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Search of human proteins with 143770880
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|143770880 laminin, beta 4 [Homo sapiens]
(1761 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|143770880 laminin, beta 4 [Homo sapiens] 3731 0.0
gi|167614504 laminin, beta 1 precursor [Homo sapiens] 1456 0.0
gi|119703755 laminin, beta 2 precursor [Homo sapiens] 1375 0.0
gi|62868217 laminin, beta 3 precursor [Homo sapiens] 447 e-125
gi|62868215 laminin, beta 3 precursor [Homo sapiens] 447 e-125
gi|189083719 laminin, beta 3 precursor [Homo sapiens] 447 e-125
gi|93204871 netrin 4 [Homo sapiens] 351 3e-96
gi|145309326 laminin, gamma 1 precursor [Homo sapiens] 311 3e-84
gi|38788416 laminin, alpha 1 precursor [Homo sapiens] 289 2e-77
gi|21264602 laminin alpha 5 [Homo sapiens] 285 2e-76
gi|110611156 laminin, gamma 3 precursor [Homo sapiens] 277 7e-74
gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens] 270 7e-72
gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens] 270 7e-72
gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo s... 262 2e-69
gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sa... 262 2e-69
gi|219842266 usherin isoform B [Homo sapiens] 251 3e-66
gi|219842259 usherin isoform A [Homo sapiens] 251 3e-66
gi|148613884 netrin 1 [Homo sapiens] 246 1e-64
gi|5453810 netrin 3 [Homo sapiens] 210 1e-53
gi|164414431 netrin G1 isoform 1 [Homo sapiens] 180 1e-44
gi|122937440 multiple EGF-like-domains 9 [Homo sapiens] 174 7e-43
gi|181336739 multiple EGF-like-domains 11 [Homo sapiens] 171 4e-42
gi|190014607 netrin G2 [Homo sapiens] 167 8e-41
gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens] 166 2e-40
gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens] 164 5e-40
gi|157419122 laminin, alpha 4 isoform 2 precursor [Homo sapiens] 164 5e-40
gi|122937343 platelet endothelial aggregation receptor 1 [Homo s... 164 7e-40
gi|14192943 multiple EGF-like-domains 10 [Homo sapiens] 163 1e-39
gi|24308065 netrin 5 [Homo sapiens] 163 2e-39
gi|157419140 laminin, gamma 2 isoform b precursor [Homo sapiens] 158 5e-38
>gi|143770880 laminin, beta 4 [Homo sapiens]
Length = 1761
Score = 3731 bits (9675), Expect = 0.0
Identities = 1761/1761 (100%), Positives = 1761/1761 (100%)
Query: 1 MQFQLTLFLHLGWLSYSKAQDDCNRGACHPTTGDLLVGRNTQLMASSTCGLSRAQKYCIL 60
MQFQLTLFLHLGWLSYSKAQDDCNRGACHPTTGDLLVGRNTQLMASSTCGLSRAQKYCIL
Sbjct: 1 MQFQLTLFLHLGWLSYSKAQDDCNRGACHPTTGDLLVGRNTQLMASSTCGLSRAQKYCIL 60
Query: 61 SYLEGEQKCFICDSRFPYDPYDQPNSHTIENVIVSFEPDREKKWWQSENGLDHVSIRLDL 120
SYLEGEQKCFICDSRFPYDPYDQPNSHTIENVIVSFEPDREKKWWQSENGLDHVSIRLDL
Sbjct: 61 SYLEGEQKCFICDSRFPYDPYDQPNSHTIENVIVSFEPDREKKWWQSENGLDHVSIRLDL 120
Query: 121 EALFRFSHLILTFKTFRPAAMLVERSTDYGHNWKVFKYFAKDCATSFPNITSGQAQGVGD 180
EALFRFSHLILTFKTFRPAAMLVERSTDYGHNWKVFKYFAKDCATSFPNITSGQAQGVGD
Sbjct: 121 EALFRFSHLILTFKTFRPAAMLVERSTDYGHNWKVFKYFAKDCATSFPNITSGQAQGVGD 180
Query: 181 IVCDSKYSDIEPSTGGEVVLKVLDPSFEIENPYSPYIQDLVTLTNLRINFTKLHTLGDAL 240
IVCDSKYSDIEPSTGGEVVLKVLDPSFEIENPYSPYIQDLVTLTNLRINFTKLHTLGDAL
Sbjct: 181 IVCDSKYSDIEPSTGGEVVLKVLDPSFEIENPYSPYIQDLVTLTNLRINFTKLHTLGDAL 240
Query: 241 LGRRQNDSLDKYYYALYEMIVRGSCFCNGHASECRPMQKMRGDVFSPPGMVHGQCVCQHN 300
LGRRQNDSLDKYYYALYEMIVRGSCFCNGHASECRPMQKMRGDVFSPPGMVHGQCVCQHN
Sbjct: 241 LGRRQNDSLDKYYYALYEMIVRGSCFCNGHASECRPMQKMRGDVFSPPGMVHGQCVCQHN 300
Query: 301 TDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCE 360
TDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCE
Sbjct: 301 TDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCE 360
Query: 361 DCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSHSDPALGSVA 420
DCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSHSDPALGSVA
Sbjct: 361 DCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSHSDPALGSVA 420
Query: 421 GQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSY 480
GQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSY
Sbjct: 421 GQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSY 480
Query: 481 VTGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPA 540
VTGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPA
Sbjct: 481 VTGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPA 540
Query: 541 PGYFFAPLNFYLYEAEEATTLQGLAPLGSETFGQSPAVHVVLGEPVPGNPVTWTGPGFAR 600
PGYFFAPLNFYLYEAEEATTLQGLAPLGSETFGQSPAVHVVLGEPVPGNPVTWTGPGFAR
Sbjct: 541 PGYFFAPLNFYLYEAEEATTLQGLAPLGSETFGQSPAVHVVLGEPVPGNPVTWTGPGFAR 600
Query: 601 VLPGAGLRFAVNNIPFPVDFTIAIHYETQSAADWTVQIVVNPPGGSEHCIPKTLQSKPQS 660
VLPGAGLRFAVNNIPFPVDFTIAIHYETQSAADWTVQIVVNPPGGSEHCIPKTLQSKPQS
Sbjct: 601 VLPGAGLRFAVNNIPFPVDFTIAIHYETQSAADWTVQIVVNPPGGSEHCIPKTLQSKPQS 660
Query: 661 FALPAATRIMLLPTPICLEPDVQYSIDVYFSQPLQGESHAHSHVLVDSLGLIPQINSLEN 720
FALPAATRIMLLPTPICLEPDVQYSIDVYFSQPLQGESHAHSHVLVDSLGLIPQINSLEN
Sbjct: 661 FALPAATRIMLLPTPICLEPDVQYSIDVYFSQPLQGESHAHSHVLVDSLGLIPQINSLEN 720
Query: 721 FCSKQDLDEYQLHNCVEIASAMGPQVLPGACERLIISMSAKLHDGAVACKCHPQGSVGSS 780
FCSKQDLDEYQLHNCVEIASAMGPQVLPGACERLIISMSAKLHDGAVACKCHPQGSVGSS
Sbjct: 721 FCSKQDLDEYQLHNCVEIASAMGPQVLPGACERLIISMSAKLHDGAVACKCHPQGSVGSS 780
Query: 781 CSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHGCHPCHCHPQGSKDTVCDQVTGQCPCHG 840
CSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHGCHPCHCHPQGSKDTVCDQVTGQCPCHG
Sbjct: 781 CSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHGCHPCHCHPQGSKDTVCDQVTGQCPCHG 840
Query: 841 EVSGRRCDRCLAGYFGFPSCHPCPCNRFAELCDPETGSCFNCGGFTTGRNCERCIDGYYG 900
EVSGRRCDRCLAGYFGFPSCHPCPCNRFAELCDPETGSCFNCGGFTTGRNCERCIDGYYG
Sbjct: 841 EVSGRRCDRCLAGYFGFPSCHPCPCNRFAELCDPETGSCFNCGGFTTGRNCERCIDGYYG 900
Query: 901 NPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNP 960
NPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNP
Sbjct: 901 NPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNP 960
Query: 961 RISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQLCKPGHYGSALNQTCR 1020
RISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQLCKPGHYGSALNQTCR
Sbjct: 961 RISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQLCKPGHYGSALNQTCR 1020
Query: 1021 RCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCADGYWNLVPGRGCQSC 1080
RCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCADGYWNLVPGRGCQSC
Sbjct: 1021 RCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCADGYWNLVPGRGCQSC 1080
Query: 1081 DCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSECQENYYGDPPGRCIPCDCNRAGTQKPIC 1140
DCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSECQENYYGDPPGRCIPCDCNRAGTQKPIC
Sbjct: 1081 DCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSECQENYYGDPPGRCIPCDCNRAGTQKPIC 1140
Query: 1141 DPDTGMCRCREGVSGQRCDRCARGHSQEFPTCLQCHLCFDQWDHTISSLSKAVQGLMRLA 1200
DPDTGMCRCREGVSGQRCDRCARGHSQEFPTCLQCHLCFDQWDHTISSLSKAVQGLMRLA
Sbjct: 1141 DPDTGMCRCREGVSGQRCDRCARGHSQEFPTCLQCHLCFDQWDHTISSLSKAVQGLMRLA 1200
Query: 1201 ANMEDKRETLPVCEADFKDLRGNVSEIERILKHPVFPSGKFLKVKDYHDSVRRQIMQLNE 1260
ANMEDKRETLPVCEADFKDLRGNVSEIERILKHPVFPSGKFLKVKDYHDSVRRQIMQLNE
Sbjct: 1201 ANMEDKRETLPVCEADFKDLRGNVSEIERILKHPVFPSGKFLKVKDYHDSVRRQIMQLNE 1260
Query: 1261 QLKAVYEFQDLKDTIERAKNEADLLLEDLQEEIDLQSSVLNASIADSSENIKKYYHISSS 1320
QLKAVYEFQDLKDTIERAKNEADLLLEDLQEEIDLQSSVLNASIADSSENIKKYYHISSS
Sbjct: 1261 QLKAVYEFQDLKDTIERAKNEADLLLEDLQEEIDLQSSVLNASIADSSENIKKYYHISSS 1320
Query: 1321 AEKKINETSSTINTSANTRNDLLTILDTLTSKGNLSLERLKQIKIPDIQILNEKVCGDPG 1380
AEKKINETSSTINTSANTRNDLLTILDTLTSKGNLSLERLKQIKIPDIQILNEKVCGDPG
Sbjct: 1321 AEKKINETSSTINTSANTRNDLLTILDTLTSKGNLSLERLKQIKIPDIQILNEKVCGDPG 1380
Query: 1381 NVPCVPLPCGGALCTGRKGHRKCRGPGCHGSLTLSTNALQKAQEAKSIIRNLDKQVRGLK 1440
NVPCVPLPCGGALCTGRKGHRKCRGPGCHGSLTLSTNALQKAQEAKSIIRNLDKQVRGLK
Sbjct: 1381 NVPCVPLPCGGALCTGRKGHRKCRGPGCHGSLTLSTNALQKAQEAKSIIRNLDKQVRGLK 1440
Query: 1441 NQIESISEQAEVSKNNALQLREKLGNIRNQSDSEEENINLFIKKVKNFLLEENVPPEDIE 1500
NQIESISEQAEVSKNNALQLREKLGNIRNQSDSEEENINLFIKKVKNFLLEENVPPEDIE
Sbjct: 1441 NQIESISEQAEVSKNNALQLREKLGNIRNQSDSEEENINLFIKKVKNFLLEENVPPEDIE 1500
Query: 1501 KVANGVLDIHLPIPSQNLTDELVKIQKHMQLCEDYRTDENRLNEEADGAQKLLVKAKAAE 1560
KVANGVLDIHLPIPSQNLTDELVKIQKHMQLCEDYRTDENRLNEEADGAQKLLVKAKAAE
Sbjct: 1501 KVANGVLDIHLPIPSQNLTDELVKIQKHMQLCEDYRTDENRLNEEADGAQKLLVKAKAAE 1560
Query: 1561 KAANILLNLDKTLNQLQQAQITQGRANSTITQLTANITKIKKNVLQAENQTREMKSELEL 1620
KAANILLNLDKTLNQLQQAQITQGRANSTITQLTANITKIKKNVLQAENQTREMKSELEL
Sbjct: 1561 KAANILLNLDKTLNQLQQAQITQGRANSTITQLTANITKIKKNVLQAENQTREMKSELEL 1620
Query: 1621 AKQRSGLEDGLSLLQTKLQRHQDHAVNAKVQAESAQHQAGSLEKEFVELKKQYAILQRKT 1680
AKQRSGLEDGLSLLQTKLQRHQDHAVNAKVQAESAQHQAGSLEKEFVELKKQYAILQRKT
Sbjct: 1621 AKQRSGLEDGLSLLQTKLQRHQDHAVNAKVQAESAQHQAGSLEKEFVELKKQYAILQRKT 1680
Query: 1681 STTGLTKETLGKVKQLKDAAEKLAGDTEAKIRRITDLERKIQDLNLSRQAKADQLRILED 1740
STTGLTKETLGKVKQLKDAAEKLAGDTEAKIRRITDLERKIQDLNLSRQAKADQLRILED
Sbjct: 1681 STTGLTKETLGKVKQLKDAAEKLAGDTEAKIRRITDLERKIQDLNLSRQAKADQLRILED 1740
Query: 1741 QVVAIKNEIVEQEKKYARCYS 1761
QVVAIKNEIVEQEKKYARCYS
Sbjct: 1741 QVVAIKNEIVEQEKKYARCYS 1761
>gi|167614504 laminin, beta 1 precursor [Homo sapiens]
Length = 1786
Score = 1456 bits (3769), Expect = 0.0
Identities = 733/1785 (41%), Positives = 1037/1785 (58%), Gaps = 77/1785 (4%)
Query: 23 CNRGACHPTTGDLLVGRNTQLMASSTCGLSRAQKYCILSYLEGEQKCFICDSRFPYDPYD 82
C G+C+P TGDLL+GR +L +STCGL + + YCI+S+L+ ++KCFIC+S+ PY
Sbjct: 30 CAEGSCYPATGDLLIGRAQKLSVTSTCGLHKPEPYCIVSHLQEDKKCFICNSQDPYHETL 89
Query: 83 QPNSHTIENVIVSFEPDREKKWWQSENGLDHVSIRLDLEALFRFSHLILTFKTFRPAAML 142
P+SH IENV+ +F P+R K WWQSENG+++V+I+LDLEA F F+HLI+TFKTFRPAAML
Sbjct: 90 NPDSHLIENVVTTFAPNRLKIWWQSENGVENVTIQLDLEAEFHFTHLIMTFKTFRPAAML 149
Query: 143 VERSTDYGHNWKVFKYFAKDCATSFPNITSGQAQGVGDIVCDSKYSDIEPSTGGEVVLKV 202
+ERS+D+G W V++YFA DC SFP I++G + V DI+CDS+YSDIEPST GEV+ +
Sbjct: 150 IERSSDFGKTWGVYRYFAYDCEASFPGISTGPMKKVDDIICDSRYSDIEPSTEGEVIFRA 209
Query: 203 LDPSFEIENPYSPYIQDLVTLTNLRINFTKLHTLGDALLGRRQNDSLDKYYYALYEMIVR 262
LDP+F+IE+PYSP IQ+L+ +TNLRI F KLHTLGD LL R + +KYYYA+Y+M+VR
Sbjct: 210 LDPAFKIEDPYSPRIQNLLKITNLRIKFVKLHTLGDNLLDSRM-EIREKYYYAVYDMVVR 268
Query: 263 GSCFCNGHASECRPMQKMRGDVFSPPGMVHGQCVCQHNTDGPNCERCKDFFQDAPWRPAA 322
G+CFC GHASEC P+ +V GMVHG C+C+HNT G NCE C DF+ D PWRPA
Sbjct: 269 GNCFCYGHASECAPVDGFNEEV---EGMVHGHCMCRHNTKGLNCELCMDFYHDLPWRPAE 325
Query: 323 DLQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDP 382
NAC+ C+CN HS CHFDM YLA+G +SGGVC+DCQHNT G++C++C+P +Y+ P
Sbjct: 326 GRNSNACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHP 385
Query: 383 LKTISDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHY 442
+ I DP C C CDP G+ + GIC S++D + G +AGQC CK NVEG CD CK Y
Sbjct: 386 ERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFY 445
Query: 443 GLSATDPLGCQPCDCNPLGSLP-FLTCDVDTGQCLCLSYVTGAHCEECTVGYWGLGNHLH 501
LS+ DP GC+ C CNPLG++P CD +TG C C VTG HC++C +WGL N L
Sbjct: 446 DLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDLD 505
Query: 502 GCSPCDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPAPGYFFAPLNFYLYEAEEATTL 561
GC PCDCD+GGA +N C ++GQC CRPH+ GR C+E PGY+FA L+ YLYEAEEA
Sbjct: 506 GCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEPGYYFATLDHYLYEAEEANL- 564
Query: 562 QGLAPLGSETFGQSPAVHVVLGEPVPGNPVTWTGPGFARVLPGAGLRFAVNNIPFPVDFT 621
P V +V + + +WTG GF RV GA L F ++NIP+ +++
Sbjct: 565 -------------GPGVSIVERQYIQDRIPSWTGAGFVRVPEGAYLEFFIDNIPYSMEYD 611
Query: 622 IAIHYETQSAADWTVQIV-VNPPG---GSEHCIPKTLQSKPQSFALPAATRIMLLPTPIC 677
I I YE Q W ++ V PG S C Q +L +R ++LP P+C
Sbjct: 612 ILIRYEPQLPDHWEKAVITVQRPGRIPTSSRCGNTIPDDDNQVVSLSPGSRYVVLPRPVC 671
Query: 678 LEPDVQYSIDVYFSQPLQGESHAHS-HVLVDSLGLIPQINSLENF---------CSKQDL 727
E Y++ + Q +S S + L+DSL L+P SL+ F +
Sbjct: 672 FEKGTNYTVRLELPQYTSSDSDVESPYTLIDSLVLMPYCKSLDIFTVGGSGDGVVTNSAW 731
Query: 728 DEYQLHNCVEIASAMGPQVLPGACERLIISMSAKLHDGAVACKCHPQGSVGSSCSRLGGQ 787
+ +Q + C+E + ++ + C +I S+SA LH +AC+C PQGS+ S C GGQ
Sbjct: 732 ETFQRYRCLENSRSVVKTPMTDVCRNIIFSISALLHQTGLACECDPQGSLSSVCDPNGGQ 791
Query: 788 CQCKPLVVGRCCDRCSTGSYDLGHHGCHPCHCHPQGSKDTVCDQVTGQCPCHGEVSGRRC 847
CQC+P VVGR C+RC+ G++ G GC PC CH QGS + C+ VTGQC C V R+C
Sbjct: 792 CQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQC 851
Query: 848 DRCLAGYFGFPSCHPCPCNRFAELCDPETGSCFNCGGFTTGRNCERCIDGYYGNP--SSG 905
DRCL G++GFPSC PC CN A+ CDP TG C NC +T G NCERC+ GYYG+P SG
Sbjct: 852 DRCLPGHWGFPSCQPCQCNGHADDCDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSG 911
Query: 906 QPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGA 965
CRPC CPD P S + FA SCYQ+ + + C C GY G++C +C++G++GNP G
Sbjct: 912 DHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGG 971
Query: 966 PCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQLCKPGHYGSALNQTCRRCSCH 1025
CQPC C+NNID TDPE+C + TG CL+CL++T+G +CQ C+ G+YG AL Q CR+C C+
Sbjct: 972 SCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFGYYGDALQQDCRKCVCN 1031
Query: 1026 ASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCADGYWNLVPGRGCQSCDCDPR 1085
G C G C CD TG C CLPNV G CDRCA W L G GC C+C+
Sbjct: 1032 YLGTVQEHC--NGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQLASGTGCDPCNCNAA 1089
Query: 1086 TSQSSHCDQLTGQCPCKLGYGGKRCSECQENYYGDPPGRCIPCDCNRAGTQKPICDPDTG 1145
S C++ TGQC C G+GG+ CSECQE ++GDP C CDC+ G + P CD TG
Sbjct: 1090 HSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVECRACDCDPRGIETPQCDQSTG 1149
Query: 1146 MCRCREGVSGQRCDRCARGHSQEFPTCLQCHLCFDQWDHTISSLSKAVQGLMRLAANMED 1205
C C EGV G RCD+C RG+S FP C CH CF WD I+ L+ + A ++
Sbjct: 1150 QCVCVEGVEGPRCDKCTRGYSGVFPDCTPCHQCFALWDVIIAELTNRTHRFLEKAKALKI 1209
Query: 1206 KRETLPVCEADFKDLRGNVSEIERILKHPVFPSGKFLK------------VKDYHDSVRR 1253
P E + VSEI+ IL P+ + LK +KD + + +
Sbjct: 1210 SGVIGPYRET-VDSVERKVSEIKDILAQS--PAAEPLKNIGNLFEEAEKLIKDVTEMMAQ 1266
Query: 1254 QIMQLNEQLKAVYEFQDLKDTIERAKNEADLLLEDLQEEIDLQSSVLNASIADSSENIKK 1313
++L++ D+++ D +++L E+++ + N+ I + ++I K
Sbjct: 1267 VEVKLSDTTSQSNSTAKELDSLQTEAESLDNTVKELAEQLEF---IKNSDIRGALDSITK 1323
Query: 1314 YYHISSSAEKKIN----ETSSTINTSANTRNDLLTIL--------DTLTSKGNLSLERLK 1361
Y+ +S AE+++N E +ST+ SA R+ + ++ + + L E
Sbjct: 1324 YFQMSLEAEERVNASTTEPNSTVEQSALMRDRVEDVMMERESQFKEKQEEQARLLDELAG 1383
Query: 1362 QIKIPDIQILNEKVCGDPGNVPCVPLPCGGALCTGRKGHRKCRGPGCHGSLTLSTNALQK 1421
+++ D+ E CG P C CGG C +G RKC GPGC G +T++ NA QK
Sbjct: 1384 KLQSLDLSAAAEMTCGTPPGASCSETECGGPNCRTDEGERKCGGPGCGGLVTVAHNAWQK 1443
Query: 1422 AQEAKSIIRNLDKQVRGLKNQIESISEQAEVSKNNALQLREKLGNIRNQSDSEEENINLF 1481
A + + + +V L + +A+ +K +A + K + + D E +
Sbjct: 1444 AMDLDQDVLSALAEVEQLSKMVSEAKLRADEAKQSAEDILLKTNATKEKMDKSNEELRNL 1503
Query: 1482 IKKVKNFLLEENVPPEDIEKVANGVLDIHLPIPSQNLTDELVKIQKHMQLCEDYRTDENR 1541
IK+++NFL +++ + IE VAN VL + +P Q L + I++ ++
Sbjct: 1504 IKQIRNFLTQDSADLDSIEAVANEVLKMEMPSTPQQLQNLTEDIRERVESLSQVEVILQH 1563
Query: 1542 LNEEADGAQKLLVKAKAAEKAA-NILLNLDKTLNQLQQAQITQGRANSTITQLTANITKI 1600
+ A+ LL +AK A K+A ++ + D L++A+ Q A I Q +I
Sbjct: 1564 SAADIARAEMLLEEAKRASKSATDVKVTADMVKEALEEAEKAQVAAEKAIKQADEDIQGT 1623
Query: 1601 KKNVLQAENQTREMKSELELAKQR-SGLEDGLSLLQTKLQRHQDHAVNAK----VQAESA 1655
+ + E++T + L A QR S LE + L+ K ++ A + +SA
Sbjct: 1624 QNLLTSIESETAASEETLFNASQRISELERNVEELKRKAAQNSGEAEYIEKVVYTVKQSA 1683
Query: 1656 QHQAGSLEKEFVE-LKKQYAILQRKTSTTGLTKETLGKVKQLKDAAEKLAGDTEAKIRRI 1714
+ +L+ E E KK ++ +KT + + K + L++ A+ L +K++ +
Sbjct: 1684 EDVKKTLDGELDEKYKKVENLIAKKTEESA---DARRKAEMLQNEAKTLLAQANSKLQLL 1740
Query: 1715 TDLERKIQDLNLSRQAKADQLRILEDQVVAIKNEIVEQEKKYARC 1759
DLERK +D + KA +L LE +V ++ +I ++ Y+ C
Sbjct: 1741 KDLERKYEDNQRYLEDKAQELARLEGEVRSLLKDISQKVAVYSTC 1785
>gi|119703755 laminin, beta 2 precursor [Homo sapiens]
Length = 1798
Score = 1375 bits (3560), Expect = 0.0
Identities = 718/1817 (39%), Positives = 1035/1817 (56%), Gaps = 91/1817 (5%)
Query: 1 MQFQLTLFLHLGWLSYSKAQ------DDCNRGACHPTTGDLLVGRNTQLMASSTCGLSRA 54
+ ++L L L L L+ + AQ C+RG+C+P TGDLLVGR +L ASSTCGL+
Sbjct: 14 LPWELRLGLLLSVLAATLAQAPAPDVPGCSRGSCYPATGDLLVGRADRLTASSTCGLNGP 73
Query: 55 QKYCILSYLEGEQKCFICDSRFPYDPYDQPNSHTIENVIVSFEPDREKKWWQSENGLDHV 114
Q YCI+S+L+ E+KCF+CDSR P+ D P+SH I+NV+ SF P R WWQSENG+ V
Sbjct: 74 QPYCIVSHLQDEKKCFLCDSRRPFSARDNPHSHRIQNVVTSFAPQRRAAWWQSENGIPAV 133
Query: 115 SIRLDLEALFRFSHLILTFKTFRPAAMLVERSTDYGHNWKVFKYFAKDCATSFPNITSGQ 174
+I+LDLEA F F+HLI+TFKTFRPAAMLVERS D+G W V++YF+ DC FP +
Sbjct: 134 TIQLDLEAEFHFTHLIMTFKTFRPAAMLVERSADFGRTWHVYRYFSYDCGADFPGVPLAP 193
Query: 175 AQGVGDIVCDSKYSDIEPSTGGEVVLKVLDPSFEIENPYSPYIQDLVTLTNLRINFTKLH 234
+ D+VC+S+YS+IEPST GEV+ +VLDP+ I +PYS IQ+L+ +TNLR+N T+LH
Sbjct: 194 PRHWDDVVCESRYSEIEPSTEGEVIYRVLDPAIPIPDPYSSRIQNLLKITNLRVNLTRLH 253
Query: 235 TLGDALLGRRQNDSLDKYYYALYEMIVRGSCFCNGHASECRPMQKMRGDVFSPPGMVHGQ 294
TLGD LL R+ + +KYYYALYE++VRG+CFC GHASEC P G GMVHG
Sbjct: 254 TLGDNLLDPRR-EIREKYYYALYELVVRGNCFCYGHASECAPAP---GAPAHAEGMVHGA 309
Query: 295 CVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASGGL 354
C+C+HNT G NCE+C+DF++D PWRPA D +ACR C C+ H+ CHFDM YLASG +
Sbjct: 310 CICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLASGNV 369
Query: 355 SGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSHSDP 414
SGGVC+ CQHNT G+HC+ CRP FYRDP K + DP C C+CDP G+ GG C SH DP
Sbjct: 370 SGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDP 429
Query: 415 ALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLT-CDVDTG 473
ALG V+GQC CKE+V G +C QC+ +GLS +D LGC+ C CN G++P T CD ++G
Sbjct: 430 ALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSG 489
Query: 474 QCLCLSYVTGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYSNVCSPKNGQCECRPHVTG 533
C C VTG C+ C G+WGL + L GC PCDCD+GGA C GQC CR H+ G
Sbjct: 490 SCYCKRLVTGRGCDRCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVG 549
Query: 534 RSCSEPAPGYFFAPLNFYLYEAEEATTLQGLAPLGSETFGQSPAVHVVLGEPVPGNPVTW 593
R C + PGYF L+ ++EAE +T GQ + VV PG +W
Sbjct: 550 RRCEQVQPGYFRPFLDHLIWEAE-------------DTRGQ--VLDVVERLVTPGETPSW 594
Query: 594 TGPGFARVLPGAGLRFAVNNIPFPVDFTIAIHYETQSAADWT-VQIVVNPPGG------S 646
TG GF R+ G L F V ++P +D+ + + E Q W ++++V PG
Sbjct: 595 TGSGFVRLQEGQTLEFLVASVPKAMDYDLLLRLEPQVPEQWAELELIVQRPGPVPAHSLC 654
Query: 647 EHCIPKTLQSKPQSFALPAATRIMLLPTPICLEPDVQYSID---VYFSQPLQGES-HAHS 702
H +PK + Q P A R ++ P P+CLEP + Y + V Q E+ ++
Sbjct: 655 GHLVPK--DDRIQGTLQPHA-RYLIFPNPVCLEPGISYKLHLKLVRTGGSAQPETPYSGP 711
Query: 703 HVLVDSLGLIPQINSLENFCS--------KQDLDEYQLHNCVEIASAMGPQVLPGACERL 754
+L+DSL L+P++ LE F + + YQ H + S P AC L
Sbjct: 712 GLLIDSLVLLPRVLVLEMFSGGDAAALERQATFERYQCHEEGLVPSKTSPS---EACAPL 768
Query: 755 IISMSAKLHDGAVACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHGC 814
+IS+S +++GA+ C+C+PQGS+ S C+ GGQC CKP VVGR CD C+ G Y G GC
Sbjct: 769 LISLSTLIYNGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTGC 828
Query: 815 HPCHCHPQGSKDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFPSCHPCPCNRFAELCDP 874
C C +G+ ++C++ +GQC C G RCDRC G +GFPSC PC CN A+ C+
Sbjct: 829 QACQCSHEGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFPSCRPCVCNGHADECNT 888
Query: 875 ETGSCFNCGGFTTGRNCERCIDGYYGNP--SSGQPCRPCLCPDDPSSNQYFAHSCYQNLW 932
TG+C C T G +CERCI G++G+P G CRPC CP+ P S ++FA SC+Q+ +
Sbjct: 889 HTGACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEY 948
Query: 933 SSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECL 992
S ++C+C GYTG +C C+ G +G+P G CQ C C+ NID DP++C TG+CL
Sbjct: 949 SQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCL 1008
Query: 993 RCLHNTQGANCQLCKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPC 1052
RCLH+T+G +C CKPG +G A Q+C RC+C+ G +P +C P C CDP +G CPC
Sbjct: 1009 RCLHHTEGPHCAHCKPGFHGQAARQSCHRCTCNLLGTNPQQC-PSPDQCHCDPSSGQCPC 1067
Query: 1053 LPNVTGLACDRCADGYWNLVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSE 1112
LPNV G +CDRCA +WNL G GCQ C C P ++ C++ TGQC C+ G+GG+ CSE
Sbjct: 1068 LPNVQGPSCDRCAPNFWNLTSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSE 1127
Query: 1113 CQENYYGDPPGRCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDRCARGHSQEFPTC 1172
CQE ++GDP +C CDC+ G P C TG C CR GVSG RCD+CARG S FP C
Sbjct: 1128 CQELHWGDPGLQCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARGFSGIFPAC 1187
Query: 1173 LQCHLCFDQWDHTISSLSKAVQGLMRLAANMEDKRETLPVCEADFKDLRGNVSEIERILK 1232
CH CF WD + L+ Q L + A ++ + L E+ F ++ + ++ I+
Sbjct: 1188 HPCHACFGDWDRVVQDLAARTQRLEQRAQELQ-QTGVLGAFESSFWHMQEKLGIVQGIVG 1246
Query: 1233 HPVFPSGKFLKVKDYHDSVRRQIMQLNEQLKAV-YEFQDLKDT----------IERAKNE 1281
+ ++ + + +RR+I + E L + + D++D +ER +
Sbjct: 1247 ARNTSAASTAQLVEATEELRREIGEATEHLTQLEADLTDVQDENFNANHALSGLERDRLA 1306
Query: 1282 ADLLLEDLQEEIDLQSSVLNASIADSSENIKKYYHISSSAEKKINETS----STINTSAN 1337
+L L L + +DL + +++ + ++I+ + S+ AE++ N ++ S ++ SA+
Sbjct: 1307 LNLTLRQLDQHLDL---LKHSNFLGAYDSIRHAHSQSAEAERRANTSALAVPSPVSNSAS 1363
Query: 1338 TRNDLLTILDT----LTSKGNLSLERLKQIKIP----DIQILNEKVCGDPGNVPCVPLPC 1389
R+ ++D SK + L ++ + +NE VCG PG+ PC PC
Sbjct: 1364 ARHRTEALMDAQKEDFNSKHMANQRALGKLSAHTHTLSLTDINELVCGAPGDAPCATSPC 1423
Query: 1390 GGALCTGRKGHRKCRGPGCHGSLTLSTNALQKAQEAKSIIRNLDKQVRGLKNQIESISEQ 1449
GGA C G +C G C+G+ + AL +A+ ++ ++ + + +++ Q
Sbjct: 1424 GGAGCRDEDGQPRCGGLSCNGAAATADLALGRARHTQAELQRALAEGGSILSRVAETRRQ 1483
Query: 1450 AEVSKNNALQLREKLGNIRNQSDSEEENINLFIKKVKNFLLEENVPPEDIEKVANGVLDI 1509
A ++ A +K R Q + + + I+ VK+FL +E P+ IE VA VL++
Sbjct: 1484 ASEAQQRAQAALDKANASRGQVEQANQELQELIQSVKDFLNQEGADPDSIEMVATRVLEL 1543
Query: 1510 HLPIPSQNLTDELVKIQKHMQLCEDYRTDENRLNEEADGAQKLLVKAKAAEKAANILLNL 1569
+P ++ + I + ++ D R + A++LL A+ A A
Sbjct: 1544 SIPASAEQIQHLAGAIAERVRSLADVDAILARTVGDVRRAEQLLQDARRARSWAEDEKQK 1603
Query: 1570 DKTLN-QLQQAQITQGRANSTITQLTANITKIKKNVLQAENQTREMKSELELAKQRSGLE 1628
+T+ L++AQ QG A I A+ ++ + Q + + + L A +R+
Sbjct: 1604 AETVQAALEEAQRAQGIAQGAIRGAVADTRDTEQTLYQVQERMAGAERALSSAGERARQL 1663
Query: 1629 DG-LSLLQTKLQRHQDHAVNAKVQAESAQHQAGSLEKEF-VELKKQY----AILQRKTST 1682
D L L+ K + A A+ A SAQ +A E+ L QY A+ +RK
Sbjct: 1664 DALLEALKLKRAGNSLAASTAEETAGSAQGRAQEAEQLLRGPLGDQYQTVKALAERKAQG 1723
Query: 1683 TGLTKETLGKVKQLKDAAEKLAGDTEAKIRRITDLERKIQDLNLSRQAKADQLRILEDQV 1742
+ + +QL+D A L + K++R+ +LE ++ + ++KA QL LE ++
Sbjct: 1724 VLAAQ---ARAEQLRDEARDLLQAAQDKLQRLQELEGTYEENERALESKAAQLDGLEARM 1780
Query: 1743 VAIKNEIVEQEKKYARC 1759
++ I Q + Y C
Sbjct: 1781 RSVLQAINLQVQIYNTC 1797
>gi|62868217 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 447 bits (1150), Expect = e-125
Identities = 225/523 (43%), Positives = 306/523 (58%), Gaps = 25/523 (4%)
Query: 19 AQDDCNRGACHPTTGDLLVGRNTQLMASSTCGLSRAQKYCILSYLEGEQKCFICDSRFPY 78
AQ C+RGAC+P GDLLVGR L ASSTCGL++ + YC Y E + KC CDSR P+
Sbjct: 17 AQQACSRGACYPPVGDLLVGRTRFLRASSTCGLTKPETYCT-QYGEWQMKCCKCDSRQPH 75
Query: 79 DPYDQPNSHTIENVIVSFEPDREKKWWQSENGLDHVSIRLDLEALFRFSHLILTFKTFRP 138
+ Y SH +ENV S P R WWQS+N ++ VS++LDL+ F+ +++ F+ P
Sbjct: 76 NYY----SHRVENVASSSGPMR---WWQSQNDVNPVSLQLDLDRRFQLQEVMMEFQGPMP 128
Query: 139 AAMLVERSTDYGHNWKVFKYFAKDCATSFPNITSGQAQGVGDIVCDSKYSDIEPS-TGGE 197
A ML+ERS+D+G W+V++Y A DC ++FP + G+ Q D+ C S GG+
Sbjct: 129 AGMLIERSSDFGKTWRVYQYLAADCTSTFPRVRQGRPQSWQDVRCQSLPQRPNARLNGGK 188
Query: 198 VVLKVLDPSFEIENPYSPYIQDLVTLTNLRINFTKLHTLGDALLGRRQNDSLDKYYYALY 257
V L ++D I S IQ++ +TNLR+NFT+L + ++ YYA+
Sbjct: 189 VQLNLMDLVSGIPATQSQKIQEVGEITNLRVNFTRLAPVP------QRGYHPPSAYYAVS 242
Query: 258 EMIVRGSCFCNGHASECRPMQKMRGDVFSPPGMVHGQCVCQHNTDGPNCERCKDFFQDAP 317
++ ++GSCFC+GHA C P S VH CVCQHNT GPNCERC F+ + P
Sbjct: 243 QLRLQGSCFCHGHADRCAPKPGASAGP-STAVQVHDVCVCQHNTAGPNCERCAPFYNNRP 301
Query: 318 WRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPL 377
WRPA + C+ C CN HS CHFD + AS G GGVC++C+ +TEG++C+RC+
Sbjct: 302 WRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLH 361
Query: 378 FYRDPLKTISDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQC 437
++R+ S CI CECDPDG + G C DP V GQC+CKE+V+G +CD C
Sbjct: 362 YFRNRRPGASIQETCISCECDPDGAVPGAPC----DP----VTGQCVCKEHVQGERCDLC 413
Query: 438 KPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGLG 497
KP GL+ +P GC CDCN LGS + CD ++G+CLCL V G C++C +W L
Sbjct: 414 KPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLA 473
Query: 498 NHLHGCSPCDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPA 540
+ GC PC CD + S C+ GQC CR G CS A
Sbjct: 474 SG-QGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAA 515
Score = 357 bits (917), Expect = 4e-98
Identities = 248/939 (26%), Positives = 426/939 (45%), Gaps = 59/939 (6%)
Query: 863 CPCNRFAELCDPETGSCFN------------CGGFTTGRNCERCIDGYYGN----PSSGQ 906
C C+ A+ C P+ G+ C T G NCERC +Y N P+ GQ
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAP-FYNNRPWRPAEGQ 308
Query: 907 P---CRPCLCPDDPSSNQYFAHSCYQNLWSSDVIC-NCLQGYTGTQCGECSTGFYGNPRI 962
C+ C C + + + + +C NC G C C ++ N R
Sbjct: 309 DAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRP 368
Query: 963 SGAPCQPC-ACNNNIDVTDPES-CSRVTGECLRCLHNTQGANCQLCKPGHYGS--ALNQT 1018
+ + C +C + D P + C VTG+C+ C + QG C LCKPG G A Q
Sbjct: 369 GASIQETCISCECDPDGAVPGAPCDPVTGQCV-CKEHVQGERCDLCKPGFTGLTYANPQG 427
Query: 1019 CRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCADGYWNLVPGRGCQ 1078
C RC C+ G S + P CD +G C CLPNV G CD+CA +W L G+GC+
Sbjct: 428 CHRCDCNILG-SRRDMP-------CDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCE 479
Query: 1079 SCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCS-----ECQENYYGDPPGRCIPCDCNRA 1133
C CDP S S C+Q TGQCPC+ G+GG CS +C + YGD C CDC+
Sbjct: 480 PCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFR 539
Query: 1134 GTQKPICDPDTGMCRCREGVSGQRCDRCARGHSQEFPTCLQCHLCFDQWDHTISSLSKAV 1193
GT+ P CD +G C CR G++G RCD+C RG+ +P C+ CH CF +D + +
Sbjct: 540 GTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVACHPCFQTYDADLREQALRF 599
Query: 1194 QGLMRLAAN------MEDKRETLPVCEADFKDLRGNVSEIERILKHPVFPSGKFLKVKDY 1247
L A+ +ED+ + +A + + +I +L P + +V
Sbjct: 600 GRLRNATASLWSGPGLEDRGLASRILDA-----KSKIEQIRAVLSSPAVTEQEVAQVASA 654
Query: 1248 HDSVRRQIMQLNEQLKAVYEFQDLKDTIERAKNEADLLLEDLQEEIDLQSSVLNASIADS 1307
S+RR + L L E L +E + LL Q + + + +A + +
Sbjct: 655 ILSLRRTLQGLQLDLPLEEETLSLPRDLESLDRSFNGLLTMYQRKREQFEKISSADPSGA 714
Query: 1308 SENIKKYYHISSSAEKKINETSSTINTSANTRNDLLTILDTL-----TSKGNLSLERLKQ 1362
+ Y S+ A ++++++S ++ ++R + ++ T L RL+
Sbjct: 715 FRMLSTAYEQSAQAAQQVSDSSRLLDQLRDSRREAERLVRQAGGGGGTGSPKLVALRLEM 774
Query: 1363 IKIPDIQILNEKVCGDPGNVPCVPLPCGGALCTGRKGHRKCRGPGCHGSLTLSTNALQKA 1422
+PD+ K+CG+ + C P+ C G LC G G C G L + A A
Sbjct: 775 SSLPDLTPTFNKLCGNSRQMACTPISCPGELCPQDNG--TACGSRCRGVLPRAGGAFLMA 832
Query: 1423 QEAKSIIRNLDKQVRGLKNQIESISEQAEVSKNNALQLREKLGNIRNQSDSEEENINLFI 1482
+ +R + Q++ + I + E A +++A +L ++ R+Q + + L I
Sbjct: 833 GQVAEQLRGFNAQLQRTRQMIRAAEESASQIQSSAQRLETQVSASRSQMEEDVRRTRLLI 892
Query: 1483 KKVKNFLLEENVPPEDIEKVANGVLDIHLPIPSQNLTDELVKIQKHMQLCEDYRTDENRL 1542
++V++FL + + I++V+ VL + LP S + ++ +IQ + ++
Sbjct: 893 QQVRDFLTDPDTDAATIQEVSEAVLALWLPTDSATVLQKMNEIQAIAARLPNVDLVLSQT 952
Query: 1543 NEEADGAQKLLVKAKAAEKAANILL-NLDKTLNQLQQAQITQGRANSTITQLTANITKIK 1601
++ A++L +A+ A A+ + ++ + L+Q + A T+ + ++ I+
Sbjct: 953 KQDIARARRLQAEAEEARSRAHAVEGQVEDVVGNLRQGTVALQEAQDTMQGTSRSLRLIQ 1012
Query: 1602 KNVLQAENQTREM-KSELELAKQRSGLEDGLSLLQTKLQRHQDHAVNAKVQAESAQHQAG 1660
V + + R K + KQ + L+ + ++ AV A+ AE A QA
Sbjct: 1013 DRVAEVQQVLRPAEKLVTSMTKQLGDFWTRMEELRHQARQQGAEAVQAQQLAEGASEQAL 1072
Query: 1661 SLEKEFVELKKQYAILQRKTSTTGLTKETLGKVKQLKDAAEKLAGDTEAKIRRITDLERK 1720
S ++ F +K++YA L+ + + + E +++ +K AE+L G+T + R+ D+E +
Sbjct: 1073 SAQEGFERIKQKYAELKDRLGQSSMLGEQGARIQSVKTEAEELFGETMEMMDRMKDMELE 1132
Query: 1721 IQDLNLSRQAKADQLRILEDQVVAIKNEIVEQEKKYARC 1759
+ + + ++ L LE +V I++ I + YA C
Sbjct: 1133 LLRGSQAIMLRSADLTGLEKRVEQIRDHINGRVLYYATC 1171
Score = 114 bits (285), Expect = 8e-25
Identities = 81/267 (30%), Positives = 106/267 (39%), Gaps = 47/267 (17%)
Query: 771 CHPQGSV-GSSCSRLGGQCQ-CKPLVVGRCCDRCSTGSYDLGHHG------CHPCHCHPQ 822
CH +V +S GG C C+ G+ C+RC + G C C C P
Sbjct: 325 CHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPD 384
Query: 823 GS-KDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGF-----PSCHPCPCN----RFAELC 872
G+ CD VTGQC C V G RCD C G+ G CH C CN R C
Sbjct: 385 GAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPC 444
Query: 873 DPETGSCFNCGGFTTGRNCERCIDGYYGNPSSGQPCRPCLCPD----DPSSNQYFAHSCY 928
D E+G C C G C++C Y+ +SGQ C PC C P NQ+
Sbjct: 445 DEESGRCL-CLPNVVGPKCDQCAP-YHWKLASGQGCEPCACDPHNSLSPQCNQFTGQ--- 499
Query: 929 QNLWSSDVICNCLQGYTGTQCG-----ECSTGFYGNPRISGAPCQPCACNNNIDVTDPES 983
C C +G+ G C +C YG+ C+ C C + T+
Sbjct: 500 ---------CPCREGFGGLMCSAAAIRQCPDRTYGD---VATGCRACDC--DFRGTEGPG 545
Query: 984 CSRVTGECLRCLHNTQGANCQLCKPGH 1010
C + +G CL C G C C+ G+
Sbjct: 546 CDKASGRCL-CRPGLTGPRCDQCQRGY 571
Score = 113 bits (282), Expect = 2e-24
Identities = 73/236 (30%), Positives = 107/236 (45%), Gaps = 26/236 (11%)
Query: 760 AKLHDGAVACKCHPQGSV-GSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGH---HGCH 815
A + + ++C+C P G+V G+ C + GQC CK V G CD C G L + GCH
Sbjct: 370 ASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCH 429
Query: 816 PCHCHPQGS-KDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFPS---CHPCPC---NRF 868
C C+ GS +D CD+ +G+C C V G +CD+C ++ S C PC C N
Sbjct: 430 RCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSL 489
Query: 869 AELCDPETGSCFNCGGF----TTGRNCERCIDGYYGNPSSGQPCRPCLCPDDPSSNQYFA 924
+ C+ TG C GF + +C D YG+ ++G CR C C F
Sbjct: 490 SPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATG--CRACDCD--------FR 539
Query: 925 HSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTD 980
+ + C C G TG +C +C G+ + A C PC + D+ +
Sbjct: 540 GTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVA-CHPCFQTYDADLRE 594
Score = 40.0 bits (92), Expect = 0.020
Identities = 26/91 (28%), Positives = 31/91 (34%), Gaps = 27/91 (29%)
Query: 475 CLCLSYVTGAHCEECTVGY----W--GLGNHLHGCSPCDCD---------------IGGA 513
C+C G +CE C Y W G H C CDC+ GA
Sbjct: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGA 338
Query: 514 YSNVCSPKNGQCECRPHVTGRSCSEPAPGYF 544
Y VC CR H G++C YF
Sbjct: 339 YGGVCD------NCRDHTEGKNCERCQLHYF 363
>gi|62868215 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 447 bits (1150), Expect = e-125
Identities = 225/523 (43%), Positives = 306/523 (58%), Gaps = 25/523 (4%)
Query: 19 AQDDCNRGACHPTTGDLLVGRNTQLMASSTCGLSRAQKYCILSYLEGEQKCFICDSRFPY 78
AQ C+RGAC+P GDLLVGR L ASSTCGL++ + YC Y E + KC CDSR P+
Sbjct: 17 AQQACSRGACYPPVGDLLVGRTRFLRASSTCGLTKPETYCT-QYGEWQMKCCKCDSRQPH 75
Query: 79 DPYDQPNSHTIENVIVSFEPDREKKWWQSENGLDHVSIRLDLEALFRFSHLILTFKTFRP 138
+ Y SH +ENV S P R WWQS+N ++ VS++LDL+ F+ +++ F+ P
Sbjct: 76 NYY----SHRVENVASSSGPMR---WWQSQNDVNPVSLQLDLDRRFQLQEVMMEFQGPMP 128
Query: 139 AAMLVERSTDYGHNWKVFKYFAKDCATSFPNITSGQAQGVGDIVCDSKYSDIEPS-TGGE 197
A ML+ERS+D+G W+V++Y A DC ++FP + G+ Q D+ C S GG+
Sbjct: 129 AGMLIERSSDFGKTWRVYQYLAADCTSTFPRVRQGRPQSWQDVRCQSLPQRPNARLNGGK 188
Query: 198 VVLKVLDPSFEIENPYSPYIQDLVTLTNLRINFTKLHTLGDALLGRRQNDSLDKYYYALY 257
V L ++D I S IQ++ +TNLR+NFT+L + ++ YYA+
Sbjct: 189 VQLNLMDLVSGIPATQSQKIQEVGEITNLRVNFTRLAPVP------QRGYHPPSAYYAVS 242
Query: 258 EMIVRGSCFCNGHASECRPMQKMRGDVFSPPGMVHGQCVCQHNTDGPNCERCKDFFQDAP 317
++ ++GSCFC+GHA C P S VH CVCQHNT GPNCERC F+ + P
Sbjct: 243 QLRLQGSCFCHGHADRCAPKPGASAGP-STAVQVHDVCVCQHNTAGPNCERCAPFYNNRP 301
Query: 318 WRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPL 377
WRPA + C+ C CN HS CHFD + AS G GGVC++C+ +TEG++C+RC+
Sbjct: 302 WRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLH 361
Query: 378 FYRDPLKTISDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQC 437
++R+ S CI CECDPDG + G C DP V GQC+CKE+V+G +CD C
Sbjct: 362 YFRNRRPGASIQETCISCECDPDGAVPGAPC----DP----VTGQCVCKEHVQGERCDLC 413
Query: 438 KPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGLG 497
KP GL+ +P GC CDCN LGS + CD ++G+CLCL V G C++C +W L
Sbjct: 414 KPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLA 473
Query: 498 NHLHGCSPCDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPA 540
+ GC PC CD + S C+ GQC CR G CS A
Sbjct: 474 SG-QGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAA 515
Score = 357 bits (917), Expect = 4e-98
Identities = 248/939 (26%), Positives = 426/939 (45%), Gaps = 59/939 (6%)
Query: 863 CPCNRFAELCDPETGSCFN------------CGGFTTGRNCERCIDGYYGN----PSSGQ 906
C C+ A+ C P+ G+ C T G NCERC +Y N P+ GQ
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAP-FYNNRPWRPAEGQ 308
Query: 907 P---CRPCLCPDDPSSNQYFAHSCYQNLWSSDVIC-NCLQGYTGTQCGECSTGFYGNPRI 962
C+ C C + + + + +C NC G C C ++ N R
Sbjct: 309 DAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRP 368
Query: 963 SGAPCQPC-ACNNNIDVTDPES-CSRVTGECLRCLHNTQGANCQLCKPGHYGS--ALNQT 1018
+ + C +C + D P + C VTG+C+ C + QG C LCKPG G A Q
Sbjct: 369 GASIQETCISCECDPDGAVPGAPCDPVTGQCV-CKEHVQGERCDLCKPGFTGLTYANPQG 427
Query: 1019 CRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCADGYWNLVPGRGCQ 1078
C RC C+ G S + P CD +G C CLPNV G CD+CA +W L G+GC+
Sbjct: 428 CHRCDCNILG-SRRDMP-------CDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCE 479
Query: 1079 SCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCS-----ECQENYYGDPPGRCIPCDCNRA 1133
C CDP S S C+Q TGQCPC+ G+GG CS +C + YGD C CDC+
Sbjct: 480 PCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFR 539
Query: 1134 GTQKPICDPDTGMCRCREGVSGQRCDRCARGHSQEFPTCLQCHLCFDQWDHTISSLSKAV 1193
GT+ P CD +G C CR G++G RCD+C RG+ +P C+ CH CF +D + +
Sbjct: 540 GTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVACHPCFQTYDADLREQALRF 599
Query: 1194 QGLMRLAAN------MEDKRETLPVCEADFKDLRGNVSEIERILKHPVFPSGKFLKVKDY 1247
L A+ +ED+ + +A + + +I +L P + +V
Sbjct: 600 GRLRNATASLWSGPGLEDRGLASRILDA-----KSKIEQIRAVLSSPAVTEQEVAQVASA 654
Query: 1248 HDSVRRQIMQLNEQLKAVYEFQDLKDTIERAKNEADLLLEDLQEEIDLQSSVLNASIADS 1307
S+RR + L L E L +E + LL Q + + + +A + +
Sbjct: 655 ILSLRRTLQGLQLDLPLEEETLSLPRDLESLDRSFNGLLTMYQRKREQFEKISSADPSGA 714
Query: 1308 SENIKKYYHISSSAEKKINETSSTINTSANTRNDLLTILDTL-----TSKGNLSLERLKQ 1362
+ Y S+ A ++++++S ++ ++R + ++ T L RL+
Sbjct: 715 FRMLSTAYEQSAQAAQQVSDSSRLLDQLRDSRREAERLVRQAGGGGGTGSPKLVALRLEM 774
Query: 1363 IKIPDIQILNEKVCGDPGNVPCVPLPCGGALCTGRKGHRKCRGPGCHGSLTLSTNALQKA 1422
+PD+ K+CG+ + C P+ C G LC G G C G L + A A
Sbjct: 775 SSLPDLTPTFNKLCGNSRQMACTPISCPGELCPQDNG--TACGSRCRGVLPRAGGAFLMA 832
Query: 1423 QEAKSIIRNLDKQVRGLKNQIESISEQAEVSKNNALQLREKLGNIRNQSDSEEENINLFI 1482
+ +R + Q++ + I + E A +++A +L ++ R+Q + + L I
Sbjct: 833 GQVAEQLRGFNAQLQRTRQMIRAAEESASQIQSSAQRLETQVSASRSQMEEDVRRTRLLI 892
Query: 1483 KKVKNFLLEENVPPEDIEKVANGVLDIHLPIPSQNLTDELVKIQKHMQLCEDYRTDENRL 1542
++V++FL + + I++V+ VL + LP S + ++ +IQ + ++
Sbjct: 893 QQVRDFLTDPDTDAATIQEVSEAVLALWLPTDSATVLQKMNEIQAIAARLPNVDLVLSQT 952
Query: 1543 NEEADGAQKLLVKAKAAEKAANILL-NLDKTLNQLQQAQITQGRANSTITQLTANITKIK 1601
++ A++L +A+ A A+ + ++ + L+Q + A T+ + ++ I+
Sbjct: 953 KQDIARARRLQAEAEEARSRAHAVEGQVEDVVGNLRQGTVALQEAQDTMQGTSRSLRLIQ 1012
Query: 1602 KNVLQAENQTREM-KSELELAKQRSGLEDGLSLLQTKLQRHQDHAVNAKVQAESAQHQAG 1660
V + + R K + KQ + L+ + ++ AV A+ AE A QA
Sbjct: 1013 DRVAEVQQVLRPAEKLVTSMTKQLGDFWTRMEELRHQARQQGAEAVQAQQLAEGASEQAL 1072
Query: 1661 SLEKEFVELKKQYAILQRKTSTTGLTKETLGKVKQLKDAAEKLAGDTEAKIRRITDLERK 1720
S ++ F +K++YA L+ + + + E +++ +K AE+L G+T + R+ D+E +
Sbjct: 1073 SAQEGFERIKQKYAELKDRLGQSSMLGEQGARIQSVKTEAEELFGETMEMMDRMKDMELE 1132
Query: 1721 IQDLNLSRQAKADQLRILEDQVVAIKNEIVEQEKKYARC 1759
+ + + ++ L LE +V I++ I + YA C
Sbjct: 1133 LLRGSQAIMLRSADLTGLEKRVEQIRDHINGRVLYYATC 1171
Score = 114 bits (285), Expect = 8e-25
Identities = 81/267 (30%), Positives = 106/267 (39%), Gaps = 47/267 (17%)
Query: 771 CHPQGSV-GSSCSRLGGQCQ-CKPLVVGRCCDRCSTGSYDLGHHG------CHPCHCHPQ 822
CH +V +S GG C C+ G+ C+RC + G C C C P
Sbjct: 325 CHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPD 384
Query: 823 GS-KDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGF-----PSCHPCPCN----RFAELC 872
G+ CD VTGQC C V G RCD C G+ G CH C CN R C
Sbjct: 385 GAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPC 444
Query: 873 DPETGSCFNCGGFTTGRNCERCIDGYYGNPSSGQPCRPCLCPD----DPSSNQYFAHSCY 928
D E+G C C G C++C Y+ +SGQ C PC C P NQ+
Sbjct: 445 DEESGRCL-CLPNVVGPKCDQCAP-YHWKLASGQGCEPCACDPHNSLSPQCNQFTGQ--- 499
Query: 929 QNLWSSDVICNCLQGYTGTQCG-----ECSTGFYGNPRISGAPCQPCACNNNIDVTDPES 983
C C +G+ G C +C YG+ C+ C C + T+
Sbjct: 500 ---------CPCREGFGGLMCSAAAIRQCPDRTYGD---VATGCRACDC--DFRGTEGPG 545
Query: 984 CSRVTGECLRCLHNTQGANCQLCKPGH 1010
C + +G CL C G C C+ G+
Sbjct: 546 CDKASGRCL-CRPGLTGPRCDQCQRGY 571
Score = 113 bits (282), Expect = 2e-24
Identities = 73/236 (30%), Positives = 107/236 (45%), Gaps = 26/236 (11%)
Query: 760 AKLHDGAVACKCHPQGSV-GSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGH---HGCH 815
A + + ++C+C P G+V G+ C + GQC CK V G CD C G L + GCH
Sbjct: 370 ASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCH 429
Query: 816 PCHCHPQGS-KDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFPS---CHPCPC---NRF 868
C C+ GS +D CD+ +G+C C V G +CD+C ++ S C PC C N
Sbjct: 430 RCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSL 489
Query: 869 AELCDPETGSCFNCGGF----TTGRNCERCIDGYYGNPSSGQPCRPCLCPDDPSSNQYFA 924
+ C+ TG C GF + +C D YG+ ++G CR C C F
Sbjct: 490 SPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATG--CRACDCD--------FR 539
Query: 925 HSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTD 980
+ + C C G TG +C +C G+ + A C PC + D+ +
Sbjct: 540 GTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVA-CHPCFQTYDADLRE 594
Score = 40.0 bits (92), Expect = 0.020
Identities = 26/91 (28%), Positives = 31/91 (34%), Gaps = 27/91 (29%)
Query: 475 CLCLSYVTGAHCEECTVGY----W--GLGNHLHGCSPCDCD---------------IGGA 513
C+C G +CE C Y W G H C CDC+ GA
Sbjct: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGA 338
Query: 514 YSNVCSPKNGQCECRPHVTGRSCSEPAPGYF 544
Y VC CR H G++C YF
Sbjct: 339 YGGVCD------NCRDHTEGKNCERCQLHYF 363
>gi|189083719 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 447 bits (1150), Expect = e-125
Identities = 225/523 (43%), Positives = 306/523 (58%), Gaps = 25/523 (4%)
Query: 19 AQDDCNRGACHPTTGDLLVGRNTQLMASSTCGLSRAQKYCILSYLEGEQKCFICDSRFPY 78
AQ C+RGAC+P GDLLVGR L ASSTCGL++ + YC Y E + KC CDSR P+
Sbjct: 17 AQQACSRGACYPPVGDLLVGRTRFLRASSTCGLTKPETYCT-QYGEWQMKCCKCDSRQPH 75
Query: 79 DPYDQPNSHTIENVIVSFEPDREKKWWQSENGLDHVSIRLDLEALFRFSHLILTFKTFRP 138
+ Y SH +ENV S P R WWQS+N ++ VS++LDL+ F+ +++ F+ P
Sbjct: 76 NYY----SHRVENVASSSGPMR---WWQSQNDVNPVSLQLDLDRRFQLQEVMMEFQGPMP 128
Query: 139 AAMLVERSTDYGHNWKVFKYFAKDCATSFPNITSGQAQGVGDIVCDSKYSDIEPS-TGGE 197
A ML+ERS+D+G W+V++Y A DC ++FP + G+ Q D+ C S GG+
Sbjct: 129 AGMLIERSSDFGKTWRVYQYLAADCTSTFPRVRQGRPQSWQDVRCQSLPQRPNARLNGGK 188
Query: 198 VVLKVLDPSFEIENPYSPYIQDLVTLTNLRINFTKLHTLGDALLGRRQNDSLDKYYYALY 257
V L ++D I S IQ++ +TNLR+NFT+L + ++ YYA+
Sbjct: 189 VQLNLMDLVSGIPATQSQKIQEVGEITNLRVNFTRLAPVP------QRGYHPPSAYYAVS 242
Query: 258 EMIVRGSCFCNGHASECRPMQKMRGDVFSPPGMVHGQCVCQHNTDGPNCERCKDFFQDAP 317
++ ++GSCFC+GHA C P S VH CVCQHNT GPNCERC F+ + P
Sbjct: 243 QLRLQGSCFCHGHADRCAPKPGASAGP-STAVQVHDVCVCQHNTAGPNCERCAPFYNNRP 301
Query: 318 WRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPL 377
WRPA + C+ C CN HS CHFD + AS G GGVC++C+ +TEG++C+RC+
Sbjct: 302 WRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLH 361
Query: 378 FYRDPLKTISDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQC 437
++R+ S CI CECDPDG + G C DP V GQC+CKE+V+G +CD C
Sbjct: 362 YFRNRRPGASIQETCISCECDPDGAVPGAPC----DP----VTGQCVCKEHVQGERCDLC 413
Query: 438 KPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGLG 497
KP GL+ +P GC CDCN LGS + CD ++G+CLCL V G C++C +W L
Sbjct: 414 KPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLA 473
Query: 498 NHLHGCSPCDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPA 540
+ GC PC CD + S C+ GQC CR G CS A
Sbjct: 474 SG-QGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAA 515
Score = 357 bits (917), Expect = 4e-98
Identities = 248/939 (26%), Positives = 426/939 (45%), Gaps = 59/939 (6%)
Query: 863 CPCNRFAELCDPETGSCFN------------CGGFTTGRNCERCIDGYYGN----PSSGQ 906
C C+ A+ C P+ G+ C T G NCERC +Y N P+ GQ
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAP-FYNNRPWRPAEGQ 308
Query: 907 P---CRPCLCPDDPSSNQYFAHSCYQNLWSSDVIC-NCLQGYTGTQCGECSTGFYGNPRI 962
C+ C C + + + + +C NC G C C ++ N R
Sbjct: 309 DAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRP 368
Query: 963 SGAPCQPC-ACNNNIDVTDPES-CSRVTGECLRCLHNTQGANCQLCKPGHYGS--ALNQT 1018
+ + C +C + D P + C VTG+C+ C + QG C LCKPG G A Q
Sbjct: 369 GASIQETCISCECDPDGAVPGAPCDPVTGQCV-CKEHVQGERCDLCKPGFTGLTYANPQG 427
Query: 1019 CRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCADGYWNLVPGRGCQ 1078
C RC C+ G S + P CD +G C CLPNV G CD+CA +W L G+GC+
Sbjct: 428 CHRCDCNILG-SRRDMP-------CDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCE 479
Query: 1079 SCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCS-----ECQENYYGDPPGRCIPCDCNRA 1133
C CDP S S C+Q TGQCPC+ G+GG CS +C + YGD C CDC+
Sbjct: 480 PCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFR 539
Query: 1134 GTQKPICDPDTGMCRCREGVSGQRCDRCARGHSQEFPTCLQCHLCFDQWDHTISSLSKAV 1193
GT+ P CD +G C CR G++G RCD+C RG+ +P C+ CH CF +D + +
Sbjct: 540 GTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVACHPCFQTYDADLREQALRF 599
Query: 1194 QGLMRLAAN------MEDKRETLPVCEADFKDLRGNVSEIERILKHPVFPSGKFLKVKDY 1247
L A+ +ED+ + +A + + +I +L P + +V
Sbjct: 600 GRLRNATASLWSGPGLEDRGLASRILDA-----KSKIEQIRAVLSSPAVTEQEVAQVASA 654
Query: 1248 HDSVRRQIMQLNEQLKAVYEFQDLKDTIERAKNEADLLLEDLQEEIDLQSSVLNASIADS 1307
S+RR + L L E L +E + LL Q + + + +A + +
Sbjct: 655 ILSLRRTLQGLQLDLPLEEETLSLPRDLESLDRSFNGLLTMYQRKREQFEKISSADPSGA 714
Query: 1308 SENIKKYYHISSSAEKKINETSSTINTSANTRNDLLTILDTL-----TSKGNLSLERLKQ 1362
+ Y S+ A ++++++S ++ ++R + ++ T L RL+
Sbjct: 715 FRMLSTAYEQSAQAAQQVSDSSRLLDQLRDSRREAERLVRQAGGGGGTGSPKLVALRLEM 774
Query: 1363 IKIPDIQILNEKVCGDPGNVPCVPLPCGGALCTGRKGHRKCRGPGCHGSLTLSTNALQKA 1422
+PD+ K+CG+ + C P+ C G LC G G C G L + A A
Sbjct: 775 SSLPDLTPTFNKLCGNSRQMACTPISCPGELCPQDNG--TACGSRCRGVLPRAGGAFLMA 832
Query: 1423 QEAKSIIRNLDKQVRGLKNQIESISEQAEVSKNNALQLREKLGNIRNQSDSEEENINLFI 1482
+ +R + Q++ + I + E A +++A +L ++ R+Q + + L I
Sbjct: 833 GQVAEQLRGFNAQLQRTRQMIRAAEESASQIQSSAQRLETQVSASRSQMEEDVRRTRLLI 892
Query: 1483 KKVKNFLLEENVPPEDIEKVANGVLDIHLPIPSQNLTDELVKIQKHMQLCEDYRTDENRL 1542
++V++FL + + I++V+ VL + LP S + ++ +IQ + ++
Sbjct: 893 QQVRDFLTDPDTDAATIQEVSEAVLALWLPTDSATVLQKMNEIQAIAARLPNVDLVLSQT 952
Query: 1543 NEEADGAQKLLVKAKAAEKAANILL-NLDKTLNQLQQAQITQGRANSTITQLTANITKIK 1601
++ A++L +A+ A A+ + ++ + L+Q + A T+ + ++ I+
Sbjct: 953 KQDIARARRLQAEAEEARSRAHAVEGQVEDVVGNLRQGTVALQEAQDTMQGTSRSLRLIQ 1012
Query: 1602 KNVLQAENQTREM-KSELELAKQRSGLEDGLSLLQTKLQRHQDHAVNAKVQAESAQHQAG 1660
V + + R K + KQ + L+ + ++ AV A+ AE A QA
Sbjct: 1013 DRVAEVQQVLRPAEKLVTSMTKQLGDFWTRMEELRHQARQQGAEAVQAQQLAEGASEQAL 1072
Query: 1661 SLEKEFVELKKQYAILQRKTSTTGLTKETLGKVKQLKDAAEKLAGDTEAKIRRITDLERK 1720
S ++ F +K++YA L+ + + + E +++ +K AE+L G+T + R+ D+E +
Sbjct: 1073 SAQEGFERIKQKYAELKDRLGQSSMLGEQGARIQSVKTEAEELFGETMEMMDRMKDMELE 1132
Query: 1721 IQDLNLSRQAKADQLRILEDQVVAIKNEIVEQEKKYARC 1759
+ + + ++ L LE +V I++ I + YA C
Sbjct: 1133 LLRGSQAIMLRSADLTGLEKRVEQIRDHINGRVLYYATC 1171
Score = 114 bits (285), Expect = 8e-25
Identities = 81/267 (30%), Positives = 106/267 (39%), Gaps = 47/267 (17%)
Query: 771 CHPQGSV-GSSCSRLGGQCQ-CKPLVVGRCCDRCSTGSYDLGHHG------CHPCHCHPQ 822
CH +V +S GG C C+ G+ C+RC + G C C C P
Sbjct: 325 CHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPD 384
Query: 823 GS-KDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGF-----PSCHPCPCN----RFAELC 872
G+ CD VTGQC C V G RCD C G+ G CH C CN R C
Sbjct: 385 GAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPC 444
Query: 873 DPETGSCFNCGGFTTGRNCERCIDGYYGNPSSGQPCRPCLCPD----DPSSNQYFAHSCY 928
D E+G C C G C++C Y+ +SGQ C PC C P NQ+
Sbjct: 445 DEESGRCL-CLPNVVGPKCDQCAP-YHWKLASGQGCEPCACDPHNSLSPQCNQFTGQ--- 499
Query: 929 QNLWSSDVICNCLQGYTGTQCG-----ECSTGFYGNPRISGAPCQPCACNNNIDVTDPES 983
C C +G+ G C +C YG+ C+ C C + T+
Sbjct: 500 ---------CPCREGFGGLMCSAAAIRQCPDRTYGD---VATGCRACDC--DFRGTEGPG 545
Query: 984 CSRVTGECLRCLHNTQGANCQLCKPGH 1010
C + +G CL C G C C+ G+
Sbjct: 546 CDKASGRCL-CRPGLTGPRCDQCQRGY 571
Score = 113 bits (282), Expect = 2e-24
Identities = 73/236 (30%), Positives = 107/236 (45%), Gaps = 26/236 (11%)
Query: 760 AKLHDGAVACKCHPQGSV-GSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGH---HGCH 815
A + + ++C+C P G+V G+ C + GQC CK V G CD C G L + GCH
Sbjct: 370 ASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCH 429
Query: 816 PCHCHPQGS-KDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFPS---CHPCPC---NRF 868
C C+ GS +D CD+ +G+C C V G +CD+C ++ S C PC C N
Sbjct: 430 RCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSL 489
Query: 869 AELCDPETGSCFNCGGF----TTGRNCERCIDGYYGNPSSGQPCRPCLCPDDPSSNQYFA 924
+ C+ TG C GF + +C D YG+ ++G CR C C F
Sbjct: 490 SPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATG--CRACDCD--------FR 539
Query: 925 HSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTD 980
+ + C C G TG +C +C G+ + A C PC + D+ +
Sbjct: 540 GTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVA-CHPCFQTYDADLRE 594
Score = 40.0 bits (92), Expect = 0.020
Identities = 26/91 (28%), Positives = 31/91 (34%), Gaps = 27/91 (29%)
Query: 475 CLCLSYVTGAHCEECTVGY----W--GLGNHLHGCSPCDCD---------------IGGA 513
C+C G +CE C Y W G H C CDC+ GA
Sbjct: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGA 338
Query: 514 YSNVCSPKNGQCECRPHVTGRSCSEPAPGYF 544
Y VC CR H G++C YF
Sbjct: 339 YGGVCD------NCRDHTEGKNCERCQLHYF 363
>gi|93204871 netrin 4 [Homo sapiens]
Length = 628
Score = 351 bits (901), Expect = 3e-96
Identities = 189/465 (40%), Positives = 265/465 (56%), Gaps = 49/465 (10%)
Query: 27 ACHPTTGDLLVGRNTQLMASSTCGLSRAQKYCILSYLEG----EQKCFICDSRFPYDPYD 82
AC+P G+L +GR +L A +TCG + + YC S + KC C++ +P+ +
Sbjct: 33 ACNPRMGNLALGR--KLWADTTCGQNATELYCFYSENTDLTCRQPKCDKCNAAYPHLAH- 89
Query: 83 QPNSHTIENVIVSFEPDREKKWWQSENGLDHVSIRLDLEALFRFSHLILTFKTFRPAAML 142
+ + + + WWQS + I+LDLEA F F+HLI+ FK+ RPAAM+
Sbjct: 90 ------LPSAMADSSFRFPRTWWQSAEDVHREKIQLDLEAEFYFTHLIVMFKSPRPAAMV 143
Query: 143 VERSTDYGHNWKVFKYFAKDCATSFPNITSGQAQGVGDIVCDSKYSDIEPSTGGEVVLKV 202
++RS D+G WK +KYFA +C+ +F +G +C SKYS P TGGEV+ K
Sbjct: 144 LDRSQDFGKTWKPYKYFATNCSATFGLEDDVVKKGA---ICTSKYSSPFPCTGGEVIFKA 200
Query: 203 LDPSFEIENPYSPYIQDLVTLTNLRINFTKLHTLGDALLGRRQNDSLDK----YYYALYE 258
L P ++ ENPYS +Q+ + +TNLR+ K + ++ND ++ +YA+Y+
Sbjct: 201 LSPPYDTENPYSAKVQEQLKITNLRVQLLKRQSCPC-----QRNDLNEEPQHFTHYAIYD 255
Query: 259 MIVRGSCFCNGHASECRPMQKMRGDVFSPPG---MVHGQCVCQHNTDGPNCERCKDFFQD 315
IV+GSCFCNGHA +C P+ R PG MVHG+C+C+HNT G +C+ C + D
Sbjct: 256 FIVKGSCFCNGHADQCIPVHGFRP--VKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYND 313
Query: 316 APWRPAADLQD---NACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCD 372
PW AAD + N CR+C CN H+ CHFD+ + ASG SGGVC+DCQHNTEGQ+C
Sbjct: 314 RPWE-AADGKTGAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQ 372
Query: 373 RCRPLFYRDPLKTISDPYACIPCECDPDGT-ISGGICVSHSDPALGSVAGQCLCKENVEG 431
RC+P FYRD + S P AC PC C P G+ + V+ DP+ G C CK V G
Sbjct: 373 RCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPS----NGDCPCKPGVAG 428
Query: 432 AKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCL 476
+CD+C ++G GC+PCDC GS CD TG C+
Sbjct: 429 RRCDRCMVGYWGFG---DYGCRPCDC--AGS-----CDPITGDCI 463
Score = 119 bits (298), Expect = 3e-26
Identities = 75/227 (33%), Positives = 95/227 (41%), Gaps = 57/227 (25%)
Query: 331 SCSCNSHSSRC----HFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTI 386
SC CN H+ +C F + + G C C+HNT G HC C PL+ P +
Sbjct: 261 SCFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCM-CKHNTAGSHCQHCAPLYNDRPWEAA 319
Query: 387 SD----PYACIPCEC--------------DPDGTISGGICVSHSDPALGSVAGQCLCKEN 428
P C C+C + G SGG+C C+ N
Sbjct: 320 DGKTGAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDD--------------CQHN 365
Query: 429 VEGAKCDQCKPNHYG-----LSATDPLGCQPCDCNPLGS--LPFLT---CDVDTGQCLCL 478
EG C +CKP Y SA D C+PC C+P+GS LP + CD G C C
Sbjct: 366 TEGQYCQRCKPGFYRDLRRPFSAPD--ACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCK 423
Query: 479 SYVTGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYSNVCSPKNGQC 525
V G C+ C VGYWG G+ +GC PCDC + C P G C
Sbjct: 424 PGVAGRRCDRCMVGYWGFGD--YGCRPCDC------AGSCDPITGDC 462
Score = 95.1 bits (235), Expect = 5e-19
Identities = 67/214 (31%), Positives = 87/214 (40%), Gaps = 49/214 (22%)
Query: 970 CACNNNID----------VTDPESCSRVTGECLRCLHNTQGANCQLCKPGH----YGSAL 1015
C CN + D V P + V G+C+ C HNT G++CQ C P + + +A
Sbjct: 262 CFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCM-CKHNTAGSHCQHCAPLYNDRPWEAAD 320
Query: 1016 NQT-----CRRCSCHASG------VSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRC 1064
+T CR C C+ V+ E +CD C N G C RC
Sbjct: 321 GKTGAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDD------CQHNTEGQYCQRC 374
Query: 1065 ADGYWN-----LVPGRGCQSCDCDPRTS------QSSHCDQLTGQCPCKLGYGGKRCSEC 1113
G++ C+ C C P S + CD G CPCK G G+RC C
Sbjct: 375 KPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRC 434
Query: 1114 QENYYGDPPGRCIPCDCNRAGTQKPICDPDTGMC 1147
Y+G C PCDC AG+ CDP TG C
Sbjct: 435 MVGYWGFGDYGCRPCDC--AGS----CDPITGDC 462
Score = 94.4 bits (233), Expect = 9e-19
Identities = 55/127 (43%), Positives = 64/127 (50%), Gaps = 19/127 (14%)
Query: 771 CHPQGSVG-SSCSRLGGQCQ-CKPLVVGRCCDRCSTGSY-DLGH-----HGCHPCHCHPQ 822
CH +V +S +R GG C C+ G+ C RC G Y DL C PC CHP
Sbjct: 341 CHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPV 400
