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Search of human proteins with 14589935
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14589935 protocadherin 7 isoform c precursor [Homo sapiens]
(1200 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14589935 protocadherin 7 isoform c precursor [Homo sapiens] 2393 0.0
gi|14589933 protocadherin 7 isoform b precursor [Homo sapiens] 1987 0.0
gi|14589931 protocadherin 7 isoform a precursor [Homo sapiens] 1987 0.0
gi|27754773 protocadherin 1 isoform 2 precursor [Homo sapiens] 1093 0.0
gi|27754771 protocadherin 1 isoform 1 precursor [Homo sapiens] 903 0.0
gi|9966883 protocadherin 9 isoform 2 precursor [Homo sapiens] 709 0.0
gi|45243534 protocadherin 9 isoform 1 precursor [Homo sapiens] 697 0.0
gi|14589946 protocadherin 11 Y-linked isoform c [Homo sapiens] 615 e-175
gi|14589922 protocadherin 11 X-linked isoform d [Homo sapiens] 605 e-172
gi|14589920 protocadherin 11 X-linked isoform c [Homo sapiens] 600 e-171
gi|14589918 protocadherin 11 X-linked isoform b precursor [Homo ... 586 e-167
gi|14589944 protocadherin 11 Y-linked isoform b [Homo sapiens] 583 e-166
gi|14589942 protocadherin 11 Y-linked isoform a [Homo sapiens] 583 e-166
gi|7657443 protocadherin 11 X-linked isoform a precursor [Homo s... 580 e-165
gi|190194360 protocadherin 20 [Homo sapiens] 369 e-102
gi|14589916 protocadherin 10 isoform 1 precursor [Homo sapiens] 309 9e-84
gi|14589914 protocadherin 10 isoform 2 precursor [Homo sapiens] 309 9e-84
gi|14270505 protocadherin gamma subfamily B, 5 isoform 2 precurs... 296 8e-80
gi|11128031 protocadherin gamma subfamily B, 5 isoform 1 precurs... 296 8e-80
gi|14277685 protocadherin gamma subfamily C, 5 isoform 2 precurs... 288 3e-77
gi|11128023 protocadherin gamma subfamily C, 5 isoform 1 precurs... 288 3e-77
gi|14270499 protocadherin gamma subfamily B, 4 isoform 2 precurs... 285 2e-76
gi|13470082 protocadherin gamma subfamily B, 4 isoform 1 precurs... 285 2e-76
gi|11036656 protocadherin beta 7 precursor [Homo sapiens] 281 2e-75
gi|14270508 protocadherin gamma subfamily B, 7 isoform 2 precurs... 281 3e-75
gi|11128027 protocadherin gamma subfamily B, 7 isoform 1 precurs... 281 3e-75
gi|11128029 protocadherin gamma subfamily B, 6 isoform 1 precurs... 280 6e-75
gi|14270502 protocadherin gamma subfamily B, 6 isoform 2 precurs... 280 6e-75
gi|9256602 protocadherin beta 10 precursor [Homo sapiens] 279 1e-74
gi|14195616 protocadherin beta 9 precursor [Homo sapiens] 277 5e-74
>gi|14589935 protocadherin 7 isoform c precursor [Homo sapiens]
Length = 1200
Score = 2393 bits (6202), Expect = 0.0
Identities = 1200/1200 (100%), Positives = 1200/1200 (100%)
Query: 1 MLRMRTAGWARGWCLGCCLLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGIVTG 60
MLRMRTAGWARGWCLGCCLLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGIVTG
Sbjct: 1 MLRMRTAGWARGWCLGCCLLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGIVTG 60
Query: 61 SGEVTFSLESGSEYLKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPS 120
SGEVTFSLESGSEYLKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPS
Sbjct: 61 SGEVTFSLESGSEYLKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPS 120
Query: 121 QSWVDLFEGQVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERY 180
QSWVDLFEGQVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERY
Sbjct: 121 QSWVDLFEGQVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERY 180
Query: 181 ELLQEPGGGGSGGESRRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGR 240
ELLQEPGGGGSGGESRRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGR
Sbjct: 181 ELLQEPGGGGSGGESRRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGR 240
Query: 241 SSVFELQVADTPDGEKQPQLIVKGVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVF 300
SSVFELQVADTPDGEKQPQLIVKGVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVF
Sbjct: 241 SSVFELQVADTPDGEKQPQLIVKGVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVF 300
Query: 301 GAATESVRRLLRLDETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKD 360
GAATESVRRLLRLDETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKD
Sbjct: 301 GAATESVRRLLRLDETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKD 360
Query: 361 ENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVP 420
ENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVP
Sbjct: 361 ENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVP 420
Query: 421 FQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGD 480
FQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGD
Sbjct: 421 FQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGD 480
Query: 481 TNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPD 540
TNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPD
Sbjct: 481 TNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPD 540
Query: 541 SGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFY 600
SGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFY
Sbjct: 541 SGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFY 600
Query: 601 VKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTT 660
VKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTT
Sbjct: 601 VKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTT 660
Query: 661 YTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSNVRTVVATVL 720
YTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSNVRTVVATVL
Sbjct: 661 YTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSNVRTVVATVL 720
Query: 721 ATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQP 780
ATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQP
Sbjct: 721 ATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQP 780
Query: 781 SQSTTTLVHVFVNESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAG 840
SQSTTTLVHVFVNESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAG
Sbjct: 781 SQSTTTLVHVFVNESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAG 840
Query: 841 IMTVILIILIVVMARYCRSKNKNGYEAGKKDHEDFFTPQQHDKSKKPKKDKKNKKSKQPL 900
IMTVILIILIVVMARYCRSKNKNGYEAGKKDHEDFFTPQQHDKSKKPKKDKKNKKSKQPL
Sbjct: 841 IMTVILIILIVVMARYCRSKNKNGYEAGKKDHEDFFTPQQHDKSKKPKKDKKNKKSKQPL 900
Query: 901 YSSIVTVEASKPNGQRYDSVNEKLSDSPSMGRYRSVNGGPGSPDLARHYKSSSPLPTVQL 960
YSSIVTVEASKPNGQRYDSVNEKLSDSPSMGRYRSVNGGPGSPDLARHYKSSSPLPTVQL
Sbjct: 901 YSSIVTVEASKPNGQRYDSVNEKLSDSPSMGRYRSVNGGPGSPDLARHYKSSSPLPTVQL 960
Query: 961 HPQSPTAGKKHQAVQDLPPANTFVGAGDNISIGSDHCSEYSCQTNNKYSKQPFRRVTFSV 1020
HPQSPTAGKKHQAVQDLPPANTFVGAGDNISIGSDHCSEYSCQTNNKYSKQPFRRVTFSV
Sbjct: 961 HPQSPTAGKKHQAVQDLPPANTFVGAGDNISIGSDHCSEYSCQTNNKYSKQPFRRVTFSV 1020
Query: 1021 VSQPQDPHQGSLQSCYDSGLEESETPSSKSSSGPRLGALPLPEDNYERTTPDGSVDSRPL 1080
VSQPQDPHQGSLQSCYDSGLEESETPSSKSSSGPRLGALPLPEDNYERTTPDGSVDSRPL
Sbjct: 1021 VSQPQDPHQGSLQSCYDSGLEESETPSSKSSSGPRLGALPLPEDNYERTTPDGSVDSRPL 1080
Query: 1081 PDVALTGKCTRECDEYGHSDSCWMPVRTSPERKKSQPKLSTFMPVDERGSQEKLANGEAA 1140
PDVALTGKCTRECDEYGHSDSCWMPVRTSPERKKSQPKLSTFMPVDERGSQEKLANGEAA
Sbjct: 1081 PDVALTGKCTRECDEYGHSDSCWMPVRTSPERKKSQPKLSTFMPVDERGSQEKLANGEAA 1140
Query: 1141 IMGDRNRNLLNKKLTSSYETFSAASFSKNEEANPEDIPLTKTGEYKPSPVNTLTRREVYL 1200
IMGDRNRNLLNKKLTSSYETFSAASFSKNEEANPEDIPLTKTGEYKPSPVNTLTRREVYL
Sbjct: 1141 IMGDRNRNLLNKKLTSSYETFSAASFSKNEEANPEDIPLTKTGEYKPSPVNTLTRREVYL 1200
>gi|14589933 protocadherin 7 isoform b precursor [Homo sapiens]
Length = 1072
Score = 1987 bits (5147), Expect = 0.0
Identities = 1011/1058 (95%), Positives = 1011/1058 (95%), Gaps = 47/1058 (4%)
Query: 1 MLRMRTAGWARGWCLGCCLLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGIVTG 60
MLRMRTAGWARGWCLGCCLLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGIVTG
Sbjct: 1 MLRMRTAGWARGWCLGCCLLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGIVTG 60
Query: 61 SGEVTFSLESGSEYLKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPS 120
SGEVTFSLESGSEYLKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPS
Sbjct: 61 SGEVTFSLESGSEYLKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPS 120
Query: 121 QSWVDLFEGQVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERY 180
QSWVDLFEGQVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERY
Sbjct: 121 QSWVDLFEGQVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERY 180
Query: 181 ELLQEPGGGGSGGESRRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGR 240
ELLQEPGGGGSGGESRRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGR
Sbjct: 181 ELLQEPGGGGSGGESRRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGR 240
Query: 241 SSVFELQVADTPDGEKQPQLIVKG------------------------------------ 264
SSVFELQVADTPDGEKQPQLIVKG
Sbjct: 241 SSVFELQVADTPDGEKQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITD 300
Query: 265 -----------VYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRL 313
VYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRL
Sbjct: 301 VNDNSPRFEKSVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRL 360
Query: 314 DETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKI 373
DETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKI
Sbjct: 361 DETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKI 420
Query: 374 GRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQ 433
GRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQ
Sbjct: 421 GRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQ 480
Query: 434 NKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVV 493
NKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVV
Sbjct: 481 NKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVV 540
Query: 494 EVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDRE 553
EVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDRE
Sbjct: 541 EVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDRE 600
Query: 554 QTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGM 613
QTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGM
Sbjct: 601 QTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGM 660
Query: 614 VTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDP 673
VTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDP
Sbjct: 661 VTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDP 720
Query: 674 PRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLN 733
PRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLN
Sbjct: 721 PRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLN 780
Query: 734 YSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVN 793
YSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVN
Sbjct: 781 YSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVN 840
Query: 794 ESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVM 853
ESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVM
Sbjct: 841 ESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVM 900
Query: 854 ARYCRSKNKNGYEAGKKDHEDFFTPQQHDKSKKPKKDKKNKKSKQPLYSSIVTVEASKPN 913
ARYCRSKNKNGYEAGKKDHEDFFTPQQHDKSKKPKKDKKNKKSKQPLYSSIVTVEASKPN
Sbjct: 901 ARYCRSKNKNGYEAGKKDHEDFFTPQQHDKSKKPKKDKKNKKSKQPLYSSIVTVEASKPN 960
Query: 914 GQRYDSVNEKLSDSPSMGRYRSVNGGPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQA 973
GQRYDSVNEKLSDSPSMGRYRSVNGGPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQA
Sbjct: 961 GQRYDSVNEKLSDSPSMGRYRSVNGGPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQA 1020
Query: 974 VQDLPPANTFVGAGDNISIGSDHCSEYSCQTNNKYSKQ 1011
VQDLPPANTFVGAGDNISIGSDHCSEYSCQTNNKYSKQ
Sbjct: 1021 VQDLPPANTFVGAGDNISIGSDHCSEYSCQTNNKYSKQ 1058
>gi|14589931 protocadherin 7 isoform a precursor [Homo sapiens]
Length = 1069
Score = 1987 bits (5147), Expect = 0.0
Identities = 1011/1058 (95%), Positives = 1011/1058 (95%), Gaps = 47/1058 (4%)
Query: 1 MLRMRTAGWARGWCLGCCLLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGIVTG 60
MLRMRTAGWARGWCLGCCLLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGIVTG
Sbjct: 1 MLRMRTAGWARGWCLGCCLLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGIVTG 60
Query: 61 SGEVTFSLESGSEYLKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPS 120
SGEVTFSLESGSEYLKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPS
Sbjct: 61 SGEVTFSLESGSEYLKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPS 120
Query: 121 QSWVDLFEGQVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERY 180
QSWVDLFEGQVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERY
Sbjct: 121 QSWVDLFEGQVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERY 180
Query: 181 ELLQEPGGGGSGGESRRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGR 240
ELLQEPGGGGSGGESRRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGR
Sbjct: 181 ELLQEPGGGGSGGESRRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGR 240
Query: 241 SSVFELQVADTPDGEKQPQLIVKG------------------------------------ 264
SSVFELQVADTPDGEKQPQLIVKG
Sbjct: 241 SSVFELQVADTPDGEKQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITD 300
Query: 265 -----------VYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRL 313
VYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRL
Sbjct: 301 VNDNSPRFEKSVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRL 360
Query: 314 DETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKI 373
DETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKI
Sbjct: 361 DETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKI 420
Query: 374 GRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQ 433
GRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQ
Sbjct: 421 GRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQ 480
Query: 434 NKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVV 493
NKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVV
Sbjct: 481 NKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVV 540
Query: 494 EVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDRE 553
EVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDRE
Sbjct: 541 EVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDRE 600
Query: 554 QTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGM 613
QTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGM
Sbjct: 601 QTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGM 660
Query: 614 VTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDP 673
VTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDP
Sbjct: 661 VTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDP 720
Query: 674 PRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLN 733
PRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLN
Sbjct: 721 PRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLN 780
Query: 734 YSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVN 793
YSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVN
Sbjct: 781 YSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVN 840
Query: 794 ESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVM 853
ESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVM
Sbjct: 841 ESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVM 900
Query: 854 ARYCRSKNKNGYEAGKKDHEDFFTPQQHDKSKKPKKDKKNKKSKQPLYSSIVTVEASKPN 913
ARYCRSKNKNGYEAGKKDHEDFFTPQQHDKSKKPKKDKKNKKSKQPLYSSIVTVEASKPN
Sbjct: 901 ARYCRSKNKNGYEAGKKDHEDFFTPQQHDKSKKPKKDKKNKKSKQPLYSSIVTVEASKPN 960
Query: 914 GQRYDSVNEKLSDSPSMGRYRSVNGGPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQA 973
GQRYDSVNEKLSDSPSMGRYRSVNGGPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQA
Sbjct: 961 GQRYDSVNEKLSDSPSMGRYRSVNGGPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQA 1020
Query: 974 VQDLPPANTFVGAGDNISIGSDHCSEYSCQTNNKYSKQ 1011
VQDLPPANTFVGAGDNISIGSDHCSEYSCQTNNKYSKQ
Sbjct: 1021 VQDLPPANTFVGAGDNISIGSDHCSEYSCQTNNKYSKQ 1058
>gi|27754773 protocadherin 1 isoform 2 precursor [Homo sapiens]
Length = 1237
Score = 1093 bits (2827), Expect = 0.0
Identities = 605/1209 (50%), Positives = 804/1209 (66%), Gaps = 44/1209 (3%)
Query: 19 LLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGIVTGSGEVTFSLESGSEYLKID 78
LLL L+ S A +++ Y++ EE P + IG++A+D G G + + LE G+ YL++D
Sbjct: 46 LLLLLAPSPGHATRVV-YKVPEEQPPNTLIGSLAADYGF-PDVGHL-YKLEVGAPYLRVD 102
Query: 79 NLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVD-LFEGQVIVLDIN 137
TG++ T+E IDRE L +CQ + C L+FEVS+ Q+ L EGQ+ V DIN
Sbjct: 103 GKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQNGSPRLLEGQIEVQDIN 162
Query: 138 DNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRR 197
DNTP F SPV+TL + EN +G+L+ +P A+DRD G NG+ YEL P G
Sbjct: 163 DNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQELFGLQVA 222
Query: 198 AGAADSAPYPGGGGNGASGGGSGGSKRRLDASE-----GGGGTNPGGRSSVFELQVADTP 252
+ P GN + R D+ + GG+ P S++ + V DT
Sbjct: 223 EDQEEKQPQLIVMGN--------LDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTN 274
Query: 253 DGEKQPQLIVKGVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLR 312
D + + YEA+L+ENS G ++Q++A D D G N +IEY F A E VRRLLR
Sbjct: 275 DNAPK---FERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLLR 331
Query: 313 LDETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRK 372
LD +G ++V +DRE+++ LRF+V+A+DRG PK+ +A VV+ +KD NDN P+IEIR
Sbjct: 332 LDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRG 391
Query: 373 IGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGD 432
IG + +DG+AN++EDV +T +ALVQVSDRD+GEN VTC V GDVPFQL+ AS+T G
Sbjct: 392 IGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASET-GS 450
Query: 433 QNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSV 492
+KKKYFL T+TPLDYE +++ + IVAVDSG+P LSS NSL V+V D NDN P+F QSV
Sbjct: 451 DSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSV 510
Query: 493 VEVYFPENNIPGERVATVLATDADSGKNAEIAYSL--DSSVMGIFAIDPDSGDILVNTVL 550
EV FPENN PGE +A + A+DADSG NAE+ YSL + + G+F I P++G+I V T L
Sbjct: 511 TEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSL 570
Query: 551 DREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSP 610
DREQ + YE KV A D+G P LQG+ TV+V V D NDNDPKFM + F V EN+ SP
Sbjct: 571 DREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSP 630
Query: 611 VGMVTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDG 670
VGMVTV+D DKG NA++ L +E++N F I+N TGTI S++SFDRE Q+TYTF++KAVDG
Sbjct: 631 VGMVTVIDGDKGENAQVQLSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDG 690
Query: 671 GDPPRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINA 730
G PPRSA V++ V+DENDNAP +T P N S+ LL P + + V+ V A D D G+NA
Sbjct: 691 GVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKLLTPQTRLGETVSQVAAEDFDSGVNA 750
Query: 731 DLNYSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHV 790
+L YSI GGNP+ LF+I SG ++L ++ ++H+GLHRLVV+V+D G+P + T LVH+
Sbjct: 751 ELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHL 810
Query: 791 FVNESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILI 850
+VNE+++N T +++ + SL PL DIAGDP YE SKQR +I+ GVVAG++ V L+I +
Sbjct: 811 YVNETLANRTLLETLLGHSLDTPLDIDIAGDPEYERSKQRGNILFGVVAGVVAVALLIAL 870
Query: 851 VVMARYCRSKN-KNGYEAGKKDHEDFFTPQQHDKSKKPKKDK-KNKKSKQPLYSSIVTVE 908
V+ RYCR + K+GY+AGKK+ +D + P+ K+ K K K K KS +P+ E
Sbjct: 871 AVLVRYCRQREAKSGYQAGKKETKDLYAPKPSGKASKGNKSKGKKSKSPKPVKPVEDEDE 930
Query: 909 ASKPNGQRYDSVNEKLSDSPSMGRYRSVNGGPGSPDLARHYKSSSPLPTVQLHPQSPTAG 968
A +++ +++ DSP + + +N PGSPDL RHY+S+SPLP++QL PQSP+A
Sbjct: 931 AGLQKSLKFNLMSDAPGDSPRI--HLPLNYPPGSPDLGRHYRSNSPLPSIQLQPQSPSAS 988
Query: 969 KKHQAVQDLPPANTFVGAGDNISIGSDHCSEYSCQTN-NKY-SKQ-PFRRVTFSVVSQPQ 1025
KKHQ VQDLPPANTFVG GD S GS+ S+YS +TN KY SKQ P RRVTFS SQ Q
Sbjct: 989 KKHQVVQDLPPANTFVGTGDTTSTGSEQYSDYSYRTNPPKYPSKQLPHRRVTFSATSQAQ 1048
Query: 1026 DPHQGSLQSCYDSGLEESETPSSKSSSGPRLGALPLPEDNYERTTPDGSV--------DS 1077
+ S S YDSGLEESETPSSKSSSGPRLG L LPED+YERTTPDGS+ D
Sbjct: 1049 ELQDPSQHSYYDSGLEESETPSSKSSSGPRLGPLALPEDHYERTTPDGSIGEMEHPENDL 1108
Query: 1078 RPLPDVALTGKCTRECDEYGHSDSCWMPVRTSPER--KKSQPKLSTFMPVDERGSQEKLA 1135
RPLPDVA+TG CTREC E+GHSD+CWMP ++SP R K S KLSTF+P +RG QE
Sbjct: 1109 RPLPDVAMTGTCTRECSEFGHSDTCWMPGQSSPSRRTKSSALKLSTFVPYQDRGGQEPAG 1168
Query: 1136 NGEAAIMGDRNRNLLNKKLTSSYETFSAASF-SKNEEANPEDIPLTKTGEYKP--SPVNT 1192
G + DRN +L SY FS +S S + A E+IPLT+T ++ P +P +
Sbjct: 1169 AGSPSPPEDRNTKTAPVRLLPSYSAFSHSSHDSCKDSATLEEIPLTQTSDFPPAATPASA 1228
Query: 1193 LT-RREVYL 1200
T +RE+YL
Sbjct: 1229 QTAKREIYL 1237
>gi|27754771 protocadherin 1 isoform 1 precursor [Homo sapiens]
Length = 1060
Score = 903 bits (2333), Expect = 0.0
Identities = 494/1021 (48%), Positives = 674/1021 (66%), Gaps = 32/1021 (3%)
Query: 19 LLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGIVTGSGEVTFSLESGSEYLKID 78
LLL L+ S A +++ Y++ EE P + IG++A+D G G + + LE G+ YL++D
Sbjct: 46 LLLLLAPSPGHATRVV-YKVPEEQPPNTLIGSLAADYGF-PDVGHL-YKLEVGAPYLRVD 102
Query: 79 NLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVD-LFEGQVIVLDIN 137
TG++ T+E IDRE L +CQ + C L+FEVS+ Q+ L EGQ+ V DIN
Sbjct: 103 GKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQNGSPRLLEGQIEVQDIN 162
Query: 138 DNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRR 197
DNTP F SPV+TL + EN +G+L+ +P A+DRD G NG+ YEL P G
