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Search of human proteins with 147904340
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|147904340 WD repeat domain 82 [Homo sapiens]
(313 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|147904340 WD repeat domain 82 [Homo sapiens] 642 0.0
gi|16554629 WD repeat domain 5 [Homo sapiens] 114 1e-25
gi|16554627 WD repeat domain 5 [Homo sapiens] 114 1e-25
gi|23199987 WD repeat domain 5B [Homo sapiens] 114 1e-25
gi|61743926 F-box and WD repeat domain containing 7 isoform 3 [H... 83 4e-16
gi|16117781 F-box and WD repeat domain containing 7 isoform 1 [H... 83 4e-16
gi|16117779 F-box and WD repeat domain containing 7 isoform 2 [H... 83 4e-16
gi|20357529 guanine nucleotide-binding protein, beta-2 subunit [... 77 2e-14
gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens] 77 2e-14
gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens] 77 2e-14
gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens] 77 2e-14
gi|70909324 sperm associated antigen 16 isoform 1 [Homo sapiens] 77 2e-14
gi|11055998 guanine nucleotide-binding protein, beta-4 subunit [... 77 3e-14
gi|32189425 WD repeat domain 69 [Homo sapiens] 76 3e-14
gi|124256480 APG16 autophagy 16-like isoform 1 [Homo sapiens] 75 6e-14
gi|124256478 APG16 autophagy 16-like isoform 2 [Homo sapiens] 75 6e-14
gi|113865883 WD repeat domain 38 [Homo sapiens] 70 2e-12
gi|11321585 guanine nucleotide-binding protein, beta-1 subunit [... 70 2e-12
gi|199559532 Abelson helper integration site 1 isoform b [Homo s... 69 4e-12
gi|199559490 Abelson helper integration site 1 isoform a [Homo s... 69 4e-12
gi|199559438 Abelson helper integration site 1 isoform a [Homo s... 69 4e-12
gi|31542701 Abelson helper integration site 1 isoform a [Homo sa... 69 4e-12
gi|4557741 platelet-activating factor acetylhydrolase, isoform I... 69 7e-12
gi|5729852 guanine nucleotide-binding protein, beta-5 subunit is... 67 2e-11
gi|20336270 guanine nucleotide-binding protein, beta-5 subunit i... 67 2e-11
gi|21071067 TBP-associated factor 5 [Homo sapiens] 67 2e-11
gi|153791298 mitogen-activated protein kinase organizer 1 [Homo ... 67 2e-11
gi|14150114 mitogen-activated protein kinase organizer 1 [Homo s... 67 2e-11
gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo s... 67 3e-11
gi|13376840 WD repeat domain 61 [Homo sapiens] 66 5e-11
>gi|147904340 WD repeat domain 82 [Homo sapiens]
Length = 313
Score = 642 bits (1657), Expect = 0.0
Identities = 313/313 (100%), Positives = 313/313 (100%)
Query: 1 MKLTDSVLRSFRVAKVFRENSDKINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLY 60
MKLTDSVLRSFRVAKVFRENSDKINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLY
Sbjct: 1 MKLTDSVLRSFRVAKVFRENSDKINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLY 60
Query: 61 SKKYGVDLIRYTHAANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDD 120
SKKYGVDLIRYTHAANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDD
Sbjct: 61 SKKYGVDLIRYTHAANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDD 120
Query: 121 TFISGSLDKTIRLWDLRSPNCQGLMHLQGKPVCSFDPEGLIFAAGVNSEMVKLYDLRSFD 180
TFISGSLDKTIRLWDLRSPNCQGLMHLQGKPVCSFDPEGLIFAAGVNSEMVKLYDLRSFD
Sbjct: 121 TFISGSLDKTIRLWDLRSPNCQGLMHLQGKPVCSFDPEGLIFAAGVNSEMVKLYDLRSFD 180
Query: 181 KGPFATFKMQYDRTCEWTGLKFSNDGKLILISTNGSFIRLIDAFKGVVMHTFGGYANSKA 240
KGPFATFKMQYDRTCEWTGLKFSNDGKLILISTNGSFIRLIDAFKGVVMHTFGGYANSKA
Sbjct: 181 KGPFATFKMQYDRTCEWTGLKFSNDGKLILISTNGSFIRLIDAFKGVVMHTFGGYANSKA 240
Query: 241 VTLEASFTPDSQFIMIGSEDGKIHVWNGESGIKVAVLDGKHTGPITCLQFNPKFMTFASA 300
VTLEASFTPDSQFIMIGSEDGKIHVWNGESGIKVAVLDGKHTGPITCLQFNPKFMTFASA
Sbjct: 241 VTLEASFTPDSQFIMIGSEDGKIHVWNGESGIKVAVLDGKHTGPITCLQFNPKFMTFASA 300
Query: 301 CSNMAFWLPTIDD 313
CSNMAFWLPTIDD
Sbjct: 301 CSNMAFWLPTIDD 313
>gi|16554629 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 114 bits (285), Expect = 1e-25
Identities = 76/287 (26%), Positives = 139/287 (48%), Gaps = 25/287 (8%)
Query: 24 INCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLYSKKYGVDLIRYTHAANTVVYSSN 83
++ FSPNGE + SSS D I ++ +GK ++T+ K G+ + ++ +N +V +S+
Sbjct: 48 VSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASD 107
Query: 84 KIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKTIRLWDLRSPNCQG 143
D T++ + K ++ GHS V + +P + +SGS D+++R+WD+++ C
Sbjct: 108 --DKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLK 165
Query: 144 LMHLQGKPVCS--FDPEGLIFAAGVNSEMVKLYDLRSF--------DKGPFATFKMQYDR 193
+ PV + F+ +G + + + +++D S D P +F
Sbjct: 166 TLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSF------ 219
Query: 194 TCEWTGLKFSNDGKLILISTNGSFIRLIDAFKGVVMHTFGGYANSKAVTLEASFTPDSQF 253
+KFS +GK IL +T + ++L D KG + T+ G+ N K ++
Sbjct: 220 ------VKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKW 273
Query: 254 IMIGSEDGKIHVWNGESGIKVAVLDGKHTGPITCLQFNPKFMTFASA 300
I+ GSED +++WN ++ V L G HT + +P ASA
Sbjct: 274 IVSGSEDNLVYIWNLQTKEIVQKLQG-HTDVVISTACHPTENIIASA 319
Score = 50.4 bits (119), Expect = 2e-06
Identities = 31/133 (23%), Positives = 61/133 (45%), Gaps = 3/133 (2%)
Query: 10 SFRVAKVFRENSDKINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLYSKKYGVDLI 69
S + K + +S+ + C +F+P ++S S D+S+ ++D + GK +TL + V +
Sbjct: 118 SGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAV 177
Query: 70 RYTHAANTVVYSSNKIDDTIRYLSLHDNKYIR-YFPGHSKRVVALSMSPVDDTFISGSLD 128
+ + +V SS D R + ++ + V + SP ++ +LD
Sbjct: 178 HFNRDGSLIVSSS--YDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLD 235
Query: 129 KTIRLWDLRSPNC 141
T++LWD C
Sbjct: 236 NTLKLWDYSKGKC 248
Score = 47.8 bits (112), Expect = 1e-05
Identities = 32/123 (26%), Positives = 65/123 (52%), Gaps = 11/123 (8%)
Query: 19 ENSDKINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLYSKKYGVDLIRYTHAANTV 78
+++ ++ FSPNG+ +++++ D+++ L+D +GK +T K +Y AN
Sbjct: 212 DDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNE----KYCIFANFS 267
Query: 79 VYSSNKI----DDTIRYL-SLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSL--DKTI 131
V I +D + Y+ +L + ++ GH+ V++ + P ++ S +L DKTI
Sbjct: 268 VTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTI 327
Query: 132 RLW 134
+LW
Sbjct: 328 KLW 330
Score = 40.8 bits (94), Expect = 0.002
Identities = 36/175 (20%), Positives = 79/175 (45%), Gaps = 10/175 (5%)
Query: 8 LRSFRVAKVFRENSDKINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLY-SKKYGV 66
+++ + K +SD ++ F+ +G ++SSS D ++D G+ +TL V
Sbjct: 158 VKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPV 217
Query: 67 DLIRYTHAANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGH--SKRVVALSMSPVDDTFI- 123
++++ ++ ++ +D+T++ K ++ + GH K + + S +I
Sbjct: 218 SFVKFSPNGKYILAAT--LDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIV 275
Query: 124 SGSLDKTIRLWDLRS----PNCQGLMHLQGKPVCSFDPEGLIFAAGVNSEMVKLY 174
SGS D + +W+L++ QG + C + AA N + +KL+
Sbjct: 276 SGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 330
>gi|16554627 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 114 bits (285), Expect = 1e-25
Identities = 76/287 (26%), Positives = 139/287 (48%), Gaps = 25/287 (8%)
Query: 24 INCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLYSKKYGVDLIRYTHAANTVVYSSN 83
++ FSPNGE + SSS D I ++ +GK ++T+ K G+ + ++ +N +V +S+
Sbjct: 48 VSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASD 107
Query: 84 KIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKTIRLWDLRSPNCQG 143
D T++ + K ++ GHS V + +P + +SGS D+++R+WD+++ C
Sbjct: 108 --DKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLK 165
Query: 144 LMHLQGKPVCS--FDPEGLIFAAGVNSEMVKLYDLRSF--------DKGPFATFKMQYDR 193
+ PV + F+ +G + + + +++D S D P +F
Sbjct: 166 TLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSF------ 219
Query: 194 TCEWTGLKFSNDGKLILISTNGSFIRLIDAFKGVVMHTFGGYANSKAVTLEASFTPDSQF 253
+KFS +GK IL +T + ++L D KG + T+ G+ N K ++
Sbjct: 220 ------VKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKW 273
Query: 254 IMIGSEDGKIHVWNGESGIKVAVLDGKHTGPITCLQFNPKFMTFASA 300
I+ GSED +++WN ++ V L G HT + +P ASA
Sbjct: 274 IVSGSEDNLVYIWNLQTKEIVQKLQG-HTDVVISTACHPTENIIASA 319
Score = 50.4 bits (119), Expect = 2e-06
Identities = 31/133 (23%), Positives = 61/133 (45%), Gaps = 3/133 (2%)
Query: 10 SFRVAKVFRENSDKINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLYSKKYGVDLI 69
S + K + +S+ + C +F+P ++S S D+S+ ++D + GK +TL + V +
Sbjct: 118 SGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAV 177
Query: 70 RYTHAANTVVYSSNKIDDTIRYLSLHDNKYIR-YFPGHSKRVVALSMSPVDDTFISGSLD 128
+ + +V SS D R + ++ + V + SP ++ +LD
Sbjct: 178 HFNRDGSLIVSSS--YDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLD 235
Query: 129 KTIRLWDLRSPNC 141
T++LWD C
Sbjct: 236 NTLKLWDYSKGKC 248
Score = 47.8 bits (112), Expect = 1e-05
Identities = 32/123 (26%), Positives = 65/123 (52%), Gaps = 11/123 (8%)
Query: 19 ENSDKINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLYSKKYGVDLIRYTHAANTV 78
+++ ++ FSPNG+ +++++ D+++ L+D +GK +T K +Y AN
