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Search of human proteins with 149773456
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
(1427 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 2813 0.0
gi|163965366 nascent polypeptide-associated complex alpha subuni... 177 8e-44
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 173 1e-42
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 173 1e-42
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 173 1e-42
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 173 1e-42
gi|160707881 formin 2 [Homo sapiens] 144 6e-34
gi|116284392 mucin 2 precursor [Homo sapiens] 137 1e-31
gi|169205253 PREDICTED: hypothetical protein [Homo sapiens] 136 1e-31
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 132 2e-30
gi|110349719 titin isoform N2-A [Homo sapiens] 127 1e-28
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 122 3e-27
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 120 1e-26
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 115 2e-25
gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens] 113 1e-24
gi|16554449 zonadhesin isoform 3 [Homo sapiens] 112 3e-24
gi|27881494 zonadhesin isoform 6 [Homo sapiens] 112 3e-24
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 110 1e-23
gi|91982772 mucin 17 [Homo sapiens] 110 1e-23
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens] 107 8e-23
gi|238624188 diffuse panbronchiolitis critical region 1 protein ... 105 2e-22
gi|239740773 PREDICTED: similar to diffuse panbronchiolitis crit... 104 5e-22
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 104 5e-22
gi|47132519 Ras association and pleckstrin homology domains 1 is... 104 7e-22
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 104 7e-22
gi|150170670 piccolo isoform 2 [Homo sapiens] 103 2e-21
gi|150378539 piccolo isoform 1 [Homo sapiens] 103 2e-21
gi|110832843 TBP-associated factor 4 [Homo sapiens] 102 3e-21
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 100 1e-20
gi|112421108 capicua homolog [Homo sapiens] 99 2e-20
>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
Length = 1427
Score = 2813 bits (7293), Expect = 0.0
Identities = 1427/1427 (100%), Positives = 1427/1427 (100%)
Query: 1 MGKPLSRPDCLRRNPSCLGKGEEEDGYIEDCYVPQRSIYDTMRINEQIDQGSKLNQTSKS 60
MGKPLSRPDCLRRNPSCLGKGEEEDGYIEDCYVPQRSIYDTMRINEQIDQGSKLNQTSKS
Sbjct: 1 MGKPLSRPDCLRRNPSCLGKGEEEDGYIEDCYVPQRSIYDTMRINEQIDQGSKLNQTSKS 60
Query: 61 TMEKMEGSTISSNGTLGAASNVFESRAPEGKKLDERIIFDALKLSSDVQKSAPVPPRRRP 120
TMEKMEGSTISSNGTLGAASNVFESRAPEGKKLDERIIFDALKLSSDVQKSAPVPPRRRP
Sbjct: 61 TMEKMEGSTISSNGTLGAASNVFESRAPEGKKLDERIIFDALKLSSDVQKSAPVPPRRRP 120
Query: 121 NAERKDNVNRRSWKSFMPPNFPEFAERIEASLSEVSEAGASNPSLQEKKESSSALTESSG 180
NAERKDNVNRRSWKSFMPPNFPEFAERIEASLSEVSEAGASNPSLQEKKESSSALTESSG
Sbjct: 121 NAERKDNVNRRSWKSFMPPNFPEFAERIEASLSEVSEAGASNPSLQEKKESSSALTESSG 180
Query: 181 HLDHREPQSESVTLEHVSKSIGIPEVQDFKNLSGDCQDFRFQQHSANPPHEFQPVESEAV 240
HLDHREPQSESVTLEHVSKSIGIPEVQDFKNLSGDCQDFRFQQHSANPPHEFQPVESEAV
Sbjct: 181 HLDHREPQSESVTLEHVSKSIGIPEVQDFKNLSGDCQDFRFQQHSANPPHEFQPVESEAV 240
Query: 241 ATSGNTDVMQESRFSSATWPRATKSLAKGGFSEKQHPLGDTACTVEMPPLSPCLSEELLD 300
ATSGNTDVMQESRFSSATWPRATKSLAKGGFSEKQHPLGDTACTVEMPPLSPCLSEELLD
Sbjct: 241 ATSGNTDVMQESRFSSATWPRATKSLAKGGFSEKQHPLGDTACTVEMPPLSPCLSEELLD 300
Query: 301 PELHVLITPSLREKTESELKFEEDERWIMMEAEGEWEEEKLSDREKTFLMADEKNSLADI 360
PELHVLITPSLREKTESELKFEEDERWIMMEAEGEWEEEKLSDREKTFLMADEKNSLADI
Sbjct: 301 PELHVLITPSLREKTESELKFEEDERWIMMEAEGEWEEEKLSDREKTFLMADEKNSLADI 360
Query: 361 FEEREQANTAVVEDGSDCLAAVLRTFGHLSLGQICCPDDPQPAKDQLATVPKDIPLDCDC 420
FEEREQANTAVVEDGSDCLAAVLRTFGHLSLGQICCPDDPQPAKDQLATVPKDIPLDCDC
Sbjct: 361 FEEREQANTAVVEDGSDCLAAVLRTFGHLSLGQICCPDDPQPAKDQLATVPKDIPLDCDC 420
Query: 421 VLTGEDILGEVANRTAQGLEGLVSDSACTVGTIDAEQLSDTDSVQMFLELEKECLCEEGV 480
VLTGEDILGEVANRTAQGLEGLVSDSACTVGTIDAEQLSDTDSVQMFLELEKECLCEEGV
Sbjct: 421 VLTGEDILGEVANRTAQGLEGLVSDSACTVGTIDAEQLSDTDSVQMFLELEKECLCEEGV 480
Query: 481 TPLVELQNQISSEGLAASQDAENLLVISHFSGAALEKEQHLGLLHVRAKDYDTRLDCGYF 540
TPLVELQNQISSEGLAASQDAENLLVISHFSGAALEKEQHLGLLHVRAKDYDTRLDCGYF
Sbjct: 481 TPLVELQNQISSEGLAASQDAENLLVISHFSGAALEKEQHLGLLHVRAKDYDTRLDCGYF 540
Query: 541 NTLDSSQVPNAVELIAHVDIMRDTSTVSKEECEKVPFSPRTAEFKSRQPADLDSLEKLDP 600
NTLDSSQVPNAVELIAHVDIMRDTSTVSKEECEKVPFSPRTAEFKSRQPADLDSLEKLDP
Sbjct: 541 NTLDSSQVPNAVELIAHVDIMRDTSTVSKEECEKVPFSPRTAEFKSRQPADLDSLEKLDP 600
Query: 601 GGLLNSDHRVSHEEKLSGFIASELAKDNGSLSQGDCSQTEGNGEECIERVTFSFAFNHEL 660
GGLLNSDHRVSHEEKLSGFIASELAKDNGSLSQGDCSQTEGNGEECIERVTFSFAFNHEL
Sbjct: 601 GGLLNSDHRVSHEEKLSGFIASELAKDNGSLSQGDCSQTEGNGEECIERVTFSFAFNHEL 660
Query: 661 TDVTSGPEVEVLYESNLLTDEIHLESGNVTVNQENNSLTSMGNVVTCELSVEKVCDEDGE 720
TDVTSGPEVEVLYESNLLTDEIHLESGNVTVNQENNSLTSMGNVVTCELSVEKVCDEDGE
Sbjct: 661 TDVTSGPEVEVLYESNLLTDEIHLESGNVTVNQENNSLTSMGNVVTCELSVEKVCDEDGE 720
Query: 721 AKELDYQATLLEDQAPAHFHRNFPEQVFQDLQRKSPESEILSLHLLVEELRLNPDGVETV 780
AKELDYQATLLEDQAPAHFHRNFPEQVFQDLQRKSPESEILSLHLLVEELRLNPDGVETV
Sbjct: 721 AKELDYQATLLEDQAPAHFHRNFPEQVFQDLQRKSPESEILSLHLLVEELRLNPDGVETV 780
Query: 781 NDTKPELNVASSEGGEMERRDSDSFLNIFPEKQVTKAGNTEPVLEEWIPVLQRPSRTAAV 840
NDTKPELNVASSEGGEMERRDSDSFLNIFPEKQVTKAGNTEPVLEEWIPVLQRPSRTAAV
Sbjct: 781 NDTKPELNVASSEGGEMERRDSDSFLNIFPEKQVTKAGNTEPVLEEWIPVLQRPSRTAAV 840
Query: 841 PTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEEEDVTAAA 900
PTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEEEDVTAAA
Sbjct: 841 PTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEEEDVTAAA 900
Query: 901 VSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAI 960
VSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAI
Sbjct: 901 VSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAI 960
Query: 961 TVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAV 1020
TVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAV
Sbjct: 961 TVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAV 1020
Query: 1021 PTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTS 1080
PTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTS
Sbjct: 1021 PTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTS 1080
Query: 1081 PAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTP 1140
PAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTP
Sbjct: 1081 PAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTP 1140
Query: 1141 EEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAA 1200
EEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAA
Sbjct: 1141 EEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAA 1200
Query: 1201 SVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAA 1260
SVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAA
Sbjct: 1201 SVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAA 1260
Query: 1261 VLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPA 1320
VLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPA
Sbjct: 1261 VLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPA 1320
Query: 1321 IPAAAVPPMEEVSPIGVPFLGVSAHTDSVPISEEGTPVLEEASSTGMWIKEDLDSLVFGI 1380
IPAAAVPPMEEVSPIGVPFLGVSAHTDSVPISEEGTPVLEEASSTGMWIKEDLDSLVFGI
Sbjct: 1321 IPAAAVPPMEEVSPIGVPFLGVSAHTDSVPISEEGTPVLEEASSTGMWIKEDLDSLVFGI 1380
Query: 1381 KEVTSTVLHGKVPLAATAGLNSDEVIVHFDSGKGLKSKVRFAGLTWW 1427
KEVTSTVLHGKVPLAATAGLNSDEVIVHFDSGKGLKSKVRFAGLTWW
Sbjct: 1381 KEVTSTVLHGKVPLAATAGLNSDEVIVHFDSGKGLKSKVRFAGLTWW 1427
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 177 bits (448), Expect = 8e-44
Identities = 178/631 (28%), Positives = 247/631 (39%), Gaps = 85/631 (13%)
Query: 790 ASSEGGEMERRDSDSFLNIFPEKQVTK-------AGNTEPVLEEWIPVLQRPSRTAAVPT 842
ASS+G DS S L + Q + AG P+ PV P + +P
Sbjct: 781 ASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPV--SPVEASFLPE 838
Query: 843 VKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPF-------PHEDILVASIVSLEEED 895
+ + SP T P+P+G +A+ P P ++ S+V+L
Sbjct: 839 NSLSFQGSKDSPAT-THSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPK 897
Query: 896 VTAAAVSAPERATVPAVTVSVPEGTAAVAA-----VSSPEETAPAVAAAITQEGMSAVAG 950
A AP++A ++T S P+ A A S + AP AA A
Sbjct: 898 -EGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPAT 956
Query: 951 FSPEWAALAITVPITEEDGTPEGPVTP----ATTVHAPEEPDTAAVRVSTPEEPASPAAA 1006
SP+WA T P GP TP A T A P +TP +P
Sbjct: 957 PSPKWAP---TPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKG-GPATPSPKGAPTPP 1012
Query: 1007 VPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPE-EPTSPAAAVPTPE-- 1063
TP P AA P P+ ++P AA PP P AA P P+ PT+PAA +P+P+
Sbjct: 1013 AVTPPSPKGSPAATPFPKGASTPPAATPP--SPKGSPAATPLPKGAPTTPAATLPSPKGG 1070
Query: 1064 --------EPTSPAAAVPTPE----EPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAV 1111
PT PAA P+P+ P+ A +P P SP + TP +P
Sbjct: 1071 PATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPA 1130
Query: 1112 PTPEEPASPAAAVPTPEEPASPAAAVPTPE----------EPAFPAPAVPTPEESASAAV 1161
TP P A P P +PAA P+P+ P PA P+P+ +
Sbjct: 1131 ATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPK----GGL 1186
Query: 1162 AVPTPEES-ASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAA 1220
A P+P+ + +PAA P+P A + PT+PAA+ P+P +AT +P
Sbjct: 1187 ATPSPKGAPTTPAATPPSPKGGL---ATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTT 1243
Query: 1221 SVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEP 1280
T P A PT PAA P+L+ + TP +P +V TP P
Sbjct: 1244 PAATPPSPKGGPATPPPKGAPTPPAATPPSLK------GGLATPPHKGAPNPAVVTPPSP 1297
Query: 1281 ASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPMEEVSPIGVPFL 1340
A P PAA P+P+ + P P+ P A PP SP G P L
Sbjct: 1298 KGGPATSPPKGAPTPPAATPPSPK----GSPGTPPPKGAPTPPAVTPP----SPKGTPTL 1349
Query: 1341 GVSAHTD----SVPISEEG-TPVLEEASSTG 1366
+ + + P S+EG TP S G
Sbjct: 1350 PATTPSSKGGPTTPSSKEGPTPPAATPSHKG 1380
Score = 164 bits (415), Expect = 6e-40
Identities = 173/598 (28%), Positives = 234/598 (39%), Gaps = 104/598 (17%)
Query: 829 PVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASI 888
PV P PT A S T +A P+P G +V P +
Sbjct: 762 PVASSPKEC---PTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPD 818
Query: 889 VSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAV 948
+ ++ VS E + +P ++S + A SP T P+ A T SAV
Sbjct: 819 TPIGN---LSSPVSPVEASFLPENSLSFQGSKDSPATTHSP--TPPSPKGAPTP---SAV 870
Query: 949 AGFSPEWAALAITVPITEEDGTP---------EGPVTPATTVHAPEEPDTAAVRVSTPEE 999
SP+ +T+P +E TP EGP TPA P++ ++ S+P++
Sbjct: 871 TPLSPK----GVTLP-PKETPTPSVVNLPFPKEGPATPA-----PKQAPALSMTSSSPKK 920
Query: 1000 P-ASPAA----AVPTPE-EPTSPAAAVPTPE----------EPTSPAAAVPPPE------ 1037
A+PA A P+P+ PT PAA P+P+ PT PAA P P+
Sbjct: 921 ARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATP 980
Query: 1038 ----EPTSPAAAVPTPE----------EPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAA 1083
PT PAA P+P+ PT PA TP P AA P P+ ++P A
Sbjct: 981 SPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAV---TPPSPKGSPAATPFPKGASTPPA 1037
Query: 1084 AVPTPEEPTSPAAAVPTPE-EPTSPAAAVPTPEE-PASPA---AAVPTPEEPASPAAAVP 1138
A TP P AA P P+ PT+PAA +P+P+ PA+P+ A P P SP
Sbjct: 1038 A--TPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPA 1095
Query: 1139 TPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSP 1198
TP P P TP S + TP +P TP A PT+P
Sbjct: 1096 TPSPKGAPMPPAATPP---SPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTP 1152
Query: 1199 AASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSA 1258
AA+ P+P +AT +P T P A S PT+PAA P S
Sbjct: 1153 AATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT------PPSPK 1206
Query: 1259 AAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPE--VAAIPAASVPTP 1316
+ TP +P TP P A S P +PAA P+P+ A P PTP
Sbjct: 1207 GGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTP 1266
Query: 1317 EV---PAI--------------PAAAVPPMEEVSPIGVPFLGVSAHTDSVPISEEGTP 1357
P++ PA PP + P P G + P S +G+P
Sbjct: 1267 PAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSP 1324
Score = 135 bits (340), Expect = 3e-31
Identities = 162/599 (27%), Positives = 236/599 (39%), Gaps = 95/599 (15%)
Query: 815 TKAGNTEPVLEEWIPVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAA 874
+K G T P +E P+ AA P+ K PSP+ G A+P+P+G A
Sbjct: 1356 SKGGPTTPSSKEG------PTPPAATPSHKGGPAMTPPSPKRGP---AIPSPKGDPTSPA 1406
Query: 875 LVPF-----PHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSP 929
++P P + + + D+T AV+ PA S P+G A + S
Sbjct: 1407 VIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPAT--SAPKGGPATPS-SKG 1463
Query: 930 EETAPAVAAAITQEGMS---AVAGFSPEWAAL------AITVPITEEDGTPEGPVTPATT 980
+ T PAV +E + SP+ A A T+P E P TP++
Sbjct: 1464 DPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSR 1523
Query: 981 VHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPT 1040
P P + TP A A +P PA VP+P++ A+P P+E
Sbjct: 1524 -RDPIAPTATLLSKKTPATLAPKEALIP-------PAMTVPSPKK----TPAIPTPKE-- 1569
Query: 1041 SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE-PTSPAAAVPTPEE-PTSPAAAV 1098
A A P+ +E +SP A P S P+P+E PA P+P+E PT PA
Sbjct: 1570 --APATPSSKEASSPPAVTP------STYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTP 1621
Query: 1099 PTPEE-PTSPAAAVPTPEEPASPAAAVPTPEEPAS----PAAAVPTPEEPAFPAPAVPTP 1153
P+PE+ P +PA P +P++ +P PAS A VP + PA PT
Sbjct: 1622 PSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASK-GLPAKKGPT- 1679
Query: 1154 EESASAAVAVPTPEESASPAAAVPT---PAESASFAAVVATLEEPTSP-----AASVPTP 1205
+ + P PE ++P PT P S A +P++ S P
Sbjct: 1680 --ALKEVLVAPAPE--STPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAP 1735
Query: 1206 AAMVATLEEFTSPAASVPTSEEP-ASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTP 1264
A ++ ++ + A S P LA S P + AA L +P S++ +
Sbjct: 1736 APLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPS 1795
Query: 1265 EELSSPAASVPTPE-------EPASPAAAVSNLEEPASPA-------AAVPTPEVAAIPA 1310
+S P A P P P+SP + + +P +PA P P +P
Sbjct: 1796 PPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPF 1855
Query: 1311 ASV----PTPEVPAIPAAAVPPMEEVSPIGVPFLGVSAHTDSVPISEEGTPVLEEASST 1365
SV PTP+ IP VP P+ G +D S+E P LEE ST
Sbjct: 1856 QSVLVNMPTPKSAGIP---VPTPSAKQPVTKNNKGSGTESD----SDESVPELEEQDST 1907
Score = 129 bits (325), Expect = 2e-29
Identities = 173/649 (26%), Positives = 240/649 (36%), Gaps = 161/649 (24%)
Query: 831 LQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPF---------PHE 881
L P A P++K A +P A P+P+G + A P PH+
Sbjct: 1064 LPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHK 1123
Query: 882 DILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAIT 941
+ A T PA T P+G A + P + AP AA
Sbjct: 1124 GAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLA----TPPPKGAPTTPAATP 1179
Query: 942 QEGMSAVAGFSPEWAALA-ITVPITEEDG----TPEG-PVTPATTVHAPE---------- 985
+A SP+ A P + + G +P+G P TPA T +P+
Sbjct: 1180 PSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKG 1239
Query: 986 EPDTAAVRVSTPE----------EPASPAAAVP-------TPEEPTSPAAAVPTPEEPTS 1028
P T A +P+ P PAA P TP +P AV TP P
Sbjct: 1240 APTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKG 1299
Query: 1029 PAAAVPPPEEPTSPAAAVPTPE----------EPTSPAAAVPTPE-EPTSPAAA------ 1071
A PP PT PAA P+P+ PT PA P+P+ PT PA
Sbjct: 1300 GPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGG 1359
Query: 1072 --VPTPEEPTSPAAAVPTPE-----EPTSP--AAAVPTPE-EPTSPAAAVPTPEE-PASP 1120
P+ +E +P AA P+ + P SP A+P+P+ +PTSPA +P++ PA+P
Sbjct: 1360 PTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATP 1419
Query: 1121 A----AAVP-----------------------------TPE---EPASPAAAVPTPEEPA 1144
AA P TP +P PA P+P+EP
Sbjct: 1420 VTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPP 1479
Query: 1145 FP-----------APAVPTPEESASAAVAVP--------TPEESASPAAAVPT------P 1179
P APA P P + + +P TP P A T P
Sbjct: 1480 APKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTP 1539
Query: 1180 AESASFAAVVATLEEPTSP--AASVPTPAAMVAT--LEEFTSPAASVPTSEEPAS----- 1230
A A A++ SP ++PTP AT +E +SP A P++ + A
Sbjct: 1540 ATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKEL 1599
Query: 1231 -LAAAVSNP---EEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAA 1286
+ AV++P E PT PA P+ E+ ++ A TP S P + P SPA+
Sbjct: 1600 LIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTP--TSPPVTPSSLKDSPTSPASV 1657
Query: 1287 VSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPMEEVSPI 1335
+ A VP +PA PT A+ V P E +PI
Sbjct: 1658 TCKM------GATVPQAS-KGLPAKKGPT----ALKEVLVAPAPESTPI 1695
Score = 105 bits (261), Expect = 4e-22
Identities = 146/551 (26%), Positives = 208/551 (37%), Gaps = 99/551 (17%)
Query: 907 ATVPAVTVSVPEGTAAVAAVS-SPEETAPAVAAAITQEGMSAVAGFSPEWA---ALAITV 962
A P V SV +G + +++++ SP + + S + SP L +
Sbjct: 372 AAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQM 431
Query: 963 PITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPE--------EPASPAAAVPTPEEPT 1014
P++ TP P T AP A VS P EP SPAA V P P
Sbjct: 432 PVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPK 491
Query: 1015 SPAAAVPTPEE-PTSPAAAVPPPEE----PTSPAAAVPTPEE-PTSPAAAVPTPEEPTSP 1068
P+ V T P SP +P PE+ P+S PT ++ T PA+ P P
Sbjct: 492 EPSTQVATTLRIPVSPP--LPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQ- 548
Query: 1069 AAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPE--EP---ASPAAA 1123
A + T ++PT P+ S + +PE P SP A + EP PA++
Sbjct: 549 -AGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASS 607
Query: 1124 VPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESA 1183
+ +P S A+ + T + A P A P + S P ESA PA PT A+
Sbjct: 608 MTSPLGVNSSASVIKT-DSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGT 666
Query: 1184 SFAAVVAT--LEEPTSPA-ASVPTPAAMVATLEEFTSPAASVPTSEEP----ASLAAAVS 1236
S A+ LE S A + P + TL + + + P + P A LA V
Sbjct: 667 STYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVL 726
Query: 1237 NPEEPTS-PAAAVPTLEEP-----------TSSAAAVLT-----PEELSSPAASV----- 1274
PE P S P+ ++P P TS+ A V + P E S +A+
Sbjct: 727 APEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGT 786
Query: 1275 ----------------------PTPEEPASPAAAVSNLEEPASPAAAVPTPE-------- 1304
PT + A P + NL P SP A PE
Sbjct: 787 LTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGS 846
Query: 1305 ---VAAIPAASVPTPEVPAIPAAAVPPMEEVSPIGVPFLGVSAHTDSV---PISEEG--T 1356
A + + P+P+ P+A P +SP GV T SV P +EG T
Sbjct: 847 KDSPATTHSPTPPSPKGAPTPSAVTP----LSPKGVTLPPKETPTPSVVNLPFPKEGPAT 902
Query: 1357 PVLEEASSTGM 1367
P ++A + M
Sbjct: 903 PAPKQAPALSM 913
Score = 99.0 bits (245), Expect = 3e-20
Identities = 125/499 (25%), Positives = 190/499 (38%), Gaps = 83/499 (16%)
Query: 822 PVLEEWIPVLQRPSRTAAVPTVKD--ALDAALP-SPEE-------GTSIA-----AVPAP 866
PV + P P A P+ K L A P SP+E TS + A PAP
Sbjct: 1440 PVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAP 1499
Query: 867 EGTAVVAALVPFPHEDILVASIVSLEEEDVTAAAVS-------APERATVP-AVTVSVPE 918
G + A++P +++ + TA +S AP+ A +P A+TV P+
Sbjct: 1500 MGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPK 1559
Query: 919 GTAAV-------AAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTP 971
T A+ A SS E ++P T +G +P L I +T
Sbjct: 1560 KTPAIPTPKEAPATPSSKEASSPPAVTPSTYKG-------APSPKELLIPPAVTSPS-PK 1611
Query: 972 EGPVTPATTVHAPEE-PDTAAVRVSTPEEPASPAAAVPTPEEPTS---------PAAA-- 1019
E P PA T +PE+ P T A + + P +P++ +P P S P A+
Sbjct: 1612 EAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKG 1671
Query: 1020 VPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPT--PEE 1077
+P + PT+ + P ++P PT + P + ++ +P P+A + P
Sbjct: 1672 LPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLS 1731
Query: 1078 PTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAA----VPTPEEPASPAAAVPTPEEPASP 1133
+PA +P ++ + A P P A TP A+ +P PE +
Sbjct: 1732 TVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVS 1791
Query: 1134 AAAVPTPEEPAFPAPAVPTPEES----ASAAVAVPTPEESASPA-------AAVPTPAES 1182
AA P P P+P P + +S + + +P + +PA P P
Sbjct: 1792 AAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISG 1851
Query: 1183 A-SFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAA------SVPTSEEP------- 1228
F +V+ + P S VPTP+A + SVP EE
Sbjct: 1852 GVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATT 1911
Query: 1229 --ASLAAAVSNPEEPTSPA 1245
A LAAA EEP S A
Sbjct: 1912 QQAQLAAAAEIDEEPVSKA 1930
Score = 88.2 bits (217), Expect = 5e-17
Identities = 140/585 (23%), Positives = 213/585 (36%), Gaps = 60/585 (10%)
Query: 816 KAGNTEPVLEEWIPVLQRPSRTAAVPTVKDALD--AALPSPEEGTSIAAVPAPEGTAVVA 873
+A T P E+ +P +P AV + AL AAL P PAP+ + A
Sbjct: 4 EATETVPATEQELP---QPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSA 60
Query: 874 A--LVPFPHEDILVASIVSL---EEEDVTAAAV-SAPERATVPAVTVSVPEGTAAVAAVS 927
A PFP + ++ + + + TA + +APE T + P AA+A S
Sbjct: 61 ANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALAS 120
Query: 928 ---------SPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTPA 978
+P +AP A+ + + F P +V + E G V
Sbjct: 121 PMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAES-----GSVITL 175
Query: 979 TTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEE 1038
+ AP EP T +V P+ VP P+ SP V T P V P
Sbjct: 176 SAPIAPSEPKTNLNKV--------PSEVVPNPKGTPSPPCIV-----STVPYHCVTPMAS 222
Query: 1039 PTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAV 1098
S A++P T+ A A P ++ T + + +P+ P S + P +
Sbjct: 223 IQSGVASLPQTTPTTTLAIASPQVKDTTISSVLI-SPQNPGSLSLKGPVSPPAALSLSTQ 281
Query: 1099 PTPEEPTSPAAAVPT--PEEPASPAA-AVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEE 1155
P +S A P P+ P S + P + + A P V T
Sbjct: 282 SLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISV 341
Query: 1156 SASAAVAVPTPEESA---SPAAAVPTPAESASFAAVVATLEEPTSPAASVP-TPAAMVAT 1211
S+ A + S P+ PA A+F V ++++ S +S+ +P+ +
Sbjct: 342 DHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNV 401
Query: 1212 LEEFT-SPAASVPTSEEPASLAAAVSNPEEPTSPAAAVP-TLEEPTSSAAAVLTPEELSS 1269
F+ SP S+ P + + P S P + P + AAA T E
Sbjct: 402 ATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFE--- 458
Query: 1270 PAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTP-EVPAIPAAAVPP 1328
V T P + +SN+ EP SPAA V P P+ V T +P P P
Sbjct: 459 ----VATCVSPPMSSGPISNI-EPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPE 513
Query: 1329 MEEVSPIGVPF-LGVSAHTDSVPISEEGTPVLEEASSTGMWIKED 1372
+ P V +VP S EG P + G+ K+D
Sbjct: 514 DLKNLPSSVLVKFPTQKDLQTVPASLEGAPF--SPAQAGLTTKKD 556
Score = 63.9 bits (154), Expect = 1e-09
Identities = 90/400 (22%), Positives = 149/400 (37%), Gaps = 46/400 (11%)
Query: 1000 PASPAAAVPTPEE----PTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSP 1055
P VP E+ P + A +P + AA P PT P P P++
Sbjct: 2 PGEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPG--PTLPPPCSPAPQQCPLS 59
Query: 1056 AA--AVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPT 1113
AA A P P T + + P +S A+P P +P P SPAA
Sbjct: 60 AANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALA 119
Query: 1114 PEEPASPAAAVPTPEEPASPAAAVP--TPEEPAFPAPAVPTPEESA----------SAAV 1161
A P+ P + A P + AFP + +P A SA +
Sbjct: 120 SPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPI 179
Query: 1162 AVPTPEESAS--PAAAVPTPAESASFAAVVATLE-EPTSPAASVPTPAAMVATLEEFTSP 1218
A P+ + + P+ VP P + S +V+T+ +P AS+ + A + T+
Sbjct: 180 APSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTL 239
Query: 1219 AASVPTSEEPASLAAAVSNPEEPTS-----PAAAVPTLEEPTSSAAAVLTPEELSSPAAS 1273
A + P ++ ++++ + +P+ P S P + L T S V + ++ + P
Sbjct: 240 AIASPQVKD-TTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTP 298
Query: 1274 VPTPEEPASPAA--------AVSNLEEPASPAAAVPTPEVAAI----PAASVPTPE--VP 1319
P S A +V L + A + PT + ++ AS P+ +P
Sbjct: 299 PDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIP 358
Query: 1320 AIPA--AAVPPMEEVSPIGVPFLGVSAHT-DSVPISEEGT 1356
+P+ VP P+ P + T S+ S G+
Sbjct: 359 PLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGS 398
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 173 bits (438), Expect = 1e-42
Identities = 167/627 (26%), Positives = 222/627 (35%), Gaps = 66/627 (10%)
Query: 810 PEKQVTKAGNTEPVLEEWIPVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGT 869
P TK+ T P +E P ++ A T K+ P T+ +A P+
Sbjct: 247 PAPTTTKSAPTTP--KEPAPTT---TKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP 301
Query: 870 AVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSP 929
A P P + +E T P PA T P T P
Sbjct: 302 APTTPKKPAP---------TTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP----KEP 348
Query: 930 EETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTP----EGPVT-----PATT 980
TAP A T + + P P T ++ P P T P TT
Sbjct: 349 APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 408
Query: 981 VHAP---EEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPT-PEEPTSPAAAVPPP 1036
AP +EP + P P PA P PT+P PT P+EP P P
Sbjct: 409 KSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAP 468
Query: 1037 EEPTSPAAAVPTPEEPTSPAAAVPTPEE---PTSPAAAVPT-PEE--PTSPAAAVPT-PE 1089
P PA P PT+P PT E PT+P PT PEE PT+P PT PE
Sbjct: 469 TTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPE 528
Query: 1090 EP--TSPAAAVP-TPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTP-EEPAF 1145
EP T+P AA P TP+EP P P P PA P P +P PT +EPA
Sbjct: 529 EPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAP 588
Query: 1146 PAPAVPTPEESASAAVAVPTPEESASPAAAVPT-----------------PAESASFAAV 1188
P P P+E A PT PA P PA +
Sbjct: 589 TTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTA 648
Query: 1189 VATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAV 1248
TL+EP P P + T T+ + TS++PA + P P PA
Sbjct: 649 PTTLKEPAPTTPKKPAPKELAPT----TTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTT 704
Query: 1249 PTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAI 1308
P PT+ T E+S+P + SP + L +P A +P+ +
Sbjct: 705 PKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGV 764
Query: 1309 PAASVPTPEVPAIPAAAVPPMEEVSPIGVPFLGVSA---HTDSVPISEEGTPVLEEASST 1365
P P P + A E P +A ++ +E+ T A++T
Sbjct: 765 PTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTT 824
Query: 1366 GMWIKEDLDSLVFGIKEVTSTVLHGKV 1392
+ D+ F I + +T L KV
Sbjct: 825 QVTSTTTQDTTPFKITTLKTTTLAPKV 851
Score = 168 bits (425), Expect = 4e-41
Identities = 164/601 (27%), Positives = 220/601 (36%), Gaps = 76/601 (12%)
Query: 811 EKQVTKAGNTEPVLEEWIPVLQRPSRTAAVPTVKDALDA---ALPSPEEGTSIAAVPAPE 867
+++ T A T+ + + L S+ A PT K AL +P+E P P
Sbjct: 167 KEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKE-------PTPT 219
Query: 868 GTAVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVS 927
A+ P + S + +E SAP PA T T A +
Sbjct: 220 TPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPT------TTKEPAPT 273
Query: 928 SPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEP 987
+P+E AP T+E + P T ++ P P PA T P+EP
Sbjct: 274 TPKEPAPTT----TKEPAPTTTK----------SAPTTPKEPAPTTPKKPAPTT--PKEP 317
Query: 988 DTAAVRVSTPEEP--ASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAA 1045
+TP+EP +P PT +EP P P P PA P PT+P
Sbjct: 318 AP-----TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEP 372
Query: 1046 VPTPEE---PTSPAAAVPTPEE----------PTSPAAAVPTPEEPTSPAAAVPTPEEPT 1092
PT + PT+P PT + PT+ +A TP+EP+ P P P
Sbjct: 373 APTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK 432
Query: 1093 SPAAAVPTPEEPTSPAAAVP-TPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVP 1151
PA P PT+P P TP+EPA P P P PA P P P P
Sbjct: 433 EPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTP 492
Query: 1152 -TPEESASAAVAVP---TPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPT--- 1204
TPE+ A P TPEE A PTP A P +P PT
Sbjct: 493 TTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPK 552
Query: 1205 -PAAMVATLEEFTSPAASVPTSEE---PASL-AAAVSNPEEPTSPAAAVPTLEEPTSSAA 1259
PA T+P + PT+ + P +L A + P++P A T +EPTS+
Sbjct: 553 EPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTC 612
Query: 1260 ---AVLTPEELSSPAASVPTPEEPASPA------AAVSNLEEPASPAAAVPTPEVAAIPA 1310
A TP+ + P P P PA A + L+EPA P P+ A
Sbjct: 613 DKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 672
Query: 1311 ASVPTPEVPAIPAAAVPPMEEVSPIGVPFLGVSAHTDSVPISEEGTPVLEEASSTGMWIK 1370
PT PA P +E +P + P + E P ST K
Sbjct: 673 TKGPTSTTSDKPAPTTP--KETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTK 730
Query: 1371 E 1371
E
Sbjct: 731 E 731
Score = 119 bits (298), Expect = 2e-26
Identities = 117/418 (27%), Positives = 165/418 (39%), Gaps = 55/418 (13%)
Query: 965 TEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEE-----PTSPAAA 1019
T++ TP+ PV A D +V+TP+ + V T + P +P +
Sbjct: 74 TKKKPTPKPPVVD----EAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPS 129
Query: 1020 VPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE-- 1077
+P P TS ++ +E T T + TS T + + + ++
Sbjct: 130 LP-PNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLA 188
Query: 1078 PTSPAAAVPTPE-EPTSPAAAVPTPEEPT-----SPAAAVPTPEEPASPAAAVPTPEEPA 1131
PTS A PTP+ E T+ A+ TP+EPT PA+ P P + +A TP+EPA
Sbjct: 189 PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA 248
Query: 1132 --SPAAAVPTPEEPA---FPAPAVPTPEESASAAVAVPTPEESAS-------PAAAVP-- 1177
+ +A TP+EPA PA TP+E A P P + S PA P
Sbjct: 249 PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 308
Query: 1178 ----TPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTS-------- 1225
TP E A T P PA + PA T+P PT+
Sbjct: 309 PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT 368
Query: 1226 -EEPASLAAAVSNPEEPTSPA-----AAVPTLEE--PTSSAAAVLTPEELSSPAASVPTP 1277
+EPA +P P PA +A T +E PT++ +A TP+E S P P
Sbjct: 369 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 428
Query: 1278 EEPASPAAAVSNLEEPASPAAAVP-TPEVAAIPAASVPTPEVPAIPAAAVPPMEEVSP 1334
P PA P +P P TP+ A P P P PA P +E +P
Sbjct: 429 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP--KETAP 484
Score = 104 bits (259), Expect = 7e-22
Identities = 119/473 (25%), Positives = 171/473 (36%), Gaps = 52/473 (10%)
Query: 841 PTVKDALDAALPSPEEGT-SIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEEEDVTAA 899
PT + L A +PEE T + PAP A P +E T
Sbjct: 508 PTTPEEL--APTTPEEPTPTTPEEPAPTTPKAAAPNTP--------------KEPAPTTP 551
Query: 900 AVSAPERATVPAVTV------SVPEGTAAVA----AVSSPEETAPAVAAAITQEGMSAVA 949
AP PA T + P+GTA A ++P++ AP A T + ++
Sbjct: 552 KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 611
Query: 950 GFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRV-STPEEPASPAAAVP 1008
P T P T ++ P P PA T P T +TP++PA A
Sbjct: 612 CDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 671
Query: 1009 TPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSP 1068
T + PTS + P P P A P P PA P PT+P PT E ++P
Sbjct: 672 TTKGPTSTTSDKPAPTTPKETA-----PTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTP 726
Query: 1069 AAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPE 1128
T +EPT+ +P+E T +A PTP+ A +P+EP P P
Sbjct: 727 T----TTKEPTT---IHKSPDESTPELSAEPTPK------ALENSPKEPGVPTTKTPAAT 773
Query: 1129 EP-ASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAA 1187
+P + A T E P T + A T + + S A T S +
Sbjct: 774 KPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQD 833
Query: 1188 VV---ATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSP 1244
T + T+ A V T + T E P + + + A P++PT
Sbjct: 834 TTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTK- 892
Query: 1245 AAAVPTLEEPTSSAAAVLTPEELSSPAASVPT-PEEPASPAAAVSNLEEPASP 1296
A PT + + V P+ +P T PE + A + L+ P
Sbjct: 893 APKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRP 945
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 173 bits (438), Expect = 1e-42
Identities = 167/627 (26%), Positives = 222/627 (35%), Gaps = 66/627 (10%)
Query: 810 PEKQVTKAGNTEPVLEEWIPVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGT 869
P TK+ T P +E P ++ A T K+ P T+ +A P+
Sbjct: 288 PAPTTTKSAPTTP--KEPAPTT---TKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP 342
Query: 870 AVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSP 929
A P P + +E T P PA T P T P
Sbjct: 343 APTTPKKPAP---------TTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP----KEP 389
Query: 930 EETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTP----EGPVT-----PATT 980
TAP A T + + P P T ++ P P T P TT
Sbjct: 390 APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 449
Query: 981 VHAP---EEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPT-PEEPTSPAAAVPPP 1036
AP +EP + P P PA P PT+P PT P+EP P P
Sbjct: 450 KSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAP 509
Query: 1037 EEPTSPAAAVPTPEEPTSPAAAVPTPEE---PTSPAAAVPT-PEE--PTSPAAAVPT-PE 1089
P PA P PT+P PT E PT+P PT PEE PT+P PT PE
Sbjct: 510 TTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPE 569
Query: 1090 EP--TSPAAAVP-TPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTP-EEPAF 1145
EP T+P AA P TP+EP P P P PA P P +P PT +EPA
Sbjct: 570 EPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAP 629
Query: 1146 PAPAVPTPEESASAAVAVPTPEESASPAAAVPT-----------------PAESASFAAV 1188
P P P+E A PT PA P PA +
Sbjct: 630 TTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTA 689
Query: 1189 VATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAV 1248
TL+EP P P + T T+ + TS++PA + P P PA
Sbjct: 690 PTTLKEPAPTTPKKPAPKELAPT----TTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTT 745
Query: 1249 PTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAI 1308
P PT+ T E+S+P + SP + L +P A +P+ +
Sbjct: 746 PKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGV 805
Query: 1309 PAASVPTPEVPAIPAAAVPPMEEVSPIGVPFLGVSA---HTDSVPISEEGTPVLEEASST 1365
P P P + A E P +A ++ +E+ T A++T
Sbjct: 806 PTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTT 865
Query: 1366 GMWIKEDLDSLVFGIKEVTSTVLHGKV 1392
+ D+ F I + +T L KV
Sbjct: 866 QVTSTTTQDTTPFKITTLKTTTLAPKV 892
Score = 168 bits (425), Expect = 4e-41
Identities = 164/601 (27%), Positives = 220/601 (36%), Gaps = 76/601 (12%)
Query: 811 EKQVTKAGNTEPVLEEWIPVLQRPSRTAAVPTVKDALDA---ALPSPEEGTSIAAVPAPE 867
+++ T A T+ + + L S+ A PT K AL +P+E P P
Sbjct: 208 KEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKE-------PTPT 260
Query: 868 GTAVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVS 927
A+ P + S + +E SAP PA T T A +
Sbjct: 261 TPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPT------TTKEPAPT 314
Query: 928 SPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEP 987
+P+E AP T+E + P T ++ P P PA T P+EP
Sbjct: 315 TPKEPAPTT----TKEPAPTTTK----------SAPTTPKEPAPTTPKKPAPTT--PKEP 358
Query: 988 DTAAVRVSTPEEP--ASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAA 1045
+TP+EP +P PT +EP P P P PA P PT+P
Sbjct: 359 AP-----TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEP 413
Query: 1046 VPTPEE---PTSPAAAVPTPEE----------PTSPAAAVPTPEEPTSPAAAVPTPEEPT 1092
PT + PT+P PT + PT+ +A TP+EP+ P P P
Sbjct: 414 APTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK 473
Query: 1093 SPAAAVPTPEEPTSPAAAVP-TPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVP 1151
PA P PT+P P TP+EPA P P P PA P P P P
Sbjct: 474 EPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTP 533
Query: 1152 -TPEESASAAVAVP---TPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPT--- 1204
TPE+ A P TPEE A PTP A P +P PT
Sbjct: 534 TTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPK 593
Query: 1205 -PAAMVATLEEFTSPAASVPTSEE---PASL-AAAVSNPEEPTSPAAAVPTLEEPTSSAA 1259
PA T+P + PT+ + P +L A + P++P A T +EPTS+
Sbjct: 594 EPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTC 653
Query: 1260 ---AVLTPEELSSPAASVPTPEEPASPA------AAVSNLEEPASPAAAVPTPEVAAIPA 1310
A TP+ + P P P PA A + L+EPA P P+ A
Sbjct: 654 DKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 713
Query: 1311 ASVPTPEVPAIPAAAVPPMEEVSPIGVPFLGVSAHTDSVPISEEGTPVLEEASSTGMWIK 1370
PT PA P +E +P + P + E P ST K
Sbjct: 714 TKGPTSTTSDKPAPTTP--KETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTK 771
Query: 1371 E 1371
E
Sbjct: 772 E 772
Score = 119 bits (298), Expect = 2e-26
Identities = 117/418 (27%), Positives = 165/418 (39%), Gaps = 55/418 (13%)
Query: 965 TEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEE-----PTSPAAA 1019
T++ TP+ PV A D +V+TP+ + V T + P +P +
Sbjct: 115 TKKKPTPKPPVVD----EAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPS 170
Query: 1020 VPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE-- 1077
+P P TS ++ +E T T + TS T + + + ++
Sbjct: 171 LP-PNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLA 229
Query: 1078 PTSPAAAVPTPE-EPTSPAAAVPTPEEPT-----SPAAAVPTPEEPASPAAAVPTPEEPA 1131
PTS A PTP+ E T+ A+ TP+EPT PA+ P P + +A TP+EPA
Sbjct: 230 PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA 289
Query: 1132 --SPAAAVPTPEEPA---FPAPAVPTPEESASAAVAVPTPEESAS-------PAAAVP-- 1177
+ +A TP+EPA PA TP+E A P P + S PA P
Sbjct: 290 PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 349
Query: 1178 ----TPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTS-------- 1225
TP E A T P PA + PA T+P PT+
Sbjct: 350 PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT 409
Query: 1226 -EEPASLAAAVSNPEEPTSPA-----AAVPTLEE--PTSSAAAVLTPEELSSPAASVPTP 1277
+EPA +P P PA +A T +E PT++ +A TP+E S P P
Sbjct: 410 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 469
Query: 1278 EEPASPAAAVSNLEEPASPAAAVP-TPEVAAIPAASVPTPEVPAIPAAAVPPMEEVSP 1334
P PA P +P P TP+ A P P P PA P +E +P
Sbjct: 470 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP--KETAP 525
Score = 104 bits (259), Expect = 7e-22
Identities = 119/473 (25%), Positives = 171/473 (36%), Gaps = 52/473 (10%)
Query: 841 PTVKDALDAALPSPEEGT-SIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEEEDVTAA 899
PT + L A +PEE T + PAP A P +E T
Sbjct: 549 PTTPEEL--APTTPEEPTPTTPEEPAPTTPKAAAPNTP--------------KEPAPTTP 592
Query: 900 AVSAPERATVPAVTV------SVPEGTAAVA----AVSSPEETAPAVAAAITQEGMSAVA 949
AP PA T + P+GTA A ++P++ AP A T + ++
Sbjct: 593 KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 652
Query: 950 GFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRV-STPEEPASPAAAVP 1008
P T P T ++ P P PA T P T +TP++PA A
Sbjct: 653 CDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 712
Query: 1009 TPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSP 1068
T + PTS + P P P A P P PA P PT+P PT E ++P
Sbjct: 713 TTKGPTSTTSDKPAPTTPKETA-----PTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTP 767
Query: 1069 AAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPE 1128
T +EPT+ +P+E T +A PTP+ A +P+EP P P
Sbjct: 768 T----TTKEPTT---IHKSPDESTPELSAEPTPK------ALENSPKEPGVPTTKTPAAT 814
Query: 1129 EP-ASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAA 1187
+P + A T E P T + A T + + S A T S +
Sbjct: 815 KPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQD 874
Query: 1188 VV---ATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSP 1244
T + T+ A V T + T E P + + + A P++PT
Sbjct: 875 TTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTK- 933
Query: 1245 AAAVPTLEEPTSSAAAVLTPEELSSPAASVPT-PEEPASPAAAVSNLEEPASP 1296
A PT + + V P+ +P T PE + A + L+ P
Sbjct: 934 APKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRP 986
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 173 bits (438), Expect = 1e-42
Identities = 167/627 (26%), Positives = 222/627 (35%), Gaps = 66/627 (10%)
Query: 810 PEKQVTKAGNTEPVLEEWIPVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGT 869
P TK+ T P +E P ++ A T K+ P T+ +A P+
Sbjct: 340 PAPTTTKSAPTTP--KEPAPTT---TKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP 394
Query: 870 AVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSP 929
A P P + +E T P PA T P T P
Sbjct: 395 APTTPKKPAP---------TTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP----KEP 441
Query: 930 EETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTP----EGPVT-----PATT 980
TAP A T + + P P T ++ P P T P TT
Sbjct: 442 APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 501
Query: 981 VHAP---EEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPT-PEEPTSPAAAVPPP 1036
AP +EP + P P PA P PT+P PT P+EP P P
Sbjct: 502 KSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAP 561
Query: 1037 EEPTSPAAAVPTPEEPTSPAAAVPTPEE---PTSPAAAVPT-PEE--PTSPAAAVPT-PE 1089
P PA P PT+P PT E PT+P PT PEE PT+P PT PE
Sbjct: 562 TTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPE 621
Query: 1090 EP--TSPAAAVP-TPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTP-EEPAF 1145
EP T+P AA P TP+EP P P P PA P P +P PT +EPA
Sbjct: 622 EPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAP 681
Query: 1146 PAPAVPTPEESASAAVAVPTPEESASPAAAVPT-----------------PAESASFAAV 1188
P P P+E A PT PA P PA +
Sbjct: 682 TTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTA 741
Query: 1189 VATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAV 1248
TL+EP P P + T T+ + TS++PA + P P PA
Sbjct: 742 PTTLKEPAPTTPKKPAPKELAPT----TTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTT 797
Query: 1249 PTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAI 1308
P PT+ T E+S+P + SP + L +P A +P+ +
Sbjct: 798 PKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGV 857
Query: 1309 PAASVPTPEVPAIPAAAVPPMEEVSPIGVPFLGVSA---HTDSVPISEEGTPVLEEASST 1365
P P P + A E P +A ++ +E+ T A++T
Sbjct: 858 PTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTT 917
Query: 1366 GMWIKEDLDSLVFGIKEVTSTVLHGKV 1392
+ D+ F I + +T L KV
Sbjct: 918 QVTSTTTQDTTPFKITTLKTTTLAPKV 944
Score = 168 bits (425), Expect = 4e-41
Identities = 164/601 (27%), Positives = 220/601 (36%), Gaps = 76/601 (12%)
Query: 811 EKQVTKAGNTEPVLEEWIPVLQRPSRTAAVPTVKDALDA---ALPSPEEGTSIAAVPAPE 867
+++ T A T+ + + L S+ A PT K AL +P+E P P
Sbjct: 260 KEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKE-------PTPT 312
Query: 868 GTAVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVS 927
A+ P + S + +E SAP PA T T A +
Sbjct: 313 TPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPT------TTKEPAPT 366
Query: 928 SPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEP 987
+P+E AP T+E + P T ++ P P PA T P+EP
Sbjct: 367 TPKEPAPTT----TKEPAPTTTK----------SAPTTPKEPAPTTPKKPAPTT--PKEP 410
Query: 988 DTAAVRVSTPEEP--ASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAA 1045
+TP+EP +P PT +EP P P P PA P PT+P
Sbjct: 411 AP-----TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEP 465
Query: 1046 VPTPEE---PTSPAAAVPTPEE----------PTSPAAAVPTPEEPTSPAAAVPTPEEPT 1092
PT + PT+P PT + PT+ +A TP+EP+ P P P
Sbjct: 466 APTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK 525
Query: 1093 SPAAAVPTPEEPTSPAAAVP-TPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVP 1151
PA P PT+P P TP+EPA P P P PA P P P P
Sbjct: 526 EPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTP 585
Query: 1152 -TPEESASAAVAVP---TPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPT--- 1204
TPE+ A P TPEE A PTP A P +P PT
Sbjct: 586 TTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPK 645
Query: 1205 -PAAMVATLEEFTSPAASVPTSEE---PASL-AAAVSNPEEPTSPAAAVPTLEEPTSSAA 1259
PA T+P + PT+ + P +L A + P++P A T +EPTS+
Sbjct: 646 EPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTC 705
Query: 1260 ---AVLTPEELSSPAASVPTPEEPASPA------AAVSNLEEPASPAAAVPTPEVAAIPA 1310
A TP+ + P P P PA A + L+EPA P P+ A
Sbjct: 706 DKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 765
Query: 1311 ASVPTPEVPAIPAAAVPPMEEVSPIGVPFLGVSAHTDSVPISEEGTPVLEEASSTGMWIK 1370
PT PA P +E +P + P + E P ST K
Sbjct: 766 TKGPTSTTSDKPAPTTP--KETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTK 823
Query: 1371 E 1371
E
Sbjct: 824 E 824
Score = 119 bits (298), Expect = 2e-26
Identities = 117/418 (27%), Positives = 165/418 (39%), Gaps = 55/418 (13%)
Query: 965 TEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEE-----PTSPAAA 1019
T++ TP+ PV A D +V+TP+ + V T + P +P +
Sbjct: 167 TKKKPTPKPPVVD----EAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPS 222
Query: 1020 VPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE-- 1077
+P P TS ++ +E T T + TS T + + + ++
Sbjct: 223 LP-PNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLA 281
Query: 1078 PTSPAAAVPTPE-EPTSPAAAVPTPEEPT-----SPAAAVPTPEEPASPAAAVPTPEEPA 1131
PTS A PTP+ E T+ A+ TP+EPT PA+ P P + +A TP+EPA
Sbjct: 282 PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA 341
Query: 1132 --SPAAAVPTPEEPA---FPAPAVPTPEESASAAVAVPTPEESAS-------PAAAVP-- 1177
+ +A TP+EPA PA TP+E A P P + S PA P
Sbjct: 342 PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 401
Query: 1178 ----TPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTS-------- 1225
TP E A T P PA + PA T+P PT+
Sbjct: 402 PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT 461
Query: 1226 -EEPASLAAAVSNPEEPTSPA-----AAVPTLEE--PTSSAAAVLTPEELSSPAASVPTP 1277
+EPA +P P PA +A T +E PT++ +A TP+E S P P
Sbjct: 462 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 521
Query: 1278 EEPASPAAAVSNLEEPASPAAAVP-TPEVAAIPAASVPTPEVPAIPAAAVPPMEEVSP 1334
P PA P +P P TP+ A P P P PA P +E +P
Sbjct: 522 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP--KETAP 577
Score = 104 bits (259), Expect = 7e-22
Identities = 119/473 (25%), Positives = 171/473 (36%), Gaps = 52/473 (10%)
Query: 841 PTVKDALDAALPSPEEGT-SIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEEEDVTAA 899
PT + L A +PEE T + PAP A P +E T
Sbjct: 601 PTTPEEL--APTTPEEPTPTTPEEPAPTTPKAAAPNTP--------------KEPAPTTP 644
Query: 900 AVSAPERATVPAVTV------SVPEGTAAVA----AVSSPEETAPAVAAAITQEGMSAVA 949
AP PA T + P+GTA A ++P++ AP A T + ++
Sbjct: 645 KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 704
Query: 950 GFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRV-STPEEPASPAAAVP 1008
P T P T ++ P P PA T P T +TP++PA A
Sbjct: 705 CDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 764
Query: 1009 TPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSP 1068
T + PTS + P P P A P P PA P PT+P PT E ++P
Sbjct: 765 TTKGPTSTTSDKPAPTTPKETA-----PTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTP 819
Query: 1069 AAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPE 1128
T +EPT+ +P+E T +A PTP+ A +P+EP P P
Sbjct: 820 T----TTKEPTT---IHKSPDESTPELSAEPTPK------ALENSPKEPGVPTTKTPAAT 866
Query: 1129 EP-ASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAA 1187
+P + A T E P T + A T + + S A T S +
Sbjct: 867 KPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQD 926
Query: 1188 VV---ATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSP 1244
T + T+ A V T + T E P + + + A P++PT
Sbjct: 927 TTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTK- 985
Query: 1245 AAAVPTLEEPTSSAAAVLTPEELSSPAASVPT-PEEPASPAAAVSNLEEPASP 1296
A PT + + V P+ +P T PE + A + L+ P
Sbjct: 986 APKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRP 1038
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 173 bits (438), Expect = 1e-42
Identities = 167/627 (26%), Positives = 222/627 (35%), Gaps = 66/627 (10%)
Query: 810 PEKQVTKAGNTEPVLEEWIPVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGT 869
P TK+ T P +E P ++ A T K+ P T+ +A P+
Sbjct: 381 PAPTTTKSAPTTP--KEPAPTT---TKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP 435
Query: 870 AVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSP 929
A P P + +E T P PA T P T P
Sbjct: 436 APTTPKKPAP---------TTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP----KEP 482
Query: 930 EETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTP----EGPVT-----PATT 980
TAP A T + + P P T ++ P P T P TT
Sbjct: 483 APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 542
Query: 981 VHAP---EEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPT-PEEPTSPAAAVPPP 1036
AP +EP + P P PA P PT+P PT P+EP P P
Sbjct: 543 KSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAP 602
Query: 1037 EEPTSPAAAVPTPEEPTSPAAAVPTPEE---PTSPAAAVPT-PEE--PTSPAAAVPT-PE 1089
P PA P PT+P PT E PT+P PT PEE PT+P PT PE
Sbjct: 603 TTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPE 662
Query: 1090 EP--TSPAAAVP-TPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTP-EEPAF 1145
EP T+P AA P TP+EP P P P PA P P +P PT +EPA
Sbjct: 663 EPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAP 722
Query: 1146 PAPAVPTPEESASAAVAVPTPEESASPAAAVPT-----------------PAESASFAAV 1188
P P P+E A PT PA P PA +
Sbjct: 723 TTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTA 782
Query: 1189 VATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAV 1248
TL+EP P P + T T+ + TS++PA + P P PA
Sbjct: 783 PTTLKEPAPTTPKKPAPKELAPT----TTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTT 838
Query: 1249 PTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAI 1308
P PT+ T E+S+P + SP + L +P A +P+ +
Sbjct: 839 PKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGV 898
Query: 1309 PAASVPTPEVPAIPAAAVPPMEEVSPIGVPFLGVSA---HTDSVPISEEGTPVLEEASST 1365
P P P + A E P +A ++ +E+ T A++T
Sbjct: 899 PTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTT 958
Query: 1366 GMWIKEDLDSLVFGIKEVTSTVLHGKV 1392
+ D+ F I + +T L KV
Sbjct: 959 QVTSTTTQDTTPFKITTLKTTTLAPKV 985
Score = 168 bits (425), Expect = 4e-41
Identities = 164/601 (27%), Positives = 220/601 (36%), Gaps = 76/601 (12%)
Query: 811 EKQVTKAGNTEPVLEEWIPVLQRPSRTAAVPTVKDALDA---ALPSPEEGTSIAAVPAPE 867
+++ T A T+ + + L S+ A PT K AL +P+E P P
Sbjct: 301 KEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKE-------PTPT 353
Query: 868 GTAVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVS 927
A+ P + S + +E SAP PA T T A +
Sbjct: 354 TPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPT------TTKEPAPT 407
Query: 928 SPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEP 987
+P+E AP T+E + P T ++ P P PA T P+EP
Sbjct: 408 TPKEPAPTT----TKEPAPTTTK----------SAPTTPKEPAPTTPKKPAPTT--PKEP 451
Query: 988 DTAAVRVSTPEEP--ASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAA 1045
+TP+EP +P PT +EP P P P PA P PT+P
Sbjct: 452 AP-----TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEP 506
Query: 1046 VPTPEE---PTSPAAAVPTPEE----------PTSPAAAVPTPEEPTSPAAAVPTPEEPT 1092
PT + PT+P PT + PT+ +A TP+EP+ P P P
Sbjct: 507 APTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK 566
Query: 1093 SPAAAVPTPEEPTSPAAAVP-TPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVP 1151
PA P PT+P P TP+EPA P P P PA P P P P