Sbjct: 163 DNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQELFGLQVA 222
Query: 198 AGAADSAPYPGGGGNGASGGGSGGSKRRLDASE-----GGGGTNPGGRSSVFELQVADTP 252
+ P GN + R D+ + GG+ P S++ + V DT
Sbjct: 223 EDQEEKQPQLIVMGN--------LDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTN 274
Query: 253 DGEKQPQLIVKGVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLR 312
D + + YEA+L+ENS G ++Q++A D D G N +IEY F A E VRRLLR
Sbjct: 275 DNAPK---FERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLLR 331
Query: 313 LDETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRK 372
LD +G ++V +DRE+++ LRF+V+A+DRG PK+ +A VV+ +KD NDN P+IEIR
Sbjct: 332 LDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRG 391
Query: 373 IGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGD 432
IG + +DG+AN++EDV +T +ALVQVSDRD+GEN VTC V GDVPFQL+ AS+T G
Sbjct: 392 IGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASET-GS 450
Query: 433 QNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSV 492
+KKKYFL T+TPLDYE +++ + IVAVDSG+P LSS NSL V+V D NDN P+F QSV
Sbjct: 451 DSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSV 510
Query: 493 VEVYFPENNIPGERVATVLATDADSGKNAEIAYSL--DSSVMGIFAIDPDSGDILVNTVL 550
EV FPENN PGE +A + A+DADSG NAE+ YSL + + G+F I P++G+I V T L
Sbjct: 511 TEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSL 570
Query: 551 DREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSP 610
DREQ + YE KV A D+G P LQG+ TV+V V D NDNDPKFM + F V EN+ SP
Sbjct: 571 DREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSP 630
Query: 611 VGMVTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDG 670
VGMVTV+D DKG NA++ L +E++N F I+N TGTI S++SFDRE Q+TYTF++KAVDG
Sbjct: 631 VGMVTVIDGDKGENAQVQLSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDG 690
Query: 671 GDPPRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINA 730
G PPRSA V++ V+DENDNAP +T P N S+ LL P + + V+ V A D D G+NA
Sbjct: 691 GVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKLLTPQTRLGETVSQVAAEDFDSGVNA 750
Query: 731 DLNYSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHV 790
+L YSI GGNP+ LF+I SG ++L ++ ++H+GLHRLVV+V+D G+P + T LVH+
Sbjct: 751 ELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHL 810
Query: 791 FVNESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILI 850
+VNE+++N T +++ + SL PL DIAGDP YE SKQR +I+ GVVAG++ V L+I +
Sbjct: 811 YVNETLANRTLLETLLGHSLDTPLDIDIAGDPEYERSKQRGNILFGVVAGVVAVALLIAL 870
Query: 851 VVMARYCRSKN-KNGYEAGKKDHEDFFTPQQHDKSKKPKKDK-KNKKSKQPLYSSIVTVE 908
V+ RYCR + K+GY+AGKK+ +D + P+ K+ K K K K KS +P+ E
Sbjct: 871 AVLVRYCRQREAKSGYQAGKKETKDLYAPKPSGKASKGNKSKGKKSKSPKPVKPVEDEDE 930
Query: 909 ASKPNGQRYDSVNEKLSDSPSMGRYRSVNGGPGSPDLARHYKSSSPLPTVQLHPQSPTAG 968
A +++ +++ DSP + + +N PGSPDL RHY+S+SPLP++QL PQSP+A
Sbjct: 931 AGLQKSLKFNLMSDAPGDSPRI--HLPLNYPPGSPDLGRHYRSNSPLPSIQLQPQSPSAS 988
Query: 969 KKHQAVQDLPPANTFVGAGDNISIGSDHCSEYSCQTN-----NKYSKQPFRRVTFSVVSQ 1023
KKHQ VQDLPPANTFVG GD S GS+ S+YS +TN +K QPF+ T +
Sbjct: 989 KKHQVVQDLPPANTFVGTGDTTSTGSEQYSDYSYRTNPPKYPSKQVGQPFQLSTPQPLPH 1048
Query: 1024 P 1024
P
Sbjct: 1049 P 1049
>gi|9966883 protocadherin 9 isoform 2 precursor [Homo sapiens]
Length = 1203
Score = 709 bits (1831), Expect = 0.0
Identities = 466/1240 (37%), Positives = 667/1240 (53%), Gaps = 96/1240 (7%)
Query: 11 RGWCLGCCLLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGI-----VTG-SGEV 64
R + L L+ L L A A++L+ Y + EE P +V IGN+ DL I TG S +
Sbjct: 4 RDFYLLAALIACLRLDSAIAQELI-YTIREELPENVPIGNIPKDLNISHINAATGTSASL 62
Query: 65 TFSLES---GSEYLKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQ 121
+ L S + +K+ + TGE+ T+ RIDREKL +ENECF + EV ++
Sbjct: 63 VYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVIL--PN 120
Query: 122 SWVDLFEGQVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYE 181
+ L + ++IV D NDN P FPSPV+ +++ EN + + + +P+ATD D G NG++ YE
Sbjct: 121 DFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYE 180
Query: 182 LLQEPGGGGSGGESRRAGAADSAPYPGGGGNGASGGGSGGSKRRLDA-----SEGGGGTN 236
LL G+S D P G + + D GGT
Sbjct: 181 LLN--------GQS--VFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTP 230
Query: 237 PGGRSSVFELQVADTPDGEKQPQLIVKGVYEADLAENSAPGTPILQLRAADLDVGVNGQI 296
+++ ++ V+D D + +G E + EN+ GT ++QL A D D+G N +I
Sbjct: 231 QKSSTAILQVTVSDVNDNRP---VFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEI 287
Query: 297 EYVFGA-ATESVRRLLRLDETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVV 355
Y+FGA + +RL L+ T+G ++V +DREE + TV+A D P +ATV
Sbjct: 288 RYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPA--RATVT 345
Query: 356 LNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTV 415
+N+ D NDN P+I++R I I +G ++E V+T IAL+ VSD+D NG V C +
Sbjct: 346 INVTDVNDNPPNIDLRYI--ISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFI 403
Query: 416 VGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLI 475
+VPF LK D + Y L TS+ LDYE T+EF+ IVA DSG PSL+ +
Sbjct: 404 EREVPFHLKAVYDNQ-------YLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVR 456
Query: 476 VKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIF 535
VK+ D NDNPP+F Q V+E+ ENN G + T+ ATD DSGKNA+I Y L + F
Sbjct: 457 VKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQLGPNA-SFF 515
Query: 536 AIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQD 595
+D +G + + V DRE+ +R+ F V A+D G P LQ VIV V D+NDN PKF +
Sbjct: 516 DLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHN 575
Query: 596 VFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDR 655
F F+V ENL S VG++TV DAD G N ++L I +N+ F ++ +G I S +SFDR
Sbjct: 576 HFQFFVSENLPKYSTVGVITVTDADAGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDR 635
Query: 656 EHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTV-TLPKNISYTLLPPSSNVRT 714
E Q++YTF VKA DGG PPRS+TA V++ VMD NDN+P V + P N S+ L+P S+ +
Sbjct: 636 EQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGS 695
Query: 715 VVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQV 774
VVA V A D D G+NA+L Y+IV GN LF IDP +G ++L K GLHRLVV +
Sbjct: 696 VVAEVFAVDVDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNI 755
Query: 775 NDSGQP-SQSTTTLVHVFVNESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSI 833
+D G P S T LV ++VN++ NA+ I I R++ PL ++I ++ L+I
Sbjct: 756 SDLGYPKSLHTLVLVFLYVNDTAGNASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTI 815
Query: 834 VIGVVAGIMTVILIILIVVMARYCRSKNKNGYEAGKKDHEDFFTPQQHDKSKKPKKDKKN 893
+I ++AG M VI++I + V+ R CR ++ K ++ +P Q +K K KK KK
Sbjct: 816 MIAIIAGAMVVIVVIFVTVLVR-CRHASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKKR 874
Query: 894 KKSKQPLYSSIVTVEASKPNGQRYDSVNEKLS-----DSPSMGRY-----RSVNGGPGSP 943
K K L + VT+E SKP+ ++ +N +S + S+GR+ P SP
Sbjct: 875 KSPKSSLL-NFVTIEESKPDDAVHEPINGTISLPAELEEQSIGRFDWGPAPPTTFKPNSP 933
Query: 944 DLARHYKSSSPLPTVQLHPQSPTAGKKHQAVQDLPPANTFVGAGDNI----SIGSDHCSE 999
DLA+HYKS+SP P L P +P + KKH +Q+LP NTFVG D + S SDH S
Sbjct: 934 DLAKHYKSASPQPAFHLKPDTPVSVKKHHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSA 993
Query: 1000 YSCQTNNKY-------SKQPFRRVTFSVVSQPQDPHQGSLQSCYDSGLEESETPSSKSSS 1052
C + + ++Q RRVTF + GS +SC DSGL + E S +
Sbjct: 994 SECSSQGGFKTKGPLHTRQSQRRVTFHL-------PDGSQESCSDSGLGDHEPVGSGTLI 1046
Query: 1053 GPRLGALPLPEDNYERTTPDGSVD----SRPLPDVAL--------TGKCTRECDEYGHSD 1100
L + ++ Y++ +PD + S P D L T CT+EC GHSD
Sbjct: 1047 SHPLPLVQPQDEFYDQASPDKRTEADGNSDPNSDGPLGPRGLAEATEMCTQECLVLGHSD 1106
Query: 1101 SCWMPVRTSPERKKSQPKLSTFMPVDERGSQEKLANGEA---AIMGDRNRNLLNKKLTSS 1157
+CWMP P + P LSTF P E ++KL NG A D NRN N +
Sbjct: 1107 NCWMPPGLGPYQHPKSP-LSTFAPQKEWVKKDKLVNGHTLTRAWKEDSNRNQFNDR---- 1161
Query: 1158 YETFSAASFSKNEEANPEDIPLTKTGEYKPSPVNTLTRRE 1197
+ + + N ++ DIPL YK + T + +E
Sbjct: 1162 -KQYGSNEGHFNNGSHMTDIPLANLKSYKQAGGATESPKE 1200
>gi|45243534 protocadherin 9 isoform 1 precursor [Homo sapiens]
Length = 1237
Score = 697 bits (1798), Expect = 0.0
Identities = 466/1267 (36%), Positives = 668/1267 (52%), Gaps = 116/1267 (9%)
Query: 11 RGWCLGCCLLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGI-----VTG-SGEV 64
R + L L+ L L A A++L+ Y + EE P +V IGN+ DL I TG S +
Sbjct: 4 RDFYLLAALIACLRLDSAIAQELI-YTIREELPENVPIGNIPKDLNISHINAATGTSASL 62
Query: 65 TFSLES---GSEYLKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQ 121
+ L S + +K+ + TGE+ T+ RIDREKL +ENECF + EV ++
Sbjct: 63 VYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVIL--PN 120
Query: 122 SWVDLFEGQVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYE 181
+ L + ++IV D NDN P FPSPV+ +++ EN + + + +P+ATD D G NG++ YE
Sbjct: 121 DFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYE 180
Query: 182 LLQEPGGGGSGGESRRAGAADSAPYPGGGGNGASGGGSGGSKRRLDA-----SEGGGGTN 236
LL G+S D P G + + D GGT
Sbjct: 181 LLN--------GQS--VFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTP 230
Query: 237 PGGRSSVFELQVADTPDGEKQPQLIVKGVYEADLAENSAPGTPILQLRAADLDVGVNGQI 296
+++ ++ V+D D + +G E + EN+ GT ++QL A D D+G N +I
Sbjct: 231 QKSSTAILQVTVSDVNDNRP---VFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEI 287
Query: 297 EYVFGA-ATESVRRLLRLDETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVV 355
Y+FGA + +RL L+ T+G ++V +DREE + TV+A D P +ATV
Sbjct: 288 RYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPA--RATVT 345
Query: 356 LNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTV 415
+N+ D NDN P+I++R I I +G ++E V+T IAL+ VSD+D NG V C +
Sbjct: 346 INVTDVNDNPPNIDLRYI--ISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFI 403
Query: 416 VGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLI 475
+VPF LK D + Y L TS+ LDYE T+EF+ IVA DSG PSL+ +
Sbjct: 404 EREVPFHLKAVYDNQ-------YLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVR 456
Query: 476 VKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIF 535
VK+ D NDNPP+F Q V+E+ ENN G + T+ ATD DSGKNA+I Y L + F
Sbjct: 457 VKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQLGPNA-SFF 515
Query: 536 AIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQD 595
+D +G + + V DRE+ +R+ F V A+D G P LQ VIV V D+NDN PKF +
Sbjct: 516 DLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHN 575
Query: 596 VFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDR 655
F F+V ENL S VG++TV DAD G N ++L I +N+ F ++ +G I S +SFDR
Sbjct: 576 HFQFFVSENLPKYSTVGVITVTDADAGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDR 635
Query: 656 EHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTV-TLPKNISYTLLPPSSNVRT 714
E Q++YTF VKA DGG PPRS+TA V++ VMD NDN+P V + P N S+ L+P S+ +
Sbjct: 636 EQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGS 695
Query: 715 VVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQV 774
VVA V A D D G+NA+L Y+IV GN LF IDP +G ++L K GLHRLVV +
Sbjct: 696 VVAEVFAVDVDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNI 755
Query: 775 NDSGQP-SQSTTTLVHVFVNESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSI 833
+D G P S T LV ++VN++ NA+ I I R++ PL ++I ++ L+I
Sbjct: 756 SDLGYPKSLHTLVLVFLYVNDTAGNASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTI 815
Query: 834 VIGVVAGIMTVILIILIVVMARYCRSKNKNGYEAGKKDHEDFFTPQQHDKSKKPKKDKKN 893
+I ++AG M VI++I + V+ R CR ++ K ++ +P Q +K K KK KK
Sbjct: 816 MIAIIAGAMVVIVVIFVTVLVR-CRHASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKKR 874
Query: 894 KKSKQPLYSSIVTVEASKPNGQRYDSVNEKLS-----DSPSMGRY-----RSVNGGPGSP 943
K K L + VT+E SKP+ ++ +N +S + S+GR+ P SP
Sbjct: 875 KSPKSSLL-NFVTIEESKPDDAVHEPINGTISLPAELEEQSIGRFDWGPAPPTTFKPNSP 933
Query: 944 DLARHYKSSSPLPTVQLHPQSPTAGKKHQAVQDLPPANTFVGAGDNI----SIGSDHCSE 999
DLA+HYKS+SP P L P +P + KKH +Q+LP NTFVG D + S SDH S
Sbjct: 934 DLAKHYKSASPQPAFHLKPDTPVSVKKHHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSA 993
Query: 1000 YSCQTN--------------NKYSKQPFRRVT---------FSVVSQPQDPHQ------- 1029
C + N +SK VT F + + ++
Sbjct: 994 SECSSQGGFKTKGPLHTRQCNSHSKSDNIPVTPQKCPSSTGFHIQENEESHYESQRRVTF 1053
Query: 1030 ----GSLQSCYDSGLEESETPSSKSSSGPRLGALPLPEDNYERTTPDGSVD----SRPLP 1081
GS +SC DSGL + E S + L + ++ Y++ +PD + S P
Sbjct: 1054 HLPDGSQESCSDSGLGDHEPVGSGTLISHPLPLVQPQDEFYDQASPDKRTEADGNSDPNS 1113
Query: 1082 DVAL--------TGKCTRECDEYGHSDSCWMPVRTSPERKKSQPKLSTFMPVDERGSQEK 1133
D L T CT+EC GHSD+CWMP P + P LSTF P E ++K
Sbjct: 1114 DGPLGPRGLAEATEMCTQECLVLGHSDNCWMPPGLGPYQHPKSP-LSTFAPQKEWVKKDK 1172
Query: 1134 LANGEA---AIMGDRNRNLLNKKLTSSYETFSAASFSKNEEANPEDIPLTKTGEYKPSPV 1190
L NG A D NRN N + + + + N ++ DIPL YK +
Sbjct: 1173 LVNGHTLTRAWKEDSNRNQFNDR-----KQYGSNEGHFNNGSHMTDIPLANLKSYKQAGG 1227
Query: 1191 NTLTRRE 1197
T + +E
Sbjct: 1228 ATESPKE 1234
>gi|14589946 protocadherin 11 Y-linked isoform c [Homo sapiens]
Length = 1340
Score = 615 bits (1585), Expect = e-175
Identities = 410/1123 (36%), Positives = 608/1123 (54%), Gaps = 87/1123 (7%)
Query: 36 YRLAEEGPADVRIGNVASDLGI-------VTGSGEVTFSLESGS-EYLKIDNLTGELSTS 87
Y + EE P +V IGN+ DL + +T + + ++G ++I+ TGE+ T+
Sbjct: 60 YTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTT 119
Query: 88 ERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDINDNTPTFPSPV 147
RIDREKL C I + CF + EV+++ P + + L + + ++ DINDN P FP+ V
Sbjct: 120 GARIDREKL--CAGIPRDEHCFYEVEVAIL-PDEIF-RLVKIRFLIEDINDNAPLFPATV 175
Query: 148 LTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYP 207
+ +++ EN + + Y LP A D D G NG++ YEL++ S+ D P
Sbjct: 176 INISIPENSAINSKYTLPAAVDPDVGINGVQNYELIK----------SQNIFGLDVIETP 225
Query: 208 GGGGNGASGGGSGGSKRRLDASEGGGGTNPGG---RSSVFELQVADTPDGEKQPQLIVKG 264
G + D GG RSS LQV+ T + P + +
Sbjct: 226 EGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHP-VFKET 284
Query: 265 VYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESV-RRLLRLDETSGWLSVL 323
E + EN+ GT + QL A D D+G N +I + F ++ RRL L+ T+G +++
Sbjct: 285 EIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIK 344
Query: 324 HRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVA 383
+DREE + V+A D G P +A V++N+ D NDNVPSI+IR I P+ D V
Sbjct: 345 EPLDREETPNHKLLVLASDGGLMPA--RAMVLVNVTDVNDNVPSIDIRYIVN-PVNDTVV 401
Query: 384 NVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTS 443
++E++ ++T IAL+ V+D+D NG VTC ++PF+L+P + + L +
Sbjct: 402 -LSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQ-------FLLENA 453
Query: 444 TPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIP 503
LDYE+T+E+ + ++A D+G P L+ + L +KV D NDN P+F QS V V PENN P
Sbjct: 454 AYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSP 513
Query: 504 GERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVN 563
G ++ V ATDADSG NAEI Y L F++D +G + V LDRE+ D+Y F +
Sbjct: 514 GIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTIL 573
Query: 564 AKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGR 623
AKD G+P L + TV V + D+NDN P F + + FYV ENL + VG++TV D D G
Sbjct: 574 AKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGD 633
Query: 624 NAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSL 683
N+ ++L I + N+ F+I++ TG I +SFDRE Q +YTF VKA DGG RS++A V++
Sbjct: 634 NSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTI 693
Query: 684 FVMDENDNAPT-VTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPF 742
V+D NDN P + P N SY L+ PS+N TVV V+A D+D G+NA++ YSIVGGN
Sbjct: 694 NVVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTR 753
Query: 743 KLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQP-SQSTTTLVHVFVNESVSNATA 801
LF ID +G ++L+ K GLHR++V+ ND GQP S + +V++FVNESV+NAT
Sbjct: 754 DLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATL 813
Query: 802 IDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVMARYCRSKN 861
I+ + +S+ P+T + + + I++ VAG +TV+++I I + R CR
Sbjct: 814 INELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVR-CRQAP 872
Query: 862 KNGYEAGKKDHEDFFTPQQHDKSKKPKKDKKNKKSKQP--LYSSIVTVEASKPNGQRYDS 919
+ ++ TP ++ K KK KK P L ++VT+E +K + D
Sbjct: 873 HLKAAQKNMQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNVVTIEETKADDVDSDG 932
Query: 920 VNEKLS-----DSPSMGRYRSVNG----GPGSPDLARHYKSSSPLPTVQLHPQSPTAGKK 970
L + +MG+Y V P SPDLARHYKS+SP P Q+ P++P K
Sbjct: 933 NRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETP-LNLK 991
Query: 971 HQAVQDLPPANTFVGAGDNISIGSDHCSEYSCQTNNKYSKQPFRRVTFSVVSQPQDPH-- 1028
H +Q+LP NTFV A D+IS S S+ ++ Y F V SV ++P
Sbjct: 992 HHIIQELPLDNTFV-ACDSISNCSSSSSDPYSVSDCGYPVTTF-EVPVSVHTRPSQRRVT 1049
Query: 1029 ----QGSLQSCYDSGLEESETPSSKSSSGPRLGALPL---PEDNYERTTP------DGSV 1075
+GS +S D GL + + S S+S LPL E+ ++R TP DG+
Sbjct: 1050 FHLPEGSQESSSDGGLGDHDAGSLTSTS----HGLPLGYPQEEYFDRATPSNRTEGDGNS 1105
Query: 1076 D--SRPLPDV-----------ALTGKCTRECDEYGHSDSCWMP 1105
D S +P + + CT+EC YGHSD+CWMP
Sbjct: 1106 DPESTFIPGLKKEITVQPTVEEASDNCTQECLIYGHSDACWMP 1148
>gi|14589922 protocadherin 11 X-linked isoform d [Homo sapiens]
Length = 1337
Score = 605 bits (1559), Expect = e-172
Identities = 406/1150 (35%), Positives = 604/1150 (52%), Gaps = 112/1150 (9%)
Query: 36 YRLAEEGPADVRIGNVASDLGI-------VTGSGEVTFSLESGS-EYLKIDNLTGELSTS 87
Y + EE P +V IG++ DL + +T + + ++G ++I+ TGE+ T+
Sbjct: 28 YTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVYKTGDVPLIRIEEDTGEIFTT 87
Query: 88 ERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDINDNTPTFPSPV 147
RIDREKL C I + CF + EV+++ P + + L + + ++ DINDN P FP+ V
Sbjct: 88 GARIDREKL--CAGIPRDEHCFYEVEVAIL-PDEIF-RLVKIRFLIEDINDNAPLFPATV 143
Query: 148 LTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYP 207
+ +++ EN + + Y LP A D D G NG++ YEL++ S+ D P
Sbjct: 144 INISIPENSAINSKYTLPAAVDPDVGINGVQNYELIK----------SQNIFGLDVIETP 193
Query: 208 GGGGNGASGGGSGGSKRRLDASEGGGGTNPGG---RSSVFELQVADTPDGEKQPQLIVKG 264
G + D GG RSS LQV+ T + P + +
Sbjct: 194 EGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHP-VFKET 252
Query: 265 VYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESV-RRLLRLDETSGWLSVL 323
E + EN+ GT + QL A D D+G N +I + F ++ RRL L+ T+G +++
Sbjct: 253 EIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIK 312
Query: 324 HRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVA 383
+DREE + V+A D G P +A V++N+ D NDNVPSI+IR I P+ D V
Sbjct: 313 EPLDREETPNHKLLVLASDGGLMPA--RAMVLVNVTDVNDNVPSIDIRYIVN-PVNDTVV 369
Query: 384 NVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTS 443
++E++ ++T IAL+ V+D+D NG VTC ++PF+L+P + + L T+
Sbjct: 370 -LSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQ-------FLLETA 421
Query: 444 TPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIP 503
LDYE+T+E+ + ++A D+G P L+ + L +KV D NDN P+F QS V V PENN P
Sbjct: 422 AYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSP 481
Query: 504 GERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVN 563
G ++ V A DADSG NA+I Y L F++D +G + V LDRE+ D+Y F +
Sbjct: 482 GIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTIL 541
Query: 564 AKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGR 623
AKD G+P L + TV V + D+NDN P F + + FYV ENL + VG++TV D D G
Sbjct: 542 AKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGD 601
Query: 624 NAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSL 683
N+ ++L I + N+ F+I++ TG I +SFDRE Q +YTF VKA DGG RS++A V++
Sbjct: 602 NSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTI 661
Query: 684 FVMDENDNAPT-VTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPF 742
V+D NDN P + P N SY L+ PS+N TVV V+A D+D G+NA++ YSIVGGN
Sbjct: 662 NVVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTR 721
Query: 743 KLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQP-SQSTTTLVHVFVNESVSNATA 801
LF ID +G ++L+ K GLHR++V+ ND GQP S + +V++FVNESV+NAT
Sbjct: 722 DLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATL 781
Query: 802 IDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVMARYCRSKN 861
I+ + +S P+T + + + I++ VAG +TV+++I I + R CR
Sbjct: 782 INELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVR-CRQAP 840
Query: 862 KNGYEAGKKDHEDFFTPQQHDKSKKPKKDKKNKKSKQP--LYSSIVTVEASKPNGQRYDS 919
K + ++ TP ++ K KK KK P L + VT+E +K + D
Sbjct: 841 HLKAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDG 900
Query: 920 VNEKLS-----DSPSMGRYRSVNG----GPGSPDLARHYKSSSPLPTVQLHPQSPTAGKK 970
L + +MG+Y V P SPDLARHYKS+SP P Q+ P++P K
Sbjct: 901 NRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETP-LNSK 959
Query: 971 HQAVQDLPPANTFVGAGDNISIGSDHCSEYSCQ-----------TNNKYSKQPFRRVTFS 1019
H +Q+LP NTFV S YS + +++ P + V S
Sbjct: 960 HHIIQELPLDNTFVACDSISKCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRPPMKEVVRS 1019
Query: 1020 -------------VVSQPQDPH-------QGSLQSCYDSGLEESETPSSKSSSGPRLGAL 1059
+ QPQ +GS +S D GL + + S S+S L
Sbjct: 1020 CTPMKESTTMEIWIHPQPQSQRRVTFHLPEGSQESSSDGGLGDHDAGSLTSTS----HGL 1075
Query: 1060 PL---PEDNYERTTP------DGSVD--SRPLPDV-------------ALTGKCTRECDE 1095
PL E+ ++R TP DG+ D S +P + + CT+EC
Sbjct: 1076 PLGYPQEEYFDRATPSNRTEGDGNSDPESTFIPGLKKAAEITVQPTVEEASDNCTQECLI 1135
Query: 1096 YGHSDSCWMP 1105
YGHSD+CWMP
Sbjct: 1136 YGHSDACWMP 1145
>gi|14589920 protocadherin 11 X-linked isoform c [Homo sapiens]
Length = 1347
Score = 600 bits (1546), Expect = e-171
