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Search of human proteins with 14327896
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14327896 cyclin B1 [Homo sapiens]
(433 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14327896 cyclin B1 [Homo sapiens] 860 0.0
gi|4757930 cyclin B2 [Homo sapiens] 392 e-109
gi|90669307 cyclin B3 isoform 3 [Homo sapiens] 184 1e-46
gi|4502613 cyclin A [Homo sapiens] 174 1e-43
gi|161377472 cyclin A1 isoform c [Homo sapiens] 172 4e-43
gi|161377470 cyclin A1 isoform c [Homo sapiens] 172 4e-43
gi|161377468 cyclin A1 isoform b [Homo sapiens] 172 4e-43
gi|4502611 cyclin A1 isoform a [Homo sapiens] 172 4e-43
gi|16306525 cyclin B3 isoform 1 [Homo sapiens] 126 3e-29
gi|242247025 cyclin N-terminal domain containing 2 isoform 2 [Ho... 101 1e-21
gi|17318559 cyclin E1 isoform 1 [Homo sapiens] 100 3e-21
gi|17318561 cyclin E1 isoform 2 [Homo sapiens] 100 3e-21
gi|17318565 cyclin E2 [Homo sapiens] 97 4e-20
gi|153791755 cyclin domain containing [Homo sapiens] 92 1e-18
gi|118572588 cyclin F [Homo sapiens] 89 8e-18
gi|16950655 cyclin D1 [Homo sapiens] 82 7e-16
gi|4502619 cyclin D3 isoform 2 [Homo sapiens] 79 8e-15
gi|4502617 cyclin D2 [Homo sapiens] 70 4e-12
gi|197276674 cyclin J isoform 1 [Homo sapiens] 58 2e-08
gi|209862835 cyclin D3 isoform 1 [Homo sapiens] 56 7e-08
gi|5031703 Ras-GTPase-activating protein SH3-domain-binding prot... 54 4e-07
gi|38327552 Ras-GTPase-activating protein SH3-domain-binding pro... 54 4e-07
gi|89886237 cyclin I family, member 2 [Homo sapiens] 50 3e-06
gi|5802992 cyclin I [Homo sapiens] 49 1e-05
gi|5730045 solute carrier family 16, member 2 [Homo sapiens] 47 4e-05
gi|24307909 ral guanine nucleotide dissociation stimulator isofo... 46 6e-05
gi|108796058 ral guanine nucleotide dissociation stimulator isof... 46 6e-05
gi|4505419 nucleolar protein 3 [Homo sapiens] 46 8e-05
gi|110349719 titin isoform N2-A [Homo sapiens] 45 1e-04
gi|41281612 zinc finger protein 828 [Homo sapiens] 45 1e-04
>gi|14327896 cyclin B1 [Homo sapiens]
Length = 433
Score = 860 bits (2222), Expect = 0.0
Identities = 433/433 (100%), Positives = 433/433 (100%)
Query: 1 MALRVTRNSKINAENKAKINMAGAKRVPTAPAATSKPGLRPRTALGDIGNKVSEQLQAKM 60
MALRVTRNSKINAENKAKINMAGAKRVPTAPAATSKPGLRPRTALGDIGNKVSEQLQAKM
Sbjct: 1 MALRVTRNSKINAENKAKINMAGAKRVPTAPAATSKPGLRPRTALGDIGNKVSEQLQAKM 60
Query: 61 PMKKEAKPSATGKVIDKKLPKPLEKVPMLVPVPVSEPVPEPEPEPEPEPVKEEKLSPEPI 120
PMKKEAKPSATGKVIDKKLPKPLEKVPMLVPVPVSEPVPEPEPEPEPEPVKEEKLSPEPI
Sbjct: 61 PMKKEAKPSATGKVIDKKLPKPLEKVPMLVPVPVSEPVPEPEPEPEPEPVKEEKLSPEPI 120
Query: 121 LVDTASPSPMETSGCAPAEEDLCQAFSDVILAVNDVDAEDGADPNLCSEYVKDIYAYLRQ 180
LVDTASPSPMETSGCAPAEEDLCQAFSDVILAVNDVDAEDGADPNLCSEYVKDIYAYLRQ
Sbjct: 121 LVDTASPSPMETSGCAPAEEDLCQAFSDVILAVNDVDAEDGADPNLCSEYVKDIYAYLRQ 180
Query: 181 LEEEQAVRPKYLLGREVTGNMRAILIDWLVQVQMKFRLLQETMYMTVSIIDRFMQNNCVP 240
LEEEQAVRPKYLLGREVTGNMRAILIDWLVQVQMKFRLLQETMYMTVSIIDRFMQNNCVP
Sbjct: 181 LEEEQAVRPKYLLGREVTGNMRAILIDWLVQVQMKFRLLQETMYMTVSIIDRFMQNNCVP 240
Query: 241 KKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNTYTKHQIRQMEMKILRALNFGLGRP 300
KKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNTYTKHQIRQMEMKILRALNFGLGRP
Sbjct: 241 KKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNTYTKHQIRQMEMKILRALNFGLGRP 300
Query: 301 LPLHFLRRASKIGEVDVEQHTLAKYLMELTMLDYDMVHFPPSQIAAGAFCLALKILDNGE 360
LPLHFLRRASKIGEVDVEQHTLAKYLMELTMLDYDMVHFPPSQIAAGAFCLALKILDNGE
Sbjct: 301 LPLHFLRRASKIGEVDVEQHTLAKYLMELTMLDYDMVHFPPSQIAAGAFCLALKILDNGE 360
Query: 361 WTPTLQHYLSYTEESLLPVMQHLAKNVVMVNQGLTKHMTVKNKYATSKHAKISTLPQLNS 420
WTPTLQHYLSYTEESLLPVMQHLAKNVVMVNQGLTKHMTVKNKYATSKHAKISTLPQLNS
Sbjct: 361 WTPTLQHYLSYTEESLLPVMQHLAKNVVMVNQGLTKHMTVKNKYATSKHAKISTLPQLNS 420
Query: 421 ALVQDLAKAVAKV 433
ALVQDLAKAVAKV
Sbjct: 421 ALVQDLAKAVAKV 433
>gi|4757930 cyclin B2 [Homo sapiens]
Length = 398
Score = 392 bits (1008), Expect = e-109
Identities = 210/387 (54%), Positives = 269/387 (69%), Gaps = 28/387 (7%)
Query: 42 RTALGDIGNKVSEQLQAKMPMKKEAKPSATGKVIDKKLPKPLEKVPMLVPVPVSEPVPEP 101
RT L +IGN+V+ + + K+A+ + KVP+ P + +
Sbjct: 32 RTVLEEIGNRVTTRAAQ---VAKKAQNT---------------KVPVQ-PTKTTNVNKQL 72
Query: 102 EPEPEPEPVKEEKLSPEPILVDTASPSPMETSGCAPAEEDLCQAFSDVILA-VNDVDAED 160
+P +PV+ EKL+P+ SP+P + S EE+LCQAFSD +L + D+D ED
Sbjct: 73 KPTASVKPVQMEKLAPKG-----PSPTPEDVS---MKEENLCQAFSDALLCKIEDIDNED 124
Query: 161 GADPNLCSEYVKDIYAYLRQLEEEQAVRPKYLLGREVTGNMRAILIDWLVQVQMKFRLLQ 220
+P LCS+YVKDIY YLRQLE Q++ P +L GR++ G MRAIL+DWLVQV KFRLLQ
Sbjct: 125 WENPQLCSDYVKDIYQYLRQLEVLQSINPHFLDGRDINGRMRAILVDWLVQVHSKFRLLQ 184
Query: 221 ETMYMTVSIIDRFMQNNCVPKKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNTYTKH 280
ET+YM V I+DRF+Q V +K LQLVG+TA+ +ASKYEEM+ P I DF ++TDN YT
Sbjct: 185 ETLYMCVGIMDRFLQVQPVSRKKLQLVGITALLLASKYEEMFSPNIEDFVYITDNAYTSS 244
Query: 281 QIRQMEMKILRALNFGLGRPLPLHFLRRASKIGEVDVEQHTLAKYLMELTMLDYDMVHFP 340
QIR+ME IL+ L F LGRPLPLHFLRRASK GEVDVEQHTLAKYLMELT++DYDMVH+
Sbjct: 245 QIREMETLILKELKFELGRPLPLHFLRRASKAGEVDVEQHTLAKYLMELTLIDYDMVHYH 304
Query: 341 PSQIAAGAFCLALKILDNGEWTPTLQHYLSYTEESLLPVMQHLAKNVVMVNQGLTKHMTV 400
PS++AA A CL+ K+L G+W Q+Y YTE +L VMQH+AKNVV VN+ LTK + +
Sbjct: 305 PSKVAAAASCLSQKVLGQGKWNLKQQYYTGYTENEVLEVMQHMAKNVVKVNENLTKFIAI 364
Query: 401 KNKYATSKHAKISTLPQLNSALVQDLA 427
KNKYA+SK KIS +PQLNS V+DLA
Sbjct: 365 KNKYASSKLLKISMIPQLNSKAVKDLA 391
>gi|90669307 cyclin B3 isoform 3 [Homo sapiens]
Length = 1395
Score = 184 bits (468), Expect = 1e-46
Identities = 121/414 (29%), Positives = 211/414 (50%), Gaps = 26/414 (6%)
Query: 29 TAPAA-TSKPGLRPRTALGDIGNKVSEQLQAKMPMKKEAKPSATGKVIDKKLPKPLEKVP 87
TAP + TSK + T++G G ++E + + KP+ TGK + K P L++ P
Sbjct: 980 TAPESITSKSSIATMTSVGKSGT-INEAFLFEDMITLNEKPT-TGKELSFKEPLALQESP 1037
