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Search of human proteins with 149363656
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|149363656 SEC15-like 2 [Homo sapiens]
(811 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|149363656 SEC15-like 2 [Homo sapiens] 1619 0.0
gi|65507403 SEC15-like 1 isoform a [Homo sapiens] 1165 0.0
gi|62243652 SEC15-like 1 isoform b [Homo sapiens] 1129 0.0
gi|31982906 cingulin-like 1 [Homo sapiens] 44 8e-04
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 42 0.002
gi|96975038 coiled-coil domain containing 100 [Homo sapiens] 42 0.003
gi|63252904 tropomyosin 1 alpha chain isoform 6 [Homo sapiens] 41 0.004
gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens] 41 0.004
gi|71061468 centromere protein E [Homo sapiens] 41 0.005
gi|148664246 harmonin-interacting ankyrin-repeat containing prot... 40 0.009
gi|169214072 PREDICTED: zinc finger and SCAN domain containing 5... 39 0.019
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 39 0.025
gi|7656888 angiopoietin-like 3 precursor [Homo sapiens] 38 0.033
gi|109255234 centrosomal protein 290kDa [Homo sapiens] 38 0.033
gi|4885583 Rho-associated, coiled-coil containing protein kinase... 38 0.043
gi|56961680 coiled-coil domain containing 147 [Homo sapiens] 38 0.043
gi|156104908 myosin heavy chain 6 [Homo sapiens] 37 0.056
gi|169214427 PREDICTED: zinc finger and SCAN domain containing 5... 37 0.096
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens] 36 0.16
gi|19924131 RAD50 homolog isoform 2 [Homo sapiens] 36 0.16
gi|19924129 RAD50 homolog isoform 1 [Homo sapiens] 36 0.16
gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens] 36 0.16
gi|148727333 adenylate kinase 7 [Homo sapiens] 36 0.16
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 35 0.21
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 35 0.21
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 35 0.21
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 35 0.21
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 35 0.21
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 35 0.28
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 35 0.28
>gi|149363656 SEC15-like 2 [Homo sapiens]
Length = 811
Score = 1619 bits (4193), Expect = 0.0
Identities = 811/811 (100%), Positives = 811/811 (100%)
Query: 1 MERGKMAEAESLETAAEHERILREIESTDTACIGPTLRSVYDGEEHGRFMEKLETRIRNH 60
MERGKMAEAESLETAAEHERILREIESTDTACIGPTLRSVYDGEEHGRFMEKLETRIRNH
Sbjct: 1 MERGKMAEAESLETAAEHERILREIESTDTACIGPTLRSVYDGEEHGRFMEKLETRIRNH 60
Query: 61 DREIEKMCNFHYQGFVDSITELLKVRGEAQKLKNQVTDTNRKLQHEGKELVIAMEELKQC 120
DREIEKMCNFHYQGFVDSITELLKVRGEAQKLKNQVTDTNRKLQHEGKELVIAMEELKQC
Sbjct: 61 DREIEKMCNFHYQGFVDSITELLKVRGEAQKLKNQVTDTNRKLQHEGKELVIAMEELKQC 120
Query: 121 RLQQRNISATVDKLMLCLPVLEMYSKLRDQMKTKRHYPALKTLEHLEHTYLPQVSHYRFC 180
RLQQRNISATVDKLMLCLPVLEMYSKLRDQMKTKRHYPALKTLEHLEHTYLPQVSHYRFC
Sbjct: 121 RLQQRNISATVDKLMLCLPVLEMYSKLRDQMKTKRHYPALKTLEHLEHTYLPQVSHYRFC 180
Query: 181 KVMVDNIPKLREEIKDVSMSDLKDFLESIRKHSDKIGETAMKQAQQQRNLDNIVLQQPRI 240
KVMVDNIPKLREEIKDVSMSDLKDFLESIRKHSDKIGETAMKQAQQQRNLDNIVLQQPRI
Sbjct: 181 KVMVDNIPKLREEIKDVSMSDLKDFLESIRKHSDKIGETAMKQAQQQRNLDNIVLQQPRI 240
Query: 241 GSKRKSKKDAYIIFDTEIESTSPKSEQDSGILDVEDEEDDEEVPGAQDLVDFSPVYRCLH 300
GSKRKSKKDAYIIFDTEIESTSPKSEQDSGILDVEDEEDDEEVPGAQDLVDFSPVYRCLH
Sbjct: 241 GSKRKSKKDAYIIFDTEIESTSPKSEQDSGILDVEDEEDDEEVPGAQDLVDFSPVYRCLH 300
Query: 301 IYSVLGARETFENYYRKQRRKQARLVLQPPSNMHETLDGYRKYFNQIVGFFVVEDHILHT 360
IYSVLGARETFENYYRKQRRKQARLVLQPPSNMHETLDGYRKYFNQIVGFFVVEDHILHT
Sbjct: 301 IYSVLGARETFENYYRKQRRKQARLVLQPPSNMHETLDGYRKYFNQIVGFFVVEDHILHT 360
Query: 361 TQGLVNRAYIDELWEMALSKTIAALRTHSSYCSDPNLVLDLKNLIVLFADTLQVYGFPVN 420
TQGLVNRAYIDELWEMALSKTIAALRTHSSYCSDPNLVLDLKNLIVLFADTLQVYGFPVN
Sbjct: 361 TQGLVNRAYIDELWEMALSKTIAALRTHSSYCSDPNLVLDLKNLIVLFADTLQVYGFPVN 420
Query: 421 QLFDMLLEIRDQYSETLLKKWAGIFRNILDSDNYSPIPVTSEEMYKKVVGQFPFQDIELE 480
QLFDMLLEIRDQYSETLLKKWAGIFRNILDSDNYSPIPVTSEEMYKKVVGQFPFQDIELE
Sbjct: 421 QLFDMLLEIRDQYSETLLKKWAGIFRNILDSDNYSPIPVTSEEMYKKVVGQFPFQDIELE 480
Query: 481 KQPFPKKFPFSEFVPKVYNQIKEFIYACLKFSEDLHLSSTEVDDMIRKSTNLLLTRTLSN 540
KQPFPKKFPFSEFVPKVYNQIKEFIYACLKFSEDLHLSSTEVDDMIRKSTNLLLTRTLSN
Sbjct: 481 KQPFPKKFPFSEFVPKVYNQIKEFIYACLKFSEDLHLSSTEVDDMIRKSTNLLLTRTLSN 540
Query: 541 SLQNVIKRKNIGLTELVQIIINTTHLEKSCKYLEEFITNITNVLPETVHTTKLYGTTTFK 600
SLQNVIKRKNIGLTELVQIIINTTHLEKSCKYLEEFITNITNVLPETVHTTKLYGTTTFK
Sbjct: 541 SLQNVIKRKNIGLTELVQIIINTTHLEKSCKYLEEFITNITNVLPETVHTTKLYGTTTFK 600
Query: 601 DARHAAEEEIYTNLNQKIDQFLQLADYDWMTGDLGNKASDYLVDLIAFLRSTFAVFTHLP 660
DARHAAEEEIYTNLNQKIDQFLQLADYDWMTGDLGNKASDYLVDLIAFLRSTFAVFTHLP
Sbjct: 601 DARHAAEEEIYTNLNQKIDQFLQLADYDWMTGDLGNKASDYLVDLIAFLRSTFAVFTHLP 660
Query: 661 GKVAQTACMSACKHLATSLMQLLLEAEVRQLTLGALQQFNLDVRECEQFARSGPVPGFQE 720
GKVAQTACMSACKHLATSLMQLLLEAEVRQLTLGALQQFNLDVRECEQFARSGPVPGFQE
Sbjct: 661 GKVAQTACMSACKHLATSLMQLLLEAEVRQLTLGALQQFNLDVRECEQFARSGPVPGFQE 720
Query: 721 DTLQLAFIDLRQLLDLFIQWDWSTYLADYGQPNCKYLRVNPVTALTLLEKMKDTSRKNNM 780
DTLQLAFIDLRQLLDLFIQWDWSTYLADYGQPNCKYLRVNPVTALTLLEKMKDTSRKNNM
Sbjct: 721 DTLQLAFIDLRQLLDLFIQWDWSTYLADYGQPNCKYLRVNPVTALTLLEKMKDTSRKNNM 780
Query: 781 FAQFRKNERDKQKLIDTVAKQLRGLISSHHS 811
FAQFRKNERDKQKLIDTVAKQLRGLISSHHS
Sbjct: 781 FAQFRKNERDKQKLIDTVAKQLRGLISSHHS 811
>gi|65507403 SEC15-like 1 isoform a [Homo sapiens]
Length = 804
Score = 1165 bits (3013), Expect = 0.0
Identities = 581/805 (72%), Positives = 683/805 (84%), Gaps = 10/805 (1%)
Query: 6 MAE-AESLETAAEHERILREIESTDTACIGPTLRSVYDGEE--HGRFMEKLETRIRNHDR 62
MAE +ESL T EHERIL+EIESTDTAC+GPTLRSVYD + H +FMEKL+ IRNHD+
Sbjct: 1 MAENSESLGTVPEHERILQEIESTDTACVGPTLRSVYDDQPNAHKKFMEKLDACIRNHDK 60