Identities = 405/1160 (34%), Positives = 603/1160 (51%), Gaps = 122/1160 (10%)
Query: 36 YRLAEEGPADVRIGNVASDLGI-------VTGSGEVTFSLESGS-EYLKIDNLTGELSTS 87
Y + EE P +V IG++ DL + +T + + ++G ++I+ TGE+ T+
Sbjct: 28 YTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVYKTGDVPLIRIEEDTGEIFTT 87
Query: 88 ERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDINDNTPTFPSPV 147
RIDREKL C I + CF + EV+++ P + + L + + ++ DINDN P FP+ V
Sbjct: 88 GARIDREKL--CAGIPRDEHCFYEVEVAIL-PDEIF-RLVKIRFLIEDINDNAPLFPATV 143
Query: 148 LTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYP 207
+ +++ EN + + Y LP A D D G NG++ YEL++ S+ D P
Sbjct: 144 INISIPENSAINSKYTLPAAVDPDVGINGVQNYELIK----------SQNIFGLDVIETP 193
Query: 208 GGGGNGASGGGSGGSKRRLDASEGGGGTNPGG---RSSVFELQVADTPDGEKQPQLIVKG 264
G + D GG RSS LQV+ T + P + +
Sbjct: 194 EGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHP-VFKET 252
Query: 265 VYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESV-RRLLRLDETSGWLSVL 323
E + EN+ GT + QL A D D+G N +I + F ++ RRL L+ T+G +++
Sbjct: 253 EIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIK 312
Query: 324 HRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVA 383
+DREE + V+A D G P +A V++N+ D NDNVPSI+IR I P+ D V
Sbjct: 313 EPLDREETPNHKLLVLASDGGLMPA--RAMVLVNVTDVNDNVPSIDIRYIVN-PVNDTVV 369
Query: 384 NVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTS 443
++E++ ++T IAL+ V+D+D NG VTC ++PF+L+P + + L T+
Sbjct: 370 -LSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQ-------FLLETA 421
Query: 444 TPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIP 503
LDYE+T+E+ + ++A D+G P L+ + L +KV D NDN P+F QS V V PENN P
Sbjct: 422 AYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSP 481
Query: 504 GERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVN 563
G ++ V A DADSG NA+I Y L F++D +G + V LDRE+ D+Y F +
Sbjct: 482 GIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTIL 541
Query: 564 AKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGR 623
AKD G+P L + TV V + D+NDN P F + + FYV ENL + VG++TV D D G
Sbjct: 542 AKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGD 601
Query: 624 NAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSL 683
N+ ++L I + N+ F+I++ TG I +SFDRE Q +YTF VKA DGG RS++A V++
Sbjct: 602 NSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTI 661
Query: 684 FVMDENDNAPT-VTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPF 742
V+D NDN P + P N SY L+ PS+N TVV V+A D+D G+NA++ YSIVGGN
Sbjct: 662 NVVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTR 721
Query: 743 KLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQP-SQSTTTLVHVFVNESVSNATA 801
LF ID +G ++L+ K GLHR++V+ ND GQP S + +V++FVNESV+NAT
Sbjct: 722 DLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATL 781
Query: 802 IDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVMARYCRSKN 861
I+ + +S P+T + + + I++ VAG +TV+++I I + R CR
Sbjct: 782 INELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVR-CRQAP 840
Query: 862 KNGYEAGKKDHEDFFTPQQHDKSKKPKKDKKNKKSKQP--LYSSIVTVEASKPNGQRYDS 919
K + ++ TP ++ K KK KK P L + VT+E +K + D
Sbjct: 841 HLKAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDG 900
Query: 920 VNEKLS-----DSPSMGRYRSVNG----GPGSPDLARHYKSSSPLPTVQLHPQSPTAGKK 970
L + +MG+Y V P SPDLARHYKS+SP P Q+ P++P K
Sbjct: 901 NRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETP-LNSK 959
Query: 971 HQAVQDLPPANTFVGAGDNISIGSDHCSEYSCQ-----------TNNKYSKQPFRRV--- 1016
H +Q+LP NTFV S YS + +++ P + V
Sbjct: 960 HHIIQELPLDNTFVACDSISKCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRPPMKEVVRS 1019
Query: 1017 --------TFSVVSQPQDPH-------------------QGSLQSCYDSGLEESETPSSK 1049
T + PQ +GS +S D GL + + S
Sbjct: 1020 CTPMKESTTMEIWIHPQPQRKSEGKVAGKSQRRVTFHLPEGSQESSSDGGLGDHDAGSLT 1079
Query: 1050 SSSGPRLGALPL---PEDNYERTTP------DGSVD--SRPLPDV-------------AL 1085
S+S LPL E+ ++R TP DG+ D S +P +
Sbjct: 1080 STS----HGLPLGYPQEEYFDRATPSNRTEGDGNSDPESTFIPGLKKAAEITVQPTVEEA 1135
Query: 1086 TGKCTRECDEYGHSDSCWMP 1105
+ CT+EC YGHSD+CWMP
Sbjct: 1136 SDNCTQECLIYGHSDACWMP 1155
>gi|14589918 protocadherin 11 X-linked isoform b precursor [Homo
sapiens]
Length = 1025
Score = 586 bits (1510), Expect = e-167
Identities = 377/1025 (36%), Positives = 564/1025 (55%), Gaps = 55/1025 (5%)
Query: 36 YRLAEEGPADVRIGNVASDLGI-------VTGSGEVTFSLESGS-EYLKIDNLTGELSTS 87
Y + EE P +V IG++ DL + +T + + ++G ++I+ TGE+ T+
Sbjct: 28 YTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVYKTGDVPLIRIEEDTGEIFTT 87
Query: 88 ERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDINDNTPTFPSPV 147
RIDREKL C I + CF + EV+++ P + + L + + ++ DINDN P FP+ V
Sbjct: 88 GARIDREKL--CAGIPRDEHCFYEVEVAIL-PDEIF-RLVKIRFLIEDINDNAPLFPATV 143
Query: 148 LTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYP 207
+ +++ EN + + Y LP A D D G NG++ YEL++ S+ D P
Sbjct: 144 INISIPENSAINSKYTLPAAVDPDVGINGVQNYELIK----------SQNIFGLDVIETP 193
Query: 208 GGGGNGASGGGSGGSKRRLDASEGGGGTNPGG---RSSVFELQVADTPDGEKQPQLIVKG 264
G + D GG RSS LQV+ T + P + +
Sbjct: 194 EGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHP-VFKET 252
Query: 265 VYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESV-RRLLRLDETSGWLSVL 323
E + EN+ GT + QL A D D+G N +I + F ++ RRL L+ T+G +++
Sbjct: 253 EIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIK 312
Query: 324 HRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVA 383
+DREE + V+A D G P +A V++N+ D NDNVPSI+IR I P+ D V
Sbjct: 313 EPLDREETPNHKLLVLASDGGLMPA--RAMVLVNVTDVNDNVPSIDIRYIVN-PVNDTVV 369
Query: 384 NVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTS 443
++E++ ++T IAL+ V+D+D NG VTC ++PF+L+P + + L T+
Sbjct: 370 -LSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQ-------FLLETA 421
Query: 444 TPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIP 503
LDYE+T+E+ + ++A D+G P L+ + L +KV D NDN P+F QS V V PENN P
Sbjct: 422 AYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSP 481
Query: 504 GERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVN 563
G ++ V A DADSG NA+I Y L F++D +G + V LDRE+ D+Y F +
Sbjct: 482 GIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTIL 541
Query: 564 AKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGR 623
AKD G+P L + TV V + D+NDN P F + + FYV ENL + VG++TV D D G
Sbjct: 542 AKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGD 601
Query: 624 NAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSL 683
N+ ++L I + N+ F+I++ TG I +SFDRE Q +YTF VKA DGG RS++A V++
Sbjct: 602 NSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTI 661
Query: 684 FVMDENDNAPT-VTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPF 742
V+D NDN P + P N SY L+ PS+N TVV V+A D+D G+NA++ YSIVGGN
Sbjct: 662 NVVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTR 721
Query: 743 KLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQP-SQSTTTLVHVFVNESVSNATA 801
LF ID +G ++L+ K GLHR++V+ ND GQP S + +V++FVNESV+NAT
Sbjct: 722 DLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATL 781
Query: 802 IDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVMARYCRSKN 861
I+ + +S P+T + + + I++ VAG +TV+++I I + R CR
Sbjct: 782 INELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVR-CRQAP 840
Query: 862 KNGYEAGKKDHEDFFTPQQHDKSKKPKKDKKNKKSKQP--LYSSIVTVEASKPNGQRYDS 919
K + ++ TP ++ K KK KK P L + VT+E +K + D
Sbjct: 841 HLKAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDG 900
Query: 920 VNEKLS-----DSPSMGRYRSVNG----GPGSPDLARHYKSSSPLPTVQLHPQSPTAGKK 970
L + +MG+Y V P SPDLARHYKS+SP P Q+ P++P K
Sbjct: 901 NRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETP-LNSK 959
Query: 971 HQAVQDLPPANTFVGAGDNISIGSDHCSEYSCQTNNKYSKQPFRRVTFSVVSQPQDPHQG 1030
H +Q+LP NTFV A D+IS S S+ ++ Y F V SV ++P D
Sbjct: 960 HHIIQELPLDNTFV-ACDSISKCSSSSSDPYSVSDCGYPVTTF-EVPVSVHTRPTDSRTS 1017
Query: 1031 SLQSC 1035
+++ C
Sbjct: 1018 TIEIC 1022
>gi|14589944 protocadherin 11 Y-linked isoform b [Homo sapiens]
Length = 1048
Score = 583 bits (1504), Expect = e-166
Identities = 377/1016 (37%), Positives = 561/1016 (55%), Gaps = 55/1016 (5%)
Query: 36 YRLAEEGPADVRIGNVASDLGI-------VTGSGEVTFSLESGS-EYLKIDNLTGELSTS 87
Y + EE P +V IGN+ DL + +T + + ++G ++I+ TGE+ T+
Sbjct: 60 YTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTT 119
Query: 88 ERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDINDNTPTFPSPV 147
RIDREKL C I + CF + EV+++ P + + L + + ++ DINDN P FP+ V
Sbjct: 120 GARIDREKL--CAGIPRDEHCFYEVEVAIL-PDEIF-RLVKIRFLIEDINDNAPLFPATV 175
Query: 148 LTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYP 207
+ +++ EN + + Y LP A D D G NG++ YEL++ S+ D P
Sbjct: 176 INISIPENSAINSKYTLPAAVDPDVGINGVQNYELIK----------SQNIFGLDVIETP 225
Query: 208 GGGGNGASGGGSGGSKRRLDASEGGGGTNPGG---RSSVFELQVADTPDGEKQPQLIVKG 264
G + D GG RSS LQV+ T + P + +
Sbjct: 226 EGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHP-VFKET 284
Query: 265 VYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESV-RRLLRLDETSGWLSVL 323
E + EN+ GT + QL A D D+G N +I + F ++ RRL L+ T+G +++
Sbjct: 285 EIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIK 344
Query: 324 HRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVA 383
+DREE + V+A D G P +A V++N+ D NDNVPSI+IR I P+ D V
Sbjct: 345 EPLDREETPNHKLLVLASDGGLMPA--RAMVLVNVTDVNDNVPSIDIRYIVN-PVNDTVV 401
Query: 384 NVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTS 443
++E++ ++T IAL+ V+D+D NG VTC ++PF+L+P + + L +
Sbjct: 402 -LSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQ-------FLLENA 453
Query: 444 TPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIP 503
LDYE+T+E+ + ++A D+G P L+ + L +KV D NDN P+F QS V V PENN P
Sbjct: 454 AYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSP 513
Query: 504 GERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVN 563
G ++ V ATDADSG NAEI Y L F++D +G + V LDRE+ D+Y F +
Sbjct: 514 GIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTIL 573
Query: 564 AKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGR 623
AKD G+P L + TV V + D+NDN P F + + FYV ENL + VG++TV D D G
Sbjct: 574 AKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGD 633
Query: 624 NAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSL 683
N+ ++L I + N+ F+I++ TG I +SFDRE Q +YTF VKA DGG RS++A V++
Sbjct: 634 NSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTI 693
Query: 684 FVMDENDNAPT-VTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPF 742
V+D NDN P + P N SY L+ PS+N TVV V+A D+D G+NA++ YSIVGGN
Sbjct: 694 NVVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTR 753
Query: 743 KLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQP-SQSTTTLVHVFVNESVSNATA 801
LF ID +G ++L+ K GLHR++V+ ND GQP S + +V++FVNESV+NAT
Sbjct: 754 DLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATL 813
Query: 802 IDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVMARYCRSKN 861
I+ + +S+ P+T + + + I++ VAG +TV+++I I + R CR
Sbjct: 814 INELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVR-CRQAP 872
Query: 862 KNGYEAGKKDHEDFFTPQQHDKSKKPKKDKKNKKSKQP--LYSSIVTVEASKPNGQRYDS 919
+ ++ TP ++ K KK KK P L ++VT+E +K + D
Sbjct: 873 HLKAAQKNMQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNVVTIEETKADDVDSDG 932
Query: 920 VNEKLS-----DSPSMGRYRSVNG----GPGSPDLARHYKSSSPLPTVQLHPQSPTAGKK 970
L + +MG+Y V P SPDLARHYKS+SP P Q+ P++P K
Sbjct: 933 NRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETP-LNLK 991
Query: 971 HQAVQDLPPANTFVGAGDNISIGSDHCSEYSCQTNNKYSKQPFRRVTFSVVSQPQD 1026
H +Q+LP NTFV A D+IS S S+ ++ Y F V SV ++P D
Sbjct: 992 HHIIQELPLDNTFV-ACDSISNCSSSSSDPYSVSDCGYPVTTF-EVPVSVHTRPTD 1045
>gi|14589942 protocadherin 11 Y-linked isoform a [Homo sapiens]
Length = 1037
Score = 583 bits (1504), Expect = e-166
Identities = 377/1016 (37%), Positives = 561/1016 (55%), Gaps = 55/1016 (5%)
Query: 36 YRLAEEGPADVRIGNVASDLGI-------VTGSGEVTFSLESGS-EYLKIDNLTGELSTS 87
Y + EE P +V IGN+ DL + +T + + ++G ++I+ TGE+ T+
Sbjct: 49 YTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTT 108
Query: 88 ERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDINDNTPTFPSPV 147
RIDREKL C I + CF + EV+++ P + + L + + ++ DINDN P FP+ V
Sbjct: 109 GARIDREKL--CAGIPRDEHCFYEVEVAIL-PDEIF-RLVKIRFLIEDINDNAPLFPATV 164
Query: 148 LTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYP 207
+ +++ EN + + Y LP A D D G NG++ YEL++ S+ D P
Sbjct: 165 INISIPENSAINSKYTLPAAVDPDVGINGVQNYELIK----------SQNIFGLDVIETP 214
Query: 208 GGGGNGASGGGSGGSKRRLDASEGGGGTNPGG---RSSVFELQVADTPDGEKQPQLIVKG 264
G + D GG RSS LQV+ T + P + +
Sbjct: 215 EGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHP-VFKET 273
Query: 265 VYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESV-RRLLRLDETSGWLSVL 323
E + EN+ GT + QL A D D+G N +I + F ++ RRL L+ T+G +++
Sbjct: 274 EIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIK 333
Query: 324 HRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVA 383
+DREE + V+A D G P +A V++N+ D NDNVPSI+IR I P+ D V
Sbjct: 334 EPLDREETPNHKLLVLASDGGLMPA--RAMVLVNVTDVNDNVPSIDIRYIVN-PVNDTVV 390
Query: 384 NVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTS 443
++E++ ++T IAL+ V+D+D NG VTC ++PF+L+P + + L +
Sbjct: 391 -LSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQ-------FLLENA 442
Query: 444 TPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIP 503
LDYE+T+E+ + ++A D+G P L+ + L +KV D NDN P+F QS V V PENN P
Sbjct: 443 AYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSP 502
Query: 504 GERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVN 563
G ++ V ATDADSG NAEI Y L F++D +G + V LDRE+ D+Y F +
Sbjct: 503 GIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTIL 562
Query: 564 AKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGR 623
AKD G+P L + TV V + D+NDN P F + + FYV ENL + VG++TV D D G
Sbjct: 563 AKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGD 622
Query: 624 NAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSL 683
N+ ++L I + N+ F+I++ TG I +SFDRE Q +YTF VKA DGG RS++A V++
Sbjct: 623 NSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTI 682
Query: 684 FVMDENDNAPT-VTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPF 742
V+D NDN P + P N SY L+ PS+N TVV V+A D+D G+NA++ YSIVGGN
Sbjct: 683 NVVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTR 742
Query: 743 KLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQP-SQSTTTLVHVFVNESVSNATA 801
LF ID +G ++L+ K GLHR++V+ ND GQP S + +V++FVNESV+NAT
Sbjct: 743 DLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATL 802
Query: 802 IDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVMARYCRSKN 861
I+ + +S+ P+T + + + I++ VAG +TV+++I I + R CR
Sbjct: 803 INELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVR-CRQAP 861
Query: 862 KNGYEAGKKDHEDFFTPQQHDKSKKPKKDKKNKKSKQP--LYSSIVTVEASKPNGQRYDS 919
+ ++ TP ++ K KK KK P L ++VT+E +K + D
Sbjct: 862 HLKAAQKNMQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNVVTIEETKADDVDSDG 921
Query: 920 VNEKLS-----DSPSMGRYRSVNG----GPGSPDLARHYKSSSPLPTVQLHPQSPTAGKK 970
L + +MG+Y V P SPDLARHYKS+SP P Q+ P++P K
Sbjct: 922 NRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETP-LNLK 980
Query: 971 HQAVQDLPPANTFVGAGDNISIGSDHCSEYSCQTNNKYSKQPFRRVTFSVVSQPQD 1026
H +Q+LP NTFV A D+IS S S+ ++ Y F V SV ++P D
Sbjct: 981 HHIIQELPLDNTFV-ACDSISNCSSSSSDPYSVSDCGYPVTTF-EVPVSVHTRPTD 1034
>gi|7657443 protocadherin 11 X-linked isoform a precursor [Homo
sapiens]
Length = 1021
Score = 580 bits (1495), Expect = e-165
Identities = 375/1014 (36%), Positives = 559/1014 (55%), Gaps = 55/1014 (5%)
Query: 36 YRLAEEGPADVRIGNVASDLGI-------VTGSGEVTFSLESGS-EYLKIDNLTGELSTS 87
Y + EE P +V IG++ DL + +T + + ++G ++I+ TGE+ T+
Sbjct: 28 YTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVYKTGDVPLIRIEEDTGEIFTT 87
Query: 88 ERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDINDNTPTFPSPV 147
RIDREKL C I + CF + EV+++ P + + L + + ++ DINDN P FP+ V
Sbjct: 88 GARIDREKL--CAGIPRDEHCFYEVEVAIL-PDEIF-RLVKIRFLIEDINDNAPLFPATV 143
Query: 148 LTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYP 207
+ +++ EN + + Y LP A D D G NG++ YEL++ S+ D P
Sbjct: 144 INISIPENSAINSKYTLPAAVDPDVGINGVQNYELIK----------SQNIFGLDVIETP 193
Query: 208 GGGGNGASGGGSGGSKRRLDASEGGGGTNPGG---RSSVFELQVADTPDGEKQPQLIVKG 264
G + D GG RSS LQV+ T + P + +
Sbjct: 194 EGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHP-VFKET 252
Query: 265 VYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESV-RRLLRLDETSGWLSVL 323
E + EN+ GT + QL A D D+G N +I + F ++ RRL L+ T+G +++
Sbjct: 253 EIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIK 312
Query: 324 HRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVA 383
+DREE + V+A D G P +A V++N+ D NDNVPSI+IR I P+ D V
Sbjct: 313 EPLDREETPNHKLLVLASDGGLMPA--RAMVLVNVTDVNDNVPSIDIRYIVN-PVNDTVV 369
Query: 384 NVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTS 443
++E++ ++T IAL+ V+D+D NG VTC ++PF+L+P + + L T+
Sbjct: 370 -LSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQ-------FLLETA 421
Query: 444 TPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIP 503
LDYE+T+E+ + ++A D+G P L+ + L +KV D NDN P+F QS V V PENN P
Sbjct: 422 AYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSP 481
Query: 504 GERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVN 563
G ++ V A DADSG NA+I Y L F++D +G + V LDRE+ D+Y F +
Sbjct: 482 GIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTIL 541
Query: 564 AKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGR 623
AKD G+P L + TV V + D+NDN P F + + FYV ENL + VG++TV D D G
Sbjct: 542 AKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGD 601
Query: 624 NAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSL 683
N+ ++L I + N+ F+I++ TG I +SFDRE Q +YTF VKA DGG RS++A V++
Sbjct: 602 NSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTI 661
Query: 684 FVMDENDNAPT-VTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPF 742
V+D NDN P + P N SY L+ PS+N TVV V+A D+D G+NA++ YSIVGGN
Sbjct: 662 NVVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTR 721
Query: 743 KLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQP-SQSTTTLVHVFVNESVSNATA 801
LF ID +G ++L+ K GLHR++V+ ND GQP S + +V++FVNESV+NAT
Sbjct: 722 DLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATL 781
Query: 802 IDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVMARYCRSKN 861
I+ + +S P+T + + + I++ VAG +TV+++I I + R CR
Sbjct: 782 INELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVR-CRQAP 840
Query: 862 KNGYEAGKKDHEDFFTPQQHDKSKKPKKDKKNKKSKQP--LYSSIVTVEASKPNGQRYDS 919
K + ++ TP ++ K KK KK P L + VT+E +K + D
Sbjct: 841 HLKAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDG 900
Query: 920 VNEKLS-----DSPSMGRYRSVNG----GPGSPDLARHYKSSSPLPTVQLHPQSPTAGKK 970
L + +MG+Y V P SPDLARHYKS+SP P Q+ P++P K
Sbjct: 901 NRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETP-LNSK 959
Query: 971 HQAVQDLPPANTFVGAGDNISIGSDHCSEYSCQTNNKYSKQPFRRVTFSVVSQP 1024
H +Q+LP NTFV A D+IS S S+ ++ Y F V SV ++P
Sbjct: 960 HHIIQELPLDNTFV-ACDSISKCSSSSSDPYSVSDCGYPVTTF-EVPVSVHTRP 1011
>gi|190194360 protocadherin 20 [Homo sapiens]
Length = 951
Score = 369 bits (948), Expect = e-102
Identities = 279/874 (31%), Positives = 436/874 (49%), Gaps = 67/874 (7%)
Query: 26 SLAAAKQLLRYRLAEEGPADVRIGNVASDLGIVTGSG-------------------EVTF 66
S + A +LL Y L E PA V IG++A DL ++ S ++F
Sbjct: 61 SYSRATELL-YSLNEGLPAGVLIGSLAEDLRLLPRSAGRPDPQSQLPERTGAEWNPPLSF 119
Query: 67 SLES---GSEYLKIDNLTGELSTSERRIDREKL------------PQCQMIFDENECFLD 111
SL S +Y+ +DN +GEL TS + IDRE L + C L
Sbjct: 120 SLASRGLSGQYVTLDNRSGELHTSAQEIDREALCVEGGGGTAWSGSVSISSSPSDSCLLL 179
Query: 112 FEVSVIGPSQSWVDLFEGQVIVLDINDNTPTFPSPVLTLTVEENRPVGT-LYLLPTATDR 170
+V V+ Q + + ++ + DINDN P FP +++ V EN PV T L + A D
Sbjct: 180 LDVLVL--PQEYFRFVKVKIAIRDINDNAPQFPVSQISVWVPENAPVNTRLAIEHPAVDP 237
Query: 171 DFGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASE 230
D G NG++ Y LL G E G + PY GA + + +E
Sbjct: 238 DVGINGVQTYRLLDYHGMFTLDVEENENG--ERTPYLIV--MGALDRETQDQYVSIIIAE 293
Query: 231 GGGGTNPGGRSSVFELQVADTPDGEKQPQLIVKGVYEADLAENSAPGTPILQLRAADLDV 290
GG G S+ + ++D D L + N+ GTPI ++A D D+
Sbjct: 294 DGGSPPLLG-SATLTIGISDINDN---CPLFTDSQINVTVYGNATVGTPIAAVQAVDKDL 349
Query: 291 GVNGQIEYVFGAAT-ESVRRLLRLDETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKT 349
G N QI Y + ++ + L LDE +G + + +I + + T++A G P
Sbjct: 350 GTNAQITYSYSQKVPQASKDLFHLDENTGVIKLFSKIGGSVLESHKLTILANGPGCIPAV 409
Query: 350 DKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENG 409
T +++I P I R I DGV + E V+TPIA + RD
Sbjct: 410 --ITALVSIIKVIFRPPEIVPRYIANEI--DGVVYLKELEPVNTPIAFFTI--RDPEGKY 463
Query: 410 VVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLS 469
V C + G+ PF+L P + Y L T+ P+DYE + + V +VA +S
Sbjct: 464 KVNCYLDGEGPFRLSPYKPYNNE-----YLLETTKPMDYELQQFYEVAVVAWNS--EGFH 516
Query: 470 SNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSLDS 529
+ V++ D NDN P+F Q ++E+ ENN P + + ATDADS + +++Y L
Sbjct: 517 VKRVIKVQLLDDNDNAPIFLQPLIELTIEENNSPNAFLTKLYATDADSEERGQVSYFLGP 576