Query: 88 MLVPVPVSEP--VPEPEPEPEPEPVKEEKLSPEPILVDTASPSPMETSGCAPAEEDLCQA 145
E +P+ P E ++ + + S T+ E C++
Sbjct: 1038 TCKEDTFLETFLIPQIGTSPYVFSTTPESITEKSSIATMTSVGKSRTT----TESSACES 1093
Query: 146 FSDV------------ILAVNDVDAEDGADPNLCSEYVKDIYAYLRQLEEEQAVRPKYLL 193
SD I D+D ED +DP+ Y K+I++Y+++ EEQ + Y+
Sbjct: 1094 ASDKPVSPQAKGTPKEITPREDID-EDSSDPSFNPMYAKEIFSYMKE-REEQFILTDYMN 1151
Query: 194 GR-EVTGNMRAILIDWLVQVQMKFRLLQETMYMTVSIIDRFMQNNCVPKKMLQLVGVTAM 252
+ E+T +MRAIL+DWLV+VQ+ F + ET+Y+ V ++D ++ K LQL+G TA
Sbjct: 1152 RQIEITSDMRAILVDWLVEVQVSFEMTHETLYLAVKLVDLYLMKAVCKKDKLQLLGATAF 1211
Query: 253 FIASKYEEMYPPEIGDFAFVTDNTYTKHQIRQMEMKILRALNFGLGRPLPLHFLRRASKI 312
IA+K+EE P + DF ++ D+ Y + ++ ME+ IL L + P+ HFLRR ++
Sbjct: 1212 MIAAKFEEHNSPRVDDFVYICDDNYQRSEVLSMEINILNVLKCDINIPIAYHFLRRYARC 1271
Query: 313 GEVDVEQHTLAKYLMELTMLDYDMVHFPPSQIAAGAFCLALKILDNGEWTPTLQHYLSYT 372
+++ TL++Y+ E+T+ +Y V S++AA + LAL + G W P L+HY Y+
Sbjct: 1272 IHTNMKTLTLSRYICEMTLQEYHYVQEKASKLAAASLLLALYMKKLGYWVPFLEHYSGYS 1331
Query: 373 EESLLPVMQHLAKNVVMVNQGLTKHMTVKNKYATSKHAKISTLPQLNSALVQDL 426
L P+++ L K + + K V KY+ +++ +P L+ ++++
Sbjct: 1332 ISELHPLVRQLNKLLTFSSYDSLK--AVYYKYSHPVFFEVAKIPALDMLKLEEI 1383
>gi|4502613 cyclin A [Homo sapiens]
Length = 432
Score = 174 bits (441), Expect = 1e-43
Identities = 124/397 (31%), Positives = 201/397 (50%), Gaps = 16/397 (4%)
Query: 28 PTAPAATSKPGLRPRTALGDIGNKVSEQLQAKMPMKKEAKPSATGKVIDKKLPKPLEKVP 87
P A +P R A+ GN Q + P + P V D+ + P K
Sbjct: 35 PEKAAPVQQPRTRAALAVLKSGNPRG-LAQQQRPKTRRVAPLKDLPVNDEHVTVPPWKAN 93
Query: 88 MLVPVPVSEPVPEPEPEPEPEPVKEEKLSPEPILV-DTASPSPMETSGCAPAEEDLCQAF 146
P + V E E E + +P + +K+ E L ++A P P + + +F
Sbjct: 94 SKQPA-FTIHVDEAEKEAQKKPAESQKIEREDALAFNSAISLPGPRKPLVPLDYPMDGSF 152
Query: 147 S-----DVILAVNDVDAEDGADPNLCSEYVKDIYAYLRQLEEEQAVRPKYLLGR-EVTGN 200
D+ + + D E N +Y +DI+ YLR++E + + Y+ + ++T +
Sbjct: 153 ESPHTMDMSIVLED---EKPVSVNEVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNS 209
Query: 201 MRAILIDWLVQVQMKFRLLQETMYMTVSIIDRFMQNNCVPKKMLQLVGVTAMFIASKYEE 260
MRAIL+DWLV+V +++L ET+++ V+ IDRF+ + V + LQLVG AM +ASK+EE
Sbjct: 210 MRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEE 269
Query: 261 MYPPEIGDFAFVTDNTYTKHQIRQMEMKILRALNFGLGRPLPLHFLRRASKIGE-VDVEQ 319
+YPPE+ +F ++TD+TYTK Q+ +ME +L+ L F L P FL + + + +
Sbjct: 270 IYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKV 329
Query: 320 HTLAKYLMELTMLDYD-MVHFPPSQIAAGAFCLALKILDNGEWTPTLQHYLSYTEESLLP 378
+LA +L EL+++D D + + PS IA AF LAL + W +L YT ESL P
Sbjct: 330 ESLAMFLGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPESLIRKTGYTLESLKP 389
Query: 379 VMQHLAKNVVMVNQGLTKHMTVKNKYATSKHAKISTL 415
+ L + + Q +++ KY SK+ +S L
Sbjct: 390 CLMDLHQTYLKAPQ--HAQQSIREKYKNSKYHGVSLL 424
>gi|161377472 cyclin A1 isoform c [Homo sapiens]
Length = 421
Score = 172 bits (437), Expect = 4e-43
Identities = 96/257 (37%), Positives = 149/257 (57%), Gaps = 4/257 (1%)
Query: 161 GADPNLCSEYVKDIYAYLRQLEEEQAVRPKYLLGR-EVTGNMRAILIDWLVQVQMKFRLL 219
G D +EY ++IY YLR+ E + Y+ + ++T MR IL+DWLV+V +++L
Sbjct: 158 GTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLR 217
Query: 220 QETMYMTVSIIDRFMQNNCVPKKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNTYTK 279
ET+Y+ V+ +DRF+ V + LQLVG AM +ASKYEE+YPPE+ +F ++TD+TYTK
Sbjct: 218 AETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTK 277
Query: 280 HQIRQMEMKILRALNFGLGRPLPLHFLRRASKIGEVDVEQHTLAKYLMELTMLDYD-MVH 338
Q+ +ME +L+ L F L P FL + + V V LAKY+ EL++L+ D +
Sbjct: 278 RQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLK 337
Query: 339 FPPSQIAAGAFCLALKILDNGEWTPTLQHYLSYTEESLLPVMQHLAKNVVMVNQGLTKHM 398
+ PS IAA AFCLA ++ W TL + Y+ ++P + L K + +
Sbjct: 338 YLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKAYLDIPH--RPQQ 395
Query: 399 TVKNKYATSKHAKISTL 415
++ KY SK+ +S +
Sbjct: 396 AIREKYKASKYLCVSLM 412
>gi|161377470 cyclin A1 isoform c [Homo sapiens]
Length = 421
Score = 172 bits (437), Expect = 4e-43
Identities = 96/257 (37%), Positives = 149/257 (57%), Gaps = 4/257 (1%)
Query: 161 GADPNLCSEYVKDIYAYLRQLEEEQAVRPKYLLGR-EVTGNMRAILIDWLVQVQMKFRLL 219
G D +EY ++IY YLR+ E + Y+ + ++T MR IL+DWLV+V +++L
Sbjct: 158 GTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLR 217
Query: 220 QETMYMTVSIIDRFMQNNCVPKKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNTYTK 279
ET+Y+ V+ +DRF+ V + LQLVG AM +ASKYEE+YPPE+ +F ++TD+TYTK
Sbjct: 218 AETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTK 277
Query: 280 HQIRQMEMKILRALNFGLGRPLPLHFLRRASKIGEVDVEQHTLAKYLMELTMLDYD-MVH 338
Q+ +ME +L+ L F L P FL + + V V LAKY+ EL++L+ D +
Sbjct: 278 RQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLK 337
Query: 339 FPPSQIAAGAFCLALKILDNGEWTPTLQHYLSYTEESLLPVMQHLAKNVVMVNQGLTKHM 398
+ PS IAA AFCLA ++ W TL + Y+ ++P + L K + +
Sbjct: 338 YLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKAYLDIPH--RPQQ 395
Query: 399 TVKNKYATSKHAKISTL 415
++ KY SK+ +S +
Sbjct: 396 AIREKYKASKYLCVSLM 412
>gi|161377468 cyclin A1 isoform b [Homo sapiens]
Length = 464
Score = 172 bits (437), Expect = 4e-43
Identities = 96/257 (37%), Positives = 149/257 (57%), Gaps = 4/257 (1%)
Query: 161 GADPNLCSEYVKDIYAYLRQLEEEQAVRPKYLLGR-EVTGNMRAILIDWLVQVQMKFRLL 219
G D +EY ++IY YLR+ E + Y+ + ++T MR IL+DWLV+V +++L
Sbjct: 201 GTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLR 260
Query: 220 QETMYMTVSIIDRFMQNNCVPKKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNTYTK 279
ET+Y+ V+ +DRF+ V + LQLVG AM +ASKYEE+YPPE+ +F ++TD+TYTK
Sbjct: 261 AETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTK 320
Query: 280 HQIRQMEMKILRALNFGLGRPLPLHFLRRASKIGEVDVEQHTLAKYLMELTMLDYD-MVH 338
Q+ +ME +L+ L F L P FL + + V V LAKY+ EL++L+ D +
Sbjct: 321 RQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLK 380