Query: 63 EIEKMCNFHYQGFVDSITELLKVRGEAQKLKNQVTDTNRKLQHEGKELVIAMEELKQCRL 122
EIEKMCNFH+QGFVD+ITELLKVR +A+KLK QVTDTNR+ Q GKE+++ E++ +CR+
Sbjct: 61 EIEKMCNFHHQGFVDAITELLKVRTDAEKLKVQVTDTNRRFQDAGKEVIVHTEDIIRCRI 120
Query: 123 QQRNISATVDKLMLCLPVLEMYSKLRDQMKTKRHYPALKTLEHLEHTYLPQVSHYRFCKV 182
QQRNI+ V+KL LCLPVLEMYSKL++QM KR+Y ALKT+E LE+ Y P VS YRFC++
Sbjct: 121 QQRNITTVVEKLQLCLPVLEMYSKLKEQMSAKRYYSALKTMEQLENVYFPWVSQYRFCQL 180
Query: 183 MVDNIPKLREEIKDVSMSDLKDFLESIRKHSDKIGETAMKQAQQQRNLDNIVLQQPRIGS 242
M++N+PKLRE+IK++SMSDLKDFLESIRKHSDKIGETAMKQAQ Q+ + +Q +
Sbjct: 181 MIENLPKLREDIKEISMSDLKDFLESIRKHSDKIGETAMKQAQHQKTFSVSLQKQ----N 236
Query: 243 KRKSKKDAYIIFDTEIESTSPKSEQDSGILDVEDEEDDEEVPGAQDLVDFSPVYRCLHIY 302
K K K+ YI D E + + S L+ EDE ++EE+ QDLVDFSPVYRCLHIY
Sbjct: 237 KMKFGKNMYINRDRIPEERNETVLKHS--LEEEDE-NEEEILTVQDLVDFSPVYRCLHIY 293
Query: 303 SVLGARETFENYYRKQRRKQARLVLQPPSNMHETLDGYRKYFNQIVGFFVVEDHILHTTQ 362
SVLG ETFENYYRKQR+KQARLVLQP SNMHET+DGYR+YF QIVGFFVVEDHILH TQ
Sbjct: 294 SVLGDEETFENYYRKQRKKQARLVLQPQSNMHETVDGYRRYFTQIVGFFVVEDHILHVTQ 353
Query: 363 GLVNRAYIDELWEMALSKTIAALRTHSSYCSDPNLVLDLKNLIVLFADTLQVYGFPVNQL 422
GLV RAY DELW MALSK IA LR HSSYC+DP+LVL+LKNL V+FADTLQ YGFPVN+L
Sbjct: 354 GLVTRAYTDELWNMALSKIIAVLRAHSSYCTDPDLVLELKNLTVIFADTLQGYGFPVNRL 413
Query: 423 FDMLLEIRDQYSETLLKKWAGIFRNILDSDNYSPIPVTSEEMYKKVVGQFPFQDIELEKQ 482
FD+L EIRDQY+ETLLKKWAG+FR+I + DNYSPIPV +EE YK V+ +FPFQD +LEKQ
Sbjct: 414 FDLLFEIRDQYNETLLKKWAGVFRDIFEEDNYSPIPVVNEEEYKIVISKFPFQDPDLEKQ 473
Query: 483 PFPKKFPFSEFVPKVYNQIKEFIYACLKFSEDLHLSSTEVDDMIRKSTNLLLTRTLSNSL 542
FPKKFP S+ VP +Y Q+KEFIYA LKFSE LH SSTE+DDM+RKSTNLLLTRTLS+ L
Sbjct: 474 SFPKKFPMSQSVPHIYIQVKEFIYASLKFSESLHRSSTEIDDMLRKSTNLLLTRTLSSCL 533
Query: 543 QNVIKRKNIGLTELVQIIINTTHLEKSCKYLEEFITNITNVLPETVHTTKLYGTTTFKDA 602
N+I++ +IGLTELVQIIINTTHLE++CKYLE+FITNITN+ ETVHTT+LYG +TFKDA
Sbjct: 534 LNLIRKPHIGLTELVQIIINTTHLEQACKYLEDFITNITNISQETVHTTRLYGLSTFKDA 593
Query: 603 RHAAEEEIYTNLNQKIDQFLQLADYDWMTGDLGNKASDYLVDLIAFLRSTFAVFTHLPGK 662
RHAAE EIYT LNQKID+F+QLADYDW + +AS YL+DLI FLRS F VFTHLPGK
Sbjct: 594 RHAAEGEIYTKLNQKIDEFVQLADYDWTMSEPDGRASGYLMDLINFLRSIFQVFTHLPGK 653
Query: 663 VAQTACMSACKHLATSLMQLLLEAEVRQLTLGALQQFNLDVRECEQFARSGPVPGFQEDT 722
VAQTACMSAC+HL+TSLMQ+LL++E++Q+++GA+QQFNLDV +CE FA S PVPGFQ DT
Sbjct: 654 VAQTACMSACQHLSTSLMQMLLDSELKQISMGAVQQFNLDVIQCELFASSEPVPGFQGDT 713
Query: 723 LQLAFIDLRQLLDLFIQWDWSTYLADYGQPNCKYLRVNPVTALTLLEKMKDTSRKNNMFA 782
LQLAFIDLRQLLDLF+ WDWSTYLADYGQP KYLRVNP TALTLLEKMKDTS+KNN+FA
Sbjct: 714 LQLAFIDLRQLLDLFMVWDWSTYLADYGQPASKYLRVNPNTALTLLEKMKDTSKKNNIFA 773
Query: 783 QFRKNERDKQKLIDTVAKQLRGLIS 807
QFRKN+RDKQKLI+TV KQLR L++
Sbjct: 774 QFRKNDRDKQKLIETVVKQLRSLVN 798
>gi|62243652 SEC15-like 1 isoform b [Homo sapiens]
Length = 799
Score = 1129 bits (2920), Expect = 0.0
Identities = 564/797 (70%), Positives = 668/797 (83%), Gaps = 10/797 (1%)
Query: 13 ETAAEHERILREIESTDTACIGPTLRSVYDGEE--HGRFMEKLETRIRNHDREIEKMCNF 70
ET +E +L EI+S + + TLRSVYD + H +FMEKL+ IRNHD+EIEKMCNF
Sbjct: 5 ETDQTYENVLAEIQSFELP-VEATLRSVYDDQPNAHKKFMEKLDACIRNHDKEIEKMCNF 63
Query: 71 HYQGFVDSITELLKVRGEAQKLKNQVTDTNRKLQHEGKELVIAMEELKQCRLQQRNISAT 130
H+QGFVD+ITELLKVR +A+KLK QVTDTNR+ Q GKE+++ E++ +CR+QQRNI+
Sbjct: 64 HHQGFVDAITELLKVRTDAEKLKVQVTDTNRRFQDAGKEVIVHTEDIIRCRIQQRNITTV 123
Query: 131 VDKLMLCLPVLEMYSKLRDQMKTKRHYPALKTLEHLEHTYLPQVSHYRFCKVMVDNIPKL 190
V+KL LCLPVLEMYSKL++QM KR+Y ALKT+E LE+ Y P VS YRFC++M++N+PKL
Sbjct: 124 VEKLQLCLPVLEMYSKLKEQMSAKRYYSALKTMEQLENVYFPWVSQYRFCQLMIENLPKL 183
Query: 191 REEIKDVSMSDLKDFLESIRKHSDKIGETAMKQAQQQRNLDNIVLQQPRIGSKRKSKKDA 250
RE+IK++SMSDLKDFLESIRKHSDKIGETAMKQAQ Q+ + +Q +K K K+
Sbjct: 184 REDIKEISMSDLKDFLESIRKHSDKIGETAMKQAQHQKTFSVSLQKQ----NKMKFGKNM 239
Query: 251 YIIFDTEIESTSPKSEQDSGILDVEDEEDDEEVPGAQDLVDFSPVYRCLHIYSVLGARET 310
YI D E + + S L+ EDE ++EE+ QDLVDFSPVYRCLHIYSVLG ET
Sbjct: 240 YINRDRIPEERNETVLKHS--LEEEDE-NEEEILTVQDLVDFSPVYRCLHIYSVLGDEET 296
Query: 311 FENYYRKQRRKQARLVLQPPSNMHETLDGYRKYFNQIVGFFVVEDHILHTTQGLVNRAYI 370
FENYYRKQR+KQARLVLQP SNMHET+DGYR+YF QIVGFFVVEDHILH TQGLV RAY
Sbjct: 297 FENYYRKQRKKQARLVLQPQSNMHETVDGYRRYFTQIVGFFVVEDHILHVTQGLVTRAYT 356
Query: 371 DELWEMALSKTIAALRTHSSYCSDPNLVLDLKNLIVLFADTLQVYGFPVNQLFDMLLEIR 430
DELW MALSK IA LR HSSYC+DP+LVL+LKNL V+FADTLQ YGFPVN+LFD+L EIR
Sbjct: 357 DELWNMALSKIIAVLRAHSSYCTDPDLVLELKNLTVIFADTLQGYGFPVNRLFDLLFEIR 416
Query: 431 DQYSETLLKKWAGIFRNILDSDNYSPIPVTSEEMYKKVVGQFPFQDIELEKQPFPKKFPF 490
DQY+ETLLKKWAG+FR+I + DNYSPIPV +EE YK V+ +FPFQD +LEKQ FPKKFP
Sbjct: 417 DQYNETLLKKWAGVFRDIFEEDNYSPIPVVNEEEYKIVISKFPFQDPDLEKQSFPKKFPM 476
Query: 491 SEFVPKVYNQIKEFIYACLKFSEDLHLSSTEVDDMIRKSTNLLLTRTLSNSLQNVIKRKN 550
S+ VP +Y Q+KEFIYA LKFSE LH SSTE+DDM+RKSTNLLLTRTLS+ L N+I++ +
Sbjct: 477 SQSVPHIYIQVKEFIYASLKFSESLHRSSTEIDDMLRKSTNLLLTRTLSSCLLNLIRKPH 536
Query: 551 IGLTELVQIIINTTHLEKSCKYLEEFITNITNVLPETVHTTKLYGTTTFKDARHAAEEEI 610
IGLTELVQIIINTTHLE++CKYLE+FITNITN+ ETVHTT+LYG +TFKDARHAAE EI
Sbjct: 537 IGLTELVQIIINTTHLEQACKYLEDFITNITNISQETVHTTRLYGLSTFKDARHAAEGEI 596
Query: 611 YTNLNQKIDQFLQLADYDWMTGDLGNKASDYLVDLIAFLRSTFAVFTHLPGKVAQTACMS 670
YT LNQKID+F+QLADYDW + +AS YL+DLI FLRS F VFTHLPGKVAQTACMS
Sbjct: 597 YTKLNQKIDEFVQLADYDWTMSEPDGRASGYLMDLINFLRSIFQVFTHLPGKVAQTACMS 656
Query: 671 ACKHLATSLMQLLLEAEVRQLTLGALQQFNLDVRECEQFARSGPVPGFQEDTLQLAFIDL 730
AC+HL+TSLMQ+LL++E++Q+++GA+QQFNLDV +CE FA S PVPGFQ DTLQLAFIDL
Sbjct: 657 ACQHLSTSLMQMLLDSELKQISMGAVQQFNLDVIQCELFASSEPVPGFQGDTLQLAFIDL 716
Query: 731 RQLLDLFIQWDWSTYLADYGQPNCKYLRVNPVTALTLLEKMKDTSRKNNMFAQFRKNERD 790
RQLLDLF+ WDWSTYLADYGQP KYLRVNP TALTLLEKMKDTS+KNN+FAQFRKN+RD
Sbjct: 717 RQLLDLFMVWDWSTYLADYGQPASKYLRVNPNTALTLLEKMKDTSKKNNIFAQFRKNDRD 776
Query: 791 KQKLIDTVAKQLRGLIS 807
KQKLI+TV KQLR L++
Sbjct: 777 KQKLIETVVKQLRSLVN 793
