Search of human proteins with 14916498

Search of human proteins with 14916498

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|14916498 osteoglycin preproprotein [Homo sapiens]
         (298 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7661704 osteoglycin preproprotein [Homo sapiens]                   597   e-171
gi|14916498 osteoglycin preproprotein [Homo sapiens]                  597   e-171
gi|68800360 dermatan sulfate proteoglycan 3 precursor [Homo sapi...   231   4e-61
gi|7657419 opticin precursor [Homo sapiens]                           211   5e-55
gi|4505047 lumican precursor [Homo sapiens]                            87   2e-17
gi|4826876 osteomodulin [Homo sapiens]                                 81   1e-15
gi|19743846 decorin isoform a preproprotein [Homo sapiens]             80   3e-15
gi|4503271 decorin isoform a preproprotein [Homo sapiens]              80   3e-15
gi|11321571 slit homolog 3 [Homo sapiens]                              78   8e-15
gi|41349454 proline arginine-rich end leucine-rich repeat protei...    74   1e-13
gi|4506041 proline arginine-rich end leucine-rich repeat protein...    74   1e-13
gi|41350214 asporin [Homo sapiens]                                     73   3e-13
gi|226342935 podocan-like 1 isoform 3 [Homo sapiens]                   72   6e-13
gi|5901992 keratocan [Homo sapiens]                                    72   6e-13
gi|45505137 podocan [Homo sapiens]                                     71   1e-12
gi|86990456 leucine rich repeat transmembrane neuronal 1 [Homo s...    70   2e-12
gi|71040111 fibromodulin precursor [Homo sapiens]                      70   2e-12
gi|156139147 leucine rich repeat transmembrane neuronal 4 isofor...    67   1e-11
gi|197927168 leucine rich repeat transmembrane neuronal 4 isofor...    67   1e-11
gi|188528675 slit homolog 1 [Homo sapiens]                             65   7e-11
gi|153251229 chondroadherin precursor [Homo sapiens]                   64   2e-10
gi|4759146 slit homolog 2 [Homo sapiens]                               62   8e-10
gi|76880480 hypothetical protein LOC9865 [Homo sapiens]                61   1e-09
gi|109809759 leucine rich repeat transmembrane neuronal 3 [Homo ...    60   2e-09
gi|226342933 podocan-like 1 isoform 2 [Homo sapiens]                   60   3e-09
gi|226342931 podocan-like 1 isoform 1 [Homo sapiens]                   60   3e-09
gi|40217820 slit and trk like 3 protein [Homo sapiens]                 60   3e-09
gi|4502403 biglycan preproprotein [Homo sapiens]                       59   4e-09
gi|126517478 peroxidasin homolog-like [Homo sapiens]                   59   4e-09
gi|27436867 slit and trk like 4 protein [Homo sapiens]                 59   4e-09

>gi|7661704 osteoglycin preproprotein [Homo sapiens]
          Length = 298

 Score =  597 bits (1538), Expect = e-171
 Identities = 298/298 (100%), Positives = 298/298 (100%)

Query: 1   MKTLQSTLLLLLLVPLIKPAPPTQQDSRIIYDYGTDNFEESIFSQDYEDKYLDGKNIKEK 60
           MKTLQSTLLLLLLVPLIKPAPPTQQDSRIIYDYGTDNFEESIFSQDYEDKYLDGKNIKEK
Sbjct: 1   MKTLQSTLLLLLLVPLIKPAPPTQQDSRIIYDYGTDNFEESIFSQDYEDKYLDGKNIKEK 60

Query: 61  ETVIIPNEKSLQLQKDEAITPLPPKKENDEMPTCLLCVCLSGSVYCEEVDIDAVPPLPKE 120
           ETVIIPNEKSLQLQKDEAITPLPPKKENDEMPTCLLCVCLSGSVYCEEVDIDAVPPLPKE
Sbjct: 61  ETVIIPNEKSLQLQKDEAITPLPPKKENDEMPTCLLCVCLSGSVYCEEVDIDAVPPLPKE 120

Query: 121 SAYLYARFNKIKKLTAKDFADIPNLRRLDFTGNLIEDIEDGTFSKLSLLEELSLAENQLL 180
           SAYLYARFNKIKKLTAKDFADIPNLRRLDFTGNLIEDIEDGTFSKLSLLEELSLAENQLL
Sbjct: 121 SAYLYARFNKIKKLTAKDFADIPNLRRLDFTGNLIEDIEDGTFSKLSLLEELSLAENQLL 180

Query: 181 KLPVLPPKLTLFNAKYNKIKSRGIKANAFKKLNNLTFLYLDHNALESVPLNLPESLRVIH 240
           KLPVLPPKLTLFNAKYNKIKSRGIKANAFKKLNNLTFLYLDHNALESVPLNLPESLRVIH
Sbjct: 181 KLPVLPPKLTLFNAKYNKIKSRGIKANAFKKLNNLTFLYLDHNALESVPLNLPESLRVIH 240

Query: 241 LQFNNIASITDDTFCKANDTSYIRDRIEEIRLEGNPIVLGKHPNSFICLKRLPIGSYF 298
           LQFNNIASITDDTFCKANDTSYIRDRIEEIRLEGNPIVLGKHPNSFICLKRLPIGSYF
Sbjct: 241 LQFNNIASITDDTFCKANDTSYIRDRIEEIRLEGNPIVLGKHPNSFICLKRLPIGSYF 298


>gi|14916498 osteoglycin preproprotein [Homo sapiens]
          Length = 298

 Score =  597 bits (1538), Expect = e-171
 Identities = 298/298 (100%), Positives = 298/298 (100%)

Query: 1   MKTLQSTLLLLLLVPLIKPAPPTQQDSRIIYDYGTDNFEESIFSQDYEDKYLDGKNIKEK 60
           MKTLQSTLLLLLLVPLIKPAPPTQQDSRIIYDYGTDNFEESIFSQDYEDKYLDGKNIKEK
Sbjct: 1   MKTLQSTLLLLLLVPLIKPAPPTQQDSRIIYDYGTDNFEESIFSQDYEDKYLDGKNIKEK 60

Query: 61  ETVIIPNEKSLQLQKDEAITPLPPKKENDEMPTCLLCVCLSGSVYCEEVDIDAVPPLPKE 120
           ETVIIPNEKSLQLQKDEAITPLPPKKENDEMPTCLLCVCLSGSVYCEEVDIDAVPPLPKE
Sbjct: 61  ETVIIPNEKSLQLQKDEAITPLPPKKENDEMPTCLLCVCLSGSVYCEEVDIDAVPPLPKE 120

Query: 121 SAYLYARFNKIKKLTAKDFADIPNLRRLDFTGNLIEDIEDGTFSKLSLLEELSLAENQLL 180
           SAYLYARFNKIKKLTAKDFADIPNLRRLDFTGNLIEDIEDGTFSKLSLLEELSLAENQLL
Sbjct: 121 SAYLYARFNKIKKLTAKDFADIPNLRRLDFTGNLIEDIEDGTFSKLSLLEELSLAENQLL 180

Query: 181 KLPVLPPKLTLFNAKYNKIKSRGIKANAFKKLNNLTFLYLDHNALESVPLNLPESLRVIH 240
           KLPVLPPKLTLFNAKYNKIKSRGIKANAFKKLNNLTFLYLDHNALESVPLNLPESLRVIH
Sbjct: 181 KLPVLPPKLTLFNAKYNKIKSRGIKANAFKKLNNLTFLYLDHNALESVPLNLPESLRVIH 240

Query: 241 LQFNNIASITDDTFCKANDTSYIRDRIEEIRLEGNPIVLGKHPNSFICLKRLPIGSYF 298
           LQFNNIASITDDTFCKANDTSYIRDRIEEIRLEGNPIVLGKHPNSFICLKRLPIGSYF
Sbjct: 241 LQFNNIASITDDTFCKANDTSYIRDRIEEIRLEGNPIVLGKHPNSFICLKRLPIGSYF 298


>gi|68800360 dermatan sulfate proteoglycan 3 precursor [Homo
           sapiens]
          Length = 322

 Score =  231 bits (590), Expect = 4e-61
 Identities = 127/325 (39%), Positives = 194/325 (59%), Gaps = 34/325 (10%)

Query: 1   MKTLQSTLLLLLLVPLIKPAPPTQQDSRIIYDYGTDNFEESIFSQD----YEDKYLDGKN 56
           MKTL   +L L++      AP  +       +Y ++ ++ ++   D    YE+  +D   
Sbjct: 1   MKTLAGLVLGLVIFDAAVTAPTLES-----INYDSETYDATLEDLDNLYNYENIPVDKVE 55

Query: 57  IK--------EKETVIIPN--EKSLQLQKDEAITPL------PPKKE---------NDEM 91
           I+         +E +  P   EK+ + +++E  TP       P + E         N++ 
Sbjct: 56  IEIATVMPSGNRELLTPPPQPEKAQEEEEEEESTPRLIDGSSPQEPEFTGVLGPHTNEDF 115

Query: 92  PTCLLCVCLSGSVYCEEVDIDAVPPLPKESAYLYARFNKIKKLTAKDFADIPNLRRLDFT 151
           PTCLLC C+S +VYC++ ++DA+PPLPK +AY Y+RFN+IKK+   DFA + +L+R+D T
Sbjct: 116 PTCLLCTCISTTVYCDDHELDAIPPLPKNTAYFYSRFNRIKKINKNDFASLSDLKRIDLT 175

Query: 152 GNLIEDIEDGTFSKLSLLEELSLAENQLLKLPVLPPKLTLFNAKYNKIKSRGIKANAFKK 211
            NLI +I++  F KL  L EL L +N++ +LP LP  LT  +   N++  +GIK  AFK 
Sbjct: 176 SNLISEIDEDAFRKLPQLRELVLRDNKIRQLPELPTTLTFIDISNNRLGRKGIKQEAFKD 235

Query: 212 LNNLTFLYLDHNALESVPLNLPESLRVIHLQFNNIASITDDTFCKANDTSYIRDRIEEIR 271
           + +L  LYL  N L+ +PL LPE+LR +HLQ NNI  + +DTFC   + +YIR  +E+IR
Sbjct: 236 MYDLHHLYLTDNNLDHIPLPLPENLRALHLQNNNILEMHEDTFCNVKNLTYIRKALEDIR 295

Query: 272 LEGNPIVLGKHPNSFICLKRLPIGS 296
           L+GNPI L K P +++CL RLP+GS
Sbjct: 296 LDGNPINLSKTPQAYMCLPRLPVGS 320


>gi|7657419 opticin precursor [Homo sapiens]
          Length = 332

 Score =  211 bits (538), Expect = 5e-55
 Identities = 108/278 (38%), Positives = 162/278 (58%), Gaps = 16/278 (5%)

Query: 36  DNFEESIFSQDYEDKYLDGKNIKEKETVIIPNEKSLQLQKDEAITPLPPK---------- 85
           DN+ E I   +YE+    G  + E +   +    S+   K       P            
Sbjct: 54  DNYGEVIDLSNYEELTDYGDQLPEVKVTSLAPATSISPAKSTTAPGTPSSNPTMTRPTTA 113

Query: 86  ------KENDEMPTCLLCVCLSGSVYCEEVDIDAVPPLPKESAYLYARFNKIKKLTAKDF 139
                 + N  +PTCL+CVCL  SVYC+++D++ +PPLP+ +AYLYARFN+I ++ A+DF
Sbjct: 114 GLLLSSQPNHGLPTCLVCVCLGSSVYCDDIDLEDIPPLPRRTAYLYARFNRISRIRAEDF 173

Query: 140 ADIPNLRRLDFTGNLIEDIEDGTFSKLSLLEELSLAENQLLKLPVLPPKLTLFNAKYNKI 199
             +  L+R+D + NLI  I++  F  L  L++L L ENQL  LPVLP  +   + + N++
Sbjct: 174 KGLTKLKRIDLSNNLISSIDNDAFRLLHALQDLILPENQLEALPVLPSGIEFLDVRLNRL 233

Query: 200 KSRGIKANAFKKLNNLTFLYLDHNALESVPLNLPESLRVIHLQFNNIASITDDTFCKAND 259
           +S GI+  AF+ +  L FLYL  N L+S+P  LP SLR +HLQ N I ++  D FC   +
Sbjct: 234 QSSGIQPAAFRAMEKLQFLYLSDNLLDSIPGPLPLSLRSVHLQNNLIETMQRDVFCDPEE 293

Query: 260 TSYIRDRIEEIRLEGNPIVLGKHPNSFICLKRLPIGSY 297
             + R ++E+IRL+GNPI L   P+++ CL RLPIG +
Sbjct: 294 HKHTRRQLEDIRLDGNPINLSLFPSAYFCLPRLPIGRF 331


>gi|4505047 lumican precursor [Homo sapiens]
          Length = 338

 Score = 86.7 bits (213), Expect = 2e-17
 Identities = 62/210 (29%), Positives = 100/210 (47%), Gaps = 26/210 (12%)

Query: 92  PTCLLCVCLSGSVYCEEVDIDAVPPLPKESAYLYARFNKIKKLTAKDFADIPNLRRLDFT 151
           P C        ++YC+E+ + +VP +P    YLY R N+I  +  K F ++ +L+ L   
Sbjct: 39  PECNCPESYPSAMYCDELKLKSVPMVPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILD 98