Query: 823 GS------KDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFP--SCHPCPCNRFAELCDP 874
GS T CD G CPC V+GRRCDRC+ GY+GF C PC C A CDP
Sbjct: 401 GSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDC---AGSCDP 457
Query: 875 ETGSCFN 881
TG C +
Sbjct: 458 ITGDCIS 464
Score = 75.1 bits (183), Expect = 6e-13
Identities = 52/206 (25%), Positives = 73/206 (35%), Gaps = 40/206 (19%)
Query: 814 CHPCHCHPQGSKDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFP------------SCH 861
C P H V G+C C +G C C Y P C
Sbjct: 271 CIPVHGFRPVKAPGTFHMVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECR 330
Query: 862 PCPCNRFAELCDPET-----------GSCFNCGGFTTGRNCERCIDGYYGNP----SSGQ 906
C CN A+ C + G C +C T G+ C+RC G+Y + S+
Sbjct: 331 TCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPD 390
Query: 907 PCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAP 966
C+PC C P + + S+ C C G G +C C G++G
Sbjct: 391 ACKPCSC--HPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWG---FGDYG 445
Query: 967 CQPCACNNNIDVTDPESCSRVTGECL 992
C+PC C SC +TG+C+
Sbjct: 446 CRPCDCAG--------SCDPITGDCI 463
Score = 74.7 bits (182), Expect = 7e-13
Identities = 46/151 (30%), Positives = 63/151 (41%), Gaps = 32/151 (21%)
Query: 1046 VTGACPCLPNVTGLACDRCADGY----WNLVPGRG-----CQSCDCDPRTSQSSHCD--- 1093
V G C C N G C CA Y W G+ C++C C+ + + H D
Sbjct: 289 VHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGH-ADTCHFDVNV 347
Query: 1094 ------QLTGQCP-CKLGYGGKRCSECQENYYGD------PPGRCIPCDCNRAGT----- 1135
+ G C C+ G+ C C+ +Y D P C PC C+ G+
Sbjct: 348 WEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPA 407
Query: 1136 -QKPICDPDTGMCRCREGVSGQRCDRCARGH 1165
CDP G C C+ GV+G+RCDRC G+
Sbjct: 408 NSVTFCDPSNGDCPCKPGVAGRRCDRCMVGY 438
Score = 69.3 bits (168), Expect = 3e-11
Identities = 34/79 (43%), Positives = 38/79 (48%), Gaps = 12/79 (15%)
Query: 764 DGAVACKCHPQGSVG------SSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHGCHPC 817
D C CHP GS + C G C CKP V GR CDRC G + G +GC PC
Sbjct: 390 DACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPC 449
Query: 818 HCHPQGSKDTVCDQVTGQC 836
C GS CD +TG C
Sbjct: 450 DC--AGS----CDPITGDC 462
Score = 67.4 bits (163), Expect = 1e-10
Identities = 47/155 (30%), Positives = 59/155 (38%), Gaps = 33/155 (21%)
Query: 419 VAGQCLCKENVEGAKCDQCKP--NHYGLSATD-----PLGCQPCDCNPLGSLPFLTCDVD 471
V G+C+CK N G+ C C P N A D P C+ C CN TC D
Sbjct: 289 VHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHAD----TCHFD 344
Query: 472 T-----------GQCL-CLSYVTGAHCEECTVGYWG----LGNHLHGCSPCDCD-IGGAY 514
G C C G +C+ C G++ + C PC C +G A
Sbjct: 345 VNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAV 404
Query: 515 S-----NVCSPKNGQCECRPHVTGRSCSEPAPGYF 544
C P NG C C+P V GR C GY+
Sbjct: 405 LPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYW 439
Score = 64.7 bits (156), Expect = 8e-10
Identities = 51/166 (30%), Positives = 61/166 (36%), Gaps = 43/166 (25%)
Query: 786 GQCQCKPLVVGRCCDRCSTGSYDL------GHHG----CHPCHCHPQGSKDTVCDQVT-- 833
G+C CK G C C+ D G G C C C+ G DT V
Sbjct: 291 GKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCN--GHADTCHFDVNVW 348
Query: 834 --------GQC-PCHGEVSGRRCDRCLAGY-------FGFP-SCHPCPCN---------R 867
G C C G+ C RC G+ F P +C PC C+
Sbjct: 349 EASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPAN 408
Query: 868 FAELCDPETGSCFNCGGFTTGRNCERCIDGYYGNPSSGQPCRPCLC 913
CDP G C C GR C+RC+ GY+G G CRPC C
Sbjct: 409 SVTFCDPSNGDC-PCKPGVAGRRCDRCMVGYWGFGDYG--CRPCDC 451
>gi|145309326 laminin, gamma 1 precursor [Homo sapiens]
Length = 1609
Score = 311 bits (798), Expect = 3e-84
Identities = 256/980 (26%), Positives = 427/980 (43%), Gaps = 171/980 (17%)
Query: 836 CPCHGEVSGRRCDRCLAGYFG-------FPSCHPCPCNRFAELCDPETGSCFNCGGFTTG 888
C C G+ C+ CL+GY + C C CN +E CDPETG C NC T G
Sbjct: 690 CTCPVGYGGQFCEMCLSGYRRETPNLGPYSPCVLCACNGHSETCDPETGVC-NCRDNTAG 748
Query: 889 RNCERCIDGYYGNPSSG--QPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVIC-NCLQGYT 945
+CE+C DGYYG+ ++G C+PC CP SC + +V+C NC G T
Sbjct: 749 PHCEKCSDGYYGDSTAGTSSDCQPCPCPG--------GSSCAVVPKTKEVVCTNCPTGTT 800
Query: 946 GTQCGECSTGFYGNPRISGAP---CQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGAN 1002
G +C C G++G+P P C+ C C++NID +C+R+TGECL+C++NT G
Sbjct: 801 GKRCELCDDGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVGNCNRLTGECLKCIYNTAGFY 860
Query: 1003 CQLCKPGHYGSALNQT----CRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTG 1058
C CK G +G+ L C+ C+C+ G + C+PVTG C CLP+VTG
Sbjct: 861 CDRCKDGFFGNPLAPNPADKCKACNCNLYGTMKQQSS-------CNPVTGQCECLPHVTG 913
Query: 1059 LACDRCADGYWNLVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSECQENYY 1118
C C G++NL G+GC+ CDC S + CD TGQC C+ G G+ C C+ N++
Sbjct: 914 QDCGACDPGFYNLQSGQGCERCDCHALGSTNGQCDIRTGQCECQPGITGQHCERCEVNHF 973
Query: 1119 GDPPGRCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDRCARG--HSQEFPTCLQCH 1176
G P C PCDC+ G+ C D G C CREG G RCD+C +++ +P C +C
Sbjct: 974 GFGPEGCKPCDCHPEGSLSLQC-KDDGRCECREGFVGNRCDQCEENYFYNRSWPGCQECP 1032
Query: 1177 LCFDQWDHTISSLSKAVQGLMRLAANM--EDKRETLPVCEADFKDLRGNVSEIERILKHP 1234
C+ ++ +Q L L AN+ D+ T E K+ V ++ R
Sbjct: 1033 ACYRLVKDKVADHRVKLQELESLIANLGTGDEMVTDQAFEDRLKEAEREVMDLLR----- 1087
Query: 1235 VFPSGKFLKVKDYHDSVRRQIMQLNEQLKA-VYEFQDLKDTIERAKN---EADLLLEDLQ 1290
+ VKD ++ ++ ++N L + + Q++++TIE N +A +E+ +
Sbjct: 1088 -----EAQDVKDVDQNLMDRLQRVNNTLSSQISRLQNIRNTIEETGNLAEQARAHVENTE 1142
Query: 1291 EEIDLQSSVL--------NASIA--DSSENIKKYYHISSSAEK---KINETSSTINTSAN 1337
I++ S L N S+ +S+ + ++ A K + + + I A
Sbjct: 1143 RLIEIASRELEKAKVAAANVSVTQPESTGDPNNMTLLAEEARKLAERHKQEADDIVRVAK 1202
Query: 1338 TRNDLLT-----ILDTLTSKGNLSLERLKQIKIPDIQILNEKVCGDPGNVPCVPLPCGGA 1392
T ND T +L TL + + E I+ LN K
Sbjct: 1203 TANDTSTEAYNLLLRTLAGENQTAFE---------IEELNRKY----------------- 1236
Query: 1393 LCTGRKGHRKCRGPGCHGSLTLSTNALQKAQEAKSIIRNLDKQVRGLKNQIESISEQAEV 1452
++AK+I ++L+KQ + + + ++A
Sbjct: 1237 ------------------------------EQAKNISQDLEKQAARVHEEAKRAGDKAVE 1266
Query: 1453 SKNNALQL----REKLGNIRNQSDSEEENINLFI-KKVKNFL-LEENVPPEDIE------ 1500
+ QL E L N N E EN+ I +K+K++ L E++ +++E
Sbjct: 1267 IYASVAQLSPLDSETLENEANNIKMEAENLEQLIDQKLKDYEDLREDMRGKELEVKNLLE 1326
Query: 1501 --KVANGVLD--IHLPIPSQNLTDELVK-----IQKHMQLCEDYRTDENRLNEEADGAQK 1551
K D + ++ L +E K +Q+ + + + + R+N+ A++
Sbjct: 1327 KGKTEQQTADQLLARADAAKALAEEAAKKGRDTLQEANDILNNLKDFDRRVNDNKTAAEE 1386
Query: 1552 LLVKAKAAEKAANILLNLDKTLNQLQQAQITQGRANSTITQLTAN-----ITKIKKNVLQ 1606
L K A + + ++ + QQA + A++T + A+ + ++KN
Sbjct: 1387 ALRKIPAINQT---ITEANEKTREAQQA-LGSAAADATEAKNKAHEAERIASAVQKNATS 1442
Query: 1607 AENQTREMKSEL-ELAKQRSGLEDGLSLLQTKLQRHQDHAVNAKVQAESAQHQAGSLEKE 1665
+ + +E+ +L + + + L + +L+R QD A + A A A E
Sbjct: 1443 TKAEAERTFAEVTDLDNEVNNMLKQLQEAEKELKRKQDDADQDMMMAGMASQAAQEAEIN 1502
Query: 1666 FVELKKQYAILQRKTSTTGLTKETLGKVKQLKDAAEKLAGDTEAKIR------RITDLER 1719
+ K TS + + L ++ QL + E + +++DL+R
Sbjct: 1503 ARKAKNSV------TSLLSIINDLLEQLGQLDTVDLNKLNEIEGTLNKAKDEMKVSDLDR 1556
Query: 1720 KIQDLNLSRQAKADQLRILE 1739
K+ D L +AK + I++
Sbjct: 1557 KVSD--LENEAKKQEAAIMD 1574
Score = 287 bits (734), Expect = 7e-77
Identities = 166/496 (33%), Positives = 254/496 (51%), Gaps = 66/496 (13%)
Query: 40 NTQLMASSTCGLSRAQKYCILSYLEGEQK-CFICDSRFPYDPYDQPNSHTIENVIVSFEP 98
N ++A++TCG + ++YC+ + + G K C +CD+ QP+ + +
Sbjct: 60 NVTVVATNTCG-TPPEEYCVQTGVTGVTKSCHLCDA-------GQPHLQHGAAFLTDYNN 111
Query: 99 DREKKWWQSENGL------DHVSIRLDLEALFRFSHLILTFKTFRPAAMLVERSTDYGHN 152
+ WWQS+ L +++ L L F +++ L F T RP + + + T
Sbjct: 112 QADTTWWQSQTMLAGVQYPSSINLTLHLGKAFDITYVRLKFHTSRPESFAIYKRTREDGP 171
Query: 153 WKVFKYFAKDCATSFPNITSGQAQGVGD---IVCDSKYSDIEPSTGGEVVLKVLD---PS 206
W ++Y++ C ++ G + GD +C ++SDI P TGG V L+ +
Sbjct: 172 WIPYQYYSGSCENTYSKANRGFIRTGGDEQQALCTDEFSDISPLTGGNVAFSTLEGRPSA 231
Query: 207 FEIENPYSPYIQDLVTLTNLRINFTKLHTLGDALLGRRQNDS--LDKYYYALYEMIVRGS 264
+ +N SP +Q+ VT T++R+ +L+T GD + ND L YYYA+ + V G
Sbjct: 232 YNFDN--SPVLQEWVTATDIRVTLNRLNTFGDEVF----NDPKVLKSYYYAISDFAVGGR 285
Query: 265 CFCNGHASECRPMQKMRGDVFSPPGMVHGQCVCQHNTDGPNCERCKDFFQDAPWRPAADL 324
C CNGHASEC K D C C+HNT G +CE+C FF D PWR A
Sbjct: 286 CKCNGHASEC---MKNEFDKLV--------CNCKHNTYGVDCEKCLPFFNDRPWRRATAE 334
Query: 325 QDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLK 384
+ C C CN S C+FD Y ++G GG C +CQ NT+G HC+RCR F+R
Sbjct: 335 SASECLPCDCNGRSQECYFDPELYRSTG--HGGHCTNCQDNTDGAHCERCRENFFR---- 388
Query: 385 TISDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGL 444
+ + AC C C P G++S C S+ G+C CK V G KCD+C+P + L
Sbjct: 389 -LGNNEACSSCHCSPVGSLSTQ-CDSY---------GRCSCKPGVMGDKCDRCQPGFHSL 437
Query: 445 SATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGL-GNHLHGC 503
+ GC+PC C+P GS+ C+++TG+C+C V G +CE C G++ L ++ GC
Sbjct: 438 TEA---GCRPCSCDPSGSID--ECNIETGRCVCKDNVEGFNCERCKPGFFNLESSNPRGC 492
Query: 504 SPCDCDIGGAYSNVCS 519
+PC C +S+VC+
Sbjct: 493 TPCFC---FGHSSVCT 505
Score = 158 bits (400), Expect = 4e-38
Identities = 100/326 (30%), Positives = 135/326 (41%), Gaps = 73/326 (22%)
Query: 265 CFCNGHASECRPMQKMRGDVFSPPGMVHGQCVCQHNTDGPNCERCKD-FFQDAPWRPAAD 323
C CNGH+ C P G C C+ NT GP+CE+C D ++ D+ ++D
Sbjct: 724 CACNGHSETCDPET--------------GVCNCRDNTAGPHCEKCSDGYYGDSTAGTSSD 769
Query: 324 LQ-----------------DNACRSCSCNSHSSRCHFDMTTYLASG-GLSG--------- 356
Q + C +C + RC Y G +G
Sbjct: 770 CQPCPCPGGSSCAVVPKTKEVVCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQ 829
Query: 357 -----------------GVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDP 399
G C C +NT G +CDRC+ F+ +PL + C C C+
Sbjct: 830 CSDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRCKDGFFGNPLAP-NPADKCKACNCNL 888
Query: 400 DGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNP 459
GT+ + V GQC C +V G C C P Y L + GC+ CDC+
Sbjct: 889 YGTMK-------QQSSCNPVTGQCECLPHVTGQDCGACDPGFYNLQSGQ--GCERCDCHA 939
Query: 460 LGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYSNVCS 519
LGS CD+ TGQC C +TG HCE C V ++G G GC PCDC G+ S C
Sbjct: 940 LGSTNG-QCDIRTGQCECQPGITGQHCERCEVNHFGFGPE--GCKPCDCHPEGSLSLQCK 996
Query: 520 PKNGQCECRPHVTGRSCSEPAPGYFF 545
+G+CECR G C + YF+
Sbjct: 997 D-DGRCECREGFVGNRCDQCEENYFY 1021
Score = 149 bits (376), Expect = 2e-35
Identities = 103/342 (30%), Positives = 137/342 (40%), Gaps = 60/342 (17%)
Query: 767 VACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHG----CHPCHCHPQ 822
V C C+ +C G C C+ G C++CS G Y G C PC C P
Sbjct: 722 VLCACNGHSE---TCDPETGVCNCRDNTAGPHCEKCSDGYYGDSTAGTSSDCQPCPC-PG 777
Query: 823 GS--------KDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFP--------SCHPCPCN 866
GS K+ VC C +G+RC+ C GYFG P C C C+
Sbjct: 778 GSSCAVVPKTKEVVCTN------CPTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQCS 831
Query: 867 -----RFAELCDPETGSCFNCGGFTTGRNCERCIDGYYGNPSSGQP---CRPCLCPDDPS 918
C+ TG C C T G C+RC DG++GNP + P C+ C C
Sbjct: 832 DNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRCKDGFFGNPLAPNPADKCKACNC----- 886
Query: 919 SNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCACNNNIDV 978
N Y + C CL TG CG C GFY SG C+ C C + +
Sbjct: 887 -NLYGTMKQQSSCNPVTGQCECLPHVTGQDCGACDPGFYNLQ--SGQGCERCDC-HALGS 942
Query: 979 TDPESCSRVTGECLRCLHNTQGANCQLCKPGHYGSALNQTCRRCSCHASGVSPMECPPGG 1038
T+ + C TG+C C G +C+ C+ H+G + C+ C CH G ++C
Sbjct: 943 TNGQ-CDIRTGQC-ECQPGITGQHCERCEVNHFGFG-PEGCKPCDCHPEGSLSLQCKD-- 997
Query: 1039 GACLCDPVTGACPCLPNVTGLACDRCADGYWNLVPGRGCQSC 1080
G C C G CD+C + Y+ GCQ C
Sbjct: 998 --------DGRCECREGFVGNRCDQCEENYFYNRSWPGCQEC 1031
Score = 123 bits (309), Expect = 1e-27
Identities = 73/219 (33%), Positives = 105/219 (47%), Gaps = 28/219 (12%)
Query: 332 CSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLK--TISDP 389
C CN H+S C + L VC +C+HNT G C++C P F P + T
Sbjct: 286 CKCNGHASECMKNEFDKL--------VC-NCKHNTYGVDCEKCLPFFNDRPWRRATAESA 336
Query: 390 YACIPCECDPDGTISGGICVSHSDPAL---GSVAGQCL-CKENVEGAKCDQCKPNHYGLS 445
C+PC+C+ G + DP L G C C++N +GA C++C+ N + L
Sbjct: 337 SECLPCDCN------GRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFFRLG 390
Query: 446 ATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGLGNHLHGCSP 505
+ C C C+P+GSL CD G+C C V G C+ C G+ L GC P
Sbjct: 391 NNE--ACSSCHCSPVGSLS-TQCD-SYGRCSCKPGVMGDKCDRCQPGFHSLTEA--GCRP 444
Query: 506 CDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPAPGYF 544
C CD G+ C+ + G+C C+ +V G +C PG+F
Sbjct: 445 CSCDPSGSIDE-CNIETGRCVCKDNVEGFNCERCKPGFF 482
Score = 111 bits (277), Expect = 7e-24
Identities = 70/239 (29%), Positives = 102/239 (42%), Gaps = 34/239 (14%)
Query: 984 CSRVTGECLR---------CLHNTQGANCQLCKPGHYGSALNQTCRRCSCH-ASGVSPME 1033
C+ EC++ C HNT G +C+ C P ++ RR + AS P +
Sbjct: 288 CNGHASECMKNEFDKLVCNCKHNTYGVDCEKCLPFFN----DRPWRRATAESASECLPCD 343
Query: 1034 CPPGGGACLCDPVT-------GACP-CLPNVTGLACDRCADGYWNLVPGRGCQSCDCDPR 1085
C C DP G C C N G C+RC + ++ L C SC C P
Sbjct: 344 CNGRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFFRLGNNEACSSCHCSPV 403
Query: 1086 TSQSSHCDQLTGQCPCKLGYGGKRCSECQENYYGDPPGRCIPCDCNRAGTQKPICDPDTG 1145
S S+ CD G+C CK G G +C CQ ++ C PC C+ +G+ C+ +TG
Sbjct: 404 GSLSTQCDSY-GRCSCKPGVMGDKCDRCQPGFHSLTEAGCRPCSCDPSGSIDE-CNIETG 461
Query: 1146 MCRCREGVSGQRCDRCARG----HSQEFPTCLQC------HLCFDQWDHTISSLSKAVQ 1194
C C++ V G C+RC G S C C +C + +++ S+S Q
Sbjct: 462 RCVCKDNVEGFNCERCKPGFFNLESSNPRGCTPCFCFGHSSVCTNAVGYSVYSISSTFQ 520
Score = 107 bits (267), Expect = 1e-22
Identities = 59/157 (37%), Positives = 79/157 (50%), Gaps = 10/157 (6%)
Query: 764 DGAVACKCHPQGSVG--SSCSRLGGQCQCKPLVVGRCCDRCSTGSYDL-GHHGCHPCHCH 820
D AC C+ G++ SSC+ + GQC+C P V G+ C C G Y+L GC C CH
Sbjct: 879 DKCKACNCNLYGTMKQQSSCNPVTGQCECLPHVTGQDCGACDPGFYNLQSGQGCERCDCH 938
Query: 821 PQGSKDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGF--PSCHPCPCNRFAELC--DPET 876
GS + CD TGQC C ++G+ C+RC +FGF C PC C+ L +
Sbjct: 939 ALGSTNGQCDIRTGQCECQPGITGQHCERCEVNHFGFGPEGCKPCDCHPEGSLSLQCKDD 998
Query: 877 GSCFNCGGFTTGRNCERCIDGYYGNPS--SGQPCRPC 911
G C GF G C++C + Y+ N S Q C C
Sbjct: 999 GRCECREGF-VGNRCDQCEENYFYNRSWPGCQECPAC 1034
Score = 100 bits (248), Expect = 2e-20
Identities = 46/126 (36%), Positives = 61/126 (48%), Gaps = 7/126 (5%)
Query: 749 GACERLIISMSAKLHDGAVACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCSTGSYD 808
GAC+ ++ + G C CH GS C GQC+C+P + G+ C+RC +
Sbjct: 917 GACDPGFYNLQSG--QGCERCDCHALGSTNGQCDIRTGQCECQPGITGQHCERCEVNHFG 974
Query: 809 LGHHGCHPCHCHPQGSKDTVCDQVTGQCPCHGEVSGRRCDRCLAGYF---GFPSCHPCP- 864
G GC PC CHP+GS C G+C C G RCD+C YF +P C CP
Sbjct: 975 FGPEGCKPCDCHPEGSLSLQCKD-DGRCECREGFVGNRCDQCEENYFYNRSWPGCQECPA 1033
Query: 865 CNRFAE 870
C R +
Sbjct: 1034 CYRLVK 1039
Score = 99.0 bits (245), Expect = 4e-20
Identities = 47/120 (39%), Positives = 61/120 (50%), Gaps = 7/120 (5%)
Query: 763 HDGAVACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHGCHPCHCHPQ 822
++ +C C P GS+ + C G +C CKP V+G CDRC G + L GC PC C P
Sbjct: 392 NEACSSCHCSPVGSLSTQCDSYG-RCSCKPGVMGDKCDRCQPGFHSLTEAGCRPCSCDPS 450
Query: 823 GSKDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFPS-----CHPCPCNRFAELCDPETG 877
GS D C+ TG+C C V G C+RC G+F S C PC C + +C G
Sbjct: 451 GSIDE-CNIETGRCVCKDNVEGFNCERCKPGFFNLESSNPRGCTPCFCFGHSSVCTNAVG 509
Score = 97.8 bits (242), Expect = 8e-20
Identities = 53/136 (38%), Positives = 67/136 (49%), Gaps = 9/136 (6%)
Query: 785 GGQC-QCKPLVVGRCCDRCSTGSYDLGHH-GCHPCHCHPQGSKDTVCDQVTGQCPCHGEV 842
GG C C+ G C+RC + LG++ C CHC P GS T CD G+C C V
Sbjct: 364 GGHCTNCQDNTDGAHCERCRENFFRLGNNEACSSCHCSPVGSLSTQCDSY-GRCSCKPGV 422
Query: 843 SGRRCDRCLAGYFGF--PSCHPCPCNRFAEL--CDPETGSCFNCGGFTTGRNCERCIDGY 898
G +CDRC G+ C PC C+ + C+ ETG C C G NCERC G+
Sbjct: 423 MGDKCDRCQPGFHSLTEAGCRPCSCDPSGSIDECNIETGRCV-CKDNVEGFNCERCKPGF 481
Query: 899 YGNPSSG-QPCRPCLC 913
+ SS + C PC C
Sbjct: 482 FNLESSNPRGCTPCFC 497
Score = 96.7 bits (239), Expect = 2e-19
Identities = 65/230 (28%), Positives = 99/230 (43%), Gaps = 40/230 (17%)
Query: 817 CHCHPQGSKDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFP----------SCHPCPCN 866
C C+ S+ + C C G C++CL + P C PC CN
Sbjct: 286 CKCNGHASECMKNEFDKLVCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDCN 345
Query: 867 RFAELC--DPET-------GSCFNCGGFTTGRNCERCIDGYYGNPSSGQPCRPCLC-PDD 916
++ C DPE G C NC T G +CERC + ++ + + C C C P
Sbjct: 346 GRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFF-RLGNNEACSSCHCSPVG 404
Query: 917 PSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCACNNNI 976
S Q ++ C+C G G +C C GF+ ++ A C+PC+C+ +
Sbjct: 405 SLSTQCDSYG----------RCSCKPGVMGDKCDRCQPGFHS---LTEAGCRPCSCDPSG 451
Query: 977 DVTDPESCSRVTGECLRCLHNTQGANCQLCKPGHYG--SALNQTCRRCSC 1024
+ + C+ TG C+ C N +G NC+ CKPG + S+ + C C C
Sbjct: 452 SI---DECNIETGRCV-CKDNVEGFNCERCKPGFFNLESSNPRGCTPCFC 497
Score = 93.2 bits (230), Expect = 2e-18
Identities = 73/247 (29%), Positives = 89/247 (36%), Gaps = 35/247 (14%)
Query: 863 CPCNRFAELCDPETGSCF--NCGGFTTGRNCERCIDGYYGNP------SSGQPCRPCLCP 914
C CN A C NC T G +CE+C+ + P S C PC C
Sbjct: 286 CKCNGHASECMKNEFDKLVCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDC- 344
Query: 915 DDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFY--GNPRISGAPCQPCAC 972
+ S YF Y++ NC G C C F+ GN C C C
Sbjct: 345 NGRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFFRLGN----NEACSSCHC 400
Query: 973 NNNIDVTDPESCSRVTGECLRCLHNTQGANCQLCKPGHYGSALNQTCRRCSCHASGVSPM 1032
+ V + G C C G C C+PG + S CR CSC
Sbjct: 401 S---PVGSLSTQCDSYGRC-SCKPGVMGDKCDRCQPGFH-SLTEAGCRPCSCD------- 448
Query: 1033 ECPPGGGACLCDPVTGACPCLPNVTGLACDRCADGYWNLVPG--RGCQSCDCDPRTSQSS 1090
P G C+ TG C C NV G C+RC G++NL RGC C C SS
Sbjct: 449 ---PSGSIDECNIETGRCVCKDNVEGFNCERCKPGFFNLESSNPRGCTPCFC---FGHSS 502
Query: 1091 HCDQLTG 1097
C G
Sbjct: 503 VCTNAVG 509
Score = 68.9 bits (167), Expect = 4e-11
Identities = 39/126 (30%), Positives = 52/126 (41%), Gaps = 12/126 (9%)
Query: 1049 ACPCLPNVTGLACDRCADGYW----NLVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKLG 1104
+C C G C+ C GY NL P C C C+ S CD TG C C+
Sbjct: 689 SCTCPVGYGGQFCEMCLSGYRRETPNLGPYSPCVLCACN---GHSETCDPETGVCNCRDN 745
Query: 1105 YGGKRCSECQENYYGD----PPGRCIPCDCNRAGTQKPICDPDTGMC-RCREGVSGQRCD 1159
G C +C + YYGD C PC C + + +C C G +G+RC+
Sbjct: 746 TAGPHCEKCSDGYYGDSTAGTSSDCQPCPCPGGSSCAVVPKTKEVVCTNCPTGTTGKRCE 805
Query: 1160 RCARGH 1165
C G+
Sbjct: 806 LCDDGY 811
Score = 67.4 bits (163), Expect = 1e-10
Identities = 44/133 (33%), Positives = 53/133 (39%), Gaps = 13/133 (9%)
Query: 423 CLCKENVEGAKCDQCKPNHYGLSATDPLG----CQPCDCNPLGSLPFLTCDVDTGQCLCL 478
C C G C+ C + T LG C C CN TCD +TG C C
Sbjct: 690 CTCPVGYGGQFCEMCLSGYR--RETPNLGPYSPCVLCACNGHSE----TCDPETGVCNCR 743
Query: 479 SYVTGAHCEECTVGYWG--LGNHLHGCSPCDCDIGGAYSNVCSPKNGQC-ECRPHVTGRS 535
G HCE+C+ GY+G C PC C G + + V K C C TG+
Sbjct: 744 DNTAGPHCEKCSDGYYGDSTAGTSSDCQPCPCPGGSSCAVVPKTKEVVCTNCPTGTTGKR 803
Query: 536 CSEPAPGYFFAPL 548
C GYF PL
Sbjct: 804 CELCDDGYFGDPL 816
Score = 53.9 bits (128), Expect = 1e-06
Identities = 31/94 (32%), Positives = 40/94 (42%), Gaps = 7/94 (7%)
Query: 744 PQVLPGACERLIISMSAKLHDGAVACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCS 803
P V+ C+R + G C C P GS+ C+ G+C CK V G C+RC
Sbjct: 420 PGVMGDKCDRCQPGFHSLTEAGCRPCSCDPSGSI-DECNIETGRCVCKDNVEGFNCERCK 478
Query: 804 TGSYDL---GHHGCHPCHCHPQGSKDTVCDQVTG 834
G ++L GC PC C S VC G
Sbjct: 479 PGFFNLESSNPRGCTPCFCFGHSS---VCTNAVG 509
Score = 51.2 bits (121), Expect = 9e-06
Identities = 28/88 (31%), Positives = 41/88 (46%), Gaps = 2/88 (2%)
Query: 744 PQVLPGACERLIISMSAKLHDGAVACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCS 803
P + CER ++ +G C CHP+GS+ C + G+C+C+ VG CD+C
Sbjct: 958 PGITGQHCERCEVNHFGFGPEGCKPCDCHPEGSLSLQC-KDDGRCECREGFVGNRCDQCE 1016
Query: 804 TG-SYDLGHHGCHPCHCHPQGSKDTVCD 830
Y+ GC C + KD V D
Sbjct: 1017 ENYFYNRSWPGCQECPACYRLVKDKVAD 1044
Score = 47.4 bits (111), Expect = 1e-04
Identities = 71/361 (19%), Positives = 142/361 (39%), Gaps = 66/361 (18%)
Query: 1419 LQKAQEAKSIIRNLDKQVRGLKNQIESISEQAEVSKNNALQLREKLGNIRNQSDSEEENI 1478
L++AQ+ K + +NL +++ + N + S + + +N E+ GN+ Q+ + EN
Sbjct: 1086 LREAQDVKDVDQNLMDRLQRVNNTLSSQISRLQNIRNTI----EETGNLAEQARAHVENT 1141
Query: 1479 NLFIKKVKNFLLEENVPPEDIEKVANGVLDIHLPIPSQN--------LTDELVKI-QKHM 1529
I+ + ++EK ++ + P L +E K+ ++H
Sbjct: 1142 ERLIE----------IASRELEKAKVAAANVSVTQPESTGDPNNMTLLAEEARKLAERHK 1191
Query: 1530 QLCEDYRTDENRLNEEADGAQKLLVKAKAA---------------EKAANILLNLDKTLN 1574
Q +D N+ + A LL++ A E+A NI +L+K
Sbjct: 1192 QEADDIVRVAKTANDTSTEAYNLLLRTLAGENQTAFEIEELNRKYEQAKNISQDLEKQAA 1251
Query: 1575 QLQQAQITQGRANSTITQLTANITKIKKNVLQAENQTREMKSELELAKQRSGLEDGLSLL 1634
++ + G I A ++ + L EN+ +K E E +Q L+
Sbjct: 1252 RVHEEAKRAGDKAVEIYASVAQLSPLDSETL--ENEANNIKMEAENLEQ---------LI 1300
Query: 1635 QTKLQRHQDHAVNAKVQAESAQHQAGSLEKEFVELKKQYAILQRKTSTTGLTKETLGKVK 1694
KL+ ++D + + + ++ LEK E + +L R + L +E K +
Sbjct: 1301 DQKLKDYEDLREDMRGKELEVKN---LLEKGKTEQQTADQLLARADAAKALAEEAAKKGR 1357
Query: 1695 QLKDAAEKLAGDTEAKIRRITDLERKIQDLNLSRQAKADQLRILEDQVVAIKNEIVEQEK 1754
A + + + D +R++ D ++ A + LR ++ AI I E +
Sbjct: 1358 DTLQEANDI-------LNNLKDFDRRVND---NKTAAEEALR----KIPAINQTITEANE 1403
Query: 1755 K 1755
K
Sbjct: 1404 K 1404
>gi|38788416 laminin, alpha 1 precursor [Homo sapiens]
Length = 3075
Score = 289 bits (739), Expect = 2e-77
Identities = 138/340 (40%), Positives = 180/340 (52%), Gaps = 26/340 (7%)
Query: 836 CPCHGEVSGRRCDRCLAGYFGFPS------CHPCPCNRFAELCDPETGSCFNCGGFTTGR 889
C C +G C+ CL+GY+ C PC C+ A C+ G C C TTG
Sbjct: 709 CECPQGYTGTSCESCLSGYYRVDGILFGGICQPCECHGHAAECNVH-GVCIACAHNTTGV 767
Query: 890 NCERCIDGYYGNPSSGQP--CRPCLCPDDPSSNQYFAHSCYQNLWSSDVICN-CLQGYTG 946
+CE+C+ G+YG PS G P C+PC CP +SN F+ +C+ N +V+C+ C GY+G
Sbjct: 768 HCEQCLPGFYGEPSRGTPGDCQPCACPLTIASNN-FSPTCHLND-GDEVVCDWCAPGYSG 825
Query: 947 TQCGECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQLC 1006
C C+ G+YGNP + G C PC C+ N+D ++ C VTGECL+CL NT GA+C+ C
Sbjct: 826 AWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCERC 885
Query: 1007 KPGHYGSALN-QTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCA 1065
G YG A+ + CR C CH G + +C TG C C PNVTG CD+C
Sbjct: 886 ADGFYGDAVTAKNCRACECHVK---------GSHSAVCHLETGLCDCKPNVTGQQCDQCL 936
Query: 1066 DGYWNLVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSECQENYYGDPPGRC 1125
GY+ L G GC+ C+C S S C GQC C G GKRC C +Y G C
Sbjct: 937 HGYYGLDSGHGCRPCNCSVAGSVSDGCTD-EGQCHCVPGVAGKRCDRCAHGFYAYQDGSC 995
Query: 1126 IPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDRCARGH 1165
PCDC + CDP+TG C C G +C+ C GH
Sbjct: 996 TPCDCPHT---QNTCDPETGECVCPPHTQGVKCEECEDGH 1032
Score = 233 bits (593), Expect = 2e-60
Identities = 158/521 (30%), Positives = 246/521 (47%), Gaps = 70/521 (13%)
Query: 35 LLVGRNTQLMASSTCGLSRAQKYC-ILSYLEGEQ----KCFICDSRFPYDPYDQPNSHTI 89
L + N + ++TCG + +C ++ ++ G +C ICD P SH I
Sbjct: 27 LNLASNAHISTNATCGEKGPEMFCKLVEHVPGRPVRNPQCRICDGNSANPRERHPISHAI 86
Query: 90 ENVIVSFEPDREKKWWQS---ENGLDH--VSIRLDLEALFRFSHLILTFKTF-RPAAMLV 143
D WWQS +NG ++ V+I LDL +F+ +++I+ RP ++
Sbjct: 87 ---------DGTNNWWQSPSIQNGREYHWVTITLDLRQVFQVAYVIIKAANAPRPGNWIL 137
Query: 144 ERSTDYGHNWKVFKYFA---KDCATSFPNITSGQA----QGVGDIVCDSKYSDIEPSTGG 196
ERS D G + ++Y+A +C + + NIT + + +++C S YS + P G
Sbjct: 138 ERSLD-GTTFSPWQYYAVSDSECLSRY-NITPRRGPPTYRADDEVICTSYYSRLVPLEHG 195
Query: 197 EVVLKVLDPSFEIENPYSPYIQDLVTLTNLRINFTKLHTLGDAL--LGRRQNDSLD---- 250
E+ +++ ++ SP + + + +R+ ++ TL L L R+ LD
Sbjct: 196 EIHTSLINGRPSADD-LSPKLLEFTSARYIRLRLQRIRTLNADLMTLSHREPKELDPIVT 254
Query: 251 -KYYYALYEMIVRGSCFCNGHASECRPMQKMRGDVFSPPGMVHGQCVCQHNTDGPNCERC 309
+YYY++ ++ V G C C GHAS C P + + QC C+HNT G +C RC
Sbjct: 255 RRYYYSIKDISVGGMCICYGHASSC-PWDETTKKL---------QCQCEHNTCGESCNRC 304
Query: 310 KDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASGGLS-------GGVCEDC 362
+ PWRP N C +C+C++ + C++D + L+ GGVC +C
Sbjct: 305 CPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINC 364
Query: 363 QHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVS---HSDPALGSV 419
NT G +C+ C +YR + + C PC CDP G++S +C+ HSD G
Sbjct: 365 LQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLS-SVCIKDDLHSDLHNGKQ 423
Query: 420 AGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLS 479
GQC CKE G KCD+C+ L D C C CNP+GS C TG C+C
Sbjct: 424 PGQCPCKEGYTGEKCDRCQ-----LGYKDYPTCVSCGCNPVGSASDEPC---TGPCVCKE 475
Query: 480 YVTGAHCEECTVGYWGL-GNHLHGCSPCDCDIGGAYSNVCS 519
V G C+ C G++ L + GCS C C S+VCS
Sbjct: 476 NVEGKACDRCKPGFYNLKEKNPRGCSECFC---FGVSDVCS 513
Score = 199 bits (505), Expect = 3e-50
Identities = 132/409 (32%), Positives = 178/409 (43%), Gaps = 70/409 (17%)
Query: 748 PGACERLI----ISMSAKLHDG-AVACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRC 802
P AC I S + L+DG V C G G+ C R P V G C C
Sbjct: 790 PCACPLTIASNNFSPTCHLNDGDEVVCDWCAPGYSGAWCERCADGYYGNPTVPGESCVPC 849
Query: 803 STGSYDLGHHGCHPCHCHPQGSKDTVCDQVTGQC-PCHGEVSGRRCDRCLAGYFG----F 857
C + S+ CD VTG+C C G G C+RC G++G
Sbjct: 850 D-------------CSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCERCADGFYGDAVTA 896
Query: 858 PSCHPCPCN---RFAELCDPETGSCFNCGGFTTGRNCERCIDGYYGNPSSGQPCRPCLCP 914
+C C C+ + +C ETG C +C TG+ C++C+ GYYG SG CRPC C
Sbjct: 897 KNCRACECHVKGSHSAVCHLETGLC-DCKPNVTGQQCDQCLHGYYG-LDSGHGCRPCNC- 953
Query: 915 DDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCACNN 974
S + C + + C+C+ G G +C C+ GFY C PC C +
Sbjct: 954 ---SVAGSVSDGC-----TDEGQCHCVPGVAGKRCDRCAHGFYA---YQDGSCTPCDCPH 1002
Query: 975 NIDVTDPESCSRVTGECLRCLHNTQGANCQLCKPGHYGSALNQTCRRCSCHASGVSPMEC 1034
+ DPE TGEC+ C +TQG C+ C+ GH+G C+ C+C G +
Sbjct: 1003 TQNTCDPE-----TGECV-CPPHTQGVKCEECEDGHWGYDAEVGCQACNCSLVGSTHHR- 1055
Query: 1035 PPGGGACLCDPVTGACPCLPNVTGLACDRCADGYWNLVPGRGCQSCDCDPRTSQSSHCD- 1093
CD VTG C C G ACD+C+ GY + C CDCD R + C+
Sbjct: 1056 --------CDVVTGHCQCKSKFGGRACDQCSLGYRDF---PDCVPCDCDLRGTSGDACNL 1104
Query: 1094 --------QLTGQCPCKLGYGGKRCSECQENYY---GDPPGRCIPCDCN 1131
+ TG CPCK G +C+EC+E + D P C PC C+
Sbjct: 1105 EQGLCGCVEETGACPCKENVFGPQCNECREGTFALRADNPLGCSPCFCS 1153
Score = 166 bits (419), Expect = 2e-40
Identities = 98/282 (34%), Positives = 140/282 (49%), Gaps = 37/282 (13%)
Query: 265 CFCNGHASECRPMQKMRGDVFSPPGMVHGQCV-CQHNTDGPNCERCKDFFQDAPWRPAAD 323
C C+GHA+EC VHG C+ C HNT G +CE+C F P R
Sbjct: 742 CECHGHAAECN---------------VHGVCIACAHNTTGVHCEQCLPGFYGEPSRGT-- 784
Query: 324 LQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPL 383
C+ C+C + +F T +L G VC+ C G C+RC +Y +P
Sbjct: 785 --PGDCQPCACPLTIASNNFSPTCHLNDG--DEVVCDWCAPGYSGAWCERCADGYYGNP- 839
Query: 384 KTISDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCL-CKENVEGAKCDQCKPNHY 442
T+ +C+PC+C SG + S + SV G+CL C N +GA C++C Y
Sbjct: 840 -TVPGE-SCVPCDC------SGNVDPSEAGHC-DSVTGECLKCLGNTDGAHCERCADGFY 890
Query: 443 GLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGLGNHLHG 502
G A C+ C+C+ GS C ++TG C C VTG C++C GY+GL + HG
Sbjct: 891 G-DAVTAKNCRACECHVKGS-HSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGLDSG-HG 947
Query: 503 CSPCDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPAPGYF 544
C PC+C + G+ S+ C+ + GQC C P V G+ C A G++
Sbjct: 948 CRPCNCSVAGSVSDGCTDE-GQCHCVPGVAGKRCDRCAHGFY 988
Score = 161 bits (408), Expect = 5e-39
Identities = 100/289 (34%), Positives = 134/289 (46%), Gaps = 36/289 (12%)
Query: 768 ACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDL-GHHGCHPCHCHPQGSKD 826
AC+CH +GS + C G C CKP V G+ CD+C G Y L HGC PC+C GS
Sbjct: 901 ACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGLDSGHGCRPCNCSVAGSVS 960
Query: 827 TVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFP--SCHPCPCNRFAELCDPETGSCFNCGG 884
C GQC C V+G+RCDRC G++ + SC PC C CDPETG C C
Sbjct: 961 DGCTD-EGQCHCVPGVAGKRCDRCAHGFYAYQDGSCTPCDCPHTQNTCDPETGECV-CPP 1018
Query: 885 FTTGRNCERCIDGYYGNPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVI---CNCL 941
T G CE C DG++G + C+ C C S++ H C DV+ C C
Sbjct: 1019 HTQGVKCEECEDGHWGYDAE-VGCQACNCSLVGSTH----HRC-------DVVTGHCQCK 1066
Query: 942 QGYTGTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGA 1001
+ G C +CS G+ P C PC C ++ T ++C+ G C C+ T
Sbjct: 1067 SKFGGRACDQCSLGYRDFP-----DCVPCDC--DLRGTSGDACNLEQGLC-GCVEETGAC 1118
Query: 1002 NCQLCKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGAC 1050
CK +G N+ CR + +P+ C P C C ++ C
Sbjct: 1119 P---CKENVFGPQCNE-CREGTFALRADNPLGCSP----CFCSGLSHLC 1159
Score = 157 bits (396), Expect = 1e-37
Identities = 90/258 (34%), Positives = 125/258 (48%), Gaps = 47/258 (18%)
Query: 291 VHGQCV-CQHNTDGPNCERCKD-FFQDAPWRPAADLQDNACRSCSCN---SHSSRCHFDM 345
V G+C+ C NTDG +CERC D F+ DA + CR+C C+ SHS+ CH
Sbjct: 866 VTGECLKCLGNTDGAHCERCADGFYGDA-------VTAKNCRACECHVKGSHSAVCH--- 915
Query: 346 TTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISG 405
L G+C DC+ N GQ CD+C +Y + + C PC C G++S
Sbjct: 916 --------LETGLC-DCKPNVTGQQCDQCLHGYYG-----LDSGHGCRPCNCSVAGSVSD 961
Query: 406 GICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPF 465
G C GQC C V G +CD+C +G A C PCDC +
Sbjct: 962 G-CTDE---------GQCHCVPGVAGKRCDRCA---HGFYAYQDGSCTPCDCPHTQN--- 1005
Query: 466 LTCDVDTGQCLCLSYVTGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYSNVCSPKNGQC 525
TCD +TG+C+C + G CEEC G+WG + GC C+C + G+ + C G C
Sbjct: 1006 -TCDPETGECVCPPHTQGVKCEECEDGHWGYDAEV-GCQACNCSLVGSTHHRCDVVTGHC 1063
Query: 526 ECRPHVTGRSCSEPAPGY 543
+C+ GR+C + + GY
Sbjct: 1064 QCKSKFGGRACDQCSLGY 1081
Score = 147 bits (371), Expect = 9e-35
Identities = 80/252 (31%), Positives = 113/252 (44%), Gaps = 22/252 (8%)
Query: 295 CVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASGGL 354
C C G +CE C + +R L C+ C C+ H++ C+
Sbjct: 709 CECPQGYTGTSCESCLSGY----YRVDGILFGGICQPCECHGHAAECNVH---------- 754
Query: 355 SGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSHSDP 414
GVC C HNT G HC++C P FY +P + P C PC C + H +
Sbjct: 755 --GVCIACAHNTTGVHCEQCLPGFYGEPSR--GTPGDCQPCACPLTIASNNFSPTCHLND 810
Query: 415 ALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNP-LGSLPFLTCDVDTG 473
V C GA C++C +YG C PCDC+ + CD TG
Sbjct: 811 GDEVVCDWCA--PGYSGAWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTG 868
Query: 474 QCL-CLSYVTGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYSNVCSPKNGQCECRPHVT 532
+CL CL GAHCE C G++G C C+C + G++S VC + G C+C+P+VT
Sbjct: 869 ECLKCLGNTDGAHCERCADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLCDCKPNVT 928
Query: 533 GRSCSEPAPGYF 544
G+ C + GY+
Sbjct: 929 GQQCDQCLHGYY 940
Score = 135 bits (341), Expect = 3e-31
Identities = 92/289 (31%), Positives = 117/289 (40%), Gaps = 48/289 (16%)
Query: 765 GAVACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHGCHPCHCHPQGS 824
G A K HP+ V S L C C P VG C C+ G +
Sbjct: 1343 GRKAEKLHPEEEVAS----LLENCVCPPGTVGFSCQDCAPGYH----------------- 1381
Query: 825 KDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFPSCHPCPCNRFAELCDPETGSCFNCGG 884
G+ P + R R L C PC CN ++ CDP TG C NCG
Sbjct: 1382 --------RGKLPAGSD----RGPRPLVA-----PCVPCSCNNHSDTCDPNTGKCLNCGD 1424
Query: 885 FTTGRNCERCIDGYYGN-PSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICN-CLQ 942
T G +C+ C GYYG S C C CP P ++ F+ +C D C+ CL
Sbjct: 1425 NTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPAS--FSPTCVLE-GDHDFRCDACLL 1481
Query: 943 GYTGTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGAN 1002
GY G C CS+ +YGNP+ G CQ C CN + V C R +G+C+ C G
Sbjct: 1482 GYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHG--DCDRTSGQCV-CRLGASGLR 1538
Query: 1003 CQLCKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACP 1051
C C+P H + C C GV + G A L +TG P
Sbjct: 1539 CDECEPRHI--LMETDCVSCDDECVGVLLNDLDEIGDAVLSLNLTGIIP 1585
Score = 134 bits (336), Expect = 1e-30
Identities = 74/208 (35%), Positives = 95/208 (45%), Gaps = 28/208 (13%)
Query: 938 CNCLQGYTGTQCGECSTGFYGN---------PRISGAPCQPCACNNNIDVTDPESCSRVT 988
C C G G C +C+ G++ PR APC PC+CNN+ D DP T
Sbjct: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPN-----T 1416
Query: 989 GECLRCLHNTQGANCQLCKPGHYGSALNQT--CRRCSCHAS---GVSPMECPPGGGACLC 1043
G+CL C NT G +C +C G+YG C C+C S SP G C
Sbjct: 1417 GKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLEGDHDFRC 1476
Query: 1044 DPVTGACPCLPNVTGLACDRCADGYWN--LVPGRGCQSCDCDPRTSQSSHCDQLTGQCPC 1101
D CL G C+RC+ Y+ PG CQ CDC+P S CD+ +GQC C
Sbjct: 1477 DA------CLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQCVC 1530
Query: 1102 KLGYGGKRCSECQENYYGDPPGRCIPCD 1129
+LG G RC EC+ + C+ CD
Sbjct: 1531 RLGASGLRCDECEPRHILMETD-CVSCD 1557
Score = 125 bits (315), Expect = 3e-28
Identities = 183/821 (22%), Positives = 318/821 (38%), Gaps = 128/821 (15%)
Query: 994 CLHNTQGANCQLCKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGAC-----LCDPVTG 1048
C T G +CQ C PG++ L R G P+ P +C CDP TG
Sbjct: 1364 CPPGTVGFSCQDCAPGYHRGKLPAGSDR------GPRPLVAPCVPCSCNNHSDTCDPNTG 1417
Query: 1049 AC-PCLPNVTGLACDRCADGYWNLVPGRG--CQSCDC--DPRTSQSSHCDQLTG----QC 1099
C C N G CD C GY+ V G C C C P S S C L G +C
Sbjct: 1418 KCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSPTC-VLEGDHDFRC 1476
Query: 1100 P-CKLGYGGKRCSECQENYYGDPP---GRCIPCDCNRAGTQKPICDPDTGMCRCREGVSG 1155
C LGY GK C C +YYG+P G C CDCN G+ CD +G C CR G SG
Sbjct: 1477 DACLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGASG 1536
Query: 1156 QRCDRCARGHSQEFPTCLQC-HLCFDQWDHTISSLSKAVQGLMRLAANMEDKRETLPVCE 1214
RCD C H C+ C C + + + AV L+ N+ +PV
Sbjct: 1537 LRCDECEPRHILMETDCVSCDDECVGVLLNDLDEIGDAV-----LSLNLTG---IIPVPY 1588
Query: 1215 ADFKDLRGNVSEI-ERILKHPV---FPSGKFLKVKDYHDSVRRQI-------MQLNEQLK 1263
+L + E +LK + K V + D++++++ ++N +
Sbjct: 1589 GILSNLENTTKYLQESLLKENMQKDLGKIKLEGVAEETDNLQKKLTRMLASTQKVNRATE 1648
Query: 1264 AVY-EFQDLKDTIERAKNEADLLLE--DLQEEIDLQSSVLNASIADSSENIKKYYHISSS 1320
++ E QDL IER + ++E L + +D + N+++ + +N I
Sbjct: 1649 RIFKESQDLAIAIERLQMSITEIMEKTTLNQTLDEDFLLPNSTLQNMQQNGTSLLEIMQI 1708
Query: 1321 AEKKINETSSTINTSANTRNDLLTILDTLTSKGNLSLERLKQIKIPDIQILNEKVCGDPG 1380
+ ++T+ A DLL+ + K LE LK+ + N ++
Sbjct: 1709 RDFTQLHQNATLELKA--AEDLLSQIQENYQKPLEELEVLKEAASHVLSKHNNEL----- 1761
Query: 1381 NVPCVPLPCGGALCTGRKGHRKCRGPGCHGSLTLSTNALQKAQEAKSIIRNLDKQVRGLK 1440
+ L A K QE+ ++ ++ +R
Sbjct: 1762 ----------------------------KAAEALVREAEAKMQESNHLLLMVNANLREFS 1793
Query: 1441 NQIESISEQAEVSKNNALQLREKLGNIRNQSDSEEENINLFIKKVKNFLLEENVPPEDIE 1500
++ + E+ ++ +Q R + Q+D+ ++ + LL
Sbjct: 1794 DKKLHVQEEQNLTSELIVQGRGLIDAAAAQTDAVQDALEHLEDHQDKLLLWS-------A 1846
Query: 1501 KVANGVLDIHLPIPSQNLTDELVKIQKHMQLCEDYRTDENRLNEEA-DGAQKLLVKAKAA 1559
K+ + + D+ + + +N D + + ED+ + RL + G + + + A
Sbjct: 1847 KIRHHIDDLVMHMSQRNAVDLVYR-------AEDHAAEFQRLADVLYSGLENIRNVSLNA 1899
Query: 1560 EKAANILLNLDKTLNQLQQAQITQGRANSTITQLTANITKIKKNVLQAENQTREMKSELE 1619
AA + N+ + + ++ R + + L+ ++ K +Q +R +K
Sbjct: 1900 TSAAYVHYNIQSLIEESEELARDAHRTVTETSLLSESLVSNGKAAVQ--RSSRFLKEGNN 1957
Query: 1620 LAKQRSGLEDGLSLLQTKLQRHQDHAVNAKVQAESAQ----------HQAGSLEKEFVEL 1669
L+++ G+ LS L+ K R Q++AV Q + G+ KE
Sbjct: 1958 LSRKLPGIALELSELRNKTNRFQENAVEITRQTNESLLILRAIPKGIRDKGAKTKELATS 2017
Query: 1670 KKQYAILQRKTSTTGLTKE------TLGKVK-QLKDAAEKLAGDTEAKIRRITDLERKIQ 1722
Q A+ + GL++E +L +V L++ + L T A + RK++
Sbjct: 2018 ASQSAVSTLR-DVAGLSQELLNTSASLSRVNTTLRETHQLLQDSTMATLL----AGRKVK 2072
Query: 1723 DLNLSRQAKADQ---LRILEDQVVAIKNEI---VEQEKKYA 1757
D+ + D+ L++LE+ + +EI + Q +K A
Sbjct: 2073 DVEIQANLLFDRLKPLKMLEENLSRNLSEIKLLISQARKQA 2113
Score = 118 bits (296), Expect = 4e-26
Identities = 78/259 (30%), Positives = 106/259 (40%), Gaps = 76/259 (29%)
Query: 971 ACNNNIDVT---DPESCSRVTGECLRCLHNTQGANCQLCKPGHY---GSALNQTCRRCSC 1024
A +N ID+ D E C C G +C+ C G+Y G C+ C C
Sbjct: 693 ASSNAIDLVVAADVEHCE--------CPQGYTGTSCESCLSGYYRVDGILFGGICQPCEC 744
Query: 1025 H------------------ASGVSPMECPPG-------GGACLCDPVTGACP-------- 1051
H +GV +C PG G C P ACP
Sbjct: 745 HGHAAECNVHGVCIACAHNTTGVHCEQCLPGFYGEPSRGTPGDCQPC--ACPLTIASNNF 802
Query: 1052 ----------------CLPNVTGLACDRCADGYWN--LVPGRGCQSCDC----DPRTSQS 1089
C P +G C+RCADGY+ VPG C CDC DP S++
Sbjct: 803 SPTCHLNDGDEVVCDWCAPGYSGAWCERCADGYYGNPTVPGESCVPCDCSGNVDP--SEA 860
Query: 1090 SHCDQLTGQC-PCKLGYGGKRCSECQENYYGD--PPGRCIPCDCNRAGTQKPICDPDTGM 1146
HCD +TG+C C G C C + +YGD C C+C+ G+ +C +TG+
Sbjct: 861 GHCDSVTGECLKCLGNTDGAHCERCADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGL 920
Query: 1147 CRCREGVSGQRCDRCARGH 1165
C C+ V+GQ+CD+C G+
Sbjct: 921 CDCKPNVTGQQCDQCLHGY 939
Score = 117 bits (293), Expect = 1e-25
Identities = 80/240 (33%), Positives = 105/240 (43%), Gaps = 56/240 (23%)
Query: 993 RCLHNTQGANCQLCKPGHYGS-------ALNQTCRRCSCH---------------ASGVS 1030
+C HNT G +C C PG++ + TC C+CH ++
Sbjct: 291 QCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKSLN 350
Query: 1031 PMECPPGGGACLCDPVTGACPCLPNVTGLACDRCADGYW-----NLVPGRGCQSCDCDPR 1085
GGG C+ CL N G+ C+ C DGY+ + C+ C+CDP
Sbjct: 351 TAGQFRGGGVCI--------NCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPV 402
Query: 1086 TSQSSHC--DQL---------TGQCPCKLGYGGKRCSECQENYYGDPPGRCIPCDCNRAG 1134
S SS C D L GQCPCK GY G++C CQ Y P C+ C CN G
Sbjct: 403 GSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGYKDYP--TCVSCGCNPVG 460
Query: 1135 TQKPICDPDTGMCRCREGVSGQRCDRCARGH---SQEFPT-CLQCHLCFDQWDHTISSLS 1190
+ +P TG C C+E V G+ CDRC G ++ P C +C CF D SSLS
Sbjct: 461 SASD--EPCTGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSEC-FCFGVSD-VCSSLS 516
Score = 103 bits (258), Expect = 1e-21
Identities = 68/235 (28%), Positives = 102/235 (43%), Gaps = 36/235 (15%)
Query: 332 CSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLK--TISDP 389
C C H+S C +D TT C+ C+HNT G+ C+RC P +++ P + T+S
Sbjct: 270 CICYGHASSCPWDETTKKLQ-------CQ-CEHNTCGESCNRCCPGYHQQPWRPGTVSSG 321
Query: 390 YACIPCECDPDGT-ISGGICVSHSDPALGSVA-----GQCL-CKENVEGAKCDQCKPNHY 442
C C C V+ +L + G C+ C +N G C+ C +Y
Sbjct: 322 NTCEACNCHNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYY 381
Query: 443 GLSATDPLG---CQPCDCNPLGSLPFLTCDVDT----------GQCLCLSYVTGAHCEEC 489
P C+PC+C+P+GSL + D GQC C TG C+ C
Sbjct: 382 RPHKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRC 441
Query: 490 TVGYWGLGNHLHGCSPCDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPAPGYF 544
+GY C C C+ G+ S+ P G C C+ +V G++C PG++
Sbjct: 442 QLGY----KDYPTCVSCGCNPVGSASD--EPCTGPCVCKENVEGKACDRCKPGFY 490
Score = 102 bits (254), Expect = 3e-21
Identities = 72/242 (29%), Positives = 93/242 (38%), Gaps = 47/242 (19%)
Query: 924 AHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNP-----RISGAPCQPCACNNNI-D 977
A SC + + + C C G C C G++ P SG C+ C C+N D
Sbjct: 276 ASSCPWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKD 335
Query: 978 VTDPESCS------------RVTGECLRCLHNTQGANCQLCKPGHY-----GSALNQTCR 1020
ES + R G C+ CL NT G NC+ C G+Y ++ CR
Sbjct: 336 CYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCR 395
Query: 1021 RCSCHASGVSPMECPPGGGACLCDPV---------TGACPCLPNVTGLACDRCADGYWNL 1071
C+C G C+ D + G CPC TG CDRC GY +
Sbjct: 396 PCNCDPVGSL-------SSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGYKDY 448
Query: 1072 VPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSECQENYYG---DPPGRCIPC 1128
C SC C+P S S + TG C CK GK C C+ +Y P C C
Sbjct: 449 PT---CVSCGCNPVGSASD--EPCTGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSEC 503
Query: 1129 DC 1130
C
Sbjct: 504 FC 505
Score = 100 bits (250), Expect = 1e-20
Identities = 66/199 (33%), Positives = 84/199 (42%), Gaps = 22/199 (11%)
Query: 295 CVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNA----CRSCSCNSHSSRCHFDMTTYLA 350
CVC T G +C+ C + +D C CSCN+HS C D T
Sbjct: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTC--DPNT--- 1416
Query: 351 SGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVS 410
G C +C NT G HCD C +Y + SD C C P + S CV
Sbjct: 1417 ------GKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCA-CPHSPPASFSP-TCVL 1468
Query: 411 HSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDV 470
D A C EG C++C ++YG T CQ CDCNP GS+ CD
Sbjct: 1469 EGDHDFRCDA----CLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSV-HGDCDR 1523
Query: 471 DTGQCLCLSYVTGAHCEEC 489
+GQC+C +G C+EC
Sbjct: 1524 TSGQCVCRLGASGLRCDEC 1542
Score = 99.0 bits (245), Expect = 4e-20
Identities = 70/228 (30%), Positives = 93/228 (40%), Gaps = 41/228 (17%)
Query: 882 CGGFTTGRNCERCIDGYYGNP------SSGQPCRPCLCP--------DDPSSNQYFAHSC 927
C T G +C RC GY+ P SSG C C C D+ + Q + +
Sbjct: 292 CEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKSLNT 351
Query: 928 YQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRIS---GAPCQPCACNNNIDVTDPESC 984
V NCLQ G C C G+Y ++S PC+PC C D S
Sbjct: 352 AGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNC----DPVGSLSS 407
Query: 985 SRVTGECLRCLHNTQGANCQLCKPGHYGSALNQTCRRC--------SCHASGVSPMECPP 1036
+ + LHN + CK G+ G + C RC +C + G +P+
Sbjct: 408 VCIKDDLHSDLHNGKQPGQCPCKEGYTG----EKCDRCQLGYKDYPTCVSCGCNPV---- 459
Query: 1037 GGGACLCDPVTGACPCLPNVTGLACDRCADGYWNLVP--GRGCQSCDC 1082
G+ +P TG C C NV G ACDRC G++NL RGC C C
Sbjct: 460 --GSASDEPCTGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSECFC 505
Score = 97.1 bits (240), Expect = 1e-19
Identities = 64/174 (36%), Positives = 88/174 (50%), Gaps = 30/174 (17%)
Query: 293 GQCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCH-FDMTTYLAS 351
G+CVC +T G CE C +D W A++ C++C+C+ S H D+ T
Sbjct: 1012 GECVCPPHTQGVKCEEC----EDGHWGYDAEV---GCQACNCSLVGSTHHRCDVVT---- 1060
Query: 352 GGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSH 411
G C+ C+ G+ CD+C L YRD D C+PC+CD GT SG C +
Sbjct: 1061 -----GHCQ-CKSKFGGRACDQCS-LGYRD----FPD---CVPCDCDLRGT-SGDAC-NL 1104
Query: 412 SDPALGSV--AGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSL 463
G V G C CKENV G +C++C+ + L A +PLGC PC C+ L L
Sbjct: 1105 EQGLCGCVEETGACPCKENVFGPQCNECREGTFALRADNPLGCSPCFCSGLSHL 1158
Score = 87.4 bits (215), Expect = 1e-16
Identities = 51/151 (33%), Positives = 65/151 (43%), Gaps = 21/151 (13%)
Query: 783 RLGGQC-QCKPLVVGRCCDRCSTGSY------DLGHHGCHPCHCHPQGSKDTVC------ 829
R GG C C +G C+ C G Y C PC+C P GS +VC
Sbjct: 356 RGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLH 415
Query: 830 -----DQVTGQCPCHGEVSGRRCDRCLAGYFGFPSCHPCPCNRFAELCD-PETGSCFNCG 883
+ GQCPC +G +CDRC GY +P+C C CN D P TG C C
Sbjct: 416 SDLHNGKQPGQCPCKEGYTGEKCDRCQLGYKDYPTCVSCGCNPVGSASDEPCTGPCV-CK 474
Query: 884 GFTTGRNCERCIDGYYG-NPSSGQPCRPCLC 913
G+ C+RC G+Y + + C C C
Sbjct: 475 ENVEGKACDRCKPGFYNLKEKNPRGCSECFC 505
Score = 87.0 bits (214), Expect = 1e-16
Identities = 59/200 (29%), Positives = 85/200 (42%), Gaps = 39/200 (19%)
Query: 265 CFCNGHASECRPMQKMRGDVFSPPGMVHGQCV-CQHNTDGPNCERCKDFFQDAPWRPAAD 323
C CN H+ C P G+C+ C NT G +C+ C + A+D
Sbjct: 1403 CSCNNHSDTCDPNT--------------GKCLNCGDNTAGDHCDVCTSGYYGKVTGSASD 1448
Query: 324 LQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPL 383
C C+C HS F T L G C+ C EG+HC+RC +Y +P
Sbjct: 1449 -----CALCAC-PHSPPASFSPTCVLE--GDHDFRCDACLLGYEGKHCERCSSSYYGNPQ 1500
Query: 384 KTISDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYG 443
+ +C C+C+P G++ G +GQC+C+ G +CD+C+P H
Sbjct: 1501 ---TPGGSCQKCDCNPHGSVHGDC---------DRTSGQCVCRLGASGLRCDECEPRHI- 1547
Query: 444 LSATDPLGCQPCDCNPLGSL 463
L TD C CD +G L
Sbjct: 1548 LMETD---CVSCDDECVGVL 1564
Score = 86.7 bits (213), Expect = 2e-16
Identities = 61/193 (31%), Positives = 76/193 (39%), Gaps = 25/193 (12%)
Query: 362 CQHNTEGQHCDRCRPLFYRDPLKTISDP------YACIPCECDPDGTISGGICVSHSDPA 415
C T G C C P ++R L SD C+PC C+ +HSD
Sbjct: 1364 CPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCN-----------NHSDTC 1412
Query: 416 LGSVAGQCL-CKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFL-TC----D 469
+ G+CL C +N G CD C +YG C C C F TC D
Sbjct: 1413 DPNT-GKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLEGD 1471
Query: 470 VDTGQCLCLSYVTGAHCEECTVGYWGLGNHLHG-CSPCDCDIGGAYSNVCSPKNGQCECR 528
D CL G HCE C+ Y+G G C CDC+ G+ C +GQC CR
Sbjct: 1472 HDFRCDACLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQCVCR 1531
Query: 529 PHVTGRSCSEPAP 541
+G C E P
Sbjct: 1532 LGASGLRCDECEP 1544
Score = 82.0 bits (201), Expect = 5e-15
Identities = 43/122 (35%), Positives = 54/122 (44%), Gaps = 16/122 (13%)
Query: 765 GAVACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHGCHPCHCHPQGS 824
G AC C GS C + G CQCK GR CD+CS G D C PC C +G+
Sbjct: 1040 GCQACNCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLGYRDF--PDCVPCDCDLRGT 1097
Query: 825 KDTVCD---------QVTGQCPCHGEVSGRRCDRCLAGYFGFPS-----CHPCPCNRFAE 870
C+ + TG CPC V G +C+ C G F + C PC C+ +
Sbjct: 1098 SGDACNLEQGLCGCVEETGACPCKENVFGPQCNECREGTFALRADNPLGCSPCFCSGLSH 1157
Query: 871 LC 872
LC
Sbjct: 1158 LC 1159
Score = 79.3 bits (194), Expect = 3e-14
Identities = 50/191 (26%), Positives = 76/191 (39%), Gaps = 56/191 (29%)
Query: 1038 GGACLCDPVTGACP-----------CLPNVTGLACDRCADGY----W---NLVPGRGCQS 1079
GG C+C +CP C N G +C+RC GY W + G C++
Sbjct: 267 GGMCICYGHASSCPWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEA 326
Query: 1080 CDCDPRTSQSSHCDQLTGQ----------------CPCKLGYGGKRCSECQENY------ 1117
C+C + + + + Q C G C C + Y
Sbjct: 327 CNCHNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKV 386
Query: 1118 --YGDPPGRCIPCDCNRAGTQKPICDPD-----------TGMCRCREGVSGQRCDRCARG 1164
Y D P C PC+C+ G+ +C D G C C+EG +G++CDRC G
Sbjct: 387 SPYEDEP--CRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLG 444
Query: 1165 HSQEFPTCLQC 1175
+ +++PTC+ C
Sbjct: 445 Y-KDYPTCVSC 454
Score = 72.8 bits (177), Expect = 3e-12
Identities = 42/121 (34%), Positives = 52/121 (42%), Gaps = 22/121 (18%)
Query: 769 CKCHPQGSVGSSC-----------SRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHGCHPC 817
C C P GS+ S C + GQC CK G CDRC G D + C C
Sbjct: 397 CNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGYKD--YPTCVSC 454
Query: 818 HCHPQGS-KDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFP-----SCHPCPCNRFAEL 871
C+P GS D C TG C C V G+ CDRC G++ C C C +++
Sbjct: 455 GCNPVGSASDEPC---TGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSECFCFGVSDV 511
Query: 872 C 872
C
Sbjct: 512 C 512
Score = 68.9 bits (167), Expect = 4e-11
Identities = 58/227 (25%), Positives = 73/227 (32%), Gaps = 87/227 (38%)
Query: 835 QCPCHGEVSGRRCDRCLAGYFGFP----------SCHPCPCNRFAELCDPET-------- 876
QC C G C+RC GY P +C C C+ A+ C +
Sbjct: 289 QCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKS 348
Query: 877 ----------GSCFNCGGFTTGRNCERCIDGYYG----NPSSGQPCRPCLCPDDPSSNQY 922
G C NC T G NCE CIDGYY +P +PCRPC C DP +
Sbjct: 349 LNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNC--DPVGS-- 404
Query: 923 FAHSCYQNLWSSDVI-------CNCLQGYTGTQCGECS---------------------- 953
+ C ++ SD+ C C +GYTG +C C
Sbjct: 405 LSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGYKDYPTCVSCGCNPVGSASD 464
Query: 954 ----------------------TGFYGNPRISGAPCQPCACNNNIDV 978
GFY + C C C DV
Sbjct: 465 EPCTGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSECFCFGVSDV 511
Score = 63.5 bits (153), Expect = 2e-09
Identities = 42/136 (30%), Positives = 61/136 (44%), Gaps = 16/136 (11%)
Query: 423 CLCKENVEGAKCDQCKPNHYGLSATDPLG-CQPCDCNPLGSLPFLTCDVDTGQCL-CLSY 480
C C + G C+ C +Y + G CQPC+C+ + C+V G C+ C
Sbjct: 709 CECPQGYTGTSCESCLSGYYRVDGILFGGICQPCECHGHAA----ECNVH-GVCIACAHN 763
Query: 481 VTGAHCEECTVGYWGLGNH--LHGCSPCDCDIGGAYSN---VCSPKNGQ---CE-CRPHV 531
TG HCE+C G++G + C PC C + A +N C +G C+ C P
Sbjct: 764 TTGVHCEQCLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPGY 823
Query: 532 TGRSCSEPAPGYFFAP 547
+G C A GY+ P
Sbjct: 824 SGAWCERCADGYYGNP 839
Score = 52.8 bits (125), Expect = 3e-06
Identities = 39/137 (28%), Positives = 54/137 (39%), Gaps = 15/137 (10%)
Query: 466 LTCDVDTGQCLCLSYVTGAHCEECTVGYWGLGNHLHG--CSPCDCDIGGAYSNVCSPKNG 523
L D C C TG CE C GY+ + L G C PC+C A NV +G
Sbjct: 700 LVVAADVEHCECPQGYTGTSCESCLSGYYRVDGILFGGICQPCECHGHAAECNV----HG 755
Query: 524 QC-ECRPHVTGRSCSEPAPGYFFAPLNFYLYEAEEATTLQGLAPLGSETFGQSPAVHVVL 582
C C + TG C + PG++ P + + PL + SP H+
Sbjct: 756 VCIACAHNTTGVHCEQCLPGFYGEPSRGTPGDCQPCA-----CPLTIASNNFSPTCHLND 810
Query: 583 GEPVPGNPVTWTGPGFA 599
G+ V W PG++
Sbjct: 811 GDEV---VCDWCAPGYS 824
Score = 50.8 bits (120), Expect = 1e-05
Identities = 30/98 (30%), Positives = 39/98 (39%), Gaps = 17/98 (17%)
Query: 1095 LTGQCPCKLGYGGKRCSECQENYY----------GDPP--GRCIPCDCNRAGTQKPICDP 1142
L C C G G C +C Y+ G P C+PC CN CDP
Sbjct: 1358 LLENCVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCN---NHSDTCDP 1414
Query: 1143 DTGMC-RCREGVSGQRCDRCARG-HSQEFPTCLQCHLC 1178
+TG C C + +G CD C G + + + C LC
Sbjct: 1415 NTGKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALC 1452
>gi|21264602 laminin alpha 5 [Homo sapiens]
Length = 3695
Score = 285 bits (730), Expect = 2e-76
Identities = 184/598 (30%), Positives = 273/598 (45%), Gaps = 93/598 (15%)
Query: 7 LFLHLGWLSYSKAQDDCNRG-ACHPTTGDLLVGRNTQLMASSTCGLSRAQK--------- 56
L + L L ++A+++ G + HP +L G ++ AS+TCG +
Sbjct: 23 LLVGLALLGAARAREEAGGGFSLHPPYFNLAEG--ARIAASATCGEEAPARGSPRPTEDL 80
Query: 57 YCIL-----------SYLEGEQKCFICDSRFPYDPYDQPNSHTIENVIVSFEPDREKKWW 105
YC L + G Q C IC + + +H N I D ++WW
Sbjct: 81 YCKLVGGPVAGGDPNQTIRG-QYCDICTAA------NSNKAHPASNAI-----DGTERWW 128
Query: 106 QS---ENGLDH--VSIRLDLEALFRFSHLILTFKTF-RPAAMLVERSTDYGHNWKVFKYF 159
QS GL++ V++ LDL +F +++++ F RP ++ERS D+G ++ +++F
Sbjct: 129 QSPPLSRGLEYNEVNVTLDLGQVFHVAYVLIKFANSPRPDLWVLERSMDFGRTYQPWQFF 188
Query: 160 A---KDCATSFPNITSGQAQGVGDIVCDSKYSDIEPSTGGEVVLKVLDPSFEIEN-PYSP 215
A +DC F T + +C ++YS I P GE+V+ +++ N YSP
Sbjct: 189 ASSKRDCLERFGPQTLERITRDDAAICTTEYSRIVPLENGEIVVSLVNGRPGAMNFSYSP 248
Query: 216 YIQDLVTLTNLRINFTKLHTLGDALLGRRQNDSL--DKYYYALYEMIVRGSCFCNGHASE 273
