDD----GGPYGES-------------EAPAPPGPGTRWPYRSRDTRRSFPEPEEP 1448
+ D G P G E PGP T E +
Sbjct: 2162 NECVDTDECSVGNPCGNGTCKNVIGGFECTCEEGFEPGP--------MMTCEDINECAQN 2213
Query: 1449 P---------EGGSYAGSLAEPYEELEAEE-CGILDGCTNGR---------CVRVPEGFT 1489
P GSY Y E C D C G+ C + +
Sbjct: 2214 PLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYM 2273
Query: 1490 CRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHH 1549
C C GY+ CVD NEC + +C N RCLNT GS+ C C GF +
Sbjct: 2274 CICGPGYQRRPDGEGCVDENEC---QTKPGICENGRCLNTRGSYTCECNDGFTASPNQDE 2330
Query: 1550 CAPAR 1554
C R
Sbjct: 2331 CLDNR 2335
Score = 473 bits (1216), Expect = e-133
Identities = 374/1333 (28%), Positives = 512/1333 (38%), Gaps = 304/1333 (22%)
Query: 222 CFRELRGGECASPLPGLRTQ-EVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGP---- 276
C+ + G+C PL G T+ E CC A+G CQ C + + GP
Sbjct: 661 CYGGYKRGQCIKPLFGAVTKSECCCASTEYAFG-EPCQPCPAQNSAEYQALCSSGPGMTS 719
Query: 277 --------------CPTGF-ERVNGS-----------------CEDVDECATGGR-CQHG 303
CP G E + G+ C D++EC C +G
Sbjct: 720 AGSDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNG 779
Query: 304 ECANTRGGYTCVCPDGFL----------LDSSRSS-----------------CISQHV-- 334
+C NT G + C CP GF+ +D SS C S+
Sbjct: 780 QCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPCINGVCKNSPGSFICECSSESTLD 839
Query: 335 ------ISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCP--PFGSE 386
I KG C++ + DG C + I T + CCS +G AWG C LC P +
Sbjct: 840 PTKTICIETIKGTCWQTVIDGRCEINI-NGATLKSQCCSSLGAAWGSPCTLCQVDPICGK 898
Query: 387 GFREI----------CPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSR---- 432
G+ I C PG + L NTR + TL AT R
Sbjct: 899 GYSRIKGTQCEDIDECEVFPGV--CKNGLCVNTRGSF----KCQCPSGMTLDATGRICLD 952
Query: 433 -----------------PSAGFLPTHRL-------------EPRPEPRPDPRPGPELPLP 462
P AG HR+ E E P E P
Sbjct: 953 IRLETCFLRYEDEECTLPIAG---RHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCP 1009
Query: 463 SIPAWTGPEIPESGP---SSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCI 519
P + EI P C+ P +C G+C + + C CDSGF L + C
Sbjct: 1010 RGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCT 1069
Query: 520 DVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAG-PRAAECLDVDECHRVPPPCDLGRC 578
D+DECR P C G+C N+PG F C C G+ +G C+D+DEC R P C G C
Sbjct: 1070 DIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVC 1129
Query: 579 ENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGS 638
NT GS+ C CP G+Q +P+ ++C D++EC S LC G C NL G ++C C G+ +
Sbjct: 1130 HNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHST 1189
Query: 639 -----------------ACEE---------------------------DVDECAQEPPPC 654
CE D+DEC P C
Sbjct: 1190 PDRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNIC 1249
Query: 655 GPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPM 714
G+C N G + C C GF + C DV+EC +P C G CENT+GSF C C M
Sbjct: 1250 DGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDM 1309
Query: 715 GFQPNTAGSECEDVDECE--NHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECS 772
G+ + C D++ECE H C N+ GSF+C +C G +CTD+DECS
Sbjct: 1310 GYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKC-SCSPGWIGDGIKCTDLDECS 1368
Query: 773 SGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDG 832
+G C H C NT GS+RC C GY +G C D++EC E +G+CLN G
Sbjct: 1369 NGTHMCSQHADCKNTMGSYRCLCKEGY---TGDGFTCTDLDECSENLNLCGNGQCLNAPG 1425
Query: 833 SFACTCAPGYRPGPRGASCLDVDECSEEDLCQ---------------------------- 864
+ C C G+ P G +C D+DECS ++C
Sbjct: 1426 GYRCECDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNC 1485
Query: 865 -------------SGICTNTDGSFECICPPGHRAGPDLASC---------LDVDECRERG 902
SG C NT GS+ C CPP P C LD+ + G
Sbjct: 1486 TDVNECLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNG 1545
Query: 903 PALCGSQ--------------------RCENSPG----SYRCVRDCDPGYHAGPEGTC-D 937
C ++ CE P Y+ + G+ P +
Sbjct: 1546 DTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILE 1605
Query: 938 DVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGG-CQDVDECRNRSFCGAHA 996
D+DECQE P +C +C NT GS++C C GY C DV+EC CG
Sbjct: 1606 DIDECQEL-PGLCQGGKCINTFGSFQCR--CPTGYYLNEDTRVCDDVNECETPGICGP-G 1661
Query: 997 VCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQG------VCGAALCENVEGSFLCV 1050
C N G++ C+C Y G +C+D+ + C L N+ C
Sbjct: 1662 TCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCC 1721
Query: 1051 CPNSPEEFDPMTGRCVPPRTSA-GTFPGSQPQAPASPVLPARPPPPPLPRR-PSTPRQGP 1108
N ++ +C P T T GSQ + P R P G
Sbjct: 1722 SYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCENGV 1781
Query: 1109 ----VGSGRREC---YFDTAAPDACDNILARNVTWQECCCTVGEGWGSGC-RIQQCPGTE 1160
VGS R EC +F C++I EC G C R +C T
Sbjct: 1782 CINMVGSFRCECPVGFFYNDKLLVCEDI-------DECQN------GPVCQRNAECINT- 1827
Query: 1161 TAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYY 1220
Y+ C G + + +G + D +ECQ + +C G C++T + C C G+
Sbjct: 1828 AGSYRCDCKPGYRFTS-TGQCN---DRNECQEIPN-ICSHGQCIDTVGSFYCLCHTGFKT 1882
Query: 1221 HTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDN 1280
+ + C+D +EC E AC G C NT+GS++C C +L + +E S + N
Sbjct: 1883 NDDQTMCLDINEC--ERDACGNGTCRNTIGSFNCRCNHGFILSHNNDCIDVDECASGNGN 1940
Query: 1281 L---GVCWQEVGA 1290
L G C VG+
Sbjct: 1941 LCRNGQCINTVGS 1953
Score = 458 bits (1179), Expect = e-128
Identities = 343/1201 (28%), Positives = 497/1201 (41%), Gaps = 255/1201 (21%)
Query: 220 GYCFRELR----GGE--CASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAP 273
G C+ ++R G+ C++ + ++ CC G AWG C++C + ++ P
Sbjct: 1532 GNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGT-PCEMCPAVNTSEYKILCP 1590
Query: 274 DGP---------------------------------------CPTGFERVNGS--CEDVD 292
G CPTG+ + C+DV+
Sbjct: 1591 GGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVN 1650
Query: 293 ECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFR--VLRDGG 350
EC T G C G C NT G YTC+CP ++ + ++C+ + C+R +
Sbjct: 1651 ECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMR-----RSLCYRNYYADNQT 1705
Query: 351 CSLPILRNITKQICCCS-RVGKAWGRGCQLCPPFGSEGFREICPAG-PGYHYSASDLRYN 408
C +L N+TK++CCCS +G+AW + C+ CP ++ F +C + PG+ Y
Sbjct: 1706 CDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDI----YT 1761
Query: 409 TRPLGQEPPRVSLSQPRTLPATSRPSA--GFLPTHRLEPRPEPRPDPRPGPELPLPSIPA 466
P V + + R +P + + R E P +
Sbjct: 1762 GLP-------VDIDECREIPGVCENGVCINMVGSFRCEC---------PVGFFYNDKLLV 1805
Query: 467 WTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRR 526
+ ++GP +CQRN + CI+ Y C C G+R + G +C D +EC+
Sbjct: 1806 CEDIDECQNGP---VCQRNAE------CINTAGSYRCDCKPGYRFTSTG-QCNDRNECQE 1855
Query: 527 VPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFL 586
+P C+ G+C ++ GSF C+C GF+ CLD++EC R C G C NT GSF
Sbjct: 1856 IPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECER--DACGNGTCRNTIGSFN 1913
Query: 587 CVCPAGYQAAPHGASCQDVDECTQSPG-LCGRGACKNLPGSFRCVCPAGFR----GSACE 641
C C G+ + H C DVDEC G LC G C N GSF+C C G+ G C
Sbjct: 1914 CRCNHGFILS-HNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCV 1972
Query: 642 EDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRC 701
D++EC EP C PG C N GS+ C CP G+ + C+D+DEC P C G C
Sbjct: 1973 -DINECLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNE--KCEDIDECVEEPEICALGTC 2029
Query: 702 ENTEGSFQCVCPMGFQPNTAGSECEDV----------------DECENH----LAC---- 737
NTEGSF+C+CP GF +++G C+D+ + NH C
Sbjct: 2030 SNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKG 2089
Query: 738 -----PGQECVNSPGSFQCRTCPSGHHLHRG---RCTDVDECSSGAPPCGPHGHCTNTEG 789
P + C P + CP G + G D+DEC P HG C NT+G
Sbjct: 2090 EGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKE--PDVCKHGQCINTDG 2147
Query: 790 SFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGA 849
S+RC C GY C D +EC G+ C +G C N G F CTC G+ PGP
Sbjct: 2148 SYRCECPFGYILAGNE---CVDTDECSVGNPC-GNGTCKNVIGGFECTCEEGFEPGPM-M 2202
Query: 850 SCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQ 909
+C D++EC++ L + C NT GS+EC CP G+ D C D DEC E G C +
Sbjct: 2203 TCEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEE-GKHDCTEK 2261
Query: 910 R--CENSPGSYRCVRDCDPGYHAGPEGT-CDDVDECQEYGPEICGAQRCENTPGSYRCTP 966
+ C+N G+Y C+ C PGY P+G C D +ECQ P IC RC NT GSY C
Sbjct: 2262 QMECKNLIGTYMCI--CGPGYQRRPDGEGCVDENECQTK-PGICENGRCLNTRGSYTCE- 2317
Query: 967 ACDPGYQPTPGGGCQDVDECRN-----------RSFCGAHAVCQNLPGSFQCLCDQGYEG 1015
C+ G+ +P + DEC + ++ C + +N +C CD G
Sbjct: 2318 -CNDGFTASP-----NQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGW 2371
Query: 1016 ARDGRHC-------------------------VDVNECETLQGVCGAALCENVEGSFLCV 1050
G HC D++EC+ + VC C N GS+ C+
Sbjct: 2372 ---GPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRNGECVNDRGSYHCI 2428
Query: 1051 CPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVG 1110
C G P + +
Sbjct: 2429 CKT-----------------------GYTPDITGTSCVDLN------------------- 2446
Query: 1111 SGRRECYFDTAAPDACDNILARNVTWQECCCTVG---EGWGSGCR-IQQCPGTETAEYQS 1166
EC AP C+ I +C C G + G C+ + +C T+ Q
Sbjct: 2447 ----EC---NQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDEC-ATKQHNCQF 2498
Query: 1167 LCPHGRGYLA---PSGDLSLRR---DVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYY 1220
LC + G P G D +EC + G+C NT ++C C G+
Sbjct: 2499 LCVNTIGGFTCKCPPGFTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSL 2558
Query: 1221 HTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDN 1280
C D DEC + C+ G C N +G Y C+C + +CV +E++ L +
Sbjct: 2559 DQTGSSCEDVDEC-EGNHRCQHG-CQNIIGGYRCSCPQGYLQHYQWNQCV-DENECLSAH 2615
Query: 1281 L 1281
+
Sbjct: 2616 I 2616
Score = 450 bits (1157), Expect = e-126
Identities = 311/1009 (30%), Positives = 412/1009 (40%), Gaps = 181/1009 (17%)
Query: 482 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPG 541
C N +CG G+C++ P GY C CD GF S G C D+DEC +P C G C N PG
Sbjct: 1408 CSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECS-LPNICVFGTCHNLPG 1466
Query: 542 SFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGAS 601
FRC C G+ C DV+EC P C G C NTPGS++C CP ++ P
Sbjct: 1467 LFRCECEIGYELDRSGGNCTDVNECLD-PTTCISGNCVNTPGSYICDCPPDFELNPTRVG 1525
Query: 602 CQDVDE-----------------CTQSPGL--------CGRGACKNLP---------GSF 627
C D C+ G+ C G P +
Sbjct: 1526 CVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEY 1585
Query: 628 RCVCPAG--FRGSACE---EDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAP 682
+ +CP G FR + ED+DEC + P C G+C NT GSF C CP G+
Sbjct: 1586 KILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRV 1645
Query: 683 CQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDE--CENHLACPGQ 740
C DV+EC +P C G C NT G++ C+CP + G+ C D+ C + Q
Sbjct: 1646 CDDVNEC-ETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQ 1704
Query: 741 EC------------------VNSPGSFQCRTCPSGH-----------------HLHRGRC 765
C + + C CP ++ G
Sbjct: 1705 TCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLP 1764
Query: 766 TDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHG 825
D+DEC C +G C N GSFRC C G+ + + C D++EC G C +
Sbjct: 1765 VDIDECREIPGVC-ENGVCINMVGSFRCECPVGFFY-NDKLLVCEDIDECQNGPVCQRNA 1822
Query: 826 ECLNTDGSFACTCAPGYRPGPRGASCLDVDECSE-EDLCQSGICTNTDGSFECICPPGHR 884
EC+NT GS+ C C PGYR G C D +EC E ++C G C +T GSF C+C G +
Sbjct: 1823 ECINTAGSYRCDCKPGYRFTSTG-QCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFK 1881
Query: 885 AGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQE 944
D CLD++EC CG+ C N+ GS+ C C+ G+ C DVDEC
Sbjct: 1882 TNDDQTMCLDINECERDA---CGNGTCRNTIGSFNC--RCNHGFILSHNNDCIDVDECAS 1936
Query: 945 YGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGG-CQDVDECRNRSFCGAHAVCQNLPG 1003
+C +C NT GS++C C+ GY+ P G C D++EC A CQNL G
Sbjct: 1937 GNGNLCRNGQCINTVGSFQCQ--CNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDG 1994
Query: 1004 SFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTG 1063
S++C+C GY + C D++EC +C C N EGSF C+CP
Sbjct: 1995 SYRCICPPGY--SLQNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEG-FSLSSSGR 2051
Query: 1064 RCVPPRTSA--GTFPGSQPQAPASP---------VLPARPPPPPLPRRPSTPRQG----- 1107
RC R S F G + +P S L P P+ P +
Sbjct: 2052 RCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQIC 2111
Query: 1108 PVGSGRRECYFDTAA-------PDACDN------------------ILARN--VTWQECC 1140
P GSG D+A PD C + ILA N V EC
Sbjct: 2112 PYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYILAGNECVDTDECS 2171
Query: 1141 ------------------CTVGEGWGSG----CR-IQQCPGTET----------AEYQSL 1167
CT EG+ G C I +C Y+
Sbjct: 2172 VGNPCGNGTCKNVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYECK 2231
Query: 1168 CPHGRGYLAPSGDLSLRRDVDECQLFR-DQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLE 1226
CP G Y+ D + +D DEC+ + D K C N Y C C GY
Sbjct: 2232 CPVG--YVLRE-DRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEG 2288
Query: 1227 CIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQ 1286
C+D +EC + CE GRC+NT GSY C C +Q C LD+ G C+
Sbjct: 2289 CVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDEC-------LDNREGYCFT 2341
Query: 1287 EVGADLVCSHPRLDRQATYTECCCLYGEAWGMDCALCPAQDSDDFEALC 1335
EV ++ T +ECCC G WG C +CP Q + F+ LC
Sbjct: 2342 EVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLC 2390
Score = 439 bits (1130), Expect = e-123
Identities = 364/1251 (29%), Positives = 504/1251 (40%), Gaps = 282/1251 (22%)
Query: 220 GYCFRELRGGECASPLPGLR-TQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAP----- 273
G CF + C L G+ T+ +CC G AWG H C++C + R P
Sbjct: 184 GPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWG-HPCEMCPAQPHPCRRGFIPNIRTG 242
Query: 274 ---------------------------DGPCPTGFE--RVNGSCEDVDECAT-GGRCQHG 303
+ CP G + V+ CED+DEC+T G C+ G
Sbjct: 243 ACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGG 302
Query: 304 ECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQI 363
EC NT Y C CP GF + CI G C+ L +G CS + ++ITK
Sbjct: 303 ECTNTVSSYFCKCPPGFYTSPDGTRCIDVR-----PGYCYTALTNGRCSNQLPQSITKMQ 357
Query: 364 CCCSRVGKAWGRGC----QLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRV 419
CCC G+ W G ++CP +E F ++C
Sbjct: 358 CCCD-AGRCWSPGVTVAPEMCPIRATEDFNKLC--------------------------- 389
Query: 420 SLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDP---RPGPELPLPSIPA---WTGPEIP 473
S P +P RP P L P P P P PGP++P+P P + E P
Sbjct: 390 --SVPMVIP--GRPE---YPPPPLGPIPPVLPVPPGFPPGPQIPVPRPPVEYLYPSREPP 442
Query: 474 ESGP--SSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPC 531
P + CQ +C GRCI P C C+ GF+L +G CIDVDEC + PC
Sbjct: 443 RVLPVNVTDYCQLVRYLCQNGRCIPTPGSCRCECNKGFQLDLRG-ECIDVDECEK--NPC 499
Query: 532 APGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPA 591
A G C N+ GS+ C C G+++ EC D+DEC + C+ GRC NT GSF CVC A
Sbjct: 500 AGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNA 559
Query: 592 GYQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFR----GSACEEDVDEC 647
G+ G +C+D+DEC+ +C G C N GSF+C+C GF+ G C +D++EC
Sbjct: 560 GFHVTRDGKNCEDMDECS-IRNMCLNGMCINEDGSFKCICKPGFQLASDGRYC-KDINEC 617
Query: 648 AQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDV--------------------- 686
+ P C GRC NT GS+ C C G G C D
Sbjct: 618 -ETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFG 676
Query: 687 ----DECARSPPPCTYGR-CE----NTEGSFQCVCPMGFQPNTAGSECEDVDECE-NHLA 736
EC + +G C+ +Q +C G +AGS D++EC +
Sbjct: 677 AVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGS---DINECALDPDI 733
Query: 737 CPGQECVNSPGSFQCRTCPSGHHLHR--GRCTDVDECSSGAPPCGPHGHCTNTEGSFRCS 794
CP C N G+++C C SG+ + C D++EC + C +G C NT GSF C+
Sbjct: 734 CPNGICENLRGTYKC-ICNSGYEVDSTGKNCVDINECVLNSLLC-DNGQCRNTPGSFVCT 791
Query: 795 CAPGY-RAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLD 853
C G+ P + C D++EC E C +G C N+ GSF C C+ P C++
Sbjct: 792 CPKGFIYKPDLK--TCEDIDEC-ESSPCI-NGVCKNSPGSFICECSSESTLDPTKTICIE 847
Query: 854 VDE---------------------------------------CSEEDLCQSG-------- 866
+ C + +C G
Sbjct: 848 TIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQ 907
Query: 867 ------------IC-----TNTDGSFECICPPGHRAGPDLASCLDV-----------DEC 898
+C NT GSF+C CP G CLD+ +EC
Sbjct: 908 CEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEEC 967
Query: 899 ------RERGPALC-------GSQRCENSP----GSYRCVRDCDPGYHAGPEGT-----C 936
R R A C G++ CE P Y + PG+ A E T
Sbjct: 968 TLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGF-ATKEITNGKPFF 1026
Query: 937 DDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQ-PTPGGGCQDVDECR-NRSFCGA 994
D++EC+ P +C +C NT GS++C CD G+ + C D+DECR + CG
Sbjct: 1027 KDINECKMI-PSLCTHGKCRNTIGSFKC--RCDSGFALDSEERNCTDIDECRISPDLCG- 1082
Query: 995 HAVCQNLPGSFQCLCDQGYE-GARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPN 1053
C N PG F+C CD+GYE G ++C+D++EC+ +C +C N EGS+ C CP
Sbjct: 1083 RGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPP 1142
Query: 1054 SPEEFDPMTGRCV---PPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVG 1110
+ P C+ SA P + L + P STP +
Sbjct: 1143 G-HQLSPNISACIDINECELSAHLCPNGR-----CVNLIGKYQCACNPGYHSTPDR-LFC 1195
Query: 1111 SGRRECYFDTAAPDACDNILARNVTWQECCCTVG----------------EGWGSGCRIQ 1154
EC + C+ + EC C G E + C
Sbjct: 1196 VDIDEC---SIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGG 1252
Query: 1155 QCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYC 1214
QC EY+ LC G S D+ DV+EC L +C SG C NT + C+C
Sbjct: 1253 QCTNI-PGEYRCLCYDG---FMASEDMKTCVDVNECDL-NPNICLSGTCENTKGSFICHC 1307
Query: 1215 SNGYYYHTQRLECIDNDECADEEPAC-EGGRCVNTVGSYHCTCEPPLVLDG 1264
GY + C D +EC C + C NT GS+ C+C P + DG
Sbjct: 1308 DMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDG 1358
Score = 437 bits (1123), Expect = e-122
Identities = 288/855 (33%), Positives = 377/855 (44%), Gaps = 155/855 (18%)
Query: 519 IDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRC 578
+D+DECR +P C G C N GSFRC C GF + C D+DEC P C
Sbjct: 1765 VDIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAEC 1824
Query: 579 ENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGS 638
NT GS+ C C GY+ G C D +EC + P +C G C + GSF C+C GF+ +
Sbjct: 1825 INTAGSYRCDCKPGYRFTSTG-QCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTN 1883
Query: 639 ACEE---DVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPP 695
+ D++EC ++ CG G C NT GSF+C C GF C DVDECA
Sbjct: 1884 DDQTMCLDINECERDA--CGNGTCRNTIGSFNCRCNHGF-ILSHNNDCIDVDECASGNGN 1940
Query: 696 -CTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDEC--ENHLACPGQECVNSPGSFQCR 752
C G+C NT GSFQC C G++ G C D++EC E PG C N GS++C
Sbjct: 1941 LCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGT-CQNLDGSYRC- 1998
Query: 753 TCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYR-APSGRP----- 806
CP G+ L +C D+DEC C G C+NTEGSF+C C G+ + SGR
Sbjct: 1999 ICPPGYSLQNEKCEDIDECVEEPEICAL-GTCSNTEGSFKCLCPEGFSLSSSGRRCQDLR 2057
Query: 807 ----------GPCADVN-------EC---LEGDFCFPHGECLNTDGSFA----CTCAPGY 842
G C+ EC L+G+ E T+ A C G
Sbjct: 2058 MSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGI 2117
Query: 843 RPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERG 902
GP S +D+DEC E D+C+ G C NTDGS+ C CP G+ + C+D DEC
Sbjct: 2118 IVGPDD-SAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYILAGN--ECVDTDECSVGN 2174
Query: 903 PALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSY 962
P CG+ C+N G + C C+ G+ GP TC+D++EC + P +C A RC NT GSY
Sbjct: 2175 P--CGNGTCKNVIGGFECT--CEEGFEPGPMMTCEDINECAQ-NPLLC-AFRCVNTYGSY 2228
Query: 963 RCTPACDPGYQPTPGGG-CQDVDECRN-RSFCGAHAV-CQNLPGSFQCLCDQGYEGARDG 1019
C C GY C+D DEC + C + C+NL G++ C+C GY+ DG
Sbjct: 2229 ECK--CPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDG 2286
Query: 1020 RHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQ 1079
CVD NEC+T G+C C N GS+ C C N P C+ R Q
Sbjct: 2287 EGCVDENECQTKPGICENGRCLNTRGSYTCEC-NDGFTASPNQDECLDNREGYCFTEVLQ 2345
Query: 1080 PQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQEC 1139
+GS R VT EC
Sbjct: 2346 NMCQ-------------------------IGSSNRN-----------------PVTKSEC 2363
Query: 1140 CCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQ--- 1196
CC G GWG C I CP T ++ LCPHGRG++ D +DEC++ D
Sbjct: 2364 CCDGGRGWGPHCEI--CPFQGTVAFKKLCPHGRGFMTNGAD------IDECKVIHDVCRN 2415
Query: 1197 ------------VCKSG-------------------------VCVNTAPGYSCYCSNGYY 1219
+CK+G +C NT Y C C GY
Sbjct: 2416 GECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYI 2475
Query: 1220 YHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDD 1279
C D DECA ++ C+ CVNT+G + C C P + C+ N + D
Sbjct: 2476 LQEDGRSCKDLDECATKQHNCQ-FLCVNTIGGFTCKCPPGFTQHHTS--CIDNNECTSDI 2532
Query: 1280 NL----GVCWQEVGA 1290
NL G+C G+
Sbjct: 2533 NLCGSKGICQNTPGS 2547
Score = 386 bits (992), Expect = e-107
Identities = 255/763 (33%), Positives = 337/763 (44%), Gaps = 72/763 (9%)
Query: 227 RGGECASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAP------DGP---- 276
R G+C + + + Q C G +A C +E L R AP DG
Sbjct: 1943 RNGQCINTVGSFQCQ--CNEGYEVAPDGRTCVDINECL-LEPRKCAPGTCQNLDGSYRCI 1999
Query: 277 CPTGFERVNGSCEDVDECATGGR-CQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVI 335
CP G+ N CED+DEC C G C+NT G + C+CP+GF L SS C +
Sbjct: 2000 CPPGYSLQNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRM- 2058
Query: 336 SEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREICPAG 395
C+ G CS P RN +KQ CCC+ G+ WG C+LCP E FR+ICP G
Sbjct: 2059 ----SYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYG 2114
Query: 396 PGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSR---PSAGFLPTHRLEPRPEPRPD 452
G D + +EP Q + R P L + E
Sbjct: 2115 SGIIVGPDDSAVDMDEC-KEPDVCKHGQCINTDGSYRCECPFGYILAGNECVDTDECSVG 2173
Query: 453 PRPGPELPLPSIPAW--TGPEIPESGPSS-----GMCQRNPQVCGPGRCISRPSGYTCAC 505
G I + T E E GP C +NP +C RC++ Y C C
Sbjct: 2174 NPCGNGTCKNVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCA-FRCVNTYGSYECKC 2232
Query: 506 DSGFRLSPQGTRCIDVDECRRVPPPCAPGR--CENSPGSFRCVCGPGFRAGPRAAECLDV 563
G+ L C D DEC C + C+N G++ C+CGPG++ P C+D
Sbjct: 2233 PVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDE 2292
Query: 564 DECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDE---------------- 607
+EC P C+ GRC NT GS+ C C G+ A+P+ C D E
Sbjct: 2293 NECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGS 2352
Query: 608 -----CTQSPGLC--GRG---ACKNLPG----SFRCVCPAGFRGSACEEDVDECAQEPPP 653
T+S C GRG C+ P +F+ +CP G D+DEC
Sbjct: 2353 SNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKVIHDV 2412
Query: 654 CGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCP 713
C G C N GS+HC C G+ G C D++EC ++P PC + C+NTEGS+QC CP
Sbjct: 2413 CRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCNF-ICKNTEGSYQCSCP 2471
Query: 714 MGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSS 773
G+ G C+D+DEC CVN+ G F C+ CP G H C D +EC+S
Sbjct: 2472 KGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGGFTCK-CPPGFTQHHTSCIDNNECTS 2530
Query: 774 GAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGS 833
CG G C NT GSF C C G+ C DV+EC EG+ HG C N G
Sbjct: 2531 DINLCGSKGICQNTPGSFTCECQRGFSLDQ-TGSSCEDVDEC-EGNHRCQHG-CQNIIGG 2587
Query: 834 FACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCL 893
+ C+C GY + C+D +EC +C C NT GS++C+CP G + C
Sbjct: 2588 YRCSCPQGYLQHYQWNQCVDENECLSAHICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQ 2647
Query: 894 DVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTC 936
D++EC A C S C N+ G Y C C PGY +G C
Sbjct: 2648 DINECGS-AQAPC-SYGCSNTEGGYLC--GCPPGYFRIGQGHC 2686
Score = 381 bits (978), Expect = e-105
Identities = 274/864 (31%), Positives = 362/864 (41%), Gaps = 144/864 (16%)
Query: 482 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPP-CAPGRCENSP 540
C+R+ CG G C + + C C+ GF LS CIDVDEC C G+C N+
Sbjct: 1895 CERD--ACGNGTCRNTIGSFNCRCNHGFILS-HNNDCIDVDECASGNGNLCRNGQCINTV 1951
Query: 541 GSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGA 600
GSF+C C G+ P C+D++EC P C G C+N GS+ C+CP GY
Sbjct: 1952 GSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSL--QNE 2009
Query: 601 SCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFR----GSACEE-DVDECAQEPPPCG 655
C+D+DEC + P +C G C N GSF+C+CP GF G C++ + C +
Sbjct: 2010 KCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAK---FE 2066
Query: 656 PGRCDNTAGSFHCA--CPAGFRSRGPGAPCQ----------------------------- 684
G+C + H C + G G PC+
Sbjct: 2067 GGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAV 2126
Query: 685 DVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVN 744
D+DEC + P C +G+C NT+GS++C CP G+ AG+EC D DEC C C N
Sbjct: 2127 DMDEC-KEPDVCKHGQCINTDGSYRCECPFGYI--LAGNECVDTDECSVGNPCGNGTCKN 2183
Query: 745 SPGSFQCRTCPSGHHLH-RGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPS 803
G F+C TC G C D++EC+ C C NT GS+ C C GY
Sbjct: 2184 VIGGFEC-TCEEGFEPGPMMTCEDINECAQNPLLCA--FRCVNTYGSYECKCPVGYVLRE 2240
Query: 804 GRPGPCADVNECLEG--DFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDEC-SEE 860
R C D +EC EG D EC N G++ C C PGY+ P G C+D +EC ++
Sbjct: 2241 DRR-MCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKP 2299
Query: 861 DLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDE-----------CR----ERGPAL 905
+C++G C NT GS+ C C G A P+ CLD E C+ R P
Sbjct: 2300 GICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVT 2359
Query: 906 -----CGSQR-----CENSP--GSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQ 953
C R CE P G+ + C G G D+DEC+ ++C
Sbjct: 2360 KSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGA--DIDECKVIH-DVCRNG 2416
Query: 954 RCENTPGSYRCTPACDPGYQPT-PGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQG 1012
C N GSY C C GY P G C D++EC N++ + +C+N GS+QC C +G
Sbjct: 2417 ECVNDRGSYHCI--CKTGYTPDITGTSCVDLNEC-NQAPKPCNFICKNTEGSYQCSCPKG 2473
Query: 1013 YEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPR--T 1070
Y DGR C D++EC T Q C LC N G F C C P F C+ T
Sbjct: 2474 YILQEDGRSCKDLDECATKQHNC-QFLCVNTIGGFTCKC---PPGFTQHHTSCIDNNECT 2529
Query: 1071 SAGTFPGSQ---PQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACD 1127
S GS+ P S + R S + G EC + C
Sbjct: 2530 SDINLCGSKGICQNTPGSFTCECQ-------RGFSLDQTGSSCEDVDECEGNHRCQHGCQ 2582
Query: 1128 NILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDV 1187
NI+ Y+ CP +GYL + V
Sbjct: 2583 NIIGG-------------------------------YRCSCP--QGYLQ---HYQWNQCV 2606
Query: 1188 DECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVN 1247
DE + +C C NT Y C C G+ Y C D +EC + C G C N
Sbjct: 2607 DENECLSAHICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPCSYG-CSN 2665
Query: 1248 TVGSYHCTCEPPLVLDGSQRRCVS 1271
T G Y C C PP Q CVS
Sbjct: 2666 TEGGYLCGC-PPGYFRIGQGHCVS 2688
Score = 368 bits (944), Expect = e-101
Identities = 288/970 (29%), Positives = 394/970 (40%), Gaps = 234/970 (24%)
Query: 467 WTGPEIPE---SGP-----SSGMCQRNPQ--VCGPGRC---ISRPSGYTCA--------C 505
+TGP+ +GP S+ MCQ VC C + R G+ C C
Sbjct: 172 FTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQPHPC 231
Query: 506 DSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDE 565
GF + + C DVDEC+ +P C G C N+ GSF C C G + + +C D+DE
Sbjct: 232 RRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDE 291
Query: 566 CHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLC----GRGACK 621
C +P C+ G C NT S+ C CP G+ +P G C DV PG C G C
Sbjct: 292 CSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDV-----RPGYCYTALTNGRCS 346
Query: 622 N-LPGS---FRCVCPAGFRGS-------------ACEEDVDECA----------QEPPPC 654
N LP S +C C AG S A E+ C+ PPP
Sbjct: 347 NQLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNKLCSVPMVIPGRPEYPPPPL 406
Query: 655 GPGRCDNTAGSFHCACPAG-------------FRSRGPG--APCQDVDECARSPPPCTYG 699
GP P G + SR P P D C C G
Sbjct: 407 GP---IPPVLPVPPGFPPGPQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQLVRYLCQNG 463
Query: 700 RCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHH 759
RC T GS +C C GFQ + G EC DVDECE + C G EC+N+ GS+ C+ C +G+
Sbjct: 464 RCIPTPGSCRCECNKGFQLDLRG-ECIDVDECEKN-PCAGGECINNQGSYTCQ-CRAGYQ 520
Query: 760 --LHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGP-CADVNECL 816
L R C D+DEC C +G C NT+GSF C C G+ R G C D++EC
Sbjct: 521 STLTRTECRDIDECLQNGRICN-NGRCINTDGSFHCVCNAGFHVT--RDGKNCEDMDECS 577
Query: 817 EGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFE 876
+ C +G C+N DGSF C C PG++ G C D++EC +C +G C NTDGS+
Sbjct: 578 IRNMCL-NGMCINEDGSFKCICKPGFQLASDGRYCKDINECETPGICMNGRCVNTDGSYR 636
Query: 877 CICPPGHRAGPDLASCLDV-------------------------DECRERGPALCGSQRC 911
C C PG G D C+D EC + C
Sbjct: 637 CECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPC 696
Query: 912 ENSP----GSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPA 967
+ P Y+ + PG + D++EC P+IC CEN G+Y+C
Sbjct: 697 QPCPAQNSAEYQALCSSGPGMTSAG----SDINEC-ALDPDICPNGICENLRGTYKC--I 749
Query: 968 CDPGYQ-PTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVN 1026
C+ GY+ + G C D++EC S + C+N PGSF C C +G+ D + C D++
Sbjct: 750 CNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDID 809
Query: 1027 ECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASP 1086
ECE+ C +C+N GSF+C C +S DP C+ T GT
Sbjct: 810 ECES--SPCINGVCKNSPGSFICEC-SSESTLDPTKTICI--ETIKGT------------ 852
Query: 1087 VLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEG 1146
C+ T C+ + +CC ++G
Sbjct: 853 -----------------------------CW-QTVIDGRCEININGATLKSQCCSSLGAA 882
Query: 1147 WGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNT 1206
WGS C + + +C G+GY G + D+DEC++F VCK+G+CVNT
Sbjct: 883 WGSPCTL--------CQVDPIC--GKGYSRIKG--TQCEDIDECEVF-PGVCKNGLCVNT 929
Query: 1207 APGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQ 1266
+ C C +G + LD +
Sbjct: 930 RGSFKCQCPSG------------------------------------------MTLDATG 947
Query: 1267 RRCVSNESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLYGEAWGM-DCALCPA 1325
R C LD L C+ D C+ P R CCC G AWG +C CP
Sbjct: 948 RIC-------LDIRLETCFLRY-EDEECTLPIAGRH-RMDACCCSVGAAWGTEECEECPM 998
Query: 1326 QDSDDFEALC 1335
+++ ++E LC
Sbjct: 999 RNTPEYEELC 1008
Score = 359 bits (922), Expect = 1e-98
Identities = 370/1313 (28%), Positives = 500/1313 (38%), Gaps = 254/1313 (19%)
Query: 198 APYTVLAQSAPREDGYSDASGFGYCFRELRGGECASPLP---GLRTQEVCCRGAGLAWGV 254
A YT A E G + R GG A P G R CC G G
Sbjct: 18 ASYTSHGADANLEAGNVKETRASRAKRRGGGGHDALKGPNVCGSRYNAYCCPGWKTLPGG 77
Query: 255 HDC--QLCSERLGNSERVSAPDGPCPTGFERVNGSCEDVD------ECATGGRCQHGECA 306
+ C +C G+ CP+G ++ SC C GG C C
Sbjct: 78 NQCIVPICRHSCGDGFCSRPNMCTCPSG--QIAPSCGSRSIQHCNIRCMNGGSCSDDHCL 135
Query: 307 NTRG--GYTC---VCPDGFL-----LDSSRSSCISQHVISEAK-----GPCFRVLRDGGC 351
+G G C VC G L + +R +C + + GPCF V+ + C
Sbjct: 136 CQKGYIGTHCGQPVCESGCLNGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVISNQMC 195
Query: 352 SLPILRNITKQICCCSRVGKAWGRGCQLCPP--------------FGSEGFREICPAGPG 397
+ + + CC+ VG+AWG C++CP G+ + C A PG
Sbjct: 196 QGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPG 255
Query: 398 YHYSASDLRYNT-------RPLGQEPPRVS-----LSQPRTLP-------ATSRPSAGFL 438
+ + NT P G + VS + + T+P T+ S+ F
Sbjct: 256 LCQGGNCI--NTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFC 313
Query: 439 ---PTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCI 495
P P D RPG ++P+S C C GRC
Sbjct: 314 KCPPGFYTSPDGTRCIDVRPG-YCYTALTNGRCSNQLPQSITKMQCC------CDAGRCW 366
Query: 496 SRPSGYTCACDSGFRLSPQGTRCIDVDECRRV--PPPCAPGRCENSPGSFRCV-----CG 548
S G ++P+ ++ ++ P PGR E P +
Sbjct: 367 S----------PGVTVAPEMCPIRATEDFNKLCSVPMVIPGRPEYPPPPLGPIPPVLPVP 416
Query: 549 PGFRAGPRAAECLDVDEC---HRVPPP---------CDLGR--CEN-----TPGSFLCVC 589
PGF GP+ E R PP C L R C+N TPGS C C
Sbjct: 417 PGFPPGPQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQLVRYLCQNGRCIPTPGSCRCEC 476
Query: 590 PAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACE---EDVDE 646
G+Q G C DVDEC ++P C G C N GS+ C C AG++ + D+DE
Sbjct: 477 NKGFQLDLRG-ECIDVDECEKNP--CAGGECINNQGSYTCQCRAGYQSTLTRTECRDIDE 533
Query: 647 CAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEG 706
C Q C GRC NT GSFHC C AGF G C+D+DEC+ C G C N +G
Sbjct: 534 CLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECS-IRNMCLNGMCINEDG 592
Query: 707 SFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQC------------RTC 754
SF+C+C GFQ + G C+D++ECE C CVN+ GS++C R C
Sbjct: 593 SFKCICKPGFQLASDGRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVC 652
Query: 755 PSGH-------HLHRGRC-------TDVDECSSGA------PPCGPHGHCTNTEGSFRCS 794
H RG+C EC + PC P + E CS
Sbjct: 653 VDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCS 712
Query: 795 CAPGYRAPSGRPGPCADVNEC-LEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLD 853
PG + +D+NEC L+ D C P+G C N G++ C C GY G +C+D
Sbjct: 713 SGPGMTSAG------SDINECALDPDIC-PNGICENLRGTYKCICNSGYEVDSTGKNCVD 765
Query: 854 VDECSEED-LCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCE 912
++EC LC +G C NT GSF C CP G PDL +C D+DEC E P + G C+
Sbjct: 766 INECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDEC-ESSPCINGV--CK 822
Query: 913 NSPGSYRCVRDCDPGYHAGP---------EGTC-----DDVDECQEYGPEICGAQRCENT 958
NSPGS+ C +C P +GTC D E G + +Q C +
Sbjct: 823 NSPGSFIC--ECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATL-KSQCCSSL 879
Query: 959 PGSY--RCT-----PACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQ 1011
++ CT P C GY G C+D+DEC + +C N GSF+C C
Sbjct: 880 GAAWGSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPS 939
Query: 1012 GYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFD-PMTGR------ 1064
G GR C+D+ ET C EE P+ GR
Sbjct: 940 GMTLDATGRICLDI-RLET------------------CFLRYEDEECTLPIAGRHRMDAC 980
Query: 1065 CVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPD 1124
C + GT + +P P P P EC P
Sbjct: 981 CCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINEC---KMIPS 1037
Query: 1125 ACDNILARNVTWQ-ECCCTVGEGWGS---------GCRIQ-------QCPGTETAEYQSL 1167
C + RN +C C G S CRI QC T +++
Sbjct: 1038 LCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNT-PGDFECK 1096
Query: 1168 CPHGRGYLAPSGDLSLRR--DVDECQLFRDQ-VCKSGVCVNTAPGYSCYCSNGYYYHTQR 1224
C G SG + ++ D+DECQ RD +C+ GVC NT Y C C G+
Sbjct: 1097 CDEG----YESGFMMMKNCMDIDECQ--RDPLLCRGGVCHNTEGSYRCECPPGHQLSPNI 1150
Query: 1225 LECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVC 1284
CID +EC C GRCVN +G Y C C P + CV + S+ +
Sbjct: 1151 SACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNG---- 1206
Query: 1285 WQEVGADLVCSHPRLDRQATYTECCCLYGEAWGMDCALCPAQDS-DDFEALCN 1336
G + C+ + + +Y EC C G A D C D +D +C+
Sbjct: 1207 ----GCETFCT----NSEGSY-ECSCQPGFALMPDQRSCTDIDECEDNPNICD 1250
Score = 202 bits (514), Expect = 2e-51
Identities = 111/307 (36%), Positives = 148/307 (48%), Gaps = 13/307 (4%)
Query: 475 SGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPG 534
+G C+ VC G C++ Y C C +G+ GT C+D++EC + P PC
Sbjct: 2399 NGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCN-F 2457
Query: 535 RCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQ 594
C+N+ GS++C C G+ C D+DEC C C NT G F C CP G+
Sbjct: 2458 ICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQF-LCVNTIGGFTCKCPPGF- 2515
Query: 595 AAPHGASCQDVDECTQSPGLCG-RGACKNLPGSFRCVCPAGFR----GSACEEDVDECAQ 649
H SC D +ECT LCG +G C+N PGSF C C GF GS+CE DVDEC +
Sbjct: 2516 -TQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQTGSSCE-DVDEC-E 2572
Query: 650 EPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQ 709
C G C N G + C+CP G+ C D +EC S C C NT GS++
Sbjct: 2573 GNHRCQHG-CQNIIGGYRCSCPQGYLQHYQWNQCVDENECL-SAHICGGASCHNTLGSYK 2630
Query: 710 CVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVD 769
C+CP GFQ C+D++EC + A C N+ G + C P + +G C
Sbjct: 2631 CMCPAGFQYEQFSGGCQDINECGSAQAPCSYGCSNTEGGYLCGCPPGYFRIGQGHCVSGM 2690
Query: 770 ECSSGAP 776
G P
Sbjct: 2691 GMGRGNP 2697
Score = 197 bits (502), Expect = 5e-50
Identities = 179/627 (28%), Positives = 244/627 (38%), Gaps = 133/627 (21%)
Query: 946 GPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNR---SFCGAHAVCQNLP 1002
GP +CG+ R C PG++ PGG V CR+ FC +C
Sbjct: 55 GPNVCGS----------RYNAYCCPGWKTLPGGNQCIVPICRHSCGDGFCSRPNMCTCPS 104
Query: 1003 GSFQCLCDQGYEGARDGRHC---------VDVNECETLQGV----CGAALCENVEGSFLC 1049
G C G+R +HC + C +G CG +CE+
Sbjct: 105 GQIAPSC-----GSRSIQHCNIRCMNGGSCSDDHCLCQKGYIGTHCGQPVCESG------ 153
Query: 1050 VCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPV 1109
C N GRCV P A T+ + PQ R GP
Sbjct: 154 -CLNG--------GRCVAPNRCACTYGFTGPQCERDY------------------RTGPC 186
Query: 1110 GSGRRECYFDTAAPDACDNILARNV-TWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLC 1168
F + C L+ V T CC TVG WG C + CP
Sbjct: 187 --------FTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHPC--EMCPAQPH------- 229
Query: 1169 PHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECI 1228
P RG++ P+ +DVDECQ +C+ G C+NT + C C G+ + +C
Sbjct: 230 PCRRGFI-PNIRTGACQDVDECQAIPG-LCQGGNCINTVGSFECKCPAGHKLNEVSQKCE 287
Query: 1229 DNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEV 1288
D DEC+ CEGG C NTV SY C C P RC+ D G C+ +
Sbjct: 288 DIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCI-------DVRPGYCYTAL 340
Query: 1289 GADLVCSHPRLDRQATYTECCCLYGEAW--GMDCA--LCPAQDSDDFEALCNVLRPPAYS 1344
+ CS+ +L + T +CCC G W G+ A +CP + ++DF LC+V P
Sbjct: 341 -TNGRCSN-QLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNKLCSV---PMVI 395
Query: 1345 PPRPGGFGLPYEYGPD-LGPPYQGLPYGPELYPPPALPYDPYPPPPGPFARREAPYGAPR 1403
P RP EY P LGP LP P P P +P P PP + RE P P
Sbjct: 396 PGRP-------EYPPPPLGPIPPVLPVPPGFPPGPQIPV-PRPPVEYLYPSREPPRVLP- 446
Query: 1404 FDMPDFEDDGGPYGESEAPAPPGPGTRWPYRSRDTRRSFPEPEEPPEGGSYAGSLAEPYE 1463
++ D+ + R P P + L E
Sbjct: 447 VNVTDY-------------------CQLVRYLCQNGRCIPTPGSCRCECNKGFQLDLRGE 487
Query: 1464 ELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 1523
++ +EC + C G C+ +TC+C GY+ +TR C DI+EC + +C N
Sbjct: 488 CIDVDECE-KNPCAGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQN---GRICNN 543
Query: 1524 ARCLNTDGSFRCICRPGFAPTHQPHHC 1550
RC+NTDGSF C+C GF T +C
Sbjct: 544 GRCINTDGSFHCVCNAGFHVTRDGKNC 570
Score = 180 bits (456), Expect = 1e-44
Identities = 237/894 (26%), Positives = 310/894 (34%), Gaps = 191/894 (21%)
Query: 718 PNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCT--DVDECSSG- 774
PN GS N CPG + + PG QC H G C+ ++ C SG
Sbjct: 56 PNVCGSRY-------NAYCCPGWKTL--PGGNQCIVPICRHSCGDGFCSRPNMCTCPSGQ 106
Query: 775 -APPCGPHG--HCT------NTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHG 825
AP CG HC + C C GY C + CL G C
Sbjct: 107 IAPSCGSRSIQHCNIRCMNGGSCSDDHCLCQKGYIGTHCGQPVCE--SGCLNGGRCVAPN 164
Query: 826 ECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQ---SGI-CTNTDGSFECICPP 881
C T G C YR GP C V +CQ SGI CT T +C
Sbjct: 165 RCACTYGFTGPQCERDYRTGP----CFTV---ISNQMCQGQLSGIVCTKT------LC-- 209
Query: 882 GHRAGPDLASCLDVDECRERGPALCGSQRCENSPGS-YRCVRDCDPGYHAGPEGTCDDVD 940
C G A CE P + C R P G C DVD
Sbjct: 210 ----------------CATVGRAW--GHPCEMCPAQPHPCRRGFIPNIRTG---ACQDVD 248
Query: 941 ECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTP-GGGCQDVDECRNRSFCGAHAVCQ 999
ECQ P +C C NT GS+ C C G++ C+D+DEC C
Sbjct: 249 ECQAI-PGLCQGGNCINTVGSFECK--CPAGHKLNEVSQKCEDIDECSTIPGICEGGECT 305
Query: 1000 NLPGSFQCLCDQGYEGARDGRHCVDVNE--CETL--QGVCGAALCENVEGSFLC------ 1049
N S+ C C G+ + DG C+DV C T G C L +++ C
Sbjct: 306 NTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQLPQSITKMQCCCDAGRC 365
Query: 1050 ----------VCP-NSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLP 1098
+CP + E+F+ + C P G P P P+ P P PP P
Sbjct: 366 WSPGVTVAPEMCPIRATEDFNKL---CSVPMVIPGR--PEYPPPPLGPIPPVLPVPPGFP 420
Query: 1099 RRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPG 1158
P P P E + + P +L NVT + C V +G R PG
Sbjct: 421 PGPQIPVPRPPV----EYLYPSREPP---RVLPVNVT--DYCQLVRYLCQNG-RCIPTPG 470
Query: 1159 TETAEYQSLCPHGRGYLAPSGDLSLRR---DVDECQLFRDQVCKSGVCVNTAPGYSCYCS 1215
+ C +G+ L LR DVDEC+ C G C+N Y+C C
Sbjct: 471 S------CRCECNKGF-----QLDLRGECIDVDECE---KNPCAGGECINNQGSYTCQCR 516
Query: 1216 NGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQ 1275
GY R EC D DEC C GRC+NT GS+HC C + + C +
Sbjct: 517 AGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDEC 576
Query: 1276 SLDDNL--GVCWQEVGADLVCSHP--RLDRQATY----TEC----CCLYGEAWGMD---- 1319
S+ + G+C E G+ P +L Y EC C+ G D
Sbjct: 577 SIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECETPGICMNGRCVNTDGSYR 636
Query: 1320 CALCP--AQDSDDFEALCNVLRPPAYSPPRPGGFGLPYEYGPDLGPPYQGLPYGPELYPP 1377
C P A D + +R Y GG Y+ G + P + +
Sbjct: 637 CECFPGLAVGLDGRVCVDTHMRSTCY-----GG----YKRGQCIKPLFGAVTKSECC--- 684
Query: 1378 PALPYDPYPPPPGPFARREAPYGAPRFDMPDFEDDGGPYGESEAPAPPGPGTRWPYRSRD 1437
A E +G P P E +A GPG D
Sbjct: 685 --------------CASTEYAFGEPCQPCPAQNS-----AEYQALCSSGPG--MTSAGSD 723
Query: 1438 TRRSFPEPEEPPEG------GSYAGSLAEPYE-ELEAEECGILDGCT-------NGRCVR 1483
+P+ P G G+Y YE + + C ++ C NG+C
Sbjct: 724 INECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRN 783
Query: 1484 VPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCIC 1537
P F C C G+ C DI+EC+ +SP C+N C N+ GSF C C
Sbjct: 784 TPGSFVCTCPKGFIYKPDLKTCEDIDECE----SSP-CINGVCKNSPGSFICEC 832
Score = 142 bits (357), Expect = 3e-33
Identities = 82/229 (35%), Positives = 111/229 (48%), Gaps = 22/229 (9%)
Query: 494 CISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPC-APGRCENSPGSFRCVCGPGFR 552
C++ G+TC C GF + T CID +EC C + G C+N+PGSF C C GF
Sbjct: 2500 CVNTIGGFTCKCPPGF--TQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFS 2557
Query: 553 AGPRAAECLDVDEC---HRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECT 609
+ C DVDEC HR C G C+N G + C CP GY C D +EC
Sbjct: 2558 LDQTGSSCEDVDECEGNHR----CQHG-CQNIIGGYRCSCPQGYLQHYQWNQCVDENECL 2612
Query: 610 QSPGLCGRGACKNLPGSFRCVCPAGFR----GSACEEDVDECAQEPPPCGPGRCDNTAGS 665
S +CG +C N GS++C+CPAGF+ C+ D++EC PC G C NT G
Sbjct: 2613 -SAHICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQ-DINECGSAQAPCSYG-CSNTEGG 2669
Query: 666 FHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENT----EGSFQC 710
+ C CP G+ G G + +P P G ++ E ++C
Sbjct: 2670 YLCGCPPGYFRIGQGHCVSGMGMGRGNPEPPVSGEMDDNSLSPEACYEC 2718
Score = 74.7 bits (182), Expect = 6e-13
Identities = 33/77 (42%), Positives = 44/77 (57%), Gaps = 4/77 (5%)
Query: 1466 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNAR 1525
+ +EC I + C NG C+ F C C G++L C DINEC+ +C+N R
Sbjct: 572 DMDECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECE----TPGICMNGR 627
Query: 1526 CLNTDGSFRCICRPGFA 1542
C+NTDGS+RC C PG A
Sbjct: 628 CVNTDGSYRCECFPGLA 644
Score = 72.0 bits (175), Expect = 4e-12
Identities = 58/206 (28%), Positives = 92/206 (44%), Gaps = 17/206 (8%)
Query: 206 SAPREDGYSDASGFGYCFRELRGGEC--ASPLPGLRTQEVCCRGAGLAWGVHDCQLCSER 263
++P +D D + GYCF E+ C S T+ CC G WG H C++C +
Sbjct: 2324 ASPNQDECLD-NREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPH-CEICPFQ 2381
Query: 264 LGNSERVSAPDGPCPTGFERVNGSCEDVDECAT-GGRCQHGECANTRGGYTCVCPDGFLL 322
+ + P G GF NG+ D+DEC C++GEC N RG Y C+C G+
Sbjct: 2382 GTVAFKKLCPHG---RGF-MTNGA--DIDECKVIHDVCRNGECVNDRGSYHCICKTGYTP 2435
Query: 323 DSSRSSCISQHVISEAKGPCFRVLRDG----GCSLPILRNITKQICCCSRVGKAWGR--G 376
D + +SC+ + ++A PC + ++ CS P + + C + + +
Sbjct: 2436 DITGTSCVDLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHN 2495
Query: 377 CQLCPPFGSEGFREICPAGPGYHYSA 402
CQ GF CP G H+++
Sbjct: 2496 CQFLCVNTIGGFTCKCPPGFTQHHTS 2521
Score = 66.2 bits (160), Expect = 2e-10
Identities = 32/86 (37%), Positives = 46/86 (53%), Gaps = 5/86 (5%)
Query: 1466 EAEECGIL-DGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1524
+ +EC ++ D C NG CV + C C GY D+T +CVD+NEC++A P N
Sbjct: 2402 DIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQA----PKPCNF 2457
Query: 1525 RCLNTDGSFRCICRPGFAPTHQPHHC 1550
C NT+GS++C C G+ C
Sbjct: 2458 ICKNTEGSYQCSCPKGYILQEDGRSC 2483
Score = 63.9 bits (154), Expect = 1e-09
Identities = 34/77 (44%), Positives = 40/77 (51%), Gaps = 4/77 (5%)
Query: 1466 EAEECGI-LDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1524
+ EC + D C NG C + + C C GY +D T CVDINEC S LC N
Sbjct: 723 DINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINEC---VLNSLLCDNG 779
Query: 1525 RCLNTDGSFRCICRPGF 1541
+C NT GSF C C GF
Sbjct: 780 QCRNTPGSFVCTCPKGF 796
Score = 62.0 bits (149), Expect = 4e-09
Identities = 29/91 (31%), Positives = 41/91 (45%), Gaps = 4/91 (4%)
Query: 1466 EAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1524
+ +EC + G C G C+ F C+C G++L+ C DI+EC +C
Sbjct: 246 DVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPG---ICEGG 302
Query: 1525 RCLNTDGSFRCICRPGFAPTHQPHHCAPARP 1555
C NT S+ C C PGF + C RP
Sbjct: 303 ECTNTVSSYFCKCPPGFYTSPDGTRCIDVRP 333
Score = 53.1 bits (126), Expect = 2e-06
Identities = 25/74 (33%), Positives = 37/74 (50%), Gaps = 5/74 (6%)
Query: 1477 TNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCI 1536
+ G C P FTC C G+ LD T +C D++EC+ + C + C N G +RC
Sbjct: 2537 SKGICQNTPGSFTCECQRGFSLDQTGSSCEDVDECE----GNHRCQHG-CQNIIGGYRCS 2591
Query: 1537 CRPGFAPTHQPHHC 1550
C G+ +Q + C
Sbjct: 2592 CPQGYLQHYQWNQC 2605
Score = 52.0 bits (123), Expect = 4e-06
Identities = 28/76 (36%), Positives = 37/76 (48%), Gaps = 5/76 (6%)
Query: 1466 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNAR 1525
+ +EC C +G C + G+ C C GY CVD NEC A +C A
Sbjct: 2567 DVDECEGNHRCQHG-CQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAH----ICGGAS 2621
Query: 1526 CLNTDGSFRCICRPGF 1541
C NT GS++C+C GF
Sbjct: 2622 CHNTLGSYKCMCPAGF 2637
Score = 48.5 bits (114), Expect = 5e-05
Identities = 25/84 (29%), Positives = 36/84 (42%), Gaps = 4/84 (4%)
Query: 1465 LEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1524
++ EC C C + C C G++ + C DINEC A+A +
Sbjct: 2606 VDENECLSAHICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAP----CSY 2661
Query: 1525 RCLNTDGSFRCICRPGFAPTHQPH 1548
C NT+G + C C PG+ Q H
Sbjct: 2662 GCSNTEGGYLCGCPPGYFRIGQGH 2685
Score = 38.1 bits (87), Expect = 0.067
Identities = 22/50 (44%), Positives = 28/50 (56%), Gaps = 6/50 (12%)
Query: 1492 CFDGY-RLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPG 1540
C GY R+ T+ C DI+EC E +C N C+NT GSF+C C G
Sbjct: 896 CGKGYSRIKGTQ--CEDIDEC---EVFPGVCKNGLCVNTRGSFKCQCPSG 940
Score = 36.6 bits (83), Expect = 0.19
Identities = 22/74 (29%), Positives = 30/74 (40%), Gaps = 14/74 (18%)
Query: 41 CGLRCVHGPTGSRCTPTCAPRNATSVDSGAPGGAAPGGPGFRAFLCPLICHNGGVCVKPD 100
C +RC++G + S C + G P +C C NGG CV P+
Sbjct: 119 CNIRCMNGGSCSDDHCLCQ-KGYIGTHCGQP-------------VCESGCLNGGRCVAPN 164
Query: 101 RCLCPPDFAGKFCQ 114
RC C F G C+
Sbjct: 165 RCACTYGFTGPQCE 178
Score = 34.3 bits (77), Expect = 0.96
Identities = 17/45 (37%), Positives = 23/45 (51%), Gaps = 5/45 (11%)
Query: 1507 DINECDEAEAASP-LCVNARCLNTDGSFRCICRPGFAPTHQPHHC 1550
DINEC A P +C N C N G+++CIC G+ +C
Sbjct: 723 DINEC----ALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNC 763
Score = 32.0 bits (71), Expect = 4.8
Identities = 19/61 (31%), Positives = 25/61 (40%), Gaps = 8/61 (13%)
Query: 1449 PEGGSYAGSL--AEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACV 1506
P+G Y L E +E E+ C NG C P F C C LD T+ C+
Sbjct: 793 PKGFIYKPDLKTCEDIDECESSPC------INGVCKNSPGSFICECSSESTLDPTKTICI 846
Query: 1507 D 1507
+
Sbjct: 847 E 847
>gi|66346695 fibrillin 2 precursor [Homo sapiens]
Length = 2912
Score = 525 bits (1352), Expect = e-148
Identities = 427/1480 (28%), Positives = 591/1480 (39%), Gaps = 232/1480 (15%)
Query: 220 GYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPT 279
G C+ ++ C + G + CC G AWG C+ C D CP
Sbjct: 896 GTCWLNIQDSRCEVNINGATLKSECCATLGAAWG-SPCERCEL-----------DTACPR 943
Query: 280 GFERVNG-SCEDVDECAT-GGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISE 337
G R+ G +CEDV+EC G C +G C N++G + C CP+G LD + C+ +
Sbjct: 944 GLARIKGVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQ- 1002
Query: 338 AKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREICPAGPG 397
C+ + C P+ CCC+ VG AWG C+ CP G++ + +CP G G
Sbjct: 1003 ----CYLKWDEDECIHPVPGKFRMDACCCA-VGAAWGTECEECPKPGTKEYETLCPRGAG 1057
Query: 398 YHYSASDLRYNTRPLGQE-------PPRVSLSQPRTLPAT--SRPSAGF---LPTHRLEP 445
+ L RP ++ P + + R + R ++GF +
Sbjct: 1058 FANRGDVL--TGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTD 1115
Query: 446 RPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRN----------PQVCGPGRCI 495
E R P + P E E S M +N P +C G C+
Sbjct: 1116 IDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCRGGTCV 1175
Query: 496 SRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGP 555
+ + C C G LSP C+D++EC C G+C N G+++C C PG++A P
Sbjct: 1176 NTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATP 1235
Query: 556 RAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLC 615
C D+DEC + CD +C N+ GS+ C C GY P G SC D+DEC +P +C
Sbjct: 1236 DRQGCTDIDECMIMNGGCDT-QCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDIC 1294
Query: 616 GRGACKNLPGSFRCVCPAGFRGSACEE---DVDECAQEPPPCGPGRCDNTAGSFHCACPA 672
G C N+PG +RC+C GF S + DV+EC C G C+NT GSF C C
Sbjct: 1295 DGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQL 1354
Query: 673 GFRSRGPGAPCQDVDECARSPPPC-TYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDEC 731
G+ + C DVDEC C + C N GSF+C C G+ N G +C D+DEC
Sbjct: 1355 GYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGN--GIKCIDLDEC 1412
Query: 732 EN--HLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEG 789
N H +CVN+PGS++C C G C+DVDEC+ C +G C N G
Sbjct: 1413 SNGTHQCSINAQCVNTPGSYRC-ACSEGFTGDGFTCSDVDECAENINLC-ENGQCLNVPG 1470
Query: 790 SFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGA 849
++RC C G+ P+ C D++EC + C G C N G F C C GY G
Sbjct: 1471 AYRCECEMGF-TPASDSRSCQDIDECSFQNICV-FGTCNNLPGMFHCICDDGYELDRTGG 1528
Query: 850 SCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLD--VDECRER-GPALC 906
+C D+DEC++ C +G+C NT G +EC CPP + P C+D V C + GP
Sbjct: 1529 NCTDIDECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGD 1588
Query: 907 GSQRC--ENSPGSYRCVRDCDPGYHAG-PEGTC--------------------------- 936
GS C E G R C G G P TC
Sbjct: 1589 GSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITIIL 1648
Query: 937 DDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGG-CQDVDEC-RNRSFCGA 994
+D+DECQE P +C C NT GS++C C GY + C+D+DEC + CG
Sbjct: 1649 EDIDECQEL-PGLCQGGNCINTFGSFQC--ECPQGYYLSEDTRICEDIDECFAHPGVCGP 1705
Query: 995 HAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCE-----NVEGSFLC 1049
C N G++ C+C Y G +C+D+ + + G CE NV C
Sbjct: 1706 -GTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTT-CENELPFNVTKRMCC 1763
Query: 1050 VCPNSPEEFDPMTGRCVPP-----RTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTP 1104
N + ++ C P +T G PG + P
Sbjct: 1764 CTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDI----DECKEIPGIC 1819
Query: 1105 RQG----PVGSGRREC-----YFDTAAP----DAC---DNILARNVTW------QECCCT 1142
G +GS R EC Y D D C DN+ RN C C
Sbjct: 1820 ANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCECA 1879
Query: 1143 VGEGWG-SGCRIQQCPGTETAEYQSLCPHG--------------RGYLAPSGDLSLRRDV 1187
G +G + + E E ++C HG G+ A S D ++ DV
Sbjct: 1880 AGFKLSPNGACVDR---NECLEIPNVCSHGLCVDLQGSYQCICHNGFKA-SQDQTMCMDV 1935
Query: 1188 DECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECAD-EEPACEGGRCV 1246
DEC+ C +G C NT Y+C C G+ T +C+D DEC+ C GRC
Sbjct: 1936 DECE---RHPCGNGTCKNTVGSYNCLCYPGFEL-THNNDCLDIDECSSFFGQVCRNGRCF 1991
Query: 1247 NTVGSYHCTCEPPLVLDGSQRRCV-SNESQSLDDNL--GVCWQEVGADLVCSHP-----R 1298
N +GS+ C C L + C+ +NE +L + G C Q + C P +
Sbjct: 1992 NEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTC-QNLEGSFRCICPPGYEVK 2050
Query: 1299 LDRQATYTEC-----CCLYGEA----WGMDCALCPAQD--SDDFEALCNVLRPPAYSPPR 1347
+ EC CL+G G C LCP SD+ + + ++
Sbjct: 2051 SENCIDINECDEDPNICLFGSCTNTPGGFQC-LCPPGFVLSDNGRRCFDTRQSFCFTNFE 2109
Query: 1348 PGGFGLPYEYGPDLGPPYQGLPYGPELYPPPALPYDPYPPPPGPFARREAPYGAPRFDMP 1407
G +P + G P L P+ D
Sbjct: 2110 NGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCEL--------------------CPKDDEV 2149
Query: 1408 DFEDDGGPYGESEAPAPPGPGTRWPYRSRDTRRSFPEPEEPP----------EGGSYAGS 1457
F+ D PYG P+ DTR E E P GS+
Sbjct: 2150 AFQ-DLCPYGHGTVPS-----------LHDTREDVNECLESPGICSNGQCINTDGSFRCE 2197
Query: 1458 LAEPYE-ELEAEECGILDGCT------NGRCVRVPEGFTCRCFDGYRLDMTRMACVDINE 1510
Y + C D C+ NG C V F C C +G+ M C DINE
Sbjct: 2198 CPMGYNLDYTGVRCVDTDECSIGNPCGNGTCTNVIGSFECNCNEGFE-PGPMMNCEDINE 2256
Query: 1511 CDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHC 1550
C A +PL RC+NT GS+ C C G+A C
Sbjct: 2257 C----AQNPLLCAFRCMNTFGSYECTCPIGYALREDQKMC 2292
Score = 491 bits (1264), Expect = e-138
Identities = 338/1034 (32%), Positives = 471/1034 (45%), Gaps = 139/1034 (13%)
Query: 277 CPTGFERVNGS--CEDVDEC-ATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQH 333
CP G+ + CED+DEC A G C G C NT G YTC+CP ++ + +C+
Sbjct: 1677 CPQGYYLSEDTRICEDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMR 1736
Query: 334 VISEAKGPCFRVLRDGGCSLPILRNITKQICCCS-RVGKAWGRGCQLCPPFGSEGFREIC 392
K C+R C + N+TK++CCC+ VGKAW + C+ CP G+ F+ IC
Sbjct: 1737 -----KSFCYRSYNGTTCENELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTIC 1791
Query: 393 PAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPD 452
PG+ + + V + + + +P A + +++ P
Sbjct: 1792 GNIPGFTFDIHTGK-----------AVDIDECKEIPGIC---ANGVCINQIGSFRCECPT 1837
Query: 453 PRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLS 512
+L L +I E +CQRN CI+ P Y C C +GF+LS
Sbjct: 1838 GFSYNDLLLVC------EDIDECSNGDNLCQRNAD------CINSPGSYRCECAAGFKLS 1885
Query: 513 PQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPP 572
P G C+D +EC +P C+ G C + GS++C+C GF+A C+DVDEC R P
Sbjct: 1886 PNGA-CVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDECER--HP 1942
Query: 573 CDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPG-LCGRGACKNLPGSFRCVC 631
C G C+NT GS+ C+C G++ H C D+DEC+ G +C G C N GSF+C+C
Sbjct: 1943 CGNGTCKNTVGSYNCLCYPGFELT-HNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLC 2001
Query: 632 PAGFR----GSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVD 687
G+ G C D +EC P C PG C N GSF C CP G+ + C D++
Sbjct: 2002 NEGYELTPDGKNCI-DTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSEN--CIDIN 2058
Query: 688 ECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPG 747
EC P C +G C NT G FQC+CP GF + G C D + C +
Sbjct: 2059 ECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQ---------SFCFTNFE 2109
Query: 748 SFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCT----NTEGSFRCSCAPGYRAPS 803
+ +C + P + + +C C S P G C + E +F+ C G+
Sbjct: 2110 NGKC-SVPKAFNTTKAKC-----CCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVP 2163
Query: 804 GRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLC 863
DVNECLE +G+C+NTDGSF C C GY G C+D DECS + C
Sbjct: 2164 SLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPC 2223
Query: 864 QSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRD 923
+G CTN GSFEC C G GP + +C D++EC + P LC + RC N+ GSY C
Sbjct: 2224 GNGTCTNVIGSFECNCNEGFEPGP-MMNCEDINECAQ-NPLLC-AFRCMNTFGSYECT-- 2278
Query: 924 CDPGYH-AGPEGTCDDVDECQEYGPEICGAQ--RCENTPGSYRCTPACDPGYQPTPGG-G 979
C GY + C D+DEC E G C ++ C+N G++ C C PG P G G
Sbjct: 2279 CPIGYALREDQKMCKDLDECAE-GLHDCESRGMMCKNLIGTFMC--ICPPGMARRPDGEG 2335
Query: 980 CQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNE----CETLQGVC 1035
C D +ECR + + C N+ GS++C C++G++ + G C+D + E LQ +C
Sbjct: 2336 CVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTIC 2395
Query: 1036 G-AALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPP 1094
A+ N+ C C GR + PG+ A + P P
Sbjct: 2396 QMASSSRNLVTKSECCCDG---------GRGWGHQCELCPLPGT---AQYKKICPHGP-- 2441
Query: 1095 PPLPRRPSTPRQGPVGSGR--RECYFDTAAPDACDNILARNVTWQ-ECCCTVG---EGWG 1148
G GR EC P+ C N N C C VG + G
Sbjct: 2442 ------------GYTTDGRDIDEC---KVMPNLCTNGQCINTMGSFRCFCKVGYTTDISG 2486
Query: 1149 SGC----RIQQ--------CPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQ 1196
+ C Q C TE YQ CP RGY+ D +D+DECQ +
Sbjct: 2487 TSCIDLDECSQSPKPCNYICKNTE-GSYQCSCP--RGYVLQE-DGKTCKDLDECQT-KQH 2541
Query: 1197 VCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEG-GRCVNTVGSYHCT 1255
C+ +CVNT G++C C G+ H CIDN+EC + C G C NT GS+ C
Sbjct: 2542 NCQF-LCVNTLGGFTCKCPPGFTQH--HTACIDNNECGSQPSLCGAKGICQNTPGSFSCE 2598
Query: 1256 CEPPLVLDGSQRRC 1269
C+ LD + C
Sbjct: 2599 CQRGFSLDATGLNC 2612
Score = 479 bits (1234), Expect = e-135
Identities = 311/967 (32%), Positives = 414/967 (42%), Gaps = 144/967 (14%)
Query: 482 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDV-------------------- 521
C+ NP C G C + + C C G +LS G CID
Sbjct: 856 CESNP--CVNGACRNNLGSFNCECSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNING 913
Query: 522 ----DECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGR 577
EC CE C P A + C DV+EC P C GR
Sbjct: 914 ATLKSECCATLGAAWGSPCERCELDTAC---PRGLARIKGVTCEDVNECEVFPGVCPNGR 970
Query: 578 CENTPGSFLCVCPAGYQAAPHGASCQDV-----------DECTQS-PG-------LCGRG 618
C N+ GSF C CP G G C D+ DEC PG C G
Sbjct: 971 CVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAVG 1030
Query: 619 A-----CKNLPG----SFRCVCPAG---------FRGSACEEDVDECAQEPPPCGPGRCD 660
A C+ P + +CP G G +D++EC P C G+C
Sbjct: 1031 AAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGKCR 1090
Query: 661 NTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPN- 719
NT GSF C C +GF C D+DEC SP C G C NT GSF+C C G++
Sbjct: 1091 NTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFECECFEGYESGF 1150
Query: 720 TAGSECEDVDECE-NHLACPGQECVNSPGSFQCRTCPSGHHLHRGR--CTDVDECSSGAP 776
C D+DECE N L C G CVN+ GSFQC CP GH L R C D++ECS
Sbjct: 1151 MMMKNCMDIDECERNPLLCRGGTCVNTEGSFQC-DCPLGHELSPSREDCVDINECSLSDN 1209
Query: 777 PCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECL-EGDFCFPHGECLNTDGSFA 835
C +G C N G+++CSC PGY+A R G C D++EC+ C +C N++GS+
Sbjct: 1210 LCR-NGKCVNMIGTYQCSCNPGYQATPDRQG-CTDIDECMIMNGGC--DTQCTNSEGSYE 1265
Query: 836 CTCAPGYRPGPRGASCLDVDECSEE-DLCQSGICTNTDGSFECICPPGHRAGPDLASCLD 894
C+C+ GY P G SC D+DEC D+C G CTN G + C+C G A D+ +C+D
Sbjct: 1266 CSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCID 1325
Query: 895 VDECRERGPALCGSQRCENSPGSYRC-----------------VRDCDPGYH-------- 929
V+EC + +C CEN+ GS+ C V +C+ G H
Sbjct: 1326 VNEC-DLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASC 1384
Query: 930 ---------------AGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQP 974
G C D+DEC + +C NTPGSYRC AC G+
Sbjct: 1385 LNIPGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRC--ACSEGFTG 1442
Query: 975 TPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGV 1034
G C DVDEC + C N+PG+++C C+ G+ A D R C D++EC + Q +
Sbjct: 1443 D-GFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDEC-SFQNI 1500
Query: 1035 CGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPP 1094
C C N+ G F C+C + E D G C A +P P
Sbjct: 1501 CVFGTCNNLPGMFHCICDDG-YELDRTGGNCTDIDECADPINCVNGLCVNTPGRYECNCP 1559
Query: 1095 PPLPRRPSTPRQGPVGSGRRECYFDTAAPD----ACDNILARNVTWQECCCTVGEGWGSG 1150
P P+ G V + CY +C+ + V+ CCC++G+ WG+
Sbjct: 1560 PDFQLNPTGV--GCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNP 1617
Query: 1151 CRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGY 1210
C + CP + EY +LCP G G+ P+ + D+DECQ +C+ G C+NT +
Sbjct: 1618 C--ETCPPVNSTEYYTLCPGGEGF-RPNPITIILEDIDECQELPG-LCQGGNCINTFGSF 1673
Query: 1211 SCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCV 1270
C C GYY C D DEC C G C NT+G+Y C C P + C
Sbjct: 1674 QCECPQGYYLSEDTRICEDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNC- 1732
Query: 1271 SNESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLY--GEAWGMDCALCPAQDS 1328
+D C++ C + L T CCC Y G+AW C CP +
Sbjct: 1733 ------MDMRKSFCYRSYNG-TTCEN-ELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGT 1784
Query: 1329 DDFEALC 1335
DF+ +C
Sbjct: 1785 ADFKTIC 1791
Score = 472 bits (1214), Expect = e-132
Identities = 368/1217 (30%), Positives = 501/1217 (41%), Gaps = 201/1217 (16%)
Query: 244 CCRG-AGLAWGVHDCQLCSERLG---NSERVSAPDG---PCPTGFERVNGS--CEDVDEC 294
C G G + D C+E + N + ++ P C GF + S C+D+DEC
Sbjct: 1436 CSEGFTGDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDEC 1495
Query: 295 ATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCIS----QHVISEAKGPCFRVLRDGG 350
+ C G C N G + C+C DG+ LD + +C I+ G C
Sbjct: 1496 SFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECADPINCVNGLCVNTPGRYE 1555
Query: 351 CSLP--ILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREI-CPAGPGYHYSASDLRY 407
C+ P N T C +RVG + + FG G + C G S S
Sbjct: 1556 CNCPPDFQLNPTGVGCVDNRVGNCYLK-------FGPRGDGSLSCNTEIGVGVSRSSCC- 1607
Query: 408 NTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAW 467
SL + P + P + L P E RP P +
Sbjct: 1608 -----------CSLGKAWGNPCETCPPVNSTEYYTLCPGGEGF---RPNPITIILE---- 1649
Query: 468 TGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRV 527
+I E CQ P +C G CI+ + C C G+ LS C D+DEC
Sbjct: 1650 ---DIDE-------CQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAH 1699
Query: 528 PPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDE--CHR---------------VP 570
P C PG C N+ G++ C+C P + C+D+ + C+R
Sbjct: 1700 PGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTK 1759
Query: 571 PPC----DLGRCEN-------TPGS--FLCVCP--AGYQAAPHGASCQDVDECTQSPGLC 615
C ++G+ N TPG+ F +C G+ H D+DEC + PG+C
Sbjct: 1760 RMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKEIPGIC 1819
Query: 616 GRGACKNLPGSFRCVCPAGFRGS----ACEEDVDECAQEPPPCGPGR-CDNTAGSFHCAC 670
G C N GSFRC CP GF + C ED+DEC+ C C N+ GS+ C C
Sbjct: 1820 ANGVCINQIGSFRCECPTGFSYNDLLLVC-EDIDECSNGDNLCQRNADCINSPGSYRCEC 1878
Query: 671 PAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDE 730
AGF+ P C D +EC P C++G C + +GS+QC+C GF+ + + C DVDE
Sbjct: 1879 AAGFK-LSPNGACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDE 1937
Query: 731 CENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGS 790
CE H C C N+ GS+ C P H C D+DECSS +G C N GS
Sbjct: 1938 CERH-PCGNGTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRNGRCFNEIGS 1996
Query: 791 FRCSCAPGYR-APSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGA 849
F+C C GY P G+ C D NEC+ G C N +GSF C C PGY +
Sbjct: 1997 FKCLCNEGYELTPDGK--NCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGYE--VKSE 2052
Query: 850 SCLDVDECSEE-DLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDEC-----RERG- 902
+C+D++EC E+ ++C G CTNT G F+C+CPPG + C D + E G
Sbjct: 2053 NCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGK 2112
Query: 903 ---PALCGSQR----CENSPGS------YRCVRD--------CDPGYHAGP--EGTCDDV 939
P + + C PG C +D C G+ P T +DV
Sbjct: 2113 CSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDV 2172
Query: 940 DECQEYGPEICGAQRCENTPGSYRCTPACDPGYQ-PTPGGGCQDVDECRNRSFCGAHAVC 998
+EC E P IC +C NT GS+RC C GY G C D DEC + CG + C
Sbjct: 2173 NECLE-SPGICSNGQCINTDGSFRC--ECPMGYNLDYTGVRCVDTDECSIGNPCG-NGTC 2228
Query: 999 QNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCP------ 1052
N+ GSF+C C++G+E +C D+NEC +C A C N GS+ C CP
Sbjct: 2229 TNVIGSFECNCNEGFEPG-PMMNCEDINECAQNPLLC-AFRCMNTFGSYECTCPIGYALR 2286
Query: 1053 ----------NSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARP------PPPP 1096
E R + + GTF P P + RP
Sbjct: 2287 EDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICP-----PGMARRPDGEGCVDENE 2341
Query: 1097 LPRRPSTPRQGP----VGSGRREC----YFDTAAPDACDN-----------------ILA 1131
+P G +GS R EC ++ + DN +
Sbjct: 2342 CRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSS 2401
Query: 1132 RN-VTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDEC 1190
RN VT ECCC G GWG C + CP TA+Y+ +CPHG GY RD+DEC
Sbjct: 2402 RNLVTKSECCCDGGRGWGHQCEL--CPLPGTAQYKKICPHGPGYTTDG------RDIDEC 2453
Query: 1191 QLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVG 1250
++ +C +G C+NT + C+C GY CID DEC+ C C NT G
Sbjct: 2454 KVM-PNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPC-NYICKNTEG 2511
Query: 1251 SYHCTCEPPLVLDGSQRRCVS-NESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTECC 1309
SY C+C VL + C +E Q+ N C P T
Sbjct: 2512 SYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCP---PGFTQHHTA 2568
Query: 1310 CLYGEAWGMDCALCPAQ 1326
C+ G +LC A+
Sbjct: 2569 CIDNNECGSQPSLCGAK 2585
Score = 457 bits (1176), Expect = e-128
Identities = 378/1272 (29%), Positives = 507/1272 (39%), Gaps = 309/1272 (24%)
Query: 220 GYCFRELRGGECASPLPGLR-TQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAP----- 273
G CF ++ C L G+ T+ +CC G AWG H C++C + R P
Sbjct: 214 GPCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAWG-HPCEMCPAQPQPCRRGFIPNIRTG 272
Query: 274 ---------------------------DGPCPTGFER--VNGSCEDVDECAT-GGRCQHG 303
+ CP G ++ CED+DEC+ G C+ G
Sbjct: 273 ACQDVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETG 332
Query: 304 ECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQI 363
EC+NT G Y CVCP G++ + S CI Q G CF L +G C+ + +TK
Sbjct: 333 ECSNTVGSYFCVCPRGYVTSTDGSRCIDQRT-----GMCFSGLVNGRCAQELPGRMTKMQ 387
Query: 364 CCCSRVGKAWGRGC--QLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVSL 421
CCC G+ WG G + CP GSE +R +C G P+G P
Sbjct: 388 CCC-EPGRCWGIGTIPEACPVRGSEEYRRLCMDG--------------LPMGGIPG---- 428
Query: 422 SQPRTLPATSRPSA----GFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGP 477
A SRP GF P+ P +P+P ++ P + +G
Sbjct: 429 ------SAGSRPGGTGGNGFAPSGNGNGY-----GPGGTGFIPIPGGNGFS-PGVGGAGV 476
Query: 478 SSG-----------------MCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCID 520
+G +C+ + +C GRCI S Y C C+ G++ G CID
Sbjct: 477 GAGGQGPIITGLTILNQTIDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANGD-CID 535
Query: 521 VDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCEN 580
VDEC PC G C N+PGS+ C C GF+ P C+D+DEC + C GRC N
Sbjct: 536 VDEC--TSNPCTNGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVN 593
Query: 581 TPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGF----R 636
T GSF C+C AG++ G +C D DECT + +C G C N GSF+C+C GF
Sbjct: 594 TDGSFQCICNAGFELTTDGKNCVDHDECT-TTNMCLNGMCINEDGSFKCICKPGFVLAPN 652