Query: 152 GNLIED--IEDGTFSKLSLLEELSLAENQLLKLPVLPPK--------------------- 188
            NL+E+  I+   FSKL  L++L +  N L +     PK                     
Sbjct: 99  HNLLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKLGSFEGL 158

Query: 189 --LTLFNAKYNKIKSRGIKANAFKKLNNLTFLYLDHNALESVPLNLPESLRVIHLQFNNI 246
             LT  + ++N++K   + A AFK L +L +L L  N +  +P  LP SL  ++L  N I
Sbjct: 159 VNLTFIHLQHNRLKEDAVSA-AFKGLKSLEYLDLSFNQIARLPSGLPVSLLTLYLDNNKI 217

Query: 247 ASITDDTFCKANDTSYIRDRIEEIRLEGNP 276
           ++I D+ F + N   Y+R    E+   G P
Sbjct: 218 SNIPDEYFKRFNALQYLRLSHNELADSGIP 247


>gi|4826876 osteomodulin [Homo sapiens]
          Length = 421

 Score = 80.9 bits (198), Expect = 1e-15
 Identities = 57/190 (30%), Positives = 88/190 (46%), Gaps = 30/190 (15%)

Query: 97  CVC---LSGSVYCEEVDIDAVPPLPKESAYLYARFNKIKKLTAKDFADIPNLRRLDFTGN 153
           C C      S+YC+   +  +P +P     LY +FN+I+ +TA  F +  +L+ ++ + N
Sbjct: 66  CFCPTNFPSSMYCDNRKLKTIPNIPMHIQQLYLQFNEIEAVTANSFINATHLKEINLSHN 125

Query: 154 LI--EDIEDGTFSKLSLLEELSLAENQLLKLPVLPPK----------------------- 188
            I  + I+ G F+KL  L +L L  N L + P   PK                       
Sbjct: 126 KIKSQKIDYGVFAKLPNLLQLHLEHNNLEEFPFPLPKSLERLLLGYNEISKLQTNAMDGL 185

Query: 189 --LTLFNAKYNKIKSRGIKANAFKKLNNLTFLYLDHNALESVPLNLPESLRVIHLQFNNI 246
             LT+ +  YN +    +K   F K+  L  L L  N LES+P  LP SL  + L+ N+I
Sbjct: 186 VNLTMLDLCYNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGLPSSLMYLSLENNSI 245

Query: 247 ASITDDTFCK 256
           +SI +  F K
Sbjct: 246 SSIPEKYFDK 255



 Score = 65.5 bits (158), Expect = 6e-11
 Identities = 51/178 (28%), Positives = 80/178 (44%), Gaps = 15/178 (8%)

Query: 104 VYCEEVDIDAVP-PLPKESAYLYARFNKIKKLTAKDFADIPNLRRLDFTGNLIED--IED 160
           ++ E  +++  P PLPK    L   +N+I KL       + NL  LD   N + D  ++D
Sbjct: 146 LHLEHNNLEEFPFPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYLHDSLLKD 205

Query: 161 GTFSKLSLLEELSLAENQLLKLPV-LPPKLTLFNAKYNKIKSRGIKANAFKKLNNLTFLY 219
             F+K+  L +L+L  N+L  +P  LP  L   + + N I S  I    F KL  L  L 
Sbjct: 206 KIFAKMEKLMQLNLCSNRLESMPPGLPSSLMYLSLENNSISS--IPEKYFDKLPKLHTLR 263

Query: 220 LDHNALESVPLNLPESLRVIHLQFNNIASITDDTFCKANDTSYIRDRIEEIRLEGNPI 277
           + HN L+ +P N+     ++ L   +          K     YI   +E + L+ N I
Sbjct: 264 MSHNKLQDIPYNIFNLPNIVELSVGH---------NKLKQAFYIPRNLEHLYLQNNEI 312



 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 32/121 (26%), Positives = 57/121 (47%), Gaps = 6/121 (4%)

Query: 111 IDAVPP-LPKESAYLYARFNKIKKLTAKDFADIPNLRRLDFTGNLIEDIEDGTFSKLSLL 169
           ++++PP LP    YL    N I  +  K F  +P L  L  + N ++DI    F+ L  +
Sbjct: 224 LESMPPGLPSSLMYLSLENNSISSIPEKYFDKLPKLHTLRMSHNKLQDIPYNIFN-LPNI 282

Query: 170 EELSLAENQLLKLPVLPPKLTLFNAKYNKIKSRGIKANAFK----KLNNLTFLYLDHNAL 225
            ELS+  N+L +   +P  L     + N+I+   +            ++LT++ +D N L
Sbjct: 283 VELSVGHNKLKQAFYIPRNLEHLYLQNNEIEKMNLTVMCPSIDPLHYHHLTYIRVDQNKL 342

Query: 226 E 226
           +
Sbjct: 343 K 343



 Score = 37.7 bits (86), Expect = 0.012
 Identities = 22/75 (29%), Positives = 40/75 (53%), Gaps = 8/75 (10%)

Query: 203 GIKANAFKKLNNLTFLYLDHNALESVPLNLPESLRVIHLQFNNIASITDDTFCKANDTSY 262
           G  +  F   N  + +Y D+  L+++P N+P  ++ ++LQFN I ++T ++F  A     
Sbjct: 61  GCVSECFCPTNFPSSMYCDNRKLKTIP-NIPMHIQQLYLQFNEIEAVTANSFINAT---- 115

Query: 263 IRDRIEEIRLEGNPI 277
               ++EI L  N I
Sbjct: 116 ---HLKEINLSHNKI 127


>gi|19743846 decorin isoform a preproprotein [Homo sapiens]
          Length = 359

 Score = 79.7 bits (195), Expect = 3e-15
 Identities = 54/185 (29%), Positives = 84/185 (45%), Gaps = 27/185 (14%)

Query: 92  PTC-LLCVCLSGSVYCEEVDIDAVPP-LPKESAYLYARFNKIKKLTAKDFADIPNLRRLD 149
           P C   C C    V C ++ +D VP  LP ++  L  + NKI ++   DF ++ NL  L 
Sbjct: 52  PVCPFRCQCHLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALI 111

Query: 150 FTGNLIEDIEDGTFSKLSLLEELSLAENQLLKLPVLPPK--------------------- 188
              N I  +  G F+ L  LE L L++NQL +LP   PK                     
Sbjct: 112 LVNNKISKVSPGAFTPLVKLERLYLSKNQLKELPEKMPKTLQELRAHENEITKVRKVTFN 171

Query: 189 ----LTLFNAKYNKIKSRGIKANAFKKLNNLTFLYLDHNALESVPLNLPESLRVIHLQFN 244
               + +     N +KS GI+  AF+ +  L+++ +    + S+P  LP SL  +HL  N
Sbjct: 172 GLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGN 231

Query: 245 NIASI 249
            I+ +
Sbjct: 232 KISRV 236



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 47/195 (24%), Positives = 78/195 (40%), Gaps = 39/195 (20%)

Query: 119 KESAYLYARFNKIKKLTAKDFADI----------PNLRRLDFTGNLIEDIEDGTFSKLSL 168
           K S      F  +KKL+    AD           P+L  L   GN I  ++  +   L+ 
Sbjct: 187 KSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDAASLKGLNN 246

Query: 169 LEELSLAENQLLKLPVLPPKLTLFNAKYNKIKSRGIKANAFKKLNNLTFLYLDHNALESV 228
           L +L L+ N +  +                    G  AN      +L  L+LD+N L  V
Sbjct: 247 LAKLGLSFNSISAV------------------DNGSLANT----PHLRELHLDNNKLTRV 284

Query: 229 PLNLPES--LRVIHLQFNNIASITDDTFCKANDTSYIRDRIEEIRLEGNPIVLGK-HPNS 285
           P  L E   ++V++L  NNI+ +    FC     +  +     + L  NP+   +  P++
Sbjct: 285 PGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTK-KASYSGVSLFSNPVQYWEIQPST 343

Query: 286 FICL---KRLPIGSY 297
           F C+     + +G+Y
Sbjct: 344 FRCVYVRSAIQLGNY 358


>gi|4503271 decorin isoform a preproprotein [Homo sapiens]
          Length = 359

 Score = 79.7 bits (195), Expect = 3e-15
 Identities = 54/185 (29%), Positives = 84/185 (45%), Gaps = 27/185 (14%)

Query: 92  PTC-LLCVCLSGSVYCEEVDIDAVPP-LPKESAYLYARFNKIKKLTAKDFADIPNLRRLD 149
           P C   C C    V C ++ +D VP  LP ++  L  + NKI ++   DF ++ NL  L 
Sbjct: 52  PVCPFRCQCHLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALI 111

Query: 150 FTGNLIEDIEDGTFSKLSLLEELSLAENQLLKLPVLPPK--------------------- 188
              N I  +  G F+ L  LE L L++NQL +LP   PK                     
Sbjct: 112 LVNNKISKVSPGAFTPLVKLERLYLSKNQLKELPEKMPKTLQELRAHENEITKVRKVTFN 171

Query: 189 ----LTLFNAKYNKIKSRGIKANAFKKLNNLTFLYLDHNALESVPLNLPESLRVIHLQFN 244
               + +     N +KS GI+  AF+ +  L+++ +    + S+P  LP SL  +HL  N
Sbjct: 172 GLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGN 231

Query: 245 NIASI 249
            I+ +
Sbjct: 232 KISRV 236



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 47/195 (24%), Positives = 78/195 (40%), Gaps = 39/195 (20%)

Query: 119 KESAYLYARFNKIKKLTAKDFADI----------PNLRRLDFTGNLIEDIEDGTFSKLSL 168
           K S      F  +KKL+    AD           P+L  L   GN I  ++  +   L+ 
Sbjct: 187 KSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDAASLKGLNN 246

Query: 169 LEELSLAENQLLKLPVLPPKLTLFNAKYNKIKSRGIKANAFKKLNNLTFLYLDHNALESV 228
           L +L L+ N +  +                    G  AN      +L  L+LD+N L  V
Sbjct: 247 LAKLGLSFNSISAV------------------DNGSLANT----PHLRELHLDNNKLTRV 284

Query: 229 PLNLPES--LRVIHLQFNNIASITDDTFCKANDTSYIRDRIEEIRLEGNPIVLGK-HPNS 285
           P  L E   ++V++L  NNI+ +    FC     +  +     + L  NP+   +  P++
Sbjct: 285 PGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTK-KASYSGVSLFSNPVQYWEIQPST 343

Query: 286 FICL---KRLPIGSY 297
           F C+     + +G+Y
Sbjct: 344 FRCVYVRSAIQLGNY 358


>gi|11321571 slit homolog 3 [Homo sapiens]
          Length = 1523

 Score = 78.2 bits (191), Expect = 8e-15
 Identities = 57/166 (34%), Positives = 82/166 (49%), Gaps = 10/166 (6%)

Query: 97  CVCLSGSVYCEEVDIDAVPP-LPKESAYLYARFNKIKKLTAKDFADIPNLRRLDFTGNLI 155
           C C + SV C  + + AVP  +P+ +  L    N I ++T  DFA + NLR L    N +
Sbjct: 38  CTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQV 97

Query: 156 EDIEDGTFSKLSLLEELSLAENQLLKLPVL----PPKLTLFNAKYNKIKSRGIKANAFKK 211
             IE G F  L  LE L L +N+L  LP L     PKLT  +   N+I  +GI   AF+ 
Sbjct: 98  SVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQI--QGIPRKAFRG 155

Query: 212 LNNLTFLYLDHN---ALESVPLNLPESLRVIHLQFNNIASITDDTF 254
           + ++  L LD+N    +E         L ++ L  NNI+ I   +F
Sbjct: 156 ITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSF 201



 Score = 60.1 bits (144), Expect = 2e-09
 Identities = 54/190 (28%), Positives = 84/190 (44%), Gaps = 26/190 (13%)

Query: 73  LQKDEAITPLPPKKENDEMPTCLL--------CVCLSGSVYCEEVDIDAVPP-LPKESAY 123
           +QK E + P P    + E P+C          C C +  V C    +  +P  LP+    
Sbjct: 256 VQKKEYVCPAP----HSEPPSCNANSISCPSPCTCSNNIVDCRGKGLMEIPANLPEGIVE 311

Query: 124 LYARFNKIKKLTAKDFADIPNLRRLDFTGNLIEDIEDGTFSKLSLLEELSLAENQLLKLP 183
           +    N IK + A  F     L+R+D + N I DI    F  L  L  L L  N++ ++ 
Sbjct: 312 IRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIA 371

Query: 184 ------VLPPKLTLFNAKYNKIKSRGIKANAFKKLNNLTFLYLDHNALESVPLNL---PE 234
                 ++  +L L NA  NKI    ++ N F+ L NL  L L  N L+++   L    +
Sbjct: 372 KGLFDGLVSLQLLLLNA--NKINC--LRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQ 427

Query: 235 SLRVIHLQFN 244
           S++ +HL  N
Sbjct: 428 SIQTLHLAQN 437



 Score = 45.4 bits (106), Expect = 6e-05
 Identities = 41/163 (25%), Positives = 67/163 (41%), Gaps = 27/163 (16%)