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 43.5 bits (101), Expect = 8e-04
Identities = 54/214 (25%), Positives = 96/214 (44%), Gaps = 29/214 (13%)
Query: 86 RGEAQKLKNQVTDTNRKLQHEGKELVIAMEELKQCRLQQRNISATV----DKLMLCLPVL 141
R +L+NQ+ + K + E E+ +LK+ L+ T D++ L L
Sbjct: 965 RTSTLELQNQLDEYKEKNRRELAEM---QRQLKEKTLEAEKSRLTAMKMQDEMRLMEEEL 1021
Query: 142 EMYSKLRDQMKTKRHYPALKTLEHLEHTYLPQVSHYRFCKVMVDNIPKLREEIKDVSMSD 201
Y + +D+ TKR +TL+ LE+ L SH + D+ +L ++++D +S
Sbjct: 1022 RDYQRAQDEALTKRQLLE-QTLKDLEYE-LEAKSHLK------DDRSRLVKQMED-KVSQ 1072
Query: 202 LKDFLESIRKHSDKIGETAMKQAQQQRNLDNIVLQQ---------PRIGSKRKSKKDAYI 252
L+ LE R +SD + E + +Q L N +LQ+ +I +R++K
Sbjct: 1073 LEMELEEERNNSDLLSERISRSREQMEQLRNELLQERAARQDLECDKISLERQNKDLKSR 1132
Query: 253 IFDTEIESTSPKS----EQDSGILDVEDEEDDEE 282
I E S K + ++ I ++ED + EE
Sbjct: 1133 IIHLEGSYRSSKEGLVVQMEARIAELEDRLESEE 1166
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 42.4 bits (98), Expect = 0.002
Identities = 62/290 (21%), Positives = 130/290 (44%), Gaps = 31/290 (10%)
Query: 51 EKLETRIRNHDREIEKMCNFHYQGFVDSITELLKVRGEAQKLKNQVTDTNRKLQHEGKEL 110
E+LE + D E +++ + +S ++ ++ E Q L+ + N+ LQ +EL
Sbjct: 752 ERLEVSYQGLDIENQRL----QKTLENSNKKIQQLESELQDLEME----NQTLQKNLEEL 803
Query: 111 VIAMEELKQCRLQQRNISATVDKLMLCLPVLEMYSK-LRDQMKTK-----RHYPALKTLE 164
I+ + L+Q + +++ +L LE +K LR Q + K + + LE
Sbjct: 804 KISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLE 863
Query: 165 HLEHTYLPQVSHYRFCKVMVDNIPKLREEIKDVSMSDLKDFLESIRKH--SDKIGETAMK 222
T ++ Y+ V + + K +E+ + D+K L ++R+ S+K+ M
Sbjct: 864 KENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKT-LVTLREDLVSEKLKTQQMN 922
Query: 223 QAQQQ--RNLDNIVLQQPRIGSKRKSKKDAYIIFDTEIESTSPKSEQDSGILDVEDEEDD 280
++ L+ I L + R+ +S D Y + ++++EST KS L+++ +
Sbjct: 923 NDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKS------LEIK----E 972
Query: 281 EEVPGAQDLVDFSPVYRCLHIYSVLGARETFENYYRKQRRKQARLVLQPP 330
E++ + ++ S Y + ++ +E KQR+ + R+V P
Sbjct: 973 EKIAALEARLEESTNYNQQLRQELKTVKKNYEAL--KQRQDEERMVQSSP 1020
Score = 34.3 bits (77), Expect = 0.48
Identities = 36/157 (22%), Positives = 68/157 (43%), Gaps = 10/157 (6%)
Query: 81 ELLKVRGEAQKLKNQVTDTNRKLQHEGKELVIAMEELKQCRLQQRNISATVDKLMLCLPV 140
EL + + ++L+ ++ + +L +EL ELK RLQQ N++ D
Sbjct: 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELK--RLQQENMNLLSDARSA---- 305
Query: 141 LEMYSKLRDQMKTKRHYPALKTLEHLEHTYLPQVSHYRFCKVMVDNIPKLREEIKDVSMS 200
MY D ++ K + LE Y ++ F K V+ + + + + +
Sbjct: 306 -RMYRDELDALREKA--VRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTM 362
Query: 201 DLKDFLESIRKHSDKIGETAMKQAQQQRNLDNIVLQQ 237
L+D LE R SDK+ E + Q + L ++ +++
Sbjct: 363 -LEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMER 398
>gi|96975038 coiled-coil domain containing 100 [Homo sapiens]
Length = 986
Score = 41.6 bits (96), Expect = 0.003
Identities = 53/235 (22%), Positives = 101/235 (42%), Gaps = 24/235 (10%)
Query: 17 EHERILREIESTDTACIGPTLRSVYDGEEHGRFMEKLETRIRNHDREIEKMCNFHYQGFV 76
E E ++++ + T G +++ D E+ + + +E+ ++ +E++ + Q
Sbjct: 693 ERESLVKKKVAEYTILEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQ 752
Query: 77 DSITE-----LLKVRGEAQKLKNQVTDTNR---KLQHEGKELVIAMEELKQCRLQQRN-- 126
DSI + +V E K+K D +R +L + I +E +Q + QQ N
Sbjct: 753 DSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKP 812
Query: 127 -ISATVDKLMLCLPVLEMYSKLRDQMKTKRHYP-----ALKTLEHLEHTYLPQVSHYRFC 180
I + +L L +E+ KL K+K HY ALK L L+ Q S
Sbjct: 813 EIRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQR--EQESQMARL 870
Query: 181 KVMVDNIPKLR-----EEIKDVSMSDLKDFLESIRKHSDKIGETAMKQAQQQRNL 230
K + + ++R E KD ++ ++ L+ IR +++ + KQ Q +
Sbjct: 871 KKQQEELEQMRLRYLAAEEKDTVKTERQELLD-IRNELNRLRQQEQKQYQDSTEI 924
>gi|63252904 tropomyosin 1 alpha chain isoform 6 [Homo sapiens]
Length = 245
Score = 41.2 bits (95), Expect = 0.004
Identities = 54/232 (23%), Positives = 101/232 (43%), Gaps = 31/232 (13%)
Query: 9 AESLETAAEHERILREIESTDTACIGPTLRSVYDGEEHGRFMEKLETRIRNHDREIEKMC 68
A +L+ +HER LRE D A + ++ V EE R E+L T ++ + E EK
Sbjct: 28 AGTLQRELDHERKLRETAEADVASLNRRIQLV--EEELDRAQERLATALQKLE-EAEKAA 84
Query: 69 NFHYQGF--VDSITELLKVRGEAQKL-----KNQVTDTNRKLQHEGKELVIAMEELKQCR 121
+ +G ++S + + + E Q++ K+ D +RK + ++LVI +L++
Sbjct: 85 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 144
Query: 122 LQQRNISATVDKLMLCLPVLEMYSKLRDQMKTKRHYPALKTLEHLEHTYLPQVSHY-RFC 180
++ +S ++L +++KT + LK+LE Y + Y
Sbjct: 145 -ERAELSE------------GKCAELEEELKTVTN--NLKSLEAQAEKYSQKEDRYEEEI 189
Query: 181 KVMVDNIPKLREEIKDVSMSDLKDFLESIRKHSDKIGETAMKQAQQQRNLDN 232
KV+ D + + + S K + K D + + +Q +Q R L N
Sbjct: 190 KVLSDKLKEAETRAEFAERSVTK-----LEKSIDDLEDQLYQQLEQNRRLTN 236
>gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens]
Length = 1312
Score = 41.2 bits (95), Expect = 0.004
Identities = 30/102 (29%), Positives = 51/102 (50%), Gaps = 2/102 (1%)
Query: 181 KVMVDNIPKLREEIKDVSMSDLKDFLESIRKHSDKIGETAMKQAQQQRNLDNIVLQQPRI 240
K + D I + +E IK S+ K+ LESI HSD+ E +K+ + NLD+ R+
Sbjct: 453 KPIEDEIER-KENIKP-SLGSKKNLLESIPTHSDQEKEVNIKKPEDNENLDDKDDDTTRV 510
Query: 241 GSKRKSKKDAYIIFDTEIESTSPKSEQDSGILDVEDEEDDEE 282
K +A + T+ + ++D + E+EE++EE
Sbjct: 511 DESLNIKVEAEEEKAKSGDETNKEEDEDDEEAEEEEEEEEEE 552
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 40.8 bits (94), Expect = 0.005
Identities = 62/281 (22%), Positives = 117/281 (41%), Gaps = 42/281 (14%)
Query: 45 EHGRFMEKL-ETRIRNHDREIE-KMCNFHYQGFVDSITELLKVRGEAQKLKNQVTDTNRK 102
E + E L ET R+ +++ E K+ + H + ++I K+RG + N++++ +
Sbjct: 1701 ERDQLKENLRETITRDLEKQEELKIVHMHLKEHQETID---KLRGIVSEKTNEISNMQKD 1757
Query: 103 LQHEGKEL----VIAMEELKQCRLQQRNISATVDKLMLCLPVLEMYSKLRDQMKTKRHYP 158
L+H L + EEL+ + + T+DKL V E KL + K +
