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Search of human proteins with 15011941
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo
sapiens]
(474 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo sa... 984 0.0
gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo s... 970 0.0
gi|21630277 tripartite motif-containing 11 [Homo sapiens] 305 6e-83
gi|112421127 tripartite motif-containing 58 [Homo sapiens] 300 1e-81
gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens] 291 7e-79
gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens] 291 7e-79
gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens] 267 2e-71
gi|15208660 tripartite motif protein 21 [Homo sapiens] 261 7e-70
gi|68160935 tripartite motif-containing 17 isoform 2 [Homo sapiens] 260 2e-69
gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens] 257 1e-68
gi|5730009 ret finger protein [Homo sapiens] 251 8e-67
gi|157743261 tripartite motif-containing 75 [Homo sapiens] 250 2e-66
gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens] 248 9e-66
gi|37622899 ring finger protein 137 [Homo sapiens] 243 2e-64
gi|5454014 tripartite motif-containing 38 [Homo sapiens] 234 1e-61
gi|198442878 tripartite motif-containing 17 isoform 3 [Homo sapi... 219 3e-57
gi|20270353 tripartite motif-containing 43 [Homo sapiens] 218 1e-56
gi|22749269 ring finger protein 129 [Homo sapiens] 217 2e-56
gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens] 214 1e-55
gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens] 214 1e-55
gi|31542779 tripartite motif family-like 1 [Homo sapiens] 214 1e-55
gi|157426898 tripartite motif-containing 10 isoform 1 [Homo sapi... 211 2e-54
gi|88953346 PREDICTED: Tripartite motif-containing protein 43-li... 210 2e-54
gi|210147600 tripartite motif-containing 64 [Homo sapiens] 199 6e-51
gi|169202375 PREDICTED: tripartite motif-containing protein 64B-... 199 6e-51
gi|14719418 tripartite motif protein TRIM5 isoform alpha [Homo s... 196 3e-50
gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens] 193 2e-49
gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens] 193 2e-49
gi|51477690 tripartite motif-containing 6 and tripartite motif-c... 193 2e-49
gi|239755488 PREDICTED: similar to ring finger protein 18 isofor... 190 2e-48
>gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo
sapiens]
Length = 474
Score = 984 bits (2545), Expect = 0.0
Identities = 474/474 (100%), Positives = 474/474 (100%)
Query: 1 MEAEDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAA 60
MEAEDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAA
Sbjct: 1 MEAEDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAA 60
Query: 61 LRPNWALARLTEKTQRRRLGPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHAM 120
LRPNWALARLTEKTQRRRLGPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHAM
Sbjct: 61 LRPNWALARLTEKTQRRRLGPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHAM 120
Query: 121 APIDEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRISTEFSKL 180
APIDEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRISTEFSKL
Sbjct: 121 APIDEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRISTEFSKL 180
Query: 181 HNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAPTLELLQ 240
HNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAPTLELLQ
Sbjct: 181 HNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAPTLELLQ 240
Query: 241 NPKEVLTRSEIQDVNYSLEAVKVKTVCQIPLMKEMLKRFQVAVNLAEDTAHPKLVFSQEG 300
NPKEVLTRSEIQDVNYSLEAVKVKTVCQIPLMKEMLKRFQVAVNLAEDTAHPKLVFSQEG
Sbjct: 241 NPKEVLTRSEIQDVNYSLEAVKVKTVCQIPLMKEMLKRFQVAVNLAEDTAHPKLVFSQEG 300
Query: 301 RYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHLPCVLGKNVFTSGKHYWEVES 360
RYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHLPCVLGKNVFTSGKHYWEVES
Sbjct: 301 RYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHLPCVLGKNVFTSGKHYWEVES 360
Query: 361 RDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIYWSAAGYWPLIGFPGTPTQQEPALHRV 420
RDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIYWSAAGYWPLIGFPGTPTQQEPALHRV
Sbjct: 361 RDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIYWSAAGYWPLIGFPGTPTQQEPALHRV 420
Query: 421 GVYLDRGTGNVSFYSAVDGVHLHTFSCSSVSRLRPFFWLSPLASLVIPPVTDRK 474
GVYLDRGTGNVSFYSAVDGVHLHTFSCSSVSRLRPFFWLSPLASLVIPPVTDRK
Sbjct: 421 GVYLDRGTGNVSFYSAVDGVHLHTFSCSSVSRLRPFFWLSPLASLVIPPVTDRK 474
>gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo
sapiens]
Length = 500
Score = 970 bits (2508), Expect = 0.0
Identities = 474/500 (94%), Positives = 474/500 (94%), Gaps = 26/500 (5%)
Query: 1 MEAEDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAA 60
MEAEDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAA
Sbjct: 1 MEAEDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAA 60
Query: 61 LRPNWALARLTEKTQRRRLGPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHAM 120
LRPNWALARLTEKTQRRRLGPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHAM
Sbjct: 61 LRPNWALARLTEKTQRRRLGPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHAM 120
Query: 121 APIDEAFESYR--------------------------EKLLKSQRNLVAKMKKVMHLQDV 154
APIDEAFESYR EKLLKSQRNLVAKMKKVMHLQDV
Sbjct: 121 APIDEAFESYRTGNFDIHVDEWKRRLIRLLLYHSKQEEKLLKSQRNLVAKMKKVMHLQDV 180
Query: 155 EVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLN 214
EVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLN
Sbjct: 181 EVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLN 240
Query: 215 QTIASLKKLILEVGEKSQAPTLELLQNPKEVLTRSEIQDVNYSLEAVKVKTVCQIPLMKE 274
QTIASLKKLILEVGEKSQAPTLELLQNPKEVLTRSEIQDVNYSLEAVKVKTVCQIPLMKE
Sbjct: 241 QTIASLKKLILEVGEKSQAPTLELLQNPKEVLTRSEIQDVNYSLEAVKVKTVCQIPLMKE 300
Query: 275 MLKRFQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFV 334
MLKRFQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFV
Sbjct: 301 MLKRFQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFV 360
Query: 335 ERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIY 394
ERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIY
Sbjct: 361 ERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIY 420
Query: 395 WSAAGYWPLIGFPGTPTQQEPALHRVGVYLDRGTGNVSFYSAVDGVHLHTFSCSSVSRLR 454
WSAAGYWPLIGFPGTPTQQEPALHRVGVYLDRGTGNVSFYSAVDGVHLHTFSCSSVSRLR
Sbjct: 421 WSAAGYWPLIGFPGTPTQQEPALHRVGVYLDRGTGNVSFYSAVDGVHLHTFSCSSVSRLR 480
Query: 455 PFFWLSPLASLVIPPVTDRK 474
PFFWLSPLASLVIPPVTDRK
Sbjct: 481 PFFWLSPLASLVIPPVTDRK 500
>gi|21630277 tripartite motif-containing 11 [Homo sapiens]
Length = 468
Score = 305 bits (781), Expect = 6e-83
Identities = 185/469 (39%), Positives = 253/469 (53%), Gaps = 31/469 (6%)
Query: 5 DIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAALRPN 64
++QEE TC ICLDYF DPV +CGHNFCR C+ R W GP+ CPECR S LRPN
Sbjct: 9 NLQEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQPEGPYACPECRELSPQRNLRPN 68
Query: 65 WALARLTEKTQRRRL-GPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHAMAPI 123
LA++ E +R PVP G+C H EPL FC D+ R +C C S EH H + P+
Sbjct: 69 RPLAKMAEMARRLHPPSPVPQGVCPAHREPLAAFCGDELRLLCAACERSGEHWAHRVRPL 128
Query: 124 DEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRISTEFSKLHNF 183
+A E + KL KS +L +M+ + Q + W+ ++SQR + EF +L
Sbjct: 129 QDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMVESQRQNVLGEFERLRRL 188
Query: 184 LVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAPTLELLQNPK 243
L EEE LQRL +EE E +L E L Q A L +LI E+ + Q P L LLQ+ K
Sbjct: 189 LAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELEGRCQLPALGLLQDIK 248
Query: 244 EVLTRSEIQDVNY---SLEAVKVKTVCQIPLMKEMLKRFQVAVNLAEDTAHPKLVFSQEG 300
+ L R +QDV + ++++TVC++P + E L+RF+ V L DTA+P+L+ S++
Sbjct: 249 DALRR--VQDVKLQPPEVVPMELRTVCRVPGLVETLRRFRGDVTLDPDTANPELILSEDR 306
Query: 301 RYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHLPCVLGKNVFTSGKHYWEVES 360
R V+ + P +P ERF PCVLG+ FTSG+HYWEVE
Sbjct: 307 RSVQRGDLRQALP------------DSP------ERFDPGPCVLGQERFTSGRHYWEVEV 348
Query: 361 RDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIYWSAAGYWPLIGFPGTPTQQEPALHRV 420
D A+GVCRE+V ++ ++S G W + + Y+ P + P RV
Sbjct: 349 GDRTSWALGVCRENV-NRKEKGELSAGNGFWILVF-LGSYYNSSERALAPLRDPP--RRV 404
Query: 421 GVYLDRGTGNVSFYSAVDGVHLHTFSCSSVS-RLRPFFWLSPLASLVIP 468
G++LD G++SFYSA DG L F S LRP F SPL+S P
Sbjct: 405 GIFLDYEAGHLSFYSATDGSLLFIFPEIPFSGTLRPLF--SPLSSSPTP 451
>gi|112421127 tripartite motif-containing 58 [Homo sapiens]
Length = 486
Score = 300 bits (769), Expect = 1e-81
Identities = 167/474 (35%), Positives = 257/474 (54%), Gaps = 25/474 (5%)
Query: 4 EDIQEELTCPICLDYFQDPVSIECGHNFCRGCL----HRNWAPGGGPFPCPECRHPSAPA 59
E ++E+ CP+CLD+ Q+PVS++CGH+FC C+ ++ GG + CP+CR P P+
Sbjct: 8 ERLREDARCPVCLDFLQEPVSVDCGHSFCLRCISEFCEKSDGAQGGVYACPQCRGPFRPS 67
Query: 60 ALRPNWALARLTEKTQRRRLGPVPPGL-CGRHWEPLRLFCEDDQRPVCLVCRESQEHQTH 118
RPN LA L E +R LG P C RH E L FCE+D+ +C VC EH+TH
Sbjct: 68 GFRPNRQLAGLVESVRRLGLGAGPGARRCARHGEDLSRFCEEDEAALCWVCDAGPEHRTH 127
Query: 119 AMAPIDEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRISTEFS 178
AP+ EA SY+ KL + + +++ + + K WK+K++ QR R EF
Sbjct: 128 RTAPLQEAAGSYQVKLQMALELMRKELEDALTQEANVGKKTVIWKEKVEMQRQRFRLEFE 187
Query: 179 KLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAPTLEL 238
K FL +EE L+RL EE T ++L E+ +L Q +LK+L E+ E+ Q P L L
Sbjct: 188 KHRGFLAQEEQRQLRRLEAEERATLQRLRESKSRLVQQSKALKELADELQERCQRPALGL 247
Query: 239 LQNPKEVLTRSE-IQDVNYSLEAVKVKTVCQIPLMKEMLKRFQVAVNLAEDTAHPKLVFS 297
L+ + VL+RS+ + + +++KT C IP +E+L++FQV V L TAHP L+ +
Sbjct: 248 LEGVRGVLSRSKAVTRLEAENIPMELKTACCIPGRRELLRKFQVDVKLDPATAHPSLLLT 307
Query: 298 QEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHLPCVLGKNVFTSGKHYWE 357
+ R V++ P NP ERF PC+LG F+SG+HYWE
Sbjct: 308 ADLRSVQDGEPWRDVP------------NNP------ERFDTWPCILGLQSFSSGRHYWE 349
Query: 358 VESRDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIYWSAAGYWPLIGFPGTPTQQEPAL 417
V + E +GVC +D + + SP+ G+WA++ + ++ P P Q +
Sbjct: 350 VLVGEGAEWGLGVC-QDTLPRKGETTPSPENGVWALWLLKGNEYMVLASPSVPLLQLESP 408
Query: 418 HRVGVYLDRGTGNVSFYSAVDGVHLHTFSCSSVSRLRPFFWLSPLASLVIPPVT 471
+G++LD G +SFY+ DG +++TF+ LRP+F++ L++PP T
Sbjct: 409 RCIGIFLDYEAGEISFYNVTDGSYIYTFNQLFSGLLRPYFFICDATPLILPPTT 462
>gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens]
Length = 477
Score = 291 bits (746), Expect = 7e-79
Identities = 183/492 (37%), Positives = 264/492 (53%), Gaps = 49/492 (9%)
Query: 3 AEDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGP---------FPCPECR 53
A +QEE TC ICLDYF DPV CGHNFCR C+ +W G FPCPECR
Sbjct: 7 ARKLQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSFPCPECR 66
Query: 54 HPSAPAALRPNWALARLTEKTQRRRLGPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQ 113
S L PN L ++ E Q+ G LC H EPL+LFC+ DQ P+C+VCRES+
Sbjct: 67 EMSPQRNLLPNRLLTKVAEMAQQHP-GLQKQDLCQEHHEPLKLFCQKDQSPICVVCRESR 125
Query: 114 EHQTHAMAPIDEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRI 173
EH+ H + P +EA + Y+ KL + L ++ + +LQ E ++ +W+ K+K +R RI
Sbjct: 126 EHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLAEWQGKVKERRERI 185
Query: 174 STEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQA 233
EF K++ +LVEEE LQ L EEEET +L E+ L++ SL+ L+L++ E+S
Sbjct: 186 VLEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSLELLLLQLEERSTQ 245
Query: 234 PTLELLQNPKEVLTRSEIQDVNYSLEAVKV------KTVCQIPLMKEMLKRFQVAVNLAE 287
L++LQ+ KE L+R N S++ +V +TVC++P E+L+ F V
Sbjct: 246 GPLQMLQDMKEPLSRKN----NVSVQCPEVAPPTRPRTVCRVPGQIEVLRGFLEDVVPDA 301
Query: 288 DTAHPKLVF--SQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHLPCVLG 345
+A+P L+ S++ RY+ ++ S + +RF PC +G
Sbjct: 302 TSAYPYLLLYESRQRRYLGSSPEGSGF-------------------CSKDRFVAYPCAVG 342
Query: 346 KNVFTSGKHYWEVESRDSLEV--AVGVCREDVMGITDRSKMSPDVGIWAIYWSAAGYWPL 403
+ F+SG+HYWEV + + A+GVCR++V DR P+ G W + S +
Sbjct: 343 QTAFSSGRHYWEVGMNITGDALWALGVCRDNV-SRKDRVPKCPENGFWVVQLSKGTKYLS 401
Query: 404 IGFPGTPTQ-QEPALHRVGVYLDRGTGNVSFYSAVDGVHLHTFSCSSV-SRLRPFFWLSP 461
TP EP H +G++LD G VSFYS DG HLHT+S ++ L+PFF L
Sbjct: 402 TFSALTPVMLMEPPSH-MGIFLDFEAGEVSFYSVSDGSHLHTYSQATFPGPLQPFFCLGA 460
Query: 462 LAS--LVIPPVT 471
S +VI VT
Sbjct: 461 PKSGQMVISTVT 472
>gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens]
Length = 477
Score = 291 bits (746), Expect = 7e-79
Identities = 183/492 (37%), Positives = 264/492 (53%), Gaps = 49/492 (9%)
Query: 3 AEDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGP---------FPCPECR 53
A +QEE TC ICLDYF DPV CGHNFCR C+ +W G FPCPECR
Sbjct: 7 ARKLQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSFPCPECR 66
Query: 54 HPSAPAALRPNWALARLTEKTQRRRLGPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQ 113
S L PN L ++ E Q+ G LC H EPL+LFC+ DQ P+C+VCRES+
Sbjct: 67 EMSPQRNLLPNRLLTKVAEMAQQHP-GLQKQDLCQEHHEPLKLFCQKDQSPICVVCRESR 125
Query: 114 EHQTHAMAPIDEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRI 173
EH+ H + P +EA + Y+ KL + L ++ + +LQ E ++ +W+ K+K +R RI
Sbjct: 126 EHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLAEWQGKVKERRERI 185
Query: 174 STEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQA 233
EF K++ +LVEEE LQ L EEEET +L E+ L++ SL+ L+L++ E+S
Sbjct: 186 VLEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSLELLLLQLEERSTQ 245
Query: 234 PTLELLQNPKEVLTRSEIQDVNYSLEAVKV------KTVCQIPLMKEMLKRFQVAVNLAE 287
L++LQ+ KE L+R N S++ +V +TVC++P E+L+ F V
Sbjct: 246 GPLQMLQDMKEPLSRKN----NVSVQCPEVAPPTRPRTVCRVPGQIEVLRGFLEDVVPDA 301
Query: 288 DTAHPKLVF--SQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHLPCVLG 345
+A+P L+ S++ RY+ ++ S + +RF PC +G
Sbjct: 302 TSAYPYLLLYESRQRRYLGSSPEGSGF-------------------CSKDRFVAYPCAVG 342
Query: 346 KNVFTSGKHYWEVESRDSLEV--AVGVCREDVMGITDRSKMSPDVGIWAIYWSAAGYWPL 403
+ F+SG+HYWEV + + A+GVCR++V DR P+ G W + S +
Sbjct: 343 QTAFSSGRHYWEVGMNITGDALWALGVCRDNV-SRKDRVPKCPENGFWVVQLSKGTKYLS 401
Query: 404 IGFPGTPTQ-QEPALHRVGVYLDRGTGNVSFYSAVDGVHLHTFSCSSV-SRLRPFFWLSP 461
TP EP H +G++LD G VSFYS DG HLHT+S ++ L+PFF L
Sbjct: 402 TFSALTPVMLMEPPSH-MGIFLDFEAGEVSFYSVSDGSHLHTYSQATFPGPLQPFFCLGA 460
Query: 462 LAS--LVIPPVT 471
S +VI VT
Sbjct: 461 PKSGQMVISTVT 472
>gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]
Length = 488
Score = 267 bits (682), Expect = 2e-71
Identities = 164/486 (33%), Positives = 240/486 (49%), Gaps = 37/486 (7%)
Query: 4 EDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAALRP 63
E++Q E +C +CL+Y ++PV IECGHNFC+ C+ R W FPCP CR S +LRP
Sbjct: 21 ENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERDFPCPVCRKTSRYRSLRP 80
Query: 64 NWALARLTE-----KTQRRRLGPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQTH 118
N L + E + +R++ LC +H E L LFC +DQ VCL+C S H+ H
Sbjct: 81 NRQLGSMVEIAKQLQAVKRKIRD--ESLCPQHHEALSLFCYEDQEAVCLICAISHTHRAH 138
Query: 119 AMAPIDEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRISTEFS 178
+ P+D+A + Y+EKL K L K++++ + E K + K ++S+R +I EF
Sbjct: 139 TVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVESRRQQILREFE 198
Query: 179 KLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAPTLEL 238
+LH L EE+ + L RL +EE++ ++L EN L L L EV K E+
Sbjct: 199 ELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDLAHLAAEVEGKCLQSGFEM 258
