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Search of human proteins with 14670266
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo
sapiens]
(500 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo s... 1039 0.0
gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo sa... 970 0.0
gi|21630277 tripartite motif-containing 11 [Homo sapiens] 291 9e-79
gi|112421127 tripartite motif-containing 58 [Homo sapiens] 290 2e-78
gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens] 278 8e-75
gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens] 278 8e-75
gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens] 253 4e-67
gi|15208660 tripartite motif protein 21 [Homo sapiens] 248 1e-65
gi|68160935 tripartite motif-containing 17 isoform 2 [Homo sapiens] 247 2e-65
gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens] 243 3e-64
gi|5730009 ret finger protein [Homo sapiens] 241 9e-64
gi|157743261 tripartite motif-containing 75 [Homo sapiens] 241 1e-63
gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens] 237 2e-62
gi|37622899 ring finger protein 137 [Homo sapiens] 232 7e-61
gi|5454014 tripartite motif-containing 38 [Homo sapiens] 220 3e-57
gi|22749269 ring finger protein 129 [Homo sapiens] 209 5e-54
gi|198442878 tripartite motif-containing 17 isoform 3 [Homo sapi... 206 4e-53
gi|20270353 tripartite motif-containing 43 [Homo sapiens] 203 3e-52
gi|31542779 tripartite motif family-like 1 [Homo sapiens] 202 4e-52
gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens] 201 2e-51
gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens] 201 2e-51
gi|157426898 tripartite motif-containing 10 isoform 1 [Homo sapi... 197 2e-50
gi|88953346 PREDICTED: Tripartite motif-containing protein 43-li... 196 4e-50
gi|210147600 tripartite motif-containing 64 [Homo sapiens] 184 1e-46
gi|169202375 PREDICTED: tripartite motif-containing protein 64B-... 184 1e-46
gi|14719418 tripartite motif protein TRIM5 isoform alpha [Homo s... 184 2e-46
gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens] 182 5e-46
gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens] 182 5e-46
gi|51477690 tripartite motif-containing 6 and tripartite motif-c... 182 5e-46
gi|239755488 PREDICTED: similar to ring finger protein 18 isofor... 176 3e-44
>gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo
sapiens]
Length = 500
Score = 1039 bits (2686), Expect = 0.0
Identities = 500/500 (100%), Positives = 500/500 (100%)
Query: 1 MEAEDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAA 60
MEAEDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAA
Sbjct: 1 MEAEDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAA 60
Query: 61 LRPNWALARLTEKTQRRRLGPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHAM 120
LRPNWALARLTEKTQRRRLGPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHAM
Sbjct: 61 LRPNWALARLTEKTQRRRLGPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHAM 120
Query: 121 APIDEAFESYRTGNFDIHVDEWKRRLIRLLLYHSKQEEKLLKSQRNLVAKMKKVMHLQDV 180
APIDEAFESYRTGNFDIHVDEWKRRLIRLLLYHSKQEEKLLKSQRNLVAKMKKVMHLQDV
Sbjct: 121 APIDEAFESYRTGNFDIHVDEWKRRLIRLLLYHSKQEEKLLKSQRNLVAKMKKVMHLQDV 180
Query: 181 EVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLN 240
EVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLN
Sbjct: 181 EVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLN 240
Query: 241 QTIASLKKLILEVGEKSQAPTLELLQNPKEVLTRSEIQDVNYSLEAVKVKTVCQIPLMKE 300
QTIASLKKLILEVGEKSQAPTLELLQNPKEVLTRSEIQDVNYSLEAVKVKTVCQIPLMKE
Sbjct: 241 QTIASLKKLILEVGEKSQAPTLELLQNPKEVLTRSEIQDVNYSLEAVKVKTVCQIPLMKE 300
Query: 301 MLKRFQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFV 360
MLKRFQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFV
Sbjct: 301 MLKRFQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFV 360
Query: 361 ERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIY 420
ERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIY
Sbjct: 361 ERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIY 420
Query: 421 WSAAGYWPLIGFPGTPTQQEPALHRVGVYLDRGTGNVSFYSAVDGVHLHTFSCSSVSRLR 480
WSAAGYWPLIGFPGTPTQQEPALHRVGVYLDRGTGNVSFYSAVDGVHLHTFSCSSVSRLR
Sbjct: 421 WSAAGYWPLIGFPGTPTQQEPALHRVGVYLDRGTGNVSFYSAVDGVHLHTFSCSSVSRLR 480
Query: 481 PFFWLSPLASLVIPPVTDRK 500
PFFWLSPLASLVIPPVTDRK
Sbjct: 481 PFFWLSPLASLVIPPVTDRK 500
>gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo
sapiens]
Length = 474
Score = 970 bits (2508), Expect = 0.0
Identities = 474/500 (94%), Positives = 474/500 (94%), Gaps = 26/500 (5%)
Query: 1 MEAEDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAA 60
MEAEDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAA
Sbjct: 1 MEAEDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAA 60
Query: 61 LRPNWALARLTEKTQRRRLGPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHAM 120
LRPNWALARLTEKTQRRRLGPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHAM
Sbjct: 61 LRPNWALARLTEKTQRRRLGPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHAM 120
Query: 121 APIDEAFESYRTGNFDIHVDEWKRRLIRLLLYHSKQEEKLLKSQRNLVAKMKKVMHLQDV 180
APIDEAFESYR EKLLKSQRNLVAKMKKVMHLQDV
Sbjct: 121 APIDEAFESYR--------------------------EKLLKSQRNLVAKMKKVMHLQDV 154
Query: 181 EVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLN 240
EVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLN
Sbjct: 155 EVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLN 214
Query: 241 QTIASLKKLILEVGEKSQAPTLELLQNPKEVLTRSEIQDVNYSLEAVKVKTVCQIPLMKE 300
QTIASLKKLILEVGEKSQAPTLELLQNPKEVLTRSEIQDVNYSLEAVKVKTVCQIPLMKE
Sbjct: 215 QTIASLKKLILEVGEKSQAPTLELLQNPKEVLTRSEIQDVNYSLEAVKVKTVCQIPLMKE 274
Query: 301 MLKRFQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFV 360
MLKRFQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFV
Sbjct: 275 MLKRFQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFV 334
Query: 361 ERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIY 420
ERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIY
Sbjct: 335 ERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIY 394
Query: 421 WSAAGYWPLIGFPGTPTQQEPALHRVGVYLDRGTGNVSFYSAVDGVHLHTFSCSSVSRLR 480
WSAAGYWPLIGFPGTPTQQEPALHRVGVYLDRGTGNVSFYSAVDGVHLHTFSCSSVSRLR
Sbjct: 395 WSAAGYWPLIGFPGTPTQQEPALHRVGVYLDRGTGNVSFYSAVDGVHLHTFSCSSVSRLR 454
Query: 481 PFFWLSPLASLVIPPVTDRK 500
PFFWLSPLASLVIPPVTDRK
Sbjct: 455 PFFWLSPLASLVIPPVTDRK 474
>gi|21630277 tripartite motif-containing 11 [Homo sapiens]
Length = 468
Score = 291 bits (745), Expect = 9e-79
Identities = 185/495 (37%), Positives = 253/495 (51%), Gaps = 57/495 (11%)
Query: 5 DIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAALRPN 64
++QEE TC ICLDYF DPV +CGHNFCR C+ R W GP+ CPECR S LRPN
Sbjct: 9 NLQEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQPEGPYACPECRELSPQRNLRPN 68
Query: 65 WALARLTEKTQR-RRLGPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHAMAPI 123
LA++ E +R PVP G+C H EPL FC D+ R +C C S EH H + P+
Sbjct: 69 RPLAKMAEMARRLHPPSPVPQGVCPAHREPLAAFCGDELRLLCAACERSGEHWAHRVRPL 128
Query: 124 DEAFESYRTGNFDIHVDEWKRRLIRLLLYHSKQEEKLLKSQRNLVAKMKKVMHLQDVEVK 183
+A E + KL KS +L +M+ + Q +
Sbjct: 129 QDAAEDLKA--------------------------KLEKSLEHLRKQMQDALLFQAQADE 162
Query: 184 NATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTI 243
W+ ++SQR + EF +L L EEE LQRL +EE E +L E L Q
Sbjct: 163 TCVLWQKMVESQRQNVLGEFERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQS 222
Query: 244 ASLKKLILEVGEKSQAPTLELLQNPKEVLTRSEIQDVNY---SLEAVKVKTVCQIPLMKE 300
A L +LI E+ + Q P L LLQ+ K+ L R +QDV + ++++TVC++P + E
Sbjct: 223 AHLAELIAELEGRCQLPALGLLQDIKDALRR--VQDVKLQPPEVVPMELRTVCRVPGLVE 280
Query: 301 MLKRFQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFV 360
L+RF+ V L DTA+P+L+ S++ R V+ + P +P