Query: 637 GSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDV---------- 686
G C DVDEC Q P C G C N+ GSF C CP G G C D
Sbjct: 653 GRYC-TDVDEC-QTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGI 710
Query: 687 ---------------DECARSPP------PCT----------YGRCENTEG--------- 706
EC + P PC +G C + G
Sbjct: 711 KKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGRDIN 770
Query: 707 -------------------SFQCVCPMGFQPNTAGSECEDVDEC-ENHLACPGQECVNSP 746
S++C C G++P+ +G C D+DEC N L C C N+P
Sbjct: 771 ECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTP 830
Query: 747 GSFQCRTCPSGH--HLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPS- 803
GS+ C TCP G+ C D++EC S PC +G C N GSF C C+PG + S
Sbjct: 831 GSYSC-TCPPGYVFRTETETCEDINECESN--PC-VNGACRNNLGSFNCECSPGSKLSST 886
Query: 804 ------GRPGPC--------ADVN---ECLEGDFCFPHG-----ECLNTDGSFACTCAPG 841
G C +VN L+ + C G C + AC P
Sbjct: 887 GLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCERCELDTAC---PR 943
Query: 842 YRPGPRGASCLDVDECSE-EDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDV----- 895
+G +C DV+EC +C +G C N+ GSF C CP G CLD+
Sbjct: 944 GLARIKGVTCEDVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQC 1003
Query: 896 ------DEC------RERGPALC------GSQRCEN--SPGSYRCVRDCDPGYHAGPEGT 935
DEC + R A C CE PG+ C G G
Sbjct: 1004 YLKWDEDECIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGD 1063
Query: 936 C-------DDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQ-PTPGGGCQDVDECR 987
D++EC+ + P +C +C NT GS++C C+ G+ C D+DECR
Sbjct: 1064 VLTGRPFYKDINECKAF-PGMCTYGKCRNTIGSFKC--RCNSGFALDMEERNCTDIDECR 1120
Query: 988 -NRSFCGAHAVCQNLPGSFQCLCDQGYE-GARDGRHCVDVNECETLQGVCGAALCENVEG 1045
+ CG+ +C N PGSF+C C +GYE G ++C+D++ECE +C C N EG
Sbjct: 1121 ISPDLCGS-GICVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNTEG 1179
Query: 1046 SFLCVCP----NSPEEFDPM-------------TGRCVPPRTSAGTFPGSQPQAPASPVL 1088
SF C CP SP D + G+CV GT+ Q +P
Sbjct: 1180 SFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCV---NMIGTY-----QCSCNPGY 1231
Query: 1089 PARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGW- 1147
A P RQG EC CD + EC C+ G
Sbjct: 1232 QATP-----------DRQGCTDID--ECMIMNG---GCDTQCTNSEGSYECSCSEGYALM 1275
Query: 1148 --GSGCR-IQQCPGTE-----------TAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLF 1193
G C I +C EY+ LC G S D+ DV+EC L
Sbjct: 1276 PDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDG---FMASMDMKTCIDVNECDL- 1331
Query: 1194 RDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACE-GGRCVNTVGSY 1252
+C G C NT + C+C GY C D DEC C+ C+N GS+
Sbjct: 1332 NSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSF 1391
Query: 1253 HCTCEPPLVLDG 1264
C+C + +G
Sbjct: 1392 KCSCREGWIGNG 1403
Score = 441 bits (1134), Expect = e-123
Identities = 295/908 (32%), Positives = 393/908 (43%), Gaps = 126/908 (13%)
Query: 482 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPG 541
C N +C G+C++ P Y C C+ GF + C D+DEC C G C N PG
Sbjct: 1453 CAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECS-FQNICVFGTCNNLPG 1511
Query: 542 SFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGAS 601
F C+C G+ C D+DEC P C G C NTPG + C CP +Q P G
Sbjct: 1512 MFHCICDDGYELDRTGGNCTDIDECAD-PINCVNGLCVNTPGRYECNCPPDFQLNPTGVG 1570
Query: 602 CQD--VDECTQSPGLCGRGA---------------------------CKNLPG----SFR 628
C D V C G G G+ C+ P +
Sbjct: 1571 CVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYY 1630
Query: 629 CVCPAG--FRGSACE---EDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPC 683
+CP G FR + ED+DEC + P C G C NT GSF C CP G+ C
Sbjct: 1631 TLCPGGEGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRIC 1690
Query: 684 QDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECV 743
+D+DEC P C G C NT G++ C+CP + G C D+ + + + G C
Sbjct: 1691 EDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCE 1750
Query: 744 NS-PGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAP 802
N P + R C C + + PC P + C PG+
Sbjct: 1751 NELPFNVTKRMC----------CCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFD 1800
Query: 803 SGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEED- 861
G D++EC E +G C+N GSF C C G+ C D+DECS D
Sbjct: 1801 I-HTGKAVDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDN 1859
Query: 862 LCQSGI-CTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRC 920
LCQ C N+ GS+ C C G + P+ +C+D +EC E P +C C + GSY+C
Sbjct: 1860 LCQRNADCINSPGSYRCECAAGFKLSPN-GACVDRNECLEI-PNVCSHGLCVDLQGSYQC 1917
Query: 921 VRDCDPGYHAGPEGT-CDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGG 979
+ C G+ A + T C DVDEC+ + CG C+NT GSY C C PG++ T
Sbjct: 1918 I--CHNGFKASQDQTMCMDVDECERHP---CGNGTCKNTVGSYNCL--CYPGFELTHNND 1970
Query: 980 CQDVDECRNRSFCGA---HAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCG 1036
C D+DEC SF G + C N GSF+CLC++GYE DG++C+D NEC L G C
Sbjct: 1971 CLDIDECS--SFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCS 2028
Query: 1037 AALCENVEGSFLCVCPNSPE------------EFDP---MTGRCVPPRTSAGTFPGSQPQ 1081
C+N+EGSF C+CP E + DP + G C T G Q
Sbjct: 2029 PGTCQNLEGSFRCICPPGYEVKSENCIDINECDEDPNICLFGSCT------NTPGGFQCL 2082
Query: 1082 APASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCC 1141
P VL RR RQ F C A N T +CCC
Sbjct: 2083 CPPGFVLSDNG------RRCFDTRQS--------FCFTNFENGKCSVPKAFNTTKAKCCC 2128
Query: 1142 TV--GEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCK 1199
+ GEGWG C + CP + +Q LCP+G G + D R DV+EC L +C
Sbjct: 2129 SKMPGEGWGDPCEL--CPKDDEVAFQDLCPYGHGTVPSLHDT--REDVNEC-LESPGICS 2183
Query: 1200 SGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPP 1259
+G C+NT + C C GY + C+D DEC+ P C G C N +GS+ C C
Sbjct: 2184 NGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNP-CGNGTCTNVIGSFECNCNEG 2242
Query: 1260 LVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLYGEAWGMD 1319
G C +++ C Q L+C+ ++ +Y EC C G A D
Sbjct: 2243 FE-PGPMMNC---------EDINECAQN---PLLCAFRCMNTFGSY-ECTCPIGYALRED 2288
Query: 1320 CALCPAQD 1327
+C D
Sbjct: 2289 QKMCKDLD 2296
Score = 417 bits (1073), Expect = e-116
Identities = 300/911 (32%), Positives = 392/911 (43%), Gaps = 192/911 (21%)
Query: 482 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPG 541
C P VC G C+ Y C C +GF+ S T C+DVDEC R PC G C+N+ G
Sbjct: 1896 CLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDECER--HPCGNGTCKNTVG 1953
Query: 542 SFRCVCGPGFRAGPRAAECLDVDECHRV-PPPCDLGRCENTPGSFLCVCPAGYQAAPHGA 600
S+ C+C PGF +CLD+DEC C GRC N GSF C+C GY+ P G
Sbjct: 1954 SYNCLCYPGFEL-THNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGK 2012
Query: 601 SCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGF--RGSACEEDVDECAQEPPPCGPGR 658
+C D +EC PG C G C+NL GSFRC+CP G+ + C D++EC ++P C G
Sbjct: 2013 NCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSENCI-DINECDEDPNICLFGS 2071
Query: 659 CDNTAGSFHCACPAGFRSRGPGAPCQDVDE--------------------------CARS 692
C NT G F C CP GF G C D + C++
Sbjct: 2072 CTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKM 2131
Query: 693 PPPCTYGRCE----NTEGSFQCVCPMGFQPNTAGSEC-EDVDEC-ENHLACPGQECVNSP 746
P CE + E +FQ +CP G + + EDV+EC E+ C +C+N+
Sbjct: 2132 PGEGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICSNGQCINTD 2191
Query: 747 GSFQCRTCPSGHHL-HRG-RCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSG 804
GSF+C CP G++L + G RC D DECS G P CG +G CTN GSF C+C G+
Sbjct: 2192 GSFRCE-CPMGYNLDYTGVRCVDTDECSIGNP-CG-NGTCTNVIGSFECNCNEGFE---- 2244
Query: 805 RPGP---CADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEE- 860
PGP C D+NEC + C+NT GS+ CTC GY C D+DEC+E
Sbjct: 2245 -PGPMMNCEDINECAQNPLLCAF-RCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGL 2302
Query: 861 DLCQSG--ICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALC---------GSQ 909
C+S +C N G+F CICPPG PD C+D +ECR + P +C GS
Sbjct: 2303 HDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECRTK-PGICENGRCVNIIGSY 2361
Query: 910 RC------ENSPGSYRCVRD------------------------------CDPGYH---- 929
RC ++S C+ + CD G
Sbjct: 2362 RCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQ 2421
Query: 930 -----------------AGPEGTCD--DVDECQEYGPEICGAQRCENTPGSYRCTPACDP 970
GP T D D+DEC+ P +C +C NT GS+RC C
Sbjct: 2422 CELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVM-PNLCTNGQCINTMGSFRCF--CKV 2478
Query: 971 GYQPTPGG-GCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECE 1029
GY G C D+DEC ++S + +C+N GS+QC C +GY DG+ C D++EC+
Sbjct: 2479 GYTTDISGTSCIDLDEC-SQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQ 2537
Query: 1030 TLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLP 1089
T Q C LC N G F C CP F C+ GSQP + +
Sbjct: 2538 TKQHNC-QFLCVNTLGGFTCKCPPG---FTQHHTACIDNNEC-----GSQPSLCGAKGIC 2588
Query: 1090 ARPPPPPLPRRPSTPRQGPVGSGRRECY---------FDTAAPDACDNILARNVTWQECC 1140
P GS EC + D CD N Q C
Sbjct: 2589 QNTP----------------GSFSCECQRGFSLDATGLNCEDVDECDG----NHRCQHGC 2628
Query: 1141 CTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKS 1200
+ G+ GC +GY+ + VDE + C S
Sbjct: 2629 QNILGGYRCGCP-------------------QGYIQ---HYQWNQCVDENECSNPNACGS 2666
Query: 1201 GVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPL 1260
C NT Y C C +G+ + C D +EC+ + C G C NT G Y C C PP
Sbjct: 2667 ASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNPCNYG-CSNTEGGYLCGC-PPG 2724
Query: 1261 VLDGSQRRCVS 1271
Q CVS
Sbjct: 2725 YYRVGQGHCVS 2735
Score = 408 bits (1048), Expect = e-113
Identities = 304/979 (31%), Positives = 400/979 (40%), Gaps = 207/979 (21%)
Query: 485 NPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCID--VDECRRVPPP------------ 530
+P C G C++ P Y C C F+L+P G C+D V C P
Sbjct: 1538 DPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEI 1597
Query: 531 ----------CAPGR-----CENSPG----SFRCVC--GPGFRAGPRAAECLDVDECHRV 569
C+ G+ CE P + +C G GFR P D+DEC +
Sbjct: 1598 GVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQEL 1657
Query: 570 PPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRC 629
P C G C NT GSF C CP GY + C+D+DEC PG+CG G C N G++ C
Sbjct: 1658 PGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPGTCYNTLGNYTC 1717
Query: 630 VCPAGF------------RGSACEEDVD--ECAQEPP--------------------PCG 655
+CP + R S C + C E P PC
Sbjct: 1718 ICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTKRMCCCTYNVGKAWNKPCE 1777
Query: 656 PGRCDNTAG-SFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPM 714
P TA C GF D+DEC P C G C N GSF+C CP
Sbjct: 1778 PCPTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKEIPGICANGVCINQIGSFRCECPT 1837
Query: 715 GFQPNTAGSECEDVDECEN--HLACPGQECVNSPGSFQCRTCPSGHHLH-RGRCTDVDEC 771
GF N CED+DEC N +L +C+NSPGS++C C +G L G C D +EC
Sbjct: 1838 GFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCE-CAAGFKLSPNGACVDRNEC 1896
Query: 772 SSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTD 831
C HG C + +GS++C C G++A + C DV+EC E C +G C NT
Sbjct: 1897 LEIPNVCS-HGLCVDLQGSYQCICHNGFKASQDQT-MCMDVDEC-ERHPC-GNGTCKNTV 1952
Query: 832 GSFACTCAPGYRPGPRGASCLDVDECSE--EDLCQSGICTNTDGSFECICPPGHRAGPDL 889
GS+ C C PG+ CLD+DECS +C++G C N GSF+C+C G+ PD
Sbjct: 1953 GSYNCLCYPGFEL-THNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDG 2011
Query: 890 ASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEI 949
+C+D +EC P C C+N GS+RC+ C PGY E C D++EC E P I
Sbjct: 2012 KNCIDTNECVAL-PGSCSPGTCQNLEGSFRCI--CPPGYEVKSEN-CIDINECDE-DPNI 2066
Query: 950 CGAQRCENTPGSYRCTPACDPGYQPTPGGG-CQDVDECRNRSFC---------------- 992
C C NTPG ++C C PG+ + G C D +SFC
Sbjct: 2067 CLFGSCTNTPGGFQCL--CPPGFVLSDNGRRCFDT----RQSFCFTNFENGKCSVPKAFN 2120
Query: 993 --GAHAVCQNLPG----------------SFQCLCDQGYEGARDGRHCV--DVNECETLQ 1032
A C +PG +FQ LC G+ G H DVNEC
Sbjct: 2121 TTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGH-GTVPSLHDTREDVNECLESP 2179
Query: 1033 GVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPP-RTSAGTFPGSQPQAPASPVLPAR 1091
G+C C N +GSF C CP D RCV S G
Sbjct: 2180 GICSNGQCINTDGSFRCECPMG-YNLDYTGVRCVDTDECSIGN----------------- 2221
Query: 1092 PPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVG--EGWGS 1149
P G+G C N++ EC C G G
Sbjct: 2222 ----------------PCGNG------------TCTNVIGSF----ECNCNEGFEPGPMM 2249
Query: 1150 GCR-IQQCPGTET----------AEYQSLCPHGRGYLAPSGDLSLRRDVDEC-QLFRDQV 1197
C I +C Y+ CP G A D + +D+DEC + D
Sbjct: 2250 NCEDINECAQNPLLCAFRCMNTFGSYECTCPIG---YALREDQKMCKDLDECAEGLHDCE 2306
Query: 1198 CKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCE 1257
+ +C N + C C G C+D +EC + CE GRCVN +GSY C C
Sbjct: 2307 SRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECN 2366
Query: 1258 PPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRLDRQ-ATYTECCCLYGEAW 1316
+G Q S+ ++ LD+ G+C+ EV +C R T +ECCC G W
Sbjct: 2367 -----EGFQSS--SSGTECLDNRQGLCFAEV-LQTICQMASSSRNLVTKSECCCDGGRGW 2418
Query: 1317 GMDCALCPAQDSDDFEALC 1335
G C LCP + ++ +C
Sbjct: 2419 GHQCELCPLPGTAQYKKIC 2437
Score = 406 bits (1043), Expect = e-113
Identities = 345/1212 (28%), Positives = 476/1212 (39%), Gaps = 267/1212 (22%)
Query: 464 IPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRC----- 518
I + G + E+G CQ + GP RC C+ +R P T+
Sbjct: 171 IGTYCGQPVCENG-----CQNGGRCIGPNRCACVYGFTGPQCERDYRTGPCFTQVNNQMC 225
Query: 519 ---IDVDECRRVPPPCAPGR-----CENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVP 570
+ C + GR CE P + C GF R C DVDEC +P
Sbjct: 226 QGQLTGIVCTKTLCCATIGRAWGHPCEMCPAQPQ-PCRRGFIPNIRTGACQDVDECQAIP 284
Query: 571 PPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCV 630
C G C NT GSF C CPAG++ + C+D+DEC+ PG+C G C N GS+ CV
Sbjct: 285 GICQGGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETGECSNTVGSYFCV 344
Query: 631 CPAGF----RGSACEED----------VDECAQEPPP--------CGPGRCDNTAGSFHC 668
CP G+ GS C + CAQE P C PGRC G+
Sbjct: 345 CPRGYVTSTDGSRCIDQRTGMCFSGLVNGRCAQELPGRMTKMQCCCEPGRCWG-IGTIPE 403
Query: 669 ACPAG-----FRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCP---------- 713
ACP R G P + A S P T G G+ P
Sbjct: 404 ACPVRGSEEYRRLCMDGLPMGGIPGSAGSRPGGTGGNGFAPSGNGNGYGPGGTGFIPIPG 463
Query: 714 -MGFQPNTAGSEC----------------EDVDECENHL-ACPGQECVNSPGSFQCRTCP 755
GF P G+ + +D C++H C C+ + S++C C
Sbjct: 464 GNGFSPGVGGAGVGAGGQGPIITGLTILNQTIDICKHHANLCLNGRCIPTVSSYRCE-CN 522
Query: 756 SGHHLH-RGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGY-RAPSGRPGPCADVN 813
G+ G C DVDEC+S PC +G C NT GS+ C C G+ R P+ + C D++
Sbjct: 523 MGYKQDANGDCIDVDECTSN--PC-TNGDCVNTPGSYYCKCHAGFQRTPTKQ--ACIDID 577
Query: 814 ECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDG 873
EC++ +G C+NTDGSF C C G+ G +C+D DEC+ ++C +G+C N DG
Sbjct: 578 ECIQNGVLCKNGRCVNTDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMCINEDG 637
Query: 874 SFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPE 933
SF+CIC PG P+ C DVDEC+ P +C + C NS GS+RC DC PG G +
Sbjct: 638 SFKCICKPGFVLAPNGRYCTDVDECQT--PGICMNGHCINSEGSFRC--DCPPGLAVGMD 693
Query: 934 G-TCDDV-------------------------DECQEYGPEICGAQRCENTP--GSYRCT 965
G C D EC P+ + C+ P S
Sbjct: 694 GRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFH 753
Query: 966 PACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDV 1025
C G T G +D++EC A+ +C+NL GS++C C+ GYE GR+C+D+
Sbjct: 754 GLCSSGVGITVDG--RDINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDI 811
Query: 1026 NECETLQGVCGAALCENVEGSFLCVCP---------------NSPEEFDPMTGRCVPPRT 1070
+EC + +C LC N GS+ C CP N E + G C R
Sbjct: 812 DECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINECESNPCVNGAC---RN 868
Query: 1071 SAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNIL 1130
+ G+F SP + S+ + S + C+ + C+ +
Sbjct: 869 NLGSF-----NCECSP-----------GSKLSSTGLICIDSLKGTCWLN-IQDSRCEVNI 911
Query: 1131 ARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDEC 1190
ECC T+G WGS C E E + CP G LA ++ DV+EC
Sbjct: 912 NGATLKSECCATLGAAWGSPC--------ERCELDTACPRG---LARIKGVTC-EDVNEC 959
Query: 1191 QLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVG 1250
++F VC +G CVN+ + C C G
Sbjct: 960 EVF-PGVCPNGRCVNSKGSFHCECPEG--------------------------------- 985
Query: 1251 SYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCC 1310
L LDG+ R C LD + C+ + D C HP + + CCC
Sbjct: 986 ---------LTLDGTGRVC-------LDIRMEQCYLKWDED-ECIHP-VPGKFRMDACCC 1027
Query: 1311 LYGEAWGMDCALCPAQDSDDFEALCNVLRPPAYSPPRPGGFGLPYEYGPDLGPPYQGLPY 1370
G AWG +C CP + ++E LC PR GF + G G P+
Sbjct: 1028 AVGAAWGTECEECPKPGTKEYETLC----------PRGAGFA-------NRGDVLTGRPF 1070
Query: 1371 GPELYPPPALPYDPYPPPPGPFARREAPYGAPRFDMPDFE---DDGGPYGESEAPAPPGP 1427
++ A P YG R + F+ + G E
Sbjct: 1071 YKDINECKAFP-------------GMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDID 1117
Query: 1428 GTRWPYRSRDTRRSFPEPEEPPEGGSYAGSLAEPYEE--LEAEECGILDG-------CTN 1478
R S D S P GS+ E YE + + C +D C
Sbjct: 1118 ECR---ISPDLCGSGICVNTP---GSFECECFEGYESGFMMMKNCMDIDECERNPLLCRG 1171
Query: 1479 GRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICR 1538
G CV F C C G+ L +R CVDINEC + LC N +C+N G+++C C
Sbjct: 1172 GTCVNTEGSFQCDCPLGHELSPSREDCVDINEC---SLSDNLCRNGKCVNMIGTYQCSCN 1228
Query: 1539 PGFAPTHQPHHC 1550
PG+ T C
Sbjct: 1229 PGYQATPDRQGC 1240
Score = 400 bits (1029), Expect = e-111
Identities = 296/918 (32%), Positives = 389/918 (42%), Gaps = 163/918 (17%)
Query: 503 CACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLD 562
C GF + +D+DEC+ +P CA G C N GSFRC C GF C D
Sbjct: 1791 CGNIPGFTFDIHTGKAVDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCED 1850
Query: 563 VDECHRVPPPCDLGR-CENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACK 621
+DEC C C N+PGS+ C C AG++ +P+GA C D +EC + P +C G C
Sbjct: 1851 IDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNGA-CVDRNECLEIPNVCSHGLCV 1909
Query: 622 NLPGSFRCVCPAGFRGSACEE---DVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRG 678
+L GS++C+C GF+ S + DVDEC E PCG G C NT GS++C C GF
Sbjct: 1910 DLQGSYQCICHNGFKASQDQTMCMDVDEC--ERHPCGNGTCKNTVGSYNCLCYPGFELTH 1967
Query: 679 PGAPCQDVDECARS-PPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLAC 737
C D+DEC+ C GRC N GSF+C+C G++ G C D +EC +A
Sbjct: 1968 NN-DCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNEC---VAL 2023
Query: 738 PGQ----ECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRC 793
PG C N GSF+C CP G+ + C D++EC C G CTNT G F+C
Sbjct: 2024 PGSCSPGTCQNLEGSFRC-ICPPGYEVKSENCIDINECDEDPNIC-LFGSCTNTPGGFQC 2081
Query: 794 SCAPGY-RAPSGRPGPCADVNECLEGDFCFPH---GECL------NTDGSFACTCAPGYR 843
C PG+ + +GR C D + FCF + G+C T C+ PG
Sbjct: 2082 LCPPGFVLSDNGRR--CFDTRQ----SFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEG 2135
Query: 844 PG------------------PRGASCL--------DVDECSEED-LCQSGICTNTDGSFE 876
G P G + DV+EC E +C +G C NTDGSF
Sbjct: 2136 WGDPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICSNGQCINTDGSFR 2195
Query: 877 CICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTC 936
C CP G+ C+D DEC P CG+ C N GS+ C +C+ G+ GP C
Sbjct: 2196 CECPMGYNLDYTGVRCVDTDECSIGNP--CGNGTCTNVIGSFEC--NCNEGFEPGPMMNC 2251
Query: 937 DDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGG-CQDVDECRNRSFCGAH 995
+D++EC + P +C A RC NT GSY CT C GY C+D+DEC G H
Sbjct: 2252 EDINECAQ-NPLLC-AFRCMNTFGSYECT--CPIGYALREDQKMCKDLDECAE----GLH 2303
Query: 996 ------AVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLC 1049
+C+NL G+F C+C G DG CVD NEC T G+C C N+ GS+ C
Sbjct: 2304 DCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRC 2363
Query: 1050 VC-------PNSPEEFDPMTGRCVPP---------RTSAGTFPGSQPQAPASPVLPARPP 1093
C + E D G C +S S+ +
Sbjct: 2364 ECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCE 2423
Query: 1094 PPPLPRRPSTPRQGPVGSGR----RECYFDTAAPDACDNILARNVTWQ-ECCCTVG---E 1145
PLP + P G G R+ P+ C N N C C VG +
Sbjct: 2424 LCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTD 2483
Query: 1146 GWGSGC----RIQQ--------CPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLF 1193
G+ C Q C TE YQ CP RGY+ D +D+DECQ
Sbjct: 2484 ISGTSCIDLDECSQSPKPCNYICKNTE-GSYQCSCP--RGYVLQE-DGKTCKDLDECQTK 2539
Query: 1194 RDQ------------VCK---------------------------SGVCVNTAPGYSCYC 1214
+ CK G+C NT +SC C
Sbjct: 2540 QHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPSLCGAKGICQNTPGSFSCEC 2599
Query: 1215 SNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNES 1274
G+ L C D DEC D C+ G C N +G Y C C + +CV
Sbjct: 2600 QRGFSLDATGLNCEDVDEC-DGNHRCQHG-CQNILGGYRCGCPQGYIQHYQWNQCVDENE 2657
Query: 1275 QSLDDNLG--VCWQEVGA 1290
S + G C+ +G+
Sbjct: 2658 CSNPNACGSASCYNTLGS 2675
Score = 348 bits (892), Expect = 3e-95
Identities = 267/824 (32%), Positives = 360/824 (43%), Gaps = 125/824 (15%)
Query: 277 CPTGFERV-NGSCEDVDECAT--GGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQH 333
C GFE N C D+DEC++ G C++G C N G + C+C +G+ L +CI +
Sbjct: 1959 CYPGFELTHNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTN 2018
Query: 334 VISEAKGPCFRVLRDGGCSLPILRNITKQI-CCCSRVGKAWGRGC----------QLCPP 382
V G CS +N+ C C + C +C
Sbjct: 2019 EC---------VALPGSCSPGTCQNLEGSFRCICPPGYEVKSENCIDINECDEDPNICL- 2068
Query: 383 FGS-----EGFREICPAGPGYHYSASDLR-YNTRPL--------GQ-EPPRVSLSQPRTL 427
FGS GF+ +CP PG+ S + R ++TR G+ P+ +
Sbjct: 2069 FGSCTNTPGGFQCLCP--PGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKC 2126
Query: 428 PATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAW---TGPEIPESGPSSGMCQR 484
+ P G+ L P+ + E+ + + T P + ++ C
Sbjct: 2127 CCSKMPGEGWGDPCELCPKDD---------EVAFQDLCPYGHGTVPSLHDTREDVNECLE 2177
Query: 485 NPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFR 544
+P +C G+CI+ + C C G+ L G RC+D DEC + PC G C N GSF
Sbjct: 2178 SPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDEC-SIGNPCGNGTCTNVIGSFE 2236
Query: 545 CVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQD 604
C C GF GP C D++EC + P C RC NT GS+ C CP GY C+D
Sbjct: 2237 CNCNEGFEPGP-MMNCEDINECAQNPLLCAF-RCMNTFGSYECTCPIGYALREDQKMCKD 2294
Query: 605 VDECTQSPGLC-GRG-ACKNLPGSFRCVCPAGFR----GSACEEDVDECAQEPPPCGPGR 658
+DEC + C RG CKNL G+F C+CP G G C D +EC +P C GR
Sbjct: 2295 LDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGC-VDENECRTKPGICENGR 2353
Query: 659 CDNTAGSFHCACPAGFRSRGPGAPCQDVDE---------------------CARSPPPCT 697
C N GS+ C C GF+S G C D + +S C
Sbjct: 2354 CVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCD 2413
Query: 698 YGR-----CE----NTEGSFQCVCPMGFQPNTAGSECEDVDECE-NHLACPGQECVNSPG 747
GR CE ++ +CP G T G D+DEC+ C +C+N+ G
Sbjct: 2414 GGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDG---RDIDECKVMPNLCTNGQCINTMG 2470
Query: 748 SFQCRTCPSGH--HLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGY-RAPSG 804
SF+C C G+ + C D+DECS PC + C NTEGS++CSC GY G
Sbjct: 2471 SFRC-FCKVGYTTDISGTSCIDLDECSQSPKPC--NYICKNTEGSYQCSCPRGYVLQEDG 2527
Query: 805 RPGPCADVNEC-LEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDEC-SEEDL 862
+ C D++EC + C C+NT G F C C PG+ +C+D +EC S+ L
Sbjct: 2528 K--TCKDLDECQTKQHNC--QFLCVNTLGGFTCKCPPGFT--QHHTACIDNNECGSQPSL 2581
Query: 863 C-QSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCV 921
C GIC NT GSF C C G +C DVDEC G C C+N G YRC
Sbjct: 2582 CGAKGICQNTPGSFSCECQRGFSLDATGLNCEDVDEC--DGNHRC-QHGCQNILGGYRC- 2637
Query: 922 RDCDPGYHAGPE-GTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQ-PTPGGG 979
C GY + C D +EC P CG+ C NT GSY+C AC G+
Sbjct: 2638 -GCPQGYIQHYQWNQCVDENECS--NPNACGSASCYNTLGSYKC--ACPSGFSFDQFSSA 2692
Query: 980 CQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCV 1023
C DV+EC + S + C N G + C C GY G HCV
Sbjct: 2693 CHDVNEC-SSSKNPCNYGCSNTEGGYLCGCPPGYYRVGQG-HCV 2734
Score = 333 bits (855), Expect = 6e-91
Identities = 291/1006 (28%), Positives = 384/1006 (38%), Gaps = 194/1006 (19%)
Query: 482 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDV-----------DECRRVPPP 530
C P +C G C + Y C C G+ S G+RCID C + P
Sbjct: 322 CSIIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCFSGLVNGRCAQELPG 381
Query: 531 --------CAPGRC-------ENSP--GS--FRCVCGPGFRAG--PRAAECLDVDECHRV 569
C PGRC E P GS +R +C G G P +A
Sbjct: 382 RMTKMQCCCEPGRCWGIGTIPEACPVRGSEEYRRLCMDGLPMGGIPGSAGSRPGGTGGNG 441
Query: 570 PPPCDLGRCENTPGSFLCVCPAGYQAAPH--GASC----------------QDVDECTQS 611
P G G+ P G +P GA Q +D C
Sbjct: 442 FAPSGNGNGYGPGGTGFIPIPGGNGFSPGVGGAGVGAGGQGPIITGLTILNQTIDICKHH 501
Query: 612 PGLCGRGACKNLPGSFRCVCPAGFRGSACEE--DVDECAQEPPPCGPGRCDNTAGSFHCA 669
LC G C S+RC C G++ A + DVDEC P C G C NT GS++C
Sbjct: 502 ANLCLNGRCIPTVSSYRCECNMGYKQDANGDCIDVDECTSNP--CTNGDCVNTPGSYYCK 559
Query: 670 CPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVD 729
C AGF+ C D+DEC ++ C GRC NT+GSFQC+C GF+ T G C D D
Sbjct: 560 CHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQCICNAGFELTTDGKNCVDHD 619
Query: 730 ECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGR-CTDVDECSSGAPPCGPHGHCTNTE 788
EC C C+N GSF+C P GR CTDVDEC + P +GHC N+E
Sbjct: 620 ECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTDVDECQT--PGICMNGHCINSE 677
Query: 789 GSFRCSCAPGYRAPSGRPGP-CADVN---ECLEG---DFC---FPHGE------CLNTDG 832
GSFRC C PG G G C D + C G C FP C N D
Sbjct: 678 GSFRCDCPPGLAV--GMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDY 735
Query: 833 SFACTCAPGYRPGPRGASC--------------LDVDECS-EEDLCQSGICTNTDGSFEC 877
F C P P A D++EC+ + D+C +GIC N GS+ C
Sbjct: 736 GFGEPCQPC--PAKNSAEFHGLCSSGVGITVDGRDINECALDPDICANGICENLRGSYRC 793
Query: 878 ICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEG-TC 936
C G+ +C+D+DEC LC + C N+PGSY C C PGY E TC
Sbjct: 794 NCNSGYEPDASGRNCIDIDECLVNR-LLCDNGLCRNTPGSYSCT--CPPGYVFRTETETC 850
Query: 937 DDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGG------------------ 978
+D++EC E P + GA C N GS+ C C PG + + G
Sbjct: 851 EDINEC-ESNPCVNGA--CRNNLGSFNCE--CSPGSKLSSTGLICIDSLKGTCWLNIQDS 905
Query: 979 -------GCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETL 1031
G EC + C+ C +G + G C DVNECE
Sbjct: 906 RCEVNINGATLKSECCATLGAAWGSPCERC--ELDTACPRGLARIK-GVTCEDVNECEVF 962
Query: 1032 QGVCGAALCENVEGSFLCVCP------------------------NSPEEFDPMTGRCVP 1067
GVC C N +GSF C CP + E P+ G+
Sbjct: 963 PGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPVPGKFRM 1022
Query: 1068 PRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGR------RECYFDTA 1121
+ P + PR +G V +GR EC A
Sbjct: 1023 DACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINEC---KA 1079
Query: 1122 APDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQ-SLCPHGRGYLAP--- 1177
P C RN T C G+ + C + LC G P
Sbjct: 1080 FPGMCTYGKCRN-TIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSF 1138
Query: 1178 ---------SGDLSLRR--DVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLE 1226
SG + ++ D+DEC+ +C+ G CVNT + C C G+ R +
Sbjct: 1139 ECECFEGYESGFMMMKNCMDIDECER-NPLLCRGGTCVNTEGSFQCDCPLGHELSPSRED 1197
Query: 1227 CIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQ 1286
C+D +EC+ + C G+CVN +G+Y C+C P ++ C + + +
Sbjct: 1198 CVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNG------ 1251
Query: 1287 EVGADLVCSHPRLDRQATYTECCCLYGEAWGMDCALCPAQDSDDFE 1332
G D C+ + + +Y EC C G A D C D D+ E
Sbjct: 1252 --GCDTQCT----NSEGSY-ECSCSEGYALMPDGRSC--ADIDECE 1288
Score = 310 bits (795), Expect = 5e-84
Identities = 184/517 (35%), Positives = 244/517 (47%), Gaps = 59/517 (11%)
Query: 482 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPG--RCENS 539
C +NP +C RC++ Y C C G+ L C D+DEC C C+N
Sbjct: 2257 CAQNPLLCA-FRCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNL 2315
Query: 540 PGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHG 599
G+F C+C PG P C+D +EC P C+ GRC N GS+ C C G+Q++ G
Sbjct: 2316 IGTFMCICPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSG 2375
Query: 600 ASCQDVDE---------------------CTQSPGLC--GRG---ACK--NLPGS--FRC 629
C D + T+S C GRG C+ LPG+ ++
Sbjct: 2376 TECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKK 2435
Query: 630 VCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDEC 689
+CP G + D+DEC P C G+C NT GSF C C G+ + G C D+DEC
Sbjct: 2436 ICPHGPGYTTDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDEC 2495
Query: 690 ARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSF 749
++SP PC Y C+NTEGS+QC CP G+ G C+D+DEC+ CVN+ G F
Sbjct: 2496 SQSPKPCNY-ICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGF 2554
Query: 750 QCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPC 809
C+ CP G H C D +EC S CG G C NT GSF C C G+ + C
Sbjct: 2555 TCK-CPPGFTQHHTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLN-C 2612
Query: 810 ADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICT 869
DV+EC +G+ HG C N G + C C GY + C+D +ECS + C S C
Sbjct: 2613 EDVDEC-DGNHRCQHG-CQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNACGSASCY 2670
Query: 870 NTDGSFECICPPGHRAGPDLASCLDVDEC-RERGPALCGSQRCENSPGSYRCVRDCDPGY 928
NT GS++C CP G ++C DV+EC + P G C N+ G Y C C PGY
Sbjct: 2671 NTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNPCNYG---CSNTEGGYLC--GCPPGY 2725
Query: 929 HAGPEGTC---------------DDVDECQEYGPEIC 950
+ +G C +VDE PE C
Sbjct: 2726 YRVGQGHCVSGMGFNKGQYLSLDTEVDEENALSPEAC 2762
Score = 301 bits (772), Expect = 2e-81
Identities = 289/1040 (27%), Positives = 386/1040 (37%), Gaps = 293/1040 (28%)
Query: 444 EPRPEPRPDPRPGP------ELPLPSIPAWTGPEIPESGP--SSGMCQRNPQ--VCGPGR 493
+P+P P PRP P S + PE E G +S + +R Q + GP
Sbjct: 29 QPQPPPPKPPRPQPPPQQVRSATAGSEGGFLAPEYREEGAAVASRVRRRGQQDVLRGPNV 88
Query: 494 CISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRA 553
C SR Y C G++ P G +CI VP C NS CG GF +
Sbjct: 89 CGSRFHSYCC---PGWKTLPGGNQCI-------VP------ICRNS-------CGDGFCS 125
Query: 554 GPRAAECLDVDECHRVPPPCDLGRCENTPGS-FLCVCPAGYQAAPHGASCQDVDECTQSP 612
P C G+ +T GS + C +G +C D D C
Sbjct: 126 RPNMC-------------TCSSGQISSTCGSKSIQQCSV---RCMNGGTCAD-DHCQCQK 168
Query: 613 G----LCGRGACKN-------LPGSFRCVCPAGFRGSACEED------------------ 643
G CG+ C+N G RC C GF G CE D
Sbjct: 169 GYIGTYCGQPVCENGCQNGGRCIGPNRCACVYGFTGPQCERDYRTGPCFTQVNNQMCQGQ 228
Query: 644 ----------------------VDECAQEPPPC--------------------------G 655
+ C +P PC
Sbjct: 229 LTGIVCTKTLCCATIGRAWGHPCEMCPAQPQPCRRGFIPNIRTGACQDVDECQAIPGICQ 288
Query: 656 PGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMG 715
G C NT GSF C CPAG + C+D+DEC+ P C G C NT GS+ CVCP G
Sbjct: 289 GGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETGECSNTVGSYFCVCPRG 348
Query: 716 FQPNTAGSECED--VDECENHLA-------CPGQ----ECVNSPGSFQC-------RTCP 755
+ +T GS C D C + L PG+ +C PG +C CP
Sbjct: 349 YVTSTDGSRCIDQRTGMCFSGLVNGRCAQELPGRMTKMQCCCEPG--RCWGIGTIPEACP 406
Query: 756 -SGHHLHRGRCTDVDEC-----SSGAPPCGPHGHCTNTEGSFR---------------CS 794
G +R C D S+G+ P G G+ G+
Sbjct: 407 VRGSEEYRRLCMDGLPMGGIPGSAGSRPGGTGGNGFAPSGNGNGYGPGGTGFIPIPGGNG 466
Query: 795 CAPGYRAP---SGRPGPCAD----VNECLEGDFCFPH------GECLNTDGSFACTCAPG 841
+PG +G GP +N+ + D C H G C+ T S+ C C G
Sbjct: 467 FSPGVGGAGVGAGGQGPIITGLTILNQTI--DICKHHANLCLNGRCIPTVSSYRCECNMG 524
Query: 842 YRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRER 901
Y+ G C+DVDEC+ C +G C NT GS+ C C G + P +C+D+DEC +
Sbjct: 525 YKQDANG-DCIDVDECTSNP-CTNGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQN 582
Query: 902 GPALCGSQRCENSPGSYRCVRDCDPGYHAGPEG-TCDDVDECQEYGPEICGAQRCENTPG 960
G LC + RC N+ GS++C+ C+ G+ +G C D DEC +C C N G
Sbjct: 583 G-VLCKNGRCVNTDGSFQCI--CNAGFELTTDGKNCVDHDECTT--TNMCLNGMCINEDG 637
Query: 961 SYRCTPACDPGYQPTPGGG-CQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDG 1019
S++C C PG+ P G C DVDEC+ C + C N GSF+C C G DG
Sbjct: 638 SFKC--ICKPGFVLAPNGRYCTDVDECQTPGIC-MNGHCINSEGSFRCDCPPGLAVGMDG 694
Query: 1020 RHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQ 1079
R CVD + ++ C + + V CV P FPG+
Sbjct: 695 RVCVDTH----MRSTCYGGIKKGV---------------------CVRP------FPGAV 723
Query: 1080 PQAP---ASPVLPARPPPPPLPRRPSTPRQGPVGSG---------RRECYFDTAAPDACD 1127
++ A+P P P P + S G SG EC D PD C
Sbjct: 724 TKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGRDINECALD---PDICA 780
Query: 1128 NILARNVTWQ-ECCCTVG---EGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSL 1183
N + N+ C C G + G C
Sbjct: 781 NGICENLRGSYRCNCNSGYEPDASGRNC-------------------------------- 808
Query: 1184 RRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGG 1243
D+DEC L +C +G+C NT YSC C GY + T+ C D +EC E C G
Sbjct: 809 -IDIDEC-LVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINEC--ESNPCVNG 864
Query: 1244 RCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRLDRQA 1303
C N +GS++C C P L + C+ D G CW + D C ++
Sbjct: 865 ACRNNLGSFNCECSPGSKLSSTGLICI-------DSLKGTCWLNI-QDSRC-EVNINGAT 915
Query: 1304 TYTECCCLYGEAWGMDCALC 1323
+ECC G AWG C C
Sbjct: 916 LKSECCATLGAAWGSPCERC 935
Score = 235 bits (599), Expect = 3e-61
Identities = 168/516 (32%), Positives = 230/516 (44%), Gaps = 79/516 (15%)
Query: 222 CFRELRGGECASPLP-GLRTQEVCCRGAG-LAWGVHDCQ----LCSERLGNSERVSAPDG 275
C EC P+ LR + C+ A G+HDC+ +C +G +
Sbjct: 2268 CMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCI----- 2322
Query: 276 PCPTGFERV--NGSCEDVDECATG-GRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQ 332
CP G R C D +EC T G C++G C N G Y C C +GF SS + C+
Sbjct: 2323 -CPPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDN 2381
Query: 333 HVISEAKGPCFRVLRDGGCSLPIL-RN-ITKQICCCSRVGKAWGRGCQLCPPFGSEGFRE 390
+G CF + C + RN +TK CCC G+ WG C+LCP G+ +++
Sbjct: 2382 R-----QGLCFAEVLQTICQMASSSRNLVTKSECCCDG-GRGWGHQCELCPLPGTAQYKK 2435
Query: 391 ICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLP--ATSRPSAGFLPTHRLEPRPE 448
ICP GPGY D + + + +P T+ + + R +
Sbjct: 2436 ICPHGPGYTTDGRD----------------IDECKVMPNLCTNGQCINTMGSFRCFCKVG 2479
Query: 449 PRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQ---RNPQVCGPGRCISRPSGYTCAC 505
D I + ++ E S C +N + G +C S P GY
Sbjct: 2480 YTTD-----------ISGTSCIDLDECSQSPKPCNYICKNTE--GSYQC-SCPRGYV--- 2522
Query: 506 DSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDE 565
L G C D+DEC+ C C N+ G F C C PGF A C+D +E
Sbjct: 2523 -----LQEDGKTCKDLDECQTKQHNC-QFLCVNTLGGFTCKCPPGFTQHHTA--CIDNNE 2574
Query: 566 CHRVPPPCDL-GRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLP 624
C P C G C+NTPGSF C C G+ G +C+DVDEC C G C+N+
Sbjct: 2575 CGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNCEDVDEC-DGNHRCQHG-CQNIL 2632
Query: 625 GSFRCVCPAG----FRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPG 680
G +RC CP G ++ + C D +EC+ P CG C NT GS+ CACP+GF
Sbjct: 2633 GGYRCGCPQGYIQHYQWNQC-VDENECS-NPNACGSASCYNTLGSYKCACPSGFSFDQFS 2690
Query: 681 APCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGF 716
+ C DV+EC+ S PC YG C NTEG + C CP G+
Sbjct: 2691 SACHDVNECSSSKNPCNYG-CSNTEGGYLCGCPPGY 2725
Score = 129 bits (324), Expect = 2e-29
Identities = 108/389 (27%), Positives = 152/389 (39%), Gaps = 50/389 (12%)
Query: 220 GYCFRELRGGEC--ASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPC 277
G CF E+ C AS L T+ CC G WG H C+LC + P GP
Sbjct: 2384 GLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWG-HQCELCPLPGTAQYKKICPHGPG 2442
Query: 278 PTGFERVNGSCEDVDECAT-GGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVIS 336
T R D+DEC C +G+C NT G + C C G+ D S +SCI S
Sbjct: 2443 YTTDGR------DIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECS 2496
Query: 337 EAKGPCFRVLRDG----GCSLPILRNITKQICCCSRVGKAWGR--GCQLCPPFGSEGFRE 390
++ PC + ++ CS P + + C + + + CQ GF
Sbjct: 2497 QSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTC 2556
Query: 391 ICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPR 450
CP G H++A + G +P SL + + + P + R
Sbjct: 2557 KCPPGFTQHHTAC---IDNNECGSQP---SLCGAKGI-CQNTPGSFSCECQR-------- 2601
Query: 451 PDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFR 510
G L + E + + CQ C + GY C C G+
Sbjct: 2602 -----GFSLDATGLNC----EDVDECDGNHRCQHG--------CQNILGGYRCGCPQGYI 2644
Query: 511 LSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVP 570
Q +C+D +EC P C C N+ GS++C C GF ++ C DV+EC
Sbjct: 2645 QHYQWNQCVDENECSN-PNACGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSK 2703
Query: 571 PPCDLGRCENTPGSFLCVCPAGYQAAPHG 599
PC+ G C NT G +LC CP GY G
Sbjct: 2704 NPCNYG-CSNTEGGYLCGCPPGYYRVGQG 2731
Score = 65.9 bits (159), Expect = 3e-10
Identities = 30/93 (32%), Positives = 44/93 (47%), Gaps = 4/93 (4%)
Query: 1465 LEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1524
++ +EC + C NG C+ F C C G+ L C D++EC +C+N
Sbjct: 616 VDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTDVDECQ----TPGICMNG 671
Query: 1525 RCLNTDGSFRCICRPGFAPTHQPHHCAPARPRA 1557
C+N++GSFRC C PG A C R+
Sbjct: 672 HCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRS 704
Score = 65.5 bits (158), Expect = 4e-10
Identities = 33/91 (36%), Positives = 44/91 (48%), Gaps = 6/91 (6%)
Query: 1465 LEAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 1523
++ EC L G C+ G C + F C C GY + C+DINECDE +C+
Sbjct: 2015 IDTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSEN--CIDINECDEDPN---ICLF 2069
Query: 1524 ARCLNTDGSFRCICRPGFAPTHQPHHCAPAR 1554
C NT G F+C+C PGF + C R
Sbjct: 2070 GSCTNTPGGFQCLCPPGFVLSDNGRRCFDTR 2100
Score = 64.7 bits (156), Expect = 7e-10
Identities = 28/77 (36%), Positives = 45/77 (58%), Gaps = 5/77 (6%)
Query: 1466 EAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1524
+ +EC ++ CTNG+C+ F C C GY D++ +C+D++EC + SP N
Sbjct: 2449 DIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQ----SPKPCNY 2504
Query: 1525 RCLNTDGSFRCICRPGF 1541
C NT+GS++C C G+
Sbjct: 2505 ICKNTEGSYQCSCPRGY 2521
Score = 63.9 bits (154), Expect = 1e-09
Identities = 35/91 (38%), Positives = 47/91 (51%), Gaps = 12/91 (13%)
Query: 1466 EAEECGIL-DGCTNGRCVRVPEGFTCRCFDGYRLDMTRMA-CVDINECDEAEAASPLCVN 1523
+ +EC I D C +G CV P F C CF+GY M C+DI+EC+ LC
Sbjct: 1115 DIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPL---LCRG 1171
Query: 1524 ARCLNTDGSFRCICRPGFAPTHQPHHCAPAR 1554
C+NT+GSF+C C G H +P+R
Sbjct: 1172 GTCVNTEGSFQCDCPLG-------HELSPSR 1195
Score = 59.3 bits (142), Expect = 3e-08
Identities = 28/90 (31%), Positives = 40/90 (44%), Gaps = 4/90 (4%)
Query: 1466 EAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1524
+ +EC + G C G C+ F CRC G++ T C DI+EC +C
Sbjct: 276 DVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCEDIDEC---SIIPGICETG 332
Query: 1525 RCLNTDGSFRCICRPGFAPTHQPHHCAPAR 1554
C NT GS+ C+C G+ + C R
Sbjct: 333 ECSNTVGSYFCVCPRGYVTSTDGSRCIDQR 362
Score = 59.3 bits (142), Expect = 3e-08
Identities = 28/88 (31%), Positives = 42/88 (47%), Gaps = 5/88 (5%)
Query: 1465 LEAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 1523
++ EC + D C NG+CV + + C C GY+ R C DI+EC +
Sbjct: 1199 VDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGG----CD 1254
Query: 1524 ARCLNTDGSFRCICRPGFAPTHQPHHCA 1551
+C N++GS+ C C G+A CA
Sbjct: 1255 TQCTNSEGSYECSCSEGYALMPDGRSCA 1282
Score = 59.3 bits (142), Expect = 3e-08
Identities = 31/90 (34%), Positives = 41/90 (45%), Gaps = 4/90 (4%)
Query: 1466 EAEECGILDG-CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1524
+ +EC L G C G C+ F C C GY L C DI+EC A +C
Sbjct: 1650 DIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDEC---FAHPGVCGPG 1706
Query: 1525 RCLNTDGSFRCICRPGFAPTHQPHHCAPAR 1554
C NT G++ CIC P + + H+C R
Sbjct: 1707 TCYNTLGNYTCICPPEYMQVNGGHNCMDMR 1736
Score = 54.7 bits (130), Expect = 7e-07
Identities = 26/84 (30%), Positives = 38/84 (45%), Gaps = 4/84 (4%)
Query: 1465 LEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1524
++ EC + C + C + C C G+ D AC D+NEC ++S N
Sbjct: 2653 VDENECSNPNACGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNEC----SSSKNPCNY 2708
Query: 1525 RCLNTDGSFRCICRPGFAPTHQPH 1548
C NT+G + C C PG+ Q H
Sbjct: 2709 GCSNTEGGYLCGCPPGYYRVGQGH 2732
Score = 54.3 bits (129), Expect = 9e-07
Identities = 71/269 (26%), Positives = 96/269 (35%), Gaps = 61/269 (22%)
Query: 1079 QPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQE 1138
QPQ P P P RP PPP R +T G G Y + A A + R Q+
Sbjct: 29 QPQPP--PPKPPRPQPPPQQVRSAT--AGSEGGFLAPEYREEGAAVA-SRVRRRG---QQ 80
Query: 1139 CCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVC 1198
GS CPG +T P G + P C+ C
Sbjct: 81 DVLRGPNVCGSRFHSYCCPGWKT------LPGGNQCIVPI-----------CR----NSC 119
Query: 1199 KSGVCVNTAPGYSCYCSNGYYYHT--------QRLECIDNDECADEEPACEGGRCVNTVG 1250
G C + P C CS+G T + C++ CAD+ C+ G +G
Sbjct: 120 GDGFC--SRPN-MCTCSSGQISSTCGSKSIQQCSVRCMNGGTCADDHCQCQKG----YIG 172
Query: 1251 SYHCTCEPPLVLDGSQR--RCV-----------SNESQSLDDNLGVCWQEVGADLVCSHP 1297
+Y C P+ +G Q RC+ + D G C+ +V + +C
Sbjct: 173 TY---CGQPVCENGCQNGGRCIGPNRCACVYGFTGPQCERDYRTGPCFTQVN-NQMCQGQ 228
Query: 1298 RLDRQATYTECCCLYGEAWGMDCALCPAQ 1326
T T CC G AWG C +CPAQ
Sbjct: 229 LTGIVCTKTLCCATIGRAWGHPCEMCPAQ 257
Score = 52.8 bits (125), Expect = 3e-06
Identities = 37/166 (22%), Positives = 67/166 (40%), Gaps = 21/166 (12%)
Query: 237 GLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPTGFERVNGSC--EDVDEC 294
G R CC G G + C + R + + C +++ +C + + +C
Sbjct: 90 GSRFHSYCCPGWKTLPGGNQCIVPICRNSCGDGFCSRPNMCTCSSGQISSTCGSKSIQQC 149
Query: 295 AT----GGRCQHGECANTRG--GYTC---VCPDGF-----LLDSSRSSCISQHVISEAK- 339
+ GG C C +G G C VC +G + +R +C+ + +
Sbjct: 150 SVRCMNGGTCADDHCQCQKGYIGTYCGQPVCENGCQNGGRCIGPNRCACVYGFTGPQCER 209
Query: 340 ----GPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCP 381
GPCF + + C + + + CC+ +G+AWG C++CP
Sbjct: 210 DYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAWGHPCEMCP 255
Score = 52.8 bits (125), Expect = 3e-06
Identities = 28/77 (36%), Positives = 37/77 (48%), Gaps = 5/77 (6%)
Query: 1466 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNAR 1525
+ +EC C +G C + G+ C C GY CVD NEC A C +A
Sbjct: 2614 DVDECDGNHRCQHG-CQNILGGYRCGCPQGYIQHYQWNQCVDENECSNPNA----CGSAS 2668
Query: 1526 CLNTDGSFRCICRPGFA 1542
C NT GS++C C GF+
Sbjct: 2669 CYNTLGSYKCACPSGFS 2685
Score = 52.4 bits (124), Expect = 3e-06
Identities = 28/88 (31%), Positives = 41/88 (46%), Gaps = 7/88 (7%)
Query: 1465 LEAEECGILDGC--TNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCV 1522
++ ECG G C P F+C C G+ LD T + C D++ECD + C
Sbjct: 2570 IDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECD----GNHRCQ 2625
Query: 1523 NARCLNTDGSFRCICRPGFAPTHQPHHC 1550
+ C N G +RC C G+ +Q + C
Sbjct: 2626 HG-CQNILGGYRCGCPQGYIQHYQWNQC 2652
Score = 48.9 bits (115), Expect = 4e-05
Identities = 35/113 (30%), Positives = 43/113 (38%), Gaps = 13/113 (11%)
Query: 1452 GSYAGSLAEPYEELEAEE-CGILDGCTNG---------RCVRVPEGFTCRCFDGYRLDMT 1501
GSY + Y E ++ C LD C G C + F C C G
Sbjct: 2273 GSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPD 2332
Query: 1502 RMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHCAPAR 1554
CVD NEC +C N RC+N GS+RC C GF + C R
Sbjct: 2333 GEGCVDENEC---RTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNR 2382
Score = 43.9 bits (102), Expect = 0.001
Identities = 29/99 (29%), Positives = 41/99 (41%), Gaps = 11/99 (11%)
Query: 1452 GSYAGSLAEPYEELEAEECGILDGCTNG------RCVRVPEGFTCRCFDGYRLDMTRMAC 1505
GS+ + E +E C ++ C RC+ + C C GY L + C
Sbjct: 2233 GSFECNCNEGFEPGPMMNCEDINECAQNPLLCAFRCMNTFGSYECTCPIGYALREDQKMC 2292
Query: 1506 VDINECDEA--EAASPLCVNARCLNTDGSFRCICRPGFA 1542
D++EC E + S C N G+F CIC PG A
Sbjct: 2293 KDLDECAEGLHDCESR---GMMCKNLIGTFMCICPPGMA 2328
Score = 42.4 bits (98), Expect = 0.004
Identities = 16/35 (45%), Positives = 22/35 (62%)
Query: 1507 DINECDEAEAASPLCVNARCLNTDGSFRCICRPGF 1541
D + DE + LC N +C+NT GSFRC C+ G+
Sbjct: 2446 DGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGY 2480
Score = 35.8 bits (81), Expect = 0.33
Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 14/74 (18%)
Query: 41 CGLRCVHGPTGSRCTPTCAPRNATSVDSGAPGGAAPGGPGFRAFLCPLICHNGGVCVKPD 100
C +RC++G T CA + G G P +C C NGG C+ P+
Sbjct: 149 CSVRCMNGGT-------CADDHCQCQKGYI--GTYCGQP-----VCENGCQNGGRCIGPN 194
Query: 101 RCLCPPDFAGKFCQ 114
RC C F G C+
Sbjct: 195 RCACVYGFTGPQCE 208
>gi|134244285 Notch homolog 3 [Homo sapiens]
Length = 2321
Score = 317 bits (812), Expect = 6e-86
Identities = 361/1179 (30%), Positives = 458/1179 (38%), Gaps = 279/1179 (23%)
Query: 481 MCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCI-DVDECRRVPPPCAP-GRCEN 538
+C NP GR I C C GF G C DVDEC PC GRC N
Sbjct: 365 ICDTNPV---NGRAI-------CTCPPGFT----GGACDQDVDECSIGANPCEHLGRCVN 410
Query: 539 SPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPC-DLGRCENTPGSFLCVCPAGYQAAP 597
+ GSF C CG G+ GPR DV+EC + PC + C + G F C+C AG+
Sbjct: 411 TQGSFLCQCGRGY-TGPRCET--DVNEC--LSGPCRNQATCLDRIGQFTCICMAGFT--- 462
Query: 598 HGASCQ-DVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGP 656
G C+ D+DEC SP + G G CK+ F C CP+GF GS C+ DVDECA P G
Sbjct: 463 -GTYCEVDIDECQSSPCVNG-GVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNG- 519
Query: 657 GRCDNTAGSFHCACPAGFRSRGPGAPC-QDVDECARSPPPCTYGRCENTEGSFQCVCPMG 715
+C + + C C GF G C ++VD+C SP PC +GRC + SF C C G
Sbjct: 520 AKCVDQPDGYECRCAEGFE----GTLCDRNVDDC--SPDPCHHGRCVDGIASFSCACAPG 573
Query: 716 FQPNTAGSECED-VDECENHLACPGQECVNSPGSFQCRTCPSG----------------- 757
+ G+ CE VDEC + G +C++ + CR CPSG
Sbjct: 574 Y----TGTRCESQVDECRSQPCRHGGKCLDLVDKYLCR-CPSGTTGVNCEVNIDDCASNP 628
Query: 758 -------HHLHRGRCT------------DVDECSSGAPPCGPHGHCTNTEGSFRCSCAPG 798
++R C +++EC+S PCG G C + E FRC C PG
Sbjct: 629 CTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASS--PCGEGGSCVDGENGFRCLCPPG 686
Query: 799 YRAPSGRPG--PCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDE 856
P P PCA C HG C + G F C C PG+ GPR + L D
Sbjct: 687 SLPPLCLPPSHPCAH-EPC-------SHGICYDAPGGFRCVCEPGWS-GPRCSQSLARDA 737
Query: 857 CSEEDLCQSGICTNTDGSFECICPPGHRAGP-DLASCLDVDECRERGPALCGSQRCENSP 915
C + G C++ F C CPPG + +L S + C G RCE++P
Sbjct: 738 CESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHGG-------RCESAP 790
Query: 916 GSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQR-CENTPGSYRCTPACDPGYQP 974
G V C G+ GP DVDEC GP CG C N GS+ CT C GY
Sbjct: 791 GQLP-VCSCPQGWQ-GPRCQ-QDVDECA--GPAPCGPHGICTNLAGSFSCT--CHGGYT- 842
Query: 975 TPGGGC-QDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQG 1033
G C QD+++C + + C CQ+ GSF C C G+ G R R DV+EC L
Sbjct: 843 --GPSCDQDINDC-DPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCAR---DVDEC--LSN 894
Query: 1034 VCGAALCENVEGSFLCVCPNSPEEF---------DPMT----GRCVPPRTSAGT-----F 1075
CG C + SF C CP F P + G CV S +
Sbjct: 895 PCGPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGY 954
Query: 1076 PGSQPQAPASPVLPARPP------PPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNI 1129
G+ Q A P L +RP P T + G + + D + C N
Sbjct: 955 TGAHCQHEADPCL-SRPCLHGGVCSAAHPGFRCTCLESFTGP-QCQTLVDWCSRQPCQNG 1012
Query: 1130 LARNVTWQECCCTVGEGW-GSGCRIQQCPGTETA-----EYQSLCPHG---------RGY 1174
T C C GW G C I+ P E A + LC G
Sbjct: 1013 GRCVQTGAYCLCP--PGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYC 1070
Query: 1175 LAPSGDLS--LRRDVDECQLFRDQVCK-SGVCVNTAPGYSCYCSNGYYYHTQRLECIDN- 1230
+ P G ++VD C Q C+ G C GY C C GY C D+
Sbjct: 1071 VCPEGRTGSHCEQEVDPCLA---QPCQHGGTCRGYMGGYMCECLPGYNGDN----CEDDV 1123
Query: 1231 DECADEEPACEGGRCVNTVGSYHCTCEPPLV----------------LDGSQRRCVSNES 1274
DECA + P GG C++ V Y C+C P + LD S RC+ N
Sbjct: 1124 DECASQ-PCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLD-SGPRCLHN-- 1179
Query: 1275 QSLDDNLGVCWQEVGADLVCSHPR----LDRQATYTEC----C-------CLYGEAWGMD 1319
G C VG C+ P L +A EC C CL G
Sbjct: 1180 -------GTCVDLVGG-FRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFR 1231
Query: 1320 CALCPAQDSDDFEALCNVLRPPAYSPP-----------RPGGFGLPYE-------YGP-- 1359
C LC A S C + P S P PGG GL + +GP
Sbjct: 1232 C-LCHAGFSGP---RCQTVLSPCESQPCQHGGQCRPSPGPGG-GLTFTCHCAQPFWGPRC 1286
Query: 1360 ------------DLGPPYQGLPYGPELYPPPALPYD-----PYPPPPGPFAR-------- 1394
+G P Q P GP PP L P PP A
Sbjct: 1287 ERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAAPCLH 1346
Query: 1395 ----REAPYGAPRFDMPDFEDDGGPYGESEAPAPP-GPGTRWPYRS----RDTRRSFPEP 1445
R AP AP F + GP E+ A AP R P + R +R E
Sbjct: 1347 GGSCRPAPL-APFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRCDREC 1405
Query: 1446 EEPP---EGGSYAGSLAEPYEELEAEECGILDGCTNGRC 1481
P +GG + S+ +P+ + EA +C L N RC
Sbjct: 1406 NSPGCGWDGGDCSLSVGDPWRQCEALQCWRL--FNNSRC 1442
Score = 305 bits (782), Expect = 2e-82
Identities = 307/1021 (30%), Positives = 395/1021 (38%), Gaps = 227/1021 (22%)
Query: 395 GPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEP-RPDP 453
GPG A R RP+ PP + L + P A P P R
Sbjct: 2 GPG----ARGRRRRRRPMSPPPPPPPVRALPLLLLLAGPGAAAPPCLDGSPCANGGRCTQ 57
Query: 454 RPGPELPLPSIPAWTGPEIP-----ESGPSSG--MCQ------------------RNPQV 488
P E P W G SGP +G +CQ R P
Sbjct: 58 LPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDC 117
Query: 489 CGPGRCISRPSG------------YTCACDSGFRLSPQGTRC-IDVDECRRVPPPCAPGR 535
P C+S P + C+C G+ QG C DVDECR P G
Sbjct: 118 SLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGY----QGRSCRSDVDECRVGEPCRHGGT 173
Query: 536 CENSPGSFRCVCGPGFRAGP----RAAECLDVDECHRVPPPCDLGRCENTPG--SFLCVC 589
C N+PGSFRC C G+ GP A C P PC G G ++ C C
Sbjct: 174 CLNTPGSFRCQCPAGY-TGPLCENPAVPC--------APSPCRNGGTCRQSGDLTYDCAC 224
Query: 590 PAGYQAAPHGASCQ-DVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECA 648
G++ G +C+ +VD+C L G G C + ++ C CP + G C EDVDEC
Sbjct: 225 LPGFE----GQNCEVNVDDCPGHRCLNG-GTCVDGVNTYNCQCPPEWTGQFCTEDVDECQ 279
Query: 649 QEPPPC-GPGRCDNTAGSFHCACPAGFRSRGPGAPC-QDVDECARSPPPCTYG-RCENTE 705
+P C G C NT G C C G+ G C Q++D+CA + C +G C +
Sbjct: 280 LQPNACHNGGTCFNTLGGHSCVCVNGW----TGESCSQNIDDCATA--VCFHGATCHDRV 333
Query: 706 GSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSP--GSFQCRTCPSGHHLHRG 763
SF C CPMG G C D C ++ C +P G C TCP G G
Sbjct: 334 ASFYCACPMG----KTGLLCHLDDACVSNPCHEDAICDTNPVNGRAIC-TCPPG--FTGG 386
Query: 764 RC-TDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCF 822
C DVDECS GA PC G C NT+GSF C C GY P DVNECL G C
Sbjct: 387 ACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCE----TDVNECLSGP-CR 441
Query: 823 PHGECLNTDGSFACTCAPGYRPGPRGASC-LDVDECSEEDLCQSGICTNTDGSFECICPP 881
CL+ G F C C G+ G C +D+DEC G+C + F C CP
Sbjct: 442 NQATCLDRIGQFTCICMAGF----TGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPS 497
Query: 882 GHRAGPDLASC-LDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGT-CD-D 938
G ++C LDVDEC P G+ +C + P Y C C G+ EGT CD +
Sbjct: 498 GFSG----STCQLDVDECAST-PCRNGA-KCVDQPDGYEC--RCAEGF----EGTLCDRN 545
Query: 939 VDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQ-DVDECRNRSFCGAHAV 997
VD+C P+ C RC + S+ C AC PGY G C+ VDECR++ C
Sbjct: 546 VDDC---SPDPCHHGRCVDGIASFSC--ACAPGY---TGTRCESQVDECRSQP-CRHGGK 596
Query: 998 CQNLPGSFQCLCDQGYEG-------------------ARDGRH---C------------V 1023
C +L + C C G G RDG + C V
Sbjct: 597 CLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNV 656
Query: 1024 DVNECETLQGVCG-AALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQA 1082
++NEC + CG C + E F C+CP P P+ C+PP P S
Sbjct: 657 EINECAS--SPCGEGGSCVDGENGFRCLCP--PGSLPPL---CLPPSHPCAHEPCSHGIC 709
Query: 1083 PASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCT 1142
+P G R C + P C LAR+ + C
Sbjct: 710 YDAP-----------------------GGFRCVCEPGWSGP-RCSQSLARDACESQPCRA 745
Query: 1143 VG----EGWGSGCRIQQCPGTETAEYQSL-------CPHGRGYLAPSGDLSL-------- 1183
G +G G C PG + + + L C HG + G L +
Sbjct: 746 GGTCSSDGMGFHCTCP--PGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQ 803
Query: 1184 ----RRDVDECQLFRDQVC-KSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEP 1238
++DVDEC C G+C N A +SC C GY C + D P
Sbjct: 804 GPRCQQDVDECA--GPAPCGPHGICTNLAGSFSCTCHGGY----TGPSCDQDINDCDPNP 857
Query: 1239 ACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDD--NLGVCWQEVGADLVCSH 1296
GG C + VGS+ C+C P + RC + + L + G C V A C+
Sbjct: 858 CLNGGSCQDGVGSFSCSCLPGF----AGPRCARDVDECLSNPCGPGTCTDHV-ASFTCTC 912
Query: 1297 P 1297
P
Sbjct: 913 P 913
Score = 268 bits (686), Expect = 2e-71
Identities = 336/1142 (29%), Positives = 451/1142 (39%), Gaps = 216/1142 (18%)
Query: 205 QSAPREDGYSDASGFGYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERL 264
QS+P +G G C + G C P G+ V +C R
Sbjct: 474 QSSPCVNG-------GVCKDRVNGFSCTCPSG--------FSGSTCQLDVDECASTPCRN 518
Query: 265 GNSERVSAPDG---PCPTGFERVNGSCE-DVDECATGGRCQHGECANTRGGYTCVCPDGF 320
G ++ V PDG C GFE C+ +VD+C+ C HG C + ++C C G+
Sbjct: 519 G-AKCVDQPDGYECRCAEGFEGT--LCDRNVDDCSPDP-CHHGRCVDGIASFSCACAPGY 574
Query: 321 LLDSSRSSCISQHVISEAKG-PCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQL 379
+ + C SQ + E + PC R GG L + + K +C C G C++
Sbjct: 575 ----TGTRCESQ--VDECRSQPC----RHGGKCLDL---VDKYLCRCP--SGTTGVNCEV 619
Query: 380 ----CP----PFG--SEGF-REICPAGPGYHYSASDLRYN---TRPLGQEPPRVS----- 420
C FG +G R C PG+ ++ N + P G+ V
Sbjct: 620 NIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGF 679
Query: 421 --LSQPRTLPATSRPSAGFLPTHRL--EPRPEPRPDPRPGPELPLPSIPAWTGPEIPESG 476
L P +LP P P+H EP PG P W+GP +S
Sbjct: 680 RCLCPPGSLPPLCLP-----PSHPCAHEPCSHGICYDAPG-GFRCVCEPGWSGPRCSQS- 732
Query: 477 PSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCA-PGR 535
+ C+ P G G C S G+ C C G QG +C + C P PC GR
Sbjct: 733 LARDACESQPCRAG-GTCSSDGMGFHCTCPPGV----QGRQCELLSPC--TPNPCEHGGR 785
Query: 536 CENSPGSFR-CVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQ 594
CE++PG C C G++ GPR + DVDEC P G C N GSF C C GY
Sbjct: 786 CESAPGQLPVCSCPQGWQ-GPRCQQ--DVDECAGPAPCGPHGICTNLAGSFSCTCHGGYT 842
Query: 595 AAPHGASC-QDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPP 653
G SC QD+++C +P L G G+C++ GSF C C GF G C DVDEC P
Sbjct: 843 ----GPSCDQDINDCDPNPCLNG-GSCQDGVGSFSCSCLPGFAGPRCARDVDECLSN--P 895
Query: 654 CGPGRCDNTAGSFHCACPAGFRSRGPGAPC-QDVDECARSPPPC-TYGRCENTEGSFQCV 711
CGPG C + SF C CP G+ G C QD+ +C SP C G C + SF C+
Sbjct: 896 CGPGTCTDHVASFTCTCPPGY----GGFHCEQDLPDC--SPSSCFNGGTCVDGVNSFSCL 949
Query: 712 CPMGFQPNTAGSECE-DVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRC-TDVD 769
C +P G+ C+ + D C + G C + F+C S +C T VD
Sbjct: 950 C----RPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLES---FTGPQCQTLVD 1002
Query: 770 ECSSGAPPCGPHGHCTNTEGSFRCSCAPGY--RAPSGRPGPC----ADVNECLEGDFCFP 823
CS PC G C T G++ C C PG+ R R PC A + LE C
Sbjct: 1003 WCS--RQPCQNGGRCVQT-GAY-CLCPPGWSGRLCDIRSLPCREAAAQIGVRLE-QLCQA 1057
Query: 824 HGECLNTDGSFACTCAPGYRPGPRGASC-LDVDECSEEDLCQSGICTNTDGSFECICPPG 882
G+C++ D S C C G G+ C +VD C + G C G + C C PG
Sbjct: 1058 GGQCVDEDSSHYCVCP----EGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPG 1113
Query: 883 HRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCD-DVDE 941
+ G + DVDEC + GS C + Y C C PG C+ + D+
Sbjct: 1114 YN-GDNCED--DVDECASQPCQHGGS--CIDLVARYLC--SCPPGTLG---VLCEINEDD 1163
Query: 942 C-----QEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQ-DVDECRNRSFCGAH 995
C + GP C + G +RCT C PGY G C+ D++ECR+ + AH
Sbjct: 1164 CGPGPPLDSGPRCLHNGTCVDLVGGFRCT--CPPGY---TGLRCEADINECRSGACHAAH 1218
Query: 996 A--VCQNLPGSFQCLCDQGYEGAR--------DGRHCVDVNECETLQGVCGAAL------ 1039
Q+ G F+CLC G+ G R + + C +C G G
Sbjct: 1219 TRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCA 1278
Query: 1040 -------CENVEGSFL-CVCP-NSPEEFDPMTGRCVPPRTSAG----TFPGSQPQA---- 1082
CE V S CP P + P RC P +G +FPGS P A
Sbjct: 1279 QPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNAS 1338
Query: 1083 -PASPVLPARP--PPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTW--- 1136
A+P L P P P QG G C AAP+ +
Sbjct: 1339 CAAAPCLHGGSCRPAPLAPFFRCACAQGWTGP---RCEAPAAAPEVSEEPRCPRAACQAK 1395
Query: 1137 ---QEC---CCTVGEGW-GSGCRI------QQCPGTETAEYQSLCPHGRGYLAPSGDLSL 1183
Q C C + G GW G C + +QC E + L + R A S L
Sbjct: 1396 RGDQRCDRECNSPGCGWDGGDCSLSVGDPWRQC---EALQCWRLFNNSRCDPACSSPACL 1452
Query: 1184 RRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYY-----YHTQRLEC-IDNDECADEE 1237
+ D R++ C P Y YC++ + EC D +CA E
Sbjct: 1453 YDNFDCHAGGRERTCN--------PVYEKYCADHFADGRCDQGCNTEECGWDGLDCASEV 1504
Query: 1238 PA 1239
PA
Sbjct: 1505 PA 1506
Score = 266 bits (680), Expect = 1e-70
Identities = 261/877 (29%), Positives = 347/877 (39%), Gaps = 167/877 (19%)
Query: 255 HDCQLCSERLGNSERVSAPDGPCPTGFERVNGSCE-DVDECATGGR-CQH-GECANTRGG 311
H+ +C N + CP GF G+C+ DVDEC+ G C+H G C NT+G
Sbjct: 361 HEDAICDTNPVNGRAICT----CPPGF--TGGACDQDVDECSIGANPCEHLGRCVNTQGS 414
Query: 312 YTCVCPDGFL---LDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSR 368
+ C C G+ ++ + C+S GPC R+ L + T IC
Sbjct: 415 FLCQCGRGYTGPRCETDVNECLS--------GPC----RNQATCLDRIGQFT-CICMAGF 461
Query: 369 VG---KAWGRGCQLCPPFGS-------EGFREICPAGPGYHYSASDLRYNTRPLGQEPPR 418
G + CQ P GF CP+G +S S + + P R
Sbjct: 462 TGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSG----FSGSTCQLDVDECASTPCR 517
Query: 419 ---VSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPG-------PELPLPSIPAWT 468
+ QP R + GF T + PDP P +T
Sbjct: 518 NGAKCVDQPDGYEC--RCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYT 575
Query: 469 GPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRC-IDVDECRRV 527
G C+ P G G+C+ Y C C SG G C +++D+C
Sbjct: 576 GTRCESQVDE---CRSQPCRHG-GKCLDLVDKYLCRCPSG----TTGVNCEVNIDDC--A 625
Query: 528 PPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPC-DLGRCENTPGSFL 586
PC G C + + CVC PGF GP ++++EC PC + G C + F
Sbjct: 626 SNPCTFGVCRDGINRYDCVCQPGF-TGPLCN--VEINEC--ASSPCGEGGSCVDGENGFR 680
Query: 587 CVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDE 646
C+CP G + C P C G C + PG FRCVC G+ G C + +
Sbjct: 681 CLCPPG---SLPPLCLPPSHPCAHEP--CSHGICYDAPGGFRCVCEPGWSGPRCSQSLAR 735
Query: 647 CAQEPPPC-GPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTY-GRCENT 704
A E PC G C + FHC CP G + G C+ + C +P PC + GRCE+
Sbjct: 736 DACESQPCRAGGTCSSDGMGFHCTCPPGVQ----GRQCELLSPC--TPNPCEHGGRCESA 789
Query: 705 EGSFQ-CVCPMGFQPNTAGSEC-EDVDECENHLAC-PGQECVNSPGSFQCRTCPSGHHLH 761
G C CP G+Q G C +DVDEC C P C N GSF C TC G +
Sbjct: 790 PGQLPVCSCPQGWQ----GPRCQQDVDECAGPAPCGPHGICTNLAGSFSC-TCHGG---Y 841
Query: 762 RGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCA-DVNECLEGDF 820
G D D PC G C + GSF CSC PG+ P CA DV+ECL
Sbjct: 842 TGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPR-----CARDVDECLSNP- 895
Query: 821 CFPHGECLNTDGSFACTCAPGYRPGPRGASC-LDVDECSEEDLCQSGICTNTDGSFECIC 879
C P G C + SF CTC PGY G C D+ +CS G C + SF C+C
Sbjct: 896 CGP-GTCTDHVASFTCTCPPGY----GGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLC 950
Query: 880 PPG-------HRAGPDLA-SCLDVDECRERGPAL-------------------CGSQRCE 912
PG H A P L+ CL C P C Q C+
Sbjct: 951 RPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQ 1010
Query: 913 NSPGSYRCVRD-----CDPGYHAGPEGTCDDVDE--CQEYGPEI-------CGA-QRCEN 957
N RCV+ C PG+ G D+ C+E +I C A +C +
Sbjct: 1011 NGG---RCVQTGAYCLCPPGW----SGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVD 1063
Query: 958 TPGSYRCTPACDPGYQPTPGGGC-QDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGA 1016
S+ C C G G C Q+VD C + C C+ G + C C GY
Sbjct: 1064 EDSSHYC--VCPEG---RTGSHCEQEVDPCLAQP-CQHGGTCRGYMGGYMCECLPGY--- 1114
Query: 1017 RDGRHCV-DVNECETLQGVCGAALCENVEGSFLCVCP 1052
+G +C DV+EC + G + C ++ +LC CP
Sbjct: 1115 -NGDNCEDDVDECASQPCQHGGS-CIDLVARYLCSCP 1149
Score = 245 bits (625), Expect = 3e-64
Identities = 304/1072 (28%), Positives = 399/1072 (37%), Gaps = 187/1072 (17%)
Query: 530 PCAPG-RCENSPG-SFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENT----PG 583
PCA G RC P C+C PG+ G R C D CH P G C+++
Sbjct: 48 PCANGGRCTQLPSREAACLCPPGW-VGER---CQLEDPCHS-GPCAGRGVCQSSVVAGTA 102
Query: 584 SFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGA-CKNLP-GSFRCVCPAGFRGSACE 641
F C CP G++ G C D C SP C GA C P G F C CP G++G +C
Sbjct: 103 RFSCRCPRGFR----GPDCSLPDPCLSSP--CAHGARCSVGPDGRFLCSCPPGYQGRSCR 156
Query: 642 EDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRS---RGPGAPCQDVDECARSPPPCTY 698
DVDEC P G C NT GSF C CPAG+ P PC +P PC
Sbjct: 157 SDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPC--------APSPCRN 208
Query: 699 GRCENTEG--SFQCVCPMGFQPNTAGSECE-DVDECENHLACPGQECVNSPGSFQCRTCP 755
G G ++ C C GF+ G CE +VD+C H G CV+ ++ C+ CP
Sbjct: 209 GGTCRQSGDLTYDCACLPGFE----GQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQ-CP 263
Query: 756 ---SGHHLHRGRCT-DVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCA- 810
+G CT DVDEC C G C NT G C C G+ S C+
Sbjct: 264 PEWTGQF-----CTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGES-----CSQ 313
Query: 811 DVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGIC-T 869
++++C CF C + SF C C G G C D C + IC T
Sbjct: 314 NIDDCATA-VCFHGATCHDRVASFYCACP----MGKTGLLCHLDDACVSNPCHEDAICDT 368
Query: 870 N-TDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGY 928
N +G C CPPG G A DVDEC RC N+ GS+ C C GY
Sbjct: 369 NPVNGRAICTCPPGFTGG---ACDQDVDECSIGANPCEHLGRCVNTQGSFLC--QCGRGY 423
Query: 929 HAGPEGTCD-DVDECQEYGPEICGAQ-RCENTPGSYRCTPACDPGYQPTPGGGCQ-DVDE 985
GP C+ DV+EC GP C Q C + G + C C G+ G C+ D+DE
Sbjct: 424 -TGPR--CETDVNECLS-GP--CRNQATCLDRIGQFTC--ICMAGF---TGTYCEVDIDE 472
Query: 986 CRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHC-VDVNECETLQGVCGAAL----- 1039
C++ S C VC++ F C C G+ G+ C +DV+EC + GA
Sbjct: 473 CQS-SPCVNGGVCKDRVNGFSCTCPSGFSGST----CQLDVDECASTPCRNGAKCVDQPD 527
Query: 1040 ---CENVEGSFLCVCPNSPEEFDP---MTGRCVP--PRTSAGTFPGSQPQAPASPVLPAR 1091
C EG +C + ++ P GRCV S PG S V R
Sbjct: 528 GYECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECR 587
Query: 1092 PPP------------PPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARN-VTWQE 1138
P L R PS G G E D A + C + R+ + +
Sbjct: 588 SQPCRHGGKCLDLVDKYLCRCPS----GTTGV-NCEVNIDDCASNPCTFGVCRDGINRYD 642
Query: 1139 CCCTVG-EGWGSGCRIQQCPGTETAEYQSLCPHGRGY--LAPSGDLSLRRDVDECQLFRD 1195
C C G G I +C + E S G+ L P G L +
Sbjct: 643 CVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLP-PLCLPPSHPCAH 701
Query: 1196 QVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCT 1255
+ C G+C + G+ C C G + + + + D C + +P GG C + +HCT
Sbjct: 702 EPCSHGICYDAPGGFRCVCEPG-WSGPRCSQSLARDAC-ESQPCRAGGTCSSDGMGFHCT 759
Query: 1256 CEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLYGEA 1315
C P + G Q +S + + ++ G C G VCS P +
Sbjct: 760 CPPG--VQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCP----------------QG 801
Query: 1316 W-GMDCALCPAQDSDDFEALCNVLRPPAYSPPRPGGFGLPYEYGPDLGPPYQGLPYGPEL 1374
W G C QD D+ + P P G P+ +L + +G
Sbjct: 802 WQGPRC----QQDVDE------------CAGPAPCG---PHGICTNLAGSFSCTCHGG-- 840
Query: 1375 YPPPALPYDPYPPPPGPFAR-REAPYGAPRFDMPDFEDDGGPYGESEAPA----PPGPGT 1429
Y P+ D P P G F GP + P GPGT
Sbjct: 841 YTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGT 900
Query: 1430 RWPYRSRDTRRSFPEPEEPPEGGSYAGSLAEPYEELEAEECGILDGCTNGRCVRVPEGFT 1489
D SF P GG + E + +C G CV F+
Sbjct: 901 -----CTDHVASFTCTCPPGYGGFHC--------EQDLPDCSPSSCFNGGTCVDGVNSFS 947
Query: 1490 CRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGF 1541
C C GY T C +E D + P C FRC C F
Sbjct: 948 CLCRPGY----TGAHCQ--HEADPC-LSRPCLHGGVCSAAHPGFRCTCLESF 992
Score = 224 bits (572), Expect = 4e-58
Identities = 286/1063 (26%), Positives = 382/1063 (35%), Gaps = 250/1063 (23%)
Query: 608 CTQSPGLCGRGACKNLPG-SFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNT--AG 664
C G C LP C+CP G+ G C+ + D C P G G C ++ AG
Sbjct: 43 CLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQLE-DPC-HSGPCAGRGVCQSSVVAG 100
Query: 665 S--FHCACPAGFRSRGPGAPCQDVDECARSPPPCTYG-RCE-NTEGSFQCVCPMGFQPNT 720
+ F C CP GFR G C D C SP C +G RC +G F C CP G+Q +
Sbjct: 101 TARFSCRCPRGFR----GPDCSLPDPCLSSP--CAHGARCSVGPDGRFLCSCPPGYQGRS 154
Query: 721 AGSECEDVDECENHLACP-GQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCG 779
S DVDEC C G C+N+PGSF+C+ CP+G+ C + A PC
Sbjct: 155 CRS---DVDECRVGEPCRHGGTCLNTPGSFRCQ-CPAGY--------TGPLCENPAVPCA 202
Query: 780 PH-----GHCTNT-EGSFRCSCAPGYRA----------PSGR---PGPCAD--------- 811
P G C + + ++ C+C PG+ P R G C D
Sbjct: 203 PSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQC 262
Query: 812 ------------VNEC-LEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCL-DVDEC 857
V+EC L+ + C G C NT G +C C G+ G SC ++D+C
Sbjct: 263 PPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWT----GESCSQNIDDC 318
Query: 858 SEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQR-CENSPG 916
+ C + SF C CP G L LD D C C C+ +P
Sbjct: 319 ATAVCFHGATCHDRVASFYCACPMGKTG---LLCHLD-DACVSNP---CHEDAICDTNPV 371
Query: 917 SYRCVRDCDPGYHAGPEGTCD-DVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPT 975
+ R + C PG+ G CD DVDEC RC NT GS+ C C GY
Sbjct: 372 NGRAICTCPPGFTGG---ACDQDVDECSIGANPCEHLGRCVNTQGSFLCQ--CGRGYT-- 424
Query: 976 PGGGCQ-DVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHC-VDVNECETLQG 1033
G C+ DV+EC + C A C + G F C+C G+ G +C VD++EC++
Sbjct: 425 -GPRCETDVNECLSGP-CRNQATCLDRIGQFTCICMAGFTGT----YCEVDIDECQSSPC 478
Query: 1034 VCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVL--PAR 1091
V G + V G F C CP+ F GS Q P R
Sbjct: 479 VNGGVCKDRVNG-FSCTCPSG--------------------FSGSTCQLDVDECASTPCR 517
Query: 1092 PPPPPLPRRPSTPRQGPVGSGRREC--YFDTAAPDACDN-ILARNVTWQECCCTVG---- 1144
+ + + G C D +PD C + + C C G
Sbjct: 518 NGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGT 577
Query: 1145 --EGWGSGCRIQQCPGTETA-----EYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQV 1197
E CR Q C +Y CP G + ++ ++D+C
Sbjct: 578 RCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSG------TTGVNCEVNIDDCA---SNP 628
Query: 1198 CKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCE 1257
C GVC + Y C C G+ T L ++ +ECA P EGG CV+ + C C
Sbjct: 629 CTFGVCRDGINRYDCVCQPGF---TGPLCNVEINECASS-PCGEGGSCVDGENGFRCLCP 684
Query: 1258 P----PLVLDGSQRRCVSNESQSLDDNLGVCWQEVGA-DLVC----SHPR----LDRQAT 1304
P PL L S C G+C+ G VC S PR L R A
Sbjct: 685 PGSLPPLCLPPSHP-CAHEPCSH-----GICYDAPGGFRCVCEPGWSGPRCSQSLARDAC 738
Query: 1305 YTECCCLYG----EAWGMDCALCPAQDSDDFEALCNVLRPPAYSPPRPGGFGLPYEYGPD 1360
++ C G + G C P C +L P +P GG
Sbjct: 739 ESQPCRAGGTCSSDGMGFHCTCPPGVQGRQ----CELLSPCTPNPCEHGG---------- 784
Query: 1361 LGPPYQGLPYGPELYPPPALPYDPYPPPPGPFARREAPYGAPRFDMPDFEDDGGPYGESE 1420
PG P G + P + D E
Sbjct: 785 -----------------------RCESAPGQLPVCSCPQG---WQGPRCQQD---VDECA 815
Query: 1421 APAPPGP-----------------GTRWPYRSRDTRRSFPEP----EEPPEG-GSYAGS- 1457
PAP GP G P +D P P +G GS++ S