Sbjct: 567 EPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTP 626
Query: 1152 -TPEESASAAVAVP---TPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPT--- 1204
TPE+ A P TPEE A PTP A P +P PT
Sbjct: 627 TTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPK 686
Query: 1205 -PAAMVATLEEFTSPAASVPTSEE---PASL-AAAVSNPEEPTSPAAAVPTLEEPTSSAA 1259
PA T+P + PT+ + P +L A + P++P A T +EPTS+
Sbjct: 687 EPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTC 746
Query: 1260 ---AVLTPEELSSPAASVPTPEEPASPA------AAVSNLEEPASPAAAVPTPEVAAIPA 1310
A TP+ + P P P PA A + L+EPA P P+ A
Sbjct: 747 DKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 806
Query: 1311 ASVPTPEVPAIPAAAVPPMEEVSPIGVPFLGVSAHTDSVPISEEGTPVLEEASSTGMWIK 1370
PT PA P +E +P + P + E P ST K
Sbjct: 807 TKGPTSTTSDKPAPTTP--KETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTK 864
Query: 1371 E 1371
E
Sbjct: 865 E 865
Score = 119 bits (298), Expect = 2e-26
Identities = 117/418 (27%), Positives = 165/418 (39%), Gaps = 55/418 (13%)
Query: 965 TEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEE-----PTSPAAA 1019
T++ TP+ PV A D +V+TP+ + V T + P +P +
Sbjct: 208 TKKKPTPKPPVVD----EAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPS 263
Query: 1020 VPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE-- 1077
+P P TS ++ +E T T + TS T + + + ++
Sbjct: 264 LP-PNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLA 322
Query: 1078 PTSPAAAVPTPE-EPTSPAAAVPTPEEPT-----SPAAAVPTPEEPASPAAAVPTPEEPA 1131
PTS A PTP+ E T+ A+ TP+EPT PA+ P P + +A TP+EPA
Sbjct: 323 PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA 382
Query: 1132 --SPAAAVPTPEEPA---FPAPAVPTPEESASAAVAVPTPEESAS-------PAAAVP-- 1177
+ +A TP+EPA PA TP+E A P P + S PA P
Sbjct: 383 PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 442
Query: 1178 ----TPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTS-------- 1225
TP E A T P PA + PA T+P PT+
Sbjct: 443 PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT 502
Query: 1226 -EEPASLAAAVSNPEEPTSPA-----AAVPTLEE--PTSSAAAVLTPEELSSPAASVPTP 1277
+EPA +P P PA +A T +E PT++ +A TP+E S P P
Sbjct: 503 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 562
Query: 1278 EEPASPAAAVSNLEEPASPAAAVP-TPEVAAIPAASVPTPEVPAIPAAAVPPMEEVSP 1334
P PA P +P P TP+ A P P P PA P +E +P
Sbjct: 563 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP--KETAP 618
Score = 104 bits (259), Expect = 7e-22
Identities = 119/473 (25%), Positives = 171/473 (36%), Gaps = 52/473 (10%)
Query: 841 PTVKDALDAALPSPEEGT-SIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEEEDVTAA 899
PT + L A +PEE T + PAP A P +E T
Sbjct: 642 PTTPEEL--APTTPEEPTPTTPEEPAPTTPKAAAPNTP--------------KEPAPTTP 685
Query: 900 AVSAPERATVPAVTV------SVPEGTAAVA----AVSSPEETAPAVAAAITQEGMSAVA 949
AP PA T + P+GTA A ++P++ AP A T + ++
Sbjct: 686 KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 745
Query: 950 GFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRV-STPEEPASPAAAVP 1008
P T P T ++ P P PA T P T +TP++PA A
Sbjct: 746 CDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 805
Query: 1009 TPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSP 1068
T + PTS + P P P A P P PA P PT+P PT E ++P
Sbjct: 806 TTKGPTSTTSDKPAPTTPKETA-----PTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTP 860
Query: 1069 AAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPE 1128
T +EPT+ +P+E T +A PTP+ A +P+EP P P
Sbjct: 861 T----TTKEPTT---IHKSPDESTPELSAEPTPK------ALENSPKEPGVPTTKTPAAT 907
Query: 1129 EP-ASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAA 1187
+P + A T E P T + A T + + S A T S +
Sbjct: 908 KPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQD 967
Query: 1188 VV---ATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSP 1244
T + T+ A V T + T E P + + + A P++PT
Sbjct: 968 TTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTK- 1026
Query: 1245 AAAVPTLEEPTSSAAAVLTPEELSSPAASVPT-PEEPASPAAAVSNLEEPASP 1296
A PT + + V P+ +P T PE + A + L+ P
Sbjct: 1027 APKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRP 1079
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 144 bits (363), Expect = 6e-34
Identities = 115/376 (30%), Positives = 146/376 (38%), Gaps = 57/376 (15%)
Query: 974 PVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEE---------PTSPAAAVPTPE 1024
P P+T + P+ P + P P P A +P P P P A +P P
Sbjct: 889 PTLPSTAI--PQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPP- 945
Query: 1025 EPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAA 1084
P P AA+PPP P P A +P P P P A +P P P P A +P P P P A
Sbjct: 946 -PPLPGAAIPPP--PPLPGAGIPLP--PPLPGAGIPPP--PPLPGAGIPPP--PPLPGAG 996
Query: 1085 VPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPA 1144
+P P P P A +P P P P A +P P P P A +P P P P A +P P P
Sbjct: 997 IPPP--PPLPGAGIPPP--PPLPGAGIPPP--PPLPGAGIPPP--PPLPGAGIPPP--PP 1046
Query: 1145 FPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPT 1204
P +P P A + P P P A +P P P P A +P
Sbjct: 1047 LPGAGIPPPPPLPGAGIPPPPP----LPGAGIPPPPPLPG----AGIPPPPPLPGAGIPP 1098
Query: 1205 PAAM--VATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVL 1262
P + V P A +P P L A P P P A +P P V
Sbjct: 1099 PPPLPGVGIPPPPPLPGAGIPP---PPPLPGA-GIPPPPPLPGAGIP----PPPPLPRVG 1150
Query: 1263 TPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIP 1322
P P A +P P P P A + P P V P +P +P P P +P
Sbjct: 1151 IPPPPPLPGAGIPPP--PPLPGAGIP----PPPPLPGVGIPPPPPLPGVGIPPP--PPLP 1202
Query: 1323 AAAVPPMEEVSPIGVP 1338
A +PP + +G+P
Sbjct: 1203 GAGIPPPPPLPGMGIP 1218
Score = 129 bits (325), Expect = 2e-29
Identities = 119/429 (27%), Positives = 152/429 (35%), Gaps = 82/429 (19%)
Query: 908 TVPAV-TVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITE 966
TVP + + ++P+ P P A I AG P +P
Sbjct: 887 TVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILP--------LPPLP 938
Query: 967 EDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEP 1026
G P P P + P A + P P P A +P P P P A +P P P
Sbjct: 939 GAGIPPPPPLPGAAIPPPPPLPGAGI----PLPPPLPGAGIPPP--PPLPGAGIPPP--P 990
Query: 1027 TSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVP 1086
P A +PPP P P A +P P P P A +P P P P A +P P P P A +P
Sbjct: 991 PLPGAGIPPP--PPLPGAGIPPP--PPLPGAGIPPP--PPLPGAGIPPP--PPLPGAGIP 1042
Query: 1087 TPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFP 1146
P P P A +P P P P A +P P P P A +P P P P A +P P P P
Sbjct: 1043 PP--PPLPGAGIPPP--PPLPGAGIPPP--PPLPGAGIPPP--PPLPGAGIPPP--PPLP 1092
Query: 1147 APAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPA 1206
+P P + P P P A +P P P P A +P P
Sbjct: 1093 GAGIPPPPPLPGVGIPPPPP----LPGAGIPPP---------------PPLPGAGIPPPP 1133
Query: 1207 AMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEE 1266
+ P A +P P V P P P A +P P A + P
Sbjct: 1134 PL---------PGAGIP----PPPPLPRVGIPPPPPLPGAGIPP--PPPLPGAGIPPPPP 1178
Query: 1267 LSS-------PAASVPTPEEPASPAAAVS------NLEEPASPAAAVPTPEVAAIPAASV 1313
L P V P P P A + + P +PA +P P P +
Sbjct: 1179 LPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLL 1238
Query: 1314 PTPEVPAIP 1322
P P +P
Sbjct: 1239 PVSGPPLLP 1247
Score = 109 bits (272), Expect = 2e-23
Identities = 113/445 (25%), Positives = 154/445 (34%), Gaps = 97/445 (21%)
Query: 952 SPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAV-------RVSTPEEPASPA 1004
SP +T+P DG P P P P+ + + R+S + P
Sbjct: 747 SPTEEGGVLTLPPV--DGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPT 804
Query: 1005 AAVPTPEEPTS---------PAAAVP---TPEEPTSPAAAV------------PPPEEPT 1040
++ P P S P + P + E TS +V PPP T
Sbjct: 805 QSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCT 864
Query: 1041 SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVP-----------TPEEPTSPAAAVPTPE 1089
++++P P +P PT P+ A+P P P P A +P P
Sbjct: 865 ESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPP 924
Query: 1090 E---------PTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTP 1140
P P A +P P P P AA+P P P P A +P P P P A +P P
Sbjct: 925 PLPGAGILPLPPLPGAGIPPP--PPLPGAAIPPP--PPLPGAGIPLP--PPLPGAGIPPP 978
Query: 1141 EEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAA 1200
P P +P P A + P P P A +P P P P A
Sbjct: 979 --PPLPGAGIPPPPPLPGAGIPPPPP----LPGAGIPPPPPLPG----AGIPPPPPLPGA 1028
Query: 1201 SVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAA 1260
+P P + P A +P P P P P A +P P A
Sbjct: 1029 GIPPPPPL---------PGAGIP----PPPPLPGAGIPPPPPLPGAGIP--PPPPLPGAG 1073
Query: 1261 VLTPEELSSPAASVPTPE-------EPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASV 1313
+ P L P A +P P P P V P P A +P P +P A +
Sbjct: 1074 IPPPPPL--PGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPP--PPLPGAGI 1129
Query: 1314 PTPEVPAIPAAAVPPMEEVSPIGVP 1338
P P P +P A +PP + +G+P
Sbjct: 1130 PPP--PPLPGAGIPPPPPLPRVGIP 1152
Score = 95.9 bits (237), Expect = 2e-19
Identities = 70/220 (31%), Positives = 88/220 (40%), Gaps = 33/220 (15%)
Query: 969 GTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTS 1028
G P P P + P A + P P P A +P P P P +P P P
Sbjct: 1062 GIPPPPPLPGAGIPPPPPLPGAGI----PPPPPLPGAGIPPP--PPLPGVGIPPP--PPL 1113
Query: 1029 PAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTP 1088
P A +PPP P P A +P P P P A +P P P P +P P P P A +P P
Sbjct: 1114 PGAGIPPP--PPLPGAGIPPP--PPLPGAGIPPP--PPLPRVGIPPP--PPLPGAGIPPP 1165
Query: 1089 EEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEE------ 1142
P P A +P P P P +P P P P +P P P P A +P P
Sbjct: 1166 --PPLPGAGIPPP--PPLPGVGIPPP--PPLPGVGIPPP--PPLPGAGIPPPPPLPGMGI 1217
Query: 1143 PAFPAPAVPTPEESASAAVAVPTPEESASP---AAAVPTP 1179
P PAP +P P +P P ++ +PTP
Sbjct: 1218 PPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTP 1257
Score = 72.4 bits (176), Expect = 3e-12
Identities = 56/184 (30%), Positives = 73/184 (39%), Gaps = 31/184 (16%)
Query: 969 GTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTS 1028
G P P P + P A + P P P +P P P P A +P P P
Sbjct: 1117 GIPPPPPLPGAGIPPPPPLPGAGI----PPPPPLPRVGIPPP--PPLPGAGIPPP--PPL 1168
Query: 1029 PAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTP 1088
P A +PPP P P +P P P P +P P P P A +P P P P +P
Sbjct: 1169 PGAGIPPP--PPLPGVGIPPP--PPLPGVGIPPP--PPLPGAGIPPP--PPLPGMGIP-- 1218
Query: 1089 EEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAP 1148
PA A P P P +P P P P + P P ++ +PTP+ F P
Sbjct: 1219 -----PAPAPPLP----PPGTGIPPP--PLLPVSGPPL--LPQVGSSTLPTPQVCGFLPP 1265
Query: 1149 AVPT 1152
+P+
Sbjct: 1266 PLPS 1269
Score = 55.8 bits (133), Expect = 3e-07
Identities = 60/217 (27%), Positives = 83/217 (38%), Gaps = 27/217 (12%)
Query: 983 APEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSP 1042
AP PDT + + P S AA P++P SP +P E P+ PAA + P+S
Sbjct: 263 APGSPDTEQALSALSDLPESLAAEPREPQQPPSP-GGLPVSEAPSLPAAQPAAKDSPSS- 320
Query: 1043 AAAVPTPEE-PTSPAAAVP------TPEEPTSPA---AAVPTPEEPTSPAAAVPTP---- 1088
A P PE P AA P T EE A A +P E +P P
Sbjct: 321 -TAFPFPEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLG 379
Query: 1089 EEPTSPAAAVPTPEEPTSPAAAVPT-----PEEPASPAAAVPTPEEPASP-----AAAVP 1138
EEP A P + P + P+ P +P T + +SP +
Sbjct: 380 EEPEEEAQGPDAPAAASLPGSPAPSQRCFKPYPLITPCYIKTTTRQLSSPNHSPSQSPNQ 439
Query: 1139 TPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAA 1175
+P P P++ +A A+VA P + A A
Sbjct: 440 SPRIKRRPEPSLSRGSRTALASVAAPAKKHRADGGLA 476
Score = 48.5 bits (114), Expect = 5e-05
Identities = 70/261 (26%), Positives = 95/261 (36%), Gaps = 37/261 (14%)
Query: 1050 EEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAA-AVPTPEEPTSPAAAVPTPEEPTSPA 1108
EEP +P AV +P+ P A + P+ A P P + A + P S A
Sbjct: 230 EEPAAPPTAV-SPQ----PGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLA 284
Query: 1109 AAVPTPEEPASPAAAVPTPEEPASPAA---AVPTPEEPAFPAPAVPTPEESASAAV--AV 1163
A P++P SP +P E P+ PAA A +P AFP P EE+A A V A
Sbjct: 285 AEPREPQQPPSPGG-LPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAG 343
Query: 1164 PTPEESASPA-AAVPTPAESASFAAVVA------TLEEPTSPAASVPTPAAMVATLEEFT 1216
T EE A P + +A V EEP A PA
Sbjct: 344 DTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQGPDAPA---------- 393
Query: 1217 SPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPT 1276
AAS+P S P+ P L P S P + + + +
Sbjct: 394 --AASLPGSPAPSQRCFKPYPLITPCYIKTTTRQLSSPNHS------PSQSPNQSPRIKR 445
Query: 1277 PEEPASPAAAVSNLEEPASPA 1297
EP+ + + L A+PA
Sbjct: 446 RPEPSLSRGSRTALASVAAPA 466
Score = 35.0 bits (79), Expect = 0.52
Identities = 33/113 (29%), Positives = 46/113 (40%), Gaps = 16/113 (14%)
Query: 1193 EEPTSPAASV-PTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTL 1251
EEP +P +V P P A + P+ E P S P + A
Sbjct: 230 EEPAAPPTAVSPQPGAFLGLDRFLLGPSGGA--GEAPGS----------PDTEQALSALS 277
Query: 1252 EEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPE 1304
+ P S AA P++ SP +P E P+ PAA + + P+S A P PE
Sbjct: 278 DLPESLAAEPREPQQPPSPGG-LPVSEAPSLPAAQPAAKDSPSS--TAFPFPE 327
Score = 32.7 bits (73), Expect = 2.6
Identities = 28/101 (27%), Positives = 38/101 (37%), Gaps = 5/101 (4%)
Query: 1239 EEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAA 1298
EEP +P PT P A L L + P P + A + + P S AA
Sbjct: 230 EEPAAP----PTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAA 285
Query: 1299 AVPTPEVAAIPAASVPTPEVPAIPAAAVPPMEEVSPIGVPF 1339
P+ P +P E P++PAA + S PF
Sbjct: 286 EPREPQQPPSPGG-LPVSEAPSLPAAQPAAKDSPSSTAFPF 325
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 137 bits (344), Expect = 1e-31
Identities = 90/376 (23%), Positives = 133/376 (35%), Gaps = 32/376 (8%)
Query: 974 PVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAV 1033
P P TT P T +TP P + P P+ P TP T+P+ +
Sbjct: 1399 PSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPI 1458
Query: 1034 -----PPPEEPTSPAAAVPTPEE--PTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVP 1086
PPP SP P+P P+ P TP T+P+ TP P + +P
Sbjct: 1459 STTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLP 1518
Query: 1087 TPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFP 1146
P+ P TP T+P+ TP P + +P P+ P TP P
Sbjct: 1519 PTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTP 1578
Query: 1147 APAVPTPEESASAAVAVPTPEESASPAAAVPT--PAESASFAAVVATLEEPTSPAASVPT 1204
+P T + P P + SP T P + + PTS PT
Sbjct: 1579 SPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPT 1638
Query: 1205 -----PAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAA 1259
P T T+P S PT+ P+ + P T+P++ + T P
Sbjct: 1639 TTPSPPPTTTTTPPPTTTP--SPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSP----- 1691
Query: 1260 AVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVP 1319
P ++ TP +P++ ++ P+S P P P+ + TP P
Sbjct: 1692 ----------PTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTT-TPSPP 1740
Query: 1320 AIPAAAVPPMEEVSPI 1335
+PP SP+
Sbjct: 1741 TTTMTTLPPTTTSSPL 1756
Score = 129 bits (323), Expect = 3e-29
Identities = 89/369 (24%), Positives = 137/369 (37%), Gaps = 21/369 (5%)
Query: 970 TPEGPVTPATTVHAPEEPDTAAVRVSTPEE---PASPAAAVPTPEEPTSPAAAVPTPEEP 1026
TP P T TT P +TP P+ P + TP T+P+ TP P
Sbjct: 1421 TPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPP 1480
Query: 1027 TS----PAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPA 1082
T+ P P T+P+ TP P + +P P+ P TP T+P+
Sbjct: 1481 TTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPS 1540
Query: 1083 AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEE 1142
TP P + +P P+ P TP +P+ PT P+ P TP
Sbjct: 1541 PPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSP--PTTTTPSPPTITTTTPPP 1598
Query: 1143 PAFPAP-----AVPTPEESASAAVAVP-TPEESASPAAAVPTPAESASFAAVVATLEEPT 1196
P+P P P + S P TP S + TP+ + P+
Sbjct: 1599 TTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPS 1658
Query: 1197 SPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTS 1256
P + P+P T T+ +S P + P+ ++ P T+P++ + T P+S
Sbjct: 1659 PPTTTTPSPPITTTTTPPPTTTPSS-PITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSS 1717
Query: 1257 SAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPA---ASV 1313
+ P +++P+ + TP P + + +SP P P P S
Sbjct: 1718 TTTPSPPPTTMTTPSPTT-TPSPPTTTMTTLPP-TTTSSPLTTTPLPPSITPPTFSPFST 1775
Query: 1314 PTPEVPAIP 1322
TP P +P
Sbjct: 1776 TTPTTPCVP 1784
Score = 118 bits (295), Expect = 5e-26
Identities = 80/351 (22%), Positives = 127/351 (36%), Gaps = 36/351 (10%)
Query: 1014 TSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAV------PTPEEPTS 1067
T+P+ TP P + +PP P+ P TP T+P+ + P P+
Sbjct: 1397 TTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSP 1456
Query: 1068 PAAAVPTPEEPTSPAAAVPTPEEPTS----PAAAVPTPEEPTSPAAAVPTPEEPASPAAA 1123
P + TP T+P+ TP PT+ P TP T+P+ TP P +
Sbjct: 1457 PISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTT 1516
Query: 1124 VPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESA 1183
+P P+ P TP P+P TP ++ +P + P TP +
Sbjct: 1517 LPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTT 1576
Query: 1184 SFAAVVATLEEPTSPAASVPTPAAMVATLEEFT---SPAASVPTSEEPASL-AAAVSNPE 1239
+ P+ P + P+P + T T SP + T+ P + + + P
Sbjct: 1577 T----------PSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPI 1626
Query: 1240 EPTSPAAAVPTLEEPTSSAAAVLTPEELSSPA-ASVPTPEEPASPAAAVSNLEEPASPAA 1298
P + +P P+ TP ++P+ + TP P + P+SP
Sbjct: 1627 TPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPIT 1686
Query: 1299 AVP--------TPEVAAIPAASVPTPEVPAIPAAAVPP---MEEVSPIGVP 1338
P TP P++ + T P+ PP M SP P
Sbjct: 1687 TTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTP 1737
Score = 115 bits (288), Expect = 3e-25
Identities = 91/394 (23%), Positives = 142/394 (36%), Gaps = 33/394 (8%)
Query: 908 TVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEE 967
T+P T P T + P T P+ T SP + P T
Sbjct: 1415 TLPPTTTPSPPTTTTT---TPPPTTTPSPPITTTTTPPPTTTP-SPPISTTTTPPPTTTP 1470
Query: 968 DG---TPEGPVT----PATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAV 1020
TP P T P TT P T + +TP P + +P P+ P
Sbjct: 1471 SPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTT 1530
Query: 1021 PTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAA-AVPTPEEPT 1079
TP T+P+ P P + +P P+ P TP T+P+ TP PT
Sbjct: 1531 TTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPT 1590
Query: 1080 SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPT 1139
P P+ P TP T+P+ TP P + +P P+ P T
Sbjct: 1591 ITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTT 1650
Query: 1140 PEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPT-PAESASFAAVVATLEEPTSP 1198
P P+P PT + TP + +P++ + T P+ + + P+SP
Sbjct: 1651 PPPTTTPSP--PTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSP 1708
Query: 1199 AASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSA 1258
+ TP++ SP + T+ P + P PT+ +P PT+++
Sbjct: 1709 ITTTTTPSSTTT-----PSPPPTTMTTPSP------TTTPSPPTTTMTTLP----PTTTS 1753
Query: 1259 AAVLT---PEELSSPAASVPTPEEPASPAAAVSN 1289
+ + T P ++ P S + P +P + N
Sbjct: 1754 SPLTTTPLPPSITPPTFSPFSTTTPTTPCVPLCN 1787
Score = 108 bits (271), Expect = 3e-23
Identities = 118/522 (22%), Positives = 167/522 (31%), Gaps = 62/522 (11%)
Query: 858 TSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVP 917
T++ P P GT P ++ T + P T P
Sbjct: 3837 TTVTPTPTPTGTQT-----PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3891
Query: 918 EGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTP 977
GT ++P T V T G +P + T +T TP G TP
Sbjct: 3892 TGTQT--PTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTP-TPTGTQTP 3943
Query: 978 ATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPE-------EPTSPA 1030
TT P T V+ P TP T+ PTP P +
Sbjct: 3944 TTT------PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3997
Query: 1031 AAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE 1090
V P PT TP T+ PTP +P TP T+ PTP
Sbjct: 3998 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT---TPITTTTTVTPTPTPTG 4054
Query: 1091 PTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAV 1150
+P TP T+ PTP +P TP + PTP P
Sbjct: 4055 TQTPTT---TPITTTTTVTPTPTPTGTQTPTT---TPITTTTTVTPTPTPTGTQTPTT-- 4106
Query: 1151 PTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVA 1210
TP + + PTP + +P TP + + T PT TP
Sbjct: 4107 -TPITTTTTVTPTPTPTGTQTPTT---TPITTTTTVTPTPT---PTGTQTPTTTPITTTT 4159
Query: 1211 TLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSP 1270
T+ +P + + P + V+ PT PT ++ A + S+P
Sbjct: 4160 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTG-----PPTHTSTAPIAELTTSNP 4214
Query: 1271 AASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIPAA----AV 1326
TP+ S + S L E + + +P P + A TP P + +
Sbjct: 4215 PPESSTPQTSRSTS---SPLTESTTLLSTLP-PAIEMTSTAPPSTPTAPTTTSGGHTLSP 4270
Query: 1327 PPMEEVSPIGVPFLGVSAHTDSVPISEEGTPVLEEASSTGMW 1368
PP SP G P G + + S P TP + ++T W
Sbjct: 4271 PPSTTTSPPGTPTRGTTTGSSSAP-----TPSTVQTTTTSAW 4307
Score = 105 bits (261), Expect = 4e-22
Identities = 117/544 (21%), Positives = 165/544 (30%), Gaps = 53/544 (9%)
Query: 858 TSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVP 917
T++ P P GT P ++ T + P T P
Sbjct: 3745 TTVTPTPTPTGTQT-----PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3799
Query: 918 EGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTP 977
GT ++P T V T G +P + T +T TP G TP
Sbjct: 3800 TGTQT--PTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTP-TPTGTQTP 3851
Query: 978 ATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPE-------EPTSPA 1030
TT P T V+ P TP T+ PTP P +
Sbjct: 3852 TTT------PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3905
Query: 1031 AAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE 1090
V P PT TP T+ PTP +P TP T+ PTP
Sbjct: 3906 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT---TPITTTTTVTPTPTPTG 3962
Query: 1091 PTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAV 1150
+P TP T+ PTP +P TP + PTP P
Sbjct: 3963 TQTPTT---TPITTTTTVTPTPTPTGTQTPTT---TPITTTTTVTPTPTPTGTQTPTT-- 4014
Query: 1151 PTPEESASAAVAVPTPEESASPAAA--------VPTPAESASFAAVVATLEEPTSPAASV 1202
TP + + PTP + +P PTP + + + T+
Sbjct: 4015 -TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-VTPT 4072
Query: 1203 PTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVL 1262
PTP + +V + P + P T+ PT PT +
Sbjct: 4073 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---PTGTQTPTT 4129
Query: 1263 TPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIP 1322
TP ++ PTP +P +P PTP P + T P
Sbjct: 4130 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTP 4186
Query: 1323 AAAVPPMEEVSPIGVPFLGVSAHTDSVPISEEGTPVLEEASSTGMWIKEDLDSLVFGIKE 1382
+ P ++ T S P E TP ++S+ + L S + E
Sbjct: 4187 TPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIE 4246
Query: 1383 VTST 1386
+TST
Sbjct: 4247 MTST 4250
Score = 100 bits (250), Expect = 8e-21
Identities = 79/342 (23%), Positives = 114/342 (33%), Gaps = 42/342 (12%)
Query: 1020 VPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPT 1079
+ TP PT+ + PP T P P+P PT T P P+P P
Sbjct: 1396 ITTPSPPTTTPSP-PPTSTTTLPPTTTPSP----------PTTTTTTPPPTTTPSP--PI 1442
Query: 1080 SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPT 1139
+ P P+ P + TP T+P+ TP SP P+P P T
Sbjct: 1443 TTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTP----SPPTTTPSP-----PTTTTTT 1493
Query: 1140 PEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPA 1199
P P+P TP ++ +P + P TP + + P+ P
Sbjct: 1494 PPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTT----------PSPPT 1543
Query: 1200 ASVPTPAAMVATLEEFTSPAASVPTSEEPASLAA----AVSNPEEPTSPAAAVPTLEEPT 1255
+ TP TL T+P+ T+ P + P PT P P+
Sbjct: 1544 TTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPS 1603
Query: 1256 SSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPT 1315
TP ++P+ TP P + + P+ P TP P+ T
Sbjct: 1604 PPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTT 1663
Query: 1316 PEVPAIPAAAVPPMEEVSPIGVPFLGVSAHTDSVPISEEGTP 1357
P I PP P P ++ T S P + TP
Sbjct: 1664 TPSPPITTTTTPP-----PTTTPSSPITT-TPSPPTTTMTTP 1699
Score = 97.8 bits (242), Expect = 6e-20
Identities = 108/516 (20%), Positives = 156/516 (30%), Gaps = 47/516 (9%)
Query: 858 TSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVP 917
T++ P P GT P ++ T + P T P
Sbjct: 2043 TTVTPTPTPTGTQT-----PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2097
Query: 918 EGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTP 977
GT ++P T V T G +P + T +T TP G TP
Sbjct: 2098 TGTQT--PTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTP-TPTGTQTP 2149
Query: 978 ATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPE-------EPTSPA 1030
TT P T V+ P TP T+ PTP P +
Sbjct: 2150 TTT------PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2203
Query: 1031 AAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE 1090
V P PT TP T+ PTP +P TP T+ PTP
Sbjct: 2204 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT---TPITTTTTVTPTPTPTG 2260
Query: 1091 PTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAV 1150
+P TP T+ PTP +P TP + PTP P
Sbjct: 2261 TQTPTT---TPITTTTTVTPTPTPTGTQTPTT---TPITTTTTVTPTPTPTGTQTP---T 2311
Query: 1151 PTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVA 1210
TP + + PTP + +P TP + + V PT TP
Sbjct: 2312 TTPITTTTTVTPTPTPTGTQTPTT---TPITTTT---TVTPTPTPTGTQTPTTTPITTTT 2365
Query: 1211 TLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSP 1270
T+ +P + + P + V+ PT T T++ TP +P
Sbjct: 2366 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2425
Query: 1271 AASVPTPEEPASPAAAVSNLEEP-ASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPM 1329
+ T +P + + P +P T P + P V P
Sbjct: 2426 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2485
Query: 1330 EEVSPIGVPFLGVSAHTDSVPISEEGTPVLEEASST 1365
+P G + T + ++ TP + +T
Sbjct: 2486 P--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2519
Score = 97.8 bits (242), Expect = 6e-20
Identities = 108/516 (20%), Positives = 156/516 (30%), Gaps = 47/516 (9%)
Query: 858 TSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVP 917
T++ P P GT P ++ T + P T P
Sbjct: 2273 TTVTPTPTPTGTQT-----PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2327
Query: 918 EGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTP 977
GT ++P T V T G +P + T +T TP G TP
Sbjct: 2328 TGTQT--PTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTP-TPTGTQTP 2379
Query: 978 ATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPE-------EPTSPA 1030
TT P T V+ P TP T+ PTP P +
Sbjct: 2380 TTT------PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2433
Query: 1031 AAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE 1090
V P PT TP T+ PTP +P TP T+ PTP
Sbjct: 2434 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT---TPITTTTTVTPTPTPTG 2490
Query: 1091 PTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAV 1150
+P TP T+ PTP +P TP + PTP P
Sbjct: 2491 TQTPTT---TPITTTTTVTPTPTPTGTQTPTT---TPITTTTTVTPTPTPTGTQTP---T 2541
Query: 1151 PTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVA 1210
TP + + PTP + +P TP + + V PT TP
Sbjct: 2542 TTPITTTTTVTPTPTPTGTQTPTT---TPITTTT---TVTPTPTPTGTQTPTTTPITTTT 2595
Query: 1211 TLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSP 1270
T+ +P + + P + V+ PT T T++ TP +P
Sbjct: 2596 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2655
Query: 1271 AASVPTPEEPASPAAAVSNLEEP-ASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPM 1329
+ T +P + + P +P T P + P V P
Sbjct: 2656 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2715
Query: 1330 EEVSPIGVPFLGVSAHTDSVPISEEGTPVLEEASST 1365
+P G + T + ++ TP + +T
Sbjct: 2716 P--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2749
Score = 97.8 bits (242), Expect = 6e-20
Identities = 108/516 (20%), Positives = 156/516 (30%), Gaps = 47/516 (9%)
Query: 858 TSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVP 917
T++ P P GT P ++ T + P T P
Sbjct: 2503 TTVTPTPTPTGTQT-----PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2557
Query: 918 EGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTP 977
GT ++P T V T G +P + T +T TP G TP
Sbjct: 2558 TGTQT--PTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTP-TPTGTQTP 2609
Query: 978 ATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPE-------EPTSPA 1030
TT P T V+ P TP T+ PTP P +
Sbjct: 2610 TTT------PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2663
Query: 1031 AAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE 1090
V P PT TP T+ PTP +P TP T+ PTP
Sbjct: 2664 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT---TPITTTTTVTPTPTPTG 2720
Query: 1091 PTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAV 1150
+P TP T+ PTP +P TP + PTP P
Sbjct: 2721 TQTPTT---TPITTTTTVTPTPTPTGTQTPTT---TPITTTTTVTPTPTPTGTQTP---T 2771
Query: 1151 PTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVA 1210
TP + + PTP + +P TP + + V PT TP
Sbjct: 2772 TTPITTTTTVTPTPTPTGTQTPTT---TPITTTT---TVTPTPTPTGTQTPTTTPITTTT 2825
Query: 1211 TLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSP 1270
T+ +P + + P + V+ PT T T++ TP +P
Sbjct: 2826 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2885
Query: 1271 AASVPTPEEPASPAAAVSNLEEP-ASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPM 1329
+ T +P + + P +P T P + P V P
Sbjct: 2886 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2945
Query: 1330 EEVSPIGVPFLGVSAHTDSVPISEEGTPVLEEASST 1365
+P G + T + ++ TP + +T
Sbjct: 2946 P--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2979
Score = 97.8 bits (242), Expect = 6e-20
Identities = 108/516 (20%), Positives = 156/516 (30%), Gaps = 47/516 (9%)
Query: 858 TSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVP 917
T++ P P GT P ++ T + P T P
Sbjct: 2733 TTVTPTPTPTGTQT-----PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2787
Query: 918 EGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTP 977
GT ++P T V T G +P + T +T TP G TP
Sbjct: 2788 TGTQT--PTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTP-TPTGTQTP 2839
Query: 978 ATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPE-------EPTSPA 1030
TT P T V+ P TP T+ PTP P +
Sbjct: 2840 TTT------PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2893
Query: 1031 AAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE 1090
V P PT TP T+ PTP +P TP T+ PTP
Sbjct: 2894 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT---TPITTTTTVTPTPTPTG 2950
Query: 1091 PTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAV 1150
+P TP T+ PTP +P TP + PTP P
Sbjct: 2951 TQTPTT---TPITTTTTVTPTPTPTGTQTPTT---TPITTTTTVTPTPTPTGTQTP---T 3001
Query: 1151 PTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVA 1210
TP + + PTP + +P TP + + V PT TP
Sbjct: 3002 TTPITTTTTVTPTPTPTGTQTPTT---TPITTTT---TVTPTPTPTGTQTPTTTPITTTT 3055
Query: 1211 TLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSP 1270
T+ +P + + P + V+ PT T T++ TP +P
Sbjct: 3056 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3115
Query: 1271 AASVPTPEEPASPAAAVSNLEEP-ASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPM 1329
+ T +P + + P +P T P + P V P
Sbjct: 3116 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3175
Query: 1330 EEVSPIGVPFLGVSAHTDSVPISEEGTPVLEEASST 1365
+P G + T + ++ TP + +T
Sbjct: 3176 P--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3209
Score = 97.8 bits (242), Expect = 6e-20
Identities = 108/516 (20%), Positives = 156/516 (30%), Gaps = 47/516 (9%)
Query: 858 TSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVP 917
T++ P P GT P ++ T + P T P
Sbjct: 2963 TTVTPTPTPTGTQT-----PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3017
Query: 918 EGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTP 977
GT ++P T V T G +P + T +T TP G TP
Sbjct: 3018 TGTQT--PTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTP-TPTGTQTP 3069
Query: 978 ATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPE-------EPTSPA 1030
TT P T V+ P TP T+ PTP P +
Sbjct: 3070 TTT------PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3123
Query: 1031 AAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE 1090
V P PT TP T+ PTP +P TP T+ PTP
Sbjct: 3124 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT---TPITTTTTVTPTPTPTG 3180
Query: 1091 PTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAV 1150
+P TP T+ PTP +P TP + PTP P
Sbjct: 3181 TQTPTT---TPITTTTTVTPTPTPTGTQTPTT---TPITTTTTVTPTPTPTGTQTP---T 3231
Query: 1151 PTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVA 1210
TP + + PTP + +P TP + + V PT TP
Sbjct: 3232 TTPITTTTTVTPTPTPTGTQTPTT---TPITTTT---TVTPTPTPTGTQTPTTTPITTTT 3285
Query: 1211 TLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSP 1270
T+ +P + + P + V+ PT T T++ TP +P
Sbjct: 3286 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3345
Query: 1271 AASVPTPEEPASPAAAVSNLEEP-ASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPM 1329
+ T +P + + P +P T P + P V P
Sbjct: 3346 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3405
Query: 1330 EEVSPIGVPFLGVSAHTDSVPISEEGTPVLEEASST 1365
+P G + T + ++ TP + +T
Sbjct: 3406 P--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3439
Score = 97.8 bits (242), Expect = 6e-20
Identities = 108/516 (20%), Positives = 156/516 (30%), Gaps = 47/516 (9%)
Query: 858 TSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVP 917
T++ P P GT P ++ T + P T P
Sbjct: 3193 TTVTPTPTPTGTQT-----PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3247
Query: 918 EGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTP 977
GT ++P T V T G +P + T +T TP G TP
Sbjct: 3248 TGTQT--PTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTP-TPTGTQTP 3299
Query: 978 ATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPE-------EPTSPA 1030
TT P T V+ P TP T+ PTP P +
Sbjct: 3300 TTT------PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3353
Query: 1031 AAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE 1090
V P PT TP T+ PTP +P TP T+ PTP
Sbjct: 3354 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT---TPITTTTTVTPTPTPTG 3410
Query: 1091 PTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAV 1150
+P TP T+ PTP +P TP + PTP P
Sbjct: 3411 TQTPTT---TPITTTTTVTPTPTPTGTQTPTT---TPITTTTTVTPTPTPTGTQTP---T 3461
Query: 1151 PTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVA 1210
TP + + PTP + +P TP + + V PT TP
Sbjct: 3462 TTPITTTTTVTPTPTPTGTQTPTT---TPITTTT---TVTPTPTPTGTQTPTTTPITTTT 3515
Query: 1211 TLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSP 1270
T+ +P + + P + V+ PT T T++ TP +P
Sbjct: 3516 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3575
Query: 1271 AASVPTPEEPASPAAAVSNLEEP-ASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPM 1329
+ T +P + + P +P T P + P V P
Sbjct: 3576 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3635
Query: 1330 EEVSPIGVPFLGVSAHTDSVPISEEGTPVLEEASST 1365
+P G + T + ++ TP + +T
Sbjct: 3636 P--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3669
Score = 97.8 bits (242), Expect = 6e-20
Identities = 108/516 (20%), Positives = 156/516 (30%), Gaps = 47/516 (9%)
Query: 858 TSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVP 917
T++ P P GT P ++ T + P T P
Sbjct: 3423 TTVTPTPTPTGTQT-----PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3477
Query: 918 EGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTP 977
GT ++P T V T G +P + T +T TP G TP
Sbjct: 3478 TGTQT--PTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTP-TPTGTQTP 3529
Query: 978 ATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPE-------EPTSPA 1030
TT P T V+ P TP T+ PTP P +
Sbjct: 3530 TTT------PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3583
Query: 1031 AAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE 1090
V P PT TP T+ PTP +P TP T+ PTP
Sbjct: 3584 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT---TPITTTTTVTPTPTPTG 3640
Query: 1091 PTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAV 1150
+P TP T+ PTP +P TP + PTP P
Sbjct: 3641 TQTPTT---TPITTTTTVTPTPTPTGTQTPTT---TPITTTTTVTPTPTPTGTQTP---T 3691
Query: 1151 PTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVA 1210
TP + + PTP + +P TP + + V PT TP
Sbjct: 3692 TTPITTTTTVTPTPTPTGTQTPTT---TPITTTT---TVTPTPTPTGTQTPTTTPITTTT 3745
Query: 1211 TLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSP 1270
T+ +P + + P + V+ PT T T++ TP +P
Sbjct: 3746 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3805
Query: 1271 AASVPTPEEPASPAAAVSNLEEP-ASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPM 1329
+ T +P + + P +P T P + P V P
Sbjct: 3806 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3865
Query: 1330 EEVSPIGVPFLGVSAHTDSVPISEEGTPVLEEASST 1365
+P G + T + ++ TP + +T
Sbjct: 3866 P--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3899
Score = 97.8 bits (242), Expect = 6e-20
Identities = 108/516 (20%), Positives = 156/516 (30%), Gaps = 47/516 (9%)
Query: 858 TSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVP 917
T++ P P GT P ++ T + P T P
Sbjct: 3653 TTVTPTPTPTGTQT-----PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3707
Query: 918 EGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTP 977
GT ++P T V T G +P + T +T TP G TP
Sbjct: 3708 TGTQT--PTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTP-TPTGTQTP 3759
Query: 978 ATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPE-------EPTSPA 1030
TT P T V+ P TP T+ PTP P +
Sbjct: 3760 TTT------PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3813
Query: 1031 AAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE 1090
V P PT TP T+ PTP +P TP T+ PTP
Sbjct: 3814 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT---TPITTTTTVTPTPTPTG 3870
Query: 1091 PTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAV 1150
+P TP T+ PTP +P TP + PTP P
Sbjct: 3871 TQTPTT---TPITTTTTVTPTPTPTGTQTPTT---TPITTTTTVTPTPTPTGTQTP---T 3921
Query: 1151 PTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVA 1210
TP + + PTP + +P TP + + V PT TP
Sbjct: 3922 TTPITTTTTVTPTPTPTGTQTPTT---TPITTTT---TVTPTPTPTGTQTPTTTPITTTT 3975
Query: 1211 TLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSP 1270
T+ +P + + P + V+ PT T T++ TP +P
Sbjct: 3976 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 4035
Query: 1271 AASVPTPEEPASPAAAVSNLEEP-ASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPM 1329
+ T +P + + P +P T P + P V P
Sbjct: 4036 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 4095
Query: 1330 EEVSPIGVPFLGVSAHTDSVPISEEGTPVLEEASST 1365
+P G + T + ++ TP + +T
Sbjct: 4096 P--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 4129
Score = 97.4 bits (241), Expect = 8e-20
Identities = 86/391 (21%), Positives = 123/391 (31%), Gaps = 21/391 (5%)
Query: 810 PEKQVTKAGNTEPVLEEWIPVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGT 869
P T T P P+ T + P +P S P P T
Sbjct: 1410 PTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTT 1469
Query: 870 AVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSP 929
P P + T + P T +T T SP
Sbjct: 1470 PSPPTTTPSPPTTTPSPPTTTT----TTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSP 1525
Query: 930 EETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVT--PATTVHAPEEP 987
T T +P + T+P T P T P TT P P
Sbjct: 1526 PTTTTTTPPPTTTPSPPTTTPITPPTSTT--TLPPTTTPSPPPTTTTTPPPTT--TPSPP 1581
Query: 988 DTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVP 1047
T +TP P P P+ P TP T+P+ P P + +P
Sbjct: 1582 TT-----TTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLP 1636
Query: 1048 TPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSP 1107
P+ P TP T+P+ PT P+ P TP T+P++ + T P+ P
Sbjct: 1637 PTTTPSPPPTTTTTPPPTTTPSP--PTTTTPSPPITTTTTPPPTTTPSSPITT--TPSPP 1692
Query: 1108 AAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPE 1167
+ TP +P++ + T P+S P P P+P TP + +P P
Sbjct: 1693 TTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTT-TPSPPTTTMTTLP-PT 1750
Query: 1168 ESASPAAAVPTPAESASFAAVVATLEEPTSP 1198
++SP P P + PT+P
Sbjct: 1751 TTSSPLTTTPLPPSITPPTFSPFSTTTPTTP 1781
Score = 97.1 bits (240), Expect = 1e-19
Identities = 111/476 (23%), Positives = 147/476 (30%), Gaps = 50/476 (10%)
Query: 858 TSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVP 917
T++ P P GT P ++ T + P T P
Sbjct: 3883 TTVTPTPTPTGTQT-----PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3937
Query: 918 EGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTP 977
GT ++P T V T G +P + T +T TP G TP
Sbjct: 3938 TGTQT--PTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTP-TPTGTQTP 3989
Query: 978 ATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPE-------EPTSPA 1030
TT P T V+ P TP T+ PTP P +
Sbjct: 3990 TTT------PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 4043
Query: 1031 AAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE 1090
V P PT TP T+ PTP +P TP T+ PTP
Sbjct: 4044 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT---TPITTTTTVTPTPTPTG 4100
Query: 1091 PTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAV 1150
+P TP T+ PTP +P TP + PTP P
Sbjct: 4101 TQTPTT---TPITTTTTVTPTPTPTGTQTPTT---TPITTTTTVTPTPTPTGTQTP---T 4151
Query: 1151 PTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVA 1210
TP + + PTP + +P TP + + V PT PT +
Sbjct: 4152 TTPITTTTTVTPTPTPTGTQTPTT---TPITTTT---TVTPTPTPTGTQTGPPTHTSTAP 4205
Query: 1211 TLEEFTS---PAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEEL 1267
E TS P +S P + S S T P A T P S+ A P
Sbjct: 4206 IAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTA---PTTT 4262
Query: 1268 SSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIPA 1323
S P P SP + S +A P+ +A PTP + P+
Sbjct: 4263 SGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPS 4318
Score = 92.8 bits (229), Expect = 2e-18
Identities = 91/426 (21%), Positives = 129/426 (30%), Gaps = 35/426 (8%)
Query: 960 ITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAA 1019
+T P T T E P P TT P T V+ P TP T+
Sbjct: 1879 VTQPTTMTTTTTENPTPPTTT------PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 1932
Query: 1020 VPTPE-------EPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTP---EEPTSPA 1069
PTP P + V P PT TP T+ PTP + PT+
Sbjct: 1933 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 1992
Query: 1070 AAVPTPEEPTSPAAAVPTPEEP--TSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTP 1127
T PT TP T+ PTP PT TP + PTP
Sbjct: 1993 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQTPTTTPITTTTTVTPTPTP 2051
Query: 1128 EEPASPAAAVPTPEEPAFPAPA-------VPTPEESASAAVAVPTPEESASPAAAVPTPA 1180
+P T P P TP + + PTP + +P TP
Sbjct: 2052 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT---TPI 2108
Query: 1181 ESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEE 1240
+ + V PT TP T+ +P + + P + V+
Sbjct: 2109 TTTT---TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2165
Query: 1241 PTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEP-ASPAAA 1299
PT T T++ TP +P + T +P + + P +P
Sbjct: 2166 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2225
Query: 1300 VPTPEVAAIPAASVPTPEVPAIPAAAVPPMEEVSPIGVPFLGVSAHTDSVPISEEGTPVL 1359
T P + P V P +P G + T + ++ TP
Sbjct: 2226 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTG 2283
Query: 1360 EEASST 1365
+ +T
Sbjct: 2284 TQTPTT 2289
Score = 90.5 bits (223), Expect = 1e-17
Identities = 110/570 (19%), Positives = 166/570 (29%), Gaps = 44/570 (7%)
Query: 834 PSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEE 893
P+ T + PT +P T+ P T + P P +
Sbjct: 1519 PTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTP 1578
Query: 894 EDVTAAAVSAPERATV---PAVTVSVPEGTAAV---AAVSSPEETAPAVAAAITQEGMSA 947
T S P T P T S P T SP T P T
Sbjct: 1579 SPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPT 1638
Query: 948 VAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAV 1007
P T T P P TT P T + ++T P+ P +
Sbjct: 1639 TTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTT--PSPPTTTM 1696
Query: 1008 PTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTS 1067
TP T+P++ + T P+S PPP T+P+ TP PT+ +P P +S
Sbjct: 1697 TTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTT-TPSPPTTTMTTLP-PTTTSS 1754
Query: 1068 PAAAVPTPEEPTSPAAAVPTPEEPTSPAAAV-----------PTPEEPTSPAAAVPTPEE 1116
P P P T P + + PT+P + P +P +
Sbjct: 1755 PLTTTPLPPSITPPTFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVCG 1814
Query: 1117 PASPA----AAVPTPEEPASP---------AAAVPTPEEPAFPAPAVPTP-----EESAS 1158
P A A P+ P + + E P +P E +
Sbjct: 1815 PGWAANISCRATMYPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQ 1874
Query: 1159 AAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVP--TPAAMVATLEEFT 1216
V P + PTP + PT P TP T+
Sbjct: 1875 CCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 1934
Query: 1217 SPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPT 1276
+P + + P + V+ PT T T++ TP +P + T
Sbjct: 1935 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 1994
Query: 1277 PEEPASPAAAVSNLEEP-ASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPMEEVSPI 1335
+P + + P +P T P + P V P +P
Sbjct: 1995 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPT 2052
Query: 1336 GVPFLGVSAHTDSVPISEEGTPVLEEASST 1365
G + T + ++ TP + +T
Sbjct: 2053 GTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2082
Score = 84.7 bits (208), Expect = 6e-16
Identities = 111/494 (22%), Positives = 155/494 (31%), Gaps = 71/494 (14%)
Query: 858 TSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVP 917
T++ P P GT P ++ T + P T P
Sbjct: 3952 TTVTPTPTPTGTQT-----PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 4006
Query: 918 EGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTP 977
GT ++P T V T G +P + T +T TP G TP
Sbjct: 4007 TGTQT--PTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTPTP-TPTGTQTP 4058
Query: 978 ATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPE-------EPTSPA 1030
TT P T V+ P TP T+ PTP P +
Sbjct: 4059 TTT------PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 4112
Query: 1031 AAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAA--------VPTPEEPTSPA 1082
V P PT TP T+ PTP +P PTP PT
Sbjct: 4113 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 4171
Query: 1083 AAVPTPEEPTSPAAAVPTP---------EEPTSPAAAVPT---PEEPASP----AAAVPT 1126
TP T+ PTP T+P A + T P E ++P + + P
Sbjct: 4172 TPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPL 4231
Query: 1127 PEEPASPAAAVPTPEEPAFPAPAVPT-PEESASAAVAVPTPEESASPAAAVPTPAESASF 1185
E + P E + P+ PT P ++ P P + SP + S
Sbjct: 4232 TESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSS 4291
Query: 1186 AAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSN-----PEE 1240
+A + + T+ +A PTP + T+ P+S L V N P E
Sbjct: 4292 SAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSV----LICCVLNDTYYAPGE 4347
Query: 1241 PTSPAAAVPTLEEPTSSAAAVL---------TPEELSSPAASVPTPEEPAS-PAAAVSNL 1290
T S + L TP +P+ S PTP +P+S P+
Sbjct: 4348 EVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGT 4407
Query: 1291 EEPASPAAAVPTPE 1304
+ P P P E
Sbjct: 4408 KPPECPDFDPPRQE 4421
Score = 56.6 bits (135), Expect = 2e-07
Identities = 69/348 (19%), Positives = 102/348 (29%), Gaps = 61/348 (17%)
Query: 852 PSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPA 911
P+P + P T V P + I + T T P
Sbjct: 4073 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4132
Query: 912 VTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTP 971
T + T +P T +T +P T PIT
Sbjct: 4133 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-------TPTGTQTPTTTPITTTTTVT 4185
Query: 972 EGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAA 1031
P T P TA + T P ++ T +SP E T+ +
Sbjct: 4186 PTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLT------ESTTLLS 4239
Query: 1032 AVPPPEEPTSPAAAVPTPEEPTSPAAA---VPTPEEPTSPAAAVPTPEEPTSPAAAVPTP 1088
+PP E TS A TP PT+ + P P TSP S +A P+
Sbjct: 4240 TLPPAIEMTSTAPP-STPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPST 4298
Query: 1089 EEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAV------------------------ 1124
+ T+ +A PTP ++P+ T P + +
Sbjct: 4299 VQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTC 4358
Query: 1125 -------------------PTPEEPASPAAAVPTPEEPAFPAPAVPTP 1153
TP +P+ + PTP +P+ P+ PTP
Sbjct: 4359 YFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPS-STPSKPTP 4405
Score = 31.2 bits (69), Expect = 7.5
Identities = 16/47 (34%), Positives = 23/47 (48%), Gaps = 1/47 (2%)
Query: 995 STPEEPASPAAAVPTPEEPTS-PAAAVPTPEEPTSPAAAVPPPEEPT 1040
STP +P+ + PTP +P+S P+ P + P P P E T
Sbjct: 4378 STPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECPDFDPPRQENET 4424
>gi|169205253 PREDICTED: hypothetical protein [Homo sapiens]
Length = 3859
Score = 136 bits (343), Expect = 1e-31
Identities = 138/562 (24%), Positives = 207/562 (36%), Gaps = 53/562 (9%)
Query: 828 IPVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVAS 887
+PV S V D + + P+ + +P +VP D V+
Sbjct: 979 VPVASADSPFVPVTPADDPIVSVTPAESPAIPVTQADSP--------VVPVTSADRPVSP 1030
Query: 888 IVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGM-- 945
+ + + V A P PA T P +A V +P V +
Sbjct: 1031 VTTADGRIVPVTAAGDPIVPVTPADTPGSPVTSADGPVVPVTSADSPFVPVTPPDGPVVP 1090
Query: 946 --SAVAGFSPEWAALAITVPITEEDG------TPEGPVTPATTVHAPEEPDTAAVRVSTP 997
SA +P +A VP+T DG + +GPV P T +P P T A P
Sbjct: 1091 VTSADGPVAPVSSADGPVVPVTSADGPVAPVSSADGPVVPVTPADSPFIPVTTADDPIVP 1150
Query: 998 EEPA-SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPA 1056
PA SP +V + P P TP + SP VPP P P ++ +P P PA
Sbjct: 1151 VTPADSPVLSVTLADSPVVPV----TPAD--SPVIPVPPANGPVVPVSSADSPFVPVIPA 1204
Query: 1057 AAVPTPEE-------PTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAA 1109
+ + P SP + P+ P +V + P P V + P P
Sbjct: 1205 DGLVVLDSSTDVLVVPVSPTDGILVPDLADDPVVSVTIADSPVIP---VTPADSPVVPVT 1261
Query: 1110 AVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEES 1169
+ +P P +PA + P P +V T + P V T + + +P
Sbjct: 1262 SADSPVVPVTPADSPVILVTPVGPVVSVTTADGPVV---LVSTADSPVIPVTSADSPVVP 1318
Query: 1170 ASPAAAVPTPAESASFAAV-VATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEP 1228
+PA P SA V V ++P P +P V E SPA V ++ P
Sbjct: 1319 VTPADGPVVPVTSADSPFVPVTPADDPIVPVTPADSPIVSVTPAE---SPAIPVTPADSP 1375
Query: 1229 ASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEEL-SSPAASVPTPEEPASPA--- 1284
+ +P P + A + PT +TP + SP S P P +PA