Sbjct: 281 TLRRFRGDVTLDPDTANPELILSEDRRSVQRGDLRQALP------------DSP------ 322
Query: 361 ERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIY 420
ERF PCVLG+ FTSG+HYWEVE D A+GVCRE+V ++ ++S G W +
Sbjct: 323 ERFDPGPCVLGQERFTSGRHYWEVEVGDRTSWALGVCRENV-NRKEKGELSAGNGFWILV 381
Query: 421 WSAAGYWPLIGFPGTPTQQEPALHRVGVYLDRGTGNVSFYSAVDGVHLHTFSCSSVS-RL 479
+ Y+ P + P RVG++LD G++SFYSA DG L F S L
Sbjct: 382 F-LGSYYNSSERALAPLRDPP--RRVGIFLDYEAGHLSFYSATDGSLLFIFPEIPFSGTL 438
Query: 480 RPFFWLSPLASLVIP 494
RP F SPL+S P
Sbjct: 439 RPLF--SPLSSSPTP 451
>gi|112421127 tripartite motif-containing 58 [Homo sapiens]
Length = 486
Score = 290 bits (743), Expect = 2e-78
Identities = 171/500 (34%), Positives = 258/500 (51%), Gaps = 51/500 (10%)
Query: 4 EDIQEELTCPICLDYFQDPVSIECGHNFCRGCL----HRNWAPGGGPFPCPECRHPSAPA 59
E ++E+ CP+CLD+ Q+PVS++CGH+FC C+ ++ GG + CP+CR P P+
Sbjct: 8 ERLREDARCPVCLDFLQEPVSVDCGHSFCLRCISEFCEKSDGAQGGVYACPQCRGPFRPS 67
Query: 60 ALRPNWALARLTEKTQRRRLGPVPPGL-CGRHWEPLRLFCEDDQRPVCLVCRESQEHQTH 118
RPN LA L E +R LG P C RH E L FCE+D+ +C VC EH+TH
Sbjct: 68 GFRPNRQLAGLVESVRRLGLGAGPGARRCARHGEDLSRFCEEDEAALCWVCDAGPEHRTH 127
Query: 119 AMAPIDEAFESYRTGNFDIHVDEWKRRLIRLLLYHSKQEEKLLKSQRNLVAKMKKVMHLQ 178
AP+ EA SY+ +L L K+ E L + N+
Sbjct: 128 RTAPLQEAAGSYQV------------KLQMALELMRKELEDALTQEANVG---------- 165
Query: 179 DVEVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLK 238
K WK+K++ QR R EF K FL +EE L+RL EE T ++L E+ +
Sbjct: 166 ----KKTVIWKEKVEMQRQRFRLEFEKHRGFLAQEEQRQLRRLEAEERATLQRLRESKSR 221
Query: 239 LNQTIASLKKLILEVGEKSQAPTLELLQNPKEVLTRSE-IQDVNYSLEAVKVKTVCQIPL 297
L Q +LK+L E+ E+ Q P L LL+ + VL+RS+ + + +++KT C IP
Sbjct: 222 LVQQSKALKELADELQERCQRPALGLLEGVRGVLSRSKAVTRLEAENIPMELKTACCIPG 281
Query: 298 MKEMLKRFQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKT 357
+E+L++FQV V L TAHP L+ + + R V++ P NP
Sbjct: 282 RRELLRKFQVDVKLDPATAHPSLLLTADLRSVQDGEPWRDVP------------NNP--- 326
Query: 358 AFVERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCREDVMGITDRSKMSPDVGIW 417
ERF PC+LG F+SG+HYWEV + E +GVC +D + + SP+ G+W
Sbjct: 327 ---ERFDTWPCILGLQSFSSGRHYWEVLVGEGAEWGLGVC-QDTLPRKGETTPSPENGVW 382
Query: 418 AIYWSAAGYWPLIGFPGTPTQQEPALHRVGVYLDRGTGNVSFYSAVDGVHLHTFSCSSVS 477
A++ + ++ P P Q + +G++LD G +SFY+ DG +++TF+
Sbjct: 383 ALWLLKGNEYMVLASPSVPLLQLESPRCIGIFLDYEAGEISFYNVTDGSYIYTFNQLFSG 442
Query: 478 RLRPFFWLSPLASLVIPPVT 497
LRP+F++ L++PP T
Sbjct: 443 LLRPYFFICDATPLILPPTT 462
>gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens]
Length = 477
Score = 278 bits (711), Expect = 8e-75
Identities = 183/518 (35%), Positives = 264/518 (50%), Gaps = 75/518 (14%)
Query: 3 AEDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGP---------FPCPECR 53
A +QEE TC ICLDYF DPV CGHNFCR C+ +W G FPCPECR
Sbjct: 7 ARKLQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSFPCPECR 66
Query: 54 HPSAPAALRPNWALARLTEKTQRRRLGPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQ 113
S L PN L ++ E Q+ G LC H EPL+LFC+ DQ P+C+VCRES+
Sbjct: 67 EMSPQRNLLPNRLLTKVAEMAQQHP-GLQKQDLCQEHHEPLKLFCQKDQSPICVVCRESR 125
Query: 114 EHQTHAMAPIDEAFESYRTGNFDIHVDEWKRRLIRLLLYHSKQEEKLLKSQRNLVAKMKK 173
EH+ H + P +EA + Y+ KL + L ++ +
Sbjct: 126 EHRLHRVLPAEEAVQGYKL--------------------------KLEEDMEYLREQITR 159
Query: 174 VMHLQDVEVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLN 233
+LQ E ++ +W+ K+K +R RI EF K++ +LVEEE LQ L EEEET +L
Sbjct: 160 TGNLQAREEQSLAEWQGKVKERRERIVLEFEKMNLYLVEEEQRLLQALETEEEETASRLR 219
Query: 234 ENTLKLNQTIASLKKLILEVGEKSQAPTLELLQNPKEVLTRSEIQDVNYSLEAVKV---- 289
E+ L++ SL+ L+L++ E+S L++LQ+ KE L+R N S++ +V
Sbjct: 220 ESVACLDRQGHSLELLLLQLEERSTQGPLQMLQDMKEPLSRKN----NVSVQCPEVAPPT 275
Query: 290 --KTVCQIPLMKEMLKRFQVAVNLAEDTAHPKLVF--SQEGRYVKNTASASSWPVFSSAW 345
+TVC++P E+L+ F V +A+P L+ S++ RY+ ++ S +
Sbjct: 276 RPRTVCRVPGQIEVLRGFLEDVVPDATSAYPYLLLYESRQRRYLGSSPEGSGF------- 328
Query: 346 NYFAGWRNPQKTAFVERFQHLPCVLGKNVFTSGKHYWEVESRDSLEV--AVGVCREDVMG 403
+RF PC +G+ F+SG+HYWEV + + A+GVCR++V
Sbjct: 329 ------------CSKDRFVAYPCAVGQTAFSSGRHYWEVGMNITGDALWALGVCRDNV-S 375
Query: 404 ITDRSKMSPDVGIWAIYWSAAGYWPLIGFPGTPTQ-QEPALHRVGVYLDRGTGNVSFYSA 462
DR P+ G W + S + TP EP H +G++LD G VSFYS
Sbjct: 376 RKDRVPKCPENGFWVVQLSKGTKYLSTFSALTPVMLMEPPSH-MGIFLDFEAGEVSFYSV 434
Query: 463 VDGVHLHTFSCSSV-SRLRPFFWLSPLAS--LVIPPVT 497
DG HLHT+S ++ L+PFF L S +VI VT
Sbjct: 435 SDGSHLHTYSQATFPGPLQPFFCLGAPKSGQMVISTVT 472
>gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens]
Length = 477
Score = 278 bits (711), Expect = 8e-75
Identities = 183/518 (35%), Positives = 264/518 (50%), Gaps = 75/518 (14%)
Query: 3 AEDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGP---------FPCPECR 53
A +QEE TC ICLDYF DPV CGHNFCR C+ +W G FPCPECR
Sbjct: 7 ARKLQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSFPCPECR 66
Query: 54 HPSAPAALRPNWALARLTEKTQRRRLGPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQ 113
S L PN L ++ E Q+ G LC H EPL+LFC+ DQ P+C+VCRES+
Sbjct: 67 EMSPQRNLLPNRLLTKVAEMAQQHP-GLQKQDLCQEHHEPLKLFCQKDQSPICVVCRESR 125
Query: 114 EHQTHAMAPIDEAFESYRTGNFDIHVDEWKRRLIRLLLYHSKQEEKLLKSQRNLVAKMKK 173
EH+ H + P +EA + Y+ KL + L ++ +
Sbjct: 126 EHRLHRVLPAEEAVQGYKL--------------------------KLEEDMEYLREQITR 159
Query: 174 VMHLQDVEVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLN 233
+LQ E ++ +W+ K+K +R RI EF K++ +LVEEE LQ L EEEET +L
Sbjct: 160 TGNLQAREEQSLAEWQGKVKERRERIVLEFEKMNLYLVEEEQRLLQALETEEEETASRLR 219
Query: 234 ENTLKLNQTIASLKKLILEVGEKSQAPTLELLQNPKEVLTRSEIQDVNYSLEAVKV---- 289
E+ L++ SL+ L+L++ E+S L++LQ+ KE L+R N S++ +V
Sbjct: 220 ESVACLDRQGHSLELLLLQLEERSTQGPLQMLQDMKEPLSRKN----NVSVQCPEVAPPT 275
Query: 290 --KTVCQIPLMKEMLKRFQVAVNLAEDTAHPKLVF--SQEGRYVKNTASASSWPVFSSAW 345
+TVC++P E+L+ F V +A+P L+ S++ RY+ ++ S +
Sbjct: 276 RPRTVCRVPGQIEVLRGFLEDVVPDATSAYPYLLLYESRQRRYLGSSPEGSGF------- 328
Query: 346 NYFAGWRNPQKTAFVERFQHLPCVLGKNVFTSGKHYWEVESRDSLEV--AVGVCREDVMG 403
+RF PC +G+ F+SG+HYWEV + + A+GVCR++V
Sbjct: 329 ------------CSKDRFVAYPCAVGQTAFSSGRHYWEVGMNITGDALWALGVCRDNV-S 375
Query: 404 ITDRSKMSPDVGIWAIYWSAAGYWPLIGFPGTPTQ-QEPALHRVGVYLDRGTGNVSFYSA 462
DR P+ G W + S + TP EP H +G++LD G VSFYS
Sbjct: 376 RKDRVPKCPENGFWVVQLSKGTKYLSTFSALTPVMLMEPPSH-MGIFLDFEAGEVSFYSV 434
Query: 463 VDGVHLHTFSCSSV-SRLRPFFWLSPLAS--LVIPPVT 497
DG HLHT+S ++ L+PFF L S +VI VT
Sbjct: 435 SDGSHLHTYSQATFPGPLQPFFCLGAPKSGQMVISTVT 472
>gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]
Length = 488
Score = 253 bits (645), Expect = 4e-67
Identities = 164/510 (32%), Positives = 238/510 (46%), Gaps = 59/510 (11%)
Query: 4 EDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAALRP 63
E++Q E +C +CL+Y ++PV IECGHNFC+ C+ R W FPCP CR S +LRP
Sbjct: 21 ENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERDFPCPVCRKTSRYRSLRP 80
Query: 64 NWALARLTE---KTQRRRLGPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHAM 120
N L + E + Q + LC +H E L LFC +DQ VCL+C S H+ H +
Sbjct: 81 NRQLGSMVEIAKQLQAVKRKIRDESLCPQHHEALSLFCYEDQEAVCLICAISHTHRAHTV 140
Query: 121 APIDEAFESYRTGNFDIHVDEWKRRLIRLLLYHSKQEEKLLKSQRNLVAKMKKVMHLQDV 180
P+D+A + Y+ EKL K L K++++ +
Sbjct: 141 VPLDDATQEYK--------------------------EKLQKCLEPLEQKLQEITRCKSS 174
Query: 181 EVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLN 240
E K + K ++S+R +I EF +LH L EE+ + L RL +EE++ ++L EN L
Sbjct: 175 EEKKPGELKRLVESRRQQILREFEELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLG 234
Query: 241 QTIASLKKLILEVGEKSQAPTLELLQNPKEVLTR------SEIQDVNYSLEAVKVKTVCQ 294
L L EV K E+L++ K L + E+ V+ LE Q
Sbjct: 235 DKRRDLAHLAAEVEGKCLQSGFEMLKDVKSTLEKCEKVKTMEVTSVSIELEKNFSNFPRQ 294
Query: 295 IPLMKEMLKRFQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNP 354
++++LK+ V L +TAHP LV S++ + VK F R
Sbjct: 295 YFALRKILKQLIADVTLDPETAHPNLVLSEDRKSVK-----------------FVETRLR 337