Query: 530 SVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDND 589
F++D +G + V+T LDRE+ ++Y + V A D G P + TV + V DKNDN
Sbjct: 577 DAPSYFSLDSVTGILTVSTQLDREEKEKYRYTVRAVDCGKPPRESVATVALTVLDKNDNS 636
Query: 590 PKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYS 649
P+F+ F+F+V EN +G+++V DAD GRN ++L + ++IF I+ G + +
Sbjct: 637 PRFINKDFSFFVPENFPGYGEIGVISVTDADAGRNGWVALSVVNQSDIFVIDTGKGMLRA 696
Query: 650 TMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLPK-NISYTLLPP 708
+S DRE Q++YT V+AVDGG+P S+TA +++ ++D NDN P V P+ N+SY L+ P
Sbjct: 697 KVSLDREQQSSYTLWVEAVDGGEPALSSTAKITILLLDINDNPPLVLFPQSNMSYLLVLP 756
Query: 709 SSNVRTVVATVLATDSDDGINADLNYSIVG--GNPFKLFEIDPTSGVVSLVGKLTQKHYG 766
S+ + V V A D D G+NA + YSI+G G + F IDP +G ++L L Q YG
Sbjct: 757 STLPGSPVTEVYAVDKDTGMNAVIAYSIIGRRGPRPESFRIDPKTGNITLEEALLQTDYG 816
Query: 767 LHRLVVQVNDSGQPSQ-STTTLVHVFVNESVSNATAIDSQIARSLHIPLTQ---DIAGDP 822
LHRL+V+V+D G P +T +V++FVN++VSN + I+S + + I + + I+ +P
Sbjct: 817 LHRLLVKVSDHGYPEPLHSTVMVNLFVNDTVSNESYIESLLRKEPEINIEEKEPQISIEP 876
Query: 823 SYEISKQRLSIVIGVVAGIMTVILIILIVVMARY 856
++ + + V ++++ I L+ M Y
Sbjct: 877 THRKVESVSCMPTLVALSVISLGSITLVTGMGIY 910
>gi|14589916 protocadherin 10 isoform 1 precursor [Homo sapiens]
Length = 1040
Score = 309 bits (792), Expect = 9e-84
Identities = 230/711 (32%), Positives = 334/711 (46%), Gaps = 77/711 (10%)
Query: 19 LLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGI----VTGSGEVTFSLESGSEY 74
LL L + L Y + EE +GN+A DLG+ ++ G T S + Y
Sbjct: 5 LLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVP-NSRTPY 63
Query: 75 LKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVL 134
L ++ TG L +E+ IDRE++ C+ C L EV + P ++LF+ ++ VL
Sbjct: 64 LDLNLETGVLYVNEK-IDREQI--CKQ---SPSCVLHLEVFLENP----LELFQVEIEVL 113
Query: 135 DINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYEL---------LQE 185
DINDN P+FP P LT+ + E+ GT + L +A D D G N + YE+ +Q
Sbjct: 114 DINDNPPSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQT 173
Query: 186 PGGGGSGGESRRAGAADS----------APYPGGGGNGASGGGSGGSKRRLDASEGGGGT 235
G G E D GGGG G GG GG GG G
Sbjct: 174 QGDGNRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGG---------GGAGL 224
Query: 236 NPGGRSSVFELQVADTPDGEKQPQLIVKGVYEADLAENSAPGTPILQLRAADLDVGVNGQ 295
P + + L D + VY L ENS PGT ++QL A D D G NG+
Sbjct: 225 PPQQQRTGTALLTIRVLDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGE 284
Query: 296 IEYVFGA-ATESVRRLLRLDETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATV 354
+ Y F + + R L L +G L V +D EE + V A+D G V
Sbjct: 285 VVYSFSSHISPRARELFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKV 344
Query: 355 VLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCT 414
++ + D NDN P I + V+E T +AL V+DRD ENG V C
Sbjct: 345 LVRVLDANDNAPEISFSTVKEA--------VSEGAAPGTVVALFSVTDRDSEENGQVQCE 396
Query: 415 VVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSL 474
++GDVPF+LK + K Y + T PLD EA + + +VA D G P+LS++ S+
Sbjct: 397 LLGDVPFRLKSSF-------KNYYTIVTEAPLDREAGDSYTLTVVARDRGEPALSTSKSI 449
Query: 475 IVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSL------D 528
V+V D NDN P F Q V +VY ENN+PG + V ATD D G NA++AYS+
Sbjct: 450 QVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGANAQLAYSILECQIQG 509
Query: 529 SSVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIP-VLQGSTTVIVQVADKND 587
SV +I+ ++G + D EQ + F+V A+D G P L G+ TV + + D+ND
Sbjct: 510 MSVFTYVSINSENGYLYALRSFDYEQLKDFSFQVEARDAGSPQALAGNATVNILIVDQND 569
Query: 588 NDPKFMQDV-------FTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENN--NIF 638
N P + + + + +P + V +DAD G NA ++ I N N+F
Sbjct: 570 NAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTRVAAVDADDGENARLTYSIVRGNEMNLF 629
Query: 639 SIENDTGTIYST--MSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMD 687
++ TG + + + R+ Q Y ++ D G PP S+TAT+ + ++D
Sbjct: 630 RMDWRTGELRTARRVPAKRDPQRPYELVIEVRDHGQPPLSSTATLVVQLVD 680
Score = 230 bits (587), Expect = 5e-60
Identities = 244/918 (26%), Positives = 394/918 (42%), Gaps = 132/918 (14%)
Query: 246 LQVADTPDGEKQPQLIVKGVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATE 305
L + D P +P L V +++E++ PGT A D DVG N +Y
Sbjct: 113 LDINDNPPSFPEPDLTV------EISESATPGTRFPLESAFDPDVGTNSLRDYEI----- 161
Query: 306 SVRRLLRLD-ETSG------WLSVLHRIDREEVNQLRFTVMARDRG-------------- 344
+ LD +T G L + +DRE+ R+ + A D G
Sbjct: 162 TPNSYFSLDVQTQGDGNRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGG 221
Query: 345 -----QPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQ 399
Q +T A + + + D NDNVP+ + ++ E+ T + +
Sbjct: 222 AGLPPQQQRTGTALLTIRVLDSNDNVPAFDQPVY--------TVSLPENSPPGTLVIQLN 273
Query: 400 VSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIV 459
+D D+G+NG VV + P + + + L S LDYE + + V +
Sbjct: 274 ATDPDEGQNG----EVVYSFSSHISPRARELFGLSPRTGRLEVSGELDYEESPVYQVYVQ 329
Query: 460 AVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGK 519
A D G ++ ++ ++V+V D NDN P S V+ E PG VA TD DS +
Sbjct: 330 AKDLGPNAVPAHCKVLVRVLDANDNAPEISFSTVKEAVSEGAAPGTVVALFSVTDRDSEE 389
Query: 520 NAEIAYSLDSSV-MGIFAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTV 578
N ++ L V + + + I+ LDRE D Y V A+D+G P L S ++
Sbjct: 390 NGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLDREAGDSYTLTVVARDRGEPALSTSKSI 449
Query: 579 IVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEE----N 634
VQV+D NDN P+F Q V+ YV EN P + + V+ D D+G NA+++ I E
Sbjct: 450 QVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGANAQLAYSILECQIQG 509
Query: 635 NNIF---SIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSA-TATVSLFVMDEND 690
++F SI ++ G +Y+ SFD E ++F+V+A D G P A ATV++ ++D+ND
Sbjct: 510 MSVFTYVSINSENGYLYALRSFDYEQLKDFSFQVEARDAGSPQALAGNATVNILIVDQND 569
Query: 691 NAPTVTLPK-----NISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLF 745
NAP + P + +LP S+ ++ V A D+DDG NA L YSIV GN LF
Sbjct: 570 NAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTRVAAVDADDGENARLTYSIVRGNEMNLF 629
Query: 746 EIDPTSGVVSLVGKLTQKH--YGLHRLVVQVNDSGQPS-QSTTTLVHVFVNESVSNATAI 802
+D +G + ++ K + LV++V D GQP ST TLV V+ +V
Sbjct: 630 RMDWRTGELRTARRVPAKRDPQRPYELVIEVRDHGQPPLSSTATLVVQLVDGAVEPQGGG 689
Query: 803 DSQIARS-LHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVMARYC-RSK 860
S S H ++ G+ S + L++++ + G ++ I ++ ++V+A C + K
Sbjct: 690 GSGGGGSGEHQRPSRSGGGETSLD-----LTLILIIALGSVSFIFLLAMIVLAVRCQKEK 744
Query: 861 NKNGYEAGKKDHEDFFTPQQHDKSK---KPKKDKKNKKSKQPLYSSIVTVEASK-PNGQR 916
N Y D S + + +K K SK S I+ V++S P+
Sbjct: 745 KLNIYTCLASDCCLCCCCCGGGGSTCCGRQARARKKKLSK----SDIMLVQSSNVPSNPA 800
Query: 917 YDSVNEKLSDSPSMGRYRSVNGGPGSPDLARHYKSSSPLPTVQLHPQS---------PTA 967
+ E +GG GS H+ + + V L P+S P +
Sbjct: 801 QVPIEE--------------SGGFGS-----HHHNQNYCYQVCLTPESAKTDLMFLKPCS 841
Query: 968 GKKHQAVQDLPPANTFVGAGDNISIGSDHCSEYSCQTNNKYSKQPFRRVTFSVVSQPQDP 1027
+ + P G D + S S +T ++ ++ + +V +P+
Sbjct: 842 PSRSTDTEHNPCGAIVTGYTDQQPDIISNGSILSNETKHQRAELSY------LVDRPRRV 895
Query: 1028 HQGSLQSCYDSGLEESETPSSKSSSGPRLGALPLPEDNYERTTPDGSVDSRPLPDVALTG 1087
+ + Q E++ SSK S D+ + + + + + L
Sbjct: 896 NSSAFQ--------EADIVSSKDSGHG---------DSEQGDSDHDATNRAQSAGMDLFS 938
Query: 1088 KCTRECDEYGHSDSCWMP 1105
CT EC GHSD CWMP
Sbjct: 939 NCTEECKALGHSDRCWMP 956
>gi|14589914 protocadherin 10 isoform 2 precursor [Homo sapiens]
Length = 896
Score = 309 bits (792), Expect = 9e-84
Identities = 230/711 (32%), Positives = 334/711 (46%), Gaps = 77/711 (10%)
Query: 19 LLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGI----VTGSGEVTFSLESGSEY 74
LL L + L Y + EE +GN+A DLG+ ++ G T S + Y
Sbjct: 5 LLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVP-NSRTPY 63
Query: 75 LKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVL 134
L ++ TG L +E+ IDRE++ C+ C L EV + P ++LF+ ++ VL
Sbjct: 64 LDLNLETGVLYVNEK-IDREQI--CKQ---SPSCVLHLEVFLENP----LELFQVEIEVL 113
Query: 135 DINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYEL---------LQE 185
DINDN P+FP P LT+ + E+ GT + L +A D D G N + YE+ +Q
Sbjct: 114 DINDNPPSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQT 173
Query: 186 PGGGGSGGESRRAGAADS----------APYPGGGGNGASGGGSGGSKRRLDASEGGGGT 235
G G E D GGGG G GG GG GG G
Sbjct: 174 QGDGNRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGG---------GGAGL 224
Query: 236 NPGGRSSVFELQVADTPDGEKQPQLIVKGVYEADLAENSAPGTPILQLRAADLDVGVNGQ 295
P + + L D + VY L ENS PGT ++QL A D D G NG+
Sbjct: 225 PPQQQRTGTALLTIRVLDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGE 284
Query: 296 IEYVFGA-ATESVRRLLRLDETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATV 354
+ Y F + + R L L +G L V +D EE + V A+D G V
Sbjct: 285 VVYSFSSHISPRARELFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKV 344
Query: 355 VLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCT 414
++ + D NDN P I + V+E T +AL V+DRD ENG V C
Sbjct: 345 LVRVLDANDNAPEISFSTVKEA--------VSEGAAPGTVVALFSVTDRDSEENGQVQCE 396
Query: 415 VVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSL 474
++GDVPF+LK + K Y + T PLD EA + + +VA D G P+LS++ S+
Sbjct: 397 LLGDVPFRLKSSF-------KNYYTIVTEAPLDREAGDSYTLTVVARDRGEPALSTSKSI 449
Query: 475 IVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSL------D 528
V+V D NDN P F Q V +VY ENN+PG + V ATD D G NA++AYS+
Sbjct: 450 QVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGANAQLAYSILECQIQG 509
Query: 529 SSVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIP-VLQGSTTVIVQVADKND 587
SV +I+ ++G + D EQ + F+V A+D G P L G+ TV + + D+ND
Sbjct: 510 MSVFTYVSINSENGYLYALRSFDYEQLKDFSFQVEARDAGSPQALAGNATVNILIVDQND 569
Query: 588 NDPKFMQDV-------FTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENN--NIF 638
N P + + + + +P + V +DAD G NA ++ I N N+F
Sbjct: 570 NAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTRVAAVDADDGENARLTYSIVRGNEMNLF 629
Query: 639 SIENDTGTIYST--MSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMD 687
++ TG + + + R+ Q Y ++ D G PP S+TAT+ + ++D
Sbjct: 630 RMDWRTGELRTARRVPAKRDPQRPYELVIEVRDHGQPPLSSTATLVVQLVD 680
Score = 225 bits (574), Expect = 2e-58
Identities = 192/661 (29%), Positives = 307/661 (46%), Gaps = 72/661 (10%)
Query: 246 LQVADTPDGEKQPQLIVKGVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATE 305
L + D P +P L V +++E++ PGT A D DVG N +Y
Sbjct: 113 LDINDNPPSFPEPDLTV------EISESATPGTRFPLESAFDPDVGTNSLRDYEI----- 161
Query: 306 SVRRLLRLD-ETSG------WLSVLHRIDREEVNQLRFTVMARDRG-------------- 344
+ LD +T G L + +DRE+ R+ + A D G
Sbjct: 162 TPNSYFSLDVQTQGDGNRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGG 221
Query: 345 -----QPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQ 399
Q +T A + + + D NDNVP+ + ++ E+ T + +
Sbjct: 222 AGLPPQQQRTGTALLTIRVLDSNDNVPAFDQPVY--------TVSLPENSPPGTLVIQLN 273
Query: 400 VSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIV 459
+D D+G+NG VV + P + + + L S LDYE + + V +
Sbjct: 274 ATDPDEGQNG----EVVYSFSSHISPRARELFGLSPRTGRLEVSGELDYEESPVYQVYVQ 329
Query: 460 AVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGK 519
A D G ++ ++ ++V+V D NDN P S V+ E PG VA TD DS +
Sbjct: 330 AKDLGPNAVPAHCKVLVRVLDANDNAPEISFSTVKEAVSEGAAPGTVVALFSVTDRDSEE 389
Query: 520 NAEIAYSLDSSV-MGIFAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTV 578
N ++ L V + + + I+ LDRE D Y V A+D+G P L S ++
Sbjct: 390 NGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLDREAGDSYTLTVVARDRGEPALSTSKSI 449
Query: 579 IVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEE----N 634
VQV+D NDN P+F Q V+ YV EN P + + V+ D D+G NA+++ I E
Sbjct: 450 QVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGANAQLAYSILECQIQG 509
Query: 635 NNIF---SIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSA-TATVSLFVMDEND 690
++F SI ++ G +Y+ SFD E ++F+V+A D G P A ATV++ ++D+ND
Sbjct: 510 MSVFTYVSINSENGYLYALRSFDYEQLKDFSFQVEARDAGSPQALAGNATVNILIVDQND 569
Query: 691 NAPTVTLPK-----NISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLF 745
NAP + P + +LP S+ ++ V A D+DDG NA L YSIV GN LF
Sbjct: 570 NAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTRVAAVDADDGENARLTYSIVRGNEMNLF 629
Query: 746 EIDPTSGVVSLVGKLTQKH--YGLHRLVVQVNDSGQPS-QSTTTLVHVFVNESVSNATAI 802
+D +G + ++ K + LV++V D GQP ST TLV V+ +V
Sbjct: 630 RMDWRTGELRTARRVPAKRDPQRPYELVIEVRDHGQPPLSSTATLVVQLVDGAVEPQGGG 689
Query: 803 DSQIARS-LHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVMARYCRSKN 861
S S H ++ G+ S + L++++ + G ++ I ++ ++V+A C+ +
Sbjct: 690 GSGGGGSGEHQRPSRSGGGETSLD-----LTLILIIALGSVSFIFLLAMIVLAVRCQKEK 744
Query: 862 K 862
K
Sbjct: 745 K 745
>gi|14270505 protocadherin gamma subfamily B, 5 isoform 2 precursor
[Homo sapiens]
Length = 818
Score = 296 bits (758), Expect = 8e-80
Identities = 216/684 (31%), Positives = 322/684 (47%), Gaps = 56/684 (8%)
Query: 20 LLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGI-VTGSGEVTFSLESGSEYLKID 78
L LSL A + +RYR+ EE P +GN+A+DLG V + S Y +
Sbjct: 19 LFLLSLFCPALCEQIRYRIPEEMPKGSVVGNLATDLGFSVQELPTRKLRVSSEKPYFTVS 78
Query: 79 NLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDIND 138
+GEL S R +DRE++ + C L+FE P ++ + V + DIND
Sbjct: 79 AESGELLVSSR-LDREEI-----CGKKPACALEFEAVAENP----LNFYHVNVEIEDIND 128
Query: 139 NTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRA 198
+TP F L + E+ GT ++L A D D G N +++Y+L P E +
Sbjct: 129 HTPKFTQNSFELQISESAQPGTRFILEVAEDADIGLNSLQKYKLSLNPSFSLIIKEKQ-- 186
Query: 199 GAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQP 258
D + YP S RL + GG P ++ +QV D D P
Sbjct: 187 ---DGSKYPELALEKTLDREQQ-SYHRLVLTALDGGHPPLSGTTELRIQVTDANDN---P 239
Query: 259 QLIVKGVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSG 318
+ + VY L EN PGT +LQ+ A D D G+N +I Y F + + L+ SG
Sbjct: 240 PVFNRDVYRVSLRENVPPGTTVLQVSATDQDEGINSEITYSFYRTGQ----IFSLNSKSG 295
Query: 319 WLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPL 378
++ ++D EE + V RD G + TV +NI+DENDN P + +
Sbjct: 296 EITTQKKLDFEETKEYSMVVEGRDGGG--LVAQCTVEINIQDENDNSPEVTFHSL----- 348
Query: 379 KDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKY 438
+ + E+ + T IAL+++ D+D GENG V C + G+VPF++ +S K Y
Sbjct: 349 ---LEMILENAVPGTLIALIKIHDQDSGENGEVNCQLQGEVPFKIISSS-------KNSY 398
Query: 439 FLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFP 498
L T LD E T E+NV I A D G P LSS+ S+I+ + D NDN P+F Q+ V P
Sbjct: 399 KLVTDGTLDREQTPEYNVTITATDRGKPPLSSSISVILHIRDVNDNAPVFHQASYLVSVP 458
Query: 499 ENNIPGERVATVLATDADSGKNAEIAYSLDSS------VMGIFAIDPDSGDILVNTVLDR 552
ENN PG +A V A+D D G N +++YS+ +S + ++ SG + D
Sbjct: 459 ENNPPGASIAQVCASDLDLGLNGQVSYSIMASDLEPLALASYVSMSAQSGVVFAQRAFDY 518
Query: 553 EQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQ-------DVFTFYVKENL 605
EQ +E + A+D+G P L + ++ V V D+NDN P+ + V
Sbjct: 519 EQLRTFELTLQARDQGSPALSANVSLRVLVGDRNDNAPRVLYPALGPDGSALFDMVPRAA 578
Query: 606 QPNSPVGMVTVMDADKGRNAEMSLYIEENN--NIFSIENDTGTIYSTMSFDREHQTTYTF 663
+P V V +DAD G NA +S ++ + + +FS+ TG + + +
Sbjct: 579 EPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAARQRL 638
Query: 664 RVKAVDGGDPPRSATATVSLFVMD 687
V DGG PP SATAT+ L D
Sbjct: 639 LVAVRDGGQPPLSATATLHLVFAD 662
Score = 220 bits (561), Expect = 6e-57
Identities = 168/614 (27%), Positives = 286/614 (46%), Gaps = 53/614 (8%)
Query: 266 YEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGW--LSVL 323
+E ++E++ PGT + A D D+G+N +Y + + S + L++
Sbjct: 138 FELQISESAQPGTRFILEVAEDADIGLNSLQKYKLSLNPSFSLIIKEKQDGSKYPELALE 197
Query: 324 HRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVA 383
+DRE+ + R + A D G PP + + + + D NDN P R + R+ L+
Sbjct: 198 KTLDREQQSYHRLVLTALDGGHPPLSGTTELRIQVTDANDNPPVFN-RDVYRVSLR---- 252
Query: 384 NVAEDVLVDTPIALVQVSDRDQGENGVVTCTV--VGDVPFQLKPASDTEGDQNKKKYFLH 441
E+V T + V +D+D+G N +T + G + F L N K +
Sbjct: 253 ---ENVPPGTTVLQVSATDQDEGINSEITYSFYRTGQI-FSL----------NSKSGEIT 298
Query: 442 TSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPP-MFGQSVVEVYFPEN 500
T LD+E T+E+++V+ D G L + ++ + + D NDN P + S++E+ EN
Sbjct: 299 TQKKLDFEETKEYSMVVEGRDGGG--LVAQCTVEINIQDENDNSPEVTFHSLLEMIL-EN 355
Query: 501 NIPGERVATVLATDADSGKNAEIAYSLDSSV-MGIFAIDPDSGDILVNTVLDREQTDRYE 559
+PG +A + D DSG+N E+ L V I + +S ++ + LDREQT Y
Sbjct: 356 AVPGTLIALIKIHDQDSGENGEVNCQLQGEVPFKIISSSKNSYKLVTDGTLDREQTPEYN 415
Query: 560 FKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDA 619
+ A D+G P L S +VI+ + D NDN P F Q + V EN P + + V D
Sbjct: 416 VTITATDRGKPPLSSSISVILHIRDVNDNAPVFHQASYLVSVPENNPPGASIAQVCASDL 475
Query: 620 DKGRNAEMSLYIEENN-------NIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGD 672
D G N ++S I ++ + S+ +G +++ +FD E T+ ++A D G
Sbjct: 476 DLGLNGQVSYSIMASDLEPLALASYVSMSAQSGVVFAQRAFDYEQLRTFELTLQARDQGS 535
Query: 673 PPRSATATVSLFVMDENDNAPTVTLPK-----NISYTLLPPSSNVRTVVATVLATDSDDG 727
P SA ++ + V D NDNAP V P + + ++P ++ +V V+A D+D G
Sbjct: 536 PALSANVSLRVLVGDRNDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSG 595
Query: 728 INADLNYSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTL 787
NA L+Y ++ + LF + +G V L + RL+V V D GQP S T
Sbjct: 596 HNAWLSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATAT 655
Query: 788 VHVFVNESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILI 847
+H+ +S+ L + + DP E+ + +V+ + + +L
Sbjct: 656 LHLVFADSLQEV----------LPDITDRPVPSDPQAEL---QFYLVVALALISVLFLLA 702
Query: 848 ILIVVMARYCRSKN 861
+++ V R RS +
Sbjct: 703 VILAVALRLRRSSS 716
Score = 151 bits (382), Expect = 3e-36
Identities = 101/329 (30%), Positives = 160/329 (48%), Gaps = 9/329 (2%)
Query: 476 VKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGKNAEIAY--SLDSSVMG 533
V++ D ND+ P F Q+ E+ E+ PG R +A DAD G N+ Y SL+ S
Sbjct: 121 VEIEDINDHTPKFTQNSFELQISESAQPGTRFILEVAEDADIGLNSLQKYKLSLNPSFSL 180
Query: 534 IFAIDPDSG---DILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDP 590
I D ++ + LDREQ + + A D G P L G+T + +QV D NDN P
Sbjct: 181 IIKEKQDGSKYPELALEKTLDREQQSYHRLVLTALDGGHPPLSGTTELRIQVTDANDNPP 240
Query: 591 KFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYST 650
F +DV+ ++EN+ P + V V+ D D+G N+E++ IFS+ + +G I +
Sbjct: 241 VFNRDVYRVSLRENVPPGTTVLQVSATDQDEGINSEITYSFYRTGQIFSLNSKSGEITTQ 300
Query: 651 MSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSS 710
D E Y+ V+ DGG A TV + + DENDN+P VT + L ++
Sbjct: 301 KKLDFEETKEYSMVVEGRDGGG--LVAQCTVEINIQDENDNSPEVTFHSLLEMIL--ENA 356
Query: 711 NVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRL 770
T++A + D D G N ++N + G PFK+ S + G L ++ + +
Sbjct: 357 VPGTLIALIKIHDQDSGENGEVNCQLQGEVPFKIISSSKNSYKLVTDGTLDREQTPEYNV 416
Query: 771 VVQVNDSGQPSQSTTTLVHVFVNESVSNA 799
+ D G+P S++ V + + + NA
Sbjct: 417 TITATDRGKPPLSSSISVILHIRDVNDNA 445
>gi|11128031 protocadherin gamma subfamily B, 5 isoform 1 precursor
[Homo sapiens]
Length = 923
Score = 296 bits (758), Expect = 8e-80
Identities = 216/684 (31%), Positives = 322/684 (47%), Gaps = 56/684 (8%)
Query: 20 LLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGI-VTGSGEVTFSLESGSEYLKID 78
L LSL A + +RYR+ EE P +GN+A+DLG V + S Y +
Sbjct: 19 LFLLSLFCPALCEQIRYRIPEEMPKGSVVGNLATDLGFSVQELPTRKLRVSSEKPYFTVS 78
Query: 79 NLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDIND 138
+GEL S R +DRE++ + C L+FE P ++ + V + DIND
Sbjct: 79 AESGELLVSSR-LDREEI-----CGKKPACALEFEAVAENP----LNFYHVNVEIEDIND 128
Query: 139 NTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRA 198
+TP F L + E+ GT ++L A D D G N +++Y+L P E +
Sbjct: 129 HTPKFTQNSFELQISESAQPGTRFILEVAEDADIGLNSLQKYKLSLNPSFSLIIKEKQ-- 186
Query: 199 GAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQP 258
D + YP S RL + GG P ++ +QV D D P
Sbjct: 187 ---DGSKYPELALEKTLDREQQ-SYHRLVLTALDGGHPPLSGTTELRIQVTDANDN---P 239
Query: 259 QLIVKGVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSG 318
+ + VY L EN PGT +LQ+ A D D G+N +I Y F + + L+ SG
Sbjct: 240 PVFNRDVYRVSLRENVPPGTTVLQVSATDQDEGINSEITYSFYRTGQ----IFSLNSKSG 295
Query: 319 WLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPL 378
++ ++D EE + V RD G + TV +NI+DENDN P + +
Sbjct: 296 EITTQKKLDFEETKEYSMVVEGRDGGG--LVAQCTVEINIQDENDNSPEVTFHSL----- 348
Query: 379 KDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKY 438
+ + E+ + T IAL+++ D+D GENG V C + G+VPF++ +S K Y
Sbjct: 349 ---LEMILENAVPGTLIALIKIHDQDSGENGEVNCQLQGEVPFKIISSS-------KNSY 398
Query: 439 FLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFP 498
L T LD E T E+NV I A D G P LSS+ S+I+ + D NDN P+F Q+ V P
Sbjct: 399 KLVTDGTLDREQTPEYNVTITATDRGKPPLSSSISVILHIRDVNDNAPVFHQASYLVSVP 458
Query: 499 ENNIPGERVATVLATDADSGKNAEIAYSLDSS------VMGIFAIDPDSGDILVNTVLDR 552
ENN PG +A V A+D D G N +++YS+ +S + ++ SG + D
Sbjct: 459 ENNPPGASIAQVCASDLDLGLNGQVSYSIMASDLEPLALASYVSMSAQSGVVFAQRAFDY 518
Query: 553 EQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQ-------DVFTFYVKENL 605
EQ +E + A+D+G P L + ++ V V D+NDN P+ + V
Sbjct: 519 EQLRTFELTLQARDQGSPALSANVSLRVLVGDRNDNAPRVLYPALGPDGSALFDMVPRAA 578
Query: 606 QPNSPVGMVTVMDADKGRNAEMSLYIEENN--NIFSIENDTGTIYSTMSFDREHQTTYTF 663
+P V V +DAD G NA +S ++ + + +FS+ TG + + +
Sbjct: 579 EPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAARQRL 638
Query: 664 RVKAVDGGDPPRSATATVSLFVMD 687
V DGG PP SATAT+ L D
Sbjct: 639 LVAVRDGGQPPLSATATLHLVFAD 662