Query: 239 LQNPKEVLTR------SEIQDVNYSLEAVKVKTVCQIPLMKEMLKRFQVAVNLAEDTAHP 292
L++ K L + E+ V+ LE Q ++++LK+ V L +TAHP
Sbjct: 259 LKDVKSTLEKCEKVKTMEVTSVSIELEKNFSNFPRQYFALRKILKQLIADVTLDPETAHP 318
Query: 293 KLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHLPCVLGKNVFTSG 352
LV S++ + VK F R RF PCVL FTSG
Sbjct: 319 NLVLSEDRKSVK-----------------FVETRLRDLPDTPRRFTFYPCVLATEGFTSG 361
Query: 353 KHYWEVESRDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIYWSAAGYWPLIGFPGTPTQ 412
+HYWEVE D AVGVCR+ V + + + P+ G W + + P TP
Sbjct: 362 RHYWEVEVGDKTHWAVGVCRDSVSRKGELTPL-PETGYWRVRLWNGDKYAATTTPFTPLH 420
Query: 413 QEPALHRVGVYLDRGTGNVSFYSAVDGVHLHTFSCSSVSRLRPFFW------LSPLASLV 466
+ RVG++LD G +SFY+ D H++TF+ + +L P F+ A L
Sbjct: 421 IKVKPKRVGIFLDYEAGTLSFYNVTDRSHIYTFTDTFTEKLWPLFYPGIRAGRKNAAPLT 480
Query: 467 IPPVTD 472
I P TD
Sbjct: 481 IRPPTD 486
>gi|15208660 tripartite motif protein 21 [Homo sapiens]
Length = 475
Score = 261 bits (668), Expect = 7e-70
Identities = 173/459 (37%), Positives = 245/459 (53%), Gaps = 33/459 (7%)
Query: 8 EELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAALRPNWAL 67
EE+TCPICLD F +PVSIECGH+FC+ C+ + GG CP CR LRPN L
Sbjct: 12 EEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSV--CPVCRQRFLLKNLRPNRQL 69
Query: 68 AR----LTEKTQRRRLGPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHAMAPI 123
A L E +Q R G C H E L LFCE D + +C VC +S++H+ HAM P+
Sbjct: 70 ANMVNNLKEISQEAREG-TQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVPL 128
Query: 124 DEAFESYREKLLKSQRNLVAKMKKVMHLQ-DVEVKNATQWKDKIKSQRMRISTEFSKLHN 182
+EA + Y+EKL + L K + L+ ++ +K A WK +++Q+ RI EF + N
Sbjct: 129 EEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRA-DWKKTVETQKSRIHAEFVQQKN 187
Query: 183 FLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAPTLELLQNP 242
FLVEEE LQ L K+E E + L E KL Q +L++LI E+ + + LELLQ
Sbjct: 188 FLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQEV 247
Query: 243 KEVLTRSEIQDV-NYSLEAVKVKTVCQIPLMKEMLKRFQVAVNLAEDTAHPKLVFSQEGR 301
VL RSE ++ + + + ++++VC +P +K+ML+ V + L DTA+P L+ S++ R
Sbjct: 248 IIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWLILSEDRR 307
Query: 302 YVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHLPCVLGKNVFTSGKHYWEVESR 361
V+ + S P ERF P VLG F SGKHYWEV+
Sbjct: 308 QVRLGDTQQSIP------------------GNEERFDSYPMVLGAQHFHSGKHYWEVDVT 349
Query: 362 DSLEVAVGVCREDVMGITDRSKMSPDVGIWAIY-WSAAGYWPLIGFPGTPTQQEPALHRV 420
+GVCR+ V +S G W I+ W+ Y +P TP + +V
Sbjct: 350 GKEAWDLGVCRDSVRR-KGHFLLSSKSGFWTIWLWNKQKY-EAGTYPQTPLHLQVPPCQV 407
Query: 421 GVYLDRGTGNVSFYSAVD-GVHLHTFS-CSSVSRLRPFF 457
G++LD G VSFY+ D G +++FS C+ LRPFF
Sbjct: 408 GIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFF 446
>gi|68160935 tripartite motif-containing 17 isoform 2 [Homo sapiens]
Length = 450
Score = 260 bits (665), Expect = 2e-69
Identities = 168/468 (35%), Positives = 248/468 (52%), Gaps = 49/468 (10%)
Query: 27 CGHNFCRGCLHRNWAPGGGP---------FPCPECRHPSAPAALRPNWALARLTEKTQRR 77
CGHNFCR C+ +W G FPCPECR S L PN L ++ E Q+
Sbjct: 4 CGHNFCRACIQLSWEKARGKKGRRKRKGSFPCPECREMSPQRNLLPNRLLTKVAEMAQQH 63
Query: 78 RLGPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHAMAPIDEAFESYREKLLKS 137
G LC H EPL+LFC+ DQ P+C+VCRES+EH+ H + P +EA + Y+ KL +
Sbjct: 64 P-GLQKQDLCQEHHEPLKLFCQKDQSPICVVCRESREHRLHRVLPAEEAVQGYKLKLEED 122
Query: 138 QRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNK 197
L ++ + +LQ E ++ +W+ K+K +R RI EF K++ +LVEEE LQ L
Sbjct: 123 MEYLREQITRTGNLQAREEQSLAEWQGKVKERRERIVLEFEKMNLYLVEEEQRLLQALET 182
Query: 198 EEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAPTLELLQNPKEVLTRSEIQDVNYS 257
EEEET +L E+ L++ SL+ L+L++ E+S L++LQ+ KE L+R N S
Sbjct: 183 EEEETASRLRESVACLDRQGHSLELLLLQLEERSTQGPLQMLQDMKEPLSRKN----NVS 238
Query: 258 LEAVKV------KTVCQIPLMKEMLKRFQVAVNLAEDTAHPKLVF--SQEGRYVKNTASA 309
++ +V +TVC++P E+L+ F V +A+P L+ S++ RY+ ++
Sbjct: 239 VQCPEVAPPTRPRTVCRVPGQIEVLRGFLEDVVPDATSAYPYLLLYESRQRRYLGSSPEG 298
Query: 310 SSWPVFSSAWNYFAGWRNPQKTAFVERFQHLPCVLGKNVFTSGKHYWEVESRDSLEV--A 367
S + +RF PC +G+ F+SG+HYWEV + + A
Sbjct: 299 SGF-------------------CSKDRFVAYPCAVGQTAFSSGRHYWEVGMNITGDALWA 339
Query: 368 VGVCREDVMGITDRSKMSPDVGIWAIYWSAAGYWPLIGFPGTPTQ-QEPALHRVGVYLDR 426
+GVCR++V DR P+ G W + S + TP EP H +G++LD
Sbjct: 340 LGVCRDNV-SRKDRVPKCPENGFWVVQLSKGTKYLSTFSALTPVMLMEPPSH-MGIFLDF 397
Query: 427 GTGNVSFYSAVDGVHLHTFSCSSV-SRLRPFFWLSPLAS--LVIPPVT 471
G VSFYS DG HLHT+S ++ L+PFF L S +VI VT
Sbjct: 398 EAGEVSFYSVSDGSHLHTYSQATFPGPLQPFFCLGAPKSGQMVISTVT 445
>gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]
Length = 518
Score = 257 bits (657), Expect = 1e-68
Identities = 166/516 (32%), Positives = 244/516 (47%), Gaps = 67/516 (12%)
Query: 4 EDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAALRP 63
E++Q E +C +CL+Y ++PV IECGHNFC+ C+ R W FPCP CR S +LRP
Sbjct: 21 ENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERDFPCPVCRKTSRYRSLRP 80
Query: 64 NWALARLTE-----KTQRRRLGPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQTH 118
N L + E + +R++ LC +H E L LFC +DQ VCL+C S H+ H
Sbjct: 81 NRQLGSMVEIAKQLQAVKRKIRD--ESLCPQHHEALSLFCYEDQEAVCLICAISHTHRAH 138
Query: 119 AMAPIDEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRISTEFS 178
+ P+D+A + Y+EKL K L K++++ + E K + K ++S+R +I EF
Sbjct: 139 TVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVESRRQQILREFE 198
Query: 179 KLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAPTLEL 238
+LH L EE+ + L RL +EE++ ++L EN L L L EV K E+
Sbjct: 199 ELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDLAHLAAEVEGKCLQSGFEM 258
Query: 239 LQNPKEVLTRSEIQDVNYSLEAV-------------------KVKTV------------- 266
L++ K L ++ + SL + KVKT+
Sbjct: 259 LKDVKSTLEKNIPRKFGGSLSTICPRDHKALLGLVKEINRCEKVKTMEVTSVSIELEKNF 318
Query: 267 ----CQIPLMKEMLKRFQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYF 322
Q ++++LK+ V L +TAHP LV S++ + VK F
Sbjct: 319 SNFPRQYFALRKILKQLIADVTLDPETAHPNLVLSEDRKSVK-----------------F 361
Query: 323 AGWRNPQKTAFVERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCREDVMGITDRS 382
R RF PCVL FTSG+HYWEVE D AVGVCR+ V + +
Sbjct: 362 VETRLRDLPDTPRRFTFYPCVLATEGFTSGRHYWEVEVGDKTHWAVGVCRDSVSRKGELT 421
Query: 383 KMSPDVGIWAIYWSAAGYWPLIGFPGTPTQQEPALHRVGVYLDRGTGNVSFYSAVDGVHL 442
+ P+ G W + + P TP + RVG++LD G +SFY+ D H+
Sbjct: 422 PL-PETGYWRVRLWNGDKYAATTTPFTPLHIKVKPKRVGIFLDYEAGTLSFYNVTDRSHI 480
Query: 443 HTFSCSSVSRLRPFFW------LSPLASLVIPPVTD 472
+TF+ + +L P F+ A L I P TD
Sbjct: 481 YTFTDTFTEKLWPLFYPGIRAGRKNAAPLTIRPPTD 516
>gi|5730009 ret finger protein [Homo sapiens]
Length = 513
Score = 251 bits (642), Expect = 8e-67
Identities = 168/514 (32%), Positives = 250/514 (48%), Gaps = 72/514 (14%)
Query: 3 AEDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAALR 62
AE +Q+E TCP+CL YF +P+ ++CGHN C CL R W CP+CR +R
Sbjct: 7 AECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTAETNVSCPQCRETFPQRHMR 66
Query: 63 PNWALARLTEKT-QRRRLGPVPP----GLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQT 117
PN LA +T+ Q R P P G+C +H EPL+L+CE+DQ P+C+VC S+EH+
Sbjct: 67 PNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICVVCDRSREHRG 126
Query: 118 HAMAPIDEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKS----QRMRI 173
H++ P++EA E ++E++ +N + +K+V L+ Q + ++ S +R +I
Sbjct: 127 HSVLPLEEAVEGFKEQI----QNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQMEREKI 182
Query: 174 STEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQA 233
EF +L++ L E E L RL + + +N + + I+ L LI ++ EK Q