Query: 97  CVCLSGSVYCEEVDIDAVPP-LPKESAYLYARFNKIKKLTAKD-FADIPNLRRLDFTGNL 154
           C C    V C    +  +P  LP+    L    N++  L A   F  +PNLR+++ + N 
Sbjct: 509 CRCEGTIVDCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNK 568

Query: 155 IEDIEDGTFSKLSLLEELSLAENQLLKLPVLPPKLTLFNAKYNKIKSRGIKANAFKKLNN 214
           I+++ +G F   + ++EL L  NQL                        +    F+ L+ 
Sbjct: 569 IKEVREGAFDGAASVQELMLTGNQL----------------------ETVHGRVFRGLSG 606

Query: 215 LTFLYLDHNALESVPLNL---PESLRVIHLQFNNIASITDDTF 254
           L  L L  N +  V  +      S+R++ L  N I +IT   F
Sbjct: 607 LKTLMLRSNLIGCVSNDTFAGLSSVRLLSLYDNRITTITPGAF 649



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 36/134 (26%), Positives = 59/134 (44%), Gaps = 24/134 (17%)

Query: 97  CVCLSGSVYCEEVDIDAVPP-LPKESAYLYARFNKIKKLTAKDFADIPNLRRLDFTGNLI 155
           C C+   V C    + A+P  +PK+   LY   N +  +  ++ + + +L  +D + N I
Sbjct: 729 CTCMETVVRCSNKGLRALPRGMPKDVTELYLEGNHLTAVP-RELSALRHLTLIDLSNNSI 787

Query: 156 EDIEDGTFSKLSLLEELSLAENQLLKLPVLPPKLTLFNAKYNKIKSRGIKANAFKKLNNL 215
             + + TFS +S L  L L+ N+L  +PV                      +AF  L +L
Sbjct: 788 SMLTNYTFSNMSHLSTLILSYNRLRCIPV----------------------HAFNGLRSL 825

Query: 216 TFLYLDHNALESVP 229
             L L  N + SVP
Sbjct: 826 RVLTLHGNDISSVP 839



 Score = 34.3 bits (77), Expect = 0.14
 Identities = 29/99 (29%), Positives = 47/99 (47%), Gaps = 8/99 (8%)

Query: 171 ELSLAENQLLKLP---VLPPKLTLFNAKYNKIKSRGIKANAFKKLNNLTFLYLDHNALES 227
           EL L  N L  +P        LTL +   N I    +    F  +++L+ L L +N L  
Sbjct: 756 ELYLEGNHLTAVPRELSALRHLTLIDLSNNSISM--LTNYTFSNMSHLSTLILSYNRLRC 813

Query: 228 VPL---NLPESLRVIHLQFNNIASITDDTFCKANDTSYI 263
           +P+   N   SLRV+ L  N+I+S+ + +F      S++
Sbjct: 814 IPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHL 852



 Score = 33.5 bits (75), Expect = 0.23
 Identities = 17/56 (30%), Positives = 30/56 (53%)

Query: 124 LYARFNKIKKLTAKDFADIPNLRRLDFTGNLIEDIEDGTFSKLSLLEELSLAENQL 179
           L   +N+++ +    F  + +LR L   GN I  + +G+F+ L+ L  L+L  N L
Sbjct: 804 LILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPL 859



 Score = 30.0 bits (66), Expect = 2.6
 Identities = 20/66 (30%), Positives = 36/66 (54%), Gaps = 2/66 (3%)

Query: 198 KIKSRGIKANAFKKLNNLTFLYLDHNALESVP--LNLPESLRVIHLQFNNIASITDDTFC 255
           +  ++G++A       ++T LYL+ N L +VP  L+    L +I L  N+I+ +T+ TF 
Sbjct: 737 RCSNKGLRALPRGMPKDVTELYLEGNHLTAVPRELSALRHLTLIDLSNNSISMLTNYTFS 796

Query: 256 KANDTS 261
             +  S
Sbjct: 797 NMSHLS 802


>gi|41349454 proline arginine-rich end leucine-rich repeat protein
           precursor [Homo sapiens]
          Length = 382

 Score = 74.3 bits (181), Expect = 1e-13
 Identities = 58/236 (24%), Positives = 98/236 (41%), Gaps = 25/236 (10%)

Query: 66  PNEKSLQLQKDEAITPLPPKKENDEMPTCLLCVCLSGSVYCEEVDIDAVPPLPKESAYLY 125
           P+E +        + P PP    D    C        ++YC+  ++  VP +P    YLY
Sbjct: 49  PDEPAEPTDLPPPLPPGPPSIFPDCPRECYCPPDFPSALYCDSRNLRKVPVIPPRIHYLY 108

Query: 126 ARFNKIKKLTAKDFADIPNLRRLDFTGNLIEDIEDGTFSKLSLLEELSLAENQLLKLPV- 184
            + N I +L  + F +   LR ++   N I  I+     KL  L  L + +NQL ++P  
Sbjct: 109 LQNNFITELPVESFQNATGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQLEEVPSA 168

Query: 185 -----------------LPP-------KLTLFNAKYNKIKSRGIKANAFKKLNNLTFLYL 220
                            +PP        L L + ++N++     K + F  L NL  L L
Sbjct: 169 LPRNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLNL 228

Query: 221 DHNALESVPLNLPESLRVIHLQFNNIASITDDTFCKANDTSYIRDRIEEIRLEGNP 276
            HN L  +P  +P ++  ++L  N I +I +  F    + ++IR    ++   G P
Sbjct: 229 AHNILRKMPPRVPTAIHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLP 284



 Score = 66.2 bits (160), Expect = 3e-11
 Identities = 77/280 (27%), Positives = 114/280 (40%), Gaps = 62/280 (22%)

Query: 51  YLDGKNIKEKETVIIPNEKSLQLQKDEAITPLPPKKENDEMPTCLLCVCLSGS------- 103
           Y D +N++ K  VI P    L LQ +  IT LP   E+ +  T L  + L  +       
Sbjct: 88  YCDSRNLR-KVPVIPPRIHYLYLQNN-FITELPV--ESFQNATGLRWINLDNNRIRKIDQ 143

Query: 104 -----------VYCEEVDIDAVPP-LPKESAYLYARFNKIKKLTAKDFADIPNLRRLDFT 151
                      +Y E+  ++ VP  LP+    L    N I ++    F+ + NL  LD  
Sbjct: 144 RVLEKLPGLVFLYMEKNQLEEVPSALPRNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQ 203

Query: 152 GNLIED--IEDGTFSKLSLLEELSLAENQLLKLP------------------VLP----- 186
            N + D   +  TF  L  L +L+LA N L K+P                   +P     
Sbjct: 204 HNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRVPTAIHQLYLDSNKIETIPNGYFK 263

Query: 187 --PKLTLFNAKYNKIKSRGIKANAFKKLNNLTFLYLDHNALESVPLNLPESLRVIHLQFN 244
             P L      YNK+  RG+  N+F  ++NL  L+L HN + SVP  +   L  ++L  N
Sbjct: 264 SFPNLAFIRLNYNKLTDRGLPKNSF-NISNLLVLHLSHNRISSVPA-INNRLEHLYLNNN 321

Query: 245 NIASITDDTFCKANDTSYIRD---------RIEEIRLEGN 275
           +I  I     C  ND     D          +  +RL+GN
Sbjct: 322 SIEKINGTQIC-PNDLVAFHDFSSDLENVPHLRYLRLDGN 360


>gi|4506041 proline arginine-rich end leucine-rich repeat protein
           precursor [Homo sapiens]
          Length = 382

 Score = 74.3 bits (181), Expect = 1e-13
 Identities = 58/236 (24%), Positives = 98/236 (41%), Gaps = 25/236 (10%)

Query: 66  PNEKSLQLQKDEAITPLPPKKENDEMPTCLLCVCLSGSVYCEEVDIDAVPPLPKESAYLY 125
           P+E +        + P PP    D    C        ++YC+  ++  VP +P    YLY
Sbjct: 49  PDEPAEPTDLPPPLPPGPPSIFPDCPRECYCPPDFPSALYCDSRNLRKVPVIPPRIHYLY 108

Query: 126 ARFNKIKKLTAKDFADIPNLRRLDFTGNLIEDIEDGTFSKLSLLEELSLAENQLLKLPV- 184
            + N I +L  + F +   LR ++   N I  I+     KL  L  L + +NQL ++P  
Sbjct: 109 LQNNFITELPVESFQNATGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQLEEVPSA 168

Query: 185 -----------------LPP-------KLTLFNAKYNKIKSRGIKANAFKKLNNLTFLYL 220
                            +PP        L L + ++N++     K + F  L NL  L L
Sbjct: 169 LPRNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLNL 228

Query: 221 DHNALESVPLNLPESLRVIHLQFNNIASITDDTFCKANDTSYIRDRIEEIRLEGNP 276
            HN L  +P  +P ++  ++L  N I +I +  F    + ++IR    ++   G P
Sbjct: 229 AHNILRKMPPRVPTAIHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLP 284



 Score = 66.2 bits (160), Expect = 3e-11
 Identities = 77/280 (27%), Positives = 114/280 (40%), Gaps = 62/280 (22%)

Query: 51  YLDGKNIKEKETVIIPNEKSLQLQKDEAITPLPPKKENDEMPTCLLCVCLSGS------- 103
           Y D +N++ K  VI P    L LQ +  IT LP   E+ +  T L  + L  +       
Sbjct: 88  YCDSRNLR-KVPVIPPRIHYLYLQNN-FITELPV--ESFQNATGLRWINLDNNRIRKIDQ 143

Query: 104 -----------VYCEEVDIDAVPP-LPKESAYLYARFNKIKKLTAKDFADIPNLRRLDFT 151
                      +Y E+  ++ VP  LP+    L    N I ++    F+ + NL  LD  
Sbjct: 144 RVLEKLPGLVFLYMEKNQLEEVPSALPRNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQ 203

Query: 152 GNLIED--IEDGTFSKLSLLEELSLAENQLLKLP------------------VLP----- 186
            N + D   +  TF  L  L +L+LA N L K+P                   +P     
Sbjct: 204 HNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRVPTAIHQLYLDSNKIETIPNGYFK 263

Query: 187 --PKLTLFNAKYNKIKSRGIKANAFKKLNNLTFLYLDHNALESVPLNLPESLRVIHLQFN 244
             P L      YNK+  RG+  N+F  ++NL  L+L HN + SVP  +   L  ++L  N
Sbjct: 264 SFPNLAFIRLNYNKLTDRGLPKNSF-NISNLLVLHLSHNRISSVPA-INNRLEHLYLNNN 321

Query: 245 NIASITDDTFCKANDTSYIRD---------RIEEIRLEGN 275
           +I  I     C  ND     D          +  +RL+GN
Sbjct: 322 SIEKINGTQIC-PNDLVAFHDFSSDLENVPHLRYLRLDGN 360


>gi|41350214 asporin [Homo sapiens]
          Length = 380

 Score = 73.2 bits (178), Expect = 3e-13
 Identities = 72/251 (28%), Positives = 108/251 (43%), Gaps = 49/251 (19%)

Query: 89  DEMPTCLL-CVCLSGSVYCEEVDIDAVPP-LPKESAYLYARFNKIKKLTAKDFADIPNLR 146
           D  P C   C C S  V+C ++ + +VP  +P ++  L  + NKIK++   DF  + +L 
Sbjct: 70  DLFPMCPFGCQCYSRVVHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKENDFKGLTSLY 129

Query: 147 RLDFTGNLIEDIEDGTFSKLSLLEELSLAENQLLKLPV-LPPKLTLFNAKYNKIKSRGIK 205
            L    N +  I    F     L  L L+ NQL ++P+ LP  L       NK+K   I+
Sbjct: 130 GLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLNLPKSLAELRIHENKVKK--IQ 187

Query: 206 ANAFKKLNNLTFLY-----LDHNALE--------------------SVPLNLPESLRVIH 240
            + FK +N L  L      LD+N +E                    SVP  LP +L  +H
Sbjct: 188 KDTFKGMNALHVLEMSANPLDNNGIEPGAFEGVTVFHIRIAEAKLTSVPKGLPPTLLELH 247

Query: 241 LQFNNIASITDDTFCKAND-------TSYIRD----------RIEEIRLEGNPIVLGKHP 283
           L +N I+++  + F +  +        + I D          R+ EI LE N   L K P
Sbjct: 248 LDYNKISTVELEDFKRYKELQRLGLGNNKITDIENGSLANIPRVREIHLENNK--LKKIP 305

Query: 284 NSFICLKRLPI 294
           +    LK L I
Sbjct: 306 SGLPELKYLQI 316


>gi|226342935 podocan-like 1 isoform 3 [Homo sapiens]
          Length = 421

 Score = 72.0 bits (175), Expect = 6e-13
 Identities = 56/212 (26%), Positives = 100/212 (47%), Gaps = 20/212 (9%)

Query: 77  EAITPLPPKKENDEMPTC-LLCVCLS-GSVYCEEVDIDAVPP-LPKESAYLYARFNKIKK 133
           E++ PLP          C L C C    +V C+ +D+   P  + + + +L  + N++++
Sbjct: 35  ESLQPLPR--------ACPLRCSCPRVDTVDCDGLDLRVFPDNITRAAQHLSLQNNQLQE 86