Sbjct: 212 DDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNE----KYCIFANFS 267
Query: 79 VYSSNKI----DDTIRYL-SLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSL--DKTI 131
V I +D + Y+ +L + ++ GH+ V++ + P ++ S +L DKTI
Sbjct: 268 VTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTI 327
Query: 132 RLW 134
+LW
Sbjct: 328 KLW 330
Score = 40.8 bits (94), Expect = 0.002
Identities = 36/175 (20%), Positives = 79/175 (45%), Gaps = 10/175 (5%)
Query: 8 LRSFRVAKVFRENSDKINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLY-SKKYGV 66
+++ + K +SD ++ F+ +G ++SSS D ++D G+ +TL V
Sbjct: 158 VKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPV 217
Query: 67 DLIRYTHAANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGH--SKRVVALSMSPVDDTFI- 123
++++ ++ ++ +D+T++ K ++ + GH K + + S +I
Sbjct: 218 SFVKFSPNGKYILAAT--LDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIV 275
Query: 124 SGSLDKTIRLWDLRS----PNCQGLMHLQGKPVCSFDPEGLIFAAGVNSEMVKLY 174
SGS D + +W+L++ QG + C + AA N + +KL+
Sbjct: 276 SGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 330
>gi|23199987 WD repeat domain 5B [Homo sapiens]
Length = 330
Score = 114 bits (285), Expect = 1e-25
Identities = 75/291 (25%), Positives = 142/291 (48%), Gaps = 25/291 (8%)
Query: 20 NSDKINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLYSKKYGVDLIRYTHAANTVV 79
+++ ++ FSPNGE + SSS D I+++ +GK ++TLY + + ++ ++ +V
Sbjct: 40 HTEAVSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSSRLV 99
Query: 80 YSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKTIRLWDLRSP 139
+S+ D T++ + K ++ GHS V + +P + ISGS D+T+++W++++
Sbjct: 100 SASD--DKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVKTG 157
Query: 140 NCQGLMHLQGKPVCS--FDPEGLIFAAGVNSEMVKLYDLRS--------FDKGPFATFKM 189
C + PV + F+ G + +G + +++D S D P +F
Sbjct: 158 KCLKTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWDAASGQCLKTLVDDDNPPVSF-- 215
Query: 190 QYDRTCEWTGLKFSNDGKLILISTNGSFIRLIDAFKGVVMHTFGGYANSKAVTLEASFTP 249
+KFS +GK IL +T + ++L D +G + T+ G+ N K
Sbjct: 216 ----------VKFSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGHKNEKYCIFANFSVT 265
Query: 250 DSQFIMIGSEDGKIHVWNGESGIKVAVLDGKHTGPITCLQFNPKFMTFASA 300
++I+ GSED +++WN ++ V L G HT + +P ASA
Sbjct: 266 GGKWIVSGSEDNLVYIWNLQTKEIVQKLQG-HTDVVISAACHPTENLIASA 315
Score = 50.4 bits (119), Expect = 2e-06
Identities = 33/142 (23%), Positives = 67/142 (47%), Gaps = 5/142 (3%)
Query: 1 MKLTDSVLRSFRVAKVFRENSDKINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLY 60
+KL D +RS + K + +S+ + C +F+P +IS S D+++ +++ + GK +TL
Sbjct: 107 LKLWD--VRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVKTGKCLKTLS 164
Query: 61 SKKYGVDLIRYTHAANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVA-LSMSPVD 119
+ V + + + + +V S D R + ++ V+ + SP
Sbjct: 165 AHSDPVSAVHFNCSGSLIV--SGSYDGLCRIWDAASGQCLKTLVDDDNPPVSFVKFSPNG 222
Query: 120 DTFISGSLDKTIRLWDLRSPNC 141
++ +LD T++LWD C
Sbjct: 223 KYILTATLDNTLKLWDYSRGRC 244
Score = 46.2 bits (108), Expect = 4e-05
Identities = 31/123 (25%), Positives = 64/123 (52%), Gaps = 11/123 (8%)
Query: 19 ENSDKINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLYSKKYGVDLIRYTHAANTV 78
+++ ++ FSPNG+ +++++ D+++ L+D G+ +T K +Y AN
Sbjct: 208 DDNPPVSFVKFSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGHKNE----KYCIFANFS 263
Query: 79 VYSSNKI----DDTIRYL-SLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSL--DKTI 131
V I +D + Y+ +L + ++ GH+ V++ + P ++ S +L DKTI
Sbjct: 264 VTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISAACHPTENLIASAALENDKTI 323
Query: 132 RLW 134
+LW
Sbjct: 324 KLW 326
>gi|61743926 F-box and WD repeat domain containing 7 isoform 3 [Homo
sapiens]
Length = 589
Score = 82.8 bits (203), Expect = 4e-16
Identities = 72/296 (24%), Positives = 130/296 (43%), Gaps = 23/296 (7%)
Query: 15 KVFRENSDK-INCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLYSKKYGVDLIRYTH 73
KV + + D I C F G ++S SDD+++ ++ GK RTL GV ++
Sbjct: 256 KVLKGHDDHVITCLQFC--GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGV----WSS 309
Query: 74 AANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKTIRL 133
+ S D T++ + + I GH+ V + + + +SGS D T+R+
Sbjct: 310 QMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLH--EKRVVSGSRDATLRV 367
Query: 134 WDLRSPNCQGLMHLQGKPVCSFDPEGLIFAAGVNSEMVKLYDLRSFDKGPFATFKMQYDR 193
WD+ + C ++ V +G +G MVK++D + + T + +R
Sbjct: 368 WDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPET--ETCLHTLQGHTNR 425
Query: 194 TCEWTGLKFSNDGKLILISTNGSFIRLIDAFKGVVMHTFGGYANSKAVTLEASFTPDSQF 253
L+F DG ++ + + IR+ D G +HT G+ + L +
Sbjct: 426 VYS---LQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQS-----LTSGMELKDNI 475
Query: 254 IMIGSEDGKIHVWNGESGIKVAVLDG--KHTGPITCLQFNPKFMTFASACSNMAFW 307
++ G+ D + +W+ ++G + L G KH +TCLQFN F+ +S + W
Sbjct: 476 LVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLW 531
Score = 42.4 bits (98), Expect = 5e-04
Identities = 36/160 (22%), Positives = 70/160 (43%), Gaps = 15/160 (9%)
Query: 24 INCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLYSKKYGVDLIRYTHAANTVVYSSN 83
+ C + +G V+S + D + ++D + TL V Y+ + + S
Sbjct: 386 VRCVQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRV----YSLQFDGIHVVSG 439
Query: 84 KIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKTIRLWDLRSPNC-- 141
+D +IR + I GH + + D+ +SG+ D T+++WD+++ C
Sbjct: 440 SLDTSIRVWDVETGNCIHTLTGHQSLTSGMELK--DNILVSGNADSTVKIWDIKTGQCLQ 497
Query: 142 --QGLMHLQGKPVC-SFDPEGLIFAAGVNSEMVKLYDLRS 178
QG Q C F+ +I ++ + VKL+DL++
Sbjct: 498 TLQGPNKHQSAVTCLQFNKNFVITSS--DDGTVKLWDLKT 535
Score = 28.9 bits (63), Expect = 6.2
Identities = 15/47 (31%), Positives = 27/47 (57%), Gaps = 2/47 (4%)
Query: 19 ENSDKINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLYSKKYG 65
++ + C F+ N VI+SSDD ++ L+D + G+ R L + + G
Sbjct: 504 KHQSAVTCLQFNKN--FVITSSDDGTVKLWDLKTGEFIRNLVTLESG 548
>gi|16117781 F-box and WD repeat domain containing 7 isoform 1 [Homo
sapiens]
Length = 707
Score = 82.8 bits (203), Expect = 4e-16
Identities = 72/296 (24%), Positives = 130/296 (43%), Gaps = 23/296 (7%)
Query: 15 KVFRENSDK-INCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLYSKKYGVDLIRYTH 73
KV + + D I C F G ++S SDD+++ ++ GK RTL GV ++
Sbjct: 374 KVLKGHDDHVITCLQFC--GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGV----WSS 427
Query: 74 AANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKTIRL 133
+ S D T++ + + I GH+ V + + + +SGS D T+R+
Sbjct: 428 QMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLH--EKRVVSGSRDATLRV 485
Query: 134 WDLRSPNCQGLMHLQGKPVCSFDPEGLIFAAGVNSEMVKLYDLRSFDKGPFATFKMQYDR 193
WD+ + C ++ V +G +G MVK++D + + T + +R
Sbjct: 486 WDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPET--ETCLHTLQGHTNR 543
Query: 194 TCEWTGLKFSNDGKLILISTNGSFIRLIDAFKGVVMHTFGGYANSKAVTLEASFTPDSQF 253
L+F DG ++ + + IR+ D G +HT G+ + L +
Sbjct: 544 VYS---LQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQS-----LTSGMELKDNI 593
Query: 254 IMIGSEDGKIHVWNGESGIKVAVLDG--KHTGPITCLQFNPKFMTFASACSNMAFW 307
++ G+ D + +W+ ++G + L G KH +TCLQFN F+ +S + W
Sbjct: 594 LVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLW 649
Score = 42.4 bits (98), Expect = 5e-04
Identities = 36/160 (22%), Positives = 70/160 (43%), Gaps = 15/160 (9%)
Query: 24 INCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLYSKKYGVDLIRYTHAANTVVYSSN 83
+ C + +G V+S + D + ++D + TL V Y+ + + S
Sbjct: 504 VRCVQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRV----YSLQFDGIHVVSG 557
Query: 84 KIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKTIRLWDLRSPNC-- 141
+D +IR + I GH + + D+ +SG+ D T+++WD+++ C
Sbjct: 558 SLDTSIRVWDVETGNCIHTLTGHQSLTSGMELK--DNILVSGNADSTVKIWDIKTGQCLQ 615
Query: 142 --QGLMHLQGKPVC-SFDPEGLIFAAGVNSEMVKLYDLRS 178
QG Q C F+ +I ++ + VKL+DL++
Sbjct: 616 TLQGPNKHQSAVTCLQFNKNFVITSS--DDGTVKLWDLKT 653
Score = 28.9 bits (63), Expect = 6.2
Identities = 15/47 (31%), Positives = 27/47 (57%), Gaps = 2/47 (4%)
Query: 19 ENSDKINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLYSKKYG 65
++ + C F+ N VI+SSDD ++ L+D + G+ R L + + G
Sbjct: 622 KHQSAVTCLQFNKN--FVITSSDDGTVKLWDLKTGEFIRNLVTLESG 666
>gi|16117779 F-box and WD repeat domain containing 7 isoform 2 [Homo
sapiens]
Length = 627
Score = 82.8 bits (203), Expect = 4e-16
Identities = 72/296 (24%), Positives = 130/296 (43%), Gaps = 23/296 (7%)
Query: 15 KVFRENSDK-INCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLYSKKYGVDLIRYTH 73
KV + + D I C F G ++S SDD+++ ++ GK RTL GV ++
Sbjct: 294 KVLKGHDDHVITCLQFC--GNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGV----WSS 347
Query: 74 AANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKTIRL 133
+ S D T++ + + I GH+ V + + + +SGS D T+R+
Sbjct: 348 QMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLH--EKRVVSGSRDATLRV 405
Query: 134 WDLRSPNCQGLMHLQGKPVCSFDPEGLIFAAGVNSEMVKLYDLRSFDKGPFATFKMQYDR 193
WD+ + C ++ V +G +G MVK++D + + T + +R
Sbjct: 406 WDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPET--ETCLHTLQGHTNR 463