Query: 355 QKTAFVERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCREDVMGITDRSKMSPDV 414
RF PCVL FTSG+HYWEVE D AVGVCR+ V + + + P+
Sbjct: 338 DLPDTPRRFTFYPCVLATEGFTSGRHYWEVEVGDKTHWAVGVCRDSVSRKGELTPL-PET 396
Query: 415 GIWAIYWSAAGYWPLIGFPGTPTQQEPALHRVGVYLDRGTGNVSFYSAVDGVHLHTFSCS 474
G W + + P TP + RVG++LD G +SFY+ D H++TF+ +
Sbjct: 397 GYWRVRLWNGDKYAATTTPFTPLHIKVKPKRVGIFLDYEAGTLSFYNVTDRSHIYTFTDT 456
Query: 475 SVSRLRPFFW------LSPLASLVIPPVTD 498
+L P F+ A L I P TD
Sbjct: 457 FTEKLWPLFYPGIRAGRKNAAPLTIRPPTD 486
>gi|15208660 tripartite motif protein 21 [Homo sapiens]
Length = 475
Score = 248 bits (632), Expect = 1e-65
Identities = 173/485 (35%), Positives = 245/485 (50%), Gaps = 59/485 (12%)
Query: 8 EELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAALRPNWAL 67
EE+TCPICLD F +PVSIECGH+FC+ C+ + GG CP CR LRPN L
Sbjct: 12 EEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSV--CPVCRQRFLLKNLRPNRQL 69
Query: 68 AR----LTEKTQRRRLGPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHAMAPI 123
A L E +Q R G C H E L LFCE D + +C VC +S++H+ HAM P+
Sbjct: 70 ANMVNNLKEISQEAREG-TQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVPL 128
Query: 124 DEAFESYRTGNFDIHVDEWKRRLIRLLLYHSKQEEKLLKSQRNLVAKMKKVMHLQ-DVEV 182
+EA + Y +EKL + L K + L+ ++ +
Sbjct: 129 EEAAQEY--------------------------QEKLQVALGELRRKQELAEKLEVEIAI 162
Query: 183 KNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQT 242
K A WK +++Q+ RI EF + NFLVEEE LQ L K+E E + L E KL Q
Sbjct: 163 KRA-DWKKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQ 221
Query: 243 IASLKKLILEVGEKSQAPTLELLQNPKEVLTRSEIQDV-NYSLEAVKVKTVCQIPLMKEM 301
+L++LI E+ + + LELLQ VL RSE ++ + + + ++++VC +P +K+M
Sbjct: 222 SQALQELISELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKM 281
Query: 302 LKRFQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVE 361
L+ V + L DTA+P L+ S++ R V+ + S P E
Sbjct: 282 LRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIP------------------GNEE 323
Query: 362 RFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIY- 420
RF P VLG F SGKHYWEV+ +GVCR+ V +S G W I+
Sbjct: 324 RFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRR-KGHFLLSSKSGFWTIWL 382
Query: 421 WSAAGYWPLIGFPGTPTQQEPALHRVGVYLDRGTGNVSFYSAVD-GVHLHTFS-CSSVSR 478
W+ Y +P TP + +VG++LD G VSFY+ D G +++FS C+
Sbjct: 383 WNKQKY-EAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGP 441
Query: 479 LRPFF 483
LRPFF
Sbjct: 442 LRPFF 446
>gi|68160935 tripartite motif-containing 17 isoform 2 [Homo sapiens]
Length = 450
Score = 247 bits (630), Expect = 2e-65
Identities = 168/494 (34%), Positives = 248/494 (50%), Gaps = 75/494 (15%)
Query: 27 CGHNFCRGCLHRNWAPGGGP---------FPCPECRHPSAPAALRPNWALARLTEKTQRR 77
CGHNFCR C+ +W G FPCPECR S L PN L ++ E Q+
Sbjct: 4 CGHNFCRACIQLSWEKARGKKGRRKRKGSFPCPECREMSPQRNLLPNRLLTKVAEMAQQH 63
Query: 78 RLGPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHAMAPIDEAFESYRTGNFDI 137
G LC H EPL+LFC+ DQ P+C+VCRES+EH+ H + P +EA + Y+
Sbjct: 64 P-GLQKQDLCQEHHEPLKLFCQKDQSPICVVCRESREHRLHRVLPAEEAVQGYKL----- 117
Query: 138 HVDEWKRRLIRLLLYHSKQEEKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRM 197
KL + L ++ + +LQ E ++ +W+ K+K +R
Sbjct: 118 ---------------------KLEEDMEYLREQITRTGNLQAREEQSLAEWQGKVKERRE 156
Query: 198 RISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKS 257
RI EF K++ +LVEEE LQ L EEEET +L E+ L++ SL+ L+L++ E+S
Sbjct: 157 RIVLEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSLELLLLQLEERS 216
Query: 258 QAPTLELLQNPKEVLTRSEIQDVNYSLEAVKV------KTVCQIPLMKEMLKRFQVAVNL 311
L++LQ+ KE L+R N S++ +V +TVC++P E+L+ F V
Sbjct: 217 TQGPLQMLQDMKEPLSRKN----NVSVQCPEVAPPTRPRTVCRVPGQIEVLRGFLEDVVP 272
Query: 312 AEDTAHPKLVF--SQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHLPCV 369
+A+P L+ S++ RY+ ++ S + +RF PC
Sbjct: 273 DATSAYPYLLLYESRQRRYLGSSPEGSGF-------------------CSKDRFVAYPCA 313
Query: 370 LGKNVFTSGKHYWEVESRDSLEV--AVGVCREDVMGITDRSKMSPDVGIWAIYWSAAGYW 427
+G+ F+SG+HYWEV + + A+GVCR++V DR P+ G W + S +
Sbjct: 314 VGQTAFSSGRHYWEVGMNITGDALWALGVCRDNV-SRKDRVPKCPENGFWVVQLSKGTKY 372
Query: 428 PLIGFPGTPTQ-QEPALHRVGVYLDRGTGNVSFYSAVDGVHLHTFSCSSV-SRLRPFFWL 485
TP EP H +G++LD G VSFYS DG HLHT+S ++ L+PFF L
Sbjct: 373 LSTFSALTPVMLMEPPSH-MGIFLDFEAGEVSFYSVSDGSHLHTYSQATFPGPLQPFFCL 431
Query: 486 SPLAS--LVIPPVT 497
S +VI VT
Sbjct: 432 GAPKSGQMVISTVT 445
>gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]
Length = 518
Score = 243 bits (620), Expect = 3e-64
Identities = 166/540 (30%), Positives = 242/540 (44%), Gaps = 89/540 (16%)
Query: 4 EDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAALRP 63
E++Q E +C +CL+Y ++PV IECGHNFC+ C+ R W FPCP CR S +LRP
Sbjct: 21 ENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERDFPCPVCRKTSRYRSLRP 80
Query: 64 NWALARLTE---KTQRRRLGPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHAM 120
N L + E + Q + LC +H E L LFC +DQ VCL+C S H+ H +
Sbjct: 81 NRQLGSMVEIAKQLQAVKRKIRDESLCPQHHEALSLFCYEDQEAVCLICAISHTHRAHTV 140
Query: 121 APIDEAFESYRTGNFDIHVDEWKRRLIRLLLYHSKQEEKLLKSQRNLVAKMKKVMHLQDV 180
P+D+A + Y+ EKL K L K++++ +
Sbjct: 141 VPLDDATQEYK--------------------------EKLQKCLEPLEQKLQEITRCKSS 174
Query: 181 EVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLN 240
E K + K ++S+R +I EF +LH L EE+ + L RL +EE++ ++L EN L
Sbjct: 175 EEKKPGELKRLVESRRQQILREFEELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLG 234
Query: 241 QTIASLKKLILEVGEKSQAPTLELLQNPKEVLTRSEIQDVNYSLEAV------------- 287
L L EV K E+L++ K L ++ + SL +
Sbjct: 235 DKRRDLAHLAAEVEGKCLQSGFEMLKDVKSTLEKNIPRKFGGSLSTICPRDHKALLGLVK 294
Query: 288 ------KVKTV-----------------CQIPLMKEMLKRFQVAVNLAEDTAHPKLVFSQ 324
KVKT+ Q ++++LK+ V L +TAHP LV S+
Sbjct: 295 EINRCEKVKTMEVTSVSIELEKNFSNFPRQYFALRKILKQLIADVTLDPETAHPNLVLSE 354
Query: 325 EGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHLPCVLGKNVFTSGKHYWEV 384
+ + VK F R RF PCVL FTSG+HYWEV
Sbjct: 355 DRKSVK-----------------FVETRLRDLPDTPRRFTFYPCVLATEGFTSGRHYWEV 397
Query: 385 ESRDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIYWSAAGYWPLIGFPGTPTQQEPALH 444
E D AVGVCR+ V + + + P+ G W + + P TP +
Sbjct: 398 EVGDKTHWAVGVCRDSVSRKGELTPL-PETGYWRVRLWNGDKYAATTTPFTPLHIKVKPK 456
Query: 445 RVGVYLDRGTGNVSFYSAVDGVHLHTFSCSSVSRLRPFFW------LSPLASLVIPPVTD 498
RVG++LD G +SFY+ D H++TF+ + +L P F+ A L I P TD
Sbjct: 457 RVGIFLDYEAGTLSFYNVTDRSHIYTFTDTFTEKLWPLFYPGIRAGRKNAAPLTIRPPTD 516
>gi|5730009 ret finger protein [Homo sapiens]
Length = 513
Score = 241 bits (616), Expect = 9e-64
Identities = 171/536 (31%), Positives = 251/536 (46%), Gaps = 90/536 (16%)
Query: 3 AEDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAALR 62
AE +Q+E TCP+CL YF +P+ ++CGHN C CL R W CP+CR +R
Sbjct: 7 AECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTAETNVSCPQCRETFPQRHMR 66
Query: 63 PNWALARLTEKT-QRRRLGPVPP----GLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQT 117
PN LA +T+ Q R P P G+C +H EPL+L+CE+DQ P+C+VC S+EH+
Sbjct: 67 PNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICVVCDRSREHRG 126
Query: 118 HAMAPIDEAFESYRTGNFDIHVDEWKRRLIRLLLYHSKQEEKLLKSQRNLVAKMKKVMHL 177
H++ P++EA E + + I+ L H K+ + L K +R + +
Sbjct: 127 HSVLPLEEAVEGF-------------KEQIQNQLDHLKRVKDLKKRRRAQGEQAR----- 168
Query: 178 QDVEVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTL 237
E+ + TQ +R +I EF +L++ L E E L RL + + +N
Sbjct: 169 --AELLSLTQ------MEREKIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAIT 220
Query: 238 KLNQTIASLKKLILEVGEKSQAPTLELLQNPKEVLTRSE----------IQDVNYSLEAV 287
+ + I+ L LI ++ EK Q PT ELLQ+ + L+R+E D+ +
Sbjct: 221 QFSCNISHLSSLIAQLEEKQQQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIF 280
Query: 288 KVKTVCQIPLMKEMLKRFQ----------------VAVNLAEDTAHPKLVFSQEGRYVKN 331
K + +K+ ++ Q V V L DTA+P L+ S R V+
