Search of human proteins with 147904948

Search of human proteins with 147904948

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|147904948 calcium channel, voltage-dependent, beta 2 subunit
isoform 8 [Homo sapiens]
         (608 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|147904948 calcium channel, voltage-dependent, beta 2 subunit ...  1217   0.0  
gi|45359842 calcium channel, voltage-dependent, beta 2 subunit i...  1194   0.0  
gi|148223541 calcium channel, voltage-dependent, beta 2 subunit ...  1155   0.0  
gi|147901383 calcium channel, voltage-dependent, beta 2 subunit ...  1139   0.0  
gi|147898681 calcium channel, voltage-dependent, beta 2 subunit ...  1133   0.0  
gi|148232726 calcium channel, voltage-dependent, beta 2 subunit ...  1073   0.0  
gi|45359834 calcium channel, voltage-dependent, beta 2 subunit i...  1072   0.0  
gi|148226485 calcium channel, voltage-dependent, beta 2 subunit ...  1072   0.0  
gi|40804468 calcium channel, voltage-dependent, beta 1 subunit i...   731   0.0  
gi|40804472 calcium channel, voltage-dependent, beta 1 subunit i...   674   0.0  
gi|40804470 calcium channel, voltage-dependent, beta 1 subunit i...   667   0.0  
gi|54607066 calcium channel, voltage-dependent, beta 4 subunit i...   636   0.0  
gi|54607064 calcium channel, voltage-dependent, beta 4 subunit i...   636   0.0  
gi|54607068 calcium channel, voltage-dependent, beta 4 subunit i...   619   e-177
gi|224831262 calcium channel, voltage-dependent, beta 4 subunit ...   539   e-153
gi|40316928 calcium channel, voltage-dependent, beta 3 subunit [...   537   e-152
gi|50962882 G patch domain containing 8 [Homo sapiens]                 58   3e-08
gi|119943106 synapse-associated protein 102 isoform a [Homo sapi...    52   1e-06
gi|148539628 discs, large homolog 1 isoform 1 [Homo sapiens]           51   4e-06
gi|148539578 discs, large homolog 1 isoform 2 [Homo sapiens]           50   5e-06
gi|4504487 histidine rich calcium binding protein precursor [Hom...    50   5e-06
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        49   2e-05
gi|218156338 chapsyn-110 isoform 1 [Homo sapiens]                      48   3e-05
gi|91199538 chapsyn-110 isoform 2 [Homo sapiens]                       48   3e-05
gi|9945320 cyclin L1 [Homo sapiens]                                    48   3e-05
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s...    47   4e-05
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ...    46   1e-04
gi|14149807 coiled-coil domain containing 55 isoform 1 [Homo sap...    45   1e-04
gi|23111062 splicing factor, arginine/serine-rich 8 [Homo sapiens]     45   2e-04
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]          44   4e-04

>gi|147904948 calcium channel, voltage-dependent, beta 2 subunit
           isoform 8 [Homo sapiens]
          Length = 608

 Score = 1217 bits (3148), Expect = 0.0
 Identities = 608/608 (100%), Positives = 608/608 (100%)

Query: 1   MNQGSGLDLLKISYGKGARRKNRFKGSDGSTSSDTTSNSFVRQGSADSYTSRPSDSDVSL 60
           MNQGSGLDLLKISYGKGARRKNRFKGSDGSTSSDTTSNSFVRQGSADSYTSRPSDSDVSL
Sbjct: 1   MNQGSGLDLLKISYGKGARRKNRFKGSDGSTSSDTTSNSFVRQGSADSYTSRPSDSDVSL 60

Query: 61  EEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFL 120
           EEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFL
Sbjct: 61  EEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFL 120

Query: 121 HVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSL 180
           HVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSL
Sbjct: 121 HVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSL 180

Query: 181 GDIVPSSRKSTPPSSGAKSADEQDQWKTAGLFWRFTTEHTPPYDVVPSMRPVVLVGPSLK 240
           GDIVPSSRKSTPPSSGAKSADEQDQWKTAGLFWRFTTEHTPPYDVVPSMRPVVLVGPSLK
Sbjct: 181 GDIVPSSRKSTPPSSGAKSADEQDQWKTAGLFWRFTTEHTPPYDVVPSMRPVVLVGPSLK 240

Query: 241 GYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLA 300
           GYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLA
Sbjct: 241 GYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLA 300

Query: 301 EVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRG 360
           EVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRG
Sbjct: 301 EVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRG 360

Query: 361 KSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLP 420
           KSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLP
Sbjct: 361 KSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLP 420

Query: 421 NPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRS 480
           NPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRS
Sbjct: 421 NPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRS 480

Query: 481 SSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRD 540
           SSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRD
Sbjct: 481 SSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRD 540

Query: 541 ETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEW 600
           ETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEW
Sbjct: 541 ETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEW 600

Query: 601 NRDVYIRQ 608
           NRDVYIRQ
Sbjct: 601 NRDVYIRQ 608


>gi|45359842 calcium channel, voltage-dependent, beta 2 subunit
           isoform 4 [Homo sapiens]
          Length = 636

 Score = 1194 bits (3089), Expect = 0.0
 Identities = 596/596 (100%), Positives = 596/596 (100%)

Query: 13  SYGKGARRKNRFKGSDGSTSSDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRREAE 72
           SYGKGARRKNRFKGSDGSTSSDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRREAE
Sbjct: 41  SYGKGARRKNRFKGSDGSTSSDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRREAE 100

Query: 73  RQAQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWI 132
           RQAQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWI
Sbjct: 101 RQAQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWI 160

Query: 133 GRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTP 192
           GRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTP
Sbjct: 161 GRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTP 220

Query: 193 PSSGAKSADEQDQWKTAGLFWRFTTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKAL 252
           PSSGAKSADEQDQWKTAGLFWRFTTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKAL
Sbjct: 221 PSSGAKSADEQDQWKTAGLFWRFTTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKAL 280

Query: 253 FDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFEL 312
           FDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFEL
Sbjct: 281 FDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFEL 340

Query: 313 ARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMV 372
           ARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMV
Sbjct: 341 ARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMV 400

Query: 373 AADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSS 432
           AADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSS
Sbjct: 401 AADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSS 460

Query: 433 LPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSG 492
           LPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSG
Sbjct: 461 LPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSG 520

Query: 493 TSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRE 552
           TSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRE
Sbjct: 521 TSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRE 580

Query: 553 SRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ 608
           SRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ
Sbjct: 581 SRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ 636


>gi|148223541 calcium channel, voltage-dependent, beta 2 subunit
           isoform 6 [Homo sapiens]
          Length = 632

 Score = 1155 bits (2989), Expect = 0.0
 Identities = 591/632 (93%), Positives = 594/632 (93%), Gaps = 24/632 (3%)

Query: 1   MNQGSGLDLLKISYGKGARRKNRFKGSDGSTSSDTTSNSFVRQGSADSYTSRPSDSDVSL 60
           MNQGSGLDLLKISYGKGARRKNRFKGSDGSTSSDTTSNSFVRQGSADSYTSRPSDSDVSL
Sbjct: 1   MNQGSGLDLLKISYGKGARRKNRFKGSDGSTSSDTTSNSFVRQGSADSYTSRPSDSDVSL 60

Query: 61  EEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFL 120
           EEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFL
Sbjct: 61  EEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFL 120

Query: 121 HVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSL 180
           HVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSL
Sbjct: 121 HVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSL 180

Query: 181 GDIVPSSRKSTPPSSGAK------SADEQD------------------QWKTAGLFWRFT 216
           GDIVPSSRKSTPPSS          A+E D                    K   + +   
Sbjct: 181 GDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKPSANSVTSPHSKEKRMPFFKK 240

Query: 217 TEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLA 276
           TEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLA
Sbjct: 241 TEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLA 300

Query: 277 KRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTS 336
           KRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTS
Sbjct: 301 KRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTS 360

Query: 337 LAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLED 396
           LAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLED
Sbjct: 361 LAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLED 420

Query: 397 ACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSA 456
           ACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSA
Sbjct: 421 ACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSA 480

Query: 457 PIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYV 516
           PIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYV
Sbjct: 481 PIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYV 540

Query: 517 EPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRH 576
           EPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRH
Sbjct: 541 EPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRH 600

Query: 577 KSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ 608
           KSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ
Sbjct: 601 KSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ 632


>gi|147901383 calcium channel, voltage-dependent, beta 2 subunit
           isoform 5 [Homo sapiens]
          Length = 622

 Score = 1139 bits (2945), Expect = 0.0
 Identities = 575/596 (96%), Positives = 577/596 (96%), Gaps = 14/596 (2%)

Query: 13  SYGKGARRKNRFKGSDGSTSSDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRREAE 72
           SYGKGARRKNRFKGSDGSTSSDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRREAE
Sbjct: 41  SYGKGARRKNRFKGSDGSTSSDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRREAE 100

Query: 73  RQAQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWI 132
           RQAQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWI
Sbjct: 101 RQAQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWI 160

Query: 133 GRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTP 192
           GRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTP
Sbjct: 161 GRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTP 220

Query: 193 PSSGAKSADEQDQWKTAGLFWRFTTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKAL 252
           PSS  +                 +TEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKAL
Sbjct: 221 PSSAKQKQK--------------STEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKAL 266

Query: 253 FDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFEL 312
           FDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFEL
Sbjct: 267 FDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFEL 326