Query: 134 LTAKDFADIPNLRRLDFTGNLI--EDIEDGTFSKLSLLEELSLAENQLLKLPVLP----- 186
           L   + + +  LR L+   NLI  E + D  F  L+ L+ L +A N+   +  +P     
Sbjct: 87  LPYNELSRLSGLRTLNLHNNLISSEGLPDEAFESLTQLQHLCVAHNKNNLISKVPRGALS 146

Query: 187 --PKLTLFNAKYNKIKSRGIKANAFKKLNNLTFLYLDHNALESVPLNLPESLRVIHLQFN 244
              +L     ++N++   G+ A  F KL++L +L L HN L +VP  LP +L ++HL  N
Sbjct: 147 RQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAILHLGRN 206

Query: 245 NIASITDDTFCKANDTSYIRDRIEEIRLEGNP 276
            I  +       A    Y+  +  ++   G P
Sbjct: 207 RIRQVEAARLHGARGLRYLLLQHNQLGSSGLP 238



 Score = 48.9 bits (115), Expect = 5e-06
 Identities = 50/191 (26%), Positives = 76/191 (39%), Gaps = 34/191 (17%)

Query: 117 LPKESAYLYARFNKIKKLTAKDFADIPNLRRLDFTGNLI--EDIEDGTFSKLSLLEELSL 174
           LP+  A L+   N+I+++ A        LR L    N +    +  G    L  L  L L
Sbjct: 194 LPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHL 253

Query: 175 AENQLLKLP----------VLP---------------PKLTLFNAKYNKIKSRGIKANAF 209
             N L ++P          VLP               P LT  N  YN++ S  +   AF
Sbjct: 254 YGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRAF 313

Query: 210 KKLNNLTFLYLDHNALESVPLNLPESLRVIHLQFNNIASITDDTFCKANDTSYIRDRIEE 269
           ++L  L  L L  N L  +P+ LP  LR + LQ N +  +  +            D++ E
Sbjct: 314 RRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAGL-------DQLRE 366

Query: 270 IRLEGNPIVLG 280
           + L  N + +G
Sbjct: 367 LSLAHNRLRVG 377



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 38/119 (31%), Positives = 54/119 (45%), Gaps = 6/119 (5%)

Query: 111 IDAVPP-LPKESAYLYARFNKIKKLTAKDFADIPNLRRLDFTGNLIED--IEDGTFSKLS 167
           +D VPP LP+    L    N +  L A+D    P L  L+   N +    +    F +L 
Sbjct: 258 LDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRAFRRLR 317

Query: 168 LLEELSLAENQLLKLPV-LPPKLTLFNAKYNKIKSRGIKANAFKKLNNLTFLYLDHNAL 225
            L  L LA NQL +LP+ LP  L     + N++  R ++      L+ L  L L HN L
Sbjct: 318 ALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQL--RMLEPEPLAGLDQLRELSLAHNRL 374


>gi|5901992 keratocan [Homo sapiens]
          Length = 352

 Score = 72.0 bits (175), Expect = 6e-13
 Identities = 54/201 (26%), Positives = 90/201 (44%), Gaps = 27/201 (13%)

Query: 103 SVYCEEVDIDAVPPLPKESAYLYARFNKIKKLTAKDFADIPNLRRLDFTGNLIED--IED 160
           ++YCE   +  +P +P    YLY + N I+ +  K F +   LR ++   N I +  IE 
Sbjct: 55  ALYCENRGLKEIPAIPSRIWYLYLQNNLIETIPEKPFENATQLRWINLNKNKITNYGIEK 114

Query: 161 GTFSKLSLLEELSLAENQLLKLPVLPPK-------------------------LTLFNAK 195
           G  S+L  L  L L +N+L ++P   P+                         LTL + +
Sbjct: 115 GALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQGTFSNLENLTLLDLQ 174

Query: 196 YNKIKSRGIKANAFKKLNNLTFLYLDHNALESVPLNLPESLRVIHLQFNNIASITDDTFC 255
            NK+     + + FK L NL  L +  NAL ++P  LP +   + L  N+I  I ++ F 
Sbjct: 175 NNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFLDNNSIEGIPENYFN 234

Query: 256 KANDTSYIRDRIEEIRLEGNP 276
                +++R    ++  EG P
Sbjct: 235 VIPKVAFLRLNHNKLSDEGLP 255



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 37/141 (26%), Positives = 65/141 (46%), Gaps = 18/141 (12%)

Query: 115 PPLPKESAYLYARFNKIKKLTAKDFADIPNLRRLDFTGNLIEDIEDGTFSK---LSLLEE 171
           P LP  +  L+   N I+ +    F  IP +  L    N + D  +G  S+   +S + +
Sbjct: 209 PRLPANTMQLFLDNNSIEGIPENYFNVIPKVAFLRLNHNKLSD--EGLPSRGFDVSSILD 266

Query: 172 LSLAENQLLKLPVLPPKLTLFNAKYNKIKSRGI------------KANAFKKLNNLTFLY 219
           L L+ NQL K+P +   L   +  +NKIKS  +            + ++F    +L +L 
Sbjct: 267 LQLSHNQLTKVPRISAHLQHLHLDHNKIKSVNVSVICPSPSMLPAERDSFSYGPHLRYLR 326

Query: 220 LDHNALE-SVPLNLPESLRVI 239
           LD N ++  +P+ L    R++
Sbjct: 327 LDGNEIKPPIPMALMTCFRLL 347


>gi|45505137 podocan [Homo sapiens]
          Length = 661

 Score = 70.9 bits (172), Expect = 1e-12
 Identities = 62/204 (30%), Positives = 97/204 (47%), Gaps = 35/204 (17%)

Query: 117 LPKESAYLYARFNKIKKLTAKDFADIPNLRRLDFTGNLIED--IEDGTFSKLSLLEELSL 174
           LP     L+ + NK++K+    F+++ +LR L    N + D  +++ TF KLS LE L L
Sbjct: 284 LPPALYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDL 343

Query: 175 AENQLLKLPV-LPPKLTLFNAKYNKIKS------------------------RGIKANAF 209
           + N L ++P  LP  L L + + N I+S                        +GI   AF
Sbjct: 344 SSNNLSRVPAGLPRSLVLLHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAF 403

Query: 210 KKLNNLTFLYLDHNALESVPLNLPESLRVIHLQFNNIASITDDTFCKANDTSYIRDRIEE 269
           + L  L  ++L +NALE VP  LP  +R + +  N I  I  + F     T+Y    +EE
Sbjct: 404 QGLKRLHTVHLYNNALERVPSGLPRRVRTLMILHNQITGIGREDFA----TTYF---LEE 456

Query: 270 IRLEGNPIVLGK-HPNSFICLKRL 292
           + L  N I   + H ++F  L+ L
Sbjct: 457 LNLSYNRITSPQVHRDAFRKLRLL 480



 Score = 63.5 bits (153), Expect = 2e-10
 Identities = 55/191 (28%), Positives = 81/191 (42%), Gaps = 33/191 (17%)

Query: 129 NKIKKLTAKDFADIPNLRRLDFTGNLIED--IEDGTFSKLSLLEELSLAENQLLKLPV-L 185
           N + K+    F   PNLR +    N + D  + D  F+  S +E L L+ N L  +P  L
Sbjct: 225 NYLTKIYGLTFGQKPNLRSVYLHNNKLADAGLPDNMFNGSSNVEVLILSSNFLRHVPKHL 284

Query: 186 PPKLTLFNAKYNKIKS------------------------RGIKANAFKKLNNLTFLYLD 221
           PP L   + K NK++                          G+    F KL++L +L L 
Sbjct: 285 PPALYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLS 344

Query: 222 HNALESVPLNLPESLRVIHLQFNNIASITDDTFCKANDTSYIRDRIEEIRLEGNPIVLGK 281
            N L  VP  LP SL ++HL+ N I S+  +         Y+     ++R +      G 
Sbjct: 345 SNNLSRVPAGLPRSLVLLHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLREQ------GI 398

Query: 282 HPNSFICLKRL 292
           HP +F  LKRL
Sbjct: 399 HPLAFQGLKRL 409



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 48/172 (27%), Positives = 75/172 (43%), Gaps = 28/172 (16%)

Query: 111 IDAVPP-LPKESAYLYARFNKIKKLTAKDFADIPNLRRLDFTGNLIED--IEDGTFSKLS 167
           ++ VP  LP+    L    N+I  +  +DFA    L  L+ + N I    +    F KL 
Sbjct: 419 LERVPSGLPRRVRTLMILHNQITGIGREDFATTYFLEELNLSYNRITSPQVHRDAFRKLR 478

Query: 168 LLEELSLAENQLLKLPV-LPPKLTLFNAKYN------------------------KIKSR 202
           LL  L L+ N+L  LP  LP  + +   K N                        +++SR
Sbjct: 479 LLRSLDLSGNRLHTLPPGLPRNVHVLKVKRNELAALARGALVGMAQLRELYLTSNRLRSR 538

Query: 203 GIKANAFKKLNNLTFLYLDHNALESVPLNLPESLRVIHLQFNNIASITDDTF 254
            +   A+  L +L  L +  N L  +P  LPESL  ++LQ N I+++  + F
Sbjct: 539 ALGPRAWVDLAHLQLLDIAGNQLTEIPEGLPESLEYLYLQNNKISAVPANAF 590



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 32/89 (35%), Positives = 45/89 (50%), Gaps = 8/89 (8%)

Query: 172 LSLAENQLLKLPVLPPKLT------LFNAKYNKIKSRGIKANAFKKLNNLTFLYLDHNAL 225
           LSL  NQL K  + P +L+        N + N++ SRG+   AF+ L NL +LYL +N L
Sbjct: 149 LSLQNNQLEK--IYPEELSRLHRLETLNLQNNRLTSRGLPEKAFEHLTNLNYLYLANNKL 206

Query: 226 ESVPLNLPESLRVIHLQFNNIASITDDTF 254
              P  LP +L  +    N +  I   TF
Sbjct: 207 TLAPRFLPNALISVDFAANYLTKIYGLTF 235



 Score = 45.1 bits (105), Expect = 8e-05
 Identities = 40/160 (25%), Positives = 65/160 (40%), Gaps = 27/160 (16%)

Query: 117 LPKESAYLYARFNKIKKLTAKDFADIPNLRRLDFTGNLIED--IEDGTFSKLSLLEELSL 174
           LP+    L+   N I+ + A     I +L  L    N + +  I    F  L  L  + L
Sbjct: 355 LPRSLVLLHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAFQGLKRLHTVHL 414

Query: 175 AENQLLKLPVLPPK-------------------------LTLFNAKYNKIKSRGIKANAF 209
             N L ++P   P+                         L   N  YN+I S  +  +AF
Sbjct: 415 YNNALERVPSGLPRRVRTLMILHNQITGIGREDFATTYFLEELNLSYNRITSPQVHRDAF 474

Query: 210 KKLNNLTFLYLDHNALESVPLNLPESLRVIHLQFNNIASI 249
           +KL  L  L L  N L ++P  LP ++ V+ ++ N +A++
Sbjct: 475 RKLRLLRSLDLSGNRLHTLPPGLPRNVHVLKVKRNELAAL 514



 Score = 34.7 bits (78), Expect = 0.10
 Identities = 21/63 (33%), Positives = 30/63 (47%), Gaps = 2/63 (3%)

Query: 117 LPKESAYLYARFNKIKKLTAKDFADIPNLRR--LDFTGNLIEDIEDGTFSKLSLLEELSL 174
           LP+   YLY + NKI  + A  F   PNL+   L F    +  + D  F +L  L+ L +
Sbjct: 568 LPESLEYLYLQNNKISAVPANAFDSTPNLKGIFLRFNKLAVGSVVDSAFRRLKHLQVLDI 627

Query: 175 AEN 177
             N
Sbjct: 628 EGN 630


>gi|86990456 leucine rich repeat transmembrane neuronal 1 [Homo
           sapiens]
          Length = 522

 Score = 70.5 bits (171), Expect = 2e-12
 Identities = 51/190 (26%), Positives = 92/190 (48%), Gaps = 16/190 (8%)

Query: 96  LCVCLSGSVYCEEVDIDAVPPLPKESAYLYARFNKIKKLTAKDFADIPNLRRLDFTGNLI 155
           LC C    +YCE +++   P        L  R+N + +L A  F  +  L  L    N I
Sbjct: 42  LCRCEGRLLYCEALNLTEAPHNLSGLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHI 101

Query: 156 EDIEDGTFSKLSLLEELSLAENQLLKLPVLP----PKLTLFNAKYNKIKSRGIKANAFKK 211
             ++   F KL  ++EL+L+ NQ+ +LP       P L   +  YNK+++  +  + F  
Sbjct: 102 CSVQGDAFQKLRRVKELTLSSNQITQLPNTTFRPMPNLRSVDLSYNKLQA--LAPDLFHG 159