Score = 220 bits (561), Expect = 6e-57
Identities = 168/614 (27%), Positives = 286/614 (46%), Gaps = 53/614 (8%)
Query: 266 YEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGW--LSVL 323
+E ++E++ PGT + A D D+G+N +Y + + S + L++
Sbjct: 138 FELQISESAQPGTRFILEVAEDADIGLNSLQKYKLSLNPSFSLIIKEKQDGSKYPELALE 197
Query: 324 HRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVA 383
+DRE+ + R + A D G PP + + + + D NDN P R + R+ L+
Sbjct: 198 KTLDREQQSYHRLVLTALDGGHPPLSGTTELRIQVTDANDNPPVFN-RDVYRVSLR---- 252
Query: 384 NVAEDVLVDTPIALVQVSDRDQGENGVVTCTV--VGDVPFQLKPASDTEGDQNKKKYFLH 441
E+V T + V +D+D+G N +T + G + F L N K +
Sbjct: 253 ---ENVPPGTTVLQVSATDQDEGINSEITYSFYRTGQI-FSL----------NSKSGEIT 298
Query: 442 TSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPP-MFGQSVVEVYFPEN 500
T LD+E T+E+++V+ D G L + ++ + + D NDN P + S++E+ EN
Sbjct: 299 TQKKLDFEETKEYSMVVEGRDGGG--LVAQCTVEINIQDENDNSPEVTFHSLLEMIL-EN 355
Query: 501 NIPGERVATVLATDADSGKNAEIAYSLDSSV-MGIFAIDPDSGDILVNTVLDREQTDRYE 559
+PG +A + D DSG+N E+ L V I + +S ++ + LDREQT Y
Sbjct: 356 AVPGTLIALIKIHDQDSGENGEVNCQLQGEVPFKIISSSKNSYKLVTDGTLDREQTPEYN 415
Query: 560 FKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDA 619
+ A D+G P L S +VI+ + D NDN P F Q + V EN P + + V D
Sbjct: 416 VTITATDRGKPPLSSSISVILHIRDVNDNAPVFHQASYLVSVPENNPPGASIAQVCASDL 475
Query: 620 DKGRNAEMSLYIEENN-------NIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGD 672
D G N ++S I ++ + S+ +G +++ +FD E T+ ++A D G
Sbjct: 476 DLGLNGQVSYSIMASDLEPLALASYVSMSAQSGVVFAQRAFDYEQLRTFELTLQARDQGS 535
Query: 673 PPRSATATVSLFVMDENDNAPTVTLPK-----NISYTLLPPSSNVRTVVATVLATDSDDG 727
P SA ++ + V D NDNAP V P + + ++P ++ +V V+A D+D G
Sbjct: 536 PALSANVSLRVLVGDRNDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSG 595
Query: 728 INADLNYSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTL 787
NA L+Y ++ + LF + +G V L + RL+V V D GQP S T
Sbjct: 596 HNAWLSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATAT 655
Query: 788 VHVFVNESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILI 847
+H+ +S+ L + + DP E+ + +V+ + + +L
Sbjct: 656 LHLVFADSLQEV----------LPDITDRPVPSDPQAEL---QFYLVVALALISVLFLLA 702
Query: 848 ILIVVMARYCRSKN 861
+++ V R RS +
Sbjct: 703 VILAVALRLRRSSS 716
Score = 151 bits (382), Expect = 3e-36
Identities = 101/329 (30%), Positives = 160/329 (48%), Gaps = 9/329 (2%)
Query: 476 VKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGKNAEIAY--SLDSSVMG 533
V++ D ND+ P F Q+ E+ E+ PG R +A DAD G N+ Y SL+ S
Sbjct: 121 VEIEDINDHTPKFTQNSFELQISESAQPGTRFILEVAEDADIGLNSLQKYKLSLNPSFSL 180
Query: 534 IFAIDPDSG---DILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDP 590
I D ++ + LDREQ + + A D G P L G+T + +QV D NDN P
Sbjct: 181 IIKEKQDGSKYPELALEKTLDREQQSYHRLVLTALDGGHPPLSGTTELRIQVTDANDNPP 240
Query: 591 KFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYST 650
F +DV+ ++EN+ P + V V+ D D+G N+E++ IFS+ + +G I +
Sbjct: 241 VFNRDVYRVSLRENVPPGTTVLQVSATDQDEGINSEITYSFYRTGQIFSLNSKSGEITTQ 300
Query: 651 MSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSS 710
D E Y+ V+ DGG A TV + + DENDN+P VT + L ++
Sbjct: 301 KKLDFEETKEYSMVVEGRDGGG--LVAQCTVEINIQDENDNSPEVTFHSLLEMIL--ENA 356
Query: 711 NVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRL 770
T++A + D D G N ++N + G PFK+ S + G L ++ + +
Sbjct: 357 VPGTLIALIKIHDQDSGENGEVNCQLQGEVPFKIISSSKNSYKLVTDGTLDREQTPEYNV 416
Query: 771 VVQVNDSGQPSQSTTTLVHVFVNESVSNA 799
+ D G+P S++ V + + + NA
Sbjct: 417 TITATDRGKPPLSSSISVILHIRDVNDNA 445
>gi|14277685 protocadherin gamma subfamily C, 5 isoform 2 precursor
[Homo sapiens]
Length = 878
Score = 288 bits (736), Expect = 3e-77
Identities = 218/711 (30%), Positives = 327/711 (45%), Gaps = 59/711 (8%)
Query: 34 LRYRLAEEGPADVRIGNVASDLGIVTG---SGEVTFSLESGSEYLKIDNLTGELSTSERR 90
LRY + EE +GNVA DLG+ S + E Y + ++G L+ +++
Sbjct: 31 LRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYFSLSLMSGALAVNQK- 89
Query: 91 IDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDINDNTPTFPSPVLTL 150
IDRE L C L +V P ++L +V +LD+NDN+P+F +P +
Sbjct: 90 IDRESLCGAS-----TSCLLPVQVVTEHP----LELIRVEVEILDLNDNSPSFATPEREM 140
Query: 151 TVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYPGGG 210
+ E+ G + L +A D D G N + Y L S D P+P
Sbjct: 141 RISESAASGARFPLDSAQDPDVGTNTVSFYTL-----SPNSHFSLNVKTLKDGKPFPELV 195
Query: 211 GNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQPQLIVKGVYEADL 270
++ +L + GGT +++ + V D D Q V +
Sbjct: 196 LEQQLDR-EAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQ---SSVLRVGI 251
Query: 271 AENSAPGTPILQLRAADLDVGVNGQIEYVFGAAT-ESVRRLLRLDETSGWLSVLHRIDRE 329
EN+ GT +L+L A D D G NGQ++Y FG T E+VR L LD +SG + VL ID E
Sbjct: 252 PENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFE 311
Query: 330 EVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDV 389
E ARD+GQP + +++ D NDN P + + + V E
Sbjct: 312 ESRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLAN--------PVLEST 363
Query: 390 LVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYE 449
V T + L V DRD G NG V+ + D+PFQ+KP+ + Y L TS PLD E
Sbjct: 364 PVGTVVGLFNVRDRDSGRNGEVSLDISPDLPFQIKPSEN--------HYSLLTSQPLDRE 415
Query: 450 ATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVAT 509
AT + + ++A D+GSPSL + ++ + + D NDN P F Q + Y EN PG + T
Sbjct: 416 ATSHYIIELLASDAGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCT 475
Query: 510 VLATDADSGKNAEIAYSL-DSSVMGIFA-----IDPDSGDILVNTVLDREQTDRYEFKVN 563
V A+D D+G NA + YS+ + V G A ++P+ G I D E + V
Sbjct: 476 VAASDPDTGDNARLTYSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVG 535
Query: 564 AKDKGIPVLQGSTTVIVQVADKNDNDPKFM------QDVFTFYVKENLQPNSPVGMVTVM 617
+D G P L +T++ V V D+NDN P + + + + P S V VT +
Sbjct: 536 VRDSGSPPLHANTSLHVFVLDENDNAPAVLHPRPDWEHSAPQRLPRSAPPGSLVTKVTAV 595
Query: 618 DADKGRNAEMSLYIEENN---NIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPP 674
DAD G NA +S + + +F + TG + + + + T V D GDP
Sbjct: 596 DADAGHNAWLSYSLLPQSTAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPS 655
Query: 675 RSATATVSLFVMDENDNAPTVTLPKNISYTLLPPS-SNVRTVVATVLATDS 724
S+TATV L + DE+ +PK+ + + PP S++ + LAT S
Sbjct: 656 LSSTATVLLVLEDEDPE----EMPKSSDFLIHPPERSDLTLYLIVALATVS 702
Score = 199 bits (505), Expect = 2e-50
Identities = 171/555 (30%), Positives = 243/555 (43%), Gaps = 31/555 (5%)
Query: 262 VKGVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLS 321
V G + E S PGT + + A DL + + + +E R L SG L+
Sbjct: 27 VSGQLRYSVVEESEPGTLVGNV-AQDLGLKMTDLLSRRLQLGSEENGRYFSLSLMSGALA 85
Query: 322 VLHRIDREEV-NQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKD 380
V +IDRE + ++ + V + I D NDN PS +
Sbjct: 86 VNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPSFAT--------PE 137
Query: 381 GVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFL 440
++E L D D G N V T+ + F L + +G + L
Sbjct: 138 REMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPE---L 194
Query: 441 HTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPEN 500
LD EA +V+ AVD G+P+ S + V V D NDN P F SV+ V PEN
Sbjct: 195 VLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIPEN 254
Query: 501 NIPGERVATVLATDADSGKNAEIAYSL----DSSVMGIFAIDPDSGDILVNTVLDREQTD 556
G + + ATD D G N ++ YS +V +F +DP SG I V +D E++
Sbjct: 255 APIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEESR 314
Query: 557 RYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTV 616
YE A+D+G P ++G + V V D NDN P+ + V E+ + VG+ V
Sbjct: 315 FYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLFNV 374
Query: 617 MDADKGRNAEMSLYIEEN--NNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPP 674
D D GRN E+SL I + I EN ++ ++ DRE + Y + A D G P
Sbjct: 375 RDRDSGRNGEVSLDISPDLPFQIKPSENHY-SLLTSQPLDREATSHYIIELLASDAGSPS 433
Query: 675 RSATATVSLFVMDENDNAPTVTLPKNISYTL--LPPSSNVRTVVATVLATDSDDGINADL 732
T+ L + D NDNAP +Y L PP S ++ TV A+D D G NA L
Sbjct: 434 LHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGS----LLCTVAASDPDTGDNARL 489
Query: 733 NYSIVG----GNPFKLF-EIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTL 787
YSIVG G P F ++P G + + + ++VV V DSG P T
Sbjct: 490 TYSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTS 549
Query: 788 VHVFVNESVSNATAI 802
+HVFV + NA A+
Sbjct: 550 LHVFVLDENDNAPAV 564
Score = 193 bits (490), Expect = 9e-49
Identities = 169/629 (26%), Positives = 279/629 (44%), Gaps = 67/629 (10%)
Query: 267 EADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGW--LSVLH 324
E ++E++A G A D DVG N Y + + L + + L +
Sbjct: 139 EMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELVLEQ 198
Query: 325 RIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIE--IRKIGRIPLKDGV 382
++DRE + + + A D G P ++ + + + D NDN P+ + + ++G
Sbjct: 199 QLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVG-------- 250
Query: 383 ANVAEDVLVDTPIALVQVSDRDQGENGVV-------TCTVVGDVPFQLKPASDTEGDQNK 435
+ E+ + T + + +D D+G NG + T V ++ F L P+S
Sbjct: 251 --IPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNL-FGLDPSSGA------ 301
Query: 436 KKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEV 495
+H P+D+E +R + + A D G P++ + + V VGD NDN P + +
Sbjct: 302 ----IHVLGPIDFEESRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLAN 357
Query: 496 YFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSG--DILVNTVLDRE 553
E+ G V D DSG+N E+ SLD S F I P +L + LDRE
Sbjct: 358 PVLESTPVGTVVGLFNVRDRDSGRNGEV--SLDISPDLPFQIKPSENHYSLLTSQPLDRE 415
Query: 554 QTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGM 613
T Y ++ A D G P L T+ + ++D NDN P+F Q ++T Y+ EN P S +
Sbjct: 416 ATSHYIIELLASDAGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCT 475
Query: 614 VTVMDADKGRNAEMSLYIEEN-------NNIFSIENDTGTIYSTMSFDREHQTTYTFRVK 666
V D D G NA ++ I N ++ + + G I++ +FD E V
Sbjct: 476 VAASDPDTGDNARLTYSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVG 535
Query: 667 AVDGGDPPRSATATVSLFVMDENDNAPTVTLPK----NISYTLLPPSSNVRTVVATVLAT 722
D G PP A ++ +FV+DENDNAP V P+ + + LP S+ ++V V A
Sbjct: 536 VRDSGSPPLHANTSLHVFVLDENDNAPAVLHPRPDWEHSAPQRLPRSAPPGSLVTKVTAV 595
Query: 723 DSDDGINADLNYSIVGGNPFK-LFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPS 781
D+D G NA L+YS++ + LF + +G V L + ++VV V D+G PS
Sbjct: 596 DADAGHNAWLSYSLLPQSTAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPS 655
Query: 782 QSTTTLVHVFVNESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGI 841
S+T V + + + +P + D P +R + + ++ +
Sbjct: 656 LSSTATVLLVLEDEDPE------------EMPKSSDFLIHP-----PERSDLTLYLIVAL 698
Query: 842 MTVILIILI--VVMARYCRSKNKNGYEAG 868
TV L+ L+ ++ C N +G G
Sbjct: 699 ATVSLLSLVTFTFLSAKCLQGNADGDGGG 727
Score = 48.9 bits (115), Expect = 3e-05
Identities = 56/221 (25%), Positives = 91/221 (41%), Gaps = 16/221 (7%)
Query: 599 FYVKENLQPNSPVGMVTV---MDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDR 655
+ V E +P + VG V + + + L EEN FS+ +G + DR
Sbjct: 33 YSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYFSLSLMSGALAVNQKIDR 92
Query: 656 EH----QTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSN 711
E T+ V+ V + P V + ++D NDN+P+ P+ +S
Sbjct: 93 ESLCGASTSCLLPVQVVT--EHPLELIR-VEVEILDLNDNSPSFATPEREMRISESAASG 149
Query: 712 VRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGV----VSLVGKLTQKHYGL 767
R + + A D D G N Y++ + F L G + L +L ++
Sbjct: 150 ARFPLDS--AQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELVLEQQLDREAQAR 207
Query: 768 HRLVVQVNDSGQPSQSTTTLVHVFVNESVSNATAIDSQIAR 808
H+LV+ D G P++S TTL+ V V + NA S + R
Sbjct: 208 HQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLR 248
>gi|11128023 protocadherin gamma subfamily C, 5 isoform 1 precursor
[Homo sapiens]
Length = 944
Score = 288 bits (736), Expect = 3e-77
Identities = 218/711 (30%), Positives = 327/711 (45%), Gaps = 59/711 (8%)
Query: 34 LRYRLAEEGPADVRIGNVASDLGIVTG---SGEVTFSLESGSEYLKIDNLTGELSTSERR 90
LRY + EE +GNVA DLG+ S + E Y + ++G L+ +++
Sbjct: 31 LRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYFSLSLMSGALAVNQK- 89
Query: 91 IDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDINDNTPTFPSPVLTL 150
IDRE L C L +V P ++L +V +LD+NDN+P+F +P +
Sbjct: 90 IDRESLCGAS-----TSCLLPVQVVTEHP----LELIRVEVEILDLNDNSPSFATPEREM 140
Query: 151 TVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYPGGG 210
+ E+ G + L +A D D G N + Y L S D P+P
Sbjct: 141 RISESAASGARFPLDSAQDPDVGTNTVSFYTL-----SPNSHFSLNVKTLKDGKPFPELV 195
Query: 211 GNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQPQLIVKGVYEADL 270
++ +L + GGT +++ + V D D Q V +
Sbjct: 196 LEQQLDR-EAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQ---SSVLRVGI 251
Query: 271 AENSAPGTPILQLRAADLDVGVNGQIEYVFGAAT-ESVRRLLRLDETSGWLSVLHRIDRE 329
EN+ GT +L+L A D D G NGQ++Y FG T E+VR L LD +SG + VL ID E
Sbjct: 252 PENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFE 311
Query: 330 EVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDV 389
E ARD+GQP + +++ D NDN P + + + V E
Sbjct: 312 ESRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLAN--------PVLEST 363
Query: 390 LVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYE 449
V T + L V DRD G NG V+ + D+PFQ+KP+ + Y L TS PLD E
Sbjct: 364 PVGTVVGLFNVRDRDSGRNGEVSLDISPDLPFQIKPSEN--------HYSLLTSQPLDRE 415
Query: 450 ATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVAT 509
AT + + ++A D+GSPSL + ++ + + D NDN P F Q + Y EN PG + T
Sbjct: 416 ATSHYIIELLASDAGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCT 475
Query: 510 VLATDADSGKNAEIAYSL-DSSVMGIFA-----IDPDSGDILVNTVLDREQTDRYEFKVN 563
V A+D D+G NA + YS+ + V G A ++P+ G I D E + V
Sbjct: 476 VAASDPDTGDNARLTYSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVG 535
Query: 564 AKDKGIPVLQGSTTVIVQVADKNDNDPKFM------QDVFTFYVKENLQPNSPVGMVTVM 617
+D G P L +T++ V V D+NDN P + + + + P S V VT +
Sbjct: 536 VRDSGSPPLHANTSLHVFVLDENDNAPAVLHPRPDWEHSAPQRLPRSAPPGSLVTKVTAV 595
Query: 618 DADKGRNAEMSLYIEENN---NIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPP 674
DAD G NA +S + + +F + TG + + + + T V D GDP
Sbjct: 596 DADAGHNAWLSYSLLPQSTAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPS 655
Query: 675 RSATATVSLFVMDENDNAPTVTLPKNISYTLLPPS-SNVRTVVATVLATDS 724
S+TATV L + DE+ +PK+ + + PP S++ + LAT S
Sbjct: 656 LSSTATVLLVLEDEDPE----EMPKSSDFLIHPPERSDLTLYLIVALATVS 702
Score = 199 bits (505), Expect = 2e-50
Identities = 171/555 (30%), Positives = 243/555 (43%), Gaps = 31/555 (5%)
Query: 262 VKGVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLS 321
V G + E S PGT + + A DL + + + +E R L SG L+
Sbjct: 27 VSGQLRYSVVEESEPGTLVGNV-AQDLGLKMTDLLSRRLQLGSEENGRYFSLSLMSGALA 85
Query: 322 VLHRIDREEV-NQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKD 380
V +IDRE + ++ + V + I D NDN PS +
Sbjct: 86 VNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPSFAT--------PE 137
Query: 381 GVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFL 440
++E L D D G N V T+ + F L + +G + L
Sbjct: 138 REMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPE---L 194
Query: 441 HTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPEN 500
LD EA +V+ AVD G+P+ S + V V D NDN P F SV+ V PEN
Sbjct: 195 VLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIPEN 254
Query: 501 NIPGERVATVLATDADSGKNAEIAYSL----DSSVMGIFAIDPDSGDILVNTVLDREQTD 556
G + + ATD D G N ++ YS +V +F +DP SG I V +D E++
Sbjct: 255 APIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEESR 314
Query: 557 RYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTV 616
YE A+D+G P ++G + V V D NDN P+ + V E+ + VG+ V
Sbjct: 315 FYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLFNV 374
Query: 617 MDADKGRNAEMSLYIEEN--NNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPP 674
D D GRN E+SL I + I EN ++ ++ DRE + Y + A D G P
Sbjct: 375 RDRDSGRNGEVSLDISPDLPFQIKPSENHY-SLLTSQPLDREATSHYIIELLASDAGSPS 433
Query: 675 RSATATVSLFVMDENDNAPTVTLPKNISYTL--LPPSSNVRTVVATVLATDSDDGINADL 732
T+ L + D NDNAP +Y L PP S ++ TV A+D D G NA L
Sbjct: 434 LHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGS----LLCTVAASDPDTGDNARL 489
Query: 733 NYSIVG----GNPFKLF-EIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTL 787
YSIVG G P F ++P G + + + ++VV V DSG P T
Sbjct: 490 TYSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTS 549
Query: 788 VHVFVNESVSNATAI 802
+HVFV + NA A+
Sbjct: 550 LHVFVLDENDNAPAV 564
Score = 193 bits (490), Expect = 9e-49
Identities = 169/629 (26%), Positives = 279/629 (44%), Gaps = 67/629 (10%)
Query: 267 EADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGW--LSVLH 324
E ++E++A G A D DVG N Y + + L + + L +
Sbjct: 139 EMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELVLEQ 198
Query: 325 RIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIE--IRKIGRIPLKDGV 382
++DRE + + + A D G P ++ + + + D NDN P+ + + ++G
Sbjct: 199 QLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVG-------- 250
Query: 383 ANVAEDVLVDTPIALVQVSDRDQGENGVV-------TCTVVGDVPFQLKPASDTEGDQNK 435
+ E+ + T + + +D D+G NG + T V ++ F L P+S
Sbjct: 251 --IPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNL-FGLDPSSGA------ 301
Query: 436 KKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEV 495
+H P+D+E +R + + A D G P++ + + V VGD NDN P + +
Sbjct: 302 ----IHVLGPIDFEESRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLAN 357
Query: 496 YFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSG--DILVNTVLDRE 553
E+ G V D DSG+N E+ SLD S F I P +L + LDRE
Sbjct: 358 PVLESTPVGTVVGLFNVRDRDSGRNGEV--SLDISPDLPFQIKPSENHYSLLTSQPLDRE 415
Query: 554 QTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGM 613
T Y ++ A D G P L T+ + ++D NDN P+F Q ++T Y+ EN P S +
Sbjct: 416 ATSHYIIELLASDAGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCT 475
Query: 614 VTVMDADKGRNAEMSLYIEEN-------NNIFSIENDTGTIYSTMSFDREHQTTYTFRVK 666
V D D G NA ++ I N ++ + + G I++ +FD E V
Sbjct: 476 VAASDPDTGDNARLTYSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVG 535
Query: 667 AVDGGDPPRSATATVSLFVMDENDNAPTVTLPK----NISYTLLPPSSNVRTVVATVLAT 722
D G PP A ++ +FV+DENDNAP V P+ + + LP S+ ++V V A
Sbjct: 536 VRDSGSPPLHANTSLHVFVLDENDNAPAVLHPRPDWEHSAPQRLPRSAPPGSLVTKVTAV 595
Query: 723 DSDDGINADLNYSIVGGNPFK-LFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPS 781
D+D G NA L+YS++ + LF + +G V L + ++VV V D+G PS
Sbjct: 596 DADAGHNAWLSYSLLPQSTAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPS 655
Query: 782 QSTTTLVHVFVNESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGI 841
S+T V + + + +P + D P +R + + ++ +
Sbjct: 656 LSSTATVLLVLEDEDPE------------EMPKSSDFLIHP-----PERSDLTLYLIVAL 698
Query: 842 MTVILIILI--VVMARYCRSKNKNGYEAG 868
TV L+ L+ ++ C N +G G
Sbjct: 699 ATVSLLSLVTFTFLSAKCLQGNADGDGGG 727
Score = 48.9 bits (115), Expect = 3e-05
Identities = 56/221 (25%), Positives = 91/221 (41%), Gaps = 16/221 (7%)
Query: 599 FYVKENLQPNSPVGMVTV---MDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDR 655
+ V E +P + VG V + + + L EEN FS+ +G + DR
Sbjct: 33 YSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYFSLSLMSGALAVNQKIDR 92
Query: 656 EH----QTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSN 711
E T+ V+ V + P V + ++D NDN+P+ P+ +S
Sbjct: 93 ESLCGASTSCLLPVQVVT--EHPLELIR-VEVEILDLNDNSPSFATPEREMRISESAASG 149
Query: 712 VRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGV----VSLVGKLTQKHYGL 767
R + + A D D G N Y++ + F L G + L +L ++
Sbjct: 150 ARFPLDS--AQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELVLEQQLDREAQAR 207
Query: 768 HRLVVQVNDSGQPSQSTTTLVHVFVNESVSNATAIDSQIAR 808
H+LV+ D G P++S TTL+ V V + NA S + R
Sbjct: 208 HQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLR 248
>gi|14270499 protocadherin gamma subfamily B, 4 isoform 2 precursor
[Homo sapiens]
Length = 803
Score = 285 bits (728), Expect = 2e-76
Identities = 211/684 (30%), Positives = 324/684 (47%), Gaps = 54/684 (7%)
Query: 20 LLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGI-VTGSGEVTFSLESGSEYLKID 78
L LSL A + +RYR+ EE P +GN+A+DLG V + S Y +
Sbjct: 19 LFLLSLFCPALCEQIRYRIPEEMPKGSVVGNLATDLGFSVQELPTRKLRVSSEKPYFTVS 78
Query: 79 NLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDIND 138
+GEL S R +DRE++ + C L+FE P ++ + V + DIND
Sbjct: 79 AESGELLVSSR-LDREEI-----CGKKPACALEFEAVAENP----LNFYHVNVEIEDIND 128
Query: 139 NTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRA 198
+TP F L + E+ GT ++L +A D D G N ++ Y+L E
Sbjct: 129 HTPKFTQNSFELQISESAQPGTRFILGSAHDADIGSNTLQNYQLSPSDHFSLINKEK--- 185
Query: 199 GAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQP 258
+D + YP S L + G P SS ++ V T + P
Sbjct: 186 --SDGSKYPEMVLKTPLDREKQKSYH-LTLTALDFGAPP--LSSTAQIHVLVTDANDNAP 240
Query: 259 QLIVKGVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSG 318
+ + VY L+EN PGT +LQ+ A D D GVN +I + F A++ + L+ +G
Sbjct: 241 -VFSQDVYRVSLSENVYPGTTVLQVTATDQDEGVNAEITFSFSEASQITQ--FDLNSNTG 297
Query: 319 WLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPL 378
++VL+ +D EEV + + ARD G + TV + + DENDN P + + + +
Sbjct: 298 EITVLNTLDFEEVKEYSIVLEARDGGG--MIAQCTVEVEVIDENDNAPEVIFQSLPNL-- 353
Query: 379 KDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKY 438