Query: 313 ARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMV 372
           ARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMV
Sbjct: 327 ARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMV 386

Query: 373 AADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSS 432
           AADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSS
Sbjct: 387 AADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSS 446

Query: 433 LPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSG 492
           LPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSG
Sbjct: 447 LPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSG 506

Query: 493 TSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRE 552
           TSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRE
Sbjct: 507 TSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRE 566

Query: 553 SRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ 608
           SRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ
Sbjct: 567 SRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ 622


>gi|147898681 calcium channel, voltage-dependent, beta 2 subunit
           isoform 2 [Homo sapiens]
          Length = 660

 Score = 1133 bits (2930), Expect = 0.0
 Identities = 579/620 (93%), Positives = 582/620 (93%), Gaps = 24/620 (3%)

Query: 13  SYGKGARRKNRFKGSDGSTSSDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRREAE 72
           SYGKGARRKNRFKGSDGSTSSDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRREAE
Sbjct: 41  SYGKGARRKNRFKGSDGSTSSDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRREAE 100

Query: 73  RQAQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWI 132
           RQAQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWI
Sbjct: 101 RQAQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWI 160

Query: 133 GRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTP 192
           GRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTP
Sbjct: 161 GRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTP 220

Query: 193 PSSGAK------SADEQD------------------QWKTAGLFWRFTTEHTPPYDVVPS 228
           PSS          A+E D                    K   + +   TEHTPPYDVVPS
Sbjct: 221 PSSAIDIDATGLDAEENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPS 280

Query: 229 MRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHA 288
           MRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHA
Sbjct: 281 MRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHA 340

Query: 289 IIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISS 348
           IIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISS
Sbjct: 341 IIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISS 400

Query: 349 PKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAY 408
           PKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAY
Sbjct: 401 PKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAY 460

Query: 409 WKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEP 468
           WKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEP
Sbjct: 461 WKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEP 520

Query: 469 SVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVD 528
           SVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVD
Sbjct: 521 SVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVD 580

Query: 529 HYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGE 588
           HYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGE
Sbjct: 581 HYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGE 640

Query: 589 VISKKRNEAGEWNRDVYIRQ 608
           VISKKRNEAGEWNRDVYIRQ
Sbjct: 641 VISKKRNEAGEWNRDVYIRQ 660


>gi|148232726 calcium channel, voltage-dependent, beta 2 subunit
           isoform 1 [Homo sapiens]
          Length = 605

 Score = 1073 bits (2774), Expect = 0.0
 Identities = 549/592 (92%), Positives = 552/592 (93%), Gaps = 24/592 (4%)

Query: 41  VRQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAA 100
           V  GSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAA
Sbjct: 14  VSYGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAA 73

Query: 101 HEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQ 160
           HEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQ
Sbjct: 74  HEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQ 133

Query: 161 RAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSGAK------SADEQD---------- 204
           RAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSS          A+E D          
Sbjct: 134 RAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKP 193

Query: 205 --------QWKTAGLFWRFTTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFL 256
                     K   + +   TEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFL
Sbjct: 194 SANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFL 253

Query: 257 KHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTL 316
           KHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTL
Sbjct: 254 KHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTL 313

Query: 317 QLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADK 376
           QLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADK
Sbjct: 314 QLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADK 373

Query: 377 LAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLS 436
           LAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLS
Sbjct: 374 LAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLS 433

Query: 437 PTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRG 496
           PTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRG
Sbjct: 434 PTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRG 493

Query: 497 LSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHR 556
           LSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHR
Sbjct: 494 LSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHR 553

Query: 557 SRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ 608
           SRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ
Sbjct: 554 SRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ 605


>gi|45359834 calcium channel, voltage-dependent, beta 2 subunit
           isoform 7 [Homo sapiens]
          Length = 612

 Score = 1072 bits (2772), Expect = 0.0
 Identities = 548/589 (93%), Positives = 551/589 (93%), Gaps = 24/589 (4%)

Query: 44  GSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHED 103
           GSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHED
Sbjct: 24  GSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHED 83

Query: 104 DVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAK 163
           DVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAK
Sbjct: 84  DVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAK 143

Query: 164 QGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSGAK------SADEQD------------- 204
           QGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSS          A+E D             
Sbjct: 144 QGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKPSAN 203

Query: 205 -----QWKTAGLFWRFTTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR 259
                  K   + +   TEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR
Sbjct: 204 SVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR 263

Query: 260 FEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLV 319
           FEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLV
Sbjct: 264 FEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLV 323

Query: 320 VLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQ 379
           VLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQ
Sbjct: 324 VLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQ 383

Query: 380 CPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTL 439
           CPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTL
Sbjct: 384 CPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTL 443

Query: 440 ASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSR 499
           ASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSR
Sbjct: 444 ASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSR 503

Query: 500 QETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRD 559
           QETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRD
Sbjct: 504 QETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRD 563

Query: 560 VDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ 608
           VDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ
Sbjct: 564 VDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ 612


>gi|148226485 calcium channel, voltage-dependent, beta 2 subunit
           isoform 3 [Homo sapiens]
          Length = 606

 Score = 1072 bits (2772), Expect = 0.0
 Identities = 548/589 (93%), Positives = 551/589 (93%), Gaps = 24/589 (4%)

Query: 44  GSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHED 103
           GSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHED
Sbjct: 18  GSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHED 77

Query: 104 DVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAK 163
           DVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAK
Sbjct: 78  DVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAK 137

Query: 164 QGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSGAK------SADEQD------------- 204
           QGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSS          A+E D             
Sbjct: 138 QGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKPSAN 197

Query: 205 -----QWKTAGLFWRFTTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR 259
                  K   + +   TEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR
Sbjct: 198 SVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR 257

Query: 260 FEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLV 319
           FEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLV
Sbjct: 258 FEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLV 317

Query: 320 VLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQ 379
           VLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQ
Sbjct: 318 VLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQ 377

Query: 380 CPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTL 439
           CPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTL
Sbjct: 378 CPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTL 437

Query: 440 ASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSR 499
           ASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSR
Sbjct: 438 ASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSR 497

Query: 500 QETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRD 559
           QETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRD
Sbjct: 498 QETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRD 557

Query: 560 VDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ 608
           VDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ
Sbjct: 558 VDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ 606


>gi|40804468 calcium channel, voltage-dependent, beta 1 subunit
           isoform 1 [Homo sapiens]
          Length = 598

 Score =  731 bits (1886), Expect = 0.0
 Identities = 389/597 (65%), Positives = 452/597 (75%), Gaps = 31/597 (5%)

Query: 15  GKGARRKNRFKGSDGSTSSDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRREAERQ 74
           GK ++RK RFK SDGSTSSDTTSNSFVRQGSA+SYTSRPSDSDVSLEEDREA+R+EAERQ
Sbjct: 29  GKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSAESYTSRPSDSDVSLEEDREALRKEAERQ 88

Query: 75  AQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGR 134
           A AQLEKAKTKPVAFAVRTNV Y+ +  D+VPV G+AI+FE KDFLH+KEK+NNDWWIGR
Sbjct: 89  ALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGR 148

Query: 135 LVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPS 194
           LVKEGCE+GFIPSPVKL+++RL  EQ+ +Q +  SSKSG NSSSSLGD+V  +R+ TPP+
Sbjct: 149 LVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNRLGSSKSGDNSSSSLGDVVTGTRRPTPPA 208

Query: 195 SGAKSADEQDQWKTAGLFWRFTTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFD 254
           S  +                 +TEH PPYDVVPSMRP++LVGPSLKGYEVTDMMQKALFD
Sbjct: 209 SAKQKQK--------------STEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFD 254

Query: 255 FLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELAR 314
           FLKHRF+GRISITRVTADISLAKRSVLNNPSKH IIERSNTRSSLAEVQSEIERIFELAR
Sbjct: 255 FLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELAR 314

Query: 315 TLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAA 374
           TLQLV LDADTINHPAQLSKTSLAPIIVY+KI+SPKVLQRLIKSRGKSQ+KHLNVQ+ A+
Sbjct: 315 TLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAAS 374

Query: 375 DKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLP 434
           +KLAQCPPE+FD+ILDENQLEDACEHLA+YLEAYWKATHPPSS+ PNPLL+RT+AT++L 
Sbjct: 375 EKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALA 434

Query: 435 LSPTLASNSQG---SQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRS 491
            SP   SN QG   + GDQ      P+  A+         P +  Q      + H   R+
Sbjct: 435 ASPAPVSNLQGPYLASGDQ------PLERATGEHASMHEYPGELGQPPGLYPSSHPPGRA 488

Query: 492 GTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHR 551
           GT R LSRQ+TFD++T  SR+SAY E         VD      +     +  G      R
Sbjct: 489 GTLRALSRQDTFDADTPGSRNSAYTE----LGDSCVDMETDPSEGPGLGDPAGGGTPPAR 544

Query: 552 ESRHRSRDVDREQDHNECNKQRSRHKSKDRYC-EKDGEVISKKRNEAGEWNRDVYIR 607
           +      + D E+   E    R+R ++K RYC E  G V+ + +NE   W R VYIR
Sbjct: 545 QGSWEDEEEDYEE---ELTDNRNRGRNKARYCAEGGGPVLGRNKNELEGWGRGVYIR 598