Query: 212 LNNLTFLYLDHNALESVPLNLPE---SLRVIHLQFNNIASITDDTFCKANDTSYIRDRIE 268
           L  LT L++  NA++ VP+ + +   SL+ + + +N + S+  ++F           ++ 
Sbjct: 160 LRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKSLARNSFAGL-------FKLT 212

Query: 269 EIRLEGNPIV 278
           E+ LE N +V
Sbjct: 213 ELHLEHNDLV 222



 Score = 29.3 bits (64), Expect = 4.4
 Identities = 14/36 (38%), Positives = 21/36 (58%)

Query: 144 NLRRLDFTGNLIEDIEDGTFSKLSLLEELSLAENQL 179
           NL ++D +GN IE +E   F  +  L+ L L  N+L
Sbjct: 257 NLEKMDLSGNEIEYMEPHVFETVPHLQSLQLDSNRL 292


>gi|71040111 fibromodulin precursor [Homo sapiens]
          Length = 376

 Score = 70.5 bits (171), Expect = 2e-12
 Identities = 53/188 (28%), Positives = 85/188 (45%), Gaps = 28/188 (14%)

Query: 103 SVYCEEVDIDAVPPLPKESAYLYARFNKIKKLTAKDFADIPNLRRLDFTGNLIEDIEDG- 161
           ++YC+  ++  +P +P    Y+Y + N+I  +    F +   L  +   GN I   + G 
Sbjct: 89  AMYCDNRNLKYLPFVPSRMKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGR 148

Query: 162 -TFSKLSLLEELSLAENQLLKLP-VLPPKLTLFNAKYNKIKSRGIKANAFKKLNNLTFLY 219
             FSKL  LE L L  N L ++P  LP  L   +  +N+I    +  NA + L NLT LY
Sbjct: 149 KVFSKLRHLERLYLDHNNLTRMPGPLPRSLRELHLDHNQISR--VPNNALEGLENLTALY 206

Query: 220 LDHNALESV-----------------------PLNLPESLRVIHLQFNNIASITDDTFCK 256
           L HN ++ V                       P  LP +L  ++++ NN+ ++ D  F  
Sbjct: 207 LQHNEIQEVGSSMRGLRSLILLDLSYNHLRKVPDGLPSALEQLYMEHNNVYTVPDSYFRG 266

Query: 257 ANDTSYIR 264
           A    Y+R
Sbjct: 267 APKLLYVR 274



 Score = 36.2 bits (82), Expect = 0.036
 Identities = 36/133 (27%), Positives = 57/133 (42%), Gaps = 9/133 (6%)

Query: 117 LPKESAYLYARFNKIKKLTAKDFADIPNLRRLDFTGNLIED--IEDGTFSKLSLLEELSL 174
           LP     LY   N +  +    F   P L  +  + N + +  +   TF+  SLLE L L
Sbjct: 242 LPSALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNNGLASNTFNSSSLLE-LDL 300

Query: 175 AENQLLKLPVLPPKLTLFNAKYNKIKSRGIKANA----FKKLNNLTFLYLDHNALE--SV 228
           + NQL K+P +   L     + N+I    I +          + L  L LD N ++  ++
Sbjct: 301 SYNQLQKIPPVNTNLENLYLQGNRINEFSISSFCTVVDVVNFSKLQVLRLDGNEIKRSAM 360

Query: 229 PLNLPESLRVIHL 241
           P + P  LR+  L
Sbjct: 361 PADAPLCLRLASL 373


>gi|156139147 leucine rich repeat transmembrane neuronal 4 isoform b
           [Homo sapiens]
          Length = 518

 Score = 67.4 bits (163), Expect = 1e-11
 Identities = 59/195 (30%), Positives = 89/195 (45%), Gaps = 18/195 (9%)

Query: 105 YCEEVDIDAVPPLPKESAYLYARFNKIKKLTAKDFADIPNLRRLDFTGNLIEDIEDGTFS 164
           Y   VD DA   + +    + +  NKI  L  K F  +PNLR LD + N ++ ++   F 
Sbjct: 96  YISSVDEDAFQGIRRLKELILSS-NKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFK 154

Query: 165 KLSLLEELSLAENQLLKLPVLP----PKLTLFNAKYNKIKSRGIKANAFKKLNNLTFLYL 220
            L  L  L L  N L  +P+        L   +  YN+++S  +  NAF  L  L  L+L
Sbjct: 155 GLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRS--LSRNAFAGLLKLKELHL 212

Query: 221 DHNALESVPL-NLPE--SLRVIHLQFNNIASITDDTFCKANDTSYIRDRIEEIRLEGNPI 277
           +HN    +   + P   +LR I+LQ+N I SI       +   ++    +  + L GN I
Sbjct: 213 EHNQFSKINFAHFPRLFNLRSIYLQWNRIRSI-------SQGLTWTWSSLHNLDLSGNDI 265

Query: 278 VLGKHPNSFICLKRL 292
             G  P +F CL  L
Sbjct: 266 -QGIEPGTFKCLPNL 279



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 38/131 (29%), Positives = 55/131 (41%), Gaps = 26/131 (19%)

Query: 124 LYARFNKIKKLTAKDFADIPNLRRLDFTGNLIEDIEDGTFSKLSLLEELSLAENQLLKLP 183
           L+ R N +K +  + F D  NL  LD   N +  +    F+ L  L+EL L  NQ  K+ 
Sbjct: 162 LHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKIN 221

Query: 184 VLP-PKLTLFNAKY---NKIKS----------------------RGIKANAFKKLNNLTF 217
               P+L    + Y   N+I+S                      +GI+   FK L NL  
Sbjct: 222 FAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQK 281

Query: 218 LYLDHNALESV 228
           L LD N L ++
Sbjct: 282 LNLDSNKLTNI 292



 Score = 36.2 bits (82), Expect = 0.036
 Identities = 22/63 (34%), Positives = 35/63 (55%), Gaps = 5/63 (7%)

Query: 195 KYNKIKSRGIKANAFKKLNNLTFLYLDHNALESVPLNLPESLRVIH---LQFNNIASITD 251
           ++N I+   +K+N F  LN L +LYLDHN + SV  +  + +R +    L  N I  + +
Sbjct: 69  RFNSIQK--LKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHN 126

Query: 252 DTF 254
            TF
Sbjct: 127 KTF 129


>gi|197927168 leucine rich repeat transmembrane neuronal 4 isoform a
           [Homo sapiens]
          Length = 590

 Score = 67.4 bits (163), Expect = 1e-11
 Identities = 59/195 (30%), Positives = 89/195 (45%), Gaps = 18/195 (9%)

Query: 105 YCEEVDIDAVPPLPKESAYLYARFNKIKKLTAKDFADIPNLRRLDFTGNLIEDIEDGTFS 164
           Y   VD DA   + +    + +  NKI  L  K F  +PNLR LD + N ++ ++   F 
Sbjct: 96  YISSVDEDAFQGIRRLKELILSS-NKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFK 154

Query: 165 KLSLLEELSLAENQLLKLPVLP----PKLTLFNAKYNKIKSRGIKANAFKKLNNLTFLYL 220
            L  L  L L  N L  +P+        L   +  YN+++S  +  NAF  L  L  L+L
Sbjct: 155 GLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRS--LSRNAFAGLLKLKELHL 212

Query: 221 DHNALESVPL-NLPE--SLRVIHLQFNNIASITDDTFCKANDTSYIRDRIEEIRLEGNPI 277
           +HN    +   + P   +LR I+LQ+N I SI       +   ++    +  + L GN I
Sbjct: 213 EHNQFSKINFAHFPRLFNLRSIYLQWNRIRSI-------SQGLTWTWSSLHNLDLSGNDI 265

Query: 278 VLGKHPNSFICLKRL 292
             G  P +F CL  L
Sbjct: 266 -QGIEPGTFKCLPNL 279



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 38/131 (29%), Positives = 55/131 (41%), Gaps = 26/131 (19%)

Query: 124 LYARFNKIKKLTAKDFADIPNLRRLDFTGNLIEDIEDGTFSKLSLLEELSLAENQLLKLP 183
           L+ R N +K +  + F D  NL  LD   N +  +    F+ L  L+EL L  NQ  K+ 
Sbjct: 162 LHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKIN 221

Query: 184 VLP-PKLTLFNAKY---NKIKS----------------------RGIKANAFKKLNNLTF 217
               P+L    + Y   N+I+S                      +GI+   FK L NL  
Sbjct: 222 FAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQK 281

Query: 218 LYLDHNALESV 228
           L LD N L ++
Sbjct: 282 LNLDSNKLTNI 292



 Score = 36.2 bits (82), Expect = 0.036
 Identities = 22/63 (34%), Positives = 35/63 (55%), Gaps = 5/63 (7%)

Query: 195 KYNKIKSRGIKANAFKKLNNLTFLYLDHNALESVPLNLPESLRVIH---LQFNNIASITD 251
           ++N I+   +K+N F  LN L +LYLDHN + SV  +  + +R +    L  N I  + +
Sbjct: 69  RFNSIQK--LKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHN 126

Query: 252 DTF 254
            TF
Sbjct: 127 KTF 129


>gi|188528675 slit homolog 1 [Homo sapiens]
          Length = 1534

 Score = 65.1 bits (157), Expect = 7e-11
 Identities = 52/167 (31%), Positives = 75/167 (44%), Gaps = 10/167 (5%)

Query: 96  LCVCLSGSVYCEEVDIDAVPP-LPKESAYLYARFNKIKKLTAKDFADIPNLRRLDFTGNL 154
           LC C   +V C    + A+P  +P+ +  L    N I ++   DFA +  LR L    N 
Sbjct: 37  LCTCTGTTVDCHGTGLQAIPKNIPRNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQ 96

Query: 155 IEDIEDGTFSKLSLLEELSLAENQLLKLPVL----PPKLTLFNAKYNKIKSRGIKANAFK 210
           I  +E G F  +  LE L L  NQL  LP L       L+  +   N I++  I   AF+
Sbjct: 97  IGAVERGAFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQA--IPRKAFR 154

Query: 211 KLNNLTFLYLDHNALESVPLNLPESLR---VIHLQFNNIASITDDTF 254
              +L  L LD N +  +      +LR   V+ L  NNI +I   +F
Sbjct: 155 GATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSF 201



 Score = 65.1 bits (157), Expect = 7e-11
 Identities = 52/164 (31%), Positives = 72/164 (43%), Gaps = 11/164 (6%)

Query: 87  ENDEMPTCLL--------CVCLSGSVYCEEVDIDAVPP-LPKESAYLYARFNKIKKLTAK 137
           E   +PTC L        C C +G V C    + A+P  LP+    +    N IK +   
Sbjct: 268 EAGRVPTCTLSSGSCPAMCTCSNGIVDCRGKGLTAIPANLPETMTEIRLELNGIKSIPPG 327

Query: 138 DFADIPNLRRLDFTGNLIEDIEDGTFSKLSLLEELSLAENQLLKLP--VLPPKLTLFNAK 195
            F+    LRR+D + N I +I    F  L  L  L L  N++  LP  V     TL    
Sbjct: 328 AFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLL 387

Query: 196 YNKIKSRGIKANAFKKLNNLTFLYLDHNALESVPLNLPESLRVI 239
            N  K   I+ +AF+ L NL+ L L  N ++S+      SLR I
Sbjct: 388 LNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAI 431



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 46/200 (23%), Positives = 82/200 (41%), Gaps = 37/200 (18%)

Query: 60  KETVIIPNEKSLQLQKDEAITPLPPKKENDEMPTCLLCVCLSGSVYCEEVDIDAVPP-LP 118
           KE   IP  +  QL  +     + P K          C C +  V C  + +  +P  +P
Sbjct: 490 KEQYFIPGTEDYQLNSECNSDVVCPHK----------CRCEANVVECSSLKLTKIPERIP 539

Query: 119 KESAYLYARFNKIKKLTAKD-FADIPNLRRLDFTGNLIEDIEDGTFSKLSLLEELSLAEN 177
           + +A L    N+I  L A   F  + +L++++ + N + +IEDG F   + + EL L  N
Sbjct: 540 QSTAELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTAN 599

Query: 178 QLLKLPVLPPKLTLFNAKYNKIKSRGIKANAFKKLNNLTFLYLDHNALESV---PLNLPE 234
           QL                        I++  F+ L+ L  L L +N +  +         
Sbjct: 600 QL----------------------ESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLR 637

Query: 235 SLRVIHLQFNNIASITDDTF 254
           ++R++ L  N I +++   F
Sbjct: 638 NVRLLSLYDNQITTVSPGAF 657



 Score = 36.2 bits (82), Expect = 0.036
 Identities = 18/52 (34%), Positives = 27/52 (51%)

Query: 129 NKIKKLTAKDFADIPNLRRLDFTGNLIEDIEDGTFSKLSLLEELSLAENQLL 180
           NKI  +    F D+ NL  L    N I+ +  GTF+ L  ++ L LA+N  +
Sbjct: 391 NKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFI 442



 Score = 36.2 bits (82), Expect = 0.036
 Identities = 23/78 (29%), Positives = 41/78 (52%), Gaps = 5/78 (6%)

Query: 189 LTLFNAKYNKIKSRGIKANAFKKLNNLTFLYLDHNALESVP---LNLPESLRVIHLQFNN 245
           L L +   NKI S  +  ++F  ++ LT L L +NAL+ +P        SLR++ L  N+
Sbjct: 786 LQLVDLSNNKISS--LSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGND 843

