Guide to the Human Genome
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Search of human proteins with 148235002

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|148235002 TBC1 domain family, member 26 [Homo sapiens]
         (250 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|148235002 TBC1 domain family, member 26 [Homo sapiens]             509   e-145
gi|239756750 PREDICTED: similar to TBC1 domain family, member 28...   359   1e-99
gi|151108489 TBC1 domain family, member 28 [Homo sapiens]             354   5e-98
gi|109638751 ubiquitin specific protease 6 [Homo sapiens]             241   3e-64
gi|90577185 TBC1 domain family member 3C [Homo sapiens]               238   5e-63
gi|157502205 TBC1 domain family, member 3G [Homo sapiens]             238   5e-63
gi|183583565 TBC1 domain family, member 3 [Homo sapiens]              236   1e-62
gi|183583567 TBC1 domain family, member 3E [Homo sapiens]             236   1e-62
gi|183583563 TBC1 domain family, member 3D [Homo sapiens]             236   1e-62
gi|226693407 TBC1 domain family, member 3H [Homo sapiens]             236   1e-62
gi|149999613 TBC1 domain family, member 3B [Homo sapiens]             236   1e-62
gi|14149985 TBC1 domain family, member 3F [Homo sapiens]              233   9e-62
gi|7661864 USP6 N-terminal like isoform 1 [Homo sapiens]              178   3e-45
gi|122937432 USP6 N-terminal like isoform 2 [Homo sapiens]            178   3e-45
gi|239756926 PREDICTED: similar to TBC1 domain family, member 3 ...   149   3e-36
gi|13994322 TBC1 domain family, member 10A [Homo sapiens]              93   2e-19
gi|167614488 TBC1 domain family, member 10B [Homo sapiens]             92   6e-19
gi|38348348 TBC1 domain family, member 10C [Homo sapiens]              86   4e-17
gi|139394668 TBC1 domain family, member 9 (with GRAM domain) [Ho...    71   8e-13
gi|50658061 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member...    69   3e-12
gi|148806902 TBC1 domain family, member 12 [Homo sapiens]              67   1e-11
gi|156231067 TBC1 domain family, member 8 [Homo sapiens]               66   3e-11
gi|38570103 TBC1 domain family, member 8B (with GRAM domain) iso...    65   6e-11
gi|38570101 TBC1 domain family, member 8B (with GRAM domain) iso...    65   6e-11
gi|164519084 RAB GTPase activating protein 1 [Homo sapiens]            65   7e-11
gi|118722351 growth hormone regulated TBC protein 1 [Homo sapiens]     65   7e-11
gi|164565381 TBC1 domain family, member 14 isoform b [Homo sapiens]    62   4e-10
gi|164565368 TBC1 domain family, member 14 isoform a [Homo sapiens]    62   4e-10
gi|164565366 TBC1 domain family, member 14 isoform a [Homo sapiens]    62   4e-10
gi|45597177 TBC1 domain family, member 9B (with GRAM domain) iso...    62   6e-10

>gi|148235002 TBC1 domain family, member 26 [Homo sapiens]
          Length = 250

 Score =  509 bits (1312), Expect = e-145
 Identities = 250/250 (100%), Positives = 250/250 (100%)

Query: 1   MEMDGDPYNLPAQGQGNIIITKYEQGHRAGAAVDLGHEQVDVRKYTNNLGIVHEMELPRV 60
           MEMDGDPYNLPAQGQGNIIITKYEQGHRAGAAVDLGHEQVDVRKYTNNLGIVHEMELPRV
Sbjct: 1   MEMDGDPYNLPAQGQGNIIITKYEQGHRAGAAVDLGHEQVDVRKYTNNLGIVHEMELPRV 60

Query: 61  SALEVKQRRKESKRTNKWQKMLADWTKYRSTKKLSQRVYKVIPLAVRGRAWSLLLDIDRI 120
           SALEVKQRRKESKRTNKWQKMLADWTKYRSTKKLSQRVYKVIPLAVRGRAWSLLLDIDRI
Sbjct: 61  SALEVKQRRKESKRTNKWQKMLADWTKYRSTKKLSQRVYKVIPLAVRGRAWSLLLDIDRI 120

Query: 121 KSQNPGKYKVMKEKGKRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAY 180
           KSQNPGKYKVMKEKGKRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAY
Sbjct: 121 KSQNPGKYKVMKEKGKRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAY 180

Query: 181 NPEVGYHRDLSRITAILLLCLPEEDAFWALTQLLAGERHSLWYSTAQILPGSRGSYRTRS 240
           NPEVGYHRDLSRITAILLLCLPEEDAFWALTQLLAGERHSLWYSTAQILPGSRGSYRTRS
Sbjct: 181 NPEVGYHRDLSRITAILLLCLPEEDAFWALTQLLAGERHSLWYSTAQILPGSRGSYRTRS 240

Query: 241 RCCTSPSQRS 250
           RCCTSPSQRS
Sbjct: 241 RCCTSPSQRS 250


>gi|239756750 PREDICTED: similar to TBC1 domain family, member 28
           [Homo sapiens]
          Length = 234

 Score =  359 bits (921), Expect = 1e-99
 Identities = 178/182 (97%), Positives = 179/182 (98%)

Query: 1   MEMDGDPYNLPAQGQGNIIITKYEQGHRAGAAVDLGHEQVDVRKYTNNLGIVHEMELPRV 60
           MEMDGDPYNLPAQGQGNIIITKYEQGHRAGAAVDLGHEQVDVRKYTNNLGIVHEMELP V
Sbjct: 25  MEMDGDPYNLPAQGQGNIIITKYEQGHRAGAAVDLGHEQVDVRKYTNNLGIVHEMELPHV 84

Query: 61  SALEVKQRRKESKRTNKWQKMLADWTKYRSTKKLSQRVYKVIPLAVRGRAWSLLLDIDRI 120
           SALEVKQRRKESKRTNKWQKMLADWTKYRSTKKLSQRV KVIPLAVRGRA SLLLDID+I
Sbjct: 85  SALEVKQRRKESKRTNKWQKMLADWTKYRSTKKLSQRVCKVIPLAVRGRALSLLLDIDKI 144