>gi|40804472 calcium channel, voltage-dependent, beta 1 subunit
           isoform 3 [Homo sapiens]
          Length = 478

 Score =  674 bits (1738), Expect = 0.0
 Identities = 338/430 (78%), Positives = 380/430 (88%), Gaps = 14/430 (3%)

Query: 15  GKGARRKNRFKGSDGSTSSDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRREAERQ 74
           GK ++RK RFK SDGSTSSDTTSNSFVRQGSA+SYTSRPSDSDVSLEEDREA+R+EAERQ
Sbjct: 29  GKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSAESYTSRPSDSDVSLEEDREALRKEAERQ 88

Query: 75  AQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGR 134
           A AQLEKAKTKPVAFAVRTNV Y+ +  D+VPV G+AI+FE KDFLH+KEK+NNDWWIGR
Sbjct: 89  ALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGR 148

Query: 135 LVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPS 194
           LVKEGCE+GFIPSPVKL+++RL  EQ+ +Q +  SSKSG NSSSSLGD+V  +R+ TPP+
Sbjct: 149 LVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNRLGSSKSGDNSSSSLGDVVTGTRRPTPPA 208

Query: 195 SGAKSADEQDQWKTAGLFWRFTTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFD 254
           S  +                 +TEH PPYDVVPSMRP++LVGPSLKGYEVTDMMQKALFD
Sbjct: 209 SAKQKQK--------------STEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFD 254

Query: 255 FLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELAR 314
           FLKHRF+GRISITRVTADISLAKRSVLNNPSKH IIERSNTRSSLAEVQSEIERIFELAR
Sbjct: 255 FLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELAR 314

Query: 315 TLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAA 374
           TLQLV LDADTINHPAQLSKTSLAPIIVY+KI+SPKVLQRLIKSRGKSQ+KHLNVQ+ A+
Sbjct: 315 TLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAAS 374

Query: 375 DKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLP 434
           +KLAQCPPE+FD+ILDENQLEDACEHLA+YLEAYWKATHPPSS+ PNPLL+RT+AT++L 
Sbjct: 375 EKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALA 434

Query: 435 LSPTLASNSQ 444
            SP   SN Q
Sbjct: 435 ASPAPVSNLQ 444


>gi|40804470 calcium channel, voltage-dependent, beta 1 subunit
           isoform 2 [Homo sapiens]
          Length = 523

 Score =  667 bits (1721), Expect = 0.0
 Identities = 343/462 (74%), Positives = 389/462 (84%), Gaps = 33/462 (7%)

Query: 15  GKGARRKNRFKGSDGSTSSDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRREAERQ 74
           GK ++RK RFK SDGSTSSDTTSNSFVRQGSA+SYTSRPSDSDVSLEEDREA+R+EAERQ
Sbjct: 29  GKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSAESYTSRPSDSDVSLEEDREALRKEAERQ 88

Query: 75  AQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGR 134
           A AQLEKAKTKPVAFAVRTNV Y+ +  D+VPV G+AI+FE KDFLH+KEK+NNDWWIGR
Sbjct: 89  ALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGR 148

Query: 135 LVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPS 194
           LVKEGCE+GFIPSPVKL+++RL  EQ+ +Q +  SSKSG NSSSSLGD+V  +R+ TPP+
Sbjct: 149 LVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNRLGSSKSGDNSSSSLGDVVTGTRRPTPPA 208

Query: 195 SG-------------------AKSADEQDQWKTAGL-------------FWRFTTEHTPP 222
           SG                   A+  ++    KT+               F++  TEH PP
Sbjct: 209 SGNEMTNLAFELDPLELEEEEAELGEQSGSAKTSVSSVTTPPPHGKRIPFFK-KTEHVPP 267

Query: 223 YDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLN 282
           YDVVPSMRP++LVGPSLKGYEVTDMMQKALFDFLKHRF+GRISITRVTADISLAKRSVLN
Sbjct: 268 YDVVPSMRPIILVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLN 327

Query: 283 NPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIV 342
           NPSKH IIERSNTRSSLAEVQSEIERIFELARTLQLV LDADTINHPAQLSKTSLAPIIV
Sbjct: 328 NPSKHIIIERSNTRSSLAEVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIV 387

Query: 343 YVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLA 402
           Y+KI+SPKVLQRLIKSRGKSQ+KHLNVQ+ A++KLAQCPPE+FD+ILDENQLEDACEHLA
Sbjct: 388 YIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLA 447

Query: 403 DYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQ 444
           +YLEAYWKATHPPSS+ PNPLL+RT+AT++L  SP   SN Q
Sbjct: 448 EYLEAYWKATHPPSSTPPNPLLNRTMATAALAASPAPVSNLQ 489


>gi|54607066 calcium channel, voltage-dependent, beta 4 subunit
           isoform c [Homo sapiens]
          Length = 502

 Score =  636 bits (1641), Expect = 0.0
 Identities = 349/538 (64%), Positives = 404/538 (75%), Gaps = 48/538 (8%)

Query: 20  RKNRFKGSDGSTSSDTTSNSFV-RQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQ 78
           R++R K SDGST    TS SF+ RQGSADSYTSRPSDSDVSLEEDREA+R+E E+QA  Q
Sbjct: 11  RRSRLKRSDGST----TSTSFILRQGSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQ 66

Query: 79  LEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKE 138
           LE+AK+KPVAFAV+TNVSY  A ++DVPVP  AISF+AKDFLH+KEK+NNDWWIGRLVKE
Sbjct: 67  LERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKE 126

Query: 139 GCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSGAK 198
           GCEIGFIPSP++LEN+R+Q EQ  K+G+F+  KS GNSSSSLG++V  + ++TP S+  +
Sbjct: 127 GCEIGFIPSPLRLENIRIQQEQ--KRGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQ 184

Query: 199 SADEQDQWKTAGLFWRFTTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKH 258
                             TEH PPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKH
Sbjct: 185 KQK--------------VTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKH 230

Query: 259 RFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQL 318
           RF+GRISITRVTADISLAKRSVLNNPSK AIIERSNTRSSLAEVQSEIERIFELAR+LQL
Sbjct: 231 RFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQL 290

Query: 319 VVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLA 378
           VVLDADTINHPAQL KTSLAPIIV+VK+SSPKVLQRLIKSRGKSQ+KHLNVQ+VAADKLA
Sbjct: 291 VVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLA 350

Query: 379 QCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPT 438
           QCPPE+FDVILDENQLEDACEHL +YLEAYW+ATH  SS+   PLL R L +++L   PT
Sbjct: 351 QCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTPMTPLLGRNLGSTALSPYPT 410

Query: 439 LASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLS 498
             S  Q          S  +R ++ + E   +E     +   +S   +HN R+  SR   
Sbjct: 411 AISGLQ----------SQRMRHSNHSTENSPIE----RRSLMTSDENYHNERARKSR--- 453

Query: 499 RQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHR 556
                 S +Q SRD  Y   +EDY   + D Y  HR+        GS      +SRHR
Sbjct: 454 --NRLSSSSQHSRDH-YPLVEEDYPDSYQDTYKPHRN-------RGSPGGYSHDSRHR 501


>gi|54607064 calcium channel, voltage-dependent, beta 4 subunit
           isoform b [Homo sapiens]
          Length = 520

 Score =  636 bits (1641), Expect = 0.0
 Identities = 349/538 (64%), Positives = 404/538 (75%), Gaps = 48/538 (8%)

Query: 20  RKNRFKGSDGSTSSDTTSNSFV-RQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQ 78
           R++R K SDGST    TS SF+ RQGSADSYTSRPSDSDVSLEEDREA+R+E E+QA  Q
Sbjct: 29  RRSRLKRSDGST----TSTSFILRQGSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQ 84

Query: 79  LEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKE 138
           LE+AK+KPVAFAV+TNVSY  A ++DVPVP  AISF+AKDFLH+KEK+NNDWWIGRLVKE
Sbjct: 85  LERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKE 144

Query: 139 GCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSGAK 198
           GCEIGFIPSP++LEN+R+Q EQ  K+G+F+  KS GNSSSSLG++V  + ++TP S+  +
Sbjct: 145 GCEIGFIPSPLRLENIRIQQEQ--KRGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQ 202

Query: 199 SADEQDQWKTAGLFWRFTTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKH 258
                             TEH PPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKH
Sbjct: 203 KQK--------------VTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKH 248

Query: 259 RFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQL 318
           RF+GRISITRVTADISLAKRSVLNNPSK AIIERSNTRSSLAEVQSEIERIFELAR+LQL
Sbjct: 249 RFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQL 308

Query: 319 VVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLA 378
           VVLDADTINHPAQL KTSLAPIIV+VK+SSPKVLQRLIKSRGKSQ+KHLNVQ+VAADKLA
Sbjct: 309 VVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLA 368

Query: 379 QCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPT 438
           QCPPE+FDVILDENQLEDACEHL +YLEAYW+ATH  SS+   PLL R L +++L   PT
Sbjct: 369 QCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTPMTPLLGRNLGSTALSPYPT 428

Query: 439 LASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLS 498
             S  Q          S  +R ++ + E   +E     +   +S   +HN R+  SR   
Sbjct: 429 AISGLQ----------SQRMRHSNHSTENSPIE----RRSLMTSDENYHNERARKSR--- 471