Sbjct: 1376 VVPVTSADSPLIPLTTAGSRVVPVTPTGDPIVPVTPADTPGSPVTSADGPVVPVTPAGDP 1435
Query: 1285 -AAVSNLEEPASPAAAVPTPEVAAI----PAASVPTPEVPAIP-AAAVPPMEEVSPIGVP 1338
V+ + P SP + P V P V P+ P +P +A P+ V+P P
Sbjct: 1436 IVPVTPADTPGSPVTSADGPVVPVTTPDGPLVPVSPPDGPVVPVTSADGPVVPVTPADSP 1495
Query: 1339 FLGVSAHTDS-VPISEEGTPVL 1359
F+ V+ D VP++ +PV+
Sbjct: 1496 FIPVTTADDPIVPVTPADSPVV 1517
Score = 134 bits (336), Expect = 8e-31
Identities = 154/590 (26%), Positives = 220/590 (37%), Gaps = 52/590 (8%)
Query: 801 DSDSFLNIFPEKQVTKA-GNTEPVLE-EWIPVLQRPSRTAAVPTVKDALDAALPSPEEGT 858
D+DS P VT A G PV + +PV P+ VP A S +G
Sbjct: 1722 DTDS-----PGSPVTSADGPVVPVTSADSLPVPVTPADGPVVPVTSADGPVAPVSSADGP 1776
Query: 859 SIAAVPAPEGTAVVAAL----VPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTV 914
+ PA V VP D V + V + +P +PA +
Sbjct: 1777 VVPVTPADSPVVPVTTADDPTVPVTPADSPVVPVPPANGPIVPVTSADSPFVPVIPADGL 1836
Query: 915 SVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDG----- 969
V + + V V V +S SP +P+T D
Sbjct: 1837 VVLDSSTDVLVVPVSPTDGILVPDLADDPVVSVTIADSP-------VIPVTPADSPVVLV 1889
Query: 970 TP-EGPVTPATTVHAPEEPDTAAVRVSTPEEPAS-PAAAVPTPEEPTSPAAAVPTPEEPT 1027
TP +GPV P T+V P P T A P P P V ++P P + +P
Sbjct: 1890 TPADGPVVPVTSVDNPVVPVTPADNPVIPVTPVDDPVVPVTPADDPIVPVTSADSPIVSV 1949
Query: 1028 SPAAA----VPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAA 1083
+PA + V P + P P A+ +P P +PA V P P P P +PA
Sbjct: 1950 TPADSPVFPVTPADSPVIPVASADSPLVPVTPADMVVVPVIPAD------GPVIPVTPAE 2003
Query: 1084 AVPTPEEPT-SPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEE 1142
+ P PT SP V + + P P A +P P +PA + P P TP +
Sbjct: 2004 SPAIPVTPTDSPVVPVTSADSPVIPVTA-DSPFVPVTPADSPVIPVTPPDDLVVPVTPID 2062
Query: 1143 -PAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVA-TLEEPTSPAA 1200
P P V P S + A + P A TPA+S A L P +PA
Sbjct: 2063 CPVVPVTLVDCPVVSVTPANSPVDPVTPADGPVVPVTPADSPVIPVTPADDLIVPVTPAD 2122
Query: 1201 SVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAA 1260
S ++ ++ SP V ++ P A+ +P P +PA V P
Sbjct: 2123 S------LIVSVTPADSPVVPVTPADSPVISVASADSPVVPVTPADTVVVPVTPADGPVI 2176
Query: 1261 VLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAA--VPTPEVAAIPAASVPTPEV 1318
+TP E SPA V + P P + P +PA + VP P A+ P V +
Sbjct: 2177 PVTPAE--SPAIPVTPADSPVVPVTPADDPVVPVTPADSPIVPVPP-ASDPVVPVTPADT 2233
Query: 1319 PAIP-AAAVPPMEEVSPIGVPFLGVS-AHTDSVPISEEGTPVLEEASSTG 1366
P P A+A P+ V+ P + V+ + VP++ +PV S+ G
Sbjct: 2234 PGSPVASADGPVVPVTSADSPLVPVTPGDSPVVPVTPADSPVFPVTSADG 2283
Score = 132 bits (333), Expect = 2e-30
Identities = 124/522 (23%), Positives = 200/522 (38%), Gaps = 51/522 (9%)
Query: 855 EEGTSIAAVP-APEGTAVVAALVPFPHEDILVAS--IVSLEEEDVTAAAVSAPERATVPA 911
+ T + VP +P +V L P + +A ++ + D T V+ + VP
Sbjct: 1559 DSSTDVLVVPVSPTDGVLVPDLADDPVVSVTIADSPVIPVTPADSTVVPVTLADGPVVPV 1618
Query: 912 VTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDG-- 969
+V +P V + P V + A P +A VP+T DG
Sbjct: 1619 TSVDIP--VVPVTPANGPVAPVTPVDDPVVSVN-PADGSVVPVTSADCPVVPVTPADGLV 1675
Query: 970 ---TP-EGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEE 1025
TP + P+ P T +P V V++ + P P +P P + A +
Sbjct: 1676 VPVTPADSPIVPVTPADSP------VVLVTSADSPVIPVTPADSPVVPVTSA----DTDS 1725
Query: 1026 PTSPAAAVPPPEEPTSPAAAVPTPEEPT-SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAA 1084
P SP + P P + A ++P P P P V + + P +P ++ P P +PA
Sbjct: 1726 PGSPVTSADGPVVPVTSADSLPVPVTPADGPVVPVTSADGPVAPVSSADGPVVPVTPA-- 1783
Query: 1085 VPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPA 1144
SP V T ++PT P TP + SP VP P P + +P P
Sbjct: 1784 -------DSPVVPVTTADDPTVPV----TPAD--SPVVPVPPANGPIVPVTSADSPFVPV 1830
Query: 1145 FPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFA-AVVATLEEPTSPAASVP 1203
PA + + S V +P + P S + A + V + SP V
Sbjct: 1831 IPADGLVVLDSSTDVLVVPVSPTDGILVPDLADDPVVSVTIADSPVIPVTPADSPVVLVT 1890
Query: 1204 TPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPA--AAVPTLEEPTSSAAAV 1261
V + +P V ++ P V +P P +PA VP TS+ + +
Sbjct: 1891 PADGPVVPVTSVDNPVVPVTPADNPVIPVTPVDDPVVPVTPADDPIVPV----TSADSPI 1946
Query: 1262 LTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAA----IPAASVPTPE 1317
++ SP V + P P A+ + P +PA V P + A IP +P
Sbjct: 1947 VSVTPADSPVFPVTPADSPVIPVASADSPLVPVTPADMVVVPVIPADGPVIPVTPAESPA 2006
Query: 1318 VPAIPAAAVPPMEEVSPIGVPFLGVSAHTDSVPISEEGTPVL 1359
+P P + P+ V+ P + V+A + VP++ +PV+
Sbjct: 2007 IPVTPTDS--PVVPVTSADSPVIPVTADSPFVPVTPADSPVI 2046
Score = 130 bits (328), Expect = 7e-30
Identities = 137/555 (24%), Positives = 199/555 (35%), Gaps = 66/555 (11%)
Query: 853 SPEEGTSIAAVPAPEGTAVVAA----LVPFPHEDILVASIVSLEEEDVTAAAVSAPERAT 908
+P +G + PA V +VP D L+ S+ + V +P +
Sbjct: 2089 TPADGPVVPVTPADSPVIPVTPADDLIVPVTPADSLIVSVTPADSPVVPVTPADSPVISV 2148
Query: 909 VPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEED 968
A + VP A V P + +T A+ P A + VP+T D
Sbjct: 2149 ASADSPVVPVTPADTVVVPVTPADGPVIP--VTPAESPAI----PVTPADSPVVPVTPAD 2202
Query: 969 GTPEGPVTPATTVHAPEEPDTAAVRVSTPEE-PASPAAAVPTPEEPTSPAAAVPTPEEP- 1026
P PVTPA + P P + V TP + P SP A+ P P + A + P P
Sbjct: 2203 D-PVVPVTPADSPIVPVPPASDPVVPVTPADTPGSPVASADGPVVPVTSADSPLVPVTPG 2261
Query: 1027 TSPAAAVPPPEEPTSPAAAVPTP-------EEPTSPAAAVPTPEEPTSPAAAVPTPEEPT 1079
SP V P + P P + P ++P P P P SPA + P P
Sbjct: 2262 DSPVVPVTPADSPVFPVTSADGPVFPVTLADDPVFPVTPADDPIFPVSPADSPVVPVTPA 2321
Query: 1080 S-PAAAVPTPEEPTSPAAAVPTPEEP--------------------TSPAAAVPTPEEPA 1118
+ P VP P + +P P SP +P P+
Sbjct: 2322 NIPVVPVPPANGSVVPVTSAGSPFVPIIPADGLVVLDSSTDVLVVLVSPTDGIPVPDLAD 2381
Query: 1119 SPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEES----ASPAA 1174
P +V T + P P +P P PA P S + V TP +S +PA
Sbjct: 2382 DPVVSVTTSDSPVIPVTPTDSPVVPVAPADGPVVPVTSVDSPVVPVTPADSPVIPVTPAD 2441
Query: 1175 AVPTPAESASFAAV-VATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAA 1233
++ PA A V V + P P + P V + + P P + A
Sbjct: 2442 SLVVPATPADDPVVSVTPADGPVVPVTTADIPVISVTSADSPVVPVTPADGLVVPVTSAD 2501
Query: 1234 AVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEP 1293
+V P P + VP +P S + TP + +P SV + + P P + P
Sbjct: 2502 SVVVPATP-ADCPLVPV--DPADSPIVLFTPYD--NPVVSVTSDDSPVFPVTPADSSVVP 2556
Query: 1294 ASPAAAVPTPEVAAIPAASVPTPEVPAIPA--------AAVPPMEEVSPIGVPFLGVSAH 1345
+PA V +P P VP PA +A P+ V+P P VS
Sbjct: 2557 VTPAG------VPVVPVTPGDGPVVPVTPADSLVVPVTSADSPVFPVTPADSPVFPVSPA 2610
Query: 1346 TD-SVPISEEGTPVL 1359
D VP++ +PV+
Sbjct: 2611 DDLVVPVTPGDSPVV 2625
Score = 127 bits (318), Expect = 1e-28
Identities = 152/620 (24%), Positives = 227/620 (36%), Gaps = 63/620 (10%)
Query: 774 PDG--VETVNDTKPELNVASSEGGEMERRDSDSFLNIFPEKQVTKAGNT-EPVLEEWIPV 830
PDG V + P V+S++G + +DS P VT A + PV PV
Sbjct: 483 PDGPVVPVTSADGPVAPVSSADGPVVPVTPADS-----PFIPVTTADDLIVPVTPADSPV 537
Query: 831 LQ-RPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVV----AALVPFPHEDILV 885
L P+ + A+P +P G + A V +VP D V
Sbjct: 538 LSVTPAESPAIPVTPADSPIVPVTPANGPVVPVTSADSPFVPVIPADGPVVPVTPADSPV 597
Query: 886 ASIVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGM 945
+ + ++ +P PA + VP A V +P V + +
Sbjct: 598 VPVTPADSPVLSVTLADSPAVPVTPADSPVVPVTPADGPVVPVASADSPFVPVTPADDPI 657
Query: 946 SAVAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAA----VRVSTPEEPA 1001
+V A + +P+T+ D PV P T+ P P T A V V+ +P
Sbjct: 658 VSVT------PAESPAIPVTQADS----PVVPVTSADRPVIPVTTADGRIVPVTAAGDPI 707
Query: 1002 SPAAAVPTPEEPTSPAAAVPTP-EEPTSPAAAVPPPEEPTSPAAAVPTPEEPTS----PA 1056
P TP P + A P SP V PP+ P P + P P S P
Sbjct: 708 VPVTPADTPGSPVTSADGPVVPVTSADSPFVPVTPPDGPVVPVTSADGPVAPVSSADGPV 767
Query: 1057 AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE 1116
V + + P +P ++ P P +PA + PA V + + P P +P
Sbjct: 768 VPVTSADGPVAPVSSADGPVVPVTPA-------DTNGPAVPVTSADSPFVPVIPADSPVV 820
Query: 1117 PASPAAAVPTPEEPAS----PAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASP 1172
P +PA P PA P + +P P PA P +S++ + VP P
Sbjct: 821 PVTPADDPIVPVTPADSSFVPVISADSPFVPVIPADG-PVVVDSSTDVLVVP-----VFP 874
Query: 1173 AAAVPTPAESASFA-AVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASL 1231
+ PA FA V L SP V P +V + P A V +++ P
Sbjct: 875 VNCILVPA----FADETVVPLNPADSPVIPVTPPDDLVVPVTPTDCPVAPVTSADCPVVP 930
Query: 1232 AAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLE 1291
+P +P + A P +TP + SP SV + P P A+ +
Sbjct: 931 VTPADSPADPVTAADGPVVPFTPADDPIVPVTPAD--SPVVSVTPADGPVVPVASADSPF 988
Query: 1292 EPASPA----AAVPTPEVAAIPAASVPTPEVPAIPAAAVPPMEEVSPIGVPFLGVSAHTD 1347
P +PA +V E AIP +P VP +A P+ V+ + V+A D
Sbjct: 989 VPVTPADDPIVSVTPAESPAIPVTQADSPVVPV--TSADRPVSPVTTADGRIVPVTAAGD 1046
Query: 1348 S-VPISEEGTPVLEEASSTG 1366
VP++ TP S+ G
Sbjct: 1047 PIVPVTPADTPGSPVTSADG 1066
Score = 125 bits (313), Expect = 4e-28
Identities = 166/703 (23%), Positives = 259/703 (36%), Gaps = 120/703 (17%)
Query: 765 LLVEELRLNPDGVETVNDTKPELNVASSEGGEMERRDSDSFLNIFPEKQVTKAGNTEPVL 824
+LV +L +P T+ D+ P + V ++ + +DS P VT A + ++
Sbjct: 1227 ILVPDLADDPVVSVTIADS-PVIPVTPADSPVVPVTSADS-----PVVPVTPADSPVILV 1280
Query: 825 EEWIPVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEG-----TAVVAALVPFP 879
PV+ + V V A +P + + V +G T+ + VP
Sbjct: 1281 TPVGPVVSVTTADGPVVLVSTADSPVIPVTSADSPVVPVTPADGPVVPVTSADSPFVPVT 1340
Query: 880 HEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAA 939
D + + + V+ +P PA + VP +A + P TA +
Sbjct: 1341 PADDPIVPVTPADSPIVSVTPAESPAIPVTPADSPVVPVTSADSPLI--PLTTAGSRVVP 1398
Query: 940 ITQEGMSAV------AGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAP--------- 984
+T G V SP +A VP+T G P PVTPA T +P
Sbjct: 1399 VTPTGDPIVPVTPADTPGSPVTSADGPVVPVTPA-GDPIVPVTPADTPGSPVTSADGPVV 1457
Query: 985 --EEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAA----VPTPEEPTSPAAAVPPPEE 1038
PD V VS P+ P P + P P +PA + V T ++P P V P +
Sbjct: 1458 PVTTPDGPLVPVSPPDGPVVPVTSADGPVVPVTPADSPFIPVTTADDPIVP---VTPADS 1514
Query: 1039 PTSPAAAVPTPEEPTSPA-------AAVPTPEEPTSPAAAVPTPEE-------PTSPAAA 1084
P P P P +PA + P P PA + + P SP
Sbjct: 1515 PVVPVTPADIPVVPVTPANGPVIHVTSADCPFVPVIPADGLVALDSSTDVLVVPVSPTDG 1574
Query: 1085 VPTPEEPTSPAAAVP---TPEEPTSPAAAVPTP----EEPASPAAAVPTPEEPASPA--- 1134
V P+ P +V +P P +PA + P + P P +V P P +PA
Sbjct: 1575 VLVPDLADDPVVSVTIADSPVIPVTPADSTVVPVTLADGPVVPVTSVDIPVVPVTPANGP 1634
Query: 1135 -------------------AAVPT-----PEEPAFPAPAVPTPEESASAAVAVPTPEES- 1169
+ VP P P PA + P A + + TP +S
Sbjct: 1635 VAPVTPVDDPVVSVNPADGSVVPVTSADCPVVPVTPADGLVVPVTPADSPIVPVTPADSP 1694
Query: 1170 -----ASPAAAVP-TPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEF-------T 1216
++ + +P TPA+S A + P SP S P V + +
Sbjct: 1695 VVLVTSADSPVIPVTPADSPVVPVTSADTDSPGSPVTSADGPVVPVTSADSLPVPVTPAD 1754
Query: 1217 SPAASVPTSEEPASLAAAVSNPEEPTSPA----AAVPTLEEPT---SSAAAVLTPEELSS 1269
P V +++ P + ++ P P +PA V T ++PT + A + + P ++
Sbjct: 1755 GPVVPVTSADGPVAPVSSADGPVVPVTPADSPVVPVTTADDPTVPVTPADSPVVPVPPAN 1814
Query: 1270 ----PAASVPTPEEPASPAAAVSNLEE-------PASPAAAVPTPEVAAIPAASVPTPEV 1318
P S +P P PA + L+ P SP + P++A P SV +
Sbjct: 1815 GPIVPVTSADSPFVPVIPADGLVVLDSSTDVLVVPVSPTDGILVPDLADDPVVSVTIADS 1874
Query: 1319 PAIPAA-AVPPMEEVSPIGVPFLGV-SAHTDSVPISEEGTPVL 1359
P IP A P+ V+P P + V S VP++ PV+
Sbjct: 1875 PVIPVTPADSPVVLVTPADGPVVPVTSVDNPVVPVTPADNPVI 1917
Score = 121 bits (304), Expect = 4e-27
Identities = 152/610 (24%), Positives = 223/610 (36%), Gaps = 89/610 (14%)
Query: 785 PELNVASSEGGEMERRDSDSFLNIFPEKQVTKAGN----TEPVLEEWIPVLQRPSRTAAV 840
P VAS++G + +DS +FP VT A + P PV P+ +AA+
Sbjct: 147 PVFPVASADGPVVPVTPADS--PVFP---VTPADSPLFPVTPADSPLFPVT--PADSAAI 199
Query: 841 PTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAA----LVPFPHEDILVASIVSLEEEDV 896
P +P GT + PA VA+ +VP D + + + V
Sbjct: 200 PVTPADGPVVHVTPANGTVVPVTPADSPVVTVASTDSPVVPVTPADDPIVPVTPADSSFV 259
Query: 897 TAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPE-- 954
+ +P +PA +G V + + + + V F+ E
Sbjct: 260 PVISADSPFVPVIPA------DGPVVV------DSSTDVLVVPVFPVNCILVPAFADETI 307
Query: 955 ---WAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPE 1011
++ V +T D P PVTPA D+ + V+ + P P +P
Sbjct: 308 XXXXXXXSLVVSVTTADD-PIVPVTPA---------DSPVLSVTLADSPVVPVTPADSPF 357
Query: 1012 EPTSPAAAVPTPEEPT-SPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPT-SPA 1069
P PA P P SP V P + P A+ +P P +PA P SP
Sbjct: 358 VPAIPADGPVVPVTPADSPVVPVTPADGPVVSVASADSPFVPVTPADDPIVSVTPADSPV 417
Query: 1070 AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEE 1129
V + + P P V T + P A P P +PA + P SP V + +
Sbjct: 418 VPVTSADSPLIP---VTTADGRVVPVTAAGDPIVPVTPA------DTPGSP---VTSADG 465
Query: 1130 PASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVV 1189
P P + P P P P SA VA P SA TPA+S
Sbjct: 466 PVVPVTSADIPLVPVTPPDGPVVPVTSADGPVA---PVSSADGPVVPVTPADS------- 515
Query: 1190 ATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPA---- 1245
P V T ++ + SP SV +E PA +P P +PA
Sbjct: 516 --------PFIPVTTADDLIVPVTPADSPVLSVTPAESPAIPVTPADSPIVPVTPANGPV 567
Query: 1246 AAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPA-SPAAAVSNLEEPASPAAAVPTPE 1304
V + + P P +PA S P PA SP +V+ + PA P +P
Sbjct: 568 VPVTSADSPFVPVIPADGPVVPVTPADSPVVPVTPADSPVLSVTLADSPAVPVTPADSPV 627
Query: 1305 V-------AAIPAASVPTPEVPAIPAAAVPPMEEVSPIGVPFLGVS-AHTDSVPISEEGT 1356
V +P AS +P VP PA P+ V+P P + V+ A + VP++
Sbjct: 628 VPVTPADGPVVPVASADSPFVPVTPAD--DPIVSVTPAESPAIPVTQADSPVVPVTSADR 685
Query: 1357 PVLEEASSTG 1366
PV+ ++ G
Sbjct: 686 PVIPVTTADG 695
Score = 120 bits (301), Expect = 9e-27
Identities = 140/566 (24%), Positives = 210/566 (37%), Gaps = 83/566 (14%)
Query: 829 PVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASI 888
PV R V D + P+ G+ + + P V +A PF +
Sbjct: 1030 PVTTADGRIVPVTAAGDPIVPVTPADTPGSPVTSADGPV-VPVTSADSPFVPVTPPDGPV 1088
Query: 889 VSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAA------ITQ 942
V + D A VS+ + VP + P VA VSS + V A +T
Sbjct: 1089 VPVTSADGPVAPVSSADGPVVPVTSADGP-----VAPVSSADGPVVPVTPADSPFIPVTT 1143
Query: 943 EGMSAVAGFSPEWAALAIT------VPITEEDGT------PEGPVTPATTVHAPEEP--- 987
V + L++T VP+T D GPV P ++ +P P
Sbjct: 1144 ADDPIVPVTPADSPVLSVTLADSPVVPVTPADSPVIPVPPANGPVVPVSSADSPFVPVIP 1203
Query: 988 -DTAAVRVSTPEE---PASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPA 1043
D V S+ + P SP + P+ P +V + P P V P + P P
Sbjct: 1204 ADGLVVLDSSTDVLVVPVSPTDGILVPDLADDPVVSVTIADSPVIP---VTPADSPVVPV 1260
Query: 1044 AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE 1103
+ +P P +PA + P P +V T + P V T + P P + +P
Sbjct: 1261 TSADSPVVPVTPADSPVILVTPVGPVVSVTTAD---GPVVLVSTADSPVIPVTSADSPVV 1317
Query: 1104 PTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAV 1163
P +PA + P P + +P P +PA ++P P TP +S +V
Sbjct: 1318 PVTPA------DGPVVPVTSADSPFVPVTPA------DDPIVPV----TPADSPIVSV-- 1359
Query: 1164 PTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVP 1223
TP E SPA V TPA+S V + SP + T + V + P V
Sbjct: 1360 -TPAE--SPAIPV-TPADSP-----VVPVTSADSPLIPLTTAGSRVVPVTPTGDPIVPVT 1410
Query: 1224 TSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASP 1283
++ P S + P P +PA P + + +T + P V TP+ P P
Sbjct: 1411 PADTPGSPVTSADGPVVPVTPAGDPIVPVTPADTPGSPVTSAD--GPVVPVTTPDGPLVP 1468
Query: 1284 AAAVSNLEEPASPAAAVPTPEVAAIPAAS----VPTPEVPAIPAA-AVPPMEEVSPIGVP 1338
VS + P P + P V PA S V T + P +P A P+ V+P +P
Sbjct: 1469 ---VSPPDGPVVPVTSADGPVVPVTPADSPFIPVTTADDPIVPVTPADSPVVPVTPADIP 1525
Query: 1339 FLGVSAHTDSVPISEEGTPVLEEASS 1364
VP++ PV+ S+
Sbjct: 1526 V---------VPVTPANGPVIHVTSA 1542
Score = 107 bits (266), Expect = 1e-22
Identities = 129/543 (23%), Positives = 198/543 (36%), Gaps = 88/543 (16%)
Query: 899 AAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAAL 958
A V+ + +P+ V++ G+ V ++ +T +V +T+ G V + +
Sbjct: 2 APVATEIKKYLPSGAVTLLPGSPVVLPITVVVQTDGSVVP-VTRAGSPFVPVIPADGLVV 60
Query: 959 ------AITVPITEEDG--------TPEGPVTPATTVHAPEEP-DTAAVRVSTPEEPASP 1003
+ VP+ DG P PVTPA + P P D+ + V++ ++P P
Sbjct: 61 LDSSTDVLVVPVFPADGILVPDFADNPVVPVTPADDLVFPVTPADSPVIPVTSADDPVVP 120
Query: 1004 AAAVPTPEEPTS----PAAAVPTPEEPTSPAAA-------VPPPEEPTSPAAAVPTPEEP 1052
P P + P V + P P A+ V P + P P +P P
Sbjct: 121 ITPADNPVVPVTSANGPVIPVTPADSPVFPVASADGPVVPVTPADSPVFPVTPADSPLFP 180
Query: 1053 TSPAAAVPTPEEPTSPAAAVPTPEE----PTSPAAAVPTPEEPT-SPAAAVPTPEEPTSP 1107
+PA + P P AA TP + +PA P P SP V + + P P
Sbjct: 181 VTPADSPLFPVTPADSAAIPVTPADGPVVHVTPANGTVVPVTPADSPVVTVASTDSPVVP 240
Query: 1108 AAAVPTPEEPASPA--AAVP--------TPEEPASPAAAVPTPEE----PAFPAPAVPTP 1153
P P +PA + VP P PA V + + P FP + P
Sbjct: 241 VTPADDPIVPVTPADSSFVPVISADSPFVPVIPADGPVVVDSSTDVLVVPVFPVNCILVP 300
Query: 1154 ----------EESASAAVAVPTPEESASPAAAVPTPAESASFA----AVVATLEEPTSPA 1199
S V+V T ++ P +P S + A V + P PA
Sbjct: 301 AFADETIXXXXXXXSLVVSVTTADDPIVPVTPADSPVLSVTLADSPVVPVTPADSPFVPA 360
Query: 1200 ASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAA 1259
P V + SP V ++ P A+ +P P +PA P S
Sbjct: 361 IPADGPVVPVTPAD---SPVVPVTPADGPVVSVASADSPFVPVTPADDPIVSVTPADSPV 417
Query: 1260 AVLTPEELSSPAASVPTPEEPASPAAA-------VSNLEEPASPAAAVPTPEV----AAI 1308
+T + SP V T + P A V+ + P SP + P V A I
Sbjct: 418 VPVTSAD--SPLIPVTTADGRVVPVTAAGDPIVPVTPADTPGSPVTSADGPVVPVTSADI 475
Query: 1309 PAASVPTPEVPAIP-----------AAAVPPMEEVSPIGVPFLGVSAHTD-SVPISEEGT 1356
P V P+ P +P ++A P+ V+P PF+ V+ D VP++ +
Sbjct: 476 PLVPVTPPDGPVVPVTSADGPVAPVSSADGPVVPVTPADSPFIPVTTADDLIVPVTPADS 535
Query: 1357 PVL 1359
PVL
Sbjct: 536 PVL 538
Score = 82.0 bits (201), Expect = 4e-15
Identities = 155/651 (23%), Positives = 226/651 (34%), Gaps = 126/651 (19%)
Query: 810 PEKQVTKA-GNTEPVLEEWIPVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEG 868
P VT A G PV IPV+ S + V V A +P TS +V P
Sbjct: 2453 PVVSVTPADGPVVPVTTADIPVISVTSADSPVVPVTPADGLVVPV----TSADSVVVP-A 2507
Query: 869 TAVVAALVPFPHEDILVA-------SIVSLEEEDVTAAAVSAPERATVPAVTVSVP---- 917
T LVP D + +VS+ +D V+ + + VP VP
Sbjct: 2508 TPADCPLVPVDPADSPIVLFTPYDNPVVSVTSDDSPVFPVTPADSSVVPVTPAGVPVVPV 2567
Query: 918 -EGTAAVAAVSSPEETAPAVAAAITQ-----EGMSAVAGFSPEWAALAITVPITEEDG-- 969
G V V+ + V +A + S V SP A + VP+T D
Sbjct: 2568 TPGDGPVVPVTPADSLVVPVTSADSPVFPVTPADSPVFPVSP---ADDLVVPVTPGDSPV 2624
Query: 970 -------------TP-EGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEE--- 1012
TP +GPV P T + P P T+A P PA + + +
Sbjct: 2625 VPVSPADSPVVLVTPADGPVVPVTPANGPVVPVTSADSPFVPVIPADGLVVLDSSTDVLV 2684
Query: 1013 -PTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAA 1071
P P + P+ P V P ++P P P P +PA P P +PA
Sbjct: 2685 VPVFPTDGILVPDLADDPVVPVTPGDDPVVPVTPGDDPVIPVTPAD--DGPFVPVTPAVG 2742
Query: 1072 VPTPEEPTSPAAAVP---------------------TPEEPTSPAAAVPTPEEP--TSPA 1108
P + T+ + VP T + P +V P T A
Sbjct: 2743 -PVVPDLTADDSVVPDSLTDDPVISVCPDDGLVVPDTVRDSDGPEVSVYPVTGPVVTDSA 2801
Query: 1109 AAVPTPEEPAS-------PAAAVPTPEEPASPAAAVPTP--EEPAFPAPAVPTPEESASA 1159
A P P + P VP + + VP P + P F P+V P ++
Sbjct: 2802 ADCPVVSVPLTDGLVVLCPPDEVPAVHDSVTNGLVVPDPVIDGPVFSNPSVDGPIVPVAS 2861
Query: 1160 AVAVPTPEESASPAAAVPTPAESASFAAVVAT-----LEEPTSPA--ASVPTPAAMVATL 1212
A P+ P A P + ++F+ VV + ++ +PA A VP +
Sbjct: 2862 ADNPGVPD----PIRAFPVVPKPSTFSPVVTSTPADWIDVIVTPADCADVPVNPVNGPVV 2917
Query: 1213 EEFTS--PAASVPTSEE------PASLAAAVSNP--EEPTSPAAAVPTLEEPTSSAAAVL 1262
+ + P VP +++ P + A VS P + P A L P + A +
Sbjct: 2918 PDLSGDCPVVPVPPTDDIVVLNPPDVVFAVVSTPVTDGPVVTDPATDGLMVPVTPANGSV 2977
Query: 1263 TPEELS---------------SPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVA- 1306
P LS SP P +P++ ++ VSN P + VP P +A
Sbjct: 2978 APVTLSEYPDVTVTPADGTVVSPTIGGPVVPDPSADSSVVSN---PTTDGLIVPNPLLAG 3034
Query: 1307 -AIPAASVPTPEVPAIPAAAVPPMEEVSPIGVPFLGVSAHTDSVPISEEGT 1356
+P P P I A P V+P P V A T P+ + T
Sbjct: 3035 PVVPVTPTDGPLAPVILADC--PDVTVTPADGPV--VCAFTTGGPVFPDPT 3081
Score = 74.3 bits (181), Expect = 8e-13
Identities = 126/561 (22%), Positives = 185/561 (32%), Gaps = 90/561 (16%)
Query: 829 PVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVA-- 886
PV P+ V + D + +P ++A PA V +P D+LV
Sbjct: 3075 PVFPDPTAEGLVVSNPTVDDPVVTNPSTKGLVSATPADCADVPV---IPADCPDVLVNLV 3131
Query: 887 --SIVSLEEEDVTAAAVSAPERAT-------VPAVTVSVPEGTAAVAAVSSPEETAPAVA 937
S+V D T +VS P+ VP V V + +G P+ T +
Sbjct: 3132 NDSVVPDFTADWTVVSVSPPDDLVAPDPPDEVPVVLVPITDGPVV------PDLTTDGLV 3185
Query: 938 AAITQEGMSAVAGFSPEWAALAIT------VPITEEDGTPEG---------PVTPATTVH 982
++T G V F + + +T VP DG PVTPA
Sbjct: 3186 VSVTPAGAPVVPVFLTDCPDVTVTPADSPVVPDPSSDGPVVADSLDDDGLVPVTPADDSV 3245
Query: 983 APEEPDTAAVRVS-TPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTS 1041
P+ P V T + P +P +V P P +PA A PT S A P T
Sbjct: 3246 VPDSPANGLVVPDPTTDGPVAPDPSVDGPVVPVTPADA-PT----VSVTLADCPDVTVTP 3300
Query: 1042 PAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTP 1101
P V + + P + +P A + +PA P P + P
Sbjct: 3301 PDGLVVSDSKRGGPVVTGLSTNDPVITATPADFSDVTVTPADFEDVPVTPANCPDVPVNP 3360
Query: 1102 EEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAV 1161
E P AV P P+ + E P VP +P V P + +AA
Sbjct: 3361 ESPVVSDLAVDFLVVPVVPSDDLVVLEPPDK----VPVVPDPISNGLVVSDPITNNTAAT 3416
Query: 1162 AVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAAS 1221
P+ + S P V+ + P +P P + ++ +
Sbjct: 3417 D-PSVDGSVVP----------------VSPADGPVAPVTLADCPDVTITPADDSVVSDSK 3459
Query: 1222 VPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPA 1281
+ E + A P P +P + P S AV P +P P++
Sbjct: 3460 IRAEFEDVPVTIA-DCPNVPVNPKSG------PVVSDLAV------DCPVVPIPPPDDLV 3506
Query: 1282 SPAAAVSNLEEPASPAAAVPTP----EVAAIPAASVPTPEVPAIPAAAVPPMEEVSPIGV 1337
+P EP VP P V + P P P+I VP VSP G+
Sbjct: 3507 AP--------EPPDEVPVVPDPITDSLVVSDPMTDGPVASDPSIDGIVVP---VVSPSGL 3555
Query: 1338 PFLGVSAHTDSVPISEEGTPV 1358
L A +P + PV
Sbjct: 3556 LVLDSVADVSILPDTSADVPV 3576
Score = 66.2 bits (160), Expect = 2e-10
Identities = 141/638 (22%), Positives = 214/638 (33%), Gaps = 97/638 (15%)
Query: 785 PELNVASSEGGEMERRDSDS-FLNIFPEKQVTKAGNTEPVLEEWIPVLQRPSRTAAVPTV 843
P + V + G + +DS F+ + P + ++ VL +PV P+ VP +
Sbjct: 2643 PVVPVTPANGPVVPVTSADSPFVPVIPADGLVVLDSSTDVLV--VPVF--PTDGILVPDL 2698
Query: 844 KDALDAALP-SPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEEEDVTAAAVS 902
D D +P +P + + P + V P + V V D+TA
Sbjct: 2699 AD--DPVVPVTPGDDPVVPVTPGDDPVIPVTPADDGPF--VPVTPAVGPVVPDLTADDSV 2754
Query: 903 APERATV-PAVTVSVPEGTAAVAAV---SSPEETA-PAVAAAITQEGMSAVAGFSPEWAA 957
P+ T P ++V +G V PE + P +T P
Sbjct: 2755 VPDSLTDDPVISVCPDDGLVVPDTVRDSDGPEVSVYPVTGPVVTDSAADCPVVSVPLTDG 2814
Query: 958 LAITVPITE----EDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEP 1013
L + P E D G V P + P + + + P P A+ P P
Sbjct: 2815 LVVLCPPDEVPAVHDSVTNGLVVPDPVIDGPVFSNPSV------DGPIVPVASADNPGVP 2868
Query: 1014 TSPAAAVPTPEEPT--SPAAAVPPPE---EPTSPAAAVPTPEEPTSPAAAVPTPEEPTSP 1068
P A P +P+ SP P + +PA P P + P + +
Sbjct: 2869 -DPIRAFPVVPKPSTFSPVVTSTPADWIDVIVTPADCADVPVNPVNG----PVVPDLSGD 2923
Query: 1069 AAAVPTPEEPTSPAAAVPTPEEP----TSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAV 1124
VP P PT + P+ ++P P +P + VP PA+ + A
Sbjct: 2924 CPVVPVP--PTDDIVVLNPPDVVFAVVSTPVTDGPVVTDPATDGLMVPVT--PANGSVAP 2979
Query: 1125 PTPEE-------PASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVP 1177
T E PA PT P P P+ + S+ V+ PT + VP
Sbjct: 2980 VTLSEYPDVTVTPADGTVVSPTIGGPVVPDPS------ADSSVVSNPTTD-----GLIVP 3028
Query: 1178 TPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSN 1237
P L P P P A V + P +V ++ P A
Sbjct: 3029 NP-----------LLAGPVVPVTPTDGPLAPVILAD---CPDVTVTPADGPVVCAFTTGG 3074
Query: 1238 PEEPTSPAAAVPTLEEPTSSAAAVLTPEE----LSSPAASVPTPEEPAS-PAAAVSNLEE 1292
P P P A + PT V P ++PA P PA P V+ + +
Sbjct: 3075 PVFP-DPTAEGLVVSNPTVDDPVVTNPSTKGLVSATPADCADVPVIPADCPDVLVNLVND 3133
Query: 1293 PASP---------AAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPME------EVSPIGV 1337
P + + P VA P VP VP VP + V+P G
Sbjct: 3134 SVVPDFTADWTVVSVSPPDDLVAPDPPDEVPVVLVPITDGPVVPDLTTDGLVVSVTPAGA 3193
Query: 1338 PFLGV-SAHTDSVPISEEGTPVLEEASSTGMWIKEDLD 1374
P + V V ++ +PV+ + SS G + + LD
Sbjct: 3194 PVVPVFLTDCPDVTVTPADSPVVPDPSSDGPVVADSLD 3231
Score = 65.9 bits (159), Expect = 3e-10
Identities = 99/449 (22%), Positives = 150/449 (33%), Gaps = 74/449 (16%)
Query: 876 VPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEET-AP 934
VP + I +VS + TAA + + + VP P A V P+ T P
Sbjct: 3392 VPVVPDPISNGLVVSDPITNNTAATDPSVDGSVVPVSPADGP--VAPVTLADCPDVTITP 3449
Query: 935 AVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGT---------PEGPVTPATTVHAPE 985
A + ++ + A P A VP+ + G P P+ P + APE
Sbjct: 3450 ADDSVVSDSKIRAEFEDVPVTIADCPNVPVNPKSGPVVSDLAVDCPVVPIPPPDDLVAPE 3509
Query: 986 EPDTAAV---RVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAA----------A 1032
PD V ++ + P P +P+ VP SP+ +
Sbjct: 3510 PPDEVPVVPDPITDSLVVSDPMTDGPVASDPSIDGIVVPV----VSPSGLLVLDSVADVS 3565
Query: 1033 VPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPA------------AAVPTPEEPTS 1080
+ P P V + P +A P P P VP P +
Sbjct: 3566 ILPDTSADVPVTPVTLADGSVVPDSAPDCPVVPVLPTDGFVVLDLLVDGVVVPNPAD-VG 3624
Query: 1081 PAAAVPTPEEPTS----PAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAA 1136
P PT + P S P P P+ P P P S A V P P + A
Sbjct: 3625 PVVPDPTTDGPDSIKDFPLVPDPWPDCPVVPVTRTDGPVVLDSSADGVVVPVTPGDDSVA 3684
Query: 1137 VPTPEE-----------PAFPAPAVPTPEESASAA--VAVPTP--EESASPAAAVPTPAE 1181
+ TP + P P P+ P S A + VP P +++ P + P
Sbjct: 3685 LVTPTDNLVVPDLTTDGPVVPDPSADGPVVLVSLADDLLVPNPPVKDTVVPNSVADNPVA 3744
Query: 1182 SASFAAVVATLEEPTSPAASVPTPAA--MVATLEEFTSPAASVPTSEEPASLAAAVSNPE 1239
+P + VP P+A +V T P P++++P L +
Sbjct: 3745 L-----------DPVTDCPLVPEPSANGLVVTDSLDEGPVVPDPSADDPVVLNPETNGLV 3793
Query: 1240 EPTSPAAAVPTLEEPTSSAAAVLTPEELS 1268
P A + PT + A +TP++ S
Sbjct: 3794 VPDISANGPVVPDTPTDGSDATVTPDDCS 3822
Score = 51.2 bits (121), Expect = 7e-06
Identities = 76/359 (21%), Positives = 120/359 (33%), Gaps = 31/359 (8%)
Query: 828 IPVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVV-----AALVPFPHED 882
+PV+ P + V + P + V +P G V+ +++P D
Sbjct: 3514 VPVVPDPITDSLVVSDPMTDGPVASDPSIDGIVVPVVSPSGLLVLDSVADVSILPDTSAD 3573
Query: 883 ILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQ 942
+ V + + V +A P +P V + V +P + P V T
Sbjct: 3574 VPVTPVTLADGSVVPDSAPDCPVVPVLPTDGFVVLDLLVDGVVVPNPADVGPVVPDPTT- 3632
Query: 943 EGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPAS 1002
+G ++ F VP D P+ PV P T P D++A V P P
Sbjct: 3633 DGPDSIKDFP--------LVP----DPWPDCPVVPVTRTDGPVVLDSSADGVVVPVTPGD 3680
Query: 1003 PAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTP 1062
+ A+ TP + VP + T+ VP P P V ++ P V
Sbjct: 3681 DSVALVTPTD----NLVVP---DLTTDGPVVPDP-SADGPVVLVSLADDLLVPNPPVKDT 3732
Query: 1063 EEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAA 1122
P S A P +P + VP P S V T P P+ ++P
Sbjct: 3733 VVPNS-VADNPVALDPVTDCPLVPEP----SANGLVVTDSLDEGPVVPDPSADDPVVLNP 3787
Query: 1123 AVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAE 1181
P A P+ P + A TP++ + V + S VP ++
Sbjct: 3788 ETNGLVVPDISANGPVVPDTPTDGSDATVTPDDCSEVFVTATDGPDVVSDCPIVPETSD 3846
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 132 bits (333), Expect = 2e-30
Identities = 151/557 (27%), Positives = 222/557 (39%), Gaps = 90/557 (16%)
Query: 806 LNIFPEKQVTKAGNTEPVLEEWIPVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPA 865
L P T P + P +Q P +P ++ + +L SP S+ A P+
Sbjct: 354 LQTLPSPPATPPSQAPPSMTT--PPMQAPPSLQTIPPIQ--VPHSLTSP----SLQAPPS 405
Query: 866 PEGTAVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPER-ATVPAVTVSVPEGTAAVA 924
P + + A + T A++++P R A+ P + + + A
Sbjct: 406 PLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPA 465
Query: 925 AVSSPEETAPAVAAAITQ------EGMSAVAGFSPEWAALAITVPITEEDGT--PEGPVT 976
+ +PAV+ + + +S++A SP+ ++ +P E + P T
Sbjct: 466 SPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQT 525
Query: 977 PATTVH----------APEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEP 1026
P ++ AP TA+ ++TP P A + P SP P PE P
Sbjct: 526 PPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTT-PPPETP 584
Query: 1027 TSPAAAVPPPEEPTSPAAAVPT----PEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPA 1082
+S A PPP+ P PA A P P P SP A P P+ P P A+P + P SP
Sbjct: 585 SS--IATPPPQAP--PALASPPLQGLPSPPLSPLAT-PPPQAP--PXLALPPLQAPPSPP 637
Query: 1083 AAVP-----TPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAV 1137
A+ P TP A AV + P SP + P + P SP A+ P SP+A
Sbjct: 638 ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPV-QAPFSPPAS-----PPVSPSATP 691
Query: 1138 PTPEEPAFPAPAV---PTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEE 1194
P+ P+ AP + P+P S + + P ++ P AA P L+
Sbjct: 692 PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP--------------LQV 737
Query: 1195 PTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEP 1254
P SP AS P SP+A+ P P A + P P + P + P
Sbjct: 738 PPSPPASPPM------------SPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPP 785
Query: 1255 TSSAAAVLTP--EELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVP--TPEVAAIPA 1310
+ A+ TP + L SP AS P + P SP+A++ P SP A P P V A P
Sbjct: 786 PQAPPALATPPLQALPSPPASFP-GQAPFSPSASL-----PMSPLATPPPQAPPVLAAPL 839
Query: 1311 ASVPTPEVPAIPAAAVP 1327
VP P PA P P
Sbjct: 840 LQVP-PSPPASPTLQAP 855
Score = 132 bits (332), Expect = 2e-30
Identities = 154/568 (27%), Positives = 227/568 (39%), Gaps = 71/568 (12%)
Query: 834 PSRTAAVPTVKDALDAALPSPE-EGTSIAAVPAPEGTAV-----------VAALVPF-PH 880
P R A P + + L +P GT VP P+ A +A +P P
Sbjct: 287 PPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPP 346
Query: 881 EDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEE-TAPAVAAA 939
S+ +L T + + P T P + P + + P T+P++ A
Sbjct: 347 SPSAPPSLQTLPSPPATPPSQAPPSMTTPP---MQAPPSLQTIPPIQVPHSLTSPSLQAP 403
Query: 940 ITQEGMSAVAGF----SPEWAALA--ITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVR 993
+ +S++ SP A +T+ + + P PA+T P+ P A
Sbjct: 404 PSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPAST--PPDSPPLQAP- 460
Query: 994 VSTPEEPASPAAAVPTPEEPTSPAAAVP----------TPEEPTSPAAAVPPPEEPTSPA 1043
+S P P + P +SP P +P+ P S + + PP E S
Sbjct: 461 LSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLS--SLIMPPLETQSSL 518
Query: 1044 AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE 1103
A P +P A++ TP P+ A P + ++P + TP T P A +
Sbjct: 519 A----PPSLQTPPASLTTPPLENLPSLAPPPLQTASAP---LTTPHLETPPCPAPCPLQA 571
Query: 1104 PTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEE-PAFPAPAVPTPEESASAAVA 1162
P SP P PE P+S + TP A PA A P + P+ P + TP A +A
Sbjct: 572 PPSPLTT-PPPETPSS----IATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLA 626
Query: 1163 VPTPEESASPAAAVP-----TPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTS 1217
+P + SP A+ P TP+ A A V L+ P SP S P A S
Sbjct: 627 LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS 686
Query: 1218 PAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTP 1277
P+A+ P S+ P SLAA + P SP A+ P T A P L++P VP P
Sbjct: 687 PSAT-PPSQAPPSLAAPPL--QVPPSPPASPPMSPSATPPPQA---PPPLAAPPLQVP-P 739
Query: 1278 EEPASPAAAVSNLEEP------ASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPMEE 1331
PASP + S P A+P VP A++P + + P A PA A PP++
Sbjct: 740 SPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQA 799
Query: 1332 V--SPIGVPFLGVSAHTDSVPISEEGTP 1357
+ P P + + S+P+S TP
Sbjct: 800 LPSPPASFPGQAPFSPSASLPMSPLATP 827
Score = 115 bits (289), Expect = 2e-25
Identities = 141/545 (25%), Positives = 206/545 (37%), Gaps = 91/545 (16%)
Query: 832 QRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASIVSL 891
Q P + +P ++ A PS + + P E + +L P P + ++ ++
Sbjct: 501 QAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLEN---LPSLAPPPLQT--ASAPLTT 555
Query: 892 EEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAA----AITQEGMSA 947
+ P +A +T PE +++A + P + PA+A+ + +S
Sbjct: 556 PHLETPPCPAPCPLQAPPSPLTTPPPETPSSIA--TPPPQAPPALASPPLQGLPSPPLSP 613
Query: 948 VAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRV-----STPEEPAS 1002
+A P+ P+ P P +P+ P+ AV + S P P
Sbjct: 614 LATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPV 673
Query: 1003 PAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVP-----TPEEPTSPAA 1057
A P P SP+A TP P+ A PP + P SP A+ P TP P
Sbjct: 674 QAPFSPPASPPVSPSA---TPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPL 730
Query: 1058 AVPTPEEPTSPAAAVP-----TPEEPTSPAAAVPTPEEPTSPAA-------AVPTPEEP- 1104
A P + P SP A+ P TP P A P + P SP A A P P+ P
Sbjct: 731 AAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPP 790
Query: 1105 ---TSPAAAVPTP------EEPASPAAAVP-----TPEEPASPAAAVP----TPEEPAFP 1146
T P A+P+P + P SP+A++P TP A P A P P PA P
Sbjct: 791 ALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASP 850
Query: 1147 A------PAVPTPEESAS------AAVAVPTPEESASPAAAVPTPAESASFAAVVATLEE 1194
P P P+ S S A P P S SP++ + P + ++ +T EE
Sbjct: 851 TLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEE 910
Query: 1195 -------PTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTS-PAA 1246
P AA+ P P A +A PAA S PA A P P P A
Sbjct: 911 LRGYDSGPEGGAAASPPPDAELAACH----PAA---WSRGPAPPLAFRGAPGAPLPWPPA 963
Query: 1247 AVPTLEEPTSSAAAVLTPEELSSPAASVPTP---EEPASPAAAVSNLEEPASPAAAVPTP 1303
P SA + T E P ++ P P + SP + A A+ +P
Sbjct: 964 TGP------GSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSP 1017
Query: 1304 EVAAI 1308
+ A +
Sbjct: 1018 KQARL 1022
Score = 104 bits (259), Expect = 7e-22
Identities = 131/531 (24%), Positives = 198/531 (37%), Gaps = 77/531 (14%)
Query: 897 TAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEG-MSAVAGFSPEW 955
T + P + P P + + A+ S E +PA + G + A S
Sbjct: 185 TEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS 244
Query: 956 AALAITVPITEED---GTPEGPVTPATTVHAPEEPDTAAVR---VSTPEEPASPA----- 1004
+A ++ P GTP P P+ P+ A+R V+ P + A+PA
Sbjct: 245 SATPLSSPARSGPSARGTPRAPAHPSQ----PKPKGLQALRPPQVTPPRKDAAPALGPLS 300
Query: 1005 -AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPT-- 1061
+ + TP + A VP P+ +P A PP SP A P P P SP+A
Sbjct: 301 SSPLATPSPSGTKARPVPPPDNAATPLPATLPP----SPPLATPLPLAPPSPSAPPSLQT 356
Query: 1062 -PEEPTSPAAAVPTPEEPTSPAAAVPT---------PEEPTSPAA-AVPTP--------- 1101
P P +P + P P T P A P+ P TSP+ A P+P
Sbjct: 357 LPSPPATPPSQAP-PSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQAT 415
Query: 1102 ---EEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESAS 1158
PT A P A++ +P PAS P + P PA P + S S
Sbjct: 416 TSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAP-LSLPASPPLQTSLS 474
Query: 1159 AAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSP 1218
AV+ + + P A+ + A + A + + + P +S+ P+ T P
Sbjct: 475 PAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPP 534
Query: 1219 AASVPTSEEPA--SLAAAVSNPEEPTSPAAAVPTLEEPTS--------SAAAVLTPEELS 1268
++P+ P + +A ++ P T P A L+ P S + +++ TP +
Sbjct: 535 LENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQA 594
Query: 1269 SPAASVP--------------TPEEPASPAAAVSNLEEPASPAAAVP-----TPEVAAIP 1309
PA + P TP A P A+ L+ P SP A+ P TP A
Sbjct: 595 PPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPN 654
Query: 1310 AASVPTPEVPAIPAAAVPPMEEVSPIGVPFLGVSAHTDSVPISEEGTPVLE 1360
A +V + P P + P SP P + SA S P L+
Sbjct: 655 ALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ 705
Score = 95.1 bits (235), Expect = 4e-19
Identities = 104/434 (23%), Positives = 161/434 (37%), Gaps = 62/434 (14%)
Query: 983 APEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAA-----VPTPEEPTSPAAAVPPPE 1037
A E P +A+ + + P P+P AA +P P P P
Sbjct: 147 ATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPR 206
Query: 1038 EPTSPAA----AVPTPEEPTSPAA---------------AVPTPEEPTSPAAAVPTPEEP 1078
+ S A+ P+P P+A A P S +A TP P
Sbjct: 207 KSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAP 266
Query: 1079 TSPAAAVPTPEEPTSPAAAVPTPEEPTSPA------AAVPTPEEPASPAAAVPTPEEPAS 1132
P+ P + P P P + +PA + + TP + A VP P+ A+
Sbjct: 267 AHPSQPKPKGLQALRPPQVTP-PRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAAT 325
Query: 1133 PAAAVPTPEEP-AFPAPAVPTPEESASAAVAVP----TPEESASPAAAVPTPAESASFAA 1187
P A P P A P P P + + +P TP A P+ P P ++
Sbjct: 326 PLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTP-PMQAPPSLQ 384
Query: 1188 VVATLEEP---TSPAASVPTPAAMVATLEEFTSPAASVPTSE--------EPASLAAAVS 1236
+ ++ P TSP+ P +++L+ TS + PT + P A+++
Sbjct: 385 TIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGS--PTLQATHSFLTMSPRQTQASLT 442
Query: 1237 NPEEPTSPAAAVPTLEEPTSSAAA-----VLTP--EELSSPAASVPTPEEPA----SPAA 1285
+P P S P L+ P S A+ L+P LSSP P + SP A
Sbjct: 443 SPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQA 502
Query: 1286 AVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPMEEVS-PIGVPFLGVSA 1344
+S+L P + P P AS+ TP + +P+ A PP++ S P+ P L
Sbjct: 503 PLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPP 562
Query: 1345 HTDSVPISEEGTPV 1358
P+ +P+
Sbjct: 563 CPAPCPLQAPPSPL 576
Score = 88.6 bits (218), Expect = 4e-17
Identities = 103/370 (27%), Positives = 139/370 (37%), Gaps = 37/370 (10%)
Query: 1000 PASPAAAVPTPEEPTSPAAAVP-TPEEPTSPAAAVPPPEEPTSP-AAAVPTPEEPTSPAA 1057
PA+ A + TP P SP P TP AA +P + A + P S
Sbjct: 17 PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76
Query: 1058 AVPTPEEPTS---PAAAVPTPEE-PTSPAAAVPTPEEPTSPAAAVPTPEE-PTSPAAAVP 1112
A PT TS PA+ P +P A +P +SP A T P
Sbjct: 77 AGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRI 136
Query: 1113 TPEEPASPAAAVPTPEEPASPAAAV--PTPEEPAFPAPAVPTPEESASAAVAVPTPEESA 1170
+ EE + A P+ A A A + P P+PA+ +A V +P P SA
Sbjct: 137 SAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSA 196
Query: 1171 SPAAAVPTPAESASFAAVVATLEEPTSPAA----------SVPTPAAMVATLEEFTSPAA 1220
P P +S S A+ +T E SPAA P ++ ++ +SPA
Sbjct: 197 RPRPPTEGPRKSVSSASEHSTTE--PSPAARRRPSAGGGLQRPASRSLSSSATPLSSPAR 254
Query: 1221 SVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVL---------TPEELSSPA 1271
S P++ A S P+ A P + P AA L TP + A
Sbjct: 255 SGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKA 314
Query: 1272 ASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAA--SVPT-PEVPAIPAAAVPP 1328
VP P+ A+P A P SP A P P P+A S+ T P PA P + PP
Sbjct: 315 RPVPPPDNAATPLPATL----PPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPP 370
Query: 1329 MEEVSPIGVP 1338
P+ P
Sbjct: 371 SMTTPPMQAP 380
Score = 34.3 bits (77), Expect = 0.88
Identities = 51/202 (25%), Positives = 67/202 (33%), Gaps = 15/202 (7%)
Query: 1108 AAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAF-----PAPAV-PTPEESASAAV 1161
A A PA+ A + TP P SP P P PA A AV P + +
Sbjct: 8 AKAGAAARTPAARAPGLLTPRPPGSPRP--PPPVTPAALRVLGAAGAVGRKPLAERAGGI 65
Query: 1162 AVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAAS 1221
T ESA A P SA ++ P S PA + + AS
Sbjct: 66 GGATIPESAPRAG----PTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRAS 121
Query: 1222 VPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPA 1281
T P + EE + A E P SA + + S P P+P
Sbjct: 122 GTTRPGPLGQKGLRISAEETVARGKAT---EAPKRSALSAGARRDTSGPTPGTPSPAMAR 178
Query: 1282 SPAAAVSNLEEPASPAAAVPTP 1303
AA + + P +A P P
Sbjct: 179 RSRAAGTEVGLPRPAPSARPRP 200
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 127 bits (318), Expect = 1e-28
Identities = 117/412 (28%), Positives = 154/412 (37%), Gaps = 58/412 (14%)
Query: 962 VPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVP 1021
+ + E+ PE P P T V P P PA A P P+ P +P VP
Sbjct: 10476 IVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEA-PPPKVPEAPKEVVP 10534
Query: 1022 TPEEPTSPAAA--VPPPEEPTSPAAAVPTPEEPTS--PAAAVPTPEEPTSPAAAVPTPEE 1077
+ P P VPP + P P AAVP + P + P P PE P +P VP +
Sbjct: 10535 EKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKV 10594
Query: 1078 PTSPA----------------------AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPE 1115
P +P VP P++P VP + P P AVP
Sbjct: 10595 PAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKP-----EVPPTKVPEVPKVAVP--- 10646
Query: 1116 EPASPAAAVPTPEEPASPAAAVPTPEEPAF---PAPAVPTPEESASAAVAVPTPE---ES 1169
E P A P PE P P PEE A PA V PE +A V VP + E
Sbjct: 10647 EKKVPEAIPPKPESP--PPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEK 10704
Query: 1170 ASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPA 1229
+PA P + ++ P P VP + ++ +P A VP +
Sbjct: 10705 KAPAVVAKKPE--------LPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEV 10756
Query: 1230 SLAAAVSNPEEPTSPAAAVPTLEEP--TSSAAAVLTPEELSSPAASVPTPEEPASPAAAV 1287
V+ P++P P A VP + + AV PE SP V E +P +
Sbjct: 10757 VPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEI 10816
Query: 1288 SNLEEPASPAA-----AVPTPEVAAIPAASVPTPEVPAIPAAAVPPMEEVSP 1334
+ EE P A VP P V P +P +VP I PP +E P
Sbjct: 10817 APEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEP 10868
Score = 120 bits (302), Expect = 7e-27
Identities = 168/578 (29%), Positives = 211/578 (36%), Gaps = 81/578 (14%)
Query: 813 QVTKAGNTEPVLEEWIPVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVV 872
+V KA E + E IP P + P V +A +P + + A P P+ V
Sbjct: 10555 EVPKAAVPEKKVPEAIP----PKPESPPPEVPEAPKEVVPEKK----VPAAP-PKKPEVT 10605
Query: 873 AALVPFPHEDILVASIVSLEEEDVTAAAVSAPE--RATVPAVT-VSVPEGTAAVAAVSSP 929
VP ++++ E+ V PE VP V V+VPE A P
Sbjct: 10606 PVKVPEAPKEVV-------PEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKP 10658
Query: 930 EETAPAV---AAAITQEGMSAVAGFSPEWAALA-ITVPITEEDGTPEGPV----TPATTV 981
E P V + E A PE AA +TVP P+ PV PA
Sbjct: 10659 ESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVP-------PKKPVPEKKAPAVVA 10711
Query: 982 HAPEEPDTAAVRVSTPEEPAS--PAAAVP--TPEEPTSPAAAVPTPEEPTSPAAAVPPPE 1037
PE P V PE P P VP P++P +P A VP + P V P+
Sbjct: 10712 KKPELPP-----VKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPK 10766
Query: 1038 EPTSPAAAVP-TPEEPT-SPAAAVPTPEEPTSPAAAVP------TPEEPTSPAAAVPTP- 1088
+P P A VP P++P AVP PE SP V PEE +P P P
Sbjct: 10767 KPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPV 10826
Query: 1089 ---EEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAF 1145
EEP P AVP + P VP ++P +P P PE+ P P P
Sbjct: 10827 AEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPP- 10885
Query: 1146 PAPAVPTPEESASAAVAVP---TPEESASPAAAVPTPAESASFAAVVATL--EEPTSPAA 1200
PAP +E A+P PE+ P TP + V L E P
Sbjct: 10886 PAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKE 10945
Query: 1201 SVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAA 1260
V + + EE P E+ A PE P P V +E PT +
Sbjct: 10946 EVVLKSVLRKRPEE-EEPKVEPKKLEKVKKPAV----PEPP--PPKPVEEVEVPTVTKRE 10998
Query: 1261 VLTPEELS----SPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTP 1316
PE PA +P PE P A V ++ P P PTP AA V P
Sbjct: 10999 RKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPP--PVEPEPTP-----IAAPVTVP 11051
Query: 1317 EVPAIPAAAVPPMEEVSPIGVPFLGVSAHTDSVPISEE 1354
V A P E P G P GV T S PI E
Sbjct: 11052 VVGKKAEAKAPKEEAAKPKG-PIKGVPKKTPS-PIEAE 11087
Score = 120 bits (300), Expect = 1e-26
Identities = 152/570 (26%), Positives = 206/570 (36%), Gaps = 76/570 (13%)
Query: 820 TEPVLEEWIPVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFP 879
TEP E+ IPV +P VPT A A + VP P+ VP
Sbjct: 9787 TEP--EKPIPV--KPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEE 9842
Query: 880 ----HEDILVASIVSLEEEDVTAAAVSAP---------ERATVPAVTVSVPEGTAAVAAV 926
E+ + SI E+E VT A P E+ VP V+ P V
Sbjct: 9843 PKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKE 9902
Query: 927 SSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEE 986
PEE A +E ++ V + E I EE+ E V P V PE
Sbjct: 9903 LEPEEVA------FEEEVVTHVEEYLVEEEEEYIH---EEEEFITEEEVVPVIPVKVPEV 9953
Query: 987 PDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVP-TPEEPTSPAAAVPPPEEPTSPAAA 1045
P R PEE VP P++ +P A VP P++P + P +E PA
Sbjct: 9954 P-----RKPVPEEKKP----VPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKV 10004
Query: 1046 VPTPEEPT-SPAAAVPTPEEPTSPAAAVP-TPEEPT-SPAAAVPTPEEPTSPAAAVPTPE 1102
P++P VP P++ +P A VP P++P VP P++ +P A VP
Sbjct: 10005 PEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVP 10064
Query: 1103 EPTSPAAAVPTP--EEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAA 1160
+ P PTP ++ +P VP EP A+P EE F VP E
Sbjct: 10065 KKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEE 10124
Query: 1161 VAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAA 1220
+P EE +P E V+ EE VP V EEF
Sbjct: 10125 EVLPEEEE------VLPEEEE------VLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEE 10172
Query: 1221 SVPTSEEPASLAAAVSN------------PEEPTSPAAAVPTLEEPTSSAAAVLTPEELS 1268
+P + + A V P++ +P A VP + + +L EE
Sbjct: 10173 VLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEV 10232
Query: 1269 SPAASVPTPEE--------PASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPA 1320
P PEE P P + + +EE A P VP A+P A P P+
Sbjct: 10233 LPVEVTEEPEEEPISEEEIPEEPPS-IEEVEEVAPPR--VPEVIKKAVPEAPTPVPKKVE 10289
Query: 1321 IPAAAVPPMEEVSPIGVPFLGVSAHTDSVP 1350
P A V + VP A VP
Sbjct: 10290 APPAKVSKKIPEEKVPVPVQKKEAPPAKVP 10319
Score = 119 bits (299), Expect = 2e-26
Identities = 159/568 (27%), Positives = 204/568 (35%), Gaps = 93/568 (16%)
Query: 811 EKQVTKAGNTEPVLE-EWIPVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGT 869
E +V K V E E + V ++P P + + + +P + T + P
Sbjct: 10412 EHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEKI---IPPKKPPTKVVPRKEPP-- 10466
Query: 870 AVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSP 929
A VP + I+V V + EE PE +P V VPE V P
Sbjct: 10467 ----AKVPEVPKKIVVEEKVRVPEEP-RVPPTKVPE--VLPPKEV-VPEKKVPVPPAKKP 10518
Query: 930 EETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDT 989
E P V A P+ VP+ P+ P P T V PE P
Sbjct: 10519 EAPPPKVPEA-------------PKEVVPEKKVPVPP----PKKPEVPPTKV--PEVPKA 10559
Query: 990 AAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAA--VPPPEEPTSPAAAVP 1047
A PE P P PE P +P VP + P +P V P + P +P VP
Sbjct: 10560 AVPEKKVPEA-IPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVP 10618
Query: 1048 T-------PEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPT 1100
P++P VP + P P AVP E P A P PE P P
Sbjct: 10619 EKKVPVPPPKKP-----EVPPTKVPEVPKVAVP---EKKVPEAIPPKPESP--PPEVFEE 10668
Query: 1101 PEE---PTSPAAAVPTPEEPASPAAAVPTPEEPA----SPAAAVPTPEEPAFPAPAVPTP 1153
PEE PA V PE A P VP P++P +PA PE P P VP
Sbjct: 10669 PEEVALEEPPAEVVEEPEPAAPPQVTVP-PKKPVPEKKAPAVVAKKPELPPVKVPEVP-K 10726
Query: 1154 EESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLE 1213
E V + P++ +P A VP + VA ++P P A VP LE
Sbjct: 10727 EVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVP-EVPKKPVLE 10785
Query: 1214 EFTSPAASVP---------TSEEPASLA------------AAVSNPEEPTSPAAAVPTLE 1252
E PA VP EEP +A V+ EEP P AVP E
Sbjct: 10786 E--KPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVP--E 10841
Query: 1253 EPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEV--AAIPA 1310
EP P + P A P EP P P A P +V
Sbjct: 10842 EPKKIIPEKKVP-VIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQL 10900
Query: 1311 ASVPTPEVPAIPAAAVPPMEEVSPIGVP 1338
++P +VP P VP E++P+ VP
Sbjct: 10901 KAIPKKKVPEKP--QVPEKVELTPLKVP 10926
Score = 97.4 bits (241), Expect = 8e-20
Identities = 115/444 (25%), Positives = 148/444 (33%), Gaps = 61/444 (13%)
Query: 960 ITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAA 1019
+ VPI ++ P P P EE ++ E+ PAA VP +
Sbjct: 9824 VPVPIPKKLKPPP-PKVPEEPKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEK 9882
Query: 1020 VPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPT 1079
VP P + +P VP + P E T + EE EE
Sbjct: 9883 VPVPRKEVAPPVRVPEVPKELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEV 9942
Query: 1080 SPAAAVPTPEEPTSPA----AAVPTPEEPTSPAAAVPTPEEPASPAAAVPT--PEEPASP 1133
P V PE P P VP P++ +P A V PE P P VP P++ P
Sbjct: 9943 VPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKV--PEVPKKPEEKVPVLIPKKEKPP 10000
Query: 1134 AAAVPTPEEPAFPAP----AVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVV 1189
A V PE P P P VP P++ + VP + P VP PA A
Sbjct: 10001 PAKV--PEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPA 10058
Query: 1190 ATLEEPTS--PAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSN---------- 1237
E P P PTP ++ +P VP EP + A+
Sbjct: 10059 KVPEVPKKLIPEEKKPTPVP-----KKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEI 10113
Query: 1238 -PEEPTSP--AAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPA 1294
PEE P +P EE VL EE P PEE P EE
Sbjct: 10114 VPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEV 10173
Query: 1295 SPAAAVPTPEVAAIP---------------AASVPTPEVPAIPAAA------VPPMEEVS 1333
P P A +P P +VP +P +P EEV
Sbjct: 10174 LPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVL 10233
Query: 1334 PIGVPFLGVSAHTDSVPISEEGTP 1357
P+ V+ + PISEE P
Sbjct: 10234 PV-----EVTEEPEEEPISEEEIP 10252
Score = 88.6 bits (218), Expect = 4e-17
Identities = 125/471 (26%), Positives = 163/471 (34%), Gaps = 80/471 (16%)
Query: 891 LEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAA---AITQEGMSA 947
+EEE V V + VP P + E PAV I++E M
Sbjct: 9196 MEEEKVQVTKVPEVSKKIVPQKPSRTPVQEEVI------EVKVPAVHTKKMVISEEKMFF 9249
Query: 948 VAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAV 1007
+ E +++TVP +++ E + A + P PE P PA
Sbjct: 9250 ASHTEEE---VSVTVPEVQKEIVTEEKIHVAISKRVEPPP-------KVPELPEKPA--- 9296
Query: 1008 PTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTS 1067
PEE A VP P++ PA VP + P P P PAA PE P
Sbjct: 9297 --PEE----VAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKK 9350
Query: 1068 PA----AAVPTPEEPTSPAAAVPTPEE--PTSPAAAVPTPEEPTSPAAAVPTPEEPASPA 1121
P VP ++ +P A VP ++ T + T E + P P P P
Sbjct: 9351 PVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREES------PPPAVPEIPK 9404
Query: 1122 AAVPTPEEPASPAAAVPTPEEPAFPA-PAVPTPEESASAAVAVPTPEESASPAAAVPTPA 1180
VP +P P P P PA P P PEE VAVP P A P P
Sbjct: 9405 KKVPEERKPV-PRKEEEVPPPPKVPALPKKPVPEEK----VAVPVP-----VAKKAPPPR 9454
Query: 1181 ESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEE 1240
S VV S P + T E S SEE ++ +V EE
Sbjct: 9455 AEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHE-VSAEEEWSYSEEEEGVSISVYREEE 9513
Query: 1241 PTSPAAAVPT----LEEP----TSSAAAVLTPEELSSPAASVPTPE-----EPASPAAAV 1287
A T +EEP +++ + PA E +P PA
Sbjct: 9514 REEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQEKKIVLKPKIPA--- 9570
Query: 1288 SNLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPMEEVSPIGVP 1338
+EEP P A VP +P VP P VP E+V P VP
Sbjct: 9571 -KIEEP--PPAKVPEAPKKIVPEKKVPAP---------VPKKEKVPPPKVP 9609
Score = 87.8 bits (216), Expect = 7e-17
Identities = 107/405 (26%), Positives = 139/405 (34%), Gaps = 75/405 (18%)
Query: 999 EPASPAAAVPTPEEPTSPAAAVPT-PEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAA 1057