Sbjct: 281 AQKCLFLTESLKQFTEKMQSDMEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRY 340
Query: 332 TASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHLPCVLGKNVFTSGKHYWEVESRDSLE 391
+ P NP ERF PCVLG F +G+HYWEVE D +
Sbjct: 341 SYLQQDLP------------DNP------ERFNLFPCVLGSPCFIAGRHYWEVEVGDKAK 382
Query: 392 VAVGVCREDVM---GITDRSKMSPDVGIWAI-YWSAAGYWPLIGFPGTPTQQEPALHRVG 447
+GVC + V G+T +P G WA+ W YW L P T L RVG
Sbjct: 383 WTIGVCEDSVCRKGGVTS----APQNGFWAVSLWYGKEYWALTS-PMTALPLRTPLQRVG 437
Query: 448 VYLDRGTGNVSFYSAVDGVHLHTFS-CSSVSRLRPFFWLS-----PLASLVIPPVT 497
++LD G VSFY+ + H TFS + +RP+F LS A L+I P++
Sbjct: 438 IFLDYDAGEVSFYNVTERCHTFTFSHATFCGPVRPYFSLSYSGGKSAAPLIICPMS 493
>gi|157743261 tripartite motif-containing 75 [Homo sapiens]
Length = 468
Score = 241 bits (614), Expect = 1e-63
Identities = 156/493 (31%), Positives = 247/493 (50%), Gaps = 59/493 (11%)
Query: 6 IQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAALRPNW 65
+Q E C ICLDY DPV+IECGHNFCR C+ ++W FPCP CRH R N
Sbjct: 10 LQAEAKCSICLDYLSDPVTIECGHNFCRSCIQQSWLDLQELFPCPVCRHQCQEGHFRSNT 69
Query: 66 AL------ARLTEKTQRRRLGPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHA 119
L A+L + T+ + LC +H +PL +FC++D +C +C + +HQ H
Sbjct: 70 QLGRMIEIAKLLQSTKSNKRKQEETTLCEKHNQPLSVFCKEDLMVLCPLCTQPPDHQGHH 129
Query: 120 MAPIDEAFESYRTGNFDIHVDEWKRRLIRLLLYHSKQEEKLLKSQRNLVAKMKKVMHLQD 179
+ PI++A YR F ++ K++L L +KL+ +Q KK + L++
Sbjct: 130 VRPIEKAAIHYRK-RFCSYIQPLKKQLADL--------QKLISTQ------SKKPLELRE 174
Query: 180 VEVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKL 239
+ +++QR +S+EF L+ FL E+ L RL +EE++ ++KL+ N
Sbjct: 175 M-----------VENQRQELSSEFEHLNQFLDREQQAVLSRLAEEEKDNQQKLSANITAF 223
Query: 240 NQTIASLKKLILEVGEKSQAPTLELLQNPKEVLTRSEIQDVNYSLEAVKVK-TVCQIP-- 296
+ A+LK + +V E S+ LELL K + SE + + S+ ++ +K C P
Sbjct: 224 SNYSATLKSQLSKVVELSELSELELLSQIK-IFYESE-NESSPSIFSIHLKRDGCSFPPQ 281
Query: 297 --LMKEMLKRFQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNP 354
++ ++K+F+V + L +TAHP L+ S++ + V+ T R
Sbjct: 282 YSALQRIIKKFKVEIILDPETAHPNLIVSEDKKRVRFTK------------------RKQ 323
Query: 355 QKTAFVERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCREDVMGITDRSKMSPDV 414
+ F +RF P VLG F SG+H+WE+E D E A+G+C+ D + R S
Sbjct: 324 KVPGFPKRFTVKPVVLGFPYFHSGRHFWEIEVGDKSEWAIGICK-DSLPTKARRPSSAQQ 382
Query: 415 GIWAIYWSAAGYWPLIGFPGTPTQQEPALHRVGVYLDRGTGNVSFYSAVDGVHLHTFSCS 474
W I GY FP TP E +G++LD G +SFY+ + H+ TF+ +
Sbjct: 383 ECWRIELQDDGYHAPGAFP-TPLLLEVKARAIGIFLDYEMGEISFYNMAEKSHICTFTDT 441
Query: 475 SVSRLRPFFWLSP 487
LRP+F++ P
Sbjct: 442 FTGPLRPYFYVGP 454
>gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens]
Length = 511
Score = 237 bits (605), Expect = 2e-62
Identities = 171/537 (31%), Positives = 255/537 (47%), Gaps = 114/537 (21%)
Query: 3 AEDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNW-APGGG-----------PFPCP 50
A ++Q E TC ICL+ F++PVS+ECGH+FCR C+ R W PG G P PCP
Sbjct: 20 AAELQGEATCSICLELFREPVSVECGHSFCRACIGRCWERPGAGSVGAATRAPPFPLPCP 79
Query: 51 ECRHPSAPAALRPNWALARLTEKTQRRRLGPVPPG--------------LCGRHWEPLRL 96
+CR P+ P+ LRPN LA + +R L PG CG+H EP +L
Sbjct: 80 QCREPARPSQLRPNRQLAAVATLLRRFSLPAAAPGEHGSQAAAARAAAARCGQHGEPFKL 139
Query: 97 FCEDDQRPVCLVCRESQEHQTHAMAPIDEAFESYRTGNFDIHVDEWKRRLIRLLLYHSKQ 156
+C+DD R +C+VC ++EH+ HA+ P+DEA + +
Sbjct: 140 YCQDDGRAICVVCDRAREHREHAVLPLDEAVQ---------------------------E 172
Query: 157 EEKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKD------KIKSQRMRISTEFSKLHNFL 210
++LL+S+ ++ K L+D EV +T+ K+ ++ +++ ++ EF L FL
Sbjct: 173 AKELLESRLRVLKK-----ELEDCEVFRSTEKKESKELLKQMAAEQEKVGAEFQALRAFL 227
Query: 211 VEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAPTLELLQNPKE 270
VE+E L RL + E +K NEN +L I L KL ++ E +Q P L+ LQ K
Sbjct: 228 VEQEGRLLGRLEELSREVAQKQNENLAQLGVEITQLSKLSSQIQETAQKPDLDFLQEFKS 287
Query: 271 VLTR-------------SEIQDV--NYSLEAVKVKTVC---QIPLMKEMLKRFQVAVNLA 312
L+R SE+++ N SL+ +K + + L E+ K +V + L
Sbjct: 288 TLSRCSNVPGPKPTTVSSEMKNKVWNVSLKTFVLKGMLKKFKEDLRGELEKEEKVELTLD 347
Query: 313 EDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHLPCVLGK 372
DTA+P+L+ S + + V+ A P RF VL
Sbjct: 348 PDTANPRLILSLDLKGVRLGERAQDLPNHPC------------------RFDTNTRVLAS 389
Query: 373 NVFTSGKHYWEVESRDSLEVAVGVCREDV--MGITDRSKMSPDVGIWAIYWSAAGYWPLI 430
F+SG+H+WEVE A GV RE V G+T +P+ G+WA+ + YW +
Sbjct: 390 CGFSSGRHHWEVEVGSKDGWAFGVARESVRRKGLT---PFTPEEGVWALQLNGGQYWAV- 445
Query: 431 GFPGTPTQQEPA----LHRVGVYLDRGTGNVSFYSAVDGVHLHTFSCSSVSRLRPFF 483
T ++ P L RV V LD G VSFY+ D HL+TF + R+ P F
Sbjct: 446 ----TSPERSPLSCGHLSRVRVALDLEVGAVSFYAVEDMRHLYTFRVNFQERVFPLF 498
>gi|37622899 ring finger protein 137 [Homo sapiens]
Length = 485
Score = 232 bits (591), Expect = 7e-61
Identities = 166/522 (31%), Positives = 256/522 (49%), Gaps = 95/522 (18%)
Query: 4 EDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNW-APGGGP---FPCPECRHPSAPA 59
E I EE+ CPIC+ + ++P+SI+CGH+FC CL W PG + CP CR P P
Sbjct: 8 EAIVEEVACPICMTFLREPMSIDCGHSFCHSCLSGLWEIPGESQNWGYTCPLCRAPVQPR 67
Query: 60 ALRPNWALARLTEKTQRRRLGP---VPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQ 116
LRPNW LA + EK + RL P + LC RH E L++FC++D +C C +S EH+
Sbjct: 68 NLRPNWQLANVVEKVRLLRLHPGMGLKGDLCERHGEKLKMFCKEDVLIMCEACSQSPEHE 127
Query: 117 THAMAPIDEAFESYRTGNFDIHVDEWKRRLIRLLLYHSKQEEKLLKSQRNLVAKMKKVMH 176
H++ P+++ Y+ W+ + L H K+E+ ++
Sbjct: 128 AHSVVPMEDVAWEYK----------WE---LHEALEHLKKEQ-------------EEAWK 161
Query: 177 LQDVEVKNATQWKDKIKSQRMRISTEFSKL----------HNFLVEEEDLFLQRLNKEEE 226
L+ E K WK ++++++ I EF K H L E L L +E
Sbjct: 162 LEVGERKRTATWKIQVETRKQSIVWEFEKYQRLLEKKQPPHRQLGAEVAAALASLQREAA 221
Query: 227 ETKKKLNENTLKLNQTIASLKKLILEVGEKSQAPTLELLQNPKEVLTRSEIQDVNYSLE- 285
ET +KL N +L Q L ++I E+ E+SQ P +LQ+ +EVL RS+ ++SL+
Sbjct: 222 ETMQKLELNHSELIQQSQVLWRMIAELKERSQRPVRWMLQDIQEVLNRSK----SWSLQQ 277
Query: 286 ----AVKVKTVCQIPLMKEMLKRFQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVF 341
++++KT C++ ++E+LK + V L DTA+ +L+ S++ + V + P
Sbjct: 278 PEPISLELKTDCRVLGLREILKTYAADVRLDPDTAYSRLIVSEDRKRVHYGDTNQKLP-- 335
Query: 342 SSAWNYFAGWRNPQKTAFVERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCREDV 401
NP ERF VLG +SG+HYWEVE D E +GVC+++V
Sbjct: 336 ----------DNP------ERFYRYNIVLGSQCISSGRHYWEVEVGDRSEWGLGVCKQNV 379
Query: 402 MGITDRSK---MSPDVGIWAI-------YWSAAGYWPLIGFPGTPTQQEPALHRVGVYLD 451
DR + +SP G W I Y + +P++ P P RVG+++D
Sbjct: 380 ----DRKEVVYLSPHYGFWVIRLRKGNEYRAGTDEYPILSLPVPP-------RRVGIFVD 428
Query: 452 RGTGNVSFYSAVD-GVHLHTF-SCSSVSRLRPFFWLSPLASL 491
++SFY+ D G H+ TF RL P+F SP S+
Sbjct: 429 YEAHDISFYNVTDCGSHIFTFPRYPFPGRLLPYF--SPCYSI 468
>gi|5454014 tripartite motif-containing 38 [Homo sapiens]
Length = 465
Score = 220 bits (560), Expect = 3e-57
Identities = 161/507 (31%), Positives = 232/507 (45%), Gaps = 65/507 (12%)
Query: 6 IQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGP------FPCPECRHPSAPA 59
+ EE TC ICL +PVSI CGH++C C+ + F CP+CR P
Sbjct: 10 MMEEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQETFCCPQCRAPFHMD 69
Query: 60 ALRPNWALARLTEKTQRRRLGPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHA 119
+LRPN L L E + C H E LFCED+ + +C C + +H+ H
Sbjct: 70 SLRPNKQLGSLIEALKETD----QEMSCEEHGEQFHLFCEDEGQLICWRCERAPQHKGHT 125
Query: 120 MAPIDEAFESYRTGNFDIHVDEWKRRLIRLLLYHSKQEEKLLKSQRNLVAKMKKVMHLQD 179
A +++ + Y+ EKL K+ L + +
Sbjct: 126 TALVEDVCQGYK--------------------------EKLQKAVTKLKQLEDRCTEQKL 159
Query: 180 VEVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKL 239
T+WK+K++ QR +I ++F L FL EEE +L RL KEE++T +L + L
Sbjct: 160 STAMRITKWKEKVQIQRQKIRSDFKNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGL 219
Query: 240 NQTIASLKKLILEVGEKSQAPTLELLQNPKEVLTRSEIQDVNYSLEAVKVK--TVCQIPL 297
LK ILE+ EK Q +LLQN + L+RS + S EAV ++ T+C +
Sbjct: 220 GLKSNELKSHILELEEKCQGSAQKLLQNVNDTLSRSWAVKLETS-EAVSLELHTMCNVSK 278