Query: 246 IASITDDTFCKANDTSYI 263
           I+++ +  F      S++
Sbjct: 844 ISTLQEGIFADVTSLSHL 861



 Score = 29.6 bits (65), Expect = 3.4
 Identities = 13/30 (43%), Positives = 18/30 (60%)

Query: 225 LESVPLNLPESLRVIHLQFNNIASITDDTF 254
           L ++P NLPE++  I L+ N I SI    F
Sbjct: 300 LTAIPANLPETMTEIRLELNGIKSIPPGAF 329



 Score = 28.9 bits (63), Expect = 5.7
 Identities = 17/54 (31%), Positives = 23/54 (42%)

Query: 124 LYARFNKIKKLTAKDFADIPNLRRLDFTGNLIEDIEDGTFSKLSLLEELSLAEN 177
           L  R N+I  +    F  + N+R L    N I  +  G F  L  L  L+L  N
Sbjct: 618 LMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLAN 671



 Score = 28.5 bits (62), Expect = 7.5
 Identities = 16/43 (37%), Positives = 27/43 (62%), Gaps = 2/43 (4%)

Query: 214 NLTFLYLDHNALESVP--LNLPESLRVIHLQFNNIASITDDTF 254
           N+T LYLD N    VP  L+  + L+++ L  N I+S+++ +F
Sbjct: 762 NVTELYLDGNQFTLVPGQLSTFKYLQLVDLSNNKISSLSNSSF 804


>gi|153251229 chondroadherin precursor [Homo sapiens]
          Length = 359

 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 59/212 (27%), Positives = 92/212 (43%), Gaps = 38/212 (17%)

Query: 97  CVCLSG--SVYCEEVDIDAVPPLPKESAYLYARFNKIKKLTAKDFADIPNLRRLD----- 149
           C C S    V C++V +  +P + +++  L  + N    L A  F  +PNL  L      
Sbjct: 27  CHCHSDLQHVICDKVGLQKIPKVSEKTKLLNLQRNNFPVLAANSFRAMPNLVSLHLQHCQ 86

Query: 150 --------FTG-----------NLIEDIEDGTFSKLSLLEELSLAENQLLKLP--VLPPK 188
                   F G           N I  +  G F  L+ L  L L  N++ +LP  +L P 
Sbjct: 87  IREVAAGAFRGLKQLIYLYLSHNDIRVLRAGAFDDLTELTYLYLDHNKVTELPRGLLSPL 146

Query: 189 LTLFNAKYNKIKSRGIKANAFKKLNNLTFLYLDHNALESV---PLNLPESLRVIHLQFNN 245
           + LF  + N  K R ++A AF+   +L +LYL  NAL S+    L+  E+L   H+  N 
Sbjct: 147 VNLFILQLNNNKIRELRAGAFQGAKDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQ 206

Query: 246 IASITDDTFCKANDTSYIRDRIEEIRLEGNPI 277
           ++S       K          +EE++L  NP+
Sbjct: 207 LSSYPSAALSKLR-------VVEELKLSHNPL 231



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 36/135 (26%), Positives = 54/135 (40%), Gaps = 14/135 (10%)

Query: 119 KESAYLYARFNKIKKLTAKDFADIPNLRRLDFTGNLIEDIEDGTFSKLSLLEELSLAENQ 178
           K+  +LY   N +  L      D+ NL +     N +        SKL ++EEL L+ N 
Sbjct: 171 KDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHNP 230

Query: 179 LLKLP--------VLPPKLTLFNAKYNKIKSRGIKANAFKKLNNLTFLYLDHNALESVPL 230
           L  +P             L L N    K         AF  +  L  ++L++N L  +P 
Sbjct: 231 LKSIPDNAFQSFGRYLETLWLDNTNLEKFSD-----GAFLGVTTLKHVHLENNRLNQLPS 285

Query: 231 NLP-ESLRVIHLQFN 244
           N P +SL  + L  N
Sbjct: 286 NFPFDSLETLALTNN 300


>gi|4759146 slit homolog 2 [Homo sapiens]
          Length = 1529

 Score = 61.6 bits (148), Expect = 8e-10
 Identities = 51/166 (30%), Positives = 75/166 (45%), Gaps = 10/166 (6%)

Query: 97  CVCLSGSVYCEEVDIDAVPP-LPKESAYLYARFNKIKKLTAKDFADIPNLRRLDFTGNLI 155
           C C   +V C  + + +VP  +P+ +  L    N I ++T  DFA + +LR L    N I
Sbjct: 32  CSCSGSTVDCHGLALRSVPRNIPRNTERLDLNGNNITRITKTDFAGLRHLRVLQLMENKI 91

Query: 156 EDIEDGTFSKLSLLEELSLAENQLLKLPVL----PPKLTLFNAKYNKIKSRGIKANAFKK 211
             IE G F  L  LE L L  N L   P L      KL   +   N+I++  I   AF+ 
Sbjct: 92  STIERGAFQDLKELERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQA--IPRKAFRG 149

Query: 212 LNNLTFLYLDHN---ALESVPLNLPESLRVIHLQFNNIASITDDTF 254
             ++  L LD+N    +E         L V+ L  NNI  ++  +F
Sbjct: 150 AVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNITRLSVASF 195



 Score = 55.5 bits (132), Expect = 6e-08
 Identities = 44/150 (29%), Positives = 68/150 (45%), Gaps = 11/150 (7%)

Query: 97  CVCLSGSVYCEEVDIDAVPP-LPKESAYLYARFNKIKKLTAKDFADIPNLRRLDFTGNLI 155
           C C +  V C    +  +P  LP+    +    N IK +    F+    LRR+D + N I
Sbjct: 277 CTCSNNIVDCRGKGLTEIPTNLPETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQI 336

Query: 156 EDIEDGTFSKLSLLEELSLAENQLLKLP------VLPPKLTLFNAKYNKIKSRGIKANAF 209
            ++    F  L  L  L L  N++ +LP      +   +L L NA  NKI    ++ +AF
Sbjct: 337 SELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNA--NKINC--LRVDAF 392

Query: 210 KKLNNLTFLYLDHNALESVPLNLPESLRVI 239
           + L+NL  L L  N L+++       LR I
Sbjct: 393 QDLHNLNLLSLYDNKLQTIAKGTFSPLRAI 422



 Score = 48.5 bits (114), Expect = 7e-06
 Identities = 42/163 (25%), Positives = 69/163 (42%), Gaps = 27/163 (16%)

Query: 97  CVCLSGSVYCEEVDIDAVPP-LPKESAYLYARFNKIKKLTAKD-FADIPNLRRLDFTGNL 154
           C C   +V C    ++ +P  +P+ +A L    N+   L A   F  +P LR+++F+ N 
Sbjct: 510 CRCEGTTVDCSNQKLNKIPEHIPQYTAELRLNNNEFTVLEATGIFKKLPQLRKINFSNNK 569

Query: 155 IEDIEDGTFSKLSLLEELSLAENQLLKLPVLPPKLTLFNAKYNKIKSRGIKANAFKKLNN 214
           I DIE+G F   S + E+ L  N+L                        ++   FK L +
Sbjct: 570 ITDIEEGAFEGASGVNEILLTSNRL----------------------ENVQHKMFKGLES 607

Query: 215 LTFLYLDHNALESVPLNL---PESLRVIHLQFNNIASITDDTF 254
           L  L L  N +  V  +      S+R++ L  N I ++    F
Sbjct: 608 LKTLMLRSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAF 650



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 36/137 (26%), Positives = 62/137 (45%), Gaps = 14/137 (10%)

Query: 97  CVCLSGSVYCEEVDIDAVPP-LPKESAYLYARFNKIKKLTAKDFADIPNLRRLDFTGNLI 155
           C CL   V C    +  +P  +P++   LY   N+   L  K+ ++  +L  +D + N I
Sbjct: 731 CTCLDTVVRCSNKGLKVLPKGIPRDVTELYLDGNQFT-LVPKELSNYKHLTLIDLSNNRI 789

Query: 156 EDIEDGTFSKLSLLEELSLAENQLLKLPVLPPK-------LTLFNAKYNKIKSRGIKANA 208
             + + +FS ++ L  L L+ N   +L  +PP+       L L +   N I    +   A
Sbjct: 790 STLSNQSFSNMTQLLTLILSYN---RLRCIPPRTFDGLKSLRLLSLHGNDISV--VPEGA 844

Query: 209 FKKLNNLTFLYLDHNAL 225
           F  L+ L+ L +  N L
Sbjct: 845 FNDLSALSHLAIGANPL 861



 Score = 37.0 bits (84), Expect = 0.021
 Identities = 19/52 (36%), Positives = 27/52 (51%)

Query: 129 NKIKKLTAKDFADIPNLRRLDFTGNLIEDIEDGTFSKLSLLEELSLAENQLL 180
           NKI  L    F D+ NL  L    N ++ I  GTFS L  ++ + LA+N  +
Sbjct: 382 NKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQNPFI 433


>gi|76880480 hypothetical protein LOC9865 [Homo sapiens]
          Length = 811

 Score = 60.8 bits (146), Expect = 1e-09
 Identities = 60/198 (30%), Positives = 90/198 (45%), Gaps = 13/198 (6%)

Query: 81  PLPPKKENDEMPTCLLCVCLSGSVYCEEVDIDAVPPLPKESAYLYARFNKIKKLTAKDFA 140
           P+ P++ + + P  LLC      V  +   +    P P +        N I  +TA DF 
Sbjct: 25  PVCPERCDCQHPQHLLCTNRGLRVVPKTSSL----PSPHDVLTYSLGGNFITNITAFDFH 80

Query: 141 DIPNLRRLDFTGNLIEDIEDGTFSKLSLLEELSLAEN--QLLKLPVLPP--KLTLFNAKY 196
            +  LRRLD   N I  +   TF KLS LEEL L  N  Q L    L P  KL +  A  
Sbjct: 81  RLGQLRRLDLQYNQIRSLHPKTFEKLSRLEELYLGNNLLQALAPGTLAPLRKLRILYANG 140

Query: 197 NKIKSRGIKANAFKKLNNLTFLYLDHNALESVP--LNLP-ESLRVIHLQFNNIASITDDT 253
           N+I    +   +F+ L +L  L LD NAL ++P  +  P  +L  +HL+ N I  +  + 
Sbjct: 141 NEISR--LSRGSFEGLESLVKLRLDGNALGALPDAVFAPLGNLLYLHLESNRIRFLGKNA 198

Query: 254 FCKANDTSYIRDRIEEIR 271
           F +     ++     E++
Sbjct: 199 FAQLGKLRFLNLSANELQ 216



 Score = 35.4 bits (80), Expect = 0.061
 Identities = 29/102 (28%), Positives = 45/102 (44%), Gaps = 2/102 (1%)

Query: 129 NKIKKLTAKDFADIPNLRRLDFTGNLIEDIEDGTFSKLSLLEELSLAENQLLKLP--VLP 186
           N ++ L  + F  +P L  L   GN +  +    F  L  L EL L  N+L +LP  +L 
Sbjct: 239 NNLQHLGPRIFQHLPRLGLLSLRGNQLTHLAPEAFWGLEALRELRLEGNRLSQLPTALLE 298

Query: 187 PKLTLFNAKYNKIKSRGIKANAFKKLNNLTFLYLDHNALESV 228
           P  +L     +  +   +    F  L  L  L L +NAL ++
Sbjct: 299 PLHSLEALDLSGNELSALHPATFGHLGRLRELSLRNNALSAL 340



 Score = 28.5 bits (62), Expect = 7.5
 Identities = 37/145 (25%), Positives = 53/145 (36%), Gaps = 32/145 (22%)

Query: 136 AKDFADIPNLRRLDFTGNLIEDIEDGTFSKLSLLEELSLAENQLLKLPVLPPKLTLFNAK 195
           A  FA + +L  L  + N ++ +    F  L  L  LSL  NQL  L             
Sbjct: 222 AATFAPLRSLSSLILSANNLQHLGPRIFQHLPRLGLLSLRGNQLTHL------------- 268

Query: 196 YNKIKSRGIKANAFKKLNNLTFLYLDHNALESVPLNLPE---SLRVIHLQFNNIASITDD 252
                       AF  L  L  L L+ N L  +P  L E   SL  + L  N ++++   
Sbjct: 269 ---------APEAFWGLEALRELRLEGNRLSQLPTALLEPLHSLEALDLSGNELSALHPA 319

Query: 253 TFCKANDTSYIRDRIEEIRLEGNPI 277
           TF           R+ E+ L  N +
Sbjct: 320 TFGHLG-------RLRELSLRNNAL 337



 Score = 28.5 bits (62), Expect = 7.5
 Identities = 18/59 (30%), Positives = 26/59 (44%)

Query: 124 LYARFNKIKKLTAKDFADIPNLRRLDFTGNLIEDIEDGTFSKLSLLEELSLAENQLLKL 182
           L  R N++  L  + F  +  LR L   GN +  +       L  LE L L+ N+L  L
Sbjct: 258 LSLRGNQLTHLAPEAFWGLEALRELRLEGNRLSQLPTALLEPLHSLEALDLSGNELSAL 316