Query: 499 RQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHR 556
                 S +Q SRD  Y   +EDY   + D Y  HR+        GS      +SRHR
Sbjct: 472 --NRLSSSSQHSRDH-YPLVEEDYPDSYQDTYKPHRN-------RGSPGGYSHDSRHR 519


>gi|54607068 calcium channel, voltage-dependent, beta 4 subunit
           isoform a [Homo sapiens]
          Length = 486

 Score =  619 bits (1595), Expect = e-177
 Identities = 335/513 (65%), Positives = 387/513 (75%), Gaps = 43/513 (8%)

Query: 44  GSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHED 103
           GSADSYTSRPSDSDVSLEEDREA+R+E E+QA  QLE+AK+KPVAFAV+TNVSY  A ++
Sbjct: 16  GSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDE 75

Query: 104 DVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAK 163
           DVPVP  AISF+AKDFLH+KEK+NNDWWIGRLVKEGCEIGFIPSP++LEN+R+Q EQ  K
Sbjct: 76  DVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQ--K 133

Query: 164 QGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSGAKSADEQDQWKTAGLFWRFTTEHTPPY 223
           +G+F+  KS GNSSSSLG++V  + ++TP S+  +                  TEH PPY
Sbjct: 134 RGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQK--------------VTEHIPPY 179

Query: 224 DVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNN 283
           DVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRF+GRISITRVTADISLAKRSVLNN
Sbjct: 180 DVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNN 239

Query: 284 PSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVY 343
           PSK AIIERSNTRSSLAEVQSEIERIFELAR+LQLVVLDADTINHPAQL KTSLAPIIV+
Sbjct: 240 PSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVH 299

Query: 344 VKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLAD 403
           VK+SSPKVLQRLIKSRGKSQ+KHLNVQ+VAADKLAQCPPE+FDVILDENQLEDACEHL +
Sbjct: 300 VKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGE 359

Query: 404 YLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQ 463
           YLEAYW+ATH  SS+   PLL R L +++L   PT  S  Q          S  +R ++ 
Sbjct: 360 YLEAYWRATHTTSSTPMTPLLGRNLGSTALSPYPTAISGLQ----------SQRMRHSNH 409

Query: 464 AEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYS 523
           + E   +E     +   +S   +HN R+  SR         S +Q SRD  Y   +EDY 
Sbjct: 410 STENSPIE----RRSLMTSDENYHNERARKSR-----NRLSSSSQHSRDH-YPLVEEDYP 459

Query: 524 HDHVDHYASHRDHNHRDETHGSSDHRHRESRHR 556
             + D Y  HR+        GS      +SRHR
Sbjct: 460 DSYQDTYKPHRN-------RGSPGGYSHDSRHR 485


>gi|224831262 calcium channel, voltage-dependent, beta 4 subunit
           isoform d [Homo sapiens]
          Length = 458

 Score =  539 bits (1389), Expect = e-153
 Identities = 314/538 (58%), Positives = 362/538 (67%), Gaps = 110/538 (20%)

Query: 20  RKNRFKGSDGSTSSDTTSNSFV-RQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQ 78
           R++R K SDGST    TS SF+ RQGSADSYTSRPSDSDVSLEEDREA+R+E E+QA  Q
Sbjct: 29  RRSRLKRSDGST----TSTSFILRQGSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQ 84

Query: 79  LEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKE 138
           LE+AK+KPVAFAV+TNVSY  A ++DVPVP  AISF+AKDFLH+KEK+NNDWWIGRLVKE
Sbjct: 85  LERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKE 144

Query: 139 GCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSGAK 198
           GCEIGFIPSP++LEN+R+Q EQ  K+G+F+  KS GNSSSSLG++V  + ++TP S+  +
Sbjct: 145 GCEIGFIPSPLRLENIRIQQEQ--KRGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQ 202

Query: 199 SADEQDQWKTAGLFWRFTTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKH 258
                             TEH PPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKH
Sbjct: 203 KQK--------------VTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKH 248

Query: 259 RFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQL 318
           RF+GRISITRVTADISLAKRSVLNNPSK AIIERSNTRSSLAEVQSEIERIFELAR+LQL
Sbjct: 249 RFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQL 308

Query: 319 VVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLA 378
           VVLDADTINHPAQL KTSLAPIIV+VK+SSPKVLQRLIKSRGKSQ+KHLNVQ+VAADKLA
Sbjct: 309 VVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLA 368

Query: 379 QCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPT 438
           QCPP                           +  H   S+  +P+  R+L TS       
Sbjct: 369 QCPPS-------------------------QRMRHSNHSTENSPIERRSLMTS------- 396

Query: 439 LASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLS 498
                                     +E    E  +KS++R SSS+ H            
Sbjct: 397 --------------------------DENYHNERARKSRNRLSSSSQH------------ 418

Query: 499 RQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHR 556
                      SRD  Y   +EDY   + D Y  HR+        GS      +SRHR
Sbjct: 419 -----------SRDH-YPLVEEDYPDSYQDTYKPHRN-------RGSPGGYSHDSRHR 457


>gi|40316928 calcium channel, voltage-dependent, beta 3 subunit
           [Homo sapiens]
          Length = 484

 Score =  537 bits (1383), Expect = e-152
 Identities = 309/541 (57%), Positives = 365/541 (67%), Gaps = 74/541 (13%)

Query: 44  GSADSYTSRPS-DSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHE 102
           GSADSYTSRPS DSDVSLEEDRE+ RRE E QAQ QLE+AK KPVAFAVRTNVSY    +
Sbjct: 16  GSADSYTSRPSLDSDVSLEEDRESARREVESQAQQQLERAKHKPVAFAVRTNVSYCGVLD 75

Query: 103 DDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRA 162
           ++ PV G  ++FEAKDFLH+KEK++NDWWIGRLVKEG +I FIPSP +LE++RL+ EQ+A
Sbjct: 76  EECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRLVKEGGDIAFIPSPQRLESIRLKQEQKA 135

Query: 163 KQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSGAKSADEQDQWKTAGLFWRFTTEHTPP 222
           ++           + SSL DI   +R+S PPS  AK   +Q              EH PP
Sbjct: 136 RRS---------GNPSSLSDI--GNRRSPPPSL-AKQKQKQ-------------AEHVPP 170

Query: 223 YDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLN 282
           YDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRF+GRISITRVTAD+SLAKRSVLN
Sbjct: 171 YDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADLSLAKRSVLN 230

Query: 283 NPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIV 342
           NP K  IIERS+ RSS+AEVQSEIERIFELA++LQLVVLDADTINHPAQL+KTSLAPIIV
Sbjct: 231 NPGKRTIIERSSARSSIAEVQSEIERIFELAKSLQLVVLDADTINHPAQLAKTSLAPIIV 290

Query: 343 YVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLA 402
           +VK+SSPKVLQRLI+SRGKSQ KHL VQM+A DKL QCPPE FDVILDENQLEDACEHLA
Sbjct: 291 FVKVSSPKVLQRLIRSRGKSQMKHLTVQMMAYDKLVQCPPESFDVILDENQLEDACEHLA 350

Query: 403 DYLEAYWKATHPPSSSLPNP-LLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSA 461
           +YLE YW+ATH P+   P P LL    A   L     L     G +G++ +         
Sbjct: 351 EYLEVYWRATHHPA---PGPGLLGPPSAIPGLQNQQLL-----GERGEEHS--------- 393

Query: 462 SQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKED 521
                     P+++     S  A   + ++ T                 R S ++E  ED
Sbjct: 394 ----------PLERDSLMPSDEASESSRQAWTG-------------SSQRSSRHLE--ED 428

Query: 522 YSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDR 581
           Y+  + D Y  HR H     T G       + + R    D E +H++ N QR+R   KD 
Sbjct: 429 YADAYQDLYQPHRQH-----TSGLPSANGHDPQDRLLAQDSEHNHSDRNWQRNRPWPKDS 483

Query: 582 Y 582
           Y
Sbjct: 484 Y 484


>gi|50962882 G patch domain containing 8 [Homo sapiens]
          Length = 1502

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 49/182 (26%), Positives = 74/182 (40%), Gaps = 30/182 (16%)

Query: 443 SQGSQGDQRTDRSAPIR----SASQAEEEPSVEP--VKKSQHRSSSSAPHHNHRSGTSRG 496
           SQ S GD+ +D ++  R    S SQ  EE   E    + S+ RS S   H +HRS     
Sbjct: 811 SQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSS---- 866

Query: 497 LSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYA------SHRDHNHRDETHGSSDHRH 550
              + ++ S +  S D +    +  YS D    Y+      S R H+  D  + SS HR 
Sbjct: 867 ---RRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRS 923

Query: 551 RESRHRSRDVD----------REQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEW 600
           +  ++ S D D          R + H    + RSR +S+   C +       +   A  W
Sbjct: 924 KRHKYSSSDDDYSLSCSQSRSRSRSHTR-ERSRSRGRSRSSSCSRSRSKRRSRSTTAHSW 982

Query: 601 NR 602
            R
Sbjct: 983 QR 984



 Score = 33.1 bits (74), Expect = 0.76
 Identities = 36/146 (24%), Positives = 55/146 (37%), Gaps = 8/146 (5%)

Query: 441 SNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQ 500
           S S+   G + +   +  RS S + +  S +    S+ RS S   + ++   + R   R 
Sbjct: 850 SRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCY-SRQRSYSDDSYSDYSDRSRRHSKRS 908