Query: 194 TCEWTGLKFSNDGKLILISTNGSFIRLIDAFKGVVMHTFGGYANSKAVTLEASFTPDSQF 253
L+F DG ++ + + IR+ D G +HT G+ + L +
Sbjct: 464 VYS---LQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQS-----LTSGMELKDNI 513
Query: 254 IMIGSEDGKIHVWNGESGIKVAVLDG--KHTGPITCLQFNPKFMTFASACSNMAFW 307
++ G+ D + +W+ ++G + L G KH +TCLQFN F+ +S + W
Sbjct: 514 LVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLW 569
Score = 42.4 bits (98), Expect = 5e-04
Identities = 36/160 (22%), Positives = 70/160 (43%), Gaps = 15/160 (9%)
Query: 24 INCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLYSKKYGVDLIRYTHAANTVVYSSN 83
+ C + +G V+S + D + ++D + TL V Y+ + + S
Sbjct: 424 VRCVQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRV----YSLQFDGIHVVSG 477
Query: 84 KIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKTIRLWDLRSPNC-- 141
+D +IR + I GH + + D+ +SG+ D T+++WD+++ C
Sbjct: 478 SLDTSIRVWDVETGNCIHTLTGHQSLTSGMELK--DNILVSGNADSTVKIWDIKTGQCLQ 535
Query: 142 --QGLMHLQGKPVC-SFDPEGLIFAAGVNSEMVKLYDLRS 178
QG Q C F+ +I ++ + VKL+DL++
Sbjct: 536 TLQGPNKHQSAVTCLQFNKNFVITSS--DDGTVKLWDLKT 573
Score = 28.9 bits (63), Expect = 6.2
Identities = 15/47 (31%), Positives = 27/47 (57%), Gaps = 2/47 (4%)
Query: 19 ENSDKINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLYSKKYG 65
++ + C F+ N VI+SSDD ++ L+D + G+ R L + + G
Sbjct: 542 KHQSAVTCLQFNKN--FVITSSDDGTVKLWDLKTGEFIRNLVTLESG 586
>gi|20357529 guanine nucleotide-binding protein, beta-2 subunit
[Homo sapiens]
Length = 340
Score = 77.4 bits (189), Expect = 2e-14
Identities = 72/302 (23%), Positives = 118/302 (39%), Gaps = 53/302 (17%)
Query: 12 RVAKVFRENSDKINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLYSKKYGVDLIRY 71
R + R + KI + + ++S+S D ++++D + + V Y
Sbjct: 46 RTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAY 105
Query: 72 THAANTV----------VYSSNKIDDTIR----------YLS----LHDNKYIRY----- 102
+ N V +YS + +R YLS L DN+ I
Sbjct: 106 APSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTT 165
Query: 103 --------------FPGHSKRVVALSMSPVDDTFISGSLDKTIRLWDLRSPNCQG--LMH 146
F GHS V++LS++P TF+SG+ D +I+LWD+R C+ + H
Sbjct: 166 CALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGH 225
Query: 147 LQGKPVCSFDPEGLIFAAGVNSEMVKLYDLRSFDKGPFATFKMQYDR-TCEWTGLKFSND 205
+F P G F G + +L+DLR+ + +D C T + FS
Sbjct: 226 ESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQE----LLMYSHDNIICGITSVAFSRS 281
Query: 206 GKLILISTNGSFIRLIDAFKGVVMHTFGGYANSKAVTLEASFTPDSQFIMIGSEDGKIHV 265
G+L+L + + DA KG G+ N + T D + GS D + +
Sbjct: 282 GRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSC---LGVTDDGMAVATGSWDSFLKI 338
Query: 266 WN 267
WN
Sbjct: 339 WN 340
Score = 42.0 bits (97), Expect = 7e-04
Identities = 43/201 (21%), Positives = 78/201 (38%), Gaps = 8/201 (3%)
Query: 101 RYFPGHSKRVVALSMSPVDDTFISGSLDKTIRLWDLRSPNCQGLMHLQGKPV--CSFDPE 158
R GH ++ A+ +S S D + +WD + N + L+ V C++ P
Sbjct: 49 RTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPS 108
Query: 159 GLIFAAGVNSEMVKLYDLRSFDKGPFATFKMQYDRTCEWTGLKFSNDGKLILISTNGSFI 218
G A G + +Y L++ +G + T + +F +D + I+ S+ +
Sbjct: 109 GNFVACGGLDNICSIYSLKT-REGNVRVSRELPGHTGYLSCCRFLDDNQ-IITSSGDTTC 166
Query: 219 RLIDAFKGVVMHTFGGYANSKAVTLEASFTPDSQFIMIGSEDGKIHVWNGESGIKVAVLD 278
L D G F G++ + S PD + + G+ D I +W+ +
Sbjct: 167 ALWDIETGQQTVGFAGHSGD---VMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFI 223
Query: 279 GKHTGPITCLQFNPKFMTFAS 299
G H I + F P F +
Sbjct: 224 G-HESDINAVAFFPNGYAFTT 243
Score = 33.1 bits (74), Expect = 0.33
Identities = 30/138 (21%), Positives = 58/138 (42%), Gaps = 8/138 (5%)
Query: 1 MKLTDSVLRSFRVAKVFRENSDKINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLY 60
+KL D +R + F + IN F PNG + SDD + L+D + + + +Y
Sbjct: 208 IKLWD--VRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQ-ELLMY 264
Query: 61 SKK---YGVDLIRYTHAANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSP 117
S G+ + ++ + ++ + + I D + GH RV L ++
Sbjct: 265 SHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGV--LAGHDNRVSCLGVTD 322
Query: 118 VDDTFISGSLDKTIRLWD 135
+GS D +++W+
Sbjct: 323 DGMAVATGSWDSFLKIWN 340
>gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens]
Length = 369
Score = 77.0 bits (188), Expect = 2e-14
Identities = 59/258 (22%), Positives = 109/258 (42%), Gaps = 12/258 (4%)
Query: 17 FRENSDKINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLYSKKYGVDLIRYTHAAN 76
F + D + C +FSP+G + S S D ++ ++ + V + +
Sbjct: 19 FTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQ 78
Query: 77 TVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKTIRLWDL 136
+ V +S+ D T++ + H K++ H V SP +S S DKT++LWD
Sbjct: 79 SFVTASD--DKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDK 136
Query: 137 RSPNCQGLMHLQGKPV--CSFDPEGLIFAAGVNSEMVKLYDLRSFDKGPFATFKMQYDRT 194
S C G V F P G AA VK++D+R+ + +
Sbjct: 137 SSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRT-----HRLLQHYQLHS 191
Query: 195 CEWTGLKFSNDGKLILISTNGSFIRLIDAFKGVVMHTFGGYANSKAVTLEASFTPDSQFI 254
GL F G ++ +++ S ++++D +G +++T G+ A T+ +F+ ++
Sbjct: 192 AAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGH-QGPATTV--AFSRTGEYF 248
Query: 255 MIGSEDGKIHVWNGESGI 272
G D ++ VW I
Sbjct: 249 ASGGSDEQVMVWKSNFDI 266
Score = 33.9 bits (76), Expect = 0.19
Identities = 15/53 (28%), Positives = 32/53 (60%)
Query: 8 LRSFRVAKVFRENSDKINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLY 60
+R+ R+ + ++ +S +N F P+G +I++S D ++ + D EG+ TL+
Sbjct: 178 VRTHRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLH 230
>gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens]
Length = 359
Score = 77.0 bits (188), Expect = 2e-14
Identities = 59/258 (22%), Positives = 109/258 (42%), Gaps = 12/258 (4%)
Query: 17 FRENSDKINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLYSKKYGVDLIRYTHAAN 76
F + D + C +FSP+G + S S D ++ ++ + V + +
Sbjct: 57 FTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQ 116
Query: 77 TVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKTIRLWDL 136
+ V +S+ D T++ + H K++ H V SP +S S DKT++LWD
Sbjct: 117 SFVTASD--DKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDK 174
Query: 137 RSPNCQGLMHLQGKPV--CSFDPEGLIFAAGVNSEMVKLYDLRSFDKGPFATFKMQYDRT 194
S C G V F P G AA VK++D+R+ + +
Sbjct: 175 SSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRT-----HRLLQHYQLHS 229
Query: 195 CEWTGLKFSNDGKLILISTNGSFIRLIDAFKGVVMHTFGGYANSKAVTLEASFTPDSQFI 254
GL F G ++ +++ S ++++D +G +++T G+ A T+ +F+ ++
Sbjct: 230 AAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGH-QGPATTV--AFSRTGEYF 286
Query: 255 MIGSEDGKIHVWNGESGI 272
G D ++ VW I
Sbjct: 287 ASGGSDEQVMVWKSNFDI 304
Score = 53.5 bits (127), Expect = 2e-07
Identities = 52/234 (22%), Positives = 86/234 (36%), Gaps = 19/234 (8%)
Query: 76 NTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKTIRLWD 135
NT +S +D + + F GH V ++ SP SGS DKT+R+W
Sbjct: 30 NTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIW- 88
Query: 136 LRSPNCQG-----LMHLQGKPVCSFDPEGLIFAAGVNSEMVKLYDLRSFDKGPFATFKMQ 190
PN +G H F +G F + + VK++ F
Sbjct: 89 --VPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHR------QKFLFS 140
Query: 191 YDRTCEWTG-LKFSNDGKLILISTNGSFIRLIDAFKGVVMHTFGGYANSKAVTLEASFTP 249
+ W KFS DG+LI+ +++ ++L D +H+ Y F P
Sbjct: 141 LSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHS---YCEHGGFVTYVDFHP 197
Query: 250 DSQFIMIGSEDGKIHVWNGESGIKVAVLDGKHTGPITCLQFNPKFMTFASACSN 303
I D + VW+ + ++ H+ + L F+P +A S+
Sbjct: 198 SGTCIAAAGMDNTVKVWDVRTH-RLLQHYQLHSAAVNGLSFHPSGNYLITASSD 250
Score = 51.6 bits (122), Expect = 9e-07
Identities = 43/202 (21%), Positives = 87/202 (43%), Gaps = 11/202 (5%)
Query: 101 RYFPGHSKRVVALSMSPVDDTFISGSLDKTIRLWDLR--SPNCQGLMHLQGKPVCSFDPE 158
R+F GH V + S SGS+D + +W ++ S + H +F P
Sbjct: 13 RHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPS 72
Query: 159 GLIFAAGVNSEMVKLYDLRSFDKGPFATFKMQYDRTCEWTGLKFSNDGKLILISTNGSFI 218
G + A+G + V+++ KG F+ T + F +DG+ + +++ +
Sbjct: 73 GHLLASGSRDKTVRIWVPNV--KGESTVFRA---HTATVRSVHFCSDGQSFVTASDDKTV 127
Query: 219 RLIDAFKGVVMHTFGGYANSKAVTLEASFTPDSQFIMIGSEDGKIHVWNGESGIKVAVLD 278
++ + + + + N A F+PD + I+ S+D + +W+ +S +
Sbjct: 128 KVWATHRQKFLFSLSQHINWVRC---AKFSPDGRLIVSASDDKTVKLWD-KSSRECVHSY 183
Query: 279 GKHTGPITCLQFNPKFMTFASA 300
+H G +T + F+P A+A
Sbjct: 184 CEHGGFVTYVDFHPSGTCIAAA 205
Score = 33.9 bits (76), Expect = 0.19
Identities = 15/53 (28%), Positives = 32/53 (60%)
Query: 8 LRSFRVAKVFRENSDKINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLY 60
+R+ R+ + ++ +S +N F P+G +I++S D ++ + D EG+ TL+
Sbjct: 216 VRTHRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLH 268
>gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens]
Length = 407
Score = 77.0 bits (188), Expect = 2e-14
Identities = 59/258 (22%), Positives = 109/258 (42%), Gaps = 12/258 (4%)
Query: 17 FRENSDKINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLYSKKYGVDLIRYTHAAN 76
F + D + C +FSP+G + S S D ++ ++ + V + +
Sbjct: 57 FTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQ 116