Sbjct: 816 GPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSC 875
Query: 1458 ---LAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEA 1514
A P + +EC + + C G C FTC C GY C E D
Sbjct: 876 LPGFAGPRCARDVDEC-LSNPCGPGTCTDHVASFTCTCPPGYG----GFHC----EQDLP 926
Query: 1515 EAASPLCVNA-RCLNTDGSFRCICRPGFAPTHQPHHCAPARPR 1556
+ + C N C++ SF C+CRPG+ H H P R
Sbjct: 927 DCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSR 969
Score = 176 bits (446), Expect = 2e-43
Identities = 269/1005 (26%), Positives = 351/1005 (34%), Gaps = 202/1005 (20%)
Query: 44 RCVHGPTGSRCTPT---CAPRNATS--VDSGAPGGAAPGGPGFRAFLCPLI--------C 90
RC G TG C CA T G PGF LC + C
Sbjct: 607 RCPSGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPC 666
Query: 91 HNGGVCVKPD---RCLCPPDFAGKFCQLHSSGARPPAPAVPGLTRSVYTMPLANHRDDEH 147
GG CV + RCLCPP G+ PP P + P A H H
Sbjct: 667 GEGGSCVDGENGFRCLCPP------------GSLPPLCLPP-------SHPCA-HEPCSH 706
Query: 148 GVASMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAEAAARAEAAAPYTVLAQSA 207
G+ + P V SGP R + +A +S
Sbjct: 707 GIC------YDAPGGFRCVCEP--GWSGP----------RCSQSLARDAC-------ESQ 741
Query: 208 P-REDGYSDASGFGY---CFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQLCSER 263
P R G + G G+ C ++G +C P T C G +CS
Sbjct: 742 PCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPC--TPNPCEHGGRCESAPGQLPVCS-- 797
Query: 264 LGNSERVSAPDGPCPTGFERVNGSCEDVDECATGGRC-QHGECANTRGGYTCVCPDGFLL 322
CP G++ +DVDECA C HG C N G ++C C G+
Sbjct: 798 -------------CPQGWQGPRCQ-QDVDECAGPAPCGPHGICTNLAGSFSCTCHGGY-- 841
Query: 323 DSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCC--SRVGKAWGRGCQLC 380
+ SC Q + PC L G C + C C G R C
Sbjct: 842 --TGPSC-DQDINDCDPNPC---LNGGSCQ----DGVGSFSCSCLPGFAGPRCARDVDEC 891
Query: 381 --PPFGS-------EGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATS 431
P G F CP G G + DL + P + +
Sbjct: 892 LSNPCGPGTCTDHVASFTCTCPPGYGGFHCEQDLP-DCSPSSCFNGGTCVDGVNSFSCLC 950
Query: 432 RPS-AGFLPTHRLEPRPEPRPDPRPG------PELPLPSIPAWTGPEIPESGPSSGMCQR 484
RP G H +P RP G P + ++TGP+ C R
Sbjct: 951 RPGYTGAHCQHEADPCLS-RPCLHGGVCSAAHPGFRCTCLESFTGPQCQTL---VDWCSR 1006
Query: 485 NPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECR-----RVPPPC-APGRCEN 538
P G GRC+ +G C C G+ R + E R+ C A G+C +
Sbjct: 1007 QPCQNG-GRCVQ--TGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVD 1063
Query: 539 SPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLG-RCENTPGSFLCVCPAGYQAAP 597
S CVC G R G + +VD C + PC G C G ++C C GY
Sbjct: 1064 EDSSHYCVCPEG-RTGSHCEQ--EVDPC--LAQPCQHGGTCRGYMGGYMCECLPGY---- 1114
Query: 598 HGASCQD-VDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPP-PCG 655
+G +C+D VDEC P G G+C +L + C CP G G CE + D+C PP G
Sbjct: 1115 NGDNCEDDVDECASQPCQHG-GSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSG 1173
Query: 656 P-----GRCDNTAGSFHCACPAGFRSRGPGAPCQ-DVDECARSPPPCTYGR--CENTEGS 707
P G C + G F C CP G+ G C+ D++EC + R ++ G
Sbjct: 1174 PRCLHNGTCVDLVGGFRCTCPPGYT----GLRCEADINECRSGACHAAHTRDCLQDPGGG 1229
Query: 708 FQCVCPMGFQPNTAGSECEDV-DECENHLACPGQECVNSPG--SFQCRTCPSGHHLHRGR 764
F+C+C GF +G C+ V CE+ G +C SPG TC R
Sbjct: 1230 FRCLCHAGF----SGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPR 1285
Query: 765 CTDVD------ECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGP---------- 808
C V +C G P C T RC+C PG PS R P
Sbjct: 1286 CERVARSCRELQCPVGVP-------CQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNAS 1338
Query: 809 CADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGIC 868
CA CL G C P F C CA G+ GPR + E SEE C C
Sbjct: 1339 CAAA-PCLHGGSCRP----APLAPFFRCACAQGWT-GPRCEAPAAAPEVSEEPRCPRAAC 1392
Query: 869 TNTDGSFEC---ICPPGHRAGPDLASC-LDV-DECRERGPALC----GSQRCENSPGSYR 919
G C PG G D C L V D R+ C + RC+ + S
Sbjct: 1393 QAKRGDQRCDRECNSPG--CGWDGGDCSLSVGDPWRQCEALQCWRLFNNSRCDPACSSPA 1450
Query: 920 CVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRC 964
C+ D + G E TC+ V E +Y + RC+ + C
Sbjct: 1451 CLYDNFDCHAGGRERTCNPVYE--KYCADHFADGRCDQGCNTEEC 1493
Score = 166 bits (419), Expect = 2e-40
Identities = 251/931 (26%), Positives = 328/931 (35%), Gaps = 192/931 (20%)
Query: 718 PNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPP 777
P A C D C N G C P CP G R C D C SG P
Sbjct: 36 PGAAAPPCLDGSPCAN-----GGRCTQLPSREAACLCPPGWVGER--CQLEDPCHSG--P 86
Query: 778 CGPHGHCTNT----EGSFRCSCAPGYRAPS-GRPGPCADVNECLEGDFCFPHGECLNTDG 832
C G C ++ F C C G+R P P PC + C G C + DG
Sbjct: 87 CAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPCLS-SPCAHGARC-----SVGPDG 140
Query: 833 SFACTCAPGYRPGPRGASCL-DVDECSEEDLCQ-SGICTNTDGSFECICPPGHR------ 884
F C+C PGY+ G SC DVDEC + C+ G C NT GSF C CP G+
Sbjct: 141 RFLCSCPPGYQ----GRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCEN 196
Query: 885 -AGPDLAS-CLDVDECRERGPALCGSQRCENSPG--SYRC---VRDCDPGYHAGPEGTC- 936
A P S C + CR+ G + C PG C V DC PG+ GTC
Sbjct: 197 PAVPCAPSPCRNGGTCRQSGDL---TYDCACLPGFEGQNCEVNVDDC-PGHRCLNGGTCV 252
Query: 937 --------------------DDVDECQEYGPEIC-GAQRCENTPGSYRCTPACDPGYQPT 975
+DVDECQ P C C NT G + C C G+
Sbjct: 253 DGVNTYNCQCPPEWTGQFCTEDVDECQ-LQPNACHNGGTCFNTLGGHSCV--CVNGWT-- 307
Query: 976 PGGGC-QDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEG-------ARDGRHCVDVNE 1027
G C Q++D+C + C A C + SF C C G G A C +
Sbjct: 308 -GESCSQNIDDCAT-AVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAI 365
Query: 1028 CETLQGVCGAALCENVEGSFLCVCPNSPEEFD------PMTGRCVPPRTSAGTFPGSQPQ 1081
C+T V G A+C G C +E GRCV + G+F +
Sbjct: 366 CDT-NPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCV---NTQGSFLCQCGR 421
Query: 1082 APASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECY-FDTAAPDACDNILARNVTWQECC 1140
P R + + G R + D C I T C
Sbjct: 422 GYTGP------------RCETDVNECLSGPCRNQATCLDRIGQFTC--ICMAGFTGTYCE 467
Query: 1141 CTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKS 1200
+ E S C + CP G SG + + DVDEC C++
Sbjct: 468 VDIDECQSSPCVNGGVCKDRVNGFSCTCPSGF-----SGS-TCQLDVDECA---STPCRN 518
Query: 1201 GV-CVNTAPGYSCYCSNGYYYHTQRLECIDN-DECADEEPACEGGRCVNTVGSYHCTCEP 1258
G CV+ GY C C+ G+ + C N D+C+ + C GRCV+ + S+ C C P
Sbjct: 519 GAKCVDQPDGYECRCAEGF----EGTLCDRNVDDCSPDP--CHHGRCVDGIASFSCACAP 572
Query: 1259 PLVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHPR----LDRQATYTECC---CL 1311
G++ +E +S G ++ +C P ++ + +C C
Sbjct: 573 GYT--GTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCT 630
Query: 1312 YGEAWG----MDCALCPAQDSDDFEALCNV-LRPPAYSPPRPGGFGLPYEYGPDLGPPYQ 1366
+G DC P LCNV + A SP GG + E G P
Sbjct: 631 FGVCRDGINRYDCVCQPGFTGP----LCNVEINECASSPCGEGGSCVDGENGFRCLCPPG 686
Query: 1367 GLPYGPELYPPPALP--YDP------YPPPPGPFARREAPYGAPRFDMPDFEDD------ 1412
LP L PP+ P ++P Y P G E + PR D
Sbjct: 687 SLP---PLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPC 743
Query: 1413 --GGPYGES----EAPAPPGPGTRWPYRSRDTRRSFPEPEEPPEGG----SYAGSLAE-- 1460
GG PPG + R P P E G S G L
Sbjct: 744 RAGGTCSSDGMGFHCTCPPG------VQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCS 797
Query: 1461 -------PYEELEAEECGILDGC-TNGRCVRVPEGFTCRCFDGYRLDMTRMAC-VDINEC 1511
P + + +EC C +G C + F+C C GY T +C DIN+C
Sbjct: 798 CPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGY----TGPSCDQDINDC 853
Query: 1512 DEAEAASPLCVNARCLNTDGSFRCICRPGFA 1542
D +P C + GSF C C PGFA
Sbjct: 854 DP----NPCLNGGSCQDGVGSFSCSCLPGFA 880
Score = 98.2 bits (243), Expect = 5e-20
Identities = 219/939 (23%), Positives = 296/939 (31%), Gaps = 216/939 (23%)
Query: 42 GLRCVHGPTGSRCT-------PTCAPRNATSVDSGAPGGA---APGG------PGFRAFL 85
G CV G G RC P C P + G APGG PG+
Sbjct: 669 GGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPR 728
Query: 86 CPLI----------CHNGGVCVKPD---RCLCPPDFAGKFCQLHSSGARPPAPAVPGLTR 132
C C GG C C CPP G+ C+L S P P
Sbjct: 729 CSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLS-------PCTPN--- 778
Query: 133 SVYTMPLANHRDDEHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAEAAA 192
P + E + + V+ +GP +
Sbjct: 779 -----PCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSF 833
Query: 193 RAEAAAPYTVLAQSAPREDGYSDASGFGYCFRELRGGECASPLPGLRTQEVCCRGAGLAW 252
YT + D + G ++ G S LPG G A
Sbjct: 834 SCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGF-------AGPRCAR 886
Query: 253 GVHDCQLCSERLGN---SERVSAPDGPCPTGFERVNGSCE-DVDECATGGRCQHGECANT 308
V +C S G ++ V++ CP G+ + CE D+ +C+ G C +
Sbjct: 887 DVDEC--LSNPCGPGTCTDHVASFTCTCPPGYGGFH--CEQDLPDCSPSSCFNGGTCVDG 942
Query: 309 RGGYTCVCPDGFL---LDSSRSSCISQHVISEAKGPCFRVLRDGGCS-------LPILRN 358
++C+C G+ C+S+ PC L G CS L +
Sbjct: 943 VNSFSCLCRPGYTGAHCQHEADPCLSR--------PC---LHGGVCSAAHPGFRCTCLES 991
Query: 359 ITKQIC-----CCSRVGKAWGRGCQ------LCPPFGSEG-------------------- 387
T C CSR G C LCPP G G
Sbjct: 992 FTGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCPP-GWSGRLCDIRSLPCREAAAQIGVR 1050
Query: 388 FREICPAGPGYHYSASDLRYNTRPLG------QEPPRVSLSQPRTLPATSRPSAGFLPTH 441
++C AG G Y P G ++ L+QP T R G++ +
Sbjct: 1051 LEQLCQAG-GQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCR---GYMGGY 1106
Query: 442 RLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGY 501
E +P + G + C P G G CI + Y
Sbjct: 1107 MCE------------------CLPGYNGDNCEDDVDE---CASQPCQHG-GSCIDLVARY 1144
Query: 502 TCACDSGFRLSPQGTRC-IDVDECRRVPP-PCAP-----GRCENSPGSFRCVCGPGFRAG 554
C+C G G C I+ D+C PP P G C + G FRC C PG+ G
Sbjct: 1145 LCSCPPG----TLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGY-TG 1199
Query: 555 PRAAECLDVDECHRVPPPCDLGR---CENTP-GSFLCVCPAGYQAAPHGASCQDV-DECT 609
R D++EC C C P G F C+C AG+ G CQ V C
Sbjct: 1200 LRCE--ADINECR--SGACHAAHTRDCLQDPGGGFRCLCHAGFS----GPRCQTVLSPCE 1251
Query: 610 QSPGLCGRGACKNLPG-----SFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAG 664
P G G C+ PG +F C C F G CE C + P G C T
Sbjct: 1252 SQPCQHG-GQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGV-PCQQTPR 1309
Query: 665 SFHCACPAGFRSRG----PGAPCQDVDECARSPPPCTYG---RCENTEGSFQCVCPMGFQ 717
CACP G PG+P + + PC +G R F+C C G+
Sbjct: 1310 GPRCACPPGLSGPSCRSFPGSP-PGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGW- 1367
Query: 718 PNTAGSECE---DVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSG 774
G CE E CP C G +C EC+S
Sbjct: 1368 ---TGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRCDR----------------ECNS- 1407
Query: 775 APPCG-PHGHCTNTEGS--FRCSCAPGYRA-PSGRPGPCADVNECLEGDF-CFPHGECLN 829
P CG G C+ + G +C +R + R P CL +F C G
Sbjct: 1408 -PGCGWDGGDCSLSVGDPWRQCEALQCWRLFNNSRCDPACSSPACLYDNFDCHAGGRERT 1466
Query: 830 TDGSFACTCAPGYRPGPRGASCLDVDECSEEDL-CQSGI 867
+ + CA + G C + +EC + L C S +
Sbjct: 1467 CNPVYEKYCADHFADGRCDQGC-NTEECGWDGLDCASEV 1504
Score = 56.2 bits (134), Expect = 2e-07
Identities = 37/101 (36%), Positives = 46/101 (45%), Gaps = 21/101 (20%)
Query: 222 CFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPTGF 281
C R RG +C+ P P L + C GA + G LCS CP G+
Sbjct: 108 CPRGFRGPDCSLPDPCLSSP--CAHGARCSVGPDGRFLCS---------------CPPGY 150
Query: 282 ERVNGSCE-DVDECATGGRCQHG-ECANTRGGYTCVCPDGF 320
+ SC DVDEC G C+HG C NT G + C CP G+
Sbjct: 151 Q--GRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGY 189
Score = 43.1 bits (100), Expect = 0.002
Identities = 27/67 (40%), Positives = 32/67 (47%), Gaps = 8/67 (11%)
Query: 1478 NGRCVRVPEGFTCRCFDGYRLDMTRMAC-VDINECDEAEAASPLCVNARCL-NTDGSFRC 1535
NG CV + GF C C GY T + C DINEC A CL + G FRC
Sbjct: 1179 NGTCVDLVGGFRCTCPPGY----TGLRCEADINEC--RSGACHAAHTRDCLQDPGGGFRC 1232
Query: 1536 ICRPGFA 1542
+C GF+
Sbjct: 1233 LCHAGFS 1239
Score = 42.7 bits (99), Expect = 0.003
Identities = 31/95 (32%), Positives = 44/95 (46%), Gaps = 13/95 (13%)
Query: 1464 ELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMAC-VDINECDEAEAASPLCV 1522
E+ ++C + CT G C + C C G+ T C V+INEC A+SP
Sbjct: 618 EVNIDDCAS-NPCTFGVCRDGINRYDCVCQPGF----TGPLCNVEINEC----ASSPCGE 668
Query: 1523 NARCLNTDGSFRCICRPGFAPTHQPHHCAPARPRA 1557
C++ + FRC+C PG P P P+ P A
Sbjct: 669 GGSCVDGENGFRCLCPPGSLP---PLCLPPSHPCA 700
Score = 36.6 bits (83), Expect = 0.19
Identities = 24/83 (28%), Positives = 35/83 (42%), Gaps = 10/83 (12%)
Query: 1464 ELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEA----ASP 1519
E + +EC G C+ + + C C G T +INE D + P
Sbjct: 1120 EDDVDECASQPCQHGGSCIDLVARYLCSCPPG-----TLGVLCEINEDDCGPGPPLDSGP 1174
Query: 1520 LCV-NARCLNTDGSFRCICRPGF 1541
C+ N C++ G FRC C PG+
Sbjct: 1175 RCLHNGTCVDLVGGFRCTCPPGY 1197
Score = 35.8 bits (81), Expect = 0.33
Identities = 23/53 (43%), Positives = 26/53 (49%), Gaps = 18/53 (33%)
Query: 71 PGGAAP----GGPGFRAFLCPLICHNGGVCVK-PDR---CLCPPDFAGKFCQL 115
PG AAP G P C NGG C + P R CLCPP + G+ CQL
Sbjct: 36 PGAAAPPCLDGSP----------CANGGRCTQLPSREAACLCPPGWVGERCQL 78
Score = 35.8 bits (81), Expect = 0.33
Identities = 30/95 (31%), Positives = 35/95 (36%), Gaps = 18/95 (18%)
Query: 37 TPVVCGLRCVHGPTGSRC---TPTCAP----RNATSVDSGAPGGAAPGGPGFRAFLCPLI 89
TP +C G TG C CAP T SG PGF C +
Sbjct: 177 TPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVN 236
Query: 90 --------CHNGGVCV---KPDRCLCPPDFAGKFC 113
C NGG CV C CPP++ G+FC
Sbjct: 237 VDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFC 271
Score = 33.1 bits (74), Expect = 2.1
Identities = 21/77 (27%), Positives = 29/77 (37%), Gaps = 7/77 (9%)
Query: 1464 ELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 1523
E E + C G C G+ C C GY D D++EC A+ P
Sbjct: 1082 EQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCE---DDVDEC----ASQPCQHG 1134
Query: 1524 ARCLNTDGSFRCICRPG 1540
C++ + C C PG
Sbjct: 1135 GSCIDLVARYLCSCPPG 1151
Score = 32.3 bits (72), Expect = 3.7
Identities = 28/104 (26%), Positives = 35/104 (33%), Gaps = 28/104 (26%)
Query: 37 TPVVCGLRCVHGPTGS---RCTPTCAPRNATS-VDSGAPGGAAPGGPGFRAFLCPLICHN 92
+P G RC GP G C P R+ S VD G C +
Sbjct: 126 SPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEP---------------CRH 170
Query: 93 GGVCVKPD---RCLCPPDFAGKFCQLHSSGARPPAPAVPGLTRS 133
GG C+ RC CP + G C+ P P P R+
Sbjct: 171 GGTCLNTPGSFRCQCPAGYTGPLCE------NPAVPCAPSPCRN 208
Score = 32.3 bits (72), Expect = 3.7
Identities = 15/29 (51%), Positives = 16/29 (55%), Gaps = 3/29 (10%)
Query: 90 CHNGGVC---VKPDRCLCPPDFAGKFCQL 115
C NGGVC V C CP F+G CQL
Sbjct: 478 CVNGGVCKDRVNGFSCTCPSGFSGSTCQL 506
>gi|51873053 fibulin 2 isoform a precursor [Homo sapiens]
Length = 1231
Score = 282 bits (722), Expect = 2e-75
Identities = 236/740 (31%), Positives = 309/740 (41%), Gaps = 131/740 (17%)
Query: 424 PRTLPATSRPSAGFLPTHRLEPR-PEPRP--------DPRPGPELPLPSIPAWTGP---- 470
P + +TS P A ++P R PR P+ P DP +P S T
Sbjct: 385 PHNILSTSLPDAAWIPPTREVPRKPQVLPHSHVEEDTDPNSVHSIPRSSPEGSTKDLIET 444
Query: 471 ----------------EIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQ 514
EIPESG +C+ + C C+S +C +G + +
Sbjct: 445 CCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHC----CVSYLQEKSCM--AGVLGAKE 498
Query: 515 GTRC--IDVDEC-----RRVPPPCAPG--------RCENSPGSFRCVCGPGFRAGPRAAE 559
G C D D C ++ C G CE++P + C + E
Sbjct: 499 GETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQSCESNP-NLGYPCNHVMLSCCEGEE 557
Query: 560 CLDVDECHRVPPPCDLGR--CENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGR 617
L V E R P P R E + P+ D DEC PG +
Sbjct: 558 PLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQDECLLLPGELCQ 617
Query: 618 GACKNLPGSFRCVCPAGFR----GSACEED----VDECAQEPP----------------- 652
C N GS+ C C GF G C + E QEP
Sbjct: 618 HLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIPLPL 677
Query: 653 ----PC---GPGR--CDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGR-CE 702
C GP + C GS C+C G+ G C+D DEC C+ + C
Sbjct: 678 PQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCV 737
Query: 703 NTEGSFQCV-----CPMGFQPNTAGSECEDVDEC--ENHLACPGQECVNSPGSFQCR--- 752
NT GSF CV C G+ N A +C D++EC + H G+ CVN+ GSF C
Sbjct: 738 NTLGSFYCVNHTVLCADGYILN-AHRKCVDINECVTDLHTCSRGEHCVNTLGSFHCYKAL 796
Query: 753 TCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCS----CAPGY-RAPSGRPG 807
TC G+ L G C DVDEC+ G C P C NT+GSF C C G+ + P G
Sbjct: 797 TCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGN-- 854
Query: 808 PCADVNECLE-GDFCFPHGECLNTDGSFACT-----CAPGYRPGPRGASCLDVDECSEE- 860
C D+NEC + C P C+NT GS+ C CA GY G C+DV+EC
Sbjct: 855 -CVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGV 913
Query: 861 DLCQSG-ICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYR 919
C G +C N GS+ C C G + C+DV+EC LC CEN+ GSYR
Sbjct: 914 HRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLC-QHTCENTLGSYR 972
Query: 920 CVRDCDPGYHAGPEGT-CDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGG 978
C C G+ +G C+DV+EC+ + C +Q C N GSY+C C GYQ G
Sbjct: 973 C--SCASGFLLAADGKRCEDVNECEA---QRC-SQECANIYGSYQCY--CRQGYQLAEDG 1024
Query: 979 G-CQDVDECRNRSFCGAHAVCQNLPGSFQCLC-DQGYEGARDGRHCVDVNECETLQGVCG 1036
C D+DEC + C N+PGS+QC C +QGY +GR C DV+EC C
Sbjct: 1025 HTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCS 1084
Query: 1037 -AALCENVEGSFLCV---CP 1052
A C N++GSF C+ CP
Sbjct: 1085 EAETCHNIQGSFRCLRFECP 1104
Score = 275 bits (703), Expect = 2e-73
Identities = 217/682 (31%), Positives = 285/682 (41%), Gaps = 101/682 (14%)
Query: 358 NITKQICCCSRVG---KAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQ 414
++ KQ C C +G +A G+ C+ P G P H S G+
Sbjct: 513 SLYKQCCDCCGLGLRVRAEGQSCESNPNLGY----------PCNHVMLSCCE------GE 556
Query: 415 EPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLP---SIPAWTGPE 471
EP V P RP PEP PR E + ++ T E
Sbjct: 557 EPLIV--------PEVRRP-------------PEPAAAPRRVSEAEMAGREALSLGTEAE 595
Query: 472 IPESGPSSGM--CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPP 529
+P S P C P CI+ Y CAC GF L G C +
Sbjct: 596 LPNSLPGDDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEA 655
Query: 530 PCAPG-RCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCV 588
P P + E S + + P P+ C D C +V C GS +C
Sbjct: 656 PQEPALKSEFSQVASNTIPLPL----PQPNTCKDNGPCKQV--------CSTVGGSAICS 703
Query: 589 CPAGYQAAPHGASCQDVDECTQSPGLCGRGA-CKNLPGSFRCV-----CPAGFRGSACEE 642
C GY G SC+D DEC C R C N GSF CV C G+ +A +
Sbjct: 704 CFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRK 763
Query: 643 --DVDECAQEPPPCGPGR-CDNTAGSFHC----ACPAGFRSRGPGAPCQDVDECARSPPP 695
D++EC + C G C NT GSFHC C G+ + C+DVDECA
Sbjct: 764 CVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKD--GECEDVDECAMGTHT 821
Query: 696 CTYG-RCENTEGSFQCV----CPMGFQPNTAGSECEDVDECEN--HLACPGQECVNSPGS 748
C G C+NT+GSF C C GF + G+ C D++EC + PG C+N+ GS
Sbjct: 822 CQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGN-CVDINECTSLSEPCRPGFSCINTVGS 880
Query: 749 FQCRT----CPSGHHLHRG--RCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAP 802
+ C+ C G+H +C DV+EC +G CG C N GS+RC C G++
Sbjct: 881 YTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRD 940
Query: 803 SGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDL 862
+ G C DVNEC C NT GS+ C+CA G+ G C DV+EC +
Sbjct: 941 AFGRG-CIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRC 999
Query: 863 CQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVR 922
Q C N GS++C C G++ D +C D+DEC + LC + RC N PGSY+C
Sbjct: 1000 SQE--CANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILC-TFRCLNVPGSYQCAC 1056
Query: 923 DCDPGYHAGPEG-TCDDVDECQEYGPEICGAQRCENTPGSYRCTP-ACDPGYQPTPGGGC 980
+ GY G +C DVDEC A+ C N GS+RC C P Y C
Sbjct: 1057 P-EQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKC 1115
Query: 981 QDVDECRNRSFCGAHAVCQNLP 1002
+ R+ C CQN P
Sbjct: 1116 E-------RTTCHDFLECQNSP 1130
Score = 176 bits (445), Expect = 2e-43
Identities = 228/891 (25%), Positives = 311/891 (34%), Gaps = 160/891 (17%)
Query: 430 TSRPSAGFLPTHRLEPRPEPRPDPRPGPE----LPLPSIPAWTGPEIPESGPSSGMCQRN 485
T+ P+ LP R + PE L + TGPE PS G
Sbjct: 309 TTAPAGPSLPIQEERAEAGARAEAGARPEENLILDAQATSRSTGPEGVTHAPSLGKAALV 368
Query: 486 PQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPC-APGRCENSPGSFR 544
P PG + + SP + + +PP P + + P S
Sbjct: 369 PTQAVPG-----------SPRDPVKPSPHNILSTSLPDAAWIPPTREVPRKPQVLPHS-- 415
Query: 545 CVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQD 604
E D + H +P G +T C AG Q A C +
Sbjct: 416 -----------HVEEDTDPNSVHSIPRSSPEG---STKDLIETCCAAGQQWAIDNDECLE 461
Query: 605 VDECTQSPGLCGRGACKNLPGSF--RCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNT 662
+ E +C R A ++ S+ C AG G A+E CG D+
Sbjct: 462 IPESGTEDNVC-RTAQRHCCVSYLQEKSCMAGVLG----------AKEGETCGAEDNDSC 510
Query: 663 AGSFH---C-ACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQP 718
S + C C G R R G C+ PC + EG + P +P
Sbjct: 511 GISLYKQCCDCCGLGLRVRAEGQSCESNPNLGY---PCNHVMLSCCEGEEPLIVPEVRRP 567
Query: 719 NTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPC 778
+ V E E G+E ++ + G D DEC
Sbjct: 568 PEPAAAPRRVSEAE----MAGREALSLGTEAELPNSLPGD--------DQDECLLLPGEL 615
Query: 779 GPHGHCTNTEGSFRCSCAPGYRA--------PSGRPG-PCADVNECLEGDF--------- 820
H C NT GS+ C+C PG+ P G P P A L+ +F
Sbjct: 616 CQH-LCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIP 674
Query: 821 --------CFPHGECLNT----DGSFACTCAPGYRPGPRGASCLDVDEC--SEEDLCQSG 866
C +G C GS C+C PGY G SC D DEC D +
Sbjct: 675 LPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQ 734
Query: 867 ICTNTDGSFECI-----CPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCV 921
C NT GSF C+ C G+ C+D++EC + C N+ GS+ C
Sbjct: 735 FCVNTLGSFYCVNHTVLCADGYILNAH-RKCVDINECVTDLHTCSRGEHCVNTLGSFHCY 793
Query: 922 R--DCDPGYHAGPEGTCDDVDECQEYGPEICGAQ-RCENTPGSYRCTPA--CDPGYQPTP 976
+ C+PGY A +G C+DVDEC G C C+NT GS+ C C G+ P
Sbjct: 794 KALTCEPGY-ALKDGECEDVDECA-MGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDP 851
Query: 977 GGGCQDVDECRNRSF-CGAHAVCQNLPGSFQC-----LCDQGYEGARDGRHCVDVNECET 1030
G C D++EC + S C C N GS+ C +C +GY + DG CVDVNECET
Sbjct: 852 EGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECET 911
Query: 1031 LQGVCGAA-LCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLP 1089
CG +C N+ GS+ C C + D C+ + PG Q L
Sbjct: 912 GVHRCGEGQVCHNLPGSYRCDCKAGFQR-DAFGRGCIDVNECWAS-PGRLCQHTCENTLG 969
Query: 1090 ARPPPPPLPRRPSTPRQGPVGSGRRECY-FDTAAPDACDNILARNVTWQECCCTVG---- 1144
+ R S + + + C + C A +C C G
Sbjct: 970 SY--------RCSCASGFLLAADGKRCEDVNECEAQRCSQECANIYGSYQCYCRQGYQLA 1021
Query: 1145 -------------EGWGSGC--RIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDE 1189
+G G C R PG+ YQ CP +GY + S + DVDE
Sbjct: 1022 EDGHTCTDIDECAQGAGILCTFRCLNVPGS----YQCACPE-QGYTMTANGRSCK-DVDE 1075
Query: 1190 CQLFRDQVCKSGVCVNTAPGYSCY---CSNGYYY----HTQRLECIDNDEC 1233
C L ++ C N + C C Y +R C D EC
Sbjct: 1076 CALGTHNCSEAETCHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLEC 1126
Score = 79.0 bits (193), Expect = 3e-14
Identities = 115/456 (25%), Positives = 156/456 (34%), Gaps = 117/456 (25%)
Query: 853 DVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCE 912
D D S + +S +T E C G + D CL++ E +QR
Sbjct: 420 DTDPNSVHSIPRSSPEGSTKDLIETCCAAGQQWAIDNDECLEIPESGTEDNVCRTAQR-- 477
Query: 913 NSPGSYRCVRDCDPGYHAGPEG-TC--DDVDEC----QEYGPEICG--------AQRCEN 957
+ SY + C G EG TC +D D C + + CG Q CE+
Sbjct: 478 HCCVSYLQEKSCMAGVLGAKEGETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQSCES 537
Query: 958 TPG-SYRCTP---ACDPGYQPT----------PGGGCQDVDEC----RNRSFCGAHAVCQ 999
P Y C +C G +P P + V E R G A
Sbjct: 538 NPNLGYPCNHVMLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELP 597
Query: 1000 N-LPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEF 1058
N LPG D +EC L G LC N GS+ C C
Sbjct: 598 NSLPGD-------------------DQDECLLLPGELCQHLCINTVGSYHCAC------- 631
Query: 1059 DPMTGRCVPPRTSAGTFPGSQPQAPASPVLP-ARPPPPPLPRRPSTPRQ-GPVGSGRREC 1116
FPG Q P PP P P+ P+ + V S
Sbjct: 632 ----------------FPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIP- 674
Query: 1117 YFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLA 1176
P+ C + N ++ C TVG GS ++C GY
Sbjct: 675 -LPLPQPNTCKD----NGPCKQVCSTVG---GS----------------AICSCFPGYAI 710
Query: 1177 PSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCY-----CSNGYYYHTQRLECIDND 1231
+ +S D DEC + + CVNT + C C++GY + R +C+D +
Sbjct: 711 MADGVSCE-DQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHR-KCVDIN 768
Query: 1232 ECADEEPACEGGR-CVNTVGSYHC----TCEPPLVL 1262
EC + C G CVNT+GS+HC TCEP L
Sbjct: 769 ECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYAL 804
Score = 63.2 bits (152), Expect = 2e-09
Identities = 60/232 (25%), Positives = 89/232 (38%), Gaps = 42/232 (18%)
Query: 1126 CDNILARNVTWQECCCTVGEGWGSG-CR-IQQCP-GTETAEYQSLCPHGRGYLA------ 1176
C N L ++ C G G C + +C GT T + LC + +G
Sbjct: 783 CVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQR 842
Query: 1177 --------PSGDLSLRRDVDECQLFRDQVCKSGV-CVNTAPGYSCY-----CSNGYYYHT 1222
P G+ D++EC + C+ G C+NT Y+C C+ GY+
Sbjct: 843 CMDGFLQDPEGNCV---DINECTSLSEP-CRPGFSCINTVGSYTCQRNPLICARGYHASD 898
Query: 1223 QRLECIDNDECADEEPAC-EGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNL 1281
+C+D +EC C EG C N GSY C C+ D R C+ ++
Sbjct: 899 DGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCI---------DV 949
Query: 1282 GVCWQEVGADLVCSHPRLDRQATYTECCCLYGEAWGMDCALCPAQDSDDFEA 1333
CW G +C H + +Y C C G D C +D ++ EA
Sbjct: 950 NECWASPGR--LCQHTCENTLGSY-RCSCASGFLLAADGKRC--EDVNECEA 996
Score = 56.2 bits (134), Expect = 2e-07
Identities = 70/283 (24%), Positives = 104/283 (36%), Gaps = 54/283 (19%)
Query: 85 LCPLICHNGGVCVKPDRCLCPPDFA----GKFCQLHSSGARPPAPAVPGLTRSVYTMPLA 140
LC +C N V C C P F+ G+ C+ +P AP P L +S ++ +
Sbjct: 615 LCQHLCIN---TVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPAL-KSEFSQVAS 670
Query: 141 NHRDDEHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAEAAARAEAAAPY 200
N ++ + PQ + + +GP ++ + +A Y
Sbjct: 671 N------------TIPLPLPQPNTC------KDNGPCKQV----CSTVGGSAICSCFPGY 708
Query: 201 TVLAQSAPRED------GYSDASGFGYCFRELRGGECASPLPG------LRTQEVCCRGA 248
++A ED G D S +C L C + L C
Sbjct: 709 AIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCVDIN 768
Query: 249 GLAWGVHDC---QLCSERLGNSERVSAPDGPCPTGFERVNGSCEDVDECATGGR-CQHG- 303
+H C + C LG+ A C G+ +G CEDVDECA G CQ G
Sbjct: 769 ECVTDLHTCSRGEHCVNTLGSFHCYKALT--CEPGYALKDGECEDVDECAMGTHTCQPGF 826
Query: 304 ECANTRGGYTCV----CPDGFLLDSSRSSCISQHVISEAKGPC 342
C NT+G + C C DGFL D +C+ + + PC
Sbjct: 827 LCQNTKGSFYCQARQRCMDGFLQD-PEGNCVDINECTSLSEPC 868
Score = 53.5 bits (127), Expect = 2e-06
Identities = 32/96 (33%), Positives = 42/96 (43%), Gaps = 11/96 (11%)
Query: 1456 GSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAE 1515
G E E EA+ C + C + + C C GY+L C DI+EC A+
Sbjct: 985 GKRCEDVNECEAQRC-------SQECANIYGSYQCYCRQGYQLAEDGHTCTDIDEC--AQ 1035
Query: 1516 AASPLCVNARCLNTDGSFRCIC-RPGFAPTHQPHHC 1550
A LC RCLN GS++C C G+ T C
Sbjct: 1036 GAGILC-TFRCLNVPGSYQCACPEQGYTMTANGRSC 1070
Score = 49.7 bits (117), Expect = 2e-05
Identities = 28/69 (40%), Positives = 37/69 (53%), Gaps = 8/69 (11%)
Query: 1476 CTNGR-CVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASP--LCVNARCLNTDGS 1532
C G+ C +P + C C G++ D C+D+NEC ASP LC + C NT GS
Sbjct: 916 CGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNEC----WASPGRLCQHT-CENTLGS 970
Query: 1533 FRCICRPGF 1541
+RC C GF
Sbjct: 971 YRCSCASGF 979
Score = 49.3 bits (116), Expect = 3e-05
Identities = 36/84 (42%), Positives = 41/84 (48%), Gaps = 14/84 (16%)
Query: 253 GVHDC---QLCSERLGNSERVSAPDGPCPTGFER--VNGSCEDVDEC-ATGGR-CQHGEC 305
GVH C Q+C L S R C GF+R C DV+EC A+ GR CQH C
Sbjct: 912 GVHRCGEGQVC-HNLPGSYRCD-----CKAGFQRDAFGRGCIDVNECWASPGRLCQH-TC 964
Query: 306 ANTRGGYTCVCPDGFLLDSSRSSC 329
NT G Y C C GFLL + C
Sbjct: 965 ENTLGSYRCSCASGFLLAADGKRC 988
Score = 47.0 bits (110), Expect = 1e-04
Identities = 63/284 (22%), Positives = 95/284 (33%), Gaps = 29/284 (10%)
Query: 1009 CDQGYEGARDGRHC--VDVNEC-----ETLQGVCGAALCENVEGSFLCVCPNSPEEFDPM 1061
C G GA++G C D + C + CG L EG PN + +
Sbjct: 489 CMAGVLGAKEGETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHV 548
Query: 1062 TGRC-------VPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRR 1114
C + P P + P+ + + R L P P G +
Sbjct: 549 MLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALS-LGTEAELPNSLP-GDDQD 606
Query: 1115 ECYFDTAAPDACDNILARNVTWQECCCTVG---EGWGSGCRIQQCPGTETAEYQSLCPHG 1171
EC + C ++ V C C G + G CR + P A + P
Sbjct: 607 ECLL--LPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQE---PAL 661
Query: 1172 RGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDND 1231
+ + ++ + + +D VC C C GY + C D D
Sbjct: 662 KSEFSQVASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQD 721
Query: 1232 ECADEEPACEGGR-CVNTVGSYHCTCEPPLVLDG----SQRRCV 1270
EC C + CVNT+GS++C L DG + R+CV
Sbjct: 722 ECLMGAHDCSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRKCV 765
Score = 46.2 bits (108), Expect = 2e-04
Identities = 32/103 (31%), Positives = 45/103 (43%), Gaps = 16/103 (15%)
Query: 1452 GSYAGSLAEPYEELE-AEECGILDGCTNG-------RCVRVPEGFTCRCFD-GYRLDMTR 1502
GSY + Y+ E C +D C G RC+ VP + C C + GY +
Sbjct: 1008 GSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANG 1067
Query: 1503 MACVDINECDEAEAASPLCVNAR-CLNTDGSFRCI---CRPGF 1541
+C D++EC + C A C N GSFRC+ C P +
Sbjct: 1068 RSCKDVDEC---ALGTHNCSEAETCHNIQGSFRCLRFECPPNY 1107
Score = 45.8 bits (107), Expect = 3e-04
Identities = 27/88 (30%), Positives = 37/88 (42%), Gaps = 9/88 (10%)
Query: 1465 LEAEECGILDG--CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCV 1522
++ EC G C + C + C C G+ L C D+NEC EA+ S
Sbjct: 947 IDVNECWASPGRLCQH-TCENTLGSYRCSCASGFLLAADGKRCEDVNEC-EAQRCSQ--- 1001
Query: 1523 NARCLNTDGSFRCICRPGFAPTHQPHHC 1550
C N GS++C CR G+ H C
Sbjct: 1002 --ECANIYGSYQCYCRQGYQLAEDGHTC 1027
Score = 44.7 bits (104), Expect = 7e-04
Identities = 36/115 (31%), Positives = 44/115 (38%), Gaps = 22/115 (19%)
Query: 1454 YAGSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTC-------------RCFDGYRLDM 1500
Y EP L+ EC +D C G P GF C RC DG+ D
Sbjct: 793 YKALTCEPGYALKDGECEDVDECAMGTHTCQP-GFLCQNTKGSFYCQARQRCMDGFLQD- 850
Query: 1501 TRMACVDINECDEAEAASPLCVNARCLNTDGSFRC-----ICRPGFAPTHQPHHC 1550
CVDINEC + P C+NT GS+ C IC G+ + C
Sbjct: 851 PEGNCVDINEC--TSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKC 903
Score = 43.1 bits (100), Expect = 0.002
Identities = 28/85 (32%), Positives = 38/85 (44%), Gaps = 11/85 (12%)
Query: 1465 LEAEECGIL-DGCTNG-RCVRVPEGFTCR-----CFDGYRLDMTRMACVDINECDEAEAA 1517
++ EC L + C G C+ +TC+ C GY CVD+NEC E
Sbjct: 856 VDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNEC---ETG 912
Query: 1518 SPLCVNAR-CLNTDGSFRCICRPGF 1541
C + C N GS+RC C+ GF
Sbjct: 913 VHRCGEGQVCHNLPGSYRCDCKAGF 937
Score = 41.6 bits (96), Expect = 0.006
Identities = 90/377 (23%), Positives = 116/377 (30%), Gaps = 89/377 (23%)
Query: 1228 IDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQE 1287
IDNDEC + + G+ C +QR C + Q GV +
Sbjct: 454 IDNDECLE----------IPESGTEDNVCRT------AQRHCCVSYLQEKSCMAGVLGAK 497
Query: 1288 VGADLVCSHPRLDRQATYTECCCLYG-----EAWGMDCALCPAQDSDDFEALCN------ 1336
G + Y +CC G A G C + + + CN
Sbjct: 498 EGETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQSC-----ESNPNLGYPCNHVMLSC 552
Query: 1337 ------VLRPPAYSPPRPGGFGLPYEYGPDLGPPYQGLPYGPELYPPPALPYDPYPPP-- 1388
++ P PP P P + L G E P +LP D
Sbjct: 553 CEGEEPLIVPEVRRPPEPAA--APRRVSEAEMAGREALSLGTEAELPNSLPGDDQDECLL 610
Query: 1389 -PGPFARR-----EAPYGAPRFDMPDFEDDGG---PYGESEAP-APPGPGTRWPYRSRDT 1438
PG + Y F +DDG P G P AP P + + S+
Sbjct: 611 LPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEF-SQVA 669
Query: 1439 RRSFPEPEEPPE---------------GGSYAGSLAEPYEEL-EAEECGILDGCTNGR-- 1480
+ P P P GGS S Y + + C D C G
Sbjct: 670 SNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHD 729
Query: 1481 ------CVRVPEGFTC-----RCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNT 1529
CV F C C DGY L+ R CVDINEC C+NT
Sbjct: 730 CSRRQFCVNTLGSFYCVNHTVLCADGYILNAHRK-CVDINEC--VTDLHTCSRGEHCVNT 786
Query: 1530 DGSFRC----ICRPGFA 1542
GSF C C PG+A
Sbjct: 787 LGSFHCYKALTCEPGYA 803
Score = 41.6 bits (96), Expect = 0.006
Identities = 38/127 (29%), Positives = 46/127 (36%), Gaps = 20/127 (15%)
Query: 257 CQLCSERLGNSERVSAPDGPCPTGFERVNGS--CEDVDECATGGRCQHGECANTRGGYTC 314
CQ E S R S C +GF CEDV+EC RC ECAN G Y C
Sbjct: 960 CQHTCENTLGSYRCS-----CASGFLLAADGKRCEDVNECEAQ-RCSQ-ECANIYGSYQC 1012
Query: 315 VCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVG---K 371
C G+ L +C ++ G C+ L C C G
Sbjct: 1013 YCRQGYQLAEDGHTCTDIDECAQGAGIL--------CTFRCLNVPGSYQCACPEQGYTMT 1064
Query: 372 AWGRGCQ 378
A GR C+
Sbjct: 1065 ANGRSCK 1071
Score = 36.2 bits (82), Expect = 0.25
Identities = 32/96 (33%), Positives = 47/96 (48%), Gaps = 23/96 (23%)
Query: 244 CCRGAGLAWGVHDCQLCSERLGN---SERVSAPDGPCPTGFERV-NG-SCEDVDECATG- 297
C +GAG+ LC+ R N S + + P+ G+ NG SC+DVDECA G
Sbjct: 1033 CAQGAGI--------LCTFRCLNVPGSYQCACPE----QGYTMTANGRSCKDVDECALGT 1080
Query: 298 GRCQHGE-CANTRGGYTCV---CPDGFLLDSSRSSC 329
C E C N +G + C+ CP + + S++ C
Sbjct: 1081 HNCSEAETCHNIQGSFRCLRFECPPNY-VQVSKTKC 1115
Score = 35.8 bits (81), Expect = 0.33
Identities = 19/43 (44%), Positives = 21/43 (48%), Gaps = 3/43 (6%)
Query: 289 EDVDECAT--GGRCQHGECANTRGGYTCVCPDGFLLDSSRSSC 329
+D DEC G CQH C NT G Y C C GF L +C
Sbjct: 603 DDQDECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTC 644
Score = 32.3 bits (72), Expect = 3.7
Identities = 12/27 (44%), Positives = 15/27 (55%)
Query: 1526 CLNTDGSFRCICRPGFAPTHQPHHCAP 1552
C+NT GS+ C C PGF+ C P
Sbjct: 620 CINTVGSYHCACFPGFSLQDDGRTCRP 646
>gi|148833508 notch1 preproprotein [Homo sapiens]
Length = 2555
Score = 279 bits (714), Expect = 1e-74
Identities = 372/1415 (26%), Positives = 518/1415 (36%), Gaps = 297/1415 (20%)
Query: 7 LLWVSLLVLLAQLGP---QPGLGRL-GERLRVRFTPVVC-------GLRCVHGPTGSRCT 55
LL ++LL LA GP QPG L G + C G RC P T
Sbjct: 8 LLCLALLPALAARGPRCSQPGETCLNGGKCEAANGTEACVCGGAFVGPRC-QDPNPCLST 66
Query: 56 PTCAPRNATSVDS-GAPGGAAPGGPGFRAFLC--PLI-------CHNGGVC----VKPDR 101
P VD G A GF LC PL C NGG C + +
Sbjct: 67 PCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYK 126
Query: 102 CLCPPDFAGKFCQLHSSGARPPAPAVPGLTRSVYTMPLANHRDDEHGVASMVSVHVEHPQ 161
C CPP ++GK CQ A P A + P AN G + P
Sbjct: 127 CRCPPGWSGKSCQQ----ADPCA-----------SNPCAN------GGQCL-------PF 158
Query: 162 EASVVVHQVERVSGPWEEADAEAVARAEAAARAEAAAPYTVLAQSAPREDGYSDASGFGY 221
EAS + H GP D + R V +
Sbjct: 159 EASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRC-------------V 205
Query: 222 CFRELRGGECASPL----PGLRTQEVCCRGAGLAWGVHDC--------QLCSERLGNSER 269
C G C P P CR G H+C Q C E + +
Sbjct: 206 CRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDV--THECACLPGFTGQNCEENIDDCPG 263
Query: 270 VSAPDG-PCPTGFERVNGSC----------EDVDECAT-GGRCQHG-ECANTRGGYTCVC 316
+ +G C G N C EDVDEC CQ+G C NT GGY CVC
Sbjct: 264 NNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVC 323
Query: 317 PDGFLLDSSRSSCISQHVISEAKGPCFRV------LRDGGCSLPILRNITKQIC-----C 365
+G+ + C S+++ A CF + C P R T +C C
Sbjct: 324 VNGW----TGEDC-SENIDDCASAACFHGATCHDRVASFYCECPHGR--TGLLCHLNDAC 376
Query: 366 CSRVGKAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPR 425
S G C P G + IC GY A + LG P +
Sbjct: 377 ISNPCNE-GSNCDTNPVNG----KAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCIN 431
Query: 426 TLPATSRPSAGFLPTHRLEPRPEPR---------PDPRPGPELPLPSIPAWTGPEIPESG 476
TL G L+ PR +P L I + +P G
Sbjct: 432 TL--------GSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMP--G 481
Query: 477 PSSGMCQRNPQVCGP------GRCISRPSGYTCACDSGFRLSPQGTRC-IDVDECRRVPP 529
C+ N C GRC+ + + + C C +GF G C DVDEC P
Sbjct: 482 YEGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPTGFT----GHLCQYDVDECASTP- 536
Query: 530 PCAPG-RCENSPGSFRCVCGPGFRAGPRAAEC-LDVDECHRVPPPCDLGRCENTPGSFLC 587
C G +C + P ++ CVC G+ C +D+DEC P PC G C++ +F C
Sbjct: 537 -CKNGAKCLDGPNTYTCVCTEGYTG----THCEVDIDECD--PDPCHYGSCKDGVATFTC 589
Query: 588 VCPAGY--------------QAAPHGASCQD---------------------VDECTQSP 612
+C GY Q HG +CQD +D+C SP
Sbjct: 590 LCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSP 649
Query: 613 GLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPA 672
C G C + + C C G+ GS C ++DECA P G G C++ F C CP
Sbjct: 650 --CDSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNG-GTCEDGINGFTCRCPE 706
Query: 673 GFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECE-DVDEC 731
G+ +V+EC + PC +G C ++ ++C C P +G+ C+ + +EC
Sbjct: 707 GYHD---PTCLSEVNEC--NSNPCVHGACRDSLNGYKCDC----DPGWSGTNCDINNNEC 757
Query: 732 ENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRC-TDVDECSSGAPPCGPHGHCTNTEGS 790
E++ G C + + C TC G C T+++EC+S PC G C +
Sbjct: 758 ESNPCVNGGTCKDMTSGYVC-TCREG--FSGPNCQTNINECASN--PCLNQGTCIDDVAG 812
Query: 791 FRCSCAPGYRAPSGRP--GPCADVNECLEGDFCFPHGECLNTDG--SFACTCAPGYRPGP 846
++C+C Y + PCA + C G GEC ++ SF+C C G+
Sbjct: 813 YKCNCLLPYTGATCEVVLAPCAP-SPCRNG------GECRQSEDYESFSCVCPTGW---- 861
Query: 847 RGASC-LDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASC-LDVDECRERGPA 904
+G +C +D++EC C NT G + C C G+ +C D+D+CR
Sbjct: 862 QGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSG----RNCETDIDDCRPNPCH 917
Query: 905 LCGSQRCENSPGSYRCVRDCDPGYHAGPEGTC--DDVDECQEYGPEICGAQRCENTPGSY 962
GS C + + C DC PG+ GT +D++EC P GA C + SY
Sbjct: 918 NGGS--CTDGINTAFC--DCLPGF----RGTFCEEDINECAS-DPCRNGA-NCTDCVDSY 967
Query: 963 RCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHC 1022
CT C G+ G C++ S C C + SF CLC G+ G+ +C
Sbjct: 968 TCT--CPAGFS---GIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGS----YC 1018
Query: 1023 V-DVNECETLQGVCGAALCENVEGSFLCVCPN--SPEEFDPMTGRCVPPRTSAG-----T 1074
DVNEC++ Q C++ GS+ C CP + + C G T
Sbjct: 1019 QHDVNECDS-QPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQT 1077
Query: 1075 FPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNV 1134
+ + P S P + + RQG R C DA +
Sbjct: 1078 HTQYRCECP-SGWTGLYCDVPSVSCEVAAQRQGV--DVARLCQHGGLCVDAGNT------ 1128
Query: 1135 TWQECCCTVGEGWGSGCR--IQQCPGTETAEYQSLCPHGRGY----LAPSGDLSLRRDVD 1188
C C G GS C + +C + + + GY +A ++ ++D
Sbjct: 1129 --HHCRCQAGY-TGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEID 1185
Query: 1189 ECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLEC-IDNDEC------ADEEPAC- 1240
EC Q G C++ Y C C G TQ + C I+ D+C P C
Sbjct: 1186 ECLSHPCQ--NGGTCLDLPNTYKCSCPRG----TQGVHCEINVDDCNPPVDPVSRSPKCF 1239
Query: 1241 EGGRCVNTVGSYHCTCEPPLV---LDGSQRRCVSN 1272
G CV+ VG Y CTC P V +G C+SN
Sbjct: 1240 NNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSN 1274
Score = 270 bits (690), Expect = 8e-72
Identities = 305/1148 (26%), Positives = 429/1148 (37%), Gaps = 213/1148 (18%)
Query: 257 CQLCSERLGNSERVSAPDGP--CPTGFERVNGSCEDVDECATGGRCQHGEC--ANTRG-- 310
C E N + A +G C G V C+D + C + G C + RG
Sbjct: 24 CSQPGETCLNGGKCEAANGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGVA 83
Query: 311 GYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGG-CSLPILRNITKQICCCSRV 369
Y C C GF S C++ + PC R+GG C L L T+ C C
Sbjct: 84 DYACSCALGF----SGPLCLTPLDNACLTNPC----RNGGTCDLLTL---TEYKCRCP-- 130
Query: 370 GKAW-GRGCQLCPPFGSEGFRE-----------ICPAGPGYHYSASDLRYNTRPLGQEPP 417
W G+ CQ P S IC P +H R + GQ+P
Sbjct: 131 -PGWSGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSFH--GPTCRQDVNECGQKPG 187
Query: 418 ---------------RVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLP 462
R T P RP ++P P P G P
Sbjct: 188 LCRHGGTCHNEVGSYRCVCRATHTGPNCERP---YVPC-------SPSPCQNGGTCRPTG 237
Query: 463 SI-------PAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQG 515
+ P +TG E+ C N G G C+ + Y C C + G
Sbjct: 238 DVTHECACLPGFTGQNCEENIDD---CPGNNCKNG-GACVDGVNTYNCRCPPEWT----G 289
Query: 516 TRCI-DVDECRRVPPPCAPG-RCENSPGSFRCVCGPGFRAGP--------RAAECLDVDE 565
C DVDEC+ +P C G C N+ G + CVC G+ +A C
Sbjct: 290 QYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGAT 349
Query: 566 CHR------------------------VPPPCDLG-RCENTP--GSFLCVCPAGYQAAPH 598
CH + PC+ G C+ P G +C CP+GY
Sbjct: 350 CHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYT---- 405
Query: 599 GASC-QDVDECTQSPGLCGR-GACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGP 656
G +C QDVDEC+ C G C N GSF C C G+ G CE DV+EC P
Sbjct: 406 GPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQ-ND 464
Query: 657 GRCDNTAGSFHCACPAGFRSRGPGAPCQ-DVDECARSPPPCTY-GRCENTEGSFQCVCPM 714
C + G F C C G+ G C+ + DECA SP C + GRC + FQC CP
Sbjct: 465 ATCLDQIGEFQCICMPGYE----GVHCEVNTDECASSP--CLHNGRCLDKINEFQCECPT 518
Query: 715 GFQPNTAGSECE-DVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRC-TDVDECS 772
GF G C+ DVDEC + G +C++ P ++ C C G+ C D+DEC
Sbjct: 519 GF----TGHLCQYDVDECASTPCKNGAKCLDGPNTYTC-VCTEGYT--GTHCEVDIDECD 571
Query: 773 SGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDG 832
PC +G C + +F C C PGY ++NEC C G C + D
Sbjct: 572 PD--PCH-YGSCKDGVATFTCLCRPGYTGHHCE----TNINEC-SSQPCRHGGTCQDRDN 623
Query: 833 SFACTCAPGYRPGPRGASC-LDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLAS 891
++ C C G G +C +++D+C+ C SG C + +EC C PG+ +
Sbjct: 624 AYLCFCLKG----TTGPNCEINLDDCASSP-CDSGTCLDKIDGYECACEPGYTG----SM 674
Query: 892 C-LDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTC-DDVDECQEYGPEI 949
C +++DEC G CE+ + C C GYH + TC +V+EC P +
Sbjct: 675 CNINIDECA--GNPCHNGGTCEDGINGFTC--RCPEGYH---DPTCLSEVNECNS-NPCV 726
Query: 950 CGAQRCENTPGSYRCTPACDPGYQPTPGGGCQ-DVDECRNRSFCGAHAVCQNLPGSFQCL 1008
GA C ++ Y+C CDPG+ G C + +EC + C C+++ + C
Sbjct: 727 HGA--CRDSLNGYKCD--CDPGWS---GTNCDINNNECESNP-CVNGGTCKDMTSGYVCT 778
Query: 1009 CDQGYEGARDGRHC-VDVNECETLQGVCGAALCENVEG-SFLCVCPNSPEEFDPMTGRCV 1066
C +G+ G +C ++NEC + + ++V G C+ P + + + C
Sbjct: 779 CREGFSGP----NCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCA 834
Query: 1067 P-PRTSAGTFPGSQPQAPASPVLPARPPPPPL----------PRRPSTPRQGPVGSGRRE 1115
P P + G S+ S V P P R Q G R
Sbjct: 835 PSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCH 894
Query: 1116 CY-----------FDTAAPDACDN--ILARNVTWQECCCTVGEGWGSGCR--IQQCPGTE 1160
C D P+ C N + C C G G+ C I +C
Sbjct: 895 CQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFR-GTFCEEDINECASDP 953
Query: 1161 TAEYQSL--CPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGY 1218
+ C P+G + + + G CV+ ++C C G+
Sbjct: 954 CRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGF 1013
Query: 1219 YYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLD 1278
T D +EC D +P GG C + GSY CTC P + + V S
Sbjct: 1014 ---TGSYCQHDVNEC-DSQPCLHGGTCQDGCGSYRCTC-PQGYTGPNCQNLVHWCDSSPC 1068
Query: 1279 DNLGVCWQ 1286
N G CWQ
Sbjct: 1069 KNGGKCWQ 1076
Score = 246 bits (628), Expect = 1e-64
Identities = 271/953 (28%), Positives = 366/953 (38%), Gaps = 178/953 (18%)
Query: 457 PELPLPSIPAWTGPEIPESGPSSGMCQRNPQVC-GPGRCISRPSGYTCACDSGFRLSPQG 515
P L P + P + GP C + + C G+C + C C F G
Sbjct: 2 PPLLAPLLCLALLPALAARGPR---CSQPGETCLNGGKCEAANGTEACVCGGAF----VG 54
Query: 516 TRCIDVDECRRVPPPCAPGRCE----NSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPP 571
RC D + C P A G C + C C GF +GP LD + C +
Sbjct: 55 PRCQDPNPCLSTPCKNA-GTCHVVDRRGVADYACSCALGF-SGPLCLTPLD-NAC--LTN 109
Query: 572 PC-DLGRCEN-TPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRC 629
PC + G C+ T + C CP G+ G SCQ D C +P G G C S+ C
Sbjct: 110 PCRNGGTCDLLTLTEYKCRCPPGWS----GKSCQQADPCASNPCANG-GQCLPFEASYIC 164
Query: 630 VCPAGFRGSACEEDVDECAQEPPPCGPG-RCDNTAGSFHCACPA---GFRSRGPGAPCQD 685
CP F G C +DV+EC Q+P C G C N GS+ C C A G P PC
Sbjct: 165 HCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPC-- 222
Query: 686 VDECARSPPPCTYG-RCENT-EGSFQCVCPMGFQPNTAGSECED-VDECENHLACPGQEC 742
SP PC G C T + + +C C GF G CE+ +D+C + G C
Sbjct: 223 ------SPSPCQNGGTCRPTGDVTHECACLPGF----TGQNCEENIDDCPGNNCKNGGAC 272
Query: 743 VNSPGSFQCRTCPSGHHLHRGRCT-DVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGY-- 799
V+ ++ CR P + CT DVDEC C G C NT G + C C G+
Sbjct: 273 VDGVNTYNCRCPPEWTGQY---CTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTG 329
Query: 800 ------------------------------RAPSGRPGPCADVNECLEGDFCFPHGECLN 829
P GR G +N+ + C C
Sbjct: 330 EDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDT 389
Query: 830 T--DGSFACTCAPGYRPGPRGASCLDVDECS-EEDLCQ-SGICTNTDGSFECICPPGHRA 885
+G CTC GY GP A DVDECS + C+ +G C NT GSFEC C G+
Sbjct: 390 NPVNGKAICTCPSGYT-GP--ACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGY-T 445
Query: 886 GPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGT-CD-DVDECQ 943
GP +DV+EC C + G ++C+ C PGY EG C+ + DEC
Sbjct: 446 GPRCE--IDVNECVSN--PCQNDATCLDQIGEFQCI--CMPGY----EGVHCEVNTDECA 495
Query: 944 EYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQ-DVDECRNRSFCGAHAVCQNLP 1002
P + RC + ++C C G+ G CQ DVDEC + C A C + P
Sbjct: 496 S-SPCLHNG-RCLDKINEFQCE--CPTGFT---GHLCQYDVDECASTP-CKNGAKCLDGP 547
Query: 1003 GSFQCLCDQGYEGARDGRHC-VDVNECETLQGVCGAALCENVEGSFLCVCPN--SPEEFD 1059
++ C+C +GY G HC VD++EC+ C C++ +F C+C + +
Sbjct: 548 NTYTCVCTEGYTGT----HCEVDIDECDP--DPCHYGSCKDGVATFTCLCRPGYTGHHCE 601
Query: 1060 PMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFD 1119
C G + A L P E D
Sbjct: 602 TNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGP------------------NCEINLD 643
Query: 1120 TAAPDACDN-ILARNVTWQECCCTVGEGWGSGCRIQ--QCPGTETAEYQSLCPHG-RGYL 1175
A CD+ + EC C G GS C I +C G C G G+
Sbjct: 644 DCASSPCDSGTCLDKIDGYECACEPGYT-GSMCNINIDECAGNP-CHNGGTCEDGINGFT 701
Query: 1176 A--PSG--DLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLEC-IDN 1230
P G D + +V+EC C G C ++ GY C C G+ C I+N
Sbjct: 702 CRCPEGYHDPTCLSEVNECN---SNPCVHGACRDSLNGYKCDCDPGW----SGTNCDINN 754
Query: 1231 DECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDD---NLGVCWQE 1287
+EC + P GG C + Y CTC S C +N ++ + N G C +
Sbjct: 755 NEC-ESNPCVNGGTCKDMTSGYVCTCREGF----SGPNCQTNINECASNPCLNQGTCIDD 809
Query: 1288 V-GADLVCSHPRLDRQATYTECCCLYGEAWGMDCALCPAQD------SDDFEA 1333
V G C P YT C E CA P ++ S+D+E+
Sbjct: 810 VAGYKCNCLLP-------YTGATC---EVVLAPCAPSPCRNGGECRQSEDYES 852
Score = 228 bits (582), Expect = 3e-59
Identities = 200/625 (32%), Positives = 270/625 (43%), Gaps = 110/625 (17%)
Query: 465 PAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRC-IDVDE 523
P W+G + + C+ NP V G G C SGY C C GF G C +++E
Sbjct: 743 PGWSGTNCDIN---NNECESNPCVNG-GTCKDMTSGYVCTCREGF----SGPNCQTNINE 794
Query: 524 CRRVPPPCA-PGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPC-DLGRCENT 581
C PC G C + ++C C P +V P PC + G C +
Sbjct: 795 C--ASNPCLNQGTCIDDVAGYKCNC-----LLPYTGATCEVVLAPCAPSPCRNGGECRQS 847
Query: 582 PG--SFLCVCPAGYQAAPHGASCQ-DVDECTQSPGLCGRGA-CKNLPGSFRCVCPAGFRG 637
SF CVCP G+Q G +C+ D++EC SP C GA C+N G +RC C AG+ G
Sbjct: 848 EDYESFSCVCPTGWQ----GQTCEVDINECVLSP--CRHGASCQNTHGGYRCHCQAGYSG 901
Query: 638 SACEEDVDECAQEPPPC-GPGRCDNTAGSFHCACPAGFRSRGPGAPC-QDVDECARSPPP 695
CE D+D+C P PC G C + + C C GFR G C +D++ECA P
Sbjct: 902 RNCETDIDDC--RPNPCHNGGSCTDGINTAFCDCLPGFR----GTFCEEDINECASD--P 953
Query: 696 CTYG-RCENTEGSFQCVCPMGFQPNTAGSECE-DVDECENHLACPGQECVNSPGSFQCRT 753
C G C + S+ C CP GF +G CE + +C G CV+ SF C
Sbjct: 954 CRNGANCTDCVDSYTCTCPAGF----SGIHCENNTPDCTESSCFNGGTCVDGINSFTC-L 1008
Query: 754 CPSGHHLHRGRCT-DVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADV 812
CP G C DV+EC S PC G C + GS+RC+C GY P+ C ++
Sbjct: 1009 CPPG--FTGSYCQHDVNECDS--QPCLHGGTCQDGCGSYRCTCPQGYTGPN-----CQNL 1059
Query: 813 NECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEE-----------D 861
+ C G+C T + C C G+ G C DV S E
Sbjct: 1060 VHWCDSSPCKNGGKCWQTHTQYRCECPSGW----TGLYC-DVPSVSCEVAAQRQGVDVAR 1114
Query: 862 LCQ-SGICTNTDGSFECICPPGHRAGPDLASCLD-VDECRERGPALC-GSQRCENSPGSY 918
LCQ G+C + + C C G+ + C D VDEC P+ C C + G Y
Sbjct: 1115 LCQHGGLCVDAGNTHHCRCQAGYTG----SYCEDLVDEC---SPSPCQNGATCTDYLGGY 1167
Query: 919 RCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGG 978
C C GYH +++DEC + + G C + P +Y+C +C G T G
Sbjct: 1168 SC--KCVAGYHG--VNCSEEIDECLSHPCQNGGT--CLDLPNTYKC--SCPRG---TQGV 1216
Query: 979 GCQ-DVDECR------NRS-FCGAHAVCQNLPGSFQCLCDQGYEGAR-DGRHCVDVNECE 1029
C+ +VD+C +RS C + C + G + C C G+ G R +G DVNEC
Sbjct: 1217 HCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEG----DVNEC- 1271
Query: 1030 TLQGVC---GAALCENVEGSFLCVC 1051
L C G C F C C
Sbjct: 1272 -LSNPCDARGTQNCVQRVNDFHCEC 1295
Score = 209 bits (532), Expect = 2e-53
Identities = 187/625 (29%), Positives = 256/625 (40%), Gaps = 138/625 (22%)
Query: 494 CISRPSGYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCAPG-RCENSPGSFRCVCGPGF 551
C + GY C C +G+ G C D+D+CR P PC G C + + C C PGF
Sbjct: 884 CQNTHGGYRCHCQAGY----SGRNCETDIDDCR--PNPCHNGGSCTDGINTAFCDCLPGF 937
Query: 552 RAGPRAAECLDVDECHRVPPPCDLG-RCENTPGSFLCVCPAGYQAAPHGASCQD-VDECT 609
R G E D++EC PC G C + S+ C CPAG+ G C++ +CT
Sbjct: 938 R-GTFCEE--DINEC--ASDPCRNGANCTDCVDSYTCTCPAGFS----GIHCENNTPDCT 988
Query: 610 QSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCA 669
+S G G C + SF C+CP GF GS C+ DV+EC +P G G C + GS+ C
Sbjct: 989 ESSCFNG-GTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHG-GTCQDGCGSYRCT 1046
Query: 670 CPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQP---NTAGSECE 726
CP G+ G CQ++ S P G+C T ++C CP G+ + CE
Sbjct: 1047 CPQGY----TGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCE 1102
Query: 727 DVDECEN----HLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTD-VDECSSGAPPCGPH 781
+ + L G CV++ + CR C +G+ C D VDECS PC
Sbjct: 1103 VAAQRQGVDVARLCQHGGLCVDAGNTHHCR-CQAGY--TGSYCEDLVDECSPS--PCQNG 1157
Query: 782 GHCTNTEGSFRCSCAPGYRAPSGRPGPCA-DVNECLEGDFCFPHGECLNTDGSFACTCAP 840
CT+ G + C C GY + C+ +++ECL C G CL+ ++ C+C
Sbjct: 1158 ATCTDYLGGYSCKCVAGYHGVN-----CSEEIDECLSHP-CQNGGTCLDLPNTYKCSCP- 1210
Query: 841 GYRPGPRGASC-LDVDEC-------SEEDLC-QSGICTNTDGSFECICPP---GHRAGPD 888
G +G C ++VD+C S C +G C + G + C CPP G R D
Sbjct: 1211 ---RGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGD 1267
Query: 889 LASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPE 948
+ CL + C R G+Q C + C +C G H G
Sbjct: 1268 VNECLS-NPCDAR-----GTQNCVQRVNDFHC--ECRAG-HTG----------------- 1301
Query: 949 ICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCL 1008
+RCE+ + P C+N C AV N F C
Sbjct: 1302 ----RRCESVINGCKGKP-------------------CKNGGTC---AVASNTARGFICK 1335
Query: 1009 CDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPP 1068
C G+EGA CE CG+ C N G P SP T C+
Sbjct: 1336 CPAGFEGA----------TCENDARTCGSLRCLN--GGTCISGPRSP------TCLCL-- 1375
Query: 1069 RTSAGTFPGSQPQAPA-SPVLPARP 1092
G F G + Q PA SP L P
Sbjct: 1376 ----GPFTGPECQFPASSPCLGGNP 1396
Score = 176 bits (446), Expect = 2e-43
Identities = 229/926 (24%), Positives = 329/926 (35%), Gaps = 193/926 (20%)
Query: 260 CSERLGNSERVSAPDGPCPTGFERVNGSCEDVDECATGGRCQHGECANTRGGYTCVCPDG 319
C + L N + G T + N CE + C GG C+ + GY C C +G
Sbjct: 730 CRDSL-NGYKCDCDPGWSGTNCDINNNECES-NPCVNGGTCK-----DMTSGYVCTCREG 782
Query: 320 FL---LDSSRSSCISQHVISEAKGPCFRVLRDGGCS--LPILRNITKQICC-CSRVGKAW 373
F ++ + C S +++ G C + C+ LP + + C+
Sbjct: 783 FSGPNCQTNINECASNPCLNQ--GTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRN 840
Query: 374 GRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPA-TSR 432
G C+ + E F +CP G + + P R S T
Sbjct: 841 GGECRQSEDY--ESFSCVCPTG----WQGQTCEVDINECVLSPCRHGASCQNTHGGYRCH 894
Query: 433 PSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGP- 491
AG+ + + RP+P I +P G C+ + C
Sbjct: 895 CQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLP--GFRGTFCEEDINECASD 952
Query: 492 -----GRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAP------GRCENSP 540
C YTC C +GF C P C G C +
Sbjct: 953 PCRNGANCTDCVDSYTCTCPAGF----------SGIHCENNTPDCTESSCFNGGTCVDGI 1002
Query: 541 GSFRCVCGPGFRAGPRAAECL-DVDECHRVPPPC-DLGRCENTPGSFLCVCPAGYQAAPH 598
SF C+C PGF + C DV+EC PC G C++ GS+ C CP GY
Sbjct: 1003 NSFTCLCPPGFTG----SYCQHDVNECDS--QPCLHGGTCQDGCGSYRCTCPQGYT---- 1052
Query: 599 GASCQD-VDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGP- 656
G +CQ+ V C SP G G C +RC CP+G+ G C+ C G
Sbjct: 1053 GPNCQNLVHWCDSSPCKNG-GKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVD 1111
Query: 657 --------GRCDNTAGSFHCACPAGFRSRGPGAPCQD-VDECARSPPPCTYGR-CENTEG 706
G C + + HC C AG+ G+ C+D VDEC SP PC G C + G
Sbjct: 1112 VARLCQHGGLCVDAGNTHHCRCQAGYT----GSYCEDLVDEC--SPSPCQNGATCTDYLG 1165
Query: 707 SFQCVCPMGFQPNTAGSEC-EDVDECENHLACPGQECVNSPGSFQCRTCPSGHH-LHRGR 764
+ C C G+ G C E++DEC +H G C++ P +++C +CP G +H
Sbjct: 1166 GYSCKCVAGYH----GVNCSEEIDECLSHPCQNGGTCLDLPNTYKC-SCPRGTQGVH--- 1217
Query: 765 CT-DVDECS------SGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLE 817
C +VD+C+ S +P C +G C + G + C+C PG+ DVNECL
Sbjct: 1218 CEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCE----GDVNECLS 1273
Query: 818 GDFCFPHG--ECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSG----ICTNT 871
C G C+ F C C R G G C V + C++G + +NT
Sbjct: 1274 NP-CDARGTQNCVQRVNDFHCEC----RAGHTGRRCESVINGCKGKPCKNGGTCAVASNT 1328
Query: 872 DGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENS------PGSYRCV---- 921
F C CP G A+C E CGS RC N P S C+
Sbjct: 1329 ARGFICKCPAGFEG----ATC-------ENDARTCGSLRCLNGGTCISGPRSPTCLCLGP 1377
Query: 922 -----------RDCDPGYHAGPEGTCDDVDECQEYG------------------------ 946
C G +GTC+ E Y
Sbjct: 1378 FTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAG 1437
Query: 947 --------PEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVC 998
E C C+ G+ C+ C+ GG C +
Sbjct: 1438 RDIPPPLIEEACELPECQEDAGNKVCSLQCNNHACGWDGGDCS----------LNFNDPW 1487
Query: 999 QNLPGSFQC---LCDQGYEGARDGRHCV-DVNECETLQGVCGA---ALCENVEGSFLC-- 1049
+N S QC D + + C+ D +C+ +G C C++ C
Sbjct: 1488 KNCTQSLQCWKYFSDGHCDSQCNSAGCLFDGFDCQRAEGQCNPLYDQYCKDHFSDGHCDQ 1547
Query: 1050 VCPNSPEEFDPM-TGRCVPPRTSAGT 1074
C ++ E+D + VP R +AGT
Sbjct: 1548 GCNSAECEWDGLDCAEHVPERLAAGT 1573
Score = 52.8 bits (125), Expect = 3e-06
Identities = 28/83 (33%), Positives = 44/83 (53%), Gaps = 11/83 (13%)
Query: 1466 EAEECGI-LDGCTN-GRCVRVPEGFTCRCFDGYRLDMTRMAC-VDINECDEAEAASPLCV 1522
+ +EC + + C + G+C+ F C+C GY T C +D+NEC ++P
Sbjct: 412 DVDECSLGANPCEHAGKCINTLGSFECQCLQGY----TGPRCEIDVNEC----VSNPCQN 463
Query: 1523 NARCLNTDGSFRCICRPGFAPTH 1545
+A CL+ G F+CIC PG+ H
Sbjct: 464 DATCLDQIGEFQCICMPGYEGVH 486
Score = 49.7 bits (117), Expect = 2e-05
Identities = 31/89 (34%), Positives = 43/89 (48%), Gaps = 16/89 (17%)
Query: 1464 ELEAEECGILDGCTNG-RCVRVPEGFTCRCFDGYRLDMTRMAC-VDINECDEAEAASPLC 1521
+ + +EC C NG +C+ P +TC C +GY T C VDI+ECD C
Sbjct: 526 QYDVDECASTP-CKNGAKCLDGPNTYTCVCTEGY----TGTHCEVDIDECDPDP-----C 575
Query: 1522 VNARCLNTDGSFRCICRPGFAPTHQPHHC 1550
C + +F C+CRPG+ HHC
Sbjct: 576 HYGSCKDGVATFTCLCRPGYT----GHHC 600
Score = 47.4 bits (111), Expect = 1e-04
Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 7/82 (8%)
Query: 1464 ELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 1523
E+ +EC NGRC+ F C C G+ + + D++EC A++P
Sbjct: 488 EVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQY---DVDEC----ASTPCKNG 540
Query: 1524 ARCLNTDGSFRCICRPGFAPTH 1545
A+CL+ ++ C+C G+ TH
Sbjct: 541 AKCLDGPNTYTCVCTEGYTGTH 562
Score = 47.0 bits (110), Expect = 1e-04
Identities = 29/92 (31%), Positives = 46/92 (50%), Gaps = 12/92 (13%)
Query: 1454 YAGSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDE 1513
Y GS+ + +EC G C GFTCRC +GY D T ++ ++NEC+
Sbjct: 670 YTGSMCN----INIDECAGNPCHNGGTCEDGINGFTCRCPEGYH-DPTCLS--EVNECN- 721
Query: 1514 AEAASPLCVNARCLNTDGSFRCICRPGFAPTH 1545
S CV+ C ++ ++C C PG++ T+
Sbjct: 722 ----SNPCVHGACRDSLNGYKCDCDPGWSGTN 749
Score = 40.4 bits (93), Expect = 0.013
Identities = 26/70 (37%), Positives = 33/70 (47%), Gaps = 10/70 (14%)
Query: 1476 CTNGRCVRVPE---GFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGS 1532
C NG R E F+C C G++ VDINEC SP A C NT G
Sbjct: 838 CRNGGECRQSEDYESFSCVCPTGWQGQTCE---VDINEC----VLSPCRHGASCQNTHGG 890
Query: 1533 FRCICRPGFA 1542
+RC C+ G++
Sbjct: 891 YRCHCQAGYS 900
Score = 39.7 bits (91), Expect = 0.023
Identities = 24/78 (30%), Positives = 36/78 (46%), Gaps = 3/78 (3%)
Query: 1466 EAEECGILDGCTNG-RCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN- 1523
E +EC + C NG C+ +P + C C G + + D N + + SP C N
Sbjct: 1183 EIDEC-LSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNN 1241
Query: 1524 ARCLNTDGSFRCICRPGF 1541
C++ G + C C PGF
Sbjct: 1242 GTCVDQVGGYSCTCPPGF 1259
Score = 38.5 bits (88), Expect = 0.051
Identities = 25/68 (36%), Positives = 31/68 (45%), Gaps = 10/68 (14%)
Query: 1476 CTNG-RCVRVPEGFTCRCFDGYRLDMTRMACV-DINECDEAEAASPLCVNARCLNTDGSF 1533
C NG CV FTC C G+ T C D+NECD + P C + GS+
Sbjct: 992 CFNGGTCVDGINSFTCLCPPGF----TGSYCQHDVNECD----SQPCLHGGTCQDGCGSY 1043
Query: 1534 RCICRPGF 1541
RC C G+
Sbjct: 1044 RCTCPQGY 1051
Score = 38.1 bits (87), Expect = 0.067
Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 11/86 (12%)
Query: 1466 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA- 1524
+A+ C G+C+ + C C + R D+NEC + LC +
Sbjct: 140 QADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQ---DVNECGQKPG---LCRHGG 193
Query: 1525 RCLNTDGSFRCICRPGFAPTHQPHHC 1550
C N GS+RC+CR TH +C
Sbjct: 194 TCHNEVGSYRCVCR----ATHTGPNC 215
Score = 37.4 bits (85), Expect = 0.11
Identities = 28/92 (30%), Positives = 39/92 (42%), Gaps = 21/92 (22%)
Query: 1464 ELEAEECGILDGCTNG-RCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCV 1522
E + EC D C NG C + +TC C G+ + + C E +P C
Sbjct: 943 EEDINECAS-DPCRNGANCTDCVDSYTCTCPAGF----SGIHC---------ENNTPDCT 988
Query: 1523 NARCLN----TDG--SFRCICRPGFAPTHQPH 1548
+ C N DG SF C+C PGF ++ H
Sbjct: 989 ESSCFNGGTCVDGINSFTCLCPPGFTGSYCQH 1020
Score = 33.9 bits (76), Expect = 1.3
Identities = 24/79 (30%), Positives = 35/79 (44%), Gaps = 12/79 (15%)
Query: 1466 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMAC-VDINECDEAEAASPLCVNA 1524
E EC + C +G C G+ C C G+ + C ++ NEC+ S CVN
Sbjct: 716 EVNECNS-NPCVHGACRDSLNGYKCDCDPGW----SGTNCDINNNECE-----SNPCVNG 765
Query: 1525 -RCLNTDGSFRCICRPGFA 1542
C + + C CR GF+
Sbjct: 766 GTCKDMTSGYVCTCREGFS 784
Score = 33.5 bits (75), Expect = 1.6
Identities = 32/106 (30%), Positives = 40/106 (37%), Gaps = 13/106 (12%)
Query: 41 CG-LRCVHGPTGSRCTPTCAPRNATSVDSGAPGGAAPGGPGFRAFLCPLICHNGGVCVKP 99
CG LRC++G T C PR+ T + G G P L C+N G C
Sbjct: 1352 CGSLRCLNGGT---CIS--GPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPT 1406
Query: 100 D-----RCLCPPDFAGKFCQL--HSSGARPPAPAVPGLTRSVYTMP 138
RCLCP F G C + +S G P L +P
Sbjct: 1407 SESPFYRCLCPAKFNGLLCHILDYSFGGGAGRDIPPPLIEEACELP 1452
Score = 33.1 bits (74), Expect = 2.1
Identities = 21/70 (30%), Positives = 30/70 (42%), Gaps = 8/70 (11%)
Query: 1474 DGCTNG-RCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA-RCLNTDG 1531
+ C NG CV + CRC + T C + + DE + C N C NT G
Sbjct: 264 NNCKNGGACVDGVNTYNCRCPP----EWTGQYCTE--DVDECQLMPNACQNGGTCHNTHG 317
Query: 1532 SFRCICRPGF 1541
+ C+C G+
Sbjct: 318 GYNCVCVNGW 327
Score = 33.1 bits (74), Expect = 2.1
Identities = 24/82 (29%), Positives = 34/82 (41%), Gaps = 9/82 (10%)
Query: 1464 ELEAEECGILDGCTNGR-CVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCV 1522
E++ EC +L C +G C G+ C C GY R DI++C +P
Sbjct: 867 EVDINEC-VLSPCRHGASCQNTHGGYRCHCQAGY---SGRNCETDIDDC----RPNPCHN 918
Query: 1523 NARCLNTDGSFRCICRPGFAPT 1544
C + + C C PGF T
Sbjct: 919 GGSCTDGINTAFCDCLPGFRGT 940
Score = 32.3 bits (72), Expect = 3.7
Identities = 28/112 (25%), Positives = 37/112 (33%), Gaps = 39/112 (34%)
Query: 1464 ELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMAC-VDINECDEA-------- 1514
E++ +EC D C G C FTC C GY T C +INEC
Sbjct: 564 EVDIDECDP-DPCHYGSCKDGVATFTCLCRPGY----TGHHCETNINECSSQPCRHGGTC 618
Query: 1515 -------------------------EAASPLCVNARCLNTDGSFRCICRPGF 1541
+ AS C + CL+ + C C PG+
Sbjct: 619 QDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGY 670
Score = 32.3 bits (72), Expect = 3.7
Identities = 31/107 (28%), Positives = 40/107 (37%), Gaps = 14/107 (13%)
Query: 220 GYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDC--QLCSERLGNSERVSAPDGPC 277
G C ++ G C P PG + C G V++C C R + D C
Sbjct: 1242 GTCVDQVGGYSCTCP-PGFVGER--CEG-----DVNECLSNPCDARGTQNCVQRVNDFHC 1293
Query: 278 PTGFERVNGSCEDVDECATGGRCQHG-ECA---NTRGGYTCVCPDGF 320
CE V G C++G CA NT G+ C CP GF
Sbjct: 1294 ECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGF 1340
Score = 32.0 bits (71), Expect = 4.8
Identities = 17/74 (22%), Positives = 31/74 (41%), Gaps = 7/74 (9%)
Query: 1464 ELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 1523
++ EC G C + G+ C C +G+ + +INEC A++P
Sbjct: 751 DINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQ---TNINEC----ASNPCLNQ 803
Query: 1524 ARCLNTDGSFRCIC 1537
C++ ++C C
Sbjct: 804 GTCIDDVAGYKCNC 817
Score = 32.0 bits (71), Expect = 4.8
Identities = 26/94 (27%), Positives = 38/94 (40%), Gaps = 15/94 (15%)
Query: 1454 YAGSLAEPYEELEAEECGILDGCTNGR-CVRVPEGFTCRCFDGYRLDMTRMAC-VDINEC 1511
Y GS E +EC C NG C G++C+C GY + C +I+EC
Sbjct: 1137 YTGSYCEDL----VDECSP-SPCQNGATCTDYLGGYSCKCVAGYH----GVNCSEEIDEC 1187
Query: 1512 DEAEAASPLCVNARCLNTDGSFRCICRPGFAPTH 1545
+ P CL+ +++C C G H
Sbjct: 1188 ----LSHPCQNGGTCLDLPNTYKCSCPRGTQGVH 1217
>gi|24041035 notch 2 preproprotein [Homo sapiens]
Length = 2471
Score = 268 bits (686), Expect = 2e-71
Identities = 247/857 (28%), Positives = 331/857 (38%), Gaps = 183/857 (21%)
Query: 501 YTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGR-CENSPGSFRCVCGPGFRAGPRAAE 559
Y C C GF G C D C + PCA G C F C C GF +
Sbjct: 129 YECTCQVGFT----GKECQWTDAC--LSHPCANGSTCTTVANQFSCKCLTGFTG----QK 178
Query: 560 C-LDVDECHRVPPPCDLG-RCENTPGSFLCVCPAGYQAAPHGASCQDVD-ECTQSPGLCG 616
C DV+EC +P C G C N PGS+ C CP G+ G C + C SP + G
Sbjct: 179 CETDVNECD-IPGHCQHGGTCLNLPGSYQCQCPQGFT----GQYCDSLYVPCAPSPCVNG 233
Query: 617 RGACKNLPG-SFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFR 675
G C+ +F C C GF GS CE ++D+C G G C + +++C CP +
Sbjct: 234 -GTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNG-GVCVDGVNTYNCRCPPQWT 291
Query: 676 SRGPGAPC-QDVDECARSPPPCTYG-RCENTEGSFQCVCPMGFQPNTAGSEC-EDVDECE 732
G C +DVDEC P C G C N G + CVC G+ +G +C E++D+C
Sbjct: 292 ----GQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGW----SGDDCSENIDDCA 343
Query: 733 NHLACPGQECVNSPGSFQCRTCPSGH-----HL---------HRGR-------------- 764
PG C++ SF C CP G HL H+G
Sbjct: 344 FASCTPGSTCIDRVASFSCM-CPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICT 402
Query: 765 ---------CT-DVDECS-SGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVN 813
CT DVDEC+ + + PC G C NT+G+F C C GY P D+N
Sbjct: 403 CPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCE----MDIN 458
Query: 814 ECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASC-LDVDECSEEDLCQSGICTNTD 872
EC D C CL+ G F C C PG++ G C L+++EC +G C +
Sbjct: 459 EC-HSDPCQNDATCLDKIGGFTCLCMPGFK----GVHCELEINECQSNPCVNNGQCVDKV 513
Query: 873 GSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRC------------ 920
F+C+CPPG GP +D+D+C P L G+ +C + P Y C
Sbjct: 514 NRFQCLCPPGF-TGP--VCQIDIDDCSST-PCLNGA-KCIDHPNGYECQCATGFTGVLCE 568
Query: 921 --VRDCDPG--YHAGPEG-----TC------------DDVDECQEYGPEICGAQRCENTP 959
+ +CDP +H + TC D +DEC Y RC +
Sbjct: 569 ENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDEC--YSSPCLNDGRCIDLV 626
Query: 960 GSYRCTPACDPGYQPTPGGGCQ-DVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARD 1018
Y+C C PG T G C+ + D+C + H +C + + C+C G+ G R
Sbjct: 627 NGYQCN--CQPG---TSGVNCEINFDDCASNPCI--HGICMDGINRYSCVCSPGFTGQRC 679
Query: 1019 GRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFD--PMTGRCVPPRTSAGTFP 1076
+D++EC + GA V G F C+CP P C+ G
Sbjct: 680 N---IDIDECASNPCRKGATCINGVNG-FRCICPEGPHHPSCYSQVNECLSNPCIHGNCT 735
Query: 1077 GSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSG----RRECYFDTAA-PDACDNILA 1131
G L G VG + EC + CDN+
Sbjct: 736 GG------------------LSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNL-- 775
Query: 1132 RNVTWQECCCTVG-EGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDEC 1190
V C C G +G+ I +C + GY L C
Sbjct: 776 --VNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTC---HCVLPYTGKNC 830
Query: 1191 QLFRDQVCKSGVCVNTA--------PGYSCYCSNGYYYHTQRLEC-IDNDECADEEPACE 1241
Q C C N A Y+C C+ G+ Q C ID DEC +P
Sbjct: 831 QTVL-APCSPNPCENAAVCKESPNFESYTCLCAPGW----QGQRCTIDIDECI-SKPCMN 884
Query: 1242 GGRCVNTVGSYHCTCEP 1258
G C NT GSY C C P
Sbjct: 885 HGLCHNTQGSYMCECPP 901
Score = 262 bits (670), Expect = 2e-69
Identities = 301/1120 (26%), Positives = 432/1120 (38%), Gaps = 235/1120 (20%)
Query: 275 GPCPTGFERVNGSC----------EDVDECATG-GRCQHG-ECANTRGGYTCVCPDGFLL 322
G C G N C EDVDEC CQ+G CAN GGY CVC +G+
Sbjct: 273 GVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGW-- 330
Query: 323 DSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPP 382
S C S+++ A C G + + + + C C GKA G C L
Sbjct: 331 --SGDDC-SENIDDCAFASC----TPGSTCIDRVASFS---CMCPE-GKA-GLLCHLDDA 378
Query: 383 FGSEGFRE--ICPAGP--GYHYSASDLRYNTRPLGQEPPRVSL--SQPRTLPATSRPSAG 436
S + +C P G + Y ++ ++ S P + G
Sbjct: 379 CISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDG 438
Query: 437 FLPTHRLEPRPEPR---------PDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQ 487
L+ PR DP L I +T +P G C+
Sbjct: 439 AFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMP--GFKGVHCELEIN 496
Query: 488 VCGPGRCIS------RPSGYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCAPG-RCENS 539
C C++ + + + C C GF G C ID+D+C PC G +C +
Sbjct: 497 ECQSNPCVNNGQCVDKVNRFQCLCPPGF----TGPVCQIDIDDCSST--PCLNGAKCIDH 550
Query: 540 PGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHG 599
P + C C GF G E ++D C P PC G+C++ S+ C+C GY G
Sbjct: 551 PNGYECQCATGF-TGVLCEE--NIDNCD--PDPCHHGQCQDGIDSYTCICNPGYM----G 601
Query: 600 ASCQD-VDECTQSPGL------------------------------------CGRGACKN 622
A C D +DEC SP L C G C +
Sbjct: 602 AICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMD 661
Query: 623 LPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPG-RCDNTAGSFHCACPAGFRSRGPGA 681
+ CVC GF G C D+DECA PC G C N F C CP GP
Sbjct: 662 GINRYSCVCSPGFTGQRCNIDIDECASN--PCRKGATCINGVNGFRCICP-----EGPHH 714
Query: 682 PC--QDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECE-DVDECENHLACP 738
P V+EC + PC +G C ++C+C G+ G CE D +EC ++
Sbjct: 715 PSCYSQVNECLSN--PCIHGNCTGGLSGYKCLCDAGW----VGINCEVDKNECLSNPCQN 768
Query: 739 GQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPG 798
G C N ++C TC G + + ++DEC+S PC G C + + C C