EP P P PEEP VPT P+ P + PEE VP P++ P
Sbjct: 9788 EPEKPIPVKPVPEEP------VPTKPKAPPAKVLKKAVPEEKVP----VPIPKKLKPPPP 9837
Query: 1058 AVPTP-----EEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVP 1112
VP EE + E+ T PAA VP + VP P + +P VP
Sbjct: 9838 KVPEEPKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVP 9897
Query: 1113 ------TPEEPASPAAAVP--------------------TPEEPASPAAAVPTPEEPAFP 1146
PEE A V EE P V PE P P
Sbjct: 9898 EVPKELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKP 9957
Query: 1147 APAVPTPEESASAAVAVPTPEESASPAAAVP-TPAESASFAAVVATLEE-------PTSP 1198
P P VP P++ +P A VP P + V+ +E P P
Sbjct: 9958 VPEEKKP---------VPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVP 10008
Query: 1199 AASVPTPAAMVATLEEFTSPAASVP-TSEEPA-SLAAAVSNPEEPTSPAAAVPTLEEPTS 1256
VP V ++ +P A VP ++P V P++ +P A VP + +
Sbjct: 10009 KKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKK-- 10066
Query: 1257 SAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTP 1316
L PEE P P++ +P V EP A+P E VP
Sbjct: 10067 -----LIPEE----KKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEE 10117
Query: 1317 EVPAIPAAAVPPMEEVSPIGVPFLGVSAHTDSVPISEEGTPVLEE 1361
EV +P EEV P L + +P EE P EE
Sbjct: 10118 EVLPEEEEVLPEEEEVLPEEEEVL---PEEEEIPPEEEEVPPEEE 10159
Score = 71.6 bits (174), Expect = 5e-12
Identities = 132/525 (25%), Positives = 166/525 (31%), Gaps = 148/525 (28%)
Query: 808 IFPEKQVTKAGNTEP--------------VLEEWIPVLQRPSRTAAVPTVKDALDAALPS 853
+ PEK+V A +P V E+ +PV P + VP K +
Sbjct: 10588 VVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPV--PPPKKPEVPPTKVPEVPKVAV 10645
Query: 854 PEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVT 913
PE+ A P PE P E V+LEE A V PE A P VT
Sbjct: 10646 PEKKVPEAIPPKPESP---------PPEVFEEPEEVALEEPP--AEVVEEPEPAAPPQVT 10694
Query: 914 VS----VPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDG 969
V VPE A PE P + +E + PE + + VP E
Sbjct: 10695 VPPKKPVPEKKAPAVVAKKPE-LPPVKVPEVPKEVV-------PE-KKVPLVVPKKPEAP 10745
Query: 970 ---TPEGP--VTPATTVHAPEEPDTAAVRVSTPEEPASPAA----AVPTPEEPTSPAAAV 1020
PE P V P V P++P+ +V PE P P AVP PE SP V
Sbjct: 10746 PAKVPEVPKEVVPEKKVAVPKKPEVPPAKV--PEVPKKPVLEEKPAVPVPERAESPPPEV 10803
Query: 1021 -------------------PTP----EEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAA 1057
P P EEP P AVP + P VP ++P +P
Sbjct: 10804 YEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPP 10863
Query: 1058 AVPTPEE----------PTSPAAAVP------------------TPEEPTSPAAAVPTP- 1088
P PE+ P P A P PE+P P TP
Sbjct: 10864 KEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPL 10923
Query: 1089 ------------------------------------EEPTSPAAAVPTPEEPTSPAAAVP 1112
EEP + ++P P P
Sbjct: 10924 KVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPP 10983
Query: 1113 TPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPA-VPTPEESASAAVAVPTP-EESA 1170
P E T E P +PA P PA P P+ A P P E
Sbjct: 10984 KPVEEVE--VPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEP 11041
Query: 1171 SPAAA---VPTPAESASFAAVVATLEEPTSPAASVP--TPAAMVA 1210
+P AA VP + A A +P P VP TP+ + A
Sbjct: 11042 TPIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIEA 11086
Score = 70.9 bits (172), Expect = 8e-12
Identities = 107/450 (23%), Positives = 146/450 (32%), Gaps = 50/450 (11%)
Query: 808 IFPEKQVTKAGNTEPVLEEWIPVLQRP-----SRTAAVPTVKDALDAALPS-PEEGTSIA 861
I E++ PV+ +P + R + VP K+A A +P P++
Sbjct: 9930 IHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKV 9989
Query: 862 AVPAPEGTAVVAALVP-FPHEDILVASIVSLEEEDVTAAAVSAPE--RATVPAVTVSVPE 918
V P+ A VP P + + + + V A PE + VP V VP
Sbjct: 9990 PVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVP- 10048
Query: 919 GTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTPA 978
A V +P P V + E VP E P+ P
Sbjct: 10049 ---APKKVEAPPAKVPEVPKKLIPEEKKPTP------------VPKKVEAPPPKVPKKRE 10093
Query: 979 TT---VHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPP 1035
V P+E + PEE P PEE +P EE +PP
Sbjct: 10094 PVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEEEE----VLPEEEEVLPEEEEIPP 10149
Query: 1036 PEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPE---EPTSPAAAVPTPEEPT 1092
EE P EE P V +P P A P PE + T +P EE
Sbjct: 10150 EEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPA-PVPEIKKKVTEKKVVIPKKEE-- 10206
Query: 1093 SPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPA-------F 1145
+P A VP + + EE P PEE P + PEEP
Sbjct: 10207 APPAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEE--EPISEEEIPEEPPSIEEVEEV 10264
Query: 1146 PAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTP 1205
P VP + A P P++ +P A V V E P + VP
Sbjct: 10265 APPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKK 10324
Query: 1206 A---AMVATLEEFTSPAASVPTSEEPASLA 1232
++ +E PA EE S+A
Sbjct: 10325 VPEKKVLVPKKEAVPPAKGRTVLEEKVSVA 10354
Score = 60.5 bits (145), Expect = 1e-08
Identities = 126/555 (22%), Positives = 175/555 (31%), Gaps = 87/555 (15%)
Query: 821 EPVLEEWIPV---LQRPSRTAAVPTVKDAL----DAALPSPEEGTSIAAVPAPEGTAVVA 873
+PV EE IPV ++ + A VP V+ + + + E + AVP V
Sbjct: 9350 KPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKVPE 9409
Query: 874 ALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETA 933
P P + EEE V A + VP V+VP A A E +
Sbjct: 9410 ERKPVPRK----------EEEVPPPPKVPALPKKPVPEEKVAVPVPVAKKAPPPRAEVSK 9459
Query: 934 PAVA------------------AAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPV 975
V +T+ +SA +S +++ + E+ E
Sbjct: 9460 KTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEEEGVSISVYREEEREEEEE 9519
Query: 976 TPATTVHAPEEPDTAAVR----VSTPEEPASPAAAVPTPEEPTSPAAAVPTP-EEPTSPA 1030
T EEP+ V + + A PA E+ +P EEP
Sbjct: 9520 AEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQEKKIVLKPKIPAKIEEP---- 9575
Query: 1031 AAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE 1090
PP + P +P VP + P A VP E+ VP P+ P P VP +
Sbjct: 9576 ---PPAKVPEAPKKIVPEKKVP----APVPKKEK-------VPPPKVPEEPKKPVPEKKV 9621
Query: 1091 PTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAV 1150
P V EEP + V ++ A P A VP + A P V
Sbjct: 9622 PPK----VIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPKRAVPEEKV 9677
Query: 1151 ----PTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPA 1206
P EE A V ++ P V +EE A ++ A
Sbjct: 9678 LKLKPKREEEPPAKVTEFRKRVVKEEKVSIEAPKREPQPIKEVTIMEEKER-AYTLEEEA 9736
Query: 1207 AMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPT----SSAAAVL 1262
V EE+ EE EPT EE +
Sbjct: 9737 VSVQREEEY----------EEYEEYDYKEFEEYEPTEEYDQYEEYEEREYERYEEHEEYI 9786
Query: 1263 TPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIP 1322
T E P VP P P A + + + A P VP P IP P P P +P
Sbjct: 9787 TEPEKPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVP----IPKKLKPPP--PKVP 9840
Query: 1323 AAAVPPMEEVSPIGV 1337
EE I +
Sbjct: 9841 EEPKKVFEEKIRISI 9855
Score = 51.6 bits (122), Expect = 5e-06
Identities = 100/405 (24%), Positives = 123/405 (30%), Gaps = 79/405 (19%)
Query: 808 IFPEKQVT----KAGNTEPVLEEWIPVLQRPSRTAAVPTVKDALDAALPSPEEGTSIA-- 861
+ PEK+V K P +P P + AVP + A +P + +
Sbjct: 10728 VVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEK 10787
Query: 862 -AVPAPEGTAVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVPEGT 920
AVP PE V E+I ++ EEE A PAV PE
Sbjct: 10788 PAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAV----PEEP 10843
Query: 921 AAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTPATT 980
+ PE+ P + A PE I P + P P P
Sbjct: 10844 KKII----PEKKVPVIKKP------EAPPPKEPE-PEKVIEKPKLKPRPPPPPPAPPKED 10892
Query: 981 VHAPEEPDTAAVRVSTPEEPASPAAAVPTP---------------EEPTSPAAAV----- 1020
V A + PE+P P TP E P V
Sbjct: 10893 VKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSV 10952
Query: 1021 ----PTPEEPT----------SPAAAVPPPEEPTSPAAAVPTPE-------EPTS----- 1054
P EEP PA PPP +P VPT EPT
Sbjct: 10953 LRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVE-VPTVTKRERKIPEPTKVPEIK 11011
Query: 1055 PAAAVPTPEEPTSPAAAV------PTPEEPTSPAAAVPTPEEPTSPAAAVPTPE--EPTS 1106
PA +P PE P A V P EPT AA V P A P E +P
Sbjct: 11012 PAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKG 11071
Query: 1107 PAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVP 1151
P V P++ SP A P S P + AVP
Sbjct: 11072 PIKGV--PKKTPSPIEAERRKLRPGSGGEKPPDEAPFTYQLKAVP 11114
Score = 40.8 bits (94), Expect = 0.009
Identities = 35/102 (34%), Positives = 42/102 (41%), Gaps = 16/102 (15%)
Query: 1013 PTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAV 1072
P P + VP P T P AVPP E P P A P P +PTPEE P +
Sbjct: 8935 PDIPDSRVPIP---TMPIRAVPPEEIP--PVVAPPIP-------LLLPTPEEKKPPPKRI 8982
Query: 1073 PTPEEPTSPAA--AVPTPEEPTSPAAAVPTPEEPTS--PAAA 1110
++ A V P+E T V P PT+ PA A
Sbjct: 8983 EVTKKAVKKDAKKVVAKPKEMTPREEIVKKPPPPTTLIPAKA 9024
Score = 39.7 bits (91), Expect = 0.021
Identities = 52/225 (23%), Positives = 83/225 (36%), Gaps = 18/225 (8%)
Query: 855 EEGTSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTV 914
E +S+ V + + T +L + H +LEE+ + + + + T+ A +
Sbjct: 32506 EASSSVREVKS-QMTETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTLAARIL 32564
Query: 915 SVP------EGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEED 968
+ P EG +A + + E P V + +S A T I+
Sbjct: 32565 TKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQ 32624
Query: 969 GTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTS 1028
+ EG + V E A T ++ AV +P SP V +PE S
Sbjct: 32625 ASDEGNYS---VVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKS 32681
Query: 1029 PAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVP 1073
P P EP+ P A PT +PT PT + P +A P
Sbjct: 32682 PKRVKSP--EPSHPKAVSPTETKPT------PTEKVQHLPVSAPP 32718
Score = 39.3 bits (90), Expect = 0.027
Identities = 64/278 (23%), Positives = 99/278 (35%), Gaps = 26/278 (9%)
Query: 984 PEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPA----AAVPTPEEPTSPAAAVPPPEEP 1039
PE+ T +V + A+ A + E PA V T + S + E
Sbjct: 168 PEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVSTAQISESRQTRIEKKIEA 227
Query: 1040 TSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVP 1099
A ++ T E AA P + P P P + PTP P+ A A
Sbjct: 228 HFDARSIATVEMVIDGAAGQQLPHKTP--------PRIPPKPKSRSPTP--PSIAAKAQL 277
Query: 1100 TPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASA 1159
++ SP P+P A P+P SPAA + T + +P + ++++
Sbjct: 278 ARQQSPSPIRHSPSPVRHVR--APTPSPVRSVSPAARISTSPIRSVRSPLLMRKTQASTV 335
Query: 1160 AVA--VPTP--EESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEF 1215
A VP P +E +++ E+ + EE V T+
Sbjct: 336 ATGPEVPPPWKQEGYVASSSEAEMRETTLTTSTQIRTEERWEGRYGVQEQ----VTISGA 391
Query: 1216 TSPAASVPTSEEPASLAAAVSNPE--EPTSPAAAVPTL 1251
AASV S A+ A A E + +AAV T+
Sbjct: 392 AGAAASVSASASYAAEAVATGAKEVKQDADKSAAVATV 429
Score = 38.9 bits (89), Expect = 0.036
Identities = 34/124 (27%), Positives = 53/124 (42%), Gaps = 10/124 (8%)
Query: 1208 MVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEEL 1267
+ T + T +SV S+E + + V N E A T+++ + AV +P +
Sbjct: 32609 VTTTKYKSTFEISSVQASDE-GNYSVVVEN-SEGKQEAEFTLTIQKARVTEKAVTSPPRV 32666
Query: 1268 SSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVP 1327
SP V +PE SP S EP+ P A PT PT +V +P +A P
Sbjct: 32667 KSPEPRVKSPEAVKSPKRVKS--PEPSHPKAVSPT------ETKPTPTEKVQHLPVSAPP 32718
Query: 1328 PMEE 1331
+ +
Sbjct: 32719 KITQ 32722
Score = 38.1 bits (87), Expect = 0.061
Identities = 44/150 (29%), Positives = 53/150 (35%), Gaps = 23/150 (15%)
Query: 1021 PTPEEPTSPAAAVPPPEEPTSPAAAVPTPEE-------PTSPAAAVPTPEEPTSPAAAVP 1073
P E S A + P E S A T +E P P + VP P T P AVP
Sbjct: 8897 PDDEGVYSVIARLEPRGEARSTAELYLTTKEIKLELKPPDIPDSRVPIP---TMPIRAVP 8953
Query: 1074 TPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTP----EEPASPAAAVPTPEE 1129
PEE P A P P +PTPEE P + ++ A A P
Sbjct: 8954 -PEE-IPPVVAPPIP-------LLLPTPEEKKPPPKRIEVTKKAVKKDAKKVVAKPKEMT 9004
Query: 1130 PASPAAAVPTPEEPAFPAPAVPTPEESASA 1159
P P P PA A + S+ A
Sbjct: 9005 PREEIVKKPPPPTTLIPAKAPEIIDVSSKA 9034
Score = 38.1 bits (87), Expect = 0.061
Identities = 40/123 (32%), Positives = 51/123 (41%), Gaps = 22/123 (17%)
Query: 985 EEPDTAAVRVSTPE------EPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEE 1038
E TA + ++T E P P + VP P T P AVP PEE +PP
Sbjct: 8914 EARSTAELYLTTKEIKLELKPPDIPDSRVPIP---TMPIRAVP-PEE-------IPPVVA 8962
Query: 1039 PTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAA--AVPTPEEPTSPAAAVPTPEEPTS--P 1094
P P +PTPEE P + ++ A V P+E T V P PT+ P
Sbjct: 8963 PPIP-LLLPTPEEKKPPPKRIEVTKKAVKKDAKKVVAKPKEMTPREEIVKKPPPPTTLIP 9021
Query: 1095 AAA 1097
A A
Sbjct: 9022 AKA 9024
Score = 34.3 bits (77), Expect = 0.88
Identities = 43/148 (29%), Positives = 52/148 (35%), Gaps = 18/148 (12%)
Query: 980 TVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEP 1039
T+H D V EP A + T P P P + VP P
Sbjct: 8891 TIHNVTPDDEGVYSVIARLEPRGEARSTAELYLTTKEIKLELKP--PDIPDSRVPIP--- 8945
Query: 1040 TSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAA--A 1097
T P AVP PEE P A P P +PTPEE P + ++ A
Sbjct: 8946 TMPIRAVP-PEE-IPPVVAPPIP-------LLLPTPEEKKPPPKRIEVTKKAVKKDAKKV 8996
Query: 1098 VPTPEEPTSPAAAVPTPEEPAS--PAAA 1123
V P+E T V P P + PA A
Sbjct: 8997 VAKPKEMTPREEIVKKPPPPTTLIPAKA 9024
Score = 33.5 bits (75), Expect = 1.5
Identities = 35/111 (31%), Positives = 42/111 (37%), Gaps = 21/111 (18%)
Query: 1065 PTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAV 1124
P P + VP P T P AVP PEE P A P P +PTPEE P +
Sbjct: 8935 PDIPDSRVPIP---TMPIRAVP-PEE-IPPVVAPPIP-------LLLPTPEEKKPPPKRI 8982
Query: 1125 PTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAA 1175
++ AV + P TP E V P P + PA A
Sbjct: 8983 EVTKK------AVKKDAKKVVAKPKEMTPREE---IVKKPPPPTTLIPAKA 9024
Score = 33.5 bits (75), Expect = 1.5
Identities = 25/68 (36%), Positives = 32/68 (47%), Gaps = 8/68 (11%)
Query: 1045 AVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEP 1104
AV +P SP V +PE SP V +P EP+ P A PT +PT PT +
Sbjct: 32659 AVTSPPRVKSPEPRVKSPEAVKSP-KRVKSP-EPSHPKAVSPTETKPT------PTEKVQ 32710
Query: 1105 TSPAAAVP 1112
P +A P
Sbjct: 32711 HLPVSAPP 32718
Score = 33.5 bits (75), Expect = 1.5
Identities = 25/68 (36%), Positives = 32/68 (47%), Gaps = 8/68 (11%)
Query: 1058 AVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEP 1117
AV +P SP V +PE SP V +P EP+ P A PT +PT PT +
Sbjct: 32659 AVTSPPRVKSPEPRVKSPEAVKSP-KRVKSP-EPSHPKAVSPTETKPT------PTEKVQ 32710
Query: 1118 ASPAAAVP 1125
P +A P
Sbjct: 32711 HLPVSAPP 32718
Score = 33.1 bits (74), Expect = 2.0
Identities = 37/114 (32%), Positives = 46/114 (40%), Gaps = 22/114 (19%)
Query: 1091 PTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAV 1150
P P + VP P T P AVP PEE P A P P +PTPEE P +
Sbjct: 8935 PDIPDSRVPIP---TMPIRAVP-PEE-IPPVVAPPIP-------LLLPTPEEKKPPPKRI 8982
Query: 1151 PTPEES----ASAAVAVP---TPEESASPAAAVPT---PAESASFAAVVATLEE 1194
+++ A VA P TP E PT PA++ V + EE
Sbjct: 8983 EVTKKAVKKDAKKVVAKPKEMTPREEIVKKPPPPTTLIPAKAPEIIDVSSKAEE 9036
Score = 32.7 bits (73), Expect = 2.6
Identities = 35/123 (28%), Positives = 47/123 (38%), Gaps = 7/123 (5%)
Query: 955 WAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEP--ASPAAAVPTPEE 1012
++ +A P E T E +T + PD RV P P A P +P
Sbjct: 8903 YSVIARLEPRGEARSTAELYLTTKEIKLELKPPDIPDSRVPIPTMPIRAVPPEEIPPVVA 8962
Query: 1013 PTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAA--AVPTPEEPTSPAAAVPTPEEPTS--P 1068
P P +PTPEE P + ++ A V P+E T V P PT+ P
Sbjct: 8963 PPIPLL-LPTPEEKKPPPKRIEVTKKAVKKDAKKVVAKPKEMTPREEIVKKPPPPTTLIP 9021
Query: 1069 AAA 1071
A A
Sbjct: 9022 AKA 9024
Score = 32.7 bits (73), Expect = 2.6
Identities = 25/68 (36%), Positives = 31/68 (45%), Gaps = 8/68 (11%)
Query: 1032 AVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEP 1091
AV P SP V +PE SP V +P EP+ P A PT +PT PT +
Sbjct: 32659 AVTSPPRVKSPEPRVKSPEAVKSP-KRVKSP-EPSHPKAVSPTETKPT------PTEKVQ 32710
Query: 1092 TSPAAAVP 1099
P +A P
Sbjct: 32711 HLPVSAPP 32718
Score = 31.6 bits (70), Expect = 5.7
Identities = 48/190 (25%), Positives = 67/190 (35%), Gaps = 35/190 (18%)
Query: 1158 SAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLE---- 1213
S +A PE+S + + A+ A + E PA T + E
Sbjct: 160 SLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVSTAQISESRQT 219
Query: 1214 ------EFTSPAASVPTSEEPASLAAAVSNPEE-----PTSPAAAVPTLEEPTSSAAAVL 1262
E A S+ T E AA P + P P + PT P+ +A A L
Sbjct: 220 RIEKKIEAHFDARSIATVEMVIDGAAGQQLPHKTPPRIPPKPKSRSPT--PPSIAAKAQL 277
Query: 1263 TPEELSSPA-----------ASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAA 1311
++ SP A P+P SPAA +S SP +V +P + A
Sbjct: 278 ARQQSPSPIRHSPSPVRHVRAPTPSPVRSVSPAARIS-----TSPIRSVRSPLLMRKTQA 332
Query: 1312 SVPT--PEVP 1319
S PEVP
Sbjct: 333 STVATGPEVP 342
Score = 30.8 bits (68), Expect = 9.7
Identities = 58/266 (21%), Positives = 92/266 (34%), Gaps = 31/266 (11%)
Query: 1115 EEPASPAAAVPTPEEPASPAAAVPTPEEP-AFPAPA---VPTPEESAS--AAVAVPTPEE 1168
+E S A P+ PAS VP +P AP+ + T ++ ++ T +
Sbjct: 738 KERISAAKVAEPPQRPASEPHVVPKAVKPRVIQAPSETHIKTTDQKGMHISSQIKKTTDL 797
Query: 1169 SASPAAAVPTPAESASFAAVVATLEEP-TSPAASVPTPAAMVATLEEFTSPAASVPTSEE 1227
+ V +AS V+ + P T + +ATL++ S +S +
Sbjct: 798 TTERLVHVDKRPRTASPHFTVSKISVPKTEHGYEASIAGSAIATLQKELSATSS--AQKI 855
Query: 1228 PASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAV 1287
S+ A P E A P + P + TP+ S A V +E
Sbjct: 856 TKSVKAPTVKPSETRVRAEPTPLPQFPFAD-----TPDTYKS-EAGVEVKKEVGVSITGT 909
Query: 1288 SNLEEPASPAAAVPTPEVAAIPAASVPTP-EVPAIPAAAVPPMEEVSPIGVPFLGVSAHT 1346
+ EE + E A VP P E+P P V ++ V+ I + + H
Sbjct: 910 TVREERFE---VLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHI 966
Query: 1347 DSVPISEEGTPVLEEASSTGMWIKED 1372
P S T W +ED
Sbjct: 967 SGYP------------SPTVTWYRED 980
Score = 30.8 bits (68), Expect = 9.7
Identities = 25/79 (31%), Positives = 38/79 (48%), Gaps = 13/79 (16%)
Query: 1308 IPAASVPTPEVP--AIPAAAVPPMEEVSPIGVPFLGVSAHTDSVPISEEGTPVLEEASST 1365
IP + VP P +P A+P +PP+ V+P +P L +P EE P + T
Sbjct: 8937 IPDSRVPIPTMPIRAVPPEEIPPV--VAP-PIPLL--------LPTPEEKKPPPKRIEVT 8985
Query: 1366 GMWIKEDLDSLVFGIKEVT 1384
+K+D +V KE+T
Sbjct: 8986 KKAVKKDAKKVVAKPKEMT 9004
Score = 30.8 bits (68), Expect = 9.7
Identities = 21/61 (34%), Positives = 24/61 (39%), Gaps = 3/61 (4%)
Query: 1097 AVPTPEEPTSPAAAVPTPEEPASPAAAV-PTPEEP--ASPAAAVPTPEEPAFPAPAVPTP 1153
AV +P SP V +PE SP P P P SP PTP E P P
Sbjct: 32659 AVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPVSAPP 32718
Query: 1154 E 1154
+
Sbjct: 32719 K 32719
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 855
Score = 122 bits (305), Expect = 3e-27
Identities = 137/474 (28%), Positives = 187/474 (39%), Gaps = 56/474 (11%)
Query: 889 VSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAV 948
+S EE A AP+R+ + A A S P P+ A A
Sbjct: 136 ISAEETVARGKATEAPKRSALSA---------GARRDTSGPTPGTPSPAMARRSRAAGTE 186
Query: 949 AGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVR-------VSTPEEPA 1001
G P A A P TE P V+ A+ H+ EP AA R + P +
Sbjct: 187 VGL-PRPAPSARPRPPTEG---PRKSVSSASE-HSTTEPSPAARRRPSAGGGLQRPASRS 241
Query: 1002 SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAV-- 1059
++A P S +A TP P P+ P + P P P + +PA
Sbjct: 242 LSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTP-PRKDAAPALGPLS 300
Query: 1060 PTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAA-AVPTPEEPTSPAAAVPTPEEPA 1118
+P SP+AA+ + PT PA TP + A P P P SP+A P+
Sbjct: 301 SSPLATPSPSAALQSQAPPTLPA----TPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPS 356
Query: 1119 SPAAAVPTPEEPASPAAAVPTPEE-----PAFPAPAVPTPEESASAAVAVPTPEESASPA 1173
PA TP A+ + PT + P+ P + TP A A+A+P + SP
Sbjct: 357 PPA----TPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPP 412
Query: 1174 AAVP-----TPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEP 1228
A+ P TP+ A A V L+ P SP S P A SP+A+ P S+ P
Sbjct: 413 ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSAT-PPSQAP 471
Query: 1229 ASLAAAV-----SNPEEPTSPAAAVPTLEEPTSSAAAVLT---PEELSSPAASVPTPEEP 1280
SLAA S P P +A P + P AA L P + PA + P +
Sbjct: 472 PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQAL 531
Query: 1281 ASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPMEEVSP 1334
SP A+ + P SP+A++P +A P + P V A P VPP SP
Sbjct: 532 PSPPASFPG-QAPFSPSASLPMSPLATPPPQA---PPVLAAPLLQVPPSPPASP 581
Score = 105 bits (263), Expect = 2e-22
Identities = 140/540 (25%), Positives = 212/540 (39%), Gaps = 82/540 (15%)
Query: 831 LQRPSRTAAVPTVKDALDAALPSPE-EGTSIAAV----PAPEGTAVVAALVPFPHEDILV 885
LQRP+ + + A P GT A P P+G + P
Sbjct: 234 LQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAA 293
Query: 886 ASIVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAP-AVAAAITQEG 944
++ L + + SA ++ P + P ++ +++P AP + +A + +
Sbjct: 294 PALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQT 353
Query: 945 MSAVAGFSPEWAALAITVPITEEDGT--PEGPVTPATTVHAPEEPDTAAVRV--STPEEP 1000
+ + P A ++ P + + P P++P T P+ P A+ + P P
Sbjct: 354 LPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATP-PPQAPPALALPPLQAPPSPP 412
Query: 1001 ASPAA---AVPTPEEPTS--------PAAAVPTP--EEPTSPAAAVP------PPEEPTS 1041
ASP A P+P+ P + P + P+P + P SP A+ P PP +
Sbjct: 413 ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 472
Query: 1042 PAAAVPTPEEPTSPAA------AVPTPEEPTSPAA-----AVPTPEEPTSPAAAVPTPEE 1090
AA P P+ PA+ A P P+ P AA A P P+ P PA A P +
Sbjct: 473 SLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAP--PALATPPLQA 530
Query: 1091 PTSPAAAVPTPEEPTSPAAAVP-----TPEEPASPAAAVPTPEEPASPAAAVPTPEEPAF 1145
SP A+ P + P SP+A++P TP A P A P + P SP A+ PT + P
Sbjct: 531 LPSPPASFP-GQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPAS-PTLQAPR- 587
Query: 1146 PAPAVPTPEESAS------AAVAVPTPEESASPAAAVPTPAESASFAAVVATLEE----- 1194
P P P+ S S A P P S SP++ + P + ++ +T EE
Sbjct: 588 -RPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYD 646
Query: 1195 --PTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTS-PAAAVPTL 1251
P AA+ P P A +A PAA S PA A P P P A P
Sbjct: 647 SGPEGGAAASPPPDAELAACH----PAA---WSRGPAPPLAFRGAPGAPLPWPPATGP-- 697
Query: 1252 EEPTSSAAAVLTPEELSSPAASVPTP---EEPASPAAAVSNLEEPASPAAAVPTPEVAAI 1308
SA + T E P ++ P P + SP + A A+ +P+ A +
Sbjct: 698 ----GSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARL 753
Score = 94.4 bits (233), Expect = 7e-19
Identities = 101/392 (25%), Positives = 154/392 (39%), Gaps = 42/392 (10%)
Query: 983 APEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAA-----VPTPEEPTSPAAAVPPPE 1037
A E P +A+ + + P P+P AA +P P P P
Sbjct: 147 ATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPR 206
Query: 1038 EPTSPAA----AVPTPEEPTSPAAA--VPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEP 1091
+ S A+ P+P P+A + P + ++A P S +A TP P
Sbjct: 207 KSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAP 266
Query: 1092 TSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAV--PTPEEPASPAAAVPTPEEPAFPAPA 1149
P+ P + P P P + A+PA +P SP+AA+ + P PA
Sbjct: 267 AHPSQPKPKGLQALRPPQVTP-PRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPA-- 323
Query: 1150 VPTPEESA-SAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAM 1208
TP S+ + +A P P A P+P+ S + + P S A + +
Sbjct: 324 --TPHSSSLTCQLATPLP-------LAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTL 374
Query: 1209 VATLEEFTSPAASVPTSEEPASLAAAVSNP--EEPTSPAAAVPT--LEEPTSSAAAVLTP 1264
AT SP S P + P A++ P + P SP A+ P L P+ A L
Sbjct: 375 QATHSFLPSPPLS-PLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAV 433
Query: 1265 EELSSPAASVPTP--EEPASPAAAVSNLEEPASPAAAVPT---PEVAAIPAASVPTPEV- 1318
L +P + P+P + P SP A+ P SP+A P+ P +AA P P+P
Sbjct: 434 HLLQAPFSPPPSPPVQAPFSPPAS-----PPVSPSATPPSQAPPSLAAPPLQVPPSPPAS 488
Query: 1319 PAIPAAAVPPMEEVSPIGVPFLGVSAHTDSVP 1350
P + +A PP + P+ P L ++ P
Sbjct: 489 PPMSPSATPPPQAPPPLAAPPLQLAKPPPQAP 520
Score = 86.3 bits (212), Expect = 2e-16
Identities = 107/387 (27%), Positives = 150/387 (38%), Gaps = 40/387 (10%)
Query: 1000 PASPAAAVPTPEEPTSPAAAVP-TPEEPTSPAAAVPPPEEPTSP-AAAVPTPEEPTSPAA 1057
PA+ A + TP P SP P TP AA +P + A + P S
Sbjct: 17 PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76
Query: 1058 AVPTPEEPTS---PAAAVPTPEE-PTSPAAAVPTPEEPTSPAAAVPTPEE-PTSPAAAVP 1112
A PT TS PA+ P +P A +P +SP A T P
Sbjct: 77 AGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRI 136
Query: 1113 TPEEPASPAAAVPTPEEPASPAAAV--PTPEEPAFPAPAVPTPEESASAAVAVPTPEESA 1170
+ EE + A P+ A A A + P P+PA+ +A V +P P SA
Sbjct: 137 SAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSA 196
Query: 1171 SPAAAVPTPAESASFAAVVATLEEPTSPAA----------SVPTPAAMVATLEEFTSPAA 1220
P P +S S A+ +T E SPAA P ++ ++ +SPA
Sbjct: 197 RPRPPTEGPRKSVSSASEHSTTEP--SPAARRRPSAGGGLQRPASRSLSSSATPLSSPAR 254
Query: 1221 SVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEP 1280
S P++ A S P+ A P + P AA L P LSS + P
Sbjct: 255 SGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP--LSSSPLATP----- 307
Query: 1281 ASPAAAVSNLEEPASPA--------AAVPTPEVAAIPAASVPTPEVPAIPA-AAVPPMEE 1331
SP+AA+ + P PA + TP A P+ S P P + +P+ A PP +
Sbjct: 308 -SPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAP-PSLQTLPSPPATPPSQA 365
Query: 1332 VSPIGVPFL-GVSAHTDSVPISEEGTP 1357
+ +G P L + S P+S TP
Sbjct: 366 TTSLGSPTLQATHSFLPSPPLSPLATP 392
Score = 80.1 bits (196), Expect = 1e-14
Identities = 115/497 (23%), Positives = 167/497 (33%), Gaps = 79/497 (15%)
Query: 892 EEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGF 951
+ + A A + A P + P G SP P AA+ G + G
Sbjct: 4 KRDKAKAGAAARTPAARAPGLLTPRPPG--------SPRPPPPVTPAALRVLGAAGAVGR 55
Query: 952 SPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPE 1011
P + E G G P + A P A ++ P
Sbjct: 56 KP----------LAERAGGIGGATIPESAPRAG------------PTRSAGTSSRNPASR 93
Query: 1012 EPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAA 1071
P S P + TSP P A+ T P + EE + A
Sbjct: 94 PPASGRGERAPPAKNTSPGPVSSPGR------ASGTTRPGPLGQKGLRISAEETVARGKA 147
Query: 1072 VPTPEEPTSPAAAVPTPEEPT--SPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEE 1129
P+ A A PT +P+ A+ +P P A P P +
Sbjct: 148 TEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRK 207
Query: 1130 PASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVV 1189
S A+ T E P+PA SA + P +S A + +PA S A
Sbjct: 208 SVSSASEHSTTE----PSPAARR-RPSAGGGLQRPASRSLSSSATPLSSPARSGPSAR-- 260
Query: 1190 ATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVP 1249
T P P S P P L+ P + P + +L S+P SP+AA+
Sbjct: 261 GTPRAPAHP--SQPKPKG----LQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQ 314
Query: 1250 TLEEPT--------SSAAAVLTPEELSSPAASVPT-----PEEPASPAA-AVSNLEEP-- 1293
+ PT S + TP L+ P+ S P P PA+P + A ++L P
Sbjct: 315 SQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTL 374
Query: 1294 --------ASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVP--PMEEVSPIGVPFLGVS 1343
+ P + + TP A PA ++P + P P A+ P P+ SP L V
Sbjct: 375 QATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAV- 433
Query: 1344 AHTDSVPISEEGTPVLE 1360
H P S +P ++
Sbjct: 434 -HLLQAPFSPPPSPPVQ 449
Score = 31.2 bits (69), Expect = 7.5
Identities = 48/191 (25%), Positives = 65/191 (34%), Gaps = 24/191 (12%)
Query: 829 PVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASI 888
P+LQ P A PT++ P P+ S G + AL P P +
Sbjct: 569 PLLQVPPSPPASPTLQAPRRPPTPGPDTSVS--------GPRLTLALAPGPPPPPSRSPS 620
Query: 889 VSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAV 948
+L D+ + SA S PEG A AA P+ A A G +
Sbjct: 621 STLSGPDLAGHSSSATSTPEELRGYDSGPEGGA--AASPPPDAELAACHPAAWSRGPAPP 678
Query: 949 AGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVP 1008
F A P+ T G T++ E P++A TP +P A P
Sbjct: 679 LAFRG-----APGAPLPWPPATGPGSADGLCTIYETEGPESA-----TP----APGALDP 724
Query: 1009 TPEEPTSPAAA 1019
P TS A
Sbjct: 725 GPSPGTSGGKA 735
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 120 bits (300), Expect = 1e-26
Identities = 177/612 (28%), Positives = 226/612 (36%), Gaps = 112/612 (18%)
Query: 812 KQVTKAG-NTEPVLE----EWIPVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAP 866
K + KAG EP LE E +P+L P + P P E TS P P
Sbjct: 417 KPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSP----------PPEESPTS----PPP 462
Query: 867 EGTAVVAALVPFPHEDILVASIVS--LEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVA 924
E + + P + A +S LEE ++ PE + + S P +
Sbjct: 463 EASRLSPPPEELPASPLPEALHLSRPLEESPLSPP----PEESPLSPPPESSPFSPLEES 518
Query: 925 AVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTP------------E 972
+S PEE+ P+ A + SP + ++ P E +P E
Sbjct: 519 PLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEE 578
Query: 973 GPVTPATTVHAPEEPDTAAVRVSTP--EEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPA 1030
P++P +P P A R+ P E P SP P E P SP P +
Sbjct: 579 SPMSPPPE-ESPMSPPPEASRLFPPFEESPLSP----PPEESPLSPPPEASRLSPPPEDS 633
Query: 1031 AAVPPPEE-PTSPAAAVPTPEEPTSPAAAVPTPEE-PTSPAAAVPTPEEPTSP----AAA 1084
PPPEE P SP V + P PEE P SP P E PTSP +
Sbjct: 634 PMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSP----PPEESPTSPPPEASRL 689
Query: 1085 VPTPEE-PTSP----AAAVPTPEE-----PTSPAAAVPTPEEP-----ASPAAAVPTPEE 1129
P PE+ PTSP + A P PE+ P + +P PEEP + P PEE
Sbjct: 690 SPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEE 749
Query: 1130 PASPAAAVPTPEEPAFPAPA-----VPTPEESASAAVAVPTPEE-SASPAAAVPTPAESA 1183
P P PEEP A P PEE AV PEE SP A P +
Sbjct: 750 P----HLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAV----PEEPHLSPQAEGPHLSPQP 801
Query: 1184 SFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEP-T 1242
+ EEP + VP + EE + P SEEP PEE
Sbjct: 802 EELHLSPQTEEP--HLSPVPEEPCLSPQPEE----SHLSPQSEEP----CLSPRPEESHL 851
Query: 1243 SPAAAVPTL----EEPTSSAAAVLTPEELS----------SPAASVPTPEEPASPAAAVS 1288
SP P L E+P PEEL SP P EP P +
Sbjct: 852 SPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPL 911
Query: 1289 NLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPMEEVSPIGVPFLGVSAHTDS 1348
E P SP+ P+ +P +P P P I AAA P + + + PF A DS
Sbjct: 912 PEELPLSPSGE-PSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPF---GAKGDS 967
Query: 1349 VPISEEGTPVLE 1360
P S P+LE
Sbjct: 968 DPESPLAAPILE 979
Score = 95.9 bits (237), Expect = 2e-19
Identities = 141/489 (28%), Positives = 184/489 (37%), Gaps = 120/489 (24%)
Query: 953 PEWAALAITVPITEEDGTP--EGPVTPATTVHAPEEPDTAAVRVSTPEE--PASP----A 1004
PE + L+ +P+ P E P++P +P P A R+S P E P SP +
Sbjct: 648 PEVSRLS-PLPVVSRLSPPPEESPLSPPPE-ESPTSPPPEASRLSPPPEDSPTSPPPEDS 705
Query: 1005 AAVPTPEE-----PTSPAAAVPTPEEP-----TSPAAAVPPPEEPTSPAAAVPTPEEP-T 1053
A P PE+ P + +P PEEP + P PEEP P PEEP
Sbjct: 706 PASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLS----PRPEEPHL 761
Query: 1054 SPAAAVP-------------TPEEP-TSPAAA----VPTPEE-----PTSPAAAVPTPEE 1090
SP A P PEEP SP A P PEE T P PEE
Sbjct: 762 SPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEE 821
Query: 1091 PT----------SPAAAVP-----------TPEEPTSPAAAVPTPEEPASPAAAVPTPEE 1129
P SP + P +PE P + P PE+P P PEE
Sbjct: 822 PCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLS--PRPEKPPEEPGQCPAPEE 879
Query: 1130 ------PASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESA 1183
P P+ + P EPA P P P+ E S SP P P
Sbjct: 880 LPLFPPPGEPSLS-PLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDP---- 934
Query: 1184 SFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTS 1243
L P SP + P A+ + L E P A S+PE P
Sbjct: 935 --------LPPPLSPIITAAAPPAL-SPLGELEYPFG-----------AKGDSDPESP-- 972
Query: 1244 PAAAVPTLEEPTS-SAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPT 1302
A P LE P S A T E P P+P P PA+ + L EP P + P
Sbjct: 973 --LAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPI--LMEPLPPQCS-PL 1027
Query: 1303 PEVAAIPAASVPTP-EVPAIPAAAVPPMEEVSPIGVPFLGVSAHT-----DSVPISEEGT 1356
+ + +P S P+ PA+P + P+ SPIG +GVS ++ +SE
Sbjct: 1028 LQHSLVPQNSPPSQCSPPALPLSVPSPL---SPIG-KVVGVSDEAELHEMETEKVSEPEC 1083
Query: 1357 PVLEEASST 1365
P LE ++++
Sbjct: 1084 PALEPSATS 1092
Score = 92.4 bits (228), Expect = 3e-18
Identities = 115/394 (29%), Positives = 141/394 (35%), Gaps = 65/394 (16%)
Query: 963 PITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEP------TSP 1016
P+ PE TP +EPD A+ V+ +P P+EP P
Sbjct: 367 PVCSRFSPPEPGDTPT------DEPD--ALYVACQGQPKGGHVTSMQPKEPGPLQCEAKP 418
Query: 1017 AAAVPTPEEPTSPAAA------VPPPEE-PTSPAAAVPTPEEPTSPAAAV----PTPEE- 1064
EP A +PPPEE P SP P E PTSP P PEE
Sbjct: 419 LGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSP----PPEESPTSPPPEASRLSPPPEEL 474
Query: 1065 PTSPAAAV-----PTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPAS 1119
P SP P E P SP P E P SP +P P + P E P S
Sbjct: 475 PASPLPEALHLSRPLEESPLSP----PPEESPLSPPPE-SSPFSPLEESPLSPPEESPPS 529
Query: 1120 PAAAVPTPEEPASPAAAVPTPEEPAFPAP-AVPTPEESASAAVAVPTPEESASP----AA 1174
PA P P + + P E P P P +PT ++ ++ P E SP +
Sbjct: 530 PALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESP 589
Query: 1175 AVPTPAESASFAAV-VATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAA 1233
P P S F + L P + P P A + SP S P E P S
Sbjct: 590 MSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSP-MSPPPEESPMSPPP 648
Query: 1234 AVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEP 1293
VS SP V L P PEE SP S P E P SP S L P
Sbjct: 649 EVSR----LSPLPVVSRLSPP---------PEE--SP-LSPPPEESPTSPPPEASRLSPP 692
Query: 1294 ASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVP 1327
+ P PE + PA+ P + ++P P
Sbjct: 693 PEDSPTSPPPEDS--PASPPPEDSLMSLPLEESP 724
Score = 74.7 bits (182), Expect = 6e-13
Identities = 103/405 (25%), Positives = 149/405 (36%), Gaps = 66/405 (16%)
Query: 962 VPITEEDGTPE-GPVTPATTVHAPEEPDTAAVRVSTPEE-PASPAAAVPTPEEPTSPAAA 1019
+P+ G P P+ + P EP + + PEE P SP+ P+ P
Sbjct: 880 LPLFPPPGEPSLSPLLGEPALSEPGEPPLSPL----PEELPLSPSGE-PSLSPQLMPPDP 934
Query: 1020 VPTPEEPTSPAAAVPP---------------PEEPTSPAAAVPTPEEPTSPAA-AVPTPE 1063
+P P P AAA P +P SP AA P E P SP A T
Sbjct: 935 LPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAA-PILETPISPPPEANCTDP 993
Query: 1064 EPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAA 1123
EP P P+P P PA+ P EP P + P + P + P+ P + +
Sbjct: 994 EPVPPMILPPSPGSPVGPAS--PILMEPLPPQCS-PLLQHSLVPQNSPPSQCSPPALPLS 1050
Query: 1124 VPTPEEP------ASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVP 1177
VP+P P S A + E P P E SA++ +P+P S A P
Sbjct: 1051 VPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATS--PLPSPMGDLSCPAPSP 1108
Query: 1178 TPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVS- 1236
PA + L E T+P L+ +P + + P SLA+ +
Sbjct: 1109 APALDD-----FSGLGEDTAP-------------LDGIDAPGSQPEPGQTPGSLASELKG 1150
Query: 1237 -----NPEE--PTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSN 1289
+PEE P +P P ++ + EE +P A P + +SN
Sbjct: 1151 SPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPPTLIKSDIVNEISN 1210
Query: 1290 LEEPASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPMEEVSP 1334
L + +A+ P E P P PE + + +VSP
Sbjct: 1211 LSQ-GDASASFPGSE----PLLGSPDPEGGGSLSMELGVSTDVSP 1250
Score = 60.1 bits (144), Expect = 1e-08
Identities = 123/526 (23%), Positives = 181/526 (34%), Gaps = 92/526 (17%)
Query: 910 PAVTVSVPEGTAAVAAVSSPEETAPAV--AAAITQEGMSAVA-GFSPEWAALAITVPITE 966
PA+ + +P A+ S P AP + + T G+S A GF A +VP +
Sbjct: 2100 PALHLRIPPQPGALG--SPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAG---SVPGPD 2154
Query: 967 EDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAA--AVPTPEEPTSPAAAVPTPE 1024
G + P P + D + + P EP P A P PT A P
Sbjct: 2155 SPGELFLKLPPQVPAQVPSQ-DPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLG 2213
Query: 1025 EPTSPAAAVP----------PPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPT 1074
+ P A P P +P++P + P P+ AVP A+ P
Sbjct: 2214 ASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLK-PRCPSLDNLAVPESPGVGGGKASEPL 2272
Query: 1075 PEEP------------------TSPAAAVPTPEEPTSPAAA-------VPTPEEPTSPAA 1109
P +SP+ P SP++ + TP+ +P
Sbjct: 2273 LSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLT 2332
Query: 1110 AVPTPEEPASPAAAVPTPEEPASPAAAVPTP-----------------EEPAFPAPAVPT 1152
+ EP SP + P+EP A P+P + P P P P
Sbjct: 2333 PRASQVEPQSPGLGL-RPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPP 2391
Query: 1153 PEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATL 1212
PE + A+P + P + VP +S S + T P S A P+P
Sbjct: 2392 PE----SCCALPPRSLPSDPFSRVPASPQSQSSSQSPLT-PRPLSAEAFCPSPVTPRFQS 2446
Query: 1213 EEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEEL-SSPA 1271
+ S S P S +P A + P P P A +S A P L + PA
Sbjct: 2447 PDPYSRPPSRPQSRDP---FAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPA 2503
Query: 1272 ----ASVPTPEEPASPAAAVSNLEEPASPA-AAVPTPEVAAIPAASVPTPEVPAIPAAAV 1326
A VP+ + P + + P + A P+P P A P +P +
Sbjct: 2504 GELHAKVPSGQPP-------NFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGL 2556
Query: 1327 PPMEEV-SPIGV-PFLGVSAHTDSVPIS----EEGTPVLEEASSTG 1366
PP + S G P LG T+ + G+P+ + STG
Sbjct: 2557 PPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTG 2602
Score = 53.9 bits (128), Expect = 1e-06
Identities = 76/275 (27%), Positives = 101/275 (36%), Gaps = 39/275 (14%)
Query: 1077 EPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEP------ 1130
E +P + +P EP PT E A V +P P+EP
Sbjct: 363 EQHTPVCSRFSPPEPGD----TPTDEPD---ALYVACQGQPKGGHVTSMQPKEPGPLQCE 415
Query: 1131 ASPAAAVPTPEEPAFPAPA------VPTPEESASAAVAVPTPEESASPAAAVPTPAESAS 1184
A P EP AP +P PEES + P PEES + P E++
Sbjct: 416 AKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLS----PPPEESPTSP-----PPEASR 466
Query: 1185 FAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSP 1244
+ L PA+ +P + LEE SP S P E P S S+P P
Sbjct: 467 LSPPPEEL-----PASPLPEALHLSRPLEE--SPL-SPPPEESPLS-PPPESSPFSPLEE 517
Query: 1245 AAAVPTLEEPTSSAAAV-LTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTP 1303
+ P E P S A L+P +SP S P E P SP P + P P
Sbjct: 518 SPLSPPEESPPSPALETPLSPPPEASPL-SPPFEESPLSPPPEELPTSPPPEASRLSPPP 576
Query: 1304 EVAAIPAASVPTPEVPAIPAAAVPPMEEVSPIGVP 1338
E + + +P P A+ + P E SP+ P
Sbjct: 577 EESPMSPPPEESPMSPPPEASRLFPPFEESPLSPP 611
Score = 48.5 bits (114), Expect = 5e-05
Identities = 81/373 (21%), Positives = 120/373 (32%), Gaps = 58/373 (15%)
Query: 966 EEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEE 1025
+ + + P+TP P R +P+ P S + P +P +P P P+
Sbjct: 2416 QSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPD-PYSRPPSRPQSRDPFAPLHKPPRPQP 2474
Query: 1026 P-----------TSPAAAVPPPEEPTSPA----AAVPTPEEP-------TSPAAAVPTPE 1063
P TS A P P PA A VP+ + P T P+P
Sbjct: 2475 PEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPM 2534
Query: 1064 EPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPT--------PE 1115
T P A +P P +P P S PT +P S V T P
Sbjct: 2535 RFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPL 2594
Query: 1116 EPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEE------- 1168
P+S + P P + +P P P ++P AS + +P E
Sbjct: 2595 GPSSGSTGESYGLSPLRPPSVLPPPA----PDGSLPYLSHGASQRSGITSPVEKREDPGT 2650
Query: 1169 ---SASPAAAVPTPAESASFAAVVATLEEPTS----PAASVPTPAAMVATLEEFTSPAAS 1221
S+ A +P + LE+ + +E + AA+
Sbjct: 2651 GMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAA 2710
Query: 1222 VPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSP---AASVPT-- 1276
P S A S+P P S+ L P +LS P S P+
Sbjct: 2711 AGAVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDD 2770
Query: 1277 ----PEEPASPAA 1285
P PA+P++
Sbjct: 2771 RLSRPPPPATPSS 2783
Score = 45.4 bits (106), Expect = 4e-04
Identities = 82/370 (22%), Positives = 122/370 (32%), Gaps = 60/370 (16%)
Query: 963 PITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEE---------P 1013
P + D + P+TP PE R S P +P S A P + P
Sbjct: 2371 PGSYTDPYAQPPLTPRPQPPPPESCCALPPR-SLPSDPFSRVPASPQSQSSSQSPLTPRP 2429
Query: 1014 TSPAAAVPTPEEPT--SPAAAVPPPEEPTS--PAAAVPTPEEPTSPAAAVPTPEE----- 1064
S A P+P P SP PP P S P A + P P P A
Sbjct: 2430 LSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSL 2489
Query: 1065 ---------PTSPA----AAVPTPEEP-------TSPAAAVPTPEEPTSPAAAVPTPEEP 1104
P PA A VP+ + P T P+P T P A +P
Sbjct: 2490 GAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKP 2549
Query: 1105 TSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVP----TPEESASAA 1160
P +P P S PT +P S V T +P P T E +
Sbjct: 2550 PVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSP 2609
Query: 1161 VAVPTPEESASPAAAVPTPAESAS-FAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPA 1219
+ P+ +P ++P + AS + + + +E+ P + + A
Sbjct: 2610 LRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLA-----------T 2658
Query: 1220 ASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTP-- 1277
A +P +++P + + E+ L + +E ++ AA P
Sbjct: 2659 AELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPG 2718
Query: 1278 ---EEPASPA 1284
EP+SPA
Sbjct: 2719 SWGAEPSSPA 2728
Score = 43.5 bits (101), Expect = 0.001
Identities = 34/100 (34%), Positives = 40/100 (40%), Gaps = 7/100 (7%)
Query: 1008 PTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTS 1067
P PE PT + +A PPPEEP+ P + P P SP P E PT
Sbjct: 4884 PAPEPPTQHSYTYNVSNLDVRQLSA-PPPEEPSPPPS--PLAPSPASPPTE-PLVELPTE 4939
Query: 1068 PAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSP 1107
P A P P P A+ P P P A P E + P
Sbjct: 4940 PLAEPPVPS--PLPLASSPESARP-KPRARPPEEGEDSRP 4976
Score = 41.2 bits (95), Expect = 0.007
Identities = 33/96 (34%), Positives = 38/96 (39%), Gaps = 9/96 (9%)
Query: 1060 PTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPAS 1119
P PE PT + +A P PEEP+ P + P P SP P E P
Sbjct: 4884 PAPEPPTQHSYTYNVSNLDVRQLSA-PPPEEPSPPPS--PLAPSPASPPTE-PLVELPTE 4939
Query: 1120 PAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEE 1155
P A P P SP +PE A P P PEE
Sbjct: 4940 PLAEPPVP----SPLPLASSPES-ARPKPRARPPEE 4970
Score = 40.8 bits (94), Expect = 0.009
Identities = 34/102 (33%), Positives = 44/102 (43%), Gaps = 17/102 (16%)
Query: 1008 PTPEE-PTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPT 1066
P P+ P A P P+ P P PP T P P PT P ++ P+ P+
Sbjct: 4267 PGPQTGPLQELGAGPRPQGP--PRLPAPPGALSTGPVLG---PVHPTPPPSSPQEPKRPS 4321
Query: 1067 ---SPAAAVPT-----PEEPTSPAAAVPTPEEP---TSPAAA 1097
SP++ +PT P P +P PT E P SPAAA
Sbjct: 4322 QLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAA 4363
Score = 40.8 bits (94), Expect = 0.009
Identities = 33/96 (34%), Positives = 38/96 (39%), Gaps = 9/96 (9%)
Query: 1047 PTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTS 1106
P PE PT + +A P PEEP+ P + P P SP P E PT
Sbjct: 4884 PAPEPPTQHSYTYNVSNLDVRQLSA-PPPEEPSPPPS--PLAPSPASPPTE-PLVELPTE 4939
Query: 1107 PAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEE 1142
P A P P SP +PE A P PEE
Sbjct: 4940 PLAEPPVP----SPLPLASSPES-ARPKPRARPPEE 4970
Score = 40.0 bits (92), Expect = 0.016
Identities = 32/95 (33%), Positives = 38/95 (40%), Gaps = 20/95 (21%)
Query: 1086 PTPEEPTSPA------------AAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASP 1133
P PE PT + + P PEEP+ P + P PASP P E P P
Sbjct: 4884 PAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPS--PLAPSPASPPTE-PLVELPTEP 4940
Query: 1134 AAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEE 1168
A P P P P +PE + A P PEE
Sbjct: 4941 LAEPPVPS----PLPLASSPESARPKPRARP-PEE 4970
Score = 39.3 bits (90), Expect = 0.027
Identities = 82/369 (22%), Positives = 126/369 (34%), Gaps = 52/369 (14%)
Query: 1004 AAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVP--TPEEPTSPAAAVPT 1061
+ A+PT + S P +P +++PP P+ V TP E
Sbjct: 4597 SGALPTGPDYYSQLLTKNNLSNPPTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAA 4656
Query: 1062 PEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPA 1121
+ A + + AA+PTP + + + E+ SP + VP AS
Sbjct: 4657 SARDSERALRDTSEVKSLDLLAALPTPPHNQTEDVRMESDEDSDSPDSIVP-----ASSP 4711
Query: 1122 AAVPTPEEPASPAAA---------VPTPEEPAFPAPAVPT-PEESASAAVAVPTPEESAS 1171
++ E P P +P P P ++P P+ A+ + P +
Sbjct: 4712 ESILGEEAPRFPHLGSGRWEQEDRALSPVIPLIPRASIPVFPDTKPYGALGLEVPGK--- 4768
Query: 1172 PAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEE---P 1228
S +V+ T+ S AA+ MVA E + +P S E P
Sbjct: 4769 -LPVTTWEKGKGSEVSVMLTV----SAAAAKNLNGVMVAVAELLSM---KIPNSYEVLFP 4820
Query: 1229 ASLAAAVSNPE--EPTSPAAAVPTLEEPTSSAA--------AVLTPEELSSPAASV---- 1274
S A A + P+ E P LE + AVL L S +
Sbjct: 4821 ESPARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQLDILSLLK 4880
Query: 1275 ---PTPEEPASPAAA--VSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPM 1329
P PE P + VSNL+ +A P E + P+ P+P P P
Sbjct: 4881 QESPAPEPPTQHSYTYNVSNLD--VRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPT 4938
Query: 1330 EEVSPIGVP 1338
E ++ VP
Sbjct: 4939 EPLAEPPVP 4947
Score = 38.5 bits (88), Expect = 0.047
Identities = 28/95 (29%), Positives = 36/95 (37%), Gaps = 20/95 (21%)
Query: 1099 PTPEEPTSPA------------AAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFP 1146
P PE PT + + P PEEP+ P + P PASP P EP
Sbjct: 4884 PAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPS--PLAPSPASP------PTEPLVE 4935
Query: 1147 APAVPTPEESASAAVAVPTPEESASPAAAVPTPAE 1181
P P E + + + + ESA P P E
Sbjct: 4936 LPTEPLAEPPVPSPLPLASSPESARPKPRARPPEE 4970
Score = 38.1 bits (87), Expect = 0.061
Identities = 32/105 (30%), Positives = 41/105 (39%), Gaps = 7/105 (6%)
Query: 964 ITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTP 1023
+ +E PE P + T + D + PEEP+ P + P P SP P
Sbjct: 4879 LKQESPAPEPPTQHSYTYNV-SNLDVRQLSAPPPEEPSPPPS--PLAPSPASPPTE-PLV 4934
Query: 1024 EEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSP 1068
E PT P A PP P A+ P P P A P E + P
Sbjct: 4935 ELPTEPLA--EPPVPSPLPLASSPESARP-KPRARPPEEGEDSRP 4976
Score = 37.0 bits (84), Expect = 0.14
Identities = 32/119 (26%), Positives = 46/119 (38%), Gaps = 14/119 (11%)
Query: 1034 PPPEEPTSPAAAVPTPEEPTSPAAAVPTPEE-PTSPAAAVPTPEEPTSPAAAVPTPEEPT 1092
PP +EP + + + P P+ P A P P+ P P P T
Sbjct: 4241 PPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGP--PRLPAPPGALST 4298
Query: 1093 SPAAAVPTPEEPTSPAAAVPTPEEPA---SPAAAVPT-----PEEPASPAAAVPTPEEP 1143
P P PT P ++ P+ P+ SP++ +PT P P +P PT E P
Sbjct: 4299 GPVLG---PVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPP 4354
Score = 37.0 bits (84), Expect = 0.14
Identities = 31/99 (31%), Positives = 41/99 (41%), Gaps = 16/99 (16%)
Query: 949 AGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVP 1008
AG P+ P G GPV P +P+EP P + SP++ +P
Sbjct: 4279 AGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEP-------KRPSQLPSPSSQLP 4331
Query: 1009 TPEE--PTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAA 1045
T + PT P P P+ PT + PP SPAAA
Sbjct: 4332 TEAQLPPTHP--GTPKPQGPT-----LEPPPGRVSPAAA 4363
Score = 36.6 bits (83), Expect = 0.18
Identities = 30/91 (32%), Positives = 41/91 (45%), Gaps = 19/91 (20%)
Query: 1000 PASPAAAVPTPEEPT---SPAAAVPT-----PEEPTSPAAAVPPPEEPT---SPAAAVPT 1048
P A P P+ P +P A+ T P PT P ++ P+ P+ SP++ +PT
Sbjct: 4273 PLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPT 4332
Query: 1049 -----PEEPTSPAAAVPTPEEP---TSPAAA 1071
P P +P PT E P SPAAA
Sbjct: 4333 EAQLPPTHPGTPKPQGPTLEPPPGRVSPAAA 4363
Score = 36.2 bits (82), Expect = 0.23
Identities = 67/320 (20%), Positives = 108/320 (33%), Gaps = 44/320 (13%)
Query: 991 AVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPE 1050
A+R ++ + AA+PTP + + + E+ SP + V P S ++ E
Sbjct: 4664 ALRDTSEVKSLDLLAALPTPPHNQTEDVRMESDEDSDSPDSIV-----PASSPESILGEE 4718
Query: 1051 EPTSPAAA---------VPTPEEPTSPAAAVPT-PEEPTSPAAAVPTPEEPTSPAAAVPT 1100
P P +P P P A++P P+ A + P + V T
Sbjct: 4719 APRFPHLGSGRWEQEDRALSPVIPLIPRASIPVFPDTKPYGALGLEVPGK-----LPVTT 4773
Query: 1101 PEEPTSPAAAVPTPEEPASP--------------AAAVPTPEEPASPAAAVPTPEEPAFP 1146
E+ +V A+ + +P E P + EP
Sbjct: 4774 WEKGKGSEVSVMLTVSAAAAKNLNGVMVAVAELLSMKIPNSYEVLFPESPARAGTEPKKG 4833
Query: 1147 APAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPA 1206
P +E + T + AV P + + +L + SPA PT
Sbjct: 4834 EAEGPGGKEKGLEGKSPDTGPDWLKQFDAV-LPGYTLKSQLDILSLLKQESPAPEPPTQH 4892
Query: 1207 AMVATLEEFTSPAASVPTSEE----PASLAAAVSNPEEPTSPAAAVPT---LEEPTSSAA 1259
+ + S P EE P+ LA + ++P PT P +PT E P S
Sbjct: 4893 SYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASP--PTEPLVELPTEPLAEPPVPSPL 4950
Query: 1260 AVLTPEELSSPAASVPTPEE 1279
+ + E + P PEE
Sbjct: 4951 PLASSPESARPKPRARPPEE 4970
Score = 34.7 bits (78), Expect = 0.67
Identities = 29/107 (27%), Positives = 36/107 (33%), Gaps = 13/107 (12%)
Query: 1138 PTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTS 1197
P PE P + A P E S P+ P+PA + V E PT
Sbjct: 4884 PAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLV----ELPTE 4939
Query: 1198 PAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSP 1244
P A P P+ + P AS P S P A E+ P
Sbjct: 4940 PLAEPPVPSPL---------PLASSPESARPKPRARPPEEGEDSRPP 4977
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
Length = 816
Score = 115 bits (289), Expect = 2e-25
Identities = 141/516 (27%), Positives = 191/516 (37%), Gaps = 67/516 (12%)
Query: 834 PSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEE 893
P+RT+ P A P + TS V +P + P + + + S EE
Sbjct: 79 PTRTSRPPASGRGERAP---PAKNTSPGPVSSPGRASGTTRPGPLGQKGLRI----SAEE 131
Query: 894 EDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSP 953
A AP+R+ + A A S P P+ A A G P
Sbjct: 132 TVARGKATEAPKRSALSA---------GARRDTSGPTPGTPSPAMARRSRAAGTEVGL-P 181
Query: 954 EWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVR-------VSTPEEPASPAAA 1006
A A P TE P V+ A+ H+ EP AA R + P + ++A
Sbjct: 182 RPAPSARPRPPTEG---PRKSVSSASE-HSTTEPSPAARRRPSAGGGLQRPASRSLSSSA 237
Query: 1007 VPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPT 1066
P S +A TP P P+ P + P P P + +PA P P
Sbjct: 238 TPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTP-PRKDAAPALG-PLSSSPL 295
Query: 1067 SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPT 1126
A P+P P SP+A P+ PA T P+ A + P A
Sbjct: 296 ----ATPSPSAPPSPSAPPSLQTLPSPPA---------TPPSQATTSLGSPTLQATHSFL 342
Query: 1127 PEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFA 1186
P P SP A P PA P + P P+P S P + + TP+ A A
Sbjct: 343 PSPPLSPLATPPPQAPPALALPPLQAP----------PSPPASP-PLSPLATPSPQAPNA 391
Query: 1187 AVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAV-----SNPEEP 1241
V L+ P SP S P A SP+A+ P S+ P SLAA S P P
Sbjct: 392 LAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSAT-PPSQAPPSLAAPPLQVPPSPPASP 450
Query: 1242 TSPAAAVPTLEEPTSSAAAVLT---PEELSSPAASVPTPEEPASPAAAVSNLEEPASPAA 1298