Query: 77 TVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKTIRLWDL 136
+ V +S+ D T++ + H K++ H V SP +S S DKT++LWD
Sbjct: 117 SFVTASD--DKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDK 174
Query: 137 RSPNCQGLMHLQGKPV--CSFDPEGLIFAAGVNSEMVKLYDLRSFDKGPFATFKMQYDRT 194
S C G V F P G AA VK++D+R+ + +
Sbjct: 175 SSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRT-----HRLLQHYQLHS 229
Query: 195 CEWTGLKFSNDGKLILISTNGSFIRLIDAFKGVVMHTFGGYANSKAVTLEASFTPDSQFI 254
GL F G ++ +++ S ++++D +G +++T G+ A T+ +F+ ++
Sbjct: 230 AAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGH-QGPATTV--AFSRTGEYF 286
Query: 255 MIGSEDGKIHVWNGESGI 272
G D ++ VW I
Sbjct: 287 ASGGSDEQVMVWKSNFDI 304
Score = 53.5 bits (127), Expect = 2e-07
Identities = 52/234 (22%), Positives = 86/234 (36%), Gaps = 19/234 (8%)
Query: 76 NTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKTIRLWD 135
NT +S +D + + F GH V ++ SP SGS DKT+R+W
Sbjct: 30 NTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIW- 88
Query: 136 LRSPNCQG-----LMHLQGKPVCSFDPEGLIFAAGVNSEMVKLYDLRSFDKGPFATFKMQ 190
PN +G H F +G F + + VK++ F
Sbjct: 89 --VPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHR------QKFLFS 140
Query: 191 YDRTCEWTG-LKFSNDGKLILISTNGSFIRLIDAFKGVVMHTFGGYANSKAVTLEASFTP 249
+ W KFS DG+LI+ +++ ++L D +H+ Y F P
Sbjct: 141 LSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHS---YCEHGGFVTYVDFHP 197
Query: 250 DSQFIMIGSEDGKIHVWNGESGIKVAVLDGKHTGPITCLQFNPKFMTFASACSN 303
I D + VW+ + ++ H+ + L F+P +A S+
Sbjct: 198 SGTCIAAAGMDNTVKVWDVRTH-RLLQHYQLHSAAVNGLSFHPSGNYLITASSD 250
Score = 51.6 bits (122), Expect = 9e-07
Identities = 43/202 (21%), Positives = 87/202 (43%), Gaps = 11/202 (5%)
Query: 101 RYFPGHSKRVVALSMSPVDDTFISGSLDKTIRLWDLR--SPNCQGLMHLQGKPVCSFDPE 158
R+F GH V + S SGS+D + +W ++ S + H +F P
Sbjct: 13 RHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPS 72
Query: 159 GLIFAAGVNSEMVKLYDLRSFDKGPFATFKMQYDRTCEWTGLKFSNDGKLILISTNGSFI 218
G + A+G + V+++ KG F+ T + F +DG+ + +++ +
Sbjct: 73 GHLLASGSRDKTVRIWVPNV--KGESTVFRA---HTATVRSVHFCSDGQSFVTASDDKTV 127
Query: 219 RLIDAFKGVVMHTFGGYANSKAVTLEASFTPDSQFIMIGSEDGKIHVWNGESGIKVAVLD 278
++ + + + + N A F+PD + I+ S+D + +W+ +S +
Sbjct: 128 KVWATHRQKFLFSLSQHINWVRC---AKFSPDGRLIVSASDDKTVKLWD-KSSRECVHSY 183
Query: 279 GKHTGPITCLQFNPKFMTFASA 300
+H G +T + F+P A+A
Sbjct: 184 CEHGGFVTYVDFHPSGTCIAAA 205
Score = 33.9 bits (76), Expect = 0.19
Identities = 15/53 (28%), Positives = 32/53 (60%)
Query: 8 LRSFRVAKVFRENSDKINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLY 60
+R+ R+ + ++ +S +N F P+G +I++S D ++ + D EG+ TL+
Sbjct: 216 VRTHRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLH 268
>gi|70909324 sperm associated antigen 16 isoform 1 [Homo sapiens]
Length = 631
Score = 77.0 bits (188), Expect = 2e-14
Identities = 59/247 (23%), Positives = 107/247 (43%), Gaps = 25/247 (10%)
Query: 29 FSPNGETVISSSDDDSIVLYDCQEGKPKRTLYSKKYGVDLIRYTHAANTVVYSSNKIDDT 88
F P+G+ + +SS D ++ L+D +G T V + N V SS +D T
Sbjct: 402 FHPSGDKLATSSGDTTVKLWDLCKGDCILTFEGHSRAVWSCTWHSCGNFVASSS--LDKT 459
Query: 89 IRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKTIRLWDLRSPNCQGLM--H 146
+ ++ + GH+ V ++ P +T ++ S DKT+ +WD R+ C+ + H
Sbjct: 460 SKIWDVNSERCRCTLYGHTDSVNSIEFFPFSNTLLTSSADKTLSIWDARTGICEQSLYGH 519
Query: 147 LQGKPVCSFDPEGLIFAAGVNSEMVKLYDLR------SFDKGPFATFKMQYDRTCEWTGL 200
+ FDP G + A+ + KL+D R S D GP ++ +D
Sbjct: 520 MHSINDAIFDPRGHMIASCDACGVTKLWDFRKLLPIVSIDIGPSPGNEVNFD-------- 571
Query: 201 KFSNDGKLILISTNGSFIRLIDAFKGVVMHTFGGYANSKAVTLEASFTPDSQFIMIGSED 260
+ G+++ ++ I L+D G + H G+ N + F+ D + + G D
Sbjct: 572 ---SSGRVLAQASGNGVIHLLDLKSGEI-HKLMGHENEAHTVV---FSHDGEILFSGGSD 624
Query: 261 GKIHVWN 267
G + W+
Sbjct: 625 GTVRTWS 631
Score = 43.9 bits (102), Expect = 2e-04
Identities = 59/221 (26%), Positives = 81/221 (36%), Gaps = 23/221 (10%)
Query: 96 DNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKTIRLWD-LRSPNCQGLM----HLQGK 150
D K F H V +SM P D +S D RLW L P C L+ H
Sbjct: 341 DYKLKNIFRLHELPVSCVSMQPHKDILVSCGED---RLWKVLGLPKCNVLLTGFGHTDWL 397
Query: 151 PVCSFDPEGLIFAAGVNSEMVKLYDLRSFDKGPFATFK--MQYDRTCEWTGLKFSNDGKL 208
C F P G A VKL+DL D TF+ + +C W + G
Sbjct: 398 SDCCFHPSGDKLATSSGDTTVKLWDLCKGD--CILTFEGHSRAVWSCTW-----HSCGNF 450
Query: 209 ILISTNGSFIRLIDAFKGVVMHTFGGYANSKAVTLEASFTPDSQFIMIGSEDGKIHVWNG 268
+ S+ ++ D T G+ +S F P S ++ S D + +W+
Sbjct: 451 VASSSLDKTSKIWDVNSERCRCTLYGHTDS---VNSIEFFPFSNTLLTSSADKTLSIWDA 507
Query: 269 ESGIKVAVLDGKHTGPITCLQFNPKFMTFAS--ACSNMAFW 307
+GI L G H I F+P+ AS AC W
Sbjct: 508 RTGICEQSLYG-HMHSINDAIFDPRGHMIASCDACGVTKLW 547
Score = 33.5 bits (75), Expect = 0.25
Identities = 12/48 (25%), Positives = 30/48 (62%)
Query: 20 NSDKINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLYSKKYGVD 67
++D +N +F P T+++SS D ++ ++D + G +++LY + ++
Sbjct: 477 HTDSVNSIEFFPFSNTLLTSSADKTLSIWDARTGICEQSLYGHMHSIN 524
>gi|11055998 guanine nucleotide-binding protein, beta-4 subunit
[Homo sapiens]
Length = 340
Score = 76.6 bits (187), Expect = 3e-14
Identities = 65/246 (26%), Positives = 104/246 (42%), Gaps = 17/246 (6%)
Query: 29 FSPNGETVISSSDDDSIVLYDCQ--EGKPK--RTLYSKKYGVDLIRYTHAANTVVYSSNK 84
++P+G V D+ +Y+ + EG + R L + R+ + V S
Sbjct: 105 YAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDSQIVTSSG-- 162
Query: 85 IDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKTIRLWDLRSPNCQGL 144
D T + + F GHS V++LS+SP TF+SG+ D + +LWD+R C+
Sbjct: 163 -DTTCALWDIETAQQTTTFTGHSGDVMSLSLSPDMRTFVSGACDASSKLWDIRDGMCRQS 221
Query: 145 M--HLQGKPVCSFDPEGLIFAAGVNSEMVKLYDLRSFDKGPFATFKMQYDR-TCEWTGLK 201
H+ SF P G FA G + +L+DLR+ + +D C T +
Sbjct: 222 FTGHVSDINAVSFFPNGYAFATGSDDATCRLFDLRADQE----LLLYSHDNIICGITSVA 277
Query: 202 FSNDGKLILISTNGSFIRLIDAFKGVVMHTFGGYANSKAVTLEASFTPDSQFIMIGSEDG 261
FS G+L+L + + D KG G+ N + T D + GS D
Sbjct: 278 FSKSGRLLLAGYDDFNCNVWDTLKGDRAGVLAGHDNRVSC---LGVTDDGMAVATGSWDS 334
Query: 262 KIHVWN 267
+ +WN
Sbjct: 335 FLRIWN 340
Score = 44.3 bits (103), Expect = 1e-04
Identities = 49/227 (21%), Positives = 93/227 (40%), Gaps = 13/227 (5%)
Query: 75 ANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKTIRLW 134
A V +SN D++ + + + +R GH ++ A+ +S S D + +W
Sbjct: 28 ATLVQITSNM--DSVGRIQMRTRRTLR---GHLAKIYAMHWGYDSRLLVSASQDGKLIIW 82
Query: 135 DLRSPNCQGLMHLQGKPV--CSFDPEGLIFAAGVNSEMVKLYDLRSFDKGPFATFKMQYD 192
D + N + L+ V C++ P G A G + +Y+L++ +G +
Sbjct: 83 DSYTTNKMHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKT-REGNVRVSRELPG 141
Query: 193 RTCEWTGLKFSNDGKLILISTNGSFIRLIDAFKGVVMHTFGGYANSKAVTLEASFTPDSQ 252
T + +F +D + I+ S+ + L D TF G++ + S +PD +
Sbjct: 142 HTGYLSCCRFLDDSQ-IVTSSGDTTCALWDIETAQQTTTFTGHSGD---VMSLSLSPDMR 197
Query: 253 FIMIGSEDGKIHVWNGESGIKVAVLDGKHTGPITCLQFNPKFMTFAS 299
+ G+ D +W+ G+ G H I + F P FA+
Sbjct: 198 TFVSGACDASSKLWDIRDGMCRQSFTG-HVSDINAVSFFPNGYAFAT 243
Score = 33.5 bits (75), Expect = 0.25
Identities = 27/122 (22%), Positives = 51/122 (41%), Gaps = 6/122 (4%)
Query: 17 FRENSDKINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLYSKK---YGVDLIRYTH 73
F + IN F PNG + SDD + L+D + + + LYS G+ + ++
Sbjct: 222 FTGHVSDINAVSFFPNGYAFATGSDDATCRLFDLRADQ-ELLLYSHDNIICGITSVAFSK 280
Query: 74 AANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKTIRL 133
+ ++ + + + D + GH RV L ++ +GS D +R+
Sbjct: 281 SGRLLLAGYDDFNCNVWDTLKGDRAGV--LAGHDNRVSCLGVTDDGMAVATGSWDSFLRI 338
Query: 134 WD 135
W+
Sbjct: 339 WN 340
Score = 29.6 bits (65), Expect = 3.6
Identities = 20/87 (22%), Positives = 40/87 (45%), Gaps = 6/87 (6%)
Query: 201 KFSNDGKLILISTNGSFIRLIDAFKGVVMHTFGGYANSKAVTLEASFTPDSQFIMIGSED 260
K ND L+ I++N +D+ + M T A + DS+ ++ S+D
Sbjct: 23 KACNDATLVQITSN------MDSVGRIQMRTRRTLRGHLAKIYAMHWGYDSRLLVSASQD 76
Query: 261 GKIHVWNGESGIKVAVLDGKHTGPITC 287
GK+ +W+ + K+ + + + +TC
Sbjct: 77 GKLIIWDSYTTNKMHAIPLRSSWVMTC 103
>gi|32189425 WD repeat domain 69 [Homo sapiens]
Length = 415
Score = 76.3 bits (186), Expect = 3e-14
Identities = 71/296 (23%), Positives = 126/296 (42%), Gaps = 16/296 (5%)
Query: 2 KLTDSVLRSFRVAKVFRENSDKINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLYS 61
KL + +F + KV + + + + +G I+ S D + L+D G+ TL
Sbjct: 73 KLGQNSNHTFYLFKVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEG 132
Query: 62 KKYGVDLIRYTHAANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDT 121
+ V I + + + ++ D T + S+ K F GH+ +V LS +P
Sbjct: 133 HRNVVYAIAFNNPYGDKI-ATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTL 191
Query: 122 FISGSLDKTIRLWDLRSPNCQGLMHLQGKPV----CSFDPEGLIFAAGVNSEMVKLYDLR 177
+GS+D T +LWD++ N + + L+G SF+ G G V ++D
Sbjct: 192 VATGSMDTTAKLWDIQ--NGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDAD 249
Query: 178 SFDKGPFATFKMQYDRTCEWTGLKFSNDGKLILISTNGSFIRLIDAFKGVVMHTFGGYAN 237
+ K + E + F+ D LIL + +L DA G + T G+ +
Sbjct: 250 TGRK-----VNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDD 304
Query: 238 SKAVTLEASFTPDSQFIMIGSEDGKIHVWNGESGIKVAVLDGKHTGPITCLQFNPK 293
L++ F + I S DG +++ + +A L+G H G I+ + FNP+
Sbjct: 305 E---ILDSCFDYTGKLIATASADGTARIFSAATRKCIAKLEG-HEGEISKISFNPQ 356
Score = 68.9 bits (167), Expect = 5e-12