Query: 298 M----KEMLKRFQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRN 353
+ K+ML+ QV+V L DTAH +L+ S++ R V G+
Sbjct: 279 LYFDVKKMLRSHQVSVTLDPDTAHHELILSEDRRQVTR------------------GYTQ 320
Query: 354 PQKTAFVERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCREDVMGITDRSKMSPD 413
+ RF PCVLG FTSG+ Y+EV+ + +GVC E+V T K P
Sbjct: 321 ENQDTSSRRFTAFPCVLGCEGFTSGRRYFEVDVGEGTGWDLGVCMENVQRGTG-MKQEPQ 379
Query: 414 VGIWAI-YWSAAGYWPLIGFPGTPTQQEPALHRVGVYLDRGTGNVSFYSAVDGVHLHTFS 472
G W + GY L P + E L VG++LD G VSFY+ G H+ TF
Sbjct: 380 SGFWTLRLCKKKGYVALTSPPTSLHLHEQPL-LVGIFLDYEAGVVSFYNGNTGCHIFTFP 438
Query: 473 CSSVS-RLRPFFWLSPLASLVIPPVTD 498
+S S LRP+F + + L +PP D
Sbjct: 439 KASFSDTLRPYFQVYQYSPLFLPPPGD 465
>gi|22749269 ring finger protein 129 [Homo sapiens]
Length = 471
Score = 209 bits (532), Expect = 5e-54
Identities = 152/494 (30%), Positives = 242/494 (48%), Gaps = 63/494 (12%)
Query: 5 DIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAALRPN 64
++QEE +CPICL+Y +DPV+I CGHNFCR CL +W FPCP CR + R N
Sbjct: 9 NLQEESSCPICLEYLKDPVTINCGHNFCRSCLSVSWKDLDDTFPCPVCRFCFPYKSFRRN 68
Query: 65 WALARLTEKTQR------RRLGPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQTH 118
L LTE ++ +R +C +H + L LFC D +C C S +HQ H
Sbjct: 69 PQLRNLTEIAKQLQIRRSKRKRQKENAMCEKHNQFLTLFCVKDLEILCTQCSFSTKHQKH 128
Query: 119 AMAPIDEAFESYRTGNFDIHVDEWKRRLIRLLLYHSKQEEKLLKSQRNLVAKMKKVMHLQ 178
+ PI +A YH + E L+ RN + +++KV+ LQ
Sbjct: 129 YICPIKKAAS-----------------------YHREILEGSLEPLRNNIERVEKVIILQ 165
Query: 179 DVEVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLK 238
+ + K K++ +R I++EF ++ FL E+++ L+++ EE KLNEN ++
Sbjct: 166 G---SKSVELKKKVEYKREEINSEFEQIRLFLQNEQEMILRQIQDEEMNILAKLNENLVE 222
Query: 239 LNQTIASLKKLILEVGEKSQAPTLELLQNPKEVLTRSE----IQDVNYSLEAVKVKTVCQ 294
L+ +++LK L+ EV KS LELL K + + + + ++ L Q
Sbjct: 223 LSDYVSTLKHLLREVEGKSVQSNLELLTQAKSMHHKYQNLKCPELFSFRLTKYGFSLPPQ 282
Query: 295 IPLMKEMLKRFQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNP 354
+ ++K FQV V L +TAHP+L+ S++ + V+ R
Sbjct: 283 YSGLDRIIKPFQVDVILDLNTAHPQLLVSEDRKAVRYE-------------------RKK 323
Query: 355 QKTAF-VERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCREDVMGITDRSKMSPD 413
+ + RF P VLG F+SG+HYWEVE + + +GVC +D + + + S
Sbjct: 324 RNICYDPRRFYVCPAVLGSQRFSSGRHYWEVEVGNKPKWILGVC-QDCLLRNWQDQPSVL 382
Query: 414 VGIWAI-YWSAAGYWPLIGFPGTPTQQEPAL--HRVGVYLDRGTGNVSFYSAVDGVHLHT 470
G WAI + +GY + P T TQ P + ++G++LD G++SFY+ D L+T
Sbjct: 383 GGFWAIGRYMKSGY--VASGPKT-TQLLPVVKPSKIGIFLDYELGDLSFYNMNDRSILYT 439
Query: 471 FSCSSVSRLRPFFW 484
F+ + P+F+
Sbjct: 440 FNDCFTEAVWPYFY 453
>gi|198442878 tripartite motif-containing 17 isoform 3 [Homo
sapiens]
Length = 343
Score = 206 bits (524), Expect = 4e-53
Identities = 119/318 (37%), Positives = 170/318 (53%), Gaps = 46/318 (14%)
Query: 3 AEDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGP---------FPCPECR 53
A +QEE TC ICLDYF DPV CGHNFCR C+ +W G FPCPECR
Sbjct: 7 ARKLQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSFPCPECR 66
Query: 54 HPSAPAALRPNWALARLTEKTQRRRLGPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQ 113
S L PN L ++ E Q+ G LC H EPL+LFC+ DQ P+C+VCRES+
Sbjct: 67 EMSPQRNLLPNRLLTKVAEMAQQHP-GLQKQDLCQEHHEPLKLFCQKDQSPICVVCRESR 125
Query: 114 EHQTHAMAPIDEAFESYRTGNFDIHVDEWKRRLIRLLLYHSKQEEKLLKSQRNLVAKMKK 173
EH+ H + P +EA + Y+ KL + L ++ +
Sbjct: 126 EHRLHRVLPAEEAVQGYKL--------------------------KLEEDMEYLREQITR 159
Query: 174 VMHLQDVEVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLN 233
+LQ E ++ +W+ K+K +R RI EF K++ +LVEEE LQ L EEEET +L
Sbjct: 160 TGNLQAREEQSLAEWQGKVKERRERIVLEFEKMNLYLVEEEQRLLQALETEEEETASRLR 219
Query: 234 ENTLKLNQTIASLKKLILEVGEKSQAPTLELLQNPKEVLTRSEIQDVNYSLEAVKV---- 289
E+ L++ SL+ L+L++ E+S L++LQ+ KE L+R N S++ +V
Sbjct: 220 ESVACLDRQGHSLELLLLQLEERSTQGPLQMLQDMKEPLSRKN----NVSVQCPEVAPPT 275
Query: 290 --KTVCQIPLMKEMLKRF 305
+TVC++P E+L+ F
Sbjct: 276 RPRTVCRVPGQIEVLRGF 293
>gi|20270353 tripartite motif-containing 43 [Homo sapiens]
Length = 446
Score = 203 bits (517), Expect = 3e-52
Identities = 145/487 (29%), Positives = 222/487 (45%), Gaps = 63/487 (12%)
Query: 7 QEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAALRPNWA 66
Q+ELTC ICL+Y DPV+I CGH+FCR CL +W P CP CR PS + N
Sbjct: 10 QKELTCVICLNYLVDPVTICCGHSFCRPCLCLSWEEAQSPANCPACREPSPKMDFKTNIL 69
Query: 67 LARLTEKTQRRRLGPV---PPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHAMAPI 123
L L ++ L +CG H + ++FC+ D+ +CL+C SQEH H PI
Sbjct: 70 LKNLVTIARKASLWQFLSSEKQICGTHRQTKKMFCDMDKSLLCLLCSNSQEHGAHKHHPI 129
Query: 124 DEAFESYRTGNFDIHVDEWKRRLIRLLLYHSKQEEKLLKSQRNLVAKMKKVMHLQDVEVK 183
+EA E +R EKLLK R L K+++ E +
Sbjct: 130 EEAAEEHR--------------------------EKLLKQMRILWKKIQENQRNLYEEGR 163
Query: 184 NATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTI 243
A W+ + + I E+ KLH L +EE L+RLNKE +E ++L + +K++Q
Sbjct: 164 TAFLWRGNVVLRAQMIRNEYRKLHPVLHKEEKQHLERLNKEYQEIFQQLQRSWVKMDQKS 223
Query: 244 ASLKKLILEVGEKSQAPTLELLQNPKEVLTRSEIQDVNYSLEAVKVKTVCQIPLMKEMLK 303
LK++ E+ E P +ELLQ+ +++ RSE ++ T I + L
Sbjct: 224 KHLKEMYQELMEMCHKPDVELLQDLGDIVARSESVLLHMPQPVNPELTAGPITGLVYRLN 283
Query: 304 RFQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSW-----PVFSSAWNYFAGWRNPQKTA 358
RF+V ++ + + + ++ R SW P+ S +YFA W
Sbjct: 284 RFRVEISFHFEVTNHNIRLFEDVR---------SWMFRRGPLNSDRSDYFAAW------- 327
Query: 359 FVERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCREDVMGITDRSKMSPDVGIWA 418
G VF+ GKHYWE++ +S + A+GVC + S D+ +
Sbjct: 328 ------------GARVFSFGKHYWELDVDNSCDWALGVCNNSWIRKNSTMVNSEDIFLLL 375
Query: 419 IYWSAAGYWPLIGFPGTPTQQEPALHRVGVYLDRGTGNVSFYSAVDGVHLHTFSCSSVS- 477
+ L P P E L RVGV+LD +G+VSF + + ++ S++
Sbjct: 376 CLKVDNHFNLLTTSPVFPHYIEKPLGRVGVFLDFESGSVSFLNVTKSSLIWSYPAGSLTF 435
Query: 478 RLRPFFW 484
+RPFF+
Sbjct: 436 PVRPFFY 442
>gi|31542779 tripartite motif family-like 1 [Homo sapiens]
Length = 468
Score = 202 bits (515), Expect = 4e-52
Identities = 144/485 (29%), Positives = 221/485 (45%), Gaps = 52/485 (10%)
Query: 4 EDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAALRP 63
E+++EELTC ICLDYF PV+ ECGH+FC CL R+W P CPEC +
Sbjct: 8 ENLREELTCFICLDYFSSPVTTECGHSFCLVCLLRSWEEHNTPLSCPECWRTLEGPHFQS 67
Query: 64 NWALARLTEKTQRRRLGPV----PPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHA 119
N L RL ++ R + G GR + +D+Q V + ++ H
Sbjct: 68 NERLGRLASIARQLRSQVLQSEDEQGSYGRMPTTAKALSDDEQGGSAFVAQSHGANRVHL 127
Query: 120 MAPIDEAFESYRTGNFDIHVDEWKRRLIRLLLYHSKQEEKLLKSQRNLVAKMKKVMHLQD 179
+ +E H E + ++ LL K+ + +L ++ V
Sbjct: 128 SSEAEE------------HHREKLQEILNLLRVRRKEAQAVLTHEKERVKLC-------- 167
Query: 180 VEVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKL 239
+++ K+ + + +E+ K+H FL EEE L LQ L +EE+E +KL N +KL
Sbjct: 168 ---------QEETKTCKQVVVSEYMKMHQFLKEEEQLQLQLLEQEEKENMRKLRNNEIKL 218
Query: 240 NQTIASLKKLILEVGEKSQAPTLELLQNPKEVLTRSEIQDVNYSLEAVKVKTVCQIPLMK 299
Q I SL K+I ++ SQ+ E L+ + L RSE + ++C+I MK
Sbjct: 219 TQQIRSLSKMIAQIESSSQSSAFESLEEVRGALERSEPLLLQCPEATTTELSLCRITGMK 278
Query: 300 EMLKRFQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAF 359
EML++F + L TA+ LV S++ + VK S P NP
Sbjct: 279 EMLRKFSTEITLDPATANAYLVLSEDLKSVKYGGSRQQLP------------DNP----- 321
Query: 360 VERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCREDVMGITDRSKMSPDVGIWAI 419
ERF VLG +FTSG+HYWEVE + E VG+C++ V + K D+
Sbjct: 322 -ERFDQSATVLGTQIFTSGRHYWEVEVGNKTEWEVGICKDSVSRKGNLPKPPGDLFSLIG 380
Query: 420 YWSAAGYWPLIGFPGTPTQQEPALHRVGVYLDRGTGNVSFYSAVDGVHLHTFSCSSVSR- 478
Y + P + +VGV+LD +G+++FY+ D +++F +S
Sbjct: 381 LKIGDDYSLWVSSPLKGQHVREPVCKVGVFLDYESGHIAFYNGTDESLIYSFPQASFQEA 440
Query: 479 LRPFF 483
LRP F
Sbjct: 441 LRPIF 445
>gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens]
Length = 488
Score = 201 bits (510), Expect = 2e-51