Sbjct: 769 GGTCDNLVNGYRC-TCKKGFKGYNCQ-VNIDECASN--PCLNQGTCFDDISGYTCHCVLP 824
Query: 799 YRAPSGR-------PGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASC 851
Y + + P PC + C E P+ E S+ C CAPG+ +G C
Sbjct: 825 YTGKNCQTVLAPCSPNPCENAAVCKES----PNFE------SYTCLCAPGW----QGQRC 870
Query: 852 -LDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQR 910
+D+DEC + G+C NT GS+ C CPPG +G D D+D+C GS
Sbjct: 871 TIDIDECISKPCMNHGLCHNTQGSYMCECPPGF-SGMDCEE--DIDDCLANPCQNGGS-- 925
Query: 911 CENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEIC-GAQRCENTPGSYRCTPACD 969
C + ++ C+ C PG+ T D++EC E C C + SY C C
Sbjct: 926 CMDGVNTFSCL--CLPGFTGDKCQT--DMNECLS---EPCKNGGTCSDYVNSYTC--KCQ 976
Query: 970 PGYQPTPGGGCQ-DVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCV-DVNE 1027
G+ G C+ +++EC S C C + SF CLC G+ G+ C+ ++NE
Sbjct: 977 AGFD---GVHCENNINEC-TESSCFNGGTCVDGINSFSCLCPVGFTGS----FCLHEINE 1028
Query: 1028 CETLQGVCGAALCENVEGSFLCVCP--NSPEEFDPMTGRCV-PPRTSAGTFPGSQPQAPA 1084
C + C + G++ C CP + + + C P + GT Q +A +
Sbjct: 1029 CSS-HPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTC--VQKKAES 1085
Query: 1085 SPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILA--RNVTWQECCCT 1142
+ P SG Y D P+ +I A R V + C
Sbjct: 1086 QCLCP---------------------SGWAGAYCD--VPNVSCDIAASRRGVLVEHLCQH 1122
Query: 1143 VGEGWGSG-CRIQQCPGTETAEY---------QSLCPHGR-------GY----LAPSGDL 1181
G +G QCP T Y + C HG GY + +
Sbjct: 1123 SGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGV 1182
Query: 1182 SLRRDVDECQLFRDQVCKS-GVCVNTAPGYSCYCSNGYYYHTQRLECIDN-DECADEEPA 1239
+ +VDECQ +Q C++ G C++ + C C G T+ L C +N D+CA
Sbjct: 1183 NCEYEVDECQ---NQPCQNGGTCIDLVNHFKCSCPPG----TRGLLCEENIDDCARGPHC 1235
Query: 1240 CEGGRCVNTVGSYHCTCEPPLV---LDGSQRRCVSNESQS 1276
GG+C++ +G Y C C P +G C+SN S
Sbjct: 1236 LNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSS 1275
Score = 245 bits (626), Expect = 2e-64
Identities = 236/876 (26%), Positives = 351/876 (40%), Gaps = 189/876 (21%)
Query: 259 LCSERLGNSERVSAPDGPCPTGFERVNGSC----------EDVDECATGGRCQHGECANT 308
LC E + N + G C G + C + +DEC + G C +
Sbjct: 566 LCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDL 625
Query: 309 RGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSR 368
GY C C G +S +C + A PC G C + I + C CS
Sbjct: 626 VNGYQCNCQPG----TSGVNC-EINFDDCASNPCIH----GIC----MDGINRYSCVCSP 672
Query: 369 --VGKAWGRGCQLCPP----------FGSEGFREICPAGPGYHYSASDLRYNTRPLGQEP 416
G+ C G GFR ICP GP H+ + + N
Sbjct: 673 GFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGP--HHPSCYSQVNE------- 723
Query: 417 PRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTG--PEIPE 474
LS P + +G+ W G E+ +
Sbjct: 724 ---CLSNPCIHGNCTGGLSGY----------------------KCLCDAGWVGINCEVDK 758
Query: 475 SGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRC-IDVDECRRVP----- 528
+ S CQ G C + +GY C C GF+ G C +++DEC P
Sbjct: 759 NECLSNPCQNG------GTCDNLVNGYRCTCKKGFK----GYNCQVNIDECASNPCLNQG 808
Query: 529 --------------------------PPCAPGRCEN------SPG--SFRCVCGPGFRAG 554
PC+P CEN SP S+ C+C PG++ G
Sbjct: 809 TCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQ-G 867
Query: 555 PRAAECLDVDECHRVPPPC-DLGRCENTPGSFLCVCPAGYQAAPHGASC-QDVDECTQSP 612
R +D+DEC + PC + G C NT GS++C CP G+ G C +D+D+C +P
Sbjct: 868 QRCT--IDIDEC--ISKPCMNHGLCHNTQGSYMCECPPGFS----GMDCEEDIDDCLANP 919
Query: 613 GLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPA 672
G G+C + +F C+C GF G C+ D++EC EP G G C + S+ C C A
Sbjct: 920 CQNG-GSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNG-GTCSDYVNSYTCKCQA 977
Query: 673 GFRSRGPGAPCQ-DVDECARSPPPC-TYGRCENTEGSFQCVCPMGFQPNTAGSEC-EDVD 729
GF G C+ +++EC S C G C + SF C+CP+GF GS C +++
Sbjct: 978 GF----DGVHCENNINECTES--SCFNGGTCVDGINSFSCLCPVGF----TGSFCLHEIN 1027
Query: 730 ECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEG 789
EC +H CV+ G+++C +CP G + + T V+ CS PC G C +
Sbjct: 1028 ECSSHPCLNEGTCVDGLGTYRC-SCPLG-YTGKNCQTLVNLCSRS--PCKNKGTCVQKKA 1083
Query: 790 SFRCSCAPGYR-APSGRPGPCADVNECLEG----DFCFPHGECLNTDGSFACTCAPGYRP 844
+C C G+ A P D+ G C G C+N + C C GY
Sbjct: 1084 ESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGY-- 1141
Query: 845 GPRGASCLD-VDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASC-LDVDECRERG 902
G+ C + +DEC+ C++ G + C C PG++ +C +VDEC+ +
Sbjct: 1142 --TGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQG----VNCEYEVDECQNQ- 1194
Query: 903 PALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDD-VDECQEYGPEICGAQRCENTPGS 961
P G C + ++C C PG C++ +D+C GP +C + G
Sbjct: 1195 PCQNGG-TCIDLVNHFKC--SCPPGTRG---LLCEENIDDCAR-GPHCLNGGQCMDRIGG 1247
Query: 962 YRCTPACDPGYQPTPGGGCQ-DVDECRNRSFCGAHAV-CQNLPGSFQCLCDQGYEGARDG 1019
Y C C PG+ G C+ D++EC + ++ C L + C+C A G
Sbjct: 1248 YSC--RCLPGF---AGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVC----RSAFTG 1298
Query: 1020 RHC-VDVNECETLQGVCG--AALCENVEGSFLCVCP 1052
RHC V+ C + + G A+ N+ F+C CP
Sbjct: 1299 RHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCP 1334
Score = 244 bits (624), Expect = 4e-64
Identities = 271/988 (27%), Positives = 374/988 (37%), Gaps = 207/988 (20%)
Query: 475 SGPSSGMCQRN-----PQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCID-VDECRRVP 528
+G + +C+ N P C G+C YTC C+ G+ G C D +DEC P
Sbjct: 560 TGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGY----MGAICSDQIDECYSSP 615
Query: 529 ------------------------------------PPCAPGRCENSPGSFRCVCGPGFR 552
PC G C + + CVC PGF
Sbjct: 616 CLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMDGINRYSCVCSPGF- 674
Query: 553 AGPRAAECLDVDECHRVPPPCDLG-RCENTPGSFLCVCPAGYQAAPHGASC-QDVDECTQ 610
G R +D+DEC PC G C N F C+CP G PH SC V+EC
Sbjct: 675 TGQRCN--IDIDEC--ASNPCRKGATCINGVNGFRCICPEG----PHHPSCYSQVNECLS 726
Query: 611 SPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCAC 670
+P C G C ++C+C AG+ G CE D +EC P G G CDN + C C
Sbjct: 727 NP--CIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNG-GTCDNLVNGYRCTC 783
Query: 671 PAGFRSRGPGAPCQ-DVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDV- 728
GF+ G CQ ++DECA S P G C + + C C + + G C+ V
Sbjct: 784 KKGFK----GYNCQVNIDECA-SNPCLNQGTCFDDISGYTCHCVLPY----TGKNCQTVL 834
Query: 729 -----DECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCT-DVDECSSGAPPCGPHG 782
+ CEN C SP +F+ TC RCT D+DEC S PC HG
Sbjct: 835 APCSPNPCENAAVCK-----ESP-NFESYTCLCAPGWQGQRCTIDIDECIS--KPCMNHG 886
Query: 783 HCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGY 842
C NT+GS+ C C PG+ D+++CL C G C++ +F+C C PG+
Sbjct: 887 LCHNTQGSYMCECPPGFSGMDCE----EDIDDCLANP-CQNGGSCMDGVNTFSCLCLPGF 941
Query: 843 RPGPRGASC-LDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASC-LDVDECRE 900
G C D++EC E G C++ S+ C C +AG D C +++EC E
Sbjct: 942 ----TGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKC----QAGFDGVHCENNINECTE 993
Query: 901 RGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPG 960
G+ C + S+ C+ C G+ +++EC + C + G
Sbjct: 994 SSCFNGGT--CVDGINSFSCL--CPVGFTG--SFCLHEINECSSH--PCLNEGTCVDGLG 1045
Query: 961 SYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGR 1020
+YRC +C GY G CQ + +RS C C QCLC G+ GA
Sbjct: 1046 TYRC--SCPLGY---TGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDV 1100
Query: 1021 HCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQP 1080
V + + +GV LC++ S +C+ + T C P G++ Q
Sbjct: 1101 PNVSCDIAASRRGVLVEHLCQH---SGVCINAGN-------THYCQCPLGYTGSYCEEQL 1150
Query: 1081 QAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECC 1140
AS P + +G R EC C
Sbjct: 1151 DECASN-----------PCQHGATCSDFIGGYRCEC--------------VPGYQGVNCE 1185
Query: 1141 CTVGEGWGSGCRIQQCPGTETA-----EYQSLCPHG-RGYLAPSGDLSLRRDVDECQLFR 1194
V E C+ Q C T ++ CP G RG L ++D+C R
Sbjct: 1186 YEVDE-----CQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLC-------EENIDDCA--R 1231
Query: 1195 DQVC-KSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGG-RCVNTVGSY 1252
C G C++ GYSC C G + +R E D +EC + EG C+ Y
Sbjct: 1232 GPHCLNGGQCMDRIGGYSCRCLPG--FAGERCEG-DINECLSNPCSSEGSLDCIQLTNDY 1288
Query: 1253 HCTCEPPLVLDGSQRRC-----VSNESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTE 1307
C C + R C V + L+ + +C P A
Sbjct: 1289 LCVCRSAF----TGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQS 1344
Query: 1308 CC----CLYGE-----AWGMDCALCPAQDSDDFEALCNVLRPPAYSPPRPGGFGLPYE-- 1356
C C GE A G C CP+ D E+ C A SP + GG P
Sbjct: 1345 SCGQVKCRKGEQCVHTASGPRC-FCPS--PRDCESGC------ASSPCQHGGSCHPQRQP 1395
Query: 1357 --YGPDLGPPYQGLPYGPELY-PPPALP 1381
Y PP+ G ELY PP+ P
Sbjct: 1396 PYYSCQCAPPFSGSRC--ELYTAPPSTP 1421
Score = 241 bits (616), Expect = 3e-63
Identities = 266/969 (27%), Positives = 370/969 (38%), Gaps = 220/969 (22%)
Query: 469 GPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRC-IDVDECRRV 527
GP P C NP C G C SGY C CD+G+ G C +D +EC +
Sbjct: 711 GPHHPSCYSQVNECLSNP--CIHGNCTGGLSGYKCLCDAGW----VGINCEVDKNEC--L 762
Query: 528 PPPCAPG-RCENSPGSFRCVCGPGFRAGPRAAEC-LDVDEC------------------- 566
PC G C+N +RC C GF+ C +++DEC
Sbjct: 763 SNPCQNGGTCDNLVNGYRCTCKKGFKG----YNCQVNIDECASNPCLNQGTCFDDISGYT 818
Query: 567 -HRVPP-----------PCDLGRCENTP--------GSFLCVCPAGYQAAPHGASCQ-DV 605
H V P PC CEN S+ C+C G+Q G C D+
Sbjct: 819 CHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQ----GQRCTIDI 874
Query: 606 DECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGS 665
DEC P + G C N GS+ C CP GF G CEED+D+C P G G C + +
Sbjct: 875 DECISKPCM-NHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNG-GSCMDGVNT 932
Query: 666 FHCACPAGFRSRGPGAPCQ-DVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSE 724
F C C GF G CQ D++EC S P G C + S+ C C GF G
Sbjct: 933 FSCLCLPGF----TGDKCQTDMNECL-SEPCKNGGTCSDYVNSYTCKCQAGFD----GVH 983
Query: 725 CE-DVDECENHLACPGQECVNSPGSFQCRTCPSGHH----LHRGRCTDVDECSSGAPPCG 779
CE +++EC G CV+ SF C CP G LH +++ECSS PC
Sbjct: 984 CENNINECTESSCFNGGTCVDGINSFSC-LCPVGFTGSFCLH-----EINECSS--HPCL 1035
Query: 780 PHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCA 839
G C + G++RCSC GY + C + C G C+ C C
Sbjct: 1036 NEGTCVDGLGTYRCSCPLGYTGKN-----CQTLVNLCSRSPCKNKGTCVQKKAESQCLCP 1090
Query: 840 PGYRPGPRGASCLDVDECS-----------EEDLCQ-SGICTNTDGSFECICPPGHRAGP 887
G+ GA C DV S E LCQ SG+C N + C CP G+
Sbjct: 1091 SGW----AGAYC-DVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTG-- 1143
Query: 888 DLASCLD-VDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCD-DVDECQEY 945
+ C + +DEC P G+ C + G YRC +C PGY C+ +VDECQ
Sbjct: 1144 --SYCEEQLDECAS-NPCQHGA-TCSDFIGGYRC--ECVPGYQG---VNCEYEVDECQNQ 1194
Query: 946 GPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQD-VDECRNRSFCGAHAVCQNLPGS 1004
+ G C + ++C +C PG T G C++ +D+C C C + G
Sbjct: 1195 PCQNGGT--CIDLVNHFKC--SCPPG---TRGLLCEENIDDCARGPHCLNGGQCMDRIGG 1247
Query: 1005 FQCLCDQGYEGAR-DGRHCVDVNECETLQGVC---GAALCENVEGSFLCVCPNSPEEFDP 1060
+ C C G+ G R +G D+NEC L C G+ C + +LCVC ++
Sbjct: 1248 YSCRCLPGFAGERCEG----DINEC--LSNPCSSEGSLDCIQLTNDYLCVCRSA------ 1295
Query: 1061 MTGRCVPPRTSAGTFPGSQPQAP----ASPVLPARPPPPPLPRRPSTPRQGPVGSGRREC 1116
TGR TF PQ P + + + P + R P P SG R
Sbjct: 1296 FTGR------HCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCP------PGFSGAR-- 1341
Query: 1117 YFDTAAPDACDNILAR-------NVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCP 1169
+C + R + C C SGC C + Q P
Sbjct: 1342 -----CQSSCGQVKCRKGEQCVHTASGPRCFCPSPRDCESGCASSPCQHGGSCHPQRQPP 1396
Query: 1170 HGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSC---YCSNGYYYHTQRLE 1226
+ AP F C+ + P +C YC++ + +
Sbjct: 1397 YYSCQCAPP--------------FSGSRCELYTAPPSTPPATCLSQYCAD------KARD 1436
Query: 1227 CIDNDECADEEPACEGGRCVNTVGSYHCTCEPPL-VLDGSQRRC--VSNESQSLDDNLGV 1283
+ ++ C +GG C T+ + C PL D +C + N + L DN
Sbjct: 1437 GVCDEACNSHACQWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTVECLFDN--- 1493
Query: 1284 CWQEVGADLVCSHPR----------LDRQATYTECCCLYGEAW-GMDCALCPAQDSDDFE 1332
++ G C + + D+ EC W G+DCA ++ +
Sbjct: 1494 -FECQGNSKTCKYDKYCADHFKDNHCDQGCNSEEC------GWDGLDCAADQPENLAEGT 1546
Query: 1333 ALCNVLRPP 1341
+ VL PP
Sbjct: 1547 LVIVVLMPP 1555
Score = 162 bits (410), Expect = 2e-39
Identities = 152/515 (29%), Positives = 197/515 (38%), Gaps = 110/515 (21%)
Query: 595 AAP-HGASCQDVDECTQSPGLC-----GRGACKNLPGSFRCVCPAGFRGSACEEDVDECA 648
AAP H C+D E + G+C G G CK CP GF G C
Sbjct: 20 AAPAHALQCRDGYEPCVNEGMCVTYHNGTGYCK---------CPEGFLGEYC-------- 62
Query: 649 QEPPPCGPGRCDN--------TAGSFHCACPAGFRSRGPGAPCQ--DVDECARSPPPCTY 698
Q PC RC N G C C +GF G CQ C S P
Sbjct: 63 QHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGF----TGEDCQYSTSHPCFVSRPCLNG 118
Query: 699 GRCEN-TEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSG 757
G C + +++C C +GF G EC+ D C +H G C F C+ C +G
Sbjct: 119 GTCHMLSRDTYECTCQVGF----TGKECQWTDACLSHPCANGSTCTTVANQFSCK-CLTG 173
Query: 758 HHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAP--SGRPGPCADVNEC 815
+ TDV+EC C G C N GS++C C G+ PCA + C
Sbjct: 174 FTGQKCE-TDVNECDIPG-HCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAP-SPC 230
Query: 816 LEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASC-LDVDECSEEDLCQSGICTNTDGS 874
+ G C G D +F C C PG+ G++C ++D+C G+C + +
Sbjct: 231 VNGGTCRQTG-----DFTFECNCLPGF----EGSTCERNIDDCPNHRCQNGGVCVDGVNT 281
Query: 875 FECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCV------------- 921
+ C CPP G DVDEC + A C N G Y CV
Sbjct: 282 YNCRCPP-QWTGQFCTE--DVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSEN 338
Query: 922 ------RDCDPGYHA-------------GPEGTCDDVDECQEYGPEICGAQRCENTP--G 960
C PG G G +D+ P GA C+ P G
Sbjct: 339 IDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGA-LCDTNPLNG 397
Query: 961 SYRCTPACDPGYQPTPGGGC-QDVDEC--RNRSFCGAHAVCQNLPGSFQCLCDQGYEGAR 1017
Y CT C GY+ G C +DVDEC N + C C N G+F C C +GY G R
Sbjct: 398 QYICT--CPQGYK---GADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPR 452
Query: 1018 DGRHC-VDVNECETLQGVCGAALCENVEGSFLCVC 1051
C +D+NEC + A C + G F C+C
Sbjct: 453 ----CEMDINECHS-DPCQNDATCLDKIGGFTCLC 482
Score = 115 bits (288), Expect = 3e-25
Identities = 176/678 (25%), Positives = 255/678 (37%), Gaps = 132/678 (19%)
Query: 228 GGECASPLPGLRTQEVCC----RGAGLAWGVHDC--QLCSERLGNSERVSAPDGPCPTGF 281
GG C + G+ T C G +++C + C S+ V++ C GF
Sbjct: 923 GGSC---MDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGF 979
Query: 282 ERVNGSCED-VDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEA-- 338
+ V+ CE+ ++EC G C + ++C+CP GF + S C+ H I+E
Sbjct: 980 DGVH--CENNINECTESSCFNGGTCVDGINSFSCLCPVGF----TGSFCL--HEINECSS 1031
Query: 339 -----KGPCFRVLRDGGCSLPI---LRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFRE 390
+G C L CS P+ +N + CSR +G C +E +
Sbjct: 1032 HPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSR-SPCKNKG--TCVQKKAES-QC 1087
Query: 391 ICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPE-P 449
+CP+G Y + P VS + A+ R G L H +
Sbjct: 1088 LCPSGWAGAYC-------------DVPNVSCD----IAASRR---GVLVEHLCQHSGVCI 1127
Query: 450 RPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGF 509
+ PL ++ ++ E +S CQ C GY C C G+
Sbjct: 1128 NAGNTHYCQCPLGYTGSYCEEQLDEC--ASNPCQHG------ATCSDFIGGYRCECVPGY 1179
Query: 510 RLSPQGTRC-IDVDECRRVPPPCA-PGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECH 567
QG C +VDEC+ PC G C + F+C C PG R G E ++D+C
Sbjct: 1180 ----QGVNCEYEVDECQN--QPCQNGGTCIDLVNHFKCSCPPGTR-GLLCEE--NIDDCA 1230
Query: 568 RVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQ-DVDECTQSP-GLCGRGACKNLPG 625
R P + G+C + G + C C G+ G C+ D++EC +P G C L
Sbjct: 1231 RGPHCLNGGQCMDRIGGYSCRCLPGFA----GERCEGDINECLSNPCSSEGSLDCIQLTN 1286
Query: 626 SFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRC---DNTAGSFHCACPAGFRSRGPGAP 682
+ CVC + F G CE VD C Q P G G C N F C CP GF GA
Sbjct: 1287 DYLCVCRSAFTGRHCETFVDVCPQMPCLNG-GTCAVASNMPDGFICRCPPGF----SGAR 1341
Query: 683 CQDVDECARSPPPCTYG-RCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQE 741
CQ C + C G +C +T +C CP P S C C++ +C Q
Sbjct: 1342 CQ--SSCGQ--VKCRKGEQCVHTASGPRCFCP---SPRDCESGCAS-SPCQHGGSCHPQ- 1392
Query: 742 CVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRA 801
P + C+ P RC APP P +C Y A
Sbjct: 1393 --RQPPYYSCQCAPP---FSGSRCE-----LYTAPPSTP-----------PATCLSQYCA 1431
Query: 802 PSGRPGPCADVNECLEGDFC-FPHGEC-LNTDGSFACTCAPGYRPGPRGASCLDVDECSE 859
R G C +E C + G+C L + +A +P C D
Sbjct: 1432 DKARDGVC---DEACNSHACQWDGGDCSLTMENPWANCSSP--------LPCWDYINNQC 1480
Query: 860 EDLCQSGICTNTDGSFEC 877
++LC + C +FEC
Sbjct: 1481 DELCNTVEC--LFDNFEC 1496
Score = 83.6 bits (205), Expect = 1e-15
Identities = 124/481 (25%), Positives = 164/481 (34%), Gaps = 120/481 (24%)
Query: 835 ACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLD 894
A C GY P C E +C T +G+ C CP G
Sbjct: 25 ALQCRDGYEP------------CVNEGMC----VTYHNGTGYCKCPEGFLG--------- 59
Query: 895 VDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQR 954
+ C+ R P C RC+N CV G + ++CQ C R
Sbjct: 60 -EYCQHRDP--CEKNRCQNGG---TCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSR 113
Query: 955 -CEN-------TPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQ 1006
C N + +Y CT C G+ G CQ D C + C + C + F
Sbjct: 114 PCLNGGTCHMLSRDTYECT--CQVGFT---GKECQWTDACLSHP-CANGSTCTTVANQFS 167
Query: 1007 CLCDQGYEGARDGRHC-VDVNECETLQGVCG-AALCENVEGSFLCVCPN--SPEEFDPMT 1062
C C G+ G + C DVNEC+ + G C C N+ GS+ C CP + + D +
Sbjct: 168 CKCLTGFTGQK----CETDVNECD-IPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLY 222
Query: 1063 GRCVP-PRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTP----------------- 1104
C P P + GT + LP P
Sbjct: 223 VPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTY 282
Query: 1105 --RQGPVGSGR------RECYFDTAAPDACDN--ILARNVTWQECCCTVGEGW-GSGC-- 1151
R P +G+ EC P+AC N A C C GW G C
Sbjct: 283 NCRCPPQWTGQFCTEDVDECLLQ---PNACQNGGTCANRNGGYGCVCV--NGWSGDDCSE 337
Query: 1152 RIQQC------PGT----ETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSG 1201
I C PG+ A + +CP G+ L D D C C G
Sbjct: 338 NIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLD-------DAC---ISNPCHKG 387
Query: 1202 VCVNTAP---GYSCYCSNGYYYHTQRLECI-DNDEC--ADEEPACEGGRCVNTVGSYHCT 1255
+T P Y C C GY + +C D DEC A+ P G+CVNT G++HC
Sbjct: 388 ALCDTNPLNGQYICTCPQGY----KGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCE 443
Query: 1256 C 1256
C
Sbjct: 444 C 444
Score = 62.8 bits (151), Expect = 3e-09
Identities = 113/483 (23%), Positives = 170/483 (35%), Gaps = 89/483 (18%)
Query: 90 CHNGGVCV---KPDRCLCPPDFAGKFC--QLHSSGARP---PAPAVPGLTRSVYTMPLAN 141
C NGG CV CLCP F G FC +++ + P V GL + PL
Sbjct: 996 CFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGY 1055
Query: 142 HRDDEHGVASMVSVHVEHPQEASVVVHQVER---VSGPWEEADAEA------VARAEAAA 192
+ + ++ S + + V + E W A + +A +
Sbjct: 1056 TGKNCQTLVNLCS-RSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGV 1114
Query: 193 RAEAAAPYTVLAQSAPREDGYSDASGF--GYCFREL---------RGGECASPLPGLRTQ 241
E ++ + +A G+ YC +L G C+ + G R +
Sbjct: 1115 LVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCE 1174
Query: 242 EV-CCRGAGLAWGVHDCQLCSERLGNS--ERVSAPDGPCPTGFERVNGSCED-VDECATG 297
V +G + V +CQ + G + + V+ CP G + CE+ +D+CA G
Sbjct: 1175 CVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGL--LCEENIDDCARG 1232
Query: 298 GRCQH-GECANTRGGYTCVCPDGFL---LDSSRSSCISQHVISEAKGPCFRVLRDGGCSL 353
C + G+C + GGY+C C GF + + C+S SE C ++ D
Sbjct: 1233 PHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTND----- 1287
Query: 354 PILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLG 413
+C C GR C E F ++CP P + + N P G
Sbjct: 1288 --------YLCVCR--SAFTGRHC--------ETFVDVCPQMPCLNGGTCAVASN-MPDG 1328
Query: 414 QEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIP 473
+ P A + S G + + E GP PS P
Sbjct: 1329 ----FICRCPPGFSGARCQSSCGQVKCR----KGEQCVHTASGPRCFCPS------PRDC 1374
Query: 474 ESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAP 533
ESG +S CQ C P R +P Y+C C F G+RC E PP P
Sbjct: 1375 ESGCASSPCQHGGS-CHPQR---QPPYYSCQCAPPF----SGSRC----ELYTAPPSTPP 1422
Query: 534 GRC 536
C
Sbjct: 1423 ATC 1425
Score = 52.0 bits (123), Expect = 4e-06
Identities = 33/104 (31%), Positives = 46/104 (44%), Gaps = 14/104 (13%)
Query: 1449 PEGGSYAGSLAEPYEELEA----EECGILDG--CTN-GRCVRVPEGFTCRCFDGYRLDMT 1501
P G Y + + Y+ + +EC + + C + G+CV F C C GY
Sbjct: 394 PLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRC 453
Query: 1502 RMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTH 1545
M DINEC + P +A CL+ G F C+C PGF H
Sbjct: 454 EM---DINECH----SDPCQNDATCLDKIGGFTCLCMPGFKGVH 490
Score = 47.0 bits (110), Expect = 1e-04
Identities = 29/85 (34%), Positives = 44/85 (51%), Gaps = 11/85 (12%)
Query: 1459 AEPYEELEAEECGILDGCTN-GRCVRVPEGFTCRCFDGYRLDMTRMAC-VDINECDEAEA 1516
A P E++ EC D C N C+ GFTC C G++ + C ++INEC
Sbjct: 449 AGPRCEMDINECHS-DPCQNDATCLDKIGGFTCLCMPGFK----GVHCELEINECQ---- 499
Query: 1517 ASPLCVNARCLNTDGSFRCICRPGF 1541
++P N +C++ F+C+C PGF
Sbjct: 500 SNPCVNNGQCVDKVNRFQCLCPPGF 524
Score = 46.6 bits (109), Expect = 2e-04
Identities = 24/46 (52%), Positives = 25/46 (54%), Gaps = 4/46 (8%)
Query: 277 CPTGFERVNGSCE-DVDECATGGRCQHG-ECANTRGGYTCVCPDGF 320
C TGF CE DV+EC G CQHG C N G Y C CP GF
Sbjct: 170 CLTGF--TGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGF 213
Score = 44.3 bits (103), Expect = 0.001
Identities = 27/82 (32%), Positives = 34/82 (41%), Gaps = 9/82 (10%)
Query: 1476 CTNGR-CVRVPEGFTCRCFDGYRLDMTRMAC-VDINECDEAEAASPLCVNARCLNTDGSF 1533
C NG C V F+C+C G+ T C D+NECD CLN GS+
Sbjct: 153 CANGSTCTTVANQFSCKCLTGF----TGQKCETDVNECDIPGHCQH---GGTCLNLPGSY 205
Query: 1534 RCICRPGFAPTHQPHHCAPARP 1555
+C C GF + P P
Sbjct: 206 QCQCPQGFTGQYCDSLYVPCAP 227
Score = 43.5 bits (101), Expect = 0.002
Identities = 28/87 (32%), Positives = 42/87 (48%), Gaps = 16/87 (18%)
Query: 1464 ELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMAC-VDINECDEAEAASPLCV 1522
E+ ++C + C +G C+ ++C C G+ T C +DI+EC A++P
Sbjct: 643 EINFDDCAS-NPCIHGICMDGINRYSCVCSPGF----TGQRCNIDIDEC----ASNPCRK 693
Query: 1523 NARCLNTDGSFRCICRPGFAPTHQPHH 1549
A C+N FRCIC G PHH
Sbjct: 694 GATCINGVNGFRCICPEG------PHH 714
Score = 43.1 bits (100), Expect = 0.002
Identities = 39/136 (28%), Positives = 57/136 (41%), Gaps = 24/136 (17%)
Query: 220 GYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDG---P 276
G C ++ +C P PG T VC + DC + L ++ + P+G
Sbjct: 507 GQCVDKVNRFQCLCP-PGF-TGPVC------QIDIDDCS-STPCLNGAKCIDHPNGYECQ 557
Query: 277 CPTGFERVNGSCED-VDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVI 335
C TGF V CE+ +D C C HG+C + YTC+C G++ + S +
Sbjct: 558 CATGFTGV--LCEENIDNCDPDP-CHHGQCQDGIDSYTCICNPGYM-----GAICSDQID 609
Query: 336 SEAKGPCFRVLRDGGC 351
PC L DG C
Sbjct: 610 ECYSSPC---LNDGRC 622
Score = 43.1 bits (100), Expect = 0.002
Identities = 21/82 (25%), Positives = 39/82 (47%), Gaps = 10/82 (12%)
Query: 1461 PYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVD-INECDEAEAASP 1519
P +++ ++C +C+ P G+ C+C G+ T + C + I+ CD
Sbjct: 527 PVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGF----TGVLCEENIDNCDPDP---- 578
Query: 1520 LCVNARCLNTDGSFRCICRPGF 1541
C + +C + S+ CIC PG+
Sbjct: 579 -CHHGQCQDGIDSYTCICNPGY 599
Score = 42.4 bits (98), Expect = 0.004
Identities = 30/104 (28%), Positives = 43/104 (41%), Gaps = 11/104 (10%)
Query: 220 GYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQ---LCSERLGNSERVSAPDGP 276
G CF ++ G C LP C+ + C+ +C E S +
Sbjct: 808 GTCFDDISGYTCHCVLPYTGKN---CQTVLAPCSPNPCENAAVCKE----SPNFESYTCL 860
Query: 277 CPTGFERVNGSCEDVDECATGGRCQHGECANTRGGYTCVCPDGF 320
C G++ + D+DEC + HG C NT+G Y C CP GF
Sbjct: 861 CAPGWQGQRCTI-DIDECISKPCMNHGLCHNTQGSYMCECPPGF 903
Score = 41.2 bits (95), Expect = 0.008
Identities = 24/69 (34%), Positives = 34/69 (49%), Gaps = 8/69 (11%)
Query: 255 HDCQLCSERLGNSERVSAPDGPCPTGFERVNGSCEDVDECATGGR--CQH-GECANTRGG 311
H LC N + + CP G++ + + EDVDECA C+H G+C NT G
Sbjct: 385 HKGALCDTNPLNGQYICT----CPQGYKGADCT-EDVDECAMANSNPCEHAGKCVNTDGA 439
Query: 312 YTCVCPDGF 320
+ C C G+
Sbjct: 440 FHCECLKGY 448
Score = 41.2 bits (95), Expect = 0.008
Identities = 26/81 (32%), Positives = 38/81 (46%), Gaps = 10/81 (12%)
Query: 1464 ELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVD-INECDEAEAASPLCV 1522
E E +EC G C+ + F C C G R + C + I++C A P C+
Sbjct: 1185 EYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTR----GLLCEENIDDC----ARGPHCL 1236
Query: 1523 NA-RCLNTDGSFRCICRPGFA 1542
N +C++ G + C C PGFA
Sbjct: 1237 NGGQCMDRIGGYSCRCLPGFA 1257
Score = 40.8 bits (94), Expect = 0.010
Identities = 20/57 (35%), Positives = 30/57 (52%), Gaps = 7/57 (12%)
Query: 1486 EGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFA 1542
E +TC C G++ + +DI+EC + P + C NT GS+ C C PGF+
Sbjct: 855 ESYTCLCAPGWQ---GQRCTIDIDEC----ISKPCMNHGLCHNTQGSYMCECPPGFS 904
Score = 40.4 bits (93), Expect = 0.013
Identities = 22/76 (28%), Positives = 35/76 (46%), Gaps = 8/76 (10%)
Query: 1466 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNAR 1525
+ +EC +GRC+ + G+ C C G T +IN D AS C++
Sbjct: 607 QIDECYSSPCLNDGRCIDLVNGYQCNCQPG-----TSGVNCEINFDD---CASNPCIHGI 658
Query: 1526 CLNTDGSFRCICRPGF 1541
C++ + C+C PGF
Sbjct: 659 CMDGINRYSCVCSPGF 674
Score = 38.9 bits (89), Expect = 0.039
Identities = 26/83 (31%), Positives = 34/83 (40%), Gaps = 15/83 (18%)
Query: 1464 ELEAEECGILDGCTNG-RCVRVPEGFTCRC---FDGYRLDMTRMACVDINECDEAEAASP 1519
E + EC I C +G C+ +P + C+C F G D + C A SP
Sbjct: 180 ETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPC----------APSP 229
Query: 1520 LCVNARCLNT-DGSFRCICRPGF 1541
C T D +F C C PGF
Sbjct: 230 CVNGGTCRQTGDFTFECNCLPGF 252
Score = 38.9 bits (89), Expect = 0.039
Identities = 23/83 (27%), Positives = 37/83 (44%), Gaps = 6/83 (7%)
Query: 1464 ELEAEECGILDGCTNG-RCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCV 1522
E ++C C NG +C+ G++CRC G+ + DINEC +S +
Sbjct: 1223 EENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEG---DINECLSNPCSSEGSL 1279
Query: 1523 NARCLNTDGSFRCICRPGFAPTH 1545
+ C+ + C+CR F H
Sbjct: 1280 D--CIQLTNDYLCVCRSAFTGRH 1300
Score = 38.1 bits (87), Expect = 0.067
Identities = 28/96 (29%), Positives = 44/96 (45%), Gaps = 20/96 (20%)
Query: 1464 ELEAEECGILDGCTNG-RCVRVPEGFTCRC---FDGYRLDMTRMACVDINECDEAEAASP 1519
+ + EC + + C NG C +TC+C FDG + +INEC E+
Sbjct: 947 QTDMNEC-LSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCEN------NINECTESS---- 995
Query: 1520 LCVNA-RCLNTDGSFRCICRPGFAPT---HQPHHCA 1551
C N C++ SF C+C GF + H+ + C+
Sbjct: 996 -CFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECS 1030
Score = 37.4 bits (85), Expect = 0.11
Identities = 29/88 (32%), Positives = 36/88 (40%), Gaps = 17/88 (19%)
Query: 45 CVHGPTGSRCTPTCAPRNATSVDSGAPGGAAPGG------PGFRAFLCPLI--------C 90
C+ G G RC ++ + A GG PGF+ C L C
Sbjct: 444 CLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPC 503
Query: 91 HNGGVCV-KPDR--CLCPPDFAGKFCQL 115
N G CV K +R CLCPP F G CQ+
Sbjct: 504 VNNGQCVDKVNRFQCLCPPGFTGPVCQI 531
Score = 37.0 bits (84), Expect = 0.15
Identities = 25/78 (32%), Positives = 34/78 (43%), Gaps = 12/78 (15%)
Query: 1466 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDIN-ECDEAEAASPLCVNA 1524
+ EC + + C +G C G+ C C G+ V IN E D+ E S C N
Sbjct: 720 QVNEC-LSNPCIHGNCTGGLSGYKCLCDAGW---------VGINCEVDKNECLSNPCQNG 769
Query: 1525 -RCLNTDGSFRCICRPGF 1541
C N +RC C+ GF
Sbjct: 770 GTCDNLVNGYRCTCKKGF 787
Score = 36.2 bits (82), Expect = 0.25
Identities = 28/88 (31%), Positives = 32/88 (36%), Gaps = 18/88 (20%)
Query: 44 RCVHGPTGSRCTPT---CAP----RNATSVDSGAPGGAAPGGPGFRAFLCPLI------- 89
+C G TG C CAP T +G PGF C
Sbjct: 208 QCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNH 267
Query: 90 -CHNGGVCV---KPDRCLCPPDFAGKFC 113
C NGGVCV C CPP + G+FC
Sbjct: 268 RCQNGGVCVDGVNTYNCRCPPQWTGQFC 295
Score = 36.2 bits (82), Expect = 0.25
Identities = 29/102 (28%), Positives = 45/102 (44%), Gaps = 15/102 (14%)
Query: 1446 EEPPEGGSYAGSLAEPYE----ELEAEECGILDGCTN-GRCVRVPEGFTCRCFDGYRLDM 1500
+E P SY A ++ ++ +EC I C N G C + C C G+
Sbjct: 849 KESPNFESYTCLCAPGWQGQRCTIDIDEC-ISKPCMNHGLCHNTQGSYMCECPPGF---- 903
Query: 1501 TRMACV-DINECDEAEAASPLCVNARCLNTDGSFRCICRPGF 1541
+ M C DI++C A+P C++ +F C+C PGF
Sbjct: 904 SGMDCEEDIDDC----LANPCQNGGSCMDGVNTFSCLCLPGF 941
Score = 35.8 bits (81), Expect = 0.33
Identities = 32/108 (29%), Positives = 46/108 (42%), Gaps = 29/108 (26%)
Query: 26 GRLGERLRVRFTPVVC--GLRCVHGPTGSRCTPTCAPRNATSVDSGAPGGAAPGGPGFRA 83
G G R + V C G +CVH +G RC +PR+ S + +P
Sbjct: 1336 GFSGARCQSSCGQVKCRKGEQCVHTASGPRCF-CPSPRDCESGCASSP------------ 1382
Query: 84 FLCPLICHNGGVCVKPDR------CLCPPDFAGKFCQLHSS-GARPPA 124
C +GG C P R C C P F+G C+L+++ + PPA
Sbjct: 1383 ------CQHGGSC-HPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPA 1423
Score = 34.7 bits (78), Expect = 0.74
Identities = 52/216 (24%), Positives = 71/216 (32%), Gaps = 48/216 (22%)
Query: 85 LCPLI-CHNGGVCV----KPDR--CLCPPDFAGKFCQLHSSGARPPAPAVPGLTRSVYTM 137
+CP + C NGG C PD C CPP F+G CQ + T S
Sbjct: 1307 VCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRC 1366
Query: 138 PLANHRDDEHGVASMVSVHVE--HPQEASVVVHQVERVSGPWEEADAEAVARAEAAARAE 195
+ RD E G AS H HPQ + A + +R E
Sbjct: 1367 FCPSPRDCESGCASSPCQHGGSCHPQRQPPYY--------SCQCAPPFSGSRCELYTAPP 1418
Query: 196 AAAPYTVLAQSAPREDGYSDASGFGYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGVH 255
+ P T L+Q YC + R G C + C W
Sbjct: 1419 STPPATCLSQ---------------YCADKARDGVC----------DEACNSHACQWDGG 1453
Query: 256 DCQLCSERLGNSERVSAPDGPCPTGFERVNGSCEDV 291
DC L E N + PC ++ +N C+++
Sbjct: 1454 DCSLTME---NPWANCSSPLPC---WDYINNQCDEL 1483
Score = 33.1 bits (74), Expect = 2.1
Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 11/80 (13%)
Query: 1464 ELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACV-DINECDEAEAASPLCV 1522
E EC G CV F+C C G+ T C+ +INEC +S C+
Sbjct: 985 ENNINECTESSCFNGGTCVDGINSFSCLCPVGF----TGSFCLHEINEC-----SSHPCL 1035
Query: 1523 N-ARCLNTDGSFRCICRPGF 1541
N C++ G++RC C G+
Sbjct: 1036 NEGTCVDGLGTYRCSCPLGY 1055
Score = 32.3 bits (72), Expect = 3.7
Identities = 25/88 (28%), Positives = 31/88 (35%), Gaps = 17/88 (19%)
Query: 44 RCVHGPTGSRCTPTCAPRNATSVDSGAPGGAAPGG------PGFRAFLCPLI-------- 89
+C G TGS C + GA GG PG++ C
Sbjct: 1136 QCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQP 1195
Query: 90 CHNGGVC---VKPDRCLCPPDFAGKFCQ 114
C NGG C V +C CPP G C+
Sbjct: 1196 CQNGGTCIDLVNHFKCSCPPGTRGLLCE 1223
Score = 32.0 bits (71), Expect = 4.8
Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 9/65 (13%)
Query: 1478 NGRCVRVPEGFTCRCFDGYRLDMTRMACVD-INECDEAEAASPLCVNARCLNTDGSFRCI 1536
+G C+ C+C GY T C + ++EC A++P A C + G +RC
Sbjct: 1123 SGVCINAGNTHYCQCPLGY----TGSYCEEQLDEC----ASNPCQHGATCSDFIGGYRCE 1174
Query: 1537 CRPGF 1541
C PG+
Sbjct: 1175 CVPGY 1179
Score = 31.6 bits (70), Expect = 6.3
Identities = 22/78 (28%), Positives = 34/78 (43%), Gaps = 15/78 (19%)
Query: 1464 ELEAEECGILDGCTNG-RCVRVPEGFTCRC---FDGYRLDMTRMACVDINECDEAEAASP 1519
E++ EC + + C NG C + G+ C C F GY V+I+EC A++P
Sbjct: 755 EVDKNEC-LSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQ------VNIDEC----ASNP 803
Query: 1520 LCVNARCLNTDGSFRCIC 1537
C + + C C
Sbjct: 804 CLNQGTCFDDISGYTCHC 821
Score = 31.6 bits (70), Expect = 6.3
Identities = 23/89 (25%), Positives = 33/89 (37%), Gaps = 19/89 (21%)
Query: 45 CVHGPTGSRCTPTCAPRNATSVDSGAPGGAAPG--------GPGFRAFLCPLI------- 89
CV TG C AP + ++ A +P PG++ C +
Sbjct: 821 CVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISK 880
Query: 90 -CHNGGVCVKPD---RCLCPPDFAGKFCQ 114
C N G+C C CPP F+G C+
Sbjct: 881 PCMNHGLCHNTQGSYMCECPPGFSGMDCE 909
Score = 31.6 bits (70), Expect = 6.3
Identities = 18/65 (27%), Positives = 30/65 (46%), Gaps = 10/65 (15%)
Query: 1473 LDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGS 1532
L+G T +P+GF CRC G+ + +C + +C + E +C++T
Sbjct: 1314 LNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQV-KCRKGE---------QCVHTASG 1363
Query: 1533 FRCIC 1537
RC C
Sbjct: 1364 PRCFC 1368
Score = 31.2 bits (69), Expect = 8.2
Identities = 26/102 (25%), Positives = 34/102 (33%), Gaps = 27/102 (26%)
Query: 42 GLRCVHGPTGSRCT-------PTCAPRNATSVDSGAPGGAAPGGPGFRAFLCPL------ 88
G C++G G RC P+C + + + G GG LC
Sbjct: 694 GATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGIN 753
Query: 89 -----------ICHNGGVC---VKPDRCLCPPDFAGKFCQLH 116
C NGG C V RC C F G CQ++
Sbjct: 754 CEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVN 795
>gi|51873055 fibulin 2 isoform b precursor [Homo sapiens]
Length = 1184
Score = 265 bits (678), Expect = 2e-70
Identities = 222/700 (31%), Positives = 293/700 (41%), Gaps = 98/700 (14%)
Query: 424 PRTLPATSRPSAGFLPTHRLEPR-PEPRP--------DPRPGPELPLPSIPAWTGP---- 470
P + +TS P A ++P R PR P+ P DP +P S T
Sbjct: 385 PHNILSTSLPDAAWIPPTREVPRKPQVLPHSHVEEDTDPNSVHSIPRSSPEGSTKDLIET 444
Query: 471 ----------------EIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQ 514
EIPESG +C+ + C C+S +C +G + +
Sbjct: 445 CCAAGQQWAIDNDECLEIPESGTEDNVCRTAQRHC----CVSYLQEKSCM--AGVLGAKE 498
Query: 515 GTRC--IDVDEC-----RRVPPPCAPG--------RCENSPGSFRCVCGPGFRAGPRAAE 559
G C D D C ++ C G CE++P + C + E
Sbjct: 499 GETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQSCESNP-NLGYPCNHVMLSCCEGEE 557
Query: 560 CLDVDECHRVPPPCDLGR--CENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGR 617
L V E R P P R E + P+ D DEC PG +
Sbjct: 558 PLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQDECLLLPGELCQ 617
Query: 618 GACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSR 677
C N GS+ C C F G + ++D C E P P A + A S
Sbjct: 618 HLCINTVGSYHCAC---FPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVA---SN 671
Query: 678 GPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDEC--ENHL 735
P + C + PC C GS C C G+ G CED++EC + H
Sbjct: 672 TIPLPLPQPNTC-KDNGPCKQV-CSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHT 729
Query: 736 ACPGQECVNSPGSFQCR---TCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFR 792
G+ CVN+ GSF C TC G+ L G C DVDEC+ G C P C NT+GSF
Sbjct: 730 CSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFY 789
Query: 793 CS----CAPGY-RAPSGRPGPCADVNECLE-GDFCFPHGECLNTDGSFACT-----CAPG 841
C C G+ + P G C D+NEC + C P C+NT GS+ C CA G
Sbjct: 790 CQARQRCMDGFLQDPEGN---CVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARG 846
Query: 842 YRPGPRGASCLDVDECSEE-DLCQSG-ICTNTDGSFECICPPGHRAGPDLASCLDVDECR 899
Y G C+DV+EC C G +C N GS+ C C G + C+DV+EC
Sbjct: 847 YHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECW 906
Query: 900 ERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGT-CDDVDECQEYGPEICGAQRCENT 958
LC CEN+ GSYRC C G+ +G C+DV+EC+ + C +Q C N
Sbjct: 907 ASPGRLC-QHTCENTLGSYRC--SCASGFLLAADGKRCEDVNECEA---QRC-SQECANI 959
Query: 959 PGSYRCTPACDPGYQPTPGGG-CQDVDECRNRSFCGAHAVCQNLPGSFQCLC-DQGYEGA 1016
GSY+C C GYQ G C D+DEC + C N+PGS+QC C +QGY
Sbjct: 960 YGSYQCY--CRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMT 1017
Query: 1017 RDGRHCVDVNECETLQGVCG-AALCENVEGSFLCV---CP 1052
+GR C DV+EC C A C N++GSF C+ CP
Sbjct: 1018 ANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRFECP 1057
Score = 254 bits (649), Expect = 5e-67
Identities = 208/627 (33%), Positives = 268/627 (42%), Gaps = 100/627 (15%)
Query: 358 NITKQICCCSRVG---KAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQ 414
++ KQ C C +G +A G+ C+ P G P H S G+
Sbjct: 513 SLYKQCCDCCGLGLRVRAEGQSCESNPNLGY----------PCNHVMLSCCE------GE 556
Query: 415 EPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLP---SIPAWTGPE 471
EP V P RP PEP PR E + ++ T E
Sbjct: 557 EPLIV--------PEVRRP-------------PEPAAAPRRVSEAEMAGREALSLGTEAE 595
Query: 472 IPESGPSSGM--CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPP 529
+P S P C P CI+ Y CAC GF L G C +
Sbjct: 596 LPNSLPGDDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEA 655
Query: 530 PCAPG-RCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCV 588
P P + E S + + P P+ C D C +V C GS +C
Sbjct: 656 PQEPALKSEFSQVASNTIPLP----LPQPNTCKDNGPCKQV--------CSTVGGSAICS 703
Query: 589 CPAGYQAAPHGASCQDVDECTQSPGLCGRGA-CKNLPGSFRC----VCPAGF--RGSACE 641
C GY G SC+D++EC C RG C N GSF C C G+ + C
Sbjct: 704 CFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGEC- 762
Query: 642 EDVDECAQEPPPCGPG-RCDNTAGSFHC----ACPAGFRSRGPGAPCQDVDECARSPPPC 696
EDVDECA C PG C NT GSF+C C GF + P C D++EC PC
Sbjct: 763 EDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGF-LQDPEGNCVDINECTSLSEPC 821
Query: 697 TYG-RCENTEGSFQC-----VCPMGFQPNTAGSECEDVDECEN--HLACPGQECVNSPGS 748
G C NT GS+ C +C G+ + G++C DV+ECE H GQ C N PGS
Sbjct: 822 RPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGS 881
Query: 749 FQCRTCPSGHH---LHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGY-RAPSG 804
++C C +G RG C DV+EC + H C NT GS+RCSCA G+ A G
Sbjct: 882 YRC-DCKAGFQRDAFGRG-CIDVNECWASPGRLCQH-TCENTLGSYRCSCASGFLLAADG 938
Query: 805 RPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSE-EDLC 863
+ C DVNEC E C EC N GS+ C C GY+ G +C D+DEC++ +
Sbjct: 939 K--RCEDVNEC-EAQRC--SQECANIYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGIL 993
Query: 864 QSGICTNTDGSFECICP-PGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVR 922
+ C N GS++C CP G+ + SC DVDEC ++ C N GS+RC+R
Sbjct: 994 CTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLR 1053
Query: 923 -DCDPGY-----HAGPEGTCDDVDECQ 943
+C P Y TC D ECQ
Sbjct: 1054 FECPPNYVQVSKTKCERTTCHDFLECQ 1080
Score = 164 bits (416), Expect = 5e-40
Identities = 221/874 (25%), Positives = 295/874 (33%), Gaps = 173/874 (19%)
Query: 430 TSRPSAGFLPTHRLEPRPEPRPDPRPGPE----LPLPSIPAWTGPEIPESGPSSGMCQRN 485
T+ P+ LP R + PE L + TGPE PS G
Sbjct: 309 TTAPAGPSLPIQEERAEAGARAEAGARPEENLILDAQATSRSTGPEGVTHAPSLGKAALV 368
Query: 486 PQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPC-APGRCENSPGSFR 544
P PG + + SP + + +PP P + + P S
Sbjct: 369 PTQAVPG-----------SPRDPVKPSPHNILSTSLPDAAWIPPTREVPRKPQVLPHS-- 415
Query: 545 CVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQD 604
E D + H +P G +T C AG Q A C +
Sbjct: 416 -----------HVEEDTDPNSVHSIPRSSPEG---STKDLIETCCAAGQQWAIDNDECLE 461
Query: 605 VDECTQSPGLCGRGACKNLPGSF--RCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNT 662
+ E +C R A ++ S+ C AG G A+E CG D+
Sbjct: 462 IPESGTEDNVC-RTAQRHCCVSYLQEKSCMAGVLG----------AKEGETCGAEDNDSC 510
Query: 663 AGSFH---C-ACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQP 718
S + C C G R R G C+ PC + EG + P +P
Sbjct: 511 GISLYKQCCDCCGLGLRVRAEGQSCESNPNLGY---PCNHVMLSCCEGEEPLIVPEVRRP 567
Query: 719 NTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPC 778
+ V E E G+E ++ + G D DEC
Sbjct: 568 PEPAAAPRRVSEAE----MAGREALSLGTEAELPNSLPGD--------DQDECLLLPGEL 615
Query: 779 GPHGHCTNTEGSFRCSCAPGYRA--------PSGRPG-PCADVNECLEGDF--------- 820
H C NT GS+ C+C PG+ P G P P A L+ +F
Sbjct: 616 CQH-LCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIP 674
Query: 821 --------CFPHGECLNT----DGSFACTCAPGYRPGPRGASCLDVDEC-SEEDLCQSGI 867
C +G C GS C+C PGY G SC D++EC ++ C G
Sbjct: 675 LPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGE 734
Query: 868 -CTNTDGSFECI----CPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCV- 921
C NT GSF C C PG+ C DVDEC C+N+ GS+ C
Sbjct: 735 HCVNTLGSFHCYKALTCEPGYALKD--GECEDVDECAMGTHTCQPGFLCQNTKGSFYCQA 792
Query: 922 -RDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTP---ACDPGYQPTPG 977
+ C G+ PEG C D++EC C NT GSY C C GY +
Sbjct: 793 RQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDD 852
Query: 978 GG-CQDVDECRNRSF-CGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNEC------- 1028
G C DV+EC CG VC NLPGS++C C G++ GR C+DVNEC
Sbjct: 853 GTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRL 912
Query: 1029 --ETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASP 1086
T + G+ C G L E+ + C R S Q A+
Sbjct: 913 CQHTCENTLGSYRCSCASGFLLAADGKRCEDVN----ECEAQRCS---------QECANI 959
Query: 1087 VLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEG 1146
G +CY A D ++ C G G
Sbjct: 960 Y------------------------GSYQCYCRQGYQLAEDGHTCTDIDE----CAQGAG 991
Query: 1147 WGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNT 1206
R PG+ YQ CP +GY + S + DVDEC L ++ C N
Sbjct: 992 ILCTFRCLNVPGS----YQCACPE-QGYTMTANGRSCK-DVDECALGTHNCSEAETCHNI 1045
Query: 1207 APGYSCY---CSNGYYY----HTQRLECIDNDEC 1233
+ C C Y +R C D EC
Sbjct: 1046 QGSFRCLRFECPPNYVQVSKTKCERTTCHDFLEC 1079
Score = 134 bits (336), Expect = 9e-31
Identities = 178/650 (27%), Positives = 223/650 (34%), Gaps = 146/650 (22%)
Query: 685 DVDECARSPPPCTYGRCENTEGSFQCV-------CPMGFQPNTAGSEC--EDVDECENHL 735
D DEC P T T CV C G G C ED D C L
Sbjct: 455 DNDECLEIPESGTEDNVCRTAQRHCCVSYLQEKSCMAGVLGAKEGETCGAEDNDSCGISL 514
Query: 736 ACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAP---PCGPHGHCTNTEGSFR 792
++C C C G + + C S PC H + EG
Sbjct: 515 Y---KQC--------CDCCGLGLRVR----AEGQSCESNPNLGYPCN-HVMLSCCEGE-E 557
Query: 793 CSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCL 852
P R P P P A E + L T+ P PG
Sbjct: 558 PLIVPEVRRP---PEPAAAPRRVSEAEMAGREALSLGTEAEL-----PNSLPGD------ 603
Query: 853 DVDECS--EEDLCQSGICTNTDGSFECICPPGHRAGPDLASCL----------------- 893
D DEC +LCQ +C NT GS+ C C PG D +C
Sbjct: 604 DQDECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALK 662
Query: 894 ----------------DVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEG-TC 936
+ C++ GP Q C GS C C PGY +G +C
Sbjct: 663 SEFSQVASNTIPLPLPQPNTCKDNGPC---KQVCSTVGGSAIC--SCFPGYAIMADGVSC 717
Query: 937 DDVDECQEYGPEICGAQRCENTPGSYRCTPA--CDPGYQPTPGGGCQDVDECRNRSF-CG 993
+D++EC + C NT GS+ C A C+PGY G C+DVDEC + C
Sbjct: 718 EDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYA-LKDGECEDVDECAMGTHTCQ 776
Query: 994 AHAVCQNLPGSFQCL----CDQGYEGARDGRHCVDVNECETLQGVCGAAL-CENVEGSFL 1048
+CQN GSF C C G+ +G +CVD+NEC +L C C N GS+
Sbjct: 777 PGFLCQNTKGSFYCQARQRCMDGFLQDPEG-NCVDINECTSLSEPCRPGFSCINTVGSYT 835
Query: 1049 C-----VCPNSPEEFDPMTGRCVPPRT-SAGTFPGSQPQAPASPVLPARPPPPPLPRRPS 1102
C +C D T +CV G + Q + LP
Sbjct: 836 CQRNPLICARGYHASDDGT-KCVDVNECETGVHRCGEGQVCHN-----------LP---- 879
Query: 1103 TPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQ--CPGTE 1160
GS R +C + + C V E W S R+ Q C T
Sbjct: 880 -------GSYRCDCKAGF-----------QRDAFGRGCIDVNECWASPGRLCQHTCENT- 920
Query: 1161 TAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYY 1220
Y+ C G LA G DV+EC+ R C S C N Y CYC GY
Sbjct: 921 LGSYRCSCASGF-LLAADGKRC--EDVNECEAQR---C-SQECANIYGSYQCYCRQGYQL 973
Query: 1221 HTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTC-EPPLVLDGSQRRC 1269
C D DECA RC+N GSY C C E + + R C
Sbjct: 974 AEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSC 1023
Score = 83.2 bits (204), Expect = 2e-15
Identities = 142/577 (24%), Positives = 196/577 (33%), Gaps = 143/577 (24%)
Query: 853 DVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCE 912
D D S + +S +T E C G + D CL++ E +QR
Sbjct: 420 DTDPNSVHSIPRSSPEGSTKDLIETCCAAGQQWAIDNDECLEIPESGTEDNVCRTAQR-- 477
Query: 913 NSPGSYRCVRDCDPGYHAGPEG-TC--DDVDEC----QEYGPEICG--------AQRCEN 957
+ SY + C G EG TC +D D C + + CG Q CE+
Sbjct: 478 HCCVSYLQEKSCMAGVLGAKEGETCGAEDNDSCGISLYKQCCDCCGLGLRVRAEGQSCES 537
Query: 958 TPG-SYRCTP---ACDPGYQPT----------PGGGCQDVDEC----RNRSFCGAHAVCQ 999
P Y C +C G +P P + V E R G A
Sbjct: 538 NPNLGYPCNHVMLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALSLGTEAELP 597
Query: 1000 N-LPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVC-PNSPEE 1057
N LPG D +EC L G LC N GS+ C C P +
Sbjct: 598 NSLPGD-------------------DQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQ 638
Query: 1058 FDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPAR-------PPPPPLPRRPSTPRQGP-- 1108
D T C P G P QP+AP P L + P PLP+ + GP
Sbjct: 639 DDGRT--CRPE----GHPP--QPEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCK 690
Query: 1109 -----VGSGR--------------------RECYFDT---AAPDACDNILARNVTWQECC 1140
VG EC D + + C N L ++
Sbjct: 691 QVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALT 750
Query: 1141 CTVGEGWGSG-CR-IQQCP-GTETAEYQSLCPHGRGYLA--------------PSGDLSL 1183
C G G C + +C GT T + LC + +G P G+
Sbjct: 751 CEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCV- 809
Query: 1184 RRDVDECQLFRDQVCKSGV-CVNTAPGYSCY-----CSNGYYYHTQRLECIDNDECADEE 1237
D++EC + C+ G C+NT Y+C C+ GY+ +C+D +EC
Sbjct: 810 --DINECTSLSEP-CRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGV 866
Query: 1238 PAC-EGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSH 1296
C EG C N GSY C C+ D R C+ ++ CW G +C H
Sbjct: 867 HRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCI---------DVNECWASPGR--LCQH 915
Query: 1297 PRLDRQATYTECCCLYGEAWGMDCALCPAQDSDDFEA 1333
+ +Y C C G D C +D ++ EA
Sbjct: 916 TCENTLGSY-RCSCASGFLLAADGKRC--EDVNECEA 949
Score = 53.5 bits (127), Expect = 2e-06
Identities = 32/96 (33%), Positives = 42/96 (43%), Gaps = 11/96 (11%)
Query: 1456 GSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAE 1515
G E E EA+ C + C + + C C GY+L C DI+EC A+
Sbjct: 938 GKRCEDVNECEAQRC-------SQECANIYGSYQCYCRQGYQLAEDGHTCTDIDEC--AQ 988
Query: 1516 AASPLCVNARCLNTDGSFRCIC-RPGFAPTHQPHHC 1550
A LC RCLN GS++C C G+ T C
Sbjct: 989 GAGILC-TFRCLNVPGSYQCACPEQGYTMTANGRSC 1023
Score = 52.0 bits (123), Expect = 4e-06
Identities = 50/179 (27%), Positives = 69/179 (38%), Gaps = 20/179 (11%)
Query: 176 PWEEADAEAVARAEAAARAEAAAPYTVLAQSAPREDGYSDASGFGYCFRELRGGECASPL 235
P EA E ++E + A P + P+ + D + G S
Sbjct: 651 PQPEAPQEPALKSEFSQVASNTIPLPL-----PQPNTCKDNGPCKQVCSTVGGSAICSCF 705
Query: 236 PG--LRTQEVCCRGAG-LAWGVHDC---QLCSERLGNSERVSAPDGPCPTGFERVNGSCE 289
PG + V C +H C + C LG+ A C G+ +G CE
Sbjct: 706 PGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALT--CEPGYALKDGECE 763
Query: 290 DVDECATGGR-CQHG-ECANTRGGYTCV----CPDGFLLDSSRSSCISQHVISEAKGPC 342
DVDECA G CQ G C NT+G + C C DGFL D +C+ + + PC
Sbjct: 764 DVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQD-PEGNCVDINECTSLSEPC 821
Score = 49.7 bits (117), Expect = 2e-05
Identities = 28/69 (40%), Positives = 37/69 (53%), Gaps = 8/69 (11%)
Query: 1476 CTNGR-CVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASP--LCVNARCLNTDGS 1532
C G+ C +P + C C G++ D C+D+NEC ASP LC + C NT GS
Sbjct: 869 CGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNEC----WASPGRLCQHT-CENTLGS 923
Query: 1533 FRCICRPGF 1541
+RC C GF
Sbjct: 924 YRCSCASGF 932
Score = 49.3 bits (116), Expect = 3e-05
Identities = 36/84 (42%), Positives = 41/84 (48%), Gaps = 14/84 (16%)
Query: 253 GVHDC---QLCSERLGNSERVSAPDGPCPTGFER--VNGSCEDVDEC-ATGGR-CQHGEC 305
GVH C Q+C L S R C GF+R C DV+EC A+ GR CQH C
Sbjct: 865 GVHRCGEGQVC-HNLPGSYRCD-----CKAGFQRDAFGRGCIDVNECWASPGRLCQH-TC 917
Query: 306 ANTRGGYTCVCPDGFLLDSSRSSC 329
NT G Y C C GFLL + C
Sbjct: 918 ENTLGSYRCSCASGFLLAADGKRC 941
Score = 47.8 bits (112), Expect = 8e-05
Identities = 74/321 (23%), Positives = 116/321 (36%), Gaps = 64/321 (19%)
Query: 85 LCPLICHNGGVCVKPDRCLCPPDFA----GKFCQLHSSGARPPAPAVPGLTRSVYTMPLA 140
LC +C N V C C P F+ G+ C+ +P AP P L +S ++ +
Sbjct: 615 LCQHLCIN---TVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPAL-KSEFSQVAS 670
Query: 141 NHRDDEHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAEAAARAEAAAPY 200
N ++ + PQ + + +GP ++ + +A Y
Sbjct: 671 N------------TIPLPLPQPNTC------KDNGPCKQV----CSTVGGSAICSCFPGY 708
Query: 201 TVLAQSAPRED------GYSDASGFGYCFRELRGGECASPL---PGLRTQEVCCRGAG-L 250
++A ED S +C L C L PG ++ C
Sbjct: 709 AIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYALKDGECEDVDEC 768
Query: 251 AWGVHDCQ---LCSERLGNSERVSAPDGPCPTGF-ERVNGSCEDVDECATGGR-CQHG-E 304
A G H CQ LC G+ + C GF + G+C D++EC + C+ G
Sbjct: 769 AMGTHTCQPGFLCQNTKGSFYCQARQR--CMDGFLQDPEGNCVDINECTSLSEPCRPGFS 826
Query: 305 CANTRGGYTC-----VCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNI 359
C NT G YTC +C G+ + C+ ++E + R C N+
Sbjct: 827 CINTVGSYTCQRNPLICARGYHASDDGTKCVD---VNECETGVHRCGEGQVC-----HNL 878
Query: 360 TKQICCCSRVG---KAWGRGC 377
C + G A+GRGC
Sbjct: 879 PGSYRCDCKAGFQRDAFGRGC 899
Score = 46.2 bits (108), Expect = 2e-04
Identities = 32/103 (31%), Positives = 45/103 (43%), Gaps = 16/103 (15%)
Query: 1452 GSYAGSLAEPYEELE-AEECGILDGCTNG-------RCVRVPEGFTCRCFD-GYRLDMTR 1502
GSY + Y+ E C +D C G RC+ VP + C C + GY +
Sbjct: 961 GSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANG 1020
Query: 1503 MACVDINECDEAEAASPLCVNAR-CLNTDGSFRCI---CRPGF 1541
+C D++EC + C A C N GSFRC+ C P +
Sbjct: 1021 RSCKDVDEC---ALGTHNCSEAETCHNIQGSFRCLRFECPPNY 1060
Score = 45.8 bits (107), Expect = 3e-04
Identities = 27/88 (30%), Positives = 37/88 (42%), Gaps = 9/88 (10%)
Query: 1465 LEAEECGILDG--CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCV 1522
++ EC G C + C + C C G+ L C D+NEC EA+ S
Sbjct: 900 IDVNECWASPGRLCQH-TCENTLGSYRCSCASGFLLAADGKRCEDVNEC-EAQRCSQ--- 954
Query: 1523 NARCLNTDGSFRCICRPGFAPTHQPHHC 1550
C N GS++C CR G+ H C
Sbjct: 955 --ECANIYGSYQCYCRQGYQLAEDGHTC 980
Score = 45.1 bits (105), Expect = 5e-04
Identities = 34/109 (31%), Positives = 41/109 (37%), Gaps = 12/109 (11%)
Query: 1443 PEPEEPPEGG-----SYAGSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYR 1497
P+PE P E S S P + C C C V C CF GY
Sbjct: 651 PQPEAPQEPALKSEFSQVASNTIPLPLPQPNTCKDNGPCKQV-CSTVGGSAICSCFPGYA 709
Query: 1498 LDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRC----ICRPGFA 1542
+ ++C DINEC C+NT GSF C C PG+A
Sbjct: 710 IMADGVSCEDINEC--VTDLHTCSRGEHCVNTLGSFHCYKALTCEPGYA 756
Score = 44.7 bits (104), Expect = 7e-04
Identities = 36/115 (31%), Positives = 44/115 (38%), Gaps = 22/115 (19%)
Query: 1454 YAGSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTC-------------RCFDGYRLDM 1500
Y EP L+ EC +D C G P GF C RC DG+ D
Sbjct: 746 YKALTCEPGYALKDGECEDVDECAMGTHTCQP-GFLCQNTKGSFYCQARQRCMDGFLQD- 803
Query: 1501 TRMACVDINECDEAEAASPLCVNARCLNTDGSFRC-----ICRPGFAPTHQPHHC 1550
CVDINEC + P C+NT GS+ C IC G+ + C
Sbjct: 804 PEGNCVDINEC--TSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKC 856
Score = 43.1 bits (100), Expect = 0.002
Identities = 28/85 (32%), Positives = 38/85 (44%), Gaps = 11/85 (12%)
Query: 1465 LEAEECGIL-DGCTNG-RCVRVPEGFTCR-----CFDGYRLDMTRMACVDINECDEAEAA 1517
++ EC L + C G C+ +TC+ C GY CVD+NEC E
Sbjct: 809 VDINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGTKCVDVNEC---ETG 865
Query: 1518 SPLCVNAR-CLNTDGSFRCICRPGF 1541
C + C N GS+RC C+ GF
Sbjct: 866 VHRCGEGQVCHNLPGSYRCDCKAGF 890
Score = 41.6 bits (96), Expect = 0.006
Identities = 38/127 (29%), Positives = 46/127 (36%), Gaps = 20/127 (15%)
Query: 257 CQLCSERLGNSERVSAPDGPCPTGFERVNGS--CEDVDECATGGRCQHGECANTRGGYTC 314
CQ E S R S C +GF CEDV+EC RC ECAN G Y C
Sbjct: 913 CQHTCENTLGSYRCS-----CASGFLLAADGKRCEDVNECEAQ-RCSQ-ECANIYGSYQC 965
Query: 315 VCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVG---K 371
C G+ L +C ++ G C+ L C C G
Sbjct: 966 YCRQGYQLAEDGHTCTDIDECAQGAGIL--------CTFRCLNVPGSYQCACPEQGYTMT 1017
Query: 372 AWGRGCQ 378
A GR C+
Sbjct: 1018 ANGRSCK 1024
Score = 36.2 bits (82), Expect = 0.25
Identities = 32/96 (33%), Positives = 47/96 (48%), Gaps = 23/96 (23%)
Query: 244 CCRGAGLAWGVHDCQLCSERLGN---SERVSAPDGPCPTGFERV-NG-SCEDVDECATG- 297
C +GAG+ LC+ R N S + + P+ G+ NG SC+DVDECA G
Sbjct: 986 CAQGAGI--------LCTFRCLNVPGSYQCACPE----QGYTMTANGRSCKDVDECALGT 1033
Query: 298 GRCQHGE-CANTRGGYTCV---CPDGFLLDSSRSSC 329
C E C N +G + C+ CP + + S++ C
Sbjct: 1034 HNCSEAETCHNIQGSFRCLRFECPPNY-VQVSKTKC 1068
Score = 35.8 bits (81), Expect = 0.33
Identities = 19/43 (44%), Positives = 21/43 (48%), Gaps = 3/43 (6%)
Query: 289 EDVDECAT--GGRCQHGECANTRGGYTCVCPDGFLLDSSRSSC 329
+D DEC G CQH C NT G Y C C GF L +C
Sbjct: 603 DDQDECLLLPGELCQH-LCINTVGSYHCACFPGFSLQDDGRTC 644
Score = 32.3 bits (72), Expect = 3.7
Identities = 12/27 (44%), Positives = 15/27 (55%)
Query: 1526 CLNTDGSFRCICRPGFAPTHQPHHCAP 1552
C+NT GS+ C C PGF+ C P
Sbjct: 620 CINTVGSYHCACFPGFSLQDDGRTCRP 646
>gi|55770876 notch4 preproprotein [Homo sapiens]
Length = 2003
Score = 265 bits (677), Expect = 3e-70
Identities = 324/1161 (27%), Positives = 421/1161 (36%), Gaps = 281/1161 (24%)
Query: 449 PRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGP----------------- 491
PR + R GP P T +PE + +C P GP
Sbjct: 229 PRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNG 288
Query: 492 GRCISRPSGYTCACDSGFRLSPQGTRCI-DVDECR-RVPPPCA-PGRCENSPGSFRCVCG 548
G C YTC C + G C DVDEC + PP C G C+NS GSF CVC
Sbjct: 289 GTCQDGLDTYTCLCPETW----TGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCV 344
Query: 549 PGFRAGPRAAECLD-------------VDE----------------CHR----VPPPC-D 574
G+ G E LD +D CH + PC
Sbjct: 345 SGW-GGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHG 403
Query: 575 LGRCENTP--GSFLCVCPAGYQAAPHGASC-QDVDEC---TQSPGLCGR-GACKNLPGSF 627
+C P GS LC+C GY G +C QD+DEC Q P C G+C N PGSF
Sbjct: 404 DAQCSTNPLTGSTLCLCQPGYS----GPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSF 459
Query: 628 RCVCPAGFRGSACEEDVDECAQEPPPCGPG-RCDNTAGSFHCACPAGFRSRGPGAPCQ-D 685
C+CP G+ GS CE D +EC + PC PG C + +FHC CP G G C+ +
Sbjct: 460 NCLCPPGYTGSRCEADHNECLSQ--PCHPGSTCLDLLATFHCLCPPGLE----GQLCEVE 513
Query: 686 VDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSEC-EDVDECENHLACPGQECVN 744
+ECA S P + C + FQC+C GF +G+ C ED+DEC + G +C +
Sbjct: 514 TNECA-SAPCLNHADCHDLLNGFQCICLPGF----SGTRCEEDIDECRSSPCANGGQCQD 568
Query: 745 SPGSFQCRTCPSGHHLHRGRC-TDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPS 803
PG+F C+ P RC T+VDEC S PC C + G+F C C PS
Sbjct: 569 QPGAFHCKCLPG---FEGPRCQTEVDECLS--DPCPVGASCLDLPGAFFCLC------PS 617
Query: 804 GRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLC 863
G G +V C + C P C + C C G PG D C+ C
Sbjct: 618 GFTGQLCEVPLCAP-NLCQPKQICKDQKDKANCLCPDG-SPG----CAPPEDNCT----C 667
Query: 864 QSGICTNTDGSFECICPPGHRAGP----DLASCLDVDECRERGPALCGSQRCENSPGSYR 919
G C + C+C G GP +L C+ C G C P Y
Sbjct: 668 HHGHCQRS----SCVCDVGW-TGPECEAELGGCISA-PCAHGG-------TCYPQPSGYN 714
Query: 920 CVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGG 979
C C GY GP TC + GP + G C +PG Y CT C P + G
Sbjct: 715 CT--CPTGY-TGP--TCSEEMTACHSGPCLNGGS-CNPSPGGYYCT--CPPSH---TGPQ 763
Query: 980 CQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECE-TLQGVCGAA 1038
CQ + + C C N PG+F CLC G++G R CE L+ C +
Sbjct: 764 CQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPR----------CEGKLRPSCADS 813
Query: 1039 LCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLP 1098
C N C +SP+ RC+ P G + L P P
Sbjct: 814 PCRN-----RATCQDSPQ-----GPRCLCPTGYTG---------GSCQTLMDLCAQKPCP 854
Query: 1099 RRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPG 1158
R + GP S C P C+ L+ + Q+ + G S C
Sbjct: 855 RNSHCLQTGP--SFHCLCLQGWTGP-LCNLPLS---SCQKAALSQGIDVSSLCHNGGLCV 908
Query: 1159 TETAEYQSLCPHGRGYLAPSGDLSLRRD-VDECQLFRDQVCKSG-VCVNTAPGYSCYCSN 1216
Y CP P SL +D V+ C+ + C++G C+ GY C C+
Sbjct: 909 DSGPSYFCHCP-------PGFQGSLCQDHVNPCE---SRPCQNGATCMAQPSGYLCQCAP 958
Query: 1217 GYYYHTQRLECIDNDECADEEPACEG------GRCVNTVGSYHCTCEPPLVLDGSQRRCV 1270
GY D C+ E AC+ G C G +HC C P V RC
Sbjct: 959 GY----------DGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFV----GLRCE 1004
Query: 1271 SNESQSLDD--------------NLGVC---------WQEVGADLVCSHPRLDRQATYTE 1307
+ + LD N C W EV D S P
Sbjct: 1005 GDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQP---------- 1054
Query: 1308 CCCLYGEAWGMDCALCPAQDSDDFEALCNV---LRPPAYSPPRPG-GFGLPYEYGPDLGP 1363
C +G C A +C+ P S P GF + G L
Sbjct: 1055 --CFHG-------GTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPS 1105
Query: 1364 PYQGLP---------YGPELYPPPALPYDPYPPPP--------------GPFARREAPYG 1400
P G P GP+ PPA P PP P GP R P+
Sbjct: 1106 PKPGFPPRCACLSGYGGPDCLTPPA-PKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHS 1164
Query: 1401 A--PRFDMPDFEDDGGPYGESEAPAP-PGPGTRWPYRSRDTRRSFPEPEEPPEGGSYAGS 1457
+ PR P + G G+ A GPG W D P+P + S
Sbjct: 1165 SPGPRCQKPGAKGCEGRSGDGACDAGCSGPGGNWD--GGDCSLGVPDPWKGCPSHSRCWL 1222
Query: 1458 L---AEPYEELEAEECGILDG 1475
L + + + ++EEC + DG
Sbjct: 1223 LFRDGQCHPQCDSEEC-LFDG 1242
Score = 254 bits (650), Expect = 3e-67
Identities = 260/879 (29%), Positives = 344/879 (39%), Gaps = 207/879 (23%)
Query: 477 PSSGMCQRNPQVCGPG-RCISRPSGY-TCACDSGFRLSPQGTRCIDVDECRRVPPPCAPG 534
P +C P+ C G C+S G TC C GF G C D C+ G
Sbjct: 23 PRGLLCGSFPEPCANGGTCLSLSLGQGTCQCAPGFL----GETCQFPDPCQNAQLCQNGG 78
Query: 535 RCE----------NSPG----SFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDL-GRCE 579
C+ +SP SF C C PGF G R L+ D C P C GRC
Sbjct: 79 SCQALLPAPLGLPSSPSPLTPSFLCTCLPGF-TGERCQAKLE-DPCP--PSFCSKRGRCH 134
Query: 580 -NTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGS 638
G C C G+ G CQ D C+ +P + G G C +C CP GF G
Sbjct: 135 IQASGRPQCSCMPGWT----GEQCQLRDFCSANPCVNG-GVCLATYPQIQCHCPPGFEGH 189
Query: 639 ACEEDVDECAQEPPPCGPG-RCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCT 697
ACE DV+EC Q+P PC G C NT GSF C CP G Q+ C PC
Sbjct: 190 ACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVG----------QEGPRCELRAGPCP 239
Query: 698 YGRCEN---------TEGSFQ-CVCPMGFQPNTAGSECE-DVDECENHLACPGQECVNSP 746
C N + +F C+CP GF G +CE + D C +H G C +
Sbjct: 240 PRGCSNGGTCQLMPEKDSTFHLCLCPPGF----IGPDCEVNPDNCVSHQCQNGGTCQDGL 295
Query: 747 GSFQCRTCP---SGHHLHRGRCTDVDECSSGAPP-CGPHGHCTNTEGSFRCSCAPGYRAP 802
++ C CP +G DVDEC + PP C G C N+ GSF C C G+
Sbjct: 296 DTYTC-LCPETWTGWDCSE----DVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGT 350
Query: 803 SGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDL 862
S ++++C+ C P C++ GSF+C C PG R G C ED+
Sbjct: 351 SCE----ENLDDCIAAT-CAPGSTCIDRVGSFSCLCPPG-RTGLL---------CHLEDM 395
Query: 863 CQSGIC-------TN-TDGSFECICPPGHRAGPDLASCLDVDEC--RERGPALC-GSQRC 911
C S C TN GS C+C PG+ +GP D+DEC ++GP+ C C
Sbjct: 396 CLSQPCHGDAQCSTNPLTGSTLCLCQPGY-SGPTCHQ--DLDECLMAQQGPSPCEHGGSC 452
Query: 912 ENSPGSYRCVRDCDPGYHAG---------------PEGTCDDV--------------DEC 942
N+PGS+ C+ C PGY P TC D+ C
Sbjct: 453 LNTPGSFNCL--CPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLC 510
Query: 943 QEYGPEICGA-----QRCENTPGSYRCTPACDPGYQPTPGGGC-QDVDECRNRSFCGAHA 996
+ E A C + ++C C PG+ G C +D+DECR+ S C
Sbjct: 511 EVETNECASAPCLNHADCHDLLNGFQC--ICLPGFS---GTRCEEDIDECRS-SPCANGG 564
Query: 997 VCQNLPGSFQCLCDQGYEGARDGRHC-VDVNECETLQGVCGAALCENVEGSFLCVCPNSP 1055
CQ+ PG+F C C G+EG R C +V+EC + GA+ C ++ G+F C+CP+
Sbjct: 565 QCQDQPGAFHCKCLPGFEGPR----CQTEVDECLSDPCPVGAS-CLDLPGAFFCLCPSG- 618
Query: 1056 EEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRE 1115
F G + P +P ++ P GS
Sbjct: 619 -------------------FTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSP--- 656
Query: 1116 CYFDTAAPDACDNILARNVTWQECCCTVGEGWG--------SGCRIQQCP--GT---ETA 1162
A P+ DN + Q C GW GC C GT + +
Sbjct: 657 ---GCAPPE--DNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPS 711
Query: 1163 EYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHT 1222
Y CP GY P+ + C SG C+N G SC S G YY T
Sbjct: 712 GYNCTCP--TGYTGPTCSEEM------------TACHSGPCLN---GGSCNPSPGGYYCT 754
Query: 1223 -----QRLECIDNDECADEEPACEGGRCVNTVGSYHCTC 1256
+C + + P GG CVN G++ C C
Sbjct: 755 CPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLC 793
Score = 229 bits (585), Expect = 1e-59
Identities = 302/1150 (26%), Positives = 405/1150 (35%), Gaps = 285/1150 (24%)
Query: 228 GGECASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPD----GPCPTGFER 283
GG C GL T C W CSE + E P G C
Sbjct: 288 GGTCQD---GLDTYTCLCPETWTGWD------CSEDVDECETQGPPHCRNGGTCQNSAGS 338
Query: 284 VNGSC----------EDVDECATGGRCQHGECANTRGGYTCVCPDG--FLLDSSRSSCIS 331
+ C E++D+C C + G ++C+CP G LL C+S
Sbjct: 339 FHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLS 398
Query: 332 QHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAW----------GRGCQLCP 381
Q PC D CS L T +C G +G C
Sbjct: 399 Q--------PCH---GDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCE 447
Query: 382 PFGS-----EGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAG 436
GS F +CP PGY S + +N LSQP +T
Sbjct: 448 HGGSCLNTPGSFNCLCP--PGYTGSRCEADHNE----------CLSQPCHPGST---CLD 492
Query: 437 FLPT-HRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCI 495
L T H L P PG E +C+ C C+
Sbjct: 493 LLATFHCLCP---------PGLE--------------------GQLCEVETNECASAPCL 523
Query: 496 SRP------SGYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCA-PGRCENSPGSFRCVC 547
+ +G+ C C GF GTRC D+DECR PCA G+C++ PG+F C C
Sbjct: 524 NHADCHDLLNGFQCICLPGF----SGTRCEEDIDECR--SSPCANGGQCQDQPGAFHCKC 577
Query: 548 GPGFRAGPRAAECLDVDECHRVPPPCDLG-RCENTPGSFLCVCPAGYQ--------AAPH 598
PGF GPR +VDEC + PC +G C + PG+F C+CP+G+ AP+
Sbjct: 578 LPGFE-GPRCQ--TEVDEC--LSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPN 632
Query: 599 GAS----CQD-------------------VDECTQSPGLCGR------------------ 617
C+D D CT G C R
Sbjct: 633 LCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAEL 692
Query: 618 -----------GACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSF 666
G C P + C CP G+ G C E++ C P G G C+ + G +
Sbjct: 693 GGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNG-GSCNPSPGGY 751
Query: 667 HCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQ-PNTAGS-- 723
+C CP G CQ + S P G C N G+F C+C MGFQ P G
Sbjct: 752 YCTCPPSH----TGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLR 807
Query: 724 -ECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRC-TDVDECSSGAPPCGPH 781
C D C N C +SP +C CP+G+ G C T +D C+ PC +
Sbjct: 808 PSCAD-SPCRNRATCQ-----DSPQGPRC-LCPTGY--TGGSCQTLMDLCAQ--KPCPRN 856
Query: 782 GHCTNTEGSFRCSCAPGYRAP-SGRPGPCADVNECLEG----DFCFPHGECLNTDGSFAC 836
HC T SF C C G+ P P +G C G C+++ S+ C
Sbjct: 857 SHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFC 916
Query: 837 TCAPGYRPGPRGASCLDVDECSEEDLCQSG-ICTNTDGSFECICPPGHRAGPDLASCLDV 895
C PG+ +G+ C D E CQ+G C + C C PG+ D
Sbjct: 917 HCPPGF----QGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGY----------DG 962
Query: 896 DECRERGPALCGSQRCEN------SPGSYRCVRDCDPGY-HAGPEGTCDDVDECQEYGPE 948
C + A C SQ C N PG + C C PG+ EG DVDEC +
Sbjct: 963 QNCSKELDA-CQSQPCHNHGTCTPKPGGFHCA--CPPGFVGLRCEG---DVDECLDQPCH 1016
Query: 949 ICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQ-DVDECRNRSFCGAHAVCQNLPGS--- 1004
G C + ++ C C PG+ G C+ ++D C ++ C C+ GS
Sbjct: 1017 PTGTAACHSLANAFYC--QCLPGH---TGQWCEVEIDPCHSQP-CFHGGTCEATAGSPLG 1070
Query: 1005 FQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGR 1064
F C C +G+EG C CG C + LC+ P+ F P R
Sbjct: 1071 FICHCPKGFEGP----------TCSHRAPSCGFHHCHH---GGLCL-PSPKPGFPP---R 1113
Query: 1065 CVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSG-RRECYFDTAAP 1123
C + G P +P PP P L + G G G R C + P
Sbjct: 1114 C----ACLSGYGGPDCLTPPAP-KGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGP 1168
Query: 1124 DACDNILARNVTWQE----C---CCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLA 1176
C A+ + C C G W G C ++ H R +L
Sbjct: 1169 -RCQKPGAKGCEGRSGDGACDAGCSGPGGNWDGG----DCSLGVPDPWKGCPSHSRCWLL 1223
Query: 1177 -PSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECAD 1235
G + D +EC LF C++ P Y YC + ++H E C
Sbjct: 1224 FRDGQCHPQCDSEEC-LFDGYDCETPPA--CTPAYDQYCHD--HFHNGHCE----KGCNT 1274
Query: 1236 EEPACEGGRC 1245
E +GG C
Sbjct: 1275 AECGWDGGDC 1284
Score = 229 bits (584), Expect = 2e-59
Identities = 241/830 (29%), Positives = 343/830 (41%), Gaps = 152/830 (18%)
Query: 277 CPTGFERVNGSCEDVDECATGGRCQHG-ECANTRGGYTCVCPDGFLLDSSRSSCISQHVI 335
CP GF + CE + +CQ+G C + YTC+CP+ + + C
Sbjct: 264 CPPGF--IGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETW----TGWDCSEDVDE 317
Query: 336 SEAKGP-----------------CFRVLRDGGCSLP------ILRNITKQICCCSRVGKA 372
E +GP C V GG S I C RVG
Sbjct: 318 CETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSF 377
Query: 373 WGRGCQLCPPFGSEG----FREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLP 428
C LCPP G G ++C + P + D + +T PL + L Q P
Sbjct: 378 ---SC-LCPP-GRTGLLCHLEDMCLSQPCH----GDAQCSTNPL--TGSTLCLCQ----P 422
Query: 429 ATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSI------PAWTGPEIPESGPSSGMC 482
S P+ L + P P G L P P +TG C
Sbjct: 423 GYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCE---ADHNEC 479
Query: 483 QRNPQVCGPG-RCISRPSGYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCA-PGRCENS 539
P C PG C+ + + C C G +G C ++ +EC PC C +
Sbjct: 480 LSQP--CHPGSTCLDLLATFHCLCPPGL----EGQLCEVETNEC--ASAPCLNHADCHDL 531
Query: 540 PGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHG 599
F+C+C PGF +G R E D+DEC R P + G+C++ PG+F C C G++ G
Sbjct: 532 LNGFQCICLPGF-SGTRCEE--DIDEC-RSSPCANGGQCQDQPGAFHCKCLPGFE----G 583
Query: 600 ASCQ-DVDECTQSPGLCGRGA-CKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPG 657
CQ +VDEC P C GA C +LPG+F C+CP+GF G CE V CA P C P
Sbjct: 584 PRCQTEVDECLSDP--CPVGASCLDLPGAFFCLCPSGFTGQLCE--VPLCA--PNLCQPK 637
Query: 658 R-CDNTAGSFHCACPAGFRSRGPG-APCQDVDECARSPPPCTYGRCENTEGSFQCVCPMG 715
+ C + +C CP G PG AP + D C C +G C+ + CVC +G
Sbjct: 638 QICKDQKDKANCLCPDG----SPGCAPPE--DNCT-----CHHGHCQRS----SCVCDVG 682
Query: 716 FQPNTAGSECE-DVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCT-DVDECSS 773
+ G ECE ++ C + G C P + C TCP+G+ C+ ++ C S
Sbjct: 683 W----TGPECEAELGGCISAPCAHGGTCYPQPSGYNC-TCPTGY--TGPTCSEEMTACHS 735
Query: 774 GAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGS 833
G PC G C + G + C+C P + P C + CF G C+N G+
Sbjct: 736 G--PCLNGGSCNPSPGGYYCTCPPSHTGPQ-----CQTSTDYCVSAPCFNGGTCVNRPGT 788
Query: 834 FACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCL 893
F+C CA G++ GPR L C++ C ++ C+CP G+ G SC
Sbjct: 789 FSCLCAMGFQ-GPRCEGKLR-PSCADSPCRNRATCQDSPQGPRCLCPTGYTGG----SCQ 842
Query: 894 DVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCD-DVDECQEYG------ 946
+ + + P S + P S+ C+ C G+ GP C+ + CQ+
Sbjct: 843 TLMDLCAQKPCPRNSHCLQTGP-SFHCL--CLQGW-TGP--LCNLPLSSCQKAALSQGID 896
Query: 947 -PEIC-GAQRCENTPGSYRCTPACDPGYQPTPGGGCQD-VDECRNRSFCGAHAVCQNLPG 1003
+C C ++ SY C C PG+Q G CQD V+ C +R C A C P
Sbjct: 897 VSSLCHNGGLCVDSGPSYFC--HCPPGFQ---GSLCQDHVNPCESRP-CQNGATCMAQPS 950
Query: 1004 SFQCLCDQGYEGARDGRHC-VDVNECETLQGVCGAALCENVEGSFLCVCP 1052
+ C C GY DG++C +++ C++ Q C G F C CP