+++ TN+R+ F + +TL L+G+ D +YYY++ ++ + G C C+GHA
Sbjct: 249 LLREFTKATNVRLRFLRTNTLLGHLMGKALRDPTVTRRYYYSIKDISIGGRCVCHGHADA 308
Query: 274 CRPMQKMRGDVFSPPGMVHGQCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCS 333
C D P QC CQHNT G C+RC F PW+PA N C+SC+
Sbjct: 309 C--------DAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCN 360
Query: 334 CNSHSSRCHFD--MTTYLASGGL-----SGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTI 386
C H++ C++D + AS L GGVC DCQH+T G +C+RC P FYR P +
Sbjct: 361 CYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPL 420
Query: 387 SDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSA 446
P+ C C C+ D T D + G+C C+ N G +CD C G +
Sbjct: 421 DSPHVCRRCNCESDFT----------DGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFPS 470
Query: 447 TDPLGCQP---------------CDCNPLGSL-PFLTCDVDTGQCLCLSYVTGAHCEECT 490
P CDC+ G+ D G+CLC G HCE C
Sbjct: 471 CYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCA 530
Query: 491 VGYWGLGNHLHGCSPCDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPAPGYFFAPL 548
G++G GC PC C G + C P GQC CR G +C APGYF PL
Sbjct: 531 PGFYG-----PGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPL 583
Score = 248 bits (632), Expect = 5e-65
Identities = 145/411 (35%), Positives = 186/411 (45%), Gaps = 48/411 (11%)
Query: 767 VACKCHPQGSVGSSCSR--LGGQCQCKPLVVGRCCDRCSTGSYDLGHHGCHPCHCHPQGS 824
V C C G+ G++C + G+C CKP G C+ C+ G Y GC PC C G
Sbjct: 492 VNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCAPGFYG---PGCQPCQCSSPGV 548
Query: 825 KDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFPSCHPCPCN---RFAELCDPETGSCFN 881
D CD TGQC C G CDRC GYF FP C C C+ E CD E G C
Sbjct: 549 ADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPLCQLCGCSPAGTLPEGCD-EAGRCL- 606
Query: 882 CGGFTTGRNCERCIDGYYGNPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCL 941
C G +C+RC GY+G P+ C+ C C DP L + +C C
Sbjct: 607 CQPEFAGPHCDRCRPGYHGFPN----CQACTC--DP-------RGALDQLCGAGGLCRCR 653
Query: 942 QGYTGTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGA 1001
GYTGT C ECS GF+G P C PC C + + + +C +G+C C G
Sbjct: 654 PGYTGTACQECSPGFHGFP-----SCVPCHC--SAEGSLHAACDPRSGQC-SCRPRVTGL 705
Query: 1002 NCQLCKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLAC 1061
C C PG Y C SCH +G++P++ C C +V G +C
Sbjct: 706 RCDTCVPGAYNFPY---CEAGSCHPAGLAPVD-------PALPEAQVPCMCRAHVEGPSC 755
Query: 1062 DRCADGYWNLVPG--RGCQSCDCDPRTSQS--SHCDQLTGQCPCKLGYGGKRCSECQENY 1117
DRC G+W L P GC C CD R + + C TGQC CK G+ C+ C++ +
Sbjct: 756 DRCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGF 815
Query: 1118 YGDPPG---RCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDRCARGH 1165
+G C C C+ G C+P TG+CRCR G C AR H
Sbjct: 816 FGLDQADYFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPARDH 866
Score = 246 bits (627), Expect = 2e-64
Identities = 142/425 (33%), Positives = 191/425 (44%), Gaps = 53/425 (12%)
Query: 836 CPCHGEVSGRRCDRCLAGYFG------FPSCHPCPCNRFAELCDPETGSCFNCGGFTTGR 889
C C G C C G++ C PC C+ ++ C P +G C +C T G
Sbjct: 1831 CLCPASYRGDSCQECAPGFYRDVKGLFLGRCVPCQCHGHSDRCLPGSGVCVDCQHNTEGA 1890
Query: 890 NCERCIDGYYGNPSS-GQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQ 948
+CERC G+ + PC C CP SN FA C L C C GY G
Sbjct: 1891 HCERCQAGFVSSRDDPSAPCVSCPCPLSVPSNN-FAEGCV--LRGGRTQCLCKPGYAGAS 1947
Query: 949 CGECSTGFYGNPRISGAPCQPCACNNNIDVTDP----ESCSRVTGECLRCLHNTQGANCQ 1004
C C+ GF+GNP + G+ CQPC C+ N DP C +TG C CL +T G C+
Sbjct: 1948 CERCAPGFFGNPLVLGSSCQPCDCSGN---GDPNLLFSDCDPLTGACRGCLRHTTGPRCE 2004
Query: 1005 LCKPGHYGSA-LNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDR 1063
+C PG YG+A L C RC C G CDP +G C C VTG CDR
Sbjct: 2005 ICAPGFYGNALLPGNCTRCDCTPCGTE-----------ACDPHSGHCLCKAGVTGRRCDR 2053
Query: 1064 CADGYWNLVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSECQENYYGDPPG 1123
C +G++ GC+ C C P ++ S C +GQC C+ G G +C EC Y+G P
Sbjct: 2054 CQEGHFGFDGCGGCRPCACGP-AAEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGLPEQ 2112
Query: 1124 RCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDRCARGHSQEFP-----TCLQCHLC 1178
C C C CDP TG C C G+SG+RCD C++ H P + C +C
Sbjct: 2113 GCRRCQCPGGR-----CDPHTGRCNCPPGLSGERCDTCSQQHQVPVPGGPVGHSIHCEVC 2167
Query: 1179 FDQWDHTISSLSKAVQGLMRLAANMEDKRETL------PVCEADFKDLRGNVSEIERILK 1232
DH + L + L R A + E L + A L ++++++ L+
Sbjct: 2168 ----DHCVVLL---LDDLERAGALLPAIHEQLRGINASSMAWARLHRLNASIADLQSQLR 2220
Query: 1233 HPVFP 1237
P+ P
Sbjct: 2221 SPLGP 2225
Score = 201 bits (510), Expect = 7e-51
Identities = 141/456 (30%), Positives = 175/456 (38%), Gaps = 109/456 (23%)
Query: 808 DLGHHGCHPCHCHPQG--SKDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFP------- 858
D+ G CH H +KD D QC C G CDRC G+ P
Sbjct: 293 DISIGGRCVCHGHADACDAKDPT-DPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATAN 351
Query: 859 ---SCHPCPCNRFAELC--DPET----------------GSCFNCGGFTTGRNCERCIDG 897
C C C A C DPE G C +C TTG NCERC+ G
Sbjct: 352 SANECQSCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPG 411
Query: 898 YYGNPS----SGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECS 953
+Y +P+ S CR C C D F ++L C C ++G +C C+
Sbjct: 412 FYRSPNHPLDSPHVCRRCNCESD------FTDGTCEDLTGR---CYCRPNFSGERCDVCA 462
Query: 954 TGFYGNPRISGAPC-------------QPCACNNNIDVTDPESCSR--VTGECLRCLHNT 998
GF G P P Q C+ + T +C + G CL C N
Sbjct: 463 EGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCL-CKPNF 521
Query: 999 QGANCQLCKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACL---------------- 1042
QG +C+LC PG YG C+ C C + GV+ C P G C
Sbjct: 522 QGTHCELCAPGFYGPG----CQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCAPG 577
Query: 1043 -----------CDPV---------TGACPCLPNVTGLACDRCADGYWNLVPGRGCQSCDC 1082
C P G C C P G CDRC GY CQ+C C
Sbjct: 578 YFHFPLCQLCGCSPAGTLPEGCDEAGRCLCQPEFAGPHCDRCRPGYHGF---PNCQACTC 634
Query: 1083 DPRTSQSSHCDQLTGQCPCKLGYGGKRCSECQENYYGDPPGRCIPCDCNRAGTQKPICDP 1142
DPR + C G C C+ GY G C EC ++G P C+PC C+ G+ CDP
Sbjct: 635 DPRGALDQLCG-AGGLCRCRPGYTGTACQECSPGFHGFP--SCVPCHCSAEGSLHAACDP 691
Query: 1143 DTGMCRCREGVSGQRCDRCARGHSQEFPTCL--QCH 1176
+G C CR V+G RCD C G + FP C CH
Sbjct: 692 RSGQCSCRPRVTGLRCDTCVPG-AYNFPYCEAGSCH 726
Score = 184 bits (467), Expect = 7e-46
Identities = 123/424 (29%), Positives = 181/424 (42%), Gaps = 86/424 (20%)
Query: 293 GQCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASG 352
G+C+CQ GP+C+RC+ + P C++C+C+ + L
Sbjct: 603 GRCLCQPEFAGPHCDRCRPGYHGFP----------NCQACTCDPRGA---------LDQL 643
Query: 353 GLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTI--------- 403
+GG+C C+ G C C P F+ P +C+PC C +G++
Sbjct: 644 CGAGGLCR-CRPGYTGTACQECSPGFHGFP--------SCVPCHCSAEGSLHAACDPRSG 694
Query: 404 --------------------------SGGIC----VSHSDPALGSVAGQCLCKENVEGAK 433
G C ++ DPAL C+C+ +VEG
Sbjct: 695 QCSCRPRVTGLRCDTCVPGAYNFPYCEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPS 754
Query: 434 CDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLT-CDVDTGQCLCLSYVTGAHCEECTVG 492
CD+CKP +GLS ++P GC C C+ G+L + C TGQC C +V G C C G
Sbjct: 755 CDRCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDG 814
Query: 493 YWGLGN-HLHGCSPCDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPAPGYFFAPLNFY 551
++GL GC C CDIGGA C P+ G C CRP+ G +CSEPA ++ L+
Sbjct: 815 FFGLDQADYFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPARDHYLPDLHHL 874
Query: 552 LYEAEEATTLQGLAPLGSETFGQSPAVHVVLGEPVPGNPVTWTGPGFARVLPGAGLRFAV 611
E EEA T +G A FG + P+ +W G+A++ P A
Sbjct: 875 RLELEEAATPEGHA----VRFGFN---------PLEFENFSWR--GYAQMAPVQPRIVAR 919
Query: 612 NNIPFPVDFTIAIHYETQSAADWTVQIVVNPPGGSEHCIPKTLQSKPQSFALPAATRIML 671
N+ P F + Y + A + ++ V G S C T QS+P +F P +T
Sbjct: 920 LNLTSPDLFWLVFRYVNRGAMSVSGRVSVREEGRSATCANCTAQSQPVAF--PPSTEPAF 977
Query: 672 LPTP 675
+ P
Sbjct: 978 ITVP 981
Score = 165 bits (417), Expect = 4e-40
Identities = 96/261 (36%), Positives = 126/261 (48%), Gaps = 27/261 (10%)
Query: 931 LWSSDVICNCLQGYTGTQCGECSTGFYGNPR-ISGAPCQPCACNNNIDVTDPESCSRVTG 989
L S+ +C C Y G C EC+ GFY + + + C PC C+ + D C +G
Sbjct: 1824 LASNVELCLCPASYRGDSCQECAPGFYRDVKGLFLGRCVPCQCHGHSD-----RCLPGSG 1878
Query: 990 ECLRCLHNTQGANCQLCKPGHYGSALNQT--CRRCSCHASGVSPMECPPGGGA--CLCDP 1045
C+ C HNT+GA+C+ C+ G S + + C C C P+ P A C+
Sbjct: 1879 VCVDCQHNTEGAHCERCQAGFVSSRDDPSAPCVSCPC------PLSVPSNNFAEGCVLRG 1932
Query: 1046 VTGACPCLPNVTGLACDRCADGYWN--LVPGRGCQSCDCDPRTSQS---SHCDQLTGQC- 1099
C C P G +C+RCA G++ LV G CQ CDC + S CD LTG C
Sbjct: 1933 GRTQCLCKPGYAGASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACR 1992
Query: 1100 PCKLGYGGKRCSECQENYYGDP--PGRCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQR 1157
C G RC C +YG+ PG C CDC GT+ CDP +G C C+ GV+G+R
Sbjct: 1993 GCLRHTTGPRCEICAPGFYGNALLPGNCTRCDCTPCGTE--ACDPHSGHCLCKAGVTGRR 2050
Query: 1158 CDRCARGHSQEFPTCLQCHLC 1178
CDRC GH F C C C
Sbjct: 2051 CDRCQEGHF-GFDGCGGCRPC 2070
Score = 160 bits (404), Expect = 1e-38
Identities = 100/284 (35%), Positives = 131/284 (46%), Gaps = 38/284 (13%)
Query: 265 CFCNGHASECRPMQKMRGDVFSPPGMVHGQCV-CQHNTDGPNCERCKDFFQDAPWRPAAD 323
C C+GH+ C P G CV CQHNT+G +CERC+ F + P+A
Sbjct: 1864 CQCHGHSDRCLPGS--------------GVCVDCQHNTEGAHCERCQAGFVSSRDDPSAP 1909
Query: 324 LQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPL 383
C SC C +F L G C C+ G C+RC P F+ +PL
Sbjct: 1910 -----CVSCPCPLSVPSNNFAEGCVLRGGRTQ---CL-CKPGYAGASCERCAPGFFGNPL 1960
Query: 384 KTISDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYG 443
S +C PC+C +G + S DP G+ G C + G +C+ C P YG
Sbjct: 1961 VLGS---SCQPCDCSGNG--DPNLLFSDCDPLTGACRG---CLRHTTGPRCEICAPGFYG 2012
Query: 444 LSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGLGNHLHGC 503
+A P C CDC P G+ CD +G CLC + VTG C+ C G++G GC
Sbjct: 2013 -NALLPGNCTRCDCTPCGTE---ACDPHSGHCLCKAGVTGRRCDRCQEGHFGFDG-CGGC 2067
Query: 504 SPCDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPAPGYFFAP 547
PC C A + C P++GQC CRP G C E APGY+ P
Sbjct: 2068 RPCACG-PAAEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGLP 2110
Score = 159 bits (403), Expect = 2e-38
Identities = 114/347 (32%), Positives = 137/347 (39%), Gaps = 72/347 (20%)
Query: 767 VACKCHPQGSVGSSCSRLGGQC-QCKPLVVGRCCDRCSTG---SYDLGHHGCHPCHCH-- 820
V C+CH C G C C+ G C+RC G S D C C C
Sbjct: 1862 VPCQCHGHSD---RCLPGSGVCVDCQHNTEGAHCERCQAGFVSSRDDPSAPCVSCPCPLS 1918
Query: 821 -PQGSKDTVCDQVTG--QCPCHGEVSGRRCDRCLAGYFGFP-----SCHPCPC------N 866
P + C G QC C +G C+RC G+FG P SC PC C N
Sbjct: 1919 VPSNNFAEGCVLRGGRTQCLCKPGYAGASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPN 1978
Query: 867 RFAELCDPETGSCFNCGGFTTGRNCERCIDGYYGNPSSGQPCRPCLCPD------DPSSN 920
CDP TG+C C TTG CE C G+YGN C C C DP S
Sbjct: 1979 LLFSDCDPLTGACRGCLRHTTGPRCEICAPGFYGNALLPGNCTRCDCTPCGTEACDPHSG 2038
Query: 921 QYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTD 980
C C G TG +C C G +G G C+PCAC +
Sbjct: 2039 H----------------CLCKAGVTGRRCDRCQEGHFGFDGCGG--CRPCACG---PAAE 2077
Query: 981 PESCSRVTGECLRCLHNTQGANCQLCKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGA 1040
C +G+C C T G C+ C PG++G Q CRRC C PGG
Sbjct: 2078 GSECHPQSGQC-HCRPGTMGPQCRECAPGYWGLP-EQGCRRCQC-----------PGG-- 2122
Query: 1041 CLCDPVTGACPCLPNVTGLACDRCADGYWNLVPGR------GCQSCD 1081
CDP TG C C P ++G CD C+ + VPG C+ CD
Sbjct: 2123 -RCDPHTGRCNCPPGLSGERCDTCSQQHQVPVPGGPVGHSIHCEVCD 2168
Score = 155 bits (393), Expect = 3e-37
Identities = 95/258 (36%), Positives = 120/258 (46%), Gaps = 37/258 (14%)
Query: 295 CVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASGGL 354
C+C + G +C+ C F +R L C C C+ HS RC L
Sbjct: 1831 CLCPASYRGDSCQECAPGF----YRDVKGLFLGRCVPCQCHGHSDRC------------L 1874
Query: 355 SG-GVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYA-CIPCECD---PDGTISGGICV 409
G GVC DCQHNTEG HC+RC+ F + + DP A C+ C C P + G CV
Sbjct: 1875 PGSGVCVDCQHNTEGAHCERCQAGF----VSSRDDPSAPCVSCPCPLSVPSNNFAEG-CV 1929
Query: 410 SHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLG--SLPFLT 467
L QCLCK GA C++C P +G CQPCDC+ G +L F
Sbjct: 1930 ------LRGGRTQCLCKPGYAGASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFSD 1983
Query: 468 CDVDTGQCL-CLSYVTGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYSNVCSPKNGQCE 526
CD TG C CL + TG CE C G++G C+ CDC G + C P +G C
Sbjct: 1984 CDPLTGACRGCLRHTTGPRCEICAPGFYGNALLPGNCTRCDCTPCG--TEACDPHSGHCL 2041
Query: 527 CRPHVTGRSCSEPAPGYF 544
C+ VTGR C G+F
Sbjct: 2042 CKAGVTGRRCDRCQEGHF 2059
Score = 148 bits (373), Expect = 5e-35
Identities = 107/347 (30%), Positives = 136/347 (39%), Gaps = 95/347 (27%)
Query: 264 SCFCNGHASECR--PMQKMRGDVFSPPGMVHGQCVC---QHNTDGPNCERCKDFFQDAPW 318
SC C GHA++C P R S G G VC QH+T G NCERC F +P
Sbjct: 358 SCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPN 417
Query: 319 RPAADLQDNACRSCSCNSH---------SSRCHFD------------------------- 344
P + CR C+C S + RC+
Sbjct: 418 HPLDS--PHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCYPTP 475
Query: 345 ----------------MTTYLASGGLSGGVCED--------CQHNTEGQHCDRCRPLFYR 380
+ ++ G G C C+ N +G HC+ C P FY
Sbjct: 476 SSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCAPGFYG 535
Query: 381 DPLKTISDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPN 440
C PC+C S G+ DP GQC C+ EGA CD+C P
Sbjct: 536 P---------GCQPCQCS-----SPGVADDRCDPD----TGQCRCRVGFEGATCDRCAPG 577
Query: 441 HYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGLGNHL 500
++ PL CQ C C+P G+LP CD + G+CLC G HC+ C GY G N
Sbjct: 578 YFHF----PL-CQLCGCSPAGTLP-EGCD-EAGRCLCQPEFAGPHCDRCRPGYHGFPN-- 628
Query: 501 HGCSPCDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPAPGYFFAP 547
C C CD GA +C G C CRP TG +C E +PG+ P
Sbjct: 629 --CQACTCDPRGALDQLCG-AGGLCRCRPGYTGTACQECSPGFHGFP 672
Score = 143 bits (360), Expect = 2e-33
Identities = 81/217 (37%), Positives = 102/217 (47%), Gaps = 21/217 (9%)
Query: 811 HHGCHPCHCHPQGSKDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFPSCHPCPCNRFAE 870
++G PC CH G+ C+ GQCPCH V GR C RC GY+GFP+C PC C A
Sbjct: 1432 NNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGFPNCRPCDCG--AR 1489
Query: 871 LCDPETGSCFNCGGFTTGRNCERCIDGYYG-NPSSGQPCRPCLCPDDPSSNQYFAHSCYQ 929
LCD TG C C T +C C +G +P G C C C P + +C
Sbjct: 1490 LCDELTGQCI-CPPRTIPPDCLLCQPQTFGCHPLVG--CEECNC-SGPGIQELTDPTCDT 1545
Query: 930 NLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTG 989
+ C C TG +C CS GF+G PR C+PC C+ T P C +TG
Sbjct: 1546 DSGQ----CKCRPNVTGRRCDTCSPGFHGYPR-----CRPCDCHE--AGTAPGVCDPLTG 1594
Query: 990 ECLRCLHNTQGANCQLCKPGHYG--SALNQTCRRCSC 1024
+C C N QG C C G + +A + C RC C
Sbjct: 1595 QCY-CKENVQGPKCDQCSLGTFSLDAANPKGCTRCFC 1630
Score = 133 bits (334), Expect = 2e-30
Identities = 80/228 (35%), Positives = 105/228 (46%), Gaps = 32/228 (14%)
Query: 956 FYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQLCKPGHYGSAL 1015
FY N GA +PC C+ + T P +C G+C C + G +C C G++G
Sbjct: 1430 FYNN----GA--RPCGCHE-VGATGP-TCEPFGGQC-PCHAHVIGRDCSRCATGYWGFP- 1479
Query: 1016 NQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCADGYWNLVPGR 1075
CR C C GA LCD +TG C C P C C + P
Sbjct: 1480 --NCRPCDC--------------GARLCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLV 1523
Query: 1076 GCQSCDCDPRTSQS---SHCDQLTGQCPCKLGYGGKRCSECQENYYGDPPGRCIPCDCNR 1132
GC+ C+C Q CD +GQC C+ G+RC C ++G P RC PCDC+
Sbjct: 1524 GCEECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYP--RCRPCDCHE 1581
Query: 1133 AGTQKPICDPDTGMCRCREGVSGQRCDRCARG-HSQEFPTCLQCHLCF 1179
AGT +CDP TG C C+E V G +CD+C+ G S + C CF
Sbjct: 1582 AGTAPGVCDPLTGQCYCKENVQGPKCDQCSLGTFSLDAANPKGCTRCF 1629
Score = 122 bits (306), Expect = 3e-27
Identities = 75/261 (28%), Positives = 114/261 (43%), Gaps = 56/261 (21%)
Query: 706 VDSLGLIPQINSLENFCSKQDLDEYQLHNCVEIASAMGPQVLPGA----CERLIISMSAK 761
+D + ++P+ + ++ LD+ ++ + +A G + P + C S+S
Sbjct: 1373 LDYVLVVPENVYSFGYLREEPLDKS--YDFISHCAAQGYHISPSSSSLFCRNAAASLSLF 1430
Query: 762 LHDGAVACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCSTGSY--------DLGHH- 812
++GA C CH G+ G +C GGQC C V+GR C RC+TG + D G
Sbjct: 1431 YNNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGFPNCRPCDCGARL 1490
Query: 813 ---------------------------GCHP------CHCHPQGSK---DTVCDQVTGQC 836
GCHP C+C G + D CD +GQC
Sbjct: 1491 CDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSGQC 1550
Query: 837 PCHGEVSGRRCDRCLAGYFGFPSCHPCPCNRFAE---LCDPETGSCFNCGGFTTGRNCER 893
C V+GRRCD C G+ G+P C PC C+ +CDP TG C+ C G C++
Sbjct: 1551 KCRPNVTGRRCDTCSPGFHGYPRCRPCDCHEAGTAPGVCDPLTGQCY-CKENVQGPKCDQ 1609
Query: 894 CIDGYYG-NPSSGQPCRPCLC 913
C G + + ++ + C C C
Sbjct: 1610 CSLGTFSLDAANPKGCTRCFC 1630
Score = 106 bits (265), Expect = 2e-22
Identities = 66/227 (29%), Positives = 91/227 (40%), Gaps = 51/227 (22%)
Query: 326 DNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCED------CQHNTEGQHCDRCRPLFY 379
+N R C C+ G +G CE C + G+ C RC ++
Sbjct: 1432 NNGARPCGCHEV---------------GATGPTCEPFGGQCPCHAHVIGRDCSRCATGYW 1476
Query: 380 RDPLKTISDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKP 439
P C PC+C +C + GQC+C C C+P
Sbjct: 1477 GFP--------NCRPCDC------GARLC--------DELTGQCICPPRTIPPDCLLCQP 1514
Query: 440 NHYGLSATDPLGCQPCDCNPLG--SLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGLG 497
+G +GC+ C+C+ G L TCD D+GQC C VTG C+ C+ G+ G
Sbjct: 1515 QTFGCHPL--VGCEECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYP 1572
Query: 498 NHLHGCSPCDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPAPGYF 544
C PCDC G VC P GQC C+ +V G C + + G F
Sbjct: 1573 R----CRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQCSLGTF 1615
Score = 105 bits (262), Expect = 4e-22
Identities = 66/204 (32%), Positives = 86/204 (42%), Gaps = 24/204 (11%)
Query: 767 VACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHGCHPCHCHPQG--S 824
V C C +GS+ ++C GQC C+P V G CD C G+Y+ + C CHP G
Sbjct: 675 VPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVPGAYNFPY--CEAGSCHPAGLAP 732
Query: 825 KDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGF-PS----CHPCPCNRFAEL-----CDP 874
D + C C V G CDRC G++G PS C C C+ L C P
Sbjct: 733 VDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQP 792
Query: 875 ETGSCFNCGGFTTGRNCERCIDGYYG-NPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWS 933
TG CF C G+ C C DG++G + + CR C C + Q SC
Sbjct: 793 GTGQCF-CKPHVCGQACASCKDGFFGLDQADYFGCRSCRCDIGGALGQ----SCEPRTG- 846
Query: 934 SDVICNCLQGYTGTQCGECSTGFY 957
+C C G C E + Y
Sbjct: 847 ---VCRCRPNTQGPTCSEPARDHY 867
Score = 96.7 bits (239), Expect = 2e-19
Identities = 68/218 (31%), Positives = 92/218 (42%), Gaps = 44/218 (20%)
Query: 293 GQCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASG 352
GQC C + G +C RC + P CR C C + R ++T
Sbjct: 1455 GQCPCHAHVIGRDCSRCATGYWGFP----------NCRPCDCGA---RLCDELT------ 1495
Query: 353 GLSGGVCEDCQHNTEGQHCDRCRP-LFYRDPLKTISDPYACIPCECDPDGTISGGICVSH 411
G C C T C C+P F PL C C C SG
Sbjct: 1496 ----GQCI-CPPRTIPPDCLLCQPQTFGCHPL------VGCEECNC------SGPGIQEL 1538
Query: 412 SDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVD 471
+DP + +GQC C+ NV G +CD C P +G C+PCDC+ G+ P + CD
Sbjct: 1539 TDPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYPR-----CRPCDCHEAGTAPGV-CDPL 1592
Query: 472 TGQCLCLSYVTGAHCEECTVGYWGL-GNHLHGCSPCDC 508
TGQC C V G C++C++G + L + GC+ C C
Sbjct: 1593 TGQCYCKENVQGPKCDQCSLGTFSLDAANPKGCTRCFC 1630
Score = 93.2 bits (230), Expect = 2e-18
Identities = 52/138 (37%), Positives = 63/138 (45%), Gaps = 22/138 (15%)
Query: 765 GAVACKCHPQGS---VGSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHGCHPCHCHP 821
G C C G +C GQC+C+P V GR CD CS G + G+ C PC CH
Sbjct: 1524 GCEECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCDTCSPGFH--GYPRCRPCDCHE 1581
Query: 822 QGSKDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFPSCHPCPCNRFAELCDPETGSCFN 881
G+ VCD +TGQC C V G +CD+C G F + +P C R CF
Sbjct: 1582 AGTAPGVCDPLTGQCYCKENVQGPKCDQCSLGTFSLDAANPKGCTR-----------CF- 1629
Query: 882 CGGFTTGRNCERCIDGYY 899
C G T ERC Y
Sbjct: 1630 CFGAT-----ERCRSSSY 1642
Score = 84.7 bits (208), Expect = 7e-16
Identities = 55/176 (31%), Positives = 73/176 (41%), Gaps = 26/176 (14%)
Query: 377 LFYRDPLKTISDPY--ACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKC 434
LF R+ ++S Y PC C G + P GQC C +V G C
Sbjct: 1418 LFCRNAAASLSLFYNNGARPCGCHEVGA---------TGPTCEPFGGQCPCHAHVIGRDC 1468
Query: 435 DQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYW 494
+C ++G C+PCDC CD TGQC+C C C +
Sbjct: 1469 SRCATGYWGFP-----NCRPCDCGAR------LCDELTGQCICPPRTIPPDCLLCQPQTF 1517
Query: 495 GLGNHLHGCSPCDCDIGGAYS---NVCSPKNGQCECRPHVTGRSCSEPAPGYFFAP 547
G + L GC C+C G C +GQC+CRP+VTGR C +PG+ P
Sbjct: 1518 GC-HPLVGCEECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYP 1572
Score = 74.3 bits (181), Expect = 1e-12
Identities = 48/167 (28%), Positives = 65/167 (38%), Gaps = 47/167 (28%)
Query: 1054 PNVTGLACDRCADGYWNLVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSEC 1113
P+ + L C R A +L G + C C + C+ GQCPC G+ CS C
Sbjct: 1413 PSSSSLFC-RNAAASLSLFYNNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRC 1471
Query: 1114 QENYYGDP---------------------PGRCIP---------------------CDCN 1131
Y+G P P R IP C+C+
Sbjct: 1472 ATGYWGFPNCRPCDCGARLCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEECNCS 1531
Query: 1132 RAGTQK---PICDPDTGMCRCREGVSGQRCDRCARGHSQEFPTCLQC 1175
G Q+ P CD D+G C+CR V+G+RCD C+ G +P C C
Sbjct: 1532 GPGIQELTDPTCDTDSGQCKCRPNVTGRRCDTCSPGF-HGYPRCRPC 1577
Score = 69.3 bits (168), Expect = 3e-11
Identities = 47/142 (33%), Positives = 59/142 (41%), Gaps = 12/142 (8%)
Query: 415 ALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLG-CQPCDCNPLGSLPFLTCDVDTG 473
AL S CLC + G C +C P Y LG C PC C+ C +G
Sbjct: 1823 ALASNVELCLCPASYRGDSCQECAPGFYRDVKGLFLGRCVPCQCHGHSD----RCLPGSG 1878
Query: 474 QCL-CLSYVTGAHCEECTVGYWGLGNHLHG-CSPCDCDIGGAYSNV---CSPKNG--QCE 526
C+ C GAHCE C G+ + C C C + +N C + G QC
Sbjct: 1879 VCVDCQHNTEGAHCERCQAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQCL 1938
Query: 527 CRPHVTGRSCSEPAPGYFFAPL 548
C+P G SC APG+F PL
Sbjct: 1939 CKPGYAGASCERCAPGFFGNPL 1960
Score = 63.2 bits (152), Expect = 2e-09
Identities = 38/132 (28%), Positives = 53/132 (40%), Gaps = 8/132 (6%)
Query: 735 CVEIASAMGPQVLPGACERLIISMSAKLHDGAVACKCHPQGSVG--SSCSRLGGQCQCKP 792
C+ A GP C+ +S +G C C +G++G + C GQC CKP
Sbjct: 744 CMCRAHVEGPSC--DRCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKP 801
Query: 793 LVVGRCCDRCSTGSYDL---GHHGCHPCHCHPQGSKDTVCDQVTGQCPCHGEVSGRRCDR 849
V G+ C C G + L + GC C C G+ C+ TG C C G C
Sbjct: 802 HVCGQACASCKDGFFGLDQADYFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSE 861
Query: 850 CLAGYFGFPSCH 861
++ P H
Sbjct: 862 PARDHY-LPDLH 872
>gi|110611156 laminin, gamma 3 precursor [Homo sapiens]
Length = 1575
Score = 277 bits (708), Expect = 7e-74
Identities = 146/366 (39%), Positives = 186/366 (50%), Gaps = 43/366 (11%)
Query: 836 CPCHGEVSGRRCDRCLAGYFG-------FPSCHPCPCNRFAELCDPETGSCFNCGGFTTG 888
C C +G+ C+ C GY + SC PC CN+ CDP TG C C T G
Sbjct: 673 CSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT-CDPNTGICV-CSHHTEG 730
Query: 889 RNCERCIDGYYGNPSSGQP--CRPCLCPDDPSSNQYFAHSCYQNLWSSDVIC-NCLQGYT 945
+CERC+ G+YGNP +GQ C+PC CP + C S +V+C +C G
Sbjct: 731 PSCERCLPGFYGNPFAGQADDCQPCPCPGQSA--------CTTIPESREVVCTHCPPGQR 782
Query: 946 GTQCGECSTGFYGNPR-ISG--APCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGAN 1002
G +C C GF+G+P + G PC C C+ N+D +C ++G CLRCLHNT G +
Sbjct: 783 GRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDH 842
Query: 1003 CQLCKPGHYGSALN----QTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTG 1058
C+ C+ G YGSAL C CSCH G + P CDPVTG C CLP+VT
Sbjct: 843 CEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMP-------CDPVTGQCSCLPHVTA 895
Query: 1059 LACDRCADGYWNLVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSECQENYY 1118
C RC G+++L PGRGC+SC C P SQ C TGQC C+ G G+ C CQ ++
Sbjct: 896 RDCSRCYPGFFDLQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFF 955
Query: 1119 GDPPGRCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDRCARGHSQEFPT-----CL 1173
G C C C+ G C + G C CR G G +CDRC H F T C
Sbjct: 956 GFSIKGCRACRCSPLGAASAQCH-ENGTCVCRPGFEGYKCDRC---HDNFFLTADGTHCQ 1011
Query: 1174 QCHLCF 1179
QC C+
Sbjct: 1012 QCPSCY 1017
Score = 251 bits (640), Expect = 6e-66
Identities = 171/508 (33%), Positives = 235/508 (46%), Gaps = 68/508 (13%)
Query: 28 CHPTTGDLLVGRNTQLMASSTCGLSRAQKYCILSYLEGE-QKCFICDSRFPYDPYDQPNS 86
C P + GR Q AS TCG S + +C G C CD+ P
Sbjct: 35 CLPVFENAAFGRLAQ--ASHTCG-SPPEDFCPHVGAAGAGAHCQRCDAA-------DPQR 84
Query: 87 HTIENVIVSFEPDREKKWWQSEN---GLDH---VSIRLDLEALFRFSHLILTFKTFRPAA 140
H + + F E WWQS + G+ + V+I L L + +++ L F T RP +
Sbjct: 85 HHNASYLTDFHSQDESTWWQSPSMAFGVQYPTSVNITLRLGKAYEITYVRLKFHTSRPES 144
Query: 141 MLVERSTDYGHNWKVFKYFAKDCATSFPNITSGQAQGVGD----IVCDSKYSDIEPSTGG 196
+ + + W+ +++++ C ++ GQ G+ C S++SDI P +GG
Sbjct: 145 FAIYKRSRADGPWEPYQFYSASCQKTYGR-PEGQYLRPGEDERVAFCTSEFSDISPLSGG 203
Query: 197 EVVLKVLDPSFEIEN-PYSPYIQDLVTLTNLRINFTKLHTLGDALLGRRQNDSLDKYYYA 255
V L+ N SP +Q+ VT T L I+ +L+T GD + + L YYYA
Sbjct: 204 NVAFSTLEGRPSAYNFEESPGLQEWVTSTELLISLDRLNTFGDDIF--KDPKVLQSYYYA 261
Query: 256 LYEMIVRGSCFCNGHASECRPMQKMRGDVFSPPGMVHGQ--CVCQHNTDGPNCERCKDFF 313
+ + V G C CNGHASEC P V GQ C CQHNT G +CERC FF
Sbjct: 262 VSDFSVGGRCKCNGHASECGPD-------------VAGQLACRCQHNTTGTDCERCLPFF 308
Query: 314 QDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDR 373
QD PW + C C+C+ S C FD + ++G GG C C+ +T G HC+R
Sbjct: 309 QDRPWARGTAEAAHECLPCNCSGRSEECTFDRELFRSTG--HGGRCHHCRDHTAGPHCER 366
Query: 374 CRPLFYR-DPLKTISDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGA 432
C+ FY DP C PC+C +G + + D G C CK V G
Sbjct: 367 CQENFYHWDP------RMPCQPCDCQS----AGSLHLQCDD------TGTCACKPTVTGW 410
Query: 433 KCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVG 492
KCD+C P + LS GC+PC CNP GSL TCD +G+C C V G C+ C G
Sbjct: 411 KCDRCLPGFHSLSEG---GCRPCTCNPAGSLD--TCDPRSGRCPCKENVEGNLCDRCRPG 465
Query: 493 YWGLGNH-LHGCSPCDCDIGGAYSNVCS 519
+ L H GCS C C +S VC+
Sbjct: 466 TFNLQPHNPAGCSSCFC---YGHSKVCA 490
Score = 206 bits (524), Expect = 2e-52
Identities = 122/363 (33%), Positives = 164/363 (45%), Gaps = 44/363 (12%)
Query: 788 CQCKPLVVGRCCDRCSTG-SYDLGHHG----CHPCHCHPQGSKDTVCDQVTGQCPCHGEV 842
C C G+ C+ C+ G ++ G C PC C+ G+ CD TG C C
Sbjct: 673 CSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT----CDPNTGICVCSHHT 728
Query: 843 SGRRCDRCLAGYFGFP------SCHPCPC-NRFAELCDPETGS--CFNCGGFTTGRNCER 893
G C+RCL G++G P C PCPC + A PE+ C +C GR CE
Sbjct: 729 EGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTHCPPGQRGRRCEV 788
Query: 894 CIDGYYGNP----SSGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQC 949
C DG++G+P QPC C C + N +C S CL TG C
Sbjct: 789 CDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNA--VGNCDP---LSGHCLRCLHNTTGDHC 843
Query: 950 GECSTGFYGN---PRISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQLC 1006
C GFYG+ PR C PC+C+ V++ C VTG+C CL + +C C
Sbjct: 844 EHCQEGFYGSALAPR-PADKCMPCSCHPQGSVSEQMPCDPVTGQC-SCLPHVTARDCSRC 901
Query: 1007 KPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCAD 1066
PG + + CR C CH P G C P TG C C P VTG ACDRC
Sbjct: 902 YPGFFDLQPGRGCRSCKCH---------PLGSQEDQCHPKTGQCTCRPGVTGQACDRCQL 952
Query: 1067 GYWNLVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSECQENYYGDPPG-RC 1125
G++ +GC++C C P + S+ C + G C C+ G+ G +C C +N++ G C
Sbjct: 953 GFFGF-SIKGCRACRCSPLGAASAQCHE-NGTCVCRPGFEGYKCDRCHDNFFLTADGTHC 1010
Query: 1126 IPC 1128
C
Sbjct: 1011 QQC 1013
Score = 160 bits (406), Expect = 8e-39
Identities = 101/285 (35%), Positives = 130/285 (45%), Gaps = 41/285 (14%)
Query: 265 CFCNGHASECRPMQKMRGDVFSPPGMVHGQCVCQHNTDGPNCERCKDFFQDAPWRPAADL 324
C CN H + C P G CVC H+T+GP+CERC F P+ AD
Sbjct: 707 CTCNQHGT-CDPNT--------------GICVCSHHTEGPSCERCLPGFYGNPFAGQAD- 750
Query: 325 QDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLK 384
C+ C C S+ TT S + VC C G+ C+ C F+ DPL
Sbjct: 751 ---DCQPCPCPGQSA-----CTTIPESREV---VCTHCPPGQRGRRCEVCDDGFFGDPLG 799
Query: 385 TISDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCL-CKENVEGAKCDQCKPNHYG 443
P C C+C G + V + DP ++G CL C N G C+ C+ YG
Sbjct: 800 LFGHPQPCHQCQCS--GNVDPN-AVGNCDP----LSGHCLRCLHNTTGDHCEHCQEGFYG 852
Query: 444 LSATDPLG---CQPCDCNPLGSLPF-LTCDVDTGQCLCLSYVTGAHCEECTVGYWGLGNH 499
SA P C PC C+P GS+ + CD TGQC CL +VT C C G++ L
Sbjct: 853 -SALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPG 911
Query: 500 LHGCSPCDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPAPGYF 544
GC C C G+ + C PK GQC CRP VTG++C G+F
Sbjct: 912 -RGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFF 955
Score = 154 bits (390), Expect = 6e-37
Identities = 95/289 (32%), Positives = 123/289 (42%), Gaps = 68/289 (23%)
Query: 937 ICNCLQGYTGTQCGECSTGFYGNPRISG--APCQPCACNNNIDVTDPESCSRVTGECLRC 994
IC+C GYTG C C+ G+ G A C PC CN + +C TG C+ C
Sbjct: 672 ICSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQH------GTCDPNTGICV-C 724
Query: 995 LHNTQGANCQLCKPGHYGSAL---NQTCRRCSC----------HASGVSPMECPPG--GG 1039
H+T+G +C+ C PG YG+ C+ C C + V CPPG G
Sbjct: 725 SHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTHCPPGQRGR 784
Query: 1040 AC------------------------------------LCDPVTGAC-PCLPNVTGLACD 1062
C CDP++G C CL N TG C+
Sbjct: 785 RCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCE 844
Query: 1063 RCADGYWNLV----PGRGCQSCDCDPRTSQSSH--CDQLTGQCPCKLGYGGKRCSECQEN 1116
C +G++ P C C C P+ S S CD +TGQC C + CS C
Sbjct: 845 HCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPG 904
Query: 1117 YYGDPPGR-CIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDRCARG 1164
++ PGR C C C+ G+Q+ C P TG C CR GV+GQ CDRC G
Sbjct: 905 FFDLQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLG 953
Score = 153 bits (386), Expect = 2e-36
Identities = 102/345 (29%), Positives = 134/345 (38%), Gaps = 67/345 (19%)
Query: 767 VACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHG----CHPCHCHPQ 822
V C C+ G+ C G C C G C+RC G Y G C PC C Q
Sbjct: 705 VPCTCNQHGT----CDPNTGICVCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQ 760
Query: 823 GSKDTVCDQVTGQCP-CHGEVSGRRCDRCLAGYFGFP--------SCHPCPCNRFAE--- 870
+ T+ + C C GRRC+ C G+FG P CH C C+ +
Sbjct: 761 SACTTIPESREVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNA 820
Query: 871 --LCDPETGSCFNCGGFTTGRNCERCIDGYYGN---PSSGQPCRPCLC----------PD 915
CDP +G C C TTG +CE C +G+YG+ P C PC C P
Sbjct: 821 VGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPC 880
Query: 916 DPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCACNNN 975
DP + Q C+CL T C C GF+ G C+ C C+
Sbjct: 881 DPVTGQ----------------CSCLPHVTARDCSRCYPGFFDLQ--PGRGCRSCKCHPL 922
Query: 976 IDVTDPESCSRVTGECLRCLHNTQGANCQLCKPGHYGSALNQTCRRCSCHASGVSPMECP 1035
+ + C TG+C C G C C+ G +G ++ + CR C C G + +C
Sbjct: 923 --GSQEDQCHPKTGQC-TCRPGVTGQACDRCQLGFFGFSI-KGCRACRCSPLGAASAQCH 978
Query: 1036 PGGGACLCDPVTGACPCLPNVTGLACDRCADGYWNLVPGRGCQSC 1080
G C C P G CDRC D ++ G CQ C
Sbjct: 979 E----------NGTCVCRPGFEGYKCDRCHDNFFLTADGTHCQQC 1013
Score = 133 bits (335), Expect = 1e-30
Identities = 79/219 (36%), Positives = 103/219 (47%), Gaps = 28/219 (12%)
Query: 332 CSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLK--TISDP 389
C CN H+S C D+ LA C CQHNT G C+RC P F P T
Sbjct: 271 CKCNGHASECGPDVAGQLA--------CR-CQHNTTGTDCERCLPFFQDRPWARGTAEAA 321
Query: 390 YACIPCECD---PDGTISGGICVSHSDPALGSVAGQCL-CKENVEGAKCDQCKPNHYGLS 445
+ C+PC C + T + S G+C C+++ G C++C+ N Y
Sbjct: 322 HECLPCNCSGRSEECTFDRELFRSTGH------GGRCHHCRDHTAGPHCERCQENFYHWD 375
Query: 446 ATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGLGNHLHGCSP 505
P CQPCDC GSL L CD DTG C C VTG C+ C G+ L GC P
Sbjct: 376 PRMP--CQPCDCQSAGSL-HLQCD-DTGTCACKPTVTGWKCDRCLPGFHSLSEG--GCRP 429
Query: 506 CDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPAPGYF 544
C C+ G+ + C P++G+C C+ +V G C PG F
Sbjct: 430 CTCNPAGSL-DTCDPRSGRCPCKENVEGNLCDRCRPGTF 467
Score = 122 bits (305), Expect = 4e-27
Identities = 64/155 (41%), Positives = 79/155 (50%), Gaps = 9/155 (5%)
Query: 764 DGAVACKCHPQGSVGSS--CSRLGGQCQCKPLVVGRCCDRCSTGSYDL-GHHGCHPCHCH 820
D + C CHPQGSV C + GQC C P V R C RC G +DL GC C CH
Sbjct: 861 DKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCH 920
Query: 821 PQGSKDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGF--PSCHPCPCNRF--AELCDPET 876
P GS++ C TGQC C V+G+ CDRC G+FGF C C C+ A E
Sbjct: 921 PLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIKGCRACRCSPLGAASAQCHEN 980
Query: 877 GSCFNCGGFTTGRNCERCIDGYYGNPSSGQPCRPC 911
G+C GF G C+RC D ++ + G C+ C
Sbjct: 981 GTCVCRPGF-EGYKCDRCHDNFF-LTADGTHCQQC 1013
Score = 114 bits (286), Expect = 6e-25
Identities = 67/210 (31%), Positives = 88/210 (41%), Gaps = 24/210 (11%)
Query: 933 SSDVICNCLQGYTGTQCGECSTGFYGNPRISGAP-----CQPCACNNNID-VTDPESCSR 986
+ + C C TGT C C F P G C PC C+ + T R
Sbjct: 285 AGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCSGRSEECTFDRELFR 344
Query: 987 VTGECLRCLH---NTQGANCQLCKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLC 1043
TG RC H +T G +C+ C+ Y C+ C C ++G ++C
Sbjct: 345 STGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMPCQPCDCQSAGSLHLQCDD------- 397
Query: 1044 DPVTGACPCLPNVTGLACDRCADGYWNLVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKL 1103
TG C C P VTG CDRC G+ +L G GC+ C C+P S + CD +G+CPCK
Sbjct: 398 ---TGTCACKPTVTGWKCDRCLPGFHSLSEG-GCRPCTCNPAGSLDT-CDPRSGRCPCKE 452
Query: 1104 GYGGKRCSECQE---NYYGDPPGRCIPCDC 1130
G C C+ N P C C C
Sbjct: 453 NVEGNLCDRCRPGTFNLQPHNPAGCSSCFC 482
Score = 114 bits (285), Expect = 8e-25
Identities = 66/201 (32%), Positives = 87/201 (43%), Gaps = 12/201 (5%)
Query: 970 CACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQLCKPGH----YGSALNQTCRRC-SC 1024
C CN + P+ ++ RC HNT G +C+ C P + + C C
Sbjct: 271 CKCNGHASECGPDVAGQLA---CRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPC 327
Query: 1025 HASGVSPMECPPGGGACLCDPVTGACP-CLPNVTGLACDRCADGYWNLVPGRGCQSCDCD 1083
+ SG S EC G C C + G C+RC + +++ P CQ CDC
Sbjct: 328 NCSGRSE-ECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMPCQPCDCQ 386
Query: 1084 PRTSQSSHCDQLTGQCPCKLGYGGKRCSECQENYYGDPPGRCIPCDCNRAGTQKPICDPD 1143
S CD TG C CK G +C C ++ G C PC CN AG+ CDP
Sbjct: 387 SAGSLHLQCDD-TGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGS-LDTCDPR 444
Query: 1144 TGMCRCREGVSGQRCDRCARG 1164
+G C C+E V G CDRC G
Sbjct: 445 SGRCPCKENVEGNLCDRCRPG 465
Score = 112 bits (279), Expect = 4e-24
Identities = 73/235 (31%), Positives = 94/235 (40%), Gaps = 38/235 (16%)
Query: 863 CPCNRFAELCDPETGS--CFNCGGFTTGRNCERCIDGYYGNP------SSGQPCRPCLCP 914
C CN A C P+ C TTG +CERC+ + P + C PC C
Sbjct: 271 CKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNC- 329
Query: 915 DDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYG-NPRISGAPCQPCACN 973
S F +++ +C G C C FY +PR+ PCQPC C
Sbjct: 330 SGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRM---PCQPCDCQ 386
Query: 974 N----NIDVTDPESCSRVTGECLRCLHNTQGANCQLCKPGHYGSALNQTCRRCSCHASGV 1029
+ ++ D +C+ C G C C PG + S CR C+C+
Sbjct: 387 SAGSLHLQCDDTGTCA--------CKPTVTGWKCDRCLPGFH-SLSEGGCRPCTCN---- 433
Query: 1030 SPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCADGYWNLVPGR--GCQSCDC 1082
P G CDP +G CPC NV G CDRC G +NL P GC SC C
Sbjct: 434 ------PAGSLDTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFC 482
Score = 100 bits (249), Expect = 1e-20
Identities = 75/247 (30%), Positives = 91/247 (36%), Gaps = 79/247 (31%)
Query: 362 CQHNTEGQHCDRCRPLFYRDPLKTISDPYA-CIPCECDPDGTISGGICVSHSDPALGSVA 420
C GQ C+ C P + R+ + PYA C+PC C+ GT DP
Sbjct: 675 CPTGYTGQFCESCAPGYKREMPQ--GGPYASCVPCTCNQHGT---------CDPN----T 719
Query: 421 GQCLCKENVEGAKCDQCKPNHYGLS-ATDPLGCQPCDC---------------------- 457
G C+C + EG C++C P YG A CQPC C
Sbjct: 720 GICVCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTHCPP 779
Query: 458 ----------------NPLGSL----PFLTC--------------DVDTGQCL-CLSYVT 482
+PLG P C D +G CL CL T
Sbjct: 780 GQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTT 839
Query: 483 GAHCEECTVGYWGLG---NHLHGCSPCDCDIGGAYSN--VCSPKNGQCECRPHVTGRSCS 537
G HCE C G++G C PC C G+ S C P GQC C PHVT R CS
Sbjct: 840 GDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCS 899
Query: 538 EPAPGYF 544
PG+F
Sbjct: 900 RCYPGFF 906
Score = 95.1 bits (235), Expect = 5e-19
Identities = 44/98 (44%), Positives = 51/98 (52%), Gaps = 2/98 (2%)
Query: 769 CKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHGCHPCHCHPQGSKDTV 828
C C GS+ C G C CKP V G CDRC G + L GC PC C+P GS DT
Sbjct: 383 CDCQSAGSLHLQCDDTG-TCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLDT- 440
Query: 829 CDQVTGQCPCHGEVSGRRCDRCLAGYFGFPSCHPCPCN 866
CD +G+CPC V G CDRC G F +P C+
Sbjct: 441 CDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCS 478
Score = 92.8 bits (229), Expect = 3e-18
Identities = 69/233 (29%), Positives = 92/233 (39%), Gaps = 46/233 (19%)
Query: 819 CHPQGSKDTVCDQVTGQ--CPCHGEVSGRRCDRCLAGYFGFP----------SCHPCPCN 866
C G V GQ C C +G C+RCL + P C PC C+
Sbjct: 271 CKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCS 330
Query: 867 RFAELC--DPET-------GSCFNCGGFTTGRNCERCIDGYYGNPSSGQPCRPCLCPDDP 917
+E C D E G C +C T G +CERC + +Y + PC+PC C
Sbjct: 331 GRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFY-HWDPRMPCQPCDCQSAG 389
Query: 918 SSNQYFAHSCYQNLWSSDV-ICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCACN--N 974
S + L D C C TG +C C GF+ +S C+PC CN
Sbjct: 390 SLH----------LQCDDTGTCACKPTVTGWKCDRCLPGFHS---LSEGGCRPCTCNPAG 436
Query: 975 NIDVTDPESCSRVTGECLRCLHNTQGANCQLCKPGHYGSALNQT--CRRCSCH 1025
++D DP S G C C N +G C C+PG + + C C C+
Sbjct: 437 SLDTCDPRS-----GRC-PCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFCY 483
Score = 89.0 bits (219), Expect = 4e-17
Identities = 40/103 (38%), Positives = 48/103 (46%), Gaps = 4/103 (3%)
Query: 765 GAVACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHGCHPCHCHPQGS 824
G +CKCHP GS C GQC C+P V G+ CDRC G + GC C C P G+
Sbjct: 913 GCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIKGCRACRCSPLGA 972
Query: 825 KDTVCDQVTGQCPCHGEVSGRRCDRCLAGYF---GFPSCHPCP 864
C + G C C G +CDRC +F C CP
Sbjct: 973 ASAQCHE-NGTCVCRPGFEGYKCDRCHDNFFLTADGTHCQQCP 1014
Score = 79.0 bits (193), Expect = 4e-14
Identities = 62/238 (26%), Positives = 89/238 (37%), Gaps = 62/238 (26%)
Query: 776 SVGSSCSRLGGQCQCKPLVVGRC------------CDRC---------STGSYDLGHHGC 814
SVG C G +C P V G+ C+RC + G+ + H C
Sbjct: 266 SVGGRCKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHE-C 324
Query: 815 HPCHCHPQGSKDTVCDQV------TGQC-PCHGEVSGRRCDRCLAGYFGFP---SCHPCP 864
PC+C + + T ++ G+C C +G C+RC ++ + C PC
Sbjct: 325 LPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMPCQPCD 384
Query: 865 CNRFAEL---CDPETGSCFNCGGFTTGRNCERCIDGYYGNPSSGQPCRPCLCPD------ 915
C L CD +TG+C C TG C+RC+ G++ G CRPC C
Sbjct: 385 CQSAGSLHLQCD-DTGTC-ACKPTVTGWKCDRCLPGFHSLSEGG--CRPCTCNPAGSLDT 440
Query: 916 -DPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCAC 972
DP S + C C + G C C G + + A C C C
Sbjct: 441 CDPRSGR----------------CPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFC 482
Score = 73.6 bits (179), Expect = 2e-12
Identities = 43/137 (31%), Positives = 54/137 (39%), Gaps = 16/137 (11%)
Query: 423 CLCKENVEGAKCDQCKPNHYGLSATDPLG-----CQPCDCNPLGSLPFLTCDVDTGQCLC 477
C C G C+ C P G P G C PC CN G TCD +TG C+C
Sbjct: 673 CSCPTGYTGQFCESCAP---GYKREMPQGGPYASCVPCTCNQHG-----TCDPNTGICVC 724
Query: 478 LSYVTGAHCEECTVGYWG--LGNHLHGCSPCDCDIGGAYSNVCSPKNGQC-ECRPHVTGR 534
+ G CE C G++G C PC C A + + + C C P GR
Sbjct: 725 SHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTHCPPGQRGR 784
Query: 535 SCSEPAPGYFFAPLNFY 551
C G+F PL +
Sbjct: 785 RCEVCDDGFFGDPLGLF 801
Score = 58.9 bits (141), Expect = 4e-08
Identities = 29/83 (34%), Positives = 40/83 (48%), Gaps = 4/83 (4%)
Query: 741 AMGPQVLPGACERLIISMSAKLHDGAVACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCD 800
A P V C+R + + G C C+P GS+ +C G+C CK V G CD
Sbjct: 402 ACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSL-DTCDPRSGRCPCKENVEGNLCD 460
Query: 801 RCSTGSYDLGHH---GCHPCHCH 820
RC G+++L H GC C C+
Sbjct: 461 RCRPGTFNLQPHNPAGCSSCFCY 483
Score = 43.5 bits (101), Expect = 0.002
Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 2/76 (2%)
Query: 744 PQVLPGACERLIISMSAKLHDGAVACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCS 803
P V AC+R + G AC+C P G+ + C G C C+P G CDRC
Sbjct: 940 PGVTGQACDRCQLGFFGFSIKGCRACRCSPLGAASAQCHE-NGTCVCRPGFEGYKCDRCH 998
Query: 804 TGSYDLGHHGCHPCHC 819
++ L G H C
Sbjct: 999 -DNFFLTADGTHCQQC 1013
Score = 32.7 bits (73), Expect = 3.2
Identities = 13/36 (36%), Positives = 20/36 (55%), Gaps = 6/36 (16%)
Query: 1146 MCRCREGVSGQRCDRCARGHSQEFP------TCLQC 1175
+C C G +GQ C+ CA G+ +E P +C+ C
Sbjct: 672 ICSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPC 707
Score = 31.6 bits (70), Expect = 7.1
Identities = 19/68 (27%), Positives = 24/68 (35%), Gaps = 4/68 (5%)
Query: 292 HGQCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLAS 351
+G CVC+ +G C+RC D F + A C SC L
Sbjct: 980 NGTCVCRPGFEGYKCDRCHDNF----FLTADGTHCQQCPSCYALVKEEAAKLKARLTLTE 1035
Query: 352 GGLSGGVC 359
G L G C
Sbjct: 1036 GWLQGSDC 1043
>gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens]
Length = 3333
Score = 270 bits (691), Expect = 7e-72
Identities = 175/571 (30%), Positives = 269/571 (47%), Gaps = 93/571 (16%)
Query: 29 HPTTGDLLVGRNTQLMASSTCG-------LSRAQKYCIL----------SYLEGEQKCFI 71
HPT +L ++ A++TCG + + YC L ++G Q C
Sbjct: 48 HPTYFNL--AEAARIWATATCGERGPGEGRPQPELYCKLVGGPTAPGSGHTIQG-QFCDY 104
Query: 72 CDSRFPYDPYDQPNSHTIENVIVSFEPDREKKWWQSE-----NGLDHVSIRLDLEALFRF 126
C+S D +H + N I D ++WWQS + V++ LDL LF
Sbjct: 105 CNSE------DPRKAHPVTNAI-----DGSERWWQSPPLSSGTQYNRVNLTLDLGQLFHV 153
Query: 127 SHLILTFKTF-RPAAMLVERSTDYGHNWKVFKYFAK---DCATSFPNITSGQAQGVGDIV 182
+++++ F RP ++ERS D+G + ++YFA DC F + D++
Sbjct: 154 AYILIKFANSPRPDLWVLERSVDFGSTYSPWQYFAHSKVDCLKEFGREANMAVTRDDDVL 213
Query: 183 CDSKYSDIEPSTGGEVVLKVLDPSFEIEN-PYSPYIQDLVTLTNLRINFTKLHTLGDALL 241
C ++YS I P GEVV+ +++ +N +S +++ TN+R+ F + +TL L+
Sbjct: 214 CVTEYSRIVPLENGEVVVSLINGRPGAKNFTFSHTLREFTKATNIRLRFLRTNTLLGHLI 273
Query: 242 GRRQNDSL--DKYYYALYEMIVRGSCFCNGHASECRPMQKMRGDVFSPPGMVHGQCVCQH 299
+ Q D +YYY++ ++ + G C CNGHA C ++ +P + +C CQH
Sbjct: 274 SKAQRDPTVTRRYYYSIKDISIGGQCVCNGHAEVC--------NINNPEKLF--RCECQH 323
Query: 300 NTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASGGLS---- 355
+T G C+RC + WRPAA Q + C +C+C+ H+S C++D L+
Sbjct: 324 HTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQASLNTQGI 383
Query: 356 ---GGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSHS 412
GGVC +CQHNT G +C++C +YR + P CIPC CDP+ H+
Sbjct: 384 YAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPE----------HA 433
Query: 413 DPALGSVAGQCLCKENVEGAKCDQCKPNHYGL--------------SATDPLG--CQPCD 456
D +G+C CK N G C++C +Y S+ DP+ + CD
Sbjct: 434 D-GCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCD 492
Query: 457 CNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYSN 516
CN G LP + CD G+CLC V G C+ C G++ C C C G+Y
Sbjct: 493 CNLEGVLPEI-CDAH-GRCLCRPGVEGPRCDTCRSGFYSFPI----CQACWCSALGSYQM 546
Query: 517 VCSPKNGQCECRPHVTGRSCSEPAPGYFFAP 547
CS GQCECRP VTG+ C G + P
Sbjct: 547 PCSSVTGQCECRPGVTGQRCDRCLSGAYDFP 577
Score = 170 bits (430), Expect = 1e-41
Identities = 132/446 (29%), Positives = 170/446 (38%), Gaps = 81/446 (18%)
Query: 835 QCPCHGEVSGRRCDRCLAGYFG----------FPSCHPCPCNRFAELC--DPET------ 876
+C C G CDRC GY C C C+ A C DP+
Sbjct: 318 RCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQAS 377
Query: 877 ----------GSCFNCGGFTTGRNCERCIDGYY---GNP-SSGQPCRPCLCPDDPSSNQY 922
G C NC T G NCE+C GYY G P + C PC C DP
Sbjct: 378 LNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSC--DPEH--- 432
Query: 923 FAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCA----------- 971
A C Q C+C + G C +C+ G+Y P P P +
Sbjct: 433 -ADGCEQGSGR----CHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGD 487
Query: 972 ---CNNNIDVTDPESCSRVTGECLRCLHNTQGANCQLCKPGHYGSALNQTCRRCSCHASG 1028
C+ N++ PE C G CL C +G C C+ G Y + C+ C C A G
Sbjct: 488 IKGCDCNLEGVLPEICD-AHGRCL-CRPGVEGPRCDTCRSGFYSFPI---CQACWCSALG 542
Query: 1029 VSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCADGYWNLVPGRGCQSCDCDPRTSQ 1088
M C VTG C C P VTG CDRC G ++ +G S CDP +
Sbjct: 543 SYQMPC---------SSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSA-CDPAGTI 592
Query: 1089 SSHCDQLTGQCPCKLGYGGKRCSECQENYYG---DPPGRCIPCDCNRAGTQKPI--CDPD 1143
+S+ G C CKL G CS C+ Y+ + P C C C++AGT C
Sbjct: 593 NSNL----GYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQG 648
Query: 1144 TGMCRCREGVSGQRCDRCARGH-SQEFPTCLQCHLCFDQWDHTISSLSKAVQGLMRLAAN 1202
G C C+ V G CD C G+ + E C C +SS+ G+ + +
Sbjct: 649 DGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREH 708
Query: 1203 MEDKRETLPVCEADFKDLRGNVSEIE 1228
+ K P F DL EIE
Sbjct: 709 VVGKVCQRPENNYYFPDLHHMKYEIE 734
Score = 166 bits (421), Expect = 1e-40
Identities = 126/423 (29%), Positives = 165/423 (39%), Gaps = 73/423 (17%)
Query: 787 QCQCKPLVVGRCCDRCSTG---------SYDLGHHGCHPCHCHPQGSK-----DTVCDQV 832
+C+C+ G CDRC TG +++ H C C+CH S D Q
Sbjct: 318 RCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHE-CEACNCHGHASNCYYDPDVERQQA 376
Query: 833 T----------GQC-PCHGEVSGRRCDRCLAGY---FGFP-----SCHPCPCN-RFAELC 872
+ G C C +G C++C GY +G P C PC C+ A+ C
Sbjct: 377 SLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHADGC 436
Query: 873 DPETGSCFNCGGFTTGRNCERCIDGYYGNPSSGQ-PCRPCLCP--DDPSSNQYFAHSC-- 927
+ +G C +C G NCE+C GYY P + P P P +DP + C
Sbjct: 437 EQGSGRC-HCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNL 495
Query: 928 ---YQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTDPESC 984
+ + C C G G +C C +GFY P CQ C C+ P C
Sbjct: 496 EGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFP-----ICQACWCSALGSYQMP--C 548
Query: 985 SRVTGECLRCLHNTQGANCQLCKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCD 1044
S VTG+C C G C C G Y H G S C P G +
Sbjct: 549 SSVTGQC-ECRPGVTGQRCDRCLSGAYDFP----------HCQG-SSSACDPAG---TIN 593
Query: 1045 PVTGACPCLPNVTGLACDRCADGYWNLVPGR--GCQSCDCDP--RTSQSSHCDQLTGQCP 1100
G C C +V G C RC YWNL GC C C S + C Q G C
Sbjct: 594 SNLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCH 653
Query: 1101 CKLGYGGKRCSECQENYYGDPPGR---CIPCDCNRAGTQKPICDPDTGMCRCREGVSGQR 1157
CK GG C C++ Y+ C C C+ G +C +G+C+CRE V G+
Sbjct: 654 CKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKV 713
Query: 1158 CDR 1160
C R
Sbjct: 714 CQR 716
Score = 163 bits (413), Expect = 1e-39
Identities = 92/279 (32%), Positives = 129/279 (46%), Gaps = 50/279 (17%)
Query: 292 HGQCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLAS 351
HG+C+C+ +GP C+ C+ F P C++C C++ S Y
Sbjct: 506 HGRCLCRPGVEGPRCDTCRSGFYSFP----------ICQACWCSALGS--------YQMP 547
Query: 352 GGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCE-----CDPDGTISGG 406
G CE C+ GQ CDRC +S Y C+ CDP GTI+
Sbjct: 548 CSSVTGQCE-CRPGVTGQRCDRC-----------LSGAYDFPHCQGSSSACDPAGTINSN 595
Query: 407 ICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFL 466
+ G C CK +VEG C +CK ++ L +P GC C C+ G++
Sbjct: 596 L-------------GYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGT 642
Query: 467 -TCDVDTGQCLCLSYVTGAHCEECTVGYWGLG-NHLHGCSPCDCDIGGAYSNVCSPKNGQ 524
C G C C S+V G C+ C GY+ L ++ GC C CDIGGA S++CS +G
Sbjct: 643 GECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGV 702
Query: 525 CECRPHVTGRSCSEPAPGYFFAPLNFYLYEAEEATTLQG 563
C+CR HV G+ C P Y+F L+ YE E+ +T G
Sbjct: 703 CQCREHVVGKVCQRPENNYYFPDLHHMKYEIEDGSTPNG 741
Score = 148 bits (374), Expect = 4e-35
Identities = 110/373 (29%), Positives = 144/373 (38%), Gaps = 76/373 (20%)
Query: 785 GGQC-QCKPLVVGRCCDRCSTGSYDL------GHHGCHPCHCHPQGSKDTVCDQVTGQCP 837
GG C C+ G C++C+ G Y GC PC C P+ + C+Q +G+C
Sbjct: 387 GGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHADG--CEQGSGRCH 444
Query: 838 CHGEVSGRRCDRCLAGYFGFPSC---------------------HPCPCNR---FAELCD 873
C G C++C GY+ FP C C CN E+CD
Sbjct: 445 CKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICD 504
Query: 874 PETGSCFNCGGFTTGRNCERCIDGYYGNPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWS 933
G C C G C+ C G+Y P C+ C C A YQ S
Sbjct: 505 AH-GRCL-CRPGVEGPRCDTCRSGFYSFPI----CQACWCS---------ALGSYQMPCS 549
Query: 934 SDV-ICNCLQGYTGTQCGECSTGFYGNPRISGAP--CQPCAC-NNNIDVTDPESCSRVTG 989
S C C G TG +C C +G Y P G+ C P N+N+ G
Sbjct: 550 SVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAGTINSNL------------G 597
Query: 990 ECLRCLHNTQGANCQLCKPGHYGSALNQT--CRRCSCHASGVSPMECPPGGGACLCDPVT 1047
C +C + +G C CK ++ C C CH +G G C
Sbjct: 598 YC-QCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTV-------SGTGECRQGD 649
Query: 1048 GACPCLPNVTGLACDRCADGYWNLVPGR--GCQSCDCDPRTSQSSHCDQLTGQCPCKLGY 1105
G C C +V G +CD C DGY+ L GCQ C CD + SS C +G C C+
Sbjct: 650 GDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHV 709
Query: 1106 GGKRCSECQENYY 1118
GK C + NYY
Sbjct: 710 VGKVCQRPENNYY 722
Score = 147 bits (372), Expect = 7e-35
Identities = 123/428 (28%), Positives = 177/428 (41%), Gaps = 61/428 (14%)
Query: 567 LGSETFGQSPAVHVVLGEPVPGNPVTWTGPGFARVLPGAGLRFAVNNI------PFPVDF 620
L ET + + V+ G P P P + P VLPG L+ N + P +
Sbjct: 1070 LAHETPPTALILDVLSGRPFPHLPQQ-SSPS-VDVLPGVTLKAPQNQVTLRGRVPHLGRY 1127
Query: 621 TIAIHYETQSAADWTVQIVVN---PPGGSEHC--IPKTLQSKPQSFALPAATRIMLLPTP 675
IH+ + + Q+ V+ P GS H P L + Q A +
Sbjct: 1128 VFVIHFYQAAHPTFPAQVSVDGGWPRAGSFHASFCPHVLGCRDQVIAEGQIEFDIS---- 1183