Query: 339 FPPSQIAAGAFCLALKILDNGEWTPTLQHYLSYTEESLLPVMQHLAKNVVMVNQGLTKHM 398
+ PS IAA AFCLA ++ W TL + Y+ ++P + L K + +
Sbjct: 381 YLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKAYLDIPH--RPQQ 438
Query: 399 TVKNKYATSKHAKISTL 415
++ KY SK+ +S +
Sbjct: 439 AIREKYKASKYLCVSLM 455
>gi|4502611 cyclin A1 isoform a [Homo sapiens]
Length = 465
Score = 172 bits (437), Expect = 4e-43
Identities = 96/257 (37%), Positives = 149/257 (57%), Gaps = 4/257 (1%)
Query: 161 GADPNLCSEYVKDIYAYLRQLEEEQAVRPKYLLGR-EVTGNMRAILIDWLVQVQMKFRLL 219
G D +EY ++IY YLR+ E + Y+ + ++T MR IL+DWLV+V +++L
Sbjct: 202 GTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLR 261
Query: 220 QETMYMTVSIIDRFMQNNCVPKKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNTYTK 279
ET+Y+ V+ +DRF+ V + LQLVG AM +ASKYEE+YPPE+ +F ++TD+TYTK
Sbjct: 262 AETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTK 321
Query: 280 HQIRQMEMKILRALNFGLGRPLPLHFLRRASKIGEVDVEQHTLAKYLMELTMLDYD-MVH 338
Q+ +ME +L+ L F L P FL + + V V LAKY+ EL++L+ D +
Sbjct: 322 RQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLK 381
Query: 339 FPPSQIAAGAFCLALKILDNGEWTPTLQHYLSYTEESLLPVMQHLAKNVVMVNQGLTKHM 398
+ PS IAA AFCLA ++ W TL + Y+ ++P + L K + +
Sbjct: 382 YLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKAYLDIPH--RPQQ 439
Query: 399 TVKNKYATSKHAKISTL 415
++ KY SK+ +S +
Sbjct: 440 AIREKYKASKYLCVSLM 456
>gi|16306525 cyclin B3 isoform 1 [Homo sapiens]
Length = 291
Score = 126 bits (317), Expect = 3e-29
Identities = 64/213 (30%), Positives = 117/213 (54%), Gaps = 2/213 (0%)
Query: 214 MKFRLLQETMYMTVSIIDRFMQNNCVPKKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVT 273
+ F + ET+Y+ V ++D ++ K LQL+G TA IA+K+EE P + DF ++
Sbjct: 69 VSFEMTHETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDFVYIC 128
Query: 274 DNTYTKHQIRQMEMKILRALNFGLGRPLPLHFLRRASKIGEVDVEQHTLAKYLMELTMLD 333
D+ Y + ++ ME+ IL L + P+ HFLRR ++ +++ TL++Y+ E+T+ +
Sbjct: 129 DDNYQRSEVLSMEINILNVLKCDINIPIAYHFLRRYARCIHTNMKTLTLSRYICEMTLQE 188
Query: 334 YDMVHFPPSQIAAGAFCLALKILDNGEWTPTLQHYLSYTEESLLPVMQHLAKNVVMVNQG 393
Y V S++AA + LAL + G W P L+HY Y+ L P+++ L K + +
Sbjct: 189 YHYVQEKASKLAAASLLLALYMKKLGYWVPFLEHYSGYSISELHPLVRQLNKLLTFSSYD 248
Query: 394 LTKHMTVKNKYATSKHAKISTLPQLNSALVQDL 426
K V KY+ +++ +P L+ ++++
Sbjct: 249 SLK--AVYYKYSHPVFFEVAKIPALDMLKLEEI 279
>gi|242247025 cyclin N-terminal domain containing 2 isoform 2 [Homo
sapiens]
Length = 307
Score = 101 bits (252), Expect = 1e-21
Identities = 62/189 (32%), Positives = 101/189 (53%), Gaps = 4/189 (2%)
Query: 169 EYVKDIYAYLRQLEEEQAVRPKYLLGREVTGNMRAILIDWLVQVQMKFRLLQETMYMTVS 228
EY DI+A + V P L R VT MRA+++DWLVQV L +T+Y+ V
Sbjct: 79 EYAGDIFAEVMVCR----VLPLRALPRAVTPEMRALVVDWLVQVHEYLGLAGDTLYLAVH 134
Query: 229 IIDRFMQNNCVPKKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNTYTKHQIRQMEMK 288
++D ++ V LQL+GV +F+A K EE PE ++ +++++ ++ + E +
Sbjct: 135 LLDSYLSAGRVRLHRLQLLGVACLFVACKMEECVLPEPAFLCLLSADSFSRAELLRAERR 194
Query: 289 ILRALNFGLGRPLPLHFLRRASKIGEVDVEQHTLAKYLMELTMLDYDMVHFPPSQIAAGA 348
IL L+F L P PL L + + + LA Y +EL++L+ + + P + AA A
Sbjct: 195 ILSRLDFRLHHPGPLLCLGLLAALAGSSPQVMLLATYFLELSLLEAEAAGWEPGRRAAAA 254
Query: 349 FCLALKILD 357
LA ++LD
Sbjct: 255 LSLAHRLLD 263
>gi|17318559 cyclin E1 isoform 1 [Homo sapiens]
Length = 410
Score = 100 bits (249), Expect = 3e-21
Identities = 66/188 (35%), Positives = 107/188 (56%), Gaps = 27/188 (14%)
Query: 177 YLRQ---LEEEQAVRPKYLLGREVTGNMRAILIDWLVQVQMKFRLLQETMYMTVSIIDRF 233
YLR LE+ ++PK MRAIL+DWL++V ++L +ET Y+ DR+
Sbjct: 127 YLRDQHFLEQHPLLQPK----------MRAILLDWLMEVCEVYKLHRETFYLAQDFFDRY 176
Query: 234 M--QNNCVPKKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNTYTKHQIRQMEMKILR 291
M Q N V K +LQL+G++++FIA+K EE+YPP++ FA+VTD + +I ME+ I++
Sbjct: 177 MATQENVV-KTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMK 235
Query: 292 ALNFGLGRPLPLHFLRRASKIGEV-DVEQHTLAKY----------LMELTMLDYDMVHFP 340
AL + L + +L ++ + D+ + L +Y L++L +LD D + FP
Sbjct: 236 ALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFP 295
Query: 341 PSQIAAGA 348
+AA A
Sbjct: 296 YGILAASA 303
>gi|17318561 cyclin E1 isoform 2 [Homo sapiens]
Length = 395
Score = 100 bits (249), Expect = 3e-21
Identities = 66/188 (35%), Positives = 107/188 (56%), Gaps = 27/188 (14%)
Query: 177 YLRQ---LEEEQAVRPKYLLGREVTGNMRAILIDWLVQVQMKFRLLQETMYMTVSIIDRF 233
YLR LE+ ++PK MRAIL+DWL++V ++L +ET Y+ DR+
Sbjct: 112 YLRDQHFLEQHPLLQPK----------MRAILLDWLMEVCEVYKLHRETFYLAQDFFDRY 161
Query: 234 M--QNNCVPKKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNTYTKHQIRQMEMKILR 291
M Q N V K +LQL+G++++FIA+K EE+YPP++ FA+VTD + +I ME+ I++
Sbjct: 162 MATQENVV-KTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMK 220
Query: 292 ALNFGLGRPLPLHFLRRASKIGEV-DVEQHTLAKY----------LMELTMLDYDMVHFP 340
AL + L + +L ++ + D+ + L +Y L++L +LD D + FP
Sbjct: 221 ALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFP 280
Query: 341 PSQIAAGA 348
+AA A
Sbjct: 281 YGILAASA 288
>gi|17318565 cyclin E2 [Homo sapiens]
Length = 404
Score = 96.7 bits (239), Expect = 4e-20
Identities = 63/183 (34%), Positives = 101/183 (55%), Gaps = 14/183 (7%)
Query: 182 EEEQAVRPKY--LLGREVTGNMRAILIDWLVQVQMKFRLLQETMYMTVSIIDRFM-QNNC 238
+E + V K+ +L ++ MR+IL+DWL++V + L +ET Y+ DRFM
Sbjct: 120 KESRYVHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKD 179
Query: 239 VPKKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNTYTKHQIRQMEMKILRALNF--- 295
+ K MLQL+G+T++FIASK EE+Y P++ +FA+VTD ++ I +ME+ IL+AL +
Sbjct: 180 INKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWELC 239
Query: 296 ------GLGRPLPLHFLRRASKIGEVDVEQHTLAK--YLMELTMLDYDMVHFPPSQIAAG 347
L L + L+ A K+ Q T + L++L +L D + F + A