Query: 121 KSQNPGKYKVMKEKGKRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAY 180
           KSQNPGKYKVMKEKGKRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAY
Sbjct: 145 KSQNPGKYKVMKEKGKRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAY 204

Query: 181 NP 182
           NP
Sbjct: 205 NP 206


>gi|151108489 TBC1 domain family, member 28 [Homo sapiens]
          Length = 210

 Score =  354 bits (908), Expect = 5e-98
 Identities = 177/182 (97%), Positives = 178/182 (97%)

Query: 1   MEMDGDPYNLPAQGQGNIIITKYEQGHRAGAAVDLGHEQVDVRKYTNNLGIVHEMELPRV 60
           MEMD DP NLPAQGQGNIIITKYEQGHRAGAAVDLGHEQVDVRKYTNNLGIVHEMELPRV
Sbjct: 1   MEMDEDPDNLPAQGQGNIIITKYEQGHRAGAAVDLGHEQVDVRKYTNNLGIVHEMELPRV 60

Query: 61  SALEVKQRRKESKRTNKWQKMLADWTKYRSTKKLSQRVYKVIPLAVRGRAWSLLLDIDRI 120
           SALEVKQRRKESKRTNKWQKMLADWTKYRSTKKLSQRV KVIPLAVRGRA SLLLDID+I
Sbjct: 61  SALEVKQRRKESKRTNKWQKMLADWTKYRSTKKLSQRVCKVIPLAVRGRALSLLLDIDKI 120

Query: 121 KSQNPGKYKVMKEKGKRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAY 180
           KSQNPGKYKVMKEKGKRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAY
Sbjct: 121 KSQNPGKYKVMKEKGKRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAY 180

Query: 181 NP 182
           NP
Sbjct: 181 NP 182


>gi|109638751 ubiquitin specific protease 6 [Homo sapiens]
          Length = 1406

 Score =  241 bits (616), Expect = 3e-64
 Identities = 123/221 (55%), Positives = 158/221 (71%), Gaps = 1/221 (0%)

Query: 1   MEMDGDPYNLPAQGQGNIIITKYEQGHRAGAAVDLGHEQVDVRKYTNNLGIVHEMELPRV 60
           M+M  +  +L AQ + +I++ KY++GHRAG   D G E V +    +  GI+HE ELP V
Sbjct: 1   MDMVENADSLQAQERKDILM-KYDKGHRAGLPEDKGPEPVGINSSIDRFGILHETELPPV 59

Query: 61  SALEVKQRRKESKRTNKWQKMLADWTKYRSTKKLSQRVYKVIPLAVRGRAWSLLLDIDRI 120
           +A E K+ R+E  RT+KW +ML +W  Y+ + KL  RVYK IP+ +RG  WS+LL+I  I
Sbjct: 60  TAREAKKIRREMTRTSKWMEMLGEWETYKHSSKLIDRVYKGIPMNIRGPVWSVLLNIQEI 119

Query: 121 KSQNPGKYKVMKEKGKRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAY 180
           K +NPG+Y++MKE+GKRSS  IH I LDV  TL+ H+ F  R+G KQ+EL  IL+AYS Y
Sbjct: 120 KLKNPGRYQIMKERGKRSSEHIHHIDLDVRTTLRNHVFFRDRYGAKQRELFYILLAYSEY 179

Query: 181 NPEVGYHRDLSRITAILLLCLPEEDAFWALTQLLAGERHSL 221
           NPEVGY RDLS ITA+ LL LPEEDAFWAL QLLA ERHSL
Sbjct: 180 NPEVGYCRDLSHITALFLLYLPEEDAFWALVQLLASERHSL 220


>gi|90577185 TBC1 domain family member 3C [Homo sapiens]
          Length = 549

 Score =  238 bits (606), Expect = 5e-63
 Identities = 122/206 (59%), Positives = 148/206 (71%), Gaps = 5/206 (2%)

Query: 19  IITKYEQGHRAGAAVDLGHEQVDVRKYTNN---LGIVHEMELPRVSALEVKQRRKESKRT 75
           II KYE+GHRAG   D G +    R Y NN   LGIVHE ELP ++A E KQ R+E  R 
Sbjct: 18  IIMKYEKGHRAGLPEDKGPKPF--RSYNNNVDHLGIVHETELPPLTAREAKQIRREISRK 75

Query: 76  NKWQKMLADWTKYRSTKKLSQRVYKVIPLAVRGRAWSLLLDIDRIKSQNPGKYKVMKEKG 135
           +KW  ML DW KY+S++KL  R YK +P+ +RG  WS+LL+I+ +K +NPG+Y++MKEKG
Sbjct: 76  SKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKG 135

Query: 136 KRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYNPEVGYHRDLSRITA 195
           KRSS  I  I  D+S TL+KHM F  R+G KQ+EL  IL+AY  YNPEVGY RDLS I A
Sbjct: 136 KRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAA 195

Query: 196 ILLLCLPEEDAFWALTQLLAGERHSL 221
           + LL LPEEDAFWAL QLLA ERHSL
Sbjct: 196 LFLLYLPEEDAFWALVQLLASERHSL 221


>gi|157502205 TBC1 domain family, member 3G [Homo sapiens]
          Length = 549

 Score =  238 bits (606), Expect = 5e-63
 Identities = 122/206 (59%), Positives = 148/206 (71%), Gaps = 5/206 (2%)

Query: 19  IITKYEQGHRAGAAVDLGHEQVDVRKYTNN---LGIVHEMELPRVSALEVKQRRKESKRT 75
           II KYE+GHRAG   D G +    R Y NN   LGIVHE ELP ++A E KQ R+E  R 
Sbjct: 18  IIMKYEKGHRAGLPEDKGPKPF--RSYNNNVDHLGIVHETELPPLTAREAKQIRREISRK 75