Query: 676 ICLEPDVQYSIDVYFSQPLQGESHAHSHVLVDSLGLIPQINSLENFCSKQDLDEYQ--LH 733
EP+V ++ V +G+S VLV +P N K+ +D+ +
Sbjct: 1184 ---EPEVAATVKVP-----EGKSLVLVRVLV-----VPAENYDYQILHKKSMDKSLEFIT 1230
Query: 734 NCVEIASAMGPQVLPGACERLIISMSAKLHDGAVACKCHPQGSVGSSCSRLGGQCQCKPL 793
NC + + + PQ C+ S+ A H GA+ C+CHP G+ G CS GGQC C+P
Sbjct: 1231 NCGKNSFYLDPQTASRFCKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPN 1290
Query: 794 VVGRCCDRCSTGSYDLGHHGCHPCHCHPQGSKDTVCDQVTGQCPCHGEVSGRRCDRCLAG 853
V+GR C RC+TG Y G C PC C + +C+++TGQC C +C+ C
Sbjct: 1291 VIGRQCTRCATGHY--GFPRCKPCSCGRR-----LCEEMTGQCRCPPRTVRPQCEVCETH 1343
Query: 854 YFGF---PSCHPCPCNRFAEL------CDPETGSCFNCGGFTTGRNCERCIDGYYGNPSS 904
F F C C C+R + CD ++G C C TGR C+RC G+Y P
Sbjct: 1344 SFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQC-RCKPRITGRQCDRCASGFYRFPE- 1401
Query: 905 GQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISG 964
C PC C D + C + C C + GT+C C G + +
Sbjct: 1402 ---CVPCNCNRDGTE----PGVCDPGTGA----CLCKENVEGTECNVCREGSFHLDPANL 1450
Query: 965 APCQPCAC 972
C C C
Sbjct: 1451 KGCTSCFC 1458
Score = 144 bits (364), Expect = 6e-34
Identities = 83/236 (35%), Positives = 101/236 (42%), Gaps = 21/236 (8%)
Query: 792 PLVVGRCCDRCSTGSYDLGHHGCHPCHCHPQGSKDTVCDQVTGQCPCHGEVSGRRCDRCL 851
P R C + H G PC CHP G+ C GQCPC V GR+C RC
Sbjct: 1241 PQTASRFCKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCA 1300
Query: 852 AGYFGFPSCHPCPCNRFAELCDPETGSCFNCGGFTTGRNCERC-IDGYYGNPSSGQPCRP 910
G++GFP C PC C R LC+ TG C C T CE C + +P +G C
Sbjct: 1301 TGHYGFPRCKPCSCGR--RLCEEMTGQC-RCPPRTVRPQCEVCETHSFSFHPMAG--CEG 1355
Query: 911 CLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPC 970
C C S + + C C TG QC C++GFY P C PC
Sbjct: 1356 CNC-----SRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFPE-----CVPC 1405
Query: 971 ACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQLCKPG--HYGSALNQTCRRCSC 1024
CN D T+P C TG CL C N +G C +C+ G H A + C C C
Sbjct: 1406 NCNR--DGTEPGVCDPGTGACL-CKENVEGTECNVCREGSFHLDPANLKGCTSCFC 1458
Score = 141 bits (356), Expect = 5e-33
Identities = 84/252 (33%), Positives = 113/252 (44%), Gaps = 43/252 (17%)
Query: 947 TQCGECSTGFYGNPRISGAPCQ---------------PCACNNNIDVTDPESCSRVTGEC 991
T CG+ S FY +P+ + C+ PC C+ T P CS G+C
Sbjct: 1230 TNCGKNS--FYLDPQTASRFCKNSARSLVAFYHKGALPCECHPT-GATGPH-CSPEGGQC 1285
Query: 992 LRCLHNTQGANCQLCKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACP 1051
C N G C C GHYG C+ CSC G LC+ +TG C
Sbjct: 1286 -PCQPNVIGRQCTRCATGHYGFP---RCKPCSC--------------GRRLCEEMTGQCR 1327
Query: 1052 CLPNVTGLACDRCADGYWNLVPGRGCQSCDCDPRTSQSS---HCDQLTGQCPCKLGYGGK 1108
C P C+ C ++ P GC+ C+C R + + CD+ +GQC CK G+
Sbjct: 1328 CPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGR 1387
Query: 1109 RCSECQENYYGDPPGRCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDRCARGHSQE 1168
+C C +Y P C+PC+CNR GT+ +CDP TG C C+E V G C+ C G
Sbjct: 1388 QCDRCASGFYRFP--ECVPCNCNRDGTEPGVCDPGTGACLCKENVEGTECNVCREGSFHL 1445
Query: 1169 FPTCLQ-CHLCF 1179
P L+ C CF
Sbjct: 1446 DPANLKGCTSCF 1457
Score = 140 bits (354), Expect = 8e-33
Identities = 98/332 (29%), Positives = 130/332 (39%), Gaps = 50/332 (15%)
Query: 863 CPCNRFAELCD---PETGSCFNCGGFTTGRNCERCIDGYYGNPSSGQP--------CRPC 911
C CN AE+C+ PE C T G C+RC GY N +P C C
Sbjct: 299 CVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGY--NQRRWRPAAWEQSHECEAC 356
Query: 912 LCPD-------DPSSNQYFAHSCYQNLWSSDVIC-NCLQGYTGTQCGECSTGFY---GNP 960
C DP + A Q +++ +C NC G C +C+ G+Y G P
Sbjct: 357 NCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVP 416
Query: 961 RISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQLCKPGHYGSALNQTCR 1020
+ C PC+C D + C + +G C C N G NC+ C G+Y C
Sbjct: 417 VDAPDGCIPCSC----DPEHADGCEQGSGRC-HCKPNFHGDNCEKCAIGYYNFPF---CL 468
Query: 1021 RCSCHASGVSPMECPPGGGACLCD-----------PVTGACPCLPNVTGLACDRCADGYW 1069
R E P G CD G C C P V G CD C G++
Sbjct: 469 RIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFY 528
Query: 1070 NLVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSECQENYYGDPPGRCIPCD 1129
+ CQ+C C S C +TGQC C+ G G+RC C Y P +
Sbjct: 529 SFPI---CQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSA 585
Query: 1130 CNRAGTQKPICDPDTGMCRCREGVSGQRCDRC 1161
C+ AGT + + G C+C+ V G C RC
Sbjct: 586 CDPAGT----INSNLGYCQCKLHVEGPTCSRC 613
Score = 137 bits (346), Expect = 7e-32
Identities = 87/332 (26%), Positives = 134/332 (40%), Gaps = 56/332 (16%)
Query: 764 DGAVACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHGCHP------- 816
DG + C C P+ + G C + G+C CKP G C++C+ G Y+ P
Sbjct: 421 DGCIPCSCDPEHADG--CEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTP 478
Query: 817 ------------CHCHPQGSKDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFPSCHPCP 864
C C+ +G +CD G+C C V G RCD C +G++ FP C C
Sbjct: 479 SSEDPVAGDIKGCDCNLEGVLPEICD-AHGRCLCRPGVEGPRCDTCRSGFYSFPICQACW 537
Query: 865 CNRFAEL---CDPETGSCFNCGGFTTGRNCERCIDGYYGNPSSGQPCRPCLCPDDPSSNQ 921
C+ C TG C C TG+ C+RC+ G Y P C+ DP+
Sbjct: 538 CSALGSYQMPCSSVTGQC-ECRPGVTGQRCDRCLSGAYDFPH----CQGSSSACDPAG-- 590
Query: 922 YFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTDP 981
+ S+ C C G C C ++ + + + C C C+ V+
Sbjct: 591 --------TINSNLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGT 642
Query: 982 ESCSRVTGECLRCLHNTQGANCQLCKPGHYGSALNQT----CRRCSCHASGVSPMECPPG 1037
C + G+C C + G +C C+ G++ AL ++ C+ C C G
Sbjct: 643 GECRQGDGDC-HCKSHVGGDSCDTCEDGYF--ALEKSNYFGCQGCQCDIGGAL------- 692
Query: 1038 GGACLCDPVTGACPCLPNVTGLACDRCADGYW 1069
+ +C +G C C +V G C R + Y+
Sbjct: 693 --SSMCSGPSGVCQCREHVVGKVCQRPENNYY 722
Score = 135 bits (340), Expect = 4e-31
Identities = 68/163 (41%), Positives = 85/163 (52%), Gaps = 16/163 (9%)
Query: 836 CPCHGEVSGRRCDRCLAGYFGFPS------CHPCPCNRFAELCDPETGSCFNCGGFTTGR 889
C C +G C C GY+ C PC CN + C +G C NC T G
Sbjct: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGE 1713
Query: 890 NCERCIDGYYGNPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQC 949
+CERC +GYYGN G CR C CP S FA C N DV C+C GYTGTQC
Sbjct: 1714 HCERCQEGYYGNAVHGS-CRACPCPHTNS----FATGCVVN--GGDVRCSCKAGYTGTQC 1766
Query: 950 GECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECL 992
C+ G++GNP+ G CQPC+CN+N + SC +TG+C+
Sbjct: 1767 ERCAPGYFGNPQKFGGSCQPCSCNSNGQL---GSCHPLTGDCI 1806
Score = 110 bits (274), Expect = 2e-23
Identities = 59/182 (32%), Positives = 81/182 (44%), Gaps = 16/182 (8%)
Query: 937 ICNCLQGYTGTQCGECSTGFYGNPR-ISGAPCQPCACNNNIDVTDPESCSRVTGECLRCL 995
IC C Y G C CS G+Y + + + C PC CN + + C +G C+ C
Sbjct: 1653 ICACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSN-----QCQDGSGICVNCQ 1707
Query: 996 HNTQGANCQLCKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPN 1055
HNT G +C+ C+ G+YG+A++ +CR C C + C GG C C
Sbjct: 1708 HNTAGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDV-------RCSCKAG 1760
Query: 1056 VTGLACDRCADGYWNLVP--GRGCQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSEC 1113
TG C+RCA GY+ G CQ C C+ Q C LTG C + EC
Sbjct: 1761 YTGTQCERCAPGYFGNPQKFGGSCQPCSCN-SNGQLGSCHPLTGDCINQEPKDSSPAEEC 1819
Query: 1114 QE 1115
+
Sbjct: 1820 DD 1821
Score = 102 bits (253), Expect = 4e-21
Identities = 56/195 (28%), Positives = 84/195 (43%), Gaps = 29/195 (14%)
Query: 295 CVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASGGL 354
C C G +C+ C + +R L C C+CN HS++C
Sbjct: 1654 CACPPAYAGDSCQGCSPGY----YRDHKGLYTGRCVPCNCNGHSNQCQD----------- 1698
Query: 355 SGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSHSDP 414
G+C +CQHNT G+HC+RC+ +Y + + +C C C + + G V+ D
Sbjct: 1699 GSGICVNCQHNTAGEHCERCQEGYYGNAVHG-----SCRACPCPHTNSFATGCVVNGGDV 1753
Query: 415 ALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQ 474
+C CK G +C++C P ++G CQPC CN G L +C TG
Sbjct: 1754 -------RCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLG--SCHPLTGD 1804
Query: 475 CLCLSYVTGAHCEEC 489
C+ + EEC
Sbjct: 1805 CINQEPKDSSPAEEC 1819
Score = 100 bits (249), Expect = 1e-20
Identities = 83/308 (26%), Positives = 123/308 (39%), Gaps = 44/308 (14%)
Query: 990 ECLRCLHNTQGANCQLCKPGHYGSALNQTCRRC-SCHASGVSPMECPPGGGACLCDPVTG 1048
E C G +CQ C PG+Y RC C+ +G S +C G G C+
Sbjct: 1652 EICACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSN-QCQDGSGICV------ 1704
Query: 1049 ACPCLPNVTGLACDRCADGYWNLVPGRGCQSCDCDPRTSQSSHCDQLTG--QCPCKLGYG 1106
C N G C+RC +GY+ C++C C S ++ C G +C CK GY
Sbjct: 1705 --NCQHNTAGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYT 1762
Query: 1107 GKRCSECQENYYGDPP---GRCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDRCAR 1163
G +C C Y+G+P G C PC CN G Q C P TG C +E + C
Sbjct: 1763 GTQCERCAPGYFGNPQKFGGSCQPCSCNSNG-QLGSCHPLTGDCINQEPKDSSPAEEC-- 1819
Query: 1164 GHSQEFPTCLQCHL-CFDQWDHTISSLSKAVQGLMRLAANMEDKRETLPVCEADFKDLRG 1222
+ +C+ L + + +QGL A +E R E KDLR
Sbjct: 1820 ---DDCDSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRH----METQAKDLR- 1871
Query: 1223 NVSEIERILKHPVFPSGKFLKVKDYHDSVRRQIMQLNEQLKAVYE--------FQDLKDT 1274
++L + S K+ + + R++ LN++ + + E Q L +
Sbjct: 1872 -----NQLLNYRSAISNHGSKI----EGLERELTDLNQEFETLQEKAQVNSRKAQTLNNN 1922
Query: 1275 IERAKNEA 1282
+ RA A
Sbjct: 1923 VNRATQSA 1930
Score = 96.3 bits (238), Expect = 2e-19
Identities = 56/191 (29%), Positives = 79/191 (41%), Gaps = 31/191 (16%)
Query: 356 GGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSHSDPA 415
GG C CQ N G+ C RC Y P C PC C +C
Sbjct: 1282 GGQCP-CQPNVIGRQCTRCATGHYGFP--------RCKPCSC------GRRLCEE----- 1321
Query: 416 LGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLT--CDVDTG 473
+ GQC C +C+ C+ + + GC+ C+C+ G++ CD D+G
Sbjct: 1322 ---MTGQCRCPPRTVRPQCEVCETHSFSFHPM--AGCEGCNCSRRGTIEAAMPECDRDSG 1376
Query: 474 QCLCLSYVTGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYSNVCSPKNGQCECRPHVTG 533
QC C +TG C+ C G++ C PC+C+ G VC P G C C+ +V G
Sbjct: 1377 QCRCKPRITGRQCDRCASGFYRFPE----CVPCNCNRDGTEPGVCDPGTGACLCKENVEG 1432
Query: 534 RSCSEPAPGYF 544
C+ G F
Sbjct: 1433 TECNVCREGSF 1443
Score = 93.2 bits (230), Expect = 2e-18
Identities = 73/237 (30%), Positives = 89/237 (37%), Gaps = 46/237 (19%)
Query: 273 ECRPMQKMRGDVFSPPGMVHGQCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSC 332
EC P G SP G GQC CQ N G C RC P C+ C
Sbjct: 1267 ECHPTGAT-GPHCSPEG---GQCPCQPNVIGRQCTRCATGHYGFP----------RCKPC 1312
Query: 333 SCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYAC 392
SC R +MT G C C T C+ C + + C
Sbjct: 1313 SCGR---RLCEEMT----------GQCR-CPPRTVRPQCEVCETHSF-----SFHPMAGC 1353
Query: 393 IPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGC 452
C C GTI + P +GQC CK + G +CD+C Y C
Sbjct: 1354 EGCNCSRRGTIEAAM------PECDRDSGQCRCKPRITGRQCDRCASGFYRFPE-----C 1402
Query: 453 QPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGLG-NHLHGCSPCDC 508
PC+CN G+ P + CD TG CLC V G C C G + L +L GC+ C C
Sbjct: 1403 VPCNCNRDGTEPGV-CDPGTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFC 1458
Score = 91.3 bits (225), Expect = 8e-18
Identities = 53/140 (37%), Positives = 64/140 (45%), Gaps = 18/140 (12%)
Query: 788 CQCKPLVVGRCCDRCSTGSYDLGHHG-----CHPCHCHPQGSKDTVCDQVTGQC-PCHGE 841
C C P G C CS G Y H G C PC+C+ ++ C +G C C
Sbjct: 1654 CACPPAYAGDSCQGCSPGYY-RDHKGLYTGRCVPCNCNGHSNQ---CQDGSGICVNCQHN 1709
Query: 842 VSGRRCDRCLAGYFG---FPSCHPCPC---NRFAELCDPETGSC-FNCGGFTTGRNCERC 894
+G C+RC GY+G SC CPC N FA C G +C TG CERC
Sbjct: 1710 TAGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERC 1769
Query: 895 IDGYYGNPSS-GQPCRPCLC 913
GY+GNP G C+PC C
Sbjct: 1770 APGYFGNPQKFGGSCQPCSC 1789
Score = 78.6 bits (192), Expect = 5e-14
Identities = 49/132 (37%), Positives = 57/132 (43%), Gaps = 13/132 (9%)
Query: 763 HDGAVACKCHPQGSVGSS--CSRLGGQC-QCKPLVVGRCCDRCSTGSYDLGHHG-CHPCH 818
H G +C P G S C G C C+ G C+RC G Y HG C C
Sbjct: 1676 HKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRACP 1735
Query: 819 CHPQGSKDTVCDQVTG--QCPCHGEVSGRRCDRCLAGYFGFP-----SCHPCPCNRFAEL 871
C S T C G +C C +G +C+RC GYFG P SC PC CN +L
Sbjct: 1736 CPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQL 1795
Query: 872 --CDPETGSCFN 881
C P TG C N
Sbjct: 1796 GSCHPLTGDCIN 1807
Score = 77.0 bits (188), Expect = 1e-13
Identities = 45/133 (33%), Positives = 57/133 (42%), Gaps = 11/133 (8%)
Query: 423 CLCKENVEGAKCDQCKPNHYGLSATDPLG-CQPCDCNPLGSLPFLTCDVDTGQCL-CLSY 480
C C G C C P +Y G C PC+CN + C +G C+ C
Sbjct: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSN----QCQDGSGICVNCQHN 1709
Query: 481 VTGAHCEECTVGYWGLGNHLHG-CSPCDCDIGGAYSNVCSPKNG--QCECRPHVTGRSCS 537
G HCE C GY+G N +HG C C C +++ C G +C C+ TG C
Sbjct: 1710 TAGEHCERCQEGYYG--NAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCE 1767
Query: 538 EPAPGYFFAPLNF 550
APGYF P F
Sbjct: 1768 RCAPGYFGNPQKF 1780
Score = 72.4 bits (176), Expect = 4e-12
Identities = 38/116 (32%), Positives = 53/116 (45%), Gaps = 6/116 (5%)
Query: 751 CERLIISMSAKLHDGAVACKCHPQGSVGSS--CSRLGGQCQCKPLVVGRCCDRCSTGSYD 808
C+ L ++ + G CKCH G+V + C + G C CK V G CD C G +
Sbjct: 613 CKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFA 672
Query: 809 L---GHHGCHPCHCHPQGSKDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFPSCH 861
L + GC C C G+ ++C +G C C V G+ C R Y+ FP H
Sbjct: 673 LEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQRPENNYY-FPDLH 727
Score = 69.7 bits (169), Expect = 2e-11
Identities = 50/192 (26%), Positives = 83/192 (43%), Gaps = 51/192 (26%)
Query: 253 YYALYEMIVRGSCF---CNGHASECRPMQKMRGDVFSPPGMVHGQCV-CQHNTDGPNCER 308
YY ++ + G C CNGH+++C+ G CV CQHNT G +CER
Sbjct: 1672 YYRDHKGLYTGRCVPCNCNGHSNQCQDGS--------------GICVNCQHNTAGEHCER 1717
Query: 309 CKDFFQDAPWRPAADLQDNACRSCSC---NSHSSRCHFDMTTYLASGGLSGGVCEDCQHN 365
C++ + + +CR+C C NS ++ C + G V C+
Sbjct: 1718 CQEGYY-------GNAVHGSCRACPCPHTNSFATGCVVN----------GGDVRCSCKAG 1760
Query: 366 TEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLC 425
G C+RC P ++ +P K +C PC C+ +G + G C + G C+
Sbjct: 1761 YTGTQCERCAPGYFGNPQKFGG---SCQPCSCNSNGQL--GSC--------HPLTGDCIN 1807
Query: 426 KENVEGAKCDQC 437
+E + + ++C
Sbjct: 1808 QEPKDSSPAEEC 1819
Score = 62.0 bits (149), Expect = 5e-09
Identities = 40/154 (25%), Positives = 55/154 (35%), Gaps = 44/154 (28%)
Query: 437 CKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGL 496
CK + L A G PC+C+P G+ C + GQC C V G C C G++G
Sbjct: 1248 CKNSARSLVAFYHKGALPCECHPTGATG-PHCSPEGGQCPCQPNVIGRQCTRCATGHYGF 1306
Query: 497 G----------------------------------------NHLHGCSPCDCDIGG---A 513
+ + GC C+C G A
Sbjct: 1307 PRCKPCSCGRRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEA 1366
Query: 514 YSNVCSPKNGQCECRPHVTGRSCSEPAPGYFFAP 547
C +GQC C+P +TGR C A G++ P
Sbjct: 1367 AMPECDRDSGQCRCKPRITGRQCDRCASGFYRFP 1400
Score = 46.6 bits (109), Expect = 2e-04
Identities = 25/80 (31%), Positives = 34/80 (42%), Gaps = 6/80 (7%)
Query: 762 LHDGAVACKCHPQGSVGSSCSRLGG--QCQCKPLVVGRCCDRCSTGSYDLGHH---GCHP 816
+H AC C S + C GG +C CK G C+RC+ G + C P
Sbjct: 1727 VHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQP 1786
Query: 817 CHCHPQGSKDTVCDQVTGQC 836
C C+ G + C +TG C
Sbjct: 1787 CSCNSNGQLGS-CHPLTGDC 1805
Score = 43.1 bits (100), Expect = 0.002
Identities = 22/63 (34%), Positives = 30/63 (47%), Gaps = 2/63 (3%)
Query: 751 CERLIISMSAKLHDGAVACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCSTGSY--D 808
CE ++ + G C+C G++ S CS G CQC+ VVG+ C R Y D
Sbjct: 666 CEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQRPENNYYFPD 725
Query: 809 LGH 811
L H
Sbjct: 726 LHH 728
Score = 35.4 bits (80), Expect = 0.49
Identities = 25/113 (22%), Positives = 55/113 (48%), Gaps = 1/113 (0%)
Query: 1610 QTREMKSELELAKQRSGLEDGLSLLQTKLQRHQDHAVNAKVQAESAQHQAGSLEKEFVEL 1669
Q R +KS+L+ +GL + + ++T+ + ++ +N + + + LE+E +L
Sbjct: 1839 QLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTDL 1898
Query: 1670 KKQYAILQRKTSTTGLTKETL-GKVKQLKDAAEKLAGDTEAKIRRITDLERKI 1721
+++ LQ K +TL V + +A++L + IR + L ++I
Sbjct: 1899 NQEFETLQEKAQVNSRKAQTLNNNVNRATQSAKELDVKIKNVIRNVHILLKQI 1951
Score = 33.9 bits (76), Expect = 1.4
Identities = 28/104 (26%), Positives = 42/104 (40%), Gaps = 29/104 (27%)
Query: 244 RQNDSLDKYYYALYEMIVRGSCFCNGHASECRPMQKMRGDVFSPPGMVH---GQCVCQHN 300
RQ D +Y E + C CN +E PG+ G C+C+ N
Sbjct: 1387 RQCDRCASGFYRFPECV---PCNCNRDGTE--------------PGVCDPGTGACLCKEN 1429
Query: 301 TDGPNCERCKD--FFQDAPWRPAADLQDNACRSCSCNSHSSRCH 342
+G C C++ F D A+L+ C SC C +++CH
Sbjct: 1430 VEGTECNVCREGSFHLDP-----ANLK--GCTSCFCFGVNNQCH 1466
Score = 33.5 bits (75), Expect = 1.9
Identities = 27/113 (23%), Positives = 46/113 (40%), Gaps = 21/113 (18%)
Query: 268 NGHASECRPMQKMRGDVFSPPGMVHG---QCVCQHNTDGPNCERCKDFFQDAPWRPAADL 324
N CR + F+ +V+G +C C+ G CERC + P +
Sbjct: 1725 NAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQK----- 1779
Query: 325 QDNACRSCSCNSHS--SRCHFDMTTYLASGGLSGG-VCEDCQHNTEGQHCDRC 374
+C+ CSCNS+ CH L+G + ++ + ++ + CD C
Sbjct: 1780 FGGSCQPCSCNSNGQLGSCH----------PLTGDCINQEPKDSSPAEECDDC 1822
>gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens]
Length = 3277
Score = 270 bits (691), Expect = 7e-72
Identities = 175/571 (30%), Positives = 269/571 (47%), Gaps = 93/571 (16%)
Query: 29 HPTTGDLLVGRNTQLMASSTCG-------LSRAQKYCIL----------SYLEGEQKCFI 71
HPT +L ++ A++TCG + + YC L ++G Q C
Sbjct: 48 HPTYFNL--AEAARIWATATCGERGPGEGRPQPELYCKLVGGPTAPGSGHTIQG-QFCDY 104
Query: 72 CDSRFPYDPYDQPNSHTIENVIVSFEPDREKKWWQSE-----NGLDHVSIRLDLEALFRF 126
C+S D +H + N I D ++WWQS + V++ LDL LF
Sbjct: 105 CNSE------DPRKAHPVTNAI-----DGSERWWQSPPLSSGTQYNRVNLTLDLGQLFHV 153
Query: 127 SHLILTFKTF-RPAAMLVERSTDYGHNWKVFKYFAK---DCATSFPNITSGQAQGVGDIV 182
+++++ F RP ++ERS D+G + ++YFA DC F + D++
Sbjct: 154 AYILIKFANSPRPDLWVLERSVDFGSTYSPWQYFAHSKVDCLKEFGREANMAVTRDDDVL 213
Query: 183 CDSKYSDIEPSTGGEVVLKVLDPSFEIEN-PYSPYIQDLVTLTNLRINFTKLHTLGDALL 241
C ++YS I P GEVV+ +++ +N +S +++ TN+R+ F + +TL L+
Sbjct: 214 CVTEYSRIVPLENGEVVVSLINGRPGAKNFTFSHTLREFTKATNIRLRFLRTNTLLGHLI 273
Query: 242 GRRQNDSL--DKYYYALYEMIVRGSCFCNGHASECRPMQKMRGDVFSPPGMVHGQCVCQH 299
+ Q D +YYY++ ++ + G C CNGHA C ++ +P + +C CQH
Sbjct: 274 SKAQRDPTVTRRYYYSIKDISIGGQCVCNGHAEVC--------NINNPEKLF--RCECQH 323
Query: 300 NTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASGGLS---- 355
+T G C+RC + WRPAA Q + C +C+C+ H+S C++D L+
Sbjct: 324 HTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQASLNTQGI 383
Query: 356 ---GGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSHS 412
GGVC +CQHNT G +C++C +YR + P CIPC CDP+ H+
Sbjct: 384 YAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPE----------HA 433
Query: 413 DPALGSVAGQCLCKENVEGAKCDQCKPNHYGL--------------SATDPLG--CQPCD 456
D +G+C CK N G C++C +Y S+ DP+ + CD
Sbjct: 434 D-GCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCD 492
Query: 457 CNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYSN 516
CN G LP + CD G+CLC V G C+ C G++ C C C G+Y
Sbjct: 493 CNLEGVLPEI-CDAH-GRCLCRPGVEGPRCDTCRSGFYSFPI----CQACWCSALGSYQM 546
Query: 517 VCSPKNGQCECRPHVTGRSCSEPAPGYFFAP 547
CS GQCECRP VTG+ C G + P
Sbjct: 547 PCSSVTGQCECRPGVTGQRCDRCLSGAYDFP 577
Score = 170 bits (430), Expect = 1e-41
Identities = 132/446 (29%), Positives = 170/446 (38%), Gaps = 81/446 (18%)
Query: 835 QCPCHGEVSGRRCDRCLAGYFG----------FPSCHPCPCNRFAELC--DPET------ 876
+C C G CDRC GY C C C+ A C DP+
Sbjct: 318 RCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQAS 377
Query: 877 ----------GSCFNCGGFTTGRNCERCIDGYY---GNP-SSGQPCRPCLCPDDPSSNQY 922
G C NC T G NCE+C GYY G P + C PC C DP
Sbjct: 378 LNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSC--DPEH--- 432
Query: 923 FAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCA----------- 971
A C Q C+C + G C +C+ G+Y P P P +
Sbjct: 433 -ADGCEQGSGR----CHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGD 487
Query: 972 ---CNNNIDVTDPESCSRVTGECLRCLHNTQGANCQLCKPGHYGSALNQTCRRCSCHASG 1028
C+ N++ PE C G CL C +G C C+ G Y + C+ C C A G
Sbjct: 488 IKGCDCNLEGVLPEICD-AHGRCL-CRPGVEGPRCDTCRSGFYSFPI---CQACWCSALG 542
Query: 1029 VSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCADGYWNLVPGRGCQSCDCDPRTSQ 1088
M C VTG C C P VTG CDRC G ++ +G S CDP +
Sbjct: 543 SYQMPC---------SSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSA-CDPAGTI 592
Query: 1089 SSHCDQLTGQCPCKLGYGGKRCSECQENYYG---DPPGRCIPCDCNRAGTQKPI--CDPD 1143
+S+ G C CKL G CS C+ Y+ + P C C C++AGT C
Sbjct: 593 NSNL----GYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQG 648
Query: 1144 TGMCRCREGVSGQRCDRCARGH-SQEFPTCLQCHLCFDQWDHTISSLSKAVQGLMRLAAN 1202
G C C+ V G CD C G+ + E C C +SS+ G+ + +
Sbjct: 649 DGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREH 708
Query: 1203 MEDKRETLPVCEADFKDLRGNVSEIE 1228
+ K P F DL EIE
Sbjct: 709 VVGKVCQRPENNYYFPDLHHMKYEIE 734
Score = 166 bits (421), Expect = 1e-40
Identities = 126/423 (29%), Positives = 165/423 (39%), Gaps = 73/423 (17%)
Query: 787 QCQCKPLVVGRCCDRCSTG---------SYDLGHHGCHPCHCHPQGSK-----DTVCDQV 832
+C+C+ G CDRC TG +++ H C C+CH S D Q
Sbjct: 318 RCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHE-CEACNCHGHASNCYYDPDVERQQA 376
Query: 833 T----------GQC-PCHGEVSGRRCDRCLAGY---FGFP-----SCHPCPCN-RFAELC 872
+ G C C +G C++C GY +G P C PC C+ A+ C
Sbjct: 377 SLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHADGC 436
Query: 873 DPETGSCFNCGGFTTGRNCERCIDGYYGNPSSGQ-PCRPCLCP--DDPSSNQYFAHSC-- 927
+ +G C +C G NCE+C GYY P + P P P +DP + C
Sbjct: 437 EQGSGRC-HCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNL 495
Query: 928 ---YQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTDPESC 984
+ + C C G G +C C +GFY P CQ C C+ P C
Sbjct: 496 EGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFP-----ICQACWCSALGSYQMP--C 548
Query: 985 SRVTGECLRCLHNTQGANCQLCKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCD 1044
S VTG+C C G C C G Y H G S C P G +
Sbjct: 549 SSVTGQC-ECRPGVTGQRCDRCLSGAYDFP----------HCQG-SSSACDPAG---TIN 593
Query: 1045 PVTGACPCLPNVTGLACDRCADGYWNLVPGR--GCQSCDCDP--RTSQSSHCDQLTGQCP 1100
G C C +V G C RC YWNL GC C C S + C Q G C
Sbjct: 594 SNLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCH 653
Query: 1101 CKLGYGGKRCSECQENYYGDPPGR---CIPCDCNRAGTQKPICDPDTGMCRCREGVSGQR 1157
CK GG C C++ Y+ C C C+ G +C +G+C+CRE V G+
Sbjct: 654 CKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKV 713
Query: 1158 CDR 1160
C R
Sbjct: 714 CQR 716
Score = 163 bits (413), Expect = 1e-39
Identities = 92/279 (32%), Positives = 129/279 (46%), Gaps = 50/279 (17%)
Query: 292 HGQCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLAS 351
HG+C+C+ +GP C+ C+ F P C++C C++ S Y
Sbjct: 506 HGRCLCRPGVEGPRCDTCRSGFYSFP----------ICQACWCSALGS--------YQMP 547
Query: 352 GGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCE-----CDPDGTISGG 406
G CE C+ GQ CDRC +S Y C+ CDP GTI+
Sbjct: 548 CSSVTGQCE-CRPGVTGQRCDRC-----------LSGAYDFPHCQGSSSACDPAGTINSN 595
Query: 407 ICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFL 466
+ G C CK +VEG C +CK ++ L +P GC C C+ G++
Sbjct: 596 L-------------GYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGT 642
Query: 467 -TCDVDTGQCLCLSYVTGAHCEECTVGYWGLG-NHLHGCSPCDCDIGGAYSNVCSPKNGQ 524
C G C C S+V G C+ C GY+ L ++ GC C CDIGGA S++CS +G
Sbjct: 643 GECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGV 702
Query: 525 CECRPHVTGRSCSEPAPGYFFAPLNFYLYEAEEATTLQG 563
C+CR HV G+ C P Y+F L+ YE E+ +T G
Sbjct: 703 CQCREHVVGKVCQRPENNYYFPDLHHMKYEIEDGSTPNG 741
Score = 148 bits (374), Expect = 4e-35
Identities = 110/373 (29%), Positives = 144/373 (38%), Gaps = 76/373 (20%)
Query: 785 GGQC-QCKPLVVGRCCDRCSTGSYDL------GHHGCHPCHCHPQGSKDTVCDQVTGQCP 837
GG C C+ G C++C+ G Y GC PC C P+ + C+Q +G+C
Sbjct: 387 GGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHADG--CEQGSGRCH 444
Query: 838 CHGEVSGRRCDRCLAGYFGFPSC---------------------HPCPCNR---FAELCD 873
C G C++C GY+ FP C C CN E+CD
Sbjct: 445 CKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICD 504
Query: 874 PETGSCFNCGGFTTGRNCERCIDGYYGNPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWS 933
G C C G C+ C G+Y P C+ C C A YQ S
Sbjct: 505 AH-GRCL-CRPGVEGPRCDTCRSGFYSFPI----CQACWCS---------ALGSYQMPCS 549
Query: 934 SDV-ICNCLQGYTGTQCGECSTGFYGNPRISGAP--CQPCAC-NNNIDVTDPESCSRVTG 989
S C C G TG +C C +G Y P G+ C P N+N+ G
Sbjct: 550 SVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAGTINSNL------------G 597
Query: 990 ECLRCLHNTQGANCQLCKPGHYGSALNQT--CRRCSCHASGVSPMECPPGGGACLCDPVT 1047
C +C + +G C CK ++ C C CH +G G C
Sbjct: 598 YC-QCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTV-------SGTGECRQGD 649
Query: 1048 GACPCLPNVTGLACDRCADGYWNLVPGR--GCQSCDCDPRTSQSSHCDQLTGQCPCKLGY 1105
G C C +V G +CD C DGY+ L GCQ C CD + SS C +G C C+
Sbjct: 650 GDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHV 709
Query: 1106 GGKRCSECQENYY 1118
GK C + NYY
Sbjct: 710 VGKVCQRPENNYY 722
Score = 147 bits (372), Expect = 7e-35
Identities = 123/428 (28%), Positives = 177/428 (41%), Gaps = 61/428 (14%)
Query: 567 LGSETFGQSPAVHVVLGEPVPGNPVTWTGPGFARVLPGAGLRFAVNNI------PFPVDF 620
L ET + + V+ G P P P + P VLPG L+ N + P +
Sbjct: 1070 LAHETPPTALILDVLSGRPFPHLPQQ-SSPS-VDVLPGVTLKAPQNQVTLRGRVPHLGRY 1127
Query: 621 TIAIHYETQSAADWTVQIVVN---PPGGSEHC--IPKTLQSKPQSFALPAATRIMLLPTP 675
IH+ + + Q+ V+ P GS H P L + Q A +
Sbjct: 1128 VFVIHFYQAAHPTFPAQVSVDGGWPRAGSFHASFCPHVLGCRDQVIAEGQIEFDIS---- 1183
Query: 676 ICLEPDVQYSIDVYFSQPLQGESHAHSHVLVDSLGLIPQINSLENFCSKQDLDEYQ--LH 733
EP+V ++ V +G+S VLV +P N K+ +D+ +
Sbjct: 1184 ---EPEVAATVKVP-----EGKSLVLVRVLV-----VPAENYDYQILHKKSMDKSLEFIT 1230
Query: 734 NCVEIASAMGPQVLPGACERLIISMSAKLHDGAVACKCHPQGSVGSSCSRLGGQCQCKPL 793
NC + + + PQ C+ S+ A H GA+ C+CHP G+ G CS GGQC C+P
Sbjct: 1231 NCGKNSFYLDPQTASRFCKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPN 1290
Query: 794 VVGRCCDRCSTGSYDLGHHGCHPCHCHPQGSKDTVCDQVTGQCPCHGEVSGRRCDRCLAG 853
V+GR C RC+TG Y G C PC C + +C+++TGQC C +C+ C
Sbjct: 1291 VIGRQCTRCATGHY--GFPRCKPCSCGRR-----LCEEMTGQCRCPPRTVRPQCEVCETH 1343
Query: 854 YFGF---PSCHPCPCNRFAEL------CDPETGSCFNCGGFTTGRNCERCIDGYYGNPSS 904
F F C C C+R + CD ++G C C TGR C+RC G+Y P
Sbjct: 1344 SFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQC-RCKPRITGRQCDRCASGFYRFPE- 1401
Query: 905 GQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISG 964
C PC C D + C + C C + GT+C C G + +
Sbjct: 1402 ---CVPCNCNRDGTE----PGVCDPGTGA----CLCKENVEGTECNVCREGSFHLDPANL 1450
Query: 965 APCQPCAC 972
C C C
Sbjct: 1451 KGCTSCFC 1458
Score = 144 bits (364), Expect = 6e-34
Identities = 83/236 (35%), Positives = 101/236 (42%), Gaps = 21/236 (8%)
Query: 792 PLVVGRCCDRCSTGSYDLGHHGCHPCHCHPQGSKDTVCDQVTGQCPCHGEVSGRRCDRCL 851
P R C + H G PC CHP G+ C GQCPC V GR+C RC
Sbjct: 1241 PQTASRFCKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCA 1300
Query: 852 AGYFGFPSCHPCPCNRFAELCDPETGSCFNCGGFTTGRNCERC-IDGYYGNPSSGQPCRP 910
G++GFP C PC C R LC+ TG C C T CE C + +P +G C
Sbjct: 1301 TGHYGFPRCKPCSCGR--RLCEEMTGQC-RCPPRTVRPQCEVCETHSFSFHPMAG--CEG 1355
Query: 911 CLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPC 970
C C S + + C C TG QC C++GFY P C PC
Sbjct: 1356 CNC-----SRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFPE-----CVPC 1405
Query: 971 ACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQLCKPG--HYGSALNQTCRRCSC 1024
CN D T+P C TG CL C N +G C +C+ G H A + C C C
Sbjct: 1406 NCNR--DGTEPGVCDPGTGACL-CKENVEGTECNVCREGSFHLDPANLKGCTSCFC 1458
Score = 141 bits (356), Expect = 5e-33
Identities = 84/252 (33%), Positives = 113/252 (44%), Gaps = 43/252 (17%)
Query: 947 TQCGECSTGFYGNPRISGAPCQ---------------PCACNNNIDVTDPESCSRVTGEC 991
T CG+ S FY +P+ + C+ PC C+ T P CS G+C
Sbjct: 1230 TNCGKNS--FYLDPQTASRFCKNSARSLVAFYHKGALPCECHPT-GATGPH-CSPEGGQC 1285
Query: 992 LRCLHNTQGANCQLCKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACP 1051
C N G C C GHYG C+ CSC G LC+ +TG C
Sbjct: 1286 -PCQPNVIGRQCTRCATGHYGFP---RCKPCSC--------------GRRLCEEMTGQCR 1327
Query: 1052 CLPNVTGLACDRCADGYWNLVPGRGCQSCDCDPRTSQSS---HCDQLTGQCPCKLGYGGK 1108
C P C+ C ++ P GC+ C+C R + + CD+ +GQC CK G+
Sbjct: 1328 CPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGR 1387
Query: 1109 RCSECQENYYGDPPGRCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDRCARGHSQE 1168
+C C +Y P C+PC+CNR GT+ +CDP TG C C+E V G C+ C G
Sbjct: 1388 QCDRCASGFYRFP--ECVPCNCNRDGTEPGVCDPGTGACLCKENVEGTECNVCREGSFHL 1445
Query: 1169 FPTCLQ-CHLCF 1179
P L+ C CF
Sbjct: 1446 DPANLKGCTSCF 1457
Score = 140 bits (354), Expect = 8e-33
Identities = 98/332 (29%), Positives = 130/332 (39%), Gaps = 50/332 (15%)
Query: 863 CPCNRFAELCD---PETGSCFNCGGFTTGRNCERCIDGYYGNPSSGQP--------CRPC 911
C CN AE+C+ PE C T G C+RC GY N +P C C
Sbjct: 299 CVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGY--NQRRWRPAAWEQSHECEAC 356
Query: 912 LCPD-------DPSSNQYFAHSCYQNLWSSDVIC-NCLQGYTGTQCGECSTGFY---GNP 960
C DP + A Q +++ +C NC G C +C+ G+Y G P
Sbjct: 357 NCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVP 416
Query: 961 RISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQLCKPGHYGSALNQTCR 1020
+ C PC+C D + C + +G C C N G NC+ C G+Y C
Sbjct: 417 VDAPDGCIPCSC----DPEHADGCEQGSGRC-HCKPNFHGDNCEKCAIGYYNFPF---CL 468
Query: 1021 RCSCHASGVSPMECPPGGGACLCD-----------PVTGACPCLPNVTGLACDRCADGYW 1069
R E P G CD G C C P V G CD C G++
Sbjct: 469 RIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFY 528
Query: 1070 NLVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSECQENYYGDPPGRCIPCD 1129
+ CQ+C C S C +TGQC C+ G G+RC C Y P +
Sbjct: 529 SFPI---CQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSA 585
Query: 1130 CNRAGTQKPICDPDTGMCRCREGVSGQRCDRC 1161
C+ AGT + + G C+C+ V G C RC
Sbjct: 586 CDPAGT----INSNLGYCQCKLHVEGPTCSRC 613
Score = 137 bits (346), Expect = 7e-32
Identities = 87/332 (26%), Positives = 134/332 (40%), Gaps = 56/332 (16%)
Query: 764 DGAVACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHGCHP------- 816
DG + C C P+ + G C + G+C CKP G C++C+ G Y+ P
Sbjct: 421 DGCIPCSCDPEHADG--CEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTP 478
Query: 817 ------------CHCHPQGSKDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFPSCHPCP 864
C C+ +G +CD G+C C V G RCD C +G++ FP C C
Sbjct: 479 SSEDPVAGDIKGCDCNLEGVLPEICD-AHGRCLCRPGVEGPRCDTCRSGFYSFPICQACW 537
Query: 865 CNRFAEL---CDPETGSCFNCGGFTTGRNCERCIDGYYGNPSSGQPCRPCLCPDDPSSNQ 921
C+ C TG C C TG+ C+RC+ G Y P C+ DP+
Sbjct: 538 CSALGSYQMPCSSVTGQC-ECRPGVTGQRCDRCLSGAYDFPH----CQGSSSACDPAG-- 590
Query: 922 YFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTDP 981
+ S+ C C G C C ++ + + + C C C+ V+
Sbjct: 591 --------TINSNLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGT 642
Query: 982 ESCSRVTGECLRCLHNTQGANCQLCKPGHYGSALNQT----CRRCSCHASGVSPMECPPG 1037
C + G+C C + G +C C+ G++ AL ++ C+ C C G
Sbjct: 643 GECRQGDGDC-HCKSHVGGDSCDTCEDGYF--ALEKSNYFGCQGCQCDIGGAL------- 692
Query: 1038 GGACLCDPVTGACPCLPNVTGLACDRCADGYW 1069
+ +C +G C C +V G C R + Y+
Sbjct: 693 --SSMCSGPSGVCQCREHVVGKVCQRPENNYY 722
Score = 135 bits (340), Expect = 4e-31
Identities = 68/163 (41%), Positives = 85/163 (52%), Gaps = 16/163 (9%)
Query: 836 CPCHGEVSGRRCDRCLAGYFGFPS------CHPCPCNRFAELCDPETGSCFNCGGFTTGR 889
C C +G C C GY+ C PC CN + C +G C NC T G
Sbjct: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGE 1713
Query: 890 NCERCIDGYYGNPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQC 949
+CERC +GYYGN G CR C CP S FA C N DV C+C GYTGTQC
Sbjct: 1714 HCERCQEGYYGNAVHGS-CRACPCPHTNS----FATGCVVN--GGDVRCSCKAGYTGTQC 1766
Query: 950 GECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECL 992
C+ G++GNP+ G CQPC+CN+N + SC +TG+C+
Sbjct: 1767 ERCAPGYFGNPQKFGGSCQPCSCNSNGQL---GSCHPLTGDCI 1806
Score = 118 bits (295), Expect = 6e-26
Identities = 179/815 (21%), Positives = 311/815 (38%), Gaps = 148/815 (18%)
Query: 937 ICNCLQGYTGTQCGECSTGFYGNPR-ISGAPCQPCACNNNIDVTDPESCSRVTGECLRCL 995
IC C Y G C CS G+Y + + + C PC CN + + C +G C+ C
Sbjct: 1653 ICACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSN-----QCQDGSGICVNCQ 1707
Query: 996 HNTQGANCQLCKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPN 1055
HNT G +C+ C+ G+YG+A++ +CR C C + C GG C C
Sbjct: 1708 HNTAGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDV-------RCSCKAG 1760
Query: 1056 VTGLACDRCADGYWNLVP--GRGCQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSEC 1113
TG C+RCA GY+ G CQ C C+ Q C LTG C + EC
Sbjct: 1761 YTGTQCERCAPGYFGNPQKFGGSCQPCSCN-SNGQLGSCHPLTGDCINQEPKDSSPAEEC 1819
Query: 1114 QENYYGDPPGRCIPC------DCNRAGTQKPICDPDTGMCRCREGVSGQRCDRCARGHSQ 1167
+ C C D G Q + G+ Q H +
Sbjct: 1820 DD---------CDSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQ------MRHME 1864
Query: 1168 EFPTCLQCHLCFDQWDHTISSLSKAVQGLMRLAANMEDKRETL----PVCEADFKDLRGN 1223
L+ L + IS+ ++GL R ++ + ETL V + L N
Sbjct: 1865 TQAKDLRNQLL--NYRSAISNHGSKIEGLERELTDLNQEFETLQEKAQVNSRKAQTLNNN 1922
Query: 1224 VSEIERILKHPVFPSGKFLKVKDYHDSVRRQIMQLNE----QLKAVYEFQDLKDTIERAK 1279
V+ + S K L VK +V R + LN Q E L ++I +
Sbjct: 1923 VNRATQ--------SAKELDVK--IKNVIRNVHMLNRIRTWQKTHQGENNGLANSIRDSL 1972
Query: 1280 NEADLLLEDLQEEIDLQSSVLNASIADSSENIKKYYHISSSAEKKINETSSTINTSANTR 1339
NE + L DL+ + ++ + + EN + + ++++ E IN+ +
Sbjct: 1973 NEYEAKLSDLRARLQEAAAQAKQANGLNQENERAL----GAIQRQVKE----INSLQSDF 2024
Query: 1340 NDLLTILDTLTSKGNLSLERLKQIKIPDIQILNEKVCGDPGNVPCVPLPCGGALCTGRKG 1399
LT D+ + N++L+ +++ Q EK+ +L R+
Sbjct: 2025 TKYLTTADSSLLQTNIALQLMEK-----SQKEYEKL--------------AASLNEARQ- 2064
Query: 1400 HRKCRGPGCHGSLTLSTNALQKAQEAKSIIRNLDKQVRGLKNQIESISEQAEVSKNNALQ 1459
L+ L ++ S++ +K R L + +++Q E K NA
Sbjct: 2065 -----------ELSDKVRELSRSAGKTSLVEEAEKHARSL----QELAKQLEEIKRNA-- 2107
Query: 1460 LREKLGNIRNQSDSEEENINLFIKKVKNFLLEENVPPEDIEKVANGVLDIHLPIPSQNLT 1519
++L + + ENI IK ++ N E V+ LP ++ L+
Sbjct: 2108 SGDELVRCAVDAATAYENILNAIKAAED---AANRAASASESALQTVIKEDLPRKAKTLS 2164
Query: 1520 DELVKIQKHMQLCEDYRTDENRLNEEADGAQKLLVKAKAAEKAANILLNLDKTLNQLQQA 1579
++ ++L EA QK K ++ + L NL +TLN +
Sbjct: 2165 -----------------SNSDKLLNEAKMTQK-----KLKQEVSPALNNLQQTLNIV--- 2199
Query: 1580 QITQGRANSTITQLTANITKIKKNVLQAENQTREMKSELELAKQ-RSGLEDGLSLLQTKL 1638
+ + ++ +T L + I++ + A KS + A + DGL+ +QT +
Sbjct: 2200 TVQKEVIDTNLTTLRDGLHGIQRGDIDA--MISSAKSMVRKANDITDEVLDGLNPIQTDV 2257
Query: 1639 QRHQD-----HAVNAKVQAESAQHQAGSLEKEFVELKKQYAILQRKTSTTGLTKETLGKV 1693
+R +D + K A + L + +L ++ + ++ G + + ++
Sbjct: 2258 ERIKDTYGRTQNEDFKKALTDADNSVNKLTNKLPDLWRKIESINQQLLPLGNISDNMDRI 2317
Query: 1694 KQL----KDAAEKLA------GDTEAKIRRITDLE 1718
++L +DAA K+A G + ++R DLE
Sbjct: 2318 RELIQQARDAASKVAVPMRFNGKSGVEVRLPNDLE 2352
Score = 102 bits (253), Expect = 4e-21
Identities = 56/195 (28%), Positives = 84/195 (43%), Gaps = 29/195 (14%)
Query: 295 CVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASGGL 354
C C G +C+ C + +R L C C+CN HS++C
Sbjct: 1654 CACPPAYAGDSCQGCSPGY----YRDHKGLYTGRCVPCNCNGHSNQCQD----------- 1698
Query: 355 SGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSHSDP 414
G+C +CQHNT G+HC+RC+ +Y + + +C C C + + G V+ D
Sbjct: 1699 GSGICVNCQHNTAGEHCERCQEGYYGNAVHG-----SCRACPCPHTNSFATGCVVNGGDV 1753
Query: 415 ALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQ 474
+C CK G +C++C P ++G CQPC CN G L +C TG
Sbjct: 1754 -------RCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLG--SCHPLTGD 1804
Query: 475 CLCLSYVTGAHCEEC 489
C+ + EEC
Sbjct: 1805 CINQEPKDSSPAEEC 1819
Score = 96.3 bits (238), Expect = 2e-19
Identities = 56/191 (29%), Positives = 79/191 (41%), Gaps = 31/191 (16%)
Query: 356 GGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSHSDPA 415
GG C CQ N G+ C RC Y P C PC C +C
Sbjct: 1282 GGQCP-CQPNVIGRQCTRCATGHYGFP--------RCKPCSC------GRRLCEE----- 1321
Query: 416 LGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLT--CDVDTG 473
+ GQC C +C+ C+ + + GC+ C+C+ G++ CD D+G
Sbjct: 1322 ---MTGQCRCPPRTVRPQCEVCETHSFSFHPM--AGCEGCNCSRRGTIEAAMPECDRDSG 1376
Query: 474 QCLCLSYVTGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYSNVCSPKNGQCECRPHVTG 533
QC C +TG C+ C G++ C PC+C+ G VC P G C C+ +V G
Sbjct: 1377 QCRCKPRITGRQCDRCASGFYRFPE----CVPCNCNRDGTEPGVCDPGTGACLCKENVEG 1432
Query: 534 RSCSEPAPGYF 544
C+ G F
Sbjct: 1433 TECNVCREGSF 1443
Score = 93.2 bits (230), Expect = 2e-18
Identities = 73/237 (30%), Positives = 89/237 (37%), Gaps = 46/237 (19%)
Query: 273 ECRPMQKMRGDVFSPPGMVHGQCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSC 332
EC P G SP G GQC CQ N G C RC P C+ C
Sbjct: 1267 ECHPTGAT-GPHCSPEG---GQCPCQPNVIGRQCTRCATGHYGFP----------RCKPC 1312
Query: 333 SCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYAC 392
SC R +MT G C C T C+ C + + C
Sbjct: 1313 SCGR---RLCEEMT----------GQCR-CPPRTVRPQCEVCETHSF-----SFHPMAGC 1353
Query: 393 IPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGC 452
C C GTI + P +GQC CK + G +CD+C Y C
Sbjct: 1354 EGCNCSRRGTIEAAM------PECDRDSGQCRCKPRITGRQCDRCASGFYRFPE-----C 1402
Query: 453 QPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGLG-NHLHGCSPCDC 508
PC+CN G+ P + CD TG CLC V G C C G + L +L GC+ C C
Sbjct: 1403 VPCNCNRDGTEPGV-CDPGTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFC 1458
Score = 91.3 bits (225), Expect = 8e-18
Identities = 53/140 (37%), Positives = 64/140 (45%), Gaps = 18/140 (12%)
Query: 788 CQCKPLVVGRCCDRCSTGSYDLGHHG-----CHPCHCHPQGSKDTVCDQVTGQC-PCHGE 841
C C P G C CS G Y H G C PC+C+ ++ C +G C C
Sbjct: 1654 CACPPAYAGDSCQGCSPGYY-RDHKGLYTGRCVPCNCNGHSNQ---CQDGSGICVNCQHN 1709
Query: 842 VSGRRCDRCLAGYFG---FPSCHPCPC---NRFAELCDPETGSC-FNCGGFTTGRNCERC 894
+G C+RC GY+G SC CPC N FA C G +C TG CERC
Sbjct: 1710 TAGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERC 1769
Query: 895 IDGYYGNPSS-GQPCRPCLC 913
GY+GNP G C+PC C
Sbjct: 1770 APGYFGNPQKFGGSCQPCSC 1789
Score = 78.6 bits (192), Expect = 5e-14
Identities = 49/132 (37%), Positives = 57/132 (43%), Gaps = 13/132 (9%)
Query: 763 HDGAVACKCHPQGSVGSS--CSRLGGQC-QCKPLVVGRCCDRCSTGSYDLGHHG-CHPCH 818
H G +C P G S C G C C+ G C+RC G Y HG C C
Sbjct: 1676 HKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRACP 1735
Query: 819 CHPQGSKDTVCDQVTG--QCPCHGEVSGRRCDRCLAGYFGFP-----SCHPCPCNRFAEL 871
C S T C G +C C +G +C+RC GYFG P SC PC CN +L
Sbjct: 1736 CPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQL 1795
Query: 872 --CDPETGSCFN 881
C P TG C N
Sbjct: 1796 GSCHPLTGDCIN 1807
Score = 77.0 bits (188), Expect = 1e-13
Identities = 45/133 (33%), Positives = 57/133 (42%), Gaps = 11/133 (8%)
Query: 423 CLCKENVEGAKCDQCKPNHYGLSATDPLG-CQPCDCNPLGSLPFLTCDVDTGQCL-CLSY 480
C C G C C P +Y G C PC+CN + C +G C+ C
Sbjct: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSN----QCQDGSGICVNCQHN 1709
Query: 481 VTGAHCEECTVGYWGLGNHLHG-CSPCDCDIGGAYSNVCSPKNG--QCECRPHVTGRSCS 537
G HCE C GY+G N +HG C C C +++ C G +C C+ TG C
Sbjct: 1710 TAGEHCERCQEGYYG--NAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCE 1767
Query: 538 EPAPGYFFAPLNF 550
APGYF P F
Sbjct: 1768 RCAPGYFGNPQKF 1780
Score = 72.4 bits (176), Expect = 4e-12
Identities = 38/116 (32%), Positives = 53/116 (45%), Gaps = 6/116 (5%)
Query: 751 CERLIISMSAKLHDGAVACKCHPQGSVGSS--CSRLGGQCQCKPLVVGRCCDRCSTGSYD 808
C+ L ++ + G CKCH G+V + C + G C CK V G CD C G +
Sbjct: 613 CKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFA 672
Query: 809 L---GHHGCHPCHCHPQGSKDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFPSCH 861
L + GC C C G+ ++C +G C C V G+ C R Y+ FP H
Sbjct: 673 LEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQRPENNYY-FPDLH 727
Score = 69.7 bits (169), Expect = 2e-11
Identities = 50/192 (26%), Positives = 83/192 (43%), Gaps = 51/192 (26%)
Query: 253 YYALYEMIVRGSCF---CNGHASECRPMQKMRGDVFSPPGMVHGQCV-CQHNTDGPNCER 308
YY ++ + G C CNGH+++C+ G CV CQHNT G +CER
Sbjct: 1672 YYRDHKGLYTGRCVPCNCNGHSNQCQDGS--------------GICVNCQHNTAGEHCER 1717
Query: 309 CKDFFQDAPWRPAADLQDNACRSCSC---NSHSSRCHFDMTTYLASGGLSGGVCEDCQHN 365
C++ + + +CR+C C NS ++ C + G V C+
Sbjct: 1718 CQEGYY-------GNAVHGSCRACPCPHTNSFATGCVVN----------GGDVRCSCKAG 1760
Query: 366 TEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLC 425
G C+RC P ++ +P K +C PC C+ +G + G C + G C+
Sbjct: 1761 YTGTQCERCAPGYFGNPQKFGG---SCQPCSCNSNGQL--GSC--------HPLTGDCIN 1807
Query: 426 KENVEGAKCDQC 437
+E + + ++C
Sbjct: 1808 QEPKDSSPAEEC 1819
Score = 62.0 bits (149), Expect = 5e-09
Identities = 40/154 (25%), Positives = 55/154 (35%), Gaps = 44/154 (28%)
Query: 437 CKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGL 496
CK + L A G PC+C+P G+ C + GQC C V G C C G++G
Sbjct: 1248 CKNSARSLVAFYHKGALPCECHPTGATG-PHCSPEGGQCPCQPNVIGRQCTRCATGHYGF 1306
Query: 497 G----------------------------------------NHLHGCSPCDCDIGG---A 513
+ + GC C+C G A
Sbjct: 1307 PRCKPCSCGRRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEA 1366
Query: 514 YSNVCSPKNGQCECRPHVTGRSCSEPAPGYFFAP 547
C +GQC C+P +TGR C A G++ P
Sbjct: 1367 AMPECDRDSGQCRCKPRITGRQCDRCASGFYRFP 1400
Score = 46.6 bits (109), Expect = 2e-04
Identities = 25/80 (31%), Positives = 34/80 (42%), Gaps = 6/80 (7%)
Query: 762 LHDGAVACKCHPQGSVGSSCSRLGG--QCQCKPLVVGRCCDRCSTGSYDLGHH---GCHP 816
+H AC C S + C GG +C CK G C+RC+ G + C P
Sbjct: 1727 VHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQP 1786
Query: 817 CHCHPQGSKDTVCDQVTGQC 836
C C+ G + C +TG C
Sbjct: 1787 CSCNSNGQLGS-CHPLTGDC 1805
Score = 43.1 bits (100), Expect = 0.002
Identities = 22/63 (34%), Positives = 30/63 (47%), Gaps = 2/63 (3%)
Query: 751 CERLIISMSAKLHDGAVACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCSTGSY--D 808
CE ++ + G C+C G++ S CS G CQC+ VVG+ C R Y D
Sbjct: 666 CEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQRPENNYYFPD 725
Query: 809 LGH 811
L H
Sbjct: 726 LHH 728
Score = 35.8 bits (81), Expect = 0.38
Identities = 25/111 (22%), Positives = 53/111 (47%), Gaps = 1/111 (0%)
Query: 1610 QTREMKSELELAKQRSGLEDGLSLLQTKLQRHQDHAVNAKVQAESAQHQAGSLEKEFVEL 1669
Q R +KS+L+ +GL + + ++T+ + ++ +N + + + LE+E +L
Sbjct: 1839 QLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTDL 1898
Query: 1670 KKQYAILQRKTSTTGLTKETL-GKVKQLKDAAEKLAGDTEAKIRRITDLER 1719
+++ LQ K +TL V + +A++L + IR + L R
Sbjct: 1899 NQEFETLQEKAQVNSRKAQTLNNNVNRATQSAKELDVKIKNVIRNVHMLNR 1949
Score = 33.9 bits (76), Expect = 1.4
Identities = 28/104 (26%), Positives = 42/104 (40%), Gaps = 29/104 (27%)
Query: 244 RQNDSLDKYYYALYEMIVRGSCFCNGHASECRPMQKMRGDVFSPPGMVH---GQCVCQHN 300
RQ D +Y E + C CN +E PG+ G C+C+ N
Sbjct: 1387 RQCDRCASGFYRFPECV---PCNCNRDGTE--------------PGVCDPGTGACLCKEN 1429
Query: 301 TDGPNCERCKD--FFQDAPWRPAADLQDNACRSCSCNSHSSRCH 342
+G C C++ F D A+L+ C SC C +++CH
Sbjct: 1430 VEGTECNVCREGSFHLDP-----ANLK--GCTSCFCFGVNNQCH 1466
Score = 33.5 bits (75), Expect = 1.9
Identities = 27/113 (23%), Positives = 46/113 (40%), Gaps = 21/113 (18%)
Query: 268 NGHASECRPMQKMRGDVFSPPGMVHG---QCVCQHNTDGPNCERCKDFFQDAPWRPAADL 324
N CR + F+ +V+G +C C+ G CERC + P +
Sbjct: 1725 NAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQK----- 1779
Query: 325 QDNACRSCSCNSHS--SRCHFDMTTYLASGGLSGG-VCEDCQHNTEGQHCDRC 374
+C+ CSCNS+ CH L+G + ++ + ++ + CD C
Sbjct: 1780 FGGSCQPCSCNSNGQLGSCH----------PLTGDCINQEPKDSSPAEECDDC 1822
>gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo
sapiens]
Length = 3118
Score = 262 bits (670), Expect = 2e-69
Identities = 129/344 (37%), Positives = 182/344 (52%), Gaps = 28/344 (8%)
Query: 836 CPCHGEVSGRRCDRC------LAGYFGFPSCHPCPCNRFAELCDPETGSCFNCGGFTTGR 889
C C +G C+ C + G C PC C AE CD TG C NC T G
Sbjct: 724 CQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECLNCKDHTGGP 783
Query: 890 NCERCIDGYYGNPSSG--QPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICN-CLQGYTG 946
C++C+ G+YG P+ G + C+PC CP + SN F+ +C+ + S +IC+ C GYTG
Sbjct: 784 YCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNN-FSPTCHLDR-SLGLICDGCPVGYTG 841
Query: 947 TQCGECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQLC 1006
+C C+ G++G P + G CQPC CN+N+D + P SC ++G CL C T G C+LC
Sbjct: 842 PRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELC 901
Query: 1007 KPGHYGSALN-QTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCA 1065
G++G A++ + C+ C C+A G + +C TG C C NV G CD+C
Sbjct: 902 ADGYFGDAVDAKNCQPCRCNAG---------GSFSEVCHSQTGQCECRANVQGQRCDKCK 952
Query: 1066 DGYWNLVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSECQENYYGDPPGRC 1125
G + L RGC C+C+ S+S C++ +GQC C+ G GK+C C Y+ G C
Sbjct: 953 AGTFGLQSARGCVPCNCNSFGSKSFDCEE-SGQCWCQPGVTGKKCDRCAHGYFNFQEGGC 1011
Query: 1126 IPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDRCAR---GHS 1166
C+C+ G CDP TG C C G++C +CA GHS
Sbjct: 1012 TACECSHLGNN---CDPKTGRCICPPNTIGEKCSKCAPNTWGHS 1052
Score = 224 bits (570), Expect = 8e-58
Identities = 151/487 (31%), Positives = 202/487 (41%), Gaps = 84/487 (17%)
Query: 771 CHPQGSVG--SSCSRLGGQC-QCKPLVVGRCCDRCSTGSYDLGHHG----CHPC------ 817
C P G SC + G+C CK G CD+C G Y G C PC
Sbjct: 754 CEPCQCFGHAESCDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNI 813
Query: 818 -------HCHPQGSKDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFP-----SCHPCPC 865
CH S +CD C +G RC+RC GYFG P SC PC C
Sbjct: 814 PSNNFSPTCHLDRSLGLICD------GCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQC 867
Query: 866 NRFAEL-----CDPETGSCFNCGGFTTGRNCERCIDGYYGNPSSGQPCRPCLCPDDPSSN 920
N + CD +GSC C TTGR CE C DGY+G+ + C+PC C ++
Sbjct: 868 NDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRC----NAG 923
Query: 921 QYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTD 980
F+ C+ S C C G +C +C G +G G C PC CN+
Sbjct: 924 GSFSEVCH----SQTGQCECRANVQGQRCDKCKAGTFGLQSARG--CVPCNCNS---FGS 974
Query: 981 PESCSRVTGECLRCLHNTQGANCQLCKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGA 1040
+G+C C G C C G++ + C C C G +
Sbjct: 975 KSFDCEESGQCW-CQPGVTGKKCDRCAHGYF-NFQEGGCTACECSHLGNN---------- 1022
Query: 1041 CLCDPVTGACPCLPNVTGLACDRCADGYWNLVPGRGCQSCDCDPRTSQSSHCDQLTGQCP 1100
CDP TG C C PN G C +CA W GC++C+C S C+ TGQC
Sbjct: 1023 --CDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQCN 1080
Query: 1101 CKLGYGGKRCSECQENYYGDPPGRCIPCDCNRAGTQKPICDPD---------TGMCRCRE 1151
C + G +C+EC ++ P RC CDC GT CD + TG C C+
Sbjct: 1081 CHPKFSGAKCTECSRGHWNYP--RCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKV 1138
Query: 1152 GVSGQRCDRCARG----HSQEFPTCLQCHLCFDQWDHTISSLSKAVQGLMRLAANMEDKR 1207
V G CDRC G ++ C C+ CF T + S+A +GL+R ++ ++
Sbjct: 1139 NVEGIHCDRCRPGKFGLDAKNPLGCSSCY-CFG----TTTQCSEA-KGLIRTWVTLKAEQ 1192
Query: 1208 ETLPVCE 1214
LP+ +
Sbjct: 1193 TILPLVD 1199
Score = 216 bits (551), Expect = 1e-55
Identities = 147/518 (28%), Positives = 240/518 (46%), Gaps = 68/518 (13%)
Query: 35 LLVGRNTQLMASSTCGLSRAQKYC-ILSYLEGEQ----KCFICDSRFPYDPYDQPNS-HT 88
L + N + ++TCG + YC ++ ++ G+ +C IC+ PN H
Sbjct: 44 LNLASNALITTNATCGEKGPEMYCKLVEHVPGQPVRNPQCRICNQNS-----SNPNQRHP 98
Query: 89 IENVIVSFEPDREKKWWQS---ENGLDH--VSIRLDLEALFRFSHLIL-TFKTFRPAAML 142
I N I D + WWQS +NG+++ V+I LDL+ +F+ +++I+ + RP +
Sbjct: 99 ITNAI-----DGKNTWWQSPSIKNGIEYHYVTITLDLQQVFQIAYVIVKAANSPRPGNWI 153
Query: 143 VERSTDYGHNWKVFKYFA---KDCATSF---PNITSGQAQGVGDIVCDSKYSDIEPSTGG 196
+ERS D +K ++Y A +C T + P +++C S YS I P G
Sbjct: 154 LERSLD-DVEYKPWQYHAVTDTECLTLYNIYPRTGPPSYAKDDEVICTSFYSKIHPLENG 212
Query: 197 EVVLKVLDPSFEIENPYSPYIQDLVTLTNLRINFTKLHTLGDALLGRRQNDSLD------ 250
E+ + +++ ++P SP + + + +R+ F ++ TL L+ D +
Sbjct: 213 EIHISLINGRPSADDP-SPELLEFTSARYIRLRFQRIRTLNADLMMFAHKDPREIDPIVT 271
Query: 251 -KYYYALYEMIVRGSCFCNGHASECRPMQKMRGDVFSPPGMVHGQCVCQHNTDGPNCERC 309
+YYY++ ++ V G C C GHA C P+ P +C C+HNT G +C++C
Sbjct: 272 RRYYYSVKDISVGGMCICYGHARAC-PLD---------PATNKSRCECEHNTCGDSCDQC 321
Query: 310 KDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFD-------MTTYLASGGLSGGVCEDC 362
F PWR L C +C+C+ + C++D ++ + + GGVC +C
Sbjct: 322 CPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINC 381
Query: 363 QHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSHSDPA-LGSVAG 421
NT G +C+ C F+R + + P C PC CDP G+++ +CV A G G
Sbjct: 382 TQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLN-EVCVKDEKHARRGLAPG 440
Query: 422 QCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYV 481
C CK G CD+C + G C+ C+C+ LGS C G C+C V
Sbjct: 441 SCHCKTGFGGVSCDRCARGYTGYP-----DCKACNCSGLGSKNEDPC---FGPCICKENV 492
Query: 482 TGAHCEECTVGYWGL-GNHLHGCSPCDCDIGGAYSNVC 518
G C C G++ L ++ GC C C SN C
Sbjct: 493 EGGDCSRCKSGFFNLQEDNWKGCDECFC---SGVSNRC 527
Score = 166 bits (420), Expect = 2e-40
Identities = 94/272 (34%), Positives = 129/272 (47%), Gaps = 27/272 (9%)
Query: 769 CKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDL-GHHGCHPCHCHPQGSKDT 827
C+C+ GS C GQC+C+ V G+ CD+C G++ L GC PC+C+ GSK
Sbjct: 918 CRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKSF 977
Query: 828 VCDQVTGQCPCHGEVSGRRCDRCLAGYFGFP--SCHPCPCNRFAELCDPETGSCFNCGGF 885
C++ +GQC C V+G++CDRC GYF F C C C+ CDP+TG C C
Sbjct: 978 DCEE-SGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGNNCDPKTGRCI-CPPN 1035
Query: 886 TTGRNCERCIDGYYGNPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYT 945
T G C +C +G+ S C+ C C S+ C N CNC ++
Sbjct: 1036 TIGEKCSKCAPNTWGH-SITTGCKACNC----STVGSLDFQCNVNTGQ----CNCHPKFS 1086
Query: 946 GTQCGECSTGFYGNPRISGAPCQPCAC---NNNIDVTDPE----SCSRVTGECLRCLHNT 998
G +C ECS G + PR C C C + D E SCS TG+C C N
Sbjct: 1087 GAKCTECSRGHWNYPR-----CNLCDCFLPGTDATTCDSETKKCSCSDQTGQC-TCKVNV 1140
Query: 999 QGANCQLCKPGHYGSALNQTCRRCSCHASGVS 1030
+G +C C+PG +G SC+ G +
Sbjct: 1141 EGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTT 1172
Score = 164 bits (415), Expect = 7e-40
Identities = 94/259 (36%), Positives = 119/259 (45%), Gaps = 32/259 (12%)
Query: 937 ICNCLQGYTGTQCGECSTGFYG-NPRISGAPCQPCACNNNIDVTDPESCSRVTGECLRCL 995