Sbjct: 951 GYLCQCAPGY----DGQNCSKELDACQS-QPCHNHGTCTPKPGGFHCACP 995
Score = 176 bits (446), Expect = 2e-43
Identities = 263/1022 (25%), Positives = 355/1022 (34%), Gaps = 185/1022 (18%)
Query: 608 CTQSPGLCGRGA-CKNLP-GSFRCVCPAGFRGSACE-----EDVDEC-------AQEPPP 653
C P C G C +L G C C GF G C+ ++ C A P P
Sbjct: 28 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAP 87
Query: 654 CG-PGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTY-GRCE-NTEGSFQC 710
G P SF C C GF G CQ E P C+ GRC G QC
Sbjct: 88 LGLPSSPSPLTPSFLCTCLPGFT----GERCQAKLEDPCPPSFCSKRGRCHIQASGRPQC 143
Query: 711 VCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDE 770
C P G +C+ D C + G C+ + QC CP G H DV+E
Sbjct: 144 SC----MPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCH-CPPGFEGHACE-RDVNE 197
Query: 771 CSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSG--RPGPCADVNECLEGDFCFPHGECL 828
C PC C NT GSF+C C G P R GPC C G C E
Sbjct: 198 CFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPP-RGCSNGGTCQLMPE-- 254
Query: 829 NTDGSF-ACTCAPGYRPGPRGASC-LDVDECSEEDLCQSGICTNTDGSFECICPPGHRAG 886
D +F C C PG+ G C ++ D C G C + ++ C+CP G
Sbjct: 255 -KDSTFHLCLCPPGFI----GPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETW-TG 308
Query: 887 PDLASCLDVDECRERGPALC-GSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEY 945
D + DVDEC +GP C C+NS GS+ CV C G+ G +++D+C
Sbjct: 309 WDCSE--DVDECETQGPPHCRNGGTCQNSAGSFHCV--CVSGW--GGTSCEENLDDC--I 360
Query: 946 GPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLP--G 1003
C + GS+ C C PG G C D C ++ C A C P G
Sbjct: 361 AATCAPGSTCIDRVGSFSCL--CPPG---RTGLLCHLEDMCLSQP-CHGDAQCSTNPLTG 414
Query: 1004 SFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCE------NVEGSFLCVCPNSPEE 1057
S CLC GY G + D++EC L G + CE N GSF C+C
Sbjct: 415 STLCLCQPGYSGPTCHQ---DLDEC--LMAQQGPSPCEHGGSCLNTPGSFNCLC------ 463
Query: 1058 FDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECY 1117
PP + GS+ +A EC
Sbjct: 464 ---------PPG-----YTGSRCEAD-----------------------------HNECL 480
Query: 1118 FDTAAPDA-CDNILARNVTWQECCCTVG-EGWGSGCRIQQCPGTETAEYQSLCPHGRGY- 1174
P + C ++LA C C G EG +C + G+
Sbjct: 481 SQPCHPGSTCLDLLATF----HCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQ 536
Query: 1175 ---LAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPG-YSCYCSNGYYYHTQRLECIDN 1230
L D+DEC R C +G PG + C C G+ + E
Sbjct: 537 CICLPGFSGTRCEEDIDEC---RSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEV--- 590
Query: 1231 DECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRR---CVSNESQSLDDNLGVCW-Q 1286
DEC + P G C++ G++ C C P G C N Q +C Q
Sbjct: 591 DECLSD-PCPVGASCLDLPGAFFCLC--PSGFTGQLCEVPLCAPNLCQPKQ----ICKDQ 643
Query: 1287 EVGADLVCSHPRLDRQATYTECCCLYGEAWGMDCALCPAQDSDDFEALCN--VLRPPAYS 1344
+ A+ +C C C +G C + EA + P A+
Sbjct: 644 KDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHG 703
Query: 1345 P---PRPGGFGL--PYEY-GPDLGPPYQGLPYGPELY-----PPPALPYDPYPPP-PGPF 1392
P+P G+ P Y GP GP L P P Y PP GP
Sbjct: 704 GTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQ 763
Query: 1393 ARREAPY--GAPRFDMPDFEDDGGPYGESEAPAPPGPGTRW---------PYRSRDTRRS 1441
+ Y AP F+ + G + A GP P R+R T +
Sbjct: 764 CQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQD 823
Query: 1442 FPEPEEPPEGGSYAGSLAEPYEELEAEECGILDGCT-NGRCVRVPEGFTCRCFDGYRLDM 1500
P+ Y G + +L A++ C N C++ F C C G+ +
Sbjct: 824 SPQGPRCLCPTGYTGGSCQTLMDLCAQK-----PCPRNSHCLQTGPSFHCLCLQGWTGPL 878
Query: 1501 TRMACVDINECDEAEAA-----SPLCVNAR-CLNTDGSFRCICRPGFAPTHQPHHCAPAR 1554
+ ++ C +A + S LC N C+++ S+ C C PGF + H P
Sbjct: 879 CNLP---LSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCE 935
Query: 1555 PR 1556
R
Sbjct: 936 SR 937
Score = 166 bits (420), Expect = 2e-40
Identities = 211/786 (26%), Positives = 281/786 (35%), Gaps = 178/786 (22%)
Query: 277 CPTGFERVNGSCEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLD------SSRSSCI 330
C GFE E VDEC + C + G + C+CP GF + + C
Sbjct: 577 CLPGFEGPRCQTE-VDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQ 635
Query: 331 SQHVISEAKGPCFRVLRDG--GCSLPILRNITKQICCCSRVGKAWGRGCQLCPP--FGSE 386
+ + + K + DG GC+ P + C C G C +C G E
Sbjct: 636 PKQICKDQKDKANCLCPDGSPGCAPP------EDNCTCHH-GHCQRSSC-VCDVGWTGPE 687
Query: 387 GFREI--CPAGPGYHYSA---SDLRYN-TRPLGQEPPRVSLSQPRTLPATSRPSAGFLPT 440
E+ C + P H YN T P G P S T+ S L
Sbjct: 688 CEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEM------TACHSGPCLNG 741
Query: 441 HRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSG 500
P P G P P+ TGP+ S + C P G G C++RP
Sbjct: 742 GSCNPSPG-------GYYCTCP--PSHTGPQCQTS---TDYCVSAPCFNG-GTCVNRPGT 788
Query: 501 YTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCEN------SPGSFRCVCGPGFRAG 554
++C C GF QG RC ++ P CA C N SP RC+C G+ G
Sbjct: 789 FSCLCAMGF----QGPRCEG-----KLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGG 839
Query: 555 --------------PRAAECLDVDECHR-------VPPPCDL------------------ 575
PR + CL P C+L
Sbjct: 840 SCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSS 899
Query: 576 -----GRCENTPGSFLCVCPAGYQAAPHGASCQD-VDECTQSPGLCGRGA-CKNLPGSFR 628
G C ++ S+ C CP G+Q G+ CQD V+ C P C GA C P +
Sbjct: 900 LCHNGGLCVDSGPSYFCHCPPGFQ----GSLCQDHVNPCESRP--CQNGATCMAQPSGYL 953
Query: 629 CVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQ-DVD 687
C C G+ G C +++D C Q P G C G FHCACP GF G C+ DVD
Sbjct: 954 CQCAPGYDGQNCSKELDAC-QSQPCHNHGTCTPKPGGFHCACPPGF----VGLRCEGDVD 1008
Query: 688 ECARSP-PPCTYGRCENTEGSFQCVCPMGFQPNTAGSECE-DVDECENHLACPGQECVNS 745
EC P P C + +F C C P G CE ++D C + G C +
Sbjct: 1009 ECLDQPCHPTGTAACHSLANAFYCQC----LPGHTGQWCEVEIDPCHSQPCFHGGTCEAT 1064
Query: 746 PGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHC-------TNTEGSF--RCSCA 796
GS P G H + + CS AP CG H HC + + F RC+C
Sbjct: 1065 AGS------PLGFICHCPKGFEGPTCSHRAPSCGFH-HCHHGGLCLPSPKPGFPPRCACL 1117
Query: 797 PGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDG----SFACTCAPGYRPGPR----G 848
GY P P C C +G C T G F C+C P PGPR G
Sbjct: 1118 SGYGGPDCLTPPAP--KGCGPPSPCLYNGSCSETTGLGGPGFRCSC-PHSSPGPRCQKPG 1174
Query: 849 ASCLDVDECSEEDLCQSGICTNTDGSFE---CIC--PPGHRAGPDLASC----------- 892
A + S + C +G C+ G+++ C P + P + C
Sbjct: 1175 AK--GCEGRSGDGACDAG-CSGPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDGQCHP 1231
Query: 893 -LDVDECRERG-----PALCG---SQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQ 943
D +EC G P C Q C + + C + C+ G C D
Sbjct: 1232 QCDSEECLFDGYDCETPPACTPAYDQYCHDHFHNGHCEKGCNTAECGWDGGDCRPEDGDP 1291
Query: 944 EYGPEI 949
E+GP +
Sbjct: 1292 EWGPSL 1297
Score = 40.0 bits (92), Expect = 0.018
Identities = 76/305 (24%), Positives = 100/305 (32%), Gaps = 84/305 (27%)
Query: 82 RAFLC---PLICHNGGVCVK----PDRCLCPPDFAGKFCQLHSSGARPPAPAVPGLTRSV 134
R LC P C NGG C+ C C P F G+ CQ G +++
Sbjct: 24 RGLLCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQAL 83
Query: 135 YTMPLANHRDDEHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAEAAARA 194
PL G+ S S P S + + +G A+
Sbjct: 84 LPAPL--------GLPSSPS-----PLTPSFLCTCLPGFTGE------------RCQAKL 118
Query: 195 EAAAPYTVLAQSAPREDGYSDASGFGYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGV 254
E P + ++ G C + G S +PG W
Sbjct: 119 EDPCPPSFCSKR-------------GRCHIQASGRPQCSCMPG--------------WTG 151
Query: 255 HDCQL---CSERLGNSERVSAPDGP-----CPTGFERVNGSCE-DVDECATG-GRCQHG- 303
CQL CS + V P CP GFE +CE DV+EC G C G
Sbjct: 152 EQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFE--GHACERDVNECFQDPGPCPKGT 209
Query: 304 ECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPC-FRVLRDGG-CSLPILRNITK 361
C NT G + C+CP G C GPC R +GG C L ++ T
Sbjct: 210 SCHNTLGSFQCLCPVG----QEGPRC------ELRAGPCPPRGCSNGGTCQLMPEKDSTF 259
Query: 362 QICCC 366
+C C
Sbjct: 260 HLCLC 264
Score = 38.9 bits (89), Expect = 0.039
Identities = 16/31 (51%), Positives = 18/31 (58%), Gaps = 3/31 (9%)
Query: 89 ICHNGGVCVKPDR---CLCPPDFAGKFCQLH 116
+CHNGG+CV C CPP F G CQ H
Sbjct: 900 LCHNGGLCVDSGPSYFCHCPPGFQGSLCQDH 930
Score = 38.1 bits (87), Expect = 0.067
Identities = 72/301 (23%), Positives = 90/301 (29%), Gaps = 73/301 (24%)
Query: 45 CVHGPTGSRCTPTCAPRNATSVDSGAPGGAAPGG------PGFRAFLCPLI--------C 90
C G GS C P + +GA A P G PG+ C C
Sbjct: 918 CPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPC 977
Query: 91 HNGGVCV-KPD--RCLCPPDFAGKFCQ----------LHSSGARPPAPAVPGLTRSVYTM 137
HN G C KP C CPP F G C+ H +G A L + Y
Sbjct: 978 HNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTG----TAACHSLANAFYCQ 1033
Query: 138 PLANHRDDEHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAEAAARAEAA 197
L H G V + H Q + EA A +
Sbjct: 1034 CLPGHT----GQWCEVEIDPCHSQPC-------------FHGGTCEATAGSPLGFICHCP 1076
Query: 198 APYTVLAQSAPREDGYSDASGFGYCFRELRGGEC-ASPLPGLRTQEVCCRGAGLAWGVHD 256
+ P + + GF +C GG C SP PG + C G +G D
Sbjct: 1077 KGF-----EGPTCSHRAPSCGFHHCH---HGGLCLPSPKPGFPPRCACLSG----YGGPD 1124
Query: 257 CQLCSERLGNSERVSAPDGPCPTGFERVNGSCEDVDECATGGRCQHGECANTRGGYTCVC 316
C G P PC NGSC + GG C ++ G C
Sbjct: 1125 CLTPPAPKG-----CGPPSPC-----LYNGSCSET--TGLGGPGFRCSCPHSSPGPRCQK 1172
Query: 317 P 317
P
Sbjct: 1173 P 1173
Score = 37.7 bits (86), Expect = 0.087
Identities = 22/70 (31%), Positives = 28/70 (40%), Gaps = 14/70 (20%)
Query: 1476 CTNGR-CVRVPEGFTCRCFDGYRLDMTRMACVDINECD---EAEAASPLCVNARCLNTDG 1531
C NG C+ P G+ C+C GY D C +A + P + C G
Sbjct: 939 CQNGATCMAQPSGYLCQCAPGY----------DGQNCSKELDACQSQPCHNHGTCTPKPG 988
Query: 1532 SFRCICRPGF 1541
F C C PGF
Sbjct: 989 GFHCACPPGF 998
Score = 36.6 bits (83), Expect = 0.19
Identities = 29/88 (32%), Positives = 35/88 (39%), Gaps = 18/88 (20%)
Query: 45 CVHGPTGSRCTPT---------CAPRNATSVD-SGAPG-GAAPGGPG----FRAFLCPLI 89
C+ G TG RC C+ R + SG P PG G R F
Sbjct: 105 CLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFCSANP 164
Query: 90 CHNGGVCVKPD---RCLCPPDFAGKFCQ 114
C NGGVC+ +C CPP F G C+
Sbjct: 165 CVNGGVCLATYPQIQCHCPPGFEGHACE 192
Score = 34.3 bits (77), Expect = 0.96
Identities = 28/109 (25%), Positives = 39/109 (35%), Gaps = 25/109 (22%)
Query: 44 RCVHGPTGSRCTPTCAPRNATSVDSGAPGGAAPGGP---------GFRAFLCPLI----- 89
+C+ G TG C P ++ G A G P GF C
Sbjct: 1033 QCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCG 1092
Query: 90 ---CHNGGVCVK------PDRCLCPPDFAGKFCQLHSS--GARPPAPAV 127
CH+GG+C+ P RC C + G C + G PP+P +
Sbjct: 1093 FHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCL 1141
Score = 32.7 bits (73), Expect = 2.8
Identities = 15/37 (40%), Positives = 21/37 (56%), Gaps = 7/37 (18%)
Query: 87 PLICHNGGVC-VKPDR------CLCPPDFAGKFCQLH 116
P C NGG C + P++ CLCPP F G C+++
Sbjct: 240 PRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVN 276
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 246 bits (627), Expect = 2e-64
Identities = 150/429 (34%), Positives = 203/429 (47%), Gaps = 57/429 (13%)
Query: 631 CPAGFR----GSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDV 686
CP+GF G C ++ DECA P C C N G+++C+CP G G CQD+
Sbjct: 5092 CPSGFTLDSVGPFCADE-DECAAGNP-CSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDI 5148
Query: 687 DECARSPPPCTYGR-CENTEGSFQCV--CPMGFQPNTAGSECEDVDECENHLACPGQECV 743
DECA C G+ C+NT GS++CV C GF+ + G C+D++EC+ C Q C
Sbjct: 5149 DECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCH-QRCF 5207
Query: 744 NSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPS 803
N+ GSF C C G+ L +C DV+EC C P HC NT G ++C
Sbjct: 5208 NAIGSFHCG-CEPGYQLKGRKCMDVNECRQNV--CRPDQHCKNTRGGYKCIDLCPNGMTK 5264
Query: 804 GRPGPCADVNECLEGDF-CFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDL 862
G C D++EC +G C + C NT GS+ C C GYR G C+D++EC +
Sbjct: 5265 AENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPK 5324
Query: 863 CQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSP------- 915
+ C+NT GSF+CICPPG D SC ++ G SP
Sbjct: 5325 PCAHQCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRNNYQP 5384
Query: 916 -----------GSY--------------RCVRDCDPGYHAGPEGTCDDVDECQEYGPEIC 950
SY R +R P TC D+DEC+ + C
Sbjct: 5385 QQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHDTCVDIDECE--NTDAC 5442
Query: 951 GAQRCENTPGSYRCTPACDPGYQPTPGG-GCQDVDECRNRS-FCGAHAVCQNLPGSFQCL 1008
C+NT GSY+C C PGYQ T G CQD+DEC ++ CG + +C N+ GS+QC+
Sbjct: 5443 -QHECKNTFGSYQC--ICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCI 5499
Query: 1009 ---CDQGYE 1014
C Y+
Sbjct: 5500 DTPCPPNYQ 5508
Score = 244 bits (623), Expect = 5e-64
Identities = 159/441 (36%), Positives = 203/441 (46%), Gaps = 68/441 (15%)
Query: 589 CPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFR----GSACEEDV 644
CP+G+ G C D DEC C +C N G++ C CP G G C+ D+
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAG-NPCSH-SCHNAMGTYYCSCPKGLTIAADGRTCQ-DI 5148
Query: 645 DECAQEPPPCGPGR-CDNTAGSFHCA--CPAGFRSRGPGAPCQDVDECARSPPPCTYGRC 701
DECA C G+ CDNT GS+ C C +GFR G CQD++EC S P + RC
Sbjct: 5149 DECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSP--CHQRC 5206
Query: 702 ENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQC-RTCPSGH-H 759
N GSF C C G+Q G +C DV+EC ++ P Q C N+ G ++C CP+G
Sbjct: 5207 FNAIGSFHCGCEPGYQ--LKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTK 5264
Query: 760 LHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGD 819
G C D+DEC G C + C NT GS+RC C GYR+ G PC D+NEC +
Sbjct: 5265 AENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRS-QGVGRPCMDINECEQVP 5323
Query: 820 FCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVD-------ECSEEDLCQSGICTN-- 870
H +C NT GSF C C PG G SC ++ + S +L + N
Sbjct: 5324 KPCAH-QCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRNNY 5382
Query: 871 ----------------------------TDGSFECICPPGHRAGPDLASCLDVDECRERG 902
T + CP G A D +C+D+DEC
Sbjct: 5383 QPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHD--TCVDIDECENTD 5440
Query: 903 PALCGSQRCENSPGSYRCVRDCDPGYHAGPEG-TCDDVDECQEYGPEICGAQR-CENTPG 960
C+N+ GSY+C+ C PGY G TC D+DEC E CG R C N G
Sbjct: 5441 AC---QHECKNTFGSYQCI--CPPGYQLTHNGKTCQDIDECLEQNVH-CGPNRMCFNMRG 5494
Query: 961 SYRC--TPACDPGYQPTPGGG 979
SY+C TP C P YQ P G
Sbjct: 5495 SYQCIDTP-CPPNYQRDPVSG 5514
Score = 235 bits (599), Expect = 3e-61
Identities = 145/443 (32%), Positives = 206/443 (46%), Gaps = 63/443 (14%)
Query: 670 CPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVD 729
CP+GF G C D DECA P C++ C N G++ C CP G G C+D+D
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAGNP-CSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDID 5149
Query: 730 ECE--NHLACPGQECVNSPGSFQCRT-CPSGHHLHRG--RCTDVDECSSGAPPCGPHGHC 784
EC H GQ+C N+ GS++C C SG C D++EC +P C H C
Sbjct: 5150 ECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSP-C--HQRC 5206
Query: 785 TNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACT--CAPGY 842
N GSF C C PGY+ + C DVNEC + + C P C NT G + C C G
Sbjct: 5207 FNAIGSFHCGCEPGYQLKGRK---CMDVNECRQ-NVCRPDQHCKNTRGGYKCIDLCPNGM 5262
Query: 843 RPGPRGASCLDVDECSE--EDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRE 900
G +C+D+DEC + + IC NT GS+ C+CP G+R+ C+D++EC E
Sbjct: 5263 TKAENG-TCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINEC-E 5320
Query: 901 RGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEG-TCDDVDECQEYGPEICGAQRCENTP 959
+ P C Q C N+PGS++C+ C PG H +G +C ++ YG + +P
Sbjct: 5321 QVPKPCAHQ-CSNTPGSFKCI--CPPGQHLLGDGKSCAGLERLPNYGTQYSSYNLARFSP 5377
Query: 960 GSYRCTP---------------------------------ACDPGYQPTPGGGCQDVDEC 986
P C G + + C D+DEC
Sbjct: 5378 VRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHDT-CVDIDEC 5436
Query: 987 RNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGA-ALCENVEG 1045
N C C+N GS+QC+C GY+ +G+ C D++EC CG +C N+ G
Sbjct: 5437 ENTDACQHE--CKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRG 5494
Query: 1046 SFLCVCPNSPEEF--DPMTGRCV 1066
S+ C+ P + DP++G C+
Sbjct: 5495 SYQCIDTPCPPNYQRDPVSGFCL 5517
Score = 233 bits (593), Expect = 1e-60
Identities = 146/419 (34%), Positives = 191/419 (45%), Gaps = 64/419 (15%)
Query: 494 CISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGR-CENSPGSFRCV--CGPG 550
C + Y C+C G ++ G C D+DEC C G+ C+N+ GS+RCV CG G
Sbjct: 5121 CHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSG 5180
Query: 551 FRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQ 610
FR C D++EC PC RC N GSF C C GYQ G C DV+EC Q
Sbjct: 5181 FRRTSDGLSCQDINECQE-SSPCH-QRCFNAIGSFHCGCEPGYQL--KGRKCMDVNECRQ 5236
Query: 611 SPGLCGRGA-CKNLPGSFRCV--CPAGF---RGSACEEDVDECAQEPPPCGPGR-CDNTA 663
+ +C CKN G ++C+ CP G C D+DEC C + C+NT
Sbjct: 5237 N--VCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTC-IDIDECKDGTHQCRYNQICENTR 5293
Query: 664 GSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGS 723
GS+ C CP G+RS+G G PC D++EC + P PC + +C NT GSF+C+CP G G
Sbjct: 5294 GSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAH-QCSNTPGSFKCICPPGQHLLGDGK 5352
Query: 724 ECEDVDECEN------------------------------HLACPGQECVNSPGSFQ--- 750
C ++ N HL E NS S
Sbjct: 5353 SCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTR 5412
Query: 751 ---CRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPG 807
+TCP G C D+DEC + C C NT GS++C C PGY+ +
Sbjct: 5413 RTIRKTCPEGSEASHDTCVDIDECEN-TDAC--QHECKNTFGSYQCICPPGYQL-THNGK 5468
Query: 808 PCADVNECLEGD-FCFPHGECLNTDGSFAC---TCAPGYRPGPRGASCLDVDECSEEDL 862
C D++ECLE + C P+ C N GS+ C C P Y+ P CL C DL
Sbjct: 5469 TCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFCL--KNCPPNDL 5525
Score = 232 bits (592), Expect = 2e-60
Identities = 150/440 (34%), Positives = 203/440 (46%), Gaps = 65/440 (14%)
Query: 505 CDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVD 564
C SGF L G C D DEC PC+ C N+ G++ C C G C D+D
Sbjct: 5092 CPSGFTLDSVGPFCADEDEC-AAGNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDID 5149
Query: 565 ECHRVPPPCDLGR-CENTPGSFLCV--CPAGYQAAPHGASCQDVDECTQSPGLCGRGACK 621
EC C G+ C+NT GS+ CV C +G++ G SCQD++EC +S R C
Sbjct: 5150 ECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQR--CF 5207
Query: 622 NLPGSFRCVCPAGF--RGSACEEDVDECAQEPPPCGPGR-CDNTAGSFHC--ACPAGFRS 676
N GSF C C G+ +G C DV+EC Q C P + C NT G + C CP G +
Sbjct: 5208 NAIGSFHCGCEPGYQLKGRKC-MDVNECRQN--VCRPDQHCKNTRGGYKCIDLCPNGM-T 5263
Query: 677 RGPGAPCQDVDECARSPPPCTYGR-CENTEGSFQCVCPMGFQPNTAGSECEDVDECENHL 735
+ C D+DEC C Y + CENT GS++CVCP G++ G C D++ECE
Sbjct: 5264 KAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVP 5323
Query: 736 ACPGQECVNSPGSFQCRTCPSGHHL--HRGRCTDVDEC---------------------- 771
+C N+PGSF+C CP G HL C ++
Sbjct: 5324 KPCAHQCSNTPGSFKC-ICPPGQHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRNNY 5382
Query: 772 -------------SSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEG 818
SS + + T + R +C G A C D++EC
Sbjct: 5383 QPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASH---DTCVDIDECENT 5439
Query: 819 DFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDL-C-QSGICTNTDGSFE 876
D C EC NT GS+ C C PGY+ G +C D+DEC E+++ C + +C N GS++
Sbjct: 5440 DAC--QHECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQ 5497
Query: 877 CI---CPPGHRAGPDLASCL 893
CI CPP ++ P CL
Sbjct: 5498 CIDTPCPPNYQRDPVSGFCL 5517
Score = 226 bits (575), Expect = 2e-58
Identities = 157/440 (35%), Positives = 212/440 (48%), Gaps = 65/440 (14%)
Query: 547 CGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVD 606
C GF C D DEC PC C N G++ C CP G A G +CQD+D
Sbjct: 5092 CPSGFTLDSVGPFCADEDEC-AAGNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDID 5149
Query: 607 ECTQSPGLCGRGA-CKNLPGSFRCV--CPAGFR----GSACEEDVDECAQEPPPCGPGRC 659
EC C G C N GS+RCV C +GFR G +C+ D++EC QE PC RC
Sbjct: 5150 ECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQ-DINEC-QESSPCHQ-RC 5206
Query: 660 DNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGR-CENTEGSFQCV--CPMGF 716
N GSFHC C G++ +G C DV+EC ++ C + C+NT G ++C+ CP G
Sbjct: 5207 FNAIGSFHCGCEPGYQLKG--RKCMDVNECRQNV--CRPDQHCKNTRGGYKCIDLCPNGM 5262
Query: 717 QPNTAGSECEDVDECEN--HLACPGQECVNSPGSFQCRTCPSGHHLHR-GR-CTDVDECS 772
G+ C D+DEC++ H Q C N+ GS++C CP G+ GR C D++EC
Sbjct: 5263 TKAENGT-CIDIDECKDGTHQCRYNQICENTRGSYRC-VCPRGYRSQGVGRPCMDINECE 5320
Query: 773 SGAPPCGPHGHCTNTEGSFRCSCAPGY-------------RAPS----------GRPGPC 809
PC C+NT GSF+C C PG R P+ R P
Sbjct: 5321 QVPKPCAHQ--CSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPV 5378
Query: 810 ADVNECLEGDFCFPH-----GECLNTDGSFACTCAPGYRPGPRGA-----SCLDVDECSE 859
+ + + + H E N+ S + T + P G+ +C+D+DEC
Sbjct: 5379 RNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHDTCVDIDECEN 5438
Query: 860 EDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQR-CENSPGSY 918
D CQ C NT GS++CICPPG++ + +C D+DEC E+ CG R C N GSY
Sbjct: 5439 TDACQHE-CKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQN-VHCGPNRMCFNMRGSY 5496
Query: 919 RCV-RDCDPGYHAGP-EGTC 936
+C+ C P Y P G C
Sbjct: 5497 QCIDTPCPPNYQRDPVSGFC 5516
Score = 188 bits (478), Expect = 3e-47
Identities = 136/443 (30%), Positives = 193/443 (43%), Gaps = 37/443 (8%)
Query: 783 HCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGY 842
H + ++G C G+ S P CAD +EC G+ C C N G++ C+C G
Sbjct: 5080 HASISKGDRSNQCPSGFTLDSVGPF-CADEDECAAGNPC--SHSCHNAMGTYYCSCPKGL 5136
Query: 843 RPGPRGASCLDVDECS-EEDLCQSGI-CTNTDGSFECI--CPPGHRAGPDLASCLDVDEC 898
G +C D+DEC+ C +G C NT GS+ C+ C G R D SC D++EC
Sbjct: 5137 TIAADGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINEC 5196
Query: 899 RERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGA-QRCEN 957
+E P QRC N+ GS+ C C+PGY C DV+EC++ +C Q C+N
Sbjct: 5197 QESSPC---HQRCFNAIGSFHC--GCEPGYQLKGR-KCMDVNECRQ---NVCRPDQHCKN 5247
Query: 958 TPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSF-CGAHAVCQNLPGSFQCLCDQGYEGA 1016
T G Y+C C G G C D+DEC++ + C + +C+N GS++C+C +GY
Sbjct: 5248 TRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQ 5307
Query: 1017 RDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEF-DPMTGRCVPPRTSAGTF 1075
GR C+D+NECE + C A C N GSF C+CP D + + + GT
Sbjct: 5308 GVGRPCMDINECEQVPKPC-AHQCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQ 5366
Query: 1076 PGSQPQAPASPVLPARPPP------PPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNI 1129
S A SPV P L S R R P+ +
Sbjct: 5367 YSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSE-- 5424
Query: 1130 LARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDE 1189
+ C + E + +C T YQ +CP G L +G +D+DE
Sbjct: 5425 -----ASHDTCVDIDECENTDACQHECKNT-FGSYQCICPPGY-QLTHNGKTC--QDIDE 5475
Query: 1190 CQLFRDQVCKSGVCVNTAPGYSC 1212
C + +C N Y C
Sbjct: 5476 CLEQNVHCGPNRMCFNMRGSYQC 5498
Score = 161 bits (408), Expect = 4e-39
Identities = 103/330 (31%), Positives = 148/330 (44%), Gaps = 57/330 (17%)
Query: 493 RCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGR-CENSPGSFRCV--CGP 549
RC + + C C+ G++L +G +C+DV+ECR+ C P + C+N+ G ++C+ C
Sbjct: 5205 RCFNAIGSFHCGCEPGYQL--KGRKCMDVNECRQ--NVCRPDQHCKNTRGGYKCIDLCPN 5260
Query: 550 GFRAGPRAAECLDVDECHRVPPPCDLGR-CENTPGSFLCVCPAGYQAAPHGASCQDVDEC 608
G C+D+DEC C + CENT GS+ CVCP GY++ G C D++EC
Sbjct: 5261 GMTKAENGT-CIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINEC 5319
Query: 609 TQSPGLCGRGACKNLPGSFRCVCPAGFR----GSACE--EDVDECAQEPPPCGPGR---- 658
Q P C C N PGSF+C+CP G G +C E + + R
Sbjct: 5320 EQVPKPCAH-QCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPV 5378
Query: 659 -----------------------------CDNTAGSFHCACPAGFRSRGPGAPCQDVDEC 689
T + CP G S C D+DEC
Sbjct: 5379 RNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEG--SEASHDTCVDIDEC 5436
Query: 690 ARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDEC-ENHLAC-PGQECVNSPG 747
+ C + C+NT GS+QC+CP G+Q G C+D+DEC E ++ C P + C N G
Sbjct: 5437 -ENTDACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRG 5494
Query: 748 SFQCRTCPSGHHLHRGRCTDVDECSSGAPP 777
S+QC P + R + C PP
Sbjct: 5495 SYQCIDTPCPPNYQRDPVSGF--CLKNCPP 5522
Score = 160 bits (406), Expect = 7e-39
Identities = 138/470 (29%), Positives = 186/470 (39%), Gaps = 77/470 (16%)
Query: 838 CAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDE 897
C G+ G C D DEC+ + C S C N G++ C CP G D +C D+DE
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAGNPC-SHSCHNAMGTYYCSCPKGLTIAADGRTCQDIDE 5150
Query: 898 CRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEG-TCDDVDECQEYGPEICGAQRCE 956
C Q C+N+ GSYRCV C G+ +G +C D++ECQE P C QRC
Sbjct: 5151 CALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSP--CH-QRCF 5207
Query: 957 NTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQC--LCDQGYE 1014
N GS+ C C+PGYQ G C DV+ECR ++ C C+N G ++C LC G
Sbjct: 5208 NAIGSFHC--GCEPGYQ-LKGRKCMDVNECR-QNVCRPDQHCKNTRGGYKCIDLCPNGMT 5263
Query: 1015 GARDGRHCVDVNECETLQGVCGA-ALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAG 1073
A +G C+D++EC+ C +CEN GS+ RCV PR
Sbjct: 5264 KAENGT-CIDIDECKDGTHQCRYNQICENTRGSY----------------RCVCPRGYRS 5306
Query: 1074 TFPGSQPQAPASPVLPARPPPPPLPRRPST----------PRQGPVGSGRRECYFDTAAP 1123
G P + P P + S P Q +G G+ C P
Sbjct: 5307 QGVGR----PCMDINECEQVPKPCAHQCSNTPGSFKCICPPGQHLLGDGK-SCAGLERLP 5361
Query: 1124 DACDNILARNVT-----------------WQECCCTVGEGWGSGCRIQQCPGTETAEYQS 1166
+ + N+ + + E S + + T +
Sbjct: 5362 NYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRT----IRK 5417
Query: 1167 LCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLE 1226
CP G S D + D+DEC+ C+ C NT Y C C GY
Sbjct: 5418 TCPEGS---EASHDTCV--DIDECE--NTDACQHE-CKNTFGSYQCICPPGYQLTHNGKT 5469
Query: 1227 CIDNDECADEEPACEGGR-CVNTVGSYHC---TCEPPLVLDGSQRRCVSN 1272
C D DEC ++ C R C N GSY C C P D C+ N
Sbjct: 5470 CQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFCLKN 5519
Score = 145 bits (367), Expect = 2e-34
Identities = 94/290 (32%), Positives = 127/290 (43%), Gaps = 53/290 (18%)
Query: 482 CQRNPQVCGPGR-CISRPSGYTCA--CDSGFRLSPQGTRCIDVDECRRVPPPCAPGR-CE 537
C++N VC P + C + GY C C +G + GT CID+DEC+ C + CE
Sbjct: 5234 CRQN--VCRPDQHCKNTRGGYKCIDLCPNGMTKAENGT-CIDIDECKDGTHQCRYNQICE 5290
Query: 538 NSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAP 597
N+ GS+RCVC G+R+ C+D++EC +VP PC +C NTPGSF C+CP G
Sbjct: 5291 NTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPC-AHQCSNTPGSFKCICPPGQHLLG 5349
Query: 598 HGASCQDVDE------------------------------------CTQSPGLCGRGACK 621
G SC ++ + S R +
Sbjct: 5350 DGKSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLS 5409
Query: 622 NLPGSFRCVCPAGFRGS--ACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGP 679
+ R CP G S C D+DEC E C NT GS+ C CP G++
Sbjct: 5410 RTRRTIRKTCPEGSEASHDTC-VDIDEC--ENTDACQHECKNTFGSYQCICPPGYQLTHN 5466
Query: 680 GAPCQDVDECARSPPPCTYGR-CENTEGSFQCV---CPMGFQPNTAGSEC 725
G CQD+DEC C R C N GS+QC+ CP +Q + C
Sbjct: 5467 GKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFC 5516
Score = 87.4 bits (215), Expect = 1e-16
Identities = 88/327 (26%), Positives = 113/327 (34%), Gaps = 81/327 (24%)
Query: 968 CDPGYQ-PTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVN 1026
C G+ + G C D DEC + C +H+ C N G++ C C +G A DGR C D++
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAGNPC-SHS-CHNAMGTYYCSCPKGLTIAADGRTCQDID 5149
Query: 1027 ECETLQGVCGAAL-CENVEGSFLCVCP-----------------NSPEEFDPMTGRCVPP 1068
EC + C A C+N GS+ CV N +E P RC
Sbjct: 5150 ECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQRCFNA 5209
Query: 1069 RTS--AGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDAC 1126
S G PG Q +G EC + PD
Sbjct: 5210 IGSFHCGCEPGYQ-------------------------LKGRKCMDVNECRQNVCRPD-- 5242
Query: 1127 DNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRD 1186
Q C T G G C I CP T C D
Sbjct: 5243 ----------QHCKNTRG---GYKC-IDLCPNGMTKAENGTCI----------------D 5272
Query: 1187 VDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCV 1246
+DEC+ Q + +C NT Y C C GY C+D +EC C +C
Sbjct: 5273 IDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPC-AHQCS 5331
Query: 1247 NTVGSYHCTCEPPLVLDGSQRRCVSNE 1273
NT GS+ C C P L G + C E
Sbjct: 5332 NTPGSFKCICPPGQHLLGDGKSCAGLE 5358
Score = 75.5 bits (184), Expect = 4e-13
Identities = 60/221 (27%), Positives = 86/221 (38%), Gaps = 59/221 (26%)
Query: 482 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVP-----------PP 530
C++ P+ C +C + P + C C G L G C ++ R+P
Sbjct: 5319 CEQVPKPCAH-QCSNTPGSFKCICPPGQHLLGDGKSCAGLE---RLPNYGTQYSSYNLAR 5374
Query: 531 CAPGRCENSPG----------------------------SFRCVCGPGFRAGPRAAECLD 562
+P R P + R C G A C+D
Sbjct: 5375 FSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHDT--CVD 5432
Query: 563 VDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCG-RGACK 621
+DEC C C+NT GS+ C+CP GYQ +G +CQD+DEC + CG C
Sbjct: 5433 IDECENTDA-CQ-HECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCF 5490
Query: 622 NLPGSFRCV---CP--------AGFRGSACEEDVDECAQEP 651
N+ GS++C+ CP +GF C + ECA P
Sbjct: 5491 NMRGSYQCIDTPCPPNYQRDPVSGFCLKNCPPNDLECALSP 5531
Score = 73.6 bits (179), Expect = 1e-12
Identities = 93/364 (25%), Positives = 139/364 (38%), Gaps = 60/364 (16%)
Query: 254 VHDCQL---CSERLGNSERVSAPDGPCPTGFERVNGSCEDVDECATGGRCQHGECANTRG 310
+++CQ C +R N+ + + C G++ C DV+EC C NTRG
Sbjct: 5193 INECQESSPCHQRCFNA--IGSFHCGCEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRG 5250
Query: 311 GYTCV--CPDGFLLDSSRSSCIS-------------QHVISEAKGP----CFRVLRDGGC 351
GY C+ CP+G + + +CI + +G C R R G
Sbjct: 5251 GYKCIDLCPNG-MTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGV 5309
Query: 352 SLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREICPAGPGYHY-----SASDLR 406
P + I C +V K C P GS F+ ICP PG H S + L
Sbjct: 5310 GRPCM-----DINECEQVPKPCAHQCSNTP--GS--FKCICP--PGQHLLGDGKSCAGLE 5358
Query: 407 YNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPA 466
G + +L++ + +P + L + R +I
Sbjct: 5359 -RLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRK 5417
Query: 467 WTGPEIPESGPSSGM----CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVD 522
T PE E+ + + C+ N C C + Y C C G++L+ G C D+D
Sbjct: 5418 -TCPEGSEASHDTCVDIDECE-NTDAC-QHECKNTFGSYQCICPPGYQLTHNGKTCQDID 5474
Query: 523 ECRRVPPPCAPGR-CENSPGSFRCV---CGPGFRAGPRAAECLDVDECHRVPPPCDLGRC 578
EC C P R C N GS++C+ C P ++ P + CL C PP DL C
Sbjct: 5475 ECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFCL--KNC----PPNDL-EC 5527
Query: 579 ENTP 582
+P
Sbjct: 5528 ALSP 5531
Score = 51.2 bits (121), Expect = 8e-06
Identities = 28/79 (35%), Positives = 36/79 (45%), Gaps = 12/79 (15%)
Query: 1470 CGILDGCTNGR--------CVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLC 1521
C +D C +G C + C C GYR C+DINEC++ P
Sbjct: 5270 CIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQV----PKP 5325
Query: 1522 VNARCLNTDGSFRCICRPG 1540
+C NT GSF+CIC PG
Sbjct: 5326 CAHQCSNTPGSFKCICPPG 5344
Score = 50.1 bits (118), Expect = 2e-05
Identities = 23/55 (41%), Positives = 28/55 (50%), Gaps = 3/55 (5%)
Query: 277 CPTGF--ERVNGSCEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSC 329
CP+GF + V C D DECA G C H C N G Y C CP G + + +C
Sbjct: 5092 CPSGFTLDSVGPFCADEDECAAGNPCSH-SCHNAMGTYYCSCPKGLTIAADGRTC 5145
Score = 50.1 bits (118), Expect = 2e-05
Identities = 30/86 (34%), Positives = 39/86 (45%), Gaps = 15/86 (17%)
Query: 1466 EAEECGILDGCTNGR--------CVRVPEGFTC--RCFDGYRLDMTRMACVDINECDEAE 1515
+ C +D C GR C + C RC G+R ++C DINEC E
Sbjct: 5141 DGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQE-- 5198
Query: 1516 AASPLCVNARCLNTDGSFRCICRPGF 1541
+SP + RC N GSF C C PG+
Sbjct: 5199 -SSP--CHQRCFNAIGSFHCGCEPGY 5221
Score = 46.2 bits (108), Expect = 2e-04
Identities = 28/83 (33%), Positives = 39/83 (46%), Gaps = 13/83 (15%)
Query: 253 GVHDC---QLCSERLGNSERVSAPDGPCPTGF--ERVNGSCEDVDECATGGR-CQHGECA 306
G H C Q+C G+ V CP G+ + V C D++EC + C H +C+
Sbjct: 5279 GTHQCRYNQICENTRGSYRCV------CPRGYRSQGVGRPCMDINECEQVPKPCAH-QCS 5331
Query: 307 NTRGGYTCVCPDGFLLDSSRSSC 329
NT G + C+CP G L SC
Sbjct: 5332 NTPGSFKCICPPGQHLLGDGKSC 5354
Score = 45.4 bits (106), Expect = 4e-04
Identities = 20/46 (43%), Positives = 26/46 (56%), Gaps = 5/46 (10%)
Query: 1505 CVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHC 1550
CVDI+EC+ +A C NT GS++CIC PG+ TH C
Sbjct: 5430 CVDIDECENTDACQH-----ECKNTFGSYQCICPPGYQLTHNGKTC 5470
Score = 43.1 bits (100), Expect = 0.002
Identities = 28/85 (32%), Positives = 37/85 (43%), Gaps = 5/85 (5%)
Query: 1456 GSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAE 1515
GS A ++ +EC D C + C + C C GY+L C DI+EC E
Sbjct: 5422 GSEASHDTCVDIDECENTDACQH-ECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQN 5480
Query: 1516 A-ASPLCVNARCLNTDGSFRCICRP 1539
P N C N GS++CI P
Sbjct: 5481 VHCGP---NRMCFNMRGSYQCIDTP 5502
Score = 42.7 bits (99), Expect = 0.003
Identities = 27/72 (37%), Positives = 33/72 (45%), Gaps = 7/72 (9%)
Query: 277 CPTGFERV--NGSCEDVDECATGGRCQHG--ECANTRGGYTCV--CPDGFLLDSSRSSCI 330
CP G +C+D+DECA G H +C NT G Y CV C GF S SC
Sbjct: 5132 CPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQ 5191
Query: 331 SQHVISEAKGPC 342
+ E+ PC
Sbjct: 5192 DINECQES-SPC 5202
Score = 38.9 bits (89), Expect = 0.039
Identities = 26/91 (28%), Positives = 40/91 (43%), Gaps = 13/91 (14%)
Query: 1460 EPYEELEAEECGILDGCTNG------RCVRVPEGFTCRCFDGYRLDMTRM---ACVDINE 1510
EP +L+ +C ++ C C G+ +C D MT+ C+DI+E
Sbjct: 5218 EPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGY--KCIDLCPNGMTKAENGTCIDIDE 5275
Query: 1511 CDEAEAASPLCVNARCLNTDGSFRCICRPGF 1541
C + N C NT GS+RC+C G+
Sbjct: 5276 CKDG--THQCRYNQICENTRGSYRCVCPRGY 5304
Score = 38.1 bits (87), Expect = 0.067
Identities = 23/71 (32%), Positives = 33/71 (46%), Gaps = 7/71 (9%)
Query: 1466 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNAR 1525
+ EC C + RC F C C GY+L + C+D+NEC + P +
Sbjct: 5192 DINECQESSPC-HQRCFNAIGSFHCGCEPGYQLKGRK--CMDVNECRQ-NVCRP---DQH 5244
Query: 1526 CLNTDGSFRCI 1536
C NT G ++CI
Sbjct: 5245 CKNTRGGYKCI 5255
Score = 37.0 bits (84), Expect = 0.15
Identities = 25/87 (28%), Positives = 35/87 (40%), Gaps = 5/87 (5%)
Query: 1466 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNAR 1525
+ +EC + C++ C + C C G + C DI+EC A
Sbjct: 5107 DEDECAAGNPCSHS-CHNAMGTYYCSCPKGLTIAADGRTCQDIDEC--ALGRHTCHAGQD 5163
Query: 1526 CLNTDGSFRCI--CRPGFAPTHQPHHC 1550
C NT GS+RC+ C GF T C
Sbjct: 5164 CDNTIGSYRCVVRCGSGFRRTSDGLSC 5190
>gi|34734064 fibulin 1 isoform B precursor [Homo sapiens]
Length = 601
Score = 239 bits (611), Expect = 1e-62
Identities = 153/398 (38%), Positives = 205/398 (51%), Gaps = 41/398 (10%)
Query: 687 DECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDEC--ENHLACPGQECVN 744
D C R PC +C +T C C +G+Q + G CEDV+EC +H G+ C+N
Sbjct: 178 DRC-RGGGPCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCIN 235
Query: 745 SPGSFQCR---TCPSGHHLHRGR-CTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYR 800
+ GSF+C+ +C +G+ L C D+DEC SG C P C NT GSFRC P +
Sbjct: 236 TVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCR--PKLQ 293
Query: 801 APSG----RPGPCADVNECLEGDFCFPHGE-CLNTDGSFAC-----TCAPGYRPGPRGAS 850
SG G C D+NECL P G C+NT+GS+ C C GY G
Sbjct: 294 CKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTR 353
Query: 851 CLDVDECSEE-DLCQSGI-CTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGS 908
C+DVDEC+ + C G C N+ GSF C C G+ C+DV+EC+ LCG
Sbjct: 354 CVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCG- 412
Query: 909 QRCENSPGSYRCVRDCDPGYHAGPEG-TCDDVDECQEYGPEICGAQRCENTPGSYRCTPA 967
+CEN+ GSY C C G+ +G +C+D++EC C +Q C N GSY+C
Sbjct: 413 HKCENTLGSYLC--SCSVGFRLSVDGRSCEDINECSS---SPC-SQECANVYGSYQCY-- 464
Query: 968 CDPGYQPTPGGG--CQDVDECRNRSFCGAHAV---CQNLPGSFQCLC-DQGYEGARDGRH 1021
C GYQ + G C+D+DEC + G H C N+PGSFQC C GY A +GR+
Sbjct: 465 CRRGYQLSDVDGVTCEDIDECALPT--GGHICSYRCINIPGSFQCSCPSSGYRLAPNGRN 522
Query: 1022 CVDVNECETLQGVCGA-ALCENVEGSFLCVCPNSPEEF 1058
C D++EC T C C N++G F C+ PE +
Sbjct: 523 CQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENY 560
Score = 217 bits (553), Expect = 6e-56
Identities = 148/389 (38%), Positives = 193/389 (49%), Gaps = 41/389 (10%)
Query: 653 PCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGR-CENTEGSFQCV 711
PC +C +T C+C G++ G C+DV+EC C G C NT GSF+C
Sbjct: 185 PCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQ 243
Query: 712 ----CPMGFQPNTAGSECEDVDECEN--HLACPGQECVNSPGSFQCRT---CPSGHHLHR 762
C G++ T + C+D+DECE+ H P C N+ GSF+CR C SG
Sbjct: 244 RDSSCGTGYEL-TEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDA 302
Query: 763 -GRCTDVDECSSGAPPCGPHGH-CTNTEGSFRC-----SCAPGYRAPSGRPGPCADVNEC 815
G C D++EC S + PC P GH C NTEGS+ C +C GY + C DV+EC
Sbjct: 303 LGNCIDINECLSISAPC-PIGHTCINTEGSYTCQKNVPNCGRGYHL-NEEGTRCVDVDEC 360
Query: 816 LE-GDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEED--LCQSGICTNTD 872
+ C C+N+ GSF C C GY C+DV+EC LC C NT
Sbjct: 361 APPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHK-CENTL 419
Query: 873 GSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGP 932
GS+ C C G R D SC D++EC + C SQ C N GSY+C C GY
Sbjct: 420 GSYLCSCSVGFRLSVDGRSCEDINECSS---SPC-SQECANVYGSYQCY--CRRGYQLSD 473
Query: 933 EG--TCDDVDECQ-EYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGG-GCQDVDECRN 988
TC+D+DEC G IC + RC N PGS++C+ GY+ P G CQD+DEC
Sbjct: 474 VDGVTCEDIDECALPTGGHIC-SYRCINIPGSFQCS-CPSSGYRLAPNGRNCQDIDECVT 531
Query: 989 RSF-CGAHAVCQNLPGSFQCL---CDQGY 1013
C + C N+ G F+CL C + Y
Sbjct: 532 GIHNCSINETCFNIQGGFRCLAFECPENY 560
Score = 217 bits (552), Expect = 8e-56
Identities = 153/423 (36%), Positives = 204/423 (48%), Gaps = 55/423 (13%)
Query: 606 DECTQSPGLCGRGACKNLPGSFRCVCPAGFR----GSACEEDVDECAQEPPPCGPGR-CD 660
D C + G C + C++ C C G++ G +CE DV+EC C G C
Sbjct: 178 DRC-RGGGPC-KQQCRDTGDEVVCSCFVGYQLLSDGVSCE-DVNECITGSHSCRLGESCI 234
Query: 661 NTAGSFHC----ACPAGFRSRGPGAPCQDVDECARSPPPCTYGR-CENTEGSFQC----V 711
NT GSF C +C G+ + C+D+DEC C C+NT GSF+C
Sbjct: 235 NTVGSFRCQRDSSCGTGYELTEDNS-CKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQ 293
Query: 712 CPMGFQPNTAGSECEDVDECENHLA-CP-GQECVNSPGSFQCR----TCPSGHHLHRG-- 763
C GF + G+ C D++EC + A CP G C+N+ GS+ C+ C G+HL+
Sbjct: 294 CKSGFIQDALGN-CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGT 352
Query: 764 RCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFP 823
RC DVDEC+ A PCG C N+ GSFRC C GY G C DVNEC
Sbjct: 353 RCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYF-DGISRMCVDVNECQRYPGRLC 411
Query: 824 HGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGH 883
+C NT GS+ C+C+ G+R G SC D++ECS Q C N GS++C C G+
Sbjct: 412 GHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQE--CANVYGSYQCYCRRGY 469
Query: 884 R-AGPDLASCLDVDECR-ERGPALCGSQRCENSPGSYRCVRDC-DPGYHAGPEG-TCDDV 939
+ + D +C D+DEC G +C S RC N PGS++C C GY P G C D+
Sbjct: 470 QLSDVDGVTCEDIDECALPTGGHIC-SYRCINIPGSFQC--SCPSSGYRLAPNGRNCQDI 526
Query: 940 DECQEYGPEICGA-QRCENTPGSYRC--------------TPACDPGYQPTPGGGCQDVD 984
DEC G C + C N G +RC T G Q TP G + +
Sbjct: 527 DECVT-GIHNCSINETCFNIQGGFRCLAFECPENYRRSAATQKSKKGRQNTPAGSSK--E 583
Query: 985 ECR 987
+CR
Sbjct: 584 DCR 586
Score = 212 bits (539), Expect = 3e-54
Identities = 150/390 (38%), Positives = 189/390 (48%), Gaps = 48/390 (12%)
Query: 490 GPGRCISRPSG--YTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGR-CENSPGSFRCV 546
GP + R +G C+C G++L G C DV+EC C G C N+ GSFRC
Sbjct: 184 GPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQ 243
Query: 547 ----CGPGFRAGPRAAECLDVDECHRVPPPC--DLGRCENTPGSFLC----VCPAGYQAA 596
CG G+ C D+DEC C D C+NT GSF C C +G+
Sbjct: 244 RDSSCGTGYEL-TEDNSCKDIDECESGIHNCLPDF-ICQNTLGSFRCRPKLQCKSGFIQD 301
Query: 597 PHGASCQDVDECTQSPGLCGRG-ACKNLPGSFRCV-----CPAGFR----GSACEEDVDE 646
G +C D++EC C G C N GS+ C C G+ G+ C DVDE
Sbjct: 302 ALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCV-DVDE 359
Query: 647 CAQEPPPCGPG-RCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTE 705
CA PCG G RC N+ GSF C C G+ G C DV+EC R P +CENT
Sbjct: 360 CAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTL 419
Query: 706 GSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHL---HR 762
GS+ C C +GF+ + G CED++EC + QEC N GS+QC C G+ L
Sbjct: 420 GSYLCSCSVGFRLSVDGRSCEDINECSSSPC--SQECANVYGSYQC-YCRRGYQLSDVDG 476
Query: 763 GRCTDVDECSSGAPPCGPH---GHCTNTEGSFRCSC-APGYR-APSGRPGPCADVNECLE 817
C D+DEC A P G H C N GSF+CSC + GYR AP+GR C D++EC+
Sbjct: 477 VTCEDIDEC---ALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGR--NCQDIDECVT 531
Query: 818 G-DFCFPHGECLNTDGSFAC---TCAPGYR 843
G C + C N G F C C YR
Sbjct: 532 GIHNCSINETCFNIQGGFRCLAFECPENYR 561
Score = 195 bits (496), Expect = 3e-49
Identities = 133/360 (36%), Positives = 176/360 (48%), Gaps = 37/360 (10%)
Query: 729 DECENHLACPGQECVNSPGSFQCRTCPSGHHLHRG--RCTDVDECSSGAPPCGPHGHCTN 786
D C C Q+C ++ C +C G+ L C DV+EC +G+ C C N
Sbjct: 178 DRCRGGGPCK-QQCRDTGDEVVC-SCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCIN 235
Query: 787 TEGSFRC----SCAPGYRAPSGRPGPCADVNECLEGDF-CFPHGECLNTDGSFACT---- 837
T GSFRC SC GY C D++EC G C P C NT GSF C
Sbjct: 236 TVGSFRCQRDSSCGTGYELTEDNS--CKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQ 293
Query: 838 CAPGYRPGPRGASCLDVDEC-SEEDLCQSG-ICTNTDGSFECI-----CPPGHRAGPDLA 890
C G+ G +C+D++EC S C G C NT+GS+ C C G+ +
Sbjct: 294 CKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGT 352
Query: 891 SCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHA-GPEGTCDDVDECQEYGPEI 949
C+DVDEC RC NSPGS+RC +C GY+ G C DV+ECQ Y +
Sbjct: 353 RCVDVDECAPPAEPCGKGHRCVNSPGSFRC--ECKTGYYFDGISRMCVDVNECQRYPGRL 410
Query: 950 CGAQRCENTPGSYRCTPACDPGYQ-PTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCL 1008
CG +CENT GSY C+ C G++ G C+D++EC + S C C N+ GS+QC
Sbjct: 411 CG-HKCENTLGSYLCS--CSVGFRLSVDGRSCEDINECSS-SPCSQE--CANVYGSYQCY 464
Query: 1009 CDQGYE-GARDGRHCVDVNECETLQG--VCGAALCENVEGSFLCVCPNSPEEFDPMTGRC 1065
C +GY+ DG C D++EC G +C + C N+ GSF C CP+S P C
Sbjct: 465 CRRGYQLSDVDGVTCEDIDECALPTGGHIC-SYRCINIPGSFQCSCPSSGYRLAPNGRNC 523
Score = 187 bits (474), Expect = 9e-47
Identities = 102/248 (41%), Positives = 138/248 (55%), Gaps = 27/248 (10%)
Query: 494 CISRPSGYTCA-----CDSGFRLSPQGTRCIDVDECRRVPPPCAPG-RCENSPGSFRCVC 547
CI+ YTC C G+ L+ +GTRC+DVDEC PC G RC NSPGSFRC C
Sbjct: 325 CINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCEC 384
Query: 548 GPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDE 607
G+ + C+DV+EC R P +CENT GS+LC C G++ + G SC+D++E
Sbjct: 385 KTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINE 444
Query: 608 CTQSPGLCGRGACKNLPGSFRCVCPAGFR-----GSACEEDVDECAQEPPPCG----PGR 658
C+ SP C + C N+ GS++C C G++ G C ED+DECA P G R
Sbjct: 445 CSSSP--CSQ-ECANVYGSYQCYCRRGYQLSDVDGVTC-EDIDECAL---PTGGHICSYR 497
Query: 659 CDNTAGSFHCACP-AGFRSRGPGAPCQDVDECARSPPPCTYGR-CENTEGSFQCV---CP 713
C N GSF C+CP +G+R G CQD+DEC C+ C N +G F+C+ CP
Sbjct: 498 CINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECP 557
Query: 714 MGFQPNTA 721
++ + A
Sbjct: 558 ENYRRSAA 565
Score = 118 bits (295), Expect = 5e-26
Identities = 70/180 (38%), Positives = 96/180 (53%), Gaps = 14/180 (7%)
Query: 482 CQRNP-QVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSP 540
CQR P ++CG +C + Y C+C GFRLS G C D++EC PC+ C N
Sbjct: 403 CQRYPGRLCGH-KCENTLGSYLCSCSVGFRLSVDGRSCEDINECS--SSPCSQ-ECANVY 458
Query: 541 GSFRCVCGPGFR-AGPRAAECLDVDECHRVPPPCDL--GRCENTPGSFLCVCP-AGYQAA 596
GS++C C G++ + C D+DEC +P + RC N PGSF C CP +GY+ A
Sbjct: 459 GSYQCYCRRGYQLSDVDGVTCEDIDEC-ALPTGGHICSYRCINIPGSFQCSCPSSGYRLA 517
Query: 597 PHGASCQDVDECTQSPGLCG-RGACKNLPGSFRCV---CPAGFRGSACEEDVDECAQEPP 652
P+G +CQD+DEC C C N+ G FRC+ CP +R SA + + Q P
Sbjct: 518 PNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATQKSKKGRQNTP 577
Score = 112 bits (279), Expect = 4e-24
Identities = 114/384 (29%), Positives = 146/384 (38%), Gaps = 75/384 (19%)
Query: 896 DECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEG-TCDDVDECQEYGPEICGAQR 954
D CR GP Q+C ++ C C GY +G +C+DV+EC +
Sbjct: 178 DRCRGGGPC---KQQCRDTGDEVVC--SCFVGYQLLSDGVSCEDVNECITGSHSCRLGES 232
Query: 955 CENTPGSYRCT--PACDPGYQPTPGGGCQDVDECRNRSF-CGAHAVCQNLPGSFQCL--- 1008
C NT GS+RC +C GY+ T C+D+DEC + C +CQN GSF+C
Sbjct: 233 CINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKL 292
Query: 1009 -CDQGYEGARDGRHCVDVNECETLQGVCGAA-LCENVEGSFLCV--CPNSPEEF--DPMT 1062
C G+ G +C+D+NEC ++ C C N EGS+ C PN + +
Sbjct: 293 QCKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEG 351
Query: 1063 GRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRREC----YF 1118
RCV A PP P GS R EC YF
Sbjct: 352 TRCVDVDECA---------------------PPAEPCGKGHRCVNSPGSFRCECKTGYYF 390
Query: 1119 DTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPS 1178
D I V EC G G C E LC G+ S
Sbjct: 391 D--------GISRMCVDVNECQRYPGRLCGHKC--------ENTLGSYLCSCSVGFRL-S 433
Query: 1179 GDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYY-HTQRLECIDNDECADEE 1237
D D++EC C S C N Y CYC GY + C D DECA
Sbjct: 434 VDGRSCEDINECS---SSPC-SQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECA--- 486
Query: 1238 PACEGG-----RCVNTVGSYHCTC 1256
GG RC+N GS+ C+C
Sbjct: 487 -LPTGGHICSYRCINIPGSFQCSC 509
Score = 70.9 bits (172), Expect = 9e-12
Identities = 48/146 (32%), Positives = 63/146 (43%), Gaps = 22/146 (15%)
Query: 1186 DVDECQLFRDQVCKSG-VCVNTAPGYSCY-----CSNGYYYHTQRLECIDNDECADE-EP 1238
D++EC L C G C+NT Y+C C GY+ + + C+D DECA EP
Sbjct: 308 DINEC-LSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEP 366
Query: 1239 ACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVS-NESQSLDDNLGVCWQEVGADLVCSHP 1297
+G RCVN+ GS+ C C+ DG R CV NE Q L C H
Sbjct: 367 CGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRL------------CGHK 414
Query: 1298 RLDRQATYTECCCLYGEAWGMDCALC 1323
+ +Y C C G +D C
Sbjct: 415 CENTLGSYL-CSCSVGFRLSVDGRSC 439
Score = 61.2 bits (147), Expect = 7e-09
Identities = 36/100 (36%), Positives = 46/100 (46%), Gaps = 3/100 (3%)
Query: 1171 GRGY-LAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECID 1229
GRGY L G + DVDEC + K CVN+ + C C GYY+ C+D
Sbjct: 342 GRGYHLNEEGTRCV--DVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVD 399
Query: 1230 NDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRC 1269
+EC G +C NT+GSY C+C L R C
Sbjct: 400 VNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSC 439
Score = 54.3 bits (129), Expect = 9e-07
Identities = 31/75 (41%), Positives = 34/75 (45%), Gaps = 8/75 (10%)
Query: 1467 AEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARC 1526
AE CG RCV P F C C GY D CVD+NEC LC +C
Sbjct: 364 AEPCG-----KGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGR--LC-GHKC 415
Query: 1527 LNTDGSFRCICRPGF 1541
NT GS+ C C GF
Sbjct: 416 ENTLGSYLCSCSVGF 430
Score = 52.4 bits (124), Expect = 3e-06
Identities = 30/84 (35%), Positives = 42/84 (50%), Gaps = 9/84 (10%)
Query: 1465 LEAEEC-GILDGCTNGR-CVRVPEGFTCR-----CFDGYRLDMTRMACVDINECDEAEAA 1517
++ EC I C G C+ +TC+ C GY L+ CVD++EC A A
Sbjct: 307 IDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDEC--APPA 364
Query: 1518 SPLCVNARCLNTDGSFRCICRPGF 1541
P RC+N+ GSFRC C+ G+
Sbjct: 365 EPCGKGHRCVNSPGSFRCECKTGY 388
Score = 47.8 bits (112), Expect = 8e-05
Identities = 26/78 (33%), Positives = 39/78 (50%), Gaps = 7/78 (8%)
Query: 1465 LEAEECGILDGCTNG-RCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 1523
++ EC G G +C + C C G+RL + +C DINEC ++SP +
Sbjct: 398 VDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINEC----SSSP--CS 451
Query: 1524 ARCLNTDGSFRCICRPGF 1541
C N GS++C CR G+
Sbjct: 452 QECANVYGSYQCYCRRGY 469
Score = 47.8 bits (112), Expect = 8e-05
Identities = 31/96 (32%), Positives = 41/96 (42%), Gaps = 13/96 (13%)
Query: 1452 GSYAGSLAEPYE--ELEAEECGILDGC---TNG-----RCVRVPEGFTCRC-FDGYRLDM 1500
GSY Y+ +++ C +D C T G RC+ +P F C C GYRL
Sbjct: 459 GSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAP 518
Query: 1501 TRMACVDINECDEAEAASPLCVNARCLNTDGSFRCI 1536
C DI+EC +N C N G FRC+
Sbjct: 519 NGRNCQDIDEC--VTGIHNCSINETCFNIQGGFRCL 552
Score = 46.2 bits (108), Expect = 2e-04
Identities = 27/77 (35%), Positives = 37/77 (48%), Gaps = 7/77 (9%)
Query: 1464 ELEAEECGILDGCTNG-----RCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAAS 1518
E E E+ + D C G +C + C CF GY+L ++C D+NEC +
Sbjct: 168 EEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSC 227
Query: 1519 PLCVNARCLNTDGSFRC 1535
L C+NT GSFRC
Sbjct: 228 RL--GESCINTVGSFRC 242
Score = 45.4 bits (106), Expect = 4e-04
Identities = 33/97 (34%), Positives = 45/97 (46%), Gaps = 11/97 (11%)
Query: 254 VHDCQLCSERLGNSER-VSAPDG---PCPTG--FERVNGSCEDVDECAT--GGRCQHGEC 305
V +C +E G R V++P C TG F+ ++ C DV+EC G C H +C
Sbjct: 357 VDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH-KC 415
Query: 306 ANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPC 342
NT G Y C C GF L SC + + + PC
Sbjct: 416 ENTLGSYLCSCSVGFRLSVDGRSC--EDINECSSSPC 450
Score = 45.4 bits (106), Expect = 4e-04
Identities = 28/92 (30%), Positives = 45/92 (48%), Gaps = 8/92 (8%)
Query: 1452 GSYAGSLAEPYE-ELEAEECGILDGCTNG----RCVRVPEGFTCRCFDGYRL-DMTRMAC 1505
GSY S + + ++ C ++ C++ C V + C C GY+L D+ + C
Sbjct: 420 GSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTC 479
Query: 1506 VDINECDEAEAASPLCVNARCLNTDGSFRCIC 1537
DI+EC +C + RC+N GSF+C C
Sbjct: 480 EDIDEC-ALPTGGHIC-SYRCINIPGSFQCSC 509
Score = 44.7 bits (104), Expect = 7e-04
Identities = 30/101 (29%), Positives = 45/101 (44%), Gaps = 13/101 (12%)
Query: 253 GVHDCQ---LCSERLGNSERVSAPDGPCPTGF-ERVNGSCEDVDECAT-GGRCQHGE-CA 306
G+H+C +C LG+ P C +GF + G+C D++EC + C G C
Sbjct: 269 GIHNCLPDFICQNTLGSFR--CRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCI 326
Query: 307 NTRGGYTCV-----CPDGFLLDSSRSSCISQHVISEAKGPC 342
NT G YTC C G+ L+ + C+ + PC
Sbjct: 327 NTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPC 367
Score = 43.5 bits (101), Expect = 0.002
Identities = 31/100 (31%), Positives = 44/100 (44%), Gaps = 13/100 (13%)
Query: 253 GVHDCQL---CSERLGNSERVSAPDGPCPTGFERV-NGSCEDVDECATG--GRCQHGECA 306
G H C+L C +G+ D C TG+E + SC+D+DEC +G C
Sbjct: 223 GSHSCRLGESCINTVGSFR--CQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQ 280
Query: 307 NTRGGYTC----VCPDGFLLDSSRSSCISQHVISEAKGPC 342
NT G + C C GF+ D + +CI + PC
Sbjct: 281 NTLGSFRCRPKLQCKSGFIQD-ALGNCIDINECLSISAPC 319
Score = 41.6 bits (96), Expect = 0.006
Identities = 28/86 (32%), Positives = 36/86 (41%), Gaps = 15/86 (17%)
Query: 1462 YEELEAEECGILDGCTNGR--------CVRVPEGFTCR----CFDGYRLDMTRMACVDIN 1509
YE E C +D C +G C F CR C G+ D C+DIN
Sbjct: 252 YELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGN-CIDIN 310
Query: 1510 ECDEAEAASPLCVNARCLNTDGSFRC 1535
EC A P + C+NT+GS+ C
Sbjct: 311 ECLSISAPCP--IGHTCINTEGSYTC 334
Score = 41.6 bits (96), Expect = 0.006
Identities = 28/76 (36%), Positives = 40/76 (52%), Gaps = 11/76 (14%)
Query: 254 VHDCQ-----LCSERLGNSERVSAPDGPCPTGFE-RVNG-SCEDVDECATGGRCQHGECA 306
V++CQ LC + N+ + + C GF V+G SCED++EC++ Q ECA
Sbjct: 400 VNECQRYPGRLCGHKCENT--LGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQ--ECA 455
Query: 307 NTRGGYTCVCPDGFLL 322
N G Y C C G+ L
Sbjct: 456 NVYGSYQCYCRRGYQL 471
Score = 41.2 bits (95), Expect = 0.008
Identities = 32/131 (24%), Positives = 54/131 (41%), Gaps = 16/131 (12%)
Query: 1140 CCTVG---EGWGSGCRIQQCPGTETAE-YQSLCPHGR--GYLAPSG----DLSLRRDVDE 1189
CC +G + G C G + + +++ C + G L G D + + ++
Sbjct: 112 CCLLGRAAQAQGQSCEYSLMVGYQCGQVFRACCVKSQETGDLDVGGLQETDKIIEVEEEQ 171
Query: 1190 CQLFRDQVCKSG-----VCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACE-GG 1243
+ + C+ G C +T C C GY + + C D +EC +C G
Sbjct: 172 EDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGE 231
Query: 1244 RCVNTVGSYHC 1254
C+NTVGS+ C
Sbjct: 232 SCINTVGSFRC 242
Score = 38.9 bits (89), Expect = 0.039
Identities = 35/123 (28%), Positives = 56/123 (45%), Gaps = 17/123 (13%)
Query: 206 SAPREDGYSDASGFGYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLG 265
S+P ++ G C+ R G S + G+ +++ L G H C +
Sbjct: 447 SSPCSQECANVYGSYQCY--CRRGYQLSDVDGVTCEDI--DECALPTGGHICSYRCINIP 502
Query: 266 NSERVSAPDGPCPTGFERV--NG-SCEDVDECATG-GRCQHGE-CANTRGGYTCV---CP 317
S + S CP+ R+ NG +C+D+DEC TG C E C N +GG+ C+ CP
Sbjct: 503 GSFQCS-----CPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECP 557
Query: 318 DGF 320
+ +
Sbjct: 558 ENY 560
Score = 37.0 bits (84), Expect = 0.15
Identities = 23/59 (38%), Positives = 31/59 (52%), Gaps = 8/59 (13%)
Query: 277 CPTGFERVNG--SCEDVDECATGGR-CQHGE-CANTRGGYTC----VCPDGFLLDSSRS 327
C G++ ++ SCEDV+EC TG C+ GE C NT G + C C G+ L S
Sbjct: 201 CFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNS 259
>gi|34734068 fibulin 1 isoform A precursor [Homo sapiens]
Length = 566
Score = 239 bits (611), Expect = 1e-62
Identities = 153/398 (38%), Positives = 205/398 (51%), Gaps = 41/398 (10%)
Query: 687 DECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDEC--ENHLACPGQECVN 744
D C R PC +C +T C C +G+Q + G CEDV+EC +H G+ C+N
Sbjct: 178 DRC-RGGGPCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCIN 235
Query: 745 SPGSFQCR---TCPSGHHLHRGR-CTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYR 800
+ GSF+C+ +C +G+ L C D+DEC SG C P C NT GSFRC P +
Sbjct: 236 TVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCR--PKLQ 293
Query: 801 APSG----RPGPCADVNECLEGDFCFPHGE-CLNTDGSFAC-----TCAPGYRPGPRGAS 850
SG G C D+NECL P G C+NT+GS+ C C GY G
Sbjct: 294 CKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTR 353
Query: 851 CLDVDECSEE-DLCQSGI-CTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGS 908
C+DVDEC+ + C G C N+ GSF C C G+ C+DV+EC+ LCG
Sbjct: 354 CVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCG- 412
Query: 909 QRCENSPGSYRCVRDCDPGYHAGPEG-TCDDVDECQEYGPEICGAQRCENTPGSYRCTPA 967
+CEN+ GSY C C G+ +G +C+D++EC C +Q C N GSY+C
Sbjct: 413 HKCENTLGSYLC--SCSVGFRLSVDGRSCEDINECSS---SPC-SQECANVYGSYQCY-- 464
Query: 968 CDPGYQPTPGGG--CQDVDECRNRSFCGAHAV---CQNLPGSFQCLC-DQGYEGARDGRH 1021
C GYQ + G C+D+DEC + G H C N+PGSFQC C GY A +GR+
Sbjct: 465 CRRGYQLSDVDGVTCEDIDECALPT--GGHICSYRCINIPGSFQCSCPSSGYRLAPNGRN 522
Query: 1022 CVDVNECETLQGVCGA-ALCENVEGSFLCVCPNSPEEF 1058
C D++EC T C C N++G F C+ PE +
Sbjct: 523 CQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENY 560
Score = 217 bits (553), Expect = 6e-56
Identities = 148/389 (38%), Positives = 193/389 (49%), Gaps = 41/389 (10%)
Query: 653 PCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGR-CENTEGSFQCV 711
PC +C +T C+C G++ G C+DV+EC C G C NT GSF+C
Sbjct: 185 PCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQ 243
Query: 712 ----CPMGFQPNTAGSECEDVDECEN--HLACPGQECVNSPGSFQCRT---CPSGHHLHR 762
C G++ T + C+D+DECE+ H P C N+ GSF+CR C SG
Sbjct: 244 RDSSCGTGYEL-TEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDA 302
Query: 763 -GRCTDVDECSSGAPPCGPHGH-CTNTEGSFRC-----SCAPGYRAPSGRPGPCADVNEC 815
G C D++EC S + PC P GH C NTEGS+ C +C GY + C DV+EC
Sbjct: 303 LGNCIDINECLSISAPC-PIGHTCINTEGSYTCQKNVPNCGRGYHL-NEEGTRCVDVDEC 360
Query: 816 LE-GDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEED--LCQSGICTNTD 872
+ C C+N+ GSF C C GY C+DV+EC LC C NT
Sbjct: 361 APPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHK-CENTL 419
Query: 873 GSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGP 932
GS+ C C G R D SC D++EC + C SQ C N GSY+C C GY
Sbjct: 420 GSYLCSCSVGFRLSVDGRSCEDINECSS---SPC-SQECANVYGSYQCY--CRRGYQLSD 473
Query: 933 EG--TCDDVDECQ-EYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGG-GCQDVDECRN 988
TC+D+DEC G IC + RC N PGS++C+ GY+ P G CQD+DEC
Sbjct: 474 VDGVTCEDIDECALPTGGHIC-SYRCINIPGSFQCS-CPSSGYRLAPNGRNCQDIDECVT 531
Query: 989 RSF-CGAHAVCQNLPGSFQCL---CDQGY 1013
C + C N+ G F+CL C + Y
Sbjct: 532 GIHNCSINETCFNIQGGFRCLAFECPENY 560
Score = 215 bits (547), Expect = 3e-55
Identities = 145/386 (37%), Positives = 193/386 (50%), Gaps = 39/386 (10%)
Query: 606 DECTQSPGLCGRGACKNLPGSFRCVCPAGFR----GSACEEDVDECAQEPPPCGPGR-CD 660
D C + G C + C++ C C G++ G +CE DV+EC C G C
Sbjct: 178 DRC-RGGGPC-KQQCRDTGDEVVCSCFVGYQLLSDGVSCE-DVNECITGSHSCRLGESCI 234
Query: 661 NTAGSFHC----ACPAGFRSRGPGAPCQDVDECARSPPPCTYGR-CENTEGSFQC----V 711
NT GSF C +C G+ + C+D+DEC C C+NT GSF+C
Sbjct: 235 NTVGSFRCQRDSSCGTGYELTEDNS-CKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQ 293
Query: 712 CPMGFQPNTAGSECEDVDECENHLA-CP-GQECVNSPGSFQCR----TCPSGHHLHRG-- 763
C GF + G+ C D++EC + A CP G C+N+ GS+ C+ C G+HL+
Sbjct: 294 CKSGFIQDALGN-CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGT 352
Query: 764 RCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFP 823
RC DVDEC+ A PCG C N+ GSFRC C GY G C DVNEC
Sbjct: 353 RCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYF-DGISRMCVDVNECQRYPGRLC 411
Query: 824 HGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGH 883
+C NT GS+ C+C+ G+R G SC D++ECS Q C N GS++C C G+
Sbjct: 412 GHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQE--CANVYGSYQCYCRRGY 469
Query: 884 R-AGPDLASCLDVDECR-ERGPALCGSQRCENSPGSYRCVRDC-DPGYHAGPEG-TCDDV 939
+ + D +C D+DEC G +C S RC N PGS++C C GY P G C D+
Sbjct: 470 QLSDVDGVTCEDIDECALPTGGHIC-SYRCINIPGSFQC--SCPSSGYRLAPNGRNCQDI 526
Query: 940 DECQEYGPEICGA-QRCENTPGSYRC 964
DEC G C + C N G +RC
Sbjct: 527 DECVT-GIHNCSINETCFNIQGGFRC 551
Score = 212 bits (539), Expect = 3e-54
Identities = 150/390 (38%), Positives = 189/390 (48%), Gaps = 48/390 (12%)
Query: 490 GPGRCISRPSG--YTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGR-CENSPGSFRCV 546
GP + R +G C+C G++L G C DV+EC C G C N+ GSFRC
Sbjct: 184 GPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQ 243
Query: 547 ----CGPGFRAGPRAAECLDVDECHRVPPPC--DLGRCENTPGSFLC----VCPAGYQAA 596
CG G+ C D+DEC C D C+NT GSF C C +G+
Sbjct: 244 RDSSCGTGYEL-TEDNSCKDIDECESGIHNCLPDF-ICQNTLGSFRCRPKLQCKSGFIQD 301
Query: 597 PHGASCQDVDECTQSPGLCGRG-ACKNLPGSFRCV-----CPAGFR----GSACEEDVDE 646
G +C D++EC C G C N GS+ C C G+ G+ C DVDE
Sbjct: 302 ALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCV-DVDE 359
Query: 647 CAQEPPPCGPG-RCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTE 705
CA PCG G RC N+ GSF C C G+ G C DV+EC R P +CENT
Sbjct: 360 CAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTL 419
Query: 706 GSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHL---HR 762
GS+ C C +GF+ + G CED++EC + QEC N GS+QC C G+ L
Sbjct: 420 GSYLCSCSVGFRLSVDGRSCEDINECSSSPC--SQECANVYGSYQC-YCRRGYQLSDVDG 476
Query: 763 GRCTDVDECSSGAPPCGPH---GHCTNTEGSFRCSC-APGYR-APSGRPGPCADVNECLE 817
C D+DEC A P G H C N GSF+CSC + GYR AP+GR C D++EC+
Sbjct: 477 VTCEDIDEC---ALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGR--NCQDIDECVT 531
Query: 818 G-DFCFPHGECLNTDGSFAC---TCAPGYR 843
G C + C N G F C C YR
Sbjct: 532 GIHNCSINETCFNIQGGFRCLAFECPENYR 561
Score = 195 bits (496), Expect = 3e-49
Identities = 133/360 (36%), Positives = 176/360 (48%), Gaps = 37/360 (10%)
Query: 729 DECENHLACPGQECVNSPGSFQCRTCPSGHHLHRG--RCTDVDECSSGAPPCGPHGHCTN 786
D C C Q+C ++ C +C G+ L C DV+EC +G+ C C N
Sbjct: 178 DRCRGGGPCK-QQCRDTGDEVVC-SCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCIN 235
Query: 787 TEGSFRC----SCAPGYRAPSGRPGPCADVNECLEGDF-CFPHGECLNTDGSFACT---- 837
T GSFRC SC GY C D++EC G C P C NT GSF C
Sbjct: 236 TVGSFRCQRDSSCGTGYELTEDNS--CKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQ 293
Query: 838 CAPGYRPGPRGASCLDVDEC-SEEDLCQSG-ICTNTDGSFECI-----CPPGHRAGPDLA 890
C G+ G +C+D++EC S C G C NT+GS+ C C G+ +
Sbjct: 294 CKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGT 352
Query: 891 SCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHA-GPEGTCDDVDECQEYGPEI 949
C+DVDEC RC NSPGS+RC +C GY+ G C DV+ECQ Y +
Sbjct: 353 RCVDVDECAPPAEPCGKGHRCVNSPGSFRC--ECKTGYYFDGISRMCVDVNECQRYPGRL 410
Query: 950 CGAQRCENTPGSYRCTPACDPGYQ-PTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCL 1008
CG +CENT GSY C+ C G++ G C+D++EC + S C C N+ GS+QC
Sbjct: 411 CG-HKCENTLGSYLCS--CSVGFRLSVDGRSCEDINECSS-SPCSQE--CANVYGSYQCY 464
Query: 1009 CDQGYE-GARDGRHCVDVNECETLQG--VCGAALCENVEGSFLCVCPNSPEEFDPMTGRC 1065
C +GY+ DG C D++EC G +C + C N+ GSF C CP+S P C
Sbjct: 465 CRRGYQLSDVDGVTCEDIDECALPTGGHIC-SYRCINIPGSFQCSCPSSGYRLAPNGRNC 523
Score = 187 bits (474), Expect = 9e-47
Identities = 102/248 (41%), Positives = 138/248 (55%), Gaps = 27/248 (10%)
Query: 494 CISRPSGYTCA-----CDSGFRLSPQGTRCIDVDECRRVPPPCAPG-RCENSPGSFRCVC 547
CI+ YTC C G+ L+ +GTRC+DVDEC PC G RC NSPGSFRC C
Sbjct: 325 CINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCEC 384
Query: 548 GPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDE 607
G+ + C+DV+EC R P +CENT GS+LC C G++ + G SC+D++E
Sbjct: 385 KTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINE 444
Query: 608 CTQSPGLCGRGACKNLPGSFRCVCPAGFR-----GSACEEDVDECAQEPPPCG----PGR 658
C+ SP C + C N+ GS++C C G++ G C ED+DECA P G R
Sbjct: 445 CSSSP--CSQ-ECANVYGSYQCYCRRGYQLSDVDGVTC-EDIDECAL---PTGGHICSYR 497
Query: 659 CDNTAGSFHCACP-AGFRSRGPGAPCQDVDECARSPPPCTYGR-CENTEGSFQCV---CP 713
C N GSF C+CP +G+R G CQD+DEC C+ C N +G F+C+ CP
Sbjct: 498 CINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECP 557
Query: 714 MGFQPNTA 721
++ + A
Sbjct: 558 ENYRRSAA 565
Score = 116 bits (290), Expect = 2e-25
Identities = 68/167 (40%), Positives = 92/167 (55%), Gaps = 14/167 (8%)
Query: 482 CQRNP-QVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSP 540
CQR P ++CG +C + Y C+C GFRLS G C D++EC PC+ C N
Sbjct: 403 CQRYPGRLCGH-KCENTLGSYLCSCSVGFRLSVDGRSCEDINECS--SSPCSQ-ECANVY 458
Query: 541 GSFRCVCGPGFR-AGPRAAECLDVDECHRVPPPCDL--GRCENTPGSFLCVCP-AGYQAA 596
GS++C C G++ + C D+DEC +P + RC N PGSF C CP +GY+ A
Sbjct: 459 GSYQCYCRRGYQLSDVDGVTCEDIDEC-ALPTGGHICSYRCINIPGSFQCSCPSSGYRLA 517
Query: 597 PHGASCQDVDECTQSPGLCG-RGACKNLPGSFRCV---CPAGFRGSA 639
P+G +CQD+DEC C C N+ G FRC+ CP +R SA
Sbjct: 518 PNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSA 564
Score = 112 bits (279), Expect = 4e-24
Identities = 114/384 (29%), Positives = 146/384 (38%), Gaps = 75/384 (19%)
Query: 896 DECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEG-TCDDVDECQEYGPEICGAQR 954
D CR GP Q+C ++ C C GY +G +C+DV+EC +
Sbjct: 178 DRCRGGGPC---KQQCRDTGDEVVC--SCFVGYQLLSDGVSCEDVNECITGSHSCRLGES 232
Query: 955 CENTPGSYRCT--PACDPGYQPTPGGGCQDVDECRNRSF-CGAHAVCQNLPGSFQCL--- 1008
C NT GS+RC +C GY+ T C+D+DEC + C +CQN GSF+C
Sbjct: 233 CINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKL 292
Query: 1009 -CDQGYEGARDGRHCVDVNECETLQGVCGAA-LCENVEGSFLCV--CPNSPEEF--DPMT 1062
C G+ G +C+D+NEC ++ C C N EGS+ C PN + +
Sbjct: 293 QCKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEG 351
Query: 1063 GRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRREC----YF 1118
RCV A PP P GS R EC YF
Sbjct: 352 TRCVDVDECA---------------------PPAEPCGKGHRCVNSPGSFRCECKTGYYF 390
Query: 1119 DTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPS 1178
D I V EC G G C E LC G+ S
Sbjct: 391 D--------GISRMCVDVNECQRYPGRLCGHKC--------ENTLGSYLCSCSVGFRL-S 433
Query: 1179 GDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYY-HTQRLECIDNDECADEE 1237
D D++EC C S C N Y CYC GY + C D DECA
Sbjct: 434 VDGRSCEDINECS---SSPC-SQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECA--- 486
Query: 1238 PACEGG-----RCVNTVGSYHCTC 1256
GG RC+N GS+ C+C
Sbjct: 487 -LPTGGHICSYRCINIPGSFQCSC 509
Score = 70.9 bits (172), Expect = 9e-12
Identities = 48/146 (32%), Positives = 63/146 (43%), Gaps = 22/146 (15%)
Query: 1186 DVDECQLFRDQVCKSG-VCVNTAPGYSCY-----CSNGYYYHTQRLECIDNDECADE-EP 1238
D++EC L C G C+NT Y+C C GY+ + + C+D DECA EP
Sbjct: 308 DINEC-LSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEP 366
Query: 1239 ACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVS-NESQSLDDNLGVCWQEVGADLVCSHP 1297
+G RCVN+ GS+ C C+ DG R CV NE Q L C H
Sbjct: 367 CGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRL------------CGHK 414
Query: 1298 RLDRQATYTECCCLYGEAWGMDCALC 1323
+ +Y C C G +D C
Sbjct: 415 CENTLGSYL-CSCSVGFRLSVDGRSC 439
Score = 61.2 bits (147), Expect = 7e-09
Identities = 36/100 (36%), Positives = 46/100 (46%), Gaps = 3/100 (3%)
Query: 1171 GRGY-LAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECID 1229
GRGY L G + DVDEC + K CVN+ + C C GYY+ C+D
Sbjct: 342 GRGYHLNEEGTRCV--DVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVD 399
Query: 1230 NDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRC 1269
+EC G +C NT+GSY C+C L R C
Sbjct: 400 VNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSC 439
Score = 54.3 bits (129), Expect = 9e-07
Identities = 31/75 (41%), Positives = 34/75 (45%), Gaps = 8/75 (10%)
Query: 1467 AEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARC 1526
AE CG RCV P F C C GY D CVD+NEC LC +C
Sbjct: 364 AEPCG-----KGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGR--LC-GHKC 415
Query: 1527 LNTDGSFRCICRPGF 1541
NT GS+ C C GF
Sbjct: 416 ENTLGSYLCSCSVGF 430
Score = 52.4 bits (124), Expect = 3e-06
Identities = 30/84 (35%), Positives = 42/84 (50%), Gaps = 9/84 (10%)
Query: 1465 LEAEEC-GILDGCTNGR-CVRVPEGFTCR-----CFDGYRLDMTRMACVDINECDEAEAA 1517
++ EC I C G C+ +TC+ C GY L+ CVD++EC A A
Sbjct: 307 IDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDEC--APPA 364
Query: 1518 SPLCVNARCLNTDGSFRCICRPGF 1541
P RC+N+ GSFRC C+ G+
Sbjct: 365 EPCGKGHRCVNSPGSFRCECKTGY 388
Score = 47.8 bits (112), Expect = 8e-05
Identities = 26/78 (33%), Positives = 39/78 (50%), Gaps = 7/78 (8%)
Query: 1465 LEAEECGILDGCTNG-RCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 1523
++ EC G G +C + C C G+RL + +C DINEC ++SP +
Sbjct: 398 VDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINEC----SSSP--CS 451
Query: 1524 ARCLNTDGSFRCICRPGF 1541
C N GS++C CR G+
Sbjct: 452 QECANVYGSYQCYCRRGY 469
Score = 47.8 bits (112), Expect = 8e-05
Identities = 31/96 (32%), Positives = 41/96 (42%), Gaps = 13/96 (13%)
Query: 1452 GSYAGSLAEPYE--ELEAEECGILDGC---TNG-----RCVRVPEGFTCRC-FDGYRLDM 1500
GSY Y+ +++ C +D C T G RC+ +P F C C GYRL
Sbjct: 459 GSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAP 518
Query: 1501 TRMACVDINECDEAEAASPLCVNARCLNTDGSFRCI 1536
C DI+EC +N C N G FRC+
Sbjct: 519 NGRNCQDIDEC--VTGIHNCSINETCFNIQGGFRCL 552
Score = 46.2 bits (108), Expect = 2e-04
Identities = 27/77 (35%), Positives = 37/77 (48%), Gaps = 7/77 (9%)
Query: 1464 ELEAEECGILDGCTNG-----RCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAAS 1518