Query: 76  NKWQKMLADWTKYRSTKKLSQRVYKVIPLAVRGRAWSLLLDIDRIKSQNPGKYKVMKEKG 135
           +KW  ML DW KY+S++KL  R YK +P+ +RG  WS+LL+I+ +K +NPG+Y++MKEKG
Sbjct: 76  SKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKG 135

Query: 136 KRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYNPEVGYHRDLSRITA 195
           KRSS  I  I  D+S TL+KHM F  R+G KQ+EL  IL+AY  YNPEVGY RDLS I A
Sbjct: 136 KRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAA 195

Query: 196 ILLLCLPEEDAFWALTQLLAGERHSL 221
           + LL LPEEDAFWAL QLLA ERHSL
Sbjct: 196 LFLLYLPEEDAFWALVQLLASERHSL 221


>gi|183583565 TBC1 domain family, member 3 [Homo sapiens]
          Length = 549

 Score =  236 bits (603), Expect = 1e-62
 Identities = 122/206 (59%), Positives = 148/206 (71%), Gaps = 5/206 (2%)

Query: 19  IITKYEQGHRAGAAVDLGHEQVDVRKYTNN---LGIVHEMELPRVSALEVKQRRKESKRT 75
           II KYE+GHRAG   D G +    R Y NN   LGIVHE ELP ++A E KQ R+E  R 
Sbjct: 18  IIMKYEKGHRAGLPEDKGPKPF--RSYNNNVDHLGIVHETELPPLTAREAKQIRREISRK 75

Query: 76  NKWQKMLADWTKYRSTKKLSQRVYKVIPLAVRGRAWSLLLDIDRIKSQNPGKYKVMKEKG 135
           +KW  ML DW KY+S++KL  R YK +P+ +RG  WS+LL+I+ +K +NPG+Y++MKEKG
Sbjct: 76  SKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKG 135

Query: 136 KRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYNPEVGYHRDLSRITA 195
           KRSS  I  I  DVS TL+KH+ F  R+G KQ+EL  IL+AY  YNPEVGY RDLS I A
Sbjct: 136 KRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAA 195

Query: 196 ILLLCLPEEDAFWALTQLLAGERHSL 221
           + LL LPEEDAFWAL QLLA ERHSL
Sbjct: 196 LFLLYLPEEDAFWALVQLLASERHSL 221


>gi|183583567 TBC1 domain family, member 3E [Homo sapiens]
          Length = 549

 Score =  236 bits (603), Expect = 1e-62
 Identities = 122/206 (59%), Positives = 148/206 (71%), Gaps = 5/206 (2%)

Query: 19  IITKYEQGHRAGAAVDLGHEQVDVRKYTNN---LGIVHEMELPRVSALEVKQRRKESKRT 75
           II KYE+GHRAG   D G +    R Y NN   LGIVHE ELP ++A E KQ R+E  R 
Sbjct: 18  IIMKYEKGHRAGLPEDKGPKPF--RSYNNNVDHLGIVHETELPPLTAREAKQIRREISRK 75

Query: 76  NKWQKMLADWTKYRSTKKLSQRVYKVIPLAVRGRAWSLLLDIDRIKSQNPGKYKVMKEKG 135
           +KW  ML DW KY+S++KL  R YK +P+ +RG  WS+LL+I+ +K +NPG+Y++MKEKG
Sbjct: 76  SKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKG 135

Query: 136 KRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYNPEVGYHRDLSRITA 195
           KRSS  I  I  DVS TL+KH+ F  R+G KQ+EL  IL+AY  YNPEVGY RDLS I A
Sbjct: 136 KRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAA 195

Query: 196 ILLLCLPEEDAFWALTQLLAGERHSL 221
           + LL LPEEDAFWAL QLLA ERHSL
Sbjct: 196 LFLLYLPEEDAFWALVQLLASERHSL 221


>gi|183583563 TBC1 domain family, member 3D [Homo sapiens]
          Length = 549

 Score =  236 bits (603), Expect = 1e-62
 Identities = 122/206 (59%), Positives = 148/206 (71%), Gaps = 5/206 (2%)

Query: 19  IITKYEQGHRAGAAVDLGHEQVDVRKYTNN---LGIVHEMELPRVSALEVKQRRKESKRT 75
           II KYE+GHRAG   D G +    R Y NN   LGIVHE ELP ++A E KQ R+E  R 
Sbjct: 18  IIMKYEKGHRAGLPEDKGPKPF--RSYNNNVDHLGIVHETELPPLTAREAKQIRREISRK 75

Query: 76  NKWQKMLADWTKYRSTKKLSQRVYKVIPLAVRGRAWSLLLDIDRIKSQNPGKYKVMKEKG 135
           +KW  ML DW KY+S++KL  R YK +P+ +RG  WS+LL+I+ +K +NPG+Y++MKEKG
Sbjct: 76  SKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKG 135

Query: 136 KRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYNPEVGYHRDLSRITA 195
           KRSS  I  I  DVS TL+KH+ F  R+G KQ+EL  IL+AY  YNPEVGY RDLS I A
Sbjct: 136 KRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAA 195

Query: 196 ILLLCLPEEDAFWALTQLLAGERHSL 221
           + LL LPEEDAFWAL QLLA ERHSL
Sbjct: 196 LFLLYLPEEDAFWALVQLLASERHSL 221


>gi|226693407 TBC1 domain family, member 3H [Homo sapiens]
          Length = 549

 Score =  236 bits (602), Expect = 1e-62
 Identities = 121/206 (58%), Positives = 148/206 (71%), Gaps = 5/206 (2%)

Query: 19  IITKYEQGHRAGAAVDLGHEQVDVRKYTNN---LGIVHEMELPRVSALEVKQRRKESKRT 75
           II KYE+GH+AG   D G +    R Y NN   LGIVHE ELP ++A E KQ R+E  R 
Sbjct: 18  IIMKYEKGHQAGLPEDKGPKPF--RSYNNNVDHLGIVHETELPPLTAREAKQIRREISRK 75