+A P + P AA L P + PA + P + SP A+ + P SP+A
Sbjct: 451 PMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPG-QAPFSPSA 509
Query: 1299 AVPTPEVAAIPAASVPTPEVPAIPAAAVPPMEEVSP 1334
++P +A P + P V A P VPP SP
Sbjct: 510 SLPMSPLATPPPQA---PPVLAAPLLQVPPSPPASP 542
Score = 105 bits (262), Expect = 3e-22
Identities = 140/521 (26%), Positives = 202/521 (38%), Gaps = 74/521 (14%)
Query: 831 LQRPSRTAAVPTVKDALDAALPSPE-EGTSIAAV----PAPEGTAVVAALVPFPHEDILV 885
LQRP+ + + A P GT A P P+G + P
Sbjct: 225 LQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAA 284
Query: 886 ASIVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTA-----AVAAVSSPEETAPAVAAAI 940
++ L + + SAP + P ++P A A ++ SP T A + +
Sbjct: 285 PALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSP--TLQATHSFL 342
Query: 941 TQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEP 1000
+S +A P+ P+ P P +P+ P+ AV + + P
Sbjct: 343 PSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLL--QAP 400
Query: 1001 ASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAA--- 1057
SP + P + P SP A+ P SP+A PP + P S AA P P+ PA+
Sbjct: 401 FSPPPSPPV-QAPFSPPAS-----PPVSPSAT-PPSQAPPS-LAAPPLQVPPSPPASPPM 452
Query: 1058 ---AVPTPEEPTSPAA-----AVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAA 1109
A P P+ P AA A P P+ P PA A P + SP A+ P + P SP+A
Sbjct: 453 SPSATPPPQAPPPLAAPPLQLAKPPPQAP--PALATPPLQALPSPPASFP-GQAPFSPSA 509
Query: 1110 AVP-----TPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESAS------ 1158
++P TP A P A P + P SP A+ PT + P P P P+ S S
Sbjct: 510 SLPMSPLATPPPQAPPVLAAPLLQVPPSPPAS-PTLQAPR--RPPTPGPDTSVSGPRLTL 566
Query: 1159 AAVAVPTPEESASPAAAVPTPAESASFAAVVATLEE-------PTSPAASVPTPAAMVAT 1211
A P P S SP++ + P + ++ +T EE P AA+ P P A +A
Sbjct: 567 ALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAA 626
Query: 1212 LEEFTSPAASVPTSEEPASLAAAVSNPEEPTS-PAAAVPTLEEPTSSAAAVLTPEELSSP 1270
PAA S PA A P P P A P SA + T E P
Sbjct: 627 CH----PAA---WSRGPAPPLAFRGAPGAPLPWPPATGP------GSADGLCTIYETEGP 673
Query: 1271 AASVPTP---EEPASPAAAVSNLEEPASPAAAVPTPEVAAI 1308
++ P P + SP + A A+ +P+ A +
Sbjct: 674 ESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARL 714
Score = 96.3 bits (238), Expect = 2e-19
Identities = 129/533 (24%), Positives = 189/533 (35%), Gaps = 84/533 (15%)
Query: 892 EEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGF 951
+ + A A + A P + P G SP P AA+ G + G
Sbjct: 4 KRDKAKAGAAARTPAARAPGLLTPRPPG--------SPRPPPPVTPAALRVLGAAGAVGR 55
Query: 952 SP----EWAALAITVPITEEDGTPEGPVTPATT---VHAPEEPDTAAVRVSTPEEPASPA 1004
P T+P + P P + AP +T+ VS+P +
Sbjct: 56 KPLAERAGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTT 115
Query: 1005 AAVP--------TPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPT--SPAAAVPTPEEPTS 1054
P + EE + A P+ A A PT +P+ A+
Sbjct: 116 RPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAG 175
Query: 1055 PAAAVPTPEEPTSPAAAVPTPEEPTSPAA----AVPTPEEPTSPAAA--VPTPEEPTSPA 1108
+P P P P + S A+ P+P P+A + P + +
Sbjct: 176 TEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS 235
Query: 1109 AAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVA------ 1162
+A P S +A TP PA P+ P + P P V P + A+ A+
Sbjct: 236 SATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRP-PQVTPPRKDAAPALGPLSSSP 294
Query: 1163 VPTPEESASPAAAVP-----------TPAESASFAAVVATLE--------EPTSPAASVP 1203
+ TP SA P+ + P TP A+ + TL+ P SP A+ P
Sbjct: 295 LATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPP 354
Query: 1204 ---TPAAMVATLEEFTSPAASVPTS-------EEPASLA-----AAVSNPEEPTSPAAAV 1248
PA + L+ SP AS P S + P +LA A S P P A
Sbjct: 355 PQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFS 414
Query: 1249 PTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVP--TPEVA 1306
P P S +A TP + P+ + P + P SP A+ P SP+A P P
Sbjct: 415 PPASPPVSPSA---TPPSQAPPSLAAPPLQVPPSPPAS-----PPMSPSATPPPQAPPPL 466
Query: 1307 AIPAASVPTPEVPAIPAAAVPPMEEV--SPIGVPFLGVSAHTDSVPISEEGTP 1357
A P + P A PA A PP++ + P P + + S+P+S TP
Sbjct: 467 AAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATP 519
Score = 84.7 bits (208), Expect = 6e-16
Identities = 105/403 (26%), Positives = 146/403 (36%), Gaps = 65/403 (16%)
Query: 1015 SPAAAVPTPEEPTSPAAAVPPPEEPTSPAA------AVPTPEEPTSPAAAV---PTPEEP 1065
+PAA P P P + PPP P +PAA A +P + A T E
Sbjct: 16 TPAARAPGLLTPRPPGSPRPPP--PVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPES 73
Query: 1066 TSPAAAVPTPEEPTSPAAAVPTPEEPTSPA-------AAVPTPEEPTSPAAAVPTPEEPA 1118
A T P S P + TSP A+ T P + EE
Sbjct: 74 APRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETV 133
Query: 1119 SPAAAVPTPEEPASPAAAV--PTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAV 1176
+ A P+ A A A + P P+PA+ +A V +P P SA P
Sbjct: 134 ARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPT 193
Query: 1177 PTPAESASFAAVVATLEEPTSPAA----------SVPTPAAMVATLEEFTSPAASVPTSE 1226
P +S S A+ +T E SPAA P ++ ++ +SPA S P++
Sbjct: 194 EGPRKSVSSASEHSTTEP--SPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSAR 251
Query: 1227 EPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAA 1286
A S P+ A P + P AA L P LSS + P+P P SP+A
Sbjct: 252 GTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP--LSSSPLATPSPSAPPSPSAP 309
Query: 1287 VSNLEEPASPA---------------------------AAVPTPEVAAIPAASVPTPEVP 1319
S P+ PA + + TP A PA ++P + P
Sbjct: 310 PSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAP 369
Query: 1320 AIPAAAVP--PMEEVSPIGVPFLGVSAHTDSVPISEEGTPVLE 1360
P A+ P P+ SP L V H P S +P ++
Sbjct: 370 PSPPASPPLSPLATPSPQAPNALAV--HLLQAPFSPPPSPPVQ 410
Score = 31.2 bits (69), Expect = 7.5
Identities = 48/191 (25%), Positives = 65/191 (34%), Gaps = 24/191 (12%)
Query: 829 PVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASI 888
P+LQ P A PT++ P P+ S G + AL P P +
Sbjct: 530 PLLQVPPSPPASPTLQAPRRPPTPGPDTSVS--------GPRLTLALAPGPPPPPSRSPS 581
Query: 889 VSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAV 948
+L D+ + SA S PEG A AA P+ A A G +
Sbjct: 582 STLSGPDLAGHSSSATSTPEELRGYDSGPEGGA--AASPPPDAELAACHPAAWSRGPAPP 639
Query: 949 AGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVP 1008
F A P+ T G T++ E P++A TP +P A P
Sbjct: 640 LAFRG-----APGAPLPWPPATGPGSADGLCTIYETEGPESA-----TP----APGALDP 685
Query: 1009 TPEEPTSPAAA 1019
P TS A
Sbjct: 686 GPSPGTSGGKA 696
>gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]
Length = 2639
Score = 113 bits (283), Expect = 1e-24
Identities = 117/491 (23%), Positives = 164/491 (33%), Gaps = 62/491 (12%)
Query: 904 PERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVP 963
P T P T+ + +P T V T G +P + T
Sbjct: 1313 PTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTT 1367
Query: 964 ITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTP 1023
+T TP G TP TT P T V+ P TP T+ PTP
Sbjct: 1368 VTPTP-TPTGTQTPTTT------PITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTP 1420
Query: 1024 EEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTP---EEPTS 1080
+P P T+ PT PT A PT TS PTP + PT+
Sbjct: 1421 TGTQTPTTT---PITTTTTVTPTPT---PTGTQAPTPTAITTTSTVTPTPTPTGTQTPTT 1474
Query: 1081 PAAAVPT--PEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVP 1138
T PT PTP T+ PTP P TP + P
Sbjct: 1475 TPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTP-TPTGTQTPTSTPITTTTTVTPTP 1533
Query: 1139 TPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAA----------VPTPAESASFAAV 1188
TP P PTP + + PTP + +P PTP + + V
Sbjct: 1534 TPTGTQTP---TPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTV 1590
Query: 1189 VAT-------LEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEP 1241
+ T PTS ++ TP T+ +P + + P S V+ P
Sbjct: 1591 LITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTP 1650
Query: 1242 TSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVP 1301
T+ + PT ++ A + S+P TP+ S + S L E + + +P
Sbjct: 1651 TTGSTG-----PPTHTSTAPIAELTTSNPPPESSTPQTSRSTS---SPLTESTTLLSTLP 1702
Query: 1302 TPEVAAIPAASVPTPEVPAIPAA----AVPPMEEVSPIGVPFLGVSAHTDSVPISEEGTP 1357
P + A TP P + + PP SP G P G + + S P TP
Sbjct: 1703 -PAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAP-----TP 1756
Query: 1358 VLEEASSTGMW 1368
+ ++T W
Sbjct: 1757 STVQTTTTSAW 1767
Score = 107 bits (266), Expect = 1e-22
Identities = 120/506 (23%), Positives = 165/506 (32%), Gaps = 63/506 (12%)
Query: 841 PTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEEEDVTAAA 900
PT P+P ++ + P P T P P T
Sbjct: 1313 PTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTG---------------TQTP 1357
Query: 901 VSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAI 960
+ P T P GT ++P T V T G +P +
Sbjct: 1358 TTTPITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTPTGTQ-----TPTSTPITT 1410
Query: 961 TVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAV 1020
T +T TP G TP TT P T V+ P A PT TS
Sbjct: 1411 TTTVTPTP-TPTGTQTPTTT------PITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPT 1463
Query: 1021 PTPE-------EPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTP---EEPTSP-- 1068
PTP P + V P PT PT T+ PTP + PTS
Sbjct: 1464 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPI 1523
Query: 1069 ---AAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVP 1125
PTP PT PTP T+ PTP +P TP + P
Sbjct: 1524 TTTTTVTPTPT-PTGTQTPTPTPISTTTTVTPTPTPTGTQTPTT---TPITTTTTVTPTP 1579
Query: 1126 TPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASF 1185
TP +P + T P PTP + S V TP + + A PTP + +
Sbjct: 1580 TPTGTQTPTTVLITTTTTMTP---TPTPTSTKSTTV---TPITTTTTVTATPTPTGTQTP 1633
Query: 1186 AAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEP-----ASLAAAVSNP-E 1239
+ + +P + PT + T+P A + TS P + + S+P
Sbjct: 1634 TMIPISTTTTVTPTPT-PTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLT 1692
Query: 1240 EPTSPAAAVPTLEEPTSSA--AAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPA 1297
E T+ + +P E TS+A + P S P P SP + S +
Sbjct: 1693 ESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSS 1752
Query: 1298 AAVPTPEVAAIPAASVPTPEVPAIPA 1323
A P+ +A PTP + P+
Sbjct: 1753 APTPSTVQTTTTSAWTPTPTPLSTPS 1778
Score = 102 bits (255), Expect = 2e-21
Identities = 95/398 (23%), Positives = 128/398 (32%), Gaps = 27/398 (6%)
Query: 975 VTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVP 1034
+T TT + P T V+ P S + PTP T+ PTP +P
Sbjct: 1303 MTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQTPTTT-- 1360
Query: 1035 PPEEPTSPAAAVPTP---EEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEP 1091
P T+ PTP + PT+ T PT TP TP P
Sbjct: 1361 -PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTP-TP 1418
Query: 1092 TSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVP 1151
T PT T+ PTP + A PTP + + PTP P
Sbjct: 1419 TPTGTQTPTTTPITTTTTVTPTPTPTGTQA---PTPTAITTTSTVTPTPTPTGTQTPTT- 1474
Query: 1152 TPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVAT 1211
TP + + PTP PTP + V T PT TP T
Sbjct: 1475 TPITTTTTVTPTPTP-----TGTQTPTPTAITTTTTVTPT-PTPTGTQTPTSTPITTTTT 1528
Query: 1212 LEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPA 1271
+ +P + + P S V+ PT T T++ TP +P
Sbjct: 1529 VTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 1588
Query: 1272 ASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIPA-AAVPPME 1330
+ T +P P S + TP + PTP P +
Sbjct: 1589 TVLITTTTTMTPTPT------PTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTT 1642
Query: 1331 EVSPIGVPFLGVS---AHTDSVPISEEGTPVLEEASST 1365
V+P P G + HT + PI+E T SST
Sbjct: 1643 TVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESST 1680
Score = 90.1 bits (222), Expect = 1e-17
Identities = 113/491 (23%), Positives = 162/491 (32%), Gaps = 65/491 (13%)
Query: 858 TSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVP 917
T++ P P GT P + + T P T + P
Sbjct: 1412 TTVTPTPTPTGTQT-------PTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTP 1464
Query: 918 EGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTP 977
T ++P T V T G +P A+ T +T TP G TP
Sbjct: 1465 TPTGTQTPTTTPITTTTTVTPTPTPTGTQ-----TPTPTAITTTTTVTPTP-TPTGTQTP 1518
Query: 978 A-----TTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAA 1032
TT P + TP ++ PTP PT TP T+
Sbjct: 1519 TSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPT-PTGTQTPTTTPITTTTTVTP 1577
Query: 1033 VPPPEEPTSPAAAV--------PTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPA-- 1082
P P +P + PTP PTS + TP T+ A PTP +P
Sbjct: 1578 TPTPTGTQTPTTVLITTTTTMTPTPT-PTSTKSTTVTPITTTTTVTATPTPTGTQTPTMI 1636
Query: 1083 ------AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPT---PEEPASP----AAAVPTPEE 1129
PTP PT+ + PT T+P A + T P E ++P + + P E
Sbjct: 1637 PISTTTTVTPTPT-PTTGSTGPPT-HTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTES 1694
Query: 1130 PASPAAAVPTPEEPAFPAPAVPT-PEESASAAVAVPTPEESASPAAAVPTPAESASFAAV 1188
+ P E + P+ PT P ++ P P + SP + S +A
Sbjct: 1695 TTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAP 1754
Query: 1189 VATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSN-----PEEPTS 1243
+ + T+ +A PTP + T+ P+S L V N P E
Sbjct: 1755 TPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSV----LICCVLNDTYYAPGEEVY 1810
Query: 1244 PAAAVPTLEEPTSSAAAVL---------TPEELSSPAASVPTPEEPAS-PAAAVSNLEEP 1293
T S + L TP +P+ S PTP +P+S P+ + P
Sbjct: 1811 NGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPP 1870
Query: 1294 ASPAAAVPTPE 1304
P P E
Sbjct: 1871 ECPDFDPPRQE 1881
Score = 32.3 bits (72), Expect = 3.3
Identities = 35/180 (19%), Positives = 56/180 (31%), Gaps = 13/180 (7%)
Query: 1194 EPTSPAASVPTPAAM-----VATLEEFTSPAASVPTSEE-----PASLAAAVSNPEEPTS 1243
E P +P + V E T P T+ E P + V+ PTS
Sbjct: 1271 EDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPTPITTTTTVTPTPTPTS 1330
Query: 1244 PAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEP-ASPAAAVPT 1302
+ PT T++ TP +P + T +P + + P +P T
Sbjct: 1331 TQSTTPTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 1390
Query: 1303 PEVAAIPAASVPTPEVPAIPAAAVPPMEEVSPIGVPFLGVSAHTDSVPISEEGTPVLEEA 1362
P + P V P +P G + T + ++ TP +A
Sbjct: 1391 VTPTPTPTGTQTPTSTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQA 1448
Score = 31.2 bits (69), Expect = 7.5
Identities = 16/47 (34%), Positives = 23/47 (48%), Gaps = 1/47 (2%)
Query: 995 STPEEPASPAAAVPTPEEPTS-PAAAVPTPEEPTSPAAAVPPPEEPT 1040
STP +P+ + PTP +P+S P+ P + P P P E T
Sbjct: 1838 STPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECPDFDPPRQENET 1884
>gi|16554449 zonadhesin isoform 3 [Homo sapiens]
Length = 2812
Score = 112 bits (280), Expect = 3e-24
Identities = 138/522 (26%), Positives = 202/522 (38%), Gaps = 63/522 (12%)
Query: 868 GTAVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVS 927
GT V L P V+ + S + T + P V++ P T V
Sbjct: 532 GTCPVKVLPELPP----VSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVP 587
Query: 928 SPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEP 987
+ T P I+ E + P + T+P + E P P+ P E
Sbjct: 588 KEKPTIPTEKPTISTE-KPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEK 646
Query: 988 DTAAVRVST--PEEPASPAAAVPTP-EEPTSPAA--AVPTPEEPTSPAAAVPPPEEPTSP 1042
T + T EEP +P T EEP P ++PT E+P+ P E T
Sbjct: 647 PTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPT-EKPSIPTEKPTISMEETII 705
Query: 1043 AAAVPT--PEEPTSPAA--AVPT------PEEPTSPAA--AVPTPEEPTSPAAAVPTPEE 1090
+ PT PE+PT P +PT PE+PT+P +PT + SP E+
Sbjct: 706 STEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEK 765
Query: 1091 PT-SPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVP-TPEEPAFP-- 1146
PT SP E+PT P P E + + EEP +P + E+P+ P
Sbjct: 766 PTISPEKLTIPTEKPTIPTEKPTIPTEKPTIST-----EEPTTPTEETTISTEKPSIPME 820
Query: 1147 APAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPT-- 1204
P +PT E + S EE+ + P E + + E+PT P PT
Sbjct: 821 KPTLPTEETTTSV-------EETTISTEKLTIPMEKPTIST-----EKPTIPTEK-PTIS 867
Query: 1205 PAAMVATLEEFTSPA--ASVPTSEEPASLAAAVSNPEEPT-SPAAAVPTLEEPTSSAAAV 1261
P + E+ T P ++P E S E+PT SP + E+PT
Sbjct: 868 PEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKP 927
Query: 1262 LTPEE---LSSPAASVPTPEEPASPAAAVSNLEEP--ASPAAAVPTPEVAAIPA--ASVP 1314
P E +S+ ++PT + SP E+P ++ +PT E IP ++P
Sbjct: 928 TIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPT-EKLTIPTEKPTIP 986
Query: 1315 TPEVPAIP----AAAVPPMEEVSPIGVPFLGVSAHTDSVPIS 1352
T E P IP A PP + G+ L +S H S P++
Sbjct: 987 T-EKPTIPTEKLTALRPPHPSPTATGLAALVMSPHAPSTPMT 1027
Score = 78.6 bits (192), Expect = 4e-14
Identities = 109/455 (23%), Positives = 168/455 (36%), Gaps = 59/455 (12%)
Query: 834 PSRTAAVPTVKDALDAALPS-----PEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASI 888
PS + T K + + P+ P T VP E T P E+ +
Sbjct: 622 PSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTT--------PTEE----TT 669
Query: 889 VSLEEEDVTAAAVSAP-ERATVPAV--TVSVPEGTAAVA--AVSSPEETAPAVAAAITQE 943
S+EE + S P E+ ++P T+S+ E + +S + T P I E
Sbjct: 670 TSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTE 729
Query: 944 GMSAVAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTP-EEPAS 1002
S ++ P T+P + +PE P TP E+P + +++ P E+P
Sbjct: 730 -KSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPT------EKPTISPEKLTIPTEKPTI 782
Query: 1003 PAAAVPTP-EEPTSPAAAVPTPEEPTSPAAAVP--PPEEPTSPAAAVPTPEEPTSPAA-- 1057
P P E+PT TP E T+ + P P E+PT P T E T+ +
Sbjct: 783 PTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEK 842
Query: 1058 -AVP------TPEEPTSPAAAVPT--PEEPTSPAAAVPTP-EEPTSPAA---------AV 1098
+P + E+PT P PT PE+ T P + P E+PT P +
Sbjct: 843 LTIPMEKPTISTEKPTIPTEK-PTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTI 901
Query: 1099 PTPEEPTSPAAAVPTPEEPASPAA--AVPTPEEPASPAAAVPTPEEPAFPAP--AVPTPE 1154
PT + SP + E+P P +PT E S E+P +PT +
Sbjct: 902 PTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEK 961
Query: 1155 ESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEE 1214
+ S E+ P P E + T P P+ + AA+V +
Sbjct: 962 PTISTEKPTIPTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPHA 1021
Query: 1215 FTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVP 1249
++P SV S ++ P + A P
Sbjct: 1022 PSTPMTSVILGTTTTSRSSTERCPPNARYESCACP 1056
Score = 50.4 bits (119), Expect = 1e-05
Identities = 66/299 (22%), Positives = 112/299 (37%), Gaps = 27/299 (9%)
Query: 834 PSRTAAVPTVKDALDAALPS-PEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLE 892
P+ +PT K + P+ P E T+I+ E ++ P E+ + S+E
Sbjct: 783 PTEKPTIPTEKPTISTEEPTTPTEETTIST----EKPSIPMEKPTLPTEE----TTTSVE 834
Query: 893 EEDVTAAAVSAP-ERATVPAVTVSVPEGTAAVAAVSSPEE-TAPAVAAAITQEGMSAVAG 950
E ++ ++ P E+ T+ ++P + SPE+ T P I E +
Sbjct: 835 ETTISTEKLTIPMEKPTISTEKPTIPTEKPTI----SPEKLTIPTEKLTIPTE-KPTIPI 889
Query: 951 FSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTP 1010
+ +T+P + +PE P P E T +T ++ +PT
Sbjct: 890 EETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTI---STEKLTIPTE 946
Query: 1011 EEPTSPAA-AVPTP------EEPTSPAAAVP-PPEEPTSPAAAVPTPEEPTSPAAAVPTP 1062
+ SP +PT E+PT P + P E+PT P P E +
Sbjct: 947 KPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPS 1006
Query: 1063 EEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPA 1121
T AA V +P P++P +V TS ++ P + A P + P+
Sbjct: 1007 PTATGLAALVMSPHAPSTPMTSVILGTTTTSRSSTERCPPNARYESCACPASCKSPRPS 1065
>gi|27881494 zonadhesin isoform 6 [Homo sapiens]
Length = 2721
Score = 112 bits (280), Expect = 3e-24
Identities = 138/522 (26%), Positives = 202/522 (38%), Gaps = 63/522 (12%)
Query: 868 GTAVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVS 927
GT V L P V+ + S + T + P V++ P T V
Sbjct: 532 GTCPVKVLPELPP----VSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVP 587
Query: 928 SPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEP 987
+ T P I+ E + P + T+P + E P P+ P E
Sbjct: 588 KEKPTIPTEKPTISTE-KPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEK 646
Query: 988 DTAAVRVST--PEEPASPAAAVPTP-EEPTSPAA--AVPTPEEPTSPAAAVPPPEEPTSP 1042
T + T EEP +P T EEP P ++PT E+P+ P E T
Sbjct: 647 PTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPT-EKPSIPTEKPTISMEETII 705
Query: 1043 AAAVPT--PEEPTSPAA--AVPT------PEEPTSPAA--AVPTPEEPTSPAAAVPTPEE 1090
+ PT PE+PT P +PT PE+PT+P +PT + SP E+
Sbjct: 706 STEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEK 765
Query: 1091 PT-SPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVP-TPEEPAFP-- 1146
PT SP E+PT P P E + + EEP +P + E+P+ P
Sbjct: 766 PTISPEKLTIPTEKPTIPTEKPTIPTEKPTIST-----EEPTTPTEETTISTEKPSIPME 820
Query: 1147 APAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPT-- 1204
P +PT E + S EE+ + P E + + E+PT P PT
Sbjct: 821 KPTLPTEETTTSV-------EETTISTEKLTIPMEKPTIST-----EKPTIPTEK-PTIS 867
Query: 1205 PAAMVATLEEFTSPA--ASVPTSEEPASLAAAVSNPEEPT-SPAAAVPTLEEPTSSAAAV 1261
P + E+ T P ++P E S E+PT SP + E+PT
Sbjct: 868 PEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKP 927
Query: 1262 LTPEE---LSSPAASVPTPEEPASPAAAVSNLEEP--ASPAAAVPTPEVAAIPA--ASVP 1314
P E +S+ ++PT + SP E+P ++ +PT E IP ++P
Sbjct: 928 TIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPT-EKLTIPTEKPTIP 986
Query: 1315 TPEVPAIP----AAAVPPMEEVSPIGVPFLGVSAHTDSVPIS 1352
T E P IP A PP + G+ L +S H S P++
Sbjct: 987 T-EKPTIPTEKLTALRPPHPSPTATGLAALVMSPHAPSTPMT 1027
Score = 78.6 bits (192), Expect = 4e-14
Identities = 109/455 (23%), Positives = 168/455 (36%), Gaps = 59/455 (12%)
Query: 834 PSRTAAVPTVKDALDAALPS-----PEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASI 888
PS + T K + + P+ P T VP E T P E+ +
Sbjct: 622 PSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTT--------PTEE----TT 669
Query: 889 VSLEEEDVTAAAVSAP-ERATVPAV--TVSVPEGTAAVA--AVSSPEETAPAVAAAITQE 943
S+EE + S P E+ ++P T+S+ E + +S + T P I E
Sbjct: 670 TSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTE 729
Query: 944 GMSAVAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTP-EEPAS 1002
S ++ P T+P + +PE P TP E+P + +++ P E+P
Sbjct: 730 -KSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPT------EKPTISPEKLTIPTEKPTI 782
Query: 1003 PAAAVPTP-EEPTSPAAAVPTPEEPTSPAAAVP--PPEEPTSPAAAVPTPEEPTSPAA-- 1057
P P E+PT TP E T+ + P P E+PT P T E T+ +
Sbjct: 783 PTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEK 842
Query: 1058 -AVP------TPEEPTSPAAAVPT--PEEPTSPAAAVPTP-EEPTSPAA---------AV 1098
+P + E+PT P PT PE+ T P + P E+PT P +
Sbjct: 843 LTIPMEKPTISTEKPTIPTEK-PTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTI 901
Query: 1099 PTPEEPTSPAAAVPTPEEPASPAA--AVPTPEEPASPAAAVPTPEEPAFPAP--AVPTPE 1154
PT + SP + E+P P +PT E S E+P +PT +
Sbjct: 902 PTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEK 961
Query: 1155 ESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEE 1214
+ S E+ P P E + T P P+ + AA+V +
Sbjct: 962 PTISTEKPTIPTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPSPTATGLAALVMSPHA 1021
Query: 1215 FTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVP 1249
++P SV S ++ P + A P
Sbjct: 1022 PSTPMTSVILGTTTTSRSSTERCPPNARYESCACP 1056
Score = 50.4 bits (119), Expect = 1e-05
Identities = 66/299 (22%), Positives = 112/299 (37%), Gaps = 27/299 (9%)
Query: 834 PSRTAAVPTVKDALDAALPS-PEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLE 892
P+ +PT K + P+ P E T+I+ E ++ P E+ + S+E
Sbjct: 783 PTEKPTIPTEKPTISTEEPTTPTEETTIST----EKPSIPMEKPTLPTEE----TTTSVE 834
Query: 893 EEDVTAAAVSAP-ERATVPAVTVSVPEGTAAVAAVSSPEE-TAPAVAAAITQEGMSAVAG 950
E ++ ++ P E+ T+ ++P + SPE+ T P I E +
Sbjct: 835 ETTISTEKLTIPMEKPTISTEKPTIPTEKPTI----SPEKLTIPTEKLTIPTE-KPTIPI 889
Query: 951 FSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTP 1010
+ +T+P + +PE P P E T +T ++ +PT
Sbjct: 890 EETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTI---STEKLTIPTE 946
Query: 1011 EEPTSPAA-AVPTP------EEPTSPAAAVP-PPEEPTSPAAAVPTPEEPTSPAAAVPTP 1062
+ SP +PT E+PT P + P E+PT P P E +
Sbjct: 947 KPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPHPS 1006
Query: 1063 EEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPA 1121
T AA V +P P++P +V TS ++ P + A P + P+
Sbjct: 1007 PTATGLAALVMSPHAPSTPMTSVILGTTTTSRSSTERCPPNARYESCACPASCKSPRPS 1065
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 110 bits (275), Expect = 1e-23
Identities = 129/448 (28%), Positives = 168/448 (37%), Gaps = 60/448 (13%)
Query: 912 VTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTP 971
+ S+PEG + +VS+ + + ++ + +T +TEE+
Sbjct: 418 IPFSLPEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEE-EK 476
Query: 972 EGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAV------PTPEEPTSPAAAVPTPEE 1025
E EE + T PA AA+ P EE SPA A +E
Sbjct: 477 EAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKE 536
Query: 1026 PTSPAAAVPPPEEPTSPA---------AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPE 1076
A V PE+ SPA A P EE SP A V +PE+ SPA E
Sbjct: 537 EAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSP-AEVKSPEKAKSPA-----KE 590
Query: 1077 EPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAA 1136
E SPA A +PE+ S P EE SPA A +E A A V +PE+ S
Sbjct: 591 EAKSPAEA-KSPEKAKS-----PVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKS---- 640
Query: 1137 VPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPT 1196
PT EE P A +E A +PE++ SP A E A + P
Sbjct: 641 -PTKEEAKSPEKAKSPEKEEAK------SPEKAKSPVKAEAKSPEKA---------KSPV 684
Query: 1197 SPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSN-PEEPTSPAAAVPTLEEPT 1255
A P A E + A P EE S A S EE +P A ++E
Sbjct: 685 KAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEA 744
Query: 1256 SSAAAVLTPE-----ELSSPAASVPTPEEPASPAAAVSNLEEPASPA-AAVPTPEVAAIP 1309
S +PE ++ SP A P EE SPA E+ SP V +PE A P
Sbjct: 745 KSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFP--EKAKSPVKEEVKSPEKAKSP 802
Query: 1310 A---ASVPTPEVPAIPAAAVPPMEEVSP 1334
A P E+P P EE P
Sbjct: 803 LKEDAKAPEKEIPKKEEVKSPVKEEEKP 830
Score = 102 bits (254), Expect = 3e-21
Identities = 152/569 (26%), Positives = 209/569 (36%), Gaps = 83/569 (14%)
Query: 757 ESEILSLHLLVEELRLNPDGVETVNDTKPELNVASSEGGEMERRDSDSFLNIFPEKQVTK 816
E E + + EE ++ + E E EGGE E + ++ TK
Sbjct: 451 EKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGG--------EEETK 502
Query: 817 AGNTEPVLEEWIPVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALV 876
+ E ++ +++ K +A P EE S A V +PE A
Sbjct: 503 SPPAEEAASP-----EKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPE-----KAKS 552
Query: 877 PFPHEDILVASIVSLEEEDVTAAA-VSAPERATVPAV--TVSVPEGTAAVAAVSSPEETA 933
P E S E+E+ + A V +PE+A PA S E + A S +E A
Sbjct: 553 PAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEA 612
Query: 934 PAVAAA---ITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTA 990
+ A A + +E S SPE A P EE +PE +PE+ +
Sbjct: 613 KSPAEAKSPVKEEAKSPAEVKSPEKAKS----PTKEEAKSPE-------KAKSPEKEEA- 660
Query: 991 AVRVSTPEEPASPAAA-VPTPEEPTSPAAA-VPTPEEPTSPAAAVPPPEEPTSPAAAV-P 1047
+PE+ SP A +PE+ SP A +PE+ SP EE SP A P
Sbjct: 661 ----KSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVK-----EEAKSPEKAKSP 711
Query: 1048 TPEEPTSPAAAV-PTPEEPTSPAAAV-PTPEEPTSPAAAVPTPEEPT----SPAAAVPTP 1101
EE SP A P EE +P A P EE SP A + T SP A P
Sbjct: 712 VKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAK 771
Query: 1102 EEPTSPA------AAVPTPEEPASPAAAV-PTPEEPASPAAAVPTPEEPAFPAPAVPTPE 1154
EE SPA A P EE SP A P E+ +P +P EE P P+
Sbjct: 772 EEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQ 831
Query: 1155 ESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEE 1214
E V V P + A A TP T E+ S P A +EE
Sbjct: 832 E-----VKVKEPPKKAEEEKAPATPK----------TEEKKDSKKEEAPKKEAPKPKVEE 876
Query: 1215 FTSPAASVP------TSEEPASLAAAVSNPEEPTSPAAAVPTLEEP-TSSAAAVLTPEEL 1267
PA P +E A V PE+ V +P + A P++
Sbjct: 877 KKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDA 936
Query: 1268 SSPAASVPTPEEPASPAAAVSNLEEPASP 1296
+ S P ++ A+P + E+ P
Sbjct: 937 KAKEPSKPAEKKEAAPEKKDTKEEKAKKP 965
Score = 71.2 bits (173), Expect = 7e-12
Identities = 118/521 (22%), Positives = 178/521 (34%), Gaps = 56/521 (10%)
Query: 716 DEDGEAKELDYQATLLEDQAPAHFHRNFP--EQVFQDLQRKSPESEILSLHLLVEELRLN 773
+E+ E E + ++ E+ A P E+ + KSPE E +
Sbjct: 491 EEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAK----------S 540
Query: 774 PDGVETVNDTKPELNVASSEGGEMERRDSDSFLNIFPEKQVTKAGNTEPVLEEWIPVLQR 833
P V++ K + E + + + + K KA + P EE +
Sbjct: 541 PAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKS--PAKEEAKSPAEA 598
Query: 834 PSRTAAVPTVKDAL----DAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASIV 889
S A VK+ +A P EE S A V +PE A P E
Sbjct: 599 KSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPE-----KAKSPTKEEAKSPEKAK 653
Query: 890 SLEEEDVTA---------AAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAI 940
S E+E+ + A +PE+A P V A + V ++ + +
Sbjct: 654 SPEKEEAKSPEKAKSPVKAEAKSPEKAKSP-VKAEAKSPEKAKSPVKEEAKSPEKAKSPV 712
Query: 941 TQEGMSAVAGFSP--EWAALAITV--PITEEDGTPEGPVTPATT----VHAPEEPDTAAV 992
+E S SP E A P+ EE +PE +P V +PE A
Sbjct: 713 KEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKE 772
Query: 993 RVSTPEEPASPAAAVPTPEEPTSPAAAV-PTPEEPTSPAAAVPPPEEPTSPAAAVPTPEE 1051
+P + A P EE SP A P E+ +P +P EE SP P+E
Sbjct: 773 EARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQE 832
Query: 1052 -----PTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVP------T 1100
P A P P + EE A P EE PA P
Sbjct: 833 VKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEA 892
Query: 1101 PEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPA-AAVPTPEEPAFPAPAVPTPEESASA 1159
+E VPTPE+ A V +P A P++ P+ P ++ A+
Sbjct: 893 KKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAP 952
Query: 1160 AVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAA 1200
E++ P T A++ ++ +EP+ P A
Sbjct: 953 EKKDTKEEKAKKPEEKPKTEAKAKEDDKTLS--KEPSKPKA 991
Score = 32.3 bits (72), Expect = 3.3
Identities = 72/336 (21%), Positives = 117/336 (34%), Gaps = 57/336 (16%)
Query: 720 EAKELDYQATLLEDQAPAHFHRNFPEQVFQDLQRKSPESEILSLHLLVEELRLNPDGVET 779
EAK + + ++++A + PE+ + L KSPE++ + EE R D
Sbjct: 729 EAKTPEKAKSPVKEEAKSPEKAKSPEKA-KTLDVKSPEAKTPAK----EEARSPADKFPE 783
Query: 780 VNDTKPELNVASSEGGEMERRDSDSFLNIFPEKQVTKAGNTE-PVLEEWIPVLQRPSRTA 838
+ + V S E + ++ PEK++ K + PV EE ++P
Sbjct: 784 KAKSPVKEEVKSPEKAKSPLKEDAKA----PEKEIPKKEEVKSPVKEE-----EKPQEVK 834
Query: 839 AVPTVKDALDA---ALPSPEEGTSIAAVPAPEGTAVVAALVPFPH-EDILVASIVSLEEE 894
K A + A P EE AP+ A P P E+ ++ +E
Sbjct: 835 VKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEA------PKPKVEEKKEPAVEKPKES 888
Query: 895 DVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPE 954
V A A ++ VP P A V E+ P + ++
Sbjct: 889 KVEAKKEEAEDKKKVPTPEKEAP------AKVEVKEDAKPKEKTEVAKK----------- 931
Query: 955 WAALAITVPITEEDGTPEGPVTPATTVHA-PEEPDTAAVRVSTPEEPASPAAAVPTPEEP 1013
+D + P PA A PE+ DT + PEE A ++
Sbjct: 932 ----------EPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKT 981
Query: 1014 TSPAAAVPTPEEPTSPAAA----VPPPEEPTSPAAA 1045
S + P E+ ++ PPE+ T AA
Sbjct: 982 LSKEPSKPKAEKAEKSSSTDQKDSKPPEKATEDKAA 1017
>gi|91982772 mucin 17 [Homo sapiens]
Length = 4493
Score = 110 bits (274), Expect = 1e-23
Identities = 155/653 (23%), Positives = 242/653 (37%), Gaps = 93/653 (14%)
Query: 789 VASSEGGEMERRDSDSFLNIFPEKQVTKAGNTEPVLEEWIPVLQRPSRTAAVPT------ 842
VASSE G + D+ P TKA ++ E + + S + + T
Sbjct: 2822 VASSEAGTLSTTPVDTST---PVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVST 2878
Query: 843 --VKDALDAALPSPEEGTSIAAVPAPEG----TAVVAALVPFPHEDILVASIVSLEEEDV 896
V + + L + TSI + EG T +P + + S+ V
Sbjct: 2879 TPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTV 2938
Query: 897 TAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWA 956
A A +T P V P T+A A SS TA + I+ G +P +
Sbjct: 2939 PVAGSEASTLSTTP-VDTRTPVTTSAEA--SSSPTTAEGTSMPISTPGERR----TPLTS 2991
Query: 957 ALAITVPITEEDG-----TPEGPVTPATT-VHAPEEPDTA---AVRVSTPEEPASPAAAV 1007
T+P+ + TP TP TT A P TA + +STP E ++P ++
Sbjct: 2992 MSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSI 3051
Query: 1008 PTPEEPTS-PAAAV--PTPEEPTSPA------AAVPPPEEPTSPAAAVPTPEEPTSPAAA 1058
P P + P A+ TP + SP ++ P P E TS + T E ++P
Sbjct: 3052 PVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTS--MPISTYSEGSTPLTG 3109
Query: 1059 VPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEP-----TSPAAAVPT--PEEPTSPAAAV 1111
VP P + +A P + V T E TS ++PT P E ++P +
Sbjct: 3110 VPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYM 3169
Query: 1112 PTPE-------------EPASPAAAVPTPEEPASPAAA------VPTPEEPAFPAPAVP- 1151
P P + V T E S A TP E P +VP
Sbjct: 3170 PVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPV 3229
Query: 1152 --TPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAA-------SV 1202
TP S+ A++ TP +S +P + T E++S PTS + S+
Sbjct: 3230 SNTPVASSEASILSTTPVDSNTP---LTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSM 3286
Query: 1203 PTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTL-----EEPTSS 1257
P VA+ E T TS + + A S+P P + ++PT P ++
Sbjct: 3287 PVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSP--PIADGTSMPTSTYSEGSTPLTN 3344
Query: 1258 AAAVLTPEELSSPAASVPTPEEPASP--AAAVSNLEEPASPAAAVPT--PEVAAIPAASV 1313
+ TP S + TP + ++P + ++L + ++PT P P AS+
Sbjct: 3345 MSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASM 3404
Query: 1314 PTPEVPAIPAAAVPPMEEVSPIGVPFLGVSAHTDSVPISEEGTPVLEEASSTG 1366
P P + ++ V + + S S P EGT + +S G
Sbjct: 3405 PVSTTPVV-SSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEG 3456
Score = 107 bits (268), Expect = 6e-23
Identities = 145/614 (23%), Positives = 227/614 (36%), Gaps = 99/614 (16%)
Query: 819 NTEPVLEEWIPVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPF 878
NT V L + P ++ P+ +G S+ EG+ + ++
Sbjct: 696 NTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSM--- 752
Query: 879 PHEDILV----ASIVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAP 934
P L+ AS +S D + ++ E + P T EGT+ +S+P E +P
Sbjct: 753 PVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTT----EGTSM--PISTPSEGSP 806
Query: 935 AVAAAITQEGMSAVAGFSPEWAALAITVPI---------TEEDGTP---EGPVTPATTVH 982
+T +S SPE + L+ T P+ TE +P EG P +T
Sbjct: 807 L----LTSIPVSITPVTSPEASTLS-TTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYS 861
Query: 983 APEEP-------------------DTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTP 1023
P T V STP ++ A + PT E TS + TP
Sbjct: 862 EGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTS--TP 919
Query: 1024 EEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSP-----AAAVPT--PE 1076
E ++P ++P P + A P + V T E TS ++PT P
Sbjct: 920 GEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPS 979
Query: 1077 EPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAA 1136
E T+P + P + + A P + T E +SP PT E + P +
Sbjct: 980 EGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPP---PTAEGTSMPTST 1036
Query: 1137 VPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFA----AVVATL 1192
P P T S+ + TP ++++P + S++ A +T
Sbjct: 1037 PSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTY 1096
Query: 1193 EEPTSPAASVPTPAAMVATLEEFT---------------SPAASVPTSEEPASLAAAVSN 1237
E ++P SVP +V + E T + A+S PT+ E S+ S
Sbjct: 1097 SEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSI--PTSP 1154
Query: 1238 PEEPTSPAAAVP-TLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASP 1296
P E T+P A++P + SS A L+ + S V T E +SP P S
Sbjct: 1155 PSEGTTPLASMPVSTTLVVSSEANTLSTTPVDS-KTQVATSTEASSPPPTAEVTSMPTS- 1212
Query: 1297 AAAVPTPEVAAIPAASVPTPEVPAIPAAA----VPPMEEVSPIGVPFLGVSAHTDSVPIS 1352
TP + P S+P P + A P++ +P+ SA T S P +
Sbjct: 1213 -----TPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPV-----TTSAETSSSPTT 1262
Query: 1353 EEGTPVLEEASSTG 1366
EGT + +S G
Sbjct: 1263 AEGTSLPTSTTSEG 1276
Score = 107 bits (268), Expect = 6e-23
Identities = 140/608 (23%), Positives = 226/608 (37%), Gaps = 121/608 (19%)
Query: 841 PTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEEEDVTAAA 900
P V ++ P+P EGTS+ EG+ + V + VT++A
Sbjct: 3076 PVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTG--------------VPVSTTPVTSSA 3121
Query: 901 VSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAI 960
+S +T P V S P T+ A S ++ + EG + + + P L +
Sbjct: 3122 IST--LSTTP-VDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLT-YMPVSTMLVV 3177
Query: 961 TVPITEEDGTPEGPVTPATTVHAPEEPDTA---AVRVSTPEEPASPAAAVPTPEEPTSPA 1017
+ + TP TP TT TA ++ STP E +P +VP P + +
Sbjct: 3178 SSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASS 3237
Query: 1018 AAV---PTPEEPTSP------AAAVPPPEEPTSPAAAVPTPEEPTSPAAAVP-------- 1060
A TP + +P A++ PP E TS + TP E ++P ++P
Sbjct: 3238 EASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTS--TPSEGSTPLTSMPVSTTTVAS 3295
Query: 1061 --------TPEEPTSP-------AAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPT 1105
TP + ++P +++ P + + P + P + + TP +
Sbjct: 3296 SETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSS 3355
Query: 1106 SPAAAVPTPEEPASP------AAAVPTPEEPAS-PAAAVPTPEEPAFPAPAVPTPEESAS 1158
+ TP + ++P A+ PT E S P ++ P P TP S+
Sbjct: 3356 EASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSE 3415
Query: 1159 AAVAVPTPEES------ASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATL 1212
TP +S ++ A++ PT AE S +T E ++P + +P VA+
Sbjct: 3416 VNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLP--TSTTSEGSTPLSIMPLSTTPVASS 3473
Query: 1213 EEFT---------------SPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEP--- 1254
E T SP S PT+ E S+ + + E ++P +P P
Sbjct: 3474 EASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAG--EGSTPLTNMPVSTTPVAS 3531
Query: 1255 -----------------TSSAAAVLTPEELSSPAASVPTPEEPASPAAAV---------S 1288
TSS+ A +P L + TP E +S + S
Sbjct: 3532 SEASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSS 3591
Query: 1289 NLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPMEEVSPIGVPFLGVSAHTDS 1348
P++P+ TP + + S PTP P PM S + P + T S
Sbjct: 3592 EASTPSTPSVDRSTPVTTSTQSNSTPTP-----PEVITLPMSTPSEVSTPLTIMPVSTTS 3646
Query: 1349 VPISEEGT 1356
V ISE GT
Sbjct: 3647 VTISEAGT 3654
Score = 104 bits (259), Expect = 7e-22
Identities = 145/650 (22%), Positives = 242/650 (37%), Gaps = 88/650 (13%)
Query: 781 NDTKPELNVASSEGGEMERRDSDSFLNIFPEKQVTKAGNTEPVLEEWIPVLQRPSRTAAV 840
N T+ + +SEG M F V+ T PV+ L +
Sbjct: 2194 NSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVS----TMPVVTSEASTLSATPVDTST 2249
Query: 841 PTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEEEDV---- 896
P + P+ EGTSI EGT + + +P H + + + +L V
Sbjct: 2250 PVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTS-IPVSHTLVANSEVSTLSTTPVDSNT 2308
Query: 897 ---TAAAVSAP----ERATVPAVTVS--------VPEGTAAVAAV-SSPEETAPAVAAAI 940
T+ S+P E ++P T S +P T VA+ +S T PA +
Sbjct: 2309 PFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTS-- 2366
Query: 941 TQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTPATTV---------HAPEEPDTAA 991
T + AG SP A T +G+ P +T+ H+ DT+
Sbjct: 2367 TPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTST 2426
Query: 992 VRVSTPEEPASPAAA----VPT--PEEPTSPAAAVPTPEEP----------TSPAAAVPP 1035
++ E +SP A +PT P E T+P A++P P T+P P
Sbjct: 2427 PVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTP 2486
Query: 1036 PEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPA 1095
T +++ T E+ P + T E ++ ++P P + A P
Sbjct: 2487 MTTSTEASSSPTTAEDIVVP---ISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSN 2543
Query: 1096 AAVPTPEEPTSPAAA-------VPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAP 1148
+ V T E +S A + T E ++P ++P +P + + A P +
Sbjct: 2544 SPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSI 2603
Query: 1149 AVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAM 1208
V T E++S+ PT + S + P+ ++ + +V+T+ +S A+++ T
Sbjct: 2604 PVTTSTETSSS----PTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVD 2659
Query: 1209 VATLEEFTSPAASVPTSEEPASLAAA------------------VSNPEEPTSPAAAVPT 1250
TL ++ +S PT+ E +S+ + ++N E T V T
Sbjct: 2660 TRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDT 2719
Query: 1251 LEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAA--VSNLEEPASPAAAVPTPEV-AA 1307
T+SA A +P + + TP + ++P + VS L +S A+ V T V +
Sbjct: 2720 STPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTS 2779
Query: 1308 IP-AASVPTPEVPAIPAAAVPPMEEVSPIGVPFLGVSAHTDSVPISEEGT 1356
IP S P P S P + + V SE GT
Sbjct: 2780 IPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGT 2829
Score = 103 bits (256), Expect = 2e-21
Identities = 132/593 (22%), Positives = 227/593 (38%), Gaps = 98/593 (16%)
Query: 839 AVPTVKDALDAALPSPEEGTSIAAVPAPEG----TAVVAALVPFPHEDILVASIVSLEEE 894
+ P A ++ P+ EGTS+ +G T+++ + +P + S +++
Sbjct: 2720 STPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTS 2779
Query: 895 ----------------DVTAAAVSAPERATVPAVTVSVPE--------GTAAVAAV--SS 928
+VT+ S P + P ++ V GT + V S+
Sbjct: 2780 IPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTST 2839
Query: 929 PEETAP-AVAAAITQEGMSAVAGFSPEWAALAITVPI-TEEDGTPEGPVTPATTVHAPEE 986
P T+ A ++ T EG+ + E + L ++P+ T + E T V
Sbjct: 2840 PVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIP 2899
Query: 987 PDTAAVRVSTPEEPASPAAAVPTPEEPTSP-----AAAVPTPEEPTSPAAAVP----PPE 1037
T+ S+P + + TP E ++P + VP S + P P
Sbjct: 2900 VTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPV 2959
Query: 1038 EPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVP---TPEEPTSP 1094
++ A++ PT E TS + TP E +P ++ P + + A TP + ++P
Sbjct: 2960 TTSAEASSSPTTAEGTS--MPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTP 3017
Query: 1095 AAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPE 1154
+ E +SP A T + TP E ++P ++P P A+P
Sbjct: 3018 VTT--STEASSSPTTAEGT-------GIPISTPSEGSTPLTSIPVSTTPV----AIPEAS 3064
Query: 1155 ESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVP---TPAAMVAT 1211
++ V +P +++ ++ PTPAE S ++T E ++P VP TP A
Sbjct: 3065 TLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMP--ISTYSEGSTPLTGVPVSTTPVTSSAI 3122
Query: 1212 LEEFTSP------------AASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAA 1259
T+P A S PT+ E S+ S P E ++P +P S
Sbjct: 3123 STLSTTPVDTSTPVTTSTEAHSSPTTSEGTSM--PTSTPSEGSTPLTYMPV------STM 3174
Query: 1260 AVLTPEE--LSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPE 1317
V++ E+ LS+ TP ++ A + + E + P + TP P SVP
Sbjct: 3175 LVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTS---TPSEGMTPLTSVPVSN 3231
Query: 1318 VPAIPAAA----VPPMEEVSPIGVPFLGVSAHTDSVPISEEGTPVLEEASSTG 1366
P + A P++ +P L S S P + EGT + S G
Sbjct: 3232 TPVASSEASILSTTPVDSNTP-----LTTSTEASSSPPTAEGTSMPTSTPSEG 3279
Score = 101 bits (252), Expect = 4e-21
Identities = 126/579 (21%), Positives = 219/579 (37%), Gaps = 71/579 (12%)
Query: 840 VPTVKDALDAALPSPEEGTSIAAVPAPEG----TAVVAALVPFPHEDILVASIVSLEEED 895
+P + ++ P+ EGTSI EG T+ A+ +P ++ S +S+ D
Sbjct: 304 IPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEM---STLSITPVD 360
Query: 896 VTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPE- 954
+ ++ E +++P + T+ ++ S+P P + S + +
Sbjct: 361 TSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDS 420
Query: 955 -----WAALAITVPITEED-----GTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPA 1004
A+ A + P T ED TP TP T++ P ++ + P
Sbjct: 421 KTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSK 480
Query: 1005 AAVPTPEE-----PTSPAAAVPT--PEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAA 1057
V T E PT+ ++PT P E ++P ++ P + + A P +
Sbjct: 481 TQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTST 540
Query: 1058 AVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEP 1117
V T E +S + TPE + P + TP E ++P +P + A T P
Sbjct: 541 PVTTSSEASSSST---TPEGTSIPTS---TPSEGSTPLTNMPVSTRLVVSSEASTTSTTP 594
Query: 1118 ASPAAAVPTPEEPASPAAAVPTPEEPA---------FPAPAVPTPEESASAAVAVPTPEE 1168
A V T E +S + P + +V T ++S A + T
Sbjct: 595 ADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPV 654
Query: 1169 SASPAAAVPTPAESASFAAV-----VATLEEPTSPAASVPTPAAMVATLEEFT------- 1216
++ T A S+S A +T E ++P S+P +VA+ E T
Sbjct: 655 DSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVD 714
Query: 1217 --------SPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEE-PTSSAAAVLTPEEL 1267
+ A+S PT+ + AS+ S P E ++P ++P + TSS A+ L+ L
Sbjct: 715 TSTPVTTSTEASSSPTTADGASM--PTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPL 772
Query: 1268 SSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVP 1327
+ + E SP ++P+ +P + +IP + P P +
Sbjct: 773 DTSTHITTSTEASCSPTTTEGTSMPISTPSEG--SPLLTSIPVSITPVTS-PEASTLSTT 829
Query: 1328 PMEEVSPIGVPFLGVSAHTDSVPISEEGTPVLEEASSTG 1366
P++ SP+ S S P EGT + S G
Sbjct: 830 PVDSNSPV-----TTSTEVSSSPTPAEGTSMPTSTYSEG 863
Score = 95.5 bits (236), Expect = 3e-19
Identities = 161/715 (22%), Positives = 254/715 (35%), Gaps = 122/715 (17%)
Query: 789 VASSEGGEMERRDSDSFLNIFPEKQVTKAGNTEPVLEEWIPVLQRPSRTAAVPTVKDALD 848
VA+SE + DS P T+A + P E PS + P + +
Sbjct: 995 VANSEASTLSTTPVDSNT---PLTTSTEASSPPPTAEGTSMPTSTPSE-GSTPLTRMPVS 1050
Query: 849 AALPSPEEGTSIAAVPAPEGTAVV-----------AALVPFPHEDILVASIVSLEEEDVT 897
+ + E ++++ PA T V A P S L V+
Sbjct: 1051 TTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGS-TPLTSVPVS 1109
Query: 898 AAAVSAPERATVPAVTV--SVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEW 955
V + E +T+ V S+P T+ A+ S ++ + EG + +A P
Sbjct: 1110 TRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASM-PVS 1168
Query: 956 AALAITVPITEEDGTPEGPVTP-ATTVHAPEEPDTAAVR---VSTPEEPASPAAAVPTPE 1011
L ++ TP T AT+ A P TA V STP E ++P ++P
Sbjct: 1169 TTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRH 1228
Query: 1012 EPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAA------------- 1058
P + + A P + V E +S PTS +
Sbjct: 1229 TPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTT 1288
Query: 1059 -VPTPEEPTSPAAAVPT--PEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVP--- 1112
V +PE T V T P ++ ++ PTP E TS + T E +P ++P
Sbjct: 1289 LVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTS--TYSEGRTPLTSIPVNT 1346
Query: 1113 -------------------TPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVP-- 1151
TP ++ A + PT E S + P E P ++P
Sbjct: 1347 TLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNS--NPSEGTTPLTSIPVS 1404
Query: 1152 -TPEESASAAVAVPTPEESASP----AAAVPTPAESASFAAVVATLEEPTSPAASVPTPA 1206
TP S+ A+ TP ++++P A A +P + + +T E +P S+P
Sbjct: 1405 TTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSN 1464
Query: 1207 AMVATLEEFT---------SP---AASVPTSEEPA-SLAAAVSNPEEPTSPAAAVPT--- 1250
VA E T SP + +V +S PA + A+S P E ++ ++P
Sbjct: 1465 TPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTT 1524
Query: 1251 ------LEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPE 1304
+ +++ A TP S A+S PT + S S E ++P ++P
Sbjct: 1525 TVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTS--MQTSTYSEGSTPLTSLPVST 1582
Query: 1305 VAAIPAASVPTPEVPAIPAAAVPPMEEVS----------PIGVPFLGVSAHTDSVPISEE 1354
+ + + + P V E S I P G S S+P+S
Sbjct: 1583 MLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEG-SPLLTSIPVST- 1640
Query: 1355 GTPVLEEASSTGMWIKEDLDSLVFGIKEV-------------TSTVLHGKVPLAA 1396
TPV +ST D +S V EV TST G+ PL +
Sbjct: 1641 -TPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPLTS 1694
Score = 95.5 bits (236), Expect = 3e-19
Identities = 147/595 (24%), Positives = 208/595 (34%), Gaps = 96/595 (16%)
Query: 841 PTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEEEDVTAAA 900
P V ++ P+P EGTSIA EG+ AL P VAS S T A
Sbjct: 1838 PVVTSTAVSSSPTPAEGTSIATSTPSEGST---ALTSIPVSTTTVAS--SETNTLSTTPA 1892
Query: 901 VSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAI 960
V++ T V+ S + S+P E P +T +S S E L+
Sbjct: 1893 VTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPP----LTSIPVSTTTVASSEINTLST 1948
Query: 961 TVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAV 1020
T+ T TP TT T A S P PA + P P S V
Sbjct: 1949 TLADTR---------TPVTTYSQASSSPTTADGTSMPT-PAYSEGSTPLTSMPLSTTLVV 1998
Query: 1021 P--------TPEEPTSPAAAVPPPEEPTSPAAA------VPTPEEPTSPAAAVPTPEEPT 1066
TP + ++PA E +SP A TP E T+P A +P
Sbjct: 1999 SSEASTLSTTPVDTSTPATT--STEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLV 2056
Query: 1067 SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAA------VPTPEEPTSPAAAVPTPEEP-AS 1119
+ P V E +S A A + P E + ++P P AS
Sbjct: 2057 VSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVAS 2116
Query: 1120 PAAAV--PTPEEPASPA------AAVPTPEE--------------PAFPAPAVPTPEESA 1157
P A+ TP + SP ++ P P E P P T S+
Sbjct: 2117 PEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASS 2176
Query: 1158 SAAVAVPTPEESASP------AAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVAT 1211
+ + TP ++++P A + PT +E S +T E ++P S+P V T
Sbjct: 2177 AISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPT--STPSEGSTPFTSMPVSTMPVVT 2234
Query: 1212 LEEFTSPAASVPTSEEPASLAAAVSNP-------------EEPTSPAAAVP---TLEEPT 1255
E T A V TS + A S+P E T+P ++P TL +
Sbjct: 2235 SEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANS 2294
Query: 1256 SSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTP----EVAAIPAA 1311
+ TP + ++P T E +SP P S ++ TP V+ A
Sbjct: 2295 EVSTLSTTPVDSNTP---FTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVA 2351
Query: 1312 SVPTPEVPAIPAAAVPPMEEVSPIG-VPFLGVSAHTDSVPISEEGTPVLEEASST 1365
S T + PA P+ S G P + SE TP+ ST
Sbjct: 2352 SFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVST 2406
Score = 94.0 bits (232), Expect = 9e-19
Identities = 125/577 (21%), Positives = 216/577 (37%), Gaps = 45/577 (7%)
Query: 819 NTEPVLEEWIPVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPF 878
+T PV+ + P ++ P+ EGTSI P EGT +A++ P
Sbjct: 2405 STMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASM-PV 2463
Query: 879 PHEDILV--ASIVSLEEEDVTAAAVSAPERATVP--AVTVSVPEGTAAVAAV---SSPEE 931
++ A +S D + ++ E ++ P A + VP TA+ + S P
Sbjct: 2464 STTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVS 2523
Query: 932 TAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAA 991
T P + + + V SP + I+ T +GT + T+ ++ +
Sbjct: 2524 TTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGT-----SMPTSTYSEGSTPLRS 2578
Query: 992 VRVSTPEEPASPAAAVPTPEEPTS--PAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTP 1049
+ VST +S A+ + T TS + T PT+ P P+ + ++ +
Sbjct: 2579 MPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSI 2638
Query: 1050 EEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAA 1109