Sbjct: 240 PVTIISWLNLFLQVDALKDAPKVLLPQYSQETFIQIAQLLDLCILAIDSLEFQYRILTAA 299
Query: 348 AFC 350
A C
Sbjct: 300 ALC 302
>gi|153791755 cyclin domain containing [Homo sapiens]
Length = 350
Score = 91.7 bits (226), Expect = 1e-18
Identities = 58/198 (29%), Positives = 100/198 (50%), Gaps = 12/198 (6%)
Query: 169 EYVKDIYAYLRQLEEEQAVRPKYLLGRE--VTGNMRAILIDWLVQVQMKFRLLQETMYMT 226
+Y + YA+ + +E P+ L R+ VT R L+ WL+ V +F L E++ +T
Sbjct: 100 DYGQSCYAFRKA--QESHFHPREALARQPQVTAESRCKLLSWLIPVHRQFGLSFESLCLT 157
Query: 227 VSIIDRFMQNNCVPKKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNTYTKHQIRQME 286
V+ +DRF+ V QL+GVT++ IA K E++PP + + +++ Q+ +E
Sbjct: 158 VNTLDRFLTTTPVAADCFQLLGVTSLLIACKQVEVHPPRVKQLLALCCGAFSRQQLCNLE 217
Query: 287 MKILRALNFGLGRP----LPLHFLRRASKIGEVD----VEQHTLAKYLMELTMLDYDMVH 338
+L L+F LG P HF + G+ + +E LA+ + EL++ DY
Sbjct: 218 CIVLHKLHFTLGAPTISFFLEHFTHARVEAGQAEASEALEAQALARGVAELSLADYAFTS 277
Query: 339 FPPSQIAAGAFCLALKIL 356
+ PS +A LA ++L
Sbjct: 278 YSPSLLAICCLALADRML 295
>gi|118572588 cyclin F [Homo sapiens]
Length = 786
Score = 89.0 bits (219), Expect = 8e-18
Identities = 60/228 (26%), Positives = 112/228 (49%), Gaps = 9/228 (3%)
Query: 161 GADPNLCSEYVKDIYAYLRQLEEEQAVRPKYLLGREVTGNMRAILIDWLVQVQMKFRLLQ 220
G + SE V ++ + + ++Q + + + + MR ILIDWLV+V
Sbjct: 273 GLEVRASSEIVCQLFQASQAVSKQQV----FSVQKGLNDTMRYILIDWLVEVATMKDFTS 328
Query: 221 ETMYMTVSIIDRFMQNNCVPKKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNTYTKH 280
+++TV +DR+++ VP+ LQL+G+ M I +++ I + ++TDNTY
Sbjct: 329 LCLHLTVECVDRYLRRRLVPRYRLQLLGIACMVICTRFISKEILTIREAVWLTDNTYKYE 388
Query: 281 QIRQMEMKILRALNFGLGRPLPLHFLRRASKIGEVDVEQHTLAKYLMELTMLDYDMVHFP 340
+ +M +I+ AL + P + + + V++ L +L EL++L + +
Sbjct: 389 DLVRMMGEIVSALEGKIRVPTVVDYKEVLLTLVPVELRTQHLCSFLCELSLLHTSLSAYA 448
Query: 341 PSQIAAGAFCLALKILDNGE---WTPTLQHYLSYTEESLLPVMQHLAK 385
P+++AA A LA L +G+ WT L ++ E L+P + L K
Sbjct: 449 PARLAAAALLLAR--LTHGQTQPWTTQLWDLTGFSYEDLIPCVLSLHK 494
>gi|16950655 cyclin D1 [Homo sapiens]
Length = 295
Score = 82.4 bits (202), Expect = 7e-16
Identities = 49/167 (29%), Positives = 86/167 (51%), Gaps = 4/167 (2%)
Query: 195 REVTGNMRAILIDWLVQVQMKFRLLQETMYMTVSIIDRFMQNNCVPKKMLQLVGVTAMFI 254
+EV +MR I+ W+++V + + +E + ++ +DRF+ V K LQL+G T MF+
Sbjct: 50 KEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFV 109
Query: 255 ASKYEEMYPPEIGDFAFVTDNTYTKHQIRQMEMKILRALNFGLGRPLPLHFLRR-ASKIG 313
ASK +E P TDN+ ++ QME+ ++ L + L P F+ SK+
Sbjct: 110 ASKMKETIPLTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMP 169
Query: 314 EVDVEQHTLAKY---LMELTMLDYDMVHFPPSQIAAGAFCLALKILD 357
E + + + K+ + L D + PPS +AAG+ A++ L+
Sbjct: 170 EAEENKQIIRKHAQTFVALCATDVKFISNPPSMVAAGSVVAAVQGLN 216
>gi|4502619 cyclin D3 isoform 2 [Homo sapiens]
Length = 292
Score = 79.0 bits (193), Expect = 8e-15
Identities = 61/204 (29%), Positives = 100/204 (49%), Gaps = 16/204 (7%)
Query: 161 GADPNLCSEYVKDIYAYLRQLEEEQAVRPKYL--LGREVTGNMRAILIDWLVQVQMKFRL 218
G DP L + + + L +LEE R Y + RE+ +MR +L W+++V + R
Sbjct: 16 GPDPRLLGD--QRVLQSLLRLEERYVPRASYFQCVQREIKPHMRKMLAYWMLEVCEEQRC 73
Query: 219 LQETMYMTVSIIDRFMQNNCVP--KKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNT 276
+E + ++ +DR++ +CVP K LQL+G M +ASK E P I TD+
Sbjct: 74 EEEVFPLAMNYLDRYL--SCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHA 131
Query: 277 YTKHQIRQMEMKILRALNFGLGRPLPLHF----LRRAS--KIGEVDVEQHTLAKYLMELT 330
+ Q+R E+ +L L + L + F L R S + + V++H A+ + L
Sbjct: 132 VSPRQLRDWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKKH--AQTFLALC 189
Query: 331 MLDYDMVHFPPSQIAAGAFCLALK 354
DY +PPS IA G+ A++
Sbjct: 190 ATDYTFAMYPPSMIATGSIGAAVQ 213
>gi|4502617 cyclin D2 [Homo sapiens]
Length = 289
Score = 70.1 bits (170), Expect = 4e-12
Identities = 45/175 (25%), Positives = 82/175 (46%), Gaps = 4/175 (2%)
Query: 195 REVTGNMRAILIDWLVQVQMKFRLLQETMYMTVSIIDRFMQNNCVPKKMLQLVGVTAMFI 254
+++ MR ++ W+++V + + +E + ++ +DRF+ PK LQL+G MF+
Sbjct: 49 KDIQPYMRRMVATWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFL 108
Query: 255 ASKYEEMYPPEIGDFAFVTDNTYTKHQIRQMEMKILRALNFGLGRPLPLHFLRRASKIGE 314
ASK +E P TDN+ ++ + E+ +L L + L P F+ +
Sbjct: 109 ASKLKETSPLTAEKLCIYTDNSIKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLP 168
Query: 315 VDVEQHTL----AKYLMELTMLDYDMVHFPPSQIAAGAFCLALKILDNGEWTPTL 365
E+ +L A+ + L D+ +PPS IA G+ A+ L E +L
Sbjct: 169 QQREKLSLIRKHAQTFIALCATDFKFAMYPPSMIATGSVGAAICGLQQDEEVSSL 223
>gi|197276674 cyclin J isoform 1 [Homo sapiens]
Length = 383
Score = 57.8 bits (138), Expect = 2e-08
Identities = 55/235 (23%), Positives = 100/235 (42%), Gaps = 28/235 (11%)
Query: 173 DIYAYLRQLEEEQAVRPKYLLGREVTGNMRAILIDWLVQVQMKFRLLQETMYMTVSIIDR 232
DI+ LR E + P Y G+ ++R D + V +F L ++ V ++D
Sbjct: 15 DIHQALRYKELKL---PSYK-GQSPQLSLRRYFADLIAIVSNRFTLCPSARHLAVYLLDL 70
Query: 233 FMQNNCVPKKMLQLVGVTAMFIASKYEEMYP-----PEIGDFAFVTDN--TYTKHQIRQM 285
FM + + L LV ++ + +ASK+EE ++ +T+ TK + M
Sbjct: 71 FMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQNLLHM 130
Query: 286 EMKILRALNFGLGRPLPLHFLR--RASKIGEVDVE--------------QHTLAKYLMEL 329
E+ +L + L P HF+ + + E D+ A Y +E+
Sbjct: 131 ELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAKYADYFLEV 190
Query: 330 TMLDYDMVHFPPSQIAAGAFCLALKILDNGEWTPTLQHYL-SYTEESLLPVMQHL 383
++ DY +++ PS +AA + IL PT H L +Y+ + L+ ++ L
Sbjct: 191 SLQDYAFLNYAPSLVAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCIERL 245
>gi|209862835 cyclin D3 isoform 1 [Homo sapiens]
Length = 211
Score = 55.8 bits (133), Expect = 7e-08
Identities = 42/136 (30%), Positives = 67/136 (49%), Gaps = 12/136 (8%)
Query: 227 VSIIDRFMQNNCVP--KKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNTYTKHQIRQ 284
++ +DR++ +CVP K LQL+G M +ASK E P I TD+ + Q+R
Sbjct: 1 MNYLDRYL--SCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRD 58