Query: 76  NKWQKMLADWTKYRSTKKLSQRVYKVIPLAVRGRAWSLLLDIDRIKSQNPGKYKVMKEKG 135
           +KW  ML DW KY+S++KL  R YK +P+ +RG  WS+LL+I+ +K +NPG+Y++MKEKG
Sbjct: 76  SKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKG 135

Query: 136 KRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYNPEVGYHRDLSRITA 195
           KRSS  I  I  D+S TL+KHM F  R+G KQ+EL  IL+AY  YNPEVGY RDLS I A
Sbjct: 136 KRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAA 195

Query: 196 ILLLCLPEEDAFWALTQLLAGERHSL 221
           + LL LPEEDAFWAL QLLA ERHSL
Sbjct: 196 LFLLYLPEEDAFWALVQLLASERHSL 221


>gi|149999613 TBC1 domain family, member 3B [Homo sapiens]
          Length = 549

 Score =  236 bits (602), Expect = 1e-62
 Identities = 121/206 (58%), Positives = 147/206 (71%), Gaps = 5/206 (2%)

Query: 19  IITKYEQGHRAGAAVDLGHEQVDVRKYTNN---LGIVHEMELPRVSALEVKQRRKESKRT 75
           II KYE+GHRAG   D G +    R Y NN   LGIVHE ELP ++A E KQ R+E  R 
Sbjct: 18  IIMKYEKGHRAGLPEDKGPKPF--RSYNNNVDHLGIVHETELPPLTAREAKQIRREISRK 75

Query: 76  NKWQKMLADWTKYRSTKKLSQRVYKVIPLAVRGRAWSLLLDIDRIKSQNPGKYKVMKEKG 135
           +KW  ML DW KY+S++KL  R YK +P+ +RG  WS+LL+I+ +K +NPG+Y++MKEKG
Sbjct: 76  SKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKG 135

Query: 136 KRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYNPEVGYHRDLSRITA 195
           KRSS  I  I  D+S TL+KHM F  R+G KQ+EL  IL+AY  YNPEVGY RDLS I A
Sbjct: 136 KRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAA 195

Query: 196 ILLLCLPEEDAFWALTQLLAGERHSL 221
           + LL  PEEDAFWAL QLLA ERHSL
Sbjct: 196 LFLLYFPEEDAFWALVQLLASERHSL 221


>gi|14149985 TBC1 domain family, member 3F [Homo sapiens]
          Length = 549

 Score =  233 bits (595), Expect = 9e-62
 Identities = 120/206 (58%), Positives = 147/206 (71%), Gaps = 5/206 (2%)

Query: 19  IITKYEQGHRAGAAVDLGHEQVDVRKYTNN---LGIVHEMELPRVSALEVKQRRKESKRT 75
           II KYE+GHRAG   D G +    R Y NN   LGIVHE ELP ++A E KQ R+E  R 
Sbjct: 18  IIMKYEKGHRAGLPEDKGPKPF--RSYNNNVDHLGIVHETELPPLTAREAKQIRREISRK 75

Query: 76  NKWQKMLADWTKYRSTKKLSQRVYKVIPLAVRGRAWSLLLDIDRIKSQNPGKYKVMKEKG 135
           +KW  ML DW KY+S++KL  R YK +P+ +RG  WS+LL+ + +K +NPG+Y++MKEKG
Sbjct: 76  SKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEMKLKNPGRYQIMKEKG 135

Query: 136 KRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYNPEVGYHRDLSRITA 195
           K+SS  I  I  DVS TL+KH+ F  R+G KQ+EL  IL+AY  YNPEVGY RDLS I A
Sbjct: 136 KKSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAA 195

Query: 196 ILLLCLPEEDAFWALTQLLAGERHSL 221
           + LL LPEEDAFWAL QLLA ERHSL
Sbjct: 196 LFLLYLPEEDAFWALVQLLASERHSL 221


>gi|7661864 USP6 N-terminal like isoform 1 [Homo sapiens]
          Length = 828

 Score =  178 bits (452), Expect = 3e-45
 Identities = 92/205 (44%), Positives = 133/205 (64%), Gaps = 4/205 (1%)

Query: 19  IITKYEQGHRAGAAVDLGHEQVD--VRKYTNNLGIVHEMELPRVSALEVKQRRKESKRTN 76
           I+ KY++G R GA ++   E  D  V K T+  G +HE ELP  +    +Q+  E +RT 
Sbjct: 18  IVAKYDRG-REGAEIE-PWEDADYLVYKVTDRFGFLHEEELPDHNVAVERQKHLEIERTT 75

Query: 77  KWQKMLADWTKYRSTKKLSQRVYKVIPLAVRGRAWSLLLDIDRIKSQNPGKYKVMKEKGK 136
           KW KML  W KY++T+K  +R+YK IPL +RG  W+LLL+I ++K +    Y  +K + +
Sbjct: 76  KWLKMLKGWEKYKNTEKFHRRIYKGIPLQLRGEVWALLLEIPKMKEETRDLYSKLKHRAR 135

Query: 137 RSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYNPEVGYHRDLSRITAI 196
             S  I  I LDV+ T + H+MF  R+GVKQQ L  +L AYS YN EVGY + +S+ITA+
Sbjct: 136 GCSPDIRQIDLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAYSIYNTEVGYCQGMSQITAL 195

Query: 197 LLLCLPEEDAFWALTQLLAGERHSL 221
           LL+ + EEDAFWAL +L +G +H++
Sbjct: 196 LLMYMNEEDAFWALVKLFSGPKHAM 220


>gi|122937432 USP6 N-terminal like isoform 2 [Homo sapiens]
          Length = 845

 Score =  178 bits (452), Expect = 3e-45
 Identities = 92/205 (44%), Positives = 133/205 (64%), Gaps = 4/205 (1%)