+ ED + T IAL++V D+D NG VTC + GDVPF++ +S + Y
Sbjct: 354 ------IMEDAELGTHIALLKVRDKDSRHNGEVTCKLEGDVPFKILTSS-------RNTY 400
Query: 439 FLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFP 498
L T LD E E+N+ + A D G P LSS++S+ + +GD NDN P+F QS V+
Sbjct: 401 KLVTDAVLDREQNPEYNITVTATDRGKPPLSSSSSITLHIGDVNDNAPVFSQSSYIVHVA 460
Query: 499 ENNIPGERVATVLATDADSGKNAEIAYSLDSS------VMGIFAIDPDSGDILVNTVLDR 552
ENN PG ++ V A+D D G N +++Y + +S + +I +SG + D
Sbjct: 461 ENNPPGASISQVRASDPDLGPNGQVSYCIMASDLEQRELSSYVSISAESGVVFAQRAFDH 520
Query: 553 EQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQ-------DVFTFYVKENL 605
EQ +E + A+D+G P L + ++ V V D+NDN P+ + V
Sbjct: 521 EQLRAFELTLQARDQGSPALSANVSLRVLVDDRNDNAPRVLYPALGPDGSALFDMVPHAA 580
Query: 606 QPNSPVGMVTVMDADKGRNAEMSLYIEENN--NIFSIENDTGTIYSTMSFDREHQTTYTF 663
+P V V +DAD G NA +S ++ + + +FS+ TG + + +
Sbjct: 581 EPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAVRQRL 640
Query: 664 RVKAVDGGDPPRSATATVSLFVMD 687
V DGG PP SATAT+ L D
Sbjct: 641 LVAVRDGGQPPLSATATLHLVFAD 664
Score = 212 bits (539), Expect = 2e-54
Identities = 160/606 (26%), Positives = 277/606 (45%), Gaps = 55/606 (9%)
Query: 266 YEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGW----LS 321
+E ++E++ PGT + A D D+G N Y + L+ +++ G +
Sbjct: 138 FELQISESAQPGTRFILGSAHDADIGSNTLQNYQLSPSDHF--SLINKEKSDGSKYPEMV 195
Query: 322 VLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDG 381
+ +DRE+ T+ A D G PP + A + + + D NDN P + + R+ L
Sbjct: 196 LKTPLDREKQKSYHLTLTALDFGAPPLSSTAQIHVLVTDANDNAPVFS-QDVYRVSL--- 251
Query: 382 VANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASD-TEGDQNKKKYFL 440
+E+V T + V +D+D+G N +T F AS T+ D N +
Sbjct: 252 ----SENVYPGTTVLQVTATDQDEGVNAEIT--------FSFSEASQITQFDLNSNTGEI 299
Query: 441 HTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPP-MFGQSVVEVYFPE 499
LD+E +E+++V+ A D G + + ++ V+V D NDN P + QS+ + +
Sbjct: 300 TVLNTLDFEEVKEYSIVLEARDGGG--MIAQCTVEVEVIDENDNAPEVIFQSLPNLIMED 357
Query: 500 NNIPGERVATVLATDADSGKNAEIAYSLDSSV-MGIFAIDPDSGDILVNTVLDREQTDRY 558
+ G +A + D DS N E+ L+ V I ++ ++ + VLDREQ Y
Sbjct: 358 AEL-GTHIALLKVRDKDSRHNGEVTCKLEGDVPFKILTSSRNTYKLVTDAVLDREQNPEY 416
Query: 559 EFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMD 618
V A D+G P L S+++ + + D NDN P F Q + +V EN P + + V D
Sbjct: 417 NITVTATDRGKPPLSSSSSITLHIGDVNDNAPVFSQSSYIVHVAENNPPGASISQVRASD 476
Query: 619 ADKGRNAEMSLYI-------EENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGG 671
D G N ++S I E ++ SI ++G +++ +FD E + ++A D G
Sbjct: 477 PDLGPNGQVSYCIMASDLEQRELSSYVSISAESGVVFAQRAFDHEQLRAFELTLQARDQG 536
Query: 672 DPPRSATATVSLFVMDENDNAPTVTLPK-----NISYTLLPPSSNVRTVVATVLATDSDD 726
P SA ++ + V D NDNAP V P + + ++P ++ +V V+A D+D
Sbjct: 537 SPALSANVSLRVLVDDRNDNAPRVLYPALGPDGSALFDMVPHAAEPGYLVTKVVAVDADS 596
Query: 727 GINADLNYSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTT 786
G NA L+Y ++ + LF + +G V L + RL+V V D GQP S T
Sbjct: 597 GHNAWLSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAVRQRLLVAVRDGGQPPLSATA 656
Query: 787 LVHVFVNESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVIL 846
+H+ +S+ + DI P + L + V +++V+
Sbjct: 657 TLHLVFADSLQE---------------VLPDITDRPDPSDLQAELQFYLVVALALISVLF 701
Query: 847 IILIVV 852
++ +++
Sbjct: 702 LVAMIL 707
Score = 178 bits (452), Expect = 2e-44
Identities = 142/502 (28%), Positives = 224/502 (44%), Gaps = 38/502 (7%)
Query: 317 SGWLSVLHRIDREEVN------QLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEI 370
SG L V R+DREE+ L F +A + + V + I+D ND+ P
Sbjct: 81 SGELLVSSRLDREEICGKKPACALEFEAVAEN-----PLNFYHVNVEIEDINDHTPKFTQ 135
Query: 371 RKIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTE 430
++E T L D D G N + + F L ++
Sbjct: 136 NSFE--------LQISESAQPGTRFILGSAHDADIGSNTLQNYQLSPSDHFSLINKEKSD 187
Query: 431 GDQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQ 490
G + + TPLD E + +++ + A+D G+P LSS + V V D NDN P+F Q
Sbjct: 188 GSKYPEMVL---KTPLDREKQKSYHLTLTALDFGAPPLSSTAQIHVLVTDANDNAPVFSQ 244
Query: 491 SVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSL-DSSVMGIFAIDPDSGDILVNTV 549
V V EN PG V V ATD D G NAEI +S ++S + F ++ ++G+I V
Sbjct: 245 DVYRVSLSENVYPGTTVLQVTATDQDEGVNAEITFSFSEASQITQFDLNSNTGEITVLNT 304
Query: 550 LDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNS 609
LD E+ Y + A+D G + Q TV V+V D+NDN P+ + + E+ + +
Sbjct: 305 LDFEEVKEYSIVLEARDGGGMIAQ--CTVEVEVIDENDNAPEVIFQSLPNLIMEDAELGT 362
Query: 610 PVGMVTVMDADKGRNAEMSLYIEEN--NNIFSIENDTGTIYSTMSFDREHQTTYTFRVKA 667
+ ++ V D D N E++ +E + I + +T + + DRE Y V A
Sbjct: 363 HIALLKVRDKDSRHNGEVTCKLEGDVPFKILTSSRNTYKLVTDAVLDREQNPEYNITVTA 422
Query: 668 VDGGDPPRSATATVSLFVMDENDNAPTVTLPKNISYTL--LPPSSNVRTVVATVLATDSD 725
D G PP S++++++L + D NDNAP + I + PP ++ ++ V A+D D
Sbjct: 423 TDRGKPPLSSSSSITLHIGDVNDNAPVFSQSSYIVHVAENNPPGAS----ISQVRASDPD 478
Query: 726 DGINADLNYSIVGGN-----PFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQP 780
G N ++Y I+ + I SGVV + L +Q D G P
Sbjct: 479 LGPNGQVSYCIMASDLEQRELSSYVSISAESGVVFAQRAFDHEQLRAFELTLQARDQGSP 538
Query: 781 SQSTTTLVHVFVNESVSNATAI 802
+ S + V V++ NA +
Sbjct: 539 ALSANVSLRVLVDDRNDNAPRV 560
Score = 110 bits (274), Expect = 1e-23
Identities = 77/274 (28%), Positives = 134/274 (48%), Gaps = 19/274 (6%)
Query: 529 SSVMGIFAIDPDSGDILVNTVLDREQ------TDRYEFKVNAKDKGIPVLQGSTTVIVQV 582
SS F + +SG++LV++ LDRE+ EF+ A++ V V++
Sbjct: 69 SSEKPYFTVSAESGELLVSSRLDREEICGKKPACALEFEAVAENP-----LNFYHVNVEI 123
Query: 583 ADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENN--NIFSI 640
D ND+ PKF Q+ F + E+ QP + + + DAD G N + + ++ ++ +
Sbjct: 124 EDINDHTPKFTQNSFELQISESAQPGTRFILGSAHDADIGSNTLQNYQLSPSDHFSLINK 183
Query: 641 ENDTGTIYSTM----SFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVT 696
E G+ Y M DRE Q +Y + A+D G PP S+TA + + V D NDNAP +
Sbjct: 184 EKSDGSKYPEMVLKTPLDREKQKSYHLTLTALDFGAPPLSSTAQIHVLVTDANDNAPVFS 243
Query: 697 LPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSL 756
+++ L + T V V ATD D+G+NA++ +S + F+++ +G +++
Sbjct: 244 --QDVYRVSLSENVYPGTTVLQVTATDQDEGVNAEITFSFSEASQITQFDLNSNTGEITV 301
Query: 757 VGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHV 790
+ L + + +V++ D G T V V
Sbjct: 302 LNTLDFEEVKEYSIVLEARDGGGMIAQCTVEVEV 335
>gi|13470082 protocadherin gamma subfamily B, 4 isoform 1 precursor
[Homo sapiens]
Length = 923
Score = 285 bits (728), Expect = 2e-76
Identities = 211/684 (30%), Positives = 324/684 (47%), Gaps = 54/684 (7%)
Query: 20 LLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGI-VTGSGEVTFSLESGSEYLKID 78
L LSL A + +RYR+ EE P +GN+A+DLG V + S Y +
Sbjct: 19 LFLLSLFCPALCEQIRYRIPEEMPKGSVVGNLATDLGFSVQELPTRKLRVSSEKPYFTVS 78
Query: 79 NLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDIND 138
+GEL S R +DRE++ + C L+FE P ++ + V + DIND
Sbjct: 79 AESGELLVSSR-LDREEI-----CGKKPACALEFEAVAENP----LNFYHVNVEIEDIND 128
Query: 139 NTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRA 198
+TP F L + E+ GT ++L +A D D G N ++ Y+L E
Sbjct: 129 HTPKFTQNSFELQISESAQPGTRFILGSAHDADIGSNTLQNYQLSPSDHFSLINKEK--- 185
Query: 199 GAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQP 258
+D + YP S L + G P SS ++ V T + P
Sbjct: 186 --SDGSKYPEMVLKTPLDREKQKSYH-LTLTALDFGAPP--LSSTAQIHVLVTDANDNAP 240
Query: 259 QLIVKGVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSG 318
+ + VY L+EN PGT +LQ+ A D D GVN +I + F A++ + L+ +G
Sbjct: 241 -VFSQDVYRVSLSENVYPGTTVLQVTATDQDEGVNAEITFSFSEASQITQ--FDLNSNTG 297
Query: 319 WLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPL 378
++VL+ +D EEV + + ARD G + TV + + DENDN P + + + +
Sbjct: 298 EITVLNTLDFEEVKEYSIVLEARDGGG--MIAQCTVEVEVIDENDNAPEVIFQSLPNL-- 353
Query: 379 KDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKY 438
+ ED + T IAL++V D+D NG VTC + GDVPF++ +S + Y
Sbjct: 354 ------IMEDAELGTHIALLKVRDKDSRHNGEVTCKLEGDVPFKILTSS-------RNTY 400
Query: 439 FLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFP 498
L T LD E E+N+ + A D G P LSS++S+ + +GD NDN P+F QS V+
Sbjct: 401 KLVTDAVLDREQNPEYNITVTATDRGKPPLSSSSSITLHIGDVNDNAPVFSQSSYIVHVA 460
Query: 499 ENNIPGERVATVLATDADSGKNAEIAYSLDSS------VMGIFAIDPDSGDILVNTVLDR 552
ENN PG ++ V A+D D G N +++Y + +S + +I +SG + D
Sbjct: 461 ENNPPGASISQVRASDPDLGPNGQVSYCIMASDLEQRELSSYVSISAESGVVFAQRAFDH 520
Query: 553 EQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQ-------DVFTFYVKENL 605
EQ +E + A+D+G P L + ++ V V D+NDN P+ + V
Sbjct: 521 EQLRAFELTLQARDQGSPALSANVSLRVLVDDRNDNAPRVLYPALGPDGSALFDMVPHAA 580
Query: 606 QPNSPVGMVTVMDADKGRNAEMSLYIEENN--NIFSIENDTGTIYSTMSFDREHQTTYTF 663
+P V V +DAD G NA +S ++ + + +FS+ TG + + +
Sbjct: 581 EPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAVRQRL 640
Query: 664 RVKAVDGGDPPRSATATVSLFVMD 687
V DGG PP SATAT+ L D
Sbjct: 641 LVAVRDGGQPPLSATATLHLVFAD 664
Score = 212 bits (539), Expect = 2e-54
Identities = 160/606 (26%), Positives = 277/606 (45%), Gaps = 55/606 (9%)
Query: 266 YEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGW----LS 321
+E ++E++ PGT + A D D+G N Y + L+ +++ G +
Sbjct: 138 FELQISESAQPGTRFILGSAHDADIGSNTLQNYQLSPSDHF--SLINKEKSDGSKYPEMV 195
Query: 322 VLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDG 381
+ +DRE+ T+ A D G PP + A + + + D NDN P + + R+ L
Sbjct: 196 LKTPLDREKQKSYHLTLTALDFGAPPLSSTAQIHVLVTDANDNAPVFS-QDVYRVSL--- 251
Query: 382 VANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASD-TEGDQNKKKYFL 440
+E+V T + V +D+D+G N +T F AS T+ D N +
Sbjct: 252 ----SENVYPGTTVLQVTATDQDEGVNAEIT--------FSFSEASQITQFDLNSNTGEI 299
Query: 441 HTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPP-MFGQSVVEVYFPE 499
LD+E +E+++V+ A D G + + ++ V+V D NDN P + QS+ + +
Sbjct: 300 TVLNTLDFEEVKEYSIVLEARDGGG--MIAQCTVEVEVIDENDNAPEVIFQSLPNLIMED 357
Query: 500 NNIPGERVATVLATDADSGKNAEIAYSLDSSV-MGIFAIDPDSGDILVNTVLDREQTDRY 558
+ G +A + D DS N E+ L+ V I ++ ++ + VLDREQ Y
Sbjct: 358 AEL-GTHIALLKVRDKDSRHNGEVTCKLEGDVPFKILTSSRNTYKLVTDAVLDREQNPEY 416
Query: 559 EFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMD 618
V A D+G P L S+++ + + D NDN P F Q + +V EN P + + V D
Sbjct: 417 NITVTATDRGKPPLSSSSSITLHIGDVNDNAPVFSQSSYIVHVAENNPPGASISQVRASD 476
Query: 619 ADKGRNAEMSLYI-------EENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGG 671
D G N ++S I E ++ SI ++G +++ +FD E + ++A D G
Sbjct: 477 PDLGPNGQVSYCIMASDLEQRELSSYVSISAESGVVFAQRAFDHEQLRAFELTLQARDQG 536
Query: 672 DPPRSATATVSLFVMDENDNAPTVTLPK-----NISYTLLPPSSNVRTVVATVLATDSDD 726
P SA ++ + V D NDNAP V P + + ++P ++ +V V+A D+D
Sbjct: 537 SPALSANVSLRVLVDDRNDNAPRVLYPALGPDGSALFDMVPHAAEPGYLVTKVVAVDADS 596
Query: 727 GINADLNYSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTT 786
G NA L+Y ++ + LF + +G V L + RL+V V D GQP S T
Sbjct: 597 GHNAWLSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAVRQRLLVAVRDGGQPPLSATA 656
Query: 787 LVHVFVNESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVIL 846
+H+ +S+ + DI P + L + V +++V+
Sbjct: 657 TLHLVFADSLQE---------------VLPDITDRPDPSDLQAELQFYLVVALALISVLF 701
Query: 847 IILIVV 852
++ +++
Sbjct: 702 LVAMIL 707
Score = 178 bits (452), Expect = 2e-44
Identities = 142/502 (28%), Positives = 224/502 (44%), Gaps = 38/502 (7%)
Query: 317 SGWLSVLHRIDREEVN------QLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEI 370
SG L V R+DREE+ L F +A + + V + I+D ND+ P
Sbjct: 81 SGELLVSSRLDREEICGKKPACALEFEAVAEN-----PLNFYHVNVEIEDINDHTPKFTQ 135
Query: 371 RKIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTE 430
++E T L D D G N + + F L ++
Sbjct: 136 NSFE--------LQISESAQPGTRFILGSAHDADIGSNTLQNYQLSPSDHFSLINKEKSD 187
Query: 431 GDQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQ 490
G + + TPLD E + +++ + A+D G+P LSS + V V D NDN P+F Q
Sbjct: 188 GSKYPEMVL---KTPLDREKQKSYHLTLTALDFGAPPLSSTAQIHVLVTDANDNAPVFSQ 244
Query: 491 SVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSL-DSSVMGIFAIDPDSGDILVNTV 549
V V EN PG V V ATD D G NAEI +S ++S + F ++ ++G+I V
Sbjct: 245 DVYRVSLSENVYPGTTVLQVTATDQDEGVNAEITFSFSEASQITQFDLNSNTGEITVLNT 304
Query: 550 LDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNS 609
LD E+ Y + A+D G + Q TV V+V D+NDN P+ + + E+ + +
Sbjct: 305 LDFEEVKEYSIVLEARDGGGMIAQ--CTVEVEVIDENDNAPEVIFQSLPNLIMEDAELGT 362
Query: 610 PVGMVTVMDADKGRNAEMSLYIEEN--NNIFSIENDTGTIYSTMSFDREHQTTYTFRVKA 667
+ ++ V D D N E++ +E + I + +T + + DRE Y V A
Sbjct: 363 HIALLKVRDKDSRHNGEVTCKLEGDVPFKILTSSRNTYKLVTDAVLDREQNPEYNITVTA 422
Query: 668 VDGGDPPRSATATVSLFVMDENDNAPTVTLPKNISYTL--LPPSSNVRTVVATVLATDSD 725
D G PP S++++++L + D NDNAP + I + PP ++ ++ V A+D D
Sbjct: 423 TDRGKPPLSSSSSITLHIGDVNDNAPVFSQSSYIVHVAENNPPGAS----ISQVRASDPD 478
Query: 726 DGINADLNYSIVGGN-----PFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQP 780
G N ++Y I+ + I SGVV + L +Q D G P
Sbjct: 479 LGPNGQVSYCIMASDLEQRELSSYVSISAESGVVFAQRAFDHEQLRAFELTLQARDQGSP 538
Query: 781 SQSTTTLVHVFVNESVSNATAI 802
+ S + V V++ NA +
Sbjct: 539 ALSANVSLRVLVDDRNDNAPRV 560
Score = 110 bits (274), Expect = 1e-23
Identities = 77/274 (28%), Positives = 134/274 (48%), Gaps = 19/274 (6%)
Query: 529 SSVMGIFAIDPDSGDILVNTVLDREQ------TDRYEFKVNAKDKGIPVLQGSTTVIVQV 582
SS F + +SG++LV++ LDRE+ EF+ A++ V V++
Sbjct: 69 SSEKPYFTVSAESGELLVSSRLDREEICGKKPACALEFEAVAENP-----LNFYHVNVEI 123
Query: 583 ADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENN--NIFSI 640
D ND+ PKF Q+ F + E+ QP + + + DAD G N + + ++ ++ +
Sbjct: 124 EDINDHTPKFTQNSFELQISESAQPGTRFILGSAHDADIGSNTLQNYQLSPSDHFSLINK 183
Query: 641 ENDTGTIYSTM----SFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVT 696
E G+ Y M DRE Q +Y + A+D G PP S+TA + + V D NDNAP +
Sbjct: 184 EKSDGSKYPEMVLKTPLDREKQKSYHLTLTALDFGAPPLSSTAQIHVLVTDANDNAPVFS 243
Query: 697 LPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSL 756
+++ L + T V V ATD D+G+NA++ +S + F+++ +G +++
Sbjct: 244 --QDVYRVSLSENVYPGTTVLQVTATDQDEGVNAEITFSFSEASQITQFDLNSNTGEITV 301
Query: 757 VGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHV 790
+ L + + +V++ D G T V V
Sbjct: 302 LNTLDFEEVKEYSIVLEARDGGGMIAQCTVEVEV 335
>gi|11036656 protocadherin beta 7 precursor [Homo sapiens]
Length = 793
Score = 281 bits (720), Expect = 2e-75
Identities = 217/731 (29%), Positives = 337/731 (46%), Gaps = 95/731 (12%)
Query: 23 LSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGIVTGSGEVT-----FSLESGSEYLKI 77
L +S A A+ L RY +AEE + N+A DLG+ G GE+ + + L +
Sbjct: 21 LGMSWAGAEPL-RYFVAEETERGTFLTNLAKDLGL--GVGELRARGTRIVSDQNMQILLL 77
Query: 78 DNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDIN 137
+LTG+L +E+ +DRE+L C L F++ + P Q +F ++ V DIN
Sbjct: 78 SSLTGDLLLNEK-LDREEL-----CGPREPCVLPFQLLLEKPFQ----IFRAELWVRDIN 127
Query: 138 DNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYEL---------LQEPGG 188
D+ P F ++L + E+ G +LL +A D D G N + Y + + + G
Sbjct: 128 DHAPVFLDREISLKILESTTPGAAFLLESAQDSDVGTNSLSNYTISPNAYFHINVHDSGE 187
Query: 189 GGSGGESRRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQV 248
G E D P + L + GG+ P +++ + V
Sbjct: 188 GNIYPELVLNQVLDREEIP---------------EFSLTLTALDGGSPPRSGTALVRILV 232
Query: 249 ADTPDGEKQPQLIVKGVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVR 308
D D V+ +Y+ + ENS G+ ++ + A DLD G NG+I Y F ATE +
Sbjct: 233 LDVNDNAPD---FVRSLYKVQVPENSPVGSMVVSVSARDLDTGSNGEIAYAFSYATERIL 289
Query: 309 RLLRLDETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSI 368
+ +++ TSG L + ++D E + T+ A+D G + K TVV+++ D NDN P +
Sbjct: 290 KTFQINPTSGSLHLKAQLDYEAIQTYTLTIQAKDGGG--LSGKCTVVVDVTDINDNRPEL 347
Query: 369 EIRKIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASD 428
+ + + +AE+ +T +A+ ++ DRD G NG C++ DVPF LKP+ +
Sbjct: 348 LLSSL--------TSPIAENS-PETVVAVFRIRDRDSGNNGKTVCSIQDDVPFILKPSVE 398
Query: 429 TEGDQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMF 488
Y L T PLD E E+N+ I D G+P L + +++ V V D NDN P F
Sbjct: 399 NF-------YTLVTEKPLDRERNTEYNITITVTDLGTPRLKTEHNITVLVSDVNDNAPAF 451
Query: 489 GQSVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSS------VMGIFAIDPDSG 542
Q+ ++ ENN P + +V ATD DSG NA++ YSL S + + +I+ D+G
Sbjct: 452 TQTSYTLFVRENNSPALPIGSVSATDRDSGTNAQVIYSLLPSQDPHLPLASLVSINADNG 511
Query: 543 DILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVK 602
+ LD E +EF+V A D+G P L V V V D NDN P F Y
Sbjct: 512 HLFALRSLDYEALQAFEFRVGATDRGSPALSSEALVRVLVLDANDNSP------FVLYPL 565
Query: 603 EN------------LQPNSPVGMVTVMDADKGRNAEMS--LYIEENNNIFSIENDTGTIY 648
+N +P V V +D D G+NA +S L +F + G +
Sbjct: 566 QNSSAPCTEPLPRAAEPGYLVTKVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEVR 625
Query: 649 STMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLPKNISYTLLPP 708
+ V D G+PPRSATAT+ + ++D + P + LP+ P
Sbjct: 626 TARLLSERDAAKQRLVVLVKDNGEPPRSATATLHVLLVD-GFSQPYLRLPE-----AAPD 679
Query: 709 SSNVRTVVATV 719
+N TV V
Sbjct: 680 QANSLTVYLVV 690
Score = 219 bits (559), Expect = 9e-57
Identities = 180/610 (29%), Positives = 274/610 (44%), Gaps = 59/610 (9%)
Query: 270 LAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLS---VLHRI 326
+ E++ PG L A D DVG N Y + + + D G + VL+++
Sbjct: 142 ILESTTPGAAFLLESAQDSDVGTNSLSNYTI--SPNAYFHINVHDSGEGNIYPELVLNQV 199
Query: 327 -DREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANV 385
DREE+ + T+ A D G PP++ A V + + D NDN P +R + ++ V
Sbjct: 200 LDREEIPEFSLTLTALDGGSPPRSGTALVRILVLDVNDNAPDF-VRSLYKV-------QV 251
Query: 386 AEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVP-----FQLKPASDTEGDQNKKKYFL 440
E+ V + + V D D G NG + FQ+ P S + L
Sbjct: 252 PENSPVGSMVVSVSARDLDTGSNGEIAYAFSYATERILKTFQINPTSGS----------L 301
Query: 441 HTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPEN 500
H LDYEA + + + I A D G LS +++V V D NDN P S + EN
Sbjct: 302 HLKAQLDYEAIQTYTLTIQAKDGGG--LSGKCTVVVDVTDINDNRPELLLSSLTSPIAEN 359
Query: 501 NIPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTV-LDREQTDRYE 559
+ P VA D DSG N + S+ V I ++ LV LDRE+ Y
Sbjct: 360 S-PETVVAVFRIRDRDSGNNGKTVCSIQDDVPFILKPSVENFYTLVTEKPLDRERNTEYN 418
Query: 560 FKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDA 619
+ D G P L+ + V V+D NDN P F Q +T +V+EN P P+G V+ D
Sbjct: 419 ITITVTDLGTPRLKTEHNITVLVSDVNDNAPAFTQTSYTLFVRENNSPALPIGSVSATDR 478
Query: 620 DKGRNAEMSLYIEENNN-------IFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGD 672
D G NA++ + + + + SI D G +++ S D E + FRV A D G
Sbjct: 479 DSGTNAQVIYSLLPSQDPHLPLASLVSINADNGHLFALRSLDYEALQAFEFRVGATDRGS 538
Query: 673 PPRSATATVSLFVMDENDNAPTVTLPKNISYTL----LPPSSNVRTVVATVLATDSDDGI 728
P S+ A V + V+D NDN+P V P S LP ++ +V V+A D D G
Sbjct: 539 PALSSEALVRVLVLDANDNSPFVLYPLQNSSAPCTEPLPRAAEPGYLVTKVVAVDGDSGQ 598
Query: 729 NADLNYSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLV 788
NA L+Y ++ LF + +G V L+++ RLVV V D+G+P +S T +
Sbjct: 599 NAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKQRLVVLVKDNGEPPRSATATL 658
Query: 789 HVFVNESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILII 848
HV + +D L +P + A D + ++ + +V+ + + +L +
Sbjct: 659 HVLL---------VDGFSQPYLRLP---EAAPDQANSLT---VYLVVALASVSSLFLLSV 703
Query: 849 LIVVMARYCR 858
L+ V R CR
Sbjct: 704 LLFVAVRLCR 713
Score = 186 bits (471), Expect = 2e-46
Identities = 164/579 (28%), Positives = 254/579 (43%), Gaps = 45/579 (7%)
Query: 270 LAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLHRIDRE 329
+AE + GT + L A DL +GV ++ ++L L +G L + ++DRE
Sbjct: 35 VAEETERGTFLTNL-AKDLGLGVGELRARGTRIVSDQNMQILLLSSLTGDLLLNEKLDRE 93
Query: 330 EVNQLR------FTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVA 383
E+ R F ++ Q + + L ++D ND+ P R+I
Sbjct: 94 ELCGPREPCVLPFQLLLEKPFQIFRAE-----LWVRDINDHAPVFLDREIS--------L 140
Query: 384 NVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTS 443
+ E L D D G N + T+ + F + EG+ + L +
Sbjct: 141 KILESTTPGAAFLLESAQDSDVGTNSLSNYTISPNAYFHINVHDSGEGNIYPE---LVLN 197
Query: 444 TPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIP 503
LD E EF++ + A+D GSP S + + V D NDN P F +S+ +V PEN+
Sbjct: 198 QVLDREEIPEFSLTLTALDGGSPPRSGTALVRILVLDVNDNAPDFVRSLYKVQVPENSPV 257
Query: 504 GERVATVLATDADSGKNAEIAYSLD---SSVMGIFAIDPDSGDILVNTVLDREQTDRYEF 560
G V +V A D D+G N EIAY+ ++ F I+P SG + + LD E Y
Sbjct: 258 GSMVVSVSARDLDTGSNGEIAYAFSYATERILKTFQINPTSGSLHLKAQLDYEAIQTYTL 317
Query: 561 KVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDAD 620
+ AKD G L G TV+V V D NDN P+ + T + EN P + V + + D D
Sbjct: 318 TIQAKDGG--GLSGKCTVVVDVTDINDNRPELLLSSLTSPIAEN-SPETVVAVFRIRDRD 374
Query: 621 KGRNAEMSLYIEENNNIF---SIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSA 677
G N + I+++ S+EN T+ + DRE T Y + D G P
Sbjct: 375 SGNNGKTVCSIQDDVPFILKPSVEN-FYTLVTEKPLDRERNTEYNITITVTDLGTPRLKT 433
Query: 678 TATVSLFVMDENDNAPTVTLPKNISYTLLPPSSNVRTV-VATVLATDSDDGINADLNYSI 736
+++ V D NDNAP T SYTL +N + + +V ATD D G NA + YS+
Sbjct: 434 EHNITVLVSDVNDNAPAFT---QTSYTLFVRENNSPALPIGSVSATDRDSGTNAQVIYSL 490
Query: 737 VGGNP-----FKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVF 791
+ L I+ +G + + L + V D G P+ S+ LV V
Sbjct: 491 LPSQDPHLPLASLVSINADNGHLFALRSLDYEALQAFEFRVGATDRGSPALSSEALVRVL 550
Query: 792 VNESVSNATAIDSQIARSLHIPLTQDI--AGDPSYEISK 828
V ++ N+ + + S P T+ + A +P Y ++K
Sbjct: 551 VLDANDNSPFVLYPLQNS-SAPCTEPLPRAAEPGYLVTK 588
>gi|14270508 protocadherin gamma subfamily B, 7 isoform 2 precursor