Sbjct: 1758 LEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGI--VSEKTDKLSNMQKDLENSN 1815
Query: 159 A-----LKTLEHLEHTYLPQVSHYRFCKVMVDNIPKLREEIKDVSMSDLK---------- 203
A ++ L+ EH + + V + +L+++IKD S++ K
Sbjct: 1816 AKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQ 1875
Query: 204 ------DFLESIRKHSD---------KIGETAMKQAQQQRNLDNIVLQQPRIGSKRKSKK 248
+ ++S+ K D K+ +K++ Q+ ++ +QQ + + R K
Sbjct: 1876 KLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQ-ELKTARMLSK 1934
Query: 249 DAYIIFDTEIESTSPKSEQDSGILDVEDEEDDEEVPGAQDL 289
+ D E S K+ Q S I D+ DE Q+L
Sbjct: 1935 EHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQEL 1975
Score = 30.0 bits (66), Expect = 9.0
Identities = 30/165 (18%), Positives = 74/165 (44%), Gaps = 30/165 (18%)
Query: 90 QKLKNQVTDTNRKLQHEGKELVIAMEELKQCRLQQRNISATVDKLMLCLPVLEMYSKLRD 149
Q +++++ + +LQ +E+ I ++E ++ + Q + D+L E+ +K+++
Sbjct: 1565 QSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLK--ENTKEIVAKMKE 1622
Query: 150 QMKTKRHYPALK------------TLEHLEHTYLPQ--------VSHYRFCKVMVDNIPK 189
++ Y LK +EHL+ + Q + R +++ +N+ +
Sbjct: 1623 SQ--EKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETENIRLTQILHENLEE 1680
Query: 190 LREEIKDVSMSDLKDFLESIRKHSDK----IGETAMKQAQQQRNL 230
+R K+ DL+ E+++ D+ + ET + ++Q L
Sbjct: 1681 MRSVTKE--RDDLRSVEETLKVERDQLKENLRETITRDLEKQEEL 1723
>gi|148664246 harmonin-interacting ankyrin-repeat containing protein
[Homo sapiens]
Length = 417
Score = 40.0 bits (92), Expect = 0.009
Identities = 34/117 (29%), Positives = 54/117 (46%), Gaps = 15/117 (12%)
Query: 191 REEIKDVSMSDLKDFLESIRKHSDKIGETAMKQAQQQRNLDNIVLQQPRIGSKRK---SK 247
REE +D S DF E ++ +++ G + + L +IV ++ RI S SK
Sbjct: 235 REEEED---SFSGDFKEKLQLSAEEDGSVHHESILNRPGLGSIVFRRNRISSPEDISDSK 291
Query: 248 KDAYIIFDTEIESTSPKSEQDSGILDVEDEE---------DDEEVPGAQDLVDFSPV 295
++ +E+ SE D G D E EE DD+EV +D+VD +P+
Sbjct: 292 REFGFKLPSELLQRQGASEADEGAADEEGEENGLKDDLPWDDDEVEWEEDVVDATPL 348
>gi|169214072 PREDICTED: zinc finger and SCAN domain containing 5C
[Homo sapiens]
Length = 495
Score = 38.9 bits (89), Expect = 0.019
Identities = 55/272 (20%), Positives = 106/272 (38%), Gaps = 42/272 (15%)
Query: 43 GEEHGRFMEKLETRIRNHDREIEKMCNFHYQGFV-----DSITELLKVRGEAQKLKNQVT 97
G E R M T++ NHD + E C+ +++ F D I L K+
Sbjct: 19 GSEPPRSMPSPATQLGNHDSDPET-CHVNFRMFSCPKESDPIQALRKLTELCHLWLRPDL 77
Query: 98 DTNRKLQHEGKELVIAMEELKQCRLQQRNISATVDKLMLCLPVLEMYSKLRDQMKTKRHY 157
T ++ ++ ME+ Q+ + ++ + C L D ++ R
Sbjct: 78 HTKEQILD-----MLVMEQFMISMPQELQVLVMMNGVQSC-------KDLEDLLRNNRRP 125
Query: 158 PALKTLEHLEHTYLPQVSHYRFCKVMVDNIPKLREEIKDVSMSDLKDFLESIRKHSDKIG 217
+ L YL Q S M + +R++ + VS + + +
Sbjct: 126 KKWSVVSFLGKEYLMQESDVE----MAEAPASVRDDPRHVSS-----------QRTSSVN 170
Query: 218 ETAMKQAQQQRNLDNIVLQQPRIGSKRKSKKDAYIIFDTEIESTSPKSEQDSGILDVEDE 277
+ ++ Q R L + PR+ + + + + +++ +T + PK+ + L+ + E
Sbjct: 171 QMCPEEGQASRELQTL----PRVPALFRRQDEDFLLPETTVMKGDPKALRPKPTLEKDLE 226
Query: 278 EDDEEVPGAQDLVDFSPVYRCLHIYSVLGARE 309
ED EE PG SP + + SV+GA+E
Sbjct: 227 EDREENPGLT-----SPEPQLPNSPSVVGAKE 253
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 38.5 bits (88), Expect = 0.025
Identities = 66/292 (22%), Positives = 117/292 (40%), Gaps = 33/292 (11%)
Query: 3 RGKMAEAESLET-AAEHERILREI------ESTDTACIGPTLRSVYDGEEHGRFMEKLET 55
R A+A+ LE + E IL+EI + +D C+ + EE + + +E
Sbjct: 1499 RSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLT--EELQKLQKDIEM 1556
Query: 56 RIRNHDREIEKMCNFHYQGFVDSITELLKVRGEAQKLKNQVTDTNRKLQHEGKELVIAME 115
RN D H Q +S L R E +KLK+QVT +++ ++L E
Sbjct: 1557 AERNEDH--------HLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKE 1608
Query: 116 ELKQCRLQQRNISATVD-KLMLCLPVLEMYSKLRDQMKTKRHYPALKTLEHLEHTYLPQV 174
EL LQ + A D + L L E+ K + K L+ L + Q+
Sbjct: 1609 ELH--LLQGSMVQAKADLQEALRLGETEVTEKCNHIREVK---SLLEELSFQKGELNVQI 1663
Query: 175 SHYRFCKVMVDNIPKLREEIKDVSMSDLKDFLESIRKHSDKIGETAMKQAQQQRNLDNIV 234
S + + +++EI + +L+ L + KH ++ + L +
Sbjct: 1664 SERK------TQLTLIKQEI-EKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLK 1716
Query: 235 LQQPRIGSKRKSKKDAYIIFDTEIESTSPKSEQDSGILDVED---EEDDEEV 283
LQ + S+ + + A + E+E+ S+Q G ++ + E D E+
Sbjct: 1717 LQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREI 1768
>gi|7656888 angiopoietin-like 3 precursor [Homo sapiens]
Length = 460
Score = 38.1 bits (87), Expect = 0.033
Identities = 33/142 (23%), Positives = 59/142 (41%), Gaps = 10/142 (7%)
Query: 492 EFVPKVYNQIKEFIYACLKFSEDLHLSSTEVDDMIRKSTNLLLTRTLSNSLQNVIKRKNI 551
+FV K QI + F + + S + ++ + L T +K ++
Sbjct: 59 DFVHKTKGQINDIFQKLNIFDQSFYDLSLQTSEIKEEEKELRRTTYKLQVKNEEVKNMSL 118
Query: 552 GL-TELVQIIINTTHLEKSCKYLEEFITNITNVLPETVHTTKLYGTTTF--------KDA 602
L ++L ++ L++ KYLEE +TN+ PET ++ TF KD
Sbjct: 119 ELNSKLESLLEEKILLQQKVKYLEEQLTNLIQNQPETPEHPEVTSLKTFVEKQDNSIKDL 178
Query: 603 RHAAEEEIYTNLNQKIDQFLQL 624
E++ Y LNQ+ Q ++
Sbjct: 179 LQTVEDQ-YKQLNQQHSQIKEI 199
>gi|109255234 centrosomal protein 290kDa [Homo sapiens]
Length = 2479
Score = 38.1 bits (87), Expect = 0.033
Identities = 46/239 (19%), Positives = 103/239 (43%), Gaps = 21/239 (8%)
Query: 43 GEEHGRFMEKLETRIRNHDREIEKMCNFHYQGFVDSI--TELLKVRGEAQKLKNQVTDTN 100
GEE +F +L+T++ + E+E M G E+ ++ + ++ ++ D
Sbjct: 77 GEEQAKFENQLKTKVMKLENELE-MAQQSAGGRDTRFLRNEICQLEKQLEQKDRELEDME 135
Query: 101 RKLQHEGK---ELVIAMEEL--KQCRLQQRNISATVDKLMLCLPVLEMYSKLRDQMKTKR 155
++L+ E K +L + EE + +L++ N LC +++ ++ Q +T
Sbjct: 136 KELEKEKKVNEQLALRNEEAENENSKLRRENKRLKKKNEQLCQDIIDYQKQIDSQKET-- 193
Query: 156 HYPALKTLEHLEHTYLPQVSHYRFCKVM-VDNIPKLREEIKDVSMSDLKDFLESIRKHSD 214
L + + Y Q+S + + +D I L E + + + + + +RK+ +
Sbjct: 194 ----LLSRRGEDSDYRSQLSKKNYELIQYLDEIQTLTEANEKIEVQN-----QEMRKNLE 244
Query: 215 KIGETAMKQAQQQRNLDNIVLQQPRIGSKRKSKKDAYIIFDTEI-ESTSPKSEQDSGIL 272