>gi|109809759 leucine rich repeat transmembrane neuronal 3 [Homo
           sapiens]
          Length = 581

 Score = 60.1 bits (144), Expect = 2e-09
 Identities = 50/187 (26%), Positives = 87/187 (46%), Gaps = 17/187 (9%)

Query: 97  CVCLSGSVYCEEVDIDAVP-PLPKESAYLYARFNKIKKLTAKDFADIPNLRRLDFTGNLI 155
           C C    VYCE   +  +P  +      L  R+N ++KL    F  +  L  L    N I
Sbjct: 38  CRCEGKMVYCESQKLQEIPSSISAGCLGLSLRYNSLQKLKYNQFKGLNQLTWLYLDHNHI 97

Query: 156 EDIEDGTFSKLSLLEELSLAENQL---LKLPVLP-PKLTLFNAKYNKIKSRGIKANAFKK 211
            +I++  F+ +  L+EL L+ N++   L     P   L   +  YN++ S G  +  F+ 
Sbjct: 98  SNIDENAFNGIRRLKELILSSNRISYFLNNTFRPVTNLRNLDLSYNQLHSLG--SEQFRG 155

Query: 212 LNNLTFLYLDHNALESVPLNLPE---SLRVIHLQFNNIASITDDTFCKANDTSYIRDRIE 268
           L  L  L+L  N+L ++P+ + +   +L ++ L +N I S+  + F           R++
Sbjct: 156 LRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAG-------MIRLK 208

Query: 269 EIRLEGN 275
           E+ LE N
Sbjct: 209 ELHLEHN 215



 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 50/171 (29%), Positives = 75/171 (43%), Gaps = 16/171 (9%)

Query: 129 NKIKKLTAKDFADIPNLRRLDFTGNLIEDIEDGTFSKLSLLEELSLAENQLLKLPVL--- 185
           N+I       F  + NLR LD + N +  +    F  L  L  L L  N L  +PV    
Sbjct: 119 NRISYFLNNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQ 178

Query: 186 -PPKLTLFNAKYNKIKSRGIKANAFKKLNNLTFLYLDHNALESVPLNL-PE--SLRVIHL 241
               L L +  YN+I+S  +  N F  +  L  L+L+HN    + L L P   SL+ ++L
Sbjct: 179 DCRNLELLDLGYNRIRS--LARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYL 236

Query: 242 QFNNIASITDDTFCKANDTSYIRDRIEEIRLEGNPIVLGKHPNSFICLKRL 292
           Q+N I+ I           S+    ++ + L GN I     P+ F C+  L
Sbjct: 237 QWNKISVI-------GQTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCVPNL 280



 Score = 38.1 bits (87), Expect = 0.009
 Identities = 27/84 (32%), Positives = 41/84 (48%), Gaps = 4/84 (4%)

Query: 124 LYARFNKIKKLTAKDFADIPNLRRLDFTGNLIEDIEDGTFSKLSLLEELSLAENQL--LK 181
           L+ R N ++ +  + F D  NL  LD   N I  +    F+ +  L+EL L  NQ   L 
Sbjct: 162 LHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLN 221

Query: 182 LPVLPPKLTLFN--AKYNKIKSRG 203
           L + P  ++L N   ++NKI   G
Sbjct: 222 LALFPRLVSLQNLYLQWNKISVIG 245


>gi|226342933 podocan-like 1 isoform 2 [Homo sapiens]
          Length = 510

 Score = 59.7 bits (143), Expect = 3e-09
 Identities = 40/134 (29%), Positives = 57/134 (42%), Gaps = 20/134 (14%)

Query: 143 PNLRRLDFTGNLIEDIEDGTFSKLSLLEELSLAENQLLKLPVLPPKLTLFNAKYNKIKSR 202
           P+L RL    NLI  +  G  S+ + L EL L  NQL                       
Sbjct: 214 PSLERLHLQNNLISKVPRGALSRQTQLRELYLQHNQLT--------------------DS 253

Query: 203 GIKANAFKKLNNLTFLYLDHNALESVPLNLPESLRVIHLQFNNIASITDDTFCKANDTSY 262
           G+ A  F KL++L +L L HN L +VP  LP +L ++HL  N I  +       A    Y
Sbjct: 254 GLDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRY 313

Query: 263 IRDRIEEIRLEGNP 276
           +  +  ++   G P
Sbjct: 314 LLLQHNQLGSSGLP 327



 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 51/203 (25%), Positives = 92/203 (45%), Gaps = 38/203 (18%)

Query: 77  EAITPLPPKKENDEMPTC-LLCVCLS-GSVYCEEVDIDAVPP-LPKESAYLYARFNKIKK 133
           E++ PLP          C L C C    +V C+ +D+   P  + + + +L  + N++++
Sbjct: 35  ESLQPLPR--------ACPLRCSCPRVDTVDCDGLDLRVFPDNITRAAQHLSLQNNQLQE 86

Query: 134 LTAKDFADIPNLRRLDFTGNLI--EDIEDGTFSKLSLLEELSLAENQLLKLPVLPPK--- 188
           L   + + +  LR L+   NLI  E + D  F  L+ L+ L +A N+L   P   P+   
Sbjct: 87  LPYNELSRLSGLRTLNLHNNLISSEGLPDEAFESLTQLQHLCVAHNKLSVAPQFLPRSLR 146

Query: 189 ---------LTLFNAKY-------------NKIKSRGIKANAFKKLNNLTFLYLDHNALE 226
                    + +F   +             N++ + G+  +AF+    +  L L +N L 
Sbjct: 147 VADLAANQVMEIFPLTFGEKPALRSVYLHNNQLSNAGLPPDAFRGSEAIATLSLSNNQLS 206

Query: 227 SVPLNLPESLRVIHLQFNNIASI 249
            +P +LP SL  +HLQ N I+ +
Sbjct: 207 YLPPSLPPSLERLHLQNNLISKV 229



 Score = 48.9 bits (115), Expect = 5e-06
 Identities = 50/191 (26%), Positives = 76/191 (39%), Gaps = 34/191 (17%)

Query: 117 LPKESAYLYARFNKIKKLTAKDFADIPNLRRLDFTGNLI--EDIEDGTFSKLSLLEELSL 174
           LP+  A L+   N+I+++ A        LR L    N +    +  G    L  L  L L
Sbjct: 283 LPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHL 342

Query: 175 AENQLLKLP----------VLP---------------PKLTLFNAKYNKIKSRGIKANAF 209
             N L ++P          VLP               P LT  N  YN++ S  +   AF
Sbjct: 343 YGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRAF 402

Query: 210 KKLNNLTFLYLDHNALESVPLNLPESLRVIHLQFNNIASITDDTFCKANDTSYIRDRIEE 269
           ++L  L  L L  N L  +P+ LP  LR + LQ N +  +  +            D++ E
Sbjct: 403 RRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAGL-------DQLRE 455

Query: 270 IRLEGNPIVLG 280
           + L  N + +G
Sbjct: 456 LSLAHNRLRVG 466



 Score = 48.5 bits (114), Expect = 7e-06
 Identities = 34/89 (38%), Positives = 40/89 (44%), Gaps = 4/89 (4%)

Query: 170 EELSLAENQLLKLPVLPPK----LTLFNAKYNKIKSRGIKANAFKKLNNLTFLYLDHNAL 225
           + LSL  NQL +LP         L   N   N I S G+   AF+ L  L  L + HN L
Sbjct: 75  QHLSLQNNQLQELPYNELSRLSGLRTLNLHNNLISSEGLPDEAFESLTQLQHLCVAHNKL 134

Query: 226 ESVPLNLPESLRVIHLQFNNIASITDDTF 254
              P  LP SLRV  L  N +  I   TF
Sbjct: 135 SVAPQFLPRSLRVADLAANQVMEIFPLTF 163



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 38/119 (31%), Positives = 54/119 (45%), Gaps = 6/119 (5%)

Query: 111 IDAVPP-LPKESAYLYARFNKIKKLTAKDFADIPNLRRLDFTGNLIED--IEDGTFSKLS 167
           +D VPP LP+    L    N +  L A+D    P L  L+   N +    +    F +L 
Sbjct: 347 LDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRAFRRLR 406

Query: 168 LLEELSLAENQLLKLPV-LPPKLTLFNAKYNKIKSRGIKANAFKKLNNLTFLYLDHNAL 225
            L  L LA NQL +LP+ LP  L     + N++  R ++      L+ L  L L HN L
Sbjct: 407 ALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQL--RMLEPEPLAGLDQLRELSLAHNRL 463


>gi|226342931 podocan-like 1 isoform 1 [Homo sapiens]
          Length = 512

 Score = 59.7 bits (143), Expect = 3e-09
 Identities = 40/134 (29%), Positives = 57/134 (42%), Gaps = 20/134 (14%)

Query: 143 PNLRRLDFTGNLIEDIEDGTFSKLSLLEELSLAENQLLKLPVLPPKLTLFNAKYNKIKSR 202
           P+L RL    NLI  +  G  S+ + L EL L  NQL                       
Sbjct: 216 PSLERLHLQNNLISKVPRGALSRQTQLRELYLQHNQLT--------------------DS 255

Query: 203 GIKANAFKKLNNLTFLYLDHNALESVPLNLPESLRVIHLQFNNIASITDDTFCKANDTSY 262
           G+ A  F KL++L +L L HN L +VP  LP +L ++HL  N I  +       A    Y
Sbjct: 256 GLDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRY 315

Query: 263 IRDRIEEIRLEGNP 276
           +  +  ++   G P
Sbjct: 316 LLLQHNQLGSSGLP 329



 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 51/203 (25%), Positives = 92/203 (45%), Gaps = 38/203 (18%)

Query: 77  EAITPLPPKKENDEMPTC-LLCVCLS-GSVYCEEVDIDAVPP-LPKESAYLYARFNKIKK 133
           E++ PLP          C L C C    +V C+ +D+   P  + + + +L  + N++++
Sbjct: 37  ESLQPLPR--------ACPLRCSCPRVDTVDCDGLDLRVFPDNITRAAQHLSLQNNQLQE 88

Query: 134 LTAKDFADIPNLRRLDFTGNLI--EDIEDGTFSKLSLLEELSLAENQLLKLPVLPPK--- 188
           L   + + +  LR L+   NLI  E + D  F  L+ L+ L +A N+L   P   P+   
Sbjct: 89  LPYNELSRLSGLRTLNLHNNLISSEGLPDEAFESLTQLQHLCVAHNKLSVAPQFLPRSLR 148

Query: 189 ---------LTLFNAKY-------------NKIKSRGIKANAFKKLNNLTFLYLDHNALE 226
                    + +F   +             N++ + G+  +AF+    +  L L +N L 
Sbjct: 149 VADLAANQVMEIFPLTFGEKPALRSVYLHNNQLSNAGLPPDAFRGSEAIATLSLSNNQLS 208

Query: 227 SVPLNLPESLRVIHLQFNNIASI 249
            +P +LP SL  +HLQ N I+ +
Sbjct: 209 YLPPSLPPSLERLHLQNNLISKV 231



 Score = 48.9 bits (115), Expect = 5e-06
 Identities = 50/191 (26%), Positives = 76/191 (39%), Gaps = 34/191 (17%)

Query: 117 LPKESAYLYARFNKIKKLTAKDFADIPNLRRLDFTGNLI--EDIEDGTFSKLSLLEELSL 174
           LP+  A L+   N+I+++ A        LR L    N +    +  G    L  L  L L
Sbjct: 285 LPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHL 344

Query: 175 AENQLLKLP----------VLP---------------PKLTLFNAKYNKIKSRGIKANAF 209
             N L ++P          VLP               P LT  N  YN++ S  +   AF
Sbjct: 345 YGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRAF 404

Query: 210 KKLNNLTFLYLDHNALESVPLNLPESLRVIHLQFNNIASITDDTFCKANDTSYIRDRIEE 269
           ++L  L  L L  N L  +P+ LP  LR + LQ N +  +  +            D++ E
Sbjct: 405 RRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAGL-------DQLRE 457

Query: 270 IRLEGNPIVLG 280
           + L  N + +G
Sbjct: 458 LSLAHNRLRVG 468



 Score = 48.5 bits (114), Expect = 7e-06
 Identities = 34/89 (38%), Positives = 40/89 (44%), Gaps = 4/89 (4%)

Query: 170 EELSLAENQLLKLPVLPPK----LTLFNAKYNKIKSRGIKANAFKKLNNLTFLYLDHNAL 225
           + LSL  NQL +LP         L   N   N I S G+   AF+ L  L  L + HN L
Sbjct: 77  QHLSLQNNQLQELPYNELSRLSGLRTLNLHNNLISSEGLPDEAFESLTQLQHLCVAHNKL 136

Query: 226 ESVPLNLPESLRVIHLQFNNIASITDDTF 254
              P  LP SLRV  L  N +  I   TF
Sbjct: 137 SVAPQFLPRSLRVADLAANQVMEIFPLTF 165



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 38/119 (31%), Positives = 54/119 (45%), Gaps = 6/119 (5%)