Query: 501 ETFD-----SETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRH 555
              D     S    S+   Y    +DYS       +  R  +H  E   S       S  
Sbjct: 909 HDSDDSDYASSKHRSKRHKYSSSDDDYSLS--CSQSRSRSRSHTRERSRSRGRSRSSSCS 966

Query: 556 RSRDVDREQDHNECNKQRSRHKSKDR 581
           RSR   R +     + QRSR  S+DR
Sbjct: 967 RSRSKRRSRSTTAHSWQRSRSYSRDR 992


>gi|119943106 synapse-associated protein 102 isoform a [Homo
           sapiens]
          Length = 817

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 70/320 (21%), Positives = 123/320 (38%), Gaps = 51/320 (15%)

Query: 104 DVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVK---EGCEIGFIPSPVKLENMRLQHEQ 160
           D  +P   +SF   D LHV    +++WW  RLV    E  +IG IPS  ++E    +   
Sbjct: 517 DSCLPSQGLSFSYGDILHVINASDDEWWQARLVTPHGESEQIGVIPSKKRVEK---KERA 573

Query: 161 RAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSGAKSADEQDQWKTAGLFWRFTTEHT 220
           R K  KF++             ++ S+R     S     A      + A L +   T   
Sbjct: 574 RLKTVKFHARTG----------MIESNRDFPGLSDDYYGAKNLKGQEDAILSYEPVTRQE 623

Query: 221 PPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRI-SITRVTADISLAKRS 279
             Y      RPV+++GP      + D +   L     H+F   +   TR   D      +
Sbjct: 624 IHY-----ARPVIILGP------MKDRVNDDLISEFPHKFGSCVPHTTRPRRD------N 666

Query: 280 VLNNPSKHAIIERSNTRSSLAEVQ-------------SEIERIFELARTLQLVVLDADTI 326
            ++    H ++ R      + + +             + I+ +  +A   +  +LD    
Sbjct: 667 EVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQSVRAVAERGKHCILDVSG- 725

Query: 327 NHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFD 386
           N   +L +  L PI +++K   PK ++ L++   +   +  N     A KL Q   E F 
Sbjct: 726 NAIKRLQQAQLYPIAIFIK---PKSIEALMEMNRRQTYEQANKIYDKAMKLEQEFGEYFT 782

Query: 387 VILDENQLEDACEHLADYLE 406
            I+  + LE+    +   +E
Sbjct: 783 AIVQGDSLEEIYNKIKQIIE 802


>gi|148539628 discs, large homolog 1 isoform 1 [Homo sapiens]
          Length = 904

 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 70/322 (21%), Positives = 128/322 (39%), Gaps = 48/322 (14%)

Query: 104 DVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVK---EGCEIGFIPSPVKLENMRLQHEQ 160
           D  +P   ++F+  D LHV    +++WW  R V    E  E+G IPS  ++E    +   
Sbjct: 597 DSGLPSQGLNFKFGDILHVINASDDEWWQARQVTPDGESDEVGVIPSKRRVEK---KERA 653

Query: 161 RAKQGKFYS-SKSGGNSSSSLGDIVPSSRKSTPPSSGAKSADEQDQWKTAGLFWRFTTEH 219
           R K  KF S ++  G     +G      +  T  +S ++S+            +R   E+
Sbjct: 654 RLKTVKFNSKTRDKGEIPDDMGS--KGLKHVTSNASDSESS------------YRGQEEY 699

Query: 220 TPPYDVVPSM-----RPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRI-SITRVTADI 273
              Y+ V        RPV+++GP      + D +   L      +F   +   TR   D 
Sbjct: 700 VLSYEPVNQQEVNYTRPVIILGP------MKDRINDDLISEFPDKFGSCVPHTTRPKRDY 753

Query: 274 SL---------AKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDAD 324
            +         ++  +  +  +H  IE     + L    + ++ + E+A   +  +LD  
Sbjct: 754 EVDGRDYHFVTSREQMEKDIQEHKFIEAGQYNNHL--YGTSVQSVREVAEKGKHCILDVS 811

Query: 325 TINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPEL 384
             N   +L    L PI +++K   PK ++ +++   +   +        A KL Q   E 
Sbjct: 812 G-NAIKRLQIAQLYPISIFIK---PKSMENIMEMNKRLTEEQARKTFERAMKLEQEFTEH 867

Query: 385 FDVILDENQLEDACEHLADYLE 406
           F  I+  + LED    +   +E
Sbjct: 868 FTAIVQGDTLEDIYNQVKQIIE 889


>gi|148539578 discs, large homolog 1 isoform 2 [Homo sapiens]
          Length = 926

 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 77/332 (23%), Positives = 131/332 (39%), Gaps = 46/332 (13%)

Query: 104 DVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVK---EGCEIGFIPSPVKLENMRLQHEQ 160
           D  +P   ++F+  D LHV    +++WW  R V    E  E+G IPS  ++E    +   
Sbjct: 597 DSGLPSQGLNFKFGDILHVINASDDEWWQARQVTPDGESDEVGVIPSKRRVEK---KERA 653

Query: 161 RAKQGKFYS-SKSGGNSSSSLGDIVPSSRKSTPPSSGAKSADEQ-----DQWKTAGL--- 211
           R K  KF S ++  G S +        SRK   P    K   EQ     DQ  T+     
Sbjct: 654 RLKTVKFNSKTRDKGQSFNDKRKKNLFSRKF--PFYKNKDQSEQETSDADQHVTSNASDS 711

Query: 212 --FWRFTTEHTPPYDVVPSM-----RPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRI 264
              +R   E+   Y+ V        RPV+++GP      + D +   L      +F   +
Sbjct: 712 ESSYRGQEEYVLSYEPVNQQEVNYTRPVIILGP------MKDRINDDLISEFPDKFGSCV 765

Query: 265 -SITRVTADISL---------AKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELAR 314
              TR   D  +         ++  +  +  +H  IE     + L    + ++ + E+A 
Sbjct: 766 PHTTRPKRDYEVDGRDYHFVTSREQMEKDIQEHKFIEAGQYNNHL--YGTSVQSVREVAE 823

Query: 315 TLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAA 374
             +  +LD    N   +L    L PI +++K   PK ++ +++   +   +        A
Sbjct: 824 KGKHCILDVSG-NAIKRLQIAQLYPISIFIK---PKSMENIMEMNKRLTEEQARKTFERA 879

Query: 375 DKLAQCPPELFDVILDENQLEDACEHLADYLE 406
            KL Q   E F  I+  + LED    +   +E
Sbjct: 880 MKLEQEFTEHFTAIVQGDTLEDIYNQVKQIIE 911


>gi|4504487 histidine rich calcium binding protein precursor [Homo
           sapiens]
          Length = 699

 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 41/148 (27%), Positives = 60/148 (40%), Gaps = 9/148 (6%)

Query: 462 SQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAY--VEPK 519
           S  + E   E V K            +H+ G   G+S +E F     ++R       E  
Sbjct: 84  SHPDREKEDEDVSKEYGHLLPGHRSQDHKVG-DEGVSGEEVFAEHGGQARGHRGHGSEDT 142

Query: 520 EDYSHDHVDHYASHRDHNHRDETHG---SSDHRHRESRHRSRDVDREQDHNECNKQRSRH 576
           ED S +H  H  SHR H+H+DE      SS+H H   RH  R  D E D  E  ++    
Sbjct: 143 ED-SAEHRHHLPSHRSHSHQDEDEDEVVSSEHHHHILRHGHRGHDGEDDEGE--EEEEEE 199

Query: 577 KSKDRYCEKDGEVISKKRNEAGEWNRDV 604
           + ++    + G    + R    E + DV
Sbjct: 200 EEEEEASTEYGHQAHRHRGHGSEEDEDV 227



 Score = 38.9 bits (89), Expect = 0.014
 Identities = 33/141 (23%), Positives = 53/141 (37%), Gaps = 16/141 (11%)

Query: 449 DQRTDRSAPIRSASQAEEEPSVEPVKKS-QHRSSSS------APHHNHRSGTSRGLSRQE 501
           D   D         + EEE S E   ++ +HR   S      +  H+H   + R    +E
Sbjct: 186 DGEDDEGEEEEEEEEEEEEASTEYGHQAHRHRGHGSEEDEDVSDGHHHHGPSHRHQGHEE 245

Query: 502 TFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSR--- 558
             D +  +  D    +  +D S ++      H+ H   ++   S  H HR+  HR R   
Sbjct: 246 DDDDDDDDDDD----DDDDDVSIEYRHQAHRHQGHGIEEDEDVSDGHHHRDPSHRHRSHE 301

Query: 559 --DVDREQDHNECNKQRSRHK 577
             D D +    E   Q  RH+
Sbjct: 302 EDDNDDDDVSTEYGHQAHRHQ 322



 Score = 33.5 bits (75), Expect = 0.58
 Identities = 23/100 (23%), Positives = 37/100 (37%), Gaps = 6/100 (6%)

Query: 487 HNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSS 546
           H+HR  + R  S +E  + +   S +  +       +H H DH     +    +  H   
Sbjct: 288 HHHRDPSHRHRSHEEDDNDDDDVSTEYGH------QAHRHQDHRKEEVEAVSGEHHHHVP 341

Query: 547 DHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKD 586
           DHRH+  R    D D   +      Q   H   D   E++
Sbjct: 342 DHRHQGHRDEEEDEDVSTERWHQGPQHVHHGLVDEEEEEE 381