Query: 285 MEMKILRALNFGLGRPLPLHF----LRRAS--KIGEVDVEQHTLAKYLMELTMLDYDMVH 338
E+ +L L + L + F L R S + + V++H A+ + L DY
Sbjct: 59 WEVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKKH--AQTFLALCATDYTFAM 116
Query: 339 FPPSQIAAGAFCLALK 354
+PPS IA G+ A++
Sbjct: 117 YPPSMIATGSIGAAVQ 132
>gi|5031703 Ras-GTPase-activating protein SH3-domain-binding protein
[Homo sapiens]
Length = 466
Score = 53.5 bits (127), Expect = 4e-07
Identities = 25/48 (52%), Positives = 34/48 (70%), Gaps = 1/48 (2%)
Query: 93 PVSEPVPEPEPEPEPEPVKE-EKLSPEPILVDTASPSPMETSGCAPAE 139
PV+EP P+PEPEPE EPV E ++ PEP+L +TA ++S APA+
Sbjct: 190 PVAEPEPDPEPEPEQEPVSEIQEEKPEPVLEETAPEDAQKSSSPAPAD 237
Score = 30.8 bits (68), Expect = 2.5
Identities = 30/111 (27%), Positives = 47/111 (42%), Gaps = 14/111 (12%)
Query: 29 TAPAATSKPGLRPRTALGDIGNKVSEQLQAKMPMKKEAKPSATGKVIDKKLPKPLEKVPM 88
TAP K A DI V E L+ + S T K + P+ +P
Sbjct: 222 TAPEDAQKSS---SPAPADIAQTVQEDLRTF------SWASVTSKNLPPSGAVPVTGIPP 272
Query: 89 -LVPVPVSEPVPEPEPE---PEPEPVKEEKLSPEPI-LVDTASPSPMETSG 134
+V VP S+P PE +PE P P +++++ + I + P P+ +G
Sbjct: 273 HVVKVPASQPRPESKPESQIPPQRPQRDQRVREQRINIPPQRGPRPIREAG 323
>gi|38327552 Ras-GTPase-activating protein SH3-domain-binding
protein [Homo sapiens]
Length = 466
Score = 53.5 bits (127), Expect = 4e-07
Identities = 25/48 (52%), Positives = 34/48 (70%), Gaps = 1/48 (2%)
Query: 93 PVSEPVPEPEPEPEPEPVKE-EKLSPEPILVDTASPSPMETSGCAPAE 139
PV+EP P+PEPEPE EPV E ++ PEP+L +TA ++S APA+
Sbjct: 190 PVAEPEPDPEPEPEQEPVSEIQEEKPEPVLEETAPEDAQKSSSPAPAD 237
Score = 30.8 bits (68), Expect = 2.5
Identities = 30/111 (27%), Positives = 47/111 (42%), Gaps = 14/111 (12%)
Query: 29 TAPAATSKPGLRPRTALGDIGNKVSEQLQAKMPMKKEAKPSATGKVIDKKLPKPLEKVPM 88
TAP K A DI V E L+ + S T K + P+ +P
Sbjct: 222 TAPEDAQKSS---SPAPADIAQTVQEDLRTF------SWASVTSKNLPPSGAVPVTGIPP 272
Query: 89 -LVPVPVSEPVPEPEPE---PEPEPVKEEKLSPEPI-LVDTASPSPMETSG 134
+V VP S+P PE +PE P P +++++ + I + P P+ +G
Sbjct: 273 HVVKVPASQPRPESKPESQIPPQRPQRDQRVREQRINIPPQRGPRPIREAG 323
>gi|89886237 cyclin I family, member 2 [Homo sapiens]
Length = 369
Score = 50.4 bits (119), Expect = 3e-06
Identities = 30/101 (29%), Positives = 56/101 (55%), Gaps = 2/101 (1%)
Query: 208 WLVQVQMKFRLLQETMYMTVSIIDRFMQNNCVPKKMLQLVGVTAMFIASKY--EEMYPPE 265
WL+++Q F Q T + ++I R + + V +K L +T++ +A+K EE + P+
Sbjct: 156 WLLRLQNTFYFSQSTFNLALTIFGRLLISVKVKEKYLHCATITSLRLAAKVNEEEEFIPQ 215
Query: 266 IGDFAFVTDNTYTKHQIRQMEMKILRALNFGLGRPLPLHFL 306
+ DF + Y+ +++ +ME+ IL L++ L PL FL
Sbjct: 216 VKDFTKHYGSDYSPNELLRMELAILDRLHWDLYIGTPLDFL 256
>gi|5802992 cyclin I [Homo sapiens]
Length = 377
Score = 48.5 bits (114), Expect = 1e-05
Identities = 33/114 (28%), Positives = 57/114 (50%), Gaps = 2/114 (1%)
Query: 195 REVTGNMRAILIDWLVQVQMKFRLLQETMYMTVSIIDRFMQNNCVPKKMLQLVGVTAMFI 254
+ V+ + R +I WL +++ +F L ET + S++DRF+ K L + ++ F+
Sbjct: 38 QNVSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVKAHPKYLSCIAISCFFL 97
Query: 255 ASK--YEEMYPPEIGDFAFVTDNTYTKHQIRQMEMKILRALNFGLGRPLPLHFL 306
A+K E+ P + A + + +I +ME IL LN+ L PL FL
Sbjct: 98 AAKTVEEDERIPVLKVLARDSFCGCSSSEILRMERIILDKLNWDLHTATPLDFL 151
>gi|5730045 solute carrier family 16, member 2 [Homo sapiens]
Length = 613
Score = 46.6 bits (109), Expect = 4e-05
Identities = 33/111 (29%), Positives = 56/111 (50%), Gaps = 14/111 (12%)
Query: 22 AGAKRVPTAPAATSKPGLRPRTALGDIGNKVSEQLQAKMPMKKEAKPSATG--KVIDKKL 79
+G+ P++ + +S+ +P++ G G S A M ++ +A A G + D++
Sbjct: 40 SGSSSPPSSSSCSSRNKYQPQS--GSSGPS-SHSPPAAMALQSQASEEAKGPWQEADQEQ 96
Query: 80 PKPLEKVPMLVPVPVSEPVPEPEPEPEPEPVKEEKLSPEPILVDTASPSPM 130
+P+ P P SEP PEPEPEP P P E + P+P+ P+P+
Sbjct: 97 QEPVGS-----PEPESEPEPEPEPEPVPVPPPEPQPEPQPL----PDPAPL 138
Score = 45.4 bits (106), Expect = 1e-04
Identities = 30/105 (28%), Positives = 49/105 (46%), Gaps = 2/105 (1%)
Query: 32 AATSKPGLRPRTALGDIGNKVSEQLQAKMPMKKEAKPSATGKVIDKKLPKPLEKVPMLVP 91
+ +S P A + ++ SE+ + + + G + P+P E P VP
Sbjct: 61 SGSSGPSSHSPPAAMALQSQASEEAKGPWQEADQEQQEPVGSPEPESEPEP-EPEPEPVP 119
Query: 92 VPVSEPVPEPEPEPEPEPVKEEKLSPEPILVDTASPSPMETSGCA 136
VP EP PEP+P P+P P+ E + E + +P+ +ET G A
Sbjct: 120 VPPPEPQPEPQPLPDPAPLPELEFESERVHEPEPTPT-VETRGTA 163
>gi|24307909 ral guanine nucleotide dissociation stimulator isoform
1 [Homo sapiens]
Length = 914
Score = 46.2 bits (108), Expect = 6e-05
Identities = 32/86 (37%), Positives = 39/86 (45%), Gaps = 4/86 (4%)
Query: 55 QLQAKMPMKKEAKPSATGKVIDKKLPKPLEKV--PMLVPVPVSEPVPEPEPEPEPEPVKE 112
QL+ P+ EA+P A V K LE P P PV P PEPEP P P P E
Sbjct: 247 QLEHSEPI--EAEPEALSPVPALKPTPELELALTPARAPSPVPAPAPEPEPAPTPAPGSE 304
Query: 113 EKLSPEPILVDTASPSPMETSGCAPA 138
+++P P +P P APA
Sbjct: 305 LEVAPAPAPELQQAPEPAVGLESAPA 330
Score = 31.2 bits (69), Expect = 1.9
Identities = 23/67 (34%), Positives = 28/67 (41%), Gaps = 9/67 (13%)
Query: 80 PKPLEKVPMLVPVPVSE----PVPEPEPEPEPEPVKEEKLSPEPIL----VDTASPSPME 131
P P E P P P SE P P PE + PEP + +P P L P+P +
Sbjct: 289 PAP-EPEPAPTPAPGSELEVAPAPAPELQQAPEPAVGLESAPAPALELEPAPEQDPAPSQ 347
Query: 132 TSGCAPA 138
T PA
Sbjct: 348 TLELEPA 354
Score = 30.8 bits (68), Expect = 2.5
Identities = 29/105 (27%), Positives = 41/105 (39%), Gaps = 8/105 (7%)
Query: 30 APAATSKPGLRPRTALGDIGNKVSEQLQAKMPMKKEAKPSATGKVID-KKLPKP-LEKVP 87
+P KP P L + + A P + A A G ++ P P L++ P
Sbjct: 262 SPVPALKP--TPELELALTPARAPSPVPAPAPEPEPAPTPAPGSELEVAPAPAPELQQAP 319
Query: 88 MLVPVPVSEPVP----EPEPEPEPEPVKEEKLSPEPILVDTASPS 128
S P P EP PE +P P + +L P P V + PS
Sbjct: 320 EPAVGLESAPAPALELEPAPEQDPAPSQTLELEPAPAPVPSLQPS 364
>gi|108796058 ral guanine nucleotide dissociation stimulator isoform
2 [Homo sapiens]
Length = 859
Score = 46.2 bits (108), Expect = 6e-05
Identities = 32/86 (37%), Positives = 39/86 (45%), Gaps = 4/86 (4%)