+C C GYTG+ C C N I G C+PC C + ESC VTGECL C
Sbjct: 723 VCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGH-----AESCDDVTGECLNCK 777
Query: 996 HNTQGANCQLCKPGHYG---SALNQTCRRCSCHASGVSPMECPPGGGACLC------DPV 1046
+T G C C PG YG ++ C+ C+C P+ P + C +
Sbjct: 778 DHTGGPYCDKCLPGFYGEPTKGTSEDCQPCAC------PLNIPSNNFSPTCHLDRSLGLI 831
Query: 1047 TGACPCLPNVTGLACDRCADGYWN--LVPGRGCQSCDCDPRTSQS--SHCDQLTGQC-PC 1101
CP TG C+RCA+GY+ VPG CQ C C+ S CD L+G C C
Sbjct: 832 CDGCPV--GYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLIC 889
Query: 1102 KLGYGGKRCSECQENYYGD--PPGRCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCD 1159
K G G+ C C + Y+GD C PC CN G+ +C TG C CR V GQRCD
Sbjct: 890 KPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCD 949
Query: 1160 RCARG--HSQEFPTCLQCH 1176
+C G Q C+ C+
Sbjct: 950 KCKAGTFGLQSARGCVPCN 968
Score = 144 bits (364), Expect = 6e-34
Identities = 83/254 (32%), Positives = 117/254 (46%), Gaps = 25/254 (9%)
Query: 295 CVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASGGL 354
C C G +CE C + R + C C C H+ C D+T
Sbjct: 724 CQCPPGYTGSSCESCWPRHR----RVNGTIFGGICEPCQCFGHAESCD-DVT-------- 770
Query: 355 SGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSHSDP 414
G C +C+ +T G +CD+C P FY +P K S+ C PC C + + H D
Sbjct: 771 --GECLNCKDHTGGPYCDKCLPGFYGEPTKGTSED--CQPCACPLNIPSNNFSPTCHLDR 826
Query: 415 ALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFL---TCDVD 471
+LG + C G +C++C ++G + CQPC CN +L F +CD
Sbjct: 827 SLGLICDGC--PVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCND--NLDFSIPGSCDSL 882
Query: 472 TGQCL-CLSYVTGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYSNVCSPKNGQCECRPH 530
+G CL C TG +CE C GY+G C PC C+ GG++S VC + GQCECR +
Sbjct: 883 SGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRAN 942
Query: 531 VTGRSCSEPAPGYF 544
V G+ C + G F
Sbjct: 943 VQGQRCDKCKAGTF 956
Score = 139 bits (349), Expect = 3e-32
Identities = 98/323 (30%), Positives = 135/323 (41%), Gaps = 83/323 (25%)
Query: 274 CRPMQKMRGDVFSPPGM---VHGQC-VCQHNTDGPNCERCKD-FFQDAPWRPAADLQDNA 328
C+P Q FS PG + G C +C+ T G CE C D +F DA +
Sbjct: 862 CQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDA-------VDAKN 914
Query: 329 CRSCSCN---SHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKT 385
C+ C CN S S CH G CE C+ N +GQ CD+C+ +
Sbjct: 915 CQPCRCNAGGSFSEVCHSQT-----------GQCE-CRANVQGQRCDKCKAGTFG----- 957
Query: 386 ISDPYACIPCECDPDGT----------------ISGGIC-------------------VS 410
+ C+PC C+ G+ ++G C S
Sbjct: 958 LQSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECS 1017
Query: 411 HSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDV 470
H G+C+C N G KC +C PN +G S T GC+ C+C+ +GSL F C+V
Sbjct: 1018 HLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITT--GCKACNCSTVGSLDF-QCNV 1074
Query: 471 DTGQCLCLSYVTGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYSNVC---------SPK 521
+TGQC C +GA C EC+ G+W C+ CDC + G + C S +
Sbjct: 1075 NTGQCNCHPKFSGAKCTECSRGHWNYPR----CNLCDCFLPGTDATTCDSETKKCSCSDQ 1130
Query: 522 NGQCECRPHVTGRSCSEPAPGYF 544
GQC C+ +V G C PG F
Sbjct: 1131 TGQCTCKVNVEGIHCDRCRPGKF 1153
Score = 137 bits (345), Expect = 9e-32
Identities = 100/380 (26%), Positives = 144/380 (37%), Gaps = 132/380 (34%)
Query: 265 CFCNGHASECRPMQKMRGDVFSPPGMVHGQCV-CQHNTDGPNCERCKDFFQDAPWRPAAD 323
C C GHA C V G+C+ C+ +T GP C++C F P + ++
Sbjct: 757 CQCFGHAESCDD--------------VTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSE 802
Query: 324 LQDNACRSCSC------NSHSSRCHFDMTT----------------------YLASGGLS 355
C+ C+C N+ S CH D + Y +
Sbjct: 803 ----DCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVP 858
Query: 356 GGVCEDCQHN------------------------TEGQHCDRCRPLFYRDPLKTISDPYA 391
GG C+ CQ N T G++C+ C ++ D + D
Sbjct: 859 GGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAV----DAKN 914
Query: 392 CIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLG 451
C PC C+ G+ S V HS GQC C+ NV+G +CD+CK +GL + G
Sbjct: 915 CQPCRCNAGGSFSE---VCHSQ------TGQCECRANVQGQRCDKCKAGTFGLQSAR--G 963
Query: 452 CQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWG-------------LGN 498
C PC+CN GS F C+ ++GQC C VTG C+ C GY+ LGN
Sbjct: 964 CVPCNCNSFGSKSF-DCE-ESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGN 1021
Query: 499 HLH-------------------------------GCSPCDCDIGGAYSNVCSPKNGQCEC 527
+ GC C+C G+ C+ GQC C
Sbjct: 1022 NCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQCNC 1081
Query: 528 RPHVTGRSCSEPAPGYFFAP 547
P +G C+E + G++ P
Sbjct: 1082 HPKFSGAKCTECSRGHWNYP 1101
Score = 134 bits (337), Expect = 8e-31
Identities = 185/820 (22%), Positives = 316/820 (38%), Gaps = 121/820 (14%)
Query: 994 CLHNTQGANCQLCKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACP-C 1052
C G +C+ C PG Y R P +C G + LCDP T C C
Sbjct: 1382 CPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQC--NGHSSLCDPETSICQNC 1439
Query: 1053 LPNVTGLACDRCADGYWNLVPG--RGCQSCDCDPRTSQSSHCDQLTGQ-------CPCKL 1103
+ G C+RCA GY+ +V G CQ C C +S ++ + C
Sbjct: 1440 QHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACPR 1499
Query: 1104 GYGGKRCSECQENYYG---DPPGRCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDR 1160
GY G+ C C Y G +P G C C+C+ G+ CDP TG C CR G +G++CD
Sbjct: 1500 GYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCDG 1559
Query: 1161 CARGHSQEFPTCLQCHLCFDQWDHTISSLSKAVQGLMRLAANMEDKRETLPVCEADFKDL 1220
C H++E +C C D+ + + L RL + T P+ A +K L
Sbjct: 1560 CKHWHARE---GWECVFCGDECTGLL------LGDLARLEQMVMSINLTGPL-PAPYKML 1609
Query: 1221 RGNVSEIERILKHPVFPS-GKFLKVKDYHDSVRRQIMQLNEQL----KAVYEFQDLKDTI 1275
G + + + LKH + P ++ ++ + ++NE L K + +
Sbjct: 1610 YG-LENMTQELKHLLSPQRAPERLIQLAEGNLNTLVTEMNELLTRATKVTADGEQTGQDA 1668
Query: 1276 ERAKNEADLLLEDLQEEIDLQSSVLNASIADSSENIKKYYHISSSAEKKINETSSTINTS 1335
ER A L E ++E ++ AE +NE + +N +
Sbjct: 1669 ERTNTRAKSLGEFIKE-------------------------LARDAE-AVNEKAIKLNET 1702
Query: 1336 ANTRNDLLTILDTLTSKGNLSLERLKQIKIPDIQILNEKVCGDPGNVPCVPLPCGGALCT 1395
TR++ +LE L++ I+ L K + L AL
Sbjct: 1703 LGTRDEAF----------ERNLEGLQKEIDQMIKELRRKNLETQKEIAEDELVAAEALL- 1751
Query: 1396 GRKGHRKCRGPGCHGSLTLSTNALQKAQEAKSIIRNLDKQVRGLKNQIESISEQAEVSKN 1455
K +K G + + + +K + K+ + + +R ++I + V++
Sbjct: 1752 --KKVKKLFGESRGENEEMEKDLREKLADYKNKVDDAWDLLREATDKIREANRLFAVNQK 1809
Query: 1456 NALQLREKLGNIRNQSDSEEENINLFIKKVKNFLLEENVPPEDIEKVANGVLDIHLPIP- 1514
N L +K + +S + I +K+ + L E N ++I + + V DI +P
Sbjct: 1810 NMTALEKK----KEAVESGKRQIENTLKEGNDILDEANRLADEINSIIDYVEDIQTKLPP 1865
Query: 1515 -SQNLTDEL------VKIQKHMQLCEDYRTDENRLNEEA-------DGAQKLLVKAKAAE 1560
S+ L D++ +K +K + + +LN+ + D A+ + A AA
Sbjct: 1866 MSEELNDKIDDLSQEIKDRKLAEKVSQAESHAAQLNDSSAVLDGILDEAKNISFNATAAF 1925
Query: 1561 KA-ANILLNLDKTLNQLQQAQITQGRANSTIT------------------QLTANITKIK 1601
KA +NI +D+ ++A+ A T ++ K+
Sbjct: 1926 KAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPRGLLKEDAKGCLQKSFRILNEAKKLA 1985
Query: 1602 KNVLQAENQTREMKSELELAKQRSG-----LEDGLSLLQ-------TKLQRHQDHAVNAK 1649
+V + E+ +K+ +E A R+G L D L L KLQ +D A A
Sbjct: 1986 NDVKENEDHLNGLKTRIENADARNGDLLRTLNDTLGKLSAIPNDTAAKLQAVKDKARQAN 2045
Query: 1650 VQAESAQHQAGSLEKEFVELKKQYAILQRKTSTTGLTKETLGKVKQLKDAAEKLAGDTEA 1709
A+ Q L + LKK Y L + T + K K + D A+ + E
Sbjct: 2046 DTAKDVLAQITELHQNLDGLKKNYNKLADSVAKTNAVVKDPSKNKIIAD-ADATVKNLEQ 2104
Query: 1710 KIRRITDLERKIQDLNLSRQAKADQLRILEDQVVAIKNEI 1749
+ R+ D + I++L + + +++ L +Q N I
Sbjct: 2105 EADRLIDKLKPIKELEDNLKKNISEIKELINQARKQANSI 2144
Score = 118 bits (296), Expect = 4e-26
Identities = 74/210 (35%), Positives = 91/210 (43%), Gaps = 22/210 (10%)
Query: 835 QCPCHGEVSGRRCDRCLAGYFGFPS-------------CHPCPCNRFAELCDPETGSCFN 881
+C C SG C+ CL G++ S C PC CN + LCDPET C N
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN 1438
Query: 882 CGGFTTGRNCERCIDGYYGNPSSGQP--CRPCLCPDDPSSNQYFAHSCYQNLWSSDVICN 939
C T G CERC GYYG G P C+ C CP SSN F+ SC
Sbjct: 1439 CQHHTAGDFCERCALGYYG-IVKGLPNDCQQCACPLISSSNN-FSPSCVAEGLDDYRCTA 1496
Query: 940 CLQGYTGTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQ 999
C +GY G C C+ G+ G+P G CQ C C+ + P C VTG C C
Sbjct: 1497 CPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSL--PVPCDPVTGFC-TCRPGAT 1553
Query: 1000 GANCQLCKPGHYGSALNQTCRRCSCHASGV 1029
G C CK H+ + C C +G+
Sbjct: 1554 GRKCDGCK--HWHAREGWECVFCGDECTGL 1581
Score = 106 bits (265), Expect = 2e-22
Identities = 66/216 (30%), Positives = 87/216 (40%), Gaps = 18/216 (8%)
Query: 765 GAVACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHGCHPCHCHPQGS 824
G V C C+ GS C GQC C+P V G+ CDRC+ G ++ GC C C G+
Sbjct: 963 GCVPCNCNSFGSKSFDCEE-SGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGN 1021
Query: 825 KDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGF---PSCHPCPCNRFAEL---CDPETGS 878
CD TG+C C G +C +C +G C C C+ L C+ TG
Sbjct: 1022 N---CDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQ 1078
Query: 879 CFNCGGFTTGRNCERCIDGYYGNPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVI- 937
C NC +G C C G++ P C C C P ++ S + SD
Sbjct: 1079 C-NCHPKFSGAKCTECSRGHWNYPR----CNLCDC-FLPGTDATTCDSETKKCSCSDQTG 1132
Query: 938 -CNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCAC 972
C C G C C G +G + C C C
Sbjct: 1133 QCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCYC 1168
Score = 105 bits (263), Expect = 3e-22
Identities = 69/213 (32%), Positives = 91/213 (42%), Gaps = 22/213 (10%)
Query: 281 RGDVFSPPGMVHGQCVCQHNTDGPNCERCKDFFQDAPWRPAADLQD---NACRSCSCNSH 337
RG +PP + +C C G +CE C F +P C C CN H
Sbjct: 1366 RGTTMTPPADLIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGH 1425
Query: 338 SSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCEC 397
SS C + + +C++CQH+T G C+RC L Y +K + P C C C
Sbjct: 1426 SSLCDPETS-----------ICQNCQHHTAGDFCERC-ALGYYGIVKGL--PNDCQQCAC 1471
Query: 398 DPDGTISGGICVSHSDPALGSVAGQC-LCKENVEGAKCDQCKPNHYGLSATDPLGCQPCD 456
IS S S A G +C C EG C++C P + G CQ C+
Sbjct: 1472 P---LISSSNNFSPSCVAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECE 1528
Query: 457 CNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEEC 489
C+P GSLP + CD TG C C TG C+ C
Sbjct: 1529 CDPYGSLP-VPCDPVTGFCTCRPGATGRKCDGC 1560
Score = 100 bits (250), Expect = 1e-20
Identities = 67/210 (31%), Positives = 86/210 (40%), Gaps = 54/210 (25%)
Query: 994 CLHNTQGANCQLCKPGHY------GSALNQT-CRRCSCHASGVSPMECPP---------- 1036
C HNT G +C C PG + G+ L +T C C+CH EC
Sbjct: 309 CEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAE---ECYYDENVARRNLS 365
Query: 1037 --------GGGACLCDPVTGACPCLPNVTGLACDRCADGYWN---LVPG--RGCQSCDCD 1083
GGG C+ C N G+ C+ C DG++ + P R CQ C CD
Sbjct: 366 LNIRGKYIGGGVCI--------NCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCD 417
Query: 1084 PRTSQSSHCDQ---------LTGQCPCKLGYGGKRCSECQENYYGDPPGRCIPCDCNRAG 1134
P S + C + G C CK G+GG C C Y G P C C+C+ G
Sbjct: 418 PIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPD--CKACNCSGLG 475
Query: 1135 TQKPICDPDTGMCRCREGVSGQRCDRCARG 1164
++ DP G C C+E V G C RC G
Sbjct: 476 SKNE--DPCFGPCICKENVEGGDCSRCKSG 503
Score = 96.3 bits (238), Expect = 2e-19
Identities = 70/248 (28%), Positives = 94/248 (37%), Gaps = 64/248 (25%)
Query: 332 CSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLK--TISDP 389
C C H+ C D T + CE C+HNT G CD+C P F++ P + T
Sbjct: 287 CICYGHARACPLDPATNKSR-------CE-CEHNTCGDSCDQCCPGFHQKPWRAGTFLTK 338
Query: 390 YACIPCECDPDGT---------------------ISGGICVSHSDPALGSVAGQCLCKEN 428
C C C I GG+C++ C +N
Sbjct: 339 TECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCIN--------------CTQN 384
Query: 429 VEGAKCDQCKPNHY---GLSATDPLGCQPCDCNPLGSLPFLTCDVDT---------GQCL 476
G C+ C + G+S P CQPC C+P+GSL + C D G C
Sbjct: 385 TAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEV-CVKDEKHARRGLAPGSCH 443
Query: 477 CLSYVTGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYSNVCSPKNGQCECRPHVTGRSC 536
C + G C+ C GY G + C C+C G S P G C C+ +V G C
Sbjct: 444 CKTGFGGVSCDRCARGYTGYPD----CKACNCS--GLGSKNEDPCFGPCICKENVEGGDC 497
Query: 537 SEPAPGYF 544
S G+F
Sbjct: 498 SRCKSGFF 505
Score = 91.3 bits (225), Expect = 8e-18
Identities = 73/249 (29%), Positives = 94/249 (37%), Gaps = 44/249 (17%)
Query: 863 CPCNRFAELC--DPETG-SCFNCGGFTTGRNCERCIDGYYGNP------SSGQPCRPCLC 913
C C A C DP T S C T G +C++C G++ P + C C C
Sbjct: 287 CICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNC 346
Query: 914 PDDPSSNQYFAHSCYQNLW--------SSDVICNCLQGYTGTQCGECSTGFYGNPRISG- 964
Y + +NL V NC Q G C C+ GF+ +S
Sbjct: 347 HGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPN 406
Query: 965 --APCQPCACN-----NNIDVTDPESCSR--VTGECLRCLHNTQGANCQLCKPGHYGSAL 1015
PCQPC C+ N + V D + R G C C G +C C G+ G
Sbjct: 407 YPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSC-HCKTGFGGVSCDRCARGYTGYP- 464
Query: 1016 NQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCADGYWNLVPG- 1074
C+ C+C G S E DP G C C NV G C RC G++NL
Sbjct: 465 --DCKACNCSGLG-SKNE----------DPCFGPCICKENVEGGDCSRCKSGFFNLQEDN 511
Query: 1075 -RGCQSCDC 1082
+GC C C
Sbjct: 512 WKGCDECFC 520
Score = 87.8 bits (216), Expect = 8e-17
Identities = 58/191 (30%), Positives = 78/191 (40%), Gaps = 29/191 (15%)
Query: 361 DCQHNTEGQHCDRCRPLFYR--------DPLKTISDPYACIPCECDPDGTISGGICVSHS 412
DC G C+ C P FYR P T+ C+PC+C+ ++
Sbjct: 1381 DCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLG---TCVPCQCNGHSSLC-------- 1429
Query: 413 DPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSL----PFLTC 468
DP C+ + G C++C +YG+ P CQ C C + S P
Sbjct: 1430 DPETSICQN---CQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVA 1486
Query: 469 D-VDTGQCL-CLSYVTGAHCEECTVGYWGL-GNHLHGCSPCDCDIGGAYSNVCSPKNGQC 525
+ +D +C C G +CE C GY G GN C C+CD G+ C P G C
Sbjct: 1487 EGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFC 1546
Query: 526 ECRPHVTGRSC 536
CRP TGR C
Sbjct: 1547 TCRPGATGRKC 1557
Score = 86.3 bits (212), Expect = 2e-16
Identities = 64/245 (26%), Positives = 93/245 (37%), Gaps = 45/245 (18%)
Query: 913 CPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGA-----PC 967
CP DP++N+ C C G C +C GF+ P +G C
Sbjct: 296 CPLDPATNKSR--------------CECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTEC 341
Query: 968 QPCACNNNIDVTD-PESCSRVT------------GECLRCLHNTQGANCQLCKPGHY--- 1011
+ C C+ + E+ +R G C+ C NT G NC+ C G +
Sbjct: 342 EACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPK 401
Query: 1012 GSALN--QTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCADGYW 1069
G + N + C+ C C G C G+C C G++CDRCA GY
Sbjct: 402 GVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYT 461
Query: 1070 NLVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSECQENYYG---DPPGRCI 1126
C++C+C S++ D G C CK G CS C+ ++ D C
Sbjct: 462 GYPD---CKACNCSGLGSKNE--DPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCD 516
Query: 1127 PCDCN 1131
C C+
Sbjct: 517 ECFCS 521
Score = 82.0 bits (201), Expect = 5e-15
Identities = 58/179 (32%), Positives = 77/179 (43%), Gaps = 36/179 (20%)
Query: 265 CFCNGHASECRPMQKMRGDVFSPPGMVHGQCVCQHNTDGPNCERCK-DFFQDAPWRPAAD 323
C CNGH+S C P + + CQH+T G CERC ++ P
Sbjct: 1420 CQCNGHSSLCDPETSICQN-------------CQHHTAGDFCERCALGYYGIVKGLP--- 1463
Query: 324 LQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPL 383
N C+ C+C SS +F + + GL C C EGQ+C+RC P + P
Sbjct: 1464 ---NDCQQCACPLISSSNNFSPSC--VAEGLDDYRCTACPRGYEGQYCERCAPGYTGSP- 1517
Query: 384 KTISDPY-ACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNH 441
+P +C CECDP G++ DP V G C C+ G KCD CK H
Sbjct: 1518 ---GNPGGSCQECECDPYGSLP-----VPCDP----VTGFCTCRPGATGRKCDGCKHWH 1564
Score = 80.1 bits (196), Expect = 2e-14
Identities = 52/194 (26%), Positives = 69/194 (35%), Gaps = 37/194 (19%)
Query: 293 GQCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASG 352
GQC CQ G C+RC + + Q+ C +C C+ + C +
Sbjct: 983 GQCWCQPGVTGKKCDRCAHGY--------FNFQEGGCTACECSHLGNNCDPKTGRCICPP 1034
Query: 353 GLSGGVCEDCQHNTEGQ-------------------HCD------RCRPLFYRDPLKTIS 387
G C C NT G C+ C P F S
Sbjct: 1035 NTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECS 1094
Query: 388 DPY----ACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYG 443
+ C C+C GT + + GQC CK NVEG CD+C+P +G
Sbjct: 1095 RGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFG 1154
Query: 444 LSATDPLGCQPCDC 457
L A +PLGC C C
Sbjct: 1155 LDAKNPLGCSSCYC 1168
Score = 75.9 bits (185), Expect = 3e-13
Identities = 46/147 (31%), Positives = 60/147 (40%), Gaps = 19/147 (12%)
Query: 785 GGQC-QCKPLVVGRCCDRCSTGSYDLGH------HGCHPCHCHPQGSKDTVCDQ------ 831
GG C C G C+ C+ G + C PCHC P GS + VC +
Sbjct: 375 GGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHAR 434
Query: 832 ---VTGQCPCHGEVSGRRCDRCLAGYFGFPSCHPCPCNRF-AELCDPETGSCFNCGGFTT 887
G C C G CDRC GY G+P C C C+ ++ DP G C C
Sbjct: 435 RGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLGSKNEDPCFGPCI-CKENVE 493
Query: 888 GRNCERCIDGYYG-NPSSGQPCRPCLC 913
G +C RC G++ + + C C C
Sbjct: 494 GGDCSRCKSGFFNLQEDNWKGCDECFC 520
Score = 72.8 bits (177), Expect = 3e-12
Identities = 48/188 (25%), Positives = 72/188 (38%), Gaps = 50/188 (26%)
Query: 1038 GGACLC---------DPVTGA--CPCLPNVTGLACDRCADGY----WN---LVPGRGCQS 1079
GG C+C DP T C C N G +CD+C G+ W + C++
Sbjct: 284 GGMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEA 343
Query: 1080 CDCDPRTSQSSHCDQLT---------------GQC-PCKLGYGGKRCSECQENYYGDP-- 1121
C+C + + + + + G C C G C C + ++
Sbjct: 344 CNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGV 403
Query: 1122 ----PGRCIPCDCNRAGTQKPICDPDT---------GMCRCREGVSGQRCDRCARGHSQE 1168
P C PC C+ G+ +C D G C C+ G G CDRCARG++
Sbjct: 404 SPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYT-G 462
Query: 1169 FPTCLQCH 1176
+P C C+
Sbjct: 463 YPDCKACN 470
Score = 69.3 bits (168), Expect = 3e-11
Identities = 57/231 (24%), Positives = 83/231 (35%), Gaps = 59/231 (25%)
Query: 787 QCQCKPLVVGRCCDRCSTGSYD--------LGHHGCHPCHCHPQGSKDTVCDQVT----- 833
+C+C+ G CD+C G + L C C+CH + + + V
Sbjct: 306 RCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLS 365
Query: 834 ----------GQC-PCHGEVSGRRCDRCLAGYF-------GFPS-CHPCPCNRFA---EL 871
G C C +G C+ C G+F +P C PC C+ E+
Sbjct: 366 LNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEV 425
Query: 872 CDPET---------GSCFNCGGFTTGRNCERCIDGYYGNPSSGQPCRPCLCPDDPSSNQY 922
C + GSC GF G +C+RC GY G P C+ C C S N+
Sbjct: 426 CVKDEKHARRGLAPGSCHCKTGFG-GVSCDRCARGYTGYPD----CKACNCSGLGSKNE- 479
Query: 923 FAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCACN 973
C+ C C + G C C +GF+ + C C C+
Sbjct: 480 --DPCFGP-------CICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCS 521
Score = 65.5 bits (158), Expect = 4e-10
Identities = 46/150 (30%), Positives = 63/150 (42%), Gaps = 18/150 (12%)
Query: 412 SDPALGSVAGQ---CLCKENVEGAKCDQCKPNHYGLSATDPLG-CQPCDCNPLGSLPFLT 467
S P GS+A C C G+ C+ C P H ++ T G C+PC C +
Sbjct: 710 SYPTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAE----S 765
Query: 468 CDVDTGQCL-CLSYVTGAHCEECTVGYWG--LGNHLHGCSPCDCDI---GGAYSNVCSPK 521
CD TG+CL C + G +C++C G++G C PC C + +S C
Sbjct: 766 CDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLD 825
Query: 522 NGQ---CE-CRPHVTGRSCSEPAPGYFFAP 547
C+ C TG C A GYF P
Sbjct: 826 RSLGLICDGCPVGYTGPRCERCAEGYFGQP 855
Score = 65.1 bits (157), Expect = 6e-10
Identities = 44/147 (29%), Positives = 59/147 (40%), Gaps = 23/147 (15%)
Query: 767 VACKCHPQGSVGSSCSRLGGQCQ-CKPLVVGRCCDRCSTGSYDLGH---HGCHPCHCHPQ 822
V C+C+ S+ C CQ C+ G C+RC+ G Y + + C C C
Sbjct: 1418 VPCQCNGHSSL---CDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLI 1474
Query: 823 GSKDTVCDQVTGQ-------CPCHGEVSGRRCDRCLAGYFGFP-----SCHPCPCNRFAE 870
S + + C G+ C+RC GY G P SC C C+ +
Sbjct: 1475 SSSNNFSPSCVAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGS 1534
Query: 871 L---CDPETGSCFNCGGFTTGRNCERC 894
L CDP TG C C TGR C+ C
Sbjct: 1535 LPVPCDPVTGFC-TCRPGATGRKCDGC 1560
Score = 62.0 bits (149), Expect = 5e-09
Identities = 29/83 (34%), Positives = 40/83 (48%), Gaps = 15/83 (18%)
Query: 1095 LTGQCPCKLGYGGKRCSECQENYY-----------GDPPGRCIPCDCNRAGTQKPICDPD 1143
L +C C LGY G C C +Y G G C+PC CN +CDP+
Sbjct: 1376 LIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCN---GHSSLCDPE 1432
Query: 1144 TGMCR-CREGVSGQRCDRCARGH 1165
T +C+ C+ +G C+RCA G+
Sbjct: 1433 TSICQNCQHHTAGDFCERCALGY 1455
Score = 45.4 bits (106), Expect = 5e-04
Identities = 25/81 (30%), Positives = 37/81 (45%), Gaps = 13/81 (16%)
Query: 474 QCLCLSYVTGAHCEECTVGYWGL---------GNHLHGCSPCDCDIGGAYSNVCSPKNGQ 524
+C C +G CE C G++ L G L C PC C+ +S++C P+
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCN---GHSSLCDPETSI 1435
Query: 525 CE-CRPHVTGRSCSEPAPGYF 544
C+ C+ H G C A GY+
Sbjct: 1436 CQNCQHHTAGDFCERCALGYY 1456
Score = 44.7 bits (104), Expect = 8e-04
Identities = 23/72 (31%), Positives = 32/72 (44%), Gaps = 11/72 (15%)
Query: 293 GQCVCQHNTDGPNCERCKDFF---QDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYL 349
G C+C+ N +G +C RCK F Q+ W+ C C C+ S+RC TY
Sbjct: 484 GPCICKENVEGGDCSRCKSGFFNLQEDNWK--------GCDECFCSGVSNRCQSSYWTYG 535
Query: 350 ASGGLSGGVCED 361
+SG D
Sbjct: 536 KIQDMSGWYLTD 547
Score = 43.9 bits (102), Expect = 0.001
Identities = 30/97 (30%), Positives = 41/97 (42%), Gaps = 15/97 (15%)
Query: 713 PQINSLENF---CSKQDLDEYQLHNCVEIASAMGPQVLPGA-CERLIISMSAKLHD---G 765
P I+S NF C + LD+Y+ C P+ G CER + +
Sbjct: 1472 PLISSSNNFSPSCVAEGLDDYRCTAC--------PRGYEGQYCERCAPGYTGSPGNPGGS 1523
Query: 766 AVACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRC 802
C+C P GS+ C + G C C+P GR CD C
Sbjct: 1524 CQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGC 1560
>gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo
sapiens]
Length = 3122
Score = 262 bits (670), Expect = 2e-69
Identities = 129/344 (37%), Positives = 182/344 (52%), Gaps = 28/344 (8%)
Query: 836 CPCHGEVSGRRCDRC------LAGYFGFPSCHPCPCNRFAELCDPETGSCFNCGGFTTGR 889
C C +G C+ C + G C PC C AE CD TG C NC T G
Sbjct: 724 CQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECLNCKDHTGGP 783
Query: 890 NCERCIDGYYGNPSSG--QPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICN-CLQGYTG 946
C++C+ G+YG P+ G + C+PC CP + SN F+ +C+ + S +IC+ C GYTG
Sbjct: 784 YCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNN-FSPTCHLDR-SLGLICDGCPVGYTG 841
Query: 947 TQCGECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQLC 1006
+C C+ G++G P + G CQPC CN+N+D + P SC ++G CL C T G C+LC
Sbjct: 842 PRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELC 901
Query: 1007 KPGHYGSALN-QTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCA 1065
G++G A++ + C+ C C+A G + +C TG C C NV G CD+C
Sbjct: 902 ADGYFGDAVDAKNCQPCRCNAG---------GSFSEVCHSQTGQCECRANVQGQRCDKCK 952
Query: 1066 DGYWNLVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSECQENYYGDPPGRC 1125
G + L RGC C+C+ S+S C++ +GQC C+ G GK+C C Y+ G C
Sbjct: 953 AGTFGLQSARGCVPCNCNSFGSKSFDCEE-SGQCWCQPGVTGKKCDRCAHGYFNFQEGGC 1011
Query: 1126 IPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDRCAR---GHS 1166
C+C+ G CDP TG C C G++C +CA GHS
Sbjct: 1012 TACECSHLGNN---CDPKTGRCICPPNTIGEKCSKCAPNTWGHS 1052
Score = 224 bits (570), Expect = 8e-58
Identities = 151/487 (31%), Positives = 202/487 (41%), Gaps = 84/487 (17%)
Query: 771 CHPQGSVG--SSCSRLGGQC-QCKPLVVGRCCDRCSTGSYDLGHHG----CHPC------ 817
C P G SC + G+C CK G CD+C G Y G C PC
Sbjct: 754 CEPCQCFGHAESCDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNI 813
Query: 818 -------HCHPQGSKDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFP-----SCHPCPC 865
CH S +CD C +G RC+RC GYFG P SC PC C
Sbjct: 814 PSNNFSPTCHLDRSLGLICD------GCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQC 867
Query: 866 NRFAEL-----CDPETGSCFNCGGFTTGRNCERCIDGYYGNPSSGQPCRPCLCPDDPSSN 920
N + CD +GSC C TTGR CE C DGY+G+ + C+PC C ++
Sbjct: 868 NDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRC----NAG 923
Query: 921 QYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTD 980
F+ C+ S C C G +C +C G +G G C PC CN+
Sbjct: 924 GSFSEVCH----SQTGQCECRANVQGQRCDKCKAGTFGLQSARG--CVPCNCNS---FGS 974
Query: 981 PESCSRVTGECLRCLHNTQGANCQLCKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGA 1040
+G+C C G C C G++ + C C C G +
Sbjct: 975 KSFDCEESGQCW-CQPGVTGKKCDRCAHGYF-NFQEGGCTACECSHLGNN---------- 1022
Query: 1041 CLCDPVTGACPCLPNVTGLACDRCADGYWNLVPGRGCQSCDCDPRTSQSSHCDQLTGQCP 1100
CDP TG C C PN G C +CA W GC++C+C S C+ TGQC
Sbjct: 1023 --CDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQCN 1080
Query: 1101 CKLGYGGKRCSECQENYYGDPPGRCIPCDCNRAGTQKPICDPD---------TGMCRCRE 1151
C + G +C+EC ++ P RC CDC GT CD + TG C C+
Sbjct: 1081 CHPKFSGAKCTECSRGHWNYP--RCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKV 1138
Query: 1152 GVSGQRCDRCARG----HSQEFPTCLQCHLCFDQWDHTISSLSKAVQGLMRLAANMEDKR 1207
V G CDRC G ++ C C+ CF T + S+A +GL+R ++ ++
Sbjct: 1139 NVEGIHCDRCRPGKFGLDAKNPLGCSSCY-CFG----TTTQCSEA-KGLIRTWVTLKAEQ 1192
Query: 1208 ETLPVCE 1214
LP+ +
Sbjct: 1193 TILPLVD 1199
Score = 216 bits (551), Expect = 1e-55
Identities = 147/518 (28%), Positives = 240/518 (46%), Gaps = 68/518 (13%)
Query: 35 LLVGRNTQLMASSTCGLSRAQKYC-ILSYLEGEQ----KCFICDSRFPYDPYDQPNS-HT 88
L + N + ++TCG + YC ++ ++ G+ +C IC+ PN H
Sbjct: 44 LNLASNALITTNATCGEKGPEMYCKLVEHVPGQPVRNPQCRICNQNS-----SNPNQRHP 98
Query: 89 IENVIVSFEPDREKKWWQS---ENGLDH--VSIRLDLEALFRFSHLIL-TFKTFRPAAML 142
I N I D + WWQS +NG+++ V+I LDL+ +F+ +++I+ + RP +
Sbjct: 99 ITNAI-----DGKNTWWQSPSIKNGIEYHYVTITLDLQQVFQIAYVIVKAANSPRPGNWI 153
Query: 143 VERSTDYGHNWKVFKYFA---KDCATSF---PNITSGQAQGVGDIVCDSKYSDIEPSTGG 196
+ERS D +K ++Y A +C T + P +++C S YS I P G
Sbjct: 154 LERSLD-DVEYKPWQYHAVTDTECLTLYNIYPRTGPPSYAKDDEVICTSFYSKIHPLENG 212
Query: 197 EVVLKVLDPSFEIENPYSPYIQDLVTLTNLRINFTKLHTLGDALLGRRQNDSLD------ 250
E+ + +++ ++P SP + + + +R+ F ++ TL L+ D +
Sbjct: 213 EIHISLINGRPSADDP-SPELLEFTSARYIRLRFQRIRTLNADLMMFAHKDPREIDPIVT 271
Query: 251 -KYYYALYEMIVRGSCFCNGHASECRPMQKMRGDVFSPPGMVHGQCVCQHNTDGPNCERC 309
+YYY++ ++ V G C C GHA C P+ P +C C+HNT G +C++C
Sbjct: 272 RRYYYSVKDISVGGMCICYGHARAC-PLD---------PATNKSRCECEHNTCGDSCDQC 321
Query: 310 KDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFD-------MTTYLASGGLSGGVCEDC 362
F PWR L C +C+C+ + C++D ++ + + GGVC +C
Sbjct: 322 CPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINC 381
Query: 363 QHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSHSDPA-LGSVAG 421
NT G +C+ C F+R + + P C PC CDP G+++ +CV A G G
Sbjct: 382 TQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLN-EVCVKDEKHARRGLAPG 440
Query: 422 QCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYV 481
C CK G CD+C + G C+ C+C+ LGS C G C+C V
Sbjct: 441 SCHCKTGFGGVSCDRCARGYTGYP-----DCKACNCSGLGSKNEDPC---FGPCICKENV 492
Query: 482 TGAHCEECTVGYWGL-GNHLHGCSPCDCDIGGAYSNVC 518
G C C G++ L ++ GC C C SN C
Sbjct: 493 EGGDCSRCKSGFFNLQEDNWKGCDECFC---SGVSNRC 527
Score = 166 bits (420), Expect = 2e-40
Identities = 94/272 (34%), Positives = 129/272 (47%), Gaps = 27/272 (9%)
Query: 769 CKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDL-GHHGCHPCHCHPQGSKDT 827
C+C+ GS C GQC+C+ V G+ CD+C G++ L GC PC+C+ GSK
Sbjct: 918 CRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKSF 977
Query: 828 VCDQVTGQCPCHGEVSGRRCDRCLAGYFGFP--SCHPCPCNRFAELCDPETGSCFNCGGF 885
C++ +GQC C V+G++CDRC GYF F C C C+ CDP+TG C C
Sbjct: 978 DCEE-SGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGNNCDPKTGRCI-CPPN 1035
Query: 886 TTGRNCERCIDGYYGNPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYT 945
T G C +C +G+ S C+ C C S+ C N CNC ++
Sbjct: 1036 TIGEKCSKCAPNTWGH-SITTGCKACNC----STVGSLDFQCNVNTGQ----CNCHPKFS 1086
Query: 946 GTQCGECSTGFYGNPRISGAPCQPCAC---NNNIDVTDPE----SCSRVTGECLRCLHNT 998
G +C ECS G + PR C C C + D E SCS TG+C C N
Sbjct: 1087 GAKCTECSRGHWNYPR-----CNLCDCFLPGTDATTCDSETKKCSCSDQTGQC-TCKVNV 1140
Query: 999 QGANCQLCKPGHYGSALNQTCRRCSCHASGVS 1030
+G +C C+PG +G SC+ G +
Sbjct: 1141 EGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTT 1172
Score = 164 bits (415), Expect = 7e-40
Identities = 94/259 (36%), Positives = 119/259 (45%), Gaps = 32/259 (12%)
Query: 937 ICNCLQGYTGTQCGECSTGFYG-NPRISGAPCQPCACNNNIDVTDPESCSRVTGECLRCL 995
+C C GYTG+ C C N I G C+PC C + ESC VTGECL C
Sbjct: 723 VCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGH-----AESCDDVTGECLNCK 777
Query: 996 HNTQGANCQLCKPGHYG---SALNQTCRRCSCHASGVSPMECPPGGGACLC------DPV 1046
+T G C C PG YG ++ C+ C+C P+ P + C +
Sbjct: 778 DHTGGPYCDKCLPGFYGEPTKGTSEDCQPCAC------PLNIPSNNFSPTCHLDRSLGLI 831
Query: 1047 TGACPCLPNVTGLACDRCADGYWN--LVPGRGCQSCDCDPRTSQS--SHCDQLTGQC-PC 1101
CP TG C+RCA+GY+ VPG CQ C C+ S CD L+G C C
Sbjct: 832 CDGCPV--GYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLIC 889
Query: 1102 KLGYGGKRCSECQENYYGD--PPGRCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCD 1159
K G G+ C C + Y+GD C PC CN G+ +C TG C CR V GQRCD
Sbjct: 890 KPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCD 949
Query: 1160 RCARG--HSQEFPTCLQCH 1176
+C G Q C+ C+
Sbjct: 950 KCKAGTFGLQSARGCVPCN 968
Score = 144 bits (364), Expect = 6e-34
Identities = 83/254 (32%), Positives = 117/254 (46%), Gaps = 25/254 (9%)
Query: 295 CVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASGGL 354
C C G +CE C + R + C C C H+ C D+T
Sbjct: 724 CQCPPGYTGSSCESCWPRHR----RVNGTIFGGICEPCQCFGHAESCD-DVT-------- 770
Query: 355 SGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSHSDP 414
G C +C+ +T G +CD+C P FY +P K S+ C PC C + + H D
Sbjct: 771 --GECLNCKDHTGGPYCDKCLPGFYGEPTKGTSED--CQPCACPLNIPSNNFSPTCHLDR 826
Query: 415 ALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFL---TCDVD 471
+LG + C G +C++C ++G + CQPC CN +L F +CD
Sbjct: 827 SLGLICDGC--PVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCND--NLDFSIPGSCDSL 882
Query: 472 TGQCL-CLSYVTGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYSNVCSPKNGQCECRPH 530
+G CL C TG +CE C GY+G C PC C+ GG++S VC + GQCECR +
Sbjct: 883 SGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRAN 942
Query: 531 VTGRSCSEPAPGYF 544
V G+ C + G F
Sbjct: 943 VQGQRCDKCKAGTF 956
Score = 139 bits (349), Expect = 3e-32
Identities = 98/323 (30%), Positives = 135/323 (41%), Gaps = 83/323 (25%)
Query: 274 CRPMQKMRGDVFSPPGM---VHGQC-VCQHNTDGPNCERCKD-FFQDAPWRPAADLQDNA 328
C+P Q FS PG + G C +C+ T G CE C D +F DA +
Sbjct: 862 CQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDA-------VDAKN 914
Query: 329 CRSCSCN---SHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKT 385
C+ C CN S S CH G CE C+ N +GQ CD+C+ +
Sbjct: 915 CQPCRCNAGGSFSEVCHSQT-----------GQCE-CRANVQGQRCDKCKAGTFG----- 957
Query: 386 ISDPYACIPCECDPDGT----------------ISGGIC-------------------VS 410
+ C+PC C+ G+ ++G C S
Sbjct: 958 LQSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECS 1017
Query: 411 HSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDV 470
H G+C+C N G KC +C PN +G S T GC+ C+C+ +GSL F C+V
Sbjct: 1018 HLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITT--GCKACNCSTVGSLDF-QCNV 1074
Query: 471 DTGQCLCLSYVTGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYSNVC---------SPK 521
+TGQC C +GA C EC+ G+W C+ CDC + G + C S +
Sbjct: 1075 NTGQCNCHPKFSGAKCTECSRGHWNYPR----CNLCDCFLPGTDATTCDSETKKCSCSDQ 1130
Query: 522 NGQCECRPHVTGRSCSEPAPGYF 544
GQC C+ +V G C PG F
Sbjct: 1131 TGQCTCKVNVEGIHCDRCRPGKF 1153
Score = 137 bits (345), Expect = 9e-32
Identities = 100/380 (26%), Positives = 144/380 (37%), Gaps = 132/380 (34%)
Query: 265 CFCNGHASECRPMQKMRGDVFSPPGMVHGQCV-CQHNTDGPNCERCKDFFQDAPWRPAAD 323
C C GHA C V G+C+ C+ +T GP C++C F P + ++
Sbjct: 757 CQCFGHAESCDD--------------VTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSE 802
Query: 324 LQDNACRSCSC------NSHSSRCHFDMTT----------------------YLASGGLS 355
C+ C+C N+ S CH D + Y +
Sbjct: 803 ----DCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVP 858
Query: 356 GGVCEDCQHN------------------------TEGQHCDRCRPLFYRDPLKTISDPYA 391
GG C+ CQ N T G++C+ C ++ D + D
Sbjct: 859 GGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAV----DAKN 914
Query: 392 CIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLG 451
C PC C+ G+ S V HS GQC C+ NV+G +CD+CK +GL + G
Sbjct: 915 CQPCRCNAGGSFSE---VCHSQ------TGQCECRANVQGQRCDKCKAGTFGLQSAR--G 963
Query: 452 CQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWG-------------LGN 498
C PC+CN GS F C+ ++GQC C VTG C+ C GY+ LGN
Sbjct: 964 CVPCNCNSFGSKSF-DCE-ESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGN 1021
Query: 499 HLH-------------------------------GCSPCDCDIGGAYSNVCSPKNGQCEC 527
+ GC C+C G+ C+ GQC C
Sbjct: 1022 NCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQCNC 1081
Query: 528 RPHVTGRSCSEPAPGYFFAP 547
P +G C+E + G++ P
Sbjct: 1082 HPKFSGAKCTECSRGHWNYP 1101
Score = 134 bits (337), Expect = 8e-31
Identities = 185/820 (22%), Positives = 316/820 (38%), Gaps = 121/820 (14%)
Query: 994 CLHNTQGANCQLCKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACP-C 1052
C G +C+ C PG Y R P +C G + LCDP T C C
Sbjct: 1382 CPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQC--NGHSSLCDPETSICQNC 1439
Query: 1053 LPNVTGLACDRCADGYWNLVPG--RGCQSCDCDPRTSQSSHCDQLTGQ-------CPCKL 1103
+ G C+RCA GY+ +V G CQ C C +S ++ + C
Sbjct: 1440 QHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACPR 1499
Query: 1104 GYGGKRCSECQENYYG---DPPGRCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDR 1160
GY G+ C C Y G +P G C C+C+ G+ CDP TG C CR G +G++CD
Sbjct: 1500 GYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCDG 1559
Query: 1161 CARGHSQEFPTCLQCHLCFDQWDHTISSLSKAVQGLMRLAANMEDKRETLPVCEADFKDL 1220
C H++E +C C D+ + + L RL + T P+ A +K L
Sbjct: 1560 CKHWHARE---GWECVFCGDECTGLL------LGDLARLEQMVMSINLTGPL-PAPYKML 1609
Query: 1221 RGNVSEIERILKHPVFPS-GKFLKVKDYHDSVRRQIMQLNEQL----KAVYEFQDLKDTI 1275
G + + + LKH + P ++ ++ + ++NE L K + +
Sbjct: 1610 YG-LENMTQELKHLLSPQRAPERLIQLAEGNLNTLVTEMNELLTRATKVTADGEQTGQDA 1668
Query: 1276 ERAKNEADLLLEDLQEEIDLQSSVLNASIADSSENIKKYYHISSSAEKKINETSSTINTS 1335
ER A L E ++E ++ AE +NE + +N +
Sbjct: 1669 ERTNTRAKSLGEFIKE-------------------------LARDAE-AVNEKAIKLNET 1702
Query: 1336 ANTRNDLLTILDTLTSKGNLSLERLKQIKIPDIQILNEKVCGDPGNVPCVPLPCGGALCT 1395
TR++ +LE L++ I+ L K + L AL
Sbjct: 1703 LGTRDEAF----------ERNLEGLQKEIDQMIKELRRKNLETQKEIAEDELVAAEALL- 1751
Query: 1396 GRKGHRKCRGPGCHGSLTLSTNALQKAQEAKSIIRNLDKQVRGLKNQIESISEQAEVSKN 1455
K +K G + + + +K + K+ + + +R ++I + V++
Sbjct: 1752 --KKVKKLFGESRGENEEMEKDLREKLADYKNKVDDAWDLLREATDKIREANRLFAVNQK 1809
Query: 1456 NALQLREKLGNIRNQSDSEEENINLFIKKVKNFLLEENVPPEDIEKVANGVLDIHLPIP- 1514
N L +K + +S + I +K+ + L E N ++I + + V DI +P
Sbjct: 1810 NMTALEKK----KEAVESGKRQIENTLKEGNDILDEANRLADEINSIIDYVEDIQTKLPP 1865
Query: 1515 -SQNLTDEL------VKIQKHMQLCEDYRTDENRLNEEA-------DGAQKLLVKAKAAE 1560
S+ L D++ +K +K + + +LN+ + D A+ + A AA
Sbjct: 1866 MSEELNDKIDDLSQEIKDRKLAEKVSQAESHAAQLNDSSAVLDGILDEAKNISFNATAAF 1925
Query: 1561 KA-ANILLNLDKTLNQLQQAQITQGRANSTIT------------------QLTANITKIK 1601
KA +NI +D+ ++A+ A T ++ K+
Sbjct: 1926 KAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPRGLLKEDAKGCLQKSFRILNEAKKLA 1985
Query: 1602 KNVLQAENQTREMKSELELAKQRSG-----LEDGLSLLQ-------TKLQRHQDHAVNAK 1649
+V + E+ +K+ +E A R+G L D L L KLQ +D A A
Sbjct: 1986 NDVKENEDHLNGLKTRIENADARNGDLLRTLNDTLGKLSAIPNDTAAKLQAVKDKARQAN 2045
Query: 1650 VQAESAQHQAGSLEKEFVELKKQYAILQRKTSTTGLTKETLGKVKQLKDAAEKLAGDTEA 1709
A+ Q L + LKK Y L + T + K K + D A+ + E
Sbjct: 2046 DTAKDVLAQITELHQNLDGLKKNYNKLADSVAKTNAVVKDPSKNKIIAD-ADATVKNLEQ 2104
Query: 1710 KIRRITDLERKIQDLNLSRQAKADQLRILEDQVVAIKNEI 1749
+ R+ D + I++L + + +++ L +Q N I
Sbjct: 2105 EADRLIDKLKPIKELEDNLKKNISEIKELINQARKQANSI 2144
Score = 118 bits (296), Expect = 4e-26
Identities = 74/210 (35%), Positives = 91/210 (43%), Gaps = 22/210 (10%)
Query: 835 QCPCHGEVSGRRCDRCLAGYFGFPS-------------CHPCPCNRFAELCDPETGSCFN 881
+C C SG C+ CL G++ S C PC CN + LCDPET C N
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN 1438
Query: 882 CGGFTTGRNCERCIDGYYGNPSSGQP--CRPCLCPDDPSSNQYFAHSCYQNLWSSDVICN 939
C T G CERC GYYG G P C+ C CP SSN F+ SC
Sbjct: 1439 CQHHTAGDFCERCALGYYG-IVKGLPNDCQQCACPLISSSNN-FSPSCVAEGLDDYRCTA 1496
Query: 940 CLQGYTGTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQ 999
C +GY G C C+ G+ G+P G CQ C C+ + P C VTG C C
Sbjct: 1497 CPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSL--PVPCDPVTGFC-TCRPGAT 1553
Query: 1000 GANCQLCKPGHYGSALNQTCRRCSCHASGV 1029
G C CK H+ + C C +G+
Sbjct: 1554 GRKCDGCK--HWHAREGWECVFCGDECTGL 1581
Score = 106 bits (265), Expect = 2e-22
Identities = 66/216 (30%), Positives = 87/216 (40%), Gaps = 18/216 (8%)
Query: 765 GAVACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHGCHPCHCHPQGS 824
G V C C+ GS C GQC C+P V G+ CDRC+ G ++ GC C C G+
Sbjct: 963 GCVPCNCNSFGSKSFDCEE-SGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGN 1021
Query: 825 KDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGF---PSCHPCPCNRFAEL---CDPETGS 878
CD TG+C C G +C +C +G C C C+ L C+ TG
Sbjct: 1022 N---CDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQ 1078
Query: 879 CFNCGGFTTGRNCERCIDGYYGNPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVI- 937
C NC +G C C G++ P C C C P ++ S + SD
Sbjct: 1079 C-NCHPKFSGAKCTECSRGHWNYPR----CNLCDC-FLPGTDATTCDSETKKCSCSDQTG 1132
Query: 938 -CNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCAC 972
C C G C C G +G + C C C
Sbjct: 1133 QCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCYC 1168
Score = 105 bits (263), Expect = 3e-22
Identities = 69/213 (32%), Positives = 91/213 (42%), Gaps = 22/213 (10%)
Query: 281 RGDVFSPPGMVHGQCVCQHNTDGPNCERCKDFFQDAPWRPAADLQD---NACRSCSCNSH 337
RG +PP + +C C G +CE C F +P C C CN H
Sbjct: 1366 RGTTMTPPADLIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGH 1425
Query: 338 SSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCEC 397
SS C + + +C++CQH+T G C+RC L Y +K + P C C C
Sbjct: 1426 SSLCDPETS-----------ICQNCQHHTAGDFCERC-ALGYYGIVKGL--PNDCQQCAC 1471
Query: 398 DPDGTISGGICVSHSDPALGSVAGQC-LCKENVEGAKCDQCKPNHYGLSATDPLGCQPCD 456
IS S S A G +C C EG C++C P + G CQ C+
Sbjct: 1472 P---LISSSNNFSPSCVAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECE 1528
Query: 457 CNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEEC 489
C+P GSLP + CD TG C C TG C+ C
Sbjct: 1529 CDPYGSLP-VPCDPVTGFCTCRPGATGRKCDGC 1560
Score = 100 bits (250), Expect = 1e-20
Identities = 67/210 (31%), Positives = 86/210 (40%), Gaps = 54/210 (25%)
Query: 994 CLHNTQGANCQLCKPGHY------GSALNQT-CRRCSCHASGVSPMECPP---------- 1036
C HNT G +C C PG + G+ L +T C C+CH EC
Sbjct: 309 CEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAE---ECYYDENVARRNLS 365
Query: 1037 --------GGGACLCDPVTGACPCLPNVTGLACDRCADGYWN---LVPG--RGCQSCDCD 1083
GGG C+ C N G+ C+ C DG++ + P R CQ C CD
Sbjct: 366 LNIRGKYIGGGVCI--------NCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCD 417
Query: 1084 PRTSQSSHCDQ---------LTGQCPCKLGYGGKRCSECQENYYGDPPGRCIPCDCNRAG 1134
P S + C + G C CK G+GG C C Y G P C C+C+ G
Sbjct: 418 PIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPD--CKACNCSGLG 475
Query: 1135 TQKPICDPDTGMCRCREGVSGQRCDRCARG 1164
++ DP G C C+E V G C RC G
Sbjct: 476 SKNE--DPCFGPCICKENVEGGDCSRCKSG 503
Score = 96.3 bits (238), Expect = 2e-19
Identities = 70/248 (28%), Positives = 94/248 (37%), Gaps = 64/248 (25%)
Query: 332 CSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLK--TISDP 389
C C H+ C D T + CE C+HNT G CD+C P F++ P + T
Sbjct: 287 CICYGHARACPLDPATNKSR-------CE-CEHNTCGDSCDQCCPGFHQKPWRAGTFLTK 338
Query: 390 YACIPCECDPDGT---------------------ISGGICVSHSDPALGSVAGQCLCKEN 428
C C C I GG+C++ C +N
Sbjct: 339 TECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCIN--------------CTQN 384
Query: 429 VEGAKCDQCKPNHY---GLSATDPLGCQPCDCNPLGSLPFLTCDVDT---------GQCL 476
G C+ C + G+S P CQPC C+P+GSL + C D G C
Sbjct: 385 TAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEV-CVKDEKHARRGLAPGSCH 443
Query: 477 CLSYVTGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYSNVCSPKNGQCECRPHVTGRSC 536
C + G C+ C GY G + C C+C G S P G C C+ +V G C
Sbjct: 444 CKTGFGGVSCDRCARGYTGYPD----CKACNCS--GLGSKNEDPCFGPCICKENVEGGDC 497
Query: 537 SEPAPGYF 544
S G+F
Sbjct: 498 SRCKSGFF 505
Score = 91.3 bits (225), Expect = 8e-18
Identities = 73/249 (29%), Positives = 94/249 (37%), Gaps = 44/249 (17%)
Query: 863 CPCNRFAELC--DPETG-SCFNCGGFTTGRNCERCIDGYYGNP------SSGQPCRPCLC 913
C C A C DP T S C T G +C++C G++ P + C C C
Sbjct: 287 CICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNC 346
Query: 914 PDDPSSNQYFAHSCYQNLW--------SSDVICNCLQGYTGTQCGECSTGFYGNPRISG- 964
Y + +NL V NC Q G C C+ GF+ +S
Sbjct: 347 HGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPN 406
Query: 965 --APCQPCACN-----NNIDVTDPESCSR--VTGECLRCLHNTQGANCQLCKPGHYGSAL 1015
PCQPC C+ N + V D + R G C C G +C C G+ G
Sbjct: 407 YPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSC-HCKTGFGGVSCDRCARGYTGYP- 464
Query: 1016 NQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCADGYWNLVPG- 1074
C+ C+C G S E DP G C C NV G C RC G++NL
Sbjct: 465 --DCKACNCSGLG-SKNE----------DPCFGPCICKENVEGGDCSRCKSGFFNLQEDN 511
Query: 1075 -RGCQSCDC 1082
+GC C C
Sbjct: 512 WKGCDECFC 520
Score = 87.8 bits (216), Expect = 8e-17
Identities = 58/191 (30%), Positives = 78/191 (40%), Gaps = 29/191 (15%)
Query: 361 DCQHNTEGQHCDRCRPLFYR--------DPLKTISDPYACIPCECDPDGTISGGICVSHS 412
DC G C+ C P FYR P T+ C+PC+C+ ++
Sbjct: 1381 DCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLG---TCVPCQCNGHSSLC-------- 1429
Query: 413 DPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSL----PFLTC 468
DP C+ + G C++C +YG+ P CQ C C + S P
Sbjct: 1430 DPETSICQN---CQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVA 1486
Query: 469 D-VDTGQCL-CLSYVTGAHCEECTVGYWGL-GNHLHGCSPCDCDIGGAYSNVCSPKNGQC 525
+ +D +C C G +CE C GY G GN C C+CD G+ C P G C
Sbjct: 1487 EGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFC 1546
Query: 526 ECRPHVTGRSC 536
CRP TGR C
Sbjct: 1547 TCRPGATGRKC 1557
Score = 86.3 bits (212), Expect = 2e-16
Identities = 64/245 (26%), Positives = 93/245 (37%), Gaps = 45/245 (18%)
Query: 913 CPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGA-----PC 967
CP DP++N+ C C G C +C GF+ P +G C
Sbjct: 296 CPLDPATNKSR--------------CECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTEC 341
Query: 968 QPCACNNNIDVTD-PESCSRVT------------GECLRCLHNTQGANCQLCKPGHY--- 1011
+ C C+ + E+ +R G C+ C NT G NC+ C G +
Sbjct: 342 EACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPK 401
Query: 1012 GSALN--QTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCADGYW 1069
G + N + C+ C C G C G+C C G++CDRCA GY
Sbjct: 402 GVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYT 461
Query: 1070 NLVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSECQENYYG---DPPGRCI 1126
C++C+C S++ D G C CK G CS C+ ++ D C
Sbjct: 462 GYPD---CKACNCSGLGSKNE--DPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCD 516
Query: 1127 PCDCN 1131
C C+
Sbjct: 517 ECFCS 521
Score = 82.0 bits (201), Expect = 5e-15
Identities = 58/179 (32%), Positives = 77/179 (43%), Gaps = 36/179 (20%)
Query: 265 CFCNGHASECRPMQKMRGDVFSPPGMVHGQCVCQHNTDGPNCERCK-DFFQDAPWRPAAD 323
C CNGH+S C P + + CQH+T G CERC ++ P
Sbjct: 1420 CQCNGHSSLCDPETSICQN-------------CQHHTAGDFCERCALGYYGIVKGLP--- 1463
Query: 324 LQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPL 383
N C+ C+C SS +F + + GL C C EGQ+C+RC P + P
Sbjct: 1464 ---NDCQQCACPLISSSNNFSPSC--VAEGLDDYRCTACPRGYEGQYCERCAPGYTGSP- 1517
Query: 384 KTISDPY-ACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNH 441
+P +C CECDP G++ DP V G C C+ G KCD CK H
Sbjct: 1518 ---GNPGGSCQECECDPYGSLP-----VPCDP----VTGFCTCRPGATGRKCDGCKHWH 1564
Score = 80.1 bits (196), Expect = 2e-14
Identities = 52/194 (26%), Positives = 69/194 (35%), Gaps = 37/194 (19%)
Query: 293 GQCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASG 352
GQC CQ G C+RC + + Q+ C +C C+ + C +
Sbjct: 983 GQCWCQPGVTGKKCDRCAHGY--------FNFQEGGCTACECSHLGNNCDPKTGRCICPP 1034
Query: 353 GLSGGVCEDCQHNTEGQ-------------------HCD------RCRPLFYRDPLKTIS 387
G C C NT G C+ C P F S
Sbjct: 1035 NTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECS 1094
Query: 388 DPY----ACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYG 443
+ C C+C GT + + GQC CK NVEG CD+C+P +G
Sbjct: 1095 RGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFG 1154
Query: 444 LSATDPLGCQPCDC 457
L A +PLGC C C
Sbjct: 1155 LDAKNPLGCSSCYC 1168
Score = 75.9 bits (185), Expect = 3e-13
Identities = 46/147 (31%), Positives = 60/147 (40%), Gaps = 19/147 (12%)
Query: 785 GGQC-QCKPLVVGRCCDRCSTGSYDLGH------HGCHPCHCHPQGSKDTVCDQ------ 831
GG C C G C+ C+ G + C PCHC P GS + VC +
Sbjct: 375 GGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHAR 434
Query: 832 ---VTGQCPCHGEVSGRRCDRCLAGYFGFPSCHPCPCNRF-AELCDPETGSCFNCGGFTT 887
G C C G CDRC GY G+P C C C+ ++ DP G C C
Sbjct: 435 RGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLGSKNEDPCFGPCI-CKENVE 493
Query: 888 GRNCERCIDGYYG-NPSSGQPCRPCLC 913
G +C RC G++ + + C C C
Sbjct: 494 GGDCSRCKSGFFNLQEDNWKGCDECFC 520
Score = 72.8 bits (177), Expect = 3e-12
Identities = 48/188 (25%), Positives = 72/188 (38%), Gaps = 50/188 (26%)
Query: 1038 GGACLC---------DPVTGA--CPCLPNVTGLACDRCADGY----WN---LVPGRGCQS 1079
GG C+C DP T C C N G +CD+C G+ W + C++
Sbjct: 284 GGMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEA 343
Query: 1080 CDCDPRTSQSSHCDQLT---------------GQC-PCKLGYGGKRCSECQENYYGDP-- 1121
C+C + + + + + G C C G C C + ++
Sbjct: 344 CNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGV 403
Query: 1122 ----PGRCIPCDCNRAGTQKPICDPDT---------GMCRCREGVSGQRCDRCARGHSQE 1168
P C PC C+ G+ +C D G C C+ G G CDRCARG++
Sbjct: 404 SPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYT-G 462
Query: 1169 FPTCLQCH 1176
+P C C+
Sbjct: 463 YPDCKACN 470
Score = 69.3 bits (168), Expect = 3e-11
Identities = 57/231 (24%), Positives = 83/231 (35%), Gaps = 59/231 (25%)
Query: 787 QCQCKPLVVGRCCDRCSTGSYD--------LGHHGCHPCHCHPQGSKDTVCDQVT----- 833
+C+C+ G CD+C G + L C C+CH + + + V
Sbjct: 306 RCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLS 365
Query: 834 ----------GQC-PCHGEVSGRRCDRCLAGYF-------GFPS-CHPCPCNRFA---EL 871
G C C +G C+ C G+F +P C PC C+ E+
Sbjct: 366 LNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEV 425
Query: 872 CDPET---------GSCFNCGGFTTGRNCERCIDGYYGNPSSGQPCRPCLCPDDPSSNQY 922
C + GSC GF G +C+RC GY G P C+ C C S N+
Sbjct: 426 CVKDEKHARRGLAPGSCHCKTGFG-GVSCDRCARGYTGYPD----CKACNCSGLGSKNE- 479
Query: 923 FAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCACN 973
C+ C C + G C C +GF+ + C C C+
Sbjct: 480 --DPCFGP-------CICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCS 521
Score = 65.5 bits (158), Expect = 4e-10
Identities = 46/150 (30%), Positives = 63/150 (42%), Gaps = 18/150 (12%)
Query: 412 SDPALGSVAGQ---CLCKENVEGAKCDQCKPNHYGLSATDPLG-CQPCDCNPLGSLPFLT 467
S P GS+A C C G+ C+ C P H ++ T G C+PC C +
Sbjct: 710 SYPTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAE----S 765
Query: 468 CDVDTGQCL-CLSYVTGAHCEECTVGYWG--LGNHLHGCSPCDCDI---GGAYSNVCSPK 521
CD TG+CL C + G +C++C G++G C PC C + +S C
Sbjct: 766 CDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLD 825
Query: 522 NGQ---CE-CRPHVTGRSCSEPAPGYFFAP 547
C+ C TG C A GYF P
Sbjct: 826 RSLGLICDGCPVGYTGPRCERCAEGYFGQP 855
Score = 65.1 bits (157), Expect = 6e-10
Identities = 44/147 (29%), Positives = 59/147 (40%), Gaps = 23/147 (15%)
Query: 767 VACKCHPQGSVGSSCSRLGGQCQ-CKPLVVGRCCDRCSTGSYDLGH---HGCHPCHCHPQ 822
V C+C+ S+ C CQ C+ G C+RC+ G Y + + C C C
Sbjct: 1418 VPCQCNGHSSL---CDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLI 1474
Query: 823 GSKDTVCDQVTGQ-------CPCHGEVSGRRCDRCLAGYFGFP-----SCHPCPCNRFAE 870
S + + C G+ C+RC GY G P SC C C+ +
Sbjct: 1475 SSSNNFSPSCVAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGS 1534
Query: 871 L---CDPETGSCFNCGGFTTGRNCERC 894
L CDP TG C C TGR C+ C
Sbjct: 1535 LPVPCDPVTGFC-TCRPGATGRKCDGC 1560
Score = 62.0 bits (149), Expect = 5e-09
Identities = 29/83 (34%), Positives = 40/83 (48%), Gaps = 15/83 (18%)
Query: 1095 LTGQCPCKLGYGGKRCSECQENYY-----------GDPPGRCIPCDCNRAGTQKPICDPD 1143
L +C C LGY G C C +Y G G C+PC CN +CDP+
Sbjct: 1376 LIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCN---GHSSLCDPE 1432
Query: 1144 TGMCR-CREGVSGQRCDRCARGH 1165
T +C+ C+ +G C+RCA G+
Sbjct: 1433 TSICQNCQHHTAGDFCERCALGY 1455
Score = 45.4 bits (106), Expect = 5e-04
Identities = 25/81 (30%), Positives = 37/81 (45%), Gaps = 13/81 (16%)
Query: 474 QCLCLSYVTGAHCEECTVGYWGL---------GNHLHGCSPCDCDIGGAYSNVCSPKNGQ 524
+C C +G CE C G++ L G L C PC C+ +S++C P+
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCN---GHSSLCDPETSI 1435
Query: 525 CE-CRPHVTGRSCSEPAPGYF 544
C+ C+ H G C A GY+
Sbjct: 1436 CQNCQHHTAGDFCERCALGYY 1456
Score = 44.7 bits (104), Expect = 8e-04
Identities = 23/72 (31%), Positives = 32/72 (44%), Gaps = 11/72 (15%)
Query: 293 GQCVCQHNTDGPNCERCKDFF---QDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYL 349
G C+C+ N +G +C RCK F Q+ W+ C C C+ S+RC TY
Sbjct: 484 GPCICKENVEGGDCSRCKSGFFNLQEDNWK--------GCDECFCSGVSNRCQSSYWTYG 535
Query: 350 ASGGLSGGVCED 361
+SG D
Sbjct: 536 KIQDMSGWYLTD 547
Score = 43.9 bits (102), Expect = 0.001
Identities = 30/97 (30%), Positives = 41/97 (42%), Gaps = 15/97 (15%)
Query: 713 PQINSLENF---CSKQDLDEYQLHNCVEIASAMGPQVLPGA-CERLIISMSAKLHD---G 765
P I+S NF C + LD+Y+ C P+ G CER + +
Sbjct: 1472 PLISSSNNFSPSCVAEGLDDYRCTAC--------PRGYEGQYCERCAPGYTGSPGNPGGS 1523