Sbjct: 183 VWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQQQ 242
Query: 234 PTLELLQNPKEVLTRSE----------IQDVNYSLEAVKVKTVCQIPLMKEMLKRFQ--- 280
PT ELLQ+ + L+R+E D+ + K + +K+ ++ Q
Sbjct: 243 PTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKMQSDM 302
Query: 281 -------------VAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRN 327
V V L DTA+P L+ S R V+ + P N
Sbjct: 303 EKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLP------------DN 350
Query: 328 PQKTAFVERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCREDVM---GITDRSKM 384
P ERF PCVLG F +G+HYWEVE D + +GVC + V G+T
Sbjct: 351 P------ERFNLFPCVLGSPCFIAGRHYWEVEVGDKAKWTIGVCEDSVCRKGGVTS---- 400
Query: 385 SPDVGIWAI-YWSAAGYWPLIGFPGTPTQQEPALHRVGVYLDRGTGNVSFYSAVDGVHLH 443
+P G WA+ W YW L P T L RVG++LD G VSFY+ + H
Sbjct: 401 APQNGFWAVSLWYGKEYWALTS-PMTALPLRTPLQRVGIFLDYDAGEVSFYNVTERCHTF 459
Query: 444 TFS-CSSVSRLRPFFWLS-----PLASLVIPPVT 471
TFS + +RP+F LS A L+I P++
Sbjct: 460 TFSHATFCGPVRPYFSLSYSGGKSAAPLIICPMS 493
>gi|157743261 tripartite motif-containing 75 [Homo sapiens]
Length = 468
Score = 250 bits (638), Expect = 2e-66
Identities = 149/467 (31%), Positives = 238/467 (50%), Gaps = 33/467 (7%)
Query: 6 IQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAALRPNW 65
+Q E C ICLDY DPV+IECGHNFCR C+ ++W FPCP CRH R N
Sbjct: 10 LQAEAKCSICLDYLSDPVTIECGHNFCRSCIQQSWLDLQELFPCPVCRHQCQEGHFRSNT 69
Query: 66 ALARLTE------KTQRRRLGPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHA 119
L R+ E T+ + LC +H +PL +FC++D +C +C + +HQ H
Sbjct: 70 QLGRMIEIAKLLQSTKSNKRKQEETTLCEKHNQPLSVFCKEDLMVLCPLCTQPPDHQGHH 129
Query: 120 MAPIDEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRISTEFSK 179
+ PI++A YR++ + L ++ + L + K + ++ +++QR +S+EF
Sbjct: 130 VRPIEKAAIHYRKRFCSYIQPLKKQLADLQKLISTQSKKPLELREMVENQRQELSSEFEH 189
Query: 180 LHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAPTLELL 239
L+ FL E+ L RL +EE++ ++KL+ N + A+LK + +V E S+ LELL
Sbjct: 190 LNQFLDREQQAVLSRLAEEEKDNQQKLSANITAFSNYSATLKSQLSKVVELSELSELELL 249
Query: 240 QNPKEVLTRSEIQDVNYSLEAVKVK-TVCQIP----LMKEMLKRFQVAVNLAEDTAHPKL 294
K + SE + + S+ ++ +K C P ++ ++K+F+V + L +TAHP L
Sbjct: 250 SQIK-IFYESE-NESSPSIFSIHLKRDGCSFPPQYSALQRIIKKFKVEIILDPETAHPNL 307
Query: 295 VFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHLPCVLGKNVFTSGKH 354
+ S++ + V+ T R + F +RF P VLG F SG+H
Sbjct: 308 IVSEDKKRVRFTK------------------RKQKVPGFPKRFTVKPVVLGFPYFHSGRH 349
Query: 355 YWEVESRDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIYWSAAGYWPLIGFPGTPTQQE 414
+WE+E D E A+G+C+ D + R S W I GY FP TP E
Sbjct: 350 FWEIEVGDKSEWAIGICK-DSLPTKARRPSSAQQECWRIELQDDGYHAPGAFP-TPLLLE 407
Query: 415 PALHRVGVYLDRGTGNVSFYSAVDGVHLHTFSCSSVSRLRPFFWLSP 461
+G++LD G +SFY+ + H+ TF+ + LRP+F++ P
Sbjct: 408 VKARAIGIFLDYEMGEISFYNMAEKSHICTFTDTFTGPLRPYFYVGP 454
>gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens]
Length = 511
Score = 248 bits (633), Expect = 9e-66
Identities = 167/505 (33%), Positives = 247/505 (48%), Gaps = 76/505 (15%)
Query: 3 AEDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWA-PGGG-----------PFPCP 50
A ++Q E TC ICL+ F++PVS+ECGH+FCR C+ R W PG G P PCP
Sbjct: 20 AAELQGEATCSICLELFREPVSVECGHSFCRACIGRCWERPGAGSVGAATRAPPFPLPCP 79
Query: 51 ECRHPSAPAALRPNWALARLTEKTQRRRLGPVPPG--------------LCGRHWEPLRL 96
+CR P+ P+ LRPN LA + +R L PG CG+H EP +L
Sbjct: 80 QCREPARPSQLRPNRQLAAVATLLRRFSLPAAAPGEHGSQAAAARAAAARCGQHGEPFKL 139
Query: 97 FCEDDQRPVCLVCRESQEHQTHAMAPIDEAFESYREKLLKSQRNLVAKMKKVMHLQDVEV 156
+C+DD R +C+VC ++EH+ HA+ P+DEA + +E L R L +++ + E
Sbjct: 140 YCQDDGRAICVVCDRAREHREHAVLPLDEAVQEAKELLESRLRVLKKELEDCEVFRSTEK 199
Query: 157 KNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQT 216
K + + ++ +++ ++ EF L FLVE+E L RL + E +K NEN +L
Sbjct: 200 KESKELLKQMAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQLGVE 259
Query: 217 IASLKKLILEVGEKSQAPTLELLQNPKEVLTR-------------SEIQDV--NYSLEAV 261
I L KL ++ E +Q P L+ LQ K L+R SE+++ N SL+
Sbjct: 260 ITQLSKLSSQIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNVSLKTF 319
Query: 262 KVKTVC---QIPLMKEMLKRFQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSA 318
+K + + L E+ K +V + L DTA+P+L+ S + + V+ A P
Sbjct: 320 VLKGMLKKFKEDLRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQDLPNHPC- 378
Query: 319 WNYFAGWRNPQKTAFVERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCREDV--M 376
RF VL F+SG+H+WEVE A GV RE V
Sbjct: 379 -----------------RFDTNTRVLASCGFSSGRHHWEVEVGSKDGWAFGVARESVRRK 421
Query: 377 GITDRSKMSPDVGIWAIYWSAAGYWPLIGFPGTPTQQEPA----LHRVGVYLDRGTGNVS 432
G+T +P+ G+WA+ + YW + T ++ P L RV V LD G VS
Sbjct: 422 GLT---PFTPEEGVWALQLNGGQYWAV-----TSPERSPLSCGHLSRVRVALDLEVGAVS 473
Query: 433 FYSAVDGVHLHTFSCSSVSRLRPFF 457
FY+ D HL+TF + R+ P F
Sbjct: 474 FYAVEDMRHLYTFRVNFQERVFPLF 498
>gi|37622899 ring finger protein 137 [Homo sapiens]
Length = 485
Score = 243 bits (621), Expect = 2e-64
Identities = 163/496 (32%), Positives = 254/496 (51%), Gaps = 69/496 (13%)
Query: 4 EDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWA-PGGGP---FPCPECRHPSAPA 59
E I EE+ CPIC+ + ++P+SI+CGH+FC CL W PG + CP CR P P
Sbjct: 8 EAIVEEVACPICMTFLREPMSIDCGHSFCHSCLSGLWEIPGESQNWGYTCPLCRAPVQPR 67
Query: 60 ALRPNWALARLTEKTQRRRLGP---VPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQ 116
LRPNW LA + EK + RL P + LC RH E L++FC++D +C C +S EH+
Sbjct: 68 NLRPNWQLANVVEKVRLLRLHPGMGLKGDLCERHGEKLKMFCKEDVLIMCEACSQSPEHE 127
Query: 117 THAMAPIDEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRISTE 176
H++ P+++ Y+ +L ++ +L + ++ L+ E K WK ++++++ I E
Sbjct: 128 AHSVVPMEDVAWEYKWELHEALEHLKKEQEEAWKLEVGERKRTATWKIQVETRKQSIVWE 187
Query: 177 FSKL----------HNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILE 226
F K H L E L L +E ET +KL N +L Q L ++I E
Sbjct: 188 FEKYQRLLEKKQPPHRQLGAEVAAALASLQREAAETMQKLELNHSELIQQSQVLWRMIAE 247
Query: 227 VGEKSQAPTLELLQNPKEVLTRSEIQDVNYSLE-----AVKVKTVCQIPLMKEMLKRFQV 281
+ E+SQ P +LQ+ +EVL RS+ ++SL+ ++++KT C++ ++E+LK +
Sbjct: 248 LKERSQRPVRWMLQDIQEVLNRSK----SWSLQQPEPISLELKTDCRVLGLREILKTYAA 303
Query: 282 AVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHLP 341
V L DTA+ +L+ S++ + V + P NP ERF
Sbjct: 304 DVRLDPDTAYSRLIVSEDRKRVHYGDTNQKLP------------DNP------ERFYRYN 345
Query: 342 CVLGKNVFTSGKHYWEVESRDSLEVAVGVCREDVMGITDRSK---MSPDVGIWAI----- 393
VLG +SG+HYWEVE D E +GVC+++V DR + +SP G W I
Sbjct: 346 IVLGSQCISSGRHYWEVEVGDRSEWGLGVCKQNV----DRKEVVYLSPHYGFWVIRLRKG 401
Query: 394 --YWSAAGYWPLIGFPGTPTQQEPALHRVGVYLDRGTGNVSFYSAVD-GVHLHTF-SCSS 449
Y + +P++ P P RVG+++D ++SFY+ D G H+ TF
Sbjct: 402 NEYRAGTDEYPILSLPVPP-------RRVGIFVDYEAHDISFYNVTDCGSHIFTFPRYPF 454
Query: 450 VSRLRPFFWLSPLASL 465
RL P+F SP S+
Sbjct: 455 PGRLLPYF--SPCYSI 468
>gi|5454014 tripartite motif-containing 38 [Homo sapiens]
Length = 465
Score = 234 bits (597), Expect = 1e-61
Identities = 161/481 (33%), Positives = 232/481 (48%), Gaps = 39/481 (8%)
Query: 6 IQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGP------FPCPECRHPSAPA 59
+ EE TC ICL +PVSI CGH++C C+ + F CP+CR P
Sbjct: 10 MMEEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQETFCCPQCRAPFHMD 69
Query: 60 ALRPNWALARLTEKTQRRRLGPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHA 119
+LRPN L L E + C H E LFCED+ + +C C + +H+ H
Sbjct: 70 SLRPNKQLGSLIEALKETD----QEMSCEEHGEQFHLFCEDEGQLICWRCERAPQHKGHT 125
Query: 120 MAPIDEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRISTEFSK 179
A +++ + Y+EKL K+ L + + T+WK+K++ QR +I ++F
Sbjct: 126 TALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRITKWKEKVQIQRQKIRSDFKN 185