Identities = 148/501 (29%), Positives = 235/501 (46%), Gaps = 81/501 (16%)
Query: 5 DIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPG----GGPFPCPECRHPSAPAA 60
DI+EE+TCPICL+ +P+SI+CGH+FC+ C+ N G CP C+ P
Sbjct: 8 DIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQPGN 67
Query: 61 LRPNWALARLTEKTQRRRLGP---VPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQT 117
LRPN LA + + + LGP + LC H E L+LFC++D + +C +C SQEH+
Sbjct: 68 LRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRG 127
Query: 118 HAMAPIDEAFESYRTGNFDIHVDEWKRRLIRLLLYHSKQEEKLLKSQRNLVAKMKKVMHL 177
H ++E + Y +EK +S + L + ++ L
Sbjct: 128 HHTFLVEEVAQEY--------------------------QEKFQESLKKLKNEEQEAEKL 161
Query: 178 QDVEVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTL 237
+ T WK++++ +R RI TEF++L N L E L++L +EE++ + + E
Sbjct: 162 TAFIREKKTSWKNQMEPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAEN 221
Query: 238 KLNQTIASLKKLILEVGEKSQAPTLELLQNPKEVLTRSEIQDVNYSLEAV--KVKTVCQI 295
L SL++LI ++ + Q T+ELLQ+ +V RSE + EA+ K++++ +
Sbjct: 222 DLVHQTQSLRELISDLERRCQGSTMELLQDVSDVTERSEFWTLR-KPEALPTKLRSMFRA 280
Query: 296 PLMKEMLK---------RFQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWN 346
P +K ML+ + V V L TA+ LV ++ R V+ + S P
Sbjct: 281 PDLKRMLRVCRELTDVQSYWVDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGP------- 333
Query: 347 YFAGWRNPQKTAFVERFQHLPC-VLGKNVFTSGKHYWEVESRDSLEVAVGVCREDVMGIT 405
+ +E+ H C VLG F+SGKHYWEV+ +GVC +
Sbjct: 334 -----------SCLEK--HYDCSVLGSQHFSSGKHYWEVDVAKKTAWILGVCSNSLGPTF 380
Query: 406 DRSKMSPDVGIWAIYWSAAGYWPLIGF-------------PGTPTQQEPALHRVGVYLDR 452
+ + + ++ Y +GYW +IG P RVGV+LD
Sbjct: 381 SFNHFAQNHSAYSRYQPQSGYW-VIGLQHNHEYRAYEDSSPSLLLSMTVPPRRVGVFLDY 439
Query: 453 GTGNVSFYSAVD-GVHLHTFS 472
G VSFY+ + G ++TFS
Sbjct: 440 EAGTVSFYNVTNHGFPIYTFS 460
>gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens]
Length = 516
Score = 201 bits (510), Expect = 2e-51
Identities = 148/501 (29%), Positives = 235/501 (46%), Gaps = 81/501 (16%)
Query: 5 DIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPG----GGPFPCPECRHPSAPAA 60
DI+EE+TCPICL+ +P+SI+CGH+FC+ C+ N G CP C+ P
Sbjct: 36 DIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQPGN 95
Query: 61 LRPNWALARLTEKTQRRRLGP---VPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQT 117
LRPN LA + + + LGP + LC H E L+LFC++D + +C +C SQEH+
Sbjct: 96 LRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRG 155
Query: 118 HAMAPIDEAFESYRTGNFDIHVDEWKRRLIRLLLYHSKQEEKLLKSQRNLVAKMKKVMHL 177
H ++E + Y +EK +S + L + ++ L
Sbjct: 156 HHTFLVEEVAQEY--------------------------QEKFQESLKKLKNEEQEAEKL 189
Query: 178 QDVEVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTL 237
+ T WK++++ +R RI TEF++L N L E L++L +EE++ + + E
Sbjct: 190 TAFIREKKTSWKNQMEPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAEN 249
Query: 238 KLNQTIASLKKLILEVGEKSQAPTLELLQNPKEVLTRSEIQDVNYSLEAV--KVKTVCQI 295
L SL++LI ++ + Q T+ELLQ+ +V RSE + EA+ K++++ +
Sbjct: 250 DLVHQTQSLRELISDLERRCQGSTMELLQDVSDVTERSEFWTLR-KPEALPTKLRSMFRA 308
Query: 296 PLMKEMLK---------RFQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWN 346
P +K ML+ + V V L TA+ LV ++ R V+ + S P
Sbjct: 309 PDLKRMLRVCRELTDVQSYWVDVTLNPHTANLNLVLAKNRRQVRFVGAKVSGP------- 361
Query: 347 YFAGWRNPQKTAFVERFQHLPC-VLGKNVFTSGKHYWEVESRDSLEVAVGVCREDVMGIT 405
+ +E+ H C VLG F+SGKHYWEV+ +GVC +
Sbjct: 362 -----------SCLEK--HYDCSVLGSQHFSSGKHYWEVDVAKKTAWILGVCSNSLGPTF 408
Query: 406 DRSKMSPDVGIWAIYWSAAGYWPLIGF-------------PGTPTQQEPALHRVGVYLDR 452
+ + + ++ Y +GYW +IG P RVGV+LD
Sbjct: 409 SFNHFAQNHSAYSRYQPQSGYW-VIGLQHNHEYRAYEDSSPSLLLSMTVPPRRVGVFLDY 467
Query: 453 GTGNVSFYSAVD-GVHLHTFS 472
G VSFY+ + G ++TFS
Sbjct: 468 EAGTVSFYNVTNHGFPIYTFS 488
>gi|157426898 tripartite motif-containing 10 isoform 1 [Homo
sapiens]
Length = 481
Score = 197 bits (500), Expect = 2e-50
Identities = 145/507 (28%), Positives = 229/507 (45%), Gaps = 73/507 (14%)
Query: 6 IQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFP----CPECRHPSAPAAL 61
+ +E+ CPIC ++PV+I+CGHNFCR CL R G CP C+ P P +
Sbjct: 10 LADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLCKEPFRPGSF 69
Query: 62 RPNWALARLTEKTQRRRL----GPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQT 117
RPNW LA + E +R +L G +C H E + FCEDD+ +C+VCRE+ EH T
Sbjct: 70 RPNWQLANVVENIERLQLVSTLGLGEEDVCQEHGEKIYFFCEDDEMQLCVVCREAGEHAT 129
Query: 118 HAMAPIDEAFESYRTGNFDIHVDEWKRRLIRLLLYHSKQEEKLLKSQRNLVAKMKKVMHL 177
H M +++A YR +Q K LK R + +++ +
Sbjct: 130 HTMRFLEDAAAPYR-----------------------EQIHKCLKCLRK---EREEIQEI 163
Query: 178 QDVEVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTL 237
Q E K ++ ++R ++ +EF+ L FL E++ + L +L ++ + ++ +E L
Sbjct: 164 QSRENKRMQVLLTQVSTKRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDL 223
Query: 238 KLNQTIASLKKLILEVGEKSQAPTLELLQNPKEVLTRSEIQDVNYSL-------EAVKVK 290
+ I LI E+ EK++ P ELL + + L R E + + + ++
Sbjct: 224 LVAGEICRFSALIEELEEKNERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDF 283
Query: 291 TVCQIPLMKEM----------LKRFQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPV 340
+PL +EM L ++L T+HPKL+ S++ + +
Sbjct: 284 PQQALPLQREMKMFLEKLCFELDYEPAHISLDPQTSHPKLLLSEDHQRAQ---------- 333
Query: 341 FSSAWNYFAGWRNPQKTAFVERFQHLPCVLGKNVFTSGKHYW--EVESRDSLEVAVGVCR 398
FS W NPQ RF CVL T G+H W ++ VGV
Sbjct: 334 FSYKWQNSPD--NPQ------RFDRATCVLAHTGITGGRHTWVVSIDLAHGGSCTVGVVS 385
Query: 399 EDVMGITDRSKMSPDVGIWAIYWSAAGYWPLIGFPGTPTQQEPALHRVGVYLDRGTGNVS 458
EDV ++ P+ G+WA+ + L FP T +E +V V LD G V+
Sbjct: 386 EDVQR-KGELRLRPEEGVWAVRLAWGFVSALGSFPTRLTLKEQP-RQVRVSLDYEVGWVT 443
Query: 459 FYSAVDGVHLHTFSCSSVSRLRPFFWL 485
F +AV ++TF+ S ++ PFF L
Sbjct: 444 FTNAVTREPIYTFTASFTRKVIPFFGL 470
>gi|88953346 PREDICTED: Tripartite motif-containing protein 43-like
protein 1 [Homo sapiens]
Length = 446
Score = 196 bits (498), Expect = 4e-50
Identities = 144/487 (29%), Positives = 220/487 (45%), Gaps = 63/487 (12%)
Query: 7 QEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAALRPNWA 66
Q+ELTC ICL+Y DPV+I CGH+FCR CL +W P CP CR PS + N
Sbjct: 10 QKELTCVICLNYLVDPVTICCGHSFCRPCLCLSWEEAQSPANCPACREPSPKMDFKTNIL 69
Query: 67 LARLTEKTQRRRLGPV---PPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHAMAPI 123
L L ++ L +CG H + ++FC+ D+ +CL+C SQEH H PI
Sbjct: 70 LKNLVTIARKASLWQFLSSEKQICGTHRQTKKMFCDMDKSLLCLLCSNSQEHGAHKHYPI 129
Query: 124 DEAFESYRTGNFDIHVDEWKRRLIRLLLYHSKQEEKLLKSQRNLVAKMKKVMHLQDVEVK 183
+EA E R EKLLK R L K+++ E +
Sbjct: 130 EEAAEEDR--------------------------EKLLKQMRILWKKIQENQRNLYEERR 163
Query: 184 NATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTI 243
A + + + I E+ KLH L +EE L+RLNKE +E ++L + +K++Q
Sbjct: 164 TAFLLRGDVVLRAQMIRNEYRKLHPVLHKEEKQHLERLNKEYQEIFQQLQRSWVKMDQKS 223
Query: 244 ASLKKLILEVGEKSQAPTLELLQNPKEVLTRSEIQDVNYSLEAVKVKTVCQIPLMKEMLK 303
LK++ E+ E P +ELLQ+ +++ RSE ++ T I + L
Sbjct: 224 KHLKEMYQELMEMCHKPEVELLQDLGDIVARSESVLLHMPQPVNPELTAGPITGLVYRLN 283
Query: 304 RFQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSW-----PVFSSAWNYFAGWRNPQKTA 358
RF+V ++ + + + ++ R SW P+ S +YFA W
Sbjct: 284 RFRVEISFHFEVTNHNIRLFEDVR---------SWMFRRGPLNSDRSDYFAAW------- 327
Query: 359 FVERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCREDVMGITDRSKMSPDVGIWA 418
G VF+ GKHYWE++ +S + A+GVC + S D+ +
Sbjct: 328 ------------GARVFSFGKHYWELDVDNSCDWALGVCNNSWIRKNSTMVNSEDIFLLL 375
Query: 419 IYWSAAGYWPLIGFPGTPTQQEPALHRVGVYLDRGTGNVSFYSAVDGVHLHTFSCSSVS- 477
+ L P P E L RVGV+LD +G+VSF + + ++ S++
Sbjct: 376 CLKVDNHFNLLTTSPVFPHYIEKPLGRVGVFLDFESGSVSFLNVTKSSLIWSYPAGSLTF 435
Query: 478 RLRPFFW 484
+RPFF+
Sbjct: 436 PVRPFFY 442
>gi|210147600 tripartite motif-containing 64 [Homo sapiens]
Length = 449
Score = 184 bits (468), Expect = 1e-46
Identities = 143/490 (29%), Positives = 218/490 (44%), Gaps = 53/490 (10%)