Query: 766 AVACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRC 802
C+C P GS+ C + G C C+P GR CD C
Sbjct: 1524 CQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGC 1560
>gi|219842266 usherin isoform B [Homo sapiens]
Length = 5202
Score = 251 bits (642), Expect = 3e-66
Identities = 137/439 (31%), Positives = 221/439 (50%), Gaps = 46/439 (10%)
Query: 114 VSIRLDLE-ALFRFSHLILTFKTFRPAAMLVERSTDYGHNWKVFKYFAKDCATSFPNITS 172
V+I +DLE ++ ++I+ F + +P + ++R + +W+ ++YFA++C +F +
Sbjct: 369 VTISVDLENGQYQVFYIIIQFFSPQPTEIRIQRKKENSLDWEDWQYFARNCG-AFGMKNN 427
Query: 173 GQAQGVGDIVCDSKYSDIEPSTGGEVVLKVLDPSFEIENPYS-----PYIQDLVTLTNLR 227
G + + C + S+ P + G V +L P Y+ P +Q+ V T +R
Sbjct: 428 GDLEKPDSVNC-LQLSNFTPYSRGNVTFSILTPGPNYRPGYNNFYNTPSLQEFVKATQIR 486
Query: 228 INFTKLHTLGDALLGRRQNDSLDKYYYALYEMIVRGSCFCNGHASECRPMQKMRGDVFSP 287
+F + + + R YYA+ E+ + G C C+GHA C D S
Sbjct: 487 FHFHGQYYTTETAVNLRHR------YYAVDEITISGRCQCHGHADNC--------DTTSQ 532
Query: 288 PGMVHGQCVCQHN--TDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDM 345
P +C+C T+G +C+RC + D P+R + C+ C CNSHS CH+++
Sbjct: 533 PY----RCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNI 588
Query: 346 TT------YLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDP 399
+ + GG GVC+DC+HNT G++C+ C+ F+R S C PC+CD
Sbjct: 589 SVDPFPFEHFRGGG---GVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDT 645
Query: 400 DGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNP 459
GT +G I + GQC CK +V G +C+QC+ Y L DP GC PC+CN
Sbjct: 646 VGTRNGSILCD-------QIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNT 698
Query: 460 LGSLP-FLTCDVDTGQCLCLSYVTGAHCEECTVGYWGLGNHLH-GCSPCDCDIGGAYSNV 517
G++ +TC ++GQC C + V G C+ C G+ L + GC PC C++ G+ +
Sbjct: 699 SGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKF 758
Query: 518 CSPKNGQCECRPHVTGRSC 536
C+P +GQCEC+ G C
Sbjct: 759 CNPHSGQCECKKEAKGLQC 777
Score = 248 bits (634), Expect = 3e-65
Identities = 135/415 (32%), Positives = 196/415 (47%), Gaps = 42/415 (10%)
Query: 769 CKCHPQGSVGSS--CSRLGGQCQCKPLVVGRCCDRCSTGSYDLGH---HGCHPCHCHPQG 823
C C G+ S C ++GGQC CK V GR C++C G Y+L GC PC+C+ G
Sbjct: 641 CDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSG 700
Query: 824 SKD--TVCDQVTGQCPCHGEVSGRRCDRCLAGY-----FGFPSCHPCPCNRFAEL---CD 873
+ D C Q +GQC C V G RCD C G+ F C PC CN + C+
Sbjct: 701 TVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCN 760
Query: 874 PETGSCFNCGGFTTGRNCERCIDGYYGNPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWS 933
P +G C C G C+ C + +YG + C+ C C S ++
Sbjct: 761 PHSGQC-ECKKEAKGLQCDTCRENFYGLDVTN--CKACDCDTAGSLPGTVCNAKTGQ--- 814
Query: 934 SDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLR 993
C C G QC +C G + + + C PC C+ + C++ TG+C
Sbjct: 815 ----CICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQC-P 869
Query: 994 CLHNTQGANCQLCKPGHYGSALN--QTCRRCSCHASGVSPMECPPGGGACLCDPVTGACP 1051
C G C C+P Y ++ Q C+ C C + G P +CDP++G C
Sbjct: 870 CKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLP--------GTICDPISGQCL 921
Query: 1052 CLPNVTGLACDRCADGYWNLVPGR--GCQSCDCDPRTSQSSHCDQLTGQCPCK-LGYGGK 1108
C+PN G C++C G++ + PG GC C C + + C+ LTGQC C+ G+
Sbjct: 922 CVPNRQGRRCNQCQPGFY-ISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQ 980
Query: 1109 RCSECQENYYGDPP--GRCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDRC 1161
RC +C+++Y+G P GRC PC+C+ +G C TG C C++ V+G +CD C
Sbjct: 981 RCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDAC 1035
Score = 213 bits (541), Expect = 2e-54
Identities = 130/422 (30%), Positives = 189/422 (44%), Gaps = 49/422 (11%)
Query: 785 GGQCQ-CKPLVVGRCCDRCS------TGSYDLGHHGCHPCHCHPQGSKD--TVCDQVTGQ 835
GG C C+ GR C+ C G+ C PC C G+++ +CDQ+ GQ
Sbjct: 602 GGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQ 661
Query: 836 CPCHGEVSGRRCDRCLAGYFGFPS-----CHPCPCNRFAEL-----CDPETGSCFNCGGF 885
C C VSGR+C++C G++ C PC CN + C +G C C
Sbjct: 662 CNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQC-KCKAN 720
Query: 886 TTGRNCERCIDGY-YGNPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGY 944
G C+ C G+ + + C PC C S N++ Q C C +
Sbjct: 721 VIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQ--------CECKKEA 772
Query: 945 TGTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQ 1004
G QC C FYG + C+ C C+ + C+ TG+C+ C N +G C
Sbjct: 773 KGLQCDTCRENFYG---LDVTNCKACDCDTAGSLPGTV-CNAKTGQCI-CKPNVEGRQCN 827
Query: 1005 LCKPGHYGSALNQT--CRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACD 1062
C G++ N + C C+C +G G+ LC+ TG CPC VTGL C+
Sbjct: 828 KCLEGNFYLRQNNSFLCLPCNCDKTGTI-------NGSLLCNKSTGQCPCKLGVTGLRCN 880
Query: 1063 RCADGYWNLVPG--RGCQSCDCDPR-TSQSSHCDQLTGQCPCKLGYGGKRCSECQENYYG 1119
+C +NL + CQ C+CD T + CD ++GQC C G+RC++CQ +Y
Sbjct: 881 QCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYI 940
Query: 1120 DPPGR--CIPCDCNRAGTQKPICDPDTGMCRCREG-VSGQRCDRCARGHSQEFPTCLQCH 1176
P C+PC C+ G IC+ TG C C++ ++GQRCD+C + P +C
Sbjct: 941 SPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQ 1000
Query: 1177 LC 1178
C
Sbjct: 1001 PC 1002
Score = 206 bits (524), Expect = 2e-52
Identities = 119/365 (32%), Positives = 169/365 (46%), Gaps = 33/365 (9%)
Query: 764 DGAVACKCHPQGSVGS--SCSRLGGQCQCKPLVVGRCCDRCSTGSYDL---GHHGCHPCH 818
DG C C+ G+V +C + GQC+CK V+G CD C+ G L GC PC
Sbjct: 689 DGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQ 748
Query: 819 CHPQGSKDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGF--PSCHPCPCNRFAEL----C 872
C+ GS + C+ +GQC C E G +CD C ++G +C C C+ L C
Sbjct: 749 CNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVC 808
Query: 873 DPETGSCFNCGGFTTGRNCERCIDG-YYGNPSSGQPCRPCLCPDDPSSNQYFAHSCYQNL 931
+ +TG C C GR C +C++G +Y ++ C PC C + N +
Sbjct: 809 NAKTGQCI-CKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCN----- 862
Query: 932 WSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGEC 991
S C C G TG +C +C Y + CQ C C +++ C ++G+C
Sbjct: 863 -KSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCEC-DSLGTLPGTICDPISGQC 920
Query: 992 LRCLHNTQGANCQLCKPGHYGSALNQT-CRRCSCHASGVSPMECPPGGGACLCDPVTGAC 1050
L C+ N QG C C+PG Y S N T C CSCH +G +C+ +TG C
Sbjct: 921 L-CVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNH---------ICNSLTGQC 970
Query: 1051 PCL-PNVTGLACDRCADGYWNLVPGRG-CQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGK 1108
C ++ G CD+C D Y+ P G CQ C+C + + C +TGQC CK G
Sbjct: 971 VCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGS 1030
Query: 1109 RCSEC 1113
+C C
Sbjct: 1031 KCDAC 1035
Score = 188 bits (477), Expect = 5e-47
Identities = 128/427 (29%), Positives = 172/427 (40%), Gaps = 86/427 (20%)
Query: 817 CHCHPQGSK-DTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFP----------SCHPCPC 865
C CH DT C G CDRCL Y P +C PC C
Sbjct: 518 CQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQC 577
Query: 866 NRFAELC------DPET--------GSCFNCGGFTTGRNCERCIDGYY----GNPSSGQP 907
N ++ C DP G C +C TTGRNCE C D ++ +PS+
Sbjct: 578 NSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDV 637
Query: 908 CRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPC 967
C+PC C D + + C Q CNC + +G QC +C GFY + C
Sbjct: 638 CKPCDC--DTVGTRNGSILCDQIGGQ----CNCKRHVSGRQCNQCQNGFYNLQELDPDGC 691
Query: 968 QPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQLCKPGH-YGSALNQT-CRRCSCH 1025
PC CN + V +C + +G+C +C N G C C G + + N C C C+
Sbjct: 692 SPCNCNTSGTVDGDITCHQNSGQC-KCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCN 750
Query: 1026 ASGVSPMECPPGGGAC----------------------------------------LCDP 1045
G C P G C +C+
Sbjct: 751 LHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNA 810
Query: 1046 VTGACPCLPNVTGLACDRCADGYWNLVPGRG--CQSCDCDPR--TSQSSHCDQLTGQCPC 1101
TG C C PNV G C++C +G + L C C+CD + S C++ TGQCPC
Sbjct: 811 KTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPC 870
Query: 1102 KLGYGGKRCSECQENYYG---DPPGRCIPCDCNRAGTQK-PICDPDTGMCRCREGVSGQR 1157
KLG G RC++C+ + Y D C C+C+ GT ICDP +G C C G+R
Sbjct: 871 KLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRR 930
Query: 1158 CDRCARG 1164
C++C G
Sbjct: 931 CNQCQPG 937
Score = 187 bits (475), Expect = 8e-47
Identities = 119/386 (30%), Positives = 171/386 (44%), Gaps = 73/386 (18%)
Query: 832 VTGQCPCHGE--------------------VSGRRCDRCLAGYFGFP----------SCH 861
++G+C CHG G CDRCL Y P +C
Sbjct: 514 ISGRCQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCK 573
Query: 862 PCPCNRFAELC------DP--------ETGSCFNCGGFTTGRNCERCIDGYY----GNPS 903
PC CN ++ C DP G C +C TTGRNCE C D ++ +PS
Sbjct: 574 PCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPS 633
Query: 904 SGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRIS 963
+ C+PC C D + + C Q CNC + +G QC +C GFY +
Sbjct: 634 AIDVCKPCDC--DTVGTRNGSILCDQ----IGGQCNCKRHVSGRQCNQCQNGFYNLQELD 687
Query: 964 GAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQLCKPG-HYGSALNQT-CRR 1021
C PC CN + V +C + +G+C +C N G C C G + + N C
Sbjct: 688 PDGCSPCNCNTSGTVDGDITCHQNSGQC-KCKANVIGLRCDHCNFGFKFLRSFNDVGCEP 746
Query: 1022 CSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCADGYWNLVPGRGCQSCD 1081
C C+ G C+P +G C C GL CD C + ++ L C++CD
Sbjct: 747 CQCNLHGSVNK---------FCNPHSGQCECKKEAKGLQCDTCRENFYGL-DVTNCKACD 796
Query: 1082 CDPRTS-QSSHCDQLTGQCPCKLGYGGKRCSECQE-NYY--GDPPGRCIPCDCNRAGT-- 1135
CD S + C+ TGQC CK G++C++C E N+Y + C+PC+C++ GT
Sbjct: 797 CDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTIN 856
Query: 1136 QKPICDPDTGMCRCREGVSGQRCDRC 1161
+C+ TG C C+ GV+G RC++C
Sbjct: 857 GSLLCNKSTGQCPCKLGVTGLRCNQC 882
Score = 160 bits (406), Expect = 8e-39
Identities = 102/343 (29%), Positives = 147/343 (42%), Gaps = 65/343 (18%)
Query: 244 RQNDSLDKYYYALYEMIVRGSCFCNGHASECRPMQKMRGDVFSPPGMVHGQCVCQHNTDG 303
RQ + +Y L E+ G CN C + GD+ GQC C+ N G
Sbjct: 671 RQCNQCQNGFYNLQELDPDGCSPCN-----CNTSGTVDGDITCHQNS--GQCKCKANVIG 723
Query: 304 PNCERCKDFFQDAPWRPAADLQDNACRSCSCN----------SHSSRCH----------- 342
C+ C F+ D C C CN HS +C
Sbjct: 724 LRCDHCNFGFKFL-----RSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCD 778
Query: 343 --------FDMTTYLA-----SGGLSGGVCED------CQHNTEGQHCDRC-RPLFYRDP 382
D+T A +G L G VC C+ N EG+ C++C FY
Sbjct: 779 TCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQ 838
Query: 383 LKTISDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHY 442
++ + C+PC CD GTI+G + + S GQC CK V G +C+QC+P+ Y
Sbjct: 839 ----NNSFLCLPCNCDKTGTINGSLLCNKS-------TGQCPCKLGVTGLRCNQCEPHRY 887
Query: 443 GLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGLGNHLHG 502
L+ + CQ C+C+ LG+LP CD +GQCLC+ G C +C G++ + G
Sbjct: 888 NLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATG 947
Query: 503 CSPCDCDIGGAYSNVCSPKNGQCECR-PHVTGRSCSEPAPGYF 544
C PC C GA +++C+ GQC C+ + G+ C + YF
Sbjct: 948 CLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYF 990
Score = 147 bits (370), Expect = 1e-34
Identities = 98/313 (31%), Positives = 142/313 (45%), Gaps = 70/313 (22%)
Query: 266 FCNGHASECRPMQKMRG-------------DVF-----------SPPGMV----HGQCVC 297
FCN H+ +C ++ +G DV S PG V GQC+C
Sbjct: 758 FCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQCIC 817
Query: 298 QHNTDGPNCERCKD--FFQDAPWRPAADLQDNA--CRSCSCNSHSSRCHFDMTTYLASGG 353
+ N +G C +C + F+ Q+N+ C C+C+ T +G
Sbjct: 818 KPNVEGRQCNKCLEGNFYLR---------QNNSFLCLPCNCDK----------TGTINGS 858
Query: 354 L----SGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICV 409
L S G C C+ G C++C P Y TI + C CECD GT+ G IC
Sbjct: 859 LLCNKSTGQCP-CKLGVTGLRCNQCEPHRYN---LTIDNFQHCQMCECDSLGTLPGTIC- 913
Query: 410 SHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCD 469
DP ++GQCLC N +G +C+QC+P Y +S + GC PC C+ G++ + C+
Sbjct: 914 ---DP----ISGQCLCVPNRQGRRCNQCQPGFY-ISPGNATGCLPCSCHTTGAVNHI-CN 964
Query: 470 VDTGQCLCL-SYVTGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYSNVCSPKNGQCECR 528
TGQC+C + + G C++C Y+G C PC+C + GA + C GQC C+
Sbjct: 965 SLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFCK 1024
Query: 529 PHVTGRSCSEPAP 541
VTG C P
Sbjct: 1025 QFVTGSKCDACVP 1037
Score = 108 bits (269), Expect = 6e-23
Identities = 54/138 (39%), Positives = 74/138 (53%), Gaps = 12/138 (8%)
Query: 769 CKCHPQGSV-GSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHH--GCHPCHCHPQGSK 825
C+C G++ G+ C + GQC C P GR C++C G Y + GC PC CH G+
Sbjct: 900 CECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAV 959
Query: 826 DTVCDQVTGQCPCH-GEVSGRRCDRCLAGYFGFPS----CHPCPCN---RFAELCDPETG 877
+ +C+ +TGQC C ++G+RCD+C YFGF C PC C+ E C TG
Sbjct: 960 NHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTG 1019
Query: 878 SCFNCGGFTTGRNCERCI 895
CF C F TG C+ C+
Sbjct: 1020 QCF-CKQFVTGSKCDACV 1036
Score = 78.6 bits (192), Expect = 5e-14
Identities = 52/181 (28%), Positives = 77/181 (42%), Gaps = 32/181 (17%)
Query: 273 ECRPMQKMRGDVFSPPGMVHGQCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSC 332
EC + + G + P + GQC+C N G C +C+ F +P C C
Sbjct: 901 ECDSLGTLPGTICDP---ISGQCLCVPNRQGRRCNQCQPGFYISPGNATG------CLPC 951
Query: 333 SCNSHSSRCHFDMTTYLASGGLSGG-VCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYA 391
SC++ + H L+G VC+D + GQ CD+C+ ++ +T
Sbjct: 952 SCHTTGAVNHI-------CNSLTGQCVCQDA--SIAGQRCDQCKDHYFGFDPQT----GR 998
Query: 392 CIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLG 451
C PC C G ++ V GQC CK+ V G+KCD C P+ L + LG
Sbjct: 999 CQPCNCHLSGALN---------ETCHLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLG 1049
Query: 452 C 452
C
Sbjct: 1050 C 1050
Score = 78.6 bits (192), Expect = 5e-14
Identities = 35/90 (38%), Positives = 49/90 (54%), Gaps = 3/90 (3%)
Query: 765 GAVACKCHPQGSVGSSCSRLGGQCQCKPL-VVGRCCDRCSTG--SYDLGHHGCHPCHCHP 821
G + C CH G+V C+ L GQC C+ + G+ CD+C +D C PC+CH
Sbjct: 947 GCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHL 1006
Query: 822 QGSKDTVCDQVTGQCPCHGEVSGRRCDRCL 851
G+ + C VTGQC C V+G +CD C+
Sbjct: 1007 SGALNETCHLVTGQCFCKQFVTGSKCDACV 1036
Score = 68.2 bits (165), Expect = 7e-11
Identities = 52/169 (30%), Positives = 71/169 (42%), Gaps = 26/169 (15%)
Query: 402 TISGGI-CVSHSDPA-LGSVAGQCLCKEN--VEGAKCDQCKP--NHYGLSATDPL---GC 452
TISG C H+D S +CLC + EG CD+C P N D + C
Sbjct: 513 TISGRCQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNC 572
Query: 453 QPCDCNPLGSLPFLTCDVDT----------GQCL-CLSYVTGAHCEECTVGYWGL----G 497
+PC CN VD G C C TG +CE C ++
Sbjct: 573 KPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADP 632
Query: 498 NHLHGCSPCDCDIGGAYSN--VCSPKNGQCECRPHVTGRSCSEPAPGYF 544
+ + C PCDCD G + +C GQC C+ HV+GR C++ G++
Sbjct: 633 SAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFY 681
Score = 32.0 bits (71), Expect = 5.5
Identities = 57/251 (22%), Positives = 87/251 (34%), Gaps = 37/251 (14%)
Query: 807 YDLGHHGCHPCHCHP---QGSKDTVCDQVTGQCP---CHGEVSGRRCDRCLAGYFGFPSC 860
YDL +PC Q D +C V Q P C C G P
Sbjct: 3143 YDLLWKTWYPCAKTQKLVQDQSDELCKAVRCQKPESICGHICYSSEAKVCCNGVLYNPKP 3202
Query: 861 -HPCPCNRFAELCDPETGSCFNCGG-FTTGRNCERCIDGYYGNPSSGQPCRPCLCPDDPS 918
H C ++ TG C CGG + +C GYY G+ C CPD+
Sbjct: 3203 GHRCCEEKYIPFVLNSTGVC--CGGRIQEAQPNHQCCSGYYARILPGEVC----CPDEQH 3256
Query: 919 S--NQYFAHSCYQNL---WSSDVIC---NCLQGYTGTQCG--------ECSTGFYGNPRI 962
+ + SC + S + IC G+ CG EC G G
Sbjct: 3257 NRVSVGIGDSCCGRMPYSTSGNQICCAGRLHDGHGQKCCGRQIVSNDLECCGGEEG-VVY 3315
Query: 963 SGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQLCKPGHYGSALNQTCRRC 1022
+ P C + ++++D CS +GE + + C+ + L ++C
Sbjct: 3316 NRLPGMFCCGQDYVNMSDTICCSASSGESKAHIKKNDPVPVKCCE-----TELIPKSQKC 3370
Query: 1023 SCHASGVSPME 1033
C+ G +P++
Sbjct: 3371 -CNGVGYNPLK 3380
>gi|219842259 usherin isoform A [Homo sapiens]
Length = 1546
Score = 251 bits (642), Expect = 3e-66
Identities = 137/439 (31%), Positives = 221/439 (50%), Gaps = 46/439 (10%)
Query: 114 VSIRLDLE-ALFRFSHLILTFKTFRPAAMLVERSTDYGHNWKVFKYFAKDCATSFPNITS 172
V+I +DLE ++ ++I+ F + +P + ++R + +W+ ++YFA++C +F +
Sbjct: 369 VTISVDLENGQYQVFYIIIQFFSPQPTEIRIQRKKENSLDWEDWQYFARNCG-AFGMKNN 427
Query: 173 GQAQGVGDIVCDSKYSDIEPSTGGEVVLKVLDPSFEIENPYS-----PYIQDLVTLTNLR 227
G + + C + S+ P + G V +L P Y+ P +Q+ V T +R
Sbjct: 428 GDLEKPDSVNC-LQLSNFTPYSRGNVTFSILTPGPNYRPGYNNFYNTPSLQEFVKATQIR 486
Query: 228 INFTKLHTLGDALLGRRQNDSLDKYYYALYEMIVRGSCFCNGHASECRPMQKMRGDVFSP 287
+F + + + R YYA+ E+ + G C C+GHA C D S
Sbjct: 487 FHFHGQYYTTETAVNLRHR------YYAVDEITISGRCQCHGHADNC--------DTTSQ 532
Query: 288 PGMVHGQCVCQHN--TDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDM 345
P +C+C T+G +C+RC + D P+R + C+ C CNSHS CH+++
Sbjct: 533 PY----RCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNI 588
Query: 346 TT------YLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDP 399
+ + GG GVC+DC+HNT G++C+ C+ F+R S C PC+CD
Sbjct: 589 SVDPFPFEHFRGGG---GVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDT 645
Query: 400 DGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNP 459
GT +G I + GQC CK +V G +C+QC+ Y L DP GC PC+CN
Sbjct: 646 VGTRNGSILCD-------QIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNT 698
Query: 460 LGSLP-FLTCDVDTGQCLCLSYVTGAHCEECTVGYWGLGNHLH-GCSPCDCDIGGAYSNV 517
G++ +TC ++GQC C + V G C+ C G+ L + GC PC C++ G+ +
Sbjct: 699 SGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKF 758
Query: 518 CSPKNGQCECRPHVTGRSC 536
C+P +GQCEC+ G C
Sbjct: 759 CNPHSGQCECKKEAKGLQC 777
Score = 248 bits (634), Expect = 3e-65
Identities = 135/415 (32%), Positives = 196/415 (47%), Gaps = 42/415 (10%)
Query: 769 CKCHPQGSVGSS--CSRLGGQCQCKPLVVGRCCDRCSTGSYDLGH---HGCHPCHCHPQG 823
C C G+ S C ++GGQC CK V GR C++C G Y+L GC PC+C+ G
Sbjct: 641 CDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSG 700
Query: 824 SKD--TVCDQVTGQCPCHGEVSGRRCDRCLAGY-----FGFPSCHPCPCNRFAEL---CD 873
+ D C Q +GQC C V G RCD C G+ F C PC CN + C+
Sbjct: 701 TVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCN 760
Query: 874 PETGSCFNCGGFTTGRNCERCIDGYYGNPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWS 933
P +G C C G C+ C + +YG + C+ C C S ++
Sbjct: 761 PHSGQC-ECKKEAKGLQCDTCRENFYGLDVTN--CKACDCDTAGSLPGTVCNAKTGQ--- 814
Query: 934 SDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLR 993
C C G QC +C G + + + C PC C+ + C++ TG+C
Sbjct: 815 ----CICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQC-P 869
Query: 994 CLHNTQGANCQLCKPGHYGSALN--QTCRRCSCHASGVSPMECPPGGGACLCDPVTGACP 1051
C G C C+P Y ++ Q C+ C C + G P +CDP++G C
Sbjct: 870 CKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLP--------GTICDPISGQCL 921
Query: 1052 CLPNVTGLACDRCADGYWNLVPGR--GCQSCDCDPRTSQSSHCDQLTGQCPCK-LGYGGK 1108
C+PN G C++C G++ + PG GC C C + + C+ LTGQC C+ G+
Sbjct: 922 CVPNRQGRRCNQCQPGFY-ISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQ 980
Query: 1109 RCSECQENYYGDPP--GRCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDRC 1161
RC +C+++Y+G P GRC PC+C+ +G C TG C C++ V+G +CD C
Sbjct: 981 RCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDAC 1035
Score = 213 bits (541), Expect = 2e-54
Identities = 130/422 (30%), Positives = 189/422 (44%), Gaps = 49/422 (11%)
Query: 785 GGQCQ-CKPLVVGRCCDRCS------TGSYDLGHHGCHPCHCHPQGSKD--TVCDQVTGQ 835
GG C C+ GR C+ C G+ C PC C G+++ +CDQ+ GQ
Sbjct: 602 GGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQ 661
Query: 836 CPCHGEVSGRRCDRCLAGYFGFPS-----CHPCPCNRFAEL-----CDPETGSCFNCGGF 885
C C VSGR+C++C G++ C PC CN + C +G C C
Sbjct: 662 CNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQC-KCKAN 720
Query: 886 TTGRNCERCIDGY-YGNPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGY 944
G C+ C G+ + + C PC C S N++ Q C C +
Sbjct: 721 VIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQ--------CECKKEA 772
Query: 945 TGTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQ 1004
G QC C FYG + C+ C C+ + C+ TG+C+ C N +G C
Sbjct: 773 KGLQCDTCRENFYG---LDVTNCKACDCDTAGSLPGTV-CNAKTGQCI-CKPNVEGRQCN 827
Query: 1005 LCKPGHYGSALNQT--CRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACD 1062
C G++ N + C C+C +G G+ LC+ TG CPC VTGL C+
Sbjct: 828 KCLEGNFYLRQNNSFLCLPCNCDKTGTI-------NGSLLCNKSTGQCPCKLGVTGLRCN 880
Query: 1063 RCADGYWNLVPG--RGCQSCDCDPR-TSQSSHCDQLTGQCPCKLGYGGKRCSECQENYYG 1119
+C +NL + CQ C+CD T + CD ++GQC C G+RC++CQ +Y
Sbjct: 881 QCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYI 940
Query: 1120 DPPGR--CIPCDCNRAGTQKPICDPDTGMCRCREG-VSGQRCDRCARGHSQEFPTCLQCH 1176
P C+PC C+ G IC+ TG C C++ ++GQRCD+C + P +C
Sbjct: 941 SPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQ 1000
Query: 1177 LC 1178
C
Sbjct: 1001 PC 1002
Score = 206 bits (524), Expect = 2e-52
Identities = 119/365 (32%), Positives = 169/365 (46%), Gaps = 33/365 (9%)
Query: 764 DGAVACKCHPQGSVGS--SCSRLGGQCQCKPLVVGRCCDRCSTGSYDL---GHHGCHPCH 818
DG C C+ G+V +C + GQC+CK V+G CD C+ G L GC PC
Sbjct: 689 DGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQ 748
Query: 819 CHPQGSKDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGF--PSCHPCPCNRFAEL----C 872
C+ GS + C+ +GQC C E G +CD C ++G +C C C+ L C
Sbjct: 749 CNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVC 808
Query: 873 DPETGSCFNCGGFTTGRNCERCIDG-YYGNPSSGQPCRPCLCPDDPSSNQYFAHSCYQNL 931
+ +TG C C GR C +C++G +Y ++ C PC C + N +
Sbjct: 809 NAKTGQCI-CKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCN----- 862
Query: 932 WSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGEC 991
S C C G TG +C +C Y + CQ C C +++ C ++G+C
Sbjct: 863 -KSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCEC-DSLGTLPGTICDPISGQC 920
Query: 992 LRCLHNTQGANCQLCKPGHYGSALNQT-CRRCSCHASGVSPMECPPGGGACLCDPVTGAC 1050
L C+ N QG C C+PG Y S N T C CSCH +G +C+ +TG C
Sbjct: 921 L-CVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNH---------ICNSLTGQC 970
Query: 1051 PCL-PNVTGLACDRCADGYWNLVPGRG-CQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGK 1108
C ++ G CD+C D Y+ P G CQ C+C + + C +TGQC CK G
Sbjct: 971 VCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGS 1030
Query: 1109 RCSEC 1113
+C C
Sbjct: 1031 KCDAC 1035
Score = 188 bits (477), Expect = 5e-47
Identities = 128/427 (29%), Positives = 172/427 (40%), Gaps = 86/427 (20%)
Query: 817 CHCHPQGSK-DTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFP----------SCHPCPC 865
C CH DT C G CDRCL Y P +C PC C
Sbjct: 518 CQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQC 577
Query: 866 NRFAELC------DPET--------GSCFNCGGFTTGRNCERCIDGYY----GNPSSGQP 907
N ++ C DP G C +C TTGRNCE C D ++ +PS+
Sbjct: 578 NSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDV 637
Query: 908 CRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPC 967
C+PC C D + + C Q CNC + +G QC +C GFY + C
Sbjct: 638 CKPCDC--DTVGTRNGSILCDQIGGQ----CNCKRHVSGRQCNQCQNGFYNLQELDPDGC 691
Query: 968 QPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQLCKPGH-YGSALNQT-CRRCSCH 1025
PC CN + V +C + +G+C +C N G C C G + + N C C C+
Sbjct: 692 SPCNCNTSGTVDGDITCHQNSGQC-KCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCN 750
Query: 1026 ASGVSPMECPPGGGAC----------------------------------------LCDP 1045
G C P G C +C+
Sbjct: 751 LHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNA 810
Query: 1046 VTGACPCLPNVTGLACDRCADGYWNLVPGRG--CQSCDCDPR--TSQSSHCDQLTGQCPC 1101
TG C C PNV G C++C +G + L C C+CD + S C++ TGQCPC
Sbjct: 811 KTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPC 870
Query: 1102 KLGYGGKRCSECQENYYG---DPPGRCIPCDCNRAGTQK-PICDPDTGMCRCREGVSGQR 1157
KLG G RC++C+ + Y D C C+C+ GT ICDP +G C C G+R
Sbjct: 871 KLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRR 930
Query: 1158 CDRCARG 1164
C++C G
Sbjct: 931 CNQCQPG 937
Score = 187 bits (475), Expect = 8e-47
Identities = 119/386 (30%), Positives = 171/386 (44%), Gaps = 73/386 (18%)
Query: 832 VTGQCPCHGE--------------------VSGRRCDRCLAGYFGFP----------SCH 861
++G+C CHG G CDRCL Y P +C
Sbjct: 514 ISGRCQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCK 573
Query: 862 PCPCNRFAELC------DP--------ETGSCFNCGGFTTGRNCERCIDGYY----GNPS 903
PC CN ++ C DP G C +C TTGRNCE C D ++ +PS
Sbjct: 574 PCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPS 633
Query: 904 SGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRIS 963
+ C+PC C D + + C Q CNC + +G QC +C GFY +
Sbjct: 634 AIDVCKPCDC--DTVGTRNGSILCDQ----IGGQCNCKRHVSGRQCNQCQNGFYNLQELD 687
Query: 964 GAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQLCKPG-HYGSALNQT-CRR 1021
C PC CN + V +C + +G+C +C N G C C G + + N C
Sbjct: 688 PDGCSPCNCNTSGTVDGDITCHQNSGQC-KCKANVIGLRCDHCNFGFKFLRSFNDVGCEP 746
Query: 1022 CSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCADGYWNLVPGRGCQSCD 1081
C C+ G C+P +G C C GL CD C + ++ L C++CD
Sbjct: 747 CQCNLHGSVNK---------FCNPHSGQCECKKEAKGLQCDTCRENFYGL-DVTNCKACD 796
Query: 1082 CDPRTS-QSSHCDQLTGQCPCKLGYGGKRCSECQE-NYY--GDPPGRCIPCDCNRAGT-- 1135
CD S + C+ TGQC CK G++C++C E N+Y + C+PC+C++ GT
Sbjct: 797 CDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTIN 856
Query: 1136 QKPICDPDTGMCRCREGVSGQRCDRC 1161
+C+ TG C C+ GV+G RC++C
Sbjct: 857 GSLLCNKSTGQCPCKLGVTGLRCNQC 882
Score = 160 bits (406), Expect = 8e-39
Identities = 102/343 (29%), Positives = 147/343 (42%), Gaps = 65/343 (18%)
Query: 244 RQNDSLDKYYYALYEMIVRGSCFCNGHASECRPMQKMRGDVFSPPGMVHGQCVCQHNTDG 303
RQ + +Y L E+ G CN C + GD+ GQC C+ N G
Sbjct: 671 RQCNQCQNGFYNLQELDPDGCSPCN-----CNTSGTVDGDITCHQNS--GQCKCKANVIG 723
Query: 304 PNCERCKDFFQDAPWRPAADLQDNACRSCSCN----------SHSSRCH----------- 342
C+ C F+ D C C CN HS +C
Sbjct: 724 LRCDHCNFGFKFL-----RSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCD 778
Query: 343 --------FDMTTYLA-----SGGLSGGVCED------CQHNTEGQHCDRC-RPLFYRDP 382
D+T A +G L G VC C+ N EG+ C++C FY
Sbjct: 779 TCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQ 838
Query: 383 LKTISDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHY 442
++ + C+PC CD GTI+G + + S GQC CK V G +C+QC+P+ Y
Sbjct: 839 ----NNSFLCLPCNCDKTGTINGSLLCNKS-------TGQCPCKLGVTGLRCNQCEPHRY 887
Query: 443 GLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGLGNHLHG 502
L+ + CQ C+C+ LG+LP CD +GQCLC+ G C +C G++ + G
Sbjct: 888 NLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATG 947
Query: 503 CSPCDCDIGGAYSNVCSPKNGQCECR-PHVTGRSCSEPAPGYF 544
C PC C GA +++C+ GQC C+ + G+ C + YF
Sbjct: 948 CLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYF 990
Score = 147 bits (370), Expect = 1e-34
Identities = 98/313 (31%), Positives = 142/313 (45%), Gaps = 70/313 (22%)
Query: 266 FCNGHASECRPMQKMRG-------------DVF-----------SPPGMV----HGQCVC 297
FCN H+ +C ++ +G DV S PG V GQC+C
Sbjct: 758 FCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQCIC 817
Query: 298 QHNTDGPNCERCKD--FFQDAPWRPAADLQDNA--CRSCSCNSHSSRCHFDMTTYLASGG 353
+ N +G C +C + F+ Q+N+ C C+C+ T +G
Sbjct: 818 KPNVEGRQCNKCLEGNFYLR---------QNNSFLCLPCNCDK----------TGTINGS 858
Query: 354 L----SGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICV 409
L S G C C+ G C++C P Y TI + C CECD GT+ G IC
Sbjct: 859 LLCNKSTGQCP-CKLGVTGLRCNQCEPHRYN---LTIDNFQHCQMCECDSLGTLPGTIC- 913
Query: 410 SHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCD 469
DP ++GQCLC N +G +C+QC+P Y +S + GC PC C+ G++ + C+
Sbjct: 914 ---DP----ISGQCLCVPNRQGRRCNQCQPGFY-ISPGNATGCLPCSCHTTGAVNHI-CN 964
Query: 470 VDTGQCLCL-SYVTGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYSNVCSPKNGQCECR 528
TGQC+C + + G C++C Y+G C PC+C + GA + C GQC C+
Sbjct: 965 SLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFCK 1024
Query: 529 PHVTGRSCSEPAP 541
VTG C P
Sbjct: 1025 QFVTGSKCDACVP 1037
Score = 108 bits (269), Expect = 6e-23
Identities = 54/138 (39%), Positives = 74/138 (53%), Gaps = 12/138 (8%)
Query: 769 CKCHPQGSV-GSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHH--GCHPCHCHPQGSK 825
C+C G++ G+ C + GQC C P GR C++C G Y + GC PC CH G+
Sbjct: 900 CECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAV 959
Query: 826 DTVCDQVTGQCPCH-GEVSGRRCDRCLAGYFGFPS----CHPCPCN---RFAELCDPETG 877
+ +C+ +TGQC C ++G+RCD+C YFGF C PC C+ E C TG
Sbjct: 960 NHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTG 1019
Query: 878 SCFNCGGFTTGRNCERCI 895
CF C F TG C+ C+
Sbjct: 1020 QCF-CKQFVTGSKCDACV 1036
Score = 78.6 bits (192), Expect = 5e-14
Identities = 52/181 (28%), Positives = 77/181 (42%), Gaps = 32/181 (17%)
Query: 273 ECRPMQKMRGDVFSPPGMVHGQCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSC 332
EC + + G + P + GQC+C N G C +C+ F +P C C
Sbjct: 901 ECDSLGTLPGTICDP---ISGQCLCVPNRQGRRCNQCQPGFYISPGNATG------CLPC 951
Query: 333 SCNSHSSRCHFDMTTYLASGGLSGG-VCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYA 391
SC++ + H L+G VC+D + GQ CD+C+ ++ +T
Sbjct: 952 SCHTTGAVNHI-------CNSLTGQCVCQDA--SIAGQRCDQCKDHYFGFDPQT----GR 998
Query: 392 CIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLG 451
C PC C G ++ V GQC CK+ V G+KCD C P+ L + LG
Sbjct: 999 CQPCNCHLSGALN---------ETCHLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLG 1049
Query: 452 C 452
C
Sbjct: 1050 C 1050
Score = 78.6 bits (192), Expect = 5e-14
Identities = 35/90 (38%), Positives = 49/90 (54%), Gaps = 3/90 (3%)
Query: 765 GAVACKCHPQGSVGSSCSRLGGQCQCKPL-VVGRCCDRCSTG--SYDLGHHGCHPCHCHP 821
G + C CH G+V C+ L GQC C+ + G+ CD+C +D C PC+CH
Sbjct: 947 GCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHL 1006
Query: 822 QGSKDTVCDQVTGQCPCHGEVSGRRCDRCL 851
G+ + C VTGQC C V+G +CD C+
Sbjct: 1007 SGALNETCHLVTGQCFCKQFVTGSKCDACV 1036
Score = 68.2 bits (165), Expect = 7e-11
Identities = 52/169 (30%), Positives = 71/169 (42%), Gaps = 26/169 (15%)
Query: 402 TISGGI-CVSHSDPA-LGSVAGQCLCKEN--VEGAKCDQCKP--NHYGLSATDPL---GC 452
TISG C H+D S +CLC + EG CD+C P N D + C
Sbjct: 513 TISGRCQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNC 572
Query: 453 QPCDCNPLGSLPFLTCDVDT----------GQCL-CLSYVTGAHCEECTVGYWGL----G 497
+PC CN VD G C C TG +CE C ++
Sbjct: 573 KPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADP 632
Query: 498 NHLHGCSPCDCDIGGAYSN--VCSPKNGQCECRPHVTGRSCSEPAPGYF 544
+ + C PCDCD G + +C GQC C+ HV+GR C++ G++
Sbjct: 633 SAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFY 681
>gi|148613884 netrin 1 [Homo sapiens]
Length = 604
Score = 246 bits (628), Expect = 1e-64
Identities = 146/424 (34%), Positives = 219/424 (51%), Gaps = 51/424 (12%)
Query: 28 CHPTTGDLLVGRNTQLMASSTCGLSRAQKYCILSYLEGEQK---CFICDSRFPYDPYDQP 84
C P + G++ ++ SSTCG A +YC++S GE++ C +C++ P +
Sbjct: 51 CIPDFVNAAFGKDVRV--SSTCGRPPA-RYCVVSE-RGEERLRSCHLCNASDPKKAHPPA 106
Query: 85 NSHTIENVIVSFEPDREKKWWQSENGLD---HVSIRLDLEALFRFSHLILTFKTFRPAAM 141
+ N WQSEN L +V++ L L F +++ L F + RP +M
Sbjct: 107 FLTDLNN-------PHNLTCWQSENYLQFPHNVTLTLSLGKKFEVTYVSLQFCSPRPESM 159
Query: 142 LVERSTDYGHNWKVFKYFAKDCATSF--PNITSGQAQGVGDIVCDSKYSDIEPSTGGEVV 199
+ +S DYG W F++++ C + P+ Q + VC ++D+ P +GG +
Sbjct: 160 AIYKSMDYGRTWVPFQFYSTQCRKMYNRPHRAPITKQNEQEAVCTDSHTDMRPLSGGLIA 219
Query: 200 LKVLD---PSFEIENPYSPYIQDLVTLTNLRINFTKLHTLGDALLGRRQNDS---LDKYY 253
LD + + +N SP +QD VT T++R+ F++LHT GD ++DS D Y+
Sbjct: 220 FSTLDGRPSAHDFDN--SPVLQDWVTATDIRVAFSRLHTFGD----ENEDDSELARDSYF 273
Query: 254 YALYEMIVRGSCFCNGHASECRPMQKMRGDVFSPPGMVHGQCVCQHNTDGPNCERCKDFF 313
YA+ ++ V G C CNGHA+ C + R D C C+HNT GP C+RCK F
Sbjct: 274 YAVSDLQVGGRCKCNGHAARC---VRDRDDSLV--------CDCRHNTAGPECDRCKPFH 322
Query: 314 QDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDR 373
D PW+ A + N C +C+CN H+ RC F+M Y SG SGGVC +C+HNT G+HC
Sbjct: 323 YDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHY 382
Query: 374 CRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAK 433
C+ +YRD K I+ AC C+C P G +G C GQC CK+ V G
Sbjct: 383 CKEGYYRDMGKPITHRKACKACDCHPVGA-AGKTC--------NQTTGQCPCKDGVTGIT 433
Query: 434 CDQC 437
C++C
Sbjct: 434 CNRC 437
Score = 89.4 bits (220), Expect = 3e-17
Identities = 54/176 (30%), Positives = 74/176 (42%), Gaps = 26/176 (14%)
Query: 936 VICNCLQGYTGTQCGECSTGFYGNP--RISGAPCQPC-ACNNNIDVTDPE--------SC 984
++C+C G +C C Y P R + C ACN N+ S
Sbjct: 302 LVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSG 361
Query: 985 SRVTGECLRCLHNTQGANCQLCKPGHY---GSALN--QTCRRCSCHASGVSPMECPPGGG 1039
+ G CL C HNT G +C CK G+Y G + + C+ C CH P G
Sbjct: 362 RKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCH---------PVGAA 412
Query: 1040 ACLCDPVTGACPCLPNVTGLACDRCADGY-WNLVPGRGCQSCDCDPRTSQSSHCDQ 1094
C+ TG CPC VTG+ C+RCA GY + P C P T+ +S ++
Sbjct: 413 GKTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVAPPTTAASSVEE 468
Score = 82.0 bits (201), Expect = 5e-15
Identities = 52/153 (33%), Positives = 66/153 (43%), Gaps = 22/153 (14%)
Query: 408 CVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYG-----LSATDPLGCQPCDCNPLG- 461
CV D +L C C+ N G +CD+CKP HY +A + C C+CN
Sbjct: 294 CVRDRDDSL-----VCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHAR 348
Query: 462 ------SLPFLTCDVDTGQCL-CLSYVTGAHCEECTVGYW-GLGN---HLHGCSPCDCDI 510
L L+ G CL C G HC C GY+ +G H C CDC
Sbjct: 349 RCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHP 408
Query: 511 GGAYSNVCSPKNGQCECRPHVTGRSCSEPAPGY 543
GA C+ GQC C+ VTG +C+ A GY
Sbjct: 409 VGAAGKTCNQTTGQCPCKDGVTGITCNRCAKGY 441
Score = 77.4 bits (189), Expect = 1e-13
Identities = 49/170 (28%), Positives = 68/170 (40%), Gaps = 32/170 (18%)
Query: 1038 GGACLCDPVTG----------ACPCLPNVTGLACDRCA----DGYWNLVPGRG---CQSC 1080
GG C C+ C C N G CDRC D W R C +C
Sbjct: 282 GGRCKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVAC 341
Query: 1081 DCD---PRTSQSSHCDQLTGQ------CPCKLGYGGKRCSECQENYYGDPPG------RC 1125
+C+ R + +L+G+ C+ G+ C C+E YY D C
Sbjct: 342 NCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKAC 401
Query: 1126 IPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDRCARGHSQEFPTCLQC 1175
CDC+ G C+ TG C C++GV+G C+RCA+G+ Q C
Sbjct: 402 KACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPC 451
Score = 68.6 bits (166), Expect = 5e-11
Identities = 33/77 (42%), Positives = 39/77 (50%), Gaps = 7/77 (9%)
Query: 785 GGQC-QCKPLVVGRCCDRCSTGSY-DLG-----HHGCHPCHCHPQGSKDTVCDQVTGQCP 837
GG C C+ GR C C G Y D+G C C CHP G+ C+Q TGQCP
Sbjct: 365 GGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQTTGQCP 424
Query: 838 CHGEVSGRRCDRCLAGY 854
C V+G C+RC GY
Sbjct: 425 CKDGVTGITCNRCAKGY 441
Score = 66.2 bits (160), Expect = 3e-10
Identities = 50/180 (27%), Positives = 68/180 (37%), Gaps = 42/180 (23%)
Query: 836 CPCHGEVSGRRCDRCLAGYFGFP----------SCHPCPCNRFAELCD-----------P 874
C C +G CDRC ++ P C C CN A C
Sbjct: 304 CDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRK 363
Query: 875 ETGSCFNCGGFTTGRNCERCIDGYY---GNP-SSGQPCRPCLCPDDPSSNQYFAHSCYQN 930
G C NC T GR+C C +GYY G P + + C+ C C ++ + +C Q
Sbjct: 364 SGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGK----TCNQT 419
Query: 931 LWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPC------QPCACNNNIDVTDPESC 984
C C G TG C C+ G Y R APC P ++++ +PE C
Sbjct: 420 TGQ----CPCKDGVTGITCNRCAKG-YQQSRSPIAPCIKIPVAPPTTAASSVE--EPEDC 472
Score = 52.8 bits (125), Expect = 3e-06
Identities = 25/65 (38%), Positives = 31/65 (47%), Gaps = 1/65 (1%)
Query: 768 ACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHGCHPCHCHPQGSKDT 827
AC CHP G+ G +C++ GQC CK V G C+RC+ G Y PC P T
Sbjct: 403 ACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAKG-YQQSRSPIAPCIKIPVAPPTT 461
Query: 828 VCDQV 832
V
Sbjct: 462 AASSV 466
>gi|5453810 netrin 3 [Homo sapiens]
Length = 580
Score = 210 bits (534), Expect = 1e-53
Identities = 135/421 (32%), Positives = 202/421 (47%), Gaps = 60/421 (14%)
Query: 28 CHPTTGDLLVGRNTQLMASSTCGLSRAQKYCILSYLEGEQKCFICDSRFPYDPYDQPNSH 87
C P + +GR +++ASSTCG + C D R + P
Sbjct: 40 CVPGLVNAALGR--EVLASSTCGRPATRA------------CDASDPRRAHSPA------ 79
Query: 88 TIENVIVSFEPDREKKWWQSEN---GLDHVSIRLDLEALFRFSHLILTFKTFRPAAMLVE 144
++ S W+SE+ +V++ + L F + L F + PA++ +
Sbjct: 80 ----LLTSPGGTASPLCWRSESLPRAPLNVTLTVPLGKAFELVFVSLRFCSAPPASVALL 135
Query: 145 RSTDYGHNWKVFKYFAKDCATSF---PNITSGQAQGVGDIVCDSKYSDIEPSTGGEVVLK 201
+S D+G +W +F+ C + P +G A + +C +P G +
Sbjct: 136 KSQDHGRSWAPLGFFSSHCDLDYGRLPAPANGPAGPGPEALCFPAPL-AQPDGSGLLAFS 194
Query: 202 VLD---PSFEIENPYSPYIQDLVTLTNLRINFTKLHTLGDALLGRRQNDSLDKYYYALYE 258
+ D P ++++ SP +QD VT T++R+ T+ T GD R +++ Y YA +
Sbjct: 195 MQDSSPPGLDLDS--SPVLQDWVTATDVRVVLTRPSTAGDP----RDMEAVVPYSYAATD 248
Query: 259 MIVRGSCFCNGHASECRPMQKMRGDVFSPPGMVHGQCVCQHNTDGPNCERCKDFFQDAPW 318
+ V G C CNGHAS C + G H C C+H T+GP+C RCK F+ D PW
Sbjct: 249 LQVGGRCKCNGHASRC---------LLDTQG--HLICDCRHGTEGPDCGRCKPFYCDRPW 297
Query: 319 RPAADLQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLF 378
+ A + +AC +CSCN H+ RC F+M Y SG SGGVC +C+HNT G+HC CR F
Sbjct: 298 QRATARESHACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGF 357
Query: 379 YRDPLKTISDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCK 438
YRDP + +SD AC C+C P G +G C GQC CK+ V G C++C
Sbjct: 358 YRDPGRALSDRRACRACDCHPVGA-AGKTC--------NQTTGQCPCKDGVTGLTCNRCA 408
Query: 439 P 439
P
Sbjct: 409 P 409
Score = 95.1 bits (235), Expect = 5e-19
Identities = 68/204 (33%), Positives = 86/204 (42%), Gaps = 33/204 (16%)
Query: 936 VICNCLQGYTGTQCGECSTGFYGNP------RISGAPCQPCACNN-------NIDVTDPE 982
+IC+C G G CG C + P R S A C C+CN N+++
Sbjct: 272 LICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHA-CLACSCNGHARRCRFNMELYRL- 329
Query: 983 SCSRVTGECLRCLHNTQGANCQLCKPGHY---GSALN--QTCRRCSCHASGVSPMECPPG 1037
S R G CL C HNT G +C C+ G Y G AL+ + CR C CH P G
Sbjct: 330 SGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCH---------PVG 380
Query: 1038 GGACLCDPVTGACPCLPNVTGLACDRCADGY-WNLVPGRGCQSCDCDPRTSQSSHCDQLT 1096
C+ TG CPC VTGL C+RCA G+ + P C T SS
Sbjct: 381 AAGKTCNQTTGQCPCKDGVTGLTCNRCAPGFQQSRSPVAPCVKTPIPGPTEDSSPVQPQD 440
Query: 1097 GQCPCKLGYGGKRCS---ECQENY 1117
CK G R S C+++Y
Sbjct: 441 CDSHCKPARGSYRISLKKFCKKDY 464
Score = 74.3 bits (181), Expect = 1e-12
Identities = 57/194 (29%), Positives = 72/194 (37%), Gaps = 39/194 (20%)
Query: 1008 PGHYGSALNQTCRRCSC--HASGVSPMECPPGGGACLCDPVTGA-CPCLPNVTGLACDRC 1064
P Y + Q RC C HAS CL D C C G C RC
Sbjct: 241 PYSYAATDLQVGGRCKCNGHAS------------RCLLDTQGHLICDCRHGTEGPDCGRC 288
Query: 1065 ADGY----WNLVPGR---GCQSCDCDPRTSQSSHCDQLT--------GQC-PCKLGYGGK 1108
Y W R C +C C+ + +L G C C+ G+
Sbjct: 289 KPFYCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGR 348
Query: 1109 RCSECQENYYGDPPGR-------CIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDRC 1161
C C+E +Y DP GR C CDC+ G C+ TG C C++GV+G C+RC
Sbjct: 349 HCHYCREGFYRDP-GRALSDRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRC 407
Query: 1162 ARGHSQEFPTCLQC 1175
A G Q C
Sbjct: 408 APGFQQSRSPVAPC 421
Score = 71.2 bits (173), Expect = 8e-12
Identities = 48/155 (30%), Positives = 62/155 (40%), Gaps = 19/155 (12%)
Query: 408 CVSHSDPALGSVAGQ--CLCKENVEGAKCDQCKPNHYG-----LSATDPLGCQPCDCNPL 460
C H+ L G C C+ EG C +CKP + +A + C C CN
Sbjct: 257 CNGHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCNGH 316
Query: 461 G-------SLPFLTCDVDTGQCL-CLSYVTGAHCEECTVGYW-GLGNHL---HGCSPCDC 508
L L+ G CL C G HC C G++ G L C CDC
Sbjct: 317 ARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDC 376
Query: 509 DIGGAYSNVCSPKNGQCECRPHVTGRSCSEPAPGY 543
GA C+ GQC C+ VTG +C+ APG+
Sbjct: 377 HPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGF 411
Score = 69.3 bits (168), Expect = 3e-11
Identities = 41/122 (33%), Positives = 52/122 (42%), Gaps = 15/122 (12%)
Query: 748 PGACERLIISMSAKLHDGAVACKCHPQGS--------VGSSCSRLGGQC-QCKPLVVGRC 798
P C+R +A+ +AC C+ S R GG C C+ GR
Sbjct: 290 PFYCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRH 349
Query: 799 CDRCSTGSY-DLGH-----HGCHPCHCHPQGSKDTVCDQVTGQCPCHGEVSGRRCDRCLA 852
C C G Y D G C C CHP G+ C+Q TGQCPC V+G C+RC
Sbjct: 350 CHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAP 409
Query: 853 GY 854
G+
Sbjct: 410 GF 411
Score = 68.2 bits (165), Expect = 7e-11
Identities = 61/233 (26%), Positives = 83/233 (35%), Gaps = 53/233 (22%)
Query: 817 CHCHPQGSKDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFP----------SCHPCPCN 866
C C+ S+ + Q C C G C RC Y P +C C CN
Sbjct: 255 CKCNGHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCN 314
Query: 867 RFAELCD-----------PETGSCFNCGGFTTGRNCERCIDGYYGNP----SSGQPCRPC 911
A C G C NC T GR+C C +G+Y +P S + CR C
Sbjct: 315 GHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRAC 374
Query: 912 LCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCA 971
C ++ + +C Q C C G TG C C+ GF + S +P PC
Sbjct: 375 DCHPVGAAGK----TCNQTTGQ----CPCKDGVTGLTCNRCAPGF----QQSRSPVAPCV 422
Query: 972 CNNNIDVTDPESCSRVTGECLRCLHNTQGANCQL-CKP--GHYGSALNQTCRR 1021
T+ S Q +C CKP G Y +L + C++
Sbjct: 423 KTPIPGPTEDSS-------------PVQPQDCDSHCKPARGSYRISLKKFCKK 462
>gi|164414431 netrin G1 isoform 1 [Homo sapiens]
Length = 539
Score = 180 bits (457), Expect = 1e-44
Identities = 147/513 (28%), Positives = 230/513 (44%), Gaps = 113/513 (22%)
Query: 27 ACHPTTGDLLVGRNTQLMASS-TCGLSRAQKYCILS--YLEGEQKCFICDSRFPYDPYDQ 83
AC P + D+ +L TCG + +C + Y+ + CD+ P
Sbjct: 49 ACQPESTDMTKYLKVKLDPPDITCG-DPPETFCAMGNPYMCNNE----CDASTP------ 97
Query: 84 PNSHTIENVIVSFEPDREKKWWQSENGLDH-----VSIRLDLEALFRFS-HLILTFKTFR 137
+H E ++ FE +WQS ++ V+I L + ++++TF++ R
Sbjct: 98 ELAHPPE-LMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGR 156
Query: 138 PAAMLVERSTDYGHNWKVFKYFAKDCATSF----PNITSGQAQGVGDIVCDSKYSDIEPS 193
P M++E+S DYG W+ ++Y+A DC +F ++ V +I+C +YS
Sbjct: 157 PDQMILEKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQHTVLEIICTEEYS----- 211
Query: 194 TGGEVVLKVLDPSFEIENPYSPY--------------------IQDLVTLTNLRINFTKL 233
TG K++ FEI++ ++ + ++D T+T+LRI +
Sbjct: 212 TGYTTNSKIIH--FEIKDRFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDLRIRLLR- 268
Query: 234 HTLGDALLGRRQNDSLDKYYYALYEMIVRGSCFCNGHASECRPMQKMRGDVFSPPGMVHG 293
+G+ + L +Y+YA+ ++ VRG C CN HA+ C V+ +
Sbjct: 269 PAVGEIFVDELH---LARYFYAISDIKVRGRCKCNLHATVC---------VYDNSKLT-- 314
Query: 294 QCVCQHNTDGPNCERCKDFFQDAPWRPAADLQ-----DNAC-------RSCSCNSHSSRC 341
C C+HNT GP+C +CK +Q PW P + L N C +C C HS+RC
Sbjct: 315 -CECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRC 373
Query: 342 HF-DMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPD 400
+ D+ L+ +C C+HNT GQHC+ CR ++R+ + D CI C C+P
Sbjct: 374 SYIDL--------LNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPL 425
Query: 401 GTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPN---HYGLSATDPLGCQP--C 455
G+I D GS G C CK G KCD+C P HY GCQP C
Sbjct: 426 GSI--------HDRCNGS--GFCECKTGTTGPKCDECLPGNSWHY--------GCQPNVC 467
Query: 456 DCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEE 488
D L TC + +CLC + TG CE+
Sbjct: 468 DNELLHCQNGGTCH-NNVRCLCPAAYTGILCEK 499
Score = 72.8 bits (177), Expect = 3e-12
Identities = 59/217 (27%), Positives = 83/217 (38%), Gaps = 56/217 (25%)
Query: 933 SSDVICNCLQGYTGTQCGECSTGFYGNPRISGA----------PCQP-------CACNNN 975
+S + C C TG CG+C + G P G+ C P C C +
Sbjct: 310 NSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGH 369
Query: 976 IDVTDPESCSRV----TGECLRCLHNTQGANCQLCKPGHYGSALNQ-----TCRRCSCHA 1026
+ CS + T C+ C HNT+G +C+LC+ G++ +A Q C C C+
Sbjct: 370 SN-----RCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNP 424
Query: 1027 SGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCADG-YWNLVPGRGCQSCDCDPR 1085
G C +G C C TG CD C G W+ GCQ CD
Sbjct: 425 LGSIHDRCNG----------SGFCECKTGTTGPKCDECLPGNSWHY----GCQPNVCD-- 468
Query: 1086 TSQSSHCD-----QLTGQCPCKLGYGGKRCSE--CQE 1115
++ HC +C C Y G C + C+E
Sbjct: 469 -NELLHCQNGGTCHNNVRCLCPAAYTGILCEKLRCEE 504
Score = 67.0 bits (162), Expect = 2e-10
Identities = 54/208 (25%), Positives = 84/208 (40%), Gaps = 52/208 (25%)
Query: 970 CACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQLCKPGHYGSALNQTCRRCSCHASGV 1029
C CN + V ++ S++T EC HNT G +C CK + G
Sbjct: 297 CKCNLHATVCVYDN-SKLTCECE---HNTTGPDCGKCKKNYQGR---------------- 336
Query: 1030 SPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCADGYWNLVPGRGCQSCDCDPRTSQS 1089
P G+ L P A C+P+++ + +C+C +++
Sbjct: 337 -----PWSPGSYLPIPKGTANTCIPSISSIG------------------NCECFGHSNRC 373
Query: 1090 SHCDQL-TGQC-PCKLGYGGKRCSECQENYYG------DPPGRCIPCDCNRAGTQKPICD 1141
S+ D L T C CK G+ C C+ Y+ D CI C CN G+ C+
Sbjct: 374 SYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCN 433
Query: 1142 PDTGMCRCREGVSGQRCDRCARGHSQEF 1169
+G C C+ G +G +CD C G+S +
Sbjct: 434 -GSGFCECKTGTTGPKCDECLPGNSWHY 460
Score = 56.6 bits (135), Expect = 2e-07
Identities = 59/227 (25%), Positives = 82/227 (36%), Gaps = 54/227 (23%)
Query: 808 DLGHHGCHPCHCHPQGSKDTVC--DQVTGQCPCHGEVSGRRCDRCLAGYFGFP------- 858
D+ G C+ H TVC D C C +G C +C Y G P
Sbjct: 290 DIKVRGRCKCNLHA-----TVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYL 344
Query: 859 --------SCHP-------CPC----NRFAELCDPETGSCFNCGGFTTGRNCERCIDGYY 899
+C P C C NR + + T C +C T G++CE C GY+
Sbjct: 345 PIPKGTANTCIPSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYF 404
Query: 900 GNPSS----GQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTG 955
N S+ C C C +P + + + C C G TG +C EC G
Sbjct: 405 RNASAQLDDENVCIECYC--NPLGS-------IHDRCNGSGFCECKTGTTGPKCDECLPG 455
Query: 956 ---FYG-NPRISGAPCQPC----ACNNNIDVTDPESCSRVTGECLRC 994
YG P + C C+NN+ P + + + E LRC
Sbjct: 456 NSWHYGCQPNVCDNELLHCQNGGTCHNNVRCLCPAAYTGILCEKLRC 502
Score = 53.1 bits (126), Expect = 2e-06
Identities = 40/134 (29%), Positives = 53/134 (39%), Gaps = 15/134 (11%)
Query: 790 CKPLVVGRCCDRCSTGSYDLG------HHGCHPCHCHPQGSKDTVCDQVTGQCPCHGEVS 843
CK G+ C+ C G + + C C+C+P GS C+ +G C C +
Sbjct: 387 CKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNG-SGFCECKTGTT 445
Query: 844 GRRCDRCLAGYFGFPSCHPCPCNRFAELCDPETGSCFN-----CGGFTTGRNCE--RCID 896
G +CD CL G C P C+ C G+C N C TG CE RC +
Sbjct: 446 GPKCDECLPGNSWHYGCQPNVCDNELLHCQ-NGGTCHNNVRCLCPAAYTGILCEKLRCEE 504
Query: 897 GYYGNPSSGQPCRP 910
SGQ P
Sbjct: 505 AGSCGSDSGQGAPP 518
Score = 52.0 bits (123), Expect = 5e-06
Identities = 38/142 (26%), Positives = 58/142 (40%), Gaps = 23/142 (16%)
Query: 423 CLCKENVEGAKCDQCKPNHYGLSATD------PLGCQPCDCNPLGSLPFLTCDVDTGQC- 475
C C+ N G C +CK N+ G + P G + S+ C + +C
Sbjct: 315 CECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCS 374
Query: 476 --------LCLSY---VTGAHCEECTVGYWGLGNHL----HGCSPCDCDIGGAYSNVCSP 520
+C+S G HCE C +GY+ + + C C C+ G+ + C+
Sbjct: 375 YIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNG 434
Query: 521 KNGQCECRPHVTGRSCSEPAPG 542
+G CEC+ TG C E PG
Sbjct: 435 -SGFCECKTGTTGPKCDECLPG 455
Score = 50.1 bits (118), Expect = 2e-05
Identities = 44/132 (33%), Positives = 52/132 (39%), Gaps = 32/132 (24%)
Query: 759 SAKLHDGAVA--CKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHGCHP 816
SA+L D V C C+P GS+ C+ G C+CK G CD C G + H+GC P
Sbjct: 408 SAQLDDENVCIECYCNPLGSIHDRCNG-SGFCECKTGTTGPKCDECLPG--NSWHYGCQP 464
Query: 817 CHCHPQGSKDTVCDQVTGQC----PCHGEVSGRRCDRCLAGYFGFPSCHPCPCNRFAELC 872
VCD C CH V RC C A Y G C C
Sbjct: 465 ----------NVCDNELLHCQNGGTCHNNV---RC-LCPAAYTGI-LCEKLRCE------ 503
Query: 873 DPETGSCFNCGG 884
E GSC + G
Sbjct: 504 --EAGSCGSDSG 513
>gi|122937440 multiple EGF-like-domains 9 [Homo sapiens]
Length = 639
Score = 174 bits (441), Expect = 7e-43
Identities = 90/248 (36%), Positives = 125/248 (50%), Gaps = 16/248 (6%)
Query: 769 CKCHPQGSVG-SSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHG-CHPCHCHPQGSKD 826
C C GS+ + C++ GQC+C+P G C+ C G Y G C PC C P G+
Sbjct: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALS 300
Query: 827 TVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFPS--CHPCPCNRFAELCDPETGSCFNCGG 884
C+ +G+C C V G CDRC GY+GF C PC CN + CD TG+C NC
Sbjct: 301 IPCNS-SGKCQCKVGVIGSICDRCQDGYYGFSKNGCLPCQCNNRSASCDALTGACLNCQE 359
Query: 885 FTTGRNCERCIDGYYGNPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICN-CLQG 943
+ G +CE C +G+Y +P + + C C C S+ SC + C+ C G
Sbjct: 360 NSKGNHCEECKEGFYQSPDATKECLRCPCSAVTSTG-----SCSIKSSELEPECDQCKDG 414
Query: 944 YTGTQCGECSTGFYGNPRISGAPCQPCACNNNID-VTDPESCSRVTGECLRCLHNTQGAN 1002
Y G C +C G+Y I C+ C C+ ++D V P+ C +GEC+ CLHNT G
Sbjct: 415 YIGPNCNKCENGYYNFDSI----CRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFW 470
Query: 1003 CQLCKPGH 1010
C+ C G+
Sbjct: 471 CENCLEGY 478
Score = 142 bits (357), Expect = 4e-33
Identities = 90/263 (34%), Positives = 118/263 (44%), Gaps = 36/263 (13%)
Query: 817 CHCHPQGSKDTV-CDQVTGQCPCHGEVSGRRCDRCLAG-YFGFPS--CHPCPCNRFAELC 872
C+C GS + C+Q TGQC C G C+ C G Y + S C PC C+ L
Sbjct: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALS 300
Query: 873 DP--ETGSCFNCGGFTTGRNCERCIDGYYGNPSSGQPCRPCLCPDDPSSNQYFAHSCYQN 930
P +G C C G C+RC DGYYG +G C PC C + +S +C
Sbjct: 301 IPCNSSGKC-QCKVGVIGSICDRCQDGYYGFSKNG--CLPCQCNNRSASCDALTGACL-- 355
Query: 931 LWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCS----R 986
NC + G C EC GFY +P + C C C+ VT SCS
Sbjct: 356 --------NCQENSKGNHCEECKEGFYQSPDAT-KECLRCPCSA---VTSTGSCSIKSSE 403
Query: 987 VTGECLRCLHNTQGANCQLCKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPV 1046
+ EC +C G NC C+ G+Y + CR+C CH V P++ P +C P
Sbjct: 404 LEPECDQCKDGYIGPNCNKCENGYYN--FDSICRKCQCHGH-VDPVKTPK-----ICKPE 455
Query: 1047 TGAC-PCLPNVTGLACDRCADGY 1068
+G C CL N TG C+ C +GY
Sbjct: 456 SGECINCLHNTTGFWCENCLEGY 478
Score = 121 bits (303), Expect = 7e-27
Identities = 88/280 (31%), Positives = 112/280 (40%), Gaps = 49/280 (17%)
Query: 863 CPCNRFAEL----CDPETGSCFNCGGFTTGRNCERCIDGYYGNPSSGQPCRPCLCPDDPS 918
C C+ L C+ TG C C G +CE C +G+Y N +SG C+PC C
Sbjct: 241 CNCSVVGSLNVNRCNQTTGQC-ECRPGYQGLHCETCKEGFYLNYTSGL-CQPCDCSP--- 295
Query: 919 SNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCACNNNIDV 978
H +S C C G G+ C C G+YG S C PC CNN
Sbjct: 296 ------HGALSIPCNSSGKCQCKVGVIGSICDRCQDGYYG---FSKNGCLPCQCNNR--- 343