E E E+ + D C G +C + C CF GY+L ++C D+NEC +
Sbjct: 168 EEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSC 227
Query: 1519 PLCVNARCLNTDGSFRC 1535
L C+NT GSFRC
Sbjct: 228 RL--GESCINTVGSFRC 242
Score = 45.4 bits (106), Expect = 4e-04
Identities = 33/97 (34%), Positives = 45/97 (46%), Gaps = 11/97 (11%)
Query: 254 VHDCQLCSERLGNSER-VSAPDG---PCPTG--FERVNGSCEDVDECAT--GGRCQHGEC 305
V +C +E G R V++P C TG F+ ++ C DV+EC G C H +C
Sbjct: 357 VDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH-KC 415
Query: 306 ANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPC 342
NT G Y C C GF L SC + + + PC
Sbjct: 416 ENTLGSYLCSCSVGFRLSVDGRSC--EDINECSSSPC 450
Score = 45.4 bits (106), Expect = 4e-04
Identities = 28/92 (30%), Positives = 45/92 (48%), Gaps = 8/92 (8%)
Query: 1452 GSYAGSLAEPYE-ELEAEECGILDGCTNG----RCVRVPEGFTCRCFDGYRL-DMTRMAC 1505
GSY S + + ++ C ++ C++ C V + C C GY+L D+ + C
Sbjct: 420 GSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTC 479
Query: 1506 VDINECDEAEAASPLCVNARCLNTDGSFRCIC 1537
DI+EC +C + RC+N GSF+C C
Sbjct: 480 EDIDEC-ALPTGGHIC-SYRCINIPGSFQCSC 509
Score = 44.7 bits (104), Expect = 7e-04
Identities = 30/101 (29%), Positives = 45/101 (44%), Gaps = 13/101 (12%)
Query: 253 GVHDCQ---LCSERLGNSERVSAPDGPCPTGF-ERVNGSCEDVDECAT-GGRCQHGE-CA 306
G+H+C +C LG+ P C +GF + G+C D++EC + C G C
Sbjct: 269 GIHNCLPDFICQNTLGSFR--CRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCI 326
Query: 307 NTRGGYTCV-----CPDGFLLDSSRSSCISQHVISEAKGPC 342
NT G YTC C G+ L+ + C+ + PC
Sbjct: 327 NTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPC 367
Score = 43.5 bits (101), Expect = 0.002
Identities = 31/100 (31%), Positives = 44/100 (44%), Gaps = 13/100 (13%)
Query: 253 GVHDCQL---CSERLGNSERVSAPDGPCPTGFERV-NGSCEDVDECATG--GRCQHGECA 306
G H C+L C +G+ D C TG+E + SC+D+DEC +G C
Sbjct: 223 GSHSCRLGESCINTVGSFR--CQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQ 280
Query: 307 NTRGGYTC----VCPDGFLLDSSRSSCISQHVISEAKGPC 342
NT G + C C GF+ D + +CI + PC
Sbjct: 281 NTLGSFRCRPKLQCKSGFIQD-ALGNCIDINECLSISAPC 319
Score = 41.6 bits (96), Expect = 0.006
Identities = 28/86 (32%), Positives = 36/86 (41%), Gaps = 15/86 (17%)
Query: 1462 YEELEAEECGILDGCTNGR--------CVRVPEGFTCR----CFDGYRLDMTRMACVDIN 1509
YE E C +D C +G C F CR C G+ D C+DIN
Sbjct: 252 YELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGN-CIDIN 310
Query: 1510 ECDEAEAASPLCVNARCLNTDGSFRC 1535
EC A P + C+NT+GS+ C
Sbjct: 311 ECLSISAPCP--IGHTCINTEGSYTC 334
Score = 41.6 bits (96), Expect = 0.006
Identities = 28/76 (36%), Positives = 40/76 (52%), Gaps = 11/76 (14%)
Query: 254 VHDCQ-----LCSERLGNSERVSAPDGPCPTGFE-RVNG-SCEDVDECATGGRCQHGECA 306
V++CQ LC + N+ + + C GF V+G SCED++EC++ Q ECA
Sbjct: 400 VNECQRYPGRLCGHKCENT--LGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQ--ECA 455
Query: 307 NTRGGYTCVCPDGFLL 322
N G Y C C G+ L
Sbjct: 456 NVYGSYQCYCRRGYQL 471
Score = 41.2 bits (95), Expect = 0.008
Identities = 32/131 (24%), Positives = 54/131 (41%), Gaps = 16/131 (12%)
Query: 1140 CCTVG---EGWGSGCRIQQCPGTETAE-YQSLCPHGR--GYLAPSG----DLSLRRDVDE 1189
CC +G + G C G + + +++ C + G L G D + + ++
Sbjct: 112 CCLLGRAAQAQGQSCEYSLMVGYQCGQVFRACCVKSQETGDLDVGGLQETDKIIEVEEEQ 171
Query: 1190 CQLFRDQVCKSG-----VCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACE-GG 1243
+ + C+ G C +T C C GY + + C D +EC +C G
Sbjct: 172 EDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGE 231
Query: 1244 RCVNTVGSYHC 1254
C+NTVGS+ C
Sbjct: 232 SCINTVGSFRC 242
Score = 38.9 bits (89), Expect = 0.039
Identities = 35/123 (28%), Positives = 56/123 (45%), Gaps = 17/123 (13%)
Query: 206 SAPREDGYSDASGFGYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLG 265
S+P ++ G C+ R G S + G+ +++ L G H C +
Sbjct: 447 SSPCSQECANVYGSYQCY--CRRGYQLSDVDGVTCEDI--DECALPTGGHICSYRCINIP 502
Query: 266 NSERVSAPDGPCPTGFERV--NG-SCEDVDECATG-GRCQHGE-CANTRGGYTCV---CP 317
S + S CP+ R+ NG +C+D+DEC TG C E C N +GG+ C+ CP
Sbjct: 503 GSFQCS-----CPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECP 557
Query: 318 DGF 320
+ +
Sbjct: 558 ENY 560
Score = 37.0 bits (84), Expect = 0.15
Identities = 23/59 (38%), Positives = 31/59 (52%), Gaps = 8/59 (13%)
Query: 277 CPTGFERVNG--SCEDVDECATGGR-CQHGE-CANTRGGYTC----VCPDGFLLDSSRS 327
C G++ ++ SCEDV+EC TG C+ GE C NT G + C C G+ L S
Sbjct: 201 CFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNS 259
>gi|34734066 fibulin 1 isoform D [Homo sapiens]
Length = 703
Score = 239 bits (611), Expect = 1e-62
Identities = 153/398 (38%), Positives = 205/398 (51%), Gaps = 41/398 (10%)
Query: 687 DECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDEC--ENHLACPGQECVN 744
D C R PC +C +T C C +G+Q + G CEDV+EC +H G+ C+N
Sbjct: 178 DRC-RGGGPCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCIN 235
Query: 745 SPGSFQCR---TCPSGHHLHRGR-CTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYR 800
+ GSF+C+ +C +G+ L C D+DEC SG C P C NT GSFRC P +
Sbjct: 236 TVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCR--PKLQ 293
Query: 801 APSG----RPGPCADVNECLEGDFCFPHGE-CLNTDGSFAC-----TCAPGYRPGPRGAS 850
SG G C D+NECL P G C+NT+GS+ C C GY G
Sbjct: 294 CKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTR 353
Query: 851 CLDVDECSEE-DLCQSGI-CTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGS 908
C+DVDEC+ + C G C N+ GSF C C G+ C+DV+EC+ LCG
Sbjct: 354 CVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCG- 412
Query: 909 QRCENSPGSYRCVRDCDPGYHAGPEG-TCDDVDECQEYGPEICGAQRCENTPGSYRCTPA 967
+CEN+ GSY C C G+ +G +C+D++EC C +Q C N GSY+C
Sbjct: 413 HKCENTLGSYLC--SCSVGFRLSVDGRSCEDINECSS---SPC-SQECANVYGSYQCY-- 464
Query: 968 CDPGYQPTPGGG--CQDVDECRNRSFCGAHAV---CQNLPGSFQCLC-DQGYEGARDGRH 1021
C GYQ + G C+D+DEC + G H C N+PGSFQC C GY A +GR+
Sbjct: 465 CRRGYQLSDVDGVTCEDIDECALPT--GGHICSYRCINIPGSFQCSCPSSGYRLAPNGRN 522
Query: 1022 CVDVNECETLQGVCGA-ALCENVEGSFLCVCPNSPEEF 1058
C D++EC T C C N++G F C+ PE +
Sbjct: 523 CQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENY 560
Score = 217 bits (553), Expect = 6e-56
Identities = 148/389 (38%), Positives = 193/389 (49%), Gaps = 41/389 (10%)
Query: 653 PCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGR-CENTEGSFQCV 711
PC +C +T C+C G++ G C+DV+EC C G C NT GSF+C
Sbjct: 185 PCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQ 243
Query: 712 ----CPMGFQPNTAGSECEDVDECEN--HLACPGQECVNSPGSFQCRT---CPSGHHLHR 762
C G++ T + C+D+DECE+ H P C N+ GSF+CR C SG
Sbjct: 244 RDSSCGTGYEL-TEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDA 302
Query: 763 -GRCTDVDECSSGAPPCGPHGH-CTNTEGSFRC-----SCAPGYRAPSGRPGPCADVNEC 815
G C D++EC S + PC P GH C NTEGS+ C +C GY + C DV+EC
Sbjct: 303 LGNCIDINECLSISAPC-PIGHTCINTEGSYTCQKNVPNCGRGYHL-NEEGTRCVDVDEC 360
Query: 816 LE-GDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEED--LCQSGICTNTD 872
+ C C+N+ GSF C C GY C+DV+EC LC C NT
Sbjct: 361 APPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHK-CENTL 419
Query: 873 GSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGP 932
GS+ C C G R D SC D++EC + C SQ C N GSY+C C GY
Sbjct: 420 GSYLCSCSVGFRLSVDGRSCEDINECSS---SPC-SQECANVYGSYQCY--CRRGYQLSD 473
Query: 933 EG--TCDDVDECQ-EYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGG-GCQDVDECRN 988
TC+D+DEC G IC + RC N PGS++C+ GY+ P G CQD+DEC
Sbjct: 474 VDGVTCEDIDECALPTGGHIC-SYRCINIPGSFQCS-CPSSGYRLAPNGRNCQDIDECVT 531
Query: 989 RSF-CGAHAVCQNLPGSFQCL---CDQGY 1013
C + C N+ G F+CL C + Y
Sbjct: 532 GIHNCSINETCFNIQGGFRCLAFECPENY 560
Score = 215 bits (547), Expect = 3e-55
Identities = 145/386 (37%), Positives = 193/386 (50%), Gaps = 39/386 (10%)
Query: 606 DECTQSPGLCGRGACKNLPGSFRCVCPAGFR----GSACEEDVDECAQEPPPCGPGR-CD 660
D C + G C + C++ C C G++ G +CE DV+EC C G C
Sbjct: 178 DRC-RGGGPC-KQQCRDTGDEVVCSCFVGYQLLSDGVSCE-DVNECITGSHSCRLGESCI 234
Query: 661 NTAGSFHC----ACPAGFRSRGPGAPCQDVDECARSPPPCTYGR-CENTEGSFQC----V 711
NT GSF C +C G+ + C+D+DEC C C+NT GSF+C
Sbjct: 235 NTVGSFRCQRDSSCGTGYELTEDNS-CKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQ 293
Query: 712 CPMGFQPNTAGSECEDVDECENHLA-CP-GQECVNSPGSFQCR----TCPSGHHLHRG-- 763
C GF + G+ C D++EC + A CP G C+N+ GS+ C+ C G+HL+
Sbjct: 294 CKSGFIQDALGN-CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGT 352
Query: 764 RCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFP 823
RC DVDEC+ A PCG C N+ GSFRC C GY G C DVNEC
Sbjct: 353 RCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYF-DGISRMCVDVNECQRYPGRLC 411
Query: 824 HGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGH 883
+C NT GS+ C+C+ G+R G SC D++ECS Q C N GS++C C G+
Sbjct: 412 GHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQE--CANVYGSYQCYCRRGY 469
Query: 884 R-AGPDLASCLDVDECR-ERGPALCGSQRCENSPGSYRCVRDC-DPGYHAGPEG-TCDDV 939
+ + D +C D+DEC G +C S RC N PGS++C C GY P G C D+
Sbjct: 470 QLSDVDGVTCEDIDECALPTGGHIC-SYRCINIPGSFQC--SCPSSGYRLAPNGRNCQDI 526
Query: 940 DECQEYGPEICGA-QRCENTPGSYRC 964
DEC G C + C N G +RC
Sbjct: 527 DECVT-GIHNCSINETCFNIQGGFRC 551
Score = 212 bits (540), Expect = 2e-54
Identities = 149/396 (37%), Positives = 192/396 (48%), Gaps = 44/396 (11%)
Query: 564 DECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRG-ACKN 622
D C R PC +C +T +C C GYQ G SC+DV+EC C G +C N
Sbjct: 178 DRC-RGGGPCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCIN 235
Query: 623 LPGSFRC----VCPAGF---RGSACEEDVDECAQEPPPCGPG-RCDNTAGSFHC----AC 670
GSFRC C G+ ++C +D+DEC C P C NT GSF C C
Sbjct: 236 TVGSFRCQRDSSCGTGYELTEDNSC-KDIDECESGIHNCLPDFICQNTLGSFRCRPKLQC 294
Query: 671 PAGFRSRGPGAPCQDVDECARSPPPCTYGR-CENTEGSFQCV-----CPMGFQPNTAGSE 724
+GF G C D++EC PC G C NTEGS+ C C G+ N G+
Sbjct: 295 KSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTR 353
Query: 725 CEDVDEC--ENHLACPGQECVNSPGSFQCRTCPSGHHLH--RGRCTDVDECSSGAPPCGP 780
C DVDEC G CVNSPGSF+C C +G++ C DV+EC P
Sbjct: 354 CVDVDECAPPAEPCGKGHRCVNSPGSFRCE-CKTGYYFDGISRMCVDVNECQ--RYPGRL 410
Query: 781 HGH-CTNTEGSFRCSCAPGYR-APSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTC 838
GH C NT GS+ CSC+ G+R + GR C D+NEC EC N GS+ C C
Sbjct: 411 CGHKCENTLGSYLCSCSVGFRLSVDGR--SCEDINECSSSPC---SQECANVYGSYQCYC 465
Query: 839 APGYR-PGPRGASCLDVDEC---SEEDLCQSGICTNTDGSFECICP-PGHRAGPDLASCL 893
GY+ G +C D+DEC + +C S C N GSF+C CP G+R P+ +C
Sbjct: 466 RRGYQLSDVDGVTCEDIDECALPTGGHIC-SYRCINIPGSFQCSCPSSGYRLAPNGRNCQ 524
Query: 894 DVDECRERGPALCGSQRCENSPGSYRCVR-DCDPGY 928
D+DEC ++ C N G +RC+ +C Y
Sbjct: 525 DIDECVTGIHNCSINETCFNIQGGFRCLAFECPENY 560
Score = 206 bits (525), Expect = 1e-52
Identities = 134/383 (34%), Positives = 172/383 (44%), Gaps = 77/383 (20%)
Query: 490 GPGRCISRPSG--YTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGR-CENSPGSFRC- 545
GP + R +G C+C G++L G C DV+EC C G C N+ GSFRC
Sbjct: 184 GPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQ 243
Query: 546 ---VCGPG----------------------------------FRAGPR-----------A 557
CG G FR P+
Sbjct: 244 RDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDAL 303
Query: 558 AECLDVDECHRVPPPCDLGR-CENTPGSFLCV-----CPAGYQAAPHGASCQDVDECTQS 611
C+D++EC + PC +G C NT GS+ C C GY G C DVDEC
Sbjct: 304 GNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPP 363
Query: 612 PGLCGRG-ACKNLPGSFRCVCPAGFRGSACEE---DVDECAQEPPPCGPGRCDNTAGSFH 667
CG+G C N PGSFRC C G+ DV+EC + P +C+NT GS+
Sbjct: 364 AEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYL 423
Query: 668 CACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQ-PNTAGSECE 726
C+C GFR G C+D++EC+ S PC+ C N GS+QC C G+Q + G CE
Sbjct: 424 CSCSVGFRLSVDGRSCEDINECSSS--PCSQ-ECANVYGSYQCYCRRGYQLSDVDGVTCE 480
Query: 727 DVDECE----NHLACPGQECVNSPGSFQCRTCPSGHHL-HRGR-CTDVDECSSGAPPCGP 780
D+DEC H+ C+N PGSFQC SG+ L GR C D+DEC +G C
Sbjct: 481 DIDECALPTGGHIC--SYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSI 538
Query: 781 HGHCTNTEGSFRC---SCAPGYR 800
+ C N +G FRC C YR
Sbjct: 539 NETCFNIQGGFRCLAFECPENYR 561
Score = 195 bits (496), Expect = 3e-49
Identities = 133/360 (36%), Positives = 176/360 (48%), Gaps = 37/360 (10%)
Query: 729 DECENHLACPGQECVNSPGSFQCRTCPSGHHLHRG--RCTDVDECSSGAPPCGPHGHCTN 786
D C C Q+C ++ C +C G+ L C DV+EC +G+ C C N
Sbjct: 178 DRCRGGGPCK-QQCRDTGDEVVC-SCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCIN 235
Query: 787 TEGSFRC----SCAPGYRAPSGRPGPCADVNECLEGDF-CFPHGECLNTDGSFACT---- 837
T GSFRC SC GY C D++EC G C P C NT GSF C
Sbjct: 236 TVGSFRCQRDSSCGTGYELTEDNS--CKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQ 293
Query: 838 CAPGYRPGPRGASCLDVDEC-SEEDLCQSG-ICTNTDGSFECI-----CPPGHRAGPDLA 890
C G+ G +C+D++EC S C G C NT+GS+ C C G+ +
Sbjct: 294 CKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGT 352
Query: 891 SCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHA-GPEGTCDDVDECQEYGPEI 949
C+DVDEC RC NSPGS+RC +C GY+ G C DV+ECQ Y +
Sbjct: 353 RCVDVDECAPPAEPCGKGHRCVNSPGSFRC--ECKTGYYFDGISRMCVDVNECQRYPGRL 410
Query: 950 CGAQRCENTPGSYRCTPACDPGYQ-PTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCL 1008
CG +CENT GSY C+ C G++ G C+D++EC + S C C N+ GS+QC
Sbjct: 411 CG-HKCENTLGSYLCS--CSVGFRLSVDGRSCEDINECSS-SPCSQE--CANVYGSYQCY 464
Query: 1009 CDQGYE-GARDGRHCVDVNECETLQG--VCGAALCENVEGSFLCVCPNSPEEFDPMTGRC 1065
C +GY+ DG C D++EC G +C + C N+ GSF C CP+S P C
Sbjct: 465 CRRGYQLSDVDGVTCEDIDECALPTGGHIC-SYRCINIPGSFQCSCPSSGYRLAPNGRNC 523
Score = 189 bits (481), Expect = 1e-47
Identities = 108/275 (39%), Positives = 147/275 (53%), Gaps = 29/275 (10%)
Query: 494 CISRPSGYTCA-----CDSGFRLSPQGTRCIDVDECRRVPPPCAPG-RCENSPGSFRCVC 547
CI+ YTC C G+ L+ +GTRC+DVDEC PC G RC NSPGSFRC C
Sbjct: 325 CINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCEC 384
Query: 548 GPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDE 607
G+ + C+DV+EC R P +CENT GS+LC C G++ + G SC+D++E
Sbjct: 385 KTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINE 444
Query: 608 CTQSPGLCGRGACKNLPGSFRCVCPAGFR-----GSACEEDVDECAQEPPPCG----PGR 658
C+ SP C + C N+ GS++C C G++ G C ED+DECA P G R
Sbjct: 445 CSSSP--CSQ-ECANVYGSYQCYCRRGYQLSDVDGVTC-EDIDECAL---PTGGHICSYR 497
Query: 659 CDNTAGSFHCACP-AGFRSRGPGAPCQDVDECARSPPPCTYGR-CENTEGSFQCV---CP 713
C N GSF C+CP +G+R G CQD+DEC C+ C N +G F+C+ CP
Sbjct: 498 CINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECP 557
Query: 714 MGFQPNTAGSECEDVDECENHLACPGQE--CVNSP 746
++ + A + E D +C + CV P
Sbjct: 558 ENYRRSAATLQQEKTDTVRCIKSCRPNDVTCVFDP 592
Score = 135 bits (341), Expect = 2e-31
Identities = 76/207 (36%), Positives = 103/207 (49%), Gaps = 18/207 (8%)
Query: 482 CQRNPQVCGPG-RCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSP 540
C + CG G RC++ P + C C +G+ C+DV+EC+R P +CEN+
Sbjct: 360 CAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTL 419
Query: 541 GSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAP-HG 599
GS+ C C GFR C D++EC PC C N GS+ C C GYQ + G
Sbjct: 420 GSYLCSCSVGFRLSVDGRSCEDINECS--SSPCS-QECANVYGSYQCYCRRGYQLSDVDG 476
Query: 600 ASCQDVDECTQSPG--LCGRGACKNLPGSFRCVCP-AGFR----GSACEEDVDECAQEPP 652
+C+D+DEC G +C C N+PGSF+C CP +G+R G C +D+DEC
Sbjct: 477 VTCEDIDECALPTGGHICSY-RCINIPGSFQCSCPSSGYRLAPNGRNC-QDIDECVTGIH 534
Query: 653 PCGPGR-CDNTAGSFHC---ACPAGFR 675
C C N G F C CP +R
Sbjct: 535 NCSINETCFNIQGGFRCLAFECPENYR 561
Score = 112 bits (279), Expect = 4e-24
Identities = 114/384 (29%), Positives = 146/384 (38%), Gaps = 75/384 (19%)
Query: 896 DECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEG-TCDDVDECQEYGPEICGAQR 954
D CR GP Q+C ++ C C GY +G +C+DV+EC +
Sbjct: 178 DRCRGGGPC---KQQCRDTGDEVVC--SCFVGYQLLSDGVSCEDVNECITGSHSCRLGES 232
Query: 955 CENTPGSYRCT--PACDPGYQPTPGGGCQDVDECRNRSF-CGAHAVCQNLPGSFQCL--- 1008
C NT GS+RC +C GY+ T C+D+DEC + C +CQN GSF+C
Sbjct: 233 CINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKL 292
Query: 1009 -CDQGYEGARDGRHCVDVNECETLQGVCGAA-LCENVEGSFLCV--CPNSPEEF--DPMT 1062
C G+ G +C+D+NEC ++ C C N EGS+ C PN + +
Sbjct: 293 QCKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEG 351
Query: 1063 GRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRREC----YF 1118
RCV A PP P GS R EC YF
Sbjct: 352 TRCVDVDECA---------------------PPAEPCGKGHRCVNSPGSFRCECKTGYYF 390
Query: 1119 DTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPS 1178
D I V EC G G C E LC G+ S
Sbjct: 391 D--------GISRMCVDVNECQRYPGRLCGHKC--------ENTLGSYLCSCSVGFRL-S 433
Query: 1179 GDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYY-HTQRLECIDNDECADEE 1237
D D++EC C S C N Y CYC GY + C D DECA
Sbjct: 434 VDGRSCEDINECS---SSPC-SQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECA--- 486
Query: 1238 PACEGG-----RCVNTVGSYHCTC 1256
GG RC+N GS+ C+C
Sbjct: 487 -LPTGGHICSYRCINIPGSFQCSC 509
Score = 70.9 bits (172), Expect = 9e-12
Identities = 48/146 (32%), Positives = 63/146 (43%), Gaps = 22/146 (15%)
Query: 1186 DVDECQLFRDQVCKSG-VCVNTAPGYSCY-----CSNGYYYHTQRLECIDNDECADE-EP 1238
D++EC L C G C+NT Y+C C GY+ + + C+D DECA EP
Sbjct: 308 DINEC-LSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEP 366
Query: 1239 ACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVS-NESQSLDDNLGVCWQEVGADLVCSHP 1297
+G RCVN+ GS+ C C+ DG R CV NE Q L C H
Sbjct: 367 CGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRL------------CGHK 414
Query: 1298 RLDRQATYTECCCLYGEAWGMDCALC 1323
+ +Y C C G +D C
Sbjct: 415 CENTLGSYL-CSCSVGFRLSVDGRSC 439
Score = 61.2 bits (147), Expect = 7e-09
Identities = 36/100 (36%), Positives = 46/100 (46%), Gaps = 3/100 (3%)
Query: 1171 GRGY-LAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECID 1229
GRGY L G + DVDEC + K CVN+ + C C GYY+ C+D
Sbjct: 342 GRGYHLNEEGTRCV--DVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVD 399
Query: 1230 NDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRC 1269
+EC G +C NT+GSY C+C L R C
Sbjct: 400 VNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSC 439
Score = 54.3 bits (129), Expect = 9e-07
Identities = 31/75 (41%), Positives = 34/75 (45%), Gaps = 8/75 (10%)
Query: 1467 AEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARC 1526
AE CG RCV P F C C GY D CVD+NEC LC +C
Sbjct: 364 AEPCG-----KGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGR--LC-GHKC 415
Query: 1527 LNTDGSFRCICRPGF 1541
NT GS+ C C GF
Sbjct: 416 ENTLGSYLCSCSVGF 430
Score = 52.4 bits (124), Expect = 3e-06
Identities = 30/84 (35%), Positives = 42/84 (50%), Gaps = 9/84 (10%)
Query: 1465 LEAEEC-GILDGCTNGR-CVRVPEGFTCR-----CFDGYRLDMTRMACVDINECDEAEAA 1517
++ EC I C G C+ +TC+ C GY L+ CVD++EC A A
Sbjct: 307 IDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDEC--APPA 364
Query: 1518 SPLCVNARCLNTDGSFRCICRPGF 1541
P RC+N+ GSFRC C+ G+
Sbjct: 365 EPCGKGHRCVNSPGSFRCECKTGY 388
Score = 47.8 bits (112), Expect = 8e-05
Identities = 26/78 (33%), Positives = 39/78 (50%), Gaps = 7/78 (8%)
Query: 1465 LEAEECGILDGCTNG-RCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 1523
++ EC G G +C + C C G+RL + +C DINEC ++SP +
Sbjct: 398 VDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINEC----SSSP--CS 451
Query: 1524 ARCLNTDGSFRCICRPGF 1541
C N GS++C CR G+
Sbjct: 452 QECANVYGSYQCYCRRGY 469
Score = 47.8 bits (112), Expect = 8e-05
Identities = 31/96 (32%), Positives = 41/96 (42%), Gaps = 13/96 (13%)
Query: 1452 GSYAGSLAEPYE--ELEAEECGILDGC---TNG-----RCVRVPEGFTCRC-FDGYRLDM 1500
GSY Y+ +++ C +D C T G RC+ +P F C C GYRL
Sbjct: 459 GSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAP 518
Query: 1501 TRMACVDINECDEAEAASPLCVNARCLNTDGSFRCI 1536
C DI+EC +N C N G FRC+
Sbjct: 519 NGRNCQDIDEC--VTGIHNCSINETCFNIQGGFRCL 552
Score = 46.2 bits (108), Expect = 2e-04
Identities = 27/77 (35%), Positives = 37/77 (48%), Gaps = 7/77 (9%)
Query: 1464 ELEAEECGILDGCTNG-----RCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAAS 1518
E E E+ + D C G +C + C CF GY+L ++C D+NEC +
Sbjct: 168 EEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSC 227
Query: 1519 PLCVNARCLNTDGSFRC 1535
L C+NT GSFRC
Sbjct: 228 RL--GESCINTVGSFRC 242
Score = 45.4 bits (106), Expect = 4e-04
Identities = 33/97 (34%), Positives = 45/97 (46%), Gaps = 11/97 (11%)
Query: 254 VHDCQLCSERLGNSER-VSAPDG---PCPTG--FERVNGSCEDVDECAT--GGRCQHGEC 305
V +C +E G R V++P C TG F+ ++ C DV+EC G C H +C
Sbjct: 357 VDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH-KC 415
Query: 306 ANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPC 342
NT G Y C C GF L SC + + + PC
Sbjct: 416 ENTLGSYLCSCSVGFRLSVDGRSC--EDINECSSSPC 450
Score = 45.4 bits (106), Expect = 4e-04
Identities = 28/92 (30%), Positives = 45/92 (48%), Gaps = 8/92 (8%)
Query: 1452 GSYAGSLAEPYE-ELEAEECGILDGCTNG----RCVRVPEGFTCRCFDGYRL-DMTRMAC 1505
GSY S + + ++ C ++ C++ C V + C C GY+L D+ + C
Sbjct: 420 GSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTC 479
Query: 1506 VDINECDEAEAASPLCVNARCLNTDGSFRCIC 1537
DI+EC +C + RC+N GSF+C C
Sbjct: 480 EDIDEC-ALPTGGHIC-SYRCINIPGSFQCSC 509
Score = 44.7 bits (104), Expect = 7e-04
Identities = 30/101 (29%), Positives = 45/101 (44%), Gaps = 13/101 (12%)
Query: 253 GVHDCQ---LCSERLGNSERVSAPDGPCPTGF-ERVNGSCEDVDECAT-GGRCQHGE-CA 306
G+H+C +C LG+ P C +GF + G+C D++EC + C G C
Sbjct: 269 GIHNCLPDFICQNTLGSFR--CRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCI 326
Query: 307 NTRGGYTCV-----CPDGFLLDSSRSSCISQHVISEAKGPC 342
NT G YTC C G+ L+ + C+ + PC
Sbjct: 327 NTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPC 367
Score = 43.5 bits (101), Expect = 0.002
Identities = 31/100 (31%), Positives = 44/100 (44%), Gaps = 13/100 (13%)
Query: 253 GVHDCQL---CSERLGNSERVSAPDGPCPTGFERV-NGSCEDVDECATG--GRCQHGECA 306
G H C+L C +G+ D C TG+E + SC+D+DEC +G C
Sbjct: 223 GSHSCRLGESCINTVGSFR--CQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQ 280
Query: 307 NTRGGYTC----VCPDGFLLDSSRSSCISQHVISEAKGPC 342
NT G + C C GF+ D + +CI + PC
Sbjct: 281 NTLGSFRCRPKLQCKSGFIQD-ALGNCIDINECLSISAPC 319
Score = 41.6 bits (96), Expect = 0.006
Identities = 28/86 (32%), Positives = 36/86 (41%), Gaps = 15/86 (17%)
Query: 1462 YEELEAEECGILDGCTNGR--------CVRVPEGFTCR----CFDGYRLDMTRMACVDIN 1509
YE E C +D C +G C F CR C G+ D C+DIN
Sbjct: 252 YELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGN-CIDIN 310
Query: 1510 ECDEAEAASPLCVNARCLNTDGSFRC 1535
EC A P + C+NT+GS+ C
Sbjct: 311 ECLSISAPCP--IGHTCINTEGSYTC 334
Score = 41.6 bits (96), Expect = 0.006
Identities = 28/76 (36%), Positives = 40/76 (52%), Gaps = 11/76 (14%)
Query: 254 VHDCQ-----LCSERLGNSERVSAPDGPCPTGFE-RVNG-SCEDVDECATGGRCQHGECA 306
V++CQ LC + N+ + + C GF V+G SCED++EC++ Q ECA
Sbjct: 400 VNECQRYPGRLCGHKCENT--LGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQ--ECA 455
Query: 307 NTRGGYTCVCPDGFLL 322
N G Y C C G+ L
Sbjct: 456 NVYGSYQCYCRRGYQL 471
Score = 41.2 bits (95), Expect = 0.008
Identities = 32/131 (24%), Positives = 54/131 (41%), Gaps = 16/131 (12%)
Query: 1140 CCTVG---EGWGSGCRIQQCPGTETAE-YQSLCPHGR--GYLAPSG----DLSLRRDVDE 1189
CC +G + G C G + + +++ C + G L G D + + ++
Sbjct: 112 CCLLGRAAQAQGQSCEYSLMVGYQCGQVFRACCVKSQETGDLDVGGLQETDKIIEVEEEQ 171
Query: 1190 CQLFRDQVCKSG-----VCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACE-GG 1243
+ + C+ G C +T C C GY + + C D +EC +C G
Sbjct: 172 EDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGE 231
Query: 1244 RCVNTVGSYHC 1254
C+NTVGS+ C
Sbjct: 232 SCINTVGSFRC 242
Score = 38.9 bits (89), Expect = 0.039
Identities = 35/123 (28%), Positives = 56/123 (45%), Gaps = 17/123 (13%)
Query: 206 SAPREDGYSDASGFGYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLG 265
S+P ++ G C+ R G S + G+ +++ L G H C +
Sbjct: 447 SSPCSQECANVYGSYQCY--CRRGYQLSDVDGVTCEDI--DECALPTGGHICSYRCINIP 502
Query: 266 NSERVSAPDGPCPTGFERV--NG-SCEDVDECATG-GRCQHGE-CANTRGGYTCV---CP 317
S + S CP+ R+ NG +C+D+DEC TG C E C N +GG+ C+ CP
Sbjct: 503 GSFQCS-----CPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECP 557
Query: 318 DGF 320
+ +
Sbjct: 558 ENY 560
Score = 37.0 bits (84), Expect = 0.15
Identities = 23/59 (38%), Positives = 31/59 (52%), Gaps = 8/59 (13%)
Query: 277 CPTGFERVNG--SCEDVDECATGGR-CQHGE-CANTRGGYTC----VCPDGFLLDSSRS 327
C G++ ++ SCEDV+EC TG C+ GE C NT G + C C G+ L S
Sbjct: 201 CFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNS 259
>gi|34734062 fibulin 1 isoform C precursor [Homo sapiens]
Length = 683
Score = 239 bits (611), Expect = 1e-62
Identities = 153/398 (38%), Positives = 205/398 (51%), Gaps = 41/398 (10%)
Query: 687 DECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDEC--ENHLACPGQECVN 744
D C R PC +C +T C C +G+Q + G CEDV+EC +H G+ C+N
Sbjct: 178 DRC-RGGGPCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCIN 235
Query: 745 SPGSFQCR---TCPSGHHLHRGR-CTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYR 800
+ GSF+C+ +C +G+ L C D+DEC SG C P C NT GSFRC P +
Sbjct: 236 TVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCR--PKLQ 293
Query: 801 APSG----RPGPCADVNECLEGDFCFPHGE-CLNTDGSFAC-----TCAPGYRPGPRGAS 850
SG G C D+NECL P G C+NT+GS+ C C GY G
Sbjct: 294 CKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTR 353
Query: 851 CLDVDECSEE-DLCQSGI-CTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGS 908
C+DVDEC+ + C G C N+ GSF C C G+ C+DV+EC+ LCG
Sbjct: 354 CVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCG- 412
Query: 909 QRCENSPGSYRCVRDCDPGYHAGPEG-TCDDVDECQEYGPEICGAQRCENTPGSYRCTPA 967
+CEN+ GSY C C G+ +G +C+D++EC C +Q C N GSY+C
Sbjct: 413 HKCENTLGSYLC--SCSVGFRLSVDGRSCEDINECSS---SPC-SQECANVYGSYQCY-- 464
Query: 968 CDPGYQPTPGGG--CQDVDECRNRSFCGAHAV---CQNLPGSFQCLC-DQGYEGARDGRH 1021
C GYQ + G C+D+DEC + G H C N+PGSFQC C GY A +GR+
Sbjct: 465 CRRGYQLSDVDGVTCEDIDECALPT--GGHICSYRCINIPGSFQCSCPSSGYRLAPNGRN 522
Query: 1022 CVDVNECETLQGVCGA-ALCENVEGSFLCVCPNSPEEF 1058
C D++EC T C C N++G F C+ PE +
Sbjct: 523 CQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENY 560
Score = 219 bits (557), Expect = 2e-56
Identities = 153/425 (36%), Positives = 205/425 (48%), Gaps = 47/425 (11%)
Query: 606 DECTQSPGLCGRGACKNLPGSFRCVCPAGFR----GSACEEDVDECAQEPPPCGPGR-CD 660
D C + G C + C++ C C G++ G +CE DV+EC C G C
Sbjct: 178 DRC-RGGGPC-KQQCRDTGDEVVCSCFVGYQLLSDGVSCE-DVNECITGSHSCRLGESCI 234
Query: 661 NTAGSFHC----ACPAGFRSRGPGAPCQDVDECARSPPPCTYGR-CENTEGSFQC----V 711
NT GSF C +C G+ + C+D+DEC C C+NT GSF+C
Sbjct: 235 NTVGSFRCQRDSSCGTGYELTEDNS-CKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQ 293
Query: 712 CPMGFQPNTAGSECEDVDECENHLA-CP-GQECVNSPGSFQCR----TCPSGHHLHRG-- 763
C GF + G+ C D++EC + A CP G C+N+ GS+ C+ C G+HL+
Sbjct: 294 CKSGFIQDALGN-CIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGT 352
Query: 764 RCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFP 823
RC DVDEC+ A PCG C N+ GSFRC C GY G C DVNEC
Sbjct: 353 RCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYF-DGISRMCVDVNECQRYPGRLC 411
Query: 824 HGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGH 883
+C NT GS+ C+C+ G+R G SC D++ECS Q C N GS++C C G+
Sbjct: 412 GHKCENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQE--CANVYGSYQCYCRRGY 469
Query: 884 R-AGPDLASCLDVDECR-ERGPALCGSQRCENSPGSYRCVRDC-DPGYHAGPEG-TCDDV 939
+ + D +C D+DEC G +C S RC N PGS++C C GY P G C D+
Sbjct: 470 QLSDVDGVTCEDIDECALPTGGHIC-SYRCINIPGSFQC--SCPSSGYRLAPNGRNCQDI 526
Query: 940 DECQEYGPEICGA-QRCENTPGSYRCTP-ACDPGYQPTPGGGCQDVDECRNRSFCGAHAV 997
DEC G C + C N G +RC C Y+ + C+ R C +
Sbjct: 527 DECVT-GIHNCSINETCFNIQGGFRCLAFECPENYRRSAATRCE-------RLPCHENRE 578
Query: 998 CQNLP 1002
C LP
Sbjct: 579 CSKLP 583
Score = 219 bits (557), Expect = 2e-56
Identities = 153/411 (37%), Positives = 200/411 (48%), Gaps = 45/411 (10%)
Query: 653 PCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGR-CENTEGSFQCV 711
PC +C +T C+C G++ G C+DV+EC C G C NT GSF+C
Sbjct: 185 PCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQ 243
Query: 712 ----CPMGFQPNTAGSECEDVDECEN--HLACPGQECVNSPGSFQCRT---CPSGHHLHR 762
C G++ T + C+D+DECE+ H P C N+ GSF+CR C SG
Sbjct: 244 RDSSCGTGYEL-TEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDA 302
Query: 763 -GRCTDVDECSSGAPPCGPHGH-CTNTEGSFRC-----SCAPGYRAPSGRPGPCADVNEC 815
G C D++EC S + PC P GH C NTEGS+ C +C GY + C DV+EC
Sbjct: 303 LGNCIDINECLSISAPC-PIGHTCINTEGSYTCQKNVPNCGRGYHL-NEEGTRCVDVDEC 360
Query: 816 LE-GDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEED--LCQSGICTNTD 872
+ C C+N+ GSF C C GY C+DV+EC LC C NT
Sbjct: 361 APPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHK-CENTL 419
Query: 873 GSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGP 932
GS+ C C G R D SC D++EC + C SQ C N GSY+C C GY
Sbjct: 420 GSYLCSCSVGFRLSVDGRSCEDINECSS---SPC-SQECANVYGSYQCY--CRRGYQLSD 473
Query: 933 EG--TCDDVDECQ-EYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGG-GCQDVDECRN 988
TC+D+DEC G IC + RC N PGS++C+ GY+ P G CQD+DEC
Sbjct: 474 VDGVTCEDIDECALPTGGHIC-SYRCINIPGSFQCS-CPSSGYRLAPNGRNCQDIDECVT 531
Query: 989 RSF-CGAHAVCQNLPGSFQCL---CDQGYEGARDGR----HCVDVNECETL 1031
C + C N+ G F+CL C + Y + R C + EC L
Sbjct: 532 GIHNCSINETCFNIQGGFRCLAFECPENYRRSAATRCERLPCHENRECSKL 582
Score = 214 bits (545), Expect = 5e-55
Identities = 150/405 (37%), Positives = 194/405 (47%), Gaps = 44/405 (10%)
Query: 564 DECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRG-ACKN 622
D C R PC +C +T +C C GYQ G SC+DV+EC C G +C N
Sbjct: 178 DRC-RGGGPCKQ-QCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCIN 235
Query: 623 LPGSFRC----VCPAGF---RGSACEEDVDECAQEPPPCGPG-RCDNTAGSFHC----AC 670
GSFRC C G+ ++C +D+DEC C P C NT GSF C C
Sbjct: 236 TVGSFRCQRDSSCGTGYELTEDNSC-KDIDECESGIHNCLPDFICQNTLGSFRCRPKLQC 294
Query: 671 PAGFRSRGPGAPCQDVDECARSPPPCTYGR-CENTEGSFQCV-----CPMGFQPNTAGSE 724
+GF G C D++EC PC G C NTEGS+ C C G+ N G+
Sbjct: 295 KSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTR 353
Query: 725 CEDVDEC--ENHLACPGQECVNSPGSFQCRTCPSGHHLH--RGRCTDVDECSSGAPPCGP 780
C DVDEC G CVNSPGSF+C C +G++ C DV+EC P
Sbjct: 354 CVDVDECAPPAEPCGKGHRCVNSPGSFRCE-CKTGYYFDGISRMCVDVNECQ--RYPGRL 410
Query: 781 HGH-CTNTEGSFRCSCAPGYR-APSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTC 838
GH C NT GS+ CSC+ G+R + GR C D+NEC EC N GS+ C C
Sbjct: 411 CGHKCENTLGSYLCSCSVGFRLSVDGR--SCEDINECSSSPC---SQECANVYGSYQCYC 465
Query: 839 APGYR-PGPRGASCLDVDEC---SEEDLCQSGICTNTDGSFECICP-PGHRAGPDLASCL 893
GY+ G +C D+DEC + +C S C N GSF+C CP G+R P+ +C
Sbjct: 466 RRGYQLSDVDGVTCEDIDECALPTGGHIC-SYRCINIPGSFQCSCPSSGYRLAPNGRNCQ 524
Query: 894 DVDECRERGPALCGSQRCENSPGSYRCVR-DCDPGYHAGPEGTCD 937
D+DEC ++ C N G +RC+ +C Y C+
Sbjct: 525 DIDECVTGIHNCSINETCFNIQGGFRCLAFECPENYRRSAATRCE 569
Score = 209 bits (531), Expect = 2e-53
Identities = 139/401 (34%), Positives = 178/401 (44%), Gaps = 80/401 (19%)
Query: 490 GPGRCISRPSG--YTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGR-CENSPGSFRC- 545
GP + R +G C+C G++L G C DV+EC C G C N+ GSFRC
Sbjct: 184 GPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQ 243
Query: 546 ---VCGPG----------------------------------FRAGPR-----------A 557
CG G FR P+
Sbjct: 244 RDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDAL 303
Query: 558 AECLDVDECHRVPPPCDLGR-CENTPGSFLCV-----CPAGYQAAPHGASCQDVDECTQS 611
C+D++EC + PC +G C NT GS+ C C GY G C DVDEC
Sbjct: 304 GNCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPP 363
Query: 612 PGLCGRG-ACKNLPGSFRCVCPAGFRGSACEE---DVDECAQEPPPCGPGRCDNTAGSFH 667
CG+G C N PGSFRC C G+ DV+EC + P +C+NT GS+
Sbjct: 364 AEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYL 423
Query: 668 CACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQ-PNTAGSECE 726
C+C GFR G C+D++EC+ S PC+ C N GS+QC C G+Q + G CE
Sbjct: 424 CSCSVGFRLSVDGRSCEDINECSSS--PCSQ-ECANVYGSYQCYCRRGYQLSDVDGVTCE 480
Query: 727 DVDECE----NHLACPGQECVNSPGSFQCRTCPSGHHL-HRGR-CTDVDECSSGAPPCGP 780
D+DEC H+ C+N PGSFQC SG+ L GR C D+DEC +G C
Sbjct: 481 DIDECALPTGGHIC--SYRCINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSI 538
Query: 781 HGHCTNTEGSFRC---SCAPGYR---APSGRPGPCADVNEC 815
+ C N +G FRC C YR A PC + EC
Sbjct: 539 NETCFNIQGGFRCLAFECPENYRRSAATRCERLPCHENREC 579
Score = 195 bits (496), Expect = 3e-49
Identities = 133/360 (36%), Positives = 176/360 (48%), Gaps = 37/360 (10%)
Query: 729 DECENHLACPGQECVNSPGSFQCRTCPSGHHLHRG--RCTDVDECSSGAPPCGPHGHCTN 786
D C C Q+C ++ C +C G+ L C DV+EC +G+ C C N
Sbjct: 178 DRCRGGGPCK-QQCRDTGDEVVC-SCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCIN 235
Query: 787 TEGSFRC----SCAPGYRAPSGRPGPCADVNECLEGDF-CFPHGECLNTDGSFACT---- 837
T GSFRC SC GY C D++EC G C P C NT GSF C
Sbjct: 236 TVGSFRCQRDSSCGTGYELTEDNS--CKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQ 293
Query: 838 CAPGYRPGPRGASCLDVDEC-SEEDLCQSG-ICTNTDGSFECI-----CPPGHRAGPDLA 890
C G+ G +C+D++EC S C G C NT+GS+ C C G+ +
Sbjct: 294 CKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGT 352
Query: 891 SCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHA-GPEGTCDDVDECQEYGPEI 949
C+DVDEC RC NSPGS+RC +C GY+ G C DV+ECQ Y +
Sbjct: 353 RCVDVDECAPPAEPCGKGHRCVNSPGSFRC--ECKTGYYFDGISRMCVDVNECQRYPGRL 410
Query: 950 CGAQRCENTPGSYRCTPACDPGYQ-PTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCL 1008
CG +CENT GSY C+ C G++ G C+D++EC + S C C N+ GS+QC
Sbjct: 411 CG-HKCENTLGSYLCS--CSVGFRLSVDGRSCEDINECSS-SPCSQE--CANVYGSYQCY 464
Query: 1009 CDQGYE-GARDGRHCVDVNECETLQG--VCGAALCENVEGSFLCVCPNSPEEFDPMTGRC 1065
C +GY+ DG C D++EC G +C + C N+ GSF C CP+S P C
Sbjct: 465 CRRGYQLSDVDGVTCEDIDECALPTGGHIC-SYRCINIPGSFQCSCPSSGYRLAPNGRNC 523
Score = 190 bits (482), Expect = 1e-47
Identities = 109/273 (39%), Positives = 148/273 (54%), Gaps = 34/273 (12%)
Query: 494 CISRPSGYTCA-----CDSGFRLSPQGTRCIDVDECRRVPPPCAPG-RCENSPGSFRCVC 547
CI+ YTC C G+ L+ +GTRC+DVDEC PC G RC NSPGSFRC C
Sbjct: 325 CINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCEC 384
Query: 548 GPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDE 607
G+ + C+DV+EC R P +CENT GS+LC C G++ + G SC+D++E
Sbjct: 385 KTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINE 444
Query: 608 CTQSPGLCGRGACKNLPGSFRCVCPAGFR-----GSACEEDVDECAQEPPPCG----PGR 658
C+ SP C + C N+ GS++C C G++ G C ED+DECA P G R
Sbjct: 445 CSSSP--CSQ-ECANVYGSYQCYCRRGYQLSDVDGVTC-EDIDECAL---PTGGHICSYR 497
Query: 659 CDNTAGSFHCACP-AGFRSRGPGAPCQDVDECARSPPPCTYGR-CENTEGSFQCV---CP 713
C N GSF C+CP +G+R G CQD+DEC C+ C N +G F+C+ CP
Sbjct: 498 CINIPGSFQCSCPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECP 557
Query: 714 MGFQPNTAGSECEDVDECENHLACPGQECVNSP 746
++ +A + CE + EN +EC P
Sbjct: 558 ENYR-RSAATRCERLPCHEN------RECSKLP 583
Score = 145 bits (366), Expect = 3e-34
Identities = 84/234 (35%), Positives = 115/234 (49%), Gaps = 22/234 (9%)
Query: 482 CQRNPQVCGPG-RCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSP 540
C + CG G RC++ P + C C +G+ C+DV+EC+R P +CEN+
Sbjct: 360 CAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGHKCENTL 419
Query: 541 GSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAP-HG 599
GS+ C C GFR C D++EC PC C N GS+ C C GYQ + G
Sbjct: 420 GSYLCSCSVGFRLSVDGRSCEDINECS--SSPCS-QECANVYGSYQCYCRRGYQLSDVDG 476
Query: 600 ASCQDVDECTQSPG--LCGRGACKNLPGSFRCVCP-AGFR----GSACEEDVDECAQEPP 652
+C+D+DEC G +C C N+PGSF+C CP +G+R G C +D+DEC
Sbjct: 477 VTCEDIDECALPTGGHICSY-RCINIPGSFQCSCPSSGYRLAPNGRNC-QDIDECVTGIH 534
Query: 653 PCGPGR-CDNTAGSFHC---ACPAGFR----SRGPGAPCQDVDECARSPPPCTY 698
C C N G F C CP +R +R PC + EC++ P TY
Sbjct: 535 NCSINETCFNIQGGFRCLAFECPENYRRSAATRCERLPCHENRECSKLPLRITY 588
Score = 112 bits (279), Expect = 4e-24
Identities = 114/384 (29%), Positives = 146/384 (38%), Gaps = 75/384 (19%)
Query: 896 DECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEG-TCDDVDECQEYGPEICGAQR 954
D CR GP Q+C ++ C C GY +G +C+DV+EC +
Sbjct: 178 DRCRGGGPC---KQQCRDTGDEVVC--SCFVGYQLLSDGVSCEDVNECITGSHSCRLGES 232
Query: 955 CENTPGSYRCT--PACDPGYQPTPGGGCQDVDECRNRSF-CGAHAVCQNLPGSFQCL--- 1008
C NT GS+RC +C GY+ T C+D+DEC + C +CQN GSF+C
Sbjct: 233 CINTVGSFRCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKL 292
Query: 1009 -CDQGYEGARDGRHCVDVNECETLQGVCGAA-LCENVEGSFLCV--CPNSPEEF--DPMT 1062
C G+ G +C+D+NEC ++ C C N EGS+ C PN + +
Sbjct: 293 QCKSGFIQDALG-NCIDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEG 351
Query: 1063 GRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRREC----YF 1118
RCV A PP P GS R EC YF
Sbjct: 352 TRCVDVDECA---------------------PPAEPCGKGHRCVNSPGSFRCECKTGYYF 390
Query: 1119 DTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPS 1178
D I V EC G G C E LC G+ S
Sbjct: 391 D--------GISRMCVDVNECQRYPGRLCGHKC--------ENTLGSYLCSCSVGFRL-S 433
Query: 1179 GDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYY-HTQRLECIDNDECADEE 1237
D D++EC C S C N Y CYC GY + C D DECA
Sbjct: 434 VDGRSCEDINECS---SSPC-SQECANVYGSYQCYCRRGYQLSDVDGVTCEDIDECA--- 486
Query: 1238 PACEGG-----RCVNTVGSYHCTC 1256
GG RC+N GS+ C+C
Sbjct: 487 -LPTGGHICSYRCINIPGSFQCSC 509
Score = 70.9 bits (172), Expect = 9e-12
Identities = 48/146 (32%), Positives = 63/146 (43%), Gaps = 22/146 (15%)
Query: 1186 DVDECQLFRDQVCKSG-VCVNTAPGYSCY-----CSNGYYYHTQRLECIDNDECADE-EP 1238
D++EC L C G C+NT Y+C C GY+ + + C+D DECA EP
Sbjct: 308 DINEC-LSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEP 366
Query: 1239 ACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVS-NESQSLDDNLGVCWQEVGADLVCSHP 1297
+G RCVN+ GS+ C C+ DG R CV NE Q L C H
Sbjct: 367 CGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRL------------CGHK 414
Query: 1298 RLDRQATYTECCCLYGEAWGMDCALC 1323
+ +Y C C G +D C
Sbjct: 415 CENTLGSYL-CSCSVGFRLSVDGRSC 439
Score = 61.2 bits (147), Expect = 7e-09
Identities = 36/100 (36%), Positives = 46/100 (46%), Gaps = 3/100 (3%)
Query: 1171 GRGY-LAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECID 1229
GRGY L G + DVDEC + K CVN+ + C C GYY+ C+D
Sbjct: 342 GRGYHLNEEGTRCV--DVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVD 399
Query: 1230 NDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRC 1269
+EC G +C NT+GSY C+C L R C
Sbjct: 400 VNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSC 439
Score = 54.3 bits (129), Expect = 9e-07
Identities = 31/75 (41%), Positives = 34/75 (45%), Gaps = 8/75 (10%)
Query: 1467 AEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARC 1526
AE CG RCV P F C C GY D CVD+NEC LC +C
Sbjct: 364 AEPCG-----KGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGR--LC-GHKC 415
Query: 1527 LNTDGSFRCICRPGF 1541
NT GS+ C C GF
Sbjct: 416 ENTLGSYLCSCSVGF 430
Score = 52.4 bits (124), Expect = 3e-06
Identities = 30/84 (35%), Positives = 42/84 (50%), Gaps = 9/84 (10%)
Query: 1465 LEAEEC-GILDGCTNGR-CVRVPEGFTCR-----CFDGYRLDMTRMACVDINECDEAEAA 1517
++ EC I C G C+ +TC+ C GY L+ CVD++EC A A
Sbjct: 307 IDINECLSISAPCPIGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDEC--APPA 364
Query: 1518 SPLCVNARCLNTDGSFRCICRPGF 1541
P RC+N+ GSFRC C+ G+
Sbjct: 365 EPCGKGHRCVNSPGSFRCECKTGY 388
Score = 47.8 bits (112), Expect = 8e-05
Identities = 26/78 (33%), Positives = 39/78 (50%), Gaps = 7/78 (8%)
Query: 1465 LEAEECGILDGCTNG-RCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 1523
++ EC G G +C + C C G+RL + +C DINEC ++SP +
Sbjct: 398 VDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCEDINEC----SSSP--CS 451
Query: 1524 ARCLNTDGSFRCICRPGF 1541
C N GS++C CR G+
Sbjct: 452 QECANVYGSYQCYCRRGY 469
Score = 47.8 bits (112), Expect = 8e-05
Identities = 31/96 (32%), Positives = 41/96 (42%), Gaps = 13/96 (13%)
Query: 1452 GSYAGSLAEPYE--ELEAEECGILDGC---TNG-----RCVRVPEGFTCRC-FDGYRLDM 1500
GSY Y+ +++ C +D C T G RC+ +P F C C GYRL
Sbjct: 459 GSYQCYCRRGYQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAP 518
Query: 1501 TRMACVDINECDEAEAASPLCVNARCLNTDGSFRCI 1536
C DI+EC +N C N G FRC+
Sbjct: 519 NGRNCQDIDEC--VTGIHNCSINETCFNIQGGFRCL 552
Score = 46.2 bits (108), Expect = 2e-04
Identities = 27/77 (35%), Positives = 37/77 (48%), Gaps = 7/77 (9%)
Query: 1464 ELEAEECGILDGCTNG-----RCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAAS 1518
E E E+ + D C G +C + C CF GY+L ++C D+NEC +
Sbjct: 168 EEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSC 227
Query: 1519 PLCVNARCLNTDGSFRC 1535
L C+NT GSFRC
Sbjct: 228 RL--GESCINTVGSFRC 242
Score = 45.4 bits (106), Expect = 4e-04
Identities = 33/97 (34%), Positives = 45/97 (46%), Gaps = 11/97 (11%)
Query: 254 VHDCQLCSERLGNSER-VSAPDG---PCPTG--FERVNGSCEDVDECAT--GGRCQHGEC 305
V +C +E G R V++P C TG F+ ++ C DV+EC G C H +C
Sbjct: 357 VDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDVNECQRYPGRLCGH-KC 415
Query: 306 ANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPC 342
NT G Y C C GF L SC + + + PC
Sbjct: 416 ENTLGSYLCSCSVGFRLSVDGRSC--EDINECSSSPC 450
Score = 45.4 bits (106), Expect = 4e-04
Identities = 28/92 (30%), Positives = 45/92 (48%), Gaps = 8/92 (8%)
Query: 1452 GSYAGSLAEPYE-ELEAEECGILDGCTNG----RCVRVPEGFTCRCFDGYRL-DMTRMAC 1505
GSY S + + ++ C ++ C++ C V + C C GY+L D+ + C
Sbjct: 420 GSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTC 479
Query: 1506 VDINECDEAEAASPLCVNARCLNTDGSFRCIC 1537
DI+EC +C + RC+N GSF+C C
Sbjct: 480 EDIDEC-ALPTGGHIC-SYRCINIPGSFQCSC 509
Score = 44.7 bits (104), Expect = 7e-04
Identities = 30/101 (29%), Positives = 45/101 (44%), Gaps = 13/101 (12%)
Query: 253 GVHDCQ---LCSERLGNSERVSAPDGPCPTGF-ERVNGSCEDVDECAT-GGRCQHGE-CA 306
G+H+C +C LG+ P C +GF + G+C D++EC + C G C
Sbjct: 269 GIHNCLPDFICQNTLGSFR--CRPKLQCKSGFIQDALGNCIDINECLSISAPCPIGHTCI 326
Query: 307 NTRGGYTCV-----CPDGFLLDSSRSSCISQHVISEAKGPC 342
NT G YTC C G+ L+ + C+ + PC
Sbjct: 327 NTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPC 367
Score = 43.5 bits (101), Expect = 0.002
Identities = 31/100 (31%), Positives = 44/100 (44%), Gaps = 13/100 (13%)
Query: 253 GVHDCQL---CSERLGNSERVSAPDGPCPTGFERV-NGSCEDVDECATG--GRCQHGECA 306
G H C+L C +G+ D C TG+E + SC+D+DEC +G C
Sbjct: 223 GSHSCRLGESCINTVGSFR--CQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQ 280
Query: 307 NTRGGYTC----VCPDGFLLDSSRSSCISQHVISEAKGPC 342
NT G + C C GF+ D + +CI + PC
Sbjct: 281 NTLGSFRCRPKLQCKSGFIQD-ALGNCIDINECLSISAPC 319
Score = 41.6 bits (96), Expect = 0.006
Identities = 28/86 (32%), Positives = 36/86 (41%), Gaps = 15/86 (17%)
Query: 1462 YEELEAEECGILDGCTNGR--------CVRVPEGFTCR----CFDGYRLDMTRMACVDIN 1509
YE E C +D C +G C F CR C G+ D C+DIN
Sbjct: 252 YELTEDNSCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSGFIQDALGN-CIDIN 310
Query: 1510 ECDEAEAASPLCVNARCLNTDGSFRC 1535
EC A P + C+NT+GS+ C
Sbjct: 311 ECLSISAPCP--IGHTCINTEGSYTC 334
Score = 41.6 bits (96), Expect = 0.006
Identities = 28/76 (36%), Positives = 40/76 (52%), Gaps = 11/76 (14%)
Query: 254 VHDCQ-----LCSERLGNSERVSAPDGPCPTGFE-RVNG-SCEDVDECATGGRCQHGECA 306
V++CQ LC + N+ + + C GF V+G SCED++EC++ Q ECA
Sbjct: 400 VNECQRYPGRLCGHKCENT--LGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQ--ECA 455
Query: 307 NTRGGYTCVCPDGFLL 322
N G Y C C G+ L
Sbjct: 456 NVYGSYQCYCRRGYQL 471
Score = 41.2 bits (95), Expect = 0.008
Identities = 32/131 (24%), Positives = 54/131 (41%), Gaps = 16/131 (12%)
Query: 1140 CCTVG---EGWGSGCRIQQCPGTETAE-YQSLCPHGR--GYLAPSG----DLSLRRDVDE 1189
CC +G + G C G + + +++ C + G L G D + + ++
Sbjct: 112 CCLLGRAAQAQGQSCEYSLMVGYQCGQVFRACCVKSQETGDLDVGGLQETDKIIEVEEEQ 171
Query: 1190 CQLFRDQVCKSG-----VCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACE-GG 1243
+ + C+ G C +T C C GY + + C D +EC +C G
Sbjct: 172 EDPYLNDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGE 231
Query: 1244 RCVNTVGSYHC 1254
C+NTVGS+ C
Sbjct: 232 SCINTVGSFRC 242
Score = 38.9 bits (89), Expect = 0.039
Identities = 35/123 (28%), Positives = 56/123 (45%), Gaps = 17/123 (13%)
Query: 206 SAPREDGYSDASGFGYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLG 265
S+P ++ G C+ R G S + G+ +++ L G H C +
Sbjct: 447 SSPCSQECANVYGSYQCY--CRRGYQLSDVDGVTCEDI--DECALPTGGHICSYRCINIP 502
Query: 266 NSERVSAPDGPCPTGFERV--NG-SCEDVDECATG-GRCQHGE-CANTRGGYTCV---CP 317
S + S CP+ R+ NG +C+D+DEC TG C E C N +GG+ C+ CP
Sbjct: 503 GSFQCS-----CPSSGYRLAPNGRNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECP 557
Query: 318 DGF 320
+ +
Sbjct: 558 ENY 560
Score = 37.0 bits (84), Expect = 0.15
Identities = 23/59 (38%), Positives = 31/59 (52%), Gaps = 8/59 (13%)
Query: 277 CPTGFERVNG--SCEDVDECATGGR-CQHGE-CANTRGGYTC----VCPDGFLLDSSRS 327
C G++ ++ SCEDV+EC TG C+ GE C NT G + C C G+ L S
Sbjct: 201 CFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRCQRDSSCGTGYELTEDNS 259
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 233 bits (594), Expect = 1e-60
Identities = 252/922 (27%), Positives = 334/922 (36%), Gaps = 160/922 (17%)
Query: 474 ESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCA 532
E G S C + G GRC+ S C C GF QG RC DVDECR C
Sbjct: 120 EEGCLSAECSASLCFHG-GRCVPG-SAQPCHCPPGF----QGPRCQYDVDECRTHNGGCQ 173
Query: 533 PGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAG 592
RC N+PGS+ C C PGFR + CL ++ C C + T C C G
Sbjct: 174 H-RCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPG 232
Query: 593 YQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFR----GSACEEDVDECA 648
+Q G C C G C C+ + G RC C G++ G ACE DVDECA
Sbjct: 233 FQLQEDGRHCVRRSPCANRNGSCMH-RCQVVRGLARCECHVGYQLAADGKACE-DVDECA 290
Query: 649 QEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPC-----QDVDECARSPPPCTYGRCEN 703
C G C NT GSF C C AG+ G C + V+ C + C++G C +
Sbjct: 291 AGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHG-CSH 348
Query: 704 TEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRG 763
T C CP G++ +T C DVD+C + C Q C N+PG ++C C +G+ L
Sbjct: 349 TSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQ-QVCTNNPGGYECG-CYAGYRLSAD 406
Query: 764 RC--TDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNE---CLEG 818
C DVDEC+S C HCTN GSF+CSC GYR R G C+ + E L+G
Sbjct: 407 GCGCEDVDECASSRGGC--EHHCTNLAGSFQCSCEAGYRLHEDRRG-CSPLEEPMVDLDG 463
Query: 819 DFCF----PHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGS 874
+ F PH L + ++ GA + + E L + +C +
Sbjct: 464 ELPFVRPLPHIAVLQDE------LPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFG 517
Query: 875 FECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPG--SYRCVRDCDPGYHAGP 932
+C L D+CR G L G C+ G C C P
Sbjct: 518 HDC--------------SLTCDDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFG-- 561
Query: 933 EGTCDDVDECQEYG--PEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRS 990
C CQ G + GA RC C C GY CR +
Sbjct: 562 -KNCSFSCSCQNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYG---------KHCRKKC 611
Query: 991 FCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVD-------VNECETLQGVCGAALCENV 1043
C C L G+ CLCD G G C EC+ +Q C+
Sbjct: 612 NCANRGRCHRLYGA--CLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQP--HTQSCDKR 667
Query: 1044 EGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPV-LPARPPPPPLPRRPS 1102
+GS C C G G F QA PV + +R
Sbjct: 668 DGS--CSCKAG------FRGERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCP 719
Query: 1103 TPRQG-------PVGSGRRECYFDTAAPDA-CDNILAR-----NVTWQECCCTVGEG-WG 1148
QG PVG+ C + A C + + T ++C EG WG
Sbjct: 720 AGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWG 779
Query: 1149 SGCR--------IQQC----------PGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDEC 1190
GC+ +C PG + Q +CP G+ PS C
Sbjct: 780 LGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCP--AGWYGPSCQ-------TRC 830
Query: 1191 QLFRDQVCKSGV----CVNTAPGYSCY--CSNGYYYHTQRLECIDNDECADEEPACE--G 1242
D C C G+SC C G++ +C C+ +C+
Sbjct: 831 SCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHW----GPDCSHPCNCSAGHGSCDAIS 886
Query: 1243 GRCVNTVGSYHCTCEPPLVL----DGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHPR 1298
G C+ G CE G ++RC + D G C G
Sbjct: 887 GLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAG--------- 937
Query: 1299 LDRQATYTECCCLYGEAWGMDC 1320
+ T+ E C G +G+DC
Sbjct: 938 --WRGTFCEHACPAG-FFGLDC 956
Score = 209 bits (532), Expect = 2e-53
Identities = 254/985 (25%), Positives = 332/985 (33%), Gaps = 184/985 (18%)
Query: 455 PGPELPLPSIPAWTGP----EIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFR 510
PG P P + GP ++ E +G CQ RC++ P Y C C GFR
Sbjct: 141 PGSAQPCHCPPGFQGPRCQYDVDECRTHNGGCQH--------RCVNTPGSYLCECKPGFR 192
Query: 511 LSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVP 570
L C+ ++ C C + + RC C PGF+ C+ C
Sbjct: 193 LHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRN 252
Query: 571 PPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCV 630
C + RC+ G C C GYQ A G +C+DVDEC C G C N GSF+CV
Sbjct: 253 GSC-MHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHG-CLNTQGSFKCV 310
Query: 631 CPAGFR----GSACE----EDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAP 682
C AG+ G C E V+ C C G C +T+ C CP G+
Sbjct: 311 CHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHG-CSHTSAGPLCTCPRGYELDTDQRT 369
Query: 683 CQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQEC 742
C DVD+CA SP C C N G ++C C G++ + G CEDVDEC + C
Sbjct: 370 CIDVDDCADSP--CCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEHHC 427
Query: 743 VNSPGSFQCRTCPSGHHLHRGR--CTDVDE----CSSGAPPCGPHGHCTNTEGS----FR 792
N GSFQC +C +G+ LH R C+ ++E P P H + F+
Sbjct: 428 TNLAGSFQC-SCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQ 486
Query: 793 CSCAPGYRAPSGRPGP--------CAD---VNEC-LEGDFCFPHGECLNTDGSFACTCAP 840
+ G C D ++C L D C G CL G C C
Sbjct: 487 DDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGGTCLL--GLDGCDCPE 544
Query: 841 GYR---------PGPRGASCLDVDECSEEDLCQS--GICTNTDGSFECICPPGHRAGPDL 889
G+ P G +C C C S G C G C G G
Sbjct: 545 GWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYG 604
Query: 890 ASCLDVDECRERGPA--LCGSQRCENSPGSYR--CVRDCDPGYHAGPEGTCDDVDECQEY 945
C C RG L G+ C+ PG Y C C P + GP C + +C +
Sbjct: 605 KHCRKKCNCANRGRCHRLYGACLCD--PGLYGRFCHLTCPP-WAFGP--GCSEECQCVQP 659
Query: 946 GPEIC----GAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNL 1001
+ C G+ C+ RC C+ GY G GC C C ++
Sbjct: 660 HTQSCDKRDGSCSCKAGFRGERCQAECELGYF---GPGCWQA------CTCPVGVACDSV 710
Query: 1002 PGSFQCLCDQGYEGARDGRHC----VDVNECETLQGVCGAALCENVEGSFLC-------- 1049
G C G++G G+ C VN + CG A C V G C
Sbjct: 711 SGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCS--CGGAPCHGVTGQCRCPPGRTGED 768
Query: 1050 ----------------VCP--NSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPAR 1091
+CP DP TG C+ F GS+ Q V PA
Sbjct: 769 CEADCPEGRWGLGCQEICPACQHAARCDPETGACL----CLPGFVGSRCQ----DVCPAG 820
Query: 1092 PPPPPLPRRPSTPRQGPVGSGRREC-----YFDTAAPDACDNILARNVTWQECCCTVGEG 1146
P R S G C + + ACD C C+ G G
Sbjct: 821 WYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHG 880
Query: 1147 ----------------------------WGSGCRIQ-QCPGTETAEYQS---LCPHG-RG 1173
+G GC + QC ++ S CP G RG
Sbjct: 881 SCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRG 940
Query: 1174 ----YLAPSGDLSLR-RDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECI 1228
+ P+G L R C +G C+ A C+ HT C
Sbjct: 941 TFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNC- 999
Query: 1229 DNDECADEEPACEGGRCVNTVGSYHC-----------TCEPPLVLDGSQRRCVSNESQSL 1277
+ CA G C G HC C L D + C+ +
Sbjct: 1000 -SQACA----CFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTC 1054
Query: 1278 DDNLGVC-WQEVGADLVCSHPRLDR 1301
D G C E A L C L R
Sbjct: 1055 DPVSGHCACPEGWAGLACEKECLPR 1079
Score = 160 bits (404), Expect = 1e-38
Identities = 276/1091 (25%), Positives = 353/1091 (32%), Gaps = 217/1091 (19%)
Query: 36 FTPVVCGLRCVHGPTGSRCTPTCAPRNATSVDSGAPGGAAPGG-----------PGFRAF 84
+T ++C C G C+ +C+ +N + DS P G G+
Sbjct: 546 WTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGK 605
Query: 85 LCPLICH--NGGVCVKP-DRCLCPPDFAGKFCQLHSSGARPPAPAVPGLTRSVY-TMPLA 140
C C+ N G C + CLC P G+FC L PP PG + P
Sbjct: 606 HCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHL----TCPPWAFGPGCSEECQCVQPHT 661
Query: 141 NHRDDEHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAEAAARAEAAAPY 200
D G S + G +A+ E +A P
Sbjct: 662 QSCDKRDGSCSCKA-----------------GFRGERCQAECELGYFGPGCWQA-CTCPV 703
Query: 201 TVLAQSAPREDGYSDASGFGYCFRELRGGECASPLPGLRTQEVC-CRGAGLAWGVHDCQL 259
V S E G +GF E G EC G+ C C GA C+
Sbjct: 704 GVACDSVSGECGKRCPAGFQ---GEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRC 760
Query: 260 CSERLGNSERVSAPDGPCPTGFERVNGSCEDVDECATGGRCQHGECANTRG--GYTC--V 315
R G P+G G + + +C+ C + G C G G C V
Sbjct: 761 PPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDP----ETGACLCLPGFVGSRCQDV 816
Query: 316 CPDGFLLDS--SRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAW 373
CP G+ S +R SC + A G C C+ P + Q C + W
Sbjct: 817 CPAGWYGPSCQTRCSCANDGHCHPATGHC-------SCA-PGWTGFSCQRACDT---GHW 865
Query: 374 GRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRP 433
G C P C AG G + S L G PR
Sbjct: 866 GPDCS--HPCN-------CSAGHGSCDAISGL--CLCEAGYVGPRCEQQ----------- 903
Query: 434 SAGFLPTHRLEPRPEPRPDPRPGPELPLPS----IPA-WTGPEIPESGPSS--GMCQRNP 486
P P E R + G S PA W G + P+ G+ R+
Sbjct: 904 ----CPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSA 959
Query: 487 QVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPG-RCEN----SPG 541
C G +G +C C +G R G RC + C+ C N P
Sbjct: 960 CNCTAGAACDAVNG-SCLCPAGRR----GPRCAETCPAHTYGHNCSQACACFNGASCDPV 1014
Query: 542 SFRCVCGPGFRAGPRAAEC----LDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAP 597
+C C PG+ GP + L D C + G C+ P S C CP G+
Sbjct: 1015 HGQCHCAPGW-MGPSCLQACPAGLYGDNCRHSCLCQNGGTCD--PVSGHCACPEGWAGLA 1071
Query: 598 HGASCQDVD---ECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPC 654
C D C S G G C P + RC+CPAG+ G C+ PC
Sbjct: 1072 CEKECLPRDVRAGCRHSGGCLNGGLCD--PHTGRCLCPAGWTGDKCQS----------PC 1119
Query: 655 GPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPM 714
G C+CP PGA C V R PP T CE CP
Sbjct: 1120 LRGWFGEACAQ-RCSCP-------PGAACHHVTGACRCPPGFTGSGCEQ-------ACP- 1163
Query: 715 GFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSG 774
P + G +C + C+ CPG+ P + C +C +G+H C
Sbjct: 1164 ---PGSFGEDCAQM--CQ----CPGENPACHPATGTC-SCAAGYH--------GPSCQQR 1205
Query: 775 APP------------CGPHGHCTNTEGSFRCSCAPGY-------RAPSGRPGP-CADVNE 814
PP C G C G+ C C G+ P GR GP C V
Sbjct: 1206 CPPGRYGPGCEQLCGCLNGGSCDAATGA--CRCPTGFLGTDCNLTCPQGRFGPNCTHVCG 1263
Query: 815 CLEGDFCFP-HGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLC--QSGICTN- 870
C +G C P G CL G C G G C C LC +G C+
Sbjct: 1264 CGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGSCSCG 1323
Query: 871 ---TDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSY--RCVRDCD 925
T E CPPG A+C C + C PG Y C C
Sbjct: 1324 LGWTGRHCELACPPGRYG----AACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCP 1379
Query: 926 PGYH-AGPEGTCDDVDECQEYGP--EICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQD 982
PG+H AG +G C CQ P I G C + C C+PG + G G
Sbjct: 1380 PGFHGAGCQGLC----WCQHGAPCDPISGRCLCPAGFHGHFCERGCEPG---SFGEG--- 1429
Query: 983 VDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHC--VDVNECETLQGVC-GAAL 1039
C R C A C + G CLC G GA C TL C G A
Sbjct: 1430 ---CHQRCDCDGGAPCDPVTG--LCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGAD 1484
Query: 1040 CENVEGSFLCV 1050
C+ V G CV
Sbjct: 1485 CDPVSGQCHCV 1495
Score = 159 bits (403), Expect = 2e-38
Identities = 176/640 (27%), Positives = 232/640 (36%), Gaps = 107/640 (16%)
Query: 698 YGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSG 757
Y + TE C G+ C EC L G CV PGS Q CP G
Sbjct: 96 YRQVYTTEARTVLRCCRGWMQQPDEEGCLSA-ECSASLCFHGGRCV--PGSAQPCHCPPG 152
Query: 758 HHLHRGRCT-DVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECL 816
RC DVDEC + C C NT GS+ C C PG+R + C +N C
Sbjct: 153 --FQGPRCQYDVDECRTHNGGC--QHRCVNTPGSYLCECKPGFRLHTDSR-TCLAINSCA 207
Query: 817 EGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFE 876
G+ H T C C PG++ G C+ C+ + C G
Sbjct: 208 LGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLAR 267
Query: 877 CICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTC 936
C C G++ D +C DVDEC G A C + C N+ GS++CV C GY G +G
Sbjct: 268 CECHVGYQLAADGKACEDVDECAA-GLAQC-AHGCLNTQGSFKCV--CHAGYELGADGR- 322
Query: 937 DDVDECQEYGPEICGAQRCENTPGSYRCTPA-------CDPGYQ-PTPGGGCQDVDECRN 988
+C EI + N S+ C+ C GY+ T C DVD+C +
Sbjct: 323 ----QCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCAD 378
Query: 989 RSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFL 1048
C VC N PG ++C C GY + DG C DV+EC + +G C C N+ GSF
Sbjct: 379 SPCC--QQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGC-EHHCTNLAGSFQ 435
Query: 1049 CVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPL----PRRPSTP 1104
C C + G P +P LP P P + P
Sbjct: 436 CSCEAGYRLHE----------DRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLF 485
Query: 1105 RQGPVGSGRRE--------------CYFDTAAPD---ACDNILARN-----VTWQECCCT 1142
+ VG+ E C D+ D CD+ RN + C C
Sbjct: 486 QDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDD--CRNGGTCLLGLDGCDCP 543
Query: 1143 VGEGWGSGCRIQQCPGT---ETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCK 1199
EGW + CP + + C +G C D V
Sbjct: 544 --EGWTGLICNETCPPDTFGKNCSFSCSCQNG----------------GTC----DSVTG 581
Query: 1200 SGVCVNTAPGYSCY--CSNGYYYHTQRLECIDNDECADEEPACEG--GRCVNTVGSY--- 1252
+ C G +C C GYY R +C CA+ C G C+ G Y
Sbjct: 582 ACRCPPGVSGTNCEDGCPKGYYGKHCRKKC----NCAN-RGRCHRLYGACLCDPGLYGRF 636
Query: 1253 -HCTCEPPLVLDG--SQRRCVSNESQSLDDNLGVCWQEVG 1289
H TC P G + +CV +QS D G C + G
Sbjct: 637 CHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAG 676
Score = 152 bits (384), Expect = 2e-36
Identities = 293/1176 (24%), Positives = 381/1176 (32%), Gaps = 293/1176 (24%)
Query: 277 CPTGFERV--NGSCEDVDECATG-GRCQHGECANTRGGYTCVCPDGFLLDSSRSSC--IS 331
C G++ +CEDVDECA G +C HG C NT+G + CVC G+ L + C I
Sbjct: 270 CHVGYQLAADGKACEDVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQCYRIE 328
Query: 332 QHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPPF----GSEG 387
+++ + +GGCS +C C R G + C S
Sbjct: 329 MEIVNSCEA------NNGGCSHGCSHTSAGPLCTCPR-GYELDTDQRTCIDVDDCADSPC 381
Query: 388 FREICPAGPGYHYSASDLRYNTRPLG---QEPPRVSLSQPRTLPATSRPSAGFLPT---- 440
+++C PG + Y G ++ + S+ + + F +
Sbjct: 382 CQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAG 441
Query: 441 HRL-EPRPEPRPDPRPGPEL--------PLPSIPAWTGPEIPE--SGPSSGMCQRNPQVC 489
+RL E R P P +L PLP I A E+P+ G + ++
Sbjct: 442 YRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHI-AVLQDELPQLFQDDDVGADEEEAELR 500
Query: 490 GPGR------CISRPSGYTCA--CDSGFRLSPQGTRCIDVDEC------------RRVPP 529
G C+ G+ C+ CD GT + +D C PP
Sbjct: 501 GEHTLTEKFVCLDDSFGHDCSLTCDD---CRNGGTCLLGLDGCDCPEGWTGLICNETCPP 557
Query: 530 PCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVC 589
C SF C C G C V R PP CE+ C
Sbjct: 558 DTFGKNC-----SFSCSCQNG-------GTCDSVTGACRCPPGVSGTNCEDG-------C 598
Query: 590 PAGYQAAPHGASCQDVDECTQSPGLCGR--GACKNLPGSF----RCVCPAGFRGSACEED 643
P GY +G C+ C + G C R GAC PG + CP G C E+
Sbjct: 599 PKGY----YGKHCRKKCNCA-NRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEE 653
Query: 644 VDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYG---- 699
+C Q CD GS C+C AGFR G CQ E P C
Sbjct: 654 C-QCVQPHTQ----SCDKRDGS--CSCKAGFR----GERCQAECELGYFGPGCWQACTCP 702
Query: 700 ---RCENTEGSFQCVCPMGFQPNTAGSECEDVD---ECENHLACPGQECVNSPGSFQCRT 753
C++ G CP GFQ G EC C + +C G C G QCR
Sbjct: 703 VGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTG--QCR- 759
Query: 754 CPSGHHLHRGRCTDVD--------ECSSGAPPCGPHGHCTNTEGSFRCSCAPGY------ 799
CP G G + D C P C C G+ C C PG+
Sbjct: 760 CPPG---RTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGA--CLCLPGFVGSRCQ 814
Query: 800 -RAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECS 858
P+G GP C C G C G C+CAPG+ G SC
Sbjct: 815 DVCPAGWYGP-----SCQTRCSCANDGHCHPATGH--CSCAPGW----TGFSC------- 856
Query: 859 EEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSY 918
+ C +G D S C C GH SC A+ G CE
Sbjct: 857 -QRACDTG-HWGPDCSHPCNCSAGH------GSC----------DAISGLCLCEAGYVGP 898
Query: 919 RCVRDCDPGYHAGPEGTCDDVDECQEYG--PEICGAQRCENTPGSYR---CTPACDPGYQ 973
RC + C G H GP C+ +CQ + GA C P +R C AC G+
Sbjct: 899 RCEQQCPQG-HFGP--GCEQRCQCQHGAACDHVSGACTC---PAGWRGTFCEHACPAGFF 952
Query: 974 PTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETLQG 1033
+CR+ C A A C + GS CLC G G R C + T
Sbjct: 953 GL---------DCRSACNCTAGAACDAVNGS--CLCPAGRRGPR----CAETCPAHTYGH 997
Query: 1034 VCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPP 1093
C A C C N DP+ G+C P
Sbjct: 998 NCSQA----------CACFNG-ASCDPVHGQC--------------------HCAPGWMG 1026
Query: 1094 PPPLPRRPSTPRQGPVGSG-RRECYFDTAAPDACDNILARNVTWQECCCTVGEGW-GSGC 1151
P L P+ G G R C CD + C EGW G C
Sbjct: 1027 PSCLQACPA----GLYGDNCRHSCLCQNGG--TCDPVSGH--------CACPEGWAGLAC 1072
Query: 1152 RIQQCPGTETAEYQ--------SLC-PHGRGYLAPSGDLSLRRDVDECQ----------- 1191
+ P A + LC PH L P+G D+CQ
Sbjct: 1073 EKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTG-----DKCQSPCLRGWFGEA 1127
Query: 1192 LFRDQVCKSGVCVNTAPGYSCYCSNGYYYH---------TQRLECIDNDECADEEPACE- 1241
+ C G + G +C C G+ + +C +C E PAC
Sbjct: 1128 CAQRCSCPPGAACHHVTG-ACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHP 1186
Query: 1242 -GGRCVNTVGSYH---C--TCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVG-----A 1290
G C G YH C C P G ++ C S D G C G
Sbjct: 1187 ATGTCSCAAG-YHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDC 1245
Query: 1291 DLVCSHPRLDRQATYTECCCLYGEAWG--MDCALCP 1324
+L C R T+ C C G A LCP
Sbjct: 1246 NLTCPQGRFGPNCTHV-CGCGQGAACDPVTGTCLCP 1280
Score = 151 bits (381), Expect = 5e-36
Identities = 297/1142 (26%), Positives = 370/1142 (32%), Gaps = 295/1142 (25%)
Query: 215 DASGFGYCFRELRGGECASPLPGLRTQEVC--------------CRGAGLAWGVHDCQLC 260
D G C L G +C GL E C C+ G V C
Sbjct: 526 DCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRC 585
Query: 261 SERLGNSERVSAPDGPCPTGFERVNGSCEDVDECATGGRCQ--HGECANTRGGYTCVC-- 316
+ + + DG CP G+ C CA GRC +G C G Y C
Sbjct: 586 PPGVSGT---NCEDG-CPKGY--YGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHL 639
Query: 317 ---PDGFLLDSSRS-SCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKA 372
P F S C+ H S K RDG CS + C
Sbjct: 640 TCPPWAFGPGCSEECQCVQPHTQSCDK-------RDGSCSCKA--GFRGERCQAECELGY 690
Query: 373 WGRGC-QLCP-PFG------SEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQP 424
+G GC Q C P G S + CPAG + GQE P +
Sbjct: 691 FGPGCWQACTCPVGVACDSVSGECGKRCPAG-----------FQGEDCGQECPVGTFG-- 737
Query: 425 RTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQR 484
+ +S S G P H + + P R G + + PE G +
Sbjct: 738 --VNCSSSCSCGGAPCHGVTGQCRCPPG-RTGEDCEA---------DCPEGRWGLGCQEI 785
Query: 485 NPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPG-RCENS---- 539
P RC P C C GF G+RC DV P C C N
Sbjct: 786 CPACQHAARC--DPETGACLCLPGF----VGSRCQDVCPAGWYGPSCQTRCSCANDGHCH 839
Query: 540 PGSFRCVCGPGFRAGPRAAECLDVDECHRVPP---PCDL----GRCENTPGSFLCVCPAG 592
P + C C PG+ C D H P PC+ G C+ G LC+C AG
Sbjct: 840 PATGHCSCAPGWTGFSCQRAC---DTGHWGPDCSHPCNCSAGHGSCDAISG--LCLCEAG 894
Query: 593 YQAAPHGASCQDVDECTQS---PGL-----CGRGA-CKNLPGSFRCVCPAGFRGSACEED 643
Y G C+ +C Q PG C GA C ++ G+ C CPAG+RG+ CE
Sbjct: 895 YV----GPRCEQ--QCPQGHFGPGCEQRCQCQHGAACDHVSGA--CTCPAGWRGTFCEHA 946
Query: 644 VD------ECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCT 697
+C CD GS C CPAG RGP CA + P T
Sbjct: 947 CPAGFFGLDCRSACNCTAGAACDAVNGS--CLCPAG--RRGP--------RCAETCPAHT 994
Query: 698 YGRCENTEGSFQCVCPMGFQPNTAGSECEDV-DECENHLACPGQECVNSPGSFQCRTCPS 756
YG S C C G+ C+ V +C G C+ + CP+
Sbjct: 995 YGH----NCSQACAC-------FNGASCDPVHGQCHCAPGWMGPSCL--------QACPA 1035
Query: 757 GHHLHRGRCTDVDECSSGAPPCGP-HGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNEC 815
G L+ C C +G C P GHC EG +C R G C C
Sbjct: 1036 G--LYGDNCRHSCLCQNGG-TCDPVSGHCACPEGWAGLACEKECLPRDVRAG-CRHSGGC 1091
Query: 816 LEGDFCFPH-GECLNTDG----------------------------------SFACTCAP 840
L G C PH G CL G + AC C P
Sbjct: 1092 LNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPP 1151
Query: 841 GYR---------PGPRGASCLDVDEC-SEEDLCQ--SGICTNTDG----SFECICPPGHR 884
G+ PG G C + +C E C +G C+ G S + CPPG R
Sbjct: 1152 GFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPG-R 1210
Query: 885 AGP---DLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDE 941
GP L CL+ C A G+ RC C C G GP C V
Sbjct: 1211 YGPGCEQLCGCLNGGSC----DAATGACRCPTGFLGTDCNLTCPQG-RFGP--NCTHVCG 1263
Query: 942 CQEYG--PEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQ 999
C + + G C RC C Q G GC+ CRN C A
Sbjct: 1264 CGQGAACDPVTGTCLCPPGRAGVRCERGCP---QNRFGVGCEHTCSCRNGGLCHA----- 1315
Query: 1000 NLPGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFD 1059
+ C C G+ GRHC E G GAA C C N+ +
Sbjct: 1316 ---SNGSCSCGLGW----TGRHC----ELACPPGRYGAAC------HLECSCHNN-STCE 1357
Query: 1060 PMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSG-RRECYF 1118
P TG C R G F G + P P G G+G + C+
Sbjct: 1358 PATGTC---RCGPG-FYGQACEHPCPP--------------------GFHGAGCQGLCWC 1393
Query: 1119 DTAAPDACDNILARNVTWQECCCTVG------------EGWGSGCRIQ-QCPGTETAEYQ 1165
AP CD I R C C G +G GC + C G +
Sbjct: 1394 QHGAP--CDPISGR------CLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPV 1445
Query: 1166 S---LCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHT 1222
+ LCP GR + D + C L D C G + G C+C +GY T
Sbjct: 1446 TGLCLCPPGRSGATCNLDCRRGQFGPSCTLHCD--CGGGADCDPVSG-QCHCVDGYMGPT 1502
Query: 1223 QR 1224
R
Sbjct: 1503 CR 1504
Score = 147 bits (370), Expect = 1e-34
Identities = 293/1171 (25%), Positives = 395/1171 (33%), Gaps = 235/1171 (20%)
Query: 208 PREDGYSDAS-GFGYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGN 266
P E+G A CF GG C +PG C G +D C G
Sbjct: 118 PDEEGCLSAECSASLCFH---GGRC---VPGSAQPCHCPPGFQGPRCQYDVDECRTHNGG 171
Query: 267 SER--VSAPDG---PCPTGFERVNGS--CEDVDECATG-GRCQHGECANTRGGYTCVCPD 318
+ V+ P C GF S C ++ CA G G CQH T + C C
Sbjct: 172 CQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRP 231
Query: 319 GFLLDSSRSSCISQHVISEAKGPCF---RVLRD-GGCSLPILRNITKQICCCSRVGKAWG 374
GF L C+ + + G C +V+R C + + C V +
Sbjct: 232 GFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDEC-A 290
Query: 375 RGCQLCPP--FGSEG-FREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPAT- 430
G C ++G F+ +C AG Y G++ R+ + + A