T P A+ T+P T +++ T E + P + TP E ++P
Sbjct: 2639 LVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTS---TPGERSTPLT 2695
Query: 1110 AVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEES 1169
+ + + A P + V T E A + PT E S ++ P+ +
Sbjct: 2696 NILVSTTLLANSEASTLSTTPVDTSTPVTTSAE----ASSSPTTAEGTSMRISTPSDGST 2751
Query: 1170 ASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPT----- 1224
+ V T ++S A+ V+T TS + T A+ T E TS S P+
Sbjct: 2752 PLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTP 2811
Query: 1225 ------------SEEPASLAAA---VSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSS 1269
S E +L+ S P ++ A++ PT E + T E S+
Sbjct: 2812 LTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAE--GIVVPISTASEGST 2869
Query: 1270 PAASVPTPEEPASPAAAVSNLEEPASPAAAVPT-PEVAAIPAASVPTPEVPAIPAAAVPP 1328
S+P P + + A + P + V T E ++ P + T + P+ P
Sbjct: 2870 LLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTP 2929
Query: 1329 MEEVSPIGVPFLGVSAHTDSVPISEEGTPVLEEASST 1365
+ + VP G A T S + TPV A ++
Sbjct: 2930 LTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEAS 2966
Score = 92.0 bits (227), Expect = 4e-18
Identities = 142/641 (22%), Positives = 231/641 (36%), Gaps = 116/641 (18%)
Query: 819 NTEPVLEEWIPVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTA------VV 872
+T V I L + P + ++ P+ +GTS+ EG+ V
Sbjct: 1522 STTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVS 1581
Query: 873 AALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVP-EGTAAVAAVSSPEE 931
LV + L + + + + + S+ A ++T+S P EG+ + ++ P
Sbjct: 1582 TMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSI--PVS 1639
Query: 932 TAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTP-------EGPVTPATTVHAP 984
T P + + + V SP + ++ T +GT EG TP T++
Sbjct: 1640 TTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGR-TPLTSITVR 1698
Query: 985 EEP---------DTAAVRVSTPEEPASPAAAVPT-----------PEEPTSPAAAVPTPE 1024
P T V STP ++ A + PT P E T+P ++P
Sbjct: 1699 TTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVST 1758
Query: 1025 EPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPT----- 1079
P + A P + V T E TS PTS + TP T
Sbjct: 1759 TPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHT 1818
Query: 1080 ----SPAAAV-PTPEEPTSP------AAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPE 1128
S A+ + TP + SP ++ PTP E TS A TP E ++ ++P
Sbjct: 1819 LVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTS--IATSTPSEGSTALTSIPVST 1876
Query: 1129 EPASPAAAVPTPEEPAFPAPAVPT-------PEESASAAVAVPTPEESASPAAAVP---T 1178
+ + PA + V T P + +++ TP E P ++P T
Sbjct: 1877 TTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVSTT 1936
Query: 1179 PAESASFAAVVATLEEPTSP------AASVPTPA----AMVATLEEFTSPAASVP----- 1223
S+ + TL + +P A+S PT A E ++P S+P
Sbjct: 1937 TVASSEINTLSTTLADTRTPVTTYSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTL 1996
Query: 1224 -TSEEPASLAAA---VSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPT--- 1276
S E ++L+ S P ++ ++ PT TS + TP E ++P A +P
Sbjct: 1997 VVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTS--TPSERTTPLAGMPVSTT 2054
Query: 1277 ----------PEEPASPAAAVSNLEEPASPAAA-----------VPTPEVAAIPAASVPT 1315
P V+N E +S A A +P + +IP ++ P
Sbjct: 2055 LVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPV 2114
Query: 1316 PEVPAIPAAAVPPMEEVSPIGVPFLGVSAHTDSVPISEEGT 1356
P + P++ SP+ S S PI EGT
Sbjct: 2115 AS-PEASTLSTTPVDSNSPV-----ITSTEVSSSPIPTEGT 2149
Score = 91.3 bits (225), Expect = 6e-18
Identities = 153/714 (21%), Positives = 255/714 (35%), Gaps = 95/714 (13%)
Query: 761 LSLHLLVEELRLNPDGVETVNDTKPELNVASSEGGEMERRDSD--------SFLNIFPEK 812
LS H+ G + N +P + ++ S EM +S S + P +
Sbjct: 55 LSQHVRTGSAANTATGTTSTNVVEPRMYLSCSTNPEMTSIESSVTSDTPGVSSTRMTPTE 114
Query: 813 QVTKAGNTEPVLEEWIPVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVV 872
T + +T + + + + PT + D + +P E SI++ A TA +
Sbjct: 115 SRTTSESTS----DSTTLFPSSTEDTSSPTTPEGTDVPMSTPSE-ESISSTMAFVSTAPL 169
Query: 873 AALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVT--------VSVPEGTAAVA 924
+ + V L +++ + PE T+P T S+P T VA
Sbjct: 170 PSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVA 229
Query: 925 A------VSSPEE-------TAPAVAAAITQEGMS----AVAGFSPEWAALAITVPITEE 967
+ +++P E +A A ++ T EG S A +G S + ++V +
Sbjct: 230 SSEAITLLTTPVEISTPVTISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVS 289
Query: 968 DGTPEGPVTPA-------TTVHAPEEPDTA---AVRVSTPEEPASPAAAVPTPEEPTSPA 1017
TPA T+ A P TA ++ ST E ++P + P P + +
Sbjct: 290 SEASTLSTTPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATS 349
Query: 1018 AAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTS----------------PAAAVPT 1061
P + V EP+S +PT E TS P + +
Sbjct: 350 EMSTLSITPVDTSTLVTTSTEPSS----LPTTAEATSMLTSTLSEGSTPLTNMPVSTILV 405
Query: 1062 PEEPTSPAAAVPTPEEP----TSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEP 1117
S + +P + S A++ PT E TS A TP E ++P ++P P
Sbjct: 406 ASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTS--IATSTPSEGSTPLTSMPVSTTP 463
Query: 1118 ASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASP--AAA 1175
+ + A P V T E A +P + ++ TP E ++P + +
Sbjct: 464 VASSEASNLSTTPVDSKTQVTTSTE------ASSSPPTAEVNSMPTSTPSEGSTPLTSMS 517
Query: 1176 VPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTS------PAASVPTSEEPA 1229
V T ++S A+ ++T TS + + A+ +T E TS S P + P
Sbjct: 518 VSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPV 577
Query: 1230 SLAAAVSNPEEPTSPAAA-VPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVS 1288
S VS+ TS A T +S A++ T E +S S + + +VS
Sbjct: 578 STRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVS 637
Query: 1289 NLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIPAA--AVPPMEEVSPIGVPFLGVSAHT 1346
+S A+ + T V + + T + A P + P + +T
Sbjct: 638 TTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNT 697
Query: 1347 DSVPISEEG----TPVLEEASSTGMWIKEDLDSLVFGIKEVTSTVLHGKVPLAA 1396
V SE TPV T + G TST G PL +
Sbjct: 698 TLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTS 751
Score = 86.3 bits (212), Expect = 2e-16
Identities = 150/669 (22%), Positives = 238/669 (35%), Gaps = 127/669 (18%)
Query: 828 IPVLQRPSRTAAVPTVKDA-LDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVA 886
+PV P ++ + +D+ P + ++ P EGT++ + P E
Sbjct: 3227 VPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTST---PSEGS--T 3281
Query: 887 SIVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMS 946
+ S+ T A+ +T PA T S P T + A+ S P ++ + EG +
Sbjct: 3282 PLTSMPVSTTTVASSETSTLSTTPADT-STPVTTYSQASSSPPIADGTSMPTSTYSEGST 3340
Query: 947 AVAGFSPEWAALAITVPITEEDG-----TPEGPVTPATT-VHAPEEPDTA---AVRVSTP 997
+ S T P+ + TP TP TT A P TA ++ S+P
Sbjct: 3341 PLTNMSFS------TTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSP 3394
Query: 998 EEPASPAAAVPTPEEP----------TSP------------AAAVPTPEEPTS-PAAAVP 1034
E +P A++P P T+P A++ PT E TS P +
Sbjct: 3395 SEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTS 3454
Query: 1035 PPEEPTS--PAAAVPTPEEPTSPAAAVP----TPEEPTSPAAAVPTPEE----PTSPAAA 1084
P S P + P S + P TP +SP + PT E PTS A
Sbjct: 3455 EGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGE 3514
Query: 1085 VPTPEEPTSPAAAVPTPEEPTSPAAAVP---------TPEEPASPAAA------VPTPEE 1129
TP P + P S + P + + +SPA + TP E
Sbjct: 3515 GSTPLT-NMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSE 3573
Query: 1130 ----------------------PASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPE 1167
P++P+ TP + + + PTP E + + + TP
Sbjct: 3574 GSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVIT--LPMSTPS 3631
Query: 1168 ESASPAAAVP--TPAESASFAAVVATLEEPTSP--------AASVPTPAAMVATLEEFTS 1217
E ++P +P T + + S A +TL TS ++S TP T+ +T
Sbjct: 3632 EVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPEG--TTMPIWTP 3689
Query: 1218 PAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTP 1277
S P + P S V++ E T +V T T+S A+ + L S SV P
Sbjct: 3690 SEGSTPLTTMPVS-TTRVTSSEGSTLSTPSVVTSTPVTTSTEAISSSATLDSTTMSVSMP 3748
Query: 1278 EEPASPAAAVSNLEEPASPAAAVPTPEVAAI------PAASVPTPEVPAIPAAAVPPMEE 1331
E ++ + P + TP + ++ AS + + PM
Sbjct: 3749 MEISTLGTTILVSTTPVTRFPESSTPSIPSVYTSMSMTTASEGSSSPTTLEGTTTMPMST 3808
Query: 1332 ------------VSPIGVPFLGVSAHTDSVPISEEGTPVLEEASSTGMWIKEDLDSLVFG 1379
+SPI V A T S P + TP+L + I ++ ++
Sbjct: 3809 TSERSTLLTTVLISPISV-MSPSEASTLSTPPGDTSTPLLTSTKAGSFSIPAEVTTIRIS 3867
Query: 1380 IKEVTSTVL 1388
I ST L
Sbjct: 3868 ITSERSTPL 3876
Score = 85.1 bits (209), Expect = 4e-16
Identities = 118/553 (21%), Positives = 209/553 (37%), Gaps = 39/553 (7%)
Query: 819 NTEPVLEEWIPV-LQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVP 877
N+ P E I + + PS + T+ ++ E GT+ + +P T V+ +
Sbjct: 3614 NSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTA-STLPVDTSTPVITSTQ- 3671
Query: 878 FPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVT--VSVPEGTAAVAAVSSPEETAPA 935
+ +S V+ E T + P + P T VS T++ + S +
Sbjct: 3672 ------VSSSPVTPEG---TTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTS 3722
Query: 936 VAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVS 995
+ E +S+ A ++++ + I+ T TP T P +V S
Sbjct: 3723 TPVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVYTS 3782
Query: 996 TPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSP--AAAVPTPEEPT 1053
AS ++ PT E T+ T E T + P SP A+ + TP T
Sbjct: 3783 MSMTTASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLSTPPGDT 3842
Query: 1054 SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTS-PAAAVP 1112
S TP ++ A + P E T+ ++ T E T + + PTS P A++
Sbjct: 3843 S------TPLLTSTKAGSFSIPAEVTTIRISI-TSERSTPLTTLLVSTTLPTSFPGASIA 3895
Query: 1113 TPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASP 1172
+ +P T P++ A+ PT + +V T + + +P+ ++S
Sbjct: 3896 S-----TPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSST 3950
Query: 1173 AAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLA 1232
A P + S + +T E +P+ S + +T +EFT+PA T+ P +
Sbjct: 3951 ADVFPATTGAVSTPVITST--ELNTPSTSSSSTTTSFSTTKEFTTPAM---TTAAPLTYV 4005
Query: 1233 AAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTP-EEPASPAAAVSNLE 1291
+ P P + + T S+ +A TP +S TP E + P+ S+
Sbjct: 4006 TMSTAPSTPRTTSRGCTT---SASTLSATSTPHTSTSVTTRPVTPSSESSRPSTITSHTI 4062
Query: 1292 EPASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPMEEVSPIGVPFLGVSAHTDSVPI 1351
P P A TP + + +V V + P S V V +T ++
Sbjct: 4063 PPTFPPAHSSTPPTTSASSTTVNPEAVTTMTTRTKPSTRTTSFPTVTTTAVPTNT-TIKS 4121
Query: 1352 SEEGTPVLEEASS 1364
+ TP + ++
Sbjct: 4122 NPTSTPTVPRTTT 4134
>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
Length = 825
Score = 107 bits (267), Expect = 8e-23
Identities = 151/552 (27%), Positives = 203/552 (36%), Gaps = 71/552 (12%)
Query: 812 KQVTKAGNTEPVLEEWIPVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAV 871
K+V A EP E P +P P V++A A P P E T + P+ E T
Sbjct: 250 KKVASA-EIEPPSTEKFPAKIQP------PLVEEATAKAEPRPAEETHVQVQPSTEETPD 302
Query: 872 VAALVPFPHEDILV----ASIVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVS 927
A + V A L E SA E +V + +P +
Sbjct: 303 AEAATAVAENSVKVQPPPAEEAPLVEFPAEIQPPSAEESPSVELLAEILPPSAEESPSEE 362
Query: 928 SPEETAPAVAA-AITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGP--VTPATTVHA- 983
P E P A + + E + + S + A + + P+ E E P V P T
Sbjct: 363 PPAEILPPPAEKSPSVELLGEIRSPSAQKAPIEVQ-PLPAEGALEEAPAKVEPPTVEETL 421
Query: 984 -------PEEPDTAAVRVSTPEEPASPAAAVPTPEEPT---SPAAAVPTPEEPTSPA--- 1030
PEE A R E S A P E PT SP T EE ++
Sbjct: 422 ADVQPLLPEE----APREEARELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAEIQLL 477
Query: 1031 AAVPPPEEPTSPAAAVPTPEEPT---------SPAAAVPTPEEPTSPA---AAVPTPEEP 1078
AA PP + T A P EE + SP A T EE ++ AA+ P +
Sbjct: 478 AATEPPADETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPADE 537
Query: 1079 TSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVP 1138
T A P EE ++ A + P E P+ T EE ++ +
Sbjct: 538 TPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLA 597
Query: 1139 TPEEPAFPAPAV--PTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPT 1196
E A APA P P E A A V P EE+ PA P PAE A EE
Sbjct: 598 ATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEA--PAEVQPPPAEEAPAEVQPPPAEE-- 653
Query: 1197 SPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAA--AVSNPEEPTSPAAAVPTLEEP 1254
+PA P PA EE + P E PA + + A P E T A P ++
Sbjct: 654 APAEVQPPPA------EEAPAEVQPPPAEEAPAEVQSLPAEETPIEETLAAVHSPPADDV 707
Query: 1255 TSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAI---PAA 1311
+ A+V ++ S PA + T E P A+A SP + TPE A+ +
Sbjct: 708 PAEEASV---DKHSPPADLLLTEEFPIGEASA------EVSPPPSEQTPEDEALVENVST 758
Query: 1312 SVPTPEVPAIPA 1323
+P+V IPA
Sbjct: 759 EFQSPQVAGIPA 770
Score = 103 bits (257), Expect = 1e-21
Identities = 159/626 (25%), Positives = 224/626 (35%), Gaps = 84/626 (13%)
Query: 778 ETVNDTK-----PELNVASSEGGEMERRDSDSFLNIFPEKQVTKAGNTEPVLEEWIPVLQ 832
E+V D + P + + + R + +NI P ++V K T E I V+
Sbjct: 110 ESVQDVEIPPNIPSVQLKMDRSQQTSRTGYWTMMNIPPVEKVDKEQQTY-FSESEIVVIS 168
Query: 833 RPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLE 892
RP +++ + +DAL + I A PE + ++I S S
Sbjct: 169 RPD-SSSTKSKEDAL-----KHKSSGKIFASEHPEFQPATNSNEEIGQKNI---SRTSFT 219
Query: 893 EEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFS 952
+E V + VTV V + +AV V+S E P S
Sbjct: 220 QETKKGPPVLLEDELR-EEVTVPVVQEGSAVKKVASAEIEPP-----------------S 261
Query: 953 PEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTA--------------AVRVSTPE 998
E I P+ EE T + PA H +P T +V+V P
Sbjct: 262 TEKFPAKIQPPLVEE-ATAKAEPRPAEETHVQVQPSTEETPDAEAATAVAENSVKVQPP- 319
Query: 999 EPASPAAAVPTPEEPTSPAA----AVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTS 1054
PA A V P E P+A +V E P+A P EEP PA +P P E +
Sbjct: 320 -PAEEAPLVEFPAEIQPPSAEESPSVELLAEILPPSAEESPSEEP--PAEILPPPAEKSP 376
Query: 1055 PA---AAVPTPEEPTSPAAAVPTPEEPT---SPAAAVPTPEEPTSPAAAVPTPEEPTSPA 1108
+ +P +P P P E +PA P E T PEE
Sbjct: 377 SVELLGEIRSPSAQKAPIEVQPLPAEGALEEAPAKVEPPTVEETLADVQPLLPEEAPREE 436
Query: 1109 A-------AVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAV 1161
A A+ TP E A P P+E + A+ A PA TP E+ S
Sbjct: 437 ARELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLS 496
Query: 1162 AVPTPEES----ASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTS 1217
+ EE+ SP A T E+++ ++A +E P TPA + L E TS
Sbjct: 497 EETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPADE-----TPAEAQSPLSEETS 551
Query: 1218 PAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTP 1277
+ + P++ ++ P + T E S+A +L E S+ A
Sbjct: 552 AEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQ 611
Query: 1278 EEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPMEEVSPIGV 1337
PA A A PA A A P A A V P PA PP E +P V
Sbjct: 612 PPPAEEAPAEVQ-PPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEV 670
Query: 1338 ---PFLGVSAHTDSVPISEEGTPVLE 1360
P A S+P E TP+ E
Sbjct: 671 QPPPAEEAPAEVQSLPAEE--TPIEE 694
>gi|238624188 diffuse panbronchiolitis critical region 1 protein [Homo
sapiens]
Length = 1393
Score = 105 bits (263), Expect = 2e-22
Identities = 140/549 (25%), Positives = 194/549 (35%), Gaps = 63/549 (11%)
Query: 819 NTEPVLEEWIPVLQRPSRTAAVPTVKDALDAALPSP---EEGTSIAAVPAPEGTAVVAAL 875
NT P E +R + P+ + + +P E+ T A P G
Sbjct: 532 NTTPSPAEPTENRERTANEKTTPSPAEPTENGDRTPLANEKTTPSLAEPTENGQRT---- 587
Query: 876 VPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPA 935
PF +E +S E E+ T A PA E TA E T P+
Sbjct: 588 -PFANEKTTSSSAEPTEHEERTPLANE--NTTPSPAEPTENRERTAN-------ENTTPS 637
Query: 936 VAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVS 995
A M+A + A T + T P P T + P S
Sbjct: 638 PAGPTENREMTANEKTTLFPAEPTENRERTANEKTTSSPAEP--TENGQRTPFANEKTTS 695
Query: 996 TPEEPASPAAAVPTPEEPTSPAAAVPTPE-EPTSPAAAVPPPEEPTSPAAAVPTPEEPTS 1054
+ EP P E T+ + A PT E T+ P P EPT T E T+
Sbjct: 696 SSAEPTEHGERTPLANENTTLSPAEPTENRERTANEKTTPFPAEPTENRER--TANENTT 753
Query: 1055 PAAAVPTPEEPTSPAA---AVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAV 1111
P+ A PT +P A P+ EPT P E T+ ++A PT +P A
Sbjct: 754 PSPAQPTENGDRTPLANEKTTPSLAEPTENGKRTPFANEKTTSSSAEPTEHAERTPLANE 813
Query: 1112 PTPEEPASPA------AAVPTPEEPASPAA-AVPTPEEPAFPAPAVPTPE------ESAS 1158
T PA P A T + PA P T E P PA PT E+ +
Sbjct: 814 NTTSSPAEPTENRERTANEKTTQFPAEPTENRESTANEKTTPFPAEPTENREWTANENTT 873
Query: 1159 AAVAVPTPEESASPAAAVPT---PAESASFAAVVATLEEPTSPAASVPTPAAMVATL-EE 1214
+ A PT E +P A T PAE E T+P+++ PT L E
Sbjct: 874 LSPAEPTEHEEMTPLANEKTTLSPAEPTENGERTPFTNEKTTPSSAEPTEHGERTPLANE 933
Query: 1215 FTSPAASVPTSE-EPASLAAAVSNPEEPT-----------SPAAAVPTL---------EE 1253
T+P+ + PT E + A +P +PT +P++A PT E
Sbjct: 934 ITTPSRAEPTEHGERIANEKATPSPAKPTEHGETTVNEDTTPSSAEPTENGERTPLANEN 993
Query: 1254 PTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASV 1313
T+S E ++ + P+P EP + E P+ A PT P+A+
Sbjct: 994 TTTSPTESTEHGERTANEKTTPSPAEPTEHGERTPSANEKTIPSPAKPTEHEEMTPSANE 1053
Query: 1314 PTPEVPAIP 1322
T P P
Sbjct: 1054 NTTPSPVKP 1062
Score = 105 bits (261), Expect = 4e-22
Identities = 140/589 (23%), Positives = 209/589 (35%), Gaps = 72/589 (12%)
Query: 796 EMERRDSDSFLNIFPEKQVTKAGNTEPVLEEWIPVLQRPSRTAAVPTV---KDALDAALP 852
E + DS + +K +TK T ++E I + +++ A PT + A + P
Sbjct: 244 EESEKTEDSRTTVASDKLLTK---TTKNIQETISANEL-TQSLAEPTEHGGRTANENNTP 299
Query: 853 SPEEGTSIAAVPAPEGTAVVAA-------------LVPFP-----HEDILVASIVSLEEE 894
SP E T A E T + A PFP + ++ +L
Sbjct: 300 SPAEPTENRERTANENTTLSPAEPIENRERTANENTAPFPAGPTENREMTANENTTLFPA 359
Query: 895 DVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPE 954
+ T T P+ G ++P P T S E
Sbjct: 360 EPTEHGERTANENTTPSPAEPTEHGERTANENTTPSPAEPTEHGERTPFANDKTTSSSAE 419
Query: 955 WAALAITVPITEEDGTPEGPVTPAT----TVHAPEEPDTAAV---RVSTPEEPASPAAAV 1007
P+ E+ TP P P T + P A R +T E + +
Sbjct: 420 STEHGERTPLANENTTPS-PAEPTENRERTANENTTPSPAGPTENRETTANEKTTLSPVE 478
Query: 1008 PTPE-EPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAA---AVPTPE 1063
PT E T+ P+P EPT P E T+ ++A PT +P A P+P
Sbjct: 479 PTENRETTANEKTTPSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTPSPA 538
Query: 1064 EPT------SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPT--------PEEPTSPAA 1109
EPT + P+P EPT P E T+P+ A PT E T+ ++
Sbjct: 539 EPTENRERTANEKTTPSPAEPTENGDRTPLANEKTTPSLAEPTENGQRTPFANEKTTSSS 598
Query: 1110 AVPTPEEPASPAAAVPTPEEPASPAA-AVPTPEEPAFPAPAVP------TPEESASAAVA 1162
A PT E +P A T PA P T E P+PA P T E + A
Sbjct: 599 AEPTEHEERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENREMTANEKTTLFPA 658
Query: 1163 VPTP-EESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATL-EEFTSPAA 1220
PT E + +PAE E T+ +++ PT L E T+ +
Sbjct: 659 EPTENRERTANEKTTSSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTLSP 718
Query: 1221 SVPT-------SEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAAS 1273
+ PT +E+ A + E T+ P+ +PT + E ++P+ +
Sbjct: 719 AEPTENRERTANEKTTPFPAEPTENRERTANENTTPSPAQPTENGDRTPLANEKTTPSLA 778
Query: 1274 VPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIP 1322
PT +P A E + ++A PT P A+ T PA P
Sbjct: 779 EPTENGKRTPFA-----NEKTTSSSAEPTEHAERTPLANENTTSSPAEP 822
Score = 102 bits (253), Expect = 3e-21
Identities = 141/550 (25%), Positives = 193/550 (35%), Gaps = 105/550 (19%)
Query: 901 VSAPERATV-PAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALA 959
++A E+ T+ PA E TA SSP E T+ G F+ E +
Sbjct: 647 MTANEKTTLFPAEPTENRERTANEKTTSSPAEP--------TENGQRTP--FANEKTTSS 696
Query: 960 ITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPE-EPTSPAA 1018
P + TP + T +P EP R T E +P A PT E T+
Sbjct: 697 SAEPTEHGERTP---LANENTTLSPAEPTENRER--TANEKTTPFPAEPTENRERTANEN 751
Query: 1019 AVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPE----------------EPTSPAAAVPTP 1062
P+P +PT P E T+P+ A PT EPT A P
Sbjct: 752 TTPSPAQPTENGDRTPLANEKTTPSLAEPTENGKRTPFANEKTTSSSAEPTEHAERTPLA 811
Query: 1063 EEPTSPAAAVPT--------------PEEPTSPAAAVPTPEEPTSPAAAVPTPE------ 1102
E T+ + A PT P EPT + T E T+P A PT
Sbjct: 812 NENTTSSPAEPTENRERTANEKTTQFPAEPTENRES--TANEKTTPFPAEPTENREWTAN 869
Query: 1103 EPTSPAAAVPTPEEPASPAAAVPT---PEEPASPAAAVPTPEEPAFPAPAVPTPE-ESAS 1158
E T+ + A PT E +P A T P EP P E P+ A PT E
Sbjct: 870 ENTTLSPAEPTEHEEMTPLANEKTTLSPAEPTENGERTPFTNEKTTPSSAEPTEHGERTP 929
Query: 1159 AAVAVPTPE--------ESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTP---AA 1207
A + TP E + A P+PA+ T+ E T+P+++ PT
Sbjct: 930 LANEITTPSRAEPTEHGERIANEKATPSPAKPTEHGET--TVNEDTTPSSAEPTENGERT 987
Query: 1208 MVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEEL 1267
+A TSP S E A+ S P EPT P+ E T + A T E
Sbjct: 988 PLANENTTTSPTESTEHGERTANEKTTPS-PAEPTEHGERTPSANEKTIPSPAKPTEHEE 1046
Query: 1268 SSPAASVPT------------------------PEEPASPAAAVSNLEEPASPAAAVPT- 1302
+P+A+ T PE P A ++ E +P+ A PT
Sbjct: 1047 MTPSANENTTPSPVKPTEHGEKTTLANEKITLSPEGPTEHGAKTTSANEKITPSLAKPTE 1106
Query: 1303 -------PEVAAIPAASVPTPEVPAIPAAAVPPMEEVSPIGVPFLGVSAHTDSVPISEEG 1355
P +A+ T +A V PI AH ++E+
Sbjct: 1107 HGERTTSPNDKITSSAAESTEHRDRATSANVITPAPAEPIKHAKRTTLAHEKMTQVTEKS 1166
Query: 1356 TPVLEEASST 1365
T E+ +ST
Sbjct: 1167 TEHPEKTTST 1176
Score = 84.3 bits (207), Expect = 7e-16
Identities = 92/351 (26%), Positives = 133/351 (37%), Gaps = 52/351 (14%)
Query: 963 PITEEDGTPEG----------PVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPE- 1011
P T E TP P+ T + EP R++ E A+P+ A PT
Sbjct: 908 PFTNEKTTPSSAEPTEHGERTPLANEITTPSRAEPTEHGERIAN--EKATPSPAKPTEHG 965
Query: 1012 -----EPTSPAAAVPTPEEPTSPAA----AVPPPE-----EPTSPAAAVPTPEEPTSPAA 1057
E T+P++A PT +P A P E E T+ P+P EPT
Sbjct: 966 ETTVNEDTTPSSAEPTENGERTPLANENTTTSPTESTEHGERTANEKTTPSPAEPTEHGE 1025
Query: 1058 AVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPE-EPTSPAAAVPT--P 1114
P+ E T P+ A PT E +P+A E T+P+ PT E T+ A T P
Sbjct: 1026 RTPSANEKTIPSPAKPTEHEEMTPSA-----NENTTPSPVKPTEHGEKTTLANEKITLSP 1080
Query: 1115 EEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAA 1174
E P A + E +P+ A PT + P + ++SAA + + + S
Sbjct: 1081 EGPTEHGAKTTSANEKITPSLAKPTEHGERTTS---PNDKITSSAAESTEHRDRATSANV 1137
Query: 1175 AVPTPAESASFAAVVATLEEPTSPAASVPT--PAAMVATLEEFTSPAASVPTSEEPASLA 1232
P PAE A E + T P +T E+ T+ PT ++
Sbjct: 1138 ITPAPAEPIKHAKRTTLAHEKMTQVTEKSTEHPEKTTSTTEK-TTRTPEKPTLYSEKTIC 1196
Query: 1233 AAVSNPEEPTSPAAAVPTLEEPTSSAA-AVLTPEELSSPAASVPTPEEPAS 1282
N P E+PT + LT E + +P S PE+ A+
Sbjct: 1197 TKGKN----------TPVPEKPTENLGNTTLTTETIKAPVKSTENPEKTAA 1237
Score = 79.0 bits (193), Expect = 3e-14
Identities = 90/362 (24%), Positives = 123/362 (33%), Gaps = 31/362 (8%)
Query: 976 TPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAV-- 1033
T T PEE + +T +E S + EPT
Sbjct: 235 TTYKTTGTPEESEKTEDSRTTVASDKLLTKTTKNIQETISANELTQSLAEPTEHGGRTAN 294
Query: 1034 ----PPPEEPTSPAAAVPTPEEPTSPAAAVP----TPEEPTSPAAAVPTPE-EPTSPAAA 1084
P P EPT SPA + T E T+P A PT E T+
Sbjct: 295 ENNTPSPAEPTENRERTANENTTLSPAEPIENRERTANENTAPFPAGPTENREMTANENT 354
Query: 1085 VPTPEEPTSPAAAVPTPEEPTSPAAAVPTPE-EPASPAAAVPTPEEPASPAAAVPTPEEP 1143
P EPT T E T+P+ A PT E + P+P EP P +
Sbjct: 355 TLFPAEPTEHGER--TANENTTPSPAEPTEHGERTANENTTPSPAEPTEHGERTPFANDK 412
Query: 1144 AFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVP 1203
+ A ES P E+ +P+ A PT T E T+P+ + P
Sbjct: 413 TTSSSA-----ESTEHGERTPLANENTTPSPAEPTENRER-------TANENTTPSPAGP 460
Query: 1204 TPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLT 1263
T E+ T + E + +P EPT P E T+S++A T
Sbjct: 461 TENRETTANEKTTLSPVEPTENRETTANEKTTPSPAEPTENGQRTPFANEKTTSSSAEPT 520
Query: 1264 PEELSSPAA---SVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPA 1320
+P A + P+P EP +N E +P+ A PT P A+ T A
Sbjct: 521 EHGERTPLANENTTPSPAEPTENRERTAN--EKTTPSPAEPTENGDRTPLANEKTTPSLA 578
Query: 1321 IP 1322
P
Sbjct: 579 EP 580
Score = 34.7 bits (78), Expect = 0.67
Identities = 62/302 (20%), Positives = 92/302 (30%), Gaps = 19/302 (6%)
Query: 1013 PTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAV 1072
P +P P + + PPE P S + + + ++PT + +
Sbjct: 49 PLTPGLVYSIPFDHIVLHSGQRPPELPKS--TEIHEQKRHCNTTRHSKPTDKPTGNSKTI 106
Query: 1073 PTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTS--PAAAVPTPEEPASPAAAVPTPEEP 1130
+ T A PT EE +S P S PA + T +E A P P+
Sbjct: 107 DH-KSSTDNHEAPPTSEENSSNQGKDPMIRNQRSVDPADSTTTHKESAGKKHITPAPKSK 165
Query: 1131 ASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVA 1190
+ + + P E + + + + S S + S +
Sbjct: 166 INCRKSTTGKSTVTRKSDKTGRPLEKSMSTL----DKTSTSSHKTTTSFHNSGNSQTKQK 221
Query: 1191 TLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPT 1250
+ P A+ T T EE S T L N +E S +
Sbjct: 222 STSFPEKITAASKTTYKTTGTPEESEKTEDSRTTVASDKLLTKTTKNIQETISANELTQS 281
Query: 1251 LEEPTSSAAAVLTPEELSSPAASVPTPEEPA------SPAAAVSNLE----EPASPAAAV 1300
L EPT SPA E A SPA + N E E +P A
Sbjct: 282 LAEPTEHGGRTANENNTPSPAEPTENRERTANENTTLSPAEPIENRERTANENTAPFPAG 341
Query: 1301 PT 1302
PT
Sbjct: 342 PT 343
>gi|239740773 PREDICTED: similar to diffuse panbronchiolitis critical
region 1 [Homo sapiens]
Length = 1400
Score = 104 bits (260), Expect = 5e-22
Identities = 140/589 (23%), Positives = 209/589 (35%), Gaps = 72/589 (12%)
Query: 796 EMERRDSDSFLNIFPEKQVTKAGNTEPVLEEWIPVLQRPSRTAAVPTV---KDALDAALP 852
E + DS + +K +TK T ++E I + +++ A PT + A + P
Sbjct: 306 EESEKTEDSRTTVASDKLLTK---TTKNIQETISANEL-TQSLAEPTEHGGRTANENNTP 361
Query: 853 SPEEGTSIAAVPAPEGTAVVAA-------------LVPFP-----HEDILVASIVSLEEE 894
SP E T A E T + A PFP + ++ +L
Sbjct: 362 SPAEPTENRERTANENTTLSPAEPTENRERTANENTAPFPAGPTENREMTANENTTLFPA 421
Query: 895 DVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPE 954
+ T T P+ G ++P P T S E
Sbjct: 422 EPTEHGERTANENTTPSPAEPTEHGERTANENTTPSPAEPTEHGERTPFANDKTTSSSAE 481
Query: 955 WAALAITVPITEEDGTPEGPVTPAT----TVHAPEEPDTAAV---RVSTPEEPASPAAAV 1007
P+ E+ TP P P T + P A R +T E + +
Sbjct: 482 STEHGERTPLANENTTPS-PAEPTENRERTANENTTPSPAGPTENRETTANEKTTLSPVE 540
Query: 1008 PTPE-EPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAA---AVPTPE 1063
PT E T+ P+P EPT P E T+ ++A PT +P A P+P
Sbjct: 541 PTENRETTANEKTTPSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTPSPA 600
Query: 1064 EPT------SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPT--------PEEPTSPAA 1109
EPT + P+P EPT P E T+P+ A PT E T+ ++
Sbjct: 601 EPTENRERTANEKTTPSPAEPTENGDRTPLANEKTTPSLAEPTENGQRTPFANEKTTSSS 660
Query: 1110 AVPTPEEPASPAAAVPTPEEPASPAA-AVPTPEEPAFPAPAVP------TPEESASAAVA 1162
A PT E +P A T PA P T E P+PA P T E + A
Sbjct: 661 AEPTEHEERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENREMTANEKTTLFPA 720
Query: 1163 VPTP-EESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATL-EEFTSPAA 1220
PT E + +PAE E T+ +++ PT L E T+ +
Sbjct: 721 EPTENRERTANEKTTSSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTLSP 780
Query: 1221 SVPT-------SEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAAS 1273
+ PT +E+ A + E T+ P+ +PT + E ++P+ +
Sbjct: 781 AGPTENRERTANEKTTPFPAEPTENRERTANENTTPSPAQPTENGDRTPLANEKTTPSLA 840
Query: 1274 VPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIP 1322
PT +P A E + ++A PT P A+ T PA P
Sbjct: 841 EPTENGKRTPFA-----NEKTTSSSAEPTEHAERTPLANENTTSSPAEP 884
Score = 86.7 bits (213), Expect = 1e-16
Identities = 105/420 (25%), Positives = 145/420 (34%), Gaps = 36/420 (8%)
Query: 963 PITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPT 1022
P+ E TP T + P S+ EP P E T+P+ A PT
Sbjct: 629 PLANEKTTPS---LAEPTENGQRTPFANEKTTSSSAEPTEHEERTPLANENTTPSPAEPT 685
Query: 1023 P-EEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTP-EEPTSPAAAVPTPEEPTS 1080
E T+ P P PT T E T+ A PT E T+ +P EPT
Sbjct: 686 ENRERTANENTTPSPAGPTENREM--TANEKTTLFPAEPTENRERTANEKTTSSPAEPTE 743
Query: 1081 PAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAA-AVPTPEEPASPAAAVP- 1138
P E T+ ++A PT +P A T PA P T E +P A P
Sbjct: 744 NGQRTPFANEKTTSSSAEPTEHGERTPLANENTTLSPAGPTENRERTANEKTTPFPAEPT 803
Query: 1139 -----TPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTP-AESASFAAVVATL 1192
T E P+PA PT + P E +P+ A PT + FA
Sbjct: 804 ENRERTANENTTPSPAQPTENGDRT-----PLANEKTTPSLAEPTENGKRTPFAN----- 853
Query: 1193 EEPTSPAASVPTPAAMVATLEEFTSPAASVPT-------SEEPASLAAAVSNPEEPTSPA 1245
E+ TS +A A E T+ + + PT +E+ A + E T+
Sbjct: 854 EKTTSSSAEPTEHAERTPLANENTTSSPAEPTENRERTANEKTTQFPAEPTENRESTANE 913
Query: 1246 AAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEV 1305
P EPT + SPA PT E +P NL+ P + P+
Sbjct: 914 KTTPFPAEPTENREWTANENTTLSPAE--PTEHEEMTPLMVDENLQAPFRQGSCAERPKD 971
Query: 1306 AAIPAASVPTPEVPAIPAAAVPPMEEVSPIGVPFLGVSAHTDSVPISEEGTPVLEEASST 1365
AS E + A+ + +S S+ + +S PV A T
Sbjct: 972 ICATVASTTGSE--SSTASEIITSSTMSVSATASSTASSTASEITMSSAAIPVSSTAYET 1029
Score = 79.0 bits (193), Expect = 3e-14
Identities = 91/356 (25%), Positives = 128/356 (35%), Gaps = 19/356 (5%)
Query: 976 TPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPP 1035
T T PEE + +T +E S + EPT
Sbjct: 297 TTYKTTGTPEESEKTEDSRTTVASDKLLTKTTKNIQETISANELTQSLAEPTEHGGRTA- 355
Query: 1036 PEEPTSPAAAVPTPE-EPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPE-EPTS 1093
E +P+ A PT E T+ +P EPT T E T+P A PT E T+
Sbjct: 356 -NENNTPSPAEPTENRERTANENTTLSPAEPTENRER--TANENTAPFPAGPTENREMTA 412
Query: 1094 PAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPE-EPASPAAAVPTPEEPAFPAPAVPT 1152
P EPT T E +P+ A PT E + P+P EP P
Sbjct: 413 NENTTLFPAEPTEHGER--TANENTTPSPAEPTEHGERTANENTTPSPAEPTEHGERTPF 470
Query: 1153 PEESASAAVAVPTPEESASPAA---AVPTPAESASFAAVVATLEEPTSPAASVPTPAAMV 1209
+ +++ A T +P A P+PAE T E T+P+ + PT
Sbjct: 471 ANDKTTSSSAESTEHGERTPLANENTTPSPAEPTENRE--RTANENTTPSPAGPTENRET 528
Query: 1210 ATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSS 1269
E+ T + E + +P EPT P E T+S++A T +
Sbjct: 529 TANEKTTLSPVEPTENRETTANEKTTPSPAEPTENGQRTPFANEKTTSSSAEPTEHGERT 588
Query: 1270 PAA---SVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIP 1322
P A + P+P EP +N E +P+ A PT P A+ T A P
Sbjct: 589 PLANENTTPSPAEPTENRERTAN--EKTTPSPAEPTENGDRTPLANEKTTPSLAEP 642
Score = 65.1 bits (157), Expect = 5e-10
Identities = 153/693 (22%), Positives = 238/693 (34%), Gaps = 106/693 (15%)
Query: 694 ENNSLTSMGNVVTCELSVEKVCDEDGEAKELDYQATLLEDQAPAHFHRN--------FPE 745
EN T N T S E E GE L + T L P FP
Sbjct: 743 ENGQRTPFANEKTTSSSAEPT--EHGERTPLANENTTLSPAGPTENRERTANEKTTPFPA 800
Query: 746 QVFQDLQRKSPESEILSLHLLVEELRLNPDGVETVND-TKPEL---------------NV 789
+ ++ +R + E+ S E N D N+ T P L
Sbjct: 801 EPTENRERTANENTTPSPAQPTE----NGDRTPLANEKTTPSLAEPTENGKRTPFANEKT 856
Query: 790 ASSEGGEMERRDSDSFLNIFPEKQVTKAGNTEPVLEEWIPVLQRPSRTAAVPTVK---DA 846
SS E + N + T + EP ++ ++ A PT A
Sbjct: 857 TSSSAEPTEHAERTPLAN-----ENTTSSPAEPTENRERTANEKTTQFPAEPTENRESTA 911
Query: 847 LDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASI------------VSLEEE 894
+ P P E T A E T + A P HE++ + + +
Sbjct: 912 NEKTTPFPAEPTENREWTANENTTLSPA-EPTEHEEMTPLMVDENLQAPFRQGSCAERPK 970
Query: 895 DV--TAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFS 952
D+ T A+ + E +T + S T +V+A +S TA + A+ IT +A+ S
Sbjct: 971 DICATVASTTGSESSTASEIITS---STMSVSATAS--STASSTASEITMSS-AAIPVSS 1024
Query: 953 PEWAAL----AITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVP 1008
+ + A++ P+T E + T + +V + + A
Sbjct: 1025 TAYETIRFSTAVSEPVTASILALESTLAFTTVSNTTTSSTVTSVPTTASTSGSKNTTACE 1084
Query: 1009 TPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVP---TPEEP 1065
T+ AA + + S +V E A PT S +A VP T
Sbjct: 1085 ATMSETTIAAITASEDTTVSTQTSVIAAESVPHTATKTPTDTTTASVSATVPKNNTLSVI 1144
Query: 1066 TSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVP 1125
TS + P T A+ T TS ++PT V T + + +P
Sbjct: 1145 TSTPSTAPNTASKTMTTASKTTT---TSTITSLPT---------TVFTTTSKITAGSEIP 1192
Query: 1126 TPEEPASPAAAVPTPEE----PAFPAPAVPTPEESASAAVAVPTPEESAS-----PAAAV 1176
T S A+ T + P+ A PTP E+ +A+V T + ++V
Sbjct: 1193 TASTTDSATTAISTKASGTTVESAPSTAPPTPAETTTASVPTTTSTTGSENTGHHTVSSV 1252
Query: 1177 PTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPA--SLAAA 1234
PT V AT E S S T A+ AT E T+ ++ T E A S A
Sbjct: 1253 PT--------TVFATASE--SSTGSETTRASTSAT-EVTTAMTTAMTTGSETAVVSTKAP 1301
Query: 1235 VSNPEEPTSPAAAVP---TLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLE 1291
V+ + S A +P T +++A+ L + S A SVPT + + + +
Sbjct: 1302 VTTTQSGFSTATVMPAKTTTASVSTTASTTLYQNTIDSVAKSVPTMDSTIASKSTTLSKI 1361
Query: 1292 EPASPAAAVPTPEV---AAIPAASVPTPEVPAI 1321
A + PE + I AS+ T A+
Sbjct: 1362 VSVPTAVFIKAPETTTGSEITLASIITSGTTAV 1394
Score = 37.0 bits (84), Expect = 0.14
Identities = 81/421 (19%), Positives = 128/421 (30%), Gaps = 42/421 (9%)
Query: 944 GMSAVAGFSP--------EWAALAITVPITEED-------------------GTPEGPVT 976
G+ A+AG SP +WA + IT+ + G G VT
Sbjct: 10 GLQALAGPSPKPQKDSVSDWAIVLITLTLVAAIVSLMYGIKKACQFRREMSLGCGCGSVT 69
Query: 977 PATTVHAPEEPD---TAAVRVSTPEEPASPAAAVPTPEE--PTSPAAAVPTPEEPTSPAA 1031
P ++ H E + ++ +T + + T + P +P P + +
Sbjct: 70 PYSSHHEGEAASQRYSCQMKGATTFQEYQKTGELSTSDHIFPLTPGLVYSIPFDHIVLHS 129
Query: 1032 AVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEP 1091
PPE P S + + + ++PT + + + T A PT EE
Sbjct: 130 GQRPPELPKS--TEIHEQKRHCNTTRHSKPTDKPTGNSKTIDH-KSSTDNHEAPPTSEEN 186
Query: 1092 TSPAAAVPTPEEPTS--PAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPA 1149
+S P S PA + T +E A P P+ + + +
Sbjct: 187 SSNQGKDPMIRNQRSVDPADSTTTHKESAGKKHITPAPKSKINCRKSTTGKSTVTRKSDK 246
Query: 1150 VPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMV 1209
P E + + + + S S + S + + P A+ T
Sbjct: 247 TGRPLEKSMSTL----DKTSTSSHKTTTSFHNSGNSQTKQKSTSFPEKITAASKTTYKTT 302
Query: 1210 ATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSS 1269
T EE S T L N +E S +L EPT S
Sbjct: 303 GTPEESEKTEDSRTTVASDKLLTKTTKNIQETISANELTQSLAEPTEHGGRTANENNTPS 362
Query: 1270 PAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPM 1329
PA E A+ +S EP A PA E+ A + P
Sbjct: 363 PAEPTENRERTANENTTLSP-AEPTENRERTANENTAPFPAGPTENREMTANENTTLFPA 421
Query: 1330 E 1330
E
Sbjct: 422 E 422
>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
Length = 2217
Score = 104 bits (260), Expect = 5e-22
Identities = 130/462 (28%), Positives = 183/462 (39%), Gaps = 70/462 (15%)
Query: 945 MSAVAGFSPEWAALAITVPITEEDGTPEGPVTPAT--TVHAPEEPDTA-AVRVSTPEEPA 1001
+ ++A +P A + P++E GPV P + ++ A ++P A + V + PA
Sbjct: 637 LGSLADAAPSPAQCVCSPPVSE------GPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPA 690
Query: 1002 SPAAA---VPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPE----EPTS 1054
P + P P +P P+ PT P PP ++P A P P+ +P
Sbjct: 691 CPPSLQQHFPDPAMSFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVV 750
Query: 1055 PAAAVPTPEEP-TSPAAAV---------PTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEP 1104
P VP P +PA+ V P+ P P A VP P P V P P
Sbjct: 751 PLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVP----PQMPPIPVVPPITP 806
Query: 1105 TSPAAAVPTPEEPASPAAAVP--TPEEPASPAAAVPT------PEEPAFPAPAVPTPEES 1156
+ +P P P P A VP P + SPA +P+ P PA P AV P
Sbjct: 807 LAGIDGLP-PALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVKLP-HP 864
Query: 1157 ASAAVAVP----TPEESAS-PAAAVPTPAESA-SFAAVVATLE-EPTSPAA---SVPT-- 1204
A +A+P P A+ P AV P +A S + VA L +P PAA PT
Sbjct: 865 PGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDV 924
Query: 1205 PAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTP 1264
P + T++ + +P V P+ P +P +PT VL P
Sbjct: 925 PPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLP--PQPTRPPQPVLPP 982
Query: 1265 EELSSPAASV-PTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPA-----ASVPTPEV 1318
+ + P + P P P P +L E A+PAA + + PA + P V
Sbjct: 983 QPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTV 1042
Query: 1319 PAIPAAAV-PPMEEVSPIGVPFL---------GVSAHTDSVP 1350
P PAA + PP+ EV P L VSA SVP
Sbjct: 1043 PVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVP 1084
Score = 94.7 bits (234), Expect = 5e-19
Identities = 143/525 (27%), Positives = 194/525 (36%), Gaps = 90/525 (17%)
Query: 857 GTSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEEEDVTAAAV-----SAPERATVPA 911
G+ A P+P A P +L S+ SL AA S P A P+
Sbjct: 638 GSLADAAPSP---AQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPS 694
Query: 912 VTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVP--ITEEDG 969
+ P+ + A V P T T G A G P A +P + +
Sbjct: 695 LQQHFPDPAMSFAPVLPPPSTPMP-----TGPGQPAPPGQQPPPLAQPTPLPQVLAPQPV 749
Query: 970 TPEGPV--------TPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVP 1021
P PV PA+ V AP + + P+ P P A VP P P V
Sbjct: 750 VPLQPVPPHLPPYLAPASQVGAPAQLKP----LQMPQAPLQPLAQVP----PQMPPIPVV 801
Query: 1022 TPEEPTSPAAAVPP--PEEPTSPAAAVPTPEEPTSPAAAVPT------PEEPTSPAAAVP 1073
P P + +PP P+ PT+ VP P+ SPA +P+ P P P AV
Sbjct: 802 PPITPLAGIDGLPPALPDLPTATVPPVPPPQY-FSPAVILPSLAAPLPPASPALPLQAVK 860
Query: 1074 TPEEPTSPAAAVPTPEEPTSPAA------AVPTPEEPTSPAAAVPTPEEPASPAA---AV 1124
P P +P A P +PA A P + +A P +P PAA
Sbjct: 861 LPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMA 920
Query: 1125 PTPEEPASPAAAVP----TPEEPAFPAPAVPTPEESASAAVAVPT----PEESASPAAAV 1176
PT + P SP V TP +PA P P+ +P P + P V
Sbjct: 921 PT-DVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPV 979
Query: 1177 PTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSE----EPASLA 1232
P V+ P PA V P + L E +PAA+ P S+ PA A
Sbjct: 980 LPPQPMLPPQPVL-----PPQPALPV-RPEPLQPHLPEQAAPAAT-PGSQILLGHPAPYA 1032
Query: 1233 AAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPE--ELSSPAASVPTPEEPASPAAAVSNL 1290
V AA VPT+ P AAVL+P E+ PAA P+ P+S A +++
Sbjct: 1033 VDV---------AAQVPTVPVPP---AAVLSPPLPEVLLPAAPELLPQFPSSLATVSASV 1080
Query: 1291 EEPASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPMEEVSPI 1335
+ +VPT +P A+ P P P I + V P+
Sbjct: 1081 Q-------SVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEPV 1118
Score = 82.4 bits (202), Expect = 3e-15
Identities = 108/423 (25%), Positives = 152/423 (35%), Gaps = 83/423 (19%)
Query: 955 WAALAITVPITEED-GTPE---GPVTPA---TTVHA---------PEEPDTAAVRVSTPE 998
W AL P ++D G+P+ GP P T HA PEEP+ A + P
Sbjct: 547 WPALQ---PKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPE-ADQHLLPPT 602
Query: 999 EPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPP-PEEPTSPAAAVPTPEEPTSPAA 1057
P S + + + V + + + + + + SPA V +P P
Sbjct: 603 LPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVL 662
Query: 1058 AVPTP-----EEPTS----PAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPA 1108
P ++PT+ P +VP P P S P P +P P+ PT P
Sbjct: 663 PQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTGPG 722
Query: 1109 AAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPT--- 1165
P ++P P A PTP P P P P P P P + ++ V P
Sbjct: 723 QPAPPGQQP--PPLAQPTP----LPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLK 776
Query: 1166 ----PEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAAS 1221
P+ P A VP P P V P +A ++
Sbjct: 777 PLQMPQAPLQPLAQVP-----------------PQMPPIPVVPPITPLAGIDGLPPALPD 819
Query: 1222 VPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPA 1281
+PT+ P P + SPA +P+L AA L P + P +V P P
Sbjct: 820 LPTATVPP------VPPPQYFSPAVILPSL-------AAPLPPASPALPLQAVKLPHPPG 866
Query: 1282 SPAAAVSNLEEPASPAA----AVPTPEVAA--IPAASVPTPEVPAIPAAAVPPMEEVSPI 1335
+P A P +PA AV P VAA I +A P P PAA +++P
Sbjct: 867 APLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAA----FPQMAPT 922
Query: 1336 GVP 1338
VP
Sbjct: 923 DVP 925
Score = 69.3 bits (168), Expect = 2e-11
Identities = 99/396 (25%), Positives = 139/396 (35%), Gaps = 72/396 (18%)
Query: 829 PVLQRPSRTAAVPTVK--------DALDAALPSPEEGTSIAAVPAPE--GTAVV----AA 874
P+ Q P + +P V D L ALP T + VP P+ AV+ AA
Sbjct: 787 PLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTAT-VPPVPPPQYFSPAVILPSLAA 845
Query: 875 LVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAP 934
+P P L V L A ++ P R VP ++P + AV+ P A
Sbjct: 846 PLP-PASPALPLQAVKLPHPP--GAPLAMPCRTIVPNAPATIP-----LLAVAPPGVAAL 897
Query: 935 AVAAAITQ-EGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVR 993
++ +A+ Q G P+ A + P + H + +
Sbjct: 898 SIHSAVAQLPGQPVYPAAFPQMAPTDV----------------PPSPHHTVQNMRATPPQ 941
Query: 994 VSTPEEPASPAAAVPTPEEPTSPAAAVPT----PEEPTSPAAAVPPPEEPTSPAAAVPTP 1049
+ P +P P V P+ P +P P +P P + PP+ P A+P
Sbjct: 942 PALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVR 1001
Query: 1050 EEPTSP-----AAAVPTPEE--------PTSPAAAVPTPEEPTSPAAAVPTP-EEPTSPA 1095
EP P AA TP P + A P P PAA + P E PA
Sbjct: 1002 PEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLLPA 1061
Query: 1096 AAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEP--AFPAPAV--- 1150
A P+ P+S A ++ +VPT P A P P P A P P V
Sbjct: 1062 APELLPQFPSSLATV-------SASVQSVPTQTATLLPPANPPLPGGPGIASPCPTVQLT 1114
Query: 1151 --PTPEESASAAVAVPTPEESASPAAAVPTPAESAS 1184
P EE AS P+ S + T + S
Sbjct: 1115 VEPVQEEQASQDKPPGLPQSCESYGGSDVTSGKELS 1150
Score = 65.5 bits (158), Expect = 4e-10
Identities = 101/424 (23%), Positives = 160/424 (37%), Gaps = 34/424 (8%)
Query: 960 ITVPITEEDGTPEGPVT----PATTVHAPEEPDTAAVR--VSTPEEPASPAAA-VPTPEE 1012
I P+ E PE P + P +++ D+A + +S+ E+P+ A+ + +
Sbjct: 1314 IICPVAEHPA-PEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAG 1372
Query: 1013 PTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVP-TPEEPTSP-AA 1070
P++P A P P P+SP P + + +P P T+ A P TP+ TS
Sbjct: 1373 PSNPPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELET 1432
Query: 1071 AVPTPEEPTSPAAAVP--------TPEEPTSPAAAVPTPEEPTSPAAAVPTPEE-PASPA 1121
+ P E +P A P TP + P EP P A P+P PA
Sbjct: 1433 SQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPA 1492
Query: 1122 AAVPTPEEPAS-PAAAVPTPEEPAFP-APAVPTPEESASAAVAVPTPEESASPAAAVPTP 1179
P P PA+ A ++ T + P+ P P VP SA + P + + +
Sbjct: 1493 LGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSL 1552
Query: 1180 AESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPE 1239
E ++ PTS +AS TP + P SE A P+
Sbjct: 1553 DE--KLRTLLYQEHVPTS-SASAGTPVEVGDRDFTLEPLRGDQPRSEVCGGDLALPPVPK 1609
Query: 1240 EPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAA 1299
E S +P S A ++S+ P S + + AS +
Sbjct: 1610 EAVSGRVQLPQPLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHV 1669
Query: 1300 VPT--PEVAAI--PAASVPTPE--VPAIPAAAVPPMEEVSPIGVPFLGVSAHTDSVPISE 1353
VP+ +V A PA PT A ++A PP ++ +G G ++H ++
Sbjct: 1670 VPSVPQDVPAFVRPARVEPTDRDGGEAGESSAEPPPSDMGTVG----GQASHPQTLGARA 1725
Query: 1354 EGTP 1357
G+P
Sbjct: 1726 LGSP 1729
Score = 47.0 bits (110), Expect = 1e-04
Identities = 81/323 (25%), Positives = 111/323 (34%), Gaps = 65/323 (20%)
Query: 822 PVLEEWIPVLQRPSRTAAVPTVKDALD---AALPSPEEG-----------TSIAAVP--- 864
P + + P + PS A +P AL LP P + A +P
Sbjct: 829 PPPQYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLA 888
Query: 865 -APEGTAVVA---ALVPFPHEDILVASIVSLEEEDV-------------TAAAVSAPERA 907
AP G A ++ A+ P + + A+ + DV T + P +
Sbjct: 889 VAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQP 948
Query: 908 TVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEE 967
T+P V P+ T V P+ T P Q + P+ A +P+ E
Sbjct: 949 TLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPA-----LPVRPE 1003
Query: 968 DGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPT 1027
P+ P H PE+ AA P S AA VPT P
Sbjct: 1004 ------PLQP----HLPEQAAPAAT-------PGSQILLGHPAPYAVDVAAQVPTV--PV 1044
Query: 1028 SPAAAVPPP-EEPTSPAAAVPTPEEPTSPAAAVPTPEE-PTSPAAAVP--TPEEPTSPAA 1083
PAA + PP E PAA P+ P+S A + + PT A +P P P P
Sbjct: 1045 PPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLPPANPPLPGGPGI 1104
Query: 1084 AVPTPEEPTSPAAAVPTPEEPTS 1106
A P PT P EE S
Sbjct: 1105 ASPC---PTVQLTVEPVQEEQAS 1124
Score = 40.4 bits (93), Expect = 0.012
Identities = 44/166 (26%), Positives = 55/166 (33%), Gaps = 8/166 (4%)
Query: 999 EPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAA 1058
EP + AA P P+ + EEP AA P +P P T A
Sbjct: 28 EPRAKAAR-PGPQRFLRRSVVESDQEEPPGLEAAEAPGPQPPQPLQRRVLLLCKTRRLIA 86
Query: 1059 VPTPEEPTSPAAA--VPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE 1116
P +PA A V P P +PA A P P P P+ + P P+
Sbjct: 87 ERARGRPAAPAPAALVAQPGAPGAPADAGPEPVGTQEPG-----PDPIAAAVETAPAPDG 141
Query: 1117 PASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVA 1162
AA +E A A P P P +E AVA
Sbjct: 142 GPREEAAATVRKEDEGAAEAKPEPGRTRRDEPEEEEDDEDDLKAVA 187
Score = 38.9 bits (89), Expect = 0.036
Identities = 39/148 (26%), Positives = 50/148 (33%), Gaps = 10/148 (6%)
Query: 1038 EPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAV---PTPEEPTSPAAAVPTPEEPTSP 1094
EP + AA P P+ + EEP AA P P +P +
Sbjct: 28 EPRAKAAR-PGPQRFLRRSVVESDQEEPPGLEAAEAPGPQPPQPLQRRVLLLCKTRRLIA 86
Query: 1095 AAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPE 1154
A P P +PAA V P P +PA A P P P P+ A P P+
Sbjct: 87 ERARGRPAAP-APAALVAQPGAPGAPADAGPEPVGTQEPG-----PDPIAAAVETAPAPD 140
Query: 1155 ESASAAVAVPTPEESASPAAAVPTPAES 1182
A +E A A P P +
Sbjct: 141 GGPREEAAATVRKEDEGAAEAKPEPGRT 168
Score = 38.5 bits (88), Expect = 0.047
Identities = 40/145 (27%), Positives = 51/145 (35%), Gaps = 10/145 (6%)
Query: 1025 EPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAV---PTPEEPTSPAAAVPTPEEPTSP 1081
EP + AA P P+ + EEP AA P P +P +
Sbjct: 28 EPRAKAAR-PGPQRFLRRSVVESDQEEPPGLEAAEAPGPQPPQPLQRRVLLLCKTRRLIA 86
Query: 1082 AAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPE 1141
A P P +PAA V P P +PA A P P P P+ A+ P P+
Sbjct: 87 ERARGRPAAP-APAALVAQPGAPGAPADAGPEPVGTQEPG-----PDPIAAAVETAPAPD 140
Query: 1142 EPAFPAPAVPTPEESASAAVAVPTP 1166
A +E AA A P P
Sbjct: 141 GGPREEAAATVRKEDEGAAEAKPEP 165
Score = 37.4 bits (85), Expect = 0.10
Identities = 39/145 (26%), Positives = 48/145 (33%), Gaps = 10/145 (6%)
Query: 1064 EPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAV---PTPEEPTSPAAAVPTPEEPASP 1120
EP + AA P P+ + EEP AA P P +P +
Sbjct: 28 EPRAKAAR-PGPQRFLRRSVVESDQEEPPGLEAAEAPGPQPPQPLQRRVLLLCKTRRLIA 86
Query: 1121 AAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPA 1180
A P PA PAA V P P PA A P P P P+ A+ P P
Sbjct: 87 ERARGRPAAPA-PAALVAQPGAPGAPADAGPEP-----VGTQEPGPDPIAAAVETAPAPD 140
Query: 1181 ESASFAAVVATLEEPTSPAASVPTP 1205
A +E A + P P
Sbjct: 141 GGPREEAAATVRKEDEGAAEAKPEP 165
Score = 33.1 bits (74), Expect = 2.0
Identities = 41/157 (26%), Positives = 57/157 (36%), Gaps = 27/157 (17%)
Query: 1166 PEESASPA--------AAVPTPAESASFAAVVATLEEPTS-PAASVPTPAA--------- 1207
P A PA AA P P + V + EEP AA P P
Sbjct: 17 PGRGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAAEAPGPQPPQPLQRRVL 76
Query: 1208 -MVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEE 1266
+ T A P + PA+L V+ P P +PA A P EP + P+
Sbjct: 77 LLCKTRRLIAERARGRPAAPAPAAL---VAQPGAPGAPADAGP---EPVGTQEP--GPDP 128
Query: 1267 LSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTP 1303
+++ + P P+ AA + +E A A P P
Sbjct: 129 IAAAVETAPAPDGGPREEAAATVRKEDEGAAEAKPEP 165
Score = 31.2 bits (69), Expect = 7.5
Identities = 41/150 (27%), Positives = 51/150 (34%), Gaps = 15/150 (10%)
Query: 1188 VVATLEEPTSPA--ASVPTPAAMVATL--EEFTSPAASVPTSEEPASLAAAVSNPEEPTS 1243
V TL EP A A + P A A + F + EEP L AA + +P
Sbjct: 10 VPGTLMEPGRGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAAEAPGPQPPQ 69
Query: 1244 PAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTP 1303
P L T A ++PA PAA V+ P +PA A P P
Sbjct: 70 PLQRRVLLLCKTRRLIAERARGRPAAPA-----------PAALVAQPGAPGAPADAGPEP 118
Query: 1304 EVAAIPAASVPTPEVPAIPAAAVPPMEEVS 1333
P V PA P EE +
Sbjct: 119 VGTQEPGPDPIAAAVETAPAPDGGPREEAA 148
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 104 bits (259), Expect = 7e-22
Identities = 107/431 (24%), Positives = 154/431 (35%), Gaps = 91/431 (21%)
Query: 977 PATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPA------ 1030
P T++ P P V T +P+ P P P P P P P P+ A
Sbjct: 601 PYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSA 660
Query: 1031 ---------------------AAVPPPEEPTSPAAAV---------------PTPEEPTS 1054
A PP P + +V P P P +
Sbjct: 661 APMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPT 720
Query: 1055 PAAAV----PTPEEPTSPAAAVPTP-----EEPTSPAAAVPTPEEPTSPAAAVPTPEEPT 1105
P +A+ P P P+ P + P P + A PTP P A +P P+ P
Sbjct: 721 PGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLP-PQAPP 779
Query: 1106 SPAAAVPTPEE-----PASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAA 1160
P +P P P AA PTP P PA ++PAFPA +P +
Sbjct: 780 KPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPA-----KKQPAFPASYIPPSPPTPPVP 834
Query: 1161 VAVPT-PEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPA 1219
V PT P++ + A P+P + V + +++ S PTP AM + P
Sbjct: 835 VPPPTLPKQQSFCAKPPPSP-----LSPVPSVVKQIASQFPPPPTPPAME------SQPL 883
Query: 1220 ASVPTSEEPASLAAAVSNPE-EPTSPAAAVPTLEEPTSSAAAVLTPEELS--------SP 1270
VP + P S A + P+ +P+S P P ++ V P S P
Sbjct: 884 KPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPP 943
Query: 1271 AASVPTPEEPASPAAAVSNLEEPASPAAAVPTPE----VAAIPAASVPTPEVPAIPAAA- 1325
+ PTP++ SP S P PTP+ + + A P P+ P++ +
Sbjct: 944 PTASPTPDKSGSPGKKTSKTSSPGGKKPP-PTPQRNSSIKSSSGAEHPEPKRPSVDSLVS 1002
Query: 1326 --VPPMEEVSP 1334
PP E SP
Sbjct: 1003 KFTPPAESGSP 1013
Score = 96.3 bits (238), Expect = 2e-19
Identities = 103/383 (26%), Positives = 140/383 (36%), Gaps = 67/383 (17%)
Query: 993 RVSTPEEPASPAAAVP-TPEEPTSPAAAVPTPEE-----PTSPAAAVPPPEEPTSPAAAV 1046
+V+ P P P P P+ P P +P P P AA P P P PA
Sbjct: 757 QVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQ 816
Query: 1047 PT------PEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAV--------PTPEEP- 1091
P P P +P VP P P + P P SP +V P P P
Sbjct: 817 PAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPP 876
Query: 1092 ---TSPAAAVPTPEEPTSPAAAVPTPE-EPASPAAAVPTPE-EPASPAAAVPTPEEPAFP 1146
+ P VP P SP A P+ +P+S VP+P+ P P +++ P P P
Sbjct: 877 AMESQPLKPVPANVAPQSPPAVKAKPKWQPSS--IPVPSPDFPPPPPESSLVFPPPPPSP 934
Query: 1147 APAVPTPEESASAAVAVPTPEESASPAAAV------------PTPAESASF-AAVVATLE 1193
PA P P A PTP++S SP PTP ++S ++ A
Sbjct: 935 VPAPPPP----PPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHP 990
Query: 1194 EPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEE 1253
EP P+ + + +FT PA S S+E AA P + +P + +
Sbjct: 991 EPKRPSVD--------SLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQ 1042
Query: 1254 P--TSSAAAVLTPE------ELSSPAASVPTPEEPASPAAAVSNLEEPA------SPAAA 1299
S+ A VL+ E SP + P P + +E PA SP A
Sbjct: 1043 QGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVA 1102
Query: 1300 VPTPEVAAIPAASVPTPEVPAIP 1322
V P+ SV P P
Sbjct: 1103 VVNPQPQQWSKMSVKKAPPPTRP 1125