Query: 180 LHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAPTLELL 239
L FL EEE +L RL KEE++T +L + L LK ILE+ EK Q +LL
Sbjct: 186 LQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHILELEEKCQGSAQKLL 245
Query: 240 QNPKEVLTRSEIQDVNYSLEAVKVK--TVCQIPLM----KEMLKRFQVAVNLAEDTAHPK 293
QN + L+RS + S EAV ++ T+C + + K+ML+ QV+V L DTAH +
Sbjct: 246 QNVNDTLSRSWAVKLETS-EAVSLELHTMCNVSKLYFDVKKMLRSHQVSVTLDPDTAHHE 304
Query: 294 LVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHLPCVLGKNVFTSGK 353
L+ S++ R V G+ + RF PCVLG FTSG+
Sbjct: 305 LILSEDRRQVTR------------------GYTQENQDTSSRRFTAFPCVLGCEGFTSGR 346
Query: 354 HYWEVESRDSLEVAVGVCREDVMGITDRSKMSPDVGIWAI-YWSAAGYWPLIGFPGTPTQ 412
Y+EV+ + +GVC E+V T K P G W + GY L P +
Sbjct: 347 RYFEVDVGEGTGWDLGVCMENVQRGTG-MKQEPQSGFWTLRLCKKKGYVALTSPPTSLHL 405
Query: 413 QEPALHRVGVYLDRGTGNVSFYSAVDGVHLHTFSCSSVS-RLRPFFWLSPLASLVIPPVT 471
E L VG++LD G VSFY+ G H+ TF +S S LRP+F + + L +PP
Sbjct: 406 HEQPL-LVGIFLDYEAGVVSFYNGNTGCHIFTFPKASFSDTLRPYFQVYQYSPLFLPPPG 464
Query: 472 D 472
D
Sbjct: 465 D 465
>gi|198442878 tripartite motif-containing 17 isoform 3 [Homo
sapiens]
Length = 343
Score = 219 bits (559), Expect = 3e-57
Identities = 119/292 (40%), Positives = 170/292 (58%), Gaps = 20/292 (6%)
Query: 3 AEDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGP---------FPCPECR 53
A +QEE TC ICLDYF DPV CGHNFCR C+ +W G FPCPECR
Sbjct: 7 ARKLQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSFPCPECR 66
Query: 54 HPSAPAALRPNWALARLTEKTQRRRLGPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQ 113
S L PN L ++ E Q+ G LC H EPL+LFC+ DQ P+C+VCRES+
Sbjct: 67 EMSPQRNLLPNRLLTKVAEMAQQHP-GLQKQDLCQEHHEPLKLFCQKDQSPICVVCRESR 125
Query: 114 EHQTHAMAPIDEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRI 173
EH+ H + P +EA + Y+ KL + L ++ + +LQ E ++ +W+ K+K +R RI
Sbjct: 126 EHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLAEWQGKVKERRERI 185
Query: 174 STEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQA 233
EF K++ +LVEEE LQ L EEEET +L E+ L++ SL+ L+L++ E+S
Sbjct: 186 VLEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSLELLLLQLEERSTQ 245
Query: 234 PTLELLQNPKEVLTRSEIQDVNYSLEAVKV------KTVCQIPLMKEMLKRF 279
L++LQ+ KE L+R N S++ +V +TVC++P E+L+ F
Sbjct: 246 GPLQMLQDMKEPLSRKN----NVSVQCPEVAPPTRPRTVCRVPGQIEVLRGF 293
>gi|20270353 tripartite motif-containing 43 [Homo sapiens]
Length = 446
Score = 218 bits (554), Expect = 1e-56
Identities = 145/461 (31%), Positives = 222/461 (48%), Gaps = 37/461 (8%)
Query: 7 QEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAALRPNWA 66
Q+ELTC ICL+Y DPV+I CGH+FCR CL +W P CP CR PS + N
Sbjct: 10 QKELTCVICLNYLVDPVTICCGHSFCRPCLCLSWEEAQSPANCPACREPSPKMDFKTNIL 69
Query: 67 LARLTEKTQRRRLGPVPPG---LCGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHAMAPI 123
L L ++ L +CG H + ++FC+ D+ +CL+C SQEH H PI
Sbjct: 70 LKNLVTIARKASLWQFLSSEKQICGTHRQTKKMFCDMDKSLLCLLCSNSQEHGAHKHHPI 129
Query: 124 DEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRISTEFSKLHNF 183
+EA E +REKLLK R L K+++ E + A W+ + + I E+ KLH
Sbjct: 130 EEAAEEHREKLLKQMRILWKKIQENQRNLYEEGRTAFLWRGNVVLRAQMIRNEYRKLHPV 189
Query: 184 LVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAPTLELLQNPK 243
L +EE L+RLNKE +E ++L + +K++Q LK++ E+ E P +ELLQ+
Sbjct: 190 LHKEEKQHLERLNKEYQEIFQQLQRSWVKMDQKSKHLKEMYQELMEMCHKPDVELLQDLG 249
Query: 244 EVLTRSEIQDVNYSLEAVKVKTVCQIPLMKEMLKRFQVAVNLAEDTAHPKLVFSQEGRYV 303
+++ RSE ++ T I + L RF+V ++ + + + ++ R
Sbjct: 250 DIVARSESVLLHMPQPVNPELTAGPITGLVYRLNRFRVEISFHFEVTNHNIRLFEDVR-- 307
Query: 304 KNTASASSW-----PVFSSAWNYFAGWRNPQKTAFVERFQHLPCVLGKNVFTSGKHYWEV 358
SW P+ S +YFA W G VF+ GKHYWE+
Sbjct: 308 -------SWMFRRGPLNSDRSDYFAAW-------------------GARVFSFGKHYWEL 341
Query: 359 ESRDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIYWSAAGYWPLIGFPGTPTQQEPALH 418
+ +S + A+GVC + S D+ + + L P P E L
Sbjct: 342 DVDNSCDWALGVCNNSWIRKNSTMVNSEDIFLLLCLKVDNHFNLLTTSPVFPHYIEKPLG 401
Query: 419 RVGVYLDRGTGNVSFYSAVDGVHLHTFSCSSVS-RLRPFFW 458
RVGV+LD +G+VSF + + ++ S++ +RPFF+
Sbjct: 402 RVGVFLDFESGSVSFLNVTKSSLIWSYPAGSLTFPVRPFFY 442
>gi|22749269 ring finger protein 129 [Homo sapiens]
Length = 471
Score = 217 bits (553), Expect = 2e-56
Identities = 152/471 (32%), Positives = 242/471 (51%), Gaps = 43/471 (9%)
Query: 5 DIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAALRPN 64
++QEE +CPICL+Y +DPV+I CGHNFCR CL +W FPCP CR + R N
Sbjct: 9 NLQEESSCPICLEYLKDPVTINCGHNFCRSCLSVSWKDLDDTFPCPVCRFCFPYKSFRRN 68
Query: 65 WALARLTEKTQR------RRLGPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQTH 118
L LTE ++ +R +C +H + L LFC D +C C S +HQ H
Sbjct: 69 PQLRNLTEIAKQLQIRRSKRKRQKENAMCEKHNQFLTLFCVKDLEILCTQCSFSTKHQKH 128
Query: 119 AMAPIDEAFESYREKL---LKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRIST 175
+ PI +A +RE L L+ RN + +++KV+ LQ + + K K++ +R I++
Sbjct: 129 YICPIKKAASYHREILEGSLEPLRNNIERVEKVIILQG---SKSVELKKKVEYKREEINS 185
Query: 176 EFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAPT 235
EF ++ FL E+++ L+++ EE KLNEN ++L+ +++LK L+ EV KS
Sbjct: 186 EFEQIRLFLQNEQEMILRQIQDEEMNILAKLNENLVELSDYVSTLKHLLREVEGKSVQSN 245
Query: 236 LELLQNPKEVLTRSE----IQDVNYSLEAVKVKTVCQIPLMKEMLKRFQVAVNLAEDTAH 291
LELL K + + + + ++ L Q + ++K FQV V L +TAH
Sbjct: 246 LELLTQAKSMHHKYQNLKCPELFSFRLTKYGFSLPPQYSGLDRIIKPFQVDVILDLNTAH 305
Query: 292 PKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAF-VERFQHLPCVLGKNVFT 350
P+L+ S++ + V+ R + + RF P VLG F+
Sbjct: 306 PQLLVSEDRKAVRYE-------------------RKKRNICYDPRRFYVCPAVLGSQRFS 346
Query: 351 SGKHYWEVESRDSLEVAVGVCREDVMGITDRSKMSPDVGIWAI-YWSAAGYWPLIGFPGT 409
SG+HYWEVE + + +GVC +D + + + S G WAI + +GY + P T
Sbjct: 347 SGRHYWEVEVGNKPKWILGVC-QDCLLRNWQDQPSVLGGFWAIGRYMKSGY--VASGPKT 403
Query: 410 PTQQEPAL--HRVGVYLDRGTGNVSFYSAVDGVHLHTFSCSSVSRLRPFFW 458
TQ P + ++G++LD G++SFY+ D L+TF+ + P+F+
Sbjct: 404 -TQLLPVVKPSKIGIFLDYELGDLSFYNMNDRSILYTFNDCFTEAVWPYFY 453
>gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens]
Length = 488
Score = 214 bits (546), Expect = 1e-55
Identities = 148/475 (31%), Positives = 235/475 (49%), Gaps = 55/475 (11%)
Query: 5 DIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPG----GGPFPCPECRHPSAPAA 60
DI+EE+TCPICL+ +P+SI+CGH+FC+ C+ N G CP C+ P
Sbjct: 8 DIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQPGN 67
Query: 61 LRPNWALARLTEKTQRRRLGP---VPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQT 117
LRPN LA + + + LGP + LC H E L+LFC++D + +C +C SQEH+
Sbjct: 68 LRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRG 127
Query: 118 HAMAPIDEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRISTEF 177
H ++E + Y+EK +S + L + ++ L + T WK++++ +R RI TEF
Sbjct: 128 HHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEF 187
Query: 178 SKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAPTLE 237
++L N L E L++L +EE++ + + E L SL++LI ++ + Q T+E
Sbjct: 188 NQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQGSTME 247
Query: 238 LLQNPKEVLTRSEIQDVNYSLEAV--KVKTVCQIPLMKEMLK---------RFQVAVNLA 286
LLQ+ +V RSE + EA+ K++++ + P +K ML+ + V V L
Sbjct: 248 LLQDVSDVTERSEFWTLR-KPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYWVDVTLN 306
Query: 287 EDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHLPC-VLG 345
TA+ LV ++ R V+ + S P + +E+ H C VLG
Sbjct: 307 PHTANLNLVLAKNRRQVRFVGAKVSGP------------------SCLEK--HYDCSVLG 346
Query: 346 KNVFTSGKHYWEVESRDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIYWSAAGYWPLIG 405
F+SGKHYWEV+ +GVC + + + + ++ Y +GYW +IG