Query: 55 QLQAKMPMKKEAKPSATGKVIDKKLPKPLEKV--PMLVPVPVSEPVPEPEPEPEPEPVKE 112
QL+ P+ EA+P A V K LE P P PV P PEPEP P P P E
Sbjct: 192 QLEHSEPI--EAEPEALSPVPALKPTPELELALTPARAPSPVPAPAPEPEPAPTPAPGSE 249
Query: 113 EKLSPEPILVDTASPSPMETSGCAPA 138
+++P P +P P APA
Sbjct: 250 LEVAPAPAPELQQAPEPAVGLESAPA 275
Score = 31.2 bits (69), Expect = 1.9
Identities = 23/67 (34%), Positives = 28/67 (41%), Gaps = 9/67 (13%)
Query: 80 PKPLEKVPMLVPVPVSE----PVPEPEPEPEPEPVKEEKLSPEPIL----VDTASPSPME 131
P P E P P P SE P P PE + PEP + +P P L P+P +
Sbjct: 234 PAP-EPEPAPTPAPGSELEVAPAPAPELQQAPEPAVGLESAPAPALELEPAPEQDPAPSQ 292
Query: 132 TSGCAPA 138
T PA
Sbjct: 293 TLELEPA 299
Score = 30.8 bits (68), Expect = 2.5
Identities = 29/105 (27%), Positives = 41/105 (39%), Gaps = 8/105 (7%)
Query: 30 APAATSKPGLRPRTALGDIGNKVSEQLQAKMPMKKEAKPSATGKVID-KKLPKP-LEKVP 87
+P KP P L + + A P + A A G ++ P P L++ P
Sbjct: 207 SPVPALKP--TPELELALTPARAPSPVPAPAPEPEPAPTPAPGSELEVAPAPAPELQQAP 264
Query: 88 MLVPVPVSEPVP----EPEPEPEPEPVKEEKLSPEPILVDTASPS 128
S P P EP PE +P P + +L P P V + PS
Sbjct: 265 EPAVGLESAPAPALELEPAPEQDPAPSQTLELEPAPAPVPSLQPS 309
>gi|4505419 nucleolar protein 3 [Homo sapiens]
Length = 208
Score = 45.8 bits (107), Expect = 8e-05
Identities = 37/92 (40%), Positives = 51/92 (55%), Gaps = 9/92 (9%)
Query: 28 PTAPAA-TSKPGLRPRTALGDI--GNKVSEQLQAKMPMKKEAKPSATGKVIDKKLPKPLE 84
P AP + T+ PGL PR + D G + SE +Q+ P +E +P + + P+P E
Sbjct: 115 PEAPGSGTTCPGL-PRASDPDEAGGPEGSEAVQSGTP--EEPEPELEAEASKEAEPEP-E 170
Query: 85 KVPMLVPVPVSEPVPE--PEPEPEPEPVKEEK 114
P L P +EP PE PEP+PEPEP EE+
Sbjct: 171 PEPELEPEAEAEPEPELEPEPDPEPEPDFEER 202
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 45.1 bits (105), Expect = 1e-04
Identities = 37/111 (33%), Positives = 51/111 (45%), Gaps = 16/111 (14%)
Query: 18 KINMAGAKRVPTAPAATSKPGLRPRTALGDIGNKVSEQLQAKMPMKKEAKPSATGKVIDK 77
KI++A +KRV P P K + + A +P+ K+ +P A
Sbjct: 9273 KIHVAISKRVEPPPKVPELP------------EKPAPEEVAPVPIPKKVEPPAPKVPEVP 9320
Query: 78 KLPKPLEKVPMLVPVPVSEPVPEPE-PEPEPEPVKEEKLSPEPILVDTASP 127
K P P EK P VPVP EP P+ PE +PV EEK+ P P+ +P
Sbjct: 9321 KKPVPEEKKP--VPVPKKEPAAPPKVPEVPKKPVPEEKI-PVPVAKKKEAP 9368
Score = 42.7 bits (99), Expect = 6e-04
Identities = 26/84 (30%), Positives = 46/84 (54%), Gaps = 7/84 (8%)
Query: 61 PMKKEAKPSATGKVIDKKLPKPLEKVPMLVP-VPVSEPVPEPEPEPEPEPVKEEKLSPEP 119
P+++ P+ T + ++K+P+P KVP + P +P+ P P+P+PE E + +K + PEP
Sbjct: 10985 PVEEVEVPTVTKR--ERKIPEPT-KVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEP 11041
Query: 120 ILVDTASPSPM---ETSGCAPAEE 140
+ P+ + AP EE
Sbjct: 11042 TPIAAPVTVPVVGKKAEAKAPKEE 11065
Score = 41.6 bits (96), Expect = 0.001
Identities = 28/74 (37%), Positives = 39/74 (52%), Gaps = 6/74 (8%)
Query: 54 EQLQAKMPMKKEAKPSATGKVIDKKLPKPLEKVPMLVPVPVSEPVPEPEPEPEPEPVKEE 113
E+ +P KKEA P+ +V K P EKVP+L+P +P P PE +PV EE
Sbjct: 9961 EKKPVPVPKKKEAPPAKVPEVPKK----PEEKVPVLIP-KKEKPPPAKVPEVPKKPVPEE 10015
Query: 114 KLSPEPILVDTASP 127
K+ P P+ +P
Sbjct: 10016 KV-PVPVPKKVEAP 10028
Score = 41.6 bits (96), Expect = 0.001
Identities = 30/94 (31%), Positives = 45/94 (47%), Gaps = 4/94 (4%)
Query: 31 PAATSKPGLRPRTALGDIGNKVSEQLQAKMPMKKEAKPSATGKVIDKKLPKPLEKVPMLV 90
P K P + ++ K E++ +P K++ P+ +V K P P EKVP+ V
Sbjct: 9964 PVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEV--PKKPVPEEKVPVPV 10021
Query: 91 PVPVSEPVPEPEPEPEPEPVKEEKLS-PEPILVD 123
P V P P PE +PV E+K+ P P V+
Sbjct: 10022 PKKVEAP-PAKVPEVPKKPVPEKKVPVPAPKKVE 10054
Score = 40.0 bits (92), Expect = 0.004
Identities = 31/102 (30%), Positives = 49/102 (48%), Gaps = 13/102 (12%)
Query: 36 KPGLRPRTALGDIGNKVSEQLQAKMPMKKEAKPSATGKVIDKKLPKPLEKVPMLVPVPVS 95
KP + + +I KV+E+ + +P K+EA P+ +V PK +E+ +++P
Sbjct: 10178 KPKVPVPAPVPEIKKKVTEK-KVVIPKKEEAPPAKVPEV-----PKKVEEKRIILPKEEE 10231
Query: 96 EPVPEPEPEPEPEPVKEEKLSPEPILVDTASPSPMETSGCAP 137
E EPE EP+ EE++ EP PS E AP
Sbjct: 10232 VLPVEVTEEPEEEPISEEEIPEEP-------PSIEEVEEVAP 10266
Score = 38.5 bits (88), Expect = 0.012
Identities = 33/115 (28%), Positives = 46/115 (40%), Gaps = 16/115 (13%)
Query: 14 ENKAKINMAGAKRVPTAPAATSKPGL--------------RPRTALGDIGNKVSEQLQAK 59
E K + +A K P A + G+ P A+ +I K + +
Sbjct: 9354 EEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKVPEERKP 9413
Query: 60 MPMKKEAKPSATGKVIDKKLPKPLEKVPMLVPVPVSEPVPEPEPEPEPEPVKEEK 114
+P K+E P K P P EKV VPVPV++ P P E + V EEK
Sbjct: 9414 VPRKEEEVPPPPKVPALPKKPVPEEKVA--VPVPVAKKAPPPRAEVSKKTVVEEK 9466
Score = 38.5 bits (88), Expect = 0.012
Identities = 32/107 (29%), Positives = 50/107 (46%), Gaps = 18/107 (16%)
Query: 24 AKRVPTAPAATSKPGLRPRTALGDIGNKVSEQLQAKMPMKKEAKPSATGKVI-DKKLPKP 82
+KRV PA ++ + I K+ E AK+P A K++ +KK+P
Sbjct: 9544 SKRVEAEPAEVTERQEKKIVLKPKIPAKIEEPPPAKVP-------EAPKKIVPEKKVPA- 9595
Query: 83 LEKVPMLVPVPVSEPVPEPE-PEPEPEPVKEEKLSPEPILVDTASPS 128
PVP E VP P+ PE +PV E+K+ P+ I ++ P+
Sbjct: 9596 --------PVPKKEKVPPPKVPEEPKKPVPEKKVPPKVIKMEEPLPA 9634
Score = 37.4 bits (85), Expect = 0.027
Identities = 27/89 (30%), Positives = 42/89 (47%), Gaps = 5/89 (5%)
Query: 31 PAATSKPGLRPRTALGDIGNKVSEQLQAKMPMKKEAKPSATGKVIDKKLPKPLEKVPMLV 90
P K P + ++ +V + + +P K E P+ +V K + LE+ P V
Sbjct: 10735 PLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPV---LEEKPA-V 10790
Query: 91 PVPVSEPVPEPEPEPEPEPV-KEEKLSPE 118
PVP P PE EPE + EE+++PE
Sbjct: 10791 PVPERAESPPPEVYEEPEEIAPEEEIAPE 10819
Score = 37.0 bits (84), Expect = 0.035
Identities = 46/176 (26%), Positives = 71/176 (40%), Gaps = 20/176 (11%)
Query: 27 VPTAPAATSKPGLRPRTALGDIGNKVSEQLQAKMPMKKEAKPSATGKVIDKKLPKPLEKV 86
VP A + P P G V+E+ + ++E+ P A ++ KK+P+ + V
Sbjct: 9359 VPVAKKKEAPPAKVPEVQKG----VVTEEKITIVTQREESPPPAVPEIPKKKVPEERKPV 9414
Query: 87 PMLVPVPVSEPVPEPEPEPE--PEPVKEEKLSPEPILVDTASPSPMETSGCAPAEEDLCQ 144
P E VP P P +PV EEK++ + A P E S EE