[Homo sapiens]
Length = 808
Score = 281 bits (718), Expect = 3e-75
Identities = 210/687 (30%), Positives = 321/687 (46%), Gaps = 58/687 (8%)
Query: 19 LLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGIVT---GSGEVTFSLESGSEYL 75
LLLPL + +RY + EE +GN+A DLG+ + E+ S E +
Sbjct: 20 LLLPLFYPTLC--EPIRYSIPEELAKGSVVGNLAKDLGLSVLDVSARELRVSAEK--LHF 75
Query: 76 KIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLD 135
+D +G+L +R IDRE++ C+ + C L E V P +++F V++ D
Sbjct: 76 SVDAQSGDLLVKDR-IDREQI--CK---ERRRCELQLEAVVENP----LNIFHVIVVIED 125
Query: 136 INDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGES 195
+ND+ P F + L + E+ +G +L +A D D N + +Y+L P S E
Sbjct: 126 VNDHAPQFRKDEINLEISESVSLGMGTILESAEDPDISMNSLSKYQL--SPNEYFSLVEK 183
Query: 196 RRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGE 255
D YP + S L + GG P ++ + V D D
Sbjct: 184 DNP---DGGKYPELVLQKTLDRETQ-SAHHLVLTALDGGDPPRSGTAQIRILVIDANDN- 238
Query: 256 KQPQLIVKGVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDE 315
P + + VY L E+ PGT IL+++A D D G+N +I Y F + + + LD
Sbjct: 239 --PPVFSQDVYRVSLREDVPPGTSILRVKATDQDEGINSEITYSFFGVADKAQHVFSLDY 296
Query: 316 TSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGR 375
T+G + +D EEV + + A+DRG + + V++ + DENDN P I I +
Sbjct: 297 TTGNILTQQPLDFEEVERYTINIEAKDRGS--LSTRCKVIVEVVDENDNSPEIIITSLSD 354
Query: 376 IPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNK 435
++D V +AL + D+D GENG V C++ VPF++ +S+
Sbjct: 355 QIMEDSPPGVV--------VALFKTRDQDSGENGEVRCSLSRGVPFKIHSSSNNY----- 401
Query: 436 KKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEV 495
Y L T LD E T E+NV I A D G P LSS+ ++ + + D NDN P+FGQS V
Sbjct: 402 --YKLVTDEALDREQTPEYNVTIAATDRGKPPLSSSKTITLHITDVNDNAPVFGQSAYLV 459
Query: 496 YFPENNIPGERVATVLATDADSGKNAEIAYSLDSS------VMGIFAIDPDSGDILVNTV 549
+ PENN PG +A V A+D D G N ++YSL +S + ++ SG +
Sbjct: 460 HVPENNQPGASIAQVSASDPDFGLNGRVSYSLIASDLESRTLSSYVSVSAQSGVVFAQRA 519
Query: 550 LDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQ-------DVFTFYVK 602
D EQ +E + A+D+G P L + ++ V V D+NDN P+ + V
Sbjct: 520 FDHEQLRTFELTLQARDQGSPALSANVSLRVLVGDRNDNAPRVLYPALGPDGSALFDTVP 579
Query: 603 ENLQPNSPVGMVTVMDADKGRNAEMSLYIEENN--NIFSIENDTGTIYSTMSFDREHQTT 660
QP V V +DAD G NA +S ++ + + +FS+ TG + + +
Sbjct: 580 RAAQPGYLVTKVVAVDADSGHNAWLSYHVVQASEPGLFSLGLRTGEVRMVRALGDKDSVR 639
Query: 661 YTFRVKAVDGGDPPRSATATVSLFVMD 687
V DGG PP SATAT+ L D
Sbjct: 640 QRLLVAVRDGGQPPLSATATLHLVFAD 666
Score = 219 bits (558), Expect = 1e-56
Identities = 181/648 (27%), Positives = 293/648 (45%), Gaps = 59/648 (9%)
Query: 242 SVFELQVADTPDGEKQPQLIVKGVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFG 301
++F + V + PQ K +++E+ + G + A D D+ +N +Y
Sbjct: 115 NIFHVIVVIEDVNDHAPQFR-KDEINLEISESVSLGMGTILESAEDPDISMNSLSKYQL- 172
Query: 302 AATESVRRLLRLDETSGW----LSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLN 357
+ L+ D G L + +DRE + + A D G PP++ A + +
Sbjct: 173 -SPNEYFSLVEKDNPDGGKYPELVLQKTLDRETQSAHHLVLTALDGGDPPRSGTAQIRIL 231
Query: 358 IKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVG 417
+ D NDN P + + + R+ L+ EDV T I V+ +D+D+G N +T + G
Sbjct: 232 VIDANDN-PPVFSQDVYRVSLR-------EDVPPGTSILRVKATDQDEGINSEITYSFFG 283
Query: 418 --DVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLI 475
D + T G+ + T PLD+E + + I A D GS LS+ +I
Sbjct: 284 VADKAQHVFSLDYTTGN-------ILTQQPLDFEEVERYTINIEAKDRGS--LSTRCKVI 334
Query: 476 VKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIF 535
V+V D NDN P + + E++ PG VA D DSG+N E+ SL V F
Sbjct: 335 VEVVDENDNSPEIIITSLSDQIMEDSPPGVVVALFKTRDQDSGENGEVRCSLSRGVP--F 392
Query: 536 AIDPDSGD---ILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKF 592
I S + ++ + LDREQT Y + A D+G P L S T+ + + D NDN P F
Sbjct: 393 KIHSSSNNYYKLVTDEALDREQTPEYNVTIAATDRGKPPLSSSKTITLHITDVNDNAPVF 452
Query: 593 MQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENN-------NIFSIENDTG 645
Q + +V EN QP + + V+ D D G N +S + ++ + S+ +G
Sbjct: 453 GQSAYLVHVPENNQPGASIAQVSASDPDFGLNGRVSYSLIASDLESRTLSSYVSVSAQSG 512
Query: 646 TIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLPK-----N 700
+++ +FD E T+ ++A D G P SA ++ + V D NDNAP V P +
Sbjct: 513 VVFAQRAFDHEQLRTFELTLQARDQGSPALSANVSLRVLVGDRNDNAPRVLYPALGPDGS 572
Query: 701 ISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSLVGKL 760
+ +P ++ +V V+A D+D G NA L+Y +V + LF + +G V +V L
Sbjct: 573 ALFDTVPRAAQPGYLVTKVVAVDADSGHNAWLSYHVVQASEPGLFSLGLRTGEVRMVRAL 632
Query: 761 TQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVNESVSNATAIDSQIARSLHIPLTQDIAG 820
K RL+V V D GQP S T +H+ +S+ + D +
Sbjct: 633 GDKDSVRQRLLVAVRDGGQPPLSATATLHLVFADSLQE---------------VLPDFSD 677
Query: 821 DPSYEISKQRLSIVIGVVAGIMTVILIILIVVMARYCRSKNKNGYEAG 868
P+ S+ + + VVA + +L +L V++A R + AG
Sbjct: 678 HPTPSDSQAEMQFYL-VVALALISVLFLLAVILAIALRLRQSFSPTAG 724
Score = 187 bits (474), Expect = 7e-47
Identities = 149/556 (26%), Positives = 240/556 (43%), Gaps = 42/556 (7%)
Query: 258 PQLIVKGVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETS 317
P+ + KG +LA++ G +L + A +L V + +D S
Sbjct: 38 PEELAKGSVVGNLAKDL--GLSVLDVSARELRVSAE--------------KLHFSVDAQS 81
Query: 318 GWLSVLHRIDREEV-NQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRI 376
G L V RIDRE++ + R + + + V++ I+D ND+ P +I
Sbjct: 82 GDLLVKDRIDREQICKERRRCELQLEAVVENPLNIFHVIVVIEDVNDHAPQFRKDEIN-- 139
Query: 377 PLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKK 436
++E V + L D D N + + + F L + +G + +
Sbjct: 140 ------LEISESVSLGMGTILESAEDPDISMNSLSKYQLSPNEYFSLVEKDNPDGGKYPE 193
Query: 437 KYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVY 496
T LD E ++V+ A+D G P S + + V D NDNPP+F Q V V
Sbjct: 194 LVLQKT---LDRETQSAHHLVLTALDGGDPPRSGTAQIRILVIDANDNPPVFSQDVYRVS 250
Query: 497 FPENNIPGERVATVLATDADSGKNAEIAYS---LDSSVMGIFAIDPDSGDILVNTVLDRE 553
E+ PG + V ATD D G N+EI YS + +F++D +G+IL LD E
Sbjct: 251 LREDVPPGTSILRVKATDQDEGINSEITYSFFGVADKAQHVFSLDYTTGNILTQQPLDFE 310
Query: 554 QTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGM 613
+ +RY + AKD+G L VIV+V D+NDN P+ + + + E+ P V +
Sbjct: 311 EVERYTINIEAKDRG--SLSTRCKVIVEVVDENDNSPEIIITSLSDQIMEDSPPGVVVAL 368
Query: 614 VTVMDADKGRNAEMSLYIEEN--NNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGG 671
D D G N E+ + I S N+ + + + DRE Y + A D G
Sbjct: 369 FKTRDQDSGENGEVRCSLSRGVPFKIHSSSNNYYKLVTDEALDREQTPEYNVTIAATDRG 428
Query: 672 DPPRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINAD 731
PP S++ T++L + D NDNAP ++ +P ++ +A V A+D D G+N
Sbjct: 429 KPPLSSSKTITLHITDVNDNAP--VFGQSAYLVHVPENNQPGASIAQVSASDPDFGLNGR 486
Query: 732 LNYSIVGGN-----PFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTT 786
++YS++ + + SGVV + L +Q D G P+ S
Sbjct: 487 VSYSLIASDLESRTLSSYVSVSAQSGVVFAQRAFDHEQLRTFELTLQARDQGSPALSANV 546
Query: 787 LVHVFVNESVSNATAI 802
+ V V + NA +
Sbjct: 547 SLRVLVGDRNDNAPRV 562
>gi|11128027 protocadherin gamma subfamily B, 7 isoform 1 precursor
[Homo sapiens]
Length = 929
Score = 281 bits (718), Expect = 3e-75
Identities = 210/687 (30%), Positives = 321/687 (46%), Gaps = 58/687 (8%)
Query: 19 LLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGIVT---GSGEVTFSLESGSEYL 75
LLLPL + +RY + EE +GN+A DLG+ + E+ S E +
Sbjct: 20 LLLPLFYPTLC--EPIRYSIPEELAKGSVVGNLAKDLGLSVLDVSARELRVSAEK--LHF 75
Query: 76 KIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLD 135
+D +G+L +R IDRE++ C+ + C L E V P +++F V++ D
Sbjct: 76 SVDAQSGDLLVKDR-IDREQI--CK---ERRRCELQLEAVVENP----LNIFHVIVVIED 125
Query: 136 INDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGES 195
+ND+ P F + L + E+ +G +L +A D D N + +Y+L P S E
Sbjct: 126 VNDHAPQFRKDEINLEISESVSLGMGTILESAEDPDISMNSLSKYQL--SPNEYFSLVEK 183
Query: 196 RRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGE 255
D YP + S L + GG P ++ + V D D
Sbjct: 184 DNP---DGGKYPELVLQKTLDRETQ-SAHHLVLTALDGGDPPRSGTAQIRILVIDANDN- 238
Query: 256 KQPQLIVKGVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDE 315
P + + VY L E+ PGT IL+++A D D G+N +I Y F + + + LD
Sbjct: 239 --PPVFSQDVYRVSLREDVPPGTSILRVKATDQDEGINSEITYSFFGVADKAQHVFSLDY 296
Query: 316 TSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGR 375
T+G + +D EEV + + A+DRG + + V++ + DENDN P I I +
Sbjct: 297 TTGNILTQQPLDFEEVERYTINIEAKDRGS--LSTRCKVIVEVVDENDNSPEIIITSLSD 354
Query: 376 IPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNK 435
++D V +AL + D+D GENG V C++ VPF++ +S+
Sbjct: 355 QIMEDSPPGVV--------VALFKTRDQDSGENGEVRCSLSRGVPFKIHSSSNNY----- 401
Query: 436 KKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEV 495
Y L T LD E T E+NV I A D G P LSS+ ++ + + D NDN P+FGQS V
Sbjct: 402 --YKLVTDEALDREQTPEYNVTIAATDRGKPPLSSSKTITLHITDVNDNAPVFGQSAYLV 459
Query: 496 YFPENNIPGERVATVLATDADSGKNAEIAYSLDSS------VMGIFAIDPDSGDILVNTV 549
+ PENN PG +A V A+D D G N ++YSL +S + ++ SG +
Sbjct: 460 HVPENNQPGASIAQVSASDPDFGLNGRVSYSLIASDLESRTLSSYVSVSAQSGVVFAQRA 519
Query: 550 LDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQ-------DVFTFYVK 602
D EQ +E + A+D+G P L + ++ V V D+NDN P+ + V
Sbjct: 520 FDHEQLRTFELTLQARDQGSPALSANVSLRVLVGDRNDNAPRVLYPALGPDGSALFDTVP 579
Query: 603 ENLQPNSPVGMVTVMDADKGRNAEMSLYIEENN--NIFSIENDTGTIYSTMSFDREHQTT 660
QP V V +DAD G NA +S ++ + + +FS+ TG + + +
Sbjct: 580 RAAQPGYLVTKVVAVDADSGHNAWLSYHVVQASEPGLFSLGLRTGEVRMVRALGDKDSVR 639
Query: 661 YTFRVKAVDGGDPPRSATATVSLFVMD 687
V DGG PP SATAT+ L D
Sbjct: 640 QRLLVAVRDGGQPPLSATATLHLVFAD 666
Score = 219 bits (558), Expect = 1e-56
Identities = 181/648 (27%), Positives = 293/648 (45%), Gaps = 59/648 (9%)
Query: 242 SVFELQVADTPDGEKQPQLIVKGVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFG 301
++F + V + PQ K +++E+ + G + A D D+ +N +Y
Sbjct: 115 NIFHVIVVIEDVNDHAPQFR-KDEINLEISESVSLGMGTILESAEDPDISMNSLSKYQL- 172
Query: 302 AATESVRRLLRLDETSGW----LSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLN 357
+ L+ D G L + +DRE + + A D G PP++ A + +
Sbjct: 173 -SPNEYFSLVEKDNPDGGKYPELVLQKTLDRETQSAHHLVLTALDGGDPPRSGTAQIRIL 231
Query: 358 IKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVG 417
+ D NDN P + + + R+ L+ EDV T I V+ +D+D+G N +T + G
Sbjct: 232 VIDANDN-PPVFSQDVYRVSLR-------EDVPPGTSILRVKATDQDEGINSEITYSFFG 283
Query: 418 --DVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLI 475
D + T G+ + T PLD+E + + I A D GS LS+ +I
Sbjct: 284 VADKAQHVFSLDYTTGN-------ILTQQPLDFEEVERYTINIEAKDRGS--LSTRCKVI 334
Query: 476 VKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIF 535
V+V D NDN P + + E++ PG VA D DSG+N E+ SL V F
Sbjct: 335 VEVVDENDNSPEIIITSLSDQIMEDSPPGVVVALFKTRDQDSGENGEVRCSLSRGVP--F 392
Query: 536 AIDPDSGD---ILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKF 592
I S + ++ + LDREQT Y + A D+G P L S T+ + + D NDN P F
Sbjct: 393 KIHSSSNNYYKLVTDEALDREQTPEYNVTIAATDRGKPPLSSSKTITLHITDVNDNAPVF 452
Query: 593 MQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENN-------NIFSIENDTG 645
Q + +V EN QP + + V+ D D G N +S + ++ + S+ +G
Sbjct: 453 GQSAYLVHVPENNQPGASIAQVSASDPDFGLNGRVSYSLIASDLESRTLSSYVSVSAQSG 512
Query: 646 TIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLPK-----N 700
+++ +FD E T+ ++A D G P SA ++ + V D NDNAP V P +
Sbjct: 513 VVFAQRAFDHEQLRTFELTLQARDQGSPALSANVSLRVLVGDRNDNAPRVLYPALGPDGS 572
Query: 701 ISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSLVGKL 760
+ +P ++ +V V+A D+D G NA L+Y +V + LF + +G V +V L
Sbjct: 573 ALFDTVPRAAQPGYLVTKVVAVDADSGHNAWLSYHVVQASEPGLFSLGLRTGEVRMVRAL 632
Query: 761 TQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVNESVSNATAIDSQIARSLHIPLTQDIAG 820
K RL+V V D GQP S T +H+ +S+ + D +
Sbjct: 633 GDKDSVRQRLLVAVRDGGQPPLSATATLHLVFADSLQE---------------VLPDFSD 677
Query: 821 DPSYEISKQRLSIVIGVVAGIMTVILIILIVVMARYCRSKNKNGYEAG 868
P+ S+ + + VVA + +L +L V++A R + AG
Sbjct: 678 HPTPSDSQAEMQFYL-VVALALISVLFLLAVILAIALRLRQSFSPTAG 724
Score = 187 bits (474), Expect = 7e-47
Identities = 149/556 (26%), Positives = 240/556 (43%), Gaps = 42/556 (7%)
Query: 258 PQLIVKGVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETS 317
P+ + KG +LA++ G +L + A +L V + +D S
Sbjct: 38 PEELAKGSVVGNLAKDL--GLSVLDVSARELRVSAE--------------KLHFSVDAQS 81
Query: 318 GWLSVLHRIDREEV-NQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRI 376
G L V RIDRE++ + R + + + V++ I+D ND+ P +I
Sbjct: 82 GDLLVKDRIDREQICKERRRCELQLEAVVENPLNIFHVIVVIEDVNDHAPQFRKDEIN-- 139
Query: 377 PLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKK 436
++E V + L D D N + + + F L + +G + +
Sbjct: 140 ------LEISESVSLGMGTILESAEDPDISMNSLSKYQLSPNEYFSLVEKDNPDGGKYPE 193
Query: 437 KYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVY 496
T LD E ++V+ A+D G P S + + V D NDNPP+F Q V V
Sbjct: 194 LVLQKT---LDRETQSAHHLVLTALDGGDPPRSGTAQIRILVIDANDNPPVFSQDVYRVS 250
Query: 497 FPENNIPGERVATVLATDADSGKNAEIAYS---LDSSVMGIFAIDPDSGDILVNTVLDRE 553
E+ PG + V ATD D G N+EI YS + +F++D +G+IL LD E
Sbjct: 251 LREDVPPGTSILRVKATDQDEGINSEITYSFFGVADKAQHVFSLDYTTGNILTQQPLDFE 310
Query: 554 QTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGM 613
+ +RY + AKD+G L VIV+V D+NDN P+ + + + E+ P V +
Sbjct: 311 EVERYTINIEAKDRG--SLSTRCKVIVEVVDENDNSPEIIITSLSDQIMEDSPPGVVVAL 368
Query: 614 VTVMDADKGRNAEMSLYIEEN--NNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGG 671
D D G N E+ + I S N+ + + + DRE Y + A D G
Sbjct: 369 FKTRDQDSGENGEVRCSLSRGVPFKIHSSSNNYYKLVTDEALDREQTPEYNVTIAATDRG 428
Query: 672 DPPRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINAD 731
PP S++ T++L + D NDNAP ++ +P ++ +A V A+D D G+N
Sbjct: 429 KPPLSSSKTITLHITDVNDNAP--VFGQSAYLVHVPENNQPGASIAQVSASDPDFGLNGR 486
Query: 732 LNYSIVGGN-----PFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTT 786
++YS++ + + SGVV + L +Q D G P+ S
Sbjct: 487 VSYSLIASDLESRTLSSYVSVSAQSGVVFAQRAFDHEQLRTFELTLQARDQGSPALSANV 546
Query: 787 LVHVFVNESVSNATAI 802
+ V V + NA +
Sbjct: 547 SLRVLVGDRNDNAPRV 562
>gi|11128029 protocadherin gamma subfamily B, 6 isoform 1 precursor
[Homo sapiens]
Length = 930
Score = 280 bits (716), Expect = 6e-75
Identities = 214/704 (30%), Positives = 324/704 (46%), Gaps = 88/704 (12%)
Query: 19 LLLPLSLSL--AAAKQLLRYRLAEEGPADVRIGNVASDLGI-VTGSGEVTFSLESGSEYL 75
+L PL L L + +RY + EE +GN+A DLG+ V + + +
Sbjct: 16 VLFPLLLPLFYPTLSEPIRYSIPEELAKGSVVGNLAKDLGLSVLDVSARKLRVSAEKLHF 75
Query: 76 KIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLD 135
+D +G+L + RIDRE++ C+ + C L E V P +++F V++ D
Sbjct: 76 SVDAESGDLLV-KNRIDREQI--CK---ERRRCELQLEAVVENP----LNIFHVIVVIED 125
Query: 136 INDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGES 195
+ND+ P F + L + E+ GT L ATD D N I+ Y++
Sbjct: 126 VNDHAPQFDKKEIHLEIFESASAGTRLSLDPATDPDININSIKDYKI------------- 172
Query: 196 RRAGAADSAPYPGGGGNGASGGGSGGS---KRRLDASEG----------GGGTNPGGRSS 242
+S PY S GG ++ LD E GG P ++
Sbjct: 173 ------NSNPYFSLMVRVNSDGGKYPELSLEKLLDREEQRSHSLILTALDGGDPPRSATA 226
Query: 243 VFELQVADTPDGEKQPQLIVKGVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGA 302
E+ V DT D P + + Y L+EN PG+P+LQ+ A D D GVN +I Y F +
Sbjct: 227 HIEISVKDTNDN---PPVFSRDEYRISLSENLPPGSPVLQVTATDQDEGVNAEINYYFRS 283
Query: 303 ATESVRRLLRLDETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDEN 362
+S + + LDE +G + D E+V + V A+D G + + V++ I DEN
Sbjct: 284 TAQSTKHMFSLDEKTGMIKNNQSFDFEDVERYTMEVEAKDGGG--LSTQCKVIIEILDEN 341
Query: 363 DNVPSIEIRKIGRIPLKDGVANVAEDVLVDTP----IALVQVSDRDQGENGVVTCTVVGD 418
DN P I I ++++ +L ++P +AL + D D G NG V C + D
Sbjct: 342 DNSPEIII------------TSLSDQILENSPPGMVVALFKTRDLDFGGNGEVRCNIETD 389
Query: 419 VPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKV 478
+PF++ +S+ Y L T LD E T E+NV IVA D G P LSS+ S+ + V
Sbjct: 390 IPFKIYSSSNNY-------YKLVTDGALDREQTPEYNVTIVATDRGKPPLSSSRSITLYV 442
Query: 479 GDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSS------VM 532
D NDN P+F Q+ V+ ENN PG +A V A+D D G N I+YS+ +S V
Sbjct: 443 ADINDNAPVFDQTSYVVHVAENNPPGASIAQVSASDPDLGLNGHISYSIVASDLEPLAVS 502
Query: 533 GIFAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKF 592
++ SG + D EQ + + A+D G P L + ++ V V D+NDN P+
Sbjct: 503 SYVSVSAQSGVVFAQRAFDHEQLRAFALTLQARDHGSPTLSANVSLRVLVGDRNDNAPRV 562
Query: 593 MQ-------DVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENN--NIFSIEND 643
+ F V + +P V V +DAD G NA +S ++ + + +FS+
Sbjct: 563 LYPALGPDGSAFFDMVPRSAEPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGLFSLGLR 622
Query: 644 TGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMD 687
TG + + + V DGG PP SATAT+ L D
Sbjct: 623 TGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLVFAD 666
Score = 206 bits (525), Expect = 8e-53
Identities = 158/629 (25%), Positives = 288/629 (45%), Gaps = 52/629 (8%)
Query: 242 SVFELQVADTPDGEKQPQLIVKGVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFG 301
++F + V + PQ K ++ ++ E+++ GT + A D D+ +N +Y
Sbjct: 115 NIFHVIVVIEDVNDHAPQFDKKEIH-LEIFESASAGTRLSLDPATDPDININSIKDYKIN 173
Query: 302 AATESVRRLLRLDETSGW---LSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNI 358
+ ++R++ G LS+ +DREE + A D G PP++ A + +++
Sbjct: 174 S-NPYFSLMVRVNSDGGKYPELSLEKLLDREEQRSHSLILTALDGGDPPRSATAHIEISV 232
Query: 359 KDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGD 418
KD NDN P + R RI L +E++ +P+ V +D+D+G N +
Sbjct: 233 KDTNDN-PPVFSRDEYRISL-------SENLPPGSPVLQVTATDQDEGVNAEINY----- 279
Query: 419 VPFQLKPASDTEG--DQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIV 476
+ A T+ ++K + + D+E + + + A D G LS+ +I+
Sbjct: 280 --YFRSTAQSTKHMFSLDEKTGMIKNNQSFDFEDVERYTMEVEAKDGGG--LSTQCKVII 335
Query: 477 KVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSV-MGIF 535
++ D NDN P + + EN+ PG VA D D G N E+ ++++ + I+
Sbjct: 336 EILDENDNSPEIIITSLSDQILENSPPGMVVALFKTRDLDFGGNGEVRCNIETDIPFKIY 395
Query: 536 AIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQD 595
+ + ++ + LDREQT Y + A D+G P L S ++ + VAD NDN P F Q
Sbjct: 396 SSSNNYYKLVTDGALDREQTPEYNVTIVATDRGKPPLSSSRSITLYVADINDNAPVFDQT 455
Query: 596 VFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENN-------NIFSIENDTGTIY 648
+ +V EN P + + V+ D D G N +S I ++ + S+ +G ++
Sbjct: 456 SYVVHVAENNPPGASIAQVSASDPDLGLNGHISYSIVASDLEPLAVSSYVSVSAQSGVVF 515
Query: 649 STMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLPK-----NISY 703
+ +FD E + ++A D G P SA ++ + V D NDNAP V P + +
Sbjct: 516 AQRAFDHEQLRAFALTLQARDHGSPTLSANVSLRVLVGDRNDNAPRVLYPALGPDGSAFF 575
Query: 704 TLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSLVGKLTQK 763
++P S+ +V V+A D+D G NA L+Y ++ + LF + +G V L +
Sbjct: 576 DMVPRSAEPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARALGDR 635
Query: 764 HYGLHRLVVQVNDSGQPSQSTTTLVHVFVNESVSNATAIDSQIARSLHIPLTQDIAGDPS 823
RL+V V D GQP S T +H+ +++ + D++ P
Sbjct: 636 DAARQRLLVAVRDGGQPPLSATATLHLVFADNLQE---------------ILPDLSDRPV 680
Query: 824 YEISKQRLSIVIGVVAGIMTVILIILIVV 852
+ L + V +++V+ ++ +++
Sbjct: 681 LSDPQAELQFYLVVALALISVLFLLAVIL 709
Score = 192 bits (489), Expect = 1e-48
Identities = 146/503 (29%), Positives = 230/503 (45%), Gaps = 30/503 (5%)
Query: 313 LDETSGWLSVLHRIDREEV-NQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIR 371
+D SG L V +RIDRE++ + R + + + V++ I+D ND+ P + +
Sbjct: 77 VDAESGDLLVKNRIDREQICKERRRCELQLEAVVENPLNIFHVIVVIEDVNDHAPQFDKK 136
Query: 372 KIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEG 431
+I + E T ++L +D D N + + + F L +++G
Sbjct: 137 EIH--------LEIFESASAGTRLSLDPATDPDININSIKDYKINSNPYFSLMVRVNSDG 188
Query: 432 DQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQS 491
+ + L LD E R ++++ A+D G P S+ + + V DTNDNPP+F +
Sbjct: 189 GKYPE---LSLEKLLDREEQRSHSLILTALDGGDPPRSATAHIEISVKDTNDNPPVFSRD 245
Query: 492 VVEVYFPENNIPGERVATVLATDADSGKNAEIAY---SLDSSVMGIFAIDPDSGDILVNT 548
+ EN PG V V ATD D G NAEI Y S S +F++D +G I N
Sbjct: 246 EYRISLSENLPPGSPVLQVTATDQDEGVNAEINYYFRSTAQSTKHMFSLDEKTGMIKNNQ 305
Query: 549 VLDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPN 608
D E +RY +V AKD G L VI+++ D+NDN P+ + + + EN P
Sbjct: 306 SFDFEDVERYTMEVEAKDGG--GLSTQCKVIIEILDENDNSPEIIITSLSDQILENSPPG 363
Query: 609 SPVGMVTVMDADKGRNAEMSLYIEEN--NNIFSIENDTGTIYSTMSFDREHQTTYTFRVK 666
V + D D G N E+ IE + I+S N+ + + + DRE Y +
Sbjct: 364 MVVALFKTRDLDFGGNGEVRCNIETDIPFKIYSSSNNYYKLVTDGALDREQTPEYNVTIV 423
Query: 667 AVDGGDPPRSATATVSLFVMDENDNAPTVTLPKNISYTL--LPPSSNVRTVVATVLATDS 724
A D G PP S++ +++L+V D NDNAP + + PP ++ +A V A+D
Sbjct: 424 ATDRGKPPLSSSRSITLYVADINDNAPVFDQTSYVVHVAENNPPGAS----IAQVSASDP 479
Query: 725 DDGINADLNYSIVGGNPFKL-----FEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQ 779
D G+N ++YSIV + L + SGVV + L +Q D G
Sbjct: 480 DLGLNGHISYSIVASDLEPLAVSSYVSVSAQSGVVFAQRAFDHEQLRAFALTLQARDHGS 539
Query: 780 PSQSTTTLVHVFVNESVSNATAI 802
P+ S + V V + NA +
Sbjct: 540 PTLSANVSLRVLVGDRNDNAPRV 562
Score = 98.6 bits (244), Expect = 3e-20
Identities = 80/277 (28%), Positives = 131/277 (47%), Gaps = 35/277 (12%)
Query: 535 FAIDPDSGDILVNTVLDREQ----TDRYEFKVNA-KDKGIPVLQGSTTVIVQVADKNDND 589
F++D +SGD+LV +DREQ R E ++ A + + + VIV + D ND+
Sbjct: 75 FSVDAESGDLLVKNRIDREQICKERRRCELQLEAVVENPLNIFH----VIVVIEDVNDHA 130
Query: 590 PKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENNNIFSI---ENDTGT 646