Query: 1 MEAEDIQ---EELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSA 57
M+++D+Q EL C IC++YF DPV+I+CGH+FCR CL G P CP CR S
Sbjct: 1 MDSDDLQVFQNELICCICVNYFIDPVTIDCGHSFCRPCLCLCSEEGRAPMRCPSCRKISE 60
Query: 58 PAALRPNWALARLTEKTQRRRLGPV--PPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEH 115
N L +L+ ++ R + +C H E LFCE D+R +C C ES EH
Sbjct: 61 KPNFNTNVVLKKLSSLARQTRPQNINSSDNICVLHEETKELFCEADKRLLCGPCSESPEH 120
Query: 116 QTHAMAPIDEAFESYRTGNFDIHVDEWKRRLIRLLLYHSKQEEKLLKSQRNLVAKMKKVM 175
H+ +PI A E R EKL+K L ++
Sbjct: 121 MAHSHSPIGWAAEECR--------------------------EKLIKEMDYLWEINQETR 154
Query: 176 HLQDVEVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNEN 235
+ + E + KD + ++ I+ ++ K+ FL EEE LQ L +E EE ++L ++
Sbjct: 155 NNLNQETRTFHSLKDYVSVRKRIITIQYQKMPIFLDEEEQRHLQALEREAEELFQQLQDS 214
Query: 236 TLKLNQTIASLKKLILEVGEKSQAPTLELLQNPKEVLTRSEIQDVNYSLEAVKVKTVCQI 295
+++ Q + +K + E+ E P +ELLQ+ + V R+++ + T I
Sbjct: 215 QVRMTQHLERMKDMYRELWETCHVPDVELLQDVRNVSARTDLAQMQKPQPVNPELTSWCI 274
Query: 296 PLMKEMLKRFQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQ 355
+ +ML F+V L+ + + S++ RYV S P + FA W
Sbjct: 275 TGVLDMLNNFRVDSALSTEMIPCYISLSEDVRYVIFGDDHLSAPTDPQGVDSFAVW---- 330
Query: 356 KTAFVERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCREDVMGITDRSKMSPDVG 415
G FTSGKHYWEV+ S +GVC +D + D
Sbjct: 331 ---------------GAQAFTSGKHYWEVDVTLSSNWILGVC-QDSRTADANFVIDSDER 374
Query: 416 IWAIYWSAAGYWPL-IGFPGTPTQQEPALHRVGVYLDRGTGNVSFYSAVDGVHLHTFSCS 474
+ I + ++ L P + L +VGV+LD G+VSF+ G ++ F S
Sbjct: 375 FFLISSKRSNHYSLSTNSPPLIQYVQRPLGQVGVFLDYDNGSVSFFDVSKGSLIYGFPPS 434
Query: 475 SVSR-LRPFF 483
S S LRPFF
Sbjct: 435 SFSSPLRPFF 444
>gi|169202375 PREDICTED: tripartite motif-containing protein
64B-like [Homo sapiens]
Length = 449
Score = 184 bits (468), Expect = 1e-46
Identities = 144/490 (29%), Positives = 216/490 (44%), Gaps = 53/490 (10%)
Query: 1 MEAEDIQ---EELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSA 57
M+++D+Q EL C IC++YF DPV+I+CGH+FCR CL G P CP CR S
Sbjct: 1 MDSDDLQVFQNELICCICVNYFIDPVTIDCGHSFCRPCLCLCSEEGRAPMRCPSCRKTSE 60
Query: 58 PAALRPNWALARLTEKTQRRRLGPV--PPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEH 115
N L +L+ ++ R + +C H E LFCE D+R +C C ES EH
Sbjct: 61 KPNFNTNLVLKKLSSLARQTRPQNINSSDNICVLHEETKELFCEADKRLLCGPCSESPEH 120
Query: 116 QTHAMAPIDEAFESYRTGNFDIHVDEWKRRLIRLLLYHSKQEEKLLKSQRNLVAKMKKVM 175
H+ +PI A E R EKL+K L ++
Sbjct: 121 MAHSHSPIGWAAEECR--------------------------EKLIKEMDYLWEINQETR 154
Query: 176 HLQDVEVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNEN 235
+ + E KD + ++ I+ ++ K+ FL EEE LQ L +E EE ++L ++
Sbjct: 155 NNLNQETSTFHSLKDYVSVRKRIITIQYQKMPIFLDEEEQRHLQALEREAEELFQQLQDS 214
Query: 236 TLKLNQTIASLKKLILEVGEKSQAPTLELLQNPKEVLTRSEIQDVNYSLEAVKVKTVCQI 295
+++ Q + +K + E+ E P + LLQ+ + V R+++ + T I
Sbjct: 215 QVRMTQHLERMKDMYRELWETCHMPDVVLLQDVRNVSARTDLAQMQKPQPVNPELTSWCI 274
Query: 296 PLMKEMLKRFQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQ 355
+ +ML F+V L+ + + S++ RYV S P + FA W
Sbjct: 275 TGVLDMLNNFRVDSALSTEMIPCYISLSEDVRYVIFGDDHLSAPTDPQGVDSFAVW---- 330
Query: 356 KTAFVERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCREDVMGITDRSKMSPDVG 415
G FTSGKHYWEV+ S +GVCR D + D
Sbjct: 331 ---------------GAQAFTSGKHYWEVDVTLSSNWILGVCR-DSRTADANFVIDSDER 374
Query: 416 IWAIYWSAAGYWPL-IGFPGTPTQQEPALHRVGVYLDRGTGNVSFYSAVDGVHLHTFSCS 474
+ I + ++ L P + L RVGV+LD G+VSF+ G ++ F S
Sbjct: 375 FFLISSKRSNHYSLSTNSPPLIQYVQRPLGRVGVFLDYDNGSVSFFDVSKGSLIYGFPPS 434
Query: 475 SVSR-LRPFF 483
S S LRPFF
Sbjct: 435 SFSSPLRPFF 444
>gi|14719418 tripartite motif protein TRIM5 isoform alpha [Homo
sapiens]
Length = 493
Score = 184 bits (467), Expect = 2e-46
Identities = 151/517 (29%), Positives = 237/517 (45%), Gaps = 79/517 (15%)
Query: 5 DIQEELTCPICLDYFQDPVSIECGHNFCRGCL---HRNWAPGGGPFPCPECRHPSAPAAL 61
+++EE+TCPICL+ P+S++CGH+FC+ CL H+ G CP CR P +
Sbjct: 8 NVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRISYQPENI 67
Query: 62 RPNWALARLTEKTQRRRLGPVPPGL--CGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHA 119
RPN +A L EK + +L P + C RH E L LFC++D + +C +C SQEH+ H
Sbjct: 68 RPNRHVANLVEKLREVKLSPEGQKVDHCARHGEKLLLFCQEDGKVICWLCERSQEHRGHH 127
Query: 120 MAPIDEAFESYRTGNFDIHVDEWKRRLIRLLLYHSKQEEKLLKSQRNLVAKMKKVMHLQD 179
P +E + Y+ K + +L +QE + L++ D
Sbjct: 128 TFPTEEVAQEYQV----------KLQAALEMLRQKQQEAEELEA---------------D 162
Query: 180 VEVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKL 239
+ + A+ WK +I+ + + +F +L + L EE LQ L KEEE+ K L + ++
Sbjct: 163 IREEKAS-WKTQIQYDKTNVLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEM 221
Query: 240 NQTIASLKKLILEVGEKSQAPTLELLQNPKEVLTRSEIQDVNYSLEAVKV-----KTVCQ 294
Q SL++LI ++ + Q +ELLQ V+ R+E N +L+ + + V +
Sbjct: 222 VQQTQSLRELISDLEHRLQGSVMELLQGVDGVIKRTE----NVTLKKPETFPKNQRRVFR 277
Query: 295 IPLMKEMLKRFQVAVNL----AEDTAHPK----LVFSQEGRYVKNTASASSWPVFSSAWN 346
P +K ML+ F+ ++ + T P V S++ R V S
Sbjct: 278 APDLKGMLEVFRELTDVRRYWVDVTVAPNNISCAVISEDKRQVS-----------SPKPQ 326
Query: 347 YFAGWRNPQKTAFVERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVC---REDVM- 402
G R + FV F + +LG TSGKHYWEV+ +GVC + D M
Sbjct: 327 IIYGARGTRYQTFV-NFNYCTGILGSQSITSGKHYWEVDVSKKTAWILGVCAGFQPDAMC 385
Query: 403 GITDRSKMSPDVGIWAI----------YWSAAGYWPLIGFPGTPTQQEPALHRVGVYLDR 452
I P G W I + ++ + P + F P RVGV+LD
Sbjct: 386 NIEKNENYQPKYGYWVIGLEEGVKCSAFQDSSFHTPSVPFI-VPLSVIICPDRVGVFLDY 444
Query: 453 GTGNVSFYSAVD-GVHLHTFSCSSVSRLRPFF-WLSP 487
VSF++ + G ++ FS S S +P F +L+P
Sbjct: 445 EACTVSFFNITNHGFLIYKFSHCSFS--QPVFPYLNP 479
>gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens]
Length = 488
Score = 182 bits (463), Expect = 5e-46
Identities = 156/531 (29%), Positives = 240/531 (45%), Gaps = 92/531 (17%)
Query: 5 DIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPG----GGPFPCPECRHPSAPAA 60
++QEE+TCPICL+ +P+S++CGH+ CR C+ + GG CP C +
Sbjct: 8 NVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSFEH 67
Query: 61 LRPNWALARLTEKTQRRRLGP---VPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQT 117
L+ N LA + E+ + +L P LC H E L LFC++D++ +C +C SQEH+
Sbjct: 68 LQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCERSQEHRG 127
Query: 118 HAMAPIDEAFESYRTGNFDIHVDEWKRRLIRLLLYHSKQEEKLLKSQRNLVAKMKKVMHL 177
H +E F+ E + +L +L K+EE+ K + ++
Sbjct: 128 HHTVLTEEVFK------------ECQEKLQAVLKRLKKEEEEAEKLEADIR--------- 166
Query: 178 QDVEVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTL 237
+ T WK +++++R RI TEF +L + L EE LQRL +EE++T K E
Sbjct: 167 -----EEKTSWKYQVQTERQRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAED 221
Query: 238 KLNQTIASLKKLILEVGEKSQAPTLELLQNPKEVLTRSEIQDVNY-SLEAVKVKTVCQIP 296
+L Q +++LI +V +SQ T+ELLQ+ ++ SEI + + + K+KTV P
Sbjct: 222 ELVQQKQLVRELISDVECRSQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAP 281
Query: 297 LMKEMLKRFQ---------VAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNY 347
+ ML+ F+ V V L + LV S++ R V S WP +NY
Sbjct: 282 DLSRMLQMFRELTAVRCYWVDVTLNSVNLNLNLVLSEDQRQV---ISVPIWPF--QCYNY 336
Query: 348 FAGWRNPQKTAFVERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGV-CR--EDVMGI 404
VLG F+SGKHYWEV+ +GV CR M
Sbjct: 337 --------------------GVLGSQYFSSGKHYWEVDVSKKTAWILGVYCRTYSRHMKY 376
Query: 405 TDRSKMSPDVGIWAIYWSAAGYWPL-------IGFPGTPTQQEPAL---------HRVGV 448
R + + ++ Y GYW + G +P + RVGV
Sbjct: 377 VVR-RCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEESLSSDPEVLTLSMAVPPCRVGV 435
Query: 449 YLDRGTGNVSFYSAVD-GVHLHTFS-CSSVSRLRPFF--WLSPLASLVIPP 495
+LD G VSF++ G ++ FS C + P+F W P + PP
Sbjct: 436 FLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFNPWNCPAPMTLCPP 486
>gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens]
Length = 488
Score = 182 bits (463), Expect = 5e-46
Identities = 156/531 (29%), Positives = 240/531 (45%), Gaps = 92/531 (17%)