Identities = 58/266 (21%), Positives = 113/266 (42%), Gaps = 13/266 (4%)
Query: 30 SPNGETVISSSDDDSIVLYDCQEGKPKRTLYSKKYGVDLIRYTHAANTVVYSSNKIDDTI 89
+P G+ + + S D + L+ + GK T + + +++ + + + ++ +D T
Sbjct: 144 NPYGDKIATGSFDKTCKLWSVETGKCYHTF--RGHTAEIVCLSFNPQSTLVATGSMDTTA 201
Query: 90 RYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKTIRLWDLRSPNCQGLM--HL 147
+ + + + + GHS +++LS + D I+GS D T+ +WD + ++ H
Sbjct: 202 KLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHC 261
Query: 148 QGKPVCSFDPEGLIFAAGVNSEMVKLYDLRSFDKGPFATFKMQYDRTCEWTGLKFSNDGK 207
SF+ + + G + KL+D + G +D E F GK
Sbjct: 262 AEISSASFNWDCSLILTGSMDKTCKLWDATN---GKCVATLTGHDD--EILDSCFDYTGK 316
Query: 208 LILISTNGSFIRLIDAFKGVVMHTFGGYANSKAVTLEASFTPDSQFIMIGSEDGKIHVWN 267
LI ++ R+ A + G+ + + SF P ++ GS D +W+
Sbjct: 317 LIATASADGTARIFSAATRKCIAKLEGHEGEIS---KISFNPQGNHLLTGSSDKTARIWD 373
Query: 268 GESGIKVAVLDGKHTGPITCLQFNPK 293
++G + VL+G HT I FN K
Sbjct: 374 AQTGQCLQVLEG-HTDEIFSCAFNYK 398
Score = 55.1 bits (131), Expect = 8e-08
Identities = 54/214 (25%), Positives = 93/214 (43%), Gaps = 18/214 (8%)
Query: 84 KIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKTIRLWDLRSPNCQG 143
++ + + S H + H + ++++ FI+GS D+T +LWD S +
Sbjct: 69 RLQEKLGQNSNHTFYLFKVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASG--EE 126
Query: 144 LMHLQGK-----PVCSFDPEGLIFAAGVNSEMVKLYDLRSFDKGP-FATFKMQYDRTCEW 197
L L+G + +P G A G + KL+ S + G + TF+ T E
Sbjct: 127 LNTLEGHRNVVYAIAFNNPYGDKIATGSFDKTCKLW---SVETGKCYHTFR---GHTAEI 180
Query: 198 TGLKFSNDGKLILISTNGSFIRLIDAFKGVVMHTFGGYANSKAVTLEASFTPDSQFIMIG 257
L F+ L+ + + +L D G ++T G++ A + SF I+ G
Sbjct: 181 VCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHS---AEIISLSFNTSGDRIITG 237
Query: 258 SEDGKIHVWNGESGIKVAVLDGKHTGPITCLQFN 291
S D + VW+ ++G KV +L G H I+ FN
Sbjct: 238 SFDHTVVVWDADTGRKVNILIG-HCAEISSASFN 270
Score = 50.8 bits (120), Expect = 2e-06
Identities = 36/154 (23%), Positives = 67/154 (43%), Gaps = 4/154 (2%)
Query: 23 KINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLYSKKYGVDLIRYTHAANTVVYSS 82
+I+ F+ + +++ S D + L+D GK TL + + + + +S
Sbjct: 263 EISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATAS 322
Query: 83 NKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKTIRLWDLRSPNCQ 142
D T R S K I GH + +S +P + ++GS DKT R+WD ++ C
Sbjct: 323 --ADGTARIFSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCL 380
Query: 143 GLM--HLQGKPVCSFDPEGLIFAAGVNSEMVKLY 174
++ H C+F+ +G I G +++
Sbjct: 381 QVLEGHTDEIFSCAFNYKGNIVITGSKDNTCRIW 414
>gi|124256480 APG16 autophagy 16-like isoform 1 [Homo sapiens]
Length = 607
Score = 75.5 bits (184), Expect = 6e-14
Identities = 61/281 (21%), Positives = 124/281 (44%), Gaps = 14/281 (4%)
Query: 16 VFRENSDKINCFDFSPNGETVISSSDDDSIVLYDC--QEGKPKRTLYSKKYGVDLIRYTH 73
VF + ++N FSP + + D + L++ ++ + K +L G+ I +
Sbjct: 317 VFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDS 376
Query: 74 AANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKTIRL 133
A + ++ +SN D R ++ D + GHS +V++ + +SGS D+T++L
Sbjct: 377 AGSYLLAASN--DFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKL 434
Query: 134 WDLRSPNCQGLMHLQGKPVCSFDPEGLIFAAGVNSEMVKLYDLRSFDKGPFATFKMQYDR 193
WDLRS C + G +G + ++ +D+RS + + +
Sbjct: 435 WDLRSKVCIKTV-FAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRS------ESIVREMEL 487
Query: 194 TCEWTGLKFSNDGKLILISTNGSFIRLIDAFKGVVMHTFG--GYANSKAVTLEASFTPDS 251
+ T L + + +L + +++ID + TF G+ T F+PD
Sbjct: 488 LGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWT-RVVFSPDG 546
Query: 252 QFIMIGSEDGKIHVWNGESGIKVAVLDGKHTGPITCLQFNP 292
++ GS +G +++W+ +G VL +H+ I + ++P
Sbjct: 547 SYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSP 587
Score = 34.3 bits (77), Expect = 0.15
Identities = 34/161 (21%), Positives = 64/161 (39%), Gaps = 12/161 (7%)
Query: 11 FRVAKVFRENSDKINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLYSKKYGVDLIR 70
+R+ +S K+ F + ++S S D ++ L+D + +T+++ D++
Sbjct: 398 YRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIV- 456
Query: 71 YTHAANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKT 130
S D IR+ + +R K + AL ++P +S S D
Sbjct: 457 ----CTEQCVMSGHFDKKIRFWDIRSESIVREMELLGK-ITALDLNPERTELLSCSRDDL 511
Query: 131 IRLWDLRSPNCQGLMHLQGKPVCS------FDPEGLIFAAG 165
+++ DLR+ + G S F P+G AAG
Sbjct: 512 LKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAG 552
>gi|124256478 APG16 autophagy 16-like isoform 2 [Homo sapiens]
Length = 588
Score = 75.5 bits (184), Expect = 6e-14
Identities = 61/281 (21%), Positives = 124/281 (44%), Gaps = 14/281 (4%)
Query: 16 VFRENSDKINCFDFSPNGETVISSSDDDSIVLYDC--QEGKPKRTLYSKKYGVDLIRYTH 73
VF + ++N FSP + + D + L++ ++ + K +L G+ I +
Sbjct: 298 VFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDS 357
Query: 74 AANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKTIRL 133
A + ++ +SN D R ++ D + GHS +V++ + +SGS D+T++L
Sbjct: 358 AGSYLLAASN--DFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKL 415
Query: 134 WDLRSPNCQGLMHLQGKPVCSFDPEGLIFAAGVNSEMVKLYDLRSFDKGPFATFKMQYDR 193
WDLRS C + G +G + ++ +D+RS + + +
Sbjct: 416 WDLRSKVCIKTV-FAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRS------ESIVREMEL 468
Query: 194 TCEWTGLKFSNDGKLILISTNGSFIRLIDAFKGVVMHTFG--GYANSKAVTLEASFTPDS 251
+ T L + + +L + +++ID + TF G+ T F+PD
Sbjct: 469 LGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWT-RVVFSPDG 527
Query: 252 QFIMIGSEDGKIHVWNGESGIKVAVLDGKHTGPITCLQFNP 292
++ GS +G +++W+ +G VL +H+ I + ++P
Sbjct: 528 SYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSP 568
Score = 34.3 bits (77), Expect = 0.15
Identities = 34/161 (21%), Positives = 64/161 (39%), Gaps = 12/161 (7%)
Query: 11 FRVAKVFRENSDKINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLYSKKYGVDLIR 70
+R+ +S K+ F + ++S S D ++ L+D + +T+++ D++
Sbjct: 379 YRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIV- 437
Query: 71 YTHAANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKT 130
S D IR+ + +R K + AL ++P +S S D
Sbjct: 438 ----CTEQCVMSGHFDKKIRFWDIRSESIVREMELLGK-ITALDLNPERTELLSCSRDDL 492
Query: 131 IRLWDLRSPNCQGLMHLQGKPVCS------FDPEGLIFAAG 165
+++ DLR+ + G S F P+G AAG
Sbjct: 493 LKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAG 533
>gi|113865883 WD repeat domain 38 [Homo sapiens]
Length = 314
Score = 70.1 bits (170), Expect = 2e-12
Identities = 65/281 (23%), Positives = 113/281 (40%), Gaps = 14/281 (4%)
Query: 12 RVAKVFRENSDKINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLYSKKYGVDLIRY 71
R K F ++ ++N FSP+G+ +++ S+D + ++ + G+ L V R+
Sbjct: 12 RRVKFFGQHGGEVNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCRF 71
Query: 72 THAANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKTI 131
+ + +++S D T+R + K +R GH + V +S SP SG DK +
Sbjct: 72 SPDGH--LFASASCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRV 129
Query: 132 RLWDLRSPNCQGLM--HLQGKPVCSFDPEGLIFAAGVNSEMVKLYDLRSFDKGPFATFKM 189
LWD++S L+ H F P A G V ++DLR P + +
Sbjct: 130 MLWDVQSGQMLRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVHIWDLRMVT--PAVSHQA 187
Query: 190 QYDRTCEWTGLKFSNDGKLILISTNGSFIRLIDAFKGVVMHTFGGYANSKAVTLEASFTP 249
+ + L +S G L +GS+ + I +K +F+P
Sbjct: 188 LEGHSANISCLCYSASGLL----ASGSWDKTIHIWKPTTSSLLIQLKGHVTWVKSIAFSP 243
Query: 250 DSQFIMIGSEDGKIHVWNGESG----IKVAVLDGKHTGPIT 286
D ++ + VW+ +G VLD HT T
Sbjct: 244 DELWLASAGYSRMVKVWDCNTGKCLETLKGVLDVAHTCAFT 284
Score = 50.1 bits (118), Expect = 3e-06
Identities = 29/68 (42%), Positives = 38/68 (55%), Gaps = 7/68 (10%)
Query: 233 GGYANSKAVTLEASFTPDSQFIMIGSEDGKIHVWNGESGIKVAVLDGKHTGPITCLQFNP 292
GG NS A F+PD Q ++ GSEDG ++ W SG + L G HTGP+ +F+P
Sbjct: 21 GGEVNSSA------FSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGG-HTGPVKFCRFSP 73
Query: 293 KFMTFASA 300
FASA
Sbjct: 74 DGHLFASA 81
>gi|11321585 guanine nucleotide-binding protein, beta-1 subunit
[Homo sapiens]
Length = 340
Score = 70.1 bits (170), Expect = 2e-12
Identities = 53/194 (27%), Positives = 84/194 (43%), Gaps = 10/194 (5%)
Query: 76 NTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKTIRLWD 135
N +V SS D T + + F GH+ V++LS++P F+SG+ D + +LWD
Sbjct: 155 NQIVTSSG--DTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWD 212
Query: 136 LRSPNCQGLM--HLQGKPVCSFDPEGLIFAAGVNSEMVKLYDLRSFDKGPFATFKMQYDR 193
+R C+ H F P G FA G + +L+DLR+ + T+ +
Sbjct: 213 VREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQE--LMTYSHD-NI 269
Query: 194 TCEWTGLKFSNDGKLILISTNGSFIRLIDAFKGVVMHTFGGYANSKAVTLEASFTPDSQF 253
C T + FS G+L+L + + DA K G+ N + T D
Sbjct: 270 ICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSC---LGVTDDGMA 326
Query: 254 IMIGSEDGKIHVWN 267
+ GS D + +WN
Sbjct: 327 VATGSWDSFLKIWN 340
Score = 53.5 bits (127), Expect = 2e-07
Identities = 47/214 (21%), Positives = 100/214 (46%), Gaps = 14/214 (6%)
Query: 12 RVAKVFRENSDKINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLYSKKYGVDLIRY 71
RV++ ++ ++C F + + +++SS D + L+D + G+ + T ++ G D++
Sbjct: 134 RVSRELAGHTGYLSCCRFLDDNQ-IVTSSGDTTCALWDIETGQ-QTTTFTGHTG-DVMSL 190