+ + K + + IV Q + + K + D Y + E+ + K+E+D I+
Sbjct: 245 ESVQEMEKMTDEYNRMKAIVHQTDNVIDQLKKENDHYQLQVQELTDLLKSKNEEDDPIM 303
Score = 30.0 bits (66), Expect = 9.0
Identities = 54/243 (22%), Positives = 102/243 (41%), Gaps = 31/243 (12%)
Query: 44 EEHGRFMEKLETRIRNHDREIEKMCN--FHYQGFVDSITE-LLKVRGEAQKLKNQVTDTN 100
EE KL + ++ E++C YQ +DS E LL RGE ++Q++ N
Sbjct: 153 EEAENENSKLRRENKRLKKKNEQLCQDIIDYQKQIDSQKETLLSRRGEDSDYRSQLSKKN 212
Query: 101 RKLQHEGKELVIAMEELKQCRLQ----QRNISATV-------DKLMLCLPVLEMYSKLRD 149
+L E+ E ++ +Q ++N+ +V D+ ++ + D
Sbjct: 213 YELIQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEKMTDEYNRMKAIVHQTDNVID 272
Query: 150 QMKTKR-HYPALKTLEHLEHTYLPQVSHYRFCKVMVDNIPKLRE-----EIKDVSMSDLK 203
Q+K + HY L+ E T L + + +MV K+ E KD + + +
Sbjct: 273 QLKKENDHYQ----LQVQELTDLLKSKNEEDDPIMVAVNAKVEEWKLILSSKDDEIIEYQ 328
Query: 204 DFLESIRKH-------SDKIGETAMKQAQQQRNLDNIVLQQPRIGSKRKSKKDAYIIFDT 256
L ++R+ +DK A++Q Q+R+ +L + ++ +K+ II D
Sbjct: 329 QMLHNLREKLKNAQLDADKSNVMALQQGIQERDSQIKMLTEQVEQYTKEMEKNTCIIEDL 388
Query: 257 EIE 259
+ E
Sbjct: 389 KNE 391
>gi|4885583 Rho-associated, coiled-coil containing protein kinase 1
[Homo sapiens]
Length = 1354
Score = 37.7 bits (86), Expect = 0.043
Identities = 53/266 (19%), Positives = 111/266 (41%), Gaps = 18/266 (6%)
Query: 38 RSVYDGEEHGRFMEKLETRIRNHDR--EIEKMCNFHYQGFVDSITELLKVRGEAQKLKNQ 95
+SV E + E+ E R + +R +IEK C+ S +L + G ++++++
Sbjct: 709 KSVAMCEMEKKLKEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTGNKERMEDE 768
Query: 96 VTDTNRKLQHEGKELVIAMEELKQCRLQQRNISATVDKLMLCLPVLEMYSKLRD---QMK 152
V + +L+ E + ++ ELK + N+ ++ + L +L +
Sbjct: 769 VKNLTLQLEQESNKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQL 828
Query: 153 TKRHYPALKTLEHLEHTYLPQVSHYRFCKVMVDNIPKLREEIKDVSMSDLKDFLESIRKH 212
TK++ + L+ + Y F + + +L+EEI++ + +LK E +
Sbjct: 829 TKQYRGNEGQMRELQDQL--EAEQY-FSTLYKTQVKELKEEIEEKNRENLKKIQELQNEK 885
Query: 213 SD-----KIGETAMKQAQQQRNLDNIVLQQPRIGSKRKSKKDAYIIFD-----TEIESTS 262
+ ET + Q R L + SK+ + ++ I D + +E +
Sbjct: 886 ETLATQLDLAETKAESEQLARGLLEEQYFELTQESKKAASRNRQEITDKDHTVSRLEEAN 945
Query: 263 PKSEQDSGILDVEDEEDDEEVPGAQD 288
+D IL E+EE E++ A++
Sbjct: 946 SMLTKDIEILRRENEELTEKMKKAEE 971
>gi|56961680 coiled-coil domain containing 147 [Homo sapiens]
Length = 872
Score = 37.7 bits (86), Expect = 0.043
Identities = 78/400 (19%), Positives = 155/400 (38%), Gaps = 52/400 (13%)
Query: 9 AESLETAAEHERILREIESTDTACIGPTLRSVYDGEEHGRFMEKLETRIRNHDREIEKMC 68
A++ E E ER E E + + + R EKLE ++ +++
Sbjct: 177 AQTTEQQQETERSKEEAEHAISQFQQEIQQRQNEASREFRKKEKLEKELKQIQADMDSR- 235
Query: 69 NFHYQGFVDSITELL-KVRGEAQKLKNQVTDT-----------------NRKLQHEGKEL 110
Q + ++ + + K + E QKL+ Q+ + N KLQ E ++
Sbjct: 236 ----QTEIKALQQYVQKSKEELQKLEQQLKEQKILNERAAKELEQFQMRNAKLQQENEQH 291
Query: 111 VIAMEELKQCRLQQR-NISATVDKLMLCLPVLEMYSKLRDQMKTKRHYPALKTLEHLEHT 169
+ E+L Q Q+ + A +++ + +K+R+Q+ K H H E
Sbjct: 292 SLVCEQLSQENQQKALELKAKEEEVHQMRLDIGKLNKIREQIHKKLH--------HTEDQ 343
Query: 170 YLPQVSHYRFCKVMVDNIPKLREEIKDVSMSDLKDFLESIRKHSDKIGETAMKQAQQQRN 229
H K + + + E K + D K E +R+ D + + +K +
Sbjct: 344 KAEVEQHKETLKNQIVGLEREVEASKKQAELDRKAMDELLRER-DILNKNMLKAVNATQK 402
Query: 230 LDNIVLQQPRIGSKRKSKKDAYIIFDTEIESTSPKSEQDSGILDVEDEEDDEEVPGAQDL 289
++V K + A + EI++ ++++ I+ ++E D + A DL
Sbjct: 403 QTDLV----------KLHEQAKRNLEGEIQNYKDEAQKQRKIIFHLEKERDRYINQASDL 452
Query: 290 VDFSPVYRCLHIYSVLGARETFENYYRKQRRKQARLVLQPPSNMHETLDGYRKYFNQIVG 349
+ L + RET YRK + ++ + L+ N++E + R +++
Sbjct: 453 TQ-----KVLMNMEDIKVRETQIFDYRK-KIAESEIKLKQQQNLYEAVRSDRNLYSK--N 504
Query: 350 FFVVEDHILHTTQGL-VNRAYIDELWEMALSKTIAALRTH 388
+D I + L + +DEL E +K A ++ H
Sbjct: 505 LVEAQDEITDMKRKLKIMIHQVDELKEDISAKESALVKLH 544
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 37.4 bits (85), Expect = 0.056
Identities = 73/347 (21%), Positives = 133/347 (38%), Gaps = 68/347 (19%)
Query: 5 KMAEAESLETAAEHERILREIESTDTACIGPTLRSVYDGEEHGRFMEKLETRIRNHDREI 64
K E E LE + E +E + G LR+ E + ++E ++ D E+
Sbjct: 1533 KQLEVEKLELQSALEEAEASLEHEE----GKILRAQL---EFNQIKAEIERKLAEKDEEM 1585
Query: 65 EKMCNFHYQGFVDSI-----------TELLKVR----GEAQKLKNQVTDTNRKLQHEGKE 109
E+ H Q VDS+ E+L+V+ G+ +++ Q++ NR K+
Sbjct: 1586 EQAKRNH-QRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQ 1644
Query: 110 LVIAMEELKQCRLQ-----------QRNISATVDKLMLCLPVLEMYSKLRDQMKTKR--- 155
+ LK ++Q + NI+ + L LE + +Q + R
Sbjct: 1645 VKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLA 1704
Query: 156 HYPALKTLEHLEHTYLPQVSHYRFCKVMVDNIPKLREEIKDV-------------SMSDL 202
++T E ++ + S K M ++ +L+ E+++ +++D
Sbjct: 1705 EQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDA 1764
Query: 203 KDFLESIRKHSDKIG--ETAMKQAQQ-----QRNLDNIVLQQPRIGSKRKSKKDAYII-F 254
E ++K D E K +Q Q LD + G K+ K +A +
Sbjct: 1765 AMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVREL 1824
Query: 255 DTEIESTSP----------KSEQDSGILDVEDEEDDEEVPGAQDLVD 291
+ E+E+ KSE+ L + EED + + QDLVD
Sbjct: 1825 EGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVD 1871
>gi|169214427 PREDICTED: zinc finger and SCAN domain containing 5C
[Homo sapiens]
Length = 495
Score = 36.6 bits (83), Expect = 0.096
Identities = 53/272 (19%), Positives = 107/272 (39%), Gaps = 42/272 (15%)
Query: 43 GEEHGRFMEKLETRIRNHDREIEKMCNFHYQGFV-----DSITELLKVRGEAQKLKNQVT 97
G E + M T++ NHD + E C+ +++ F D I L K+
Sbjct: 19 GSEPPQSMPSPATQLGNHDSDPET-CHVNFRMFSCPKESDPIQALRKLTELCHLWLRPDL 77
Query: 98 DTNRKLQHEGKELVIAMEELKQCRLQQRNISATVDKLMLCLPVLEMYSKLRDQMKTKRHY 157
T ++ ++ ME+ Q+ + ++ + C L D ++ R
Sbjct: 78 HTKEQILD-----MLVMEQFMISMPQELQVLVMMNGVQSC-------KDLEDLLRNNRRP 125
Query: 158 PALKTLEHLEHTYLPQVSHYRFCKVMVDNIPKLREEIKDVSMSDLKDFLESIRKHSDKIG 217
+ L YL Q S M + +R++ + VS + + +
Sbjct: 126 KKWSVVSFLGKEYLMQESDVE----MAEAPASVRDDPRHVSS-----------QRTSSVN 170