Sbjct: 291 AGLAQCAHGCLNTQGSFKCVCHAG-----------YELGADGRQCYRIEMEIVNSCEANN 339
Query: 431 -------SRPSAGFLPTHRLEPRP-EPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMC 482
S SAG L T PR E D R ++ + S C
Sbjct: 340 GGCSHGCSHTSAGPLCTC---PRGYELDTDQRTCIDV--------------DDCADSPCC 382
Query: 483 QRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGS 542
Q QVC + P GY C C +G+RLS G C DVDEC C C N GS
Sbjct: 383 Q---QVC-----TNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGC-EHHCTNLAGS 433
Query: 543 FRCVCGPGFRAGPRAAECLDVDECHRVPPPCDL-GRCENT-PGSFLCV----CPAGYQAA 596
F+C C G+R C ++E P DL G P + V P +Q
Sbjct: 434 FQCSCEAGYRLHEDRRGCSPLEE-----PMVDLDGELPFVRPLPHIAVLQDELPQLFQDD 488
Query: 597 PHGASCQDVD--------------------ECTQSPGLCGRGACKNLPGSFRCVCPAGFR 636
GA ++ + +C+ + C G L G C CP G+
Sbjct: 489 DVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGG-TCLLGLDGCDCPEGWT 547
Query: 637 GSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPC 696
G C E PP C SF C+C G C V R PP
Sbjct: 548 GLICNETC------PPDTFGKNC-----SFSCSCQ-------NGGTCDSVTGACRCPPGV 589
Query: 697 TYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPG--QECVNSPGSFQCRTC 754
+ CE+ CP G+ G C C N C C+ PG + R C
Sbjct: 590 SGTNCEDG-------CPKGYY----GKHCRKKCNCANRGRCHRLYGACLCDPGLYG-RFC 637
Query: 755 PSGHHLHRGRCTDVDECSSGAPPCGPHGH-CTNTEGSFRCSCAPGYRAPS-------GRP 806
HL CS PH C +GS CSC G+R G
Sbjct: 638 ----HLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGS--CSCKAGFRGERCQAECELGYF 691
Query: 807 GPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASC----LDVDECSEEDL 862
GP C + C C + G C G++ G C V+ CS
Sbjct: 692 GP-----GCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVN-CSSSCS 745
Query: 863 CQSGICTNTDGSFECICPPGHRAGPDL-ASCLDVD---ECRERGPALCGSQRCENSPGSY 918
C C G +C CPPG R G D A C + C+E PA + RC+ G+
Sbjct: 746 CGGAPCHGVTG--QCRCPPG-RTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGAC 802
Query: 919 RCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENT----PGSYRCTPACDPGYQP 974
C+ PG+ C DV YGP C N P + C +C PG+
Sbjct: 803 LCL----PGFVG---SRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHC--SCAPGW-- 851
Query: 975 TPGGGCQDV-------DECRNRSFCGA-HAVCQNLPGSFQCLCDQGYEGARDGRHCVDVN 1026
G CQ +C + C A H C + G CLC+ GY G R + C +
Sbjct: 852 -TGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISG--LCLCEAGYVGPRCEQQCPQGH 908
Query: 1027 ---ECETLQGVCGAALCENVEGSFLCVCP-----NSPEEFDPMTGRCVPPRTSAGTFPGS 1078
CE A C++V G+ C CP E P + R++ G+
Sbjct: 909 FGPGCEQRCQCQHGAACDHVSGA--CTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGA 966
Query: 1079 QPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQE 1138
A L P R P P + C + AC N + + +
Sbjct: 967 ACDAVNGSCL-----CPAGRRGPRCAETCPAHTYGHNC----SQACACFNGASCDPVHGQ 1017
Query: 1139 CCCTVGEGWGSGCRIQQCPG---TETAEYQSLCPHG------RGYLA-PSGDLSLRRDVD 1188
C C GW +Q CP + + LC +G G+ A P G L +
Sbjct: 1018 CHC--APGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACE-K 1074
Query: 1189 ECQLFRD--QVCK-SGVCVN----TAPGYSCYCSNGYYYHTQRLECID---NDECADEEP 1238
EC L RD C+ SG C+N C C G+ + C+ + CA
Sbjct: 1075 EC-LPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCS 1133
Query: 1239 ACEGGRCVNTVGSYHCTCEPPLVLDGSQRRC 1269
G C + G+ C C P G ++ C
Sbjct: 1134 CPPGAACHHVTGA--CRCPPGFTGSGCEQAC 1162
Score = 128 bits (321), Expect = 5e-29
Identities = 145/517 (28%), Positives = 187/517 (36%), Gaps = 120/517 (23%)
Query: 830 TDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFE-CICPPGHRAGPD 888
T+ C G+ P CL ECS G C GS + C CPPG + GP
Sbjct: 102 TEARTVLRCCRGWMQQPDEEGCLSA-ECSASLCFHGGRCV--PGSAQPCHCPPGFQ-GPR 157
Query: 889 LASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEG-TCDDVDECQEYGP 947
DVDECR RC N+PGSY C +C PG+ + TC ++ C G
Sbjct: 158 CQ--YDVDECRTHNGGC--QHRCVNTPGSYLC--ECKPGFRLHTDSRTCLAINSCA-LGN 210
Query: 948 EICGAQRCENTPGSYRCTPACDPGYQ-PTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQ 1006
C + T +RC C PG+Q G C C NR+ H CQ + G +
Sbjct: 211 GGCQHHCVQLTITRHRCQ--CRPGFQLQEDGRHCVRRSPCANRNGSCMHR-CQVVRGLAR 267
Query: 1007 CLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCV 1066
C C GY+ A DG+ C DV+E C A L + G C N+ F +CV
Sbjct: 268 CECHVGYQLAADGKACEDVDE-------CAAGLAQCAHG-----CLNTQGSF-----KCV 310
Query: 1067 PPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECY-FDTAAPDA 1125
AG +G+ R+CY + ++
Sbjct: 311 ---CHAGY---------------------------------ELGADGRQCYRIEMEIVNS 334
Query: 1126 CDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRR 1185
C+ A N C G LC RGY + D
Sbjct: 335 CE---ANNGGCSHGCSHTSAG-------------------PLCTCPRGYELDT-DQRTCI 371
Query: 1186 DVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRC 1245
DVD+C D C VC N GY C C GY C D DECA CE C
Sbjct: 372 DVDDCA---DSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCE-HHC 427
Query: 1246 VNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLD------------------DNLGVCWQ- 1286
N GS+ C+CE L +R C E +D D L +Q
Sbjct: 428 TNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQD 487
Query: 1287 -EVGADLVCSHPRLDRQATYTECCCLYGEAWGMDCAL 1322
+VGAD L + T TE +++G DC+L
Sbjct: 488 DDVGADE--EEAELRGEHTLTEKFVCLDDSFGHDCSL 522
Score = 90.5 bits (223), Expect = 1e-17
Identities = 177/723 (24%), Positives = 231/723 (31%), Gaps = 187/723 (25%)
Query: 220 GYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGV---HDCQLCSERLGNSERVSAPD-- 274
G+C CA G Q C G WG H C CS G+ + +S
Sbjct: 836 GHCHPATGHCSCAPGWTGFSCQRACDTGH---WGPDCSHPCN-CSAGHGSCDAISGLCLC 891
Query: 275 -----GP-----CPTGFERVNGSCEDVDECATGGRCQH--GECANTRG--GYTC--VCPD 318
GP CP G CE +C G C H G C G G C CP
Sbjct: 892 EAGYVGPRCEQQCPQG--HFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPA 949
Query: 319 GFLLDSSRSSC--ISQHVISEAKGPCFRVLRDGG------CSLPILRNITKQICCC---S 367
GF RS+C + G C G C + Q C C +
Sbjct: 950 GFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGA 1009
Query: 368 RVGKAWGRGCQLCPPFGSEGFREICPAGP-GYHYSASDLRYNTRPLGQEPPRVSLSQ--- 423
G+ C P + + CPAG G + S L N + +
Sbjct: 1010 SCDPVHGQ-CHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWA 1068
Query: 424 ---------PRTLPATSRPSAGFLPTHRLEPRPEPRPDPR--PGPELPLPSIPAWTGPEI 472
PR + A R S G L +P P G + P + W G
Sbjct: 1069 GLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEAC 1128
Query: 473 PE--SGPSSGMCQRNPQVCGPGRCISRPSGYT-CACDSGFRLSPQGTRCIDVDECRRVPP 529
+ S P C V G RC P G+T C+ G C + +C P
Sbjct: 1129 AQRCSCPPGAACHH---VTGACRC---PPGFTGSGCEQACPPGSFGEDCAQMCQCPGENP 1182
Query: 530 PCAP--GRCENSPG----SFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPG 583
C P G C + G S + C PG R GP C ++ + G C+ G
Sbjct: 1183 ACHPATGTCSCAAGYHGPSCQQRCPPG-RYGPG---------CEQLCGCLNGGSCDAATG 1232
Query: 584 SFLCVCPAGYQAAPHGASCQDV---DECTQSPGLCGRGA-CKNLPGSFRCVCPAGFRGSA 639
+ C CP G+ +C CT G CG+GA C + G+ C+CP G G
Sbjct: 1233 A--CRCPTGFLGTDCNLTCPQGRFGPNCTHVCG-CGQGAACDPVTGT--CLCPPGRAGVR 1287
Query: 640 CEEDVDE------CAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSP 693
CE + C G C + GS C+C G+ R C +
Sbjct: 1288 CERGCPQNRFGVGCEHTCSCRNGGLCHASNGS--CSCGLGWTGR----------HCELAC 1335
Query: 694 PPCTYGR-------------CENTEGSFQC-----------VCPMGFQPNTAGSECEDVD 729
PP YG CE G+ +C CP GF G+ C+ +
Sbjct: 1336 PPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFH----GAGCQGLC 1391
Query: 730 ECENHLACPGQECVNSPGSFQCRTCPSGHHLH---RG--------RCTDVDECSSGAP-- 776
C++ C P S +C CP+G H H RG C +C GAP
Sbjct: 1392 WCQHGAPC-------DPISGRC-LCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCD 1443
Query: 777 --------PCGPHG------------------HCTNTEG------SFRCSCAPGYRAPSG 804
P G G HC G S +C C GY P+
Sbjct: 1444 PVTGLCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTC 1503
Query: 805 RPG 807
R G
Sbjct: 1504 REG 1506
Score = 56.2 bits (134), Expect = 2e-07
Identities = 73/304 (24%), Positives = 100/304 (32%), Gaps = 62/304 (20%)
Query: 89 ICHNGGVCV--KPDRCLCPPDFAGKFCQL-------HSSGARPPAPAVPGLTRSVYTMPL 139
+C +GG CV C CPP F G CQ H+ G + PG
Sbjct: 132 LCFHGGRCVPGSAQPCHCPPGFQGPRCQYDVDECRTHNGGCQHRCVNTPGSYLCECKPGF 191
Query: 140 ANHRDDEHGVASMVSVH-----VEHPQEASVVVHQVE-RVSGPWEEADAEAVARAEAA-- 191
H D +A H + ++ H+ + R +E V R+ A
Sbjct: 192 RLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANR 251
Query: 192 --------------ARAEAAAPYTVLAQSAPREDGYSDASGFGYCFRELRGGECASPLPG 237
AR E Y + A ED A+G +CA
Sbjct: 252 NGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLA---------QCAHGCLN 302
Query: 238 LRTQEVCCRGAGLAWG-------------VHDCQL----CSERLGNSERVSAPDGPCPTG 280
+ C AG G V+ C+ CS G S + P CP G
Sbjct: 303 TQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSH--GCSHTSAGPLCTCPRG 360
Query: 281 FERVNG--SCEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEA 338
+E +C DVD+CA CQ C N GGY C C G+ L + C + +
Sbjct: 361 YELDTDQRTCIDVDDCADSPCCQQ-VCTNNPGGYECGCYAGYRLSADGCGCEDVDECASS 419
Query: 339 KGPC 342
+G C
Sbjct: 420 RGGC 423
Score = 54.7 bits (130), Expect = 7e-07
Identities = 49/137 (35%), Positives = 58/137 (42%), Gaps = 21/137 (15%)
Query: 239 RTQEVCCRGAGLAWGVHDCQL--CSERL----GNSERVSAPDGPCPTGFERVNGSCE-DV 291
RT CCRG C CS L G SA CP GF+ C+ DV
Sbjct: 105 RTVLRCCRGWMQQPDEEGCLSAECSASLCFHGGRCVPGSAQPCHCPPGFQ--GPRCQYDV 162
Query: 292 DECAT-GGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGG 350
DEC T G CQH C NT G Y C C GF L + +C+ A C L +GG
Sbjct: 163 DECRTHNGGCQH-RCVNTPGSYLCECKPGFRLHTDSRTCL-------AINSC--ALGNGG 212
Query: 351 CSLPILR-NITKQICCC 366
C ++ IT+ C C
Sbjct: 213 CQHHCVQLTITRHRCQC 229
Score = 53.9 bits (128), Expect = 1e-06
Identities = 30/97 (30%), Positives = 38/97 (39%), Gaps = 3/97 (3%)
Query: 1461 PYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPL 1520
P + + +EC +G RCV P + C C G+RL C+ IN C
Sbjct: 156 PRCQYDVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGG--- 212
Query: 1521 CVNARCLNTDGSFRCICRPGFAPTHQPHHCAPARPRA 1557
C + T RC CRPGF HC P A
Sbjct: 213 CQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCA 249
Score = 53.9 bits (128), Expect = 1e-06
Identities = 26/77 (33%), Positives = 34/77 (44%), Gaps = 4/77 (5%)
Query: 1476 CTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRC 1535
C C P G+ C C+ GYRL C D++EC A+S C N GSF+C
Sbjct: 381 CCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDEC----ASSRGGCEHHCTNLAGSFQC 436
Query: 1536 ICRPGFAPTHQPHHCAP 1552
C G+ C+P
Sbjct: 437 SCEAGYRLHEDRRGCSP 453
Score = 52.4 bits (124), Expect = 3e-06
Identities = 60/213 (28%), Positives = 78/213 (36%), Gaps = 46/213 (21%)
Query: 1083 PASPVLPARPPPPPLPRRPSTPR----QGPVGSGRRECYFDTAAPDACDNILARNV-TWQ 1137
PA PV + PP P LP +P P Q GRR+ C L+ V W+
Sbjct: 24 PAVPVGASVPPRPLLPLQPGMPHVCAEQELTLVGRRQ---------PCVQALSHTVPVWK 74
Query: 1138 ECCCTVGEGWGSGC-----------RIQQCPGTETAEYQSLCPHGRGYLA-PSGDLSLRR 1185
C GW + C +Q TE C RG++ P + L
Sbjct: 75 AGC-----GWQAWCVGHERRTVYYMGYRQVYTTEARTVLRCC---RGWMQQPDEEGCLSA 126
Query: 1186 DVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLEC-IDNDECADEEPACEGGR 1244
+ F C G C+C G+ Q C D DEC C+ R
Sbjct: 127 ECSASLCFHGGRCVPG------SAQPCHCPPGF----QGPRCQYDVDECRTHNGGCQH-R 175
Query: 1245 CVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSL 1277
CVNT GSY C C+P L R C++ S +L
Sbjct: 176 CVNTPGSYLCECKPGFRLHTDSRTCLAINSCAL 208
Score = 50.8 bits (120), Expect = 1e-05
Identities = 27/72 (37%), Positives = 35/72 (48%), Gaps = 4/72 (5%)
Query: 1470 CGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNT 1529
C +G RC V C C GY+L AC D++EC A C + CLNT
Sbjct: 248 CANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDEC---AAGLAQCAHG-CLNT 303
Query: 1530 DGSFRCICRPGF 1541
GSF+C+C G+
Sbjct: 304 QGSFKCVCHAGY 315
Score = 49.3 bits (116), Expect = 3e-05
Identities = 24/67 (35%), Positives = 33/67 (49%), Gaps = 6/67 (8%)
Query: 1475 GCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFR 1534
GC++G C G C C GY LD + C+D+++C A SP C C N G +
Sbjct: 341 GCSHG-CSHTSAGPLCTCPRGYELDTDQRTCIDVDDC----ADSPCCQQV-CTNNPGGYE 394
Query: 1535 CICRPGF 1541
C C G+
Sbjct: 395 CGCYAGY 401
Score = 43.9 bits (102), Expect = 0.001
Identities = 43/150 (28%), Positives = 52/150 (34%), Gaps = 24/150 (16%)
Query: 1186 DVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDND-----ECADEEPAC 1240
DVDEC Q C G C+NT + C C GY +C + C C
Sbjct: 285 DVDECAAGLAQ-CAHG-CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGC 342
Query: 1241 EGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRLD 1300
G C +T CTC LD QR C+ +DD C AD C
Sbjct: 343 SHG-CSHTSAGPLCTCPRGYELDTDQRTCI-----DVDD----C-----ADSPCCQQVCT 387
Query: 1301 RQATYTECCCLYGEAWGMDCALCPAQDSDD 1330
EC C G D C +D D+
Sbjct: 388 NNPGGYECGCYAGYRLSADG--CGCEDVDE 415
Score = 33.9 bits (76), Expect = 1.3
Identities = 23/69 (33%), Positives = 28/69 (40%), Gaps = 14/69 (20%)
Query: 1450 EGGSYAGSLAEPYEELEAEECGI--LDGCTNGR------CVRVPEGFTCRCFDGYRLDMT 1501
E G YAG L A+ CG +D C + R C + F C C GYRL
Sbjct: 394 ECGCYAGY------RLSADGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHED 447
Query: 1502 RMACVDINE 1510
R C + E
Sbjct: 448 RRGCSPLEE 456
Score = 31.2 bits (69), Expect = 8.2
Identities = 21/79 (26%), Positives = 33/79 (41%), Gaps = 5/79 (6%)
Query: 1466 EAEECGI-LDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMAC--VDINECDEAEAASPLCV 1522
+ +EC L C +G C+ F C C GY L C +++ + EA + C
Sbjct: 285 DVDECAAGLAQCAHG-CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCS 343
Query: 1523 NARCLNTDGSFRCICRPGF 1541
+ C +T C C G+
Sbjct: 344 HG-CSHTSAGPLCTCPRGY 361
>gi|21704279 jagged 2 isoform b precursor [Homo sapiens]
Length = 1200
Score = 225 bits (574), Expect = 2e-58
Identities = 207/686 (30%), Positives = 279/686 (40%), Gaps = 142/686 (20%)
Query: 481 MCQRNPQVCGP-------GRCIS-RPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCA 532
+C ++ CG G CI+ P Y C C G+ G C + P
Sbjct: 303 LCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGY----SGRNCEKAEHACTSNPCAN 358
Query: 533 PGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLG-RCENTPGSFLCVCPA 591
G C P F C C G+ +GP A LD+DEC PC G C + F C+CP
Sbjct: 359 GGSCHEVPSGFECHCPSGW-SGPTCA--LDIDEC--ASNPCAAGGTCVDQVDGFECICPE 413
Query: 592 GYQAAPHGASCQ-DVDECTQSPGLCGRGA-CKNLPGSFRCVCPAGFRGSACEEDVDECAQ 649
+ GA+CQ DV++C G C G CK+L ++CVCP GF G CE + DECA
Sbjct: 414 QWV----GATCQLDVNDCR---GQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECAS 466
Query: 650 EPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQ-DVDECARSPPPCTYG-RCENTEGS 707
P G G C++ A FHC CP GF G C+ DVD C P PC G RC N EG
Sbjct: 467 SPCHSG-GLCEDLADGFHCHCPQGFS----GPLCEVDVDLC--EPSPCRNGARCYNLEGD 519
Query: 708 FQCVCPMGFQPNTA--------GSECEDVDECENHLACPGQ-------------ECVNSP 746
+ C CP F G C +D C + A PG CV+ P
Sbjct: 520 YYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSD-AGPGMPGTAASGVCGPHGRCVSQP 578
Query: 747 G-SFQCRTCPSGH---HLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAP 802
G +F C C SG + H ++D+C PC G C + +FRC C P
Sbjct: 579 GGNFSC-ICDSGFTGTYCHE----NIDDCLG--QPCRNGGTCIDEVDAFRCFC------P 625
Query: 803 SGRPGPCADVN--ECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVD-ECSE 859
SG G D N +CL D C G C + F C C G++ G +C + +C
Sbjct: 626 SGWEGELCDTNPNDCLP-DPCHSRGRCYDLVNDFYCACDDGWK----GKTCHSREFQCDA 680
Query: 860 EDLCQSGICTNTDGSFECICPPGHR----AGPDLASCLDVDECRERGPALCGSQRCENSP 915
G C ++ +F C CPPG + A +SCL P + G C S
Sbjct: 681 YTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLP-------NPCVNGGT-CVGSG 732
Query: 916 GSYRCVRDCDPGYHAGPEGTCD-DVDECQEYGPEIC-GAQRCENTPGSYRCTPACDPGYQ 973
S+ C+ C G+ TC + ++C P C C + +RC C PG+
Sbjct: 733 ASFSCI--CRDGWEGR---TCTHNTNDCN---PLPCYNGGICVDGVNWFRCE--CAPGFA 782
Query: 974 PTPGGGCQ-DVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGAR------DGRHC---- 1022
G C+ ++DEC++ S C A C + ++C C G G R GR C
Sbjct: 783 ---GPDCRINIDECQS-SPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSRG 838
Query: 1023 ----------VDVNECETLQG-------VCG--AALCENVEGSFLCVCPNSPEEFDPMTG 1063
D N C L G CG L + CP + G
Sbjct: 839 TPFPHGSSWVEDCNSCRCLDGRRDCSKVWCGWKPCLLAGQPEALSAQCPLGQRCLEKAPG 898
Query: 1064 RCVPPRTSAGTFPGSQPQAPASPVLP 1089
+C+ P A G++ + P++P LP
Sbjct: 899 QCLRPPCEAWGECGAE-EPPSTPCLP 923
Score = 192 bits (488), Expect = 2e-48
Identities = 177/617 (28%), Positives = 246/617 (39%), Gaps = 106/617 (17%)
Query: 467 WTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRR 526
W G E E+ G + PG C C G+ QG C DEC
Sbjct: 235 WMGKECKEAVCKQGCNLLHGGCTVPGEC---------RCSYGW----QGRFC---DEC-- 276
Query: 527 VP-PPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENT-PGS 584
VP P C G C ++C C + G + D++ C P + G C N P
Sbjct: 277 VPYPGCVHGSCVEP---WQCNCETNW--GGLLCD-KDLNYCGSHHPCTNGGTCINAEPDQ 330
Query: 585 FLCVCPAGYQAAPHGASCQDVDE-CTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEED 643
+ C CP GY G +C+ + CT +P G G+C +P F C CP+G+ G C D
Sbjct: 331 YRCTCPDGYS----GRNCEKAEHACTSNPCANG-GSCHEVPSGFECHCPSGWSGPTCALD 385
Query: 644 VDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQ-DVDECARSPPPCTY-GRC 701
+DECA P G G C + F C CP + GA CQ DV++C C + G C
Sbjct: 386 IDECASNPCAAG-GTCVDQVDGFECICP----EQWVGATCQLDVNDCRGQ---CQHGGTC 437
Query: 702 ENTEGSFQCVCPMGFQPNTAGSECE-DVDECENHLACPGQECVNSPGSFQCRTCPSGHHL 760
++ +QCVCP GF G CE + DEC + G C + F C CP G
Sbjct: 438 KDLVNGYQCVCPRGF----GGRHCELERDECASSPCHSGGLCEDLADGFHCH-CPQG--- 489
Query: 761 HRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGY--------RAPSGRPGPCADV 812
G +VD PC C N EG + C+C + R P G C +
Sbjct: 490 FSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPC-PGGACRVI 548
Query: 813 NEC-----------LEGDFCFPHGECLN-TDGSFACTCAPGYRPGPRGASCLD-VDECSE 859
+ C C PHG C++ G+F+C C G+ G C + +D+C
Sbjct: 549 DGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGF----TGTYCHENIDDCLG 604
Query: 860 EDLCQSGICTNTDGSFECICP---PGHRAGPDLASCLDVDECRERGPALCGSQRCENSPG 916
+ G C + +F C CP G + CL D C RG RC +
Sbjct: 605 QPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLP-DPCHSRG-------RCYDLVN 656
Query: 917 SYRCVRDCDPGYHAGPEGTCDDVD-ECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPT 975
+ C CD G+ TC + +C Y G C ++ ++RC AC PG++ +
Sbjct: 657 DFYCA--CDDGWKG---KTCHSREFQCDAYTCSNGGT--CYDSGDTFRC--ACPPGWKGS 707
Query: 976 PGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCV-DVNECETLQGV 1034
++ N C C SF C+C G+E GR C + N+C L
Sbjct: 708 TCAVAKNSSCLPNP--CVNGGTCVGSGASFSCICRDGWE----GRTCTHNTNDCNPLPCY 761
Query: 1035 CGAALCENVEGSFLCVC 1051
G +C + F C C
Sbjct: 762 NG-GICVDGVNWFRCEC 777
Score = 172 bits (436), Expect = 2e-42
Identities = 207/751 (27%), Positives = 275/751 (36%), Gaps = 187/751 (24%)
Query: 292 DECATGGRCQHGECANTRGGYTCVCPD---GFLLDSSRSSCISQHVISEAKGPCFRVLRD 348
DEC C HG C + C C G L D + C S H + G C D
Sbjct: 274 DECVPYPGCVHGSCVEP---WQCNCETNWGGLLCDKDLNYCGSHHPCTNG-GTCINAEPD 329
Query: 349 G-GCSLP---ILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREICPAGPGYHYSASD 404
C+ P RN K C+ A G C P GF CP+G A D
Sbjct: 330 QYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVP----SGFECHCPSGWSGPTCALD 385
Query: 405 LRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSI 464
+ S P T D G E P
Sbjct: 386 IDE------------CASNPCAAGGTC-------------------VDQVDGFECICPE- 413
Query: 465 PAWTGPEIP-ESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRC-IDVD 522
W G + G CQ G C +GY C C GF G C ++ D
Sbjct: 414 -QWVGATCQLDVNDCRGQCQHG------GTCKDLVNGYQCVCPRGFG----GRHCELERD 462
Query: 523 ECRRVPPPC-APGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLG-RCEN 580
EC PC + G CE+ F C C GF +GP +DVD C P PC G RC N
Sbjct: 463 EC--ASSPCHSGGLCEDLADGFHCHCPQGF-SGPLCE--VDVDLCE--PSPCRNGARCYN 515
Query: 581 TPGSFLCVCPAGY---------QAAPHGASCQDVDEC----------TQSPGLCG-RGAC 620
G + C CP + + P GA C+ +D C T + G+CG G C
Sbjct: 516 LEGDYYCACPDDFGGKNCSVPREPCPGGA-CRVIDGCGSDAGPGMPGTAASGVCGPHGRC 574
Query: 621 KNLPG-SFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGP 679
+ PG +F C+C +GF G+ C E++D+C +P G G C + +F C CP+G+
Sbjct: 575 VSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNG-GTCIDEVDAFRCFCPSGWE---- 629
Query: 680 GAPCQ-DVDECARSPPPC-TYGRCENTEGSFQCVCPMGFQPNTAGS---ECEDVDECEN- 733
G C + ++C P PC + GRC + F C C G++ T S +C D C N
Sbjct: 630 GELCDTNPNDCL--PDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQC-DAYTCSNG 686
Query: 734 ----------HLACP-----------------------GQECVNSPGSFQCRTCPSGHHL 760
ACP G CV S SF C C G
Sbjct: 687 GTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSC-ICRDGWE- 744
Query: 761 HRGR-CT-DVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEG 818
GR CT + ++C+ PC G C + FRC CAPG+ P R +++EC +
Sbjct: 745 --GRTCTHNTNDCNP--LPCYNGGICVDGVNWFRCECAPGFAGPDCR----INIDEC-QS 795
Query: 819 DFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECI 878
C C++ + C+C PG R GPR +E + C + F
Sbjct: 796 SPCAYGATCVDEINGYRCSCPPG-RAGPR----------CQEVIGFGRSCWSRGTPF--- 841
Query: 879 CPPGHRAGPDLASCLDVDECRERGPALCGSQRC----------ENSPGSYRCVRDCDPGY 928
P G D SC +D R+ CG + C P RC+ PG
Sbjct: 842 -PHGSSWVEDCNSCRCLDGRRDCSKVWCGWKPCLLAGQPEALSAQCPLGQRCLEKA-PGQ 899
Query: 929 HAGPEGTCDDVDECQEYGPEICGAQRCENTP 959
P C+ +G CGA+ +TP
Sbjct: 900 CLRP--------PCEAWGE--CGAEEPPSTP 920
Score = 152 bits (384), Expect = 2e-36
Identities = 191/753 (25%), Positives = 269/753 (35%), Gaps = 181/753 (24%)
Query: 631 CPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSF----HCACPAGFRSRGPGAPCQDV 686
C G+ G C+E V C G C+ G C C G++ R
Sbjct: 231 CMDGWMGKECKEAV---------CKQG-CNLLHGGCTVPGECRCSYGWQGRF-------C 273
Query: 687 DECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECE-DVDECENHLACP-GQECVN 744
DEC P C +G C +QC C + N G C+ D++ C +H C G C+N
Sbjct: 274 DECVPYPG-CVHGSCVEP---WQCNC----ETNWGGLLCDKDLNYCGSHHPCTNGGTCIN 325
Query: 745 S-PGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPS 803
+ P ++C TCP G+ GR + E + + PC G C F C C G+ P+
Sbjct: 326 AEPDQYRC-TCPDGYS---GRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPT 381
Query: 804 GRPGPCA-DVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASC-LDVDECSEED 861
CA D++EC C G C++ F C C + GA+C LDV++C +
Sbjct: 382 -----CALDIDECASNP-CAAGGTCVDQVDGFECICPEQWV----GATCQLDVNDCRGQ- 430
Query: 862 LCQ-SGICTNTDGSFECICPPGHRAGPDLASC-LDVDECRERGPALCGSQRCENSPGSYR 919
CQ G C + ++C+CP G C L+ DEC P G CE+ +
Sbjct: 431 -CQHGGTCKDLVNGYQCVCPRGFGG----RHCELERDECAS-SPCHSGGL-CEDLADGFH 483
Query: 920 CVRDCDPGYHAGPEGTCD-DVDECQEYGPEIC-GAQRCENTPGSYRCT-------PACDP 970
C C G+ +GP C+ DVD C+ P C RC N G Y C C
Sbjct: 484 C--HCPQGF-SGP--LCEVDVDLCE---PSPCRNGARCYNLEGDYYCACPDDFGGKNCSV 535
Query: 971 GYQPTPGGGCQDVDECRNRS-----------FCGAHAVCQNLPG-SFQCLCDQGYEGARD 1018
+P PGG C+ +D C + + CG H C + PG +F C+CD G+
Sbjct: 536 PREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFT---- 591
Query: 1019 GRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTG-RCVPPRTSAGTFPG 1077
G +C EN++ C N D + RC P G
Sbjct: 592 GTYCH-----------------ENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCD 634
Query: 1078 SQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQ 1137
+ P +C PD C +
Sbjct: 635 TNPN---------------------------------DCL-----PDPCHSRGRCYDLVN 656
Query: 1138 ECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRR-----DVDECQL 1192
+ C +GW + C E C +G G SGD C +
Sbjct: 657 DFYCACDDGWKG----KTCHSREFQCDAYTCSNG-GTCYDSGDTFRCACPPGWKGSTCAV 711
Query: 1193 FRDQVC------KSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCV 1246
++ C G CV + +SC C +G+ T C N + P GG CV
Sbjct: 712 AKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRT----CTHNTNDCNPLPCYNGGICV 767
Query: 1247 NTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDDNLG-VCWQEV-GADLVC----SHPRLD 1300
+ V + C C P G R +E QS G C E+ G C + PR
Sbjct: 768 DGVNWFRCECAPGFA--GPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQ 825
Query: 1301 RQATYTECCCL------YGEAWGMDCALCPAQD 1327
+ C +G +W DC C D
Sbjct: 826 EVIGFGRSCWSRGTPFPHGSSWVEDCNSCRCLD 858
Score = 122 bits (307), Expect = 2e-27
Identities = 147/583 (25%), Positives = 212/583 (36%), Gaps = 88/583 (15%)
Query: 699 GRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACP---GQECVNSPGSFQCR--T 753
G + E + C + T C ++ H C + C++ +C+
Sbjct: 185 GHVAHLELQIRVRCDENYYSATCNKFCRPRNDFFGHYTCDQYGNKACMDGWMGKECKEAV 244
Query: 754 CPSGHHLHRGRCTDVDECSSG-------APPCGP-----HGHCTNTEGSFRCSCAPGYRA 801
C G +L G CT EC C P HG C ++C+C +
Sbjct: 245 CKQGCNLLHGGCTVPGECRCSYGWQGRFCDECVPYPGCVHGSCVEP---WQCNCETNW-- 299
Query: 802 PSGRPGPCADVNECLEGDFCFPHGECLNTD-GSFACTCAPGYRPGPRGASCLDVDE-CSE 859
G D+N C C G C+N + + CTC GY G +C + C+
Sbjct: 300 --GGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYS----GRNCEKAEHACTS 353
Query: 860 EDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYR 919
G C FEC CP G +GP A LD+DEC A G+ C + +
Sbjct: 354 NPCANGGSCHEVPSGFECHCPSGW-SGPTCA--LDIDECASNPCAAGGT--CVDQVDGFE 408
Query: 920 CVRDCDPGYHAGPEGTCD-DVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGG 978
C+ C P G TC DV++C+ + C++ Y+C C G+ G
Sbjct: 409 CI--C-PEQWVG--ATCQLDVNDCRG---QCQHGGTCKDLVNGYQCV--CPRGFG---GR 455
Query: 979 GCQ-DVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHC-VDVNECETLQGVCG 1036
C+ + DEC + S C + +C++L F C C QG+ G C VDV+ CE G
Sbjct: 456 HCELERDECAS-SPCHSGGLCEDLADGFHCHCPQGFSGPL----CEVDVDLCEPSPCRNG 510
Query: 1037 AALCENVEGSFLCVCPNSPEEFDPMTGR-CVPPRTSAGTFPGSQPQAPASPVLPARPPPP 1095
A C N+EG + C CP D G+ C PR PG + A
Sbjct: 511 AR-CYNLEGDYYCACP------DDFGGKNCSVPREPC---PGGACRVIDGCGSDAG---- 556
Query: 1096 PLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQ 1155
P P T G G R C +C I T C + + G CR
Sbjct: 557 --PGMPGTAASGVCGPHGR-CVSQPGGNFSC--ICDSGFTGTYCHENIDDCLGQPCRNGG 611
Query: 1156 CPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCS 1215
E ++ CP G G+L D + D G C + + C C
Sbjct: 612 TCIDEVDAFRCFCPSGW-----EGELC---DTNPNDCLPDPCHSRGRCYDLVNDFYCACD 663
Query: 1216 NGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEP 1258
+G+ T C + D GG C ++ ++ C C P
Sbjct: 664 DGWKGKT----CHSREFQCDAYTCSNGGTCYDSGDTFRCACPP 702
Score = 122 bits (306), Expect = 3e-27
Identities = 183/746 (24%), Positives = 263/746 (35%), Gaps = 168/746 (22%)
Query: 90 CHNGGVCV--KPD--RCLCPPDFAGKFCQLHSSGARPPAPAVPGLTRSVYTMPLANHRDD 145
C NGG C+ +PD RC CP ++G+ C+ A H
Sbjct: 317 CTNGGTCINAEPDQYRCTCPDGYSGRNCEK------------------------AEHACT 352
Query: 146 EHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAEAAARAEAAAPYTVLAQ 205
+ A+ S H E P + H SGP D + A AA
Sbjct: 353 SNPCANGGSCH-EVP--SGFECHCPSGWSGPTCALDIDECASNPCAAG------------ 397
Query: 206 SAPREDGYSDASGFGYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLG 265
G C ++ G EC P + GA V+DC+ + G
Sbjct: 398 --------------GTCVDQVDGFECICPEQWV--------GATCQLDVNDCRGQCQHGG 435
Query: 266 N-SERVSAPDGPCPTGFERVNGSCE-DVDECATGGRCQHGECANTRGGYTCVCPDGF--- 320
+ V+ CP GF CE + DECA+ G C + G+ C CP GF
Sbjct: 436 TCKDLVNGYQCVCPRGFG--GRHCELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGP 493
Query: 321 LLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLC 380
L + C + A+ C+ + D C+ P + + C R G C++
Sbjct: 494 LCEVDVDLCEPSPCRNGAR--CYNLEGDYYCACP--DDFGGKNCSVPRE-PCPGGACRVI 548
Query: 381 PPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPT 440
GS+ AGPG +A+ P +SQP + S GF T
Sbjct: 549 DGCGSD-------AGPGMPGTAASGVCG-------PHGRCVSQPGGNFSCICDS-GFTGT 593
Query: 441 HRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGP------GRC 494
+ E + P + + A+ SG +C NP C P GRC
Sbjct: 594 YCHENIDDCLGQPCRNGGTCIDEVDAFRC--FCPSGWEGELCDTNPNDCLPDPCHSRGRC 651
Query: 495 ISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPG-RCENSPGSFRCVCGPGFRA 553
+ + CACD G++ +R D C+ G C +S +FRC C PG++
Sbjct: 652 YDLVNDFYCACDDGWKGKTCHSREFQCDAYT-----CSNGGTCYDSGDTFRCACPPGWKG 706
Query: 554 GPRAAECLDVDECHRVPPPC-DLGRCENTPGSFLCVCPAGYQAAPHGASC-QDVDECTQS 611
+ C +P PC + G C + SF C+C G++ G +C + ++C
Sbjct: 707 ----STCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWE----GRTCTHNTNDCNPL 758
Query: 612 PGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACP 671
P G G C + FRC C GF G C ++DEC P G C + + C+CP
Sbjct: 759 PCYNG-GICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYG-ATCVDEINGYRCSCP 816
Query: 672 AGFRSRGPGAPCQDV----DECARSPPPCTYG--------RCENTEGSFQC--------V 711
G G CQ+V C P +G C +G C
Sbjct: 817 PG----RAGPRCQEVIGFGRSCWSRGTPFPHGSSWVEDCNSCRCLDGRRDCSKVWCGWKP 872
Query: 712 CPMGFQPNTAGSECEDVDECENHLACPGQECV-NSPGSFQCRTCPSGHHLHRGRCTDVDE 770
C + QP ++C GQ C+ +PG QC P C E
Sbjct: 873 CLLAGQPEALSAQCP-----------LGQRCLEKAPG--QCLRPP---------CEAWGE 910
Query: 771 CSSGAPPCGPHGHCTNTEGSFRCSCA 796
C + PP P C G +CA
Sbjct: 911 CGAEEPPSTP---CLPRSGHLDNNCA 933
Score = 68.2 bits (165), Expect = 6e-11
Identities = 165/712 (23%), Positives = 228/712 (32%), Gaps = 224/712 (31%)
Query: 38 PVVCGLRCVHGPTGSRCT-------PTCAPRNATSVDSGAPGGAAPGGP------GFRAF 84
P G C P+G C PTCA +D A A GG GF
Sbjct: 355 PCANGGSCHEVPSGFECHCPSGWSGPTCA----LDIDECASNPCAAGGTCVDQVDGFECI 410
Query: 85 L---------------CPLICHNGGVC---VKPDRCLCPPDFAGKFCQLHSSGARPPAPA 126
C C +GG C V +C+CP F G+ C+L
Sbjct: 411 CPEQWVGATCQLDVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCH 470
Query: 127 VPGLTRSVYTMPLANHRDDEHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVA 186
GL + D H H + SGP E D +
Sbjct: 471 SGGLCEDL--------ADGFH-------------------CHCPQGFSGPLCEVDVDL-- 501
Query: 187 RAEAAARAEAAAPYTVLAQSAPREDGYSDASGFGYCFRELRGGECA---SPLPG--LRTQ 241
E + A Y + E Y A C + G C+ P PG R
Sbjct: 502 -CEPSPCRNGARCYNL-------EGDYYCA-----CPDDFGGKNCSVPREPCPGGACRVI 548
Query: 242 EVCCRGAGLAW-GVHDCQLCSERLGNSERVSAPDGP----CPTGFERVNGSC-EDVDECA 295
+ C AG G +C + VS P G C +GF C E++D+C
Sbjct: 549 DGCGSDAGPGMPGTAASGVCGP---HGRCVSQPGGNFSCICDSGF--TGTYCHENIDDC- 602
Query: 296 TGGRCQH-GECANTRGGYTCVCPDGF---LLDSSRSSCISQHVISEAKGPCFRVLRDGGC 351
G C++ G C + + C CP G+ L D++ + C+ ++G C+ ++ D C
Sbjct: 603 LGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDP--CHSRGRCYDLVNDFYC 660
Query: 352 SLP--------ILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREICPAGPGYHYSAS 403
+ R CS G + G + FR CP PG+ S
Sbjct: 661 ACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSG---------DTFRCACP--PGWKGSTC 709
Query: 404 DLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPS 463
+ N+ L P+P + S
Sbjct: 710 AVAKNSSCL--------------------------------------PNPCVNGGTCVGS 731
Query: 464 IPAWTGPEIPESGPSSGMCQRNPQVCGP------GRCISRPSGYTCACDSGFRLSPQGTR 517
+++ I G C N C P G C+ + + C C GF G
Sbjct: 732 GASFSC--ICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGF----AGPD 785
Query: 518 C-IDVDECRRVPPPCAPG-RCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDL 575
C I++DEC+ PCA G C + +RC C PG RAGPR E +
Sbjct: 786 CRINIDECQ--SSPCAYGATCVDEINGYRCSCPPG-RAGPRCQEVI------------GF 830
Query: 576 GRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNL------------ 623
GR C + PHG+S V++C L GR C +
Sbjct: 831 GRS----------CWSRGTPFPHGSSW--VEDCNSCRCLDGRRDCSKVWCGWKPCLLAGQ 878
Query: 624 PGSFRCVCPAGFR----------GSACEEDVDECAQEPP--PCGP--GRCDN 661
P + CP G R CE + A+EPP PC P G DN
Sbjct: 879 PEALSAQCPLGQRCLEKAPGQCLRPPCEAWGECGAEEPPSTPCLPRSGHLDN 930
Score = 44.7 bits (104), Expect = 7e-04
Identities = 25/78 (32%), Positives = 36/78 (46%), Gaps = 7/78 (8%)
Query: 1464 ELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 1523
ELE +EC + G C + +GF C C G+ + VD++ C+ SP
Sbjct: 458 ELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCE---VDVDLCE----PSPCRNG 510
Query: 1524 ARCLNTDGSFRCICRPGF 1541
ARC N +G + C C F
Sbjct: 511 ARCYNLEGDYYCACPDDF 528
Score = 42.4 bits (98), Expect = 0.004
Identities = 29/90 (32%), Positives = 40/90 (44%), Gaps = 15/90 (16%)
Query: 1449 PEGGSYAGSLAEPYEELEAEECGILDGCTNG-RCVRVPEGFTCRCFDGYRLDMTRMACVD 1507
P+G Y+G E +AE + C NG C VP GF C C G+ +D
Sbjct: 336 PDG--YSGRNCE-----KAEHACTSNPCANGGSCHEVPSGFECHCPSGW---SGPTCALD 385
Query: 1508 INECDEAEAASPLCVNARCLNTDGSFRCIC 1537
I+EC A++P C++ F CIC
Sbjct: 386 IDEC----ASNPCAAGGTCVDQVDGFECIC 411
Score = 38.9 bits (89), Expect = 0.039
Identities = 31/99 (31%), Positives = 38/99 (38%), Gaps = 13/99 (13%)
Query: 29 GERLRVRFTPVVCGLRCVHGPTGSRCTPTCAPRNATSVDSGAPGGAAPGGPGFRAFLC-- 86
G+ R P G C S C P T V SGA G+ C
Sbjct: 693 GDTFRCACPPGWKGSTCAVAKNSS-CLPNPCVNGGTCVGSGASFSCICRD-GWEGRTCTH 750
Query: 87 ------PLICHNGGVCVKP---DRCLCPPDFAGKFCQLH 116
PL C+NGG+CV RC C P FAG C+++
Sbjct: 751 NTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRIN 789
Score = 38.1 bits (87), Expect = 0.067
Identities = 23/74 (31%), Positives = 32/74 (43%), Gaps = 7/74 (9%)
Query: 1469 ECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLN 1528
+C L G CV F C C G+ R ++I+EC +SP A C++
Sbjct: 754 DCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCR---INIDECQ----SSPCAYGATCVD 806
Query: 1529 TDGSFRCICRPGFA 1542
+RC C PG A
Sbjct: 807 EINGYRCSCPPGRA 820
Score = 35.4 bits (80), Expect = 0.43
Identities = 27/85 (31%), Positives = 38/85 (44%), Gaps = 18/85 (21%)
Query: 1476 CTNG-RCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPL---CVNA-RCLNTD 1530
C+NG C + F C C G++ + C A+ +S L CVN C+ +
Sbjct: 683 CSNGGTCYDSGDTFRCACPPGWKG----------STCAVAKNSSCLPNPCVNGGTCVGSG 732
Query: 1531 GSFRCICRPGF---APTHQPHHCAP 1552
SF CICR G+ TH + C P
Sbjct: 733 ASFSCICRDGWEGRTCTHNTNDCNP 757
Score = 35.0 bits (79), Expect = 0.57
Identities = 30/115 (26%), Positives = 43/115 (37%), Gaps = 31/115 (26%)
Query: 1461 PYEELEAEECGILDGC------------------TNGRCVRVPEG-FTCRCFDGYRLDMT 1501
P E C ++DGC +GRCV P G F+C C G+ T
Sbjct: 536 PREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGF----T 591
Query: 1502 RMACVD-INECDEAEAASPLCVNARCLNTDGSFRCICRPGFAP---THQPHHCAP 1552
C + I++C P C++ +FRC C G+ P+ C P
Sbjct: 592 GTYCHENIDDC----LGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLP 642
Score = 32.7 bits (73), Expect = 2.8
Identities = 19/81 (23%), Positives = 32/81 (39%), Gaps = 8/81 (9%)
Query: 1465 LEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1524
L+ +EC G CV +GF C C + + + +D+N+C
Sbjct: 384 LDIDECASNPCAAGGTCVDQVDGFECICPEQW---VGATCQLDVNDC-----RGQCQHGG 435
Query: 1525 RCLNTDGSFRCICRPGFAPTH 1545
C + ++C+C GF H
Sbjct: 436 TCKDLVNGYQCVCPRGFGGRH 456
Score = 32.7 bits (73), Expect = 2.8
Identities = 28/88 (31%), Positives = 38/88 (43%), Gaps = 18/88 (20%)
Query: 1476 CTNG-RCVRVPEGFTCRC---FDGYRLDMTRM-----ACVDINECDE-------AEAASP 1519
C NG RC + + C C F G + R AC I+ C AAS
Sbjct: 507 CRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASG 566
Query: 1520 LC-VNARCLNTDG-SFRCICRPGFAPTH 1545
+C + RC++ G +F CIC GF T+
Sbjct: 567 VCGPHGRCVSQPGGNFSCICDSGFTGTY 594
Score = 31.2 bits (69), Expect = 8.2
Identities = 24/94 (25%), Positives = 39/94 (41%), Gaps = 14/94 (14%)
Query: 1468 EECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMAC-VDINECDEAEAASPLCVNARC 1526
+EC GC +G CV E + C C + + C D+N C + P C
Sbjct: 274 DECVPYPGCVHGSCV---EPWQCNC----ETNWGGLLCDKDLNYCG---SHHPCTNGGTC 323
Query: 1527 LNTD-GSFRCICRPGFAPTH--QPHHCAPARPRA 1557
+N + +RC C G++ + + H + P A
Sbjct: 324 INAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCA 357
>gi|21704277 jagged 2 isoform a precursor [Homo sapiens]
Length = 1238
Score = 221 bits (563), Expect = 4e-57
Identities = 210/680 (30%), Positives = 283/680 (41%), Gaps = 141/680 (20%)
Query: 482 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCAPG-RCENS 539
C NP G G C PSG+ C C SG+ G C +D+DEC PCA G C +
Sbjct: 351 CTSNPCANG-GSCHEVPSGFECHCPSGW----SGPTCALDIDEC--ASNPCAAGGTCVDQ 403
Query: 540 PGSFRCVCGPGFRAGPRAAEC-LDVDECHRVPPPC-DLGRCENTPGSFLCVCPAGYQAAP 597
F C+C P G A C LD +EC PC + C+N G + C C G++
Sbjct: 404 VDGFECIC-PEQWVG---ATCQLDANECEG--KPCLNAFSCKNLIGGYYCDCIPGWK--- 454
Query: 598 HGASCQ-DVDECTQSPGLCGRGA-CKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCG 655
G +C +V++C G C G CK+L ++CVCP GF G CE + DECA P G
Sbjct: 455 -GINCHINVNDCR---GQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSG 510
Query: 656 PGRCDNTAGSFHCACPAGFRSRGPGAPCQ-DVDECARSPPPCTYG-RCENTEGSFQCVCP 713
G C++ A FHC CP GF G C+ DVD C P PC G RC N EG + C CP
Sbjct: 511 -GLCEDLADGFHCHCPQGFS----GPLCEVDVDLC--EPSPCRNGARCYNLEGDYYCACP 563
Query: 714 MGFQPNTA--------GSECEDVDECENHLACPGQ-------------ECVNSPG-SFQC 751
F G C +D C + A PG CV+ PG +F C
Sbjct: 564 DDFGGKNCSVPREPCPGGACRVIDGCGSD-AGPGMPGTAASGVCGPHGRCVSQPGGNFSC 622
Query: 752 RTCPSGH---HLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGP 808
C SG + H ++D+C PC G C + +FRC C PSG G
Sbjct: 623 -ICDSGFTGTYCHE----NIDDCLG--QPCRNGGTCIDEVDAFRCFC------PSGWEGE 669
Query: 809 CADVN--ECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVD-ECSEEDLCQS 865
D N +CL D C G C + F C C G++ G +C + +C
Sbjct: 670 LCDTNPNDCLP-DPCHSRGRCYDLVNDFYCACDDGWK----GKTCHSREFQCDAYTCSNG 724
Query: 866 GICTNTDGSFECICPPGHR----AGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCV 921
G C ++ +F C CPPG + A +SCL P + G C S S+ C+
Sbjct: 725 GTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLP-------NPCVNGGT-CVGSGASFSCI 776
Query: 922 RDCDPGYHAGPEGTCD-DVDECQEYGPEIC-GAQRCENTPGSYRCTPACDPGYQPTPGGG 979
C G+ TC + ++C P C C + +RC C PG+ G
Sbjct: 777 --CRDGWEGR---TCTHNTNDCN---PLPCYNGGICVDGVNWFRCE--CAPGFA---GPD 823
Query: 980 CQ-DVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGAR------DGRHC---------- 1022
C+ ++DEC++ S C A C + ++C C G G R GR C
Sbjct: 824 CRINIDECQS-SPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHG 882
Query: 1023 ----VDVNECETLQG-------VCG--AALCENVEGSFLCVCPNSPEEFDPMTGRCVPPR 1069
D N C L G CG L + CP + G+C+ P
Sbjct: 883 SSWVEDCNSCRCLDGRRDCSKVWCGWKPCLLAGQPEALSAQCPLGQRCLEKAPGQCLRPP 942
Query: 1070 TSAGTFPGSQPQAPASPVLP 1089
A G++ + P++P LP
Sbjct: 943 CEAWGECGAE-EPPSTPCLP 961
Score = 201 bits (512), Expect = 3e-51
Identities = 178/591 (30%), Positives = 242/591 (40%), Gaps = 98/591 (16%)
Query: 481 MCQRNPQVCGP-------GRCIS-RPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCA 532
+C ++ CG G CI+ P Y C C G+ G C + P
Sbjct: 303 LCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGY----SGRNCEKAEHACTSNPCAN 358
Query: 533 PGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLG-RCENTPGSFLCVCPA 591
G C P F C C G+ +GP A LD+DEC PC G C + F C+CP
Sbjct: 359 GGSCHEVPSGFECHCPSGW-SGPTCA--LDIDEC--ASNPCAAGGTCVDQVDGFECICPE 413
Query: 592 GYQAAPHGASCQ-DVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQE 650
+ GA+CQ D +EC P L +CKNL G + C C G++G C +V++C +
Sbjct: 414 QWV----GATCQLDANECEGKPCL-NAFSCKNLIGGYYCDCIPGWKGINCHINVNDCRGQ 468
Query: 651 PPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQ-DVDECARSPPPC-TYGRCENTEGSF 708
G C + + C CP GF R C+ + DECA SP C + G CE+ F
Sbjct: 469 CQH--GGTCKDLVNGYQCVCPRGFGGRH----CELERDECASSP--CHSGGLCEDLADGF 520
Query: 709 QCVCPMGFQPNTAGSECE-DVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTD 767
C CP GF +G CE DVD CE G C N G + C CP G+
Sbjct: 521 HCHCPQGF----SGPLCEVDVDLCEPSPCRNGARCYNLEGDYYC-ACPDDFG---GK--- 569
Query: 768 VDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGEC 827
CS PC P G C +G G A G PG A C PHG C
Sbjct: 570 --NCSVPREPC-PGGACRVIDGC-------GSDAGPGMPGTAAS-------GVCGPHGRC 612
Query: 828 LNTDG-SFACTCAPGYRPGPRGASCLD-VDECSEEDLCQSGICTNTDGSFECICPPGHRA 885
++ G +F+C C G+ G C + +D+C + G C + +F C CP G
Sbjct: 613 VSQPGGNFSCICDSGFT----GTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEG 668
Query: 886 ---GPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVD-E 941
+ CL D C RG RC + + C CD G+ TC + +
Sbjct: 669 ELCDTNPNDCLP-DPCHSRG-------RCYDLVNDFYCA--CDDGWKGK---TCHSREFQ 715
Query: 942 CQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNL 1001
C Y G C ++ ++RC AC PG++ + ++ N C C
Sbjct: 716 CDAYTCSNGGT--CYDSGDTFRC--ACPPGWKGSTCAVAKNSSCLPNP--CVNGGTCVGS 769
Query: 1002 PGSFQCLCDQGYEGARDGRHCV-DVNECETLQGVCGAALCENVEGSFLCVC 1051
SF C+C G+E GR C + N+C L G +C + F C C
Sbjct: 770 GASFSCICRDGWE----GRTCTHNTNDCNPLPCYNG-GICVDGVNWFRCEC 815
Score = 171 bits (433), Expect = 5e-42
Identities = 210/763 (27%), Positives = 284/763 (37%), Gaps = 173/763 (22%)
Query: 292 DECATGGRCQHGECANTRGGYTCVCPD---GFLLDSSRSSCISQHVISEAKGPCFRVLRD 348
DEC C HG C + C C G L D + C S H + G C D
Sbjct: 274 DECVPYPGCVHGSCVEP---WQCNCETNWGGLLCDKDLNYCGSHHPCTNG-GTCINAEPD 329
Query: 349 G-GCSLP---ILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREICPA---GPGYHYS 401
C+ P RN K C+ A G C P GF CP+ GP
Sbjct: 330 QYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVP----SGFECHCPSGWSGPTCALD 385
Query: 402 ASDLRYNTRPLG-----QEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPG 456
+ N G Q + + + AT + A E +P +
Sbjct: 386 IDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDAN-------ECEGKPCLNAFSC 438
Query: 457 PELP----LPSIPAWTGPEIPES-GPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRL 511
L IP W G + G CQ G C +GY C C GF
Sbjct: 439 KNLIGGYYCDCIPGWKGINCHINVNDCRGQCQHG------GTCKDLVNGYQCVCPRGFG- 491
Query: 512 SPQGTRC-IDVDECRRVPPPC-APGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRV 569
G C ++ DEC PC + G CE+ F C C GF +GP +DVD C
Sbjct: 492 ---GRHCELERDEC--ASSPCHSGGLCEDLADGFHCHCPQGF-SGPLCE--VDVDLCE-- 541
Query: 570 PPPCDLG-RCENTPGSFLCVCPAGY---------QAAPHGASCQDVDEC----------T 609
P PC G RC N G + C CP + + P GA C+ +D C T
Sbjct: 542 PSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGA-CRVIDGCGSDAGPGMPGT 600
Query: 610 QSPGLCG-RGACKNLPG-SFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFH 667
+ G+CG G C + PG +F C+C +GF G+ C E++D+C +P G G C + +F
Sbjct: 601 AASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNG-GTCIDEVDAFR 659
Query: 668 CACPAGFRSRGPGAPCQ-DVDECARSPPPC-TYGRCENTEGSFQCVCPMGFQPNTAGS-- 723
C CP+G+ G C + ++C P PC + GRC + F C C G++ T S
Sbjct: 660 CFCPSGWE----GELCDTNPNDCL--PDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSRE 713
Query: 724 -ECEDVDECEN-----------HLACP-----------------------GQECVNSPGS 748
+C D C N ACP G CV S S
Sbjct: 714 FQC-DAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGAS 772
Query: 749 FQCRTCPSGHHLHRGR-CT-DVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRP 806
F C C G GR CT + ++C+ PC G C + FRC CAPG+ P R
Sbjct: 773 FSC-ICRDGWE---GRTCTHNTNDCNP--LPCYNGGICVDGVNWFRCECAPGFAGPDCR- 825
Query: 807 GPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSG 866
+++EC + C C++ + C+C PG R GPR +E +
Sbjct: 826 ---INIDEC-QSSPCAYGATCVDEINGYRCSCPPG-RAGPR----------CQEVIGFGR 870
Query: 867 ICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRC----------ENSPG 916
C + F P G D SC +D R+ CG + C P
Sbjct: 871 SCWSRGTPF----PHGSSWVEDCNSCRCLDGRRDCSKVWCGWKPCLLAGQPEALSAQCPL 926
Query: 917 SYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTP 959
RC+ PG P C+ +G CGA+ +TP
Sbjct: 927 GQRCLEKA-PGQCLRP--------PCEAWGE--CGAEEPPSTP 958
Score = 167 bits (424), Expect = 6e-41
Identities = 201/781 (25%), Positives = 281/781 (35%), Gaps = 173/781 (22%)
Query: 599 GASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGR 658
G C++ C Q L G C +PG C C G++G C DEC P C G
Sbjct: 237 GKECKEA-VCKQGCNLL-HGGC-TVPGE--CRCSYGWQGRFC----DECVPYPG-CVHGS 286
Query: 659 CDNTAGSFHCACPAGFRSRGPGAPC-QDVDECARSPPPCTYGRCENTE-GSFQCVCPMGF 716
C + C C + G C +D++ C P G C N E ++C CP G+
Sbjct: 287 C---VEPWQCNCETNWG----GLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGY 339
Query: 717 QPNTAGSECEDVDE-CENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCT-DVDECSSG 774
+G CE + C ++ G C P F+C CPSG C D+DEC+S
Sbjct: 340 ----SGRNCEKAEHACTSNPCANGGSCHEVPSGFECH-CPSGWS--GPTCALDIDECASN 392
Query: 775 APPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSF 834
PC G C + F C C + + + D NEC EG C C N G +
Sbjct: 393 --PCAAGGTCVDQVDGFECICPEQWVGATCQ----LDANEC-EGKPCLNAFSCKNLIGGY 445
Query: 835 ACTCAPGYRPGPRGASC-LDVDECSEEDLCQ-SGICTNTDGSFECICPPGHRAGPDLASC 892
C C PG++ G +C ++V++C + CQ G C + ++C+CP G C
Sbjct: 446 YCDCIPGWK----GINCHINVNDCRGQ--CQHGGTCKDLVNGYQCVCPRGFGG----RHC 495
Query: 893 -LDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCD-DVDECQEYGPEIC 950
L+ DEC P G CE+ + C C G+ +GP C+ DVD C+ P C
Sbjct: 496 ELERDECAS-SPCHSGGL-CEDLADGFHC--HCPQGF-SGP--LCEVDVDLCE---PSPC 545
Query: 951 -GAQRCENTPGSYRCT-------PACDPGYQPTPGGGCQDVDECRNRS-----------F 991
RC N G Y C C +P PGG C+ +D C + +
Sbjct: 546 RNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGV 605
Query: 992 CGAHAVCQNLPG-SFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCV 1050
CG H C + PG +F C+CD G+ G +C EN++
Sbjct: 606 CGPHGRCVSQPGGNFSCICDSGFT----GTYCH-----------------ENIDDCLGQP 644
Query: 1051 CPNSPEEFDPMTG-RCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPV 1109
C N D + RC P G + P
Sbjct: 645 CRNGGTCIDEVDAFRCFCPSGWEGELCDTNPN---------------------------- 676
Query: 1110 GSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCP 1169
+C PD C + + C +GW + C E C
Sbjct: 677 -----DCL-----PDPCHSRGRCYDLVNDFYCACDDGWKG----KTCHSREFQCDAYTCS 722
Query: 1170 HGRGYLAPSGDLSLRR-----DVDECQLFRDQVC------KSGVCVNTAPGYSCYCSNGY 1218
+G G SGD C + ++ C G CV + +SC C +G+
Sbjct: 723 NG-GTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGW 781
Query: 1219 YYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLD 1278
T C N + P GG CV+ V + C C P G R +E QS
Sbjct: 782 EGRT----CTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFA--GPDCRINIDECQSSP 835
Query: 1279 DNLG-VCWQEV-GADLVC----SHPRLDRQATYTECCCL------YGEAWGMDCALCPAQ 1326
G C E+ G C + PR + C +G +W DC C
Sbjct: 836 CAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHGSSWVEDCNSCRCL 895
Query: 1327 D 1327
D
Sbjct: 896 D 896
Score = 145 bits (365), Expect = 4e-34
Identities = 156/586 (26%), Positives = 233/586 (39%), Gaps = 121/586 (20%)
Query: 277 CPTGFERVNGSCE-DVDECATGGRCQHGECANTRGGYTCVCPDGFL-----LDSSRS--- 327
CP+G+ +C D+DECA+ G C + G+ C+CP+ ++ LD++
Sbjct: 373 CPSGWS--GPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDANECEGK 430
Query: 328 ------SC-----------------ISQHV-ISEAKGPCFRVLRDGGCSLPILRNITKQI 363
SC I+ H+ +++ +G C + GG ++
Sbjct: 431 PCLNAFSCKNLIGGYYCDCIPGWKGINCHINVNDCRGQC----QHGGTCKDLVNGYQ--- 483
Query: 364 CCCSRVGKAWGRGCQLCPPFGSEGFREICPAGP----GYHYSASDLRYNTRPLGQEPPRV 419
C C R GR C+L R+ C + P G +D + P G P
Sbjct: 484 CVCPR--GFGGRHCEL--------ERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLC 533
Query: 420 SLSQPRTLPATSRPSAGFLPTHRLEPRPE-PRPDPRPGPELPLPSIP------------- 465
+ P+ R A + LE PD G +P P
Sbjct: 534 EVDVDLCEPSPCRNGA---RCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCG 590
Query: 466 AWTGPEIPESGPSSGMCQRNPQVCGP-GRCISRPSG-YTCACDSGFRLSPQGTRCID-VD 522
+ GP +P + S VCGP GRC+S+P G ++C CDSGF GT C + +D
Sbjct: 591 SDAGPGMPGTAASG--------VCGPHGRCVSQPGGNFSCICDSGF----TGTYCHENID 638
Query: 523 ECRRVPPPCA-PGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPC-DLGRCEN 580
+C + PC G C + +FRC C G+ E D + +P PC GRC +
Sbjct: 639 DC--LGQPCRNGGTCIDEVDAFRCFCPSGWE-----GELCDTNPNDCLPDPCHSRGRCYD 691
Query: 581 TPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSAC 640
F C C G++ G +C + + G C + +FRC CP G++GS C
Sbjct: 692 LVNDFYCACDDGWK----GKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTC 747
Query: 641 EEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPC-TYG 699
+ P G C + SF C C G+ R + ++C +P PC G
Sbjct: 748 AVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGR---TCTHNTNDC--NPLPCYNGG 802
Query: 700 RCENTEGSFQCVCPMGFQPNTAGSECE-DVDECENHLACPGQECVNSPGSFQCRTCPSGH 758
C + F+C C GF AG +C ++DEC++ G CV+ ++C +CP G
Sbjct: 803 ICVDGVNWFRCECAPGF----AGPDCRINIDECQSSPCAYGATCVDEINGYRC-SCPPGR 857
Query: 759 HLHRGRCTDV----DECSSGAPPCGPHGHCTNTEGSFRCSCAPGYR 800
RC +V C S P PHG + E C C G R
Sbjct: 858 --AGPRCQEVIGFGRSCWSRGTPF-PHG-SSWVEDCNSCRCLDGRR 899
Score = 120 bits (300), Expect = 1e-26
Identities = 182/757 (24%), Positives = 267/757 (35%), Gaps = 152/757 (20%)
Query: 90 CHNGGVCV--KPD--RCLCPPDFAGKFCQLHSSGARPPAPAVPGLTRSVYTMPLANHRDD 145
C NGG C+ +PD RC CP ++G+ C+ A H
Sbjct: 317 CTNGGTCINAEPDQYRCTCPDGYSGRNCE------------------------KAEHACT 352
Query: 146 EHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAEAAARA---------EA 196
+ A+ S H E P + H SGP D + A AA E
Sbjct: 353 SNPCANGGSCH-EVP--SGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFEC 409
Query: 197 AAPYTVLAQSAPREDGYSDASGF--GYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGV 254
P + + + + + + L GG +PG +G V
Sbjct: 410 ICPEQWVGATCQLDANECEGKPCLNAFSCKNLIGGYYCDCIPG-------WKGINCHINV 462
Query: 255 HDCQ-LCSERLGNSERVSAPDGPCPTGFERVNGSCE-DVDECATGGRCQHGECANTRGGY 312
+DC+ C + V+ CP GF CE + DECA+ G C + G+
Sbjct: 463 NDCRGQCQHGGTCKDLVNGYQCVCPRGFG--GRHCELERDECASSPCHSGGLCEDLADGF 520
Query: 313 TCVCPDGF---LLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRV 369
C CP GF L + C + A+ C+ + D C+ P + + C R
Sbjct: 521 HCHCPQGFSGPLCEVDVDLCEPSPCRNGAR--CYNLEGDYYCACP--DDFGGKNCSVPR- 575
Query: 370 GKAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPA 429
G C++ GS+ AGPG +A+ P +SQP
Sbjct: 576 EPCPGGACRVIDGCGSD-------AGPGMPGTAASGVCG-------PHGRCVSQPGG-NF 620
Query: 430 TSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVC 489
+ +GF T+ E + P + + A+ SG +C NP C
Sbjct: 621 SCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRC--FCPSGWEGELCDTNPNDC 678
Query: 490 GP------GRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCA-PGRCENSPGS 542
P GRC + + CACD G++ +R D C+ G C +S +
Sbjct: 679 LPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAY-----TCSNGGTCYDSGDT 733
Query: 543 FRCVCGPGFRAGPRAAECLDVDECHRVPPPC-DLGRCENTPGSFLCVCPAGYQAAPHGAS 601
FRC C PG+ + + C +P PC + G C + SF C+C G++ G +
Sbjct: 734 FRCACPPGW----KGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWE----GRT 785
Query: 602 C-QDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCD 660
C + ++C P G G C + FRC C GF G C ++DEC P G C
Sbjct: 786 CTHNTNDCNPLPCYNG-GICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYG-ATCV 843
Query: 661 NTAGSFHCACPAGFRSRGPGAPCQDV----DECARSPPPCTYG--------RCENTEGSF 708
+ + C+CP G G CQ+V C P +G C +G
Sbjct: 844 DEINGYRCSCPPG----RAGPRCQEVIGFGRSCWSRGTPFPHGSSWVEDCNSCRCLDGRR 899
Query: 709 QC--------VCPMGFQPNTAGSECEDVDECENHLACPGQECV-NSPGSFQCRTCPSGHH 759
C C + QP ++C GQ C+ +PG QC P
Sbjct: 900 DCSKVWCGWKPCLLAGQPEALSAQCP-----------LGQRCLEKAPG--QCLRPP---- 942
Query: 760 LHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCA 796
C EC + PP P C G +CA
Sbjct: 943 -----CEAWGECGAEEPPSTP---CLPRSGHLDNNCA 971
Score = 66.6 bits (161), Expect = 2e-10
Identities = 151/650 (23%), Positives = 213/650 (32%), Gaps = 196/650 (30%)
Query: 76 PGGPGFRAFL----CPLICHNGGVC---VKPDRCLCPPDFAGKFCQLHSSGARPPAPAVP 128
PG G + C C +GG C V +C+CP F G+ C+L
Sbjct: 451 PGWKGINCHINVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSG 510
Query: 129 GLTRSVYTMPLANHRDDEHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARA 188
GL + D H H + SGP E D +
Sbjct: 511 GLCEDL--------ADGFH-------------------CHCPQGFSGPLCEVDVDL---C 540
Query: 189 EAAARAEAAAPYTVLAQSAPREDGYSDASGFGYCFRELRGGECA---SPLPG--LRTQEV 243
E + A Y + E Y A C + G C+ P PG R +
Sbjct: 541 EPSPCRNGARCYNL-------EGDYYCA-----CPDDFGGKNCSVPREPCPGGACRVIDG 588
Query: 244 CCRGAGLAW-GVHDCQLCSERLGNSERVSAPDGP----CPTGFERVNGSC-EDVDECATG 297
C AG G +C + VS P G C +GF C E++D+C G
Sbjct: 589 CGSDAGPGMPGTAASGVCGP---HGRCVSQPGGNFSCICDSGF--TGTYCHENIDDCL-G 642
Query: 298 GRCQHG-ECANTRGGYTCVCPDGF---LLDSSRSSCISQHVISEAKGPCFRVLRDGGCSL 353
C++G C + + C CP G+ L D++ + C+ ++G C+ ++ D C+
Sbjct: 643 QPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDP--CHSRGRCYDLVNDFYCAC 700
Query: 354 P--------ILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDL 405
R CS G + G + FR CP PG+ S +
Sbjct: 701 DDGWKGKTCHSREFQCDAYTCSNGGTCYDSG---------DTFRCACP--PGWKGSTCAV 749
Query: 406 RYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIP 465
N+ L P+P + S
Sbjct: 750 AKNSSCL--------------------------------------PNPCVNGGTCVGSGA 771
Query: 466 AWTGPEIPESGPSSGMCQRNPQVCGP------GRCISRPSGYTCACDSGFRLSPQGTRC- 518
+++ I G C N C P G C+ + + C C GF G C
Sbjct: 772 SFSC--ICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGF----AGPDCR 825
Query: 519 IDVDECRRVPPPCAPG-RCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGR 577
I++DEC+ PCA G C + +RC C PG RAGPR E + GR
Sbjct: 826 INIDECQ--SSPCAYGATCVDEINGYRCSCPPG-RAGPRCQEVI------------GFGR 870
Query: 578 CENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNL------------PG 625
C + PHG+S V++C L GR C + P
Sbjct: 871 S----------CWSRGTPFPHGSSW--VEDCNSCRCLDGRRDCSKVWCGWKPCLLAGQPE 918
Query: 626 SFRCVCPAGFR----------GSACEEDVDECAQEPP--PCGP--GRCDN 661
+ CP G R CE + A+EPP PC P G DN
Sbjct: 919 ALSAQCPLGQRCLEKAPGQCLRPPCEAWGECGAEEPPSTPCLPRSGHLDN 968
Score = 44.7 bits (104), Expect = 7e-04
Identities = 25/78 (32%), Positives = 36/78 (46%), Gaps = 7/78 (8%)
Query: 1464 ELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 1523
ELE +EC + G C + +GF C C G+ + VD++ C+ SP
Sbjct: 496 ELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCE---VDVDLCE----PSPCRNG 548
Query: 1524 ARCLNTDGSFRCICRPGF 1541
ARC N +G + C C F
Sbjct: 549 ARCYNLEGDYYCACPDDF 566
Score = 42.4 bits (98), Expect = 0.004
Identities = 29/90 (32%), Positives = 40/90 (44%), Gaps = 15/90 (16%)
Query: 1449 PEGGSYAGSLAEPYEELEAEECGILDGCTNG-RCVRVPEGFTCRCFDGYRLDMTRMACVD 1507
P+G Y+G E +AE + C NG C VP GF C C G+ +D
Sbjct: 336 PDG--YSGRNCE-----KAEHACTSNPCANGGSCHEVPSGFECHCPSGW---SGPTCALD 385
Query: 1508 INECDEAEAASPLCVNARCLNTDGSFRCIC 1537
I+EC A++P C++ F CIC
Sbjct: 386 IDEC----ASNPCAAGGTCVDQVDGFECIC 411
Score = 38.9 bits (89), Expect = 0.039
Identities = 31/99 (31%), Positives = 38/99 (38%), Gaps = 13/99 (13%)
Query: 29 GERLRVRFTPVVCGLRCVHGPTGSRCTPTCAPRNATSVDSGAPGGAAPGGPGFRAFLC-- 86
G+ R P G C S C P T V SGA G+ C
Sbjct: 731 GDTFRCACPPGWKGSTCAVAKNSS-CLPNPCVNGGTCVGSGASFSCICRD-GWEGRTCTH 788
Query: 87 ------PLICHNGGVCVKP---DRCLCPPDFAGKFCQLH 116
PL C+NGG+CV RC C P FAG C+++
Sbjct: 789 NTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRIN 827
Score = 38.1 bits (87), Expect = 0.067
Identities = 24/78 (30%), Positives = 35/78 (44%), Gaps = 9/78 (11%)
Query: 1465 LEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1524
L+ +EC G CV +GF C C + + + +D NEC+ C+NA
Sbjct: 384 LDIDECASNPCAAGGTCVDQVDGFECICPEQW---VGATCQLDANECEGKP-----CLNA 435
Query: 1525 -RCLNTDGSFRCICRPGF 1541
C N G + C C PG+
Sbjct: 436 FSCKNLIGGYYCDCIPGW 453
Score = 38.1 bits (87), Expect = 0.067
Identities = 23/74 (31%), Positives = 32/74 (43%), Gaps = 7/74 (9%)
Query: 1469 ECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLN 1528
+C L G CV F C C G+ R ++I+EC +SP A C++
Sbjct: 792 DCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCR---INIDECQ----SSPCAYGATCVD 844
Query: 1529 TDGSFRCICRPGFA 1542
+RC C PG A
Sbjct: 845 EINGYRCSCPPGRA 858
Score = 35.4 bits (80), Expect = 0.43
Identities = 27/85 (31%), Positives = 38/85 (44%), Gaps = 18/85 (21%)
Query: 1476 CTNG-RCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPL---CVNA-RCLNTD 1530
C+NG C + F C C G++ + C A+ +S L CVN C+ +
Sbjct: 721 CSNGGTCYDSGDTFRCACPPGWKG----------STCAVAKNSSCLPNPCVNGGTCVGSG 770
Query: 1531 GSFRCICRPGF---APTHQPHHCAP 1552
SF CICR G+ TH + C P
Sbjct: 771 ASFSCICRDGWEGRTCTHNTNDCNP 795
Score = 35.0 bits (79), Expect = 0.57
Identities = 30/115 (26%), Positives = 43/115 (37%), Gaps = 31/115 (26%)
Query: 1461 PYEELEAEECGILDGC------------------TNGRCVRVPEG-FTCRCFDGYRLDMT 1501
P E C ++DGC +GRCV P G F+C C G+ T
Sbjct: 574 PREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGF----T 629
Query: 1502 RMACVD-INECDEAEAASPLCVNARCLNTDGSFRCICRPGFAP---THQPHHCAP 1552
C + I++C P C++ +FRC C G+ P+ C P
Sbjct: 630 GTYCHENIDDC----LGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLP 680
Score = 32.7 bits (73), Expect = 2.8
Identities = 28/88 (31%), Positives = 38/88 (43%), Gaps = 18/88 (20%)
Query: 1476 CTNG-RCVRVPEGFTCRC---FDGYRLDMTRM-----ACVDINECDE-------AEAASP 1519
C NG RC + + C C F G + R AC I+ C AAS
Sbjct: 545 CRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASG 604
Query: 1520 LC-VNARCLNTDG-SFRCICRPGFAPTH 1545
+C + RC++ G +F CIC GF T+
Sbjct: 605 VCGPHGRCVSQPGGNFSCICDSGFTGTY 632
Score = 31.6 bits (70), Expect = 6.3
Identities = 25/95 (26%), Positives = 32/95 (33%), Gaps = 16/95 (16%)
Query: 41 CGLRCVHGPTGSRCTPTCAPRNATSVDSGAPGG--AAPGGPGFRAFLCP--------LIC 90
CG G G+ + C P PGG + GF C C
Sbjct: 589 CGSDAGPGMPGTAASGVCGPHGRCV---SQPGGNFSCICDSGFTGTYCHENIDDCLGQPC 645
Query: 91 HNGGVC---VKPDRCLCPPDFAGKFCQLHSSGARP 122
NGG C V RC CP + G+ C + + P
Sbjct: 646 RNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLP 680
Score = 31.2 bits (69), Expect = 8.2
Identities = 24/94 (25%), Positives = 39/94 (41%), Gaps = 14/94 (14%)
Query: 1468 EECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMAC-VDINECDEAEAASPLCVNARC 1526
+EC GC +G CV E + C C + + C D+N C + P C
Sbjct: 274 DECVPYPGCVHGSCV---EPWQCNC----ETNWGGLLCDKDLNYCG---SHHPCTNGGTC 323
Query: 1527 LNTD-GSFRCICRPGFAPTH--QPHHCAPARPRA 1557
+N + +RC C G++ + + H + P A
Sbjct: 324 INAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCA 357
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 214 bits (546), Expect = 4e-55
Identities = 134/361 (37%), Positives = 171/361 (47%), Gaps = 56/361 (15%)
Query: 547 CGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVD 606
C GF + A C+D DEC P PC C N PG F C CP G+ A +C+DVD
Sbjct: 3428 CPEGFELDSQGAFCVDRDECSGGPSPCSHA-CLNAPGRFSCTCPTGFALAWDDRNCRDVD 3486
Query: 607 ECTQSPGLCGRG-ACKNLPGSFRCV--CPAGFR---GSACEEDVDECAQEPPPCGPGR-C 659
EC LC G C NL GS+RC+ C GFR G+ C EDVDEC + C + C
Sbjct: 3487 ECAWDAHLCREGQRCVNLLGSYRCLPDCGPGFRVADGAGC-EDVDECLEGLDDCHYNQLC 3545
Query: 660 DNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPN 719
+NT G C+CP G+R +GP PC DV+EC + P C Y +C N +GS++C+CP G
Sbjct: 3546 ENTPGGHRCSCPRGYRMQGPSLPCLDVNECLQLPKACAY-QCHNLQGSYRCLCPPGQTLL 3604
Query: 720 TAGSECEDVDECENHLAC-----------------------------PGQECVNSPGSFQ 750
G C ++ ++ PG ++S G
Sbjct: 3605 RDGKACTSLERNGQNVTTVSHRGPLLPWLRPWASIPGTSYHAWVSLRPGPMALSSVGR-- 3662
Query: 751 CRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYR-APSGRPGPC 809
CP G G CTD+DEC H C NTEGS++C C GYR PSG+ C
Sbjct: 3663 -AWCPPGFIRQNGVCTDLDECR--VRNLCQHA-CRNTEGSYQCLCPAGYRLLPSGK--NC 3716
Query: 810 ADVNECLEGDF-CFPHGECLNTDGSFACT---CAPGYRPGPRGASCLDVDECSEEDLCQS 865
D+NEC E C P C NT GS+ C C YR GP +C CS++ C +
Sbjct: 3717 QDINECEEESIECGPGQMCFNTRGSYQCVDTPCPATYRQGPSPGTCF--RRCSQD--CGT 3772
Query: 866 G 866
G
Sbjct: 3773 G 3773
Score = 196 bits (497), Expect = 2e-49
Identities = 122/339 (35%), Positives = 146/339 (43%), Gaps = 76/339 (22%)
Query: 670 CPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVD 729
CP GF GA C D DEC+ P PC++ C N G F C CP GF C DVD
Sbjct: 3428 CPEGFELDSQGAFCVDRDECSGGPSPCSHA-CLNAPGRFSCTCPTGFALAWDDRNCRDVD 3486
Query: 730 EC--ENHLACPGQECVNSPGSFQCRT-CPSGHHLHRGR-CTDVDECSSGAPPCGPHGHCT 785
EC + HL GQ CVN GS++C C G + G C DVDEC G C + C
Sbjct: 3487 ECAWDAHLCREGQRCVNLLGSYRCLPDCGPGFRVADGAGCEDVDECLEGLDDCHYNQLCE 3546
Query: 786 NTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGY--- 842
NT G RCSC GYR G PC DVNECL+ + +C N GS+ C C PG
Sbjct: 3547 NTPGGHRCSCPRGYRM-QGPSLPCLDVNECLQLPKACAY-QCHNLQGSYRCLCPPGQTLL 3604
Query: 843 ----------------------------------------------RPGPRGAS------ 850
RPGP S
Sbjct: 3605 RDGKACTSLERNGQNVTTVSHRGPLLPWLRPWASIPGTSYHAWVSLRPGPMALSSVGRAW 3664
Query: 851 -----------CLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECR 899
C D+DEC +LCQ C NT+GS++C+CP G+R P +C D++EC
Sbjct: 3665 CPPGFIRQNGVCTDLDECRVRNLCQHA-CRNTEGSYQCLCPAGYRLLPSGKNCQDINECE 3723
Query: 900 ERGPALCGSQRCENSPGSYRCV-RDCDPGYHAGPE-GTC 936
E Q C N+ GSY+CV C Y GP GTC
Sbjct: 3724 EESIECGPGQMCFNTRGSYQCVDTPCPATYRQGPSPGTC 3762
Score = 183 bits (464), Expect = 1e-45
Identities = 123/339 (36%), Positives = 157/339 (46%), Gaps = 54/339 (15%)
Query: 482 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPG-RCENSP 540
C P C C++ P ++C C +GF L+ C DVDEC C G RC N
Sbjct: 3447 CSGGPSPCSHA-CLNAPGRFSCTCPTGFALAWDDRNCRDVDECAWDAHLCREGQRCVNLL 3505
Query: 541 GSFRCV--CGPGFRAGPRAAECLDVDECHRVPPPCDLGR-CENTPGSFLCVCPAGYQAAP 597
GS+RC+ CGPGFR A C DVDEC C + CENTPG C CP GY+
Sbjct: 3506 GSYRCLPDCGPGFRVAD-GAGCEDVDECLEGLDDCHYNQLCENTPGGHRCSCPRGYRMQG 3564
Query: 598 HGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFR----GSACE------EDVDEC 647
C DV+EC Q P C C NL GS+RC+CP G G AC ++V
Sbjct: 3565 PSLPCLDVNECLQLPKACAY-QCHNLQGSYRCLCPPGQTLLRDGKACTSLERNGQNVTTV 3623
Query: 648 AQEPP--PCGPGRCDNTAGSFH-----------------CACPAGF-RSRGPGAPCQDVD 687
+ P P S+H CP GF R G C D+D
Sbjct: 3624 SHRGPLLPWLRPWASIPGTSYHAWVSLRPGPMALSSVGRAWCPPGFIRQNG---VCTDLD 3680
Query: 688 ECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENH-LAC-PGQECVNS 745
EC R C + C NTEGS+QC+CP G++ +G C+D++ECE + C PGQ C N+
Sbjct: 3681 EC-RVRNLCQHA-CRNTEGSYQCLCPAGYRLLPSGKNCQDINECEEESIECGPGQMCFNT 3738
Query: 746 PGSFQCRTCPSGHHLHRG--------RCTDVDECSSGAP 776
GS+QC P +G RC+ +C +G P
Sbjct: 3739 RGSYQCVDTPCPATYRQGPSPGTCFRRCS--QDCGTGGP 3775
Score = 181 bits (460), Expect = 4e-45
Identities = 134/368 (36%), Positives = 170/368 (46%), Gaps = 62/368 (16%)
Query: 732 ENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSF 791
EN + CP ++S G+F C D DECS G PC H C N G F
Sbjct: 3423 ENEVGCPEGFELDSQGAF---------------CVDRDECSGGPSPCS-HA-CLNAPGRF 3465
Query: 792 RCSCAPGYRAPSGRPGPCADVNECL-EGDFCFPHGECLNTDGSFACT--CAPGYRPGPRG 848
C+C G+ A + C DV+EC + C C+N GS+ C C PG+R G
Sbjct: 3466 SCTCPTGF-ALAWDDRNCRDVDECAWDAHLCREGQRCVNLLGSYRCLPDCGPGFRVAD-G 3523
Query: 849 ASCLDVDECSE--EDLCQSGICTNTDGSFECICPPGHRA-GPDLASCLDVDECRERGPAL 905
A C DVDEC E +D + +C NT G C CP G+R GP L CLDV+EC + P
Sbjct: 3524 AGCEDVDECLEGLDDCHYNQLCENTPGGHRCSCPRGYRMQGPSLP-CLDVNECLQL-PKA 3581
Query: 906 CGSQRCENSPGSYRCVRDCDPGYHAGPEGTC--------DDVDECQEYGPEICGAQRCEN 957
C Q C N GSYRC+ C PG +G +V GP + + +
Sbjct: 3582 CAYQ-CHNLQGSYRCL--CPPGQTLLRDGKACTSLERNGQNVTTVSHRGPLLPWLRPWAS 3638
Query: 958 TPG-------SYRCTPA---------CDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNL 1001
PG S R P C PG+ G C D+DECR R+ C HA C+N
Sbjct: 3639 IPGTSYHAWVSLRPGPMALSSVGRAWCPPGFI-RQNGVCTDLDECRVRNLC-QHA-CRNT 3695
Query: 1002 PGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCG-AALCENVEGSFLCV---CPNSPEE 1057
GS+QCLC GY G++C D+NECE CG +C N GS+ CV CP + +
Sbjct: 3696 EGSYQCLCPAGYRLLPSGKNCQDINECEEESIECGPGQMCFNTRGSYQCVDTPCPATYRQ 3755
Query: 1058 FDPMTGRC 1065
P G C
Sbjct: 3756 -GPSPGTC 3762
Score = 174 bits (440), Expect = 8e-43
Identities = 121/344 (35%), Positives = 151/344 (43%), Gaps = 48/344 (13%)
Query: 505 CDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVD 564
C GF L QG C+D DEC P PC+ C N+PG F C C GF C DVD
Sbjct: 3428 CPEGFELDSQGAFCVDRDECSGGPSPCSHA-CLNAPGRFSCTCPTGFALAWDDRNCRDVD 3486
Query: 565 ECHRVPPPCDLG-RCENTPGSFLCV--CPAGYQAAPHGASCQDVDECTQSPGLCG-RGAC 620
EC C G RC N GS+ C+ C G++ A GA C+DVDEC + C C
Sbjct: 3487 ECAWDAHLCREGQRCVNLLGSYRCLPDCGPGFRVA-DGAGCEDVDECLEGLDDCHYNQLC 3545
Query: 621 KNLPGSFRCVCPAGFR---GSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSR 677
+N PG RC CP G+R S DV+EC Q P C +C N GS+ C CP G
Sbjct: 3546 ENTPGGHRCSCPRGYRMQGPSLPCLDVNECLQLPKACA-YQCHNLQGSYRCLCPPGQTLL 3604
Query: 678 GPGAPCQDVDECAR-------------------SPPPCTYGRCENTEGSFQCV------- 711
G C ++ + S P +Y + +
Sbjct: 3605 RDGKACTSLERNGQNVTTVSHRGPLLPWLRPWASIPGTSYHAWVSLRPGPMALSSVGRAW 3664
Query: 712 CPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHL--HRGRCTDVD 769
CP GF C D+DEC C C N+ GS+QC CP+G+ L C D++
Sbjct: 3665 CPPGF--IRQNGVCTDLDECRVRNLCQ-HACRNTEGSYQC-LCPAGYRLLPSGKNCQDIN 3720
Query: 770 ECSSGAPPCGPHGHCTNTEGSFRC---SCAPGYR-APSGRPGPC 809
EC + CGP C NT GS++C C YR PS PG C
Sbjct: 3721 ECEEESIECGPGQMCFNTRGSYQCVDTPCPATYRQGPS--PGTC 3762
Score = 102 bits (255), Expect = 2e-21
Identities = 106/358 (29%), Positives = 146/358 (40%), Gaps = 60/358 (16%)
Query: 924 CDPGYHAGPEGT-CDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPT-PGGGCQ 981
C G+ +G C D DEC GP C + C N PG + CT C G+ C+
Sbjct: 3428 CPEGFELDSQGAFCVDRDECSG-GPSPC-SHACLNAPGRFSCT--CPTGFALAWDDRNCR 3483
Query: 982 DVDECR-NRSFCGAHAVCQNLPGSFQCL--CDQGYEGARDGRHCVDVNEC-ETLQGVCGA 1037
DVDEC + C C NL GS++CL C G+ A DG C DV+EC E L
Sbjct: 3484 DVDECAWDAHLCREGQRCVNLLGSYRCLPDCGPGFRVA-DGAGCEDVDECLEGLDDCHYN 3542
Query: 1038 ALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPL 1097
LCEN G C CP G + Q P+ P L L
Sbjct: 3543 QLCENTPGGHRCSCPR-----------------------GYRMQGPSLPCLDVNECLQ-L 3578
Query: 1098 PRRPSTPRQGPVGSGRRECY-FDTAAPD--ACDNIL--ARNVT----------WQECCCT 1142
P+ + GS R C T D AC ++ +NVT W +
Sbjct: 3579 PKACAYQCHNLQGSYRCLCPPGQTLLRDGKACTSLERNGQNVTTVSHRGPLLPWLRPWAS 3638
Query: 1143 V-GEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSG 1201
+ G + + ++ P ++ ++ CP G ++ +G + D+DEC++ +C+
Sbjct: 3639 IPGTSYHAWVSLRPGPMALSSVGRAWCPPG--FIRQNGVCT---DLDECRV--RNLCQHA 3691
Query: 1202 VCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGR-CVNTVGSYHCTCEP 1258
C NT Y C C GY C D +EC +E C G+ C NT GSY C P
Sbjct: 3692 -CRNTEGSYQCLCPAGYRLLPSGKNCQDINECEEESIECGPGQMCFNTRGSYQCVDTP 3748
Score = 89.7 bits (221), Expect = 2e-17
Identities = 85/323 (26%), Positives = 124/323 (38%), Gaps = 62/323 (19%)
Query: 251 AWGVHDC---QLCSERLGNSERVSAPDGPCPTGFERVNGS-CEDVDECATG-GRCQHGE- 304
AW H C Q C LG+ + PD C GF +G+ CEDVDEC G C + +
Sbjct: 3489 AWDAHLCREGQRCVNLLGSYRCL--PD--CGPGFRVADGAGCEDVDECLEGLDDCHYNQL 3544
Query: 305 CANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQIC 364
C NT GG+ C CP G+ + C+ + + C N+
Sbjct: 3545 CENTPGGHRCSCPRGYRMQGPSLPCLDVNECLQLPKACAYQ----------CHNLQGSYR 3594
Query: 365 CCSRVGKAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQP 424
C G+ R + C G N + P + +P
Sbjct: 3595 CLCPPGQTLLRDGKACTSLERNG-------------------QNVTTVSHRGPLLPWLRP 3635
Query: 425 -RTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSI-PAWTGPE-IPESGPSSGM 481
++P TS + L RPGP + L S+ AW P I ++G + +
Sbjct: 3636 WASIPGTSYHAWVSL---------------RPGP-MALSSVGRAWCPPGFIRQNGVCTDL 3679
Query: 482 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGR-CENSP 540
+ + C + Y C C +G+RL P G C D++EC C PG+ C N+
Sbjct: 3680 DECRVRNLCQHACRNTEGSYQCLCPAGYRLLPSGKNCQDINECEEESIECGPGQMCFNTR 3739
Query: 541 GSFRCV---CGPGFRAGPRAAEC 560
GS++CV C +R GP C
Sbjct: 3740 GSYQCVDTPCPATYRQGPSPGTC 3762
Score = 63.2 bits (152), Expect = 2e-09