 Score = 30.8 bits (68), Expect = 3.8
 Identities = 25/126 (19%), Positives = 48/126 (38%), Gaps = 8/126 (6%)

Query: 456 APIRSASQAEEEPSVEPVKKSQHRSSSSAPHH--NHRSGTSRGLSRQETFDSETQESRDS 513
           AP    S  +EE         Q  S     HH   H     R   R++  + E ++  D 
Sbjct: 438 APSHRQSHQDEETG-----HGQRGSIKEMSHHPPGHTVVKDRSHLRKDDSEEEKEKEEDP 492

Query: 514 AYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQR 573
              E ++D S +  +    H   +  DE      H    ++    + D+E++  E +++R
Sbjct: 493 GSHE-EDDESSEQGEKGTHHGSRDQEDEEDEEEGHGLSLNQEEEEEEDKEEEEEEEDEER 551

Query: 574 SRHKSK 579
              +++
Sbjct: 552 REERAE 557


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 47/177 (26%), Positives = 68/177 (38%), Gaps = 17/177 (9%)

Query: 415 PSSSLPNPLLSRTLATSSLPLSPTLASN---SQGSQGDQRTDRSAPI------RSASQAE 465
           P    P PLL+     S  PL+ T  S    +  S+     DRS P       +S+S   
Sbjct: 361 PEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSES 420

Query: 466 EEPSVEPVKKSQHRSSS-SAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSH 524
             PS +P K S+H SSS  +P      G+ R +S   T       S++ ++   K D SH
Sbjct: 421 SPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPT-------SKNRSHGRAKRDKSH 473

Query: 525 DHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDR 581
            H       R  +      G S  R    R  SR    +   +   ++  R +S  R
Sbjct: 474 SHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQR 530



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 30/136 (22%), Positives = 56/136 (41%), Gaps = 11/136 (8%)

Query: 415 PSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVK 474
           P+   P P      ++SS   +P      +     +R++ S+P R   ++         K
Sbjct: 163 PAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSS--------K 214

Query: 475 KSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHR 534
           K +HRS S +    HRS T +  S++++ D + + SR S    PK   +H      ++  
Sbjct: 215 KKKHRSESESKKRKHRSPTPK--SKRKSKDKKRKRSR-STTPAPKSRRAHRSTSADSASS 271

Query: 535 DHNHRDETHGSSDHRH 550
               R  +  ++   H
Sbjct: 272 SDTSRSRSRSAAAKTH 287



 Score = 34.7 bits (78), Expect = 0.26
 Identities = 42/187 (22%), Positives = 69/187 (36%), Gaps = 21/187 (11%)

Query: 415  PSSSLPNPLLSRTLA-TSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPV 473
            P +  P  L  R+ + +SS    P+   +S      +   +S   R  S++  EP  +  
Sbjct: 1624 PKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSR 1683

Query: 474  KKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSET--------QESRDSAYVEPKEDYSHD 525
               + RSS S+P    ++  SR  SR  +   ET        + S   +  EP E     
Sbjct: 1684 TPPRRRSSRSSPELTRKARLSR-RSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSS 1742

Query: 526  HVDHYA--------SHRDHNHRDETHGSSDHRHRESRHRSRDV---DREQDHNECNKQRS 574
                 A        S R  +   +  G    R R  R ++R     DR       +++R 
Sbjct: 1743 RRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQ 1802

Query: 575  RHKSKDR 581
            R +S+ R
Sbjct: 1803 RSRSRSR 1809



 Score = 32.7 bits (73), Expect = 1.00
 Identities = 28/93 (30%), Positives = 40/93 (43%), Gaps = 18/93 (19%)

Query: 416 SSSLPNPLLSRTLATSSLPLSPTLASNS---------------QGSQGDQRTDRSAPIRS 460
           S SL +P   R+ A S L L  +L+ +S                GS   +   R+ P RS
Sbjct: 759 SRSLSSP---RSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRS 815

Query: 461 ASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGT 493
            S +   P  +    S+   SSS+PH   +SGT
Sbjct: 816 RSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGT 848



 Score = 32.0 bits (71), Expect = 1.7
 Identities = 38/154 (24%), Positives = 59/154 (38%), Gaps = 14/154 (9%)

Query: 436  SPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGT-- 493
            SP    +S+ S   +R     P  S  ++    S  P K+S+ R +S A H   RS T  
Sbjct: 1824 SPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSR-ASPATHRRSRSRTPL 1882

Query: 494  -SRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNH-----RDETHGSSD 547
             SR  SR  T     + SR    V  +   S       +  R  +      R  +   + 
Sbjct: 1883 ISRRRSRSRTSPVSRRRSRSRTSVTRRR--SRSRASPVSRRRSRSRTPPVTRRRSRSRTP 1940

Query: 548  HRHRESRHRSRDVDREQDHNE---CNKQRSRHKS 578
               R SR R+  V R +  +      ++RSR ++
Sbjct: 1941 TTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRT 1974



 Score = 30.0 bits (66), Expect = 6.5
 Identities = 28/120 (23%), Positives = 47/120 (39%), Gaps = 16/120 (13%)

Query: 411  ATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIR---------SA 461
            A  P      +   S + ++SS   S + +S+S GS        S P++         S 
Sbjct: 2523 ALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSP 2582

Query: 462  SQAEEE-------PSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSA 514
            + A +E       P   P K+ +  SSSS+   +  S +S   S   +  S +  S  S+
Sbjct: 2583 TPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2642


>gi|218156338 chapsyn-110 isoform 1 [Homo sapiens]
          Length = 975

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 70/322 (21%), Positives = 125/322 (38%), Gaps = 33/322 (10%)

Query: 91  VRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVK---EGCEIGFIPS 147
           VR    Y  + +  +P  G+  SF+  D LHV    +++WW  R V    +  E+G IPS
Sbjct: 646 VRAMFDYDKSKDSGLPSQGL--SFKYGDILHVINASDDEWWQARRVMLEGDSEEMGVIPS 703

Query: 148 PVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSS---RKSTPPSSGAKSADEQD 204
             ++E    +   R K  KF +     +S  S  D    S    +  P     + ++++ 
Sbjct: 704 KRRVER---KERARLKTVKFNAKPGVIDSKGSFNDKRKKSFIFSRKFPFYKNKEQSEQET 760

Query: 205 QWKTAGLFWRFTTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRI 264
                G      +        +   RPV+++GP      + D +   L      +F   +
Sbjct: 761 SDPERGQEDLILSYEPVTRQEINYTRPVIILGP------MKDRINDDLISEFPDKFGSCV 814

Query: 265 -SITRVTADIS---------LAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELAR 314
              TR   D           +++  +  +  +H  IE      +L    + ++ +  +A 
Sbjct: 815 PHTTRPKRDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNL--YGTSVQSVRFVAE 872

Query: 315 TLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAA 374
             +  +LD    N   +L    L PI +++K  S + L  + K   + QAK    + +  
Sbjct: 873 RGKHCILDVSG-NAIKRLQVAQLYPIAIFIKPRSLEPLMEMNKRLTEEQAKKTYDRAI-- 929

Query: 375 DKLAQCPPELFDVILDENQLED 396
            KL Q   E F  I+  + LED
Sbjct: 930 -KLEQEFGEYFTAIVQGDTLED 950


>gi|91199538 chapsyn-110 isoform 2 [Homo sapiens]
          Length = 870

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 70/322 (21%), Positives = 125/322 (38%), Gaps = 33/322 (10%)

Query: 91  VRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVK---EGCEIGFIPS 147
           VR    Y  + +  +P  G+  SF+  D LHV    +++WW  R V    +  E+G IPS
Sbjct: 541 VRAMFDYDKSKDSGLPSQGL--SFKYGDILHVINASDDEWWQARRVMLEGDSEEMGVIPS 598

Query: 148 PVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSS---RKSTPPSSGAKSADEQD 204
             ++E    +   R K  KF +     +S  S  D    S    +  P     + ++++ 
Sbjct: 599 KRRVER---KERARLKTVKFNAKPGVIDSKGSFNDKRKKSFIFSRKFPFYKNKEQSEQET 655

Query: 205 QWKTAGLFWRFTTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRI 264
                G      +        +   RPV+++GP      + D +   L      +F   +
Sbjct: 656 SDPERGQEDLILSYEPVTRQEINYTRPVIILGP------MKDRINDDLISEFPDKFGSCV 709

Query: 265 -SITRVTADIS---------LAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELAR 314
              TR   D           +++  +  +  +H  IE      +L    + ++ +  +A 
Sbjct: 710 PHTTRPKRDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNL--YGTSVQSVRFVAE 767

Query: 315 TLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAA 374
             +  +LD    N   +L    L PI +++K  S + L  + K   + QAK    + +  
Sbjct: 768 RGKHCILDVSG-NAIKRLQVAQLYPIAIFIKPRSLEPLMEMNKRLTEEQAKKTYDRAI-- 824

Query: 375 DKLAQCPPELFDVILDENQLED 396
            KL Q   E F  I+  + LED
Sbjct: 825 -KLEQEFGEYFTAIVQGDTLED 845


>gi|9945320 cyclin L1 [Homo sapiens]
          Length = 526

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 36/142 (25%), Positives = 62/142 (43%), Gaps = 16/142 (11%)