Query: 218 ETAMKQAQQQRNLDNIVLQQPRIGSKRKSKKDAYIIFDTEIESTSPKSEQDSGILDVEDE 277
+ ++ Q + L + PR+ + + +++ +++ +T + PK+ + L+ + E
Sbjct: 171 QMCPEEGQASQELQTL----PRVPALFRRQEEDFLLPETTVMKGDPKALRPKPTLEKDLE 226
Query: 278 EDDEEVPGAQDLVDFSPVYRCLHIYSVLGARE 309
ED EE PG SP + + SV+GA+E
Sbjct: 227 EDREENPGLT-----SPEPQLPNSPSVVGAKE 253
>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
Length = 1088
Score = 35.8 bits (81), Expect = 0.16
Identities = 62/294 (21%), Positives = 126/294 (42%), Gaps = 40/294 (13%)
Query: 7 AEAESLETAAEH--------ERILREIESTDTACIGPTLRSVYDGEEHGRFMEKLETRIR 58
A+ ++L+T E ER LR++E S + EE + ME R
Sbjct: 375 AKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVY----R 430
Query: 59 NHDREIEKMCNFHYQGFVDSITELLKVRGEAQKLKNQVTDTNRKLQHEGKELVIAMEELK 118
+H + ++ Q TELL ++ + + L NQ +D+ + ++ + E L
Sbjct: 431 SHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIE-------VLKESLT 483
Query: 119 QCRLQQRNISATVDKLMLCLPVLE-MYSKLRDQMKTKRHYPALKTLEHLEHTYLPQVSHY 177
+ + VD L L L E M +K Q++ + E + + V
Sbjct: 484 AKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKE- 542
Query: 178 RFCKVMVDNIPKLREEIKD--VSMSDLKDFLESIRKHSDKIGETAMKQ-----AQQQRNL 230
R V+ I L+E+++D MS LK+ ++S++ + +TA+ A+++R +
Sbjct: 543 RKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNT-DTALTTLEEALAEKERTI 601
Query: 231 DNIVLQQPRIGSKRKSKKDAYIIFDTEIESTSPK--------SEQDSGILDVED 276
+ + Q+ R +++ + D Y +++ K SE+++ +LD+++
Sbjct: 602 ERLKEQRDRDEREKQEEIDNY---KKDLKDLKEKVSLLQGDLSEKEASLLDLKE 652
>gi|19924131 RAD50 homolog isoform 2 [Homo sapiens]
Length = 1173
Score = 35.8 bits (81), Expect = 0.16
Identities = 60/311 (19%), Positives = 116/311 (37%), Gaps = 51/311 (16%)
Query: 17 EHERILREIESTDTACIGPTLRSVYDGEEHGRFMEKLETRIRNHDREIEKMCNFHYQGFV 76
E E L +I D R +++ EK+E + D ++ + + H +
Sbjct: 118 EIEHNLSKIMKLDNEIKALDSRKKQMEKDNSELEEKMEKVFQGTDEQLNDLYHNHQRTVR 177
Query: 77 DSITELLKVRGEAQKLKNQVTDTNRKLQHEGKELVIAMEELK-QCRLQQRNISATVDKLM 135
+ +L+ E +KL + +R L E EL++ L+ Q Q +I A D L+
Sbjct: 178 EKERKLVDCHRELEKLNKE----SRLLNQEKSELLVEQGRLQLQADRHQEHIRAR-DSLI 232
Query: 136 LCL------------PVLEMYSKLRDQMKTKRHYPALKTLEHLEHTYL-------PQVSH 176
L P E K ++ +R KT L + + Q+
Sbjct: 233 QSLATQLELDGFERGPFSERQIKNFHKLVRERQEGEAKTANQLMNDFAEKETLKQKQIDE 292
Query: 177 YRFCKVMVDNIPKLREEIKDVSMSDLKDF---LESIRKHSDKI---------GETAMKQA 224
R K + I +L+ EI ++LK+ L+ + SD+I E + +A
Sbjct: 293 IRDKKTGLGRIIELKSEILSKKQNELKNVKYELQQLEGSSDRILELDQELIKAERELSKA 352
Query: 225 QQQRNLDNIVLQQPRIGSKRKSKKDAYIIFDTEIES--------------TSPKSEQDSG 270
++ N++ + ++ + +++ D E+E T K+++D
Sbjct: 353 EKNSNVETLKMEVISLQNEKADLDRTLRKLDQEMEQLNHHTTTRTQMEMLTKDKADKDEQ 412
Query: 271 ILDVEDEEDDE 281
I ++ DE
Sbjct: 413 IRKIKSRHSDE 423
>gi|19924129 RAD50 homolog isoform 1 [Homo sapiens]
Length = 1312
Score = 35.8 bits (81), Expect = 0.16
Identities = 60/311 (19%), Positives = 116/311 (37%), Gaps = 51/311 (16%)
Query: 17 EHERILREIESTDTACIGPTLRSVYDGEEHGRFMEKLETRIRNHDREIEKMCNFHYQGFV 76
E E L +I D R +++ EK+E + D ++ + + H +
Sbjct: 257 EIEHNLSKIMKLDNEIKALDSRKKQMEKDNSELEEKMEKVFQGTDEQLNDLYHNHQRTVR 316
Query: 77 DSITELLKVRGEAQKLKNQVTDTNRKLQHEGKELVIAMEELK-QCRLQQRNISATVDKLM 135
+ +L+ E +KL + +R L E EL++ L+ Q Q +I A D L+
Sbjct: 317 EKERKLVDCHRELEKLNKE----SRLLNQEKSELLVEQGRLQLQADRHQEHIRAR-DSLI 371
Query: 136 LCL------------PVLEMYSKLRDQMKTKRHYPALKTLEHLEHTYL-------PQVSH 176
L P E K ++ +R KT L + + Q+
Sbjct: 372 QSLATQLELDGFERGPFSERQIKNFHKLVRERQEGEAKTANQLMNDFAEKETLKQKQIDE 431
Query: 177 YRFCKVMVDNIPKLREEIKDVSMSDLKDF---LESIRKHSDKI---------GETAMKQA 224
R K + I +L+ EI ++LK+ L+ + SD+I E + +A
Sbjct: 432 IRDKKTGLGRIIELKSEILSKKQNELKNVKYELQQLEGSSDRILELDQELIKAERELSKA 491
Query: 225 QQQRNLDNIVLQQPRIGSKRKSKKDAYIIFDTEIES--------------TSPKSEQDSG 270
++ N++ + ++ + +++ D E+E T K+++D
Sbjct: 492 EKNSNVETLKMEVISLQNEKADLDRTLRKLDQEMEQLNHHTTTRTQMEMLTKDKADKDEQ 551
Query: 271 ILDVEDEEDDE 281
I ++ DE
Sbjct: 552 IRKIKSRHSDE 562
>gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]
Length = 1233
Score = 35.8 bits (81), Expect = 0.16
Identities = 43/198 (21%), Positives = 91/198 (45%), Gaps = 19/198 (9%)
Query: 88 EAQKLKNQVTDTNRKLQHEGKELVIAMEELKQCRLQQRNISATVDKLMLCLPVLEMYSKL 147
E +KL ++ N++++ + K + +ELK+ + + + K+M +E K
Sbjct: 234 EIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKE-------LGKMMREQQQIEKEIKE 286
Query: 148 RDQMKTKRHYPALKTLEHLEHTYLPQVSHYRFCKVMVDNIPKLREEIKDVSMSDLKDFLE 207
+D ++ +K E+ H ++ K + N K ++ K M +L+ +
Sbjct: 287 KDSELNQKRPQYIKAKENTSH----KIKKLEAAKKSLQNAQKHYKKRKG-DMDELEKEML 341
Query: 208 SIRKHSDKIGETAMKQAQQQ-RNL---DNIVLQQPRIGSKRKSKKDAYIIFDTEIESTSP 263
S+ K + E +++Q Q R+L +N V + R+ + SK+ A + + E +
Sbjct: 342 SVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRL-KEEASKRAATLAQELEKFNRDQ 400
Query: 264 KSEQDSGILDVEDEEDDE 281
K++QD LD+E+ + E
Sbjct: 401 KADQDR--LDLEERKKVE 416
Score = 30.4 bits (67), Expect = 6.9
Identities = 34/143 (23%), Positives = 57/143 (39%), Gaps = 36/143 (25%)
Query: 2 ERGKMAEAESLETAAEHERILREIESTDTACIGPTLRSVYDGEEHGRFMEKLETRIRNHD 61
+R + E + +ET A+ ++ LREIE E+ + +EKLE I
Sbjct: 405 DRLDLEERKKVETEAKIKQKLREIE------------------ENQKRIEKLEEYITTSK 446
Query: 62 REIEKMCNFHYQGFVDSITELLKVRGEAQKLKNQVTDTNRKLQHEGKELVIAMEELKQCR 121
+ +E E K+ GE L +V R++ KEL ME+L R
Sbjct: 447 QSLE---------------EQKKLEGE---LTEEVEMAKRRIDEINKELNQVMEQLGDAR 488
Query: 122 LQQRNISATVDKLMLCLPVLEMY 144
+ ++ S K + + +Y
Sbjct: 489 IDRQESSRQQRKAEIMESIKRLY 511
>gi|148727333 adenylate kinase 7 [Homo sapiens]
Length = 723
Score = 35.8 bits (81), Expect = 0.16
Identities = 39/159 (24%), Positives = 64/159 (40%), Gaps = 36/159 (22%)
Query: 219 TAMKQAQQQRNLDNI---VLQQPRIGSKRKSK-------------KDAYIIFDTEIESTS 262
T +K+ +Q R L I +L P +G +K KD ++E+