Score = 95.1 bits (235), Expect = 4e-19
Identities = 102/407 (25%), Positives = 146/407 (35%), Gaps = 61/407 (14%)
Query: 971 PEGPVTPATTVHAPEEPDTAAVRVS-TPEEPASPAAAVPTP-----EEPTSPAAAVPTPE 1024
P G V P P P +A ++ P P+ P + P P + A PTP
Sbjct: 705 PNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPP 764
Query: 1025 EPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAA 1084
P P A PP+ P P +P P + A V PT P ++P PA+
Sbjct: 765 PPP-PIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASY 823
Query: 1085 VPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAV-----------PTP----EE 1129
+P P PT P VP P P + P P SP +V PTP +
Sbjct: 824 IP-PSPPT-PPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQ 881
Query: 1130 PASPAAAVPTPEEP------------AFPAPAVPTPEESASAAVAVPTPEESASPA---- 1173
P P A P+ P + P P+ P +++ P P S PA
Sbjct: 882 PLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPP 941
Query: 1174 ---AAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPA- 1229
A PTP +S S + + +SP P P + + +S A P + P+
Sbjct: 942 PPPTASPTPDKSGSPGKKTS---KTSSPGGKKPPPTPQRNSSIK-SSSGAEHPEPKRPSV 997
Query: 1230 -SLAAAVSNPEEPTSPAAAVPTLEEPTS-------SAAAVLTPEELSSPAASVPTPEEPA 1281
SL + + P E SP+ TL P + + + V P L S P
Sbjct: 998 DSLVSKFTPPAESGSPSK--ETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSG 1055
Query: 1282 SPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPP 1328
+V P S + P P +P +P E+PA+ + P
Sbjct: 1056 RGKDSVVEFPSPPSDSDFPPPPPETELP---LPPIEIPAVFSGNTSP 1099
Score = 89.0 bits (219), Expect = 3e-17
Identities = 101/384 (26%), Positives = 146/384 (38%), Gaps = 63/384 (16%)
Query: 970 TPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSP 1029
T P TP V + ++PA PA+ +P P PT P VP P P
Sbjct: 799 TQAAPPTPTPPVPPAK------------KQPAFPASYIP-PSPPT-PPVPVPPPTLPKQQ 844
Query: 1030 AAAVPPPEEPTSPAAAV--------PTPEEP----TSPAAAVPTPEEPTSPAAAVPTPE- 1076
+ PP P SP +V P P P + P VP P SP A P+
Sbjct: 845 SFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKW 904
Query: 1077 EPTSPAAAVPTPE-EPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAA 1135
+P+S VP+P+ P P +++ P P SP VP P P P A+ PTP++ SP
Sbjct: 905 QPSS--IPVPSPDFPPPPPESSLVFPPPPPSP---VPAPPPPPPPTAS-PTPDKSGSPGK 958
Query: 1136 AVPTPEEPAFPAPAVPTPEES----ASAAVAVPTPEESA--SPAAAVPTPAESASFAAVV 1189
P P PTP+ + +S+ P P+ + S + PAES S +
Sbjct: 959 KTSKTSSPGGKKPP-PTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSK-- 1015
Query: 1190 ATLEEPTSP-------AASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPT 1242
TL P +P + V P + +P S + + S+ + P
Sbjct: 1016 ETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPP 1075
Query: 1243 SPAAA---VPTLEEP------TSSAAAVLTPEELSSPAASVPTPEEPASP----AAAVSN 1289
P +P +E P TS AV+ P+ SV P P + ++
Sbjct: 1076 PPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQ 1135
Query: 1290 LEEPASPAAAVPTPEVAAIPAASV 1313
E P A P+V P +S+
Sbjct: 1136 AEISEQPTMATVVPQVPTSPKSSL 1159
Score = 76.6 bits (187), Expect = 2e-13
Identities = 87/340 (25%), Positives = 123/340 (36%), Gaps = 49/340 (14%)
Query: 1039 PTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTS---PA 1095
P SP + TP + P+ +P P P P P P P P+ + P+
Sbjct: 608 PLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKY 667
Query: 1096 AAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEE 1155
+ + + + + A+ P P + P+ P VP P P P PTP
Sbjct: 668 STITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPP----PPPPPPTPGS 723
Query: 1156 SAS----AAVAVPTPEESASP------------AAAVPTPAESASFAAVVATLEEPTSPA 1199
+ + A A P+ SA P A PTP A + + P P
Sbjct: 724 AMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPP-QAPPKPL 782
Query: 1200 ASVPTP-----AAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEP 1254
++P P A V T +P VP +++ + A+ P PT P P
Sbjct: 783 VTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPK 842
Query: 1255 TSSAAAVLTPEELSSPAASV---------PTPEEPA---SPAAAVSNLEEPASPAA--AV 1300
S A P L SP SV P P PA P V P SP A A
Sbjct: 843 QQSFCAKPPPSPL-SPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAK 901
Query: 1301 PTPEVAAIPAASVPTPEVPAIP--AAAVPPMEEVSPIGVP 1338
P + ++IP VP+P+ P P ++ V P SP+ P
Sbjct: 902 PKWQPSSIP---VPSPDFPPPPPESSLVFPPPPPSPVPAP 938
Score = 70.9 bits (172), Expect = 8e-12
Identities = 109/471 (23%), Positives = 156/471 (33%), Gaps = 57/471 (12%)
Query: 828 IPVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVAS 887
+P P + V+ A P+P I A P+ +P P VA
Sbjct: 737 LPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAP 796
Query: 888 IVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAIT-QEGMS 946
+V T AA P PA P A+ S P P + Q+
Sbjct: 797 VV-------TQAAPPTPTPPVPPAK--KQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFC 847
Query: 947 AVAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAA 1006
A SP ++ I + P TP P +P A V +P PA A
Sbjct: 848 AKPPPSPLSPVPSVVKQIASQFPPPP---TPPAMESQPLKPVPANVAPQSP--PAVKAKP 902
Query: 1007 VPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPT 1066
P P+ P P +S PPP +P P P PT A PTP++
Sbjct: 903 KWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAP----PPPPPPT----ASPTPDKSG 954
Query: 1067 SPAAAVPTPEEPTSPAAAVPTPEE----PTSPAAAVPTPEEPT--SPAAAVPTPEEPASP 1120
SP P PTP+ +S A P P+ P+ S + P E SP
Sbjct: 955 SPGKKTSKTSSPGGKKPP-PTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSP 1013
Query: 1121 AAAVPTPEEPASPAAAVPTPEEPAFPAPAVP-TPEESASAAVAVPTPEESASPAAAVPTP 1179
+ +E P AA P P + +P ++ +A A P+P
Sbjct: 1014 S------KETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSP 1067
Query: 1180 AESASFAAVVATLEEPTSPAASVPTPAAMV-ATLEEFTSPAASVPTSEEPASLAAAVSNP 1238
+ F P P +P P + A TSP +V + +V
Sbjct: 1068 PSDSDF--------PPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKA 1119
Query: 1239 EEPTSPAAAVPTLEEPTSSAAAVLTPEELS-SPAASVPTPEEPASPAAAVS 1288
PT P + + LT E+S P + P+ P SP +++S
Sbjct: 1120 PPPT----------RPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLS 1160
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 104 bits (259), Expect = 7e-22
Identities = 140/513 (27%), Positives = 202/513 (39%), Gaps = 60/513 (11%)
Query: 829 PVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAV---VAALVPFPHEDILV 885
P + + AA T+ L +PS G + + +P P + + V++ V P L
Sbjct: 1383 PEVSASAPGAAPLTISSPLH--VPSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLP 1440
Query: 886 ASIVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGM 945
S+ + A SAP + A G A + +V+ P AP V AA +
Sbjct: 1441 ISVPT-----TLPAPASAPLTIPISAPLTVSASGPALLTSVTPP--LAPVVPAAPGPPSL 1493
Query: 946 SAVAGFSPEWAALAI---TVPITEEDGTPEGPVTPA-TTVHAPEEPDTAAVRVSTPEEPA 1001
A +G SP +AL + T P TP P+ A T+ H P T A S PA
Sbjct: 1494 -APSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPA 1552
Query: 1002 SPAAA-VPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVP 1060
S A+ P+ P A++ P S A A P +P AA T A P
Sbjct: 1553 SALASPFPSAPNPAPAQASLLAPASSASQALATP-----LAPMAAPQT-------AILAP 1600
Query: 1061 TPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASP 1120
+P P +P P SP AA T P+ TS A+A P P
Sbjct: 1601 SPAPPLAPL-----PVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVP------ 1649
Query: 1121 AAAVPTPE-EPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTP 1179
PTP P+S +P P P+PA T + + A+A S S ++ T
Sbjct: 1650 ---APTPVLAPSSTQTMLPAPVPSPLPSPA-STQTLALAPALAPTLGGSSPSQTLSLGTG 1705
Query: 1180 AESASFAAVVATLEEPTSPAAS-VPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNP 1238
F +L +PA+S VPTPA ++ +P + ++ + A P
Sbjct: 1706 NPQGPFPTQTLSL----TPASSLVPTPAQTLSL-----APGPPLGPTQTLSLAPAPPLAP 1756
Query: 1239 EEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPA---S 1295
P PA A P SS+A++L P + + S P P PAAA + PA S
Sbjct: 1757 ASPVGPAPAHTLTLAPASSSASLLAPASVQTLTLS-PAPVPTLGPAAAQTLALAPASTQS 1815
Query: 1296 PAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPP 1328
PA+ + V+A AA +P V +P + P
Sbjct: 1816 PASQASSLVVSASGAAPLPVTMVSRLPVSKDEP 1848
Score = 100 bits (250), Expect = 8e-21
Identities = 143/562 (25%), Positives = 221/562 (39%), Gaps = 72/562 (12%)
Query: 838 AAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEEEDVT 897
A PT + LPS T+ PAP G ++ A P + +V +
Sbjct: 1262 AVAPTPGPTPVSVLPSSTPSTT----PAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQAP 1317
Query: 898 A---------AAVSAPERATVPAV-----TVS---VPEGTAAVAAVSSPEETAPAVAAAI 940
A P + +PAV T++ +P T A P T +
Sbjct: 1318 RDGLTPVPPLAPAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKL 1377
Query: 941 TQEGMSAVAGFSPEWAALAITVPITEEDGTPEG-----PVTPATTVHAPEE-----PDTA 990
V+ +P A L I+ P+ P P+ ++ + +P P ++
Sbjct: 1378 VHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSS 1437
Query: 991 AVRVSTPEEPASPAAA-------VPTPEEPTSPA--AAVPTPEEPTSPAAAVPPPEEPT- 1040
++ +S P +PA+A P + PA +V P P PAA PP P+
Sbjct: 1438 SLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSG 1497
Query: 1041 -SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEP---TSPAAAVPTPEEPTSPAA 1096
SP+A+ T T+P ++ + + P P PT S A +P + A
Sbjct: 1498 ASPSASALTLGLATAP--SLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPASAL 1555
Query: 1097 AVPTPEEPTSPAAAVPTPEEPASPAA-AVPTPEEP-ASPAAAV--PTPEEPAFPAPAV-P 1151
A P P P +PA A + PAS A+ A+ TP P A+P A+ P+P P P P + P
Sbjct: 1556 ASPFPSAP-NPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAP 1614
Query: 1152 TPEES---ASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAM 1208
+P + AS+ VP S++P ++ + + + V+A T A VP+P
Sbjct: 1615 SPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPS 1674
Query: 1209 VATLEEFTSPAASVPT---SEEPASLAAAVSNPEEP--------TSPAAAVPTLEEPTSS 1257
A+ + A PT S +L+ NP+ P T ++ VPT + S
Sbjct: 1675 PASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSL 1734
Query: 1258 A-AAVLTPEELSSPAASVP-TPEEPASPAAAVSNLEEPASPAAAVPTP---EVAAIPAAS 1312
A L P + S A + P P P PA A + PAS +A++ P + + A
Sbjct: 1735 APGPPLGPTQTLSLAPAPPLAPASPVGPAPAHTLTLAPASSSASLLAPASVQTLTLSPAP 1794
Query: 1313 VPTPEVPAIPAAAVPPMEEVSP 1334
VPT A A+ P SP
Sbjct: 1795 VPTLGPAAAQTLALAPASTQSP 1816
Score = 92.4 bits (228), Expect = 3e-18
Identities = 154/638 (24%), Positives = 228/638 (35%), Gaps = 112/638 (17%)
Query: 817 AGNTEPVLEEWIPVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALV 876
+G+ VL + VL SR PT+ + P+P ++ P P ++++ L
Sbjct: 1079 SGSLPQVLPSPLGVLSGTSRPPT-PTL-----SLKPTPPAPVRLSPAPPPGSSSLLKPLT 1132
Query: 877 PFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAV 936
P A+ + TA + P P + P+ A + S E +
Sbjct: 1133 VPPGYTFPPAAATTTSTTTATATTTAVPAPTPAPQRLILSPD---MQARLPSGEVVSIGQ 1189
Query: 937 AAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVR--- 993
A++ Q ++ G P +T I T G V P V
Sbjct: 1190 LASLAQRPVANAGGSKP------LTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVS 1243
Query: 994 -------VSTPEEPASPAAAVPTPEE------PTSPAAAVPTPEEPTSPAAA--VPPPEE 1038
+S P A A PTP P+S + P P + P AA VPP
Sbjct: 1244 AGGQHHLISQPAHVALIQAVAPTPGPTPVSVLPSSTPSTTPAPTGLSLPLAANQVPPTMV 1303
Query: 1039 PTSPAAAVPTPEEPTSPAAAVP----TPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSP 1094
+ + + P VP P P+S AV P PT +PTP T+
Sbjct: 1304 NNTGVVKIVVRQAPRDGLTPVPPLAPAPRPPSSGLPAVLNPR-PTLTPGRLPTPTLGTA- 1361
Query: 1095 AAAVPTPE--EPTSPAAAVPTPEEPAS-PAAAVPTPEEPASPAAAVPTPEEPAFPAPAVP 1151
A +PTP P P+PE AS P AA T P +++P P P P
Sbjct: 1362 RAPMPTPTLVRPLLKLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSS 1421
Query: 1152 TPEESASAAVAVP--------TPEESASPAAA---VPTPAE---SASFAAVVATLEEPTS 1197
S+ V+VP P +PA+A +P A SAS A++ ++ P +
Sbjct: 1422 PLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLA 1481
Query: 1198 P-----------AASVPTPAAMVATLEEFTSPAAS-----------VPTSEEPASL---- 1231
P A S +P+A TL T+P+ S PTS L
Sbjct: 1482 PVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTV 1541
Query: 1232 ----------AAAVSNP-EEPTSPAAAVPTLEEPTSSA----AAVLTPEELSSPAASVPT 1276
A+A+++P +PA A +L P SSA A L P A P+
Sbjct: 1542 APACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPS 1601
Query: 1277 PEEPASP----------AAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAV 1326
P P +P A +++ + P A TP + A+ VP P P A
Sbjct: 1602 PAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAP----TPVLAP 1657
Query: 1327 PPMEEVSPIGVPF-LGVSAHTDSVPISEEGTPVLEEAS 1363
+ + P VP L A T ++ ++ P L +S
Sbjct: 1658 SSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSS 1695
Score = 65.9 bits (159), Expect = 3e-10
Identities = 99/388 (25%), Positives = 133/388 (34%), Gaps = 58/388 (14%)
Query: 969 GTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTS 1028
GT G + APE P T RVS A T A P +
Sbjct: 2373 GTGGGTHRRSKKAKAPERPGT---RVSERLRGA---------RAETQGANHTPVISAHQT 2420
Query: 1029 PAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTP 1088
+ PP P P P +PA+A P + A VP P + P P
Sbjct: 2421 RSTTTPPRCSPARERVPRPAPRPRPTPASA------PAAIPALVPVP-------VSAPVP 2467
Query: 1089 EEPTSPAAAVPTPEEPT-SPAAAVPTPEEPA--SPAAAVPTPEEPASPA-AAVPTPEEP- 1143
+P +P P+ P + +P PA P A P P PA + TP P
Sbjct: 2468 ISAPNPITILPVHILPSPPPPSQIPPCSSPACTPPPACTPPPAHTPPPAQTCLVTPSSPL 2527
Query: 1144 AFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVP 1203
P+VP + + + E + A A P E AS A+ + P +P
Sbjct: 2528 LLGPPSVPISASVTNLPLGLRPEAELCAQALASPESLELASVASSETSSLSLVPPKDLLP 2587
Query: 1204 ---------------TPAAMVATLEEFTSP---AASVPTSEEPASLAAAVSNPEEPTSPA 1245
TP+A TLE + P P S E +L E P +
Sbjct: 2588 VAVEILPVSEKNLSLTPSAPSLTLEAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVS 2647
Query: 1246 AAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEV 1305
+ LE P S+A + E L P + T EE S+ E+P + T EV
Sbjct: 2648 ES-NGLELPPSAA----SDEPLQEPLEADRTSEELTEAKTPTSSPEKPQE----LVTAEV 2698
Query: 1306 AAIPAASVPTPEVPAIPAAAVPPMEEVS 1333
AA P+ S P P+ A PP S
Sbjct: 2699 AA-PSTSSSATSSPEGPSPARPPRRRTS 2725
Score = 63.5 bits (153), Expect = 1e-09
Identities = 87/338 (25%), Positives = 123/338 (36%), Gaps = 54/338 (15%)
Query: 1008 PTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTS 1067
P P++ V P P P PPP P A P P PA+ + + S
Sbjct: 1000 PVPKQEGRTVVVVNNPRAPLGPVPVRPPPG-PELSAQPTPGPVPQVLPASLMVS----AS 1054
Query: 1068 PAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTP 1127
PA P PA+ P P + P +P S + P+ SP +
Sbjct: 1055 PAGP------PLIPASRPPGP--------VLLPPLQPNSGS----LPQVLPSPLGVLSGT 1096
Query: 1128 EEPASPAAAV-PTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFA 1186
P +P ++ PTP P +PA P S + VP P + PAAA T +A+
Sbjct: 1097 SRPPTPTLSLKPTPPAPVRLSPAPPPGSSSLLKPLTVP-PGYTFPPAAATTTSTTTAT-- 1153
Query: 1187 AVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAA 1246
T+ A PTPA L A +P S E S+ S + P + A
Sbjct: 1154 --------ATTTAVPAPTPAPQRLILS--PDMQARLP-SGEVVSIGQLASLAQRPVANAG 1202
Query: 1247 AVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEP-----ASPAAAVSNLEEPASPA---A 1298
L LT ++ A P P + S + +PA A A
Sbjct: 1203 GSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLISQPAHVALIQA 1262
Query: 1299 AVPTP---EVAAIPA---ASVPTPEVPAIPAAA--VPP 1328
PTP V+ +P+ ++ P P ++P AA VPP
Sbjct: 1263 VAPTPGPTPVSVLPSSTPSTTPAPTGLSLPLAANQVPP 1300
Score = 63.2 bits (152), Expect = 2e-09
Identities = 101/440 (22%), Positives = 150/440 (34%), Gaps = 69/440 (15%)
Query: 984 PEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEE-----PTSPAAAVPPPEE 1038
P++ V V+ P P P VP P +A PTP P S + P
Sbjct: 1002 PKQEGRTVVVVNNPRAPLGP---VPVRPPPGPELSAQPTPGPVPQVLPASLMVSASPAGP 1058
Query: 1039 PTSPAAAVPTPE-----EPTSPAA--AVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEP 1091
P PA+ P P +P S + +P+P S + PTP P P P
Sbjct: 1059 PLIPASRPPGPVLLPPLQPNSGSLPQVLPSPLGVLSGTSRPPTPTLSLKPTPPAPVRLSP 1118
Query: 1092 TSPAAA------VPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPA- 1144
P + + P T P AA T + A P +P + +P+ A
Sbjct: 1119 APPPGSSSLLKPLTVPPGYTFPPAAATTTSTTTATATTTAVPAPTPAPQRLILSPDMQAR 1178
Query: 1145 FPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPT 1204
P+ V + + AS A P +A + + + A + + A P
Sbjct: 1179 LPSGEVVSIGQLASLA---QRPVANAGGSKPLTFQIQGNKLTLTGAQVRQ---LAVGQPR 1232
Query: 1205 P--------------------AAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSP 1244
P A VA ++ P S P+S + P + P
Sbjct: 1233 PLQRNVVHLVSAGGQHHLISQPAHVALIQAVAPTPGPTPVSVLPSSTPSTTPAPTGLSLP 1292
Query: 1245 AAA---VPTLEEPTSSAAAVL--TPEELSSPAASV-PTPEEPASPAAAVSNLEEPASPA- 1297
AA PT+ T V+ P + +P + P P P+S AV N +P
Sbjct: 1293 LAANQVPPTMVNNTGVVKIVVRQAPRDGLTPVPPLAPAPRPPSSGLPAVLNPRPTLTPGR 1352
Query: 1298 ----------AAVPTPEVA--AIPAASVPTPEVPAIPAAAVPPMEEVSPIGVPFLGVSAH 1345
A +PTP + + P+PEV A A P+ SP+ VP
Sbjct: 1353 LPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSA-SAPGAAPLTISSPLHVPSSLPGPA 1411
Query: 1346 TDSVPISEEGTPVLEEASST 1365
+ +PI +P+ SST
Sbjct: 1412 SSPMPI-PNSSPLASPVSST 1430
Score = 58.5 bits (140), Expect = 4e-08
Identities = 115/558 (20%), Positives = 197/558 (35%), Gaps = 76/558 (13%)
Query: 828 IPVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPF---PHEDIL 884
+ +L P + +P A P P A P P T +V P P +
Sbjct: 2479 VHILPSPPPPSQIPPCSSP--ACTPPPACTPPPAHTPPPAQTCLVTPSSPLLLGPPSVPI 2536
Query: 885 VASIVSLE-----EEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAA 939
AS+ +L E ++ A A+++PE + +V S T++++ V + AV
Sbjct: 2537 SASVTNLPLGLRPEAELCAQALASPESLELASVASSE---TSSLSLVPPKDLLPVAVEIL 2593
Query: 940 ITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPV-TPATTVHAPEEPDTAAVRVSTPE 998
E ++ +P A ++P +E P+ T T + EE + E
Sbjct: 2594 PVSEKNLSLTPSAPSLTLEAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLE 2653
Query: 999 EPASPAAAVPTPEEPTSPAAAVPTPEEPT---SPAAAVPPPEEPTSPAAAVPTPEEPTSP 1055
P S A+ P E P A T EE T +P ++ P+E + A P+ +
Sbjct: 2654 LPPSAASDEPLQE----PLEADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATS 2709
Query: 1056 AAAVPTPEEPTSPAAAVPT---------PEEPTSPAAAVPTP-----------------E 1089
+ P+P P + P +P P P +
Sbjct: 2710 SPEGPSPARPPRRRTSADVEIRGQGTGRPGQPPGPKVLRKLPGRLVTVVEEKELVRRRRQ 2769
Query: 1090 EPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPT--PEEPASPAAAVPTPEEPAFPA 1147
+ + + VP E TS + P+ + P ++ P P E A+P++++PTP + F A
Sbjct: 2770 QRGAASTLVPGVSE-TSASPGSPSVRSMSGPESSPPIGGPCE-AAPSSSLPTPPQQPFIA 2827
Query: 1148 --------PAVPTPEESASAAVAVPTP---EESASPAAAVPTPAESASFA--AVVATLEE 1194
+PE A +A+ P P +PA++ A +TL+
Sbjct: 2828 RRHIELGVTGGGSPENGDGALLAITPPAVKRRRGRPPKKNRSPADAGRGVDEAPSSTLKG 2887
Query: 1195 PTSPAASVPTPAAMVA---TLEEFTSPAASVPTSEEPASLAAAVSNPEE-------PTSP 1244
T+ A VP P ++ LE P P +P + +P E P +
Sbjct: 2888 KTNGADPVPGPETLIVADPVLEPQLIPGPQ-PLGPQPVHRPNPLLSPVEKRRRGRPPKAR 2946
Query: 1245 AAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPE 1304
+P + + P+ P P P A V+N + + + P
Sbjct: 2947 DLPIPGTISSAGDGNSESRTQPPPHPSPLTPLPPLLVCPTATVANTVTTVTISTS-PPKR 3005
Query: 1305 VAAIPAASVPTPEVPAIP 1322
P + P+P +P
Sbjct: 3006 KRGRPPKNPPSPRPSQLP 3023
Score = 53.9 bits (128), Expect = 1e-06
Identities = 102/447 (22%), Positives = 146/447 (32%), Gaps = 50/447 (11%)
Query: 942 QEGMSAVAGFSPEWAALAITV-----PITEEDGTPEGPVTPATTVHAPEEPDTAAVRVST 996
QEG + V +P + V P TP GPV A +
Sbjct: 1004 QEGRTVVVVNNPRAPLGPVPVRPPPGPELSAQPTP-GPVPQVLPASLMVSASPAGPPLIP 1062
Query: 997 PEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPE---EPTSPAAAVPTPEEP- 1052
P P P S +P+P S + P P +PT PA +P P
Sbjct: 1063 ASRPPGPVLLPPLQPNSGSLPQVLPSPLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAPPP 1122
Query: 1053 --TSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPE-EPTSPAA 1109
+S + P T P AA T T+ A P +P + +P+ + P+
Sbjct: 1123 GSSSLLKPLTVPPGYTFPPAAATTTSTTTATATTTAVPAPTPAPQRLILSPDMQARLPSG 1182
Query: 1110 AVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEE- 1168
V + + AS A + P + A T + AV P P +
Sbjct: 1183 EVVSIGQLASLA------QRPVANAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQR 1236
Query: 1169 -------SASPAAAVPTPAESASFAAVVATLEE------PTSPAASVPTPAAMVATLEEF 1215
+ + PA A AV T P+S ++ P P + L
Sbjct: 1237 NVVHLVSAGGQHHLISQPAHVALIQAVAPTPGPTPVSVLPSSTPSTTPAPTGLSLPLAAN 1296
Query: 1216 TSPAASV-PTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASV 1274
P V T + A + P P A P P+S AVL P +P +
Sbjct: 1297 QVPPTMVNNTGVVKIVVRQAPRDGLTPVPPLAPAP--RPPSSGLPAVLNPRPTLTP-GRL 1353
Query: 1275 PTPE-EPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVP--------TPEVPAIPAAA 1325
PTP A L P P+PEV+A + P P PA++
Sbjct: 1354 PTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPASS 1413
Query: 1326 VPPMEEVSPIGVPFLGVSAHTDSVPIS 1352
P+ SP+ P + T SVP+S
Sbjct: 1414 PMPIPNSSPLASPV----SSTVSVPLS 1436
Score = 46.6 bits (109), Expect = 2e-04
Identities = 62/236 (26%), Positives = 94/236 (39%), Gaps = 31/236 (13%)
Query: 1131 ASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVA 1190
A A TP A + TP + A VP P A P P +++ AA+ A
Sbjct: 2404 AETQGANHTPVISAHQTRSTTTPPRCSPARERVPRP-------APRPRPTPASAPAAIPA 2456
Query: 1191 TLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPT 1250
+ P S A VP A T+ P +P+ P+ + S+P PA P
Sbjct: 2457 LVPVPVS--APVPISAPNPITI----LPVHILPSPPPPSQIPPC-SSPACTPPPACTPPP 2509
Query: 1251 LEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAA-----AVPTPEV 1305
P + ++TP SSP P P P S A+V+NL P A A+ +PE
Sbjct: 2510 AHTPPPAQTCLVTP---SSPLLLGP-PSVPIS--ASVTNLPLGLRPEAELCAQALASPE- 2562
Query: 1306 AAIPAASVPTPEVPAI----PAAAVPPMEEVSPIGVPFLGVSAHTDSVPISEEGTP 1357
++ ASV + E ++ P +P E+ P+ L ++ S+ + P
Sbjct: 2563 -SLELASVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPSAPSLTLEAGSIP 2617
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 103 bits (256), Expect = 2e-21
Identities = 109/467 (23%), Positives = 170/467 (36%), Gaps = 75/467 (16%)
Query: 960 ITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAA 1019
+T P+ ++ GT + PV P T P +P A + P++ P P+ P
Sbjct: 338 LTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGV 397
Query: 1020 VPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEP--TSPAAAVPTPEEPTSPAAAVPTPEE 1077
TP + PA PP ++ +P P ++P SPA A + P P +
Sbjct: 398 GKTPAQQPGPAK--PPTQQVGTPK---PLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQ 452
Query: 1078 PTSPAAAVPTPEEPTSPAAAVPTPEEPT--SPAAAVPTPEEPASPAAAVPTPEEPASPAA 1135
P PT P + +P P +P P A P P++P S A P ++P S
Sbjct: 453 QAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGS---AKPPSQQPGS--- 506
Query: 1136 AVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVAT---- 1191
T P P PA P+P++ S P SA P+A P+PA+ ++ +
Sbjct: 507 ---TKPPPQQPGPAKPSPQQPGSTKPPSQQPG-SAKPSAQQPSPAKPSAQQSTKPVSQTG 562
Query: 1192 ----LEEPT-SPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVS---------- 1236
L+ PT SP+A P + T+ + + E A+
Sbjct: 563 SGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCG 622
Query: 1237 -NPEEPTSPA------------------AAVPTLEEPTSSAAAVLTPEELS--SPAASVP 1275
NP + A VP+ +P A V T +S SP
Sbjct: 623 FNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQT 682
Query: 1276 TPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPMEEVSPI 1335
+P++ A+P +S EP P V P + P+A P + PP E
Sbjct: 683 SPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEP---- 738
Query: 1336 GVPFLGVSAHTDSVPISEEG-------TPVLEEASSTGMWIKEDLDS 1375
V + D P++++ P + SS+ K D+ S
Sbjct: 739 -----SVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPS 780
Score = 85.5 bits (210), Expect = 3e-16
Identities = 86/377 (22%), Positives = 134/377 (35%), Gaps = 40/377 (10%)
Query: 966 EEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAA------- 1018
++DGTP+ + + P T + P + A +P + + P
Sbjct: 231 QQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVR 290
Query: 1019 ------AVPTPEEPT--SPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEP---TS 1067
++P+P +P P PP ++P E + P A P P +P T
Sbjct: 291 GESVKPSLPSPSKPPIQQPTPGKPPAQQP---------GHEKSQPGPAKP-PAQPSGLTK 340
Query: 1068 PAAAVP-TPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPT 1126
P A P T + P P P +P PA P++ P P+ A P T
Sbjct: 341 PLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKT 400
Query: 1127 PEEPASPAAAVPTPEEPAFPAPAVPTP--EESASAAVAVPTPEESASPAAAVPTPAESAS 1184
P + P A P ++ P P P + A A TP + P PA+ A
Sbjct: 401 PAQ--QPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPG---KIPAQQAG 455
Query: 1185 FAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSP 1244
A PT P + +P PA P P S +P S + P P P
Sbjct: 456 PGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKP-PPQQP 514
Query: 1245 AAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPT-- 1302
A P+ ++P S+ P + P+A P+P +P++ + + + PT
Sbjct: 515 GPAKPSPQQPGSTKPPSQQPGS-AKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVS 573
Query: 1303 PEVAAIPAASVPTPEVP 1319
P P+ +P P
Sbjct: 574 PSAKQPPSQGLPKTICP 590
Score = 81.3 bits (199), Expect = 6e-15
Identities = 104/422 (24%), Positives = 164/422 (38%), Gaps = 37/422 (8%)
Query: 927 SSPE---ETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHA 983
SSP+ +TAP + + SP+ A P + PE P P V
Sbjct: 655 SSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDA----APKQDLSKAPE-PKKPPPLVKQ 709
Query: 984 PEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTP---EEPTSPAAAVPPPEEPT 1040
P + + + P E S + P P+EP+ P+ P ++P P V P +
Sbjct: 710 PTLHGSPSAKAKQPPEADSLSKPAP-PKEPSVPSEQDKAPVADDKPKQPKM-VKPTTDLV 767
Query: 1041 SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSP--AAAV 1098
S ++A P+ P+S + EE T+P P + P+ + P E SP + A+
Sbjct: 768 SSSSATTKPDIPSSKVQS--QAEEKTTP----PLKTDSAKPSQSFPPTGEKVSPFDSKAI 821
Query: 1099 PTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAA----VPTPEEPAFPAPAVPTPE 1154
P P S + P P + V ++ P A P P+ P + P
Sbjct: 822 PRPAS-DSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPG 880
Query: 1155 ESASAAVAVPTPEESASPAAAVPTPAESASFAAVV-ATLEEPTSPAASVPTPAAMVATLE 1213
+A VPTP++S P + S + ++ A +PT+P +V T
Sbjct: 881 PRPTAGQTVPTPQQSPKPQE--QSRRFSLNLGSITDAPKSQPTTPQETV-TGKLFGFGAS 937
Query: 1214 EFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAAS 1273
F+ + + T+ +P + + +PA + P PTS T + +PA S
Sbjct: 938 IFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQP----PTSQGPPKSTGQAPPAPAKS 993
Query: 1274 VPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPME-EV 1332
+P +E +PAA LE A A V E P + + A P AV P + E
Sbjct: 994 IPVKKETKAPAA--EKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEK 1051
Query: 1333 SP 1334
SP
Sbjct: 1052 SP 1053
Score = 74.7 bits (182), Expect = 6e-13
Identities = 101/439 (23%), Positives = 166/439 (37%), Gaps = 65/439 (14%)
Query: 904 PERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVP 963
P+ T P T S A + P++T+P AA Q+ A P P
Sbjct: 659 PKLKTAPVTTTS-----AVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPP--------P 705
Query: 964 ITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTP---EEPTSPAAAV 1020
+ ++ P +P+ P E D+ + + + P+EP+ P+ P ++P P
Sbjct: 706 LVKQ---PTLHGSPSAKAKQPPEADSLS-KPAPPKEPSVPSEQDKAPVADDKPKQPKMVK 761
Query: 1021 PTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTS 1080
PT + +S ++A P+ P+S + EE T+P P + P+ + P E S
Sbjct: 762 PTTDLVSS-SSATTKPDIPSSKVQS--QAEEKTTP----PLKTDSAKPSQSFPPTGEKVS 814
Query: 1081 P--AAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAV----PTPEEPASPA 1134
P + A+P P S + P P + V ++ P A P P+ P
Sbjct: 815 PFDSKAIPRPASD-SKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPK 873
Query: 1135 AAVPTPEEPAFPA-PAVPTPEESASAAVAVPTPEESA------------SPAAAVPTPAE 1181
+ PTP P A VPTP++S P P+E + +P + TP E
Sbjct: 874 GS-PTPPGPRPTAGQTVPTPQQS-------PKPQEQSRRFSLNLGSITDAPKSQPTTPQE 925
Query: 1182 SAS-----FAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPT-SEEPASLAAAV 1235
+ + F A + + A P P + +P P S+ P S
Sbjct: 926 TVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGP----GAPMKQAPAPSQPPTSQGPPK 981
Query: 1236 SNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPAS 1295
S + P +PA ++P +E + AA L P+ +P E+ P +L
Sbjct: 982 STGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQ 1041
Query: 1296 PAAAVPTPEVAAIPAASVP 1314
A E + P ++ P
Sbjct: 1042 KAVLPTKLEKSPKPESTCP 1060
Score = 69.3 bits (168), Expect = 2e-11
Identities = 88/387 (22%), Positives = 135/387 (34%), Gaps = 63/387 (16%)
Query: 1002 SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPT 1061
+P + P P+ T+P + +SP P++ +P + EP P V
Sbjct: 651 APVPSSPQPKLKTAPVTTTSAVSK-SSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQ 709
Query: 1062 PEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTP---EEPTSPAAAVPTPEEPA 1118
P SP+A P E S + P P+EP+ P+ P ++P P PT +
Sbjct: 710 PTLHGSPSAKAKQPPEADSLSKPAP-PKEPSVPSEQDKAPVADDKPKQPKMVKPT-TDLV 767
Query: 1119 SPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASP--AAAV 1176
S ++A P+ P+S + EE P P +SA + + P E SP + A+
Sbjct: 768 SSSSATTKPDIPSSKVQS--QAEEKTTP----PLKTDSAKPSQSFPPTGEKVSPFDSKAI 821
Query: 1177 PTPAESASFAA---------------VVATLEEPT------------------SPAASVP 1203
P PA + + V EEP SP P
Sbjct: 822 PRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGP 881
Query: 1204 TPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPE-EPTSP-----------AAAVPTL 1251
P A SP + +L + P+ +PT+P A++ +
Sbjct: 882 RPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQ 941
Query: 1252 EEPTSSAAAVLTPEELSSPAA---SVPTPEE-PASPAAAVSNLEEPASPAAAVPTPEVAA 1307
S A P S P A P P + P S S + P +PA ++P +
Sbjct: 942 ASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETK 1001
Query: 1308 IPAASVPTPEVPAIPAAAVPPMEEVSP 1334
PAA P+ P E+ P
Sbjct: 1002 APAAEKLEPKAEQAPTVKRTETEKKPP 1028
Score = 65.9 bits (159), Expect = 3e-10
Identities = 95/396 (23%), Positives = 153/396 (38%), Gaps = 53/396 (13%)
Query: 810 PEKQVTKAGNTE--PVLEEWIPVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPE 867
P++ ++KA + P L + + PS A P D+L P E +VP+ +
Sbjct: 690 PKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEP-----SVPSEQ 744
Query: 868 GTAVVAALVPFPHEDI-----LVASIVSLEEEDVTAAAVS--APERATVPAVTVSVPEGT 920
A VA P + + LV+S + + D+ ++ V A E+ T P T S
Sbjct: 745 DKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDS----- 799
Query: 921 AAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTPATT 980
+ P ++ P ++ A+ + + ++ P +E G + V P
Sbjct: 800 ------AKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQ--VDP--- 848
Query: 981 VHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAA-AVPTPEEPTSP---------- 1029
V EEP A ++S + PTP P A VPTP++ P
Sbjct: 849 VQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLN 908
Query: 1030 --AAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAV-- 1085
+ P +PT+P V + A++ + A P P + P A +
Sbjct: 909 LGSITDAPKSQPTTPQETVTG--KLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQ 966
Query: 1086 -PTPEEP-TSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEP 1143
P P +P TS T + P +PA ++P +E +PAA P+ A A V E
Sbjct: 967 APAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPK--AEQAPTVKRTETE 1024
Query: 1144 AFPAPAVPTPEESASAAVAV-PTP-EESASPAAAVP 1177
P P + +A AV PT E+S P + P
Sbjct: 1025 KKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCP 1060
Score = 64.7 bits (156), Expect = 6e-10
Identities = 77/344 (22%), Positives = 122/344 (35%), Gaps = 22/344 (6%)
Query: 985 EEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAA 1044
+E + + +P + PA P + +A P P P P PPP P P
Sbjct: 2369 QEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLP 2428
Query: 1045 AVPTPEEPT---SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTP 1101
PT +PT V +P +P T E T+ + P A P P
Sbjct: 2429 P-PTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVP 2487
Query: 1102 EEPTS-PAAAVPTPE-EPASPAAAVPTPEEPASPAAA-VPT---PEEPAFPAPAVPTPEE 1155
+P+S P+ V T EP+ P A P P P P PT P+ + T
Sbjct: 2488 PKPSSIPSGLVFTHRPEPSKPPIA-PKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNL 2546
Query: 1156 SASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEF 1215
SA +P+P SP + +P S S + P+ P + A+ T
Sbjct: 2547 VTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPL 2606
Query: 1216 TSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPT---SSAAAVLTPEELSSPAA 1272
SP+ + + E S+ P A +P E T S A + +++P++
Sbjct: 2607 GSPSKDLVSVEPVFSVV--------PPVTAVEIPISSEQTFYISGALQTFSATPVTAPSS 2658
Query: 1273 SVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTP 1316
P + E ++ + P+ +++I P P
Sbjct: 2659 FQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPPEP 2702
Score = 58.2 bits (139), Expect = 6e-08
Identities = 99/497 (19%), Positives = 164/497 (32%), Gaps = 86/497 (17%)
Query: 916 VPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPV 975
+PEG AA AA A + + GM A E I ++ G P+G V
Sbjct: 12 LPEGLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSV 71
Query: 976 TPAT----TVHAPEEPDTA-----AVRVSTPEEPASPAAAVPTPEEPTSPAAAVP----- 1021
PA ++H +E D++ + R P PA P + + +P
Sbjct: 72 PPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPS 131
Query: 1022 ----------TPEEPTSPAAAVPPPEEPTSPAAAV-----------------PTPEEPTS 1054
T + ++ +P + +AV + EE T
Sbjct: 132 TISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTK 191
Query: 1055 PAAAVPTPEEPTSPAAAVPTPEEPTSP------AAAVPTPEEPTSPAAAVPTPEEPTSPA 1108
V + P ++P P P ++ T + + PE+ S
Sbjct: 192 KQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQP 251
Query: 1109 AAVPTP-----EEPASPAAAVPTPEE---PASPAAAVPTPE--EPAFPAPAVPTPEESAS 1158
P + P + A +P + P + A + E +P+ P+P+ P ++
Sbjct: 252 PGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTP 311
Query: 1159 AAVAVPTP-EESASPAAAVPTPAESASFAAVVA----TLEEPTSPAASVPTPAAMVATLE 1213
P E + P A P PA+ + +A T++ P P + PA + +
Sbjct: 312 GKPPAQQPGHEKSQPGPAKP-PAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAK 370
Query: 1214 EFTSPAAS-VPTSEEPASLA-----------AAVSNPEEPTS-------PAAAVPTLEEP 1254
S P+SE+P A A P +P + P A P L+ P
Sbjct: 371 PPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSP 430
Query: 1255 TSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVP 1314
+ TP + P P + A P + P P + +P P P P
Sbjct: 431 AKAPGPTKTPVQQPGPG---KIPAQQAGPGKTSAQQTGPTKPPSQLPGP-AKPPPQQPGP 486
Query: 1315 TPEVPAIPAAAVPPMEE 1331
P P +A PP ++
Sbjct: 487 AKPPPQQPGSAKPPSQQ 503
Score = 45.4 bits (106), Expect = 4e-04
Identities = 100/498 (20%), Positives = 182/498 (36%), Gaps = 74/498 (14%)
Query: 879 PHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAA 938
P EDI+ +S + E ++ + + S E + A ++ EE
Sbjct: 2025 PQEDIVSSSFIIPESHEIV----------DLGTMVTSTEEERKLLDADAAYEEL------ 2068
Query: 939 AITQEGMSAVAGFSPEWAALA--ITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVST 996
+ ++ M G SP A + +T + D P+ +T + A T++ +S
Sbjct: 2069 -MKRQQMQLTPGSSPTQAPIGEDMTESTMDFDRMPDASLTSSVLSGASLTDSTSSATLSI 2127
Query: 997 PEEPASPAAAVPTPE------------EPTSPAAAVPTPEEPTSPAAAVPPPEEP--TSP 1042
P+ + + E E + + + T EP+ A +VPP + P TS
Sbjct: 2128 PDVKITQHFSTEEIEDEYVTDYTREIQEIIAHESLILTYSEPSESATSVPPSDTPSLTSS 2187
Query: 1043 AAAVPTPE--EPTSPAAAVPTP-EEPTSPAAAVPTPEEPTS----PAAAVPTPEEPTSPA 1095
++V T + P + ++ T EP EE +S P + + PEE +
Sbjct: 2188 VSSVCTTDSSSPITTLDSITTVYTEPVDMITKFEDSEEISSSTYFPGSIIDYPEEISVSL 2247
Query: 1096 AAVPTPEEPTSPAAAVPTPEEPASP--AAAVPTPEEPASPAAAVP---TPEEPAFPA--- 1147
P+ S V + + AS + VP PE P + + + ++P A
Sbjct: 2248 DRTAPPDGRASADHIVISLSDMASSIIESVVPKPEGPVADTVSTDLLISEKDPVKKAKKE 2307
Query: 1148 --------------PAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLE 1193
E ++++ + S A+P + ++
Sbjct: 2308 TGNGIILEVLEAYRDKKELEAERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGETF 2367
Query: 1194 EPTSPAASVPTPAAMVATLEEFTSP---AASVPTSEEPASLAAAVSNPEEPTSPAAAVPT 1250
PA+ +P+ + V++L P ++S+ S +P P P P P
Sbjct: 2368 GQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPP-PPPPPPPPPPPPPPPPPPP 2426
Query: 1251 LEEPTSSAAAVLTPEELSSPAASVPTPEEPASPA-AAVSNLEEPA-SPAAAVPTPEVAAI 1308
L PTS +L ++L +V +P A+P AV+ LE A + +P +
Sbjct: 2427 LPPPTSPKPTILPKKKL-----TVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTT 2481
Query: 1309 PAASVPTPEVPAIPAAAV 1326
VP P+ +IP+ V
Sbjct: 2482 APPPVP-PKPSSIPSGLV 2498
Score = 45.1 bits (105), Expect = 5e-04
Identities = 155/767 (20%), Positives = 256/767 (33%), Gaps = 143/767 (18%)
Query: 660 LTDVTSGPEVEVLYESNLLTDEIHLESGNVTVNQENNSLTSMGNVVTCELSVEKVCDEDG 719
+TD T + + +ES +LT ES + SLTS SV VC D
Sbjct: 2146 VTDYTREIQEIIAHESLILTYSEPSESATSVPPSDTPSLTS---------SVSSVCTTDS 2196
Query: 720 EAK--ELDYQATLL--------------EDQAPAHFHRN---FPEQVFQDLQRKSPESEI 760
+ LD T+ E + +F + +PE++ L R +P
Sbjct: 2197 SSPITTLDSITTVYTEPVDMITKFEDSEEISSSTYFPGSIIDYPEEISVSLDRTAPPDGR 2256
Query: 761 LSL-HLLVEELRLNPDGVETVNDTKPELNVASSEGGEMERRDSD---------------S 804
S H+++ + +E+V KPE VA + ++ + D
Sbjct: 2257 ASADHIVISLSDMASSIIESVVP-KPEGPVADTVSTDLLISEKDPVKKAKKETGNGIILE 2315
Query: 805 FLNIFPEKQVTKAGNTEPVLEEWIPVLQRPSRTAAVPTVKDALDAALPSPEE-GTSIAAV 863
L + +K+ +A T+ L E + PS A+P + S E G A
Sbjct: 2316 VLEAYRDKKELEAERTKSSLSETV-FDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPAS 2374
Query: 864 PAPEGTAVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAV 923
P G+ V++L P +S+ + P P +P T+
Sbjct: 2375 QLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPK 2434
Query: 924 AA--------VSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPV 975
V+SP TA + A+T +AV + +P+T T PV
Sbjct: 2435 PTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNG--------LPVTRICTTAPPPV 2486
Query: 976 TPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPT-PEEPTSPAAAVPTPEEPTSPAAAVP 1034
P P + V PE P A P P+ PT+ +PT +
Sbjct: 2487 PPK-----PSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSS 2541
Query: 1035 PPEE-PTSPAAAVPTPEEPTSPAAAVPTP---EEPTSPAAAVPTPEEPTSPAAAVPTPEE 1090
TS +P+P P SP + +P + T + P EP +P + +
Sbjct: 2542 MTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAI 2601
Query: 1091 PTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTP---EEPASPAAAVPTPEEPAFPA 1147
+ P + P+ +V P AV P E+ + A+ T F A
Sbjct: 2602 TSWPLGS------PSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQT-----FSA 2650
Query: 1148 PAVPTPEESASAAVAVP---TPEESASPAAAVPTPAESASFAAVVATLE-EPTS------ 1197
V P +A +V T E S + +A + A S +++ T+ EP +
Sbjct: 2651 TPVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPPEPLALDNIHL 2710
Query: 1198 --PAASVPTPAAMVATLEEF-TSPAASVPTSEEPASLAAAVSNPEE-------------- 1240
P +V + + T P V T+++ L+A+ + +
Sbjct: 2711 EKPQYKEDGKLQLVGDVIDLRTVPKVEVKTTDKCIDLSASTMDVKRQITANEVYGKQISA 2770
Query: 1241 ----------------PTSPAAAVPTLEEPTSSAA-------------AVLTPEELSSPA 1271
P S A T T+SA+ A+ TP +L++
Sbjct: 2771 VQPSIINLSVTSSIVTPVSLATETVTFVTCTASASYTTGTESLVGAEHAMTTPLQLTTSK 2830
Query: 1272 ASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEV 1318
+ P P+ ++ E P + + P V V P V
Sbjct: 2831 HAEPPYRIPSDQVFPIAREEAPINLSLGTPAHAVTLAITKPVTVPPV 2877
Score = 43.5 bits (101), Expect = 0.001
Identities = 60/272 (22%), Positives = 106/272 (38%), Gaps = 20/272 (7%)
Query: 1076 EEPTSPAAAVPTPEEPTSPAAAVPTPEEP--TSPAAAVPTPEE--PASPAAAVPTP-EEP 1130
+E + + + T EP+ A +VP + P TS ++V T + P + ++ T EP
Sbjct: 2154 QEIIAHESLILTYSEPSESATSVPPSDTPSLTSSVSSVCTTDSSSPITTLDSITTVYTEP 2213
Query: 1131 ASPAAAVPTPEEPA----FPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFA 1186
EE + FP + PEE + + P+ AS V + ++ AS +
Sbjct: 2214 VDMITKFEDSEEISSSTYFPGSIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMAS-S 2272
Query: 1187 AVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPE---EPTS 1243
+ + + +P P A + +++ + L A E E T
Sbjct: 2273 IIESVVPKPEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTK 2332
Query: 1244 PAAAVPTLEEPTSSAAAVLTPEELSSP---AASVPTPEEPASP----AAAVSNLEEPASP 1296
+ + + P SS A+ E+LS+ + E+PAS + +VS+L P
Sbjct: 2333 SSLSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRP 2392
Query: 1297 AAAVPTPEVAAIPAASVPTPEVPAIPAAAVPP 1328
+ +++A P P P P P PP
Sbjct: 2393 FFRSSSLDISAQPPPPPPPPPPPPPPPPPPPP 2424
Score = 33.9 bits (76), Expect = 1.2
Identities = 67/309 (21%), Positives = 98/309 (31%), Gaps = 26/309 (8%)
Query: 1010 PEEPTSPAAA-VPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSP 1068
P P+ P A+ +P P E +S AVPP V E+ A E+
Sbjct: 1126 PPAPSGPKASPMPVPTESSSQKTAVPP------QVKLVKKQEQEVKTEAEKVILEKVKET 1179
Query: 1069 AAAVPTPEEPTSPAAAVPTPEEPTSPAA---AVPTPEEPTSPAAAVPTPEEPASP--AAA 1123
+ P T+ + E +A P PEE E P
Sbjct: 1180 LSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEK 1239
Query: 1124 VPTPEE-PASPAAAVPTPEEPAFP--APAVPTPEESASAAVAVPTPEESASP-------A 1173
PTPE+ P A PEE V EE VA T +E P
Sbjct: 1240 KPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLP 1299
Query: 1174 AAVPTPAESASFAAVVATLEEPTSPAASVP---TPAAMVATLEEFTSPAASVPTSEEPAS 1230
+ P E+P P + P P E+ S +S + P
Sbjct: 1300 SGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQG 1359
Query: 1231 LAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPAS-PAAAVSN 1289
L+ + + +S +P+L ++ S +S +P + A + +S
Sbjct: 1360 LSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSI 1419
Query: 1290 LEEPASPAA 1298
LE AS A
Sbjct: 1420 LEAQASTLA 1428
Score = 33.1 bits (74), Expect = 2.0
Identities = 57/279 (20%), Positives = 92/279 (32%), Gaps = 26/279 (9%)
Query: 884 LVASIVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQE 943
+V S V ++ED T + + R T +V SV P + +
Sbjct: 3440 IVDSGVQTDDEDATDRSYVSRRRRTKKSVDTSVQTDDEDQDEWDMPTRSRRKARVGKYGD 3499
Query: 944 GMSAVAGFSPEWAALAITVPITEEDGTPEGPVTPATT--VHAPEEPDTAAVRVSTPEEPA 1001
M+ P +I V E PV T + A + ++ + E
Sbjct: 3500 SMTEADKTKPLSKVSSIAVQTVAEISVQTEPVGTIRTPSIRARVDAKVEIIKHISAPEKT 3559
Query: 1002 SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPT 1061
++ E S + P +A PP ++ + + +
Sbjct: 3560 YKGGSLGCQTEADSDT------QSPQYLSATSPPKDKKRPTPLEIGYSSHLRADSTVQLA 3613
Query: 1062 PEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASP- 1120
P P SP +P P SP A+ + P P P++ + P++ P
Sbjct: 3614 PSPPKSPKVLY-SPISPLSPGKALESAFVPYEK----PLPDDIS--------PQKVLHPD 3660
Query: 1121 AAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASA 1159
A VP PASP A + P P PT +ES+ A
Sbjct: 3661 MAKVP----PASPKTAKMMQRSMSDPKPLSPTADESSRA 3695
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 103 bits (256), Expect = 2e-21
Identities = 109/467 (23%), Positives = 170/467 (36%), Gaps = 75/467 (16%)
Query: 960 ITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAA 1019
+T P+ ++ GT + PV P T P +P A + P++ P P+ P
Sbjct: 338 LTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGV 397
Query: 1020 VPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEP--TSPAAAVPTPEEPTSPAAAVPTPEE 1077
TP + PA PP ++ +P P ++P SPA A + P P +
Sbjct: 398 GKTPAQQPGPAK--PPTQQVGTPK---PLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQ 452
Query: 1078 PTSPAAAVPTPEEPTSPAAAVPTPEEPT--SPAAAVPTPEEPASPAAAVPTPEEPASPAA 1135
P PT P + +P P +P P A P P++P S A P ++P S
Sbjct: 453 QAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGS---AKPPSQQPGS--- 506
Query: 1136 AVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVAT---- 1191
T P P PA P+P++ S P SA P+A P+PA+ ++ +
Sbjct: 507 ---TKPPPQQPGPAKPSPQQPGSTKPPSQQPG-SAKPSAQQPSPAKPSAQQSTKPVSQTG 562
Query: 1192 ----LEEPT-SPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVS---------- 1236
L+ PT SP+A P + T+ + + E A+
Sbjct: 563 SGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCG 622
Query: 1237 -NPEEPTSPA------------------AAVPTLEEPTSSAAAVLTPEELS--SPAASVP 1275
NP + A VP+ +P A V T +S SP
Sbjct: 623 FNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQT 682
Query: 1276 TPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPMEEVSPI 1335
+P++ A+P +S EP P V P + P+A P + PP E
Sbjct: 683 SPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEP---- 738
Query: 1336 GVPFLGVSAHTDSVPISEEG-------TPVLEEASSTGMWIKEDLDS 1375
V + D P++++ P + SS+ K D+ S
Sbjct: 739 -----SVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPS 780
Score = 85.5 bits (210), Expect = 3e-16
Identities = 86/377 (22%), Positives = 134/377 (35%), Gaps = 40/377 (10%)
Query: 966 EEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAA------- 1018
++DGTP+ + + P T + P + A +P + + P
Sbjct: 231 QQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVR 290
Query: 1019 ------AVPTPEEPT--SPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEP---TS 1067
++P+P +P P PP ++P E + P A P P +P T
Sbjct: 291 GESVKPSLPSPSKPPIQQPTPGKPPAQQP---------GHEKSQPGPAKP-PAQPSGLTK 340
Query: 1068 PAAAVP-TPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPT 1126
P A P T + P P P +P PA P++ P P+ A P T
Sbjct: 341 PLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKT 400
Query: 1127 PEEPASPAAAVPTPEEPAFPAPAVPTP--EESASAAVAVPTPEESASPAAAVPTPAESAS 1184
P + P A P ++ P P P + A A TP + P PA+ A
Sbjct: 401 PAQ--QPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPG---KIPAQQAG 455
Query: 1185 FAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSP 1244
A PT P + +P PA P P S +P S + P P P
Sbjct: 456 PGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKP-PPQQP 514
Query: 1245 AAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPT-- 1302
A P+ ++P S+ P + P+A P+P +P++ + + + PT
Sbjct: 515 GPAKPSPQQPGSTKPPSQQPGS-AKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVS 573
Query: 1303 PEVAAIPAASVPTPEVP 1319
P P+ +P P
Sbjct: 574 PSAKQPPSQGLPKTICP 590
Score = 81.3 bits (199), Expect = 6e-15
Identities = 104/422 (24%), Positives = 164/422 (38%), Gaps = 37/422 (8%)
Query: 927 SSPE---ETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHA 983
SSP+ +TAP + + SP+ A P + PE P P V
Sbjct: 655 SSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDA----APKQDLSKAPE-PKKPPPLVKQ 709
Query: 984 PEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTP---EEPTSPAAAVPPPEEPT 1040
P + + + P E S + P P+EP+ P+ P ++P P V P +
Sbjct: 710 PTLHGSPSAKAKQPPEADSLSKPAP-PKEPSVPSEQDKAPVADDKPKQPKM-VKPTTDLV 767
Query: 1041 SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSP--AAAV 1098
S ++A P+ P+S + EE T+P P + P+ + P E SP + A+
Sbjct: 768 SSSSATTKPDIPSSKVQS--QAEEKTTP----PLKTDSAKPSQSFPPTGEKVSPFDSKAI 821
Query: 1099 PTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAA----VPTPEEPAFPAPAVPTPE 1154
P P S + P P + V ++ P A P P+ P + P
Sbjct: 822 PRPAS-DSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPG 880
Query: 1155 ESASAAVAVPTPEESASPAAAVPTPAESASFAAVV-ATLEEPTSPAASVPTPAAMVATLE 1213
+A VPTP++S P + S + ++ A +PT+P +V T
Sbjct: 881 PRPTAGQTVPTPQQSPKPQE--QSRRFSLNLGSITDAPKSQPTTPQETV-TGKLFGFGAS 937
Query: 1214 EFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAAS 1273
F+ + + T+ +P + + +PA + P PTS T + +PA S
Sbjct: 938 IFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQP----PTSQGPPKSTGQAPPAPAKS 993
Query: 1274 VPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPME-EV 1332
+P +E +PAA LE A A V E P + + A P AV P + E
Sbjct: 994 IPVKKETKAPAA--EKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEK 1051
Query: 1333 SP 1334
SP
Sbjct: 1052 SP 1053
Score = 74.7 bits (182), Expect = 6e-13
Identities = 101/439 (23%), Positives = 166/439 (37%), Gaps = 65/439 (14%)
Query: 904 PERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVP 963
P+ T P T S A + P++T+P AA Q+ A P P
Sbjct: 659 PKLKTAPVTTTS-----AVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPP--------P 705
Query: 964 ITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTP---EEPTSPAAAV 1020
+ ++ P +P+ P E D+ + + + P+EP+ P+ P ++P P
Sbjct: 706 LVKQ---PTLHGSPSAKAKQPPEADSLS-KPAPPKEPSVPSEQDKAPVADDKPKQPKMVK 761
Query: 1021 PTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTS 1080
PT + +S ++A P+ P+S + EE T+P P + P+ + P E S
Sbjct: 762 PTTDLVSS-SSATTKPDIPSSKVQS--QAEEKTTP----PLKTDSAKPSQSFPPTGEKVS 814
Query: 1081 P--AAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAV----PTPEEPASPA 1134
P + A+P P S + P P + V ++ P A P P+ P
Sbjct: 815 PFDSKAIPRPASD-SKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPK 873
Query: 1135 AAVPTPEEPAFPA-PAVPTPEESASAAVAVPTPEESA------------SPAAAVPTPAE 1181
+ PTP P A VPTP++S P P+E + +P + TP E
Sbjct: 874 GS-PTPPGPRPTAGQTVPTPQQS-------PKPQEQSRRFSLNLGSITDAPKSQPTTPQE 925
Query: 1182 SAS-----FAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPT-SEEPASLAAAV 1235
+ + F A + + A P P + +P P S+ P S
Sbjct: 926 TVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGP----GAPMKQAPAPSQPPTSQGPPK 981
Query: 1236 SNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPAS 1295
S + P +PA ++P +E + AA L P+ +P E+ P +L
Sbjct: 982 STGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQ 1041
Query: 1296 PAAAVPTPEVAAIPAASVP 1314
A E + P ++ P
Sbjct: 1042 KAVLPTKLEKSPKPESTCP 1060
Score = 69.3 bits (168), Expect = 2e-11
Identities = 88/387 (22%), Positives = 135/387 (34%), Gaps = 63/387 (16%)
Query: 1002 SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPT 1061
+P + P P+ T+P + +SP P++ +P + EP P V
Sbjct: 651 APVPSSPQPKLKTAPVTTTSAVSK-SSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQ 709
Query: 1062 PEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTP---EEPTSPAAAVPTPEEPA 1118
P SP+A P E S + P P+EP+ P+ P ++P P PT +
Sbjct: 710 PTLHGSPSAKAKQPPEADSLSKPAP-PKEPSVPSEQDKAPVADDKPKQPKMVKPT-TDLV 767
Query: 1119 SPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASP--AAAV 1176
S ++A P+ P+S + EE P P +SA + + P E SP + A+
Sbjct: 768 SSSSATTKPDIPSSKVQS--QAEEKTTP----PLKTDSAKPSQSFPPTGEKVSPFDSKAI 821
Query: 1177 PTPAESASFAA---------------VVATLEEPT------------------SPAASVP 1203
P PA + + V EEP SP P
Sbjct: 822 PRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGP 881
Query: 1204 TPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPE-EPTSP-----------AAAVPTL 1251
P A SP + +L + P+ +PT+P A++ +
Sbjct: 882 RPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQ 941
Query: 1252 EEPTSSAAAVLTPEELSSPAA---SVPTPEE-PASPAAAVSNLEEPASPAAAVPTPEVAA 1307
S A P S P A P P + P S S + P +PA ++P +
Sbjct: 942 ASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETK 1001
Query: 1308 IPAASVPTPEVPAIPAAAVPPMEEVSP 1334
PAA P+ P E+ P
Sbjct: 1002 APAAEKLEPKAEQAPTVKRTETEKKPP 1028
Score = 65.9 bits (159), Expect = 3e-10
Identities = 95/396 (23%), Positives = 153/396 (38%), Gaps = 53/396 (13%)
Query: 810 PEKQVTKAGNTE--PVLEEWIPVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPE 867
P++ ++KA + P L + + PS A P D+L P E +VP+ +
Sbjct: 690 PKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEP-----SVPSEQ 744
Query: 868 GTAVVAALVPFPHEDI-----LVASIVSLEEEDVTAAAVS--APERATVPAVTVSVPEGT 920
A VA P + + LV+S + + D+ ++ V A E+ T P T S
Sbjct: 745 DKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDS----- 799
Query: 921 AAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTPATT 980
+ P ++ P ++ A+ + + ++ P +E G + V P
Sbjct: 800 ------AKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQ--VDP--- 848