Query: 440 ASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSR 499
           AS S  +   + + RS   RSAS++          +S+ RS +   H+N+R       SR
Sbjct: 371 ASKSPYNGVRKDSKRSRNSRSASRSRSRT------RSRSRSHTPRRHYNNRR------SR 418

Query: 500 QETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRD 559
             T+ S ++    S    P+  ++H      A H     RD+   S+ H H+  + RSR 
Sbjct: 419 SGTYSSRSRSRSRSHSESPRRHHNHGSPHLKAKHT----RDDLKSSNRHGHKRKKSRSRS 474

Query: 560 VDREQDHNECNKQRSRHKSKDR 581
             + +DH++  K+    +   R
Sbjct: 475 QSKSRDHSDAAKKHRHERGHHR 496


>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
           sapiens]
          Length = 434

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 38/151 (25%), Positives = 64/151 (42%), Gaps = 12/151 (7%)

Query: 464 AEEEPSVEPVKKSQHRSSSSAPHHN-HRSGTSRGLSRQETFDSETQESRDSAYVEPKEDY 522
           A E+ S +  KK +    S +P  + H    SR  SR+    S+ +  +  +    KE  
Sbjct: 12  APEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGR 71

Query: 523 SHDHVDHYA-SHRDHNHRDETHGSSDHRHR-------ESRH--RSRDVDREQDHNECNKQ 572
            H+  D  +  H+   H D+ H S   R R       E RH  + R   R + H+    +
Sbjct: 72  RHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSR 131

Query: 573 RSRHKSKDRYCEKDGEVISKKRNEAGEWNRD 603
             RH+S+ R   K     S++R ++   +R+
Sbjct: 132 ERRHRSRSRE-RKKSRSRSRERKKSRSRSRE 161



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 39/177 (22%), Positives = 72/177 (40%), Gaps = 28/177 (15%)

Query: 453 DRSAPIRSASQAEEEPSVEPVKKSQH-------------RSSSSAPHHNHRSGTSRGLSR 499
           ++++P R   + + E SV P     H             +S +    H  RS +  G  R
Sbjct: 14  EKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEG-RR 72

Query: 500 QETFDSETQESRDSAY--VEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRH-----RE 552
            E+ D  +++ +   +   E   D   + ++   +  D + R E   S    H     RE
Sbjct: 73  HESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRE 132

Query: 553 SRHRSRDVDREQDHNEC-------NKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNR 602
            RHRSR  +R++  +         ++ R R KS+ R  E+   + S+ R+ +   +R
Sbjct: 133 RRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHR 189



 Score = 36.2 bits (82), Expect = 0.090
 Identities = 42/170 (24%), Positives = 64/170 (37%), Gaps = 18/170 (10%)

Query: 441 SNSQGSQGDQRTDRSA-PIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSR 499
           S S+  +  +++D      RS S+++E    E   KS  +  S   H++    + +G  R
Sbjct: 43  SRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEE-HNDKEHSSDKG--R 99

Query: 500 QETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRE------- 552
           +    SE  E R     E K      H    +  R H  R      S  R RE       
Sbjct: 100 ERLNSSENGEDRHKRK-ERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSR 158

Query: 553 ------SRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNE 596
                 SR RSR+  R       ++ R RH+++ R   +      KKR E
Sbjct: 159 SRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIE 208


>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
           containing B [Homo sapiens]
          Length = 546

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 42/167 (25%), Positives = 61/167 (36%), Gaps = 20/167 (11%)

Query: 445 GSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFD 504
           G +G +  DR    R +       S+ P  +   R S S  HH    G+S    R+   +
Sbjct: 244 GKEGAEEIDRHVERRRSRSPRR--SLSP--RRSPRRSRSRSHHREGHGSS-SFDRELERE 298

Query: 505 SETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQ 564
            E Q     A    KE      +D     R    R+     S  R R+   R RD +RE+
Sbjct: 299 KERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREK 358

Query: 565 DH---------------NECNKQRSRHKSKDRYCEKDGEVISKKRNE 596
           ++               NE  K+R R + + +     GEV  KK  E
Sbjct: 359 ENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKE 405



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 49/184 (26%), Positives = 69/184 (37%), Gaps = 38/184 (20%)

Query: 450 QRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGT---------------- 493
           QR +R A  R   + E   S    +  + R S S   H  RS +                
Sbjct: 302 QRLEREAKER---EKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREK 358

Query: 494 --SRGLSRQETFD----SETQESRDSAYVEPKEDYSHDHVD---HYASHRDHNHRDETHG 544
              RG  R   +D    +E ++ R+ +    KE  S   V+   H     D  HRD+   
Sbjct: 359 ENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRD 418

Query: 545 S------SDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAG 598
           S      S  R RE +HRSR   R    N   + RSR K K    + + +  S KR+ +G
Sbjct: 419 SKKEKKHSRSRSRERKHRSRSRSR----NAGKRSRSRSKEKSSKHKNESKEKSNKRSRSG 474

Query: 599 EWNR 602
              R
Sbjct: 475 SQGR 478



 Score = 35.0 bits (79), Expect = 0.20
 Identities = 36/174 (20%), Positives = 65/174 (37%), Gaps = 18/174 (10%)

Query: 442 NSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQE 501
           N +  + ++  +RS   RS  + EE+   E     +HR          +   SR   R+ 
Sbjct: 376 NEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKH 435

Query: 502 TFDSETQESRDSAYVEPKEDYS-HDHVDHYASHR-----DHNHRDETHGSSDHRHRES-- 553
              S ++ +   +    KE  S H +     S++          D    S    H  S  
Sbjct: 436 RSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKE 495

Query: 554 ----RHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRD 603
               R RS++   ++DH++   Q  +H   DR   +  + I ++  E    N+D
Sbjct: 496 KSRKRSRSKERSHKRDHSDSKDQSDKH---DR---RRSQSIEQESQEKQHKNKD 543



 Score = 34.7 bits (78), Expect = 0.26
 Identities = 34/157 (21%), Positives = 61/157 (38%), Gaps = 8/157 (5%)

Query: 441 SNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQ 500
           S S+  +GD+R DR       ++       +  K+  +           RS   R  SR 
Sbjct: 340 SRSRDRKGDRR-DRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQR--SRG 396

Query: 501 ETFDSETQESRDSA-YVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRD 559
           E  + + +E +D   + + K D   +     +  R+  HR      S  R+   R RSR 
Sbjct: 397 EVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSR----SRSRNAGKRSRSRS 452

Query: 560 VDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNE 596
            ++   H   +K++S  +S+     +   V   K+ E
Sbjct: 453 KEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKRE 489



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 38/171 (22%), Positives = 62/171 (36%), Gaps = 11/171 (6%)

Query: 426 RTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAP 485
           R+L+    P      S+ +   G    DR        Q  E  + E  ++ + R S S  
Sbjct: 265 RSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKE--REKERRRSRSID 322

Query: 486 HHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGS 545
                 G  R  SR          SRD        D   +  +     RD ++ D+  G+
Sbjct: 323 R-----GLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDY-DKERGN 376

Query: 546 SDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNE 596
              + RE   RSR+  +EQ      +++   + KD    +D +  SKK  +
Sbjct: 377 EREKERE---RSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKK 424


>gi|14149807 coiled-coil domain containing 55 isoform 1 [Homo
           sapiens]
          Length = 558

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 34/134 (25%), Positives = 61/134 (45%), Gaps = 16/134 (11%)

Query: 475 KSQHRSSS-------SAPHHNHRSGTSRGLSRQETFDSETQESRDSA-------YVEPKE 520
           +SQ+ S S       S  HH   S TSRG  ++E    + ++SRD         Y + ++
Sbjct: 284 RSQNHSRSPSEERGHSTRHHTKGSRTSRGHEKRED-QHQQKQSRDQENHYTDRDYRKERD 342

Query: 521 DYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKD 580
            + H    H  SH   + +++   + D R R  R   R+ DRE+ +++  ++R R ++  
Sbjct: 343 SHRHREASHRDSHWKRHEQEDKPRARDQRERSDRVWKREKDREK-YSQREQERDRQQNDQ 401

Query: 581 RYCEKDGEVISKKR 594
               + GE   K +
Sbjct: 402 NRPSEKGEKEEKSK 415



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 31/116 (26%), Positives = 52/116 (44%), Gaps = 10/116 (8%)

Query: 478 HRSSSSAPHHNHRSGTSRGLS-RQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDH 536
           HRS +    H+      RG S R  T  S T    +    + ++  S D  +HY   RD+
Sbjct: 283 HRSQN----HSRSPSEERGHSTRHHTKGSRTSRGHEKREDQHQQKQSRDQENHYTD-RDY 337

Query: 537 NHRDETHGSSDHRHRES---RHRSRDVDREQDHNE-CNKQRSRHKSKDRYCEKDGE 588
               ++H   +  HR+S   RH   D  R +D  E  ++   R K +++Y +++ E
Sbjct: 338 RKERDSHRHREASHRDSHWKRHEQEDKPRARDQRERSDRVWKREKDREKYSQREQE 393



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 71/348 (20%), Positives = 131/348 (37%), Gaps = 37/348 (10%)

Query: 275 LAKRSVLNNPS----KHAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPA 330
           L K SV  N S    + ++ E     ++  +   + +   + A      V + D+I    
Sbjct: 23  LQKPSVFGNDSDDDDETSVSESLQREAAKKQAMKQTKLEIQKALAEDATVYEYDSIYDEM 82