Sbjct: 354 TILKEYKQSRGLMPIKICILGPPAVGKSSIAKELANYYKLHHIQLKDVISEAIAKLEAIV 413
Query: 263 PKSEQDSGILDVEDEEDDEEVPGAQDLVDFSPVYRCLHIYSVLGARETFENYYRKQ---- 318
++ G +VE+EE++E V AQ+L+D G +E+ E +
Sbjct: 414 APNDVGEGEEEVEEEEEEENVEDAQELLD--------------GIKESMEQNAGQLDDQY 459
Query: 319 --RRKQARLVLQPPSNMHETLDGYRKYFNQIVGFFVVED 355
R + +L P N LDG+ K ++Q F ED
Sbjct: 460 IIRFMKEKLKSMPCRNQGYILDGFPKTYDQAKDLFNQED 498
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 35.4 bits (80), Expect = 0.21
Identities = 58/273 (21%), Positives = 109/273 (39%), Gaps = 42/273 (15%)
Query: 54 ETRIRNHDREIEKMCNFHYQGFVDSITELLKVRGEAQKLKNQVTDTNRKLQHEGKELVIA 113
ETR RN ++K ++ ++ EAQK + + Q + + V A
Sbjct: 1604 ETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRA 1663
Query: 114 MEELKQ--CRLQQRN--ISATVDKLMLCLPVLEMYSKLRDQMKTKRHYPALKTLEHLEHT 169
++LK+ +++RN + A +++L + E KL +Q ++T E ++
Sbjct: 1664 NDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQ-------ELIETSERVQLL 1716
Query: 170 YLPQVSHYRFCKVMVDNIPKLREEIKDV-------------SMSDLKDFLESIRKHSDKI 216
+ S K M ++ +L+ E+++ +++D E ++K D
Sbjct: 1717 HSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTS 1776
Query: 217 G--ETAMKQAQQ-----QRNLDNIVLQQPRIGSKRKSKKDAYI-IFDTEIESTSP----- 263
E K +Q Q LD + G K+ K +A + + E+E+
Sbjct: 1777 AHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAES 1836
Query: 264 -----KSEQDSGILDVEDEEDDEEVPGAQDLVD 291
KSE+ L + EED + + QDLVD
Sbjct: 1837 VKGMRKSERRIKELTYQTEEDRKNLLRLQDLVD 1869
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 35.4 bits (80), Expect = 0.21
Identities = 43/194 (22%), Positives = 84/194 (43%), Gaps = 24/194 (12%)
Query: 73 QGFVDSITELL--------KVRGEAQKLKNQVTDTNRKLQHEGKELVIAMEELKQCRLQQ 124
Q V+S+T +L K+ + L +Q+ DT LQ E ++ + +L+Q ++
Sbjct: 1286 QNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEER 1345
Query: 125 RNISATVDKLMLCLPVLEMY-SKLRDQM--KTKRHYPALKTLEHLEHTYLPQVSHYRFCK 181
++ +D+ M LE + S L Q+ K+ T+E LE RF K
Sbjct: 1346 NSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEE------GKKRFQK 1399
Query: 182 VMVDNIPKLREEIK------DVSMSDLKDFLESIRKHSDKIGETAMKQAQQQRNLDNIVL 235
++N+ + EE + + + L+ L+ + D + ++QR D ++
Sbjct: 1400 -EIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 1458
Query: 236 QQPRIGSKRKSKKD 249
++ I SK ++D
Sbjct: 1459 EEKNISSKYADERD 1472
Score = 32.7 bits (73), Expect = 1.4
Identities = 49/226 (21%), Positives = 99/226 (43%), Gaps = 19/226 (8%)
Query: 7 AEAESLETAAEHERILREIEST-DTACIGPTLRSVYDGEEHGRFMEKLETRIRNHDREIE 65
AE + + E E + E+E T D+ LR+ + +E + L+ R+H+ +++
Sbjct: 1137 AEKQKRDLGEELEALKTELEDTLDSTATQQELRAKRE-QEVTVLKKALDEETRSHEAQVQ 1195
Query: 66 KMCNFHYQGFVDSITELLKVRGEAQKLKNQVTDTNRKLQHEGKELVIAMEELKQCRLQQR 125
+M H Q V+ +TE L+ + ++ K + + L+ E +L + L Q + +
Sbjct: 1196 EMRQKHAQA-VEELTEQLE---QFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVE 1251
Query: 126 NISATVDKLMLCLPVLEMYSKLRDQMKTKRHYPALKTLEHLEHTYLPQVSHYRFCKVMVD 185
+ K L V E+ SK D + + L H + V+
Sbjct: 1252 H-----KKKKLEAQVQELQSKCSDGERARAE---LNDKVHKLQNEVESVT--GMLNEAEG 1301
Query: 186 NIPKLREEIKDVSMSDLKDFLESIRKHS-DKIG-ETAMKQAQQQRN 229
KL +++ +S S L+D E +++ + K+ T ++Q +++RN
Sbjct: 1302 KAIKLAKDVASLS-SQLQDTQELLQEETRQKLNVSTKLRQLEEERN 1346
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 35.4 bits (80), Expect = 0.21
Identities = 43/194 (22%), Positives = 84/194 (43%), Gaps = 24/194 (12%)
Query: 73 QGFVDSITELL--------KVRGEAQKLKNQVTDTNRKLQHEGKELVIAMEELKQCRLQQ 124
Q V+S+T +L K+ + L +Q+ DT LQ E ++ + +L+Q ++
Sbjct: 1293 QNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEER 1352
Query: 125 RNISATVDKLMLCLPVLEMY-SKLRDQM--KTKRHYPALKTLEHLEHTYLPQVSHYRFCK 181
++ +D+ M LE + S L Q+ K+ T+E LE RF K
Sbjct: 1353 NSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEE------GKKRFQK 1406
Query: 182 VMVDNIPKLREEIK------DVSMSDLKDFLESIRKHSDKIGETAMKQAQQQRNLDNIVL 235
++N+ + EE + + + L+ L+ + D + ++QR D ++
Sbjct: 1407 -EIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 1465
Query: 236 QQPRIGSKRKSKKD 249
++ I SK ++D
Sbjct: 1466 EEKNISSKYADERD 1479
Score = 32.7 bits (73), Expect = 1.4
Identities = 49/226 (21%), Positives = 99/226 (43%), Gaps = 19/226 (8%)
Query: 7 AEAESLETAAEHERILREIEST-DTACIGPTLRSVYDGEEHGRFMEKLETRIRNHDREIE 65
AE + + E E + E+E T D+ LR+ + +E + L+ R+H+ +++
Sbjct: 1144 AEKQKRDLGEELEALKTELEDTLDSTATQQELRAKRE-QEVTVLKKALDEETRSHEAQVQ 1202
Query: 66 KMCNFHYQGFVDSITELLKVRGEAQKLKNQVTDTNRKLQHEGKELVIAMEELKQCRLQQR 125
+M H Q V+ +TE L+ + ++ K + + L+ E +L + L Q + +
Sbjct: 1203 EMRQKHAQA-VEELTEQLE---QFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVE 1258
Query: 126 NISATVDKLMLCLPVLEMYSKLRDQMKTKRHYPALKTLEHLEHTYLPQVSHYRFCKVMVD 185
+ K L V E+ SK D + + L H + V+
Sbjct: 1259 H-----KKKKLEAQVQELQSKCSDGERARAE---LNDKVHKLQNEVESVT--GMLNEAEG 1308
Query: 186 NIPKLREEIKDVSMSDLKDFLESIRKHS-DKIG-ETAMKQAQQQRN 229
KL +++ +S S L+D E +++ + K+ T ++Q +++RN
Sbjct: 1309 KAIKLAKDVASLS-SQLQDTQELLQEETRQKLNVSTKLRQLEEERN 1353
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 35.4 bits (80), Expect = 0.21
Identities = 43/194 (22%), Positives = 84/194 (43%), Gaps = 24/194 (12%)
Query: 73 QGFVDSITELL--------KVRGEAQKLKNQVTDTNRKLQHEGKELVIAMEELKQCRLQQ 124
Q V+S+T +L K+ + L +Q+ DT LQ E ++ + +L+Q ++
Sbjct: 1293 QNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEER 1352
Query: 125 RNISATVDKLMLCLPVLEMY-SKLRDQM--KTKRHYPALKTLEHLEHTYLPQVSHYRFCK 181
++ +D+ M LE + S L Q+ K+ T+E LE RF K
Sbjct: 1353 NSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEE------GKKRFQK 1406
Query: 182 VMVDNIPKLREEIK------DVSMSDLKDFLESIRKHSDKIGETAMKQAQQQRNLDNIVL 235
++N+ + EE + + + L+ L+ + D + ++QR D ++
Sbjct: 1407 -EIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 1465
Query: 236 QQPRIGSKRKSKKD 249
++ I SK ++D