Query: 72 THAANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKTI 131
+ A +T ++ S D + + + + + F GH + A+ P + F +GS D T
Sbjct: 191 SLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATC 250
Query: 132 RLWDLRSPNCQGLMHLQGKPVC-----SFDPEGLIFAAGVNSEMVKLYDLRSFDKGPFAT 186
RL+DLR+ + + + +C SF G + AG + ++D D+ A
Sbjct: 251 RLFDLRADQ-ELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADR---AG 306
Query: 187 FKMQYDRTCEWTGLKFSNDGKLILISTNGSFIRL 220
+D G+ ++DG + + SF+++
Sbjct: 307 VLAGHDNRVSCLGV--TDDGMAVATGSWDSFLKI 338
>gi|199559532 Abelson helper integration site 1 isoform b [Homo
sapiens]
Length = 1053
Score = 69.3 bits (168), Expect = 4e-12
Identities = 77/299 (25%), Positives = 128/299 (42%), Gaps = 28/299 (9%)
Query: 26 CFDFSPNGETVIS---SSDDDSIVLYDCQEGKPKRTLYSKKYGVDLIRYTHAANTVVYSS 82
C DFS NG + + S D I+LY+ G+ R L + + ++ + ++ SS
Sbjct: 614 CLDFSHNGRILAAACASRDGYPIILYEIPSGRFMRELCGHLNIIYDLSWSKDDHYILTSS 673
Query: 83 NKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKTIRLWDLRSPNCQ 142
+ I +++ R P S A V + ++G D IR+W +
Sbjct: 674 SDGTARIWKNEINNTNTFRVLPHPSFVYTAKFHPAVRELVVTGCYDSMIRIWKVEMREDS 733
Query: 143 GLM------HLQGKPVCSFDPEGLIFAAG-------VNSEMVKLYDLRSFDKGPFATFKM 189
++ H FD EG +G V + VK+ DL T
Sbjct: 734 AILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNTYVKINDLEH--SVHHWTINK 791
Query: 190 QYDRTCEWTGLKFSN-----DGKLILISTNGSFIRLIDAFKGVVMHTFGGYANSKAVTLE 244
+ T E+ G+ S +GK +LI T S +R++D + +V F G AN + +
Sbjct: 792 EIKET-EFKGIPISYLEIHPNGKRLLIHTKDSTLRIMD-LRILVARKFVGAANYRE-KIH 848
Query: 245 ASFTPDSQFIMIGSEDGKIHVWNGESGIKVAVL-DGKHTGPITCLQFNPKFMTFASACS 302
++ TP F+ GSEDG ++VWN E+G +VA+ D PI + ++P F + C+
Sbjct: 849 STLTPCGTFLFAGSEDGIVYVWNPETGEQVAMYSDLPFKSPIRDISYHP-FENMVAFCA 906
>gi|199559490 Abelson helper integration site 1 isoform a [Homo
sapiens]
Length = 1196
Score = 69.3 bits (168), Expect = 4e-12
Identities = 77/299 (25%), Positives = 128/299 (42%), Gaps = 28/299 (9%)
Query: 26 CFDFSPNGETVIS---SSDDDSIVLYDCQEGKPKRTLYSKKYGVDLIRYTHAANTVVYSS 82
C DFS NG + + S D I+LY+ G+ R L + + ++ + ++ SS
Sbjct: 614 CLDFSHNGRILAAACASRDGYPIILYEIPSGRFMRELCGHLNIIYDLSWSKDDHYILTSS 673
Query: 83 NKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKTIRLWDLRSPNCQ 142
+ I +++ R P S A V + ++G D IR+W +
Sbjct: 674 SDGTARIWKNEINNTNTFRVLPHPSFVYTAKFHPAVRELVVTGCYDSMIRIWKVEMREDS 733
Query: 143 GLM------HLQGKPVCSFDPEGLIFAAG-------VNSEMVKLYDLRSFDKGPFATFKM 189
++ H FD EG +G V + VK+ DL T
Sbjct: 734 AILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNTYVKINDLEH--SVHHWTINK 791
Query: 190 QYDRTCEWTGLKFSN-----DGKLILISTNGSFIRLIDAFKGVVMHTFGGYANSKAVTLE 244
+ T E+ G+ S +GK +LI T S +R++D + +V F G AN + +
Sbjct: 792 EIKET-EFKGIPISYLEIHPNGKRLLIHTKDSTLRIMD-LRILVARKFVGAANYRE-KIH 848
Query: 245 ASFTPDSQFIMIGSEDGKIHVWNGESGIKVAVL-DGKHTGPITCLQFNPKFMTFASACS 302
++ TP F+ GSEDG ++VWN E+G +VA+ D PI + ++P F + C+
Sbjct: 849 STLTPCGTFLFAGSEDGIVYVWNPETGEQVAMYSDLPFKSPIRDISYHP-FENMVAFCA 906
>gi|199559438 Abelson helper integration site 1 isoform a [Homo
sapiens]
Length = 1196
Score = 69.3 bits (168), Expect = 4e-12
Identities = 77/299 (25%), Positives = 128/299 (42%), Gaps = 28/299 (9%)
Query: 26 CFDFSPNGETVIS---SSDDDSIVLYDCQEGKPKRTLYSKKYGVDLIRYTHAANTVVYSS 82
C DFS NG + + S D I+LY+ G+ R L + + ++ + ++ SS
Sbjct: 614 CLDFSHNGRILAAACASRDGYPIILYEIPSGRFMRELCGHLNIIYDLSWSKDDHYILTSS 673
Query: 83 NKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKTIRLWDLRSPNCQ 142
+ I +++ R P S A V + ++G D IR+W +
Sbjct: 674 SDGTARIWKNEINNTNTFRVLPHPSFVYTAKFHPAVRELVVTGCYDSMIRIWKVEMREDS 733
Query: 143 GLM------HLQGKPVCSFDPEGLIFAAG-------VNSEMVKLYDLRSFDKGPFATFKM 189
++ H FD EG +G V + VK+ DL T
Sbjct: 734 AILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNTYVKINDLEH--SVHHWTINK 791
Query: 190 QYDRTCEWTGLKFSN-----DGKLILISTNGSFIRLIDAFKGVVMHTFGGYANSKAVTLE 244
+ T E+ G+ S +GK +LI T S +R++D + +V F G AN + +
Sbjct: 792 EIKET-EFKGIPISYLEIHPNGKRLLIHTKDSTLRIMD-LRILVARKFVGAANYRE-KIH 848
Query: 245 ASFTPDSQFIMIGSEDGKIHVWNGESGIKVAVL-DGKHTGPITCLQFNPKFMTFASACS 302
++ TP F+ GSEDG ++VWN E+G +VA+ D PI + ++P F + C+
Sbjct: 849 STLTPCGTFLFAGSEDGIVYVWNPETGEQVAMYSDLPFKSPIRDISYHP-FENMVAFCA 906
>gi|31542701 Abelson helper integration site 1 isoform a [Homo
sapiens]
Length = 1196
Score = 69.3 bits (168), Expect = 4e-12
Identities = 77/299 (25%), Positives = 128/299 (42%), Gaps = 28/299 (9%)
Query: 26 CFDFSPNGETVIS---SSDDDSIVLYDCQEGKPKRTLYSKKYGVDLIRYTHAANTVVYSS 82
C DFS NG + + S D I+LY+ G+ R L + + ++ + ++ SS
Sbjct: 614 CLDFSHNGRILAAACASRDGYPIILYEIPSGRFMRELCGHLNIIYDLSWSKDDHYILTSS 673
Query: 83 NKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKTIRLWDLRSPNCQ 142
+ I +++ R P S A V + ++G D IR+W +
Sbjct: 674 SDGTARIWKNEINNTNTFRVLPHPSFVYTAKFHPAVRELVVTGCYDSMIRIWKVEMREDS 733
Query: 143 GLM------HLQGKPVCSFDPEGLIFAAG-------VNSEMVKLYDLRSFDKGPFATFKM 189
++ H FD EG +G V + VK+ DL T
Sbjct: 734 AILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNTYVKINDLEH--SVHHWTINK 791
Query: 190 QYDRTCEWTGLKFSN-----DGKLILISTNGSFIRLIDAFKGVVMHTFGGYANSKAVTLE 244
+ T E+ G+ S +GK +LI T S +R++D + +V F G AN + +
Sbjct: 792 EIKET-EFKGIPISYLEIHPNGKRLLIHTKDSTLRIMD-LRILVARKFVGAANYRE-KIH 848
Query: 245 ASFTPDSQFIMIGSEDGKIHVWNGESGIKVAVL-DGKHTGPITCLQFNPKFMTFASACS 302
++ TP F+ GSEDG ++VWN E+G +VA+ D PI + ++P F + C+
Sbjct: 849 STLTPCGTFLFAGSEDGIVYVWNPETGEQVAMYSDLPFKSPIRDISYHP-FENMVAFCA 906
>gi|4557741 platelet-activating factor acetylhydrolase, isoform Ib,
alpha subunit [Homo sapiens]
Length = 410
Score = 68.6 bits (166), Expect = 7e-12
Identities = 65/280 (23%), Positives = 124/280 (44%), Gaps = 23/280 (8%)
Query: 29 FSPNGETVISSSDDDSIVLYDCQEGKPKRTLYSKKYGVDLIRYTHAANTVVYSSNKIDDT 88
F P ++S+S+D +I ++D + G +RTL V I + H+ + +S D T
Sbjct: 116 FHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLL--ASCSADMT 173
Query: 89 IRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKTIRLWDLRSPNCQGLM--H 146
I+ + IR GH V ++++ P D +S S DKTI++W++++ C H
Sbjct: 174 IKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGH 233
Query: 147 LQGKPVCSFDPEGLIFAAGVNSEMVKLY---------DLRSFDKGPFATF---KMQYDRT 194
+ + + +G + A+ N + V+++ +LR + + Y
Sbjct: 234 REWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSI 293
Query: 195 CEWTGLKFSNDGK---LILISTNGSFIRLIDAFKGVVMHTFGGYANSKAVTLEASFTPDS 251
E TG + GK +L + I++ D G+ + T G+ N L F
Sbjct: 294 SEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVL---FHSGG 350
Query: 252 QFIMIGSEDGKIHVWNGESGIKVAVLDGKHTGPITCLQFN 291
+FI+ ++D + VW+ ++ + L+ H +T L F+
Sbjct: 351 KFILSCADDKTLRVWDYKNKRCMKTLNA-HEHFVTSLDFH 389
Score = 53.1 bits (126), Expect = 3e-07
Identities = 61/272 (22%), Positives = 108/272 (39%), Gaps = 28/272 (10%)
Query: 15 KVFRENSDKINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLYSKKYGVDLIRYTHA 74
+ + ++D + F +G+ + S S D +I L+D Q + RT++ + V +
Sbjct: 144 RTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPN 203
Query: 75 ANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKTIRLW 134
+ +V +S D TI+ + ++ F GH + V + + S S D+T+R+W
Sbjct: 204 GDHIVSASR--DKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVW 261
Query: 135 DLRSPNCQGLM--HLQGKPVCSFDPEGLIFAAGVNSEMVKLYDLRSFDKGPF-------A 185
+ + C+ + H S+ PE + SE +S GPF
Sbjct: 262 VVATKECKAELREHEHVVECISWAPESSYSSI---SEATGSETKKSGKPGPFLLSGSRDK 318
Query: 186 TFKMQYDRT--CEWT---------GLKFSNDGKLILISTNGSFIRLIDAFKGVVMHTFGG 234
T KM T C T G+ F + GK IL + +R+ D M T
Sbjct: 319 TIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNA 378
Query: 235 YANSKAVTLEASFTPDSQFIMIGSEDGKIHVW 266
+ + F + +++ GS D + VW
Sbjct: 379 HEH---FVTSLDFHKTAPYVVTGSVDQTVKVW 407
Score = 43.1 bits (100), Expect = 3e-04
Identities = 35/164 (21%), Positives = 64/164 (39%), Gaps = 10/164 (6%)
Query: 105 GHSKRVVALSMSPVDDTFISGSLDKTIRLWDLRSPNCQGLM--HLQGKPVCSFDPEGLIF 162
GH V + PV +S S D TI++WD + + + + H SFD G +
Sbjct: 106 GHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLL 165
Query: 163 AAGVNSEMVKLYDLRSFDKGPFATFKMQYDRTCEWTGLKFSNDGKLILISTNGSFIRLID 222
A+ +KL+D + F+ + + + + +G I+ ++ I++ +
Sbjct: 166 ASCSADMTIKLWDFQGFE-----CIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWE 220
Query: 223 AFKGVVMHTFGGYANSKAVTLEASFTPDSQFIMIGSEDGKIHVW 266
G + TF G+ + D I S D + VW
Sbjct: 221 VQTGYCVKTFTGHREWVRMVRP---NQDGTLIASCSNDQTVRVW 261
Score = 36.6 bits (83), Expect = 0.030
Identities = 22/105 (20%), Positives = 47/105 (44%), Gaps = 2/105 (1%)
Query: 33 GETVISSSDDDSIVLYDCQEGKPKRTLYSKKYGVDLIRYTHAANTVVYSSNKIDDTIRYL 92
G ++S S D +I ++D G TL V + + ++ ++ D T+R
Sbjct: 308 GPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCAD--DKTLRVW 365
Query: 93 SLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKTIRLWDLR 137
+ + ++ H V +L ++GS+D+T+++W+ R
Sbjct: 366 DYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR 410
>gi|5729852 guanine nucleotide-binding protein, beta-5 subunit
isoform a [Homo sapiens]
Length = 353
Score = 67.0 bits (162), Expect = 2e-11
Identities = 59/249 (23%), Positives = 104/249 (41%), Gaps = 20/249 (8%)