Query: 981 VHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAA-AVPTPEEPTSP---------- 1029
V EEP A ++S + PTP P A VPTP++ P
Sbjct: 849 VQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLN 908
Query: 1030 --AAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAV-- 1085
+ P +PT+P V + A++ + A P P + P A +
Sbjct: 909 LGSITDAPKSQPTTPQETVTG--KLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQ 966
Query: 1086 -PTPEEP-TSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEP 1143
P P +P TS T + P +PA ++P +E +PAA P+ A A V E
Sbjct: 967 APAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPK--AEQAPTVKRTETE 1024
Query: 1144 AFPAPAVPTPEESASAAVAV-PTP-EESASPAAAVP 1177
P P + +A AV PT E+S P + P
Sbjct: 1025 KKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCP 1060
Score = 64.7 bits (156), Expect = 6e-10
Identities = 77/344 (22%), Positives = 122/344 (35%), Gaps = 22/344 (6%)
Query: 985 EEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAA 1044
+E + + +P + PA P + +A P P P P PPP P P
Sbjct: 2369 QEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLP 2428
Query: 1045 AVPTPEEPT---SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTP 1101
PT +PT V +P +P T E T+ + P A P P
Sbjct: 2429 P-PTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVP 2487
Query: 1102 EEPTS-PAAAVPTPE-EPASPAAAVPTPEEPASPAAA-VPT---PEEPAFPAPAVPTPEE 1155
+P+S P+ V T EP+ P A P P P P PT P+ + T
Sbjct: 2488 PKPSSIPSGLVFTHRPEPSKPPIA-PKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNL 2546
Query: 1156 SASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEF 1215
SA +P+P SP + +P S S + P+ P + A+ T
Sbjct: 2547 VTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPL 2606
Query: 1216 TSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPT---SSAAAVLTPEELSSPAA 1272
SP+ + + E S+ P A +P E T S A + +++P++
Sbjct: 2607 GSPSKDLVSVEPVFSVV--------PPVTAVEIPISSEQTFYISGALQTFSATPVTAPSS 2658
Query: 1273 SVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTP 1316
P + E ++ + P+ +++I P P
Sbjct: 2659 FQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPPEP 2702
Score = 58.2 bits (139), Expect = 6e-08
Identities = 99/497 (19%), Positives = 164/497 (32%), Gaps = 86/497 (17%)
Query: 916 VPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPV 975
+PEG AA AA A + + GM A E I ++ G P+G V
Sbjct: 12 LPEGLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSV 71
Query: 976 TPAT----TVHAPEEPDTA-----AVRVSTPEEPASPAAAVPTPEEPTSPAAAVP----- 1021
PA ++H +E D++ + R P PA P + + +P
Sbjct: 72 PPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPS 131
Query: 1022 ----------TPEEPTSPAAAVPPPEEPTSPAAAV-----------------PTPEEPTS 1054
T + ++ +P + +AV + EE T
Sbjct: 132 TISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTK 191
Query: 1055 PAAAVPTPEEPTSPAAAVPTPEEPTSP------AAAVPTPEEPTSPAAAVPTPEEPTSPA 1108
V + P ++P P P ++ T + + PE+ S
Sbjct: 192 KQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQP 251
Query: 1109 AAVPTP-----EEPASPAAAVPTPEE---PASPAAAVPTPE--EPAFPAPAVPTPEESAS 1158
P + P + A +P + P + A + E +P+ P+P+ P ++
Sbjct: 252 PGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTP 311
Query: 1159 AAVAVPTP-EESASPAAAVPTPAESASFAAVVA----TLEEPTSPAASVPTPAAMVATLE 1213
P E + P A P PA+ + +A T++ P P + PA + +
Sbjct: 312 GKPPAQQPGHEKSQPGPAKP-PAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAK 370
Query: 1214 EFTSPAAS-VPTSEEPASLA-----------AAVSNPEEPTS-------PAAAVPTLEEP 1254
S P+SE+P A A P +P + P A P L+ P
Sbjct: 371 PPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSP 430
Query: 1255 TSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVP 1314
+ TP + P P + A P + P P + +P P P P
Sbjct: 431 AKAPGPTKTPVQQPGPG---KIPAQQAGPGKTSAQQTGPTKPPSQLPGP-AKPPPQQPGP 486
Query: 1315 TPEVPAIPAAAVPPMEE 1331
P P +A PP ++
Sbjct: 487 AKPPPQQPGSAKPPSQQ 503
Score = 45.4 bits (106), Expect = 4e-04
Identities = 100/498 (20%), Positives = 182/498 (36%), Gaps = 74/498 (14%)
Query: 879 PHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAA 938
P EDI+ +S + E ++ + + S E + A ++ EE
Sbjct: 2025 PQEDIVSSSFIIPESHEIV----------DLGTMVTSTEEERKLLDADAAYEEL------ 2068
Query: 939 AITQEGMSAVAGFSPEWAALA--ITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVST 996
+ ++ M G SP A + +T + D P+ +T + A T++ +S
Sbjct: 2069 -MKRQQMQLTPGSSPTQAPIGEDMTESTMDFDRMPDASLTSSVLSGASLTDSTSSATLSI 2127
Query: 997 PEEPASPAAAVPTPE------------EPTSPAAAVPTPEEPTSPAAAVPPPEEP--TSP 1042
P+ + + E E + + + T EP+ A +VPP + P TS
Sbjct: 2128 PDVKITQHFSTEEIEDEYVTDYTREIQEIIAHESLILTYSEPSESATSVPPSDTPSLTSS 2187
Query: 1043 AAAVPTPE--EPTSPAAAVPTP-EEPTSPAAAVPTPEEPTS----PAAAVPTPEEPTSPA 1095
++V T + P + ++ T EP EE +S P + + PEE +
Sbjct: 2188 VSSVCTTDSSSPITTLDSITTVYTEPVDMITKFEDSEEISSSTYFPGSIIDYPEEISVSL 2247
Query: 1096 AAVPTPEEPTSPAAAVPTPEEPASP--AAAVPTPEEPASPAAAVP---TPEEPAFPA--- 1147
P+ S V + + AS + VP PE P + + + ++P A
Sbjct: 2248 DRTAPPDGRASADHIVISLSDMASSIIESVVPKPEGPVADTVSTDLLISEKDPVKKAKKE 2307
Query: 1148 --------------PAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLE 1193
E ++++ + S A+P + ++
Sbjct: 2308 TGNGIILEVLEAYRDKKELEAERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGETF 2367
Query: 1194 EPTSPAASVPTPAAMVATLEEFTSP---AASVPTSEEPASLAAAVSNPEEPTSPAAAVPT 1250
PA+ +P+ + V++L P ++S+ S +P P P P P
Sbjct: 2368 GQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPP-PPPPPPPPPPPPPPPPPPP 2426
Query: 1251 LEEPTSSAAAVLTPEELSSPAASVPTPEEPASPA-AAVSNLEEPA-SPAAAVPTPEVAAI 1308
L PTS +L ++L +V +P A+P AV+ LE A + +P +
Sbjct: 2427 LPPPTSPKPTILPKKKL-----TVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTT 2481
Query: 1309 PAASVPTPEVPAIPAAAV 1326
VP P+ +IP+ V
Sbjct: 2482 APPPVP-PKPSSIPSGLV 2498
Score = 45.1 bits (105), Expect = 5e-04
Identities = 155/767 (20%), Positives = 256/767 (33%), Gaps = 143/767 (18%)
Query: 660 LTDVTSGPEVEVLYESNLLTDEIHLESGNVTVNQENNSLTSMGNVVTCELSVEKVCDEDG 719
+TD T + + +ES +LT ES + SLTS SV VC D
Sbjct: 2146 VTDYTREIQEIIAHESLILTYSEPSESATSVPPSDTPSLTS---------SVSSVCTTDS 2196
Query: 720 EAK--ELDYQATLL--------------EDQAPAHFHRN---FPEQVFQDLQRKSPESEI 760
+ LD T+ E + +F + +PE++ L R +P
Sbjct: 2197 SSPITTLDSITTVYTEPVDMITKFEDSEEISSSTYFPGSIIDYPEEISVSLDRTAPPDGR 2256
Query: 761 LSL-HLLVEELRLNPDGVETVNDTKPELNVASSEGGEMERRDSD---------------S 804
S H+++ + +E+V KPE VA + ++ + D
Sbjct: 2257 ASADHIVISLSDMASSIIESVVP-KPEGPVADTVSTDLLISEKDPVKKAKKETGNGIILE 2315
Query: 805 FLNIFPEKQVTKAGNTEPVLEEWIPVLQRPSRTAAVPTVKDALDAALPSPEE-GTSIAAV 863
L + +K+ +A T+ L E + PS A+P + S E G A
Sbjct: 2316 VLEAYRDKKELEAERTKSSLSETV-FDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPAS 2374
Query: 864 PAPEGTAVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAV 923
P G+ V++L P +S+ + P P +P T+
Sbjct: 2375 QLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPK 2434
Query: 924 AA--------VSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPV 975
V+SP TA + A+T +AV + +P+T T PV
Sbjct: 2435 PTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNG--------LPVTRICTTAPPPV 2486
Query: 976 TPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPT-PEEPTSPAAAVPTPEEPTSPAAAVP 1034
P P + V PE P A P P+ PT+ +PT +
Sbjct: 2487 PPK-----PSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSS 2541
Query: 1035 PPEE-PTSPAAAVPTPEEPTSPAAAVPTP---EEPTSPAAAVPTPEEPTSPAAAVPTPEE 1090
TS +P+P P SP + +P + T + P EP +P + +
Sbjct: 2542 MTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAI 2601
Query: 1091 PTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTP---EEPASPAAAVPTPEEPAFPA 1147
+ P + P+ +V P AV P E+ + A+ T F A
Sbjct: 2602 TSWPLGS------PSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQT-----FSA 2650
Query: 1148 PAVPTPEESASAAVAVP---TPEESASPAAAVPTPAESASFAAVVATLE-EPTS------ 1197
V P +A +V T E S + +A + A S +++ T+ EP +
Sbjct: 2651 TPVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPPEPLALDNIHL 2710
Query: 1198 --PAASVPTPAAMVATLEEF-TSPAASVPTSEEPASLAAAVSNPEE-------------- 1240
P +V + + T P V T+++ L+A+ + +
Sbjct: 2711 EKPQYKEDGKLQLVGDVIDLRTVPKVEVKTTDKCIDLSASTMDVKRQITANEVYGKQISA 2770
Query: 1241 ----------------PTSPAAAVPTLEEPTSSAA-------------AVLTPEELSSPA 1271
P S A T T+SA+ A+ TP +L++
Sbjct: 2771 VQPSIINLSVTSSIVTPVSLATETVTFVTCTASASYTTGTESLVGAEHAMTTPLQLTTSK 2830
Query: 1272 ASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEV 1318
+ P P+ ++ E P + + P V V P V
Sbjct: 2831 HAEPPYRIPSDQVFPIAREEAPINLSLGTPAHAVTLAITKPVTVPPV 2877
Score = 43.5 bits (101), Expect = 0.001
Identities = 60/272 (22%), Positives = 106/272 (38%), Gaps = 20/272 (7%)
Query: 1076 EEPTSPAAAVPTPEEPTSPAAAVPTPEEP--TSPAAAVPTPEE--PASPAAAVPTP-EEP 1130
+E + + + T EP+ A +VP + P TS ++V T + P + ++ T EP
Sbjct: 2154 QEIIAHESLILTYSEPSESATSVPPSDTPSLTSSVSSVCTTDSSSPITTLDSITTVYTEP 2213
Query: 1131 ASPAAAVPTPEEPA----FPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFA 1186
EE + FP + PEE + + P+ AS V + ++ AS +
Sbjct: 2214 VDMITKFEDSEEISSSTYFPGSIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMAS-S 2272
Query: 1187 AVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPE---EPTS 1243
+ + + +P P A + +++ + L A E E T
Sbjct: 2273 IIESVVPKPEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTK 2332
Query: 1244 PAAAVPTLEEPTSSAAAVLTPEELSSP---AASVPTPEEPASP----AAAVSNLEEPASP 1296
+ + + P SS A+ E+LS+ + E+PAS + +VS+L P
Sbjct: 2333 SSLSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRP 2392
Query: 1297 AAAVPTPEVAAIPAASVPTPEVPAIPAAAVPP 1328
+ +++A P P P P P PP
Sbjct: 2393 FFRSSSLDISAQPPPPPPPPPPPPPPPPPPPP 2424
Score = 33.9 bits (76), Expect = 1.2
Identities = 67/309 (21%), Positives = 98/309 (31%), Gaps = 26/309 (8%)
Query: 1010 PEEPTSPAAA-VPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSP 1068
P P+ P A+ +P P E +S AVPP V E+ A E+
Sbjct: 1126 PPAPSGPKASPMPVPTESSSQKTAVPP------QVKLVKKQEQEVKTEAEKVILEKVKET 1179
Query: 1069 AAAVPTPEEPTSPAAAVPTPEEPTSPAA---AVPTPEEPTSPAAAVPTPEEPASP--AAA 1123
+ P T+ + E +A P PEE E P
Sbjct: 1180 LSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEK 1239
Query: 1124 VPTPEE-PASPAAAVPTPEEPAFP--APAVPTPEESASAAVAVPTPEESASP-------A 1173
PTPE+ P A PEE V EE VA T +E P
Sbjct: 1240 KPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLP 1299
Query: 1174 AAVPTPAESASFAAVVATLEEPTSPAASVP---TPAAMVATLEEFTSPAASVPTSEEPAS 1230
+ P E+P P + P P E+ S +S + P
Sbjct: 1300 SGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQG 1359
Query: 1231 LAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPAS-PAAAVSN 1289
L+ + + +S +P+L ++ S +S +P + A + +S
Sbjct: 1360 LSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSI 1419
Query: 1290 LEEPASPAA 1298
LE AS A
Sbjct: 1420 LEAQASTLA 1428
Score = 33.1 bits (74), Expect = 2.0
Identities = 57/279 (20%), Positives = 92/279 (32%), Gaps = 26/279 (9%)
Query: 884 LVASIVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQE 943
+V S V ++ED T + + R T +V SV P + +
Sbjct: 3440 IVDSGVQTDDEDATDRSYVSRRRRTKKSVDTSVQTDDEDQDEWDMPTRSRRKARVGKYGD 3499
Query: 944 GMSAVAGFSPEWAALAITVPITEEDGTPEGPVTPATT--VHAPEEPDTAAVRVSTPEEPA 1001
M+ P +I V E PV T + A + ++ + E
Sbjct: 3500 SMTEADKTKPLSKVSSIAVQTVAEISVQTEPVGTIRTPSIRARVDAKVEIIKHISAPEKT 3559
Query: 1002 SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPT 1061
++ E S + P +A PP ++ + + +
Sbjct: 3560 YKGGSLGCQTEADSDT------QSPQYLSATSPPKDKKRPTPLEIGYSSHLRADSTVQLA 3613
Query: 1062 PEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASP- 1120
P P SP +P P SP A+ + P P P++ + P++ P
Sbjct: 3614 PSPPKSPKVLY-SPISPLSPGKALESAFVPYEK----PLPDDIS--------PQKVLHPD 3660
Query: 1121 AAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASA 1159
A VP PASP A + P P PT +ES+ A
Sbjct: 3661 MAKVP----PASPKTAKMMQRSMSDPKPLSPTADESSRA 3695
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 102 bits (253), Expect = 3e-21
Identities = 115/392 (29%), Positives = 151/392 (38%), Gaps = 68/392 (17%)
Query: 973 GPVTPATTVH--APEEPDTAAVRVST--PEEPASPAAAVP-TPEEPTSPAAAVPTPEEPT 1027
GP PA APE P R P+ P P+ P P P PAA + P E +
Sbjct: 74 GPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGS 133
Query: 1028 SPAAAVPPPEEPTSPAAAVPTPEEPTSPAA-------AVPTPEEPTSPAAAVPTPEEPTS 1080
+ + A P P A P P P PA A P P P P P +P
Sbjct: 134 AGSCA-PVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPG-PGPGKPAG 191
Query: 1081 PAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTP 1140
P AA + + +AA+ +PA ++ PAA +P P+ PA+P + TP
Sbjct: 192 PGAA-----QTLNGSAALLNSHHAAAPAVSLVNN----GPAALLPLPK-PAAPGTVIQTP 241
Query: 1141 E---EPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTS 1197
A PAPA P+P A P P A+PAAA P P + ATL P
Sbjct: 242 PFVGAAAPPAPAAPSPP-------AAPAP---AAPAAAPPPPPPAP------ATLARPPG 285
Query: 1198 PAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSS 1257
A PT A PA P + + A A P A V P ++
Sbjct: 286 HPAGPPTAA-----------PAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAA 334
Query: 1258 AAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPE 1317
AAA + SP V + A PAA PAS AA++ + ++P+P
Sbjct: 335 AAAPAPGVKAESPKRVV----QAAPPAAQTLAASGPASTAASMV---IGPTMQGALPSP- 386
Query: 1318 VPAIPAAAVPPMEEVSPIGVPFLGVSAHTDSV 1349
AAVPP +P G+P A T S+
Sbjct: 387 ------AAVPPPAPGTPTGLPKGAAGAVTQSL 412
Score = 100 bits (249), Expect = 1e-20
Identities = 138/545 (25%), Positives = 182/545 (33%), Gaps = 98/545 (17%)
Query: 832 QRPS----RTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVAS 887
QRP R VP A L P EG++ + P P AV A P P A
Sbjct: 103 QRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAG 162
Query: 888 IVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSA 947
+L A P P P G A ++ +AA+ +A
Sbjct: 163 PAALA---ARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNG--------SAALLNSHHAA 211
Query: 948 VAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAV 1007
S A +P+ + P P T + P P AAA
Sbjct: 212 APAVSLVNNGPAALLPLPK-------PAAPGTVIQTP---------------PFVGAAAP 249
Query: 1008 PTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTS 1067
P P P+ PAA P +PAAA PPP P +PA P P P A P P +
Sbjct: 250 PAPAAPSPPAAPA-----PAAPAAAPPPP--PPAPATLARPPGHPAGPPTAAPAVPPPAA 302
Query: 1068 -----PAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAA 1122
A A P P A V P + AAA + SP V + A PAA
Sbjct: 303 AQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVV----QAAPPAA 358
Query: 1123 AVPTPEEPASPAAAV---PT-----PEEPAFPAPAVPTPEESASAAVAVPTPEESASPAA 1174
PAS AA++ PT P A P PA TP A T S +P
Sbjct: 359 QTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTP-- 416
Query: 1175 AVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASL--- 1231
+A+ + + ATL PT A +P P ++ F P V E L
Sbjct: 417 -------TATTSGIRATL-TPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSENGQLLMI 468
Query: 1232 ---------AAAVSNPEEPTSPAAAVPTLEEP----------TSSAAAVLTPEELSSPAA 1272
A A + P+ +P A PT P T A +TP + +
Sbjct: 469 PQQALAQMQAQAHAQPQTTMAPRPATPTSAPPVQISTVQAPGTPIIARQVTPTTIIKQVS 528
Query: 1273 SVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPE--VP---AIPAAAVP 1327
T +P++ ++ A T + A TP+ VP +AA
Sbjct: 529 QAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGTATAVQTGTPQRTVPGATTTSSAATE 588
Query: 1328 PMEEV 1332
ME V
Sbjct: 589 TMENV 593
Score = 77.0 bits (188), Expect = 1e-13
Identities = 94/308 (30%), Positives = 113/308 (36%), Gaps = 56/308 (18%)
Query: 1074 TPEEPTSPAAAVPTPEEPTSPAAAV----PTPEEPTSPAAAVPTPEEPASPAAAVPTPEE 1129
TPE + A A+ SPA A P E AA P P A P P
Sbjct: 47 TPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPG 106
Query: 1130 PASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVV 1189
P SP P PA PAP AA P PE SA A VP AA V
Sbjct: 107 PPSPRR----PLVPAGPAPP---------AAKLRPPPEGSAGSCAPVPA-------AAAV 146
Query: 1190 ATLEEPTSPAASVPT-PAAMVATLEEFTSPA-----------ASVPTSEEPASLAAAVSN 1237
A EP + P PAA+ A P + P + + + +AA+ N
Sbjct: 147 AAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLN 206
Query: 1238 PEEPTSPA--------AAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSN 1289
+PA AA+ L +P + + TP + AA+ P P P+ PAA
Sbjct: 207 SHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVG--AAAPPAPAAPSPPAAPA-- 262
Query: 1290 LEEPASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPMEEVSPIGVPFLGVSAHTDSV 1349
PA+PAAA P P A PA P PA P A P V P G SA
Sbjct: 263 ---PAAPAAAPPPPPPA--PATLARPPGHPAGPPTAAP---AVPPPAAAQNGGSAGAAPA 314
Query: 1350 PISEEGTP 1357
P G P
Sbjct: 315 PAPAAGGP 322
Score = 74.7 bits (182), Expect = 6e-13
Identities = 99/341 (29%), Positives = 122/341 (35%), Gaps = 74/341 (21%)
Query: 996 TPEEPASPAAAVPTPEEPTSPAAAV----PTPEEPTSPAAAVPPPEEPTSPAAAVPTPEE 1051
TPE A+ A A+ SPA A P E AA PPP P P
Sbjct: 47 TPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPG 106
Query: 1052 PTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAV 1111
P P+P P PA P PAA + P E ++ + A P AAAV
Sbjct: 107 P-------PSPRRPLVPAGPAP-------PAAKLRPPPEGSAGSCA------PVPAAAAV 146
Query: 1112 PTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESAS 1171
EPA PA P +PA PAA P P P P P P + A
Sbjct: 147 AAGPEPA-PAG----PAKPAGPAALAARAGPGPGPGPG-PGPG---------PGPGKPAG 191
Query: 1172 PAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASL 1231
P AA ++ + +A + +PA S+ PAA +P + PA+
Sbjct: 192 PGAA-----QTLNGSAALLNSHHAAAPAVSLVN-----------NGPAALLPLPK-PAAP 234
Query: 1232 AAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPT---PEEPASPAAAVS 1288
+ P P AAA P P+ AA PA + P P P +PA
Sbjct: 235 GTVIQTP--PFVGAAAPPAPAAPSPPAA----------PAPAAPAAAPPPPPPAPATLAR 282
Query: 1289 NLEEPASPAAAVPT--PEVAAIPAASVPTPEVPAIPAAAVP 1327
PA P A P P AA S PA PAA P
Sbjct: 283 PPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPA-PAAGGP 322
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 100 bits (249), Expect = 1e-20
Identities = 137/564 (24%), Positives = 201/564 (35%), Gaps = 66/564 (11%)
Query: 829 PVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAAL----VPFPHEDIL 884
P +Q P + +A+P A +P G + A P + L V PH
Sbjct: 478 PAVQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAH 537
Query: 885 VASIVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEG 944
A I+S +AP + PA+ +P AA ++ + + APA AA T
Sbjct: 538 SAHILS-----------AAPIQVGQPAL-FQMPVSLAA-GSLPTQSQPAPAGPAATT--- 581
Query: 945 MSAVAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPA 1004
+ G + +A+A+ TP+G V PAT A E A V P A PA
Sbjct: 582 --VLQGVTLPPSAVAML-------NTPDGLVQPATPAAATGE--AAPVLTVQPAPQAPPA 630
Query: 1005 AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPT--SPAAAVPT- 1061
+ P P P A P P+ PT AAA P P +PE+ P +A PT
Sbjct: 631 VSTPLPLGLQQPQAQQP-PQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTA 689
Query: 1062 -----------PEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPT-------PEE 1103
P+E + + P + V P PA A P P+
Sbjct: 690 ILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQA 749
Query: 1104 PTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAP---AVPTPEESASAA 1160
P S A+ P P+ PA+ P P S P + P P+P P+ S +
Sbjct: 750 PDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQS 809
Query: 1161 VAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAA----MVATLEEFT 1216
V+ P E P P + L P P AS P P A +
Sbjct: 810 VSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVP--PPASNPAPTAPGPPQPPLRPQSQ 867
Query: 1217 SPAASVPTSEE--PASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASV 1274
P +P + P+S ++AV++ E TS PT + P + +P ++
Sbjct: 868 PPEGPLPPAPHLPPSSTSSAVASSSE-TSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTL 926
Query: 1275 PTPEEPASPAAAVSN-LEEPASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPMEEVS 1333
EPA+P + +P A+P P+ VP+ + A P + S
Sbjct: 927 HLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTS 986
Query: 1334 PIGVPFLGVSAHTDSVPISEEGTP 1357
P +A + GTP
Sbjct: 987 TSLGPLTSPAASVLVSGQAPSGTP 1010
Score = 97.8 bits (242), Expect = 6e-20
Identities = 120/477 (25%), Positives = 178/477 (37%), Gaps = 36/477 (7%)
Query: 858 TSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVP 917
+++A + P+G A E A +++++ AVS P + P
Sbjct: 591 SAVAMLNTPDGLVQPATPAAATGE---AAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQP 647
Query: 918 EGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTP 977
A + P+ T P + + V G P AI + + P+
Sbjct: 648 PQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQ 707
Query: 978 ATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPE 1037
+ P A+V VS P P A P P P + A + P+ P S A+ P P+
Sbjct: 708 PLSAEGPHLSVPASVIVSAP-----PPAQDPAPATPVAKGAGL-GPQAPDSQASPAPAPQ 761
Query: 1038 EPTSPAAAVPTPEEPTSPAAAVPTPEEP--TSPAAAVPTPEEPTSPAAAVPTPEEPTSPA 1095
P + P P S P + P SP P P+ P + P EP P
Sbjct: 762 IPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEP--PL 819
Query: 1096 AAVPTPE-EPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAV-PTPEEPAFPAPAVP-T 1152
P P+ PT P V + P A+ P P P P + P + P P P P
Sbjct: 820 HPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHL 879
Query: 1153 PEESASAAVAVPTPEESASPAAAVPTPAE-SASFAAVVATLEEPTSPAA--SVPTPAA-- 1207
P S S+AVA + S PA PTP++ F + PT P VP PAA
Sbjct: 880 PPSSTSSAVASSSETSSRLPA---PTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPP 936
Query: 1208 --MVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPE 1265
T + T+P ++P + V + + A P + ++S
Sbjct: 937 PPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLG------ 990
Query: 1266 ELSSPAASV-PTPEEPASPAAAVSNLEEPASPAAAVPTPEVAA---IPAASVPTPEV 1318
L+SPAASV + + P+ A S+ PA AA P + A A+++PT V
Sbjct: 991 PLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNV 1047
Score = 83.6 bits (205), Expect = 1e-15
Identities = 148/589 (25%), Positives = 216/589 (36%), Gaps = 94/589 (15%)
Query: 813 QVTKAGNTEPVLEEWIPVLQRPS-RTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAV 871
Q AG P L + P P+ T + AL +P+ T +AA A G V
Sbjct: 352 QPKPAGVLPPKLYQLTPKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKA--GQNV 409
Query: 872 VAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSV-PEGTAAVAAVSS-- 928
V + P P L A++ T AA P A ++V + +G++ V
Sbjct: 410 VLSGFPAP---ALQANVFKQPPATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHML 466
Query: 929 PEET------APAV------AAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVT 976
P + APAV +A G +A +P I PI GP++
Sbjct: 467 PGQNQFLLPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLA-GPLS 525
Query: 977 PATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAA-AVPTPEEPTSPAAAVPP 1035
+ +A + + P + PA + P S AA ++PT +P
Sbjct: 526 LGPVLAPHSGAHSAHILSAAPIQVGQPALF----QMPVSLAAGSLPTQSQPA-------- 573
Query: 1036 PEEPTSPAAAVPTPEE--PTSPAAAVPTPE---EPTSPAAAV----------PTPEEPTS 1080
P PAA P S A + TP+ +P +PAAA P P+ P
Sbjct: 574 ---PAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAP-- 628
Query: 1081 PAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVP--TPEEPASPAAAVPTPEEPASPAAAVP 1138
PA + P P P A P P+ PT AAA P T +P+ A+ P P +A P
Sbjct: 629 PAVSTPLPLGLQQPQAQQP-PQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATP 687
Query: 1139 T------------PEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFA 1186
T P+E + + P S A+V V P + PA A P A+ A
Sbjct: 688 TAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPV-AKGAGLG 746
Query: 1187 AVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPE-EPTSPA 1245
+ P S A+ P P A + P++S P+ A L + P PT P
Sbjct: 747 P-----QAPDSQASPAPAPQIPAAAPLKGPGPSSS-PSLPHQAPLGDSPHLPSPHPTRPP 800
Query: 1246 AAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEV 1305
+ P+ P+ +S P + P P P A L + P
Sbjct: 801 SRPPS------------RPQSVSRPPSEPPL--HPCPPPQAPPTLPGIFVIQNQLGVPPP 846
Query: 1306 AAIPAASVPTPEVPAIPAAAVPPMEEVSPIGVPFLGVSAHTDSVPISEE 1354
A+ PA + P P P + + PP + P P L S+ + +V S E
Sbjct: 847 ASNPAPTAPGPPQPPLRPQSQPPEGPLPP--APHLPPSSTSSAVASSSE 893
Score = 71.6 bits (174), Expect = 5e-12
Identities = 82/343 (23%), Positives = 123/343 (35%), Gaps = 43/343 (12%)
Query: 1056 AAAVPTPEEPTSPAAAVPTPEE----PTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAV 1111
A ++PT +P A T + P S A + TP+ PA TP T AA V
Sbjct: 563 AGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPA----TPAAATGEAAPV 618
Query: 1112 PT--PEEPASPAAAVPTP----EEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPT 1165
T P A PA + P P + A PTP+ A P P P +++ P
Sbjct: 619 LTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASS---PE 675
Query: 1166 PEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTS 1225
P +A PT + + E P ++ ++ A++ P A P
Sbjct: 676 KIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAP 735
Query: 1226 EEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSP----------AASVP 1275
P + A + P+ P S A+ P + P +AA + P SSP + +P
Sbjct: 736 ATPVAKGAGL-GPQAPDSQASPAPAPQIP--AAAPLKGPGPSSSPSLPHQAPLGDSPHLP 792
Query: 1276 TP---EEPASPAAAVSNLEEPASPAAAVPTPEVAAIPA----------ASVPTPEVPAIP 1322
+P P+ P + ++ P S P P A P VP P P
Sbjct: 793 SPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAP 852
Query: 1323 AAAVPPMEEVSPIGVPFLGVSAHTDSVPISEEGTPVLEEASST 1365
A PP + P P G +P S + V + ++
Sbjct: 853 TAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETS 895
Score = 68.9 bits (167), Expect = 3e-11
Identities = 103/430 (23%), Positives = 158/430 (36%), Gaps = 52/430 (12%)
Query: 826 EWIPVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAV-PAPEGTAVVAALVPFPHEDIL 884
E I + Q PS T +D+L LP ++A P A V P P +D
Sbjct: 675 EKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPA 734
Query: 885 VASIVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEG 944
A+ V+ AP+ PA +P A A + P P+ + ++ +
Sbjct: 735 PATPVAKG----AGLGPQAPDSQASPAPAPQIP----AAAPLKGP---GPSSSPSLPHQ- 782
Query: 945 MSAVAGFSPEWAALAITVPITEEDGTP--------EGPVTPATTVHAPEEPDTAAV---R 993
A G SP + T P + P E P+ P AP V +
Sbjct: 783 --APLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQ 840
Query: 994 VSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPT 1053
+ P ++PA P P +P + P PE P PA +PP +S ++AV + E T
Sbjct: 841 LGVPPPASNPAPTAPGPPQPPLRPQSQP-PEGPLPPAPHLPP----SSTSSAVASSSE-T 894
Query: 1054 SPAAAVPTPEE------PTSPAAAVPTPEEPTS---PAAAVPTPEEP------TSPAAAV 1098
S PTP + P+ PTP PT P A P P P T+P A+
Sbjct: 895 SSRLPAPTPSDFQLQFPPSQGPHKSPTPP-PTLHLVPEPAAPPPPPPRTFQMVTTPFPAL 953
Query: 1099 PTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESAS 1158
P P+ VP+ + A P + ++ + +P + P+ +A
Sbjct: 954 PQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAP 1013
Query: 1159 AAVAVPTPEESASPAAAVPTPAESASFAAVVATLE--EPTSPAASVPTPAAMVATLEEFT 1216
+ P P A+ PAE+ +FA+ + TL + S P+ + L
Sbjct: 1014 SHAPAPAP--MAATGLPPLLPAENKAFASNLPTLNVAKAASSGPGKPSGLQYESKLSGLK 1071
Query: 1217 SPAASVPTSE 1226
P P+ E
Sbjct: 1072 KPPTLQPSKE 1081
Score = 48.9 bits (115), Expect = 3e-05
Identities = 113/493 (22%), Positives = 164/493 (33%), Gaps = 62/493 (12%)
Query: 898 AAAVSAPERATVPAVT----VSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSP 953
AAAV+A +A P T + P A+ P++ + + +S P
Sbjct: 149 AAAVAAGPQALFPGSTDLLGLQGPPTVLTHQALVPPQD--------VVNKALSVQPFLQP 200
Query: 954 EWAALAITVPITEEDGTPEGPVTPATTVHAPEEP-DTAAVRVSTPEEPASPAAAVPTPEE 1012
PI G P G AT P V P S A P
Sbjct: 201 VGLGNVTLQPIPGLQGLPNGSPGGATAATLGLAPIQVVGQPVMALNTPTSQLLAKQVPVS 260
Query: 1013 PTSPAAAVPTPEEPTSPAAAVPPPEEP-----TSPAAAVPTPEEPTSPAAAVPTPEEPTS 1067
+AA P+ EP + A+A P+ + +AAV T S PT
Sbjct: 261 GYLASAAGPS--EPVTLASAGVSPQGAGLVIQKNLSAAVATTLNGNSVFGGAGAASAPTG 318
Query: 1068 PAAAVPTPEEP---TSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAV 1124
+ P P +SP P +P P P P TP +P +PA A
Sbjct: 319 TPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTP-KPFAPAGAT 377
Query: 1125 PTPE-EPASPAAAVPTPEEPAFPA----------PAVPTPEESASAAVAVPTPEESASPA 1173
T + EP + P+ F A P P A+ P A+P
Sbjct: 378 LTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAAP- 436
Query: 1174 AAVPTPAESASFAAVVATLEEPTSPAASVPTPAA-MVATLEEFTSPAASVPTSEEPASLA 1232
P P + S V L + +S+ PA M+ +F P A P + P L+
Sbjct: 437 ---PQPPGALSKPMSVHLLNQ----GSSIVIPAQHMLPGQNQFLLPGA--PAVQLPQQLS 487
Query: 1233 AAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVP--TPEEPASPAAAVSNL 1290
A +N AAA T + A +LT + L+ P + P P A A +S
Sbjct: 488 ALPANVGGQILAAAAPHTGGQ--LIANPILTNQNLAGPLSLGPVLAPHSGAHSAHILSAA 545
Query: 1291 EEPASPAAAVPTP---EVAAIPAASVPTPEVPA---------IPAAAVPPMEEVSPIGVP 1338
A P ++P S P P PA +P +AV + + P
Sbjct: 546 PIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQP 605
Query: 1339 FLGVSAHTDSVPI 1351
+A ++ P+
Sbjct: 606 ATPAAATGEAAPV 618
Score = 38.9 bits (89), Expect = 0.036
Identities = 83/370 (22%), Positives = 127/370 (34%), Gaps = 60/370 (16%)
Query: 997 PEEPASPAAAVPTPEEPTSPAAAVPT--PEEPTSPAAAV-PPPEEPT-----------SP 1042
P+E S + ++ P +S +P P ++P A+ PPP PT SP
Sbjct: 1198 PDEYVSSSRSLGLPIAASSEGHRLPGHGPLSSSAPGASTQPPPHLPTKLVIRHGGAGGSP 1257
Query: 1043 A-------AAVPTPEEPTSPAAAVPTPEEPTSPAAAVP---TPEEPTSPAAAVPTPEEP- 1091
+ +++ + +S A+++ E+ P+ P T E + + +E
Sbjct: 1258 SVTWARASSSLSSSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAG 1317
Query: 1092 ---------TSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEE 1142
P P P A P P P P + + PAA P
Sbjct: 1318 LSKVVHNTALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLG 1377
Query: 1143 PAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESA---SFAAVVATLEEPTSPA 1199
A P +P + E P A TPA A S A + A ++E TS
Sbjct: 1378 TAPHCPRLPLRKTYR---------ENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGL 1428
Query: 1200 ASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNP--EEPTSPAAAVPTLEEPTSS 1257
+ A +E P E AS A +P E P P A E P
Sbjct: 1429 I-----RELAAVEDELYQRMLKGPPPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVD 1483
Query: 1258 AAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEP--ASPAAAVPTPEVAAIPAASVPT 1315
A+ + SP T E S ++ NL++ +PA + P A PA+ P
Sbjct: 1484 QASFSS----DSPQDDTLT-EHLQSAIDSILNLQQAPGRTPAPSYPHAASAGTPASPPPL 1538
Query: 1316 PEVPAIPAAA 1325
A P ++
Sbjct: 1539 HRPEAYPPSS 1548
>gi|112421108 capicua homolog [Homo sapiens]
Length = 1608
Score = 99.4 bits (246), Expect = 2e-20
Identities = 139/555 (25%), Positives = 205/555 (36%), Gaps = 98/555 (17%)
Query: 806 LNIFPEKQVTKAGNTEPVLEEWIPVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPA 865
L I + KAG V + +P L + + A P AA PS T+
Sbjct: 808 LGILQPGALGKAGGITQV-QYILPTLPQQLQVAPAPAPAPGTKAAAPSGPAPTTSIRFTL 866
Query: 866 PEGTA----VVAALVPFPHEDILVA----------SIVSLEEEDVTAAAVSAPERATVP- 910
P GT+ V+AA P P IL + S+ ++ +A P + VP
Sbjct: 867 PPGTSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSVSPVQAPPPGGSAQLLPGKVLVPL 926
Query: 911 -AVTVSVPEGTAA--VAAVSSPEETA-------PAVAAAITQEGMSAVAGFSPEWAALAI 960
A ++SV G A + VS P P+ +T +S +G P + +
Sbjct: 927 AAPSMSVRGGGAGQPLPLVSPPFSVPVQNGAQPPSKIIQLTPVPVSTPSGLVPPLSPATL 986
Query: 961 TVPITEEDGTPEGPVTPATT-VHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAA 1019
P ++ P+ + P++T + + A+ + T PAS A T PTS A
Sbjct: 987 PGPTSQ----PQKVLLPSSTRITYVQSAGGHALPLGT--SPASSQAGTVTSYGPTSSVAL 1040
Query: 1020 VPTPEEPTSPAAAVPPPEEPTSPAAA--------VPTPEEPTS----------------- 1054
T P+ PA P +P A VP+P+ P +
Sbjct: 1041 GFTSLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSPQLPPACAAPGGPVITAFYSGSP 1100
Query: 1055 -PAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPT 1113
P ++ P + +P + V T T+P AA P+ P +PA A P P P A A
Sbjct: 1101 APTSSAPLAQPSQAPPSLVYTVATSTTPPAATILPKGPPAPATATPAPTSPFPSATAGSM 1160
Query: 1114 PEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPA 1173
+P A P+P+ P AA+ + +F A A P P P + P
Sbjct: 1161 TYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFEAGASGRPG---------PAPRQPLEP- 1210
Query: 1174 AAVPTPAESASFAAVVATLEEPTSPAASV---PTPAAMVATLEEFTSPAASVPTSEEPAS 1230
+ EPT+P + + PTP A E +T A S P PA
Sbjct: 1211 ----------------GPVREPTAPESELEGQPTPPAPPPLPETWTPTARSSPPLPPPAE 1254
Query: 1231 LAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPA-SPAAAVSN 1289
+ PE + A+ P SS++ P + PTP PA +PA A
Sbjct: 1255 ERTSAKGPE---TMASKFP------SSSSDWRVPGQGLENRGEPPTPPSPAPAPAVAPGG 1305
Query: 1290 LEEPASPAAAVPTPE 1304
E +S AA TPE
Sbjct: 1306 SSESSSGRAAGDTPE 1320
Score = 86.7 bits (213), Expect = 1e-16
Identities = 151/587 (25%), Positives = 205/587 (34%), Gaps = 99/587 (16%)
Query: 822 PVLEEWIPVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVP--APEGTAVV------- 872
PV +P+ +P T+ D A E GT + VP +P G ++V
Sbjct: 678 PVSSTPVPIASKPFPTSGRAEASPN-DTAGARTEMGTG-SRVPGGSPLGVSLVYSDKKSA 735
Query: 873 AALVPFPHEDILVAS----IVSLEEEDVTAAAVS-----APERATVPAVTVSVPEG--TA 921
AA P PH LVA V VT V AP V + P G TA
Sbjct: 736 AATSPAPH---LVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQGAPGGGTTA 792
Query: 922 AVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTPATTV 981
A + P V I Q G AG + + T+P + P P T
Sbjct: 793 GSGAGAGSGPNGP-VPLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPAPA-PGTKA 850
Query: 982 HAPEEP-DTAAVRVSTPEEPASP----AAAVPTPEEPT--SPAAAVPTPEEPTSPAAAVP 1034
AP P T ++R + P ++ AA PTP P S +A P + SP A P
Sbjct: 851 AAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSVSPVQAPP 910
Query: 1035 P-------PEEPTSPAAA---------VPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEP 1078
P P + P AA P SP +VP P+ + P
Sbjct: 911 PGGSAQLLPGKVLVPLAAPSMSVRGGGAGQPLPLVSPPFSVPVQNGAQPPSKIIQLTPVP 970
Query: 1079 TSPAAAVPTPEEPTSPAAAVPTPEEPTSPAA------------AVPTPEEPASPAAAVPT 1126
S + + P P + P++ P++ A+P PAS A T
Sbjct: 971 VSTPSGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGTSPASSQAGTVT 1030
Query: 1127 PEEPASPAAAVPT---PEEPAFPAPAVPTPEESASAAVAV---PTPEESASPAAAVPT-P 1179
P S A T P PAF P + + A V P P PA A P P
Sbjct: 1031 SYGPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSPQLPPACAAPGGP 1090
Query: 1180 AESASFAAVVATLEEPTSPAASVP---TPAAMVATLEEFTSPAASVPTSEEPASLAAAVS 1236
+A ++ A PTS A P ++V T+ T+P A+ + P + A A
Sbjct: 1091 VITAFYSGSPA----PTSSAPLAQPSQAPPSLVYTVATSTTPPAATILPKGPPAPATATP 1146
Query: 1237 NPEEPTSPAAA---VPTLEEPTSSAAAVLTPEELSSPAASVPT----------------- 1276
P P A A +L P + + P+++ + AS+P
Sbjct: 1147 APTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFEAGASGRPGPAPRQ 1206
Query: 1277 PEEPA---SPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPA 1320
P EP P A S LE +P A P PE A S P PA
Sbjct: 1207 PLEPGPVREPTAPESELEGQPTPPAPPPLPETWTPTARSSPPLPPPA 1253
Score = 66.2 bits (160), Expect = 2e-10
Identities = 143/619 (23%), Positives = 207/619 (33%), Gaps = 92/619 (14%)
Query: 771 RLNPDGVETVNDTKPELNVASSEGGEMERRDSDSFLNIFPEKQVTKAGNTE------PVL 824
R P+ V + P + A GG + L + P K+ + G P L
Sbjct: 600 RKRPESVGGLEPPGPSVIAAPPSGGGNILQT----LVLPPNKEEQEGGGARVPSAPAPSL 655
Query: 825 EEWIPV--LQRPSRTAAVPTVKDALDAALP--SPEEGTSIAAVPAPEGTAVVAALVP--- 877
P L RP+ T V+ +P S TS A +P TA +
Sbjct: 656 AYGAPAAPLSRPAATMVTNVVRPVSSTPVPIASKPFPTSGRAEASPNDTAGARTEMGTGS 715
Query: 878 -FPHEDILVASIVSLEEEDVTAAA-----VSAPERATV---PAVTVSVPEGTAAVAAVSS 928
P L S+V +++ A + V+ P TV PA ++ GT A +
Sbjct: 716 RVPGGSPLGVSLVYSDKKSAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAP 775
Query: 929 P--EETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEE 986
P + A T G A AG P P G + P A
Sbjct: 776 PAVQFIAQGAPGGGTTAGSGAGAGSGPNGPV-------------PLGILQPGALGKAGGI 822
Query: 987 PDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSP---A 1043
+ + P++ A P P AA P+ PT+ PP T+ A
Sbjct: 823 TQVQYILPTLPQQLQVAPAPAPAP----GTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLA 878
Query: 1044 AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE 1103
A PTP P + P P A +V + P +A P + P AA
Sbjct: 879 ATAPTPGIPILQSV----PSAPPPKAQSVSPVQAPPPGGSAQLLPGKVLVPLAAPSMSVR 934
Query: 1104 PTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVP-TPEEPAFPAPAVPTPEESASAAVA 1162
+P SP +VP P+ + TP + P+ VP P A+
Sbjct: 935 GGGAGQPLPL----VSPPFSVPVQNGAQPPSKIIQLTPVPVSTPSGLVP-PLSPATLPGP 989
Query: 1163 VPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASV 1222
P++ P++ T +SA A L TSPA+S A
Sbjct: 990 TSQPQKVLLPSSTRITYVQSAGGHA----LPLGTSPASS-----------------QAGT 1028
Query: 1223 PTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEP-- 1280
TS P S A P+ PA P L ++ A +L P ++ + VP+P+ P
Sbjct: 1029 VTSYGPTSSVALGFTSLGPSGPAFVQPLL---SAGQAPLLAPGQVG--VSPVPSPQLPPA 1083
Query: 1281 -ASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPMEEVSPIG--V 1337
A+P V SPA PT + P V + + PP + P G
Sbjct: 1084 CAAPGGPVITAFYSGSPA---PTSSAPLAQPSQAPPSLVYTVATSTTPPAATILPKGPPA 1140
Query: 1338 PFLGVSAHTDSVPISEEGT 1356
P A T P + G+
Sbjct: 1141 PATATPAPTSPFPSATAGS 1159
Score = 65.9 bits (159), Expect = 3e-10
Identities = 120/517 (23%), Positives = 173/517 (33%), Gaps = 115/517 (22%)
Query: 915 SVPEGTAAVAAVS-SPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEG 973
+ P G A S SP T+ A A +Q S V + A T+ P+G
Sbjct: 1085 AAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATSTTPPAATI-------LPKG 1137
Query: 974 PVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAV------------- 1020
P PAT AP P +A S +P A P+P+ P AA+
Sbjct: 1138 PPAPATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFEAGAS 1197
Query: 1021 ----PTPEEPTSPAAAVPPPEEPTSPAAAV---PTPEEPTSPAAAVPTPEEPTSPAAAVP 1073
P P +P P P EPT+P + + PTP P P TP +SP P
Sbjct: 1198 GRPGPAPRQPLEPG----PVREPTAPESELEGQPTPPAPP-PLPETWTPTARSSPPLPPP 1252
Query: 1074 TPEEPTSPAAAVPTPEEPTS------PAAAVPTPEEPTSPAAAVPTP-------EEPASP 1120
E ++ + P+S P + EP +P + P P E +S
Sbjct: 1253 AEERTSAKGPETMASKFPSSSSDWRVPGQGLENRGEPPTPPSPAPAPAVAPGGSSESSSG 1312
Query: 1121 AAAVPTPE--EPASPAAAV---PTPEEPAF------------------------PAPAVP 1151
AA TPE E A V P P + F P +P
Sbjct: 1313 RAAGDTPERKEAAGTGKKVKVRPPPLKKTFDSVDNRVLSEVDFEERFAELPEFRPEEVLP 1372
Query: 1152 TP--EESASAAVAV---------------PTPEESASP---------AAAVPTPAESASF 1185
+P + A++ A+ PE+ SP ++ P +SA
Sbjct: 1373 SPTLQSLATSPRAILGSYRKKRKNSTDLDSAPEDPTSPKRKMRRRSSCSSEPNTPKSAKC 1432
Query: 1186 AAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVP-TSEEPASLAAAVSN-----PE 1239
+ T + + A V + LE P +S+ T ++ +L + P
Sbjct: 1433 EGDIFTFDRTGTEAEDV------LGELEYDKVPYSSLRRTLDQRRALVMQLFQDHGFFPS 1486
Query: 1240 EPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAA 1299
+ A + S L E+ TP E A A + P AAA
Sbjct: 1487 AQATAAFQARYADIFPSKVCLQLKIREVRQKIMQAATPTEQPPGAEAPLPVPPPTGTAAA 1546
Query: 1300 -VPTPEVAAIPAASVPTPEVPAIPAA-AVPPMEEVSP 1334
PTP A P + P+ + AA +PP E P
Sbjct: 1547 PAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESGP 1583
Score = 58.5 bits (140), Expect = 4e-08
Identities = 108/450 (24%), Positives = 153/450 (34%), Gaps = 69/450 (15%)
Query: 910 PAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDG 969
P V G+A ++ SSP A + A+A T + + + E + P+
Sbjct: 520 PPVAFGKGYGSAPSSSASSP---ASSSASAATSFSLGSGTFKAQESGQGSTAGPLRPPPP 576
Query: 970 TPEGPVTPA-TTVHAPEEPDTAAVRVSTPE-----EPASPAAAVPTPEEPTSPAAAV--- 1020
GP TP+ T P +P A R PE EP P+ P + +
Sbjct: 577 GAGGPATPSKATRFLPMDP--ATFRRKRPESVGGLEPPGPSVIAAPPSGGGNILQTLVLP 634
Query: 1021 PTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTS-PAAAVPTPEEPTSPAAAVPTPEEPT 1079
P EE A VP +P+ A P P S PAA + T P ++ P P
Sbjct: 635 PNKEEQEGGGARVP---SAPAPSLAYGAPAAPLSRPAATMVT--NVVRPVSSTPVP---- 685
Query: 1080 SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPT 1139
A+ P P + A+ T T P SP + S AA P
Sbjct: 686 --IASKPFPTSGRAEASPNDTAGARTEMGTGSRVPG--GSPLGVSLVYSDKKSAAATSPA 741
Query: 1140 PEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPA 1199
P A P + + V TP A AV A+ A A
Sbjct: 742 PHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQGAPGGGTTAGSGAGAGSG 801
Query: 1200 ASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAA 1259
+ P P ++ +P +L A T +PTL
Sbjct: 802 PNGPVPLGIL-----------------QPGALGKAGGI----TQVQYILPTL-------- 832
Query: 1260 AVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVP--TPEVAAIPAASVPTPE 1317
P++L A P P + AAA S S +P T + AA+ PTP
Sbjct: 833 ----PQQLQVAPAPAPAP---GTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPG 885
Query: 1318 VP---AIPAAAVPPMEEVSPIGVPFLGVSA 1344
+P ++P+A P + VSP+ P G SA
Sbjct: 886 IPILQSVPSAPPPKAQSVSPVQAPPPGGSA 915
Score = 53.1 bits (126), Expect = 2e-06
Identities = 131/589 (22%), Positives = 202/589 (34%), Gaps = 121/589 (20%)
Query: 834 PSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEE 893
PS A V + A A L +P + ++ VP+P+ AA P ++ A S
Sbjct: 1047 PSGPAFVQPLLSAGQAPLLAPGQ-VGVSPVPSPQLPPACAA----PGGPVITA-FYSGSP 1100
Query: 894 EDVTAAAVSAPERA------------TVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAIT 941
++A ++ P +A T PA T+ +P+G A A ++P T+P +A
Sbjct: 1101 APTSSAPLAQPSQAPPSLVYTVATSTTPPAATI-LPKGPPA-PATATPAPTSPFPSATAG 1158
Query: 942 QEGMSAVAGFS-------PEWAALAI-TVPITEEDGTPEGPVTPATTVHAPEEPDTAAVR 993
S VA + P+ AI ++P+ + G PA P EP
Sbjct: 1159 SMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFEAGASGRPGPAP--RQPLEPGP---- 1212
Query: 994 VSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPT 1053
V P P S PTP P P PE T A + PP P + PE
Sbjct: 1213 VREPTAPESELEGQPTPPAPP------PLPETWTPTARSSPPLPPPAEERTSAKGPETMA 1266
Query: 1054 S-----------PAAAVPTPEEPTSPAAAVPTP-------EEPTSPAAAVPTPEEPTSPA 1095
S P + EP +P + P P E +S AA TPE +
Sbjct: 1267 SKFPSSSSDWRVPGQGLENRGEPPTPPSPAPAPAVAPGGSSESSSGRAAGDTPERKEAAG 1326
Query: 1096 AAV-----PTPEEPT------------------------SPAAAVPTPEEPA---SPAAA 1123
P P + T P +P+P + SP A
Sbjct: 1327 TGKKVKVRPPPLKKTFDSVDNRVLSEVDFEERFAELPEFRPEEVLPSPTLQSLATSPRAI 1386
Query: 1124 VPTPEEPASPAAAVPT-PEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAES 1182
+ + + + + + PE+P P + S+ + P +SA + T +
Sbjct: 1387 LGSYRKKRKNSTDLDSAPEDPTSPKRKM----RRRSSCSSEPNTPKSAKCEGDIFTFDRT 1442
Query: 1183 ASFAA-VVATLEEPTSPAASVP-TPAAMVATLEEFTSPAASVPTSEEPASLAAAVSN--- 1237
+ A V+ LE P +S+ T A + + P+++ A+ A ++
Sbjct: 1443 GTEAEDVLGELEYDKVPYSSLRRTLDQRRALVMQLFQDHGFFPSAQATAAFQARYADIFP 1502
Query: 1238 ----------PEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAV 1287
AA PT E+P + A + P + AA PTP P
Sbjct: 1503 SKVCLQLKIREVRQKIMQAATPT-EQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGP---- 1557
Query: 1288 SNLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPMEEVSPIG 1336
+P SP++ T + A P P P P P P G
Sbjct: 1558 ----DPTSPSSDSGTAQAA--PPLPPPPESGPGQPGWEGAPQPSPPPPG 1600
Score = 43.5 bits (101), Expect = 0.001
Identities = 29/92 (31%), Positives = 37/92 (40%), Gaps = 7/92 (7%)
Query: 1032 AVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEP 1091
A P E+P A +P P + AA PTP P P+ + T+ AA P P P
Sbjct: 1521 AATPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAP-PLPPPP 1579
Query: 1092 TSPAAAVPTPEEPTSPAAAVPTPEEPASPAAA 1123
S P +P A P+P P AA
Sbjct: 1580 ES------GPGQPGWEGAPQPSPPPPGPSTAA 1605
Score = 42.7 bits (99), Expect = 0.002
Identities = 35/97 (36%), Positives = 41/97 (42%), Gaps = 16/97 (16%)
Query: 1044 AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPA----AAVP 1099
AA PT E+P P A P P P + AA P PT A P P P+S + AA P
Sbjct: 1521 AATPT-EQP--PGAEAPLPVPPPTGTAAAPA---PTPSPAGGPDPTSPSSDSGTAQAAPP 1574
Query: 1100 TPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAA 1136
P P S P +P A P+P P AA
Sbjct: 1575 LPPPPES------GPGQPGWEGAPQPSPPPPGPSTAA 1605
Score = 42.4 bits (98), Expect = 0.003
Identities = 32/91 (35%), Positives = 39/91 (42%), Gaps = 7/91 (7%)
Query: 1070 AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPA-AAVPTPE 1128
AA PT E+P P A P P P + AA P PT A P P P+S + A P
Sbjct: 1521 AATPT-EQP--PGAEAPLPVPPPTGTAAAPA---PTPSPAGGPDPTSPSSDSGTAQAAPP 1574
Query: 1129 EPASPAAAVPTPEEPAFPAPAVPTPEESASA 1159
P P + P P P+ P P S +A
Sbjct: 1575 LPPPPESGPGQPGWEGAPQPSPPPPGPSTAA 1605
Score = 42.0 bits (97), Expect = 0.004
Identities = 28/85 (32%), Positives = 38/85 (44%), Gaps = 10/85 (11%)
Query: 1109 AAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEE-SASAAVAVPTPE 1167
AA PT E+P A +P P + AA PTP P P P+ + +A AA +P P
Sbjct: 1521 AATPT-EQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPP 1579
Query: 1168 ES--------ASPAAAVPTPAESAS 1184
ES +P + P P S +
Sbjct: 1580 ESGPGQPGWEGAPQPSPPPPGPSTA 1604
Score = 41.6 bits (96), Expect = 0.006
Identities = 31/93 (33%), Positives = 39/93 (41%), Gaps = 8/93 (8%)
Query: 1018 AAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE 1077
AA PT E+P A +P P + AA PTP P P+ + T+ AA P P
Sbjct: 1521 AATPT-EQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAP-PLPPP 1578
Query: 1078 PTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAA 1110
P S P +P A P+P P AA
Sbjct: 1579 PES------GPGQPGWEGAPQPSPPPPGPSTAA 1605
Score = 40.8 bits (94), Expect = 0.009
Identities = 35/97 (36%), Positives = 41/97 (42%), Gaps = 16/97 (16%)
Query: 1005 AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPA----AAVP 1060
AA PT E+P P A P P P + AA P PT A P P P+S + AA P
Sbjct: 1521 AATPT-EQP--PGAEAPLPVPPPTGTAAAP---APTPSPAGGPDPTSPSSDSGTAQAAPP 1574
Query: 1061 TPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAA 1097
P P S P +P A P+P P AA
Sbjct: 1575 LPPPPES------GPGQPGWEGAPQPSPPPPGPSTAA 1605
Score = 40.0 bits (92), Expect = 0.016
Identities = 35/102 (34%), Positives = 45/102 (44%), Gaps = 16/102 (15%)
Query: 1083 AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEE 1142
AA PT E+P P A P P P + AA P P SPA P P P+S +
Sbjct: 1521 AATPT-EQP--PGAEAPLPVPPPTGTAAAPAP--TPSPAGG-PDPTSPSSDSGT------ 1568
Query: 1143 PAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESAS 1184
A AP +P P ES P E + P+ P P+ +A+
Sbjct: 1569 -AQAAPPLPPPPESGPGQ---PGWEGAPQPSPPPPGPSTAAT 1606
Score = 39.7 bits (91), Expect = 0.021
Identities = 32/97 (32%), Positives = 40/97 (41%), Gaps = 14/97 (14%)
Query: 992 VRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPA----AAVP 1047
++ +TP E P A P P P + AA P PT A P P P+S + AA P
Sbjct: 1519 MQAATPTEQP-PGAEAPLPVPPPTGTAAAPA---PTPSPAGGPDPTSPSSDSGTAQAAPP 1574
Query: 1048 TPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAA 1084
P P S P +P A P+P P AA
Sbjct: 1575 LPPPPES------GPGQPGWEGAPQPSPPPPGPSTAA 1605
Score = 38.5 bits (88), Expect = 0.047
Identities = 38/145 (26%), Positives = 57/145 (39%), Gaps = 12/145 (8%)
Query: 983 APEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEP--T 1040
AP +PD + V+ S ++PAS A +EP AA E P + P P T
Sbjct: 45 APSQPDPS-VQPSEAQQPASHPVASNQSKEPAESAAV--AHERPPGGTGSADPERPPGAT 101
Query: 1041 SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEP----TSPAA 1096
P + P P P + P T A+ P P EP + ++ SP
Sbjct: 102 CPESPGPGPPHPLGVVESGKGPPPTTEEEASGP-PGEPRLDSETESDHDDAFLSIMSPEI 160
Query: 1097 AVPTP--EEPTSPAAAVPTPEEPAS 1119
+P P + T +A+P + +S
Sbjct: 161 QLPLPPGKRRTQSLSALPKERDSSS 185
Score = 37.0 bits (84), Expect = 0.14
Identities = 26/88 (29%), Positives = 35/88 (39%), Gaps = 9/88 (10%)
Query: 985 EEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAA-AVPPPEEPTSPA 1043
E+P A + P + AA PTP P P+ + T+ AA +PPP E
Sbjct: 1526 EQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPE----- 1580
Query: 1044 AAVPTPEEPTSPAAAVPTPEEPTSPAAA 1071
P +P A P+P P AA
Sbjct: 1581 ---SGPGQPGWEGAPQPSPPPPGPSTAA 1605
Score = 35.8 bits (81), Expect = 0.30
Identities = 44/183 (24%), Positives = 60/183 (32%), Gaps = 7/183 (3%)
Query: 1140 PEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPA 1199
PE P P P V + SA + + S+S +AA S +F A + P
Sbjct: 512 PEPPGPPDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSGTFKAQESGQGSTAGPL 571
Query: 1200 ASVPTPAAMVATLEEFTSPAASVPTS---EEPASLAAAVSNPEEPTSPAAAVPTLEEPTS 1256
P A AT + T P + + P S V E P A P
Sbjct: 572 RPPPPGAGGPATPSKATRFLPMDPATFRRKRPES----VGGLEPPGPSVIAAPPSGGGNI 627
Query: 1257 SAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTP 1316
VL P + P PA A + + PAA + T V + + VP
Sbjct: 628 LQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSRPAATMVTNVVRPVSSTPVPIA 687
Query: 1317 EVP 1319
P
Sbjct: 688 SKP 690
Score = 35.0 bits (79), Expect = 0.52
Identities = 53/188 (28%), Positives = 69/188 (36%), Gaps = 22/188 (11%)
Query: 997 PEEPASPAAA------VPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPE 1050
P PAS AA+ V T EP S A P P A P+ P+ A +
Sbjct: 7 PLMPASSAASRGLGMFVWTNVEPRSVAVF---PWHSLVPFLAPSQPDPSVQPSEA----Q 59
Query: 1051 EPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPT-PEEPTSPAAAVPTPEEP----T 1105
+P S A +EP +AAV P +A P P T P + P P P
Sbjct: 60 QPASHPVASNQSKEPAE-SAAVAHERPPGGTGSADPERPPGATCPESPGPGPPHPLGVVE 118
Query: 1106 SPAAAVPTPEEPASPAAAVP--TPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAV 1163
S PT EE AS P E + A + P P P + S + A+
Sbjct: 119 SGKGPPPTTEEEASGPPGEPRLDSETESDHDDAFLSIMSPEIQLPLPPGKRRTQSLS-AL 177
Query: 1164 PTPEESAS 1171
P +S+S
Sbjct: 178 PKERDSSS 185
Score = 31.2 bits (69), Expect = 7.5
Identities = 53/193 (27%), Positives = 68/193 (35%), Gaps = 26/193 (13%)
Query: 1049 PEEPTSPAAA------VPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPE 1102
P P S AA+ V T EP S A P P A P+ P+ A +
Sbjct: 7 PLMPASSAASRGLGMFVWTNVEPRSVAVF---PWHSLVPFLAPSQPDPSVQPSEA----Q 59
Query: 1103 EPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEE----PAFPAPAVPTP-EESA 1157
+P S A +EPA +AAV P +A P P P P P P
Sbjct: 60 QPASHPVASNQSKEPAE-SAAVAHERPPGGTGSADPERPPGATCPESPGPGPPHPLGVVE 118
Query: 1158 SAAVAVPTPEESASPAAAVP---TPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEE 1214
S PT EE AS P + ES A ++ + SP +P P T
Sbjct: 119 SGKGPPPTTEEEASGPPGEPRLDSETESDHDDAFLSIM----SPEIQLPLPPGKRRTQSL 174
Query: 1215 FTSPAASVPTSEE 1227
P +SE+
Sbjct: 175 SALPKERDSSSEK 187
Score = 31.2 bits (69), Expect = 7.5
Identities = 25/87 (28%), Positives = 31/87 (35%), Gaps = 7/87 (8%)
Query: 972 EGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAA 1031
E P + P TAA TP P P+ + T+ AA P P P S
Sbjct: 1526 EQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAP-PLPPPPES--- 1581
Query: 1032 AVPPPEEPTSPAAAVPTPEEPTSPAAA 1058
P +P A P+P P AA
Sbjct: 1582 ---GPGQPGWEGAPQPSPPPPGPSTAA 1605
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.124 0.352
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 66,550,064
Number of Sequences: 37866
Number of extensions: 4307002
Number of successful extensions: 117795
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 699
Number of HSP's successfully gapped in prelim test: 2067
Number of HSP's that attempted gapping in prelim test: 26060
Number of HSP's gapped (non-prelim): 26632
length of query: 1427
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1312
effective length of database: 13,892,928
effective search space: 18227521536
effective search space used: 18227521536
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.