Sbjct: 347 SQHFSSGKHYWEVDVAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYW-VIG 405
Query: 406 F-------------PGTPTQQEPALHRVGVYLDRGTGNVSFYSAVD-GVHLHTFS 446
P RVGV+LD G VSFY+ + G ++TFS
Sbjct: 406 LQHNHEYRAYEDSSPSLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFS 460
>gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens]
Length = 516
Score = 214 bits (546), Expect = 1e-55
Identities = 148/475 (31%), Positives = 235/475 (49%), Gaps = 55/475 (11%)
Query: 5 DIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPG----GGPFPCPECRHPSAPAA 60
DI+EE+TCPICL+ +P+SI+CGH+FC+ C+ N G CP C+ P
Sbjct: 36 DIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQPGN 95
Query: 61 LRPNWALARLTEKTQRRRLGP---VPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQT 117
LRPN LA + + + LGP + LC H E L+LFC++D + +C +C SQEH+
Sbjct: 96 LRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRG 155
Query: 118 HAMAPIDEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRISTEF 177
H ++E + Y+EK +S + L + ++ L + T WK++++ +R RI TEF
Sbjct: 156 HHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEF 215
Query: 178 SKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAPTLE 237
++L N L E L++L +EE++ + + E L SL++LI ++ + Q T+E
Sbjct: 216 NQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQGSTME 275
Query: 238 LLQNPKEVLTRSEIQDVNYSLEAV--KVKTVCQIPLMKEMLK---------RFQVAVNLA 286
LLQ+ +V RSE + EA+ K++++ + P +K ML+ + V V L
Sbjct: 276 LLQDVSDVTERSEFWTLR-KPEALPTKLRSMFRAPDLKRMLRVCRELTDVQSYWVDVTLN 334
Query: 287 EDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHLPC-VLG 345
TA+ LV ++ R V+ + S P + +E+ H C VLG
Sbjct: 335 PHTANLNLVLAKNRRQVRFVGAKVSGP------------------SCLEK--HYDCSVLG 374
Query: 346 KNVFTSGKHYWEVESRDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIYWSAAGYWPLIG 405
F+SGKHYWEV+ +GVC + + + + ++ Y +GYW +IG
Sbjct: 375 SQHFSSGKHYWEVDVAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYW-VIG 433
Query: 406 F-------------PGTPTQQEPALHRVGVYLDRGTGNVSFYSAVD-GVHLHTFS 446
P RVGV+LD G VSFY+ + G ++TFS
Sbjct: 434 LQHNHEYRAYEDSSPSLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFS 488
>gi|31542779 tripartite motif family-like 1 [Homo sapiens]
Length = 468
Score = 214 bits (546), Expect = 1e-55
Identities = 146/459 (31%), Positives = 220/459 (47%), Gaps = 26/459 (5%)
Query: 4 EDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAALRP 63
E+++EELTC ICLDYF PV+ ECGH+FC CL R+W P CPEC +
Sbjct: 8 ENLREELTCFICLDYFSSPVTTECGHSFCLVCLLRSWEEHNTPLSCPECWRTLEGPHFQS 67
Query: 64 NWALARLTEKTQRRRLGPVPP----GLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHA 119
N L RL ++ R + G GR + +D+Q V + ++ H
Sbjct: 68 NERLGRLASIARQLRSQVLQSEDEQGSYGRMPTTAKALSDDEQGGSAFVAQSHGANRVHL 127
Query: 120 MAPIDEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRISTEFSK 179
+ EA E +REKL + L + K+ + E + +++ K+ + + +E+ K
Sbjct: 128 SS---EAEEHHREKLQEILNLLRVRRKEAQAVLTHEKERVKLCQEETKTCKQVVVSEYMK 184
Query: 180 LHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAPTLELL 239
+H FL EEE L LQ L +EE+E +KL N +KL Q I SL K+I ++ SQ+ E L
Sbjct: 185 MHQFLKEEEQLQLQLLEQEEKENMRKLRNNEIKLTQQIRSLSKMIAQIESSSQSSAFESL 244
Query: 240 QNPKEVLTRSEIQDVNYSLEAVKVKTVCQIPLMKEMLKRFQVAVNLAEDTAHPKLVFSQE 299
+ + L RSE + ++C+I MKEML++F + L TA+ LV S++
Sbjct: 245 EEVRGALERSEPLLLQCPEATTTELSLCRITGMKEMLRKFSTEITLDPATANAYLVLSED 304
Query: 300 GRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHLPCVLGKNVFTSGKHYWEVE 359
+ VK S P NP ERF VLG +FTSG+HYWEVE
Sbjct: 305 LKSVKYGGSRQQLP------------DNP------ERFDQSATVLGTQIFTSGRHYWEVE 346
Query: 360 SRDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIYWSAAGYWPLIGFPGTPTQQEPALHR 419
+ E VG+C++ V + K D+ Y + P + +
Sbjct: 347 VGNKTEWEVGICKDSVSRKGNLPKPPGDLFSLIGLKIGDDYSLWVSSPLKGQHVREPVCK 406
Query: 420 VGVYLDRGTGNVSFYSAVDGVHLHTFSCSSVSR-LRPFF 457
VGV+LD +G+++FY+ D +++F +S LRP F
Sbjct: 407 VGVFLDYESGHIAFYNGTDESLIYSFPQASFQEALRPIF 445
>gi|157426898 tripartite motif-containing 10 isoform 1 [Homo
sapiens]
Length = 481
Score = 211 bits (536), Expect = 2e-54
Identities = 143/481 (29%), Positives = 229/481 (47%), Gaps = 47/481 (9%)
Query: 6 IQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFP----CPECRHPSAPAAL 61
+ +E+ CPIC ++PV+I+CGHNFCR CL R G CP C+ P P +
Sbjct: 10 LADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLCKEPFRPGSF 69
Query: 62 RPNWALARLTEKTQRRRL----GPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQT 117
RPNW LA + E +R +L G +C H E + FCEDD+ +C+VCRE+ EH T
Sbjct: 70 RPNWQLANVVENIERLQLVSTLGLGEEDVCQEHGEKIYFFCEDDEMQLCVVCREAGEHAT 129
Query: 118 HAMAPIDEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRISTEF 177
H M +++A YRE++ K + L + +++ +Q E K ++ ++R ++ +EF
Sbjct: 130 HTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQVLLTQVSTKRQQVISEF 189
Query: 178 SKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAPTLE 237
+ L FL E++ + L +L ++ + ++ +E L + I LI E+ EK++ P E
Sbjct: 190 AHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFSALIEELEEKNERPARE 249
Query: 238 LLQNPKEVLTRSEIQDVNYSL-------EAVKVKTVCQIPLMKEM----------LKRFQ 280
LL + + L R E + + + ++ +PL +EM L
Sbjct: 250 LLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPLQREMKMFLEKLCFELDYEP 309
Query: 281 VAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHL 340
++L T+HPKL+ S++ + + FS W NPQ RF
Sbjct: 310 AHISLDPQTSHPKLLLSEDHQRAQ----------FSYKWQNSPD--NPQ------RFDRA 351
Query: 341 PCVLGKNVFTSGKHYW--EVESRDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIYWSAA 398
CVL T G+H W ++ VGV EDV ++ P+ G+WA+ +
Sbjct: 352 TCVLAHTGITGGRHTWVVSIDLAHGGSCTVGVVSEDVQR-KGELRLRPEEGVWAVRLAWG 410
Query: 399 GYWPLIGFPGTPTQQEPALHRVGVYLDRGTGNVSFYSAVDGVHLHTFSCSSVSRLRPFFW 458
L FP T +E +V V LD G V+F +AV ++TF+ S ++ PFF
Sbjct: 411 FVSALGSFPTRLTLKEQP-RQVRVSLDYEVGWVTFTNAVTREPIYTFTASFTRKVIPFFG 469
Query: 459 L 459
L
Sbjct: 470 L 470
>gi|88953346 PREDICTED: Tripartite motif-containing protein 43-like
protein 1 [Homo sapiens]
Length = 446
Score = 210 bits (535), Expect = 2e-54
Identities = 144/461 (31%), Positives = 220/461 (47%), Gaps = 37/461 (8%)
Query: 7 QEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAALRPNWA 66
Q+ELTC ICL+Y DPV+I CGH+FCR CL +W P CP CR PS + N
Sbjct: 10 QKELTCVICLNYLVDPVTICCGHSFCRPCLCLSWEEAQSPANCPACREPSPKMDFKTNIL 69
Query: 67 LARLTEKTQRRRLGPVPPG---LCGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHAMAPI 123
L L ++ L +CG H + ++FC+ D+ +CL+C SQEH H PI
Sbjct: 70 LKNLVTIARKASLWQFLSSEKQICGTHRQTKKMFCDMDKSLLCLLCSNSQEHGAHKHYPI 129
Query: 124 DEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRISTEFSKLHNF 183
+EA E REKLLK R L K+++ E + A + + + I E+ KLH
Sbjct: 130 EEAAEEDREKLLKQMRILWKKIQENQRNLYEERRTAFLLRGDVVLRAQMIRNEYRKLHPV 189
Query: 184 LVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAPTLELLQNPK 243
L +EE L+RLNKE +E ++L + +K++Q LK++ E+ E P +ELLQ+
Sbjct: 190 LHKEEKQHLERLNKEYQEIFQQLQRSWVKMDQKSKHLKEMYQELMEMCHKPEVELLQDLG 249
Query: 244 EVLTRSEIQDVNYSLEAVKVKTVCQIPLMKEMLKRFQVAVNLAEDTAHPKLVFSQEGRYV 303
+++ RSE ++ T I + L RF+V ++ + + + ++ R
Sbjct: 250 DIVARSESVLLHMPQPVNPELTAGPITGLVYRLNRFRVEISFHFEVTNHNIRLFEDVR-- 307
Query: 304 KNTASASSW-----PVFSSAWNYFAGWRNPQKTAFVERFQHLPCVLGKNVFTSGKHYWEV 358
SW P+ S +YFA W G VF+ GKHYWE+
Sbjct: 308 -------SWMFRRGPLNSDRSDYFAAW-------------------GARVFSFGKHYWEL 341
Query: 359 ESRDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIYWSAAGYWPLIGFPGTPTQQEPALH 418
+ +S + A+GVC + S D+ + + L P P E L
Sbjct: 342 DVDNSCDWALGVCNNSWIRKNSTMVNSEDIFLLLCLKVDNHFNLLTTSPVFPHYIEKPLG 401
Query: 419 RVGVYLDRGTGNVSFYSAVDGVHLHTFSCSSVS-RLRPFFW 458