Query: 5 DIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPG----GGPFPCPECRHPSAPAA 60
++QEE+TCPICL+ +P+S++CGH+ CR C+ + GG CP C +
Sbjct: 8 NVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSFEH 67
Query: 61 LRPNWALARLTEKTQRRRLGP---VPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQT 117
L+ N LA + E+ + +L P LC H E L LFC++D++ +C +C SQEH+
Sbjct: 68 LQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCERSQEHRG 127
Query: 118 HAMAPIDEAFESYRTGNFDIHVDEWKRRLIRLLLYHSKQEEKLLKSQRNLVAKMKKVMHL 177
H +E F+ E + +L +L K+EE+ K + ++
Sbjct: 128 HHTVLTEEVFK------------ECQEKLQAVLKRLKKEEEEAEKLEADIR--------- 166
Query: 178 QDVEVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTL 237
+ T WK +++++R RI TEF +L + L EE LQRL +EE++T K E
Sbjct: 167 -----EEKTSWKYQVQTERQRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAED 221
Query: 238 KLNQTIASLKKLILEVGEKSQAPTLELLQNPKEVLTRSEIQDVNY-SLEAVKVKTVCQIP 296
+L Q +++LI +V +SQ T+ELLQ+ ++ SEI + + + K+KTV P
Sbjct: 222 ELVQQKQLVRELISDVECRSQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAP 281
Query: 297 LMKEMLKRFQ---------VAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNY 347
+ ML+ F+ V V L + LV S++ R V S WP +NY
Sbjct: 282 DLSRMLQMFRELTAVRCYWVDVTLNSVNLNLNLVLSEDQRQV---ISVPIWPF--QCYNY 336
Query: 348 FAGWRNPQKTAFVERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGV-CR--EDVMGI 404
VLG F+SGKHYWEV+ +GV CR M
Sbjct: 337 --------------------GVLGSQYFSSGKHYWEVDVSKKTAWILGVYCRTYSRHMKY 376
Query: 405 TDRSKMSPDVGIWAIYWSAAGYWPL-------IGFPGTPTQQEPAL---------HRVGV 448
R + + ++ Y GYW + G +P + RVGV
Sbjct: 377 VVR-RCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEESLSSDPEVLTLSMAVPPCRVGV 435
Query: 449 YLDRGTGNVSFYSAVD-GVHLHTFS-CSSVSRLRPFF--WLSPLASLVIPP 495
+LD G VSF++ G ++ FS C + P+F W P + PP
Sbjct: 436 FLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFNPWNCPAPMTLCPP 486
>gi|51477690 tripartite motif-containing 6 and tripartite
motif-containing 34 [Homo sapiens]
Length = 842
Score = 182 bits (463), Expect = 5e-46
Identities = 156/531 (29%), Positives = 240/531 (45%), Gaps = 92/531 (17%)
Query: 5 DIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPG----GGPFPCPECRHPSAPAA 60
++QEE+TCPICL+ +P+S++CGH+ CR C+ + GG CP C +
Sbjct: 362 NVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCGISYSFEH 421
Query: 61 LRPNWALARLTEKTQRRRLGP---VPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQT 117
L+ N LA + E+ + +L P LC H E L LFC++D++ +C +C SQEH+
Sbjct: 422 LQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCERSQEHRG 481
Query: 118 HAMAPIDEAFESYRTGNFDIHVDEWKRRLIRLLLYHSKQEEKLLKSQRNLVAKMKKVMHL 177
H +E F+ E + +L +L K+EE+ K + ++
Sbjct: 482 HHTVLTEEVFK------------ECQEKLQAVLKRLKKEEEEAEKLEADIR--------- 520
Query: 178 QDVEVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTL 237
+ T WK +++++R RI TEF +L + L EE LQRL +EE++T K E
Sbjct: 521 -----EEKTSWKYQVQTERQRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAED 575
Query: 238 KLNQTIASLKKLILEVGEKSQAPTLELLQNPKEVLTRSEIQDVNY-SLEAVKVKTVCQIP 296
+L Q +++LI +V +SQ T+ELLQ+ ++ SEI + + + K+KTV P
Sbjct: 576 ELVQQKQLVRELISDVECRSQWSTMELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAP 635
Query: 297 LMKEMLKRFQ---------VAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNY 347
+ ML+ F+ V V L + LV S++ R V S WP +NY
Sbjct: 636 DLSRMLQMFRELTAVRCYWVDVTLNSVNLNLNLVLSEDQRQV---ISVPIWPF--QCYNY 690
Query: 348 FAGWRNPQKTAFVERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGV-CR--EDVMGI 404
VLG F+SGKHYWEV+ +GV CR M
Sbjct: 691 --------------------GVLGSQYFSSGKHYWEVDVSKKTAWILGVYCRTYSRHMKY 730
Query: 405 TDRSKMSPDVGIWAIYWSAAGYWPL-------IGFPGTPTQQEPAL---------HRVGV 448
R + + ++ Y GYW + G +P + RVGV
Sbjct: 731 VVR-RCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEESLSSDPEVLTLSMAVPPCRVGV 789
Query: 449 YLDRGTGNVSFYSAVD-GVHLHTFS-CSSVSRLRPFF--WLSPLASLVIPP 495
+LD G VSF++ G ++ FS C + P+F W P + PP
Sbjct: 790 FLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFNPWNCPAPMTLCPP 840
Score = 157 bits (396), Expect = 3e-38
Identities = 97/308 (31%), Positives = 159/308 (51%), Gaps = 36/308 (11%)
Query: 5 DIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPG----GGPFPCPECRHPSAPAA 60
DI+EE+TCPICL+ +P+SI+CGH+FC+ C+ N G CP C+ P
Sbjct: 36 DIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQPGN 95
Query: 61 LRPNWALARLTEKTQRRRLGP---VPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQT 117
LRPN LA + + + LGP + LC H E L+LFC++D + +C +C SQEH+
Sbjct: 96 LRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRG 155
Query: 118 HAMAPIDEAFESYRTGNFDIHVDEWKRRLIRLLLYHSKQEEKLLKSQRNLVAKMKKVMHL 177
H ++E + Y +EK +S + L + ++ L
Sbjct: 156 HHTFLVEEVAQEY--------------------------QEKFQESLKKLKNEEQEAEKL 189
Query: 178 QDVEVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTL 237
+ T WK++++ +R RI TEF++L N L E L++L +EE++ + + E
Sbjct: 190 TAFIREKKTSWKNQMEPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAEN 249
Query: 238 KLNQTIASLKKLILEVGEKSQAPTLELLQNPKEVLTRSEIQDVNYSLEAV--KVKTVCQI 295
L SL++LI ++ + Q T+ELLQ+ +V RSE + EA+ K++++ +
Sbjct: 250 DLVHQTQSLRELISDLERRCQGSTMELLQDVSDVTERSEFWTLR-KPEALPTKLRSMFRA 308
Query: 296 PLMKEMLK 303
P +K ML+
Sbjct: 309 PDLKRMLR 316
>gi|239755488 PREDICTED: similar to ring finger protein 18 isoform 2
[Homo sapiens]
Length = 446
Score = 176 bits (447), Expect = 3e-44
Identities = 131/482 (27%), Positives = 213/482 (44%), Gaps = 53/482 (10%)
Query: 7 QEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAALRPN-- 64
Q EL CPIC++YF DPV+I+CGH+FCR C + NW C EC + L+ N
Sbjct: 10 QRELICPICMNYFIDPVTIDCGHSFCRPCFYLNWKDSPFLVQCSECTKSTGQINLKTNIH 69
Query: 65 -WALARLTEKTQRRRLGPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHAMAPI 123
+A L K +CG H E ++FCE D+ +CL+C SQEH+ H PI
Sbjct: 70 FKKMASLARKVSLWLFLSSEEQMCGTHRETKKMFCEVDRSLLCLLCSSSQEHRDHRHCPI 129
Query: 124 DEAFESYRTGNFDIHVDEWKRRLIRLLLYHSKQEEKLLKSQRNLVAKMKKVMHLQDVEVK 183
+ A E + +EKLL+ ++L K + +VE
Sbjct: 130 ESAAEEH--------------------------QEKLLQKMQSLWEKACENHRNLNVETT 163
Query: 184 NATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTI 243
WKD + + I E+ K+ F EEE L+ L K+ ++ +L+ + K+
Sbjct: 164 RTRCWKDYVNLRLEAIRAEYQKMPAFHHEEEKHNLEMLKKKGKDIFHRLHLSKAKMAHRR 223
Query: 244 ASLKKLILEVGEKSQAPTLELLQNPKEVLTRSEIQDVNYSLEAVKVKTVCQIPLMKEMLK 303
L+ + E+ E P +ELLQ+ +++ RSE ++ T+ I + L
Sbjct: 224 EILRGMYEELNEMCHKPDVELLQDLGDMVARSESVLLHMPQPVNPELTIGPITGPVDRLN 283
Query: 304 RFQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVERF 363
F+V + + + + ++ R + + + S + FA W
Sbjct: 284 HFRVETSFTWEVTNYNIRLFEDVRSLMFRCGSLN----SDRSDNFAAW------------ 327
Query: 364 QHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIYWSA 423
G VF+SGKHYWE++ +S + A+GVC++ + S D+ +
Sbjct: 328 -------GAWVFSSGKHYWELDVDNSWDWALGVCKDSWIRKNSTMVKSKDIFLLLCVKVD 380
Query: 424 AGYWPLIGFPGTPTQQEPALHRVGVYLDRGTGNVSFYSAVDGVHLHTFSCSSVS-RLRPF 482
+ L P P E L RVGV+LD +G+VSF + + ++ S++ +RPF
Sbjct: 381 NHFSLLTTSPMFPDYVEKPLGRVGVFLDFESGSVSFLNVTKSSLIWSYPTGSLNFPVRPF 440
Query: 483 FW 484
F+
Sbjct: 441 FY 442
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.425
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,380,090
Number of Sequences: 37866
Number of extensions: 1080551
Number of successful extensions: 5634
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 251
Number of HSP's successfully gapped in prelim test: 322
Number of HSP's that attempted gapping in prelim test: 4505
Number of HSP's gapped (non-prelim): 973
length of query: 500
length of database: 18,247,518
effective HSP length: 106
effective length of query: 394
effective length of database: 14,233,722
effective search space: 5608086468
effective search space used: 5608086468
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.