P+F + + E+ + + + D D N+ + Y +N FS+ N G
Sbjct: 131 PQFDKKEIHLEIFESASAGTRLSLDPATDPDININS-IKDYKINSNPYFSLMVRVNSDGG 189
Query: 647 IYSTMS----FDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPT-------V 695
Y +S DRE Q +++ + A+DGGDPPRSATA + + V D NDN P +
Sbjct: 190 KYPELSLEKLLDREEQRSHSLILTALDGGDPPRSATAHIEISVKDTNDNPPVFSRDEYRI 249
Query: 696 TLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSI--VGGNPFKLFEIDPTSGV 753
+L +N LPP S V V ATD D+G+NA++NY + +F +D +G+
Sbjct: 250 SLSEN-----LPPGS----PVLQVTATDQDEGVNAEINYYFRSTAQSTKHMFSLDEKTGM 300
Query: 754 VSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHV 790
+ + + + V+ D G S ++ +
Sbjct: 301 IKNNQSFDFEDVERYTMEVEAKDGGGLSTQCKVIIEI 337
>gi|14270502 protocadherin gamma subfamily B, 6 isoform 2 precursor
[Homo sapiens]
Length = 820
Score = 280 bits (716), Expect = 6e-75
Identities = 214/704 (30%), Positives = 324/704 (46%), Gaps = 88/704 (12%)
Query: 19 LLLPLSLSL--AAAKQLLRYRLAEEGPADVRIGNVASDLGI-VTGSGEVTFSLESGSEYL 75
+L PL L L + +RY + EE +GN+A DLG+ V + + +
Sbjct: 16 VLFPLLLPLFYPTLSEPIRYSIPEELAKGSVVGNLAKDLGLSVLDVSARKLRVSAEKLHF 75
Query: 76 KIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLD 135
+D +G+L + RIDRE++ C+ + C L E V P +++F V++ D
Sbjct: 76 SVDAESGDLLV-KNRIDREQI--CK---ERRRCELQLEAVVENP----LNIFHVIVVIED 125
Query: 136 INDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGES 195
+ND+ P F + L + E+ GT L ATD D N I+ Y++
Sbjct: 126 VNDHAPQFDKKEIHLEIFESASAGTRLSLDPATDPDININSIKDYKI------------- 172
Query: 196 RRAGAADSAPYPGGGGNGASGGGSGGS---KRRLDASEG----------GGGTNPGGRSS 242
+S PY S GG ++ LD E GG P ++
Sbjct: 173 ------NSNPYFSLMVRVNSDGGKYPELSLEKLLDREEQRSHSLILTALDGGDPPRSATA 226
Query: 243 VFELQVADTPDGEKQPQLIVKGVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGA 302
E+ V DT D P + + Y L+EN PG+P+LQ+ A D D GVN +I Y F +
Sbjct: 227 HIEISVKDTNDN---PPVFSRDEYRISLSENLPPGSPVLQVTATDQDEGVNAEINYYFRS 283
Query: 303 ATESVRRLLRLDETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDEN 362
+S + + LDE +G + D E+V + V A+D G + + V++ I DEN
Sbjct: 284 TAQSTKHMFSLDEKTGMIKNNQSFDFEDVERYTMEVEAKDGGG--LSTQCKVIIEILDEN 341
Query: 363 DNVPSIEIRKIGRIPLKDGVANVAEDVLVDTP----IALVQVSDRDQGENGVVTCTVVGD 418
DN P I I ++++ +L ++P +AL + D D G NG V C + D
Sbjct: 342 DNSPEIII------------TSLSDQILENSPPGMVVALFKTRDLDFGGNGEVRCNIETD 389
Query: 419 VPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKV 478
+PF++ +S+ Y L T LD E T E+NV IVA D G P LSS+ S+ + V
Sbjct: 390 IPFKIYSSSNNY-------YKLVTDGALDREQTPEYNVTIVATDRGKPPLSSSRSITLYV 442
Query: 479 GDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSS------VM 532
D NDN P+F Q+ V+ ENN PG +A V A+D D G N I+YS+ +S V
Sbjct: 443 ADINDNAPVFDQTSYVVHVAENNPPGASIAQVSASDPDLGLNGHISYSIVASDLEPLAVS 502
Query: 533 GIFAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKF 592
++ SG + D EQ + + A+D G P L + ++ V V D+NDN P+
Sbjct: 503 SYVSVSAQSGVVFAQRAFDHEQLRAFALTLQARDHGSPTLSANVSLRVLVGDRNDNAPRV 562
Query: 593 MQ-------DVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENN--NIFSIEND 643
+ F V + +P V V +DAD G NA +S ++ + + +FS+
Sbjct: 563 LYPALGPDGSAFFDMVPRSAEPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGLFSLGLR 622
Query: 644 TGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMD 687
TG + + + V DGG PP SATAT+ L D
Sbjct: 623 TGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLVFAD 666
Score = 206 bits (525), Expect = 8e-53
Identities = 158/629 (25%), Positives = 288/629 (45%), Gaps = 52/629 (8%)
Query: 242 SVFELQVADTPDGEKQPQLIVKGVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFG 301
++F + V + PQ K ++ ++ E+++ GT + A D D+ +N +Y
Sbjct: 115 NIFHVIVVIEDVNDHAPQFDKKEIH-LEIFESASAGTRLSLDPATDPDININSIKDYKIN 173
Query: 302 AATESVRRLLRLDETSGW---LSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNI 358
+ ++R++ G LS+ +DREE + A D G PP++ A + +++
Sbjct: 174 S-NPYFSLMVRVNSDGGKYPELSLEKLLDREEQRSHSLILTALDGGDPPRSATAHIEISV 232
Query: 359 KDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGD 418
KD NDN P + R RI L +E++ +P+ V +D+D+G N +
Sbjct: 233 KDTNDN-PPVFSRDEYRISL-------SENLPPGSPVLQVTATDQDEGVNAEINY----- 279
Query: 419 VPFQLKPASDTEG--DQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIV 476
+ A T+ ++K + + D+E + + + A D G LS+ +I+
Sbjct: 280 --YFRSTAQSTKHMFSLDEKTGMIKNNQSFDFEDVERYTMEVEAKDGGG--LSTQCKVII 335
Query: 477 KVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSV-MGIF 535
++ D NDN P + + EN+ PG VA D D G N E+ ++++ + I+
Sbjct: 336 EILDENDNSPEIIITSLSDQILENSPPGMVVALFKTRDLDFGGNGEVRCNIETDIPFKIY 395
Query: 536 AIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQD 595
+ + ++ + LDREQT Y + A D+G P L S ++ + VAD NDN P F Q
Sbjct: 396 SSSNNYYKLVTDGALDREQTPEYNVTIVATDRGKPPLSSSRSITLYVADINDNAPVFDQT 455
Query: 596 VFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENN-------NIFSIENDTGTIY 648
+ +V EN P + + V+ D D G N +S I ++ + S+ +G ++
Sbjct: 456 SYVVHVAENNPPGASIAQVSASDPDLGLNGHISYSIVASDLEPLAVSSYVSVSAQSGVVF 515
Query: 649 STMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLPK-----NISY 703
+ +FD E + ++A D G P SA ++ + V D NDNAP V P + +
Sbjct: 516 AQRAFDHEQLRAFALTLQARDHGSPTLSANVSLRVLVGDRNDNAPRVLYPALGPDGSAFF 575
Query: 704 TLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSLVGKLTQK 763
++P S+ +V V+A D+D G NA L+Y ++ + LF + +G V L +
Sbjct: 576 DMVPRSAEPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARALGDR 635
Query: 764 HYGLHRLVVQVNDSGQPSQSTTTLVHVFVNESVSNATAIDSQIARSLHIPLTQDIAGDPS 823
RL+V V D GQP S T +H+ +++ + D++ P
Sbjct: 636 DAARQRLLVAVRDGGQPPLSATATLHLVFADNLQE---------------ILPDLSDRPV 680
Query: 824 YEISKQRLSIVIGVVAGIMTVILIILIVV 852
+ L + V +++V+ ++ +++
Sbjct: 681 LSDPQAELQFYLVVALALISVLFLLAVIL 709
Score = 192 bits (489), Expect = 1e-48
Identities = 146/503 (29%), Positives = 230/503 (45%), Gaps = 30/503 (5%)
Query: 313 LDETSGWLSVLHRIDREEV-NQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIR 371
+D SG L V +RIDRE++ + R + + + V++ I+D ND+ P + +
Sbjct: 77 VDAESGDLLVKNRIDREQICKERRRCELQLEAVVENPLNIFHVIVVIEDVNDHAPQFDKK 136
Query: 372 KIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEG 431
+I + E T ++L +D D N + + + F L +++G
Sbjct: 137 EIH--------LEIFESASAGTRLSLDPATDPDININSIKDYKINSNPYFSLMVRVNSDG 188
Query: 432 DQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQS 491
+ + L LD E R ++++ A+D G P S+ + + V DTNDNPP+F +
Sbjct: 189 GKYPE---LSLEKLLDREEQRSHSLILTALDGGDPPRSATAHIEISVKDTNDNPPVFSRD 245
Query: 492 VVEVYFPENNIPGERVATVLATDADSGKNAEIAY---SLDSSVMGIFAIDPDSGDILVNT 548
+ EN PG V V ATD D G NAEI Y S S +F++D +G I N
Sbjct: 246 EYRISLSENLPPGSPVLQVTATDQDEGVNAEINYYFRSTAQSTKHMFSLDEKTGMIKNNQ 305
Query: 549 VLDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPN 608
D E +RY +V AKD G L VI+++ D+NDN P+ + + + EN P
Sbjct: 306 SFDFEDVERYTMEVEAKDGG--GLSTQCKVIIEILDENDNSPEIIITSLSDQILENSPPG 363
Query: 609 SPVGMVTVMDADKGRNAEMSLYIEEN--NNIFSIENDTGTIYSTMSFDREHQTTYTFRVK 666
V + D D G N E+ IE + I+S N+ + + + DRE Y +
Sbjct: 364 MVVALFKTRDLDFGGNGEVRCNIETDIPFKIYSSSNNYYKLVTDGALDREQTPEYNVTIV 423
Query: 667 AVDGGDPPRSATATVSLFVMDENDNAPTVTLPKNISYTL--LPPSSNVRTVVATVLATDS 724
A D G PP S++ +++L+V D NDNAP + + PP ++ +A V A+D
Sbjct: 424 ATDRGKPPLSSSRSITLYVADINDNAPVFDQTSYVVHVAENNPPGAS----IAQVSASDP 479
Query: 725 DDGINADLNYSIVGGNPFKL-----FEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQ 779
D G+N ++YSIV + L + SGVV + L +Q D G
Sbjct: 480 DLGLNGHISYSIVASDLEPLAVSSYVSVSAQSGVVFAQRAFDHEQLRAFALTLQARDHGS 539
Query: 780 PSQSTTTLVHVFVNESVSNATAI 802
P+ S + V V + NA +
Sbjct: 540 PTLSANVSLRVLVGDRNDNAPRV 562
Score = 98.6 bits (244), Expect = 3e-20
Identities = 80/277 (28%), Positives = 131/277 (47%), Gaps = 35/277 (12%)
Query: 535 FAIDPDSGDILVNTVLDREQ----TDRYEFKVNA-KDKGIPVLQGSTTVIVQVADKNDND 589
F++D +SGD+LV +DREQ R E ++ A + + + VIV + D ND+
Sbjct: 75 FSVDAESGDLLVKNRIDREQICKERRRCELQLEAVVENPLNIFH----VIVVIEDVNDHA 130
Query: 590 PKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENNNIFSI---ENDTGT 646
P+F + + E+ + + + D D N+ + Y +N FS+ N G
Sbjct: 131 PQFDKKEIHLEIFESASAGTRLSLDPATDPDININS-IKDYKINSNPYFSLMVRVNSDGG 189
Query: 647 IYSTMS----FDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPT-------V 695
Y +S DRE Q +++ + A+DGGDPPRSATA + + V D NDN P +
Sbjct: 190 KYPELSLEKLLDREEQRSHSLILTALDGGDPPRSATAHIEISVKDTNDNPPVFSRDEYRI 249
Query: 696 TLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSI--VGGNPFKLFEIDPTSGV 753
+L +N LPP S V V ATD D+G+NA++NY + +F +D +G+
Sbjct: 250 SLSEN-----LPPGS----PVLQVTATDQDEGVNAEINYYFRSTAQSTKHMFSLDEKTGM 300
Query: 754 VSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHV 790
+ + + + V+ D G S ++ +
Sbjct: 301 IKNNQSFDFEDVERYTMEVEAKDGGGLSTQCKVIIEI 337
>gi|9256602 protocadherin beta 10 precursor [Homo sapiens]
Length = 800
Score = 279 bits (713), Expect = 1e-74
Identities = 208/683 (30%), Positives = 320/683 (46%), Gaps = 57/683 (8%)
Query: 35 RYRLAEEGPADVRIGNVASDLGIVTGS----GEVTFSLESGSEYLKIDNLTGELSTSERR 90
RY + EE + N+A DLG+ G G S + +YL +D+ TG L T+E+
Sbjct: 32 RYSVTEETEKGSFVVNLAKDLGLAEGELAARGTRVVS-DDNKQYLLLDSHTGNLLTNEK- 89
Query: 91 IDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDINDNTPTFPSPVLTL 150
+DREKL + C L F++ + P Q ++ ++ V DIND+ P F L
Sbjct: 90 LDREKL-----CGPKEPCMLYFQILMDDPFQ----IYRAELRVRDINDHAPVFQDKETVL 140
Query: 151 TVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYPGGG 210
+ EN GT + L A D D G NGI+ Y + S +G + YP
Sbjct: 141 KISENTAEGTAFRLERAQDPDGGLNGIQNYTI-----SPNSFFHINISGGDEGMIYPELV 195
Query: 211 GNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQPQLIVKGVYEADL 270
+ A G + GG + G S+V + V D D Q + +YE
Sbjct: 196 LDKALDREEQGELSLTLTALDGGSPSRSGTSTV-RIVVLDVNDNAPQ---FAQALYETQA 251
Query: 271 AENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLHRIDREE 330
ENS G I+++ A D+D GVN ++ Y F A+E++R +++ SG + + +D E
Sbjct: 252 PENSPIGFLIVKVWAEDVDSGVNAEVSYSFFDASENIRTTFQINPFSGEIFLRELLDYEL 311
Query: 331 VNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVL 390
VN + + A D G + + V++ + D NDN P + + +VAE+
Sbjct: 312 VNSYKINIQAMDGGG--LSARCRVLVEVLDTNDNPPELIVSSFSN--------SVAENS- 360
Query: 391 VDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEA 450
+TP+A+ +++DRD GENG + C + ++PF LKP+ + Y L T LD E
Sbjct: 361 PETPLAVFKINDRDSGENGKMVCYIQENLPFLLKPSVENF-------YILITEGALDREI 413
Query: 451 TREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATV 510
E+N+ I D G+P L + +++ V V D NDN P F Q+ ++ ENN P + +V
Sbjct: 414 RAEYNITITVTDLGTPRLKTEHNITVLVSDVNDNAPAFTQTSYTLFVRENNSPALHIGSV 473
Query: 511 LATDADSGKNAEIAYSL------DSSVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVNA 564
ATD DSG NA++ YSL + + +I+ D+G + LD E +EF+V A
Sbjct: 474 SATDRDSGTNAQVTYSLLPPQDPHLPLASLVSINADNGHLFALRSLDYEALQAFEFRVGA 533
Query: 565 KDKGIPVLQGSTTVIVQVADKNDNDPKFMQDV------FTFYVKENLQPNSPVGMVTVMD 618
D+G P L V V V D NDN P + + T V +P V V +D
Sbjct: 534 TDRGSPALSREALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVD 593
Query: 619 ADKGRNAEMS--LYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRS 676
D G+NA +S L +F + G + + + V D G+PPRS
Sbjct: 594 GDSGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRS 653
Query: 677 ATATVSLFVMDENDNAPTVTLPK 699
ATAT+ L ++D + P + LP+
Sbjct: 654 ATATLHLLLVD-GFSQPYLPLPE 675
Score = 213 bits (541), Expect = 1e-54
Identities = 182/620 (29%), Positives = 278/620 (44%), Gaps = 75/620 (12%)
Query: 270 LAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLH----- 324
++EN+A GT RA D D G+NG Y T S ++ + G +++
Sbjct: 142 ISENTAEGTAFRLERAQDPDGGLNGIQNY-----TISPNSFFHINISGGDEGMIYPELVL 196
Query: 325 --RIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSI-----EIRKIGRIP 377
+DREE +L T+ A D G P ++ +TV + + D NDN P E + P
Sbjct: 197 DKALDREEQGELSLTLTALDGGSPSRSGTSTVRIVVLDVNDNAPQFAQALYETQAPENSP 256
Query: 378 LKDGVANV-AEDVLVDTPI-ALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNK 435
+ + V AEDV D+ + A V S D EN T FQ+ P S
Sbjct: 257 IGFLIVKVWAEDV--DSGVNAEVSYSFFDASENIRTT--------FQINPFSG------- 299
Query: 436 KKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPP-----MFGQ 490
+ FL LDYE + + I A+D G LS+ ++V+V DTNDNPP F
Sbjct: 300 -EIFLREL--LDYELVNSYKINIQAMDGGG--LSARCRVLVEVLDTNDNPPELIVSSFSN 354
Query: 491 SVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNT-V 549
SV E N P +A D DSG+N ++ + ++ + ++ IL+
Sbjct: 355 SVAE------NSPETPLAVFKINDRDSGENGKMVCYIQENLPFLLKPSVENFYILITEGA 408
Query: 550 LDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNS 609
LDRE Y + D G P L+ + V V+D NDN P F Q +T +V+EN P
Sbjct: 409 LDREIRAEYNITITVTDLGTPRLKTEHNITVLVSDVNDNAPAFTQTSYTLFVRENNSPAL 468
Query: 610 PVGMVTVMDADKGRNAEMSLYIEENNN-------IFSIENDTGTIYSTMSFDREHQTTYT 662
+G V+ D D G NA+++ + + + SI D G +++ S D E +
Sbjct: 469 HIGSVSATDRDSGTNAQVTYSLLPPQDPHLPLASLVSINADNGHLFALRSLDYEALQAFE 528
Query: 663 FRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLPKNISYT----LLPPSSNVRTVVAT 718
FRV A D G P S A V + V+D NDN+P V P L+P ++ +V
Sbjct: 529 FRVGATDRGSPALSREALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTK 588
Query: 719 VLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSG 778
V+A D D G NA L+Y ++ LF + +G V L+++ HRLVV V D+G
Sbjct: 589 VVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDNG 648
Query: 779 QPSQSTTTLVHVFVNESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVV 838
+P +S T +H+ + + S ++PL + E + +V+ +
Sbjct: 649 EPPRSATATLHLLLVDGFSQP-----------YLPLPEAAPAQAQAEADLLTVYLVVALA 697
Query: 839 AGIMTVILIILIVVMARYCR 858
+ +L +L+ V R CR
Sbjct: 698 SVSSLFLLSVLLFVAVRLCR 717
>gi|14195616 protocadherin beta 9 precursor [Homo sapiens]
Length = 797
Score = 277 bits (708), Expect = 5e-74
Identities = 206/684 (30%), Positives = 321/684 (46%), Gaps = 59/684 (8%)
Query: 35 RYRLAEEGPADVRIGNVASDLGIVTGS----GEVTFSLESGSEYLKIDNLTGELSTSERR 90
RY + EE + N+A DLG+ G G S + +YL +D+ TG L T+E+
Sbjct: 32 RYSVTEETEKGSFVVNLAKDLGLAEGELAARGTRVVS-DDNKQYLLLDSHTGNLLTNEK- 89
Query: 91 IDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDINDNTPTFPSPVLTL 150
+DREKL + C L F++ + P Q ++ ++ V DIND++P F + L
Sbjct: 90 LDREKL-----CGPKEPCMLYFQILMDDPFQ----IYRAELRVRDINDHSPVFRHKEMVL 140
Query: 151 TVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYPGGG 210
+ EN GT + L A D D G N I+ Y + S + +G+ + YP
Sbjct: 141 KISENTAEGTAFRLERAQDPDEGHNSIQNYTI-----SSNSFFHIKISGSDEGMIYPELV 195
Query: 211 GNGASGGGSGGS-KRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQPQLIVKGVYEAD 269
+ A L A +GG + G +S + V D D Q + +YE
Sbjct: 196 LDKALDREEQEELSLTLTALDGGSPSRSG--TSTIRIVVLDVNDNAPQ---FAQALYETQ 250
Query: 270 LAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLHRIDRE 329
ENS G+ I+++ A D D GVN ++ Y F A+E + +++ SG + + +D E
Sbjct: 251 APENSPVGSLIVKVSAGDADSGVNAEVSYSFFDASEDILTTFQINPFSGEIFLRELLDYE 310
Query: 330 EVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDV 389
VN + + A D G + + TV++ + D NDN P + I L + VA + +
Sbjct: 311 LVNSYKINIQAMDGG--GLSARCTVLIKVLDSNDNPPELIISS-----LSNSVAENSPGI 363
Query: 390 LVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYE 449
+ +A+ ++ DRD GENG C V ++PF LKP+ D Y L T LD E
Sbjct: 364 V----LAVFKIKDRDSGENGKTICYVQDNLPFFLKPSVD-------NFYILMTEGALDRE 412
Query: 450 ATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVAT 509
+ E+N+ I D G+P L + +S+ ++V D NDN P F Q+ ++ ENN P + +
Sbjct: 413 SKAEYNITITVTDLGTPRLKTEHSITLQVSDVNDNAPAFTQTSYTLFVRENNSPALHIGS 472
Query: 510 VLATDADSGKNAEIAYSL------DSSVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVN 563
V ATD DSG NA++ YSL + + +I+ D+G + LD E ++F+V
Sbjct: 473 VSATDRDSGTNAQVTYSLLPPQDPHLPLASLVSINADNGHLFALRSLDYEALQAFDFRVG 532
Query: 564 AKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDV------FTFYVKENLQPNSPVGMVTVM 617
A D+G P L V V V D NDN P + + T V +P V V +
Sbjct: 533 ASDRGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAV 592
Query: 618 DADKGRNAEMS--LYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPR 675
D D G+NA +S L +F + G + + + V D G+PPR
Sbjct: 593 DGDSGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPR 652
Query: 676 SATATVSLFVMDENDNAPTVTLPK 699
SATAT+ + ++D + P + LP+
Sbjct: 653 SATATLHVLLVD-GFSQPYLPLPE 675
Score = 215 bits (547), Expect = 2e-55
Identities = 179/636 (28%), Positives = 285/636 (44%), Gaps = 62/636 (9%)
Query: 245 ELQVADTPDGE---KQPQLIVKGVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFG 301
EL+V D D + ++++K ++EN+A GT RA D D G N Y
Sbjct: 120 ELRVRDINDHSPVFRHKEMVLK------ISENTAEGTAFRLERAQDPDEGHNSIQNYTIS 173
Query: 302 AATESVRRLLRLDETSGWLSVL--HRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIK 359
+ + ++ DE + ++ +DREE +L T+ A D G P ++ +T+ + +
Sbjct: 174 SNSFFHIKISGSDEGMIYPELVLDKALDREEQEELSLTLTALDGGSPSRSGTSTIRIVVL 233
Query: 360 DENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGD- 418
D NDN P E+ V + I V D D G N V+ +
Sbjct: 234 DVNDNAPQFAQALYE--------TQAPENSPVGSLIVKVSAGDADSGVNAEVSYSFFDAS 285
Query: 419 ----VPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSL 474
FQ+ P S + FL LDYE + + I A+D G LS+ ++
Sbjct: 286 EDILTTFQINPFSG--------EIFLREL--LDYELVNSYKINIQAMDGGG--LSARCTV 333
Query: 475 IVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGI 534
++KV D+NDNPP S + EN+ PG +A D DSG+N + + ++
Sbjct: 334 LIKVLDSNDNPPELIISSLSNSVAENS-PGIVLAVFKIKDRDSGENGKTICYVQDNLPFF 392
Query: 535 FAIDPDSGDILVNT-VLDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFM 593
D+ IL+ LDRE Y + D G P L+ ++ +QV+D NDN P F
Sbjct: 393 LKPSVDNFYILMTEGALDRESKAEYNITITVTDLGTPRLKTEHSITLQVSDVNDNAPAFT 452
Query: 594 QDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENNN-------IFSIENDTGT 646
Q +T +V+EN P +G V+ D D G NA+++ + + + SI D G
Sbjct: 453 QTSYTLFVRENNSPALHIGSVSATDRDSGTNAQVTYSLLPPQDPHLPLASLVSINADNGH 512
Query: 647 IYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLPKNISYT-- 704
+++ S D E + FRV A D G P S+ A V + V+D NDN+P V P
Sbjct: 513 LFALRSLDYEALQAFDFRVGASDRGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPC 572
Query: 705 --LLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSLVGKLTQ 762
L+P ++ +V V+A D D G NA L+Y ++ LF + +G V L++
Sbjct: 573 TELVPRAAEPGYLVTKVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSE 632
Query: 763 KHYGLHRLVVQVNDSGQPSQSTTTLVHVFVNESVSNATAIDSQIARSLHIPLTQDIAGDP 822
+ HRLVV V D+G+P +S T +HV + + S ++PL +
Sbjct: 633 RDAAKHRLVVLVKDNGEPPRSATATLHVLLVDGFSQP-----------YLPLPEAAPAQA 681
Query: 823 SYEISKQRLSIVIGVVAGIMTVILIILIVVMARYCR 858
++ L + + V+ + +L +L+ V R CR
Sbjct: 682 QADLLTVYLVVALASVSSLF--LLSVLLFVAVRLCR 715
Score = 197 bits (500), Expect = 7e-50
Identities = 154/541 (28%), Positives = 249/541 (46%), Gaps = 44/541 (8%)
Query: 308 RRLLRLDETSGWLSVLHRIDRE------EVNQLRFTVMARDRGQPPKTDKATVVLNIKDE 361
++ L LD +G L ++DRE E L F ++ D Q + + L ++D
Sbjct: 72 KQYLLLDSHTGNLLTNEKLDREKLCGPKEPCMLYFQILMDDPFQIYRAE-----LRVRDI 126
Query: 362 NDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPF 421
ND+ P +++ V ++E+ T L + D D+G N + T+ + F
Sbjct: 127 NDHSPVFRHKEM--------VLKISENTAEGTAFRLERAQDPDEGHNSIQNYTISSNSFF 178
Query: 422 QLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDT 481
+K + EG + L LD E E ++ + A+D GSPS S +++ + V D
Sbjct: 179 HIKISGSDEGMIYPE---LVLDKALDREEQEELSLTLTALDGGSPSRSGTSTIRIVVLDV 235
Query: 482 NDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSL---DSSVMGIFAID 538
NDN P F Q++ E PEN+ G + V A DADSG NAE++YS ++ F I+
Sbjct: 236 NDNAPQFAQALYETQAPENSPVGSLIVKVSAGDADSGVNAEVSYSFFDASEDILTTFQIN 295
Query: 539 PDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFT 598
P SG+I + +LD E + Y+ + A D G L TV+++V D NDN P+ + +
Sbjct: 296 PFSGEIFLRELLDYELVNSYKINIQAMDGG--GLSARCTVLIKVLDSNDNPPELIISSLS 353
Query: 599 FYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTM---SFDR 655
V EN P + + + D D G N + Y+++N F ++ Y M + DR
Sbjct: 354 NSVAEN-SPGIVLAVFKIKDRDSGENGKTICYVQDNLPFF-LKPSVDNFYILMTEGALDR 411
Query: 656 EHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSNVRTV 715
E + Y + D G P +++L V D NDNAP T SYTL +N +
Sbjct: 412 ESKAEYNITITVTDLGTPRLKTEHSITLQVSDVNDNAPAFT---QTSYTLFVRENNSPAL 468
Query: 716 -VATVLATDSDDGINADLNYSIVGGNP-----FKLFEIDPTSGVVSLVGKLTQKHYGLHR 769
+ +V ATD D G NA + YS++ L I+ +G + + L +
Sbjct: 469 HIGSVSATDRDSGTNAQVTYSLLPPQDPHLPLASLVSINADNGHLFALRSLDYEALQAFD 528
Query: 770 LVVQVNDSGQPSQSTTTLVHVFVNESVSNATAIDSQIARSLHIPLTQDI--AGDPSYEIS 827
V +D G P+ S+ LV V V ++ N+ + + P T+ + A +P Y ++
Sbjct: 529 FRVGASDRGSPALSSEALVRVLVLDANDNSPFVLYPLQNG-SAPCTELVPRAAEPGYLVT 587
Query: 828 K 828
K
Sbjct: 588 K 588
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.132 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 48,438,743
Number of Sequences: 37866
Number of extensions: 2515823
Number of successful extensions: 25329
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 350
Number of HSP's successfully gapped in prelim test: 226
Number of HSP's that attempted gapping in prelim test: 11014
Number of HSP's gapped (non-prelim): 4863
length of query: 1200
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1086
effective length of database: 13,930,794
effective search space: 15128842284
effective search space used: 15128842284
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.