RVGV+LD +G+VSF + + ++ S++ +RPFF+
Sbjct: 402 RVGVFLDFESGSVSFLNVTKSSLIWSYPAGSLTFPVRPFFY 442
>gi|210147600 tripartite motif-containing 64 [Homo sapiens]
Length = 449
Score = 199 bits (505), Expect = 6e-51
Identities = 143/464 (30%), Positives = 218/464 (46%), Gaps = 27/464 (5%)
Query: 1 MEAEDIQ---EELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSA 57
M+++D+Q EL C IC++YF DPV+I+CGH+FCR CL G P CP CR S
Sbjct: 1 MDSDDLQVFQNELICCICVNYFIDPVTIDCGHSFCRPCLCLCSEEGRAPMRCPSCRKISE 60
Query: 58 PAALRPNWALARLTEKTQRRRLGPV--PPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEH 115
N L +L+ ++ R + +C H E LFCE D+R +C C ES EH
Sbjct: 61 KPNFNTNVVLKKLSSLARQTRPQNINSSDNICVLHEETKELFCEADKRLLCGPCSESPEH 120
Query: 116 QTHAMAPIDEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRIST 175
H+ +PI A E REKL+K L ++ + + E + KD + ++ I+
Sbjct: 121 MAHSHSPIGWAAEECREKLIKEMDYLWEINQETRNNLNQETRTFHSLKDYVSVRKRIITI 180
Query: 176 EFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAPT 235
++ K+ FL EEE LQ L +E EE ++L ++ +++ Q + +K + E+ E P
Sbjct: 181 QYQKMPIFLDEEEQRHLQALEREAEELFQQLQDSQVRMTQHLERMKDMYRELWETCHVPD 240
Query: 236 LELLQNPKEVLTRSEIQDVNYSLEAVKVKTVCQIPLMKEMLKRFQVAVNLAEDTAHPKLV 295
+ELLQ+ + V R+++ + T I + +ML F+V L+ + +
Sbjct: 241 VELLQDVRNVSARTDLAQMQKPQPVNPELTSWCITGVLDMLNNFRVDSALSTEMIPCYIS 300
Query: 296 FSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHLPCVLGKNVFTSGKHY 355
S++ RYV S P + FA W G FTSGKHY
Sbjct: 301 LSEDVRYVIFGDDHLSAPTDPQGVDSFAVW-------------------GAQAFTSGKHY 341
Query: 356 WEVESRDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIYWSAAGYWPL-IGFPGTPTQQE 414
WEV+ S +GVC +D + D + I + ++ L P +
Sbjct: 342 WEVDVTLSSNWILGVC-QDSRTADANFVIDSDERFFLISSKRSNHYSLSTNSPPLIQYVQ 400
Query: 415 PALHRVGVYLDRGTGNVSFYSAVDGVHLHTFSCSSVSR-LRPFF 457
L +VGV+LD G+VSF+ G ++ F SS S LRPFF
Sbjct: 401 RPLGQVGVFLDYDNGSVSFFDVSKGSLIYGFPPSSFSSPLRPFF 444
>gi|169202375 PREDICTED: tripartite motif-containing protein
64B-like [Homo sapiens]
Length = 449
Score = 199 bits (505), Expect = 6e-51
Identities = 144/464 (31%), Positives = 216/464 (46%), Gaps = 27/464 (5%)
Query: 1 MEAEDIQ---EELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSA 57
M+++D+Q EL C IC++YF DPV+I+CGH+FCR CL G P CP CR S
Sbjct: 1 MDSDDLQVFQNELICCICVNYFIDPVTIDCGHSFCRPCLCLCSEEGRAPMRCPSCRKTSE 60
Query: 58 PAALRPNWALARLTEKTQRRRLGPV--PPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEH 115
N L +L+ ++ R + +C H E LFCE D+R +C C ES EH
Sbjct: 61 KPNFNTNLVLKKLSSLARQTRPQNINSSDNICVLHEETKELFCEADKRLLCGPCSESPEH 120
Query: 116 QTHAMAPIDEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRIST 175
H+ +PI A E REKL+K L ++ + + E KD + ++ I+
Sbjct: 121 MAHSHSPIGWAAEECREKLIKEMDYLWEINQETRNNLNQETSTFHSLKDYVSVRKRIITI 180
Query: 176 EFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAPT 235
++ K+ FL EEE LQ L +E EE ++L ++ +++ Q + +K + E+ E P
Sbjct: 181 QYQKMPIFLDEEEQRHLQALEREAEELFQQLQDSQVRMTQHLERMKDMYRELWETCHMPD 240
Query: 236 LELLQNPKEVLTRSEIQDVNYSLEAVKVKTVCQIPLMKEMLKRFQVAVNLAEDTAHPKLV 295
+ LLQ+ + V R+++ + T I + +ML F+V L+ + +
Sbjct: 241 VVLLQDVRNVSARTDLAQMQKPQPVNPELTSWCITGVLDMLNNFRVDSALSTEMIPCYIS 300
Query: 296 FSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHLPCVLGKNVFTSGKHY 355
S++ RYV S P + FA W G FTSGKHY
Sbjct: 301 LSEDVRYVIFGDDHLSAPTDPQGVDSFAVW-------------------GAQAFTSGKHY 341
Query: 356 WEVESRDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIYWSAAGYWPL-IGFPGTPTQQE 414
WEV+ S +GVCR D + D + I + ++ L P +
Sbjct: 342 WEVDVTLSSNWILGVCR-DSRTADANFVIDSDERFFLISSKRSNHYSLSTNSPPLIQYVQ 400
Query: 415 PALHRVGVYLDRGTGNVSFYSAVDGVHLHTFSCSSVSR-LRPFF 457
L RVGV+LD G+VSF+ G ++ F SS S LRPFF
Sbjct: 401 RPLGRVGVFLDYDNGSVSFFDVSKGSLIYGFPPSSFSSPLRPFF 444
>gi|14719418 tripartite motif protein TRIM5 isoform alpha [Homo
sapiens]
Length = 493
Score = 196 bits (499), Expect = 3e-50
Identities = 149/491 (30%), Positives = 231/491 (47%), Gaps = 53/491 (10%)
Query: 5 DIQEELTCPICLDYFQDPVSIECGHNFCRGCL---HRNWAPGGGPFPCPECRHPSAPAAL 61
+++EE+TCPICL+ P+S++CGH+FC+ CL H+ G CP CR P +
Sbjct: 8 NVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRISYQPENI 67
Query: 62 RPNWALARLTEKTQRRRLGPVPPGL--CGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHA 119
RPN +A L EK + +L P + C RH E L LFC++D + +C +C SQEH+ H
Sbjct: 68 RPNRHVANLVEKLREVKLSPEGQKVDHCARHGEKLLLFCQEDGKVICWLCERSQEHRGHH 127
Query: 120 MAPIDEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRISTEFSK 179
P +E + Y+ KL + L K ++ L+ + WK +I+ + + +F +
Sbjct: 128 TFPTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDKTNVLADFEQ 187
Query: 180 LHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAPTLELL 239
L + L EE LQ L KEEE+ K L + ++ Q SL++LI ++ + Q +ELL
Sbjct: 188 LRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHRLQGSVMELL 247
Query: 240 QNPKEVLTRSEIQDVNYSLEAVKV-----KTVCQIPLMKEMLKRFQVAVNL----AEDTA 290
Q V+ R+E N +L+ + + V + P +K ML+ F+ ++ + T
Sbjct: 248 QGVDGVIKRTE----NVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYWVDVTV 303
Query: 291 HPK----LVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHLPCVLGK 346
P V S++ R V S G R + FV F + +LG
Sbjct: 304 APNNISCAVISEDKRQVS-----------SPKPQIIYGARGTRYQTFV-NFNYCTGILGS 351
Query: 347 NVFTSGKHYWEVESRDSLEVAVGVC---REDVM-GITDRSKMSPDVGIWAI--------- 393
TSGKHYWEV+ +GVC + D M I P G W I
Sbjct: 352 QSITSGKHYWEVDVSKKTAWILGVCAGFQPDAMCNIEKNENYQPKYGYWVIGLEEGVKCS 411
Query: 394 -YWSAAGYWPLIGFPGTPTQQEPALHRVGVYLDRGTGNVSFYSAVD-GVHLHTFSCSSVS 451
+ ++ + P + F P RVGV+LD VSF++ + G ++ FS S S
Sbjct: 412 AFQDSSFHTPSVPFI-VPLSVIICPDRVGVFLDYEACTVSFFNITNHGFLIYKFSHCSFS 470
Query: 452 RLRPFF-WLSP 461
+P F +L+P
Sbjct: 471 --QPVFPYLNP 479
>gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens]
Length = 488
Score = 193 bits (491), Expect = 2e-49
Identities = 154/505 (30%), Positives = 236/505 (46%), Gaps = 66/505 (13%)
Query: 5 DIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPG----GGPFPCPECRHPSAPAA 60
++QEE+TCPICL+ +P+S++CGH+ CR C+ + GG CP C +
Sbjct: 8 NVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSFEH 67
Query: 61 LRPNWALARLTEKTQRRRLGP---VPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQT 117
L+ N LA + E+ + +L P LC H E L LFC++D++ +C +C SQEH+
Sbjct: 68 LQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCERSQEHRG 127
Query: 118 HAMAPIDEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRISTEF 177
H +E F+ +EKL + L + ++ L+ + T WK +++++R RI TEF
Sbjct: 128 HHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQRIQTEF 187
Query: 178 SKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAPTLE 237
+L + L EE LQRL +EE++T K E +L Q +++LI +V +SQ T+E
Sbjct: 188 DQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECRSQWSTME 247
Query: 238 LLQNPKEVLTRSEIQDVNY-SLEAVKVKTVCQIPLMKEMLKRFQ---------VAVNLAE 287
LLQ+ ++ SEI + + + K+KTV P + ML+ F+ V V L
Sbjct: 248 LLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYWVDVTLNS 307
Query: 288 DTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHLPCVLGKN 347
+ LV S++ R V S WP +NY VLG
Sbjct: 308 VNLNLNLVLSEDQRQV---ISVPIWPF--QCYNY--------------------GVLGSQ 342
Query: 348 VFTSGKHYWEVESRDSLEVAVGV-CR--EDVMGITDRSKMSPDVGIWAIYWSAAGYWPL- 403
F+SGKHYWEV+ +GV CR M R + + ++ Y GYW +
Sbjct: 343 YFSSGKHYWEVDVSKKTAWILGVYCRTYSRHMKYVVR-RCANRQNLYTKYRPLFGYWVIG 401
Query: 404 ------IGFPGTPTQQEPAL---------HRVGVYLDRGTGNVSFYSAVD-GVHLHTFS- 446
G +P + RVGV+LD G VSF++ G ++ FS
Sbjct: 402 LQNKCKYGVFEESLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSK 461
Query: 447 CSSVSRLRPFF--WLSPLASLVIPP 469
C + P+F W P + PP
Sbjct: 462 CCFSQPVYPYFNPWNCPAPMTLCPP 486
>gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens]
Length = 488
Score = 193 bits (491), Expect = 2e-49
Identities = 154/505 (30%), Positives = 236/505 (46%), Gaps = 66/505 (13%)
Query: 5 DIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPG----GGPFPCPECRHPSAPAA 60
++QEE+TCPICL+ +P+S++CGH+ CR C+ + GG CP C +
Sbjct: 8 NVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSFEH 67
Query: 61 LRPNWALARLTEKTQRRRLGP---VPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQT 117
L+ N LA + E+ + +L P LC H E L LFC++D++ +C +C SQEH+
Sbjct: 68 LQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCERSQEHRG 127
Query: 118 HAMAPIDEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRISTEF 177
H +E F+ +EKL + L + ++ L+ + T WK +++++R RI TEF
Sbjct: 128 HHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQRIQTEF 187
Query: 178 SKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAPTLE 237
+L + L EE LQRL +EE++T K E +L Q +++LI +V +SQ T+E
Sbjct: 188 DQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECRSQWSTME 247
Query: 238 LLQNPKEVLTRSEIQDVNY-SLEAVKVKTVCQIPLMKEMLKRFQ---------VAVNLAE 287
LLQ+ ++ SEI + + + K+KTV P + ML+ F+ V V L
Sbjct: 248 LLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYWVDVTLNS 307
Query: 288 DTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHLPCVLGKN 347
+ LV S++ R V S WP +NY VLG
Sbjct: 308 VNLNLNLVLSEDQRQV---ISVPIWPF--QCYNY--------------------GVLGSQ 342
Query: 348 VFTSGKHYWEVESRDSLEVAVGV-CR--EDVMGITDRSKMSPDVGIWAIYWSAAGYWPL- 403
F+SGKHYWEV+ +GV CR M R + + ++ Y GYW +
Sbjct: 343 YFSSGKHYWEVDVSKKTAWILGVYCRTYSRHMKYVVR-RCANRQNLYTKYRPLFGYWVIG 401
Query: 404 ------IGFPGTPTQQEPAL---------HRVGVYLDRGTGNVSFYSAVD-GVHLHTFS- 446
G +P + RVGV+LD G VSF++ G ++ FS
Sbjct: 402 LQNKCKYGVFEESLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSK 461
Query: 447 CSSVSRLRPFF--WLSPLASLVIPP 469
C + P+F W P + PP
Sbjct: 462 CCFSQPVYPYFNPWNCPAPMTLCPP 486
>gi|51477690 tripartite motif-containing 6 and tripartite
motif-containing 34 [Homo sapiens]
Length = 842
Score = 193 bits (491), Expect = 2e-49
Identities = 154/505 (30%), Positives = 236/505 (46%), Gaps = 66/505 (13%)
Query: 5 DIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPG----GGPFPCPECRHPSAPAA 60
++QEE+TCPICL+ +P+S++CGH+ CR C+ + GG CP C +
Sbjct: 362 NVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSFEH 421
Query: 61 LRPNWALARLTEKTQRRRLGP---VPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQT 117
L+ N LA + E+ + +L P LC H E L LFC++D++ +C +C SQEH+
Sbjct: 422 LQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCERSQEHRG 481
Query: 118 HAMAPIDEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRISTEF 177
H +E F+ +EKL + L + ++ L+ + T WK +++++R RI TEF
Sbjct: 482 HHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQRIQTEF 541
Query: 178 SKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAPTLE 237
+L + L EE LQRL +EE++T K E +L Q +++LI +V +SQ T+E
Sbjct: 542 DQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECRSQWSTME 601
Query: 238 LLQNPKEVLTRSEIQDVNY-SLEAVKVKTVCQIPLMKEMLKRFQ---------VAVNLAE 287
LLQ+ ++ SEI + + + K+KTV P + ML+ F+ V V L
Sbjct: 602 LLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYWVDVTLNS 661
Query: 288 DTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHLPCVLGKN 347
+ LV S++ R V S WP +NY VLG
Sbjct: 662 VNLNLNLVLSEDQRQV---ISVPIWPF--QCYNY--------------------GVLGSQ 696
Query: 348 VFTSGKHYWEVESRDSLEVAVGV-CR--EDVMGITDRSKMSPDVGIWAIYWSAAGYWPL- 403
F+SGKHYWEV+ +GV CR M R + + ++ Y GYW +
Sbjct: 697 YFSSGKHYWEVDVSKKTAWILGVYCRTYSRHMKYVVR-RCANRQNLYTKYRPLFGYWVIG 755
Query: 404 ------IGFPGTPTQQEPAL---------HRVGVYLDRGTGNVSFYSAVD-GVHLHTFS- 446
G +P + RVGV+LD G VSF++ G ++ FS
Sbjct: 756 LQNKCKYGVFEESLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSK 815
Query: 447 CSSVSRLRPFF--WLSPLASLVIPP 469
C + P+F W P + PP
Sbjct: 816 CCFSQPVYPYFNPWNCPAPMTLCPP 840
Score = 171 bits (432), Expect = 2e-42
Identities = 97/282 (34%), Positives = 159/282 (56%), Gaps = 10/282 (3%)
Query: 5 DIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPG----GGPFPCPECRHPSAPAA 60
DI+EE+TCPICL+ +P+SI+CGH+FC+ C+ N G CP C+ P
Sbjct: 36 DIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQPGN 95
Query: 61 LRPNWALARLTEKTQRRRLGP---VPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQT 117
LRPN LA + + + LGP + LC H E L+LFC++D + +C +C SQEH+
Sbjct: 96 LRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRG 155
Query: 118 HAMAPIDEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRISTEF 177
H ++E + Y+EK +S + L + ++ L + T WK++++ +R RI TEF
Sbjct: 156 HHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEF 215
Query: 178 SKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAPTLE 237
++L N L E L++L +EE++ + + E L SL++LI ++ + Q T+E
Sbjct: 216 NQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQGSTME 275
Query: 238 LLQNPKEVLTRSEIQDVNYSLEAV--KVKTVCQIPLMKEMLK 277
LLQ+ +V RSE + EA+ K++++ + P +K ML+
Sbjct: 276 LLQDVSDVTERSEFWTLR-KPEALPTKLRSMFRAPDLKRMLR 316
>gi|239755488 PREDICTED: similar to ring finger protein 18 isoform 2
[Homo sapiens]
Length = 446
Score = 190 bits (483), Expect = 2e-48
Identities = 131/456 (28%), Positives = 213/456 (46%), Gaps = 27/456 (5%)
Query: 7 QEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAALRPNW- 65
Q EL CPIC++YF DPV+I+CGH+FCR C + NW C EC + L+ N
Sbjct: 10 QRELICPICMNYFIDPVTIDCGHSFCRPCFYLNWKDSPFLVQCSECTKSTGQINLKTNIH 69
Query: 66 --ALARLTEKTQRRRLGPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHAMAPI 123
+A L K +CG H E ++FCE D+ +CL+C SQEH+ H PI
Sbjct: 70 FKKMASLARKVSLWLFLSSEEQMCGTHRETKKMFCEVDRSLLCLLCSSSQEHRDHRHCPI 129
Query: 124 DEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRISTEFSKLHNF 183
+ A E ++EKLL+ ++L K + +VE WKD + + I E+ K+ F
Sbjct: 130 ESAAEEHQEKLLQKMQSLWEKACENHRNLNVETTRTRCWKDYVNLRLEAIRAEYQKMPAF 189
Query: 184 LVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAPTLELLQNPK 243
EEE L+ L K+ ++ +L+ + K+ L+ + E+ E P +ELLQ+
Sbjct: 190 HHEEEKHNLEMLKKKGKDIFHRLHLSKAKMAHRREILRGMYEELNEMCHKPDVELLQDLG 249
Query: 244 EVLTRSEIQDVNYSLEAVKVKTVCQIPLMKEMLKRFQVAVNLAEDTAHPKLVFSQEGRYV 303
+++ RSE ++ T+ I + L F+V + + + + ++ R +
Sbjct: 250 DMVARSESVLLHMPQPVNPELTIGPITGPVDRLNHFRVETSFTWEVTNYNIRLFEDVRSL 309
Query: 304 KNTASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHLPCVLGKNVFTSGKHYWEVESRDS 363
+ + S + FA W G VF+SGKHYWE++ +S
Sbjct: 310 MFRCGSLN----SDRSDNFAAW-------------------GAWVFSSGKHYWELDVDNS 346
Query: 364 LEVAVGVCREDVMGITDRSKMSPDVGIWAIYWSAAGYWPLIGFPGTPTQQEPALHRVGVY 423
+ A+GVC++ + S D+ + + L P P E L RVGV+
Sbjct: 347 WDWALGVCKDSWIRKNSTMVKSKDIFLLLCVKVDNHFSLLTTSPMFPDYVEKPLGRVGVF 406
Query: 424 LDRGTGNVSFYSAVDGVHLHTFSCSSVS-RLRPFFW 458
LD +G+VSF + + ++ S++ +RPFF+
Sbjct: 407 LDFESGSVSFLNVTKSSLIWSYPTGSLNFPVRPFFY 442
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.134 0.423
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,235,381
Number of Sequences: 37866
Number of extensions: 1022922
Number of successful extensions: 5460
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 250
Number of HSP's successfully gapped in prelim test: 299
Number of HSP's that attempted gapping in prelim test: 4436
Number of HSP's gapped (non-prelim): 892
length of query: 474
length of database: 18,247,518
effective HSP length: 106
effective length of query: 368
effective length of database: 14,233,722
effective search space: 5238009696
effective search space used: 5238009696
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.