Query: 979 TDPESCSRVTGECLRCLHNTQGANCQLCKPGHYGSA-LNQTCRRCSCHA------SGVSP 1031
SC +TG CL C N++G +C+ CK G Y S + C RC C A +
Sbjct: 344 --SASCDALTGACLNCQENSKGNHCEECKEGFYQSPDATKECLRCPCSAVTSTGSCSIKS 401
Query: 1032 MECPPGGGACLCDPVTGACPCLPNVTGLACDRCADGYWNLVPGRGCQSCDC----DPRTS 1087
E P CD C G C++C +GY+N C+ C C DP
Sbjct: 402 SELEPE-----CDQ------CKDGYIGPNCNKCENGYYNF--DSICRKCQCHGHVDP-VK 447
Query: 1088 QSSHCDQLTGQC-PCKLGYGGKRCSECQENYYGDPPGRCI 1126
C +G+C C G C C E Y D G CI
Sbjct: 448 TPKICKPESGECINCLHNTTGFWCENCLEGYVHDLEGNCI 487
Score = 116 bits (290), Expect = 2e-25
Identities = 69/231 (29%), Positives = 101/231 (43%), Gaps = 35/231 (15%)
Query: 959 NPRISGAPCQPCACNNNI-DVTDPESCSRVTGECLRCLHNTQGANCQLCKPGHYGSALNQ 1017
N R+S A CN ++ + C++ TG+C C QG +C+ CK G Y + +
Sbjct: 228 NLRVSEAVKTEYVCNCSVVGSLNVNRCNQTTGQC-ECRPGYQGLHCETCKEGFYLNYTSG 286
Query: 1018 TCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCADGYWNLVPGRGC 1077
C+ C C G + C +G C C V G CDRC DGY+ GC
Sbjct: 287 LCQPCDCSPHGALSIPCNS----------SGKCQCKVGVIGSICDRCQDGYYGF-SKNGC 335
Query: 1078 QSCDCDPRTSQSSHCDQLTGQC-PCKLGYGGKRCSECQENYYGDPPG--RCIPCDCN--- 1131
C C+ R S+ CD LTG C C+ G C EC+E +Y P C+ C C+
Sbjct: 336 LPCQCNNR---SASCDALTGACLNCQENSKGNHCEECKEGFYQSPDATKECLRCPCSAVT 392
Query: 1132 -------RAGTQKPICDPDTGMCRCREGVSGQRCDRCARGHSQEFPTCLQC 1175
++ +P CD +C++G G C++C G+ C +C
Sbjct: 393 STGSCSIKSSELEPECD------QCKDGYIGPNCNKCENGYYNFDSICRKC 437
Score = 109 bits (273), Expect = 2e-23
Identities = 50/137 (36%), Positives = 65/137 (47%), Gaps = 5/137 (3%)
Query: 1043 CDPVTGACPCLPNVTGLACDRCADGYWNLVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCK 1102
C+ TG C C P GL C+ C +G++ CQ CDC P + S C+ +G+C CK
Sbjct: 254 CNQTTGQCECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALSIPCNS-SGKCQCK 312
Query: 1103 LGYGGKRCSECQENYYGDPPGRCIPCDCNRAGTQKPICDPDTGMC-RCREGVSGQRCDRC 1161
+G G C CQ+ YYG C+PC CN CD TG C C+E G C+ C
Sbjct: 313 VGVIGSICDRCQDGYYGFSKNGCLPCQCNNRSAS---CDALTGACLNCQENSKGNHCEEC 369
Query: 1162 ARGHSQEFPTCLQCHLC 1178
G Q +C C
Sbjct: 370 KEGFYQSPDATKECLRC 386
Score = 100 bits (248), Expect = 2e-20
Identities = 63/194 (32%), Positives = 90/194 (46%), Gaps = 30/194 (15%)
Query: 357 GVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSHSDPAL 416
G CE C+ +G HC+ C+ FY + + C PC+C P G +S C S
Sbjct: 259 GQCE-CRPGYQGLHCETCKEGFYLNYTSGL-----CQPCDCSPHGALSIP-CNS------ 305
Query: 417 GSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCL 476
+G+C CK V G+ CD+C+ +YG S GC PC CN + +CD TG CL
Sbjct: 306 ---SGKCQCKVGVIGSICDRCQDGYYGFSKN---GCLPCQCNNRSA----SCDALTGACL 355
Query: 477 -CLSYVTGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYSNVCSPKNGQCE-----CRPH 530
C G HCEEC G++ + C C C + CS K+ + E C+
Sbjct: 356 NCQENSKGNHCEECKEGFYQSPDATKECLRCPCS-AVTSTGSCSIKSSELEPECDQCKDG 414
Query: 531 VTGRSCSEPAPGYF 544
G +C++ GY+
Sbjct: 415 YIGPNCNKCENGYY 428
Score = 97.4 bits (241), Expect = 1e-19
Identities = 69/247 (27%), Positives = 103/247 (41%), Gaps = 41/247 (16%)
Query: 253 YYALYEMIVRGSCFCNGHASECRPMQKMRGDVFSPPGMVHGQCVCQHNTDGPNCERCKDF 312
Y L+ + + N + C+P S P G+C C+ G C+RC+D
Sbjct: 267 YQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALSIPCNSSGKCQCKVGVIGSICDRCQDG 326
Query: 313 FQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCD 372
+ N C C CN+ S+ C D T G C +CQ N++G HC+
Sbjct: 327 YY--------GFSKNGCLPCQCNNRSASC--DALT---------GACLNCQENSKGNHCE 367
Query: 373 RCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQC-LCKENVEG 431
C+ FY+ P T C+ C C S G C S + +C CK+ G
Sbjct: 368 ECKEGFYQSPDAT----KECLRCPC--SAVTSTGSCSIKS----SELEPECDQCKDGYIG 417
Query: 432 AKCDQCKPNHYGLSATDPLGCQPCDCNPLGSL-PFLT---CDVDTGQCL-CLSYVTGAHC 486
C++C+ +Y + C+ C C+ G + P T C ++G+C+ CL TG C
Sbjct: 418 PNCNKCENGYYNFDSI----CRKCQCH--GHVDPVKTPKICKPESGECINCLHNTTGFWC 471
Query: 487 EECTVGY 493
E C GY
Sbjct: 472 ENCLEGY 478
Score = 87.4 bits (215), Expect = 1e-16
Identities = 64/257 (24%), Positives = 104/257 (40%), Gaps = 43/257 (16%)
Query: 293 GQCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASG 352
GQC C+ G +CE CK+ F + C+ C C+ H + L+
Sbjct: 259 GQCECRPGYQGLHCETCKEGFY-------LNYTSGLCQPCDCSPHGA---------LSIP 302
Query: 353 GLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSHS 412
S G C+ C+ G CDRC+ +Y C+PC+C ++
Sbjct: 303 CNSSGKCQ-CKVGVIGSICDRCQDGYYG------FSKNGCLPCQC------------NNR 343
Query: 413 DPALGSVAGQCL-CKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPL---GSLPFLTC 468
+ ++ G CL C+EN +G C++CK Y S C C C+ + GS +
Sbjct: 344 SASCDALTGACLNCQENSKGNHCEECKEGFY-QSPDATKECLRCPCSAVTSTGSCSIKSS 402
Query: 469 DVDTGQCLCLSYVTGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYS-NVCSPKNGQC-E 526
+++ C G +C +C GY+ + C C + + +C P++G+C
Sbjct: 403 ELEPECDQCKDGYIGPNCNKCENGYYNFDSICRKCQ-CHGHVDPVKTPKICKPESGECIN 461
Query: 527 CRPHVTGRSCSEPAPGY 543
C + TG C GY
Sbjct: 462 CLHNTTGFWCENCLEGY 478
Score = 72.0 bits (175), Expect = 5e-12
Identities = 36/91 (39%), Positives = 49/91 (53%), Gaps = 4/91 (4%)
Query: 455 CDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGLGNHLHG-CSPCDCDIGGA 513
C+C+ +GSL C+ TGQC C G HCE C G++ N+ G C PCDC GA
Sbjct: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFY--LNYTSGLCQPCDCSPHGA 298
Query: 514 YSNVCSPKNGQCECRPHVTGRSCSEPAPGYF 544
S C+ +G+C+C+ V G C GY+
Sbjct: 299 LSIPCN-SSGKCQCKVGVIGSICDRCQDGYY 328
Score = 42.4 bits (98), Expect = 0.004
Identities = 23/85 (27%), Positives = 34/85 (40%), Gaps = 14/85 (16%)
Query: 297 CQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASGGLSG 356
C+ GPNC +C++ + + D+ CR C C+ H SG
Sbjct: 411 CKDGYIGPNCNKCENGYYNF---------DSICRKCQCHGHVDPVKTPKICKPESGE--- 458
Query: 357 GVCEDCQHNTEGQHCDRCRPLFYRD 381
C +C HNT G C+ C + D
Sbjct: 459 --CINCLHNTTGFWCENCLEGYVHD 481
>gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]
Length = 1044
Score = 171 bits (434), Expect = 4e-42
Identities = 141/444 (31%), Positives = 180/444 (40%), Gaps = 97/444 (21%)
Query: 765 GAVACKCHPQGSVGSSCSR------------LGGQCQCKPLVVG-RCCDRCSTGSYDLGH 811
GAV + P G+ G +CS+ + GQC C +G RC + C GS+ G
Sbjct: 255 GAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSF--GF 312
Query: 812 HGCHPCHCHPQGSKDTVCDQVTGQCPCHGEVSGRRCDR--CLAGYFGFPSCH-PCPCNRF 868
C CH G C TG C C G RC C G G P C PCPC+
Sbjct: 313 QCSQHCDCHNGGQ----CSPTTGACECEPGYKGPRCQERLCPEGLHG-PGCTLPCPCDAD 367
Query: 869 AEL-CDPETGSCFNCGGFTTGRNC-ERCIDGYYGNPSSGQPCRPCLCPDDPSSNQYFAHS 926
+ C P TG+C C +G +C E C GYYG+ PC C N HS
Sbjct: 368 NTISCHPVTGAC-TCQPGWSGHHCNESCPVGYYGDGCQ----LPCTC-----QNGADCHS 417
Query: 927 CYQNLWSSDVICNCLQGYTGTQCG-ECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCS 985
C C G+ G C C+ G YG P S C+CNN +CS
Sbjct: 418 ITGG-------CTCAPGFMGEVCAVSCAAGTYG-PNCSSI----CSCNNG------GTCS 459
Query: 986 RVTGECLRCLHNTQGANCQL-CKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCD 1044
V G C C QG +C L C G +G N++ C+C A+G + C
Sbjct: 460 PVDGSC-TCKEGWQGLDCTLPCPSGTWGLNCNES---CTC-ANGAA------------CS 502
Query: 1045 PVTGACPCLPNVTGLACD-RCADGYWNLVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKL 1103
P+ G+C C P G C+ C DG + L + CDC S + CD +TG C C
Sbjct: 503 PIDGSCSCTPGWLGDTCELPCPDGTFGL---NCSEHCDC----SHADGCDPVTGHCCCLA 555
Query: 1104 GYGGKRC-SECQENYYGDPPGRCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDRC- 1161
G+ G RC S C +G P + C C G+ C P+ G C C G G C R
Sbjct: 556 GWTGIRCDSTCPPGRWG--PNCSVSCSCENGGS----CSPEDGSCECAPGFRGPLCQRIC 609
Query: 1162 -----ARGHSQEFPTCLQ----CH 1176
G +Q P C+ CH
Sbjct: 610 PPGFYGHGCAQPCPLCVHSSRPCH 633
Score = 171 bits (432), Expect = 8e-42
Identities = 132/403 (32%), Positives = 175/403 (43%), Gaps = 76/403 (18%)
Query: 768 ACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDR-CSTGSYDLGHHGCHPCHCHPQGSKD 826
+C C + G++CS + G C C P +G C+ C G++ L C H S
Sbjct: 492 SCTC----ANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLN------CSEHCDCSHA 541
Query: 827 TVCDQVTGQCPCHGEVSGRRCDR-CLAGYFGFPSCH-PCPCNRFAELCDPETGSCFNCGG 884
CD VTG C C +G RCD C G +G P+C C C C PE GSC G
Sbjct: 542 DGCDPVTGHCCCLAGWTGIRCDSTCPPGRWG-PNCSVSCSCENGGS-CSPEDGSCECAPG 599
Query: 885 FTTGRNCER-CIDGYYGNPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQG 943
F G C+R C G+YG+ QPC C+ P C+ IC CL G
Sbjct: 600 FR-GPLCQRICPPGFYGH-GCAQPCPLCVHSSRP---------CHH----ISGICECLPG 644
Query: 944 YTGTQCGE-CSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGAN 1002
++G C + C+ G++G Q C+C NN +CS + G C +C G +
Sbjct: 645 FSGALCNQVCAGGYFGQDC-----AQLCSCANN------GTCSPIDGSC-QCFPGWIGKD 692
Query: 1003 C-QLCKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLAC 1061
C Q C PG +G A C SCH +G S C GAC C P TGL C
Sbjct: 693 CSQACPPGFWGPACFHAC---SCH-NGAS------------CSAEDGACHCTPGWTGLFC 736
Query: 1062 -DRCADGYWNLVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSE-CQENYYG 1119
RC ++ GR CQ + CD ++G+C C+ G+ G+ C + C +G
Sbjct: 737 TQRCPAAFFGKDCGRVCQC-------QNGASCDHISGKCTCRTGFTGQHCEQRCAPGTFG 789
Query: 1120 DPPGRCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDRCA 1162
G C+C T CD TG C C G G RCD+ A
Sbjct: 790 Y--GCQQLCECMNNST----CDHVTGTCYCSPGFKGIRCDQAA 826
Score = 164 bits (415), Expect = 7e-40
Identities = 141/436 (32%), Positives = 172/436 (39%), Gaps = 91/436 (20%)
Query: 769 CKCHPQGSVGSSCSRLGGQCQCKPLVVG-RCCDRCSTGSYDLGHHGCHPCHCHPQGSKDT 827
C CH G C + GQC C +G RC + C GS+ G C CH G
Sbjct: 275 CPCHH----GGQCDHVTGQCHCTAGYMGDRCQEECPFGSF--GFQCSQHCDCHNGGQ--- 325
Query: 828 VCDQVTGQCPCHGEVSGRRCDR--CLAGYFGFPSCH-PCPCNRFAEL-CDPETGSCFNCG 883
C TG C C G RC C G G P C PCPC+ + C P TG+C C
Sbjct: 326 -CSPTTGACECEPGYKGPRCQERLCPEGLHG-PGCTLPCPCDADNTISCHPVTGAC-TCQ 382
Query: 884 GFTTGRNC-ERCIDGYYGNPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQ 942
+G +C E C GYYG+ PC C N HS C C
Sbjct: 383 PGWSGHHCNESCPVGYYGDGCQ----LPCTC-----QNGADCHSITGG-------CTCAP 426
Query: 943 GYTGTQCG-ECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGA 1001
G+ G C C+ G YG P S C+CNN +CS V G C C QG
Sbjct: 427 GFMGEVCAVSCAAGTYG-PNCSSI----CSCNNG------GTCSPVDGSCT-CKEGWQGL 474
Query: 1002 NCQL-CKPGHYGSALNQTCR------------RCSCHASGVSP---MECPPG--GGACL- 1042
+C L C G +G N++C CSC + + CP G G C
Sbjct: 475 DCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSE 534
Query: 1043 ---------CDPVTGACPCLPNVTGLACD-RCADGYWNLVPGRGCQ-SCDCDPRTSQSSH 1091
CDPVTG C CL TG+ CD C G W G C SC C+
Sbjct: 535 HCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRW----GPNCSVSCSCE----NGGS 586
Query: 1092 CDQLTGQCPCKLGYGGKRCSE-CQENYYGDPPGRCIPCDCNRAGTQKPICDPDTGMCRCR 1150
C G C C G+ G C C +YG G PC + +P C +G+C C
Sbjct: 587 CSPEDGSCECAPGFRGPLCQRICPPGFYGH--GCAQPCPL-CVHSSRP-CHHISGICECL 642
Query: 1151 EGVSGQRCDR-CARGH 1165
G SG C++ CA G+
Sbjct: 643 PGFSGALCNQVCAGGY 658
Score = 151 bits (382), Expect = 5e-36
Identities = 141/464 (30%), Positives = 176/464 (37%), Gaps = 107/464 (23%)
Query: 769 CKCHPQGSVGSSCSRLGGQCQCKPLVVG-RCCDRCSTGSYDLGHHGCH-PCHCHPQGSKD 826
C C ++ SC + G C C+P G C + C G Y GC PC C Q D
Sbjct: 362 CPCDADNTI--SCHPVTGACTCQPGWSGHHCNESCPVGYYG---DGCQLPCTC--QNGAD 414
Query: 827 TVCDQVTGQCPCHGEVSGRRCD-RCLAGYFGFPSCHP-CPCNRFAELCDPETGSC----- 879
C +TG C C G C C AG +G P+C C CN C P GSC
Sbjct: 415 --CHSITGGCTCAPGFMGEVCAVSCAAGTYG-PNCSSICSCNN-GGTCSPVDGSCTCKEG 470
Query: 880 -------FNCGGFTTGRNCER---CIDGYYGNPSSGQ-PCRP--------CLCPDDPSSN 920
C T G NC C +G +P G C P CPD
Sbjct: 471 WQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGL 530
Query: 921 QYFAHSCYQNLWSSDVI---CNCLQGYTGTQC-GECSTGFYGNPRISGAPCQPCACNNNI 976
H + D + C CL G+TG +C C G +G P S + C+C N
Sbjct: 531 NCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWG-PNCSVS----CSCENG- 584
Query: 977 DVTDPESCSRVTGECLRCLHNTQGANCQ-LCKPGHYGSALNQTCRRC-----SC-HASGV 1029
SCS G C C +G CQ +C PG YG Q C C C H SG+
Sbjct: 585 -----GSCSPEDGSC-ECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGI 638
Query: 1030 SPMECPPG--GGAC-----------------------LCDPVTGACPCLPNVTGLACDR- 1063
EC PG G C C P+ G+C C P G C +
Sbjct: 639 --CECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQA 696
Query: 1064 CADGYWNLVPGRGC-QSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSE-CQENYYGDP 1121
C G+W G C +C C + C G C C G+ G C++ C ++G
Sbjct: 697 CPPGFW----GPACFHACSC----HNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKD 748
Query: 1122 PGRCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCD-RCARG 1164
GR C C + CD +G C CR G +GQ C+ RCA G
Sbjct: 749 CGRV--CQCQNGAS----CDHISGKCTCRTGFTGQHCEQRCAPG 786
Score = 136 bits (343), Expect = 2e-31
Identities = 117/376 (31%), Positives = 149/376 (39%), Gaps = 75/376 (19%)
Query: 801 RCSTGSYDLGHHGCHPCHCHPQGSKDTVCDQVTGQCPCHGEVS--GRRCDR-CLAGYFGF 857
+C G Y+ G C P +++ V + CH E G C C + ++G
Sbjct: 87 QCCPGYYESGDF------CIPLCTEECVHGRCVSPDTCHCEPGWGGPDCSSGCDSDHWGP 140
Query: 858 PSCHPCPCNRFAELCDPETGSCFNCGGFTTGRNCERCIDGYYGNPSSGQPCR-PCLCPDD 916
+ C C A LC+P TG+C GF R E C G + G+ C+ PC C
Sbjct: 141 HCSNRCQCQNGA-LCNPITGACVCAAGFRGWRCEELCAPG-----THGKGCQLPCQCRHG 194
Query: 917 PSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGE-CSTGFYGNPRISGAPCQ-PCACNN 974
S + C C GYTG C E C G + GA C+ C C N
Sbjct: 195 ASCDPRAGE------------CLCAPGYTGVYCEELCPPGSH------GAHCELRCPCQN 236
Query: 975 NIDVTDPESCSRVTGECLRCLHNTQGANC-QLCKPGHYGSALNQTCRRCSCHASGVSPME 1033
+C +TGEC C GA C Q C PG +G +Q C CH G
Sbjct: 237 G------GTCHHITGEC-ACPPGWTGAVCAQPCPPGTFGQNCSQD---CPCHHGG----- 281
Query: 1034 CPPGGGACLCDPVTGACPCLPNVTGLAC-DRCADGYWNLVPGRGCQSCDCDPRTSQSSHC 1092
CD VTG C C G C + C G + + Q CDC C
Sbjct: 282 --------QCDHVTGQCHCTAGYMGDRCQEECPFGSFGF---QCSQHCDC----HNGGQC 326
Query: 1093 DQLTGQCPCKLGYGGKRCSE--CQENYYGDPPGRCIPCDCNRAGTQKPICDPDTGMCRCR 1150
TG C C+ GY G RC E C E +G PG +PC C+ T C P TG C C+
Sbjct: 327 SPTTGACECEPGYKGPRCQERLCPEGLHG--PGCTLPCPCDADNTIS--CHPVTGACTCQ 382
Query: 1151 EGVSGQRC-DRCARGH 1165
G SG C + C G+
Sbjct: 383 PGWSGHHCNESCPVGY 398
Score = 113 bits (282), Expect = 2e-24
Identities = 94/310 (30%), Positives = 115/310 (37%), Gaps = 68/310 (21%)
Query: 886 TTGRNCERCIDGYYGNPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYT 945
T R +C GYY SG C P LC ++ C S C+C G+
Sbjct: 80 TMYRRRSQCCPGYY---ESGDFCIP-LCTEE----------CVHGRCVSPDTCHCEPGWG 125
Query: 946 GTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQ- 1004
G C + P S C C N C+ +TG C+ C +G C+
Sbjct: 126 GPDCSSGCDSDHWGPHCSNR----CQCQNGA------LCNPITGACV-CAAGFRGWRCEE 174
Query: 1005 LCKPGHYGSALNQTCR------------RCSCHA--SGVSPME-CPPG--GGAC------ 1041
LC PG +G C+ C C +GV E CPPG G C
Sbjct: 175 LCAPGTHGKGCQLPCQCRHGASCDPRAGECLCAPGYTGVYCEELCPPGSHGAHCELRCPC 234
Query: 1042 ----LCDPVTGACPCLPNVTGLACDRCADGYWNLVPGRGCQSCDCDPRTSQSSHCDQLTG 1097
C +TG C C P TG C + PG Q+C D CD +TG
Sbjct: 235 QNGGTCHHITGECACPPGWTGAVCAQPCP------PGTFGQNCSQDCPCHHGGQCDHVTG 288
Query: 1098 QCPCKLGYGGKRCSECQENYYGDPPGRCIP-CDCNRAGTQKPICDPDTGMCRCREGVSGQ 1156
QC C GY G RC E E +G +C CDC+ G C P TG C C G G
Sbjct: 289 QCHCTAGYMGDRCQE--ECPFGSFGFQCSQHCDCHNGGQ----CSPTTGACECEPGYKGP 342
Query: 1157 RCDR--CARG 1164
RC C G
Sbjct: 343 RCQERLCPEG 352
Score = 92.0 bits (227), Expect = 4e-18
Identities = 85/289 (29%), Positives = 107/289 (37%), Gaps = 50/289 (17%)
Query: 272 SECRPMQKMRGDVFSP---PGMVHGQCV------CQHNTDGPNCERCKDFFQDAPWRPAA 322
S+C P GD P VHG+CV C+ GP+C D W P
Sbjct: 86 SQCCPGYYESGDFCIPLCTEECVHGRCVSPDTCHCEPGWGGPDCSSGCD---SDHWGPHC 142
Query: 323 DLQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCED-CQHNTEGQHCD---RCRPLF 378
+ CN + C + + G G CE+ C T G+ C +CR
Sbjct: 143 SNRCQCQNGALCNPITGAC-------VCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGA 195
Query: 379 YRDPLK---TISDPYACIPCE--CDPD--GTISGGICVSHSDPALGSVAGQCLCKENVEG 431
DP + Y + CE C P G C + + G+C C G
Sbjct: 196 SCDPRAGECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTG 255
Query: 432 AKCDQ-CKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHC-EEC 489
A C Q C P +G + + Q C C+ G CD TGQC C + G C EEC
Sbjct: 256 AVCAQPCPPGTFGQNCS-----QDCPCHHGGQ-----CDHVTGQCHCTAGYMGDRCQEEC 305
Query: 490 TVGYWGLGNHLHGCSPCDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSE 538
G +G H CDC GG CSP G CEC P G C E
Sbjct: 306 PFGSFGFQCSQH----CDCHNGGQ----CSPTTGACECEPGYKGPRCQE 346
Score = 86.3 bits (212), Expect = 2e-16
Identities = 76/270 (28%), Positives = 97/270 (35%), Gaps = 43/270 (15%)
Query: 291 VHGQCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACR-SCSCNSHSSRCHFDMTTYL 349
+ G CVC G CE A C+ C C H + C L
Sbjct: 157 ITGACVCAAGFRGWRCEELC----------APGTHGKGCQLPCQCR-HGASCDPRAGECL 205
Query: 350 ASGGLSGGVCED-CQHNTEGQHCDRCRPLFYRDPLKTISDPYACIP-------CECDPDG 401
+ G +G CE+ C + G HC+ P I+ AC P + P G
Sbjct: 206 CAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCAQPCPPG 265
Query: 402 TISGGI---CVSHSDPALGSVAGQCLCKENVEGAKC-DQCKPNHYGLSATDPLGCQPCDC 457
T C H V GQC C G +C ++C +G + Q CDC
Sbjct: 266 TFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCS-----QHCDC 320
Query: 458 NPLGSLPFLTCDVDTGQCLCLSYVTGAHCEE--CTVGYWGLGNHLHGCSPCDCDIGGAYS 515
+ G C TG C C G C+E C G G G L PC CD S
Sbjct: 321 HNGGQ-----CSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTL----PCPCDADNTIS 371
Query: 516 NVCSPKNGQCECRPHVTGRSCSEPAP-GYF 544
C P G C C+P +G C+E P GY+
Sbjct: 372 --CHPVTGACTCQPGWSGHHCNESCPVGYY 399
Score = 81.3 bits (199), Expect = 8e-15
Identities = 78/293 (26%), Positives = 96/293 (32%), Gaps = 91/293 (31%)
Query: 291 VHGQCVCQHNTDGPNC-ERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYL 349
V G C CQ G +C E C P D C+C + + CH
Sbjct: 375 VTGACTCQPGWSGHHCNESC----------PVGYYGDGCQLPCTCQNGAD-CHSITGGCT 423
Query: 350 ASGGLSGGVCE-DCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGIC 408
+ G G VC C T G +C C C+ GT S
Sbjct: 424 CAPGFMGEVCAVSCAAGTYGPNCSSI--------------------CSCNNGGTCS---- 459
Query: 409 VSHSDPALGSVAGQCLCKENVEGAKCD-QCKPNHYGLSATDPLGCQ----------PCDC 457
V G C CKE +G C C +GL+ + C C C
Sbjct: 460 ---------PVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSC 510
Query: 458 NP--LGSLPFLT---------------------CDVDTGQCLCLSYVTGAHCEE-CTVGY 493
P LG L CD TG C CL+ TG C+ C G
Sbjct: 511 TPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGR 570
Query: 494 WGLGNHLHGCS-PCDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPAPGYFF 545
WG CS C C+ GG+ CSP++G CEC P G C P F+
Sbjct: 571 WG-----PNCSVSCSCENGGS----CSPEDGSCECAPGFRGPLCQRICPPGFY 614
Score = 81.3 bits (199), Expect = 8e-15
Identities = 85/305 (27%), Positives = 114/305 (37%), Gaps = 49/305 (16%)
Query: 264 SCFCNGHASECRPMQKMR-GDVFSPPGMVHGQCVCQHNTDGPNCER-CKDFFQDAPWRPA 321
SC + C + G SP V G C C+ G +C C P+
Sbjct: 436 SCAAGTYGPNCSSICSCNNGGTCSP---VDGSCTCKEGWQGLDCTLPC----------PS 482
Query: 322 ADLQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCE-DCQHNTEGQHCDRCRPLFYR 380
N SC+C + ++ D + G L G CE C T G +C +
Sbjct: 483 GTWGLNCNESCTCANGAACSPIDGSCSCTPGWL-GDTCELPCPDGTFGLNCSEHCDCSHA 541
Query: 381 DPLKTISDPYACIP----CECD---PDGTISGGICVSHSDPALGSVA---GQCLCKENVE 430
D ++ C+ CD P G VS S GS + G C C
Sbjct: 542 DGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFR 601
Query: 431 GAKCDQ-CKPNHYGLSATDPLGC-QPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEE 488
G C + C P YG GC QPC S P C +G C CL +GA C +
Sbjct: 602 GPLCQRICPPGFYGH------GCAQPCPLCVHSSRP---CHHISGICECLPGFSGALCNQ 652
Query: 489 -CTVGYWGLGNHLHGCSP-CDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPAPGYFFA 546
C GY+G C+ C C A + CSP +G C+C P G+ CS+ P F+
Sbjct: 653 VCAGGYFG-----QDCAQLCSC----ANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFWG 703
Query: 547 PLNFY 551
P F+
Sbjct: 704 PACFH 708
Score = 75.9 bits (185), Expect = 3e-13
Identities = 73/298 (24%), Positives = 99/298 (33%), Gaps = 44/298 (14%)
Query: 265 CFCNGHASECR-PMQKMRGDVFSPPGMVHGQCVCQHNTDGPNCERCKDFFQDAPWRPAAD 323
C H C+ P Q G P G+C+C G CE P
Sbjct: 176 CAPGTHGKGCQLPCQCRHGASCDPRA---GECLCAPGYTGVYCEELC---------PPGS 223
Query: 324 LQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVC-EDCQHNTEGQHCDRCRPLFYRDP 382
+ C C + + CH G +G VC + C T GQ+C + P +
Sbjct: 224 HGAHCELRCPCQNGGT-CHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQ 282
Query: 383 LKTISDPYACIP----------CECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGA 432
++ C C G C H+ G C C+ +G
Sbjct: 283 CDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGACECEPGYKGP 342
Query: 433 KCDQ--CKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEE-C 489
+C + C +G T P PCD + ++C TG C C +G HC E C
Sbjct: 343 RCQERLCPEGLHGPGCTLPC---PCDADNT-----ISCHPVTGACTCQPGWSGHHCNESC 394
Query: 490 TVGYWGLGNHLHGCSPCDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPAPGYFFAP 547
VGY+G G L PC C G C G C C P G C+ + P
Sbjct: 395 PVGYYGDGCQL----PCTCQNGAD----CHSITGGCTCAPGFMGEVCAVSCAAGTYGP 444
Score = 74.7 bits (182), Expect = 7e-13
Identities = 48/150 (32%), Positives = 61/150 (40%), Gaps = 22/150 (14%)
Query: 395 CECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQ-CKPNHYGLSATDPLGCQ 453
C+ D G C + + G C+C G +C++ C P +G GCQ
Sbjct: 133 CDSDHWGPHCSNRCQCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGK------GCQ 186
Query: 454 -PCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEE-CTVGYWGLGNHLHGCSPCDCDIG 511
PC C S CD G+CLC TG +CEE C G G L C C G
Sbjct: 187 LPCQCRHGAS-----CDPRAGECLCAPGYTGVYCEELCPPGSHGAHCELR----CPCQNG 237
Query: 512 GAYSNVCSPKNGQCECRPHVTGRSCSEPAP 541
G C G+C C P TG C++P P
Sbjct: 238 G----TCHHITGECACPPGWTGAVCAQPCP 263
Score = 73.9 bits (180), Expect = 1e-12
Identities = 81/285 (28%), Positives = 97/285 (34%), Gaps = 79/285 (27%)
Query: 265 CFCNGHASECRPMQKMRGDVFSPPGMVHGQCVCQHNTDGPNCERCKDFFQDAPWRPAADL 324
C C+ HA C P V G C C G RC W P
Sbjct: 536 CDCS-HADGCDP--------------VTGHCCCLAGWTGI---RCDSTCPPGRWGP---- 573
Query: 325 QDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDR-CRPLFYRDPL 383
N SCSC + S D G CE C G C R C P FY
Sbjct: 574 --NCSVSCSCENGGSCSPED------------GSCE-CAPGFRGPLCQRICPPGFYG--- 615
Query: 384 KTISDPYACI-PCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQ-CKPNH 441
+ C PC +CV HS ++G C C GA C+Q C +
Sbjct: 616 ------HGCAQPCP----------LCV-HSSRPCHHISGICECLPGFSGALCNQVCAGGY 658
Query: 442 YGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEE-CTVGYWGLGNHL 500
+G Q C C G TC G C C G C + C G+WG
Sbjct: 659 FGQDCA-----QLCSCANNG-----TCSPIDGSCQCFPGWIGKDCSQACPPGFWGPAC-F 707
Query: 501 HGCSPCDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPAPGYFF 545
H CS C G + CS ++G C C P TG C++ P FF
Sbjct: 708 HACS---CHNGAS----CSAEDGACHCTPGWTGLFCTQRCPAAFF 745
Score = 67.0 bits (162), Expect = 2e-10
Identities = 68/263 (25%), Positives = 87/263 (33%), Gaps = 43/263 (16%)
Query: 293 GQCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSR-CHFDMTTYLAS 351
G C C GP C+R P + C HSSR CH
Sbjct: 592 GSCECAPGFRGPLCQRIC---------PPGFYGHGCAQPCPLCVHSSRPCHHISGICECL 642
Query: 352 GGLSGGVCED-CQHNTEGQHCDRCRPLFYRDPLKTISDPYACIP------CE--CDPD-- 400
G SG +C C GQ C + I C P C C P
Sbjct: 643 PGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFW 702
Query: 401 GTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQ-CKPNHYGLSATDPLGCQPCDCNP 459
G C H+ + + G C C G C Q C +G + C C
Sbjct: 703 GPACFHACSCHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCG-----RVCQCQN 757
Query: 460 LGSLPFLTCDVDTGQCLCLSYVTGAHCEE-CTVGYWGLGNHLHGCSP-CDCDIGGAYSNV 517
S CD +G+C C + TG HCE+ C G +G +GC C+C ++
Sbjct: 758 GAS-----CDHISGKCTCRTGFTGQHCEQRCAPGTFG-----YGCQQLCEC----MNNST 803
Query: 518 CSPKNGQCECRPHVTGRSCSEPA 540
C G C C P G C + A
Sbjct: 804 CDHVTGTCYCSPGFKGIRCDQAA 826
Score = 50.8 bits (120), Expect = 1e-05
Identities = 46/205 (22%), Positives = 67/205 (32%), Gaps = 59/205 (28%)
Query: 291 VHGQCVCQHNTDGPNCER-CKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYL 349
+ G C C G +C + C F W PA + SC++ CH
Sbjct: 678 IDGSCQCFPGWIGKDCSQACPPGF----WGPACFHACSCHNGASCSAEDGACH------- 726
Query: 350 ASGGLSGGVCEDCQHNTEGQHC-DRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGIC 408
C G C RC F+ G G +C
Sbjct: 727 ------------CTPGWTGLFCTQRCPAAFF---------------------GKDCGRVC 753
Query: 409 VSHSDPALGSVAGQCLCKENVEGAKCDQ-CKPNHYGLSATDPLGCQP-CDCNPLGSLPFL 466
+ + ++G+C C+ G C+Q C P +G GCQ C+C +
Sbjct: 754 QCQNGASCDHISGKCTCRTGFTGQHCEQRCAPGTFGY------GCQQLCEC-----MNNS 802
Query: 467 TCDVDTGQCLCLSYVTGAHCEECTV 491
TCD TG C C G C++ +
Sbjct: 803 TCDHVTGTCYCSPGFKGIRCDQAAL 827
>gi|190014607 netrin G2 [Homo sapiens]
Length = 530
Score = 167 bits (423), Expect = 8e-41
Identities = 116/392 (29%), Positives = 180/392 (45%), Gaps = 72/392 (18%)
Query: 129 LILTFKTFRPAAMLVERSTDYGHNWKVFKYFAKDCATSFPNITSGQAQGVGD-----IVC 183
+++TF+ RP M++E+S D G W+ ++++A+DC +F +++ +A+ + ++C
Sbjct: 137 VVMTFEYGRPTVMVLEKSLDNGRTWQPYQFYAEDCMEAF-GMSARRARDMSSSSAHRVLC 195
Query: 184 DSKYSDIEPSTGGEVVLKVLDPSFEI---------ENPYSPY-----IQDLVTLTNLRIN 229
+YS S + V + F I +N Y+ +++ TLT+LR+
Sbjct: 196 TEEYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRLESAKGLKEFFTLTDLRMR 255
Query: 230 FTKLHTLGDALLGRRQNDSLDKYYYALYEMIVRGSCFCNGHASECRPMQKMRGDVFSPPG 289
+ LG + Q ++L KY+YA+ + V G C CN HA+ C + G +
Sbjct: 256 LLR-PALGGTYV---QRENLYKYFYAISNIEVIGRCKCNLHANLCSMRE---GSL----- 303
Query: 290 MVHGQCVCQHNTDGPNCERCKDFFQDAPWRPAADL-----QDNACRS------CSCNSHS 338
QC C+HNT GP+C +CK F+ WR + L NAC + C C HS
Sbjct: 304 ----QCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHS 359
Query: 339 SRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECD 398
+RC + L+ C C+HNT GQHC CR +YR+ + D CI C C+
Sbjct: 360 NRCSY-------IDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCN 412
Query: 399 PDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQP--CD 456
G++ + G C C+E G KCD C P HY GC P CD
Sbjct: 413 QIGSVHDRC----------NETGFCECREGAAGPKCDDCLPTHYWRQ-----GCYPNVCD 457
Query: 457 CNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEE 488
+ L TC + +C C TG CE+
Sbjct: 458 DDQLLCQNGGTC-LQNQRCACPRGYTGVRCEQ 488
Score = 76.3 bits (186), Expect = 3e-13
Identities = 63/221 (28%), Positives = 87/221 (39%), Gaps = 31/221 (14%)
Query: 332 CSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISD--- 388
C CN H++ C + G L CE C+HNT G C +C+ F + S
Sbjct: 287 CKCNLHANLCS------MREGSLQ---CE-CEHNTTGPDCGKCKKNFRTRSWRAGSYLPL 336
Query: 389 PYACIPCECDPDGTISGGICVSHSDPA----LGSVAGQCLCKENVEGAKCDQCKPNHY-- 442
P+ P C G+ C HS+ +V CK N G C C+ +Y
Sbjct: 337 PHGS-PNACATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRN 395
Query: 443 -GLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECT-VGYWGLGNHL 500
D C C+CN +GS+ C+ +TG C C G C++C YW
Sbjct: 396 GSAELDDENVCIECNCNQIGSVHD-RCN-ETGFCECREGAAGPKCDDCLPTHYWR----- 448
Query: 501 HGCSP--CDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEP 539
GC P CD D + +N +C C TG C +P
Sbjct: 449 QGCYPNVCDDDQLLCQNGGTCLQNQRCACPRGYTGVRCEQP 489
Score = 74.3 bits (181), Expect = 1e-12
Identities = 64/224 (28%), Positives = 83/224 (37%), Gaps = 41/224 (18%)
Query: 938 CNCLQGYTGTQCGECSTGFYGN--------PRISGAP--CQPCACNNNIDVTDPES-CSR 986
C C TG CG+C F P G+P C N + + CS
Sbjct: 305 CECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCSY 364
Query: 987 V----TGECLRCLHNTQGANCQLCKPGHY--GSAL---NQTCRRCSCHASGVSPMECPPG 1037
+ C+ C HNT+G +CQ C+ G+Y GSA C C+C+ G C
Sbjct: 365 IDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNE- 423
Query: 1038 GGACLCDPVTGACPCLPNVTGLACDRC-ADGYWNLVPGRGC--QSCDCDPRTSQSSHCDQ 1094
TG C C G CD C YW +GC CD D Q+
Sbjct: 424 ---------TGFCECREGAAGPKCDDCLPTHYWR----QGCYPNVCDDDQLLCQNGGTCL 470
Query: 1095 LTGQCPCKLGYGGKRCSECQENYYGDPPGRCIPCDCNRAGTQKP 1138
+C C GY G RC + + + D G DC+RA P
Sbjct: 471 QNQRCACPRGYTGVRCEQPRCDPADDDGG----LDCDRAPGAAP 510
Score = 69.3 bits (168), Expect = 3e-11
Identities = 59/198 (29%), Positives = 80/198 (40%), Gaps = 41/198 (20%)
Query: 970 CACNNNIDVTDPESCSRVTGEC-LRCLHNTQGANCQLCKPGHYGSALNQTCRRCSCHASG 1028
C CN + ++ CS G C HNT G +C CK + R S A
Sbjct: 287 CKCNLHANL-----CSMREGSLQCECEHNTTGPDCGKCK---------KNFRTRSWRAGS 332
Query: 1029 VSPMECPPGG-GACLCDPVTGACPCLPNVTGLACDRCADGYWNLVPGRGCQSCDCDPRTS 1087
P+ P G AC G C C + +RC+ Y + + C SC + R
Sbjct: 333 YLPL--PHGSPNACATAGSFGNCECYGH-----SNRCS--YIDFLNVVTCVSCKHNTR-- 381
Query: 1088 QSSHCDQLTGQCPCKLGYGGKRCSECQENYYGDPPGRCIPCDCNRAGTQKPICDPDTGMC 1147
HC C+LGY +E D CI C+CN+ G+ C+ +TG C
Sbjct: 382 -GQHCQH------CRLGYYRNGSAEL------DDENVCIECNCNQIGSVHDRCN-ETGFC 427
Query: 1148 RCREGVSGQRCDRCARGH 1165
CREG +G +CD C H
Sbjct: 428 ECREGAAGPKCDDCLPTH 445
Score = 65.1 bits (157), Expect = 6e-10
Identities = 59/214 (27%), Positives = 80/214 (37%), Gaps = 47/214 (21%)
Query: 769 CKCHPQGSVGSSCSRLGG--QCQCKPLVVGRCCDRCS---------TGSYDLGHHGC--- 814
CKC+ ++ CS G QC+C+ G C +C GSY HG
Sbjct: 287 CKCNLHANL---CSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNA 343
Query: 815 -------HPCHCHPQGSKDTVCD--QVTGQCPCHGEVSGRRCDRCLAGYFGFPS------ 859
C C+ ++ + D V C G+ C C GY+ S
Sbjct: 344 CATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDE 403
Query: 860 --CHPCPCNRFAELCD--PETGSCFNCGGFTTGRNCERCIDGYYGNPSSGQPCRPCLCPD 915
C C CN+ + D ETG C C G C+ C+ +Y Q C P +C D
Sbjct: 404 NVCIECNCNQIGSVHDRCNETGFC-ECREGAAGPKCDDCLPTHYWR----QGCYPNVCDD 458
Query: 916 DPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQC 949
D Q +C QN C C +GYTG +C
Sbjct: 459 DQLLCQN-GGTCLQN-----QRCACPRGYTGVRC 486
Score = 56.6 bits (135), Expect = 2e-07
Identities = 38/146 (26%), Positives = 60/146 (41%), Gaps = 24/146 (16%)
Query: 422 QCLCKENVEGAKCDQCKPN------HYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQC 475
QC C+ N G C +CK N G P G P C GS C + +C
Sbjct: 304 QCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHG-SPNACATAGSFGNCECYGHSNRC 362
Query: 476 LCLSYVT------------GAHCEECTVGYWGLG----NHLHGCSPCDCDIGGAYSNVCS 519
+ ++ G HC+ C +GY+ G + + C C+C+ G+ + C+
Sbjct: 363 SYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCN 422
Query: 520 PKNGQCECRPHVTGRSCSEPAPGYFF 545
+ G CECR G C + P +++
Sbjct: 423 -ETGFCECREGAAGPKCDDCLPTHYW 447
Score = 55.8 bits (133), Expect = 4e-07
Identities = 37/127 (29%), Positives = 51/127 (40%), Gaps = 15/127 (11%)
Query: 790 CKPLVVGRCCDRCSTGSYDLG------HHGCHPCHCHPQGSKDTVCDQVTGQCPCHGEVS 843
CK G+ C C G Y G + C C+C+ GS C++ TG C C +
Sbjct: 376 CKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNE-TGFCECREGAA 434
Query: 844 GRRCDRCLAGYFGFPSCHPCPCNRFAELCDPETGSCFNCGGFTTGRNCERCIDGYYGNPS 903
G +CD CL ++ C+P +CD + C N G + C C GY G
Sbjct: 435 GPKCDDCLPTHYWRQGCYP-------NVCDDDQLLCQNGGTCLQNQRC-ACPRGYTGVRC 486
Query: 904 SGQPCRP 910
C P
Sbjct: 487 EQPRCDP 493
Score = 42.4 bits (98), Expect = 0.004
Identities = 36/110 (32%), Positives = 45/110 (40%), Gaps = 19/110 (17%)
Query: 759 SAKLHDGAVA--CKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHGCHP 816
SA+L D V C C+ GSV C+ G C+C+ G CD C Y GC+P
Sbjct: 397 SAELDDENVCIECNCNQIGSVHDRCNETGF-CECREGAAGPKCDDCLPTHY--WRQGCYP 453
Query: 817 CHCHPQGSKDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGF----PSCHP 862
C D + Q G C + +RC C GY G P C P
Sbjct: 454 NVC----DDDQLLCQNGGTC-----LQNQRC-ACPRGYTGVRCEQPRCDP 493
>gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens]
Length = 1823
Score = 166 bits (419), Expect = 2e-40
Identities = 92/240 (38%), Positives = 125/240 (52%), Gaps = 40/240 (16%)
Query: 848 DRCLAGYFGFPS--CHPCPCNRFAELCDPETGSCFNCGGFTTGRNCERCIDGYYGNPSSG 905
++C AG+F S C PC CN + C +G C +C TTG +CE+C+DGY G+ G
Sbjct: 65 EKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRG 124
Query: 906 QP--CRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRIS 963
P C+PC CP +N FA SCY+ + V C C + Y G C C+ G+YGNP +
Sbjct: 125 APQFCQPCPCPLPHLAN--FAESCYRK--NGAVRCICNENYAGPNCERCAPGYYGNPLLI 180
Query: 964 GAPCQPCACNNNIDVTDP----ESCSRVTGECLRCLHNTQGANCQLCKPGHYGSA-LNQT 1018
G+ C+ C C+ N +DP E C VTG+C CL NT G C+ C PG+YG A + +
Sbjct: 181 GSTCKKCDCSGN---SDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKN 237
Query: 1019 CRRCSCHASGVSPMECPPGGGACLCDPVTGAC-------PCLPNVTGLACDRCADGYWNL 1071
C C+C GGG CD VTG C P + ++CD+C W+L
Sbjct: 238 CAVCNC------------GGGP--CDSVTGECLEEGFEPPTGMDCPTISCDKCV---WDL 280
Score = 109 bits (273), Expect = 2e-23
Identities = 66/201 (32%), Positives = 88/201 (43%), Gaps = 28/201 (13%)
Query: 329 CRSCSCNSHSSRCHFDMTTYLASGGLSG-GVCEDCQHNTEGQHCDRCRPLFYRDPLKTIS 387
C C CN +S+ C L G G C CQ NT G+HC++C + D ++
Sbjct: 79 CVPCDCNGNSNEC------------LDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIR--G 124
Query: 388 DPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSAT 447
P C PC C + + A+ +C+C EN G C++C P +YG
Sbjct: 125 APQFCQPCPCPLPHLANFAESCYRKNGAV-----RCICNENYAGPNCERCAPGYYGNPLL 179
Query: 448 DPLGCQPCDC--NPLGSLPFLTCDVDTGQCL-CLSYVTGAHCEECTVGYWGLGNHLHGCS 504
C+ CDC N +L F CD TGQC CL TG CE C GY+G C+
Sbjct: 180 IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCA 239
Query: 505 PCDCDIGGAYSNVCSPKNGQC 525
C+C GG C G+C
Sbjct: 240 VCNC--GG---GPCDSVTGEC 255
Score = 90.5 bits (223), Expect = 1e-17
Identities = 61/192 (31%), Positives = 78/192 (40%), Gaps = 25/192 (13%)
Query: 747 LPGACERLIISMSAKLHDGAVACKCHPQGSVGSSCSRLGGQC-QCKPLVVGRCCDRCSTG 805
LP A E+ L V C C+ + C G C C+ G C++C G
Sbjct: 60 LPPAAEKCNAGFFHTLSGECVPCDCNGNSN---ECLDGSGYCVHCQRNTTGEHCEKCLDG 116
Query: 806 SYDLGHHG----CHPCHC---HPQGSKDTVCDQVTG--QCPCHGEVSGRRCDRCLAGYFG 856
G C PC C H ++ C + G +C C+ +G C+RC GY+G
Sbjct: 117 YIGDSIRGAPQFCQPCPCPLPHLANFAES-CYRKNGAVRCICNENYAGPNCERCAPGYYG 175
Query: 857 FP-----SCHPCPC------NRFAELCDPETGSCFNCGGFTTGRNCERCIDGYYGNPSSG 905
P +C C C N E CD TG C NC TTG CERC GYYG+
Sbjct: 176 NPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIA 235
Query: 906 QPCRPCLCPDDP 917
+ C C C P
Sbjct: 236 KNCAVCNCGGGP 247
Score = 89.0 bits (219), Expect = 4e-17
Identities = 154/794 (19%), Positives = 308/794 (38%), Gaps = 99/794 (12%)
Query: 1006 CKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCA 1065
C G + + L+ C C C+ + EC G G C+ C N TG C++C
Sbjct: 67 CNAGFFHT-LSGECVPCDCNGNS---NECLDGSGYCV--------HCQRNTTGEHCEKCL 114
Query: 1066 DGY-WNLVPG--RGCQSCDCD-PRTSQ-SSHCDQLTG--QCPCKLGYGGKRCSECQENYY 1118
DGY + + G + CQ C C P + + C + G +C C Y G C C YY
Sbjct: 115 DGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174
Query: 1119 GDP---PGRCIPCDCNRAGTQKPI---CDPDTGMCR-CREGVSGQRCDRCARGHSQEFPT 1171
G+P C CDC+ I CD TG CR C +G +C+RCA G+ +
Sbjct: 175 GNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARI 234
Query: 1172 CLQCHLCFDQWDHTISSLSKAVQGLMRLAANMEDKRETLPVCEADFKD-LRGNVSEIERI 1230
C +C S + ++ M+ + C D D LR IE
Sbjct: 235 AKNCAVCNCGGGPCDSVTGECLEEGFEPPTGMDCPTISCDKCVWDLTDALRLAALSIEE- 293
Query: 1231 LKHPVFPSGKFLKVKDYHDSVRRQIMQLNEQL-KAVYEFQDLKDTIERAKNEADLLLEDL 1289
K V + + + I L +L + ++ K I A+N LL D+
Sbjct: 294 GKSGVLSVSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDV 353
Query: 1290 QEEIDLQSSVLNASIADSSENIKKYYHISSSAEK------KINETSSTINTSANTRNDLL 1343
+E ++ ++ E++ H S E+ KI E ++ + ++L
Sbjct: 354 EELVEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKM-LYYGEEHELS 412
Query: 1344 TILDTLTSKGNLSLERLKQIKIPDIQILNEKVCGDPGNVPCVPLPCGGALCTGRKGHRKC 1403
++ K L+ + L++I+ ++ + + L + ++ H +
Sbjct: 413 P--KEISEKLVLAQKMLEEIRSRQPFFTQRELVDEEADEAYELL---SQAESWQRLHNET 467
Query: 1404 RGPGCHGSLTLSTNALQKAQEAKSIIRNLDKQVRGLKNQIESISEQAEVSKNNALQLREK 1463
R TL L++ + + + +L + + N + + + ++
Sbjct: 468 R--------TLFPVVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQ 519
Query: 1464 LGNIRNQSDSEEENINLFIKKVKNFLLEENVPPEDIEKVANGVLDIHLPIPS-------- 1515
+R Q E +N+ + + L + +++ + I+ I
Sbjct: 520 QERVREQM----EVVNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVK 575
Query: 1516 ----QNLTDELVKIQKHMQLCEDYRTDENRLNEEADGAQKLLVKAKAAEKAANILLNLDK 1571
NL+ +LV Q+ + +D + + N L+ + + + KA + A+N+ N+
Sbjct: 576 LSNLSNLSHDLV--QEAIDHAQDLQQEANELSRKLHSSDMNGLVQKALD-ASNVYENI-- 630
Query: 1572 TLNQLQQAQITQGRANSTITQLTANITKIKKNVLQAENQTREMKSELELAKQRSGLEDGL 1631
+N + +A T A +T ++ ++ I ++ ++++ + L A++
Sbjct: 631 -VNYVSEANETAEFALNTTDRIYDAVSGIDTQIIYHKDESENL---LNQARE-------- 678
Query: 1632 SLLQTKLQRHQDHAVNAKVQAESAQHQAGSL-EKEFVELKKQYAILQRKTSTTGLTKETL 1690
LQ K + D AV A++++ G+L K ++ + A+ Q + + G ++ L
Sbjct: 679 --LQAKAESSSDEAV-----ADTSRRVGGALARKSALKTRLSDAVKQLQAAERGDAQQRL 731
Query: 1691 GKVKQLKDAAEKLAGD----TEAKIRRITDLERKIQDL-----NLSRQAKADQLRILEDQ 1741
G+ + + + A + + T +T+ + +Q N + + D +R L +
Sbjct: 732 GQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNSARDAVRNLTEV 791
Query: 1742 VVAIKNEIVEQEKK 1755
V + +++ E+K
Sbjct: 792 VPQLLDQLRTVEQK 805
Score = 87.8 bits (216), Expect = 8e-17
Identities = 78/247 (31%), Positives = 103/247 (41%), Gaps = 55/247 (22%)
Query: 265 CFCNGHASECRPMQKMRGDVFSPPGMVHGQCV-CQHNTDGPNCERCKDFFQDAPWRPAAD 323
C CNG+++EC + G G CV CQ NT G +CE+C D + R A
Sbjct: 82 CDCNGNSNEC-----LDGS---------GYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQ 127
Query: 324 LQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPL 383
C+ C C +F + Y +G + C C N G +C+RC P +Y +PL
Sbjct: 128 F----CQPCPC-PLPHLANFAESCYRKNGAVR---C-ICNENYAGPNCERCAPGYYGNPL 178
Query: 384 KTISDPYACIPCECDPDGTISGGICVSHSDPAL-----GSVAGQCL-CKENVEGAKCDQC 437
S C C+C +SDP L V GQC C N G KC++C
Sbjct: 179 LIGS---TCKKCDCS-----------GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERC 224
Query: 438 KPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSY--VTGAHCE--ECTVGY 493
P +YG A C C+C G P CD TG+CL + TG C C
Sbjct: 225 APGYYG-DARIAKNCAVCNC---GGGP---CDSVTGECLEEGFEPPTGMDCPTISCDKCV 277
Query: 494 WGLGNHL 500
W L + L
Sbjct: 278 WDLTDAL 284
Score = 75.1 bits (183), Expect = 6e-13
Identities = 55/167 (32%), Positives = 75/167 (44%), Gaps = 30/167 (17%)
Query: 392 CIPCECDPDGTISGGICVSHSDPALGSVAGQCL-CKENVEGAKCDQCKPNHYGLSATD-P 449
C+PC+C+ +S+ L +G C+ C+ N G C++C + G S P
Sbjct: 79 CVPCDCN-----------GNSNECLDG-SGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAP 126
Query: 450 LGCQPCDCNPLGSLPFL--TCDVDTG--QCLCLSYVTGAHCEECTVGYWGLGNHL---HG 502
CQPC C PL L +C G +C+C G +CE C GY+G N L
Sbjct: 127 QFCQPCPC-PLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYG--NPLLIGST 183
Query: 503 CSPCDCDIGGAYSNV----CSPKNGQCE-CRPHVTGRSCSEPAPGYF 544
C CDC G + N+ C GQC C + TG C APGY+
Sbjct: 184 CKKCDCS-GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYY 229
Score = 67.0 bits (162), Expect = 2e-10
Identities = 49/155 (31%), Positives = 65/155 (41%), Gaps = 21/155 (13%)
Query: 403 ISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGS 462
I G V DP S L + KC+ G T C PCDCN +
Sbjct: 36 IEGSSAVGRQDPPETSEPRVALGRLPPAAEKCNA------GFFHTLSGECVPCDCNGNSN 89
Query: 463 LPFLTCDVDTGQCL-CLSYVTGAHCEECTVGYWGLGNHLHG----CSPCDCDIG--GAYS 515
C +G C+ C TG HCE+C GY +G+ + G C PC C + ++
Sbjct: 90 ----ECLDGSGYCVHCQRNTTGEHCEKCLDGY--IGDSIRGAPQFCQPCPCPLPHLANFA 143
Query: 516 NVCSPKNG--QCECRPHVTGRSCSEPAPGYFFAPL 548
C KNG +C C + G +C APGY+ PL
Sbjct: 144 ESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPL 178
Score = 64.3 bits (155), Expect = 1e-09
Identities = 51/191 (26%), Positives = 71/191 (37%), Gaps = 39/191 (20%)
Query: 294 QCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASGG 353
+C+C N GPNCERC + P L + C+ C C+ +S D
Sbjct: 154 RCICNENYAGPNCERCAPGYYGNPL-----LIGSTCKKCDCSGNS-----DPNLIFEDCD 203
Query: 354 LSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSHSD 413
G C +C NT G C+RC P +Y D + C C C GG C
Sbjct: 204 EVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKN----CAVCNC------GGGPC----- 248
Query: 414 PALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTG 473
SV G+CL +E E C + C C + +L ++ G
Sbjct: 249 ---DSVTGECL-EEGFEPPTGMDC----------PTISCDKCVWDLTDALRLAALSIEEG 294
Query: 474 QCLCLSYVTGA 484
+ LS +GA
Sbjct: 295 KSGVLSVSSGA 305
Score = 45.8 bits (107), Expect = 4e-04
Identities = 27/107 (25%), Positives = 43/107 (40%), Gaps = 10/107 (9%)
Query: 1060 ACDRCADGYWNLVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSECQENYYG 1119
AC R A G N P D + ++ T + LG +C ++
Sbjct: 20 ACSRAASGDDNAFP------FDIEGSSAVGRQDPPETSEPRVALGRLPPAAEKCNAGFFH 73
Query: 1120 DPPGRCIPCDCNRAGTQKPICDPDTGMC-RCREGVSGQRCDRCARGH 1165
G C+PCDCN + C +G C C+ +G+ C++C G+
Sbjct: 74 TLSGECVPCDCNGNSNE---CLDGSGYCVHCQRNTTGEHCEKCLDGY 117
Score = 38.1 bits (87), Expect = 0.076
Identities = 28/102 (27%), Positives = 40/102 (39%), Gaps = 20/102 (19%)
Query: 765 GAVACKCHPQGS-----VGSSCSRLGGQCQ-CKPLVVGRCCDRCSTGSYDLGH--HGCHP 816
G+ KC G+ + C + GQC+ C G C+RC+ G Y C
Sbjct: 181 GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV 240
Query: 817 CHCHPQGSKDTVCDQVTGQC-------PCHGEVSGRRCDRCL 851
C+C CD VTG+C P + CD+C+
Sbjct: 241 CNCG-----GGPCDSVTGECLEEGFEPPTGMDCPTISCDKCV 277
>gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens]
Length = 1816
Score = 164 bits (416), Expect = 5e-40
Identities = 91/233 (39%), Positives = 121/233 (51%), Gaps = 33/233 (14%)
Query: 848 DRCLAGYFGFPS--CHPCPCNRFAELCDPETGSCFNCGGFTTGRNCERCIDGYYGNPSSG 905
++C AG+F S C PC CN + C +G C +C TTG +CE+C+DGY G+ G
Sbjct: 65 EKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRG 124
Query: 906 QP--CRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRIS 963
P C+PC CP +N FA SCY+ + V C C + Y G C C+ G+YGNP +
Sbjct: 125 APQFCQPCPCPLPHLAN--FAESCYRK--NGAVRCICNENYAGPNCERCAPGYYGNPLLI 180
Query: 964 GAPCQPCACNNNIDVTDP----ESCSRVTGECLRCLHNTQGANCQLCKPGHYGSA-LNQT 1018
G+ C+ C C+ N +DP E C VTG+C CL NT G C+ C PG+YG A + +
Sbjct: 181 GSTCKKCDCSGN---SDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKN 237
Query: 1019 CRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCADGYWNL 1071
C C+C GGG CD VTG C CD+C W+L
Sbjct: 238 CAVCNC------------GGGP--CDSVTGECLEEGFEPPTGCDKCV---WDL 273
Score = 109 bits (273), Expect = 2e-23
Identities = 66/201 (32%), Positives = 88/201 (43%), Gaps = 28/201 (13%)
Query: 329 CRSCSCNSHSSRCHFDMTTYLASGGLSG-GVCEDCQHNTEGQHCDRCRPLFYRDPLKTIS 387
C C CN +S+ C L G G C CQ NT G+HC++C + D ++
Sbjct: 79 CVPCDCNGNSNEC------------LDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIR--G 124
Query: 388 DPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSAT 447
P C PC C + + A+ +C+C EN G C++C P +YG
Sbjct: 125 APQFCQPCPCPLPHLANFAESCYRKNGAV-----RCICNENYAGPNCERCAPGYYGNPLL 179
Query: 448 DPLGCQPCDC--NPLGSLPFLTCDVDTGQCL-CLSYVTGAHCEECTVGYWGLGNHLHGCS 504
C+ CDC N +L F CD TGQC CL TG CE C GY+G C+
Sbjct: 180 IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCA 239
Query: 505 PCDCDIGGAYSNVCSPKNGQC 525
C+C GG C G+C
Sbjct: 240 VCNC--GG---GPCDSVTGEC 255
Score = 91.3 bits (225), Expect = 8e-18
Identities = 76/243 (31%), Positives = 103/243 (42%), Gaps = 54/243 (22%)
Query: 265 CFCNGHASECRPMQKMRGDVFSPPGMVHGQCV-CQHNTDGPNCERCKDFFQDAPWRPAAD 323
C CNG+++EC + G G CV CQ NT G +CE+C D + R A
Sbjct: 82 CDCNGNSNEC-----LDGS---------GYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQ 127
Query: 324 LQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPL 383
C+ C C +F + Y +G + C C N G +C+RC P +Y +PL
Sbjct: 128 F----CQPCPC-PLPHLANFAESCYRKNGAVR---C-ICNENYAGPNCERCAPGYYGNPL 178
Query: 384 KTISDPYACIPCECDPDGTISGGICVSHSDPAL-----GSVAGQCL-CKENVEGAKCDQC 437
S C C+C +SDP L V GQC C N G KC++C
Sbjct: 179 LIGS---TCKKCDCS-----------GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERC 224
Query: 438 KPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGLG 497
P +YG A C C+C G P CD TG+CL + C++C W L
Sbjct: 225 APGYYG-DARIAKNCAVCNC---GGGP---CDSVTGECLEEGFEPPTGCDKCV---WDLT 274
Query: 498 NHL 500
+ L
Sbjct: 275 DAL 277
Score = 90.5 bits (223), Expect = 1e-17
Identities = 61/192 (31%), Positives = 78/192 (40%), Gaps = 25/192 (13%)
Query: 747 LPGACERLIISMSAKLHDGAVACKCHPQGSVGSSCSRLGGQC-QCKPLVVGRCCDRCSTG 805
LP A E+ L V C C+ + C G C C+ G C++C G
Sbjct: 60 LPPAAEKCNAGFFHTLSGECVPCDCNGNSN---ECLDGSGYCVHCQRNTTGEHCEKCLDG 116
Query: 806 SYDLGHHG----CHPCHC---HPQGSKDTVCDQVTG--QCPCHGEVSGRRCDRCLAGYFG 856
G C PC C H ++ C + G +C C+ +G C+RC GY+G
Sbjct: 117 YIGDSIRGAPQFCQPCPCPLPHLANFAES-CYRKNGAVRCICNENYAGPNCERCAPGYYG 175
Query: 857 FP-----SCHPCPC------NRFAELCDPETGSCFNCGGFTTGRNCERCIDGYYGNPSSG 905
P +C C C N E CD TG C NC TTG CERC GYYG+
Sbjct: 176 NPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIA 235
Query: 906 QPCRPCLCPDDP 917
+ C C C P
Sbjct: 236 KNCAVCNCGGGP 247
Score = 85.1 bits (209), Expect = 5e-16
Identities = 58/187 (31%), Positives = 81/187 (43%), Gaps = 26/187 (13%)
Query: 1006 CKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCA 1065
C G + + L+ C C C+ + EC G G C+ C N TG C++C
Sbjct: 67 CNAGFFHT-LSGECVPCDCNGNS---NECLDGSGYCV--------HCQRNTTGEHCEKCL 114
Query: 1066 DGY-WNLVPG--RGCQSCDCD-PRTSQ-SSHCDQLTG--QCPCKLGYGGKRCSECQENYY 1118
DGY + + G + CQ C C P + + C + G +C C Y G C C YY
Sbjct: 115 DGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174
Query: 1119 GDP---PGRCIPCDCNRAGTQKPI---CDPDTGMCR-CREGVSGQRCDRCARGHSQEFPT 1171
G+P C CDC+ I CD TG CR C +G +C+RCA G+ +
Sbjct: 175 GNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARI 234
Query: 1172 CLQCHLC 1178
C +C
Sbjct: 235 AKNCAVC 241
Score = 75.1 bits (183), Expect = 6e-13
Identities = 55/167 (32%), Positives = 75/167 (44%), Gaps = 30/167 (17%)
Query: 392 CIPCECDPDGTISGGICVSHSDPALGSVAGQCL-CKENVEGAKCDQCKPNHYGLSATD-P 449
C+PC+C+ +S+ L +G C+ C+ N G C++C + G S P
Sbjct: 79 CVPCDCN-----------GNSNECLDG-SGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAP 126
Query: 450 LGCQPCDCNPLGSLPFL--TCDVDTG--QCLCLSYVTGAHCEECTVGYWGLGNHL---HG 502
CQPC C PL L +C G +C+C G +CE C GY+G N L
Sbjct: 127 QFCQPCPC-PLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYG--NPLLIGST 183
Query: 503 CSPCDCDIGGAYSNV----CSPKNGQCE-CRPHVTGRSCSEPAPGYF 544
C CDC G + N+ C GQC C + TG C APGY+
Sbjct: 184 CKKCDCS-GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYY 229
Score = 67.0 bits (162), Expect = 2e-10
Identities = 49/155 (31%), Positives = 65/155 (41%), Gaps = 21/155 (13%)
Query: 403 ISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGS 462
I G V DP S L + KC+ G T C PCDCN +
Sbjct: 36 IEGSSAVGRQDPPETSEPRVALGRLPPAAEKCNA------GFFHTLSGECVPCDCNGNSN 89
Query: 463 LPFLTCDVDTGQCL-CLSYVTGAHCEECTVGYWGLGNHLHG----CSPCDCDIG--GAYS 515
C +G C+ C TG HCE+C GY +G+ + G C PC C + ++
Sbjct: 90 ----ECLDGSGYCVHCQRNTTGEHCEKCLDGY--IGDSIRGAPQFCQPCPCPLPHLANFA 143
Query: 516 NVCSPKNG--QCECRPHVTGRSCSEPAPGYFFAPL 548
C KNG +C C + G +C APGY+ PL
Sbjct: 144 ESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPL 178
Score = 45.8 bits (107), Expect = 4e-04
Identities = 27/107 (25%), Positives = 43/107 (40%), Gaps = 10/107 (9%)
Query: 1060 ACDRCADGYWNLVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSECQENYYG 1119
AC R A G N P D + ++ T + LG +C ++
Sbjct: 20 ACSRAASGDDNAFP------FDIEGSSAVGRQDPPETSEPRVALGRLPPAAEKCNAGFFH 73
Query: 1120 DPPGRCIPCDCNRAGTQKPICDPDTGMC-RCREGVSGQRCDRCARGH 1165
G C+PCDCN + C +G C C+ +G+ C++C G+
Sbjct: 74 TLSGECVPCDCNGNSNE---CLDGSGYCVHCQRNTTGEHCEKCLDGY 117
Score = 42.4 bits (98), Expect = 0.004
Identities = 28/95 (29%), Positives = 39/95 (41%), Gaps = 13/95 (13%)
Query: 765 GAVACKCHPQGS-----VGSSCSRLGGQCQ-CKPLVVGRCCDRCSTGSYDLGH--HGCHP 816
G+ KC G+ + C + GQC+ C G C+RC+ G Y C
Sbjct: 181 GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV 240
Query: 817 CHCHPQGSKDTVCDQVTGQCPCHGEVSGRRCDRCL 851
C+C CD VTG+C G CD+C+
Sbjct: 241 CNCG-----GGPCDSVTGECLEEGFEPPTGCDKCV 270
>gi|157419122 laminin, alpha 4 isoform 2 precursor [Homo sapiens]
Length = 1816
Score = 164 bits (416), Expect = 5e-40
Identities = 91/233 (39%), Positives = 121/233 (51%), Gaps = 33/233 (14%)
Query: 848 DRCLAGYFGFPS--CHPCPCNRFAELCDPETGSCFNCGGFTTGRNCERCIDGYYGNPSSG 905
++C AG+F S C PC CN + C +G C +C TTG +CE+C+DGY G+ G
Sbjct: 65 EKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRG 124
Query: 906 QP--CRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRIS 963
P C+PC CP +N FA SCY+ + V C C + Y G C C+ G+YGNP +
Sbjct: 125 APQFCQPCPCPLPHLAN--FAESCYRK--NGAVRCICNENYAGPNCERCAPGYYGNPLLI 180
Query: 964 GAPCQPCACNNNIDVTDP----ESCSRVTGECLRCLHNTQGANCQLCKPGHYGSA-LNQT 1018
G+ C+ C C+ N +DP E C VTG+C CL NT G C+ C PG+YG A + +
Sbjct: 181 GSTCKKCDCSGN---SDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKN 237
Query: 1019 CRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCADGYWNL 1071
C C+C GGG CD VTG C CD+C W+L
Sbjct: 238 CAVCNC------------GGGP--CDSVTGECLEEGFEPPTGCDKCV---WDL 273
Score = 109 bits (273), Expect = 2e-23
Identities = 66/201 (32%), Positives = 88/201 (43%), Gaps = 28/201 (13%)
Query: 329 CRSCSCNSHSSRCHFDMTTYLASGGLSG-GVCEDCQHNTEGQHCDRCRPLFYRDPLKTIS 387
C C CN +S+ C L G G C CQ NT G+HC++C + D ++
Sbjct: 79 CVPCDCNGNSNEC------------LDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIR--G 124
Query: 388 DPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSAT 447
P C PC C + + A+ +C+C EN G C++C P +YG
Sbjct: 125 APQFCQPCPCPLPHLANFAESCYRKNGAV-----RCICNENYAGPNCERCAPGYYGNPLL 179
Query: 448 DPLGCQPCDC--NPLGSLPFLTCDVDTGQCL-CLSYVTGAHCEECTVGYWGLGNHLHGCS 504
C+ CDC N +L F CD TGQC CL TG CE C GY+G C+
Sbjct: 180 IGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCA 239
Query: 505 PCDCDIGGAYSNVCSPKNGQC 525
C+C GG C G+C
Sbjct: 240 VCNC--GG---GPCDSVTGEC 255
Score = 91.3 bits (225), Expect = 8e-18
Identities = 76/243 (31%), Positives = 103/243 (42%), Gaps = 54/243 (22%)
Query: 265 CFCNGHASECRPMQKMRGDVFSPPGMVHGQCV-CQHNTDGPNCERCKDFFQDAPWRPAAD 323
C CNG+++EC + G G CV CQ NT G +CE+C D + R A
Sbjct: 82 CDCNGNSNEC-----LDGS---------GYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQ 127
Query: 324 LQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPL 383
C+ C C +F + Y +G + C C N G +C+RC P +Y +PL
Sbjct: 128 F----CQPCPC-PLPHLANFAESCYRKNGAVR---C-ICNENYAGPNCERCAPGYYGNPL 178
Query: 384 KTISDPYACIPCECDPDGTISGGICVSHSDPAL-----GSVAGQCL-CKENVEGAKCDQC 437