Query: 331 QLSKTSLAPIIVYVKISSPKVLQRLIKS---RGKSQAKHLNVQMVAADKLAQCP------ 381
           Q  K    P ++  K   PK +  L+K+   R K Q K +  ++    ++ +        
Sbjct: 83  QKKKEENNPKLLLGKDRKPKYIHNLLKAVEIRKKEQEKRMEKKIQREREMEKGEFDDKEA 142

Query: 382 --PELFDVILDENQLEDACEHLADYLEAYWKATHPPS-SSLPNPLLSRTLATSSLPLSPT 438
                +   L E   E+  E  A  LEA    T     S     LL++ +    +P    
Sbjct: 143 FVTSAYKKKLQERAEEEEREKRAAALEACLDVTKQKDLSGFYRHLLNQAVGEEEVPKCSF 202

Query: 439 LASNSQGSQGDQRTDRSAPIRSASQAEEEPSV---------EPVKKSQHRSSSSAPHHNH 489
             + S G + ++    S  + S ++  +E  +          P   S   + SSA     
Sbjct: 203 REARS-GIKEEKSRGFSNEVSSKNRIPQEKCILQTDVKVEENPDADSDFDAKSSADDEIE 261

Query: 490 RSGTS-RGLSRQETFDSETQESRDSAYVE-PKEDYSHD---HVDHYASHRDHNHRDETHG 544
            +  + R     ET +++ +  R   +   P E+  H    H     + R H  R++ H 
Sbjct: 262 ETRVNCRREKVIETPENDFKHHRSQNHSRSPSEERGHSTRHHTKGSRTSRGHEKREDQHQ 321

Query: 545 SSDHRHRESRHRSRDVDREQD---HNECNKQRS---RHKSKDRYCEKD 586
               R +E+ +  RD  +E+D   H E + + S   RH+ +D+   +D
Sbjct: 322 QKQSRDQENHYTDRDYRKERDSHRHREASHRDSHWKRHEQEDKPRARD 369



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 33/147 (22%), Positives = 53/147 (36%), Gaps = 10/147 (6%)

Query: 449 DQRTDRSAPIRSASQAEEEPSVEPVKKSQH-RSSSSAPHHNHRSGTSRGLSRQETFDSET 507
           D    R A  R +     E   +P  + Q  RS         R   S+    ++   ++ 
Sbjct: 342 DSHRHREASHRDSHWKRHEQEDKPRARDQRERSDRVWKREKDREKYSQREQERDRQQNDQ 401

Query: 508 QESRDSAYVEPKEDYSHDHV-------DHYASHRDHNHRDETHGSSDHRH--RESRHRSR 558
               +    E K     +H+       ++   +RD   R+    SS+     +ES   SR
Sbjct: 402 NRPSEKGEKEEKSKAKEEHMKVRKERYENNDKYRDREKREVGVQSSERNQDRKESSPNSR 461

Query: 559 DVDREQDHNECNKQRSRHKSKDRYCEK 585
             D+  D    NK R+  K K+R  EK
Sbjct: 462 AKDKFLDQERSNKMRNMAKDKERNQEK 488


>gi|23111062 splicing factor, arginine/serine-rich 8 [Homo sapiens]
          Length = 951

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 62/257 (24%), Positives = 103/257 (40%), Gaps = 30/257 (11%)

Query: 336 SLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLE 395
           ++AP  V V+   P++ Q  ++++   Q     +   A +KLAQ   E  +  L   +  
Sbjct: 626 AVAPPCVVVEEKKPQLTQEELEAKQAKQKLEDRLAAAAREKLAQASKESKEKQLQAERKR 685

Query: 396 DACEHLADYLEAYWKA----------THPPSSSLPNPLLSRTLATSSLPLSPTLASNSQG 445
            A   L        +A          +   SS+ P PLL     T   PL PTL    + 
Sbjct: 686 KAALFLQTLKNPLPEAEAGKIEESPFSVEESSTTPCPLL-----TGGRPL-PTL----EV 735

Query: 446 SQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDS 505
              D+ + +S   +   + EE+   +   K + R+ S +P + H S  SR  S      S
Sbjct: 736 KPPDRPSSKS---KDPPREEEKEKKKKKHKKRSRTRSRSPKY-HSSSKSRSRSH-----S 786

Query: 506 ETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQD 565
           + + S  SAY   +   S        +H     R+E    + +R   S   SR   R + 
Sbjct: 787 KAKHSLPSAYRTVRRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSRS 846

Query: 566 -HNECNKQRSRHKSKDR 581
            H +  K+RSR ++K +
Sbjct: 847 PHEKKKKRRSRSRTKSK 863


>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
          Length = 715

 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 45/183 (24%), Positives = 76/183 (41%), Gaps = 17/183 (9%)

Query: 436 SPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNH---RSG 492
           SPT  S+   S     T       S S++         K++  R  S +   NH   RS 
Sbjct: 258 SPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSR 317

Query: 493 TSRGL----SRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNH-----RDETH 543
           T +G+     R     S ++    +    P+   SH+   + +  R H+H     ++  H
Sbjct: 318 TRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDH 377

Query: 544 -GSSDHRHRESRHRSRDVDREQDHNEC---NKQRSRHKSKDRYCEKDGEVISKKRNEAGE 599
            GSS  R    R +S   ++++DH+     NK R R +S+  Y  +D    S+  N+A +
Sbjct: 378 RGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARD-RSRSRSPNKARD 436

Query: 600 WNR 602
            +R
Sbjct: 437 CSR 439



 Score = 37.7 bits (86), Expect = 0.031
 Identities = 35/162 (21%), Positives = 68/162 (41%), Gaps = 16/162 (9%)

Query: 436 SPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPH--HNHRSGT 493
           SP  A +   S+   +    +  RS ++A +        K++ RS S +P+   +H    
Sbjct: 406 SPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSR 465

Query: 494 SRGLSRQETFDSETQESRDSAYV-EPKEDYSHDHV----------DHYASHRDHNHRDET 542
           S   +R  +      + RD + +  P ++  H                +S ++ +HR   
Sbjct: 466 SPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSR 525

Query: 543 HGSSDHRHRESRHRSRDVDREQDHN---ECNKQRSRHKSKDR 581
             S + + R+SR  +++ DR Q  +   E   ++SR  SK+R
Sbjct: 526 SPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKER 567



 Score = 36.2 bits (82), Expect = 0.090
 Identities = 37/157 (23%), Positives = 65/157 (41%), Gaps = 12/157 (7%)

Query: 436 SPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAP-----HHNHR 490
           SP  A +   S+   +    +  RS ++A +        K +  S   +P     H   R
Sbjct: 442 SPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSR 501

Query: 491 SGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHR- 549
           S +     RQ    S+ ++ R S    P ++            RD   R ++   S+ R 
Sbjct: 502 SPSKERQCRQSRSSSKERDHRRSR--SPSKERQRRQSRSPNKERD---RSQSRSPSEERE 556

Query: 550 HRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKD 586
           HR+SR  S++ DR +  +  +K+R R +S+    E+D
Sbjct: 557 HRQSRSPSKERDRRRWRSP-SKERERRQSRSSSEERD 592



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 45/180 (25%), Positives = 61/180 (33%), Gaps = 15/180 (8%)

Query: 409 WKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEP 468
           +KA     S  PN     + + S         S S   + D     S       +    P
Sbjct: 444 YKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSP 503

Query: 469 SVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVD 528
           S E   +    SS    H   RS +     RQ    S  +E   S    P E+      +
Sbjct: 504 SKERQCRQSRSSSKERDHRRSRSPSKERQRRQSR--SPNKERDRSQSRSPSEER-----E 556

Query: 529 HYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNEC---NKQ----RSRHKSKDR 581
           H  S      RD     S  + RE R +SR    E+DH+     NKQ    R R  SK++
Sbjct: 557 HRQSRSPSKERDRRRWRSPSKERE-RRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEK 615



 Score = 34.7 bits (78), Expect = 0.26
 Identities = 42/174 (24%), Positives = 66/174 (37%), Gaps = 32/174 (18%)

Query: 409 WKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQG-SQGDQRTDRSAPIRSASQAEEE 467
           WK  H  + S      +R    S +       S+S+G SQ   RT R     + S+    
Sbjct: 307 WKRNHSRARSR-----TRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSR---N 358

Query: 468 PSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHV 527
           PS E   +S   S SS+   +HR  +S             +ES  S    P +   H   
Sbjct: 359 PSKE---RSHSHSRSSSKERDHRGSSS-----------PRKESGRSQSGSPNKQRDHSRS 404

Query: 528 DHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDR 581
                 RD +     + + D     S +++RD         C++ RS +K++DR
Sbjct: 405 RSPNKARDRSRSRSPYKARDRSRSRSPNKARD---------CSRSRSPYKARDR 449


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.126    0.359 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,390,074
Number of Sequences: 37866
Number of extensions: 1077758
Number of successful extensions: 6933
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 115
Number of HSP's successfully gapped in prelim test: 256
Number of HSP's that attempted gapping in prelim test: 5090
Number of HSP's gapped (non-prelim): 1397
length of query: 608
length of database: 18,247,518
effective HSP length: 108
effective length of query: 500
effective length of database: 14,157,990
effective search space: 7078995000
effective search space used: 7078995000
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.