Query: 19  IITKYEQGHRAGAAVDLGHEQVD--VRKYTNNLGIVHEMELPRVSALEVKQRRKESKRTN 76
           I+ KY++G R GA ++   E  D  V K T+  G +HE ELP  +    +Q+  E +RT 
Sbjct: 35  IVAKYDRG-REGAEIE-PWEDADYLVYKVTDRFGFLHEEELPDHNVAVERQKHLEIERTT 92

Query: 77  KWQKMLADWTKYRSTKKLSQRVYKVIPLAVRGRAWSLLLDIDRIKSQNPGKYKVMKEKGK 136
           KW KML  W KY++T+K  +R+YK IPL +RG  W+LLL+I ++K +    Y  +K + +
Sbjct: 93  KWLKMLKGWEKYKNTEKFHRRIYKGIPLQLRGEVWALLLEIPKMKEETRDLYSKLKHRAR 152

Query: 137 RSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYNPEVGYHRDLSRITAI 196
             S  I  I LDV+ T + H+MF  R+GVKQQ L  +L AYS YN EVGY + +S+ITA+
Sbjct: 153 GCSPDIRQIDLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAYSIYNTEVGYCQGMSQITAL 212

Query: 197 LLLCLPEEDAFWALTQLLAGERHSL 221
           LL+ + EEDAFWAL +L +G +H++
Sbjct: 213 LLMYMNEEDAFWALVKLFSGPKHAM 237


>gi|239756926 PREDICTED: similar to TBC1 domain family, member 3
           [Homo sapiens]
          Length = 424

 Score =  149 bits (375), Expect = 3e-36
 Identities = 75/149 (50%), Positives = 103/149 (69%), Gaps = 5/149 (3%)

Query: 19  IITKYEQGHRAGAAVDLGHEQVDVRKYTNNL---GIVHEMELPRVSALEVKQRRKESKRT 75
           II KYE+GHRAG   D G +      Y NN+   G+ HE ELP ++A EVKQ R+E  R 
Sbjct: 18  IIMKYEKGHRAGLPEDKGPKPFG--SYNNNIDHFGMQHETELPPLTAREVKQIRREISRK 75

Query: 76  NKWQKMLADWTKYRSTKKLSQRVYKVIPLAVRGRAWSLLLDIDRIKSQNPGKYKVMKEKG 135
           +KW KML +W  Y++++KL  R Y+ IP+ +RG  WS+LL+I+ IK +NPG+Y++MKEKG
Sbjct: 76  SKWVKMLGEWDTYKNSRKLIDRAYQGIPMNIRGPMWSVLLNIEEIKLKNPGRYQIMKEKG 135

Query: 136 KRSSRIIHCIQLDVSHTLQKHMMFIQRFG 164
           KRSS  I  + LDVS TL++H+ F  R+G
Sbjct: 136 KRSSEHIQQMDLDVSGTLRRHIFFRDRYG 164


>gi|13994322 TBC1 domain family, member 10A [Homo sapiens]
          Length = 508

 Score = 93.2 bits (230), Expect = 2e-19
 Identities = 53/143 (37%), Positives = 78/143 (54%), Gaps = 3/143 (2%)

Query: 73  KRTNKWQKMLADWTKY--RSTKKLSQRVYKVIPLAVRGRAWSLLLDIDRIKSQNPGKYKV 130
           +R +KW  ML +W K+  +  KK+  R  K IP ++RGRAW  L        QNPGK+  
Sbjct: 81  QRESKWLDMLNNWDKWMAKKHKKIRLRCQKGIPPSLRGRAWQYLSGGKVKLQQNPGKFDE 140

Query: 131 MKEKGKRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYNPEVGYHRDL 190
           + +      + +  I+ D+      H MF+ R G  QQ+L  +L AY+ Y PE GY +  
Sbjct: 141 L-DMSPGDPKWLDVIERDLHRQFPFHEMFVSRGGHGQQDLFRVLKAYTLYRPEEGYCQAQ 199

Query: 191 SRITAILLLCLPEEDAFWALTQL 213
           + I A+LL+ +P E AFW L Q+
Sbjct: 200 APIAAVLLMHMPAEQAFWCLVQI 222


>gi|167614488 TBC1 domain family, member 10B [Homo sapiens]
          Length = 808

 Score = 91.7 bits (226), Expect = 6e-19
 Identities = 50/143 (34%), Positives = 79/143 (55%), Gaps = 3/143 (2%)

Query: 73  KRTNKWQKMLADWTKYRSTK--KLSQRVYKVIPLAVRGRAWSLLLDIDRIKSQNPGKYKV 130
           +R  KW  M ++W K+ S +  K+  R  K IP ++R +AW  L +   +  QNPGK++ 
Sbjct: 330 QRELKWLDMFSNWDKWLSRRFQKVKLRCRKGIPSSLRAKAWQYLSNSKELLEQNPGKFEE 389

Query: 131 MKEKGKRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYNPEVGYHRDL 190
           + E+     + +  I+ D+      H MF  R G  QQ+L  IL AY+ Y P+ GY +  
Sbjct: 390 L-ERAPGDPKWLDVIEKDLHRQFPFHEMFAARGGHGQQDLYRILKAYTIYRPDEGYCQAQ 448

Query: 191 SRITAILLLCLPEEDAFWALTQL 213
           + + A+LL+ +P E AFW L Q+
Sbjct: 449 APVAAVLLMHMPAEQAFWCLVQI 471


>gi|38348348 TBC1 domain family, member 10C [Homo sapiens]
          Length = 446

 Score = 85.5 bits (210), Expect = 4e-17
 Identities = 50/143 (34%), Positives = 72/143 (50%), Gaps = 3/143 (2%)

Query: 73  KRTNKWQKMLADWTKYRST--KKLSQRVYKVIPLAVRGRAWSLLLDIDRIKSQNPGKYKV 130
           +R  KW +M + W K  S   KK+  +  K IP A+R R W LL      +  +PG Y+ 
Sbjct: 62  QREMKWVEMTSHWEKTMSRRYKKVKMQCRKGIPSALRARCWPLLCGAHVCQKNSPGTYQE 121