Sbjct: 9415 PRK-----EEEVPPPPKVPALPKKPVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRFV 9469
Query: 145 AFSDVILAV--------NDVDAEDGADPNLCSEYVK-DIYAYLRQLEEEQAVRPKY 191
A + AV ++V AE+ + E V +Y + EEE+A +Y
Sbjct: 9470 AEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEY 9525
Score = 36.6 bits (83), Expect = 0.046
Identities = 48/190 (25%), Positives = 75/190 (39%), Gaps = 27/190 (14%)
Query: 17 AKINMAGAKRVPT--APAATSKPGLRPRTALGDIGNKV--SEQLQAKMPMKKEAKPSATG 72
AK+ K VP P K P + ++ K +++ P K EA P+
Sbjct: 10002 AKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVP 10061
Query: 73 KVIDKKLPKPLEKVPMLVPVPVS----------EPVPEPE--PEPEPEPVKEEKLSPEPI 120
+V K +P+ EK P VP V EPVP P P+ E +EE + E +
Sbjct: 10062 EVPKKLIPE--EKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEV 10119
Query: 121 LVDTASPSPMETSGCAPAEEDLCQAFSDVILAVNDVDAEDGADPNLCSEYVKDIYAYLRQ 180
L + P E P EE++ ++ +V E+ EYV + ++ +
Sbjct: 10120 LPEEEEVLP-EEEEVLPEEEEVLPEEEEIPPEEEEVPPEE--------EYVPEEEEFVPE 10170
Query: 181 LEEEQAVRPK 190
E V+PK
Sbjct: 10171 EEVLPEVKPK 10180
Score = 36.6 bits (83), Expect = 0.046
Identities = 34/128 (26%), Positives = 49/128 (38%), Gaps = 26/128 (20%)
Query: 28 PTAPAATSKPGLRPRTALGDIGNKVSEQLQAKMPMKKEAKPSATGKVI-------DKKLP 80
P P P P + ++ K+ + + ++P + P+ +V+ +KK+P
Sbjct: 10452 PKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVP 10511
Query: 81 KPLEKVPMLVPVPVSE-----------PVPEPE-PEPEPEPVKE-------EKLSPEPIL 121
P K P P V E PVP P+ PE P V E EK PE I
Sbjct: 10512 VPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIP 10571
Query: 122 VDTASPSP 129
SP P
Sbjct: 10572 PKPESPPP 10579
Score = 36.6 bits (83), Expect = 0.046
Identities = 31/101 (30%), Positives = 42/101 (41%), Gaps = 7/101 (6%)
Query: 36 KPGLRPRTALGDIGNKVSEQLQAKMPMKKEAKPSATGKVIDKKLPKPLEKVPMLVPVPVS 95
KP + L + K E+ + K+ KK K V + PKP+E+V +
Sbjct: 10940 KPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPA-VPEPPPPKPVEEVEVPTVTKRE 10998
Query: 96 EPVPEPEPEPE-----PEPVKEEKLSPEPILVDTASPSPME 131
+PEP PE P P E K PE V T P P+E
Sbjct: 10999 RKIPEPTKVPEIKPAIPLPAPEPKPKPE-AEVKTIKPPPVE 11038
Score = 36.2 bits (82), Expect = 0.060
Identities = 33/100 (33%), Positives = 42/100 (42%), Gaps = 9/100 (9%)
Query: 25 KRVPTAPAATSKPGLRPRTALGDIGNKVSEQ-LQAKMPMKKEAKPSATGKVIDKKLPKPL 83
K+VP AP KP + P V E+ + P K E P+ +V K+ P
Sbjct: 10592 KKVPAAPP--KKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEV--PKVAVPE 10647
Query: 84 EKVPMLVPVPVSEPVPEPEPEPE----PEPVKEEKLSPEP 119
+KVP +P P PE EPE EP E PEP
Sbjct: 10648 KKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEP 10687
Score = 35.8 bits (81), Expect = 0.078
Identities = 39/134 (29%), Positives = 61/134 (45%), Gaps = 17/134 (12%)
Query: 60 MPMKKEAKPSATGKVIDKKLPKPLEKVPMLVPVPVSEPVPEPEPEPEPEPVKEEKL---- 115
+P K +A P+ KV+ K +P+ EKVP VP+P P P+ EP+ V EEK+
Sbjct: 9803 VPTKPKAPPA---KVLKKAVPE--EKVP--VPIPKKLKPPPPKVPEEPKKVFEEKIRISI 9855
Query: 116 --SPEPILVDTASPSPMETSGCAPAEEDLCQAFSDVILAVNDVDAEDGADPNLCS---EY 170
+ + + A+ PM+ AEE + +V V + +P + E
Sbjct: 9856 TKREKEQVTEPAAKVPMKPKRVV-AEEKVPVPRKEVAPPVRVPEVPKELEPEEVAFEEEV 9914
Query: 171 VKDIYAYLRQLEEE 184
V + YL + EEE
Sbjct: 9915 VTHVEEYLVEEEEE 9928
Score = 35.8 bits (81), Expect = 0.078
Identities = 41/142 (28%), Positives = 54/142 (38%), Gaps = 23/142 (16%)
Query: 16 KAKINMAGAKRVPTAPAATSKPGLRPRTALGDIGNKVSEQLQAKMPMKKEAKPSATGKVI 75
K + A VP P K + + KV E + +P +K+ P +
Sbjct: 10024 KVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTP------V 10077
Query: 76 DKKLPKPLEKVPML---VPVPVSEP-----------VPEPEPEPEPE---PVKEEKLSPE 118
KK+ P KVP VPVPV+ P VPE E PE E P +EE L E
Sbjct: 10078 PKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEE 10137
Query: 119 PILVDTASPSPMETSGCAPAEE 140
++ P E P EE
Sbjct: 10138 EEVLPEEEEIPPEEEEVPPEEE 10159
Score = 35.0 bits (79), Expect = 0.13
Identities = 35/153 (22%), Positives = 64/153 (41%), Gaps = 30/153 (19%)
Query: 5 VTRNSKINAENKAKINMAGAKRVPTAPAATSKPGL----RPRTALGDI---------GNK 51
V K+ K ++ A VP P KP + R + ++ +
Sbjct: 10756 VVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEE 10815
Query: 52 VSEQLQAKMPMKKEAKPSATGKVIDKKLPK--PLEKVPMLVPVPVSEPVPEPEPEPEPEP 109
++ + + +P+ +E +P + ++ K P +KVP+ + P + P EPEPE +
Sbjct: 10816 IAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPV-IKKPEAPPPKEPEPE---KV 10871
Query: 110 VKEEKLSPEPILVDTASPSPMETSGCAPAEEDL 142
+++ KL P P P P AP +ED+
Sbjct: 10872 IEKPKLKPRP-----PPPPP------APPKEDV 10893
Score = 33.1 bits (74), Expect = 0.50
Identities = 31/96 (32%), Positives = 40/96 (41%), Gaps = 6/96 (6%)
Query: 25 KRVPTAPAATSKPGLRPRTALGDIGNKVSEQ-LQAKMPMKKEAKPSATGKVIDKKLPKPL 83
K+VP PA KP P V E+ + P K E P+ +V K P
Sbjct: 10508 KKVPVPPA--KKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEV--PKAAVPE 10563
Query: 84 EKVPMLVPVPVSEPVPEPEPEPEPEPVKEEKLSPEP 119
+KVP +P P PE PE E V E+K+ P
Sbjct: 10564 KKVPEAIPPKPESPPPE-VPEAPKEVVPEKKVPAAP 10598
Score = 33.1 bits (74), Expect = 0.50
Identities = 39/131 (29%), Positives = 50/131 (38%), Gaps = 29/131 (22%)
Query: 25 KRVPTAPAA------TSKPGLRPRTALGDIGNKVSEQLQAKMPMKKEAKPSATGKVIDKK 78
K+VP P T P + P+ A+ + KV E + K P A +V+ +K
Sbjct: 10536 KKVPVPPPKKPEVPPTKVPEV-PKAAVPE--KKVPEAIPPKPESPPPEVPEAPKEVVPEK 10592
Query: 79 L-----PKPLEKVPMLVPVPVSEPVPE------PEPEPEPEPVK---------EEKLSPE 118
PK E P+ VP E VPE P +PE P K EK PE
Sbjct: 10593 KVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPE 10652
Query: 119 PILVDTASPSP 129
I SP P
Sbjct: 10653 AIPPKPESPPP 10663
Score = 32.7 bits (73), Expect = 0.66
Identities = 39/137 (28%), Positives = 58/137 (42%), Gaps = 26/137 (18%)
Query: 18 KINMAGAKRVPT--APAATSKPGLRPRTALGDIGNKVSEQLQAKMPMKKEAKPSA-TGKV 74
++ + K VP APA +K P + ++ +V + K+P+ KP A KV
Sbjct: 10692 QVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPE--KKVPLVVPKKPEAPPAKV 10749