Query: 29 FSPNGETVISSSDDDSIVLYDCQEGKPKRTLYSKKYGVDLIRYTHAANTVVYSSNKI--- 85
++P+G + D+ +Y K + KK + +T+ + ++++ +
Sbjct: 113 YAPSGCAIACGGLDNKCSVYPLTFDKNENMAAKKK---SVAMHTNYLSACSFTNSDMQIL 169
Query: 86 ----DDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVD--DTFISGSLDKTIRLWDLRSP 139
D T + + ++ F GH V+ L ++P + +TF+SG DK +WD+RS
Sbjct: 170 TASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSG 229
Query: 140 NCQGLMHLQGKPVCS--FDPEGLIFAAGVNSEMVKLYDLRSFDKGPFATFKMQYDRTCEW 197
C + S + P G FA+G + +LYDLR+ + +
Sbjct: 230 QCVQAFETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADRE---VAIYSKESIIFGA 286
Query: 198 TGLKFSNDGKLILISTNGSFIRLIDAFKGVVMHTFGGYANSKAVTLEASFTPDSQFIMIG 257
+ + FS G+L+ N I + D KG + G+ N + TL S PD G
Sbjct: 287 SSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFGHEN-RVSTLRVS--PDGTAFCSG 343
Query: 258 SEDGKIHVW 266
S D + VW
Sbjct: 344 SWDHTLRVW 352
Score = 56.2 bits (134), Expect = 4e-08
Identities = 37/130 (28%), Positives = 61/130 (46%), Gaps = 6/130 (4%)
Query: 8 LRSFRVAKVFRENSDKINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLYSKK---Y 64
+RS + + F + IN + P+G+ S SDD + LYD + + + +YSK+ +
Sbjct: 226 MRSGQCVQAFETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADR-EVAIYSKESIIF 284
Query: 65 GVDLIRYTHAANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFIS 124
G + ++ + + N D TI + + GH RV L +SP F S
Sbjct: 285 GASSVDFSLSGRLLFAGYN--DYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCS 342
Query: 125 GSLDKTIRLW 134
GS D T+R+W
Sbjct: 343 GSWDHTLRVW 352
Score = 48.1 bits (113), Expect = 1e-05
Identities = 50/221 (22%), Positives = 88/221 (39%), Gaps = 7/221 (3%)
Query: 83 NKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKTIRLWDLRSPNCQ 142
+++ + + L K R GH +V+ + +S S D + +WD + N +
Sbjct: 39 HQVAERVEALGQFVMKTRRTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKE 98
Query: 143 GLMHLQGKPV--CSFDPEGLIFAAGVNSEMVKLYDLRSFDKGP--FATFKMQYDRTCEWT 198
+ + V C++ P G A G +Y L +FDK A K T +
Sbjct: 99 HAVTMPCTWVMACAYAPSGCAIACGGLDNKCSVYPL-TFDKNENMAAKKKSVAMHTNYLS 157
Query: 199 GLKFSNDGKLILISTNGSFIRLIDAFKGVVMHTFGGYANSKAVTLEASFTPDSQFIMIGS 258
F+N IL ++ L D G ++ +F G+ + + L+ + + + G
Sbjct: 158 ACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGH-GADVLCLDLAPSETGNTFVSGG 216
Query: 259 EDGKIHVWNGESGIKVAVLDGKHTGPITCLQFNPKFMTFAS 299
D K VW+ SG V + H I +++ P FAS
Sbjct: 217 CDKKAMVWDMRSGQCVQAFE-THESDINSVRYYPSGDAFAS 256
>gi|20336270 guanine nucleotide-binding protein, beta-5 subunit
isoform b [Homo sapiens]
Length = 395
Score = 67.0 bits (162), Expect = 2e-11
Identities = 59/249 (23%), Positives = 104/249 (41%), Gaps = 20/249 (8%)
Query: 29 FSPNGETVISSSDDDSIVLYDCQEGKPKRTLYSKKYGVDLIRYTHAANTVVYSSNKI--- 85
++P+G + D+ +Y K + KK + +T+ + ++++ +
Sbjct: 155 YAPSGCAIACGGLDNKCSVYPLTFDKNENMAAKKK---SVAMHTNYLSACSFTNSDMQIL 211
Query: 86 ----DDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVD--DTFISGSLDKTIRLWDLRSP 139
D T + + ++ F GH V+ L ++P + +TF+SG DK +WD+RS
Sbjct: 212 TASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSG 271
Query: 140 NCQGLMHLQGKPVCS--FDPEGLIFAAGVNSEMVKLYDLRSFDKGPFATFKMQYDRTCEW 197
C + S + P G FA+G + +LYDLR+ + +
Sbjct: 272 QCVQAFETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADRE---VAIYSKESIIFGA 328
Query: 198 TGLKFSNDGKLILISTNGSFIRLIDAFKGVVMHTFGGYANSKAVTLEASFTPDSQFIMIG 257
+ + FS G+L+ N I + D KG + G+ N + TL S PD G
Sbjct: 329 SSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFGHEN-RVSTLRVS--PDGTAFCSG 385
Query: 258 SEDGKIHVW 266
S D + VW
Sbjct: 386 SWDHTLRVW 394
Score = 56.2 bits (134), Expect = 4e-08
Identities = 37/130 (28%), Positives = 61/130 (46%), Gaps = 6/130 (4%)
Query: 8 LRSFRVAKVFRENSDKINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLYSKK---Y 64
+RS + + F + IN + P+G+ S SDD + LYD + + + +YSK+ +
Sbjct: 268 MRSGQCVQAFETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADR-EVAIYSKESIIF 326
Query: 65 GVDLIRYTHAANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFIS 124
G + ++ + + N D TI + + GH RV L +SP F S
Sbjct: 327 GASSVDFSLSGRLLFAGYN--DYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCS 384
Query: 125 GSLDKTIRLW 134
GS D T+R+W
Sbjct: 385 GSWDHTLRVW 394
Score = 48.1 bits (113), Expect = 1e-05
Identities = 50/221 (22%), Positives = 88/221 (39%), Gaps = 7/221 (3%)
Query: 83 NKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKTIRLWDLRSPNCQ 142
+++ + + L K R GH +V+ + +S S D + +WD + N +
Sbjct: 81 HQVAERVEALGQFVMKTRRTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKE 140
Query: 143 GLMHLQGKPV--CSFDPEGLIFAAGVNSEMVKLYDLRSFDKGP--FATFKMQYDRTCEWT 198
+ + V C++ P G A G +Y L +FDK A K T +
Sbjct: 141 HAVTMPCTWVMACAYAPSGCAIACGGLDNKCSVYPL-TFDKNENMAAKKKSVAMHTNYLS 199
Query: 199 GLKFSNDGKLILISTNGSFIRLIDAFKGVVMHTFGGYANSKAVTLEASFTPDSQFIMIGS 258
F+N IL ++ L D G ++ +F G+ + + L+ + + + G
Sbjct: 200 ACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGH-GADVLCLDLAPSETGNTFVSGG 258
Query: 259 EDGKIHVWNGESGIKVAVLDGKHTGPITCLQFNPKFMTFAS 299
D K VW+ SG V + H I +++ P FAS
Sbjct: 259 CDKKAMVWDMRSGQCVQAFE-THESDINSVRYYPSGDAFAS 298
>gi|21071067 TBP-associated factor 5 [Homo sapiens]
Length = 800
Score = 67.0 bits (162), Expect = 2e-11
Identities = 62/263 (23%), Positives = 109/263 (41%), Gaps = 18/263 (6%)
Query: 33 GETVISSSDDDSIVLYDCQEGKPKRTLYSKKYGVDLIRYTHAANTVVYSSNKIDDTI-RY 91
G T + +DD S++ + + + K +R A+ + + DD + R
Sbjct: 472 GLTAVDVTDDSSLIAGGFADSTVRVWSVTPKK----LRSVKQASDLSLIDKESDDVLERI 527
Query: 92 LSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKTIRLWDLRSPNCQGLMHLQGKP 151
+ ++ GHS V S SP + +S S D T+RLW L++ C P
Sbjct: 528 MDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYP 587
Query: 152 V--CSFDPEGLIFAAGVNSEMVKLYDLRSFDKGPFATFKMQY-DRTCEWTGLKFSNDGKL 208
V F P G F +G + + +L+ + P F D C +F +
Sbjct: 588 VWDTQFSPYGYYFVSGGHDRVARLWATDHYQ--PLRIFAGHLADVNCT----RFHPNSNY 641
Query: 209 ILISTNGSFIRLIDAFKGVVMHTFGGYANSKAVTLEASFTPDSQFIMIGSEDGKIHVWNG 268
+ + +RL D G + F G+ K +F+P+ +F+ G+ DG++ +W+
Sbjct: 642 VATGSADRTVRLWDVLNGNCVRIFTGH---KGPIHSLTFSPNGRFLATGATDGRVLLWDI 698
Query: 269 ESGIKVAVLDGKHTGPITCLQFN 291
G+ V L G HT + L+F+
Sbjct: 699 GHGLMVGELKG-HTDTVCSLRFS 720
Score = 62.8 bits (151), Expect = 4e-10
Identities = 55/213 (25%), Positives = 89/213 (41%), Gaps = 9/213 (4%)
Query: 15 KVFRENSDKINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLYSKKYGVDLIRYTHA 74
K+ +S + FSP+ ++SSS+D ++ L+ Q Y V +++
Sbjct: 537 KILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPY 596
Query: 75 ANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKTIRLW 134
V + D R + + +R F GH V P + +GS D+T+RLW
Sbjct: 597 GYYFVSGGH--DRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLW 654
Query: 135 DLRSPNCQGLMHLQGKPVCS--FDPEGLIFAAGVNSEMVKLYDLRSFDKGPFATFKMQYD 192
D+ + NC + P+ S F P G A G V L+D+ K D
Sbjct: 655 DVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIG--HGLMVGELKGHTD 712
Query: 193 RTCEWTGLKFSNDGKLILISTNGSFIRLIDAFK 225
C L+FS DG+++ + + +RL DA K
Sbjct: 713 TVC---SLRFSRDGEILASGSMDNTVRLWDAIK 742
Score = 50.4 bits (119), Expect = 2e-06
Identities = 31/125 (24%), Positives = 54/125 (43%), Gaps = 2/125 (1%)
Query: 11 FRVAKVFRENSDKINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLYSKKYGVDLIR 70
++ ++F + +NC F PN V + S D ++ L+D G R K + +
Sbjct: 617 YQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSL- 675
Query: 71 YTHAANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKT 130
T + N ++ D + + + GH+ V +L S + SGS+D T
Sbjct: 676 -TFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNT 734
Query: 131 IRLWD 135
+RLWD
Sbjct: 735 VRLWD 739
Score = 35.4 bits (80), Expect = 0.066
Identities = 18/55 (32%), Positives = 30/55 (54%), Gaps = 1/55 (1%)
Query: 245 ASFTPDSQFIMIGSEDGKIHVWNGESGIKVAVLDGKHTGPITCLQFNPKFMTFAS 299
ASF+PD +++ SEDG + +W+ ++ + G H P+ QF+P F S
Sbjct: 549 ASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKG-HNYPVWDTQFSPYGYYFVS 602
>gi|153791298 mitogen-activated protein kinase organizer 1 [Homo
sapiens]
Length = 315
Score = 67.0 bits (162), Expect = 2e-11
Identities = 66/267 (24%), Positives = 119/267 (44%), Gaps = 15/267 (5%)
Query: 29 FSPNGETVISSSDDDSIVLYDCQEGKPKRTLYSKKYGVDLIRYTHAANTVVYSSNKIDDT 88
F+ +G ++ D ++ L++ G RT YS +G +++ + + S D
Sbjct: 33 FNVDGNYCLTCGSDKTLKLWNPLRGTLLRT-YSG-HGYEVLDAAGSFDNSSLCSGGGDKA 90
Query: 89 IRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKTIRLWDLRSPNCQGLMHLQ 148
+ + + +R F GH+ +V + + +SGS+D +IR WD RS + + L
Sbjct: 91 VVLWDVASGQVVRKFRGHAGKVNTVQFNEEATVILSGSIDSSIRCWDCRSRRPEPVQTLD 150
Query: 149 --GKPVCSFDPEGLIFAAGVNSEMVKLYDLRSFDKGPFATFKMQYDRTCEWTGLKFSNDG 206
V S AG V+ YDLR G + + TC FS DG
Sbjct: 151 EARDGVSSVKVSDHEILAGSVDGRVRRYDLR---MGQLFSDYVGSPITCTC----FSRDG 203
Query: 207 KLILISTNGSFIRLIDAFKGVVMHTFGGYANSKAVTLEASFTPDSQFIMIGSEDGKIHVW 266
+ L+S+ S +RL+D G ++ + G+ N + L+ + ++ SEDGK+ W
Sbjct: 204 QCTLVSSLDSTLRLLDKDTGELLGEYKGHKNQE-YKLDCCLSERDTHVVSCSEDGKVFFW 262
Query: 267 N-GESGIKVAVLDGKHTGPITCLQFNP 292
+ E + +A+ G +G + L ++P
Sbjct: 263 DLVEGALALALPVG--SGVVQSLAYHP 287