Query: 131 MKEKGKRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYNPEVGYHRDL 190
           + E      + +  I  D+      H MF+   G  QQ L  +L AY+ Y PE GY +  
Sbjct: 122 LAE-APGDPQWMETIGRDLHRQFPLHEMFVSPQGHGQQGLLQVLKAYTLYRPEQGYCQAQ 180

Query: 191 SRITAILLLCLPEEDAFWALTQL 213
             + A+LL+ LP E+AFW L Q+
Sbjct: 181 GPVAAVLLMHLPPEEAFWCLVQI 203


>gi|139394668 TBC1 domain family, member 9 (with GRAM domain) [Homo
           sapiens]
          Length = 1266

 Score = 71.2 bits (173), Expect = 8e-13
 Identities = 48/149 (32%), Positives = 77/149 (51%), Gaps = 8/149 (5%)

Query: 70  KESKRTNKWQKMLADWTK----YRSTKKLSQRVYKVIPLAVRGRAWSLLLDIDRIKSQNP 125
           KE  +   W+   A++ +    YR T+K  + V K IP ++RG  W LL      K+ +P
Sbjct: 481 KEFLKEQAWKIHFAEYGQGICMYR-TEKTRELVLKGIPESMRGELWLLLSGAINEKATHP 539

Query: 126 GKYKVMKEKGKRSSRII-HCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYNPEV 184
           G Y+ + EK      +    I+ D+  +L +H  F    G+    L  +L AY+  NP +
Sbjct: 540 GYYEDLVEKSMGKYNLATEEIERDLHRSLPEHPAFQNEMGIAA--LRRVLTAYAFRNPNI 597

Query: 185 GYHRDLSRITAILLLCLPEEDAFWALTQL 213
           GY + ++ +T++LLL   EE+AFW L  L
Sbjct: 598 GYCQAMNIVTSVLLLYAKEEEAFWLLVAL 626


>gi|50658061 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
           [Homo sapiens]
          Length = 1168

 Score = 69.3 bits (168), Expect = 3e-12
 Identities = 49/147 (33%), Positives = 72/147 (48%), Gaps = 7/147 (4%)

Query: 75  TNKWQKMLADWTKYR---STKKLSQRVYKVIPLAVRGRAWSLLLDIDRIKSQNPGKYKVM 131
           T  W+KML+   + +     +K+   V + +P   RG  W  L +   +K Q P K +  
Sbjct: 771 TTVWEKMLSTPGRSKIKFDMEKMHSAVGQGVPRHHRGEIWKFLAEQFHLKHQFPSKQQPK 830

Query: 132 ----KEKGKRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYNPEVGYH 187
               KE  K+ +   H I +D+  T   H  F  + G  Q  L +IL AYS  + EVGY 
Sbjct: 831 DVPYKELLKQLTSQQHAILIDLGRTFPTHPYFSAQLGAGQLSLYNILKAYSLLDQEVGYC 890

Query: 188 RDLSRITAILLLCLPEEDAFWALTQLL 214
           + LS +  ILLL + EE+AF  L  L+
Sbjct: 891 QGLSFVAGILLLHMSEEEAFKMLKFLM 917


>gi|148806902 TBC1 domain family, member 12 [Homo sapiens]
          Length = 775

 Score = 67.4 bits (163), Expect = 1e-11
 Identities = 62/234 (26%), Positives = 100/234 (42%), Gaps = 39/234 (16%)

Query: 3   MDGDPYNLPAQGQGNIIITKYEQGHRAGAAVDLGHEQVDVRKYTNNLGIVHEMELPRVSA 62
           ++  P NLPA+     +  + E       A     ++   RK              R+  
Sbjct: 399 LEDRPSNLPAKSVEEALRHRQEYDEMVAEAKKREIKEAHKRK--------------RIMK 444

Query: 63  LEVKQRRKESKRTNKW-QKMLADWTKYRSTKKLSQRVYKVIPLAVRGRAWSLLLDIDRIK 121
              KQ    +     W  ++L +W   RST+++ +  ++ +P +VRG+ WSL +  +   
Sbjct: 445 ERFKQEENIASAMVIWINEILPNWEVMRSTRRVRELWWQGLPPSVRGKVWSLAVGNEL-- 502

Query: 122 SQNPGKYKVM----KEKGKRSSRI-----------------IHCIQLDVSHTLQKHMMFI 160
           +  P  Y++     KE+ K  S                   +  I+LD+S T     +F 
Sbjct: 503 NITPELYEIFLSRAKERWKSFSETSSENDTEGVSVADREASLELIKLDISRTFPSLYIF- 561

Query: 161 QRFGVKQQELCDILVAYSAYNPEVGYHRDLSRITAILLLCLPEEDAFWALTQLL 214
           Q+ G     L  IL AY+ Y P+VGY + +S I A+L+L L E DAF A   LL
Sbjct: 562 QKGGPYHDVLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLEEADAFIAFANLL 615


>gi|156231067 TBC1 domain family, member 8 [Homo sapiens]
          Length = 1140

 Score = 65.9 bits (159), Expect = 3e-11
 Identities = 39/121 (32%), Positives = 67/121 (55%), Gaps = 3/121 (2%)

Query: 91  TKKLSQRVYKVIPLAVRGRAWSLLLDIDRIKSQNPGKY-KVMKEKGKRSSRIIHCIQLDV 149
           T+K+ + V   IP ++RGR W L  D     + +PG Y  +++E   +   +   I+ D+
Sbjct: 495 TEKIRKLVAMGIPESLRGRLWLLFSDAVTDLASHPGYYGNLVEESLGKCCLVTEEIERDL 554