Query: 111 IDAVPP-LPKESAYLYARFNKIKKLTAKDFADIPNLRRLDFTGNLIED--IEDGTFSKLS 167
           +D VPP LP+    L    N +  L A+D    P L  L+   N +    +    F +L 
Sbjct: 349 LDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRAFRRLR 408

Query: 168 LLEELSLAENQLLKLPV-LPPKLTLFNAKYNKIKSRGIKANAFKKLNNLTFLYLDHNAL 225
            L  L LA NQL +LP+ LP  L     + N++  R ++      L+ L  L L HN L
Sbjct: 409 ALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQL--RMLEPEPLAGLDQLRELSLAHNRL 465


>gi|40217820 slit and trk like 3 protein [Homo sapiens]
          Length = 977

 Score = 59.7 bits (143), Expect = 3e-09
 Identities = 49/178 (27%), Positives = 83/178 (46%), Gaps = 21/178 (11%)

Query: 80  TPLPPKKENDEM--PTCLLCVCLSGS----VYCEE---VDIDAVPPLPKESAYLYARFNK 130
           TP+P  ++++E+  P    C C        ++C+     +I  +         LY + N 
Sbjct: 29  TPIPLIEDSEEIDEPCFDPCYCEVKESLFHIHCDSKGFTNISQITEFWSRPFKLYLQRNS 88

Query: 131 IKKLTAKDFADIPNLRRLDFTGNLIEDIEDGTFSKLSLLEELSLAENQLLKLPVLP---- 186
           ++KL    F  + N   ++   N ++DI+ G F+ L +L+ L L EN   KL V      
Sbjct: 89  MRKLYTNSFLHLNNAVSINLGNNALQDIQTGAFNGLKILKRLYLHEN---KLDVFRNDTF 145

Query: 187 ---PKLTLFNAKYNKIKSRGIKANAFKKLNNLTFLYLDHNALESVPLNLPESLRVIHL 241
                L    A YN IK   I++ AF+ L+ L  L L+ N +  +P NL +++ + HL
Sbjct: 146 LGLESLEYLQADYNVIKR--IESGAFRNLSKLRVLILNDNLIPMLPTNLFKAVSLTHL 201



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 55/199 (27%), Positives = 85/199 (42%), Gaps = 14/199 (7%)

Query: 44  SQDYEDKYLDGKNIKEKETVIIPNEKSLQLQKDEAITPLPPKKENDEMPTCLL--CVC-- 99
           S +Y+      K  K+  T   P+  S  L       P+ P +    +P      C C  
Sbjct: 323 SVEYKSSNKQPKPTKQPRTPRPPST-SQALYPGPNQPPIAPYQTRPPIPIICPTGCTCNL 381

Query: 100 ----LSGSVYCEEV---DIDAVPPLPKESAYLYARFNKIKKLTAKDFADIPNLRRLDFTG 152
               L  +V C+E    +I  + P P  +  LY   N I+K+   DF +  +L  L    
Sbjct: 382 HINDLGLTVNCKERGFNNISELLPRPLNAKKLYLSSNLIQKIYRSDFWNFSSLDLLHLGN 441

Query: 153 NLIEDIEDGTFSKLSLLEELSLAENQLLKL-PVLPPKLTLFNAKYNKIK-SRGIKANAFK 210
           N I  ++DG F  L  L+ L L  N + KL P +   L   +  Y +    R I+  AF 
Sbjct: 442 NRISYVQDGAFINLPNLKSLFLNGNDIEKLTPGMFRGLQSLHYLYFEFNVIREIQPAAFS 501

Query: 211 KLNNLTFLYLDHNALESVP 229
            + NL  L+L++N L ++P
Sbjct: 502 LMPNLKLLFLNNNLLRTLP 520



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 23/62 (37%), Positives = 34/62 (54%), Gaps = 1/62 (1%)

Query: 123 YLYARFNKIKKLTAKDFADIPNLRRLDFTGNLIEDIEDGTFSKLSLLEELSLAENQLLKL 182
           YLY  FN I+++    F+ +PNL+ L    NL+  +    F+  S L  L+L +N  L L
Sbjct: 484 YLYFEFNVIREIQPAAFSLMPNLKLLFLNNNLLRTLPTDAFAGTS-LARLNLRKNYFLYL 542

Query: 183 PV 184
           PV
Sbjct: 543 PV 544


>gi|4502403 biglycan preproprotein [Homo sapiens]
          Length = 368

 Score = 59.3 bits (142), Expect = 4e-09
 Identities = 47/179 (26%), Positives = 78/179 (43%), Gaps = 27/179 (15%)

Query: 97  CVCLSGSVYCEEVDIDAVPP-LPKESAYLYARFNKIKKLTAKDFADIPNLRRLDFTGNLI 155
           C C    V C ++ + +VP  +  ++  L  + N I +L   DF  + +L  L    N I
Sbjct: 67  CHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKI 126

Query: 156 EDIEDGTFSKLSLLEELSLAENQLLKLPV-LPPKLTLFNAKYNKIK-------------- 200
             I +  FS L  L++L +++N L+++P  LP  L       N+I+              
Sbjct: 127 SKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMN 186

Query: 201 ----------SRGIKANAFKKLNNLTFLYLDHNALESVPLNLPESLRVIHLQFNNIASI 249
                     + G +  AF  L  L +L +    L  +P +LPE+L  +HL  N I +I
Sbjct: 187 CIEMGGNPLENSGFEPGAFDGLK-LNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAI 244



 Score = 55.8 bits (133), Expect = 4e-08
 Identities = 56/207 (27%), Positives = 90/207 (43%), Gaps = 30/207 (14%)

Query: 111 IDAVPPLPKESAYLYARFNKIKKLTAKDFADIPNLRRLDFTGNLIED--IEDGTFSKLSL 168
           ++  P LP     L    N+I+K+    F+ + N+  ++  GN +E+   E G F  L L
Sbjct: 151 VEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKL 210

Query: 169 LEELSLAENQLLKLPV-LPPKLTLFNAKYNKIKS----------------------RGIK 205
              L ++E +L  +P  LP  L   +  +NKI++                      R I+
Sbjct: 211 -NYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIE 269

Query: 206 ANAFKKLNNLTFLYLDHNALESVPLNLPE--SLRVIHLQFNNIASITDDTFCKANDTSYI 263
             +   L  L  L+LD+N L  VP  LP+   L+V++L  NNI  +  + FC        
Sbjct: 270 NGSLSFLPTLRELHLDNNKLARVPSGLPDLKLLQVVYLHSNNITKVGVNDFCPMG-FGVK 328

Query: 264 RDRIEEIRLEGNPIVLGK-HPNSFICL 289
           R     I L  NP+   +  P +F C+
Sbjct: 329 RAYYNGISLFNNPVPYWEVQPATFRCV 355



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 33/101 (32%), Positives = 46/101 (45%), Gaps = 4/101 (3%)

Query: 108 EVDIDAVPP-LPKESAYLYARFNKIKKLTAKDFADIPNLRRLDFTGNLIEDIEDGTFSKL 166
           E  +  +P  LP+    L+   NKI+ +  +D      L RL    N I  IE+G+ S L
Sbjct: 217 EAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFL 276

Query: 167 SLLEELSLAENQLLKLPVLPPKLTLFNAKY---NKIKSRGI 204
             L EL L  N+L ++P   P L L    Y   N I   G+
Sbjct: 277 PTLRELHLDNNKLARVPSGLPDLKLLQVVYLHSNNITKVGV 317



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 41/149 (27%), Positives = 57/149 (38%), Gaps = 30/149 (20%)

Query: 143 PNLRRLDFTGNLIEDIEDGTFSKLSLLEELSLAENQLLKLPVLPPKLTLFNAKYNKIKSR 202
           P+   LD   N I ++    F  L  L  L L  N++ K                     
Sbjct: 90  PDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISK--------------------- 128

Query: 203 GIKANAFKKLNNLTFLYLDHNALESVPLNLPESLRVIHLQFNNIASITDDTFCKANDTSY 262
            I   AF  L  L  LY+  N L  +P NLP SL  + +  N I  +    F      S 
Sbjct: 129 -IHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVF------SG 181

Query: 263 IRDRIEEIRLEGNPIV-LGKHPNSFICLK 290
           +R+ +  I + GNP+   G  P +F  LK
Sbjct: 182 LRN-MNCIEMGGNPLENSGFEPGAFDGLK 209


>gi|126517478 peroxidasin homolog-like [Homo sapiens]
          Length = 1463

 Score = 59.3 bits (142), Expect = 4e-09
 Identities = 47/191 (24%), Positives = 80/191 (41%), Gaps = 32/191 (16%)

Query: 91  MPTCLLCVCLSGSVYCEEVDIDAVPPLPKESAYLYARFNKIKKLTAKDFADIPNLRRLDF 150
           +P    C+C   +V C  + +D +P +P+++  L  RFN+I+++    F  + NL  L  
Sbjct: 22  LPCPSRCLCFKSTVRCMHLMLDHIPQVPQQTTVLDLRFNRIREIPGSAFKKLKNLNTLLL 81

Query: 151 TGNLIEDIEDGTFSKLSLLEELSLAENQLLKLPVLPPKLTLFNAKYNKIKSRGIKANAFK 210
             N I  I    F  L  L  L L +N++                        +    FK
Sbjct: 82  NNNHIRKISRNAFEGLENLLYLYLYKNEI----------------------HALDKQTFK 119

Query: 211 KLNNLTFLYLDHNALESV-PLNLPESLRV--IHLQFNNIASITDDTFCKANDTSYIRDRI 267
            L +L  LY+  N LE + P    + LR+  + L  N ++ I   +F          D +
Sbjct: 120 GLISLEHLYIHFNQLEMLQPETFGDLLRLERLFLHNNKLSKIPAGSFSNL-------DSL 172

Query: 268 EEIRLEGNPIV 278
           + +RL+ N +V
Sbjct: 173 KRLRLDSNALV 183


>gi|27436867 slit and trk like 4 protein [Homo sapiens]
          Length = 837

 Score = 59.3 bits (142), Expect = 4e-09
 Identities = 53/181 (29%), Positives = 78/181 (43%), Gaps = 13/181 (7%)

Query: 103 SVYCEEVDIDAVP---PLPKESAYLYARFNKIKKLTAKDFADIPNLRRLDFTGNLIEDIE 159
           SV C+E +I ++    P P  +  L+   N IK +   DF D   L  L    N I  I+
Sbjct: 358 SVNCQEKNIQSMSELIPKPLNAKKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIK 417

Query: 160 DGTFSKLSLLEELSLAENQLLKL-PVL---PPKLTLFNAKYNKIKSRGIKANAFKKLNNL 215
              F  L+ L  L L  NQ+ +L P +      L     +YN IK   I A  F  + NL
Sbjct: 418 GDVFHNLTNLRRLYLNGNQIERLYPEIFSGLHNLQYLYLEYNLIKE--ISAGTFDSMPNL 475

Query: 216 TFLYLDHNALESVPLNLPESLRVIHLQFNNIASITDDTFCKANDTSYIRDRIEEIRLEGN 275
             LYL++N L+S+P+ +     +  L   N        +   +        + +I LEGN
Sbjct: 476 QLLYLNNNLLKSLPVYIFSGAPLARLNLRN----NKFMYLPVSGVLDQLQSLTQIDLEGN 531

Query: 276 P 276
           P
Sbjct: 532 P 532



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 57/196 (29%), Positives = 84/196 (42%), Gaps = 21/196 (10%)

Query: 94  CLLCVCLSGS----VYCEEVDIDAVPPL-PKESAYLYARF--NKIKKLTAKDFADIPNLR 146
           C +C C+S      V CE+V +     L P  S + +  F  N +  L    F +  +  
Sbjct: 27  CNVCSCVSVENVLYVNCEKVSVYRPNQLKPPWSNFYHLNFQNNFLNILYPNTFLNFSHAV 86

Query: 147 RLDFTGNLIEDIEDGTFSKLSLLEELSLAENQLLKLPVLP----PKLTLFNAKYNKIKSR 202
            L    N +++IE G F  LS L++L L  N+L  L          L    A YN IK  
Sbjct: 87  SLHLGNNKLQNIEGGAFLGLSALKQLHLNNNELKILRADTFLGIENLEYLQADYNLIKY- 145

Query: 203 GIKANAFKKLNNLTFLYLDHNALESVPLNLPESLRVIHLQF--NNIASITDDTFCKANDT 260
            I+  AF KL+ L  L L+ N +  +P N+     + HL    N I  +           
Sbjct: 146 -IERGAFNKLHKLKVLILNDNLISFLPDNIFRFASLTHLDIRGNRIQKLP-----YIGVL 199

Query: 261 SYIRDRIEEIRLEGNP 276
            +I  R+ E++LE NP
Sbjct: 200 EHI-GRVVELQLEDNP 214


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.138    0.397 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,880,705
Number of Sequences: 37866
Number of extensions: 540190
Number of successful extensions: 2794
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 153
Number of HSP's successfully gapped in prelim test: 104
Number of HSP's that attempted gapping in prelim test: 1669
Number of HSP's gapped (non-prelim): 762
length of query: 298
length of database: 18,247,518
effective HSP length: 102
effective length of query: 196
effective length of database: 14,385,186
effective search space: 2819496456
effective search space used: 2819496456
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.