Sbjct: 1466 EEKNISSKYADERD 1479
Score = 32.7 bits (73), Expect = 1.4
Identities = 49/226 (21%), Positives = 99/226 (43%), Gaps = 19/226 (8%)
Query: 7 AEAESLETAAEHERILREIEST-DTACIGPTLRSVYDGEEHGRFMEKLETRIRNHDREIE 65
AE + + E E + E+E T D+ LR+ + +E + L+ R+H+ +++
Sbjct: 1144 AEKQKRDLGEELEALKTELEDTLDSTATQQELRAKRE-QEVTVLKKALDEETRSHEAQVQ 1202
Query: 66 KMCNFHYQGFVDSITELLKVRGEAQKLKNQVTDTNRKLQHEGKELVIAMEELKQCRLQQR 125
+M H Q V+ +TE L+ + ++ K + + L+ E +L + L Q + +
Sbjct: 1203 EMRQKHAQA-VEELTEQLE---QFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVE 1258
Query: 126 NISATVDKLMLCLPVLEMYSKLRDQMKTKRHYPALKTLEHLEHTYLPQVSHYRFCKVMVD 185
+ K L V E+ SK D + + L H + V+
Sbjct: 1259 H-----KKKKLEAQVQELQSKCSDGERARAE---LNDKVHKLQNEVESVT--GMLNEAEG 1308
Query: 186 NIPKLREEIKDVSMSDLKDFLESIRKHS-DKIG-ETAMKQAQQQRN 229
KL +++ +S S L+D E +++ + K+ T ++Q +++RN
Sbjct: 1309 KAIKLAKDVASLS-SQLQDTQELLQEETRQKLNVSTKLRQLEEERN 1353
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 35.4 bits (80), Expect = 0.21
Identities = 43/194 (22%), Positives = 84/194 (43%), Gaps = 24/194 (12%)
Query: 73 QGFVDSITELL--------KVRGEAQKLKNQVTDTNRKLQHEGKELVIAMEELKQCRLQQ 124
Q V+S+T +L K+ + L +Q+ DT LQ E ++ + +L+Q ++
Sbjct: 1286 QNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEER 1345
Query: 125 RNISATVDKLMLCLPVLEMY-SKLRDQM--KTKRHYPALKTLEHLEHTYLPQVSHYRFCK 181
++ +D+ M LE + S L Q+ K+ T+E LE RF K
Sbjct: 1346 NSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEE------GKKRFQK 1399
Query: 182 VMVDNIPKLREEIK------DVSMSDLKDFLESIRKHSDKIGETAMKQAQQQRNLDNIVL 235
++N+ + EE + + + L+ L+ + D + ++QR D ++
Sbjct: 1400 -EIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 1458
Query: 236 QQPRIGSKRKSKKD 249
++ I SK ++D
Sbjct: 1459 EEKNISSKYADERD 1472
Score = 32.7 bits (73), Expect = 1.4
Identities = 49/226 (21%), Positives = 99/226 (43%), Gaps = 19/226 (8%)
Query: 7 AEAESLETAAEHERILREIEST-DTACIGPTLRSVYDGEEHGRFMEKLETRIRNHDREIE 65
AE + + E E + E+E T D+ LR+ + +E + L+ R+H+ +++
Sbjct: 1137 AEKQKRDLGEELEALKTELEDTLDSTATQQELRAKRE-QEVTVLKKALDEETRSHEAQVQ 1195
Query: 66 KMCNFHYQGFVDSITELLKVRGEAQKLKNQVTDTNRKLQHEGKELVIAMEELKQCRLQQR 125
+M H Q V+ +TE L+ + ++ K + + L+ E +L + L Q + +
Sbjct: 1196 EMRQKHAQA-VEELTEQLE---QFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVE 1251
Query: 126 NISATVDKLMLCLPVLEMYSKLRDQMKTKRHYPALKTLEHLEHTYLPQVSHYRFCKVMVD 185
+ K L V E+ SK D + + L H + V+
Sbjct: 1252 H-----KKKKLEAQVQELQSKCSDGERARAE---LNDKVHKLQNEVESVT--GMLNEAEG 1301
Query: 186 NIPKLREEIKDVSMSDLKDFLESIRKHS-DKIG-ETAMKQAQQQRN 229
KL +++ +S S L+D E +++ + K+ T ++Q +++RN
Sbjct: 1302 KAIKLAKDVASLS-SQLQDTQELLQEETRQKLNVSTKLRQLEEERN 1346
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 35.0 bits (79), Expect = 0.28
Identities = 72/343 (20%), Positives = 130/343 (37%), Gaps = 79/343 (23%)
Query: 10 ESLETAAEHE--RILREIESTDTACIGPTLRSVYDGEEHGRFMEKLETRIRNHDREIEKM 67
E E A EHE +ILR I+ T R + + +E ++E RN+ R +E M
Sbjct: 1546 EEAEAALEHEEAKILR-IQLELTQVKSEIDRKIAEKDE------EIEQLKRNYQRTVETM 1598
Query: 68 ---CNFHYQGFVDSITELLKVRGEAQKLKNQVTDTNRKLQHEGKELVIAMEELKQCRL-- 122
+ + ++I K+ G+ +++ Q++ NR+ K L +LK +L
Sbjct: 1599 QSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHL 1658
Query: 123 -------------------QQRNISATVDKLMLCLPVLEMYSKLRDQMKTKRHYPALKTL 163
+ + A V++L L E KL +Q L +
Sbjct: 1659 DDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQ-------ELLDSN 1711
Query: 164 EHLEHTYLPQVSHYRFCKVMVDNIPKLREEIKDVS-------------MSDLKDFLESIR 210
E ++ + S K + ++ +L+ E++D S ++D E ++
Sbjct: 1712 ERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELK 1771
Query: 211 KHSDKIGETAMKQAQQQRNLDNIVLQ-QPRI---------GSKRKSKKDAYIIFDTEIES 260
K D T+ + ++NL+ V Q R+ G K++ +K I + E E
Sbjct: 1772 KEQD----TSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFEL 1827
Query: 261 TSPKSEQDSGI------------LDVEDEEDDEEVPGAQDLVD 291
+ + + L + EED + V QDLVD
Sbjct: 1828 EGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVD 1870
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 35.0 bits (79), Expect = 0.28
Identities = 58/292 (19%), Positives = 114/292 (39%), Gaps = 14/292 (4%)
Query: 2 ERGKMAEAESLETAAEHERILREIESTDTACIGPTLRSVYDGEEHGRFMEKLE-TRIRNH 60
E+ + A E LE A + E A + ++++ E R + E +R++
Sbjct: 406 EKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQE 465
Query: 61 DREIEKMCNFHYQGFVDSITELLKVRGEAQKLKNQVTDTNRKLQHEGKELVIAMEE---- 116
++ K + + + E R E Q+L ++ R+ Q + K +A+E+
Sbjct: 466 VVDVMKKSSEEQIAKLQKLHEKELARKE-QELTKKLQTREREFQEQMK---VALEKSQSE 521
Query: 117 ---LKQCRLQQRNISATVDKLMLCLPVLEMYSKLRDQMKTKRHYPA--LKTLEHLEHTYL 171
+ Q + QQ +++ +L + E +KLRD + Y L+ LE +
Sbjct: 522 YLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQ 581
Query: 172 PQVSHYRFCKVMVDNIPKLREEIKDVSMSDLKDFLESIRKHSDKIGETAMKQAQQQRNLD 231
+ + V ++ + V + K LES++ D + ++ +QQ +
Sbjct: 582 ENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTE 641
Query: 232 NIVLQQPRIGSKRKSKKDAYIIFDTEIESTSPKSEQDSGILDVEDEEDDEEV 283
L++ K KD IIF IE + K+ + + E E E+
Sbjct: 642 MEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSEL 693
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.386
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,470,264
Number of Sequences: 37866
Number of extensions: 1248217
Number of successful extensions: 4973
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 108
Number of HSP's that attempted gapping in prelim test: 4817
Number of HSP's gapped (non-prelim): 278
length of query: 811
length of database: 18,247,518
effective HSP length: 111
effective length of query: 700
effective length of database: 14,044,392
effective search space: 9831074400
effective search space used: 9831074400
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.