Query: 150 SHTLQKHMMFIQRFGVKQQELCDILVAYSAYNPEVGYHRDLSRITAILLLCLPEEDAFWA 209
             +L +H  F    G+    L  +L AY+  NP++GY + ++ +T++LLL   EE+AFW 
Sbjct: 555 HRSLPEHPAFQNETGIAA--LRRVLTAYAHRNPKIGYCQSMNILTSVLLLYTKEEEAFWL 612

Query: 210 L 210
           L
Sbjct: 613 L 613


>gi|38570103 TBC1 domain family, member 8B (with GRAM domain)
           isoform b [Homo sapiens]
          Length = 632

 Score = 65.1 bits (157), Expect = 6e-11
 Identities = 46/164 (28%), Positives = 80/164 (48%), Gaps = 10/164 (6%)

Query: 51  IVHEMELPRVSALEVKQRRKESKRTNKWQKMLADWTKYRS---TKKLSQRVYKVIPLAVR 107
           + H   L  +++  +K++ KE      W+ + A+  +  S   TKK    V + IP  +R
Sbjct: 438 VFHPQNLETLNSKMLKEKMKEQS----WKILFAECGRGVSMFRTKKTRDLVVRGIPETLR 493

Query: 108 GRAWSLLLDIDRIKSQNPGKYKVMKEKGKRSSRII-HCIQLDVSHTLQKHMMFIQRFGVK 166
           G  W L        + NP  Y  + E+   +  +    I+ D+  +L +H  F    G+ 
Sbjct: 494 GELWMLFSGAVNDMATNPDYYTEVVEQSLGTCNLATEEIERDLRRSLPEHPAFQSDTGIS 553

Query: 167 QQELCDILVAYSAYNPEVGYHRDLSRITAILLLCLPEEDAFWAL 210
              L  +L AY+  NP++GY + ++ +T++LLL   EE+AFW L
Sbjct: 554 A--LRRVLTAYAYRNPKIGYCQAMNILTSVLLLYAKEEEAFWLL 595


>gi|38570101 TBC1 domain family, member 8B (with GRAM domain)
           isoform a [Homo sapiens]
          Length = 1120

 Score = 65.1 bits (157), Expect = 6e-11
 Identities = 46/164 (28%), Positives = 80/164 (48%), Gaps = 10/164 (6%)

Query: 51  IVHEMELPRVSALEVKQRRKESKRTNKWQKMLADWTKYRS---TKKLSQRVYKVIPLAVR 107
           + H   L  +++  +K++ KE      W+ + A+  +  S   TKK    V + IP  +R
Sbjct: 438 VFHPQNLETLNSKMLKEKMKEQS----WKILFAECGRGVSMFRTKKTRDLVVRGIPETLR 493

Query: 108 GRAWSLLLDIDRIKSQNPGKYKVMKEKGKRSSRII-HCIQLDVSHTLQKHMMFIQRFGVK 166
           G  W L        + NP  Y  + E+   +  +    I+ D+  +L +H  F    G+ 
Sbjct: 494 GELWMLFSGAVNDMATNPDYYTEVVEQSLGTCNLATEEIERDLRRSLPEHPAFQSDTGIS 553

Query: 167 QQELCDILVAYSAYNPEVGYHRDLSRITAILLLCLPEEDAFWAL 210
              L  +L AY+  NP++GY + ++ +T++LLL   EE+AFW L
Sbjct: 554 A--LRRVLTAYAYRNPKIGYCQAMNILTSVLLLYAKEEEAFWLL 595


>gi|164519084 RAB GTPase activating protein 1 [Homo sapiens]
          Length = 1069

 Score = 64.7 bits (156), Expect = 7e-11
 Identities = 46/141 (32%), Positives = 69/141 (48%), Gaps = 10/141 (7%)

Query: 78  WQKMLADWTKYRST--KKLSQRVYKVIPLAVRGRAWSLLLDIDRIKSQNPGKYKVM--KE 133
           W ++L+ W    +   K+LS  V   +P A+RG  W LL            KY+++  KE
Sbjct: 541 WGELLSKWHLNLNVRPKQLSSLVRNGVPEALRGEVWQLLAGCHN-NDHLVEKYRILITKE 599

Query: 134 KGKRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYNPEVGYHRDLSRI 193
             + S+     I  D++ T   H  F    G  Q  L  I  AYS Y+ E+GY +  S +
Sbjct: 600 SPQDSA-----ITRDINRTFPAHDYFKDTGGDGQDSLYKICKAYSVYDEEIGYCQGQSFL 654

Query: 194 TAILLLCLPEEDAFWALTQLL 214
            A+LLL +PEE AF  L +++
Sbjct: 655 AAVLLLHMPEEQAFSVLVKIM 675


>gi|118722351 growth hormone regulated TBC protein 1 [Homo sapiens]
          Length = 336

 Score = 64.7 bits (156), Expect = 7e-11
 Identities = 48/159 (30%), Positives = 81/159 (50%), Gaps = 5/159 (3%)

Query: 72  SKRTNKWQKMLADWTKYRSTKKLSQRVYKVIPLAVRGRAWSLLLDIDRIKSQNPGKYKVM 131
           ++R  KW ++L      RS + + + V K +PL  R R W +L        QNPG Y  +
Sbjct: 40  TRRAIKWSRLLQGGGVPRS-RTVKRYVRKGVPLEHRARVWMVLSGAQAQMDQNPGYYHQL 98

Query: 132 KEKGKRSSRIIHCIQLDVSHTLQKHMMFIQRFG-VKQQELCDILVAYSAYNPEVGYHRDL 190
            + G+R+ R+   I+ D++ T   ++ F +      Q+ L ++L+AY  +N  VGY + +
Sbjct: 99  LQ-GERNPRLEDAIRTDLNRTFPDNVKFRKTTDPCLQRTLYNVLLAYGHHNQGVGYCQGM 157

Query: 191 SRITAILLLCL-PEEDAFWALTQLLAGERHSLWYSTAQI 228
           + I   L+L    EE++FW L   L G     +YS A +
Sbjct: 158 NFIAGYLILITNNEEESFW-LLDALVGRILPDYYSPAML 195