Identities = 51/165 (30%), Positives = 64/165 (38%), Gaps = 16/165 (9%)
Query: 1112 GRRECYFDTAAPDACDNILARNV---TWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLC 1168
GR C T A D+ R+V W C G Q+C Y+ L
Sbjct: 3463 GRFSCTCPTGFALAWDDRNCRDVDECAWDAHLCREG---------QRCVNL-LGSYRCLP 3512
Query: 1169 PHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECI 1228
G G+ G + DVDEC D + +C NT G+ C C GY L C+
Sbjct: 3513 DCGPGFRVADG--AGCEDVDECLEGLDDCHYNQLCENTPGGHRCSCPRGYRMQGPSLPCL 3570
Query: 1229 DNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNE 1273
D +EC AC +C N GSY C C P L + C S E
Sbjct: 3571 DVNECLQLPKAC-AYQCHNLQGSYRCLCPPGQTLLRDGKACTSLE 3614
Score = 56.2 bits (134), Expect = 2e-07
Identities = 28/77 (36%), Positives = 39/77 (50%), Gaps = 6/77 (7%)
Query: 1466 EAEEC--GILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 1523
+ +EC G+ D N C P G C C GYR+ + C+D+NEC + P
Sbjct: 3528 DVDECLEGLDDCHYNQLCENTPGGHRCSCPRGYRMQGPSLPCLDVNECLQL----PKACA 3583
Query: 1524 ARCLNTDGSFRCICRPG 1540
+C N GS+RC+C PG
Sbjct: 3584 YQCHNLQGSYRCLCPPG 3600
Score = 54.3 bits (129), Expect = 9e-07
Identities = 46/132 (34%), Positives = 56/132 (42%), Gaps = 9/132 (6%)
Query: 1152 RIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYS 1211
R Q + E + CP G L G + RD EC C S C+N +S
Sbjct: 3412 RFQLATALQAEENEVGCPEGFE-LDSQGAFCVDRD--ECS-GGPSPC-SHACLNAPGRFS 3466
Query: 1212 CYCSNGYYYHTQRLECIDNDECADEEPAC-EGGRCVNTVGSYHC--TCEPPL-VLDGSQR 1267
C C G+ C D DECA + C EG RCVN +GSY C C P V DG+
Sbjct: 3467 CTCPTGFALAWDDRNCRDVDECAWDAHLCREGQRCVNLLGSYRCLPDCGPGFRVADGAGC 3526
Query: 1268 RCVSNESQSLDD 1279
V + LDD
Sbjct: 3527 EDVDECLEGLDD 3538
Score = 45.1 bits (105), Expect = 5e-04
Identities = 28/80 (35%), Positives = 37/80 (46%), Gaps = 10/80 (12%)
Query: 1470 CGILDGCTNG------RCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 1523
C D C+ G C+ P F+C C G+ L C D++EC A A
Sbjct: 3441 CVDRDECSGGPSPCSHACLNAPGRFSCTCPTGFALAWDDRNCRDVDEC--AWDAHLCREG 3498
Query: 1524 ARCLNTDGSFRCI--CRPGF 1541
RC+N GS+RC+ C PGF
Sbjct: 3499 QRCVNLLGSYRCLPDCGPGF 3518
Score = 45.1 bits (105), Expect = 5e-04
Identities = 24/74 (32%), Positives = 35/74 (47%), Gaps = 3/74 (4%)
Query: 1466 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNAR 1525
+ +EC + + C + C + C C GYRL + C DINEC+E
Sbjct: 3678 DLDECRVRNLCQHA-CRNTEGSYQCLCPAGYRLLPSGKNCQDINECEEESIECG--PGQM 3734
Query: 1526 CLNTDGSFRCICRP 1539
C NT GS++C+ P
Sbjct: 3735 CFNTRGSYQCVDTP 3748
Score = 42.0 bits (97), Expect = 0.005
Identities = 21/59 (35%), Positives = 27/59 (45%), Gaps = 4/59 (6%)
Query: 1492 CFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHC 1550
C +G+ LD CVD +EC + P + CLN G F C C GFA +C
Sbjct: 3428 CPEGFELDSQGAFCVDRDEC----SGGPSPCSHACLNAPGRFSCTCPTGFALAWDDRNC 3482
Score = 41.6 bits (96), Expect = 0.006
Identities = 20/68 (29%), Positives = 29/68 (42%), Gaps = 1/68 (1%)
Query: 1214 CSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNE 1273
C G+ +Q C+D DEC+ C C+N G + CTC L R C +
Sbjct: 3428 CPEGFELDSQGAFCVDRDECSGGPSPCSHA-CLNAPGRFSCTCPTGFALAWDDRNCRDVD 3486
Query: 1274 SQSLDDNL 1281
+ D +L
Sbjct: 3487 ECAWDAHL 3494
Score = 35.4 bits (80), Expect = 0.43
Identities = 23/69 (33%), Positives = 30/69 (43%), Gaps = 6/69 (8%)
Query: 1476 CTNG-RCVRVPEGFTCR--CFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGS 1532
C G RCV + + C C G+R+ C D++EC E N C NT G
Sbjct: 3495 CREGQRCVNLLGSYRCLPDCGPGFRV-ADGAGCEDVDEC--LEGLDDCHYNQLCENTPGG 3551
Query: 1533 FRCICRPGF 1541
RC C G+
Sbjct: 3552 HRCSCPRGY 3560
Score = 34.3 bits (77), Expect = 0.96
Identities = 15/37 (40%), Positives = 23/37 (62%), Gaps = 5/37 (13%)
Query: 1505 CVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGF 1541
C D++EC LC +A C NT+GS++C+C G+
Sbjct: 3676 CTDLDEC----RVRNLCQHA-CRNTEGSYQCLCPAGY 3707
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 214 bits (546), Expect = 4e-55
Identities = 134/361 (37%), Positives = 171/361 (47%), Gaps = 56/361 (15%)
Query: 547 CGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVD 606
C GF + A C+D DEC P PC C N PG F C CP G+ A +C+DVD
Sbjct: 4619 CPEGFELDSQGAFCVDRDECSGGPSPCSHA-CLNAPGRFSCTCPTGFALAWDDRNCRDVD 4677
Query: 607 ECTQSPGLCGRG-ACKNLPGSFRCV--CPAGFR---GSACEEDVDECAQEPPPCGPGR-C 659
EC LC G C NL GS+RC+ C GFR G+ C EDVDEC + C + C
Sbjct: 4678 ECAWDAHLCREGQRCVNLLGSYRCLPDCGPGFRVADGAGC-EDVDECLEGLDDCHYNQLC 4736
Query: 660 DNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPN 719
+NT G C+CP G+R +GP PC DV+EC + P C Y +C N +GS++C+CP G
Sbjct: 4737 ENTPGGHRCSCPRGYRMQGPSLPCLDVNECLQLPKACAY-QCHNLQGSYRCLCPPGQTLL 4795
Query: 720 TAGSECEDVDECENHLAC-----------------------------PGQECVNSPGSFQ 750
G C ++ ++ PG ++S G
Sbjct: 4796 RDGKACTSLERNGQNVTTVSHRGPLLPWLRPWASIPGTSYHAWVSLRPGPMALSSVGR-- 4853
Query: 751 CRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYR-APSGRPGPC 809
CP G G CTD+DEC H C NTEGS++C C GYR PSG+ C
Sbjct: 4854 -AWCPPGFIRQNGVCTDLDECR--VRNLCQHA-CRNTEGSYQCLCPAGYRLLPSGK--NC 4907
Query: 810 ADVNECLEGDF-CFPHGECLNTDGSFACT---CAPGYRPGPRGASCLDVDECSEEDLCQS 865
D+NEC E C P C NT GS+ C C YR GP +C CS++ C +
Sbjct: 4908 QDINECEEESIECGPGQMCFNTRGSYQCVDTPCPATYRQGPSPGTCF--RRCSQD--CGT 4963
Query: 866 G 866
G
Sbjct: 4964 G 4964
Score = 196 bits (497), Expect = 2e-49
Identities = 122/339 (35%), Positives = 146/339 (43%), Gaps = 76/339 (22%)
Query: 670 CPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVD 729
CP GF GA C D DEC+ P PC++ C N G F C CP GF C DVD
Sbjct: 4619 CPEGFELDSQGAFCVDRDECSGGPSPCSHA-CLNAPGRFSCTCPTGFALAWDDRNCRDVD 4677
Query: 730 EC--ENHLACPGQECVNSPGSFQCRT-CPSGHHLHRGR-CTDVDECSSGAPPCGPHGHCT 785
EC + HL GQ CVN GS++C C G + G C DVDEC G C + C
Sbjct: 4678 ECAWDAHLCREGQRCVNLLGSYRCLPDCGPGFRVADGAGCEDVDECLEGLDDCHYNQLCE 4737
Query: 786 NTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGY--- 842
NT G RCSC GYR G PC DVNECL+ + +C N GS+ C C PG
Sbjct: 4738 NTPGGHRCSCPRGYRM-QGPSLPCLDVNECLQLPKACAY-QCHNLQGSYRCLCPPGQTLL 4795
Query: 843 ----------------------------------------------RPGPRGAS------ 850
RPGP S
Sbjct: 4796 RDGKACTSLERNGQNVTTVSHRGPLLPWLRPWASIPGTSYHAWVSLRPGPMALSSVGRAW 4855
Query: 851 -----------CLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECR 899
C D+DEC +LCQ C NT+GS++C+CP G+R P +C D++EC
Sbjct: 4856 CPPGFIRQNGVCTDLDECRVRNLCQHA-CRNTEGSYQCLCPAGYRLLPSGKNCQDINECE 4914
Query: 900 ERGPALCGSQRCENSPGSYRCV-RDCDPGYHAGPE-GTC 936
E Q C N+ GSY+CV C Y GP GTC
Sbjct: 4915 EESIECGPGQMCFNTRGSYQCVDTPCPATYRQGPSPGTC 4953
Score = 183 bits (464), Expect = 1e-45
Identities = 123/339 (36%), Positives = 157/339 (46%), Gaps = 54/339 (15%)
Query: 482 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPG-RCENSP 540
C P C C++ P ++C C +GF L+ C DVDEC C G RC N
Sbjct: 4638 CSGGPSPCSHA-CLNAPGRFSCTCPTGFALAWDDRNCRDVDECAWDAHLCREGQRCVNLL 4696
Query: 541 GSFRCV--CGPGFRAGPRAAECLDVDECHRVPPPCDLGR-CENTPGSFLCVCPAGYQAAP 597
GS+RC+ CGPGFR A C DVDEC C + CENTPG C CP GY+
Sbjct: 4697 GSYRCLPDCGPGFRVAD-GAGCEDVDECLEGLDDCHYNQLCENTPGGHRCSCPRGYRMQG 4755
Query: 598 HGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFR----GSACE------EDVDEC 647
C DV+EC Q P C C NL GS+RC+CP G G AC ++V
Sbjct: 4756 PSLPCLDVNECLQLPKACAY-QCHNLQGSYRCLCPPGQTLLRDGKACTSLERNGQNVTTV 4814
Query: 648 AQEPP--PCGPGRCDNTAGSFH-----------------CACPAGF-RSRGPGAPCQDVD 687
+ P P S+H CP GF R G C D+D
Sbjct: 4815 SHRGPLLPWLRPWASIPGTSYHAWVSLRPGPMALSSVGRAWCPPGFIRQNG---VCTDLD 4871
Query: 688 ECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENH-LAC-PGQECVNS 745
EC R C + C NTEGS+QC+CP G++ +G C+D++ECE + C PGQ C N+
Sbjct: 4872 EC-RVRNLCQHA-CRNTEGSYQCLCPAGYRLLPSGKNCQDINECEEESIECGPGQMCFNT 4929
Query: 746 PGSFQCRTCPSGHHLHRG--------RCTDVDECSSGAP 776
GS+QC P +G RC+ +C +G P
Sbjct: 4930 RGSYQCVDTPCPATYRQGPSPGTCFRRCS--QDCGTGGP 4966
Score = 181 bits (460), Expect = 4e-45
Identities = 134/368 (36%), Positives = 170/368 (46%), Gaps = 62/368 (16%)
Query: 732 ENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSF 791
EN + CP ++S G+F C D DECS G PC H C N G F
Sbjct: 4614 ENEVGCPEGFELDSQGAF---------------CVDRDECSGGPSPCS-HA-CLNAPGRF 4656
Query: 792 RCSCAPGYRAPSGRPGPCADVNECL-EGDFCFPHGECLNTDGSFACT--CAPGYRPGPRG 848
C+C G+ A + C DV+EC + C C+N GS+ C C PG+R G
Sbjct: 4657 SCTCPTGF-ALAWDDRNCRDVDECAWDAHLCREGQRCVNLLGSYRCLPDCGPGFRVAD-G 4714
Query: 849 ASCLDVDECSE--EDLCQSGICTNTDGSFECICPPGHRA-GPDLASCLDVDECRERGPAL 905
A C DVDEC E +D + +C NT G C CP G+R GP L CLDV+EC + P
Sbjct: 4715 AGCEDVDECLEGLDDCHYNQLCENTPGGHRCSCPRGYRMQGPSLP-CLDVNECLQL-PKA 4772
Query: 906 CGSQRCENSPGSYRCVRDCDPGYHAGPEGTC--------DDVDECQEYGPEICGAQRCEN 957
C Q C N GSYRC+ C PG +G +V GP + + +
Sbjct: 4773 CAYQ-CHNLQGSYRCL--CPPGQTLLRDGKACTSLERNGQNVTTVSHRGPLLPWLRPWAS 4829
Query: 958 TPG-------SYRCTPA---------CDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNL 1001
PG S R P C PG+ G C D+DECR R+ C HA C+N
Sbjct: 4830 IPGTSYHAWVSLRPGPMALSSVGRAWCPPGFI-RQNGVCTDLDECRVRNLC-QHA-CRNT 4886
Query: 1002 PGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCG-AALCENVEGSFLCV---CPNSPEE 1057
GS+QCLC GY G++C D+NECE CG +C N GS+ CV CP + +
Sbjct: 4887 EGSYQCLCPAGYRLLPSGKNCQDINECEEESIECGPGQMCFNTRGSYQCVDTPCPATYRQ 4946
Query: 1058 FDPMTGRC 1065
P G C
Sbjct: 4947 -GPSPGTC 4953
Score = 174 bits (440), Expect = 8e-43
Identities = 121/344 (35%), Positives = 151/344 (43%), Gaps = 48/344 (13%)
Query: 505 CDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVD 564
C GF L QG C+D DEC P PC+ C N+PG F C C GF C DVD
Sbjct: 4619 CPEGFELDSQGAFCVDRDECSGGPSPCSHA-CLNAPGRFSCTCPTGFALAWDDRNCRDVD 4677
Query: 565 ECHRVPPPCDLG-RCENTPGSFLCV--CPAGYQAAPHGASCQDVDECTQSPGLCG-RGAC 620
EC C G RC N GS+ C+ C G++ A GA C+DVDEC + C C
Sbjct: 4678 ECAWDAHLCREGQRCVNLLGSYRCLPDCGPGFRVA-DGAGCEDVDECLEGLDDCHYNQLC 4736
Query: 621 KNLPGSFRCVCPAGFR---GSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSR 677
+N PG RC CP G+R S DV+EC Q P C +C N GS+ C CP G
Sbjct: 4737 ENTPGGHRCSCPRGYRMQGPSLPCLDVNECLQLPKACA-YQCHNLQGSYRCLCPPGQTLL 4795
Query: 678 GPGAPCQDVDECAR-------------------SPPPCTYGRCENTEGSFQCV------- 711
G C ++ + S P +Y + +
Sbjct: 4796 RDGKACTSLERNGQNVTTVSHRGPLLPWLRPWASIPGTSYHAWVSLRPGPMALSSVGRAW 4855
Query: 712 CPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHL--HRGRCTDVD 769
CP GF C D+DEC C C N+ GS+QC CP+G+ L C D++
Sbjct: 4856 CPPGF--IRQNGVCTDLDECRVRNLCQ-HACRNTEGSYQC-LCPAGYRLLPSGKNCQDIN 4911
Query: 770 ECSSGAPPCGPHGHCTNTEGSFRC---SCAPGYR-APSGRPGPC 809
EC + CGP C NT GS++C C YR PS PG C
Sbjct: 4912 ECEEESIECGPGQMCFNTRGSYQCVDTPCPATYRQGPS--PGTC 4953
Score = 102 bits (255), Expect = 2e-21
Identities = 106/358 (29%), Positives = 146/358 (40%), Gaps = 60/358 (16%)
Query: 924 CDPGYHAGPEGT-CDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPT-PGGGCQ 981
C G+ +G C D DEC GP C + C N PG + CT C G+ C+
Sbjct: 4619 CPEGFELDSQGAFCVDRDECSG-GPSPC-SHACLNAPGRFSCT--CPTGFALAWDDRNCR 4674
Query: 982 DVDECR-NRSFCGAHAVCQNLPGSFQCL--CDQGYEGARDGRHCVDVNEC-ETLQGVCGA 1037
DVDEC + C C NL GS++CL C G+ A DG C DV+EC E L
Sbjct: 4675 DVDECAWDAHLCREGQRCVNLLGSYRCLPDCGPGFRVA-DGAGCEDVDECLEGLDDCHYN 4733
Query: 1038 ALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPL 1097
LCEN G C CP G + Q P+ P L L
Sbjct: 4734 QLCENTPGGHRCSCPR-----------------------GYRMQGPSLPCLDVNECLQ-L 4769
Query: 1098 PRRPSTPRQGPVGSGRRECY-FDTAAPD--ACDNIL--ARNVT----------WQECCCT 1142
P+ + GS R C T D AC ++ +NVT W +
Sbjct: 4770 PKACAYQCHNLQGSYRCLCPPGQTLLRDGKACTSLERNGQNVTTVSHRGPLLPWLRPWAS 4829
Query: 1143 V-GEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSG 1201
+ G + + ++ P ++ ++ CP G ++ +G + D+DEC++ +C+
Sbjct: 4830 IPGTSYHAWVSLRPGPMALSSVGRAWCPPG--FIRQNGVCT---DLDECRV--RNLCQHA 4882
Query: 1202 VCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGR-CVNTVGSYHCTCEP 1258
C NT Y C C GY C D +EC +E C G+ C NT GSY C P
Sbjct: 4883 -CRNTEGSYQCLCPAGYRLLPSGKNCQDINECEEESIECGPGQMCFNTRGSYQCVDTP 4939
Score = 89.7 bits (221), Expect = 2e-17
Identities = 85/323 (26%), Positives = 124/323 (38%), Gaps = 62/323 (19%)
Query: 251 AWGVHDC---QLCSERLGNSERVSAPDGPCPTGFERVNGS-CEDVDECATG-GRCQHGE- 304
AW H C Q C LG+ + PD C GF +G+ CEDVDEC G C + +
Sbjct: 4680 AWDAHLCREGQRCVNLLGSYRCL--PD--CGPGFRVADGAGCEDVDECLEGLDDCHYNQL 4735
Query: 305 CANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQIC 364
C NT GG+ C CP G+ + C+ + + C N+
Sbjct: 4736 CENTPGGHRCSCPRGYRMQGPSLPCLDVNECLQLPKACAYQ----------CHNLQGSYR 4785
Query: 365 CCSRVGKAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQP 424
C G+ R + C G N + P + +P
Sbjct: 4786 CLCPPGQTLLRDGKACTSLERNG-------------------QNVTTVSHRGPLLPWLRP 4826
Query: 425 -RTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSI-PAWTGPE-IPESGPSSGM 481
++P TS + L RPGP + L S+ AW P I ++G + +
Sbjct: 4827 WASIPGTSYHAWVSL---------------RPGP-MALSSVGRAWCPPGFIRQNGVCTDL 4870
Query: 482 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGR-CENSP 540
+ + C + Y C C +G+RL P G C D++EC C PG+ C N+
Sbjct: 4871 DECRVRNLCQHACRNTEGSYQCLCPAGYRLLPSGKNCQDINECEEESIECGPGQMCFNTR 4930
Query: 541 GSFRCV---CGPGFRAGPRAAEC 560
GS++CV C +R GP C
Sbjct: 4931 GSYQCVDTPCPATYRQGPSPGTC 4953
Score = 63.2 bits (152), Expect = 2e-09
Identities = 51/165 (30%), Positives = 64/165 (38%), Gaps = 16/165 (9%)
Query: 1112 GRRECYFDTAAPDACDNILARNV---TWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLC 1168
GR C T A D+ R+V W C G Q+C Y+ L
Sbjct: 4654 GRFSCTCPTGFALAWDDRNCRDVDECAWDAHLCREG---------QRCVNL-LGSYRCLP 4703
Query: 1169 PHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECI 1228
G G+ G + DVDEC D + +C NT G+ C C GY L C+
Sbjct: 4704 DCGPGFRVADG--AGCEDVDECLEGLDDCHYNQLCENTPGGHRCSCPRGYRMQGPSLPCL 4761
Query: 1229 DNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNE 1273
D +EC AC +C N GSY C C P L + C S E
Sbjct: 4762 DVNECLQLPKAC-AYQCHNLQGSYRCLCPPGQTLLRDGKACTSLE 4805
Score = 56.2 bits (134), Expect = 2e-07
Identities = 28/77 (36%), Positives = 39/77 (50%), Gaps = 6/77 (7%)
Query: 1466 EAEEC--GILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 1523
+ +EC G+ D N C P G C C GYR+ + C+D+NEC + P
Sbjct: 4719 DVDECLEGLDDCHYNQLCENTPGGHRCSCPRGYRMQGPSLPCLDVNECLQL----PKACA 4774
Query: 1524 ARCLNTDGSFRCICRPG 1540
+C N GS+RC+C PG
Sbjct: 4775 YQCHNLQGSYRCLCPPG 4791
Score = 54.3 bits (129), Expect = 9e-07
Identities = 46/132 (34%), Positives = 56/132 (42%), Gaps = 9/132 (6%)
Query: 1152 RIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYS 1211
R Q + E + CP G L G + RD EC C S C+N +S
Sbjct: 4603 RFQLATALQAEENEVGCPEGFE-LDSQGAFCVDRD--ECS-GGPSPC-SHACLNAPGRFS 4657
Query: 1212 CYCSNGYYYHTQRLECIDNDECADEEPAC-EGGRCVNTVGSYHC--TCEPPL-VLDGSQR 1267
C C G+ C D DECA + C EG RCVN +GSY C C P V DG+
Sbjct: 4658 CTCPTGFALAWDDRNCRDVDECAWDAHLCREGQRCVNLLGSYRCLPDCGPGFRVADGAGC 4717
Query: 1268 RCVSNESQSLDD 1279
V + LDD
Sbjct: 4718 EDVDECLEGLDD 4729
Score = 45.1 bits (105), Expect = 5e-04
Identities = 28/80 (35%), Positives = 37/80 (46%), Gaps = 10/80 (12%)
Query: 1470 CGILDGCTNG------RCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 1523
C D C+ G C+ P F+C C G+ L C D++EC A A
Sbjct: 4632 CVDRDECSGGPSPCSHACLNAPGRFSCTCPTGFALAWDDRNCRDVDEC--AWDAHLCREG 4689
Query: 1524 ARCLNTDGSFRCI--CRPGF 1541
RC+N GS+RC+ C PGF
Sbjct: 4690 QRCVNLLGSYRCLPDCGPGF 4709
Score = 45.1 bits (105), Expect = 5e-04
Identities = 24/74 (32%), Positives = 35/74 (47%), Gaps = 3/74 (4%)
Query: 1466 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNAR 1525
+ +EC + + C + C + C C GYRL + C DINEC+E
Sbjct: 4869 DLDECRVRNLCQHA-CRNTEGSYQCLCPAGYRLLPSGKNCQDINECEEESIECG--PGQM 4925
Query: 1526 CLNTDGSFRCICRP 1539
C NT GS++C+ P
Sbjct: 4926 CFNTRGSYQCVDTP 4939
Score = 42.0 bits (97), Expect = 0.005
Identities = 21/59 (35%), Positives = 27/59 (45%), Gaps = 4/59 (6%)
Query: 1492 CFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHC 1550
C +G+ LD CVD +EC + P + CLN G F C C GFA +C
Sbjct: 4619 CPEGFELDSQGAFCVDRDEC----SGGPSPCSHACLNAPGRFSCTCPTGFALAWDDRNC 4673
Score = 41.6 bits (96), Expect = 0.006
Identities = 20/68 (29%), Positives = 29/68 (42%), Gaps = 1/68 (1%)
Query: 1214 CSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNE 1273
C G+ +Q C+D DEC+ C C+N G + CTC L R C +
Sbjct: 4619 CPEGFELDSQGAFCVDRDECSGGPSPCSHA-CLNAPGRFSCTCPTGFALAWDDRNCRDVD 4677
Query: 1274 SQSLDDNL 1281
+ D +L
Sbjct: 4678 ECAWDAHL 4685
Score = 35.4 bits (80), Expect = 0.43
Identities = 23/69 (33%), Positives = 30/69 (43%), Gaps = 6/69 (8%)
Query: 1476 CTNG-RCVRVPEGFTCR--CFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGS 1532
C G RCV + + C C G+R+ C D++EC E N C NT G
Sbjct: 4686 CREGQRCVNLLGSYRCLPDCGPGFRV-ADGAGCEDVDEC--LEGLDDCHYNQLCENTPGG 4742
Query: 1533 FRCICRPGF 1541
RC C G+
Sbjct: 4743 HRCSCPRGY 4751
Score = 34.3 bits (77), Expect = 0.96
Identities = 15/37 (40%), Positives = 23/37 (62%), Gaps = 5/37 (13%)
Query: 1505 CVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGF 1541
C D++EC LC +A C NT+GS++C+C G+
Sbjct: 4867 CTDLDEC----RVRNLCQHA-CRNTEGSYQCLCPAGY 4898
>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3783
Score = 214 bits (546), Expect = 4e-55
Identities = 134/361 (37%), Positives = 171/361 (47%), Gaps = 56/361 (15%)
Query: 547 CGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVD 606
C GF + A C+D DEC P PC C N PG F C CP G+ A +C+DVD
Sbjct: 3337 CPEGFELDSQGAFCVDRDECSGGPSPCSHA-CLNAPGRFSCTCPTGFALAWDDRNCRDVD 3395
Query: 607 ECTQSPGLCGRG-ACKNLPGSFRCV--CPAGFR---GSACEEDVDECAQEPPPCGPGR-C 659
EC LC G C NL GS+RC+ C GFR G+ C EDVDEC + C + C
Sbjct: 3396 ECAWDAHLCREGQRCVNLLGSYRCLPDCGPGFRVADGAGC-EDVDECLEGLDDCHYNQLC 3454
Query: 660 DNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPN 719
+NT G C+CP G+R +GP PC DV+EC + P C Y +C N +GS++C+CP G
Sbjct: 3455 ENTPGGHRCSCPRGYRMQGPSLPCLDVNECLQLPKACAY-QCHNLQGSYRCLCPPGQTLL 3513
Query: 720 TAGSECEDVDECENHLAC-----------------------------PGQECVNSPGSFQ 750
G C ++ ++ PG ++S G
Sbjct: 3514 RDGKACTSLERNGQNVTTVSHRGPLLPWLRPWASIPGTSYHAWVSLRPGPMALSSVGR-- 3571
Query: 751 CRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYR-APSGRPGPC 809
CP G G CTD+DEC H C NTEGS++C C GYR PSG+ C
Sbjct: 3572 -AWCPPGFIRQNGVCTDLDECR--VRNLCQHA-CRNTEGSYQCLCPAGYRLLPSGK--NC 3625
Query: 810 ADVNECLEGDF-CFPHGECLNTDGSFACT---CAPGYRPGPRGASCLDVDECSEEDLCQS 865
D+NEC E C P C NT GS+ C C YR GP +C CS++ C +
Sbjct: 3626 QDINECEEESIECGPGQMCFNTRGSYQCVDTPCPATYRQGPSPGTCF--RRCSQD--CGT 3681
Query: 866 G 866
G
Sbjct: 3682 G 3682
Score = 196 bits (497), Expect = 2e-49
Identities = 122/339 (35%), Positives = 146/339 (43%), Gaps = 76/339 (22%)
Query: 670 CPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVD 729
CP GF GA C D DEC+ P PC++ C N G F C CP GF C DVD
Sbjct: 3337 CPEGFELDSQGAFCVDRDECSGGPSPCSHA-CLNAPGRFSCTCPTGFALAWDDRNCRDVD 3395
Query: 730 EC--ENHLACPGQECVNSPGSFQCRT-CPSGHHLHRGR-CTDVDECSSGAPPCGPHGHCT 785
EC + HL GQ CVN GS++C C G + G C DVDEC G C + C
Sbjct: 3396 ECAWDAHLCREGQRCVNLLGSYRCLPDCGPGFRVADGAGCEDVDECLEGLDDCHYNQLCE 3455
Query: 786 NTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGY--- 842
NT G RCSC GYR G PC DVNECL+ + +C N GS+ C C PG
Sbjct: 3456 NTPGGHRCSCPRGYRM-QGPSLPCLDVNECLQLPKACAY-QCHNLQGSYRCLCPPGQTLL 3513
Query: 843 ----------------------------------------------RPGPRGAS------ 850
RPGP S
Sbjct: 3514 RDGKACTSLERNGQNVTTVSHRGPLLPWLRPWASIPGTSYHAWVSLRPGPMALSSVGRAW 3573
Query: 851 -----------CLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECR 899
C D+DEC +LCQ C NT+GS++C+CP G+R P +C D++EC
Sbjct: 3574 CPPGFIRQNGVCTDLDECRVRNLCQHA-CRNTEGSYQCLCPAGYRLLPSGKNCQDINECE 3632
Query: 900 ERGPALCGSQRCENSPGSYRCV-RDCDPGYHAGPE-GTC 936
E Q C N+ GSY+CV C Y GP GTC
Sbjct: 3633 EESIECGPGQMCFNTRGSYQCVDTPCPATYRQGPSPGTC 3671
Score = 183 bits (464), Expect = 1e-45
Identities = 123/339 (36%), Positives = 157/339 (46%), Gaps = 54/339 (15%)
Query: 482 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPG-RCENSP 540
C P C C++ P ++C C +GF L+ C DVDEC C G RC N
Sbjct: 3356 CSGGPSPCSHA-CLNAPGRFSCTCPTGFALAWDDRNCRDVDECAWDAHLCREGQRCVNLL 3414
Query: 541 GSFRCV--CGPGFRAGPRAAECLDVDECHRVPPPCDLGR-CENTPGSFLCVCPAGYQAAP 597
GS+RC+ CGPGFR A C DVDEC C + CENTPG C CP GY+
Sbjct: 3415 GSYRCLPDCGPGFRVAD-GAGCEDVDECLEGLDDCHYNQLCENTPGGHRCSCPRGYRMQG 3473
Query: 598 HGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFR----GSACE------EDVDEC 647
C DV+EC Q P C C NL GS+RC+CP G G AC ++V
Sbjct: 3474 PSLPCLDVNECLQLPKACAY-QCHNLQGSYRCLCPPGQTLLRDGKACTSLERNGQNVTTV 3532
Query: 648 AQEPP--PCGPGRCDNTAGSFH-----------------CACPAGF-RSRGPGAPCQDVD 687
+ P P S+H CP GF R G C D+D
Sbjct: 3533 SHRGPLLPWLRPWASIPGTSYHAWVSLRPGPMALSSVGRAWCPPGFIRQNG---VCTDLD 3589
Query: 688 ECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENH-LAC-PGQECVNS 745
EC R C + C NTEGS+QC+CP G++ +G C+D++ECE + C PGQ C N+
Sbjct: 3590 EC-RVRNLCQHA-CRNTEGSYQCLCPAGYRLLPSGKNCQDINECEEESIECGPGQMCFNT 3647
Query: 746 PGSFQCRTCPSGHHLHRG--------RCTDVDECSSGAP 776
GS+QC P +G RC+ +C +G P
Sbjct: 3648 RGSYQCVDTPCPATYRQGPSPGTCFRRCS--QDCGTGGP 3684
Score = 181 bits (460), Expect = 4e-45
Identities = 134/368 (36%), Positives = 170/368 (46%), Gaps = 62/368 (16%)
Query: 732 ENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSF 791
EN + CP ++S G+F C D DECS G PC H C N G F
Sbjct: 3332 ENEVGCPEGFELDSQGAF---------------CVDRDECSGGPSPCS-HA-CLNAPGRF 3374
Query: 792 RCSCAPGYRAPSGRPGPCADVNECL-EGDFCFPHGECLNTDGSFACT--CAPGYRPGPRG 848
C+C G+ A + C DV+EC + C C+N GS+ C C PG+R G
Sbjct: 3375 SCTCPTGF-ALAWDDRNCRDVDECAWDAHLCREGQRCVNLLGSYRCLPDCGPGFRVAD-G 3432
Query: 849 ASCLDVDECSE--EDLCQSGICTNTDGSFECICPPGHRA-GPDLASCLDVDECRERGPAL 905
A C DVDEC E +D + +C NT G C CP G+R GP L CLDV+EC + P
Sbjct: 3433 AGCEDVDECLEGLDDCHYNQLCENTPGGHRCSCPRGYRMQGPSLP-CLDVNECLQL-PKA 3490
Query: 906 CGSQRCENSPGSYRCVRDCDPGYHAGPEGTC--------DDVDECQEYGPEICGAQRCEN 957
C Q C N GSYRC+ C PG +G +V GP + + +
Sbjct: 3491 CAYQ-CHNLQGSYRCL--CPPGQTLLRDGKACTSLERNGQNVTTVSHRGPLLPWLRPWAS 3547
Query: 958 TPG-------SYRCTPA---------CDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNL 1001
PG S R P C PG+ G C D+DECR R+ C HA C+N
Sbjct: 3548 IPGTSYHAWVSLRPGPMALSSVGRAWCPPGFI-RQNGVCTDLDECRVRNLC-QHA-CRNT 3604
Query: 1002 PGSFQCLCDQGYEGARDGRHCVDVNECETLQGVCG-AALCENVEGSFLCV---CPNSPEE 1057
GS+QCLC GY G++C D+NECE CG +C N GS+ CV CP + +
Sbjct: 3605 EGSYQCLCPAGYRLLPSGKNCQDINECEEESIECGPGQMCFNTRGSYQCVDTPCPATYRQ 3664
Query: 1058 FDPMTGRC 1065
P G C
Sbjct: 3665 -GPSPGTC 3671
Score = 174 bits (440), Expect = 8e-43
Identities = 121/344 (35%), Positives = 151/344 (43%), Gaps = 48/344 (13%)
Query: 505 CDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAECLDVD 564
C GF L QG C+D DEC P PC+ C N+PG F C C GF C DVD
Sbjct: 3337 CPEGFELDSQGAFCVDRDECSGGPSPCSHA-CLNAPGRFSCTCPTGFALAWDDRNCRDVD 3395
Query: 565 ECHRVPPPCDLG-RCENTPGSFLCV--CPAGYQAAPHGASCQDVDECTQSPGLCG-RGAC 620
EC C G RC N GS+ C+ C G++ A GA C+DVDEC + C C
Sbjct: 3396 ECAWDAHLCREGQRCVNLLGSYRCLPDCGPGFRVA-DGAGCEDVDECLEGLDDCHYNQLC 3454
Query: 621 KNLPGSFRCVCPAGFR---GSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSR 677
+N PG RC CP G+R S DV+EC Q P C +C N GS+ C CP G
Sbjct: 3455 ENTPGGHRCSCPRGYRMQGPSLPCLDVNECLQLPKACA-YQCHNLQGSYRCLCPPGQTLL 3513
Query: 678 GPGAPCQDVDECAR-------------------SPPPCTYGRCENTEGSFQCV------- 711
G C ++ + S P +Y + +
Sbjct: 3514 RDGKACTSLERNGQNVTTVSHRGPLLPWLRPWASIPGTSYHAWVSLRPGPMALSSVGRAW 3573
Query: 712 CPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHL--HRGRCTDVD 769
CP GF C D+DEC C C N+ GS+QC CP+G+ L C D++
Sbjct: 3574 CPPGF--IRQNGVCTDLDECRVRNLCQ-HACRNTEGSYQC-LCPAGYRLLPSGKNCQDIN 3629
Query: 770 ECSSGAPPCGPHGHCTNTEGSFRC---SCAPGYR-APSGRPGPC 809
EC + CGP C NT GS++C C YR PS PG C
Sbjct: 3630 ECEEESIECGPGQMCFNTRGSYQCVDTPCPATYRQGPS--PGTC 3671
Score = 102 bits (255), Expect = 2e-21
Identities = 106/358 (29%), Positives = 146/358 (40%), Gaps = 60/358 (16%)
Query: 924 CDPGYHAGPEGT-CDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPT-PGGGCQ 981
C G+ +G C D DEC GP C + C N PG + CT C G+ C+
Sbjct: 3337 CPEGFELDSQGAFCVDRDECSG-GPSPC-SHACLNAPGRFSCT--CPTGFALAWDDRNCR 3392
Query: 982 DVDECR-NRSFCGAHAVCQNLPGSFQCL--CDQGYEGARDGRHCVDVNEC-ETLQGVCGA 1037
DVDEC + C C NL GS++CL C G+ A DG C DV+EC E L
Sbjct: 3393 DVDECAWDAHLCREGQRCVNLLGSYRCLPDCGPGFRVA-DGAGCEDVDECLEGLDDCHYN 3451
Query: 1038 ALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPL 1097
LCEN G C CP G + Q P+ P L L
Sbjct: 3452 QLCENTPGGHRCSCPR-----------------------GYRMQGPSLPCLDVNECLQ-L 3487
Query: 1098 PRRPSTPRQGPVGSGRRECY-FDTAAPD--ACDNIL--ARNVT----------WQECCCT 1142
P+ + GS R C T D AC ++ +NVT W +
Sbjct: 3488 PKACAYQCHNLQGSYRCLCPPGQTLLRDGKACTSLERNGQNVTTVSHRGPLLPWLRPWAS 3547
Query: 1143 V-GEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSG 1201
+ G + + ++ P ++ ++ CP G ++ +G + D+DEC++ +C+
Sbjct: 3548 IPGTSYHAWVSLRPGPMALSSVGRAWCPPG--FIRQNGVCT---DLDECRV--RNLCQHA 3600
Query: 1202 VCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGR-CVNTVGSYHCTCEP 1258
C NT Y C C GY C D +EC +E C G+ C NT GSY C P
Sbjct: 3601 -CRNTEGSYQCLCPAGYRLLPSGKNCQDINECEEESIECGPGQMCFNTRGSYQCVDTP 3657
Score = 89.7 bits (221), Expect = 2e-17
Identities = 85/323 (26%), Positives = 124/323 (38%), Gaps = 62/323 (19%)
Query: 251 AWGVHDC---QLCSERLGNSERVSAPDGPCPTGFERVNGS-CEDVDECATG-GRCQHGE- 304
AW H C Q C LG+ + PD C GF +G+ CEDVDEC G C + +
Sbjct: 3398 AWDAHLCREGQRCVNLLGSYRCL--PD--CGPGFRVADGAGCEDVDECLEGLDDCHYNQL 3453
Query: 305 CANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQIC 364
C NT GG+ C CP G+ + C+ + + C N+
Sbjct: 3454 CENTPGGHRCSCPRGYRMQGPSLPCLDVNECLQLPKACAYQ----------CHNLQGSYR 3503
Query: 365 CCSRVGKAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQP 424
C G+ R + C G N + P + +P
Sbjct: 3504 CLCPPGQTLLRDGKACTSLERNG-------------------QNVTTVSHRGPLLPWLRP 3544
Query: 425 -RTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSI-PAWTGPE-IPESGPSSGM 481
++P TS + L RPGP + L S+ AW P I ++G + +
Sbjct: 3545 WASIPGTSYHAWVSL---------------RPGP-MALSSVGRAWCPPGFIRQNGVCTDL 3588
Query: 482 CQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGR-CENSP 540
+ + C + Y C C +G+RL P G C D++EC C PG+ C N+
Sbjct: 3589 DECRVRNLCQHACRNTEGSYQCLCPAGYRLLPSGKNCQDINECEEESIECGPGQMCFNTR 3648
Query: 541 GSFRCV---CGPGFRAGPRAAEC 560
GS++CV C +R GP C
Sbjct: 3649 GSYQCVDTPCPATYRQGPSPGTC 3671
Score = 63.2 bits (152), Expect = 2e-09
Identities = 51/165 (30%), Positives = 64/165 (38%), Gaps = 16/165 (9%)
Query: 1112 GRRECYFDTAAPDACDNILARNV---TWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLC 1168
GR C T A D+ R+V W C G Q+C Y+ L
Sbjct: 3372 GRFSCTCPTGFALAWDDRNCRDVDECAWDAHLCREG---------QRCVNL-LGSYRCLP 3421
Query: 1169 PHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECI 1228
G G+ G + DVDEC D + +C NT G+ C C GY L C+
Sbjct: 3422 DCGPGFRVADG--AGCEDVDECLEGLDDCHYNQLCENTPGGHRCSCPRGYRMQGPSLPCL 3479
Query: 1229 DNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNE 1273
D +EC AC +C N GSY C C P L + C S E
Sbjct: 3480 DVNECLQLPKAC-AYQCHNLQGSYRCLCPPGQTLLRDGKACTSLE 3523
Score = 56.2 bits (134), Expect = 2e-07
Identities = 28/77 (36%), Positives = 39/77 (50%), Gaps = 6/77 (7%)
Query: 1466 EAEEC--GILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 1523
+ +EC G+ D N C P G C C GYR+ + C+D+NEC + P
Sbjct: 3437 DVDECLEGLDDCHYNQLCENTPGGHRCSCPRGYRMQGPSLPCLDVNECLQL----PKACA 3492
Query: 1524 ARCLNTDGSFRCICRPG 1540
+C N GS+RC+C PG
Sbjct: 3493 YQCHNLQGSYRCLCPPG 3509
Score = 54.3 bits (129), Expect = 9e-07
Identities = 46/132 (34%), Positives = 56/132 (42%), Gaps = 9/132 (6%)
Query: 1152 RIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYS 1211
R Q + E + CP G L G + RD EC C S C+N +S
Sbjct: 3321 RFQLATALQAEENEVGCPEGFE-LDSQGAFCVDRD--ECS-GGPSPC-SHACLNAPGRFS 3375
Query: 1212 CYCSNGYYYHTQRLECIDNDECADEEPAC-EGGRCVNTVGSYHC--TCEPPL-VLDGSQR 1267
C C G+ C D DECA + C EG RCVN +GSY C C P V DG+
Sbjct: 3376 CTCPTGFALAWDDRNCRDVDECAWDAHLCREGQRCVNLLGSYRCLPDCGPGFRVADGAGC 3435
Query: 1268 RCVSNESQSLDD 1279
V + LDD
Sbjct: 3436 EDVDECLEGLDD 3447
Score = 45.1 bits (105), Expect = 5e-04
Identities = 28/80 (35%), Positives = 37/80 (46%), Gaps = 10/80 (12%)
Query: 1470 CGILDGCTNG------RCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 1523
C D C+ G C+ P F+C C G+ L C D++EC A A
Sbjct: 3350 CVDRDECSGGPSPCSHACLNAPGRFSCTCPTGFALAWDDRNCRDVDEC--AWDAHLCREG 3407
Query: 1524 ARCLNTDGSFRCI--CRPGF 1541
RC+N GS+RC+ C PGF
Sbjct: 3408 QRCVNLLGSYRCLPDCGPGF 3427
Score = 45.1 bits (105), Expect = 5e-04
Identities = 24/74 (32%), Positives = 35/74 (47%), Gaps = 3/74 (4%)
Query: 1466 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNAR 1525
+ +EC + + C + C + C C GYRL + C DINEC+E
Sbjct: 3587 DLDECRVRNLCQHA-CRNTEGSYQCLCPAGYRLLPSGKNCQDINECEEESIECG--PGQM 3643
Query: 1526 CLNTDGSFRCICRP 1539
C NT GS++C+ P
Sbjct: 3644 CFNTRGSYQCVDTP 3657
Score = 42.0 bits (97), Expect = 0.005
Identities = 21/59 (35%), Positives = 27/59 (45%), Gaps = 4/59 (6%)
Query: 1492 CFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHC 1550
C +G+ LD CVD +EC + P + CLN G F C C GFA +C
Sbjct: 3337 CPEGFELDSQGAFCVDRDEC----SGGPSPCSHACLNAPGRFSCTCPTGFALAWDDRNC 3391
Score = 41.6 bits (96), Expect = 0.006
Identities = 20/68 (29%), Positives = 29/68 (42%), Gaps = 1/68 (1%)
Query: 1214 CSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNE 1273
C G+ +Q C+D DEC+ C C+N G + CTC L R C +
Sbjct: 3337 CPEGFELDSQGAFCVDRDECSGGPSPCSHA-CLNAPGRFSCTCPTGFALAWDDRNCRDVD 3395
Query: 1274 SQSLDDNL 1281
+ D +L
Sbjct: 3396 ECAWDAHL 3403
Score = 35.4 bits (80), Expect = 0.43
Identities = 23/69 (33%), Positives = 30/69 (43%), Gaps = 6/69 (8%)
Query: 1476 CTNG-RCVRVPEGFTCR--CFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGS 1532
C G RCV + + C C G+R+ C D++EC E N C NT G
Sbjct: 3404 CREGQRCVNLLGSYRCLPDCGPGFRV-ADGAGCEDVDEC--LEGLDDCHYNQLCENTPGG 3460
Query: 1533 FRCICRPGF 1541
RC C G+
Sbjct: 3461 HRCSCPRGY 3469
Score = 34.3 bits (77), Expect = 0.96
Identities = 15/37 (40%), Positives = 23/37 (62%), Gaps = 5/37 (13%)
Query: 1505 CVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGF 1541
C D++EC LC +A C NT+GS++C+C G+
Sbjct: 3585 CTDLDEC----RVRNLCQHA-CRNTEGSYQCLCPAGY 3616
>gi|122937283 6720455I24Rik homolog [Homo sapiens]
Length = 1413
Score = 211 bits (538), Expect = 3e-54
Identities = 187/632 (29%), Positives = 249/632 (39%), Gaps = 132/632 (20%)
Query: 494 CISRPSGYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCAPG-RCENSPGSFRCVCGPGF 551
C++ YTC+C SGF G RC +DV+EC PC G C + SFRC C GF
Sbjct: 288 CVTGNPSYTCSCLSGFT----GRRCHLDVNEC--ASQPCQNGGTCTHGINSFRCQCPAGF 341
Query: 552 RAGPRAAECLDVDECHRVPPPCDL------GRCENTPGSFLCVCPAGYQAAPHGASCQ-D 604
GP C PCD G+C+ GS +CVC AGY GA+C+ D
Sbjct: 342 -GGPT---------CETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYT----GAACEMD 387
Query: 605 VDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEED----VDECAQEPPPCGPGRCD 660
VD+C+ P L G G+C +L G++ C+C F+G CE D C P G G C
Sbjct: 388 VDDCSPDPCLNG-GSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNG-GTCV 445
Query: 661 NTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTY---GRCENTEGSFQCVCPMGF- 716
+ + C CP GF G C++ R P C GRC + C CP+GF
Sbjct: 446 DADQGYVCECPEGFM----GLDCRE-----RVPDDCECRNGGRCLGANTTL-CQCPLGFF 495
Query: 717 ----------QPNTAGSECEDVDECENH-------------------LACPGQECVNSPG 747
P ++C D C H C C N
Sbjct: 496 GLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGS 555
Query: 748 ------SFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCA---PG 798
S+ C CP G H CSSG PC G C G + CSC G
Sbjct: 556 CDAHDDSYTCE-CPRGFHGKHCEKARPHLCSSG--PCRNGGTCKEAGGEYHCSCPYRFTG 612
Query: 799 YRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASC-LDVDEC 857
G+P CA C G G C + G + C C PG+ G C + C
Sbjct: 613 RHCEIGKPDSCAS-GPCHNG------GTCFHYIGKYKCDCPPGFS----GRHCEIAPSPC 661
Query: 858 SEEDLCQSGICTNTDGSFECICPPGH--RAGPDLASCLDVDECRERGPALCGSQRCENSP 915
G C + D F C C G+ R C +E + G++ +
Sbjct: 662 FRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRL--GAV 719
Query: 916 GSYRC-----------VRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRC 964
Y C +R C P C ++DEC+ P + G C++ Y C
Sbjct: 720 ALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQ-PCLHGGS-CQDRVAGYLC 777
Query: 965 TPACDPGYQPTPGGGCQ-DVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHC- 1022
C GY+ G C+ + DECR C C+NLPG++ C C G+ G HC
Sbjct: 778 L--CSTGYE---GAHCELERDECRAHP-CRNGGSCRNLPGAYVCRCPAGFVGV----HCE 827
Query: 1023 VDVNECETLQGVCGAALCENVEGSFLCVCPNS 1054
+V+ C++ G CE+ G++LCVCP S
Sbjct: 828 TEVDACDSSPCQHGGR-CESGGGAYLCVCPES 858
Score = 182 bits (462), Expect = 2e-45
Identities = 174/620 (28%), Positives = 226/620 (36%), Gaps = 134/620 (21%)
Query: 500 GYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRAAE 559
G+T + R G +CID C S+ C C GF G R
Sbjct: 266 GHTTSVCLALRPCLNGGKCID--------------DCVTGNPSYTCSCLSGF-TGRRCH- 309
Query: 560 CLDVDECHRVPPPCDLG-RCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRG 618
LDV+EC PC G C + SF C CPAG+ G +C+ + G
Sbjct: 310 -LDVNEC--ASQPCQNGGTCTHGINSFRCQCPAGFG----GPTCETAQSPCDTKECQHGG 362
Query: 619 ACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPC-GPGRCDNTAGSFHCACPAGFRSR 677
C+ GS CVC AG+ G+ACE DVD+C+ P PC G C + G++ C C F+
Sbjct: 363 QCQVENGSAVCVCQAGYTGAACEMDVDDCS--PDPCLNGGSCVDLVGNYTCLCAEPFKGL 420
Query: 678 GPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLAC 737
V + S P G C + + + C CP GF D EC N C
Sbjct: 421 RCETGDHPVPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRC 480
Query: 738 PGQECV--NSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSC 795
G P F C + C +C G G+C GS+ C C
Sbjct: 481 LGANTTLCQCPLGFFGLLCE--FEITAMPCNMNTQCPDG-------GYCMEHGGSYLCVC 531
Query: 796 APGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVD 855
+ A P PC + D CF G C D S+ C C G+ G C
Sbjct: 532 HTDHNASHSLPSPC-------DSDPCFNGGSCDAHDDSYTCECPRGF----HGKHC---- 576
Query: 856 ECSEEDLCQSGICTN------TDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQ 909
E + LC SG C N G + C CP C P C S
Sbjct: 577 EKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTG----------RHCEIGKPDSCASG 626
Query: 910 RCENSP------GSYRCVRDCDPGY-----HAGPE----------GTCDDVD-----ECQ 943
C N G Y+C DC PG+ P GTC+D D CQ
Sbjct: 627 PCHNGGTCFHYIGKYKC--DCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQ 684
Query: 944 E-YGPEICGAQ--------------RCENTPGSYRCTPACDPGYQPT---------PGG- 978
Y C A+ R T ACD GY + P G
Sbjct: 685 AGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGV 744
Query: 979 -----GCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHC-VDVNECETLQ 1032
C ++DECR++ C CQ+ + CLC GYEGA HC ++ +EC
Sbjct: 745 WSEPPQCLEIDECRSQP-CLHGGSCQDRVAGYLCLCSTGYEGA----HCELERDECRAHP 799
Query: 1033 GVCGAALCENVEGSFLCVCP 1052
G + C N+ G+++C CP
Sbjct: 800 CRNGGS-CRNLPGAYVCRCP 818
Score = 169 bits (428), Expect = 2e-41
Identities = 193/715 (26%), Positives = 263/715 (36%), Gaps = 154/715 (21%)
Query: 575 LGRCENTPGSFLCVCPAGYQAAPHGASCQDVDEC-TQSPGLCGRGACKNLPGSFRCVCPA 633
+G C +T L + P +G C +D+C T +P S+ C C +
Sbjct: 262 VGGCGHTTSVCLALRPC-----LNGGKC--IDDCVTGNP-------------SYTCSCLS 301
Query: 634 GFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPG-----APCQDVDE 688
GF G C DV+ECA +P G G C + SF C CPAGF GP +PC D E
Sbjct: 302 GFTGRRCHLDVNECASQPCQNG-GTCTHGINSFRCQCPAGFG--GPTCETAQSPC-DTKE 357
Query: 689 CARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECE-DVDECENHLACPGQECVNSPG 747
C G+C+ GS CVC G+ G+ CE DVD+C G CV+ G
Sbjct: 358 CQHG------GQCQVENGSAVCVCQAGY----TGAACEMDVDDCSPDPCLNGGSCVDLVG 407
Query: 748 SFQCRTCP--SGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGR 805
++ C G G D C S PC G C + + + C C G+ R
Sbjct: 408 NYTCLCAEPFKGLRCETGDHPVPDACLSA--PCHNGGTCVDADQGYVCECPEGFMGLDCR 465
Query: 806 ---PGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASC---LDVDECSE 859
P C EC G G CL + + C C G+ G C + C+
Sbjct: 466 ERVPDDC----ECRNG------GRCLGANTTL-CQCPLGFF----GLLCEFEITAMPCNM 510
Query: 860 EDLC-QSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSY 918
C G C GS+ C+C H A L S D D C G C+ SY
Sbjct: 511 NTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGS-------CDAHDDSY 563
Query: 919 RCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCEN------TPGSYRCTPACDPGY 972
C +C G+H C++ P +C + C N G Y C+ C Y
Sbjct: 564 TC--ECPRGFHG---------KHCEKARPHLCSSGPCRNGGTCKEAGGEYHCS--CP--Y 608
Query: 973 QPTPGGGCQ--DVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECET 1030
+ T G C+ D C + C C + G ++C C G+ G RHC ++
Sbjct: 609 RFT-GRHCEIGKPDSCASGP-CHNGGTCFHYIGKYKCDCPPGFSG----RHC-EIAPSPC 661
Query: 1031 LQGVC-GAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLP 1089
+ C CE+ + F C C AG + G + QA P
Sbjct: 662 FRSPCVNGGTCEDRDTDFFCHC-------------------QAG-YMGRRCQAEVDCGPP 701
Query: 1090 ARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQEC--CCTVGEGW 1147
L R + R G V + + +AP + + W E C + E
Sbjct: 702 EEVKHATL--RFNGTRLGAVALYACDRGYSLSAPSRI-RVCQPHGVWSEPPQCLEIDE-- 756
Query: 1148 GSGCRIQQCPG-----TETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGV 1202
CR Q C A Y LC GY +L + DEC R C++G
Sbjct: 757 ---CRSQPCLHGGSCQDRVAGYLCLC--STGYEGAHCEL----ERDEC---RAHPCRNGG 804
Query: 1203 CVNTAPG-YSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTC 1256
PG Y C C G+ + C + D P GGRC + G+Y C C
Sbjct: 805 SCRNLPGAYVCRCPAGFV----GVHCETEVDACDSSPCQHGGRCESGGGAYLCVC 855
Score = 153 bits (387), Expect = 1e-36
Identities = 146/508 (28%), Positives = 189/508 (37%), Gaps = 79/508 (15%)
Query: 492 GRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPGF 551
G C+ GY C C GF R D ECR GRC + + C C GF
Sbjct: 442 GTCVDADQGYVCECPEGFMGLDCRERVPDDCECRN------GGRCLGANTTL-CQCPLGF 494
Query: 552 RAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQS 611
G + C+ D G C GS+LCVC + A+ S D D C
Sbjct: 495 -FGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNG 553
Query: 612 PGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACP 671
G+C S+ C CP GF G CE+ P G C G +HC+CP
Sbjct: 554 ------GSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCP 607
Query: 672 AGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDV-DE 730
+R G D CA S P G C + G ++C CP GF +G CE
Sbjct: 608 --YRFTGRHCEIGKPDSCA-SGPCHNGGTCFHYIGKYKCDCPPGF----SGRHCEIAPSP 660
Query: 731 CENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGP---------- 780
C G C + F C C +G ++ R +VD CGP
Sbjct: 661 CFRSPCVNGGTCEDRDTDFFCH-CQAG-YMGRRCQAEVD--------CGPPEEVKHATLR 710
Query: 781 -HGHCTNTEGSFRCSCAPGYRAPS-----------GRPGPCADVNECLEGDFCFPHGECL 828
+G + C APS P C +++EC C G C
Sbjct: 711 FNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDEC-RSQPCLHGGSCQ 769
Query: 829 NTDGSFACTCAPGYRPGPRGASC-LDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGP 887
+ + C C+ GY GA C L+ DEC G C N G++ C CP G
Sbjct: 770 DRVAGYLCLCSTGY----EGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVG-- 823
Query: 888 DLASC-LDVDECRERGPALCGSQRCENSPGSYRCV-RDCDPGYHAGPEGTCDDV-DECQE 944
C +VD C + P G RCE+ G+Y CV + GYH C+ V D C
Sbjct: 824 --VHCETEVDAC-DSSPCQHGG-RCESGGGAYLCVCPESFFGYH------CETVSDPC-- 871
Query: 945 YGPEICGAQRCENTPGSYRCTPACDPGY 972
+ G C + GS+ CT C GY
Sbjct: 872 FSSPCGGRGYCLASNGSHSCT--CKVGY 897
Score = 134 bits (336), Expect = 9e-31
Identities = 163/640 (25%), Positives = 211/640 (32%), Gaps = 174/640 (27%)
Query: 228 GGECASPLPGLRTQEVCCRGAG-----LAWGVHDCQLCSERLGNSERVSAPDGPCPTGFE 282
GG C + R Q C G G A D + C G +V C
Sbjct: 323 GGTCTHGINSFRCQ--CPAGFGGPTCETAQSPCDTKECQH--GGQCQVENGSAVCVCQAG 378
Query: 283 RVNGSCE-DVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEA--K 339
+CE DVD+C+ G C + G YTC+C + F H + +A
Sbjct: 379 YTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPF---KGLRCETGDHPVPDACLS 435
Query: 340 GPCFR----VLRDGG--CSLP------ILRNITKQICCCSRVGKAWGRGCQLCPPFGSEG 387
PC V D G C P R C C G+ G LC
Sbjct: 436 APCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRCLGANTTLCQ------ 489
Query: 388 FREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRP 447
CP G+ + P T P G+ H
Sbjct: 490 ----CPL--GFFGLLCEFEITAMPCNMN--------------TQCPDGGYCMEHGGSYLC 529
Query: 448 EPRPDPRPGPELPLP--SIPAWTGP-----------EIPESGPSSGMCQRNPQVC--GP- 491
D LP P S P + G E P + P +C GP
Sbjct: 530 VCHTDHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPC 589
Query: 492 ---GRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSP------GS 542
G C Y C+C F G C ++ + P CA G C N G
Sbjct: 590 RNGGTCKEAGGEYHCSCPYRF----TGRHC-EIGK----PDSCASGPCHNGGTCFHYIGK 640
Query: 543 FRCVCGPGFRAGPRAAECLDVDECHRVPPPC------DLGRCENTPGSFLCVCPAGYQ-- 594
++C C PGF C P PC + G CE+ F C C AGY
Sbjct: 641 YKCDCPPGFSG----------RHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGR 690
Query: 595 ------------------------------------------------AAPHGA-----S 601
PHG
Sbjct: 691 RCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQ 750
Query: 602 CQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDN 661
C ++DEC P L G G+C++ + C+C G+ G+ CE + DEC P G G C N
Sbjct: 751 CLEIDECRSQPCLHG-GSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNG-GSCRN 808
Query: 662 TAGSFHCACPAGFRSRGPGAPCQ-DVDECARSPPPCTY-GRCENTEGSFQCVCPMGFQPN 719
G++ C CPAGF G C+ +VD C S PC + GRCE+ G++ CVCP F
Sbjct: 809 LPGAYVCRCPAGF----VGVHCETEVDACDSS--PCQHGGRCESGGGAYLCVCPESF--- 859
Query: 720 TAGSECEDVDECENHLACPGQ-ECVNSPGSFQCRTCPSGH 758
G CE V + C G+ C+ S GS C TC G+
Sbjct: 860 -FGYHCETVSDPCFSSPCGGRGYCLASNGSHSC-TCKVGY 897
Score = 108 bits (270), Expect = 4e-23
Identities = 163/627 (25%), Positives = 209/627 (33%), Gaps = 163/627 (25%)
Query: 42 GLRCVHG--PTGSRCTPTCAPRNATSVDSGAPGGAAPGGPGFRAFLC------PLICHNG 93
GLRC G P C T VD+ G GF C C NG
Sbjct: 419 GLRCETGDHPVPDACLSAPCHNGGTCVDADQ-GYVCECPEGFMGLDCRERVPDDCECRNG 477
Query: 94 GVCVKPDR--CLCPPDFAGKFCQLHSSGARPPAPAVPGLTRSVYTMPLANHRDDEHGVAS 151
G C+ + C CP F G C+ + P Y M EHG +
Sbjct: 478 GRCLGANTTLCQCPLGFFGLLCEFEITAM--PCNMNTQCPDGGYCM--------EHGGSY 527
Query: 152 MVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAEAAARAEAAAPYTVLAQSAPRED 211
+ H +H S+ P + +A +D
Sbjct: 528 LCVCHTDHNASHSL--------PSPCDSDPCFNGGSCDA------------------HDD 561
Query: 212 GYSDASGFGYCFRELRGGECASPLPGLRTQEVCCRGAGL--AWGVHDCQLCSERLGNSER 269
Y+ C R G C P L + C G A G + C
Sbjct: 562 SYTCE-----CPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCS----------- 605
Query: 270 VSAPDGPCPTGFERVNGSCEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSC 329
CP F + D CA+G G C + G Y C CP GF S R
Sbjct: 606 -------CPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGF---SGRHCE 655
Query: 330 ISQHVISEAKGPCFR--VLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEG 387
I A PCFR + G C T C C GR CQ
Sbjct: 656 I-------APSPCFRSPCVNGGTCE----DRDTDFFCHCQ--AGYMGRRCQA-------- 694
Query: 388 FREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRP 447
E+ GP + LR+N LG L A R + P+ +P
Sbjct: 695 --EV-DCGPPEEVKHATLRFNGTRLGAV----------ALYACDRGYSLSAPSRIRVCQP 741
Query: 448 EPRPDPRPGPELPLPSIPAWTGP----EIPESGPSSGMCQRNPQVCGPGRCISRPSGYTC 503
W+ P EI E C+ P + G G C R +GY C
Sbjct: 742 HG----------------VWSEPPQCLEIDE-------CRSQPCLHG-GSCQDRVAGYLC 777
Query: 504 ACDSGFRLSPQGTRC-IDVDECRRVPPPCAPG-RCENSPGSFRCVCGPGFRAGPRAAEC- 560
C +G+ +G C ++ DECR PC G C N PG++ C C GF C
Sbjct: 778 LCSTGY----EGAHCELERDECRA--HPCRNGGSCRNLPGAYVCRCPAGFVG----VHCE 827
Query: 561 LDVDECHRVPPPCDLG-RCENTPGSFLCVCPAGYQAAPHGASCQDV-DECTQSPGLCG-R 617
+VD C PC G RCE+ G++LCVCP + G C+ V D C SP CG R
Sbjct: 828 TEVDACDS--SPCQHGGRCESGGGAYLCVCPESF----FGYHCETVSDPCFSSP--CGGR 879
Query: 618 GACKNLPGSFRCVCPAGFRGSACEEDV 644
G C GS C C G+ G C +++
Sbjct: 880 GYCLASNGSHSCTCKVGYTGEDCAKEL 906
Score = 75.5 bits (184), Expect = 4e-13
Identities = 115/449 (25%), Positives = 155/449 (34%), Gaps = 120/449 (26%)
Query: 851 CLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASC-LDVDECRERGPALCGSQ 909
CL+ +C ++ C + S+ C C G C LDV+EC + P G
Sbjct: 278 CLNGGKCIDD-------CVTGNPSYTCSCLSGFTG----RRCHLDVNECASQ-PCQNGGT 325
Query: 910 RCENSPGSYRCVRDCDPGYHAGPEGTCD------DVDECQEYGPEICGAQRCENTPGSYR 963
C + S+RC C G+ GP TC+ D ECQ G +C+ GS
Sbjct: 326 -CTHGINSFRC--QCPAGF-GGP--TCETAQSPCDTKECQHGG-------QCQVENGSAV 372
Query: 964 CTPACDPGYQPTPGGGCQ-DVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGAR----- 1017
C C GY G C+ DVD+C + C C +L G++ CLC + ++G R
Sbjct: 373 CV--CQAGYT---GAACEMDVDDC-SPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGD 426
Query: 1018 -------------DGRHCVDVNE---CETLQGVCGAALCENVEGSFLCVCPNSPEEFDPM 1061
+G CVD ++ CE +G G E V C C N
Sbjct: 427 HPVPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDD--CECRNG------- 477
Query: 1062 TGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPV----GSGRRECY 1117
GRC+ T+ P + A P P G GS C+
Sbjct: 478 -GRCLGANTTLCQCPLGFFGLLCEFEITAMP----CNMNTQCPDGGYCMEHGGSYLCVCH 532
Query: 1118 FDTAA----PDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRG 1173
D A P CD+ N G C Y CP RG
Sbjct: 533 TDHNASHSLPSPCDSDPCFN--------------GGSC------DAHDDSYTCECP--RG 570
Query: 1174 YLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAP----GYSCYCSNGYYYHTQRLECID 1229
+ C+ R +C SG C N G +CS Y + + E
Sbjct: 571 FHGK-----------HCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGK 619
Query: 1230 NDECADEEPACEGGRCVNTVGSYHCTCEP 1258
D CA P GG C + +G Y C C P
Sbjct: 620 PDSCASG-PCHNGGTCFHYIGKYKCDCPP 647
Score = 45.1 bits (105), Expect = 5e-04
Identities = 36/112 (32%), Positives = 49/112 (43%), Gaps = 19/112 (16%)
Query: 1203 CVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPL-- 1260
CV P Y+C C +G+ T R +D +ECA +P GG C + + S+ C C
Sbjct: 288 CVTGNPSYTCSCLSGF---TGRRCHLDVNECA-SQPCQNGGTCTHGINSFRCQCPAGFGG 343
Query: 1261 -VLDGSQRRCVSNESQSLDDNLGVCWQEVG-ADLVCSHPRLDRQATYTECCC 1310
+ +Q C + E Q + G C E G A VC QA YT C
Sbjct: 344 PTCETAQSPCDTKECQ----HGGQCQVENGSAVCVC-------QAGYTGAAC 384
Score = 42.0 bits (97), Expect = 0.005
Identities = 59/210 (28%), Positives = 76/210 (36%), Gaps = 46/210 (21%)
Query: 1135 TWQECCCTVGEGWGSGCRIQQCPGTETA-----EYQSLCPHGRGYLAPSGDLSLRR-DVD 1188
T + C V E C Q C T ++ CP G G P+ + + D
Sbjct: 304 TGRRCHLDVNE-----CASQPCQNGGTCTHGINSFRCQCPAGFG--GPTCETAQSPCDTK 356
Query: 1189 ECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNT 1248
ECQ G C C C GY T +D D+C+ + P GG CV+
Sbjct: 357 ECQ-------HGGQCQVENGSAVCVCQAGY---TGAACEMDVDDCSPD-PCLNGGSCVDL 405
Query: 1249 VGSYHCTCEPPLVLDGSQRRCVSNESQSLD-------DNLGVCWQEVGAD--LVCSHPR- 1298
VG+Y C C P RC + + D N G C V AD VC P
Sbjct: 406 VGNYTCLCAEPF----KGLRCETGDHPVPDACLSAPCHNGGTC---VDADQGYVCECPEG 458
Query: 1299 ---LD-RQATYTECCCLY-GEAWGMDCALC 1323
LD R+ +C C G G + LC
Sbjct: 459 FMGLDCRERVPDDCECRNGGRCLGANTTLC 488
Score = 40.8 bits (94), Expect = 0.010
Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 9/83 (10%)
Query: 1464 ELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMAC-VDINECDEAEAASPLCV 1522
ELE +EC G C +P + CRC G+ + C +++ CD +SP
Sbjct: 789 ELERDECRAHPCRNGGSCRNLPGAYVCRCPAGF----VGVHCETEVDACD----SSPCQH 840
Query: 1523 NARCLNTDGSFRCICRPGFAPTH 1545
RC + G++ C+C F H
Sbjct: 841 GGRCESGGGAYLCVCPESFFGYH 863
Score = 40.0 bits (92), Expect = 0.018
Identities = 26/77 (33%), Positives = 32/77 (41%), Gaps = 12/77 (15%)
Query: 1470 CGILDGCTNGR-----CVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNA 1524
C L C NG CV +TC C G+ R +D+NEC A+ P
Sbjct: 272 CLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFT---GRRCHLDVNEC----ASQPCQNGG 324
Query: 1525 RCLNTDGSFRCICRPGF 1541
C + SFRC C GF
Sbjct: 325 TCTHGINSFRCQCPAGF 341
Score = 37.7 bits (86), Expect = 0.087
Identities = 26/90 (28%), Positives = 35/90 (38%), Gaps = 7/90 (7%)
Query: 1456 GSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAE 1515
G +EP + LE +EC G C G+ C C GY + + +EC
Sbjct: 743 GVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCEL---ERDEC---- 795
Query: 1516 AASPLCVNARCLNTDGSFRCICRPGFAPTH 1545
A P C N G++ C C GF H
Sbjct: 796 RAHPCRNGGSCRNLPGAYVCRCPAGFVGVH 825
Score = 33.1 bits (74), Expect = 2.1
Identities = 27/98 (27%), Positives = 39/98 (39%), Gaps = 18/98 (18%)
Query: 1452 GSYAGSLAEPYEELEAE--ECGILDGCTN------GRCVRVPEGFTCRCFDGYRLDMTRM 1503
G+Y AEP++ L E + + D C + G CV +G+ C C +G+ R
Sbjct: 407 GNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRE 466
Query: 1504 ACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGF 1541
D EC RCL + + C C GF
Sbjct: 467 RVPDDCECRN---------GGRCLGANTTL-CQCPLGF 494
Score = 31.6 bits (70), Expect = 6.3
Identities = 22/82 (26%), Positives = 36/82 (43%), Gaps = 11/82 (13%)
Query: 1464 ELEAEECGILDGCTNG-RCVRVPEGFTCRC---FDGYRLDMTRMACVDINECDEAEAASP 1519
E++ ++C D C NG CV + +TC C F G R + + +A ++P
Sbjct: 385 EMDVDDCSP-DPCLNGGSCVDLVGNYTCLCAEPFKGLRCE------TGDHPVPDACLSAP 437
Query: 1520 LCVNARCLNTDGSFRCICRPGF 1541
C++ D + C C GF
Sbjct: 438 CHNGGTCVDADQGYVCECPEGF 459
Score = 31.2 bits (69), Expect = 8.2
Identities = 20/80 (25%), Positives = 29/80 (36%), Gaps = 13/80 (16%)
Query: 1465 LEAEECGILDGCTNGRCVRVPEGFTCRC---FDGYRLDMTRMACVDINECDEAEAASPLC 1521
L+ EC G C F C+C F G + + C D EC
Sbjct: 310 LDVNECASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPC-DTKECQH-------- 360
Query: 1522 VNARCLNTDGSFRCICRPGF 1541
+C +GS C+C+ G+
Sbjct: 361 -GGQCQVENGSAVCVCQAGY 379
Score = 31.2 bits (69), Expect = 8.2
Identities = 21/66 (31%), Positives = 28/66 (42%), Gaps = 12/66 (18%)
Query: 471 EIPESGPSS-----GMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECR 525
++PE G G C NP G G C+ ++C C GF+ G RC C
Sbjct: 1295 QLPEHGSKDIGNVPGNCSENPCQNG-GTCVPGADAHSCDCGPGFK----GRRC--ELACI 1347
Query: 526 RVPPPC 531
+V PC
Sbjct: 1348 KVSRPC 1353
>gi|4557679 jagged 1 precursor [Homo sapiens]
Length = 1218
Score = 202 bits (513), Expect = 3e-51
Identities = 172/621 (27%), Positives = 269/621 (43%), Gaps = 114/621 (18%)
Query: 481 MCQRNPQVCGP-------GRCISR-PSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCA 532
+C ++ CG G C + P Y C+C G+ G C ++ E + PC
Sbjct: 292 LCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGY----SGPNC-EIAEHACLSDPCH 346
Query: 533 P-GRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLG-RCENTPGSFLCVCP 590
G C+ + F C C PG+ GP + ++D+C P C G C++ F CVCP
Sbjct: 347 NRGSCKETSLGFECECSPGW-TGPTCST--NIDDCS--PNNCSHGGTCQDLVNGFKCVCP 401
Query: 591 AGYQAAPHGASCQ-DVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQ 649
+ G +CQ D +EC P + + +CKNL S+ C C G+ G C+ ++++C
Sbjct: 402 PQWT----GKTCQLDANECEAKPCVNAK-SCKNLIASYYCDCLPGWMGQNCDININDCL- 455
Query: 650 EPPPCGPGRCDNTAG------SFHCACPAGFRSRGPGAPCQ-DVDECARSPPPCTYGRCE 702
G+C N A + C CP G+ G C+ D+DECA S P G C+
Sbjct: 456 -------GQCQNDASCRDLVNGYRCICPPGYA----GDHCERDIDECA-SNPCLNGGHCQ 503
Query: 703 NTEGSFQCVCPMGFQPNTAGSECE-DVDECENHLACPGQECVNSPGSFQCRTCPSGH--- 758
N FQC+CP GF +G+ C+ D+D CE + G +C N + C+ CP +
Sbjct: 504 NEINRFQCLCPTGF----SGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCK-CPEDYEGK 558
Query: 759 -------HLHRGRCTDVDEC-----SSGAPP---------CGPHGHC-TNTEGSFRCSCA 796
H C +D C S+ P CGPHG C + + G F C C
Sbjct: 559 NCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCN 618
Query: 797 PGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASC-LDVD 855
G+ ++N+C E + C G C++ S+ C C+ G+ GA C +++
Sbjct: 619 KGFTGTYCHE----NINDC-ESNPCRNGGTCIDGVNSYKCICSDGWE----GAYCETNIN 669
Query: 856 ECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVD-ECRERGPALCGSQ-RCEN 913
+CS+ G C + F C C G + +C D +C E A C + C +
Sbjct: 670 DCSQNPCHNGGTCRDLVNDFYCDCKNGWKG----KTCHSRDSQCDE---ATCNNGGTCYD 722
Query: 914 SPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEIC-GAQRCENTPGSYRCTPACDPGY 972
+++C+ C G+ EGT ++ P C C S+ C C G+
Sbjct: 723 EGDAFKCM--CPGGW----EGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCV--CKEGW 774
Query: 973 QPTPGGGC-QDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECETL 1031
+ G C Q+ ++C C C + ++C C G+ G D R +++NEC++
Sbjct: 775 E---GPICAQNTNDCSPHP-CYNSGTCVDGDNWYRCECAPGFAGP-DCR--ININECQSS 827
Query: 1032 QGVCGAALCENVEGSFLCVCP 1052
GA + + G + CVCP
Sbjct: 828 PCAFGATCVDEING-YRCVCP 847
Score = 195 bits (496), Expect = 3e-49
Identities = 174/647 (26%), Positives = 269/647 (41%), Gaps = 126/647 (19%)
Query: 456 GPELPLPSIP-AWTGP--EIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLS 512
GP+ S P ++GP EI E S C G C G+ C C G+
Sbjct: 316 GPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNR------GSCKETSLGFECECSPGWT-- 367
Query: 513 PQGTRC-IDVDECRRVPPPCAPG-RCENSPGSFRCVCGPGFRAGPRAAEC-LDVDECHRV 569
G C ++D+C P C+ G C++ F+CVC P + C LD +EC
Sbjct: 368 --GPTCSTNIDDCS--PNNCSHGGTCQDLVNGFKCVCPPQWTG----KTCQLDANECE-A 418
Query: 570 PPPCDLGRCENTPGSFLCVCPAGYQAAPHGASCQ-DVDECTQSPGLCGRGA-CKNLPGSF 627
P + C+N S+ C C G+ G +C ++++C G C A C++L +
Sbjct: 419 KPCVNAKSCKNLIASYYCDCLPGWM----GQNCDININDCL---GQCQNDASCRDLVNGY 471
Query: 628 RCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQ-DV 686
RC+CP G+ G CE D+DECA P G G C N F C CP GF G CQ D+
Sbjct: 472 RCICPPGYAGDHCERDIDECASNPCLNG-GHCQNEINRFQCLCPTGF----SGNLCQLDI 526
Query: 687 DECARSPPPCTYG-RCENTEGSFQCVCPMGFQPNTAG--------SECEDVDEC------ 731
D C P PC G +C N + C CP ++ + CE +D C
Sbjct: 527 DYC--EPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMAS 584
Query: 732 ----------ENHLACPGQECVNSPG---SFQCRTCPSGHHLHRGRCTDVDECSSGAPPC 778
+++ P +C + G + C +G + H ++++C S PC
Sbjct: 585 NDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHE----NINDCESN--PC 638
Query: 779 GPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTC 838
G C + S++C C+ G+ ++N+C + C G C + F C C
Sbjct: 639 RNGGTCIDGVNSYKCICSDGWEGAYCE----TNINDCSQNP-CHNGGTCRDLVNDFYCDC 693
Query: 839 APGYRPGPRGASCLDVD-ECSEEDLCQSGICTNTDGSFECICPPGHRAG----PDLASCL 893
G+ +G +C D +C E G C + +F+C+CP G +SCL
Sbjct: 694 KNGW----KGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCL 749
Query: 894 DVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEIC-GA 952
+ C G + + S+ CV C G+ GP + ++C P C +
Sbjct: 750 P-NPCHNGGTCVVNGE-------SFTCV--CKEGWE-GPI-CAQNTNDC---SPHPCYNS 794
Query: 953 QRCENTPGSYRCTPACDPGYQPTPGGGCQ-DVDECRNRSFCGAHAVCQNLPGSFQCLCDQ 1011
C + YRC C PG+ G C+ +++EC++ S C A C + ++C+C
Sbjct: 795 GTCVDGDNWYRC--ECAPGF---AGPDCRININECQS-SPCAFGATCVDEINGYRCVCPP 848
Query: 1012 GYEGAR----DGRHCVDV-----------NECETLQGVCGAALCENV 1043
G+ GA+ GR C+ + ++C T Q + G C V
Sbjct: 849 GHSGAKCQEVSGRPCITMGSVIPDGAKWDDDCNTCQCLNGRIACSKV 895
Score = 169 bits (427), Expect = 3e-41
Identities = 181/750 (24%), Positives = 274/750 (36%), Gaps = 127/750 (16%)
Query: 576 GRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGF 635
G C+ PG C C G+Q G C D+C PG C G C ++C+C +
Sbjct: 243 GSCK-LPGD--CRCQYGWQ----GLYC---DKCIPHPG-CVHGICNE---PWQCLCETNW 288
Query: 636 RGSACEEDVDECAQEPPPCGPGRCDNTA-GSFHCACPAGFRSRGPGAPCQDVDECARSPP 694
G C++D++ C P G C NT + C+CP G+ G C+ + S P
Sbjct: 289 GGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGY----SGPNCEIAEHACLSDP 344
Query: 695 PCTYGRCENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTC 754
G C+ T F+C C G+ T + ++D+C + G C + F+C C
Sbjct: 345 CHNRGSCKETSLGFECECSPGWTGPTCST---NIDDCSPNNCSHGGTCQDLVNGFKC-VC 400
Query: 755 PSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPC-ADVN 813
P G+ +D A PC C N S+ C C PG+ + C ++N
Sbjct: 401 PP---QWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQN-----CDININ 452
Query: 814 ECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASC-LDVDECSEEDLCQSGICTNTD 872
+CL C C + + C C PGY G C D+DEC+ G C N
Sbjct: 453 DCL--GQCQNDASCRDLVNGYRCICPPGY----AGDHCERDIDECASNPCLNGGHCQNEI 506
Query: 873 GSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCV-------RDCD 925
F+C+CP G LD+D C E P G+Q C N Y C ++C
Sbjct: 507 NRFQCLCPTGFSGN---LCQLDIDYC-EPNPCQNGAQ-CYNRASDYFCKCPEDYEGKNCS 561
Query: 926 PGYHAGPEGTCDDVDEC-------------QEYGPEICGAQ-RCENTPGSYRCTPACDPG 971
C+ +D C + +CG +C++ G + T C+ G
Sbjct: 562 HLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGG-KFTCDCNKG 620
Query: 972 YQPTPGGGC-QDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHC-VDVNECE 1029
+ G C +++++C + C C + S++C+C G+EGA +C ++N+C
Sbjct: 621 F---TGTYCHENINDCESNP-CRNGGTCIDGVNSYKCICSDGWEGA----YCETNINDCS 672
Query: 1030 TLQGVC-GAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVL 1088
Q C C ++ F C C N + T + T
Sbjct: 673 --QNPCHNGGTCRDLVNDFYCDCKNG---WKGKTCHSRDSQCDEATCNNGGTCYDEGDAF 727
Query: 1089 PARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGW- 1147
P G G+ + P+ C N V + C EGW
Sbjct: 728 KCMCP------------GGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWE 775
Query: 1148 -------GSGCRIQQCPGTET---AEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQV 1197
+ C C + T + C G+ P R +++ECQ
Sbjct: 776 GPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPGFAGP----DCRININECQ---SSP 828
Query: 1198 CKSG-VCVNTAPGYSCYCSNGY----YYHTQRLECIDN----DECADEEPACEGGRCVNT 1248
C G CV+ GY C C G+ CI + A + C +C+N
Sbjct: 829 CAFGATCVDEINGYRCVCPPGHSGAKCQEVSGRPCITMGSVIPDGAKWDDDCNTCQCLN- 887
Query: 1249 VGSYHCT---CEP-PLVLDGSQRRCVSNES 1274
G C+ C P P +L C S +S
Sbjct: 888 -GRIACSKVWCGPRPCLLHKGHSECPSGQS 916
Score = 144 bits (363), Expect = 7e-34
Identities = 158/581 (27%), Positives = 225/581 (38%), Gaps = 89/581 (15%)
Query: 688 ECARSPPPCTYGRCENTEGSFQ----CVCPMGFQPNTAGSECEDVDECENHLACPGQECV 743
EC R+ C G C GS + C C G+Q G C D+C H C C
Sbjct: 228 ECNRAI--CRQG-CSPKHGSCKLPGDCRCQYGWQ----GLYC---DKCIPHPGCVHGIC- 276
Query: 744 NSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNT-EGSFRCSCAPGYRAP 802
N P C T G + D++ C + P C G C+NT ++CSC GY P
Sbjct: 277 NEPWQCLCETNWGGQLCDK----DLNYCGTHQP-CLNGGTCSNTGPDKYQCSCPEGYSGP 331
Query: 803 SGRPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASC-LDVDECSEED 861
+ C D C G C T F C C+PG+ G +C ++D+CS +
Sbjct: 332 N-----CEIAEHACLSDPCHNRGSCKETSLGFECECSPGWT----GPTCSTNIDDCSPNN 382
Query: 862 LCQSGICTNTDGSFECICPPGHRAGPDLASC-LDVDECRERGPALCGSQRCENSPGSYRC 920
G C + F+C+CPP +C LD +EC E P + ++ C+N SY C
Sbjct: 383 CSHGGTCQDLVNGFKCVCPPQWTG----KTCQLDANEC-EAKPCV-NAKSCKNLIASYYC 436
Query: 921 VRDCDPGYHAGPEGTCD-DVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGG 979
DC PG+ CD ++++C + C + YRC C PGY G
Sbjct: 437 --DCLPGWMGQ---NCDININDCLG---QCQNDASCRDLVNGYRCI--CPPGYA---GDH 483
Query: 980 CQ-DVDECR-NRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHC-VDVNECETLQGVCG 1036
C+ D+DEC N G H CQN FQCLC G+ G C +D++ CE G
Sbjct: 484 CERDIDECASNPCLNGGH--CQNEINRFQCLCPTGFSG----NLCQLDIDYCEPNPCQNG 537
Query: 1037 AALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPP 1096
A C N + C CP E + C + T P + V A P
Sbjct: 538 AQ-CYNRASDYFCKCPEDYEGKN-----CSHLKDHCRTTPCEV--IDSCTVAMASNDTPE 589
Query: 1097 LPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQC 1156
R S+ GP G +C + CD + T C + + + CR
Sbjct: 590 GVRYISSNVCGPHG----KCKSQSGGKFTCD--CNKGFTGTYCHENINDCESNPCRNGGT 643
Query: 1157 PGTETAEYQSLCPHG-RGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCS 1215
Y+ +C G G + ++++C ++ G C + + C C
Sbjct: 644 CIDGVNSYKCICSDGWEGAYCET-------NINDCS--QNPCHNGGTCRDLVNDFYCDCK 694
Query: 1216 NGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTC 1256
NG+ T C D DE GG C + ++ C C
Sbjct: 695 NGWKGKT----CHSRDSQCDEATCNNGGTCYDEGDAFKCMC 731
Score = 85.9 bits (211), Expect = 3e-16
Identities = 141/594 (23%), Positives = 217/594 (36%), Gaps = 125/594 (21%)
Query: 778 CGPHGHCTNTEGSF--RCSCAPGYRAPSGRPGPCADVNEC--------LEGDFCFPHGEC 827
C +G+ T EG C+ A + S + G C +C L D C PH C
Sbjct: 212 CDQNGNKTCMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHPGC 271
Query: 828 LN--TDGSFACTCAPGYRPGPRGASC-LDVDECSEEDLC-QSGICTNTD-GSFECICPPG 882
++ + + C C + G C D++ C C G C+NT ++C CP G
Sbjct: 272 VHGICNEPWQCLCETNWG----GQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEG 327
Query: 883 HRAGPDLA----SCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCD- 937
+ +GP+ +CL D C RG C+ + + C +C PG+ GP TC
Sbjct: 328 Y-SGPNCEIAEHACLS-DPCHNRGS-------CKETSLGFEC--ECSPGW-TGP--TCST 373
Query: 938 DVDECQEYGPEICG-AQRCENTPGSYRCTPACDPGYQPTPGGGCQ-DVDECRNRSFCGAH 995
++D+C P C C++ ++C C P + G CQ D +EC + A
Sbjct: 374 NIDDCS---PNNCSHGGTCQDLVNGFKCV--CPPQWT---GKTCQLDANECEAKPCVNAK 425
Query: 996 AVCQNLPGSFQCLCDQGYEGARDGRHC-VDVNECETLQGVC-GAALCENVEGSFLCVCPN 1053
+ C+NL S+ C C G+ G ++C +++N+C G C A C ++ + C+C
Sbjct: 426 S-CKNLIASYYCDCLPGWMG----QNCDININDC---LGQCQNDASCRDLVNGYRCIC-- 475
Query: 1054 SPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGR 1113
PP + + ++P L + R P G
Sbjct: 476 -------------PPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLC---PTGFSG 519
Query: 1114 RECYFDT--AAPDACDNILARNVTWQECCCTVGEGW-GSGCRI--QQCPGTETAEYQSLC 1168
C D P+ C N + C E + G C C T S
Sbjct: 520 NLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCT 579
Query: 1169 PHGRGYLAPSGDLSLRRDVDECQLFRDQVC-KSGVCVNTAPG-YSCYCSNGYYYHTQRLE 1226
P G + VC G C + + G ++C C+ G+
Sbjct: 580 VAMASNDTPEG----------VRYISSNVCGPHGKCKSQSGGKFTCDCNKGF----TGTY 625
Query: 1227 CIDNDECADEEPACEGGRCVNTVGSYHCTCEPPLVLDGSQ----RRCVSNESQSLDDNLG 1282
C +N + P GG C++ V SY C C DG + +++ SQ+ N G
Sbjct: 626 CHENINDCESNPCRNGGTCIDGVNSYKCICS-----DGWEGAYCETNINDCSQNPCHNGG 680
Query: 1283 VCWQEVGADLVCSHPRLDRQATYTECCCLYGEAWGMDCALCPAQDSDDFEALCN 1336
C DLV Y +C G C ++DS EA CN
Sbjct: 681 TC-----RDLV--------NDFYCDC------KNGWKGKTCHSRDSQCDEATCN 715
Score = 39.7 bits (91), Expect = 0.023
Identities = 20/63 (31%), Positives = 30/63 (47%), Gaps = 7/63 (11%)
Query: 1478 NGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCIC 1537
+G CV + C C G+ R ++INEC +SP A C++ +RC+C
Sbjct: 794 SGTCVDGDNWYRCECAPGFAGPDCR---ININECQ----SSPCAFGATCVDEINGYRCVC 846
Query: 1538 RPG 1540
PG
Sbjct: 847 PPG 849
Score = 39.3 bits (90), Expect = 0.030
Identities = 18/45 (40%), Positives = 23/45 (51%), Gaps = 3/45 (6%)
Query: 277 CPTGFERVNGSCE-DVDECATGGRCQHGECANTRGGYTCVCPDGF 320
CP G+ CE D+DECA+ G C N + C+CP GF
Sbjct: 475 CPPGY--AGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGF 517
Score = 38.9 bits (89), Expect = 0.039
Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 12/84 (14%)
Query: 1464 ELEAEECGILDGCTNGR-CVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCV 1522
+L+A EC C N + C + + C C G+ M + ++IN+C C
Sbjct: 410 QLDANECEAKP-CVNAKSCKNLIASYYCDCLPGW---MGQNCDININDC------LGQCQ 459
Query: 1523 N-ARCLNTDGSFRCICRPGFAPTH 1545
N A C + +RCIC PG+A H
Sbjct: 460 NDASCRDLVNGYRCICPPGYAGDH 483
Score = 38.9 bits (89), Expect = 0.039
Identities = 23/68 (33%), Positives = 33/68 (48%), Gaps = 8/68 (11%)
Query: 1476 CTNG-RCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFR 1534
C NG CV E FTC C +G+ + + N+C + P + C++ D +R
Sbjct: 753 CHNGGTCVVNGESFTCVCKEGWE---GPICAQNTNDC----SPHPCYNSGTCVDGDNWYR 805
Query: 1535 CICRPGFA 1542
C C PGFA
Sbjct: 806 CECAPGFA 813
Score = 38.5 bits (88), Expect = 0.051
Identities = 29/105 (27%), Positives = 43/105 (40%), Gaps = 14/105 (13%)
Query: 1200 SGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEP- 1258
SG CV+ Y C C+ G+ R I+ +EC P G CV+ + Y C C P
Sbjct: 794 SGTCVDGDNWYRCECAPGFAGPDCR---ININEC-QSSPCAFGATCVDEINGYRCVCPPG 849
Query: 1259 ---PLVLDGSQRRCVS-----NESQSLDDNLGVCWQEVGADLVCS 1295
+ S R C++ + DD+ C Q + + CS
Sbjct: 850 HSGAKCQEVSGRPCITMGSVIPDGAKWDDDCNTC-QCLNGRIACS 893
Score = 36.6 bits (83), Expect = 0.19
Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 10/80 (12%)
Query: 1464 ELEAEECGILDGCTN-GRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCV 1522
++ +C L C N C + G+ C C GY D DI+EC A++P
Sbjct: 448 DININDC--LGQCQNDASCRDLVNGYRCICPPGYAGDHCER---DIDEC----ASNPCLN 498
Query: 1523 NARCLNTDGSFRCICRPGFA 1542
C N F+C+C GF+
Sbjct: 499 GGHCQNEINRFQCLCPTGFS 518
Score = 36.2 bits (82), Expect = 0.25
Identities = 24/77 (31%), Positives = 34/77 (44%), Gaps = 27/77 (35%)
Query: 45 CVHGPTGSRCTPTCAPRNATSVDSGAPGGAAPGGPGFRAFLCPLICHNGGVC---VKPDR 101
C G TG PTC+ T++D +P C +GG C V +
Sbjct: 362 CSPGWTG----PTCS----TNIDDCSPNN----------------CSHGGTCQDLVNGFK 397
Query: 102 CLCPPDFAGKFCQLHSS 118
C+CPP + GK CQL ++
Sbjct: 398 CVCPPQWTGKTCQLDAN 414
Score = 33.9 bits (76), Expect = 1.3
Identities = 18/46 (39%), Positives = 24/46 (52%), Gaps = 5/46 (10%)
Query: 277 CPTGFERVNGSCE-DVDECATGGRCQHG-ECANTRGGYTCVCPDGF 320
CPTGF C+ D+D C CQ+G +C N Y C CP+ +
Sbjct: 513 CPTGFS--GNLCQLDIDYCEPNP-CQNGAQCYNRASDYFCKCPEDY 555
Score = 33.9 bits (76), Expect = 1.3
Identities = 15/33 (45%), Positives = 19/33 (57%), Gaps = 3/33 (9%)
Query: 87 PLICHNGGVCVKPD---RCLCPPDFAGKFCQLH 116
P C+N G CV D RC C P FAG C+++
Sbjct: 788 PHPCYNSGTCVDGDNWYRCECAPGFAGPDCRIN 820
Score = 33.1 bits (74), Expect = 2.1
Identities = 15/36 (41%), Positives = 18/36 (50%), Gaps = 3/36 (8%)
Query: 90 CHNGGVC---VKPDRCLCPPDFAGKFCQLHSSGARP 122
C NGG C + +CLCP F+G CQL P
Sbjct: 496 CLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEP 531
Score = 31.2 bits (69), Expect = 8.2
Identities = 21/74 (28%), Positives = 28/74 (37%), Gaps = 9/74 (12%)
Query: 1470 CGILDGCTNG-RCVRV-PEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCL 1527
CG C NG C P+ + C C +GY +A + A + P C
Sbjct: 300 CGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIA-------EHACLSDPCHNRGSCK 352
Query: 1528 NTDGSFRCICRPGF 1541
T F C C PG+
Sbjct: 353 ETSLGFECECSPGW 366
Score = 31.2 bits (69), Expect = 8.2
Identities = 20/66 (30%), Positives = 33/66 (50%), Gaps = 10/66 (15%)
Query: 1478 NGRCVRVPEG-FTCRCFDGYRLDMTRMACVD-INECDEAEAASPLCVNARCLNTDGSFRC 1535
+G+C G FTC C G+ T C + IN+C+ ++P C++ S++C
Sbjct: 602 HGKCKSQSGGKFTCDCNKGF----TGTYCHENINDCE----SNPCRNGGTCIDGVNSYKC 653
Query: 1536 ICRPGF 1541
IC G+
Sbjct: 654 ICSDGW 659
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.140 0.489
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 95,188,996
Number of Sequences: 37866
Number of extensions: 6723959
Number of successful extensions: 63880
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 325
Number of HSP's successfully gapped in prelim test: 1001
Number of HSP's that attempted gapping in prelim test: 29160
Number of HSP's gapped (non-prelim): 19006
length of query: 1557
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1441
effective length of database: 13,855,062
effective search space: 19965144342
effective search space used: 19965144342
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.