Query: 75 --------------IDKKLPKPLEKVPMLVPVPVSE-----PVPEPEPEPEPEPVKE-EK 114
+ KK P KVP + PV E PVPE P PE +E E+
Sbjct: 10750 PEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEE 10809
Query: 115 LSP-EPILVDTASPSPM 130
++P E I + P P+
Sbjct: 10810 IAPEEEIAPEEEKPVPV 10826
Score = 32.3 bits (72), Expect = 0.86
Identities = 25/108 (23%), Positives = 48/108 (44%), Gaps = 2/108 (1%)
Query: 8 NSKINAENKAKINMAGAKRVPTAPAATSKPGLRPRTALGDIGNKVSEQLQAKMPMKKEAK 67
+ ++ AE A++ K++ P +K P + + K+ + + P+ K+ K
Sbjct: 9544 SKRVEAE-PAEVTERQEKKIVLKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEK 9602
Query: 68 PSATGKVIDKKLPKPLEKVPMLVPVPVSEPVPEPEPEPEPEPVKEEKL 115
+ K P P +KVP V + + EP+P E + +EEK+
Sbjct: 9603 VPPPKVPEEPKKPVPEKKVPPKV-IKMEEPLPAKVTERHMQITQEEKV 9649
Score = 31.6 bits (70), Expect = 1.5
Identities = 41/157 (26%), Positives = 66/157 (42%), Gaps = 22/157 (14%)
Query: 17 AKINMAGAKRVPTAPAATSKPGLRPRTALGDIGNKV--SEQLQAKMPMKKEAKPSATGKV 74
AK+ K P K P + ++ K E++ +P K EA P+ +V
Sbjct: 9976 AKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEV 10035
Query: 75 IDKKLPKPLEKVPMLVPVP--VSEP---VPE------PEPEPEPEPVKEEKLSPEPILVD 123
K +P+ + VP P V P VPE PE E +P PV ++ +P P +
Sbjct: 10036 PKKPVPEK----KVPVPAPKKVEAPPAKVPEVPKKLIPE-EKKPTPVPKKVEAPPPKVPK 10090
Query: 124 TASPSPMETSGCAPAEEDLCQAFSDVILAVNDVDAED 160
P P+ + P EE++ F + I+ +V E+
Sbjct: 10091 KREPVPVPVA--LPQEEEV--LFEEEIVPEEEVLPEE 10123
Score = 31.6 bits (70), Expect = 1.5
Identities = 31/114 (27%), Positives = 43/114 (37%), Gaps = 6/114 (5%)
Query: 25 KRVPTAPAATSKPGLRPRTALGDIGNKVSEQLQAKMPMKKEAKPSATGKVIDKKLPKPLE 84
K+VP P K L P G KV + L + P E K K + +K P+ E
Sbjct: 10906 KKVPEKPQVPEKVELTPLKVPGG-EKKVRKLLPERKP---EPKEEVVLKSVLRKRPE--E 10959
Query: 85 KVPMLVPVPVSEPVPEPEPEPEPEPVKEEKLSPEPILVDTASPSPMETSGCAPA 138
+ P + P + + PEP P EE P + P P + PA
Sbjct: 10960 EEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPA 11013
Score = 30.8 bits (68), Expect = 2.5
Identities = 20/74 (27%), Positives = 36/74 (48%), Gaps = 3/74 (4%)
Query: 47 DIGNKVSEQLQAKMPMKKEAKPSATGKVIDKKLPKPLEKVPMLVPVPVSEPVPEPEPEPE 106
++ ++ + + + + K +P + +K P P E P+ +P V P P+ PE
Sbjct: 9263 EVQKEIVTEEKIHVAISKRVEPPPKVPELPEK-PAPEEVAPVPIPKKVEPPAPK-VPEVP 9320
Query: 107 PEPVKEEKLSPEPI 120
+PV EEK P P+
Sbjct: 9321 KKPVPEEK-KPVPV 9333
Score = 30.4 bits (67), Expect = 3.3
Identities = 24/74 (32%), Positives = 36/74 (48%), Gaps = 11/74 (14%)
Query: 54 EQLQAKMPMKKEAKPSAT-----GKVIDKKLP---KPLEKVPMLVPVPVSEPVPEPEPEP 105
E++ + KKEA P+ G V ++K+ + E P VP + VPE E
Sbjct: 9355 EKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKVPE---ER 9411
Query: 106 EPEPVKEEKLSPEP 119
+P P KEE++ P P
Sbjct: 9412 KPVPRKEEEVPPPP 9425
Score = 30.4 bits (67), Expect = 3.3
Identities = 13/33 (39%), Positives = 20/33 (60%)
Query: 52 VSEQLQAKMPMKKEAKPSATGKVIDKKLPKPLE 84
V ++ +AK P ++ AKP K + KK P P+E
Sbjct: 11053 VGKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIE 11085
Score = 28.9 bits (63), Expect = 9.5
Identities = 31/122 (25%), Positives = 45/122 (36%), Gaps = 32/122 (26%)
Query: 25 KRVPTAPAATSKPGLRPRTALGDIGNKVSEQLQAKMPMKKEAK------PSATGKVIDKK 78
K +P P +P+ + K + + +P+ K+ K P KV ++K
Sbjct: 9791 KPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEPKKVFEEK 9850
Query: 79 L------------PKPLEKVPM---------LVPVPVSE-----PVPEPEPEPEPEPVKE 112
+ +P KVPM VPVP E VPE E EPE V
Sbjct: 9851 IRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKELEPEEVAF 9910
Query: 113 EK 114
E+
Sbjct: 9911 EE 9912
Score = 28.9 bits (63), Expect = 9.5
Identities = 30/122 (24%), Positives = 46/122 (37%), Gaps = 16/122 (13%)
Query: 28 PTAPAATSKPGLRPRTALGDIGNKVSEQLQAKMP---------MKKEAKPSA-TGKVIDK 77
P AP + P +P + K + + AK P + KE P V+ K
Sbjct: 10687 PAAPPQVTVPPKKP------VPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPK 10740
Query: 78 KLPKPLEKVPMLVPVPVSEPVPEPEPEPEPEPVKEEKLSPEPILVDTASPSPMETSGCAP 137
K P KVP + V E +PE P K ++ +P+L + + E + P
Sbjct: 10741 KPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPP 10800
Query: 138 AE 139
E
Sbjct: 10801 PE 10802
>gi|41281612 zinc finger protein 828 [Homo sapiens]
Length = 812
Score = 45.1 bits (105), Expect = 1e-04
Identities = 33/111 (29%), Positives = 51/111 (45%), Gaps = 17/111 (15%)
Query: 23 GAKRVPTAPAATSKPGLRPRTALGDIGNKVSEQLQAKMPMKKEAKPSATGKVIDKKLPKP 82
G+ P +P T L P+ G+ VS +LQ +P + +KP++ P+P
Sbjct: 138 GSVLSPESPKPTPLTPLEPQKP----GSVVSPELQTPLPSPEPSKPASVSS------PEP 187
Query: 83 LEKVPMLVPVPVSEPVPEPEPEPEPEPVKEEKLSPEPILVDTASPSPMETS 133
P VPV S+ + P P PEP K +SPE + ++P P + S
Sbjct: 188 ----PKSVPVCESQKLA---PVPSPEPQKPAPVSPESVKATLSNPKPQKQS 231
Score = 33.1 bits (74), Expect = 0.50
Identities = 21/78 (26%), Positives = 31/78 (39%), Gaps = 12/78 (15%)
Query: 72 GKVIDKKLPKPLEKVPM-------LVPVPVSEPVPEPEPEP-----EPEPVKEEKLSPEP 119
G V+ + PKP P+ +V + P+P PEP PEP K +
Sbjct: 138 GSVLSPESPKPTPLTPLEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQ 197
Query: 120 ILVDTASPSPMETSGCAP 137
L SP P + + +P
Sbjct: 198 KLAPVPSPEPQKPAPVSP 215
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.378
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,190,461
Number of Sequences: 37866
Number of extensions: 979877
Number of successful extensions: 11238
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 207
Number of HSP's successfully gapped in prelim test: 353
Number of HSP's that attempted gapping in prelim test: 7107
Number of HSP's gapped (non-prelim): 2643
length of query: 433
length of database: 18,247,518
effective HSP length: 105
effective length of query: 328
effective length of database: 14,271,588
effective search space: 4681080864
effective search space used: 4681080864
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.