>gi|164565381 TBC1 domain family, member 14 isoform b [Homo sapiens]
          Length = 413

 Score = 62.4 bits (150), Expect = 4e-10
 Identities = 57/180 (31%), Positives = 86/180 (47%), Gaps = 25/180 (13%)

Query: 59  RVSALEVKQRRKES--KRTNKWQ-KMLADWTKYRSTKKLSQRVYKVIPLAVRGRAWSL-- 113
           R   LE + R +ES       W  ++L +W     ++K+    ++ IP +VRG+ WSL  
Sbjct: 76  RKKQLEERCRVEESIGNAVLTWNNEILPNWETMWCSRKVRDLWWQGIPPSVRGKVWSLAI 135

Query: 114 ---------LLDI------DRIKSQNPGKYKVMKEKGKRSSR----IIHCIQLDVSHTLQ 154
                    L DI      +R +S + G  +V  E    S+      +  I+LD+S T  
Sbjct: 136 GNELNITHELFDICLARAKERWRSLSTGGSEVENEDAGFSAADREASLELIKLDISRTFP 195

Query: 155 KHMMFIQRFGVKQQELCDILVAYSAYNPEVGYHRDLSRITAILLLCLPEEDAFWALTQLL 214
              +F Q+ G     L  IL AY+ Y P+VGY + +S I A+L+L L   DAF A + LL
Sbjct: 196 NLCIF-QQGGPYHDMLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLL 254


>gi|164565368 TBC1 domain family, member 14 isoform a [Homo sapiens]
          Length = 693

 Score = 62.4 bits (150), Expect = 4e-10
 Identities = 57/180 (31%), Positives = 86/180 (47%), Gaps = 25/180 (13%)

Query: 59  RVSALEVKQRRKES--KRTNKWQ-KMLADWTKYRSTKKLSQRVYKVIPLAVRGRAWSL-- 113
           R   LE + R +ES       W  ++L +W     ++K+    ++ IP +VRG+ WSL  
Sbjct: 356 RKKQLEERCRVEESIGNAVLTWNNEILPNWETMWCSRKVRDLWWQGIPPSVRGKVWSLAI 415

Query: 114 ---------LLDI------DRIKSQNPGKYKVMKEKGKRSSR----IIHCIQLDVSHTLQ 154
                    L DI      +R +S + G  +V  E    S+      +  I+LD+S T  
Sbjct: 416 GNELNITHELFDICLARAKERWRSLSTGGSEVENEDAGFSAADREASLELIKLDISRTFP 475

Query: 155 KHMMFIQRFGVKQQELCDILVAYSAYNPEVGYHRDLSRITAILLLCLPEEDAFWALTQLL 214
              +F Q+ G     L  IL AY+ Y P+VGY + +S I A+L+L L   DAF A + LL
Sbjct: 476 NLCIF-QQGGPYHDMLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLL 534


>gi|164565366 TBC1 domain family, member 14 isoform a [Homo sapiens]
          Length = 693

 Score = 62.4 bits (150), Expect = 4e-10
 Identities = 57/180 (31%), Positives = 86/180 (47%), Gaps = 25/180 (13%)

Query: 59  RVSALEVKQRRKES--KRTNKWQ-KMLADWTKYRSTKKLSQRVYKVIPLAVRGRAWSL-- 113
           R   LE + R +ES       W  ++L +W     ++K+    ++ IP +VRG+ WSL  
Sbjct: 356 RKKQLEERCRVEESIGNAVLTWNNEILPNWETMWCSRKVRDLWWQGIPPSVRGKVWSLAI 415

Query: 114 ---------LLDI------DRIKSQNPGKYKVMKEKGKRSSR----IIHCIQLDVSHTLQ 154
                    L DI      +R +S + G  +V  E    S+      +  I+LD+S T  
Sbjct: 416 GNELNITHELFDICLARAKERWRSLSTGGSEVENEDAGFSAADREASLELIKLDISRTFP 475

Query: 155 KHMMFIQRFGVKQQELCDILVAYSAYNPEVGYHRDLSRITAILLLCLPEEDAFWALTQLL 214
              +F Q+ G     L  IL AY+ Y P+VGY + +S I A+L+L L   DAF A + LL
Sbjct: 476 NLCIF-QQGGPYHDMLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLL 534


>gi|45597177 TBC1 domain family, member 9B (with GRAM domain)
           isoform b [Homo sapiens]
          Length = 1233

 Score = 61.6 bits (148), Expect = 6e-10
 Identities = 45/149 (30%), Positives = 70/149 (46%), Gaps = 8/149 (5%)

Query: 70  KESKRTNKWQKMLADWTK----YRSTKKLSQRVYKVIPLAVRGRAWSLLLDIDRIKSQNP 125
           KE  +   W     ++ +    YR T K    V K IP ++RG  W L          +P
Sbjct: 474 KEKMKEESWHIHFFEYGRGVCMYR-TAKTRALVLKGIPESLRGELWLLFSGAWNEMVTHP 532

Query: 126 GKYKVMKEKGK-RSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYNPEV 184
           G Y  + EK   + S     I+ D+  ++ +H  F    G+    L  +L AY+  NP +
Sbjct: 533 GYYAELVEKSTGKYSLATEEIERDLHRSMPEHPAFQNELGIAA--LRRVLTAYAFRNPTI 590

Query: 185 GYHRDLSRITAILLLCLPEEDAFWALTQL 213
           GY + ++ +T++LLL   EE+AFW L  L
Sbjct: 591 GYCQAMNIVTSVLLLYGSEEEAFWLLVAL 619


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.134    0.403 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,727,946
Number of Sequences: 37866
Number of extensions: 397360
Number of successful extensions: 895
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 49
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 808
Number of HSP's gapped (non-prelim): 67
length of query: 250
length of database: 18,247,518
effective HSP length: 100
effective length of query: 150
effective length of database: 14,460,918
effective search space: 2169137700
effective search space used: 2169137700
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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