Guide to the Human Genome
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Name: CARD18 Sequence: fasta or formatted (90aa) NCBI GI: 10954343
Description:

ICEBERG caspase-1 inhibitor

Referenced in:

BCL2 Pathways, Caspases, and Programmed Cell Death

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.6          5           1
 C cysteine            4.4          4           2
 D aspartate          10.0          9           1
 E glutamate           6.7          6           2
 F phenylalanine       2.2          2           1
 G glycine             5.6          5           1
 H histidine           3.3          3           1
 I isoleucine          6.7          6           1
 K lysine             10.0          9           2
 L leucine            12.2         11           2
 M methionine          4.4          4           1
 N asparagine          3.3          3           1
 P proline             2.2          2           1
 Q glutamine           3.3          3           1
 R arginine            5.6          5           2
 S serine              4.4          4           1
 T threonine           3.3          3           1
 V valine              6.7          6           1
 W tryptophan          0.0          0           0
 Y tyrosine            0.0          0           0
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   ICEBERG caspase-1 inhibitor 
CARD16                0.484   caspase-1 dominant-negative inhibitor pseudo-ICE iso...
CARD16                0.484   caspase-1 dominant-negative inhibitor pseudo-ICE iso...
CASP1                 0.453   caspase 1 isoform alpha precursor 
CASP1                 0.453   caspase 1 isoform beta precursor 
CARD17                0.428   caspase recruitment domain family, member 17 
CARD6                 0.082   caspase recruitment domain family, member 6 
NLRC4                 0.063   caspase recruitment domain protein 12 
CARD8                 0.050   caspase recruitment domain family, member 8 
CASP4                 0.038   caspase 4 isoform alpha precursor 
NOD1                  0.031   nucleotide-binding oligomerization domain containing ...
NOD2                  0.031   nucleotide-binding oligomerization domain containing...
DNAH5                 0.025   dynein, axonemal, heavy chain 5 
CASP1                 0.019   caspase 1 isoform epsilon 
CASP1                 0.013   caspase 1 isoform gamma precursor 
CASP1                 0.013   caspase 1 isoform delta 
CRADD                 0.013   CASP2 and RIPK1 domain containing adaptor with death ...
CASP5                 0.013   caspase 5 isoform b precursor 
SLFN14                0.013   schlafen family member 14 
PTPRN2                0.013   protein tyrosine phosphatase, receptor type, N poly...
PTPRN2                0.013   protein tyrosine phosphatase, receptor type, N poly...
PTPRN2                0.013   protein tyrosine phosphatase, receptor type, N poly...
C6orf182              0.013   hypothetical protein LOC285753 
C6orf182              0.013   hypothetical protein LOC285753 
C6orf174              0.006   hypothetical protein LOC387104 
TFB1M                 0.006   transcription factor B1, mitochondrial 
RFPL4B                0.006   ret finger protein-like 4B 
TDRD1                 0.000   tudor domain containing 1 
DNAH8                 0.000   dynein, axonemal, heavy polypeptide 8 
VPS18                 0.000   vacuolar protein sorting 18 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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