S C C+C +SDP L V GQC C N G KC++C
Sbjct: 179 LIGS---TCKKCDCS-----------GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERC 224
Query: 438 KPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGLG 497
P +YG A C C+C G P CD TG+CL + C++C W L
Sbjct: 225 APGYYG-DARIAKNCAVCNC---GGGP---CDSVTGECLEEGFEPPTGCDKCV---WDLT 274
Query: 498 NHL 500
+ L
Sbjct: 275 DAL 277
Score = 90.5 bits (223), Expect = 1e-17
Identities = 61/192 (31%), Positives = 78/192 (40%), Gaps = 25/192 (13%)
Query: 747 LPGACERLIISMSAKLHDGAVACKCHPQGSVGSSCSRLGGQC-QCKPLVVGRCCDRCSTG 805
LP A E+ L V C C+ + C G C C+ G C++C G
Sbjct: 60 LPPAAEKCNAGFFHTLSGECVPCDCNGNSN---ECLDGSGYCVHCQRNTTGEHCEKCLDG 116
Query: 806 SYDLGHHG----CHPCHC---HPQGSKDTVCDQVTG--QCPCHGEVSGRRCDRCLAGYFG 856
G C PC C H ++ C + G +C C+ +G C+RC GY+G
Sbjct: 117 YIGDSIRGAPQFCQPCPCPLPHLANFAES-CYRKNGAVRCICNENYAGPNCERCAPGYYG 175
Query: 857 FP-----SCHPCPC------NRFAELCDPETGSCFNCGGFTTGRNCERCIDGYYGNPSSG 905
P +C C C N E CD TG C NC TTG CERC GYYG+
Sbjct: 176 NPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIA 235
Query: 906 QPCRPCLCPDDP 917
+ C C C P
Sbjct: 236 KNCAVCNCGGGP 247
Score = 85.1 bits (209), Expect = 5e-16
Identities = 58/187 (31%), Positives = 81/187 (43%), Gaps = 26/187 (13%)
Query: 1006 CKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCA 1065
C G + + L+ C C C+ + EC G G C+ C N TG C++C
Sbjct: 67 CNAGFFHT-LSGECVPCDCNGNS---NECLDGSGYCV--------HCQRNTTGEHCEKCL 114
Query: 1066 DGY-WNLVPG--RGCQSCDCD-PRTSQ-SSHCDQLTG--QCPCKLGYGGKRCSECQENYY 1118
DGY + + G + CQ C C P + + C + G +C C Y G C C YY
Sbjct: 115 DGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174
Query: 1119 GDP---PGRCIPCDCNRAGTQKPI---CDPDTGMCR-CREGVSGQRCDRCARGHSQEFPT 1171
G+P C CDC+ I CD TG CR C +G +C+RCA G+ +
Sbjct: 175 GNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARI 234
Query: 1172 CLQCHLC 1178
C +C
Sbjct: 235 AKNCAVC 241
Score = 75.1 bits (183), Expect = 6e-13
Identities = 55/167 (32%), Positives = 75/167 (44%), Gaps = 30/167 (17%)
Query: 392 CIPCECDPDGTISGGICVSHSDPALGSVAGQCL-CKENVEGAKCDQCKPNHYGLSATD-P 449
C+PC+C+ +S+ L +G C+ C+ N G C++C + G S P
Sbjct: 79 CVPCDCN-----------GNSNECLDG-SGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAP 126
Query: 450 LGCQPCDCNPLGSLPFL--TCDVDTG--QCLCLSYVTGAHCEECTVGYWGLGNHL---HG 502
CQPC C PL L +C G +C+C G +CE C GY+G N L
Sbjct: 127 QFCQPCPC-PLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYG--NPLLIGST 183
Query: 503 CSPCDCDIGGAYSNV----CSPKNGQCE-CRPHVTGRSCSEPAPGYF 544
C CDC G + N+ C GQC C + TG C APGY+
Sbjct: 184 CKKCDCS-GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYY 229
Score = 67.0 bits (162), Expect = 2e-10
Identities = 49/155 (31%), Positives = 65/155 (41%), Gaps = 21/155 (13%)
Query: 403 ISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGS 462
I G V DP S L + KC+ G T C PCDCN +
Sbjct: 36 IEGSSAVGRQDPPETSEPRVALGRLPPAAEKCNA------GFFHTLSGECVPCDCNGNSN 89
Query: 463 LPFLTCDVDTGQCL-CLSYVTGAHCEECTVGYWGLGNHLHG----CSPCDCDIG--GAYS 515
C +G C+ C TG HCE+C GY +G+ + G C PC C + ++
Sbjct: 90 ----ECLDGSGYCVHCQRNTTGEHCEKCLDGY--IGDSIRGAPQFCQPCPCPLPHLANFA 143
Query: 516 NVCSPKNG--QCECRPHVTGRSCSEPAPGYFFAPL 548
C KNG +C C + G +C APGY+ PL
Sbjct: 144 ESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPL 178
Score = 45.8 bits (107), Expect = 4e-04
Identities = 27/107 (25%), Positives = 43/107 (40%), Gaps = 10/107 (9%)
Query: 1060 ACDRCADGYWNLVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSECQENYYG 1119
AC R A G N P D + ++ T + LG +C ++
Sbjct: 20 ACSRAASGDDNAFP------FDIEGSSAVGRQDPPETSEPRVALGRLPPAAEKCNAGFFH 73
Query: 1120 DPPGRCIPCDCNRAGTQKPICDPDTGMC-RCREGVSGQRCDRCARGH 1165
G C+PCDCN + C +G C C+ +G+ C++C G+
Sbjct: 74 TLSGECVPCDCNGNSNE---CLDGSGYCVHCQRNTTGEHCEKCLDGY 117
Score = 42.4 bits (98), Expect = 0.004
Identities = 28/95 (29%), Positives = 39/95 (41%), Gaps = 13/95 (13%)
Query: 765 GAVACKCHPQGS-----VGSSCSRLGGQCQ-CKPLVVGRCCDRCSTGSYDLGH--HGCHP 816
G+ KC G+ + C + GQC+ C G C+RC+ G Y C
Sbjct: 181 GSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAV 240
Query: 817 CHCHPQGSKDTVCDQVTGQCPCHGEVSGRRCDRCL 851
C+C CD VTG+C G CD+C+
Sbjct: 241 CNCG-----GGPCDSVTGECLEEGFEPPTGCDKCV 270
>gi|122937343 platelet endothelial aggregation receptor 1 [Homo
sapiens]
Length = 1037
Score = 164 bits (415), Expect = 7e-40
Identities = 135/419 (32%), Positives = 168/419 (40%), Gaps = 84/419 (20%)
Query: 769 CKCHPQGSVGSSCSRLGGQCQCKPLVVG-RCCDRCSTGSYDLGHHGCHPCHCHPQGSKDT 827
C+CH G C R GQC+C P G RC + C G + G C C P D
Sbjct: 276 CRCHN----GGLCDRFTGQCRCAPGYTGDRCREECPVGRF--GQDCAETCDCAP----DA 325
Query: 828 VCDQVTGQCPCHGEVSGRRC-DR-CLAGYFGFPSCHPCPCNRFAEL-CDPETGSCFNCGG 884
C G C C +G RC DR C G++G PC C+R L C P G C G
Sbjct: 326 RCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGECSCLPG 385
Query: 885 FTTGRNC-ERCIDGYYGNPSSGQPCRP-CLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQ 942
+ G +C E C + G C+ CLC H S +C C
Sbjct: 386 WA-GLHCNESC-----PQDTHGPGCQEHCLC----------LHGGVCQATSG--LCQCAP 427
Query: 943 GYTGTQCGECSTGFYGNPRISGAPCQP-CACNNNIDVTDPESCSRVTGECLRCLHNTQGA 1001
GYTG C P G C C+C N I +CS + GEC+ C Q
Sbjct: 428 GYTGPHCASLCP-----PDTYGVNCSARCSCENAI------ACSPIDGECV-CKEGWQRG 475
Query: 1002 NCQL-CKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLA 1060
NC + C PG +G + N +C+ C+ A +C P TGAC C P G
Sbjct: 476 NCSVPCPPGTWGFSCNASCQ-CAHEA---------------VCSPQTGACTCTPGWHGAH 519
Query: 1061 CDR-CADGYWNLVPGRGCQS-CDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCS-ECQENY 1117
C C G + G GC S CDCD S CD + G+C C+ G+ G RC C E
Sbjct: 520 CQLPCPKGQF----GEGCASRCDCD----HSDGCDPVHGRCQCQAGWMGARCHLSCPEGL 571
Query: 1118 YGDPPGRCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDR-CARGHSQEFPTCLQC 1175
+G C C GT C P+ G C C G G C R C G + C+ C
Sbjct: 572 WGVNCSN--TCTCKNGGT----CLPENGNCVCAPGFRGPSCQRSCQPGRYGK--RCVPC 622
Score = 127 bits (319), Expect = 1e-28
Identities = 130/467 (27%), Positives = 164/467 (35%), Gaps = 139/467 (29%)
Query: 787 QCQCKPLVVGR-CCDRCSTGSYDLGHHGCHPCHCHPQGSKDTVCDQVTGQCPCHGEVSGR 845
QCQC P G C C+ G + G PC C S CD +G C C +
Sbjct: 119 QCQCVPGWRGDDCSSECAPGMW--GPQCDKPCSCGNNSS----CDPKSGVCSCPSGLQPP 172
Query: 846 RC-DRCLAGYFGFPSCH-PCPCNRFAELCDPETGSCFNCGGFTTGRNCE-RCIDGYYGNP 902
C C GY+G P+C C C+ CDP+TG+CF C TG +C+ C G G
Sbjct: 173 NCLQPCTPGYYG-PACQFRCQCH--GAPCDPQTGACF-CPAERTGPSCDVSCSQGTSG-- 226
Query: 903 SSGQPCRPCLCPDDPSSNQYFAHSCYQN--LWSSDVICNCLQGYTGTQCG-ECSTGFYGN 959
CP HSC + C+C G+ GT C C GF+G
Sbjct: 227 --------FFCPS--------THSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHG- 269
Query: 960 PRISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANC-QLCKPGHYGSALNQT 1018
P S Q C C+N C R TG+C RC G C + C G +G +T
Sbjct: 270 PNCS----QECRCHNG------GLCDRFTGQC-RCAPGYTGDRCREECPVGRFGQDCAET 318
Query: 1019 CRRCSCHASGVSPMECPPGGGACLCD---------------------------------- 1044
C C+ A C P GACLC+
Sbjct: 319 CD-CAPDA------RCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSL 371
Query: 1045 ---PVTGACPCLPNVTGLACDRCADGYWNLVPGRGCQS-CDCDPRTSQSSHCDQLTGQCP 1100
P+ G C CLP GL C+ + G GCQ C C C +G C
Sbjct: 372 SCHPMNGECSCLPGWAGLHCNESCPQDTH---GPGCQEHCLC----LHGGVCQATSGLCQ 424
Query: 1101 CKLGYGGKRCSE-CQENYYG-DPPGRC---------------------------IPC--- 1128
C GY G C+ C + YG + RC +PC
Sbjct: 425 CAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPCPPG 484
Query: 1129 ----DCNRAG--TQKPICDPDTGMCRCREGVSGQRCD-RCARGHSQE 1168
CN + + +C P TG C C G G C C +G E
Sbjct: 485 TWGFSCNASCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGE 531
Score = 77.8 bits (190), Expect = 9e-14
Identities = 76/291 (26%), Positives = 100/291 (34%), Gaps = 59/291 (20%)
Query: 265 CFCNGHASECRPMQKMRGDVFSPPGMVHGQCV--CQHNTDGPNCERCKDFFQDAPWRPAA 322
C C +A C P+ G+ G G C C T G +C +A P
Sbjct: 451 CSCE-NAIACSPID---GECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAVCSP-- 504
Query: 323 DLQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDP 382
Q AC +C+ H + C G E C + H D C P+ R
Sbjct: 505 --QTGAC-TCTPGWHGAHCQLPCP--------KGQFGEGCASRCDCDHSDGCDPVHGRCQ 553
Query: 383 LKT--------ISDPYACIPCECDPDGTI-SGGICVSHSDPALGSVAGQCLCKENVEGAK 433
+ +S P C T +GG C+ + G C+C G
Sbjct: 554 CQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPEN--------GNCVCAPGFRGPS 605
Query: 434 CDQ-CKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEE-CTV 491
C + C+P YG C PC C C G C CL+ TG C + C
Sbjct: 606 CQRSCQPGRYGKR------CVPCKC-----ANHSFCHPSNGTCYCLAGWTGPDCSQPCPP 654
Query: 492 GYWGLGNHLHGCSP-CDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPAP 541
G+WG C+ C C GG C P++G C C TG C E P
Sbjct: 655 GHWG-----ENCAQTCQCHHGGT----CHPQDGSCICPLGWTGHHCLEGCP 696
Score = 75.1 bits (183), Expect = 6e-13
Identities = 83/323 (25%), Positives = 109/323 (33%), Gaps = 62/323 (19%)
Query: 257 YEMIVRGSCFCNG-HASECRPMQKMRGDVFSPPGMVHGQC--VCQHNTDGPNC-ERC--- 309
Y + + C C+ H+ C PM G+ PG C C +T GP C E C
Sbjct: 355 YGLSCQAPCTCDREHSLSCHPMN---GECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCL 411
Query: 310 --------KDFFQDAPWR---------PAADLQDNACRSCSCNSHSSRCHFDMTTYLASG 352
Q AP P N CSC + + D G
Sbjct: 412 HGGVCQATSGLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEG 471
Query: 353 GLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIP------CECD-PDGTISG 405
G C T G C+ + + C P C+ P G
Sbjct: 472 WQRGNCSVPCPPGTWGFSCNASCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGE 531
Query: 406 GICVS-----HSDPALGSVAGQCLCKENVEGAKCD-QCKPNHYGLSATDPLGCQPCDCNP 459
G C S HSD V G+C C+ GA+C C +G++ ++ C C
Sbjct: 532 G-CASRCDCDHSD-GCDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNT-----CTCKN 584
Query: 460 LGSLPFLTCDVDTGQCLCLSYVTGAHCEE-CTVGYWGLGNHLHGCSPCDCDIGGAYSNVC 518
G TC + G C+C G C+ C G +G C PC C A + C
Sbjct: 585 GG-----TCLPENGNCVCAPGFRGPSCQRSCQPGRYG-----KRCVPCKC----ANHSFC 630
Query: 519 SPKNGQCECRPHVTGRSCSEPAP 541
P NG C C TG CS+P P
Sbjct: 631 HPSNGTCYCLAGWTGPDCSQPCP 653
Score = 74.3 bits (181), Expect = 1e-12
Identities = 83/295 (28%), Positives = 100/295 (33%), Gaps = 75/295 (25%)
Query: 264 SCFCNGHASECRPMQKMRGDVFSPPGM--VHGQCVCQHNTDGPNC-ERCKDFFQDAPWRP 320
SC C H + C P G PG H Q C G C RC D
Sbjct: 493 SCQC-AHEAVCSPQT---GACTCTPGWHGAHCQLPCPKGQFGEGCASRC-----DCDHSD 543
Query: 321 AADLQDNACRSCSCNSHSSRCHFDMTTYLASGGLS-------GGVCED------CQHNTE 367
D C+ C +RCH L S GG C C
Sbjct: 544 GCDPVHGRCQ-CQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPENGNCVCAPGFR 602
Query: 368 GQHCDR-CRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSHS--DPALGSVAGQCL 424
G C R C+P Y C+PC+C +HS P+ G+ C
Sbjct: 603 GPSCQRSCQPGRYGK---------RCVPCKC-----------ANHSFCHPSNGT----CY 638
Query: 425 CKENVEGAKCDQ-CKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTG 483
C G C Q C P H+G + Q C C+ G TC G C+C TG
Sbjct: 639 CLAGWTGPDCSQPCPPGHWGENCA-----QTCQCHHGG-----TCHPQDGSCICPLGWTG 688
Query: 484 AHC-EECTVGYWGLGNHLHGCS-PCDCDIGGAYSNVCSPKNGQCECRPHVTGRSC 536
HC E C +G +G CS PC C G C P+ G C C P +G C
Sbjct: 689 HHCLEGCPLGTFGAN-----CSQPCQCGPG----EKCHPETGACVCPPGHSGAPC 734
Score = 72.0 bits (175), Expect = 5e-12
Identities = 64/257 (24%), Positives = 90/257 (35%), Gaps = 69/257 (26%)
Query: 292 HGQCVCQHNTDGPNC--ERCKDFFQDAPWRPAADLQDNACRS-CSCN-SHSSRCHFDMTT 347
+G C+C+H G C C D F +C++ C+C+ HS CH
Sbjct: 331 NGACLCEHGFTGDRCTDRLCPDGFYGL-----------SCQAPCTCDREHSLSCHPMNGE 379
Query: 348 YLASGGLSGGVC-EDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGG 406
G +G C E C +T G C C C + GG
Sbjct: 380 CSCLPGWAGLHCNESCPQDTHGPGCQE--------------------HCLC-----LHGG 414
Query: 407 ICVSHSDPALGSVAGQCLCKENVEGAKCDQ-CKPNHYGLSATDPLGCQPCDCNPLGSLPF 465
+C + S G C C G C C P+ YG++ + C+
Sbjct: 415 VCQATS--------GLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENA---------- 456
Query: 466 LTCDVDTGQCLCLSYVTGAHCE-ECTVGYWGLGNHLHGCSPCDCDIGGAYSNVCSPKNGQ 524
+ C G+C+C +C C G WG + + C C A+ VCSP+ G
Sbjct: 457 IACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCN----ASCQC----AHEAVCSPQTGA 508
Query: 525 CECRPHVTGRSCSEPAP 541
C C P G C P P
Sbjct: 509 CTCTPGWHGAHCQLPCP 525
Score = 64.7 bits (156), Expect = 8e-10
Identities = 80/268 (29%), Positives = 96/268 (35%), Gaps = 50/268 (18%)
Query: 291 VHGQCVCQHNTD---GPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTT 347
VHG+CV + G + C W P D + CSC ++SS C
Sbjct: 110 VHGRCVAPNQCQCVPGWRGDDCSSECAPGMWGPQCD------KPCSCGNNSS-CDPKSGV 162
Query: 348 YLASGGLSGGVC-EDCQHNTEGQHCD-RCRPLFYRDPLKTISDPYACIPCE-----CD-- 398
GL C + C G C RC+ + P + C P E CD
Sbjct: 163 CSCPSGLQPPNCLQPCTPGYYGPACQFRCQ--CHGAPCDPQTGACFC-PAERTGPSCDVS 219
Query: 399 -PDGTISGGICVSHSDPALGSV----AGQCLCKENVEGAKCD-QCKPNHYGLSATDPLGC 452
GT SG C S G V G C C G C C +G P
Sbjct: 220 CSQGT-SGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHG-----PNCS 273
Query: 453 QPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHC-EECTVGYWGLGNHLHGCSP-CDCDI 510
Q C C+ G CD TGQC C TG C EEC VG +G C+ CDC
Sbjct: 274 QECRCHNGG-----LCDRFTGQCRCAPGYTGDRCREECPVGRFG-----QDCAETCDC-- 321
Query: 511 GGAYSNVCSPKNGQCECRPHVTGRSCSE 538
A C P NG C C TG C++
Sbjct: 322 --APDARCFPANGACLCEHGFTGDRCTD 347
Score = 53.1 bits (126), Expect = 2e-06
Identities = 45/160 (28%), Positives = 58/160 (36%), Gaps = 42/160 (26%)
Query: 394 PCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQ-CKPNHYGLSATDPLGC 452
PC C + S DP +G C C ++ C Q C P +YG + C
Sbjct: 147 PCSCGNN---------SSCDPK----SGVCSCPSGLQPPNCLQPCTPGYYGPA------C 187
Query: 453 Q-PCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCE----ECTVGYWGLGNHLHGCSPCD 507
Q C C+ CD TG C C + TG C+ + T G++ H
Sbjct: 188 QFRCQCHGA------PCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPSTH-------S 234
Query: 508 CDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPAPGYFFAP 547
C GG + G C C P G CS P P F P
Sbjct: 235 CQNGGVFQT----PQGSCSCPPGWMGTICSLPCPEGFHGP 270
Score = 42.0 bits (97), Expect = 0.005
Identities = 26/78 (33%), Positives = 34/78 (43%), Gaps = 12/78 (15%)
Query: 470 VDTGQCLCLSYVTGAHCE-ECTVGYWGLGNHLHGCS-PCDCDIGGAYSNVCSPKNGQCEC 527
V QC C+ G C EC G WG C PC C ++ C PK+G C C
Sbjct: 115 VAPNQCQCVPGWRGDDCSSECAPGMWG-----PQCDKPCSC----GNNSSCDPKSGVCSC 165
Query: 528 RPHVTGRSCSEP-APGYF 544
+ +C +P PGY+
Sbjct: 166 PSGLQPPNCLQPCTPGYY 183
>gi|14192943 multiple EGF-like-domains 10 [Homo sapiens]
Length = 1140
Score = 163 bits (413), Expect = 1e-39
Identities = 130/398 (32%), Positives = 163/398 (40%), Gaps = 76/398 (19%)
Query: 778 GSSCSRLGGQCQCKPLVVGRCCDR-CSTGSYDLGHHGCHPCHCHPQGSKDTVCDQVTGQC 836
G C + G+C C +G C + C G + G + C CH G+ CD TGQC
Sbjct: 243 GGVCHHVTGECSCPSGWMGTVCGQPCPEGRF--GKNCSQECQCHNGGT----CDAATGQC 296
Query: 837 PCHGEVSGRRC-DRCLAGYFGFPSCHPCPCNRFAELCDPETGSCFNCGGFTTGRNCER-- 893
C +G RC D C G +G C C + C +G+C GF G CE
Sbjct: 297 HCSPGYTGERCQDECPVGTYGVLCAETCQCVNGGK-CYHVSGACLCEAGFA-GERCEARL 354
Query: 894 CIDGYYGNPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGE-C 952
C +G YG + C C + + HSC+ C C G++G C E C
Sbjct: 355 CPEGLYGIKCD----KRCPCHLENT------HSCHPMSGE----CACKPGWSGLYCNETC 400
Query: 953 STGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQL-CKPGHY 1011
S GFYG A Q C+C N D C VTG+C C +G +C C G Y
Sbjct: 401 SPGFYGE-----ACQQICSCQNGAD------CDSVTGKCT-CAPGFKGIDCSTPCPLGTY 448
Query: 1012 GSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACD-RCADGYWN 1070
G + RC C V C PV G+C C G+ C RC G W
Sbjct: 449 GINCSS---RCGCKNDAV-------------CSPVDGSCTCKAGWHGVDCSIRCPSGTW- 491
Query: 1071 LVPGRGCQ-SCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCS-ECQENYYGDPPGRCIP- 1127
G GC +C C C+ L G C C G+ G++C CQ+ YG C
Sbjct: 492 ---GFGCNLTCQC----LNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYG---LNCAER 541
Query: 1128 CDCNRAGTQKPICDPDTGMCRCREGVSGQRCDR-CARG 1164
CDC+ A C P TG CRC G SG CD CA G
Sbjct: 542 CDCSHADG----CHPTTGHCRCLPGWSGVHCDSVCAEG 575
Score = 161 bits (407), Expect = 6e-39
Identities = 128/393 (32%), Positives = 166/393 (42%), Gaps = 76/393 (19%)
Query: 778 GSSCSRLGGQCQCKPLVVGRCCDR-CSTGSYDLGHHGCHPCHC-HPQGSKDTVCDQVTGQ 835
G +C+ L G C C P G C+ C G+Y L + C C H G C TG
Sbjct: 504 GGACNTLDGTCTCAPGWRGEKCELPCQDGTYGL--NCAERCDCSHADG-----CHPTTGH 556
Query: 836 CPCHGEVSGRRCDR-CLAGYFGFPSCH-PCPCNRFAELCDPETGSCFNCGGFTTGRNCER 893
C C SG CD C G +G P+C PC C A C P+ G C GF G C+R
Sbjct: 557 CRCLPGWSGVHCDSVCAEGRWG-PNCSLPCYCKNGAS-CSPDDGICECAPGFR-GTTCQR 613
Query: 894 -CIDGYYGNPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGE- 951
C G+YG+ S Q C C+ P C+ +C+CL G+TG C E
Sbjct: 614 ICSPGFYGHRCS-QTCPQCVHSSGP---------CHHITG----LCDCLPGFTGALCNEV 659
Query: 952 CSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANC-QLCKPGH 1010
C +G +G +G C C NN +C+ + C +C G++C Q C P H
Sbjct: 660 CPSGRFGK-NCAGI----CTCTNN------GTCNPIDRSC-QCYPGWIGSDCSQPCPPAH 707
Query: 1011 YGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLAC-DRCADGYW 1069
+G TC +CH C G C C P TGL C RC G++
Sbjct: 708 WGPNCIHTC---NCH-------------NGAFCSAYDGECKCTPGWTGLYCTQRCPLGFY 751
Query: 1070 NLVPGRGCQS-CDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSE-CQENYYGDPPGRCIP 1127
G+ C C C + CD ++GQC C+ G+ G+ C + C YG G
Sbjct: 752 ----GKDCALICQCQ----NGADCDHISGQCTCRTGFMGRHCEQKCPSGTYG--YGCRQI 801
Query: 1128 CDCNRAGTQKPICDPDTGMCRCREGVSGQRCDR 1160
CDC T CD TG C C G G RCD+
Sbjct: 802 CDCLNNST----CDHITGTCYCSPGWKGARCDQ 830
Score = 157 bits (396), Expect = 1e-37
Identities = 148/525 (28%), Positives = 187/525 (35%), Gaps = 150/525 (28%)
Query: 769 CKCHPQGSVGSSCSRLGGQCQCKPLVVG-RCCDRCSTGSYDLGHHGCHPCHCHPQGSKDT 827
C Q G+ C+ + G C C G RC DRC G+Y + CH Q
Sbjct: 148 CTSRCQCKNGALCNPITGACHCAAGFRGWRCEDRCEQGTYG------NDCHQRCQCQNGA 201
Query: 828 VCDQVTGQCPC-----------------HGEVSGRRCD--------------RCLAGYFG 856
CD VTG+C C HG +RC C +G+ G
Sbjct: 202 TCDHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSGWMG 261
Query: 857 FPSCHPCPCNRFAE------------LCDPETGSCFNCGGFTTGRNCERCIDGYYG---- 900
PCP RF + CD TG C G+T R + C G YG
Sbjct: 262 TVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSPGYTGERCQDECPVGTYGVLCA 321
Query: 901 ---NPSSGQPC----RPCLCPDDPSSNQYFAHSCYQNLWS-------------------S 934
+G C CLC + + A C + L+
Sbjct: 322 ETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSCHPM 381
Query: 935 DVICNCLQGYTGTQCGE-CSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLR 993
C C G++G C E CS GFYG A Q C+C N D C VTG+C
Sbjct: 382 SGECACKPGWSGLYCNETCSPGFYGE-----ACQQICSCQNGAD------CDSVTGKC-T 429
Query: 994 CLHNTQGANCQL-CKPGHYGSALNQTC------------RRCSCHAS--GVS-PMECPPG 1037
C +G +C C G YG + C C+C A GV + CP G
Sbjct: 430 CAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSG 489
Query: 1038 --------------GGACLCDPVTGACPCLPNVTGLACD-RCADGYWNLVPGRGCQSCDC 1082
GGA C+ + G C C P G C+ C DG + L + CDC
Sbjct: 490 TWGFGCNLTCQCLNGGA--CNTLDGTCTCAPGWRGEKCELPCQDGTYGL---NCAERCDC 544
Query: 1083 DPRTSQSSHCDQLTGQCPCKLGYGGKRC-SECQENYYGDPPGRCIPCDCNRAGTQKPICD 1141
S + C TG C C G+ G C S C E +G P +PC C + C
Sbjct: 545 ----SHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWG--PNCSLPCYCKNGAS----CS 594
Query: 1142 PDTGMCRCREGVSGQRCDR-CARGH-----SQEFPTCLQ----CH 1176
PD G+C C G G C R C+ G SQ P C+ CH
Sbjct: 595 PDDGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCH 639
Score = 112 bits (280), Expect = 3e-24
Identities = 101/331 (30%), Positives = 126/331 (38%), Gaps = 71/331 (21%)
Query: 839 HGEVSG-RRCDRCLAGYF-GFPSCHPCPCNR--FAELCDPETGSCFNCGGFTTGRNCERC 894
HGE + RR +C G++ C P ++ P T C G G NC
Sbjct: 82 HGEKTMYRRKSQCCPGFYESGEMCVPHCADKCVHGRCIAPNTCQCEPGWG---GTNCSSA 138
Query: 895 IDGYYGNPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGE-CS 953
DG + P C+ C + N C+C G+ G +C + C
Sbjct: 139 CDGDHWGPHCTSRCQ---CKNGALCNPITG------------ACHCAAGFRGWRCEDRCE 183
Query: 954 TGFYGNPRISGAPC-QPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQ-LCKPGHY 1011
G YGN C Q C C N +C VTGEC RC GA C+ LC PG +
Sbjct: 184 QGTYGND------CHQRCQCQNGA------TCDHVTGEC-RCPPGYTGAFCEDLCPPGKH 230
Query: 1012 GSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDR-CADGYWN 1070
G Q RC C GV C VTG C C G C + C +G +
Sbjct: 231 GPQCEQ---RCPCQNGGV-------------CHHVTGECSCPSGWMGTVCGQPCPEGRF- 273
Query: 1071 LVPGRGC-QSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRC-SECQENYYGDPPGRCIPC 1128
G+ C Q C C CD TGQC C GY G+RC EC YG C
Sbjct: 274 ---GKNCSQECQCH----NGGTCDAATGQCHCSPGYTGERCQDECPVGTYGVLCAE--TC 324
Query: 1129 DCNRAGTQKPICDPDTGMCRCREGVSGQRCD 1159
C G C +G C C G +G+RC+
Sbjct: 325 QCVNGGK----CYHVSGACLCEAGFAGERCE 351
Score = 82.4 bits (202), Expect = 4e-15
Identities = 84/334 (25%), Positives = 117/334 (35%), Gaps = 81/334 (24%)
Query: 272 SECRPMQKMRGDVFSP---PGMVHGQCV------CQHNTDGPNCERCKDFFQDAPWRPAA 322
S+C P G++ P VHG+C+ C+ G NC D W P
Sbjct: 92 SQCCPGFYESGEMCVPHCADKCVHGRCIAPNTCQCEPGWGGTNCSSACD---GDHWGPHC 148
Query: 323 DLQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCED-CQHNTEGQHCDRCRPLFYRD 381
+ CN + CH + G G CED C+ T G C +
Sbjct: 149 TSRCQCKNGALCNPITGACH-------CAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGA 201
Query: 382 PLKTISDPYACIP------CE--CDPD--GTISGGICVSHSDPALGSVAGQCLCKENVEG 431
++ C P CE C P G C + V G+C C G
Sbjct: 202 TCDHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSGWMG 261
Query: 432 AKCDQ-CKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCE-EC 489
C Q C +G + + Q C C+ G TCD TGQC C TG C+ EC
Sbjct: 262 TVCGQPCPEGRFGKNCS-----QECQCHNGG-----TCDAATGQCHCSPGYTGERCQDEC 311
Query: 490 TVGYWGL-----------GNHLHGCSPCDCDIG-------------GAY----------- 514
VG +G+ G H C C+ G G Y
Sbjct: 312 PVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCH 371
Query: 515 ---SNVCSPKNGQCECRPHVTGRSCSEP-APGYF 544
++ C P +G+C C+P +G C+E +PG++
Sbjct: 372 LENTHSCHPMSGECACKPGWSGLYCNETCSPGFY 405
Score = 70.9 bits (172), Expect = 1e-11
Identities = 70/292 (23%), Positives = 97/292 (33%), Gaps = 58/292 (19%)
Query: 265 CFCNGHASECRPMQKMRGDVFSPPGMVHGQCVCQHNTDGPNCERCKDFFQDAPWRPAADL 324
C C+ HA C P G C C G +C+ + W P L
Sbjct: 542 CDCS-HADGCHPTT--------------GHCRCLPGWSGVHCD---SVCAEGRWGPNCSL 583
Query: 325 QDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCED-CQHNTEGQHCDRCRP--LFYRD 381
SC+ C + G G C+ C G C + P +
Sbjct: 584 PCYCKNGASCSPDDGICE-------CAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSG 636
Query: 382 PLKTISDPYACIP----------CECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEG 431
P I+ C+P C G GIC ++ + C C G
Sbjct: 637 PCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIG 696
Query: 432 AKCDQ-CKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHC-EEC 489
+ C Q C P H+G P C+C+ G+ C G+C C TG +C + C
Sbjct: 697 SDCSQPCPPAHWG-----PNCIHTCNCHN-GAF----CSAYDGECKCTPGWTGLYCTQRC 746
Query: 490 TVGYWGLGNHLHGCSPCDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPAP 541
+G++G L C C G C +GQC CR GR C + P
Sbjct: 747 PLGFYGKDCALI----CQCQNGAD----CDHISGQCTCRTGFMGRHCEQKCP 790
Score = 70.5 bits (171), Expect = 1e-11
Identities = 77/310 (24%), Positives = 97/310 (31%), Gaps = 80/310 (25%)
Query: 291 VHGQCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSC---NSHSSRCHFDMTT 347
V G C+C+ G CE A P + C C N+HS CH
Sbjct: 335 VSGACLCEAGFAGERCE--------ARLCPEGLYGIKCDKRCPCHLENTHS--CHPMSGE 384
Query: 348 YLASGGLSGGVC-EDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIP----------CE 396
G SG C E C G+ C + +++ C P C
Sbjct: 385 CACKPGWSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTGKCTCAPGFKGIDCSTPCP 444
Query: 397 CDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCD--------------------- 435
G C +D V G C CK G C
Sbjct: 445 LGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNG 504
Query: 436 ----------QCKPNHYGLSATDP-------LGC-QPCDCNPLGSLPFLTCDVDTGQCLC 477
C P G P L C + CDC+ C TG C C
Sbjct: 505 GACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADG-----CHPTTGHCRC 559
Query: 478 LSYVTGAHCEE-CTVGYWGLGNHLHGCS-PCDCDIGGAYSNVCSPKNGQCECRPHVTGRS 535
L +G HC+ C G WG CS PC C G + CSP +G CEC P G +
Sbjct: 560 LPGWSGVHCDSVCAEGRWG-----PNCSLPCYCKNGAS----CSPDDGICECAPGFRGTT 610
Query: 536 CSE-PAPGYF 544
C +PG++
Sbjct: 611 CQRICSPGFY 620
Score = 68.9 bits (167), Expect = 4e-11
Identities = 56/195 (28%), Positives = 80/195 (41%), Gaps = 33/195 (16%)
Query: 769 CKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDR-CSTGSYDLGHHGCHPCHCHPQGSKDT 827
C C G+ C+ + CQC P +G C + C + G + H C+CH
Sbjct: 673 CTCTNNGT----CNPIDRSCQCYPGWIGSDCSQPCPPAHW--GPNCIHTCNCH----NGA 722
Query: 828 VCDQVTGQCPCHGEVSGRRC-DRCLAGYFGFPSCHPCPCNRFAELCDPETGSCFNCGGFT 886
C G+C C +G C RC G++G C C A+ CD +G C GF
Sbjct: 723 FCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGAD-CDHISGQCTCRTGFM 781
Query: 887 TGRNCE-RCIDGYYGNPSSGQPCRP-CLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGY 944
GR+CE +C G YG CR C C ++ S+ + +CY C G+
Sbjct: 782 -GRHCEQKCPSGTYG-----YGCRQICDCLNN-STCDHITGTCY-----------CSPGW 823
Query: 945 TGTQCGECSTGFYGN 959
G +C + GN
Sbjct: 824 KGARCDQAGVIIVGN 838
Score = 67.8 bits (164), Expect = 9e-11
Identities = 75/298 (25%), Positives = 98/298 (32%), Gaps = 45/298 (15%)
Query: 265 CFCNGHASECRPMQKMRGDVFSPPGMVHGQCVCQHNTDGPNCE-RCKDFFQDAPWRPAAD 323
C + C + D P V G C C+ G +C RC W +
Sbjct: 443 CPLGTYGINCSSRCGCKNDAVCSP--VDGSCTCKAGWHGVDCSIRCPS----GTWGFGCN 496
Query: 324 LQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCE-DCQHNTEGQHCDRCRPLFYRDP 382
L +CN+ C + G G CE CQ T G +C + D
Sbjct: 497 LTCQCLNGGACNTLDGTC-------TCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADG 549
Query: 383 LKTISDPYACIP----CECDPD------GTISGGICVSHSDPALGSVAGQCLCKENVEGA 432
+ C+P CD G C + + G C C G
Sbjct: 550 CHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGFRGT 609
Query: 433 KCDQ-CKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEE-CT 490
C + C P YG + Q C S P C TG C CL TGA C E C
Sbjct: 610 TCQRICSPGFYGHRCS-----QTCPQCVHSSGP---CHHITGLCDCLPGFTGALCNEVCP 661
Query: 491 VGYWGLGNHLHGCSP-CDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPAPGYFFAP 547
G +G C+ C C G C+P + C+C P G CS+P P + P
Sbjct: 662 SGRFG-----KNCAGICTCTNNGT----CNPIDRSCQCYPGWIGSDCSQPCPPAHWGP 710
Score = 65.1 bits (157), Expect = 6e-10
Identities = 70/274 (25%), Positives = 94/274 (34%), Gaps = 55/274 (20%)
Query: 293 GQCVCQHNTDGPNCER-CKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLAS 351
G C C G CE C+D N C C SH+ CH
Sbjct: 512 GTCTCAPGWRGEKCELPCQDGTYGL----------NCAERCDC-SHADGCHPTTGHCRCL 560
Query: 352 GGLSGGVCED-CQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPD--GTISGGIC 408
G SG C+ C G +C P + ++ D C EC P GT IC
Sbjct: 561 PGWSGVHCDSVCAEGRWGPNCSL--PCYCKNGASCSPDDGIC---ECAPGFRGTTCQRIC 615
Query: 409 VS---------------HSDPALGSVAGQCLCKENVEGAKCDQ-CKPNHYGLSATDPLGC 452
HS + G C C GA C++ C +G +
Sbjct: 616 SPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGI--- 672
Query: 453 QPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEE-CTVGYWGLGNHLHGCSPCDCDIG 511
C C G TC+ C C G+ C + C +WG N +H C+C G
Sbjct: 673 --CTCTNNG-----TCNPIDRSCQCYPGWIGSDCSQPCPPAHWG-PNCIH---TCNCHNG 721
Query: 512 GAYSNVCSPKNGQCECRPHVTGRSCSEPAPGYFF 545
CS +G+C+C P TG C++ P F+
Sbjct: 722 A----FCSAYDGECKCTPGWTGLYCTQRCPLGFY 751
Score = 50.1 bits (118), Expect = 2e-05
Identities = 67/261 (25%), Positives = 92/261 (35%), Gaps = 75/261 (28%)
Query: 263 GSCFCNGHASECRPMQKMRGDVFSPPGMVHGQCVCQHNTDGPNCER-CKDFFQDAPWRPA 321
G C C + + C P+ + C C G +C + C A W P
Sbjct: 671 GICTCTNNGT-CNPIDR--------------SCQCYPGWIGSDCSQPCPP----AHWGP- 710
Query: 322 ADLQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPL-FYR 380
N +C+C++ + +D G C+ C G +C + PL FY
Sbjct: 711 -----NCIHTCNCHNGAFCSAYD------------GECK-CTPGWTGLYCTQRCPLGFYG 752
Query: 381 DPLKTISDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPN 440
I C+C +G C ++GQC C+ G C+Q P
Sbjct: 753 KDCALI--------CQCQ-----NGADC--------DHISGQCTCRTGFMGRHCEQKCP- 790
Query: 441 HYGLSATDPLGC-QPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGLGNH 499
S T GC Q CDC L TCD TG C C GA C++ V G N
Sbjct: 791 ----SGTYGYGCRQICDC-----LNNSTCDHITGTCYCSPGWKGARCDQAGVIIVGNLNS 841
Query: 500 LHGCS---PCDCDIGGAYSNV 517
L S P D GA + +
Sbjct: 842 LSRTSTALPADSYQIGAIAGI 862
>gi|24308065 netrin 5 [Homo sapiens]
Length = 489
Score = 163 bits (412), Expect = 2e-39
Identities = 79/193 (40%), Positives = 105/193 (54%), Gaps = 22/193 (11%)
Query: 261 VRGSCFCNGHASECRPMQKMRGDVFSPPGMVHGQCVCQHNTDGPNCERCKDFFQDAPWRP 320
+RG C C+GHA+ C + PP +C C+H+T GP CE C+ +D PWRP
Sbjct: 153 LRGRCQCHGHAARCAARAR-------PP-----RCHCRHHTTGPGCESCRPSHRDWPWRP 200
Query: 321 AADLQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYR 380
A + C CSCN H+ RC F+ + SGG SGGVCE C+H+T G+HC C+P F+R
Sbjct: 201 ATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWR 260
Query: 381 DPLKTISDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPN 440
DP + I AC C+C P G +GG C +GQC CK V G C++C P
Sbjct: 261 DPSQPIFSRRACRACQCHPIGA-TGGTC--------NQTSGQCTCKLGVTGLTCNRCGPG 311
Query: 441 HYGLSATDPLGCQ 453
Y S + + CQ
Sbjct: 312 -YQQSRSPRMPCQ 323
Score = 72.8 bits (177), Expect = 3e-12
Identities = 41/139 (29%), Positives = 57/139 (41%), Gaps = 17/139 (12%)
Query: 422 QCLCKENVEGAKCDQCKPNHYG-----LSATDPLGCQPCDCNPLG-------SLPFLTCD 469
+C C+ + G C+ C+P+H + P C PC CN L L+
Sbjct: 174 RCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGG 233
Query: 470 VDTGQC-LCLSYVTGAHCEECTVGYWGLGNH----LHGCSPCDCDIGGAYSNVCSPKNGQ 524
G C C + G HC C G+W + C C C GA C+ +GQ
Sbjct: 234 RSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQ 293
Query: 525 CECRPHVTGRSCSEPAPGY 543
C C+ VTG +C+ PGY
Sbjct: 294 CTCKLGVTGLTCNRCGPGY 312
Score = 71.6 bits (174), Expect = 6e-12
Identities = 54/204 (26%), Positives = 74/204 (36%), Gaps = 45/204 (22%)
Query: 946 GTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQL 1005
G Q G + G G + G + CA P C C H+T G C+
Sbjct: 143 GGQAGLAAAGLRGRCQCHGHAAR-CAARAR-----PPRC--------HCRHHTTGPGCES 188
Query: 1006 CKPGHYG----------------SALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGA 1049
C+P H + NQ RRC + S + + GG C
Sbjct: 189 CRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFN-SELFRLSGGRSGGVCE------- 240
Query: 1050 CPCLPNVTGLACDRCADGYWN-----LVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKLG 1104
C + G C C G+W + R C++C C P + C+Q +GQC CKLG
Sbjct: 241 -RCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQCTCKLG 299
Query: 1105 YGGKRCSECQENYYGDPPGRCIPC 1128
G C+ C Y R +PC
Sbjct: 300 VTGLTCNRCGPGYQQSRSPR-MPC 322
Score = 65.9 bits (159), Expect = 3e-10
Identities = 46/189 (24%), Positives = 64/189 (33%), Gaps = 32/189 (16%)
Query: 1009 GHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCADGY 1068
G G A RC CH C C C + TG C+ C +
Sbjct: 144 GQAGLAAAGLRGRCQCHGHAAR----------CAARARPPRCHCRHHTTGPGCESCRPSH 193
Query: 1069 --WNLVPG-----RGCQSCDCDPRTSQSSHCDQLT--------GQCP-CKLGYGGKRCSE 1112
W P C C C+ + +L G C C+ G+ C
Sbjct: 194 RDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHY 253
Query: 1113 CQENYYGDPPG------RCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDRCARGHS 1166
CQ ++ DP C C C+ G C+ +G C C+ GV+G C+RC G+
Sbjct: 254 CQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGPGYQ 313
Query: 1167 QEFPTCLQC 1175
Q + C
Sbjct: 314 QSRSPRMPC 322
Score = 65.1 bits (157), Expect = 6e-10
Identities = 47/177 (26%), Positives = 65/177 (36%), Gaps = 35/177 (19%)
Query: 817 CHCHPQGSKDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFP----------SCHPCPCN 866
C CH ++ + +C C +G C+ C + +P C PC CN
Sbjct: 157 CQCHGHAARCAARARPP-RCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCN 215
Query: 867 RFAELCDPET-----------GSCFNCGGFTTGRNCERCIDGYYGNPS----SGQPCRPC 911
+ A C + G C C T GR+C C G++ +PS S + CR C
Sbjct: 216 QHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRAC 275
Query: 912 LCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQ 968
C ++ +C Q C C G TG C C G Y R PCQ
Sbjct: 276 QCHPIGAT----GGTCNQTSGQ----CTCKLGVTGLTCNRCGPG-YQQSRSPRMPCQ 323
Score = 62.4 bits (150), Expect = 4e-09
Identities = 35/98 (35%), Positives = 43/98 (43%), Gaps = 8/98 (8%)
Query: 780 SCSRLGGQCQ-CKPLVVGRCCDRCSTGSYD------LGHHGCHPCHCHPQGSKDTVCDQV 832
S R GG C+ C+ GR C C G + C C CHP G+ C+Q
Sbjct: 231 SGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQT 290
Query: 833 TGQCPCHGEVSGRRCDRCLAGYFGFPSCHPCPCNRFAE 870
+GQC C V+G C+RC GY S PC R E
Sbjct: 291 SGQCTCKLGVTGLTCNRCGPGYQQSRSPR-MPCQRIPE 327
Score = 53.1 bits (126), Expect = 2e-06
Identities = 23/57 (40%), Positives = 31/57 (54%), Gaps = 1/57 (1%)
Query: 768 ACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHGCHPCHCHPQGS 824
AC+CHP G+ G +C++ GQC CK V G C+RC G Y PC P+ +
Sbjct: 274 ACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGPG-YQQSRSPRMPCQRIPEAT 329
Score = 42.0 bits (97), Expect = 0.005
Identities = 27/89 (30%), Positives = 33/89 (37%), Gaps = 15/89 (16%)
Query: 474 QCLCLSYVTGAHCEECTVGY----W--GLGNHLHGCSPCDCDIGGAYSNVCSP------- 520
+C C + TG CE C + W H H C PC C+ S
Sbjct: 174 RCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGG 233
Query: 521 -KNGQCE-CRPHVTGRSCSEPAPGYFFAP 547
G CE CR H GR C PG++ P
Sbjct: 234 RSGGVCERCRHHTAGRHCHYCQPGFWRDP 262
>gi|157419140 laminin, gamma 2 isoform b precursor [Homo sapiens]
Length = 1111
Score = 158 bits (399), Expect = 5e-38
Identities = 83/233 (35%), Positives = 114/233 (48%), Gaps = 26/233 (11%)
Query: 835 QCPCHGEVSGRRCDRCLAGYFG-------FPSCHPCPCNRFAELCDPETGSCFNCGGFTT 887
QC C G+ C C +GY F +C PC C CDP+TG C++ G
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQG-GGACDPDTGDCYS-GDENP 438
Query: 888 GRNCERCIDGYYGNPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICN-CLQGYTG 946
C C G+Y +P + C+PC C + SC + +V+CN C G TG
Sbjct: 439 DIECADCPIGFYNDPHDPRSCKPCPCHN--------GFSCSVMPETEEVVCNNCPPGVTG 490
Query: 947 TQCGECSTGFYGNPRISGAP---CQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANC 1003
+C C+ G++G+P P CQPC CNNN+D + +C R+TG CL+C+HNT G C
Sbjct: 491 ARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYC 550
Query: 1004 QLCKPGHYGSAL----NQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPC 1052
CK G++G L CR C+C+ G P+ C G C+C P G C
Sbjct: 551 DQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGC-RSDGTCVCKPGFGGPNC 602
Score = 136 bits (342), Expect = 2e-31
Identities = 178/807 (22%), Positives = 316/807 (39%), Gaps = 159/807 (19%)
Query: 938 CNCLQGYTGTQCGECSTGFYGNPRISG--APCQPCACNNNIDVTDPESCSRVTGECLRCL 995
C C GY G C +C++G+ + G C PC C +C TG+C
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGG------GACDPDTGDCYSGD 435
Query: 996 HNTQGANCQLCKPGHYGSALN-QTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCL- 1053
N C C G Y + ++C+ C CH G +C P T C
Sbjct: 436 ENPD-IECADCPIGFYNDPHDPRSCKPCPCH-----------NGFSCSVMPETEEVVCNN 483
Query: 1054 --PNVTGLACDRCADGYW-----NLVPGRGCQSCDCDPRT--SQSSHCDQLTGQC-PCKL 1103
P VTG C+ CADGY+ P R CQ C C+ S S +CD+LTG+C C
Sbjct: 484 CPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIH 543
Query: 1104 GYGGKRCSECQENYYGD-----PPGRCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRC 1158
G C +C+ Y+GD P +C C+CN G++ C D G C C+ G G C
Sbjct: 544 NTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGCRSD-GTCVCKPGFGGPNC 602
Query: 1159 DRCARGHSQEFPTCLQCHLCFDQWDHTISSLSKAVQGLMRLAANMEDKRETLPVCEADFK 1218
+ A C C++Q + + +Q + L + + +P E
Sbjct: 603 EHGA----------FSCPACYNQVKIQMDQFMQQLQRMEALISKAQGGDGVVPDTE---- 648
Query: 1219 DLRGNVSEIER----ILKHPVFPSGKFLKVKDYHDSVRRQIMQLNEQLKAVYEFQDLKDT 1274
L G + + E+ IL+ G + VR Q +L DLK T
Sbjct: 649 -LEGRMQQAEQALQDILRDAQISEGASRSLGLQLAKVRSQENSYQSRL------DDLKMT 701
Query: 1275 IERAK----------NEADLLLEDLQEEIDLQSSVLNASIADSSENIKKYYHISSSAEKK 1324
+ER + + L+ +Q + + L + +S++ S A++
Sbjct: 702 VERVRALGSQYQNRVRDTHRLITQMQLSLAESEASLGNTNIPASDHYVGPNGFKSLAQEA 761
Query: 1325 INETSSTINTSANTRNDLLTILDTLTSKGNLSLERLKQIKIPDIQILNEKVCGDPGNVPC 1384
S + +++N + LT SK LSL R + L+E V G+
Sbjct: 762 TRLAESHVESASNM--EQLTRETEDYSKQALSLVR---------KALHEGVGSGSGSP-- 808
Query: 1385 VPLPCGGALCTGRKGHRKCRGPGCHGSLTLSTNALQKAQEAKSIIRNLDKQVRGLKNQIE 1444
GA+ G ++K ++ KS+ + L ++ Q E
Sbjct: 809 -----DGAVVQG---------------------LVEKLEKTKSLAQQLTREA----TQAE 838
Query: 1445 SISEQAEVSKNNALQLREKLGNIRNQSDSEEENINLFIKKVKNFLLEENVPPEDIEKVAN 1504
+A+ S ++L+L + + ++ SD ++F +EE + I++ A+
Sbjct: 839 I---EADRSYQHSLRLLDSVSRLQGVSD-------------QSFQVEE---AKRIKQKAD 879
Query: 1505 GVLDIHLPIPSQNLTDELVKIQKHMQLCEDYRTDENRLNEEADGAQKLLVKAKAAEKAAN 1564
+ + + +HM ++++ + L + AQ+LL K+ + ++
Sbjct: 880 SLSSL---------------VTRHM---DEFKRTQKNLGNWKEEAQQLLQNGKSGREKSD 921
Query: 1565 ILLNLDKTLNQLQQAQITQGRANSTITQLTANITKIKKNVLQAENQTREMKSELELAKQR 1624
LL+ Q ++ G N+T ++ + + +++ LQ +N+ E + E K+
Sbjct: 922 QLLSRANLAKSRAQEALSMG--NATFYEVESILKNLREFDLQVDNRKAEAE---EAMKRL 976
Query: 1625 SGLEDGLSLLQTKLQRHQDHAVNAKVQAESAQHQAGSLEKEFVELKKQYAILQRKTSTTG 1684
S + +S K Q+ + +A A+ A++ AG + E++++ L + + T
Sbjct: 977 SYISQKVSDASDKTQQAERALGSAAADAQRAKNGAGEALEISSEIEQEIGSLNLEANVTA 1036
Query: 1685 LTKETLGK-VKQLKDAAEKLAGDTEAK 1710
+ K + LK ++ G+ E K
Sbjct: 1037 DGALAMEKGLASLKSEMREVEGELERK 1063
Score = 114 bits (286), Expect = 6e-25
Identities = 62/183 (33%), Positives = 90/183 (49%), Gaps = 27/183 (14%)
Query: 332 CSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYA 391
C CN S +C FD + +G +G C +C NT+G HC++C+ FYR +
Sbjct: 28 CDCNGKSRQCIFDRELHRQTG--NGFRCLNCNDNTDGIHCEKCKNGFYRHRERD-----R 80
Query: 392 CIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHY-----GLSA 446
C+PC C+ G++S A +G+C CK V GA+CD+C P + G +
Sbjct: 81 CLPCNCNSKGSLS----------ARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQ 130
Query: 447 TDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGL-GNHLHGCSP 505
L CDC+P G + D G+C+C VTG C+ C GY+ L G + GC+
Sbjct: 131 DQRLLDSKCDCDPAG----IAGPCDAGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQ 186
Query: 506 CDC 508
C C
Sbjct: 187 CFC 189
Score = 113 bits (283), Expect = 1e-24
Identities = 81/237 (34%), Positives = 110/237 (46%), Gaps = 33/237 (13%)
Query: 787 QCQCKPLVVGRCCDRCSTG----SYDLGHHG-CHPCHCHPQGSKDTVCDQVTGQCPCHGE 841
QC C G+ C C++G S LG G C PC+C G+ CD TG C E
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA----CDPDTGDCYSGDE 436
Query: 842 VSGRRCDRCLAGYFGFP----SCHPCPC-NRFAELCDPETGS--CFNCGGFTTGRNCERC 894
C C G++ P SC PCPC N F+ PET C NC TG CE C
Sbjct: 437 NPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELC 496
Query: 895 IDGYYGNP----SSGQPCRPCLCPD--DPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQ 948
DGY+G+P +PC+PC C + DPS+ + +C + + C+ G
Sbjct: 497 ADGYFGDPFGEHGPVRPCQPCQCNNNVDPSA----SGNCDR---LTGRCLKCIHNTAGIY 549
Query: 949 CGECSTGFYGNPRISGAPCQPC-ACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQ 1004
C +C G++G+P ++ P C ACN N ++P C R G C+ C G NC+
Sbjct: 550 CDQCKAGYFGDP-LAPNPADKCRACNCNPMGSEPVGC-RSDGTCV-CKPGFGGPNCE 603
Score = 96.3 bits (238), Expect = 2e-19
Identities = 60/177 (33%), Positives = 75/177 (42%), Gaps = 31/177 (17%)
Query: 970 CACNNNID--VTDPESCSRVTGE---CLRCLHNTQGANCQLCKPGHYGSALNQTCRRCSC 1024
C CN + D E R TG CL C NT G +C+ CK G Y C C+C
Sbjct: 28 CDCNGKSRQCIFDRE-LHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNC 86
Query: 1025 HASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCADGYWNLVPGRGC------- 1077
++ G C +G C C P VTG CDRC G+ +++ GC
Sbjct: 87 NSKGSLSARCDN----------SGRCSCKPGVTGARCDRCLPGF-HMLTDAGCTQDQRLL 135
Query: 1078 -QSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSECQENYY---GDPPGRCIPCDC 1130
CDCDP + CD G+C CK G+RC C+ YY G P C C C
Sbjct: 136 DSKCDCDP-AGIAGPCD--AGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189
Score = 91.7 bits (226), Expect = 6e-18
Identities = 64/202 (31%), Positives = 89/202 (44%), Gaps = 43/202 (21%)
Query: 262 RGSCFCNGHASEC---RPMQKMRGDVFSPPGMVHGQCV-CQHNTDGPNCERCKDFFQDAP 317
R C CNG + +C R + + G+ F +C+ C NTDG +CE+CK+ F
Sbjct: 25 REVCDCNGKSRQCIFDRELHRQTGNGF--------RCLNCNDNTDGIHCEKCKNGFYRHR 76
Query: 318 WRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPL 377
R + C C+CNS S L++ + G C C+ G CDRC P
Sbjct: 77 ER-------DRCLPCNCNSKGS---------LSARCDNSGRCS-CKPGVTGARCDRCLPG 119
Query: 378 FYR--DPLKTISDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCD 435
F+ D T C+CDP G G C AG+C+CK V G +CD
Sbjct: 120 FHMLTDAGCTQDQRLLDSKCDCDPAGI--AGPCD----------AGRCVCKPAVTGERCD 167
Query: 436 QCKPNHYGLSATDPLGCQPCDC 457
+C+ +Y L +P GC C C
Sbjct: 168 RCRSGYYNLDGGNPEGCTQCFC 189
Score = 90.5 bits (223), Expect = 1e-17
Identities = 75/266 (28%), Positives = 100/266 (37%), Gaps = 59/266 (22%)
Query: 294 QCVCQHNTDGPNCERCKDFFQDAPWRPAADLQD-NACRSCSCNSHSSRCHFDMTTYLASG 352
QC+C G C+ C ++ R +A L C C+C
Sbjct: 381 QCICPVGYKGQFCQDCASGYK----RDSARLGPFGTCIPCNCQG---------------- 420
Query: 353 GLSGGVCE----DCQHNTEGQ--HCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGG 406
GG C+ DC E C C FY DP DP +C PC C G
Sbjct: 421 ---GGACDPDTGDCYSGDENPDIECADCPIGFYNDP----HDPRSCKPCPCH------NG 467
Query: 407 ICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLG-------CQPCDCNP 459
S V C V GA+C+ C ++G DP G CQPC CN
Sbjct: 468 FSCSVMPETEEVVCNNC--PPGVTGARCELCADGYFG----DPFGEHGPVRPCQPCQCNN 521
Query: 460 -LGSLPFLTCDVDTGQCL-CLSYVTGAHCEECTVGYWG---LGNHLHGCSPCDCDIGGAY 514
+ CD TG+CL C+ G +C++C GY+G N C C+C+ G+
Sbjct: 522 NVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSE 581
Query: 515 SNVCSPKNGQCECRPHVTGRSCSEPA 540
C +G C C+P G +C A
Sbjct: 582 PVGCR-SDGTCVCKPGFGGPNCEHGA 606
Score = 85.5 bits (210), Expect = 4e-16
Identities = 49/162 (30%), Positives = 74/162 (45%), Gaps = 20/162 (12%)
Query: 1052 CLPNVTGLACDRCADGYWNLVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCS 1111
C N G+ C++C +G++ C C+C+ + S S+ CD +G+C CK G G RC
Sbjct: 56 CNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDN-SGRCSCKPGVTGARCD 114
Query: 1112 ECQENYYGDPPGRCIP--------CDCNRAGTQKPICDPDTGMCRCREGVSGQRCDRCAR 1163
C ++ C CDC+ AG P D G C C+ V+G+RCDRC
Sbjct: 115 RCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPC---DAGRCVCKPAVTGERCDRCRS 171
Query: 1164 GH----SQEFPTCLQCHLCFDQWDHTISSLSKAVQGLMRLAA 1201
G+ C QC C+ H+ S S A + ++ +
Sbjct: 172 GYYNLDGGNPEGCTQC-FCY---GHSASCRSSAEYSVHKITS 209
Score = 82.4 bits (202), Expect = 4e-15
Identities = 48/157 (30%), Positives = 71/157 (45%), Gaps = 17/157 (10%)
Query: 764 DGAVACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHGC--------H 815
D + C C+ +GS+ + C G+C CKP V G CDRC G + L GC
Sbjct: 79 DRCLPCNCNSKGSLSARCDN-SGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDS 137
Query: 816 PCHCHPQGSKDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFPSCHPCPCNRFAELCDPE 875
C C P G CD G+C C V+G RCDRC +GY+ +P C + C
Sbjct: 138 KCDCDPAGIAGP-CD--AGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQC--FCYGH 192
Query: 876 TGSCFNCGGFTTGR---NCERCIDGYYGNPSSGQPCR 909
+ SC + ++ + + +DG+ +G P +
Sbjct: 193 SASCRSSAEYSVHKITSTFHQDVDGWKAVQRNGSPAK 229
Score = 81.6 bits (200), Expect = 6e-15
Identities = 50/132 (37%), Positives = 66/132 (50%), Gaps = 18/132 (13%)
Query: 422 QCL-CKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSY 480
+CL C +N +G C++CK Y D C PC+CN GSL CD ++G+C C
Sbjct: 52 RCLNCNDNTDGIHCEKCKNGFYRHRERDR--CLPCNCNSKGSLS-ARCD-NSGRCSCKPG 107
Query: 481 VTGAHCEECTVGYWGLGNHLHGC--------SPCDCDIGGAYSNVCSPKNGQCECRPHVT 532
VTGA C+ C G+ L + GC S CDCD G + C G+C C+P VT
Sbjct: 108 VTGARCDRCLPGFHMLTDA--GCTQDQRLLDSKCDCDPAGI-AGPCDA--GRCVCKPAVT 162
Query: 533 GRSCSEPAPGYF 544
G C GY+
Sbjct: 163 GERCDRCRSGYY 174
Score = 80.1 bits (196), Expect = 2e-14
Identities = 63/228 (27%), Positives = 86/228 (37%), Gaps = 41/228 (17%)
Query: 269 GHASECRPMQKMRGDVFSPPGMVHGQCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNA 328
G C P G P G C C C F + P P +
Sbjct: 408 GPFGTCIPCNCQGGGACDPDT---GDCYSGDENPDIECADCPIGFYNDPHDP------RS 458
Query: 329 CRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISD 388
C+ C C++ S T + VC +C G C+ C ++ DP
Sbjct: 459 CKPCPCHNGFSCSVMPETEEV--------VCNNCPPGVTGARCELCADGYFGDPFGEHGP 510
Query: 389 PYACIPCEC--DPDGTISGGICVSHSDPALGSVAGQCL-CKENVEGAKCDQCKPNHYGLS 445
C PC+C + D + SG + G+CL C N G CDQCK ++G
Sbjct: 511 VRPCQPCQCNNNVDPSASGN---------CDRLTGRCLKCIHNTAGIYCDQCKAGYFG-- 559
Query: 446 ATDPLG------CQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCE 487
DPL C+ C+CNP+GS P + C D G C+C G +CE
Sbjct: 560 --DPLAPNPADKCRACNCNPMGSEP-VGCRSD-GTCVCKPGFGGPNCE 603
Score = 69.3 bits (168), Expect = 3e-11
Identities = 42/129 (32%), Positives = 55/129 (42%), Gaps = 8/129 (6%)
Query: 422 QCLCKENVEGAKCDQCKPNHYGLSAT-DPLG-CQPCDCNPLGSLPFLTCDVDTGQCLCLS 479
QC+C +G C C + SA P G C PC+C G+ CD DTG C
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA-----CDPDTGDCYSGD 435
Query: 480 YVTGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYSNVCSPKNGQC-ECRPHVTGRSCSE 538
C +C +G++ + C PC C G + S + + C C P VTG C
Sbjct: 436 ENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCEL 495
Query: 539 PAPGYFFAP 547
A GYF P
Sbjct: 496 CADGYFGDP 504
Score = 62.4 bits (150), Expect = 4e-09
Identities = 42/135 (31%), Positives = 56/135 (41%), Gaps = 18/135 (13%)
Query: 1045 PVTGA-------CPCLPNVTGLACDRCADGY----WNLVPGRGCQSCDCDPRTSQSSHCD 1093
PV+GA C C G C CA GY L P C C+C CD
Sbjct: 370 PVSGAPAPWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNC----QGGGACD 425
Query: 1094 QLTGQCPCKLGYGGKRCSECQENYYGDP--PGRCIPCDCNRAGTQKPICDPDTGMC-RCR 1150
TG C C++C +Y DP P C PC C+ + + + + +C C
Sbjct: 426 PDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCP 485
Query: 1151 EGVSGQRCDRCARGH 1165
GV+G RC+ CA G+
Sbjct: 486 PGVTGARCELCADGY 500
Score = 60.5 bits (145), Expect = 1e-08
Identities = 49/187 (26%), Positives = 74/187 (39%), Gaps = 38/187 (20%)
Query: 863 CPCNRFAELC------DPETGS---CFNCGGFTTGRNCERCIDGYYGNPSSGQPCRPCLC 913
C CN + C +TG+ C NC T G +CE+C +G+Y + + C PC C
Sbjct: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDR-CLPCNC 86
Query: 914 PDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPC------ 967
+S + C + C+C G TG +C C GF+ ++ A C
Sbjct: 87 ----NSKGSLSARC-----DNSGRCSCKPGVTGARCDRCLPGFH---MLTDAGCTQDQRL 134
Query: 968 --QPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQLCKPGHYG--SALNQTCRRCS 1023
C C + + P C G C+ C G C C+ G+Y + C +C
Sbjct: 135 LDSKCDC-DPAGIAGP--CD--AGRCV-CKPAVTGERCDRCRSGYYNLDGGNPEGCTQCF 188
Query: 1024 CHASGVS 1030
C+ S
Sbjct: 189 CYGHSAS 195
Score = 57.8 bits (138), Expect = 9e-08
Identities = 43/149 (28%), Positives = 59/149 (39%), Gaps = 29/149 (19%)
Query: 838 CHGEVSGRRCDRCLAGYFGF---PSCHPCPCNRFAEL---CDPETGSCFNCGGFTTGRNC 891
C+ G C++C G++ C PC CN L CD +G C +C TG C
Sbjct: 56 CNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCD-NSGRC-SCKPGVTGARC 113
Query: 892 ERCIDGYYGNPSSG----QPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGT 947
+RC+ G++ +G Q C DP+ A C C C TG
Sbjct: 114 DRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAG---IAGPCDAGR------CVCKPAVTGE 164
Query: 948 QCGECSTGFY----GNPRISGAPCQPCAC 972
+C C +G+Y GNP C C C
Sbjct: 165 RCDRCRSGYYNLDGGNPE----GCTQCFC 189
Score = 55.5 bits (132), Expect = 5e-07
Identities = 30/86 (34%), Positives = 36/86 (41%), Gaps = 9/86 (10%)
Query: 1098 QCPCKLGYGGKRCSECQENYYGD-----PPGRCIPCDCNRAGTQKPICDPDTGMCRCREG 1152
QC C +GY G+ C +C Y D P G CIPC+C G CDPDTG C +
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA----CDPDTGDCYSGDE 436
Query: 1153 VSGQRCDRCARGHSQEFPTCLQCHLC 1178
C C G + C C
Sbjct: 437 NPDIECADCPIGFYNDPHDPRSCKPC 462
Score = 54.7 bits (130), Expect = 8e-07
Identities = 32/95 (33%), Positives = 45/95 (47%), Gaps = 8/95 (8%)
Query: 455 CDCNPLGSLPFLTCDV--DTG---QCL-CLSYVTGAHCEECTVGYWGLGNHLHGCSPCDC 508
CDCN ++ TG +CL C G HCE+C G++ C PC+C
Sbjct: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYR-HRERDRCLPCNC 86
Query: 509 DIGGAYSNVCSPKNGQCECRPHVTGRSCSEPAPGY 543
+ G+ S C +G+C C+P VTG C PG+
Sbjct: 87 NSKGSLSARCD-NSGRCSCKPGVTGARCDRCLPGF 120
Score = 49.3 bits (116), Expect = 3e-05
Identities = 29/99 (29%), Positives = 42/99 (42%), Gaps = 10/99 (10%)
Query: 769 CKCHPQGSVGSSCSRLGGQC-QCKPLVVGRCCDRCSTGSYD-----LGHHGCHPCHCHPQ 822
C + S +C RL G+C +C G CD+C G + C C+C+P
Sbjct: 519 CNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPM 578
Query: 823 GSKDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFPSCH 861
GS+ C + G C C G C+ G F P+C+
Sbjct: 579 GSEPVGC-RSDGTCVCKPGFGGPNCEH---GAFSCPACY 613
Score = 34.3 bits (77), Expect = 1.1
Identities = 14/49 (28%), Positives = 21/49 (42%), Gaps = 5/49 (10%)
Query: 293 GQCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRC 341
G+CVC+ G C+RC+ + + C C C HS+ C
Sbjct: 153 GRCVCKPAVTGERCDRCRSGYYNLDGG-----NPEGCTQCFCYGHSASC 196
Score = 32.3 bits (72), Expect = 4.2
Identities = 19/55 (34%), Positives = 22/55 (40%), Gaps = 9/55 (16%)
Query: 764 DGAVACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHGCHPCH 818
D AC C+P GS C R G C CKP G C+ G C C+
Sbjct: 568 DKCRACNCNPMGSEPVGC-RSDGTCVCKPGFGGPNCEH--------GAFSCPACY 613
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.435
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 77,470,595
Number of Sequences: 37866
Number of extensions: 4184183
Number of successful extensions: 22093
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 90
Number of HSP's successfully gapped in prelim test: 800
Number of HSP's that attempted gapping in prelim test: 11570
Number of HSP's gapped (non-prelim): 4976
length of query: 1761
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1645
effective length of database: 13,855,062
effective search space: 22791576990
effective search space used: 22791576990
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.