Score = 40.8 bits (94), Expect = 0.002
Identities = 31/128 (24%), Positives = 56/128 (43%), Gaps = 8/128 (6%)
Query: 10 SFRVAKVFRENSDKINCFDFSPNGETVISSSDDDSIVLYDCQEGKPK--RTLYSKKYGVD 67
S +V + FR ++ K+N F+ ++S S D SI +DC+ +P+ +TL + GV
Sbjct: 98 SGQVVRKFRGHAGKVNTVQFNEEATVILSGSIDSSIRCWDCRSRRPEPVQTLDEARDGVS 157
Query: 68 LIRYTHAANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSL 127
++ + + +D +R L + + G + S + SL
Sbjct: 158 SVKVSDHE----ILAGSVDGRVRRYDLRMGQLFSDYVG--SPITCTCFSRDGQCTLVSSL 211
Query: 128 DKTIRLWD 135
D T+RL D
Sbjct: 212 DSTLRLLD 219
>gi|14150114 mitogen-activated protein kinase organizer 1 [Homo
sapiens]
Length = 315
Score = 67.0 bits (162), Expect = 2e-11
Identities = 66/267 (24%), Positives = 119/267 (44%), Gaps = 15/267 (5%)
Query: 29 FSPNGETVISSSDDDSIVLYDCQEGKPKRTLYSKKYGVDLIRYTHAANTVVYSSNKIDDT 88
F+ +G ++ D ++ L++ G RT YS +G +++ + + S D
Sbjct: 33 FNVDGNYCLTCGSDKTLKLWNPLRGTLLRT-YSG-HGYEVLDAAGSFDNSSLCSGGGDKA 90
Query: 89 IRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKTIRLWDLRSPNCQGLMHLQ 148
+ + + +R F GH+ +V + + +SGS+D +IR WD RS + + L
Sbjct: 91 VVLWDVASGQVVRKFRGHAGKVNTVQFNEEATVILSGSIDSSIRCWDCRSRRPEPVQTLD 150
Query: 149 --GKPVCSFDPEGLIFAAGVNSEMVKLYDLRSFDKGPFATFKMQYDRTCEWTGLKFSNDG 206
V S AG V+ YDLR G + + TC FS DG
Sbjct: 151 EARDGVSSVKVSDHEILAGSVDGRVRRYDLR---MGQLFSDYVGSPITCTC----FSRDG 203
Query: 207 KLILISTNGSFIRLIDAFKGVVMHTFGGYANSKAVTLEASFTPDSQFIMIGSEDGKIHVW 266
+ L+S+ S +RL+D G ++ + G+ N + L+ + ++ SEDGK+ W
Sbjct: 204 QCTLVSSLDSTLRLLDKDTGELLGEYKGHKNQE-YKLDCCLSERDTHVVSCSEDGKVFFW 262
Query: 267 N-GESGIKVAVLDGKHTGPITCLQFNP 292
+ E + +A+ G +G + L ++P
Sbjct: 263 DLVEGALALALPVG--SGVVQSLAYHP 287
Score = 40.8 bits (94), Expect = 0.002
Identities = 31/128 (24%), Positives = 56/128 (43%), Gaps = 8/128 (6%)
Query: 10 SFRVAKVFRENSDKINCFDFSPNGETVISSSDDDSIVLYDCQEGKPK--RTLYSKKYGVD 67
S +V + FR ++ K+N F+ ++S S D SI +DC+ +P+ +TL + GV
Sbjct: 98 SGQVVRKFRGHAGKVNTVQFNEEATVILSGSIDSSIRCWDCRSRRPEPVQTLDEARDGVS 157
Query: 68 LIRYTHAANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSL 127
++ + + +D +R L + + G + S + SL
Sbjct: 158 SVKVSDHE----ILAGSVDGRVRRYDLRMGQLFSDYVG--SPITCTCFSRDGQCTLVSSL 211
Query: 128 DKTIRLWD 135
D T+RL D
Sbjct: 212 DSTLRLLD 219
>gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo
sapiens]
Length = 514
Score = 66.6 bits (161), Expect = 3e-11
Identities = 53/263 (20%), Positives = 108/263 (41%), Gaps = 44/263 (16%)
Query: 13 VAKVFRENSDKINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTL-YSKKYGVDLIRY 71
+A ++ I ++ G ++S+ D + +++D G+ K+ + +D+
Sbjct: 258 LASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQ 317
Query: 72 THAANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKTI 131
++ NT ++S D I L ++ I+ F GH+ V A+ P + S S D T+
Sbjct: 318 SN--NT--FASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTL 373
Query: 132 RLWDLRSPNCQGLMHLQGKPVCSFDPEGLIFAAGVNSEMVKLYDLRSFDKGPFATFKMQY 191
++W ++ NC + K ++Y ++ GP
Sbjct: 374 KIWSMKQDNCVHDLQAHNK---------------------EIYTIKWSPTGP-------- 404
Query: 192 DRTCEWTGLKFSNDGKLILISTNGSFIRLIDAFKGVVMHTFGGYANSKAVTLEASFTPDS 251
G N ++ ++ S +RL D +G+ +HT + +F+PD
Sbjct: 405 -------GTNNPNANLMLASASFDSTVRLWDVDRGICIHTL---TKHQEPVYSVAFSPDG 454
Query: 252 QFIMIGSEDGKIHVWNGESGIKV 274
+++ GS D +H+WN ++G V
Sbjct: 455 RYLASGSFDKCVHIWNTQTGALV 477
Score = 46.2 bits (108), Expect = 4e-05
Identities = 29/134 (21%), Positives = 62/134 (46%), Gaps = 7/134 (5%)
Query: 12 RVAKVFRENSDKINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLYSKKYGVDLIRY 71
R K F+ +++++N + P G + S SDD ++ ++ ++ L + + I++
Sbjct: 340 RPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKW 399
Query: 72 ------THAAN-TVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFIS 124
T+ N ++ +S D T+R + I H + V +++ SP S
Sbjct: 400 SPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLAS 459
Query: 125 GSLDKTIRLWDLRS 138
GS DK + +W+ ++
Sbjct: 460 GSFDKCVHIWNTQT 473
Score = 40.4 bits (93), Expect = 0.002
Identities = 51/216 (23%), Positives = 79/216 (36%), Gaps = 27/216 (12%)
Query: 105 GHSKRVVALSMSPVDDTFISGSLDKTIRLWDLRSPNCQGLMHL--------------QGK 150
GH V + +PV D SGS D T R+W+L + G L K
Sbjct: 167 GHESEVFICAWNPVSDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPSNK 226
Query: 151 PVCSFD--PEGLIFAAGVNSEMVKLYDLRSFDKGPFATFKMQYDRTCEWTGLKFSNDGKL 208
V S D EG + A G +++ G A+ Q+ LK++ G
Sbjct: 227 DVTSLDWNSEGTLLATGSYDGFARIWT----KDGNLASTLGQHKGPI--FALKWNKKGNF 280
Query: 209 ILISTNGSFIRLIDAFKGVVMHTFGGYANSKAVTLEASFTPDSQFIMIGSEDGKIHVWNG 268
IL + + DA G F ++ A L+ + ++ F S D IHV
Sbjct: 281 ILSAGVDKTTIIWDAHTGEAKQQFPFHS---APALDVDWQSNNTFASC-STDMCIHVCKL 336
Query: 269 ESGIKVAVLDGKHTGPITCLQFNPKFMTFASACSNM 304
+ G HT + ++++P AS +M
Sbjct: 337 GQDRPIKTFQG-HTNEVNAIKWDPTGNLLASCSDDM 371
>gi|13376840 WD repeat domain 61 [Homo sapiens]
Length = 305
Score = 65.9 bits (159), Expect = 5e-11
Identities = 57/234 (24%), Positives = 99/234 (42%), Gaps = 17/234 (7%)
Query: 76 NTVVYSSNKIDDTIRYLSLHDNKYIRYFP--GHSKRVVALSMSPVDDTFISGSLDKTIRL 133
N+ + +DD ++ D + + GH VV++ +S S SLD IRL
Sbjct: 31 NSETVVTGSLDDLVKVWKWRDERLDLQWSLEGHQLGVVSVDISHTLPIAASSSLDAHIRL 90
Query: 134 WDLRSPNCQGLMHLQGKPV----CSFDPEGLIFAAGVNSEMVKLYDLRSFDKGPFATFKM 189
WDL N + + + PV +F P+ A G + V ++ + S K +
Sbjct: 91 WDLE--NGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRG 148
Query: 190 QYDRTCEWTGLKFSNDGKLILISTNGSFIRLIDAFKGVVMHTFGGYANSKAVTLEASFTP 249
++ + +S DGK + I + D G ++HT G+A +F+P
Sbjct: 149 KF-----ILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHA---MPIRSLTFSP 200
Query: 250 DSQFIMIGSEDGKIHVWNGESGIKVAVLDGKHTGPITCLQFNPKFMTFASACSN 303
DSQ ++ S+DG I +++ + L G H + + F P F S+ S+
Sbjct: 201 DSQLLVTASDDGYIKIYDVQHANLAGTLSG-HASWVLNVAFCPDDTHFVSSSSD 253
Score = 59.3 bits (142), Expect = 4e-09
Identities = 52/243 (21%), Positives = 108/243 (44%), Gaps = 20/243 (8%)
Query: 32 NGETVISSSDDDSIVLYDCQEGKP--KRTLYSKKYGVDLIRYTHAANTVVYSSNKIDDTI 89
N ETV++ S DD + ++ ++ + + +L + GV + +H + +S+ +D I
Sbjct: 31 NSETVVTGSLDDLVKVWKWRDERLDLQWSLEGHQLGVVSVDISHTLP--IAASSSLDAHI 88
Query: 90 RYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKTIRLWDLRSPNCQGLMHLQG 149
R L + K I+ L+ SP +G+ + ++ + S + + +G
Sbjct: 89 RLWDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRG 148
Query: 150 KPVCS--FDPEGLIFAAGVNSEMVKLYDLRSFDKGPFATFKMQYD---RTCEWTGLKFSN 204
K + S + P+G A+G ++ ++D+ AT K+ + L FS
Sbjct: 149 KFILSIAYSPDGKYLASGAIDGIINIFDI--------ATGKLLHTLEGHAMPIRSLTFSP 200
Query: 205 DGKLILISTNGSFIRLIDAFKGVVMHTFGGYANSKAVTLEASFTPDSQFIMIGSEDGKIH 264
D +L++ +++ +I++ D + T G+A+ L +F PD + S D +
Sbjct: 201 DSQLLVTASDDGYIKIYDVQHANLAGTLSGHASW---VLNVAFCPDDTHFVSSSSDKSVK 257
Query: 265 VWN 267
VW+
Sbjct: 258 VWD 260
Score = 51.2 bits (121), Expect = 1e-06
Identities = 38/196 (19%), Positives = 88/196 (44%), Gaps = 9/196 (4%)
Query: 29 FSPNGETVISSSDDDSIVLYDCQEGKPKRTLYSKKYGVDLIRYTHAANTVVYSSNKIDDT 88
FSP+ + + + + + ++ + GK + +L ++ G ++ ++ + +S ID
Sbjct: 114 FSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTR--GKFILSIAYSPDGKYLASGAIDGI 171
Query: 89 IRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKTIRLWDLRSPNCQGLM--H 146
I + K + GH+ + +L+ SP ++ S D I+++D++ N G + H
Sbjct: 172 INIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGH 231
Query: 147 LQGKPVCSFDPEGLIFAAGVNSEMVKLYDLRSFDKGPFATFKMQYDRTCEWTGLKFSNDG 206
+F P+ F + + + VK++D+ G +D + G+K++ +G
Sbjct: 232 ASWVLNVAFCPDDTHFVSSSSDKSVKVWDV-----GTRTCVHTFFDHQDQVWGVKYNGNG 286
Query: 207 KLILISTNGSFIRLID 222
I+ + I + D
Sbjct: 287 SKIVSVGDDQEIHIYD 302
Score = 38.5 bits (88), Expect = 0.008
Identities = 26/118 (22%), Positives = 44/118 (37%), Gaps = 44/118 (37%)
Query: 24 INCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLYSKKYGVDLIRYTHAANTVVYSSN 83
I FSP+ + ++++SDD I +YD Q TL
Sbjct: 193 IRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTL------------------------ 228
Query: 84 KIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKTIRLWDLRSPNC 141
GH+ V+ ++ P D F+S S DK++++WD+ + C
Sbjct: 229 --------------------SGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGTRTC 266
Score = 29.6 bits (65), Expect = 3.6
Identities = 11/34 (32%), Positives = 20/34 (58%)
Query: 17 FRENSDKINCFDFSPNGETVISSSDDDSIVLYDC 50
F ++ D++ ++ NG ++S DD I +YDC
Sbjct: 270 FFDHQDQVWGVKYNGNGSKIVSVGDDQEIHIYDC 303
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.418
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,553,774
Number of Sequences: 37866
Number of extensions: 491995
Number of successful extensions: 2757
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 173
Number of HSP's successfully gapped in prelim test: 89
Number of HSP's that attempted gapping in prelim test: 1168
Number of HSP's gapped (non-prelim): 1042
length of query: 313
length of database: 18,247,518
effective HSP length: 102
effective length of query: 211
effective length of database: 14,385,186
effective search space: 3035274246
effective search space used: 3035274246
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.